gene_id	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
UHGV-0021853_31	742735.HMPREF9467_00920	6.4e-14	70.9	2EGZP@1|root,33ART@2|Bacteria,1VKPB@1239|Firmicutes,24VDH@186801|Clostridia,221IQ@1506553|Lachnoclostridium	186801|Clostridia	S	YopX protein	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	YopX
UHGV-0021853_34	1122621.ATZA01000001_gene1899	2.33e-101	303.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	Band_7
UHGV-0021853_44	926690.KE386573_gene1812	0.000225	51.6	COG1061@1|root,arCOG00874@2157|Archaea,2XTYQ@28890|Euryarchaeota,23SWE@183963|Halobacteria	183963|Halobacteria	K	COG1061 DNA or RNA helicases of superfamily II	rad25	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	ERCC3_RAD25_C,ResIII
UHGV-0021853_45	1123239.KB898628_gene3227	1.36e-19	93.2	2DR9Y@1|root,33AUY@2|Bacteria,1VEP1@1239|Firmicutes,4HP3X@91061|Bacilli	91061|Bacilli	L	NUMOD4 motif	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	HNH_3,NUMOD4
UHGV-0021853_52	1304866.K413DRAFT_0827	1.71e-27	111.0	2CAZB@1|root,2Z9VC@2|Bacteria,1V2QF@1239|Firmicutes,25DV0@186801|Clostridia	186801|Clostridia	S	AAA domain	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	AAA_24
UHGV-0021853_53	537007.BLAHAN_05280	4.85e-06	55.1	COG3860@1|root,COG3860@2|Bacteria,1UBEF@1239|Firmicutes,258T3@186801|Clostridia,3Y212@572511|Blautia	186801|Clostridia	L	GIY-YIG type nucleases (URI domain)	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	GIY-YIG
UHGV-0021853_56	1443665.JACA01000073_gene2048	1.15e-15	86.3	COG0358@1|root,COG0358@2|Bacteria,4PKG1@976|Bacteroidetes,1I0HN@117743|Flavobacteriia	976|Bacteroidetes	L	Toprim domain protein	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	AAA_25,Toprim_2
UHGV-0021853_60	1415775.U729_3203	9.55e-16	85.1	COG1372@1|root,COG1372@2|Bacteria,1UP4T@1239|Firmicutes,24QYN@186801|Clostridia,36MJM@31979|Clostridiaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL
UHGV-0021853_62	46256.BBIK01000001_gene495	4.19e-11	70.1	COG0476@1|root,COG0476@2|Bacteria,1UYFC@1239|Firmicutes,4IEQP@91061|Bacilli,4AXEW@81850|Leuconostocaceae	91061|Bacilli	H	ThiF family	NULL	NULL	2.7.7.73	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	NULL	R07459	RC00043	ko00000,ko00001,ko01000	NULL	NULL	NULL	ThiF
UHGV-0021853_64	891974.E05_27300	3.88e-24	103.0	COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,1RPDH@1236|Gammaproteobacteria,282HM@191675|unclassified Enterobacteriaceae	1236|Gammaproteobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	NULL	NULL	NULL	ko00000,ko00001,ko01000,ko03400	NULL	NULL	NULL	UDG
UHGV-0021853_66	1033738.CAEP01000137_gene1525	0.000541	46.6	2E3AH@1|root,32YA0@2|Bacteria,1VEBX@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF1064)	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	DUF1064
UHGV-0021853_68	1002367.HMPREF0673_01921	9.2e-176	527.0	COG1328@1|root,COG1328@2|Bacteria,4NFVE@976|Bacteroidetes,2FMF2@200643|Bacteroidia	976|Bacteroidetes	F	Ribonucleoside-triphosphate reductase	nrdD	NULL	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	NULL	NULL	NULL	ATP-cone,NRDD
UHGV-0021853_69	742725.HMPREF9450_00808	2.24e-35	127.0	COG1180@1|root,COG1180@2|Bacteria,4NR4M@976|Bacteroidetes,2G3HA@200643|Bacteroidia,22VEA@171550|Rikenellaceae	976|Bacteroidetes	O	anaerobic ribonucleoside-triphosphate reductase activating protein	nrdG	NULL	1.97.1.4	ko:K04068	NULL	NULL	R04710	NULL	ko00000,ko01000	NULL	NULL	NULL	Fer4_12
UHGV-0021853_70	1218173.BALCAV_0213315	2.25e-38	135.0	COG0756@1|root,COG0756@2|Bacteria,1V5PP@1239|Firmicutes,4HHFX@91061|Bacilli,1ZGRC@1386|Bacillus	91061|Bacilli	F	Deoxyuridine 5'-triphosphate	yncF	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	NULL	NULL	iYO844.BSU17660	dUTPase
