gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
2918591126	384	97.19	49	364	3	313	2.0e-85	280.8	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918591127	350	16.35	258	348	245	296	4.2e-14	20.9	COG0657	Acetyl esterase/lipase	312
2918591127	350	36.48	110	274	74	189	4.2e-14	26.1	COG0657	Acetyl esterase/lipase	312
2918591128	118	68.15	7	117	38	129	4.3e-09	30.9	COG3976	Uncharacterized protein, contains FMN-binding domain	135
2918591129	300	72.19	17	277	58	301	4.7e-37	121.8	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
2918591130	329	98.12	1	316	1	314	2.8e-100	329.7	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918591131	497	39.43	299	491	44	194	1.1e-31	5.7	COG0477	MFS family permease	338
2918591131	497	83.29	32	334	5	323	1.1e-31	99.4	COG0477	MFS family permease	338
2918591132	297	96.68	4	297	2	292	3.9e-71	234.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918591133	436	74.18	190	436	51	231	3.8e-44	145	COG2114	Adenylate cyclase, class 3	227
2918591134	361	53.22	61	317	6	162	1.5e-10	33.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918591135	358	93.18	45	352	21	307	3.7e-42	138.8	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
2918591136	137	83.06	9	137	18	120	3.2e-29	96.1	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918591137	159	92.37	24	150	10	130	1.2e-32	106.8	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918591143	380	55.64	2	356	37	317	1.1e-24	81.4	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2918591146	160	97.62	34	160	2	124	4.3e-45	147	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
2918591147	188	94.03	21	87	2	64	3.4e-46	64.3	COG1278	Cold shock protein, CspA family	67
2918591147	188	95.52	113	179	3	66	3.4e-46	83.7	COG1278	Cold shock protein, CspA family	67
2918591148	146	99.32	1	126	1	145	2.2e-22	75.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918591149	420	97.84	230	412	5	185	3.3e-53	174.3	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
2918591151	248	95.15	1	226	11	226	3.0e-74	243.8	COG0785	Cytochrome c biogenesis protein CcdA	220
2918591152	312	97.76	1	311	4	309	1.5e-68	225.5	COG0679	Predicted permease	311
2918591153	402	98.22	2	383	2	387	7.8e-98	322.8	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918591154	250	97.47	17	248	4	234	2.1e-60	198.9	COG1183	Phosphatidylserine synthase	234
2918591155	523	99.4	9	510	4	501	0.0e+00	617.9	COG3845	ABC-type uncharacterized transport system, ATPase component	501
2918591156	363	98.04	3	361	3	353	3.0e-118	388.9	COG4603	ABC-type uncharacterized transport system, permease component	356
2918591157	306	98.36	1	306	4	302	2.7e-109	359.2	COG1079	ABC-type uncharacterized transport system, permease component	304
2918591158	357	96.88	1	339	8	349	4.5e-96	316.2	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
2918591159	249	93.36	13	248	11	235	4.2e-63	207.2	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918591160	453	98.47	3	443	3	454	0.0e+00	554.3	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
2918591161	608	100	1	608	1	615	0.0e+00	774.5	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
2918591162	167	97.08	1	165	4	169	9.8e-54	176.3	COG3153	Predicted N-acetyltransferase YhbS	171
2918591163	222	91.89	9	221	3	206	4.2e-84	275.7	COG2928	Uncharacterized membrane protein	222
2918591164	127	96.95	2	127	2	128	9.8e-39	127.2	COG3742	Uncharacterized protein, contains PIN domain	131
2918591165	85	78.57	1	80	2	67	7.6e-15	49.4	COG4118	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor	84
2918591167	701	97.35	1	689	5	664	0.0e+00	856.9	COG1200	RecG-like helicase	677
2918591168	103	96.81	1	95	1	91	8.7e-31	100.2	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
2918591169	1165	99.04	8	1165	10	1138	0.0e+00	1365	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
2918591171	310	97.34	2	287	5	297	2.4e-42	139.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918591172	222	97.78	1	222	4	223	1.8e-86	284.1	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
2918591173	615	98.61	1	615	4	569	0.0e+00	506.1	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2918591174	218	98.34	1	180	2	179	1.8e-57	188.1	COG5342	Invasion protein IalB, involved in pathogenesis	181
2918591175	109	95.69	1	109	6	116	3.5e-54	176.4	COG3785	Heat shock protein HspQ	116
2918591176	310	95.35	11	307	8	294	8.4e-41	134.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918591177	469	99.55	2	469	2	445	0.0e+00	596.3	COG0174	Glutamine synthetase	443
2918591178	112	100	1	112	1	112	2.0e-49	161.2	COG0347	Nitrogen regulatory protein PII	112
2918591180	491	94.79	214	490	10	282	2.6e-78	257.9	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
2918591180	491	95.61	7	201	9	204	8.8e-57	185.9	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
2918591181	345	96.92	1	329	4	318	1.3e-129	426.2	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918591183	298	96.35	12	296	6	295	3.1e-54	179.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918591184	300	85.32	5	285	44	293	8.4e-52	170.5	COG0685	5,10-methylenetetrahydrofolate reductase	291
2918591185	261	46.75	37	242	52	195	2.3e-20	67.5	COG0223	Methionyl-tRNA formyltransferase	307
2918591186	53	79.55	1	52	8	42	2.3e-08	27.2	COG5510	Predicted small secreted protein	44
2918591187	250	97.6	1	248	6	249	1.4e-115	379	COG3698	Uncharacterized protein YigE, DUF2233 family	250
2918591190	467	32	1	101	42	129	3.6e-121	9.1	COG1760	L-serine deaminase	262
2918591190	467	100	181	463	1	275	3.6e-121	389	COG1760	L-serine deaminase	262
2918591191	127	88.19	1	127	18	144	7.7e-69	224.6	COG5458	Uncharacterized protein	144
2918591192	202	100	1	190	1	191	1.5e-79	260.7	COG3672	Predicted transglutaminase-like cysteine proteinase	191
2918591195	230	89	31	230	3	188	1.7e-75	247.3	COG5388	Uncharacterized protein	209
2918591196	245	92.54	15	245	4	214	5.4e-48	158.2	COG0705	Membrane associated serine protease, rhomboid family	228
2918591197	144	94.48	2	124	10	163	1.4e-26	88.1	COG0517	CBS domain	117
2918591199	312	94.04	24	312	5	304	5.5e-85	280	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2918591200	150	93.75	11	124	7	111	5.7e-42	136.4	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
2918591201	208	95.94	11	208	8	196	4.9e-84	274.9	COG0302	GTP cyclohydrolase I	195
2918591202	148	96.03	1	147	3	147	3.8e-41	135	COG0822	NifU homolog involved in Fe-S cluster formation	150
2918591203	119	85.87	25	117	11	89	5.6e-32	103.5	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
2918591204	174	98.88	1	174	1	176	6.7e-65	212.8	COG3797	Uncharacterized conserved protein, DUF1697 family	178
2918591205	667	99.49	37	660	1	591	0.0e+00	875.5	COG0441	Threonyl-tRNA synthetase	589
2918591207	193	94.44	6	191	11	214	2.9e-21	70.5	COG0778	Nitroreductase	207
2918591208	203	95.14	1	195	7	182	2.0e-49	162.2	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918591209	378	98.08	1	363	8	364	3.1e-115	379.8	COG5330	Uncharacterized conserved protein, DUF2336 family	364
2918591211	151	64.55	7	150	52	173	1.8e-14	48.4	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918591212	411	96.11	18	384	7	352	2.4e-71	234.9	COG0628	Predicted PurR-regulated permease PerM	355
2918591213	577	99.32	1	571	4	591	0.0e+00	607.5	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918591215	441	97.86	21	441	6	416	0.0e+00	510.1	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
2918591216	122	84.75	1	103	12	111	2.3e-12	41.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918591217	419	48.3	226	417	11	195	5.6e-11	5.1	COG0477	MFS family permease	338
2918591217	419	52.22	19	228	12	211	5.6e-11	37.2	COG0477	MFS family permease	338
2918591218	1272	99.08	24	1012	2	757	0.0e+00	613.8	COG0209	Ribonucleotide reductase alpha subunit	696
2918591221	165	92.74	1	154	13	178	3.4e-30	98.9	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
2918591222	281	71.07	1	281	44	156	1.1e-19	59.5	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918591223	263	98.83	10	254	2	255	4.0e-71	233.8	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
2918591224	199	98.12	1	199	3	211	1.3e-52	173.2	COG0655	Multimeric flavodoxin WrbA	207
2918591230	50	9.89	1	23	93	110	2.4e-03	2	COG3059	Uncharacterized membrane protein YkgB	182
2918591230	50	15.38	18	50	80	107	2.4e-03	12.1	COG3059	Uncharacterized membrane protein YkgB	182
2918591234	223	96.68	7	223	2	205	6.3e-66	216.3	COG2518	Protein-L-isoaspartate O-methyltransferase	209
2918591235	328	100	12	328	1	234	3.5e-77	254.1	COG3827	Cell pole-organizing protein PopZ	231
2918591236	947	99.66	2	945	2	881	0.0e+00	1214.1	COG0525	Valyl-tRNA synthetase	877
2918591237	427	97.97	1	427	10	444	4.2e-94	310.1	COG2067	Long-chain fatty acid transport protein	440
2918591238	264	67.07	19	263	105	326	1.5e-35	117.5	COG0790	TPR repeat	292
2918591239	265	99.23	1	261	1	257	1.2e-83	274.9	COG0708	Exonuclease III	261
2918591240	110	98.18	2	110	3	110	4.3e-42	137	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2918591241	405	97.86	7	401	9	420	0.0e+00	443.8	COG0232	dGTP triphosphohydrolase	412
2918591242	585	100	1	584	1	581	0.0e+00	581	COG0018	Arginyl-tRNA synthetase	577
2918591244	338	74.58	1	334	3	313	5.2e-89	293.6	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2918591245	282	97.18	27	279	2	242	1.3e-71	235.5	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
2918591246	244	97.28	24	204	3	181	9.6e-63	205.2	COG1386	Chromosome segregation and condensation protein ScpB	184
2918591247	68	67.02	1	68	1	63	1.1e-21	71.7	COG1826	Sec-independent protein translocase protein TatA	94
2918591248	245	98.94	1	102	1	93	4.1e-22	73.1	COG1826	Sec-independent protein translocase protein TatA	94
2918591249	267	97.68	3	266	3	255	2.2e-95	313.3	COG0805	Sec-independent protein secretion pathway component TatC	255
2918591250	427	99.54	1	427	1	429	0.0e+00	604.9	COG0172	Seryl-tRNA synthetase	429
2918591251	256	99.22	1	251	1	254	1.1e-88	291.4	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
2918591252	217	94.79	8	216	4	203	3.2e-62	204.1	COG2518	Protein-L-isoaspartate O-methyltransferase	209
2918591253	489	16.46	139	243	5	56	1.2e-47	3.2	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2918591253	489	94.94	252	489	4	303	1.2e-47	155.1	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2918591254	171	98.77	3	164	2	161	1.2e-53	175.9	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
2918591255	212	96.39	4	207	5	191	2.0e-60	198	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
2918591256	399	96.96	4	399	10	392	8.8e-34	111	COG2814	Predicted arabinose efflux permease, MFS family	394
2918591257	322	97.67	3	293	4	297	3.8e-45	148.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918591258	349	99.69	20	349	2	325	5.8e-124	407.6	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
2918591259	122	97.5	2	121	2	118	2.1e-57	186.8	COG3536	Uncharacterized conserved protein, DUF971 family	120
2918591260	603	74.44	386	584	25	190	1.3e-31	104.7	COG1226	Voltage-gated potassium channel Kch	212
2918591260	603	98.25	3	399	4	396	5.9e-108	355.5	COG0475	Kef-type K+ transport system, membrane component KefB	397
2918591261	202	98.85	1	176	1	172	1.3e-52	172.7	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2918591262	356	96.17	116	338	7	182	8.7e-51	166.5	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918591263	405	98.53	1	405	4	404	0.0e+00	443.2	COG0303	Molybdopterin biosynthesis enzyme	404
2918591264	163	98.72	4	161	3	156	9.1e-68	221.4	COG0315	Molybdenum cofactor biosynthesis enzyme	157
2918591265	271	99.61	5	262	1	253	8.8e-101	330.8	COG0134	Indole-3-glycerol phosphate synthase	254
2918591266	337	99.41	1	336	2	339	0.0e+00	435.6	COG0547	Anthranilate phosphoribosyltransferase	338
2918591267	619	93.85	1	391	6	310	1.3e-23	78.6	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918591270	178	98.74	14	177	2	158	2.7e-60	197.2	COG0669	Phosphopantetheine adenylyltransferase	159
2918591271	189	88.54	28	188	3	141	9.3e-46	150.1	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
2918591272	169	87.26	10	167	1	137	2.2e-48	158.6	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
2918591273	360	99.43	1	360	1	347	0.0e+00	477.5	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
2918591274	376	98.12	7	374	1	365	0.0e+00	541.9	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
2918591275	385	56.75	7	381	191	455	6.8e-111	364.3	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2918591276	581	98.48	18	415	7	395	3.8e-99	326.2	COG0019	Diaminopimelate decarboxylase	394
2918591277	510	96.13	1	510	16	561	1.1e-94	312.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918591278	87	91.36	3	86	5	78	2.0e-12	41.5	COG0236	Acyl carrier protein	80
2918591280	375	100	1	375	1	366	0.0e+00	560.1	COG1062	Zn-dependent alcohol dehydrogenase	366
2918591283	191	55.61	19	190	6	114	2.0e-09	31.5	COG4961	Flp pilus assembly protein TadG	185
2918591285	476	99.09	4	470	2	436	0.0e+00	715.2	COG1206	Folate-dependent tRNA-U54 methylase TrmFO/GidA	439
2918591286	47	74.6	1	47	16	62	4.8e-21	68.9	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918591287	48	69.84	1	46	16	59	1.2e-18	61.2	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918591289	492	99.55	1	448	1	446	0.0e+00	484.7	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
2918591292	467	99.34	1	454	3	454	0.0e+00	442.5	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918591293	177	91.1	8	177	2	175	3.7e-68	223.4	COG4420	Uncharacterized membrane protein	191
2918591294	644	98.78	4	642	5	654	0.0e+00	432.7	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
2918591295	559	94.24	9	280	3	264	1.8e-56	185.3	COG0388	Predicted amidohydrolase	274
2918591295	559	97.08	268	549	4	269	3.5e-83	273.3	COG0171	NH3-dependent NAD+ synthetase	268
2918591296	125	94.52	12	123	7	144	1.5e-12	41.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918591297	275	5.13	3	40	277	298	5.2e-51	6.4	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2918591297	275	10.72	221	272	256	301	5.2e-51	9.2	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2918591297	275	37.3	43	229	192	351	5.2e-51	152	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2918591299	238	89.35	30	235	2	194	1.9e-31	104.1	COG0778	Nitroreductase	207
2918591301	771	99.1	1	445	3	440	0.0e+00	580	COG0281	Malic enzyme	432
2918591301	771	99.39	442	770	1	325	9.9e-119	390.3	COG0280	Phosphotransacetylase	327
2918591302	276	99.59	13	250	1	240	1.9e-78	257.5	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
2918591303	327	94.1	1	327	6	356	7.7e-65	213.5	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918591304	386	65.66	21	102	14	78	2.6e-04	14.8	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
2918591304	386	96.25	118	386	10	266	3.5e-90	296.1	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2918591305	278	95.44	12	275	5	255	6.1e-110	360.8	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
2918591306	456	38.38	280	447	150	291	1.7e-69	29.6	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2918591306	456	99.46	1	372	1	368	1.7e-69	213.7	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2918591307	197	97.07	1	197	6	204	2.5e-81	266.6	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
2918591308	321	89.76	7	321	29	361	6.2e-41	134.8	COG4188	Predicted dienelactone hydrolase	365
2918591309	145	95.3	1	145	6	147	4.7e-65	212.5	COG4125	Uncharacterized membrane protein	149
2918591315	79	13.13	1	77	68	140	5.1e-03	9.9	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
2918591318	84	97.56	6	84	1	80	2.1e-23	76.8	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
2918591319	881	96.24	11	849	27	846	0.0e+00	920.4	COG3264	Small-conductance mechanosensitive channel	835
2918591323	837	99.23	1	392	1	385	4.9e-88	290	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918591323	837	99.48	418	837	2	384	7.0e-120	394.4	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
2918591324	277	54.25	8	274	18	253	1.5e-36	120.3	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918591325	519	95.26	7	516	23	484	1.6e-107	354.5	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918591326	104	84.75	1	99	17	116	1.2e-20	68.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918591327	118	20.38	6	57	8	39	6.2e-11	27.4	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2918591327	118	24.84	46	112	86	124	6.2e-11	8.3	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2918591328	202	98	5	202	2	197	5.7e-86	281.8	COG0740	ATP-dependent protease ClpP, protease subunit	200
2918591329	296	96.88	1	281	2	312	6.8e-45	144.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918591330	707	99.53	65	707	4	641	0.0e+00	788.1	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
2918591331	293	18.64	197	279	223	277	1.6e-07	10.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918591331	293	42.37	69	226	7	131	1.6e-07	15	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918591332	256	98.02	3	255	4	250	1.8e-88	290.5	COG0149	Triosephosphate isomerase	251
2918591333	151	95.7	1	108	1	89	4.4e-31	100.9	COG1314	Preprotein translocase subunit SecG	86
2918591334	542	99.25	2	541	2	532	0.0e+00	810.5	COG0504	CTP synthase (UTP-ammonia lyase)	533
2918591335	310	87.74	5	309	28	306	7.7e-33	108.6	COG0657	Acetyl esterase/lipase	312
2918591336	463	99.57	2	463	2	461	0.0e+00	754.7	COG0114	Fumarate hydratase class II	462
2918591337	634	98.26	15	634	9	573	0.0e+00	713.5	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
2918591338	233	95.95	7	224	7	219	7.9e-66	216.5	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918591339	231	99.12	1	230	1	226	9.5e-82	268	COG0120	Ribose 5-phosphate isomerase	227
2918591340	189	98.37	1	186	3	183	4.7e-70	229.8	COG3184	Uncharacterized protein	183
2918591341	462	99.34	2	450	3	454	0.0e+00	473.8	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918591342	286	98.01	4	279	2	296	8.0e-23	75.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918591344	458	99.78	1	446	1	445	0.0e+00	787.2	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
2918591345	579	99.12	7	579	6	565	0.0e+00	791.7	COG4655	Uncharacterized membrane protein	565
2918591346	140	84.69	1	140	14	179	4.0e-38	125.7	COG4961	Flp pilus assembly protein TadG	185
2918591347	280	97.77	57	280	6	224	3.4e-84	276.1	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
2918591348	280	98.71	17	267	3	308	1.6e-88	291.2	COG0024	Methionine aminopeptidase	255
2918591349	239	98.72	1	238	1	232	3.8e-92	302.5	COG1489	DNA-binding protein, stimulates sugar fermentation	235
2918591350	619	99.78	164	619	1	451	0.0e+00	655.9	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
2918591353	241	91.74	5	231	16	215	5.8e-37	121.8	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918591354	449	99.29	7	441	2	418	0.0e+00	438.9	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
2918591355	92	87.65	1	89	5	75	6.8e-23	75.2	COG0236	Acyl carrier protein	80
2918591356	159	83.78	2	130	18	141	2.1e-32	106.2	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2918591357	398	95.41	3	398	2	396	1.2e-73	242.7	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918591358	427	99.03	10	426	3	412	2.1e-126	416.4	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918591359	342	99.7	1	341	2	331	2.3e-98	324	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918591360	309	96.43	3	309	4	300	3.8e-92	303.1	COG1560	Lauroyl/myristoyl acyltransferase	308
2918591362	267	98.07	3	255	3	256	8.2e-59	193.5	COG0730	Uncharacterized membrane protein YfcA	258
2918591363	319	98.4	1	317	2	309	1.3e-103	341.1	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
2918591364	406	98.48	5	393	5	394	3.3e-121	399.4	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918591365	436	98.5	2	326	3	331	3.4e-118	388.7	COG0460	Homoserine dehydrogenase	333
2918591367	605	97.82	64	581	6	498	0.0e+00	523.2	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
2918591370	257	99.17	16	256	2	241	2.7e-117	384.5	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918591371	385	93.42	148	383	15	227	1.6e-67	222.1	COG0765	ABC-type amino acid transport system, permease component	222
2918591372	398	99.24	1	398	4	397	0.0e+00	676.3	COG4597	ABC-type amino acid transport system, permease component	397
2918591373	340	91.52	1	268	4	262	2.4e-44	146	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918591374	395	98.24	8	393	7	396	1.3e-125	413.5	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2918591375	393	99.24	2	388	3	392	1.0e-72	240.2	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918591376	81	100	1	62	1	62	6.8e-31	100.4	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
2918591377	258	96.95	8	258	6	291	7.4e-42	137.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918591378	274	92.35	78	273	6	186	1.7e-81	263.8	COG1045	Serine acetyltransferase	194
2918591380	463	88.6	8	457	48	420	3.4e-94	310.5	COG2124	Cytochrome P450	411
2918591381	219	66.51	1	215	11	149	1.3e-24	82.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918591382	396	99.15	3	388	4	353	2.7e-89	293.7	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918591383	290	98.62	2	290	3	287	3.0e-125	411.5	COG2607	Predicted ATPase, AAA+ superfamily	287
2918591384	115	92.78	13	111	6	95	1.6e-31	102.7	COG1862	Preprotein translocase subunit YajC	97
2918591385	857	13.58	547	644	34	104	0.0e+00	11.6	COG0342	Preprotein translocase subunit SecD	506
2918591385	857	37.48	623	835	315	510	0.0e+00	59.2	COG0342	Preprotein translocase subunit SecD	506
2918591385	857	99.62	1	535	1	521	0.0e+00	657.7	COG0342	Preprotein translocase subunit SecD	506
2918591386	130	100	1	127	1	127	2.0e-59	193.9	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
2918591387	281	97.58	1	281	7	288	5.8e-68	223.8	COG1562	Phytoene/squalene synthetase	288
2918591389	311	98.01	10	304	3	297	4.0e-40	132.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918591390	355	99.12	1	348	3	340	0.0e+00	439.6	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2918591391	243	91.11	10	241	10	214	7.9e-81	264.9	COG0321	Lipoate-protein ligase B	221
2918591394	128	35.54	10	123	154	239	8.4e-05	17.2	COG2202	PAS domain	232
2918591396	141	78.83	5	141	26	133	4.3e-28	92.4	COG1765	Uncharacterized OsmC-related protein	137
2918591397	164	98.82	1	163	2	168	2.3e-49	161.6	COG0242	Peptide deformylase	168
2918591398	101	19.16	2	95	12	43	3.6e-03	11.6	COG3646	Phage regulatory protein Rha	167
2918591399	766	98.02	1	761	14	807	0.0e+00	454	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918591400	475	96.92	30	474	12	451	0.0e+00	538.2	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
2918591401	128	96.21	5	124	1	127	4.6e-28	92.5	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918591402	321	98.77	1	321	5	326	1.8e-127	419.3	COG3503	Uncharacterized membrane protein	323
2918591403	231	97.44	1	231	2	229	1.8e-115	378.7	COG3821	Uncharacterized membrane protein	234
2918591404	173	98.86	6	173	2	174	1.8e-69	227.4	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
2918591405	540	97.73	56	537	8	480	0.0e+00	845.1	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
2918591406	243	98.68	2	239	3	227	4.7e-118	386.9	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
2918591407	50	85	2	50	1	51	5.1e-20	66	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
2918591408	287	50	200	287	62	143	1.3e-49	48.1	COG2010	Cytochrome c, mono- and diheme variants	150
2918591408	287	96.95	51	211	1	159	1.3e-49	122.3	COG2010	Cytochrome c, mono- and diheme variants	150
2918591409	148	97.95	11	136	2	144	6.8e-14	46.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918591410	118	96.85	3	118	3	125	3.0e-35	115.8	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2918591412	527	99.75	41	504	1	396	0.0e+00	475.5	COG0348	Polyferredoxin	386
2918591413	166	99.4	1	166	1	165	1.1e-75	247.4	COG5456	Nitrogen fixation protein FixH	166
2918591414	763	99.32	37	744	2	727	0.0e+00	706.9	COG2217	Cation transport ATPase	713
2918591415	52	82.76	1	52	1	48	9.3e-23	74.5	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
2918591416	476	98.95	1	474	2	470	0.0e+00	712.1	COG0362	6-phosphogluconate dehydrogenase	473
2918591417	108	99.24	1	108	2	131	8.5e-34	108.5	COG5455	Periplasmic regulator RcnB of Ni and Co efflux	129
2918591418	343	98.44	13	335	1	315	2.5e-104	343	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918591419	816	98.93	1	815	9	838	0.0e+00	759.5	COG3250	Beta-galactosidase/beta-glucuronidase	808
2918591420	350	94.61	20	343	1	316	1.2e-71	236	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918591421	330	98.78	1	330	4	326	0.0e+00	446.2	COG4531	ABC-type Zn2+ transport system, periplasmic component/surface adhesin	318
2918591422	310	99.21	9	244	3	254	5.8e-78	255.9	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
2918591423	272	94.2	1	265	11	270	3.6e-83	273.4	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2918591424	137	87.59	1	137	14	140	1.0e-38	126.9	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2918591425	177	93.22	1	176	8	172	6.7e-68	222	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2918591426	229	77.66	8	229	58	269	4.7e-76	250.3	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918591427	336	96	3	331	8	319	1.1e-100	331.3	COG0042	tRNA-dihydrouridine synthase	323
2918591428	266	92.48	5	266	2	247	7.0e-78	256.3	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
2918591429	973	99.57	2	963	4	940	0.0e+00	1490.9	COG0178	Excinuclease UvrABC ATPase subunit	935
2918591430	180	99.42	2	180	2	171	1.7e-51	169.4	COG0629	Single-stranded DNA-binding protein	167
2918591432	382	96.6	1	382	9	377	0.0e+00	581.2	COG3448	CBS-domain-containing membrane protein	382
2918591433	209	98.54	1	209	2	203	6.5e-69	225.8	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
2918591434	927	99.02	3	901	8	812	0.0e+00	1145.8	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
2918591436	468	95.93	1	432	16	392	0.0e+00	444.3	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2918591438	87	22.45	4	34	23	33	1.5e-04	5.9	COG1996	DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger	49
2918591438	87	34.69	58	79	8	24	1.5e-04	8.4	COG1996	DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger	49
2918591444	362	95.97	12	253	3	240	3.0e-71	234.5	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
2918591445	390	95.42	1	390	14	388	6.6e-106	349.3	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2918591446	224	98.56	4	215	2	206	6.9e-71	232.7	COG0125	Thymidylate kinase	208
2918591447	341	52.38	18	328	4	179	1.0e-27	91.4	COG0470	DNA polymerase III, delta prime subunit	324
2918591448	516	97.32	1	516	3	546	0.0e+00	648.1	COG0143	Methionyl-tRNA synthetase	558
2918591449	260	99.22	1	256	2	256	9.3e-86	281.7	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
2918591450	274	97.44	4	274	4	269	2.3e-75	247.7	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2918591451	593	95.96	16	452	16	442	1.0e-98	325.3	COG0038	H+/Cl- antiporter ClcA	443
2918591452	120	74.58	2	103	20	107	7.7e-15	49.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918591453	175	96.62	4	142	3	145	1.8e-24	80.9	COG0394	Protein-tyrosine-phosphatase	139
2918591454	352	96.79	1	343	9	340	2.0e-114	376.5	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
2918591455	140	98.29	1	117	2	116	3.3e-37	121.6	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2918591456	236	99.46	30	222	1	183	1.4e-47	156.2	COG0431	NAD(P)H-dependent FMN reductase	184
2918591457	177	62.43	40	164	67	179	3.9e-32	105.4	COG3038	Cytochrome b561	181
2918591458	206	98.52	4	203	2	201	2.8e-86	282.7	COG4332	Uncharacterized protein	203
2918591459	216	90.7	22	213	14	208	1.2e-38	127.4	COG0625	Glutathione S-transferase	211
2918591460	218	98.44	1	200	1	189	2.6e-74	243.2	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
2918591463	151	98	4	151	2	148	5.1e-60	196.2	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
2918591464	219	96.05	1	219	10	228	2.6e-95	313.1	COG4291	Uncharacterized membrane protein	228
2918591465	277	97.22	1	277	7	321	2.2e-92	304.2	COG0627	S-formylglutathione hydrolase FrmB	316
2918591466	129	93.38	2	129	8	134	9.7e-30	97.7	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918591468	264	99.62	1	262	1	263	2.2e-118	388.7	COG5387	Chaperone required for the assembly of the mitochondrial F1-ATPase	264
2918591469	221	97.3	1	219	4	219	3.4e-55	181.9	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918591470	329	98.63	4	309	4	291	9.9e-76	249.3	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2918591471	125	97.62	1	125	3	125	2.1e-39	128.9	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
2918591473	324	97.4	169	324	5	154	7.3e-51	165.8	COG2847	Copper(I)-binding protein	151
2918591473	324	98.88	1	178	1	176	5.2e-76	248.6	COG4549	Uncharacterized protein YcnI	178
2918591477	379	98.44	3	379	4	382	6.4e-117	385	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
2918591478	120	91.6	1	120	9	128	7.2e-49	159.3	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
2918591479	954	9.46	46	173	93	139	0.0e+00	1	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2918591479	954	31.19	213	395	210	364	0.0e+00	33	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2918591479	954	94.57	450	922	26	495	0.0e+00	714.6	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2918591480	267	12.06	12	89	31	61	1.6e-15	7	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918591480	267	43.19	126	267	142	252	1.6e-15	43.2	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918591482	424	45.17	225	418	22	194	6.8e-09	20.1	COG0477	MFS family permease	338
2918591482	424	53.26	26	258	2	205	6.8e-09	11.5	COG0477	MFS family permease	338
2918591483	270	99.25	14	268	3	268	1.3e-60	199.5	COG1018	Ferredoxin-NADP reductase	266
2918591484	168	98.8	1	167	3	167	1.9e-65	214	COG3749	Uncharacterized conserved protein, DUF934 family	167
2918591485	556	99.81	1	548	1	513	0.0e+00	623.4	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2918591487	487	95.49	225	478	3	235	1.2e-90	297.3	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2918591487	487	97.16	14	222	2	206	1.9e-56	184.8	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
2918591488	195	79.74	3	164	5	126	4.6e-35	115.3	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2918591489	293	52.66	10	286	231	487	4.4e-79	260.9	COG3956	Uncharacterized conserved protein YabN, contains tetrapyrrole methylase and MazG-like pyrophosphatase domain	488
2918591490	479	97.57	34	467	9	410	0.0e+00	492.2	COG2262	50S ribosomal subunit-associated GTPase HflX	411
2918591491	80	97.4	2	78	2	76	3.4e-37	120.4	COG1923	sRNA-binding regulator protein Hfq	77
2918591492	458	97.77	234	454	2	220	4.3e-108	144.2	COG0569	Trk K+ transport system, NAD-binding component	225
2918591492	458	99.55	1	231	1	223	4.3e-108	215	COG0569	Trk K+ transport system, NAD-binding component	225
2918591493	454	97.64	1	454	4	459	0.0e+00	543.5	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918591494	753	99.3	23	742	2	708	0.0e+00	1031.2	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
2918591495	483	98.5	1	482	4	463	0.0e+00	604	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918591496	382	97.8	6	372	5	359	0.0e+00	527.8	COG3852	Signal transduction histidine kinase, nitrogen specific	363
2918591497	308	92.62	1	300	17	317	3.4e-97	319.9	COG0042	tRNA-dihydrouridine synthase	323
2918591498	395	96.98	1	233	4	228	1.6e-75	247.4	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
2918591498	395	98.74	235	393	1	157	2.6e-63	206.9	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
2918591499	169	95.71	4	166	5	160	6.0e-60	195.7	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
2918591500	151	98.63	1	150	1	144	4.1e-59	192.8	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
2918591501	189	87.57	19	187	1	162	1.3e-24	81.7	COG0563	Adenylate kinase or related kinase	178
2918591503	244	79.55	113	243	21	125	1.4e-22	74	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918591504	309	99	1	305	2	299	1.3e-34	114.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918591505	323	98.37	8	313	3	303	0.0e+00	472.3	COG0320	Lipoate synthase	306
2918591506	82	97.56	4	82	1	80	9.8e-24	77.8	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
2918591507	481	99.78	1	471	1	454	0.0e+00	575.9	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918591508	214	93.21	1	214	12	217	1.6e-34	114.3	COG2755	Lysophospholipase L1 or related esterase	216
2918591509	449	99.77	1	449	1	433	0.0e+00	481.6	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2918591510	473	99.38	150	473	2	323	0.0e+00	471.2	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
2918591511	347	91.06	10	347	17	342	0.0e+00	453.2	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
2918591512	92	72.03	1	91	27	111	2.3e-25	83.1	COG2919	Cell division protein FtsB	117
2918591513	424	98.82	1	424	1	420	0.0e+00	678.5	COG0148	Enolase	423
2918591514	281	94.98	6	281	8	272	0.0e+00	451.1	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
2918591516	1446	5.37	296	374	82	127	3.6e-60	4	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918591516	1446	10.75	675	794	37	128	3.6e-60	29	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918591516	1446	30.02	1114	1418	467	723	3.6e-60	74	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918591516	1446	38.32	381	682	285	612	3.6e-60	39.2	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918591516	1446	40.54	798	1163	13	359	3.6e-60	61.2	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918591518	153	14.6	1	140	605	729	9.3e-11	35.5	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918591519	2747	9.46	1919	2097	31	111	1.3e-53	29.8	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918591519	2747	9.7	1816	1943	22	104	1.3e-53	24.8	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918591519	2747	10.86	2150	2257	40	132	1.3e-53	27.6	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918591519	2747	11.33	2081	2212	32	128	1.3e-53	40.8	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918591519	2747	19.63	2544	2730	57	224	1.3e-53	8.5	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918591519	2747	30.26	2230	2549	27	285	1.3e-53	86.4	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918591520	624	93.51	1	621	30	605	0.0e+00	466.1	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
2918591521	150	53.12	1	148	110	245	1.8e-17	58.4	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
2918591522	149	92.95	5	148	8	152	3.5e-25	83.6	COG2165	Type II secretory pathway, pseudopilin PulG	149
2918591523	214	42.79	12	209	7	92	1.2e-10	34	COG4795	Type II secretory pathway, component PulJ	194
2918591524	122	27.56	1	91	9	51	1.8e-07	26.3	COG2165	Type II secretory pathway, pseudopilin PulG	149
2918591525	153	77.17	1	145	8	149	1.9e-14	47.5	COG4970	Tfp pilus assembly protein FimT	181
2918591526	403	99.5	1	402	1	396	1.6e-82	271.7	COG1459	Type II secretory pathway, component PulF	397
2918591527	538	97.64	66	535	11	506	0.0e+00	530.7	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2918591531	338	63.94	180	336	29	161	1.4e-08	28.4	COG3166	Tfp pilus assembly protein PilN	206
2918591532	240	99.01	1	240	3	203	5.8e-85	278.3	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2918591533	225	92.56	4	206	6	204	4.0e-36	119.2	COG0625	Glutathione S-transferase	211
2918591534	845	97.89	49	667	11	475	5.5e-93	306.9	COG0658	Predicted membrane metal-binding protein	453
2918591535	429	99.49	26	429	3	396	0.0e+00	552.1	COG0372	Citrate synthase	390
2918591536	244	98.35	2	242	2	239	2.7e-106	348.5	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918591537	219	94.3	1	216	14	228	2.8e-69	227.7	COG0765	ABC-type amino acid transport system, permease component	222
2918591538	223	88.6	3	214	16	217	1.1e-63	209.1	COG0765	ABC-type amino acid transport system, permease component	222
2918591539	261	97.17	1	261	1	275	6.9e-56	184.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918591540	236	93.97	1	220	10	227	1.3e-55	182.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918591541	394	99.47	4	388	2	379	3.1e-129	425.4	COG0763	Lipid A disaccharide synthetase	381
2918591542	290	98.21	1	281	5	278	2.6e-113	372.3	COG3494	Uncharacterized conserved protein, DUF1009 family	279
2918591543	271	98.85	5	265	3	259	4.6e-103	338.3	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
2918591544	155	95.27	9	153	4	144	5.0e-54	176.5	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2918591545	341	98.22	1	340	6	337	1.1e-124	410.2	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
2918591546	774	99.22	1	774	7	774	0.0e+00	824.9	COG4775	Outer membrane protein assembly factor BamA	766
2918591547	377	98.76	11	377	4	400	8.2e-104	342.5	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
2918591548	277	97.82	4	262	3	271	2.0e-64	212.4	COG0575	CDP-diglyceride synthetase	265
2918591549	247	92.06	1	237	20	251	1.4e-102	336.9	COG0020	Undecaprenyl pyrophosphate synthase	245
2918591550	185	96.26	1	185	8	187	4.0e-77	252.4	COG0233	Ribosome recycling factor	187
2918591551	240	99.16	4	239	2	237	3.2e-92	302.8	COG0528	Uridylate kinase	238
2918591552	308	99.66	1	308	1	296	1.8e-113	373	COG0264	Translation elongation factor EF-Ts	296
2918591553	255	92.97	1	254	6	243	3.1e-107	351.8	COG0052	Ribosomal protein S2	252
2918591556	156	92.65	8	155	9	134	4.8e-24	79	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918591557	246	91.88	2	240	9	257	2.9e-42	139.5	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2918591558	397	98.97	1	391	4	386	0.0e+00	620.2	COG3146	Predicted N-acyltransferase	387
2918591559	143	98.58	8	142	2	140	1.4e-42	139.3	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2918591560	283	96.97	1	278	9	264	1.4e-102	336.9	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
2918591561	267	90.03	1	258	27	297	1.4e-42	140.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918591562	316	85.34	85	309	18	215	1.7e-01	11.2	COG0671	Membrane-associated phospholipid phosphatase	232
2918591564	252	82.85	5	242	30	227	3.1e-07	24.4	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
2918591565	835	40.75	428	766	470	797	0.0e+00	453.2	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918591565	835	49.81	3	437	2	402	0.0e+00	523.8	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918591566	118	92.52	14	118	9	107	5.5e-45	146.1	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
2918591567	860	64.84	731	860	7	124	1.1e-11	38.5	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918591567	860	80.2	315	709	77	392	5.1e-65	215	COG0642	Signal transduction histidine kinase	336
2918591569	410	39.29	5	136	28	82	8.7e-04	12.4	COG3190	Flagellar biogenesis protein FliO	137
2918591570	139	99.17	19	138	1	119	3.2e-45	148	COG1734	RNA polymerase-binding transcription factor DksA	120
2918591571	169	95.71	6	169	3	158	1.3e-45	149.5	COG2062	Phosphohistidine phosphatase SixA	163
2918591572	492	99.57	8	492	3	460	0.0e+00	693.8	COG3106	Predicted ATPase, YcjX-like family	467
2918591573	359	98.57	8	359	2	346	0.0e+00	464.9	COG3768	Uncharacterized membrane protein YcjF, UPF0283 family	350
2918591575	175	97.52	5	163	2	158	3.0e-59	193.6	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
2918591576	121	97.52	2	121	2	119	2.1e-39	129	COG1539	Dihydroneopterin aldolase	121
2918591577	261	93.88	1	261	12	272	2.4e-94	310.2	COG0294	Dihydropteroate synthase	274
2918591578	193	89.52	1	193	18	205	4.9e-95	311.3	COG5661	Predicted secreted Zn-dependent protease	210
2918591580	106	99.03	1	105	1	102	4.0e-27	88.5	COG0633	Ferredoxin	102
2918591581	122	71.2	20	116	11	99	5.5e-10	33.8	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918591582	2115	32.61	515	612	62	106	1.9e-02	6.4	COG3105	Uncharacterized membrane-anchored protein YhcB, DUF1043 family	138
2918591582	2115	56.52	1036	1138	37	114	1.9e-02	4.4	COG3105	Uncharacterized membrane-anchored protein YhcB, DUF1043 family	138
2918591584	649	22.22	1	178	10	171	3.0e-121	207.1	COG0480	Translation elongation factor EF-G, a GTPase	697
2918591584	649	67.76	172	644	218	711	3.0e-121	190.6	COG0480	Translation elongation factor EF-G, a GTPase	697
2918591585	305	98.97	1	305	4	292	6.6e-96	315.8	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
2918591586	257	86.32	2	257	33	278	6.9e-58	190.3	COG0061	NAD kinase	281
2918591588	156	95.15	1	156	4	199	5.8e-14	46.2	COG1335	Nicotinamidase-related amidase	205
2918591589	342	99.16	92	330	2	238	2.5e-115	378.6	COG1186	Protein chain release factor B	239
2918591590	805	97.36	1	805	13	786	0.0e+00	1032.5	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
2918591591	419	92.48	92	414	19	264	7.9e-70	229.6	COG0860	N-acetylmuramoyl-L-alanine amidase	231
2918591592	965	99.8	2	672	2	489	0.0e+00	854.7	COG1530	Ribonuclease G or E	487
2918591593	234	98.51	1	232	4	267	1.5e-51	169.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918591594	121	97.17	1	102	1	103	1.3e-23	77.4	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
2918591596	227	76.27	1	100	16	105	1.5e-16	54.6	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918591597	387	98.23	7	387	4	392	8.2e-105	345.4	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918591598	255	97.19	1	248	7	248	4.2e-54	178.2	COG1651	Protein-disulfide isomerase	244
2918591599	145	96.58	3	145	2	142	6.3e-68	221.4	COG0757	3-dehydroquinate dehydratase	146
2918591600	162	99.32	13	162	1	146	3.1e-42	139.3	COG0511	Biotin carboxyl carrier protein	140
2918591601	448	99.33	1	446	1	447	0.0e+00	682.6	COG0439	Biotin carboxylase	449
2918591602	214	85.52	2	207	20	208	6.4e-86	281	COG2360	Leu/Phe-tRNA-protein transferase	221
2918591604	145	82.93	2	144	28	163	1.6e-65	214.5	COG4765	Uncharacterized protein	164
2918591605	132	100	9	131	1	118	1.3e-61	200.8	COG3761	NADH:ubiquinone oxidoreductase 17.2 kD subunit	118
2918591606	157	84.57	9	154	18	154	6.0e-14	46.9	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918591607	165	35.45	5	154	103	169	1.7e-14	48.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918591608	501	98.96	17	499	4	481	0.0e+00	685.9	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
2918591609	110	93.62	1	94	4	91	1.6e-33	109.2	COG3326	Uncharacterized membrane protein YsdA, DUF1294 family	94
2918591610	188	57.14	5	179	69	176	6.8e-20	66.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918591611	85	100	1	85	1	85	1.5e-39	128.5	COG3811	Uncharacterized protein YjhX, UPF0386 family	85
2918591612	155	67.72	1	138	40	167	7.9e-20	66	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918591613	493	99.79	1	492	1	480	0.0e+00	644.6	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918591614	95	98.96	1	95	1	95	2.6e-32	105.6	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
2918591615	234	93.58	1	234	8	255	7.0e-62	203.5	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
2918591616	100	91.96	1	100	9	111	2.0e-37	122.2	COG2824	Uncharacterized Zn-ribbon-containing protein	112
2918591617	159	97.16	16	155	2	138	3.9e-44	144.5	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
2918591620	214	78.95	8	212	5	169	8.4e-18	60.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918591621	203	77.16	7	193	31	155	5.5e-09	30.5	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918591622	550	18.05	457	532	61	132	5.8e-79	3.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918591622	550	92.73	36	450	25	394	5.8e-79	260.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918591623	192	88.94	1	191	3	187	6.4e-18	58.9	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918591625	313	98.41	2	309	5	314	3.8e-122	401.4	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
2918591626	430	97.22	3	430	3	421	0.0e+00	471.7	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2918591627	205	98.05	10	202	4	204	4.2e-69	226.9	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
2918591628	380	99.16	13	377	2	357	2.3e-116	383.2	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
2918591630	894	98.26	1	590	1	565	0.0e+00	678.9	COG0550	DNA topoisomerase IA	570
2918591630	894	99.06	583	889	3	319	2.2e-113	372.6	COG1754	Uncharacterized C-terminal domain of topoisomerase IA	298
2918591631	784	99.16	34	750	5	709	0.0e+00	702	COG0557	Exoribonuclease R	706
2918591632	147	96.03	9	135	5	125	1.4e-55	180.8	COG5349	Uncharacterized conserved protein, DUF983 family	126
2918591633	208	81.98	1	180	14	154	8.6e-23	75.4	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918591634	391	47.26	201	390	8	188	1.1e-16	28.6	COG0477	MFS family permease	338
2918591634	391	72.58	12	236	3	280	1.1e-16	30.1	COG0477	MFS family permease	338
2918591635	55	94.12	3	53	4	51	1.1e-20	68.2	COG0267	Ribosomal protein L33	50
2918591637	456	99.54	15	456	1	433	0.0e+00	546.7	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918591638	123	92.48	1	123	6	128	5.2e-35	114.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918591640	86	74.74	2	83	22	92	9.0e-17	56.1	COG3514	Uncharacterized conserved protein, DUF4415 family	93
2918591641	95	95.7	1	89	4	92	6.5e-28	91.2	COG2929	Uncharacterized conserved protein, DUF497 family	93
2918591642	427	46	5	40	17	39	1.7e-03	11.7	COG1552	Ribosomal protein L40E	50
2918591642	427	98.4	43	390	2	369	1.7e-104	344.2	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918591643	412	78.15	174	391	13	198	9.1e-19	62.3	COG3409	Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases	185
2918591644	1167	99.39	17	1167	2	1151	0.0e+00	1403	COG0587	DNA polymerase III, alpha subunit	1139
2918591645	227	96.9	6	226	2	220	4.7e-77	252.5	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918591646	435	99.76	21	435	2	410	0.0e+00	496.7	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2918591647	440	31.12	251	440	362	525	0.0e+00	186.2	COG0442	Prolyl-tRNA synthetase	500
2918591647	440	42.88	1	255	1	226	0.0e+00	354.8	COG0442	Prolyl-tRNA synthetase	500
2918591649	89	100	1	89	1	89	8.7e-44	142.4	COG5454	Predicted secreted protein	89
2918591650	555	99.09	1	553	5	546	0.0e+00	606.1	COG0595	mRNA degradation ribonuclease J1/J2	555
2918591651	246	98.33	11	246	2	236	3.5e-65	214.5	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
2918591652	480	98.32	7	480	4	471	0.0e+00	561.8	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
2918591653	503	98.59	2	499	2	492	0.0e+00	673.7	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
2918591654	665	99.51	3	658	3	616	0.0e+00	783.3	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2918591655	102	99	2	102	2	100	7.6e-41	132.6	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
2918591656	204	100	1	173	1	168	1.1e-58	192	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
2918591657	163	88.57	2	163	6	160	5.5e-59	193.1	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
2918591658	348	99.1	2	346	2	331	0.0e+00	445.8	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
2918591659	693	99.59	1	693	1	728	0.0e+00	839.8	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
2918591660	434	98.35	1	420	6	422	0.0e+00	647.3	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2918591661	369	95.78	7	175	6	164	2.3e-64	209.9	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2918591661	369	98.5	231	358	2	132	1.3e-42	140.3	COG3743	 Predicted 5' DNA nuclease, flap endonuclease-1-like, helix-3-turn-helix (H3TH) domain	133
2918591663	396	98.24	1	396	8	398	0.0e+00	604.2	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
2918591664	142	95.56	4	133	3	131	1.5e-30	100.2	COG3791	Uncharacterized conserved protein	133
2918591665	200	96.67	1	177	6	179	2.2e-61	201.4	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
2918591666	192	81.96	24	192	8	166	5.1e-82	268	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
2918591667	121	98.36	1	121	2	121	1.1e-47	155.5	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
2918591673	91	95.74	1	91	2	91	1.9e-36	118.7	COG0776	Bacterial nucleoid DNA-binding protein	94
2918591674	805	98.72	3	781	9	782	0.0e+00	1161.6	COG0466	ATP-dependent Lon protease, bacterial type	782
2918591676	425	99.27	19	424	1	406	0.0e+00	688.3	COG1219	ATP-dependent protease Clp, ATPase subunit	408
2918591677	210	98	8	208	2	197	2.8e-90	295.9	COG0740	ATP-dependent protease ClpP, protease subunit	200
2918591678	415	93.44	197	377	12	182	6.6e-48	157.1	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918591679	415	97.62	1	415	9	419	2.4e-107	353.9	COG2124	Cytochrome P450	411
