gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
648928564	172	24.08	11	169	4	191	4.0e-13	67.8	COG4734	Antirestriction protein	193
648928566	507	44.38	89	247	1	157	5.0e-28	119	COG3436	Transposase	157
648928574	326	25.39	110	302	58	231	1.0e-11	64.2	COG2801	Transposase InsO and inactivated derivatives	232
648928575	365	45.94	7	354	2	338	9.0e-113	400	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
648928576	221	39.89	45	219	47	228	3.0e-36	144	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
648928577	572	17.1	18	560	1	456	6.0e-32	132	COG0277	FAD/FMN-containing dehydrogenase	459
648928578	429	30.67	10	425	23	467	6.0e-71	261	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
648928580	369	26.77	28	338	1	308	1.0e-36	147	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648928581	129	31.2	3	126	1	120	1.0e-11	62.4	COG3293	Transposase	124
648928582	115	24.56	2	108	1	110	4.0e-11	60.1	COG3293	Transposase	124
648928583	148	34.4	1	123	2	126	1.0e-19	89.3	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648928584	203	34.31	1	202	1	204	1.0e-20	93	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
648928586	435	55.13	1	419	1	414	0.0e+00	558	COG1004	UDP-glucose 6-dehydrogenase	414
648928587	249	49.23	45	239	31	216	1.0e-59	222	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
648928588	147	54.17	4	147	2	145	3.0e-52	197	COG0757	3-dehydroquinate dehydratase	146
648928591	47	63.04	1	46	1	46	4.0e-11	59.9	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
648928592	737	39.55	23	725	5	708	0.0e+00	570	COG2217	Cation transport ATPase	713
648928593	170	31.37	14	166	13	159	6.0e-19	87	COG5456	Nitrogen fixation protein FixH	166
648928597	293	30.08	97	217	35	146	6.0e-10	58.4	COG2010	Cytochrome c, mono- and diheme variants	150
648928598	53	32.65	5	53	1	49	5.0e-06	42.9	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
648928599	244	61.86	5	240	1	227	1.0e-94	339	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
648928600	544	66.74	63	542	2	482	0.0e+00	677	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
648928601	352	28.61	6	338	5	342	7.0e-33	134	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
648928602	235	28.5	7	215	1	208	6.0e-19	88	COG0625	Glutathione S-transferase	211
648928603	474	34.03	30	460	7	414	2.0e-104	373	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
648928604	237	30.77	39	226	27	213	1.0e-28	120	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
648928607	198	41.92	1	196	1	198	8.0e-49	186	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
648928609	386	41.76	28	385	29	391	1.0e-94	339	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
648928610	1174	25.65	1	533	2	492	1.0e-63	238	COG0591	Na+/proline symporter	493
648928611	228	40.29	6	208	1	205	6.0e-45	173	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
648928615	551	31.52	58	545	1	442	2.0e-76	280	COG1793	ATP-dependent DNA ligase	444
648928619	338	24.02	22	332	45	427	5.0e-44	171	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
648928622	835	32.94	5	834	7	802	0.0e+00	771	COG1201	Lhr-like helicase	814
648928623	245	37.77	22	245	2	232	9.0e-46	177	COG1407	Metallophosphoesterase superfamily enzyme	235
648928625	309	29.37	8	293	1	256	6.0e-14	72	COG0730	Uncharacterized membrane protein YfcA	258
648928627	156	32.54	29	152	1	124	3.0e-13	68.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
648928629	598	33.26	34	456	5	387	2.0e-70	260	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648928630	212	27.36	4	197	1	199	7.0e-21	94.1	COG0625	Glutathione S-transferase	211
648928631	402	36.99	1	402	1	392	3.0e-77	282	COG0183	Acetyl-CoA acetyltransferase	392
648928632	127	20.37	1	106	10	116	1.0e-08	52	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
648928633	738	44.6	325	609	2	286	7.0e-87	315	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
648928634	345	34.17	219	337	6	124	1.0e-15	77.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
648928636	354	31.08	38	319	2	296	4.0e-57	215	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
648928637	446	27.05	1	446	2	451	3.0e-50	192	COG0534	Na+-driven multidrug efflux pump	455
648928638	364	40.81	45	357	1	309	7.0e-85	307	COG0167	Dihydroorotate dehydrogenase	310
648928639	143	57.14	30	141	3	114	2.0e-37	147	COG3502	Uncharacterized conserved protein, DUF952 family	115
648928641	218	34.23	1	218	1	211	7.0e-27	114	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
648928643	611	28.25	196	584	1	396	8.0e-32	132	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
648928645	564	37.87	34	558	1	521	0.0e+00	571	COG1384	Lysyl-tRNA synthetase, class I	521
648928647	358	23.51	56	305	26	274	2.0e-07	50.4	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
648928648	130	56.56	2	123	1	122	7.0e-44	169	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
648928649	203	23.71	14	203	1	191	1.0e-08	53.1	COG0558	Phosphatidylglycerophosphate synthase	192
648928652	398	45.45	6	398	1	395	0.0e+00	462	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
648928653	366	21.52	142	364	1	182	5.0e-31	128	COG0717	Deoxycytidine triphosphate deaminase	183
648928654	182	32.97	1	182	2	185	7.0e-37	146	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
648928658	614	27.07	190	583	11	401	5.0e-37	149	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
648928659	281	27.9	9	277	3	264	6.0e-26	111	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
648928660	216	41.59	1	213	1	211	6.0e-41	160	COG3571	Predicted hydrolase of the alpha/beta-hydrolase fold	213
648928662	468	25.58	98	376	50	342	3.0e-21	96.9	COG1566	Multidrug resistance efflux pump	352
648928664	325	37.46	12	325	1	281	2.0e-75	276	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
648928665	309	54.25	8	307	7	310	1.0e-116	413	COG0078	Ornithine carbamoyltransferase	310
648928666	401	53.75	7	390	17	399	0.0e+00	494	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
648928668	181	52.87	1	173	1	169	4.0e-46	177	COG5352	Uncharacterized protein	169
648928669	230	52.17	2	227	1	228	8.0e-63	233	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648928670	233	45.79	4	217	8	221	3.0e-42	165	COG0704	Phosphate uptake regulator	240
648928671	265	68.77	13	265	3	253	1.0e-129	455	COG1117	ABC-type phosphate transport system, ATPase component	253
648928672	446	39.25	183	446	35	292	2.0e-62	233	COG0581	ABC-type phosphate transport system, permease component	292
648928673	490	41.35	181	489	5	310	7.0e-68	251	COG0573	ABC-type phosphate transport system, permease component	310
648928674	345	22.69	4	330	20	315	2.0e-34	140	COG0226	ABC-type phosphate transport system, periplasmic component	318
648928677	163	18.63	1	159	4	149	1.0e-05	42.4	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
648928679	302	27.47	14	238	1	233	9.0e-21	94.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648928682	211	55.35	1	211	2	214	5.0e-82	297	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
648928684	322	33.62	2	312	4	351	2.0e-56	212	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
648928685	288	31.23	1	241	1	244	2.0e-27	116	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648928686	246	35.86	1	246	6	256	8.0e-44	170	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648928687	593	34.34	33	459	6	393	3.0e-70	260	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648928688	329	44.66	10	215	7	211	7.0e-58	217	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
648928689	309	47.44	1	307	2	310	4.0e-88	318	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
648928690	86	44.93	5	73	2	70	2.0e-10	56.9	COG1722	Exonuclease VII small subunit	81
648928691	385	40.98	321	381	3	63	1.0e-08	55	COG2771	DNA-binding transcriptional regulator, CsgD family	65
648928692	639	61.78	7	631	2	625	0.0e+00	933	COG1154	Deoxyxylulose-5-phosphate synthase	627
648928694	474	17.97	1	372	6	383	1.0e-05	45.2	COG2814	Predicted arabinose efflux permease, MFS family	394
648928696	183	43.62	11	159	7	151	4.0e-32	130	COG2847	Copper(I)-binding protein	151
648928697	422	33.18	5	403	6	432	3.0e-78	285	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
648928699	439	56.44	73	274	3	203	4.0e-73	268	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
648928701	295	39.15	71	294	3	234	2.0e-40	159	COG0412	Dienelactone hydrolase	236
648928703	373	57.85	14	371	1	355	0.0e+00	519	COG0082	Chorismate synthase	369
648928705	214	34.52	23	214	6	193	7.0e-33	134	COG0406	Broad specificity phosphatase PhoE	208
648928706	272	67.05	6	263	2	259	4.0e-119	421	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
648928707	474	39.48	10	471	2	457	6.0e-98	351	COG0277	FAD/FMN-containing dehydrogenase	459
648928712	487	37.68	12	483	1	408	1.0e-97	351	COG0593	Chromosomal replication initiation ATPase DnaA	408
648928713	205	29.63	53	187	10	134	6.0e-13	67.7	COG3415	Transposase	138
648928716	277	44.01	8	276	11	285	3.0e-67	248	COG4976	Predicted methyltransferase, contains TPR repeat	287
648928717	247	47.11	1	220	1	223	1.0e-63	236	COG2135	Putative SOS response-associated peptidase YedK	226
648928719	141	37.19	8	127	6	122	1.0e-20	92	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
648928720	92	40	1	90	37	126	1.0e-21	94.4	COG5451	Predicted secreted protein	128
648928722	214	21.95	4	205	3	203	2.0e-10	59.5	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
648928724	217	25.84	1	173	3	173	3.0e-17	81.9	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
648928725	419	53.58	12	416	15	411	3.0e-123	435	COG5379	S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase	414
648928726	413	22.7	2	167	47	231	9.0e-12	65.2	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
648928728	444	39.53	5	425	1	424	9.0e-122	430	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
648928729	298	31.91	1	298	11	304	3.0e-54	205	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
648928730	217	29.53	20	209	1	189	1.0e-29	123	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
648928731	168	46.2	1	158	15	172	4.0e-41	160	COG5350	Predicted protein tyrosine phosphatase	172
648928732	332	51.88	6	325	20	318	5.0e-94	337	COG4111	Uncharacterized conserved protein	322
648928734	175	25.9	27	163	13	150	1.0e-11	62.5	COG2862	Uncharacterized membrane protein YqhA	169
648928736	286	54.12	8	284	1	278	1.0e-96	346	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
648928737	534	49.51	19	525	9	517	0.0e+00	547	COG0029	Aspartate oxidase	518
648928738	360	53.35	53	359	12	323	7.0e-113	400	COG0379	Quinolinate synthase	324
648928739	408	20.86	50	396	49	386	2.0e-10	60.6	COG2814	Predicted arabinose efflux permease, MFS family	394
648928740	135	33.33	10	124	3	119	2.0e-15	74.6	COG3654	Prophage maintenance system killer protein	132
648928742	697	46.81	1	697	3	691	0.0e+00	780	COG0751	Glycyl-tRNA synthetase, beta subunit	691
648928743	543	34.58	13	515	142	641	3.0e-95	342	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
648928744	312	70.86	1	302	1	288	0.0e+00	527	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
648928747	285	34.06	4	279	45	317	1.0e-54	207	COG0616	Periplasmic serine protease, ClpP class	317
648928748	307	43.78	112	303	1	201	8.0e-44	170	COG1573	Uracil-DNA glycosylase	202
648928749	559	32.25	12	472	1	396	6.0e-75	275	COG0644	Dehydrogenase (flavoprotein)	396
648928752	436	43.27	1	436	28	470	2.0e-110	392	COG0513	Superfamily II DNA and RNA helicase	513
648928755	373	44.72	21	373	47	397	5.0e-82	298	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
648928756	114	25.51	5	100	1	98	1.0e-11	61.9	COG1605	Chorismate mutase	101
648928757	764	56.12	9	438	15	432	0.0e+00	570	COG0281	Malic enzyme	432
648928759	180	48.24	6	173	1	169	8.0e-53	199	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
648928761	378	46.26	59	352	1	289	9.0e-84	304	COG1533	DNA repair photolyase	297
648928762	216	52.43	32	212	1	185	3.0e-59	221	COG0164	Ribonuclease HII	199
648928763	159	34.64	5	157	10	161	4.0e-12	64.5	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
648928764	185	29.03	31	185	2	156	4.0e-17	81.5	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
648928766	249	39.44	1	246	3	244	5.0e-43	168	COG0356	FoF1-type ATP synthase, membrane subunit a	246
648928767	132	50.91	20	128	6	115	2.0e-22	98.5	COG5336	FoF1-type ATP synthase assembly protein I	116
648928768	1152	34.57	1	1149	1	1163	0.0e+00	571	COG1196	Chromosome segregation ATPase	1163
648928769	212	31.03	17	212	47	243	5.0e-24	104	COG1651	Protein-disulfide isomerase	244
648928771	177	35.19	13	174	23	179	8.0e-29	120	COG5389	Uncharacterized protein	181
648928772	370	46.42	21	366	12	340	2.0e-103	369	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
648928773	160	56.25	16	158	39	181	2.0e-39	154	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
648928774	161	56.69	1	157	1	157	9.0e-54	202	COG2193	Bacterioferritin (cytochrome b1)	157
648928775	503	24.62	223	481	1	233	6.0e-41	162	COG0775	Nucleoside phosphorylase	234
648928777	268	29.26	1	263	1	265	3.0e-34	138	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
648928778	265	40.35	35	262	10	220	1.0e-46	179	COG0765	ABC-type amino acid transport system, permease component	222
648928781	372	36.46	17	296	14	297	4.0e-62	232	COG0863	DNA modification methylase	302
648928784	204	28.16	1	203	8	207	1.0e-23	103	COG0625	Glutathione S-transferase	211
648928787	216	55.36	42	209	33	199	1.0e-60	226	COG3738	Uncharacterized protein YijF, DUF1287 family	200
648928788	426	43.2	16	423	2	398	5.0e-113	401	COG0162	Tyrosyl-tRNA synthetase	401
648928789	603	40.33	415	595	4	181	2.0e-36	147	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
648928791	245	32.08	1	245	1	265	6.0e-32	131	COG3329	Uncharacterized conserved protein	372
648928795	298	27.76	4	281	1	280	3.0e-28	119	COG0583	DNA-binding transcriptional regulator, LysR family	297
648928797	530	45.45	33	522	5	489	0.0e+00	550	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
648928798	448	41.45	1	448	10	449	0.0e+00	478	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
648928799	160	20	4	151	6	139	6.0e-14	70.4	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
648928800	123	57.02	4	122	10	130	8.0e-37	145	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
648928801	383	43.52	6	379	1	376	2.0e-98	353	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
648928803	332	55.07	10	305	1	292	4.0e-109	388	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
648928804	321	38.6	1	321	5	330	3.0e-72	265	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
648928805	150	65.99	5	148	2	148	3.0e-53	200	COG0328	Ribonuclease HI	154
648928806	284	31.11	6	269	4	272	2.0e-39	156	COG1597	Diacylglycerol kinase family enzyme	301
648928808	201	31.55	14	180	3	169	1.0e-22	99.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648928809	428	35.14	1	412	15	438	4.0e-90	325	COG0612	Predicted Zn-dependent peptidase	438
648928810	468	30.19	1	460	1	411	2.0e-97	349	COG0498	Threonine synthase	411
648928811	198	43.94	1	198	4	194	6.0e-59	220	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
648928812	297	25.47	29	288	8	268	1.0e-28	120	COG4233	Thiol-disulfide interchange protein, contains DsbC and DsbD domains	273
648928813	160	43.64	1	160	1	165	6.0e-45	173	COG0678	Peroxiredoxin	165
648928814	259	35.14	1	258	1	246	7.0e-43	167	COG3346	Cytochrome oxidase assembly protein ShyY1	252
648928815	125	49.59	1	123	4	126	1.0e-38	151	COG5349	Uncharacterized conserved protein, DUF983 family	126
648928816	288	41.12	75	287	8	207	2.0e-47	183	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
648928817	202	51.04	9	199	4	195	7.0e-65	240	COG3175	Cytochrome c oxidase assembly protein Cox11	195
648928819	339	51.38	47	335	15	300	1.0e-89	323	COG0109	Polyprenyltransferase (heme O synthase)	304
648928820	531	60.15	12	530	3	517	0.0e+00	597	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
648928822	315	31.99	24	292	4	234	1.0e-51	197	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
648928823	189	40.68	17	189	3	178	2.0e-40	158	COG5342	Invasion protein IalB, involved in pathogenesis	181
648928824	570	42.43	3	399	1	397	4.0e-62	232	COG0475	Kef-type K+ transport system, membrane component KefB	397
648928825	474	40.6	16	472	2	454	2.0e-120	425	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
648928827	73	67.65	1	68	2	68	6.0e-23	98.9	COG3908	Uncharacterized protein	77
648928828	341	36.9	3	332	5	329	7.0e-77	281	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
648928829	427	43.27	11	422	4	419	1.0e-114	406	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
648928830	222	38.68	2	213	12	214	3.0e-50	191	COG2121	Uncharacterized conserved protein, lysophospholipid acyltransferase (LPLAT) superfamily	214
648928832	270	34.58	15	242	3	240	4.0e-45	175	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
648928833	447	35.03	14	447	5	454	3.0e-82	299	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
648928835	405	40	207	376	10	178	3.0e-38	153	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
648928836	314	40.27	19	310	1	289	2.0e-54	206	COG0382	4-hydroxybenzoate polyprenyltransferase	289
648928837	422	58.35	1	421	1	424	0.0e+00	572	COG0151	Phosphoribosylamine-glycine ligase	428
648928838	308	25.9	33	306	17	281	8.0e-23	101	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648928841	280	32.08	1	277	7	297	9.0e-44	170	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
648928844	185	47.85	1	182	2	184	1.0e-53	202	COG0742	16S rRNA G966 N2-methylase RsmD	187
648928845	380	43.15	14	255	1	248	6.0e-61	228	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
648928846	262	54.93	117	257	11	152	3.0e-47	182	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
648928848	630	43.8	11	629	3	637	0.0e+00	639	COG0323	DNA mismatch repair ATPase MutL	638
648928849	290	32.46	12	276	1	260	1.0e-54	207	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
648928850	223	25.29	81	213	48	213	2.0e-06	46.5	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
648928852	150	33.1	7	143	13	157	5.0e-22	97.1	COG2030	Acyl dehydratase	159
648928854	332	43.93	11	315	3	303	7.0e-84	304	COG0196	FAD synthase	304
648928859	986	43.39	8	979	2	932	0.0e+00	1068	COG0060	Isoleucyl-tRNA synthetase	933
648928860	176	37.82	22	176	12	165	3.0e-26	111	COG0597	Lipoprotein signal peptidase	167
648928862	471	32.05	32	470	1	438	2.0e-83	303	COG0612	Predicted Zn-dependent peptidase	438
648928863	442	29.17	19	442	3	434	5.0e-68	251	COG0612	Predicted Zn-dependent peptidase	438
648928864	503	25.5	243	485	3	244	4.0e-26	113	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
648928866	499	42.11	22	494	13	454	6.0e-119	421	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
648928869	95	68.09	1	94	1	94	2.0e-34	136	COG0234	Co-chaperonin GroES (HSP10)	96
648928870	546	49.91	1	534	1	523	0.0e+00	500	COG0459	Chaperonin GroEL (HSP60 family)	524
648928871	234	32.55	21	227	2	201	9.0e-36	143	COG0625	Glutathione S-transferase	211
648928872	70	38.03	1	70	2	72	6.0e-07	45.7	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
648928875	154	54.26	23	151	6	134	2.0e-43	168	COG1607	Acyl-CoA hydrolase	157
648928878	162	33.9	28	144	16	133	3.0e-18	84.6	COG2346	Truncated hemoglobin YjbI	133
648928879	138	35.71	1	138	1	139	3.0e-24	104	COG1959	DNA-binding transcriptional regulator, IscR family	150
648928885	272	18.73	9	271	3	251	5.0e-06	45.3	COG3394	Predicted glycoside hydrolase or deacetylase ChbG, UPF0249 family	257
648928887	379	26.49	21	322	4	288	9.0e-18	84.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
648928889	551	30.21	7	528	1	429	2.0e-101	363	COG0124	Histidyl-tRNA synthetase	429
648928890	378	38.2	8	378	25	389	2.0e-49	190	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
648928891	321	31.8	2	302	1	286	2.0e-46	180	COG0040	ATP phosphoribosyltransferase	290
648928892	219	56.68	25	210	4	188	3.0e-70	258	COG2818	3-methyladenine DNA glycosylase Tag	188
648928895	261	44.79	107	261	67	229	7.0e-36	144	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
648928897	443	31.12	15	428	1	387	1.0e-73	270	COG0247	Fe-S oxidoreductase	388
648928898	395	23.67	2	391	33	455	3.0e-44	172	COG0277	FAD/FMN-containing dehydrogenase	459
648928899	498	40.69	23	474	1	459	1.0e-98	353	COG0277	FAD/FMN-containing dehydrogenase	459
648928900	316	30.23	5	299	2	297	2.0e-39	156	COG0583	DNA-binding transcriptional regulator, LysR family	297
648928901	131	50	1	128	7	134	4.0e-37	146	COG3474	Cytochrome c2	135
648928902	463	50.24	38	460	7	424	2.0e-109	389	COG4949	Uncharacterized membrane-anchored protein	424
648928903	249	39.21	14	237	19	241	7.0e-41	160	COG2186	DNA-binding transcriptional regulator, FadR family	241
648928904	378	40.32	7	378	1	350	6.0e-101	361	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
648928905	232	36.14	1	200	1	198	3.0e-35	142	COG0518	GMP synthase - Glutamine amidotransferase domain	198
648928909	291	34.13	2	281	1	291	3.0e-32	132	COG0583	DNA-binding transcriptional regulator, LysR family	297
648928913	457	60.18	1	457	1	456	0.0e+00	615	COG3572	Gamma-glutamylcysteine synthetase	456
648928914	573	36.46	393	572	44	213	3.0e-30	126	COG2114	Adenylate cyclase, class 3	227
648928915	252	39.04	6	250	1	246	4.0e-58	217	COG1385	16S rRNA U1498 N3-methylase RsmE	246
648928917	524	41.68	6	489	1	431	6.0e-130	458	COG1570	Exonuclease VII, large subunit	440
648928918	147	36.36	27	147	12	116	1.0e-09	55.7	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
648928919	456	29.34	67	456	7	379	4.0e-52	199	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648928920	222	27.97	36	178	12	152	3.0e-14	71.9	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648928921	337	23.15	1	334	1	332	4.0e-27	115	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648928922	461	46.55	1	454	1	461	0.0e+00	482	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
648928923	602	36.94	3	578	4	600	4.0e-120	425	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
648928924	345	43.82	13	345	2	340	8.0e-73	267	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648928926	162	53.57	21	160	46	181	2.0e-29	122	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
648928929	910	32.93	3	645	1	598	1.0e-88	321	COG1042	Acyl-CoA synthetase (NDP forming)	598
648928930	568	34.12	17	565	2	550	0.0e+00	484	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
648928935	244	32.57	25	241	13	227	2.0e-30	125	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
648928936	275	30.63	11	275	5	256	1.0e-08	53.9	COG0730	Uncharacterized membrane protein YfcA	258
648928939	177	38.71	52	175	32	155	1.0e-12	66.2	COG5490	Uncharacterized protein	158
648928940	332	30.91	3	328	2	302	2.0e-58	219	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
648928941	302	51.59	21	302	9	290	5.0e-83	300	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
648928943	223	33.17	13	219	21	226	2.0e-24	106	COG1802	DNA-binding transcriptional regulator, GntR family	230
648928944	345	33.33	1	339	1	331	4.0e-66	245	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
648928945	456	20	46	455	21	429	5.0e-19	89.3	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648928947	382	39.32	149	382	52	281	4.0e-51	195	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648928948	363	53.65	1	356	1	338	1.0e-122	432	COG3839	ABC-type sugar transport system, ATPase component	338
648928949	262	33.47	8	246	4	242	1.0e-54	206	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
648928950	357	49.85	13	337	3	336	3.0e-107	381	COG3839	ABC-type sugar transport system, ATPase component	338
648928951	427	29.13	1	426	6	433	7.0e-40	158	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648928952	295	39.66	2	291	1	290	1.0e-54	207	COG1175	ABC-type sugar transport system, permease component	295
648928953	273	39.29	1	273	2	281	3.0e-49	188	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648928954	578	19.92	56	520	24	433	4.0e-18	87	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648928955	355	35.24	1	349	2	338	5.0e-81	294	COG3839	ABC-type sugar transport system, ATPase component	338
648928956	359	41.71	1	349	1	337	1.0e-95	343	COG3839	ABC-type sugar transport system, ATPase component	338
648928957	287	32.64	1	285	4	291	8.0e-45	174	COG1175	ABC-type sugar transport system, permease component	295
648928958	267	35.61	9	267	17	280	2.0e-45	176	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648928959	107	60.87	15	106	5	96	9.0e-19	85.1	COG5477	Predicted small integral membrane protein	97
648928960	298	28.3	4	298	1	297	3.0e-36	146	COG0524	Sugar or nucleoside kinase, ribokinase family	311
648928961	129	48.94	30	123	9	102	8.0e-24	102	COG1733	DNA-binding transcriptional regulator, HxlR family	120
648928962	194	31.84	3	194	2	188	5.0e-28	117	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
648928963	241	33.5	8	205	4	201	2.0e-35	143	COG0625	Glutathione S-transferase	211
648928964	253	41.1	38	253	6	223	2.0e-51	195	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
648928965	637	33.8	5	614	18	637	1.0e-111	397	COG1874	Beta-galactosidase GanA	673
648928966	203	33.5	1	203	10	211	2.0e-44	172	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
648928967	303	38.85	8	297	8	300	4.0e-61	228	COG3734	2-keto-3-deoxy-galactonokinase	306
648928968	254	32.41	7	251	2	251	7.0e-45	174	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648928969	695	30.72	25	644	22	655	2.0e-110	393	COG3345	Alpha-galactosidase	687
648928970	282	32.73	7	282	4	281	4.0e-51	195	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648928971	306	40.14	21	306	8	294	2.0e-54	206	COG1175	ABC-type sugar transport system, permease component	295
648928972	419	21.16	1	419	3	431	7.0e-36	145	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648928973	259	37.04	9	251	1	243	4.0e-51	194	COG1414	DNA-binding transcriptional regulator, IclR family	246
648928974	369	52.87	17	363	1	338	1.0e-122	433	COG3839	ABC-type sugar transport system, ATPase component	338
648928975	425	44.22	21	415	1	388	8.0e-122	430	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
648928977	178	35.22	25	174	20	173	2.0e-24	105	COG1443	Isopentenyldiphosphate isomerase	185
648928980	419	27.68	5	392	8	407	6.0e-32	131	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
648928981	536	36.26	168	512	121	473	3.0e-80	292	COG0069	Glutamate synthase domain 2	485
648928982	658	36.07	118	656	1	533	9.0e-124	437	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
648928985	357	25.74	240	338	4	104	6.0e-15	75.4	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
648928988	420	54.87	1	418	2	422	3.0e-126	445	COG2379	Glycerate-2-kinase	422
648928989	438	35.6	57	437	8	379	2.0e-63	236	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648928991	344	23.26	1	338	1	331	2.0e-28	119	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648928992	511	39.03	4	503	13	526	3.0e-113	402	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648928993	424	27.14	24	416	3	387	9.0e-45	174	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648928994	267	27.07	12	258	18	282	8.0e-27	114	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648928995	348	20.53	22	346	17	380	1.0e-11	64.6	COG2309	Leucyl aminopeptidase (aminopeptidase T)	385
648928996	158	31.3	40	154	12	126	3.0e-12	64.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
648928997	290	42.51	1	284	3	287	2.0e-65	242	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
648928998	424	40.69	46	421	1	375	2.0e-70	260	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648928999	166	25.97	10	163	15	165	3.0e-15	75	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648929000	330	31.53	1	330	1	329	4.0e-57	215	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648929001	97	37.11	1	97	2	96	2.0e-21	94.2	COG5470	Uncharacterized conserved protein, DUF1330 family	96
648929003	436	30.77	9	429	2	408	7.0e-62	231	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648929004	490	32.12	1	490	8	554	1.0e-80	294	COG0747	ABC-type transport system, periplasmic component	556
648929005	315	43.53	1	315	1	317	9.0e-81	293	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648929006	275	45.99	1	272	15	288	2.0e-62	232	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648929007	537	52.61	1	521	3	536	0.0e+00	601	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
648929008	483	44.11	15	479	3	466	6.0e-123	434	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648929009	247	41.57	1	245	1	250	5.0e-43	168	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648929010	308	31.65	21	297	4	279	2.0e-50	192	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
648929011	168	27.1	1	155	1	155	9.0e-15	73.4	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648929012	426	46.58	45	424	1	379	2.0e-84	306	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648929013	345	31.69	1	337	2	332	1.0e-60	227	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648929016	1139	30.64	623	1134	1	530	3.0e-79	290	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648929017	93	38.46	7	84	11	88	7.0e-15	72	COG4298	Uncharacterized protein	95
648929018	234	25.34	4	223	6	223	7.0e-09	54.5	COG1842	Phage shock protein A	225
648929019	196	25.86	1	173	2	175	2.0e-07	48.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648929021	370	32.76	18	364	3	311	4.0e-45	175	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
648929022	316	24.53	1	315	4	322	4.0e-32	132	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
648929023	338	35.33	3	332	1	332	3.0e-74	272	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
648929024	385	26.82	1	381	1	342	4.0e-44	172	COG0673	Predicted dehydrogenase	342
648929025	297	24.73	5	271	1	252	1.0e-27	117	COG1082	Sugar phosphate isomerase/epimerase	274
648929026	374	30.68	11	374	1	340	6.0e-53	201	COG0673	Predicted dehydrogenase	342
648929027	622	48.79	4	621	3	617	0.0e+00	684	COG3962	TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism	617
648929028	324	28.84	10	319	1	311	9.0e-41	161	COG0524	Sugar or nucleoside kinase, ribokinase family	311
648929029	280	27.86	14	268	19	267	2.0e-33	136	COG3718	5-deoxy-D-glucuronate isomerase	270
648929030	279	35.66	1	278	1	285	2.0e-57	216	COG0191	Fructose/tagatose bisphosphate aldolase	286
648929031	329	32.75	1	329	2	340	6.0e-57	214	COG0673	Predicted dehydrogenase	342
648929034	118	44.14	1	111	2	111	2.0e-26	111	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648929035	791	27.22	8	785	74	860	0.0e+00	685	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
648929039	644	31.06	146	641	180	650	1.0e-62	234	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
648929040	413	25.59	1	412	2	381	2.0e-35	143	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648929041	325	23.85	1	324	4	328	4.0e-39	155	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648929043	437	31.03	54	429	3	376	4.0e-62	232	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648929045	149	27.97	18	135	3	120	2.0e-08	51.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
648929047	1040	31.2	724	978	3	265	4.0e-38	154	COG1018	Ferredoxin-NADP reductase	266
648929048	325	45.19	2	312	8	319	4.0e-78	285	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
648929049	229	32.87	1	216	15	225	6.0e-30	124	COG1802	DNA-binding transcriptional regulator, GntR family	230
648929050	283	47.81	10	278	1	263	1.0e-79	289	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
648929057	546	32.12	144	279	16	147	2.0e-14	74.5	COG5616	TolB amino-terminal domain (function unknown)	152
648929060	330	45.43	5	320	2	266	4.0e-93	334	COG4608	ABC-type oligopeptide transport system, ATPase component	309
648929061	336	55.49	6	321	1	316	6.0e-118	417	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
648929062	324	42.16	19	324	1	287	2.0e-65	242	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648929063	323	43.34	1	322	1	317	2.0e-80	292	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648929065	528	27.9	4	528	20	554	9.0e-76	277	COG0747	ABC-type transport system, periplasmic component	556
648929068	132	28.81	3	114	2	116	3.0e-10	57.8	COG3293	Transposase	124
648929069	118	29.82	3	116	11	120	1.0e-05	42	COG3293	Transposase	124
648929071	263	38.33	13	248	13	251	1.0e-41	163	COG1484	DNA replication protein DnaC	254
648929072	506	28.15	2	269	7	257	4.0e-17	83.2	COG4584	Transposase	278
648929073	322	68.2	72	310	1	239	1.0e-104	373	COG1186	Protein chain release factor B	239
648929074	405	35.55	198	402	64	273	1.0e-32	134	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
648929075	278	47.92	12	276	4	265	2.0e-80	292	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
648929076	155	57.42	1	155	1	155	8.0e-55	205	COG1225	Peroxiredoxin	157
648929078	417	48.04	12	417	9	401	2.0e-124	439	COG0162	Tyrosyl-tRNA synthetase	401
648929080	325	25.47	1	323	5	373	1.0e-26	113	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648929081	65	33.33	1	65	3	68	3.0e-10	57.1	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
648929082	258	52.71	1	258	7	262	1.0e-97	349	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
648929083	202	37.06	5	201	16	210	8.0e-45	173	COG0352	Thiamine monophosphate synthase	211
648929089	469	47.37	2	469	1	443	0.0e+00	522	COG0174	Glutamine synthetase	443
648929090	113	71.43	2	113	1	112	3.0e-38	149	COG0347	Nitrogen regulatory protein PII	112
648929091	514	42.2	228	501	9	284	1.0e-58	221	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
648929102	186	34.33	1	183	2	202	7.0e-20	90.2	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
648929107	3659	24.71	1603	1772	2	163	3.0e-18	90.1	COG4935	Regulatory P domain of the subtilisin-like proprotein convertases and other proteases	177
648929109	205	29.63	53	187	10	134	6.0e-13	67.7	COG3415	Transposase	138
648929115	390	25.77	1	383	4	317	3.0e-40	159	COG0270	Site-specific DNA-cytosine methylase	328
648929124	482	44.38	89	247	1	157	8.0e-28	118	COG3436	Transposase	157
648929130	467	44.38	89	247	1	157	3.0e-28	120	COG3436	Transposase	157
648929140	402	28.44	70	393	55	381	9.0e-22	98.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648929144	431	43.32	8	254	3	242	1.0e-73	270	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
648929145	272	37.15	19	271	12	262	1.0e-35	143	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
648929151	369	36.29	9	366	6	371	3.0e-77	282	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
648929152	592	22.65	192	580	5	374	3.0e-24	107	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648929153	387	28.18	31	383	22	377	7.0e-31	128	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648929154	355	28.53	18	354	2	313	3.0e-46	179	COG0451	Nucleoside-diphosphate-sugar epimerase	314
648929155	612	28.86	1	599	1	500	3.0e-99	356	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
648929156	426	41.43	6	418	9	424	2.0e-124	439	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
648929163	189	40.89	7	189	3	205	1.0e-30	126	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
648929165	963	48.89	607	920	1	311	2.0e-102	367	COG4644	Transposase and inactivated derivatives, TnpA family	323
648929168	630	42.26	9	620	1	585	0.0e+00	519	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
648929169	340	39.42	1	333	5	340	1.0e-71	263	COG5397	Uncharacterized protein	349
648929170	401	31.18	114	390	3	259	3.0e-48	186	COG1192	Cellulose biosynthesis protein BcsQ	259
648929171	361	28.5	86	296	1	199	1.0e-16	81.1	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
648929177	158	33.7	64	150	7	94	1.0e-08	52.9	COG1669	Predicted nucleotidyltransferase	97
648929178	123	34.69	1	98	3	96	2.0e-19	87.7	COG2361	Uncharacterized conserved protein, contains HEPN domain	117
648929180	337	33.92	1	335	1	325	7.0e-57	214	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
648929181	96	37.04	1	81	1	81	3.0e-17	80	COG1359	Quinol monooxygenase YgiN	100
648929182	223	29.96	1	221	1	227	6.0e-27	114	COG0583	DNA-binding transcriptional regulator, LysR family	297
648929184	396	36.92	185	394	12	225	1.0e-47	184	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
648929192	205	29.63	53	187	10	134	6.0e-13	67.7	COG3415	Transposase	138
648929193	469	44.38	89	247	1	157	3.0e-28	119	COG3436	Transposase	157
648929199	407	70.17	1	407	3	410	0.0e+00	670	COG2871	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF	410
648929200	202	70.79	1	202	1	198	1.0e-71	262	COG2209	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE	198
648929201	217	70.65	6	206	8	208	1.0e-81	296	COG1347	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD	208
648929202	273	46.46	25	272	8	260	3.0e-72	265	COG2869	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC	264
648929203	402	57.5	2	397	1	399	1.0e-115	409	COG1805	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB	400
648929204	447	48.43	5	447	3	447	0.0e+00	471	COG1726	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA	447
648929205	341	36.76	4	339	1	335	6.0e-80	291	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
648929209	203	34.31	1	202	1	204	1.0e-20	93	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
648929210	148	34.4	1	123	2	126	1.0e-19	89.3	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648929211	115	24.56	2	108	1	110	4.0e-11	60.1	COG3293	Transposase	124
648929212	129	30.4	3	126	1	120	3.0e-11	60.9	COG3293	Transposase	124
648929213	457	41.44	9	448	1	438	8.0e-97	348	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
648929214	211	67.18	11	205	2	196	5.0e-80	290	COG0740	ATP-dependent protease ClpP, protease subunit	200
648929215	431	73.83	26	428	1	405	0.0e+00	716	COG1219	ATP-dependent protease Clp, ATPase subunit	408
648929216	809	68.56	14	785	7	782	0.0e+00	1205	COG0466	ATP-dependent Lon protease, bacterial type	782
648929218	91	60.44	1	91	2	92	1.0e-27	114	COG0776	Bacterial nucleoid DNA-binding protein	94
648929220	358	23.6	104	342	49	288	2.0e-06	47.1	COG4974	Site-specific recombinase XerD	300
648929224	64	39.34	1	61	2	61	3.0e-09	53.3	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
648929236	109	44.86	1	107	1	107	4.0e-30	122	COG1733	DNA-binding transcriptional regulator, HxlR family	120
648929241	326	25.39	110	302	58	231	8.0e-12	64.6	COG2801	Transposase InsO and inactivated derivatives	232
648929244	373	25.07	1	327	5	339	8.0e-32	131	COG3500	Phage protein D	350
648929246	508	44.38	89	247	1	157	2.0e-28	120	COG3436	Transposase	157
648929250	262	35.53	1	144	4	152	3.0e-20	92.3	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
648929256	249	28.57	3	115	2	117	1.0e-09	57	COG3293	Transposase	124
648929264	508	44.38	89	247	1	157	2.0e-28	120	COG3436	Transposase	157
648929266	348	33.45	1	268	2	225	1.0e-35	144	COG4422	Bacteriophage protein gp37	250
648929272	121	52.89	1	121	1	121	3.0e-33	133	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
648929273	193	66.27	25	193	1	168	7.0e-76	276	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
648929274	201	53.37	1	177	2	176	2.0e-52	198	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
648929275	394	60.66	1	394	7	398	0.0e+00	636	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
648929276	468	46.3	14	175	3	160	3.0e-53	202	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