UHGV-0021853_72	585543.HMPREF0969_00820	2.08e-09	60.1	29FHY@1|root,302FM@2|Bacteria,4PJIJ@976|Bacteroidetes,2FS19@200643|Bacteroidia,4AQVX@815|Bacteroidaceae	976|Bacteroidetes	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL
UHGV-0021853_73	42256.RradSPS_0202	6.17e-24	114.0	COG0749@1|root,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CP7C@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase	NULL	NULL	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	NULL	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	NULL	NULL	NULL	DNA_pol_A,DNA_pol_A_exo1
UHGV-0021853_74	913865.DOT_5669	6.38e-08	58.2	2E2AR@1|root,309HC@2|Bacteria,1VP2W@1239|Firmicutes,25DRK@186801|Clostridia	186801|Clostridia	L	HNH endonuclease	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL
UHGV-0021853_75	1123311.KB904449_gene206	9.21e-05	50.4	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli	91061|Bacilli	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	NULL	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	NULL	NULL	NULL	5_3_exonuc,5_3_exonuc_N,DNA_pol_A
UHGV-0021853_80	767806.D7PQ37_9CAUD	1.98e-40	141.0	4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses  no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae	10699|Siphoviridae	S	HNH endonuclease	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL
UHGV-0021853_81	1236504.HMPREF2132_11120	3.66e-19	81.3	2EI4V@1|root,33BW7@2|Bacteria	2|Bacteria	S	Protein of unknwon function (DUF3310)	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	DUF3310
UHGV-0021853_88	1122990.BAJH01000002_gene383	1.69e-76	241.0	COG1351@1|root,COG1351@2|Bacteria	2|Bacteria	F	thymidylate synthase (FAD) activity	thyX	GO:0000166,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0036094,GO:0040007,GO:0042083,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050797,GO:0070402,GO:0097159,GO:1901265,GO:1901363	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	NULL	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	NULL	NULL	iNJ661.Rv2754c	Thy1
UHGV-0021853_93	870187.Thini_2738	9.32e-32	142.0	COG0507@1|root,COG0507@2|Bacteria,1QFB2@1224|Proteobacteria,1SE0Z@1236|Gammaproteobacteria,46326@72273|Thiotrichales	72273|Thiotrichales	L	PIF1-like helicase	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	AAA_30,UvrD_C_2,Viral_helicase1
UHGV-0021853_115	1233951.IO90_08605	3.26e-79	283.0	2E9MZ@1|root,333UI@2|Bacteria,4PGWE@976|Bacteroidetes,1IAM2@117743|Flavobacteriia	976|Bacteroidetes	S	CotH kinase protein	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	CotH
UHGV-0021853_119	742735.HMPREF9467_00770	6.21e-18	89.4	2EGKK@1|root,33ACU@2|Bacteria,1VK7U@1239|Firmicutes,24RVS@186801|Clostridia	186801|Clostridia	L	GIY-YIG type nucleases (URI domain)	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	GIY-YIG
UHGV-0021853_131	749413.E5DV63_9VIRU	1.91e-24	103.0	4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses  no RNA stage	10239|Viruses	S	HNH endonuclease	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL
UHGV-0021853_134	523850.TON_0043	5.65e-07	63.2	COG1241@1|root,arCOG03146@1|root,arCOG00439@2157|Archaea,arCOG03146@2157|Archaea,2XT5D@28890|Euryarchaeota,243QT@183968|Thermococci	183968|Thermococci	L	Belongs to the MCM family	NULL	NULL	NULL	ko:K10726	ko03030,map03030	NULL	NULL	NULL	ko00000,ko00001,ko01000,ko03032	NULL	NULL	NULL	HTH_3,Intein_splicing,LAGLIDADG_3,MCM,MCM_N,MCM_OB
UHGV-0021853_142	1007096.BAGW01000002_gene1281	2.28e-08	53.9	2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,2N6EY@216572|Oscillospiraceae	186801|Clostridia	S	GGGtGRT protein	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	NULL	GGGtGRT