gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
2919587334	684	94.62	293	648	4	302	2.5e-58	190.5	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2919587335	298	55.21	4	296	11	275	5.4e-80	264	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2919587337	675	47.84	549	673	2	112	2.4e-29	62.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919587337	675	48.71	414	528	2	114	2.4e-29	31.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919587337	675	82.74	5	404	68	393	5.2e-77	254.5	COG0642	Signal transduction histidine kinase	336
2919587340	275	99.25	2	272	2	264	1.8e-95	313.3	COG0159	Tryptophan synthase alpha chain	265
2919587341	307	96.94	6	296	3	287	3.3e-117	385.1	COG0777	Acetyl-CoA carboxylase beta subunit	294
2919587342	441	97.2	1	441	7	423	3.2e-119	393.1	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
2919587343	297	99.58	1	294	2	236	1.9e-20	67	COG3637	Opacity protein and related surface antigens	199
2919587344	107	33.44	1	106	27	128	3.3e-38	126.4	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2919587345	429	92.49	3	427	31	412	9.9e-112	368.2	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2919587346	1160	14.58	972	1139	981	1148	0.0e+00	38.6	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2919587346	1160	73.35	4	902	5	849	0.0e+00	561.6	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2919587347	1043	98.88	765	1042	1	266	1.2e-40	133	COG2887	RecB family exonuclease	269
2919587347	1043	99	4	749	2	692	0.0e+00	532	COG3893	Inactivated superfamily I helicase	697
2919587348	249	62.17	11	249	4	238	4.5e-44	145.2	COG1208	NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins	358
2919587349	533	80.54	26	170	3	122	2.4e-33	109	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
2919587349	533	96.58	182	526	3	341	5.5e-108	355.2	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
2919587350	207	41.3	11	207	72	211	6.3e-10	33.3	COG4254	Uncharacterized conserved protein, contains LysM and FecR  domains	339
2919587351	419	96.5	147	408	4	251	1.4e-81	267.3	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2919587352	719	93.03	419	671	11	237	3.0e-49	160.9	COG2114	Adenylate cyclase, class 3	227
2919587355	49	23.18	1	35	117	151	1.7e-07	25.7	COG1513	Cyanate lyase	151
2919587357	133	95.83	1	133	4	141	1.2e-29	96.8	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2919587359	737	39.62	168	361	4	127	4.0e-38	53.5	COG1216	Glycosyltransferase, GT2 family	305
2919587359	737	71.88	422	664	7	231	4.0e-38	68.1	COG1216	Glycosyltransferase, GT2 family	305
2919587360	463	98.56	4	461	5	416	3.1e-90	297.7	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2919587361	172	96.79	14	171	2	152	1.2e-68	224.1	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2919587362	337	98.95	1	327	1	283	1.4e-97	321.1	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2919587363	745	98.79	4	745	5	740	0.0e+00	634.7	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919587364	298	68.74	1	290	135	433	4.0e-65	214.5	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2919587368	273	59.66	2	253	159	402	2.9e-43	142.4	COG0672	High-affinity Fe2+/Pb2+ permease	383
2919587372	145	97.86	5	144	2	138	1.5e-50	165.3	COG2510	Uncharacterized membrane protein	140
2919587373	122	96.83	1	122	4	125	2.4e-32	106	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
2919587374	227	97.16	5	202	5	209	5.5e-25	82.5	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919587375	471	96.93	2	455	2	443	0.0e+00	549.8	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
2919587376	119	88.64	1	119	11	127	2.7e-41	134.8	COG2343	Uncharacterized conserved protein, DUF427 family	132
2919587377	302	61.29	4	270	54	224	2.5e-10	35.3	COG0500	SAM-dependent methyltransferase	257
2919587378	76	22.35	3	70	71	110	1.3e-03	13.1	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
2919587380	55	17.86	2	50	182	221	1.1e-14	48.8	COG1040	Predicted amidophosphoribosyltransferases	225
2919587384	137	17.18	7	126	325	402	3.0e+00	.7	COG3846	Type IV secretory pathway, TrbL components	452
2919587385	492	98.77	4	490	6	485	0.0e+00	634.5	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
2919587386	126	73.61	10	119	18	123	3.4e-04	14.5	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2919587387	281	87.69	7	258	5	239	1.7e-36	120.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919587388	379	89.52	7	368	32	347	2.1e-61	202.2	COG3693	Endo-1,4-beta-xylanase, GH35 family	345
2919587389	526	62.61	74	464	200	559	1.9e-112	371.2	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
2919587390	176	94.27	14	169	6	153	3.9e-42	138.2	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
2919587391	889	11.51	632	718	191	263	0.0e+00	9.1	COG1042	Acyl-CoA synthetase (NDP forming)	598
2919587391	889	80.75	718	880	5	155	5.0e-14	46.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2919587391	889	99.21	4	628	5	633	0.0e+00	511.9	COG1042	Acyl-CoA synthetase (NDP forming)	598
2919587392	236	92.86	6	218	7	214	6.3e-53	173.9	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2919587394	166	89.86	2	147	12	144	2.9e-67	219.4	COG4957	Predicted transcriptional regulator	148
2919587396	506	98.77	14	501	4	483	0.0e+00	547.2	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
2919587397	498	98.04	13	478	1	451	2.2e-107	354	COG1538	Outer membrane protein TolC	457
2919587398	1112	24.06	837	1092	770	1013	0.0e+00	284.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2919587398	1112	76.73	2	840	2	779	0.0e+00	843.1	COG0841	Multidrug efflux pump subunit AcrB	1009
2919587399	1050	99.7	11	1031	3	1013	0.0e+00	1132.8	COG0841	Multidrug efflux pump subunit AcrB	1009
2919587400	450	96.41	20	413	10	385	2.0e-64	212.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919587401	393	97.73	11	393	7	393	4.6e-100	329.7	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2919587403	393	98.83	30	392	4	340	0.0e+00	544.3	COG4239	ABC-type microcin C transport system, permease component YejE	341
2919587405	593	97.01	24	562	7	557	1.8e-77	255.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919587406	357	8.79	284	321	264	290	1.8e-38	2	COG1897	Homoserine trans-succinylase	307
2919587406	357	73.29	26	283	36	260	1.8e-38	123.1	COG1897	Homoserine trans-succinylase	307
2919587407	430	98.13	1	423	8	426	0.0e+00	597.9	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
2919587408	151	84.48	3	116	18	115	2.7e-28	92.5	COG3450	Predicted enzyme of the cupin superfamily	116
2919587409	286	98.6	8	286	3	283	4.2e-57	188.5	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2919587410	557	98.38	5	554	2	547	0.0e+00	546.8	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2919587411	545	97.06	1	539	10	570	2.6e-112	371	COG0747	ABC-type transport system, periplasmic component	556
2919587412	762	89.09	217	753	40	390	5.8e-42	139.3	COG0642	Signal transduction histidine kinase	336
2919587416	486	99.15	7	470	2	466	4.0e-100	330.1	COG0277	FAD/FMN-containing dehydrogenase	459
2919587417	117	52.08	27	116	57	131	9.1e-15	48.8	COG4190	Predicted transcriptional regulator	144
2919587421	116	75.35	1	100	6	112	1.5e-12	41.9	COG3692	Uncharacterized protein YifN, PemK superfamily	142
2919587422	265	99.25	1	265	3	267	3.7e-95	312.8	COG0289	Dihydrodipicolinate reductase	266
2919587423	211	98.26	2	206	3	228	7.4e-79	254.4	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
2919587424	236	90.86	60	232	11	179	1.6e-48	158.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919587426	223	89	2	195	13	190	7.7e-51	167.2	COG3145	Alkylated DNA repair dioxygenase AlkB	194
2919587428	477	99.57	22	472	2	468	7.1e-120	395.3	COG0277	FAD/FMN-containing dehydrogenase	459
2919587429	121	86.03	2	121	15	131	1.5e-42	139.2	COG3474	Cytochrome c2	135
2919587430	151	87.22	11	146	3	118	7.6e-28	91.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919587431	140	97.2	1	140	4	142	1.8e-47	155.5	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2919587432	272	70.25	3	260	29	224	9.4e-17	56.1	COG0500	SAM-dependent methyltransferase	257
2919587433	330	97	21	320	9	299	2.6e-98	323.2	COG4974	Site-specific recombinase XerD	300
2919587435	200	97.09	20	191	3	169	1.1e-55	182.7	COG0703	Shikimate kinase	172
2919587436	384	98.61	16	383	4	358	4.3e-123	405.4	COG0337	3-dehydroquinate synthetase	360
2919587438	436	98.11	6	428	3	417	0.0e+00	503.3	COG4536	Mg2+ and Co2+ transporter CorB, contains DUF21, CBS pair, and CorC-HlyC domains	423
2919587439	384	96.17	201	378	7	182	1.8e-46	152.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919587440	644	97.61	14	644	16	627	0.0e+00	738.2	COG3158	K+ transporter	627
2919587441	225	88.79	1	221	2	199	6.5e-43	141.3	COG0132	Dethiobiotin synthetase	223
2919587442	257	98.88	1	254	4	268	1.5e-62	205.8	COG1018	Ferredoxin-NADP reductase	266
2919587443	310	87.67	4	148	2	129	5.9e-36	100.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919587443	310	99.32	151	272	2	146	5.9e-36	21.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919587444	427	96.11	1	426	9	428	3.8e-80	264	COG0612	Predicted Zn-dependent peptidase	438
2919587445	472	94.51	38	464	17	429	1.1e-99	328.1	COG0612	Predicted Zn-dependent peptidase	438
2919587447	175	92.22	3	172	9	162	6.1e-38	124.2	COG0597	Lipoprotein signal peptidase	167
2919587448	991	99.68	11	982	2	945	0.0e+00	1005.5	COG0060	Isoleucyl-tRNA synthetase	933
2919587450	315	96.01	24	312	9	297	7.8e-41	134.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919587451	224	93.98	60	191	5	129	5.4e-24	78.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919587452	129	88.72	9	128	6	123	7.5e-14	46	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919587453	417	97.09	1	417	10	443	0.0e+00	475.9	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2919587456	379	98.72	6	375	4	388	9.1e-122	400.5	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
2919587457	1137	71.65	397	618	32	218	2.1e-31	102.6	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2919587457	1137	94.37	631	1134	17	552	5.5e-77	253.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919587458	203	79.43	5	202	19	184	1.2e-10	36.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919587460	96	70.77	1	93	38	129	7.5e-21	68.8	COG3744	PIN domain nuclease, a component of toxin-antitoxin system (PIN domain)	130
2919587462	339	83.62	4	167	7	154	1.0e-69	107.4	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2919587462	339	90.96	168	338	10	170	1.0e-69	119.5	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2919587463	154	95.3	1	151	4	145	7.2e-50	163.1	COG0314	Molybdopterin synthase catalytic subunit	149
2919587464	371	81.07	9	310	9	282	7.4e-31	101.4	COG4093	Uncharacterized protein	338
2919587466	262	79.31	9	246	26	232	5.7e-44	144.6	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2919587467	579	97.61	20	578	12	543	0.0e+00	654.7	COG0405	Gamma-glutamyltranspeptidase	539
2919587470	242	98.71	6	241	2	230	2.3e-73	240.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919587471	581	71.57	232	580	109	390	1.1e-56	187.6	COG0642	Signal transduction histidine kinase	336
2919587471	581	91.73	23	163	8	129	1.5e-07	24.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919587472	238	92.22	1	235	12	248	2.2e-67	221.1	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
2919587476	780	94.9	55	780	30	736	0.0e+00	443.9	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919587477	161	96.15	1	152	4	153	1.4e-63	207.6	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2919587478	674	97.93	53	674	14	627	0.0e+00	861.2	COG3158	K+ transporter	627
2919587479	436	98.38	24	433	2	365	2.2e-130	429.3	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
2919587480	386	71.79	39	385	8	236	9.2e-52	170.6	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2919587481	208	86.02	6	168	23	182	3.9e-38	125.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919587482	257	98.44	1	253	3	255	1.1e-21	72.2	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2919587483	331	97.39	13	319	8	306	3.1e-93	306.5	COG0196	FAD synthase	304
2919587484	127	89.47	4	127	6	124	1.6e-28	93.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919587485	177	15.67	4	87	45	78	1.3e-10	8.1	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2919587485	177	37.79	79	177	130	211	1.3e-10	26.4	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2919587486	307	89.26	23	296	3	243	1.4e-54	179.5	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
2919587487	487	92.22	207	462	7	243	4.5e-22	69.7	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2919587488	74	89.04	9	72	6	70	3.9e-12	40.7	COG2608	Copper chaperone CopZ	71
2919587489	449	96.64	15	448	9	440	0.0e+00	479.1	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2919587490	557	100	3	557	1	554	0.0e+00	874.7	COG2759	Formyltetrahydrofolate synthetase	554
2919587491	97	55.95	2	90	3	49	3.8e-04	15	COG4118	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor	84
2919587493	121	50	2	120	2	117	8.2e-26	85	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919587494	189	95.53	1	180	7	177	3.1e-62	203.6	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
2919587496	232	97.31	14	232	1	217	3.4e-85	279.7	COG2884	ABC-type ATPase involved in cell division	223
2919587497	316	95.96	15	316	10	294	2.8e-53	175.2	COG2177	Cell division protein FtsX	297
2919587498	264	84.85	32	237	25	220	6.6e-23	75.6	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
2919587500	143	89.47	1	140	15	150	9.2e-37	120.5	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
2919587501	205	90	2	117	3	101	5.3e-20	65.8	COG1544	Ribosome-associated translation inhibitor RaiA	110
2919587502	521	99.11	3	515	3	446	0.0e+00	515.6	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
2919587503	299	98.77	60	299	4	243	1.4e-113	372.3	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
2919587504	242	93.06	23	211	10	170	1.5e-33	109.4	COG1934	Lipopolysaccharide export system protein LptA	173
2919587505	243	95.83	6	220	6	212	1.6e-43	142.9	COG5375	Uncharacterized protein	216
2919587506	208	53.31	12	208	13	205	6.7e-73	240.2	COG0349	Ribonuclease D	361
2919587507	130	46.84	6	127	83	156	3.4e-16	54.3	COG1555	DNA uptake protein ComE and related DNA-binding proteins	149
2919587508	62	98.25	1	57	1	56	9.7e-28	90.6	COG0333	Ribosomal protein L32	57
2919587510	199	98.45	1	196	3	192	1.5e-73	241.5	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
2919587511	394	99.49	4	394	2	393	0.0e+00	509.4	COG0183	Acetyl-CoA acetyltransferase	392
2919587512	242	98.88	1	241	3	267	4.9e-71	233.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919587514	146	90.24	1	146	5	152	6.1e-51	167.1	COG3542	Predicted sugar epimerase, cupin superfamily	162
2919587515	584	78.57	1	190	14	167	1.5e-13	45.6	COG4961	Flp pilus assembly protein TadG	185
2919587519	144	96.45	10	144	5	140	8.8e-37	120.9	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
2919587520	328	96.35	5	299	8	297	1.1e-77	255.6	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2919587521	412	78.35	272	412	22	173	8.5e-05	10.6	COG1525	Endonuclease YncB, thermonuclease family	192
2919587522	272	30.88	6	202	68	201	7.6e-03	9.5	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2919587523	311	97.35	7	298	4	297	5.9e-73	239.7	COG1597	Diacylglycerol kinase family enzyme	301
2919587524	261	96.09	1	246	6	251	2.8e-83	273.3	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2919587525	731	96.48	1	729	10	776	4.2e-93	307.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2919587526	282	34.91	45	254	128	208	1.6e-18	61.8	COG0671	Membrane-associated phospholipid phosphatase	232
2919587527	290	45.76	9	288	39	173	1.0e-07	26.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919587528	280	98.53	3	280	3	270	5.3e-96	315.7	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
2919587529	150	61.93	9	149	5	139	7.1e-15	48.8	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919587530	228	97.84	5	228	2	228	1.5e-63	208.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919587531	178	77.88	1	178	47	215	1.6e-56	185.9	COG3786	L,D-peptidoglycan transpeptidase YkuD, ErfK/YbiS/YcfS/YnhG family	217
2919587532	430	89.87	15	420	34	388	1.4e-18	60.6	COG2814	Predicted arabinose efflux permease, MFS family	394
2919587533	149	94.74	17	140	2	127	2.8e-17	57.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919587534	264	98.25	43	263	3	227	4.7e-72	236.7	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
2919587535	868	99.76	10	868	3	823	0.0e+00	1010.9	COG0495	Leucyl-tRNA synthetase	814
2919587536	186	97.67	13	185	4	171	1.7e-28	94	COG5468	Predicted secreted (periplasmic) protein	172
2919587537	342	90.12	6	335	15	315	4.9e-54	178	COG1466	DNA polymerase III, delta subunit	334
2919587538	285	61.4	18	229	39	178	4.4e-35	115.5	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2919587539	297	97.73	32	288	6	263	1.9e-69	228.8	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2919587540	280	96.97	16	276	3	258	1.1e-78	259	COG1192	Cellulose biosynthesis protein BcsQ	259
2919587541	210	86.51	1	207	11	196	1.4e-44	146.5	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
2919587542	626	98.72	5	623	4	619	0.0e+00	840	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
2919587543	433	99.34	1	433	4	454	3.5e-121	399.4	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
2919587544	447	99.05	27	447	2	419	0.0e+00	718.4	COG1158	Transcription termination factor Rho	422
2919587545	214	94.57	5	214	8	181	1.8e-34	111.4	COG2840	DNA-nicking endonuclease, Smr domain	184
2919587546	401	76.78	37	401	86	376	5.3e-82	270.4	COG2821	Membrane-bound lytic murein transglycosylase	373
2919587547	241	82.21	4	240	49	279	1.2e-54	180.3	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
2919587548	169	92.36	12	166	6	150	2.8e-53	174	COG1952	Preprotein translocase subunit SecB	157
2919587549	410	49.87	205	407	5	195	2.6e-23	46.2	COG0477	MFS family permease	338
2919587549	410	69.97	1	242	9	276	2.6e-23	35	COG0477	MFS family permease	338
2919587551	517	98.15	15	509	4	427	5.8e-117	385.1	COG0124	Histidyl-tRNA synthetase	429
2919587552	394	92.84	12	383	20	382	9.8e-60	190.8	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
2919587553	327	96.93	6	314	3	286	8.9e-62	203.3	COG0040	ATP phosphoribosyltransferase	290
2919587554	132	23.08	19	89	43	63	3.5e-04	15	COG5606	Predicted DNA-binding protein, XRE-type HTH domain	91
2919587555	128	95	1	121	3	116	6.2e-33	107.6	COG4683	Uncharacterized protein	120
2919587556	114	52.43	1	112	7	103	6.1e-27	88.7	COG4461	Uncharacterized protein YPO0702	185
2919587557	143	95.97	1	142	6	148	6.9e-55	179.9	COG1981	Uncharacterized membrane protein	149
2919587558	386	35.41	249	385	220	344	3.3e-95	80.9	COG0407	Uroporphyrinogen-III decarboxylase	352
2919587558	386	59.49	1	234	8	217	3.3e-95	230.9	COG0407	Uroporphyrinogen-III decarboxylase	352
2919587559	276	98.53	3	273	2	270	2.7e-99	326.5	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
2919587561	207	95.88	11	206	4	189	7.6e-50	163.1	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
2919587562	344	99	33	333	2	297	4.5e-88	289.8	COG1230	Co/Zn/Cd efflux system component	296
2919587563	279	95.77	1	276	7	278	2.5e-88	290.1	COG0169	Shikimate 5-dehydrogenase	283
2919587564	208	96.52	9	207	3	196	5.0e-56	184	COG0237	Dephospho-CoA kinase	201
2919587565	78	54.55	15	73	26	61	1.8e-04	15.8	COG1724	Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family	66
2919587566	75	82.19	4	73	4	63	1.8e-18	60.5	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
2919587567	241	68.11	1	221	18	190	1.5e-56	186.6	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2919587568	148	86.52	23	105	2	78	4.1e-10	34.2	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
2919587569	437	87.22	147	435	39	311	2.4e-54	178.6	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2919587570	288	97.54	11	288	5	282	1.3e-106	350.1	COG0414	Panthothenate synthetase	285
2919587572	158	94.84	4	157	2	148	2.5e-48	158	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
2919587573	299	89.52	5	299	27	325	1.8e-61	202.6	COG2367	Beta-lactamase class A	329
2919587577	336	63.5	46	296	89	262	6.0e-10	32.9	COG1240	Mg-chelatase subunit ChlD	261
2919587579	307	54.92	28	298	165	393	7.3e-29	95.3	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2919587580	336	96.67	14	336	9	327	2.1e-88	290.9	COG0714	MoxR-like ATPase	329
2919587581	238	96.46	9	234	8	225	9.9e-56	183.2	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
2919587582	228	78.73	1	221	3	213	4.6e-33	109.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919587585	152	95.95	10	150	4	145	9.3e-25	81.8	COG0394	Protein-tyrosine-phosphatase	139
2919587586	164	98.12	5	164	4	160	1.3e-71	234.2	COG5328	Uncharacterized protein, UPF0262 family	160
2919587587	431	98.83	1	431	3	426	0.0e+00	584.3	COG0141	Histidinol dehydrogenase	425
2919587589	429	99.52	1	429	1	419	0.0e+00	583.1	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
2919587591	428	99.49	18	411	2	389	0.0e+00	467	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
2919587592	244	32.34	1	106	2	99	2.6e-35	67.6	COG1234	Ribonuclease BN, tRNA processing enzyme	292
2919587592	244	38.28	102	244	157	272	2.6e-35	47.2	COG1234	Ribonuclease BN, tRNA processing enzyme	292
2919587594	178	73.94	11	166	8	112	2.4e-06	19.8	COG3431	Uncharacterized membrane protein, DUF373 family	142
2919587595	203	95.6	2	188	3	176	7.9e-22	72.1	COG5436	Uncharacterized membrane protein	182
2919587596	229	96.91	35	229	6	193	1.1e-48	160	COG5402	Uncharacterized protein	194
2919587597	763	90.46	50	735	21	665	0.0e+00	629.4	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2919587598	167	91.5	4	157	5	144	2.7e-60	197	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
2919587599	167	95.21	6	167	3	161	2.7e-66	217	COG3685	Ferritin-like metal-binding protein YciE	167
2919587600	260	96.39	4	259	8	247	9.1e-62	203	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
2919587601	127	82.09	1	64	5	59	6.1e-13	42.2	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2919587602	70	92.54	1	67	1	62	2.0e-22	73.4	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2919587603	336	98.38	1	327	1	304	3.0e-74	243.4	COG1893	Ketopantoate reductase	307
2919587604	228	60.93	1	221	18	187	2.7e-10	35.4	COG0500	SAM-dependent methyltransferase	257
2919587605	403	95.43	21	397	15	369	0.0e+00	494	COG2021	Homoserine acetyltransferase	368
2919587606	288	78.22	7	100	9	87	4.1e-11	36.5	COG1605	Chorismate mutase	101
2919587607	377	98.34	15	374	3	357	7.2e-105	345	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2919587608	318	98.57	9	293	4	278	3.1e-88	290	COG0287	Prephenate dehydrogenase	279
2919587609	423	27.22	13	166	16	113	8.2e-57	27.9	COG0628	Predicted PurR-regulated permease PerM	355
2919587609	423	59.44	186	423	138	351	8.2e-57	158.2	COG0628	Predicted PurR-regulated permease PerM	355
2919587610	412	96.88	1	411	8	473	2.8e-75	248.3	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2919587613	222	86	2	222	33	247	5.0e-51	167.9	COG3719	Ribonuclease I	249
2919587614	281	98.57	1	279	1	275	5.5e-88	288.8	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
2919587616	430	97.99	37	410	4	345	0.0e+00	445.1	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
2919587617	228	89.64	24	228	22	220	9.6e-64	209.4	COG0692	Uracil DNA glycosylase	223
2919587618	512	93.37	13	509	20	512	3.8e-78	257.6	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
2919587619	317	68.82	58	309	32	223	1.4e-17	58.8	COG0500	SAM-dependent methyltransferase	257
2919587620	366	98.44	40	364	5	320	1.9e-110	363.2	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
2919587621	367	78.75	291	366	15	77	3.7e-09	29.8	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2919587624	301	60.92	34	292	116	313	8.3e-44	144.3	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2919587625	968	99.76	2	960	3	840	0.0e+00	1223.7	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
2919587626	139	65.43	5	136	50	155	1.1e-09	33.3	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2919587627	979	43.53	856	978	3	103	2.7e-53	78.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919587627	979	47.84	735	848	2	112	2.7e-53	97.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919587627	979	80.2	308	721	74	389	1.4e-76	253.1	COG0642	Signal transduction histidine kinase	336
2919587627	979	89.37	23	216	18	202	4.4e-24	78.4	COG5278	Extracellular (periplasmic) sensor domain CHASE3 (specificity unknown)	207
2919587628	410	96.51	14	394	13	371	0.0e+00	440.5	COG1485	Predicted ATPase	367
2919587629	200	62.96	7	194	35	136	1.6e-07	26.3	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2919587631	571	92.9	29	569	27	523	2.4e-129	426.4	COG3131	Periplasmic glucans biosynthesis protein	534
2919587632	690	81.79	22	689	42	643	0.0e+00	547.2	COG2943	Membrane glycosyltransferase	736
2919587633	125	95.89	2	121	6	145	1.2e-06	23.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919587635	411	97.23	22	404	10	395	1.5e-104	344.2	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2919587636	172	93.79	14	172	7	157	1.2e-37	123.4	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
2919587637	778	98.59	1	769	8	778	0.0e+00	970.2	COG2183	Transcriptional accessory protein Tex/SPT6	780
2919587642	316	99.05	3	315	2	313	4.4e-76	250.1	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2919587643	516	96.1	1	443	14	432	5.2e-84	276.5	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
2919587644	537	97.06	2	537	16	544	0.0e+00	453.6	COG0405	Gamma-glutamyltranspeptidase	539
2919587645	469	74.49	13	204	18	163	3.3e-08	28.2	COG4961	Flp pilus assembly protein TadG	185
2919587647	202	55.61	8	184	15	123	1.1e-14	49.2	COG4961	Flp pilus assembly protein TadG	185
2919587648	411	53.52	193	408	3	207	5.7e-25	41.9	COG0477	MFS family permease	338
2919587648	411	64.75	1	251	29	276	5.7e-25	44.2	COG0477	MFS family permease	338
2919587649	169	81.02	25	166	17	127	4.8e-11	36.5	COG1765	Uncharacterized OsmC-related protein	137
2919587650	255	96.81	1	246	4	246	1.4e-88	290.9	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2919587652	282	94.96	23	279	11	255	7.3e-74	242.7	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2919587653	328	94.33	1	323	6	321	4.5e-51	168.4	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919587654	930	97.69	28	910	14	860	0.0e+00	983.1	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
2919587655	204	86.22	2	194	26	194	4.8e-57	187.3	COG0576	Molecular chaperone GrpE (heat shock protein)	193
2919587657	250	97.88	7	250	5	235	1.2e-25	85.1	COG3637	Opacity protein and related surface antigens	199
2919587662	452	72.08	4	319	108	391	1.1e-57	190.4	COG0642	Signal transduction histidine kinase	336
2919587662	452	90.23	328	452	6	125	1.3e-13	42.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919587663	395	97.37	11	383	11	380	2.4e-89	294.1	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
2919587664	325	91.72	9	325	10	319	1.1e-69	229.1	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
2919587665	752	96.47	53	511	16	480	2.9e-68	217.3	COG3901	Regulator of nitric oxide reductase transcription	482
2919587666	338	25.06	223	331	83	183	3.0e-50	42.8	COG3391	DNA-binding beta-propeller fold protein YncE	381
2919587666	338	52.61	21	228	48	259	3.0e-50	120.6	COG3391	DNA-binding beta-propeller fold protein YncE	381
2919587667	418	13.93	246	377	292	342	1.3e-04	7.1	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919587667	418	35.52	75	240	51	180	1.3e-04	6.7	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919587668	142	56.71	6	142	50	142	2.1e-15	51.8	COG2010	Cytochrome c, mono- and diheme variants	150
2919587669	284	93.99	4	283	7	272	1.4e-23	76.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2919587670	589	78.27	6	588	149	753	8.7e-125	409.6	COG4993	Glucose dehydrogenase	773
2919587671	222	95.73	1	214	1	202	1.9e-51	169	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919587673	563	66.67	128	558	106	483	3.5e-38	126.2	COG1404	Serine protease, subtilisin family	508
2919587674	186	95.16	5	184	4	180	3.4e-45	148.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919587675	232	35.41	10	212	15	105	3.5e-03	10.7	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2919587676	220	93.19	15	209	12	189	1.4e-52	172.5	COG3672	Predicted transglutaminase-like cysteine proteinase	191
2919587677	107	20.78	16	91	10	73	2.4e-03	11.7	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
2919587678	176	85.14	2	147	14	139	3.9e-47	154.1	COG4957	Predicted transcriptional regulator	148
2919587679	481	30.57	372	448	95	142	1.4e-03	4.3	COG3352	Archaellum component FlaC	157
2919587679	481	38.85	228	307	32	92	1.4e-03	6.3	COG3352	Archaellum component FlaC	157
2919587679	481	45.87	2	117	130	240	8.0e-31	56.3	COG2202	PAS domain	232
2919587679	481	46.28	118	239	128	239	8.0e-31	43.7	COG2202	PAS domain	232
2919587680	89	62.96	5	86	31	81	1.4e-11	38.8	COG0236	Acyl carrier protein	80
2919587681	399	90.73	11	387	16	377	2.1e-27	90.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919587682	310	49.42	34	310	206	418	2.1e-22	73.7	COG0172	Seryl-tRNA synthetase	429
2919587683	307	88.99	3	306	32	314	2.6e-75	248.3	COG0657	Acetyl esterase/lipase	312
2919587684	267	97.74	10	265	7	265	6.7e-72	236.3	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919587685	244	97.76	1	243	6	267	8.8e-64	210	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919587686	466	63.22	122	465	187	535	1.0e-29	95.5	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2919587687	85	62.96	3	76	6	56	4.4e-06	21.1	COG0236	Acyl carrier protein	80
2919587693	346	89.97	8	346	33	346	0.0e+00	472.7	COG1613	ABC-type sulfate transport system, periplasmic component	348
2919587694	284	97.81	9	282	5	272	3.6e-103	338.5	COG0555	ABC-type sulfate transport system, permease component	274
2919587695	293	93.73	9	293	14	282	0.0e+00	441.5	COG4208	ABC-type sulfate transport system, permease component	287
2919587696	390	88.86	48	388	2	312	4.2e-124	408.7	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
2919587698	72	71.23	3	71	12	63	3.4e-12	40.5	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
2919587699	368	98.68	27	338	4	301	2.3e-104	342.8	COG0031	Cysteine synthase	300
2919587702	1793	96.51	176	1792	55	1630	0.0e+00	1191.4	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
2919587703	742	11.04	639	742	653	733	0.0e+00	30.9	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
2919587703	742	77.38	54	646	8	575	0.0e+00	684.2	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
2919587704	190	79.89	4	180	1	147	6.2e-34	111.7	COG0431	NAD(P)H-dependent FMN reductase	184
2919587705	31	32.91	1	30	16	41	1.0e-04	16.4	COG2155	Uncharacterized membrane protein YuzA, DUF378 family	79
2919587707	223	96.8	3	221	7	218	2.2e-86	282.9	COG3897	Predicted nicotinamide N-methyase	218
2919587709	412	95.51	2	364	8	347	8.9e-117	384.5	COG3569	DNA topoisomerase IB	354
2919587710	180	90.06	1	180	13	166	1.6e-28	94.3	COG3652	Predicted outer membrane protein	170
2919587716	188	91.98	30	187	8	156	1.7e-42	138.8	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
2919587718	136	42.86	14	132	7	63	8.2e-05	16.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919587719	416	97.78	10	416	10	405	0.0e+00	508.7	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
2919587720	244	94.26	1	244	13	242	1.2e-45	150.6	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
2919587721	140	76.74	3	138	17	148	1.4e-23	78	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2919587722	407	16.98	4	293	239	348	1.7e-03	10.3	COG1020	Non-ribosomal peptide synthetase component F	642
2919587723	260	92.82	3	219	11	178	3.5e-31	100.2	COG5342	Invasion protein IalB, involved in pathogenesis	181
2919587724	107	90.52	1	107	10	114	1.6e-46	151.7	COG3785	Heat shock protein HspQ	116
2919587725	349	99.3	29	340	1	283	1.1e-87	288.2	COG2301	Citrate lyase beta subunit	283
2919587726	436	57.05	85	400	14	195	1.8e-16	54.5	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2919587727	831	74.11	421	827	101	392	2.8e-65	216	COG0642	Signal transduction histidine kinase	336
2919587728	466	99.76	1	458	2	419	0.0e+00	654.4	COG0499	S-adenosylhomocysteine hydrolase	420
2919587730	541	97.83	16	541	1	540	0.0e+00	494.8	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2919587731	199	89.81	10	190	4	197	2.2e-19	62.5	COG0778	Nitroreductase	207
2919587734	424	93.99	191	385	12	183	3.2e-43	141.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919587735	247	68.97	3	246	38	306	1.9e-23	77.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919587736	466	8.53	236	418	50	86	7.9e-02	5.4	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2919587736	466	16.82	3	186	88	160	7.9e-02	6.4	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2919587737	715	39.74	381	707	45	199	5.2e-08	27	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919587739	528	96.09	28	484	5	446	4.8e-13	42.2	COG1538	Outer membrane protein TolC	457
2919587741	1593	73.48	948	1177	3	232	7.0e-43	139.3	COG1216	Glycosyltransferase, GT2 family	305
2919587741	1593	75.79	1185	1584	88	397	1.4e-15	51.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919587742	351	98.5	5	348	4	331	7.2e-100	328.9	COG2605	Predicted kinase related to galactokinase and mevalonate kinase	333
2919587743	211	96.05	19	195	6	175	3.2e-57	187.4	COG0279	Phosphoheptose isomerase	176
2919587744	410	56.36	13	248	2	165	7.9e-22	71.8	COG1209	dTDP-glucose pyrophosphorylase	286
2919587744	410	76.5	242	400	7	146	7.0e-46	149.9	COG0241	Histidinol phosphatase or a related phosphatase	181
2919587745	563	90.8	10	248	4	240	6.3e-71	137.6	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
2919587745	563	96.55	253	511	5	256	6.3e-71	93.5	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
2919587748	584	87.31	22	445	49	392	6.8e-55	181.4	COG0642	Signal transduction histidine kinase	336
2919587753	365	76.25	288	358	14	74	4.6e-12	39.1	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2919587756	191	90.86	7	177	11	179	3.1e-46	151.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919587757	361	81.37	7	349	55	351	2.0e-60	197.5	COG1858	Cytochrome c peroxidase	364
2919587759	244	33.69	12	237	94	187	8.4e-08	27.4	COG0500	SAM-dependent methyltransferase	257
2919587760	259	89.62	2	231	25	257	3.5e-40	132.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2919587761	230	89.95	14	230	16	203	2.7e-19	65.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919587762	320	98.41	4	318	2	311	3.6e-114	375.5	COG0039	Malate/lactate dehydrogenase	313
2919587763	31	7.83	1	31	1	30	2.4e-08	26.3	COG0045	Succinyl-CoA synthetase, beta subunit	387
2919587764	45	17.67	1	45	1	41	1.2e-07	25.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919587765	71	16.45	1	66	95	144	2.7e-03	11.8	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2919587771	353	71.16	3	311	10	236	8.0e-47	154.6	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2919587772	590	96.38	1	575	11	569	0.0e+00	706.9	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2919587773	304	24.11	135	304	400	534	7.9e-25	28.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919587773	304	28.57	2	170	293	452	7.9e-25	66.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919587776	452	97.44	22	443	9	388	1.7e-39	129.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919587778	169	60.55	11	167	12	143	1.5e-25	84.3	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919587780	301	98.24	38	297	3	281	3.2e-57	188.4	COG2801	Transposase InsO and inactivated derivatives	232
2919587782	108	82.91	1	108	8	104	2.4e-22	74.1	COG2963	Transposase and inactivated derivatives	116
2919587783	575	90.16	366	563	17	181	7.3e-52	168.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919587786	233	81.34	19	233	3	233	1.3e-46	153.8	COG2801	Transposase InsO and inactivated derivatives	232
2919587790	463	95.38	12	437	17	388	1.3e-29	96.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919587792	324	95.33	11	315	11	296	2.8e-52	172.1	COG2040	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)	300
2919587793	269	71.33	1	262	31	229	1.6e-21	71.8	COG0500	SAM-dependent methyltransferase	257
2919587794	291	77.67	6	289	58	304	9.5e-24	78.3	COG0657	Acetyl esterase/lipase	312
2919587795	210	20.42	27	173	315	411	6.8e-15	49.3	COG5361	Uncharacterized conserved protein	458
2919587798	413	98.23	12	413	3	391	0.0e+00	650.8	COG0133	Tryptophan synthase beta chain	396
2919587799	215	98.56	3	214	2	207	6.9e-60	196.9	COG0135	Phosphoribosylanthranilate isomerase	208
2919587800	120	66.33	4	90	33	97	3.0e-05	17.8	COG5416	Uncharacterized integral membrane protein	98
2919587801	103	96.81	1	94	2	92	1.9e-31	102.7	COG0776	Bacterial nucleoid DNA-binding protein	94
2919587802	327	88.12	1	317	9	290	5.4e-70	230.8	COG0616	Periplasmic serine protease, ClpP class	317
2919587803	572	99.45	12	561	2	548	0.0e+00	719.9	COG0539	Ribosomal protein S1	541
2919587805	238	99.13	1	238	2	229	1.1e-107	353.4	COG3820	Uncharacterized protein	230
2919587807	314	99.06	1	314	4	318	2.8e-123	405.6	COG0462	Phosphoribosylpyrophosphate synthetase	314
2919587809	70	97.1	1	70	1	67	1.7e-09	32.4	COG3585	Molybdopterin-binding protein	69
2919587810	522	98.88	18	466	2	441	0.0e+00	499.9	COG1570	Exonuclease VII, large subunit	440
2919587812	427	99.53	1	423	1	427	0.0e+00	538.2	COG0151	Phosphoribosylamine-glycine ligase	428
2919587814	716	66.52	146	711	213	653	0.0e+00	442.1	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919587815	307	97.29	15	307	7	293	4.1e-32	106.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919587816	234	92.91	3	231	7	255	2.7e-35	116.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919587817	154	93.46	5	151	10	152	1.2e-53	175.7	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2919587818	58	98.15	1	54	1	53	3.1e-20	66.6	COG5487	Uncharacterized membrane protein YtjA, UPF0391 family	54
2919587819	753	95.12	92	326	3	236	6.0e-74	242.5	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2919587820	189	97.34	1	184	2	184	3.0e-54	177.7	COG0742	16S rRNA G966 N2-methylase RsmD	187
2919587821	652	99.38	1	652	4	644	0.0e+00	560.5	COG0323	DNA mismatch repair ATPase MutL	638
2919587823	338	98.51	20	223	4	202	6.7e-75	245.1	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
2919587824	576	80.77	186	575	89	466	5.6e-75	246.9	COG5338	Uncharacterized protein	468
2919587826	267	97.87	26	267	3	232	2.8e-91	299.1	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
2919587827	604	99.65	12	588	2	565	0.0e+00	777.1	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2919587828	137	96.58	17	132	4	116	4.3e-26	85.4	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
2919587829	133	96.24	10	132	4	131	5.6e-27	88.8	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
2919587830	451	91.3	2	449	41	481	8.1e-36	117.9	COG0471	Di- and tricarboxylate transporter	461
2919587831	294	96.68	4	294	2	292	7.4e-57	187.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919587832	562	96.22	11	562	3	536	3.8e-107	353.4	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2919587833	445	95.71	33	437	15	416	6.6e-127	417.8	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
2919587834	152	76.62	28	151	4	121	5.3e-43	140.5	COG1321	Mn-dependent transcriptional regulator, DtxR family	154
2919587835	432	98.73	18	419	6	395	2.1e-92	304.1	COG0019	Diaminopimelate decarboxylase	394
2919587836	500	94.89	6	500	21	559	1.1e-104	345.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919587837	96	92.59	3	84	3	77	3.9e-14	47	COG0236	Acyl carrier protein	80
2919587838	310	92.9	2	301	13	326	4.9e-56	185	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2919587839	828	96.93	11	499	12	484	0.0e+00	488.4	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
2919587839	828	98.4	511	817	1	308	9.0e-51	167.3	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2919587840	1089	87.57	2	301	13	308	5.7e-56	185.2	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2919587840	1089	99.63	284	1088	1	805	0.0e+00	1185.7	COG4196	Uncharacterized conserved protein, DUF2126 family	808
2919587841	391	96.28	1	370	1	336	0.0e+00	440	COG4307	Uncharacterized protein	349
2919587842	523	88.08	228	509	7	272	1.5e-93	307.3	COG3285	Eukaryotic-type DNA primase	299
2919587844	153	89.36	3	140	5	130	1.7e-47	154.9	COG5478	Low affinity Fe/Cu permease	141
2919587847	409	96.74	12	409	10	395	4.0e-107	353.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919587848	87	86.87	1	86	11	96	9.6e-14	45.9	COG2388	Predicted acetyltransferase, GNAT superfamily	99
2919587853	120	11.68	95	119	113	128	1.2e-05	2.6	COG4319	Ketosteroid isomerase homolog	137
2919587853	120	33.58	5	86	19	64	1.2e-05	15.9	COG4319	Ketosteroid isomerase homolog	137
2919587854	147	75.52	18	139	35	142	9.6e-11	36.4	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2919587855	142	49.17	2	127	121	239	3.4e-17	57.1	COG2202	PAS domain	232
2919587856	416	98.5	1	416	6	400	2.5e-128	422.8	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2919587858	77	14.14	2	69	320	373	6.5e-04	13	COG3448	CBS-domain-containing membrane protein	382
2919587859	230	14.35	40	100	16	45	5.2e-21	10.7	COG0400	Predicted esterase	207
2919587859	230	58.85	86	226	81	203	5.2e-21	57.3	COG0400	Predicted esterase	207
2919587860	591	97.12	30	587	2	540	0.0e+00	454	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2919587861	281	84.02	1	280	29	312	5.1e-37	122.7	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2919587866	573	83.78	223	573	54	332	4.1e-64	211.3	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2919587867	231	98.17	10	215	3	216	3.1e-40	132.4	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919587868	770	31.73	195	437	56	180	6.9e-84	13.4	COG0642	Signal transduction histidine kinase	336
2919587868	770	80.2	382	768	77	392	6.9e-84	272.7	COG0642	Signal transduction histidine kinase	336
2919587869	123	92.48	1	123	6	128	1.1e-38	126.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919587870	381	92.21	109	380	7	231	2.0e-45	149.1	COG2114	Adenylate cyclase, class 3	227
2919587871	452	97.95	19	443	8	389	7.8e-38	124.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919587872	566	96.38	2	562	14	572	0.0e+00	700.9	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2919587877	163	28.75	1	160	300	460	2.1e-09	29.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919587878	238	96.05	18	233	6	224	1.2e-39	130	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919587879	133	66.92	9	123	6	94	3.4e-07	24.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919587881	100	56.25	13	97	32	94	3.1e-04	14.8	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
2919587882	221	85.92	10	219	27	209	8.2e-44	143.7	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2919587883	565	90.69	28	562	7	522	0.0e+00	614.9	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2919587884	355	84.25	3	227	21	234	2.2e-62	204.6	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2919587887	180	73.17	9	171	22	141	1.7e-08	28.6	COG2010	Cytochrome c, mono- and diheme variants	150
2919587889	453	95.76	29	453	14	397	2.4e-24	80.5	COG5557	Ni/Fe-hydrogenase 2 integral membrane subunit HybB	401
2919587890	940	6.91	538	663	715	770	1.2e-15	11.8	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2919587890	940	13.33	275	492	447	554	1.2e-15	22	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2919587890	940	13.46	6	250	3	111	1.2e-15	13.6	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2919587890	940	89.27	692	936	11	193	6.4e-43	140.6	COG0437	Fe-S-cluster-containing dehydrogenase component	203
2919587892	285	99.25	38	284	2	267	3.8e-71	234.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919587893	107	28.12	1	107	247	345	1.9e-27	90.8	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2919587894	94	23.3	2	91	160	241	2.3e-15	50.9	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2919587896	252	88.53	8	219	22	214	2.9e-25	83.3	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919587901	423	97.79	1	418	2	400	2.5e-52	172.7	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
2919587902	186	92.57	1	144	4	140	8.3e-45	146.6	COG4957	Predicted transcriptional regulator	148
2919587904	258	93.12	7	219	13	215	6.4e-28	92.1	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919587909	174	22.73	23	163	129	208	1.8e-02	8	COG1566	Multidrug resistance efflux pump	352
2919587919	422	62.11	1	405	6	282	6.0e-54	177.7	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2919587921	391	96.33	1	383	13	406	5.2e-39	129.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919587922	331	98.77	6	328	2	321	1.3e-79	262	COG2144	Selenophosphate synthetase-related protein	324
2919587923	181	56.13	26	164	23	109	1.0e-04	16.1	COG2153	Predicted N-acyltransferase, GNAT family	155
2919587924	389	98.82	33	384	4	338	3.8e-41	135	COG2516	Biotin synthase-related protein, radical SAM superfamily	339
2919587925	358	97.12	5	300	3	272	1.2e-48	159.9	COG0388	Predicted amidohydrolase	274
2919587927	464	98.03	16	457	4	450	8.6e-94	309.1	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2919587928	131	78.68	2	113	28	134	2.4e-33	109.3	COG3474	Cytochrome c2	135
2919587929	465	98.25	12	458	3	450	2.6e-94	310.9	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2919587930	125	86.51	1	111	17	125	2.9e-44	144.3	COG5349	Uncharacterized conserved protein, DUF983 family	126
2919587932	162	97.35	1	148	5	151	4.8e-50	163.9	COG1513	Cyanate lyase	151
2919587933	328	98.01	30	290	3	248	6.0e-88	288.9	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2919587934	279	94.19	1	278	9	251	2.0e-66	215.1	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2919587935	455	96.12	62	395	11	332	8.0e-74	243.1	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919587936	632	81	113	631	106	557	4.7e-123	406.3	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
2919587937	57	14.45	7	56	145	194	7.9e-09	29.2	COG0709	Selenophosphate synthase	346
2919587938	1435	27	240	469	208	386	0.0e+00	138.6	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919587938	1435	64.86	952	1426	210	639	0.0e+00	340.6	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919587940	100	89.58	4	96	6	91	1.1e-21	71.3	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
2919587941	348	81.13	176	331	15	143	2.7e-43	69.1	COG2030	Acyl dehydratase	159
2919587941	348	91.82	1	151	12	157	2.7e-43	72.2	COG2030	Acyl dehydratase	159
2919587942	267	96.14	5	253	4	252	1.7e-51	169.3	COG0730	Uncharacterized membrane protein YfcA	258
2919587944	362	20.71	127	292	397	512	8.2e-26	37.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919587944	362	25.18	2	129	311	451	8.2e-26	54.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919587945	147	85.71	16	147	6	119	2.7e-08	28.3	COG2346	Truncated hemoglobin YjbI	133
2919587946	156	97.74	22	146	3	132	1.2e-23	78	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919587947	158	68.15	18	152	8	114	1.1e-03	12.3	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2919587948	427	94.54	44	425	15	360	1.4e-103	341	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
2919587949	311	68.9	41	309	115	371	1.8e-83	275.2	COG2822	Iron uptake system EfeUOB, periplasmic (or lipoprotein) component EfeO/EfeM	376
2919587950	735	65.31	265	735	218	650	5.9e-99	326.2	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919587951	160	90.13	13	158	6	142	7.2e-28	91.6	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
2919587952	248	98.71	3	226	2	230	3.7e-69	226.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919587953	904	99	6	902	2	889	0.0e+00	1059.3	COG2205	K+-sensing histidine kinase KdpD	890
2919587954	201	98.94	1	198	2	188	1.5e-71	234.4	COG2156	K+-transporting ATPase, c chain	190
2919587955	701	99.41	2	701	3	680	0.0e+00	1093.3	COG2216	High-affinity K+ transport system, ATPase chain B	681
2919587957	571	99.46	2	561	3	559	0.0e+00	823.1	COG2060	K+-transporting ATPase, A chain	560
2919587960	458	97.52	22	457	4	435	1.5e-116	384.2	COG3182	Uncharacterized iron-regulated membrane protein	442
2919587961	768	98.62	4	768	12	795	3.3e-53	175.7	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2919587962	213	97.56	3	211	5	204	6.5e-51	167	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
2919587964	192	63.22	6	192	86	238	1.4e-53	177	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2919587966	419	98.21	7	389	6	388	3.3e-77	254.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919587967	1054	99.8	1	1026	2	1013	0.0e+00	1128.9	COG0841	Multidrug efflux pump subunit AcrB	1009
2919587968	413	93.11	2	411	27	418	8.9e-98	322.2	COG2124	Cytochrome P450	411
2919587969	465	98	1	464	6	445	6.9e-103	339	COG2610	H+/gluconate symporter or related permease	442
2919587970	148	90.84	17	148	6	124	8.1e-27	88	COG3788	Uncharacterized membrane protein YecN, MAPEG domain	131
2919587971	431	82.33	10	398	4	357	3.3e-55	182.4	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2919587972	84	98.53	17	78	2	68	3.5e-09	30.5	COG1141	Ferredoxin	68
2919587974	285	86.24	33	245	26	213	3.6e-16	53.6	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919587976	341	96.34	62	341	6	268	3.0e-77	254.2	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2919587977	343	72.46	45	328	15	235	3.1e-13	39.4	COG3301	Formate-dependent nitrite reductase, membrane component NrfD	305
2919587978	305	79.02	31	263	10	171	3.3e-52	171.1	COG0437	Fe-S-cluster-containing dehydrogenase component	203
2919587980	213	19.88	37	213	23	183	1.2e-23	77.6	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2919587981	863	76.05	1	850	192	807	4.9e-114	376	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2919587983	77	35.5	2	77	104	163	3.6e-07	25.2	COG5352	Uncharacterized protein	169
2919587984	336	98.75	1	335	2	318	2.2e-85	281.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919587985	286	97.21	1	282	8	286	4.4e-97	319.1	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2919587986	696	86.44	4	248	6	209	1.1e-20	69.1	COG3637	Opacity protein and related surface antigens	199
2919587987	161	91.55	17	155	13	142	3.1e-60	196.2	COG4101	Uncharacterized protein, RmlC-like cupin domain	142
2919587988	192	35.12	9	178	123	207	6.9e-09	30.2	COG2202	PAS domain	232
2919587989	212	76.15	21	193	44	209	5.5e-24	79.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919587992	331	92.31	3	331	25	336	1.2e-85	281.7	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
2919587994	171	94.77	1	171	7	169	1.5e-58	192	COG3656	Predicted periplasmic protein	172
2919587995	230	97.65	8	228	6	213	5.2e-63	206.9	COG3295	Uncharacterized protein	213