2918591680	252	98.88	3	250	3	267	5.7e-64	210.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918591681	78	20.13	1	73	33	94	2.6e-05	18.1	COG4189	Predicted transcriptional regulator	308
2918591682	113	99.14	1	113	1	115	9.3e-42	136.1	COG3450	Predicted enzyme of the cupin superfamily	116
2918591684	427	99.3	1	427	3	426	0.0e+00	683	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
2918591685	144	96.43	3	144	3	137	6.6e-53	172.3	COG1832	Predicted CoA-binding protein	140
2918591686	278	96.01	1	278	6	294	1.6e-22	74.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918591687	154	98.65	1	149	1	146	1.4e-66	217.4	COG0102	Ribosomal protein L13	148
2918591688	155	95.49	23	155	7	133	5.7e-53	173.2	COG0103	Ribosomal protein S9	130
2918591689	317	98.71	22	313	3	307	1.3e-86	285	COG0010	Arginase family enzyme	305
2918591690	310	95.7	1	310	2	335	9.1e-88	287.4	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
2918591691	281	99.27	1	281	3	274	4.9e-118	387.6	COG3570	Streptomycin 6-kinase	274
2918591692	372	97.65	26	369	3	335	3.6e-119	391.6	COG1612	Heme A synthase	323
2918591693	70	18.15	2	65	42	92	7.0e-04	13.2	COG2339	Membrane proteinase PrsW, cleaves anti-sigma factor RsiW, M82 family	274
2918591694	408	99.51	1	408	1	404	0.0e+00	482.8	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
2918591695	755	76.92	498	744	12	231	6.2e-28	91.4	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918591695	755	96.77	4	467	11	460	1.1e-122	404.1	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918591696	190	75.5	4	190	21	208	3.8e-56	184.6	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918591697	380	96.82	7	380	11	406	1.1e-40	134.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918591698	517	98.67	283	517	4	225	1.8e-84	276.7	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2918591699	413	91.61	8	411	20	412	1.7e-01	1.3	COG3307	O-antigen ligase	424
2918591702	178	97.65	1	176	3	168	7.8e-75	244.9	COG4803	Uncharacterized membrane protein	170
2918591706	184	75.2	2	184	27	214	5.4e-39	128.6	COG2365	Protein tyrosine/serine phosphatase	249
2918591707	195	98.14	1	166	1	158	2.2e-45	148.6	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
2918591709	214	98.56	4	214	2	207	6.2e-82	268.4	COG3932	Uncharacterized conserved protein	209
2918591710	72	10.04	4	68	334	378	1.5e-03	11.6	COG1457	Purine-cytosine permease or related protein	442
2918591715	185	95.83	4	172	7	167	3.5e-36	119.5	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2918591717	479	99.35	4	476	3	462	0.0e+00	565.2	COG0415	Deoxyribodipyrimidine photolyase	461
2918591718	345	99.01	3	314	3	301	1.1e-109	360.4	COG0031	Cysteine synthase	300
2918591719	245	97.94	2	244	3	240	1.4e-86	284.5	COG2872	Ser-tRNA(Ala) deacylase AlaX (editing enzyme)	241
2918591720	473	57.41	314	457	63	155	5.8e-06	19.9	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918591720	473	97.56	2	284	7	286	9.1e-99	324.2	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2918591724	662	98.67	11	590	6	526	0.0e+00	555.3	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
2918591725	322	98.67	5	302	1	297	3.1e-53	175.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918591726	205	100	1	202	1	202	3.9e-76	249.4	COG1182	FMN-dependent NADH-azoreductase	202
2918591727	421	97.27	237	414	4	181	2.5e-41	135.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918591728	103	100	2	101	1	96	5.8e-44	142.8	COG5453	Uncharacterized protein	96
2918591729	416	97.4	1	344	10	346	3.9e-117	385.7	COG1171	Threonine dehydratase	347
2918591730	485	97.47	4	485	3	503	2.1e-120	397.2	COG0168	Trk-type K+ transport system, membrane component	499
2918591731	84	93.15	17	84	4	71	4.0e-14	47.3	COG2608	Copper chaperone CopZ	71
2918591732	497	93.25	2	495	29	567	4.9e-96	317.1	COG0747	ABC-type transport system, periplasmic component	556
2918591733	336	96.56	17	324	3	311	2.6e-107	353.2	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918591734	355	99.08	20	341	1	322	5.3e-112	368.3	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918591735	301	88.93	10	299	24	288	5.0e-86	282.6	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918591736	314	99.06	1	312	1	315	5.2e-98	322.8	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918591737	162	92.42	1	126	1	122	7.1e-33	108.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918591738	336	77.67	5	96	16	95	2.4e-13	43.5	COG0633	Ferredoxin	102
2918591738	336	84.05	96	332	9	224	3.5e-57	187.5	COG0543	NAD(P)H-flavin reductase	252
2918591739	834	9.44	7	78	3	71	0.0e+00	35.1	COG2217	Cation transport ATPase	713
2918591739	834	99.45	74	820	2	728	0.0e+00	897.4	COG2217	Cation transport ATPase	713
2918591741	242	98.97	18	242	2	193	2.6e-23	76.6	COG1525	Endonuclease YncB, thermonuclease family	192
2918591742	177	68.18	9	174	2	91	1.1e-22	75.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918591743	98	87.23	1	84	11	92	3.1e-28	92.2	COG0776	Bacterial nucleoid DNA-binding protein	94
2918591744	323	98.77	1	323	4	325	0.0e+00	445.7	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2918591745	353	98.82	1	340	2	336	9.2e-130	426.9	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
2918591746	187	76.54	28	187	42	178	4.6e-10	31.4	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
2918591747	253	98.33	75	253	1	177	4.2e-87	285.2	COG5452	Uncharacterized protein	180
2918591748	176	95.33	16	160	5	147	7.4e-43	140.5	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
2918591749	712	99.43	1	712	3	701	0.0e+00	1149.4	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
2918591750	407	38.64	269	407	56	203	6.7e-15	22.7	COG0477	MFS family permease	338
2918591750	407	68.41	8	275	13	274	6.7e-15	32.5	COG0477	MFS family permease	338
2918591751	165	94.12	8	163	8	151	1.9e-43	142.4	COG0781	Transcription termination factor NusB	151
2918591752	148	93.42	1	145	11	152	5.0e-52	170.2	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
2918591753	210	99.04	2	210	2	207	1.9e-55	181.7	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918591754	203	94.63	1	203	1	194	6.8e-71	232	COG0307	Riboflavin synthase alpha chain	204
2918591755	414	97.95	2	147	3	145	8.6e-57	184.6	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
2918591755	414	99.55	148	414	1	219	6.6e-76	244.5	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
2918591756	159	98.08	1	156	1	153	4.6e-66	216	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
2918591757	429	98.8	5	427	5	414	0.0e+00	659.9	COG0112	Glycine/serine hydroxymethyltransferase	413
2918591758	443	76.87	1	433	133	574	0.0e+00	551.2	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
2918591759	170	78.95	27	160	7	111	1.7e-18	60.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918591761	337	98.48	8	337	5	329	0.0e+00	467.9	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
2918591762	152	86.36	3	152	4	155	2.5e-28	93.5	COG1714	Uncharacterized membrane protein YckC, RDD family	172
2918591763	252	95.65	1	252	4	245	1.2e-107	353.6	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
2918591764	750	91.51	7	749	7	750	0.0e+00	867.7	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
2918591766	493	94.85	1	490	7	540	0.0e+00	443.7	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2918591767	701	19.29	207	387	78	159	2.0e-98	17	COG0840	Methyl-accepting chemotaxis protein	408
2918591767	701	81.18	349	687	81	425	2.0e-98	311.2	COG0840	Methyl-accepting chemotaxis protein	408
2918591768	158	45.35	4	158	2	152	2.7e-44	146.1	COG4129	Uncharacterized membrane protein YgaE, UPF0421/DUF939 family	332
2918591769	595	99.66	4	592	1	584	0.0e+00	790.4	COG0173	Aspartyl-tRNA synthetase	585
2918591770	423	42.56	3	204	8	170	3.4e-23	29.9	COG0477	MFS family permease	338
2918591770	423	49.61	191	407	3	192	3.4e-23	52.1	COG0477	MFS family permease	338
2918591771	386	99.72	2	365	1	361	0.0e+00	444	COG0349	Ribonuclease D	361
2918591773	342	85.66	118	342	26	234	3.9e-39	128.8	COG2114	Adenylate cyclase, class 3	227
2918591774	452	99.03	10	439	5	412	0.0e+00	488.8	COG4222	Uncharacterized conserved protein	391
2918591777	210	84.74	4	179	23	183	9.7e-40	130.5	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918591778	507	98.79	13	507	4	492	0.0e+00	446.3	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
2918591779	767	98.86	50	748	6	696	0.0e+00	994.9	COG0855	Polyphosphate kinase	696
2918591780	242	59.58	1	242	83	340	4.0e-43	138.1	COG0593	Chromosomal replication initiation ATPase DnaA	408
2918591781	385	94.72	3	361	11	351	3.0e-95	313.6	COG0628	Predicted PurR-regulated permease PerM	355
2918591782	264	64.11	2	203	86	269	1.2e-13	45.2	COG4976	Predicted methyltransferase, contains TPR repeat	287
2918591783	357	98.26	6	352	3	341	0.0e+00	488.4	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
2918591784	224	99	11	210	1	198	3.6e-79	259.4	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
2918591785	311	96.18	1	311	13	314	2.4e-79	260.8	COG4571	Outer membrane protease	314
2918591786	82	80.95	5	82	3	70	1.1e-16	55.2	COG4118	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor	84
2918591787	132	92.54	1	131	4	127	6.3e-22	72.8	COG4113	Predicted nucleic acid-binding protein, contains PIN domain	134
2918591788	205	92.44	43	203	3	161	2.9e-20	67.2	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918591789	740	96.42	7	735	28	808	0.0e+00	473.8	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918591790	287	99.64	1	281	1	278	1.7e-121	398.9	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
2918591791	315	96.91	1	311	10	323	1.5e-71	235.8	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2918591792	252	96	1	252	10	249	3.2e-83	273.3	COG3719	Ribonuclease I	249
2918591793	198	94.88	1	198	1	204	5.7e-35	115.6	COG0625	Glutathione S-transferase	211
2918591794	218	98.73	4	218	4	236	6.7e-46	151.5	COG3637	Opacity protein and related surface antigens	199
2918591795	215	83.21	1	206	45	267	7.5e-28	92.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918591796	681	99.67	54	675	3	598	0.0e+00	787.5	COG0322	Excinuclease UvrABC, nuclease subunit	581
2918591797	195	93.3	1	195	10	190	4.3e-53	174.8	COG0558	Phosphatidylglycerophosphate synthase	192
2918591798	84	100	1	84	1	84	3.2e-24	80	COG1977	Molybdopterin converting factor, small subunit	84
2918591799	151	96.64	1	149	4	147	2.8e-47	154.8	COG0314	Molybdopterin synthase catalytic subunit	149
2918591800	298	96.01	1	297	3	291	5.4e-56	184.7	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918591801	183	34.69	104	183	125	192	2.2e-54	108.7	COG5516	Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding	196
2918591801	183	44.39	1	110	1	87	2.2e-54	73	COG5516	Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding	196
2918591803	140	98.52	2	136	2	134	5.1e-60	195.7	COG0105	Nucleoside diphosphate kinase	135
2918591804	231	92.56	13	231	6	204	2.0e-25	84.2	COG0625	Glutathione S-transferase	211
2918591805	348	95.08	151	330	8	181	7.3e-43	140.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918591806	637	98.88	9	530	2	530	0.0e+00	577.7	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918591807	160	97.87	21	160	2	139	2.8e-41	135.4	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2918591808	202	96.53	1	200	6	200	4.5e-70	229.7	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918591809	568	81.73	226	568	70	391	6.2e-45	149.1	COG0642	Signal transduction histidine kinase	336
2918591810	646	34.43	179	359	16	78	8.1e-08	25.8	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918591810	646	92.61	391	644	10	247	4.5e-61	200	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918591811	395	96.17	189	373	6	181	2.3e-48	158.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918591812	308	94.3	1	303	2	332	2.5e-44	146.1	COG0673	Predicted dehydrogenase	342
2918591813	342	94.54	160	339	8	180	9.7e-51	166.3	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918591814	149	100	1	147	1	144	2.9e-48	158	COG2927	DNA polymerase III, chi subunit	144
2918591815	497	98.97	5	496	5	486	0.0e+00	572.4	COG0260	Leucyl aminopeptidase	485
2918591816	389	99.73	1	359	1	364	8.9e-74	243.2	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
2918591817	362	99.45	3	362	2	364	4.0e-85	280.6	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
2918591818	768	95.23	1	768	38	795	0.0e+00	666.1	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
2918591819	315	96.92	13	315	3	317	3.7e-25	82.5	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918591820	340	97.89	4	338	5	328	2.4e-123	406.1	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
2918591821	276	96.92	18	276	4	255	2.8e-85	280.1	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
2918591822	144	27.54	5	116	103	159	1.4e-04	15.9	COG2915	Regulator of phage lambda lysogenization HflD, binds to CII and stimulates its degradation	207
2918591823	123	53.62	8	66	19	55	4.8e-05	17	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918591824	220	96.92	6	208	4	192	3.9e-80	262.4	COG0194	Guanylate kinase	191
2918591825	295	99.66	2	295	2	290	5.8e-102	335.6	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
2918591826	406	97.97	49	379	6	342	4.8e-116	381.8	COG1559	Cell division protein YceG, involved in septum cleavage	342
2918591828	420	99.52	1	419	2	413	0.0e+00	547.4	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918591829	78	97.53	1	78	3	81	2.5e-29	95.8	COG0236	Acyl carrier protein	80
2918591830	245	99.25	2	244	2	267	9.1e-76	249.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918591831	314	94.41	1	310	4	324	1.5e-82	271.7	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
2918591832	347	98.75	1	347	1	316	9.6e-111	364.2	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918591833	170	97.65	1	169	1	166	1.5e-25	83.8	COG4283	Uncharacterized protein	170
2918591834	153	96.43	2	113	3	110	5.7e-40	130.1	COG0360	Ribosomal protein S6	112
2918591835	82	93.67	2	77	6	79	6.7e-32	104.4	COG0238	Ribosomal protein S18	75
2918591837	191	99.32	1	148	1	147	7.5e-53	173	COG0359	Ribosomal protein L9	148
2918591838	355	96.31	1	355	13	351	8.3e-113	371	COG1566	Multidrug resistance efflux pump	352
2918591839	582	71.28	57	332	8	280	4.7e-11	37.5	COG0477	MFS family permease	338
2918591840	151	96.99	7	143	4	132	1.7e-27	90.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918591841	498	99.77	19	489	1	435	0.0e+00	503.9	COG0305	Replicative DNA helicase	435
2918591842	100	98	1	100	1	98	1.2e-35	116.4	COG4541	Uncharacterized membrane protein	100
2918591843	234	93.31	1	233	10	232	1.8e-72	238.1	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
2918591844	285	74.24	170	285	27	124	4.0e-30	96.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918591845	391	99.18	18	388	3	363	2.4e-121	399.4	COG0787	Alanine racemase	360
2918591846	84	76.4	1	83	6	73	3.7e-12	41.4	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
2918591847	76	53.54	1	75	1	53	3.1e-08	27.6	COG3668	Plasmid stabilization system protein ParE	98
2918591848	468	96.71	1	454	1	441	0.0e+00	640.6	COG1066	Predicted ATP-dependent serine protease	456
2918591849	195	93.41	3	182	1	170	3.7e-54	177.8	COG1286	Uncharacterized membrane protein, required for colicin V production	182
2918591850	502	97.66	24	496	2	460	0.0e+00	644.7	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
2918591851	246	97.01	3	241	2	261	3.7e-55	181.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918591852	461	98.92	4	459	2	461	0.0e+00	553.8	COG0215	Cysteinyl-tRNA synthetase	464
2918591853	122	86.05	1	122	14	124	8.7e-42	136.7	COG2852	Very-short-patch-repair endonuclease	129
2918591854	157	95.56	1	129	3	131	5.5e-41	133.9	COG3791	Uncharacterized conserved protein	133
2918591855	152	94.81	2	131	4	131	2.0e-38	125.7	COG3791	Uncharacterized conserved protein	133
2918591856	318	92.88	17	317	4	277	7.0e-44	145	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918591857	302	97.29	9	302	6	292	1.1e-108	357.4	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
2918591858	586	96.68	30	575	18	628	5.7e-108	355.5	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2918591859	181	78.05	1	174	36	195	6.3e-60	196.6	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2918591860	668	87.5	64	174	9	99	4.7e-05	16.3	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2918591860	668	99.65	291	656	1	285	1.9e-75	248.8	COG1652	Nucleoid-associated protein YgaU, contains BON and LysM domains	269
2918591861	628	100	103	598	1	497	0.0e+00	845.2	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
2918591862	232	93.41	1	222	16	256	9.4e-60	196.1	COG0688	Phosphatidylserine decarboxylase	239
2918591863	289	97.89	25	267	5	236	4.8e-77	253.4	COG1183	Phosphatidylserine synthase	234
2918591865	430	96.09	1	418	16	433	1.3e-120	397.4	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918591866	253	99.12	1	235	1	224	3.0e-81	266.4	COG2135	Putative SOS response-associated peptidase YedK	226
2918591867	107	97.25	1	107	2	107	1.1e-45	148.7	COG1742	Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily	109
2918591868	138	84.25	1	138	12	134	5.8e-30	98.8	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2918591869	145	100	6	145	1	128	2.5e-57	186.9	COG5451	Predicted secreted protein	128
2918591872	301	93.83	14	295	16	304	4.8e-73	236.9	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
2918591873	207	96.91	17	204	1	188	1.9e-45	149.7	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
2918591874	172	93.02	1	161	13	172	1.5e-70	230.6	COG5350	Predicted protein tyrosine phosphatase	172
2918591875	273	85.67	5	271	21	313	3.3e-65	214.7	COG0668	Small-conductance mechanosensitive channel	316
2918591876	228	97.06	23	228	7	204	9.6e-93	303.9	COG3443	Periplasmic Zn/Cd-binding protein ZinT	193
2918591877	272	94.57	13	269	12	255	1.5e-74	245	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918591878	262	98.01	2	262	2	247	3.6e-87	286.5	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918591879	340	96.12	1	339	8	329	1.5e-42	140.5	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918591880	519	98.09	316	519	2	206	1.5e-57	188.7	COG0400	Predicted esterase	207
2918591880	519	99.32	5	268	2	146	1.4e-31	105.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918591881	923	99.04	1	923	2	927	0.0e+00	1122.8	COG5373	Uncharacterized membrane protein	931
2918591882	214	90.13	2	214	19	219	3.5e-54	178.2	COG1418	HD superfamily phosphodieaserase, includes HD domain of RNase Y	222
2918591883	280	99.26	1	276	3	270	4.2e-99	325.7	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
2918591884	244	49.1	4	241	44	180	1.7e-21	71.5	COG0500	SAM-dependent methyltransferase	257
2918591885	404	48.83	5	208	8	194	6.2e-25	50.1	COG0477	MFS family permease	338
2918591885	404	49.87	213	403	3	193	6.2e-25	39	COG0477	MFS family permease	338
2918591886	259	97.62	1	240	2	247	2.1e-59	195.3	COG1381	Recombinational DNA repair protein (RecF pathway)	251
2918591887	125	34.91	4	119	2	82	6.7e-10	33.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918591888	250	95.87	18	230	2	210	2.0e-34	113.3	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918591889	313	98.32	15	311	4	296	1.2e-120	396.5	COG1159	GTPase Era, involved in 16S rRNA processing	298
2918591890	239	96.19	7	235	7	233	3.3e-71	233.5	COG0571	dsRNA-specific ribonuclease	235
2918591891	248	89.2	4	238	9	165	5.5e-36	113.6	COG0681	Signal peptidase I	166
2918591892	134	98.43	1	131	1	125	3.7e-42	138	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
2918591893	192	99.46	1	185	1	183	6.3e-78	255	COG3216	Uncharacterized conserved protein, DUF2062 family	184
2918591895	744	99.17	1	742	6	723	0.0e+00	892.9	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2918591896	130	100	1	72	1	74	1.0e-26	86	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
2918591897	189	98.44	1	185	1	189	1.2e-59	196.2	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
2918591898	499	90.82	44	485	39	424	3.6e-98	324	COG0840	Methyl-accepting chemotaxis protein	408
2918591899	160	95.42	7	160	5	150	1.4e-66	217.3	COG0691	tmRNA-binding protein	153
2918591900	294	97.66	1	294	4	295	3.0e-116	381.8	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918591901	690	99.67	386	683	1	302	1.6e-64	213.2	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2918591906	113	84.62	1	98	11	98	4.7e-05	18.1	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2918591908	266	99.22	1	255	2	254	5.0e-110	361.2	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
2918591909	405	92.56	5	404	2	399	2.3e-85	281.9	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918591911	370	96.95	6	369	9	358	1.3e-89	294.9	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2918591912	87	23.26	8	87	130	206	1.9e-11	38.5	COG0790	TPR repeat	292
2918591913	112	76.36	1	112	39	164	5.1e-38	125	COG4731	Uncharacterized conserved protein, DUF2147 family	162
2918591914	198	11.33	1	42	91	124	2.1e-08	15.3	COG2074	2-phosphoglycerate kinase	299
2918591914	198	36	57	195	167	274	2.1e-08	11.4	COG2074	2-phosphoglycerate kinase	299
2918591917	501	99.58	221	480	1	236	7.6e-67	219.3	COG0775	Nucleoside phosphorylase	234
2918591918	69	73.81	1	68	15	76	4.5e-18	59.7	COG5450	Transcription regulator of the Arc/MetJ class	84
2918591919	156	96.5	1	154	5	142	1.6e-40	133	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2918591920	457	98.43	7	455	5	444	0.0e+00	521.2	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918591921	302	97.68	1	301	3	297	4.5e-70	230.3	COG1597	Diacylglycerol kinase family enzyme	301
2918591922	414	97.47	24	413	10	394	9.2e-117	384.3	COG2814	Predicted arabinose efflux permease, MFS family	394
2918591923	457	93.39	7	456	29	452	0.0e+00	485.4	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
2918591924	278	98.53	1	272	3	271	7.6e-88	288.9	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
2918591925	129	86.67	2	125	9	112	1.2e-43	142	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2918591926	338	98.49	3	337	5	330	5.5e-81	266.8	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918591927	246	86.06	7	243	35	250	1.1e-37	123.9	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918591928	554	54.79	484	545	17	56	3.6e-05	17.6	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2918591928	554	99.75	12	468	2	407	0.0e+00	449.7	COG0644	Dehydrogenase (flavoprotein)	396
2918591930	306	95.22	1	306	16	314	0.0e+00	468.4	COG3965	Predicted Co/Zn/Cd cation transporter, cation efflux family	314
2918591931	262	98.13	3	259	4	266	5.0e-55	181.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918591932	325	96.17	144	321	8	183	1.5e-46	152.8	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918591933	432	71.12	1	430	5	435	5.6e-73	240.2	COG0443	Molecular chaperone DnaK (HSP70)	579
2918591934	299	98.02	107	299	4	201	4.8e-49	160.6	COG1573	Uracil-DNA glycosylase	202
2918591936	298	92.36	3	289	21	298	4.6e-33	109.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918591937	882	99.54	1	875	4	866	0.0e+00	922.6	COG0308	Aminopeptidase N	859
2918591938	106	79.03	1	106	21	118	1.2e-16	55.6	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918591939	778	69.29	405	773	116	388	7.8e-75	247.4	COG0642	Signal transduction histidine kinase	336
2918591941	989	99.17	9	987	8	962	0.0e+00	1178.7	COG1391	Glutamine synthetase adenylyltransferase	963
2918591942	285	98.45	31	285	5	258	8.5e-77	252.6	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
2918591943	141	92.7	9	141	10	136	1.1e-41	136.7	COG3011	Predicted thiol-disulfide oxidoreductase YuxK, DCC family	137
2918591944	472	79.44	118	471	63	375	3.3e-55	182.8	COG0642	Signal transduction histidine kinase	336
2918591945	252	99.14	28	252	1	230	2.2e-78	257.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918591946	522	20.55	419	521	280	354	0.0e+00	30.9	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918591946	522	92.6	10	415	26	363	0.0e+00	406.2	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918591947	155	96.08	3	155	5	151	4.7e-56	182.7	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
2918591948	663	99.23	1	654	1	641	0.0e+00	864.2	COG1138	Cytochrome c biogenesis factor	648
2918591949	170	96.73	1	154	1	148	5.4e-58	189.2	COG2332	Cytochrome c-type biogenesis protein CcmE	153
2918591950	387	26.99	278	385	134	211	1.8e-87	24.1	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
2918591950	387	96.89	1	282	2	281	1.8e-87	269	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
2918591951	154	98.53	27	154	3	136	1.5e-52	171.7	COG4520	Surface antigen	136
2918591952	466	86.8	104	465	46	387	1.2e-32	108.2	COG0642	Signal transduction histidine kinase	336
2918591953	223	99.14	1	220	1	230	1.9e-84	277.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918591958	144	48.19	1	139	128	247	3.8e-24	80.8	COG0791	Cell wall-associated hydrolase, NlpC family	197
2918591959	294	100	1	292	1	289	0.0e+00	456.6	COG5449	Uncharacterized protein	225
2918591960	212	99.46	27	212	1	183	1.3e-87	286.5	COG5448	Uncharacterized protein	184
2918591961	200	21.78	3	200	688	883	1.7e-48	159.7	COG5281	Phage-related minor tail protein	833
2918591964	135	98.55	1	135	1	136	1.9e-60	197.1	COG5437	Predicted secreted protein	138
2918591965	399	96.46	2	399	14	394	2.7e-16	53.3	COG2814	Predicted arabinose efflux permease, MFS family	394
2918591967	111	98.17	4	111	2	108	1.3e-38	125.9	COG5614	Bacteriophage head-tail adaptor	109
2918591969	422	99.05	1	422	3	420	0.0e+00	575.9	COG4653	Predicted phage phi-C31 gp36 major capsid-like protein	422
2918591970	202	97.94	1	196	4	193	1.3e-53	175.4	COG3740	Phage head maturation protease	194
2918591972	388	95.06	6	388	2	386	3.3e-130	428.8	COG4695	Phage portal protein BeeE	398
2918591973	107	38.38	4	100	47	84	3.2e-04	13.3	COG1359	Quinol monooxygenase YgiN	100
2918591976	419	99.52	1	419	3	418	0.0e+00	754.6	COG5323	Large terminase phage packaging protein	410
2918591978	553	93.37	1	550	38	586	0.0e+00	905.5	COG4425	Uncharacterized membrane protein	588
2918591979	279	97.83	3	271	2	271	2.9e-49	162.3	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2918591980	124	92.5	2	121	8	118	4.3e-42	136.9	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2918591981	143	91.77	1	143	5	149	1.8e-32	107.1	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918591982	366	98.45	1	366	1	382	2.2e-108	357.2	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
2918591983	487	98.59	1	487	8	497	0.0e+00	629.2	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
2918591984	571	94.77	71	571	26	496	3.3e-106	350.5	COG1621	Sucrose-6-phosphate hydrolase SacC, GH32 family	486
2918591985	57	22.01	15	57	4	38	1.2e-03	13.1	COG1580	Flagellar basal body-associated protein FliL	159
2918591986	465	47.78	267	464	8	190	2.1e-23	8.7	COG0477	MFS family permease	338
2918591986	465	81.72	12	333	10	322	2.1e-23	71.8	COG0477	MFS family permease	338
2918591988	121	91.92	1	111	4	94	2.4e-09	32.1	COG3668	Plasmid stabilization system protein ParE	98
2918591989	89	93.26	1	85	2	84	7.7e-16	53	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
2918591990	66	91.78	1	65	4	70	3.2e-11	37.9	COG2608	Copper chaperone CopZ	71
2918591991	140	95.45	1	119	2	127	3.7e-34	112.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918591992	232	28.45	1	228	522	729	3.7e-90	297.9	COG2217	Cation transport ATPase	713
2918591995	91	97.75	1	88	1	87	2.1e-30	99.3	COG3077	Antitoxin component of the RelBE or YafQ-DinJ toxin-antitoxin module	88
2918591996	111	96.7	19	110	4	91	7.6e-35	113.6	COG3041	mRNA-degrading endonuclease (mRNA interferase) YafQ, toxin component of the YafQ-DinJ toxin-antitoxin module	91
2918591997	274	91.76	6	272	20	253	4.4e-90	295.6	COG2602	Beta-lactamase class D	254
2918591998	159	95.42	1	150	6	151	1.5e-69	227.2	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
2918591999	730	94.39	42	721	14	686	0.0e+00	669.7	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2918592000	299	98.34	2	299	2	297	1.6e-39	130.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918592001	202	98.51	2	202	2	200	6.4e-77	252.2	COG1279	Arginine exporter protein ArgO	202
2918592002	195	98.97	1	194	2	193	4.1e-92	301.9	COG5402	Uncharacterized protein	194
2918592003	182	97.25	2	181	3	179	7.8e-56	183.1	COG5436	Uncharacterized membrane protein	182
2918592005	319	87.64	1	319	25	343	4.1e-107	353.1	COG5330	Uncharacterized conserved protein, DUF2336 family	364
2918592006	117	99.13	1	116	1	114	1.1e-53	174.7	COG5447	Uncharacterized protein	115
2918592007	280	28.99	199	279	57	125	1.3e-21	28.6	COG3409	Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases	185
2918592007	280	49.58	69	213	12	129	1.3e-21	44	COG3409	Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases	185
2918592008	510	75.38	10	468	92	388	1.7e-73	241.7	COG0642	Signal transduction histidine kinase	336
2918592010	138	90.28	1	138	11	140	2.1e-55	180.8	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
2918592013	142	93.24	1	142	4	141	5.3e-71	231.9	COG4957	Predicted transcriptional regulator	148
2918592014	110	95.58	3	110	2	109	3.1e-37	121.6	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
2918592015	106	76.4	1	71	19	86	8.4e-27	87.7	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
2918592016	159	98.73	1	158	3	158	3.6e-54	177.6	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
2918592017	525	99.01	24	523	2	502	6.6e-129	425	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
2918592018	125	98.25	1	115	1	112	2.8e-37	121.5	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
2918592019	139	81.21	1	135	21	154	1.4e-16	55.2	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
2918592020	789	94.17	9	648	2	582	0.0e+00	560.7	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2918592021	135	89.36	8	135	3	128	2.8e-61	199.8	COG0229	Peptide methionine sulfoxide reductase MsrB	140
2918592022	208	99.52	1	206	1	207	5.6e-46	150.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918592023	165	96.45	2	165	2	164	8.6e-66	215.5	COG1247	L-amino acid N-acyltransferase YncA	169
2918592024	222	92.31	1	218	17	232	2.2e-66	217.8	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
2918592025	106	85.83	1	106	7	109	2.8e-23	77.3	COG1734	RNA polymerase-binding transcription factor DksA	120
2918592026	136	95.6	1	136	4	155	2.7e-23	78	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918592027	286	99.27	5	286	2	272	9.7e-108	354.1	COG2514	Catechol-2,3-dioxygenase	265
2918592028	398	94.17	50	397	10	348	1.2e-49	163.6	COG0628	Predicted PurR-regulated permease PerM	355
2918592029	359	97.02	184	348	5	167	1.5e-52	172.6	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2918592029	359	98.41	2	188	1	186	1.8e-67	221	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
2918592030	241	73.13	10	235	61	256	3.9e-30	99.4	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918592031	302	98.66	1	300	2	296	1.8e-82	270.8	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918592033	699	99.71	5	697	2	682	0.0e+00	1001.1	COG1770	Protease II	682
2918592034	336	100	1	332	1	305	6.7e-91	298.9	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
2918592035	302	96.56	12	302	6	286	1.5e-113	373.5	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
2918592036	368	85.57	1	366	2	333	0.0e+00	494.6	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
2918592038	339	98.33	2	339	4	297	4.0e-91	300	COG1230	Co/Zn/Cd efflux system component	296
2918592039	90	98.88	1	89	1	88	8.1e-29	94.4	COG1937	DNA-binding transcriptional regulator, FrmR family	89
2918592041	137	95.45	2	120	2	127	1.1e-33	110.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918592042	162	79.01	21	157	31	158	1.8e-16	54.9	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918592043	188	95.92	1	171	3	190	2.3e-19	64.3	COG0693	Putative intracellular protease/amidase	188
2918592045	237	98.75	1	237	1	237	2.0e-115	378.8	COG5446	Uncharacterized membrane protein, predicted cobalt tansporter CbtA	233
2918592046	60	40.17	2	58	4	50	3.3e-04	15.1	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
2918592048	306	13.41	13	114	63	84	1.9e-33	6.7	COG2010	Cytochrome c, mono- and diheme variants	150
2918592048	306	99.39	127	303	1	163	1.9e-33	104.3	COG2010	Cytochrome c, mono- and diheme variants	150
2918592049	144	99.32	1	144	2	147	1.5e-59	194.9	COG3909	Cytochrome c556	147
2918592050	209	98.56	2	208	3	207	3.3e-50	164.6	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918592051	239	73.8	1	238	4	234	4.4e-79	260.6	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2918592052	289	12.41	23	104	39	87	2.6e-11	4.7	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2918592052	289	27.59	135	255	286	394	2.6e-11	32.5	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2918592053	200	98.54	1	200	2	203	1.0e-74	245.4	COG0605	Superoxide dismutase	204
2918592055	180	97.63	8	176	3	167	8.4e-62	202.5	COG1247	L-amino acid N-acyltransferase YncA	169
2918592056	295	97.67	4	295	1	294	5.4e-63	208	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918592057	786	28.94	30	435	38	160	1.8e-103	13.8	COG0840	Methyl-accepting chemotaxis protein	408
2918592057	786	77.88	421	730	95	425	1.8e-103	330.4	COG0840	Methyl-accepting chemotaxis protein	408
2918592058	293	98.25	10	290	3	282	9.2e-70	230	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2918592059	256	99.22	1	256	1	255	1.7e-116	382.9	COG4106	Trans-aconitate methyltransferase	257
2918592060	122	84.25	5	119	7	129	1.4e-08	30.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918592061	235	73.8	1	235	5	235	3.6e-74	244.6	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2918592062	308	96.41	1	306	1	295	2.6e-97	320	COG3781	Predicted membrane chloride channel, bestrophin family	306
2918592063	275	96.81	1	275	7	279	8.7e-96	314.6	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2918592064	203	95.19	1	203	9	206	1.0e-54	179.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918592065	268	86.36	147	268	12	125	4.0e-27	88.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918592066	252	100	1	249	1	247	9.1e-109	357.1	COG3967	Short-chain dehydrogenase involved in D-alanine esterification of teichoic acids	245
2918592067	143	89.17	11	138	12	118	3.2e-37	121.2	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2918592069	523	99.07	23	520	5	536	3.0e-97	321.1	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
2918592070	116	36.29	12	110	50	94	1.2e-03	13.3	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
2918592071	158	87.9	3	151	14	122	5.3e-33	108.2	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918592072	240	96.34	1	240	6	242	3.6e-89	293.1	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2918592073	298	97.01	3	298	1	292	4.7e-66	218	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918592074	259	94.49	1	125	5	124	1.6e-73	100.3	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2918592074	259	98.43	134	259	2	126	1.6e-73	140.7	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2918592076	242	96.67	1	235	8	239	1.9e-107	352.8	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
2918592077	134	92.48	12	133	2	124	3.2e-22	73.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918592078	140	99.19	1	123	1	122	2.8e-44	144.6	COG3795	Uncharacterized conserved protein	123
2918592079	418	13.27	336	414	448	518	2.2e-96	79.6	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918592079	418	68.6	1	343	1	367	2.2e-96	238.1	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918592082	140	97.2	1	140	4	142	1.7e-50	165.4	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2918592083	152	94.74	27	151	4	129	1.2e-26	87.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918592084	241	81.4	6	241	44	240	1.7e-73	242.3	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2918592085	302	80.17	87	302	46	239	1.5e-67	222.5	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2918592086	912	11.63	13	115	2	86	0.0e+00	32.8	COG2217	Cation transport ATPase	713
2918592086	912	99.18	117	909	3	727	0.0e+00	766.7	COG2217	Cation transport ATPase	713
2918592087	260	77.71	2	260	18	289	1.9e-66	219.2	COG3774	Mannosyltransferase OCH1 or related enzyme	347
2918592088	321	41.82	16	320	370	650	4.3e-48	158.9	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
2918592089	541	97.56	58	537	11	490	1.8e-117	387.5	COG1793	ATP-dependent DNA ligase	444
2918592090	338	96.57	1	337	13	434	4.7e-70	230.4	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
2918592091	509	54.05	265	507	5	211	2.5e-39	11.3	COG0477	MFS family permease	338
2918592091	509	72.06	16	274	4	279	2.5e-39	124.4	COG0477	MFS family permease	338
2918592092	171	84.21	13	155	16	127	1.5e-20	67.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918592093	219	94.42	2	219	2	204	1.6e-44	144.2	COG0625	Glutathione S-transferase	211
2918592094	206	98.6	2	206	2	213	2.3e-40	133.2	COG0625	Glutathione S-transferase	211
2918592095	332	97.64	1	332	8	338	0.0e+00	577.9	COG4448	L-asparaginase II	339
2918592098	99	92.93	1	99	1	92	1.5e-13	45.7	COG3668	Plasmid stabilization system protein ParE	98
2918592099	549	97.36	1	542	7	559	0.0e+00	511.9	COG2303	Choline dehydrogenase or related flavoprotein	542
2918592100	493	99.16	13	488	2	476	0.0e+00	579.6	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918592101	211	83.25	1	199	12	185	3.2e-21	71.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918592102	78	65.17	1	77	2	59	4.9e-16	53.6	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
2918592103	600	78.14	396	590	13	155	7.6e-25	81.5	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918592103	600	93	3	267	5	243	6.1e-60	196.1	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918592103	600	93.87	267	403	10	162	3.4e-05	17.8	COG0517	CBS domain	117
2918592104	337	100	11	336	1	331	3.9e-109	359.5	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918592105	346	99.71	1	346	1	349	0.0e+00	474.7	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
2918592106	289	95.12	4	289	10	282	0.0e+00	459.5	COG4208	ABC-type sulfate transport system, permease component	287
2918592107	285	98.54	10	283	4	273	1.1e-111	366.5	COG0555	ABC-type sulfate transport system, permease component	274
2918592108	341	91.98	2	341	26	346	0.0e+00	546	COG1613	ABC-type sulfate transport system, periplasmic component	348
2918592109	146	89.33	1	145	2	135	4.4e-46	151	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918592110	253	89.55	2	249	14	253	2.4e-62	205	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2918592111	317	98.88	4	317	4	268	3.6e-84	276.7	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2918592112	494	95.62	25	459	3	417	0.0e+00	607.3	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
2918592115	571	99.53	51	524	2	429	0.0e+00	503.5	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
2918592116	93	95.51	3	91	3	87	1.7e-23	77.7	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
2918592117	103	92.93	2	103	4	95	3.3e-22	73.4	COG3668	Plasmid stabilization system protein ParE	98
2918592119	302	85	15	294	19	239	6.0e-41	135.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918592121	454	98.56	12	447	4	415	0.0e+00	432.4	COG1301	Na+/H+-dicarboxylate symporter	415
2918592125	908	99.62	5	885	2	785	0.0e+00	812.1	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
2918592126	325	99.27	40	324	2	272	2.1e-105	346.4	COG2514	Catechol-2,3-dioxygenase	265
2918592127	1155	99.91	1	1152	1	1167	0.0e+00	956.3	COG1196	Chromosome segregation ATPase	1163
2918592128	226	97.59	6	226	5	247	1.8e-56	185.9	COG1651	Protein-disulfide isomerase	244
2918592129	173	88.4	2	169	22	181	1.1e-81	267.5	COG5389	Uncharacterized protein	181
2918592131	370	97.18	2	360	9	352	6.1e-128	421.6	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
2918592132	203	86.15	1	199	1	199	6.7e-35	115.5	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918592133	98	93.94	3	98	4	96	1.2e-19	65.2	COG3668	Plasmid stabilization system protein ParE	98
2918592134	83	96.63	1	83	2	87	3.9e-19	63.7	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
2918592135	381	95.05	15	302	14	301	3.8e-99	326.1	COG0863	DNA modification methylase	302
2918592137	170	99.26	1	136	2	135	2.5e-53	174.5	COG3543	Uncharacterized protein	135
2918592138	226	92.24	1	221	10	223	1.9e-57	188.8	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918592139	229	98.19	3	223	2	218	2.8e-57	188.5	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2918592140	104	89.47	2	103	6	90	3.7e-29	95.7	COG3514	Uncharacterized conserved protein, DUF4415 family	93
2918592142	465	99.52	1	460	2	418	0.0e+00	486	COG0498	Threonine synthase	411
2918592143	434	95.88	1	417	16	434	1.4e-123	407.2	COG0612	Predicted Zn-dependent peptidase	438
2918592144	199	96.79	8	194	3	183	4.5e-44	145.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918592145	971	62.59	500	967	227	641	8.3e-96	315.5	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918592145	971	78.1	12	531	52	240	5.0e-15	49.6	COG2202	PAS domain	232
2918592146	364	97.71	1	364	1	341	0.0e+00	563.4	COG4307	Uncharacterized protein	349
2918592147	63	92.54	1	63	1	62	8.3e-24	78	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2918592148	201	98.97	3	201	3	194	3.6e-72	236.4	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
2918592149	282	99.64	2	280	2	275	2.4e-92	304	COG4233	Thiol-disulfide interchange protein, contains DsbC and DsbD domains	273
2918592150	161	100	1	161	1	166	1.0e-70	230.9	COG0678	Peroxiredoxin	165
2918592152	146	94.87	1	146	1	148	5.2e-65	212.7	COG0328	Ribonuclease HI	154
2918592153	322	97.91	1	322	6	333	3.3e-99	326.3	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2918592154	348	95.93	9	307	3	285	1.1e-115	380.1	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
2918592155	250	94.49	4	250	3	242	6.1e-88	288.8	COG3346	Cytochrome oxidase assembly protein ShyY1	252
2918592156	128	94.44	1	125	7	125	8.1e-57	185	COG5349	Uncharacterized conserved protein, DUF983 family	126
2918592157	291	97.18	64	285	5	211	2.2e-71	233.7	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918592158	205	97.54	1	201	4	201	1.2e-87	287	COG3175	Cytochrome c oxidase assembly protein Cox11	195
2918592160	317	94.14	2	311	14	302	2.2e-118	389.5	COG0109	Polyprenyltransferase (heme O synthase)	304
2918592161	566	89.81	26	566	8	518	0.0e+00	776.7	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2918592162	298	94.09	10	296	3	241	1.0e-77	255	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2918592163	174	93.92	1	174	9	178	1.5e-58	191.9	COG5342	Invasion protein IalB, involved in pathogenesis	181
2918592164	471	98.9	12	469	5	455	0.0e+00	507.7	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2918592165	145	80.82	8	143	7	124	4.2e-10	35.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918592166	221	95.93	5	221	2	213	3.2e-50	165.5	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2918592168	101	82.52	1	100	5	89	4.9e-20	66.1	COG1694	NTP pyrophosphatase, house-cleaning of non-canonical NTPs	102
2918592169	259	95.75	13	254	3	250	4.5e-23	76.2	COG0730	Uncharacterized membrane protein YfcA	258
2918592170	206	93.93	1	206	14	214	1.5e-93	306.6	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
2918592172	371	36.1	204	369	219	357	1.6e-47	65.6	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2918592172	371	39.48	1	185	4	155	1.6e-47	88.8	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2918592173	272	98.46	5	265	2	256	5.2e-125	410.4	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
2918592174	197	89.95	2	197	5	192	2.3e-53	175.3	COG0406	Broad specificity phosphatase PhoE	208
2918592175	86	62.04	1	84	41	107	1.1e-05	15.5	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
2918592176	365	96.49	2	365	2	358	0.0e+00	506.3	COG0082	Chorismate synthase	369
2918592177	366	86.73	206	366	2	171	1.1e-36	120.4	COG0807	GTP cyclohydrolase II	193
2918592177	366	98.52	3	206	3	202	7.6e-87	284.2	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
2918592178	404	96.76	1	402	1	388	0.0e+00	556.8	COG3214	Uncharacterized conserved protein YcaQ, contains winged helix DNA-binding domain	400
2918592179	226	91.56	2	224	14	230	3.3e-57	187.7	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
2918592180	210	85.13	1	208	6	234	1.6e-25	81.1	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
2918592181	187	94.59	1	186	5	179	2.7e-53	174.7	COG1268	Biotin transporter BioY	184
2918592182	311	90.49	1	311	2	315	7.7e-111	364.9	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2918592183	84	92.59	1	83	3	77	1.2e-28	93.3	COG1722	Exonuclease VII small subunit	81
2918592184	307	99.29	13	292	3	280	1.9e-97	320.6	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2918592185	636	99.68	3	630	2	626	0.0e+00	885.2	COG1154	Deoxyxylulose-5-phosphate synthase	627
2918592187	263	45.38	7	192	2	60	3.1e-11	38.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918592188	104	95.96	1	99	3	97	9.8e-24	77.7	COG1359	Quinol monooxygenase YgiN	100
2918592189	127	98.44	1	127	1	126	2.2e-55	180.5	COG3603	Uncharacterized protein	128
2918592190	150	93.67	1	150	6	153	4.6e-36	118.8	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918592191	320	45.68	12	106	39	112	4.6e-08	17.3	COG0700	Spore maturation protein SpmB (function unknown)	162
2918592191	320	50	174	305	38	118	4.6e-08	15.5	COG0700	Spore maturation protein SpmB (function unknown)	162
2918592192	673	24.94	60	298	36	141	6.8e-113	33.4	COG0840	Methyl-accepting chemotaxis protein	408
2918592192	673	75.53	292	593	104	424	6.8e-113	344	COG0840	Methyl-accepting chemotaxis protein	408
2918592193	250	98.37	6	250	2	242	1.2e-94	310.6	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
2918592194	416	99.08	1	410	5	436	1.0e-102	338.8	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
2918592196	252	96.6	1	252	3	258	1.0e-60	199.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918592197	594	96.99	12	463	7	393	6.4e-111	365.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918592198	331	90.85	10	331	29	326	2.6e-49	162.2	COG0598	Mg2+ and Co2+ transporter CorA	322
2918592201	360	99.63	16	300	1	267	5.1e-90	295.9	COG1018	Ferredoxin-NADP reductase	266
2918592202	436	98.94	37	432	2	373	2.5e-122	403.2	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918592204	325	97.17	2	212	5	210	1.9e-72	236.9	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
2918592205	477	99.36	14	477	2	467	1.3e-122	404.5	COG0277	FAD/FMN-containing dehydrogenase	459
2918592207	385	96.63	68	372	2	288	4.9e-109	358.4	COG1533	DNA repair photolyase	297
2918592208	223	93.07	41	223	2	189	1.1e-62	206.2	COG0164	Ribonuclease HII	199
2918592209	465	85.79	257	464	8	176	1.3e-70	45.9	COG2059	Chromate transport protein ChrA	195
2918592209	465	89.34	15	240	6	181	1.3e-70	192.5	COG2059	Chromate transport protein ChrA	195
2918592210	270	80.7	2	106	13	104	4.7e-10	33.4	COG0607	Rhodanese-related sulfurtransferase	110
2918592210	270	99.31	117	261	2	145	5.9e-66	215.6	COG4275	Uncharacterized protein	143
2918592211	161	95.65	1	159	7	160	1.2e-37	123.5	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2918592212	213	95.03	55	212	3	155	3.2e-38	125.1	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2918592213	75	91.25	1	75	7	79	1.7e-21	70.7	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
2918592214	249	97.62	1	248	5	250	5.3e-72	236.7	COG0356	FoF1-type ATP synthase, membrane subunit a	246
2918592215	121	99.14	1	118	1	115	5.8e-49	159.4	COG5336	FoF1-type ATP synthase assembly protein I	116
2918592216	387	99.6	139	387	2	247	5.0e-93	305.8	COG3773	Cell wall hydrolase CwlJ, involved in spore germination	249
2918592217	639	99.2	10	639	5	626	0.0e+00	934.2	COG3158	K+ transporter	627
2918592218	325	90.55	6	325	32	328	1.8e-70	231.7	COG0598	Mg2+ and Co2+ transporter CorA	322
2918592219	376	96.5	37	332	10	285	1.1e-95	314.2	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918592220	407	90.75	1	328	29	332	1.2e-65	216.4	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918592221	246	77.5	178	245	19	80	6.3e-25	79	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918592222	279	98.78	27	271	2	244	5.8e-78	255.6	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918592223	254	99.25	7	254	2	267	6.4e-54	177.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918592224	304	98.69	1	304	2	303	9.4e-124	406.8	COG3734	2-keto-3-deoxy-galactonokinase	306
2918592225	209	95.26	1	209	9	209	2.9e-64	210.8	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
2918592226	295	94.5	2	293	16	307	2.8e-88	290.3	COG3386	Sugar lactone lactonase YvrE	307
