gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
651660761	468	21.74	11	465	7	411	2.0e-24	107	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
651660763	547	21.75	230	545	49	374	1.0e-16	82	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651660765	345	18.94	1	290	1	297	6.0e-20	91.7	COG1216	Glycosyltransferase, GT2 family	305
651660767	485	22.02	1	485	1	552	7.0e-35	142	COG1256	Flagellar hook-associated protein FlgK	552
651660768	425	32.13	3	425	1	423	1.0e-45	177	COG1749	Flagellar hook protein FlgE	423
651660770	253	33.8	34	244	2	213	4.0e-20	92	COG1843	Flagellar hook assembly protein FlgD	222
651660774	350	30.27	27	282	4	256	3.0e-22	99.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
651660777	427	32.56	57	398	28	356	4.0e-47	182	COG2948	Type IV secretory pathway, VirB10 components	360
651660778	308	22.92	68	304	29	249	2.0e-14	73.1	COG3504	Type IV secretory pathway, VirB9 components	265
651660779	394	42.52	23	393	43	418	4.0e-63	235	COG4102	Uncharacterized conserved protein, DUF1501 family	418
651660780	300	23.86	1	295	1	305	1.0e-22	100	COG1216	Glycosyltransferase, GT2 family	305
651660782	295	34.32	1	295	1	294	3.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
651660784	658	18.66	1	281	9	286	2.0e-08	54.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
651660786	206	41.55	4	206	8	207	1.0e-42	166	COG0352	Thiamine monophosphate synthase	211
651660787	304	33.7	18	291	6	250	3.0e-43	169	COG1830	Fructose-bisphosphate aldolase class Ia, DhnA family	265
651660791	383	27.67	22	310	13	310	2.0e-24	107	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
651660792	327	64.16	20	311	2	294	2.0e-115	409	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
651660793	647	58.25	5	631	2	624	0.0e+00	888	COG1154	Deoxyxylulose-5-phosphate synthase	627
651660794	204	23.41	1	198	6	202	8.0e-15	73.8	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
651660795	397	22.65	22	378	34	384	8.0e-19	88.5	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
651660797	267	29.06	7	267	5	242	8.0e-25	107	COG3394	Predicted glycoside hydrolase or deacetylase ChbG, UPF0249 family	257
651660799	116	29.06	2	116	32	148	7.0e-12	62.6	COG1981	Uncharacterized membrane protein	149
651660802	446	21.08	79	279	41	220	4.0e-11	63.1	COG1462	Curli biogenesis system outer membrane secretion channel CsgG	252
651660806	203	24.71	13	184	65	229	2.0e-14	72.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
651660809	775	16.84	16	751	33	757	4.0e-28	120	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
651660814	145	33.6	7	122	3	127	5.0e-12	63.5	COG2165	Type II secretory pathway, pseudopilin PulG	149
651660816	519	34.41	12	517	4	521	0.0e+00	465	COG1384	Lysyl-tRNA synthetase, class I	521
651660817	530	36.02	99	259	1	157	9.0e-26	112	COG3436	Transposase	157
651660818	217	29.32	78	207	1	130	1.0e-12	66.6	COG3436	Transposase	157
651660823	419	30.69	22	385	1	372	2.0e-49	190	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
651660824	446	34.35	1	445	2	443	2.0e-109	389	COG0174	Glutamine synthetase	443
651660825	354	41.53	5	352	10	360	6.0e-72	264	COG0687	Spermidine/putrescine-binding periplasmic protein	363
651660826	280	39.86	2	273	1	265	3.0e-45	175	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
651660827	310	38.16	25	307	9	286	6.0e-50	191	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
651660828	398	49.16	47	396	4	350	1.0e-108	386	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
651660829	371	67.39	1	371	1	371	0.0e+00	529	COG0686	Alanine dehydrogenase	371
651660831	458	47.11	9	453	4	449	0.0e+00	530	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
651660832	453	33.77	16	452	14	443	8.0e-96	344	COG0174	Glutamine synthetase	443
651660833	362	48.58	56	337	16	292	1.0e-75	276	COG1533	DNA repair photolyase	297
651660834	480	47.01	12	343	2	333	4.0e-112	398	COG0836	Mannose-1-phosphate guanylyltransferase	333
651660835	268	25.2	12	254	4	234	5.0e-21	95	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
651660837	231	42.98	1	225	4	229	1.0e-54	206	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
651660838	315	51.57	21	303	4	284	3.0e-92	331	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
651660841	308	39.03	1	303	5	306	4.0e-55	208	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
651660842	231	36.68	6	200	13	205	2.0e-12	66.2	COG1994	Zn-dependent protease (includes SpoIVFB)	230
651660843	264	35.57	13	262	1	245	1.0e-36	146	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
651660844	185	44.51	14	173	10	172	1.0e-37	149	COG1386	Chromosome segregation and condensation protein ScpB	184
651660845	147	37.31	1	67	1	67	2.0e-10	58	COG1826	Sec-independent protein translocase protein TatA	94
651660846	268	45.67	13	266	1	248	8.0e-61	227	COG0805	Sec-independent protein secretion pathway component TatC	255
651660847	433	54.69	1	433	1	426	0.0e+00	542	COG0172	Seryl-tRNA synthetase	429
651660848	289	28.04	1	208	8	211	5.0e-24	104	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
651660851	255	57.81	1	254	5	260	1.0e-85	309	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
651660852	68	49.23	6	68	5	68	7.0e-09	52.1	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
651660853	373	33.85	1	372	5	387	8.0e-41	161	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
651660854	606	65.28	124	579	3	432	0.0e+00	726	COG0422	Thiamine biosynthesis protein ThiC	432
651660856	222	40.85	10	220	5	217	1.0e-48	186	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
651660857	314	43.71	1	312	20	335	2.0e-68	252	COG2951	Membrane-bound lytic murein transglycosylase B	343
651660859	352	41	15	348	1	337	3.0e-71	262	COG2008	Threonine aldolase	342
651660860	156	45.14	1	142	1	144	1.0e-43	169	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
651660861	320	61.41	16	313	9	306	0.0e+00	470	COG0320	Lipoate synthase	306
651660862	465	46.93	2	454	1	453	0.0e+00	479	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
651660863	169	28.26	15	147	3	137	4.0e-09	54.5	COG1247	L-amino acid N-acyltransferase YncA	169
651660868	323	40.47	23	313	18	314	3.0e-61	228	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
651660869	340	24.7	1	332	3	293	6.0e-18	85.5	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
651660870	434	19.68	10	434	21	447	2.0e-21	97.6	COG2271	Sugar phosphate permease	448
651660871	226	39.81	17	222	10	210	9.0e-41	160	COG0684	Regulator of RNase E activity RraA	210
651660872	302	38.87	1	298	1	292	3.0e-37	149	COG0583	DNA-binding transcriptional regulator, LysR family	297
651660873	266	29.14	2	265	6	278	1.0e-35	143	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
651660874	1214	51.41	702	1214	2	522	0.0e+00	621	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
651660875	146	50.34	1	145	54	198	2.0e-42	164	COG5631	Predicted transcription regulator, contains HTH domain, MarR family	199
651660876	421	26.4	42	414	26	392	4.0e-15	76.4	COG2814	Predicted arabinose efflux permease, MFS family	394
651660881	298	44.23	215	266	5	56	3.0e-08	52.7	COG2771	DNA-binding transcriptional regulator, CsgD family	65
651660882	538	21.25	37	510	2	455	7.0e-29	122	COG0531	Amino acid transporter	466
651660883	255	35.97	3	249	1	247	8.0e-35	140	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651660884	415	18.62	22	414	31	459	1.0e-34	140	COG0277	FAD/FMN-containing dehydrogenase	459
651660885	105	29.36	1	105	46	153	2.0e-10	57.8	COG1522	DNA-binding transcriptional regulator, Lrp family	154
651660886	103	18.18	1	98	13	107	3.0e-05	40	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
651660888	128	26.98	3	128	1	123	2.0e-07	48.2	COG3293	Transposase	124
651660889	292	34.29	189	292	18	122	2.0e-21	96.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
651660890	307	19.5	3	284	10	286	2.0e-03	37.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
651660891	474	28.38	23	458	11	447	2.0e-49	190	COG2079	2-methylcitrate dehydratase PrpD	453
651660892	413	45.93	17	394	1	376	5.0e-96	345	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
651660893	252	31.35	2	242	5	248	2.0e-34	139	COG1809	Phosphosulfolactate synthase, CoM biosynthesis protein A	258
651660894	312	24.51	9	258	2	247	5.0e-24	105	COG1378	Sugar-specific transcriptional regulator TrmB	247
651660895	508	21.09	5	507	3	423	3.0e-23	103	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
651660896	332	29.1	66	329	69	335	6.0e-33	135	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
651660897	278	31.92	10	269	1	253	1.0e-36	146	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
651660898	275	34.17	30	269	17	252	2.0e-34	139	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
651660899	274	48.79	19	266	3	243	4.0e-81	294	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
651660900	140	27.27	8	137	1	132	2.0e-15	75.1	COG3335	Transposase	132
651660901	246	27.08	17	156	1	124	4.0e-10	58.6	COG3293	Transposase	124
651660904	205	32.37	5	205	24	230	6.0e-21	94.3	COG0790	TPR repeat	292
651660909	525	22.65	27	461	1	445	9.0e-23	102	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
651660910	641	27.65	1	627	1	537	3.0e-92	332	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
651660912	368	28.34	7	356	3	374	7.0e-27	115	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651660915	308	29.37	9	293	4	257	2.0e-28	119	COG0584	Glycerophosphoryl diester phosphodiesterase	257
651660916	588	41.06	15	588	30	602	0.0e+00	533	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
651660919	283	30	33	280	5	250	7.0e-29	121	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
651660925	217	34.72	1	216	2	203	1.0e-24	106	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
651660927	192	37.77	1	186	10	197	1.0e-33	136	COG3548	Uncharacterized membrane protein	197
651660929	301	39.58	10	293	3	279	5.0e-56	211	COG0142	Geranylgeranyl pyrophosphate synthase	322
651660930	93	42.42	20	85	5	70	9.0e-10	55.3	COG1722	Exonuclease VII small subunit	81
651660931	309	45.83	1	307	2	310	6.0e-81	294	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
651660932	92	33.78	3	75	5	78	7.0e-12	62.2	COG0425	TusA-related sulfurtransferase	78
651660933	298	37.34	1	295	5	305	9.0e-53	200	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
651660934	256	46.01	6	256	8	267	1.0e-64	239	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
651660935	514	46.77	7	513	5	485	0.0e+00	486	COG0260	Leucyl aminopeptidase	485
651660937	175	42.24	15	175	6	165	3.0e-26	111	COG2862	Uncharacterized membrane protein YqhA	169
651660939	110	42.19	4	63	5	66	6.0e-08	49.4	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
651660940	292	47.5	130	289	1	160	1.0e-45	176	COG1329	RNA polymerase-interacting regulator, CarD/CdnL/TRCF family	166
651660941	433	42.89	25	426	10	413	5.0e-70	258	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
651660944	660	54.33	403	655	2	250	6.0e-79	288	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
651660945	309	41.97	2	305	1	294	2.0e-48	186	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
651660946	454	32.43	68	434	4	356	2.0e-40	160	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
651660947	671	27.74	14	666	5	605	4.0e-65	243	COG4206	Outer membrane cobalamin receptor protein	608
651660948	227	32.14	7	224	4	226	4.0e-28	118	COG1011	FMN phosphatase YigB, HAD superfamily	229
651660949	232	27.75	20	220	9	195	1.0e-12	67.2	COG0625	Glutathione S-transferase	211
651660951	212	22.16	12	204	5	196	3.0e-09	55.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
651660953	309	44.3	3	307	2	304	5.0e-82	297	COG0196	FAD synthase	304
651660954	153	36.36	1	135	11	153	5.0e-20	90.5	COG2030	Acyl dehydratase	159
651660955	310	20.31	6	259	3	255	2.0e-10	60.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
651660958	465	23.71	22	444	6	387	3.0e-12	66.8	COG2814	Predicted arabinose efflux permease, MFS family	394
651660959	307	32.78	10	304	3	299	3.0e-44	172	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
651660960	428	28.81	16	423	6	404	1.0e-39	157	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
651660962	273	24.73	68	249	69	235	3.0e-07	49.2	COG5031	Ubiquinone biosynthesis protein Coq4	235
651660963	317	32.89	7	310	8	305	4.0e-43	168	COG0650	Formate hydrogenlyase subunit 4	309
651660964	226	24.27	22	226	16	218	4.0e-10	58.7	COG4237	Hydrogenase-4 membrane subunit HyfE	218
651660965	506	31.81	1	468	2	474	5.0e-48	185	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
651660966	470	35	117	470	10	367	3.0e-70	259	COG3261	Ni,Fe-hydrogenase III large subunit	382
651660967	266	47.86	124	262	3	142	2.0e-43	169	COG3260	Ni,Fe-hydrogenase III small subunit	148
651660968	658	27.27	5	482	7	475	4.0e-29	123	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
651660969	115	37.86	1	103	1	102	4.0e-20	89.9	COG1993	PII-like signaling protein	109
651660970	138	46.6	6	108	5	107	2.0e-28	118	COG1993	PII-like signaling protein	109
651660981	417	18.65	95	397	1	303	5.0e-07	49.6	COG0582	Integrase	309
651660983	264	58.46	1	259	1	260	3.0e-103	368	COG3718	5-deoxy-D-glucuronate isomerase	270
651660984	612	61.04	1	610	1	616	0.0e+00	844	COG3962	TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism	617
651660985	636	53.05	331	635	1	310	1.0e-103	370	COG3892	Myo-inositol catabolism protein IolC	310
651660987	355	31.5	28	352	2	314	4.0e-41	162	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651660988	322	29.68	23	320	18	322	1.0e-29	123	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651660989	262	57.3	1	261	5	271	2.0e-88	319	COG4130	Predicted sugar epimerase, xylose isomerase-like family	272
651660990	336	25.3	1	316	2	331	1.0e-42	167	COG0673	Predicted dehydrogenase	342
651660991	320	31.67	19	310	1	274	8.0e-41	161	COG1082	Sugar phosphate isomerase/epimerase	274
651660992	328	23.38	44	316	38	314	4.0e-23	102	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651660997	192	49.18	1	182	1	183	2.0e-42	165	COG4341	Predicted HD phosphohydrolase	186
651661000	200	35.85	31	188	3	161	7.0e-28	117	COG1329	RNA polymerase-interacting regulator, CarD/CdnL/TRCF family	166
651661001	68	55.88	1	68	1	67	3.0e-22	96.7	COG1278	Cold shock protein, CspA family	67
651661005	251	45.61	14	251	6	242	1.0e-25	110	COG0368	Cobalamin synthase	246
651661006	342	44.44	14	340	2	334	4.0e-69	255	COG2038	NaMN:DMB phosphoribosyltransferase	347
651661007	166	52.87	1	166	1	174	1.0e-52	199	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
651661008	310	28.43	36	137	20	121	8.0e-11	61.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
651661009	282	32.64	1	279	1	277	6.0e-30	124	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
651661012	641	59.27	9	605	1	595	0.0e+00	760	COG0465	ATP-dependent Zn proteases	596
651661013	292	35.76	4	288	2	284	6.0e-44	171	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
651661014	253	32.28	1	250	2	254	5.0e-25	108	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
651661015	716	63.74	1	694	1	692	0.0e+00	979	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
651661016	404	47.07	11	403	1	391	1.0e-74	274	COG2807	Cyanate permease	395
651661018	133	41.04	1	133	7	136	4.0e-13	66.9	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
651661020	187	39.87	4	161	1	151	5.0e-42	164	COG0242	Peptide deformylase	168
651661021	219	28.06	7	200	19	214	4.0e-26	111	COG5590	Ubiquinone biosynthesis protein COQ9	229
651661022	407	40.25	15	407	1	387	2.0e-60	226	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
651661031	442	42.15	6	442	4	445	0.0e+00	471	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
651661032	299	22.87	11	298	2	290	2.0e-26	113	COG0583	DNA-binding transcriptional regulator, LysR family	297
651661033	417	25.94	17	417	4	409	7.0e-49	188	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
651661034	428	36.31	3	323	1	310	2.0e-77	283	COG0167	Dihydroorotate dehydrogenase	310
651661035	416	36.77	1	412	13	450	2.0e-86	313	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
651661036	222	25	12	201	1	186	4.0e-06	45	COG1309	DNA-binding transcriptional regulator, AcrR family	201
651661037	497	32.29	6	453	1	430	2.0e-95	343	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
651661038	505	37.16	27	496	20	489	8.0e-99	354	COG1953	Cytosine/uracil/thiamine/allantoin permease	497
651661044	518	37.74	80	237	3	157	1.0e-19	91.3	COG3436	Transposase	157
651661046	222	34.1	1	212	3	217	4.0e-46	178	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
651661047	342	36.99	1	313	2	317	6.0e-46	178	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651661048	340	44.52	29	338	6	313	1.0e-53	203	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651661049	535	44.05	24	526	4	500	0.0e+00	505	COG1129	ABC-type sugar transport system, ATPase component	500
651661050	509	47.4	1	492	9	498	0.0e+00	483	COG0578	Glycerol-3-phosphate dehydrogenase	532
651661051	271	16.67	15	261	3	261	1.0e-11	63.6	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
651661052	450	30.11	41	316	8	282	7.0e-35	141	COG0371	Glycerol dehydrogenase or related enzyme, iron-containing ADH family	360
651661053	325	44.37	18	325	9	318	2.0e-77	282	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
651661054	497	37.27	5	496	4	500	2.0e-89	323	COG1070	Sugar (pentulose or hexulose) kinase	502
651661055	129	36.44	1	117	1	117	3.0e-12	63.8	COG3415	Transposase	138
651661056	185	26.72	63	176	1	116	5.0e-09	54.7	COG3335	Transposase	132
651661057	208	34.33	1	195	11	206	5.0e-32	130	COG3531	Predicted protein-disulfide isomerase , contains CxxC motif	212
651661058	394	46.17	6	394	6	396	2.0e-121	429	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
651661059	90	46.59	1	88	1	88	3.0e-11	60.3	COG0268	Ribosomal protein S20	88
651661060	427	45.61	3	423	24	408	1.0e-114	406	COG0593	Chromosomal replication initiation ATPase DnaA	408
651661061	283	39.29	6	283	6	312	4.0e-67	248	COG0627	S-formylglutathione hydrolase FrmB	316
651661062	67	65.67	1	67	1	67	2.0e-22	97.1	COG1278	Cold shock protein, CspA family	67
651661063	144	37.9	23	144	1	115	4.0e-14	70.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
651661064	378	43.4	1	376	1	390	3.0e-73	269	COG0183	Acetyl-CoA acetyltransferase	392
651661065	786	33.33	3	312	2	302	8.0e-63	235	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
651661070	254	37.3	9	239	8	249	5.0e-22	98.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651661072	202	36.13	2	192	7	192	9.0e-32	130	COG0576	Molecular chaperone GrpE (heat shock protein)	193
651661073	635	63.06	1	600	4	579	0.0e+00	697	COG0443	Molecular chaperone DnaK (HSP70)	579
651661074	383	57.29	1	382	1	371	0.0e+00	469	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
651661076	609	33.33	15	448	6	443	1.0e-54	208	COG0038	H+/Cl- antiporter ClcA	443
651661077	153	30.84	18	124	1	104	2.0e-06	45.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
651661079	749	28.35	352	596	3	255	3.0e-29	124	COG1216	Glycosyltransferase, GT2 family	305
651661082	264	26.79	1	263	25	286	8.0e-20	91.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
651661084	808	33.37	26	789	53	870	0.0e+00	495	COG3002	Uncharacterized conserved protein YbcC, UPF0753/DUF2309 family	880
651661085	373	30.75	1	373	1	341	4.0e-51	195	COG0673	Predicted dehydrogenase	342
651661086	330	37.65	1	330	3	340	5.0e-55	208	COG0673	Predicted dehydrogenase	342
651661087	328	40.91	1	307	3	309	3.0e-68	252	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
651661088	263	36.82	1	254	2	254	2.0e-51	196	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
651661089	314	32.47	17	283	3	263	6.0e-38	151	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
651661090	303	30.41	7	294	3	274	2.0e-30	126	COG1082	Sugar phosphate isomerase/epimerase	274
651661091	270	38.74	5	253	3	247	2.0e-38	153	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651661094	392	26.93	2	389	36	455	7.0e-37	148	COG0277	FAD/FMN-containing dehydrogenase	459
651661095	486	42.73	22	472	2	459	3.0e-90	326	COG0277	FAD/FMN-containing dehydrogenase	459
651661098	301	33.8	3	284	2	284	4.0e-56	211	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
651661099	246	60.85	11	244	4	238	6.0e-87	313	COG0528	Uridylate kinase	238
651661100	188	52.69	3	188	2	187	3.0e-58	218	COG0233	Ribosome recycling factor	187
651661101	254	53.68	9	239	13	243	3.0e-81	294	COG0020	Undecaprenyl pyrophosphate synthase	245
651661102	231	35.65	17	213	39	254	5.0e-26	111	COG0575	CDP-diglyceride synthetase	265
651661105	504	41.82	11	504	5	497	0.0e+00	515	COG2317	Zn-dependent carboxypeptidase, M32 family	497
651661106	238	29.39	1	232	1	240	1.0e-26	113	COG3346	Cytochrome oxidase assembly protein ShyY1	252
651661107	283	39.9	69	276	10	207	5.0e-39	155	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
651661108	317	49.03	11	317	1	299	8.0e-82	297	COG0109	Polyprenyltransferase (heme O synthase)	304
651661109	532	56.81	15	531	1	517	0.0e+00	555	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
651661110	316	29.1	45	285	17	239	3.0e-47	182	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
651661115	444	36.57	8	436	1	415	7.0e-112	397	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
651661118	543	24.81	4	512	41	529	6.0e-48	185	COG2831	Hemolysin activation/secretion protein	554
651661119	646	33.21	1	543	6	548	5.0e-107	382	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
651661121	453	30.04	1	445	1	424	9.0e-50	191	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
651661122	156	32.26	3	156	6	158	1.0e-21	95.7	COG3521	Predicted component of the type VI protein secretion system	159
651661123	443	51.12	1	443	1	446	0.0e+00	487	COG3522	Predicted component of the type VI protein secretion system	446
651661126	228	49.32	2	222	1	219	6.0e-60	223	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
651661128	567	25.14	214	567	86	431	5.0e-24	106	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
651661129	287	34.91	1	274	11	282	4.0e-52	198	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
651661130	269	32.12	2	267	77	348	1.0e-41	163	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
651661131	359	29.44	10	352	1	377	2.0e-62	233	COG1454	Alcohol dehydrogenase, class IV	377
651661132	286	28.57	57	282	1	215	1.0e-31	130	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
651661135	682	50.59	9	676	2	665	0.0e+00	795	COG0272	NAD-dependent DNA ligase	667
651661136	138	55	18	137	1	120	9.0e-27	112	COG1734	RNA polymerase-binding transcription factor DksA	120
651661138	384	53.71	36	384	18	365	3.0e-107	381	COG1706	Flagellar basal body P-ring protein FlgI	365
651661141	334	27.21	54	332	95	373	3.0e-23	103	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651661142	568	26.18	146	414	77	331	2.0e-32	134	COG0642	Signal transduction histidine kinase	336
651661144	641	25.99	13	617	9	620	1.0e-65	244	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
651661145	263	39.3	1	257	1	252	5.0e-42	165	COG0390	ABC-type iron transport system FetAB, permease component	256
651661146	199	33.51	17	197	21	213	7.0e-28	117	COG4619	ABC-type iron transport system FetAB, ATPase component	223
651661147	468	25.85	7	468	2	408	8.0e-49	188	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
651661148	95	51.58	1	95	2	96	5.0e-27	112	COG2154	Pterin-4a-carbinolamine dehydratase	101
651661149	212	27.55	13	200	4	198	1.0e-34	139	COG1573	Uracil-DNA glycosylase	202
651661150	219	25.6	12	209	5	209	3.0e-14	71.8	COG0625	Glutathione S-transferase	211
651661151	336	27.78	63	314	50	312	1.0e-23	104	COG0657	Acetyl esterase/lipase	312
651661156	303	35.57	1	295	1	289	1.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
651661157	212	42.56	18	211	6	198	9.0e-54	203	COG0740	ATP-dependent protease ClpP, protease subunit	200
651661158	380	53.83	3	368	1	356	3.0e-94	339	COG3288	NAD/NADP transhydrogenase alpha subunit	356
651661160	472	59.11	9	470	6	463	0.0e+00	572	COG1282	NAD/NADP transhydrogenase beta subunit	463
651661161	462	56.83	6	459	1	451	0.0e+00	556	COG0541	Signal recognition particle GTPase	451
651661162	114	65.85	2	83	1	80	3.0e-26	110	COG0228	Ribosomal protein S16	87
651661163	169	31.76	3	159	5	166	5.0e-24	104	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
651661164	234	52.65	3	226	1	226	3.0e-90	324	COG0336	tRNA G37 N-methylase TrmD	240
651661165	123	61.21	1	116	3	113	2.0e-37	147	COG0335	Ribosomal protein L19	115
651661166	571	32.12	7	496	37	513	2.0e-94	340	COG0513	Superfamily II DNA and RNA helicase	513
651661171	373	48.53	5	373	4	377	5.0e-102	364	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
651661174	74	50	8	71	1	64	8.0e-11	58.7	COG0291	Ribosomal protein L35	65
651661175	118	62.61	1	115	1	115	8.0e-37	145	COG0292	Ribosomal protein L20	118
651661176	350	27.18	10	346	3	381	7.0e-26	111	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651661177	275	37.04	13	252	1	237	8.0e-58	217	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
651661178	139	26.19	10	129	7	122	2.0e-04	38.8	COG3631	Ketosteroid isomerase-related protein	133
651661179	334	52.54	1	334	4	338	5.0e-120	424	COG2130	NADPH-dependent curcumin reductase CurA	340
651661180	261	48	11	256	1	250	2.0e-77	282	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
651661181	230	49.36	1	230	3	237	7.0e-77	280	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
651661182	411	24.66	26	387	3	366	4.0e-34	139	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
651661183	295	40.97	12	293	6	292	2.0e-41	162	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
651661184	311	33.44	1	308	2	313	1.0e-41	163	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
651661185	493	36.58	3	491	1	475	4.0e-91	328	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
651661189	379	38.79	1	375	1	346	2.0e-65	243	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
651661192	249	35.75	30	233	3	209	1.0e-32	133	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
651661194	337	36.87	6	332	50	387	2.0e-73	269	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
651661196	451	28.57	16	451	9	426	9.0e-49	188	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
651661197	601	70.22	1	600	1	601	0.0e+00	1062	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
651661198	943	29.86	441	764	69	428	4.0e-39	157	COG0166	Glucose-6-phosphate isomerase	446
651661199	334	54.49	1	323	1	297	3.0e-108	385	COG1023	6-phosphogluconate dehydrogenase (decarboxylating)	300
651661200	505	49.8	1	494	11	481	0.0e+00	569	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
651661201	272	30.19	7	269	5	263	2.0e-43	169	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
651661202	242	34.57	4	237	2	233	5.0e-44	171	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
651661203	424	46.67	4	224	2	223	5.0e-58	218	COG0120	Ribose 5-phosphate isomerase	227
651661204	594	30.56	4	588	15	606	6.0e-98	352	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
651661205	353	43.77	1	353	4	348	7.0e-95	340	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
651661206	466	16.63	49	459	37	437	7.0e-05	42.5	COG2271	Sugar phosphate permease	448
651661207	455	27.33	13	451	5	449	1.0e-58	221	COG2079	2-methylcitrate dehydratase PrpD	453
651661208	235	38.71	2	217	3	218	5.0e-29	121	COG1802	DNA-binding transcriptional regulator, GntR family	230
651661209	384	45.89	1	377	1	371	4.0e-99	355	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
651661214	492	49.25	19	485	2	465	0.0e+00	507	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
651661215	529	27.56	2	527	21	607	8.0e-49	188	COG3211	Secreted phosphatase, PhoX family	616
651661216	165	27.97	5	143	5	146	6.0e-15	73.9	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
651661218	357	46.87	1	332	1	334	1.0e-95	343	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
651661219	320	56.79	1	320	1	322	4.0e-110	391	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
651661220	104	41.76	3	93	1	91	1.0e-24	104	COG0776	Bacterial nucleoid DNA-binding protein	94
651661223	254	66.53	3	252	6	256	6.0e-93	333	COG4107	ABC-type phosphonate transport system, ATPase component	258
651661224	277	73.36	1	274	9	282	0.0e+00	479	COG3627	Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase	291
651661225	360	65.74	1	358	1	358	0.0e+00	516	COG3626	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI	367
651661226	151	41.94	2	149	41	195	2.0e-22	98.5	COG3625	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH	196
651661227	147	46.26	1	145	6	150	1.0e-30	125	COG3624	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG	151
651661229	405	20.95	17	390	31	387	1.0e-11	64.8	COG2814	Predicted arabinose efflux permease, MFS family	394
651661234	64	33.93	3	58	18	73	2.0e-07	47.7	COG0690	Preprotein translocase subunit SecE	73
651661235	176	53.67	1	176	1	177	1.0e-50	192	COG0250	Transcription antitermination factor NusG	178
651661236	300	26.46	6	292	1	282	4.0e-17	82.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
651661237	140	29.03	19	140	36	157	2.0e-08	51.6	COG2030	Acyl dehydratase	159
651661238	292	56.1	3	288	1	286	1.0e-111	396	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
651661239	472	35.56	19	458	13	459	7.0e-93	334	COG1109	Phosphomannomutase	464
651661240	333	47.63	1	311	5	314	3.0e-95	341	COG0180	Tryptophanyl-tRNA synthetase	314
651661241	349	46.06	33	347	5	316	6.0e-53	201	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651661242	345	30.82	6	321	3	317	3.0e-38	152	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651661244	274	29.88	12	251	3	243	3.0e-24	105	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