2919587996	227	98.69	1	227	4	229	2.4e-90	296.5	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
2919587997	744	85.73	64	744	79	721	6.4e-118	389	COG4774	Outer membrane receptor for monomeric catechols	750
2919587998	348	60.12	26	266	72	270	4.4e-31	102.1	COG0790	TPR repeat	292
2919588002	315	96.01	1	290	8	296	1.2e-56	187	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919588004	226	91.52	7	219	17	221	3.4e-40	132.1	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
2919588005	543	74.85	1	497	64	426	1.9e-52	172.9	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2919588006	266	97.67	6	252	4	254	6.3e-62	203.7	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2919588007	231	94.94	1	231	3	227	8.4e-85	278.1	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2919588008	266	95.7	15	266	9	253	1.6e-114	376	COG4674	ABC-type uncharacterized transport system, ATPase component	249
2919588009	386	95.98	16	362	8	317	4.6e-86	283.2	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2919588010	525	98.01	226	523	5	299	4.2e-98	322.7	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2919588011	440	98.91	21	401	3	364	2.6e-69	228.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919588012	318	92.88	1	304	22	308	2.7e-78	257.7	COG0010	Arginase family enzyme	305
2919588013	283	98.9	16	281	4	272	4.4e-56	184.7	COG0829	Urease accessory protein UreH	269
2919588014	209	95.69	6	209	6	205	6.1e-53	173.8	COG0400	Predicted esterase	207
2919588015	309	99.32	4	270	2	146	4.6e-33	103.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919588016	305	98.67	4	300	1	297	2.1e-70	232.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919588017	240	81.06	5	218	10	223	4.8e-15	49.6	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
2919588018	204	95.45	1	203	7	195	2.8e-74	243.3	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
2919588019	247	97.82	21	247	6	229	2.6e-65	215.1	COG0830	Urease accessory protein UreF	229
2919588020	170	98.72	1	169	1	154	9.3e-38	123.3	COG2371	Urease accessory protein UreE	155
2919588021	575	99.47	7	575	4	569	0.0e+00	1043.3	COG0804	Urease alpha subunit	568
2919588023	206	94.34	106	206	2	101	1.3e-44	144.3	COG0832	Urease beta subunit	106
2919588023	206	100	1	100	1	100	2.1e-50	163.2	COG0831	Urease gamma subunit	100
2919588033	329	60.56	12	280	25	219	3.7e-15	49.3	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
2919588037	270	90.21	10	270	24	281	4.2e-22	73.3	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2919588038	927	92.95	1	155	4	148	7.6e-44	142.8	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2919588038	927	98.66	160	914	7	741	0.0e+00	607.4	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919588040	601	97.77	13	600	11	581	0.0e+00	450	COG1001	Adenine deaminase	584
2919588041	308	94.03	11	304	13	264	2.8e-44	145.7	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2919588042	448	98.11	3	440	3	418	2.3e-99	327.1	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2919588043	410	95.22	8	407	20	417	5.1e-51	168.4	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2919588044	294	93.18	3	172	9	172	3.8e-57	187.1	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
2919588044	294	95.16	171	294	7	124	1.3e-40	132.4	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
2919588045	279	94.98	3	279	14	297	3.0e-63	208.2	COG3648	Uricase (urate oxidase)	299
2919588046	398	46.74	5	206	16	194	6.7e-22	59.5	COG0477	MFS family permease	338
2919588046	398	48.83	196	397	8	194	6.7e-22	18.7	COG0477	MFS family permease	338
2919588047	285	65.91	142	271	21	107	2.9e-14	46.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919588048	39	20.13	3	38	2	33	2.5e-03	12.1	COG1580	Flagellar basal body-associated protein FliL	159
2919588051	141	92.31	4	132	6	125	3.4e-34	111.9	COG5496	Predicted thioesterase	130
2919588052	153	91.22	1	149	7	141	1.3e-51	168.8	COG4957	Predicted transcriptional regulator	148
2919588056	327	83.58	22	310	3	226	2.7e-44	146.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919588057	267	79.49	6	267	54	270	3.5e-70	231.1	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2919588058	61	63.64	8	53	16	50	2.4e-05	18.4	COG3130	Ribosome modulation factor	55
2919588060	116	78.33	11	109	3	96	1.8e-20	67.5	COG3536	Uncharacterized conserved protein, DUF971 family	120
2919588061	581	98.76	6	563	2	560	7.6e-111	365.3	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2919588062	77	89.04	10	74	2	66	2.4e-11	37.4	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2919588063	323	36.83	197	322	85	214	2.4e-39	60.9	COG1413	HEAT repeat	335
2919588063	323	57.51	17	218	47	249	2.4e-39	82.6	COG1413	HEAT repeat	335
2919588065	148	65.18	1	148	5	150	3.2e-36	119	COG2323	Uncharacterized membrane protein YcaP, DUF421 family	224
2919588066	574	63.95	76	572	218	641	0.0e+00	453.8	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919588076	115	87.5	1	98	11	101	7.9e-15	48.9	COG4274	Uncharacterized protein, contains GYD domain	104
2919588083	205	96.32	15	205	6	188	1.5e-86	283.5	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
2919588084	159	91.61	1	153	12	153	3.6e-50	163.2	COG3043	Nitrate reductase cytochrome c-type subunit	155
2919588085	847	99.75	2	831	2	809	0.0e+00	703.3	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2919588086	109	81.91	22	108	6	82	1.1e-20	67.7	COG3062	Cytoplasmic chaperone NapD for the signal peptide of periplasmic nitrate reductase NapAB	94
2919588087	54	74.19	2	54	14	59	3.3e-20	66.2	COG4459	Periplasmic nitrate reductase system, NapE component	62
2919588088	56	36.17	1	40	26	59	3.0e-05	18.6	COG0776	Bacterial nucleoid DNA-binding protein	94
2919588089	338	87.88	183	312	13	128	4.7e-20	65.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919588092	370	86.36	223	365	14	127	1.4e-19	64.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919588093	140	65.85	19	140	36	143	1.3e-09	32.9	COG2010	Cytochrome c, mono- and diheme variants	150
2919588094	244	97.55	1	229	5	243	3.9e-62	204.1	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
2919588095	128	64.96	8	106	2	77	2.4e-09	31.9	COG2963	Transposase and inactivated derivatives	116
2919588096	174	60.92	11	174	43	215	8.3e-30	98.5	COG2801	Transposase InsO and inactivated derivatives	232
2919588097	62	15.85	1	60	237	281	5.1e-07	24	COG2801	Transposase InsO and inactivated derivatives	232
2919588100	372	95.38	3	366	15	386	4.5e-59	194.8	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919588101	1061	99.8	1	1029	1	1012	0.0e+00	1083.9	COG0841	Multidrug efflux pump subunit AcrB	1009
2919588102	278	88.15	1	249	31	268	3.9e-107	352.1	COG2326	Polyphosphate kinase 2, PPK2 family	270
2919588103	133	97.04	1	130	1	131	2.0e-25	83.7	COG0355	FoF1-type ATP synthase, epsilon subunit	135
2919588104	260	97.3	7	260	3	254	3.4e-93	306.1	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
2919588107	401	98.74	3	395	3	395	4.0e-127	418.6	COG0282	Acetate kinase	396
2919588108	324	22.02	18	97	3	74	3.2e-67	21.2	COG0280	Phosphotransacetylase	327
2919588108	324	70.03	83	316	97	325	3.2e-67	202	COG0280	Phosphotransacetylase	327
2919588110	173	73.46	9	172	37	155	1.1e-10	36.5	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2919588111	222	91.11	1	213	10	214	1.1e-87	287.5	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
2919588112	213	95.91	1	213	5	215	1.3e-77	254.4	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
2919588116	556	97.34	1	553	15	562	1.9e-114	377.5	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2919588119	811	98.36	3	796	13	792	0.0e+00	1330.3	COG3957	Phosphoketolase	793
2919588120	242	95.93	4	228	2	213	1.6e-40	133.5	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2919588121	774	20.31	6	179	10	166	0.0e+00	53.2	COG1554	Trehalose and maltose hydrolase (possible phosphorylase)	772
2919588121	774	67.92	225	762	242	766	0.0e+00	530	COG1554	Trehalose and maltose hydrolase (possible phosphorylase)	772
2919588122	531	99.45	5	530	2	542	5.8e-96	316	COG2985	Uncharacterized membrane protein YbjL, putative transporter	544
2919588123	803	98.32	9	781	4	763	0.0e+00	666.4	COG1554	Trehalose and maltose hydrolase (possible phosphorylase)	772
2919588124	329	97.86	1	325	6	325	5.6e-89	292.6	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2919588125	338	98.12	1	325	5	318	7.5e-96	315.3	COG0837	Glucokinase	320
2919588126	268	74.21	141	268	37	154	4.2e-16	53	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2919588126	268	79.87	1	143	8	134	4.2e-16	5	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2919588127	397	79.55	225	376	23	127	2.6e-18	59.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919588129	30	13.89	1	30	20	49	4.3e-08	27.5	COG3316	Transposase (or an inactivated derivative)	215
2919588130	240	64.13	12	231	71	306	9.4e-29	95.3	COG0457	Tetratricopeptide (TPR) repeat	291
2919588131	199	68.18	23	199	74	238	1.0e-54	180.6	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2919588140	456	98.53	28	454	4	405	3.9e-43	142.5	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
2919588141	325	63.8	58	302	42	219	2.4e-09	29.8	COG0500	SAM-dependent methyltransferase	257
2919588142	103	68	3	102	36	120	1.6e-14	48.8	COG3293	Transposase	124
2919588143	141	94.4	2	123	3	120	3.3e-24	80.1	COG3293	Transposase	124
2919588144	253	40.34	37	250	22	140	4.4e-04	15.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919588145	305	99.58	2	302	2	236	4.0e-24	78.2	COG3637	Opacity protein and related surface antigens	199
2919588147	417	97.55	1	415	2	399	1.1e-53	177.2	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
2919588148	262	8.65	228	262	312	341	9.9e-68	18.1	COG2951	Membrane-bound lytic murein transglycosylase B	343
2919588148	262	69.16	1	234	13	252	9.9e-68	208.2	COG2951	Membrane-bound lytic murein transglycosylase B	343
2919588149	141	90.4	2	129	3	115	1.1e-23	78.3	COG3293	Transposase	124
2919588150	114	82.4	2	112	17	119	4.5e-16	53.7	COG3293	Transposase	124
2919588155	170	80.47	39	166	25	127	2.2e-12	41.3	COG3755	Uncharacterized conserved protein YecT, DUF1311 family	127
2919588158	130	77.27	2	120	24	125	1.6e-19	64.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919588160	349	90.34	2	335	19	336	1.2e-79	261.6	COG1566	Multidrug resistance efflux pump	352
2919588161	341	14.87	197	333	410	511	4.8e-01	5.4	COG1289	Uncharacterized membrane protein YccC	674
2919588161	341	23.18	1	167	364	522	4.8e-01	4.6	COG1289	Uncharacterized membrane protein YccC	674
2919588162	454	93.48	4	316	14	314	1.6e-21	69.1	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
2919588163	63	30.94	12	62	6	48	7.9e-09	28.5	COG3415	Transposase	138
2919588166	124	94.4	1	124	6	123	6.4e-15	50.1	COG3293	Transposase	124
2919588167	132	94.4	1	120	6	123	1.8e-16	55.1	COG3293	Transposase	124
2919588172	223	83.79	2	223	3	214	2.6e-69	228.1	COG3926	Lysozyme family protein	252
2919588177	1797	18.72	963	1307	652	855	0.0e+00	36.1	COG4733	Phage-related protein, tail component	952
2919588177	1797	64.13	26	757	14	712	0.0e+00	718.8	COG4733	Phage-related protein, tail component	952
2919588178	188	96.02	1	179	5	197	5.3e-36	118	COG4723	Phage-related protein, tail component	198
2919588179	271	71.11	15	148	13	108	3.3e-03	9.3	COG1310	Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif	134
2919588180	242	94.81	5	242	12	230	1.3e-46	152.3	COG4672	Phage-related protein	231
2919588181	121	89.19	13	120	11	109	1.8e-18	60.9	COG4718	Phage-related protein	111
2919588184	909	82.67	128	902	155	898	4.3e-11	36.1	COG5281	Phage-related minor tail protein	833
2919588193	312	21.64	253	312	122	158	1.8e-05	2.8	COG4675	Microcystin-dependent protein  (function unknown)	170
2919588193	312	63.74	58	185	54	162	1.8e-05	12.8	COG4675	Microcystin-dependent protein  (function unknown)	170
2919588195	349	69.89	124	347	16	210	1.8e-06	21.8	COG0500	SAM-dependent methyltransferase	257
2919588196	220	17.43	4	49	8	45	5.7e-09	25.1	COG0572	Uridine kinase	218
2919588196	220	29.82	105	220	128	192	5.7e-09	2.9	COG0572	Uridine kinase	218
2919588199	303	68.99	4	285	28	274	1.6e-26	87.5	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2919588201	720	96.53	14	547	20	548	0.0e+00	804.6	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
2919588201	720	96.69	563	713	3	148	2.9e-57	187.1	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
2919588203	376	47.52	2	132	105	219	1.4e-27	33.1	COG2202	PAS domain	232
2919588203	376	58.26	124	268	102	242	1.4e-27	56.9	COG2202	PAS domain	232
2919588203	376	77.5	300	370	17	78	1.4e-16	53.5	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2919588208	374	93.77	3	371	3	348	9.1e-81	266.1	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
2919588212	897	55.2	775	893	15	83	1.5e-07	26.3	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2919588212	897	55.92	633	784	2	119	6.0e-15	48.8	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919588212	897	85.28	27	501	56	391	1.5e-79	262.8	COG0642	Signal transduction histidine kinase	336
2919588214	348	94.59	1	346	15	364	2.6e-97	320.4	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2919588215	470	29.08	15	196	8	64	5.1e-11	37.3	COG4961	Flp pilus assembly protein TadG	185
2919588216	189	46.43	1	157	5	95	3.0e-18	60.9	COG4961	Flp pilus assembly protein TadG	185
2919588218	242	87.2	19	236	27	210	9.9e-50	163.3	COG2173	D-alanyl-D-alanine dipeptidase	211
2919588222	205	68.86	2	203	79	277	1.1e-27	91.4	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
2919588223	295	97.97	13	294	5	293	7.5e-50	164.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919588225	372	94.36	2	365	19	386	3.3e-56	185.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919588226	765	73.77	1	765	1	748	0.0e+00	789.7	COG0841	Multidrug efflux pump subunit AcrB	1009
2919588227	294	25.84	1	262	752	1013	9.3e-85	279.6	COG0841	Multidrug efflux pump subunit AcrB	1009
2919588228	280	85.19	4	251	39	268	9.0e-107	350.7	COG2326	Polyphosphate kinase 2, PPK2 family	270
2919588229	135	96.3	1	130	1	130	2.5e-26	86.5	COG0355	FoF1-type ATP synthase, epsilon subunit	135
2919588230	260	97.3	7	260	3	254	3.7e-90	296.1	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
2919588233	401	98.24	3	395	3	393	3.9e-123	405.4	COG0282	Acetate kinase	396
2919588234	324	19.88	19	96	5	69	8.5e-61	14.8	COG0280	Phosphotransacetylase	327
2919588234	324	68.2	83	316	103	325	8.5e-61	187.5	COG0280	Phosphotransacetylase	327
2919588235	121	73.86	37	112	10	74	1.5e-03	12.5	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2919588236	178	80.25	7	163	24	153	1.3e-10	36	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2919588241	510	97.64	4	509	4	542	1.2e-106	346.7	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2919588242	739	99.33	14	729	5	744	0.0e+00	674.7	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919588243	323	98.6	1	323	1	282	4.8e-98	322.7	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2919588244	252	97.44	84	252	2	153	5.5e-67	218.6	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2919588245	245	92.47	51	226	6	177	2.1e-47	155.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919588246	276	97.52	4	276	5	279	7.9e-103	337.5	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2919588247	339	97.23	20	338	9	324	2.0e-125	412.4	COG0379	Quinolinate synthase	324
2919588248	507	96.92	2	498	8	511	0.0e+00	544.3	COG0029	Aspartate oxidase	518
2919588249	285	98.21	8	285	3	277	3.1e-107	352.1	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
2919588250	221	94.63	4	221	11	239	6.2e-55	181.2	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2919588251	139	96.67	3	122	3	118	1.1e-49	161.7	COG3536	Uncharacterized conserved protein, DUF971 family	120
2919588252	342	99.69	15	342	2	325	1.9e-117	386.1	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
2919588253	206	97.65	1	206	4	211	9.3e-39	127.8	COG3762	Uncharacterized membrane protein	213
2919588254	257	97.48	6	257	8	278	9.1e-61	195.3	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
2919588255	211	96.76	16	209	6	184	1.1e-66	217.9	COG1704	Uncharacterized conserved protein	185
2919588256	251	67.32	3	232	20	190	4.0e-21	70.3	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2919588257	100	91.92	7	100	4	94	2.0e-52	169.7	COG3526	Predicted selenoprotein, Rdx family	99
2919588258	736	94.74	371	717	8	223	9.1e-53	172.2	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919588259	330	93.81	4	328	20	322	6.8e-127	416.9	COG4111	Uncharacterized conserved protein	322
2919588260	227	96.21	4	220	5	207	1.1e-55	182.2	COG0352	Thiamine monophosphate synthase	211
2919588261	269	98.86	1	268	2	261	6.9e-103	337.7	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
2919588262	210	58.46	27	153	2	77	5.9e-19	63.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2919588263	194	91.71	2	194	15	202	1.1e-45	150.1	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
2919588264	360	77.84	1	357	1	288	2.4e-41	129.9	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2919588265	274	95.82	7	270	6	257	1.3e-106	349.9	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
2919588266	381	71.79	9	110	16	99	7.9e-07	22.4	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2919588266	381	96.25	113	381	10	266	3.7e-84	276.2	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2919588267	400	50.91	203	398	17	211	2.7e-06	7.9	COG0477	MFS family permease	338
2919588267	400	70.76	3	265	6	276	2.7e-06	8.6	COG0477	MFS family permease	338
2919588268	356	19.82	74	229	128	170	5.3e-05	14.9	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2919588269	146	100	1	146	1	144	5.3e-55	179.6	COG5458	Uncharacterized protein	144
2919588271	112	72.8	2	111	17	107	8.2e-07	23.5	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2919588272	106	98.06	1	105	1	101	1.6e-26	86.5	COG0633	Ferredoxin	102
2919588273	391	99.75	1	391	1	392	0.0e+00	587.6	COG3825	Uncharacterized conserved protein,  contains von Willebrand factor type A (vWA) domain	393
2919588275	613	75.78	406	582	22	190	1.4e-26	88.3	COG1226	Voltage-gated potassium channel Kch	212
2919588275	613	95.5	3	408	8	389	1.4e-80	265.2	COG0475	Kef-type K+ transport system, membrane component KefB	397
2919588278	283	80.61	1	274	19	284	1.8e-63	208.9	COG0714	MoxR-like ATPase	329
2919588279	326	97.5	1	323	1	312	1.5e-114	376.6	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2919588280	174	96.93	1	167	2	159	7.6e-42	137.2	COG2062	Phosphohistidine phosphatase SixA	163
2919588281	329	93.83	20	315	16	304	4.9e-54	177.5	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2919588282	157	94.52	1	139	8	145	8.5e-37	120.6	COG0071	Molecular chaperone IbpA, HSP20 family	146
2919588286	99	92.93	1	97	3	94	6.6e-12	39.6	COG1359	Quinol monooxygenase YgiN	100
2919588287	307	97.72	3	307	2	301	2.4e-111	366	COG0181	Porphobilinogen deaminase	307
2919588290	166	67.84	8	162	61	195	4.6e-44	145.3	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2919588291	324	79.55	7	319	51	260	5.1e-48	157.5	COG1729	Periplasmic TolA-binding protein (function unknown)	262
2919588292	382	71.1	6	260	26	244	1.9e-54	178.9	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
2919588293	640	99.17	9	605	2	597	0.0e+00	881	COG0465	ATP-dependent Zn proteases	596
2919588294	446	96.65	1	446	11	472	0.0e+00	461	COG1109	Phosphomannomutase	464
2919588295	112	89.52	1	112	10	120	1.3e-12	41.5	COG3801	Uncharacterized protein	124
2919588297	330	98.31	10	304	3	234	1.6e-29	97.7	COG3637	Opacity protein and related surface antigens	199
2919588298	313	97.46	2	313	7	236	4.3e-24	79.8	COG3637	Opacity protein and related surface antigens	199
2919588300	182	92.9	18	160	1	144	1.3e-29	97.2	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2919588301	917	90.61	71	861	44	815	0.0e+00	450.8	COG3264	Small-conductance mechanosensitive channel	835
2919588302	166	61.86	7	166	79	211	2.9e-14	47.2	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
2919588303	277	97.41	1	267	7	269	1.5e-45	150.5	COG1360	Flagellar motor protein MotB	244
2919588304	257	96.25	1	257	1	257	6.5e-64	209.8	COG1291	Flagellar motor component MotA	266
2919588305	592	99.16	4	580	4	590	0.0e+00	510.6	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2919588306	294	90.43	2	291	21	294	3.5e-52	171.7	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2919588307	799	96.05	392	657	6	224	1.7e-35	115.9	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919588308	601	85.12	1	600	116	773	0.0e+00	566.1	COG4993	Glucose dehydrogenase	773
2919588309	307	97.34	9	306	5	297	3.0e-40	132.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919588310	560	14.79	16	106	264	322	1.5e-122	10.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919588310	560	97.99	170	559	4	394	1.5e-122	398	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919588311	646	19.89	419	513	59	94	1.6e-04	10.8	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
2919588311	646	21.55	206	269	20	58	1.6e-04	3.3	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
2919588313	430	77.51	14	404	90	406	1.7e-33	110.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919588314	422	96.33	1	401	14	407	6.6e-32	105.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919588315	117	67.09	3	117	31	136	4.1e-15	50.6	COG5490	Uncharacterized protein	158
2919588316	278	26.58	141	192	112	153	4.4e-04	9.3	COG5490	Uncharacterized protein	158
2919588316	278	36.08	196	276	77	133	4.4e-04	14.1	COG5490	Uncharacterized protein	158
2919588317	484	18.63	384	465	261	328	1.2e-119	37	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2919588317	484	93.42	4	386	20	360	1.2e-119	361.3	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2919588320	302	95.51	1	280	11	308	8.5e-69	226.5	COG0501	Zn-dependent protease with chaperone function	302
2919588321	442	97.25	10	440	11	435	0.0e+00	576.4	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
2919588322	110	96.4	2	110	2	108	3.2e-32	105.6	COG3136	Uncharacterized membrane protein, GlpM family	111
2919588324	415	70.13	1	407	7	431	8.9e-57	183.2	COG0443	Molecular chaperone DnaK (HSP70)	579
2919588325	473	98.97	145	448	3	291	8.5e-73	239.5	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2919588327	233	96.4	1	215	5	218	4.4e-50	164.9	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2919588328	267	87.5	22	266	28	258	1.8e-84	277.2	COG5387	Chaperone required for the assembly of the mitochondrial F1-ATPase	264
2919588329	510	97.72	1	510	13	526	0.0e+00	722.3	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2919588332	310	97.95	12	299	5	291	2.1e-57	188.8	COG1408	Predicted phosphohydrolase, MPP superfamily	284
2919588334	465	98.88	1	453	3	444	0.0e+00	487.9	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2919588336	406	56.68	203	406	103	242	2.8e-53	175.5	COG3773	Cell wall hydrolase CwlJ, involved in spore germination	249
2919588338	328	99.7	4	327	2	331	7.5e-74	243.4	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2919588339	153	95.39	15	153	5	149	2.5e-31	103.1	COG0782	Transcription elongation factor, GreA/GreB family	151
2919588340	293	98.01	3	284	3	297	8.0e-53	174.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919588341	199	98.12	1	199	3	211	9.2e-56	183.5	COG0655	Multimeric flavodoxin WrbA	207
2919588342	335	93.4	12	222	13	210	2.8e-68	223.2	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
2919588343	591	97.24	12	452	7	394	5.6e-108	356.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919588344	259	95.47	1	254	7	259	3.2e-57	188.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919588345	283	87.31	4	280	2	235	1.2e-37	124.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919588346	286	97.01	3	254	2	261	1.7e-43	143.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919588347	334	91.46	10	334	29	328	3.7e-62	204.3	COG0598	Mg2+ and Co2+ transporter CorA	322
2919588348	506	90.8	249	485	4	240	1.6e-67	78.9	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
2919588348	506	92.72	7	252	3	244	1.6e-67	141.7	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
2919588349	362	89.91	122	362	18	222	3.3e-49	161.2	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919588350	251	98.67	1	226	1	223	1.4e-71	234.6	COG2135	Putative SOS response-associated peptidase YedK	226
2919588352	415	98.62	2	402	6	435	5.8e-77	253.7	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
2919588353	248	97.55	4	246	2	240	4.5e-83	272.5	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
2919588354	182	96.17	4	182	8	183	4.6e-41	135	COG2032	Cu/Zn superoxide dismutase	179
2919588355	455	47	239	448	9	188	1.2e-38	34.6	COG0477	MFS family permease	338
2919588355	455	62.92	22	278	8	248	1.2e-38	98.7	COG0477	MFS family permease	338
2919588357	364	98.55	17	363	3	342	6.8e-107	352.1	COG1420	Transcriptional regulator of heat shock response	346
2919588358	241	96.97	1	237	8	231	1.8e-95	313	COG0689	Ribonuclease PH	230
2919588359	209	96.92	7	208	3	191	4.4e-64	209.9	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
2919588360	388	90	3	388	37	414	1.6e-114	377.1	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
2919588362	105	21.59	22	101	102	166	4.5e-05	17.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919588364	401	92.9	34	386	9	348	9.3e-23	74.9	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919588365	318	97.79	34	311	4	269	8.6e-93	304.6	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
2919588366	127	96.49	13	124	3	112	1.6e-26	86.8	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
2919588367	129	92.48	9	129	6	128	4.1e-12	40.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919588368	313	94.67	9	309	15	298	3.4e-76	250.4	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
2919588369	404	95.07	174	404	6	217	1.0e-45	150.3	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
2919588370	243	85.2	27	243	22	211	9.1e-48	156.9	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
2919588372	367	84.3	127	367	37	240	4.5e-34	111.4	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2919588373	281	83.33	7	281	51	300	1.7e-56	186.7	COG3921	Uncharacterized conserved protein	300
2919588374	224	80.17	9	220	18	207	8.2e-20	64.8	COG0412	Dienelactone hydrolase	236
2919588375	693	97.8	17	693	15	682	0.0e+00	770.1	COG0339	Zn-dependent oligopeptidase	683
2919588378	294	93.85	2	288	16	305	1.1e-60	199.5	COG3386	Sugar lactone lactonase YvrE	307
2919588379	299	98.37	1	298	3	304	2.1e-55	182.2	COG0492	Thioredoxin reductase	305
2919588380	112	98.1	1	104	2	104	6.9e-46	148.8	COG0278	Glutaredoxin-related protein	105
2919588382	78	94.44	1	78	1	85	7.1e-25	81.6	COG0271	Stress-induced morphogen (activity unknown)	90
2919588383	741	97.75	2	726	16	755	0.0e+00	870.7	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
2919588385	617	99.17	4	611	3	599	0.0e+00	677.6	COG0514	Superfamily II DNA helicase RecQ	590
2919588386	401	98.9	24	397	3	361	1.9e-93	307.7	COG1195	Recombinational DNA repair ATPase RecF	363
2919588387	373	100	1	373	1	365	2.7e-117	386.4	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
2919588388	497	100	26	493	1	433	0.0e+00	462.3	COG0593	Chromosomal replication initiation ATPase DnaA	408
2919588389	92	98.86	1	88	1	87	4.4e-31	101.7	COG0268	Ribosomal protein S20	88
2919588390	337	98.71	28	329	2	306	1.7e-84	277.8	COG0010	Arginase family enzyme	305
2919588391	308	27.59	186	277	65	112	1.9e-18	7.7	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2919588391	308	78.74	22	191	23	159	1.9e-18	52.1	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2919588392	207	97.21	6	206	1	209	1.2e-42	140.6	COG0625	Glutathione S-transferase	211
2919588393	300	98.67	2	295	2	298	5.9e-66	217.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919588394	428	98	12	425	3	395	1.2e-130	430.1	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
2919588395	518	81.84	32	517	58	476	0.0e+00	488.3	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
2919588396	257	99.16	17	256	2	238	3.0e-86	282.7	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2919588398	303	100	1	295	1	274	2.2e-90	297.5	COG0266	Formamidopyrimidine-DNA glycosylase	273
2919588399	459	94.77	50	375	16	341	1.6e-96	317.2	COG1559	Cell division protein YceG, involved in septum cleavage	342
2919588400	288	98.62	1	288	5	290	1.7e-82	271.7	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
2919588401	230	96.92	14	218	4	192	8.0e-75	244.9	COG0194	Guanylate kinase	191
2919588402	196	92.86	3	192	12	193	1.1e-29	97.8	COG3230	Heme oxygenase	196
2919588403	867	96.53	140	867	11	734	0.0e+00	442.6	COG4251	Bacteriophytochrome (light-regulated signal transduction histidine kinase)	750
2919588404	464	99.12	2	455	4	454	4.6e-93	306.7	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2919588405	268	98.13	4	264	4	266	7.2e-59	193.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919588406	511	54.88	270	385	57	146	4.6e-29	45.9	COG2010	Cytochrome c, mono- and diheme variants	150
2919588406	511	67.07	4	119	55	164	4.6e-29	15.3	COG2010	Cytochrome c, mono- and diheme variants	150
2919588406	511	96.34	94	287	6	163	4.6e-29	43.2	COG2010	Cytochrome c, mono- and diheme variants	150
2919588408	164	92.55	8	160	10	158	6.1e-40	130.8	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
2919588409	395	93.37	7	386	2	381	3.9e-63	208.1	COG0644	Dehydrogenase (flavoprotein)	396
2919588410	444	48.04	228	441	13	196	4.6e-09	5.8	COG0477	MFS family permease	338
2919588410	444	71.02	3	322	46	317	4.6e-09	23.6	COG0477	MFS family permease	338
2919588411	253	79.66	1	246	49	279	2.1e-40	132.8	COG0382	4-hydroxybenzoate polyprenyltransferase	289
2919588412	448	38.02	238	413	124	215	9.2e-15	21.7	COG2202	PAS domain	232
2919588412	448	74.38	2	251	33	212	9.2e-15	29.1	COG2202	PAS domain	232
2919588413	251	91.19	15	246	20	226	7.7e-14	45.8	COG5012	Methanogenic corrinoid protein MtbC1	227
2919588415	428	22.71	225	415	248	351	6.4e-13	25.9	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2919588415	428	29.69	24	207	47	182	6.4e-13	14.8	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2919588416	518	73.14	9	421	97	431	2.0e-36	119.5	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2919588417	1236	32.54	762	1233	813	1274	0.0e+00	472.4	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
2919588417	1236	51.27	2	774	17	744	0.0e+00	495	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
2919588418	298	94.96	32	296	3	266	2.6e-84	276.9	COG1348	Nitrogenase subunit NifH, an ATPase	278
2919588419	235	45.49	9	219	58	168	5.0e-20	66.1	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2919588420	479	48.83	245	476	18	204	2.3e-04	8.3	COG0477	MFS family permease	338
2919588420	479	52.74	16	276	14	215	2.3e-04	9.5	COG0477	MFS family permease	338
2919588425	363	74.25	88	225	2	125	5.0e-03	10.5	COG1528	Ferritin	167
2919588427	405	100	1	394	1	390	0.0e+00	472.2	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
2919588428	380	78.72	37	379	10	342	6.3e-128	421.5	COG1239	Mg-chelatase subunit ChlI	423
2919588429	586	90.51	320	585	25	272	3.2e-55	181.3	COG1240	Mg-chelatase subunit ChlD	261
2919588430	311	97.97	29	301	2	290	8.5e-33	108.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919588431	488	95.77	1	482	8	483	1.7e-101	334.9	COG1233	Phytoene dehydrogenase-related protein	487
2919588432	357	94.81	18	295	11	284	5.5e-61	200.4	COG1562	Phytoene/squalene synthetase	288
2919588435	340	98.39	32	334	4	308	1.2e-96	318.1	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
2919588436	145	95.8	1	126	5	118	1.9e-33	109.3	COG0858	Ribosome-binding factor A	118
2919588438	979	99.29	473	979	3	559	0.0e+00	531.6	COG0532	Translation initiation factor IF-2, a GTPase	509
2919588439	266	87.37	21	115	5	87	3.7e-24	78.6	COG2740	Predicted RNA-binding protein YlxR, DUF448 family	95
2919588440	534	97.99	162	374	3	197	6.1e-83	270.7	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
2919588441	254	97.4	10	170	4	153	3.6e-41	134.7	COG0779	Ribosome maturation factor RimP	153
2919588444	344	99.4	2	332	2	335	0.0e+00	436.8	COG0136	Aspartate-semialdehyde dehydrogenase	334
2919588447	369	99.43	1	367	1	346	2.7e-124	409	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2919588448	328	76.52	26	323	5	255	2.0e-72	238.2	COG0142	Geranylgeranyl pyrophosphate synthase	322
2919588449	255	24.96	25	250	78	255	5.5e-64	211.2	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2919588451	412	98.76	5	411	4	401	0.0e+00	573.8	COG0137	Argininosuccinate synthase	403
2919588452	208	93.1	1	198	7	195	1.6e-49	162.6	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
2919588453	255	91.71	2	208	13	178	1.4e-31	103.4	COG5342	Invasion protein IalB, involved in pathogenesis	181
2919588454	231	66.67	28	225	83	248	1.0e-17	58.9	COG1651	Protein-disulfide isomerase	244
2919588455	190	96.07	11	187	6	176	2.9e-47	155.1	COG0712	FoF1-type ATP synthase, delta subunit	178
2919588456	509	99.21	1	509	1	500	0.0e+00	798.9	COG0056	FoF1-type ATP synthase, alpha subunit	504
2919588457	295	99.65	5	295	1	287	1.4e-100	331	COG0224	FoF1-type ATP synthase, gamma subunit	287
2919588458	485	99.15	11	484	3	466	0.0e+00	786.1	COG0055	FoF1-type ATP synthase, beta subunit	468
2919588459	133	97.04	1	130	1	131	4.6e-33	108.2	COG0355	FoF1-type ATP synthase, epsilon subunit	135
2919588460	418	54.22	15	351	10	234	8.1e-70	230.2	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
2919588461	85	56.86	3	76	31	88	7.4e-05	17.1	COG3162	Uncharacterized membrane protein, DUF485 family	102
2919588462	227	77.91	57	209	15	148	1.7e-22	74.2	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2919588463	195	89.32	1	195	16	199	6.2e-73	239.1	COG3816	Uncharacterized protein	205
2919588464	141	87.94	9	139	17	140	3.8e-19	63.1	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2919588465	334	95.15	13	334	11	324	3.1e-97	319.9	COG0714	MoxR-like ATPase	329
2919588466	303	62.59	1	297	153	413	1.1e-43	144.2	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2919588470	165	92.98	4	163	4	162	7.0e-45	147.1	COG3153	Predicted N-acetyltransferase YhbS	171
2919588473	367	99.45	1	366	2	363	0.0e+00	602.6	COG4174	ABC-type microcin C transport system, permease component YejB	364
2919588474	620	98.95	6	615	5	572	5.3e-125	412.4	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2919588475	632	95.82	8	626	21	570	1.6e-125	414.2	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2919588477	320	88.97	40	172	15	135	6.9e-44	142.7	COG3474	Cytochrome c2	135
2919588478	247	97.17	1	246	4	243	1.2e-89	294.1	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
2919588479	285	98.21	2	278	3	277	1.5e-79	261.5	COG0077	Prephenate dehydratase	279
2919588480	241	58.4	25	238	30	175	9.5e-19	62.2	COG2365	Protein tyrosine/serine phosphatase	249
2919588481	169	59.79	3	155	48	160	6.0e-12	40	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2919588482	179	98.84	1	175	2	171	1.5e-64	211.2	COG0221	Inorganic pyrophosphatase	171
2919588483	418	98.22	10	407	5	390	7.3e-90	296.5	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2919588484	289	98.62	1	289	4	289	1.2e-113	373.4	COG1946	Acyl-CoA thioesterase	289
2919588485	108	96.43	1	108	5	112	7.7e-46	149.6	COG0347	Nitrogen regulatory protein PII	112
2919588486	500	98.3	43	500	3	407	0.0e+00	521.9	COG0004	Ammonia channel protein AmtB	409
2919588488	530	98.47	1	326	4	324	1.1e-119	393.2	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2919588489	389	99.19	6	382	3	369	8.8e-104	341.5	COG1932	Phosphoserine aminotransferase	365
2919588491	246	92.62	15	246	3	228	2.5e-90	296.1	COG0336	tRNA G37 N-methylase TrmD	240
2919588492	247	48.75	25	240	43	178	1.5e-09	32.8	COG0500	SAM-dependent methyltransferase	257
2919588493	228	95.4	43	217	7	172	7.5e-38	124	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
2919588494	120	90	2	107	2	82	1.2e-34	112.2	COG0228	Ribosomal protein S16	87
2919588495	517	97.79	1	457	1	442	0.0e+00	586.4	COG0541	Signal recognition particle GTPase	451
2919588498	159	63.29	88	155	23	72	1.7e-02	10.6	COG3074	Cell division protein ZapB, interacts with FtsZ	79
2919588500	365	82.18	9	355	26	334	2.8e-42	138.2	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2919588501	353	93.58	88	353	6	253	5.4e-58	190.4	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
2919588502	546	81.41	65	541	78	423	5.9e-63	207.7	COG0840	Methyl-accepting chemotaxis protein	408
2919588503	562	13.84	421	559	140	192	1.5e-33	6.1	COG0477	MFS family permease	338
2919588503	562	22.19	256	359	8	92	1.5e-33	14.9	COG0477	MFS family permease	338
2919588503	562	75.46	6	290	2	290	1.5e-33	98.9	COG0477	MFS family permease	338
2919588504	562	99.63	32	554	2	535	0.0e+00	616	COG4147	Na+(or H+)/acetate symporter ActP	529
2919588505	125	93.14	24	125	5	99	3.3e-33	108	COG3162	Uncharacterized membrane protein, DUF485 family	102
2919588506	649	100	67	630	1	552	0.0e+00	817.1	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2919588507	849	85.03	442	849	56	390	8.6e-63	207.3	COG0642	Signal transduction histidine kinase	336
2919588508	162	78.48	4	139	30	153	7.1e-19	63	COG5490	Uncharacterized protein	158
2919588510	227	73.97	31	227	62	240	1.8e-56	186.3	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2919588511	315	90.24	3	297	14	318	1.0e-40	132	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2919588512	204	53.38	81	195	7	77	6.2e-12	39.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919588514	450	98.5	7	450	4	463	0.0e+00	532.5	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2919588515	622	99.17	18	614	5	603	0.0e+00	602.1	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2919588516	446	95.93	17	436	4	404	0.0e+00	523.7	COG1301	Na+/H+-dicarboxylate symporter	415
2919588520	75	25.57	1	63	95	139	1.9e-03	12.3	COG4740	Predicted metalloprotease	176
2919588522	614	95.28	17	472	20	443	3.0e-77	254.4	COG0038	H+/Cl- antiporter ClcA	443
2919588523	114	15.15	1	101	531	625	3.2e-21	69.6	COG1154	Deoxyxylulose-5-phosphate synthase	627
2919588526	712	65.99	129	571	129	388	5.1e-51	167.7	COG0642	Signal transduction histidine kinase	336
2919588527	500	82.67	281	499	31	216	9.2e-77	250.9	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2919588528	111	94.34	1	107	2	101	3.0e-30	98.8	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
2919588529	133	57.69	12	124	2	76	4.2e-15	51	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2919588530	442	96.47	4	441	2	438	0.0e+00	478.8	COG1797	Cobyrinic acid a,c-diamide synthase	451
2919588531	258	98.04	1	253	3	252	1.1e-104	343.4	COG2875	Precorrin-4 methylase	254
2919588532	133	36.79	2	128	201	317	2.7e-22	73.6	COG2073	Cobalamin biosynthesis protein CbiG	298
2919588533	426	98.57	29	235	1	207	1.0e-55	182.4	COG2241	Precorrin-6B methylase 1	210
2919588533	426	98.93	243	426	2	186	1.1e-60	197.9	COG2242	Precorrin-6B methylase 2	187
2919588534	244	96.11	1	242	3	249	2.8e-76	250.6	COG2099	Precorrin-6x reductase	257
2919588535	254	97.2	1	253	2	244	7.0e-86	282	COG1010	Precorrin-3B methylase	249
2919588536	261	99.15	22	261	2	234	2.0e-80	264	COG2243	Precorrin-2 methylase	234
2919588537	210	95.26	1	210	4	204	6.1e-75	245.8	COG2082	Precorrin isomerase	210
2919588538	445	32.68	5	222	30	197	2.3e-53	77.5	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2919588538	445	33.46	226	442	297	468	2.3e-53	96.7	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2919588539	1097	29.65	680	1088	838	1258	0.0e+00	394.9	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
2919588539	1097	50.63	7	686	12	730	0.0e+00	467.1	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
2919588540	198	94.5	1	183	9	197	1.4e-16	54.8	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
2919588541	344	97.24	7	343	1	317	1.8e-89	294.6	COG0523	GTPase, G3E family	323
2919588542	127	83.92	3	127	18	137	2.0e-37	122.6	COG5469	Predicted metal-binding protein	143
2919588543	254	96.67	1	250	4	235	3.3e-57	188	COG5446	Uncharacterized membrane protein, predicted cobalt tansporter CbtA	233
2919588546	176	98.86	7	171	2	174	7.7e-62	202.4	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
2919588547	200	99.49	3	200	2	198	8.2e-81	264.8	COG2109	ATP:corrinoid adenosyltransferase	198
2919588550	390	85.82	12	390	53	391	5.2e-26	85.4	COG2814	Predicted arabinose efflux permease, MFS family	394
2919588551	342	93.35	15	342	7	343	4.5e-67	220.7	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2919588552	330	97.5	8	330	5	316	2.8e-108	356	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
2919588553	484	99.38	1	484	2	484	0.0e+00	614.9	COG1492	Cobyric acid synthase	486
2919588554	506	92.78	6	504	31	557	7.7e-121	398.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919588555	385	97.69	76	373	3	298	2.7e-74	244.3	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2919588556	142	90.07	9	141	4	130	3.3e-53	173.5	COG0229	Peptide methionine sulfoxide reductase MsrB	140
2919588557	308	92.95	1	156	5	149	3.4e-11	37.7	COG2954	CYTH domain, found in class IV adenylate cyclase and various triphosphatases	156
2919588558	142	48.35	21	139	115	231	1.7e-17	58.6	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2919588559	464	97.13	17	442	4	409	0.0e+00	465.6	COG1301	Na+/H+-dicarboxylate symporter	415
2919588560	304	95.81	2	304	6	302	3.4e-73	240.9	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2919588561	338	66.95	113	302	9	168	2.3e-28	93.1	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2919588562	305	96.59	5	294	10	292	8.3e-102	334.5	COG0685	5,10-methylenetetrahydrofolate reductase	291
2919588563	1250	98.72	9	334	4	311	1.7e-123	405.8	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
2919588563	1250	99.77	335	1207	3	857	0.0e+00	1324.6	COG1410	Methionine synthase I, cobalamin-binding domain	842
2919588566	179	92.35	4	176	4	160	4.6e-35	115.5	COG1795	Formaldehyde-activating enzyme nesessary for methanogenesis	170
2919588568	1115	92.74	1	1100	3	1075	0.0e+00	964.4	COG0587	DNA polymerase III, alpha subunit	1139
2919588569	582	96.79	71	539	8	369	2.4e-26	86.1	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2919588570	268	90.42	21	267	9	244	6.4e-38	124.6	COG4544	Uncharacterized conserved protein	260
2919588572	405	99.02	4	402	4	406	1.7e-107	354	COG2081	Predicted flavoprotein YhiN	408
2919588573	340	98.05	61	330	2	252	1.9e-66	217.8	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2919588574	250	90.04	2	247	26	260	5.2e-83	272.7	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
2919588575	241	99.43	65	235	1	173	1.5e-33	110.8	COG1076	DnaJ-domain-containing proteins 1	174
2919588576	89	9.69	7	75	289	332	4.5e-02	7	COG3846	Type IV secretory pathway, TrbL components	452
2919588577	211	98.72	1	168	2	155	2.6e-25	83.4	COG2371	Urease accessory protein UreE	155
2919588580	539	92.94	70	539	30	424	1.0e-79	262.9	COG0840	Methyl-accepting chemotaxis protein	408
2919588581	505	92.48	16	505	33	438	1.8e-43	143.3	COG3659	Carbohydrate-selective porin OprB	439
2919588583	336	96.65	14	331	8	324	4.0e-40	131.9	COG0598	Mg2+ and Co2+ transporter CorA	322
2919588584	126	92.48	6	126	4	126	2.2e-15	51.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919588585	652	96.39	11	391	11	357	1.6e-75	248.1	COG0628	Predicted PurR-regulated permease PerM	355
2919588586	278	99.58	2	275	2	236	6.8e-23	74.8	COG3637	Opacity protein and related surface antigens	199
2919588588	255	42.62	11	188	60	163	1.4e-09	29.6	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2919588590	273	33.33	9	268	107	199	1.4e-08	29.5	COG0500	SAM-dependent methyltransferase	257
2919588591	317	89.54	1	314	17	307	1.0e-88	292	COG0042	tRNA-dihydrouridine synthase	323
2919588592	229	93.02	16	228	15	214	4.7e-49	161.5	COG3577	Predicted aspartyl protease	215
2919588593	70	67.57	4	68	6	55	2.6e-19	63.6	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
2919588594	276	97.19	18	276	4	245	1.7e-55	182.9	COG0368	Cobalamin synthase	246
2919588595	340	96.57	8	340	2	339	2.6e-107	353.2	COG2038	NaMN:DMB phosphoribosyltransferase	347
2919588596	511	86.8	44	488	48	389	7.1e-74	243.6	COG0642	Signal transduction histidine kinase	336
2919588597	151	96.15	1	151	4	153	3.3e-62	203.3	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2919588598	738	98.39	12	737	6	738	0.0e+00	466.6	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919588599	217	94.55	5	208	10	200	1.8e-46	152.4	COG1573	Uracil-DNA glycosylase	202
2919588600	231	94.17	2	231	10	235	2.0e-69	227.9	COG0284	Orotidine-5'-phosphate decarboxylase	240
2919588601	114	100	1	95	1	96	4.8e-31	101.4	COG5470	Uncharacterized conserved protein, DUF1330 family	96
2919588602	210	90.43	10	210	17	205	2.4e-21	71.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919588606	600	97.08	25	588	8	506	0.0e+00	563.1	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2919588607	588	98.83	18	588	8	597	0.0e+00	523.5	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
2919588608	167	96.2	1	152	6	157	5.6e-44	144.3	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2919588609	264	87.31	2	249	17	250	3.0e-61	201.3	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2919588610	313	93.28	9	313	19	268	1.8e-78	257.8	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2919588611	463	97.7	19	451	1	424	0.0e+00	591	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
2919588612	133	31.45	2	95	81	130	1.7e-03	13.5	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2919588615	339	96.79	11	333	7	338	1.1e-54	180.1	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2919588616	400	98.99	6	400	3	394	8.5e-129	424.4	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2919588618	192	96.43	5	186	4	192	4.9e-47	154.7	COG0693	Putative intracellular protease/amidase	188
2919588621	69	97.01	1	69	2	66	2.8e-32	105.1	COG1278	Cold shock protein, CspA family	67
2919588623	274	95.75	5	273	5	252	1.2e-56	186.3	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2919588625	316	97.59	19	310	7	289	1.4e-84	278	COG0382	4-hydroxybenzoate polyprenyltransferase	289
2919588627	250	98.78	6	248	3	245	1.5e-50	166.2	COG1385	16S rRNA U1498 N3-methylase RsmE	246
2919588628	455	99.78	1	455	1	455	0.0e+00	594.6	COG3572	Gamma-glutamylcysteine synthetase	456
2919588630	76	90	1	76	7	78	3.4e-21	69.5	COG0425	TusA-related sulfurtransferase	78
2919588631	190	90.7	25	185	8	163	2.6e-17	57.6	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2919588632	273	94.07	12	265	9	246	8.6e-44	143.7	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
2919588633	498	97.42	15	477	9	461	2.3e-97	320.7	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2919588634	357	67.97	3	350	108	385	2.0e-14	48.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919588635	678	74.08	220	595	92	394	4.9e-22	73.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919588636	185	96.47	6	172	4	167	5.9e-61	199	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
2919588638	368	92.93	55	359	14	289	2.9e-92	303.3	COG1533	DNA repair photolyase	297
2919588639	199	91.09	14	197	2	185	3.4e-48	158.8	COG0164	Ribonuclease HII	199
2919588640	354	97.07	1	330	2	398	8.5e-33	109	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919588641	277	99.17	14	251	1	239	1.6e-72	238.1	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
2919588643	402	98.43	3	396	6	382	3.2e-119	392.6	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
2919588644	314	98.17	3	314	2	322	5.0e-93	305.9	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2919588646	208	98.56	1	207	4	208	2.4e-66	217.6	COG3404	Formiminotetrahydrofolate cyclodeaminase	208
2919588647	392	99.74	1	388	1	382	0.0e+00	509.1	COG0045	Succinyl-CoA synthetase, beta subunit	387
2919588648	297	99.32	1	296	1	292	5.1e-116	381.4	COG0074	Succinyl-CoA synthetase, alpha subunit	293
2919588649	920	92.33	28	920	71	913	0.0e+00	739.4	COG2352	Phosphoenolpyruvate carboxylase	910
2919588650	324	97.89	16	324	2	280	2.1e-90	297.2	COG2301	Citrate lyase beta subunit	283
2919588651	105	39.58	2	95	54	110	9.2e-05	16.9	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
2919588652	144	94.33	1	136	7	139	2.3e-42	139	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2919588656	288	92.45	23	279	13	257	2.1e-43	142.5	COG2116	Formate/nitrite transporter FocA, FNT family	265
2919588657	246	95.72	7	246	2	247	1.3e-61	202.6	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
2919588658	238	97.45	1	237	1	229	5.0e-73	239.8	COG1489	DNA-binding protein, stimulates sugar fermentation	235
2919588660	254	93.22	1	253	4	278	9.2e-35	114.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919588661	253	84.64	3	252	45	292	1.7e-22	74.4	COG0842	ABC-type multidrug transport system, permease component	286
2919588662	308	99.35	1	306	2	305	3.2e-91	300.4	COG1131	ABC-type multidrug transport system, ATPase component	293
2919588663	162	93.79	1	159	8	158	3.2e-35	115.6	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2919588664	193	95.03	37	192	3	155	5.1e-31	101.8	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2919588665	75	90	1	75	8	79	7.0e-21	68.7	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
2919588666	251	98.02	1	250	4	250	1.3e-61	202.7	COG0356	FoF1-type ATP synthase, membrane subunit a	246
2919588667	125	81.03	14	124	4	97	6.6e-27	88.2	COG5336	FoF1-type ATP synthase assembly protein I	116
2919588668	217	71.49	11	216	70	247	2.0e-36	120.2	COG1651	Protein-disulfide isomerase	244
2919588669	161	86.19	1	160	24	179	5.4e-37	122	COG5389	Uncharacterized protein	181
2919588670	96	56.7	13	84	12	66	1.1e-10	36.1	COG2314	Uncharacterized membrane protein YozV, TM2 domain	95
2919588671	440	95.76	4	352	12	350	1.7e-105	347.6	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
2919588672	391	97.96	14	361	1	336	5.1e-88	289.8	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2919588673	276	96.41	33	276	4	245	7.2e-84	275.5	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2919588674	263	96.9	5	261	7	256	1.7e-86	284.2	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2919588675	333	95.52	16	333	4	323	4.9e-60	198	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919588676	316	94.03	1	315	8	322	3.6e-66	218	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919588677	199	90.22	4	181	2	167	3.2e-36	119.1	COG0431	NAD(P)H-dependent FMN reductase	184
2919588679	210	81.82	7	205	4	174	8.8e-25	82.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919588680	414	96.15	1	391	9	383	2.9e-45	149.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919588681	1032	99.8	4	1002	1	1012	0.0e+00	983.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2919588682	339	98.49	6	339	5	330	3.9e-87	287	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2919588684	290	98.88	42	288	2	266	6.9e-65	213.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919588685	162	94.01	1	162	5	161	7.3e-60	196.2	COG3685	Ferritin-like metal-binding protein YciE	167