2918592227	450	63.95	2	442	221	644	8.4e-121	398.4	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918592228	553	22.31	7	91	121	174	1.0e-14	6.2	COG2202	PAS domain	232
2918592228	553	43.61	300	408	6	63	5.9e-31	8.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918592228	553	83.46	426	548	7	117	5.9e-31	90.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918592228	553	97.93	26	267	2	238	1.0e-14	45.8	COG2202	PAS domain	232
2918592230	613	99.84	1	613	1	644	0.0e+00	656.1	COG0323	DNA mismatch repair ATPase MutL	638
2918592231	73	93.51	1	73	2	73	9.5e-43	138.5	COG3908	Uncharacterized protein	77
2918592232	348	99.11	1	339	2	334	9.4e-111	364.6	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
2918592233	245	98.65	10	243	2	220	1.3e-41	137.5	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918592234	440	99.28	9	422	4	418	0.0e+00	501.9	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
2918592236	268	97.68	5	263	5	257	7.4e-60	196.8	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2918592237	448	99.12	8	448	4	455	2.1e-121	400.2	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2918592238	609	89.24	375	588	18	216	1.3e-30	101.5	COG1226	Voltage-gated potassium channel Kch	212
2918592238	609	98	1	395	4	395	6.9e-106	348.7	COG0475	Kef-type K+ transport system, membrane component KefB	397
2918592239	308	92.16	20	305	9	302	3.6e-71	234.5	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2918592240	185	98.94	1	185	2	187	1.7e-53	175.4	COG0742	16S rRNA G966 N2-methylase RsmD	187
2918592241	652	93.9	51	283	2	232	2.4e-69	227.2	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2918592242	152	96.08	1	147	6	152	2.3e-53	174.8	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2918592244	967	99.68	8	964	2	945	0.0e+00	1093.2	COG0060	Isoleucyl-tRNA synthetase	933
2918592245	326	98.37	4	312	5	306	4.4e-108	355.3	COG0196	FAD synthase	304
2918592246	282	91.11	8	281	3	248	7.8e-67	219.8	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
2918592247	98	96.88	4	98	2	94	8.1e-43	139.1	COG0234	Co-chaperonin GroES (HSP10)	96
2918592248	544	99.09	1	537	1	545	0.0e+00	638.4	COG0459	Chaperonin GroEL (HSP60 family)	524
2918592250	148	91.67	1	146	11	142	8.1e-35	114.8	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918592251	230	73.38	1	230	2	216	2.1e-72	238.4	COG0040	ATP phosphoribosyltransferase	290
2918592252	375	95.65	1	375	17	390	2.0e-115	380.1	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
2918592253	122	97.95	4	118	3	145	1.6e-09	31.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918592254	507	98.84	9	494	3	429	0.0e+00	432.6	COG0124	Histidyl-tRNA synthetase	429
2918592255	77	95	1	77	4	79	3.6e-30	98.5	COG4710	Predicted DNA-binding protein with an HTH domain	80
2918592256	52	45.05	5	52	48	88	3.3e-16	54	COG2026	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system	90
2918592259	124	47.74	4	124	101	195	5.5e-33	109	COG3544	Uncharacterized conserved protein, DUF305 family	190
2918592260	305	97.67	1	300	1	294	1.3e-59	196.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918592261	347	99.1	12	345	3	333	2.2e-99	326.8	COG2855	Uncharacterized membrane protein YadS	334
2918592263	209	98.4	13	201	2	186	4.1e-82	268.8	COG2818	3-methyladenine DNA glycosylase Tag	188
2918592264	259	97.52	1	259	4	239	1.8e-73	242.1	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2918592265	219	96.61	2	219	9	236	2.1e-12	41.5	COG3637	Opacity protein and related surface antigens	199
2918592266	433	99.25	15	426	3	400	5.4e-104	342.7	COG0247	Fe-S oxidoreductase	388
2918592267	404	91.26	1	400	38	465	1.1e-61	203.6	COG0277	FAD/FMN-containing dehydrogenase	459
2918592268	477	99.79	24	474	1	468	7.8e-122	401.9	COG0277	FAD/FMN-containing dehydrogenase	459
2918592269	299	98.01	2	296	2	296	2.2e-80	265.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918592270	424	99.76	1	424	1	423	0.0e+00	799.5	COG4949	Uncharacterized membrane-anchored protein	424
2918592272	257	96.68	6	245	7	239	1.9e-62	205.2	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918592273	445	95.6	20	427	13	403	9.3e-49	161.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918592274	248	27.21	2	103	3	76	1.4e-29	21.7	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
2918592274	248	47.43	83	247	141	269	1.4e-29	75.2	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
2918592275	146	80.23	1	145	12	149	9.6e-16	52.7	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918592276	502	99.44	60	501	3	354	3.6e-121	398.9	COG0306	Phosphate/sulfate permease	326
2918592277	245	99.19	5	243	2	245	7.5e-73	239.2	COG1385	16S rRNA U1498 N3-methylase RsmE	246
2918592278	457	100	1	457	1	456	0.0e+00	770.6	COG3572	Gamma-glutamylcysteine synthetase	456
2918592279	97	60.32	14	77	20	57	2.9e-07	24	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918592280	316	98.01	5	287	1	295	8.1e-64	210.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918592283	317	99.66	19	315	1	289	6.8e-95	311.9	COG0382	4-hydroxybenzoate polyprenyltransferase	289
2918592284	266	100	1	261	1	258	9.7e-85	278.8	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
2918592285	418	98.95	101	384	4	286	3.0e-107	352.3	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2918592286	774	98.85	1	774	9	781	0.0e+00	1087.9	COG2183	Transcriptional accessory protein Tex/SPT6	780
2918592287	423	99.77	1	423	1	428	0.0e+00	596.3	COG0151	Phosphoribosylamine-glycine ligase	428
2918592289	607	19.53	48	266	63	145	1.4e-92	14.2	COG0840	Methyl-accepting chemotaxis protein	408
2918592289	607	77.88	261	590	95	425	1.4e-92	291.1	COG0840	Methyl-accepting chemotaxis protein	408
2918592290	164	98.08	3	162	2	154	2.6e-57	187.3	COG1683	Uncharacterized conserved protein YbbK, DUF523 family	156
2918592291	717	99.57	1	717	3	690	0.0e+00	870.1	COG0751	Glycyl-tRNA synthetase, beta subunit	691
2918592292	645	12.23	363	645	241	274	2.1e-04	14.4	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
2918592293	425	98.6	1	414	5	428	9.8e-123	398.4	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
2918592294	183	97.84	1	181	5	185	1.3e-71	234.3	COG1704	Uncharacterized conserved protein	185
2918592296	317	96.31	8	316	2	288	0.0e+00	520.5	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
2918592297	64	43.97	1	64	50	111	5.0e-09	31.2	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
2918592298	288	74.06	3	285	53	289	6.3e-77	253.5	COG0616	Periplasmic serine protease, ClpP class	317
2918592299	266	96.77	4	256	8	247	8.6e-73	238.8	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
2918592301	338	98.48	18	338	5	327	2.1e-103	340.3	COG0142	Geranylgeranyl pyrophosphate synthase	322
2918592302	614	41.85	435	596	191	344	1.7e-30	47.4	COG0457	Tetratricopeptide (TPR) repeat	291
2918592302	614	82.61	4	480	55	358	1.7e-30	66.2	COG0457	Tetratricopeptide (TPR) repeat	291
2918592303	294	96.21	10	294	7	285	1.7e-86	284.3	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
2918592304	181	95.29	4	169	6	167	7.7e-63	205.2	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
2918592305	291	98.73	66	291	2	235	2.3e-68	224.5	COG0412	Dienelactone hydrolase	236
2918592306	342	99.12	2	342	2	339	0.0e+00	434.6	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2918592307	139	97.12	1	139	3	137	2.3e-60	197.1	COG5331	Uncharacterized protein	139
2918592308	473	83.03	1	194	31	211	3.5e-98	113.5	COG0516	IMP dehydrogenase/GMP reductase	170
2918592308	473	98.17	241	461	4	217	3.5e-98	214	COG0516	IMP dehydrogenase/GMP reductase	170
2918592309	333	77.31	52	332	19	219	5.1e-34	112.4	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918592310	465	48.83	253	462	8	194	3.8e-36	8.4	COG0477	MFS family permease	338
2918592310	465	89.03	1	290	5	345	3.8e-36	114.4	COG0477	MFS family permease	338
2918592311	246	99.02	25	231	2	204	1.6e-78	257.5	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
2918592314	1261	67.01	868	1261	127	390	1.2e-63	209.5	COG0642	Signal transduction histidine kinase	336
2918592315	554	97.98	7	554	7	539	0.0e+00	478	COG1178	ABC-type Fe3+ transport system, permease component	540
2918592316	270	94.38	1	262	12	263	3.7e-98	322.4	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918592317	302	95.83	3	302	6	281	9.1e-105	344.5	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918592318	385	98.58	20	385	4	351	0.0e+00	443.7	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918592319	365	99.74	1	365	1	377	2.2e-118	390	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918592320	471	81.16	1	81	5	60	6.7e-07	22.6	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2918592320	471	99.7	143	471	2	332	0.0e+00	459.7	COG3800	Predicted transcriptional regulator	332
2918592321	429	37.5	244	424	296	472	0.0e+00	275.9	COG2224	Isocitrate lyase	433
2918592321	429	51.48	10	247	18	260	0.0e+00	350.8	COG2224	Isocitrate lyase	433
2918592323	290	97.67	4	280	3	296	1.0e-34	115.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918592325	393	98.53	2	393	2	402	0.0e+00	513.1	COG2081	Predicted flavoprotein YhiN	408
2918592326	463	98.65	16	462	5	444	0.0e+00	451.4	COG0174	Glutamine synthetase	443
2918592327	428	98.97	29	410	2	385	1.0e-72	240	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918592329	491	98.97	4	490	5	485	0.0e+00	669.4	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
2918592330	232	95.83	3	232	2	231	1.4e-63	209	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
2918592331	606	98.62	4	606	5	574	0.0e+00	668.9	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918592332	454	85.42	11	448	6	456	3.7e-48	158.7	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
2918592334	362	99.71	1	356	1	349	0.0e+00	471	COG3839	ABC-type sugar transport system, ATPase component	338
2918592335	561	98.07	29	535	1	507	0.0e+00	493.6	COG0366	Glycosidase	505
2918592336	386	98.59	3	384	5	283	5.0e-99	325.6	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918592337	337	97.65	44	337	5	295	6.8e-69	226.8	COG1175	ABC-type sugar transport system, permease component	295
2918592338	453	98.19	1	453	4	438	2.3e-47	156.9	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918592339	341	99.4	1	339	2	333	6.6e-94	309.3	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918592340	299	98.59	3	295	2	281	2.4e-114	375.5	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
2918592341	591	97.2	1	449	6	457	5.0e-47	155.2	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918592342	180	75.49	1	180	41	231	3.3e-44	144.7	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
2918592345	185	25.73	64	185	63	106	3.6e-06	20.7	COG3951	Rod binding protein domain	166
2918592346	139	21.87	3	111	106	187	1.8e-03	11.9	COG4585	Signal transduction histidine kinase	365
2918592347	240	90.31	1	240	15	247	4.8e-73	240.2	COG1684	Flagellar biosynthesis protein FliR	258
2918592348	680	97.13	1	680	19	695	0.0e+00	911.9	COG1298	Flagellar biosynthesis pathway, component FlhA	696
2918592349	88	97.75	1	88	1	87	5.1e-32	104.4	COG1987	Flagellar biosynthesis protein FliQ	89
2918592350	156	69.06	1	156	1	154	3.9e-43	142.2	COG1843	Flagellar hook assembly protein FlgD	222
2918592351	149	100	1	148	1	148	4.7e-81	264.3	COG5443	Flagellar biosynthesis regulator FlbT	148
2918592352	114	100	1	114	1	115	3.0e-58	189.4	COG5442	Flagellar biosynthesis regulator FlaF	115
2918592353	367	98.71	4	367	3	385	1.5e-35	117.8	COG1344	Flagellin and related hook-associated protein FlgL	360
2918592354	492	99.83	1	492	1	587	1.5e-106	351.9	COG1256	Flagellar hook-associated protein FlgK	552
2918592355	426	99.79	3	426	2	472	4.4e-109	359.8	COG1749	Flagellar hook protein FlgE	423
2918592356	223	97.84	1	223	3	229	3.2e-37	122.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918592357	188	63.04	2	187	100	290	4.7e-27	89.9	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2918592360	427	99.26	15	426	2	269	6.7e-91	296.4	COG1360	Flagellar motor protein MotB	244
2918592362	430	99.48	2	430	2	387	7.5e-75	247.1	COG1344	Flagellin and related hook-associated protein FlgL	360
2918592364	360	97.25	2	360	2	354	0.0e+00	445.9	COG1377	Flagellar biosynthesis protein FlhB	363
2918592365	347	96.47	7	344	10	337	2.9e-105	346.5	COG1536	Flagellar motor switch protein FliG	339
2918592366	179	69.5	41	173	44	141	1.3e-31	104.5	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
2918592367	317	92.79	1	317	23	331	9.4e-80	262.6	COG1868	Flagellar motor switch protein FliM	332
2918592368	290	98.13	1	285	3	264	3.6e-98	322.2	COG1291	Flagellar motor component MotA	266
2918592370	244	97.74	1	241	1	259	1.6e-68	225.2	COG4786	Flagellar basal body rod protein FlgG	265
2918592371	468	96.83	12	454	4	431	0.0e+00	533.9	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
2918592373	130	97.78	1	130	2	133	5.2e-38	124.9	COG1815	Flagellar basal body rod protein FlgB	133
2918592374	139	97.83	2	136	4	138	4.7e-48	157.3	COG1558	Flagellar basal body rod protein FlgC	137
2918592375	112	87.74	2	112	14	106	1.2e-25	84.5	COG1677	Flagellar hook-basal body complex protein FliE	105
2918592376	262	99.25	1	262	2	264	3.0e-99	326.2	COG4786	Flagellar basal body rod protein FlgG	265
2918592377	146	65	1	145	77	219	4.3e-50	165	COG1261	Flagella basal body P-ring formation protein FlgA	220
2918592378	373	98.36	6	373	6	364	0.0e+00	504.4	COG1706	Flagellar basal body P-ring protein FlgI	365
2918592379	178	89.74	1	178	20	194	1.1e-56	186.6	COG3334	Flagellar motility protein MotE, a chaperone for MotC folding	192
2918592380	239	97.4	4	236	5	229	2.5e-83	273.5	COG2063	Flagellar basal body L-ring protein FlgH	230
2918592381	166	96.86	1	166	5	158	3.3e-11	35.4	COG1580	Flagellar basal body-associated protein FliL	159
2918592382	245	97.59	1	245	7	249	1.1e-95	314.2	COG1338	Flagellar biosynthetic protein FliP	248
2918592383	306	34.28	167	306	256	388	5.7e-67	84.3	COG1344	Flagellin and related hook-associated protein FlgL	360
2918592383	306	46.65	2	184	2	182	5.7e-67	142.2	COG1344	Flagellin and related hook-associated protein FlgL	360
2918592384	321	99.74	2	321	2	388	1.8e-66	213.2	COG1344	Flagellin and related hook-associated protein FlgL	360
2918592385	313	24.23	195	312	295	388	6.6e-67	82.5	COG1344	Flagellin and related hook-associated protein FlgL	360
2918592385	313	50.52	2	204	2	197	6.6e-67	144.6	COG1344	Flagellin and related hook-associated protein FlgL	360
2918592387	88	5.99	2	77	64	119	4.0e-02	6.7	COG5373	Uncharacterized membrane protein	931
2918592388	430	99.52	1	430	1	419	0.0e+00	602.2	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
2918592390	432	96.97	3	432	11	426	0.0e+00	606.2	COG0141	Histidinol dehydrogenase	425
2918592391	157	97.5	1	157	5	160	1.3e-94	309.2	COG5328	Uncharacterized protein, UPF0262 family	160
2918592392	162	97.97	13	148	2	146	1.2e-30	101	COG0394	Protein-tyrosine-phosphatase	139
2918592393	72	96	1	72	1	72	3.3e-34	110.8	COG0361	Translation initiation factor IF-1	75
2918592394	207	98.97	4	202	2	193	2.3e-70	230.3	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
2918592395	74	86.15	11	72	2	57	2.0e-21	70	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
2918592397	343	99.39	1	329	1	327	0.0e+00	434.2	COG1087	UDP-glucose 4-epimerase	329
2918592398	388	92.68	10	387	26	392	4.9e-105	346	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918592399	142	97.71	1	142	3	130	2.3e-53	174.6	COG1970	Large-conductance mechanosensitive channel	130
2918592400	1169	84.77	626	1024	56	389	2.0e-58	193.5	COG0642	Signal transduction histidine kinase	336
2918592400	1169	97.4	1	549	3	489	3.4e-124	409.3	COG0591	Na+/proline symporter	493
2918592401	615	20.94	79	302	78	166	2.3e-104	22.9	COG0840	Methyl-accepting chemotaxis protein	408
2918592401	615	76	295	600	102	424	2.3e-104	321.3	COG0840	Methyl-accepting chemotaxis protein	408
2918592402	247	83.75	175	246	14	80	2.4e-20	65.9	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918592403	243	80	172	243	16	79	3.6e-25	81.3	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918592404	528	93.61	1	526	35	547	0.0e+00	532.6	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
2918592406	181	96.34	1	161	4	161	2.1e-60	197.4	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
2918592407	129	91.73	2	129	5	126	2.8e-27	89.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918592408	351	99.15	4	350	2	350	0.0e+00	441.4	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918592409	302	98.15	26	295	2	266	1.5e-93	307.2	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918592410	753	98.67	1	749	4	747	0.0e+00	743.9	COG0643	Chemotaxis protein histidine kinase CheA	716
2918592411	121	90.98	1	121	6	126	6.6e-31	101.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918592412	99	71.79	1	99	15	98	3.5e-11	37.5	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918592413	531	79.29	87	489	89	425	9.8e-72	236.8	COG0840	Methyl-accepting chemotaxis protein	408
2918592415	972	82.42	807	962	24	159	2.1e-64	69.7	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
2918592415	972	91.09	7	628	2	563	0.0e+00	600	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2918592415	972	99.39	616	786	1	164	2.1e-64	156.2	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
2918592416	111	96.49	1	111	1	110	1.3e-37	122.5	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
2918592417	548	99.41	5	540	3	505	0.0e+00	486.9	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
2918592418	162	98.73	5	162	3	158	6.8e-46	150.6	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
2918592419	93	98.88	4	92	2	89	9.1e-32	103.7	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
2918592420	114	89.38	8	114	2	102	1.5e-33	109.7	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
2918592421	164	69.5	7	157	38	176	1.4e-28	94.6	COG3145	Alkylated DNA repair dioxygenase AlkB	194
2918592423	143	30.38	50	98	38	61	2.4e-01	5.2	COG4238	Outer membrane murein-binding lipoprotein Lpp	78
2918592423	143	40.51	12	52	36	67	2.4e-01	4.6	COG4238	Outer membrane murein-binding lipoprotein Lpp	78
2918592424	738	24.92	635	727	190	271	1.6e-111	23.1	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918592424	738	96.6	1	306	2	257	1.5e-67	221.4	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918592424	738	99.7	325	665	2	329	1.6e-111	354.1	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918592426	402	100	1	402	1	394	5.3e-125	411.9	COG0183	Acetyl-CoA acetyltransferase	392
2918592427	598	98.25	18	462	5	396	9.2e-107	352.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918592428	1249	29.29	433	586	100	169	8.9e-02	7.3	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2918592428	1249	42.26	258	412	48	148	8.9e-02	3.8	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2918592428	1249	64.44	346	521	15	168	8.9e-02	9.1	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2918592428	1249	78.85	894	1206	4	264	1.0e-45	150.1	COG0790	TPR repeat	292
2918592429	308	96.53	8	293	4	253	5.5e-59	193.9	COG0730	Uncharacterized membrane protein YfcA	258
2918592431	145	96.23	1	145	4	156	6.3e-33	109.2	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918592432	251	96.23	32	251	4	233	7.3e-64	209.6	COG1407	Metallophosphoesterase superfamily enzyme	235
2918592433	792	93.99	1	792	40	852	0.0e+00	849	COG1201	Lhr-like helicase	814
2918592434	167	95.33	1	156	1	143	1.6e-41	136.1	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918592435	153	76.88	2	145	41	183	3.0e-38	126	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918592436	213	70.55	9	213	3	208	3.5e-39	129.1	COG1284	Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains	289
2918592437	212	70.21	7	212	4	208	8.2e-43	141	COG1284	Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains	289
2918592438	313	99.65	19	313	1	286	3.5e-128	421.4	COG4976	Predicted methyltransferase, contains TPR repeat	287
2918592440	165	67.91	4	165	68	213	5.0e-38	125.6	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
2918592441	363	99.03	44	356	2	308	2.2e-111	366.1	COG0167	Dihydroorotate dehydrogenase	310
2918592442	117	98.26	3	117	2	114	6.3e-53	172.2	COG3502	Uncharacterized conserved protein, DUF952 family	115
2918592443	216	95.73	4	211	3	204	1.0e-55	182.8	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918592444	216	98.7	1	216	1	228	1.6e-63	209.2	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
2918592445	250	66.04	10	242	52	228	5.3e-24	79.2	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918592446	431	94.87	5	430	13	419	4.1e-76	250.8	COG3307	O-antigen ligase	424
2918592448	426	83.82	10	423	15	418	2.5e-46	152.5	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2918592449	253	85.16	13	253	34	274	3.9e-42	138.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918592450	645	90.69	209	642	19	476	6.9e-69	227	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2918592451	97	31.71	60	94	13	38	1.2e-04	5.3	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
2918592451	97	63.41	4	64	2	53	1.2e-04	16.8	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
2918592452	241	97.14	1	226	5	242	5.7e-67	219.8	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
2918592453	182	79.53	2	181	32	202	3.5e-62	203.9	COG1859	RNA:NAD 2'-phosphotransferase, TPT1/KptA family	211
2918592455	365	82.16	6	164	2	153	1.2e-65	42.3	COG0717	Deoxycytidine triphosphate deaminase	183
2918592455	365	98.92	141	365	2	184	1.2e-65	178.6	COG0717	Deoxycytidine triphosphate deaminase	183
2918592458	394	98.99	1	393	4	396	0.0e+00	459.9	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2918592459	130	98.41	2	127	2	125	7.5e-59	191.6	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
2918592460	329	99.3	13	329	2	286	1.7e-99	327.2	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
2918592461	305	98.39	1	303	5	310	3.6e-126	415.1	COG0078	Ornithine carbamoyltransferase	310
2918592462	399	96.54	1	396	13	403	0.0e+00	525.1	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2918592463	177	98.82	1	177	1	167	3.0e-71	233.5	COG5352	Uncharacterized protein	169
2918592464	227	98.28	3	227	2	229	2.7e-87	286.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918592465	241	94.29	1	238	6	236	3.6e-65	214.1	COG0704	Phosphate uptake regulator	240
2918592466	271	98.03	17	271	6	254	7.7e-127	416.1	COG1117	ABC-type phosphate transport system, ATPase component	253
2918592467	440	16.33	17	113	10	57	6.5e-91	4	COG0581	ABC-type phosphate transport system, permease component	292
2918592467	440	96.26	151	440	12	294	6.5e-91	295.6	COG0581	ABC-type phosphate transport system, permease component	292
2918592468	494	96.5	173	493	11	313	1.0e-102	337.2	COG0573	ABC-type phosphate transport system, permease component	310
2918592469	344	96	1	331	13	324	7.9e-69	226.7	COG0226	ABC-type phosphate transport system, periplasmic component	318
2918592470	423	65.74	55	423	127	385	5.5e-66	218.1	COG0642	Signal transduction histidine kinase	336
2918592471	293	97.41	3	273	7	269	3.0e-115	378.6	COG2326	Polyphosphate kinase 2, PPK2 family	270
2918592473	320	95.65	1	316	8	337	1.4e-84	278.7	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2918592476	52	91.07	1	52	5	55	6.1e-27	87.8	COG0401	Uncharacterized membrane protein YqaE, homolog of Blt101, UPF0057 family	56
2918592479	130	25.33	21	51	9	27	6.0e-04	9.1	COG3798	Uncharacterized protein	75
2918592479	130	26.67	80	120	26	45	6.0e-04	3.7	COG3798	Uncharacterized protein	75
2918592480	293	85.61	172	293	13	125	1.3e-27	90.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918592481	729	96.98	8	729	25	795	2.1e-116	384.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918592482	531	95.96	1	531	18	539	0.0e+00	484.5	COG1178	ABC-type Fe3+ transport system, permease component	540
2918592483	338	99.67	40	337	1	300	7.7e-70	230	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918592484	349	98.58	2	349	4	351	2.7e-106	350.2	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918592485	570	97.18	26	569	5	556	0.0e+00	479.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918592486	541	99.56	35	530	3	453	0.0e+00	623.5	COG0166	Glucose-6-phosphate isomerase	446
2918592487	289	98.07	3	289	6	310	2.6e-43	142.6	COG0078	Ornithine carbamoyltransferase	310
2918592488	226	92.95	1	226	17	227	4.9e-103	338.2	COG4947	Esterase/lipase superfamily enzyme	227
2918592489	321	99.38	12	319	1	319	3.9e-108	355.4	COG3458	Cephalosporin-C deacetylase or related acetyl esterase	321
2918592490	308	95.57	1	307	1	302	2.1e-64	211.8	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918592491	232	96.06	12	217	5	199	4.5e-57	187.3	COG0461	Orotate phosphoribosyltransferase	201
2918592492	345	99.42	1	345	2	343	0.0e+00	523.4	COG0418	Dihydroorotase	344
2918592493	345	99.71	1	341	1	340	0.0e+00	492.6	COG3938	Proline racemase	341
2918592494	440	99.74	13	387	2	378	0.0e+00	530	COG4782	Esterase/lipase superfamily enzyme	377
2918592495	498	99.61	1	496	2	510	0.0e+00	663	COG0427	Acyl-CoA hydrolase	501
2918592496	266	66.08	1	213	1	261	2.2e-32	107.2	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2918592497	430	98.42	1	430	6	441	1.4e-66	220.2	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918592498	273	96.82	1	273	10	283	1.5e-76	252	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918592499	308	94.97	16	307	7	289	3.4e-75	247.4	COG1175	ABC-type sugar transport system, permease component	295
2918592500	381	99.14	3	367	3	349	1.7e-127	419.9	COG3839	ABC-type sugar transport system, ATPase component	338
2918592501	270	71.97	6	209	51	222	7.6e-25	80.8	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918592503	483	92.39	95	479	26	389	4.4e-42	139.7	COG0642	Signal transduction histidine kinase	336
2918592505	682	12	263	333	105	155	8.0e-110	6.1	COG0840	Methyl-accepting chemotaxis protein	408
2918592505	682	22.35	53	266	50	144	8.0e-110	23.5	COG0840	Methyl-accepting chemotaxis protein	408
2918592505	682	75.76	309	617	104	425	8.0e-110	340.4	COG0840	Methyl-accepting chemotaxis protein	408
2918592507	64	45.76	1	61	61	114	1.0e-11	38.2	COG0594	RNase P protein component	117
2918592508	601	93.97	268	596	2	297	5.9e-110	362.2	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
2918592509	217	95.5	12	217	6	196	1.9e-65	214.4	COG0218	GTP-binding protein EngB required for normal cell division	200
2918592510	125	48.33	1	125	1	116	3.6e-20	66.7	COG5343	Anti-sigma-K factor RskA	240
2918592511	294	99.25	24	294	2	264	6.0e-108	354.3	COG0548	Acetylglutamate kinase	265
2918592512	305	86.38	3	304	33	292	7.5e-25	82.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918592513	237	96.54	15	230	4	226	2.4e-38	126.6	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918592514	193	12.27	166	190	98	117	1.2e-10	11.5	COG5126	Ca2+-binding protein, EF-hand superfamily	160
2918592514	193	14.11	38	70	132	154	1.2e-10	8.6	COG5126	Ca2+-binding protein, EF-hand superfamily	160
2918592514	193	34.36	67	169	100	155	1.2e-10	12.7	COG5126	Ca2+-binding protein, EF-hand superfamily	160
2918592515	85	100	1	85	1	85	5.3e-45	146.2	COG5568	Uncharacterized protein	85
2918592516	141	92.47	1	138	12	146	2.2e-35	116	COG0071	Molecular chaperone IbpA, HSP20 family	146
2918592517	314	99.04	3	314	2	311	4.9e-130	427.8	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
2918592518	771	16.24	152	398	78	146	4.2e-105	15.2	COG0840	Methyl-accepting chemotaxis protein	408
2918592518	771	78.82	395	725	90	424	4.2e-105	331.4	COG0840	Methyl-accepting chemotaxis protein	408
2918592519	288	94.63	66	288	2	195	4.0e-74	242.9	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2918592520	284	98.53	6	284	3	270	1.2e-104	344	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
2918592521	398	96.65	1	394	13	416	3.0e-109	360.3	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918592523	266	93.26	1	264	1	249	4.4e-86	282.9	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
2918592524	311	98.38	2	308	2	304	6.8e-111	364.8	COG0223	Methionyl-tRNA formyltransferase	307
2918592525	170	99.41	1	167	1	168	3.6e-66	216.2	COG0242	Peptide deformylase	168
2918592526	397	78.4	38	397	96	447	1.2e-110	364.7	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
2918592527	299	98.42	1	299	1	311	1.1e-70	232.6	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918592528	232	97.8	9	232	3	224	1.8e-68	224.9	COG0220	tRNA G46 methylase TrmB	227
2918592529	420	99.49	1	420	1	387	0.0e+00	561.6	COG0192	S-adenosylmethionine synthetase	388
2918592530	139	88.46	14	137	2	116	5.3e-18	60.3	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918592531	529	99.62	1	529	2	519	0.0e+00	542.3	COG0815	Apolipoprotein N-acyltransferase	518
2918592532	379	65.98	30	351	149	437	8.6e-99	325.4	COG1253	Hemolysin or related protein, contains CBS domains	429
2918592533	168	97.4	4	165	3	152	9.0e-53	172.3	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
2918592534	351	97.35	10	350	5	335	0.0e+00	454.9	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
2918592535	467	99.32	20	467	2	439	0.0e+00	536	COG0621	tRNA A37 methylthiotransferase MiaB	437
2918592536	265	85.82	4	255	2	225	2.3e-40	132.9	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918592537	142	89.66	2	141	6	135	5.7e-47	153.6	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2918592538	164	92.06	5	164	10	183	1.1e-32	107.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918592539	222	99.55	1	212	1	220	7.8e-51	167.6	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
2918592540	187	88.17	106	187	3	84	3.8e-29	94.8	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
2918592541	163	96.23	9	153	4	156	3.1e-12	41.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918592542	354	99.37	1	334	2	316	2.9e-102	336.5	COG0180	Tryptophanyl-tRNA synthetase	314
2918592543	134	84.25	7	134	2	124	3.1e-11	39.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918592544	529	99.03	1	515	5	517	0.0e+00	585.1	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
2918592545	942	98.96	37	915	9	866	0.0e+00	1142.3	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
2918592546	904	99.88	14	899	2	854	0.0e+00	1049.3	COG0249	DNA mismatch repair ATPase MutS	843
2918592547	299	98.98	1	299	3	292	1.1e-114	377	COG3176	Putative hemolysin	292
2918592548	746	58.79	608	743	12	118	8.9e-12	38.8	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918592548	746	76.14	15	460	86	385	6.1e-70	231.1	COG0642	Signal transduction histidine kinase	336
2918592549	162	96.41	1	162	3	163	1.4e-49	162.1	COG0597	Lipoprotein signal peptidase	167
2918592550	286	98.1	19	281	2	259	2.3e-71	234.5	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2918592551	377	82.44	3	375	70	393	2.6e-80	264.4	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
2918592552	113	67.35	1	86	27	92	4.0e-06	20.6	COG5416	Uncharacterized integral membrane protein	98
2918592553	100	94.68	1	94	3	91	3.3e-33	108.3	COG0776	Bacterial nucleoid DNA-binding protein	94
2918592554	322	86.88	4	300	11	288	2.8e-74	244.7	COG0616	Periplasmic serine protease, ClpP class	317
2918592555	221	100	1	216	1	216	4.0e-88	288.9	COG5375	Uncharacterized protein	216
2918592556	187	95.38	18	187	3	167	5.1e-59	193	COG1934	Lipopolysaccharide export system protein LptA	173
2918592557	269	99.18	29	269	3	243	1.3e-117	385.6	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
2918592558	516	99.55	3	507	2	447	0.0e+00	578.2	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
2918592559	181	90	1	103	10	108	4.9e-26	85.4	COG1544	Ribosome-associated translation inhibitor RaiA	110
2918592560	153	98.68	2	151	2	151	1.1e-45	149.4	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
2918592561	211	81.63	2	190	35	194	2.5e-64	211.1	COG0576	Molecular chaperone GrpE (heat shock protein)	193
2918592562	363	98.55	12	363	4	343	1.1e-113	374.6	COG1420	Transcriptional regulator of heat shock response	346
2918592563	238	96.97	1	238	8	231	3.8e-100	328.4	COG0689	Ribonuclease PH	230
2918592564	214	98.46	6	214	2	193	8.3e-70	228.7	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
2918592565	402	90.48	3	402	35	414	5.3e-125	411.7	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
2918592566	486	99.77	7	479	2	433	0.0e+00	489.5	COG0593	Chromosomal replication initiation ATPase DnaA	408
2918592568	88	98.86	1	88	1	87	1.7e-30	99.9	COG0268	Ribosomal protein S20	88
2918592569	257	99.25	1	254	3	265	2.1e-89	293.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918592570	298	100	1	298	1	274	4.5e-101	332.5	COG0266	Formamidopyrimidine-DNA glycosylase	273
2918592571	258	99.58	18	258	1	238	3.6e-93	305.4	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918592572	524	99.22	1	524	2	509	0.0e+00	551.8	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
2918592573	304	98.22	9	296	4	279	1.3e-62	206.4	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
2918592574	124	94.12	2	117	7	118	8.4e-34	110.6	COG2315	Predicted DNA-binding protein with ?double-wing? structural motif, MmcQ/YjbR family	118
2918592575	401	99.5	2	401	2	400	0.0e+00	458	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
2918592576	527	99.62	1	521	2	527	0.0e+00	801.2	COG4108	Peptide chain release factor RF-3	528
2918592577	156	93.96	8	156	9	148	9.6e-62	201.3	COG0756	dUTPase	148
2918592578	205	99.04	1	205	1	206	8.0e-53	173.1	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918592579	322	99.34	12	315	2	301	6.3e-123	404	COG0031	Cysteine synthase	300
2918592580	510	99.19	14	506	2	489	0.0e+00	657.9	COG0606	Predicted ATPase with chaperone activity	490
2918592581	319	99.05	5	317	3	314	1.7e-95	313.9	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2918592582	170	98.28	9	144	2	115	7.8e-46	149.1	COG3450	Predicted enzyme of the cupin superfamily	116
2918592583	366	99.71	1	344	1	349	0.0e+00	457.6	COG3839	ABC-type sugar transport system, ATPase component	338
2918592584	280	94.35	2	280	13	279	5.6e-81	266.3	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918592585	321	96.98	27	319	4	292	2.0e-62	205.4	COG1175	ABC-type sugar transport system, permease component	295
2918592586	432	97.07	1	427	13	442	4.2e-70	231.6	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918592587	186	90	13	186	8	178	1.2e-49	163	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918592588	122	96.49	13	122	3	112	1.8e-35	115.7	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
2918592589	307	98.9	27	302	3	271	4.0e-98	322.1	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
2918592590	372	100	1	372	1	365	3.8e-125	412.3	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
2918592591	197	98.97	5	197	1	192	1.2e-93	306.5	COG3963	Phospholipid N-methyltransferase	194
2918592592	198	89	1	196	8	193	2.9e-24	80.3	COG0406	Broad specificity phosphatase PhoE	208
2918592593	235	94.58	1	230	10	236	1.1e-76	251.6	COG0284	Orotidine-5'-phosphate decarboxylase	240
2918592594	95	100	1	95	1	96	4.0e-42	136.9	COG5470	Uncharacterized conserved protein, DUF1330 family	96
2918592595	326	96.38	8	292	2	267	2.0e-62	205.4	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2918592597	268	98.17	1	267	4	271	1.6e-95	314	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
2918592598	222	92.56	1	214	9	207	6.2e-40	131.7	COG0625	Glutathione S-transferase	211
2918592599	323	86.22	1	292	48	341	3.1e-122	402.3	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
2918592600	290	13.08	1	77	2	43	1.3e-27	6.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918592600	290	59.5	92	285	113	303	1.3e-27	83.9	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918592601	74	29.03	1	74	110	181	4.2e-41	136	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
2918592602	423	97.21	79	423	10	357	6.6e-94	309.6	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
2918592603	425	94.62	1	425	25	446	0.0e+00	791.8	COG3487	Uncharacterized iron-regulated protein	446
2918592604	484	99.58	4	484	3	481	0.0e+00	867.5	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
2918592605	373	99.44	2	373	3	359	0.0e+00	529.3	COG3489	Predicted periplasmic lipoprotein	359
2918592606	364	98.63	4	364	5	365	0.0e+00	571.8	COG3490	Uncharacterized protein	366
2918592607	150	95.03	1	150	5	157	1.4e-50	165.6	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
2918592608	149	94.33	4	145	8	140	8.1e-36	117.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918592609	212	92.41	1	209	17	235	2.0e-30	100.3	COG0775	Nucleoside phosphorylase	234
2918592610	525	98.48	7	201	3	197	9.3e-69	225.3	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2918592610	525	100	202	525	1	316	0.0e+00	490.1	COG0519	GMP synthase, PP-ATPase domain/subunit	315
2918592612	192	79.9	1	192	14	180	9.1e-18	60.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918592613	233	25.4	3	62	39	86	2.0e-32	6.3	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
2918592613	233	97.88	44	233	2	186	2.0e-32	107.2	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
2918592614	201	92.86	1	184	7	175	4.4e-33	108.9	COG1514	2'-5' RNA ligase	180
2918592616	115	98.29	1	115	1	115	3.1e-40	131.5	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2918592617	158	98.06	4	158	2	153	9.5e-54	175.7	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
2918592618	412	99.48	4	412	3	387	0.0e+00	510.1	COG2309	Leucyl aminopeptidase (aminopeptidase T)	385
2918592619	287	96.01	1	287	8	296	5.3e-46	151.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918592620	166	87.22	30	166	14	129	1.0e-27	91.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918592621	235	93.36	3	234	9	233	2.5e-58	191.5	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918592622	400	96.51	1	393	10	369	1.1e-100	331.3	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918592623	532	98.2	11	505	4	440	0.0e+00	546.4	COG1570	Exonuclease VII, large subunit	440
2918592624	80	23.9	1	72	13	77	5.0e-02	7.2	COG3752	Steroid 5-alpha reductase family enzyme	272
2918592626	327	97.72	1	327	3	345	1.0e-77	256.3	COG0673	Predicted dehydrogenase	342
2918592627	186	83.98	1	162	4	176	1.7e-26	83.2	COG1335	Nicotinamidase-related amidase	205
2918592628	327	96	1	327	6	317	8.7e-91	298.7	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918592629	316	96.88	1	316	2	311	8.7e-99	324.9	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918592630	147	80.25	1	147	27	156	1.0e-11	39.9	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918592631	302	96.68	4	300	3	293	1.1e-68	226.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918592632	332	97.81	1	319	1	313	6.4e-109	358	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918592633	807	5.83	1	54	267	304	0.0e+00	1.9	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
2918592633	807	100	143	806	1	652	0.0e+00	728.3	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
2918592634	360	98.81	1	343	4	336	0.0e+00	431.5	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
2918592635	292	60.98	86	240	46	170	1.1e-06	22	COG3642	tRNA A-37 threonylcarbamoyl transferase component Bud32	204
2918592636	134	99.15	1	118	1	117	1.5e-53	174.3	COG0292	Ribosomal protein L20	118
2918592637	67	98.46	1	65	1	64	8.4e-27	87.9	COG0291	Ribosomal protein L35	65
2918592638	140	79.55	1	140	34	173	2.3e-66	217.1	COG0290	Translation initiation factor IF-3	176
2918592639	262	93.22	9	262	8	282	1.4e-22	71.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918592640	204	96.86	2	193	7	191	9.9e-76	248.2	COG3672	Predicted transglutaminase-like cysteine proteinase	191
2918592641	327	33.15	9	83	26	84	1.9e-53	30	COG1633	Rubrerythrin	176
2918592641	327	99.44	81	257	2	178	1.9e-53	144	COG1633	Rubrerythrin	176
2918592642	157	97.74	14	147	3	132	4.3e-44	144.2	COG2346	Truncated hemoglobin YjbI	133
2918592643	367	99.72	1	360	1	362	0.0e+00	591.4	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
2918592644	364	84.09	213	353	16	126	3.1e-27	89	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918592645	357	94.07	2	357	16	364	3.7e-99	326.5	COG4188	Predicted dienelactone hydrolase	365
2918592646	172	72.84	22	155	40	157	1.4e-11	39.4	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918592647	192	83.08	11	146	1	108	8.6e-21	69.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918592648	133	88.24	1	127	6	125	2.2e-10	34.5	COG3631	Ketosteroid isomerase-related protein	133
2918592649	202	85.8	2	173	18	156	5.2e-12	40.6	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918592650	289	96.76	1	288	2	270	5.0e-46	151.2	COG0388	Predicted amidohydrolase	274
2918592651	608	99.34	5	608	4	602	0.0e+00	1020.2	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
2918592652	135	99.26	1	135	1	134	2.4e-83	271.5	COG4954	Uncharacterized protein	135
2918592653	258	78.79	129	256	20	123	2.2e-19	63.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918592654	299	97.72	1	294	3	302	3.0e-55	181.7	COG0492	Thioredoxin reductase	305
2918592655	152	90.67	1	143	1	136	1.4e-32	107.2	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918592657	470	96.49	8	464	6	445	6.0e-126	415	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918592658	291	95.35	1	290	5	291	9.7e-40	131	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918592659	342	91.85	76	342	19	266	5.9e-105	344.4	COG3757	Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family	269
2918592660	62	96.61	1	58	2	58	1.7e-32	105.5	COG3422	Uncharacterized conserved protein YegP, UPF0339 family	59
2918592661	241	97.98	1	200	1	194	3.5e-43	142	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2918592662	149	92.36	14	149	9	141	7.9e-27	88.8	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918592663	101	97.98	1	99	1	97	3.0e-57	185.2	COG3526	Predicted selenoprotein, Rdx family	99
2918592665	136	15.16	7	115	38	111	6.1e-11	35.9	COG4964	Flp pilus assembly protein, secretin CpaC	455
2918592666	61	96.55	1	58	1	56	4.1e-26	85.1	COG3847	Flp pilus assembly protein, pilin Flp	58
2918592667	170	97.62	1	166	4	167	1.4e-53	175.5	COG4960	Flp pilus assembly protein, protease CpaA	168
2918592668	268	97.1	1	268	1	268	4.9e-99	325.4	COG3745	Flp pilus assembly protein CpaB	276
2918592669	527	96.93	26	527	16	488	0.0e+00	564.4	COG4964	Flp pilus assembly protein, secretin CpaC	455
2918592670	230	91.96	11	229	10	215	1.1e-99	326.7	COG5461	Type IV pilus biogenesis protein CpaD/CtpE	224
2918592671	427	16.62	99	166	3	67	3.1e-127	41.1	COG4963	Flp pilus assembly protein, ATPase CpaE	366
2918592671	427	67.01	163	427	129	390	3.1e-127	378.4	COG4963	Flp pilus assembly protein, ATPase CpaE	366
2918592672	490	98.34	88	448	3	358	0.0e+00	542.4	COG4962	Pilus assembly protein, ATPase of CpaF family	355
2918592673	334	99.68	4	334	2	309	1.2e-120	396.5	COG4965	Flp pilus assembly protein TadB	309
2918592674	266	79.44	2	266	63	317	4.6e-67	220.9	COG2064	Pilus assembly protein TadC	320
2918592675	274	99.62	10	268	2	260	1.7e-102	336.9	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918592676	464	94.87	7	463	24	485	0.0e+00	480.1	COG0260	Leucyl aminopeptidase	485
2918592677	434	93.41	11	433	2	384	1.1e-108	357.9	COG1488	Nicotinic acid phosphoribosyltransferase	405
2918592679	283	89.56	14	279	27	249	9.5e-32	105.6	COG0791	Cell wall-associated hydrolase, NlpC family	197
2918592680	114	60.9	9	114	18	98	3.3e-17	57.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918592681	368	98.55	6	360	2	342	0.0e+00	541.8	COG2899	Uncharacterized protein	346
2918592682	308	96.01	8	297	9	297	5.4e-38	125.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918592683	293	98.67	1	290	2	298	1.7e-60	199.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918592684	498	99.37	4	485	2	477	0.0e+00	504.1	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918592685	356	97.53	1	356	10	364	0.0e+00	433.9	COG4269	Uncharacterized membrane protein YjgN, DUF898 family	364
2918592686	356	96.15	76	351	8	307	8.7e-30	98.4	COG0501	Zn-dependent protease with chaperone function	302
2918592687	349	100	45	344	1	301	1.4e-70	232.4	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918592688	156	89.33	1	148	1	134	1.0e-46	153.1	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918592689	348	98.58	1	347	4	350	2.4e-100	330.2	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
2918592690	303	93.33	1	299	21	300	3.3e-108	355.7	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
2918592691	388	94.17	149	387	3	212	2.9e-78	256.9	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
2918592692	312	99.68	1	308	1	313	4.5e-128	421.4	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
2918592693	246	94.17	25	246	8	217	6.5e-69	226	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
2918592694	169	98.14	8	168	1	158	3.7e-65	212.8	COG3265	Gluconate kinase	161
2918592695	433	98.45	32	413	4	385	3.8e-80	264.4	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918592696	453	98.88	4	452	5	445	1.2e-127	420.6	COG0174	Glutamine synthetase	443
2918592697	415	97.94	1	415	3	382	1.6e-71	234	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918592698	546	99.25	4	537	4	533	0.0e+00	892.6	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
2918592699	381	99.41	17	380	2	340	0.0e+00	592.3	COG4239	ABC-type microcin C transport system, permease component YejE	341
2918592700	364	100	1	363	1	364	0.0e+00	645.6	COG4174	ABC-type microcin C transport system, permease component YejB	364
2918592701	614	98.26	5	612	6	569	0.0e+00	495.8	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2918592702	349	97.54	10	306	3	279	1.5e-130	428.6	COG3770	Murein endopeptidase	284
2918592703	127	86.62	1	127	1	123	2.6e-61	200	COG1803	Methylglyoxal synthase	142
2918592704	340	98.44	7	326	5	319	2.6e-127	418.6	COG0837	Glucokinase	320
2918592705	279	99.63	8	275	2	267	8.9e-99	324.6	COG0289	Dihydrodipicolinate reductase	266
2918592706	239	97.91	1	239	6	239	1.3e-62	205.8	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918592707	139	92.72	1	139	12	151	1.5e-62	204.4	COG3624	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG	151
2918592708	202	98.98	3	199	2	195	1.9e-80	263.4	COG3625	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH	196
2918592709	369	98.64	1	369	1	362	0.0e+00	668.4	COG3626	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI	367
2918592711	300	98.63	3	293	3	289	0.0e+00	591.7	COG3627	Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase	291
2918592712	258	100	1	258	1	258	0.0e+00	500.1	COG4107	ABC-type phosphonate transport system, ATPase component	258
2918592713	235	99.57	1	235	1	234	4.3e-123	403.7	COG4778	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL	235
2918592714	205	87.37	4	174	22	187	2.6e-46	152.1	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918592715	286	94.96	1	261	3	247	2.9e-110	361.9	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
2918592716	301	98.34	1	301	1	296	3.9e-85	280.2	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
2918592717	328	95.77	11	317	12	283	1.0e-91	301.4	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
2918592718	449	90.49	140	445	27	283	8.7e-102	334.3	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
2918592719	215	17.58	29	79	39	70	6.9e-04	5.3	COG1514	2'-5' RNA ligase	180
2918592719	215	27.47	124	200	34	83	6.9e-04	6	COG1514	2'-5' RNA ligase	180
2918592720	378	99.73	4	378	2	377	0.0e+00	588.4	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
2918592721	199	94.27	11	199	3	183	7.6e-81	264.5	COG3709	Ribose 1,5-bisphosphokinase PhnN	192
2918592722	346	88.64	215	345	9	125	2.2e-22	73	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918592723	81	92.5	1	77	7	80	1.2e-10	35.3	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918592724	329	96.28	1	329	4	339	9.4e-113	371	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
2918592725	308	97.45	16	308	3	269	1.7e-35	117.6	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2918592726	161	97.12	1	140	3	137	2.3e-45	148.4	COG0848	Biopolymer transport protein ExbD	137
2918592727	367	99.07	137	350	1	214	4.1e-66	217.3	COG0811	Biopolymer transport protein ExbB/TolQ	216
2918592728	245	97.07	5	239	7	238	2.8e-63	207.8	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918592729	261	96.81	1	258	6	248	3.9e-99	325.6	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918592730	257	97.29	3	257	5	255	4.4e-70	230.3	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918592731	313	93.13	1	313	14	325	7.6e-53	174.4	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918592732	236	96.9	10	230	5	223	1.9e-57	188.7	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
2918592734	212	96.65	1	206	5	206	5.5e-70	229.6	COG2860	Uncharacterized membrane protein YeiH	209