648929277	319	60.13	1	298	5	303	0.0e+00	475	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
648929279	688	48.07	1	688	1	690	0.0e+00	749	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
648929280	350	49.71	1	346	1	332	5.0e-96	344	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
648929282	162	45.78	1	162	1	161	9.0e-49	185	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
648929283	204	46.24	1	173	1	166	4.0e-27	114	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
648929284	102	63	3	102	2	100	5.0e-21	92.5	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
648929285	671	44.07	5	659	1	606	0.0e+00	509	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
648929286	506	55.4	2	498	1	496	0.0e+00	572	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
648929287	479	47.79	7	479	2	475	9.0e-108	384	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
648929288	258	37.29	24	254	4	235	7.0e-50	190	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
648929289	558	38.78	5	555	4	554	0.0e+00	500	COG0595	mRNA degradation ribonuclease J1/J2	555
648929291	87	43.68	1	86	1	86	1.0e-15	75	COG5454	Predicted secreted protein	89
648929292	443	40.72	1	439	1	500	6.0e-128	451	COG0442	Prolyl-tRNA synthetase	500
648929293	433	44.6	20	433	1	408	2.0e-110	393	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
648929294	243	44.34	20	239	1	220	9.0e-72	263	COG1136	ABC-type lipoprotein export system, ATPase component	226
648929295	1159	47.33	18	1157	2	1139	0.0e+00	1223	COG0587	DNA polymerase III, alpha subunit	1139
648929297	263	53.75	3	255	1	252	2.0e-96	345	COG0052	Ribosomal protein S2	252
648929298	305	51.78	1	305	2	296	2.0e-90	325	COG0264	Translation elongation factor EF-Ts	296
648929299	239	55.51	3	237	1	236	1.0e-81	296	COG0528	Uridylate kinase	238
648929300	187	51.87	1	187	1	187	3.0e-64	238	COG0233	Ribosome recycling factor	187
648929301	255	55.84	20	250	15	245	7.0e-88	316	COG0020	Undecaprenyl pyrophosphate synthase	245
648929302	270	35.23	3	256	1	264	1.0e-28	120	COG0575	CDP-diglyceride synthetase	265
648929303	405	50.26	19	405	1	383	0.0e+00	466	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
648929304	378	42.06	11	373	1	371	7.0e-58	218	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
648929305	792	39.7	7	792	1	766	0.0e+00	634	COG4775	Outer membrane protein assembly factor BamA	766
648929306	346	45.4	28	341	18	326	1.0e-86	313	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
648929307	161	52.38	16	160	1	145	1.0e-45	175	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
648929308	265	52.51	1	259	3	260	3.0e-88	318	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
648929309	291	47.64	12	286	5	277	8.0e-70	257	COG3494	Uncharacterized conserved protein, DUF1009 family	279
648929310	406	41.34	8	390	2	377	2.0e-99	356	COG0763	Lipid A disaccharide synthetase	381
648929315	508	44.38	89	247	1	157	2.0e-28	120	COG3436	Transposase	157
648929317	808	27.92	417	806	40	404	1.0e-24	109	COG0840	Methyl-accepting chemotaxis protein	408
648929318	430	54.07	26	429	1	390	0.0e+00	501	COG0372	Citrate synthase	390
648929319	471	40.84	1	467	6	466	1.0e-129	457	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
648929323	708	22.48	6	470	6	438	5.0e-24	106	COG0658	Predicted membrane metal-binding protein	453
648929324	239	40.42	1	239	3	200	2.0e-53	202	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
648929326	746	38.98	485	738	1	253	2.0e-61	231	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
648929328	210	29.21	2	195	1	199	1.0e-22	99.9	COG0625	Glutathione S-transferase	211
648929329	318	22.81	46	263	7	231	1.0e-14	74.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648929330	262	27.52	5	149	4	148	1.0e-09	57.4	COG5501	Predicted secreted protein	148
648929331	293	21.69	40	282	26	260	9.0e-12	64.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
648929334	323	27.05	18	297	39	326	2.0e-26	112	COG3391	DNA-binding beta-propeller fold protein YncE	381
648929335	243	42.01	1	217	1	219	2.0e-59	222	COG1131	ABC-type multidrug transport system, ATPase component	293
648929336	264	25.84	40	247	64	269	3.0e-06	45.7	COG0842	ABC-type multidrug transport system, permease component	286
648929339	195	40.48	1	195	3	212	1.0e-49	189	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
648929340	253	29.37	3	253	6	256	2.0e-32	132	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
648929341	324	19.38	1	310	1	312	8.0e-11	61.4	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
648929346	236	41.29	10	210	2	201	4.0e-44	171	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
648929347	453	31.49	23	309	56	336	5.0e-37	149	COG0642	Signal transduction histidine kinase	336
648929348	402	33.78	29	389	21	379	5.0e-73	268	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
648929349	226	51.35	1	147	1	146	4.0e-36	144	COG3427	Carbon monoxide dehydrogenase subunit G	146
648929350	174	52.23	12	167	1	155	8.0e-54	203	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
648929351	787	38.91	6	776	6	727	0.0e+00	635	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
648929352	266	36.3	1	266	1	280	2.0e-54	206	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
648929353	582	53.26	10	576	4	568	0.0e+00	687	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
648929354	429	19.19	7	349	6	277	4.0e-12	66.5	COG1566	Multidrug resistance efflux pump	352
648929355	400	45.02	1	400	4	401	1.0e-104	373	COG0303	Molybdopterin biosynthesis enzyme	404
648929356	171	61.39	4	161	1	157	3.0e-58	217	COG0315	Molybdenum cofactor biosynthesis enzyme	157
648929357	270	57.75	5	262	1	254	3.0e-85	308	COG0134	Indole-3-glycerol phosphate synthase	254
648929358	337	52.07	1	337	1	338	4.0e-119	421	COG0547	Anthranilate phosphoribosyltransferase	338
648929361	256	48.99	10	256	3	248	8.0e-73	267	COG0149	Triosephosphate isomerase	251
648929362	124	50.65	1	76	1	77	2.0e-12	64.8	COG1314	Preprotein translocase subunit SecG	86
648929364	542	61.85	3	540	2	531	0.0e+00	855	COG0504	CTP synthase (UTP-ammonia lyase)	533
648929366	384	33.33	11	374	9	365	1.0e-32	134	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
648929367	1051	46.16	1	1026	1	1007	0.0e+00	940	COG0841	Multidrug efflux pump subunit AcrB	1009
648929368	370	41.25	1	370	1	377	5.0e-96	344	COG1454	Alcohol dehydrogenase, class IV	377
648929369	374	23.47	11	372	19	401	9.0e-43	167	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
648929373	321	49.69	1	320	1	318	1.0e-98	353	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
648929375	142	33.33	1	142	4	152	9.0e-14	69.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
648929376	245	50	5	223	11	220	4.0e-34	138	COG0785	Cytochrome c biogenesis protein CcdA	220
648929378	450	45.43	4	442	1	459	0.0e+00	518	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
648929379	608	52.71	1	608	1	597	0.0e+00	790	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
648929380	127	41.88	1	117	1	117	3.0e-25	107	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
648929381	253	47.12	19	226	2	207	5.0e-67	247	COG2928	Uncharacterized membrane protein	222
648929382	700	52.45	1	691	1	677	0.0e+00	825	COG1200	RecG-like helicase	677
648929383	101	40.7	9	94	4	88	1.0e-18	84.5	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
648929384	1162	46.38	8	1161	8	1139	0.0e+00	1349	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
648929385	114	26.26	4	102	13	108	8.0e-09	52.6	COG2919	Cell division protein FtsB	117
648929386	348	49.1	19	347	12	342	5.0e-118	417	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
648929387	459	54.97	137	457	3	323	0.0e+00	474	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
648929389	309	40.65	2	309	119	403	2.0e-72	266	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
648929390	482	47.33	6	471	5	453	0.0e+00	483	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
648929393	140	31.11	6	137	1	135	1.0e-22	98.8	COG0824	Acyl-CoA thioesterase FadM	137
648929394	328	60.66	17	321	2	306	0.0e+00	479	COG0320	Lipoate synthase	306
648929395	150	41.61	1	149	1	144	5.0e-43	166	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
648929399	168	51.33	17	166	10	157	9.0e-42	163	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
648929400	440	54.84	278	432	1	155	3.0e-59	223	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
648929401	354	44.48	22	343	3	321	4.0e-83	301	COG0042	tRNA-dihydrouridine synthase	323
648929402	383	49.3	20	375	11	363	6.0e-121	427	COG3852	Signal transduction histidine kinase, nitrogen specific	363
648929403	479	45.96	1	479	2	463	0.0e+00	522	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
648929404	746	45.61	24	729	8	706	0.0e+00	688	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
648929405	455	45.87	1	455	3	457	0.0e+00	507	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
648929406	458	30.17	1	231	1	225	1.0e-43	171	COG0569	Trk K+ transport system, NAD-binding component	225
648929407	287	33.21	3	278	2	276	1.0e-57	216	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
648929408	85	63.64	2	78	1	77	2.0e-28	116	COG1923	sRNA-binding regulator protein Hfq	77
648929409	463	46.98	54	450	13	405	5.0e-115	408	COG2262	50S ribosomal subunit-associated GTPase HflX	411
648929413	182	30.19	70	174	27	131	7.0e-07	47.1	COG1917	Cupin domain protein related to quercetin dioxygenase	131
648929414	383	32.94	128	380	6	258	2.0e-45	177	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
648929415	307	30.45	65	307	27	258	4.0e-40	158	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
648929416	156	21.58	10	131	4	141	1.0e-09	55.7	COG1247	L-amino acid N-acyltransferase YncA	169
648929417	278	49.02	23	277	3	248	6.0e-86	310	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
648929418	468	34.97	2	446	1	430	2.0e-115	409	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
648929419	418	25.17	11	416	1	409	8.0e-47	181	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648929420	441	46.86	4	440	3	444	0.0e+00	520	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
648929424	214	21.53	5	211	1	201	2.0e-12	65.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648929426	197	36.55	1	197	1	192	7.0e-32	130	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
648929427	266	32.34	5	264	4	261	3.0e-41	162	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
648929428	265	48.25	1	255	2	256	4.0e-82	297	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
648929431	229	44.13	1	212	1	207	4.0e-56	211	COG0125	Thymidylate kinase	208
648929432	389	36.72	9	389	12	389	2.0e-74	272	COG1686	D-alanyl-D-alanine carboxypeptidase	389
648929433	374	42.74	38	262	8	232	6.0e-49	188	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
648929436	431	24.49	147	373	45	266	8.0e-07	48.7	COG4974	Site-specific recombinase XerD	300
648929441	265	21.03	24	251	4	221	2.0e-09	56.9	COG2801	Transposase InsO and inactivated derivatives	232
648929443	196	50.55	28	116	11	101	6.0e-22	97.7	COG3561	Phage anti-repressor protein	110
648929450	434	29.55	20	432	4	442	1.0e-60	227	COG3182	Uncharacterized iron-regulated membrane protein	442
648929460	420	21.56	5	409	51	435	6.0e-20	92.2	COG0305	Replicative DNA helicase	435
648929470	256	33.33	1	179	1	181	2.0e-20	93.2	COG4422	Bacteriophage protein gp37	250
648929472	305	34.28	1	305	4	321	3.0e-61	228	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
648929473	382	33.33	1	380	6	368	1.0e-67	250	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
648929474	299	25.34	6	297	5	293	3.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
648929482	342	27.2	11	340	7	353	2.0e-46	179	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
648929483	323	44.2	5	321	3	314	1.0e-74	273	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
648929485	323	23.76	1	299	2	267	2.0e-24	107	COG0388	Predicted amidohydrolase	274
648929489	500	52.04	13	496	1	484	0.0e+00	576	COG1492	Cobyric acid synthase	486
648929490	155	25	24	150	4	155	1.0e-05	42.6	COG1247	L-amino acid N-acyltransferase YncA	169
648929491	211	57.14	16	211	4	198	3.0e-69	254	COG2109	ATP:corrinoid adenosyltransferase	198
648929492	1254	37.96	11	1245	9	1241	0.0e+00	1088	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
648929493	365	35.91	7	360	1	320	4.0e-66	245	COG0523	GTPase, G3E family	323
648929494	186	48.85	11	177	1	174	2.0e-54	205	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
648929497	397	43.14	1	397	4	396	2.0e-95	342	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
648929499	258	43.57	12	252	1	233	2.0e-72	265	COG3910	Predicted ATPase	233
648929500	339	22.9	61	336	9	296	1.0e-17	84.4	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
648929501	459	29.97	164	458	37	329	7.0e-36	145	COG0642	Signal transduction histidine kinase	336
648929502	220	39.65	1	219	1	226	7.0e-49	187	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648929503	327	34.48	10	327	5	318	5.0e-58	218	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
648929505	504	46.44	1	503	3	504	3.0e-127	449	COG3333	TctA family transporter	504
648929508	431	46.01	1	424	9	431	7.0e-121	427	COG2907	Predicted NAD/FAD-binding protein	447
648929509	281	39.38	17	273	4	260	2.0e-65	242	COG3496	Uncharacterized conserved protein, DUF1365 family	261
648929510	404	42.11	119	403	3	283	4.0e-87	315	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
648929511	271	34.86	15	232	9	219	9.0e-39	154	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
648929512	218	33.02	9	217	7	215	2.0e-27	115	COG3806	Anti-sigma factor ChrR, cupin superfamily	216
648929514	344	50.16	3	315	1	300	5.0e-101	361	COG0031	Cysteine synthase	300
648929515	504	35.81	77	504	1	438	3.0e-70	259	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
648929516	216	37.98	7	213	2	208	5.0e-28	117	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
648929517	240	46.25	3	238	1	234	2.0e-64	238	COG2872	Ser-tRNA(Ala) deacylase AlaX (editing enzyme)	241
648929518	161	27.46	1	142	2	133	9.0e-20	89.7	COG3791	Uncharacterized conserved protein	133
648929519	284	44.48	1	281	6	283	3.0e-87	314	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
648929520	158	34.31	20	155	1	137	1.0e-17	82.8	COG3187	Heat shock protein HslJ	142
648929522	267	62.76	27	265	3	240	2.0e-117	415	COG1126	ABC-type polar amino acid transport system, ATPase component	240
648929523	384	34.36	156	382	3	222	4.0e-45	175	COG0765	ABC-type amino acid transport system, permease component	222
648929524	392	58.49	10	392	15	397	0.0e+00	480	COG4597	ABC-type amino acid transport system, permease component	397
648929525	371	29.5	33	287	1	256	2.0e-29	123	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
648929527	428	38.52	49	426	9	395	4.0e-110	391	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
648929528	104	55.34	1	103	8	110	1.0e-26	111	COG3952	Uncharacterized N-terminal domain of lipid-A-disaccharide synthase	113
648929529	267	26.52	17	244	4	227	3.0e-20	92.1	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
648929530	309	21.05	51	250	9	215	3.0e-07	49.4	COG0671	Membrane-associated phospholipid phosphatase	232
648929531	587	24.32	38	509	5	477	8.0e-45	175	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
648929532	306	31.65	35	300	3	268	2.0e-28	120	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
648929533	189	25.9	15	179	42	207	5.0e-16	77.9	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
648929536	513	21.78	152	484	61	388	4.0e-14	73.1	COG1944	Ribosomal protein S12 methylthiotransferase accessory factor YcaO	398
648929539	649	21.27	6	253	16	280	2.0e-13	71.1	COG3629	DNA-binding transcriptional activator of the SARP family	280
648929542	280	29.04	16	268	4	271	2.0e-26	112	COG0338	Site-specific DNA-adenine methylase	274
648929555	523	22.81	124	521	37	439	4.0e-25	109	COG5184	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	476
648929566	286	38.93	135	264	1	131	4.0e-33	135	COG1943	REP element-mobilizing transposase RayT	136
648929567	414	26.25	2	377	1	345	3.0e-30	126	COG0675	Transposase	364
648929577	546	28.23	41	535	36	492	1.0e-50	194	COG5511	Bacteriophage capsid protein	492
648929579	697	25.08	11	652	1	590	1.0e-56	215	COG5525	Phage terminase, large subunit GpA	611
648929581	206	20.23	41	204	5	174	7.0e-08	50.7	COG0250	Transcription antitermination factor NusG	178
648929588	383	39.74	1	310	2	226	7.0e-59	221	COG4422	Bacteriophage protein gp37	250
648929589	86	52.5	1	80	5	84	3.0e-18	83.4	COG3750	Uncharacterized conserved protein, UPF0335 family	85
648929590	373	19.27	9	358	14	281	1.0e-22	100	COG0863	DNA modification methylase	302
648929607	142	37.14	4	141	5	143	1.0e-20	92.3	COG3793	Tellurite resistance protein	144
648929619	508	44.38	89	247	1	157	2.0e-28	120	COG3436	Transposase	157
648929625	258	39.69	1	253	3	257	1.0e-49	190	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648929627	207	33.33	1	179	1	181	4.0e-21	94.8	COG4422	Bacteriophage protein gp37	250
648929631	265	21.03	24	251	4	221	8.0e-10	57.7	COG2801	Transposase InsO and inactivated derivatives	232
648929635	207	33.33	1	179	1	181	4.0e-21	94.8	COG4422	Bacteriophage protein gp37	250
648929642	388	27.06	1	379	1	381	1.0e-33	137	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648929644	230	22.48	2	227	21	278	4.0e-19	88.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648929645	252	54	1	250	1	242	2.0e-89	322	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
648929646	437	40.82	22	436	1	447	5.0e-117	414	COG0527	Aspartokinase	447
648929647	755	55.84	12	750	5	745	0.0e+00	898	COG3605	Signal transduction protein containing GAF and PtsI domains	756
648929648	359	65.28	1	356	3	361	0.0e+00	507	COG0216	Protein chain release factor A	363
648929649	280	41.99	1	280	1	277	2.0e-58	219	COG2890	Methylase of polypeptide chain release factors	280
648929652	865	57.13	5	856	1	782	0.0e+00	994	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
648929653	635	35.27	404	603	66	270	5.0e-34	139	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
648929661	277	33.65	45	248	28	235	2.0e-23	103	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
648929663	338	23.49	4	334	8	297	1.0e-38	153	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
648929664	260	41.22	1	258	2	251	6.0e-45	174	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648929667	420	47.38	9	409	1	356	1.0e-130	460	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
648929668	299	42.16	12	293	1	281	3.0e-68	252	COG2240	Pyridoxal/pyridoxine/pyridoxamine kinase	281
648929669	249	44.03	14	249	7	245	2.0e-52	199	COG4923	Predicted nuclease (RNAse H fold)	245
648929670	307	47.1	1	305	3	300	2.0e-89	322	COG4974	Site-specific recombinase XerD	300
648929672	204	45.29	28	197	1	170	6.0e-54	203	COG0703	Shikimate kinase	172
648929673	382	52.47	15	378	1	356	2.0e-120	426	COG0337	3-dehydroquinate synthetase	360
648929674	445	51.2	6	421	2	416	0.0e+00	526	COG4536	Mg2+ and Co2+ transporter CorB, contains DUF21, CBS pair, and CorC-HlyC domains	423
648929675	98	49.44	1	88	1	86	2.0e-21	93.5	COG0271	Stress-induced morphogen (activity unknown)	90
648929678	336	16.77	28	334	1	303	1.0e-41	164	COG0714	MoxR-like ATPase	329
648929679	637	64.59	13	619	13	620	0.0e+00	738	COG4547	Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib...	620
648929680	348	39.76	9	344	4	338	1.0e-62	233	COG4246	Uncharacterized protein	340
648929681	214	29.33	8	213	1	208	2.0e-20	92.2	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
648929682	219	29.52	12	211	26	223	6.0e-21	94.6	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
648929683	129	52.05	32	104	1	73	1.0e-19	88.4	COG0227	Ribosomal protein L28	77
648929686	318	54.92	1	315	1	314	5.0e-123	433	COG0825	Acetyl-CoA carboxylase alpha subunit	317
648929688	408	41.76	26	298	7	272	1.0e-75	277	COG3034	Murein L,D-transpeptidase YafK	298
648929690	483	35.86	23	483	2	473	4.0e-87	315	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
648929692	350	34.21	1	150	8	157	2.0e-19	90.5	COG2030	Acyl dehydratase	159
648929693	446	32.42	41	435	21	413	9.0e-72	264	COG0112	Glycine/serine hydroxymethyltransferase	413
648929696	663	42.63	5	499	65	548	0.0e+00	492	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
648929698	431	28.01	39	412	1	326	1.0e-51	197	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
648929699	174	21.08	8	172	42	207	4.0e-14	71.4	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
648929701	243	43.66	29	239	57	266	1.0e-54	206	COG3757	Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family	269
648929702	269	38.38	5	267	1	259	7.0e-78	284	COG0708	Exonuclease III	261
648929703	324	41.77	1	324	1	326	3.0e-75	275	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
648929705	188	33.52	8	186	2	182	7.0e-26	110	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
648929707	406	52.02	31	399	1	349	3.0e-129	455	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
648929708	713	24.75	306	706	24	406	5.0e-34	139	COG0840	Methyl-accepting chemotaxis protein	408
648929709	727	26.46	12	726	3	725	2.0e-89	324	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
648929710	153	56.49	1	152	2	155	3.0e-55	207	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
648929711	196	19.58	4	192	10	191	4.0e-11	61.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648929712	406	58.5	7	404	5	400	0.0e+00	605	COG0137	Argininosuccinate synthase	403
648929714	154	36.42	4	151	11	157	7.0e-24	103	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
648929716	175	53.25	11	164	1	154	2.0e-49	188	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
648929717	304	46.59	37	295	2	265	7.0e-73	267	COG0294	Dihydropteroate synthase	274
648929718	402	20.75	1	395	3	388	6.0e-19	88.7	COG2814	Predicted arabinose efflux permease, MFS family	394
648929722	608	61.86	1	602	3	603	0.0e+00	928	COG1217	Predicted membrane GTPase involved in stress response	603
648929729	346	44.59	18	345	3	370	1.0e-64	240	COG3329	Uncharacterized conserved protein	372
648929731	213	33.01	1	205	7	206	2.0e-40	159	COG0288	Carbonic anhydrase	207
648929732	163	32.52	1	163	2	164	2.0e-28	118	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
648929733	271	37.84	13	265	1	258	8.0e-16	77.7	COG0730	Uncharacterized membrane protein YfcA	258
648929736	236	28.7	20	232	3	217	3.0e-31	128	COG0819	Thiaminase	218
648929737	368	53.41	26	356	1	334	1.0e-119	423	COG0136	Aspartate-semialdehyde dehydrogenase	334
648929739	247	32.49	17	247	8	237	1.0e-37	150	COG3473	Maleate cis-trans isomerase	238
648929740	378	28.68	2	378	1	383	5.0e-52	198	COG0006	Xaa-Pro aminopeptidase	384
648929741	360	27.11	28	356	13	313	5.0e-39	155	COG1171	Threonine dehydratase	347
648929746	508	44.38	89	247	1	157	2.0e-28	120	COG3436	Transposase	157
648929750	534	21.94	132	516	40	406	2.0e-25	110	COG0840	Methyl-accepting chemotaxis protein	408
648929753	409	50	40	407	1	348	7.0e-114	404	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
648929757	390	50.63	1	389	2	392	2.0e-130	458	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
648929758	222	49.53	5	216	8	218	5.0e-61	227	COG3897	Predicted nicotinamide N-methyase	218
648929759	141	51.28	1	140	2	155	3.0e-49	187	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
648929760	96	42.39	1	90	1	92	7.0e-22	95.4	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
648929761	331	45.73	5	331	2	329	3.0e-102	365	COG0240	Glycerol-3-phosphate dehydrogenase	329
648929763	380	51.02	27	365	3	336	1.0e-123	436	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
648929764	307	53.64	6	306	4	303	1.0e-104	373	COG0181	Porphobilinogen deaminase	307
648929765	235	26.94	1	232	2	242	7.0e-19	87.4	COG1587	Uroporphyrinogen-III synthase	248
648929767	656	43.59	1	521	1	502	7.0e-100	358	COG3898	Uncharacterized membrane-anchored protein	531
648929771	280	38.11	2	275	7	313	4.0e-66	244	COG0627	S-formylglutathione hydrolase FrmB	316
648929772	370	64.86	1	370	1	366	0.0e+00	537	COG1062	Zn-dependent alcohol dehydrogenase	366
648929774	263	36.92	1	259	2	257	2.0e-45	176	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648929776	546	34.16	18	542	1	522	0.0e+00	481	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
648929777	664	54.93	1	658	1	645	0.0e+00	816	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
648929778	140	35.71	1	134	1	140	1.0e-25	108	COG4405	Uncharacterized protein YhfF	140
648929779	535	44.22	12	535	1	526	0.0e+00	624	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
648929780	227	25.39	19	210	1	191	7.0e-12	64.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648929781	302	60.69	15	272	9	270	3.0e-100	358	COG2326	Polyphosphate kinase 2, PPK2 family	270
648929782	361	33.53	28	359	1	340	6.0e-51	195	COG0673	Predicted dehydrogenase	342
648929783	154	65.58	1	154	21	174	2.0e-58	218	COG0290	Translation initiation factor IF-3	176
648929786	131	39.22	25	125	12	113	7.0e-21	92.7	COG3339	Uncharacterized membrane protein YkvA, DUF1232 family	116
648929787	562	42.57	172	560	4	391	6.0e-76	278	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648929788	284	31.39	13	282	19	292	8.0e-36	144	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
648929792	670	21.66	271	667	32	403	3.0e-23	103	COG0840	Methyl-accepting chemotaxis protein	408
648929794	468	39.02	10	457	2	444	2.0e-83	303	COG2233	Xanthine/uracil permease	451
648929795	265	27.27	1	263	1	280	1.0e-19	90.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648929804	508	44.38	89	247	1	157	2.0e-28	120	COG3436	Transposase	157
648929808	388	28.8	168	358	1	175	1.0e-20	94.1	COG2114	Adenylate cyclase, class 3	227
648929810	146	21.31	20	138	15	136	6.0e-06	43.7	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
648929811	340	31.18	21	278	2	257	3.0e-24	105	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
648929812	915	54.15	4	905	1	820	0.0e+00	1060	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
648929815	412	50.49	5	412	1	404	0.0e+00	493	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
648929816	132	32.26	1	123	6	127	3.0e-10	57.3	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
648929820	209	36.67	25	204	5	176	1.0e-31	129	COG1040	Predicted amidophosphoribosyltransferases	225
648929824	85	53.16	3	80	2	80	3.0e-21	93.1	COG0695	Glutaredoxin	80
648929825	282	35	4	279	3	272	2.0e-50	192	COG0388	Predicted amidohydrolase	274
648929826	181	41.99	1	181	1	142	4.0e-38	150	COG5319	Uncharacterized protein	142
648929828	329	34.86	1	326	2	323	1.0e-58	220	COG4644	Transposase and inactivated derivatives, TnpA family	323
648929830	338	31.17	33	336	2	314	7.0e-41	161	COG0451	Nucleoside-diphosphate-sugar epimerase	314
648929831	364	72.17	6	349	3	345	0.0e+00	589	COG1089	GDP-D-mannose dehydratase	345
648929834	526	26.77	22	289	7	257	2.0e-17	84.3	COG4584	Transposase	278
648929837	263	38.33	13	248	13	251	2.0e-41	162	COG1484	DNA replication protein DnaC	254
648929840	330	14.63	3	328	11	322	1.0e-06	47.7	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
648929842	485	20.81	247	466	2	221	6.0e-14	72.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
648929855	999	19.44	138	647	1	468	7.0e-12	67	COG0286	Type I restriction-modification system, DNA methylase subunit	489
648929856	205	29.63	53	187	10	134	6.0e-13	67.7	COG3415	Transposase	138
648929859	508	44.38	89	247	1	157	2.0e-28	120	COG3436	Transposase	157
648929868	549	39.77	139	309	16	176	1.0e-26	115	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
648929869	817	64.11	16	574	1	556	0.0e+00	901	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
648929870	379	36.68	8	373	2	360	3.0e-82	299	COG1195	Recombinational DNA repair ATPase RecF	363
648929871	372	44.35	1	372	1	364	3.0e-92	332	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
648929872	494	42.12	12	490	1	408	2.0e-110	393	COG0593	Chromosomal replication initiation ATPase DnaA	408
648929874	88	53.41	1	88	1	88	5.0e-11	59.1	COG0268	Ribosomal protein S20	88
648929876	257	46.12	1	254	2	257	6.0e-62	230	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648929877	297	47.81	1	297	1	273	1.0e-94	339	COG0266	Formamidopyrimidine-DNA glycosylase	273
648929878	266	50.82	24	266	1	238	2.0e-77	282	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
648929879	527	42	8	523	7	514	4.0e-128	452	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
648929880	206	39.59	2	198	8	194	1.0e-38	153	COG3145	Alkylated DNA repair dioxygenase AlkB	194
648929881	666	65.07	25	627	1	579	0.0e+00	710	COG0443	Molecular chaperone DnaK (HSP70)	579
648929883	374	61.33	1	373	1	371	0.0e+00	497	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
648929884	218	47.8	28	208	11	191	8.0e-44	170	COG3963	Phospholipid N-methyltransferase	194
648929885	196	35.14	4	188	1	169	8.0e-27	113	COG0431	NAD(P)H-dependent FMN reductase	184
648929886	186	66.1	10	185	2	178	3.0e-72	264	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
648929887	434	64.49	1	434	1	444	0.0e+00	659	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
648929888	164	26.14	9	154	1	153	1.0e-05	43	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
648929889	186	47.62	105	186	1	84	2.0e-23	102	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
648929890	225	33.03	1	216	1	218	7.0e-36	144	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
648929891	162	31.25	14	162	17	174	1.0e-16	79.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
648929892	150	51.2	7	131	12	135	1.0e-33	135	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
648929893	256	22.03	1	229	11	236	8.0e-20	91.1	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
648929896	374	44.99	12	357	2	347	5.0e-103	368	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
648929897	171	43.42	10	161	1	150	5.0e-36	143	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
648929899	541	35.29	18	541	10	518	1.0e-98	353	COG0815	Apolipoprotein N-acyltransferase	518
648929900	135	20.83	13	131	1	120	3.0e-08	50.8	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
648929901	390	59.64	3	390	2	387	0.0e+00	567	COG0192	S-adenosylmethionine synthetase	388
648929902	232	33.78	9	228	5	225	9.0e-52	196	COG0220	tRNA G46 methylase TrmB	227
648929903	200	36.88	9	167	1	153	1.0e-35	143	COG0779	Ribosome maturation factor RimP	153
648929904	559	58.67	161	355	1	190	4.0e-51	196	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
648929905	217	35.16	2	92	1	87	7.0e-14	70.8	COG2740	Predicted RNA-binding protein YlxR, DUF448 family	95
648929906	915	59.14	411	915	1	507	0.0e+00	635	COG0532	Translation initiation factor IF-2, a GTPase	509
648929907	136	34.45	12	128	3	118	1.0e-21	95.3	COG0858	Ribosome-binding factor A	118
648929908	314	34.32	12	314	12	271	7.0e-57	214	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
648929910	89	64.04	1	89	1	89	8.0e-28	115	COG0184	Ribosomal protein S15P/S13E	89
648929912	710	63.79	1	695	1	692	0.0e+00	1009	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
648929914	270	52.45	4	268	3	266	9.0e-88	316	COG0289	Dihydrodipicolinate reductase	266
648929915	206	49.78	3	200	2	224	4.0e-74	270	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
648929916	333	29.97	7	318	1	295	2.0e-38	153	COG0524	Sugar or nucleoside kinase, ribokinase family	311
648929917	296	44.4	6	279	4	279	8.0e-84	303	COG0077	Prephenate dehydratase	279
648929918	242	47.77	1	241	1	242	2.0e-76	278	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
648929919	183	45.71	38	177	2	134	7.0e-33	133	COG3474	Cytochrome c2	135
648929920	483	45	308	466	15	173	6.0e-37	149	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
648929922	607	28.97	2	601	10	562	4.0e-80	292	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
648929923	619	26.44	1	613	1	562	4.0e-71	263	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
648929924	372	71.43	1	371	1	364	0.0e+00	582	COG4174	ABC-type microcin C transport system, permease component YejB	364
648929925	382	66.21	18	380	1	340	0.0e+00	517	COG4239	ABC-type microcin C transport system, permease component YejE	341
648929926	543	67.79	1	534	1	534	0.0e+00	857	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
648929930	399	40.85	12	338	26	340	2.0e-74	272	COG2951	Membrane-bound lytic murein transglycosylase B	343
648929932	149	21.52	1	148	2	158	4.0e-10	57.5	COG0406	Broad specificity phosphatase PhoE	208
648929933	314	39.46	20	311	1	279	1.0e-67	250	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
648929934	137	23.7	1	129	2	135	6.0e-15	73.1	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
648929935	610	40.96	20	510	2	491	1.0e-118	420	COG2812	DNA polymerase III, gamma/tau subunits	515
648929936	106	50.52	1	97	5	101	1.0e-21	94.9	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
648929937	202	52.53	5	202	1	198	2.0e-74	272	COG0353	Recombinational DNA repair protein RecR	198
648929939	222	23.63	2	216	5	241	2.0e-28	118	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
648929940	301	50.33	2	300	7	309	1.0e-102	366	COG2066	Glutaminase	309
648929942	235	37.93	1	225	5	236	1.0e-35	143	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
648929943	132	44.53	10	132	3	130	6.0e-16	76.5	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
648929944	127	29.06	8	124	1	117	3.0e-19	87.5	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
648929945	608	52.99	9	586	4	562	0.0e+00	640	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
648929947	260	54.74	29	260	4	232	3.0e-88	317	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
648929948	481	35.45	27	479	2	435	8.0e-108	384	COG4452	Inner membrane protein involved in colicin E2 resistance	443
648929950	213	44.74	18	165	1	152	2.0e-46	179	COG0225	Peptide methionine sulfoxide reductase MsrA	174
648929951	183	26.78	11	183	26	199	3.0e-13	68.5	COG3637	Opacity protein and related surface antigens	199
648929952	627	50.75	28	626	6	590	0.0e+00	708	COG0514	Superfamily II DNA helicase RecQ	590
648929953	324	23.94	41	323	2	278	6.0e-43	168	COG3176	Putative hemolysin	292
648929954	125	39.52	1	123	1	124	5.0e-18	83	COG3686	Uncharacterized conserved protein, MAPEG superfamily	125
648929960	380	53.12	11	379	13	366	8.0e-122	430	COG1485	Predicted ATPase	367
648929961	320	46.35	4	317	1	312	4.0e-105	374	COG0039	Malate/lactate dehydrogenase	313
648929962	399	57.64	1	397	1	386	0.0e+00	504	COG0045	Succinyl-CoA synthetase, beta subunit	387
648929963	302	63.58	1	302	1	291	4.0e-114	404	COG0074	Succinyl-CoA synthetase, alpha subunit	293
648929964	994	55.26	7	993	1	905	0.0e+00	1342	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
648929965	504	48.16	106	503	2	404	1.0e-105	377	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
648929966	204	39.8	5	204	9	208	4.0e-26	111	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
648929967	467	53.71	1	457	2	454	0.0e+00	527	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
648929969	139	41.51	3	107	1	106	7.0e-20	89.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
648929971	318	29.32	11	315	4	284	2.0e-44	173	COG1408	Predicted phosphohydrolase, MPP superfamily	284
648929975	177	24.69	7	160	1	162	2.0e-13	68.8	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648929977	320	33.88	15	317	3	299	2.0e-58	219	COG4974	Site-specific recombinase XerD	300
648929978	217	52.81	1	217	8	238	4.0e-67	247	COG0176	Transaldolase	239
648929979	732	46.3	13	731	3	730	0.0e+00	782	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
648929980	121	48.74	1	119	1	117	2.0e-31	127	COG5507	Uncharacterized  conserved protein YbaA, DUF1428 family	117
648929981	186	44.38	6	183	2	178	3.0e-33	134	COG0712	FoF1-type ATP synthase, delta subunit	178
648929982	509	68.96	1	509	1	501	0.0e+00	830	COG0056	FoF1-type ATP synthase, alpha subunit	504
648929983	294	47.59	5	294	1	286	5.0e-91	327	COG0224	FoF1-type ATP synthase, gamma subunit	287
648929984	474	77.47	4	472	1	468	0.0e+00	809	COG0055	FoF1-type ATP synthase, beta subunit	468
648929985	135	35.54	4	123	3	123	3.0e-24	103	COG0355	FoF1-type ATP synthase, epsilon subunit	135
648929987	539	39.2	342	539	3	199	2.0e-40	160	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
648929990	519	61.72	2	512	16	526	0.0e+00	783	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
648929992	232	42.24	2	231	1	227	9.0e-55	206	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648929993	600	29.82	270	599	21	330	2.0e-37	150	COG0642	Signal transduction histidine kinase	336
648929995	134	38.52	1	133	1	134	4.0e-28	117	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
648929996	93	50	6	91	2	87	4.0e-21	92.9	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
648929997	462	58.42	1	454	2	420	0.0e+00	641	COG0499	S-adenosylhomocysteine hydrolase	420
648929998	812	38	562	806	93	334	2.0e-40	161	COG0642	Signal transduction histidine kinase	336
648929999	521	40.94	175	514	2	343	1.0e-82	301	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
648930001	1058	41.75	9	770	3	697	1.0e-128	455	COG3893	Inactivated superfamily I helicase	697
648930002	1174	28	6	1156	1	1139	0.0e+00	578	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
648930004	209	46.77	1	186	15	193	5.0e-41	161	COG0576	Molecular chaperone GrpE (heat shock protein)	193
648930005	203	46.23	1	197	4	202	1.0e-41	163	COG2860	Uncharacterized membrane protein YeiH	209
648930007	99	52.75	1	91	2	91	9.0e-28	115	COG0776	Bacterial nucleoid DNA-binding protein	94
648930008	335	28.94	6	302	9	317	2.0e-49	189	COG0616	Periplasmic serine protease, ClpP class	317
648930009	142	43.36	1	142	1	141	7.0e-33	133	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
648930010	564	54.71	8	558	2	541	0.0e+00	577	COG0539	Ribosomal protein S1	541
648930011	208	45.37	1	205	5	220	4.0e-61	227	COG0283	Cytidylate kinase	222
648930012	451	43.38	14	443	9	428	1.0e-106	380	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
648930013	130	50.38	1	129	1	128	1.0e-10	58.5	COG4530	Uncharacterized protein	129
648930016	143	46.32	7	141	21	155	2.0e-20	91.9	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
648930017	436	21.97	1	430	5	433	9.0e-41	161	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648930018	293	38.49	1	289	1	290	4.0e-49	188	COG1175	ABC-type sugar transport system, permease component	295
648930019	280	35.53	9	278	15	278	4.0e-47	181	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648930020	357	53.43	1	350	1	338	4.0e-129	454	COG3839	ABC-type sugar transport system, ATPase component	338
648930023	384	45.51	104	259	1	155	2.0e-38	154	COG4335	3-methyladenine DNA glycosylase AlkC	167
648930027	143	32.77	26	142	2	118	2.0e-21	94.9	COG2315	Predicted DNA-binding protein with ?double-wing? structural motif, MmcQ/YjbR family	118
648930029	283	21.07	5	280	1	296	5.0e-19	88.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
648930031	140	30.83	11	137	21	146	3.0e-18	84.3	COG0071	Molecular chaperone IbpA, HSP20 family	146
648930032	94	42.68	13	94	4	85	9.0e-16	75	COG5568	Uncharacterized protein	85
648930033	416	28.75	12	399	23	393	1.0e-36	147	COG4645	Uncharacterized protein	410
648930037	188	29.76	26	188	7	157	2.0e-23	102	COG1225	Peroxiredoxin	157
648930039	216	27.65	4	216	1	210	5.0e-29	121	COG0625	Glutathione S-transferase	211
648930043	284	23.5	36	255	45	274	7.0e-20	91.6	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