2919588686	1111	93.07	10	1097	22	1082	0.0e+00	907	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
2919588687	757	97.36	1	757	22	795	2.7e-109	361.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2919588688	529	19.86	368	502	338	425	4.3e-47	2	COG3182	Uncharacterized iron-regulated membrane protein	442
2919588688	529	86.91	1	373	1	385	4.3e-47	155.6	COG3182	Uncharacterized iron-regulated membrane protein	442
2919588690	627	82.41	3	608	135	771	1.2e-102	335.6	COG4993	Glucose dehydrogenase	773
2919588691	303	89.4	5	293	6	258	2.9e-08	25.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2919588692	196	64.02	11	181	59	163	4.1e-13	44.2	COG2010	Cytochrome c, mono- and diheme variants	150
2919588694	344	96.36	5	344	12	329	3.9e-55	181.6	COG0714	MoxR-like ATPase	329
2919588695	280	46.04	43	278	200	391	7.2e-10	32.8	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2919588698	196	25.82	6	185	228	322	7.6e-04	14.4	COG0457	Tetratricopeptide (TPR) repeat	291
2919588701	314	26.8	22	143	120	227	2.6e-37	29.4	COG3391	DNA-binding beta-propeller fold protein YncE	381
2919588701	314	48.14	113	308	62	255	2.6e-37	100.3	COG3391	DNA-binding beta-propeller fold protein YncE	381
2919588703	230	96.68	1	209	3	206	1.4e-35	117.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919588704	318	94.93	1	317	2	319	5.6e-59	194.5	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919588705	457	97.48	7	457	4	468	5.7e-102	336.3	COG4529	Uncharacterized NAD(P)/FAD-binding protein YdhS	474
2919588706	91	89.41	1	81	7	82	4.4e-27	88.1	COG3750	Uncharacterized conserved protein, UPF0335 family	85
2919588707	328	97.81	1	326	6	317	3.3e-94	310	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919588708	171	18.03	20	156	83	137	1.2e-01	3.3	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2919588709	508	97.62	1	501	1	492	0.0e+00	623.3	COG3333	TctA family transporter	504
2919588710	250	89.45	1	237	14	242	2.3e-40	131.5	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2919588713	266	95.47	2	264	9	261	1.6e-67	221.9	COG0300	Short-chain dehydrogenase	265
2919588715	273	97.63	1	273	6	293	3.6e-49	162.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919588716	125	92.48	5	125	4	126	3.9e-16	53.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919588717	55	7.01	12	51	191	217	8.4e-06	19.7	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2919588718	298	95.49	1	292	12	286	3.6e-60	198.3	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
2919588719	192	71.29	2	172	49	197	2.8e-23	76.9	COG0406	Broad specificity phosphatase PhoE	208
2919588720	96	96.88	1	96	2	94	1.1e-19	65	COG5470	Uncharacterized conserved protein, DUF1330 family	96
2919588721	160	98.68	1	152	3	151	3.0e-45	148.5	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
2919588723	382	90.23	4	360	13	372	1.1e-32	107.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919588724	245	78.86	17	241	11	204	7.2e-37	121.6	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
2919588725	205	57.35	4	202	16	175	9.4e-12	40.1	COG0500	SAM-dependent methyltransferase	257
2919588726	992	52.07	405	526	117	242	2.4e-94	69.1	COG2202	PAS domain	232
2919588726	992	57.85	517	655	103	242	2.4e-94	55.6	COG2202	PAS domain	232
2919588726	992	58.26	270	407	102	242	2.4e-94	94.9	COG2202	PAS domain	232
2919588726	992	58.26	645	784	102	242	2.4e-94	79.1	COG2202	PAS domain	232
2919588726	992	72.73	36	281	67	242	2.4e-94	56.5	COG2202	PAS domain	232
2919588729	289	89.04	1	269	29	296	2.3e-45	150	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919588731	178	97.89	22	176	3	141	1.9e-50	164.4	COG4101	Uncharacterized protein, RmlC-like cupin domain	142
2919588732	314	91.04	1	313	8	312	4.3e-54	178.4	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919588733	372	94.46	13	359	17	340	5.3e-67	220.7	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2919588734	398	94.74	18	398	17	394	5.0e-52	171.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919588736	264	67.46	1	257	67	292	2.4e-21	70.7	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919588737	338	95.74	78	335	9	255	4.9e-53	174.1	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2919588738	270	96.81	23	270	4	246	8.3e-91	298.4	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2919588739	325	96.86	35	318	7	284	7.0e-88	288.8	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2919588740	413	43.13	241	413	74	164	4.4e-13	8.2	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
2919588740	413	86.73	22	243	17	199	4.4e-13	41.3	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
2919588743	135	41.81	36	135	134	230	8.5e-10	32.5	COG3039	Transposase and inactivated derivatives, IS5 family	230
2919588744	142	92	3	126	8	122	6.4e-17	56.5	COG3293	Transposase	124
2919588745	283	96.41	12	264	5	246	1.0e-90	297.8	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2919588746	287	95.74	24	284	10	256	3.2e-72	237.3	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2919588747	472	97.31	3	377	7	332	2.1e-55	180.1	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919588748	254	95.41	20	244	8	215	8.0e-32	105	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919588749	141	60.58	45	140	39	101	1.9e-03	12.2	COG4274	Uncharacterized protein, contains GYD domain	104
2919588753	246	93.58	12	226	13	216	1.2e-27	91.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919588757	421	51.44	1	194	9	205	2.3e-20	45.5	COG0477	MFS family permease	338
2919588757	421	54.31	205	417	3	210	2.3e-20	27.9	COG0477	MFS family permease	338
2919588758	72	33.33	5	67	54	108	1.0e-03	13.4	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
2919588759	201	88.71	3	186	17	181	1.1e-26	87.7	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
2919588761	346	89.03	1	338	10	293	2.1e-45	149.8	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2919588762	386	77.51	1	384	100	447	3.4e-54	178.4	COG2610	H+/gluconate symporter or related permease	442
2919588765	373	86	1	373	55	404	1.5e-72	239.1	COG1228	Imidazolonepropionase or related amidohydrolase	406
2919588769	116	92.74	1	114	7	121	3.7e-29	95.4	COG3801	Uncharacterized protein	124
2919588770	69	98.51	1	69	1	66	7.6e-35	113.3	COG1278	Cold shock protein, CspA family	67
2919588771	120	26.55	5	120	142	244	1.5e-01	5.3	COG3064	Membrane protein involved in colicin uptake	387
2919588773	195	40.51	3	81	14	77	6.2e-06	3.7	COG5490	Uncharacterized protein	158
2919588773	195	77.85	50	190	21	143	6.2e-06	21	COG5490	Uncharacterized protein	158
2919588776	247	78.44	7	216	46	216	1.9e-16	54.5	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919588778	140	87.16	1	134	16	144	3.0e-46	151.4	COG4957	Predicted transcriptional regulator	148
2919588780	324	80.3	187	321	20	125	6.7e-20	64.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919588783	391	100	1	391	1	353	9.4e-114	374.2	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2919588785	255	94.5	26	242	12	217	9.6e-31	101.3	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919588787	421	85.33	1	287	24	279	1.5e-51	169.6	COG2342	Endo alpha-1,4 polygalactosaminidase, GH114 family (was erroneously annotated as Cys-tRNA synthetase)	300
2919588789	626	42.15	30	157	141	242	6.2e-25	22.8	COG2202	PAS domain	232
2919588789	626	56.61	153	295	106	242	6.2e-25	29	COG2202	PAS domain	232
2919588789	626	80.99	207	420	41	236	6.2e-25	55.1	COG2202	PAS domain	232
2919588789	626	96.04	421	618	7	200	8.4e-46	149.9	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2919588791	247	93.37	16	245	10	192	3.4e-38	125.7	COG0693	Putative intracellular protease/amidase	188
2919588792	324	85.09	6	324	49	322	1.6e-44	146.7	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
2919588793	586	92.21	347	585	9	233	3.6e-42	139	COG2114	Adenylate cyclase, class 3	227
2919588799	432	20.12	33	277	249	483	1.1e-20	32.8	COG1196	Chromosome segregation ATPase	1163
2919588799	432	20.8	163	412	669	911	1.1e-20	48.4	COG1196	Chromosome segregation ATPase	1163
2919588801	110	15.15	1	101	531	625	2.9e-21	69.8	COG1154	Deoxyxylulose-5-phosphate synthase	627
2919588802	341	98.13	10	340	4	318	4.5e-55	181.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919588803	298	76.82	9	261	20	241	5.6e-38	125.2	COG1562	Phytoene/squalene synthetase	288
2919588804	284	84.08	16	280	19	261	5.2e-54	177.9	COG1562	Phytoene/squalene synthetase	288
2919588806	665	98.07	112	657	9	515	3.9e-98	323.4	COG1657	Squalene cyclase	517
2919588807	260	16.46	38	133	68	106	2.9e-15	26.1	COG0775	Nucleoside phosphorylase	234
2919588807	260	23.63	100	213	152	207	2.9e-15	25.7	COG0775	Nucleoside phosphorylase	234
2919588808	387	86.03	10	315	16	323	1.6e-30	100.6	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2919588809	883	11.97	1	105	2	89	4.1e-55	21.2	COG1033	Predicted exporter protein, RND superfamily	727
2919588809	883	12.79	438	558	9	102	4.1e-55	2.3	COG1033	Predicted exporter protein, RND superfamily	727
2919588809	883	25.17	210	429	549	733	4.1e-55	88.2	COG1033	Predicted exporter protein, RND superfamily	727
2919588809	883	25.85	590	851	537	726	4.1e-55	72	COG1033	Predicted exporter protein, RND superfamily	727
2919588810	280	60.31	1	277	3	157	6.9e-32	105.1	COG3394	Predicted glycoside hydrolase or deacetylase ChbG, UPF0249 family	257
2919588811	477	63.05	51	473	126	439	8.9e-38	124.9	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
2919588812	394	55.64	2	282	27	307	7.9e-15	48.1	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2919588813	205	95.05	3	195	10	201	1.3e-21	71.7	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
2919588814	370	86.11	2	315	19	297	4.6e-11	36.7	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2919588815	393	87.31	80	383	34	267	5.7e-18	57.1	COG1834	N-Dimethylarginine dimethylaminohydrolase	267
2919588817	203	95.35	1	203	1	205	3.2e-31	103.3	COG0625	Glutathione S-transferase	211
2919588818	393	53.77	2	262	33	203	5.5e-07	23.5	COG0657	Acetyl esterase/lipase	312
2919588820	149	24.84	8	132	6	121	4.1e-13	43.2	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2919588822	163	94.44	38	162	2	120	5.2e-41	133.7	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
2919588823	184	94.03	18	84	3	65	6.7e-40	56.5	COG1278	Cold shock protein, CspA family	67
2919588823	184	97.01	110	176	2	66	6.7e-40	71.4	COG1278	Cold shock protein, CspA family	67
2919588824	336	88.65	11	329	10	298	1.9e-66	218.7	COG3503	Uncharacterized membrane protein	323
2919588825	188	98.47	1	130	3	131	5.3e-43	140.2	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
2919588826	351	99.07	3	349	3	321	0.0e+00	435	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
2919588827	349	92.7	1	349	24	366	3.1e-119	392.3	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
2919588828	246	98.37	3	231	4	244	1.5e-62	205.4	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
2919588829	206	93.49	3	205	3	203	2.5e-56	185.2	COG0625	Glutathione S-transferase	211
2919588830	220	92.45	3	209	11	206	5.2e-28	91.6	COG0684	Regulator of RNase E activity RraA	210
2919588831	279	99.13	16	255	2	230	2.1e-38	126.5	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
2919588833	244	95.73	9	240	4	227	1.3e-77	254.7	COG3821	Uncharacterized membrane protein	234
2919588834	94	96.77	2	93	3	92	1.9e-26	87	COG1254	Acylphosphatase	92
2919588835	143	78.33	3	109	5	98	7.2e-07	23.8	COG2105	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family	120
2919588836	667	99.85	1	667	1	645	0.0e+00	896.3	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2919588837	441	96.72	243	428	5	181	1.3e-50	166	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919588839	309	90.2	1	309	4	316	3.4e-107	352.8	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2919588840	127	98.45	1	127	3	129	7.9e-38	124.2	COG4922	Predicted SnoaL-like aldol condensation-catalyzing enzyme	129
2919588841	277	55.91	3	259	31	186	7.7e-14	46.9	COG0500	SAM-dependent methyltransferase	257
2919588842	358	87.76	204	358	2	173	2.0e-25	83.7	COG0807	GTP cyclohydrolase II	193
2919588842	358	98.03	2	204	4	202	2.3e-80	262.8	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
2919588843	368	95.95	2	366	2	356	0.0e+00	529.7	COG0082	Chorismate synthase	369
2919588844	286	97.67	1	286	5	298	3.7e-43	142.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919588846	375	98.13	1	375	5	371	7.7e-107	352.3	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
2919588847	425	98.51	11	425	6	403	7.5e-129	424.7	COG0162	Tyrosyl-tRNA synthetase	401
2919588849	155	97.45	1	155	3	155	3.3e-62	203.4	COG1225	Peroxiredoxin	157
2919588850	380	77.22	36	373	64	307	3.4e-50	166	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2919588851	321	99.16	72	310	2	238	2.9e-113	371.2	COG1186	Protein chain release factor B	239
2919588855	411	98.23	11	397	5	393	1.0e-122	404.2	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2919588857	597	99.56	140	595	2	451	0.0e+00	622.5	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
2919588858	450	97.3	7	434	13	444	4.4e-68	224.1	COG2067	Long-chain fatty acid transport protein	440
2919588859	294	88.64	12	281	30	271	1.7e-86	284.5	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2919588860	336	91.42	11	331	12	320	3.7e-118	388.5	COG0502	Biotin synthase or related enzyme	335
2919588861	499	85.28	39	497	56	391	7.7e-42	138.7	COG0642	Signal transduction histidine kinase	336
2919588862	240	78.57	1	231	13	188	2.0e-34	113.3	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
2919588863	217	62.76	9	175	14	163	5.0e-21	69	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2919588864	387	98.88	10	377	3	355	2.2e-122	403.1	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
2919588866	226	95.52	1	222	2	214	3.2e-42	139.1	COG1843	Flagellar hook assembly protein FlgD	222
2919588868	538	97.63	1	538	14	548	0.0e+00	432.8	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
2919588869	329	95.88	1	328	14	339	5.0e-87	286.8	COG1536	Flagellar motor switch protein FliG	339
2919588870	199	65.43	10	179	59	217	1.2e-12	42.2	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
2919588871	111	59.57	1	106	58	141	7.3e-33	108.7	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
2919588872	456	93.58	2	443	21	457	0.0e+00	458.8	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2919588874	436	93.55	66	436	23	370	2.0e-69	228.8	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
2919588876	350	83.95	11	342	24	295	7.2e-11	36.3	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2919588877	268	85.14	22	267	37	248	4.2e-92	302.4	COG1338	Flagellar biosynthetic protein FliP	248
2919588878	1099	43.75	510	1053	63	223	1.0e-03	11.8	COG0457	Tetratricopeptide (TPR) repeat	291
2919588880	225	91.71	1	223	12	177	2.1e-29	95.5	COG5342	Invasion protein IalB, involved in pathogenesis	181
2919588882	481	99.38	3	480	3	480	0.0e+00	794.7	COG5310	Homospermidine synthase	481
2919588883	92	30	1	68	1	60	3.9e-05	17.5	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
2919588885	307	96.57	5	306	4	313	6.3e-48	158.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919588886	682	88.14	2	501	65	547	0.0e+00	510	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
2919588886	682	91.39	512	662	10	147	6.1e-42	136	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
2919588887	428	97.89	34	405	2	325	1.7e-79	261.6	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2919588889	200	96.89	1	199	1	187	7.7e-78	255.1	COG0066	3-isopropylmalate dehydratase small subunit	191
2919588890	396	89.63	1	327	34	344	9.3e-107	351.5	COG2951	Membrane-bound lytic murein transglycosylase B	343
2919588891	84	88.37	1	81	3	78	1.3e-19	64.2	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
2919588892	90	97.62	1	88	3	84	8.5e-33	106.9	COG4115	Toxin component of the Txe-Axe toxin-antitoxin module, Txe/YoeB family	84
2919588893	130	94.26	1	116	7	121	9.3e-51	165.3	COG0335	Ribosomal protein L19	115
2919588894	188	87.1	107	188	4	84	2.0e-26	86.1	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
2919588895	226	98.64	1	218	2	219	6.5e-45	148.1	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
2919588896	173	82.54	21	173	30	185	4.2e-22	73.1	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2919588897	296	94.25	4	265	9	254	2.8e-38	126.2	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2919588898	346	77.13	1	345	17	360	1.1e-75	249.3	COG0174	Glutamine synthetase	443
2919588900	309	98.38	1	307	6	309	8.4e-126	413.4	COG2066	Glutaminase	309
2919588901	433	96.37	1	429	14	438	0.0e+00	495.6	COG0621	tRNA A37 methylthiotransferase MiaB	437
2919588902	369	96.18	20	361	8	334	2.7e-121	399.1	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
2919588903	160	77.27	3	160	34	152	5.3e-40	131	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
2919588904	375	61.64	27	355	163	432	6.9e-81	266.3	COG1253	Hemolysin or related protein, contains CBS domains	429
2919588905	558	97.31	23	558	9	514	6.1e-127	418.7	COG0815	Apolipoprotein N-acyltransferase	518
2919588906	394	96.72	2	394	10	392	6.5e-113	371.9	COG2807	Cyanate permease	395
2919588907	157	55.04	8	115	32	102	3.3e-14	47	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2919588908	529	96.61	1	500	14	497	0.0e+00	666.2	COG0753	Catalase	496
2919588909	311	98.01	6	302	2	296	5.9e-64	211	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919588910	359	96.59	9	352	10	349	6.6e-91	299	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
2919588911	115	91.06	1	115	9	120	2.9e-30	99.1	COG0818	Diacylglycerol kinase	123
2919588912	509	97.98	1	337	7	345	1.2e-129	426.8	COG1171	Threonine dehydratase	347
2919588915	364	94.74	128	363	8	223	9.6e-56	182.6	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919588916	141	93.98	4	126	5	129	7.9e-17	55.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919588917	899	99.53	8	893	4	853	0.0e+00	935.9	COG0249	DNA mismatch repair ATPase MutS	843
2919588918	764	95.48	2	439	11	432	0.0e+00	567.2	COG0281	Malic enzyme	432
2919588918	764	98.17	441	763	2	322	1.2e-107	353.9	COG0280	Phosphotransacetylase	327
2919588920	825	93.8	4	824	54	870	0.0e+00	764.8	COG1643	HrpA-like RNA helicase	845
2919588921	212	96.43	1	211	5	220	3.2e-63	205.7	COG0283	Cytidylate kinase	222
2919588922	453	97.91	8	447	9	429	1.3e-130	430.2	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
2919588923	128	97.67	1	128	1	126	1.8e-23	77.6	COG4530	Uncharacterized protein	129
2919588926	139	68.48	12	139	52	164	7.7e-19	62.5	COG4731	Uncharacterized conserved protein, DUF2147 family	162
2919588927	893	98.87	1	893	8	879	0.0e+00	1088.7	COG0013	Alanyl-tRNA synthetase	879
2919588928	138	93.6	1	131	4	120	1.7e-26	87.1	COG3686	Uncharacterized conserved protein, MAPEG superfamily	125
2919588929	363	98.97	13	295	4	291	0.0e+00	430.5	COG0468	RecA/RadA recombinase	279
2919588930	894	79.19	303	720	81	392	1.5e-60	200.4	COG0642	Signal transduction histidine kinase	336
2919588931	355	96.14	2	355	4	352	5.9e-110	362.1	COG1377	Flagellar biosynthesis protein FlhB	363
2919588932	254	92.25	1	253	10	247	1.6e-58	192.5	COG1684	Flagellar biosynthesis protein FliR	258
2919588933	88	95.51	1	87	1	85	1.7e-28	93.1	COG1987	Flagellar biosynthesis protein FliQ	89
2919588934	103	78.3	1	103	24	106	4.3e-22	73.1	COG1677	Flagellar hook-basal body complex protein FliE	105
2919588935	135	100	1	135	1	138	1.2e-45	149.5	COG1558	Flagellar basal body rod protein FlgC	137
2919588936	134	93.33	7	134	8	133	1.4e-25	84.4	COG1815	Flagellar basal body rod protein FlgB	133
2919588938	424	35.77	280	422	57	193	5.9e-36	29	COG0477	MFS family permease	338
2919588938	424	77.28	10	284	2	297	5.9e-36	96.1	COG0477	MFS family permease	338
2919588939	390	100	1	390	1	353	1.8e-112	370	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2919588941	424	98.21	1	361	2	330	5.4e-95	312.8	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919588942	294	94.96	33	294	10	254	6.5e-84	275.7	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2919588943	264	98.01	1	260	3	248	9.7e-97	317.7	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2919588945	426	98.36	1	426	6	425	0.0e+00	653	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
2919588946	543	89.26	9	514	49	505	1.5e-130	430.7	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
2919588947	295	92.98	53	290	12	223	1.3e-44	145.8	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919588948	127	24.84	5	127	6	121	9.1e-16	52.1	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2919588949	430	99.06	3	429	4	426	0.0e+00	551.5	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
2919588950	777	64.71	223	770	211	639	3.3e-113	373.2	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919588951	261	93.55	13	254	5	236	6.0e-73	239.7	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
2919588954	404	96.08	1	399	16	407	0.0e+00	454.1	COG0538	Isocitrate dehydrogenase	407
2919588955	265	97.68	3	260	3	255	7.3e-81	265.7	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2919588956	181	96.09	4	180	7	178	1.5e-62	204.5	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
2919588957	44	100	1	44	1	44	3.7e-26	85.5	COG0230	Ribosomal protein L34	44
2919588958	176	91.53	1	128	4	111	1.7e-21	70.7	COG0594	RNase P protein component	117
2919588959	614	93.97	276	611	2	297	1.3e-105	347.7	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
2919588960	217	96.5	18	216	6	198	5.8e-61	199.7	COG0218	GTP-binding protein EngB required for normal cell division	200
2919588961	127	86.29	1	125	11	117	2.3e-21	70.8	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
2919588962	635	93.51	2	631	26	645	0.0e+00	545.5	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919588963	491	99.34	27	478	3	452	0.0e+00	446	COG2031	Short chain fatty acids transporter	446
2919588964	651	95.02	1	645	11	640	0.0e+00	616.2	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919588965	179	90.53	6	179	7	178	5.4e-48	157.7	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2919588966	381	86	2	262	31	288	8.1e-48	157.3	COG2342	Endo alpha-1,4 polygalactosaminidase, GH114 family (was erroneously annotated as Cys-tRNA synthetase)	300
2919588968	876	98.63	5	864	1	794	0.0e+00	1150.4	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2919588969	258	95.19	1	257	4	260	2.3e-32	106.5	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
2919588972	297	99.25	25	296	2	264	8.5e-103	337.4	COG0548	Acetylglutamate kinase	265
2919588973	247	96.54	18	232	5	227	5.3e-33	109.1	COG1011	FMN phosphatase YigB, HAD superfamily	229
2919588974	136	93.38	2	134	8	134	6.1e-48	156.4	COG3824	Predicted Zn-dependent protease, minimal metalloprotease (MMP)-like domain	136
2919588977	336	41.16	66	335	165	369	2.2e-11	35.4	COG2319	WD40 repeat	466
2919588978	220	92.04	1	216	8	215	1.3e-36	120.5	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
2919588979	142	90.98	18	139	7	127	9.5e-19	61.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919588982	185	91.28	10	183	8	164	7.2e-25	82.1	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2919588983	410	96.86	152	405	3	249	1.8e-61	201.5	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
2919588984	437	95.1	2	414	11	398	0.0e+00	436.1	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
2919588985	428	91.78	2	420	35	425	3.9e-90	297	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
2919588986	166	100	1	160	1	156	1.3e-37	123.7	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
2919588987	126	92.17	12	124	3	108	5.2e-40	130.1	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
2919588988	200	86.43	10	200	3	174	1.4e-38	127.1	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
2919588989	432	99.28	16	432	3	416	0.0e+00	538.3	COG0014	Gamma-glutamyl phosphate reductase	417
2919588990	373	99.19	3	371	3	369	5.7e-130	428	COG0263	Glutamate 5-kinase	369
2919588991	345	92.01	1	342	2	335	0.0e+00	447.1	COG0536	GTPase involved in cell partioning and DNA repair	369
2919588992	208	96.26	2	190	6	185	6.9e-24	79.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2919588993	88	98.85	1	86	1	86	5.7e-44	142.3	COG0211	Ribosomal protein L27	87
2919588994	110	99.03	1	103	1	102	2.6e-40	131.5	COG0261	Ribosomal protein L21	103
2919588995	514	91.43	21	496	7	497	2.5e-89	294.7	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
2919588997	339	89.42	47	339	30	291	3.1e-81	267.1	COG3176	Putative hemolysin	292
2919588998	289	66.98	1	289	99	313	7.7e-25	80.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919588999	354	91.79	1	313	29	341	1.0e-112	371	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
2919589000	230	97.67	2	222	2	211	1.9e-38	126.7	COG0625	Glutathione S-transferase	211
2919589001	264	97.8	1	263	4	270	4.8e-91	299.2	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
2919589002	622	81.57	2	516	32	478	9.7e-88	289.2	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
2919589005	512	99.19	14	508	1	488	0.0e+00	620.8	COG0606	Predicted ATPase with chaperone activity	490
2919589006	86	48.54	21	85	16	65	4.1e-04	14.3	COG5591	Uncharacterized protein	103
2919589008	601	66.5	25	586	3	391	0.0e+00	464.8	COG2812	DNA polymerase III, gamma/tau subunits	515
2919589009	107	97.14	1	104	4	105	5.5e-35	114	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
2919589010	637	87.06	33	498	50	392	3.0e-52	172.3	COG0642	Signal transduction histidine kinase	336
2919589010	637	92.48	511	637	8	130	4.2e-20	65.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919589011	539	97.92	7	535	10	527	0.0e+00	750.6	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
2919589012	201	97.47	4	201	5	197	3.1e-71	233.1	COG0353	Recombinational DNA repair protein RecR	198
2919589013	169	42.94	21	160	25	164	1.9e-08	28.3	COG2203	GAF domain	175
2919589014	172	99.41	1	167	1	168	1.1e-63	208.1	COG0242	Peptide deformylase	168
2919589015	310	99.35	1	306	2	307	2.4e-102	336.7	COG0223	Methionyl-tRNA formyltransferase	307
2919589016	261	92.51	1	259	1	247	1.1e-77	255.2	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
2919589017	386	95.93	2	384	15	415	9.7e-98	322.1	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2919589018	262	93.1	5	256	3	245	3.6e-86	282.8	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
2919589019	486	87.93	16	284	27	281	1.1e-27	91.6	COG1398	Fatty-acid desaturase	289
2919589020	125	77.12	2	112	18	108	2.7e-19	64	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2919589022	807	5.98	1	54	268	306	0.0e+00	1.8	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
2919589022	807	99.85	144	806	2	652	0.0e+00	662	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
2919589023	360	98.81	1	343	4	336	5.0e-127	418.3	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
2919589024	123	99.15	1	118	1	117	2.9e-54	176.6	COG0292	Ribosomal protein L20	118
2919589025	67	98.46	1	65	1	64	1.5e-28	93.4	COG0291	Ribosomal protein L35	65
2919589026	377	99.02	5	343	3	407	3.9e-32	102.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919589027	777	93.81	65	752	40	645	0.0e+00	459.4	COG3408	Glycogen debranching enzyme (alpha-1,6-glucosidase)	641
2919589028	285	56.27	9	275	51	207	6.3e-04	14.5	COG0500	SAM-dependent methyltransferase	257
2919589029	173	95.45	2	173	6	173	3.0e-74	242.7	COG0290	Translation initiation factor IF-3	176
2919589030	405	12.47	17	111	325	375	1.9e-41	6.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919589030	405	76.53	96	403	93	405	1.9e-41	130.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919589031	263	89.15	6	263	21	283	2.0e-22	71.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919589032	94	89.41	10	94	10	85	6.1e-32	104.1	COG5568	Uncharacterized protein	85
2919589033	142	87.67	1	139	18	145	1.7e-32	106.6	COG0071	Molecular chaperone IbpA, HSP20 family	146
2919589036	230	97.22	19	222	1	210	7.7e-58	190.2	COG0811	Biopolymer transport protein ExbB/TolQ	216
2919589037	168	89.93	3	144	12	136	9.9e-43	139.7	COG0848	Biopolymer transport protein ExbD	137
2919589038	344	51.46	15	154	6	146	3.5e-20	6.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2919589038	344	74.09	135	343	71	273	3.5e-20	64.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2919589040	439	51.96	20	266	17	215	4.2e-21	39	COG0477	MFS family permease	338
2919589040	439	53	226	436	8	210	4.2e-21	33.4	COG0477	MFS family permease	338
2919589042	81	80	2	81	16	91	7.9e-20	65.6	COG3514	Uncharacterized conserved protein, DUF4415 family	93
2919589043	155	98	4	153	3	149	6.5e-53	173	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
2919589044	59	10.04	3	57	366	411	8.8e-04	12.3	COG1823	L-cystine uptake protein TcyP, sodium:dicarboxylate symporter family	458
2919589045	365	77.46	87	349	50	238	3.5e-39	128.7	COG2114	Adenylate cyclase, class 3	227
2919589046	279	92.91	1	278	7	268	1.7e-76	251.1	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2919589047	517	95.08	304	504	8	181	5.3e-53	173.3	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919589048	732	95.65	58	728	9	690	0.0e+00	694.1	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2919589049	280	85.35	18	226	9	177	1.6e-24	80.9	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2919589050	362	84.02	5	348	16	341	1.1e-47	155.8	COG4763	Uncharacterized membrane protein YcfT	388
2919589052	276	68.18	25	264	74	283	1.4e-18	61.4	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
2919589054	630	99.08	129	586	2	431	0.0e+00	710.5	COG0422	Thiamine biosynthesis protein ThiC	432
2919589056	440	99.48	3	440	3	388	3.8e-23	67.6	COG1344	Flagellin and related hook-associated protein FlgL	360
2919589057	440	23.97	3	108	8	100	1.7e-21	42.3	COG1344	Flagellin and related hook-associated protein FlgL	360
2919589057	440	25.26	321	440	291	388	1.7e-21	32.8	COG1344	Flagellin and related hook-associated protein FlgL	360
2919589057	440	37.11	224	359	67	210	1.7e-21	14.5	COG1344	Flagellin and related hook-associated protein FlgL	360
2919589058	135	91.22	1	135	3	137	2.2e-15	50.8	COG5443	Flagellar biosynthesis regulator FlbT	148
2919589059	123	89.57	2	118	13	115	3.8e-14	47.1	COG5442	Flagellar biosynthesis regulator FlaF	115
2919589063	171	93.55	1	170	5	178	1.5e-47	155.8	COG4186	Calcineurin-like phosphoesterase superfamily protein	186
2919589067	455	92.56	52	437	28	388	1.1e-119	393.8	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
2919589068	2472	14.2	2056	2146	148	194	4.3e-72	4.7	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2919589068	2472	82.72	2343	2425	8	74	2.3e-05	17.7	COG0236	Acyl carrier protein	80
2919589068	2472	96.8	1	1438	6	1154	0.0e+00	967.8	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2919589068	2472	97.89	1725	2050	8	331	4.3e-72	237.2	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2919589069	439	99.52	1	419	2	417	0.0e+00	535.3	COG1004	UDP-glucose 6-dehydrogenase	414
2919589073	190	94.29	16	157	6	137	1.4e-47	154.8	COG1832	Predicted CoA-binding protein	140
2919589074	154	95.04	11	151	5	138	1.4e-30	100	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2919589075	153	97.3	1	149	1	144	6.5e-64	208.6	COG0102	Ribosomal protein L13	148
2919589076	160	97.74	28	160	4	133	3.5e-56	183.4	COG0103	Ribosomal protein S9	130
2919589078	316	95.99	8	316	3	337	4.7e-75	243.2	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
2919589080	179	93.24	1	148	4	141	8.8e-52	169.1	COG4957	Predicted transcriptional regulator	148
2919589082	486	51.25	138	406	7	190	9.9e-07	23.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2919589083	1051	49.39	645	1008	159	360	8.4e-10	32.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919589083	1051	79.87	369	651	5	254	3.3e-24	79.4	COG1216	Glycosyltransferase, GT2 family	305
2919589084	199	87.86	19	188	5	185	1.7e-34	113	COG1335	Nicotinamidase-related amidase	205
2919589085	577	98.38	4	553	3	548	0.0e+00	528	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2919589086	247	59.35	1	247	160	397	8.8e-42	136.4	COG0247	Fe-S oxidoreductase	388
2919589087	536	93.7	78	522	30	460	0.0e+00	440.9	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
2919589088	197	49.33	22	197	111	220	7.4e-17	56.4	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
2919589089	286	76.92	29	280	48	307	1.4e-34	114.4	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2919589090	460	99.12	1	453	2	450	0.0e+00	681.6	COG4303	Ethanolamine ammonia-lyase, large subunit	453
2919589091	259	78.23	2	241	64	293	3.5e-73	240.6	COG4302	Ethanolamine ammonia-lyase, small subunit	294
2919589092	576	98.27	1	565	7	574	0.0e+00	710.6	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2919589093	269	57.4	8	262	104	293	2.9e-29	96.1	COG0790	TPR repeat	292
2919589094	264	99.61	1	263	1	258	8.4e-82	268.7	COG0708	Exonuclease III	261
2919589096	440	98.2	2	325	3	330	7.1e-111	364.7	COG0460	Homoserine dehydrogenase	333
2919589097	330	97.3	13	330	3	326	3.0e-124	408.7	COG1494	Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase or related protein	332
2919589098	290	77.99	6	286	63	349	6.1e-33	108.5	COG0457	Tetratricopeptide (TPR) repeat	291
2919589099	365	93.09	9	365	2	351	3.5e-130	428.6	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
2919589100	166	95.73	1	165	4	160	1.9e-69	226.7	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
2919589101	72	95.52	5	72	4	67	2.8e-26	86	COG5481	Uncharacterized protein	67
2919589102	61	96.49	1	57	1	55	2.1e-25	82.9	COG5570	Uncharacterized protein	57
2919589103	643	98.91	54	622	1	546	0.0e+00	649.3	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2919589104	372	92.84	1	361	4	340	4.4e-114	375.7	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2919589106	210	90.28	9	204	4	198	2.2e-32	106.9	COG0778	Nitroreductase	207
2919589107	173	65.29	7	173	81	238	1.1e-36	121.6	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2919589108	102	42.75	5	102	62	117	1.7e-09	32	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2919589109	81	79.76	1	81	18	84	8.6e-19	62.7	COG5508	Uncharacterized protein	84
2919589110	455	99.72	112	455	1	357	4.6e-94	310	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
2919589114	573	97.88	5	569	12	565	0.0e+00	525.7	COG5360	Uncharacterized conserved protein, heparinase superfamily	566
2919589115	532	99.81	7	532	2	515	0.0e+00	728.2	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
2919589116	437	100	1	437	1	444	0.0e+00	657	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
2919589117	353	75.98	14	342	80	370	1.2e-02	9.4	COG0477	MFS family permease	338
2919589118	556	90.82	32	551	38	423	7.0e-63	207.3	COG0840	Methyl-accepting chemotaxis protein	408
2919589119	189	98.31	11	187	2	176	1.0e-82	270.3	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
2919589120	131	92.59	1	129	5	129	1.6e-33	109.8	COG3791	Uncharacterized conserved protein	133
2919589121	371	46.4	28	370	356	697	1.5e-23	72.7	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
2919589122	310	90.1	17	310	7	279	7.6e-118	387.1	COG0408	Coproporphyrinogen III oxidase	303
2919589124	168	97.4	1	153	1	150	6.0e-51	166.7	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
2919589125	639	98.99	24	607	6	591	0.0e+00	468.2	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2919589126	479	94.78	11	472	14	449	9.0e-91	298.7	COG0534	Na+-driven multidrug efflux pump	455
2919589127	192	92.22	10	191	6	171	1.3e-49	162.6	COG0723	Rieske Fe-S protein	177
2919589128	428	98.77	8	399	5	404	0.0e+00	492.1	COG1290	Cytochrome b subunit of the bc complex	381
2919589129	298	89.17	4	284	30	276	3.6e-74	244.1	COG2857	Cytochrome c1	250
2919589130	291	92.4	1	247	17	259	1.9e-73	241.6	COG0005	Purine nucleoside phosphorylase	262
2919589131	195	98.97	1	195	3	195	6.4e-86	281.3	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
2919589133	220	98.53	3	220	3	203	6.3e-71	232.7	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
2919589134	247	98.34	1	242	3	239	3.6e-89	292.4	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
2919589135	258	99.22	1	257	2	256	2.7e-113	371.8	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
2919589136	107	97.92	6	104	1	94	1.4e-31	102.9	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
2919589137	340	99.29	29	315	3	282	5.3e-109	357.8	COG1072	Panthothenate kinase	283
2919589138	179	98.9	2	179	1	180	9.0e-41	134	COG1514	2'-5' RNA ligase	180
2919589139	226	95.02	22	222	9	218	1.0e-38	127.8	COG2755	Lysophospholipase L1 or related esterase	216
2919589140	227	96.93	1	225	6	226	2.0e-102	335.9	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
2919589141	863	99.52	16	863	5	829	0.0e+00	858	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
2919589142	255	94.83	4	255	12	231	9.2e-74	242	COG0670	Integral membrane protein, interacts with FtsH	233
2919589144	250	93.6	1	250	13	246	7.7e-91	297.9	COG3698	Uncharacterized protein YigE, DUF2233 family	250
2919589147	338	97.94	1	338	7	339	0.0e+00	473.2	COG2130	NADPH-dependent curcumin reductase CurA	340
2919589148	187	99.42	2	187	2	171	1.0e-48	160.3	COG0629	Single-stranded DNA-binding protein	167
2919589150	744	97.96	23	738	5	726	5.0e-129	425.8	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
2919589151	355	95.08	155	339	8	181	1.1e-44	146.2	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919589152	908	99.02	7	898	6	810	0.0e+00	1145.9	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
2919589154	352	95.99	1	352	1	335	0.0e+00	468.4	COG4307	Uncharacterized protein	349
2919589155	166	98.11	1	164	3	158	2.9e-53	174.3	COG0669	Phosphopantetheine adenylyltransferase	159
2919589156	183	95.54	29	180	1	150	6.9e-51	166.6	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
2919589158	152	85.99	6	150	2	136	2.9e-51	167.9	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
2919589159	206	96.39	1	200	5	191	2.0e-49	162	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
2919589160	377	97.2	34	332	8	285	7.6e-94	308.1	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2919589161	167	90.34	7	147	5	135	3.5e-43	141	COG3871	General stress protein 26 (function unknown)	145
2919589162	439	90.98	18	436	2	374	8.1e-87	285.8	COG1488	Nicotinic acid phosphoribosyltransferase	405
2919589163	252	98.02	1	251	2	248	2.7e-98	322.7	COG1540	Lactam utilization protein B (function unknown)	252
2919589164	677	95	18	396	15	356	1.6e-72	236.9	COG0628	Predicted PurR-regulated permease PerM	355
2919589165	262	97.3	4	261	7	258	8.6e-70	229.2	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2919589167	481	96.3	7	481	17	459	0.0e+00	490	COG3106	Predicted ATPase, YcjX-like family	467
2919589168	341	83.71	26	341	49	341	8.5e-88	289.2	COG3768	Uncharacterized membrane protein YcjF, UPF0283 family	350
2919589171	183	97.24	4	183	2	177	2.1e-65	214.2	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
2919589172	365	14.7	300	364	279	329	3.5e-35	3.3	COG4294	UV DNA damage repair endonuclease	347
2919589172	365	68.3	32	293	45	281	3.5e-35	110.8	COG4294	UV DNA damage repair endonuclease	347
2919589173	338	95.57	6	314	3	304	6.5e-97	318.6	COG1984	Allophanate hydrolase subunit 2	314
2919589174	243	92.07	8	229	4	212	2.3e-63	207.7	COG2049	Allophanate hydrolase subunit 1	223
2919589175	298	50	112	177	30	81	7.4e-09	9.1	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2919589175	298	67.31	159	231	34	103	7.4e-09	25.9	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2919589179	473	95.72	1	471	16	485	0.0e+00	489.1	COG0380	Trehalose-6-phosphate synthase	486
2919589180	701	97.16	1	694	13	696	0.0e+00	773.1	COG1523	Pullulanase/glycogen debranching enzyme	697
2919589181	600	93.68	1	596	21	613	0.0e+00	510.7	COG0296	1,4-alpha-glucan branching enzyme	628
2919589182	1634	3.78	1285	1315	391	410	0.0e+00	2.4	COG1640	4-alpha-glucanotransferase	520
2919589182	1634	95.27	150	688	6	509	0.0e+00	478.9	COG1640	4-alpha-glucanotransferase	520
2919589182	1634	99.55	706	1633	4	888	0.0e+00	958.6	COG3280	Maltooligosyltrehalose synthase	889
2919589183	1127	46.62	22	311	33	273	6.6e-53	70.7	COG0366	Glycosidase	505
2919589183	1127	61.32	671	1026	3	319	6.6e-53	100.7	COG0366	Glycosidase	505
2919589184	1088	87.8	620	1086	50	452	5.8e-90	296.2	COG3281	Predicted trehalose synthase	438
2919589184	1088	99.81	13	516	1	516	9.2e-126	415.3	COG0366	Glycosidase	505
2919589185	766	16.27	38	149	14	116	0.0e+00	6.8	COG0296	1,4-alpha-glucan branching enzyme	628
2919589185	766	98.42	137	764	9	631	0.0e+00	845.1	COG0296	1,4-alpha-glucan branching enzyme	628
2919589186	565	81.41	77	560	78	423	9.4e-59	193.5	COG0840	Methyl-accepting chemotaxis protein	408
2919589188	511	98.16	34	506	2	481	0.0e+00	499.7	COG0297	Glycogen synthase	487
2919589189	533	98.45	15	506	2	510	0.0e+00	454.9	COG0366	Glycosidase	505
2919589190	842	99.07	35	840	6	750	0.0e+00	883.6	COG0058	Glucan phosphorylase	750
2919589192	309	77.82	82	302	11	210	1.1e-15	51.1	COG0543	NAD(P)H-flavin reductase	252
2919589194	122	35.34	5	122	2	83	4.2e-08	26.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919589195	961	65.46	432	961	214	647	2.7e-103	340.4	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919589196	431	96.11	6	423	14	433	1.9e-110	363.7	COG0612	Predicted Zn-dependent peptidase	438
2919589197	470	99.05	2	463	4	418	0.0e+00	438.2	COG0498	Threonine synthase	411
2919589199	254	88.98	7	252	18	243	2.4e-65	214.5	COG3346	Cytochrome oxidase assembly protein ShyY1	252
2919589200	123	90.48	2	121	12	125	3.3e-47	153.7	COG5349	Uncharacterized conserved protein, DUF983 family	126
2919589201	285	97.65	59	279	4	211	7.7e-70	228.4	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2919589202	203	90.64	1	197	12	195	4.8e-62	203.3	COG3175	Cytochrome c oxidase assembly protein Cox11	195
2919589203	54	15.11	3	50	67	108	1.8e-03	12.2	COG1082	Sugar phosphate isomerase/epimerase	274
2919589204	321	91.53	14	316	20	300	2.9e-110	362.7	COG0109	Polyprenyltransferase (heme O synthase)	304
2919589205	542	90.69	14	540	4	519	0.0e+00	762.4	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2919589206	278	87.01	17	277	12	232	1.2e-69	228.5	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2919589207	283	96.63	18	280	9	266	5.5e-76	249.5	COG1526	Formate dehydrogenase assembly factor FdhD	266
2919589209	1568	10.02	665	732	358	406	0.0e+00	5	COG0069	Glutamate synthase domain 2	485
2919589209	1568	97.04	1239	1568	2	296	4.7e-110	362.3	COG0070	Glutamate synthase domain 3	301
2919589209	1568	99.18	738	1233	3	487	0.0e+00	696.4	COG0069	Glutamate synthase domain 2	485
2919589209	1568	100	35	421	1	372	0.0e+00	502.2	COG0067	Glutamate synthase domain 1	371
2919589210	476	99.13	22	474	2	455	0.0e+00	565.6	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2919589212	466	77.4	67	387	65	338	1.0e-72	239.2	COG2845	Uncharacterized protein	354
2919589213	404	95.39	1	334	13	343	3.5e-105	346.2	COG2951	Membrane-bound lytic murein transglycosylase B	343
2919589214	330	98.18	1	329	1	323	0.0e+00	432.4	COG1087	UDP-glucose 4-epimerase	329
2919589215	287	98.97	1	287	1	287	1.9e-113	372.7	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
2919589217	300	95.96	14	296	5	265	4.1e-86	282.7	COG3741	N-formylglutamate amidohydrolase	272
2919589218	118	24.63	1	118	6	120	1.6e-24	81	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2919589219	96	98.75	2	80	2	80	7.7e-28	90.9	COG0695	Glutaredoxin	80
2919589220	281	96.4	4	278	3	270	1.1e-73	241.9	COG0388	Predicted amidohydrolase	274
2919589221	155	100	1	155	1	142	1.1e-50	164.9	COG5319	Uncharacterized protein	142
2919589222	174	89.02	6	165	16	169	2.2e-34	113.1	COG1495	Disulfide bond formation protein DsbB	170
2919589223	193	97.52	1	164	1	157	5.9e-41	134.2	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
2919589225	230	86.36	1	206	17	187	2.6e-38	126.1	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2919589226	386	50.89	7	290	57	313	5.7e-16	52.4	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2919589227	304	89.34	1	302	7	316	2.4e-70	231.4	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2919589229	187	89	1	186	3	188	4.0e-14	48.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919589230	369	94.1	5	366	20	386	5.2e-51	168.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919589231	403	94.62	41	401	14	382	4.4e-49	161.8	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919589232	1025	99.8	13	1016	1	1012	0.0e+00	902.8	COG0841	Multidrug efflux pump subunit AcrB	1009
2919589233	200	87.22	30	161	16	131	1.4e-15	51.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919589234	174	87.18	26	169	7	142	6.6e-40	130.5	COG1720	tRNA (Thr-GGU) A37 N-methylase	156
2919589235	497	99.58	210	477	1	236	1.2e-60	199	COG0775	Nucleoside phosphorylase	234
2919589236	562	87.29	40	557	53	423	1.7e-60	199.4	COG0840	Methyl-accepting chemotaxis protein	408
2919589237	817	90.6	79	731	13	658	0.0e+00	625.1	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2919589238	227	93.55	23	206	10	183	1.9e-36	119.4	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
2919589239	411	92.33	66	411	14	338	1.4e-104	343.7	COG1566	Multidrug resistance efflux pump	352
2919589240	543	41.78	287	538	2	161	3.3e-45	8.7	COG0477	MFS family permease	338
2919589240	543	72.06	27	291	4	279	3.3e-45	144.4	COG0477	MFS family permease	338
2919589242	396	9.02	4	65	4	37	3.1e-64	6.1	COG1260	Myo-inositol-1-phosphate synthase	362
2919589242	396	70.82	81	391	97	363	3.1e-64	204.2	COG1260	Myo-inositol-1-phosphate synthase	362
2919589243	305	14.43	214	301	125	152	1.7e-03	2.7	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
2919589243	305	22.16	129	202	29	71	1.7e-03	7.4	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
2919589244	398	64.52	95	372	27	206	6.9e-10	33.4	COG0500	SAM-dependent methyltransferase	257
2919589245	343	96.3	5	338	6	343	8.4e-74	243.2	COG0673	Predicted dehydrogenase	342
2919589246	529	88.03	55	462	41	393	1.9e-22	70.6	COG1944	Ribosomal protein S12 methylthiotransferase accessory factor YcaO	398
2919589247	292	96.04	1	274	9	275	3.6e-28	91.2	COG1082	Sugar phosphate isomerase/epimerase	274
2919589248	412	98.78	1	387	1	404	1.6e-46	153.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919589249	252	87.4	1	247	12	226	4.9e-23	75.9	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
2919589250	212	38.61	29	205	62	139	3.0e-04	12.5	COG1573	Uracil-DNA glycosylase	202
2919589251	355	95.99	33	344	9	319	2.5e-44	146	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2919589252	419	82.23	9	416	69	392	1.8e-67	222.8	COG0642	Signal transduction histidine kinase	336
2919589253	835	8.76	9	79	5	68	0.0e+00	19.9	COG2217	Cation transport ATPase	713
2919589253	835	99.18	75	820	3	727	0.0e+00	846.3	COG2217	Cation transport ATPase	713
2919589254	146	96.97	9	127	2	129	1.8e-32	106.7	COG0789	DNA-binding transcriptional regulator, MerR family	124
2919589255	390	97.71	1	389	5	388	0.0e+00	437.9	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2919589256	462	91.99	23	461	39	486	2.4e-123	407	COG0260	Leucyl aminopeptidase	485
2919589257	285	78.85	23	277	51	255	8.2e-51	167.3	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2919589258	320	92.83	17	320	19	316	7.1e-53	174.1	COG2064	Pilus assembly protein TadC	320
2919589259	323	98.71	6	323	5	309	1.6e-97	320.5	COG4965	Flp pilus assembly protein TadB	309
2919589260	477	97.51	70	430	5	357	0.0e+00	537.4	COG4962	Pilus assembly protein, ATPase of CpaF family	355
2919589261	418	94.63	11	414	10	379	3.1e-95	313.2	COG4963	Flp pilus assembly protein, ATPase CpaE	366
2919589262	245	94.64	1	240	2	213	1.2e-36	120.5	COG5461	Type IV pilus biogenesis protein CpaD/CtpE	224
2919589263	493	94.06	17	493	28	486	3.8e-116	382.7	COG4964	Flp pilus assembly protein, secretin CpaC	455
2919589264	266	85.14	1	263	1	235	3.4e-70	230.7	COG3745	Flp pilus assembly protein CpaB	276
2919589265	172	95.24	4	170	7	166	6.5e-43	140.6	COG4960	Flp pilus assembly protein, protease CpaA	168
2919589266	55	93.1	1	55	1	54	1.8e-24	79.8	COG3847	Flp pilus assembly protein, pilin Flp	58
2919589267	162	14.34	3	134	40	109	1.1e-12	41.6	COG4964	Flp pilus assembly protein, secretin CpaC	455
2919589268	211	56.63	9	178	12	122	2.7e-17	56.8	COG4961	Flp pilus assembly protein TadG	185
2919589269	219	86.73	4	205	2	171	1.3e-21	71.7	COG4961	Flp pilus assembly protein TadG	185
2919589271	500	96.86	20	492	11	473	7.2e-108	355.5	COG1109	Phosphomannomutase	464
2919589272	664	91.06	199	659	37	423	2.8e-53	176.2	COG0840	Methyl-accepting chemotaxis protein	408
2919589273	229	96.77	5	97	4	93	3.3e-26	85.1	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
2919589274	202	97.88	1	187	2	186	1.8e-65	214.3	COG0193	Peptidyl-tRNA hydrolase	190
2919589275	148	95.77	2	141	5	140	5.3e-25	82.2	COG5573	Predicted nucleic acid-binding protein, contains PIN domain	142
2919589276	365	99.73	1	365	1	371	0.0e+00	484.9	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
2919589277	329	86.79	162	327	15	152	8.4e-72	127.8	COG2030	Acyl dehydratase	159
2919589277	329	89.94	1	149	14	156	8.4e-72	109.1	COG2030	Acyl dehydratase	159
2919589280	77	97.26	1	72	1	71	1.1e-32	106.1	COG3655	DNA-binding transcriptional regulator, XRE family	73
2919589282	365	96.82	6	359	4	338	4.5e-123	404.7	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
2919589283	661	16.42	22	190	26	178	0.0e+00	15.6	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2919589283	661	34.01	243	661	403	719	0.0e+00	426.9	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2919589285	687	99.53	41	685	3	640	0.0e+00	775.8	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
2919589287	909	95.31	579	908	6	310	3.8e-85	279.4	COG1754	Uncharacterized C-terminal domain of topoisomerase IA	298
2919589287	909	97.57	1	585	1	561	0.0e+00	661.4	COG0550	DNA topoisomerase IA	570
2919589288	265	87.89	5	265	4	257	3.1e-62	204.3	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2919589289	293	17.65	19	74	23	61	2.1e-51	5.9	COG4117	Thiosulfate reductase cytochrome b subunit	221
2919589289	293	86.88	78	279	28	219	2.1e-51	164	COG4117	Thiosulfate reductase cytochrome b subunit	221
2919589290	311	97.78	1	309	4	311	3.6e-118	388.4	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
2919589291	438	98.38	6	437	2	425	0.0e+00	467.3	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2919589292	201	97.07	8	198	6	204	4.5e-61	200.5	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
2919589293	397	99.16	3	395	2	357	1.0e-105	347.9	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
2919589294	162	95.74	16	155	3	137	3.7e-41	134.7	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
2919589297	95	98.96	1	95	1	95	2.7e-31	102.2	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
2919589298	493	98.34	1	490	3	475	0.0e+00	601.9	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2919589299	102	13.05	5	99	331	383	1.9e-01	5.2	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2919589300	490	98.76	14	490	5	481	0.0e+00	663.8	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