651661245	456	20.19	19	430	12	384	4.0e-07	49.8	COG2814	Predicted arabinose efflux permease, MFS family	394
651661247	926	25.04	205	892	13	621	1.0e-63	238	COG1199	Rad3-related DNA helicase	654
651661248	168	33.72	2	167	44	200	6.0e-19	87	COG1573	Uracil-DNA glycosylase	202
651661249	190	37.43	7	181	6	177	6.0e-33	134	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
651661250	168	38.69	1	168	1	158	1.0e-31	129	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
651661251	136	43.84	1	71	1	73	2.0e-11	61.5	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
651661252	756	41.6	30	753	9	700	0.0e+00	748	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
651661253	134	46.56	1	131	1	126	2.0e-35	141	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
651661255	145	23.85	9	137	6	133	1.0e-05	42.5	COG3431	Uncharacterized membrane protein, DUF373 family	142
651661256	183	67.82	10	183	2	175	1.0e-75	275	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
651661257	439	61.57	6	439	3	444	0.0e+00	619	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
651661258	114	27.52	7	112	15	115	3.0e-08	50.3	COG3462	Uncharacterized membrane protein	117
651661259	473	36.79	1	459	1	465	4.0e-72	265	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
651661260	427	28.31	9	424	2	409	3.0e-45	176	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
651661261	416	29.66	7	407	6	406	1.0e-43	170	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
651661262	449	54.43	3	448	1	463	0.0e+00	613	COG0215	Cysteinyl-tRNA synthetase	464
651661263	257	42.32	17	257	5	240	8.0e-54	203	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
651661264	186	24.83	37	180	2	140	2.0e-14	72.6	COG2193	Bacterioferritin (cytochrome b1)	157
651661265	167	53.44	37	167	2	132	3.0e-43	167	COG3260	Ni,Fe-hydrogenase III small subunit	148
651661266	466	37.64	106	466	4	367	4.0e-77	282	COG3261	Ni,Fe-hydrogenase III large subunit	382
651661267	482	30.89	8	431	7	428	2.0e-39	157	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
651661268	226	26.89	14	223	7	218	1.0e-14	73.4	COG4237	Hydrogenase-4 membrane subunit HyfE	218
651661269	318	37.26	1	313	1	308	5.0e-42	165	COG0650	Formate hydrogenlyase subunit 4	309
651661270	671	37.25	1	489	1	477	5.0e-59	222	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
651661272	1089	25.94	8	1083	1	1008	0.0e+00	537	COG0841	Multidrug efflux pump subunit AcrB	1009
651661273	336	25.37	6	334	19	352	2.0e-13	70.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
651661274	120	37.61	5	110	2	110	8.0e-14	69.2	COG0607	Rhodanese-related sulfurtransferase	110
651661275	140	34.95	23	124	1	103	3.0e-10	57.5	COG0640	DNA-binding transcriptional regulator, ArsR family	110
651661276	435	25	1	402	3	387	5.0e-30	125	COG1252	NADH dehydrogenase, FAD-containing subunit	405
651661279	131	23.97	5	125	11	124	7.0e-07	46.4	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
651661280	102	42.68	16	97	1	78	5.0e-13	66.2	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
651661287	363	31.34	117	332	9	207	1.0e-36	147	COG0543	NAD(P)H-flavin reductase	252
651661290	344	27.24	36	326	1	291	8.0e-33	134	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
651661291	544	35.53	1	528	2	521	8.0e-87	314	COG0459	Chaperonin GroEL (HSP60 family)	524
651661292	686	35.99	55	683	17	606	4.0e-104	372	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
651661299	294	33.33	26	213	2	190	8.0e-28	117	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
651661300	942	43.95	10	942	2	930	0.0e+00	1061	COG0060	Isoleucyl-tRNA synthetase	933
651661301	177	39.75	5	162	3	161	6.0e-30	123	COG0597	Lipoprotein signal peptidase	167
651661303	409	27.6	10	392	1	379	5.0e-17	82.6	COG2814	Predicted arabinose efflux permease, MFS family	394
651661304	582	42.66	1	580	1	637	0.0e+00	551	COG0323	DNA mismatch repair ATPase MutL	638
651661308	581	22.67	41	193	54	224	2.0e-10	61.4	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
651661309	292	25.26	77	253	25	208	1.0e-12	67.6	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
651661310	469	51.82	136	461	3	332	3.0e-105	375	COG3800	Predicted transcriptional regulator	332
651661312	180	46.29	5	179	1	173	1.0e-47	182	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
651661313	151	46	1	150	1	140	2.0e-34	138	COG5319	Uncharacterized protein	142
651661314	64	46.67	1	59	21	80	2.0e-13	67.7	COG0695	Glutaredoxin	80
651661315	241	41.85	9	235	5	223	5.0e-41	161	COG1040	Predicted amidophosphoribosyltransferases	225
651661317	255	39.63	39	255	8	224	3.0e-57	215	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
651661318	261	50.2	8	255	1	251	2.0e-93	335	COG0024	Methionine aminopeptidase	255
651661319	409	24.02	26	407	16	394	4.0e-18	86	COG2814	Predicted arabinose efflux permease, MFS family	394
651661320	149	25.2	23	149	11	109	2.0e-10	58.8	COG0607	Rhodanese-related sulfurtransferase	110
651661321	335	51.76	9	316	1	300	1.0e-96	346	COG0031	Cysteine synthase	300
651661322	241	44.74	14	240	1	219	8.0e-48	183	COG4340	Uncharacterized protein	226
651661323	786	30.7	466	777	10	316	1.0e-31	131	COG0668	Small-conductance mechanosensitive channel	316
651661324	235	23.41	1	202	1	201	4.0e-16	78.4	COG1011	FMN phosphatase YigB, HAD superfamily	229
651661325	321	47.08	8	320	5	329	7.0e-77	280	COG0240	Glycerol-3-phosphate dehydrogenase	329
651661326	273	45.69	1	259	1	267	8.0e-82	297	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
651661327	615	36.49	31	614	11	593	0.0e+00	504	COG1164	Oligoendopeptidase F	598
651661328	452	29.93	11	418	21	422	2.0e-74	273	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
651661330	133	43.26	2	133	47	187	1.0e-29	121	COG0742	16S rRNA G966 N2-methylase RsmD	187
651661331	247	38.33	9	240	1	240	9.0e-57	213	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
651661332	206	48.8	2	206	33	239	3.0e-53	201	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
651661333	151	51.08	1	139	12	150	1.0e-39	155	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
651661334	517	28.92	4	514	15	545	2.0e-81	297	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
651661335	336	38.41	8	332	10	337	4.0e-66	245	COG1536	Flagellar motor switch protein FliG	339
651661338	691	47.06	19	691	18	693	0.0e+00	716	COG1298	Flagellar biosynthesis pathway, component FlhA	696
651661340	247	29.84	2	247	5	241	5.0e-28	118	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
651661341	320	47.52	15	310	1	300	1.0e-80	293	COG4974	Site-specific recombinase XerD	300
651661342	536	49.04	172	533	2	357	3.0e-111	396	COG0337	3-dehydroquinate synthetase	360
651661344	179	33.71	1	177	4	181	1.0e-25	109	COG3038	Cytochrome b561	181
651661345	275	45.56	6	273	1	266	1.0e-82	300	COG1692	Calcineurin-like phosphoesterase	266
651661346	457	41.96	10	455	3	456	8.0e-83	301	COG0277	FAD/FMN-containing dehydrogenase	459
651661347	154	24.44	2	134	5	137	6.0e-16	76.8	COG0848	Biopolymer transport protein ExbD	137
651661348	223	26.74	16	201	22	208	1.0e-21	96.6	COG0811	Biopolymer transport protein ExbB/TolQ	216
651661349	350	47.69	1	322	1	311	2.0e-82	299	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
651661350	474	23.99	19	460	6	391	9.0e-14	71.8	COG2814	Predicted arabinose efflux permease, MFS family	394
651661351	113	48.18	1	110	21	130	6.0e-35	139	COG1607	Acyl-CoA hydrolase	157
651661353	1157	28.21	9	1141	6	1139	0.0e+00	532	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
651661354	955	35.12	4	679	6	697	2.0e-73	271	COG3893	Inactivated superfamily I helicase	697
651661355	149	38.93	4	149	1	147	2.0e-28	118	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
651661356	339	30.72	8	323	5	304	3.0e-46	179	COG0492	Thioredoxin reductase	305
651661357	256	46.9	1	255	2	257	5.0e-60	224	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
651661358	358	31.36	9	288	16	299	1.0e-54	207	COG0863	DNA modification methylase	302
651661359	302	43.67	5	302	2	290	1.0e-69	257	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
651661360	185	47.78	1	179	8	185	4.0e-58	217	COG0194	Guanylate kinase	191
651661362	509	23.12	1	499	2	491	2.0e-36	147	COG0591	Na+/proline symporter	493
651661363	397	25.07	18	378	31	382	8.0e-15	75.2	COG2814	Predicted arabinose efflux permease, MFS family	394
651661364	260	46.86	1	234	8	243	3.0e-58	218	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
651661365	141	32.33	1	131	3	133	2.0e-06	45	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
651661366	324	31.33	3	292	1	296	2.0e-24	106	COG0583	DNA-binding transcriptional regulator, LysR family	297
651661367	369	22.59	41	369	131	439	1.0e-16	81.2	COG3659	Carbohydrate-selective porin OprB	439
651661368	362	22.91	19	336	2	314	2.0e-15	77.5	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651661369	354	38.02	25	336	4	313	5.0e-43	168	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651661372	364	58.71	1	364	1	372	0.0e+00	480	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
651661373	192	49.19	1	184	2	186	2.0e-64	238	COG0193	Peptidyl-tRNA hydrolase	190
651661374	217	40.22	6	97	3	93	2.0e-16	79.5	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
651661375	263	65.27	27	263	5	243	5.0e-104	370	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
651661376	323	24.29	175	312	46	173	1.0e-06	48	COG1934	Lipopolysaccharide export system protein LptA	173
651661377	246	22.33	22	234	6	215	2.0e-14	73.1	COG5375	Uncharacterized protein	216
651661378	334	55	19	216	2	201	2.0e-59	222	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
651661381	316	35.02	9	265	5	250	6.0e-22	98.4	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
651661382	485	44.69	25	476	1	457	8.0e-126	444	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
651661383	1512	57.38	717	1201	1	482	0.0e+00	624	COG0069	Glutamate synthase domain 2	485
651661384	195	44.74	6	192	1	189	2.0e-48	185	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
651661385	243	54.77	1	240	4	229	4.0e-67	247	COG0689	Ribonuclease PH	230
651661386	367	47.21	28	367	4	341	2.0e-92	332	COG1420	Transcriptional regulator of heat shock response	346
651661387	146	37.84	3	146	15	159	4.0e-22	97.1	COG2030	Acyl dehydratase	159
651661388	345	40.06	7	331	5	321	3.0e-68	252	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
651661389	496	36.16	1	489	3	496	2.0e-88	320	COG1070	Sugar (pentulose or hexulose) kinase	502
651661390	339	32.19	1	337	2	350	3.0e-58	218	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
651661391	449	27.15	13	432	5	427	7.0e-37	148	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
651661392	310	36.52	23	303	8	287	4.0e-51	195	COG1175	ABC-type sugar transport system, permease component	295
651661393	273	40.43	1	273	5	281	2.0e-49	189	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
651661394	361	51.42	1	351	1	338	6.0e-115	407	COG3839	ABC-type sugar transport system, ATPase component	338
651661395	247	41.18	7	245	1	251	5.0e-34	138	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651661396	160	54.23	9	147	4	145	1.0e-39	155	COG0328	Ribonuclease HI	154
651661398	326	41.85	18	326	1	311	5.0e-42	165	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651661399	323	43.77	28	320	14	307	4.0e-39	155	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651661402	456	49.65	171	452	1	262	1.0e-77	284	COG1760	L-serine deaminase	262
651661403	186	36.9	1	184	4	187	7.0e-29	120	COG4583	Sarcosine oxidase gamma subunit	189
651661404	512	40.51	119	512	2	379	3.0e-106	379	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
651661405	159	20	10	158	3	157	8.0e-03	33.2	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
651661406	500	63.12	2	500	10	515	0.0e+00	720	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
651661407	155	40.38	1	154	4	154	7.0e-30	123	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
651661408	373	27.55	18	370	22	379	3.0e-28	119	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651661409	332	41.82	3	331	2	323	2.0e-120	425	COG1087	UDP-glucose 4-epimerase	329
651661410	524	37.24	17	524	39	565	2.0e-88	320	COG5360	Uncharacterized conserved protein, heparinase superfamily	566
651661411	220	56.6	5	216	3	213	5.0e-79	287	COG0036	Pentose-5-phosphate-3-epimerase	220
651661412	161	18.03	24	144	1	119	3.0e-08	51.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
651661413	509	29.98	22	506	21	514	3.0e-59	223	COG0815	Apolipoprotein N-acyltransferase	518
651661414	232	43.96	3	205	2	208	4.0e-55	208	COG4229	Enolase-phosphatase E1 involved in merthionine salvage	229
651661415	187	46.63	8	184	1	172	8.0e-48	183	COG1791	Acireductone dioxygenase (methionine salvage), cupin superfamily	181
651661416	213	32.34	13	212	2	194	4.0e-32	131	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
651661417	85	21.69	1	83	1	81	5.0e-09	52.7	COG1826	Sec-independent protein translocase protein TatA	94
651661418	75	24.32	1	74	1	74	4.0e-11	59.6	COG1826	Sec-independent protein translocase protein TatA	94
651661419	183	47.62	2	182	18	206	3.0e-36	145	COG1584	Succinate-acetate transporter protein	207
651661421	173	33.12	20	173	5	158	6.0e-27	113	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
651661422	125	37.93	9	124	2	113	4.0e-17	80.4	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
651661423	304	24.75	5	299	6	257	1.0e-17	84.2	COG0725	ABC-type molybdate transport system, periplasmic component	258
651661424	238	29.06	2	225	23	256	5.0e-24	104	COG0555	ABC-type sulfate transport system, permease component	274
651661425	185	42.86	1	182	1	173	6.0e-36	143	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
651661427	407	49.6	1	368	28	397	2.0e-113	403	COG0513	Superfamily II DNA and RNA helicase	513
651661430	402	38.52	25	395	18	393	4.0e-60	225	COG4214	ABC-type xylose transport system, permease component	394
651661432	369	41.23	20	356	6	341	2.0e-70	260	COG4213	ABC-type xylose transport system, periplasmic component	341
651661434	623	62.3	94	589	1	495	0.0e+00	645	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
651661436	222	33.99	3	203	2	201	1.0e-27	116	COG0625	Glutathione S-transferase	211
651661437	416	28.25	13	277	4	238	2.0e-33	136	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
651661439	603	33.91	2	403	8	397	1.0e-48	188	COG0475	Kef-type K+ transport system, membrane component KefB	397
651661440	461	37.22	1	442	1	454	5.0e-107	381	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
651661441	468	68.31	11	455	2	444	0.0e+00	703	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
651661442	383	21.88	22	375	17	354	7.0e-19	88.8	COG1488	Nicotinic acid phosphoribosyltransferase	405
651661443	115	29.91	1	107	20	124	2.0e-09	54.2	COG3753	Uncharacterized conserved protein YidB, DUF937 family	143
651661445	583	37.59	291	571	2	268	3.0e-68	253	COG0171	NH3-dependent NAD+ synthetase	268
651661447	89	39.33	1	89	2	90	2.0e-12	64	COG0776	Bacterial nucleoid DNA-binding protein	94
651661450	87	51.19	1	83	1	84	2.0e-20	90.7	COG0851	Septum formation topological specificity factor MinE	88
651661451	271	62.73	1	269	1	270	3.0e-111	394	COG2894	Septum formation inhibitor-activating ATPase MinD	272
651661452	245	37.29	11	244	1	217	4.0e-45	175	COG0850	Septum formation inhibitor MinC	219
651661453	326	31.96	1	315	1	337	8.0e-33	134	COG0673	Predicted dehydrogenase	342
651661454	526	43.37	1	525	1	506	9.0e-119	420	COG0342	Preprotein translocase subunit SecD	506
651661455	326	43.28	10	314	2	304	1.0e-76	280	COG0341	Preprotein translocase subunit SecF	305
651661457	224	27.54	36	224	11	213	2.0e-08	53	COG2755	Lysophospholipase L1 or related esterase	216
651661458	367	29.48	7	356	22	372	1.0e-32	133	COG4645	Uncharacterized protein	410
651661459	196	49.23	1	193	2	196	7.0e-61	226	COG0353	Recombinational DNA repair protein RecR	198
651661460	107	55.77	1	104	4	105	1.0e-23	101	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
651661461	614	42.59	42	507	2	478	3.0e-120	426	COG2812	DNA polymerase III, gamma/tau subunits	515
651661462	303	43.16	17	300	1	267	5.0e-63	234	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
651661463	199	43.9	1	197	3	205	1.0e-43	169	COG0655	Multimeric flavodoxin WrbA	207
651661469	384	44.65	8	383	9	390	1.0e-109	390	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
651661472	744	42.57	3	732	2	739	0.0e+00	750	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
651661475	305	32	11	295	6	300	8.0e-53	200	COG2264	Ribosomal protein L11 methylase PrmA	300
651661477	585	29.24	156	542	5	383	1.0e-52	201	COG0006	Xaa-Pro aminopeptidase	384
651661478	217	46.15	1	217	1	221	5.0e-29	121	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
651661479	186	46.11	1	176	17	196	1.0e-45	176	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
651661480	895	64.12	7	893	1	861	0.0e+00	1252	COG1048	Aconitase A	861
651661481	233	36.9	1	227	3	251	3.0e-31	128	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651661482	453	53.94	1	419	1	413	0.0e+00	527	COG1004	UDP-glucose 6-dehydrogenase	414
651661483	209	40.76	14	193	5	187	2.0e-32	132	COG0406	Broad specificity phosphatase PhoE	208
651661485	602	38.1	8	587	6	563	9.0e-121	427	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
651661486	399	27.51	1	387	1	368	2.0e-25	110	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651661487	454	31.53	142	422	86	374	1.0e-33	137	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651661488	474	35.16	71	470	12	399	4.0e-75	275	COG4671	Predicted glycosyl transferase	400
651661492	176	38.51	27	174	1	146	8.0e-25	106	COG0071	Molecular chaperone IbpA, HSP20 family	146
651661493	287	38.01	1	281	23	298	1.0e-37	150	COG0501	Zn-dependent protease with chaperone function	302
651661494	237	34.25	6	224	7	210	6.0e-44	170	COG0684	Regulator of RNase E activity RraA	210
651661497	1270	59.41	509	1270	1	769	0.0e+00	885	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
651661499	442	43.32	1	334	28	339	2.0e-58	220	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
651661500	143	40.71	1	140	5	141	9.0e-22	96.1	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
651661501	405	28.11	22	351	10	337	3.0e-31	129	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
651661503	369	59	2	358	1	358	0.0e+00	511	COG0082	Chorismate synthase	369
651661504	621	61.18	8	431	2	426	0.0e+00	627	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
651661505	308	33.44	3	308	7	261	2.0e-53	202	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
651661506	508	43.77	26	384	4	340	7.0e-70	258	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
651661509	169	38.51	22	168	6	152	2.0e-32	131	COG1522	DNA-binding transcriptional regulator, Lrp family	154
651661510	179	46.47	6	173	1	169	5.0e-48	183	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
651661511	266	40.31	8	263	17	268	5.0e-53	201	COG3752	Steroid 5-alpha reductase family enzyme	272
651661512	341	27.27	45	337	1	283	5.0e-65	241	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
651661516	230	30.94	1	218	19	239	2.0e-44	172	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
651661517	141	28.71	18	118	1	99	2.0e-10	58.3	COG0640	DNA-binding transcriptional regulator, ArsR family	110
651661518	140	43.1	1	116	1	116	3.0e-37	147	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
651661519	438	39.63	1	428	4	424	6.0e-79	288	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
651661522	791	19.62	137	641	186	675	3.0e-22	101	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
651661523	371	25.31	141	361	51	291	5.0e-13	69.1	COG4974	Site-specific recombinase XerD	300
651661525	254	39.66	24	249	3	228	1.0e-47	183	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
651661526	415	57.59	224	414	5	193	7.0e-61	228	COG0807	GTP cyclohydrolase II	193
651661528	113	21.98	1	91	25	112	3.0e-07	47.2	COG2919	Cell division protein FtsB	117
651661529	319	50.46	1	319	24	345	3.0e-112	398	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
651661532	313	29.45	8	311	4	310	5.0e-32	131	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651661533	312	34.2	1	306	1	305	6.0e-35	141	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651661534	316	54.43	1	315	115	430	5.0e-120	424	COG0104	Adenylosuccinate synthase	430
651661536	1018	29.74	4	1014	1	1008	0.0e+00	561	COG0841	Multidrug efflux pump subunit AcrB	1009
651661538	290	49.05	74	282	3	212	4.0e-47	182	COG0560	Phosphoserine phosphatase	212
651661539	141	50	3	139	1	138	1.0e-40	158	COG1832	Predicted CoA-binding protein	140
651661540	529	28.91	12	297	16	305	2.0e-44	174	COG5309	Exo-beta-1,3-glucanase,  GH17 family	305
651661542	177	24.79	56	176	37	157	8.0e-06	43.5	COG5490	Uncharacterized protein	158
651661543	106	46.43	23	106	24	107	1.0e-25	108	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
651661544	155	25.32	1	140	6	159	2.0e-12	65.4	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
651661545	68	64.71	1	68	1	67	2.0e-22	97.5	COG1278	Cold shock protein, CspA family	67
651661547	411	44.89	37	379	3	354	4.0e-71	262	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
651661548	308	27	40	275	20	239	2.0e-20	93.2	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
651661549	333	24.83	42	322	10	307	4.0e-15	75.6	COG3391	DNA-binding beta-propeller fold protein YncE	381
651661552	254	30.68	9	254	19	281	5.0e-16	78.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
651661553	137	44.37	1	135	2	152	7.0e-39	152	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
651661554	97	32.97	1	89	1	91	1.0e-15	74.6	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
651661555	270	37.55	25	268	34	278	2.0e-36	145	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
651661556	173	41.1	1	146	1	143	7.0e-34	136	COG2332	Cytochrome c-type biogenesis protein CcmE	153
651661557	657	47.38	1	644	1	646	0.0e+00	520	COG1138	Cytochrome c biogenesis factor	648
651661558	184	22.22	42	163	5	127	4.0e-09	54.5	COG0526	Thiol-disulfide isomerase or thioredoxin	127
651661559	163	38.78	18	163	10	151	4.0e-31	127	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
651661560	258	31.56	1	236	2	241	2.0e-14	73.4	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
651661561	606	29.34	47	469	25	443	2.0e-61	230	COG0038	H+/Cl- antiporter ClcA	443
651661562	508	26.31	1	508	2	530	2.0e-68	253	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
651661564	203	29.93	53	199	43	186	7.0e-17	80.7	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
651661566	286	41.79	86	285	1	196	2.0e-32	132	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
651661567	319	42.59	1	319	1	322	6.0e-77	280	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
651661568	427	53.15	1	427	11	437	0.0e+00	491	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
651661569	153	35.54	23	138	13	132	5.0e-17	80.5	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
651661570	265	27.2	9	257	2	250	8.0e-10	57.7	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
651661572	437	37.5	3	409	26	421	3.0e-71	262	COG4964	Flp pilus assembly protein, secretin CpaC	455
651661573	412	30.21	20	353	1	331	5.0e-31	129	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
651661574	291	33	1	291	4	293	5.0e-31	128	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
651661575	306	33.12	8	304	6	312	2.0e-24	106	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
651661576	490	31.75	1	472	2	479	3.0e-78	286	COG1129	ABC-type sugar transport system, ATPase component	500
651661578	176	22.22	10	168	6	164	1.0e-03	36.2	COG3652	Predicted outer membrane protein	170
651661582	315	39.31	1	315	9	325	4.0e-70	258	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
651661583	260	37.93	3	257	2	250	5.0e-39	154	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651661584	245	73.47	1	245	1	245	5.0e-111	393	COG4689	Acetoacetate decarboxylase	247
651661585	354	22.51	1	335	16	306	3.0e-30	126	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
651661586	612	31.11	1	594	1	581	5.0e-99	355	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
651661589	313	32.41	22	309	5	281	6.0e-49	188	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
651661590	332	41.34	1	327	3	330	5.0e-81	294	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
651661591	496	41.72	10	490	7	493	4.0e-109	388	COG1070	Sugar (pentulose or hexulose) kinase	502
651661592	365	29.34	35	365	1	321	3.0e-33	136	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651661593	501	44.2	12	498	9	495	0.0e+00	462	COG1129	ABC-type sugar transport system, ATPase component	500
651661594	336	41.14	14	327	2	314	1.0e-49	190	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651661595	89	38.2	1	89	2	90	7.0e-13	65.5	COG0776	Bacterial nucleoid DNA-binding protein	94
651661596	298	31.49	6	295	2	302	7.0e-36	144	COG0451	Nucleoside-diphosphate-sugar epimerase	314
651661597	327	58.14	1	324	2	345	0.0e+00	497	COG1089	GDP-D-mannose dehydratase	345
651661598	748	38.09	13	744	7	728	5.0e-126	445	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
651661599	347	39.82	1	328	1	282	2.0e-51	196	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
651661600	165	62.58	4	157	3	155	3.0e-54	204	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
651661601	201	20.73	12	173	5	168	3.0e-06	45.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
651661602	225	33.33	6	220	5	219	2.0e-32	132	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
651661603	302	27.11	14	283	1	262	2.0e-11	63.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
651661604	204	31.79	1	165	8	180	4.0e-25	107	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
651661608	146	25.52	2	146	34	176	2.0e-22	98.5	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
651661610	221	47.98	1	220	7	229	2.0e-55	209	COG0571	dsRNA-specific ribonuclease	235
651661612	410	42.66	44	407	16	382	1.0e-83	304	COG1686	D-alanyl-D-alanine carboxypeptidase	389
651661613	86	47.44	12	86	21	97	6.0e-08	49.2	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
651661614	695	58.93	4	693	5	690	0.0e+00	917	COG0480	Translation elongation factor EF-G, a GTPase	697
651661616	284	27.72	41	237	41	216	3.0e-18	85.7	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
651661618	389	31.58	22	386	67	463	2.0e-57	216	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
651661619	392	44.27	10	392	4	377	3.0e-99	355	COG1454	Alcohol dehydrogenase, class IV	377
651661620	194	40	8	154	5	164	9.0e-29	120	COG0406	Broad specificity phosphatase PhoE	208
651661621	206	34.76	1	204	1	206	7.0e-25	107	COG0625	Glutathione S-transferase	211
651661622	310	58.2	1	310	5	314	5.0e-115	407	COG0462	Phosphoribosylpyrophosphate synthetase	314
651661623	167	27.34	23	158	18	150	1.0e-04	39.7	COG1714	Uncharacterized membrane protein YckC, RDD family	172
651661624	233	43.69	2	218	32	253	9.0e-60	223	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
651661625	196	23.58	25	142	6	118	1.0e-03	36.9	COG3794	Plastocyanin	128
651661626	368	23.05	65	368	1	303	1.0e-14	74.5	COG0668	Small-conductance mechanosensitive channel	316
651661627	383	54.35	10	374	5	369	7.0e-118	417	COG0263	Glutamate 5-kinase	369
651661628	332	57.44	1	331	1	336	4.0e-130	457	COG0536	GTPase involved in cell partioning and DNA repair	369
651661629	89	66.67	1	87	1	87	7.0e-30	121	COG0211	Ribosomal protein L27	87
651661630	104	53.4	1	103	1	103	7.0e-31	125	COG0261	Ribosomal protein L21	103
651661635	1089	24.94	19	408	16	381	1.0e-30	129	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651661636	322	47.12	1	208	5	211	1.0e-57	217	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
651661637	117	35.71	1	110	10	118	3.0e-20	90.6	COG0858	Ribosome-binding factor A	118
651661638	643	60.67	140	642	1	504	0.0e+00	642	COG0532	Translation initiation factor IF-2, a GTPase	509
651661640	627	46.71	1	620	3	605	0.0e+00	601	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
651661646	1110	34.19	24	532	1	505	3.0e-91	330	COG0366	Glycosidase	505
651661647	721	57.75	94	719	1	628	0.0e+00	758	COG0296	1,4-alpha-glucan branching enzyme	628
651661648	703	48.93	4	697	8	692	0.0e+00	762	COG1523	Pullulanase/glycogen debranching enzyme	697
651661649	658	34.59	146	652	12	517	7.0e-105	375	COG1640	4-alpha-glucanotransferase	520
651661652	1141	40.96	295	1141	3	842	0.0e+00	822	COG1410	Methionine synthase I, cobalamin-binding domain	842
651661654	133	40.62	3	129	1	127	1.0e-21	95.1	COG3791	Uncharacterized conserved protein	133
651661655	236	24.2	24	236	1	215	7.0e-08	51.1	COG2202	PAS domain	232
651661656	330	39.92	6	267	2	261	5.0e-65	241	COG1131	ABC-type multidrug transport system, ATPase component	293
651661657	350	28.12	2	287	7	287	2.0e-34	140	COG1566	Multidrug resistance efflux pump	352
651661658	324	28.33	30	320	1	297	1.0e-25	110	COG0583	DNA-binding transcriptional regulator, LysR family	297
651661659	499	42.15	5	486	1	472	5.0e-126	444	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
651661660	182	38.59	1	177	1	179	7.0e-30	123	COG1514	2'-5' RNA ligase	180
651661661	316	29.23	1	305	1	337	4.0e-62	231	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
651661662	166	34.94	1	166	5	154	1.0e-33	135	COG1952	Preprotein translocase subunit SecB	157
651661663	467	31.67	1	435	1	394	2.0e-85	309	COG0498	Threonine synthase	411
651661664	417	40.48	1	407	17	436	4.0e-91	328	COG0612	Predicted Zn-dependent peptidase	438