648930044	428	45.68	10	413	6	396	6.0e-122	431	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
648930045	537	29.24	1	530	1	532	4.0e-98	352	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
648930046	294	56.38	1	279	1	282	2.0e-97	348	COG0414	Panthothenate synthetase	285
648930047	269	53.79	8	269	1	264	2.0e-92	332	COG0413	Ketopantoate hydroxymethyltransferase	268
648930049	374	19.89	23	374	4	332	9.0e-17	81.6	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648930051	279	33.07	8	260	18	268	9.0e-35	140	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
648930059	351	54.07	1	344	1	338	4.0e-120	424	COG3839	ABC-type sugar transport system, ATPase component	338
648930060	410	21.14	61	407	72	433	4.0e-17	82.8	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648930061	341	29.26	102	326	54	281	1.0e-26	114	COG1175	ABC-type sugar transport system, permease component	295
648930062	293	28.97	6	292	4	281	1.0e-37	150	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648930063	182	27.84	56	152	36	131	5.0e-07	47.6	COG5485	Predicted ester cyclase	131
648930064	436	39.81	4	425	11	425	9.0e-122	430	COG0141	Histidinol dehydrogenase	425
648930066	255	40.78	10	253	1	251	2.0e-43	169	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648930067	343	38.44	6	335	1	332	4.0e-78	285	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
648930070	377	20.74	1	373	2	327	3.0e-29	122	COG0620	Methionine synthase II (cobalamin-independent)	330
648930071	231	24.62	1	229	21	280	2.0e-17	82.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648930072	231	23.44	1	207	6	191	2.0e-10	59.9	COG0684	Regulator of RNase E activity RraA	210
648930078	325	18.33	10	317	1	304	1.0e-10	61.1	COG0582	Integrase	309
648930084	612	27.84	5	602	112	751	2.0e-121	429	COG4993	Glucose dehydrogenase	773
648930085	194	44.32	1	181	1	184	2.0e-43	168	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648930086	525	26.25	271	518	78	335	1.0e-21	98.3	COG0642	Signal transduction histidine kinase	336
648930089	280	26.96	6	280	1	293	9.0e-29	120	COG0583	DNA-binding transcriptional regulator, LysR family	297
648930091	259	24.06	20	257	19	282	6.0e-17	81.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648930092	307	43.5	1	171	1	176	1.0e-33	137	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
648930093	344	28.31	24	344	17	329	9.0e-42	164	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
648930094	492	41.96	7	483	1	472	1.0e-127	450	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648930097	231	61.76	24	125	1	102	6.0e-35	141	COG0261	Ribosomal protein L21	103
648930098	89	60.92	1	87	1	87	2.0e-31	126	COG0211	Ribosomal protein L27	87
648930099	201	26.4	25	195	9	186	4.0e-18	84.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648930100	189	27.27	4	186	3	186	3.0e-17	81.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648930101	183	25	4	181	3	186	6.0e-21	93.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648930102	348	57.59	1	344	1	349	0.0e+00	478	COG0536	GTPase involved in cell partioning and DNA repair	369
648930103	373	53.8	1	364	3	368	2.0e-120	425	COG0263	Glutamate 5-kinase	369
648930104	426	57	14	426	5	417	0.0e+00	547	COG0014	Gamma-glutamyl phosphate reductase	417
648930105	215	32.8	23	208	2	170	2.0e-34	139	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
648930106	127	54.46	16	116	5	105	3.0e-34	137	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
648930107	160	37.74	1	159	1	155	4.0e-41	160	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
648930108	480	31.97	85	470	44	418	8.0e-70	258	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
648930109	445	44.31	4	397	1	399	8.0e-105	374	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
648930110	385	40.49	135	381	1	242	6.0e-55	208	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
648930111	176	21.09	25	170	17	149	8.0e-10	56.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
648930112	254	42.75	3	250	1	251	4.0e-42	165	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648930113	401	31.17	1	397	1	393	4.0e-61	228	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648930114	300	31.85	8	296	2	289	1.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
648930116	537	44.44	156	536	23	417	2.0e-119	423	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
648930117	924	38.29	5	922	6	944	0.0e+00	811	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
648930119	384	47.09	13	355	2	337	2.0e-103	369	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
648930120	230	33.02	2	211	1	201	2.0e-26	112	COG0625	Glutathione S-transferase	211
648930121	268	47.23	1	267	1	270	1.0e-70	259	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
648930122	351	28.44	16	348	4	310	1.0e-34	140	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
648930124	324	32.86	8	287	1	271	2.0e-31	130	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
648930126	554	22.96	265	504	21	254	5.0e-13	69.9	COG4974	Site-specific recombinase XerD	300
648930131	263	38.33	13	248	13	251	1.0e-41	163	COG1484	DNA replication protein DnaC	254
648930134	670	26.77	22	289	7	257	3.0e-17	84.3	COG4584	Transposase	278
648930139	265	21.03	24	251	4	221	3.0e-09	56.1	COG2801	Transposase InsO and inactivated derivatives	232
648930141	927	21.38	344	901	127	668	7.0e-55	209	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
648930146	508	44.38	89	247	1	157	2.0e-28	120	COG3436	Transposase	157
648930152	360	29.71	6	338	16	346	7.0e-44	171	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
648930154	278	32.76	43	273	13	239	3.0e-39	155	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
648930155	312	17.83	1	312	4	268	2.0e-13	69.7	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
648930156	409	29.41	19	398	3	377	6.0e-49	188	COG0006	Xaa-Pro aminopeptidase	384
648930157	284	37.92	13	280	6	267	1.0e-54	206	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
648930158	421	44.05	195	421	62	286	3.0e-60	225	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
648930159	366	21.41	6	363	11	362	2.0e-29	123	COG0687	Spermidine/putrescine-binding periplasmic protein	363
648930160	364	47.06	7	362	4	352	1.0e-113	403	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
648930162	152	29.08	10	150	7	146	5.0e-15	73.9	COG3909	Cytochrome c556	147
648930164	223	28.5	27	217	24	215	3.0e-24	105	COG5375	Uncharacterized protein	216
648930165	183	36.25	18	177	9	162	1.0e-21	96.5	COG1934	Lipopolysaccharide export system protein LptA	173
648930166	263	69.29	25	263	3	243	6.0e-111	393	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
648930167	508	41.35	3	504	1	444	0.0e+00	474	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
648930169	195	36.61	1	110	1	110	4.0e-20	91.4	COG1544	Ribosome-associated translation inhibitor RaiA	110
648930170	155	45.95	2	147	1	148	8.0e-31	126	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
648930171	608	34.8	7	581	50	634	8.0e-116	411	COG2943	Membrane glycosyltransferase	736
648930174	134	36.84	1	95	2	95	9.0e-09	52.6	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
648930178	394	20.16	11	378	15	380	8.0e-24	104	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648930179	303	13.8	17	303	108	417	7.0e-23	101	COG0172	Seryl-tRNA synthetase	429
648930181	827	17.8	10	811	15	802	4.0e-67	249	COG3250	Beta-galactosidase/beta-glucuronidase	808
648930183	506	18.72	1	463	5	468	4.0e-18	86.3	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
648930184	307	29.58	4	243	3	240	2.0e-22	100	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
648930185	371	16.3	81	346	27	249	3.0e-07	50	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
648930186	346	18.71	59	343	75	377	3.0e-06	46.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648930187	361	23.77	38	342	47	391	1.0e-23	104	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
648930189	298	41.42	55	291	15	253	3.0e-57	215	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
648930190	254	37.65	5	241	2	245	3.0e-49	188	COG2099	Precorrin-6x reductase	257
648930191	378	43.17	15	375	2	362	1.0e-94	339	COG1903	Cobalamin biosynthesis protein CbiD	367
648930192	289	47.98	17	264	1	244	2.0e-75	276	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
648930193	435	46.9	7	432	1	435	0.0e+00	465	COG1797	Cobyrinic acid a,c-diamide synthase	451
648930195	256	55.12	1	253	3	254	9.0e-96	343	COG2875	Precorrin-4 methylase	254
648930196	614	47.89	344	603	2	248	3.0e-81	296	COG1010	Precorrin-3B methylase	249
648930197	241	44.69	3	226	2	227	3.0e-60	225	COG2243	Precorrin-2 methylase	234
648930198	400	47.59	217	400	1	187	7.0e-53	201	COG2242	Precorrin-6B methylase 2	187
648930200	222	46.19	13	221	3	210	4.0e-55	207	COG2082	Precorrin isomerase	210
648930201	329	31.1	3	255	1	243	2.0e-36	146	COG2138	Sirohydrochlorin ferrochelatase	245
648930207	432	36.18	1	430	24	442	4.0e-72	265	COG3182	Uncharacterized iron-regulated membrane protein	442
648930208	172	30	1	169	2	171	7.0e-27	113	COG2716	Glycine cleavage system regulatory protein	176
648930211	302	32.24	1	299	1	297	4.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
648930212	339	49.85	2	339	1	337	1.0e-111	396	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
648930213	769	25.27	252	622	5	356	3.0e-34	140	COG3852	Signal transduction histidine kinase, nitrogen specific	363
648930216	413	14.53	14	402	24	424	2.0e-06	47.3	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648930220	237	31.91	1	235	3	236	3.0e-46	178	COG2188	DNA-binding transcriptional regulator, GntR family	236
648930221	150	56.67	6	149	2	151	9.0e-43	165	COG3624	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG	151
648930222	203	40.8	9	202	8	196	2.0e-31	129	COG3625	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH	196
648930223	360	66.57	1	360	1	361	0.0e+00	530	COG3626	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI	367
648930224	292	72.86	4	283	10	289	0.0e+00	484	COG3627	Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase	291
648930225	265	74.61	15	265	3	258	8.0e-116	410	COG4107	ABC-type phosphonate transport system, ATPase component	258
648930226	223	61.23	1	223	4	230	1.0e-85	309	COG4778	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL	235
648930231	211	44.59	40	196	1	154	1.0e-53	203	COG0225	Peptide methionine sulfoxide reductase MsrA	174
648930234	604	32.32	23	395	73	462	1.0e-80	294	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
648930235	216	35.83	27	212	3	184	9.0e-46	176	COG3575	Uncharacterized protein	184
648930237	805	40.24	144	804	1	650	0.0e+00	591	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
648930239	360	51.59	1	343	3	335	4.0e-123	435	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
648930241	315	24.91	7	291	1	292	2.0e-28	120	COG0583	DNA-binding transcriptional regulator, LysR family	297
648930243	601	68.6	1	601	1	602	0.0e+00	1062	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
648930244	377	48.56	100	376	22	279	7.0e-83	301	COG3770	Murein endopeptidase	284
648930245	361	26.46	8	360	11	328	6.0e-30	125	COG3621	Patatin-like phospholipase/acyl hydrolase	394
648930247	348	40.79	1	347	3	345	6.0e-80	291	COG1363	Putative aminopeptidase FrvX	355
648930248	217	35.78	12	214	1	204	2.0e-40	159	COG1186	Protein chain release factor B	239
648930249	395	26	23	371	17	431	1.0e-53	204	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
648930251	121	33.33	11	114	3	113	1.0e-15	75.4	COG1733	DNA-binding transcriptional regulator, HxlR family	120
648930253	69	70.31	1	64	1	63	1.0e-21	94.8	COG1278	Cold shock protein, CspA family	67
648930254	352	22.61	13	344	28	367	4.0e-33	135	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
648930256	221	31.86	14	217	12	206	4.0e-35	141	COG0400	Predicted esterase	207
648930259	291	20.71	4	283	2	305	6.0e-20	91.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
648930260	279	35.07	16	279	1	260	4.0e-57	214	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
648930261	326	24.66	45	323	105	392	1.0e-42	167	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
648930262	252	31.78	9	250	4	250	2.0e-39	156	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648930264	161	56.69	1	157	1	157	1.0e-49	189	COG2193	Bacterioferritin (cytochrome b1)	157
648930265	214	52.17	9	214	3	207	6.0e-59	220	COG4136	ABC-type uncharacterized transport system YnjBCD, ATPase component	213
648930266	500	33.41	30	463	9	435	9.0e-71	261	COG4135	ABC-type uncharacterized transport system YnjBCD, permease component	551
648930267	407	46.6	10	405	8	381	1.0e-94	340	COG4134	ABC-type uncharacterized transport system YnjBCD, periplasmic component	384
648930268	170	43.23	16	170	1	154	1.0e-32	132	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648930269	1106	53.76	509	1105	9	593	0.0e+00	721	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
648930271	824	42.87	11	820	49	843	0.0e+00	717	COG1643	HrpA-like RNA helicase	845
648930272	352	42.32	11	328	2	320	6.0e-81	294	COG0837	Glucokinase	320
648930273	141	54.01	1	137	1	135	6.0e-46	176	COG1803	Methylglyoxal synthase	142
648930276	333	38.59	12	320	14	321	2.0e-64	239	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
648930277	327	41.21	5	327	20	345	6.0e-74	271	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
648930278	332	41.98	1	331	7	345	2.0e-64	239	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
648930279	521	56.06	15	515	2	501	0.0e+00	648	COG3845	ABC-type uncharacterized transport system, ATPase component	501
648930280	368	40.06	1	356	3	350	7.0e-72	264	COG4603	ABC-type uncharacterized transport system, permease component	356
648930281	322	55.14	1	321	3	304	5.0e-80	291	COG1079	ABC-type uncharacterized transport system, permease component	304
648930282	131	47.58	6	128	7	130	3.0e-35	140	COG0295	Cytidine deaminase	134
648930283	270	46.04	6	267	3	262	3.0e-67	248	COG0005	Purine nucleoside phosphorylase	262
648930284	259	35.92	10	253	5	227	2.0e-47	182	COG0274	Deoxyribose-phosphate aldolase	228
648930285	438	48.17	1	436	2	433	0.0e+00	478	COG0213	Thymidine phosphorylase	435
648930286	407	57.84	1	406	1	393	0.0e+00	547	COG1015	Phosphopentomutase	397
648930287	333	38.67	8	330	12	342	3.0e-79	288	COG1816	Adenosine deaminase	345
648930289	209	61.9	1	209	1	210	2.0e-86	312	COG0035	Uracil phosphoribosyltransferase	210
648930291	499	30.4	19	488	2	459	1.0e-83	303	COG1109	Phosphomannomutase	464
648930292	327	35.15	3	327	1	306	8.0e-58	217	COG2017	Galactose mutarotase or related enzyme	308
648930293	343	35.47	6	341	3	310	4.0e-66	245	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
648930294	205	18.5	4	191	3	201	1.0e-18	86.1	COG1011	FMN phosphatase YigB, HAD superfamily	229
648930295	307	27.24	9	296	13	290	7.0e-27	114	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
648930296	392	46.46	5	388	1	393	5.0e-121	428	COG0282	Acetate kinase	396
648930297	473	26.16	183	452	23	321	3.0e-43	170	COG0280	Phosphotransacetylase	327
648930298	194	19.49	1	193	2	185	3.0e-15	75.2	COG4961	Flp pilus assembly protein TadG	185
648930301	59	40.74	1	54	1	54	5.0e-07	46.4	COG3847	Flp pilus assembly protein, pilin Flp	58
648930303	60	50	1	58	1	58	1.0e-08	51.8	COG3847	Flp pilus assembly protein, pilin Flp	58
648930306	56	60.71	1	56	1	56	4.0e-10	56.4	COG3847	Flp pilus assembly protein, pilin Flp	58
648930307	169	45.51	7	162	10	163	6.0e-23	100	COG4960	Flp pilus assembly protein, protease CpaA	168
648930308	256	38.91	1	234	1	238	8.0e-42	163	COG3745	Flp pilus assembly protein CpaB	276
648930309	482	41.58	29	482	4	455	1.0e-105	377	COG4964	Flp pilus assembly protein, secretin CpaC	455
648930310	237	36.36	19	227	16	221	1.0e-33	136	COG5461	Type IV pilus biogenesis protein CpaD/CtpE	224
648930311	429	48.29	167	429	104	362	2.0e-71	263	COG4963	Flp pilus assembly protein, ATPase CpaE	366
648930312	491	59.17	89	448	1	355	0.0e+00	482	COG4962	Pilus assembly protein, ATPase of CpaF family	355
648930313	340	35.67	13	340	1	309	8.0e-60	224	COG4965	Flp pilus assembly protein TadB	309
648930314	326	29.08	24	324	20	319	2.0e-29	123	COG2064	Pilus assembly protein TadC	320
648930315	246	36.73	1	242	2	245	8.0e-33	133	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
648930317	205	29.63	53	187	10	134	6.0e-13	67.7	COG3415	Transposase	138
648930318	464	39.66	15	460	19	484	8.0e-117	414	COG0260	Leucyl aminopeptidase	485
648930319	116	32.22	25	114	16	104	7.0e-06	42.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
648930321	394	29.38	41	388	77	429	5.0e-66	245	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
648930322	196	55.95	23	189	1	168	6.0e-63	233	COG0242	Peptide deformylase	168
648930323	210	36.84	1	209	2	203	2.0e-28	119	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
648930324	313	49.52	2	310	1	307	2.0e-108	385	COG0223	Methionyl-tRNA formyltransferase	307
648930325	179	36.21	9	178	3	171	4.0e-24	104	COG3153	Predicted N-acetyltransferase YhbS	171
648930326	271	47.76	1	245	1	244	2.0e-83	302	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
648930327	257	30.92	1	257	12	272	3.0e-32	132	COG5473	Uncharacterized membrane protein	290
648930328	143	27.2	14	135	7	120	5.0e-08	50.3	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
648930329	391	34.9	1	388	9	409	1.0e-77	283	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648930334	282	49.65	5	282	1	270	1.0e-81	296	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
648930336	287	30.03	3	287	2	291	2.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
648930337	246	25.21	25	242	4	229	2.0e-18	86.5	COG1011	FMN phosphatase YigB, HAD superfamily	229
648930338	295	55.68	25	295	2	265	7.0e-87	314	COG0548	Acetylglutamate kinase	265
648930340	215	48.44	18	209	2	192	7.0e-58	217	COG0218	GTP-binding protein EngB required for normal cell division	200
648930341	214	26.16	17	183	19	190	8.0e-24	103	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
648930342	603	38.62	270	595	6	314	6.0e-73	268	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
648930343	131	35.58	1	102	4	105	5.0e-10	56.8	COG0594	RNase P protein component	117
648930344	271	30.73	38	214	6	184	3.0e-18	85.7	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
648930345	480	37.31	12	456	6	454	2.0e-102	366	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
648930346	491	25.24	183	489	28	328	1.0e-28	121	COG0642	Signal transduction histidine kinase	336
648930354	328	23.92	1	327	5	341	3.0e-21	95.8	COG3500	Phage protein D	350
648930355	68	44.26	4	63	5	65	4.0e-10	56.5	COG5004	P2-like prophage tail protein X	70
648930356	151	24.16	3	151	1	146	2.0e-09	55	COG3499	Phage protein U	147
648930362	399	26.52	7	387	5	393	7.0e-32	131	COG3497	Phage tail sheath protein FI	394
648930369	285	31.29	5	263	10	282	5.0e-21	95.1	COG3948	Phage-related baseplate assembly protein	306
648930375	146	39.55	1	130	1	131	1.0e-23	102	COG4387	Mu-like prophage protein gp36	139
648930380	299	45.13	1	297	1	308	2.0e-85	309	COG4397	Mu-like prophage major head subunit gpT	308
648930382	325	28.77	1	323	2	355	5.0e-28	118	COG4388	Mu-like prophage I protein	357
648930385	527	31.1	27	527	21	517	1.0e-77	284	COG4383	Mu-like prophage protein gp29	517
648930386	559	35.35	36	546	1	502	3.0e-111	396	COG4373	Mu-like prophage FluMu protein gp28	509
648930393	399	27.63	186	332	8	159	3.0e-08	53.1	COG3409	Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases	185
648930401	174	45.51	15	169	14	169	3.0e-36	144	COG4396	Mu-like prophage host-nuclease inhibitor protein Gam	170
648930418	265	21.03	24	251	4	221	3.0e-09	56.1	COG2801	Transposase InsO and inactivated derivatives	232
648930421	205	29.63	53	187	10	134	6.0e-13	67.7	COG3415	Transposase	138
648930427	326	25.39	110	302	58	231	1.0e-11	64.2	COG2801	Transposase InsO and inactivated derivatives	232
648930429	284	53.21	3	263	1	265	4.0e-96	344	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
648930430	263	52.44	1	246	1	245	5.0e-83	300	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
648930431	467	23.44	103	451	42	431	6.0e-33	135	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
648930435	526	56.14	1	523	1	525	0.0e+00	600	COG4650	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain	531
648930436	343	29.85	8	342	2	328	1.0e-58	220	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
648930437	435	23.74	1	430	10	431	2.0e-38	154	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648930440	276	38.93	1	276	2	281	7.0e-49	187	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648930441	333	54.97	1	329	1	338	3.0e-124	438	COG3839	ABC-type sugar transport system, ATPase component	338
648930442	257	39.85	3	254	2	250	1.0e-41	163	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648930443	496	40.88	23	492	3	473	1.0e-116	413	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
648930444	126	38.21	7	126	1	123	1.0e-16	78.5	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
648930446	263	38.33	13	248	13	251	1.0e-41	163	COG1484	DNA replication protein DnaC	254
648930447	526	26.77	22	289	7	257	2.0e-17	84.3	COG4584	Transposase	278
648930448	227	25.39	11	203	58	231	7.0e-12	64.2	COG2801	Transposase InsO and inactivated derivatives	232
648930449	805	26.64	197	641	5	447	2.0e-46	181	COG5002	Signal transduction histidine kinase	459
648930450	348	37.72	13	344	1	333	8.0e-79	287	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
648930452	380	21.7	54	371	22	332	2.0e-38	153	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648930453	171	30.32	1	155	5	156	1.0e-16	79.6	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648930454	443	35.09	61	438	1	375	1.0e-62	234	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648930455	435	39.12	16	423	21	424	2.0e-118	419	COG0141	Histidinol dehydrogenase	425
648930456	253	39.37	8	251	1	251	2.0e-37	149	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648930457	337	30.99	1	329	2	350	5.0e-54	204	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
648930459	392	39.53	8	389	6	378	2.0e-98	352	COG2721	Altronate dehydratase	381
648930460	330	39.52	1	325	6	339	5.0e-79	288	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
648930461	349	36.56	27	345	14	330	1.0e-58	220	COG2855	Uncharacterized membrane protein YadS	334
648930474	391	31.04	5	385	2	387	6.0e-44	171	COG0183	Acetyl-CoA acetyltransferase	392
648930475	470	29.39	1	468	10	533	4.0e-74	272	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648930476	210	44.81	25	207	3	182	1.0e-25	109	COG1268	Biotin transporter BioY	184
648930477	204	27.52	1	195	2	212	9.0e-12	63.9	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
648930478	259	43.24	26	238	6	227	1.0e-46	179	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
648930480	469	27.47	11	461	1	459	5.0e-74	272	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
648930481	198	23.04	1	196	1	204	7.0e-11	60.7	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
648930484	309	29.01	11	294	5	291	1.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
648930485	191	40.72	7	191	59	252	2.0e-46	179	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
648930486	262	30.19	12	255	7	271	4.0e-39	155	COG3246	Uncharacterized conserved protein, DUF849 family	298
648930487	438	44.62	1	437	10	444	0.0e+00	477	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
648930489	119	39.13	1	113	3	115	5.0e-26	109	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
648930490	588	30.16	370	557	45	215	1.0e-24	107	COG2114	Adenylate cyclase, class 3	227
648930491	386	31.11	12	385	19	406	3.0e-57	216	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648930492	527	32.07	1	510	7	535	7.0e-77	281	COG0747	ABC-type transport system, periplasmic component	556
648930493	324	45.06	1	323	1	317	1.0e-81	296	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648930494	327	43.64	37	327	15	287	3.0e-65	242	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648930495	578	50.98	1	563	3	537	0.0e+00	677	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
648930496	340	42.94	1	338	1	329	9.0e-123	433	COG1087	UDP-glucose 4-epimerase	329
648930497	599	43.79	1	583	1	574	0.0e+00	634	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
648930498	93	31.63	1	92	20	117	1.0e-09	55	COG3255	Putative sterol carrier protein	134
648930499	283	34.48	5	257	4	258	2.0e-47	183	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
648930500	323	25.23	1	319	1	308	2.0e-36	146	COG0451	Nucleoside-diphosphate-sugar epimerase	314
648930501	391	29.95	66	390	18	381	2.0e-53	203	COG0372	Citrate synthase	390
648930505	318	35.65	2	317	55	381	6.0e-68	251	COG0372	Citrate synthase	390
648930507	311	33.11	2	301	29	329	2.0e-67	249	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648930508	314	30.2	21	154	21	169	1.0e-18	87.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
648930510	534	43.09	1	534	2	538	0.0e+00	484	COG2303	Choline dehydrogenase or related flavoprotein	542
648930513	249	41.3	2	248	1	224	5.0e-45	174	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
648930514	155	43.14	1	153	3	154	7.0e-32	129	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648930515	370	53.93	4	368	3	363	0.0e+00	481	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
648930517	316	37.73	3	314	1	317	3.0e-60	225	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
648930518	123	44.74	10	121	1	114	4.0e-24	103	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
648930519	302	52.55	25	298	3	275	1.0e-89	323	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
648930520	403	21.75	50	378	1	345	7.0e-15	75.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648930521	414	49.88	1	409	1	391	3.0e-112	398	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
648930525	149	57.72	1	149	1	148	4.0e-51	193	COG0756	dUTPase	148
648930526	223	30.56	8	220	2	216	4.0e-40	157	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
648930527	319	60	11	313	1	300	3.0e-109	388	COG0031	Cysteine synthase	300
648930529	105	59.43	1	105	1	106	2.0e-30	124	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
648930530	316	37.03	12	316	1	305	4.0e-57	215	COG0010	Arginase family enzyme	305
648930531	363	43.86	5	341	1	314	1.0e-97	349	COG0180	Tryptophanyl-tRNA synthetase	314
648930532	522	42.52	1	505	7	509	4.0e-98	352	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
648930533	945	42.44	42	932	1	867	0.0e+00	924	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
648930536	189	29.63	6	189	1	182	1.0e-27	116	COG2840	DNA-nicking endonuclease, Smr domain	184
648930537	373	34.77	1	358	4	365	1.0e-75	276	COG2821	Membrane-bound lytic murein transglycosylase	373
648930538	244	36.75	11	244	53	281	9.0e-52	197	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
648930539	172	40.97	1	144	1	144	2.0e-27	115	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
648930540	345	20.22	3	331	17	366	6.0e-39	155	COG4763	Uncharacterized membrane protein YcfT	388
648930542	793	52.85	181	793	1	593	0.0e+00	760	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
648930544	508	54.08	14	499	1	485	0.0e+00	597	COG0606	Predicted ATPase with chaperone activity	490
648930546	796	34.15	233	514	61	335	5.0e-38	153	COG0642	Signal transduction histidine kinase	336
648930548	306	45.28	39	303	32	289	2.0e-62	232	COG3176	Putative hemolysin	292
648930549	104	52.08	1	95	1	96	2.0e-27	113	COG5470	Uncharacterized conserved protein, DUF1330 family	96
648930550	732	46.31	88	724	7	643	0.0e+00	583	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
648930551	244	32.58	23	243	12	223	2.0e-38	152	COG1451	Predicted metal-dependent hydrolase	223
648930554	547	65.76	3	407	2	407	0.0e+00	649	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
648930555	388	42.13	1	388	24	411	3.0e-110	392	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
648930556	212	45.81	10	211	3	192	5.0e-60	224	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
648930557	237	55.46	1	237	8	230	1.0e-77	282	COG0689	Ribonuclease PH	230
648930558	349	47.25	6	349	4	341	9.0e-96	343	COG1420	Transcriptional regulator of heat shock response	346
648930559	269	49.8	1	253	2	248	4.0e-72	264	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
648930561	165	41.29	9	163	1	155	8.0e-46	176	COG1952	Preprotein translocase subunit SecB	157
648930563	444	22.29	91	432	1	334	1.0e-22	101	COG0642	Signal transduction histidine kinase	336
648930564	192	67.22	14	192	3	182	5.0e-66	243	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
648930568	563	26.93	186	553	57	406	3.0e-27	117	COG0840	Methyl-accepting chemotaxis protein	408
648930569	328	58.68	19	306	2	283	1.0e-100	359	COG1072	Panthothenate kinase	283
648930570	107	55.56	6	95	1	90	1.0e-21	94.9	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
648930571	259	67.19	3	258	2	256	1.0e-114	406	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
648930572	247	52.07	1	242	2	241	5.0e-83	300	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
648930573	217	50.23	1	217	2	204	2.0e-74	271	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
648930575	197	66.15	1	195	3	195	8.0e-82	296	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
648930576	282	42.61	55	282	13	238	6.0e-56	211	COG0284	Orotidine-5'-phosphate decarboxylase	240
648930577	361	39.64	13	336	1	330	4.0e-82	298	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
648930578	319	35.88	16	314	26	305	1.0e-51	197	COG0010	Arginase family enzyme	305
648930579	156	32.88	1	143	3	148	2.0e-19	89	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648930580	305	35.71	133	296	1	168	1.0e-40	160	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
648930582	438	43.28	1	434	4	422	3.0e-110	392	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
648930583	328	54.39	1	283	1	285	3.0e-109	388	COG0777	Acetyl-CoA carboxylase beta subunit	294
648930584	277	44.4	4	271	2	263	5.0e-82	297	COG0159	Tryptophan synthase alpha chain	265
648930587	404	72.7	10	401	1	391	0.0e+00	710	COG0133	Tryptophan synthase beta chain	396
648930588	219	47.39	4	214	2	208	2.0e-57	215	COG0135	Phosphoribosylanthranilate isomerase	208
648930589	784	57.37	29	459	7	425	0.0e+00	577	COG0281	Malic enzyme	432
648930590	906	46.79	14	898	4	843	0.0e+00	917	COG0249	DNA mismatch repair ATPase MutS	843
648930592	172	54.25	17	169	12	164	1.0e-45	175	COG5488	Uncharacterized membrane protein	164
648930593	272	53.59	43	251	1	209	4.0e-77	281	COG0177	Endonuclease III	211
648930596	127	32.26	1	122	11	133	3.0e-24	103	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
648930598	168	33.54	13	168	1	147	8.0e-37	146	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
648930599	407	43.45	1	405	2	411	6.0e-116	411	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
648930600	270	61.87	4	260	3	259	4.0e-110	391	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
648930601	169	49.67	19	169	19	171	7.0e-48	183	COG3807	SH3-like domain	171
648930603	328	46.95	4	326	1	324	5.0e-98	351	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
648930604	239	38.24	1	236	13	238	2.0e-45	175	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
648930605	195	37.88	1	194	2	196	1.0e-41	162	COG0237	Dephospho-CoA kinase	201
648930606	281	38.41	6	278	8	283	4.0e-75	274	COG0169	Shikimate 5-dehydrogenase	283
648930607	197	34.34	1	197	3	192	3.0e-46	178	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
648930608	280	45.49	7	270	3	267	6.0e-84	304	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
648930610	334	42.9	1	333	11	347	6.0e-96	344	COG0407	Uroporphyrinogen-III decarboxylase	352
648930611	142	57.93	1	142	5	149	4.0e-47	180	COG1981	Uncharacterized membrane protein	149
648930612	418	73.44	1	418	4	420	0.0e+00	717	COG1158	Transcription termination factor Rho	422
648930613	193	30.65	5	187	3	184	8.0e-26	110	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648930614	453	41.58	7	453	3	454	2.0e-129	456	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
648930615	625	58.35	7	620	4	619	0.0e+00	913	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
648930616	217	37.62	18	211	15	211	5.0e-43	167	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
648930617	274	38.35	8	271	2	259	1.0e-57	216	COG1192	Cellulose biosynthesis protein BcsQ	259
648930618	304	36.15	40	295	5	240	1.0e-32	133	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
648930619	347	24.84	22	339	18	333	8.0e-42	164	COG1466	DNA polymerase III, delta subunit	334
648930620	187	32.18	17	180	5	166	6.0e-18	83.9	COG5468	Predicted secreted (periplasmic) protein	172
648930621	895	45.64	31	895	3	814	0.0e+00	1001	COG0495	Leucyl-tRNA synthetase	814
648930623	224	44.74	4	223	2	228	9.0e-73	266	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
648930624	519	55.01	1	449	1	446	0.0e+00	575	COG0541	Signal recognition particle GTPase	451
648930625	107	35.35	10	107	3	101	3.0e-15	73.8	COG1605	Chorismate mutase	101
648930626	118	65.17	2	90	1	87	8.0e-28	115	COG0228	Ribosomal protein S16	87
648930627	179	43.93	1	169	1	172	4.0e-41	160	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
648930629	233	56.71	3	232	1	230	1.0e-94	339	COG0336	tRNA G37 N-methylase TrmD	240
648930634	153	62.07	1	116	3	113	2.0e-39	154	COG0335	Ribosomal protein L19	115
648930636	470	57.91	3	467	1	422	0.0e+00	639	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
648930638	185	32.65	24	167	1	146	6.0e-25	107	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
648930639	466	24.05	6	163	8	155	4.0e-10	60.1	COG4961	Flp pilus assembly protein TadG	185
648930641	645	44.66	67	627	1	528	0.0e+00	690	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
648930645	200	28.16	2	197	1	205	1.0e-25	109	COG0625	Glutathione S-transferase	211
648930648	387	42.77	18	360	1	320	8.0e-82	297	COG0523	GTPase, G3E family	323
648930651	412	39.2	9	401	1	387	3.0e-78	285	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
648930652	284	27.3	1	275	2	255	3.0e-34	138	COG0300	Short-chain dehydrogenase	265
648930654	191	57.29	1	191	1	184	8.0e-61	226	COG2096	Cob(I)alamin adenosyltransferase	184
648930655	226	30	1	220	1	212	1.0e-26	113	COG0705	Membrane associated serine protease, rhomboid family	228
648930656	249	50	1	249	1	260	7.0e-71	260	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
648930657	310	57.1	1	310	1	311	4.0e-83	301	COG2025	Electron transfer flavoprotein, alpha subunit	313
648930658	295	56.64	5	289	1	286	3.0e-101	361	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
648930667	221	31.78	81	186	17	117	2.0e-10	59.5	COG0526	Thiol-disulfide isomerase or thioredoxin	127
648930668	522	55.56	59	517	1	458	0.0e+00	622	COG0165	Argininosuccinate lyase	459
648930670	424	49.25	1	394	1	394	8.0e-126	443	COG0019	Diaminopimelate decarboxylase	394
648930673	187	48.86	1	175	4	176	8.0e-59	219	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
648930675	219	56.28	1	215	1	215	7.0e-85	306	COG2884	ABC-type ATPase involved in cell division	223
648930676	322	27.42	24	320	10	296	9.0e-41	161	COG2177	Cell division protein FtsX	297
648930677	245	23	40	242	12	216	6.0e-16	77.9	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
648930678	261	26.84	11	236	5	230	4.0e-27	115	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
648930679	194	48.89	16	194	7	186	8.0e-54	203	COG3703	Cation transport regulator ChaC	190
648930681	336	27.22	2	331	19	338	6.0e-27	115	COG4093	Uncharacterized protein	338
648930682	153	17.73	1	134	9	147	9.0e-08	50	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
648930685	296	40.21	10	293	1	281	2.0e-65	242	COG2301	Citrate lyase beta subunit	283
648930686	67	63.24	1	67	3	70	6.0e-22	95.9	COG5515	Uncharacterized protein	70
648930687	278	25.37	5	247	29	288	5.0e-16	78.4	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
648930688	214	25.24	9	207	4	204	3.0e-24	105	COG2834	Outer membrane lipoprotein-sorting protein	211
648930689	928	29.74	26	921	4	854	0.0e+00	536	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
648930690	407	30.1	22	403	16	389	1.0e-60	227	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
648930691	86	46.25	7	86	5	84	2.0e-14	70.5	COG5508	Uncharacterized protein	84
648930692	345	35.21	7	282	33	301	4.0e-49	188	COG0501	Zn-dependent protease with chaperone function	302
648930693	462	38.06	123	461	1	353	2.0e-75	276	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
648930695	597	42.68	3	564	2	566	0.0e+00	517	COG5360	Uncharacterized conserved protein, heparinase superfamily	566
648930697	538	61.33	15	538	1	515	0.0e+00	737	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
648930698	467	36.68	11	464	3	432	3.0e-86	312	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
648930700	1602	47.02	1	1602	1	1592	0.0e+00	1676	COG2902	NAD-specific glutamate dehydrogenase	1592
648930701	188	29.29	44	181	38	177	3.0e-19	88.3	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
648930702	315	28.09	1	313	1	342	4.0e-71	261	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
648930703	201	55.72	1	201	1	189	2.0e-75	275	COG0066	3-isopropylmalate dehydratase small subunit	191
648930709	227	40.35	6	227	3	227	3.0e-46	178	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648930710	174	50.59	5	174	50	216	1.0e-48	185	COG3786	L,D-peptidoglycan transpeptidase YkuD, ErfK/YbiS/YcfS/YnhG family	217
648930711	321	44.29	20	296	1	272	1.0e-80	293	COG0253	Diaminopimelate epimerase	272
648930712	459	38.36	1	418	3	436	1.0e-124	440	COG0621	tRNA A37 methylthiotransferase MiaB	437
648930713	371	50.74	41	369	4	340	9.0e-105	373	COG0552	Signal recognition particle GTPase	340
648930714	149	56.67	8	148	5	153	6.0e-43	166	COG3542	Predicted sugar epimerase, cupin superfamily	162
648930717	260	25.61	15	233	22	252	7.0e-22	97.6	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648930719	318	34.15	36	116	8	88	1.0e-08	54.2	COG1605	Chorismate mutase	101
648930720	373	41.27	16	373	2	354	9.0e-88	317	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
648930721	306	40.56	4	288	1	279	1.0e-79	289	COG0287	Prephenate dehydrogenase	279
648930724	310	41.01	12	285	1	262	2.0e-58	219	COG0142	Geranylgeranyl pyrophosphate synthase	322
648930725	410	47.52	104	383	2	283	1.0e-84	306	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
648930728	61	54.39	1	57	1	57	2.0e-13	67.2	COG0333	Ribosomal protein L32	57
648930730	214	43.08	19	212	1	180	7.0e-48	183	COG2917	Intracellular septation protein A	180
648930731	242	41.2	1	237	4	250	1.0e-47	183	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648930732	416	49.38	27	416	1	391	3.0e-97	349	COG0183	Acetyl-CoA acetyltransferase	392
648930733	192	58.38	1	188	3	193	5.0e-57	214	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
648930734	143	44.29	1	140	5	141	1.0e-25	109	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
648930735	531	40.04	3	531	1	539	0.0e+00	493	COG0405	Gamma-glutamyltranspeptidase	539
648930742	118	69.49	1	118	1	118	4.0e-40	156	COG0292	Ribosomal protein L20	118
648930743	65	52.31	1	65	1	65	2.0e-10	57.2	COG0291	Ribosomal protein L35	65
648930744	330	32.13	3	328	1	326	3.0e-48	185	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
648930745	546	34.8	11	542	4	531	1.0e-111	397	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648930746	377	30.4	13	376	2	373	5.0e-61	228	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