2919589301	346	91.76	29	323	13	335	1.2e-80	259.4	COG1566	Multidrug resistance efflux pump	352
2919589303	432	59.91	3	429	260	670	1.7e-21	70.3	COG1289	Uncharacterized membrane protein YccC	674
2919589307	211	95.81	8	210	4	209	1.9e-60	198.7	COG0625	Glutathione S-transferase	211
2919589308	181	71.52	1	144	47	164	1.7e-17	58.3	COG4731	Uncharacterized conserved protein, DUF2147 family	162
2919589309	140	98.52	2	136	2	134	1.2e-58	191.1	COG0105	Nucleoside diphosphate kinase	135
2919589311	217	99	4	203	2	199	4.2e-75	246	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
2919589312	352	97.39	3	348	3	338	0.0e+00	453.9	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
2919589313	181	88.14	1	174	12	182	1.2e-30	101.4	COG0558	Phosphatidylglycerophosphate synthase	192
2919589314	375	93.06	1	356	17	351	2.1e-86	284.4	COG0628	Predicted PurR-regulated permease PerM	355
2919589315	233	58.2	1	233	89	340	1.0e-30	100.4	COG0593	Chromosomal replication initiation ATPase DnaA	408
2919589316	803	98.71	90	789	7	696	0.0e+00	936.2	COG0855	Polyphosphate kinase	696
2919589317	513	92.53	21	491	4	461	5.3e-116	382.4	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
2919589318	113	86.57	1	71	6	63	2.0e-06	21.2	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2919589320	777	96.83	1	436	12	439	0.0e+00	554	COG0281	Malic enzyme	432
2919589320	777	99.08	433	759	1	324	5.9e-111	364.7	COG0280	Phosphotransacetylase	327
2919589321	202	77.89	3	166	42	189	1.9e-43	143	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2919589324	290	81.47	1	275	3	257	1.6e-38	126.8	COG1216	Glycosyltransferase, GT2 family	305
2919589326	604	99.49	4	600	1	583	0.0e+00	744.7	COG0173	Aspartyl-tRNA synthetase	585
2919589328	385	99.45	4	368	1	360	2.7e-112	369.8	COG0349	Ribonuclease D	361
2919589330	156	96.15	2	156	3	152	1.8e-58	191	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2919589331	734	8.46	186	258	5	67	1.2e-106	19.7	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919589331	734	17.05	22	189	454	580	1.2e-106	79.2	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919589331	734	33.69	488	733	494	744	1.2e-106	188.8	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919589331	734	44.7	259	588	109	441	1.2e-106	86.8	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919589332	600	81.63	2	600	143	773	0.0e+00	562.9	COG4993	Glucose dehydrogenase	773
2919589333	202	56.1	52	191	54	145	5.8e-11	36.8	COG2010	Cytochrome c, mono- and diheme variants	150
2919589334	284	89.75	1	273	7	260	9.1e-19	62.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2919589335	158	96.27	2	158	2	156	1.9e-55	181.2	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
2919589336	123	98.35	1	121	1	119	7.7e-36	117.4	COG1539	Dihydroneopterin aldolase	121
2919589337	279	95.68	12	279	6	271	2.8e-93	306.4	COG0294	Dihydropteroate synthase	274
2919589340	381	92.74	7	344	24	355	5.8e-58	190.8	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2919589341	361	92.56	13	254	10	233	5.2e-63	206.8	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
2919589342	299	90.11	1	294	4	249	6.4e-28	91.9	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2919589344	234	98.28	2	228	2	229	1.9e-66	217.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919589345	538	81.73	149	526	67	388	1.2e-54	181	COG0642	Signal transduction histidine kinase	336
2919589347	264	84.41	1	252	5	226	6.8e-39	128	COG2218	Formylmethanofuran dehydrogenase subunit C	264
2919589348	312	99.66	4	306	2	297	9.7e-90	295.2	COG2037	Formylmethanofuran:tetrahydromethanopterin formyltransferase	297
2919589349	547	96.7	1	542	5	560	4.3e-118	389	COG1229	Formylmethanofuran dehydrogenase subunit A	575
2919589350	357	21.21	4	115	64	154	1.3e-14	20.9	COG1029	Formylmethanofuran dehydrogenase subunit B	429
2919589350	357	30.54	163	355	263	393	1.3e-14	24.5	COG1029	Formylmethanofuran dehydrogenase subunit B	429
2919589351	335	99.04	26	334	2	310	6.8e-78	256.2	COG1907	Predicted archaeal sugar kinase	312
2919589354	402	94.1	2	386	14	380	1.2e-26	87.7	COG2232	Predicted ATP-dependent carboligase, ATP-grasp superfamily	389
2919589355	324	99.04	8	324	2	312	3.0e-87	287.3	COG3252	Methenyltetrahydromethanopterin cyclohydrolase	314
2919589356	307	72.7	44	293	77	305	4.7e-46	151.3	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2919589357	280	95.86	2	273	4	281	1.7e-26	87.5	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
2919589358	170	95.88	5	170	2	164	4.2e-64	210.1	COG1795	Formaldehyde-activating enzyme nesessary for methanogenesis	170
2919589359	233	94.78	5	230	2	219	1.5e-31	103.7	COG1411	Uncharacterized protein related to proFAR isomerase (HisA)	229
2919589360	352	97.58	9	350	5	326	4.4e-61	201.3	COG1548	Uncharacterized protein, hydantoinase/oxoprolinase family	330
2919589362	143	95.62	4	139	2	132	9.4e-21	68.8	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2919589363	251	70.29	1	232	4	223	5.3e-59	194.7	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2919589364	640	87.6	61	636	59	482	3.2e-58	192.3	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2919589365	401	84.73	16	392	34	377	1.5e-52	173	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
2919589366	402	94.7	73	397	14	263	1.2e-49	162.2	COG1237	Metal-dependent hydrolase, beta-lactamase superfamily II	259
2919589367	469	86.8	260	467	7	177	9.9e-75	45.8	COG2059	Chromate transport protein ChrA	195
2919589367	469	88.83	22	234	6	180	9.9e-75	204	COG2059	Chromate transport protein ChrA	195
2919589368	486	95.61	222	486	7	224	3.8e-51	167.5	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919589369	148	66.67	62	129	8	53	1.6e-16	22.8	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2919589369	148	84.06	1	65	1	58	1.6e-16	30	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2919589370	329	20.35	242	327	94	175	2.1e-51	52.8	COG3391	DNA-binding beta-propeller fold protein YncE	381
2919589370	329	26.3	144	247	121	226	2.1e-51	72	COG3391	DNA-binding beta-propeller fold protein YncE	381
2919589370	329	37.47	33	181	50	200	2.1e-51	67.8	COG3391	DNA-binding beta-propeller fold protein YncE	381
2919589371	176	72.6	28	142	3	108	1.5e-04	14.6	COG3427	Carbon monoxide dehydrogenase subunit G	146
2919589372	196	90	3	181	15	194	3.6e-12	40.7	COG2457	Uncharacterized protein	199
2919589373	526	74.1	243	440	72	277	2.4e-14	42.6	COG0294	Dihydropteroate synthase	274
2919589374	196	65.09	6	191	3	140	2.0e-23	77	COG2054	Uncharacterized archaeal kinase related to aspartokinase	212
2919589375	248	36.6	136	240	137	222	6.4e-24	51.8	COG1891	Uncharacterized protein, UPF0264 family	235
2919589375	248	37.02	20	123	2	88	6.4e-24	28.2	COG1891	Uncharacterized protein, UPF0264 family	235
2919589377	407	21.86	62	216	64	143	6.0e-10	24.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919589377	407	26.78	259	385	253	350	6.0e-10	7.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919589378	328	25.81	221	328	78	181	2.3e-55	59	COG3391	DNA-binding beta-propeller fold protein YncE	381
2919589378	328	52.85	24	227	47	259	2.3e-55	129.9	COG3391	DNA-binding beta-propeller fold protein YncE	381
2919589381	254	73.2	7	250	4	227	2.2e-73	241.8	COG1131	ABC-type multidrug transport system, ATPase component	293
2919589382	296	75.43	37	278	59	279	3.2e-17	57	COG0842	ABC-type multidrug transport system, permease component	286
2919589384	819	97.36	2	819	13	786	1.6e-34	111.6	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2919589386	509	98.67	275	509	4	225	7.5e-78	255.1	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2919589387	407	96.09	11	381	12	404	4.9e-40	132.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919589388	160	76.19	3	160	41	184	6.5e-14	46.6	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2919589389	190	66.27	31	188	46	210	1.1e-37	122.2	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2919589390	757	96.13	13	477	10	456	2.5e-90	297.5	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2919589391	400	90.15	5	400	33	398	9.8e-65	213.3	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
2919589392	353	91.79	35	346	2	247	8.1e-35	113.8	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2919589394	68	13.59	1	66	93	148	5.0e-03	10.4	COG0004	Ammonia channel protein AmtB	409
2919589395	369	97.07	10	352	3	333	2.5e-78	257.4	COG1612	Heme A synthase	323
2919589396	206	88.03	1	202	26	231	1.1e-52	172.9	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
2919589401	1011	89.81	109	911	22	735	0.0e+00	536.2	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
2919589403	162	49.44	93	159	34	77	1.9e-03	12.3	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
2919589404	554	97.49	10	510	1	504	9.5e-105	346.2	COG0366	Glycosidase	505
2919589405	215	93.46	1	215	13	255	5.5e-53	174.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2919589406	815	99.69	8	815	3	641	0.0e+00	929.3	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
2919589407	349	96.82	1	348	6	340	8.0e-109	358.2	COG0709	Selenophosphate synthase	346
2919589409	464	95.19	53	460	12	387	2.3e-125	412.8	COG1921	Seryl-tRNA(Sec) selenium transferase	395
2919589410	219	20.08	1	67	3	55	1.8e-28	55.6	COG1192	Cellulose biosynthesis protein BcsQ	259
2919589410	219	52.27	52	211	111	248	1.8e-28	37.7	COG1192	Cellulose biosynthesis protein BcsQ	259
2919589412	224	97.3	1	220	5	220	7.4e-42	138.3	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2919589413	206	61.29	3	204	44	214	1.0e-06	23.8	COG0500	SAM-dependent methyltransferase	257
2919589415	484	12.21	393	473	158	183	1.1e-02	2.8	COG3295	Uncharacterized protein	213
2919589415	484	12.68	234	306	25	51	1.1e-02	4.2	COG3295	Uncharacterized protein	213
2919589415	484	15.96	1	76	19	52	1.1e-02	3.9	COG3295	Uncharacterized protein	213
2919589416	726	96.98	8	726	10	780	1.4e-75	249.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2919589419	228	67.27	17	159	54	164	1.1e-19	63.5	COG4731	Uncharacterized conserved protein, DUF2147 family	162
2919589420	407	90.84	2	407	29	395	3.4e-80	264.7	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2919589421	162	92.42	9	133	8	129	1.2e-30	100.2	COG2343	Uncharacterized conserved protein, DUF427 family	132
2919589422	249	88.06	1	242	18	253	1.4e-44	146.9	COG1877	Trehalose-6-phosphatase	266
2919589423	333	98.12	1	320	5	318	6.7e-96	315.5	COG0837	Glucokinase	320
2919589424	113	99.1	4	112	2	111	4.2e-21	69.7	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
2919589426	492	49.61	282	490	6	195	2.0e-38	37.2	COG0477	MFS family permease	338
2919589426	492	73.37	33	316	5	285	2.0e-38	94.4	COG0477	MFS family permease	338
2919589428	376	94.63	8	376	14	295	1.6e-87	287.6	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2919589429	307	99.69	1	307	1	317	7.5e-94	309.2	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2919589430	530	92.68	7	520	17	548	8.8e-120	395.2	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2919589431	144	95.04	1	140	6	139	3.6e-36	119	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2919589433	351	93.9	21	335	4	280	9.6e-16	52.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919589435	621	98.5	1	517	3	529	0.0e+00	559.7	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2919589438	312	94.02	27	312	3	285	9.9e-66	216.4	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
2919589439	228	87.61	16	214	25	215	4.6e-32	105.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919589440	352	98.34	46	352	3	299	7.6e-81	265.9	COG0031	Cysteine synthase	300
2919589441	363	98.58	8	363	4	351	5.5e-120	395.3	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2919589442	311	95.14	5	311	11	284	6.7e-100	328.6	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2919589443	258	94.01	1	258	11	261	6.7e-96	315.1	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2919589445	245	98.64	1	221	1	217	1.6e-94	309.7	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
2919589446	219	92.89	1	219	6	214	2.4e-95	312.8	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
2919589449	330	80.6	17	326	60	329	2.2e-31	104	COG0582	Integrase	309
2919589455	118	41.29	3	96	64	127	2.1e-07	25.2	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2919589458	103	18.83	19	100	13	70	1.3e-03	12.4	COG4189	Predicted transcriptional regulator	308
2919589464	208	31.54	18	119	13	53	2.1e-07	26.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2919589465	82	32.31	8	81	13	54	2.6e-08	29.5	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2919589466	258	35	56	89	29	56	1.1e-05	4.2	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2919589466	258	40	106	140	24	55	1.1e-05	12.1	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2919589468	126	81.06	1	110	7	113	4.5e-09	31	COG4570	Holliday junction resolvase RusA (prophage-encoded endonuclease)	132
2919589469	262	8.52	193	259	322	351	2.4e-50	6.2	COG0270	Site-specific DNA-cytosine methylase	328
2919589469	262	50.28	1	227	1	177	2.4e-50	159.4	COG0270	Site-specific DNA-cytosine methylase	328
2919589471	292	76.47	4	150	2	118	1.6e-27	90.7	COG3756	Uncharacterized conserved protein YdaU, DUF1376 family	153
2919589474	276	81.72	4	250	42	260	1.4e-18	60.9	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2919589479	70	46.25	1	62	5	41	4.5e-04	14	COG4691	Plasmid stability protein	80
2919589480	54	7.14	2	19	20	33	9.9e-01	1.8	COG4726	Tfp pilus assembly protein PilX	196
2919589480	54	7.65	24	54	14	28	9.9e-01	5.8	COG4726	Tfp pilus assembly protein PilX	196
2919589483	506	63.86	317	473	56	184	5.9e-16	52.2	COG5362	Phage terminase large subunit	202
2919589483	506	94.43	17	315	7	294	1.0e-39	130.7	COG5410	Uncharacterized protein	305
2919589498	328	46.2	158	282	68	146	1.9e-04	16.5	COG4675	Microcystin-dependent protein  (function unknown)	170
2919589501	704	73.95	207	307	19	106	2.2e-05	18.1	COG2018	Predicted regulator of Ras-like GTPase activity, Roadblock/LC7/MglB family	119
2919589503	388	42.02	139	379	38	137	3.8e-13	43.9	COG3409	Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases	185
2919589503	388	94.08	1	144	7	149	2.7e-38	125.3	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
2919589509	333	83.28	27	324	52	330	3.9e-20	67.2	COG0582	Integrase	309
2919589516	258	62.34	65	256	85	228	1.7e-21	71.6	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
2919589519	147	78.79	3	116	7	110	7.0e-14	46.5	COG4570	Holliday junction resolvase RusA (prophage-encoded endonuclease)	132
2919589524	647	73.51	1	384	36	393	4.0e-67	221.4	COG1061	Superfamily II DNA or RNA helicase	442
2919589529	59	12.82	2	50	341	390	2.0e-04	15.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919589530	41	100	1	41	1	38	2.4e-19	63.6	COG0257	Ribosomal protein L36	38
2919589531	205	34.51	3	199	90	216	4.5e-09	31.4	COG0457	Tetratricopeptide (TPR) repeat	291
2919589532	335	99.32	43	324	2	294	1.0e-39	131.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919589533	479	99.16	1	471	3	476	0.0e+00	560.4	COG0469	Pyruvate kinase	477
2919589534	234	82.5	5	113	5	103	3.0e-27	88.7	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2919589535	145	98.5	1	134	1	131	1.2e-53	175.1	COG3607	Predicted lactoylglutathione lyase	133
2919589536	256	96.06	1	126	5	126	7.2e-61	81.3	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2919589536	256	96.06	131	256	4	125	7.2e-61	117.4	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2919589537	146	87.76	2	140	16	144	8.7e-48	156.1	COG5480	Uncharacterized membrane protein	147
2919589538	443	98.82	15	443	5	421	0.0e+00	456.8	COG2379	Glycerate-2-kinase	422
2919589539	250	90.11	4	249	11	247	4.7e-93	306	COG3931	Predicted N-formylglutamate amidohydrolase	263
2919589540	102	93.27	1	102	5	101	1.6e-50	164.3	COG3492	Uncharacterized protein	104
2919589541	88	89.41	6	88	9	84	3.9e-41	133.2	COG3750	Uncharacterized conserved protein, UPF0335 family	85
2919589542	165	88.72	23	158	10	127	1.2e-25	84.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919589543	259	56.03	120	255	52	130	2.3e-08	28	COG4446	Uncharacterized conserved protein, DUF1499 family	141
2919589544	312	86.92	21	297	13	238	1.2e-40	134.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2919589547	58	98.15	1	54	1	53	2.3e-20	67.1	COG5487	Uncharacterized membrane protein YtjA, UPF0391 family	54
2919589549	266	30.11	69	145	125	180	1.6e-17	28.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919589549	266	32.8	1	80	18	78	1.6e-17	27.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919589551	50	58.11	1	50	26	68	7.2e-12	40.4	COG3729	General stress protein YciG, contains tandem KGG domains	73
2919589553	235	62.38	12	173	63	193	1.1e-09	31.9	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
2919589554	147	63.3	9	146	2	139	1.0e-29	98.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919589556	147	98.63	23	143	3	146	8.3e-17	56.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919589557	212	66.94	7	207	78	239	9.3e-53	174.3	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2919589559	897	99.49	10	889	2	784	0.0e+00	800.6	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
2919589561	502	96.22	23	208	8	185	2.8e-60	196.8	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
2919589562	684	85.39	70	620	74	564	4.6e-106	349	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
2919589563	494	98.5	1	493	3	462	0.0e+00	578.7	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2919589564	626	98.33	30	625	10	598	0.0e+00	597.5	COG1164	Oligoendopeptidase F	598
2919589565	74	42.68	1	70	1	35	1.2e-09	33.2	COG2336	Antitoxin component of the MazEF toxin-antitoxin module	82
2919589566	128	89.39	5	126	7	124	9.5e-33	107.2	COG3654	Prophage maintenance system killer protein	132
2919589567	453	74.22	4	446	54	433	2.6e-79	261.5	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
2919589569	380	100	2	369	1	363	0.0e+00	493.2	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2919589570	149	36.36	4	149	71	202	3.5e-30	100	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2919589571	465	100	1	465	1	470	0.0e+00	723.6	COG1282	NAD/NADP transhydrogenase beta subunit	463
2919589572	326	88.35	30	324	6	278	5.0e-59	194.1	COG3386	Sugar lactone lactonase YvrE	307
2919589573	393	63.75	87	391	99	295	2.7e-21	67.3	COG3386	Sugar lactone lactonase YvrE	307
2919589574	602	96.23	63	578	12	496	0.0e+00	445.3	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
2919589577	482	82.99	23	475	64	390	8.5e-48	158.4	COG0642	Signal transduction histidine kinase	336
2919589578	167	81.33	1	167	16	137	2.6e-33	104.6	COG3753	Uncharacterized conserved protein YidB, DUF937 family	143
2919589579	223	93.59	1	149	3	148	6.6e-48	156.9	COG0328	Ribonuclease HI	154
2919589581	249	98.88	2	249	2	266	7.8e-69	226.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919589582	97	57.63	9	96	16	83	2.1e-12	42	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2919589583	294	98.31	11	294	3	292	4.5e-43	142.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919589584	203	96.89	1	203	1	187	1.9e-59	195.2	COG0066	3-isopropylmalate dehydratase small subunit	191
2919589585	479	99.3	1	473	3	428	0.0e+00	559	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
2919589586	449	97.37	8	429	4	410	0.0e+00	470.6	COG1301	Na+/H+-dicarboxylate symporter	415
2919589587	327	99	1	308	1	298	5.3e-44	145.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919589588	58	69.09	1	51	7	44	2.8e-04	15.3	COG3130	Ribosome modulation factor	55
2919589589	515	98.96	27	513	4	479	3.2e-113	373.6	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2919589590	164	86.47	9	146	15	129	1.6e-19	64.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919589591	689	95.04	1	681	8	659	2.9e-79	260.4	COG1289	Uncharacterized membrane protein YccC	674
2919589593	313	92.9	2	299	14	340	1.1e-84	277.4	COG1566	Multidrug resistance efflux pump	352
2919589594	442	97.49	8	416	2	505	3.8e-56	185.7	COG0366	Glycosidase	505
2919589595	522	90.13	108	257	13	149	3.8e-30	98.2	COG5616	TolB amino-terminal domain (function unknown)	152
2919589596	70	89.86	1	69	1	62	9.8e-16	51.8	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2919589597	295	97.01	2	295	3	294	1.8e-47	157.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919589598	454	93.17	5	329	16	315	1.6e-20	63.3	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
2919589599	283	18.22	224	280	194	236	1.0e-20	8.8	COG3637	Opacity protein and related surface antigens	199
2919589599	283	80.93	2	216	2	192	1.0e-20	61.7	COG3637	Opacity protein and related surface antigens	199
2919589602	392	96.88	19	392	7	379	2.5e-107	353.4	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
2919589603	120	90.84	1	120	9	127	5.8e-45	146.8	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
2919589604	948	20.12	25	169	43	142	0.0e+00	7.8	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2919589604	948	21.13	214	380	246	350	0.0e+00	18.4	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2919589604	948	94.16	449	916	27	494	0.0e+00	708.6	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2919589605	396	99.75	1	396	1	393	0.0e+00	735.8	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2919589608	98	79.45	26	94	14	71	6.4e-23	74.7	COG0690	Preprotein translocase subunit SecE	73
2919589609	181	98.36	5	181	2	181	1.1e-65	215.3	COG0250	Transcription antitermination factor NusG	178
2919589610	149	98.58	2	149	1	139	2.3e-56	184.2	COG0080	Ribosomal protein L11	141
2919589611	232	99.13	1	227	1	228	5.5e-97	318.4	COG0081	Ribosomal protein L1	228
2919589612	542	80.32	29	436	24	423	2.9e-35	116.4	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
2919589613	172	96.02	2	171	6	174	6.5e-51	166.8	COG0244	Ribosomal protein L10	175
2919589614	125	98.4	1	125	3	125	3.4e-49	161.1	COG0222	Ribosomal protein L7/L12	124
2919589615	1375	99.26	1	1361	7	1084	0.0e+00	1519.6	COG0085	DNA-directed RNA polymerase, beta subunit/140 kD subunit	1060
2919589616	1401	4.44	899	954	420	455	0.0e+00	12.2	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2919589616	1401	7.15	1302	1375	688	745	0.0e+00	20.1	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2919589616	1401	98.77	14	858	4	804	0.0e+00	985.8	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2919589617	123	95.35	1	123	7	129	1.3e-61	200.4	COG0048	Ribosomal protein S12	129
2919589618	156	99.32	2	149	2	148	1.1e-65	214.4	COG0049	Ribosomal protein S7	148
2919589619	691	98.22	1	691	7	722	0.0e+00	923	COG0480	Translation elongation factor EF-G, a GTPase	697
2919589620	396	99.75	1	396	1	393	0.0e+00	735.8	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2919589621	102	98.08	1	102	1	102	7.9e-48	155.5	COG0051	Ribosomal protein S10	104
2919589622	230	93.39	1	204	11	222	1.1e-68	225.9	COG0087	Ribosomal protein L3	218
2919589623	206	97.7	1	206	2	213	2.8e-69	227.3	COG0088	Ribosomal protein L4	214
2919589624	98	97.87	7	98	1	92	9.4e-37	120.1	COG0089	Ribosomal protein L23	94
2919589625	278	99.64	1	275	1	274	9.3e-121	396.9	COG0090	Ribosomal protein L2	275
2919589626	92	98.92	1	92	1	92	1.6e-41	134.7	COG0185	Ribosomal protein S19	93
2919589627	128	93.29	4	125	8	146	1.5e-43	142.7	COG0091	Ribosomal protein L22	120
2919589628	248	92.7	12	245	1	216	8.2e-96	314.2	COG0092	Ribosomal protein S3	233
2919589629	137	93.29	1	137	2	140	6.2e-58	189.3	COG0197	Ribosomal protein L16/L10AE	146
2919589630	71	95.59	1	70	1	65	9.1e-26	84.3	COG0255	Ribosomal protein L29	69
2919589631	83	89.66	1	82	7	84	8.1e-36	116.5	COG0186	Ribosomal protein S17	87
2919589632	119	97.56	1	119	4	123	5.2e-58	189	COG0093	Ribosomal protein L14	122
2919589633	105	98.15	1	104	2	107	3.1e-33	108.9	COG0198	Ribosomal protein L24	104
2919589634	188	98.89	10	188	2	179	2.2e-82	269.6	COG0094	Ribosomal protein L5	180
2919589635	101	100	41	101	1	61	4.0e-25	81.6	COG0199	Ribosomal protein S14	61
2919589636	131	99.25	1	131	2	133	1.9e-49	161.5	COG0096	Ribosomal protein S8	132
2919589637	177	98.88	1	177	1	177	1.1e-68	224.9	COG0097	Ribosomal protein L6P/L9E	178
2919589638	120	96.03	1	120	6	126	2.5e-42	138.9	COG0256	Ribosomal protein L18	125
2919589639	195	90.22	1	180	17	182	6.8e-71	231.9	COG0098	Ribosomal protein S5	181
2919589640	63	96.36	6	60	1	53	1.6e-21	70.3	COG1841	Ribosomal protein L30/L7E	55
2919589641	166	99.35	1	152	1	153	1.4e-45	149.7	COG0200	Ribosomal protein L15	152
2919589642	448	96.59	7	437	12	436	0.0e+00	496.8	COG0201	Preprotein translocase subunit SecY	436
2919589643	200	99.46	1	192	1	184	1.2e-67	222.2	COG0563	Adenylate kinase or related kinase	178
2919589644	122	100	1	122	1	121	4.3e-52	170.1	COG0099	Ribosomal protein S13	121
2919589645	129	100	1	129	1	130	1.8e-60	197.5	COG0100	Ribosomal protein S11	129
2919589646	291	75	17	290	23	217	1.8e-32	107.4	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2919589647	339	99.06	10	330	3	318	3.5e-120	395.4	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
2919589648	138	100	1	116	1	116	8.5e-51	165.5	COG0203	Ribosomal protein L17	116
2919589650	620	73.86	15	490	101	391	8.9e-48	157.6	COG0642	Signal transduction histidine kinase	336
2919589651	567	78.93	206	567	80	390	2.8e-65	216	COG0642	Signal transduction histidine kinase	336
2919589652	349	97.44	1	348	4	346	3.4e-94	310.3	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2919589653	765	14.19	1	129	4	110	7.3e-93	46.9	COG0643	Chemotaxis protein histidine kinase CheA	716
2919589653	765	54.91	124	634	333	746	7.3e-93	258.4	COG0643	Chemotaxis protein histidine kinase CheA	716
2919589654	555	88	45	555	51	424	9.6e-81	266.4	COG0840	Methyl-accepting chemotaxis protein	408
2919589655	184	65.45	24	177	15	122	2.6e-15	50.8	COG0835	Chemotaxis signal transduction protein	165
2919589656	508	97.78	27	310	4	267	7.8e-67	219.7	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2919589657	169	87.88	4	156	14	158	4.6e-19	62.9	COG0835	Chemotaxis signal transduction protein	165
2919589658	591	99.64	5	570	2	554	0.0e+00	727.6	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2919589659	180	96.91	16	179	3	159	3.5e-59	193.6	COG0440	Acetolactate synthase, small subunit	163
2919589660	95	98.78	1	92	1	81	3.1e-07	23.4	COG2336	Antitoxin component of the MazEF toxin-antitoxin module	82
2919589661	124	97.3	6	114	3	110	6.8e-25	81.9	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
2919589662	214	98.6	4	211	2	213	8.1e-39	128.2	COG0625	Glutathione S-transferase	211
2919589663	339	98.82	1	337	3	336	0.0e+00	528.7	COG0059	Ketol-acid reductoisomerase	338
2919589664	398	10.74	275	366	203	244	4.8e-03	2.6	COG1672	Predicted ATPase, archaeal AAA+ ATPase superfamily	359
2919589664	398	19.18	35	227	26	100	4.8e-03	5.9	COG1672	Predicted ATPase, archaeal AAA+ ATPase superfamily	359
2919589665	217	71.84	25	180	32	156	3.1e-06	21.6	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2919589666	347	98.74	1	324	4	316	5.2e-103	339.1	COG0180	Tryptophanyl-tRNA synthetase	314
2919589667	254	96.68	27	252	5	208	8.9e-44	143.7	COG0177	Endonuclease III	211
2919589668	65	83.33	6	62	11	65	1.9e-08	28.6	COG1724	Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family	66
2919589670	251	84.31	99	251	24	152	3.6e-11	37.5	COG4978	Bacterial effector-binding domain	153
2919589671	295	98.89	7	288	2	269	6.0e-83	272.9	COG0253	Diaminopimelate epimerase	272
2919589672	406	97.96	1	406	5	436	3.8e-111	366.6	COG0621	tRNA A37 methylthiotransferase MiaB	437
2919589673	229	71.58	3	216	84	292	3.0e-57	188.7	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2919589674	481	85.83	93	477	50	358	5.0e-116	382.2	COG0552	Signal recognition particle GTPase	340
2919589676	209	97.78	16	203	2	177	7.4e-64	209.8	COG2917	Intracellular septation protein A	180
2919589677	203	90	43	190	2	136	4.1e-15	50.6	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2919589678	49	68.66	1	49	10	55	9.4e-07	23.7	COG3114	Heme exporter protein D	67
2919589679	269	81.21	5	246	41	269	2.7e-60	198.6	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
2919589680	222	98.64	2	222	2	219	1.1e-72	238.7	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
2919589681	211	96.17	1	201	2	202	9.4e-66	215.8	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
2919589682	89	96.7	1	89	1	88	2.6e-22	73.5	COG2026	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system	90
2919589683	74	77.5	1	74	9	70	4.9e-13	43.8	COG4710	Predicted DNA-binding protein with an HTH domain	80
2919589684	899	99.66	5	899	2	868	0.0e+00	1303.5	COG1048	Aconitase A	861
2919589686	375	93.06	19	373	12	346	1.2e-57	189.9	COG0628	Predicted PurR-regulated permease PerM	355
2919589688	103	87.65	7	96	3	73	2.1e-18	60.8	COG0236	Acyl carrier protein	80
2919589689	158	85.14	1	131	18	143	2.5e-32	106.2	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2919589690	378	85.99	2	359	3	358	1.0e-44	147.2	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2919589691	427	98.55	11	426	5	412	7.9e-115	378.2	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2919589692	264	97.39	16	258	7	267	1.5e-58	192.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919589693	94	32.7	3	94	42	93	3.7e-08	27.8	COG4991	Uncharacterized conserved protein YraI	155
2919589695	130	83.78	2	111	17	109	6.1e-06	20.5	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
2919589696	341	97.58	2	341	8	330	2.6e-90	297.6	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2919589697	341	92.21	6	316	21	304	8.7e-67	219.8	COG1560	Lauroyl/myristoyl acyltransferase	308
2919589698	251	83.14	10	250	38	254	2.5e-69	227.9	COG5429	Uncharacterized protein	261
2919589699	420	99.22	13	420	3	386	0.0e+00	442.5	COG2309	Leucyl aminopeptidase (aminopeptidase T)	385
2919589700	97	98.96	1	97	1	95	2.7e-32	105.6	COG3553	Uncharacterized protein	96
2919589701	524	99.36	55	516	2	467	1.7e-122	404	COG0277	FAD/FMN-containing dehydrogenase	459
2919589702	232	78.02	15	232	58	270	2.6e-70	231.5	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2919589703	156	77.33	9	153	25	157	2.2e-17	58	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2919589708	554	99.63	1	540	2	534	0.0e+00	506.1	COG1283	Na+/phosphate symporter	533
2919589709	462	79.7	128	462	74	387	1.0e-35	118.3	COG0642	Signal transduction histidine kinase	336
2919589710	222	99.14	1	220	1	230	1.6e-69	228.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919589713	423	99.06	9	423	4	423	2.9e-90	297.4	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
2919589714	317	91.39	172	317	9	146	1.2e-43	78.8	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
2919589714	317	94.04	1	151	5	146	1.2e-43	70.7	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
2919589715	457	60.56	105	338	121	315	1.6e-14	45.7	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
2919589717	82	31.93	3	79	82	134	6.4e-06	20.5	COG1813	Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains	165
2919589720	273	77.62	42	271	56	277	8.5e-45	147.5	COG3001	Fructosamine-3-kinase	286
2919589721	156	97.3	5	154	4	147	2.7e-38	125.8	COG0394	Protein-tyrosine-phosphatase	139
2919589722	367	92.98	147	363	13	224	1.3e-22	73.5	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919589727	252	97.61	3	251	3	247	4.5e-93	305.8	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2919589728	250	94.96	1	250	10	254	8.9e-58	190.3	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2919589729	340	94.63	1	340	12	328	1.6e-39	130.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919589733	470	86.61	20	466	3	403	1.7e-62	206.1	COG0415	Deoxyribodipyrimidine photolyase	461
2919589736	370	95.87	6	365	14	361	0.0e+00	447	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
2919589737	189	80.81	6	164	29	167	7.4e-28	91.4	COG5350	Predicted protein tyrosine phosphatase	172
2919589738	370	95.9	10	369	4	354	1.8e-67	222.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919589746	177	92.22	3	169	3	156	1.6e-55	182	COG3685	Ferritin-like metal-binding protein YciE	167
2919589747	646	79.95	155	511	74	388	4.7e-52	172.1	COG0642	Signal transduction histidine kinase	336
2919589748	460	48.21	35	183	65	185	1.9e-48	69.2	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2919589748	460	71.71	127	285	60	239	1.9e-48	104.2	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2919589749	244	90.86	66	239	11	179	4.4e-46	151.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919589751	452	97.18	23	443	10	388	2.0e-31	103.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919589752	562	93.62	1	555	25	567	0.0e+00	725.1	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2919589753	104	48.46	19	102	3	65	2.8e-10	35.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2919589754	234	90.32	60	232	12	179	6.4e-45	147.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919589759	244	84.75	16	232	4	192	6.3e-46	150.8	COG2091	Phosphopantetheinyl transferase	223
2919589760	442	38.9	256	440	45	193	2.2e-12	3.4	COG0477	MFS family permease	338
2919589760	442	61.88	20	287	8	244	2.2e-12	41.1	COG0477	MFS family permease	338
2919589762	276	74.19	1	271	79	331	7.2e-84	276.6	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2919589763	196	96.39	10	175	3	162	1.5e-61	201.5	COG1329	RNA polymerase-interacting regulator, CarD/CdnL/TRCF family	166
2919589764	112	90.41	1	65	5	70	7.5e-19	61.9	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2919589765	95	83	1	94	7	89	6.7e-28	91.7	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
2919589766	1135	86.54	49	732	3	452	1.9e-22	72.9	COG0513	Superfamily II DNA and RNA helicase	513
2919589769	101	94.81	1	95	1	73	2.0e-29	95.9	COG0227	Ribosomal protein L28	77
2919589770	157	99.35	1	157	2	154	5.4e-83	271.1	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
2919589771	186	82.3	6	184	17	188	4.5e-17	57.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919589772	635	98.06	2	617	13	620	0.0e+00	915.3	COG4547	Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib...	620
2919589773	169	36.27	25	103	50	86	2.6e-03	11.6	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2919589774	327	83.33	21	324	22	296	1.1e-55	183.4	COG0714	MoxR-like ATPase	329
2919589776	94	88.89	6	94	8	87	1.4e-29	96.7	COG0271	Stress-induced morphogen (activity unknown)	90
2919589777	143	55.23	1	141	99	230	7.4e-32	105.2	COG1186	Protein chain release factor B	239
2919589778	251	93.36	11	226	6	216	4.1e-36	118.9	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
2919589779	315	98.61	18	311	2	284	3.6e-75	247.3	COG4976	Predicted methyltransferase, contains TPR repeat	287
2919589780	347	94.05	3	334	17	427	1.7e-52	172.2	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
2919589781	587	96.34	59	570	16	489	4.5e-101	333.3	COG1793	ATP-dependent DNA ligase	444
2919589782	171	47.45	102	170	73	137	7.0e-47	78.2	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
2919589782	171	58.39	19	107	7	86	7.0e-47	74.1	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
2919589783	219	69.43	1	204	6	189	2.3e-33	110	COG0300	Short-chain dehydrogenase	265
2919589784	320	98.01	9	307	3	297	6.4e-70	230.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919589785	52	37.23	1	51	87	137	8.8e-19	62.3	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
2919589786	250	98.91	38	230	2	183	9.1e-45	147.1	COG0431	NAD(P)H-dependent FMN reductase	184
2919589787	118	82.2	1	102	10	106	9.4e-14	46.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2919589788	142	97.44	2	118	3	116	5.1e-37	121.1	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2919589789	354	96.21	1	340	9	338	1.1e-109	361	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
2919589791	148	95.36	2	148	4	147	9.8e-41	133.7	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
2919589792	327	99.08	12	327	1	323	1.1e-110	364.6	COG0523	GTPase, G3E family	323
2919589793	423	10.26	311	398	330	373	5.0e-05	12.9	COG3307	O-antigen ligase	424
2919589793	423	60.37	13	297	17	275	5.0e-05	9.1	COG3307	O-antigen ligase	424
2919589794	1078	40.8	982	1078	49	99	5.0e-06	20.6	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2919589794	1078	55.94	837	990	8	120	1.6e-09	30.7	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2919589794	1078	79.7	422	819	78	391	3.6e-80	265	COG0642	Signal transduction histidine kinase	336
2919589797	443	97.56	9	431	4	403	5.4e-125	411.8	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2919589798	214	97.21	1	214	1	209	1.1e-49	163.8	COG0625	Glutathione S-transferase	211
2919589799	341	89.97	11	333	30	334	1.4e-94	311	COG3367	Uncharacterized conserved protein, NAD-dependent epimerase/dehydratase family	339
2919589800	331	92.76	3	331	11	356	8.1e-57	187.1	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2919589801	113	93.04	2	113	2	108	6.8e-38	123.7	COG5447	Uncharacterized protein	115
2919589803	635	82.23	190	573	65	388	3.0e-74	245.5	COG0642	Signal transduction histidine kinase	336
2919589805	348	96.81	11	344	6	339	8.7e-100	328.7	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
2919589808	529	98.87	1	528	1	525	0.0e+00	480.3	COG3898	Uncharacterized membrane-anchored protein	531
2919589809	766	52.13	179	437	36	255	9.6e-21	9.9	COG4223	Uncharacterized conserved protein	422
2919589809	766	63.74	446	751	153	421	9.6e-21	68.9	COG4223	Uncharacterized conserved protein	422
2919589810	237	96.8	1	236	2	243	1.7e-24	80.5	COG1587	Uroporphyrinogen-III synthase	248
2919589811	294	95.53	1	293	13	311	1.1e-32	107.8	COG2017	Galactose mutarotase or related enzyme	308
2919589814	461	89.23	79	458	34	381	2.2e-34	113.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919589815	1073	99.61	1	1062	1	1026	0.0e+00	1260.2	COG3696	Cu/Ag efflux pump CusA	1027
2919589816	70	98.59	1	70	1	70	1.9e-35	115.6	COG3360	Flavin-binding protein dodecin	71
2919589817	561	91.06	111	556	37	423	6.2e-60	196.8	COG0840	Methyl-accepting chemotaxis protein	408
2919589820	364	84.51	76	357	26	276	4.7e-28	91.5	COG1533	DNA repair photolyase	297
2919589821	176	93.41	10	173	4	173	4.4e-07	23.7	COG1514	2'-5' RNA ligase	180
2919589822	252	81.9	39	250	29	218	7.6e-33	109.1	COG0671	Membrane-associated phospholipid phosphatase	232
2919589823	439	98.86	79	419	3	349	7.3e-76	250	COG0673	Predicted dehydrogenase	342
2919589824	540	99.25	1	534	3	533	0.0e+00	601.6	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2919589825	329	96.92	6	328	6	320	9.1e-96	314.7	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2919589826	239	57.85	8	239	5	192	1.6e-34	113.5	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2919589827	466	30.26	83	167	38	106	2.8e-48	2.1	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919589827	466	95.18	252	465	7	223	2.8e-48	154	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919589828	159	89.47	16	149	7	125	9.5e-20	64.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919589829	485	95.96	19	347	7	315	2.5e-17	52.3	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
2919589830	184	87.79	2	179	19	169	1.9e-16	53	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
2919589831	143	96.5	3	141	5	142	1.2e-35	117	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2919589832	403	99.5	3	403	3	404	0.0e+00	568.8	COG4277	Predicted DNA-binding protein with the Helix-hairpin-helix motif	404
2919589833	496	80.69	279	493	28	190	3.7e-45	147.4	COG1573	Uracil-DNA glycosylase	202
2919589834	58	48.45	1	58	7	53	6.8e-12	39.9	COG1669	Predicted nucleotidyltransferase	97
2919589836	65	78.57	1	62	2	56	1.3e-15	51.3	COG5428	Uncharacterized protein YuzE	69
2919589837	607	71.75	410	593	26	185	1.1e-19	65.6	COG1226	Voltage-gated potassium channel Kch	212
2919589837	607	98.28	1	412	2	402	0.0e+00	584	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
2919589838	386	98.02	77	374	3	299	2.1e-74	244.5	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2919589839	1036	92.66	5	325	11	313	1.0e-70	232.5	COG0258	5'-3' exonuclease	310
2919589839	1036	99.83	416	1036	2	597	0.0e+00	769.3	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
2919589840	697	81.41	179	692	78	423	1.9e-61	202.3	COG0840	Methyl-accepting chemotaxis protein	408
2919589844	451	13.25	386	450	30	62	1.1e-27	6.2	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2919589844	451	75.9	16	290	25	213	1.1e-27	83.8	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2919589845	1123	73.13	434	669	62	257	1.1e-47	155.9	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2919589845	1123	74.85	693	1072	20	397	8.6e-62	203.4	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2919589845	1123	78.25	59	393	88	418	2.9e-17	56.3	COG3858	Spore germination protein YaaH	423
2919589848	896	72.01	665	892	64	256	8.9e-53	173.2	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2919589849	185	83.53	4	185	24	165	1.3e-14	48.7	COG0262	Dihydrofolate reductase	167
2919589850	829	88.72	175	827	6	123	1.6e-15	50	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919589852	815	89.7	72	550	14	466	1.6e-72	238.8	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2919589854	384	90.28	54	383	26	350	9.0e-69	225.5	COG3405	Endo-1,4-beta-D-glucanase Y	360
2919589855	660	22.55	66	359	135	217	5.0e-07	10.7	COG0457	Tetratricopeptide (TPR) repeat	291
2919589855	660	63.86	199	478	30	264	5.0e-07	21.8	COG0457	Tetratricopeptide (TPR) repeat	291
2919589857	933	86.29	319	715	40	404	7.5e-53	173.7	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
2919589859	257	79.22	1	256	4	247	2.9e-80	263.9	COG1054	Predicted sulfurtransferase	308
2919589860	69	90.28	2	69	8	72	1.7e-20	67.5	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
2919589861	479	98.33	7	478	4	474	0.0e+00	548.3	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2919589862	263	98.44	1	253	1	252	8.6e-63	206.5	COG0121	Predicted glutamine amidotransferase	252
2919589863	130	24.63	9	130	8	122	1.8e-15	50.9	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2919589864	104	95.52	1	65	3	66	1.4e-23	76.9	COG0828	Ribosomal protein S21	67
2919589865	404	98.07	1	404	1	407	0.0e+00	515.6	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
2919589866	218	96.74	6	216	2	209	1.6e-32	107.2	COG0625	Glutathione S-transferase	211
2919589867	467	85.03	116	456	56	390	1.8e-49	163.8	COG0642	Signal transduction histidine kinase	336
2919589868	240	98.71	7	237	2	230	1.3e-80	264.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919589869	92	78.64	1	91	10	90	4.8e-21	69.2	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
2919589870	169	95.18	4	169	9	166	1.1e-64	211.3	COG5465	Uncharacterized protein	166
2919589871	274	97.76	9	274	4	265	7.0e-73	239.6	COG0345	Pyrroline-5-carboxylate reductase	266
2919589872	256	58.85	9	254	12	134	1.0e-04	15.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919589873	186	96.69	5	183	6	180	7.3e-46	150.3	COG3038	Cytochrome b561	181
2919589875	319	97.86	1	312	6	325	6.7e-94	308.7	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2919589876	470	99.3	2	468	3	428	0.0e+00	642.1	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
2919589878	480	92.54	27	475	13	322	1.2e-16	55.1	COG0582	Integrase	309
2919589883	81	10.07	11	76	7	48	2.8e-01	4.1	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2919589888	188	77.06	2	172	49	216	4.8e-24	79.3	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919589889	103	55.7	19	84	10	53	2.5e-03	11.7	COG1654	Biotin operon repressor	79
2919589892	261	97.71	26	239	4	216	2.3e-29	96.5	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919589895	265	85.78	20	239	26	212	6.7e-22	72	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919589896	126	50.43	8	125	3	119	1.1e-12	41.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919589897	237	96.33	7	213	7	216	1.8e-14	48	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919589901	246	92.66	11	226	15	216	8.8e-25	81.6	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919589903	386	97.25	141	365	6	217	4.4e-27	88.8	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919589904	237	96.79	7	213	7	217	1.1e-16	55.1	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919589906	243	96.33	5	209	5	214	9.2e-13	42.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919589907	260	88.33	10	256	17	243	6.1e-57	186.5	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2919589908	156	48.35	3	126	122	238	1.7e-10	35.2	COG2202	PAS domain	232
2919589910	143	89.47	1	122	11	129	1.3e-17	58.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919589914	772	64.29	633	765	11	127	7.5e-07	21.9	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2919589914	772	95.87	250	627	12	359	4.6e-27	88.8	COG3852	Signal transduction histidine kinase, nitrogen specific	363
2919589914	772	97.88	1	236	5	235	3.7e-62	203.6	COG3300	MHYT domain, NO-binding membrane sensor	236
2919589921	54	92.86	1	53	4	55	5.5e-24	78.1	COG0401	Uncharacterized membrane protein YqaE, homolog of Blt101, UPF0057 family	56
2919589924	302	93.03	11	294	17	283	8.0e-66	216.1	COG2890	Methylase of polypeptide chain release factors	280
2919589925	361	97.25	2	360	7	359	0.0e+00	502.3	COG0216	Protein chain release factor A	363
2919589926	754	98.54	8	754	5	749	0.0e+00	1005.8	COG3605	Signal transduction protein containing GAF and PtsI domains	756
2919589927	411	99.32	1	409	2	441	0.0e+00	452.4	COG0527	Aspartokinase	447
2919589928	256	97.54	6	256	6	243	1.4e-87	287.2	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2919589929	190	87.15	18	190	23	178	3.7e-41	134.9	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
2919589930	324	100	1	324	1	331	2.1e-88	291.1	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2919589931	337	95.25	6	335	1	301	1.7e-67	221.9	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2919589932	184	96	1	183	4	195	2.8e-22	73.1	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
2919589934	297	88.68	16	211	10	197	2.4e-50	165	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
2919589935	812	99.7	19	810	2	673	0.0e+00	816.5	COG0272	NAD-dependent DNA ligase	667
2919589936	302	67.32	1	221	20	190	1.1e-35	118	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2919589937	733	24.32	637	729	191	270	2.2e-106	8	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2919589937	733	94.34	1	312	6	255	2.7e-56	185.3	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919589937	733	99.7	325	665	2	329	2.2e-106	348.4	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2919589939	402	99.75	1	402	2	394	2.2e-120	396.6	COG0183	Acetyl-CoA acetyltransferase	392
2919589940	597	96.99	20	461	8	394	3.0e-100	330.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919589941	1102	24.14	189	239	5	39	2.8e-01	3.1	COG1730	Prefoldin subunit 5	145
2919589941	1102	29.66	331	384	6	48	2.8e-01	5.8	COG1730	Prefoldin subunit 5	145
2919589941	1102	61.03	762	1054	57	258	1.4e-37	123.3	COG0790	TPR repeat	292
2919589943	355	97.31	16	353	8	332	1.0e-83	275.1	COG2855	Uncharacterized membrane protein YadS	334
2919589944	250	87.45	30	250	6	214	2.1e-50	165.5	COG1407	Metallophosphoesterase superfamily enzyme	235
2919589945	881	97.69	8	881	7	851	0.0e+00	775.6	COG1201	Lhr-like helicase	814
2919589946	320	91.82	7	320	23	314	3.6e-55	182	COG0657	Acetyl esterase/lipase	312
2919589948	454	92.61	2	438	16	441	4.5e-75	246.9	COG0534	Na+-driven multidrug efflux pump	455
2919589951	294	98.95	9	294	1	282	5.7e-87	285.8	COG2301	Citrate lyase beta subunit	283
2919589952	358	98.71	43	353	2	307	1.8e-96	317	COG0167	Dihydroorotate dehydrogenase	310
2919589953	120	94.78	1	113	5	113	4.5e-48	156.4	COG3502	Uncharacterized conserved protein, DUF952 family	115
2919589954	210	98.27	1	210	1	227	9.4e-44	144.2	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
2919589955	368	73.1	15	368	101	388	7.5e-40	132	COG0642	Signal transduction histidine kinase	336
2919589956	326	99.64	42	326	1	280	1.3e-55	183	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
2919589957	287	98.08	18	283	3	257	1.4e-75	248.1	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
2919589958	375	98.49	3	341	3	328	2.0e-109	360.2	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
2919589959	865	94.85	2	864	27	781	0.0e+00	445.8	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
2919589960	362	99.18	5	362	3	364	8.1e-58	190.4	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
2919589961	386	97.81	1	360	3	359	1.6e-61	202.6	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
2919589962	499	91.58	24	497	41	486	0.0e+00	522.9	COG0260	Leucyl aminopeptidase	485
2919589964	564	97.54	19	562	4	557	0.0e+00	465.6	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919589965	314	87.54	14	290	30	282	3.5e-71	233.8	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2919589967	296	98.34	1	296	2	297	5.2e-67	221	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919589968	326	98.7	3	315	2	304	3.7e-125	411.2	COG0492	Thioredoxin reductase	305
2919589969	337	96.96	20	328	3	321	4.4e-55	181	COG3660	Mitochondrial fission protein ELM1	329
2919589971	160	99.34	8	159	1	151	2.8e-58	190.5	COG0782	Transcription elongation factor, GreA/GreB family	151
2919589972	1157	43.9	625	815	1	180	0.0e+00	151.4	COG0458	Carbamoylphosphate synthase large subunit	400
2919589972	1157	47.8	822	1038	190	385	0.0e+00	77.3	COG0458	Carbamoylphosphate synthase large subunit	400
2919589972	1157	99.76	13	484	1	409	0.0e+00	717.4	COG0458	Carbamoylphosphate synthase large subunit	400
2919589974	411	98.92	22	405	3	369	0.0e+00	484.4	COG0505	Carbamoylphosphate synthase small subunit	368
2919589975	154	99.32	1	151	1	147	5.5e-54	176.8	COG1610	Uncharacterized conserved protein YqeY	148
2919589976	636	95.97	2	613	1	572	0.0e+00	502.9	COG0358	DNA primase (bacterial type)	568
2919589977	664	27.27	55	178	8	100	0.0e+00	9.9	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2919589977	664	98.83	307	663	5	341	0.0e+00	434.9	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2919589978	398	80.74	157	396	38	234	2.5e-39	129.5	COG2114	Adenylate cyclase, class 3	227
2919589980	401	98.71	21	398	2	384	7.3e-69	227	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2919589981	70	97.06	1	70	3	68	3.0e-17	56.4	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
2919589982	268	97.71	11	268	4	259	4.3e-110	361.3	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
2919589983	216	95.26	2	211	8	208	8.0e-45	146.7	COG0352	Thiamine monophosphate synthase	211
2919589984	250	94.51	1	249	1	241	1.7e-91	300.1	COG3484	Predicted proteasome-type protease	255
2919589985	275	92.6	1	274	11	323	5.9e-42	137.6	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2919589986	314	98.4	1	314	1	308	1.0e-90	298.7	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2919589987	476	96.31	1	476	8	477	0.0e+00	677.4	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