651661666	206	49.47	19	198	9	193	2.0e-44	172	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
651661667	256	27.09	4	254	9	253	1.0e-04	40.8	COG0730	Uncharacterized membrane protein YfcA	258
651661669	390	48.14	1	390	1	391	1.0e-87	316	COG0183	Acetyl-CoA acetyltransferase	392
651661670	233	58.8	1	216	1	215	7.0e-80	290	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
651661671	226	63.06	3	223	6	225	1.0e-80	292	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
651661672	426	51.73	1	425	15	444	0.0e+00	500	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
651661674	92	44.57	1	89	23	114	2.0e-14	71	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
651661676	284	43.26	1	282	8	285	6.0e-73	267	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
651661677	418	39.9	3	391	5	396	7.0e-109	387	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
651661678	116	57.41	1	107	3	110	5.0e-42	162	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
651661679	123	44.04	16	123	2	110	7.0e-30	122	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
651661680	111	47.62	9	111	7	111	2.0e-25	107	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
651661681	151	28.67	9	150	5	147	4.0e-22	97.4	COG0822	NifU homolog involved in Fe-S cluster formation	150
651661682	414	52.22	9	410	2	404	1.0e-123	436	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
651661686	568	26.55	37	567	117	773	2.0e-70	260	COG4993	Glucose dehydrogenase	773
651661688	400	25.58	4	386	18	363	2.0e-08	53.6	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
651661689	405	24.57	98	366	6	287	4.0e-15	76.4	COG4974	Site-specific recombinase XerD	300
651661695	599	32.39	39	457	11	388	7.0e-58	218	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
651661696	212	26.88	1	186	6	177	1.0e-07	49.6	COG3226	DNA-binding transcriptional regulator YbjK	204
651661698	705	39.56	247	680	3	454	3.0e-104	373	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
651661699	211	32.81	10	190	7	197	2.0e-15	75.8	COG3222	Uncharacterized conserved protein, glycosyltransferase A (GT-A) superfamily, DUF2064 family	211
651661700	305	33.11	1	302	1	303	4.0e-59	222	COG1893	Ketopantoate reductase	307
651661701	146	31.62	12	146	6	139	1.0e-18	85.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
651661702	564	61	226	563	1	339	1.0e-96	347	COG1299	Phosphotransferase system, fructose-specific IIC component	343
651661703	317	44.19	4	311	2	308	7.0e-77	280	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
651661704	837	48.06	276	831	3	565	0.0e+00	580	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
651661705	335	40.96	3	328	1	332	4.0e-81	294	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
651661706	761	30.23	22	583	106	652	3.0e-100	360	COG0209	Ribonucleotide reductase alpha subunit	696
651661707	296	27.15	45	262	33	251	1.0e-12	67	COG5607	CHAD domain (function unknown)	283
651661708	431	26.82	47	430	1	371	2.0e-23	103	COG3174	Uncharacterized membrane protein, DUF4010 family	371
651661709	357	49.02	1	355	1	348	3.0e-116	411	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
651661710	331	55.62	4	331	3	330	0.0e+00	478	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
651661711	91	58.11	18	91	11	84	1.0e-16	78	COG3750	Uncharacterized conserved protein, UPF0335 family	85
651661712	104	69.79	9	104	9	104	2.0e-33	133	COG3492	Uncharacterized protein	104
651661713	474	47.69	6	474	2	477	0.0e+00	545	COG0469	Pyruvate kinase	477
651661716	255	26.27	4	250	3	248	1.0e-21	97.1	COG2365	Protein tyrosine/serine phosphatase	249
651661717	347	24.79	3	346	100	453	3.0e-34	139	COG2211	Na+/melibiose symporter or related transporter	467
651661719	463	54.7	1	453	1	454	0.0e+00	528	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
651661720	410	50.48	1	409	1	404	5.0e-113	401	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
651661721	949	54.21	13	949	12	906	0.0e+00	1229	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
651661722	291	64.48	1	290	1	290	5.0e-115	407	COG0074	Succinyl-CoA synthetase, alpha subunit	293
651661723	398	60.15	1	397	1	387	0.0e+00	512	COG0045	Succinyl-CoA synthetase, beta subunit	387
651661724	384	44.47	13	383	11	367	1.0e-103	369	COG1485	Predicted ATPase	367
651661729	277	38.52	15	270	1	253	1.0e-51	196	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
651661730	328	37.2	1	328	3	326	7.0e-68	250	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
651661732	479	56.99	1	475	11	488	0.0e+00	683	COG0753	Catalase	496
651661733	462	26.46	16	453	4	436	6.0e-40	158	COG1457	Purine-cytosine permease or related protein	442
651661734	180	49.11	1	165	1	168	9.0e-34	136	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
651661735	399	43.52	1	399	1	405	6.0e-107	381	COG3748	Uncharacterized membrane protein	407
651661736	116	45.69	1	115	8	123	3.0e-30	123	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
651661737	261	29.44	10	239	47	266	4.0e-23	101	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
651661738	812	59.08	31	811	6	780	0.0e+00	1039	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
651661739	518	49.9	1	500	4	483	0.0e+00	507	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
651661740	306	37.92	6	297	1	293	7.0e-30	124	COG0583	DNA-binding transcriptional regulator, LysR family	297
651661741	591	76.78	1	590	4	590	0.0e+00	990	COG3960	Glyoxylate carboligase	592
651661742	268	58.89	1	253	1	253	1.0e-98	353	COG3622	Hydroxypyruvate isomerase	260
651661743	292	50.7	1	284	1	286	5.0e-80	291	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
651661744	439	55.85	17	433	8	422	2.0e-128	452	COG2379	Glycerate-2-kinase	422
651661745	431	26.7	46	417	31	406	1.0e-31	131	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
651661746	414	34.31	21	414	12	408	1.0e-50	194	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
651661747	307	26.49	4	299	3	267	4.0e-28	118	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
651661748	307	27.33	9	307	2	291	9.0e-27	114	COG0583	DNA-binding transcriptional regulator, LysR family	297
651661750	281	48.06	4	274	3	282	1.0e-71	263	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
651661751	302	38.41	31	297	1	284	4.0e-45	175	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
651661753	464	29.5	134	452	21	335	5.0e-34	139	COG0642	Signal transduction histidine kinase	336
651661754	223	43.61	1	222	5	229	1.0e-58	219	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
651661756	299	45.96	1	276	3	286	4.0e-79	288	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
651661757	137	36.97	2	117	5	123	8.0e-24	103	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
651661758	99	55.17	12	98	2	88	5.0e-21	92.6	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
651661759	256	38.66	23	256	17	231	2.0e-29	122	COG0670	Integral membrane protein, interacts with FtsH	233
651661760	89	67.42	1	89	1	89	1.0e-26	111	COG0184	Ribosomal protein S15P/S13E	89
651661761	311	37.94	5	311	2	269	7.0e-59	220	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
651661762	295	39.72	4	289	1	279	4.0e-69	254	COG0287	Prephenate dehydrogenase	279
651661763	338	42.34	4	333	24	351	2.0e-81	296	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
651661764	295	30.77	10	97	2	92	3.0e-09	56.1	COG1605	Chorismate mutase	101
651661765	381	54.04	16	374	21	368	5.0e-123	434	COG2021	Homoserine acetyltransferase	368
651661767	245	40.61	1	226	2	230	4.0e-57	214	COG1131	ABC-type multidrug transport system, ATPase component	293
651661769	209	28.06	7	198	1	192	1.0e-24	106	COG0406	Broad specificity phosphatase PhoE	208
651661770	242	29.49	20	233	3	215	5.0e-27	114	COG2930	Lipid-binding SYLF domain	227
651661771	158	58.39	1	149	3	151	8.0e-51	192	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
651661772	241	29.78	16	240	4	223	1.0e-34	140	COG1451	Predicted metal-dependent hydrolase	223
651661773	335	34.02	1	333	1	325	1.0e-57	217	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
651661774	197	39.39	1	197	3	192	1.0e-44	173	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
651661775	117	36.78	1	87	10	96	6.0e-10	56.2	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
651661776	326	32.01	1	323	2	313	7.0e-38	151	COG0451	Nucleoside-diphosphate-sugar epimerase	314
651661777	276	35.64	1	276	2	286	2.0e-57	215	COG0682	Prolipoprotein diacylglyceryltransferase	287
651661778	324	37.69	16	324	35	369	2.0e-63	235	COG1565	SAM-dependent methyltransferase, MidA family	370
651661779	247	41.49	7	243	10	245	6.0e-56	210	COG1496	Copper oxidase (laccase) domain	249
651661781	634	45.71	12	617	1	581	0.0e+00	612	COG0322	Excinuclease UvrABC, nuclease subunit	581
651661782	463	37.47	5	456	4	485	5.0e-108	385	COG0260	Leucyl aminopeptidase	485
651661784	206	23.24	27	201	18	201	2.0e-20	92.4	COG2834	Outer membrane lipoprotein-sorting protein	211
651661785	251	44.18	5	251	2	242	5.0e-64	237	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
651661786	227	42.37	1	225	28	261	1.0e-59	222	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
651661787	267	36.06	6	267	3	261	1.0e-64	240	COG0708	Exonuclease III	261
651661789	156	67.31	1	156	18	173	1.0e-56	211	COG0290	Translation initiation factor IF-3	176
651661790	255	49.6	1	250	1	247	7.0e-80	290	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
651661791	301	51.47	1	298	2	307	7.0e-96	344	COG0223	Methionyl-tRNA formyltransferase	307
651661792	188	50.9	15	179	3	168	9.0e-50	190	COG0242	Peptide deformylase	168
651661793	167	33.1	1	134	6	146	7.0e-21	93.5	COG0071	Molecular chaperone IbpA, HSP20 family	146
651661794	85	28.21	22	85	8	85	5.0e-06	42.6	COG5568	Uncharacterized protein	85
651661795	225	57.23	48	219	1	170	4.0e-71	260	COG0225	Peptide methionine sulfoxide reductase MsrA	174
651661796	493	52.88	16	479	1	459	0.0e+00	619	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
651661797	187	27.56	1	156	1	155	3.0e-16	78.4	COG1286	Uncharacterized membrane protein, required for colicin V production	182
651661798	451	55.38	1	441	16	453	0.0e+00	545	COG1066	Predicted ATP-dependent serine protease	456
651661800	216	48.75	45	204	5	164	9.0e-41	160	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
651661801	201	27.55	16	201	64	242	5.0e-17	81.4	COG1651	Protein-disulfide isomerase	244
651661805	251	41.08	14	251	16	246	3.0e-37	148	COG0356	FoF1-type ATP synthase, membrane subunit a	246
651661806	77	47.46	19	77	19	77	3.0e-03	33.3	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
651661807	189	24.83	40	188	9	157	8.0e-12	63.7	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
651661808	173	34.81	9	166	3	160	2.0e-11	62.2	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
651661809	254	53.6	1	249	1	247	6.0e-88	317	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
651661810	79	53.85	1	78	2	79	1.0e-20	91.8	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
651661813	906	49.49	200	590	74	465	5.0e-112	399	COG1530	Ribonuclease G or E	487
651661819	247	38.74	4	245	2	251	1.0e-41	163	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651661820	308	27.59	8	292	6	286	8.0e-31	127	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
651661821	332	37.77	4	315	2	324	1.0e-78	286	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
651661822	567	42.75	23	562	28	574	0.0e+00	547	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
651661823	240	29.49	7	223	3	205	4.0e-27	114	COG0684	Regulator of RNase E activity RraA	210
651661824	149	46.94	4	149	2	148	2.0e-38	151	COG1981	Uncharacterized membrane protein	149
651661825	230	31.53	5	225	2	218	1.0e-30	126	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
651661826	362	35.8	11	331	5	320	1.0e-84	306	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
651661827	358	45.87	1	347	1	350	3.0e-91	328	COG0407	Uroporphyrinogen-III decarboxylase	352
651661828	288	44.07	8	274	6	266	5.0e-75	274	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
651661829	660	30.38	23	553	16	597	2.0e-95	343	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
651661830	487	42.46	28	487	11	473	1.0e-100	360	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
651661831	451	43.52	4	450	2	451	1.0e-100	360	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
651661832	362	44.13	20	362	1	316	4.0e-57	215	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
651661833	461	41.54	12	455	5	446	3.0e-99	355	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
651661834	387	35.66	14	373	8	378	1.0e-58	220	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
651661835	364	35.26	4	361	2	357	6.0e-68	251	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
651661836	479	50.21	4	466	3	459	0.0e+00	560	COG0773	UDP-N-acetylmuramate-alanine ligase	459
651661839	497	37.59	58	494	68	493	1.0e-102	367	COG3517	Predicted component of the type VI protein secretion system	495
651661840	497	53.69	1	497	1	494	0.0e+00	678	COG3517	Predicted component of the type VI protein secretion system	495
651661841	152	54.05	2	149	17	164	2.0e-45	174	COG3516	Predicted component of the type VI protein secretion system	169
651661842	271	38.76	15	270	10	265	3.0e-44	172	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion	273
651661843	173	36.05	21	167	10	153	2.0e-17	81.9	COG3518	Predicted component of the type VI protein secretion system	157
651661844	605	41.53	1	605	1	621	0.0e+00	498	COG3519	Type VI protein secretion system component VasA	621
651661845	353	34.15	4	323	14	325	4.0e-46	178	COG3520	Predicted component of the type VI protein secretion system	335
651661848	197	23.89	22	196	28	207	1.0e-13	69.9	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
651661849	232	30.41	12	222	6	216	6.0e-22	97.7	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
651661850	218	28.9	8	175	11	181	3.0e-13	68.7	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
651661851	308	25.41	1	306	4	297	6.0e-23	101	COG2177	Cell division protein FtsX	297
651661852	223	49.32	1	219	1	215	3.0e-71	261	COG2884	ABC-type ATPase involved in cell division	223
651661854	349	35.71	11	328	3	311	3.0e-63	235	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
651661855	606	45.78	9	602	7	619	0.0e+00	641	COG0326	Molecular chaperone, HSP90 family	623
651661857	224	19.02	10	193	6	169	1.0e-04	40.4	COG3637	Opacity protein and related surface antigens	199
651661860	162	55.24	59	161	16	118	1.0e-25	109	COG3761	NADH:ubiquinone oxidoreductase 17.2 kD subunit	118
651661862	258	29.76	3	85	9	90	2.0e-09	56.1	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
651661863	338	28.12	32	322	1	291	2.0e-32	133	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
651661864	347	37.78	1	347	4	337	2.0e-70	259	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
651661866	156	25.62	35	155	22	141	4.0e-08	50.9	COG3431	Uncharacterized membrane protein, DUF373 family	142
651661867	312	43.14	15	310	14	310	1.0e-56	213	COG0657	Acetyl esterase/lipase	312
651661868	225	44.59	4	224	1	222	6.0e-69	253	COG1136	ABC-type lipoprotein export system, ATPase component	226
651661869	415	39.95	1	415	1	408	8.0e-95	340	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
651661870	437	42.48	1	435	1	498	0.0e+00	465	COG0442	Prolyl-tRNA synthetase	500
651661871	364	26.12	1	364	9	380	2.0e-17	84.1	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
651661872	548	37.75	5	546	6	555	0.0e+00	515	COG0595	mRNA degradation ribonuclease J1/J2	555
651661873	266	45.67	1	253	1	251	4.0e-64	238	COG1521	Pantothenate kinase type III	251
651661874	242	37.82	13	241	1	235	4.0e-40	158	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
651661875	482	47.27	4	477	1	475	4.0e-97	348	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
651661876	505	50.3	1	494	1	492	0.0e+00	472	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
651661877	642	45.07	3	637	1	606	3.0e-127	449	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
651661878	103	54.46	3	103	1	100	8.0e-19	85.5	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
651661879	216	47.31	1	167	2	163	5.0e-27	114	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
651661880	163	45.78	3	163	1	161	4.0e-44	170	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
651661881	338	54.98	5	334	3	332	3.0e-96	345	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
651661882	686	50.37	1	675	1	679	0.0e+00	714	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
651661883	431	56.5	1	421	5	424	0.0e+00	626	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
651661884	203	45.24	7	167	1	159	2.0e-46	178	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
651661885	406	59.59	21	406	13	398	0.0e+00	598	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
651661886	213	49.06	29	186	21	176	1.0e-40	159	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
651661887	186	62.5	18	185	1	168	5.0e-75	273	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
651661888	121	51.24	1	121	1	121	9.0e-30	122	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
651661891	87	58.14	2	87	6	91	2.0e-21	94	COG0776	Bacterial nucleoid DNA-binding protein	94
651661892	813	67.73	15	791	2	782	0.0e+00	1187	COG0466	ATP-dependent Lon protease, bacterial type	782
651661893	375	70.59	1	372	30	403	0.0e+00	634	COG1219	ATP-dependent protease Clp, ATPase subunit	408
651661894	209	71.28	12	206	2	196	2.0e-82	298	COG0740	ATP-dependent protease ClpP, protease subunit	200
651661895	440	39.73	1	439	1	441	4.0e-92	332	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
651661897	658	26.3	13	319	7	333	1.0e-22	102	COG3240	Phospholipase/lecithinase/hemolysin	370
651661898	938	39.89	68	928	18	862	0.0e+00	712	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
651661901	356	59.12	11	348	5	343	5.0e-127	447	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
651661902	361	30.86	9	358	14	355	4.0e-34	138	COG0628	Predicted PurR-regulated permease PerM	355
651661904	727	52.14	12	706	1	696	0.0e+00	857	COG0855	Polyphosphate kinase	696
651661911	369	40.52	1	369	2	366	1.0e-89	323	COG4091	Predicted homoserine dehydrogenase, contains C-terminal SAF domain	438
651661914	395	30.79	31	384	9	369	5.0e-55	208	COG2821	Membrane-bound lytic murein transglycosylase	373
651661916	630	53.74	2	630	1	627	0.0e+00	743	COG3158	K+ transporter	627
651661920	445	69.76	4	415	16	433	0.0e+00	613	COG2224	Isocitrate lyase	433
651661921	358	42.56	17	347	10	339	8.0e-90	324	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
651661922	150	28.39	12	145	25	179	1.0e-11	62.7	COG5389	Uncharacterized protein	181
651661923	915	52.33	318	915	1	593	0.0e+00	712	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
651661926	184	35.29	3	184	2	181	2.0e-51	195	COG0717	Deoxycytidine triphosphate deaminase	183
651661927	418	62.62	1	418	1	420	0.0e+00	582	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
651661929	186	44.22	4	150	1	147	1.0e-36	146	COG0359	Ribosomal protein L9	148
651661930	273	40.41	27	269	2	244	1.0e-42	166	COG1414	DNA-binding transcriptional regulator, IclR family	246
651661931	148	21.8	6	138	3	133	1.0e-09	56.2	COG1765	Uncharacterized OsmC-related protein	137
651661932	233	48.52	1	233	1	237	6.0e-68	250	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
651661933	235	40	3	235	1	250	4.0e-60	224	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
651661934	302	34.74	3	297	8	311	5.0e-25	108	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
651661935	293	35.12	1	293	3	297	3.0e-37	149	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
651661936	418	24.65	29	377	2	340	5.0e-26	112	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
651661939	512	29.55	174	464	9	265	1.0e-30	127	COG1575	1,4-dihydroxy-2-naphthoate octaprenyltransferase	303
651661940	148	31.16	5	139	3	140	6.0e-18	83.3	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
651661941	131	27.52	20	122	14	122	2.0e-05	41.1	COG3631	Ketosteroid isomerase-related protein	133
651661942	373	58.74	7	354	3	350	0.0e+00	497	COG1740	Ni,Fe-hydrogenase I small subunit	355
651661943	598	57.53	16	598	1	545	0.0e+00	698	COG0374	Ni,Fe-hydrogenase I large subunit	545
651661944	244	50.23	26	240	12	227	1.0e-55	209	COG1969	Ni,Fe-hydrogenase I cytochrome b subunit	227
651661945	174	35.95	6	158	5	157	8.0e-27	113	COG0680	Ni,Fe-hydrogenase maturation factor	160
651661947	257	24.6	9	250	15	264	1.0e-22	100	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
651661948	288	45.49	13	287	6	282	4.0e-56	212	COG4132	ABC-type uncharacterized transport system, permease component	282
651661949	366	30.54	61	353	1	280	2.0e-32	133	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
651661951	125	47.57	18	120	3	105	2.0e-19	88.2	COG2076	Multidrug transporter EmrE and related cation transporters	106
651661952	314	32.67	1	300	3	302	3.0e-65	242	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
651661953	286	53.18	14	280	9	274	2.0e-83	302	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
651661954	417	43.92	6	401	4	386	1.0e-109	390	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
651661955	487	51.57	7	482	2	471	0.0e+00	487	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
651661956	552	53.39	1	536	4	541	0.0e+00	489	COG2303	Choline dehydrogenase or related flavoprotein	542
651661957	417	31.06	29	407	1	387	1.0e-55	210	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
651661958	84	57.69	1	78	1	78	4.0e-26	109	COG4311	Sarcosine oxidase delta subunit	97
651661961	172	54.61	12	163	4	155	6.0e-45	173	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
651661962	517	36.8	4	496	13	523	3.0e-93	335	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
651661963	265	37.4	16	262	6	257	6.0e-44	171	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
651661964	448	29.06	9	433	5	428	2.0e-45	176	COG1457	Purine-cytosine permease or related protein	442
651661968	259	30.14	13	229	1	213	2.0e-36	145	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
651661969	197	28.4	31	195	28	187	3.0e-11	62	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
651661970	414	26.02	26	284	5	245	8.0e-27	115	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
651661972	114	25.86	1	114	20	127	5.0e-03	33.4	COG2010	Cytochrome c, mono- and diheme variants	150
651661973	150	30.77	50	150	44	147	2.0e-11	62	COG5501	Predicted secreted protein	148
651661976	578	25.74	95	545	37	477	5.0e-52	199	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
651661977	145	29.25	41	145	11	112	5.0e-06	43.7	COG1416	Intracellular sulfur oxidation protein, DsrE/DsrF family	112
651661978	261	33.85	1	256	4	256	1.0e-08	53.9	COG0730	Uncharacterized membrane protein YfcA	258
651661981	129	33.01	11	111	19	121	1.0e-14	72.6	COG3439	Uncharacterized conserved protein, DUF302 family	137
651661983	392	44.84	5	392	3	395	5.0e-119	421	COG0282	Acetate kinase	396
651661984	310	30.27	9	187	45	227	1.0e-26	113	COG2114	Adenylate cyclase, class 3	227
651661985	477	45.99	10	476	1	442	0.0e+00	524	COG0174	Glutamine synthetase	443
651661986	158	73.21	47	158	1	112	5.0e-40	156	COG0347	Nitrogen regulatory protein PII	112
651661987	391	36.34	19	388	21	393	2.0e-83	303	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
651661988	284	36.65	6	282	2	263	3.0e-47	182	COG0388	Predicted amidohydrolase	274
651661989	253	28.85	4	252	25	276	5.0e-43	168	COG0061	NAD kinase	281
651661990	175	41.42	2	169	16	182	8.0e-30	123	COG2320	GrpB domain, predicted nucleotidyltransferase, UPF0157 family	185
651661991	327	30.86	6	327	1	312	2.0e-60	226	COG0039	Malate/lactate dehydrogenase	313
651661992	195	23.2	10	186	11	169	3.0e-06	45.3	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
651661994	313	33.78	4	295	3	295	3.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
651661995	161	24.84	1	146	3	153	2.0e-16	78.4	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
651661996	882	40.21	12	882	1	786	0.0e+00	745	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
651661999	476	54.81	103	476	3	364	0.0e+00	512	COG0505	Carbamoylphosphate synthase small subunit	368
651662000	1081	70.13	13	407	1	393	0.0e+00	563	COG0458	Carbamoylphosphate synthase large subunit	400
651662001	157	50.99	6	156	1	150	5.0e-41	160	COG0782	Transcription elongation factor, GreA/GreB family	151
651662002	398	49.27	1	335	6	346	6.0e-87	314	COG1171	Threonine dehydratase	347
651662003	401	40.55	6	399	3	384	2.0e-94	339	COG2309	Leucyl aminopeptidase (aminopeptidase T)	385
651662004	267	25.09	1	264	2	263	6.0e-34	137	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
651662005	257	46.67	1	253	2	254	2.0e-76	279	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
651662006	505	54.22	1	503	2	507	0.0e+00	625	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
651662013	346	17.56	24	297	4	279	1.0e-07	51.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
651662015	362	24.38	21	330	10	319	1.0e-26	114	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
651662016	301	36.95	1	292	6	296	1.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
651662017	390	50.99	1	390	1	403	4.0e-117	414	COG2081	Predicted flavoprotein YhiN	408
651662019	131	30.89	1	119	25	141	2.0e-15	74.6	COG2927	DNA polymerase III, chi subunit	144
651662021	197	35.75	3	189	21	225	2.0e-29	122	COG1407	Metallophosphoesterase superfamily enzyme	235
651662023	415	47.37	1	414	1	400	2.0e-125	442	COG0162	Tyrosyl-tRNA synthetase	401
651662024	145	44.59	1	144	1	140	2.0e-31	128	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
651662025	347	28.67	37	324	4	289	2.0e-23	103	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
651662027	391	19.59	36	377	43	381	9.0e-09	54.8	COG2814	Predicted arabinose efflux permease, MFS family	394
651662028	249	21.15	46	244	2	208	2.0e-05	43.4	COG2755	Lysophospholipase L1 or related esterase	216
651662029	606	33.24	237	606	3	372	1.0e-61	231	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
651662030	349	33.93	11	343	1	325	8.0e-71	260	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
651662031	334	47.04	32	334	11	312	3.0e-97	348	COG3958	Transketolase, C-terminal subunit	312
651662032	298	45.61	22	260	6	243	1.0e-83	302	COG3959	Transketolase, N-terminal subunit	243
651662034	549	34.93	173	547	1	375	2.0e-69	256	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
651662035	249	41.73	1	240	1	251	1.0e-38	153	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651662036	382	45.69	3	381	34	410	4.0e-104	371	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
651662037	256	56.35	3	254	1	252	8.0e-100	356	COG0052	Ribosomal protein S2	252
651662038	301	52.63	1	301	1	296	3.0e-88	318	COG0264	Translation elongation factor EF-Ts	296
651662042	283	33.64	45	255	1	200	3.0e-27	116	COG0625	Glutathione S-transferase	211
651662044	305	41.75	22	305	5	288	1.0e-39	156	COG0382	4-hydroxybenzoate polyprenyltransferase	289
651662045	214	47.85	3	210	8	216	1.0e-48	186	COG3897	Predicted nicotinamide N-methyase	218
651662046	146	47.24	24	145	3	129	1.0e-17	82.7	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
651662047	125	32.48	8	124	1	117	2.0e-16	78.3	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
651662048	600	53.62	11	583	2	561	0.0e+00	626	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
651662049	260	54.47	26	259	1	231	2.0e-83	302	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
651662051	549	31.72	220	548	17	329	7.0e-39	155	COG0642	Signal transduction histidine kinase	336
651662052	233	46.52	5	232	3	227	2.0e-55	209	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
651662053	241	26.81	15	238	6	235	3.0e-18	85.8	COG0748	Putative heme iron utilization protein	245
651662054	541	58.81	15	536	6	525	0.0e+00	731	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
651662055	389	49.74	5	389	5	391	2.0e-116	412	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
651662056	229	28.44	8	218	4	195	2.0e-23	102	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
651662057	182	34.75	19	136	5	122	1.0e-12	66.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
651662058	358	34.81	16	349	7	341	2.0e-60	226	COG1566	Multidrug resistance efflux pump	352
651662059	524	18.88	43	418	36	351	1.0e-15	78.7	COG2814	Predicted arabinose efflux permease, MFS family	394
651662060	213	59.13	7	213	3	210	9.0e-78	283	COG0035	Uracil phosphoribosyltransferase	210
651662062	508	62.58	1	496	4	498	0.0e+00	575	COG2986	Histidine ammonia-lyase	498
651662063	277	46.3	5	274	4	268	1.0e-80	292	COG3741	N-formylglutamate amidohydrolase	272
651662064	556	75.36	1	556	2	557	0.0e+00	965	COG2987	Urocanate hydratase	561
651662065	254	34.03	7	242	1	236	1.0e-47	183	COG2188	DNA-binding transcriptional regulator, GntR family	236
651662066	297	41.2	28	293	11	263	9.0e-58	217	COG3741	N-formylglutamate amidohydrolase	272
651662067	135	36.36	25	134	1	108	4.0e-19	87.2	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
651662069	610	59.77	4	607	3	603	0.0e+00	913	COG1217	Predicted membrane GTPase involved in stress response	603
651662070	274	44.96	1	274	3	278	2.0e-83	302	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
651662072	320	47.06	5	320	1	323	1.0e-91	329	COG0523	GTPase, G3E family	323
651662074	725	42.88	2	718	172	915	0.0e+00	698	COG0474	Magnesium-transporting ATPase (P-type)	917
651662075	132	36.97	1	119	2	120	2.0e-20	91.8	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