648930748	208	40	3	203	6	207	7.0e-49	187	COG5588	Uncharacterized protein	207
648930749	264	38.26	32	256	50	279	2.0e-30	126	COG5486	Predicted metal-binding membrane protein	283
648930750	257	33.88	4	239	3	241	4.0e-32	131	COG2186	DNA-binding transcriptional regulator, FadR family	241
648930751	125	27.03	1	110	9	117	6.0e-11	59.9	COG3011	Predicted thiol-disulfide oxidoreductase YuxK, DCC family	137
648930753	381	58.89	7	381	2	377	0.0e+00	479	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
648930754	192	45.56	10	189	1	180	4.0e-45	174	COG3709	Ribose 1,5-bisphosphokinase PhnN	192
648930755	949	20.44	1	532	4	500	7.0e-12	66.6	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
648930757	352	44.84	14	352	34	364	4.0e-87	314	COG3490	Uncharacterized protein	366
648930758	357	29.33	1	357	4	359	4.0e-48	185	COG3489	Predicted periplasmic lipoprotein	359
648930759	510	60.91	30	510	1	481	0.0e+00	667	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
648930760	421	63.77	8	421	34	446	0.0e+00	534	COG3487	Uncharacterized iron-regulated protein	446
648930762	155	48.65	1	148	3	148	7.0e-32	130	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
648930763	272	36.7	32	214	1	185	1.0e-40	160	COG0518	GMP synthase - Glutamine amidotransferase domain	198
648930764	511	35.87	54	511	15	458	4.0e-85	309	COG5361	Uncharacterized conserved protein	458
648930766	1149	63.85	1	1148	3	1148	0.0e+00	1828	COG1038	Pyruvate carboxylase	1149
648930767	232	46.77	170	231	4	65	2.0e-13	69.6	COG2771	DNA-binding transcriptional regulator, CsgD family	65
648930769	125	40	5	94	9	97	4.0e-19	86.9	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
648930771	114	42.42	8	69	5	68	3.0e-08	50.2	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
648930773	194	51.23	10	171	1	162	3.0e-51	194	COG1329	RNA polymerase-interacting regulator, CarD/CdnL/TRCF family	166
648930774	291	39.93	9	282	70	336	6.0e-63	234	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
648930775	493	48.31	28	493	8	479	0.0e+00	462	COG4784	Putative Zn-dependent protease	479
648930778	414	25.18	117	357	11	272	1.0e-10	61.4	COG4974	Site-specific recombinase XerD	300
648930780	395	24.66	16	158	37	180	3.0e-09	56.5	COG3886	HKD family nuclease	198
648930782	234	26.02	43	231	20	212	1.0e-21	97.1	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
648930798	140	26.67	7	137	25	153	5.0e-06	43.9	COG4382	Mu-like prophage protein gp16	170
648930812	523	26.3	62	504	68	514	2.0e-33	137	COG4383	Mu-like prophage protein gp29	517
648930821	167	32.06	16	146	3	119	2.0e-11	61.9	COG4387	Mu-like prophage protein gp36	139
648930824	440	25.59	3	421	2	383	4.0e-35	142	COG3497	Phage tail sheath protein FI	394
648930831	333	26.45	5	331	5	340	4.0e-29	122	COG3500	Phage protein D	350
648930832	178	25.57	15	173	7	178	3.0e-11	61.5	COG4540	Phage P2 baseplate assembly protein gpV	184
648930844	263	29.2	10	263	2	271	1.0e-26	113	COG0338	Site-specific DNA-adenine methylase	274
648930848	526	28.15	22	289	7	257	2.0e-17	84	COG4584	Transposase	278
648930849	263	38.33	13	248	13	251	1.0e-41	163	COG1484	DNA replication protein DnaC	254
648930852	236	43.04	2	228	1	227	4.0e-55	207	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648930853	746	18.63	335	627	31	345	6.0e-07	49.9	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
648930866	375	43.68	1	371	2	370	2.0e-88	319	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
648930867	524	26.83	5	477	2	426	8.0e-49	188	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
648930878	186	34.33	1	183	2	202	7.0e-20	90.6	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
648930884	3511	28.03	3153	3508	112	482	7.0e-12	68.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
648930898	927	22.38	344	902	127	669	7.0e-56	213	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
648930901	322	25	94	319	49	291	6.0e-10	58.3	COG4974	Site-specific recombinase XerD	300
648930910	142	37.14	4	141	5	143	1.0e-20	92.3	COG3793	Tellurite resistance protein	144
648930926	373	18.99	9	358	14	281	2.0e-23	103	COG0863	DNA modification methylase	302
648930927	83	52	3	77	8	82	2.0e-16	77.3	COG3750	Uncharacterized conserved protein, UPF0335 family	85
648930932	200	22.03	27	195	1	172	7.0e-10	57.6	COG0250	Transcription antitermination factor NusG	178
648930935	596	25.09	14	573	2	525	3.0e-62	233	COG4626	Phage terminase-like protein, large subunit, contains N-terminal HTH domain	546
648930936	427	37.28	20	401	6	387	5.0e-80	291	COG4695	Phage portal protein BeeE	398
648930937	283	27.81	41	206	27	191	4.0e-30	125	COG0740	ATP-dependent protease ClpP, protease subunit	200
648930938	471	42.82	42	471	1	420	4.0e-107	382	COG4653	Predicted phage phi-C31 gp36 major capsid-like protein	422
648930964	280	28.47	14	268	2	271	4.0e-27	115	COG0338	Site-specific DNA-adenine methylase	274
648930965	771	31.75	278	771	166	658	7.0e-72	265	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
648930966	204	32.72	13	173	1	158	1.0e-21	96.9	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
648930967	176	31.33	1	162	5	164	7.0e-16	77	COG1495	Disulfide bond formation protein DsbB	170
648930969	165	56.82	30	161	6	136	2.0e-38	151	COG3824	Predicted Zn-dependent protease, minimal metalloprotease (MMP)-like domain	136
648930970	179	54.86	1	175	1	171	3.0e-53	201	COG0221	Inorganic pyrophosphatase	171
648930972	193	24.66	24	167	7	148	4.0e-07	48.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
648930975	261	43.73	1	259	1	228	3.0e-36	145	COG0670	Integral membrane protein, interacts with FtsH	233
648930976	855	41.89	12	855	5	829	0.0e+00	726	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
648930977	263	58.77	26	251	1	228	8.0e-87	313	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
648930978	209	32.51	26	203	10	212	5.0e-21	94.6	COG2755	Lysophospholipase L1 or related esterase	216
648930979	350	39.09	1	350	1	316	1.0e-78	287	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
648930980	178	39.66	3	176	2	178	7.0e-33	133	COG1514	2'-5' RNA ligase	180
648930982	614	21.63	222	614	10	376	8.0e-23	102	COG0840	Methyl-accepting chemotaxis protein	408
648930983	423	25.31	38	417	5	378	1.0e-29	124	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648930984	261	22.18	15	260	5	282	1.0e-13	70.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648930985	213	36.12	1	210	56	282	3.0e-40	158	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
648930987	322	28.21	1	318	1	310	4.0e-33	135	COG0679	Predicted permease	311
648930989	285	20.45	30	241	29	242	1.0e-05	44.2	COG3907	Membrane-associated enzyme, PAP2 (acid phosphatase) superfamily	249
648930991	155	46.58	5	148	4	149	3.0e-47	180	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
648930992	247	31.09	8	243	1	212	3.0e-48	185	COG0602	Organic radical activating enzyme	212
648930993	124	42.19	1	119	2	127	3.0e-28	116	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
648930994	229	44.14	1	220	3	222	1.0e-71	262	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
648930996	200	39.5	1	195	17	209	7.0e-47	180	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
648930997	223	56.68	7	223	6	221	2.0e-42	166	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
648930998	255	41.2	1	232	36	268	2.0e-45	176	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
648931000	219	26.12	59	189	2	127	7.0e-12	64.2	COG0526	Thiol-disulfide isomerase or thioredoxin	127
648931001	258	40.96	1	246	7	252	9.0e-53	200	COG5429	Uncharacterized protein	261
648931002	295	38.62	1	289	8	295	4.0e-65	241	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
648931003	277	34.15	1	276	2	279	4.0e-42	165	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648931005	168	39.51	9	167	58	216	2.0e-25	108	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
648931006	341	28.96	17	340	15	330	5.0e-40	158	COG3239	Fatty acid desaturase	343
648931007	407	37.2	7	401	3	404	1.0e-79	290	COG0004	Ammonia channel protein AmtB	409
648931008	441	35.04	41	434	5	405	9.0e-81	294	COG0004	Ammonia channel protein AmtB	409
648931009	116	65.18	5	116	1	112	5.0e-38	149	COG0347	Nitrogen regulatory protein PII	112
648931010	183	53.07	3	181	4	182	2.0e-58	218	COG3803	Uncharacterized conserved protein, DUF924 family	182
648931011	77	44.74	1	75	2	77	1.0e-17	81.5	COG0425	TusA-related sulfurtransferase	78
648931012	101	45.74	1	94	2	95	3.0e-27	113	COG2154	Pterin-4a-carbinolamine dehydratase	101
648931014	891	63.54	6	890	1	861	0.0e+00	1244	COG1048	Aconitase A	861
648931015	254	31.78	18	230	7	216	1.0e-34	140	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
648931016	380	14.34	99	361	6	277	3.0e-10	59.6	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
648931017	307	25.33	5	301	1	297	4.0e-30	125	COG0583	DNA-binding transcriptional regulator, LysR family	297
648931019	951	32.28	24	951	1	852	0.0e+00	918	COG1049	Aconitase B	852
648931020	345	37.77	18	332	7	328	1.0e-40	160	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
648931021	343	40.06	1	326	2	326	3.0e-45	175	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
648931022	259	42.46	4	255	3	254	6.0e-76	277	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
648931023	320	25.08	1	304	1	318	2.0e-36	146	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
648931024	206	27.72	2	199	1	200	6.0e-34	137	COG0625	Glutathione S-transferase	211
648931026	540	35.98	16	538	1	520	5.0e-129	455	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
648931028	471	23.4	44	448	10	407	4.0e-26	113	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
648931029	283	33.33	6	278	9	254	9.0e-30	124	COG4544	Uncharacterized conserved protein	260
648931030	530	20.75	54	480	1	353	8.0e-16	78.8	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
648931031	1135	39.32	19	1062	2	1060	0.0e+00	1035	COG0587	DNA polymerase III, alpha subunit	1139
648931032	133	37.01	3	129	2	127	7.0e-28	116	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
648931039	261	71.65	1	261	1	261	1.0e-114	405	COG4813	Trehalose utilization protein	261
648931040	356	32.39	5	349	1	335	4.0e-53	202	COG0673	Predicted dehydrogenase	342
648931042	183	55.76	7	171	1	163	7.0e-51	193	COG3760	Uncharacterized protein	164
648931043	330	42.67	23	329	3	304	2.0e-84	305	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
648931044	226	45.29	8	226	2	221	1.0e-51	196	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
648931045	71	60	17	71	1	55	2.0e-15	74.1	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
648931052	664	23.64	25	653	17	594	1.0e-39	158	COG5525	Phage terminase, large subunit GpA	611
648931054	501	26.06	7	484	1	477	1.0e-47	184	COG5511	Bacteriophage capsid protein	492
648931056	108	30.84	1	106	2	105	1.0e-10	58.1	COG5471	Predicted phage recombinase, RecA/RadA family	107
648931059	183	28.96	29	182	2	183	2.0e-10	58.8	COG4540	Phage P2 baseplate assembly protein gpV	184
648931061	140	42.72	1	103	3	97	2.0e-16	78.1	COG3628	Phage baseplate assembly protein W	116
648931062	283	34.04	3	268	9	291	1.0e-26	113	COG3948	Phage-related baseplate assembly protein	306
648931068	482	28.57	87	470	11	394	2.0e-45	177	COG3497	Phage tail sheath protein FI	394
648931069	169	32.93	4	168	6	168	4.0e-20	91.1	COG3498	Phage tail tube protein FII	169
648931072	139	26.4	1	125	1	123	6.0e-11	60	COG3499	Phage protein U	147
648931073	373	24.49	1	327	5	339	1.0e-32	133	COG3500	Phage protein D	350
648931075	321	36.11	1	191	3	206	1.0e-43	170	COG3179	Predicted chitinase	206
648931079	301	37.5	15	301	6	293	2.0e-55	209	COG1175	ABC-type sugar transport system, permease component	295
648931080	291	34.97	6	290	2	281	3.0e-54	205	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648931081	369	51.52	1	363	1	338	2.0e-120	425	COG3839	ABC-type sugar transport system, ATPase component	338
648931082	492	24.95	1	489	6	536	7.0e-71	261	COG2303	Choline dehydrogenase or related flavoprotein	542
648931083	252	32.16	1	248	4	251	8.0e-33	134	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648931084	549	44.07	1	528	4	539	0.0e+00	497	COG2303	Choline dehydrogenase or related flavoprotein	542
648931087	335	34.64	5	332	1	329	4.0e-71	261	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
648931091	365	29.04	41	365	19	347	3.0e-49	189	COG3405	Endo-1,4-beta-D-glucanase Y	360
648931093	756	26.97	94	534	10	408	6.0e-52	199	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
648931095	205	29.63	53	187	10	134	6.0e-13	67.7	COG3415	Transposase	138
648931096	296	24.83	4	291	3	287	4.0e-19	88.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
648931097	421	29.49	13	379	1	366	8.0e-63	234	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648931098	649	38.62	360	647	11	297	2.0e-64	240	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
648931099	378	29.84	4	375	1	314	2.0e-34	139	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
648931100	249	60.57	4	249	2	246	4.0e-91	327	COG4674	ABC-type uncharacterized transport system, ATPase component	249
648931101	232	46.58	1	217	3	220	6.0e-74	270	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
648931102	272	34.2	10	270	3	269	1.0e-49	190	COG0829	Urease accessory protein UreH	269
648931103	100	65	1	100	1	100	4.0e-41	159	COG0831	Urease gamma subunit	100
648931105	101	67.33	1	101	1	101	4.0e-42	162	COG0832	Urease beta subunit	106
648931106	569	75.7	2	569	1	568	0.0e+00	1032	COG0804	Urease alpha subunit	568
648931107	149	47.06	14	149	19	153	3.0e-31	128	COG2371	Urease accessory protein UreE	155
648931108	207	37.84	6	207	8	229	2.0e-43	169	COG0830	Urease accessory protein UreF	229
648931109	200	50.75	1	200	10	202	3.0e-58	218	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
648931110	306	32.01	6	306	2	297	1.0e-33	137	COG0583	DNA-binding transcriptional regulator, LysR family	297
648931113	454	24.76	147	453	23	329	4.0e-33	136	COG0642	Signal transduction histidine kinase	336
648931114	223	40.87	1	222	1	229	3.0e-46	178	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648931115	368	22.88	6	320	1	280	4.0e-08	53	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
648931118	675	31.91	11	500	7	486	8.0e-77	282	COG3333	TctA family transporter	504
648931119	361	42.63	1	359	1	377	8.0e-94	337	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
648931120	323	36.11	1	321	2	318	1.0e-64	240	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
648931121	599	30.22	158	591	1	443	1.0e-88	321	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
648931122	580	35.49	1	577	3	605	3.0e-119	422	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
648931123	316	32.52	1	282	1	286	2.0e-51	196	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
648931124	479	46.07	9	473	2	464	0.0e+00	467	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648931125	402	34.26	1	390	4	372	2.0e-72	266	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
648931126	550	43.04	3	544	5	542	4.0e-114	405	COG2303	Choline dehydrogenase or related flavoprotein	542
648931128	293	24.83	5	290	1	290	2.0e-30	126	COG0583	DNA-binding transcriptional regulator, LysR family	297
648931130	324	35.19	1	322	1	321	2.0e-71	262	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
648931131	479	19.96	24	473	2	430	1.0e-25	111	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648931132	288	36.24	1	285	10	295	4.0e-52	198	COG1175	ABC-type sugar transport system, permease component	295
648931133	285	36.49	4	284	6	281	5.0e-48	184	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648931134	368	42.24	1	348	1	336	9.0e-94	337	COG3839	ABC-type sugar transport system, ATPase component	338
648931135	373	39.5	1	361	1	338	2.0e-92	333	COG3839	ABC-type sugar transport system, ATPase component	338
648931136	520	31.38	4	509	3	498	2.0e-87	316	COG1070	Sugar (pentulose or hexulose) kinase	502
648931137	346	37.5	35	346	9	315	5.0e-74	271	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
648931138	527	46.67	17	506	8	493	0.0e+00	502	COG0578	Glycerol-3-phosphate dehydrogenase	532
648931139	355	25.9	13	348	17	404	5.0e-39	155	COG3347	Rhamnose utilisation protein RhaD, predicted bifunctional aldolase and dehydrogenase	404
648931140	419	24.5	1	414	1	448	1.0e-51	197	COG1070	Sugar (pentulose or hexulose) kinase	502
648931141	272	31.09	8	270	1	258	7.0e-42	164	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
648931142	218	35.75	1	216	1	219	2.0e-46	178	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
648931143	477	53.18	1	476	1	463	0.0e+00	556	COG1282	NAD/NADP transhydrogenase beta subunit	463
648931144	525	51.22	4	372	1	356	5.0e-112	398	COG3288	NAD/NADP transhydrogenase alpha subunit	356
648931145	413	52.99	26	410	1	358	2.0e-121	429	COG1312	D-mannonate dehydratase	362
648931146	476	41.6	2	474	1	472	1.0e-123	437	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
648931147	468	46.65	4	466	1	461	0.0e+00	529	COG1904	Glucuronate isomerase	463
648931149	508	44.38	89	247	1	157	2.0e-28	120	COG3436	Transposase	157
648931152	342	41.75	28	333	3	302	3.0e-83	302	COG1004	UDP-glucose 6-dehydrogenase	414
648931159	492	42.24	1	464	5	450	2.0e-128	453	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
648931160	1168	37.94	645	896	94	334	7.0e-43	169	COG0642	Signal transduction histidine kinase	336
648931162	502	34.24	3	436	1	425	4.0e-63	235	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
648931167	488	15.13	8	427	1	388	2.0e-06	48	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
648931169	205	29.63	53	187	10	134	6.0e-13	67.7	COG3415	Transposase	138
648931175	283	39.76	29	272	3	256	2.0e-59	222	COG3622	Hydroxypyruvate isomerase	260
648931176	299	37.46	8	299	4	305	4.0e-61	228	COG3386	Sugar lactone lactonase YvrE	307
648931177	139	38.69	6	137	4	140	5.0e-17	80.3	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
648931178	343	36.54	1	342	1	350	2.0e-72	266	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
648931179	315	37.5	3	314	2	321	1.0e-80	293	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
648931180	257	37.4	8	254	1	251	4.0e-44	171	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648931181	162	49.69	3	158	1	158	3.0e-52	197	COG3265	Gluconate kinase	161
648931182	296	40.91	3	287	1	286	3.0e-68	252	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
648931184	312	36.83	1	311	2	281	8.0e-50	191	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648931185	303	40.68	1	292	2	294	1.0e-61	229	COG1175	ABC-type sugar transport system, permease component	295
648931186	442	26.73	1	435	1	432	5.0e-33	135	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648931187	360	49.58	1	355	1	338	3.0e-113	401	COG3839	ABC-type sugar transport system, ATPase component	338
648931188	342	34.74	12	338	3	330	3.0e-66	245	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
648931189	338	32.63	5	334	1	329	6.0e-73	267	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
648931190	375	24.46	51	369	24	335	7.0e-27	115	COG0642	Signal transduction histidine kinase	336
648931191	256	43.11	25	245	2	225	5.0e-55	207	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648931195	289	22.04	34	273	34	261	2.0e-13	70.2	COG1082	Sugar phosphate isomerase/epimerase	274
648931196	304	36.33	1	266	1	265	1.0e-51	196	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
648931197	245	34.89	6	238	4	238	7.0e-40	157	COG2186	DNA-binding transcriptional regulator, FadR family	241
648931198	371	33.51	1	358	3	364	9.0e-64	237	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
648931199	344	36.13	5	337	4	348	5.0e-63	235	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
648931200	256	38.34	7	253	1	250	6.0e-45	174	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648931203	388	35.31	1	387	1	368	6.0e-68	251	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
648931204	281	21.26	102	274	10	181	8.0e-15	74.5	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
648931206	315	22.44	4	256	13	233	1.0e-09	57.7	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
648931207	502	49.12	104	502	6	381	0.0e+00	467	COG2721	Altronate dehydratase	381
648931208	361	26.33	6	351	3	342	2.0e-38	153	COG0673	Predicted dehydrogenase	342
648931209	300	32.5	5	283	2	279	5.0e-52	198	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
648931212	593	37.52	8	564	1	529	0.0e+00	463	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
648931213	469	17.88	3	443	28	469	3.0e-29	123	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648931214	292	22.58	15	275	6	270	8.0e-15	74.5	COG1082	Sugar phosphate isomerase/epimerase	274
648931215	395	24.54	20	395	1	340	2.0e-40	160	COG0673	Predicted dehydrogenase	342
648931217	383	27.37	1	365	1	341	1.0e-46	181	COG0673	Predicted dehydrogenase	342
648931219	628	38.52	266	628	2	360	2.0e-93	336	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
648931220	431	47.59	55	428	7	379	5.0e-86	311	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648931221	186	25.56	1	180	5	174	4.0e-16	78.1	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648931222	337	33.73	7	337	1	332	3.0e-51	195	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648931223	364	26.48	4	346	3	341	7.0e-45	174	COG0673	Predicted dehydrogenase	342
648931225	218	30.77	1	218	10	223	2.0e-29	122	COG1802	DNA-binding transcriptional regulator, GntR family	230
648931234	453	28.15	22	289	7	257	3.0e-17	83.2	COG4584	Transposase	278
648931237	151	24.16	3	151	1	146	2.0e-09	55	COG3499	Phage protein U	147
648931238	68	44.26	4	63	5	65	4.0e-10	56.5	COG5004	P2-like prophage tail protein X	70
648931239	328	23.92	1	327	5	341	3.0e-21	95.8	COG3500	Phage protein D	350
648931256	345	23.61	39	323	7	283	9.0e-21	94.6	COG2842	Bacteriophage DNA transposition protein, AAA+ family ATPase	297
648931268	401	28.89	216	342	37	171	1.0e-07	51.6	COG3409	Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases	185
648931275	503	36.22	1	488	17	505	2.0e-108	386	COG4373	Mu-like prophage FluMu protein gp28	509
648931276	550	29.61	20	542	14	511	6.0e-75	275	COG4383	Mu-like prophage protein gp29	517
648931280	330	22.35	16	313	9	357	3.0e-14	72.8	COG4388	Mu-like prophage I protein	357
648931286	154	32.79	3	123	2	116	4.0e-12	64.2	COG4387	Mu-like prophage protein gp36	139
648931291	283	33.22	1	280	7	303	1.0e-29	123	COG3948	Phage-related baseplate assembly protein	306
648931297	410	22.05	7	376	15	376	9.0e-16	78.4	COG3497	Phage tail sheath protein FI	394
648931298	168	22.29	8	166	10	167	2.0e-07	48.4	COG3498	Phage tail tube protein FII	169
648931304	337	24.42	5	332	6	339	6.0e-28	118	COG3500	Phage protein D	350
648931305	269	25.87	34	262	18	265	7.0e-31	127	COG0863	DNA modification methylase	302
648931310	390	43.75	11	373	1	356	5.0e-123	434	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
648931312	219	28.77	2	210	7	216	2.0e-23	102	COG1843	Flagellar hook assembly protein FlgD	222
648931314	537	35.06	1	535	9	544	4.0e-104	372	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
648931315	349	39.16	20	348	10	339	4.0e-69	255	COG1536	Flagellar motor switch protein FliG	339
648931317	112	40.95	3	107	32	136	3.0e-18	83.9	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
648931318	451	43.01	1	445	5	464	9.0e-114	404	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
648931319	721	49.57	27	721	4	693	0.0e+00	813	COG1298	Flagellar biosynthesis pathway, component FlhA	696
648931323	306	23.59	2	296	1	260	5.0e-29	121	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
648931325	135	30.97	3	111	11	121	2.0e-11	61.6	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
648931326	324	65.14	1	321	1	324	0.0e+00	502	COG0435	Glutathionyl-hydroquinone reductase	324
648931327	166	36.94	8	160	6	162	7.0e-32	130	COG3153	Predicted N-acetyltransferase YhbS	171
648931332	336	40.9	11	336	1	326	1.0e-63	237	COG0714	MoxR-like ATPase	329
648931333	206	56.15	18	200	14	200	2.0e-58	218	COG3816	Uncharacterized protein	205
648931336	416	28.26	15	411	5	402	4.0e-54	205	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
648931337	375	29.44	116	361	75	322	1.0e-44	173	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
648931339	304	50.52	17	297	3	268	7.0e-112	396	COG0408	Coproporphyrinogen III oxidase	303
648931340	159	43.33	1	149	2	150	2.0e-46	178	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
648931341	612	33.39	28	608	4	567	2.0e-109	390	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
648931342	136	43.18	3	134	2	132	6.0e-26	110	COG4852	Uncharacterized membrane protein	134
648931343	439	24.94	52	436	46	403	4.0e-22	99.7	COG0840	Methyl-accepting chemotaxis protein	408
648931346	612	31.51	21	604	1	567	6.0e-108	385	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
648931348	186	36.7	1	186	1	166	3.0e-36	144	COG0723	Rieske Fe-S protein	177
648931349	421	53.8	16	381	10	371	7.0e-100	357	COG1290	Cytochrome b subunit of the bc complex	381
648931350	277	39.21	2	276	1	250	8.0e-59	220	COG2857	Cytochrome c1	250
648931351	292	37.25	6	247	19	262	1.0e-63	236	COG0005	Purine nucleoside phosphorylase	262
648931352	182	48.31	4	181	2	179	2.0e-47	182	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
648931353	215	26.67	13	200	2	196	6.0e-20	90.8	COG0778	Nitroreductase	207
648931355	163	27.04	3	158	15	158	3.0e-22	97.9	COG2030	Acyl dehydratase	159
648931356	173	33.77	21	171	10	159	8.0e-24	103	COG2030	Acyl dehydratase	159
648931357	288	34.21	138	288	3	154	2.0e-23	103	COG3449	DNA gyrase inhibitor GyrI	154
648931359	328	37.01	1	327	1	325	1.0e-57	217	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
648931360	227	41.94	14	227	49	263	5.0e-61	227	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
648931361	366	58.98	1	366	1	372	0.0e+00	484	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
648931363	342	31.15	104	342	35	249	2.0e-34	139	COG3719	Ribonuclease I	249
648931364	346	27.94	75	346	5	249	3.0e-30	125	COG3719	Ribonuclease I	249
648931365	241	50.27	1	184	2	186	4.0e-67	248	COG0193	Peptidyl-tRNA hydrolase	190
648931366	207	43.62	4	97	1	93	1.0e-22	99	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
648931368	229	37.98	7	214	2	206	6.0e-52	197	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
648931369	337	60	28	336	5	313	2.0e-120	426	COG0462	Phosphoribosylpyrophosphate synthetase	314
648931371	385	33.51	1	383	1	383	2.0e-69	256	COG0006	Xaa-Pro aminopeptidase	384
648931372	255	43.27	8	252	10	247	7.0e-70	257	COG1496	Copper oxidase (laccase) domain	249
648931373	366	43.75	2	359	1	366	3.0e-94	339	COG1565	SAM-dependent methyltransferase, MidA family	370
648931374	257	42.61	5	218	2	223	6.0e-49	187	COG0682	Prolipoprotein diacylglyceryltransferase	287
648931375	82	51.25	1	80	9	88	4.0e-14	69.7	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
648931376	166	59.04	1	166	1	166	4.0e-55	207	COG5465	Uncharacterized protein	166
648931377	273	43.66	8	273	3	266	4.0e-60	225	COG0345	Pyrroline-5-carboxylate reductase	266
648931379	113	33.9	1	112	7	123	2.0e-15	74.2	COG0073	tRNA-binding EMAP/Myf domain	123
648931380	444	27.11	129	443	2	328	4.0e-34	139	COG0642	Signal transduction histidine kinase	336
648931381	232	41.59	12	230	2	226	2.0e-55	209	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648931382	194	28.87	55	151	15	111	9.0e-13	66.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
648931384	300	39.58	10	289	1	281	9.0e-68	250	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
648931385	437	18.9	58	421	31	380	1.0e-14	74.5	COG2814	Predicted arabinose efflux permease, MFS family	394
648931386	155	42.67	4	151	3	149	2.0e-40	158	COG0314	Molybdopterin synthase catalytic subunit	149
648931387	83	38.27	3	83	4	84	3.0e-17	80	COG1977	Molybdopterin converting factor, small subunit	84
648931388	190	41.15	1	190	6	191	8.0e-24	103	COG0558	Phosphatidylglycerophosphate synthase	192
648931389	96	37.63	5	95	3	95	2.0e-17	80.4	COG5453	Uncharacterized protein	96
648931390	213	44.39	1	186	3	189	3.0e-66	244	COG1435	Thymidine kinase	201
648931391	342	21.38	102	337	1	259	6.0e-11	62.2	COG0708	Exonuclease III	261
648931394	659	48.02	27	656	1	581	0.0e+00	666	COG0322	Excinuclease UvrABC, nuclease subunit	581
648931395	255	29.64	1	241	1	250	8.0e-31	127	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648931396	330	37.12	1	325	8	320	1.0e-35	143	COG0530	Ca2+/Na+ antiporter	320
648931397	242	32.03	19	242	1	199	8.0e-20	90.8	COG3637	Opacity protein and related surface antigens	199
648931399	1059	24.35	11	1035	1	1009	0.0e+00	478	COG0841	Multidrug efflux pump subunit AcrB	1009
648931400	215	30.61	2	192	1	194	1.0e-21	96.8	COG0625	Glutathione S-transferase	211
648931402	282	50	1	282	1	279	8.0e-93	333	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
648931403	171	34.55	1	162	1	162	1.0e-21	95.8	COG3818	Predicted acetyltransferase, GNAT superfamily	167
648931405	289	55.22	210	276	1	65	2.0e-16	80.2	COG1278	Cold shock protein, CspA family	67
648931408	229	32.09	21	228	12	226	4.0e-33	134	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648931412	436	21.99	20	424	9	431	8.0e-28	118	COG2211	Na+/melibiose symporter or related transporter	467
648931415	101	39.39	2	100	9	107	9.0e-22	95	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
648931419	713	67.59	232	700	1	469	0.0e+00	836	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
648931421	221	27.15	53	197	31	177	9.0e-10	57.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
648931425	291	22.79	35	290	1	264	3.0e-11	62.7	COG0510	Thiamine kinase and related kinases	269
648931426	311	34.42	4	305	14	319	2.0e-42	166	COG3503	Uncharacterized membrane protein	323
648931434	399	44.33	6	399	1	393	2.0e-115	409	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
648931436	521	31.83	82	495	8	416	3.0e-69	256	COG1574	Predicted amidohydrolase YtcJ	535
648931438	153	35.29	29	128	12	113	2.0e-16	78.4	COG3439	Uncharacterized conserved protein, DUF302 family	137
648931439	321	35.44	22	296	1	271	9.0e-53	200	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
648931443	298	32.11	1	295	1	293	7.0e-41	161	COG0583	DNA-binding transcriptional regulator, LysR family	297
648931444	322	57.88	4	313	2	304	9.0e-95	340	COG0492	Thioredoxin reductase	305
648931445	324	31.58	5	311	2	322	5.0e-46	178	COG3660	Mitochondrial fission protein ELM1	329
648931446	156	38.96	1	154	2	154	5.0e-31	127	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648931448	157	52.98	6	156	1	150	7.0e-39	153	COG0782	Transcription elongation factor, GreA/GreB family	151
648931449	1120	67.15	13	426	1	393	0.0e+00	559	COG0458	Carbamoylphosphate synthase large subunit	400
648931452	140	31.09	23	139	3	112	3.0e-16	77.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
648931453	422	54.07	42	422	3	368	0.0e+00	527	COG0505	Carbamoylphosphate synthase small subunit	368
648931454	163	37.16	1	148	3	147	7.0e-28	116	COG1610	Uncharacterized conserved protein YqeY	148
648931455	654	35.38	2	534	1	517	3.0e-106	379	COG0358	DNA primase (bacterial type)	568
648931457	669	49.03	312	668	1	342	2.0e-99	357	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
648931463	103	33.33	1	93	10	100	6.0e-09	52.5	COG0640	DNA-binding transcriptional regulator, ArsR family	110
648931464	353	25.4	47	353	9	316	7.0e-27	114	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
648931465	365	22.05	1	364	5	379	9.0e-25	108	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648931466	169	30	6	162	5	177	2.0e-22	98.8	COG3038	Cytochrome b561	181
648931467	290	43.37	7	285	6	282	2.0e-75	276	COG0421	Spermidine synthase	282
648931468	172	46.02	63	172	15	127	1.0e-31	129	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
648931470	260	44.86	19	257	3	241	4.0e-50	191	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
648931471	355	27.01	1	341	9	351	1.0e-25	110	COG0628	Predicted PurR-regulated permease PerM	355
648931476	250	43.22	18	216	4	194	2.0e-42	166	COG3316	Transposase (or an inactivated derivative)	215
648931477	426	22	64	361	48	301	7.0e-08	52.3	COG1566	Multidrug resistance efflux pump	352
648931482	325	37.46	1	319	1	314	1.0e-61	230	COG2826	Transposase and inactivated derivatives, IS30 family	318
648931484	250	43.22	18	216	4	194	2.0e-42	166	COG3316	Transposase (or an inactivated derivative)	215
648931487	234	29.83	36	199	12	190	8.0e-18	84.2	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
648931493	257	43.88	4	238	3	238	5.0e-62	231	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
648931494	377	41.49	45	376	3	334	2.0e-53	203	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
648931495	383	22	10	354	14	319	4.0e-32	132	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
648931513	110	31.4	20	100	18	98	7.0e-10	55.7	COG5489	Uncharacterized conserved protein, DUF736 family	107
648931517	192	38.46	4	187	3	197	1.0e-28	119	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
648931518	991	37.92	624	950	1	323	7.0e-93	335	COG4644	Transposase and inactivated derivatives, TnpA family	323
648931527	604	28.04	313	581	1	264	8.0e-35	142	COG4644	Transposase and inactivated derivatives, TnpA family	323
648931530	211	28.02	11	210	2	207	1.0e-16	79.8	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
648931535	150	53.44	1	131	5	135	9.0e-45	172	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
648931539	259	49.73	9	192	6	190	5.0e-54	204	COG4669	Type III secretory pathway, lipoprotein EscJ	246
648931542	455	47.17	17	455	5	440	0.0e+00	495	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
648931544	348	26.32	233	343	23	136	2.0e-08	53.5	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
648931545	212	42.92	1	211	1	212	2.0e-48	185	COG4790	Type III secretory pathway, component EscR	214
648931549	684	42.5	14	682	5	687	0.0e+00	602	COG4789	Type III secretory pathway, component EscV	689
648931550	411	29.34	15	401	27	414	7.0e-52	198	COG4964	Flp pilus assembly protein, secretin CpaC	455
648931565	280	27.54	22	253	11	242	4.0e-18	85.7	COG4791	Type III secretory pathway, component EscT	259
648931569	132	21.74	19	126	1	112	2.0e-09	54.7	COG3293	Transposase	124
648931575	973	20.36	38	360	7	224	1.0e-07	52.9	COG0796	Glutamate racemase	269
648931578	329	25.82	1	327	10	342	2.0e-21	97	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648931580	348	27.78	15	337	1	322	4.0e-56	212	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
648931581	506	46.78	21	499	1	471	0.0e+00	496	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648931582	255	36.58	1	252	4	257	1.0e-42	166	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648931583	524	47.83	1	524	1	519	0.0e+00	635	COG4670	Acyl CoA:acetate/3-ketoacid CoA transferase	527
648931584	333	33.83	1	328	4	340	1.0e-47	183	COG0673	Predicted dehydrogenase	342
648931587	383	22.87	9	381	2	340	2.0e-47	183	COG0673	Predicted dehydrogenase	342
648931588	240	22.27	11	204	3	203	9.0e-11	60.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648931589	266	38.91	6	258	3	248	2.0e-52	199	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
648931591	390	21.57	2	366	10	399	1.0e-08	54.8	COG0738	Fucose permease	422
648931592	447	30.93	1	424	2	413	1.0e-68	254	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
648931594	277	48.79	24	271	1	244	2.0e-81	295	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
648931595	173	37.5	20	138	7	126	7.0e-12	63.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
648931596	152	44.09	26	147	44	168	1.0e-29	122	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
648931598	367	40.24	27	358	2	333	8.0e-80	290	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
648931599	723	39.23	534	713	1	181	1.0e-40	161	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
648931600	339	37.15	23	333	3	324	4.0e-80	292	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
648931601	392	43.56	10	388	5	390	4.0e-99	355	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
648931602	349	45.29	12	346	1	320	5.0e-96	344	COG0523	GTPase, G3E family	323
648931605	530	34.74	3	529	11	538	4.0e-111	395	COG0405	Gamma-glutamyltranspeptidase	539
648931606	303	28.23	7	295	6	294	4.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
648931612	329	32.51	5	326	46	401	3.0e-68	252	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
648931614	616	39.09	306	612	20	300	7.0e-65	242	COG2215	ABC-type nickel/cobalt efflux system, permease component RcnA	303
648931615	252	42.63	1	247	1	243	7.0e-72	264	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
648931616	216	42.86	7	214	1	210	2.0e-52	199	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
648931617	455	41.78	1	445	1	447	2.0e-112	399	COG4564	Signal transduction histidine kinase	459
648931618	366	43.33	1	356	1	359	7.0e-88	317	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
648931620	888	38.52	8	556	10	446	5.0e-102	366	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
648931621	249	42.22	23	242	5	225	4.0e-48	184	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648931622	655	26.34	259	515	95	336	2.0e-28	121	COG0642	Signal transduction histidine kinase	336
648931623	661	34.48	13	620	16	611	7.0e-125	441	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
648931624	273	46.83	20	271	2	250	5.0e-84	304	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
648931625	317	29.87	15	316	1	297	1.0e-35	144	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
648931626	358	27.55	29	350	8	314	8.0e-36	144	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
648931627	443	18.23	27	407	5	362	8.0e-15	75.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648931628	285	53.28	20	263	1	237	2.0e-79	288	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
648931629	411	31.18	2	409	14	436	1.0e-59	224	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
648931630	372	47.42	42	370	1	320	9.0e-109	387	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
648931631	332	41.67	8	300	2	291	4.0e-56	212	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
648931632	157	40.85	8	148	2	140	5.0e-24	103	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
648931633	284	26.62	1	274	2	243	9.0e-32	130	COG1360	Flagellar motor protein MotB	244
648931634	255	37.6	1	254	1	257	4.0e-50	191	COG1291	Flagellar motor component MotA	266
648931635	337	55.17	21	222	2	201	2.0e-60	226	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
648931637	488	29.78	48	487	26	467	2.0e-54	207	COG5338	Uncharacterized protein	468
648931638	415	45.68	23	344	21	342	2.0e-95	343	COG2951	Membrane-bound lytic murein transglycosylase B	343
648931639	382	31.13	54	350	58	354	3.0e-38	152	COG2845	Uncharacterized protein	354
648931640	476	44.35	22	468	1	450	0.0e+00	484	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
648931641	1575	60.2	743	1239	1	485	0.0e+00	665	COG0069	Glutamate synthase domain 2	485
648931642	106	49.45	1	89	11	101	3.0e-16	76.8	COG5572	Uncharacterized membrane protein	104
648931643	295	43.22	14	284	3	271	2.0e-78	286	COG3220	Uncharacterized conserved protein, UPF0276 family	282
648931646	362	40.79	12	361	1	338	2.0e-96	345	COG2008	Threonine aldolase	342
648931647	149	38.57	1	136	7	145	3.0e-28	117	COG0071	Molecular chaperone IbpA, HSP20 family	146
648931649	348	27.54	7	348	1	296	4.0e-44	172	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
648931650	263	34.25	9	258	6	259	5.0e-56	211	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
