These checksum files combine multiple level-1b md5 checksums grouped by WISE scan id. e.g. to check md5 checksums at NERSC: cd /global/homes/c/cosmo/cosmo/data/wise/merge/merge_p1bm_frm md5sum -c /project/projectdirs/cosmo/data/wise/checksums/level1b/02244a.md5 md5sum -c /project/projectdirs/cosmo/data/wise/checksums/level1b/*.md5 [Probably prints more than you actually want; need to wrap a script around this to be very useful]