651662076	231	50.53	35	221	8	194	8.0e-64	236	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
651662079	165	42.04	9	165	1	157	6.0e-48	183	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
651662080	435	51.1	16	423	19	423	0.0e+00	505	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
651662085	449	20.42	14	394	39	439	2.0e-13	70.8	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
651662087	222	32.88	1	214	3	219	1.0e-41	163	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
651662088	349	42.31	38	349	8	315	4.0e-76	278	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
651662089	520	30.64	1	511	1	502	1.0e-77	284	COG1070	Sugar (pentulose or hexulose) kinase	502
651662090	365	41.13	1	354	2	338	8.0e-91	327	COG3839	ABC-type sugar transport system, ATPase component	338
651662091	362	40.92	1	346	1	338	9.0e-88	317	COG3839	ABC-type sugar transport system, ATPase component	338
651662092	283	36.4	4	282	8	281	1.0e-47	183	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
651662093	308	34.8	12	305	1	295	1.0e-50	193	COG1175	ABC-type sugar transport system, permease component	295
651662094	482	19.87	23	478	1	431	2.0e-29	123	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
651662095	329	42.31	1	309	7	316	4.0e-72	265	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
651662096	423	27.52	8	417	3	445	4.0e-55	209	COG1070	Sugar (pentulose or hexulose) kinase	502
651662097	280	33.2	9	256	1	243	6.0e-46	178	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
651662099	209	31.94	13	200	12	202	5.0e-28	118	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
651662100	310	60.6	3	302	1	300	2.0e-112	398	COG0031	Cysteine synthase	300
651662101	339	65.28	1	337	3	338	0.0e+00	539	COG0059	Ketol-acid reductoisomerase	338
651662102	353	40	4	353	1	375	5.0e-53	201	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
651662103	306	54.82	2	301	84	384	2.0e-107	382	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
651662109	251	28.79	35	229	3	189	2.0e-27	115	COG3271	Predicted double-glycine peptidase	201
651662112	315	38.19	15	260	2	246	1.0e-32	134	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651662113	289	29.58	144	278	1	142	6.0e-15	75.1	COG2030	Acyl dehydratase	159
651662114	285	42.55	5	285	1	273	1.0e-68	253	COG3777	Hydroxyacyl-ACP dehydratase HTD2, hotdog domain	273
651662115	382	44.65	2	376	4	384	1.0e-90	326	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
651662116	399	43.65	18	399	6	393	3.0e-77	282	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
651662117	207	42.19	14	204	9	200	1.0e-33	136	COG2860	Uncharacterized membrane protein YeiH	209
651662119	243	45.27	1	243	4	245	2.0e-78	285	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
651662120	396	30.39	15	384	3	360	6.0e-88	318	COG1932	Phosphoserine aminotransferase	365
651662121	528	50.32	1	309	3	313	6.0e-96	345	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
651662122	387	27.6	1	381	6	371	1.0e-24	107	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
651662123	1049	43.06	1	1028	1	1009	0.0e+00	861	COG0841	Multidrug efflux pump subunit AcrB	1009
651662126	596	36.01	3	595	1	577	0.0e+00	479	COG0018	Arginyl-tRNA synthetase	577
651662127	380	45.41	3	376	9	411	2.0e-95	343	COG0232	dGTP triphosphohydrolase	412
651662128	109	52.88	6	108	7	110	1.0e-31	128	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
651662129	256	44.06	1	256	1	261	7.0e-77	280	COG0708	Exonuclease III	261
651662130	534	41.31	5	534	1	485	0.0e+00	492	COG2509	Uncharacterized FAD-dependent dehydrogenase	486
651662131	505	40.93	3	495	1	528	0.0e+00	466	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
651662133	475	20.35	69	469	50	391	2.0e-11	64.1	COG2814	Predicted arabinose efflux permease, MFS family	394
651662137	376	22.36	57	376	1	316	1.0e-26	114	COG0668	Small-conductance mechanosensitive channel	316
651662139	294	32.75	2	285	12	292	8.0e-36	144	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
651662140	257	38.75	12	249	14	253	2.0e-49	189	COG4705	Uncharacterized membrane-anchored protein	258
651662141	283	46.75	38	283	6	244	4.0e-66	245	COG0020	Undecaprenyl pyrophosphate synthase	245
651662144	349	38.56	40	344	29	324	6.0e-51	194	COG4158	Predicted ABC-type sugar transport system, permease component	329
651662145	329	33.1	6	293	4	293	7.0e-42	164	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651662146	299	41.36	1	191	4	187	2.0e-41	163	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
651662148	249	52.31	1	249	1	260	9.0e-72	263	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
651662149	311	54.11	2	311	1	311	6.0e-82	297	COG2025	Electron transfer flavoprotein, alpha subunit	313
651662150	291	53.17	1	283	1	284	7.0e-95	340	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
651662151	296	22.38	10	294	2	282	1.0e-05	44.1	COG5006	Threonine/homoserine efflux transporter RhtA	292
651662152	446	20.23	282	444	1	170	1.0e-04	41.1	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
651662153	359	23.68	3	317	1	311	9.0e-21	94.5	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
651662154	272	30.53	8	269	3	257	1.0e-32	133	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
651662155	280	42.29	8	260	3	236	2.0e-64	239	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
651662156	189	22.61	1	182	1	197	5.0e-21	94.3	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
651662157	640	52.96	34	640	1	586	0.0e+00	750	COG0441	Threonyl-tRNA synthetase	589
651662159	219	42.23	20	219	48	249	4.0e-51	194	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
651662160	1079	43.96	10	553	2	550	0.0e+00	485	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
651662161	647	29.37	19	457	13	458	4.0e-41	163	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
651662162	196	34.72	12	196	11	201	9.0e-23	100	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
651662163	319	49.05	1	316	1	309	3.0e-87	315	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
651662164	249	49.21	6	247	1	251	5.0e-42	164	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651662165	79	58.97	1	78	3	80	6.0e-13	65.7	COG0236	Acyl carrier protein	80
651662166	422	58.06	2	421	1	411	0.0e+00	476	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
651662167	331	37.09	1	319	7	339	1.0e-76	279	COG1559	Cell division protein YceG, involved in septum cleavage	342
651662168	322	26.22	161	317	22	181	2.0e-08	53.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
651662169	279	45.42	3	279	1	270	3.0e-72	265	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
651662170	371	34.85	1	368	10	405	9.0e-65	240	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
651662172	299	45.29	21	295	5	275	2.0e-79	289	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
651662175	799	15.82	20	773	24	754	1.0e-12	69.2	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
651662176	251	33.52	53	230	42	223	2.0e-07	49.8	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
651662177	330	28.86	31	320	1	292	4.0e-20	92.5	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
651662178	518	26.57	1	514	3	540	3.0e-29	123	COG1178	ABC-type Fe3+ transport system, permease component	540
651662183	242	26	23	222	3	201	6.0e-08	51.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
651662184	507	30.69	21	499	1	456	5.0e-55	209	COG1538	Outer membrane protein TolC	457
651662185	394	27.93	23	377	1	367	7.0e-32	131	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
651662186	1020	38.68	3	1007	1	1006	0.0e+00	815	COG0841	Multidrug efflux pump subunit AcrB	1009
651662187	137	34.78	7	120	2	115	6.0e-20	89.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
651662189	593	42.44	7	573	10	570	0.0e+00	618	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
651662190	250	37.26	5	249	1	251	2.0e-34	139	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651662191	203	33.97	3	203	4	195	4.0e-26	111	COG1335	Nicotinamidase-related amidase	205
651662194	276	36.99	36	276	13	255	1.0e-48	186	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
651662195	373	30.23	13	349	12	346	5.0e-51	195	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
651662197	246	37.33	9	232	10	233	1.0e-45	176	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
651662198	307	20.92	1	305	4	266	3.0e-15	75.9	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
651662199	264	37.01	1	264	1	280	4.0e-55	208	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
651662200	801	38.62	14	793	6	731	0.0e+00	590	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
651662201	165	56.95	1	151	1	150	2.0e-55	208	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
651662202	146	33.33	25	145	12	135	4.0e-08	51.1	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
651662203	430	42.51	225	429	30	225	7.0e-55	208	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
651662204	697	23.55	28	485	1	440	1.0e-25	111	COG0658	Predicted membrane metal-binding protein	453
651662207	219	35.19	1	106	1	104	6.0e-12	64.3	COG5462	Predicted secreted (periplasmic) protein	138
651662208	313	47.48	1	313	1	314	1.0e-101	363	COG0275	16S rRNA C1402 N4-methylase RsmH	314
651662211	580	34.12	265	560	25	309	5.0e-43	169	COG0616	Periplasmic serine protease, ClpP class	317
651662212	191	26.44	8	178	6	171	8.0e-20	90.4	COG3040	Bacterial lipocalin	174
651662213	960	61.39	468	928	29	496	0.0e+00	678	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
651662214	124	50.4	1	123	6	130	2.0e-38	151	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
651662217	372	36.64	76	361	7	285	8.0e-61	227	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
651662218	486	46.74	12	486	4	465	0.0e+00	485	COG2870	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase	467
651662219	290	34.1	7	267	22	269	2.0e-68	252	COG2326	Polyphosphate kinase 2, PPK2 family	270
651662220	240	59.07	1	235	1	237	6.0e-85	307	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
651662221	261	53.36	1	252	1	250	2.0e-88	319	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
651662222	309	38.33	12	305	11	308	4.0e-42	165	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
651662223	300	42.33	1	299	3	297	2.0e-47	183	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
651662224	290	33.33	2	288	76	366	9.0e-39	154	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
651662228	827	35.45	144	826	1	650	0.0e+00	505	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
651662229	357	50.87	1	340	2	335	2.0e-117	415	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
651662231	305	22.56	44	301	5	262	6.0e-13	68.5	COG1729	Periplasmic TolA-binding protein (function unknown)	262
651662232	274	27.35	12	247	23	265	1.0e-25	110	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
651662236	249	48.54	13	249	1	238	2.0e-74	272	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
651662237	275	47.31	1	275	1	273	2.0e-84	305	COG0266	Formamidopyrimidine-DNA glycosylase	273
651662238	205	35.1	1	202	1	205	1.0e-41	162	COG0135	Phosphoribosylanthranilate isomerase	208
651662240	562	57.04	1	544	72	620	0.0e+00	544	COG4547	Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib...	620
651662241	342	26.57	135	339	37	241	1.0e-27	117	COG1360	Flagellar motor protein MotB	244
651662245	174	55.17	1	174	1	171	2.0e-53	201	COG0221	Inorganic pyrophosphatase	171
651662252	464	31.01	15	458	11	432	3.0e-54	206	COG1457	Purine-cytosine permease or related protein	442
651662255	75	45.45	1	75	1	75	3.0e-20	90.3	COG0254	Ribosomal protein L31	75
651662256	153	36.69	1	135	8	145	2.0e-28	118	COG0071	Molecular chaperone IbpA, HSP20 family	146
651662257	209	31.61	12	185	6	166	6.0e-30	124	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
651662258	325	50.61	3	325	1	329	5.0e-95	341	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
651662259	241	58.85	4	237	1	243	7.0e-79	287	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
651662260	374	25.62	10	367	4	364	2.0e-35	143	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
651662261	376	27.96	10	376	1	364	5.0e-38	152	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
651662262	746	23.5	10	742	15	764	1.0e-68	254	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
651662263	427	19.86	8	287	4	278	1.0e-11	64.7	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
651662264	272	46.33	16	272	1	256	1.0e-71	263	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
651662265	288	27.74	134	272	2	146	1.0e-05	44.3	COG3942	Surface antigen	173
651662266	116	36.7	14	116	20	128	1.0e-21	95	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
651662267	274	40.55	53	269	8	224	2.0e-57	215	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
651662269	226	41.15	1	225	71	296	4.0e-66	244	COG1159	GTPase Era, involved in 16S rRNA processing	298
651662270	372	32.3	1	372	1	384	2.0e-44	173	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
651662271	403	33.17	1	402	1	388	4.0e-63	235	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
651662272	567	40.07	26	555	12	528	2.0e-108	386	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
651662273	698	38.69	293	586	2	306	1.0e-74	274	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
651662277	617	54.38	1	613	8	575	0.0e+00	759	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
651662278	405	22.73	9	401	1	394	3.0e-11	63.7	COG2814	Predicted arabinose efflux permease, MFS family	394
651662279	236	52.97	3	232	2	237	1.0e-80	292	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
651662280	254	48.59	1	247	2	250	3.0e-77	281	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
651662281	328	35.99	24	328	5	314	7.0e-44	171	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
651662282	289	34.97	9	286	10	294	6.0e-36	144	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
651662283	420	29.13	35	388	3	356	7.0e-53	201	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
651662284	234	28.38	22	234	9	225	4.0e-35	141	COG0220	tRNA G46 methylase TrmB	227
651662285	395	54.41	4	394	2	387	0.0e+00	542	COG0192	S-adenosylmethionine synthetase	388
651662286	247	39.18	4	247	1	266	2.0e-58	218	COG0289	Dihydrodipicolinate reductase	266
651662287	157	22.37	1	139	8	157	2.0e-07	48.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
651662288	534	32.89	1	446	2	396	1.0e-68	254	COG0644	Dehydrogenase (flavoprotein)	396
651662291	607	50.99	1	607	1	597	0.0e+00	731	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
651662292	437	45.95	1	431	1	457	0.0e+00	482	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
651662293	216	35.05	5	210	5	218	5.0e-34	137	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
651662294	155	33.57	2	139	1	139	2.0e-24	105	COG1959	DNA-binding transcriptional regulator, IscR family	150
651662295	483	45.07	40	481	1	412	1.0e-125	444	COG0719	Fe-S cluster assembly scaffold protein SufB	412
651662296	247	61.63	1	244	3	243	8.0e-99	353	COG0396	Fe-S cluster assembly ATPase SufC	251
651662298	755	40.29	18	755	2	750	0.0e+00	559	COG3605	Signal transduction protein containing GAF and PtsI domains	756
651662299	345	34.12	15	336	11	336	6.0e-46	178	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
651662300	429	44.69	25	427	1	447	3.0e-116	412	COG0527	Aspartokinase	447
651662301	249	46.96	17	246	11	239	2.0e-64	239	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
651662302	317	29.53	15	306	3	297	2.0e-28	120	COG0583	DNA-binding transcriptional regulator, LysR family	297
651662303	518	31.95	14	459	1	467	1.0e-62	234	COG3119	Arylsulfatase A or related enzyme	475
651662304	351	40.79	8	337	2	328	1.0e-74	273	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
651662305	426	27.21	24	426	4	366	5.0e-59	222	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
651662306	363	35.87	28	303	8	266	7.0e-59	221	COG1018	Ferredoxin-NADP reductase	266
651662309	272	50.19	5	260	5	259	7.0e-74	270	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
651662310	140	55.97	1	134	4	137	1.0e-40	158	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
651662312	355	44.74	27	328	25	323	6.0e-88	317	COG0158	Fructose-1,6-bisphosphatase	326
651662313	291	55.17	1	290	1	289	3.0e-119	421	COG3954	Phosphoribulokinase	289
651662314	359	40.61	1	329	1	286	4.0e-92	331	COG0191	Fructose/tagatose bisphosphate aldolase	286
651662315	493	47.6	22	476	1	429	0.0e+00	522	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
651662316	142	39.02	1	123	6	121	2.0e-32	131	COG4451	Ribulose bisphosphate carboxylase small subunit	127
651662318	225	58.33	5	219	2	215	4.0e-80	290	COG0036	Pentose-5-phosphate-3-epimerase	220
651662319	427	28.47	1	426	6	421	7.0e-59	221	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
651662320	195	59.47	6	195	25	214	1.0e-72	265	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
651662321	278	65.49	14	268	3	257	3.0e-111	394	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
651662323	254	36.61	1	252	7	256	9.0e-35	140	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
651662324	245	50.62	2	241	5	243	2.0e-74	272	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
651662325	336	23.51	9	335	7	332	5.0e-24	105	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
651662326	111	34.31	5	101	2	103	1.0e-10	58.1	COG5447	Uncharacterized protein	115
651662327	274	33.33	1	258	3	257	2.0e-33	136	COG2116	Formate/nitrite transporter FocA, FNT family	265
651662329	275	39.52	19	266	18	264	4.0e-57	215	COG1526	Formate dehydrogenase assembly factor FdhD	266
651662330	946	46.02	15	941	1	965	0.0e+00	1239	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
651662331	516	54.78	92	508	1	418	0.0e+00	571	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
651662332	157	41.94	1	155	2	155	5.0e-41	160	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
651662333	299	30.85	1	293	2	292	3.0e-30	125	COG0583	DNA-binding transcriptional regulator, LysR family	297
651662334	357	37.11	3	352	2	335	2.0e-66	246	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
651662335	437	43.26	10	429	2	420	4.0e-100	358	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
651662336	289	56.99	1	284	1	286	3.0e-108	385	COG0777	Acetyl-CoA carboxylase beta subunit	294
651662338	246	45.27	4	238	5	240	1.0e-63	236	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
651662339	421	22.07	61	415	37	383	9.0e-12	65.2	COG2814	Predicted arabinose efflux permease, MFS family	394
651662340	129	29.17	3	122	13	119	7.0e-09	53	COG2149	Uncharacterized membrane protein YidH, DUF202 family	120
651662341	299	39.44	10	288	1	281	5.0e-62	231	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
651662342	172	28.12	43	138	14	109	1.0e-08	52.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
651662345	424	62.77	7	424	8	422	0.0e+00	485	COG2379	Glycerate-2-kinase	422
651662347	76	42.31	1	51	1	52	3.0e-07	46.8	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
651662348	306	23.79	33	271	42	278	1.0e-29	123	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
651662349	271	35.88	5	258	4	254	3.0e-57	215	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
651662350	276	29.69	12	240	17	242	1.0e-16	80.9	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
651662352	171	38.01	5	171	1	169	4.0e-28	117	COG2241	Precorrin-6B methylase 1	210
651662353	248	43.55	1	240	3	248	2.0e-55	208	COG2099	Precorrin-6x reductase	257
651662354	265	47.77	1	246	1	246	3.0e-76	278	COG1010	Precorrin-3B methylase	249
651662355	245	41.91	3	241	1	234	1.0e-56	213	COG2243	Precorrin-2 methylase	234
651662356	209	50	3	205	2	203	6.0e-51	193	COG2082	Precorrin isomerase	210
651662357	382	26.5	1	364	27	460	4.0e-31	129	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
651662359	344	35.19	7	337	1	314	4.0e-69	255	COG0523	GTPase, G3E family	323
651662360	120	43.09	4	120	19	141	2.0e-22	97.7	COG5469	Predicted metal-binding protein	143
651662361	205	56.28	7	205	2	198	1.0e-69	255	COG2109	ATP:corrinoid adenosyltransferase	198
651662362	497	52.57	17	497	1	485	0.0e+00	565	COG1492	Cobyric acid synthase	486
651662363	529	28.77	1	320	5	349	5.0e-43	169	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
651662364	311	47	1	311	5	315	3.0e-68	252	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
651662368	1144	45.15	4	1140	12	1139	0.0e+00	1217	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
651662369	162	23.12	6	143	18	175	5.0e-18	83.8	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
651662370	117	31.03	7	116	9	123	2.0e-16	77.7	COG0073	tRNA-binding EMAP/Myf domain	123
651662371	536	38.59	11	536	11	539	2.0e-130	459	COG0405	Gamma-glutamyltranspeptidase	539
651662374	661	36.07	10	655	7	687	0.0e+00	483	COG0480	Translation elongation factor EF-G, a GTPase	697
651662375	261	39.42	21	260	14	254	7.0e-39	154	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
651662376	240	42.8	1	237	4	250	8.0e-43	167	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651662377	234	30.67	61	207	37	186	1.0e-18	86.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
651662378	156	25.17	5	147	6	136	9.0e-17	79.6	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
651662379	118	36.79	1	103	2	105	1.0e-17	82.3	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
651662380	211	34.51	1	211	2	212	4.0e-40	157	COG0602	Organic radical activating enzyme	212
651662382	405	50	1	401	1	404	0.0e+00	467	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
651662384	87	28	13	86	5	78	8.0e-06	42.2	COG0425	TusA-related sulfurtransferase	78
651662385	197	54.17	49	190	4	147	2.0e-49	189	COG4957	Predicted transcriptional regulator	148
651662386	265	36.29	10	257	6	253	8.0e-65	240	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
651662387	217	49.5	2	203	9	204	1.0e-61	229	COG2945	Alpha/beta superfamily hydrolase	210
651662388	255	63.43	6	180	7	181	7.0e-68	250	COG1045	Serine acetyltransferase	194
651662391	317	37.07	18	305	1	289	3.0e-28	119	COG0583	DNA-binding transcriptional regulator, LysR family	297
651662394	285	29.2	11	274	4	277	2.0e-30	126	COG1792	Cell shape-determining protein MreC	284
651662396	626	32.14	8	600	10	589	2.0e-103	370	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
651662397	386	38.42	26	382	13	378	4.0e-76	278	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
651662398	409	56	5	153	2	150	4.0e-51	195	COG1017	Hemoglobin-like flavoprotein	150
651662400	548	37.82	18	547	3	522	4.0e-112	398	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
651662404	374	24.28	13	357	15	331	1.0e-10	61.1	COG3299	Uncharacterized phage protein gp47/JayE	353
651662409	254	38.43	8	252	1	250	7.0e-35	140	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651662410	355	43.36	1	350	3	359	3.0e-86	312	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
651662411	115	30.97	1	113	3	103	6.0e-10	56.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
651662412	439	56.05	35	438	1	390	0.0e+00	496	COG0372	Citrate synthase	390
651662414	420	35.22	24	415	45	440	4.0e-71	262	COG1793	ATP-dependent DNA ligase	444
651662415	381	52.86	9	356	1	350	3.0e-122	431	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
651662416	164	63.35	1	161	1	159	6.0e-57	213	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
651662417	67	43.75	4	67	5	67	6.0e-06	42.7	COG5481	Uncharacterized protein	67
651662419	195	58.97	2	193	1	193	4.0e-62	230	COG3820	Uncharacterized protein	230
651662420	328	47.88	1	328	2	322	9.0e-105	373	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
651662421	370	45.61	194	356	1	171	4.0e-32	132	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
651662423	205	38.01	9	174	8	178	3.0e-22	98.4	COG3038	Cytochrome b561	181
651662424	458	52.75	7	457	2	455	0.0e+00	474	COG3572	Gamma-glutamylcysteine synthetase	456
651662426	772	37.01	14	772	8	766	0.0e+00	584	COG4775	Outer membrane protein assembly factor BamA	766
651662427	280	19.59	94	237	24	169	2.0e-08	53	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
651662432	439	46.85	10	263	3	248	6.0e-84	304	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
651662433	577	40.04	55	574	2	521	2.0e-125	443	COG4986	ABC-type anion transport system, duplicated permease component	523
651662434	374	38.13	1	374	1	364	6.0e-78	284	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
651662435	519	53.95	1	497	1	501	0.0e+00	556	COG0427	Acyl-CoA hydrolase	501
651662437	239	26.58	2	233	7	243	5.0e-36	144	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
651662439	344	39.56	30	343	7	321	8.0e-70	257	COG0142	Geranylgeranyl pyrophosphate synthase	322
651662440	283	20.24	39	258	37	286	1.0e-13	70.3	COG0657	Acetyl esterase/lipase	312
651662441	451	33.93	27	451	1	438	2.0e-58	220	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
651662442	671	52.01	49	640	2	587	0.0e+00	619	COG0465	ATP-dependent Zn proteases	596
651662443	1570	41.96	33	1568	34	1588	0.0e+00	1262	COG2902	NAD-specific glutamate dehydrogenase	1592
651662444	544	35.66	1	533	2	527	3.0e-108	386	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
651662446	258	35.91	3	251	1	248	3.0e-29	122	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651662447	379	40.27	81	375	10	299	3.0e-56	212	COG2421	Acetamidase/formamidase	305
651662448	260	38.67	10	255	1	251	3.0e-33	135	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651662449	262	20.7	25	248	17	212	6.0e-13	68	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
651662450	432	35.54	22	429	8	377	4.0e-80	292	COG1454	Alcohol dehydrogenase, class IV	377
651662451	320	48.44	31	318	6	294	7.0e-72	264	COG2103	N-acetylmuramic acid 6-phosphate (MurNAc-6-P) etherase	298
651662455	292	40.68	5	292	13	304	7.0e-65	240	COG1488	Nicotinic acid phosphoribosyltransferase	405
651662456	957	65.82	4	944	3	935	0.0e+00	1513	COG0178	Excinuclease UvrABC ATPase subunit	935
651662460	504	48.19	28	494	7	459	0.0e+00	469	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
651662461	295	63.49	1	188	3	191	3.0e-81	295	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
651662463	557	63.06	3	557	1	554	0.0e+00	811	COG2759	Formyltetrahydrofolate synthetase	554
651662464	696	48.55	6	694	1	680	0.0e+00	805	COG1770	Protease II	682
651662466	283	56.54	1	282	6	287	2.0e-113	401	COG0788	Formyltetrahydrofolate hydrolase	287
651662467	204	38.5	1	198	6	203	4.0e-34	137	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
651662468	233	25.25	9	194	7	200	2.0e-08	52.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651662470	392	41.76	13	375	1	361	5.0e-89	321	COG0349	Ribonuclease D	361
651662471	595	53.58	4	587	1	583	0.0e+00	825	COG0173	Aspartyl-tRNA synthetase	585
651662472	329	30.93	5	329	1	326	2.0e-49	189	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
651662473	392	26.57	40	381	34	383	3.0e-08	53.3	COG2814	Predicted arabinose efflux permease, MFS family	394
651662474	550	37.18	9	548	2	529	2.0e-126	446	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
651662475	156	36.3	10	155	2	141	7.0e-29	119	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
651662480	261	42.21	1	259	1	251	1.0e-42	166	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651662481	199	44.12	14	183	9	176	4.0e-46	177	COG0279	Phosphoheptose isomerase	176
651662482	322	32.93	1	317	1	311	1.0e-47	184	COG0451	Nucleoside-diphosphate-sugar epimerase	314
651662483	341	29.78	2	335	81	432	3.0e-45	175	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
651662484	524	50.48	14	425	1	409	4.0e-118	418	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
651662485	273	31.39	1	271	18	280	6.0e-20	91.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
651662487	275	43.4	5	265	1	258	1.0e-63	236	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
651662488	188	37.69	1	130	2	131	4.0e-31	127	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
651662494	309	30.74	6	297	5	295	3.0e-47	182	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
651662497	342	26.95	18	324	15	302	4.0e-26	112	COG0524	Sugar or nucleoside kinase, ribokinase family	311
651662498	255	63.9	9	249	1	240	9.0e-110	389	COG1126	ABC-type polar amino acid transport system, ATPase component	240
651662499	250	45.62	28	243	5	215	5.0e-41	161	COG0765	ABC-type amino acid transport system, permease component	222
651662500	279	31.44	17	272	4	265	9.0e-30	124	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
651662501	225	51.87	7	193	22	206	1.0e-60	226	COG2360	Leu/Phe-tRNA-protein transferase	221
651662502	481	37.57	144	464	63	408	3.0e-47	183	COG0840	Methyl-accepting chemotaxis protein	408
651662504	210	52.38	1	210	1	210	6.0e-66	243	COG0159	Tryptophan synthase alpha chain	265
651662505	404	71.9	11	404	1	394	0.0e+00	708	COG0133	Tryptophan synthase beta chain	396
651662506	186	36.24	22	168	1	146	3.0e-24	105	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
651662507	222	28.8	14	204	14	195	2.0e-24	105	COG0400	Predicted esterase	207
651662509	481	58.59	28	481	6	458	0.0e+00	596	COG0165	Argininosuccinate lyase	459
651662510	200	27.05	48	168	8	127	4.0e-11	61.5	COG0526	Thiol-disulfide isomerase or thioredoxin	127
651662511	409	58.52	5	407	3	403	0.0e+00	584	COG0137	Argininosuccinate synthase	403
651662514	153	35.21	6	147	1	123	3.0e-15	74.6	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
651662515	425	66.35	1	425	1	422	0.0e+00	624	COG0148	Enolase	423
651662516	1319	23.09	1	1319	4	1278	3.0e-72	267	COG2911	Autotransporter translocation and assembly factor TamB	1278