2918592735	139	89.66	2	139	7	136	2.8e-34	112.5	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2918592736	171	98.65	13	168	2	147	2.6e-44	145	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2918592737	407	99.28	1	406	2	412	0.0e+00	459.6	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918592738	268	98.07	2	260	2	255	1.0e-118	389.7	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
2918592739	198	98.47	1	194	3	195	1.4e-45	150	COG4961	Flp pilus assembly protein TadG	185
2918592740	196	96.94	8	196	5	194	2.2e-40	133	COG4961	Flp pilus assembly protein TadG	185
2918592741	587	98.49	4	587	10	597	0.0e+00	598.6	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
2918592742	1833	10.22	621	682	357	406	0.0e+00	12.7	COG0069	Glutamate synthase domain 2	485
2918592742	1833	99.46	8	378	2	371	5.7e-90	295.7	COG0067	Glutamate synthase domain 1	371
2918592742	1833	99.8	693	1322	2	489	0.0e+00	715.7	COG0069	Glutamate synthase domain 2	485
2918592742	1833	100	1338	1761	1	304	0.0e+00	443.2	COG0070	Glutamate synthase domain 3	301
2918592743	442	47.78	247	441	8	190	4.4e-25	18.2	COG0477	MFS family permease	338
2918592743	442	65.54	29	304	2	252	4.4e-25	67.3	COG0477	MFS family permease	338
2918592744	359	98.82	8	272	3	253	6.4e-80	262.2	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2918592745	667	99.82	48	617	2	569	0.0e+00	778.5	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2918592746	207	88.26	4	207	25	212	1.1e-71	234.9	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918592747	131	92.86	1	122	8	111	7.7e-47	152.2	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
2918592748	253	96.06	3	253	6	249	8.5e-90	294.8	COG3346	Cytochrome oxidase assembly protein ShyY1	252
2918592749	406	98.99	1	406	1	393	0.0e+00	553.9	COG1015	Phosphopentomutase	397
2918592750	325	95.66	1	324	8	338	1.2e-101	334.6	COG1816	Adenosine deaminase	345
2918592751	209	99.05	1	209	3	210	9.9e-91	297.5	COG0035	Uracil phosphoribosyltransferase	210
2918592752	173	79.53	1	173	44	214	7.9e-62	203.2	COG3577	Predicted aspartyl protease	215
2918592753	436	98.85	1	436	4	434	0.0e+00	585.4	COG0213	Thymidine phosphorylase	435
2918592754	257	94.3	6	252	8	222	8.2e-75	245.4	COG0274	Deoxyribose-phosphate aldolase	228
2918592755	266	96.96	1	265	7	261	6.8e-85	279.3	COG0005	Purine nucleoside phosphorylase	262
2918592756	134	92.7	1	133	7	133	1.1e-48	159	COG0295	Cytidine deaminase	134
2918592757	323	99.67	1	323	1	303	3.0e-111	365.6	COG1079	ABC-type uncharacterized transport system, permease component	304
2918592758	367	95.53	1	367	9	350	4.9e-109	358.7	COG4603	ABC-type uncharacterized transport system, permease component	356
2918592759	503	99.8	3	500	2	501	0.0e+00	677	COG3845	ABC-type uncharacterized transport system, ATPase component	501
2918592760	330	94.33	1	329	16	348	8.1e-104	341.6	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
2918592761	220	94.83	47	220	4	168	4.4e-70	229.6	COG0225	Peptide methionine sulfoxide reductase MsrA	174
2918592764	633	99.17	1	602	5	605	0.0e+00	892.1	COG0443	Molecular chaperone DnaK (HSP70)	579
2918592765	378	99.74	1	378	1	384	0.0e+00	528.5	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2918592766	183	99.45	1	181	2	182	8.9e-82	267.8	COG3803	Uncharacterized conserved protein, DUF924 family	182
2918592767	70	97.22	1	70	3	72	1.4e-27	90.4	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
2918592768	501	99.4	1	501	1	501	0.0e+00	717.8	COG3333	TctA family transporter	504
2918592770	327	99.37	4	326	2	318	1.5e-114	376.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918592771	448	98.72	1	448	3	463	0.0e+00	536.2	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918592772	600	97.35	1	592	16	603	0.0e+00	781	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2918592773	61	100	1	57	1	57	1.3e-26	87.1	COG0333	Ribosomal protein L32	57
2918592774	1002	94.5	1	308	6	314	1.4e-88	291.3	COG0258	5'-3' exonuclease	310
2918592774	1002	99.66	379	1002	3	597	0.0e+00	815.2	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
2918592777	144	93.98	11	142	5	129	1.3e-26	87.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918592778	463	98.33	5	463	7	417	7.3e-97	319.4	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918592780	69	98.51	1	69	1	66	1.8e-32	105.6	COG1278	Cold shock protein, CspA family	67
2918592783	152	98.71	1	152	1	153	4.7e-48	157.2	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
2918592784	764	90.04	49	742	8	649	0.0e+00	744.4	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2918592785	192	78.67	1	191	44	220	1.3e-71	234.8	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2918592786	191	97.79	36	178	3	135	1.5e-51	168.3	COG3474	Cytochrome c2	135
2918592787	251	97.98	6	251	3	244	3.5e-101	331.8	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
2918592788	287	98.21	4	282	2	276	2.3e-94	310.1	COG0077	Prephenate dehydratase	279
2918592789	317	100	24	314	1	284	3.7e-98	323	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
2918592790	138	86.52	6	138	17	138	5.9e-26	85.5	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2918592792	625	72.65	16	505	3	427	0.0e+00	506.6	COG2812	DNA polymerase III, gamma/tau subunits	515
2918592793	107	97.14	1	104	4	105	4.6e-38	124	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
2918592794	211	97.2	8	211	1	208	7.4e-64	209.7	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
2918592795	201	98.48	4	201	4	198	1.0e-77	254.3	COG0353	Recombinational DNA repair protein RecR	198
2918592796	421	97.69	1	354	7	345	2.0e-130	429.3	COG2951	Membrane-bound lytic murein transglycosylase B	343
2918592797	153	92.06	1	152	10	183	1.4e-08	28.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918592798	529	51.96	205	437	8	206	2.7e-21	19.2	COG0477	MFS family permease	338
2918592798	529	53.52	1	211	8	212	2.7e-21	57.6	COG0477	MFS family permease	338
2918592799	198	98.7	11	169	2	153	4.5e-52	170.3	COG0779	Ribosome maturation factor RimP	153
2918592800	538	48.87	402	512	38	102	2.1e-02	10.9	COG3743	 Predicted 5' DNA nuclease, flap endonuclease-1-like, helix-3-turn-helix (H3TH) domain	133
2918592800	538	97.49	161	374	3	196	2.9e-88	288.2	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
2918592801	233	94.74	20	115	5	94	6.7e-30	97.1	COG2740	Predicted RNA-binding protein YlxR, DUF448 family	95
2918592802	915	99.29	411	915	3	559	0.0e+00	548	COG0532	Translation initiation factor IF-2, a GTPase	509
2918592803	138	96.64	1	126	4	118	4.9e-36	117.7	COG0858	Ribosome-binding factor A	118
2918592804	315	98.71	6	315	3	308	2.6e-107	353.2	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
2918592805	89	100	1	89	1	89	2.7e-37	121.1	COG0184	Ribosomal protein S15P/S13E	89
2918592806	715	99.86	1	695	1	693	0.0e+00	1088.3	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
2918592807	338	98.01	34	338	6	301	4.2e-93	306.1	COG2813	16S rRNA G1207 methylase RsmC	300
2918592808	314	98.4	1	314	2	309	2.5e-71	234.7	COG0679	Predicted permease	311
2918592809	330	96.84	5	327	1	306	4.4e-76	250.2	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918592810	179	99.42	7	179	2	171	1.9e-84	275.8	COG3807	SH3-like domain	171
2918592811	334	99.08	5	331	2	325	2.3e-114	375.9	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918592813	158	62.35	4	147	52	152	7.7e-10	33.9	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918592814	255	94.64	2	252	3	249	5.3e-82	269.2	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
2918592815	375	99.45	5	375	2	362	3.4e-116	382.6	COG1195	Recombinational DNA repair ATPase RecF	363
2918592816	367	96.83	12	367	2	367	1.1e-116	384.4	COG4782	Esterase/lipase superfamily enzyme	377
2918592817	324	92.69	4	322	23	339	4.6e-98	322.7	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
2918592818	728	99.48	28	727	4	762	0.0e+00	715.8	COG0209	Ribonucleotide reductase alpha subunit	696
2918592819	132	92.31	1	132	3	134	2.7e-54	177.3	COG1780	Protein involved in ribonucleotide reduction	141
2918592820	73	88.75	1	72	1	71	1.1e-17	58.4	COG0695	Glutaredoxin	80
2918592822	209	70.92	2	209	74	273	8.3e-65	213	COG1072	Panthothenate kinase	283
2918592823	260	48.7	1	259	4	247	1.1e-87	289.1	COG1129	ABC-type sugar transport system, ATPase component	500
2918592824	360	96.24	37	360	8	314	7.5e-91	298.8	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918592825	340	93.27	1	332	14	318	4.2e-73	240.4	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918592826	410	96.77	93	399	2	301	2.6e-43	142.7	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918592827	602	98.5	2	601	8	600	0.0e+00	746	COG0514	Superfamily II DNA helicase RecQ	590
2918592828	69	18.53	1	69	1	73	1.5e-34	113.8	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2918592829	210	81.25	1	210	10	217	9.0e-53	173.7	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918592831	122	95.58	7	120	5	112	3.2e-38	124.2	COG3895	Membrane-bound inhibitor of C-type lysozyme	112
2918592835	64	44.83	1	59	5	56	8.3e-05	17.4	COG1460	DNA-directed RNA polymerase, subunit F	114
2918592836	616	98.82	24	610	7	591	0.0e+00	472.2	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918592837	341	98.6	45	337	3	284	1.2e-84	278.3	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2918592838	262	95.59	1	261	12	271	2.1e-101	333.1	COG3752	Steroid 5-alpha reductase family enzyme	272
2918592839	457	98.21	5	456	3	441	0.0e+00	699.9	COG2907	Predicted NAD/FAD-binding protein	447
2918592840	272	98.47	1	268	1	257	3.7e-122	400.7	COG3496	Uncharacterized conserved protein, DUF1365 family	261
2918592841	410	97.55	124	409	6	284	7.6e-105	344.4	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2918592842	125	76.97	1	125	38	164	2.0e-40	132.9	COG4731	Uncharacterized conserved protein, DUF2147 family	162
2918592843	143	98.51	2	136	2	133	4.6e-62	202.6	COG4852	Uncharacterized membrane protein	134
2918592844	180	92.47	7	180	8	179	4.9e-39	128.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918592845	227	95.42	1	227	11	239	3.0e-101	332.2	COG5343	Anti-sigma-K factor RskA	240
2918592846	345	93.98	1	127	6	130	1.4e-21	70.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918592846	345	96.93	124	345	3	223	1.1e-54	179.3	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918592847	145	87.97	5	137	7	123	3.3e-21	69.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918592848	484	61.4	297	477	82	221	1.9e-05	16.5	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918592848	484	93.24	1	194	14	206	2.8e-62	204.4	COG5278	Extracellular (periplasmic) sensor domain CHASE3 (specificity unknown)	207
2918592849	141	24.84	22	141	5	120	5.7e-10	33	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918592850	330	95.49	1	129	4	130	3.2e-17	56.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918592850	330	96.49	118	330	3	222	5.7e-50	163.9	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918592851	151	90.23	1	141	6	125	1.7e-26	87.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918592852	736	98.8	1	736	9	749	0.0e+00	1010.5	COG4251	Bacteriophytochrome (light-regulated signal transduction histidine kinase)	750
2918592858	269	99.21	1	265	2	252	3.0e-76	250.9	COG3926	Lysozyme family protein	252
2918592868	716	11.78	540	715	735	840	2.4e-11	37.1	COG5281	Phage-related minor tail protein	833
2918592868	716	35.44	13	344	29	347	2.4e-11	10.5	COG5281	Phage-related minor tail protein	833
2918592869	86	15.87	2	69	23	55	2.9e-05	18.5	COG2976	Putative negative regulator of RcsB-dependent stress response	207
2918592888	530	69.51	6	323	21	232	2.7e-34	112.4	COG5410	Uncharacterized protein	305
2918592888	530	74.26	354	523	43	192	6.5e-46	150.3	COG5362	Phage terminase large subunit	202
2918592899	110	36.13	12	91	15	57	1.7e-04	16.3	COG2522	Predicted transcriptional regulator	119
2918592901	186	86.23	2	177	12	155	1.8e-11	37.7	COG4333	Uncharacterized protein	167
2918592906	482	94.95	9	475	3	416	6.8e-51	167.6	COG0305	Replicative DNA helicase	435
2918592908	199	13.66	130	174	127	148	5.1e-05	2.9	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
2918592908	199	62.73	4	117	7	107	5.1e-05	13.1	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
2918592910	182	76.36	98	150	8	49	2.1e-03	11	COG3130	Ribosome modulation factor	55
2918592911	116	36.19	32	109	14	51	1.0e-03	12.3	COG1447	Phosphotransferase system cellobiose-specific component IIA	105
2918592919	72	54.17	3	69	13	64	6.3e-09	30.3	COG4197	DNA-binding transcriptional regulator YdaS, prophage-encoded, Cro superfamily	96
2918592920	153	63.85	19	140	3	85	8.8e-11	37.3	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918592922	98	9.45	13	91	264	308	8.0e-05	15	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
2918592924	103	43.94	2	95	20	77	8.6e-04	13.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918592937	131	43.87	2	105	72	139	7.7e-08	26.7	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2918592948	295	92.02	33	292	17	258	7.9e-64	209.8	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2918592949	130	80.89	1	130	5	131	2.4e-48	158.2	COG1607	Acyl-CoA hydrolase	157
2918592951	454	98.65	18	454	4	440	0.0e+00	505.7	COG3182	Uncharacterized iron-regulated membrane protein	442
2918592952	158	99.22	33	158	2	129	5.1e-57	186.2	COG4922	Predicted SnoaL-like aldol condensation-catalyzing enzyme	129
2918592953	203	100	2	203	1	211	7.2e-88	288.3	COG2910	Putative NADH-flavin reductase	211
2918592954	127	91.67	1	125	9	118	4.7e-43	140.2	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2918592955	153	81.48	1	144	12	165	1.6e-11	38.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918592956	117	97.41	2	117	4	116	3.0e-53	173.5	COG3169	Uncharacterized conserved protein, DUF486 family	116
2918592957	988	98.79	168	836	5	659	0.0e+00	1086	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
2918592959	322	93.83	3	317	19	322	2.4e-54	179.2	COG0627	S-formylglutathione hydrolase FrmB	316
2918592960	141	93.94	2	133	7	130	3.2e-58	189.7	COG5649	Uncharacterized protein	132
2918592961	151	37.5	56	121	5	37	2.2e-04	15.4	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2918592962	202	99.5	3	202	2	201	2.2e-95	312.3	COG5664	Predicted secreted Zn-dependent protease	201
2918592963	200	31.18	1	176	6	87	2.5e-21	70.9	COG2214	Curved DNA-binding protein CbpA, contains a DnaJ-like domain	237
2918592968	579	95.63	391	570	6	180	8.0e-52	169.3	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918592969	369	5.84	342	369	241	255	1.2e-13	5.7	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918592969	369	77.82	53	328	29	228	1.2e-13	37.5	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918592970	341	90.93	2	338	8	328	2.8e-104	343.5	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918592971	564	97.24	8	559	12	540	0.0e+00	443.9	COG1178	ABC-type Fe3+ transport system, permease component	540
2918592972	327	97.01	40	326	2	293	1.8e-71	235.4	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918592973	414	91.23	1	406	38	453	2.6e-124	410	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918592974	150	99.31	1	149	1	143	1.2e-64	211.4	COG4154	L-fucose mutarotase/ribose pyranase, RbsD/FucU family	144
2918592975	343	5.45	310	340	241	254	4.0e-05	5.5	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918592975	343	13.62	44	236	154	188	4.0e-05	9.2	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918592976	339	99.11	1	337	3	337	0.0e+00	526.2	COG0059	Ketol-acid reductoisomerase	338
2918592977	217	91.87	3	206	13	204	6.3e-17	57.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918592978	301	76.52	177	299	21	121	9.0e-26	84.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918592979	348	98.83	1	345	4	340	1.9e-119	393.1	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2918592980	421	99.76	1	408	1	409	0.0e+00	472.8	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2918592981	251	98.77	3	251	2	241	3.5e-91	299.3	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
2918592982	226	90.15	33	178	2	120	4.1e-23	76.4	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918592983	375	53.73	1	374	63	458	9.0e-50	163.3	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
2918592984	160	96.18	2	156	7	157	1.9e-33	110.2	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2918592985	119	91.53	1	107	8	115	4.7e-18	60.2	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918592986	124	88.41	1	124	17	138	4.8e-65	212.2	COG4315	Predicted lipoprotein with conserved Yx(FWY)xxD motif (function unknown)	138
2918592987	185	90.32	8	180	13	180	3.8e-46	151.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918592988	262	98.83	1	260	4	257	1.3e-85	281.9	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2918592989	197	97.6	1	197	1	203	8.4e-44	143.7	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918592990	281	93.62	5	280	6	269	7.6e-87	285.1	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2918592991	176	96.18	10	176	4	154	2.3e-27	90.4	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2918592992	122	87.29	1	102	13	115	3.1e-17	57.6	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918592993	190	98.77	20	190	3	162	8.6e-66	215.2	COG0440	Acetolactate synthase, small subunit	163
2918592994	597	99.64	12	578	2	554	0.0e+00	731.6	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918592997	658	17.13	415	579	431	522	3.1e-74	66.9	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
2918592997	658	71.69	39	420	4	388	3.1e-74	180.2	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
2918592998	297	93.18	6	297	4	290	2.8e-103	339.7	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
2918592999	296	99.53	76	287	2	212	1.5e-71	234.6	COG0560	Phosphoserine phosphatase	212
2918593000	187	95.19	2	187	8	185	2.4e-39	129.8	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918593001	249	98.88	2	246	3	267	5.8e-64	210.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918593002	514	18.36	403	496	266	332	3.3e-125	27.6	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918593002	514	96.99	4	377	9	362	3.3e-125	389	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918593003	307	97.67	1	292	4	297	2.0e-68	225.3	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918593004	372	96.35	64	366	7	296	1.8e-76	251.7	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918593005	175	98.82	5	171	2	169	4.7e-50	164.2	COG0262	Dihydrofolate reductase	167
2918593006	264	99.27	1	264	3	273	1.1e-128	422.7	COG0207	Thymidylate synthase	268
2918593009	170	100	1	169	1	157	3.4e-78	255.5	COG3814	Uncharacterized protein	157
2918593010	67	12.62	1	59	195	232	2.7e-02	8.5	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918593011	69	66.67	1	69	15	82	6.4e-32	103.9	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918593012	1237	13.15	405	664	410	498	1.0e-19	6.4	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2918593012	1237	28.66	1	245	6	199	1.0e-19	47	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2918593012	1237	31.02	719	985	316	525	1.0e-19	14.5	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2918593013	470	98.08	3	470	9	468	2.7e-126	416.6	COG0277	FAD/FMN-containing dehydrogenase	459
2918593014	1048	99.8	13	1014	2	1013	0.0e+00	1037.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2918593015	382	93.59	6	374	16	380	4.5e-39	127.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918593016	102	50.54	1	94	92	185	2.1e-18	61.6	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918593017	824	99.25	54	700	1	666	0.0e+00	841.6	COG0210	Superfamily I DNA or RNA helicase	655
2918593018	274	97.35	14	263	4	260	3.1e-47	155.8	COG3306	Glycosyltransferase involved in LPS biosynthesis, GR25 family	255
2918593019	39	29.03	1	34	45	71	4.5e-04	14.6	COG1314	Preprotein translocase subunit SecG	86
2918593020	160	96.69	8	160	3	148	9.8e-41	133.7	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
2918593021	141	96.69	1	141	3	148	5.6e-36	118.2	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
2918593023	208	88.83	1	207	5	187	1.4e-51	169.6	COG1335	Nicotinamidase-related amidase	205
2918593024	78	92.68	1	78	5	80	1.2e-34	112.8	COG5460	Uncharacterized conserved protein, DUF2164 family	82
2918593025	239	93.72	1	232	11	234	1.6e-72	238.4	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
2918593026	104	99	3	103	1	99	2.5e-42	137.8	COG4541	Uncharacterized membrane protein	100
2918593027	613	12.56	15	148	35	83	1.9e-92	7.9	COG0006	Xaa-Pro aminopeptidase	384
2918593027	613	94.1	153	567	23	389	1.9e-92	295.3	COG0006	Xaa-Pro aminopeptidase	384
2918593029	292	98.03	2	292	6	303	1.9e-78	258.5	COG2264	Ribosomal protein L11 methylase PrmA	300
2918593030	202	94.29	1	200	11	208	3.7e-65	213.9	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
2918593032	155	89.7	1	155	12	159	2.1e-50	165.1	COG0835	Chemotaxis signal transduction protein	165
2918593033	163	98.18	1	163	3	164	2.6e-70	229.7	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
2918593034	202	66.54	1	195	19	187	7.3e-42	138.6	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2918593035	300	98.34	6	298	2	297	3.7e-67	221.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918593036	309	95.35	4	298	7	293	3.5e-48	158.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918593037	177	86.63	8	177	19	180	6.7e-25	82.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918593038	297	94.5	1	296	3	311	9.7e-75	246.1	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2918593039	724	99.55	10	723	3	673	0.0e+00	880.7	COG0272	NAD-dependent DNA ligase	667
2918593040	557	99.64	1	557	1	556	0.0e+00	665.4	COG0497	DNA repair ATPase RecN	557
2918593041	288	98.43	16	270	4	253	2.9e-94	309.6	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
2918593042	319	96.01	6	311	3	291	6.4e-121	397.6	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
2918593043	583	91.09	3	381	5	321	0.0e+00	467.1	COG0206	Cell division GTPase FtsZ	338
2918593044	443	99.31	18	443	4	434	0.0e+00	450.3	COG0849	Cell division ATPase FtsA	418
2918593045	310	98.89	28	297	2	269	7.2e-72	236.3	COG1589	Cell division septal protein FtsQ	269
2918593046	313	99.06	7	310	3	317	6.3e-106	348.5	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
2918593047	434	45.43	252	431	17	190	3.5e-39	25.5	COG0477	MFS family permease	338
2918593047	434	63.71	21	290	5	248	3.5e-39	104.4	COG0477	MFS family permease	338
2918593048	267	94.54	86	257	10	182	1.0e-43	143.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918593049	321	98.3	22	311	3	291	6.4e-96	315.1	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
2918593050	471	99.57	1	465	2	460	0.0e+00	610.5	COG0773	UDP-N-acetylmuramate-alanine ligase	459
2918593051	378	99.16	4	363	2	356	3.1e-114	376.3	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
2918593052	384	97.91	6	373	6	379	4.8e-112	368.8	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
2918593053	469	99.11	3	458	3	448	0.0e+00	481.2	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
2918593054	366	98.77	19	366	2	323	3.8e-105	346.1	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2918593055	468	98.02	1	457	9	453	0.0e+00	486	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
2918593056	489	96.69	3	484	15	482	0.0e+00	529	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
2918593057	580	98.73	30	570	8	631	8.2e-111	365.1	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2918593058	186	99.28	1	138	1	137	1.4e-60	197.6	COG5462	Predicted secreted (periplasmic) protein	138
2918593059	341	97.78	14	318	5	312	2.8e-115	379.6	COG0275	16S rRNA C1402 N4-methylase RsmH	314
2918593060	146	89.73	3	144	2	132	1.4e-35	116.6	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
2918593062	396	97.16	1	396	1	377	2.6e-45	149.8	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918593063	395	96.39	1	394	4	377	6.5e-42	138.6	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918593064	179	43.89	3	177	131	263	5.4e-42	139.1	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2918593065	259	90.04	3	252	26	260	1.9e-91	300.4	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
2918593066	246	99.43	66	240	1	173	2.4e-49	162.1	COG1076	DnaJ-domain-containing proteins 1	174
2918593067	403	98.6	2	384	2	353	2.7e-77	254.5	COG0205	6-phosphofructokinase	347
2918593068	211	99.04	1	209	1	206	1.0e-29	97.7	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918593069	357	84.16	48	357	8	262	2.5e-31	98.8	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2918593070	416	99.76	1	415	1	413	0.0e+00	763.5	COG5379	S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase	414
2918593071	239	70.71	10	199	14	182	3.9e-21	69.5	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918593072	259	95.56	1	259	9	266	3.6e-100	329	COG3757	Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family	269
2918593073	408	97.98	2	343	4	343	3.6e-108	356.2	COG2951	Membrane-bound lytic murein transglycosylase B	343
2918593075	297	97.27	1	291	7	291	4.8e-98	322.4	COG0685	5,10-methylenetetrahydrofolate reductase	291
2918593076	329	67.78	99	282	10	171	2.0e-27	90	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918593077	549	99.07	4	531	3	532	0.0e+00	603.5	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918593078	316	97.73	4	315	3	303	2.4e-78	257.7	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918593079	400	96.51	1	399	2	388	0.0e+00	520.3	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918593080	555	98.92	7	555	2	550	0.0e+00	580.5	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918593081	250	93.93	22	250	2	233	3.2e-69	227.5	COG0748	Putative heme iron utilization protein	245
2918593082	113	91.91	1	113	9	133	1.4e-26	87.5	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918593083	112	86.15	1	112	1	112	1.5e-48	158.8	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
2918593085	463	96.28	239	463	6	238	7.9e-47	155.1	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2918593086	401	95.95	10	401	10	388	2.5e-34	112.9	COG2814	Predicted arabinose efflux permease, MFS family	394
2918593087	215	73.21	20	210	18	170	1.3e-18	63	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918593088	180	80.28	3	180	28	202	8.7e-25	82	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918593089	172	73.75	7	169	24	141	7.6e-10	33.1	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
2918593090	238	97.73	1	222	2	259	3.2e-37	117.6	COG1192	Cellulose biosynthesis protein BcsQ	259
2918593092	381	99.74	4	381	2	379	0.0e+00	440.5	COG1454	Alcohol dehydrogenase, class IV	377
2918593093	462	96.03	1	462	17	476	0.0e+00	431	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918593094	455	99.1	4	454	4	445	0.0e+00	453	COG0174	Glutamine synthetase	443
2918593095	504	94.92	14	500	4	470	4.4e-62	204.6	COG0531	Amino acid transporter	466
2918593096	257	95.82	4	257	2	253	4.3e-109	358.7	COG3931	Predicted N-formylglutamate amidohydrolase	263
2918593097	292	98.94	4	285	3	281	1.8e-73	241.6	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918593098	368	100	56	366	1	301	1.9e-65	215.7	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918593099	294	99.65	13	294	2	282	0.0e+00	460.2	COG4132	ABC-type uncharacterized transport system, permease component	282
2918593100	260	94.76	1	260	9	261	1.1e-54	180	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918593101	352	98.87	1	352	4	352	0.0e+00	441.5	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918593102	348	98.83	1	348	3	339	1.4e-104	344.2	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2918593104	258	99.57	1	258	1	232	1.4e-95	313.7	COG3910	Predicted ATPase	233
2918593105	443	48.56	242	437	5	190	2.0e-33	13.2	COG0477	MFS family permease	338
2918593105	443	69.71	18	270	5	271	2.0e-33	101	COG0477	MFS family permease	338
2918593106	1257	98.08	16	340	6	311	0.0e+00	436	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
2918593106	1257	100	341	1212	1	857	0.0e+00	1371.8	COG1410	Methionine synthase I, cobalamin-binding domain	842
2918593107	415	96.65	9	404	7	381	5.0e-128	421.6	COG2942	Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family	388
2918593108	186	75.6	4	186	13	201	3.6e-41	135.8	COG2365	Protein tyrosine/serine phosphatase	249
2918593110	210	99.15	1	210	3	236	4.8e-39	129.2	COG3637	Opacity protein and related surface antigens	199
2918593114	247	99.59	1	247	1	243	1.9e-91	300.6	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
2918593116	140	96.35	1	140	5	136	1.0e-45	149.5	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
2918593117	850	87.22	727	847	4	119	2.6e-11	36.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918593117	850	99.2	1	735	6	749	0.0e+00	919	COG4251	Bacteriophytochrome (light-regulated signal transduction histidine kinase)	750
2918593119	684	28.15	53	179	5	100	0.0e+00	10.1	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918593119	684	98.83	327	683	5	341	0.0e+00	435.2	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918593120	661	98.99	2	640	1	590	0.0e+00	602.3	COG0358	DNA primase (bacterial type)	568
2918593121	97	95.7	4	91	2	90	2.3e-26	86.3	COG2929	Uncharacterized conserved protein, DUF497 family	93
2918593122	110	53.68	4	106	44	94	6.4e-21	69.1	COG3514	Uncharacterized conserved protein, DUF4415 family	93
2918593123	150	98.65	1	150	3	148	8.6e-58	189.4	COG1610	Uncharacterized conserved protein YqeY	148
2918593124	401	98.92	11	395	3	369	0.0e+00	485.6	COG0505	Carbamoylphosphate synthase small subunit	368
2918593125	465	96.09	8	465	14	455	5.8e-110	362.3	COG0534	Na+-driven multidrug efflux pump	455
2918593126	696	17.18	241	377	71	143	2.5e-111	29.6	COG0840	Methyl-accepting chemotaxis protein	408
2918593126	696	77.88	371	682	95	425	2.5e-111	338.1	COG0840	Methyl-accepting chemotaxis protein	408
2918593128	310	98.99	1	310	1	293	0.0e+00	440.6	COG2321	Predicted metalloprotease	295
2918593129	162	100	1	131	1	131	9.3e-66	214.5	COG5395	Uncharacterized membrane protein	131
2918593130	273	98.79	13	268	1	245	6.4e-35	115.5	COG3279	DNA-binding response regulator, LytR/AlgR family	244
2918593131	1162	43.66	625	806	1	179	0.0e+00	136.5	COG0458	Carbamoylphosphate synthase large subunit	400
2918593131	1162	47.8	823	1043	190	385	0.0e+00	87.7	COG0458	Carbamoylphosphate synthase large subunit	400
2918593131	1162	100	13	484	1	410	0.0e+00	733	COG0458	Carbamoylphosphate synthase large subunit	400
2918593132	61	82.54	2	60	3	54	2.0e-23	76.4	COG4877	Uncharacterized protein	63
2918593133	367	93.99	190	364	10	181	1.2e-48	159.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918593134	482	96.04	283	481	7	200	1.5e-57	188.4	COG1573	Uracil-DNA glycosylase	202
2918593135	414	99.75	7	414	2	404	0.0e+00	685.6	COG4277	Predicted DNA-binding protein with the Helix-hairpin-helix motif	404
2918593136	158	98.68	7	158	1	150	1.6e-62	204.5	COG0782	Transcription elongation factor, GreA/GreB family	151
2918593137	351	73.35	11	351	108	407	1.4e-37	124.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918593138	155	94.3	1	154	3	151	9.2e-44	143.7	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918593139	324	99.02	3	318	2	305	3.0e-128	421.6	COG0492	Thioredoxin reductase	305
2918593140	300	98.34	5	299	1	296	9.8e-71	233.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918593143	104	71.19	4	104	16	99	2.8e-16	54.5	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918593144	370	98.07	1	370	3	358	2.1e-115	380.4	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918593146	345	96.57	16	328	5	314	1.3e-34	114.5	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918593147	314	96.68	7	304	6	296	5.7e-54	178.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918593149	368	98.65	1	368	4	368	1.1e-107	354.6	COG0387	Ca2+/H+ antiporter	368
2918593150	400	98.99	6	400	4	395	0.0e+00	440.5	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918593151	308	91.05	11	276	10	243	7.5e-46	150.5	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918593153	300	95.02	1	293	10	295	4.6e-42	138.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918593154	71	97.01	2	70	2	66	4.7e-32	104.4	COG1278	Cold shock protein, CspA family	67
2918593155	214	93.08	1	214	14	255	5.8e-55	181.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918593156	199	90.57	1	152	10	153	3.9e-53	173.8	COG4991	Uncharacterized conserved protein YraI	155
2918593157	175	84.21	37	168	16	127	3.4e-21	70	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918593158	237	98.28	16	237	2	229	7.8e-70	229.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918593159	459	84.26	118	459	56	387	4.6e-47	156.2	COG0642	Signal transduction histidine kinase	336
2918593160	113	66.2	1	111	9	102	6.8e-21	69	COG0073	tRNA-binding EMAP/Myf domain	123
2918593161	272	97.76	7	272	4	265	1.7e-85	281.2	COG0345	Pyrroline-5-carboxylate reductase	266
2918593162	166	100	1	166	1	166	3.9e-86	281.5	COG5465	Uncharacterized protein	166
2918593163	87	82.52	1	87	8	92	3.5e-35	114.9	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
2918593164	280	95.83	6	280	3	278	5.1e-94	308.9	COG0682	Prolipoprotein diacylglyceryltransferase	287
2918593165	366	99.19	2	366	3	369	0.0e+00	433.1	COG1565	SAM-dependent methyltransferase, MidA family	370
2918593166	264	95.22	10	263	11	249	1.7e-86	284	COG1496	Copper oxidase (laccase) domain	249
2918593167	383	97.44	1	382	2	381	1.6e-78	259	COG0006	Xaa-Pro aminopeptidase	384
2918593169	310	98.43	1	310	6	318	1.0e-127	420.2	COG0462	Phosphoribosylpyrophosphate synthetase	314
2918593170	282	91.81	1	264	6	218	5.1e-16	53.9	COG0671	Membrane-associated phospholipid phosphatase	232
2918593171	502	75.32	21	493	45	456	1.6e-45	150.4	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
2918593172	103	89.38	1	103	8	108	4.3e-48	156.4	COG3952	Uncharacterized N-terminal domain of lipid-A-disaccharide synthase	113
2918593173	250	63.23	3	244	3	229	9.1e-28	92.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918593174	741	22.35	243	440	78	172	6.3e-93	20.2	COG0840	Methyl-accepting chemotaxis protein	408
2918593174	741	77.65	415	729	95	424	6.3e-93	298.2	COG0840	Methyl-accepting chemotaxis protein	408
2918593175	505	99.58	18	500	2	478	0.0e+00	588	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918593176	337	7.35	288	337	566	610	5.8e-102	40.5	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
2918593176	337	46.57	18	301	5	289	5.8e-102	300.3	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
2918593177	696	68.63	130	690	185	639	9.5e-117	385	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918593178	202	98.92	5	98	2	93	1.5e-34	112.2	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
2918593179	795	64.56	272	794	214	641	1.6e-102	337.9	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918593179	795	77.38	144	219	14	78	4.1e-06	20.6	COG2770	HAMP domain	83
2918593180	237	93.29	3	237	9	272	2.7e-22	73.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918593181	238	97.88	1	187	2	186	7.4e-70	228.7	COG0193	Peptidyl-tRNA hydrolase	190
2918593182	150	70.37	9	147	40	153	5.9e-11	37.5	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918593183	116	95.33	9	115	5	106	9.1e-38	122.9	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
2918593184	367	99.73	1	367	1	371	0.0e+00	500.7	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
2918593185	157	91.19	1	152	13	157	4.9e-42	137.4	COG2030	Acyl dehydratase	159
2918593186	155	86.16	1	155	17	153	3.6e-38	124.9	COG2030	Acyl dehydratase	159
2918593187	202	52.33	2	200	42	187	1.1e-09	33.4	COG0500	SAM-dependent methyltransferase	257
2918593188	180	96.65	1	179	5	177	7.9e-65	212.1	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
2918593189	130	91.85	1	130	1	124	4.8e-28	92.4	COG3791	Uncharacterized conserved protein	133
2918593190	295	96.39	10	294	10	276	3.4e-102	336.2	COG2857	Cytochrome c1	250
2918593191	427	99.51	7	405	2	404	0.0e+00	528.2	COG1290	Cytochrome b subunit of the bc complex	381
2918593192	192	92.78	6	192	3	169	6.4e-59	193.2	COG0723	Rieske Fe-S protein	177
2918593193	303	98.06	1	303	6	309	1.6e-82	271.8	COG3021	Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily	309
2918593194	647	99.49	52	638	3	591	0.0e+00	513	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918593195	616	99.49	22	604	3	591	0.0e+00	507.5	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918593196	291	66.58	5	266	2	264	2.4e-31	103.9	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2918593197	153	96.1	3	153	2	149	2.8e-55	180.9	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
2918593198	550	99.81	1	535	1	534	0.0e+00	662.1	COG1283	Na+/phosphate symporter	533
2918593200	303	91.75	12	303	2	279	1.1e-126	416.3	COG0408	Coproporphyrinogen III oxidase	303
2918593202	61	94.92	1	57	3	58	2.9e-30	99	COG5466	Predicted small metal-binding protein	59
2918593203	418	96.87	6	418	7	408	2.3e-98	324.6	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
2918593204	212	75.58	41	198	16	145	8.3e-24	78.7	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918593205	209	100	1	209	1	206	3.1e-111	364.3	COG3816	Uncharacterized protein	205
2918593206	336	98.48	12	336	4	328	1.2e-99	328.1	COG0714	MoxR-like ATPase	329
2918593207	304	66.91	2	294	138	416	5.4e-68	224.5	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2918593210	137	54.32	4	125	67	154	8.0e-09	30.7	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918593211	317	99	12	310	1	298	2.9e-40	133.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918593212	321	92.69	39	320	3	243	2.4e-32	107	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918593213	437	36.03	290	436	52	189	1.5e-33	25.1	COG0477	MFS family permease	338
2918593213	437	83.81	19	313	8	328	1.5e-33	91	COG0477	MFS family permease	338
2918593214	189	98.25	3	171	2	169	2.1e-55	181.8	COG3153	Predicted N-acetyltransferase YhbS	171
2918593215	347	99.69	18	346	1	321	0.0e+00	526.6	COG0435	Glutathionyl-hydroquinone reductase	324
2918593216	163	79.07	19	162	14	149	3.0e-15	51	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918593217	316	88.61	2	307	1	350	7.9e-43	141.7	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2918593219	569	99.76	39	476	1	412	0.0e+00	442.9	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918593220	392	94.54	1	392	20	400	0.0e+00	442.6	COG3135	Predicted benzoate:H+ symporter BenE	402
2918593221	360	90.05	1	357	39	409	3.2e-64	211.9	COG4222	Uncharacterized conserved protein	391
2918593222	214	100	2	214	1	213	9.3e-87	284.8	COG4944	Uncharacterized protein	213
2918593223	182	94.62	9	182	4	179	1.1e-32	107.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918593225	193	88.5	1	193	18	194	8.0e-69	226.1	COG0740	ATP-dependent protease ClpP, protease subunit	200
2918593226	196	95.52	1	196	8	199	7.8e-68	222.3	COG2370	Hydrogenase/urease accessory protein HupE	201
2918593227	248	100	1	247	1	237	1.2e-95	314.6	COG3416	Uncharacterized protein	233
2918593228	154	97.99	1	147	3	148	4.2e-56	183.3	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
2918593229	300	97.05	1	299	3	298	1.3e-102	337.6	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2918593230	133	75.34	20	131	12	121	1.3e-05	20.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918593231	368	95.08	9	367	8	355	3.0e-88	290.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918593233	106	83.05	4	104	10	107	9.3e-21	68.9	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918593234	348	87.11	1	347	2	339	0.0e+00	464.6	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
2918593235	283	93.13	2	282	7	277	7.4e-113	371	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
2918593236	284	89.18	1	270	33	304	7.6e-95	311.9	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
2918593238	193	95.52	1	193	3	194	7.8e-75	245.6	COG1435	Thymidine kinase	201
2918593239	150	92.19	1	119	11	128	1.1e-35	117.2	COG3794	Plastocyanin	128
2918593240	385	99.72	12	385	2	358	0.0e+00	632.5	COG5345	Uncharacterized protein	358
2918593241	238	86.25	165	237	12	80	5.7e-28	90.3	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918593242	173	98.22	1	170	2	167	2.2e-56	184.9	COG2862	Uncharacterized membrane protein YqhA	169
2918593243	746	99.37	4	746	6	795	6.1e-92	304.2	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918593244	314	99.67	1	314	2	300	1.9e-99	327.8	COG3921	Uncharacterized conserved protein	300
2918593246	729	97.91	528	720	3	189	2.2e-61	200.6	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
2918593246	729	98.72	21	515	5	465	7.4e-129	425.4	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2918593247	170	87.17	1	168	16	178	1.8e-21	71.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918593248	273	49.43	10	270	147	320	1.4e-74	246.1	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2918593249	564	98.12	1	564	8	580	0.0e+00	774.7	COG1001	Adenine deaminase	584
2918593250	150	74.69	5	145	39	159	1.3e-09	33.2	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918593251	554	98.07	21	526	1	507	0.0e+00	486.3	COG0366	Glycosidase	505
2918593252	306	94.94	4	305	2	301	5.9e-62	204	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918593253	349	97.31	2	337	3	400	4.9e-28	93.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918593256	476	99.1	1	470	4	444	0.0e+00	568	COG1160	Predicted GTPases	444
2918593257	223	100	3	223	1	221	4.8e-109	357.5	COG4649	Uncharacterized protein	221
2918593258	194	99.54	1	194	1	218	9.1e-69	225.7	COG4094	Uncharacterized membrane protein	219
2918593259	327	27.24	18	228	110	182	1.3e-06	22.1	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918593260	425	100	1	411	1	405	0.0e+00	623.2	COG1133	ABC-type long-chain fatty acid transport system, fused permease and ATPase components	405
2918593261	396	49.35	210	395	7	195	1.6e-10	12.5	COG0477	MFS family permease	338
2918593261	396	81.2	8	275	10	320	1.6e-10	26.4	COG0477	MFS family permease	338
2918593262	250	97.42	1	250	5	306	1.0e-64	212.6	COG0024	Methionine aminopeptidase	255
2918593263	353	95.34	10	338	15	341	4.6e-62	204.5	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918593264	258	98.13	1	257	5	267	3.6e-78	257.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918593265	489	98.58	1	489	7	492	0.0e+00	837.2	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
2918593266	779	98.98	1	779	4	776	0.0e+00	1473.5	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
2918593267	284	97.01	2	284	7	298	1.2e-76	252.4	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2918593268	309	98.34	7	299	2	297	3.8e-63	208.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918593270	420	99.51	3	412	2	407	0.0e+00	727.1	COG3748	Uncharacterized membrane protein	407
2918593271	436	99.06	1	435	1	420	9.2e-124	407.5	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918593272	249	97.68	3	249	4	256	1.2e-28	94.6	COG0730	Uncharacterized membrane protein YfcA	258
2918593273	377	96.4	7	377	2	349	0.0e+00	459.3	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2918593274	114	96.23	5	110	4	105	5.3e-34	111.3	COG2076	Multidrug transporter EmrE and related cation transporters	106
2918593275	190	37.8	1	188	12	90	2.3e-21	71.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918593276	430	91.09	4	392	20	377	9.7e-117	384.6	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2918593277	247	79.11	60	240	23	147	1.6e-13	45.5	COG0639	Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family	155
2918593278	118	92.74	1	118	10	124	1.3e-51	168.3	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
2918593279	166	96.43	2	166	3	164	2.5e-70	229.7	COG3194	Ureidoglycolate hydrolase (allantoin degradation)	168
2918593280	120	96.58	1	120	4	116	3.2e-37	121.3	COG2361	Uncharacterized conserved protein, contains HEPN domain	117
2918593281	100	100	4	100	1	97	1.2e-26	87.1	COG1669	Predicted nucleotidyltransferase	97
2918593282	165	90.91	1	165	14	173	1.1e-72	238.1	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
2918593283	324	98.88	21	319	4	268	6.2e-52	170.9	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918593285	402	95.62	17	395	4	374	1.2e-43	144.1	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918593286	251	92.52	19	251	9	243	3.5e-81	266.6	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
2918593287	1224	68.53	544	905	122	391	6.4e-72	236.1	COG0642	Signal transduction histidine kinase	336
2918593287	1224	90.23	913	1048	7	126	9.1e-61	80	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918593287	1224	92.48	1087	1217	7	129	9.1e-61	115.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918593288	490	88.08	1	490	30	487	0.0e+00	524.7	COG0513	Superfamily II DNA and RNA helicase	513
2918593289	302	98.01	3	298	3	297	3.0e-49	162.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918593290	129	91.67	1	129	8	139	1.4e-32	107.3	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918593291	205	76.45	13	205	55	239	9.0e-62	203.7	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2918593292	298	95.35	1	294	10	296	2.7e-36	119.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918593293	469	95.9	1	469	11	478	0.0e+00	734.6	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
2918593294	313	98.72	1	313	1	309	1.0e-114	377.7	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2918593295	272	91.72	1	267	11	320	2.3e-56	185.3	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2918593296	198	55.56	3	195	43	197	3.6e-07	25.1	COG0500	SAM-dependent methyltransferase	257
2918593297	154	48.54	32	147	44	126	9.9e-11	36.1	COG3153	Predicted N-acetyltransferase YhbS	171
2918593298	136	95.89	7	129	6	145	4.4e-18	61.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918593299	217	96.17	1	208	2	202	2.3e-35	116.5	COG0406	Broad specificity phosphatase PhoE	208
2918593300	331	99.1	1	331	4	333	0.0e+00	592.8	COG3802	Uncharacterized protein	333
2918593301	398	98.98	2	398	4	393	0.0e+00	532.5	COG4214	ABC-type xylose transport system, permease component	394
2918593302	512	99	1	507	5	500	0.0e+00	624.1	COG1129	ABC-type sugar transport system, ATPase component	500
2918593303	354	99.41	1	354	1	339	0.0e+00	476.6	COG4213	ABC-type xylose transport system, periplasmic component	341
2918593304	304	97.67	1	303	4	297	8.1e-54	177.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918593307	168	93.23	33	168	8	131	8.3e-24	78.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918593309	469	85.07	35	414	18	302	1.3e-16	55.2	COG0582	Integrase	309
2918593310	550	84.96	11	250	2	193	3.6e-17	57.4	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2918593311	287	52.58	2	257	2	205	2.1e-43	143.5	COG1344	Flagellin and related hook-associated protein FlgL	360
2918593312	283	52.06	18	283	187	388	6.3e-23	76.2	COG1344	Flagellin and related hook-associated protein FlgL	360
2918593313	308	95.33	42	301	11	255	6.4e-09	28.6	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918593321	227	53.87	12	195	16	196	2.1e-21	70.5	COG0470	DNA polymerase III, delta prime subunit	324
2918593326	189	57.01	1	189	135	325	3.7e-22	73.8	COG0582	Integrase	309
2918593329	756	15.51	365	460	127	173	1.7e-29	2.1	COG0863	DNA modification methylase	302
2918593329	756	86.47	494	752	7	268	1.7e-29	92.8	COG0863	DNA modification methylase	302
2918593332	648	28.24	66	305	44	163	8.4e-105	23.9	COG0840	Methyl-accepting chemotaxis protein	408
2918593332	648	76	292	594	103	425	8.4e-105	327.9	COG0840	Methyl-accepting chemotaxis protein	408
2918593333	400	48.04	201	398	7	190	1.5e-31	28.3	COG0477	MFS family permease	338
2918593333	400	49.35	3	193	7	195	1.5e-31	81.6	COG0477	MFS family permease	338
2918593334	190	78.26	6	185	3	146	2.6e-33	109.7	COG0431	NAD(P)H-dependent FMN reductase	184
2918593335	303	97.33	1	302	8	299	2.9e-89	293.7	COG2040	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)	300
2918593336	229	98.25	1	229	1	224	3.1e-86	282.9	COG4160	ABC-type arginine/histidine transport system, permease component	228
2918593337	240	97.39	14	238	4	227	6.5e-84	275	COG4215	ABC-type arginine transport system, permease component	230
2918593338	256	96.47	1	256	4	276	5.8e-62	204	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918593339	259	98.44	3	258	3	254	0.0e+00	457.8	COG4598	ABC-type histidine transport system, ATPase component	256
2918593340	452	94.64	2	438	16	421	4.5e-76	250.7	COG3307	O-antigen ligase	424
2918593343	356	97.45	1	356	8	351	5.5e-126	414.7	COG3693	Endo-1,4-beta-xylanase, GH35 family	345
2918593344	303	49.3	2	281	5	181	1.9e-27	91.7	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918593345	314	39.28	4	256	2	142	1.8e-12	42.1	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918593347	271	96.44	4	268	8	251	6.1e-89	291.7	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
2918593349	540	96.13	69	532	7	453	2.8e-115	379.8	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918593350	471	96.65	1	471	12	473	2.1e-90	298.2	COG1109	Phosphomannomutase	464