648931652	295	43.68	8	284	2	264	2.0e-75	276	COG3741	N-formylglutamate amidohydrolase	272
648931658	327	25.7	40	316	2	282	3.0e-16	79.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648931659	372	50.68	1	364	109	477	4.0e-123	435	COG0469	Pyruvate kinase	477
648931661	173	49.64	30	163	7	143	3.0e-36	144	COG5480	Uncharacterized membrane protein	147
648931663	269	50.39	15	267	11	262	1.0e-83	303	COG3931	Predicted N-formylglutamate amidohydrolase	263
648931664	101	70.71	1	99	3	101	4.0e-36	142	COG3492	Uncharacterized protein	104
648931665	85	68.75	1	80	5	84	5.0e-23	99.2	COG3750	Uncharacterized conserved protein, UPF0335 family	85
648931666	612	52.87	5	177	14	185	9.0e-56	211	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
648931667	558	42.8	33	553	2	460	0.0e+00	497	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
648931668	590	37.9	1	590	7	597	0.0e+00	535	COG1164	Oligoendopeptidase F	598
648931670	457	29.75	16	447	27	449	5.0e-77	282	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
648931672	223	40.53	4	223	63	289	3.0e-53	201	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
648931676	471	32.31	14	467	10	455	7.0e-60	225	COG0534	Na+-driven multidrug efflux pump	455
648931677	365	51.26	12	365	3	354	2.0e-124	439	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
648931678	162	62.18	4	159	3	156	8.0e-58	216	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
648931679	68	58.33	9	68	9	67	9.0e-10	55.4	COG5481	Uncharacterized protein	67
648931681	59	48.21	1	56	1	56	8.0e-07	45.4	COG5570	Uncharacterized protein	57
648931682	549	33.21	27	548	11	527	6.0e-108	384	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648931683	254	22.18	6	252	3	258	2.0e-07	49.6	COG0730	Uncharacterized membrane protein YfcA	258
648931685	637	38.5	46	606	1	522	0.0e+00	563	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
648931686	263	42.86	1	251	1	251	4.0e-50	191	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648931687	596	41.84	13	588	1	567	0.0e+00	464	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
648931691	74	41.33	1	73	1	72	1.0e-17	81.1	COG0254	Ribosomal protein L31	75
648931692	181	55.49	15	178	12	173	3.0e-46	178	COG5317	Uncharacterized protein	175
648931695	333	43.94	8	332	1	326	2.0e-78	285	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
648931696	238	64.53	1	233	1	222	9.0e-78	283	COG3820	Uncharacterized protein	230
648931697	344	30.23	131	344	31	243	4.0e-38	152	COG1360	Flagellar motor protein MotB	244
648931699	279	45.77	17	274	1	260	2.0e-70	259	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
648931700	187	43.08	1	130	2	131	4.0e-37	147	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
648931701	371	32.72	108	318	32	248	6.0e-24	105	COG0790	TPR repeat	292
648931702	213	27.75	1	206	3	209	2.0e-25	109	COG0352	Thiamine monophosphate synthase	211
648931703	355	43.33	1	329	1	286	2.0e-95	342	COG0191	Fructose/tagatose bisphosphate aldolase	286
648931705	397	53.37	1	397	1	392	0.0e+00	491	COG0126	3-phosphoglycerate kinase	395
648931706	229	33.17	22	225	2	208	5.0e-24	104	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
648931707	336	61.38	2	334	1	332	0.0e+00	466	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
648931708	661	55.31	2	660	1	662	0.0e+00	941	COG0021	Transketolase	663
648931712	123	26.85	1	108	1	105	2.0e-14	71.1	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
648931713	196	37.43	12	192	5	190	1.0e-34	139	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
648931714	275	56.02	1	265	1	262	2.0e-103	368	COG1692	Calcineurin-like phosphoesterase	266
648931715	248	62.24	1	240	1	241	1.0e-98	352	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
648931719	205	42.86	1	203	1	200	4.0e-54	204	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
648931721	346	64.76	4	333	1	332	0.0e+00	506	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
648931722	152	38.97	11	145	1	131	2.0e-27	114	COG0824	Acyl-CoA thioesterase FadM	137
648931724	150	45.93	15	149	3	137	5.0e-39	153	COG0848	Biopolymer transport protein ExbD	137
648931726	449	40.14	20	447	1	424	1.0e-104	374	COG0823	Periplasmic component of the Tol biopolymer transport system	425
648931729	308	28.42	20	304	39	262	2.0e-31	129	COG1729	Periplasmic TolA-binding protein (function unknown)	262
648931730	446	33.76	37	268	24	255	2.0e-37	149	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
648931731	640	56.31	9	603	1	595	0.0e+00	758	COG0465	ATP-dependent Zn proteases	596
648931732	447	45.85	1	444	6	459	8.0e-120	424	COG1109	Phosphomannomutase	464
648931733	272	22.09	4	252	1	199	1.0e-19	90.5	COG3637	Opacity protein and related surface antigens	199
648931752	142	29.77	1	129	1	126	2.0e-13	68.5	COG3499	Phage protein U	147
648931756	344	20.99	9	329	8	338	3.0e-14	72.7	COG3500	Phage protein D	350
648931761	296	29.15	2	294	1	289	3.0e-34	139	COG0583	DNA-binding transcriptional regulator, LysR family	297
648931767	294	24.08	1	294	1	296	1.0e-26	114	COG0583	DNA-binding transcriptional regulator, LysR family	297
648931768	153	37.91	1	153	3	154	2.0e-32	131	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648931769	338	48.66	1	335	1	323	3.0e-105	375	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
648931772	392	34.27	10	385	2	365	1.0e-108	386	COG1932	Phosphoserine aminotransferase	365
648931773	528	47.4	1	325	2	324	8.0e-93	334	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
648931779	276	34.92	23	272	2	253	3.0e-42	165	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
648931780	313	34.15	1	312	4	323	4.0e-38	151	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
648931781	294	39.3	10	290	64	339	6.0e-66	244	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
648931782	341	47.47	16	329	2	289	6.0e-83	301	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
648931785	256	40.87	1	252	2	253	8.0e-66	243	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
648931787	196	62.36	19	196	32	205	2.0e-64	238	COG5400	Uncharacterized protein	205
648931789	214	54.29	1	209	3	209	3.0e-59	221	COG5385	Uncharacterized protein	214
648931791	158	31.45	1	158	4	162	9.0e-27	113	COG0835	Chemotaxis signal transduction protein	165
648931793	420	39.3	19	420	2	348	7.0e-79	287	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
648931794	290	37.08	3	268	1	264	1.0e-66	246	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
648931796	230	40	1	225	1	229	2.0e-56	212	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648931797	441	55.45	6	436	14	439	0.0e+00	554	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
648931802	761	19.35	41	728	131	819	6.0e-34	139	COG3264	Small-conductance mechanosensitive channel	835
648931803	507	47.05	4	501	12	515	0.0e+00	516	COG0578	Glycerol-3-phosphate dehydrogenase	532
648931804	499	61.43	9	498	7	495	0.0e+00	739	COG0554	Glycerol kinase	499
648931805	121	29.13	1	103	10	110	8.0e-10	56	COG0640	DNA-binding transcriptional regulator, ArsR family	110
648931806	162	36.81	1	139	2	136	9.0e-28	116	COG0394	Protein-tyrosine-phosphatase	139
648931807	225	26.05	4	217	2	239	8.0e-31	127	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
648931808	212	30	5	212	15	223	2.0e-26	112	COG1802	DNA-binding transcriptional regulator, GntR family	230
648931809	297	33.67	1	294	4	297	3.0e-61	228	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
648931810	413	28.5	1	413	2	381	5.0e-38	152	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648931811	347	51.19	1	335	2	337	2.0e-122	432	COG3938	Proline racemase	341
648931816	810	58.63	25	807	9	779	0.0e+00	949	COG2183	Transcriptional accessory protein Tex/SPT6	780
648931819	303	30.85	12	293	1	293	3.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
648931820	144	31.78	1	128	1	129	3.0e-21	94.3	COG3791	Uncharacterized conserved protein	133
648931823	455	25.63	61	451	1	381	6.0e-55	208	COG0006	Xaa-Pro aminopeptidase	384
648931824	811	34.75	418	811	1	379	5.0e-94	339	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
648931825	523	49.33	1	522	5	526	0.0e+00	600	COG5598	Trimethylamine:corrinoid methyltransferase	526
648931826	481	52.25	13	477	4	467	0.0e+00	604	COG0362	6-phosphogluconate dehydrogenase	473
648931828	238	28.31	1	212	10	220	1.0e-17	83.4	COG0785	Cytochrome c biogenesis protein CcdA	220
648931832	320	37.11	39	320	34	324	3.0e-61	229	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
648931833	137	55.88	1	136	2	137	7.0e-50	189	COG3565	Predicted dioxygenase of extradiol dioxygenase family	138
648931834	290	25.85	1	285	1	291	8.0e-27	114	COG0583	DNA-binding transcriptional regulator, LysR family	297
648931848	222	20.35	1	192	1	231	2.0e-15	76	COG1192	Cellulose biosynthesis protein BcsQ	259
648931854	383	27.2	1	337	5	339	5.0e-36	145	COG3500	Phage protein D	350
648931856	130	37.1	8	130	1	124	3.0e-21	93.9	COG3499	Phage protein U	147
648931860	167	31.18	1	167	1	169	5.0e-22	97.3	COG3498	Phage tail tube protein FII	169
648931861	383	41.79	1	382	1	390	3.0e-86	312	COG3497	Phage tail sheath protein FI	394
648931865	253	39.1	105	251	5	150	5.0e-26	111	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
648931868	276	26.12	5	273	17	301	2.0e-15	76.6	COG3948	Phage-related baseplate assembly protein	306
648931869	129	38.46	1	104	3	105	5.0e-18	83.5	COG3628	Phage baseplate assembly protein W	116
648931870	202	31.35	18	202	2	184	1.0e-24	106	COG4540	Phage P2 baseplate assembly protein gpV	184
648931875	428	27.55	24	287	11	269	1.0e-28	120	COG0616	Periplasmic serine protease, ClpP class	317
648931876	465	26.78	11	456	18	456	6.0e-50	192	COG5511	Bacteriophage capsid protein	492
648931878	627	32.11	21	576	19	567	6.0e-94	338	COG5525	Phage terminase, large subunit GpA	611
648931879	275	29.57	17	258	4	257	1.0e-27	117	COG0338	Site-specific DNA-adenine methylase	274
648931884	392	23.05	130	374	22	282	1.0e-07	51.4	COG4974	Site-specific recombinase XerD	300
648931885	102	49.49	3	101	2	100	8.0e-24	101	COG3636	DNA-binding prophage protein	100
648931886	98	57.14	1	98	3	100	7.0e-31	125	COG3657	Putative component of the toxin-antitoxin plasmid stabilization module	100
648931902	514	48.11	6	508	5	502	0.0e+00	627	COG3046	Uncharacterized protein related to deoxyribodipyrimidine photolyase	505
648931910	195	42.41	3	193	4	194	2.0e-46	178	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
648931911	368	27.08	8	326	33	330	2.0e-38	153	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
648931912	468	24.05	13	377	8	332	4.0e-36	146	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
648931913	360	29.49	61	355	10	251	2.0e-39	156	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
648931914	550	48.82	1	254	1	243	1.0e-78	287	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
648931915	823	58.68	4	803	1	784	0.0e+00	1171	COG1251	NAD(P)H-nitrite reductase, large subunit	793
648931917	897	33.91	1	705	32	765	0.0e+00	473	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
648931918	477	50	216	453	2	235	3.0e-70	259	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
648931920	305	28.67	1	297	1	295	2.0e-41	162	COG0583	DNA-binding transcriptional regulator, LysR family	297
648931921	258	43.43	5	253	4	252	3.0e-79	288	COG1540	Lactam utilization protein B (function unknown)	252
648931924	291	32.11	5	250	1	219	9.0e-53	200	COG2049	Allophanate hydrolase subunit 1	223
648931925	334	41.38	14	330	1	307	3.0e-82	299	COG1984	Allophanate hydrolase subunit 2	314
648931926	358	26.62	56	343	30	319	1.0e-25	110	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
648931927	502	44.47	1	493	3	496	0.0e+00	524	COG1129	ABC-type sugar transport system, ATPase component	500
648931928	336	40.56	11	333	1	314	7.0e-48	184	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
648931929	428	51.62	1	422	16	446	0.0e+00	508	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
648931930	484	48.3	12	479	1	466	0.0e+00	527	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648931932	217	29.65	3	196	49	227	2.0e-25	109	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
648931933	203	22.94	1	196	2	212	1.0e-11	63.5	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
648931934	182	42.42	3	166	8	170	3.0e-21	95.2	COG1268	Biotin transporter BioY	184
648931936	315	17.83	169	297	1	122	3.0e-06	46.6	COG3335	Transposase	132
648931937	316	32.38	1	308	5	314	2.0e-59	222	COG1171	Threonine dehydratase	347
648931940	307	17.01	17	297	6	283	6.0e-09	55.2	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
648931941	286	46.01	13	286	10	285	1.0e-62	233	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648931942	326	39.31	1	308	1	312	4.0e-71	261	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648931943	286	33.73	18	268	1	248	2.0e-52	199	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
648931944	256	30.8	1	236	4	253	2.0e-49	189	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
648931945	522	29.45	1	513	4	546	6.0e-77	281	COG0747	ABC-type transport system, periplasmic component	556
648931946	329	50.15	16	329	25	348	6.0e-101	361	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
648931947	715	38.66	13	714	14	654	0.0e+00	657	COG0209	Ribonucleotide reductase alpha subunit	696
648931948	134	61.36	1	132	1	132	2.0e-45	174	COG1780	Protein involved in ribonucleotide reduction	141
648931949	73	33.77	1	73	1	77	6.0e-12	62.3	COG0695	Glutaredoxin	80
648931953	265	21.03	24	251	4	221	3.0e-09	56.1	COG2801	Transposase InsO and inactivated derivatives	232
648931955	501	27.51	8	494	2	469	7.0e-62	231	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648931956	332	39.09	1	329	2	328	5.0e-87	314	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
648931957	228	36.67	17	225	13	221	3.0e-28	119	COG1802	DNA-binding transcriptional regulator, GntR family	230
648931958	304	30.28	1	280	1	278	1.0e-36	146	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
648931959	390	35	39	390	22	370	2.0e-71	263	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
648931960	499	42.77	1	497	4	501	4.0e-124	438	COG3333	TctA family transporter	504
648931962	316	34.89	1	316	1	319	4.0e-48	185	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
648931963	280	45.49	3	267	2	267	7.0e-47	181	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
648931964	297	44.53	1	273	1	274	7.0e-49	187	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
648931965	302	51	12	260	5	252	3.0e-87	315	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
648931966	299	38.59	1	296	7	303	1.0e-78	286	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
648931967	771	40.33	366	660	1	299	3.0e-77	283	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
648931968	262	37.02	4	260	1	251	1.0e-38	153	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648931969	348	37.65	6	325	4	312	3.0e-56	212	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
648931970	330	30.42	11	328	10	336	6.0e-59	221	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
648931971	170	30.99	12	153	15	153	8.0e-26	109	COG2030	Acyl dehydratase	159
648931972	544	32.85	4	544	5	534	4.0e-116	412	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648931973	151	25.66	1	151	34	182	2.0e-14	72	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
648931974	307	29.1	7	299	1	296	7.0e-32	131	COG0583	DNA-binding transcriptional regulator, LysR family	297
648931975	405	37.02	29	405	5	393	3.0e-78	285	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648931976	393	27.76	3	381	2	381	2.0e-38	153	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648931977	289	31.91	4	258	11	266	7.0e-49	187	COG3741	N-formylglutamate amidohydrolase	272
648931978	362	37.96	12	360	40	383	3.0e-75	275	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
648931979	516	42.17	285	514	37	266	6.0e-70	258	COG2326	Polyphosphate kinase 2, PPK2 family	270
648931980	289	29.38	9	200	6	199	2.0e-25	109	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
648931986	296	21.03	9	254	10	250	4.0e-23	102	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648931987	136	50.39	1	128	1	129	2.0e-34	137	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
648931988	596	31.32	6	548	3	525	3.0e-93	336	COG0659	Sulfate permease or related transporter, MFS superfamily	554
648931993	164	66.9	10	151	9	150	2.0e-54	205	COG5321	Uncharacterized protein	164
648931994	527	29.79	10	473	2	461	4.0e-75	275	COG0415	Deoxyribodipyrimidine photolyase	461
648931995	51	71.79	2	40	5	43	5.0e-08	49.3	COG4338	Uncharacterized protein	54
648931996	483	41.38	1	481	5	497	5.0e-119	421	COG1070	Sugar (pentulose or hexulose) kinase	502
648931998	397	28.53	80	393	1	314	1.0e-34	141	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
648931999	451	34.58	19	449	1	450	4.0e-97	348	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
648932000	437	33.13	3	324	1	310	1.0e-81	297	COG0167	Dihydroorotate dehydrogenase	310
648932002	192	38.46	4	187	3	197	1.0e-28	119	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
648932003	991	37.92	624	950	1	323	7.0e-93	335	COG4644	Transposase and inactivated derivatives, TnpA family	323
648932005	152	42.86	4	150	1	146	1.0e-28	119	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648932008	467	37.99	1	453	10	465	6.0e-102	365	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648932009	410	47.91	4	406	3	409	1.0e-121	429	COG3799	Methylaspartate ammonia-lyase	410
648932010	375	40.05	4	373	6	380	2.0e-90	326	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
648932011	541	38.01	5	540	2	535	1.0e-108	387	COG2303	Choline dehydrogenase or related flavoprotein	542
648932012	284	35.44	6	281	1	282	2.0e-47	182	COG2301	Citrate lyase beta subunit	283
648932014	326	26.18	4	277	1	270	4.0e-43	168	COG4584	Transposase	278
648932016	140	34.78	1	138	3	131	9.0e-17	79.4	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
648932018	236	43.4	10	221	4	215	7.0e-47	180	COG3316	Transposase (or an inactivated derivative)	215
648932021	395	23.77	28	367	7	284	2.0e-19	90.3	COG0391	Archaeal 2-phospho-L-lactate transferase/Bacterial gluconeogenesis factor, CofD/UPF0052 family	323
648932023	500	22.79	98	496	43	450	9.0e-36	145	COG1538	Outer membrane protein TolC	457
648932028	730	26.79	32	725	15	697	1.0e-112	401	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
648932031	348	54.94	1	344	1	338	1.0e-124	439	COG3839	ABC-type sugar transport system, ATPase component	338
648932033	400	36.96	127	399	9	281	3.0e-48	186	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648932034	411	35.15	174	410	55	292	8.0e-48	184	COG1175	ABC-type sugar transport system, permease component	295
648932035	404	22.87	1	319	51	366	7.0e-20	92	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648932037	371	38.55	17	347	1	328	4.0e-68	252	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
648932041	265	21.03	24	251	4	221	2.0e-09	56.9	COG2801	Transposase InsO and inactivated derivatives	232
648932043	240	38.46	176	240	1	65	2.0e-12	66.5	COG2771	DNA-binding transcriptional regulator, CsgD family	65
648932056	469	37.8	27	468	8	458	3.0e-94	339	COG0277	FAD/FMN-containing dehydrogenase	459
648932057	164	28.68	15	143	11	137	7.0e-20	90.3	COG0824	Acyl-CoA thioesterase FadM	137
648932058	547	33.17	37	453	21	438	2.0e-63	237	COG0038	H+/Cl- antiporter ClcA	443
648932059	616	32.11	187	574	6	384	2.0e-58	220	COG0006	Xaa-Pro aminopeptidase	384
648932062	296	28.62	1	292	2	300	4.0e-51	195	COG2264	Ribosomal protein L11 methylase PrmA	300
648932063	441	27	121	441	1	330	1.0e-36	148	COG0642	Signal transduction histidine kinase	336
648932064	241	45.26	8	237	2	229	1.0e-51	196	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648932066	326	25.39	110	302	58	231	1.0e-11	64.2	COG2801	Transposase InsO and inactivated derivatives	232
648932067	801	45.23	42	677	1	648	0.0e+00	616	COG0210	Superfamily I DNA or RNA helicase	655
648932068	686	23.65	275	680	23	403	1.0e-24	108	COG0840	Methyl-accepting chemotaxis protein	408
648932069	721	52.55	17	720	1	667	0.0e+00	880	COG0272	NAD-dependent DNA ligase	667
648932070	556	46.24	1	555	1	556	0.0e+00	553	COG0497	DNA repair ATPase RecN	557
648932071	288	43.87	18	270	4	254	8.0e-67	247	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
648932072	312	51.35	7	300	3	298	3.0e-105	374	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
648932073	620	57.74	43	352	8	316	1.0e-105	377	COG0206	Cell division GTPase FtsZ	338
648932074	440	39.39	23	440	7	418	1.0e-113	403	COG0849	Cell division ATPase FtsA	418
648932075	304	26.88	41	289	15	266	1.0e-32	134	COG1589	Cell division septal protein FtsQ	269
648932076	309	38.2	3	306	1	317	2.0e-82	299	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
648932077	323	42.96	20	308	2	291	8.0e-90	323	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
648932078	471	51.07	1	465	1	459	0.0e+00	586	COG0773	UDP-N-acetylmuramate-alanine ligase	459
648932079	372	40.28	5	362	3	356	3.0e-88	318	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
648932080	385	36.68	6	371	2	378	4.0e-69	255	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
648932081	466	44.09	4	456	2	446	6.0e-117	414	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
648932082	361	46.99	19	361	1	316	3.0e-56	212	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
648932083	476	41.09	5	464	2	449	3.0e-112	399	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
648932084	489	39.32	21	485	10	474	1.0e-111	397	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
648932085	571	31.72	30	560	9	598	4.0e-99	355	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
648932087	346	53.38	18	323	6	314	9.0e-106	376	COG0275	16S rRNA C1402 N4-methylase RsmH	314
648932088	156	30.22	4	141	2	137	3.0e-22	98	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
648932091	495	24.77	1	419	5	425	8.0e-36	145	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
648932092	486	34.45	16	486	1	457	1.0e-91	330	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
648932093	235	26.67	28	192	2	164	1.0e-24	106	COG3467	Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily	166
648932094	265	37.31	1	263	2	251	4.0e-40	158	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648932095	513	34.28	1	510	11	529	3.0e-110	392	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648932096	503	20.41	5	297	3	291	3.0e-09	57	COG1344	Flagellin and related hook-associated protein FlgL	360
648932099	254	44.4	10	248	21	257	3.0e-71	261	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
648932100	230	24.86	55	224	1	173	5.0e-22	98.1	COG1076	DnaJ-domain-containing proteins 1	174
648932103	230	31.32	36	214	1	176	2.0e-37	149	COG0431	NAD(P)H-dependent FMN reductase	184
648932104	139	43.59	1	117	1	117	1.0e-37	148	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
648932105	116	32.32	1	99	10	106	2.0e-09	54.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
648932106	113	30.39	10	110	4	98	4.0e-08	49.9	COG2105	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family	120
648932107	179	42.31	1	179	18	199	3.0e-48	184	COG5631	Predicted transcription regulator, contains HTH domain, MarR family	199
648932108	1195	51.14	685	1194	1	522	0.0e+00	664	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
648932110	259	36.95	14	256	2	244	5.0e-44	171	COG0748	Putative heme iron utilization protein	245
648932113	208	39.9	1	205	1	208	8.0e-27	113	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
648932114	355	24.79	2	349	7	355	2.0e-19	90.4	COG5330	Uncharacterized conserved protein, DUF2336 family	364
648932115	202	41.15	6	193	2	193	9.0e-47	180	COG1182	FMN-dependent NADH-azoreductase	202
648932119	508	44.38	89	247	1	157	2.0e-28	120	COG3436	Transposase	157
648932120	1242	57.75	332	1201	3	842	0.0e+00	1126	COG1410	Methionine synthase I, cobalamin-binding domain	842
648932121	304	46.34	13	294	10	289	4.0e-78	284	COG0685	5,10-methylenetetrahydrofolate reductase	291
648932124	760	25	412	727	3	316	1.0e-33	138	COG0668	Small-conductance mechanosensitive channel	316
648932125	361	25.14	1	350	1	339	4.0e-18	85.8	COG5330	Uncharacterized conserved protein, DUF2336 family	364
648932126	202	37.37	2	190	8	193	6.0e-32	130	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
648932127	212	38.54	4	207	11	214	7.0e-45	173	COG2345	Predicted transcriptional regulator, ArsR family	218
648932129	107	50.55	1	91	15	105	6.0e-22	95.9	COG5586	Uncharacterized protein	110
648932136	550	46	4	532	1	530	0.0e+00	575	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
648932142	489	39.54	20	487	1	474	9.0e-117	414	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
648932144	437	24.2	28	422	2	387	9.0e-42	164	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648932145	439	26.96	37	404	1	373	1.0e-54	207	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648932147	684	29.75	176	668	136	643	4.0e-79	289	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
648932148	233	26.43	1	225	1	227	2.0e-37	149	COG2188	DNA-binding transcriptional regulator, GntR family	236
648932149	459	25.22	4	445	1	420	6.0e-50	192	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
648932150	401	42	5	399	6	397	9.0e-94	337	COG1228	Imidazolonepropionase or related amidohydrolase	406
648932151	518	59.08	1	501	1	498	0.0e+00	606	COG2986	Histidine ammonia-lyase	498
648932152	266	47.39	1	266	6	272	4.0e-85	307	COG3741	N-formylglutamate amidohydrolase	272
648932153	557	75.22	1	557	2	558	0.0e+00	1001	COG2987	Urocanate hydratase	561
648932154	362	37.67	1	353	1	359	4.0e-77	282	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
648932155	167	38.22	3	159	6	161	2.0e-26	111	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
648932159	513	41.35	40	507	6	450	6.0e-104	371	COG1115	Na+/alanine symporter	452
648932160	144	34.46	1	144	4	151	1.0e-12	65.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
648932161	152	40.67	1	150	6	154	2.0e-30	125	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648932162	152	52.29	1	152	4	155	7.0e-53	199	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
648932163	690	20.78	3	688	7	725	1.0e-35	145	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
648932164	201	32.78	19	193	13	189	4.0e-29	121	COG3963	Phospholipid N-methyltransferase	194
648932165	247	35.35	148	245	25	122	2.0e-15	76.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
648932169	326	25.39	110	302	58	231	1.0e-11	64.2	COG2801	Transposase InsO and inactivated derivatives	232
648932173	252	37.45	13	245	2	228	2.0e-46	179	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648932174	338	33.33	39	334	1	297	4.0e-51	195	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
648932175	725	31.04	151	713	1	535	1.0e-82	301	COG1178	ABC-type Fe3+ transport system, permease component	540
648932176	359	45.17	5	354	2	352	6.0e-112	397	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
648932182	308	44.73	33	307	21	286	4.0e-64	238	COG4976	Predicted methyltransferase, contains TPR repeat	287
648932187	146	41.77	68	146	9	87	2.0e-09	55.1	COG1987	Flagellar biosynthesis protein FliQ	89
648932193	256	28.05	31	251	3	204	2.0e-20	93.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
648932199	333	23.92	19	257	42	287	8.0e-15	74.8	COG0714	MoxR-like ATPase	329
648932201	391	22.5	3	348	5	351	1.0e-34	140	COG3864	Predicted metal-dependent peptidase	396
648932204	399	25.2	20	397	2	364	2.0e-37	150	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
648932211	466	30.02	9	464	5	433	2.0e-55	210	COG0305	Replicative DNA helicase	435
648932216	230	36.07	23	201	9	188	4.0e-36	144	COG4725	N6-adenosine-specific RNA methylase IME4	198
648932218	167	21.37	12	128	3	119	1.0e-05	43.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
648932227	231	23.04	1	204	13	223	8.0e-18	84.1	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
648932231	142	38.3	4	142	5	144	9.0e-22	96.2	COG3793	Tellurite resistance protein	144
648932239	64	39.34	1	61	2	61	3.0e-09	53.3	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
648932245	396	17.16	20	387	15	377	7.0e-19	88.8	COG4292	Low temperature requirement protein LtrA (function unknown)	387
648932246	164	46.28	41	161	5	123	5.0e-28	117	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
648932247	254	39.06	28	252	17	241	6.0e-53	200	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
648932248	146	28.26	1	126	1	138	7.0e-15	73.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
648932250	313	42.49	1	310	4	316	4.0e-71	261	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
648932251	259	48.28	33	259	8	237	3.0e-70	258	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
648932252	400	28.57	17	371	3	305	2.0e-33	137	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
648932253	343	31.76	1	340	3	295	1.0e-43	170	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
648932254	451	26.12	41	416	4	360	3.0e-39	156	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648932255	681	47.15	1	680	2	683	0.0e+00	801	COG0339	Zn-dependent oligopeptidase	683
648932256	132	34.23	22	132	15	124	6.0e-13	66.8	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
648932257	130	60.48	11	129	1	118	2.0e-34	137	COG3761	NADH:ubiquinone oxidoreductase 17.2 kD subunit	118
648932259	1227	19.44	6	744	1	601	1.0e-73	272	COG0209	Ribonucleotide reductase alpha subunit	696
648932262	722	24.9	12	522	7	480	9.0e-56	212	COG0286	Type I restriction-modification system, DNA methylase subunit	489
648932263	357	20.78	31	357	39	390	5.0e-15	75.5	COG0732	Restriction endonuclease S subunit	391
648932265	1143	25.99	358	1101	270	957	4.0e-81	297	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
648932269	647	31.95	212	639	151	588	1.0e-50	195	COG0465	ATP-dependent Zn proteases	596
648932280	205	29.63	53	187	10	134	6.0e-13	67.7	COG3415	Transposase	138
648932283	317	37.93	1	317	1	319	7.0e-64	237	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
648932285	494	47.36	1	490	3	494	1.0e-121	430	COG3333	TctA family transporter	504
648932286	524	33.33	6	452	2	474	3.0e-86	312	COG0405	Gamma-glutamyltranspeptidase	539
648932289	293	20.68	1	289	1	281	5.0e-19	88.7	COG3302	DMSO reductase anchor subunit	281
648932290	249	39.81	9	222	8	203	4.0e-50	191	COG0437	Fe-S-cluster-containing dehydrogenase component	203
648932291	945	22.39	20	914	42	763	2.0e-84	307	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
648932292	383	45.18	8	383	3	396	3.0e-107	382	COG0282	Acetate kinase	396
648932293	592	32.92	2	562	1	533	8.0e-116	411	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
648932294	489	33.4	14	489	1	458	1.0e-94	340	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
648932295	459	35.89	9	457	1	444	5.0e-112	398	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
648932297	331	29.48	6	328	8	332	9.0e-38	150	COG4521	ABC-type taurine transport system, periplasmic component	334
648932298	268	45.77	1	259	1	247	5.0e-79	287	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
648932299	420	42.36	192	420	33	257	3.0e-51	196	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
648932300	556	43.61	17	556	1	541	0.0e+00	511	COG2303	Choline dehydrogenase or related flavoprotein	542
648932301	410	23.87	26	323	3	284	6.0e-22	98.8	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648932302	222	21.25	59	218	13	169	1.0e-11	63	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648932303	453	35.61	55	449	5	374	8.0e-66	245	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648932304	257	37.5	15	254	5	244	5.0e-47	181	COG1414	DNA-binding transcriptional regulator, IclR family	246
648932305	312	34.34	1	265	3	259	7.0e-52	197	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
648932306	314	49.34	9	309	3	298	1.0e-88	319	COG3246	Uncharacterized conserved protein, DUF849 family	298
648932307	264	40.41	24	260	3	236	8.0e-41	160	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648932308	447	44	1	441	2	442	7.0e-96	344	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
648932309	196	33.14	23	195	16	172	1.0e-21	96.5	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
648932310	345	32.55	4	339	12	352	6.0e-63	234	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
648932311	222	33.93	1	222	5	227	3.0e-33	135	COG1802	DNA-binding transcriptional regulator, GntR family	230
648932312	508	45.61	159	499	3	331	3.0e-97	349	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
648932314	520	26.23	5	357	12	392	7.0e-45	175	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
648932315	625	43.41	24	609	6	603	0.0e+00	564	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
648932316	327	27.83	1	320	1	321	1.0e-41	163	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
648932317	746	46.37	177	731	73	633	1.0e-123	437	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
648932318	147	36.99	1	146	1	141	2.0e-33	135	COG4154	L-fucose mutarotase/ribose pyranase, RbsD/FucU family	144
648932319	561	42.36	7	547	39	580	3.0e-128	452	COG4425	Uncharacterized membrane protein	588
648932320	348	26.57	48	316	34	319	8.0e-30	124	COG4782	Esterase/lipase superfamily enzyme	377
648932321	196	28.93	77	196	4	110	4.0e-07	48	COG0607	Rhodanese-related sulfurtransferase	110
648932325	288	39.6	1	96	1	98	2.0e-11	63.4	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
648932333	694	40.52	6	545	1	538	0.0e+00	499	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
648932335	171	41.76	1	170	1	158	3.0e-46	177	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
648932337	427	33.42	49	427	3	379	1.0e-60	227	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648932339	345	25.28	1	254	1	260	2.0e-21	96.9	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648932340	282	44.58	12	258	16	264	3.0e-79	288	COG4336	Uncharacterized protein YcsI, UPF0317 family	265
648932341	292	25.17	1	292	1	292	1.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
648932343	403	26.85	32	389	7	345	7.0e-42	165	COG3457	Predicted amino acid racemase	353
648932344	317	41.75	12	317	7	312	2.0e-48	186	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
648932345	286	31.48	1	267	48	314	4.0e-24	105	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
648932346	419	28.21	6	414	1	408	1.0e-42	167	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648932349	383	30.99	6	382	4	383	7.0e-56	211	COG0006	Xaa-Pro aminopeptidase	384
648932353	437	29.01	43	421	1	384	9.0e-53	201	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648932354	98	55.95	1	82	1	84	1.0e-24	104	COG4311	Sarcosine oxidase delta subunit	97
648932355	983	36.18	589	983	1	379	2.0e-87	317	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
648932356	192	27.98	1	189	1	189	4.0e-19	88.1	COG4583	Sarcosine oxidase gamma subunit	189
648932357	334	24.37	21	324	33	341	4.0e-26	112	COG3391	DNA-binding beta-propeller fold protein YncE	381
648932358	433	19.44	57	395	3	349	2.0e-11	64	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648932361	332	29.64	8	324	18	348	9.0e-18	84.5	COG3391	DNA-binding beta-propeller fold protein YncE	381
648932362	281	22.22	11	152	8	148	1.0e-06	47.4	COG5501	Predicted secreted protein	148
648932364	302	18.08	25	273	2	248	3.0e-09	55.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
648932367	599	31.98	5	599	118	773	0.0e+00	570	COG4993	Glucose dehydrogenase	773
648932368	284	38.11	2	275	7	313	3.0e-66	245	COG0627	S-formylglutathione hydrolase FrmB	316
648932369	382	64.86	13	382	1	366	0.0e+00	542	COG1062	Zn-dependent alcohol dehydrogenase	366
648932371	345	24.68	82	305	14	241	4.0e-13	69.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648932374	288	43.2	42	165	25	148	6.0e-25	108	COG5501	Predicted secreted protein	148
648932377	750	26.02	289	605	21	336	6.0e-34	139	COG0642	Signal transduction histidine kinase	336
648932378	386	39.89	15	377	7	379	2.0e-72	266	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
648932379	240	34.15	15	219	2	203	5.0e-39	154	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
648932381	435	34.46	53	434	2	375	4.0e-67	248	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648932383	348	27.66	5	330	1	321	2.0e-41	163	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648932384	443	32.87	21	436	7	438	2.0e-75	276	COG0015	Adenylosuccinate lyase	438
648932385	277	28.24	1	276	1	298	2.0e-49	189	COG3246	Uncharacterized conserved protein, DUF849 family	298
648932386	207	49.28	4	207	22	226	9.0e-50	189	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
648932387	241	46.84	1	237	2	226	3.0e-64	238	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
648932388	140	35.48	6	126	1	124	2.0e-19	88.1	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
648932389	263	28.73	8	258	9	280	2.0e-24	106	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648932390	389	23.2	1	381	1	379	8.0e-58	218	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
648932391	306	30.23	6	305	1	297	1.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
648932393	1199	29.03	16	1198	1	1186	0.0e+00	676	COG3523	Type VI protein secretion system component VasK	1188
648932394	209	40	4	166	6	169	4.0e-40	158	COG3516	Predicted component of the type VI protein secretion system	169
648932395	497	51.91	1	495	1	492	0.0e+00	680	COG3517	Predicted component of the type VI protein secretion system	495
648932396	153	29.32	21	142	10	142	6.0e-11	60.4	COG3518	Predicted component of the type VI protein secretion system	157
648932397	592	36.82	4	592	7	621	2.0e-129	456	COG3519	Type VI protein secretion system component VasA	621
648932398	361	33.52	1	360	1	332	2.0e-68	252	COG3520	Predicted component of the type VI protein secretion system	335
648932402	173	27.63	1	152	1	136	3.0e-20	91.5	COG3521	Predicted component of the type VI protein secretion system	159
648932403	449	41.93	1	445	1	446	7.0e-125	440	COG3522	Predicted component of the type VI protein secretion system	446
648932404	268	36.4	18	251	4	239	1.0e-44	173	COG3455	Type VI protein secretion system component VasF	262
648932405	900	39.45	12	876	1	778	0.0e+00	733	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
648932406	537	42.82	183	530	123	463	5.0e-88	318	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
648932409	173	32.57	1	171	8	182	1.0e-27	115	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
648932410	255	16.67	4	253	3	254	5.0e-06	45.1	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
648932415	635	34.05	32	628	3	604	5.0e-128	452	COG2905	Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains	610
648932416	593	38.4	5	587	8	529	3.0e-121	429	COG4147	Na+(or H+)/acetate symporter ActP	529
648932417	86	43.53	2	86	5	88	4.0e-18	83.1	COG4327	Uncharacterized membrane protein	101
648932419	427	63.85	1	426	1	425	0.0e+00	658	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
648932420	361	38.42	22	361	2	320	1.0e-55	210	COG1612	Heme A synthase	323
648932423	372	20.61	40	331	3	246	4.0e-13	69.7	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
648932425	381	26.83	16	380	44	401	5.0e-38	152	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
648932426	781	29.82	6	461	3	452	3.0e-62	233	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
648932427	185	36.46	1	185	11	201	2.0e-33	135	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