651662517	638	25.73	29	638	15	594	6.0e-61	229	COG0729	Outer membrane translocation and assembly module TamA	594
651662518	324	38.46	7	301	5	288	2.0e-65	242	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
651662519	444	52.87	16	444	1	435	0.0e+00	557	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
651662520	270	28.24	23	264	51	300	2.0e-18	86.3	COG4322	Uncharacterized protein	304
651662521	367	47.73	8	351	3	336	7.0e-110	390	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
651662522	162	45.57	4	161	3	159	2.0e-36	145	COG5328	Uncharacterized protein, UPF0262 family	160
651662523	158	40.59	38	138	14	114	3.0e-15	74.9	COG5349	Uncharacterized conserved protein, DUF983 family	126
651662526	728	65.66	22	685	1	662	0.0e+00	1075	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
651662527	157	22.46	18	148	18	155	1.0e-07	49.3	COG5490	Uncharacterized protein	158
651662529	182	40	13	182	37	204	1.0e-41	162	COG2941	Demethoxyubiquinone hydroxylase, CLK1/Coq7/Cat5 family	204
651662530	158	22.15	5	155	13	168	2.0e-10	58.9	COG1495	Disulfide bond formation protein DsbB	170
651662531	157	50.97	1	155	2	156	1.0e-53	202	COG1225	Peroxiredoxin	157
651662534	149	37.27	34	142	15	124	2.0e-12	65.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
651662536	330	67.07	1	327	13	340	2.0e-122	431	COG1077	Actin-like ATPase involved in cell morphogenesis	342
651662537	140	52.99	2	135	1	134	4.0e-50	190	COG0105	Nucleoside diphosphate kinase	135
651662539	309	26.79	28	305	17	287	1.0e-22	100	COG0382	4-hydroxybenzoate polyprenyltransferase	289
651662541	300	20.95	84	288	19	221	1.0e-06	47.2	COG5012	Methanogenic corrinoid protein MtbC1	227
651662545	631	40.53	46	609	1	524	0.0e+00	529	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
651662547	220	36.95	11	210	1	203	6.0e-37	147	COG2518	Protein-L-isoaspartate O-methyltransferase	209
651662548	522	25.39	20	467	15	457	7.0e-41	162	COG1538	Outer membrane protein TolC	457
651662550	102	44.79	2	97	12	107	2.0e-24	104	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
651662551	151	42.76	2	147	4	155	1.0e-34	138	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
651662554	328	53.85	120	300	1	181	4.0e-43	168	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
651662557	386	47.56	5	383	6	387	2.0e-83	302	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
651662562	830	40.61	2	770	4	764	0.0e+00	702	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
651662563	323	62.76	73	311	1	239	2.0e-97	349	COG1186	Protein chain release factor B	239
651662565	649	32.54	103	639	1	515	1.0e-67	251	COG1657	Squalene cyclase	517
651662566	434	19.31	85	427	65	392	1.0e-09	58.3	COG2814	Predicted arabinose efflux permease, MFS family	394
651662568	137	36.04	5	114	6	116	1.0e-19	88.8	COG0355	FoF1-type ATP synthase, epsilon subunit	135
651662569	476	75.79	6	475	3	468	0.0e+00	817	COG0055	FoF1-type ATP synthase, beta subunit	468
651662570	296	44.86	5	296	1	286	9.0e-83	300	COG0224	FoF1-type ATP synthase, gamma subunit	287
651662571	510	69.02	1	510	1	501	0.0e+00	819	COG0056	FoF1-type ATP synthase, alpha subunit	504
651662572	197	33.71	17	194	2	178	3.0e-34	138	COG0712	FoF1-type ATP synthase, delta subunit	178
651662576	240	47.86	6	237	3	228	2.0e-53	202	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
651662577	235	40.21	29	214	28	213	9.0e-29	120	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
651662578	250	29.61	1	223	1	228	3.0e-27	115	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
651662582	376	33.97	14	367	1	350	5.0e-53	201	COG3405	Endo-1,4-beta-D-glucanase Y	360
651662583	758	24.79	91	563	1	431	4.0e-49	190	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
651662584	927	35.49	77	384	57	368	6.0e-51	196	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
651662586	242	34.16	20	219	7	200	3.0e-35	141	COG0461	Orotate phosphoribosyltransferase	201
651662587	409	31.28	1	400	14	407	2.0e-121	429	COG0538	Isocitrate dehydrogenase	407
651662588	337	26.35	14	330	2	332	3.0e-37	149	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
651662589	519	35.28	23	518	1	453	1.0e-60	227	COG1538	Outer membrane protein TolC	457
651662595	510	44.67	23	505	1	472	0.0e+00	487	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
651662596	129	66.07	8	119	5	116	3.0e-43	167	COG3564	Uncharacterized conserved protein, DUF779 family	116
651662597	570	27.38	9	570	109	754	4.0e-79	289	COG4993	Glucose dehydrogenase	773
651662599	146	28.46	2	119	7	127	9.0e-03	33	COG2010	Cytochrome c, mono- and diheme variants	150
651662608	526	56.61	22	521	12	525	0.0e+00	745	COG4108	Peptide chain release factor RF-3	528
651662609	364	27.86	6	316	3	317	2.0e-48	186	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
651662610	157	37.4	32	154	2	123	2.0e-25	108	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
651662624	423	45.64	20	414	1	396	8.0e-109	387	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
651662625	224	44.64	1	221	22	250	3.0e-27	115	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651662627	309	41.48	44	306	2	267	7.0e-69	253	COG1348	Nitrogenase subunit NifH, an ATPase	278
651662629	523	24.27	12	405	36	430	9.0e-27	115	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
651662632	158	67.72	1	158	1	157	6.0e-56	210	COG0315	Molybdenum cofactor biosynthesis enzyme	157
651662633	270	54.65	10	267	1	254	3.0e-83	301	COG0134	Indole-3-glycerol phosphate synthase	254
651662635	295	29.93	14	293	23	299	3.0e-50	192	COG1560	Lauroyl/myristoyl acyltransferase	308
651662636	469	25.45	8	445	7	446	8.0e-29	122	COG0531	Amino acid transporter	466
651662637	354	44.73	5	354	4	345	2.0e-117	415	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
651662639	256	36.33	6	254	5	259	2.0e-43	169	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
651662640	474	46.34	206	327	13	134	1.0e-26	114	COG3474	Cytochrome c2	135
651662641	247	47.56	8	247	4	244	1.0e-73	269	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
651662642	287	40.86	1	276	1	278	6.0e-76	277	COG0077	Prephenate dehydratase	279
651662645	199	52.43	13	195	1	184	2.0e-53	202	COG0164	Ribonuclease HII	199
651662646	164	46.53	22	163	5	148	8.0e-33	133	COG3260	Ni,Fe-hydrogenase III small subunit	148
651662649	531	26.59	18	529	18	433	2.0e-111	396	COG2224	Isocitrate lyase	433
651662650	227	26.4	1	176	3	180	1.0e-05	43.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
651662651	499	31.7	11	435	2	423	2.0e-79	290	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
651662652	286	32.55	5	259	4	248	1.0e-37	150	COG0300	Short-chain dehydrogenase	265
651662653	305	41.26	43	301	46	312	6.0e-38	151	COG0657	Acetyl esterase/lipase	312
651662654	437	24.25	40	437	70	468	5.0e-44	172	COG5338	Uncharacterized protein	468
651662655	181	48.8	2	159	33	197	3.0e-36	144	COG1573	Uracil-DNA glycosylase	202
651662656	582	29.73	281	563	2	296	9.0e-22	98.7	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
651662657	558	33.74	15	248	26	268	8.0e-11	62.3	COG0457	Tetratricopeptide (TPR) repeat	291
651662658	351	33.82	1	332	3	335	1.0e-48	187	COG0673	Predicted dehydrogenase	342
651662659	328	36.7	1	323	3	319	1.0e-42	167	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651662660	365	45.92	23	352	1	314	5.0e-59	221	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651662661	504	46.72	1	500	4	500	0.0e+00	545	COG1129	ABC-type sugar transport system, ATPase component	500
651662662	216	36.63	41	212	45	204	8.0e-24	103	COG5618	Predicted periplasmic lipoprotein	206
651662663	251	35.12	4	243	1	241	1.0e-38	153	COG2186	DNA-binding transcriptional regulator, FadR family	241
651662664	421	37.15	1	418	11	421	2.0e-98	353	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
651662665	334	31.5	1	325	17	322	5.0e-35	142	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
651662666	157	52.87	1	156	1	156	2.0e-44	171	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
651662667	784	36.94	6	782	4	730	2.0e-129	456	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
651662668	470	22.25	15	376	15	329	2.0e-15	77.7	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
651662669	246	36.96	12	235	5	211	7.0e-53	200	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
651662670	255	55.73	4	252	2	252	5.0e-70	257	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
651662671	177	35.09	13	177	4	171	8.0e-29	120	COG3807	SH3-like domain	171
651662673	219	26.77	96	219	12	138	3.0e-09	55.3	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
651662675	179	54.02	1	174	26	198	4.0e-58	217	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
651662677	313	51.78	10	311	2	310	5.0e-112	397	COG0078	Ornithine carbamoyltransferase	310
651662678	393	50.13	1	382	18	398	0.0e+00	462	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
651662679	498	29.25	9	458	1	459	7.0e-67	248	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
651662680	176	25	20	148	40	160	4.0e-08	51.1	COG4731	Uncharacterized conserved protein, DUF2147 family	162
651662681	331	25.25	35	318	30	324	2.0e-23	103	COG3528	Uncharacterized protein	330
651662682	97	58.33	2	97	12	107	4.0e-33	132	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
651662683	775	48.21	1	753	1	786	0.0e+00	870	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
651662685	330	28.12	19	320	75	387	1.0e-43	170	COG0247	Fe-S oxidoreductase	388
651662687	338	29.45	1	338	1	281	1.0e-36	147	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
651662688	349	30.06	6	340	2	335	2.0e-44	173	COG0673	Predicted dehydrogenase	342
651662689	338	29.72	7	327	12	315	6.0e-23	101	COG0530	Ca2+/Na+ antiporter	320
651662692	302	41.78	1	302	14	315	4.0e-42	165	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651662693	433	51.99	31	429	94	493	0.0e+00	477	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
651662695	337	26.54	16	337	5	324	6.0e-40	158	COG1868	Flagellar motor switch protein FliM	332
651662696	511	47.07	1	510	3	548	0.0e+00	623	COG0143	Methionyl-tRNA synthetase	558
651662698	210	43.96	4	208	2	208	7.0e-53	200	COG0125	Thymidylate kinase	208
651662701	320	41.18	1	319	2	317	1.0e-68	253	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
651662702	127	35.96	13	124	1	110	4.0e-23	100	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
651662703	159	46.07	48	136	1	89	3.0e-21	94.5	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
651662704	254	65.49	1	250	1	255	8.0e-104	369	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
651662705	246	47.92	2	241	1	236	9.0e-75	273	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
651662706	171	28.46	36	157	34	153	3.0e-07	48.7	COG1247	L-amino acid N-acyltransferase YncA	169
651662707	211	47.87	1	211	2	204	8.0e-70	256	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
651662708	196	62.76	1	196	2	195	1.0e-74	272	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
651662709	391	21.15	1	377	50	384	9.0e-07	48.3	COG2814	Predicted arabinose efflux permease, MFS family	394
651662710	302	34.97	9	293	2	286	2.0e-63	236	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
651662711	211	39.23	1	204	3	206	3.0e-42	165	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
651662712	192	26.88	1	90	1	93	6.0e-08	51.1	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
651662714	385	21.04	17	381	20	325	2.0e-14	73.7	COG2814	Predicted arabinose efflux permease, MFS family	394
651662716	469	35.35	57	466	20	423	5.0e-72	265	COG0823	Periplasmic component of the Tol biopolymer transport system	425
651662718	473	45.24	7	466	6	459	0.0e+00	487	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
651662719	234	26.29	9	227	4	218	1.0e-21	97.3	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
651662722	549	49.09	1	534	1	523	0.0e+00	514	COG0459	Chaperonin GroEL (HSP60 family)	524
651662723	104	69.47	1	95	1	95	3.0e-34	136	COG0234	Co-chaperonin GroES (HSP10)	96
651662724	85	59.21	3	78	7	82	2.0e-24	103	COG5425	Usg protein (tryptophan operon, function unknown)	90
651662726	340	20.41	31	270	39	282	1.0e-35	143	COG5410	Uncharacterized protein	305
651662729	249	26.7	62	249	1	187	2.0e-14	72.8	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
651662731	171	28.48	1	165	1	163	4.0e-26	111	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
651662733	103	51.04	1	95	1	96	9.0e-23	98.4	COG5470	Uncharacterized conserved protein, DUF1330 family	96
651662737	328	57.32	11	324	2	327	2.0e-114	405	COG1494	Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase or related protein	332
651662738	429	48.62	5	322	4	330	5.0e-93	335	COG0460	Homoserine dehydrogenase	333
651662739	403	43.33	9	390	5	390	2.0e-104	372	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
651662742	599	53.23	148	596	7	445	0.0e+00	552	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
651662744	520	26.03	14	434	21	452	7.0e-39	155	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
651662745	95	27.37	1	95	11	101	1.0e-03	35.1	COG3293	Transposase	124
651662747	251	34.52	1	249	6	255	3.0e-48	185	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
651662748	226	49.25	13	213	1	201	6.0e-59	220	COG2039	Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)	207
651662749	286	28.47	18	286	2	282	3.0e-20	92.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
651662750	644	45.86	67	621	1	525	0.0e+00	669	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
651662751	234	42.86	1	230	94	324	4.0e-63	234	COG0280	Phosphotransacetylase	327
651662752	412	47.65	11	410	21	422	1.0e-113	403	COG0513	Superfamily II DNA and RNA helicase	513
651662754	421	55.56	1	421	1	423	0.0e+00	522	COG0151	Phosphoribosylamine-glycine ligase	428
651662758	264	35.05	36	248	18	230	1.0e-32	133	COG1802	DNA-binding transcriptional regulator, GntR family	230
651662759	503	50.87	101	503	2	381	0.0e+00	480	COG2721	Altronate dehydratase	381
651662760	241	53.19	4	237	3	236	1.0e-81	296	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
651662761	599	52.99	345	593	2	249	2.0e-81	297	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
651662762	294	44.3	1	293	2	297	3.0e-50	192	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
651662763	373	33.33	21	359	4	349	8.0e-47	181	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
651662764	223	35.51	1	214	2	208	4.0e-39	155	COG0132	Dethiobiotin synthetase	223
651662765	381	45.83	4	375	3	386	3.0e-103	368	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
651662766	325	55.88	19	322	15	318	6.0e-113	400	COG0502	Biotin synthase or related enzyme	335
651662767	418	43.12	1	417	2	443	9.0e-128	450	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
651662770	307	38.31	30	290	4	253	9.0e-59	220	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
651662771	575	52.45	18	563	1	541	0.0e+00	577	COG0539	Ribosomal protein S1	541
651662773	222	29.22	1	217	2	211	7.0e-17	80.8	COG4649	Uncharacterized protein	221
651662775	451	48.31	8	450	3	444	0.0e+00	532	COG1160	Predicted GTPases	444
651662778	156	38.93	6	154	3	148	1.0e-27	115	COG1610	Uncharacterized conserved protein YqeY	148
651662782	48	46.51	2	44	13	55	3.0e-07	46.8	COG1773	Rubredoxin	55
651662783	113	43.75	1	112	1	112	4.0e-23	99	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
651662784	297	42.03	64	266	1	200	8.0e-58	217	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
651662787	260	35	3	253	1	249	9.0e-28	117	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651662788	325	36.09	60	320	4	250	4.0e-39	155	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
651662789	167	22.73	33	163	7	130	8.0e-08	50.4	COG1765	Uncharacterized OsmC-related protein	137
651662790	436	29.62	8	414	20	432	3.0e-45	176	COG0038	H+/Cl- antiporter ClcA	443
651662795	298	32.33	3	297	2	296	2.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
651662796	191	21.18	1	170	8	176	2.0e-05	42.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
651662797	153	76.35	6	153	7	154	8.0e-65	239	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
651662798	107	32.5	9	88	4	83	5.0e-11	59.6	COG1359	Quinol monooxygenase YgiN	100
651662799	142	41.04	1	134	55	187	1.0e-26	112	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
651662800	200	40.98	1	200	6	208	7.0e-57	213	COG0253	Diaminopimelate epimerase	272
651662801	489	21.11	38	465	36	448	3.0e-14	74	COG0531	Amino acid transporter	466
651662802	218	54.19	1	203	1	203	5.0e-74	270	COG0177	Endonuclease III	211
651662803	166	32.24	6	156	13	164	2.0e-22	98.8	COG5488	Uncharacterized membrane protein	164
651662810	891	51.29	2	891	1	876	0.0e+00	1130	COG0525	Valyl-tRNA synthetase	877
651662811	276	31.25	23	256	1	239	4.0e-22	98.6	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
651662815	442	37.93	5	433	1	429	2.0e-100	359	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
651662817	194	21.29	4	190	1	201	1.0e-17	83.5	COG0778	Nitroreductase	207
651662818	185	49.41	102	184	1	85	2.0e-23	102	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
651662821	200	32.41	1	185	7	222	1.0e-14	73.4	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
651662822	691	24.27	139	663	60	568	1.0e-55	211	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
651662823	84	53.52	5	75	7	77	7.0e-25	105	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
651662824	120	36.27	8	108	6	105	5.0e-11	59.9	COG0594	RNase P protein component	117
651662826	326	23.33	28	325	11	281	5.0e-25	108	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
651662827	465	25.69	145	464	10	331	7.0e-28	118	COG0642	Signal transduction histidine kinase	336
651662828	253	46.77	1	248	1	247	2.0e-66	245	COG1338	Flagellar biosynthetic protein FliP	248
651662829	126	27.78	4	122	6	130	4.0e-11	60.7	COG1815	Flagellar basal body rod protein FlgB	133
651662830	134	44.85	1	133	1	135	3.0e-36	144	COG1558	Flagellar basal body rod protein FlgC	137
651662831	100	27.08	6	100	10	105	9.0e-10	55.3	COG1677	Flagellar hook-basal body complex protein FliE	105
651662832	110	45.12	23	104	1	82	1.0e-12	64.8	COG1987	Flagellar biosynthesis protein FliQ	89
651662833	259	28.46	6	258	8	252	2.0e-21	96.4	COG1684	Flagellar biosynthesis protein FliR	258
651662834	324	33.44	2	316	34	350	3.0e-62	232	COG1377	Flagellar biosynthesis protein FlhB	363
651662835	194	39.06	2	190	22	207	7.0e-30	123	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
651662836	311	38.71	5	310	7	304	3.0e-56	212	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
651662837	120	63.79	4	119	3	118	1.0e-39	155	COG3536	Uncharacterized conserved protein, DUF971 family	120
651662838	61	60	7	61	1	55	4.0e-15	72.9	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
651662840	150	49.65	5	145	1	143	2.0e-39	154	COG0698	Ribose 5-phosphate isomerase RpiB	151
651662841	432	67.06	13	431	2	412	0.0e+00	656	COG0112	Glycine/serine hydroxymethyltransferase	413
651662842	151	59.72	1	144	1	144	3.0e-50	190	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
651662843	273	61.97	2	143	5	146	2.0e-49	189	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
651662846	273	32.28	1	272	1	274	3.0e-26	112	COG0524	Sugar or nucleoside kinase, ribokinase family	311
651662849	258	35.08	12	248	3	250	8.0e-53	200	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
651662852	281	60.07	4	279	1	277	2.0e-95	342	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
651662855	486	40.71	7	485	1	473	2.0e-72	266	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
651662856	505	49.3	1	497	4	493	0.0e+00	462	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
651662857	618	44.46	5	614	1	606	9.0e-116	411	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
651662858	102	46.46	4	102	2	100	1.0e-18	84.4	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
651662859	166	35	1	160	4	163	2.0e-11	62.6	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
651662860	170	43.79	5	155	16	163	1.0e-39	156	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
651662861	323	56.35	7	322	11	332	2.0e-92	332	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
651662864	376	27.56	21	326	5	313	1.0e-33	137	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651662865	304	35.89	7	290	2	277	1.0e-57	217	COG3386	Sugar lactone lactonase YvrE	307
651662866	206	32.86	1	206	3	211	1.0e-41	163	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
651662867	296	43.97	2	275	8	287	8.0e-54	204	COG3734	2-keto-3-deoxy-galactonokinase	306
651662868	257	29.37	11	256	2	250	2.0e-40	159	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651662870	324	37.7	12	320	3	314	4.0e-41	162	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651662871	230	27.88	12	230	5	225	2.0e-30	125	COG0412	Dienelactone hydrolase	236
651662872	376	35.92	16	373	27	391	4.0e-74	272	COG0019	Diaminopimelate decarboxylase	394
651662873	239	44.21	5	235	1	228	2.0e-55	209	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
651662874	454	30.82	173	453	44	328	2.0e-35	144	COG0642	Signal transduction histidine kinase	336
651662875	433	21.75	80	431	67	407	2.0e-07	51	COG2223	Nitrate/nitrite transporter NarK	417
651662878	227	33.48	1	223	25	249	9.0e-28	117	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651662880	292	54.58	1	292	4	298	9.0e-93	333	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
651662881	159	49.31	16	159	9	151	5.0e-44	170	COG0691	tmRNA-binding protein	153
651662882	229	37.95	43	228	56	250	3.0e-44	171	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
651662883	161	51.83	1	159	2	165	1.0e-56	212	COG0678	Peroxiredoxin	165
651662886	165	46.58	17	160	3	146	3.0e-43	167	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
651662887	268	53.94	2	255	6	259	5.0e-93	334	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
651662888	409	20.16	1	379	8	391	2.0e-12	67.2	COG2814	Predicted arabinose efflux permease, MFS family	394
651662889	333	26.14	1	317	122	446	7.0e-42	164	COG0527	Aspartokinase	447
651662890	217	28.42	15	201	1	184	2.0e-34	139	COG0431	NAD(P)H-dependent FMN reductase	184
651662894	234	39.92	4	234	12	251	5.0e-52	197	COG0631	Serine/threonine protein phosphatase PrpC	262
651662895	184	23.91	8	184	5	188	2.0e-08	52.7	COG3009	Uncharacterized lipoprotein YmbA	190
651662896	541	25.31	1	539	4	540	1.0e-55	211	COG3008	Paraquat-inducible protein B	553
651662899	327	34.52	25	301	5	271	2.0e-50	193	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
651662900	144	43.36	9	120	9	118	3.0e-19	87.8	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
651662902	180	23.98	7	174	69	239	5.0e-08	50.9	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
651662905	247	41.67	5	219	2	199	5.0e-50	191	COG0437	Fe-S-cluster-containing dehydrogenase component	203
651662906	935	24.2	18	912	42	765	1.0e-89	325	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
651662910	187	43.58	1	176	76	251	3.0e-28	118	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651662912	346	30.7	1	329	2	313	2.0e-41	163	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651662913	360	38.2	39	359	4	313	9.0e-55	207	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651662915	346	47.19	48	313	1	265	2.0e-87	316	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
651662916	95	56.19	1	95	5	109	2.0e-26	110	COG3460	1,2-phenylacetyl-CoA epoxidase, PaaB subunit	117
651662917	258	42.57	13	258	20	265	1.0e-55	209	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
651662918	118	35.58	4	104	9	111	1.0e-15	74.9	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
651662919	199	32.47	1	192	71	249	9.0e-19	86.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651662920	473	29.84	9	473	7	486	6.0e-63	235	COG1070	Sugar (pentulose or hexulose) kinase	502
651662921	631	32.84	213	592	1	408	8.0e-51	195	COG0840	Methyl-accepting chemotaxis protein	408
651662922	186	39.06	120	182	4	67	7.0e-08	50.5	COG1278	Cold shock protein, CspA family	67
651662927	321	24.87	8	319	45	426	1.0e-43	170	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
651662931	329	46.06	1	328	2	316	3.0e-91	328	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
651662932	325	47.1	5	311	23	332	2.0e-100	359	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
651662933	149	61.11	6	149	3	146	6.0e-58	216	COG0757	3-dehydroquinate dehydratase	146
651662935	430	39.68	1	424	1	421	8.0e-95	341	COG1253	Hemolysin or related protein, contains CBS domains	429
651662936	854	33.46	11	267	40	305	3.0e-52	201	COG5309	Exo-beta-1,3-glucanase,  GH17 family	305
651662937	370	51.62	3	368	2	348	1.0e-115	409	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
651662938	207	56.28	2	200	1	191	1.0e-72	265	COG0066	3-isopropylmalate dehydratase small subunit	191
651662939	466	57.45	1	466	1	423	0.0e+00	611	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
651662940	550	28.49	44	540	17	543	3.0e-75	276	COG0747	ABC-type transport system, periplasmic component	556
651662941	321	37.97	5	318	1	316	4.0e-66	245	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
651662942	283	41.04	17	283	16	283	9.0e-60	223	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
651662944	622	35.21	46	613	1	564	7.0e-108	385	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
651662945	349	24.93	6	341	2	381	2.0e-27	116	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651662948	160	38.62	14	152	18	160	8.0e-15	73.4	COG1267	Phosphatidylglycerophosphatase A	160
651662950	554	37.05	285	531	5	254	8.0e-52	198	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
651662951	170	28.16	1	170	5	178	2.0e-11	62.2	COG2059	Chromate transport protein ChrA	195
651662955	379	29.41	8	379	4	379	3.0e-30	126	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651662956	252	25.95	7	230	14	272	4.0e-09	55.4	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
651662957	154	44.26	35	153	5	125	8.0e-29	119	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
651662958	287	47.02	1	285	1	280	2.0e-73	269	COG0421	Spermidine synthase	282
651662959	318	55.1	1	314	1	314	1.0e-115	409	COG0825	Acetyl-CoA carboxylase alpha subunit	317
651662960	383	46.04	2	383	1	391	5.0e-96	344	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
651662962	301	65.29	5	295	2	291	0.0e+00	498	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
651662963	666	42.69	1	666	3	691	0.0e+00	660	COG0751	Glycyl-tRNA synthetase, beta subunit	691
651662964	889	28.52	5	881	1	739	0.0e+00	636	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
651662967	450	46.38	6	443	1	435	0.0e+00	512	COG0621	tRNA A37 methylthiotransferase MiaB	437
651662968	333	50	11	333	13	342	2.0e-94	339	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
651662969	150	31.78	31	145	21	149	2.0e-20	91.9	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
651662974	607	31.61	165	599	1	443	2.0e-88	320	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
651662976	185	24.85	16	182	8	174	3.0e-11	62.1	COG4961	Flp pilus assembly protein TadG	185
651662978	76	44.16	1	76	1	77	2.0e-19	87.6	COG3254	L-rhamnose mutarotase	105
651662981	329	19.75	1	320	1	289	2.0e-17	83.6	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
651662982	224	48.9	1	222	27	250	4.0e-64	237	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
651662985	470	65.81	1	464	1	464	0.0e+00	662	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
651662986	262	40.24	11	259	12	257	4.0e-36	145	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
651662987	503	46.89	2	503	23	526	0.0e+00	601	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
651662988	307	29.27	9	246	13	251	9.0e-26	111	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
651662990	310	19.48	9	301	3	300	4.0e-15	75.9	COG1216	Glycosyltransferase, GT2 family	305
651662991	331	23.3	1	322	2	323	9.0e-13	68	COG3594	Fucose 4-O-acetylase or related acetyltransferase	343
651662995	349	49.42	1	342	1	329	5.0e-95	341	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
651662996	363	26.3	50	329	29	314	2.0e-23	103	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651662997	524	50.2	16	518	3	500	0.0e+00	550	COG1129	ABC-type sugar transport system, ATPase component	500
651662998	334	37.06	13	324	2	312	6.0e-47	181	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651662999	328	37.1	20	327	3	310	9.0e-40	157	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651663000	254	57.49	5	251	2	237	5.0e-99	354	COG1126	ABC-type polar amino acid transport system, ATPase component	240
651663001	250	43.1	1	232	1	220	7.0e-55	207	COG0765	ABC-type amino acid transport system, permease component	222
651663002	274	31.77	7	273	1	271	1.0e-28	120	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
651663003	391	24.25	34	391	9	367	1.0e-24	107	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
651663005	504	26.84	7	499	1	448	2.0e-52	200	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
651663006	324	41.1	14	305	2	293	4.0e-65	241	COG1230	Co/Zn/Cd efflux system component	296
651663008	131	36.04	4	113	3	113	4.0e-18	83.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
651663010	92	46.15	1	91	1	89	1.0e-16	78.3	COG1937	DNA-binding transcriptional regulator, FrmR family	89
651663012	473	32	58	473	13	397	5.0e-75	275	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
651663013	395	29.87	1	393	25	408	1.0e-40	160	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
651663014	143	29.37	19	143	4	119	3.0e-15	74.5	COG1539	Dihydroneopterin aldolase	121
651663017	325	45.87	4	325	2	326	8.0e-71	260	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