2918593351	98	100	1	97	1	97	2.7e-24	79.6	COG1669	Predicted nucleotidyltransferase	97
2918593352	117	96.58	1	117	3	115	3.6e-27	88.9	COG2361	Uncharacterized conserved protein, contains HEPN domain	117
2918593353	133	96.24	1	133	2	129	2.3e-47	154.9	COG2346	Truncated hemoglobin YjbI	133
2918593354	131	93.55	11	131	7	122	2.7e-30	99.5	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
2918593356	141	66.02	35	139	4	71	1.4e-03	13.1	COG4378	Uncharacterized protein	103
2918593357	213	90.91	1	211	11	200	7.9e-32	105.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918593358	415	99.04	11	413	4	417	9.3e-65	213.6	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918593359	485	98.84	2	446	3	428	0.0e+00	458.4	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2918593360	147	76.74	2	145	18	149	1.4e-18	61.7	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918593361	264	97.21	7	263	4	247	1.7e-91	300.6	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918593362	291	96.51	24	291	8	256	4.1e-69	227.4	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918593363	290	97.29	29	286	6	256	3.9e-71	233.8	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918593364	330	94.33	1	330	6	321	1.8e-47	156.5	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918593365	397	91.54	4	391	14	370	1.3e-41	137.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918593366	1106	99.9	2	1034	1	1013	0.0e+00	1037	COG0841	Multidrug efflux pump subunit AcrB	1009
2918593367	260	90.83	37	253	10	207	6.7e-35	114.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918593368	274	79.62	21	272	24	230	2.3e-30	100.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918593369	203	95.96	1	203	6	195	1.0e-76	251.2	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
2918593370	223	98.69	4	223	4	229	1.8e-69	228.7	COG0830	Urease accessory protein UreF	229
2918593371	161	100	1	160	1	156	1.0e-49	162.3	COG2371	Urease accessory protein UreE	155
2918593372	178	97.59	1	172	5	166	9.9e-75	243.9	COG0678	Peroxiredoxin	165
2918593374	569	99.82	2	569	2	569	0.0e+00	1067.4	COG0804	Urease alpha subunit	568
2918593377	138	93.75	5	138	7	126	1.0e-38	126.5	COG3755	Uncharacterized conserved protein YecT, DUF1311 family	127
2918593378	118	79.26	2	117	3	109	1.6e-33	109.8	COG3791	Uncharacterized conserved protein	133
2918593379	101	95.28	1	101	1	101	5.0e-51	165.7	COG0832	Urease beta subunit	106
2918593380	85	98.81	2	85	2	84	2.5e-45	147.1	COG3813	Uncharacterized protein	84
2918593381	100	100	1	100	1	100	1.4e-53	173.6	COG0831	Urease gamma subunit	100
2918593382	283	99.26	19	281	3	272	5.6e-81	266.4	COG0829	Urease accessory protein UreH	269
2918593383	417	99.04	10	363	2	311	2.2e-114	375.8	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2918593384	231	96.2	1	231	3	230	1.8e-87	286.8	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918593386	253	98.05	1	253	3	253	2.2e-128	421.5	COG4674	ABC-type uncharacterized transport system, ATPase component	249
2918593387	390	97.21	12	362	6	319	2.6e-91	300.5	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918593388	537	98.01	238	535	5	299	1.9e-105	346.4	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918593389	429	98.36	21	389	2	361	9.7e-73	239.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918593391	344	77.13	1	336	17	360	2.7e-80	264.5	COG0174	Glutamine synthetase	443
2918593392	256	99.25	7	254	2	267	9.1e-65	213.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918593393	1131	61.54	914	1045	6	117	5.0e-07	23.4	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918593393	1131	85.53	545	905	56	392	1.3e-70	232.2	COG0642	Signal transduction histidine kinase	336
2918593393	1131	90.18	33	494	41	444	2.1e-10	34.3	COG1457	Purine-cytosine permease or related protein	442
2918593394	309	99.14	11	282	2	231	4.3e-55	180.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918593395	174	96.72	1	173	7	183	3.5e-69	226.4	COG3911	Predicted ATPase	183
2918593396	235	76.49	6	235	51	255	4.8e-46	151.6	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918593397	372	96.72	8	371	10	363	9.6e-96	315.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918593399	242	99.16	4	239	2	236	1.1e-101	333.3	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918593400	285	98.82	6	267	3	253	1.6e-102	336.4	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918593401	465	98.45	104	449	3	320	1.5e-104	344.3	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918593402	300	99.34	1	299	2	300	5.0e-97	319.4	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918593403	262	94.93	1	262	8	269	8.2e-87	285.3	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
2918593406	93	93.94	1	93	6	98	5.9e-31	101.1	COG2388	Predicted acetyltransferase, GNAT superfamily	99
2918593407	67	50.85	1	56	14	43	1.4e-06	23.1	COG5466	Predicted small metal-binding protein	59
2918593408	116	6.93	2	112	907	987	1.1e-04	14.1	COG1196	Chromosome segregation ATPase	1163
2918593409	234	99.57	1	225	1	231	6.4e-72	236	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918593410	171	83.96	2	166	5	161	2.2e-28	93.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918593411	348	89.76	8	348	29	361	1.2e-75	249.1	COG4188	Predicted dienelactone hydrolase	365
2918593412	175	79.68	1	171	7	155	1.5e-21	71.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918593413	215	99.07	1	214	1	212	4.0e-114	373.7	COG5385	Uncharacterized protein	214
2918593414	196	96.1	1	196	9	205	1.8e-106	348.4	COG5400	Uncharacterized protein	205
2918593415	409	16.44	46	347	755	946	1.6e-04	12.7	COG1196	Chromosome segregation ATPase	1163
2918593416	284	96.58	17	280	3	256	1.4e-55	182.7	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2918593418	340	96.92	10	329	9	291	4.6e-94	309.4	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2918593419	274	56.27	4	268	31	187	3.3e-04	15.5	COG0500	SAM-dependent methyltransferase	257
2918593420	300	80.06	2	296	64	336	2.2e-93	307.8	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918593422	432	99.77	1	431	1	429	0.0e+00	626.5	COG0104	Adenylosuccinate synthase	430
2918593423	295	96.01	2	294	8	296	6.3e-46	151.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918593424	177	82.2	12	176	7	163	1.8e-35	116.7	COG3672	Predicted transglutaminase-like cysteine proteinase	191
2918593425	194	96.45	1	194	7	196	7.6e-109	356.5	COG4764	Uncharacterized protein	197
2918593426	204	98.09	1	204	2	206	6.5e-64	209.7	COG0400	Predicted esterase	207
2918593427	314	100	6	270	1	146	8.0e-36	114.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918593428	356	98.12	89	356	5	265	3.0e-71	234.1	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
2918593429	237	99.1	6	227	2	221	5.6e-98	321.4	COG0692	Uracil DNA glycosylase	223
2918593430	131	98.63	2	125	2	145	7.9e-14	47.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918593431	118	98.32	1	118	2	118	7.4e-48	156	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
2918593432	260	100	1	257	1	259	1.7e-106	349.4	COG4559	ABC-type hemin transport system, ATPase component	259
2918593433	362	97.61	15	356	5	331	3.0e-98	323.1	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918593434	297	95.67	1	295	13	299	1.6e-109	359.7	COG4558	ABC-type hemin transport system, periplasmic component	300
2918593435	115	96.23	1	109	2	103	7.5e-34	110.3	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
2918593436	174	96.02	1	174	7	175	3.8e-76	249	COG3721	Putative heme iron utilization protein	176
2918593439	80	90.41	1	71	2	67	1.5e-33	109	COG3655	DNA-binding transcriptional regulator, XRE family	73
2918593440	258	74.21	1	147	31	148	7.6e-47	153.1	COG3126	Uncharacterized lipoprotein YbaY	158
2918593441	294	97.91	1	282	6	286	0.0e+00	438.6	COG0788	Formyltetrahydrofolate hydrolase	287
2918593442	79	75	1	79	25	99	1.2e-36	119.4	COG3657	Putative component of the toxin-antitoxin plasmid stabilization module	100
2918593443	101	90	1	97	8	97	9.2e-32	103.4	COG3636	DNA-binding prophage protein	100
2918593444	464	91.12	44	458	25	383	2.2e-50	166.5	COG0642	Signal transduction histidine kinase	336
2918593445	226	98.71	1	222	2	230	4.7e-71	233.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918593446	355	99.34	50	355	1	299	9.0e-57	187.1	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918593447	314	96.87	1	314	11	319	2.2e-110	363.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918593449	505	99.6	1	504	1	502	0.0e+00	690.4	COG3333	TctA family transporter	504
2918593451	312	92.19	1	308	25	319	1.3e-120	396.4	COG4607	ABC-type enterochelin transport system, periplasmic component	320
2918593452	321	97.82	1	321	6	319	0.0e+00	479.2	COG4606	ABC-type enterochelin transport system, permease component	321
2918593453	322	98.42	2	322	4	314	0.0e+00	435.8	COG4605	ABC-type enterochelin transport system, permease component	316
2918593454	252	99.6	1	252	1	251	1.4e-128	422.1	COG4604	ABC-type enterochelin transport system, ATPase component	252
2918593455	162	99.36	3	159	2	157	1.0e-53	175.9	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
2918593458	653	21.65	59	309	78	169	3.0e-103	31	COG0840	Methyl-accepting chemotaxis protein	408
2918593458	653	76.71	292	595	100	425	3.0e-103	316.9	COG0840	Methyl-accepting chemotaxis protein	408
2918593459	277	96.81	1	276	8	280	1.1e-96	317.5	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2918593460	393	97.22	1	388	10	393	0.0e+00	459.7	COG2814	Predicted arabinose efflux permease, MFS family	394
2918593461	299	96.35	5	299	6	295	9.9e-71	233.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918593462	299	96.68	2	297	3	293	8.5e-69	226.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918593463	269	71.7	3	265	63	290	2.0e-45	150	COG0657	Acetyl esterase/lipase	312
2918593464	396	96.92	1	389	4	381	1.2e-71	236.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918593465	1064	99.9	2	1039	1	1013	0.0e+00	1210.8	COG0841	Multidrug efflux pump subunit AcrB	1009
2918593467	281	96.89	36	277	7	255	1.7e-71	235	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918593468	486	99.79	48	486	1	484	4.4e-94	310.2	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918593469	291	99.29	7	283	2	280	4.6e-98	322.2	COG2240	Pyridoxal/pyridoxine/pyridoxamine kinase	281
2918593470	213	97.6	2	213	3	205	9.8e-68	222.4	COG0288	Carbonic anhydrase	207
2918593471	268	8.36	237	268	314	342	2.2e-89	19.1	COG2951	Membrane-bound lytic murein transglycosylase B	343
2918593471	268	68.59	1	240	16	253	2.2e-89	280.2	COG2951	Membrane-bound lytic murein transglycosylase B	343
2918593472	344	99.4	2	332	2	335	0.0e+00	433.9	COG0136	Aspartate-semialdehyde dehydrogenase	334
2918593474	627	27.15	485	622	86	189	1.9e-36	5	COG0477	MFS family permease	338
2918593474	627	98.96	19	339	2	380	1.9e-36	117.4	COG0477	MFS family permease	338
2918593475	523	37.19	383	523	67	201	0.0e+00	63.9	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2918593475	523	100	2	369	1	363	0.0e+00	502.2	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2918593476	477	99.36	1	476	1	467	0.0e+00	702.1	COG1282	NAD/NADP transhydrogenase beta subunit	463
2918593477	174	89.19	9	174	6	170	3.7e-45	148.1	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918593478	196	95.83	6	196	5	211	1.1e-28	95	COG0778	Nitroreductase	207
2918593479	263	94.24	2	259	15	292	4.4e-36	119.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918593480	128	95.59	1	128	5	134	1.2e-32	107.2	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918593481	246	98.54	30	241	2	204	6.6e-53	173.9	COG1335	Nicotinamidase-related amidase	205
2918593482	363	94.75	6	357	17	341	1.3e-70	232.6	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918593483	203	99.49	7	203	2	196	2.5e-84	276.2	COG3230	Heme oxygenase	196
2918593484	294	96.99	1	293	5	294	2.1e-63	208.1	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918593485	218	91.38	1	218	11	222	1.1e-51	169.9	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918593486	443	97.74	6	441	5	437	5.8e-60	198.2	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918593487	309	94.97	10	305	12	294	2.0e-95	313.8	COG1175	ABC-type sugar transport system, permease component	295
2918593488	278	96.82	2	276	10	283	7.0e-74	243.1	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918593489	352	99.71	1	347	1	349	0.0e+00	478.9	COG3839	ABC-type sugar transport system, ATPase component	338
2918593490	320	98.73	10	308	2	313	1.4e-56	186.2	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918593491	352	98.85	10	345	1	344	9.9e-103	338.1	COG3191	L-aminopeptidase/D-esterase	348
2918593492	288	98.95	6	287	2	283	9.0e-74	243.2	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2918593493	298	96.01	1	298	3	291	7.3e-47	154.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918593494	502	85.89	1	437	33	379	8.1e-49	161.2	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918593495	246	98.04	1	246	3	252	6.5e-91	298.7	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
2918593496	276	84.62	2	275	1	275	4.2e-102	335.7	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918593497	300	94.63	10	300	13	294	4.0e-105	345.3	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918593498	339	97.48	6	339	6	315	3.9e-106	349.4	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918593499	531	95.33	1	530	15	565	1.1e-86	286.4	COG0747	ABC-type transport system, periplasmic component	556
2918593500	346	99.37	7	346	2	317	1.7e-111	366.8	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
2918593502	866	96.3	17	328	9	320	1.0e-63	210.2	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2918593502	866	99.45	326	866	4	541	0.0e+00	668.7	COG2898	Lysylphosphatidylglycerol synthetase, C-terminal domain, DUF2156 family	538
2918593503	451	97.18	1	451	9	456	0.0e+00	601.2	COG3946	Type IV secretory pathway, VirJ component	456
2918593505	428	49.35	240	425	6	194	6.3e-39	36.5	COG0477	MFS family permease	338
2918593505	428	75.2	13	288	8	295	6.3e-39	96.8	COG0477	MFS family permease	338
2918593506	112	97.83	9	103	2	91	1.4e-22	74.4	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
2918593507	293	98.68	56	289	1	225	2.7e-54	178.3	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2918593508	351	98.94	4	345	5	379	3.3e-79	259.1	COG1454	Alcohol dehydrogenase, class IV	377
2918593509	327	98.68	3	327	4	303	3.0e-73	241.3	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2918593510	409	91.98	12	407	32	398	3.4e-48	158.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918593511	179	88.11	15	178	11	173	2.4e-40	132.3	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918593512	143	83.46	17	141	16	126	1.4e-22	74.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918593514	209	99.58	4	209	2	236	3.6e-28	93.4	COG3637	Opacity protein and related surface antigens	199
2918593515	465	61.67	1	44	7	43	1.8e-03	11.8	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
2918593515	465	79.7	96	458	60	373	2.4e-45	150.1	COG0642	Signal transduction histidine kinase	336
2918593516	213	93.97	1	213	13	230	3.5e-63	207.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918593517	210	68.9	13	203	19	162	9.1e-17	56.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918593518	678	79.15	383	643	2	244	1.4e-14	45.5	COG0492	Thioredoxin reductase	305
2918593518	678	99.45	1	365	2	362	1.7e-102	337.4	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918593519	353	98.02	5	353	5	350	2.8e-125	412.5	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918593520	743	98.9	154	722	2	539	0.0e+00	545.8	COG1178	ABC-type Fe3+ transport system, permease component	540
2918593521	341	99.34	41	339	2	300	3.0e-86	283.8	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918593522	340	98.67	41	338	1	297	9.0e-68	223.1	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918593523	246	99.14	6	241	2	231	3.5e-66	217.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918593524	701	74.87	389	701	96	390	6.4e-48	158.8	COG0642	Signal transduction histidine kinase	336
2918593525	444	94.39	5	441	25	445	0.0e+00	431.5	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2918593526	282	98.01	2	281	1	295	2.7e-48	159.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918593527	67	98.51	1	67	1	66	4.3e-27	88.4	COG1278	Cold shock protein, CspA family	67
2918593530	296	89.43	1	292	37	349	2.5e-125	412.4	COG3839	ABC-type sugar transport system, ATPase component	338
2918593531	358	99.71	1	351	1	349	0.0e+00	462.9	COG3839	ABC-type sugar transport system, ATPase component	338
2918593532	276	96.47	1	275	11	283	2.9e-85	280.5	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918593533	314	94.3	17	313	12	292	1.2e-91	301.4	COG1175	ABC-type sugar transport system, permease component	295
2918593534	419	98.19	1	415	7	441	2.9e-77	255.3	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918593535	390	95.72	4	388	17	396	1.5e-120	396.9	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2918593536	230	96.27	1	230	4	235	1.8e-58	192.2	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918593537	163	93.59	8	163	3	148	2.5e-41	135.6	COG0328	Ribonuclease HI	154
2918593538	140	56.79	4	127	62	153	3.4e-10	34.9	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918593539	341	96.72	1	340	9	303	6.9e-104	340.8	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
2918593540	288	96.74	2	277	5	271	2.1e-75	247.8	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2918593541	275	96.85	2	247	3	248	8.7e-75	245.6	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
2918593542	401	99.69	5	376	1	325	5.7e-114	375.2	COG0523	GTPase, G3E family	323
2918593543	155	93.79	1	155	6	156	2.8e-52	171.2	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
2918593545	368	99.08	22	361	1	323	6.4e-81	266.6	COG0523	GTPase, G3E family	323
2918593546	434	97.29	2	432	12	442	6.3e-67	221.1	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918593547	293	96.31	2	292	7	293	2.4e-80	264.3	COG1175	ABC-type sugar transport system, permease component	295
2918593548	282	95.76	1	282	9	279	2.1e-80	264.6	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918593549	353	99.71	1	349	1	349	0.0e+00	471.7	COG3839	ABC-type sugar transport system, ATPase component	338
2918593551	232	98.62	18	232	4	218	4.4e-74	243.1	COG3047	Outer membrane protein W	213
2918593552	431	28.44	283	426	80	207	1.1e-20	22.2	COG2271	Sugar phosphate permease	448
2918593552	431	59.78	37	311	50	318	1.1e-20	60.1	COG2271	Sugar phosphate permease	448
2918593553	133	92.48	10	133	5	127	2.5e-19	64	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918593554	189	96.49	14	188	3	167	1.9e-58	191.4	COG3153	Predicted N-acetyltransferase YhbS	171
2918593555	377	94.18	6	377	23	394	1.1e-108	357.7	COG0019	Diaminopimelate decarboxylase	394
2918593558	297	98.34	2	297	2	297	2.4e-68	225.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918593559	317	95.72	1	317	11	323	7.5e-66	216.6	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918593560	333	96.24	13	333	7	313	1.0e-92	304.8	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918593561	507	98.8	6	501	6	500	0.0e+00	618	COG1129	ABC-type sugar transport system, ATPase component	500
2918593562	209	89.47	1	208	3	189	2.5e-25	84.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918593563	1044	99.8	1	1025	2	1013	0.0e+00	1209.9	COG0841	Multidrug efflux pump subunit AcrB	1009
2918593564	396	98.21	1	375	6	388	2.0e-81	268.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918593565	500	43.39	9	156	138	242	1.5e-10	10.7	COG2202	PAS domain	232
2918593565	500	71.07	156	316	71	242	1.5e-10	27.8	COG2202	PAS domain	232
2918593565	500	92.35	304	481	7	175	8.8e-38	123.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918593566	271	99.62	1	271	2	264	0.0e+00	440.2	COG3257	Uncharacterized protein, possibly involved in glyoxylate utilization	264
2918593568	664	72.1	34	658	168	645	1.4e-88	291.9	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918593569	358	98.57	7	356	3	346	4.0e-116	382.1	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
2918593571	536	98.1	2	536	7	573	7.7e-111	366	COG0747	ABC-type transport system, periplasmic component	556
2918593572	329	98.11	4	326	4	315	7.3e-103	338.6	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918593573	276	90.27	2	275	27	295	6.0e-83	272.5	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918593574	267	80	6	262	2	261	4.0e-81	266.7	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918593575	259	47.46	1	258	288	549	1.3e-93	308.9	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918593576	372	88.77	14	366	43	382	8.9e-95	312	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
2918593578	154	31.69	3	112	218	320	3.4e-25	82.8	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918593579	134	95.89	3	132	2	141	1.6e-10	36.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918593580	71	14.65	3	66	296	369	5.7e-04	13	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2918593581	603	98.1	3	587	8	574	0.0e+00	618.5	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918593582	319	98.17	1	318	4	324	6.4e-79	259.5	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918593583	507	99	1	501	4	499	0.0e+00	604.4	COG1129	ABC-type sugar transport system, ATPase component	500
2918593584	347	95.3	3	319	7	310	1.0e-83	275	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918593585	326	94.36	2	319	11	311	5.9e-81	266	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918593586	244	95.85	7	244	6	236	1.7e-62	205.2	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918593587	405	96.46	13	399	5	385	1.8e-105	347	COG2814	Predicted arabinose efflux permease, MFS family	394
2918593588	312	78.79	188	308	22	125	2.8e-26	85.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918593589	212	45.19	15	196	47	154	1.1e-13	45.2	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918593590	1092	93.09	3	1069	2	1078	0.0e+00	1085.3	COG0587	DNA polymerase III, alpha subunit	1139
2918593591	505	11.5	17	74	23	65	2.4e-58	12.8	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918593591	505	99.47	70	463	2	373	2.4e-58	179.4	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918593592	254	96.93	1	254	5	257	2.3e-102	335.9	COG4544	Uncharacterized conserved protein	260
2918593593	117	97.52	1	116	3	120	2.9e-45	147.7	COG3759	Uncharacterized membrane protein	121
2918593594	424	98.82	2	423	5	421	0.0e+00	569.8	COG2379	Glycerate-2-kinase	422
2918593596	395	95.73	12	389	2	337	8.3e-67	220.4	COG0673	Predicted dehydrogenase	342
2918593597	350	99.64	7	325	2	278	1.9e-56	185.8	COG1082	Sugar phosphate isomerase/epimerase	274
2918593598	357	99.71	1	352	1	349	0.0e+00	475	COG3839	ABC-type sugar transport system, ATPase component	338
2918593599	282	96.82	4	281	10	283	2.6e-82	270.7	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918593600	307	96.31	13	307	6	292	6.1e-81	266.3	COG1175	ABC-type sugar transport system, permease component	295
2918593601	433	96.39	9	432	11	437	1.5e-68	226.5	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918593602	399	89.03	79	390	1	276	3.9e-39	128.9	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918593603	366	99.43	1	347	1	349	1.8e-72	239	COG0673	Predicted dehydrogenase	342
2918593604	213	89.54	1	213	3	216	7.7e-119	390.2	COG3828	Type 1 glutamine amidotransferase (GATase1)-like domain	239
2918593605	452	97.09	1	452	7	473	4.3e-120	396.3	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918593606	772	72.7	212	754	159	640	1.5e-121	400.6	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918593607	297	95.05	1	278	11	279	7.4e-48	157.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918593608	300	95.76	1	280	9	279	4.7e-53	174.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918593609	86	93.18	1	84	1	82	8.9e-31	100.1	COG0851	Septum formation topological specificity factor MinE	88
2918593610	271	99.26	1	271	1	270	3.2e-129	424.2	COG2894	Septum formation inhibitor-activating ATPase MinD	272
2918593611	242	98.25	10	242	3	227	1.4e-66	219.2	COG0850	Septum formation inhibitor MinC	219
2918593612	228	86.88	15	223	2	193	1.8e-49	162.9	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2918593614	238	95.44	1	234	5	234	2.8e-65	214.4	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918593615	324	97.89	1	324	5	329	1.4e-103	341	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918593616	190	96.05	18	190	2	171	5.4e-52	170.1	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918593617	468	99.47	45	466	1	377	0.0e+00	510.7	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918593618	348	99.15	3	345	4	353	1.6e-95	314.1	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918593619	402	99.17	1	396	1	359	0.0e+00	503.1	COG1312	D-mannonate dehydratase	362
2918593620	116	39.33	28	115	78	136	1.8e-05	19.2	COG5652	VanZ like family protein (function unknown)	148
2918593621	503	98.96	7	496	2	475	1.8e-83	274.9	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918593623	332	97.29	7	332	5	327	4.3e-92	303.2	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918593624	610	83.62	17	204	3	150	1.4e-33	110.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918593624	610	96.57	244	610	2	367	8.6e-108	355.1	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918593625	375	93.88	9	355	17	338	5.2e-78	256.8	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918593626	283	72.84	20	275	68	311	1.5e-24	79	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918593627	121	79.66	12	112	14	107	1.9e-15	51.6	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918593628	209	95.81	1	206	1	206	6.2e-52	170.9	COG0625	Glutathione S-transferase	211
2918593629	611	99.28	10	571	4	551	0.0e+00	761.2	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918593630	398	95.44	1	388	10	386	4.6e-122	401.9	COG1921	Seryl-tRNA(Sec) selenium transferase	395
2918593631	278	99.59	32	275	2	246	3.0e-61	200.8	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918593632	164	94.85	17	164	7	135	1.2e-23	77.9	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918593633	407	99.74	10	406	2	386	0.0e+00	599.7	COG3964	Predicted amidohydrolase	386
2918593634	291	94.3	4	290	17	297	2.5e-102	336.2	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918593635	313	99.06	1	313	2	316	2.6e-115	379.6	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918593636	508	94.98	2	508	24	572	6.7e-92	303.5	COG0747	ABC-type transport system, periplasmic component	556
2918593637	374	81.17	2	372	71	402	1.8e-36	120.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918593638	398	14.06	266	314	145	179	8.3e-48	9	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918593638	398	83.53	41	292	40	247	8.3e-48	154.4	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918593639	425	88.97	2	404	34	380	1.9e-61	202.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918593640	1046	99.8	1	1012	2	1013	0.0e+00	1093.7	COG0841	Multidrug efflux pump subunit AcrB	1009
2918593641	193	94.48	1	193	9	179	3.0e-47	154.9	COG5342	Invasion protein IalB, involved in pathogenesis	181
2918593642	1374	21.15	671	792	1	125	0.0e+00	27.9	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
2918593642	1374	92.22	776	1374	47	591	0.0e+00	456.3	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
2918593643	174	82.7	7	169	8	160	1.8e-42	139.3	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918593644	297	100	1	297	1	298	2.0e-122	402.3	COG4989	Predicted oxidoreductase	298
2918593645	385	94.46	20	366	17	340	5.1e-67	220.6	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918593646	234	97.07	1	233	6	237	8.4e-44	144.2	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918593647	358	99.71	1	352	1	349	0.0e+00	473.9	COG3839	ABC-type sugar transport system, ATPase component	338
2918593648	416	98.87	1	416	3	440	4.8e-79	261.2	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918593649	308	95.3	14	308	10	293	1.5e-93	307.8	COG1175	ABC-type sugar transport system, permease component	295
2918593650	284	94.7	10	283	16	283	1.4e-79	261.7	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918593651	664	84.82	1	664	16	680	0.0e+00	500.4	COG1501	Alpha-glucosidase, glycosyl hydrolase family GH31	772
2918593654	261	94.57	1	247	13	256	2.2e-66	218.3	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918593655	316	93.43	1	313	6	318	3.1e-59	195.2	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918593656	246	40	136	244	159	264	5.2e-77	109.5	COG2145	Hydroxyethylthiazole kinase, sugar kinase family	265
2918593656	246	47.17	9	142	3	127	5.2e-77	142.5	COG2145	Hydroxyethylthiazole kinase, sugar kinase family	265
2918593657	220	98.58	1	216	2	209	5.2e-67	219.4	COG0352	Thiamine monophosphate synthase	211
2918593658	265	98.48	1	264	4	262	5.1e-102	334.9	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
2918593659	152	93.04	1	150	3	149	4.8e-37	121.8	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918593660	388	98.35	13	373	6	363	2.6e-117	386.1	COG0787	Alanine racemase	360
2918593661	418	96.65	1	418	5	379	2.6e-95	314.3	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918593662	236	93.1	3	231	10	225	1.1e-60	199.1	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918593664	454	98.5	1	451	5	464	0.0e+00	560.5	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918593665	613	99.5	11	613	3	603	0.0e+00	721.2	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2918593666	448	98.56	13	438	2	413	0.0e+00	533.4	COG1301	Na+/H+-dicarboxylate symporter	415
2918593667	450	98.21	4	449	6	444	0.0e+00	487	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918593668	244	97.01	4	243	8	267	4.6e-60	197.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918593669	548	22.35	433	512	187	245	2.9e-08	11.4	COG1729	Periplasmic TolA-binding protein (function unknown)	262
2918593669	548	25.38	266	426	140	206	2.9e-08	15.5	COG1729	Periplasmic TolA-binding protein (function unknown)	262
2918593670	384	96.44	1	383	10	388	4.6e-95	313.2	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2918593671	780	41.3	562	768	62	213	2.7e-08	20.4	COG0457	Tetratricopeptide (TPR) repeat	291
2918593671	780	49.18	114	594	107	287	2.7e-08	12.3	COG0457	Tetratricopeptide (TPR) repeat	291
2918593672	351	95.56	7	351	4	347	2.2e-120	396.3	COG3405	Endo-1,4-beta-D-glucanase Y	360
2918593674	729	90.89	72	558	4	462	2.2e-81	268.6	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2918593676	394	98.97	8	394	3	386	0.0e+00	483.8	COG2942	Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family	388
2918593677	320	92.16	1	320	24	352	6.4e-116	382	COG4124	Beta-mannanase	355
2918593679	645	91.09	51	458	4	463	2.3e-47	156	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2918593680	327	96.05	3	321	2	317	4.2e-129	424.4	COG1087	UDP-glucose 4-epimerase	329
2918593681	340	97.82	20	332	3	316	1.0e-76	252.8	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918593683	257	96.68	21	247	3	206	1.0e-38	127.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918593686	734	97.59	160	733	3	568	0.0e+00	782.7	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2918593687	452	98.46	20	443	6	389	7.4e-40	131.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918593689	422	97.44	1	411	1	418	1.2e-76	252.6	COG3307	O-antigen ligase	424
2918593690	419	7.23	343	414	41	58	3.4e-55	1.7	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918593690	419	92.37	1	254	17	246	3.4e-55	177.7	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918593691	226	92.89	1	226	17	225	9.0e-80	261.5	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2918593692	182	77.69	4	148	2	102	1.6e-17	58.7	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918593693	444	97.54	3	444	7	442	0.0e+00	516.8	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918593694	606	25.41	54	297	36	143	6.4e-99	15.7	COG0840	Methyl-accepting chemotaxis protein	408
2918593694	606	76	288	591	103	425	6.4e-99	315.3	COG0840	Methyl-accepting chemotaxis protein	408
2918593695	261	95.45	5	225	9	239	4.4e-70	230.6	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2918593696	328	98	1	305	7	300	2.7e-114	375.9	COG3034	Murein L,D-transpeptidase YafK	298
2918593697	259	98.51	1	257	4	267	1.5e-63	209.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918593699	193	95	4	192	6	195	9.1e-70	228.2	COG2094	3-methyladenine DNA glycosylase Mpg	200
2918593701	47	14.87	2	47	223	262	8.5e-02	6.8	COG4278	Uncharacterized protein	269
2918593703	337	99.1	1	337	2	332	6.8e-94	309.2	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918593704	421	95.03	1	419	18	438	7.1e-75	247.4	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918593705	324	96.31	16	322	8	294	6.6e-95	312	COG1175	ABC-type sugar transport system, permease component	295
2918593706	277	96.82	2	276	10	283	6.8e-80	262.7	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918593707	342	99.71	1	329	1	349	0.0e+00	453.5	COG3839	ABC-type sugar transport system, ATPase component	338
2918593708	261	100	1	261	1	261	0.0e+00	522.7	COG4813	Trehalose utilization protein	261
2918593709	349	98.86	1	349	4	350	1.8e-77	255.4	COG0673	Predicted dehydrogenase	342
2918593710	251	99.08	12	247	3	217	4.4e-59	194.6	COG0602	Organic radical activating enzyme	212
2918593711	118	74.34	1	118	2	114	1.0e-34	114.1	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
2918593712	236	98.65	1	220	3	221	1.5e-79	260.8	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
2918593714	56	7.47	2	50	357	393	1.4e-03	11.8	COG3428	Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain	494
2918593715	377	98.29	2	359	4	348	7.3e-71	233.6	COG0673	Predicted dehydrogenase	342
2918593716	254	93.88	3	254	13	273	2.4e-35	116.6	COG1082	Sugar phosphate isomerase/epimerase	274
2918593717	362	99.43	2	357	2	349	0.0e+00	442.2	COG3839	ABC-type sugar transport system, ATPase component	338
2918593718	313	98.23	25	312	6	283	5.4e-80	263	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918593719	300	92.62	7	299	13	288	1.3e-70	232.3	COG1175	ABC-type sugar transport system, permease component	295
2918593720	408	96.39	1	407	7	433	1.9e-51	170.2	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918593721	240	87.39	1	237	13	213	3.9e-11	36.8	COG1266	Membrane protease YdiL, CAAX protease family	226
2918593722	476	91.47	348	474	11	128	7.5e-40	129.1	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2918593722	476	99.7	7	338	1	334	1.8e-123	406.4	COG0836	Mannose-1-phosphate guanylyltransferase	333
2918593723	809	100	14	809	1	773	0.0e+00	1080.5	COG4993	Glucose dehydrogenase	773
2918593724	299	98.34	1	299	1	296	4.0e-59	195.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918593725	762	96.15	1	442	9	433	0.0e+00	591.3	COG0281	Malic enzyme	432
2918593725	762	98.78	439	762	2	324	2.9e-120	395.4	COG0280	Phosphotransacetylase	327
2918593726	279	92.23	1	270	8	268	6.2e-51	167.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918593727	247	91.67	8	244	18	226	9.0e-53	173.5	COG0765	ABC-type amino acid transport system, permease component	222
2918593728	260	92.54	20	260	15	225	2.6e-61	201.4	COG0765	ABC-type amino acid transport system, permease component	222
2918593729	266	98.35	12	254	2	239	3.6e-103	338.1	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918593730	448	95.83	2	448	9	445	1.1e-105	348.1	COG2079	2-methylcitrate dehydratase PrpD	453
2918593731	436	98.25	15	416	6	342	2.3e-101	333.6	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918593732	577	81.88	17	546	78	425	1.5e-101	335.1	COG0840	Methyl-accepting chemotaxis protein	408
2918593733	417	97.68	3	417	4	382	1.8e-75	248.7	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918593736	179	97.25	1	179	1	177	1.2e-78	257.2	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
2918593737	489	99.11	1	445	3	445	0.0e+00	676.3	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
2918593738	365	99.72	1	358	1	362	0.0e+00	597.1	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
2918593739	251	98.77	1	249	1	241	1.2e-86	284.5	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
2918593740	343	97.49	16	343	6	316	5.8e-103	338.4	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918593741	513	98.8	16	513	5	499	0.0e+00	677.4	COG1129	ABC-type sugar transport system, ATPase component	500
2918593742	309	93.58	1	309	18	323	2.1e-87	287.4	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918593744	480	99.24	6	455	2	391	3.0e-114	376.4	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2918593745	514	96.02	2	514	17	571	1.3e-101	335.6	COG0747	ABC-type transport system, periplasmic component	556
2918593746	278	84.73	1	278	49	331	5.0e-75	247.2	COG2367	Beta-lactamase class A	329
2918593747	544	99.28	1	529	4	551	0.0e+00	666	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918593748	272	90.6	1	270	27	296	8.0e-96	314.7	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918593749	314	98.74	1	314	1	314	1.9e-110	363.5	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918593750	301	98.34	1	299	1	296	5.0e-53	175.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918593751	314	99.35	1	306	1	306	2.9e-107	353	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
2918593752	512	22.83	376	511	520	674	4.1e-103	12.5	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2918593752	512	58.32	1	389	3	398	4.1e-103	330.2	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2918593753	358	99.44	1	358	2	356	0.0e+00	497.5	COG3535	Uncharacterized conserved protein, DUF917 family	357
2918593754	531	96.02	4	527	15	569	2.2e-90	298.3	COG0747	ABC-type transport system, periplasmic component	556
2918593755	377	99.16	13	371	2	355	0.0e+00	506	COG3535	Uncharacterized conserved protein, DUF917 family	357
2918593756	518	24.74	363	516	509	676	1.1e-109	25.8	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2918593756	518	59.2	1	392	3	404	1.1e-109	341.7	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2918593757	548	99.46	1	526	1	549	0.0e+00	620.1	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918593758	293	94.3	4	293	13	293	1.1e-94	311.1	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918593759	342	98.43	5	340	5	317	1.6e-98	324.3	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918593760	783	82.5	708	783	13	78	1.9e-23	74.8	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918593761	236	98.58	1	223	3	211	1.2e-67	221.9	COG0684	Regulator of RNase E activity RraA	210
2918593763	574	98.1	1	562	10	576	0.0e+00	631	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918593764	359	99.71	1	351	1	349	0.0e+00	455.7	COG3839	ABC-type sugar transport system, ATPase component	338
2918593765	347	98.94	9	347	4	283	9.7e-99	324.6	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918593766	322	95.97	19	322	8	293	9.0e-87	285.4	COG1175	ABC-type sugar transport system, permease component	295
2918593767	423	98.87	1	423	5	442	8.6e-59	194.4	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918593768	357	99.15	1	339	3	350	4.4e-75	247.6	COG0673	Predicted dehydrogenase	342
2918593769	338	65.53	2	335	38	267	2.2e-46	153.3	COG0673	Predicted dehydrogenase	342
2918593770	350	98.86	2	349	4	350	7.2e-67	220.6	COG0673	Predicted dehydrogenase	342
2918593771	237	96.12	8	237	7	229	2.8e-56	184.8	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918593772	306	96.76	2	302	11	309	1.1e-80	265.2	COG3386	Sugar lactone lactonase YvrE	307
2918593773	437	98.21	8	428	8	390	2.0e-39	130	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918593774	615	98.1	2	584	3	571	0.0e+00	862.9	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2918593776	930	98.11	107	930	16	795	1.4e-65	217	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918593777	331	97.52	3	330	7	321	6.9e-99	325	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918593778	166	85.48	2	166	19	177	5.4e-34	111.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918593779	250	98.06	2	249	3	255	4.4e-68	223.6	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
2918593780	355	98.51	16	354	5	334	3.6e-91	299.9	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918593781	379	96.6	1	346	12	324	1.2e-57	190	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2918593782	377	96.6	1	346	12	324	3.9e-65	214.6	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2918593783	274	69.87	6	210	10	176	8.6e-31	100.9	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918593784	159	93.75	3	130	9	128	1.9e-31	103.3	COG3794	Plastocyanin	128
2918593785	266	95.74	1	257	1	247	1.6e-89	293.8	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
2918593786	342	97.61	7	342	8	334	9.3e-94	308.4	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918593787	343	90.74	8	342	26	319	1.9e-58	192.4	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2918593789	292	81.48	8	143	25	156	1.6e-06	20.8	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918593790	374	96.17	1	374	14	415	7.3e-84	276.6	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918593791	307	88.04	1	307	40	326	8.4e-84	275.5	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918593792	118	97.41	1	117	3	115	2.8e-42	137.7	COG3450	Predicted enzyme of the cupin superfamily	116
2918593793	151	85.8	1	144	20	158	2.0e-05	19.4	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918593794	680	99.85	1	678	1	678	0.0e+00	583.6	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2918593795	655	98.76	2	575	2	559	0.0e+00	492.7	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
2918593796	487	98.75	14	487	2	474	0.0e+00	514.5	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918593797	347	98.85	1	347	2	345	1.3e-127	419.9	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2918593798	485	98.33	12	484	4	474	0.0e+00	585.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918593799	424	96.91	22	404	3	378	4.5e-80	264	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918593800	222	96.97	3	222	3	226	1.3e-32	107.9	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918593801	278	74.85	4	140	6	133	1.3e-13	41.1	COG3153	Predicted N-acetyltransferase YhbS	171
2918593802	457	98.66	1	451	4	444	0.0e+00	505.3	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918593803	237	97.84	5	234	2	227	2.6e-34	113.2	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918593804	536	97.4	20	533	7	569	6.8e-93	306.6	COG0747	ABC-type transport system, periplasmic component	556
2918593805	316	98.43	2	316	3	315	1.4e-91	301.5	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918593806	283	91.61	2	283	23	295	2.5e-70	231.1	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918593807	551	99.46	1	533	3	551	0.0e+00	614.5	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918593808	159	93.04	1	158	4	150	2.7e-41	135.6	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918593809	441	98.45	14	434	2	383	8.7e-107	351.9	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918593810	383	98.45	5	380	4	385	3.4e-80	264.5	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918593811	460	16.51	4	105	148	218	9.2e-30	36	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918593811	460	71.86	77	452	91	399	9.2e-30	65.9	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918593812	103	7.36	11	96	7	78	1.5e-05	17.3	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2918593813	298	99.34	1	297	1	299	2.3e-50	166.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918593814	311	97.17	1	303	4	278	2.2e-40	133	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918593815	312	95.76	4	303	5	275	2.4e-41	136	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918593816	601	94.3	39	297	12	226	6.7e-60	196.1	COG0765	ABC-type amino acid transport system, permease component	222
2918593816	601	98.76	351	601	3	241	2.5e-105	345.1	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918593817	184	68.52	9	143	42	152	2.3e-10	35.2	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918593818	395	96.95	11	395	10	390	0.0e+00	439.8	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2918593819	446	97.96	11	414	6	341	1.2e-93	308.2	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918593820	333	98.83	11	332	4	342	1.7e-48	159.7	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918593821	149	90.67	1	147	2	137	5.9e-46	150.5	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918593823	181	87.57	10	181	9	170	3.6e-41	135.1	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918593824	389	97.96	13	361	1	336	2.4e-79	261.1	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918593826	393	68.25	10	220	25	168	2.3e-07	25.3	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
2918593827	309	96.17	20	302	8	283	3.4e-86	283.1	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2918593828	200	97.24	1	179	2	177	1.6e-65	214.4	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
2918593829	356	95.63	15	356	9	336	6.3e-68	223.6	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918593830	392	91.98	14	392	28	394	9.1e-50	164.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918593831	366	94.93	1	365	11	328	2.4e-78	258	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918593832	535	95.67	5	528	8	560	4.3e-115	379.9	COG0747	ABC-type transport system, periplasmic component	556
2918593833	329	97.48	5	329	6	315	3.0e-110	362.8	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918593834	331	91.28	36	329	24	295	5.4e-94	308.7	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918593835	332	98.77	4	318	1	321	2.8e-120	395.5	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918593836	311	97.5	1	304	3	314	4.0e-116	382.1	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918593837	351	97.5	2	320	2	313	1.4e-99	327.3	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918593838	412	96.74	6	406	9	394	2.7e-57	188.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918593839	323	98.34	24	321	2	297	2.8e-52	172.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918593840	450	99.71	13	420	1	342	3.3e-106	349.5	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918593841	531	98.1	1	530	7	573	2.5e-108	357.7	COG0747	ABC-type transport system, periplasmic component	556
2918593844	529	95.16	1	528	12	561	2.3e-112	371.1	COG0747	ABC-type transport system, periplasmic component	556
2918593845	399	98.98	12	399	3	391	2.6e-129	426	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2918593846	394	95.04	42	394	16	341	6.8e-85	279.4	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918593847	298	84.06	3	282	2	233	2.3e-54	179	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2918593848	355	90.15	1	350	23	324	1.5e-77	255.4	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918593849	435	96.5	17	418	12	342	8.3e-91	298.8	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918593850	342	87.46	9	329	10	309	3.6e-40	132.6	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918593851	348	99.39	4	329	3	326	4.8e-51	168.3	COG3547	Transposase	303
2918593852	143	80.83	1	114	9	105	3.3e-32	104.9	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2918593853	275	95.15	7	252	5	259	1.9e-57	189.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918593855	382	97.32	1	382	7	369	1.1e-87	288.6	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918593856	209	93.67	1	209	11	217	2.0e-31	104	COG2755	Lysophospholipase L1 or related esterase	216
2918593857	532	96.02	1	530	9	563	6.1e-99	326.7	COG0747	ABC-type transport system, periplasmic component	556
2918593858	252	97.65	2	252	3	251	4.3e-95	312.3	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
2918593859	278	85.85	5	277	1	279	5.3e-96	315.6	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918593860	295	90.94	3	294	25	295	2.5e-102	336.1	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918593861	340	96.86	7	340	8	315	8.7e-108	354.7	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918593862	211	96.63	1	208	5	205	1.6e-53	175.3	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918593863	243	96.27	4	242	6	237	1.8e-61	201.9	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918593864	328	97.54	3	325	7	323	2.1e-94	310.3	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918593865	275	98.31	1	275	3	292	3.5e-48	159	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918593866	263	98.49	1	258	4	264	2.2e-81	267.3	COG0300	Short-chain dehydrogenase	265