2919589988	244	96.88	23	244	8	224	5.0e-76	249.2	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
2919589989	286	98.06	17	267	5	308	1.5e-84	278	COG0024	Methionine aminopeptidase	255
2919589990	85	98.39	1	62	1	61	5.7e-24	78	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
2919589991	395	95.17	2	388	3	376	3.0e-70	231.6	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2919589993	139	72.57	21	128	16	97	7.0e-07	23	COG3895	Membrane-bound inhibitor of C-type lysozyme	112
2919589994	607	98.44	5	605	5	573	0.0e+00	627.9	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2919589995	205	94.31	1	205	5	203	1.6e-70	231	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
2919589996	241	96.79	4	221	4	214	1.3e-24	81.1	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919589997	704	90.77	140	701	49	599	0.0e+00	591.2	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
2919590001	546	99.09	1	538	1	545	0.0e+00	634.8	COG0459	Chaperonin GroEL (HSP60 family)	524
2919590002	95	97.92	1	95	1	94	5.1e-43	139.5	COG0234	Co-chaperonin GroES (HSP10)	96
2919590003	334	90.24	8	334	33	328	1.0e-62	206	COG0598	Mg2+ and Co2+ transporter CorA	322
2919590007	702	99.57	1	702	3	690	0.0e+00	819.3	COG0751	Glycyl-tRNA synthetase, beta subunit	691
2919590008	312	94.97	7	311	4	286	0.0e+00	511.7	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
2919590010	285	75.31	6	282	55	295	2.6e-71	234.7	COG0616	Periplasmic serine protease, ClpP class	317
2919590012	257	90.32	6	250	21	244	1.6e-51	168.9	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
2919590014	340	98.78	19	340	4	327	2.4e-98	323.4	COG0142	Geranylgeranyl pyrophosphate synthase	322
2919590015	291	96.55	1	290	2	281	1.5e-63	208.8	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
2919590016	627	31.25	453	603	231	345	8.8e-30	30.6	COG0457	Tetratricopeptide (TPR) repeat	291
2919590016	627	62.5	252	474	127	356	8.8e-30	60.3	COG0457	Tetratricopeptide (TPR) repeat	291
2919590016	627	78.26	25	314	57	344	8.8e-30	24	COG0457	Tetratricopeptide (TPR) repeat	291
2919590017	557	99.75	8	468	2	407	3.7e-121	399.2	COG0644	Dehydrogenase (flavoprotein)	396
2919590018	284	96.53	91	283	5	199	2.4e-59	194.1	COG1573	Uracil-DNA glycosylase	202
2919590019	301	98.65	1	301	1	292	3.2e-112	368.8	COG2321	Predicted metalloprotease	295
2919590020	503	98.3	30	501	3	465	0.0e+00	669.6	COG1027	Aspartate ammonia-lyase	471
2919590021	280	88.93	14	280	27	275	2.9e-97	319.1	COG2998	ABC-type tungstate transport system, permease component	280
2919590022	241	71.57	5	231	6	224	3.1e-48	158.8	COG1131	ABC-type multidrug transport system, ATPase component	293
2919590023	231	97.8	1	225	4	225	9.5e-67	218.8	COG4662	ABC-type tungstate transport system, periplasmic component	227
2919590024	328	71.76	6	127	21	114	2.8e-15	50	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
2919590024	328	87.89	122	324	3	198	6.1e-44	143.8	COG1910	Periplasmic molybdate-binding protein/domain	223
2919590025	417	97.05	9	415	6	400	3.6e-129	424.9	COG0303	Molybdopterin biosynthesis enzyme	404
2919590026	184	98.77	5	165	2	161	2.5e-46	151.9	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
2919590027	663	89.69	447	660	3	202	3.0e-43	141.2	COG1910	Periplasmic molybdate-binding protein/domain	223
2919590027	663	98.77	24	440	3	404	1.7e-121	399.7	COG0303	Molybdopterin biosynthesis enzyme	404
2919590028	367	98.03	5	367	5	403	4.6e-48	154.3	COG0303	Molybdopterin biosynthesis enzyme	404
2919590029	425	24.92	129	249	56	132	5.6e-04	6.7	COG3386	Sugar lactone lactonase YvrE	307
2919590029	425	33.33	34	167	74	176	5.6e-04	6.9	COG3386	Sugar lactone lactonase YvrE	307
2919590029	425	75	305	425	31	132	2.5e-25	82.8	COG3474	Cytochrome c2	135
2919590030	679	50.81	544	669	41	103	1.9e-23	24.8	COG1145	Ferredoxin	99
2919590030	679	54.84	261	344	40	107	1.9e-23	31.2	COG1145	Ferredoxin	99
2919590030	679	70.16	298	585	38	124	1.9e-23	49.5	COG1145	Ferredoxin	99
2919590036	194	64.71	41	193	61	192	1.5e-29	96.9	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
2919590038	980	99.63	26	980	2	808	0.0e+00	597.9	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2919590039	198	75.12	1	191	11	164	3.7e-43	141.4	COG0437	Fe-S-cluster-containing dehydrogenase component	203
2919590040	331	94.5	109	324	3	208	2.8e-50	164.9	COG2864	Cytochrome b subunit of formate dehydrogenase	218
2919590044	388	91.77	14	386	12	368	8.2e-59	193.5	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2919590047	386	97.8	10	370	7	406	1.4e-39	131.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919590048	634	98.91	1	620	1	542	0.0e+00	462.8	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2919590049	357	96.82	4	357	11	406	2.9e-43	143.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919590050	492	95.23	1	471	11	469	3.5e-32	105.8	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2919590051	260	94.07	1	244	9	246	1.5e-70	231.3	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
2919590052	422	95.64	1	421	8	424	0.0e+00	466	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
2919590053	403	96.88	2	381	2	373	0.0e+00	437.7	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
2919590055	489	95.7	7	466	13	457	5.3e-98	322.7	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2919590056	190	89.78	1	190	10	211	2.1e-34	113.6	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
2919590057	366	91.74	1	357	5	337	2.1e-99	327.3	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2919590058	306	99.34	1	295	1	299	1.2e-60	200.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919590060	89	48.7	6	82	13	68	1.1e-04	16.8	COG4467	Regulator of replication initiation timing	114
2919590063	369	85.12	4	369	6	371	2.6e-83	274.1	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
2919590064	717	88.52	404	650	19	234	7.3e-50	164.1	COG2114	Adenylate cyclase, class 3	227
2919590064	717	93.1	1	418	25	402	5.1e-50	160.9	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2919590066	238	97.39	10	238	5	228	8.1e-71	232.1	COG1346	Putative effector of murein hydrolase	230
2919590067	136	33.59	1	54	7	49	2.5e-22	25.1	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
2919590067	136	55.47	57	135	56	126	2.5e-22	46.7	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
2919590068	159	85.14	2	149	21	146	6.4e-25	81.6	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
2919590073	1127	17.89	419	614	720	880	9.7e-34	59.3	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
2919590073	1127	21.67	199	474	167	361	9.7e-34	19	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
2919590073	1127	24.11	25	262	80	296	9.7e-34	33.4	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
2919590074	972	98.8	7	970	2	905	0.0e+00	642.6	COG1743	Adenine-specific DNA methylase, contains a Zn-ribbon domain	875
2919590075	939	98.6	7	793	2	778	0.0e+00	612.1	COG1483	Predicted ATPase, AAA+ superfamily	774
2919590077	232	80.97	10	224	4	186	1.8e-25	83.7	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2919590080	77	61.43	13	74	11	53	4.4e-07	24	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2919590081	114	61.15	2	108	8	92	1.6e-07	25.4	COG3415	Transposase	138
2919590086	2117	20.19	770	936	197	282	1.4e-03	9.2	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
2919590086	2117	40.61	1124	1385	34	206	1.4e-03	8.3	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
2919590086	2117	75.19	1815	1944	29	125	1.3e-07	24.1	COG2852	Very-short-patch-repair endonuclease	129
2919590087	886	21.19	727	875	126	182	5.2e-06	16.3	COG2887	RecB family exonuclease	269
2919590087	886	27.14	582	710	2	74	5.2e-06	1.5	COG2887	RecB family exonuclease	269
2919590088	1118	72.22	9	891	9	840	3.4e-117	384.3	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2919590090	412	96.12	80	407	8	329	1.9e-21	70.9	COG0582	Integrase	309
2919590092	321	97.97	16	292	4	292	7.4e-36	118.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919590093	363	85.12	1	358	25	373	6.8e-63	206.9	COG4645	Uncharacterized protein	410
2919590095	464	82.57	36	455	10	407	1.3e-41	136.8	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2919590096	374	73.4	4	320	33	330	1.2e-12	41.5	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
2919590097	500	97.99	5	468	2	440	3.6e-110	362.9	COG1232	Protoporphyrinogen oxidase	444
2919590100	529	89.22	5	507	49	495	6.5e-96	316.1	COG2939	Carboxypeptidase C (cathepsin A)	498
2919590101	150	99.31	1	148	2	144	2.4e-39	128.9	COG2927	DNA polymerase III, chi subunit	144
2919590102	542	99.25	2	541	2	532	0.0e+00	800.1	COG0504	CTP synthase (UTP-ammonia lyase)	533
2919590103	142	86.02	1	98	1	80	5.4e-25	81.2	COG1314	Preprotein translocase subunit SecG	86
2919590104	238	93.65	1	238	13	248	9.7e-80	261.9	COG0149	Triosephosphate isomerase	251
2919590105	629	96.31	8	401	2	314	3.5e-23	76.9	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2919590106	506	98.07	22	500	6	463	0.0e+00	520.1	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2919590107	557	90.59	25	552	39	423	2.0e-58	192.6	COG0840	Methyl-accepting chemotaxis protein	408
2919590108	209	98.43	6	194	3	190	2.5e-74	243.1	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
2919590109	337	99.12	1	337	3	339	6.2e-129	424.1	COG0547	Anthranilate phosphoribosyltransferase	338
2919590110	276	99.61	15	272	1	253	3.8e-98	321.9	COG0134	Indole-3-glycerol phosphate synthase	254
2919590111	161	98.72	1	158	2	155	6.8e-64	208.6	COG0315	Molybdenum cofactor biosynthesis enzyme	157
2919590112	409	98.28	1	408	5	404	3.7e-130	428.4	COG0303	Molybdopterin biosynthesis enzyme	404
2919590113	240	98.52	1	240	3	202	4.0e-75	246.1	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2919590114	491	49.68	1	343	220	455	8.7e-43	140.8	COG0658	Predicted membrane metal-binding protein	453
2919590115	266	35.37	43	236	11	178	7.1e-09	29.2	COG0658	Predicted membrane metal-binding protein	453
2919590116	475	97.5	1	474	9	476	0.0e+00	502.3	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2919590117	429	99.49	25	428	3	396	0.0e+00	550.9	COG0372	Citrate synthase	390
2919590118	792	88.84	44	790	53	641	1.2e-126	417.4	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919590119	385	98.42	1	381	3	376	4.4e-116	381.9	COG0763	Lipid A disaccharide synthetase	381
2919590120	293	97.85	10	292	5	277	6.3e-67	219.9	COG3494	Uncharacterized conserved protein, DUF1009 family	279
2919590121	266	97.69	1	256	6	259	1.7e-107	352.7	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
2919590122	154	96.62	8	154	4	146	4.4e-49	160.3	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2919590123	736	77.66	250	589	84	389	6.4e-54	178.4	COG0642	Signal transduction histidine kinase	336
2919590124	353	97.04	10	351	3	330	1.0e-113	373.9	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
2919590125	855	98.84	5	855	10	774	0.0e+00	629.2	COG4775	Outer membrane protein assembly factor BamA	766
2919590126	385	98.51	14	379	5	400	4.4e-92	303.6	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
2919590127	523	46.21	270	519	2	178	9.3e-37	26.3	COG0477	MFS family permease	338
2919590127	523	65.01	17	268	3	251	9.3e-37	100.7	COG0477	MFS family permease	338
2919590128	408	95.45	40	406	9	344	2.2e-108	356	COG1566	Multidrug resistance efflux pump	352
2919590129	214	93.3	1	214	11	205	1.7e-27	91.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919590130	392	97.15	2	390	3	377	0.0e+00	442.6	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
2919590131	291	98.18	23	289	2	271	9.8e-52	170.5	COG0575	CDP-diglyceride synthetase	265
2919590132	274	92.46	19	268	20	252	3.3e-96	315.7	COG0020	Undecaprenyl pyrophosphate synthase	245
2919590133	187	96.26	1	187	8	187	1.3e-76	250.5	COG0233	Ribosome recycling factor	187
2919590134	240	97.48	5	240	5	236	3.3e-81	266.5	COG0528	Uridylate kinase	238
2919590135	308	99.33	1	307	1	295	3.3e-109	358.8	COG0264	Translation elongation factor EF-Ts	296
2919590136	356	92.58	1	257	6	242	7.3e-103	337.1	COG0052	Ribosomal protein S2	252
2919590138	991	14.73	779	920	162	208	2.6e-07	3	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2919590138	991	20.06	12	143	12	75	2.6e-07	19.5	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2919590139	257	96.75	11	253	3	240	1.1e-58	192.5	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2919590140	306	89.4	25	306	31	300	3.0e-62	204.6	COG2813	16S rRNA G1207 methylase RsmC	300
2919590141	324	98.32	26	322	4	296	7.1e-112	367.6	COG1159	GTPase Era, involved in 16S rRNA processing	298
2919590142	253	95.76	14	244	5	230	6.8e-67	219.2	COG0571	dsRNA-specific ribonuclease	235
2919590143	264	90.91	16	252	7	166	2.3e-29	94.8	COG0681	Signal peptidase I	166
2919590144	137	96.85	1	131	2	124	1.8e-38	125.8	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
2919590145	255	99.18	6	248	2	242	7.3e-99	324.2	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
2919590147	151	96.43	1	113	3	110	2.8e-39	127.8	COG0360	Ribosomal protein S6	112
2919590148	83	83.54	7	78	14	79	1.4e-31	103.1	COG0238	Ribosomal protein S18	75
2919590150	188	99.32	1	148	1	147	6.0e-52	169.8	COG0359	Ribosomal protein L9	148
2919590151	495	99.77	19	487	1	435	0.0e+00	480.7	COG0305	Replicative DNA helicase	435
2919590153	328	91.76	1	327	30	363	1.5e-99	327.6	COG0787	Alanine racemase	360
2919590154	476	95.83	1	456	1	437	0.0e+00	618	COG1066	Predicted ATP-dependent serine protease	456
2919590155	207	92.31	3	182	2	169	1.0e-43	143.5	COG1286	Uncharacterized membrane protein, required for colicin V production	182
2919590156	496	97.02	25	489	2	457	0.0e+00	641.8	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
2919590157	250	92.54	7	245	3	250	3.9e-49	161.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919590158	135	80	3	131	4	139	8.7e-09	24.9	COG0262	Dihydrofolate reductase	167
2919590159	84	78.57	1	84	2	67	2.5e-13	43.4	COG4118	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor	84
2919590160	140	98.58	2	138	1	139	2.1e-09	32.3	COG1848	Predicted nucleic acid-binding protein, contains PIN domain	140
2919590161	380	96.48	4	372	3	358	2.9e-93	307.1	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
2919590162	308	95.37	62	308	7	253	1.8e-36	120.2	COG0730	Uncharacterized membrane protein YfcA	258
2919590163	661	81.41	176	655	78	423	2.6e-56	185.6	COG0840	Methyl-accepting chemotaxis protein	408
2919590164	449	99.33	1	448	3	444	0.0e+00	538.7	COG1160	Predicted GTPases	444
2919590165	236	97.29	2	219	3	217	8.5e-53	173.2	COG4649	Uncharacterized protein	221
2919590166	202	70.78	1	197	1	155	5.7e-37	121.1	COG4094	Uncharacterized membrane protein	219
2919590175	142	7.11	42	141	340	422	7.1e-05	14.7	COG1196	Chromosome segregation ATPase	1163
2919590176	437	69.68	21	372	31	377	8.6e-25	81.7	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
2919590177	457	66.06	29	376	50	378	2.1e-24	80.4	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
2919590178	263	55.91	7	256	54	209	5.7e-19	63.2	COG0500	SAM-dependent methyltransferase	257
2919590181	39	6.34	1	39	1	39	3.1e-16	53.4	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
2919590182	1353	61.19	493	713	96	259	1.3e-04	14.5	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2919590184	458	67.66	21	282	39	287	8.7e-04	15.2	COG0457	Tetratricopeptide (TPR) repeat	291
2919590187	512	76.28	18	502	92	403	1.1e-36	121.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919590188	466	96.79	1	464	1	452	7.7e-68	223.6	COG4267	Uncharacterized membrane protein	467
2919590189	451	73.49	19	240	39	221	8.7e-28	91.6	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2919590190	305	78	23	294	25	258	8.5e-57	186.8	COG2342	Endo alpha-1,4 polygalactosaminidase, GH114 family (was erroneously annotated as Cys-tRNA synthetase)	300
2919590191	215	94.79	1	213	10	209	4.1e-32	105.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919590193	309	97.76	1	309	6	311	1.5e-50	166.4	COG0679	Predicted permease	311
2919590195	355	92.74	15	355	22	353	8.2e-96	315.3	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
2919590197	187	91.04	1	62	6	66	1.9e-48	68.7	COG1278	Cold shock protein, CspA family	67
2919590197	187	95.52	120	186	2	65	1.9e-48	88.7	COG1278	Cold shock protein, CspA family	67
2919590198	157	31.49	2	153	133	269	1.1e-19	64.6	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2919590199	383	63.03	55	382	2	313	2.0e-101	334.4	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
2919590200	235	98.05	29	232	3	203	1.3e-79	261.1	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
2919590201	141	95.69	18	133	4	114	3.8e-57	185.6	COG3564	Uncharacterized conserved protein, DUF779 family	116
2919590202	506	99.37	19	501	2	477	0.0e+00	594.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2919590203	455	89.11	4	390	36	395	8.3e-69	226.9	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2919590204	422	95.82	20	419	8	374	1.7e-26	86.8	COG0477	MFS family permease	338
2919590205	167	90.28	2	139	11	140	4.4e-21	70	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2919590206	473	52.74	254	465	4	205	8.5e-38	16.3	COG0477	MFS family permease	338
2919590206	473	75.98	2	250	8	298	8.5e-38	114.6	COG0477	MFS family permease	338
2919590208	497	94.5	3	220	12	217	6.0e-109	143.7	COG0516	IMP dehydrogenase/GMP reductase	170
2919590208	497	99.54	265	485	1	217	6.0e-109	217.6	COG0516	IMP dehydrogenase/GMP reductase	170
2919590209	152	97.84	10	148	1	136	1.4e-34	113.4	COG5331	Uncharacterized protein	139
2919590210	316	99.03	1	315	1	306	5.9e-64	210.6	COG1893	Ketopantoate reductase	307
2919590212	369	90.78	28	369	32	356	4.9e-74	244.2	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
2919590214	519	98.99	6	200	2	197	2.9e-69	226.9	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2919590214	519	100	201	519	1	316	0.0e+00	497.1	COG0519	GMP synthase, PP-ATPase domain/subunit	315
2919590215	243	47.57	104	183	52	100	3.9e-03	11.4	COG1694	NTP pyrophosphatase, house-cleaning of non-canonical NTPs	102
2919590216	325	98.84	1	323	2	341	0.0e+00	485.3	COG1089	GDP-D-mannose dehydratase	345
2919590217	324	98.44	2	319	3	318	1.1e-54	180.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919590218	398	70.9	7	395	92	381	5.5e-24	80	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919590223	326	99.07	4	317	1	318	4.9e-81	267	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919590224	184	97.18	1	178	5	176	7.8e-64	208.8	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
2919590225	353	98.57	1	348	1	345	0.0e+00	481.6	COG1088	dTDP-D-glucose 4,6-dehydratase	340
2919590226	300	99.65	1	291	1	281	8.9e-94	308.1	COG1091	dTDP-4-dehydrorhamnose reductase	281
2919590227	289	99.31	1	289	1	289	1.5e-113	373.1	COG1209	dTDP-glucose pyrophosphorylase	286
2919590228	379	89.1	7	358	29	265	2.5e-59	195.3	COG0860	N-acetylmuramoyl-L-alanine amidase	231
2919590229	807	96.73	4	804	2	770	0.0e+00	955.5	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
2919590230	700	28.68	1	243	14	241	3.1e-44	56.2	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2919590230	700	48.3	321	700	412	795	3.1e-44	97	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2919590231	326	96.63	1	178	5	176	9.8e-46	150	COG4549	Uncharacterized protein YcnI	178
2919590233	433	65.22	12	418	184	558	6.1e-117	386.1	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
2919590236	434	98.8	13	434	5	414	0.0e+00	635.4	COG0112	Glycine/serine hydroxymethyltransferase	413
2919590237	170	96.15	1	155	1	150	7.7e-64	208.7	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
2919590238	384	89.73	1	148	4	134	2.4e-50	163.7	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
2919590238	384	99.09	150	371	2	219	6.5e-54	177	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
2919590239	213	97.07	1	213	1	199	6.5e-63	205.8	COG0307	Riboflavin synthase alpha chain	204
2919590240	173	92.76	11	162	11	151	4.2e-45	147.6	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
2919590241	161	92.16	1	154	10	150	5.1e-37	121.6	COG0781	Transcription termination factor NusB	151
2919590242	333	99.06	4	332	4	320	6.1e-81	266.2	COG0611	Thiamine monophosphate kinase	317
2919590244	715	99.29	1	715	4	701	0.0e+00	1052.9	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
2919590246	363	98.35	1	361	3	359	3.9e-101	333.1	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2919590247	632	55.79	301	429	108	242	1.2e-36	40.8	COG2202	PAS domain	232
2919590247	632	59.5	9	305	99	242	1.2e-36	86	COG2202	PAS domain	232
2919590247	632	96.49	414	631	5	224	1.0e-41	135.8	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919590248	236	96.85	23	231	5	219	4.4e-38	125.6	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2919590249	163	88	2	145	16	147	4.8e-29	95.6	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
2919590250	181	93.33	1	176	2	169	3.6e-53	174.6	COG5452	Uncharacterized protein	180
2919590251	176	65.92	21	171	59	176	7.1e-05	15.5	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
2919590252	344	97.64	4	341	3	333	4.8e-127	417.9	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
2919590253	325	98.77	4	325	4	325	0.0e+00	439.4	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2919590254	107	96.81	5	98	2	92	4.3e-30	98.3	COG0776	Bacterial nucleoid DNA-binding protein	94
2919590255	164	86.36	24	160	2	115	2.3e-18	61	COG0789	DNA-binding transcriptional regulator, MerR family	124
2919590257	336	92.54	1	299	6	253	3.6e-47	155.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919590258	1070	99.7	2	1041	2	1012	0.0e+00	1138.5	COG0841	Multidrug efflux pump subunit AcrB	1009
2919590259	384	98.46	1	377	4	387	2.7e-69	228.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919590260	106	94.74	1	106	4	111	1.8e-20	67.5	COG0607	Rhodanese-related sulfurtransferase	110
2919590261	429	64.3	32	404	88	350	2.0e-21	71.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919590265	144	99.32	3	142	2	146	7.4e-17	57.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919590266	208	74.58	9	200	26	201	2.1e-05	18.4	COG3637	Opacity protein and related surface antigens	199
2919590269	524	96.17	16	521	7	483	0.0e+00	614.5	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
2919590270	434	98.82	1	431	4	422	0.0e+00	458.5	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
2919590271	648	99.54	5	648	2	648	0.0e+00	930.3	COG2766	Predicted Ser/Thr protein kinase	649
2919590274	235	98.14	1	211	1	211	1.3e-61	202.5	COG0625	Glutathione S-transferase	211
2919590275	315	83.65	8	294	52	317	1.6e-67	222.6	COG0657	Acetyl esterase/lipase	312
2919590278	153	71.9	1	137	6	115	8.9e-33	107.9	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2919590279	355	58.59	76	306	34	207	3.4e-20	65.8	COG1533	DNA repair photolyase	297
2919590281	759	97.87	13	723	8	696	0.0e+00	891.3	COG1523	Pullulanase/glycogen debranching enzyme	697
2919590282	127	93.23	1	125	5	128	3.9e-34	111.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919590283	657	94.44	7	381	8	347	6.1e-73	239.7	COG0628	Predicted PurR-regulated permease PerM	355
2919590285	540	62.44	16	401	147	392	1.2e-51	171.1	COG0642	Signal transduction histidine kinase	336
2919590286	105	57.58	1	85	4	60	2.8e-05	18.6	COG3668	Plasmid stabilization system protein ParE	98
2919590287	346	45.02	183	324	110	258	8.5e-62	93.3	COG0790	TPR repeat	292
2919590287	346	58.01	66	246	65	256	8.5e-62	124.3	COG0790	TPR repeat	292
2919590288	219	83.89	5	218	30	206	4.0e-22	72.7	COG0352	Thiamine monophosphate synthase	211
2919590289	357	99.65	1	329	1	287	5.5e-107	351.6	COG0191	Fructose/tagatose bisphosphate aldolase	286
2919590290	399	97.74	1	399	7	395	0.0e+00	491.5	COG0126	3-phosphoglycerate kinase	395
2919590292	335	98.81	2	335	1	331	0.0e+00	485.5	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
2919590295	120	98.1	1	119	1	103	3.8e-25	82.3	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
2919590297	161	73.82	2	149	46	186	9.6e-42	137.5	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
2919590298	272	99.25	1	268	1	264	1.0e-103	340.6	COG1692	Calcineurin-like phosphoesterase	266
2919590300	337	85.93	45	337	37	268	6.3e-37	121.3	COG1360	Flagellar motor protein MotB	244
2919590301	117	84.5	1	117	15	123	1.0e-38	126.7	COG2852	Very-short-patch-repair endonuclease	129
2919590302	339	98.76	2	336	3	321	1.6e-85	281.4	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
2919590303	614	99.32	17	592	4	591	0.0e+00	589.5	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2919590304	84	89.33	9	84	6	72	7.9e-21	68.5	COG0254	Ribosomal protein L31	75
2919590305	175	93.71	7	174	10	173	4.4e-53	173.7	COG5317	Uncharacterized protein	175
2919590307	226	97.13	1	226	3	239	5.2e-80	262.6	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
2919590308	79	93.98	1	79	2	79	2.7e-31	102	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
2919590310	200	96.7	20	200	7	182	9.1e-85	277.4	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2919590311	460	88.07	16	438	42	388	7.6e-34	112.1	COG0642	Signal transduction histidine kinase	336
2919590312	424	98.31	3	417	2	409	0.0e+00	629.6	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
2919590313	244	96.48	13	243	8	226	2.5e-58	191.7	COG1451	Predicted metal-dependent hydrolase	223
2919590315	176	91.71	3	176	12	177	7.0e-47	153.7	COG5342	Invasion protein IalB, involved in pathogenesis	181
2919590317	670	67.73	399	655	21	232	1.1e-29	97.5	COG1216	Glycosyltransferase, GT2 family	305
2919590318	264	94.91	10	258	8	268	3.6e-85	279.6	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
2919590319	242	97.16	34	242	4	208	6.3e-78	255	COG0177	Endonuclease III	211
2919590320	173	98.78	8	171	2	163	9.7e-42	136.8	COG5488	Uncharacterized membrane protein	164
2919590321	686	85.03	91	548	56	390	8.1e-62	204	COG0642	Signal transduction histidine kinase	336
2919590322	1937	63.1	90	156	30	82	9.4e-120	8.4	COG2770	HAMP domain	83
2919590322	1937	85.71	1645	1773	7	120	3.0e-75	52.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919590322	1937	88.72	1200	1649	8	125	3.0e-75	69.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919590322	1937	89.29	812	892	2	76	9.4e-120	32.1	COG2770	HAMP domain	83
2919590322	1937	90.48	904	980	2	77	9.4e-120	31	COG2770	HAMP domain	83
2919590322	1937	93.23	1790	1921	6	129	3.0e-75	119.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919590322	1937	96.43	168	248	2	82	9.4e-120	46.2	COG2770	HAMP domain	83
2919590322	1937	96.43	260	340	2	82	9.4e-120	44.8	COG2770	HAMP domain	83
2919590322	1937	96.43	352	432	2	82	9.4e-120	48.2	COG2770	HAMP domain	83
2919590322	1937	96.43	444	524	2	82	9.4e-120	51.6	COG2770	HAMP domain	83
2919590322	1937	96.43	536	616	2	82	9.4e-120	48.2	COG2770	HAMP domain	83
2919590322	1937	96.43	628	708	2	82	9.4e-120	44	COG2770	HAMP domain	83
2919590322	1937	96.43	720	800	2	82	9.4e-120	47.7	COG2770	HAMP domain	83
2919590324	247	91.04	1	239	5	248	1.8e-55	182.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919590325	544	98.67	14	539	6	526	0.0e+00	787.4	COG4108	Peptide chain release factor RF-3	528
2919590326	150	93.23	2	129	7	130	1.9e-23	77.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919590328	463	99.15	3	463	3	470	4.5e-74	243.9	COG1749	Flagellar hook protein FlgE	423
2919590329	624	99.49	1	624	1	585	1.7e-71	236.1	COG1256	Flagellar hook-associated protein FlgK	552
2919590334	120	47.95	14	120	22	103	8.0e-12	40.1	COG3951	Rod binding protein domain	166
2919590335	371	97.53	4	371	9	364	0.0e+00	466.6	COG1706	Flagellar basal body P-ring protein FlgI	365
2919590337	139	99.17	19	138	1	119	1.3e-41	136.3	COG1734	RNA polymerase-binding transcription factor DksA	120
2919590339	248	95.24	5	246	11	230	4.1e-66	217.2	COG2063	Flagellar basal body L-ring protein FlgH	230
2919590340	361	68.18	180	345	70	219	7.2e-25	81.8	COG1261	Flagella basal body P-ring formation protein FlgA	220
2919590341	263	98.87	1	262	2	263	6.6e-89	292.3	COG4786	Flagellar basal body rod protein FlgG	265
2919590342	246	99.25	1	243	1	263	1.0e-64	212.9	COG4786	Flagellar basal body rod protein FlgG	265
2919590343	170	96.86	10	170	6	159	4.4e-22	72.8	COG1580	Flagellar basal body-associated protein FliL	159
2919590344	406	84.68	75	398	46	327	1.4e-57	189.4	COG1868	Flagellar motor switch protein FliM	332
2919590345	178	27.73	139	177	32	64	1.5e-03	10.1	COG2018	Predicted regulator of Ras-like GTPase activity, Roadblock/LC7/MglB family	119
2919590345	178	49.58	37	106	6	64	1.5e-03	4.7	COG2018	Predicted regulator of Ras-like GTPase activity, Roadblock/LC7/MglB family	119
2919590346	288	74.36	62	274	43	187	7.0e-21	69.1	COG3334	Flagellar motility protein MotE, a chaperone for MotC folding	192
2919590347	163	80.95	1	156	9	161	9.0e-14	46.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2919590348	183	92.98	1	163	4	162	3.8e-47	154.7	COG3153	Predicted N-acetyltransferase YhbS	171
2919590349	388	93.92	5	388	24	394	3.6e-99	326.4	COG0019	Diaminopimelate decarboxylase	394
2919590352	522	92.71	4	522	34	529	0.0e+00	573.2	COG3131	Periplasmic glucans biosynthesis protein	534
2919590353	167	91.01	7	166	12	183	1.1e-22	75.1	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2919590355	481	93.98	4	473	20	472	1.3e-25	84.2	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2919590356	394	91.68	2	394	38	467	1.3e-40	133.8	COG0277	FAD/FMN-containing dehydrogenase	459
2919590357	453	98.75	15	435	5	400	2.0e-89	294.6	COG0247	Fe-S oxidoreductase	388
2919590358	446	18.82	90	171	12	65	2.0e-68	4.1	COG4976	Predicted methyltransferase, contains TPR repeat	287
2919590358	446	21.25	22	112	5	65	2.0e-68	11.4	COG4976	Predicted methyltransferase, contains TPR repeat	287
2919590358	446	21.95	131	205	14	76	2.0e-68	10.8	COG4976	Predicted methyltransferase, contains TPR repeat	287
2919590358	446	93.03	161	440	15	281	2.0e-68	209.9	COG4976	Predicted methyltransferase, contains TPR repeat	287
2919590359	74	63.73	1	71	13	77	1.8e-24	79.7	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2919590361	470	99.57	7	468	2	461	0.0e+00	748.8	COG0114	Fumarate hydratase class II	462
2919590362	463	94.06	5	463	25	420	3.5e-88	290.6	COG2124	Cytochrome P450	411
2919590363	206	100	1	205	1	157	8.7e-65	206.2	COG3814	Uncharacterized protein	157
2919590365	265	78.26	8	264	43	222	1.0e-14	47.7	COG1266	Membrane protease YdiL, CAAX protease family	226
2919590366	264	99.27	1	264	3	273	3.2e-117	385.1	COG0207	Thymidylate synthase	268
2919590367	167	98.82	7	166	2	169	8.7e-45	147	COG0262	Dihydrofolate reductase	167
2919590368	389	93.02	62	368	8	287	1.3e-56	186.3	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2919590369	320	97.01	1	297	5	296	5.9e-64	210.6	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2919590370	514	20.55	407	514	277	351	1.8e-121	24.6	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2919590370	514	92.05	2	402	24	359	1.8e-121	380.6	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2919590372	298	98.58	79	290	3	211	1.2e-67	221.6	COG0560	Phosphoserine phosphatase	212
2919590373	306	93.51	10	304	3	290	1.3e-90	297.8	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
2919590374	288	99.3	2	287	2	285	1.5e-105	346.9	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2919590375	685	98.2	32	683	1	600	0.0e+00	869.2	COG1966	Carbon starvation protein CstA	575
2919590376	74	92.31	6	74	6	65	6.1e-22	71.8	COG2879	Uncharacterized short protein YbdD, DUF466 family	65
2919590378	153	81.94	2	142	20	137	1.3e-11	38.8	COG3793	Tellurite resistance protein	144
2919590379	1074	99.51	2	1065	5	1013	0.0e+00	786.8	COG0841	Multidrug efflux pump subunit AcrB	1009
2919590380	231	96.4	4	221	7	220	1.5e-53	176.3	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2919590383	237	95.61	2	231	5	222	1.8e-74	244	COG0120	Ribose 5-phosphate isomerase	227
2919590384	187	76.09	31	184	24	163	9.1e-15	49.6	COG3184	Uncharacterized protein	183
2919590385	461	99.34	3	449	3	454	0.0e+00	455.4	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2919590388	463	90.59	5	458	39	423	3.1e-60	198.6	COG0840	Methyl-accepting chemotaxis protein	408
2919590389	460	99.55	1	446	2	445	0.0e+00	742.8	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
2919590390	936	64.25	422	934	216	641	0.0e+00	432	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919590390	936	84.52	181	259	11	81	1.1e-07	26.8	COG2770	HAMP domain	83
2919590391	126	71.09	12	126	36	126	2.2e-10	35.4	COG3794	Plastocyanin	128
2919590392	422	95.9	6	413	14	387	1.3e-36	120.8	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919590394	446	97.29	1	446	11	477	1.7e-116	384.5	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2919590395	429	97.95	1	428	5	433	0.0e+00	435.8	COG1253	Hemolysin or related protein, contains CBS domains	429
2919590396	402	49.09	221	402	8	195	4.9e-32	26.1	COG0477	MFS family permease	338
2919590396	402	61.1	16	249	2	235	4.9e-32	82.6	COG0477	MFS family permease	338
2919590397	741	75.88	563	728	46	196	5.1e-29	96.5	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2919590399	173	88.48	9	167	11	156	2.0e-51	167.9	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
2919590401	460	99.35	4	459	1	462	0.0e+00	520.6	COG0215	Cysteinyl-tRNA synthetase	464
2919590403	200	87.32	1	193	16	194	2.6e-59	194.6	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2919590404	542	86.01	229	533	36	281	7.7e-20	66.3	COG1652	Nucleoid-associated protein YgaU, contains BON and LysM domains	269
2919590405	639	99.8	107	602	2	497	0.0e+00	748.8	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
2919590406	236	92.25	1	226	18	255	8.1e-46	150.3	COG0688	Phosphatidylserine decarboxylase	239
2919590407	279	96.2	21	261	8	235	1.7e-64	212	COG1183	Phosphatidylserine synthase	234
2919590408	142	96.95	1	139	3	129	3.9e-48	157.5	COG1970	Large-conductance mechanosensitive channel	130
2919590411	246	92.47	57	233	8	179	1.3e-49	162.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919590412	268	94.92	1	250	7	249	2.2e-74	244.6	COG0121	Predicted glutamine amidotransferase	252
2919590413	853	11.82	687	792	445	514	7.0e-22	5.2	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2919590413	853	69.76	9	548	61	473	7.0e-22	64.8	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2919590414	408	71.33	7	279	28	241	3.8e-76	250.5	COG3034	Murein L,D-transpeptidase YafK	298
2919590415	301	97.07	10	283	6	270	5.8e-29	95.5	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2919590416	492	96.14	22	492	7	479	6.5e-96	316.1	COG0531	Amino acid transporter	466
2919590417	227	99.08	8	223	2	217	1.3e-59	196.2	COG0819	Thiaminase	218
2919590418	224	97.16	15	222	3	207	2.1e-44	145.8	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919590419	478	61.07	14	464	147	375	3.6e-41	135.4	COG4585	Signal transduction histidine kinase	365
2919590422	564	67.69	1	391	39	390	2.2e-118	390.4	COG0513	Superfamily II DNA and RNA helicase	513
2919590423	367	88.92	11	367	39	367	4.7e-85	279.9	COG0387	Ca2+/H+ antiporter	368
2919590424	243	86.94	5	242	3	235	2.3e-49	162.4	COG1018	Ferredoxin-NADP reductase	266
2919590425	201	73.36	1	201	56	267	8.4e-52	170.6	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2919590426	250	83.87	1	246	25	258	4.2e-15	50.9	COG0500	SAM-dependent methyltransferase	257
2919590428	390	54.74	32	344	115	316	7.5e-20	64.8	COG4421	Capsular polysaccharide biosynthesis protein	368
2919590429	414	96.25	1	343	11	344	3.1e-105	346.5	COG2951	Membrane-bound lytic murein transglycosylase B	343
2919590430	195	98.95	1	195	1	189	1.7e-42	139.8	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
2919590431	379	51.22	73	348	116	304	7.4e-18	59	COG4421	Capsular polysaccharide biosynthesis protein	368
2919590432	356	38.35	61	340	54	160	1.6e-04	16.7	COG0500	SAM-dependent methyltransferase	257
2919590433	187	93.92	1	146	6	144	6.4e-53	172.8	COG4957	Predicted transcriptional regulator	148
2919590436	265	83.8	24	262	43	280	2.6e-52	172.2	COG2801	Transposase InsO and inactivated derivatives	232
2919590437	116	61.54	1	107	6	77	2.2e-13	45.1	COG2963	Transposase and inactivated derivatives	116
2919590438	243	94.23	1	243	11	255	3.4e-47	155.9	COG1484	DNA replication protein DnaC	254
2919590439	413	66.55	1	208	85	273	3.3e-23	76.6	COG4584	Transposase	278
2919590440	264	90.94	9	264	15	255	6.2e-35	115	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2919590441	152	51.41	1	151	132	277	1.7e-30	100.8	COG2801	Transposase InsO and inactivated derivatives	232
2919590443	368	60.56	75	137	24	66	2.2e-04	13.7	COG5420	Uncharacterized protein	71
2919590444	754	79.55	1	270	5	253	3.1e-19	63.2	COG1216	Glycosyltransferase, GT2 family	305
2919590444	754	94.87	327	730	5	392	5.3e-50	164.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919590445	350	76.7	12	284	6	219	1.8e-15	51.9	COG0500	SAM-dependent methyltransferase	257
2919590446	183	27.08	36	175	171	258	1.6e-04	15.4	COG2826	Transposase and inactivated derivatives, IS30 family	318
2919590447	164	54.74	14	138	74	177	4.0e-22	73.1	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2919590451	43	55.38	1	43	25	60	4.0e-15	48.8	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
2919590452	224	97.94	20	218	3	192	4.2e-63	206.5	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
2919590454	331	99.13	4	328	2	342	0.0e+00	481.2	COG1089	GDP-D-mannose dehydratase	345
2919590455	304	92.83	1	301	20	317	3.9e-47	155.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919590456	244	73.13	1	244	23	267	9.7e-76	249.8	COG0836	Mannose-1-phosphate guanylyltransferase	333
2919590457	46	8.02	1	44	139	174	5.7e-04	12	COG2610	H+/gluconate symporter or related permease	442
2919590458	427	45.42	164	416	61	194	1.2e-04	16.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919590459	192	96.89	21	180	1	156	1.2e-56	184.9	COG3265	Gluconate kinase	161
2919590460	271	98.53	7	271	3	270	2.5e-51	169.4	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
2919590462	300	81.16	11	82	5	60	2.7e-04	14.2	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2919590462	300	95.35	120	292	3	166	2.7e-39	129	COG0703	Shikimate kinase	172
2919590463	286	92.86	82	281	6	187	2.5e-79	258.9	COG1045	Serine acetyltransferase	194
2919590466	245	94.24	38	234	11	190	1.1e-57	189.2	COG3672	Predicted transglutaminase-like cysteine proteinase	191
2919590467	208	97.38	1	197	4	189	3.3e-55	181.2	COG3672	Predicted transglutaminase-like cysteine proteinase	191
2919590469	208	77.99	1	182	21	183	3.1e-43	141.8	COG5388	Uncharacterized protein	209
2919590470	272	85.09	5	271	17	210	3.9e-39	128.8	COG0705	Membrane associated serine protease, rhomboid family	228
2919590471	143	95.09	1	122	9	163	3.0e-28	93.5	COG0517	CBS domain	117
2919590472	347	93.1	29	346	6	302	4.7e-83	273.5	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2919590473	139	91.07	13	124	10	111	1.7e-41	135	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
2919590474	263	92.89	66	262	14	196	1.1e-80	263.9	COG0302	GTP cyclohydrolase I	195
2919590475	152	95.36	1	149	2	145	1.3e-35	116.9	COG0822	NifU homolog involved in Fe-S cluster formation	150
2919590476	117	79.35	2	87	10	82	1.2e-29	96	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
2919590477	162	96.18	2	159	2	152	8.2e-23	75.4	COG2405	Predicted nucleic acid-binding protein, contains PIN domain	157
2919590479	675	98.82	34	651	3	589	0.0e+00	852.2	COG0441	Threonyl-tRNA synthetase	589
2919590480	84	94.51	1	84	3	88	7.8e-10	33.4	COG2026	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system	90
2919590481	124	84.06	63	122	3	60	1.3e-07	25.2	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2919590482	464	96.05	9	464	8	445	2.2e-120	396.8	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2919590484	317	96.68	9	298	5	295	2.7e-37	122.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919590486	199	86.57	15	199	25	211	1.0e-20	68.9	COG0778	Nitroreductase	207
2919590487	140	89.39	3	138	14	131	1.0e-46	152.3	COG5649	Uncharacterized protein	132
2919590488	316	97.27	126	306	6	183	4.0e-45	147.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919590489	200	93.51	1	192	9	181	1.3e-38	126.9	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2919590490	220	68.22	8	126	31	118	2.0e-13	44	COG3677	Transposase	129
2919590494	542	91.48	1	346	7	339	2.7e-54	179.4	COG5330	Uncharacterized conserved protein, DUF2336 family	364
2919590495	256	70.88	3	249	47	248	1.3e-52	173	COG0061	NAD kinase	281
2919590496	109	96.15	2	105	3	102	2.5e-30	98.8	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
2919590497	322	78.46	70	320	16	219	7.8e-31	102.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2919590499	280	81.99	10	241	24	237	1.2e-07	24.5	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2919590500	508	98.39	3	503	5	493	1.8e-100	331.5	COG1233	Phytoene dehydrogenase-related protein	487
2919590503	403	66.89	189	400	93	288	1.5e-18	61.6	COG0842	ABC-type multidrug transport system, permease component	286
2919590504	342	78.1	12	322	5	243	2.3e-67	222	COG1131	ABC-type multidrug transport system, ATPase component	293
2919590505	141	85.43	1	136	16	144	2.3e-24	80.1	COG4704	Uncharacterized conserved protein, DUF2141 family	151
2919590506	515	97.18	1	491	6	488	1.5e-95	315.4	COG1233	Phytoene dehydrogenase-related protein	487
2919590507	280	94.68	12	273	9	257	8.3e-47	153.9	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2919590508	158	90.57	1	144	14	157	1.3e-34	113.2	COG2030	Acyl dehydratase	159
2919590509	200	64.21	5	199	25	216	6.7e-35	115.1	COG1230	Co/Zn/Cd efflux system component	296
2919590510	281	37.54	1	214	47	156	5.3e-05	15.8	COG1408	Predicted phosphohydrolase, MPP superfamily	284
2919590512	125	82.18	6	101	14	96	1.4e-24	80.3	COG2154	Pterin-4a-carbinolamine dehydratase	101
2919590513	330	88.66	1	318	4	300	1.0e-17	58.7	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919590514	244	94.19	1	244	12	254	3.9e-49	161.8	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2919590515	252	89.24	13	246	7	230	7.7e-65	213.1	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2919590517	108	97.27	1	108	3	109	2.0e-41	134.9	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2919590518	415	96.91	2	398	11	418	9.6e-120	395.1	COG0232	dGTP triphosphohydrolase	412
2919590519	146	94.96	12	146	5	136	5.3e-32	105.1	COG0824	Acyl-CoA thioesterase FadM	137
2919590520	585	100	1	584	1	581	0.0e+00	522	COG0018	Arginyl-tRNA synthetase	577
2919590522	335	74.34	1	330	7	316	9.3e-81	266.4	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2919590523	97	53.19	1	79	1	50	3.0e-18	60.6	COG1826	Sec-independent protein translocase protein TatA	94
2919590524	157	69.15	1	121	1	65	4.0e-16	53	COG1826	Sec-independent protein translocase protein TatA	94
2919590525	266	95.75	8	264	3	250	5.0e-82	269.5	COG0805	Sec-independent protein secretion pathway component TatC	255
2919590526	427	99.77	1	426	1	430	0.0e+00	581	COG0172	Seryl-tRNA synthetase	429
2919590527	254	95.7	1	252	1	245	2.4e-82	270.6	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
2919590528	225	94.79	17	225	4	203	3.3e-48	158.4	COG2518	Protein-L-isoaspartate O-methyltransferase	209
2919590529	494	95.57	113	494	3	304	1.2e-47	154.9	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2919590530	291	97.58	2	291	4	285	8.4e-117	383.7	COG2607	Predicted ATPase, AAA+ superfamily	287
2919590531	111	91.75	11	110	5	93	4.4e-30	98.2	COG1862	Preprotein translocase subunit YajC	97
2919590532	535	99.62	1	535	1	521	0.0e+00	548	COG0342	Preprotein translocase subunit SecD	506
2919590533	314	97.4	4	307	3	302	5.1e-100	328.8	COG0341	Preprotein translocase subunit SecF	305
2919590534	129	91.34	4	127	12	127	3.0e-43	141.4	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
2919590535	293	95.85	15	293	9	285	2.6e-57	188.7	COG1562	Phytoene/squalene synthetase	288
2919590536	572	99.81	13	566	1	526	0.0e+00	548.1	COG1620	L-lactate permease	522
2919590537	182	82.35	9	174	6	159	4.9e-20	66.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2919590538	478	98.86	2	469	3	436	0.0e+00	662.3	COG1206	Folate-dependent tRNA-U54 methylase TrmFO/GidA	439
2919590539	221	22.01	22	218	359	509	2.1e-18	60.2	COG1289	Uncharacterized membrane protein YccC	674
2919590540	312	86.58	6	305	44	359	4.1e-42	138.7	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2919590541	183	94.09	6	183	5	179	1.8e-43	142.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919590542	232	92.5	2	232	17	238	2.2e-45	149.2	COG5343	Anti-sigma-K factor RskA	240
2919590543	187	73.17	3	187	50	199	1.2e-53	176.6	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
2919590545	1022	99.57	61	1007	4	940	0.0e+00	1477.1	COG0178	Excinuclease UvrABC ATPase subunit	935
2919590546	685	81.41	212	680	78	423	3.5e-50	164.8	COG0840	Methyl-accepting chemotaxis protein	408
2919590548	930	91.23	310	929	18	225	1.7e-44	145.3	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919590549	272	16.97	4	65	11	47	2.3e-13	7.9	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919590549	272	43.12	94	215	123	216	2.3e-13	35.1	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919590550	289	85.56	21	272	34	264	1.4e-75	248	COG3757	Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family	269
2919590551	147	48.44	3	146	3	142	3.6e-13	43.4	COG5483	Uncharacterized conserved protein, DUF488 family	289
2919590558	101	49.65	1	72	72	141	5.3e-23	76.3	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
2919590559	239	91.11	17	238	10	214	6.6e-81	265.1	COG0321	Lipoate-protein ligase B	221
2919590560	295	93.77	1	293	11	296	1.5e-90	297.9	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2919590562	364	99.43	1	363	1	347	1.1e-130	429.8	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
2919590563	391	98.12	16	386	2	366	0.0e+00	525.5	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
2919590564	686	64.71	145	686	213	641	1.1e-128	424.5	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919590567	215	78.97	2	211	52	250	6.2e-39	128	COG2134	CDP-diacylglycerol pyrophosphatase	252
2919590577	170	93.92	16	165	3	141	3.3e-51	167.5	COG4957	Predicted transcriptional regulator	148
2919590580	342	99.69	5	327	2	326	8.9e-77	253	COG3547	Transposase	303
2919590584	239	74.57	2	223	43	215	2.1e-15	51.8	COG0671	Membrane-associated phospholipid phosphatase	232
2919590585	106	32.64	7	105	12	58	9.5e-04	13.4	COG3793	Tellurite resistance protein	144
2919590588	2445	15.89	1811	1906	399	487	1.1e-26	34.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919590588	2445	24.29	1022	1310	302	437	1.1e-26	7.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919590588	2445	31.96	1294	1567	265	443	1.1e-26	20.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919590588	2445	35	691	1079	264	459	1.1e-26	25.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919590588	2445	45.71	1552	1838	197	452	1.1e-26	57.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919590589	79	13.45	1	79	31	108	2.6e-29	96.5	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2919590591	226	89.66	7	223	14	221	1.2e-44	146.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
2919590593	120	65.91	13	74	10	67	3.5e-04	14.5	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2919590594	167	94.48	22	166	6	142	1.5e-31	103.5	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2919590596	310	94.49	6	258	5	244	2.8e-64	211.1	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
2919590597	288	96.74	3	278	7	273	4.8e-66	217.2	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2919590598	200	91.39	3	200	14	204	4.4e-40	131.6	COG3932	Uncharacterized conserved protein	209
2919590600	532	98.81	9	518	4	502	0.0e+00	724.9	COG3046	Uncharacterized protein related to deoxyribodipyrimidine photolyase	505
2919590601	244	97.76	1	240	6	267	7.7e-44	144.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919590602	288	91.88	1	279	3	285	4.3e-29	96	COG0223	Methionyl-tRNA formyltransferase	307
2919590603	49	79.63	1	49	5	47	1.0e-21	71.3	COG4338	Uncharacterized protein	54
2919590604	207	95.5	1	200	4	194	2.6e-51	168.7	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
2919590605	342	84.28	1	338	4	346	9.9e-26	84.3	COG0303	Molybdopterin biosynthesis enzyme	404
2919590606	231	57.81	2	231	111	284	5.4e-51	168	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2919590607	107	33.55	6	107	2	102	8.1e-32	105.2	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2919590608	373	95.9	13	369	4	354	5.8e-66	217.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919590609	90	97.33	1	75	1	73	2.2e-28	92	COG0361	Translation initiation factor IF-1	75
2919590610	748	91.64	4	746	5	749	0.0e+00	788.8	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
2919590611	243	90.87	1	231	6	234	2.0e-46	152.7	COG1381	Recombinational DNA repair protein (RecF pathway)	251
2919590613	228	93.68	45	227	8	185	4.5e-56	183.7	COG3703	Cation transport regulator ChaC	190
2919590614	1183	99.57	7	1183	3	1154	0.0e+00	1277.6	COG0587	DNA polymerase III, alpha subunit	1139
2919590616	237	94.69	16	237	6	219	2.9e-76	250	COG1136	ABC-type lipoprotein export system, ATPase component	226
2919590617	435	99.51	26	435	2	409	0.0e+00	445.1	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2919590618	441	30.74	251	440	365	526	0.0e+00	168.1	COG0442	Prolyl-tRNA synthetase	500
2919590618	441	43.45	1	274	1	229	0.0e+00	342.7	COG0442	Prolyl-tRNA synthetase	500
2919590619	440	93.14	18	432	17	410	2.7e-115	379.5	COG0738	Fucose permease	422
2919590620	107	64.04	31	104	7	63	5.8e-14	46.1	COG5454	Predicted secreted protein	89
2919590621	134	97.95	3	133	2	144	1.4e-18	63.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919590622	557	98.54	1	555	6	544	0.0e+00	519.2	COG0595	mRNA degradation ribonuclease J1/J2	555
2919590623	269	98.74	19	265	2	237	1.5e-59	196	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
2919590624	481	98.53	8	481	5	473	0.0e+00	533.7	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
2919590625	506	98.39	3	499	5	494	0.0e+00	660.9	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
2919590626	703	99.51	2	692	2	615	0.0e+00	763.3	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2919590627	101	100	1	101	1	100	1.1e-40	132.1	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
2919590628	206	100	1	173	1	168	2.1e-54	178.1	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
2919590629	162	89.14	1	162	5	160	1.6e-56	185.1	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
2919590630	340	98.5	1	336	4	331	0.0e+00	441	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
2919590631	693	99.59	1	693	1	728	0.0e+00	726.5	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
2919590632	433	97.88	1	420	8	422	0.0e+00	625.1	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2919590633	448	80.45	306	447	24	130	1.8e-32	107.4	COG3743	 Predicted 5' DNA nuclease, flap endonuclease-1-like, helix-3-turn-helix (H3TH) domain	133