651663021	106	37.33	1	75	1	75	2.0e-09	53.8	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
651663022	185	35.45	10	185	5	191	5.0e-27	113	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
651663023	381	38.63	24	380	30	392	4.0e-72	265	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
651663025	312	52.73	3	305	30	340	3.0e-94	338	COG0552	Signal recognition particle GTPase	340
651663026	411	39.49	1	408	3	433	7.0e-117	414	COG0621	tRNA A37 methylthiotransferase MiaB	437
651663028	238	30.77	31	234	62	282	2.0e-20	92.4	COG0790	TPR repeat	292
651663030	97	38.14	1	97	1	87	1.0e-16	78.5	COG0271	Stress-induced morphogen (activity unknown)	90
651663036	504	56.63	161	355	1	190	3.0e-50	193	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
651663037	174	35.06	9	161	4	153	2.0e-32	131	COG0779	Ribosome maturation factor RimP	153
651663038	208	22.73	13	200	8	200	3.0e-20	91.9	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
651663039	266	37.45	1	242	2	234	2.0e-46	179	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
651663040	310	40.69	24	308	7	291	1.0e-68	253	COG0685	5,10-methylenetetrahydrofolate reductase	291
651663043	103	61.64	3	75	1	73	4.0e-28	115	COG1923	sRNA-binding regulator protein Hfq	77
651663044	435	44.2	27	427	16	411	2.0e-109	390	COG2262	50S ribosomal subunit-associated GTPase HflX	411
651663045	277	33.46	1	265	1	250	1.0e-42	167	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
651663048	149	41.38	31	145	5	120	2.0e-24	105	COG1321	Mn-dependent transcriptional regulator, DtxR family	154
651663050	312	22.29	6	308	4	350	3.0e-20	92.8	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
651663051	322	39.85	24	287	1	269	1.0e-56	213	COG1348	Nitrogenase subunit NifH, an ATPase	278
651663055	506	26	64	192	36	182	1.0e-03	38.8	COG2976	Putative negative regulator of RcsB-dependent stress response	207
651663056	141	57.04	1	141	15	156	3.0e-46	177	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
651663061	307	28.42	31	302	1	282	2.0e-12	67	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
651663062	509	33.2	16	495	2	472	2.0e-76	280	COG1233	Phytoene dehydrogenase-related protein	487
651663063	353	34.74	1	280	3	286	8.0e-36	144	COG1562	Phytoene/squalene synthetase	288
651663066	316	27.92	16	294	2	261	4.0e-16	79	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
651663067	344	42.69	1	334	34	366	2.0e-89	322	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
651663068	546	22.32	5	546	10	554	2.0e-53	204	COG2831	Hemolysin activation/secretion protein	554
651663071	320	24.59	12	311	1	297	1.0e-26	113	COG0583	DNA-binding transcriptional regulator, LysR family	297
651663075	276	26.18	4	263	1	275	1.0e-22	100	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
651663076	242	39.46	11	232	4	219	1.0e-40	159	COG0765	ABC-type amino acid transport system, permease component	222
651663077	241	55.6	1	241	1	240	3.0e-94	337	COG1126	ABC-type polar amino acid transport system, ATPase component	240
651663078	432	33.25	11	432	8	431	8.0e-79	287	COG0015	Adenylosuccinate lyase	438
651663080	347	25.62	1	321	1	316	6.0e-31	128	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651663083	336	54.04	65	334	1	263	5.0e-83	301	COG0548	Acetylglutamate kinase	265
651663084	209	44.04	12	204	1	192	2.0e-54	205	COG0218	GTP-binding protein EngB required for normal cell division	200
651663085	534	37.73	200	518	3	295	5.0e-62	232	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
651663086	313	41.58	1	300	16	315	2.0e-72	265	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
651663087	212	54.82	10	205	1	195	8.0e-71	259	COG0302	GTP cyclohydrolase I	195
651663088	142	52.1	19	137	7	124	5.0e-39	153	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
651663089	448	29.85	22	426	15	397	6.0e-43	168	COG2223	Nitrate/nitrite transporter NarK	417
651663092	204	48.28	1	202	1	193	1.0e-64	239	COG0307	Riboflavin synthase alpha chain	204
651663093	375	60.4	13	214	3	203	5.0e-77	281	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
651663094	160	37.16	12	156	6	152	7.0e-28	116	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
651663095	165	36	9	158	8	149	4.0e-21	94.2	COG0781	Transcription termination factor NusB	151
651663096	312	41.56	1	312	2	317	4.0e-64	238	COG0611	Thiamine monophosphate kinase	317
651663099	152	52.52	13	149	4	130	2.0e-36	145	COG1970	Large-conductance mechanosensitive channel	130
651663100	353	51.47	6	341	2	337	9.0e-95	340	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
651663101	154	50.78	21	147	22	149	9.0e-47	179	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
651663102	376	54.22	6	372	1	367	0.0e+00	494	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
651663103	275	50.55	3	274	77	344	7.0e-91	327	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
651663105	472	48.47	10	452	6	457	2.0e-120	426	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
651663107	305	50.79	116	304	41	225	3.0e-57	215	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
651663110	426	49.28	5	416	10	424	2.0e-123	435	COG2907	Predicted NAD/FAD-binding protein	447
651663111	254	42.68	4	246	7	252	2.0e-53	202	COG3496	Uncharacterized conserved protein, DUF1365 family	261
651663112	405	47.04	118	404	3	283	2.0e-87	316	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
651663115	396	17.17	1	396	1	370	2.0e-21	96.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651663117	115	63.37	6	105	1	101	1.0e-40	158	COG0278	Glutaredoxin-related protein	105
651663118	77	36.47	1	77	1	85	3.0e-17	80	COG0271	Stress-induced morphogen (activity unknown)	90
651663119	727	50.27	4	720	12	743	0.0e+00	868	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
651663120	231	52	1	224	3	226	9.0e-78	283	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
651663123	264	41.18	1	254	3	256	6.0e-50	191	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
651663126	194	41.08	1	181	12	195	3.0e-37	148	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
651663128	188	50.26	1	188	2	191	6.0e-53	200	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
651663129	72	66.67	1	72	1	72	4.0e-23	99.5	COG0361	Translation initiation factor IF-1	75
651663130	436	55.58	2	429	1	423	0.0e+00	492	COG0141	Histidinol dehydrogenase	425
651663131	231	42.66	18	231	3	216	3.0e-50	191	COG0040	ATP phosphoribosyltransferase	290
651663132	330	24.84	27	326	1	305	4.0e-42	165	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
651663133	392	44.42	2	391	4	396	2.0e-99	356	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
651663134	290	50.53	2	285	1	285	6.0e-83	300	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
651663137	394	51.7	41	390	1	343	2.0e-121	428	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
651663138	235	33.86	1	228	3	251	5.0e-31	128	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651663139	100	52.11	1	71	1	71	2.0e-16	77.6	COG0227	Ribosomal protein L28	77
651663140	167	43.98	2	167	1	166	4.0e-42	163	COG5465	Uncharacterized protein	166
651663144	509	48.12	1	504	1	500	0.0e+00	540	COG1129	ABC-type sugar transport system, ATPase component	500
651663145	336	29.82	11	284	8	282	1.0e-37	150	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651663146	268	42.46	19	268	3	253	3.0e-53	202	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
651663147	388	43.44	2	385	44	427	3.0e-114	405	COG4952	L-rhamnose isomerase	430
651663148	474	43.84	24	429	14	404	3.0e-110	392	COG3347	Rhamnose utilisation protein RhaD, predicted bifunctional aldolase and dehydrogenase	404
651663150	555	36.73	240	538	85	408	2.0e-41	164	COG0840	Methyl-accepting chemotaxis protein	408
651663152	154	58.5	1	147	1	146	7.0e-48	183	COG0756	dUTPase	148
651663153	265	30.68	11	250	9	259	2.0e-34	139	COG0300	Short-chain dehydrogenase	265
651663154	513	52.16	1	510	1	505	0.0e+00	641	COG3046	Uncharacterized protein related to deoxyribodipyrimidine photolyase	505
651663158	275	34.02	1	270	10	298	2.0e-41	163	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
651663159	221	26.64	1	211	1	201	7.0e-23	101	COG0625	Glutathione S-transferase	211
651663160	318	31.68	10	316	12	332	3.0e-61	229	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
651663161	320	29.78	74	250	1	176	7.0e-23	101	COG1633	Rubrerythrin	176
651663162	348	55.49	1	343	55	400	2.0e-100	359	COG0004	Ammonia channel protein AmtB	409
651663165	413	30.33	22	407	4	366	3.0e-54	206	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
651663166	432	23.64	14	418	25	437	4.0e-27	116	COG2271	Sugar phosphate permease	448
651663168	156	47.55	7	149	6	147	1.0e-30	125	COG1522	DNA-binding transcriptional regulator, Lrp family	154
651663169	801	27.33	3	784	72	863	0.0e+00	660	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
651663172	147	46.32	9	144	2	137	7.0e-35	139	COG0848	Biopolymer transport protein ExbD	137
651663173	238	44.04	22	237	1	216	5.0e-45	174	COG0811	Biopolymer transport protein ExbB/TolQ	216
651663174	166	41.22	16	146	5	134	2.0e-27	115	COG0824	Acyl-CoA thioesterase FadM	137
651663177	84	48.72	1	78	1	78	3.0e-09	53.3	COG1314	Preprotein translocase subunit SecG	86
651663180	397	40.47	19	396	11	383	8.0e-94	337	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
651663184	407	19.95	39	404	6	406	3.0e-16	79.9	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
651663185	465	37.86	12	465	21	471	7.0e-101	361	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
651663186	486	45.26	14	485	1	469	4.0e-121	428	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
651663187	516	21.77	39	498	20	464	1.0e-24	108	COG0531	Amino acid transporter	466
651663188	110	34.74	3	96	33	127	9.0e-13	65.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
651663192	99	27.66	1	94	3	96	1.0e-16	77.7	COG1359	Quinol monooxygenase YgiN	100
651663193	158	41.82	4	113	3	112	3.0e-24	104	COG0360	Ribosomal protein S6	112
651663194	92	68.12	21	89	6	74	3.0e-20	89.9	COG0238	Ribosomal protein S18	75
651663195	338	30.19	21	317	13	303	5.0e-21	95.3	COG3301	Formate-dependent nitrite reductase, membrane component NrfD	305
651663196	180	40.76	1	179	8	191	8.0e-39	153	COG0437	Fe-S-cluster-containing dehydrogenase component	203
651663197	731	28.61	1	728	2	763	8.0e-96	345	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
651663198	263	32.07	29	262	8	236	2.0e-33	136	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
651663200	445	47.1	1	444	1	438	0.0e+00	474	COG0015	Adenylosuccinate lyase	438
651663201	212	29.86	18	210	18	223	6.0e-23	101	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
651663203	304	39.07	11	303	5	305	9.0e-58	217	COG0010	Arginase family enzyme	305
651663206	199	59.2	1	199	1	200	3.0e-75	274	COG0414	Panthothenate synthetase	285
651663207	560	35.87	24	534	3	513	2.0e-96	347	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
651663210	305	23.05	8	248	63	250	2.0e-20	93.5	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
651663211	231	40.62	9	229	4	227	3.0e-25	108	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
651663213	426	28.01	61	424	2	363	4.0e-55	209	COG0247	Fe-S oxidoreductase	388
651663218	110	42.31	1	103	1	101	7.0e-18	82.4	COG0633	Ferredoxin	102
651663219	345	39.89	1	344	4	352	3.0e-98	351	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
651663221	342	51.31	1	342	75	417	3.0e-125	441	COG0014	Gamma-glutamyl phosphate reductase	417
651663223	120	24.37	19	120	25	143	3.0e-05	40.7	COG3296	Uncharacterized conserved protein, Tic20 family	143
651663227	408	36.48	32	408	1	392	2.0e-77	283	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
651663231	435	60.14	7	427	2	420	0.0e+00	644	COG0499	S-adenosylhomocysteine hydrolase	420
651663232	166	27.81	1	166	40	208	2.0e-12	65.7	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
651663234	146	29.01	11	141	7	135	5.0e-17	80.3	COG5502	Uncharacterized conserved protein, DUF2267 family	135
651663238	347	55.16	3	337	2	334	1.0e-113	403	COG0136	Aspartate-semialdehyde dehydrogenase	334
651663243	298	44.69	24	293	1	268	1.0e-72	266	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
651663244	150	40.14	4	150	14	160	8.0e-34	136	COG0835	Chemotaxis signal transduction protein	165
651663248	106	23.08	6	92	6	96	9.0e-04	35.4	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
651663250	678	36.04	6	369	4	363	1.0e-85	311	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
651663251	427	38.53	11	424	14	460	4.0e-76	278	COG5267	Uncharacterized conserved protein, DUF1800 family	496
651663252	424	44.86	19	411	1	394	3.0e-96	345	COG0019	Diaminopimelate decarboxylase	394
651663255	338	26.32	19	338	4	315	5.0e-33	135	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651663256	295	24.01	26	295	101	378	6.0e-09	54.8	COG2814	Predicted arabinose efflux permease, MFS family	394
651663258	638	57	333	637	38	342	1.0e-94	341	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
651663262	204	37.13	1	202	1	200	6.0e-49	187	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
651663263	169	53.5	10	166	1	157	5.0e-45	173	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
651663264	253	58.09	5	245	1	241	4.0e-96	344	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
651663267	257	43.85	4	257	3	262	9.0e-61	227	COG0300	Short-chain dehydrogenase	265
651663269	185	48.65	1	184	1	182	4.0e-47	181	COG2096	Cob(I)alamin adenosyltransferase	184
651663270	295	33.45	6	291	13	297	1.0e-51	196	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
651663273	113	50	1	94	2	94	5.0e-27	112	COG0776	Bacterial nucleoid DNA-binding protein	94
651663274	212	37.5	5	212	3	203	7.0e-28	117	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
651663276	447	31.09	142	446	2	313	4.0e-38	152	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651663277	317	35.53	1	317	1	315	6.0e-34	138	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651663278	374	56.79	9	369	1	361	0.0e+00	487	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
651663279	405	47.61	2	404	8	424	2.0e-123	435	COG0124	Histidyl-tRNA synthetase	429
651663280	352	58.22	1	351	3	361	3.0e-129	455	COG0216	Protein chain release factor A	363
651663281	280	43.8	6	272	5	273	4.0e-51	195	COG2890	Methylase of polypeptide chain release factors	280
651663283	229	23.29	7	206	13	227	3.0e-11	62.4	COG2365	Protein tyrosine/serine phosphatase	249
651663287	101	34.38	5	98	1	96	2.0e-05	40.6	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
651663288	250	60.8	1	250	31	280	2.0e-100	358	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
651663290	304	55.78	1	303	19	321	0.0e+00	463	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
651663292	208	31.31	3	197	12	208	3.0e-22	98.4	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
651663295	861	30.44	17	685	2	640	0.0e+00	521	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
651663301	312	47.19	15	312	11	309	4.0e-99	354	COG0379	Quinolinate synthase	324
651663306	190	48.57	20	190	3	172	1.0e-35	143	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
651663307	334	36.25	6	332	5	332	3.0e-76	278	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
651663316	293	40.94	45	290	1	251	1.0e-40	160	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651663318	338	20.63	51	327	21	294	3.0e-37	149	COG0714	MoxR-like ATPase	329
651663320	289	43.01	1	270	48	333	4.0e-61	228	COG3376	High-affinity nickel permease	342
651663321	280	34.28	1	280	52	329	3.0e-49	188	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
651663325	372	50.67	4	372	1	367	2.0e-103	369	COG1109	Phosphomannomutase	464
651663326	224	43.72	1	211	20	233	5.0e-49	187	COG0688	Phosphatidylserine decarboxylase	239
651663330	348	42.82	5	348	2	356	6.0e-90	324	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
651663332	245	34.44	4	244	1	235	2.0e-40	159	COG2188	DNA-binding transcriptional regulator, GntR family	236
651663333	341	25	32	308	3	268	3.0e-20	92.9	COG1216	Glycosyltransferase, GT2 family	305
651663344	68	41.18	1	67	3	70	1.0e-07	48.5	COG2608	Copper chaperone CopZ	71
651663346	228	35.39	6	228	72	309	3.0e-31	128	COG0142	Geranylgeranyl pyrophosphate synthase	322
651663351	304	24.32	1	250	1	256	1.0e-18	87.3	COG4233	Thiol-disulfide interchange protein, contains DsbC and DsbD domains	273
651663354	294	20.7	3	285	25	263	5.0e-07	48.8	COG1652	Nucleoid-associated protein YgaU, contains BON and LysM domains	269
651663360	129	30.6	2	129	12	145	5.0e-12	63.4	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
651663371	409	34.26	90	395	63	381	1.0e-33	137	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651663372	213	35.44	16	211	8	206	3.0e-23	102	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
651663373	493	20.52	10	437	16	458	4.0e-18	86.3	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
651663376	308	34.75	1	258	7	264	2.0e-39	156	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
651663378	358	22.33	24	287	20	328	5.0e-08	52.6	COG3146	Predicted N-acyltransferase	387
651663379	394	18.86	4	393	3	374	4.0e-11	63.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651663385	327	44.17	1	324	3	325	2.0e-82	299	COG1171	Threonine dehydratase	347
651663387	289	34.4	1	282	3	261	4.0e-52	198	COG1291	Flagellar motor component MotA	266
651663388	167	45.83	1	167	2	168	2.0e-41	161	COG1247	L-amino acid N-acyltransferase YncA	169
651663389	742	34.48	28	722	21	709	0.0e+00	537	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
651663390	476	19.49	54	402	14	294	2.0e-08	54.2	COG1566	Multidrug resistance efflux pump	352
651663392	263	38.61	8	253	1	251	6.0e-35	141	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651663393	390	37.56	1	390	1	392	6.0e-74	271	COG0183	Acetyl-CoA acetyltransferase	392
651663394	154	34.19	1	154	8	159	8.0e-27	112	COG2030	Acyl dehydratase	159
651663395	326	46.01	1	324	1	315	2.0e-89	322	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
651663398	327	25.23	4	325	13	322	1.0e-19	90.6	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651663399	344	35.94	17	334	1	316	1.0e-42	167	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651663401	146	24.24	6	104	15	111	4.0e-09	54.4	COG1917	Cupin domain protein related to quercetin dioxygenase	131
651663404	364	29.25	8	300	1	266	2.0e-42	166	COG1018	Ferredoxin-NADP reductase	266
651663407	386	25.21	17	369	2	323	1.0e-27	117	COG1275	Tellurite resistance protein TehA and related permeases	329
651663408	333	49.39	1	327	1	322	4.0e-90	324	COG2376	Dihydroxyacetone kinase	323
651663410	254	51.35	7	225	4	225	1.0e-71	263	COG1131	ABC-type multidrug transport system, ATPase component	293
651663411	374	32.69	165	372	75	282	8.0e-20	91.5	COG0842	ABC-type multidrug transport system, permease component	286
651663412	368	30.62	161	368	76	284	3.0e-19	90	COG0842	ABC-type multidrug transport system, permease component	286
651663413	533	40.11	1	527	26	560	0.0e+00	479	COG1151	Hydroxylamine reductase (hybrid-cluster protein)	576
651663414	336	32.55	119	329	25	222	3.0e-34	139	COG0543	NAD(P)H-flavin reductase	252
651663415	150	44.36	1	131	1	133	3.0e-30	124	COG1959	DNA-binding transcriptional regulator, IscR family	150
651663416	376	24.28	30	366	39	375	3.0e-16	79.6	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
651663418	410	30.2	6	402	2	372	7.0e-33	135	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651663419	353	22.09	22	337	52	374	8.0e-07	48.4	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
651663420	336	26.65	1	336	3	342	4.0e-22	99.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651663421	813	35.13	12	807	1	731	0.0e+00	463	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
651663422	280	31.71	157	279	2	124	4.0e-16	78.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
651663423	207	30.88	1	200	4	201	6.0e-41	160	COG0288	Carbonic anhydrase	207
651663424	270	54.47	12	267	1	257	1.0e-87	316	COG0413	Ketopantoate hydroxymethyltransferase	268
651663425	204	49.04	1	204	1	205	8.0e-52	196	COG0522	Ribosomal protein S4 or related protein	205
651663428	191	35.96	23	191	1	177	6.0e-26	110	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
651663429	150	35.61	1	132	4	135	8.0e-28	116	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
651663430	270	38.1	17	265	34	283	1.0e-43	170	COG3176	Putative hemolysin	292
651663431	169	45.22	11	164	3	157	2.0e-34	138	COG3814	Uncharacterized protein	157
651663432	548	37.94	44	353	2	297	6.0e-79	288	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
651663433	131	23.57	7	125	2	136	2.0e-08	51.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
651663435	175	47.43	1	175	4	174	5.0e-35	140	COG2180	Nitrate reductase assembly protein NarJ, required for insertion of molybdenum cofactor	179
651663436	508	73.35	1	497	1	499	0.0e+00	883	COG1140	Nitrate reductase beta subunit	513
651663437	1244	69.8	1	1231	1	1227	0.0e+00	2021	COG5013	Nitrate reductase alpha subunit	1227
651663438	240	25.47	19	224	1	212	8.0e-21	94.1	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
651663440	368	42.47	12	333	28	355	3.0e-75	275	COG1858	Cytochrome c peroxidase	364
651663441	196	32.97	9	189	1	181	6.0e-26	110	COG0431	NAD(P)H-dependent FMN reductase	184
651663442	341	33.65	11	327	5	309	5.0e-65	241	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
651663443	303	36.95	1	292	1	291	3.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
651663445	172	51.52	8	172	1	163	7.0e-44	169	COG0440	Acetolactate synthase, small subunit	163
651663446	593	49.56	10	572	3	549	0.0e+00	625	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
651663451	547	29.97	69	440	22	390	3.0e-40	160	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
651663452	341	38.44	8	337	2	308	2.0e-59	222	COG2017	Galactose mutarotase or related enzyme	308
651663453	343	67.49	1	280	5	279	3.0e-89	321	COG0468	RecA/RadA recombinase	279
651663458	560	39.38	115	273	2	157	1.0e-21	98.6	COG3436	Transposase	157
651663461	383	43.9	2	377	17	389	9.0e-99	353	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
651663462	719	29.03	171	712	66	618	8.0e-73	268	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
651663465	113	25.77	21	109	18	114	3.0e-03	34.2	COG5442	Flagellar biosynthesis regulator FlaF	115
651663466	132	28.46	2	128	3	128	4.0e-12	63.8	COG5443	Flagellar biosynthesis regulator FlbT	148
651663467	577	19.38	67	479	10	432	5.0e-23	103	COG5421	Transposase	480
651663468	295	22.14	7	286	2	279	4.0e-13	68.9	COG1344	Flagellin and related hook-associated protein FlgL	360
651663472	184	34.64	28	175	50	202	8.0e-25	107	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
651663474	491	20.89	4	466	2	473	4.0e-08	53.2	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
651663475	228	45.5	12	222	10	211	1.0e-67	249	COG0321	Lipoate-protein ligase B	221
651663477	497	54.48	1	431	13	432	0.0e+00	546	COG0281	Malic enzyme	432
651663479	228	49.77	2	222	1	219	6.0e-61	227	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
651663480	400	44.28	1	400	1	392	7.0e-81	294	COG0183	Acetyl-CoA acetyltransferase	392
651663481	173	37.84	4	173	45	226	2.0e-28	118	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
651663482	234	44.1	6	234	5	225	2.0e-55	209	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
651663483	398	28.1	6	388	2	387	2.0e-45	177	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
651663484	728	76.71	1	728	12	730	0.0e+00	1193	COG0376	Catalase (peroxidase I)	730
651663485	330	42.99	19	330	1	313	1.0e-53	203	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651663486	339	32.2	1	319	2	312	3.0e-39	156	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651663488	250	37.07	3	242	1	251	5.0e-32	131	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651663489	272	28.1	1	272	8	278	7.0e-44	170	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
651663491	306	19.09	33	256	10	222	4.0e-08	52.3	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
651663492	132	28.57	21	115	24	117	1.0e-03	35.8	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
651663493	434	37.88	15	425	20	447	2.0e-102	366	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
651663495	182	28.69	14	135	1	122	2.0e-12	65.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
651663496	161	48	2	150	1	150	1.0e-47	182	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
651663497	760	22.05	52	759	38	731	6.0e-55	209	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
651663498	390	29.62	1	263	3	282	7.0e-21	95.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
651663499	442	23.93	1	436	6	433	4.0e-34	139	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
651663500	292	38.83	2	290	1	290	1.0e-53	203	COG1175	ABC-type sugar transport system, permease component	295
651663501	278	35.4	6	276	11	278	1.0e-46	180	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
651663502	356	51.59	1	347	1	337	2.0e-119	422	COG3839	ABC-type sugar transport system, ATPase component	338
651663503	196	26.67	22	184	20	176	4.0e-17	81.4	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
651663504	289	30.93	1	285	1	289	1.0e-24	107	COG0583	DNA-binding transcriptional regulator, LysR family	297
651663505	218	26.95	46	212	9	155	2.0e-15	75.7	COG1225	Peroxiredoxin	157
651663507	196	41.9	2	175	31	209	5.0e-34	137	COG4117	Thiosulfate reductase cytochrome b subunit	221
651663508	239	32.5	7	238	4	243	8.0e-40	157	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
651663511	294	31.4	11	293	4	291	8.0e-32	130	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
651663512	504	37.18	21	398	4	384	1.0e-63	237	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
651663514	668	37.03	33	663	29	604	3.0e-129	456	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
651663515	615	26.94	2	608	100	772	8.0e-108	385	COG4993	Glucose dehydrogenase	773
651663516	289	18.8	5	260	1	247	2.0e-13	70	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
651663517	249	40.59	22	122	9	109	4.0e-18	85.2	COG4654	Cytochrome c551/c552	110
651663518	190	28.36	27	160	8	133	8.0e-15	73.5	COG3791	Uncharacterized conserved protein	133
651663519	369	67.21	1	369	1	366	0.0e+00	565	COG1062	Zn-dependent alcohol dehydrogenase	366
651663520	701	21.74	1	699	10	768	4.0e-32	133	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
651663521	468	40.86	8	468	2	456	6.0e-82	298	COG0277	FAD/FMN-containing dehydrogenase	459
651663522	552	23.32	6	511	110	680	4.0e-56	212	COG4993	Glucose dehydrogenase	773
651663524	557	41.68	12	557	9	503	9.0e-128	450	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
651663525	227	38.64	9	220	24	242	2.0e-43	169	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
651663526	582	40.7	29	582	13	587	0.0e+00	469	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
651663527	263	49.8	7	248	1	241	7.0e-61	227	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
651663531	412	21.67	97	388	6	303	1.0e-06	47.6	COG0582	Integrase	309
651663535	226	29.82	9	226	15	226	2.0e-34	139	COG3701	Type IV secretory pathway, TrbF components	228
651663536	613	25.18	26	445	29	419	5.0e-24	106	COG3846	Type IV secretory pathway, TrbL components	452
651663537	247	30	5	220	12	231	1.0e-16	80.1	COG5314	Conjugal transfer/entry exclusion protein	252
651663538	841	27.02	1	803	4	783	1.0e-111	398	COG3451	Type IV secretory pathway, VirB4 component	796
651663540	289	43.49	2	286	52	333	6.0e-66	244	COG4962	Pilus assembly protein, ATPase of CpaF family	355
651663542	719	31.47	1	598	1	552	4.0e-117	415	COG0550	DNA topoisomerase IA	570
651663553	526	37.62	106	402	3	295	2.0e-57	216	COG4227	Antirestriction protein ArdC	316
651663556	451	18.92	5	441	87	543	1.0e-09	58	COG2831	Hemolysin activation/secretion protein	554
651663558	614	29.22	13	585	83	645	2.0e-114	406	COG0209	Ribonucleotide reductase alpha subunit	696
651663566	778	29.94	15	675	2	595	2.0e-95	344	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
651663568	84	34.78	5	73	1	68	2.0e-06	44.1	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
651663569	390	23.37	105	372	5	290	2.0e-13	70.6	COG4974	Site-specific recombinase XerD	300
651663570	86	34.48	25	82	13	70	3.0e-04	36.4	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
651663574	269	46.53	13	257	6	250	3.0e-66	245	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
651663575	505	49.61	1	504	11	514	0.0e+00	510	COG0578	Glycerol-3-phosphate dehydrogenase	532
651663576	499	58.4	1	499	3	498	0.0e+00	721	COG0554	Glycerol kinase	499
651663577	316	41.83	11	273	2	239	7.0e-48	184	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
651663579	546	36.36	9	546	8	530	1.0e-108	387	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
651663580	499	35.31	19	488	7	452	1.0e-99	357	COG2079	2-methylcitrate dehydratase PrpD	453
651663581	383	46.63	4	382	8	390	1.0e-114	406	COG0372	Citrate synthase	390
651663582	304	50.87	10	294	2	287	8.0e-82	297	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
651663583	391	45.9	13	391	3	391	2.0e-79	289	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
651663584	365	24.46	4	325	2	257	2.0e-28	120	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
651663585	299	48.97	2	292	1	285	2.0e-73	269	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
651663586	568	33.9	26	546	1	524	8.0e-114	404	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
651663587	231	37.93	1	231	3	200	4.0e-47	181	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
651663588	383	43.14	25	371	1	338	1.0e-93	336	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