2918593868	431	91.54	133	404	12	249	2.9e-47	155.4	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918593868	431	100	1	131	1	130	3.3e-51	166.8	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
2918593869	118	93.22	14	118	2	111	3.3e-20	67	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918593870	135	68.72	1	135	18	162	2.5e-26	87.1	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
2918593871	145	69.67	2	145	18	164	9.4e-36	117.9	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
2918593872	505	99.41	2	505	3	508	0.0e+00	683.2	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
2918593873	423	99.31	2	423	3	433	0.0e+00	448.8	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2918593874	337	99.69	3	337	1	323	0.0e+00	489.5	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
2918593875	412	99.16	54	412	2	356	9.0e-123	403.8	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
2918593876	375	97.24	1	375	5	392	0.0e+00	464.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918593877	387	99.24	4	387	2	392	1.2e-122	404.1	COG0183	Acetyl-CoA acetyltransferase	392
2918593878	157	94.3	1	153	4	152	3.9e-35	115.6	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918593879	390	97.99	6	390	4	394	1.9e-130	429.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918593880	533	99.24	10	533	4	525	0.0e+00	686.8	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2918593881	663	99.85	1	660	1	645	0.0e+00	902.7	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918593882	303	70.46	5	302	2	292	1.2e-73	242.7	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918593883	256	98.49	1	254	5	265	9.2e-67	219.5	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918593884	292	98.95	1	282	1	282	6.3e-117	383.8	COG0414	Panthothenate synthetase	285
2918593885	279	98.51	8	274	3	266	8.9e-112	367	COG0413	Ketopantoate hydroxymethyltransferase	268
2918593886	430	100	2	430	1	430	0.0e+00	846.1	COG4952	L-rhamnose isomerase	430
2918593887	698	99.25	432	694	2	267	2.9e-60	198	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918593887	698	99.75	8	427	2	405	0.0e+00	539.4	COG3347	Rhamnose utilisation protein RhaD, predicted bifunctional aldolase and dehydrogenase	404
2918593888	276	99.61	1	256	1	253	5.2e-76	249.8	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2918593889	336	91.44	1	334	4	302	3.7e-71	234	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918593890	511	99.2	13	510	4	500	0.0e+00	639.8	COG1129	ABC-type sugar transport system, ATPase component	500
2918593891	333	96.87	1	317	7	315	2.3e-91	300.2	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918593892	336	96.87	21	335	7	315	5.8e-83	272.6	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918593893	107	99.05	4	107	2	105	2.0e-40	131.6	COG3254	L-rhamnose mutarotase	105
2918593894	460	88.05	9	456	6	447	1.8e-67	222.3	COG1070	Sugar (pentulose or hexulose) kinase	502
2918593895	278	97.97	1	278	5	293	5.8e-51	168.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918593897	640	70.59	160	638	174	641	0.0e+00	460.6	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918593898	168	100	1	168	1	155	8.1e-71	231.3	COG3915	Uncharacterized protein	155
2918593899	516	98.54	45	516	2	473	0.0e+00	540	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918593900	365	49.1	1	82	85	166	9.3e-108	88.4	COG4335	3-methyladenine DNA glycosylase AlkC	167
2918593900	365	100	96	262	1	167	9.3e-108	260.2	COG4335	3-methyladenine DNA glycosylase AlkC	167
2918593901	341	99.43	1	341	1	348	0.0e+00	431.9	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
2918593902	295	91.99	3	288	17	280	4.3e-129	423.8	COG4208	ABC-type sulfate transport system, permease component	287
2918593903	273	97.08	1	271	7	272	1.3e-108	356.4	COG0555	ABC-type sulfate transport system, permease component	274
2918593904	328	98.24	1	328	6	340	0.0e+00	570.1	COG4150	ABC-type sulfate transport system, periplasmic component	341
2918593905	356	98.87	5	326	4	265	6.4e-78	255.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918593907	281	93.08	1	147	11	158	5.8e-62	202.7	COG4991	Uncharacterized conserved protein YraI	155
2918593908	250	96.72	1	248	8	243	5.2e-99	324.7	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2918593909	142	99.3	1	142	2	142	3.8e-73	238.8	COG5319	Uncharacterized protein	142
2918593910	286	97.84	1	279	2	273	1.1e-73	242.1	COG0388	Predicted amidohydrolase	274
2918593911	84	98.75	2	79	2	80	2.7e-27	89.2	COG0695	Glutaredoxin	80
2918593912	263	99.11	26	259	2	223	5.3e-71	233.1	COG1040	Predicted amidophosphoribosyltransferases	225
2918593913	293	74.55	4	258	56	263	2.5e-07	25.5	COG0500	SAM-dependent methyltransferase	257
2918593914	64	89.66	7	64	3	54	1.4e-18	60.9	COG3847	Flp pilus assembly protein, pilin Flp	58
2918593916	137	78.49	1	136	14	148	3.8e-24	79.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918593917	258	43.92	92	256	82	164	2.5e-11	38.1	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918593918	413	99.01	5	413	5	405	0.0e+00	514.5	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
2918593919	287	87.69	4	277	34	318	2.1e-47	156.2	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918593920	905	99.76	4	896	3	840	0.0e+00	1264.4	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
2918593921	297	95.68	1	284	6	293	9.1e-40	131.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918593922	400	88.17	1	375	14	356	1.9e-16	54.1	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918593923	471	85.06	33	460	5	414	4.3e-74	244	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2918593926	264	95.93	9	263	10	292	2.3e-15	51.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918593927	157	60.82	1	155	104	266	2.8e-40	132.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918593928	196	44.02	15	191	11	102	8.6e-20	66.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918593940	158	80.81	2	145	18	156	9.8e-21	68.7	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918593944	384	95.81	88	383	6	302	1.6e-33	107.4	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918593945	435	97.74	1	426	10	442	3.5e-58	192.3	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918593946	296	96.98	3	295	5	293	3.8e-64	211.1	COG1175	ABC-type sugar transport system, permease component	295
2918593947	304	95.41	1	304	10	279	5.1e-63	207.5	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918593948	372	99.71	12	355	2	350	4.4e-129	425	COG3839	ABC-type sugar transport system, ATPase component	338
2918593950	300	93.44	1	267	7	248	7.3e-55	180.3	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2918593951	40	7.1	1	39	1	38	7.8e-12	38.8	COG1283	Na+/phosphate symporter	533
2918593952	817	93.8	1	816	54	870	0.0e+00	799.1	COG1643	HrpA-like RNA helicase	845
2918593953	435	81.47	10	431	69	389	2.3e-38	126.8	COG0642	Signal transduction histidine kinase	336
2918593954	195	97.25	16	195	6	182	4.4e-92	301.1	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918593955	161	96.34	1	161	1	158	2.7e-93	304.3	COG5321	Uncharacterized protein	164
2918593956	237	98.35	1	237	3	240	2.1e-68	225.4	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2918593957	722	99.31	3	720	5	576	0.0e+00	795.1	COG2225	Malate synthase	545
2918593959	435	100	1	435	1	444	0.0e+00	698.2	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
2918593960	174	97.75	1	174	4	177	3.0e-88	288.4	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
2918593961	198	99.49	1	197	2	195	5.1e-88	288.1	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
2918593963	216	99.02	1	216	2	203	1.4e-75	248	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
2918593964	247	98.76	1	242	2	239	1.7e-93	306.6	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
2918593965	258	99.22	2	258	2	256	2.8e-116	381.5	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
2918593966	107	97.92	6	103	1	94	2.0e-34	112.1	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
2918593967	322	100	11	297	1	282	5.6e-118	387.3	COG1072	Panthothenate kinase	283
2918593968	149	62.24	1	149	104	281	2.1e-23	76.4	COG1652	Nucleoid-associated protein YgaU, contains BON and LysM domains	269
2918593969	144	55.23	1	143	101	232	7.1e-35	114.9	COG1186	Protein chain release factor B	239
2918593970	536	98.11	6	532	9	527	0.0e+00	851	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
2918593971	248	98.71	9	248	2	230	6.8e-77	252.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918593972	596	90.86	197	596	35	392	2.0e-62	206.5	COG0642	Signal transduction histidine kinase	336
2918593973	154	48.38	1	154	129	277	8.0e-34	111.7	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
2918593974	133	89.51	1	132	1	128	2.4e-44	144.8	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
2918593975	91	97.75	3	90	3	89	2.3e-30	98.9	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
2918593976	466	99.52	3	458	3	419	0.0e+00	664.7	COG0499	S-adenosylhomocysteine hydrolase	420
2918593977	860	65.48	454	854	130	387	2.9e-63	209.2	COG0642	Signal transduction histidine kinase	336
2918593978	502	92.62	8	155	2	139	2.0e-41	135.2	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
2918593978	502	98.01	160	502	1	344	0.0e+00	465.3	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
2918593979	245	62.7	3	244	2	238	1.3e-48	160	COG1208	NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins	358
2918593980	1061	98.88	778	1058	1	266	1.2e-85	281.8	COG2887	RecB family exonuclease	269
2918593980	1061	100	8	765	1	698	0.0e+00	975.1	COG3893	Inactivated superfamily I helicase	697
2918593981	1185	99.57	13	1171	4	1150	0.0e+00	958.1	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2918593982	106	33.44	1	106	27	128	5.9e-33	109.2	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2918593983	447	97.9	3	447	5	424	0.0e+00	450	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
2918593984	298	92.52	1	292	17	288	9.3e-125	409.9	COG0777	Acetyl-CoA carboxylase beta subunit	294
2918593985	279	99.25	2	272	2	264	8.5e-101	330.6	COG0159	Tryptophan synthase alpha chain	265
2918593986	406	98.23	12	406	3	391	0.0e+00	678.1	COG0133	Tryptophan synthase beta chain	396
2918593987	220	98.56	2	213	2	207	3.9e-64	210.7	COG0135	Phosphoribosylanthranilate isomerase	208
2918593988	255	98.68	22	252	3	226	1.6e-74	244.7	COG1451	Predicted metal-dependent hydrolase	223
2918593989	410	98.55	1	410	1	409	0.0e+00	753.9	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
2918593990	280	98.17	10	279	3	270	1.3e-91	301.2	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918593991	200	86.57	12	192	8	194	7.3e-20	64.1	COG0778	Nitroreductase	207
2918593992	811	99.69	10	811	3	641	0.0e+00	968.8	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
2918593993	121	83.08	3	119	2	109	1.1e-19	65.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918593994	190	99.46	2	188	1	183	9.7e-52	170.1	COG2840	DNA-nicking endonuclease, Smr domain	184
2918593995	369	98.42	1	369	7	379	1.1e-121	401	COG2821	Membrane-bound lytic murein transglycosylase	373
2918593996	224	81.85	1	224	52	281	1.4e-76	252.3	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
2918593997	182	98.76	2	178	2	160	1.5e-54	178.1	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
2918593998	160	92.99	1	159	5	150	1.7e-63	207.2	COG1952	Preprotein translocase subunit SecB	157
2918593999	232	87.8	1	229	17	239	1.1e-60	200.1	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2918594000	202	97.51	1	197	2	197	1.9e-55	182	COG0237	Dephospho-CoA kinase	201
2918594001	286	96.83	4	284	7	281	7.2e-90	295.1	COG0169	Shikimate 5-dehydrogenase	283
2918594002	199	97.94	1	199	1	190	5.5e-57	186.5	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
2918594003	252	91.21	1	252	20	268	4.7e-98	322.4	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
2918594004	344	97.17	1	343	7	349	1.6e-119	393.4	COG0407	Uroporphyrinogen-III decarboxylase	352
2918594005	181	97.99	35	180	4	149	2.7e-65	213.4	COG1981	Uncharacterized membrane protein	149
2918594006	421	99.05	1	421	2	419	0.0e+00	733.1	COG1158	Transcription termination factor Rho	422
2918594007	442	99.56	2	442	3	454	0.0e+00	478.7	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
2918594008	627	99.52	1	619	1	621	0.0e+00	887.6	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
2918594009	205	90.23	1	202	14	207	1.6e-57	188.7	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
2918594010	264	97.73	5	262	2	259	1.1e-84	278.6	COG1192	Cellulose biosynthesis protein BcsQ	259
2918594011	293	98.86	34	286	3	263	6.9e-79	259.8	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918594012	69	77.38	1	69	20	84	2.8e-23	77.1	COG5508	Uncharacterized protein	84
2918594013	321	96.79	1	283	8	309	9.5e-84	275.6	COG0501	Zn-dependent protease with chaperone function	302
2918594014	461	99.72	129	461	1	357	1.4e-91	301.7	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
2918594015	563	99.47	1	563	2	564	0.0e+00	933	COG5360	Uncharacterized conserved protein, heparinase superfamily	566
2918594016	538	99.81	15	538	2	515	0.0e+00	751.4	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
2918594017	510	12.56	6	101	177	226	0.0e+00	12.6	COG2721	Altronate dehydratase	381
2918594017	510	99.75	105	510	2	398	0.0e+00	578.6	COG2721	Altronate dehydratase	381
2918594018	230	95.44	3	230	4	233	3.2e-62	204.4	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918594019	521	99.2	18	516	4	500	0.0e+00	674.5	COG1129	ABC-type sugar transport system, ATPase component	500
2918594020	340	96.87	14	340	6	314	1.1e-102	337.5	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918594021	313	97.86	1	313	5	324	1.9e-78	258	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918594022	337	95.94	4	333	2	308	8.1e-68	222.9	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918594023	273	97.14	1	271	8	279	3.2e-86	283.7	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2918594024	336	99.43	1	335	2	352	2.1e-87	287.4	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918594025	377	80.38	1	377	15	395	8.2e-83	273.1	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
2918594026	109	100	1	109	1	105	4.2e-45	146.7	COG3254	L-rhamnose mutarotase	105
2918594027	425	98.93	2	425	2	370	1.0e-86	283.7	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918594028	348	97.78	8	346	3	355	8.9e-71	232.8	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2918594029	321	97.5	1	321	6	317	6.9e-108	354.7	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
2918594030	485	99.18	3	485	3	484	0.0e+00	611.8	COG1492	Cobyric acid synthase	486
2918594031	205	99.49	8	205	2	198	1.6e-80	263.9	COG2109	ATP:corrinoid adenosyltransferase	198
2918594033	128	92.31	1	127	11	142	1.6e-44	145.7	COG5469	Predicted metal-binding protein	143
2918594034	345	98.77	8	345	1	322	1.3e-96	318.2	COG0523	GTPase, G3E family	323
2918594035	1116	30.49	685	1110	834	1266	0.0e+00	448.8	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
2918594035	1116	50.85	4	693	10	731	0.0e+00	591.6	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
2918594036	451	38.13	1	204	23	218	1.7e-68	97.4	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2918594036	451	42.8	217	450	290	509	1.7e-68	126.6	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2918594037	210	97.16	1	210	1	205	4.0e-80	262.7	COG2082	Precorrin isomerase	210
2918594038	255	99.15	10	249	2	234	7.2e-82	268.7	COG2243	Precorrin-2 methylase	234
2918594039	253	98.4	1	253	1	246	1.2e-94	310.8	COG1010	Precorrin-3B methylase	249
2918594040	260	99.22	1	254	2	256	9.7e-81	265.3	COG2099	Precorrin-6x reductase	257
2918594041	419	98.93	235	418	2	186	1.6e-71	229.5	COG2242	Precorrin-6B methylase 2	187
2918594041	419	99.05	20	227	1	208	6.3e-66	215.7	COG2241	Precorrin-6B methylase 1	210
2918594042	139	41.82	1	138	50	182	8.5e-17	54.9	COG2073	Cobalamin biosynthesis protein CbiG	298
2918594043	257	98.43	1	253	3	253	8.4e-108	353.5	COG2875	Precorrin-4 methylase	254
2918594044	376	98.09	1	362	4	363	2.2e-128	422.5	COG1903	Cobalamin biosynthesis protein CbiD	367
2918594045	262	97.54	17	261	3	240	1.0e-85	281.6	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2918594046	438	96.47	4	438	2	438	0.0e+00	516.4	COG1797	Cobyrinic acid a,c-diamide synthase	451
2918594047	414	84.93	1	391	56	365	1.6e-106	350.4	COG1858	Cytochrome c peroxidase	364
2918594048	370	98.28	1	368	5	346	9.7e-127	417	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2918594049	201	97.41	1	200	1	188	1.1e-81	267.5	COG0066	3-isopropylmalate dehydratase small subunit	191
2918594051	303	99.65	15	300	1	284	1.4e-98	323.9	COG2301	Citrate lyase beta subunit	283
2918594052	68	95.71	1	68	4	70	3.9e-38	123.8	COG5515	Uncharacterized protein	70
2918594053	146	99.26	5	140	1	135	3.3e-65	212.3	COG3824	Predicted Zn-dependent protease, minimal metalloprotease (MMP)-like domain	136
2918594054	104	99.03	1	103	1	102	8.0e-43	139.5	COG0261	Ribosomal protein L21	103
2918594055	89	98.85	1	87	1	86	9.1e-44	141.7	COG0211	Ribosomal protein L27	87
2918594056	210	98.93	24	204	1	185	6.9e-43	141.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918594057	196	97.86	18	195	3	185	5.9e-34	112.1	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918594058	356	92.29	1	355	1	335	0.0e+00	448.6	COG0536	GTPase involved in cell partioning and DNA repair	369
2918594059	389	99.19	6	373	3	369	0.0e+00	470.7	COG0263	Glutamate 5-kinase	369
2918594060	428	98.8	12	428	5	416	0.0e+00	577	COG0014	Gamma-glutamyl phosphate reductase	417
2918594061	207	96.98	19	207	3	195	4.0e-51	168	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
2918594062	158	93.04	44	158	5	111	5.7e-43	139.6	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
2918594063	160	100	1	159	1	156	1.2e-54	179	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
2918594064	465	97.18	6	455	12	425	0.0e+00	462.1	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
2918594065	442	96.57	4	417	6	399	0.0e+00	445.1	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
2918594066	373	96.86	121	373	3	249	9.0e-92	300.9	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
2918594067	170	88.95	3	169	11	163	9.8e-25	81.6	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918594068	161	98.09	1	157	2	155	2.1e-70	229.9	COG2193	Bacterioferritin (cytochrome b1)	157
2918594071	241	98.51	1	239	4	267	1.3e-75	248.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918594072	393	98.98	4	393	4	393	0.0e+00	483	COG0183	Acetyl-CoA acetyltransferase	392
2918594073	191	98.96	1	191	3	193	5.8e-102	334.1	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
2918594074	458	96.03	3	458	9	443	0.0e+00	517.7	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
2918594075	1586	99.94	1	1586	1	1592	0.0e+00	2176.1	COG2902	NAD-specific glutamate dehydrogenase	1592
2918594076	189	98.19	10	174	2	164	6.5e-69	225.3	COG1329	RNA polymerase-interacting regulator, CarD/CdnL/TRCF family	166
2918594077	182	80.65	1	182	42	216	7.4e-72	235.9	COG3786	L,D-peptidoglycan transpeptidase YkuD, ErfK/YbiS/YcfS/YnhG family	217
2918594078	227	98.28	4	227	2	229	7.3e-65	212.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918594079	161	63.3	19	161	2	139	4.3e-23	76.3	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918594080	267	99.23	3	267	2	258	2.5e-74	244.1	COG0708	Exonuclease III	261
2918594081	224	93.9	22	223	7	206	1.0e-48	160	COG2834	Outer membrane lipoprotein-sorting protein	211
2918594082	888	96.24	27	886	32	928	0.0e+00	837.7	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2918594083	448	98.3	40	448	2	406	0.0e+00	516.4	COG0004	Ammonia channel protein AmtB	409
2918594084	112	100	1	112	1	112	1.2e-48	158.5	COG0347	Nitrogen regulatory protein PII	112
2918594085	294	98.62	7	294	2	287	2.5e-129	424.8	COG1946	Acyl-CoA thioesterase	289
2918594086	404	98.98	1	392	3	391	6.3e-111	365.8	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918594088	1031	99.04	47	826	2	516	1.5e-50	165.9	COG0513	Superfamily II DNA and RNA helicase	513
2918594089	138	94	1	106	5	98	1.1e-30	100.1	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
2918594090	112	89.04	1	65	5	69	2.4e-19	63.3	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2918594091	345	98.8	4	343	2	331	1.1e-77	255.8	COG1466	DNA polymerase III, delta subunit	334
2918594092	181	99.42	4	181	1	171	4.2e-76	249	COG5468	Predicted secreted (periplasmic) protein	172
2918594093	876	99.76	2	876	3	823	0.0e+00	1056.7	COG0495	Leucyl-tRNA synthetase	814
2918594094	219	99.13	1	219	1	227	1.2e-74	245.1	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
2918594095	233	100	1	231	1	230	9.5e-129	422.1	COG3820	Uncharacterized protein	230
2918594096	650	100	66	631	1	552	0.0e+00	810.9	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918594097	335	99.4	1	331	1	330	4.1e-113	372.3	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918594098	425	99.21	47	425	1	376	0.0e+00	475	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918594099	176	96.61	1	173	5	175	4.1e-57	186.7	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918594100	386	100	7	386	1	379	0.0e+00	647.9	COG3970	Fumarylacetoacetate (FAA) hydrolase family protein	379
2918594101	238	93.78	6	236	7	232	1.3e-62	205.4	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918594102	481	99.57	12	478	2	468	3.5e-110	363.2	COG0277	FAD/FMN-containing dehydrogenase	459
2918594103	328	97.51	1	325	2	314	1.4e-46	153.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918594104	300	99.3	10	292	2	285	4.6e-98	322.2	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918594105	594	98.27	1	580	7	574	0.0e+00	611.2	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918594106	324	92.2	1	323	8	326	3.1e-108	356.2	COG1171	Threonine dehydratase	347
2918594107	367	86.51	1	367	1	372	4.5e-102	336.1	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
2918594109	392	97.46	3	392	9	391	0.0e+00	462.5	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2918594110	2831	15.62	1522	1713	284	448	0.0e+00	30.5	COG3459	Cellobiose phosphorylase	1056
2918594110	2831	97.73	1746	2829	1	1032	0.0e+00	1531	COG3459	Cellobiose phosphorylase	1056
2918594111	81	14.79	1	77	277	330	4.8e-04	13.8	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
2918594112	588	99.32	4	573	3	590	0.0e+00	476.4	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918594113	245	78.75	175	244	17	79	2.5e-20	65.6	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918594114	1153	99.48	1	1153	6	1148	0.0e+00	1950.9	COG1038	Pyruvate carboxylase	1149
2918594115	266	98.03	4	255	4	252	1.1e-64	212.7	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2918594116	396	38.48	21	201	241	392	1.4e-17	45.6	COG2814	Predicted arabinose efflux permease, MFS family	394
2918594116	396	55.95	173	396	170	390	1.4e-17	25.9	COG2814	Predicted arabinose efflux permease, MFS family	394
2918594117	416	98.65	10	415	2	366	0.0e+00	457.5	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
2918594118	220	95.48	21	218	9	198	1.8e-55	182.5	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918594119	300	90.24	2	300	2	297	1.4e-81	267.9	COG0142	Geranylgeranyl pyrophosphate synthase	322
2918594120	248	31.84	9	245	31	257	2.8e-64	212	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2918594121	339	99.04	8	339	2	311	5.8e-92	302.6	COG2017	Galactose mutarotase or related enzyme	308
2918594122	308	98.37	1	306	1	302	0.0e+00	494.7	COG1897	Homoserine trans-succinylase	307
2918594124	217	99.07	3	214	2	213	1.6e-59	194.8	COG1564	Thiamine pyrophosphokinase	212
2918594125	608	16.45	3	100	3	90	0.0e+00	78.5	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918594125	608	20	478	598	228	334	0.0e+00	10.2	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918594125	608	70.65	93	480	134	511	0.0e+00	411.9	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918594126	130	96.99	1	130	2	130	2.5e-60	196.6	COG3607	Predicted lactoylglutathione lyase	133
2918594128	337	99.41	1	336	2	337	0.0e+00	470.9	COG4143	ABC-type thiamine transport system, periplasmic component	336
2918594129	541	96.32	1	539	8	531	3.9e-124	409.2	COG1178	ABC-type Fe3+ transport system, permease component	540
2918594130	238	99.13	7	237	2	230	1.0e-104	343.3	COG3840	ABC-type thiamine transport system, ATPase component	231
2918594131	504	99.58	25	504	3	479	0.0e+00	867.7	COG4784	Putative Zn-dependent protease	479
2918594132	209	95.22	8	207	5	203	1.1e-19	66.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918594133	168	95.35	1	164	5	168	9.7e-19	62.2	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
2918594134	469	99.3	2	469	3	428	0.0e+00	657.1	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
2918594135	425	92	4	425	26	439	5.9e-28	92	COG2271	Sugar phosphate permease	448
2918594136	320	47.68	4	318	227	493	2.2e-06	19.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918594137	429	96.67	1	420	13	389	1.7e-48	160.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918594138	553	92.93	1	548	35	573	0.0e+00	783.6	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2918594139	179	95.08	1	119	6	121	2.3e-51	166.9	COG0335	Ribosomal protein L19	115
2918594140	248	97.68	1	248	2	254	1.1e-43	143.7	COG0730	Uncharacterized membrane protein YfcA	258
2918594141	232	93.85	3	232	2	230	8.3e-97	317.2	COG0336	tRNA G37 N-methylase TrmD	240
2918594142	188	98.28	1	171	1	171	3.0e-51	167.6	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
2918594143	125	93.33	2	115	1	84	1.0e-34	112.4	COG0228	Ribosomal protein S16	87
2918594144	105	93.07	1	100	3	96	4.1e-28	92	COG1605	Chorismate mutase	101
2918594145	522	98.45	1	456	1	445	0.0e+00	597	COG0541	Signal recognition particle GTPase	451
2918594147	356	96.6	87	356	2	257	2.4e-70	231	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
2918594148	300	98.89	5	284	2	269	7.3e-89	292	COG0253	Diaminopimelate epimerase	272
2918594149	424	99.09	1	421	3	439	1.5e-129	427	COG0621	tRNA A37 methylthiotransferase MiaB	437
2918594150	478	90.56	101	477	33	358	1.5e-120	396.7	COG0552	Signal recognition particle GTPase	340
2918594151	216	97.22	21	214	1	175	9.1e-67	219	COG2917	Intracellular septation protein A	180
2918594153	393	93.99	188	376	10	181	1.8e-46	152.3	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918594154	200	96	43	177	5	148	6.4e-15	49.8	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2918594155	57	64.18	1	57	15	57	2.0e-04	16	COG3114	Heme exporter protein D	67
2918594156	253	81.91	2	248	40	270	1.4e-74	245.2	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
2918594157	219	98.64	1	219	4	221	7.8e-85	278.2	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
2918594159	213	98.09	1	211	1	205	2.1e-80	263.6	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
2918594160	897	99.66	6	897	2	868	0.0e+00	1328.5	COG1048	Aconitase A	861
2918594161	246	91.95	2	246	20	259	4.0e-111	364.6	COG5429	Uncharacterized protein	261
2918594164	245	97.41	1	245	6	231	3.0e-86	282.9	COG0670	Integral membrane protein, interacts with FtsH	233
2918594166	853	99.4	8	851	5	828	0.0e+00	1118	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
2918594167	236	98.25	1	225	4	227	1.2e-107	352.8	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
2918594168	216	93.21	16	211	12	217	5.7e-40	131.8	COG2755	Lysophospholipase L1 or related esterase	216
2918594169	197	99.45	2	178	1	181	4.6e-53	174	COG1514	2'-5' RNA ligase	180
2918594170	159	97.97	2	154	3	147	5.3e-47	153.9	COG0394	Protein-tyrosine-phosphatase	139
2918594171	101	93.07	1	100	3	96	1.3e-32	106.1	COG2154	Pterin-4a-carbinolamine dehydratase	101
2918594172	126	94.83	13	126	5	114	3.9e-39	127.6	COG3339	Uncharacterized membrane protein YkvA, DUF1232 family	116
2918594173	167	88.4	1	167	20	179	8.4e-06	17.9	COG5342	Invasion protein IalB, involved in pathogenesis	181
2918594174	412	99.43	26	395	1	347	0.0e+00	495.7	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
2918594175	317	97.2	1	317	9	321	3.0e-130	428.2	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
2918594176	293	96.93	1	293	2	285	1.2e-125	413.1	COG4120	ABC-type uncharacterized transport system, permease component	293
2918594177	264	99.62	1	263	2	263	1.9e-123	405.1	COG1101	ABC-type uncharacterized transport system, ATPase component	263
2918594178	215	99.04	5	214	2	207	1.2e-60	198.5	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918594179	284	82.84	9	272	5	226	3.4e-44	145.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918594180	407	98.76	4	407	3	400	0.0e+00	583.5	COG0137	Argininosuccinate synthase	403
2918594181	392	85.32	3	391	30	366	2.1e-21	70	COG2814	Predicted arabinose efflux permease, MFS family	394
2918594182	143	96.24	4	136	5	132	7.7e-25	81.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918594183	686	98.83	4	686	7	681	0.0e+00	890.4	COG0339	Zn-dependent oligopeptidase	683
2918594184	606	99.34	1	603	4	602	0.0e+00	976.1	COG1217	Predicted membrane GTPase involved in stress response	603
2918594185	168	76.72	3	155	20	164	1.1e-10	35.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918594186	177	98.84	1	175	2	171	3.0e-72	236.3	COG0221	Inorganic pyrophosphatase	171
2918594187	103	95.1	1	103	4	100	1.6e-32	105.8	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
2918594188	96	96.88	4	96	2	94	4.0e-25	82.4	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
2918594189	410	28.98	279	407	76	186	3.0e-18	14.3	COG0477	MFS family permease	338
2918594189	410	70.5	11	283	8	277	3.0e-18	52.4	COG0477	MFS family permease	338
2918594190	243	95.96	13	209	4	193	4.1e-48	157.9	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2918594191	162	98.65	1	146	3	148	1.6e-65	213.9	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
2918594192	538	100	1	538	1	531	0.0e+00	852.4	COG3898	Uncharacterized membrane-anchored protein	531
2918594193	483	8.06	1	40	3	36	0.0e+00	1.1	COG4223	Uncharacterized conserved protein	422
2918594193	483	99.53	29	478	2	421	0.0e+00	519.7	COG4223	Uncharacterized conserved protein	422
2918594194	246	96.8	1	243	2	243	9.0e-49	160	COG1587	Uroporphyrinogen-III synthase	248
2918594195	309	98.7	3	309	2	304	5.8e-111	364.7	COG0181	Porphobilinogen deaminase	307
2918594196	365	97.97	5	355	2	338	0.0e+00	444.8	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
2918594197	327	99.7	3	327	2	329	1.1e-107	354.4	COG0240	Glycerol-3-phosphate dehydrogenase	329
2918594198	97	100	1	92	1	92	2.6e-36	118.3	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
2918594199	147	99.36	1	143	1	155	2.1e-59	193	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
2918594200	214	97.72	1	214	6	219	4.9e-96	314.5	COG3897	Predicted nicotinamide N-methyase	218
2918594202	130	96.99	6	130	2	130	5.5e-38	124.6	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
2918594203	126	98.29	7	123	2	116	1.9e-37	122	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
2918594204	613	99.29	14	595	4	565	0.0e+00	768.7	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918594205	259	97.45	26	259	4	232	9.0e-94	307.2	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
2918594207	387	96.77	4	384	10	369	0.0e+00	471.7	COG1485	Predicted ATPase	367
2918594208	320	98.41	4	317	1	310	2.1e-115	379.3	COG0039	Malate/lactate dehydrogenase	313
2918594209	397	99.48	1	397	1	381	0.0e+00	503.4	COG0045	Succinyl-CoA synthetase, beta subunit	387
2918594210	300	98.98	1	300	1	291	1.6e-127	419.1	COG0074	Succinyl-CoA synthetase, alpha subunit	293
2918594211	998	99.78	7	998	2	922	0.0e+00	1446.4	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
2918594212	407	99.77	1	406	1	433	0.0e+00	516.7	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2918594213	136	97.6	12	136	3	124	1.0e-37	123.1	COG3686	Uncharacterized conserved protein, MAPEG superfamily	125
2918594214	213	98.56	3	212	3	207	2.7e-58	190.9	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918594215	468	99.34	1	458	4	455	0.0e+00	566.6	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918594216	166	22.65	120	166	138	178	5.3e-43	37.6	COG3038	Cytochrome b561	181
2918594216	166	61.33	2	128	3	113	5.3e-43	108.8	COG3038	Cytochrome b561	181
2918594218	365	99.33	58	365	3	299	2.5e-116	382.1	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
2918594219	311	95.65	9	311	11	296	2.0e-73	241.6	COG4973	Site-specific recombinase XerC	299
2918594220	738	99.86	19	737	2	734	0.0e+00	854.8	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
2918594222	186	98.31	5	183	4	178	1.6e-59	195.1	COG0712	FoF1-type ATP synthase, delta subunit	178
2918594223	509	99.21	1	509	1	500	0.0e+00	807.6	COG0056	FoF1-type ATP synthase, alpha subunit	504
2918594224	292	99.65	5	292	1	287	7.0e-105	345.1	COG0224	FoF1-type ATP synthase, gamma subunit	287
2918594225	484	99.36	14	482	3	467	0.0e+00	799.2	COG0055	FoF1-type ATP synthase, beta subunit	468
2918594226	136	97.04	1	134	1	131	4.1e-39	127.7	COG0355	FoF1-type ATP synthase, epsilon subunit	135
2918594227	268	94.01	2	268	16	266	1.9e-92	303.5	COG1526	Formate dehydrogenase assembly factor FdhD	266
2918594228	553	81.88	29	507	78	425	6.5e-113	372.5	COG0840	Methyl-accepting chemotaxis protein	408
2918594229	158	91.52	1	158	11	161	1.3e-50	165.5	COG0835	Chemotaxis signal transduction protein	165
2918594230	1386	99.63	2	1386	6	1334	0.0e+00	1383.8	COG2911	Autotransporter translocation and assembly factor TamB	1278
2918594231	617	99.67	8	617	3	603	0.0e+00	616.5	COG0729	Outer membrane translocation and assembly module TamA	594
2918594232	83	24.02	10	83	72	114	5.4e-05	17.7	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
2918594233	405	100	1	395	1	390	0.0e+00	489.2	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
2918594234	397	99.22	8	395	2	384	0.0e+00	517.8	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
2918594235	233	90.09	16	225	23	231	5.3e-33	109.6	COG0671	Membrane-associated phospholipid phosphatase	232
2918594236	417	89.06	18	407	2	351	2.0e-73	242.3	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918594237	308	96.77	1	305	7	306	4.9e-59	194.2	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918594238	389	99.21	3	383	2	379	3.3e-128	421.9	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
2918594239	340	100	1	339	1	340	2.0e-107	353.5	COG2222	Fructoselysine-6-P-deglycase FrlB and related proteins with duplicated sugar isomerase (SIS) domain	340
2918594240	250	97.91	7	245	5	238	1.1e-73	241.9	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918594241	393	96.3	1	371	4	341	3.5e-56	184.5	COG0673	Predicted dehydrogenase	342
2918594242	294	97.65	1	293	6	296	9.8e-86	282.1	COG1175	ABC-type sugar transport system, permease component	295
2918594243	285	96.82	4	285	10	283	5.1e-83	272.9	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918594244	410	95.26	2	410	17	438	3.2e-69	228.7	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918594245	370	99.14	2	353	3	349	0.0e+00	457.8	COG3839	ABC-type sugar transport system, ATPase component	338
2918594247	287	98.94	1	278	3	281	5.9e-76	249.5	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918594248	260	98.51	2	246	4	267	7.6e-57	187.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918594249	639	86.75	4	639	1	635	0.0e+00	864.7	COG3525	N-acetyl-beta-hexosaminidase	732
2918594250	477	99.6	1	470	1	493	0.0e+00	589.3	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
2918594251	401	45.95	219	399	15	190	2.8e-09	13.3	COG0477	MFS family permease	338
2918594251	401	54.05	6	239	8	214	2.8e-09	23.1	COG0477	MFS family permease	338
2918594252	246	98.76	1	238	2	239	1.6e-90	296.9	COG3142	Copper homeostasis protein CutC	241
2918594253	383	96.5	1	383	6	391	0.0e+00	458.1	COG4671	Predicted glycosyl transferase	400
2918594254	415	88.02	7	410	44	403	3.5e-37	123.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918594255	402	97.25	1	400	6	394	0.0e+00	560.6	COG4671	Predicted glycosyl transferase	400
2918594256	391	96.31	28	391	7	293	1.7e-85	280.7	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918594257	332	99.37	1	328	1	316	6.3e-90	296.1	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918594258	633	96.19	1	620	7	562	1.3e-79	262.8	COG0747	ABC-type transport system, periplasmic component	556
2918594259	630	98.91	1	575	5	550	0.0e+00	697.7	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918594260	320	76.86	17	312	2	270	1.9e-56	186.1	COG3774	Mannosyltransferase OCH1 or related enzyme	347
2918594262	365	77.02	6	362	88	402	2.4e-32	107.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918594263	446	99.31	10	446	3	435	0.0e+00	573.6	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
2918594265	555	23.93	103	180	50	77	1.7e-03	7.4	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
2918594265	555	73.5	3	105	22	107	1.7e-03	8.5	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
2918594265	555	93.44	314	555	8	235	2.0e-51	168.7	COG2114	Adenylate cyclase, class 3	227
2918594266	286	98.53	11	286	3	271	1.7e-65	215.3	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2918594267	143	63.76	1	142	2	140	1.7e-27	90.6	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918594268	905	39.86	491	905	352	587	1.2e-72	82.1	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918594268	905	76.18	1	491	6	456	1.2e-72	156.1	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918594269	601	26.69	313	464	44	118	1.7e-06	5.8	COG4757	Predicted alpha/beta hydrolase	281
2918594269	601	41.28	28	205	42	157	1.7e-06	17.8	COG4757	Predicted alpha/beta hydrolase	281
2918594270	818	99.05	1	817	8	838	0.0e+00	512.7	COG3250	Beta-galactosidase/beta-glucuronidase	808
2918594272	302	74.48	1	302	98	418	3.2e-43	142.3	COG0172	Seryl-tRNA synthetase	429
2918594273	393	91.48	5	388	22	386	2.1e-39	129.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918594274	83	88.89	1	81	6	77	1.3e-14	48.5	COG0236	Acyl carrier protein	80
2918594277	607	99.31	125	579	2	432	0.0e+00	740.6	COG0422	Thiamine biosynthesis protein ThiC	432
2918594278	334	93.04	1	326	5	365	2.4e-48	159	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918594279	65	97.06	1	65	3	68	1.7e-20	67.4	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
2918594280	257	96.95	1	257	7	260	1.6e-112	369.3	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
2918594281	334	92.24	1	331	11	331	4.6e-101	332.5	COG3191	L-aminopeptidase/D-esterase	348
2918594282	131	90.84	7	131	4	122	8.8e-45	146.2	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
2918594283	358	99.43	2	357	2	351	0.0e+00	501.9	COG4148	ABC-type molybdate transport system, ATPase component	352
2918594284	235	98.67	8	233	2	223	1.3e-93	306.7	COG4149	ABC-type molybdate transport system, permease component	225
2918594285	263	95.88	1	263	11	266	1.7e-73	241.5	COG0725	ABC-type molybdate transport system, periplasmic component	258
2918594286	427	97.16	27	408	5	381	3.2e-67	221.6	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918594287	308	97.67	10	298	2	295	8.0e-63	207.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918594288	78	47.47	1	77	71	145	4.9e-11	37.3	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918594290	354	93.24	1	353	22	366	0.0e+00	460.8	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
2918594291	354	99.07	6	352	3	321	0.0e+00	450.8	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
2918594292	189	100	1	131	1	131	8.7e-43	139.4	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
2918594293	483	97.83	12	468	1	450	1.4e-115	381	COG1538	Outer membrane protein TolC	457
2918594294	1029	99.8	1	1026	2	1013	0.0e+00	1175.5	COG0841	Multidrug efflux pump subunit AcrB	1009
2918594295	400	94.62	1	392	9	377	1.1e-65	216.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918594296	219	95.22	15	219	5	203	1.6e-27	91.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918594297	316	98.55	6	289	5	275	4.9e-90	295.6	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
2918594298	296	89.43	1	292	37	349	3.1e-125	412.1	COG3839	ABC-type sugar transport system, ATPase component	338
2918594299	258	99.25	3	257	2	267	3.5e-66	217.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918594300	494	99.37	14	486	3	473	0.0e+00	547.7	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
2918594301	239	96.38	6	224	4	216	6.2e-57	187	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2918594302	524	97.25	1	524	1	530	0.0e+00	669.5	COG1069	Ribulose kinase	544
2918594303	271	96.45	1	271	10	281	1.0e-40	133.9	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918594304	245	98.4	1	237	3	248	1.5e-80	264.7	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
2918594305	248	98.1	19	229	3	209	2.6e-87	285.7	COG0177	Endonuclease III	211
2918594306	160	95.12	1	158	9	164	7.4e-77	250.9	COG5488	Uncharacterized membrane protein	164
2918594307	290	83.33	2	134	16	125	8.9e-18	58.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918594307	290	98.81	125	288	2	167	3.2e-46	151.7	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2918594308	93	92.77	14	93	3	79	9.2e-26	84.1	COG3905	Predicted transcriptional regulator	83
2918594309	95	92.93	1	95	4	95	5.8e-22	72.6	COG3668	Plasmid stabilization system protein ParE	98
2918594310	328	98.75	9	328	3	318	4.3e-114	375.1	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
2918594311	321	99.01	5	314	2	302	2.1e-106	350.2	COG0176	Transaldolase	239
2918594312	257	97.97	12	252	2	242	3.0e-61	200.7	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918594313	243	99.25	3	243	2	267	2.9e-61	201.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918594314	57	98.15	1	54	1	53	6.3e-25	81.5	COG5487	Uncharacterized membrane protein YtjA, UPF0391 family	54
2918594315	284	97.83	4	275	3	272	3.6e-87	286.4	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2918594316	286	99.28	1	273	2	275	1.2e-87	288.1	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2918594317	302	95.67	10	262	5	247	1.2e-92	304	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
2918594318	296	91.8	4	296	25	304	5.1e-98	322.1	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
2918594320	579	9.4	23	97	35	64	7.9e-10	14.5	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2918594320	579	17.55	293	459	153	208	7.9e-10	16.4	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2918594321	499	98.43	1	498	8	508	0.0e+00	656.7	COG1190	Lysyl-tRNA synthetase (class II)	502
2918594322	485	98.33	1	476	7	478	0.0e+00	469.8	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2918594323	590	99.38	15	590	1	480	1.3e-118	390.8	COG0471	Di- and tricarboxylate transporter	461
2918594324	253	96.48	1	249	7	253	1.1e-87	287.8	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918594325	228	82.3	17	223	11	182	1.8e-27	91.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918594326	404	97.73	32	400	7	350	1.3e-119	393.4	COG1566	Multidrug resistance efflux pump	352
2918594327	527	42.3	274	520	4	165	1.4e-37	18.5	COG0477	MFS family permease	338
2918594327	527	71.54	21	278	3	276	1.4e-37	110	COG0477	MFS family permease	338
2918594328	216	98.28	9	181	3	173	4.0e-41	135	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2918594329	340	96.33	6	340	3	317	9.2e-42	137.3	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918594330	488	98.8	1	488	2	497	0.0e+00	528.7	COG1070	Sugar (pentulose or hexulose) kinase	502
2918594331	436	100	1	436	1	438	0.0e+00	808.2	COG2115	Xylose isomerase	438
2918594333	459	97.62	8	451	3	454	0.0e+00	501	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2918594334	209	95.83	1	209	6	212	1.2e-36	120.9	COG0778	Nitroreductase	207
2918594335	371	99.71	26	369	1	339	0.0e+00	447.2	COG1135	ABC-type methionine transport system, ATPase component	339
2918594336	222	96.85	1	218	8	222	2.1e-91	299.6	COG2011	ABC-type methionine transport system, permease component	222
2918594337	259	98.15	1	259	6	270	2.9e-113	371.7	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
2918594338	715	43.05	1	222	15	141	2.8e-10	33.6	COG3322	Extracellular (periplasmic) sensor domain CHASE (specificity unknown)	295
2918594338	715	94.54	264	445	9	181	4.5e-47	153.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918594338	715	97.67	456	707	2	252	1.2e-86	283.9	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918594339	314	96.75	12	314	4	301	6.0e-127	417.3	COG1054	Predicted sulfurtransferase	308
2918594340	302	72.44	28	272	34	238	2.5e-08	27.6	COG5607	CHAD domain (function unknown)	283
2918594341	162	96.15	1	158	1	150	2.3e-72	236.3	COG2954	CYTH domain, found in class IV adenylate cyclase and various triphosphatases	156
2918594342	212	97.63	3	212	3	208	1.7e-79	260.4	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
2918594343	231	99.11	2	231	1	223	9.8e-97	317	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
2918594344	228	96.26	10	196	6	185	2.4e-29	96.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918594345	76	38.3	14	76	21	74	1.8e-03	12.8	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
2918594346	349	99.36	19	349	2	312	4.5e-111	365.2	COG2215	ABC-type nickel/cobalt efflux system, permease component RcnA	303
2918594347	213	97.69	1	213	6	216	4.0e-82	269.4	COG3683	ABC-type uncharacterized transport system, periplasmic component	213
2918594350	215	99.58	2	215	2	236	1.3e-33	111.1	COG3637	Opacity protein and related surface antigens	199
2918594352	393	49.35	210	392	5	193	1.5e-02	5.7	COG0477	MFS family permease	338
2918594352	393	49.61	8	207	6	195	1.5e-02	9.8	COG0477	MFS family permease	338
2918594353	330	45.58	14	330	195	421	2.0e-13	43.9	COG2319	WD40 repeat	466
2918594354	366	99.69	10	365	1	325	4.4e-123	402.2	COG0523	GTPase, G3E family	323
2918594355	266	97.99	5	260	4	247	5.0e-83	272.6	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
2918594356	169	93.98	30	169	7	131	1.3e-23	77.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918594357	340	99.4	5	337	2	333	5.4e-98	322.6	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918594358	320	99.08	4	315	2	325	2.1e-94	310.2	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918594359	375	99.72	1	372	1	350	6.6e-84	276.6	COG0673	Predicted dehydrogenase	342
2918594360	270	99.63	1	270	1	269	0.0e+00	434.9	COG3718	5-deoxy-D-glucuronate isomerase	270
2918594361	302	99.28	4	293	2	277	3.6e-60	198	COG1082	Sugar phosphate isomerase/epimerase	274
2918594362	608	99.19	1	608	3	615	0.0e+00	1016	COG3962	TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism	617
2918594363	638	99.37	5	331	1	314	6.0e-86	282.1	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918594363	638	99.68	331	638	2	310	0.0e+00	489.5	COG3892	Myo-inositol catabolism protein IolC	310
2918594364	271	92.2	9	271	3	262	1.8e-73	241.4	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918594365	251	99.16	16	247	3	237	4.2e-86	282.2	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918594366	254	99.21	1	246	3	254	6.0e-87	285.4	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918594367	331	94.43	11	325	14	318	2.4e-73	241.4	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918594368	287	97.67	1	287	3	296	7.0e-76	249.9	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918594369	390	96.99	6	376	7	361	1.6e-57	189.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918594372	282	93.96	1	281	17	296	2.6e-99	326.3	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918594373	307	98.43	1	307	4	316	1.2e-109	360.9	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918594374	511	96.89	1	511	6	565	9.4e-111	365.8	COG0747	ABC-type transport system, periplasmic component	556
2918594375	606	99.46	3	565	3	551	0.0e+00	734.8	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918594377	100	78.79	17	100	15	92	5.2e-14	46.3	COG1359	Quinol monooxygenase YgiN	100
2918594378	645	92.81	11	281	1	258	1.8e-55	181.3	COG1082	Sugar phosphate isomerase/epimerase	274
2918594378	645	98.9	277	645	3	361	9.4e-128	420.5	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
2918594379	231	86.6	10	220	4	184	2.1e-22	75	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918594380	147	96.58	2	147	3	143	5.7e-65	211.7	COG0757	3-dehydroquinate dehydratase	146
2918594381	289	97.89	1	284	2	279	3.1e-82	270	COG0169	Shikimate 5-dehydrogenase	283
2918594382	252	99.17	9	249	2	241	2.2e-114	374.9	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918594383	279	94.7	6	270	7	274	3.0e-50	165.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918594384	278	94.7	5	268	5	272	2.8e-47	155.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918594385	216	91.23	2	215	19	226	8.2e-72	235.7	COG0765	ABC-type amino acid transport system, permease component	222