648932428	407	24.94	4	379	1	380	1.0e-28	120	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648932429	501	42.55	267	501	1	226	1.0e-68	254	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
648932435	411	35.01	1	410	14	411	5.0e-67	248	COG2124	Cytochrome P450	411
648932436	382	21.33	58	343	4	225	2.0e-14	73.7	COG0584	Glycerophosphoryl diester phosphodiesterase	257
648932439	104	45.05	5	95	1	91	3.0e-25	106	COG0776	Bacterial nucleoid DNA-binding protein	94
648932440	325	58.9	4	325	2	322	4.0e-116	411	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
648932441	354	48.53	5	342	2	338	1.0e-113	403	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
648932443	214	44.63	41	214	1	177	4.0e-44	171	COG5452	Uncharacterized protein	180
648932444	145	31.03	1	138	4	147	6.0e-23	100	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
648932445	712	68.64	4	712	7	701	0.0e+00	852	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
648932446	406	22.49	6	405	1	394	3.0e-10	59.8	COG2814	Predicted arabinose efflux permease, MFS family	394
648932447	332	41.41	7	332	4	317	1.0e-70	260	COG0611	Thiamine monophosphate kinase	317
648932448	173	42.95	16	163	5	149	4.0e-31	127	COG0781	Transcription termination factor NusB	151
648932449	149	45.14	6	146	14	152	7.0e-33	132	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
648932450	203	48.29	1	203	1	198	5.0e-61	227	COG0307	Riboflavin synthase alpha chain	204
648932451	376	53.69	6	154	3	146	2.0e-48	186	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
648932452	158	59.18	1	147	1	147	3.0e-50	191	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
648932453	436	68.33	16	435	2	412	0.0e+00	678	COG0112	Glycine/serine hydroxymethyltransferase	413
648932462	251	30.98	13	245	5	257	3.0e-26	112	COG0584	Glycerophosphoryl diester phosphodiesterase	257
648932464	348	19.06	2	291	32	325	5.0e-22	98.6	COG3239	Fatty acid desaturase	343
648932466	212	41.67	19	209	1	192	9.0e-45	173	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
648932467	194	45.11	2	185	1	177	8.0e-38	150	COG3038	Cytochrome b561	181
648932468	191	28.34	13	191	5	190	7.0e-22	97.3	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
648932473	313	42.86	57	237	1	181	1.0e-37	150	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
648932475	554	37.66	51	357	1	297	5.0e-84	305	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
648932481	492	35.63	3	492	1	449	8.0e-73	268	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
648932483	196	24.38	1	194	6	206	2.0e-09	56	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
648932485	280	35.27	1	273	8	264	2.0e-56	212	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
648932488	204	42.86	40	203	66	229	3.0e-34	138	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
648932490	208	33.97	1	208	1	208	1.0e-23	103	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
648932491	121	57.89	8	121	4	117	8.0e-41	158	COG3536	Uncharacterized conserved protein, DUF971 family	120
648932493	486	42.8	8	478	2	461	1.0e-128	453	COG0415	Deoxyribodipyrimidine photolyase	461
648932494	391	45.32	63	391	2	322	2.0e-109	389	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
648932500	411	23.4	40	397	36	384	5.0e-26	112	COG2814	Predicted arabinose efflux permease, MFS family	394
648932504	264	24.59	57	236	53	224	8.0e-13	67.6	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
648932508	385	30.67	143	366	4	204	7.0e-35	141	COG2864	Cytochrome b subunit of formate dehydrogenase	218
648932513	207	29.08	16	204	8	197	3.0e-22	98.9	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
648932515	394	41.2	85	347	10	265	8.0e-57	214	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
648932516	226	27.01	1	203	6	212	6.0e-29	121	COG0300	Short-chain dehydrogenase	265
648932519	319	28.85	51	296	16	266	3.0e-50	192	COG1526	Formate dehydrogenase assembly factor FdhD	266
648932520	212	38.14	14	207	9	190	7.0e-36	143	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
648932521	182	49.07	10	168	4	161	7.0e-45	173	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
648932522	420	42.01	15	420	4	402	1.0e-102	367	COG0303	Molybdopterin biosynthesis enzyme	404
648932523	331	22.61	104	302	29	209	2.0e-12	66.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648932524	315	30.67	4	298	3	296	2.0e-39	156	COG0583	DNA-binding transcriptional regulator, LysR family	297
648932525	215	26.6	12	206	7	208	1.0e-21	96.4	COG0625	Glutathione S-transferase	211
648932527	258	39.56	1	258	1	270	2.0e-46	179	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
648932528	237	46.09	10	237	1	230	1.0e-68	252	COG4215	ABC-type arginine transport system, permease component	230
648932529	303	46.22	80	303	4	228	6.0e-70	257	COG4160	ABC-type arginine/histidine transport system, permease component	228
648932530	418	25.92	37	411	13	377	5.0e-47	182	COG0006	Xaa-Pro aminopeptidase	384
648932531	297	27.09	7	296	1	297	6.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
648932534	293	49.48	2	288	1	286	5.0e-89	321	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
648932536	187	46.71	26	176	4	154	1.0e-36	145	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648932537	319	36.59	27	311	5	284	5.0e-56	211	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
648932538	164	34.78	1	157	4	153	1.0e-27	116	COG4574	Serine protease inhibitor ecotin	162
648932543	206	28.29	1	205	7	202	5.0e-39	154	COG1573	Uracil-DNA glycosylase	202
648932544	512	30.03	164	495	12	332	5.0e-44	172	COG0642	Signal transduction histidine kinase	336
648932545	342	42.56	12	340	2	337	2.0e-81	296	COG2038	NaMN:DMB phosphoribosyltransferase	347
648932546	286	37.45	36	286	7	243	6.0e-32	131	COG0368	Cobalamin synthase	246
648932547	395	37.33	23	390	1	367	8.0e-75	274	COG4782	Esterase/lipase superfamily enzyme	377
648932548	407	37.74	32	342	1	314	4.0e-67	248	COG4782	Esterase/lipase superfamily enzyme	377
648932550	237	34.98	39	237	13	215	7.0e-37	147	COG3577	Predicted aspartyl protease	215
648932553	508	44.38	89	247	1	157	2.0e-28	120	COG3436	Transposase	157
648932558	353	37.15	13	328	11	317	4.0e-77	282	COG0042	tRNA-dihydrouridine synthase	323
648932560	404	52.02	20	404	8	395	1.0e-130	460	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
648932561	664	24.94	263	662	31	404	7.0e-28	119	COG0840	Methyl-accepting chemotaxis protein	408
648932565	690	37.04	64	325	73	341	5.0e-39	156	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
648932567	180	58.38	1	172	4	165	2.0e-63	235	COG0678	Peroxiredoxin	165
648932568	336	31.83	1	323	6	334	2.0e-47	183	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
648932572	385	42.74	6	380	1	346	7.0e-77	281	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
648932574	562	36.3	1	561	1	553	3.0e-106	379	COG4987	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components	573
648932575	608	39.61	43	603	2	527	8.0e-123	434	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
648932578	499	39.38	4	486	1	472	1.0e-122	433	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648932582	293	31.54	1	290	1	296	4.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
648932585	182	24.29	2	170	1	173	2.0e-15	75.3	COG0563	Adenylate kinase or related kinase	178
648932586	265	41.53	1	247	36	276	5.0e-64	237	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
648932587	298	36.36	1	298	7	307	9.0e-50	190	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
648932592	184	32.03	53	179	1	125	4.0e-12	64.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
648932593	223	20.64	10	223	46	259	9.0e-13	67.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
648932594	630	50.08	16	630	1	615	0.0e+00	597	COG3211	Secreted phosphatase, PhoX family	616
648932596	726	34.07	17	511	1	462	1.0e-110	394	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
648932598	161	25.15	7	161	5	152	1.0e-07	49.9	COG3153	Predicted N-acetyltransferase YhbS	171
648932599	361	22.22	1	167	1	178	2.0e-13	70.8	COG1988	Membrane-bound metal-dependent hydrolase YbcI, DUF457 family	190
648932600	353	26.4	24	352	7	352	4.0e-31	128	COG4188	Predicted dienelactone hydrolase	365
648932601	337	22.5	219	337	3	122	5.0e-11	62.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
648932602	614	52.27	1	614	8	573	0.0e+00	768	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
648932603	409	26.71	205	350	1	145	3.0e-13	69.8	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
648932606	236	49.15	2	235	1	236	4.0e-74	271	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
648932607	250	47.6	1	246	1	250	2.0e-72	265	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
648932608	313	38.02	8	313	3	313	6.0e-41	161	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
648932610	353	30	15	345	1	340	2.0e-41	162	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648932611	352	23.84	200	345	10	158	6.0e-06	45.4	COG3807	SH3-like domain	171
648932613	394	43.2	6	326	11	339	9.0e-86	310	COG2951	Membrane-bound lytic murein transglycosylase B	343
648932614	360	48.88	3	355	2	352	2.0e-102	366	COG4148	ABC-type molybdate transport system, ATPase component	352
648932615	229	52.65	3	227	1	225	6.0e-60	223	COG4149	ABC-type molybdate transport system, permease component	225
648932616	275	43.35	7	268	1	256	3.0e-53	202	COG0725	ABC-type molybdate transport system, periplasmic component	258
648932618	255	36.05	9	251	8	251	6.0e-28	118	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648932619	450	26.42	228	439	10	206	6.0e-20	92.5	COG2114	Adenylate cyclase, class 3	227
648932620	276	23.44	4	275	5	268	1.0e-28	120	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
648932622	864	24.5	3	455	2	437	4.0e-42	167	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
648932624	406	42.25	2	400	6	398	5.0e-102	364	COG4671	Predicted glycosyl transferase	400
648932625	406	26.47	117	406	82	378	2.0e-30	127	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648932626	370	23.9	1	364	1	381	3.0e-30	126	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648932627	384	31.88	5	383	12	393	2.0e-57	216	COG4671	Predicted glycosyl transferase	400
648932634	166	31.95	4	155	6	174	4.0e-23	101	COG0225	Peptide methionine sulfoxide reductase MsrA	174
648932637	395	45.06	163	395	60	286	5.0e-64	238	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648932638	341	35.91	1	337	1	317	2.0e-66	246	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648932639	629	23.87	1	613	4	548	4.0e-54	206	COG0747	ABC-type transport system, periplasmic component	556
648932640	628	52.28	1	570	3	539	0.0e+00	654	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
648932641	632	30.12	374	621	3	227	2.0e-28	121	COG2114	Adenylate cyclase, class 3	227
648932643	339	50.59	1	338	4	335	2.0e-114	405	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
648932645	281	17.09	12	257	17	286	2.0e-11	63	COG0657	Acetyl esterase/lipase	312
648932646	300	35.96	10	300	12	294	2.0e-50	192	COG1597	Diacylglycerol kinase family enzyme	301
648932647	880	35.16	1	874	4	859	0.0e+00	578	COG0308	Aminopeptidase N	859
648932648	790	29.27	499	784	59	335	2.0e-43	171	COG0642	Signal transduction histidine kinase	336
648932649	997	40.29	44	989	25	962	0.0e+00	834	COG1391	Glutamine synthetase adenylyltransferase	963
648932650	473	28.86	134	473	3	335	5.0e-34	139	COG0642	Signal transduction histidine kinase	336
648932651	228	42.11	3	226	2	228	5.0e-57	214	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648932652	380	48.2	1	275	71	346	3.0e-63	235	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
648932653	217	25.24	5	200	1	203	1.0e-17	83.3	COG0625	Glutathione S-transferase	211
648932654	127	36.43	1	127	3	130	1.0e-22	98.6	COG3791	Uncharacterized conserved protein	133
648932655	413	25.69	271	412	4	134	5.0e-16	79.3	COG1765	Uncharacterized OsmC-related protein	137
648932656	158	44.3	1	156	1	153	3.0e-38	150	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
648932658	151	52.38	6	150	1	147	8.0e-44	169	COG2332	Cytochrome c-type biogenesis protein CcmE	153
648932659	377	32.75	1	286	1	287	1.0e-46	180	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
648932661	144	24.63	12	143	2	135	3.0e-09	54.6	COG4520	Surface antigen	136
648932662	454	23.91	166	452	36	328	2.0e-26	114	COG0642	Signal transduction histidine kinase	336
648932666	262	35.59	68	236	4	179	8.0e-32	131	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
648932669	352	40.06	5	352	2	353	2.0e-82	299	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
648932671	237	25.6	42	208	19	186	2.0e-19	89.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648932672	571	34.83	27	560	8	533	1.0e-94	341	COG1283	Na+/phosphate symporter	533
648932673	311	37.83	1	304	1	301	2.0e-56	212	COG1893	Ketopantoate reductase	307
648932674	280	21.4	25	280	30	278	1.0e-27	117	COG3176	Putative hemolysin	292
648932675	656	53.76	34	656	1	586	0.0e+00	753	COG0441	Threonyl-tRNA synthetase	589
648932677	115	39.29	19	102	8	91	3.0e-22	97	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
648932679	160	40.43	5	145	3	136	2.0e-32	131	COG3019	Uncharacterized conserved protein	149
648932683	315	18.02	48	314	1	280	2.0e-15	77	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648932684	152	31.54	1	148	2	150	2.0e-32	131	COG0822	NifU homolog involved in Fe-S cluster formation	150
648932685	211	52.79	15	209	1	195	3.0e-72	264	COG0302	GTP cyclohydrolase I	195
648932686	151	52.68	13	124	1	111	9.0e-39	152	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
648932689	251	23.36	8	251	2	217	1.0e-15	77.1	COG0705	Membrane associated serine protease, rhomboid family	228
648932691	215	37.72	1	167	21	187	2.0e-34	138	COG5388	Uncharacterized protein	209
648932694	204	45.83	1	192	3	191	3.0e-56	211	COG3672	Predicted transglutaminase-like cysteine proteinase	191
648932697	176	54.09	18	176	17	175	3.0e-54	204	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
648932701	281	60	86	270	2	186	5.0e-69	254	COG1045	Serine acetyltransferase	194
648932702	271	38.43	15	268	7	257	3.0e-41	162	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648932703	277	27.43	1	273	11	296	2.0e-28	119	COG0583	DNA-binding transcriptional regulator, LysR family	297
648932705	205	29.63	53	187	10	134	6.0e-13	67.7	COG3415	Transposase	138
648932706	288	24.26	20	281	5	271	7.0e-21	94.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648932707	291	22.11	7	285	3	280	2.0e-18	86.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648932708	249	26.22	1	249	2	282	2.0e-17	83.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648932709	129	57.38	49	109	1	61	5.0e-18	83.5	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
648932710	400	26.7	7	382	1	369	9.0e-48	184	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
648932711	250	35.89	10	245	2	249	1.0e-56	212	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
648932712	169	24.86	6	156	14	177	1.0e-24	105	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
648932713	221	40.26	1	221	2	231	1.0e-39	156	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
648932714	241	50.43	8	239	1	228	6.0e-78	284	COG1489	DNA-binding protein, stimulates sugar fermentation	235
648932715	481	34.82	3	481	2	488	5.0e-79	288	COG0168	Trk-type K+ transport system, membrane component	499
648932716	331	36.7	12	328	37	363	3.0e-58	219	COG4269	Uncharacterized membrane protein YjgN, DUF898 family	364
648932721	368	27.32	1	357	1	345	2.0e-45	176	COG3177	Fic family protein	348
648932722	592	28.97	23	592	4	544	6.0e-77	282	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
648932734	276	46.61	18	265	3	253	2.0e-89	322	COG0024	Methionine aminopeptidase	255
648932735	237	39.17	21	237	8	224	9.0e-58	216	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
648932736	758	33.48	281	731	173	641	3.0e-88	320	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
648932737	316	40.26	1	297	2	300	7.0e-64	237	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
648932738	889	27.83	5	885	1	740	0.0e+00	643	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
648932741	293	37.77	13	289	7	280	1.0e-65	243	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
648932746	268	26.1	12	258	6	243	4.0e-39	155	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
648932747	90	53.33	1	90	1	90	7.0e-28	115	COG5425	Usg protein (tryptophan operon, function unknown)	90
648932749	314	28.62	1	266	5	255	1.0e-35	143	COG0714	MoxR-like ATPase	329
648932750	409	44.96	8	390	4	389	2.0e-96	346	COG3552	Uncharacterized conserved protein, contains von Willebrand factor type A (vWA) domain	395
648932752	358	37.18	3	349	1	355	2.0e-57	216	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648932753	269	34.59	112	267	6	162	1.0e-33	137	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
648932754	333	44.07	1	333	10	348	3.0e-69	255	COG3191	L-aminopeptidase/D-esterase	348
648932755	1172	28.41	23	706	1	637	0.0e+00	494	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
648932756	159	43.33	7	156	6	154	3.0e-26	111	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648932757	417	26.68	1	416	2	384	2.0e-41	163	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648932758	325	22.05	21	281	16	271	8.0e-07	48.3	COG0385	Predicted Na+-dependent transporter	319
648932759	242	26.14	3	239	1	225	5.0e-24	104	COG5497	Predicted secreted protein	228
648932760	223	56.36	5	223	4	220	3.0e-84	304	COG0036	Pentose-5-phosphate-3-epimerase	220
648932765	150	33.64	32	138	17	122	6.0e-10	56.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
648932766	442	49.21	1	441	1	438	0.0e+00	527	COG0015	Adenylosuccinate lyase	438
648932767	249	26.26	1	179	2	140	2.0e-13	69.6	COG0622	Predicted phosphodiesterase	172
648932768	184	45	4	183	1	179	3.0e-50	191	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
648932771	261	26.7	85	258	32	207	1.0e-28	120	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
648932772	256	32.8	4	253	5	252	1.0e-54	206	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
648932773	121	66.98	15	120	1	104	2.0e-31	127	COG5467	Uncharacterized protein	104
648932775	254	53.6	1	249	1	247	3.0e-91	327	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
648932777	79	53.16	1	79	2	80	7.0e-26	108	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
648932779	221	52.84	1	221	3	230	6.0e-82	297	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
648932780	80	39.74	1	78	1	78	3.0e-13	66.9	COG5460	Uncharacterized conserved protein, DUF2164 family	82
648932781	271	40.19	166	271	18	124	2.0e-19	89.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
648932782	732	51.15	2	723	8	743	0.0e+00	902	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
648932783	77	42.35	1	77	1	85	4.0e-19	86.2	COG0271	Stress-induced morphogen (activity unknown)	90
648932784	110	56.73	1	103	2	105	9.0e-41	158	COG0278	Glutaredoxin-related protein	105
648932786	520	30.65	324	519	30	218	7.0e-28	119	COG2114	Adenylate cyclase, class 3	227
648932787	312	31.78	29	283	1	246	4.0e-44	171	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
648932791	205	47.6	1	205	1	205	1.0e-55	209	COG0522	Ribosomal protein S4 or related protein	205
648932792	267	38.93	2	261	3	258	4.0e-68	251	COG0796	Glutamate racemase	269
648932793	293	42.8	43	285	5	241	9.0e-66	243	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
648932794	188	31.58	16	186	16	185	1.0e-15	76.7	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
648932798	123	40.83	1	120	1	120	1.0e-24	104	COG3795	Uncharacterized conserved protein	123
648932799	418	38.54	11	418	4	410	1.0e-85	310	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
648932801	743	68.74	4	742	3	739	0.0e+00	1125	COG2838	Monomeric isocitrate dehydrogenase	744
648932802	289	26.74	7	285	2	287	6.0e-27	114	COG0583	DNA-binding transcriptional regulator, LysR family	297
648932803	203	35.61	1	201	3	206	4.0e-29	121	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
648932804	275	25.53	184	275	5	98	4.0e-11	61.9	COG2388	Predicted acetyltransferase, GNAT superfamily	99
648932809	400	41.9	1	398	1	397	2.0e-76	280	COG0786	Na+/glutamate symporter	404
648932810	105	35	1	99	2	101	7.0e-20	88.8	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
648932811	744	71.29	2	743	11	730	0.0e+00	1144	COG0376	Catalase (peroxidase I)	730
648932812	305	35.03	4	295	1	292	1.0e-41	164	COG0583	DNA-binding transcriptional regulator, LysR family	297
648932814	658	26.18	259	655	32	403	2.0e-27	117	COG0840	Methyl-accepting chemotaxis protein	408
648932815	403	33.02	1	399	14	407	2.0e-128	452	COG0538	Isocitrate dehydrogenase	407
648932816	333	35.24	5	333	1	329	4.0e-73	268	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
648932818	132	45.04	1	131	1	131	7.0e-30	122	COG5395	Uncharacterized membrane protein	131
648932819	204	33.5	4	195	1	203	2.0e-28	119	COG0625	Glutathione S-transferase	211
648932822	888	53.8	1	888	5	879	0.0e+00	1127	COG0013	Alanyl-tRNA synthetase	879
648932823	355	65.48	14	290	5	277	4.0e-87	315	COG0468	RecA/RadA recombinase	279
648932824	311	25.89	12	311	1	307	2.0e-29	122	COG0524	Sugar or nucleoside kinase, ribokinase family	311
648932825	317	63.3	5	301	9	305	3.0e-109	388	COG2313	Pseudouridine-5'-phosphate glycosidase (pseudoU degradation)	310
648932832	205	26.67	15	204	1	192	6.0e-15	74.3	COG0558	Phosphatidylglycerophosphate synthase	192
648932833	306	49.67	8	306	7	303	5.0e-81	294	COG4589	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase	303
648932834	209	26.13	5	202	37	225	7.0e-18	84.2	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
648932835	439	37.89	28	188	10	170	3.0e-28	119	COG2059	Chromate transport protein ChrA	195
648932836	272	61.54	120	262	1	143	5.0e-53	201	COG4275	Uncharacterized protein	143
648932838	359	45.35	2	355	1	355	6.0e-101	361	COG1377	Flagellar biosynthesis protein FlhB	363
648932839	257	32.27	1	251	1	247	2.0e-30	126	COG1684	Flagellar biosynthesis protein FliR	258
648932840	88	48.84	1	86	1	86	5.0e-13	65.9	COG1987	Flagellar biosynthesis protein FliQ	89
648932841	110	23.33	22	110	16	105	1.0e-06	45.3	COG1677	Flagellar hook-basal body complex protein FliE	105
648932842	136	44.93	1	135	1	137	9.0e-40	155	COG1558	Flagellar basal body rod protein FlgC	137
648932843	138	25	6	137	1	133	1.0e-16	79.2	COG1815	Flagellar basal body rod protein FlgB	133
648932846	231	66.04	17	228	36	247	3.0e-73	268	COG1338	Flagellar biosynthetic protein FliP	248
648932848	252	28.1	80	232	35	186	2.0e-09	56.2	COG3334	Flagellar motility protein MotE, a chaperone for MotC folding	192
648932850	410	29.91	77	392	4	323	3.0e-52	199	COG1868	Flagellar motor switch protein FliM	332
648932851	169	32.72	9	169	1	159	1.0e-18	86.1	COG1580	Flagellar basal body-associated protein FliL	159
648932853	246	40.38	1	242	1	265	9.0e-49	187	COG4786	Flagellar basal body rod protein FlgG	265
648932854	260	51.7	1	260	2	264	2.0e-76	278	COG4786	Flagellar basal body rod protein FlgG	265
648932856	250	37.08	8	247	1	230	5.0e-52	197	COG2063	Flagellar basal body L-ring protein FlgH	230
648932857	138	58.33	18	137	1	120	2.0e-26	111	COG1734	RNA polymerase-binding transcription factor DksA	120
648932859	390	52.73	26	390	3	365	1.0e-109	390	COG1706	Flagellar basal body P-ring protein FlgI	365
648932863	388	21.16	12	388	11	360	1.0e-16	80.9	COG1344	Flagellin and related hook-associated protein FlgL	360
648932864	385	18.92	17	385	16	360	4.0e-19	89.4	COG1344	Flagellin and related hook-associated protein FlgL	360
648932865	387	19.95	13	387	11	359	4.0e-19	89.4	COG1344	Flagellin and related hook-associated protein FlgL	360
648932866	501	21.09	4	277	3	272	3.0e-11	63.6	COG1344	Flagellin and related hook-associated protein FlgL	360
648932867	501	19.39	17	278	16	276	1.0e-09	58.2	COG1344	Flagellin and related hook-associated protein FlgL	360
648932868	162	23.97	1	139	3	147	2.0e-15	75	COG5443	Flagellar biosynthesis regulator FlbT	148
648932869	97	27.17	2	93	27	115	2.0e-09	53.8	COG5442	Flagellar biosynthesis regulator FlaF	115
648932875	617	23.67	1	617	1	551	6.0e-43	169	COG1256	Flagellar hook-associated protein FlgK	552
648932876	459	30.32	3	459	1	423	6.0e-53	202	COG1749	Flagellar hook protein FlgE	423
648932877	281	24	1	265	18	278	1.0e-32	134	COG0714	MoxR-like ATPase	329
648932879	172	27.22	1	169	1	163	7.0e-27	113	COG2062	Phosphohistidine phosphatase SixA	163
648932880	299	29.9	15	293	22	322	2.0e-35	142	COG2367	Beta-lactamase class A	329
648932882	504	43.92	7	504	1	467	0.0e+00	539	COG3106	Predicted ATPase, YcjX-like family	467
648932883	354	41.98	14	351	5	347	2.0e-80	292	COG3768	Uncharacterized membrane protein YcjF, UPF0283 family	350
648932885	392	63.27	1	391	1	392	0.0e+00	567	COG3825	Uncharacterized conserved protein,  contains von Willebrand factor type A (vWA) domain	393
648932886	328	63.25	58	291	37	270	1.0e-98	353	COG2326	Polyphosphate kinase 2, PPK2 family	270
648932887	143	33.55	1	141	4	152	3.0e-12	64.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
648932888	262	33.05	139	255	1	118	2.0e-18	86.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
648932891	123	41.51	18	122	1	102	2.0e-17	81.3	COG0633	Ferredoxin	102
648932896	327	21.6	20	299	6	292	4.0e-09	56	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
648932897	156	27.68	32	143	6	117	5.0e-14	70.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
648932898	194	36.22	2	193	8	203	3.0e-33	135	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
648932899	667	21.19	1	332	1	332	6.0e-27	116	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
648932900	267	57.89	17	263	4	250	1.0e-96	346	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
648932901	382	39.11	112	382	2	267	1.0e-59	223	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
648932902	337	40.23	1	333	4	338	7.0e-75	274	COG3367	Uncharacterized conserved protein, NAD-dependent epimerase/dehydratase family	339
648932903	328	29.03	17	328	17	355	3.0e-45	176	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
648932904	392	20.17	28	384	34	391	1.0e-05	44.4	COG2814	Predicted arabinose efflux permease, MFS family	394
648932905	413	29.76	106	237	53	213	7.0e-06	45.7	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
648932907	443	25.52	166	437	117	406	1.0e-24	108	COG0840	Methyl-accepting chemotaxis protein	408
648932908	333	42.51	7	331	2	325	1.0e-85	310	COG1171	Threonine dehydratase	347
648932909	263	30.8	2	245	98	372	4.0e-25	108	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648932911	266	41.18	13	247	1	234	4.0e-66	244	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
648932912	259	33.72	3	254	1	250	6.0e-33	134	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648932913	443	30.26	5	443	1	440	3.0e-67	249	COG2067	Long-chain fatty acid transport protein	440
648932915	275	57.79	1	244	2	244	7.0e-86	310	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
648932918	315	27.01	161	295	8	140	6.0e-06	45.2	COG2510	Uncharacterized membrane protein	140
648932921	263	38.33	13	248	13	251	1.0e-41	163	COG1484	DNA replication protein DnaC	254
648932922	526	28.15	22	289	7	257	2.0e-17	84	COG4584	Transposase	278
648932924	768	37.01	6	765	1	731	0.0e+00	541	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
648932926	347	31.38	14	322	7	331	3.0e-46	179	COG3608	Predicted deacylase	331
648932927	301	34.28	1	292	1	317	9.0e-61	227	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
648932928	183	36.73	3	146	13	158	7.0e-28	116	COG4067	Uncharacterized conserved protein	162
648932930	313	50.64	2	313	1	310	2.0e-111	395	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
648932931	523	23.29	13	517	10	536	1.0e-54	207	COG2303	Choline dehydrogenase or related flavoprotein	542
648932934	96	43.75	1	80	1	76	9.0e-15	71.9	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
648932935	194	31.62	8	132	2	137	1.0e-09	56.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
648932936	322	20.49	28	307	5	292	1.0e-08	54.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
648932937	350	21.14	19	329	30	370	2.0e-25	109	COG1680	CubicO group peptidase, beta-lactamase class C family	390
648932938	293	33.8	71	284	2	214	2.0e-30	126	COG1910	Periplasmic molybdate-binding protein/domain	223
648932939	572	37.68	24	565	5	530	3.0e-125	442	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648932941	384	32.05	1	384	2	373	1.0e-77	284	COG4637	Predicted ATPase	373
648932942	569	55.54	12	569	14	581	0.0e+00	674	COG1001	Adenine deaminase	584
648932943	429	29.62	83	391	1	306	8.0e-36	144	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
648932944	338	28	1	325	10	316	4.0e-37	148	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
648932945	360	38.8	42	357	4	311	4.0e-57	215	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
648932947	315	31.52	1	315	1	311	7.0e-36	144	COG0524	Sugar or nucleoside kinase, ribokinase family	311
648932948	490	58.14	8	488	5	483	0.0e+00	691	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
648932949	606	38.98	10	606	5	573	0.0e+00	605	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
648932950	212	47.37	3	210	1	208	3.0e-54	205	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
648932952	542	50.3	42	532	3	446	0.0e+00	528	COG0166	Glucose-6-phosphate isomerase	446
648932956	380	62.47	1	373	1	371	0.0e+00	474	COG0686	Alanine dehydrogenase	371
648932957	155	45.39	1	152	4	154	4.0e-30	124	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648932959	294	38.93	1	291	12	307	3.0e-61	229	COG3386	Sugar lactone lactonase YvrE	307
648932961	262	55.83	1	239	2	240	1.0e-93	336	COG1054	Predicted sulfurtransferase	308
648932970	202	30.25	29	190	28	182	1.0e-12	66.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
648932973	342	26.43	83	306	1	221	1.0e-25	110	COG0543	NAD(P)H-flavin reductase	252
648932975	267	23.1	1	265	12	313	2.0e-14	73.2	COG0226	ABC-type phosphate transport system, periplasmic component	318
648932976	433	41.16	31	355	4	323	3.0e-78	286	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
648932978	190	50	23	190	4	163	3.0e-45	175	COG0440	Acetolactate synthase, small subunit	163
648932979	591	51.32	4	568	1	549	0.0e+00	653	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
648932983	404	38.13	6	375	1	321	1.0e-84	307	COG0523	GTPase, G3E family	323
648932985	308	30.07	12	305	3	305	9.0e-32	130	COG1715	Restriction endonuclease Mrr	308
648932991	526	26.77	22	289	7	257	2.0e-17	84.3	COG4584	Transposase	278
648932992	263	38.33	13	248	13	251	1.0e-41	163	COG1484	DNA replication protein DnaC	254
648933003	270	35.27	15	266	15	247	6.0e-39	154	COG3926	Lysozyme family protein	252
648933010	327	32	1	324	5	340	9.0e-41	160	COG3500	Phage protein D	350
648933011	78	39.13	4	72	2	67	1.0e-09	55	COG5004	P2-like prophage tail protein X	70
648933012	136	26.02	5	127	2	123	2.0e-17	81.5	COG3499	Phage protein U	147
648933016	170	29.07	1	168	1	168	1.0e-15	76.1	COG3498	Phage tail tube protein FII	169
648933017	409	29.7	1	394	1	394	2.0e-45	177	COG3497	Phage tail sheath protein FI	394
648933020	265	28.69	129	246	6	125	5.0e-10	58.4	COG4675	Microcystin-dependent protein  (function unknown)	170
648933023	303	40.51	7	272	7	278	5.0e-51	194	COG3948	Phage-related baseplate assembly protein	306
648933029	149	28.57	1	145	1	135	2.0e-17	81.6	COG4387	Mu-like prophage protein gp36	139
648933031	299	46.43	1	298	2	308	3.0e-83	301	COG4397	Mu-like prophage major head subunit gpT	308
648933033	344	25.28	11	336	9	355	9.0e-23	101	COG4388	Mu-like prophage I protein	357
648933034	396	21.66	9	235	2	315	3.0e-12	66.3	COG2369	Uncharacterized conserved protein, contains phage Mu gpF-like domain	432
648933035	509	29.88	13	497	10	503	5.0e-75	275	COG4383	Mu-like prophage protein gp29	517
648933036	547	38.9	27	533	3	499	3.0e-112	399	COG4373	Mu-like prophage FluMu protein gp28	509
648933066	383	26	86	381	106	405	1.0e-17	84.7	COG0840	Methyl-accepting chemotaxis protein	408
648933070	249	40.41	6	248	2	240	2.0e-72	265	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
648933071	192	25.41	1	176	1	176	4.0e-15	74.6	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
648933072	116	50	1	106	1	102	3.0e-31	127	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
648933073	197	35.82	3	193	2	188	2.0e-26	112	COG0693	Putative intracellular protease/amidase	188
648933074	665	33.54	24	656	24	647	1.0e-119	424	COG3733	Cu2+-containing amine oxidase	654
648933075	296	49.05	78	287	3	212	9.0e-58	217	COG0560	Phosphoserine phosphatase	212
648933076	322	43.54	14	304	1	292	2.0e-75	276	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
648933077	180	18.34	6	166	5	173	8.0e-08	50.4	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648933080	191	27.32	6	176	5	187	5.0e-16	77.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648933081	516	51.09	6	416	1	409	2.0e-120	426	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
648933083	303	42.57	1	303	2	291	5.0e-72	264	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
648933085	354	21.8	7	346	3	340	2.0e-10	60.4	COG5330	Uncharacterized conserved protein, DUF2336 family	364
648933086	300	38.61	1	299	2	276	1.0e-61	230	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
648933088	306	37.86	1	306	1	293	6.0e-69	254	COG1131	ABC-type multidrug transport system, ATPase component	293
648933089	253	22.42	24	246	42	253	4.0e-08	52.1	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
648933091	508	44.38	89	247	1	157	2.0e-28	120	COG3436	Transposase	157
648933094	432	20.11	76	249	17	174	1.0e-05	44.7	COG4961	Flp pilus assembly protein TadG	185
648933096	339	63.5	1	337	3	338	0.0e+00	542	COG0059	Ketol-acid reductoisomerase	338
648933097	217	22.75	23	211	13	196	2.0e-06	45.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648933098	496	42.32	12	380	5	347	2.0e-74	273	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
648933099	61	44.07	3	61	4	62	3.0e-06	43.7	COG3242	Uncharacterized conserved protein YjeT, DUF2065 family	62
648933100	295	29.25	1	287	1	290	3.0e-44	172	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
648933101	394	28.57	74	363	2	274	2.0e-45	176	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
648933102	157	43.45	13	155	7	150	9.0e-40	156	COG2153	Predicted N-acyltransferase, GNAT family	155
648933103	171	44.19	4	168	2	167	7.0e-40	156	COG0262	Dihydrofolate reductase	167
648933104	264	71.05	1	264	3	268	8.0e-123	433	COG0207	Thymidylate synthase	268
648933105	158	62.7	9	134	1	126	9.0e-49	185	COG3814	Uncharacterized protein	157
648933119	945	20.79	248	924	24	688	5.0e-55	210	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
648933125	188	35.15	1	184	1	202	3.0e-25	108	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
648933126	89	32.56	4	89	2	87	1.0e-06	45.1	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
648933127	101	35.11	6	99	4	96	3.0e-08	50.4	COG3668	Plasmid stabilization system protein ParE	98
648933147	596	24.46	9	239	1	214	1.0e-17	85.6	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
648933150	429	59.21	1	429	1	420	0.0e+00	614	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
648933153	431	55.22	2	431	1	423	0.0e+00	543	COG0141	Histidinol dehydrogenase	425
648933154	167	64.78	9	167	3	160	1.0e-60	226	COG5328	Uncharacterized protein, UPF0262 family	160
648933155	150	33.58	11	142	5	139	4.0e-25	107	COG0394	Protein-tyrosine-phosphatase	139
648933156	72	65.28	1	72	1	72	5.0e-24	102	COG0361	Translation initiation factor IF-1	75
648933157	208	44.67	5	201	3	193	5.0e-54	204	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
648933158	65	38.33	9	64	4	62	4.0e-06	43.1	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
648933160	536	34.62	4	528	1	504	6.0e-85	308	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
648933164	300	25.75	1	293	1	295	8.0e-30	124	COG0583	DNA-binding transcriptional regulator, LysR family	297
648933165	302	27.3	1	287	1	289	9.0e-27	114	COG0583	DNA-binding transcriptional regulator, LysR family	297
648933166	214	26.8	39	191	2	136	3.0e-13	68.7	COG1225	Peroxiredoxin	157
648933168	314	40.83	198	314	14	130	3.0e-25	109	COG3474	Cytochrome c2	135
648933175	271	23.26	48	257	22	221	2.0e-08	53.1	COG2801	Transposase InsO and inactivated derivatives	232
648933178	283	32.95	26	282	1	217	2.0e-45	175	COG0850	Septum formation inhibitor MinC	219
648933179	273	59.19	4	273	2	272	8.0e-110	389	COG2894	Septum formation inhibitor-activating ATPase MinD	272
648933180	84	38.82	1	84	1	84	1.0e-16	77.9	COG0851	Septum formation topological specificity factor MinE	88
648933181	383	23.66	6	352	7	319	7.0e-35	141	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
648933182	352	39.76	17	350	1	333	1.0e-48	187	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
648933183	255	44.3	1	235	1	236	8.0e-65	240	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
648933184	532	55.68	1	527	1	527	0.0e+00	748	COG4108	Peptide chain release factor RF-3	528
648933189	333	39.3	1	303	41	337	2.0e-68	252	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
648933190	235	25.55	1	186	2	227	2.0e-17	82.5	COG1192	Cellulose biosynthesis protein BcsQ	259
648933193	293	25	5	293	2	295	2.0e-20	93.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
648933197	113	31.2	3	113	2	126	9.0e-14	68.8	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
648933198	212	28.64	11	199	18	226	2.0e-13	69.5	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
648933199	452	20.5	6	437	4	383	5.0e-13	69.2	COG4872	Uncharacterized membrane protein	394
648933200	192	22.8	12	187	1	190	6.0e-13	67.7	COG4929	Uncharacterized membrane-anchored protein	190
648933201	351	34.54	43	344	6	300	1.0e-54	207	COG2813	16S rRNA G1207 methylase RsmC	300
648933202	233	37.19	1	232	3	243	2.0e-51	195	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
648933205	605	39.74	3	496	1	529	6.0e-130	458	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
648933207	528	38.82	1	511	4	544	2.0e-115	409	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
648933208	307	44.62	1	306	1	315	7.0e-78	283	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648933209	375	45.5	155	375	66	287	3.0e-69	255	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648933210	539	61.39	2	529	1	531	0.0e+00	779	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
648933211	239	31.16	19	217	13	210	4.0e-28	118	COG1802	DNA-binding transcriptional regulator, GntR family	230
648933212	353	39.13	10	353	1	310	2.0e-75	276	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
648933213	235	37.33	13	230	9	231	4.0e-36	144	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
648933215	346	57.48	1	340	1	339	0.0e+00	492	COG3938	Proline racemase	341
648933216	263	33.75	89	247	7	164	6.0e-26	111	COG1510	DNA-binding transcriptional regulator GbsR, MarR family	177
648933219	251	23.81	20	207	1	169	5.0e-09	55	COG3806	Anti-sigma factor ChrR, cupin superfamily	216
648933220	490	20.25	18	458	1	475	1.0e-15	78.1	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
648933224	457	56.71	20	451	2	427	0.0e+00	561	COG3508	Homogentisate 1,2-dioxygenase	427
648933225	338	29.04	4	336	1	266	1.0e-43	170	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
648933227	316	18.32	38	233	30	224	1.0e-09	57.6	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648933228	536	23.98	25	412	2	385	2.0e-50	194	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