651663589	281	42.7	2	265	2	267	5.0e-60	224	COG2240	Pyridoxal/pyridoxine/pyridoxamine kinase	281
651663592	439	52.43	29	437	1	400	4.0e-111	395	COG0004	Ammonia channel protein AmtB	409
651663593	300	42.07	2	298	3	309	8.0e-45	174	COG0524	Sugar or nucleoside kinase, ribokinase family	311
651663594	143	42.96	1	142	1	142	3.0e-36	144	COG4154	L-fucose mutarotase/ribose pyranase, RbsD/FucU family	144
651663595	147	55.07	5	141	4	141	3.0e-35	140	COG5579	Uncharacterized protein, DUF1810 family	143
651663597	494	42.35	14	490	1	434	9.0e-121	427	COG0305	Replicative DNA helicase	435
651663599	357	42.61	5	353	6	357	5.0e-95	341	COG0787	Alanine racemase	360
651663600	260	47.04	7	259	11	263	2.0e-56	213	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
651663601	261	48.21	8	258	6	256	6.0e-82	297	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
651663603	333	44.55	7	332	1	326	4.0e-81	294	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
651663604	413	23.1	54	395	13	356	5.0e-19	89.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
651663605	210	36.28	3	111	1	112	1.0e-13	69.6	COG2863	Cytochrome c553	121
651663608	279	37.59	1	276	2	287	1.0e-53	203	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
651663610	255	34.18	17	251	3	229	6.0e-48	184	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
651663612	218	25.29	43	213	2	174	4.0e-12	65	COG1076	DnaJ-domain-containing proteins 1	174
651663613	220	43.67	2	213	26	254	2.0e-58	218	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
651663615	815	60	27	585	6	556	0.0e+00	872	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
651663616	299	38.83	2	272	1	267	3.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
651663617	313	30.32	3	311	1	306	4.0e-31	128	COG0679	Predicted permease	311
651663618	1069	35.57	805	1056	6	256	1.0e-48	188	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
651663622	131	23.08	4	107	2	105	1.0e-06	45.8	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
651663626	190	43.4	9	165	4	161	5.0e-41	160	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
651663628	99	25	7	86	1	80	1.0e-04	38	COG0236	Acyl carrier protein	80
651663630	278	28.63	23	219	11	234	4.0e-13	69.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
651663631	296	40.14	4	278	65	334	5.0e-66	244	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
651663632	353	47.37	35	336	4	288	2.0e-83	303	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
651663634	250	47.3	24	239	5	226	5.0e-72	264	COG1136	ABC-type lipoprotein export system, ATPase component	226
651663635	107	29.17	2	97	3	97	3.0e-09	53.3	COG1993	PII-like signaling protein	109
651663636	125	43.2	1	125	1	125	6.0e-20	89.5	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
651663637	414	33.18	12	411	4	422	2.0e-46	180	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
651663638	541	26.86	125	541	1	419	9.0e-41	161	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
651663639	618	25.62	1	618	1	578	8.0e-79	288	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
651663640	285	44.93	68	281	1	226	3.0e-61	228	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
651663641	326	33.54	15	326	11	324	2.0e-50	193	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
651663644	130	21.43	5	128	2	138	5.0e-11	60.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
651663650	172	26.32	8	152	4	155	2.0e-11	62.3	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
651663651	559	46.61	5	541	1	530	0.0e+00	571	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
651663653	323	33.75	4	320	3	302	1.0e-58	220	COG1893	Ketopantoate reductase	307
651663654	438	37.39	1	434	83	525	2.0e-89	323	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
651663656	280	32.67	14	259	7	245	2.0e-41	163	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
651663657	466	40.38	2	460	9	466	2.0e-120	425	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
651663658	326	42.14	1	313	1	315	3.0e-88	318	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
651663659	232	34.68	16	232	1	213	3.0e-39	155	COG3047	Outer membrane protein W	213
651663660	144	64.54	2	142	1	139	1.0e-49	188	COG0080	Ribosomal protein L11	141
651663661	230	63.16	1	226	1	228	6.0e-80	290	COG0081	Ribosomal protein L1	228
651663662	178	44.58	7	170	5	170	6.0e-32	130	COG0244	Ribosomal protein L10	175
651663663	127	64.57	1	127	2	124	8.0e-26	109	COG0222	Ribosomal protein L7/L12	124
651663665	1388	50.77	20	845	7	806	0.0e+00	896	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
651663666	123	73.17	1	123	7	129	7.0e-47	178	COG0048	Ribosomal protein S12	129
651663667	158	66	2	151	1	148	4.0e-56	210	COG0049	Ribosomal protein S7	148
651663668	395	80.3	1	395	1	394	0.0e+00	696	COG0050	Translation elongation factor EF-Tu, a GTPase	394
651663669	102	73.53	1	102	1	102	3.0e-38	149	COG0051	Ribosomal protein S10	104
651663670	224	52.29	2	216	1	218	2.0e-70	258	COG0087	Ribosomal protein L3	218
651663671	216	45.93	1	203	2	210	5.0e-48	184	COG0088	Ribosomal protein L4	214
651663672	113	61.96	21	110	1	92	3.0e-23	100	COG0089	Ribosomal protein L23	94
651663673	277	61.68	1	273	1	274	3.0e-105	374	COG0090	Ribosomal protein L2	275
651663674	92	61.96	1	91	1	92	1.0e-34	137	COG0185	Ribosomal protein S19	93
651663675	153	51.38	14	122	10	118	2.0e-24	104	COG0091	Ribosomal protein L22	120
651663676	225	62.04	12	225	1	216	4.0e-76	277	COG0092	Ribosomal protein S3	233
651663677	138	61.87	1	137	2	140	8.0e-47	179	COG0197	Ribosomal protein L16/L10AE	146
651663678	68	47.76	1	67	2	68	2.0e-09	53.7	COG0255	Ribosomal protein L29	69
651663679	90	61.64	1	73	6	78	5.0e-24	102	COG0186	Ribosomal protein S17	87
651663680	122	72.13	1	122	1	122	4.0e-45	173	COG0093	Ribosomal protein L14	122
651663681	106	57.55	1	105	1	104	1.0e-21	94.6	COG0198	Ribosomal protein L24	104
651663682	185	66.1	9	185	3	179	7.0e-74	269	COG0094	Ribosomal protein L5	180
651663683	101	52.46	41	101	1	61	6.0e-14	69.1	COG0199	Ribosomal protein S14	61
651663684	132	54.14	1	132	1	132	1.0e-44	171	COG0096	Ribosomal protein S8	132
651663685	177	50.85	1	176	1	176	6.0e-54	203	COG0097	Ribosomal protein L6P/L9E	178
651663686	120	53.91	8	120	12	125	1.0e-28	118	COG0256	Ribosomal protein L18	125
651663687	189	59.54	6	178	8	180	5.0e-55	207	COG0098	Ribosomal protein S5	181
651663688	64	43.64	8	62	1	55	2.0e-10	57.4	COG1841	Ribosomal protein L30/L7E	55
651663689	161	47.77	1	152	1	151	4.0e-27	114	COG0200	Ribosomal protein L15	152
651663690	449	50	13	440	9	432	1.0e-117	416	COG0201	Preprotein translocase subunit SecY	436
651663691	224	40.65	1	214	1	178	1.0e-49	189	COG0563	Adenylate kinase or related kinase	178
651663692	125	65.29	1	121	1	121	4.0e-41	160	COG0099	Ribosomal protein S13	121
651663693	130	64.62	1	130	1	129	1.0e-44	171	COG0100	Ribosomal protein S11	129
651663694	339	52.98	12	330	3	317	3.0e-99	355	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
651663695	146	65.52	1	116	1	116	1.0e-43	169	COG0203	Ribosomal protein L17	116
651663696	554	22.57	35	552	55	590	5.0e-67	249	COG1164	Oligoendopeptidase F	598
651663697	132	36.59	6	128	6	123	2.0e-13	68	COG3788	Uncharacterized membrane protein YecN, MAPEG domain	131
651663698	158	34.29	20	157	16	155	9.0e-20	89.5	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
651663699	289	43.55	8	287	1	287	6.0e-53	201	COG0581	ABC-type phosphate transport system, permease component	292
651663700	324	40.45	7	317	21	305	4.0e-52	198	COG0573	ABC-type phosphate transport system, permease component	310
651663701	359	32.3	1	347	3	318	2.0e-44	173	COG0226	ABC-type phosphate transport system, periplasmic component	318
651663704	579	40.07	12	578	5	567	1.0e-119	424	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
651663705	491	19.53	8	322	2	344	2.0e-13	70.6	COG2814	Predicted arabinose efflux permease, MFS family	394
651663710	332	38.68	15	257	1	230	5.0e-49	188	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
651663712	336	35.78	7	331	4	318	2.0e-47	183	COG0385	Predicted Na+-dependent transporter	319
651663713	259	35.63	24	258	1	245	1.0e-23	103	COG0583	DNA-binding transcriptional regulator, LysR family	297
651663717	345	54.87	32	338	5	304	1.0e-94	339	COG0492	Thioredoxin reductase	305
651663718	171	40.79	21	171	4	154	9.0e-29	119	COG1522	DNA-binding transcriptional regulator, Lrp family	154
651663722	386	42.77	79	381	6	315	2.0e-74	273	COG1171	Threonine dehydratase	347
651663723	248	22.27	24	248	1	229	9.0e-20	90.6	COG1794	Aspartate/glutamate racemase	230
651663724	253	34.25	1	252	1	251	2.0e-36	146	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651663725	304	31.35	5	298	2	297	5.0e-32	131	COG0583	DNA-binding transcriptional regulator, LysR family	297
651663726	85	37.66	9	85	4	80	1.0e-09	54.7	COG5302	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid	80
651663729	653	46.44	11	653	3	635	0.0e+00	774	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
651663730	212	44.84	1	210	1	222	2.0e-54	205	COG0283	Cytidylate kinase	222
651663731	445	43.12	14	441	9	428	2.0e-105	376	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
651663733	409	53	11	409	3	396	4.0e-125	441	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
651663734	279	21.25	20	279	13	282	2.0e-08	52.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
651663735	283	29.86	6	276	12	286	4.0e-28	118	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
651663736	773	39.94	40	737	4	705	0.0e+00	558	COG0557	Exoribonuclease R	706
651663737	530	32.44	154	442	69	364	9.0e-51	195	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
651663738	55	48.94	7	53	4	50	2.0e-08	51	COG0267	Ribosomal protein L33	50
651663739	379	42.15	1	379	1	379	2.0e-100	359	COG0763	Lipid A disaccharide synthetase	381
651663740	291	28.62	1	280	1	266	2.0e-30	126	COG0388	Predicted amidohydrolase	274
651663742	575	30.17	333	446	35	143	6.0e-09	56.1	COG2010	Cytochrome c, mono- and diheme variants	150
651663746	518	19.26	5	518	57	554	2.0e-26	114	COG2831	Hemolysin activation/secretion protein	554
651663747	259	24.27	18	236	47	284	6.0e-07	48.2	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
651663748	708	23.4	337	704	6	374	3.0e-16	80.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651663749	219	18.22	2	218	9	233	2.0e-06	45.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
651663750	791	37.11	19	784	3	731	0.0e+00	511	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
651663751	625	43.52	50	613	1	573	0.0e+00	605	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
651663752	359	50.75	11	343	6	337	1.0e-96	346	COG0206	Cell division GTPase FtsZ	338
651663753	435	41.13	34	404	10	379	3.0e-98	352	COG0849	Cell division ATPase FtsA	418
651663754	292	28.36	15	283	4	268	5.0e-22	98.6	COG1589	Cell division septal protein FtsQ	269
651663755	301	40.13	2	297	3	316	8.0e-76	277	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
651663757	533	38.99	8	385	73	467	4.0e-78	286	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
651663760	434	18.97	53	418	48	383	6.0e-08	52.5	COG2814	Predicted arabinose efflux permease, MFS family	394
651663763	497	42.24	4	484	1	472	1.0e-129	456	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
651663764	430	23.58	25	425	4	409	2.0e-42	167	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
651663766	600	29.31	158	592	1	443	9.0e-84	304	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
651663767	162	35.09	50	162	6	112	1.0e-13	69.9	COG1416	Intracellular sulfur oxidation protein, DsrE/DsrF family	112
651663768	265	25.09	27	260	19	282	1.0e-09	57.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
651663769	611	40.91	13	607	98	709	4.0e-123	435	COG2217	Cation transport ATPase	713
651663771	258	50	7	258	3	254	8.0e-80	290	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
651663772	606	44.37	154	605	5	445	1.0e-118	420	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
651663773	471	31.49	196	471	23	327	4.0e-51	196	COG0280	Phosphotransacetylase	327
651663774	116	35.64	6	106	14	114	2.0e-13	68.1	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
651663776	338	30.67	4	325	1	303	3.0e-33	135	COG3547	Transposase	303
651663778	904	22.88	355	904	1	577	6.0e-23	103	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
651663780	218	33.01	15	218	21	227	1.0e-34	140	COG4291	Uncharacterized membrane protein	228
651663781	547	48.15	8	545	4	532	0.0e+00	574	COG1069	Ribulose kinase	544
651663782	313	33.12	4	312	1	310	2.0e-45	176	COG0524	Sugar or nucleoside kinase, ribokinase family	311
651663783	299	26.44	26	227	5	206	3.0e-23	102	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
651663784	436	24.83	1	432	5	432	1.0e-39	157	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
651663785	327	37.68	43	323	7	289	4.0e-50	191	COG1175	ABC-type sugar transport system, permease component	295
651663786	276	37.37	1	276	1	281	2.0e-44	172	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
651663787	365	53.82	1	353	1	338	2.0e-122	432	COG3839	ABC-type sugar transport system, ATPase component	338
651663788	257	42.75	7	255	2	251	4.0e-48	185	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651663789	257	38.31	3	253	1	249	3.0e-37	148	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651663790	499	56.38	7	491	4	483	0.0e+00	685	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
651663791	604	40.03	8	603	4	571	0.0e+00	601	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
651663792	211	50.48	3	211	2	210	1.0e-53	202	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
651663793	447	21.63	12	426	20	387	3.0e-12	66.8	COG2814	Predicted arabinose efflux permease, MFS family	394
651663794	424	22.58	6	422	2	423	2.0e-23	104	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
651663795	213	46.62	1	147	1	146	7.0e-35	140	COG3427	Carbon monoxide dehydrogenase subunit G	146
651663796	300	27.39	1	290	6	284	6.0e-29	121	COG0714	MoxR-like ATPase	329
651663797	403	46.37	7	390	9	394	2.0e-81	296	COG3552	Uncharacterized conserved protein, contains von Willebrand factor type A (vWA) domain	395
651663803	170	21.02	22	170	7	159	1.0e-07	49.5	COG1580	Flagellar basal body-associated protein FliL	159
651663804	1005	37.43	1	977	32	1064	0.0e+00	924	COG0587	DNA polymerase III, alpha subunit	1139
651663806	269	43.36	1	256	1	245	1.0e-79	289	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
651663807	293	31.32	31	293	2	263	3.0e-36	146	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
651663809	400	48.4	7	400	2	393	4.0e-116	412	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
651663810	628	29.7	26	591	94	649	2.0e-115	410	COG0209	Ribonucleotide reductase alpha subunit	696
651663811	338	32.21	20	334	20	342	2.0e-80	292	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
651663814	266	38.81	1	262	1	268	3.0e-44	172	COG0388	Predicted amidohydrolase	274
651663816	223	40.44	1	223	2	211	6.0e-35	140	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
651663817	311	48.08	1	303	3	310	3.0e-99	355	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
651663818	428	40.76	7	427	2	420	3.0e-97	349	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
651663819	192	46.94	1	188	4	199	6.0e-38	150	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
651663820	373	38.27	1	367	3	347	3.0e-83	302	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
651663821	891	47.75	2	572	1	556	0.0e+00	615	COG0550	DNA topoisomerase IA	570
651663823	348	37.6	1	347	104	468	7.0e-66	244	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
651663824	391	60.89	11	391	7	379	0.0e+00	477	COG3970	Fumarylacetoacetate (FAA) hydrolase family protein	379
651663825	210	46.27	4	203	1	201	7.0e-41	160	COG1279	Arginine exporter protein ArgO	202
651663826	295	28.81	2	295	1	297	1.0e-17	83.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
651663827	284	41.2	22	283	14	280	2.0e-41	162	COG5473	Uncharacterized membrane protein	290
651663828	292	31.56	8	292	2	313	7.0e-53	200	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
651663829	293	31.29	1	291	6	290	9.0e-31	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
651663830	314	52.63	9	309	3	298	6.0e-90	324	COG3246	Uncharacterized conserved protein, DUF849 family	298
651663831	312	34.89	1	234	4	234	4.0e-50	192	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
651663832	362	28.25	13	322	9	317	6.0e-32	131	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651663836	281	43.59	10	277	1	261	3.0e-69	255	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
651663837	425	43.78	1	425	15	444	0.0e+00	463	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
651663838	476	46.82	5	474	1	467	0.0e+00	467	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
651663839	265	28.14	10	263	59	317	2.0e-40	159	COG0616	Periplasmic serine protease, ClpP class	317
651663840	141	44.14	2	140	3	144	1.0e-27	115	COG5458	Uncharacterized protein	144
651663841	770	38.6	8	766	8	731	0.0e+00	537	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
651663845	172	27.84	1	168	1	172	1.0e-11	63.1	COG5468	Predicted secreted (periplasmic) protein	172
651663846	864	46.75	7	862	1	814	0.0e+00	952	COG0495	Leucyl-tRNA synthetase	814
651663850	313	41.37	40	312	2	263	3.0e-53	202	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
651663851	684	43.45	8	681	8	667	0.0e+00	613	COG1331	Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains	667
651663852	116	42.86	55	110	3	58	1.0e-11	61.5	COG3411	(2Fe-2S) ferredoxin	64
651663853	433	39.87	3	433	1	454	2.0e-112	399	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
651663854	576	50.57	6	572	3	618	0.0e+00	758	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
651663855	217	42.44	20	188	12	181	8.0e-40	157	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
651663856	263	41.57	3	255	2	253	7.0e-59	220	COG1192	Cellulose biosynthesis protein BcsQ	259
651663857	292	37.74	32	284	1	240	2.0e-34	139	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
651663858	492	35.24	1	459	1	467	1.0e-88	320	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
651663860	131	33.07	1	125	6	131	7.0e-18	82.9	COG1917	Cupin domain protein related to quercetin dioxygenase	131
651663861	329	23.71	1	323	1	309	2.0e-31	129	COG0451	Nucleoside-diphosphate-sugar epimerase	314
651663862	249	32.65	3	245	6	246	8.0e-35	140	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
651663863	389	30.33	1	388	1	392	6.0e-63	235	COG0183	Acetyl-CoA acetyltransferase	392
651663864	1139	48	5	1136	3	1138	0.0e+00	1173	COG0587	DNA polymerase III, alpha subunit	1139
651663866	311	42.81	1	302	75	377	3.0e-82	298	COG1454	Alcohol dehydrogenase, class IV	377
651663868	484	43.27	1	484	51	528	0.0e+00	481	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
651663869	222	23.29	10	222	1	215	5.0e-08	51.5	COG2202	PAS domain	232
651663876	730	22.64	446	730	97	379	9.0e-12	66.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651663879	272	45.9	5	272	2	258	1.0e-69	256	COG1091	dTDP-4-dehydrorhamnose reductase	281
651663880	184	50.28	1	177	2	173	4.0e-55	207	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
651663881	293	54.9	3	288	1	283	3.0e-102	364	COG1209	dTDP-glucose pyrophosphorylase	286
651663882	331	54.49	6	328	27	337	7.0e-128	450	COG1088	dTDP-D-glucose 4,6-dehydratase	340
651663886	834	20.1	9	380	35	378	1.0e-08	56.3	COG1061	Superfamily II DNA or RNA helicase	442
651663887	614	22.41	7	460	67	491	8.0e-28	119	COG2189	Adenine specific DNA methylase Mod	590
651663888	665	23.22	17	665	10	658	1.0e-81	297	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
651663893	223	45.07	13	223	3	215	3.0e-57	215	COG2846	Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains	221
651663896	377	20.11	29	376	3	361	2.0e-15	77.4	COG1106	ATPase/GTPase, AAA15 family	371
651663899	178	47.1	33	169	13	147	5.0e-32	130	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
651663902	158	39.85	18	149	3	135	2.0e-29	121	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
651663903	95	48.42	1	95	1	95	6.0e-22	95.7	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
651663904	493	53.64	1	485	2	473	0.0e+00	481	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
651663905	487	55.6	7	484	1	482	0.0e+00	686	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
651663906	229	33.64	3	217	1	207	8.0e-32	130	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
651663907	126	38.14	27	123	14	101	1.0e-05	41.9	COG2863	Cytochrome c553	121
651663908	144	33.58	1	134	4	140	6.0e-20	90	COG2847	Copper(I)-binding protein	151
651663909	214	29.5	11	209	12	206	8.0e-30	123	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
651663910	505	20.84	1	500	1	498	7.0e-16	79	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
651663916	184	45.28	34	184	1	158	3.0e-42	164	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
651663917	169	47.8	7	165	4	157	1.0e-53	202	COG0669	Phosphopantetheine adenylyltransferase	159
651663918	910	49	7	900	1	804	0.0e+00	938	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
651663921	1024	24.65	595	1017	35	420	4.0e-33	137	COG4995	Uncharacterized conserved protein, contains CHAT domain	420
651663922	393	34.14	11	276	1	284	2.0e-48	186	COG0515	Serine/threonine protein kinase	384
651663924	123	42.86	8	123	15	132	3.0e-24	103	COG3474	Cytochrome c2	135
651663926	610	48.9	18	606	6	585	0.0e+00	692	COG0514	Superfamily II DNA helicase RecQ	590
651663927	227	31.92	8	213	1	213	7.0e-28	117	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
651663928	431	61.48	1	430	1	426	0.0e+00	565	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
651663929	887	36.79	11	878	9	858	0.0e+00	564	COG0308	Aminopeptidase N	859
651663930	726	25.26	431	719	2	288	4.0e-17	83.8	COG5006	Threonine/homoserine efflux transporter RhtA	292
651663930	726	54.46	62	357	6	308	8.0e-98	351	COG3146	Predicted N-acyltransferase	387
651663931	537	23.94	6	447	39	496	2.0e-23	104	COG0833	Amino acid permease	541
651663933	199	30.58	1	199	1	206	1.0e-22	99.9	COG0625	Glutathione S-transferase	211
651663934	353	35.08	12	331	2	309	8.0e-59	221	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
651663935	426	33.67	1	394	1	384	4.0e-65	242	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
651663936	324	45.73	1	324	1	326	4.0e-82	298	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
651663938	520	69.5	203	520	2	315	0.0e+00	533	COG0519	GMP synthase, PP-ATPase domain/subunit	315
651663939	221	35.45	15	219	17	233	3.0e-37	148	COG0412	Dienelactone hydrolase	236
651663940	164	22.42	1	162	1	157	4.0e-09	54.6	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
651663941	321	29.25	72	315	5	244	8.0e-23	101	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
651663942	457	40.73	7	380	3	381	4.0e-96	345	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
651663949	204	33.68	15	204	23	209	5.0e-26	111	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
651663951	135	29.77	1	130	46	176	5.0e-11	60.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
651663959	539	22.93	3	201	2	188	1.0e-13	71.7	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
651663964	137	31.5	1	127	2	124	1.0e-08	52.3	COG4113	Predicted nucleic acid-binding protein, contains PIN domain	134
651663966	725	24.35	11	199	2	177	4.0e-09	57.2	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
651663969	177	28.07	1	168	26	184	6.0e-25	107	COG0431	NAD(P)H-dependent FMN reductase	184
651663970	439	38.6	1	429	4	424	3.0e-77	282	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
651663971	140	41.03	1	117	1	117	2.0e-35	141	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
651663972	174	32.64	5	143	2	136	2.0e-26	111	COG0394	Protein-tyrosine-phosphatase	139
651663973	129	27.78	1	108	3	108	1.0e-08	51.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
651663975	863	23.18	78	844	55	765	5.0e-59	223	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
651663976	100	60.78	1	100	3	102	1.0e-28	118	COG5489	Uncharacterized conserved protein, DUF736 family	107
651663978	253	36.72	3	248	1	251	2.0e-33	136	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651663979	308	39.73	10	303	10	298	2.0e-53	203	COG2421	Acetamidase/formamidase	305
651663981	93	29.03	6	66	1	62	7.0e-04	35.7	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
651663984	179	41.51	15	173	14	170	4.0e-33	134	COG4959	Type IV secretory pathway, protease TraF	173
651663986	592	36.31	10	313	20	320	1.0e-46	181	COG3843	Type IV secretory pathway, VirD2 components (relaxase)	326
651663987	132	35.58	4	106	3	106	2.0e-17	81.7	COG0789	DNA-binding transcriptional regulator, MerR family	124
651663988	482	39.69	22	466	6	453	9.0e-111	394	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
651663993	472	29.89	11	472	1	449	3.0e-64	239	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
651663994	150	37.75	1	150	1	147	1.0e-27	115	COG3019	Uncharacterized conserved protein	149
651663996	862	29.71	452	853	170	569	2.0e-59	224	COG4232	Thiol:disulfide interchange protein	569
651663998	240	34.05	58	240	22	206	1.0e-37	150	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
651663999	186	33.06	37	156	4	122	9.0e-14	70.3	COG0526	Thiol-disulfide isomerase or thioredoxin	127
651664000	198	26.45	51	170	6	124	2.0e-09	55.7	COG0526	Thiol-disulfide isomerase or thioredoxin	127
651664002	215	37.56	1	191	1	194	1.0e-59	222	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
651664003	122	32.79	1	122	5	126	7.0e-19	86.2	COG2372	Copper-binding protein CopC (methionine-rich)	127
651664004	306	29.77	45	300	27	286	3.0e-16	79.2	COG1276	Putative copper export protein	289
651664005	395	26.97	44	304	11	272	1.0e-24	108	COG3336	Cytochrome c oxidase assembly factor CtaG	299
651664006	141	25	3	117	20	124	2.0e-08	51.8	COG0526	Thiol-disulfide isomerase or thioredoxin	127
651664007	538	57.31	22	537	2	517	0.0e+00	560	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
651664008	311	29.1	41	281	17	239	3.0e-44	172	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
651664009	187	23.2	45	165	5	126	8.0e-09	53.8	COG0526	Thiol-disulfide isomerase or thioredoxin	127
651664010	155	32.5	1	119	1	120	2.0e-21	95.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
651664012	573	48.6	19	549	4	522	0.0e+00	500	COG2217	Cation transport ATPase	713
651664013	332	49.52	9	314	1	300	9.0e-97	347	COG0031	Cysteine synthase	300
651664014	272	36.96	5	267	9	280	4.0e-58	218	COG0682	Prolipoprotein diacylglyceryltransferase	287
651664016	307	31.96	8	219	15	223	7.0e-22	98	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
651664017	241	46.52	5	232	1	227	3.0e-55	208	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
651664018	472	31.08	163	472	13	329	3.0e-37	149	COG0642	Signal transduction histidine kinase	336
651664019	91	38.89	1	90	1	89	1.0e-15	74.5	COG1937	DNA-binding transcriptional regulator, FrmR family	89
651664020	457	28.23	44	454	11	414	2.0e-38	153	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
651664022	394	25.13	2	382	18	394	3.0e-27	116	COG2814	Predicted arabinose efflux permease, MFS family	394
651664023	816	41.04	22	789	2	705	0.0e+00	607	COG2217	Cation transport ATPase	713
651664024	229	26.94	1	214	4	220	6.0e-06	44.5	COG0785	Cytochrome c biogenesis protein CcdA	220
651664025	71	30	1	70	1	70	3.0e-09	53.5	COG2608	Copper chaperone CopZ	71
651664026	161	36.84	5	117	1	113	5.0e-17	80.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
651664027	152	37.95	2	152	36	201	1.0e-21	96	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
651664033	142	24.24	10	139	1	132	1.0e-13	69.3	COG3335	Transposase	132
651664034	671	39.93	1	576	4	576	0.0e+00	548	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
651664036	335	41.39	11	304	36	333	8.0e-80	290	COG4962	Pilus assembly protein, ATPase of CpaF family	355
651664037	134	47.92	40	133	15	108	5.0e-17	80.3	COG3838	Type IV secretory pathway, VirB2 components (pilins)	108
651664038	90	43.02	4	86	5	90	5.0e-17	79.3	COG5268	Type IV secretory pathway, TrbD component	93
651664039	900	33.26	1	840	3	796	0.0e+00	592	COG3451	Type IV secretory pathway, VirB4 component	796
651664040	259	35.12	13	254	13	250	5.0e-30	124	COG5314	Conjugal transfer/entry exclusion protein	252
651664042	446	30.51	4	436	29	448	2.0e-42	167	COG3846	Type IV secretory pathway, TrbL components	452
651664043	236	46.93	1	228	1	228	2.0e-60	225	COG3701	Type IV secretory pathway, TrbF components	228
651664044	326	35.63	65	324	3	253	8.0e-48	184	COG3504	Type IV secretory pathway, VirB9 components	265
651664045	395	34.14	64	392	62	355	1.0e-53	204	COG2948	Type IV secretory pathway, VirB10 components	360
651664046	102	36.71	1	79	1	77	7.0e-09	52.3	COG5639	Uncharacterized protein	77
651664050	112	30	1	110	17	122	1.0e-06	44.7	COG3293	Transposase	124
651664051	416	41.65	14	400	3	381	2.0e-91	329	COG5659	SRSO17 transposase	385
651664052	418	30.32	20	394	23	369	6.0e-36	145	COG5659	SRSO17 transposase	385
651664053	568	22.63	1	184	23	196	2.0e-13	70.9	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
651664057	662	31.09	194	646	120	587	4.0e-58	219	COG0465	ATP-dependent Zn proteases	596
651664065	320	20.06	16	320	1	321	9.0e-38	150	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
651664071	310	33.77	4	305	3	297	4.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
651664072	303	40	1	292	1	295	4.0e-65	241	COG3781	Predicted membrane chloride channel, bestrophin family	306