2918594386	222	90.79	2	219	16	222	1.8e-64	211.7	COG0765	ABC-type amino acid transport system, permease component	222
2918594387	353	76.77	6	351	5	341	1.3e-100	331.5	COG0015	Adenylosuccinate lyase	438
2918594388	206	92.11	1	206	19	228	7.3e-73	239.1	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2918594389	246	98.68	6	242	4	228	1.0e-85	281	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2918594390	139	97.58	12	132	2	122	6.3e-32	104.7	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918594391	265	96.27	1	261	5	288	3.8e-46	152.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918594392	313	98.67	6	307	2	298	5.8e-58	191.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918594393	390	99.49	1	387	2	392	1.1e-84	279.4	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918594394	307	44.19	10	103	51	107	1.9e-05	18.1	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2918594394	307	73.48	162	299	30	126	8.0e-23	74.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918594395	253	98.78	10	253	2	244	9.0e-66	215.6	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918594396	235	99.09	1	222	1	218	3.5e-92	301.9	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
2918594397	231	97.78	7	231	4	223	1.3e-89	293.7	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
2918594398	401	100	1	401	1	394	0.0e+00	449.8	COG0183	Acetyl-CoA acetyltransferase	392
2918594399	342	95.72	7	342	2	314	3.9e-48	158.3	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918594400	313	94.5	1	313	15	323	3.1e-82	270.3	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918594401	309	94.5	1	309	14	322	3.6e-80	263.6	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918594402	299	99.28	1	292	1	276	2.6e-69	228	COG1082	Sugar phosphate isomerase/epimerase	274
2918594403	336	97.44	1	328	2	343	3.4e-63	208.4	COG0673	Predicted dehydrogenase	342
2918594404	261	98.16	1	261	5	271	1.3e-129	425.7	COG4130	Predicted sugar epimerase, xylose isomerase-like family	272
2918594405	348	99.7	7	347	1	333	1.5e-81	268.6	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918594406	349	98.23	9	349	6	283	2.2e-96	316.8	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918594407	331	96.98	28	331	6	294	5.3e-85	279.6	COG1175	ABC-type sugar transport system, permease component	295
2918594408	367	99.71	1	353	1	349	0.0e+00	464.9	COG3839	ABC-type sugar transport system, ATPase component	338
2918594409	450	83.45	1	448	91	554	7.6e-115	379.4	COG5434	Polygalacturonase	542
2918594410	364	98.32	1	364	6	356	0.0e+00	450.3	COG4225	Rhamnogalacturonyl hydrolase YesR	357
2918594412	426	95.71	1	421	9	432	8.6e-47	154.8	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918594413	660	89.66	145	384	8	215	1.6e-21	70.6	COG0671	Membrane-associated phospholipid phosphatase	232
2918594414	407	28.35	79	206	274	385	2.6e-12	14	COG2814	Predicted arabinose efflux permease, MFS family	394
2918594414	407	50.38	190	407	192	390	2.6e-12	31.1	COG2814	Predicted arabinose efflux permease, MFS family	394
2918594415	809	96.86	108	809	26	795	1.6e-94	312.7	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918594416	322	96.28	8	322	12	322	2.9e-93	306.5	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918594417	168	81.72	3	166	25	176	7.6e-28	91.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918594418	381	97.1	81	378	2	302	2.4e-40	132.4	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918594419	299	50.55	6	287	6	142	1.3e-37	122.7	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2918594420	249	90.67	1	246	5	247	2.7e-51	169	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918594421	309	74.24	175	306	24	121	2.3e-24	79.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918594422	186	85.95	21	183	9	167	2.5e-33	109.4	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918594423	111	89.04	1	64	5	69	1.0e-16	55	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2918594424	199	96.59	1	199	2	199	1.5e-69	228.4	COG0605	Superoxide dismutase	204
2918594426	119	57.48	10	118	54	126	5.6e-11	37	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2918594427	355	99.15	8	348	2	351	1.1e-129	427	COG3049	Penicillin V acylase or related amidase, Ntn superfamily	353
2918594429	626	94.64	52	616	11	540	7.6e-125	411.9	COG2831	Hemolysin activation/secretion protein	554
2918594433	405	92.88	3	405	21	385	4.2e-67	216.8	COG5659	SRSO17 transposase	385
2918594434	92	48.8	2	74	57	117	3.2e-09	31.4	COG3293	Transposase	124
2918594435	98	17.99	9	93	225	294	1.5e-04	15.1	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
2918594437	1238	97.96	11	769	2	723	7.7e-125	411.8	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
2918594438	345	60.61	213	319	20	99	1.3e-04	15.6	COG2250	HEPN domain	132
2918594438	345	99.22	60	183	2	128	1.3e-17	58.1	COG1708	Predicted nucleotidyltransferase	128
2918594440	554	93.36	1	554	4	565	0.0e+00	485.7	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
2918594441	316	96.91	1	315	2	315	2.8e-111	366	COG0385	Predicted Na+-dependent transporter	319
2918594442	347	98.44	1	326	1	315	3.7e-110	362	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918594443	301	96.35	9	301	6	295	4.2e-70	231.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918594444	261	93.56	1	260	15	261	6.8e-57	186.8	COG3971	2-keto-4-pentenoate hydratase	264
2918594445	397	92.29	24	395	9	367	6.1e-48	157.7	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918594446	587	99.16	11	584	4	590	0.0e+00	550.4	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918594447	423	77.51	11	423	88	404	2.9e-26	87.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918594448	486	98.52	1	485	6	470	0.0e+00	567.5	COG2870	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase	467
2918594449	328	99.38	1	326	2	320	2.1e-52	172.9	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918594450	559	83.06	391	557	3	154	4.4e-41	132.2	COG0241	Histidinol phosphatase or a related phosphatase	181
2918594450	559	97.94	6	392	5	384	5.6e-94	309	COG2942	Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family	388
2918594451	693	98.53	345	693	3	337	2.0e-51	169.4	COG0859	ADP-heptose:LPS heptosyltransferase	334
2918594454	248	45.95	1	138	8	92	9.3e-14	45.7	COG4627	Predicted SAM-depedendent methyltransferase	185
2918594455	688	98.81	7	663	2	664	0.0e+00	541.9	COG0210	Superfamily I DNA or RNA helicase	655
2918594456	265	54.59	22	256	189	414	9.9e-59	193.5	COG4099	Predicted peptidase	387
2918594457	356	99.1	7	340	2	332	7.1e-61	200.5	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918594459	423	98.65	5	423	6	442	3.9e-54	178.9	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918594460	310	96.31	19	307	6	292	5.1e-89	292.6	COG1175	ABC-type sugar transport system, permease component	295
2918594461	280	96.47	1	279	11	283	1.5e-88	291.2	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918594462	350	99.71	1	344	1	349	0.0e+00	473.9	COG3839	ABC-type sugar transport system, ATPase component	338
2918594463	245	96.08	1	244	3	247	7.6e-92	301.4	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
2918594464	281	85.23	9	280	1	277	3.5e-93	306.3	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918594465	299	91.61	6	299	24	296	3.7e-101	332.2	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918594466	342	98.11	5	341	5	316	1.4e-106	350.6	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918594467	191	79.25	1	191	46	236	4.5e-48	158	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918594468	326	37.29	1	144	1	135	1.5e-91	90.5	COG1312	D-mannonate dehydratase	362
2918594468	326	50	143	326	179	359	1.5e-91	209.3	COG1312	D-mannonate dehydratase	362
2918594469	528	97.58	1	528	8	571	2.0e-86	285.4	COG0747	ABC-type transport system, periplasmic component	556
2918594471	779	65.01	289	777	215	645	1.8e-124	410.1	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918594471	779	98.73	4	236	3	235	1.1e-62	205.9	COG3300	MHYT domain, NO-binding membrane sensor	236
2918594472	297	99.25	48	296	2	267	8.0e-62	203.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918594474	275	98.21	1	275	4	277	1.7e-100	330	COG1273	Non-homologous end joining protein Ku, dsDNA break repair	278
2918594475	830	96.69	538	830	3	294	1.2e-113	372.7	COG3285	Eukaryotic-type DNA primase	299
2918594475	830	98.37	69	547	1	484	1.1e-124	410.9	COG1793	ATP-dependent DNA ligase	444
2918594476	263	92.47	1	263	5	262	2.7e-86	283.4	COG1273	Non-homologous end joining protein Ku, dsDNA break repair	278
2918594477	333	98.31	6	333	4	351	3.6e-102	336	COG0306	Phosphate/sulfate permease	326
2918594478	214	100	1	213	1	217	1.5e-64	211.7	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
2918594479	180	77.33	27	172	17	149	1.4e-13	45.3	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918594481	1050	99.7	2	1020	2	1012	0.0e+00	1059.1	COG0841	Multidrug efflux pump subunit AcrB	1009
2918594482	386	90.77	2	386	34	387	3.0e-42	139.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918594483	224	99.57	1	224	1	231	3.2e-62	204.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918594484	444	81.98	74	444	63	385	1.1e-51	170.9	COG0642	Signal transduction histidine kinase	336
2918594486	297	96.68	1	293	4	294	1.1e-68	226.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918594487	723	98.64	1	723	10	737	0.0e+00	1213.2	COG0376	Catalase (peroxidase I)	730
2918594489	291	65.15	120	290	40	125	4.4e-28	91.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918594490	706	96.35	10	706	30	795	1.0e-95	316.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918594491	336	91.05	5	331	27	321	4.1e-46	152	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2918594492	347	98.21	15	346	5	333	3.0e-94	310	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918594493	346	93.35	4	343	22	344	2.6e-77	254.3	COG4779	ABC-type enterobactin transport system, permease component	346
2918594494	267	98.45	4	261	2	255	4.3e-105	344.8	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
2918594495	298	97.67	6	298	1	294	3.9e-53	175.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918594496	317	98.36	1	304	5	304	2.8e-98	323	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
2918594497	504	98.57	1	457	4	484	1.2e-102	339	COG3119	Arylsulfatase A or related enzyme	475
2918594498	297	94.62	8	296	2	300	4.5e-54	177.8	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918594499	346	99.71	1	338	1	349	0.0e+00	453.4	COG3839	ABC-type sugar transport system, ATPase component	338
2918594500	504	97.82	3	474	9	457	0.0e+00	455.3	COG0165	Argininosuccinate lyase	459
2918594501	280	96.82	6	279	10	283	3.4e-92	303	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918594502	313	96.31	20	313	7	293	4.9e-85	279.7	COG1175	ABC-type sugar transport system, permease component	295
2918594503	417	97.74	1	414	7	439	7.2e-70	230.8	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918594504	408	96.77	86	396	2	301	5.7e-63	206.9	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918594505	800	91.06	22	270	8	231	1.6e-24	77.9	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
2918594506	303	90.7	16	299	18	290	3.1e-39	129.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918594508	295	80.3	163	294	20	125	6.4e-29	94.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918594509	488	99.1	1	445	3	440	0.0e+00	477.4	COG1486	Alpha-galactosidase/6-phospho-beta-glucosidase, family 4 of glycosyl hydrolase	442
2918594510	695	92.21	1	665	39	571	9.6e-95	312.8	COG0747	ABC-type transport system, periplasmic component	556
2918594511	335	99.06	1	332	1	315	1.5e-94	311.2	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918594512	378	93.29	11	378	16	293	2.5e-88	290	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918594513	555	99.44	20	555	3	533	0.0e+00	849.5	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
2918594514	457	99.32	2	449	3	441	0.0e+00	554.2	COG1486	Alpha-galactosidase/6-phospho-beta-glucosidase, family 4 of glycosyl hydrolase	442
2918594515	354	78.41	1	304	13	288	2.2e-39	129.1	COG1566	Multidrug resistance efflux pump	352
2918594516	922	46.15	706	917	59	190	7.4e-04	12.7	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
2918594516	922	73.53	12	271	7	231	0.0e+00	217.9	COG1131	ABC-type multidrug transport system, ATPase component	293
2918594516	922	75.49	277	549	4	234	0.0e+00	280	COG1131	ABC-type multidrug transport system, ATPase component	293
2918594517	372	92.15	62	371	14	283	1.5e-27	90.4	COG0842	ABC-type multidrug transport system, permease component	286
2918594519	48	68.25	1	46	16	58	5.5e-18	58.8	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918594522	147	50.89	17	136	2	115	8.3e-09	29.4	COG4565	Response regulator of citrate/malate metabolism	224
2918594524	320	89.37	2	320	9	319	7.6e-128	420.8	COG0206	Cell division GTPase FtsZ	338
2918594525	232	93.53	5	229	12	228	1.2e-56	186	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918594526	321	96.99	2	307	3	292	1.0e-72	238.7	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918594527	345	97.42	2	345	3	342	2.4e-117	386	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
2918594528	268	96.11	1	263	4	275	5.1e-56	184.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918594529	221	93.86	1	221	12	225	1.7e-58	192.2	COG0765	ABC-type amino acid transport system, permease component	222
2918594530	217	92.98	1	217	15	226	1.3e-58	192.6	COG0765	ABC-type amino acid transport system, permease component	222
2918594531	240	99.17	1	240	2	241	7.7e-109	356.7	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918594532	413	96.91	1	413	4	379	4.0e-75	247.7	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918594533	569	92.42	8	145	4	125	1.2e-47	154.2	COG1786	Swiveling domain associated with predicted aconitase	131
2918594533	569	99.5	154	557	2	402	0.0e+00	532.5	COG1679	Predicted aconitase	403
2918594534	342	99.71	1	342	1	340	0.0e+00	536.7	COG3938	Proline racemase	341
2918594535	340	98.8	1	339	3	332	7.9e-96	315.5	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918594537	267	95.05	5	266	7	275	8.8e-54	176.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918594538	234	90.35	2	219	15	220	4.7e-62	203.6	COG0765	ABC-type amino acid transport system, permease component	222
2918594539	219	93.42	1	217	14	226	1.1e-73	242	COG0765	ABC-type amino acid transport system, permease component	222
2918594540	243	97.93	2	242	3	239	1.1e-106	349.6	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918594541	311	96.64	1	311	10	325	3.7e-95	312.8	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918594542	724	64.25	145	717	215	640	2.0e-112	370.6	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918594544	209	95.68	1	194	8	184	3.4e-51	167.7	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918594546	307	98.01	1	297	3	297	2.8e-57	189	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918594547	159	94.58	1	159	8	164	6.0e-53	172.9	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2918594548	518	98.35	94	516	3	419	0.0e+00	564.5	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2918594549	960	99.18	15	960	3	972	0.0e+00	1378.7	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2918594551	550	48.83	28	280	27	213	1.5e-18	39.1	COG0477	MFS family permease	338
2918594551	550	67.36	270	550	8	265	1.5e-18	26.8	COG0477	MFS family permease	338
2918594552	298	97.32	7	298	4	294	7.2e-82	268.7	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918594553	293	96.76	1	291	11	309	4.0e-78	256.9	COG3386	Sugar lactone lactonase YvrE	307
2918594554	239	95.02	6	238	5	233	3.2e-58	191.1	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918594555	649	96.89	11	639	11	570	1.0e-92	305.9	COG0747	ABC-type transport system, periplasmic component	556
2918594556	328	99.37	1	328	1	316	7.3e-94	309	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918594557	374	94.97	5	374	13	295	1.7e-88	290.6	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918594558	574	99.46	6	551	3	551	0.0e+00	675.9	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918594559	395	98.93	1	381	4	372	2.4e-101	332.9	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918594560	288	95.21	1	288	13	310	9.3e-41	134.2	COG2017	Galactose mutarotase or related enzyme	308
2918594561	253	92.53	2	231	12	234	5.2e-56	183.8	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918594562	502	93.77	2	501	23	564	2.2e-107	354.5	COG0747	ABC-type transport system, periplasmic component	556
2918594563	315	99.37	1	314	1	316	2.7e-118	389.2	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918594564	290	95.97	5	290	10	295	5.2e-104	341.6	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918594565	594	97.43	1	594	14	544	0.0e+00	580.6	COG0405	Gamma-glutamyltranspeptidase	539
2918594566	603	99.28	1	562	4	551	0.0e+00	758	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918594567	269	99.23	5	261	3	259	3.3e-63	207.7	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2918594568	278	87.82	19	278	31	268	2.2e-14	47.1	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2918594569	370	91.78	1	336	4	327	5.7e-116	381.8	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918594570	272	92.13	3	267	13	258	1.4e-45	149.7	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918594571	294	94.44	13	294	11	282	3.8e-39	128.9	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918594572	383	87.58	1	380	4	391	9.8e-21	68.5	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918594574	67	95.52	1	65	4	67	2.0e-31	102.3	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2918594576	231	96.1	29	231	5	201	1.0e-57	189.6	COG0605	Superoxide dismutase	204
2918594577	329	98.12	9	328	6	318	1.4e-113	373.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918594578	600	99.32	14	593	3	590	0.0e+00	517.6	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918594580	535	95.7	2	534	3	514	3.4e-127	419.4	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918594581	316	54.02	2	151	39	132	1.3e-64	49	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2918594581	316	97.7	147	316	5	174	1.3e-64	168.8	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2918594582	812	99.05	1	809	9	838	0.0e+00	537.6	COG3188	Outer membrane usher protein FimD/PapC	835
2918594583	239	95.82	1	236	7	235	7.2e-45	147.2	COG3121	P pilus assembly protein, chaperone PapD	235
2918594584	165	94.25	1	165	11	174	5.0e-60	196.8	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2918594585	929	99.88	3	929	1	851	0.0e+00	1161.8	COG1049	Aconitase B	852
2918594586	211	87.37	7	175	23	188	5.6e-44	144.4	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918594587	600	50	9	115	18	85	2.0e-03	11.6	COG3631	Ketosteroid isomerase-related protein	133
2918594587	600	98.43	158	592	6	444	3.4e-114	376.6	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2918594588	357	99.72	1	355	1	352	2.5e-93	306.8	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918594589	627	99.18	1	625	5	611	0.0e+00	780.1	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
2918594590	108	17.94	2	105	362	448	3.6e-12	40.1	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2918594591	359	98.5	9	344	1	329	2.6e-66	218.3	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918594592	325	95.72	1	316	12	324	9.2e-73	239.2	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918594593	496	98.6	1	496	4	497	0.0e+00	595.4	COG1129	ABC-type sugar transport system, ATPase component	500
2918594594	338	96.24	1	327	6	312	1.2e-77	255.2	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918594595	331	94.67	8	330	11	312	6.4e-77	252.7	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918594596	274	97.48	1	270	7	277	4.1e-46	151.9	COG1082	Sugar phosphate isomerase/epimerase	274
2918594597	221	71.63	2	218	71	272	1.4e-57	188.9	COG1072	Panthothenate kinase	283
2918594598	289	94.96	1	287	6	269	4.3e-47	155.2	COG1082	Sugar phosphate isomerase/epimerase	274
2918594603	613	96.54	2	596	17	602	0.0e+00	650.3	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
2918594604	270	82.38	58	267	28	228	2.8e-36	119.2	COG2114	Adenylate cyclase, class 3	227
2918594605	162	100	1	161	1	163	4.7e-72	235.2	COG4297	Uncharacterized protein YjlB	163
2918594607	297	95.35	1	297	10	296	4.7e-28	92.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918594610	113	93.22	1	101	9	118	1.7e-22	74.3	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918594611	306	94.27	17	163	9	156	8.0e-47	33.8	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2918594611	306	98.09	156	305	3	156	8.0e-47	121.2	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2918594612	443	96.15	5	434	14	388	8.8e-31	101.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918594613	539	74.26	1	532	158	685	0.0e+00	566.2	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918594615	94	22.91	14	85	68	108	4.0e-06	21.2	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
2918594616	148	92.57	1	142	11	147	3.7e-37	121.9	COG2994	ACP:hemolysin acyltransferase (hemolysin-activating protein)	148
2918594617	707	16.47	210	402	78	147	6.2e-106	23.5	COG0840	Methyl-accepting chemotaxis protein	408
2918594617	707	74.59	390	693	108	424	6.2e-106	330.4	COG0840	Methyl-accepting chemotaxis protein	408
2918594618	287	93.02	1	286	16	295	2.0e-44	146.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918594619	230	89.93	3	224	4	244	2.9e-52	172	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918594620	400	98.99	6	400	2	393	1.4e-124	410.4	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918594621	304	91.32	16	303	13	275	4.1e-76	250.1	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918594622	267	94.76	1	266	8	260	1.9e-71	234.7	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918594623	358	95.5	4	357	7	367	2.7e-31	102.9	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918594624	367	99.15	1	366	3	352	3.6e-130	428.6	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918594625	255	98.41	1	251	2	249	1.0e-96	317.4	COG1540	Lactam utilization protein B (function unknown)	252
2918594626	332	98.73	2	323	1	312	2.0e-108	356.3	COG1984	Allophanate hydrolase subunit 2	314
2918594627	232	93.39	21	232	2	213	1.9e-63	208	COG2049	Allophanate hydrolase subunit 1	223
2918594628	146	61.9	17	146	54	144	1.1e-09	32.3	COG0511	Biotin carboxyl carrier protein	140
2918594629	463	99.33	14	461	2	448	0.0e+00	635.2	COG0439	Biotin carboxylase	449
2918594630	155	99.32	6	155	1	146	8.6e-32	105.3	COG0511	Biotin carboxyl carrier protein	140
2918594631	308	92.36	3	298	22	299	1.3e-39	130.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918594632	305	96.35	1	299	8	297	3.2e-38	125.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918594633	295	99	2	292	1	298	5.5e-50	164.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918594634	317	96.24	2	317	9	315	1.7e-85	281.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918594635	222	96.23	3	216	4	207	9.5e-57	186.2	COG0684	Regulator of RNase E activity RraA	210
2918594637	503	99.21	2	503	2	501	0.0e+00	655.2	COG3333	TctA family transporter	504
2918594638	328	98.44	1	328	2	317	1.7e-42	140.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918594639	251	92.16	1	245	3	249	1.0e-54	180.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918594640	311	99.39	1	311	1	325	2.1e-89	293.9	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918594641	267	98.37	1	237	4	245	3.5e-77	253.6	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2918594642	235	93.42	3	230	13	225	5.5e-64	209.9	COG0765	ABC-type amino acid transport system, permease component	222
2918594643	253	94.3	5	230	13	227	1.5e-65	215.2	COG0765	ABC-type amino acid transport system, permease component	222
2918594644	254	98.76	11	253	2	240	1.1e-112	369.2	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918594645	278	95.05	1	261	8	276	6.0e-54	177.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918594646	224	95.28	3	216	10	211	1.4e-64	211.8	COG0684	Regulator of RNase E activity RraA	210
2918594647	343	99.72	1	343	1	352	9.0e-96	314.9	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918594648	313	58.64	140	295	60	154	3.5e-09	30.8	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918594648	313	81.95	10	143	21	129	1.5e-17	57.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918594649	114	14.91	33	113	198	258	1.1e-04	15.2	COG0672	High-affinity Fe2+/Pb2+ permease	383
2918594650	381	96.95	9	381	2	351	1.5e-126	416.2	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2918594651	553	61.58	31	201	64	180	1.2e-32	105.2	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918594652	621	96.94	2	463	14	457	0.0e+00	539.6	COG4289	Uncharacterized protein	458
2918594653	426	97.97	3	426	5	438	6.4e-57	188.1	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918594655	369	99.71	1	362	1	349	0.0e+00	471.5	COG3839	ABC-type sugar transport system, ATPase component	338
2918594657	278	96.82	2	277	10	283	7.3e-88	288.8	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918594658	316	96.98	22	316	3	291	7.7e-103	338.1	COG1175	ABC-type sugar transport system, permease component	295
2918594661	209	85.06	1	205	34	238	1.0e-50	166.6	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918594662	336	99.39	1	329	1	325	6.5e-99	325.1	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918594663	540	99.44	1	534	3	534	0.0e+00	621.6	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918594664	416	98.47	3	193	3	195	3.0e-35	116.3	COG4961	Flp pilus assembly protein TadG	185
2918594665	292	91.42	1	292	11	319	4.7e-63	208.2	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2918594666	801	97.54	21	507	12	487	0.0e+00	646.3	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
2918594666	801	98.08	520	801	1	307	9.2e-88	288.4	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2918594667	1108	93.49	1	304	11	326	7.2e-73	239.7	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2918594667	1108	99.88	286	1108	1	807	0.0e+00	1458.6	COG4196	Uncharacterized conserved protein, DUF2126 family	808
2918594668	602	95.22	1	600	15	592	0.0e+00	600.9	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
2918594670	129	79.62	1	129	7	131	4.9e-52	170	COG1607	Acyl-CoA hydrolase	157
2918594671	747	97.76	437	747	2	263	1.1e-48	159.1	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918594671	747	99.76	1	428	2	415	0.0e+00	690.1	COG3919	Predicted ATP-dependent carboligase, ATP-grasp superfamily	415
2918594672	346	31.57	1	133	4	134	6.0e-56	80.1	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
2918594672	346	53.49	130	338	193	414	6.0e-56	103.7	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
2918594673	243	96.68	11	243	3	235	1.3e-63	208.7	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918594674	372	98.94	6	372	5	379	5.2e-111	365.3	COG1454	Alcohol dehydrogenase, class IV	377
2918594675	318	98.19	1	315	4	328	7.0e-113	371.1	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
2918594676	398	99.48	1	395	1	379	0.0e+00	537.6	COG4692	Predicted neuraminidase (sialidase)	381
2918594678	502	92.91	1	500	13	549	1.1e-94	312.6	COG0747	ABC-type transport system, periplasmic component	556
2918594679	304	99.37	1	304	1	316	1.7e-100	330.8	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918594680	307	94.3	5	298	16	296	3.9e-91	299.3	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918594681	547	99.64	1	525	2	551	0.0e+00	712.2	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918594682	293	95.65	1	293	5	290	1.2e-83	274.6	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918594686	309	97.12	7	307	3	272	5.4e-52	171.2	COG1082	Sugar phosphate isomerase/epimerase	274
2918594687	313	98.92	1	313	3	277	1.9e-47	156.2	COG1082	Sugar phosphate isomerase/epimerase	274
2918594688	390	82.34	9	380	2	290	5.6e-60	197.9	COG0673	Predicted dehydrogenase	342
2918594689	300	99.28	1	292	1	276	8.8e-70	229.6	COG1082	Sugar phosphate isomerase/epimerase	274
2918594690	272	49.3	1	267	5	251	7.0e-82	269.7	COG1129	ABC-type sugar transport system, ATPase component	500
2918594691	334	95.61	5	328	8	312	7.5e-66	216.3	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918594692	321	94.8	1	318	10	319	1.9e-45	149.3	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918594693	346	95.72	7	345	2	314	3.8e-45	148.3	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918594694	502	98.8	2	496	3	494	0.0e+00	620.6	COG2986	Histidine ammonia-lyase	498
2918594695	276	68.56	1	273	3	268	0.0e+00	473.5	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
2918594696	285	94.85	1	285	9	284	3.7e-121	398.2	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
2918594697	345	99.02	4	340	3	304	4.6e-98	322.2	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
2918594699	246	97.49	10	246	5	237	1.0e-71	235.4	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918594700	204	90.91	1	204	12	201	1.3e-28	95.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918594701	358	97.18	1	357	9	387	4.1e-60	198.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918594702	351	94.62	1	348	16	384	1.4e-48	160.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918594703	1023	99.9	5	1009	1	1013	0.0e+00	930.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2918594704	238	95.02	10	235	5	233	4.4e-58	190.5	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918594705	475	98.3	1	470	3	465	0.0e+00	725.9	COG1027	Aspartate ammonia-lyase	471
2918594706	485	98.05	12	480	7	459	0.0e+00	571.8	COG1113	L-asparagine transporter and related permeases	462
2918594707	317	92.18	1	314	23	352	7.3e-84	273.1	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
2918594709	567	99.29	2	561	4	559	0.0e+00	848.8	COG2060	K+-transporting ATPase, A chain	560
2918594711	694	99.71	3	694	2	681	0.0e+00	1131.9	COG2216	High-affinity K+ transport system, ATPase chain B	681
2918594712	188	99.47	1	186	1	188	2.6e-78	256.4	COG2156	K+-transporting ATPase, c chain	190
2918594713	900	99.11	7	900	2	890	0.0e+00	1185.8	COG2205	K+-sensing histidine kinase KdpD	890
2918594714	229	98.71	6	229	2	230	7.5e-74	242.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918594715	350	98.83	1	350	2	340	9.9e-124	406.9	COG2008	Threonine aldolase	342
2918594716	1581	97.37	1252	1581	2	297	8.8e-121	396.9	COG0070	Glutamate synthase domain 3	301
2918594716	1581	99.39	749	1246	2	487	0.0e+00	714	COG0069	Glutamate synthase domain 2	485
2918594716	1581	99.73	41	430	1	371	0.0e+00	504.8	COG0067	Glutamate synthase domain 1	371
2918594718	484	99.34	22	482	2	456	0.0e+00	561.6	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2918594719	451	92.13	105	451	24	386	3.1e-57	189.1	COG0642	Signal transduction histidine kinase	336
2918594720	224	99.14	1	223	1	230	6.3e-65	212.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918594721	411	89.55	17	367	36	352	4.5e-126	414.8	COG2845	Uncharacterized protein	354
2918594722	407	95.68	1	339	14	345	9.8e-123	404	COG2951	Membrane-bound lytic murein transglycosylase B	343
2918594723	295	98.62	4	293	2	287	4.7e-123	404	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
2918594724	497	99.57	43	497	3	468	0.0e+00	607.3	COG5338	Uncharacterized protein	468
2918594726	117	44.63	1	115	129	236	2.4e-08	28.5	COG2202	PAS domain	232
2918594727	331	99.5	13	216	2	202	3.3e-76	249.2	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
2918594728	154	98.58	7	152	2	140	6.2e-50	163.5	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
2918594729	350	97.01	5	300	6	297	1.9e-88	290.8	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918594730	344	98.44	16	342	5	320	1.1e-123	406.6	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
2918594731	644	96.21	3	539	16	523	0.0e+00	439.5	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
2918594733	481	100	1	481	1	481	0.0e+00	941.4	COG5310	Homospermidine synthase	481
2918594734	302	93.44	113	299	10	180	2.0e-44	145.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918594735	211	78.25	7	211	32	254	6.2e-37	122	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2918594736	616	98.16	21	614	11	598	0.0e+00	666.5	COG1164	Oligoendopeptidase F	598
2918594737	515	98.72	1	513	3	463	0.0e+00	591	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918594738	606	99.46	2	188	2	185	8.9e-75	244.5	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
2918594739	479	99.58	1	471	2	477	0.0e+00	576.4	COG0469	Pyruvate kinase	477
2918594740	157	95.24	1	151	8	147	6.5e-76	247.4	COG5480	Uncharacterized membrane protein	147
2918594741	262	97.34	1	259	8	263	1.5e-114	376.4	COG3931	Predicted N-formylglutamate amidohydrolase	263
2918594742	101	92.31	1	101	8	103	1.9e-54	176.7	COG3492	Uncharacterized protein	104
2918594743	84	97.65	1	84	2	84	3.8e-41	133.1	COG3750	Uncharacterized conserved protein, UPF0335 family	85
2918594744	206	39.67	13	203	133	278	2.0e-08	29.1	COG0457	Tetratricopeptide (TPR) repeat	291
2918594745	41	100	1	41	1	38	3.7e-21	69.3	COG0257	Ribosomal protein L36	38
2918594746	363	92.82	11	362	3	351	0.0e+00	474.4	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
2918594747	166	95.12	2	166	4	159	1.1e-73	240.4	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
2918594748	67	100	1	67	1	67	4.6e-42	136.5	COG5481	Uncharacterized protein	67
2918594749	58	98.25	1	57	1	56	3.6e-26	85.3	COG5570	Uncharacterized protein	57
2918594750	254	97.68	2	254	4	256	2.5e-39	129.5	COG0730	Uncharacterized membrane protein YfcA	258
2918594751	217	97.16	1	212	5	209	4.2e-43	141.1	COG0352	Thiamine monophosphate synthase	211
2918594752	364	10.27	293	345	127	160	2.7e-42	16.1	COG0790	TPR repeat	292
2918594752	364	60.73	53	302	54	254	2.7e-42	126.9	COG0790	TPR repeat	292
2918594753	266	98.07	3	260	4	257	1.5e-88	290.7	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2918594755	343	95.19	91	343	12	268	3.5e-50	165.8	COG1360	Flagellar motor protein MotB	244
2918594756	548	98.73	1	548	4	548	0.0e+00	1042.4	COG3573	Predicted oxidoreductase	552
2918594757	599	99.32	15	590	4	591	0.0e+00	594.9	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918594758	73	92	1	72	1	69	1.1e-26	87.1	COG0254	Ribosomal protein L31	75
2918594759	171	97.14	1	171	4	173	1.0e-93	306	COG5317	Uncharacterized protein	175
2918594760	63	96.92	1	63	1	63	6.3e-27	88.1	COG5509	Uncharacterized small protein, DUF1192 family	65
2918594761	429	48.56	193	408	8	193	4.6e-28	57	COG0477	MFS family permease	338
2918594761	429	49.61	2	196	5	194	4.6e-28	41.7	COG0477	MFS family permease	338
2918594763	341	100	1	335	1	332	0.0e+00	521.1	COG3588	Fructose-bisphosphate aldolase class 1	332
2918594764	400	97.99	1	400	6	395	0.0e+00	500.3	COG0126	3-phosphoglycerate kinase	395
2918594765	621	98.78	1	599	3	569	0.0e+00	806.5	COG3263	NhaP-type Na+/H+ and K+/H+ antiporter with C-terminal TrkAC and CorC domains	574
2918594767	336	98.81	2	336	1	331	0.0e+00	476.7	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
2918594768	660	99.25	2	660	4	661	0.0e+00	943.8	COG0021	Transketolase	663
2918594769	90	33.05	2	90	63	141	1.1e-03	12.8	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2918594770	125	100	1	115	1	105	2.5e-33	108.7	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
2918594772	425	97.72	1	425	4	431	3.8e-128	422.2	COG1253	Hemolysin or related protein, contains CBS domains	429
2918594773	205	97.91	4	192	3	189	5.9e-53	174.1	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
2918594774	274	99.62	1	270	1	265	9.8e-121	396.3	COG1692	Calcineurin-like phosphoesterase	266
2918594775	279	76.6	50	270	36	238	5.6e-23	73.1	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
2918594776	167	98.62	4	148	2	144	5.0e-49	160	COG3871	General stress protein 26 (function unknown)	145
2918594777	248	99.59	1	241	1	242	2.7e-101	332.4	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
2918594778	333	96.21	9	328	9	338	5.8e-69	226.8	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918594779	769	26.35	250	453	50	161	2.3e-102	31.5	COG0840	Methyl-accepting chemotaxis protein	408
2918594779	769	59.55	38	107	34	86	2.3e-03	11.5	COG1343	CRISPR/Cas system-associated endoribonuclease Cas2	89
2918594779	769	78.59	430	750	90	423	2.3e-102	313.1	COG0840	Methyl-accepting chemotaxis protein	408
2918594780	170	95.03	8	167	1	153	6.1e-65	212	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
2918594781	205	99.5	1	204	1	200	1.3e-63	208.3	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
2918594782	346	99.4	4	333	2	331	0.0e+00	510.2	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
2918594784	193	97.67	3	173	5	172	3.7e-48	158	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
2918594785	174	75	2	160	16	144	2.5e-18	60.8	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918594786	178	84.88	6	161	16	161	1.4e-11	38.8	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918594787	146	94.24	13	146	4	134	6.9e-44	143.4	COG0824	Acyl-CoA thioesterase FadM	137
2918594788	239	99.54	18	231	1	215	3.2e-76	250.4	COG0811	Biopolymer transport protein ExbB/TolQ	216
2918594789	153	94.24	14	152	8	138	1.1e-47	155.7	COG0848	Biopolymer transport protein ExbD	137
2918594790	389	26.92	23	325	144	346	8.2e-01	2.4	COG0643	Chemotaxis protein histidine kinase CheA	716
2918594791	435	99.07	10	434	4	428	0.0e+00	506.1	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2918594792	177	60.8	11	174	75	195	7.5e-45	147.5	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918594793	339	99.24	1	336	1	262	6.4e-101	331.6	COG1729	Periplasmic TolA-binding protein (function unknown)	262
2918594795	648	99.5	9	607	2	599	0.0e+00	904.6	COG0465	ATP-dependent Zn proteases	596
2918594796	450	97.28	1	450	11	475	0.0e+00	472.4	COG1109	Phosphomannomutase	464
2918594797	281	100	1	259	1	236	6.5e-50	164.5	COG3637	Opacity protein and related surface antigens	199
2918594799	392	99.46	8	384	3	370	1.0e-123	407	COG1932	Phosphoserine aminotransferase	365
2918594800	531	98.77	1	325	3	324	6.9e-124	407.3	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918594801	358	99.64	42	358	1	280	2.7e-111	365.9	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
2918594802	396	94.88	1	396	21	409	0.0e+00	498.6	COG4645	Uncharacterized protein	410
2918594803	398	99.44	10	379	2	356	4.7e-130	428.2	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
2918594808	169	99.39	5	169	2	164	1.3e-79	260.1	COG3760	Uncharacterized protein	164
2918594809	322	99.67	11	321	2	305	4.9e-121	398.3	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2918594810	215	98.19	1	215	4	220	3.6e-81	266.7	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
2918594811	62	90.91	8	62	1	60	2.9e-22	72.6	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
2918594812	1818	99.69	162	1816	5	1632	0.0e+00	1873.8	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
2918594813	692	98.64	5	692	10	733	0.0e+00	872.5	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
2918594816	387	98.73	1	387	4	391	0.0e+00	451.5	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2918594822	433	60.56	212	420	36	164	2.3e-19	60.9	COG2856	Zn-dependent peptidase ImmA, M78 family	213
2918594835	203	90.71	1	198	1	205	4.7e-28	92.5	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2918594838	286	37.23	25	266	12	186	3.5e-06	20	COG2865	Predicted transcriptional regulator, contains HTH domain	467
2918594841	703	45.71	383	457	51	98	4.6e-03	9.2	COG2739	Predicted DNA-binding protein YlxM, UPF0122 family	105
2918594841	703	65.04	9	234	3	149	1.8e-19	63.8	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2918594842	371	76.84	4	357	22	323	2.0e-102	337.7	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2918594843	378	99.08	6	355	1	323	4.1e-96	315.5	COG0523	GTPase, G3E family	323
2918594844	82	92.5	1	78	5	78	3.6e-23	75.9	COG0425	TusA-related sulfurtransferase	78
2918594845	432	100	1	306	1	300	5.2e-120	394.6	COG3034	Murein L,D-transpeptidase YafK	298
2918594846	317	98.74	1	317	2	314	0.0e+00	479.2	COG0825	Acetyl-CoA carboxylase alpha subunit	317
2918594847	328	98.67	6	321	5	300	1.5e-117	386.6	COG4974	Site-specific recombinase XerD	300
2918594849	193	97.09	21	192	3	169	2.1e-57	188.3	COG0703	Shikimate kinase	172
2918594850	377	98.61	10	376	3	357	0.0e+00	442.3	COG0337	3-dehydroquinate synthetase	360
2918594851	177	54.05	9	158	2	101	9.5e-10	33.5	COG0563	Adenylate kinase or related kinase	178
2918594852	93	95.56	1	92	1	86	3.1e-33	108.4	COG0271	Stress-induced morphogen (activity unknown)	90
2918594853	211	20.15	153	207	9	61	1.1e-20	51.4	COG2214	Curved DNA-binding protein CbpA, contains a DnaJ-like domain	237
2918594853	211	41.83	23	146	32	141	1.1e-20	16.5	COG2214	Curved DNA-binding protein CbpA, contains a DnaJ-like domain	237
2918594854	329	85.45	20	329	22	303	1.7e-62	206	COG0714	MoxR-like ATPase	329
2918594855	634	100	1	619	1	620	0.0e+00	1104.8	COG4547	Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib...	620
2918594856	325	95.29	1	325	16	339	0.0e+00	545.2	COG4246	Uncharacterized protein	340
2918594857	111	36.65	5	107	82	173	3.1e-18	60.2	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918594858	212	92.04	1	212	15	222	3.1e-63	204.8	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
2918594859	96	94.81	1	91	1	73	4.7e-34	110.9	COG0227	Ribosomal protein L28	77
2918594862	146	93.29	1	146	1	153	5.6e-61	199.8	COG3542	Predicted sugar epimerase, cupin superfamily	162
2918594863	256	90.77	2	229	24	259	2.5e-48	159.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918594864	253	40.86	12	236	118	231	9.9e-11	36.8	COG0500	SAM-dependent methyltransferase	257
2918594865	368	98.61	9	368	3	358	1.1e-109	361	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2918594866	309	99.28	4	288	2	278	8.9e-100	327.9	COG0287	Prephenate dehydrogenase	279
2918594867	333	99.11	1	333	4	338	0.0e+00	484.9	COG4093	Uncharacterized protein	338
2918594868	183	93.16	1	180	9	185	1.8e-72	237.4	COG3703	Cation transport regulator ChaC	190
2918594869	265	97.7	10	261	3	257	1.2e-50	166.6	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918594870	241	88.74	8	221	14	218	1.5e-36	120.5	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
2918594871	335	97.98	16	320	6	296	1.8e-81	267.8	COG2177	Cell division protein FtsX	297
2918594872	219	97.31	1	219	1	217	6.6e-94	308.3	COG2884	ABC-type ATPase involved in cell division	223
2918594874	180	97.21	1	180	4	177	8.2e-66	215.3	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
2918594875	119	93.98	1	119	5	129	5.3e-29	95.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918594877	422	98.23	2	394	8	395	0.0e+00	465.4	COG0019	Diaminopimelate decarboxylase	394
2918594878	67	36.21	6	67	10	30	1.8e-04	15.8	COG5567	Predicted small periplasmic lipoprotein YifL (function unknown0	58
2918594879	466	98.91	9	466	2	455	0.0e+00	682.7	COG0165	Argininosuccinate lyase	459
2918594880	222	68	60	219	15	116	2.6e-15	51.2	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2918594881	415	99.74	38	414	1	379	1.6e-95	314.6	COG3174	Uncharacterized membrane protein, DUF4010 family	371
2918594882	293	86.32	3	293	3	286	1.1e-117	387.4	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918594883	309	99.06	1	309	1	315	5.3e-106	349.3	COG2025	Electron transfer flavoprotein, alpha subunit	313
2918594884	248	99.23	1	248	1	259	6.0e-94	308.5	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2918594885	257	93.42	1	229	1	213	2.2e-58	192.1	COG0705	Membrane associated serine protease, rhomboid family	228
2918594886	192	99.46	1	192	1	184	4.8e-74	242.4	COG2096	Cob(I)alamin adenosyltransferase	184
2918594887	65	22.44	1	63	43	99	2.4e-03	11.5	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2918594888	277	78.73	1	245	4	214	6.7e-49	161.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918594889	305	90.43	1	303	17	290	3.2e-72	237.7	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2918594890	299	56.46	1	299	9	279	9.9e-91	299.7	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2918594891	218	79.58	2	218	58	287	1.3e-60	199.6	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
2918594892	472	49.28	3	66	5	38	5.5e-07	22.4	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2918594892	472	99.4	140	470	2	331	0.0e+00	479.8	COG3800	Predicted transcriptional regulator	332
2918594893	510	97.34	1	510	15	526	0.0e+00	743.6	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2918594894	298	95.81	52	271	3	208	7.1e-50	164.1	COG0625	Glutathione S-transferase	211
2918594897	667	99.85	1	667	1	645	0.0e+00	941.8	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918594898	713	96.03	562	712	3	147	4.6e-58	188.6	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
2918594898	713	99.27	8	547	3	546	0.0e+00	833	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
2918594899	138	97.95	3	132	2	144	5.6e-16	54.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918594900	514	94.6	1	514	11	518	0.0e+00	616.7	COG0578	Glycerol-3-phosphate dehydrogenase	532
2918594901	410	86.77	78	397	6	274	2.4e-32	106.6	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918594902	346	99.71	1	336	1	340	5.9e-128	421.3	COG4213	ABC-type xylose transport system, periplasmic component	341
2918594903	437	99.24	10	436	4	394	0.0e+00	532.6	COG4214	ABC-type xylose transport system, permease component	394
2918594904	260	48.5	1	254	3	245	2.9e-91	300.9	COG1129	ABC-type sugar transport system, ATPase component	500
2918594906	782	68.58	115	360	82	308	0.0e+00	31.5	COG0620	Methionine synthase II (cobalamin-independent)	330
2918594906	782	99.4	449	780	2	330	0.0e+00	441.5	COG0620	Methionine synthase II (cobalamin-independent)	330
2918594909	145	53.08	12	134	2	70	1.2e-16	56.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918594911	236	97.94	1	234	2	239	3.9e-83	272.8	COG3482	Uncharacterized protein	237
2918594912	399	96.76	1	397	10	397	5.2e-103	339	COG1944	Ribosomal protein S12 methylthiotransferase accessory factor YcaO	398
2918594914	642	32.8	437	618	51	132	2.0e-05	14.8	COG3063	Tfp pilus assembly protein PilF	250
2918594914	642	98.93	7	290	2	278	9.9e-66	216.7	COG3629	DNA-binding transcriptional activator of the SARP family	280
2918594917	379	95.48	77	378	6	301	1.8e-40	132.7	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918594918	457	97.87	1	451	5	418	1.4e-86	285.5	COG2182	Maltose-binding periplasmic protein MalE	420
2918594919	303	95.64	3	295	9	293	4.3e-58	191.3	COG1175	ABC-type sugar transport system, permease component	295
2918594920	358	95.76	22	357	13	283	9.4e-64	209.8	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918594921	370	99.43	1	344	1	348	4.2e-127	418.6	COG3839	ABC-type sugar transport system, ATPase component	338
2918594922	241	96.31	1	235	9	269	1.4e-39	130.7	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2918594923	304	93.53	7	297	13	272	6.9e-43	141.4	COG1082	Sugar phosphate isomerase/epimerase	274
2918594924	465	72.83	186	465	13	272	6.7e-82	269.4	COG2273	Beta-glucanase, GH16 family	355
2918594925	160	97.37	16	160	2	149	6.1e-33	108.4	COG0782	Transcription elongation factor, GreA/GreB family	151
2918594930	382	72.86	15	382	108	405	2.1e-47	157.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918594931	364	98.53	1	364	2	404	1.3e-37	124.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918594932	401	98.78	1	398	3	406	4.8e-35	116.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918594935	749	82.87	495	749	37	273	4.1e-50	165.1	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918594935	749	97.2	4	477	11	462	8.1e-129	424.5	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918594937	369	93.83	1	369	4	368	5.2e-53	174.8	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918594939	411	99.02	1	402	2	406	2.0e-33	111.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918594941	494	96.47	4	475	5	469	3.5e-62	204.7	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2918594942	525	93.01	93	524	24	382	2.3e-80	264.3	COG2327	Polysaccharide pyruvyl transferase family protein WcaK	385
2918594943	408	94.38	1	402	1	386	1.5e-12	41.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918594944	263	67.09	105	259	51	156	1.8e-14	48.2	COG0639	Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family	155
2918594945	201	97.91	2	201	3	189	8.7e-62	202.7	COG3672	Predicted transglutaminase-like cysteine proteinase	191
2918594947	185	100	24	167	1	155	4.4e-41	134.7	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2918594948	171	94.8	1	171	7	170	3.6e-41	135.5	COG1495	Disulfide bond formation protein DsbB	170
2918594949	470	92.54	61	388	18	327	1.3e-26	88.1	COG0582	Integrase	309