648933235	144	46.22	11	129	8	126	5.0e-39	153	COG5349	Uncharacterized conserved protein, DUF983 family	126
648933236	508	44.38	89	247	1	157	2.0e-28	120	COG3436	Transposase	157
648933240	285	45.79	10	278	3	265	3.0e-66	245	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
648933241	304	35.9	1	304	9	261	2.0e-57	216	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
648933242	645	65.26	21	446	1	426	0.0e+00	653	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
648933246	274	31.46	2	262	1	251	8.0e-41	160	COG0451	Nucleoside-diphosphate-sugar epimerase	314
648933248	182	52.91	5	172	30	199	2.0e-52	198	COG1859	RNA:NAD 2'-phosphotransferase, TPT1/KptA family	211
648933249	158	34.19	1	152	1	155	1.0e-33	135	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
648933251	384	25	1	360	1	370	5.0e-33	135	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648933252	253	34.38	8	253	4	244	4.0e-49	188	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
648933254	266	32.32	7	261	31	293	4.0e-41	161	COG0668	Small-conductance mechanosensitive channel	316
648933255	248	35.25	1	240	2	242	4.0e-39	154	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
648933256	863	31.51	13	444	6	423	1.0e-48	188	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
648933260	720	45.47	248	718	104	545	0.0e+00	527	COG2225	Malate synthase	545
648933262	229	35.05	1	97	9	105	6.0e-09	54.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
648933264	115	27.1	1	102	1	105	2.0e-12	64.6	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
648933266	474	30.87	192	473	37	329	1.0e-32	134	COG0642	Signal transduction histidine kinase	336
648933267	242	40.34	6	236	1	228	3.0e-56	211	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648933272	376	33.07	1	372	12	390	5.0e-85	308	COG0019	Diaminopimelate decarboxylase	394
648933275	476	72.32	17	470	6	471	0.0e+00	747	COG5310	Homospermidine synthase	481
648933276	205	29.63	53	187	10	134	6.0e-13	67.7	COG3415	Transposase	138
648933279	607	28.57	369	606	4	214	3.0e-31	130	COG2114	Adenylate cyclase, class 3	227
648933280	526	36.43	17	501	18	531	6.0e-99	354	COG0659	Sulfate permease or related transporter, MFS superfamily	554
648933282	245	24.02	20	240	38	264	7.0e-19	87.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
648933283	192	20.32	1	187	8	194	7.0e-08	50.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648933286	393	36.73	19	384	21	389	1.0e-87	317	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
648933287	342	50	1	330	8	337	6.0e-97	347	COG4448	L-asparaginase II	339
648933288	232	32.65	22	217	11	201	8.0e-31	127	COG0684	Regulator of RNase E activity RraA	210
648933290	273	32.09	13	266	1	267	3.0e-46	178	COG1834	N-Dimethylarginine dimethylaminohydrolase	267
648933295	200	29.31	4	171	1	171	8.0e-19	87.2	COG2039	Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)	207
648933302	333	51.25	8	325	1	317	7.0e-99	353	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
648933304	194	39.06	2	189	14	204	6.0e-46	177	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
648933305	462	27.59	4	461	1	408	2.0e-56	213	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648933306	312	21.31	4	304	14	310	6.0e-19	88.4	COG3965	Predicted Co/Zn/Cd cation transporter, cation efflux family	314
648933307	519	30.86	18	426	3	446	2.0e-35	144	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
648933314	687	32.45	45	477	40	486	3.0e-74	273	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
648933315	722	59.7	27	549	24	548	0.0e+00	727	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
648933316	73	63.01	1	73	1	73	2.0e-21	93.8	COG3655	DNA-binding transcriptional regulator, XRE family	73
648933319	256	23.85	44	256	4	199	7.0e-11	61.2	COG3637	Opacity protein and related surface antigens	199
648933323	220	28.44	1	219	2	225	4.0e-27	114	COG1011	FMN phosphatase YigB, HAD superfamily	229
648933324	285	29.33	6	284	1	281	5.0e-57	214	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
648933325	381	21.24	10	380	22	383	4.0e-09	56.4	COG2814	Predicted arabinose efflux permease, MFS family	394
648933331	233	56.72	35	232	2	201	4.0e-74	271	COG0605	Superoxide dismutase	204
648933332	153	34	4	153	2	146	2.0e-14	72.4	COG3909	Cytochrome c556	147
648933333	304	23.18	151	299	14	148	4.0e-09	55.7	COG2010	Cytochrome c, mono- and diheme variants	150
648933334	564	42.86	19	557	9	516	0.0e+00	471	COG1292	Choline-glycine betaine transporter	537
648933336	528	28.57	8	527	20	551	2.0e-72	266	COG0747	ABC-type transport system, periplasmic component	556
648933337	694	54.55	2	693	1	681	0.0e+00	911	COG1770	Protease II	682
648933338	358	38.83	4	357	2	350	8.0e-68	251	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
648933339	750	24.76	415	717	3	295	1.0e-31	131	COG0668	Small-conductance mechanosensitive channel	316
648933343	145	36.51	1	121	13	137	3.0e-26	110	COG5469	Predicted metal-binding protein	143
648933344	257	46.09	4	242	1	242	8.0e-71	260	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
648933345	311	23.9	3	305	8	309	3.0e-27	116	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
648933346	361	42.26	29	360	4	329	5.0e-52	198	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
648933347	413	21.78	7	382	1	368	4.0e-15	76	COG2807	Cyanate permease	395
648933348	258	25.22	10	123	1	115	4.0e-06	45.8	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
648933349	133	25	6	129	1	123	1.0e-09	55.7	COG3686	Uncharacterized conserved protein, MAPEG superfamily	125
648933352	792	34.13	10	628	2	603	7.0e-105	375	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
648933354	125	44.83	1	116	1	115	4.0e-26	110	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
648933355	529	34.95	24	527	1	501	2.0e-64	240	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
648933356	158	48.1	1	158	1	158	3.0e-37	148	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
648933357	118	48.72	16	93	7	84	2.0e-12	64.8	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
648933358	117	43.4	5	108	3	108	8.0e-20	89.1	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
648933359	138	66.91	1	138	4	142	2.0e-53	201	COG4957	Predicted transcriptional regulator	148
648933360	211	31.73	1	206	2	208	4.0e-15	74.9	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
648933365	144	51.43	1	140	8	144	8.0e-45	172	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
648933370	124	46.49	1	113	1	114	7.0e-23	99.3	COG5447	Uncharacterized protein	115
648933374	186	33.92	13	183	7	177	1.0e-28	119	COG5436	Uncharacterized membrane protein	182
648933375	224	41.03	30	223	2	192	5.0e-37	147	COG5402	Uncharacterized protein	194
648933376	725	41.59	58	702	4	647	0.0e+00	540	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
648933378	161	61.07	8	156	6	152	2.0e-54	204	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
648933380	219	26.21	10	215	1	192	3.0e-07	48.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648933382	526	28.15	22	289	7	257	2.0e-17	84	COG4584	Transposase	278
648933383	263	38.33	13	248	13	251	1.0e-41	163	COG1484	DNA replication protein DnaC	254
648933392	301	29.45	1	160	5	152	3.0e-20	92.7	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
648933396	127	38.05	10	121	11	122	2.0e-15	74.9	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
648933397	228	47.37	1	226	4	228	1.0e-56	212	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
648933398	356	22.32	22	354	3	316	4.0e-22	99.5	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
648933399	392	23.53	76	364	35	288	2.0e-34	140	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
648933401	197	26.8	10	185	4	194	1.0e-15	76.2	COG0778	Nitroreductase	207
648933402	200	32.4	16	194	10	176	2.0e-26	112	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
648933404	384	31.23	1	317	7	323	5.0e-31	128	COG5330	Uncharacterized conserved protein, DUF2336 family	364
648933406	265	28.46	13	261	22	273	5.0e-48	184	COG0061	NAD kinase	281
648933407	245	25.35	1	215	17	222	2.0e-13	69.6	COG3591	V8-like Glu-specific endopeptidase	251
648933408	706	28.98	329	567	93	335	2.0e-31	131	COG0642	Signal transduction histidine kinase	336
648933409	255	38.21	4	249	11	255	1.0e-60	226	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
648933410	397	40.78	211	385	3	181	4.0e-36	145	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
648933411	165	29.38	4	163	2	154	9.0e-22	96.6	COG3915	Uncharacterized protein	155
648933414	302	20.85	32	298	4	265	2.0e-14	73.4	COG0338	Site-specific DNA-adenine methylase	274
648933450	271	36.3	1	266	1	246	2.0e-49	189	COG3926	Lysozyme family protein	252
648933455	240	23.23	1	222	1	246	2.0e-14	72.7	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
648933458	277	34.16	42	277	19	259	2.0e-44	173	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
648933464	396	80.56	1	396	1	394	0.0e+00	692	COG0050	Translation elongation factor EF-Tu, a GTPase	394
648933466	63	36.36	3	57	17	71	2.0e-08	50.8	COG0690	Preprotein translocase subunit SecE	73
648933467	177	57.63	1	176	1	177	5.0e-52	197	COG0250	Transcription antitermination factor NusG	178
648933469	142	61.15	2	140	1	138	2.0e-48	184	COG0080	Ribosomal protein L11	141
648933470	231	65.35	1	227	1	228	3.0e-82	297	COG0081	Ribosomal protein L1	228
648933472	172	39.31	1	171	3	175	6.0e-34	136	COG0244	Ribosomal protein L10	175
648933473	125	68	1	125	2	124	3.0e-23	100	COG0222	Ribosomal protein L7/L12	124
648933476	1401	51.06	21	847	7	805	0.0e+00	894	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
648933478	165	72.22	40	165	4	129	9.0e-50	189	COG0048	Ribosomal protein S12	129
648933479	156	64.86	2	149	1	148	9.0e-58	215	COG0049	Ribosomal protein S7	148
648933480	691	65.13	1	690	1	691	0.0e+00	990	COG0480	Translation elongation factor EF-G, a GTPase	697
648933481	396	80.56	1	396	1	394	0.0e+00	692	COG0050	Translation elongation factor EF-Tu, a GTPase	394
648933482	102	74.51	1	102	1	102	2.0e-39	153	COG0051	Ribosomal protein S10	104
648933483	240	53	2	215	1	217	1.0e-73	269	COG0087	Ribosomal protein L3	218
648933484	206	45.71	1	206	2	211	2.0e-53	202	COG0088	Ribosomal protein L4	214
648933485	97	62.77	6	97	1	94	3.0e-23	99.9	COG0089	Ribosomal protein L23	94
648933486	277	60.22	1	273	1	274	3.0e-109	387	COG0090	Ribosomal protein L2	275
648933487	92	64.52	1	92	1	93	3.0e-36	143	COG0185	Ribosomal protein S19	93
648933488	126	55.75	12	124	8	120	1.0e-29	121	COG0091	Ribosomal protein L22	120
648933489	242	60.52	12	242	1	233	9.0e-79	286	COG0092	Ribosomal protein S3	233
648933490	137	64.96	1	135	2	138	2.0e-50	190	COG0197	Ribosomal protein L16/L10AE	146
648933491	66	58.46	2	66	4	68	5.0e-10	56	COG0255	Ribosomal protein L29	69
648933492	76	56.76	1	74	6	79	2.0e-20	90.3	COG0186	Ribosomal protein S17	87
648933493	122	75.41	1	122	1	122	2.0e-48	184	COG0093	Ribosomal protein L14	122
648933494	105	57.55	1	104	1	104	5.0e-22	95.7	COG0198	Ribosomal protein L24	104
648933495	184	62.57	6	184	1	179	2.0e-75	275	COG0094	Ribosomal protein L5	180
648933496	101	54.1	41	101	1	61	1.0e-14	71	COG0199	Ribosomal protein S14	61
648933497	132	54.14	1	132	1	132	2.0e-45	174	COG0096	Ribosomal protein S8	132
648933498	177	58.52	1	176	1	176	1.0e-62	232	COG0097	Ribosomal protein L6P/L9E	178
648933499	120	55.74	1	120	5	125	3.0e-30	124	COG0256	Ribosomal protein L18	125
648933500	188	59.06	3	173	11	181	5.0e-60	223	COG0098	Ribosomal protein S5	181
648933501	65	49.09	8	62	1	55	4.0e-12	62.8	COG1841	Ribosomal protein L30/L7E	55
648933502	156	52.9	1	152	1	152	3.0e-31	127	COG0200	Ribosomal protein L15	152
648933503	443	53.95	13	434	9	432	1.0e-128	453	COG0201	Preprotein translocase subunit SecY	436
648933504	197	43.23	1	192	1	178	4.0e-47	181	COG0563	Adenylate kinase or related kinase	178
648933506	122	65.29	1	121	1	121	7.0e-42	162	COG0099	Ribosomal protein S13	121
648933507	129	66.67	1	129	1	129	2.0e-49	187	COG0100	Ribosomal protein S11	129
648933508	340	50.79	10	326	1	314	9.0e-99	353	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
648933509	141	67.24	1	116	1	116	1.0e-45	174	COG0203	Ribosomal protein L17	116
648933512	479	43.25	10	371	1	339	1.0e-67	250	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
648933513	437	55.81	11	435	7	436	0.0e+00	609	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
648933515	128	51.59	1	126	2	126	3.0e-19	87.5	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
648933516	333	35.64	8	309	5	289	1.0e-65	243	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
648933522	226	31.51	1	218	4	220	4.0e-37	147	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
648933523	257	45.38	1	255	1	260	2.0e-61	229	COG5387	Chaperone required for the assembly of the mitochondrial F1-ATPase	264
648933525	472	34.59	23	471	3	448	5.0e-82	298	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
648933526	243	54.13	1	242	1	240	1.0e-84	306	COG3484	Predicted proteasome-type protease	255
648933527	271	30.77	1	265	11	306	2.0e-31	129	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
648933528	316	34.18	1	313	1	306	5.0e-66	244	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
648933531	510	58.38	1	510	11	526	0.0e+00	711	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
648933532	596	24.03	210	589	48	408	3.0e-27	117	COG0840	Methyl-accepting chemotaxis protein	408
648933534	123	50	1	120	2	121	4.0e-33	133	COG1539	Dihydroneopterin aldolase	121
648933535	670	56.57	1	670	1	644	0.0e+00	881	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
648933537	163	22.98	1	159	57	217	1.0e-23	102	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
648933538	165	25.97	5	149	3	156	1.0e-13	69.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648933541	311	25.75	2	274	1	293	1.0e-24	106	COG0451	Nucleoside-diphosphate-sugar epimerase	314
648933542	236	51.4	19	232	7	213	3.0e-75	274	COG0321	Lipoate-protein ligase B	221
648933552	243	19.59	1	243	72	307	4.0e-11	61.9	COG0679	Predicted permease	311
648933555	651	43.53	442	610	11	178	1.0e-39	158	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
648933561	164	28.28	7	151	6	149	6.0e-23	100	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648933563	623	26.87	85	418	2	332	8.0e-38	152	COG0642	Signal transduction histidine kinase	336
648933564	387	27.4	24	387	1	365	2.0e-45	176	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648933565	857	22.66	428	855	7	404	4.0e-25	110	COG0840	Methyl-accepting chemotaxis protein	408
648933566	469	41.36	32	469	12	451	8.0e-110	391	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
648933567	152	32.59	17	151	3	137	6.0e-20	90.3	COG3011	Predicted thiol-disulfide oxidoreductase YuxK, DCC family	137
648933568	529	23.42	1	291	2	303	2.0e-21	97.7	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
648933570	330	49.68	2	309	4	295	4.0e-79	288	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
648933571	231	37.8	100	226	1	126	9.0e-14	70.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
648933573	142	28.47	9	132	2	137	3.0e-08	51.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
648933575	236	39.49	39	227	61	255	5.0e-39	154	COG3757	Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family	269
648933576	134	33.87	5	124	1	124	9.0e-13	65.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
648933577	147	25.38	11	140	8	135	1.0e-17	82.4	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
648933579	390	44.56	10	386	2	387	3.0e-96	345	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648933584	126	37.62	7	105	9	109	5.0e-10	56.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
648933588	323	39.35	15	317	1	304	4.0e-62	231	COG0010	Arginase family enzyme	305
648933589	128	28.04	18	124	25	127	7.0e-13	66.2	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
648933590	137	53.33	1	135	1	134	2.0e-34	137	COG3602	Uncharacterized protein	134
648933591	280	31.11	3	175	41	218	1.0e-30	127	COG2114	Adenylate cyclase, class 3	227
648933592	210	43.93	38	209	24	196	2.0e-54	205	COG0740	ATP-dependent protease ClpP, protease subunit	200
648933593	267	28.93	15	256	1	223	3.0e-27	115	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
648933594	246	49.1	13	229	2	223	4.0e-54	204	COG3821	Uncharacterized membrane protein	234
648933596	324	21.02	30	321	1	305	5.0e-17	82.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
648933598	144	61.81	1	144	1	144	4.0e-53	200	COG5458	Uncharacterized protein	144
648933599	281	30.34	6	236	4	231	7.0e-27	114	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648933602	492	32.56	1	343	1	345	3.0e-72	266	COG1686	D-alanyl-D-alanine carboxypeptidase	389
648933606	110	51.02	13	110	10	107	6.0e-33	132	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
648933607	824	46.04	4	753	2	778	0.0e+00	858	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
648933609	319	36.19	5	238	2	256	3.0e-38	152	COG3380	Predicted NAD/FAD-dependent oxidoreductase	331
648933612	236	19.72	20	230	32	233	4.0e-15	75	COG0421	Spermidine synthase	282
648933613	291	28.33	4	289	1	290	2.0e-31	129	COG0583	DNA-binding transcriptional regulator, LysR family	297
648933614	234	33.99	1	231	2	251	3.0e-36	144	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648933615	258	19.82	30	251	13	229	1.0e-07	50.3	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
648933618	142	42.03	8	142	1	138	3.0e-32	130	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
648933619	333	51.64	28	330	1	303	2.0e-125	442	COG1897	Homoserine trans-succinylase	307
648933621	430	56.17	10	422	6	385	0.0e+00	522	COG3146	Predicted N-acyltransferase	387
648933622	252	24.31	9	248	6	248	4.0e-19	88.7	COG0584	Glycerophosphoryl diester phosphodiesterase	257
648933623	154	34.93	8	153	1	128	1.0e-18	86.1	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
648933625	441	47.86	51	394	2	352	2.0e-92	333	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
648933628	125	35.16	1	125	4	129	8.0e-19	86.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
648933629	570	28.76	196	563	57	406	7.0e-28	119	COG0840	Methyl-accepting chemotaxis protein	408
648933630	55	46.81	7	53	4	50	9.0e-07	45.2	COG0267	Ribosomal protein L33	50
648933632	158	53.66	19	141	3	125	9.0e-43	166	COG5349	Uncharacterized conserved protein, DUF983 family	126
648933633	776	39.5	28	739	4	706	0.0e+00	585	COG0557	Exoribonuclease R	706
648933634	905	49.92	1	594	1	569	0.0e+00	633	COG0550	DNA topoisomerase IA	570
648933635	378	38.92	14	377	3	350	2.0e-87	316	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
648933636	220	45.92	14	203	5	200	3.0e-48	185	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
648933640	433	40.65	8	433	2	423	5.0e-109	388	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
648933641	309	50.16	1	302	3	310	2.0e-107	382	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
648933642	309	30.77	1	309	2	309	8.0e-29	121	COG0679	Predicted permease	311
648933643	508	47.01	10	142	8	132	7.0e-33	135	COG3474	Cytochrome c2	135
648933644	203	18.88	11	202	65	312	1.0e-09	56.7	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
648933645	160	48.53	21	155	3	138	4.0e-41	160	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
648933646	235	28.15	1	229	7	242	3.0e-36	145	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
648933649	95	48.42	1	95	1	95	9.0e-22	95.3	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
648933651	494	50.7	1	490	1	473	0.0e+00	504	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
648933652	366	36.19	1	361	1	368	9.0e-80	290	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
648933653	85	61.18	1	85	1	85	3.0e-25	106	COG3811	Uncharacterized protein YjhX, UPF0386 family	85
648933658	99	40.24	7	88	3	84	5.0e-17	79.1	COG2257	Type III secretion system substrate exporter, FlhB-like	92
648933661	505	57.56	29	505	1	483	0.0e+00	693	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
648933664	345	35.29	16	344	12	345	2.0e-59	223	COG2957	Agmatine/peptidylarginine deiminase	346
648933665	237	31.03	11	207	4	200	1.0e-36	146	COG0625	Glutathione S-transferase	211
648933667	139	33.57	1	139	34	162	2.0e-19	88.1	COG4731	Uncharacterized conserved protein, DUF2147 family	162
648933672	526	28.15	22	289	7	257	2.0e-17	84	COG4584	Transposase	278
648933673	263	38.75	13	248	13	251	4.0e-42	165	COG1484	DNA replication protein DnaC	254
648933677	305	31.65	1	156	5	152	3.0e-18	85.8	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
648933686	285	32.02	5	253	4	244	1.0e-42	167	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648933687	477	46.09	5	473	1	465	5.0e-130	457	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648933688	534	35.14	12	530	1	529	2.0e-104	373	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648933689	263	36.76	1	250	5	250	2.0e-40	159	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648933690	499	37.52	13	497	36	533	7.0e-109	387	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648933692	296	25.84	3	296	1	292	4.0e-30	125	COG0583	DNA-binding transcriptional regulator, LysR family	297
648933693	426	32.27	86	413	38	379	2.0e-54	206	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
648933694	294	28.23	5	290	2	294	1.0e-28	120	COG0583	DNA-binding transcriptional regulator, LysR family	297
648933696	342	26.56	14	333	1	318	9.0e-52	197	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
648933697	355	51.58	1	349	1	337	2.0e-117	416	COG3839	ABC-type sugar transport system, ATPase component	338
648933698	1049	30.17	237	1045	203	943	6.0e-112	399	COG0383	Alpha-mannosidase	943
648933699	275	36.3	2	274	1	281	5.0e-43	168	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648933700	297	37.96	21	290	17	285	3.0e-42	165	COG1175	ABC-type sugar transport system, permease component	295
648933701	439	23.11	1	432	6	432	1.0e-28	121	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648933703	472	31.99	1	286	4	293	1.0e-52	200	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
648933704	303	51.84	5	300	1	298	4.0e-99	354	COG3246	Uncharacterized conserved protein, DUF849 family	298
648933705	261	37.64	1	258	2	257	2.0e-48	186	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648933706	677	31.32	1	598	1	593	5.0e-84	306	COG1042	Acyl-CoA synthetase (NDP forming)	598
648933707	386	38.78	1	382	1	388	2.0e-84	306	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648933708	315	40.94	1	313	1	320	2.0e-70	259	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
648933709	215	19.08	1	173	4	175	1.0e-07	50	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648933710	521	47.79	4	521	10	526	0.0e+00	568	COG5598	Trimethylamine:corrinoid methyltransferase	526
648933711	681	35.5	1	364	1	361	7.0e-84	305	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
648933714	208	40.49	2	204	1	204	1.0e-25	109	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
648933716	121	41.23	7	120	3	116	2.0e-28	117	COG1733	DNA-binding transcriptional regulator, HxlR family	120
648933717	510	38.05	1	505	5	544	1.0e-128	453	COG0143	Methionyl-tRNA synthetase	558
648933720	472	19.43	87	426	17	356	2.0e-35	144	COG0641	Sulfatase maturation enzyme AslB, radical SAM superfamily	378
648933721	331	37.35	11	331	14	334	4.0e-57	215	COG2855	Uncharacterized membrane protein YadS	334
648933723	327	30.92	1	326	30	316	1.0e-40	160	COG1858	Cytochrome c peroxidase	364
648933725	352	28.02	1	338	2	332	1.0e-50	193	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648933726	429	54.74	47	426	1	379	3.0e-95	342	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648933727	196	22.41	17	190	11	171	3.0e-11	62.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648933728	171	41.06	20	163	7	157	4.0e-29	121	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
648933729	296	48.84	1	296	1	298	3.0e-98	351	COG4989	Predicted oxidoreductase	298
648933730	384	27.46	42	363	16	334	8.0e-47	181	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
648933731	244	32.07	10	243	2	236	2.0e-33	135	COG2188	DNA-binding transcriptional regulator, GntR family	236
648933732	373	23.18	2	366	1	342	2.0e-29	123	COG0673	Predicted dehydrogenase	342
648933733	425	20.11	35	362	2	323	5.0e-23	102	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
648933734	258	57.55	45	150	25	129	3.0e-36	145	COG3474	Cytochrome c2	135
648933735	366	53.54	2	128	7	132	4.0e-37	149	COG3474	Cytochrome c2	135
648933736	427	28.95	12	273	2	228	2.0e-29	123	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
648933737	565	27.31	38	535	16	471	3.0e-65	243	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
648933740	149	35.62	8	149	11	148	6.0e-12	63.5	COG5501	Predicted secreted protein	148
648933742	195	24.5	31	178	20	162	1.0e-14	73.5	COG2143	Thioredoxin-related protein	182
648933743	244	47.06	3	222	10	220	4.0e-33	135	COG0785	Cytochrome c biogenesis protein CcdA	220
648933745	130	39.13	27	117	10	101	2.0e-07	47.9	COG0640	DNA-binding transcriptional regulator, ArsR family	110
648933747	317	20.76	79	314	12	222	2.0e-12	66.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648933750	508	44.38	89	247	1	157	2.0e-28	120	COG3436	Transposase	157
648933756	153	37.66	1	153	2	154	5.0e-27	113	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648933757	488	29.81	41	462	19	403	2.0e-68	253	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
648933758	259	30.53	1	252	1	250	3.0e-43	169	COG0121	Predicted glutamine amidotransferase	252
648933759	206	29.89	15	190	1	182	7.0e-22	97.4	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
648933760	191	19.05	1	188	8	196	1.0e-10	59.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648933762	215	28.16	10	212	1	197	3.0e-26	111	COG0625	Glutathione S-transferase	211
648933763	279	25.71	80	249	16	190	4.0e-24	105	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
648933765	278	50.78	1	257	3	258	1.0e-89	323	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
648933766	307	34.52	1	307	2	297	4.0e-61	228	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
648933767	283	37.36	7	278	17	283	1.0e-47	183	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
648933768	445	45.89	236	442	77	282	2.0e-57	217	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
648933769	401	38.92	17	329	26	340	2.0e-76	279	COG2951	Membrane-bound lytic murein transglycosylase B	343
648933770	213	24.9	4	213	3	255	2.0e-29	122	COG1192	Cellulose biosynthesis protein BcsQ	259
648933771	1777	34.83	169	1775	46	1621	0.0e+00	947	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
648933772	694	43.63	38	694	35	732	0.0e+00	611	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
648933774	306	21.91	48	290	23	267	1.0e-09	57.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648933776	292	50.34	1	291	4	296	2.0e-94	339	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
648933777	160	61.07	10	158	3	150	1.0e-52	199	COG0691	tmRNA-binding protein	153
648933778	149	29.93	15	149	1	135	6.0e-20	89.9	COG0824	Acyl-CoA thioesterase FadM	137
648933779	387	42.97	5	387	2	377	9.0e-101	360	COG1454	Alcohol dehydrogenase, class IV	377
648933780	752	44.25	11	745	5	741	0.0e+00	784	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
648933781	685	40.28	38	665	20	640	0.0e+00	523	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
648933782	256	31.71	1	238	4	246	2.0e-38	152	COG1381	Recombinational DNA repair protein (RecF pathway)	251
648933783	313	46.64	16	312	1	298	4.0e-106	377	COG1159	GTPase Era, involved in 16S rRNA processing	298
648933784	235	45.3	3	234	1	233	3.0e-66	245	COG0571	dsRNA-specific ribonuclease	235
648933785	250	32.91	16	130	9	166	9.0e-14	70.8	COG0681	Signal peptidase I	166
648933786	144	44.27	1	131	1	127	2.0e-36	144	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
648933787	196	46.45	1	183	1	180	8.0e-44	170	COG3216	Uncharacterized conserved protein, DUF2062 family	184
648933788	193	34.48	1	191	1	201	1.0e-37	149	COG0461	Orotate phosphoribosyltransferase	201
648933789	762	38.58	19	760	6	701	0.0e+00	803	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
648933790	134	54.05	1	72	1	74	3.0e-14	71.1	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
648933791	194	40.86	1	183	1	179	2.0e-38	151	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
648933792	224	26.09	15	221	15	199	2.0e-25	109	COG1573	Uracil-DNA glycosylase	202
648933793	256	54.17	6	245	7	241	6.0e-87	313	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
648933794	620	17.52	112	618	29	456	9.0e-25	108	COG0471	Di- and tricarboxylate transporter	461
648933795	168	27.54	18	154	10	147	6.0e-09	54	COG1714	Uncharacterized membrane protein YckC, RDD family	172
648933798	415	52.17	4	342	2	346	1.0e-98	353	COG1171	Threonine dehydratase	347
648933799	366	58.79	37	365	1	329	0.0e+00	511	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
648933800	379	45.24	1	378	1	388	2.0e-94	339	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648933801	344	26.73	1	317	3	257	1.0e-40	160	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648933803	297	46.08	3	294	1	286	2.0e-76	279	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
648933804	170	27.91	33	160	1	126	4.0e-06	44.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
648933805	437	40.5	8	427	118	549	3.0e-116	412	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
648933811	485	46.09	10	480	1	467	0.0e+00	510	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648933813	1459	21.6	296	1459	155	1278	3.0e-77	284	COG2911	Autotransporter translocation and assembly factor TamB	1278
648933814	630	31.08	14	630	1	594	3.0e-99	356	COG0729	Outer membrane translocation and assembly module TamA	594
648933816	340	55.97	42	334	1	283	3.0e-107	381	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
648933817	391	41.6	9	381	4	376	1.0e-85	309	COG2942	Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family	388
648933819	513	53.5	3	511	12	524	0.0e+00	645	COG5598	Trimethylamine:corrinoid methyltransferase	526
648933820	853	30.28	435	853	2	379	2.0e-77	284	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
648933821	346	35.53	13	299	11	311	4.0e-72	265	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
648933823	677	40.72	10	675	4	614	0.0e+00	601	COG3894	Uncharacterized 2Fe-2 and 4Fe-4S clusters-containing protein, contains DUF4445 domain	614
648933825	294	24.52	31	282	43	290	2.0e-20	93.1	COG0685	5,10-methylenetetrahydrofolate reductase	291
648933828	234	48.21	3	225	4	227	2.0e-67	249	COG5012	Methanogenic corrinoid protein MtbC1	227
648933829	118	29.82	3	116	11	120	1.0e-05	42	COG3293	Transposase	124
648933832	556	69.13	3	556	1	554	0.0e+00	921	COG2759	Formyltetrahydrofolate synthetase	554
648933834	354	35	2	161	1	139	1.0e-21	97.7	COG1056	Nicotinamide mononucleotide adenylyltransferase	172
648933835	467	22.53	1	459	10	405	9.0e-46	178	COG1488	Nicotinic acid phosphoribosyltransferase	405
648933836	410	39.95	13	404	4	386	3.0e-98	352	COG3214	Uncharacterized conserved protein YcaQ, contains winged helix DNA-binding domain	400
648933839	226	46.49	1	226	1	227	2.0e-58	219	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648933840	464	27.85	136	445	5	313	7.0e-27	115	COG0642	Signal transduction histidine kinase	336
648933842	343	43.44	1	320	1	320	8.0e-91	327	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
648933843	270	29.37	14	268	1	266	6.0e-44	171	COG1018	Ferredoxin-NADP reductase	266
648933844	327	29.66	20	309	17	289	5.0e-64	238	COG2089	Sialic acid synthase SpsE, contains C-terminal SAF domain	347
648933845	169	35.48	15	168	7	161	2.0e-31	128	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
648933851	578	20.29	91	507	62	411	8.0e-20	92.3	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
648933852	234	28.45	1	231	1	224	2.0e-30	126	COG1083	CMP-N-acetylneuraminic acid synthetase	228
648933855	222	34.1	1	216	4	218	3.0e-38	152	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
648933856	229	52.19	5	229	6	227	1.0e-70	259	COG0120	Ribose 5-phosphate isomerase	227
648933857	172	32.75	1	171	2	171	2.0e-18	85.5	COG3184	Uncharacterized protein	183
648933858	458	36.95	5	450	4	454	5.0e-117	414	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
648933859	521	39.89	322	501	1	181	2.0e-35	144	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
648933860	397	32.33	11	396	4	401	1.0e-69	257	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
648933864	326	25.39	110	302	58	231	1.0e-11	64.6	COG2801	Transposase InsO and inactivated derivatives	232
648933865	244	25.34	25	242	8	228	4.0e-14	71.9	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
648933867	460	70.47	1	446	1	445	0.0e+00	762	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
648933869	555	42.76	271	544	9	268	2.0e-75	276	COG0171	NH3-dependent NAD+ synthetase	268
648933870	415	19.22	22	403	24	432	4.0e-13	69.8	COG2271	Sugar phosphate permease	448
648933871	454	37.61	2	452	9	466	1.0e-105	377	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
648933873	164	25.66	32	144	1	113	2.0e-12	65.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
648933874	380	19.72	38	244	30	235	4.0e-10	59.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648933875	168	42.95	1	154	1	155	4.0e-41	160	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
648933876	129	34.65	13	112	2	102	7.0e-10	56.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
648933881	477	49.07	20	476	1	464	0.0e+00	572	COG0215	Cysteinyl-tRNA synthetase	464
648933882	167	44.35	10	123	5	119	1.0e-30	125	COG3791	Uncharacterized conserved protein	133
648933883	164	37.59	11	138	1	133	7.0e-28	116	COG3791	Uncharacterized conserved protein	133
648933884	531	36.28	4	431	1	409	4.0e-101	362	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
648933885	315	43.99	17	307	4	293	6.0e-65	241	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
648933886	205	39.78	6	187	11	195	2.0e-40	158	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
648933890	651	64.39	122	617	1	497	0.0e+00	713	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
648933892	316	35.1	1	296	1	297	3.0e-44	172	COG0583	DNA-binding transcriptional regulator, LysR family	297
648933893	234	44.59	1	219	15	236	2.0e-56	212	COG0688	Phosphatidylserine decarboxylase	239
648933894	300	42.86	29	266	4	231	5.0e-50	191	COG1183	Phosphatidylserine synthase	234
648933895	173	40.35	1	164	1	167	2.0e-26	112	COG3153	Predicted N-acetyltransferase YhbS	171
648933896	315	23.01	25	137	10	122	7.0e-09	54.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
648933898	367	26.04	42	356	28	365	2.0e-13	70.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
648933899	183	29.23	2	131	9	137	1.0e-13	69.9	COG1695	DNA-binding transcriptional regulator, PadR family	138
648933902	401	39.56	1	401	1	392	1.0e-89	323	COG0183	Acetyl-CoA acetyltransferase	392
648933903	463	47.75	4	332	2	333	8.0e-113	401	COG0836	Mannose-1-phosphate guanylyltransferase	333
648933904	274	42.35	2	237	1	254	1.0e-70	260	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
648933905	275	42.8	1	257	9	265	2.0e-45	176	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
648933906	137	31.88	1	137	11	145	2.0e-23	101	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
648933908	195	39.88	30	189	1	161	5.0e-41	160	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
648933909	289	22.79	43	288	3	272	4.0e-24	105	COG1082	Sugar phosphate isomerase/epimerase	274
648933910	377	27.86	5	357	4	340	9.0e-46	178	COG0673	Predicted dehydrogenase	342
648933911	193	37.38	1	190	1	213	4.0e-26	111	COG4094	Uncharacterized membrane protein	219
648933913	227	41.82	1	218	2	221	4.0e-44	171	COG4649	Uncharacterized protein	221
648933914	450	26.47	72	338	20	279	8.0e-21	95.3	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
648933915	478	47.11	4	470	5	443	0.0e+00	539	COG1160	Predicted GTPases	444
648933921	241	31.48	4	216	2	214	1.0e-28	120	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648933922	490	52.79	18	477	1	461	0.0e+00	632	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
648933923	205	34.3	3	174	1	171	1.0e-31	129	COG1286	Uncharacterized membrane protein, required for colicin V production	182
648933924	464	52.84	1	455	1	454	0.0e+00	592	COG1066	Predicted ATP-dependent serine protease	456
648933925	400	39.5	37	396	6	358	2.0e-92	333	COG0787	Alanine racemase	360
648933926	502	39.66	24	492	1	434	0.0e+00	470	COG0305	Replicative DNA helicase	435
648933927	195	47.97	1	148	1	148	6.0e-45	173	COG0359	Ribosomal protein L9	148
648933928	82	62.67	3	77	1	75	9.0e-21	91.8	COG0238	Ribosomal protein S18	75
648933929	136	51.82	4	113	3	112	5.0e-32	129	COG0360	Ribosomal protein S6	112
648933930	314	52.9	1	310	2	309	4.0e-91	328	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
648933931	245	45.67	2	243	1	251	4.0e-46	178	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648933932	78	58.97	1	78	3	80	3.0e-13	66.5	COG0236	Acyl carrier protein	80
648933933	429	55.82	9	427	2	411	0.0e+00	495	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
648933934	389	43.43	41	373	2	342	3.0e-95	342	COG1559	Cell division protein YceG, involved in septum cleavage	342
648933935	297	44.59	3	297	2	290	4.0e-76	278	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
648933936	234	52.13	22	209	2	187	3.0e-65	241	COG0194	Guanylate kinase	191
648933937	280	46.36	21	279	4	256	1.0e-76	279	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
648933938	338	44.18	6	338	4	331	7.0e-94	337	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
648933940	772	27.45	6	769	23	768	3.0e-101	363	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
648933941	364	29.97	5	364	2	364	1.0e-41	164	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
648933942	395	23.22	1	362	1	364	3.0e-40	159	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
648933943	501	47.93	20	499	18	485	0.0e+00	484	COG0260	Leucyl aminopeptidase	485
648933945	150	32.41	4	146	3	142	1.0e-32	132	COG2927	DNA polymerase III, chi subunit	144
648933952	637	42.03	11	531	1	529	0.0e+00	520	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
648933953	700	32.34	6	700	38	765	0.0e+00	471	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
648933957	140	61.48	2	136	1	135	2.0e-54	204	COG0105	Nucleoside diphosphate kinase	135
648933960	222	50.75	5	205	1	200	3.0e-68	251	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
648933961	363	57.35	14	360	1	345	2.0e-129	456	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
648933963	361	33.91	1	348	10	349	5.0e-41	161	COG0628	Predicted PurR-regulated permease PerM	355
648933965	739	54.56	29	725	1	696	0.0e+00	956	COG0855	Polyphosphate kinase	696
648933966	497	30.32	6	469	4	473	5.0e-96	345	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
648933968	330	44.15	1	298	66	361	2.0e-86	312	COG0349	Ribonuclease D	361
648933969	208	26.38	1	189	2	235	1.0e-16	79.9	COG1192	Cellulose biosynthesis protein BcsQ	259
648933970	238	46.29	10	238	2	229	2.0e-58	219	COG1346	Putative effector of murein hydrolase	230
648933971	120	37.5	1	120	7	126	1.0e-16	78.6	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
648933972	603	49.49	13	597	1	582	0.0e+00	802	COG0173	Aspartyl-tRNA synthetase	585