651664073	232	46.33	20	196	2	176	5.0e-48	184	COG1510	DNA-binding transcriptional regulator GbsR, MarR family	177
651664074	469	42.04	7	452	4	455	4.0e-115	408	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
651664075	341	41.86	1	336	1	340	2.0e-66	246	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
651664076	158	40.96	1	158	3	167	3.0e-32	131	COG0629	Single-stranded DNA-binding protein	167
651664077	821	17.16	18	821	3	768	6.0e-26	113	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
651664078	465	47.31	1	464	4	464	0.0e+00	489	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
651664079	740	39.97	30	737	9	706	0.0e+00	566	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
651664080	487	47.64	1	484	1	460	0.0e+00	512	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
651664081	381	40.11	23	379	8	361	1.0e-87	317	COG3852	Signal transduction histidine kinase, nitrogen specific	363
651664082	353	45.65	25	343	6	323	8.0e-85	307	COG0042	tRNA-dihydrouridine synthase	323
651664083	172	61.04	13	166	1	154	4.0e-57	213	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
651664085	487	45.82	13	348	6	347	9.0e-101	361	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
651664086	138	36.92	5	133	4	132	1.0e-17	82.7	COG4852	Uncharacterized membrane protein	134
651664087	279	31.42	17	272	5	231	1.0e-42	166	COG0860	N-acetylmuramoyl-L-alanine amidase	231
651664089	308	36.99	1	305	7	316	2.0e-62	232	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
651664091	156	26.92	47	150	25	128	4.0e-12	64.2	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
651664092	330	32.82	7	326	1	304	4.0e-38	152	COG0524	Sugar or nucleoside kinase, ribokinase family	311
651664093	66	53.19	16	62	8	54	2.0e-06	43.7	COG3847	Flp pilus assembly protein, pilin Flp	58
651664094	275	30.42	3	234	4	236	1.0e-23	103	COG3745	Flp pilus assembly protein CpaB	276
651664096	445	56.4	62	405	17	355	7.0e-115	407	COG4962	Pilus assembly protein, ATPase of CpaF family	355
651664097	319	31.09	7	318	1	309	4.0e-31	129	COG4965	Flp pilus assembly protein TadB	309
651664098	307	29.81	2	307	8	318	9.0e-17	81.4	COG2064	Pilus assembly protein TadC	320
651664099	490	40.04	5	484	3	444	2.0e-122	432	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
651664100	199	27.36	1	105	1	105	2.0e-16	79.1	COG1544	Ribosome-associated translation inhibitor RaiA	110
651664101	794	25.5	19	794	69	859	0.0e+00	624	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
651664104	225	53.2	23	222	1	203	7.0e-67	247	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
651664105	389	29.74	17	379	24	406	1.0e-55	210	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
651664107	168	49.06	3	161	42	195	3.0e-42	164	COG3816	Uncharacterized protein	205
651664108	277	45.96	14	276	1	264	3.0e-53	202	COG0714	MoxR-like ATPase	329
651664109	164	31.5	42	163	2	117	4.0e-08	51	COG2105	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family	120
651664112	415	37.26	95	402	1	313	2.0e-49	189	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
651664113	410	21.94	2	410	1	459	3.0e-18	86.5	COG3349	Uncharacterized conserved protein, contains NAD-binding domain and a Fe-S cluster	485
651664114	290	36.94	19	281	15	281	2.0e-36	146	COG1562	Phytoene/squalene synthetase	288
651664115	278	23.94	15	268	19	271	3.0e-22	99.3	COG1562	Phytoene/squalene synthetase	288
651664116	375	23.21	3	348	22	355	4.0e-15	76.1	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
651664117	361	24.93	25	347	3	312	2.0e-31	130	COG0451	Nucleoside-diphosphate-sugar epimerase	314
651664119	84	50	1	81	1	82	1.0e-06	45	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
651664122	237	31.12	11	237	3	242	2.0e-22	99.3	COG1587	Uroporphyrinogen-III synthase	248
651664123	297	45.42	1	295	20	302	1.0e-76	280	COG0181	Porphobilinogen deaminase	307
651664124	377	50.33	16	320	2	298	5.0e-92	331	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
651664125	835	46.41	29	830	5	748	0.0e+00	785	COG0058	Glucan phosphorylase	750
651664126	423	50	10	417	1	386	0.0e+00	506	COG0448	ADP-glucose pyrophosphorylase	393
651664127	479	47.84	1	479	1	481	0.0e+00	488	COG0297	Glycogen synthase	487
651664128	1030	36.6	2	1016	1	1009	0.0e+00	838	COG0841	Multidrug efflux pump subunit AcrB	1009
651664129	1065	36.12	2	1049	1	1009	0.0e+00	844	COG0841	Multidrug efflux pump subunit AcrB	1009
651664130	386	33.95	1	376	4	365	6.0e-31	128	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
651664131	502	37.03	50	499	4	451	2.0e-54	206	COG1538	Outer membrane protein TolC	457
651664132	184	32.04	2	174	6	181	3.0e-20	91.8	COG0406	Broad specificity phosphatase PhoE	208
651664135	315	37.75	17	315	2	291	2.0e-61	229	COG3386	Sugar lactone lactonase YvrE	307
651664136	316	38.17	1	316	1	312	1.0e-39	156	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651664137	332	36.72	31	331	12	316	5.0e-40	158	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651664146	326	55.56	5	326	1	322	2.0e-116	411	COG0502	Biotin synthase or related enzyme	335
651664147	323	44.86	3	322	1	310	8.0e-83	300	COG1984	Allophanate hydrolase subunit 2	314
651664148	291	31.43	5	249	1	218	1.0e-51	196	COG2049	Allophanate hydrolase subunit 1	223
651664151	259	47.41	6	254	4	252	2.0e-81	295	COG1540	Lactam utilization protein B (function unknown)	252
651664152	301	31.97	3	293	1	289	3.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
651664153	383	19.49	10	313	45	319	1.0e-13	71.6	COG0687	Spermidine/putrescine-binding periplasmic protein	363
651664154	302	36.27	1	294	70	357	2.0e-63	236	COG3328	Transposase (or an inactivated derivative)	379
651664156	355	35.91	36	350	1	318	4.0e-58	219	COG0523	GTPase, G3E family	323
651664158	254	41.9	1	249	2	251	9.0e-41	160	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651664159	461	18.02	80	457	71	437	7.0e-08	52.1	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
651664160	245	40.64	3	241	2	249	3.0e-44	171	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651664162	168	36.91	11	159	10	158	5.0e-23	100	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
651664164	690	29.76	342	591	6	253	8.0e-39	155	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
651664168	257	32.09	1	254	2	266	6.0e-47	181	COG1018	Ferredoxin-NADP reductase	266
651664170	275	62.13	3	274	2	273	1.0e-121	429	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
651664171	543	63.1	2	541	1	531	0.0e+00	849	COG0504	CTP synthase (UTP-ammonia lyase)	533
651664172	75	45.33	1	73	1	74	2.0e-12	63.7	COG0298	Hydrogenase maturation factor	82
651664175	326	20.51	12	277	1	267	1.0e-11	64.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
651664176	1243	24.24	15	405	13	378	2.0e-25	112	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651664179	332	51.2	49	332	7	279	2.0e-105	376	COG0408	Coproporphyrinogen III oxidase	303
651664180	395	26.4	1	372	2	371	2.0e-38	153	COG1290	Cytochrome b subunit of the bc complex	381
651664181	243	29.83	1	233	1	237	9.0e-33	133	COG2857	Cytochrome c1	250
651664182	297	40.48	6	252	14	262	8.0e-65	240	COG0005	Purine nucleoside phosphorylase	262
651664183	215	38.07	1	191	1	194	1.0e-57	216	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
651664184	269	65.08	18	269	3	253	2.0e-122	431	COG1117	ABC-type phosphate transport system, ATPase component	253
651664185	239	39.74	1	232	2	235	1.0e-44	173	COG0704	Phosphate uptake regulator	240
651664186	236	54.15	9	233	3	229	2.0e-62	232	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
651664188	486	25.15	1	480	2	486	3.0e-43	170	COG0591	Na+/proline symporter	493
651664190	270	37.88	11	268	1	251	3.0e-40	158	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651664191	852	43.2	20	508	1	500	0.0e+00	486	COG1129	ABC-type sugar transport system, ATPase component	500
651664192	355	19.93	13	317	7	306	2.0e-22	99.8	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651664193	300	34.24	1	294	21	315	5.0e-34	138	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
651664194	258	32.85	5	256	73	349	8.0e-38	150	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
651664196	95	32.97	1	89	1	90	1.0e-13	68	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
651664197	356	20.15	8	265	4	260	2.0e-11	63.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
651664200	444	38.33	1	442	9	469	2.0e-103	369	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
651664207	65	52.38	1	63	8	70	2.0e-14	70.3	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
651664208	346	19.62	25	332	2	309	1.0e-05	44.2	COG0582	Integrase	309
651664209	283	24.19	31	277	30	271	2.0e-22	100	COG3176	Putative hemolysin	292
651664214	793	16.4	3	793	6	768	1.0e-18	88.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
651664215	301	34.38	40	295	1	232	2.0e-14	73.5	COG2801	Transposase InsO and inactivated derivatives	232
651664217	383	22.55	13	370	17	362	2.0e-16	80.6	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
651664218	290	32.47	1	228	37	267	8.0e-34	137	COG1216	Glycosyltransferase, GT2 family	305
651664223	149	34.43	1	118	4	125	1.0e-13	69.1	COG1695	DNA-binding transcriptional regulator, PadR family	138
651664225	344	30.77	11	344	4	322	3.0e-39	156	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651664228	83	41.56	3	78	22	91	2.0e-12	64.2	COG2929	Uncharacterized conserved protein, DUF497 family	93
651664229	102	34.12	16	100	12	92	3.0e-11	60.4	COG3514	Uncharacterized conserved protein, DUF4415 family	93
651664230	210	30.65	7	203	5	202	4.0e-14	71.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
651664231	207	25	24	155	4	132	8.0e-11	60.7	COG3415	Transposase	138
651664232	199	40.69	1	199	24	226	9.0e-44	170	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
651664233	321	25.5	25	317	1	295	9.0e-28	117	COG0583	DNA-binding transcriptional regulator, LysR family	297
651664238	356	27.52	120	335	12	216	2.0e-35	143	COG0543	NAD(P)H-flavin reductase	252
651664239	858	29.29	140	514	22	382	2.0e-43	171	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
651664240	467	39.68	228	461	5	248	8.0e-33	135	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651664242	188	23.24	1	172	1	181	4.0e-11	61.1	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
651664243	446	25.56	16	446	10	440	2.0e-54	206	COG2067	Long-chain fatty acid transport protein	440
651664244	541	45.66	1	533	3	537	2.0e-130	459	COG2303	Choline dehydrogenase or related flavoprotein	542
651664245	471	37.47	4	448	27	472	6.0e-91	328	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
651664246	179	22.22	44	169	23	136	2.0e-04	39.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
651664247	572	41.18	35	569	11	524	4.0e-128	451	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
651664248	428	33.72	8	428	2	391	2.0e-56	213	COG0183	Acetyl-CoA acetyltransferase	392
651664251	343	30.99	1	338	7	317	8.0e-39	154	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651664252	262	43.03	12	255	1	244	1.0e-55	210	COG1414	DNA-binding transcriptional regulator, IclR family	246
651664253	646	29.97	18	554	11	598	8.0e-94	338	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
651664254	229	40.48	14	221	7	216	4.0e-28	118	COG1802	DNA-binding transcriptional regulator, GntR family	230
651664255	187	46.5	31	187	39	181	3.0e-32	131	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
651664256	409	51.75	12	409	7	404	0.0e+00	476	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
651664257	311	24.91	12	288	6	297	3.0e-13	69.7	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
651664258	910	55.32	2	903	1	822	0.0e+00	1054	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
651664260	154	42.74	24	146	2	124	1.0e-12	66.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
651664261	163	60.47	35	163	2	130	3.0e-45	174	COG0103	Ribosomal protein S9	130
651664262	178	50.34	22	168	1	147	6.0e-50	190	COG0102	Ribosomal protein L13	148
651664265	614	43.08	166	613	12	445	6.0e-109	388	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
651664266	149	30.97	3	144	2	150	1.0e-17	82.7	COG4539	Uncharacterized membrane protein YGL010W	180
651664267	322	33.33	26	287	7	261	4.0e-19	89.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
651664268	356	39.64	5	328	1	330	4.0e-88	318	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
651664269	319	36.77	7	313	17	304	1.0e-56	213	COG0010	Arginase family enzyme	305
651664270	148	32.89	1	146	3	151	3.0e-21	94.4	COG1522	DNA-binding transcriptional regulator, Lrp family	154
651664272	142	31.45	15	138	1	120	3.0e-10	58.2	COG3293	Transposase	124
651664274	271	23.53	1	271	4	252	9.0e-08	51.2	COG0730	Uncharacterized membrane protein YfcA	258
651664275	277	32.46	162	274	7	120	1.0e-14	74.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
651664276	318	26.07	21	313	19	291	2.0e-14	73.9	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
651664278	321	24.83	12	309	1	296	2.0e-22	99.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
651664285	373	36.36	6	367	2	354	2.0e-72	266	COG3328	Transposase (or an inactivated derivative)	379
651664288	499	31.36	268	487	1	169	6.0e-32	132	COG0516	IMP dehydrogenase/GMP reductase	170
651664289	426	39.14	108	426	29	355	3.0e-70	259	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
651664290	177	24.05	1	153	11	154	2.0e-06	45.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
651664291	313	37.25	20	311	12	300	9.0e-62	230	COG4974	Site-specific recombinase XerD	300
651664292	137	27.07	1	133	2	133	3.0e-20	91	COG0848	Biopolymer transport protein ExbD	137
651664293	223	29	7	201	13	212	3.0e-22	98.9	COG0811	Biopolymer transport protein ExbB/TolQ	216
651664294	607	45.57	1	312	1	314	9.0e-99	354	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
651664295	287	41.27	29	279	27	278	3.0e-49	188	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
651664296	322	43.49	8	322	3	316	1.0e-73	270	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
651664297	551	25.48	1	544	1	554	3.0e-52	199	COG0747	ABC-type transport system, periplasmic component	556
651664299	289	54.74	1	281	2	283	2.0e-103	369	COG2607	Predicted ATPase, AAA+ superfamily	287
651664300	119	34.38	14	109	2	95	6.0e-18	82.9	COG1862	Preprotein translocase subunit YajC	97
651664301	201	49.5	1	200	2	198	5.0e-60	223	COG0605	Superoxide dismutase	204
651664308	258	22.33	8	220	4	210	5.0e-18	84.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
651664309	210	24.41	2	203	3	215	5.0e-10	58	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
651664312	408	45.2	7	399	3	388	4.0e-108	384	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
651664313	310	33.97	25	280	4	257	9.0e-51	194	COG1351	Thymidylate synthase ThyX	273
651664315	209	27.84	1	209	1	255	2.0e-19	89.1	COG1192	Cellulose biosynthesis protein BcsQ	259
651664317	423	47.52	1	419	137	557	4.0e-116	411	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
651664319	108	40	4	64	5	67	4.0e-08	49.8	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
651664322	456	49.56	1	437	4	457	5.0e-126	444	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
651664323	462	28.8	159	458	28	327	4.0e-32	132	COG0642	Signal transduction histidine kinase	336
651664329	142	24.73	20	110	23	111	4.0e-03	33.9	COG3293	Transposase	124
651664332	393	35.19	10	393	139	520	2.0e-83	302	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
651664334	338	30.06	4	325	1	303	2.0e-34	139	COG3547	Transposase	303
651664336	221	21.72	7	204	4	183	6.0e-06	44.6	COG3637	Opacity protein and related surface antigens	199
651664337	860	58.08	5	853	1	782	0.0e+00	972	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
651664338	253	25.47	3	253	2	263	1.0e-23	103	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
651664339	194	41.97	1	191	10	192	5.0e-20	90.8	COG0558	Phosphatidylglycerophosphate synthase	192
651664340	179	42.94	13	172	2	161	4.0e-35	141	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
651664342	83	33.73	1	83	2	84	9.0e-16	75.4	COG1977	Molybdopterin converting factor, small subunit	84
651664343	147	45.95	1	146	3	149	2.0e-36	144	COG0314	Molybdopterin synthase catalytic subunit	149
651664346	583	38.51	8	573	23	594	0.0e+00	495	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
651664347	677	54.12	24	677	3	662	0.0e+00	884	COG0021	Transketolase	663
651664348	337	59.76	2	336	1	332	5.0e-123	434	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
651664349	397	47.63	1	397	1	393	1.0e-129	456	COG0126	3-phosphoglycerate kinase	395
651664350	483	39.73	39	481	17	454	2.0e-106	380	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
651664351	358	29.36	10	351	4	322	2.0e-25	110	COG1612	Heme A synthase	323
651664352	367	30.84	24	367	1	319	2.0e-34	140	COG1612	Heme A synthase	323
651664353	424	71.7	1	424	4	420	0.0e+00	696	COG1158	Transcription termination factor Rho	422
651664359	119	23.2	4	119	12	136	4.0e-12	63.5	COG4190	Predicted transcriptional regulator	144
651664364	536	39.38	76	521	7	454	2.0e-109	389	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
651664365	137	33.63	3	114	2	114	2.0e-18	84.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
651664368	812	40.94	2	404	5	361	3.0e-90	327	COG4951	Uncharacterized protein	361
651664374	240	31.48	10	223	5	215	2.0e-21	96.5	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
651664375	661	34.86	6	178	27	201	8.0e-25	109	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
651664376	225	48.26	1	224	1	229	6.0e-60	224	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
651664377	447	36.54	142	440	34	325	7.0e-41	161	COG0642	Signal transduction histidine kinase	336
651664378	423	22.25	37	414	45	442	4.0e-14	72.9	COG1538	Outer membrane protein TolC	457
651664380	1033	31.43	1	1028	1	1025	0.0e+00	611	COG3696	Cu/Ag efflux pump CusA	1027
651664384	221	37.61	116	220	1	107	3.0e-12	65.3	COG0607	Rhodanese-related sulfurtransferase	110
651664385	243	28.76	15	213	26	252	9.0e-13	67.6	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
651664386	416	21.45	40	405	50	430	2.0e-09	57.1	COG2271	Sugar phosphate permease	448
651664387	247	34.92	2	247	55	345	1.0e-37	149	COG1566	Multidrug resistance efflux pump	352
651664389	249	28.98	7	246	7	230	3.0e-32	132	COG2243	Precorrin-2 methylase	234
651664390	242	45.3	1	234	2	231	5.0e-54	204	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
651664391	445	48.51	13	441	1	435	0.0e+00	469	COG1797	Cobyrinic acid a,c-diamide synthase	451
651664392	210	55.78	2	198	55	252	1.0e-70	259	COG2875	Precorrin-4 methylase	254
651664394	196	44.32	16	196	3	186	2.0e-43	169	COG2242	Precorrin-6B methylase 2	187
651664396	196	32.98	13	196	13	199	9.0e-29	120	COG1484	DNA replication protein DnaC	254
651664398	342	33.94	5	328	1	303	1.0e-35	144	COG3547	Transposase	303
651664400	191	32.09	3	187	8	192	6.0e-22	97.6	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
651664401	296	32.24	3	240	30	274	2.0e-26	113	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
651664402	408	41.04	6	394	4	405	8.0e-79	287	COG2223	Nitrate/nitrite transporter NarK	417
651664403	814	56.98	6	807	1	789	0.0e+00	1055	COG1251	NAD(P)H-nitrite reductase, large subunit	793
651664404	116	34.29	7	110	2	106	1.0e-19	88.5	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
651664405	861	31.29	3	670	43	764	5.0e-121	429	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
651664406	261	51.03	12	254	5	244	4.0e-63	234	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
651664407	194	27.78	1	175	3	177	1.0e-10	60.3	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
651664413	396	37.31	1	385	2	382	7.0e-98	351	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
651664416	375	23.36	67	338	20	260	8.0e-11	61.8	COG4974	Site-specific recombinase XerD	300
651664417	346	26.27	77	308	6	233	6.0e-17	81.9	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
651664418	397	29.35	113	386	3	258	5.0e-42	165	COG1192	Cellulose biosynthesis protein BcsQ	259
651664423	99	32.98	1	94	2	95	2.0e-13	67.6	COG4453	Uncharacterized conserved protein, DUF1778 family	95
651664425	80	38.27	1	79	1	81	3.0e-07	46.8	COG4423	Uncharacterized protein	81
651664426	136	43.18	2	132	1	129	1.0e-28	118	COG3742	Uncharacterized protein, contains PIN domain	131
651664427	353	39.55	4	309	11	309	3.0e-68	252	COG4227	Antirestriction protein ArdC	316
651664428	96	36.96	1	90	2	91	1.0e-09	54.7	COG3668	Plasmid stabilization system protein ParE	98
651664430	181	40	1	178	2	196	3.0e-25	108	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
651664431	542	38.05	1	542	26	566	7.0e-115	408	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
651664433	368	27.96	72	367	93	379	8.0e-26	111	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651664434	355	27.96	67	338	103	380	3.0e-30	126	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651664436	408	17.75	37	354	28	360	5.0e-03	35.9	COG3307	O-antigen ligase	424
651664437	217	25.1	1	198	2	248	3.0e-22	98.7	COG1192	Cellulose biosynthesis protein BcsQ	259
651664443	92	31.91	1	92	2	93	7.0e-08	48.9	COG3668	Plasmid stabilization system protein ParE	98
651664446	292	49.8	28	275	1	251	6.0e-74	271	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
651664452	274	25.93	31	273	18	245	1.0e-22	100	COG3547	Transposase	303
651664454	253	35.83	11	248	2	228	8.0e-50	190	COG2063	Flagellar basal body L-ring protein FlgH	230
651664456	260	49.24	1	260	2	263	1.0e-70	260	COG4786	Flagellar basal body rod protein FlgG	265
651664457	247	31.82	1	241	1	264	2.0e-40	159	COG4786	Flagellar basal body rod protein FlgG	265
651664465	128	48.36	2	122	3	124	8.0e-27	112	COG3744	PIN domain nuclease, a component of toxin-antitoxin system (PIN domain)	130
651664466	81	26.58	1	79	2	78	2.0e-06	43.9	COG4118	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor	84
651664470	113	39.56	6	92	4	91	9.0e-15	72.2	COG2929	Uncharacterized conserved protein, DUF497 family	93
651664473	346	31.52	4	329	1	303	3.0e-28	119	COG3547	Transposase	303
651664474	227	22.14	1	222	2	258	5.0e-15	74.8	COG1192	Cellulose biosynthesis protein BcsQ	259
651664480	292	45.31	165	292	2	128	3.0e-29	122	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
651664482	359	28.11	119	335	8	223	9.0e-22	97.9	COG1802	DNA-binding transcriptional regulator, GntR family	230
651664486	195	23.71	89	185	1	93	1.0e-04	40.1	COG3293	Transposase	124
651664487	199	42.64	10	190	4	200	3.0e-32	131	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
651664488	116	29.91	2	116	32	148	7.0e-12	62.6	COG1981	Uncharacterized membrane protein	149
651664489	124	53.91	5	118	3	117	2.0e-33	134	COG3189	Uncharacterized conserved protein YeaO, DUF488 family	117
651664490	115	38.46	22	111	32	122	6.0e-13	66.2	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
651664492	555	25.45	19	491	17	486	1.0e-51	198	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
651664493	211	34.18	8	162	3	157	6.0e-21	94.3	COG4185	Predicted ABC-type ATPase	187
651664496	220	29.08	1	203	2	251	2.0e-23	102	COG1192	Cellulose biosynthesis protein BcsQ	259
651664497	375	24.1	67	338	20	260	3.0e-10	59.8	COG4974	Site-specific recombinase XerD	300
651664500	410	29.56	5	408	27	382	2.0e-40	160	COG1680	CubicO group peptidase, beta-lactamase class C family	390
651664501	230	30.04	1	218	19	239	3.0e-43	168	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
651664502	67	30.88	1	66	3	70	2.0e-03	34.6	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
651664507	299	30.3	1	294	1	295	2.0e-28	119	COG0583	DNA-binding transcriptional regulator, LysR family	297
651664508	292	28.11	1	273	1	275	3.0e-23	102	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
651664509	315	37.75	12	303	15	311	5.0e-40	158	COG0657	Acetyl esterase/lipase	312
651664512	321	26.03	79	315	35	254	1.0e-17	83.8	COG0725	ABC-type molybdate transport system, periplasmic component	258
651664514	289	36.9	10	288	3	292	1.0e-63	236	COG3258	Cytochrome c	293
651664515	178	31.91	85	178	27	117	2.0e-12	65.8	COG2863	Cytochrome c553	121
651664518	403	46.85	1	394	1	388	4.0e-120	425	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
651664519	606	30.97	259	600	3	320	5.0e-51	196	COG0523	GTPase, G3E family	323
651664523	314	42.32	6	272	63	323	1.0e-62	233	COG4644	Transposase and inactivated derivatives, TnpA family	323
651664525	119	28.93	8	119	16	136	7.0e-13	66.2	COG4190	Predicted transcriptional regulator	144
651664530	248	21.43	24	248	1	229	5.0e-19	88.3	COG1794	Aspartate/glutamate racemase	230
651664532	231	33.04	7	224	4	226	1.0e-27	116	COG1011	FMN phosphatase YigB, HAD superfamily	229
651664533	173	21.43	12	156	11	155	9.0e-06	43.3	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
651664534	191	30.4	59	180	53	177	4.0e-13	68.3	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
651664535	234	24.89	20	232	9	207	7.0e-14	71	COG0625	Glutathione S-transferase	211
651664536	239	34.13	5	205	1	201	2.0e-36	145	COG0625	Glutathione S-transferase	211
651664537	201	20	1	189	6	189	2.0e-06	46.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
651664538	223	33.94	6	217	4	212	2.0e-40	159	COG3531	Predicted protein-disulfide isomerase , contains CxxC motif	212
651664539	414	19.79	25	408	19	382	4.0e-09	56.4	COG2814	Predicted arabinose efflux permease, MFS family	394
651664540	243	28.33	15	213	26	252	4.0e-13	68.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
651664541	221	37.61	116	220	1	107	5.0e-13	68	COG0607	Rhodanese-related sulfurtransferase	110
651664542	90	32.47	9	85	3	74	2.0e-05	40.7	COG4456	Virulence-associated protein VagC (function unknown)	74
651664543	313	39.29	14	191	2	196	5.0e-25	108	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
651664546	782	32.99	2	780	22	794	0.0e+00	548	COG3451	Type IV secretory pathway, VirB4 component	796
651664547	107	40	4	97	8	100	1.0e-13	68	COG3702	Type IV secretory pathway, VirB3 components	105
651664551	199	40.89	1	198	24	225	1.0e-42	166	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
651664557	355	28.9	17	320	8	289	9.0e-58	217	COG0630	Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase	312
651664558	607	23.67	117	601	98	563	3.0e-65	243	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
651664560	418	26.59	2	352	1	350	9.0e-46	177	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
651664562	227	45.54	1	221	1	222	3.0e-53	201	COG2135	Putative SOS response-associated peptidase YedK	226
651664569	296	28.16	17	293	19	264	7.0e-31	128	COG3504	Type IV secretory pathway, VirB9 components	265
651664581	245	26.38	44	243	3	251	4.0e-21	95.3	COG1192	Cellulose biosynthesis protein BcsQ	259
651664586	706	35.82	8	695	11	685	1.0e-112	401	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
651664589	247	45.95	12	230	1	220	2.0e-53	202	COG2135	Putative SOS response-associated peptidase YedK	226
651664591	418	27.15	2	352	1	350	6.0e-45	175	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
651664593	606	24.29	116	600	98	563	2.0e-65	244	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
651664594	355	28.9	17	320	8	289	6.0e-58	218	COG0630	Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase	312
651664599	199	46.97	1	195	1	189	4.0e-50	190	COG2156	K+-transporting ATPase, c chain	190
651664605	706	37.89	1	706	158	880	0.0e+00	519	COG2205	K+-sensing histidine kinase KdpD	890
651664607	782	32.74	2	780	22	794	0.0e+00	544	COG3451	Type IV secretory pathway, VirB4 component	796
651664608	107	40	4	97	8	100	1.0e-13	68.4	COG3702	Type IV secretory pathway, VirB3 components	105
651664611	93	62.22	1	90	1	90	2.0e-24	103	COG5606	Predicted DNA-binding protein, XRE-type HTH domain	91
651664612	219	28.05	1	199	2	246	2.0e-21	96.4	COG1192	Cellulose biosynthesis protein BcsQ	259
651664615	80	38.27	1	79	1	81	3.0e-07	46.8	COG4423	Uncharacterized protein	81
651664616	136	43.94	2	132	1	129	2.0e-29	121	COG3742	Uncharacterized protein, contains PIN domain	131
651664617	330	34.2	8	301	7	291	1.0e-44	173	COG4974	Site-specific recombinase XerD	300
651664620	269	43.55	9	254	7	254	3.0e-58	219	COG1484	DNA replication protein DnaC	254
651664621	261	28.87	25	253	31	253	2.0e-19	89.9	COG4974	Site-specific recombinase XerD	300
651664622	424	32.12	127	413	6	292	2.0e-32	133	COG4974	Site-specific recombinase XerD	300
651664624	324	38.78	14	191	2	196	8.0e-26	111	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
651664630	238	36.52	7	232	2	219	8.0e-37	147	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
651664631	400	26.73	2	398	25	416	1.0e-30	128	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
651664632	150	41.03	31	146	5	121	7.0e-24	103	COG1321	Mn-dependent transcriptional regulator, DtxR family	154
651664634	387	25.83	1	385	38	415	2.0e-29	123	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
651664635	303	30.83	177	295	1	120	1.0e-17	84.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
651664637	87	34.52	3	86	2	81	8.0e-06	42.2	COG2336	Antitoxin component of the MazEF toxin-antitoxin module	82
651664638	219	23.11	1	201	3	240	1.0e-18	86.4	COG1192	Cellulose biosynthesis protein BcsQ	259
651664640	392	24.15	88	388	2	313	1.0e-13	71.3	COG5534	Plasmid replication initiator protein	383
651664642	145	26.9	1	140	3	133	3.0e-11	61.3	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
651664644	881	23.08	5	696	31	683	6.0e-70	259	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
651664651	65	38	6	55	5	53	1.0e-05	41.4	COG5428	Uncharacterized protein YuzE	69