2919590633	448	95.78	7	174	6	164	3.2e-56	183.3	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2919590634	396	98.24	1	396	8	398	0.0e+00	601.3	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
2919590635	215	97.22	15	192	5	179	1.9e-63	208	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
2919590636	195	80.41	28	195	11	166	1.4e-83	273.1	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
2919590637	121	97.54	1	121	3	121	1.3e-47	155.3	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
2919590639	327	59.68	18	327	56	354	1.9e-40	133.6	COG0753	Catalase	496
2919590640	166	59.07	8	166	87	213	9.0e-31	101.9	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
2919590643	830	85.53	270	691	52	388	8.7e-54	176.3	COG0642	Signal transduction histidine kinase	336
2919590643	830	93.23	704	830	6	129	1.4e-19	63.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919590644	157	96.15	1	156	1	150	4.7e-38	125.1	COG2954	CYTH domain, found in class IV adenylate cyclase and various triphosphatases	156
2919590645	154	87.79	2	150	11	161	1.2e-15	52.2	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2919590646	325	81.54	52	306	21	232	1.8e-29	97.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2919590647	256	72.97	10	132	40	147	2.8e-12	39.5	COG5501	Predicted secreted protein	148
2919590648	206	45.61	57	183	61	112	3.4e-05	17.4	COG0607	Rhodanese-related sulfurtransferase	110
2919590649	186	93.92	11	186	9	178	1.8e-48	158.9	COG3038	Cytochrome b561	181
2919590651	141	70.73	4	141	26	141	2.8e-17	57.9	COG2010	Cytochrome c, mono- and diheme variants	150
2919590653	226	59.76	16	197	60	209	2.7e-36	118.9	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2919590654	627	82.28	2	627	120	755	1.5e-127	420.5	COG4993	Glucose dehydrogenase	773
2919590655	217	97.16	1	211	2	206	1.8e-53	175.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919590656	494	98.99	2	494	6	497	0.0e+00	590.8	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
2919590657	288	80.6	51	277	31	217	8.3e-03	11.8	COG0671	Membrane-associated phospholipid phosphatase	232
2919590659	807	98.72	3	785	9	782	0.0e+00	1138.4	COG0466	ATP-dependent Lon protease, bacterial type	782
2919590660	423	98.53	16	420	1	403	0.0e+00	677.4	COG1219	ATP-dependent protease Clp, ATPase subunit	408
2919590661	209	96.5	10	209	3	195	1.7e-85	280.3	COG0740	ATP-dependent protease ClpP, protease subunit	200
2919590662	461	98.44	1	447	3	443	2.3e-126	416.5	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
2919590664	496	99.59	24	496	1	482	2.7e-58	192.7	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2919590665	504	96.53	215	499	9	286	6.3e-77	253.3	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
2919590665	504	97.07	4	200	5	203	2.4e-58	191.6	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
2919590666	112	100	1	112	1	112	2.2e-48	157.8	COG0347	Nitrogen regulatory protein PII	112
2919590667	470	99.55	3	470	2	445	0.0e+00	569.9	COG0174	Glutamine synthetase	443
2919590668	317	86.1	20	306	23	276	1.1e-14	47.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919590670	192	93.48	5	189	5	176	1.3e-30	100.8	COG0431	NAD(P)H-dependent FMN reductase	184
2919590672	767	99.58	11	728	3	710	0.0e+00	633.8	COG0557	Exoribonuclease R	706
2919590673	160	92.86	5	129	8	124	1.2e-42	138.9	COG5349	Uncharacterized conserved protein, DUF983 family	126
2919590674	251	86.63	21	231	13	161	8.3e-19	62.2	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2919590675	390	47	201	389	7	186	9.0e-24	46	COG0477	MFS family permease	338
2919590675	390	52.22	12	210	7	206	9.0e-24	38.2	COG0477	MFS family permease	338
2919590676	55	96.08	3	53	3	51	3.5e-24	79.4	COG0267	Ribosomal protein L33	50
2919590677	149	69.14	5	141	42	153	2.1e-09	32.3	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2919590678	77	96	1	77	1	72	6.3e-24	78.6	COG3798	Uncharacterized protein	75
2919590679	492	57.18	113	490	172	414	1.5e-42	140.4	COG0840	Methyl-accepting chemotaxis protein	408
2919590682	95	95	1	95	1	95	9.5e-24	77.9	COG0011	Uncharacterized conserved protein YqgV, UPF0045/DUF77 family	100
2919590684	443	96.74	18	440	14	428	3.9e-107	353.3	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2919590685	454	41.11	21	374	119	428	1.7e-02	8.1	COG0643	Chemotaxis protein histidine kinase CheA	716
2919590686	147	97.12	10	147	4	138	5.5e-43	140.7	COG0848	Biopolymer transport protein ExbD	137
2919590687	240	99.54	22	235	1	215	1.1e-69	229.2	COG0811	Biopolymer transport protein ExbB/TolQ	216
2919590688	139	93.53	7	139	5	134	1.1e-41	136.4	COG0824	Acyl-CoA thioesterase FadM	137
2919590689	351	95.48	8	336	13	329	0.0e+00	498.5	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
2919590691	458	96.58	4	458	14	437	2.9e-45	149.4	COG3659	Carbohydrate-selective porin OprB	439
2919590692	561	86.59	132	556	56	423	3.5e-55	180.6	COG0840	Methyl-accepting chemotaxis protein	408
2919590693	165	98.09	1	156	1	154	1.7e-63	207.6	COG2193	Bacterioferritin (cytochrome b1)	157
2919590694	308	89.63	1	308	5	315	2.0e-106	350.3	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2919590695	717	95.36	13	701	3	680	0.0e+00	640	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2919590696	423	77.27	22	350	17	288	2.3e-15	44.1	COG1566	Multidrug resistance efflux pump	352
2919590700	210	95.29	31	210	3	184	2.3e-44	146.2	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
2919590705	352	49.43	59	352	147	320	3.5e-58	192.2	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2919590706	209	55.11	2	205	156	349	3.9e-39	129.1	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2919590707	358	73.08	2	298	18	283	4.3e-32	105.7	COG5330	Uncharacterized conserved protein, DUF2336 family	364
2919590708	723	93.95	2	722	45	805	0.0e+00	487.5	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2919590710	203	52.48	7	151	111	237	1.4e-08	28.9	COG2202	PAS domain	232
2919590712	401	94.43	3	393	11	383	2.8e-36	119.1	COG2814	Predicted arabinose efflux permease, MFS family	394
2919590713	813	96.5	553	806	2	249	1.7e-91	299.9	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2919590713	813	96.61	21	255	6	233	1.3e-64	211.7	COG3300	MHYT domain, NO-binding membrane sensor	236
2919590713	813	97.81	363	542	5	183	6.3e-53	173	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919590714	490	84.63	66	460	9	355	1.0e-42	137.7	COG4320	Uncharacterized conserved protein, DUF2252 family	410
2919590715	448	95.16	4	446	19	411	3.2e-125	412.7	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2919590717	486	97.64	4	456	4	417	1.3e-57	189	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2919590719	44	9.85	8	44	2	34	9.0e-15	49.5	COG0836	Mannose-1-phosphate guanylyltransferase	333
2919590720	231	86.67	5	231	31	225	6.6e-72	235.8	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2919590721	468	25.59	301	440	344	462	2.4e-37	49.1	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2919590721	468	56.77	1	281	19	282	2.4e-37	79.1	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2919590722	350	40.11	8	263	6	149	1.7e-17	58.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2919590723	308	57.38	1	297	4	209	2.7e-19	64.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2919590725	491	98.13	1	471	2	474	6.7e-42	138	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2919590726	384	91.69	10	383	31	405	4.0e-37	123.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919590727	373	93.89	1	362	12	395	1.1e-16	56	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919590729	276	30.25	46	244	155	262	3.7e-11	37.2	COG4124	Beta-mannanase	355
2919590732	525	12.5	13	101	196	239	1.6e-17	12.5	COG1566	Multidrug resistance efflux pump	352
2919590732	525	57.67	131	376	90	292	1.6e-17	46.3	COG1566	Multidrug resistance efflux pump	352
2919590734	657	82.38	68	510	19	434	1.4e-58	193	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2919590735	157	26.28	10	147	7	47	4.6e-07	25	COG2165	Type II secretory pathway, pseudopilin PulG	149
2919590736	125	33.83	5	106	8	75	6.3e-07	24	COG4795	Type II secretory pathway, component PulJ	194
2919590737	210	39.74	7	124	5	66	4.1e-09	31.2	COG2165	Type II secretory pathway, pseudopilin PulG	149
2919590738	310	65.74	14	239	4	216	5.5e-15	46.9	COG3156	Type II secretory pathway, component PulK	323
2919590739	183	74.29	10	182	51	206	2.1e-33	110	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
2919590741	117	82.69	1	116	25	153	1.6e-14	49.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
2919590743	788	91.72	39	777	26	590	1.0e-121	400.7	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
2919590747	577	96.26	93	575	19	507	0.0e+00	537.1	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2919590748	403	98.99	1	403	1	394	1.0e-85	282.3	COG1459	Type II secretory pathway, component PulF	397
2919590752	247	93.58	6	226	13	216	1.0e-19	65.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919590754	780	98.82	133	779	7	592	0.0e+00	654.8	COG1982	Arginine/lysine/ornithine decarboxylase	557
2919590755	58	42.24	4	55	3	51	1.3e-02	9.8	COG5336	FoF1-type ATP synthase assembly protein I	116
2919590757	273	84.05	2	266	2	333	6.5e-25	79.6	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2919590761	616	98.65	16	614	7	590	7.5e-105	346.1	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2919590763	445	98.13	36	383	3	369	5.5e-91	299.5	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2919590765	124	92.48	1	124	6	128	1.1e-36	120.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919590766	457	99.77	15	457	1	434	0.0e+00	458.6	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2919590767	431	98.54	29	431	2	407	0.0e+00	469.5	COG0004	Ammonia channel protein AmtB	409
2919590768	615	96.47	1	605	16	617	1.1e-103	342.6	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
2919590769	332	82.7	27	327	60	365	5.3e-86	283.1	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2919590771	287	55.35	1	97	6	93	1.5e-14	8.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2919590771	287	56.6	153	287	67	156	1.5e-14	41.4	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2919590772	226	25.73	2	67	33	76	3.6e-19	27.3	COG3652	Predicted outer membrane protein	170
2919590772	226	41.52	135	226	97	167	3.6e-19	36	COG3652	Predicted outer membrane protein	170
2919590773	222	97.12	1	207	3	204	7.0e-53	173.9	COG0288	Carbonic anhydrase	207
2919590774	174	76.74	3	172	18	149	1.5e-14	48.7	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2919590775	260	97.55	2	242	7	245	5.7e-51	167.7	COG4923	Predicted nuclease (RNAse H fold)	245
2919590776	295	99.3	9	295	1	283	3.3e-92	303.1	COG2301	Citrate lyase beta subunit	283
2919590777	162	87.25	7	162	19	148	7.8e-34	110.8	COG0756	dUTPase	148
2919590778	154	88	12	150	6	137	1.4e-25	84.1	COG1959	DNA-binding transcriptional regulator, IscR family	150
2919590779	138	72.34	5	134	24	125	3.4e-21	70	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2919590780	304	95.07	15	301	13	282	2.0e-83	274.6	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
2919590781	368	99.43	2	356	2	351	9.8e-128	420.5	COG4148	ABC-type molybdate transport system, ATPase component	352
2919590782	230	99.11	4	228	1	223	2.8e-87	286.2	COG4149	ABC-type molybdate transport system, permease component	225
2919590783	262	94.01	1	256	16	266	5.4e-67	220.3	COG0725	ABC-type molybdate transport system, periplasmic component	258
2919590784	612	97.92	1	611	10	575	0.0e+00	771.8	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2919590785	305	81.25	12	298	57	303	2.7e-56	185.7	COG2264	Ribosomal protein L11 methylase PrmA	300
2919590786	612	17.95	18	161	13	82	2.9e-98	12.5	COG0006	Xaa-Pro aminopeptidase	384
2919590786	612	97.95	178	566	7	388	2.9e-98	309.8	COG0006	Xaa-Pro aminopeptidase	384
2919590787	738	65.79	286	724	208	609	8.3e-108	356	COG4232	Thiol:disulfide interchange protein	569
2919590787	738	87.27	16	285	29	268	1.2e-41	137.2	COG4233	Thiol-disulfide interchange protein, contains DsbC and DsbD domains	273
2919590788	387	86.59	15	306	3	241	5.9e-54	177.6	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2919590789	239	96.8	1	230	3	244	2.3e-38	126.3	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
2919590790	306	10.24	246	304	325	363	1.8e-13	3.2	COG3055	N-acetylneuraminic acid mutarotase	381
2919590790	306	11.29	192	252	320	362	1.8e-13	18.1	COG3055	N-acetylneuraminic acid mutarotase	381
2919590790	306	22.57	37	152	69	154	1.8e-13	18.8	COG3055	N-acetylneuraminic acid mutarotase	381
2919590791	438	13.22	16	144	6	65	6.5e-29	47.9	COG1231	Monoamine oxidase	450
2919590791	438	14.1	203	301	227	290	6.5e-29	19.5	COG1231	Monoamine oxidase	450
2919590791	438	20.26	324	435	358	449	6.5e-29	27.7	COG1231	Monoamine oxidase	450
2919590793	144	55.04	1	134	51	121	1.8e-15	51.3	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2919590794	334	99.08	6	331	2	325	2.3e-106	349.7	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2919590795	183	86.55	4	183	23	170	2.9e-52	171.1	COG3807	SH3-like domain	171
2919590796	169	89.66	30	168	6	135	2.7e-31	102.7	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2919590797	244	92.04	18	242	4	211	2.7e-32	106.4	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
2919590798	177	97.3	22	177	2	145	7.0e-41	133.9	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2919590799	408	99.76	1	407	2	414	0.0e+00	454.9	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2919590801	276	98.46	2	264	2	256	8.5e-113	370.3	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
2919590802	497	89.07	64	484	48	438	6.0e-67	220.8	COG3659	Carbohydrate-selective porin OprB	439
2919590803	578	72.13	2	116	15	102	4.1e-48	25	COG1445	Phosphotransferase system fructose-specific component IIB	122
2919590803	578	90.16	118	235	2	111	4.1e-48	129.5	COG1445	Phosphotransferase system fructose-specific component IIB	122
2919590803	578	97.38	244	578	2	336	2.2e-129	425.5	COG1299	Phosphotransferase system, fructose-specific IIC component	343
2919590804	317	99.35	3	316	2	309	1.8e-100	330.2	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
2919590805	850	87.64	161	248	6	83	5.0e-21	67.9	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
2919590805	850	93.66	11	148	8	140	9.5e-42	135.4	COG4668	Mannitol/fructose-specific phosphotransferase system, IIA domain	142
2919590805	850	97.91	276	845	4	565	0.0e+00	609	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
2919590806	327	98.8	3	327	3	332	2.7e-99	327	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2919590807	554	98.16	6	554	7	540	2.9e-123	406.4	COG1178	ABC-type Fe3+ transport system, permease component	540
2919590808	331	99.67	31	330	1	300	1.2e-59	196.6	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2919590809	354	88.67	11	345	5	317	6.2e-95	312.6	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2919590811	719	99.86	2	718	2	734	0.0e+00	776.4	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
2919590815	604	89.04	278	604	18	220	4.6e-49	160.7	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919590816	475	79.95	144	475	73	387	1.8e-49	164	COG0642	Signal transduction histidine kinase	336
2919590817	239	98.28	17	239	2	229	3.2e-67	220.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919590818	185	78.95	29	182	7	111	2.1e-18	60.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919590819	295	98.6	10	292	2	282	6.1e-82	270.1	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2919590821	76	84.48	19	76	7	55	3.9e-10	33.9	COG3847	Flp pilus assembly protein, pilin Flp	58
2919590822	282	14.74	136	227	239	280	9.4e-25	11.3	COG5403	Uncharacterized protein	285
2919590822	282	48.07	1	177	5	141	9.4e-25	71.7	COG5403	Uncharacterized protein	285
2919590823	487	90	34	457	36	449	1.1e-56	186.4	COG0534	Na+-driven multidrug efflux pump	455
2919590824	632	76.23	394	575	19	188	6.2e-25	82.9	COG1226	Voltage-gated potassium channel Kch	212
2919590824	632	98	5	404	5	396	4.9e-90	296.3	COG0475	Kef-type K+ transport system, membrane component KefB	397
2919590826	305	92.13	3	304	25	305	3.3e-106	349.8	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2919590827	222	93.21	7	220	5	210	7.9e-66	216.5	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
2919590828	68	92.42	14	68	1	61	1.2e-24	80.4	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
2919590830	393	97.47	9	391	9	394	2.1e-116	383.5	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2919590831	170	69.33	4	170	63	218	6.6e-37	121.4	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
2919590832	1046	99.9	4	1002	1	1013	0.0e+00	964.1	COG0841	Multidrug efflux pump subunit AcrB	1009
2919590833	406	89.74	4	391	34	383	8.8e-38	124.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919590836	84	31.54	1	75	41	81	2.3e-03	13.7	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2919590841	47	11.47	1	47	7	52	2.3e-20	67.4	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2919590842	434	51.96	223	430	9	207	1.5e-17	16.3	COG0477	MFS family permease	338
2919590842	434	63.71	14	277	14	257	1.5e-17	42.6	COG0477	MFS family permease	338
2919590847	140	57.28	8	140	88	205	1.4e-51	169.9	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
2919590850	289	99.3	1	283	1	284	7.0e-71	233.2	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2919590851	335	96.95	34	335	9	294	2.1e-43	143.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919590852	465	47.52	269	463	8	189	7.3e-38	34.1	COG0477	MFS family permease	338
2919590852	465	83.03	19	300	3	320	7.3e-38	94.3	COG0477	MFS family permease	338
2919590853	265	99.25	3	262	2	267	2.4e-58	192.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919590854	113	46.22	1	113	87	196	2.8e-31	103.6	COG5531	Chromatin remodeling complex protein RSC6, contains SWIB domain	237
2919590856	355	90.5	32	268	13	231	1.9e-14	48.3	COG2202	PAS domain	232
2919590859	423	47.78	26	230	12	194	1.4e-16	15.8	COG0477	MFS family permease	338
2919590859	423	53.26	228	423	5	208	1.4e-16	45.3	COG0477	MFS family permease	338
2919590860	591	98.99	14	585	5	590	0.0e+00	489	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2919590861	502	91.44	29	502	41	478	2.3e-125	413.3	COG4784	Putative Zn-dependent protease	479
2919590867	215	42.69	4	88	6	78	2.0e-07	8.6	COG3652	Predicted outer membrane protein	170
2919590867	215	45.03	118	210	92	168	2.0e-07	15.4	COG3652	Predicted outer membrane protein	170
2919590869	135	63.08	12	130	2	83	1.3e-11	39.9	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2919590870	392	98.97	2	392	3	387	0.0e+00	538.8	COG0192	S-adenosylmethionine synthetase	388
2919590871	236	97.8	12	236	3	224	2.4e-58	191.8	COG0220	tRNA G46 methylase TrmB	227
2919590872	574	95.61	329	569	7	224	1.0e-53	175.7	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919590874	199	99.02	1	199	2	204	3.4e-78	256.7	COG0605	Superoxide dismutase	204
2919590875	509	96.91	1	508	8	509	0.0e+00	454.3	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
2919590876	226	95.67	7	225	5	225	3.5e-40	132.6	COG1011	FMN phosphatase YigB, HAD superfamily	229
2919590878	587	99.64	2	587	2	554	0.0e+00	435.7	COG2192	Predicted carbamoyl transferase, NodU family	555
2919590879	395	98.22	3	389	5	390	0.0e+00	484.6	COG3004	Na+/H+ antiporter NhaA	390
2919590880	216	94.67	60	191	3	144	1.2e-14	48.7	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2919590881	463	99.78	1	460	1	458	0.0e+00	654.9	COG0165	Argininosuccinate lyase	459
2919590884	107	24.54	7	103	185	264	3.6e-05	17.7	COG3547	Transposase	303
2919590885	235	96.83	16	235	3	216	1.4e-51	170	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2919590887	160	91.73	2	139	3	124	5.0e-13	43.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919590888	360	95.18	146	359	2	218	9.5e-49	159.7	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919590889	218	94.25	41	214	5	168	1.5e-63	208.1	COG0225	Peptide methionine sulfoxide reductase MsrA	174
2919590890	167	97.04	1	167	3	166	7.1e-51	166.9	COG2862	Uncharacterized membrane protein YqhA	169
2919590891	314	88.03	12	314	27	276	5.6e-110	361.2	COG3770	Murein endopeptidase	284
2919590893	204	89.14	1	204	22	218	1.4e-85	281.2	COG4318	Uncharacterized protein	221
2919590894	138	95.51	1	138	3	151	7.5e-40	128	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
2919590896	334	99.39	6	332	3	329	1.3e-105	347.7	COG0240	Glycerol-3-phosphate dehydrogenase	329
2919590897	305	93.05	114	300	12	185	1.4e-25	84.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2919590898	346	98.55	1	346	1	339	1.3e-120	396.9	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
2919590900	69	100	1	69	1	69	2.1e-31	102.5	COG3585	Molybdopterin-binding protein	69
2919590901	129	97.27	1	113	3	109	3.3e-23	76.6	COG5586	Uncharacterized protein	110
2919590903	315	82.48	1	306	1	259	2.2e-110	363.3	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
2919590904	205	100	1	205	1	210	1.6e-60	198.8	COG0522	Ribosomal protein S4 or related protein	205
2919590906	283	82.46	12	247	4	224	1.3e-73	241.8	COG0796	Glutamate racemase	269
2919590907	429	25.83	348	429	246	331	6.7e-53	51.1	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2919590907	429	58.26	118	353	6	199	6.7e-53	124	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2919590908	324	94.12	13	323	16	319	9.3e-97	318	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
2919590909	1156	14.77	19	377	35	69	3.2e-05	9.2	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
2919590909	1156	22.78	1021	1121	160	213	3.2e-05	6.2	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
2919590912	379	96.71	5	377	6	358	3.5e-86	283.8	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2919590915	495	10.43	451	495	246	286	7.9e-106	2	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2919590915	495	93.64	2	459	23	390	7.9e-106	347.3	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2919590916	117	67.72	1	115	38	144	3.3e-13	44.4	COG5490	Uncharacterized protein	158
2919590917	113	91.59	11	113	10	107	6.5e-44	142.6	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
2919590918	828	40.75	426	762	470	797	0.0e+00	449.7	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2919590918	828	49.81	3	434	2	402	0.0e+00	523.4	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2919590920	161	82.32	4	158	14	148	9.4e-56	182.2	COG5321	Uncharacterized protein	164
2919590921	173	76.44	2	172	8	166	6.2e-39	127.9	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2919590922	282	97.86	1	282	2	276	2.8e-88	290.1	COG2240	Pyridoxal/pyridoxine/pyridoxamine kinase	281
2919590923	301	99.32	1	301	1	290	4.3e-86	283.5	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
2919590925	110	11.47	1	96	4	42	4.6e-04	14.2	COG4246	Uncharacterized protein	340
2919590926	159	26.75	17	138	8	49	1.3e-04	15.8	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2919590927	237	52.84	19	200	46	194	1.7e-28	93.7	COG0421	Spermidine synthase	282
2919590928	521	99.27	11	421	2	411	0.0e+00	496.3	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2919590934	386	65.52	11	303	11	219	7.1e-16	51.6	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2919590937	154	57.04	3	112	17	93	1.1e-05	19.4	COG1310	Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif	134
2919590938	377	18.68	180	283	267	345	4.2e-38	10.1	COG3673	Uncharacterized protein, PA2063/DUF2235 family	423
2919590938	377	45.15	1	189	30	220	4.2e-38	113.8	COG3673	Uncharacterized protein, PA2063/DUF2235 family	423
2919590939	143	58.13	8	139	84	201	2.3e-27	90.2	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2919590940	429	95.72	4	363	6	363	8.0e-50	164.4	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2919590941	68	85.71	6	68	6	65	2.1e-06	21.8	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2919590944	148	93.59	1	148	8	153	1.0e-56	185.4	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2919590945	744	8.59	193	265	5	68	1.9e-109	26.8	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919590945	744	20.4	43	198	458	609	1.9e-109	76.9	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919590945	744	30.34	260	485	106	331	1.9e-109	69.7	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919590945	744	34.63	479	743	487	744	1.9e-109	198.7	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919590950	165	91.73	6	129	8	129	3.4e-15	50.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919590952	143	89.86	2	141	13	145	5.9e-52	169.9	COG4957	Predicted transcriptional regulator	148
2919590953	435	98.07	1	399	1	407	0.0e+00	566	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
2919590956	57	82.09	1	57	4	58	2.7e-17	57.1	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2919590957	250	75.25	3	229	57	284	8.5e-23	75.8	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2919590960	68	48	1	68	64	123	4.7e-08	28.2	COG3293	Transposase	124
2919590961	133	40.85	2	129	166	281	1.0e-25	85.2	COG2801	Transposase InsO and inactivated derivatives	232
2919590962	343	98.75	1	326	1	316	3.8e-101	332.6	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2919590964	42	13.79	1	34	199	230	1.0e-08	29.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919590965	353	92.83	1	326	4	301	3.1e-22	73.8	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919590966	288	91.85	3	268	3	250	2.5e-77	254	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2919590967	389	98.01	20	388	2	346	8.0e-98	322	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2919590968	126	91.73	1	125	5	126	7.5e-33	107.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919590969	161	89.09	1	155	7	153	4.4e-27	89	COG0835	Chemotaxis signal transduction protein	165
2919590970	918	11.27	651	773	617	701	0.0e+00	28	COG0643	Chemotaxis protein histidine kinase CheA	716
2919590970	918	17.51	1	197	6	137	0.0e+00	71.4	COG0643	Chemotaxis protein histidine kinase CheA	716
2919590970	918	57.29	155	643	316	747	0.0e+00	542.4	COG0643	Chemotaxis protein histidine kinase CheA	716
2919590970	918	89.47	787	918	6	124	4.3e-22	71.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919590971	244	96.26	1	214	6	211	3.8e-77	252.8	COG5385	Uncharacterized protein	214
2919590972	282	94.93	4	266	6	267	7.7e-61	200.1	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
2919590974	204	83.41	7	204	35	205	1.3e-78	257.4	COG5400	Uncharacterized protein	205
2919590975	269	14.04	44	255	317	480	1.7e-04	13.4	COG1196	Chromosome segregation ATPase	1163
2919590977	115	50	4	51	4	32	4.4e-04	14	COG5567	Predicted small periplasmic lipoprotein YifL (function unknown0	58
2919590978	422	99.75	1	394	2	395	0.0e+00	435.2	COG0019	Diaminopimelate decarboxylase	394
2919590979	113	95.5	1	111	2	107	1.7e-36	119.4	COG4226	Predicted nuclease of the RNAse H fold, HicB family	111
2919590980	296	96.99	1	296	4	293	5.1e-76	249.7	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2919590981	349	99.13	6	345	2	341	3.0e-122	402.2	COG2008	Threonine aldolase	342
2919590983	878	39.26	576	637	80	132	5.9e+00	3.7	COG0355	FoF1-type ATP synthase, epsilon subunit	135
2919590983	878	40	474	546	76	129	5.9e+00	7.7	COG0355	FoF1-type ATP synthase, epsilon subunit	135
2919590984	61	13.69	1	61	194	249	4.6e-02	7.1	COG0672	High-affinity Fe2+/Pb2+ permease	383
2919590986	190	98.92	1	190	2	184	3.0e-71	233.2	COG2096	Cob(I)alamin adenosyltransferase	184
2919590987	249	98.85	1	249	1	258	2.0e-93	306.8	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2919590988	315	99.37	1	313	2	317	3.2e-107	353.3	COG2025	Electron transfer flavoprotein, alpha subunit	313
2919590989	293	86.32	3	292	3	286	1.1e-111	367.5	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2919590990	100	24.53	2	93	6	44	1.1e-04	16.5	COG1580	Flagellar basal body-associated protein FliL	159
2919590991	338	99.4	11	336	1	329	4.4e-101	333	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2919590992	213	98.57	5	213	3	209	8.7e-89	291.1	COG0035	Uracil phosphoribosyltransferase	210
2919590994	208	90.91	6	206	14	203	7.5e-21	70.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919590996	406	98.74	1	406	1	392	0.0e+00	493.3	COG1015	Phosphopentomutase	397
2919590997	542	99.63	1	532	2	533	0.0e+00	841.7	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
2919590998	153	25.72	1	153	440	591	6.4e-18	59.1	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
2919590999	958	49.41	468	885	90	381	6.0e-09	26.7	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
2919590999	958	59.44	13	499	142	478	1.7e-22	74.9	COG1404	Serine protease, subtilisin family	508
2919591001	302	80.5	7	294	59	314	9.1e-47	154.4	COG0657	Acetyl esterase/lipase	312
2919591002	252	86.24	7	219	27	214	2.4e-23	77	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919591004	441	86.71	29	440	48	419	4.1e-45	148.7	COG3307	O-antigen ligase	424
2919591005	588	2.98	226	261	429	451	1.3e-74	4.2	COG4993	Glucose dehydrogenase	773
2919591005	588	7.5	401	486	554	611	1.3e-74	8.5	COG4993	Glucose dehydrogenase	773
2919591005	588	11.77	477	588	683	773	1.3e-74	40	COG4993	Glucose dehydrogenase	773
2919591005	588	16.43	265	406	370	496	1.3e-74	115.1	COG4993	Glucose dehydrogenase	773
2919591005	588	19.02	4	196	151	297	1.3e-74	78.5	COG4993	Glucose dehydrogenase	773
2919591006	176	62.12	21	174	81	285	6.1e-23	73.7	COG0666	Ankyrin repeat	235
2919591010	902	98.79	156	818	4	658	0.0e+00	1066.4	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
2919591012	258	60	117	257	51	140	3.1e-32	106.3	COG3753	Uncharacterized conserved protein YidB, DUF937 family	143
2919591013	419	99.28	1	419	2	412	0.0e+00	535.2	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2919591014	78	96.3	1	78	3	80	1.3e-28	93.4	COG0236	Acyl carrier protein	80
2919591015	246	99.25	2	245	2	267	2.1e-78	258	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919591016	316	95	1	314	5	327	2.1e-80	264.6	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
2919591017	137	100	1	72	1	74	1.2e-23	76.8	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
2919591018	746	99.31	1	744	6	724	0.0e+00	849	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2919591019	196	84.73	1	192	4	175	1.2e-37	124.2	COG0461	Orotate phosphoribosyltransferase	201
2919591020	222	95.83	2	184	6	189	3.4e-49	161.9	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
2919591021	189	96.82	20	188	3	154	2.7e-33	109.2	COG1225	Peroxiredoxin	157
2919591022	157	95.42	5	157	5	150	4.6e-60	196.1	COG0691	tmRNA-binding protein	153
2919591023	298	97.99	4	297	3	295	6.6e-112	367.4	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2919591024	767	97.69	458	758	2	297	2.3e-52	173.2	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2919591026	670	11.56	622	658	146	168	4.6e-08	4.7	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2919591026	670	29.65	425	548	80	138	4.6e-08	20.2	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2919591028	605	16.26	4	99	3	89	0.0e+00	70.3	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2919591028	605	74.77	90	498	133	532	0.0e+00	402.7	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2919591031	117	45.16	3	117	70	181	9.5e-47	154.5	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
2919591032	365	93.4	9	289	19	301	1.4e-85	281.4	COG0863	DNA modification methylase	302
2919591034	299	79.23	19	296	27	232	1.2e-37	124	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2919591035	443	91.87	1	439	11	462	2.8e-48	159	COG0531	Amino acid transporter	466
2919591036	589	99.45	1	589	1	545	0.0e+00	464.2	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2919591037	279	98.83	1	259	1	253	5.4e-58	190.9	COG0121	Predicted glutamine amidotransferase	252
2919591039	384	74.22	9	315	22	260	6.4e-18	59.1	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
2919591042	341	89.05	28	341	6	314	7.9e-99	325.2	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2919591045	323	97.83	1	322	1	315	0.0e+00	448.8	COG0435	Glutathionyl-hydroquinone reductase	324
2919591046	765	96.91	4	761	23	807	0.0e+00	434.4	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2919591048	487	98.15	10	481	8	484	0.0e+00	463.3	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
2919591049	693	21.79	390	509	324	445	1.7e-36	44.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919591049	693	21.96	3	156	268	390	1.7e-36	5.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919591049	693	33.57	127	435	277	464	1.7e-36	23.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919591049	693	45.18	418	690	268	520	1.7e-36	82.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919591050	159	24.06	2	159	588	773	8.0e-27	87	COG4993	Glucose dehydrogenase	773
2919591051	415	97.72	20	408	6	391	1.5e-103	340.6	COG2814	Predicted arabinose efflux permease, MFS family	394
2919591053	159	93.98	17	148	3	127	1.6e-17	58.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919591054	216	97.63	4	213	1	206	2.2e-58	191.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919591055	804	60.95	376	751	182	476	6.0e-28	92	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2919591056	337	59.76	187	325	66	163	1.5e-09	32.9	COG2010	Cytochrome c, mono- and diheme variants	150
2919591056	337	66.67	5	192	41	180	5.7e-28	91	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
2919591057	191	91.03	33	164	3	144	2.1e-23	77.7	COG2165	Type II secretory pathway, pseudopilin PulG	149
2919591062	484	97.23	8	484	9	465	2.6e-80	264.5	COG2865	Predicted transcriptional regulator, contains HTH domain	467
2919591070	394	81.06	227	374	21	127	1.1e-16	54.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919591076	43	44.79	1	43	1	43	1.3e-18	61.5	COG0234	Co-chaperonin GroES (HSP10)	96
2919591077	203	83.33	3	203	30	204	6.3e-50	164	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
2919591078	284	89.77	1	282	26	262	7.0e-44	141	COG1237	Metal-dependent hydrolase, beta-lactamase superfamily II	259
2919591079	248	89.24	5	241	3	226	5.9e-74	243	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2919591080	185	35.82	21	159	9	128	2.0e-21	70.9	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919591081	246	37.61	1	187	141	266	2.0e-31	103.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919591082	276	93.02	20	275	11	250	2.8e-57	188.3	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2919591083	185	78.1	40	183	23	129	1.2e-10	33.9	COG1765	Uncharacterized OsmC-related protein	137
2919591084	358	93.98	8	358	16	390	4.6e-17	55.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919591085	217	96.06	1	204	6	200	1.2e-49	163.1	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
2919591086	470	95.61	5	453	10	445	0.0e+00	477.9	COG2233	Xanthine/uracil permease	451
2919591087	183	30.23	42	174	169	259	1.8e-09	31.1	COG3258	Cytochrome c	293
2919591088	406	71.97	2	358	51	258	1.3e-42	140.2	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2919591089	265	72.54	2	265	91	333	4.1e-26	86	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919591092	2340	38.21	203	1557	264	477	4.1e-23	35.7	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919591092	2340	46.96	1578	1898	219	481	4.1e-23	31.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919591094	482	96.6	1	481	4	486	9.9e-87	285.9	COG0591	Na+/proline symporter	493
2919591096	491	91.55	12	481	8	462	5.4e-118	389.2	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
2919591098	371	39.36	23	334	210	370	8.6e-08	26.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919591107	393	67.73	22	330	46	320	4.0e-06	20.4	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
2919591108	474	96.47	1	464	8	472	1.5e-22	73.9	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2919591109	505	82.88	1	495	30	460	0.0e+00	495.9	COG0513	Superfamily II DNA and RNA helicase	513
2919591110	61	91.53	1	57	3	56	1.1e-20	67.6	COG3422	Uncharacterized conserved protein YegP, UPF0339 family	59
2919591113	150	85.99	4	150	5	139	3.1e-52	170.7	COG1607	Acyl-CoA hydrolase	157
2919591114	175	84.26	1	173	25	190	3.3e-73	239.7	COG0529	Adenylylsulfate kinase or related kinase	197
2919591116	344	91.67	1	331	14	332	6.7e-97	318.9	COG3191	L-aminopeptidase/D-esterase	348
2919591119	112	52.88	20	101	46	100	2.1e-17	57.4	COG2944	DNA-binding transcriptional regulator YiaG, XRE-type HTH domain	104
2919591122	791	73.35	91	509	104	392	3.5e-73	241.9	COG0642	Signal transduction histidine kinase	336
2919591122	791	79.7	646	771	7	112	5.5e-55	88.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919591122	791	89.47	525	649	7	125	5.5e-55	91.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919591123	290	96.27	1	288	10	293	2.4e-85	280.8	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
2919591126	401	98.74	7	392	5	396	1.9e-108	357.1	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2919591127	201	20.09	145	201	172	214	4.4e-12	2.2	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
2919591127	201	34.58	13	128	50	123	4.4e-12	36.4	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
2919591128	112	80.53	6	109	18	108	3.3e-31	101.8	COG3952	Uncharacterized N-terminal domain of lipid-A-disaccharide synthase	113
2919591129	255	61.84	5	238	3	224	1.8e-25	85.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2919591130	572	87.57	27	531	11	489	2.8e-56	185.7	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
2919591131	231	55.69	1	214	8	188	1.9e-35	116.8	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2919591132	553	97.18	23	553	9	560	6.7e-107	352.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919591138	359	80	277	353	9	72	4.1e-07	23.3	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2919591139	120	88.72	2	118	6	123	5.2e-20	65.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919591140	424	80.46	8	404	75	391	2.2e-47	156.9	COG0642	Signal transduction histidine kinase	336
2919591142	263	40.39	14	261	5	149	3.0e-17	58.1	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2919591145	280	51.23	5	276	237	486	5.2e-61	201.4	COG3956	Uncharacterized conserved protein YabN, contains tetrapyrrole methylase and MazG-like pyrophosphatase domain	488
2919591147	172	89.31	16	146	5	121	5.1e-23	76.1	COG4270	Uncharacterized membrane protein	131
2919591148	280	96.49	1	274	4	278	4.8e-51	168.5	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2919591149	213	97.91	1	189	3	189	2.0e-72	237.1	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
2919591150	460	92.72	8	460	28	460	0.0e+00	446.5	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2919591151	451	99.09	17	451	3	439	0.0e+00	443.4	COG0621	tRNA A37 methylthiotransferase MiaB	437
2919591153	185	78.16	1	179	36	196	8.0e-42	137.7	COG1335	Nicotinamidase-related amidase	205
2919591154	285	96.35	4	285	1	290	4.3e-46	152.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919591155	141	76.81	68	128	5	57	4.7e-18	17.3	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2919591155	141	95.65	1	69	1	66	4.7e-18	40.4	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2919591157	317	18.75	16	152	30	53	6.7e-05	16.4	COG1708	Predicted nucleotidyltransferase	128
2919591158	352	36.53	22	327	18	173	1.2e-28	94.8	COG1078	HD superfamily phosphohydrolase	421
2919591159	323	100	1	323	1	331	2.8e-102	336.9	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2919591160	414	97.71	16	398	4	387	8.7e-80	263.2	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2919591162	1197	98.95	28	1191	10	1137	0.0e+00	1295	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
2919591163	98	95.74	1	95	2	91	2.6e-29	95.4	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
2919591164	714	97.2	11	702	7	665	0.0e+00	765.9	COG1200	RecG-like helicase	677
2919591166	256	91.44	25	254	4	206	4.2e-69	226.7	COG2928	Uncharacterized membrane protein	222
2919591167	60	8.29	2	60	565	615	6.9e-19	62.1	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
2919591169	256	98.3	1	252	2	232	1.9e-45	149.6	COG2243	Precorrin-2 methylase	234
2919591170	545	81.31	1	426	36	431	2.8e-73	241.8	COG1061	Superfamily II DNA or RNA helicase	442
2919591171	139	84.96	12	133	16	128	1.4e-25	84.4	COG2346	Truncated hemoglobin YjbI	133
2919591174	1057	99.03	10	1038	4	1023	0.0e+00	847.5	COG3696	Cu/Ag efflux pump CusA	1027
2919591176	395	96.05	179	395	5	223	1.3e-56	185.3	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919591177	162	98.72	2	158	2	155	1.4e-65	214	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2919591178	366	98.25	1	331	3	283	1.0e-90	298.6	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2919591179	742	98.79	6	742	5	740	0.0e+00	574	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919591181	235	94.71	1	207	5	201	2.4e-58	191.7	COG0288	Carbonic anhydrase	207
2919591182	515	92.01	1	515	17	534	2.4e-109	360.6	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2919591183	438	83.68	270	437	26	184	5.7e-18	57.8	COG2320	GrpB domain, predicted nucleotidyltransferase, UPF0157 family	185
2919591183	438	99.23	1	261	2	259	2.4e-95	313.3	COG3622	Hydroxypyruvate isomerase	260
2919591184	473	94.17	37	463	16	403	0.0e+00	459.1	COG2262	50S ribosomal subunit-associated GTPase HflX	411
2919591185	83	96.1	3	79	3	76	5.2e-38	123	COG1923	sRNA-binding regulator protein Hfq	77
2919591186	456	97.86	1	456	3	459	0.0e+00	523.4	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2919591187	782	98.03	31	742	10	707	0.0e+00	701.9	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
2919591188	267	96.34	1	267	3	265	5.6e-55	180.9	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2919591189	260	99.22	1	256	2	256	3.8e-77	253.4	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
2919591190	527	97.32	9	526	4	547	0.0e+00	607.8	COG0143	Methionyl-tRNA synthetase	558
2919591191	353	43.93	13	291	10	266	4.6e-26	84.7	COG2812	DNA polymerase III, gamma/tau subunits	515
2919591192	241	97.6	14	224	3	205	4.1e-67	220.1	COG0125	Thymidylate kinase	208
2919591193	398	94.15	1	387	16	385	4.7e-113	372.7	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2919591194	426	74.19	15	259	10	193	1.8e-62	205.6	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
2919591196	212	21.21	1	73	2	57	1.1e-28	46.5	COG1192	Cellulose biosynthesis protein BcsQ	259
2919591196	212	53.79	59	208	121	262	1.1e-28	47.6	COG1192	Cellulose biosynthesis protein BcsQ	259
2919591198	488	97.86	1	488	5	461	0.0e+00	567.2	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2919591199	384	96.69	14	379	7	357	4.4e-129	424.7	COG3852	Signal transduction histidine kinase, nitrogen specific	363
2919591200	345	87.38	13	329	9	292	1.6e-97	320.9	COG0042	tRNA-dihydrouridine synthase	323
2919591201	426	95.69	1	239	5	226	6.0e-57	186.7	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
2919591201	426	96.86	251	409	2	155	3.7e-61	199.8	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
2919591202	167	93.25	4	165	10	161	2.3e-57	187.3	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
2919591203	461	92.13	16	451	28	437	4.2e-75	247.3	COG0038	H+/Cl- antiporter ClcA	443
2919591204	59	94.44	3	58	1	51	5.7e-15	49.2	COG5487	Uncharacterized membrane protein YtjA, UPF0391 family	54
2919591205	287	79.48	2	279	2	214	2.1e-45	149.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919591206	91	96.77	1	91	2	91	1.1e-20	68	COG2929	Uncharacterized conserved protein, DUF497 family	93
2919591207	106	89.47	15	104	7	91	1.9e-21	71	COG3514	Uncharacterized conserved protein, DUF4415 family	93
2919591208	569	99.62	18	550	2	520	0.0e+00	490.4	COG1384	Lysyl-tRNA synthetase, class I	521
2919591209	309	93.99	21	308	8	273	1.4e-38	126.9	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2919591210	622	53.86	201	587	53	324	3.3e-44	145.7	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2919591211	197	88.1	5	197	18	202	3.2e-52	171.5	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
2919591212	486	95.26	18	229	3	203	2.2e-44	145	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
2919591212	486	95.49	230	483	3	235	3.3e-82	269.7	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2919591213	894	84.13	838	894	3	55	7.7e-09	29.3	COG2906	Bacterioferritin-associated ferredoxin	63
2919591213	894	94.81	1	713	42	809	0.0e+00	558.3	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2919591214	534	62.98	137	534	222	597	2.0e-114	377.3	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
2919591215	596	97.86	59	589	9	511	2.4e-113	373.5	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2919591216	416	49.56	11	416	3	399	0.0e+00	438.6	COG1251	NAD(P)H-nitrite reductase, large subunit	793
2919591217	70	15.42	4	69	86	122	1.2e-03	12.7	COG5343	Anti-sigma-K factor RskA	240
2919591218	340	88.66	2	315	34	330	5.5e-48	157.8	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919591219	195	97.94	1	194	4	193	1.1e-62	205.4	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
2919591221	626	96.96	1	594	16	620	8.0e-124	409	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
2919591222	691	99.25	12	687	5	662	0.0e+00	863.4	COG0021	Transketolase	663
2919591223	950	13.69	693	785	379	440	1.3e-46	25.2	COG0166	Glucose-6-phosphate isomerase	446
2919591223	950	52.76	365	680	61	299	1.3e-46	126.3	COG0166	Glucose-6-phosphate isomerase	446
2919591223	950	98.68	10	370	3	302	2.6e-74	244.6	COG0176	Transaldolase	239
2919591224	324	98.67	1	324	1	296	0.0e+00	446.8	COG1023	6-phosphogluconate dehydrogenase (decarboxylating)	300
2919591225	247	97.5	8	246	4	237	1.1e-48	160	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
2919591227	381	84.32	27	196	2	157	2.2e-56	51.3	COG0717	Deoxycytidine triphosphate deaminase	183
2919591227	381	97.84	162	381	2	182	2.2e-56	139.4	COG0717	Deoxycytidine triphosphate deaminase	183
2919591229	130	98.41	2	127	2	125	2.2e-50	164.3	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
2919591230	392	96.41	4	390	15	417	1.1e-77	256.2	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2919591231	190	94.65	7	178	11	187	1.8e-42	139.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2919591233	331	98.95	11	326	3	286	8.5e-91	298.5	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
2919591234	327	98.07	18	323	6	310	1.6e-114	376.7	COG0078	Ornithine carbamoyltransferase	310
2919591235	401	95.06	1	392	16	400	0.0e+00	497.6	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2919591236	157	93.38	7	157	8	134	5.4e-22	72.5	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2919591237	250	91.51	4	248	9	256	3.0e-33	109.6	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2919591238	412	98.71	7	402	5	386	0.0e+00	571.9	COG3146	Predicted N-acyltransferase	387
2919591239	386	97.71	1	386	6	389	2.8e-130	429.3	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2919591240	171	98.77	1	162	2	161	1.4e-67	220.4	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
2919591241	325	94.1	2	323	12	298	1.5e-57	189.1	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2919591242	152	97.87	14	150	2	139	1.6e-39	129.4	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2919591245	684	95.32	16	309	4	268	1.6e-46	152.6	COG0388	Predicted amidohydrolase	274
2919591245	684	99.27	340	660	2	273	2.7e-81	267.1	COG0171	NH3-dependent NAD+ synthetase	268
2919591251	370	55.17	2	309	14	189	4.1e-10	32.6	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2919591253	104	47.69	4	100	2	63	1.5e-08	30.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2919591254	1243	98.69	24	988	3	755	0.0e+00	557.9	COG0209	Ribonucleotide reductase alpha subunit	696
2919591255	138	100	11	137	1	118	1.0e-42	139.7	COG3761	NADH:ubiquinone oxidoreductase 17.2 kD subunit	118
2919591256	222	67.68	7	144	49	159	3.9e-50	164.1	COG4765	Uncharacterized protein	164
2919591257	339	47.83	263	319	5	37	1.4e-04	15.2	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2919591258	227	84.62	3	209	22	208	2.3e-73	239.9	COG2360	Leu/Phe-tRNA-protein transferase	221
2919591260	450	67.96	1	445	1	439	0.0e+00	657.7	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2919591261	160	98.64	12	160	2	146	1.1e-37	124.5	COG0511	Biotin carboxyl carrier protein	140
2919591262	154	96.58	2	146	2	142	7.1e-60	195.1	COG0757	3-dehydroquinate dehydratase	146
2919591263	258	95.58	1	252	11	248	5.0e-39	128.8	COG1651	Protein-disulfide isomerase	244
2919591264	102	57.04	5	102	37	113	1.8e-12	40.8	COG2863	Cytochrome c553	121
2919591265	415	8.37	11	60	144	179	2.8e-27	23.4	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2919591265	415	79.3	28	405	1	341	2.8e-27	80	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2919591266	385	97.47	6	385	5	390	8.1e-97	319.1	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2919591267	415	17.07	65	356	606	767	4.1e-04	12.7	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2919591268	955	99.39	3	695	2	487	0.0e+00	758.9	COG1530	Ribonuclease G or E	487
2919591269	121	28.44	27	75	62	92	9.9e+00	3.4	COG2058	Ribosomal protein L12E/L44/L45/RPP1/RPP2	109
2919591269	121	42.2	63	117	44	89	9.9e+00	3.4	COG2058	Ribosomal protein L12E/L44/L45/RPP1/RPP2	109
2919591270	340	97.81	19	339	7	318	5.5e-109	358.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919591272	501	98.81	2	501	2	499	0.0e+00	643.5	COG3333	TctA family transporter	504
2919591273	331	96.55	5	328	8	315	5.2e-84	276.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919591274	222	87.04	1	222	33	247	1.0e-92	304.2	COG5530	Uncharacterized membrane protein	247
2919591275	246	77.54	5	243	8	228	2.2e-29	96.9	COG2301	Citrate lyase beta subunit	283
2919591276	818	66.99	331	803	106	379	3.3e-11	37.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919591277	231	91.38	2	226	18	229	3.0e-54	178.3	COG1802	DNA-binding transcriptional regulator, GntR family	230
2919591278	420	49.35	209	416	7	195	5.8e-35	40.7	COG0477	MFS family permease	338
2919591278	420	51.17	1	214	4	199	5.8e-35	81.3	COG0477	MFS family permease	338
2919591279	471	99.58	1	470	2	477	0.0e+00	536.7	COG0469	Pyruvate kinase	477
2919591280	212	54.31	10	184	79	204	1.0e-12	42.8	COG0671	Membrane-associated phospholipid phosphatase	232
2919591282	76	12.08	4	63	13	48	5.0e-06	20.3	COG2842	Bacteriophage DNA transposition protein, AAA+ family ATPase	297
2919591283	126	88.24	1	126	12	131	9.9e-44	143.1	COG3474	Cytochrome c2	135
2919591285	284	99.17	42	282	2	241	8.9e-113	369.7	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2919591286	230	90.35	4	230	21	226	5.8e-66	216.7	COG0765	ABC-type amino acid transport system, permease component	222
2919591287	240	92.11	4	238	17	226	2.1e-65	214.9	COG0765	ABC-type amino acid transport system, permease component	222
2919591288	303	95.41	1	280	8	277	9.3e-51	167.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2919591290	427	94.74	2	421	8	403	0.0e+00	436.2	COG1301	Na+/H+-dicarboxylate symporter	415