648933973	596	38.53	21	589	1	567	5.0e-126	445	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
648933974	250	42.11	73	235	11	180	3.0e-36	145	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
648933978	302	26.64	4	286	3	303	1.0e-28	121	COG0524	Sugar or nucleoside kinase, ribokinase family	311
648933979	521	36.03	245	491	6	251	5.0e-65	242	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
648933980	165	46.3	2	162	1	162	4.0e-48	183	COG3194	Ureidoglycolate hydrolase (allantoin degradation)	168
648933981	273	63.3	6	272	3	263	4.0e-115	407	COG3257	Uncharacterized protein, possibly involved in glyoxylate utilization	264
648933984	313	31	5	302	1	295	6.0e-35	141	COG0583	DNA-binding transcriptional regulator, LysR family	297
648933987	493	45.16	1	493	1	488	0.0e+00	554	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
648933990	168	47.06	1	164	5	174	1.0e-61	228	COG0225	Peptide methionine sulfoxide reductase MsrA	174
648933991	147	67.65	1	136	1	136	9.0e-61	225	COG0229	Peptide methionine sulfoxide reductase MsrB	140
648933994	537	40	336	515	5	181	3.0e-37	150	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
648933995	173	51.45	3	140	1	136	1.0e-44	172	COG1832	Predicted CoA-binding protein	140
648933996	277	34.47	13	274	1	257	4.0e-49	188	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648933997	141	34.04	1	141	1	139	2.0e-22	98.6	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
648934001	156	60.81	1	148	1	148	5.0e-56	210	COG0102	Ribosomal protein L13	148
648934002	158	56.59	30	158	2	130	8.0e-47	179	COG0103	Ribosomal protein S9	130
648934003	205	29.63	53	187	10	134	6.0e-13	67.7	COG3415	Transposase	138
648934006	708	36.17	1	360	12	386	3.0e-53	203	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
648934007	681	35.75	1	357	12	382	2.0e-52	200	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
648934008	141	29.63	4	105	1	108	2.0e-10	58.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
648934010	436	31.13	32	433	20	418	2.0e-81	296	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
648934012	321	37.13	25	316	1	305	2.0e-60	226	COG0010	Arginase family enzyme	305
648934015	600	56.17	143	596	1	443	0.0e+00	586	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
648934017	405	40.15	8	390	5	391	2.0e-99	356	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
648934018	437	53.05	3	322	2	329	7.0e-101	361	COG0460	Homoserine dehydrogenase	333
648934019	331	56.33	12	330	1	329	2.0e-113	402	COG1494	Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase or related protein	332
648934020	606	39.33	70	578	6	491	3.0e-103	369	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
648934023	296	24.88	3	216	2	207	1.0e-19	90.6	COG0388	Predicted amidohydrolase	274
648934025	510	29.28	64	507	1	325	7.0e-46	178	COG0306	Phosphate/sulfate permease	326
648934027	497	33.03	58	496	3	326	3.0e-50	193	COG0306	Phosphate/sulfate permease	326
648934028	219	51.42	2	213	64	273	2.0e-69	255	COG2998	ABC-type tungstate transport system, permease component	280
648934030	235	40.91	7	226	6	225	1.0e-40	159	COG4662	ABC-type tungstate transport system, periplasmic component	227
648934031	191	34.71	23	190	24	189	5.0e-31	127	COG4583	Sarcosine oxidase gamma subunit	189
648934032	101	56.12	1	98	1	97	3.0e-36	143	COG4311	Sarcosine oxidase delta subunit	97
648934033	417	29.04	29	407	1	387	3.0e-56	212	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648934038	255	28.71	53	252	12	207	8.0e-15	74.3	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
648934039	392	33.91	51	385	53	363	9.0e-52	197	COG1858	Cytochrome c peroxidase	364
648934042	222	59.52	1	210	4	207	1.0e-77	282	COG2945	Alpha/beta superfamily hydrolase	210
648934044	386	46.48	5	382	3	383	4.0e-113	401	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
648934045	490	42.16	40	488	1	412	1.0e-123	437	COG0719	Fe-S cluster assembly scaffold protein SufB	412
648934048	250	61.29	1	248	3	245	1.0e-100	359	COG0396	Fe-S cluster assembly ATPase SufC	251
648934049	440	26.71	16	435	1	410	9.0e-59	221	COG0719	Fe-S cluster assembly scaffold protein SufB	412
648934052	132	45.95	23	132	1	111	2.0e-29	121	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
648934053	122	45.87	4	112	2	110	2.0e-34	138	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
648934054	219	36.07	1	218	1	217	3.0e-49	188	COG0819	Thiaminase	218
648934056	471	42.08	1	454	29	486	3.0e-113	402	COG0513	Superfamily II DNA and RNA helicase	513
648934057	682	50.7	42	682	5	635	0.0e+00	827	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
648934060	266	27.73	32	245	80	284	9.0e-11	60.8	COG0790	TPR repeat	292
648934062	323	18.15	14	323	17	330	2.0e-15	77	COG0618	nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs	332
648934063	260	48.11	1	259	1	260	1.0e-86	312	COG0708	Exonuclease III	261
648934064	113	43.52	7	113	3	110	8.0e-35	138	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
648934065	405	45.3	4	401	2	412	6.0e-110	391	COG0232	dGTP triphosphohydrolase	412
648934066	589	37.38	1	588	1	577	0.0e+00	537	COG0018	Arginyl-tRNA synthetase	577
648934069	339	36.98	3	334	6	334	1.0e-64	240	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
648934070	270	35.63	23	267	1	244	2.0e-44	172	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
648934071	232	49.14	28	198	11	184	2.0e-42	165	COG1386	Chromosome segregation and condensation protein ScpB	184
648934072	379	39.32	36	377	6	352	2.0e-97	349	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
648934073	79	26.92	1	78	2	79	1.0e-09	55	COG1826	Sec-independent protein translocase protein TatA	94
648934074	144	27.37	1	95	1	93	4.0e-11	60.7	COG1826	Sec-independent protein translocase protein TatA	94
648934075	265	47.69	4	263	1	255	2.0e-62	232	COG0805	Sec-independent protein secretion pathway component TatC	255
648934076	425	57.88	1	422	1	423	0.0e+00	576	COG0172	Seryl-tRNA synthetase	429
648934077	252	49.21	1	252	1	252	5.0e-79	287	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
648934078	229	39.22	23	226	3	206	6.0e-46	177	COG2518	Protein-L-isoaspartate O-methyltransferase	209
648934080	304	55.67	22	302	6	283	3.0e-110	391	COG2607	Predicted ATPase, AAA+ superfamily	287
648934082	111	46.39	12	108	1	96	4.0e-24	103	COG1862	Preprotein translocase subunit YajC	97
648934083	536	49.81	1	536	1	506	0.0e+00	497	COG0342	Preprotein translocase subunit SecD	506
648934084	319	49.49	4	296	1	292	8.0e-85	307	COG0341	Preprotein translocase subunit SecF	305
648934087	283	28.47	1	279	6	286	2.0e-39	156	COG1562	Phytoene/squalene synthetase	288
648934088	470	56.47	2	464	4	439	0.0e+00	668	COG1206	Folate-dependent tRNA-U54 methylase TrmFO/GidA	439
648934091	977	69.8	22	967	6	935	0.0e+00	1594	COG0178	Excinuclease UvrABC ATPase subunit	935
648934092	187	37.3	3	187	1	167	6.0e-32	130	COG0629	Single-stranded DNA-binding protein	167
648934093	681	33.15	153	680	61	561	3.0e-116	413	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
648934094	441	39.44	85	439	3	318	6.0e-88	318	COG4531	ABC-type Zn2+ transport system, periplasmic component/surface adhesin	318
648934095	279	34.81	8	279	2	286	1.0e-53	203	COG3327	DNA-binding transcriptional regulator PaaX (phenylacetic acid degradation)	291
648934096	373	46.44	74	339	1	265	8.0e-94	337	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
648934097	94	62.38	4	94	9	109	2.0e-31	127	COG3460	1,2-phenylacetyl-CoA epoxidase, PaaB subunit	117
648934098	258	42.45	17	258	24	265	3.0e-65	242	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
648934099	170	40.4	2	97	11	108	2.0e-19	88.8	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
648934100	358	27.8	1	294	2	265	3.0e-49	189	COG1018	Ferredoxin-NADP reductase	266
648934101	708	27.18	30	528	4	472	8.0e-62	232	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648934102	199	24.48	1	191	2	190	1.0e-11	63.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648934103	437	57.18	14	435	15	437	0.0e+00	523	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
648934104	151	26.87	11	140	1	133	3.0e-19	87.8	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
648934105	263	41	1	260	1	257	8.0e-55	207	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648934106	257	39.76	3	256	1	254	7.0e-49	187	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
648934107	255	43.9	3	248	4	248	3.0e-76	278	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
648934108	339	22.7	1	339	1	329	1.0e-21	97.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
648934111	132	35.16	5	130	7	128	7.0e-19	86.5	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
648934112	403	50.77	10	392	19	406	5.0e-122	431	COG3844	Kynureninase	407
648934113	279	62.69	20	279	3	262	2.0e-98	351	COG3483	Tryptophan 2,3-dioxygenase (vermilion)	262
648934114	538	33.33	29	536	1	518	3.0e-108	386	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
648934115	387	41.65	12	386	5	392	9.0e-69	254	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648934116	268	35.83	13	265	10	257	2.0e-46	179	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648934117	156	28.93	24	144	1	120	1.0e-11	63	COG1846	DNA-binding transcriptional regulator, MarR family	126
648934118	246	33.98	1	244	2	249	2.0e-39	156	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648934119	765	42.78	395	748	4	352	9.0e-103	368	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
648934120	272	18.38	7	252	15	286	1.0e-09	57.2	COG0657	Acetyl esterase/lipase	312
648934121	549	25.05	1	474	5	441	2.0e-56	214	COG3119	Arylsulfatase A or related enzyme	475
648934123	471	30.17	10	471	1	449	2.0e-73	270	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
648934125	388	30.56	7	388	13	407	1.0e-60	227	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648934126	394	32.48	5	394	2	384	1.0e-77	283	COG0006	Xaa-Pro aminopeptidase	384
648934127	339	41.72	1	332	1	336	5.0e-84	304	COG1171	Threonine dehydratase	347
648934128	331	38.34	5	329	4	327	5.0e-78	284	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
648934129	166	36.6	1	153	3	154	1.0e-28	119	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648934130	494	43.43	26	494	4	470	0.0e+00	460	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648934131	457	40.57	4	456	2	446	0.0e+00	495	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
648934134	840	46.66	71	816	1	713	0.0e+00	709	COG2217	Cation transport ATPase	713
648934135	128	30.17	1	114	1	116	1.0e-20	91.7	COG0789	DNA-binding transcriptional regulator, MerR family	124
648934136	158	32.8	14	138	1	125	2.0e-09	55.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
648934137	591	32.65	1	584	1	536	1.0e-112	400	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
648934138	594	23.72	276	571	1	301	2.0e-30	127	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
648934140	421	21.5	1	408	5	426	5.0e-28	118	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648934141	691	25.49	299	547	93	328	4.0e-26	113	COG0642	Signal transduction histidine kinase	336
648934143	400	31.44	10	352	3	350	2.0e-80	292	COG1363	Putative aminopeptidase FrvX	355
648934144	253	30.83	11	247	4	236	4.0e-28	118	COG2186	DNA-binding transcriptional regulator, FadR family	241
648934146	650	50.94	323	639	1	315	2.0e-113	403	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
648934147	314	50.96	1	314	1	314	3.0e-90	325	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648934148	521	34.44	4	517	16	550	2.0e-92	333	COG0747	ABC-type transport system, periplasmic component	556
648934151	507	40.43	12	505	22	532	2.0e-113	403	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648934153	438	36.32	52	431	1	376	2.0e-77	283	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648934154	182	24.84	16	176	4	161	2.0e-14	72.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648934155	328	25.38	3	327	7	329	2.0e-40	159	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648934156	220	38.6	7	220	17	230	5.0e-30	124	COG1802	DNA-binding transcriptional regulator, GntR family	230
648934157	309	29.97	7	300	1	291	8.0e-34	137	COG0583	DNA-binding transcriptional regulator, LysR family	297
648934158	335	45.63	12	316	17	322	2.0e-96	346	COG0158	Fructose-1,6-bisphosphatase	326
648934159	290	51.38	1	290	1	289	9.0e-118	416	COG3954	Phosphoribulokinase	289
648934160	669	55.27	8	662	3	663	0.0e+00	888	COG0021	Transketolase	663
648934161	333	59.04	2	330	1	331	2.0e-128	452	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
648934162	404	46.87	3	397	1	390	8.0e-129	453	COG0126	3-phosphoglycerate kinase	395
648934163	359	42.42	1	329	1	286	6.0e-89	321	COG0191	Fructose/tagatose bisphosphate aldolase	286
648934164	477	49.89	11	465	1	429	0.0e+00	547	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
648934165	119	32.04	14	116	5	107	2.0e-23	100	COG4451	Ribulose bisphosphate carboxylase small subunit	127
648934168	233	56.44	5	228	2	220	4.0e-81	294	COG0036	Pentose-5-phosphate-3-epimerase	220
648934169	383	43.67	8	378	1	365	2.0e-107	382	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
648934170	220	36.99	1	214	3	219	1.0e-33	136	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
648934176	558	65.7	5	558	1	554	0.0e+00	890	COG2759	Formyltetrahydrofolate synthetase	554
648934177	299	50.87	5	291	2	282	2.0e-99	355	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
648934178	310	41.9	24	303	1	280	1.0e-78	286	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
648934179	132	35.77	3	125	8	125	1.0e-16	79.2	COG2346	Truncated hemoglobin YjbI	133
648934184	315	27.15	12	308	1	296	2.0e-30	126	COG0583	DNA-binding transcriptional regulator, LysR family	297
648934185	316	21.47	5	312	9	294	1.0e-25	110	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
648934186	342	57.86	8	286	5	284	4.0e-103	368	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
648934187	660	34.16	55	335	12	280	1.0e-52	201	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
648934189	789	36.32	404	787	1	379	1.0e-93	337	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
648934190	326	25.39	110	302	58	231	9.0e-12	64.6	COG2801	Transposase InsO and inactivated derivatives	232
648934193	325	41.42	16	324	1	280	9.0e-63	234	COG2301	Citrate lyase beta subunit	283
648934194	216	30.39	11	204	1	204	3.0e-32	132	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
648934195	414	25.56	19	408	10	381	1.0e-41	164	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
648934196	398	57.58	1	387	1	386	0.0e+00	513	COG0045	Succinyl-CoA synthetase, beta subunit	387
648934197	292	60.07	1	292	1	289	5.0e-108	384	COG0074	Succinyl-CoA synthetase, alpha subunit	293
648934198	323	41.9	2	323	1	322	4.0e-88	317	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
648934199	878	34.77	33	878	51	910	0.0e+00	542	COG2352	Phosphoenolpyruvate carboxylase	910
648934200	431	65.56	9	429	1	413	0.0e+00	664	COG0112	Glycine/serine hydroxymethyltransferase	413
648934201	326	25.39	110	302	58	231	9.0e-12	64.6	COG2801	Transposase InsO and inactivated derivatives	232
648934205	442	37.17	4	442	5	443	2.0e-117	416	COG0174	Glutamine synthetase	443
648934206	456	34.39	18	427	54	478	4.0e-103	368	COG0069	Glutamate synthase domain 2	485
648934208	225	25.96	26	225	56	289	1.0e-30	126	COG0070	Glutamate synthase domain 3	301
648934209	309	21.21	1	298	12	368	4.0e-48	185	COG0067	Glutamate synthase domain 1	371
648934211	361	28.53	10	338	95	400	5.0e-34	138	COG0004	Ammonia channel protein AmtB	409
648934212	381	33.16	1	379	1	379	1.0e-74	273	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
648934214	328	35.21	12	265	3	266	2.0e-50	193	COG1018	Ferredoxin-NADP reductase	266
648934216	207	32.14	23	105	2	85	1.0e-06	46.9	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
648934217	329	32.05	5	314	13	321	4.0e-61	228	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
648934218	186	25.5	35	181	38	183	6.0e-12	64.2	COG4583	Sarcosine oxidase gamma subunit	189
648934219	983	36.34	587	983	1	379	3.0e-93	337	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
648934220	95	42.55	1	94	2	94	4.0e-19	86.2	COG4311	Sarcosine oxidase delta subunit	97
648934221	416	31.14	28	404	1	387	1.0e-49	190	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648934222	294	27.99	8	293	6	296	2.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
648934223	482	46.12	7	481	3	472	3.0e-125	442	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648934224	342	25.4	24	328	33	313	7.0e-49	188	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
648934228	332	38.35	1	332	3	340	1.0e-82	299	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
648934234	508	44.38	89	247	1	157	2.0e-28	120	COG3436	Transposase	157
648934236	331	24.37	1	310	3	308	1.0e-33	137	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
648934241	653	63.02	10	653	1	649	0.0e+00	828	COG2766	Predicted Ser/Thr protein kinase	649
648934242	440	47.26	1	437	1	422	1.0e-128	453	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
648934243	501	52.9	18	499	9	477	0.0e+00	564	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
648934250	84	47.5	1	78	3	81	9.0e-12	61.9	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
648934253	470	21.47	174	460	6	297	7.0e-20	92.3	COG0863	DNA modification methylase	302
648934255	564	29.98	1	552	4	544	3.0e-84	306	COG2831	Hemolysin activation/secretion protein	554
648934261	364	42.01	34	348	5	314	4.0e-69	255	COG2826	Transposase and inactivated derivatives, IS30 family	318
648934263	640	28.37	267	625	9	335	1.0e-57	217	COG3472	Uncharacterized protein	342
648934269	406	26.1	5	275	7	260	1.0e-16	81.3	COG4584	Transposase	278
648934271	259	34.39	8	256	8	253	7.0e-40	157	COG1484	DNA replication protein DnaC	254
648934276	603	34.45	5	212	2	191	4.0e-28	119	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
648934281	231	53.4	26	231	3	205	7.0e-71	260	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
648934282	500	31.22	268	488	1	170	8.0e-34	138	COG0516	IMP dehydrogenase/GMP reductase	170
648934283	430	36.54	125	429	53	354	5.0e-68	252	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
648934286	516	68.97	198	516	1	315	0.0e+00	550	COG0519	GMP synthase, PP-ATPase domain/subunit	315
648934296	116	33.03	3	110	6	111	3.0e-11	60.8	COG1734	RNA polymerase-binding transcription factor DksA	120
648934298	212	39.62	1	212	3	202	7.0e-34	137	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
648934299	925	53.05	14	896	5	804	0.0e+00	1017	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
648934300	166	51.53	1	163	1	157	3.0e-54	204	COG0669	Phosphopantetheine adenylyltransferase	159
648934301	179	43.4	31	176	1	158	6.0e-45	173	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
648934302	157	49.37	10	154	1	158	3.0e-46	177	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
648934303	357	50.84	1	355	1	347	2.0e-130	458	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
648934304	383	55.14	10	379	1	366	0.0e+00	517	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
648934307	508	44.38	89	247	1	157	2.0e-28	120	COG3436	Transposase	157
648934315	298	55.52	7	296	1	289	1.0e-120	426	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
648934317	280	69.26	7	276	4	273	3.0e-126	444	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
648934318	424	68.63	1	424	1	422	0.0e+00	656	COG0148	Enolase	423
648934319	220	41.4	6	218	5	219	4.0e-52	197	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
648934321	541	23.6	13	529	3	521	1.0e-27	118	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648934322	598	26.58	18	594	27	555	1.0e-71	264	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
648934324	202	30.17	1	166	1	178	2.0e-22	99.3	COG5342	Invasion protein IalB, involved in pathogenesis	181
648934325	119	67.65	13	114	10	111	8.0e-39	152	COG3785	Heat shock protein HspQ	116
648934326	346	31.63	29	337	1	282	2.0e-58	219	COG2301	Citrate lyase beta subunit	283
648934327	296	27.65	9	295	9	296	4.0e-47	181	COG1560	Lauroyl/myristoyl acyltransferase	308
648934328	314	27.07	1	313	2	311	3.0e-31	129	COG0679	Predicted permease	311
648934329	424	31.7	29	409	1	381	1.0e-65	244	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
648934330	301	30.25	15	292	13	278	1.0e-28	120	COG5486	Predicted metal-binding membrane protein	283
648934332	238	25.22	15	238	9	234	1.0e-25	109	COG1183	Phosphatidylserine synthase	234
648934333	325	46.01	4	325	3	326	2.0e-76	279	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
648934334	320	31.99	18	312	5	296	2.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
648934335	116	62.39	1	116	8	124	2.0e-45	174	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
648934336	506	53.35	2	489	6	483	0.0e+00	536	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
648934337	786	61.44	14	776	17	779	0.0e+00	1059	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
648934338	328	29.87	11	306	11	256	9.0e-34	137	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
648934339	522	47.41	18	513	3	501	0.0e+00	579	COG3845	ABC-type uncharacterized transport system, ATPase component	501
648934340	364	44.66	3	356	1	356	4.0e-82	298	COG4603	ABC-type uncharacterized transport system, permease component	356
648934341	304	49.34	1	304	6	304	9.0e-74	270	COG1079	ABC-type uncharacterized transport system, permease component	304
648934342	354	34.82	1	326	11	344	3.0e-78	285	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
648934343	633	29.86	159	633	167	650	2.0e-68	253	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
648934344	485	30.56	225	474	1	251	2.0e-44	173	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
648934345	480	29.82	1	468	1	486	1.0e-95	343	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
648934346	636	36.31	18	634	17	633	0.0e+00	469	COG3525	N-acetyl-beta-hexosaminidase	732
648934347	262	34.54	7	246	4	251	4.0e-33	135	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648934348	288	39.29	1	278	2	280	4.0e-50	191	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
648934349	127	34.62	2	127	1	130	1.0e-27	115	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
648934352	494	48.37	5	491	2	487	0.0e+00	524	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
648934353	355	38.4	1	350	7	368	2.0e-81	296	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
648934354	375	52.96	1	355	1	338	8.0e-121	427	COG3839	ABC-type sugar transport system, ATPase component	338
648934355	403	28.1	1	401	5	428	5.0e-42	165	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648934356	280	40.22	6	279	7	281	1.0e-52	200	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648934357	298	40.07	8	292	8	293	6.0e-56	211	COG1175	ABC-type sugar transport system, permease component	295
648934358	388	23.22	1	377	4	342	7.0e-34	138	COG0673	Predicted dehydrogenase	342
648934359	248	44.81	4	242	2	241	6.0e-64	237	COG3142	Copper homeostasis protein CutC	241
648934360	301	28.53	1	295	7	307	1.0e-35	144	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
648934361	301	37.63	1	295	1	295	4.0e-69	255	COG2103	N-acetylmuramic acid 6-phosphate (MurNAc-6-P) etherase	298
648934362	255	42.62	15	248	2	236	1.0e-52	200	COG2188	DNA-binding transcriptional regulator, GntR family	236
648934363	346	37.94	10	345	2	340	2.0e-71	262	COG2222	Fructoselysine-6-P-deglycase FrlB and related proteins with duplicated sugar isomerase (SIS) domain	340
648934364	392	42.78	6	392	2	379	2.0e-101	363	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
648934365	402	17.21	1	402	7	429	4.0e-12	66.2	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648934368	420	61.12	3	411	1	405	0.0e+00	503	COG3748	Uncharacterized membrane protein	407
648934369	317	29.93	4	301	3	297	1.0e-38	153	COG0583	DNA-binding transcriptional regulator, LysR family	297
648934370	488	57.23	316	488	3	172	4.0e-60	225	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
648934371	327	42.81	5	324	6	330	4.0e-85	308	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
648934374	265	21.03	24	251	4	221	2.0e-09	56.9	COG2801	Transposase InsO and inactivated derivatives	232
648934391	255	50.55	28	116	11	101	1.0e-22	100	COG3561	Phage anti-repressor protein	110
648934395	316	32.38	1	308	5	314	2.0e-59	222	COG1171	Threonine dehydratase	347
648934396	508	44.38	89	247	1	157	2.0e-28	120	COG3436	Transposase	157
648934402	220	39.58	8	199	2	190	2.0e-49	189	COG2518	Protein-L-isoaspartate O-methyltransferase	209
648934403	461	27.19	4	439	13	457	1.0e-41	164	COG1538	Outer membrane protein TolC	457
648934404	305	22.79	14	305	1	229	4.0e-07	48.9	COG3827	Cell pole-organizing protein PopZ	231
648934405	166	46.67	24	157	1	135	7.0e-33	133	COG3543	Uncharacterized protein	135
648934406	977	45.98	2	975	1	877	0.0e+00	1038	COG0525	Valyl-tRNA synthetase	877
648934407	180	60.16	19	140	38	160	1.0e-43	169	COG4765	Uncharacterized protein	164
648934410	235	45.73	10	207	21	217	9.0e-70	256	COG2360	Leu/Phe-tRNA-protein transferase	221
648934412	448	65.92	1	447	1	449	0.0e+00	622	COG0439	Biotin carboxylase	449
648934413	156	40.41	13	156	1	139	1.0e-23	102	COG0511	Biotin carboxyl carrier protein	140
648934415	257	26.94	9	246	2	239	5.0e-25	108	COG1651	Protein-disulfide isomerase	244
648934416	510	31.19	72	506	52	474	2.0e-77	283	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
648934417	389	34.79	14	388	4	389	4.0e-83	301	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
648934419	736	46.43	259	677	69	487	9.0e-118	418	COG1530	Ribonuclease G or E	487
648934420	601	51.99	1	600	25	608	0.0e+00	785	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
648934443	210	31.84	2	202	43	225	7.0e-17	80.8	COG2801	Transposase InsO and inactivated derivatives	232
648934444	188	37.37	1	181	2	199	7.0e-25	107	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
648934451	106	30.3	1	99	1	98	2.0e-11	60.4	COG3668	Plasmid stabilization system protein ParE	98
648934455	110	31.4	20	100	18	98	7.0e-09	52.2	COG5489	Uncharacterized conserved protein, DUF736 family	107
648934458	374	23.88	55	341	35	303	3.0e-21	96.5	COG3547	Transposase	303
648934462	340	35.26	23	333	49	330	2.0e-60	225	COG4962	Pilus assembly protein, ATPase of CpaF family	355
648934463	403	31.96	8	390	4	360	2.0e-48	186	COG2948	Type IV secretory pathway, VirB10 components	360
648934464	271	30.99	5	243	10	240	1.0e-33	137	COG3504	Type IV secretory pathway, VirB9 components	265
648934465	230	33.03	8	224	18	234	6.0e-41	160	COG3736	Type IV secretory pathway, component VirB8	239
648934466	338	17.61	9	307	51	359	1.0e-15	77.7	COG3704	Type IV secretory pathway, VirB6 components	406
648934470	819	36.6	11	812	7	787	0.0e+00	598	COG3451	Type IV secretory pathway, VirB4 component	796
648934471	99	31.82	12	99	8	95	1.0e-13	68.4	COG3702	Type IV secretory pathway, VirB3 components	105
648934472	110	38.96	34	110	29	105	1.0e-08	51.4	COG3838	Type IV secretory pathway, VirB2 components (pilins)	108
648934475	182	24.38	6	159	18	171	3.0e-10	58.7	COG1525	Endonuclease YncB, thermonuclease family	192
648934476	234	24.73	21	198	17	186	8.0e-13	67.6	COG1525	Endonuclease YncB, thermonuclease family	192
648934480	456	14.85	49	443	39	438	4.0e-18	86.3	COG0612	Predicted Zn-dependent peptidase	438
648934483	441	22.63	156	420	91	341	2.0e-14	74.2	COG1566	Multidrug resistance efflux pump	352
648934486	150	32.81	11	137	21	147	2.0e-22	98.4	COG2994	ACP:hemolysin acyltransferase (hemolysin-activating protein)	148
648934491	271	35.37	19	262	76	303	8.0e-28	117	COG3547	Transposase	303
648934493	205	29.63	53	187	10	134	6.0e-13	67.7	COG3415	Transposase	138
648934497	416	23.04	24	416	28	440	6.0e-54	205	COG2067	Long-chain fatty acid transport protein	440
648934499	175	26.52	44	173	1	132	9.0e-12	63.1	COG3335	Transposase	132
648934501	194	25	60	194	3	133	1.0e-15	76.2	COG3791	Uncharacterized conserved protein	133
648934502	115	23.68	2	108	1	110	3.0e-09	54	COG3293	Transposase	124
648934505	394	31.02	113	384	1	258	5.0e-45	175	COG1192	Cellulose biosynthesis protein BcsQ	259
648934506	315	24.67	41	256	1	221	5.0e-16	78.8	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
648934508	298	34.53	7	218	2	222	2.0e-29	122	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
648934509	137	28	8	128	2	126	2.0e-15	74.6	COG5611	Predicted nucleic-acid-binding protein, contains PIN domain	130
648934514	234	29.28	36	199	12	190	1.0e-17	83.8	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
648934517	509	26.77	5	272	7	257	2.0e-17	84	COG4584	Transposase	278
648934518	263	38.33	13	248	13	251	1.0e-41	163	COG1484	DNA replication protein DnaC	254
648934520	422	21.23	46	379	11	358	3.0e-13	70.1	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
648934521	115	39.62	27	79	5	57	1.0e-06	45.2	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
648934522	250	43.22	18	216	4	194	2.0e-42	166	COG3316	Transposase (or an inactivated derivative)	215
648934526	592	50.26	1	575	7	577	0.0e+00	652	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
648934528	82	31.43	11	80	3	67	5.0e-09	52.6	COG3831	WGR domain, predicted DNA-binding domain in MolR	85
648934533	219	37.44	31	219	2	204	5.0e-31	127	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
648934545	343	29.79	5	328	1	303	1.0e-33	137	COG3547	Transposase	303
648934554	370	27.16	73	369	1	310	5.0e-31	128	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
648934555	349	46.18	1	348	3	352	2.0e-102	365	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
648934556	284	27.8	3	277	10	280	8.0e-32	131	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
648934557	275	31.78	9	266	11	262	4.0e-37	148	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
648934558	368	23.24	4	325	2	334	2.0e-31	130	COG4134	ABC-type uncharacterized transport system YnjBCD, periplasmic component	384
648934559	300	28.99	65	270	27	232	2.0e-26	113	COG5255	Uncharacterized protein	239
648934561	253	49.77	14	230	1	207	6.0e-52	197	COG3316	Transposase (or an inactivated derivative)	215
648934563	343	29.79	5	328	1	303	1.0e-33	137	COG3547	Transposase	303
648934566	408	25.88	10	371	30	369	2.0e-44	173	COG1373	Predicted ATPase, AAA+ superfamily	398
648934567	263	43.22	31	229	4	194	2.0e-42	166	COG3316	Transposase (or an inactivated derivative)	215
648934571	332	47.06	7	323	1	323	2.0e-97	349	COG0523	GTPase, G3E family	323
648934572	389	34.75	4	354	1	321	9.0e-64	237	COG0523	GTPase, G3E family	323
648934573	139	30.83	21	139	26	142	1.0e-20	92.7	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
648934574	258	38.19	1	246	1	254	2.0e-71	262	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
648934575	290	39.85	7	276	4	270	1.0e-38	153	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
648934579	229	52.63	36	223	8	195	7.0e-69	253	COG0302	GTP cyclohydrolase I	195
648934580	158	56.88	15	123	2	110	6.0e-40	156	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
648934582	236	43.4	10	221	4	215	7.0e-47	180	COG3316	Transposase (or an inactivated derivative)	215
648934583	123	45.22	5	119	13	127	4.0e-22	97	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
648934584	353	45.61	4	353	1	352	7.0e-110	390	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
648934585	722	31.52	147	713	1	540	2.0e-85	310	COG1178	ABC-type Fe3+ transport system, permease component	540
648934586	347	33.44	46	342	1	297	2.0e-46	179	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
648934587	242	36.55	4	237	1	229	7.0e-45	173	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648934591	263	38.33	13	248	13	251	6.0e-41	161	COG1484	DNA replication protein DnaC	254
648934597	645	27.72	15	196	4	177	1.0e-13	71.9	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
648934602	110	31.4	20	100	18	98	4.0e-09	53	COG5489	Uncharacterized conserved protein, DUF736 family	107
648934604	679	31.21	2	590	1	543	6.0e-100	358	COG0550	DNA topoisomerase IA	570
648934610	305	28.74	3	165	10	156	2.0e-18	86.9	COG2184	Fido, protein-threonine AMPylation domain	201
648934614	277	15.08	42	256	2	250	3.0e-09	56	COG1192	Cellulose biosynthesis protein BcsQ	259
648934617	649	28.69	13	581	10	590	5.0e-90	325	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
648934619	98	54.08	1	97	2	98	6.0e-23	99.2	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
648934621	248	35.32	34	238	2	216	2.0e-27	116	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
648934622	1009	26.52	649	974	1	317	1.0e-35	145	COG4644	Transposase and inactivated derivatives, TnpA family	323
648934625	90	26.51	6	88	3	82	5.0e-06	42.8	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
648934628	188	39.11	1	185	2	203	9.0e-29	119	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
648934630	906	34.92	325	895	237	862	1.0e-88	321	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
648934631	645	44.51	288	614	1	323	8.0e-96	345	COG4644	Transposase and inactivated derivatives, TnpA family	323
648934639	127	28.45	12	127	30	145	9.0e-06	42.7	COG5490	Uncharacterized protein	158
648934640	1749	35.34	1502	1749	97	335	3.0e-40	162	COG0642	Signal transduction histidine kinase	336
648934641	347	27.97	44	342	1	299	8.0e-48	184	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
648934642	569	32.18	14	553	12	540	3.0e-83	302	COG1178	ABC-type Fe3+ transport system, permease component	540
648934643	208	64.08	3	207	6	211	8.0e-81	293	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
648934644	231	58.9	1	219	1	218	2.0e-84	305	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
648934646	273	48.48	1	263	5	267	1.0e-64	240	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
648934647	309	49.83	15	309	8	286	6.0e-73	267	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
648934648	382	51.8	23	382	4	352	1.0e-120	426	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
648934649	363	44.88	4	363	12	363	5.0e-95	341	COG0687	Spermidine/putrescine-binding periplasmic protein	363
648934650	462	34.8	24	462	8	441	5.0e-97	348	COG0174	Glutamine synthetase	443
648934651	227	30.84	3	227	1	226	8.0e-33	133	COG1802	DNA-binding transcriptional regulator, GntR family	230
648934652	467	36.9	23	466	4	443	9.0e-114	404	COG0174	Glutamine synthetase	443
648934653	492	45.66	10	453	2	444	0.0e+00	521	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
648934654	253	39.36	10	249	4	250	1.0e-58	219	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
648934655	552	37.84	1	547	1	509	0.0e+00	493	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
648934657	481	54.43	224	460	1	235	7.0e-72	265	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
648934658	361	25.14	25	356	113	450	1.0e-22	100	COG1231	Monoamine oxidase	450
648934659	225	22.92	5	225	7	246	7.0e-16	77.6	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
648934661	169	33.33	21	169	51	184	1.0e-17	82.5	COG0693	Putative intracellular protease/amidase	188
648934663	307	46.52	1	306	1	315	3.0e-93	335	COG0435	Glutathionyl-hydroquinone reductase	324
648934666	388	33.16	1	378	2	384	1.0e-62	234	COG0183	Acetyl-CoA acetyltransferase	392
648934668	555	39.22	27	520	1	492	3.0e-95	342	COG0366	Glycosidase	505
648934669	264	18	7	247	5	245	1.0e-09	57.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
648934670	397	19.88	1	307	10	341	5.0e-09	56.1	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
648934671	410	32.85	4	403	2	408	2.0e-97	349	COG2081	Predicted flavoprotein YhiN	408
648934672	152	45.64	1	149	1	149	1.0e-45	175	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
648934673	70	52.17	2	70	1	67	9.0e-17	78.3	COG1278	Cold shock protein, CspA family	67
648934674	289	30	1	275	1	278	9.0e-46	177	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
648934675	261	49.41	9	261	8	259	4.0e-72	264	COG3931	Predicted N-formylglutamate amidohydrolase	263
648934676	195	24.73	9	192	11	166	3.0e-14	71.8	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
648934677	440	35.12	1	439	2	447	2.0e-69	256	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
648934678	349	23.01	4	339	3	346	3.0e-26	113	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
648934679	455	35.65	6	454	2	443	8.0e-110	391	COG0174	Glutamine synthetase	443
648934680	462	34.85	2	459	13	468	2.0e-104	372	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648934681	383	42.52	7	383	2	377	3.0e-110	391	COG1454	Alcohol dehydrogenase, class IV	377
648934682	282	50	5	282	7	283	3.0e-89	321	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
648934683	314	47.12	7	301	8	302	1.0e-88	320	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
648934684	208	22.34	1	193	4	200	1.0e-12	66.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648934685	552	53.49	1	535	4	540	0.0e+00	512	COG2303	Choline dehydrogenase or related flavoprotein	542
648934686	487	45.21	7	482	1	471	0.0e+00	501	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648934688	392	48.51	1	392	1	403	0.0e+00	476	COG2081	Predicted flavoprotein YhiN	408
648934689	153	43.28	1	133	1	133	4.0e-31	127	COG1959	DNA-binding transcriptional regulator, IscR family	150
648934690	158	36	3	152	2	148	3.0e-28	117	COG2994	ACP:hemolysin acyltransferase (hemolysin-activating protein)	148
648934694	433	31.51	207	425	19	211	8.0e-27	115	COG2114	Adenylate cyclase, class 3	227
648934697	400	34.9	17	392	1	356	1.0e-39	157	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648934698	324	35.67	9	308	27	310	6.0e-45	174	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
648934699	290	36.14	11	289	10	294	7.0e-41	161	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
648934700	235	49.37	2	235	1	237	4.0e-81	294	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
648934701	256	45.6	1	250	4	250	5.0e-77	281	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
648934702	447	40.44	252	433	4	181	5.0e-35	142	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
648934704	464	45.74	179	460	1	262	3.0e-80	292	COG1760	L-serine deaminase	262
648934705	134	38.1	5	130	6	127	1.0e-19	89.2	COG3788	Uncharacterized membrane protein YecN, MAPEG domain	131
648934706	205	37.75	4	205	19	222	3.0e-32	132	COG1802	DNA-binding transcriptional regulator, GntR family	230
648934708	450	41.28	4	450	1	448	0.0e+00	501	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
648934711	621	52.37	4	621	1	622	0.0e+00	714	COG0326	Molecular chaperone, HSP90 family	623
648934714	236	40.38	9	215	2	209	4.0e-42	165	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
648934721	700	39.33	1	685	1	686	0.0e+00	603	COG4789	Type III secretory pathway, component EscV	689
648934724	250	36.89	15	232	6	230	1.0e-44	173	COG4669	Type III secretory pathway, lipoprotein EscJ	246
648934728	444	49.2	1	437	1	435	0.0e+00	502	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
648934730	377	19.53	255	375	9	136	3.0e-07	49.6	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
648934731	217	46.19	7	216	3	212	7.0e-59	220	COG4790	Type III secretory pathway, component EscR	214
648934732	89	33.77	11	87	11	87	6.0e-09	52.5	COG4794	Type III secretory pathway, component EscS	89
648934733	267	29.96	22	266	15	257	2.0e-16	79.5	COG4791	Type III secretory pathway, component EscT	259
648934734	350	30.32	5	344	4	344	2.0e-56	213	COG1377	Flagellar biosynthesis protein FlhB	363
648934749	169	42.45	10	148	4	135	2.0e-21	95.8	COG3600	Uncharacterized phage-associated protein	154