2919591291	299	92.23	1	277	12	272	3.8e-50	165.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2919591293	1056	99.9	1	1034	1	1013	0.0e+00	1067.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2919591294	406	97.44	14	392	6	385	7.8e-63	207.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919591296	452	96.27	1	315	7	316	4.9e-14	41.9	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
2919591297	266	80.3	7	265	36	247	3.1e-34	112.8	COG3900	Predicted periplasmic protein	262
2919591301	429	49.61	230	426	5	194	9.9e-30	19	COG0477	MFS family permease	338
2919591301	429	71.54	7	257	6	279	9.9e-30	84.7	COG0477	MFS family permease	338
2919591302	391	94.93	87	388	14	331	7.1e-36	118.5	COG0582	Integrase	309
2919591308	34	12.44	3	31	11	35	7.7e-03	10.7	COG4795	Type II secretory pathway, component PulJ	194
2919591313	157	91.89	1	149	6	141	2.9e-52	170.9	COG4957	Predicted transcriptional regulator	148
2919591314	77	27.65	1	75	97	143	2.1e-10	35.2	COG0262	Dihydrofolate reductase	167
2919591315	127	86.61	2	126	14	123	1.6e-06	19.5	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2919591316	540	56.88	6	165	11	134	8.2e-16	51.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919591316	540	98.7	223	540	2	304	4.4e-70	230.4	COG0492	Thioredoxin reductase	305
2919591317	125	82.43	1	125	21	142	5.1e-45	147.5	COG4957	Predicted transcriptional regulator	148
2919591319	311	66.15	155	308	61	189	1.9e-12	41	COG3861	Stress response protein YsnF (function unknown)	195
2919591320	178	59.49	34	175	66	181	3.3e-10	32.2	COG3861	Stress response protein YsnF (function unknown)	195
2919591322	136	84.21	13	134	6	117	2.0e-15	51.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919591323	157	96.99	13	142	3	131	1.7e-20	67.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919591327	62	28.37	7	59	98	137	1.2e-03	13	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2919591331	385	98.49	1	385	6	396	0.0e+00	442.7	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2919591332	247	95.81	64	246	3	185	3.1e-42	139.1	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
2919591333	83	57.66	2	83	14	92	1.3e-09	32.7	COG4319	Ketosteroid isomerase homolog	137
2919591334	379	97.91	6	372	5	378	0.0e+00	463.2	COG3448	CBS-domain-containing membrane protein	382
2919591336	47	11.47	1	47	7	52	2.3e-20	67.4	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2919591338	275	94.07	1	272	15	236	3.6e-19	62	COG3637	Opacity protein and related surface antigens	199
2919591339	303	85.9	1	285	42	303	3.8e-48	158.8	COG4313	Uncharacterized conserved protein	304
2919591344	568	92.21	55	532	4	453	7.6e-91	300.1	COG3119	Arylsulfatase A or related enzyme	475
2919591345	326	79.58	6	322	66	330	2.6e-84	277.6	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2919591346	443	48.56	238	439	12	197	3.2e-14	17.2	COG0477	MFS family permease	338
2919591346	443	66.84	11	274	10	265	3.2e-14	34.5	COG0477	MFS family permease	338
2919591347	429	81.23	11	372	57	359	1.9e-63	208.7	COG4850	Phosphatidate phosphatase APP1	373
2919591349	209	97.39	3	207	3	226	7.4e-68	218.2	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
2919591351	59	12.2	4	59	153	202	1.3e-03	11.7	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2919591355	89	48.46	4	86	3	65	2.8e-11	38.9	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2919591356	296	98.01	5	295	2	296	5.7e-58	191.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919591357	415	47.78	211	409	8	190	2.6e-12	19.6	COG0477	MFS family permease	338
2919591357	415	53	19	231	8	210	2.6e-12	26.2	COG0477	MFS family permease	338
2919591358	249	91.53	5	249	23	292	2.9e-14	47.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919591361	250	85.14	1	236	1	235	2.5e-40	133	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2919591364	328	98.29	5	315	5	291	1.1e-88	291.7	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2919591365	296	79.18	3	289	65	334	1.8e-92	304.7	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2919591367	430	99.77	1	429	1	429	0.0e+00	600.4	COG0104	Adenylosuccinate synthase	430
2919591369	283	97.19	2	282	3	279	1.9e-72	238.9	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2919591371	416	98.6	92	374	4	285	2.9e-99	326.1	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2919591372	436	99.54	1	434	1	437	0.0e+00	551.4	COG0015	Adenylosuccinate lyase	438
2919591374	127	93.98	4	127	3	127	2.6e-15	50.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919591378	151	45.05	19	136	9	90	9.3e-06	20	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2919591379	445	95.9	1	393	12	409	0.0e+00	575.3	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
2919591381	708	92.8	4	708	47	742	5.9e-113	372.6	COG4774	Outer membrane receptor for monomeric catechols	750
2919591382	248	95.26	1	248	4	244	7.7e-95	311.6	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
2919591383	161	78.41	15	161	18	155	5.3e-20	66.2	COG1714	Uncharacterized membrane protein YckC, RDD family	172
2919591386	356	98.18	27	355	5	328	0.0e+00	488.7	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
2919591387	353	98.11	4	325	6	265	3.1e-72	237	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919591389	170	70.68	26	160	5	98	1.1e-15	52.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919591393	456	94.71	3	455	22	451	0.0e+00	462.6	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
2919591394	232	95.73	7	217	3	204	2.3e-73	240.5	COG2518	Protein-L-isoaspartate O-methyltransferase	209
2919591396	1041	74.11	365	741	98	389	9.8e-76	250.3	COG0642	Signal transduction histidine kinase	336
2919591396	1041	90.98	754	881	7	127	1.5e-29	95.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919591397	216	94.31	6	213	4	202	2.8e-50	165.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919591398	207	91.39	5	207	13	203	4.3e-25	84	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919591399	1044	99.9	5	1019	1	1013	0.0e+00	910.6	COG0841	Multidrug efflux pump subunit AcrB	1009
2919591400	363	91.79	2	361	14	371	8.1e-42	137.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919591402	190	96.5	1	187	5	197	1.3e-63	208.3	COG2094	3-methyladenine DNA glycosylase Mpg	200
2919591405	396	84.84	162	396	22	228	5.6e-40	131.8	COG2114	Adenylate cyclase, class 3	227
2919591406	635	98.88	9	635	6	621	0.0e+00	745.1	COG3211	Secreted phosphatase, PhoX family	616
2919591407	416	93.85	8	414	10	375	2.5e-41	136.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919591408	1055	99.71	1	1039	2	1028	0.0e+00	981.2	COG3696	Cu/Ag efflux pump CusA	1027
2919591410	2967	22.86	1108	1437	310	437	1.2e-15	7.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919591410	2967	30.54	758	1109	271	441	1.2e-15	52	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919591412	130	26.53	1	125	348	473	6.1e-47	154.9	COG5361	Uncharacterized conserved protein	458
2919591420	182	93.53	5	178	4	162	5.5e-32	105.4	COG1795	Formaldehyde-activating enzyme nesessary for methanogenesis	170
2919591425	242	77.52	1	205	40	208	1.2e-19	64.8	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919591426	247	95.87	10	226	4	212	3.5e-25	83.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919591428	316	98.01	16	312	4	298	9.1e-48	158	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919591430	153	69.67	1	149	16	162	2.0e-26	87.7	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
2919591431	138	67.3	3	138	22	163	4.1e-26	86.6	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
2919591433	281	88.27	82	276	6	178	5.6e-73	238.2	COG1045	Serine acetyltransferase	194
2919591434	463	50.92	78	281	2	112	1.6e-09	31.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919591435	683	98.29	280	683	3	404	0.0e+00	521.4	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
2919591446	273	83.02	3	263	53	321	3.5e-43	142.5	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2919591448	131	89.47	5	129	6	124	3.2e-08	27.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919591450	197	92.76	1	186	13	217	9.8e-14	43.4	COG2755	Lysophospholipase L1 or related esterase	216
2919591452	127	35.04	8	124	176	271	1.3e-13	46.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2919591453	133	43.95	8	133	71	179	7.6e-53	174.6	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
2919591454	60	19.12	1	43	14	52	3.6e-04	14.4	COG3056	Uncharacterized lipoprotein YajG	204
2919591459	658	96.33	5	624	13	615	0.0e+00	640	COG1297	Uncharacterized membrane protein, oligopeptide transporter (OPT) family	624
2919591460	174	65.91	1	173	69	242	4.0e-52	171.6	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
2919591461	251	82.88	6	234	34	246	3.0e-35	116.2	COG3403	Uncharacterized protein YcgG, contains conserved FPC and CPF motifs	257
2919591462	323	48.75	99	320	45	180	1.1e-09	33.1	COG0500	SAM-dependent methyltransferase	257
2919591463	311	93.5	3	311	19	320	2.4e-72	238.1	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
2919591466	217	94.79	7	217	4	203	3.2e-48	158.6	COG2518	Protein-L-isoaspartate O-methyltransferase	209
2919591467	463	94.35	4	441	19	452	5.2e-81	267.3	COG1538	Outer membrane protein TolC	457
2919591468	204	58.55	36	204	96	232	5.9e-35	102.2	COG3827	Cell pole-organizing protein PopZ	231
2919591469	906	99.77	2	904	2	882	0.0e+00	1160.4	COG0525	Valyl-tRNA synthetase	877
2919591470	104	97.17	1	104	2	104	1.4e-36	119.8	COG2076	Multidrug transporter EmrE and related cation transporters	106
2919591471	804	74.06	150	803	151	641	1.2e-122	404.9	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919591472	519	24.38	417	518	270	358	3.7e-125	36.2	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2919591472	519	96.99	11	414	10	363	3.7e-125	382.1	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2919591473	303	95.31	17	300	9	313	3.1e-72	230.8	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2919591476	289	96.77	14	289	4	273	1.8e-130	428.4	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
2919591478	156	88.59	4	150	15	146	2.2e-52	171.2	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
2919591479	429	99.53	1	426	1	423	0.0e+00	672.3	COG0148	Enolase	423
2919591480	92	66.95	3	90	31	109	7.4e-12	39.6	COG2919	Cell division protein FtsB	117
2919591481	361	90.78	20	361	20	344	4.6e-129	424.7	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
2919591482	483	99.38	160	483	2	323	0.0e+00	472.5	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
2919591484	474	99.77	1	474	1	433	0.0e+00	456.2	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2919591485	479	99.34	1	469	3	454	0.0e+00	557.9	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2919591486	109	31.4	1	105	131	206	1.2e-07	26.6	COG2202	PAS domain	232
2919591496	217	91.67	2	216	18	226	3.7e-53	175.3	COG4291	Uncharacterized membrane protein	228
2919591498	256	72.37	24	237	48	233	9.9e-18	58.8	COG3591	V8-like Glu-specific endopeptidase	251
2919591500	186	25.51	5	69	113	175	4.8e-31	55	COG3773	Cell wall hydrolase CwlJ, involved in spore germination	249
2919591500	186	46.96	59	178	34	149	4.8e-31	55.6	COG3773	Cell wall hydrolase CwlJ, involved in spore germination	249
2919591502	171	45.45	80	153	8	47	3.0e-04	14.9	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2919591503	96	97.56	14	93	1	80	1.9e-19	64	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
2919591504	326	96.73	15	319	9	304	0.0e+00	452.7	COG0320	Lipoate synthase	306
2919591505	153	99.32	1	152	1	145	2.3e-52	171.1	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
2919591506	408	97.96	4	394	2	386	9.1e-67	220.6	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2919591507	742	23.14	102	223	79	134	2.2e-07	12.3	COG2202	PAS domain	232
2919591507	742	35.12	3	126	91	175	2.2e-07	19	COG2202	PAS domain	232
2919591507	742	70.56	208	605	114	391	1.6e-53	177.5	COG0642	Signal transduction histidine kinase	336
2919591507	742	92.48	617	742	6	128	3.5e-20	65.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919591508	364	96.3	1	364	13	376	1.1e-101	335.3	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2919591509	123	91.91	1	118	10	134	8.3e-31	101.3	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2919591510	89	96.34	2	85	2	80	8.8e-23	74.9	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
2919591511	73	25.81	10	73	7	62	1.9e-03	12.3	COG5637	Uncharacterized membrane protein	217
2919591512	212	95.35	5	206	4	208	3.7e-43	142.2	COG0625	Glutathione S-transferase	211
2919591513	733	99.71	1	695	2	693	0.0e+00	1053.3	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
2919591514	91	100	3	91	1	89	1.1e-37	122.5	COG0184	Ribosomal protein S15P/S13E	89
2919591515	497	92.68	20	489	9	464	4.3e-91	300.3	COG0531	Amino acid transporter	466
2919591517	269	98.84	3	269	3	258	9.3e-69	226.1	COG0708	Exonuclease III	261
2919591518	309	86.85	103	302	20	204	1.7e-22	74.1	COG2834	Outer membrane lipoprotein-sorting protein	211
2919591519	151	11.59	1	141	819	926	2.2e-35	116.8	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2919591520	36	14.22	1	36	195	227	9.2e-06	20	COG1802	DNA-binding transcriptional regulator, GntR family	230
2919591521	301	87.19	72	301	29	239	1.9e-55	183	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2919591523	488	76.71	110	486	98	423	1.6e-50	166.7	COG0840	Methyl-accepting chemotaxis protein	408
2919591524	100	34.12	9	100	53	124	1.4e-03	12.9	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919591525	417	95.71	2	408	6	407	3.2e-91	300.6	COG2223	Nitrate/nitrite transporter NarK	417
2919591526	413	67.94	219	404	18	159	9.4e-35	53.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919591526	413	94.74	3	218	6	203	9.4e-35	60.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919591527	607	25.53	483	605	188	271	1.1e-26	31.5	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2919591527	607	40.12	351	485	102	233	1.1e-26	54.4	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2919591527	607	92.45	9	284	10	254	4.5e-63	207.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919591528	60	61.02	10	56	5	40	1.9e-07	25.3	COG3422	Uncharacterized conserved protein YegP, UPF0339 family	59
2919591529	409	99.25	3	404	4	401	0.0e+00	471.7	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2919591530	266	98.49	6	263	5	265	8.5e-66	216.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919591531	450	99.21	52	447	2	377	4.2e-99	326	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2919591532	229	84.18	26	189	6	154	1.4e-29	97.1	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2919591533	340	97.59	3	340	6	329	3.2e-49	162.5	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2919591534	218	90.52	1	213	16	225	3.3e-57	188.1	COG1802	DNA-binding transcriptional regulator, GntR family	230
2919591535	225	90.09	6	224	14	222	3.4e-52	171.6	COG1802	DNA-binding transcriptional regulator, GntR family	230
2919591536	982	98	559	979	6	398	2.1e-53	176	COG0247	Fe-S oxidoreductase	388
2919591536	982	98.29	20	530	8	468	3.2e-89	294.6	COG0277	FAD/FMN-containing dehydrogenase	459
2919591537	349	99.13	2	342	2	341	1.5e-81	268.6	COG2008	Threonine aldolase	342
2919591539	498	98.79	1	496	6	496	0.0e+00	547.9	COG2317	Zn-dependent carboxypeptidase, M32 family	497
2919591541	140	90.28	1	140	12	141	4.7e-40	131.2	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
2919591542	347	87.72	127	328	3	202	3.3e-28	92.6	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919591545	437	96.89	15	437	14	418	0.0e+00	555.8	COG5323	Large terminase phage packaging protein	410
2919591546	387	89.38	19	387	28	389	1.6e-98	324.4	COG4695	Phage portal protein BeeE	398
2919591547	178	78.87	1	152	25	177	7.8e-34	111.3	COG3740	Phage head maturation protease	194
2919591548	423	95.5	1	423	16	418	0.0e+00	458.7	COG4653	Predicted phage phi-C31 gp36 major capsid-like protein	422
2919591557	123	89.91	14	121	9	106	2.1e-09	31.9	COG5614	Bacteriophage head-tail adaptor	109
2919591559	136	98.55	1	136	1	136	1.9e-52	171.3	COG5437	Predicted secreted protein	138
2919591561	192	19.78	7	192	706	883	6.7e-28	91.7	COG5281	Phage-related minor tail protein	833
2919591562	213	99.46	28	213	1	183	1.0e-68	225.1	COG5448	Uncharacterized protein	184
2919591563	303	95.85	1	291	1	277	2.8e-90	297.4	COG5449	Uncharacterized protein	225
2919591564	153	47.39	2	140	131	248	3.1e-20	67.9	COG0791	Cell wall-associated hydrolase, NlpC family	197
2919591568	208	90.13	1	143	13	149	4.1e-36	118.4	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
2919591572	125	40.69	23	124	81	139	5.4e-05	18.4	COG3212	Uncharacterized membrane protein YkoI	144
2919591573	225	98.71	1	220	2	230	2.1e-81	267.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919591574	183	56.12	3	167	17	126	4.4e-11	37.5	COG4961	Flp pilus assembly protein TadG	185
2919591575	172	36.21	23	69	4	24	2.5e-03	11.6	COG3847	Flp pilus assembly protein, pilin Flp	58
2919591577	650	45.87	7	131	130	240	5.3e-43	43.9	COG2202	PAS domain	232
2919591577	650	46.69	129	253	129	241	5.3e-43	60.4	COG2202	PAS domain	232
2919591577	650	47.52	258	375	127	241	5.3e-43	42.1	COG2202	PAS domain	232
2919591578	472	89.34	101	470	41	392	1.1e-35	118.5	COG0642	Signal transduction histidine kinase	336
2919591579	499	15.22	287	357	142	185	5.7e-62	13	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
2919591579	499	20.07	391	477	127	184	5.7e-62	3.6	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
2919591579	499	97.92	2	291	3	285	5.7e-62	196.4	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
2919591580	166	96.08	1	154	4	150	3.0e-54	177.2	COG2332	Cytochrome c-type biogenesis protein CcmE	153
2919591581	667	98.92	1	658	3	641	0.0e+00	774.2	COG1138	Cytochrome c biogenesis factor	648
2919591582	158	95.42	6	158	7	152	5.2e-49	160	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
2919591584	226	93.52	6	225	15	216	1.1e-35	117.8	COG3683	ABC-type uncharacterized transport system, periplasmic component	213
2919591585	338	91.37	53	334	25	310	3.7e-54	178.8	COG2215	ABC-type nickel/cobalt efflux system, permease component RcnA	303
2919591588	196	76.56	3	190	3	162	3.6e-26	86.7	COG0406	Broad specificity phosphatase PhoE	208
2919591589	178	85.44	1	177	27	202	2.4e-30	100.4	COG1335	Nicotinamidase-related amidase	205
2919591590	1199	41.77	709	752	28	60	2.3e-01	4.1	COG3074	Cell division protein ZapB, interacts with FtsZ	79
2919591590	1199	55.7	657	716	21	64	2.3e-01	6.1	COG3074	Cell division protein ZapB, interacts with FtsZ	79
2919591590	1199	95.18	845	1182	8	224	5.1e-43	140.5	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919591590	1199	98.15	227	492	3	267	8.5e-78	255	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2919591591	133	52.59	13	133	2	123	8.0e-10	32.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919591592	252	73.85	27	233	49	209	6.0e-15	49.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919591593	131	96.58	2	125	5	145	3.6e-15	52.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919591594	322	98.33	13	321	5	298	2.6e-71	234.8	COG4973	Site-specific recombinase XerC	299
2919591595	290	89.47	11	140	6	124	6.9e-17	27.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919591595	290	92.48	135	263	6	128	6.9e-17	27.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919591596	468	99.56	1	458	3	455	0.0e+00	563.3	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2919591597	433	99.77	1	432	1	433	0.0e+00	507.3	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2919591598	100	72.83	2	96	13	79	4.6e-05	18.5	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
2919591599	994	99.57	7	994	4	922	0.0e+00	1382.5	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
2919591600	89	29.25	1	89	206	291	2.9e-29	96.8	COG0074	Succinyl-CoA synthetase, alpha subunit	293
2919591601	42	13.79	1	34	199	230	1.7e-08	28.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919591604	241	86.21	2	234	31	255	1.8e-56	185.7	COG5429	Uncharacterized protein	261
2919591605	182	50.24	2	140	3	108	4.2e-12	40.8	COG2910	Putative NADH-flavin reductase	211
2919591606	59	12.44	5	59	153	203	2.2e-03	11.1	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2919591609	372	76.25	299	366	13	73	1.2e-09	30.3	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2919591614	69	97.01	1	69	1	65	3.1e-35	114.7	COG1278	Cold shock protein, CspA family	67
2919591618	349	74.61	1	308	12	249	9.9e-43	141.2	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2919591620	233	89.78	33	230	10	176	2.1e-44	145.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919591624	230	80	10	121	8	103	6.1e-28	91	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2919591625	263	92.91	4	124	8	125	2.8e-55	87.5	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2919591625	263	92.91	138	261	7	124	2.8e-55	91.5	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2919591626	178	96.18	23	172	5	155	2.6e-23	77.1	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2919591627	210	80.59	6	205	6	142	7.7e-24	78.8	COG0262	Dihydrofolate reductase	167
2919591628	127	86.61	2	126	14	123	8.1e-08	23.8	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2919591629	479	30.65	66	442	658	1015	1.4e-08	26.7	COG1196	Chromosome segregation ATPase	1163
2919591630	179	10.92	10	151	48	140	1.6e-04	14.4	COG3264	Small-conductance mechanosensitive channel	835
2919591632	225	96.94	1	172	4	193	5.9e-31	102.2	COG0693	Putative intracellular protease/amidase	188
2919591636	120	83.94	2	120	17	131	2.3e-18	61.2	COG4319	Ketosteroid isomerase homolog	137
2919591639	546	99.64	1	539	1	548	0.0e+00	613.6	COG0459	Chaperonin GroEL (HSP60 family)	524
2919591640	95	97.92	1	95	1	94	1.5e-42	138.4	COG0234	Co-chaperonin GroES (HSP10)	96
2919591641	66	14.7	3	62	265	310	2.7e-07	23.1	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2919591642	124	31.95	17	124	97	196	5.1e-22	72.5	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2919591643	131	38.99	3	109	130	214	1.1e-09	32.6	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919591655	309	53.87	51	295	121	273	2.3e-09	29.6	COG2801	Transposase InsO and inactivated derivatives	232
2919591657	129	89.22	31	129	9	99	3.0e-32	105.1	COG3162	Uncharacterized membrane protein, DUF485 family	102
2919591659	223	65.75	20	219	18	184	6.6e-26	86.2	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2919591660	604	98.03	1	602	12	609	0.0e+00	448.2	COG2905	Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains	610
2919591661	588	75.78	397	582	24	192	3.2e-30	100.3	COG1226	Voltage-gated potassium channel Kch	212
2919591661	588	95.5	6	400	6	387	7.9e-103	338.5	COG0475	Kef-type K+ transport system, membrane component KefB	397
2919591662	312	98.21	13	291	5	279	4.2e-86	283.5	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2919591664	244	97.55	1	229	5	243	1.4e-62	205.8	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
2919591666	108	69.23	3	89	29	100	1.1e-18	62	COG5467	Uncharacterized protein	104
2919591670	556	97.87	1	553	9	559	2.9e-119	393.5	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2919591673	811	98.49	3	796	12	792	0.0e+00	1316.8	COG3957	Phosphoketolase	793
2919591674	242	95.02	4	228	4	213	1.3e-38	127.4	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2919591675	774	20.31	4	179	10	166	0.0e+00	52.9	COG1554	Trehalose and maltose hydrolase (possible phosphorylase)	772
2919591675	774	67.53	225	762	244	765	0.0e+00	523.2	COG1554	Trehalose and maltose hydrolase (possible phosphorylase)	772
2919591676	531	99.45	5	530	2	542	9.5e-98	321.5	COG2985	Uncharacterized membrane protein YbjL, putative transporter	544
2919591677	797	98.58	9	781	5	766	0.0e+00	665.9	COG1554	Trehalose and maltose hydrolase (possible phosphorylase)	772
2919591678	331	96.64	1	325	6	321	1.5e-90	298	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2919591679	268	75.47	1	144	7	126	7.8e-16	8.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2919591679	268	81.76	144	268	20	149	7.8e-16	45.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2919591681	394	78.79	224	374	23	126	2.3e-18	60.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919591682	115	19.54	14	98	41	91	1.3e-03	12.5	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
2919591684	306	97.71	1	305	1	299	3.1e-92	303.4	COG3781	Predicted membrane chloride channel, bestrophin family	306
2919591685	111	6.81	7	111	55	94	1.6e-03	11.6	COG4715	Uncharacterized conserved protein, contains Zn finger domain	587
2919591686	70	25.16	2	51	19	58	3.0e-03	11.8	COG1580	Flagellar basal body-associated protein FliL	159
2919591691	69	98.51	1	69	1	66	3.8e-35	114.4	COG1278	Cold shock protein, CspA family	67
2919591697	748	93.51	37	745	24	599	1.7e-124	407.3	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
2919591698	581	97.44	77	575	13	507	0.0e+00	553.9	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2919591699	406	98.99	1	405	3	396	9.8e-87	285.7	COG1459	Type II secretory pathway, component PulF	397
2919591700	161	53.21	4	146	5	87	3.1e-09	31.9	COG2165	Type II secretory pathway, pseudopilin PulG	149
2919591703	169	53.52	1	161	101	237	3.7e-20	67.4	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
2919591711	402	87.7	38	377	14	284	8.4e-19	60.9	COG3386	Sugar lactone lactonase YvrE	307
2919591712	627	39.47	358	613	132	221	3.1e-04	14.4	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919591712	627	98.31	1	236	3	234	2.7e-68	224.1	COG3300	MHYT domain, NO-binding membrane sensor	236
2919591714	97	68.18	1	85	13	72	1.7e-04	14.1	COG5552	Uncharacterized protein	88
2919591715	336	90.15	201	332	8	126	2.2e-18	60.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919591719	414	51.11	17	237	69	229	8.2e-11	35.6	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2919591720	364	98.75	1	317	3	319	5.0e-50	165.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919591721	110	89.57	2	110	10	112	1.1e-52	171.4	COG5605	Cytochrome c oxidase subunit IV	115
2919591722	240	94.84	10	240	9	210	3.8e-68	223.3	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2919591723	233	84.51	4	222	30	209	2.1e-32	106.6	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2919591724	589	93.32	24	580	4	534	0.0e+00	678.5	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2919591725	277	92.13	1	277	8	241	1.1e-62	206.1	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2919591726	263	88.24	8	263	26	280	2.3e-73	241.5	COG5473	Uncharacterized membrane protein	290
2919591729	150	86.34	1	149	18	156	5.9e-31	101.9	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
2919591730	278	95.85	1	267	5	258	1.6e-50	165.9	COG2116	Formate/nitrite transporter FocA, FNT family	265
2919591731	578	35.82	275	428	84	155	1.3e-05	18.2	COG2112	Predicted Ser/Thr protein kinase	201
2919591731	578	90.44	2	256	16	261	6.1e-28	89.8	COG0631	Serine/threonine protein phosphatase PrpC	262
2919591732	440	98.85	4	440	4	434	0.0e+00	525.8	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
2919591733	378	91.95	19	378	21	294	1.7e-87	287.6	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2919591734	338	98.43	1	337	4	316	1.6e-74	245.7	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2919591735	649	93.94	21	630	19	561	1.1e-49	164.2	COG0747	ABC-type transport system, periplasmic component	556
2919591737	613	99.09	1	561	4	550	0.0e+00	650.2	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2919591738	658	95.75	1	382	10	392	7.2e-67	219.9	COG4671	Predicted glycosyl transferase	400
2919591739	441	82.89	7	416	57	395	2.2e-35	117.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919591740	423	95.5	2	403	8	389	4.8e-100	329.2	COG4671	Predicted glycosyl transferase	400
2919591741	919	12.33	743	826	443	515	1.8e-40	33	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2919591741	919	73.65	6	504	21	456	1.8e-40	98.1	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2919591742	455	27.91	26	130	16	51	2.4e-01	7.5	COG2149	Uncharacterized membrane protein YidH, DUF202 family	120
2919591742	455	86.89	213	454	20	231	3.7e-41	135.8	COG2114	Adenylate cyclase, class 3	227
2919591743	49	76.19	1	49	15	62	7.2e-14	46.1	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2919591745	316	66.58	56	282	1	263	5.8e-19	63.1	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2919591746	128	85.16	8	125	19	127	7.2e-27	88.8	COG3794	Plastocyanin	128
2919591747	254	88.71	64	252	15	179	6.9e-43	140.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919591748	273	94.16	3	269	10	251	8.6e-37	121.7	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2919591749	568	76.23	349	567	42	227	9.7e-34	111.6	COG2114	Adenylate cyclase, class 3	227
2919591750	296	98.67	4	293	2	298	1.8e-45	150.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919591751	212	87.62	1	204	1	177	3.2e-35	116	COG1182	FMN-dependent NADH-azoreductase	202
2919591752	108	95.28	4	108	4	104	5.3e-29	95.4	COG2076	Multidrug transporter EmrE and related cation transporters	106
2919591753	331	97.97	1	319	3	340	2.8e-69	228.4	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2919591755	248	30.5	144	212	95	137	2.2e-09	22.8	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2919591755	248	48.23	36	130	15	82	2.2e-09	8.6	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2919591756	384	82.5	297	376	11	76	6.4e-11	35.3	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2919591759	283	93.69	1	279	16	297	6.5e-44	145.1	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2919591760	226	93.92	38	186	5	143	1.3e-53	175	COG4957	Predicted transcriptional regulator	148
2919591767	381	93.73	45	376	14	327	1.2e-32	108	COG0582	Integrase	309
2919591769	81	35.77	18	81	26	74	3.9e-03	11.8	COG0295	Cytidine deaminase	134
2919591771	167	10.96	17	153	25	74	5.1e-04	13.7	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2919591775	74	48.92	1	73	1	68	5.3e-12	40.2	COG3415	Transposase	138
2919591778	232	88.97	1	231	25	258	1.2e-59	196.4	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2919591779	515	92.86	4	468	3	418	1.6e-84	278.8	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
2919591780	393	81.17	8	386	74	405	3.9e-34	113.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919591781	632	18.25	159	194	53	75	9.0e-04	4.8	COG3245	Cytochrome c5	126
2919591781	632	42.06	381	476	14	66	9.0e-04	7.3	COG3245	Cytochrome c5	126
2919591783	346	26.32	42	147	18	102	5.2e-28	37.8	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
2919591783	346	49.85	159	343	160	320	5.2e-28	50.2	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
2919591784	276	92.76	56	265	9	213	1.2e-12	42.3	COG2755	Lysophospholipase L1 or related esterase	216
2919591785	328	92.45	1	264	5	249	7.3e-54	177.2	COG0300	Short-chain dehydrogenase	265
2919591787	300	36.58	25	132	1	109	2.8e-59	85.2	COG3246	Uncharacterized conserved protein, DUF849 family	298
2919591787	300	58.39	119	300	123	296	2.8e-59	114	COG3246	Uncharacterized conserved protein, DUF849 family	298
2919591789	400	96.3	3	400	9	398	0.0e+00	480.5	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2919591790	63	81.54	2	62	10	62	9.4e-18	58.9	COG5509	Uncharacterized small protein, DUF1192 family	65
2919591791	599	93.53	450	584	5	134	2.9e-22	73.2	COG0824	Acyl-CoA thioesterase FadM	137
2919591792	829	88.24	74	807	57	641	0.0e+00	439.6	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919591793	463	89.31	22	459	45	420	1.6e-92	305	COG2124	Cytochrome P450	411
2919591794	156	93.92	2	148	4	142	2.2e-53	174.7	COG4957	Predicted transcriptional regulator	148
2919591795	166	93.24	1	147	7	144	1.4e-49	162.3	COG4957	Predicted transcriptional regulator	148
2919591796	459	93.71	22	459	21	452	1.0e-107	355.8	COG3946	Type IV secretory pathway, VirJ component	456
2919591797	881	95.99	18	339	8	318	1.2e-39	131.3	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2919591797	881	99.26	330	881	5	541	0.0e+00	553.2	COG2898	Lysylphosphatidylglycerol synthetase, C-terminal domain, DUF2156 family	538
2919591799	106	91.35	1	97	9	103	3.8e-36	117.6	COG4274	Uncharacterized protein, contains GYD domain	104
2919591800	264	87.89	4	264	27	280	6.6e-75	246.6	COG5473	Uncharacterized membrane protein	290
2919591801	325	98.55	16	299	5	275	7.9e-84	275.5	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
2919591805	142	74.58	2	134	9	140	7.8e-07	22.6	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
2919591806	363	97.33	3	362	7	371	4.4e-109	359.4	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2919591807	219	58.95	70	212	66	177	7.5e-25	81.9	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2919591808	1349	9.9	22	85	32	62	1.5e-51	3.8	COG1216	Glycosyltransferase, GT2 family	305
2919591808	1349	67.09	282	485	3	212	1.5e-51	55	COG1216	Glycosyltransferase, GT2 family	305
2919591808	1349	72.84	1014	1254	3	230	1.5e-51	107.5	COG1216	Glycosyltransferase, GT2 family	305
2919591809	1292	99.32	637	1292	5	591	1.1e-41	137.9	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
2919591815	340	71.76	5	128	18	111	2.5e-15	50.7	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
2919591815	340	80.27	130	336	3	181	9.1e-48	156.4	COG1910	Periplasmic molybdate-binding protein/domain	223
2919591817	266	8.93	231	266	312	342	4.7e-73	25.7	COG2951	Membrane-bound lytic murein transglycosylase B	343
2919591817	266	68.3	3	236	16	252	4.7e-73	217	COG2951	Membrane-bound lytic murein transglycosylase B	343
2919591819	574	95	7	574	17	567	0.0e+00	716.9	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2919591820	434	98.97	7	425	5	390	3.2e-40	132.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919591821	278	98.31	1	277	4	293	2.7e-50	166.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919591822	336	94.61	18	334	8	323	7.4e-39	128	COG1275	Tellurite resistance protein TehA and related permeases	329
2919591823	771	98.79	41	770	3	738	7.9e-126	415.9	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919591824	148	94.87	1	148	4	151	8.9e-56	182.5	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2919591826	264	98.11	1	262	4	263	3.6e-81	266.8	COG0300	Short-chain dehydrogenase	265
2919591827	318	96	1	311	8	319	8.6e-94	308.7	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2919591828	346	98.64	62	340	2	292	1.4e-37	124.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919591829	233	92.67	1	222	13	227	1.1e-53	176.5	COG1802	DNA-binding transcriptional regulator, GntR family	230
2919591830	138	88.97	7	131	7	127	1.2e-03	11.2	COG3631	Ketosteroid isomerase-related protein	133
2919591831	412	84.7	26	398	5	314	4.1e-57	188.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919591832	289	97.67	1	288	5	298	8.8e-66	217	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2919591833	827	95.05	7	316	14	320	2.1e-67	222.4	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2919591833	827	98.31	338	575	4	236	0.0e+00	161.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2919591833	827	98.73	592	826	3	236	0.0e+00	272.5	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2919591834	317	65.3	37	312	78	252	3.7e-12	40.4	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2919591836	468	97.09	5	463	7	473	0.0e+00	433.3	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2919591837	126	77.37	4	123	10	115	3.9e-04	14.6	COG4319	Ketosteroid isomerase homolog	137
2919591838	120	26.8	5	120	141	244	2.4e-02	8	COG3064	Membrane protein involved in colicin uptake	387
2919591839	69	98.51	1	69	1	66	2.9e-34	111.6	COG1278	Cold shock protein, CspA family	67
2919591844	741	97.81	241	739	2	224	3.4e-43	141.4	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919591845	77	60.67	3	74	3	56	2.8e-15	51.5	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
2919591846	461	11.08	15	82	157	195	1.8e-92	12	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2919591846	461	31.82	139	266	223	334	1.8e-92	49.3	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2919591846	461	54.26	248	457	129	319	1.8e-92	241	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2919591847	571	45.87	133	252	130	240	2.6e-38	39.8	COG2202	PAS domain	232
2919591847	571	46.28	257	374	130	241	2.6e-38	38.3	COG2202	PAS domain	232
2919591847	571	49.17	4	130	122	240	2.6e-38	43.8	COG2202	PAS domain	232
2919591849	164	48.35	3	126	122	238	1.1e-09	32.9	COG2202	PAS domain	232
2919591850	475	96.17	281	463	7	182	1.2e-48	159.5	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919591851	411	92.33	18	377	12	336	2.2e-51	168.9	COG1566	Multidrug resistance efflux pump	352
2919591852	154	74.16	22	94	6	71	6.0e-03	11.2	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
2919591854	307	77.78	1	303	72	330	4.0e-81	267.4	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2919591855	550	99.39	23	499	3	487	4.5e-86	284.5	COG3119	Arylsulfatase A or related enzyme	475
2919591856	345	42.92	58	215	23	113	4.6e-09	27.5	COG0560	Phosphoserine phosphatase	212
2919591859	80	71.28	1	69	26	92	8.4e-21	68.7	COG0776	Bacterial nucleoid DNA-binding protein	94
2919591860	210	52.24	3	209	139	313	2.4e-17	58.2	COG0582	Integrase	309
2919591861	344	99.08	4	328	2	324	1.4e-81	269	COG3547	Transposase	303
2919591862	502	57.44	14	296	99	237	2.1e-12	41.8	COG2202	PAS domain	232
2919591862	502	96.04	297	494	7	200	5.1e-43	141	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2919591866	318	80.3	187	318	20	125	5.0e-17	55.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919591867	97	38.07	11	97	41	123	2.0e-08	28.5	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919591868	115	39.45	1	92	128	213	1.7e-12	42	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919591870	279	80.26	16	275	18	200	7.8e-27	88.4	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2919591872	100	68.66	1	92	43	134	4.2e-17	57	COG3335	Transposase	132
2919591873	127	88.49	1	127	4	126	8.3e-22	72.1	COG3415	Transposase	138
2919591875	105	96.81	1	94	2	92	3.1e-28	92.5	COG0776	Bacterial nucleoid DNA-binding protein	94
2919591876	199	83.54	52	194	11	142	2.7e-06	22.3	COG5490	Uncharacterized protein	158
2919591882	252	92.2	6	228	11	211	3.5e-27	89.8	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919591886	319	85.67	21	305	21	277	5.1e-23	73.4	COG4974	Site-specific recombinase XerD	300
2919591887	64	11.8	6	56	161	196	4.3e-03	10.8	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2919591888	141	93.6	1	125	3	119	2.6e-19	64.4	COG3293	Transposase	124
2919591895	123	80.17	11	122	5	97	1.5e-22	74.2	COG5336	FoF1-type ATP synthase assembly protein I	116
2919591897	117	90.1	20	117	7	97	8.7e-30	97.2	COG2154	Pterin-4a-carbinolamine dehydratase	101
2919591900	269	97.28	1	260	7	256	1.4e-45	150.6	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2919591901	181	90.32	4	175	12	179	8.5e-44	143.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919591915	315	92.24	24	310	22	330	4.8e-18	60.2	COG0582	Integrase	309
2919591918	221	51.7	1	186	85	282	8.6e-15	48.6	COG5534	Plasmid replication initiator protein	383
2919591920	87	51.54	7	85	5	71	2.4e-13	45.5	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2919591924	252	92.2	6	219	14	214	2.2e-28	93.4	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919591926	70	43.61	5	69	5	62	7.9e-07	23.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919591927	1304	57.85	962	1098	102	241	3.2e-41	76	COG2202	PAS domain	232
2919591927	1304	58.26	837	972	102	242	3.2e-41	51.1	COG2202	PAS domain	232
2919591927	1304	77.69	540	848	55	242	3.2e-41	36.8	COG2202	PAS domain	232
2919591927	1304	98.52	215	482	2	267	3.5e-76	249.7	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2919591928	159	87.16	3	149	11	139	1.7e-50	165.1	COG4957	Predicted transcriptional regulator	148
2919591929	634	98.44	5	471	2	442	2.5e-84	278.2	COG3276	Selenocysteine-specific translation elongation factor	447
2919591936	59	86.57	1	59	1	58	2.7e-19	63.5	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2919591937	63	12	2	58	373	423	3.3e-07	24.3	COG0840	Methyl-accepting chemotaxis protein	408
2919591938	139	32	2	139	183	318	8.3e-34	111.8	COG0840	Methyl-accepting chemotaxis protein	408
2919591939	420	95.63	207	391	8	182	6.2e-49	160.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919591941	242	96.53	1	242	7	256	2.3e-21	70.4	COG0730	Uncharacterized membrane protein YfcA	258
2919591942	377	95.36	16	375	7	355	4.2e-93	306.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919591944	269	99.16	21	256	2	236	4.2e-100	328	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2919591945	291	98.82	7	268	3	253	1.3e-101	333.4	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2919591946	466	95.05	107	449	11	317	1.1e-101	334.8	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2919591947	305	99.34	1	304	2	300	9.9e-95	311.9	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2919591949	302	73.67	2	282	1	291	4.0e-27	89.9	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2919591950	176	22.51	17	92	15	66	1.3e-03	3.5	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
2919591950	176	45.89	58	176	120	225	1.3e-03	12.6	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
2919591951	246	94.39	4	227	10	211	2.1e-52	171.6	COG2121	Uncharacterized conserved protein, lysophospholipid acyltransferase (LPLAT) superfamily	214
2919591952	434	99.52	9	423	3	418	2.5e-126	415.9	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
2919591953	328	91.07	2	322	9	314	1.1e-85	281.9	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
2919591954	85	90.91	14	85	1	70	6.9e-29	93.9	COG3908	Uncharacterized protein	77
2919591955	136	92.7	1	134	9	135	2.7e-39	128.8	COG0295	Cytidine deaminase	134
2919591956	275	93.54	10	271	17	262	1.3e-72	238.9	COG0005	Purine nucleoside phosphorylase	262
2919591957	254	94.74	13	254	6	221	2.6e-64	211	COG0274	Deoxyribose-phosphate aldolase	228
2919591958	430	96.79	2	429	4	425	0.0e+00	476.6	COG0213	Thymidine phosphorylase	435
2919591959	84	70.53	2	84	12	78	7.8e-05	17.5	COG3767	Uncharacterized low-complexity protein	95
2919591960	200	96.39	6	200	6	192	2.9e-50	165	COG3963	Phospholipid N-methyltransferase	194
2919591961	381	99.22	1	373	1	382	0.0e+00	472.5	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2919591962	637	99.01	1	600	6	605	0.0e+00	894.1	COG0443	Molecular chaperone DnaK (HSP70)	579
2919591964	138	63.49	1	123	44	163	1.9e-15	51.6	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2919591965	200	94.85	2	200	11	194	8.3e-67	218.7	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
2919591966	160	99.4	1	160	1	165	1.2e-58	191.6	COG0678	Peroxiredoxin	165
2919591967	152	92.95	6	151	2	146	7.1e-62	202.3	COG0328	Ribonuclease HI	154
2919591968	321	97.31	1	321	6	331	3.5e-86	283.4	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2919591969	336	96.61	22	317	3	287	3.0e-113	372	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
2919591970	403	96.12	81	384	10	331	2.4e-30	100.3	COG0582	Integrase	309
2919591985	127	48.67	30	120	62	134	5.2e-07	24	COG5652	VanZ like family protein (function unknown)	148
2919591986	493	46.28	5	131	129	240	1.9e-26	44.2	COG2202	PAS domain	232
2919591986	493	46.69	126	253	128	240	1.9e-26	41.1	COG2202	PAS domain	232
2919591988	249	95.41	5	218	7	214	1.1e-28	94.4	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919591991	254	87.61	11	230	21	211	1.2e-24	81.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919592006	80	47.69	3	78	2	63	7.2e-06	21.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2919592018	64	48.06	1	63	67	128	1.0e-18	61.7	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2919592019	98	6.97	14	96	79	119	1.2e-03	11.9	COG4425	Uncharacterized membrane protein	588
2919592021	214	89.57	6	213	12	200	2.2e-34	113.2	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919592026	461	56.94	30	346	175	416	1.1e-49	163.6	COG0840	Methyl-accepting chemotaxis protein	408
2919592030	243	80	174	242	17	80	8.2e-21	66.9	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2919592031	218	93.3	1	207	1	195	1.1e-34	114.2	COG3916	N-acyl-L-homoserine lactone synthetase	209
2919592032	65	7.9	1	56	279	310	2.9e-03	10.7	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2919592035	243	94.04	7	226	12	216	1.7e-24	80.9	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919592038	213	17.89	95	126	12	28	2.5e-03	7.8	COG3432	Predicted transcriptional regulator	95
2919592038	213	33.68	169	212	52	83	2.5e-03	2.4	COG3432	Predicted transcriptional regulator	95
2919592040	411	81.97	172	406	9	208	1.1e-23	78.5	COG2114	Adenylate cyclase, class 3	227
2919592042	206	48.03	4	203	46	179	5.3e-16	53.7	COG0500	SAM-dependent methyltransferase	257
2919592043	391	47.52	212	391	10	191	2.7e-13	11.4	COG0477	MFS family permease	338
2919592043	391	66.06	4	260	8	260	2.7e-13	36.3	COG0477	MFS family permease	338
2919592044	79	15.18	2	72	201	263	7.5e-04	12.7	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
2919592045	214	97.7	1	213	6	217	2.1e-60	198.2	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
2919592046	335	98.31	7	335	4	351	4.7e-99	325.8	COG0306	Phosphate/sulfate permease	326
2919592048	339	91.42	6	241	3	247	3.2e-50	165.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919592049	228	91.59	1	226	12	218	6.9e-20	65.9	COG1842	Phage shock protein A	225
2919592050	90	82.29	1	90	12	90	1.4e-31	103.3	COG4298	Uncharacterized protein	95
2919592053	304	93.17	1	294	1	259	2.5e-65	215	COG3546	Mn-containing catalase (includes spore coat protein CotJC)	277
2919592054	14216	6.61	13089	13131	420	456	6.6e-35	21.7	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919592054	14216	9.64	11842	11934	405	458	6.6e-35	24.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919592054	14216	22.5	13130	13332	324	449	6.6e-35	12.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919592054	14216	25.18	11387	11580	306	446	6.6e-35	12.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919592054	14216	25.36	13192	13434	325	466	6.6e-35	24.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919592054	14216	35.71	10706	10943	248	447	6.6e-35	23.7	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919592054	14216	40.71	12201	12437	227	454	6.6e-35	19.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919592054	14216	43.57	12851	13094	203	446	6.6e-35	39.7	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919592054	14216	44.46	12687	12902	192	440	6.6e-35	21.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919592054	14216	44.82	11170	11404	204	454	6.6e-35	40.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919592054	14216	46.61	10941	11179	187	447	6.6e-35	19.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919592054	14216	47.86	11581	11849	176	443	6.6e-35	40.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919592054	14216	49.29	11927	12217	174	449	6.6e-35	29.7	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919592054	14216	58.75	12335	12849	119	447	6.6e-35	18.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919592056	336	80.3	184	321	21	126	6.3e-16	52	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919592059	79	13.33	1	57	256	307	4.8e-04	13.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919592061	662	21.07	30	232	17	193	0.0e+00	191.2	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
2919592061	662	49.05	233	654	199	610	0.0e+00	411.9	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
2919592063	601	99.17	1	601	4	601	0.0e+00	1020.2	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
2919592064	260	97.57	24	260	3	243	3.7e-52	171.4	COG0748	Putative heme iron utilization protein	245
2919592065	236	98.71	2	236	2	230	3.9e-75	246.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919592066	572	85.53	158	571	56	392	1.2e-59	197.4	COG0642	Signal transduction histidine kinase	336
2919592067	171	44.81	10	159	134	271	3.1e-26	86.6	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
2919592068	133	90.21	1	133	1	129	6.8e-39	127.3	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
2919592069	107	92.13	22	106	7	88	5.6e-27	88	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
2919592071	359	97.55	11	337	1	318	8.1e-82	269.5	COG0523	GTPase, G3E family	323
2919592072	503	83.46	1	500	20	347	1.7e-97	316.7	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2919592073	210	99.08	1	210	2	216	1.3e-38	125.3	COG0602	Organic radical activating enzyme	212
2919592074	118	71.71	1	115	3	111	1.5e-33	107.9	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
2919592075	239	94.59	6	238	4	213	3.0e-70	230.3	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
2919592076	186	88.04	1	186	12	195	1.9e-19	65.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919592077	311	81.54	38	308	27	238	1.6e-27	90.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2919592078	276	95.95	8	155	7	148	4.8e-26	85.6	COG5501	Predicted secreted protein	148
2919592079	199	42.11	17	185	61	108	3.8e-06	18.6	COG0607	Rhodanese-related sulfurtransferase	110
2919592080	132	82.67	7	128	13	136	1.4e-11	39.3	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2919592081	239	93.83	1	213	14	226	7.8e-36	118.1	COG0785	Cytochrome c biogenesis protein CcdA	220
2919592083	274	96.64	9	273	5	263	1.0e-105	347.1	COG0413	Ketopantoate hydroxymethyltransferase	268
2919592084	164	16.85	2	151	29	150	2.2e-14	46.9	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2919592086	100	62.34	1	100	1	96	4.0e-02	7.7	COG3133	Outer membrane lipoprotein SlyB	154
2919592088	152	76.16	5	149	19	149	1.6e-14	48.5	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2919592089	155	96.99	26	153	4	132	1.4e-27	90.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919592092	249	91.73	6	249	13	245	5.0e-82	269.3	COG3346	Cytochrome oxidase assembly protein ShyY1	252
2919592093	142	93.75	3	127	8	112	2.9e-43	140.5	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
2919592094	209	92.02	1	208	17	212	1.6e-73	241	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2919592095	667	99.65	48	617	3	569	0.0e+00	785.2	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2919592096	386	98.82	6	270	3	253	9.6e-82	268.1	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2919592097	444	47.26	255	443	10	190	5.1e-23	9.4	COG0477	MFS family permease	338
2919592097	444	62.14	27	300	8	245	5.1e-23	68.6	COG0477	MFS family permease	338
2919592098	246	75.69	7	216	46	210	2.5e-19	63.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919592099	189	35.17	117	188	81	131	3.0e-16	24.6	COG3212	Uncharacterized membrane protein YkoI	144
2919592099	189	42.76	10	115	81	142	3.0e-16	30	COG3212	Uncharacterized membrane protein YkoI	144
2919592100	334	97.74	4	268	4	262	9.4e-58	189.7	COG0300	Short-chain dehydrogenase	265
2919592101	285	96.04	1	285	1	267	8.0e-73	239.5	COG3546	Mn-containing catalase (includes spore coat protein CotJC)	277
2919592102	169	92.22	2	161	6	159	1.2e-29	97.6	COG3685	Ferritin-like metal-binding protein YciE	167
2919592103	314	75.93	1	298	56	380	4.1e-65	214.7	COG3664	Beta-xylosidase	428
2919592104	258	58.42	6	251	45	207	2.3e-11	38.7	COG0500	SAM-dependent methyltransferase	257
2919592105	197	92.82	1	197	2	195	4.3e-41	135.3	COG0406	Broad specificity phosphatase PhoE	208
2919592106	367	97.35	1	357	4	370	0.0e+00	441.8	COG1260	Myo-inositol-1-phosphate synthase	362
2919592107	350	97.82	1	318	3	316	3.5e-76	251	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919592108	370	95.17	7	361	1	355	8.7e-64	210.1	COG4641	Spore maturation protein CgeB	373
2919592109	368	97.86	3	362	2	366	1.3e-82	272.1	COG4641	Spore maturation protein CgeB	373
2919592110	370	95.44	3	366	4	359	1.3e-56	186.5	COG4641	Spore maturation protein CgeB	373
2919592111	371	76.04	5	359	88	398	6.7e-22	72.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919592113	366	98.75	12	351	3	319	1.0e-74	246.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919592114	370	98.13	4	353	5	319	4.1e-88	290.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919592122	111	78.36	1	108	23	127	1.9e-13	45	COG3335	Transposase	132
2919592124	394	64.3	9	387	109	371	1.1e-22	75.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919592125	191	81.34	56	183	6	114	7.3e-22	71.8	COG3335	Transposase	132
2919592126	762	64.35	22	383	2	232	1.7e-23	78.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2919592126	762	99.02	354	758	4	408	8.3e-38	124.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919592127	385	24.14	23	75	13	47	2.6e-05	7.5	COG1730	Prefoldin subunit 5	145
2919592127	385	29.66	70	126	9	51	2.6e-05	6.1	COG1730	Prefoldin subunit 5	145
2919592128	166	46.93	1	151	170	322	5.7e-23	76.2	COG3547	Transposase	303
2919592130	406	98.74	11	402	5	395	0.0e+00	495.1	COG3328	Transposase (or an inactivated derivative)	379
2919592131	105	83.2	1	105	6	109	3.5e-15	51	COG3293	Transposase	124
2919592132	861	66.5	455	855	136	407	5.8e-19	63.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919592133	64	48.06	1	63	67	128	1.0e-18	61.7	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2919592134	31	11.4	1	31	1	31	2.2e-12	41.2	COG2894	Septum formation inhibitor-activating ATPase MinD	272
2919592135	230	96.51	11	230	6	226	2.0e-49	163	COG0850	Septum formation inhibitor MinC	219
2919592136	218	93.45	1	218	14	227	1.5e-52	173.3	COG0850	Septum formation inhibitor MinC	219
2919592138	534	16.93	366	496	342	416	1.2e-45	.9	COG3182	Uncharacterized iron-regulated membrane protein	442
2919592138	534	87.13	1	371	1	386	1.2e-45	150.8	COG3182	Uncharacterized iron-regulated membrane protein	442
2919592140	608	99.5	1	603	3	602	0.0e+00	969.4	COG1217	Predicted membrane GTPase involved in stress response	603
2919592141	486	40.29	113	197	63	118	1.8e-06	2.6	COG4768	Uncharacterized protein YoxC, contains an MCP-like domain	139
2919592141	486	55.4	366	481	34	110	1.8e-06	12	COG4768	Uncharacterized protein YoxC, contains an MCP-like domain	139
2919592141	486	69.06	238	355	24	119	1.8e-06	11.9	COG4768	Uncharacterized protein YoxC, contains an MCP-like domain	139
2919592145	263	42.6	24	251	76	170	4.9e-05	16.1	COG1226	Voltage-gated potassium channel Kch	212
2919592146	325	98.68	18	320	4	301	9.6e-125	409.9	COG0031	Cysteine synthase	300
2919592148	167	92.41	2	167	6	139	7.5e-18	58.5	COG3187	Heat shock protein HslJ	142
2919592149	107	28.31	20	103	85	131	5.0e-07	23.9	COG1813	Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains	165
2919592150	413	91.4	6	409	1	393	1.9e-67	222.8	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2919592151	320	97.67	4	301	2	295	6.6e-63	207.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919592152	352	95.12	10	335	13	324	2.4e-106	349.6	COG0158	Fructose-1,6-bisphosphatase	326
2919592153	286	99.31	1	285	1	287	0.0e+00	441.8	COG3954	Phosphoribulokinase	289
2919592154	225	96.82	1	219	2	214	2.7e-87	285.8	COG0036	Pentose-5-phosphate-3-epimerase	220
2919592155	253	89.14	2	246	3	199	4.3e-39	128.7	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2919592156	248	99.59	1	240	1	242	4.8e-93	305.5	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
2919592159	187	96.27	8	167	1	155	2.6e-58	190.5	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
2919592160	211	94.3	9	209	5	186	6.5e-55	179.3	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
2919592161	205	99.5	1	204	1	200	3.7e-58	190.7	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
2919592162	229	70.69	5	228	65	228	6.8e-33	108.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919592163	462	99.23	2	462	4	388	9.4e-53	173.9	COG1344	Flagellin and related hook-associated protein FlgL	360
2919592167	241	98.87	1	238	2	263	2.2e-51	166.9	COG4786	Flagellar basal body rod protein FlgG	265
2919592168	446	91.4	7	445	28	431	0.0e+00	486.1	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
2919592169	412	30.93	240	412	327	472	2.4e-87	136.8	COG1749	Flagellar hook protein FlgE	423
2919592169	412	51.69	3	284	4	247	2.4e-87	154.1	COG1749	Flagellar hook protein FlgE	423
2919592170	484	14.46	354	484	503	587	2.0e-73	57.2	COG1256	Flagellar hook-associated protein FlgK	552
2919592170	484	53.57	1	309	1	315	2.0e-73	183.7	COG1256	Flagellar hook-associated protein FlgK	552
2919592171	350	86.86	44	349	47	383	4.8e-18	55.4	COG1344	Flagellin and related hook-associated protein FlgL	360
2919592172	115	99.13	1	115	1	114	8.6e-27	88	COG5442	Flagellar biosynthesis regulator FlaF	115
2919592173	161	87.16	1	137	1	129	1.0e-47	155.9	COG5443	Flagellar biosynthesis regulator FlbT	148
2919592174	131	52.02	2	131	16	131	1.3e-32	107.7	COG1843	Flagellar hook assembly protein FlgD	222
2919592175	88	95.51	1	88	1	85	2.1e-27	89.6	COG1987	Flagellar biosynthesis protein FliQ	89
2919592176	701	97.99	11	701	13	695	0.0e+00	848.9	COG1298	Flagellar biosynthesis pathway, component FlhA	696
2919592177	251	89.15	2	250	10	239	2.0e-51	169.2	COG1684	Flagellar biosynthesis protein FliR	258
2919592183	128	94.81	1	127	7	134	2.4e-26	87	COG1815	Flagellar basal body rod protein FlgB	133
2919592184	138	98.55	3	137	3	138	2.1e-46	151.9	COG1558	Flagellar basal body rod protein FlgC	137
2919592185	115	69.81	4	115	33	106	3.1e-20	66.9	COG1677	Flagellar hook-basal body complex protein FliE	105
2919592186	262	98.49	1	262	2	262	2.6e-94	310	COG4786	Flagellar basal body rod protein FlgG	265
2919592187	154	56.36	8	153	96	219	3.9e-33	109.4	COG1261	Flagella basal body P-ring formation protein FlgA	220
2919592188	373	95.62	6	373	17	365	0.0e+00	460.5	COG1706	Flagellar basal body P-ring protein FlgI	365
2919592189	192	81.54	2	186	30	188	6.8e-39	128.2	COG3334	Flagellar motility protein MotE, a chaperone for MotC folding	192
2919592190	237	96.97	7	234	7	230	5.8e-64	210.1	COG2063	Flagellar basal body L-ring protein FlgH	230
2919592191	162	94.97	1	162	8	158	5.3e-05	15.2	COG1580	Flagellar basal body-associated protein FliL	159
2919592192	258	84.74	6	258	38	248	3.3e-94	309.3	COG1338	Flagellar biosynthetic protein FliP	248
2919592193	567	99.45	3	564	3	547	0.0e+00	436.5	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
2919592195	425	98.52	11	424	3	268	3.4e-73	241	COG1360	Flagellar motor protein MotB	244
2919592198	184	54.46	7	184	111	275	7.0e-19	61.5	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2919592199	227	71.12	3	227	65	229	2.1e-33	110	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919592201	200	93.55	14	198	6	179	4.1e-34	112.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919592202	218	97.18	5	214	4	210	1.0e-11	39.2	COG4944	Uncharacterized protein	213
2919592204	354	95.32	2	353	3	348	4.1e-113	372.3	COG1377	Flagellar biosynthesis protein FlhB	363
2919592205	342	96.76	7	340	11	339	3.0e-75	247.8	COG1536	Flagellar motor switch protein FliG	339
2919592206	107	55.32	3	97	64	141	8.8e-30	98.6	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
2919592208	314	86.79	14	312	39	327	6.0e-57	187.3	COG1868	Flagellar motor switch protein FliM	332
2919592209	289	97	1	283	3	261	2.7e-80	263.4	COG1291	Flagellar motor component MotA	266
2919592210	290	68.72	2	287	42	309	2.2e-30	100.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919592213	101	93.18	1	85	1	82	1.7e-28	92.6	COG0851	Septum formation topological specificity factor MinE	88
2919592214	96	61.79	2	93	6	81	8.4e-08	26.9	COG4737	Uncharacterized protein	123
2919592215	98	54.81	10	93	46	102	3.6e-15	50.4	COG2944	DNA-binding transcriptional regulator YiaG, XRE-type HTH domain	104
2919592216	466	97.62	12	466	9	419	9.0e-90	295.9	COG2124	Cytochrome P450	411
2919592217	118	92.16	15	116	6	99	5.1e-22	72	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
2919592218	333	98.01	11	308	2	296	5.2e-38	125.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919592219	119	22.14	2	104	96	153	1.1e-03	12.5	COG3358	Uncharacterized conserved protein, DUF1684 family	262
2919592220	416	99.01	3	415	4	404	0.0e+00	453.2	COG1972	Nucleoside permease NupC	404
2919592221	275	91.7	5	271	6	248	1.5e-58	192.3	COG0300	Short-chain dehydrogenase	265
2919592222	297	85.53	1	294	43	314	4.8e-66	217.9	COG0657	Acetyl esterase/lipase	312
2919592223	503	97.76	14	463	7	442	4.8e-116	382.9	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2919592225	397	54.86	59	371	13	187	5.3e-18	59.8	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2919592226	177	99.41	5	171	2	169	8.4e-54	176.6	COG5352	Uncharacterized protein	169
2919592227	233	98.71	3	228	2	230	3.0e-90	295.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919592228	239	91.02	1	233	8	230	1.0e-66	219.2	COG0704	Phosphate uptake regulator	240
2919592229	271	98.43	18	271	5	254	9.6e-122	399.5	COG1117	ABC-type phosphate transport system, ATPase component	253
2919592230	300	96.6	18	300	8	291	4.9e-86	282.7	COG0581	ABC-type phosphate transport system, permease component	292
2919592231	325	94.27	13	325	16	311	5.4e-103	338.5	COG0573	ABC-type phosphate transport system, permease component	310
2919592232	346	86.77	4	325	43	324	2.8e-90	297	COG0226	ABC-type phosphate transport system, periplasmic component	318
2919592235	557	99.64	1	557	1	556	0.0e+00	602.3	COG0497	DNA repair ATPase RecN	557
2919592236	292	90.16	13	269	25	253	1.5e-86	284.2	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
2919592237	315	97.34	3	303	3	295	4.0e-104	342.2	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
2919592238	593	93.97	4	367	7	333	0.0e+00	454.9	COG0206	Cell division GTPase FtsZ	338
2919592239	440	86.18	16	417	6	379	7.7e-124	408	COG0849	Cell division ATPase FtsA	418
2919592240	311	78.6	89	303	58	270	4.0e-39	128.5	COG1589	Cell division septal protein FtsQ	269
2919592241	307	99.37	1	304	2	317	1.5e-98	324.2	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
2919592242	306	97.28	19	306	5	290	1.9e-94	310.2	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
2919592243	468	98.48	1	465	6	459	0.0e+00	585.6	COG0773	UDP-N-acetylmuramate-alanine ligase	459
2919592244	369	99.16	6	368	2	356	4.7e-93	306.6	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
2919592245	388	97.91	4	374	5	378	4.0e-99	326.2	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
2919592246	455	99.11	3	455	3	448	0.0e+00	453.9	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
2919592247	361	98.77	19	361	2	323	1.1e-108	357.6	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2919592248	491	99.56	9	475	2	453	0.0e+00	432.9	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
2919592249	491	96.9	6	489	15	483	0.0e+00	464.4	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
2919592250	646	93.2	80	618	22	610	9.4e-101	331.8	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2919592251	151	66.67	1	116	2	93	9.0e-18	58.9	COG5462	Predicted secreted (periplasmic) protein	138
2919592252	353	98.41	15	327	4	313	1.7e-110	363.9	COG0275	16S rRNA C1402 N4-methylase RsmH	314
2919592255	146	99.32	1	126	1	145	7.9e-25	83.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919592256	286	93.42	22	249	17	243	1.4e-59	195.4	COG3959	Transketolase, N-terminal subunit	243
2919592257	301	93.59	1	300	13	304	1.1e-50	166.3	COG3958	Transketolase, C-terminal subunit	312
2919592258	655	92.76	336	642	7	339	6.6e-25	82.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2919592258	655	97.82	13	321	4	317	8.5e-46	150.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919592260	264	58.42	5	236	32	194	3.7e-10	34.7	COG0500	SAM-dependent methyltransferase	257
2919592261	884	99.54	1	872	4	866	0.0e+00	788.1	COG0308	Aminopeptidase N	859
2919592262	792	80.71	320	758	72	389	1.7e-70	233.1	COG0642	Signal transduction histidine kinase	336
2919592263	974	8.83	890	974	369	453	0.0e+00	14.9	COG1391	Glutamine synthetase adenylyltransferase	963
2919592263	974	91.07	20	934	45	921	0.0e+00	871	COG1391	Glutamine synthetase adenylyltransferase	963
2919592264	475	85.28	114	475	57	392	9.8e-61	200.9	COG0642	Signal transduction histidine kinase	336
2919592265	232	99.14	1	228	1	230	2.3e-80	263.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919592267	200	91.71	3	200	14	179	8.4e-23	75.1	COG5342	Invasion protein IalB, involved in pathogenesis	181
2919592268	280	37.23	70	274	61	162	8.8e-02	10.9	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2919592269	457	73.1	88	435	76	306	2.9e-54	179	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2919592270	97	99	1	97	1	99	2.8e-26	86.1	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
2919592273	884	98.51	12	878	9	801	0.0e+00	902.9	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2919592274	351	93.13	2	324	16	327	5.0e-76	250.3	COG3520	Predicted component of the type VI protein secretion system	335
2919592275	657	99.68	1	657	1	619	0.0e+00	474.8	COG3519	Type VI protein secretion system component VasA	621
2919592276	181	80.89	42	181	29	155	2.1e-24	80.1	COG3518	Predicted component of the type VI protein secretion system	157
2919592277	160	96.84	1	159	1	153	1.4e-45	149.3	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2919592278	503	97.17	6	503	13	493	0.0e+00	682.1	COG3517	Predicted component of the type VI protein secretion system	495
2919592279	186	95.86	2	172	3	164	1.6e-56	184.8	COG3516	Predicted component of the type VI protein secretion system	169
2919592280	439	13.31	369	431	290	336	2.0e-13	19.6	COG3515	Predicted component of the type VI protein secretion system	346
2919592280	439	69.12	73	339	95	338	2.0e-13	19.7	COG3515	Predicted component of the type VI protein secretion system	346
2919592281	182	57.29	20	182	84	197	1.1e-31	105	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2919592282	582	91.35	1	538	31	558	0.0e+00	502.8	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2919592284	473	97.69	1	472	3	424	1.0e-82	272.7	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
2919592285	384	85.87	1	381	63	445	2.9e-99	327.1	COG3522	Predicted component of the type VI protein secretion system	446
2919592286	484	84.47	49	319	38	260	2.9e-57	188.2	COG3455	Type VI protein secretion system component VasF	262
2919592287	1204	98.99	1	1204	10	1188	0.0e+00	989	COG3523	Type VI protein secretion system component VasK	1188
2919592288	230	62.11	1	159	7	147	2.8e-28	91.3	COG3913	Uncharacterized protein	227
2919592289	273	94.12	18	261	5	260	1.2e-61	202.7	COG0631	Serine/threonine protein phosphatase PrpC	262
2919592295	137	99.32	5	130	2	146	6.8e-16	54.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919592296	517	92.92	1	517	10	508	0.0e+00	548.4	COG0578	Glycerol-3-phosphate dehydrogenase	532
2919592297	502	98.8	1	499	5	499	0.0e+00	692	COG0554	Glycerol kinase	499
2919592298	210	98.56	2	209	3	207	1.8e-54	178.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2919592299	303	96.35	7	301	7	296	6.5e-39	128.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919592300	364	94.64	200	362	9	167	4.9e-49	160.7	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2919592300	364	94.71	14	200	6	184	1.5e-65	214.1	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
2919592301	321	96.54	28	312	1	279	9.9e-65	213.1	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
2919592303	158	36.32	25	140	70	150	1.4e-01	4.6	COG3235	Uncharacterized membrane protein	223
2919592304	218	98.58	5	218	2	209	6.6e-44	144.4	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919592305	42	6.55	1	42	9	46	2.5e-08	26.2	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2919592306	39	6.34	1	39	1	39	1.3e-16	54.6	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
2919592307	468	99.35	18	457	2	457	0.0e+00	532	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
2919592308	533	91.59	32	533	40	529	0.0e+00	446.5	COG3131	Periplasmic glucans biosynthesis protein	534
2919592309	721	94.29	13	719	26	719	0.0e+00	815.1	COG2943	Membrane glycosyltransferase	736
2919592311	326	98.49	4	326	5	330	4.7e-78	257.4	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2919592312	136	67.8	3	130	12	91	4.2e-09	31.2	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2919592317	745	97.86	1	745	18	795	6.6e-105	347.1	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2919592321	120	97.25	13	120	2	107	1.1e-43	142.4	COG1742	Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily	109
2919592322	181	81.96	3	176	29	187	5.1e-32	105.1	COG1525	Endonuclease YncB, thermonuclease family	192
2919592324	425	83.54	1	391	2	341	1.1e-41	137.7	COG0644	Dehydrogenase (flavoprotein)	396
2919592325	736	63.5	244	723	219	639	7.6e-107	352.2	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919592326	253	97.25	19	225	5	216	2.8e-15	50.9	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919592327	283	96.33	33	250	6	215	1.3e-21	71.4	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919592328	695	97.36	1	695	22	795	7.0e-37	114.1	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2919592330	126	29.9	5	126	130	245	5.1e-03	10.3	COG3064	Membrane protein involved in colicin uptake	387
2919592331	662	97.68	38	662	15	603	7.6e-93	306.6	COG0729	Outer membrane translocation and assembly module TamA	594
2919592332	1446	2.25	361	402	936	965	0.0e+00	6.9	COG2911	Autotransporter translocation and assembly factor TamB	1278
2919592332	1446	25.19	10	369	17	352	0.0e+00	132	COG2911	Autotransporter translocation and assembly factor TamB	1278
2919592332	1446	60.64	534	1446	520	1328	0.0e+00	463.5	COG2911	Autotransporter translocation and assembly factor TamB	1278
2919592333	137	34.97	30	125	102	158	2.4e-06	13.2	COG5126	Ca2+-binding protein, EF-hand superfamily	160
2919592335	164	97.63	1	163	2	166	9.5e-41	133.6	COG0242	Peptide deformylase	168
2919592341	222	97.3	1	217	2	217	2.8e-46	152.8	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2919592343	161	34.35	15	160	47	181	7.8e-01	3.6	COG2948	Type IV secretory pathway, VirB10 components	360
2919592349	439	20.04	2	113	13	114	4.6e-54	41.1	COG3202	ATP/ADP translocase	509
2919592349	439	66.8	115	428	148	487	4.6e-54	131.7	COG3202	ATP/ADP translocase	509
2919592350	240	97.16	33	239	3	207	2.4e-47	155.3	COG2085	Predicted dinucleotide-binding enzyme	211
2919592351	304	95.31	33	303	4	308	8.9e-46	145.5	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2919592355	1031	75.81	435	1031	7	592	0.0e+00	792.3	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
2919592355	1031	97.77	21	434	8	401	6.1e-102	335.9	COG0506	Proline dehydrogenase	391
2919592358	147	94.04	1	147	4	145	2.4e-31	103.3	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
2919592359	353	97.53	10	321	8	323	2.4e-64	212.1	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2919592360	349	96.42	12	348	10	332	1.5e-94	311.2	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2919592361	261	94.19	5	259	2	244	3.0e-79	260.4	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
2919592365	814	57.64	401	762	198	476	5.8e-24	76.2	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2919592366	53	20.51	15	53	5	36	1.1e-10	36.9	COG2165	Type II secretory pathway, pseudopilin PulG	149
2919592367	30	9.86	1	30	263	291	2.3e-04	13.8	COG0074	Succinyl-CoA synthetase, alpha subunit	293
2919592368	150	26.63	1	129	22	123	3.6e-07	24.8	COG0477	MFS family permease	338
2919592369	230	87.5	3	224	11	213	1.4e-45	149.9	COG1802	DNA-binding transcriptional regulator, GntR family	230
2919592371	572	91.57	22	180	11	162	1.1e-23	77.5	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2919592371	572	94.34	167	567	17	416	1.6e-117	384.5	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2919592372	989	21.27	68	285	8	215	0.0e+00	161.2	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2919592372	989	69.02	281	985	262	936	0.0e+00	733.8	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2919592374	360	56.25	80	355	119	316	1.7e-56	186.7	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2919592377	656	98.11	1	521	3	520	0.0e+00	667.9	COG4670	Acyl CoA:acetate/3-ketoacid CoA transferase	527
2919592378	671	96.16	2	669	11	711	5.6e-128	422.5	COG0480	Translation elongation factor EF-G, a GTPase	697
2919592379	531	92.23	52	435	27	394	2.3e-73	242.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919592380	127	90.38	1	104	4	97	8.1e-19	62.5	COG5467	Uncharacterized protein	104
2919592382	464	90.1	41	459	1	437	9.3e-80	263.1	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2919592383	289	72.26	5	258	86	309	8.3e-12	35	COG3021	Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily	309
2919592384	419	84.41	4	376	3	343	1.1e-35	116.4	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
2919592385	1154	98.78	1	1154	1	972	5.7e-78	247.6	COG4717	Uncharacterized protein YhaN	984
2919592388	145	89.19	1	144	8	139	1.4e-62	204.6	COG4957	Predicted transcriptional regulator	148
2919592389	717	98.98	9	717	3	678	0.0e+00	873.5	COG1770	Protease II	682
2919592392	789	98.96	39	676	2	665	0.0e+00	778.8	COG0210	Superfamily I DNA or RNA helicase	655
2919592393	228	62.06	2	228	118	328	1.6e-67	222.7	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
2919592395	506	70.33	5	268	29	239	1.7e-77	254.9	COG3034	Murein L,D-transpeptidase YafK	298
2919592396	317	98.42	1	317	3	314	0.0e+00	441.7	COG0825	Acetyl-CoA carboxylase alpha subunit	317
2919592397	261	99.63	1	260	1	267	2.6e-74	244.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919592398	114	94.03	1	66	2	64	1.6e-14	48.2	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2919592399	205	96.14	3	203	2	200	3.7e-18	60.5	COG2039	Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)	207
2919592400	329	97.83	5	328	3	318	3.2e-120	395.6	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
2919592401	347	77.25	42	345	29	320	5.8e-60	196.6	COG4782	Esterase/lipase superfamily enzyme	377
2919592403	307	95.29	1	303	4	327	3.6e-27	89.1	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
2919592404	324	43.1	15	134	7	131	1.4e-47	84.3	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
2919592404	324	43.1	170	324	160	284	1.4e-47	72.6	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
2919592407	306	67.35	6	225	53	250	1.6e-28	93.2	COG0777	Acetyl-CoA carboxylase beta subunit	294
2919592410	88	34.48	1	88	14	93	5.3e-29	96	COG1802	DNA-binding transcriptional regulator, GntR family	230
2919592416	142	41.51	2	80	7	50	7.5e-04	14.1	COG3097	Uncharacterized protein YqfB, UPF0267 family	106
2919592420	522	81.41	25	517	78	423	1.5e-62	206.2	COG0840	Methyl-accepting chemotaxis protein	408
2919592423	229	85.58	10	227	13	196	2.0e-10	33.5	COG0625	Glutathione S-transferase	211
2919592424	63	37.97	1	60	97	156	6.0e-13	44	COG1555	DNA uptake protein ComE and related DNA-binding proteins	149
2919592425	292	98.67	1	291	1	297	2.4e-64	212.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919592426	599	70.97	424	591	17	148	5.2e-07	24.7	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2919592426	599	93.67	9	399	20	389	1.1e-05	18.1	COG2814	Predicted arabinose efflux permease, MFS family	394
2919592428	317	98.04	4	309	6	305	4.5e-67	221.3	COG4286	Uncharacterized protein, UPF0160 family	306
2919592430	805	65.99	337	672	133	392	1.2e-46	154.9	COG0642	Signal transduction histidine kinase	336
2919592431	716	65.93	583	715	6	125	1.3e-07	24.9	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2919592431	716	81.22	150	574	71	390	1.6e-52	174.2	COG0642	Signal transduction histidine kinase	336
2919592432	1050	47.11	542	658	126	239	6.1e-60	29.1	COG2202	PAS domain	232
2919592432	1050	56.61	280	415	106	242	6.1e-60	62	COG2202	PAS domain	232
2919592432	1050	58.26	404	540	102	242	6.1e-60	55.3	COG2202	PAS domain	232
2919592432	1050	67.22	651	915	113	356	4.7e-32	95.5	COG3852	Signal transduction histidine kinase, nitrogen specific	363
2919592432	1050	73.97	51	286	64	242	6.1e-60	75	COG2202	PAS domain	232
2919592433	62	48.31	4	58	3	45	3.2e-13	44.8	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
2919592436	575	74.87	67	420	95	389	1.7e-54	180	COG0642	Signal transduction histidine kinase	336
2919592437	153	89.47	4	141	7	125	9.0e-26	84.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919592438	751	98.27	3	751	8	744	0.0e+00	792.3	COG4251	Bacteriophytochrome (light-regulated signal transduction histidine kinase)	750
2919592439	684	72.08	57	543	106	389	1.0e-47	154	COG0642	Signal transduction histidine kinase	336
2919592440	508	87.74	254	482	6	234	1.1e-65	67.7	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
2919592440	508	92.34	15	256	4	244	1.1e-65	146.3	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
2919592441	63	48.31	3	60	3	45	2.4e-13	45.3	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
2919592442	684	61.54	553	680	8	119	4.3e-05	17.2	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2919592442	684	63.71	217	544	140	390	1.8e-48	160.1	COG0642	Signal transduction histidine kinase	336
2919592446	379	97.12	7	372	8	378	0.0e+00	464.9	COG3448	CBS-domain-containing membrane protein	382
2919592448	95	14.92	6	94	312	368	2.4e-05	17.9	COG3448	CBS-domain-containing membrane protein	382
2919592451	413	88.43	153	413	1	237	5.7e-67	219.6	COG1018	Ferredoxin-NADP reductase	266
2919592451	413	98.67	4	153	2	149	9.8e-54	176	COG1017	Hemoglobin-like flavoprotein	150
2919592452	160	90.67	1	144	1	136	1.2e-42	140	COG1959	DNA-binding transcriptional regulator, IscR family	150
2919592453	332	80.3	201	332	20	125	3.3e-21	69.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919592455	60	8.29	2	60	565	615	6.8e-19	62.3	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
2919592456	407	99.25	26	407	2	397	4.4e-104	343.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919592457	610	99.04	2	608	3	622	0.0e+00	677.7	COG0326	Molecular chaperone, HSP90 family	623
2919592459	537	52.63	406	509	43	112	1.4e-02	8.7	COG2346	Truncated hemoglobin YjbI	133
2919592462	142	99.19	5	123	1	123	1.4e-33	109.8	COG4933	Predicted transcriptional regulator, contains an HTH and PUA-like domains	124
2919592463	183	87.89	1	182	6	172	3.8e-25	82.8	COG2019	Archaeal adenylate kinase	189
2919592465	188	67.7	1	163	3	155	3.7e-39	129.2	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2919592466	445	57.54	4	319	79	345	1.4e-19	64.7	COG4325	Uncharacterized membrane protein	464
2919592467	334	92.5	4	333	19	351	1.9e-54	178	COG0628	Predicted PurR-regulated permease PerM	355
2919592468	238	81.19	1	175	40	216	2.1e-18	61.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919592469	686	70.67	267	679	111	375	6.7e-61	201.3	COG4585	Signal transduction histidine kinase	365
2919592470	218	99.53	4	213	1	210	6.4e-65	213.3	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919592471	153	42.24	1	143	159	286	5.1e-14	46.8	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2919592472	94	25.08	9	94	12	87	3.7e-12	40.7	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2919592473	435	29.55	204	263	5	30	2.3e-08	9.7	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2919592473	435	73.86	329	393	5	69	2.3e-08	17.1	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2919592480	104	48.23	2	88	10	77	4.7e-02	9.1	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
2919592481	379	97.64	6	373	6	378	0.0e+00	472.4	COG3448	CBS-domain-containing membrane protein	382
2919592482	722	9.62	182	259	191	251	0.0e+00	14.9	COG1042	Acyl-CoA synthetase (NDP forming)	598
2919592482	722	24.76	3	178	475	631	0.0e+00	118.1	COG1042	Acyl-CoA synthetase (NDP forming)	598
2919592482	722	69.72	265	718	3	444	0.0e+00	429.8	COG1042	Acyl-CoA synthetase (NDP forming)	598
2919592483	273	59.85	1	264	159	398	1.5e-56	186.6	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2919592485	78	72.84	2	75	11	69	9.6e-24	77.6	COG1722	Exonuclease VII small subunit	81
2919592486	170	93.02	1	160	13	172	1.1e-58	192.1	COG5350	Predicted protein tyrosine phosphatase	172
2919592487	196	94.85	16	196	1	184	4.2e-26	86.7	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
2919592488	231	96.81	34	220	3	184	1.2e-74	244.5	COG2818	3-methyladenine DNA glycosylase Tag	188
2919592489	285	93.51	1	282	17	304	4.3e-63	208	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
2919592490	445	98.38	5	430	2	425	0.0e+00	463.9	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2919592492	165	86.72	39	165	17	127	5.2e-34	111.7	COG5451	Predicted secreted protein	128
2919592493	153	93.15	8	149	8	143	3.4e-27	89.7	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2919592495	240	96.64	1	239	9	267	1.7e-60	199.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919592496	212	92.06	6	212	18	214	3.1e-83	273	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
2919592497	169	69.12	19	161	40	133	6.0e-12	40.3	COG4520	Surface antigen	136
2919592498	319	33.25	175	318	221	348	8.7e-67	92.5	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2919592498	319	37.66	1	183	6	150	8.7e-67	122.7	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2919592499	286	98.46	18	278	2	256	4.0e-116	381.3	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
2919592500	332	84.44	69	317	41	268	7.3e-81	266	COG2326	Polyphosphate kinase 2, PPK2 family	270
2919592501	195	91.39	1	195	2	192	7.0e-50	164.2	COG0406	Broad specificity phosphatase PhoE	208
2919592502	1361	33.16	750	851	90	152	4.0e-14	17.5	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2919592502	1361	33.16	971	1086	91	153	4.0e-14	10.7	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2919592502	1361	47.89	1257	1361	88	178	4.0e-14	22.7	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2919592502	1361	95.6	37	541	13	555	1.9e-72	238.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919592504	218	97.62	1	212	4	208	2.3e-86	282.8	COG2945	Alpha/beta superfamily hydrolase	210
2919592505	389	98.19	4	388	2	380	1.3e-122	404	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
2919592506	489	99.77	40	487	1	433	0.0e+00	527.4	COG0719	Fe-S cluster assembly scaffold protein SufB	412
2919592507	250	97.22	1	250	3	247	1.7e-106	349.7	COG0396	Fe-S cluster assembly ATPase SufC	251
2919592508	440	76.5	10	431	91	422	4.9e-56	185	COG0719	Fe-S cluster assembly scaffold protein SufB	412
2919592509	414	99.02	8	414	3	407	0.0e+00	527.8	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
2919592510	126	92.92	17	126	5	109	2.5e-38	125	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
2919592511	125	96.36	5	113	4	109	6.0e-37	120.5	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2919592512	354	95.63	150	342	6	180	2.1e-47	155.3	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919592513	508	88.27	1	489	36	494	0.0e+00	483.2	COG0513	Superfamily II DNA and RNA helicase	513
2919592515	51	17.8	2	51	1	42	1.0e-05	18.9	COG3637	Opacity protein and related surface antigens	199
2919592516	480	90.16	255	468	17	181	1.1e-51	168.8	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919592517	348	92.7	1	345	17	359	1.5e-93	308.2	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2919592518	475	45.92	9	179	9	98	7.6e-09	29.3	COG4961	Flp pilus assembly protein TadG	185
2919592520	273	93.66	2	273	10	275	1.8e-39	130.4	COG2801	Transposase InsO and inactivated derivatives	232
2919592521	126	87.18	8	116	5	106	2.3e-20	67.5	COG2963	Transposase and inactivated derivatives	116
2919592523	54	23.61	1	53	18	68	2.0e-15	51.5	COG3316	Transposase (or an inactivated derivative)	215
2919592524	61	29.38	1	61	44	95	2.7e-04	15.9	COG2322	Uncharacterized membrane protein YozB, DUF420 family	177
2919592526	308	50.54	57	301	55	195	7.3e-04	14.6	COG0500	SAM-dependent methyltransferase	257
2919592527	666	81.9	86	662	102	644	1.2e-92	305.5	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919592529	100	65.41	1	95	5	91	1.0e-06	23.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919592530	362	48.3	78	352	147	316	1.6e-61	203.2	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2919592531	361	72.62	283	360	12	72	1.0e-06	23.2	COG2770	HAMP domain	83
2919592532	656	84.55	69	526	35	461	8.3e-70	230.2	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2919592533	401	28.69	207	341	179	279	5.3e-18	22.8	COG1566	Multidrug resistance efflux pump	352
2919592533	401	46.02	1	202	22	183	5.3e-18	29.6	COG1566	Multidrug resistance efflux pump	352
2919592534	772	63.74	634	765	10	125	1.7e-06	21.2	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2919592534	772	95.87	251	627	12	359	9.7e-27	88	COG3852	Signal transduction histidine kinase, nitrogen specific	363
2919592534	772	97.88	1	236	5	235	9.6e-63	205.9	COG3300	MHYT domain, NO-binding membrane sensor	236
2919592536	557	81.18	109	552	79	423	3.1e-62	205.9	COG0840	Methyl-accepting chemotaxis protein	408
2919592537	351	82.24	1	303	4	267	2.1e-20	67.9	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919592538	225	84.81	17	217	23	223	1.7e-29	97	COG0412	Dienelactone hydrolase	236
2919592542	256	97.61	1	255	5	249	1.2e-76	251.9	COG1496	Copper oxidase (laccase) domain	249
2919592544	356	94.59	3	350	8	357	2.2e-94	310.8	COG1565	SAM-dependent methyltransferase, MidA family	370
2919592545	296	96.88	2	289	5	283	7.6e-83	272.2	COG0682	Prolipoprotein diacylglyceryltransferase	287
2919592546	392	96.61	2	392	14	412	1.0e-81	262.2	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2919592547	330	59.88	21	330	55	354	2.6e-35	116.7	COG0753	Catalase	496
2919592548	301	76.71	164	301	2	113	5.6e-13	28.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919592548	301	93.84	7	146	9	145	5.6e-13	19.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919592549	299	98.38	5	299	2	305	5.1e-79	260.1	COG3386	Sugar lactone lactonase YvrE	307
2919592551	160	83.33	2	140	14	133	4.7e-20	66.8	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2919592552	522	97.36	1	521	5	557	1.8e-68	221.8	COG2303	Choline dehydrogenase or related flavoprotein	542
2919592554	511	98.59	2	495	5	494	1.0e-71	236.9	COG1233	Phytoene dehydrogenase-related protein	487
2919592555	291	74.09	2	287	19	261	1.4e-51	169.9	COG0142	Geranylgeranyl pyrophosphate synthase	322
2919592556	391	58.42	161	382	41	203	1.9e-07	25	COG0500	SAM-dependent methyltransferase	257
2919592557	312	98.87	3	308	5	353	3.3e-29	89.5	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2919592558	327	96.04	29	298	2	268	2.4e-69	228.1	COG1348	Nitrogenase subunit NifH, an ATPase	278
2919592559	536	88.86	86	498	31	437	3.5e-04	11.6	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2919592560	488	19.65	6	104	38	127	4.4e-17	9.4	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2919592560	488	54.37	150	403	191	439	4.4e-17	39.7	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2919592567	39	5.69	2	39	12	44	1.8e-06	20	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2919592569	69	92.96	1	68	4	69	2.4e-15	51.5	COG3360	Flavin-binding protein dodecin	71
2919592571	1065	38.43	66	159	144	236	8.2e-64	9.5	COG2202	PAS domain	232
2919592571	1065	50	538	679	121	241	8.2e-64	40.1	COG2202	PAS domain	232
2919592571	1065	58.68	266	417	101	242	8.2e-64	58.9	COG2202	PAS domain	232
2919592571	1065	59.92	394	543	98	242	8.2e-64	81.9	COG2202	PAS domain	232
2919592571	1065	62.4	118	274	70	220	8.2e-64	46.3	COG2202	PAS domain	232
2919592571	1065	93.23	759	1065	4	127	1.0e-22	73.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919592573	1065	17.32	724	824	336	432	2.2e-30	17.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919592573	1065	20.71	758	903	343	458	2.2e-30	44.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919592573	1065	32.5	828	1034	307	488	2.2e-30	69.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919592575	451	86.87	119	436	16	306	2.7e-16	54.4	COG0582	Integrase	309
2919592576	117	43.97	1	111	3	104	7.4e-10	33.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919592577	264	93.12	12	238	10	212	3.7e-26	86.4	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919592579	501	90.42	8	251	7	242	1.3e-69	142.9	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
2919592579	501	93.49	249	485	3	246	1.3e-69	84	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
2919592582	366	88.64	229	364	11	127	5.2e-16	52.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919592584	223	88.5	4	217	2	201	1.0e-30	100.8	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2919592586	88	94.32	1	86	1	83	3.5e-27	88.8	COG0851	Septum formation topological specificity factor MinE	88
2919592588	419	86.26	123	412	37	306	1.3e-55	182.7	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2919592589	139	82.02	14	95	2	74	5.1e-11	37.6	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
2919592590	89	72.73	1	41	3	34	3.6e-04	14.4	COG5510	Predicted small secreted protein	44
2919592591	78	18.85	1	68	196	244	7.0e-07	24	COG1484	DNA replication protein DnaC	254
2919592593	372	80.3	26	370	60	377	4.8e-53	175.1	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2919592594	229	34.26	1	207	5	127	5.9e-15	50.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2919592595	318	83.8	1	316	26	325	8.4e-31	101.7	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2919592597	257	91	1	209	10	201	2.9e-26	86.6	COG3222	Uncharacterized conserved protein, glycosyltransferase A (GT-A) superfamily, DUF2064 family	211
2919592598	241	87.2	9	241	4	255	1.5e-54	179.6	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2919592599	221	87.33	1	210	21	213	6.8e-58	190.4	COG4117	Thiosulfate reductase cytochrome b subunit	221
2919592603	313	97.34	12	304	1	293	2.6e-56	186	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919592604	86	7.61	10	77	296	336	4.8e-04	13.2	COG1292	Choline-glycine betaine transporter	537
2919592606	352	56.31	73	242	4	128	1.4e-06	22.5	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2919592609	52	9.89	1	47	427	473	2.3e-16	54.3	COG5361	Uncharacterized conserved protein	458
2919592613	171	95.27	1	147	5	145	5.5e-55	179.8	COG4957	Predicted transcriptional regulator	148
2919592614	181	68.42	53	177	6	96	1.0e-12	42.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919592625	139	83.78	1	129	21	144	3.3e-43	141.6	COG4957	Predicted transcriptional regulator	148
2919592628	428	88.66	38	409	22	318	1.5e-28	94.3	COG0582	Integrase	309
2919592629	298	96.68	4	298	2	292	2.0e-78	258.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919592630	422	98.23	29	419	5	392	6.1e-112	368.5	COG2814	Predicted arabinose efflux permease, MFS family	394
2919592634	356	11.39	56	302	31	57	4.0e-03	10.6	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
2919592636	199	77.22	51	194	21	142	2.5e-07	25.6	COG5490	Uncharacterized protein	158
2919592638	324	96.95	43	317	3	288	5.6e-42	138.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919592639	81	32.88	3	80	149	221	3.4e-14	47.9	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2919592640	369	93.95	27	367	9	334	9.5e-60	196.8	COG3239	Fatty acid desaturase	343
2919592641	286	75.74	2	266	14	269	5.1e-24	79.5	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2919592651	287	72.22	33	231	42	184	1.1e-22	75.2	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2919592652	331	97.07	11	316	4	301	1.6e-56	186.1	COG0492	Thioredoxin reductase	305
2919592659	469	95.18	10	456	3	417	5.7e-93	306.2	COG0305	Replicative DNA helicase	435
2919592660	311	83.01	4	141	4	130	2.6e-28	93	COG3756	Uncharacterized conserved protein YdaU, DUF1376 family	153
2919592667	225	72.01	1	216	4	196	8.4e-24	79.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919592668	295	92.07	34	287	17	225	4.7e-11	36.5	COG5012	Methanogenic corrinoid protein MtbC1	227
2919592672	407	93.44	144	324	10	180	2.4e-50	165.1	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919592674	263	64.78	2	255	108	324	8.3e-07	21.1	COG0582	Integrase	309
2919592678	1035	99.61	2	1009	2	1011	0.0e+00	980.5	COG0841	Multidrug efflux pump subunit AcrB	1009
2919592679	401	96.41	1	391	8	383	5.0e-60	198.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919592680	492	98.72	85	477	6	390	0.0e+00	438.1	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
2919592681	161	94.55	7	116	4	107	2.2e-12	41.7	COG1544	Ribosome-associated translation inhibitor RaiA	110
2919592685	174	94.52	16	165	9	146	1.5e-36	119.9	COG0071	Molecular chaperone IbpA, HSP20 family	146
2919592686	160	93.15	1	138	10	145	1.0e-36	120.5	COG0071	Molecular chaperone IbpA, HSP20 family	146
2919592688	132	31.62	1	126	243	359	6.5e-36	118.6	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2919592689	52	16.33	1	45	33	64	7.3e-04	14.1	COG4961	Flp pilus assembly protein TadG	185
2919592690	552	86.12	124	547	58	423	1.1e-58	194.2	COG0840	Methyl-accepting chemotaxis protein	408
2919592691	325	85.75	6	323	46	358	1.5e-80	261.6	COG1858	Cytochrome c peroxidase	364
2919592692	67	20	3	66	24	57	1.9e-03	12.8	COG0262	Dihydrofolate reductase	167
2919592693	45	17.67	1	45	1	41	3.5e-07	24.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919592694	452	97.29	8	450	11	440	0.0e+00	553.1	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
2919592695	135	83.78	1	135	15	138	1.2e-05	18.6	COG2882	Flagellar biosynthesis chaperone FliJ	148
2919592696	351	96.6	1	317	7	319	1.2e-60	200	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2919592699	712	97.85	21	712	13	694	0.0e+00	880.5	COG1298	Flagellar biosynthesis pathway, component FlhA	696
2919592702	414	91.67	44	413	19	359	3.8e-64	211.4	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
2919592703	217	85.66	2	217	28	242	2.9e-70	231.2	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
2919592704	849	70.62	316	474	2	126	9.8e-15	48.1	COG4935	Regulatory P domain of the subtilisin-like proprotein convertases and other proteases	177
2919592705	434	95.24	10	434	15	414	2.6e-66	218.6	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
2919592706	171	95.62	1	164	4	156	3.8e-63	206.6	COG4329	Uncharacterized membrane protein	160
2919592708	459	35.56	280	451	233	376	1.2e-90	77.4	COG4695	Phage portal protein BeeE	398
2919592708	459	65.68	28	298	32	297	1.2e-90	227.3	COG4695	Phage portal protein BeeE	398
2919592711	553	96.38	1	552	8	539	0.0e+00	455.6	COG4626	Phage terminase-like protein, large subunit, contains N-terminal HTH domain	546
2919592712	174	36.31	1	142	19	83	1.1e-12	43	COG3728	Phage terminase, small subunit	179
2919592713	105	52.9	12	102	41	122	1.0e-07	26.3	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2919592714	52	18.09	30	51	5	21	3.0e-03	11.5	COG1826	Sec-independent protein translocase protein TatA	94
2919592714	52	19.15	1	21	4	21	3.0e-03	6.4	COG1826	Sec-independent protein translocase protein TatA	94
2919592719	137	95.2	10	137	5	123	4.7e-12	40.9	COG3293	Transposase	124
2919592720	125	75.2	1	119	22	115	9.6e-11	35.4	COG3293	Transposase	124
2919592726	156	92.86	1	153	13	168	1.9e-22	74.6	COG3013	Uncharacterized protein YfbU, UPF0304 family	168
2919592728	74	48.92	1	73	1	68	6.8e-13	43.1	COG3415	Transposase	138
2919592729	50	13.79	1	37	195	226	2.5e-05	18.5	COG1802	DNA-binding transcriptional regulator, GntR family	230
2919592730	318	28.57	23	316	401	560	2.7e-16	54	COG2931	Ca2+-binding protein, RTX toxin-related	510
2919592734	150	29.33	13	137	20	102	4.4e-04	14.2	COG5486	Predicted metal-binding membrane protein	283
2919592735	136	35.43	17	130	59	137	1.5e-03	12.6	COG5634	Uncharacterized protein YukJ	223
2919592736	505	16.92	162	263	31	96	5.3e-30	16.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919592736	505	46.67	299	486	192	373	5.3e-30	92.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919592737	1057	99.32	1	1038	2	1024	0.0e+00	1332.6	COG3696	Cu/Ag efflux pump CusA	1027
2919592738	158	88.59	6	155	12	143	1.9e-42	138.9	COG3019	Uncharacterized conserved protein	149
2919592741	44	13.11	1	43	258	297	6.6e-09	30	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2919592742	131	99.22	1	131	1	128	1.9e-23	77.6	COG4530	Uncharacterized protein	129
2919592744	69	98.51	1	69	1	66	3.8e-35	114.4	COG1278	Cold shock protein, CspA family	67
2919592745	285	93.31	1	280	17	309	1.8e-47	148.9	COG1397	ADP-ribosylglycohydrolase	314
2919592747	329	78.79	185	327	24	127	1.5e-18	61.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919592751	192	80.63	8	190	12	165	1.1e-56	186.1	COG4420	Uncharacterized membrane protein	191
2919592752	122	67.05	13	74	9	67	1.2e-04	16.2	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2919592756	235	84.4	11	211	27	210	9.6e-25	81.8	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919592759	272	85.6	16	133	6	112	5.5e-33	67.9	COG3293	Transposase	124
2919592759	272	97.6	143	267	1	122	5.5e-33	45.6	COG3293	Transposase	124
2919592761	235	53.88	2	230	195	423	9.0e-46	151.1	COG0840	Methyl-accepting chemotaxis protein	408
2919592763	58	34.88	2	56	40	69	1.7e-03	12.6	COG3978	Acetolactate synthase small subunit, contains ACT domain	86
2919592766	167	93.24	1	147	5	142	1.5e-47	155.7	COG4957	Predicted transcriptional regulator	148
2919592770	63	34.29	2	57	16	39	5.8e-04	14.5	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2919592780	245	73.84	1	201	1	175	3.5e-36	119.3	COG3416	Uncharacterized protein	233
2919592781	177	68.45	1	149	49	176	8.7e-35	114.7	COG4185	Predicted ABC-type ATPase	187
2919592783	263	70.66	9	263	68	238	4.6e-61	201.6	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2919592784	242	22.12	50	157	43	90	4.2e-11	9.6	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2919592784	242	32.72	144	242	141	211	4.2e-11	26.5	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2919592785	681	99.33	46	677	4	597	0.0e+00	751.1	COG0322	Excinuclease UvrABC, nuclease subunit	581
2919592786	199	93.81	2	197	9	190	2.4e-48	158	COG0558	Phosphatidylglycerophosphate synthase	192
2919592787	83	98.81	1	83	2	84	8.3e-21	67.9	COG1977	Molybdopterin converting factor, small subunit	84
2919592788	320	96.07	2	319	12	304	2.9e-91	298.9	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
2919592790	592	98.99	12	584	4	589	0.0e+00	512.1	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2919592791	346	99.04	4	346	2	311	1.0e-86	284.3	COG2017	Galactose mutarotase or related enzyme	308
2919592792	127	11.91	1	127	819	929	2.0e-38	125.7	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2919592793	47	7.11	3	39	323	350	2.0e-03	10.3	COG4214	ABC-type xylose transport system, permease component	394
2919592794	497	19.6	3	174	61	189	8.7e-23	1.5	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
2919592794	497	35.56	219	449	268	501	8.7e-23	65.4	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
2919592796	435	95.78	7	400	14	399	2.3e-100	329.3	COG3562	Capsule polysaccharide modification protein KpsS	403
2919592797	255	86.04	1	247	7	234	2.5e-45	147.9	COG0300	Short-chain dehydrogenase	265
2919592799	550	99.44	4	532	3	534	0.0e+00	598.6	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2919592801	297	72.98	33	254	65	272	2.1e-45	148.3	COG1864	DNA/RNA endonuclease G, NUC1	281
2919592803	31	11.4	1	31	1	31	9.8e-13	41.2	COG2894	Septum formation inhibitor-activating ATPase MinD	272
2919592805	505	85.4	4	433	36	380	5.3e-50	163.8	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2919592806	453	46.21	263	452	17	193	8.0e-29	14.9	COG0477	MFS family permease	338
2919592806	453	73.11	10	295	2	281	8.0e-29	83.5	COG0477	MFS family permease	338
2919592808	383	96.27	44	377	9	292	6.3e-26	84.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919592818	119	67.05	10	71	9	67	4.4e-05	16.2	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2919592824	179	51.77	2	135	35	151	2.9e-20	63.5	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2919592827	201	81.25	28	152	7	110	1.4e-05	17.7	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
2919592829	104	32.76	18	104	17	92	9.9e-29	93.6	COG1802	DNA-binding transcriptional regulator, GntR family	230
2919592830	72	12.47	2	68	275	332	9.9e-06	17.6	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2919592832	240	95.49	1	240	11	243	5.5e-47	153.8	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
2919592835	563	21.59	337	450	22	97	9.3e-12	22.2	COG1566	Multidrug resistance efflux pump	352
2919592835	563	27.56	423	556	185	281	9.3e-12	23.2	COG1566	Multidrug resistance efflux pump	352
2919592837	567	92.68	1	567	17	586	0.0e+00	656.8	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
2919592838	334	82.05	1	333	56	375	8.1e-34	110.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919592840	31	7.83	1	31	1	30	2.4e-08	26.3	COG0045	Succinyl-CoA synthetase, beta subunit	387
2919592841	310	99.03	1	306	2	306	1.7e-70	231	COG0223	Methionyl-tRNA formyltransferase	307
2919592842	41	7.48	1	32	371	400	2.3e-05	16.8	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2919592843	416	77.16	1	130	29	153	1.8e-25	82.4	COG3666	Transposase	161
2919592844	462	79.48	1	462	79	539	0.0e+00	668.1	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2919592845	419	86.87	72	416	37	327	1.0e-19	63.1	COG0582	Integrase	309
2919592846	414	41.78	228	411	47	206	2.3e-23	35.7	COG0477	MFS family permease	338
2919592846	414	67.1	2	262	17	273	2.3e-23	45.2	COG0477	MFS family permease	338
2919592847	283	87.68	7	258	23	271	1.7e-30	99.4	COG2801	Transposase InsO and inactivated derivatives	232
2919592848	91	61.54	7	90	22	93	8.7e-08	25.7	COG2963	Transposase and inactivated derivatives	116
2919592849	367	56.62	1	367	19	373	0.0e+00	516	COG1154	Deoxyxylulose-5-phosphate synthase	627
2919592850	352	83.13	7	252	41	247	1.4e-37	122.7	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2919592851	370	74.53	8	370	24	377	9.6e-67	219	COG5361	Uncharacterized conserved protein	458
2919592855	121	31.33	1	121	263	382	3.5e-51	167.2	COG0045	Succinyl-CoA synthetase, beta subunit	387
2919592856	226	75.85	1	226	1	223	6.2e-102	334	COG0074	Succinyl-CoA synthetase, alpha subunit	293
2919592857	340	86.62	1	340	30	372	0.0e+00	454.4	COG3328	Transposase (or an inactivated derivative)	379
2919592858	334	73.59	1	334	81	367	3.0e-24	78.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