2918594951	107	83.33	1	106	18	117	9.2e-34	110.3	COG4683	Uncharacterized protein	120
2918594952	120	61.54	1	74	8	63	1.5e-04	16.1	COG5606	Predicted DNA-binding protein, XRE-type HTH domain	91
2918594955	686	6.11	1	113	1	58	9.8e-20	46	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2918594955	686	24.03	369	650	691	918	9.8e-20	9.8	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2918594955	686	28.24	155	542	379	646	9.8e-20	14.2	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2918594959	117	9.37	1	105	843	937	2.1e-19	63.4	COG0841	Multidrug efflux pump subunit AcrB	1009
2918594960	253	98.51	7	253	3	266	1.3e-53	176.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918594961	560	95.15	259	558	12	305	4.1e-97	319.1	COG3386	Sugar lactone lactonase YvrE	307
2918594961	560	99.19	10	254	2	245	1.3e-77	254.3	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918594962	327	97.82	1	322	2	315	5.5e-59	194.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918594963	360	99.71	1	355	1	349	0.0e+00	461.4	COG3839	ABC-type sugar transport system, ATPase component	338
2918594964	276	97.17	1	276	9	283	1.0e-81	269	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918594965	308	95.3	14	306	6	289	4.5e-86	283.2	COG1175	ABC-type sugar transport system, permease component	295
2918594966	423	98.87	1	423	2	439	1.7e-69	229.9	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918594967	388	91.96	19	388	24	366	2.7e-85	280.8	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918594968	302	96.32	1	299	4	291	2.4e-62	204.7	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918594969	303	97.39	1	303	4	301	6.4e-101	331.9	COG3734	2-keto-3-deoxy-galactonokinase	306
2918594970	208	75.57	35	208	48	214	1.2e-13	45.9	COG2755	Lysophospholipase L1 or related esterase	216
2918594973	143	86.18	1	131	20	150	1.6e-20	68.1	COG0782	Transcription elongation factor, GreA/GreB family	151
2918594975	336	92.31	10	331	15	302	5.1e-89	292.5	COG0630	Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase	312
2918594976	390	99.49	2	366	2	392	1.0e-114	378.4	COG2948	Type IV secretory pathway, VirB10 components	360
2918594977	248	83.15	1	246	45	271	1.7e-76	251.7	COG3504	Type IV secretory pathway, VirB9 components	265
2918594978	223	91.21	1	223	17	234	1.9e-89	293.5	COG3736	Type IV secretory pathway, component VirB8	239
2918594980	311	85.38	1	311	40	407	5.1e-76	250.7	COG3704	Type IV secretory pathway, VirB6 components	406
2918594983	793	99	1	793	6	797	0.0e+00	950.1	COG3451	Type IV secretory pathway, VirB4 component	796
2918594984	113	99.05	4	108	2	105	1.0e-45	149	COG3702	Type IV secretory pathway, VirB3 components	105
2918594985	99	93.52	1	99	2	102	9.5e-36	116.8	COG3838	Type IV secretory pathway, VirB2 components (pilins)	108
2918594989	134	97.84	1	134	4	139	7.5e-57	185.9	COG5622	Protein required for attachment to host cells	139
2918594993	141	85.83	14	132	14	116	4.0e-28	90.5	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2918594994	164	88.82	1	164	2	152	1.1e-23	78.5	COG0645	Predicted kinase	170
2918594995	193	44.44	21	169	81	164	1.9e-08	28.6	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918594996	51	13.04	1	49	244	282	3.9e-06	21	COG4973	Site-specific recombinase XerC	299
2918594997	266	68.94	120	254	31	121	2.3e-16	53.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918594998	238	48.75	4	235	45	180	4.7e-09	31.4	COG0500	SAM-dependent methyltransferase	257
2918594999	263	74.62	12	263	34	227	9.7e-33	108.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918595000	386	97.1	6	386	12	379	2.4e-126	416	COG1454	Alcohol dehydrogenase, class IV	377
2918595001	484	98.54	12	484	3	474	0.0e+00	618.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918595002	263	99.59	15	258	2	246	4.3e-71	233.2	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918595003	355	99.15	1	355	4	355	0.0e+00	547.9	COG5621	Predicted secreted hydrolase	354
2918595004	223	28.04	60	218	366	508	3.5e-21	70.4	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918595006	219	96.46	2	219	2	219	9.4e-74	241.9	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918595009	362	80.16	10	360	11	313	3.3e-40	132.6	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918595010	294	92.01	8	292	10	274	9.1e-71	232.8	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918595011	267	93.26	2	262	10	258	7.4e-61	200	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918595012	356	98.3	1	356	6	352	8.5e-125	411.1	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918595013	324	98.26	39	324	2	283	2.2e-58	192.3	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2918595014	216	89.62	14	216	16	205	6.8e-36	118.3	COG0684	Regulator of RNase E activity RraA	210
2918595015	318	96.4	1	281	3	270	1.4e-66	218.8	COG0388	Predicted amidohydrolase	274
2918595016	464	96.05	1	448	6	443	2.5e-71	235	COG2079	2-methylcitrate dehydratase PrpD	453
2918595017	365	77.58	77	353	65	320	2.1e-30	100.2	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2918595018	446	94.52	1	444	6	436	2.5e-92	304.3	COG2079	2-methylcitrate dehydratase PrpD	453
2918595020	244	98.28	3	230	3	230	5.2e-48	157.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918595021	239	80	170	237	17	80	5.8e-17	54.5	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918595022	254	95.22	2	213	4	202	4.4e-42	138.4	COG3916	N-acyl-L-homoserine lactone synthetase	209
2918595023	236	81.25	157	236	16	80	2.6e-17	56.2	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918595028	304	68.18	160	284	7	96	1.1e-05	19.3	COG2250	HEPN domain	132
2918595028	304	98.44	19	142	2	127	3.8e-16	54.2	COG1708	Predicted nucleotidyltransferase	128
2918595029	306	93.36	1	295	1	281	2.3e-65	215.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595032	440	99.5	23	437	2	398	2.6e-118	389.8	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
2918595034	1542	98.64	30	800	2	728	0.0e+00	502.9	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
2918595037	639	95.02	48	639	3	574	0.0e+00	585	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
2918595038	115	91.86	18	109	1	79	2.0e-27	90	COG3831	WGR domain, predicted DNA-binding domain in MolR	85
2918595039	92	95.74	1	92	2	91	3.9e-29	95.3	COG0776	Bacterial nucleoid DNA-binding protein	94
2918595041	103	97.2	1	103	3	106	5.4e-40	130	COG5489	Uncharacterized conserved protein, DUF736 family	107
2918595042	93	27.53	1	93	222	308	4.3e-32	106	COG4227	Antirestriction protein ArdC	316
2918595043	330	92.67	3	314	8	285	6.5e-49	161	COG4974	Site-specific recombinase XerD	300
2918595044	312	83.88	3	307	45	325	2.3e-23	77.6	COG0582	Integrase	309
2918595045	406	28.33	8	115	12	96	7.4e-40	5	COG4974	Site-specific recombinase XerD	300
2918595045	406	82.67	115	401	46	293	7.4e-40	124.6	COG4974	Site-specific recombinase XerD	300
2918595046	363	97.52	2	359	5	358	6.3e-107	352.2	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918595047	196	81.82	1	191	13	183	1.5e-25	85.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918595048	95	91.3	1	83	3	86	7.0e-08	27.3	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
2918595049	202	98.4	11	193	2	186	2.6e-77	253.1	COG2818	3-methyladenine DNA glycosylase Tag	188
2918595050	280	71.84	1	249	1	227	7.9e-115	377.7	COG4227	Antirestriction protein ArdC	316
2918595053	1087	92.65	1	1047	2	1073	0.0e+00	1096.3	COG0587	DNA polymerase III, alpha subunit	1139
2918595054	503	10.16	23	70	27	64	2.2e-56	11.7	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918595054	503	99.73	68	461	1	373	2.2e-56	175.3	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918595055	245	94.64	1	245	12	258	3.7e-108	355	COG4544	Uncharacterized conserved protein	260
2918595056	350	68.29	6	350	139	474	4.2e-106	350	COG1793	ATP-dependent DNA ligase	444
2918595057	257	98.23	1	256	1	222	3.7e-66	217	COG2135	Putative SOS response-associated peptidase YedK	226
2918595058	340	84.66	9	177	26	185	4.0e-53	174	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
2918595058	340	98.81	177	339	2	167	7.9e-44	143.8	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2918595059	134	83.94	9	133	21	135	2.0e-12	41.8	COG4319	Ketosteroid isomerase homolog	137
2918595060	170	94.67	1	156	1	142	4.6e-44	144.5	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918595061	250	88.04	5	247	2	244	2.4e-29	96.9	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2918595062	145	79.39	12	143	25	128	1.4e-19	64.7	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918595063	148	66.13	5	145	62	184	2.9e-29	96.9	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918595064	307	79.1	20	272	2	213	1.3e-45	150.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595065	227	74.42	2	226	71	294	2.4e-37	123.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595066	134	94.12	2	130	8	135	8.4e-25	81.7	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918595067	215	98.56	3	213	3	207	1.6e-46	152.6	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918595068	252	91.86	8	251	23	293	1.0e-14	49.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918595069	244	96.69	8	244	6	239	2.7e-70	231.6	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2918595070	176	99.32	7	156	2	146	1.6e-11	40	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918595071	282	98.31	10	282	5	294	2.4e-35	117.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918595072	274	91.79	1	248	5	250	1.7e-55	182.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595073	287	99	1	287	2	299	4.0e-60	198.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595074	98	87.13	1	98	7	94	3.6e-20	66.7	COG1605	Chorismate mutase	101
2918595075	194	60.75	35	190	68	180	2.0e-06	21.3	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
2918595076	258	87.54	4	258	5	257	3.0e-64	211.4	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2918595077	322	13.57	52	95	24	53	1.3e-55	2.6	COG4117	Thiosulfate reductase cytochrome b subunit	221
2918595077	322	87.33	96	315	26	218	1.3e-55	179.3	COG4117	Thiosulfate reductase cytochrome b subunit	221
2918595079	196	86.12	5	194	16	195	5.6e-16	54.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918595080	275	92.91	1	255	3	251	5.8e-56	184.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595081	303	71.97	180	298	27	121	2.2e-24	79.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918595082	229	99.13	1	229	2	229	2.2e-87	287.1	COG1794	Aspartate/glutamate racemase	230
2918595084	251	98.88	7	250	3	267	2.3e-65	215.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595085	472	50.13	267	472	9	200	4.6e-36	14.4	COG0477	MFS family permease	338
2918595085	472	83.55	13	304	3	322	4.6e-36	107	COG0477	MFS family permease	338
2918595086	226	83.73	35	226	22	196	1.9e-12	42.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918595087	269	99.25	3	267	2	267	5.4e-66	217.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595088	328	76.42	19	327	70	312	2.6e-54	179.3	COG0657	Acetyl esterase/lipase	312
2918595089	215	99.06	6	215	3	213	1.8e-33	110.5	COG4944	Uncharacterized protein	213
2918595090	179	90.32	1	179	14	181	7.0e-31	101.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918595091	261	91.53	11	260	23	292	5.8e-15	48.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918595092	299	97.32	1	299	1	291	2.1e-60	199.1	COG4823	Abortive infection bacteriophage resistance protein	299
2918595093	1084	27.39	528	635	189	271	4.8e-22	46.2	COG0863	DNA modification methylase	302
2918595093	1084	39.93	265	461	14	134	4.8e-22	24.7	COG0863	DNA modification methylase	302
2918595098	1052	5.03	951	1032	1071	1128	3.3e-71	3.9	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2918595098	1052	5.3	2	73	21	81	3.3e-71	30.8	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2918595098	1052	53.04	61	803	228	838	3.3e-71	192.7	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2918595100	446	20.31	162	438	55	107	6.7e-05	14.1	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
2918595101	151	41.48	12	129	37	92	8.9e-06	20.3	COG1310	Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif	134
2918595104	129	54.36	8	117	47	127	3.6e-04	15	COG5642	Uncharacterized conserved protein, DUF2384 family	149
2918595109	382	90.15	25	382	22	323	9.7e-25	82.2	COG0582	Integrase	309
2918595110	124	95.89	1	120	3	142	3.2e-09	30.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918595115	115	42.48	1	114	134	246	2.5e-13	44.8	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
2918595117	354	99.1	11	354	1	331	1.3e-102	338	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918595118	277	95.41	10	274	5	274	2.3e-51	169.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918595119	502	94.3	3	234	12	226	1.9e-62	205	COG0765	ABC-type amino acid transport system, permease component	222
2918595119	502	98.35	265	502	4	241	2.2e-101	332.1	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918595120	335	98.58	2	335	2	347	5.3e-81	267.2	COG0673	Predicted dehydrogenase	342
2918595121	375	96.91	7	375	7	382	1.6e-48	160.3	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918595122	404	33.05	56	218	56	94	6.6e-04	13.3	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918595125	342	78.03	72	338	2	207	1.4e-41	137.5	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918595126	407	96.21	121	403	3	256	3.3e-66	218	COG1192	Cellulose biosynthesis protein BcsQ	259
2918595127	232	91.39	2	204	2	192	1.6e-58	192.2	COG3916	N-acyl-L-homoserine lactone synthetase	209
2918595128	133	28.18	1	108	65	166	2.3e-14	47.5	COG4962	Pilus assembly protein, ATPase of CpaF family	355
2918595129	135	92.97	1	123	9	127	3.0e-31	102.5	COG3755	Uncharacterized conserved protein YecT, DUF1311 family	127
2918595131	214	97.16	6	210	2	206	3.8e-60	197.5	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918595132	477	98.93	102	471	4	374	2.0e-52	172.8	COG4585	Signal transduction histidine kinase	365
2918595134	474	98.13	2	472	3	474	6.4e-119	392.5	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918595135	376	96.65	4	376	12	415	6.8e-43	141.2	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918595136	386	98.73	1	386	4	391	3.2e-126	416	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2918595137	500	97.78	4	499	2	485	0.0e+00	497.8	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
2918595138	556	98.91	9	544	3	548	0.0e+00	671.5	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918595139	295	90.6	6	291	28	297	2.2e-86	283.9	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918595140	313	99.37	1	313	1	316	4.0e-115	379.1	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918595141	498	86.85	6	497	68	569	7.0e-70	230.7	COG0747	ABC-type transport system, periplasmic component	556
2918595142	564	89.84	61	292	2	222	1.5e-83	126.7	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918595142	564	95.93	323	562	2	237	1.5e-83	147	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918595143	188	61.62	5	180	2	115	4.0e-08	28.1	COG0563	Adenylate kinase or related kinase	178
2918595144	270	58.64	9	266	21	193	6.7e-14	44.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918595146	109	83.05	1	103	19	116	2.4e-13	45.1	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918595147	118	77.52	2	115	23	122	8.7e-22	71.5	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2918595149	295	98.34	1	295	3	298	8.1e-72	237	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595150	549	73.63	43	331	4	285	7.5e-29	95.8	COG0477	MFS family permease	338
2918595151	130	92.48	3	125	6	128	2.7e-18	60.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918595152	284	92.98	5	274	9	220	6.5e-52	170.3	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918595154	214	80.38	2	196	6	173	7.3e-10	33.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918595156	131	87.59	3	131	14	133	4.5e-33	108.7	COG4319	Ketosteroid isomerase homolog	137
2918595158	274	93.31	19	273	12	276	4.6e-48	158.3	COG2801	Transposase InsO and inactivated derivatives	232
2918595159	220	41.88	1	58	9	57	5.5e-16	19.6	COG2963	Transposase and inactivated derivatives	116
2918595159	220	41.88	52	113	7	55	5.5e-16	14.6	COG2963	Transposase and inactivated derivatives	116
2918595159	220	59.83	103	216	24	93	5.5e-16	20.5	COG2963	Transposase and inactivated derivatives	116
2918595160	193	80.38	1	192	13	180	8.6e-24	79.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918595161	308	96.01	19	302	3	291	7.0e-33	108.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918595163	548	95.33	9	545	14	564	1.6e-92	305.6	COG0747	ABC-type transport system, periplasmic component	556
2918595164	317	99.37	1	317	1	316	2.8e-98	323.7	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918595165	296	92.62	8	296	19	294	2.3e-86	283.9	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918595166	353	96.88	21	331	2	311	1.0e-109	361.1	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918595167	323	95.08	8	322	2	310	2.5e-123	405.6	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918595168	225	93.48	2	221	2	216	2.0e-41	136.2	COG4126	Asp/Glu/hydantoin racemase	230
2918595169	279	98.94	3	278	3	281	5.4e-57	187.5	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918595171	158	95.89	1	138	6	145	1.2e-37	123.5	COG0071	Molecular chaperone IbpA, HSP20 family	146
2918595173	216	98.56	6	213	2	206	7.2e-58	189.6	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918595174	146	77.4	24	145	9	121	6.2e-07	24.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918595175	164	96.69	1	149	2	147	2.5e-36	119.2	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
2918595176	317	97.34	10	307	2	294	2.9e-42	139.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595178	150	47.09	4	146	80	168	4.1e-12	40.9	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918595179	140	86	6	139	4	132	6.2e-22	72.5	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918595180	327	98.98	2	323	3	294	2.0e-45	150.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918595181	383	89.36	1	383	38	440	0.0e+00	449.9	COG5368	Uncharacterized protein	451
2918595182	215	95.13	1	214	4	218	1.1e-74	244.9	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918595183	802	25.49	209	350	362	491	7.2e-34	52.9	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918595183	802	59.02	558	797	208	508	7.2e-34	66.8	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918595184	355	99.15	1	355	4	355	0.0e+00	513.2	COG5621	Predicted secreted hydrolase	354
2918595188	267	87.71	1	261	36	299	4.9e-54	178.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595189	254	98.88	2	251	2	266	1.2e-66	219.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595191	912	70.29	671	859	4	171	1.9e-09	31	COG5571	Uncharacterized protein YhjY, contains autotransporter beta-barrel domain	239
2918595192	181	24.58	1	86	1	58	1.8e-26	21.6	COG3637	Opacity protein and related surface antigens	199
2918595192	181	47.88	63	181	124	236	1.8e-26	72.2	COG3637	Opacity protein and related surface antigens	199
2918595193	347	79.55	170	334	21	125	4.8e-17	55.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918595195	477	42.56	7	145	121	223	2.7e-32	19.7	COG2202	PAS domain	232
2918595195	477	74.79	81	275	62	242	2.7e-32	93.1	COG2202	PAS domain	232
2918595195	477	96.05	260	477	4	222	2.6e-43	141.2	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918595196	57	7.53	1	54	32	84	7.5e-10	32	COG1523	Pullulanase/glycogen debranching enzyme	697
2918595199	324	91.55	2	322	9	322	3.1e-30	99.8	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918595204	169	83.71	11	169	21	169	3.0e-05	17.7	COG1633	Rubrerythrin	176
2918595206	415	99.73	1	389	1	372	5.2e-82	270	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918595207	265	92.09	1	261	12	267	7.1e-21	69.2	COG1082	Sugar phosphate isomerase/epimerase	274
2918595208	344	97.24	12	344	5	321	9.6e-78	255.7	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918595209	389	75.11	69	233	53	218	5.2e-13	43.3	COG2755	Lysophospholipase L1 or related esterase	216
2918595210	249	98.51	2	247	3	266	8.5e-61	200.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595212	522	95.94	2	506	12	436	3.0e-39	129.9	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918595213	293	96.82	5	292	10	283	3.2e-74	244.2	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918595214	309	98.71	1	309	5	309	5.1e-129	424.4	COG4209	ABC-type polysaccharide transport system, permease component	309
2918595215	371	99.71	1	358	1	349	0.0e+00	460.1	COG3839	ABC-type sugar transport system, ATPase component	338
2918595216	262	10.78	225	259	146	170	1.2e-58	5.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918595216	262	90.95	16	235	13	223	1.2e-58	187.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918595218	224	78.5	19	207	36	192	1.3e-26	87.9	COG5620	Uncharacterized protein	200
2918595219	135	95.74	1	135	2	136	4.2e-56	183	COG5478	Low affinity Fe/Cu permease	141
2918595220	205	74.65	9	199	13	171	4.7e-17	56.9	COG0655	Multimeric flavodoxin WrbA	207
2918595223	715	98.2	27	530	6	497	0.0e+00	729	COG0753	Catalase	496
2918595224	166	98.8	1	166	1	165	2.5e-69	227	COG3685	Ferritin-like metal-binding protein YciE	167
2918595226	208	93.69	7	199	8	200	1.1e-30	101.4	COG1335	Nicotinamidase-related amidase	205
2918595230	174	90.86	10	174	10	178	3.9e-41	135.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918595231	305	42.02	1	290	349	614	4.8e-42	138.5	COG0296	1,4-alpha-glucan branching enzyme	628
2918595232	261	42.02	2	245	24	289	1.4e-86	285.5	COG0296	1,4-alpha-glucan branching enzyme	628
2918595233	517	98.77	1	479	1	483	0.0e+00	565.9	COG0297	Glycogen synthase	487
2918595236	257	97.71	5	214	4	216	3.3e-23	76.6	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918595241	248	92.66	9	212	15	216	2.1e-13	44.5	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918595247	331	98.5	5	331	1	329	1.0e-73	242.9	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918595248	317	95.41	1	315	13	324	1.9e-47	156.2	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918595249	373	97.18	21	372	6	315	4.5e-84	276.3	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918595250	262	49.3	1	259	3	249	3.1e-84	277.6	COG1129	ABC-type sugar transport system, ATPase component	500
2918595251	264	98.85	8	264	2	258	4.1e-84	276.7	COG3622	Hydroxypyruvate isomerase	260
2918595252	339	97.72	4	337	2	344	3.1e-76	251.4	COG0673	Predicted dehydrogenase	342
2918595253	309	98.2	14	303	4	276	3.5e-49	162.2	COG1082	Sugar phosphate isomerase/epimerase	274
2918595254	95	26.95	12	94	3	78	4.1e-19	63.2	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918595255	285	77.23	1	268	3	253	8.6e-82	269.3	COG2826	Transposase and inactivated derivatives, IS30 family	318
2918595257	164	97.6	1	164	3	165	2.3e-64	210.9	COG3685	Ferritin-like metal-binding protein YciE	167
2918595259	159	65.28	1	144	75	215	4.3e-45	148.4	COG3316	Transposase (or an inactivated derivative)	215
2918595261	87	42.36	1	87	2	87	4.1e-33	109.1	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
2918595262	642	92.41	265	632	8	299	5.6e-65	214.9	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2918595263	874	99.5	5	862	1	801	0.0e+00	1160.5	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918595265	289	97.21	7	289	4	282	6.7e-83	272.6	COG2890	Methylase of polypeptide chain release factors	280
2918595266	359	98.62	1	358	5	362	0.0e+00	525.1	COG0216	Protein chain release factor A	363
2918595267	755	98.54	3	755	5	749	0.0e+00	1168.9	COG3605	Signal transduction protein containing GAF and PtsI domains	756
2918595268	431	99.77	7	429	1	442	0.0e+00	491.7	COG0527	Aspartokinase	447
2918595269	615	91.92	2	603	36	513	2.0e-128	423.5	COG0513	Superfamily II DNA and RNA helicase	513
2918595270	412	98.45	2	411	1	382	0.0e+00	513.8	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
2918595271	365	93.16	1	343	26	393	2.7e-90	297.2	COG0019	Diaminopimelate decarboxylase	394
2918595272	114	88.46	5	114	10	101	4.9e-11	37.5	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2918595274	327	98.78	3	327	1	325	0.0e+00	461.7	COG1087	UDP-glucose 4-epimerase	329
2918595275	190	75	72	137	4	69	1.7e-04	15.4	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2918595276	574	25	51	142	44	100	1.5e-52	11.3	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918595276	574	92.54	329	565	13	223	1.5e-52	159.2	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918595277	327	96.93	113	326	3	223	4.8e-41	134.4	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918595278	264	26.34	1	64	16	64	2.6e-17	23	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918595278	264	32.8	66	147	122	182	2.6e-17	32.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918595280	188	91.94	1	172	11	181	1.5e-50	165.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918595281	156	94.3	5	155	4	152	8.4e-43	140.5	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918595282	1224	100	41	459	1	403	0.0e+00	549.3	COG0506	Proline dehydrogenase	391
2918595282	1224	100	459	1224	1	773	0.0e+00	1169.4	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
2918595283	275	96.81	36	274	4	246	9.0e-86	281.7	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918595284	259	94.96	2	257	12	256	3.4e-86	283.2	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918595285	317	94.93	2	315	4	321	1.7e-73	242	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918595286	509	96.66	15	497	15	477	0.0e+00	474.1	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918595287	300	98.01	9	300	2	296	1.4e-70	232.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595288	169	50.31	1	166	150	311	3.3e-63	207.9	COG0435	Glutathionyl-hydroquinone reductase	324
2918595289	154	36.96	1	130	4	122	1.4e-38	127	COG0435	Glutathionyl-hydroquinone reductase	324
2918595290	295	97.67	1	283	3	296	1.0e-40	134.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918595292	438	99.76	1	419	1	417	0.0e+00	542.4	COG1004	UDP-glucose 6-dehydrogenase	414
2918595293	340	98.75	1	336	2	318	3.8e-88	290.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918595294	348	99.37	1	333	1	313	1.0e-79	262.1	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2918595295	625	99.77	188	625	1	433	0.0e+00	681.9	COG3930	Uncharacterized protein	434
2918595299	186	96.94	5	182	3	192	1.1e-48	159.9	COG0693	Putative intracellular protease/amidase	188
2918595300	146	93.66	4	146	8	140	7.6e-47	152.8	COG1661	Predicted DNA-binding protein with PD1-like DNA-binding motif	141
2918595301	286	15.67	5	61	99	132	2.0e-88	17.1	COG4711	Uncharacterized membrane protein	217
2918595301	286	100	54	286	1	217	2.0e-88	280.7	COG4711	Uncharacterized membrane protein	217
2918595303	408	95.62	34	408	4	374	1.2e-50	167.2	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918595304	151	62.83	1	151	4	145	2.0e-48	159.4	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
2918595305	166	98.8	1	166	1	165	4.4e-73	239.1	COG3685	Ferritin-like metal-binding protein YciE	167
2918595306	778	99.87	1	778	1	772	0.0e+00	1256.5	COG4993	Glucose dehydrogenase	773
2918595307	113	25.77	9	113	107	181	2.1e-03	11.8	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
2918595308	347	85.61	192	326	16	128	3.0e-24	79.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918595309	261	98.88	1	259	3	267	8.6e-74	242.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595310	651	99.46	84	633	2	550	0.0e+00	497.9	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918595311	294	99.65	2	290	2	286	1.0e-100	331	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918595312	531	97.18	1	531	7	558	0.0e+00	520.6	COG2303	Choline dehydrogenase or related flavoprotein	542
2918595313	335	97.21	18	326	7	320	3.2e-86	283.7	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918595314	295	98.01	8	295	3	297	5.2e-85	279.9	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918595315	233	99.58	2	233	2	237	1.1e-88	290.8	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918595316	261	98.82	12	258	4	254	1.2e-90	297.5	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918595317	402	97.27	9	379	9	364	1.1e-49	163.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918595318	305	98.34	5	295	2	297	1.6e-56	186.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595319	340	94.46	7	336	17	340	5.7e-57	187.4	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918595320	372	98.12	1	372	4	369	2.0e-94	310.8	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918595321	224	93.1	1	223	10	225	5.3e-50	164.3	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918595322	489	99.16	14	485	2	471	0.0e+00	505.3	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
2918595323	281	84.38	1	280	3	272	1.7e-101	334.1	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918595324	279	83.69	3	274	1	272	2.3e-112	369.4	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918595325	304	95.64	12	304	13	297	7.0e-108	354.3	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918595326	335	99.37	1	335	1	316	1.2e-121	400.4	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918595327	534	96.54	1	534	16	573	0.0e+00	454.3	COG0747	ABC-type transport system, periplasmic component	556
2918595328	395	97.18	16	388	7	385	1.4e-86	285.2	COG0006	Xaa-Pro aminopeptidase	384
2918595330	249	97.15	1	240	8	246	1.6e-95	313.8	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2918595331	204	97.67	1	179	3	170	6.8e-56	183.2	COG3613	Nucleoside 2-deoxyribosyltransferase	172
2918595332	208	56.08	7	208	3	205	1.9e-75	248.6	COG0349	Ribonuclease D	361
2918595336	566	99.45	7	560	2	548	0.0e+00	738.8	COG0539	Ribosomal protein S1	541
2918595337	233	96.43	14	227	4	219	6.6e-69	225.1	COG0283	Cytidylate kinase	222
2918595338	128	99.22	1	128	1	128	8.2e-57	185.4	COG4530	Uncharacterized protein	129
2918595340	166	34.02	2	161	49	114	1.5e-07	24.6	COG1525	Endonuclease YncB, thermonuclease family	192
2918595341	124	45.87	1	122	128	238	2.4e-10	35	COG2202	PAS domain	232
2918595342	300	94.12	1	300	20	323	0.0e+00	499.5	COG4111	Uncharacterized conserved protein	322
2918595343	323	96	4	323	12	323	4.1e-128	421.2	COG0379	Quinolinate synthase	324
2918595344	523	96.15	5	506	11	510	0.0e+00	604.9	COG0029	Aspartate oxidase	518
2918595345	285	98.93	6	284	3	279	2.2e-114	375.6	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
2918595346	83	97.56	6	83	1	80	1.1e-23	77.6	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
2918595347	138	5.63	7	126	11	59	3.1e-03	10.3	COG4982	3-oxoacyl-ACP reductase domain of yeast-type FAS1	866
2918595349	40	97.3	1	37	1	36	3.7e-21	69.4	COG4890	Predicted outer membrane lipoprotein	37
2918595350	385	99.13	6	380	2	343	3.2e-130	428.8	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
2918595351	525	97.81	2	520	2	447	0.0e+00	644.1	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
2918595352	563	97.56	5	563	3	561	0.0e+00	601.9	COG4987	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components	573
2918595353	597	94.1	55	596	3	528	0.0e+00	579.4	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
2918595354	192	98.87	2	180	2	176	1.9e-71	233.9	COG1510	DNA-binding transcriptional regulator GbsR, MarR family	177
2918595355	343	99.72	1	342	1	352	3.6e-98	322.8	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918595356	251	99.25	6	248	2	267	1.3e-71	235.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595357	297	99.3	5	289	2	285	1.3e-92	304.4	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918595358	327	95.21	1	326	14	311	2.7e-61	201.9	COG2017	Galactose mutarotase or related enzyme	308
2918595359	153	92.41	1	150	6	151	9.6e-36	117.6	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918595360	237	99.13	1	230	1	228	2.2e-92	303.3	COG1794	Aspartate/glutamate racemase	230
2918595361	256	98.83	1	254	1	253	3.3e-75	247.3	COG0121	Predicted glutamine amidotransferase	252
2918595363	820	98.94	12	820	6	749	0.0e+00	971.6	COG0058	Glucan phosphorylase	750
2918595364	735	16.27	12	112	7	109	0.0e+00	8.7	COG0296	1,4-alpha-glucan branching enzyme	628
2918595364	735	99.68	109	733	2	632	0.0e+00	869.6	COG0296	1,4-alpha-glucan branching enzyme	628
2918595365	420	98.47	8	420	3	388	0.0e+00	517.3	COG0448	ADP-glucose pyrophosphorylase	393
2918595366	480	98.77	1	480	1	483	0.0e+00	591	COG0297	Glycogen synthase	487
2918595367	542	99.24	1	528	4	523	0.0e+00	687.7	COG0033	Phosphoglucomutase	524
2918595368	650	94.6	1	647	13	678	0.0e+00	715.8	COG1523	Pullulanase/glycogen debranching enzyme	697
2918595369	162	88.05	1	153	15	154	3.8e-43	140.7	COG2030	Acyl dehydratase	159
2918595370	345	99.14	1	345	2	348	0.0e+00	537.1	COG4427	Uncharacterized protein	350
2918595373	184	97.35	1	184	5	188	4.2e-68	223.4	COG4583	Sarcosine oxidase gamma subunit	189
2918595374	986	98.96	593	986	3	383	4.5e-126	414.7	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
2918595374	986	99.3	21	478	1	427	1.2e-89	295.6	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918595375	104	94.95	1	101	1	94	1.6e-43	141.3	COG4311	Sarcosine oxidase delta subunit	97
2918595377	417	99.48	29	407	2	387	3.9e-90	297.2	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918595378	75	98.51	1	65	2	67	1.3e-26	86.9	COG0828	Ribosomal protein S21	67
2918595379	298	69.57	22	295	90	345	1.4e-29	96.9	COG0457	Tetratricopeptide (TPR) repeat	291
2918595383	329	28.97	5	289	5	108	1.1e-21	72.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918595385	321	29.53	1	318	3	108	1.7e-23	78.6	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918595386	492	98.76	4	474	5	480	1.2e-80	265.7	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2918595387	382	85.09	3	333	17	347	4.6e-09	29.2	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918595388	263	74.23	1	263	15	279	1.2e-79	262.5	COG2273	Beta-glucanase, GH16 family	355
2918595390	332	65.18	10	287	7	240	6.5e-17	56.6	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918595391	314	34.54	11	293	3	126	3.2e-12	41.7	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918595392	331	44.57	6	275	3	162	1.7e-29	98.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918595393	301	98.97	4	294	2	288	9.5e-117	383.5	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
2918595394	782	88.46	514	781	23	275	3.4e-55	180.4	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918595394	782	98.28	7	488	6	462	0.0e+00	454	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918595395	314	95.71	6	314	15	326	7.4e-84	275.6	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918595396	991	35.34	872	985	2	83	7.0e-29	46.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918595396	991	53.02	719	867	2	124	7.0e-29	47.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918595396	991	74.11	346	705	101	392	6.3e-54	178.6	COG0642	Signal transduction histidine kinase	336
2918595397	332	98.03	1	328	6	304	6.5e-100	328.4	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
2918595398	295	98.28	5	295	3	288	1.1e-118	390.2	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
2918595399	353	86.08	2	351	2	335	0.0e+00	485.5	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
2918595400	409	99.51	6	405	2	406	2.2e-127	419.5	COG2081	Predicted flavoprotein YhiN	408
2918595401	195	97.03	1	195	4	199	2.2e-58	191.3	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
2918595402	222	73.63	2	222	78	292	3.2e-71	234.4	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2918595405	409	99.76	1	409	1	412	2.3e-118	390.1	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2918595406	338	94.1	1	338	8	342	0.0e+00	458.3	COG3569	DNA topoisomerase IB	354
2918595407	240	99.53	1	222	1	210	4.3e-43	141.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918595408	411	85.6	84	402	55	375	1.0e-57	190.3	COG4585	Signal transduction histidine kinase	365
2918595409	338	96.64	1	318	11	326	1.0e-57	189.8	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918595410	487	98.6	4	483	6	499	1.0e-130	430.5	COG1129	ABC-type sugar transport system, ATPase component	500
2918595411	313	94.98	1	312	12	314	1.0e-54	179.9	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918595412	315	95.3	1	315	7	310	9.5e-67	219.6	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918595413	306	99.03	10	306	2	307	1.6e-93	307.5	COG3386	Sugar lactone lactonase YvrE	307
2918595414	196	96.51	12	191	4	169	2.9e-37	122.4	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
2918595415	129	91.91	1	129	8	132	7.4e-47	153.2	COG3474	Cytochrome c2	135
2918595417	269	98.45	14	269	2	255	4.9e-92	302.2	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
2918595418	655	96.12	2	327	9	330	0.0e+00	205.8	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918595418	655	96.42	339	655	9	331	0.0e+00	297.4	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918595419	300	77.78	28	296	53	304	3.0e-37	122.8	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2918595420	720	98.99	9	720	9	795	0.0e+00	446.3	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918595421	303	95.68	12	303	2	289	5.4e-62	204.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595423	551	98.56	9	551	3	550	0.0e+00	615	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
2918595424	217	97.84	1	217	2	228	2.8e-68	224	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918595425	445	82.49	100	445	63	387	1.0e-40	135.1	COG0642	Signal transduction histidine kinase	336
2918595426	437	46.74	237	428	11	189	1.9e-39	33	COG0477	MFS family permease	338
2918595426	437	63.45	15	279	5	247	1.9e-39	102.4	COG0477	MFS family permease	338
2918595428	76	44.62	17	76	2	59	6.9e-05	18.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918595429	414	93.44	159	412	7	234	5.0e-54	177.3	COG2114	Adenylate cyclase, class 3	227
2918595430	330	98.58	1	330	4	349	1.1e-84	279.3	COG0673	Predicted dehydrogenase	342
2918595431	293	96.68	1	290	7	297	8.7e-39	127.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918595432	351	99.09	7	330	3	329	4.2e-108	355.8	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2918595433	306	91.91	1	301	24	307	9.3e-82	268.9	COG0010	Arginase family enzyme	305
2918595434	145	93.04	1	145	6	152	1.1e-27	91.4	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918595436	328	99.08	3	328	3	325	1.4e-106	350.4	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2918595437	431	96.64	1	422	10	441	0.0e+00	475.4	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918595438	212	99.1	1	209	1	221	1.1e-60	199.4	COG0132	Dethiobiotin synthetase	223
2918595439	383	91.54	6	377	30	386	1.2e-126	416.6	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
2918595440	344	93.79	3	341	12	328	0.0e+00	450.2	COG0502	Biotin synthase or related enzyme	335
2918595441	148	50	3	131	76	156	8.9e-11	36.7	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918595442	310	65.15	114	309	40	125	1.0e-17	57.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918595446	492	98.26	19	481	2	453	7.0e-61	200.6	COG1538	Outer membrane protein TolC	457
2918595447	449	29.34	193	331	335	476	2.6e-68	103.3	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2918595447	449	36.36	4	205	1	176	2.6e-68	128	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2918595448	158	99.37	1	157	1	157	3.9e-64	210	COG4454	Uncharacterized copper-binding protein, cupredoxin-like subfamily	158
2918595449	94	88.89	1	94	12	107	3.2e-40	131.1	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
2918595450	227	82.33	17	215	22	212	1.3e-15	52.4	COG0671	Membrane-associated phospholipid phosphatase	232
2918595451	232	98.28	5	230	3	230	3.2e-67	220.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918595452	385	90.61	5	385	29	385	1.4e-48	160.8	COG0642	Signal transduction histidine kinase	336
2918595453	317	77.41	20	285	22	254	2.4e-26	86.7	COG2990	Uncharacterized protein VirK/YbjX	300
2918595454	505	71.28	262	501	6	278	8.8e-37	14.4	COG0477	MFS family permease	338
2918595454	505	76.24	11	295	4	295	8.8e-37	108	COG0477	MFS family permease	338
2918595455	284	99	4	283	2	299	1.3e-46	154	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595456	260	97.76	4	260	2	263	2.5e-53	175.6	COG0345	Pyrroline-5-carboxylate reductase	266
2918595457	532	44.81	212	405	207	383	1.5e-16	29.7	COG2814	Predicted arabinose efflux permease, MFS family	394
2918595457	532	48.35	1	207	200	390	1.5e-16	30.9	COG2814	Predicted arabinose efflux permease, MFS family	394
2918595457	532	70.71	429	513	4	73	9.8e-05	15.9	COG1359	Quinol monooxygenase YgiN	100
2918595458	146	81.94	10	144	11	128	2.3e-22	74.2	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918595459	660	99.63	34	572	2	534	0.0e+00	618.3	COG1574	Predicted amidohydrolase YtcJ	535
2918595460	96	97.85	1	93	1	91	3.5e-41	133.6	COG4317	Xanthosine utilization system component, XapX domain	93
2918595461	230	98.06	7	208	2	203	5.7e-24	79.4	COG1335	Nicotinamidase-related amidase	205
2918595462	310	82.88	149	270	26	146	1.7e-36	24.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918595462	310	85.62	6	166	1	125	1.7e-36	98.9	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918595463	299	97.67	2	296	4	297	5.3e-69	227.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595464	359	98.05	42	359	7	308	9.2e-60	196.6	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
2918595465	154	72.89	15	153	46	166	3.8e-32	105.4	COG4925	Uncharacterized protein	166
2918595466	395	97.97	7	395	6	392	1.2e-112	370.6	COG2814	Predicted arabinose efflux permease, MFS family	394
2918595467	292	96.68	1	292	4	294	3.8e-68	224.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595469	321	70.19	1	320	2	253	1.1e-29	98.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918595470	653	94.55	1	590	34	623	0.0e+00	794.2	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918595471	385	99.2	4	371	2	372	0.0e+00	532.1	COG0562	UDP-galactopyranose mutase	374
2918595472	1730	21.31	446	527	70	95	1.1e-03	2.3	COG4518	Mu-like prophage FluMu protein gp41	122
2918595472	1730	27.87	1133	1212	62	95	1.1e-03	5.8	COG4518	Mu-like prophage FluMu protein gp41	122
2918595472	1730	30.33	859	964	58	94	1.1e-03	2.3	COG4518	Mu-like prophage FluMu protein gp41	122
2918595472	1730	32.79	1380	1474	59	98	1.1e-03	6.9	COG4518	Mu-like prophage FluMu protein gp41	122
2918595472	1730	49.18	774	857	37	96	1.1e-03	5.1	COG4518	Mu-like prophage FluMu protein gp41	122
2918595472	1730	50	975	1078	36	96	1.1e-03	11.3	COG4518	Mu-like prophage FluMu protein gp41	122
2918595473	647	24.94	18	296	37	142	9.8e-105	19.4	COG0840	Methyl-accepting chemotaxis protein	408
2918595473	647	76.24	289	594	102	425	9.8e-105	331	COG0840	Methyl-accepting chemotaxis protein	408
2918595474	191	98.41	1	188	4	189	1.4e-75	247.2	COG3506	Regulation of enolase protein 1 (function unknown), concanavalin A-like superfamily	189
2918595476	258	96.51	1	253	8	256	3.5e-79	260.2	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918595477	263	97.61	7	259	3	247	2.2e-95	313.2	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918595478	333	93.13	1	332	12	323	4.0e-61	201.4	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918595479	360	99.21	2	355	2	376	0.0e+00	498.7	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
2918595480	298	96.35	6	297	5	294	3.0e-72	238.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595481	177	88.72	40	174	14	131	2.8e-20	66.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918595482	111	73.28	3	111	27	122	2.9e-16	53.9	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918595483	38	27.82	1	38	1	37	5.6e-14	46.7	COG3607	Predicted lactoylglutathione lyase	133
2918595484	95	67.67	1	94	40	129	4.7e-29	95.4	COG3607	Predicted lactoylglutathione lyase	133
2918595485	280	96.68	2	279	1	291	1.0e-42	141.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595486	133	81.16	68	131	3	58	1.8e-21	10.7	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918595486	133	97.1	1	69	1	67	1.8e-21	58.5	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918595487	257	98.88	3	256	2	266	9.2e-63	206.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595488	207	90.91	1	201	8	197	3.8e-21	71.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918595489	268	87.12	140	267	11	125	8.8e-21	68	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918595491	676	97.08	2	672	3	668	3.7e-113	373.4	COG1289	Uncharacterized membrane protein YccC	674
2918595493	292	92.61	1	292	14	339	8.0e-82	268.4	COG1566	Multidrug resistance efflux pump	352
2918595494	422	98.42	1	417	7	442	3.8e-52	172.4	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918595495	343	92.95	1	343	17	293	2.6e-97	320.1	COG1175	ABC-type sugar transport system, permease component	295
2918595496	292	98.23	1	291	6	283	1.8e-70	232	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918595497	531	95.99	1	530	9	559	0.0e+00	495.4	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2918595498	307	99.37	1	307	1	316	4.6e-103	339.3	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918595499	376	94.97	8	376	14	296	6.2e-100	328.1	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918595500	536	99.44	3	533	2	532	0.0e+00	854	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
2918595503	401	86.92	2	365	2	320	8.7e-58	190.2	COG5351	Uncharacterized protein	367
2918595506	1458	9.11	793	890	77	154	1.1e-66	7.3	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918595506	1458	10.16	489	585	12	98	1.1e-66	34.3	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918595506	1458	12.27	545	656	23	127	1.1e-66	31.7	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918595506	1458	14.25	303	487	254	375	1.1e-66	17.2	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918595506	1458	14.6	654	795	25	149	1.1e-66	54.2	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918595506	1458	23.6	1029	1376	506	707	1.1e-66	99.3	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918595509	94	30.73	9	88	73	127	5.4e-04	14.4	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
2918595510	224	99.57	1	224	1	231	8.4e-62	202.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918595511	449	84.26	73	448	56	387	1.5e-60	200	COG0642	Signal transduction histidine kinase	336
2918595512	397	96.67	1	396	8	384	1.5e-55	183.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918595513	612	84.07	1	193	34	223	9.9e-76	247.9	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918595513	612	99.61	233	612	1	508	1.6e-78	259.4	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918595514	295	86.23	7	292	3	240	4.7e-32	105.6	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2918595515	134	90.83	12	134	10	118	1.8e-33	109	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2918595517	298	98.01	2	297	3	297	2.5e-59	195.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595518	328	81.92	52	326	20	232	5.2e-35	115.4	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918595519	206	67.82	14	189	52	169	4.4e-18	60.1	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2918595520	158	98.05	2	158	3	153	1.8e-84	275.7	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
2918595522	471	93.04	9	468	13	440	1.8e-77	255	COG0534	Na+-driven multidrug efflux pump	455
2918595523	158	84.21	27	155	6	117	7.4e-16	52.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918595525	335	89.94	6	334	11	323	0.0e+00	446.4	COG0206	Cell division GTPase FtsZ	338
2918595526	381	85.99	4	371	58	413	0.0e+00	445.2	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918595527	195	87.56	1	192	11	193	1.1e-18	63.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918595528	394	96.67	22	390	9	385	1.1e-38	127.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918595529	1037	99.9	4	1012	1	1013	0.0e+00	884.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2918595530	195	90.7	18	194	14	208	4.4e-32	100.5	COG0625	Glutathione S-transferase	211
2918595531	270	89.93	1	254	4	244	5.9e-53	174.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595534	564	66.77	347	563	13	231	0.0e+00	65.1	COG2376	Dihydroxyacetone kinase	323
2918595534	564	99.7	1	330	1	327	0.0e+00	394.1	COG2376	Dihydroxyacetone kinase	323
2918595535	152	93.04	1	151	6	152	1.1e-44	146.6	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918595536	427	98.74	12	427	4	395	2.4e-130	429.1	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2918595537	226	95.2	1	225	1	218	1.7e-121	398.1	COG5482	Uncharacterized protein	229
2918595538	326	99.67	17	319	2	306	1.8e-101	334.1	COG4286	Uncharacterized protein, UPF0160 family	306
2918595539	186	94.57	5	184	3	176	3.9e-35	115.4	COG0431	NAD(P)H-dependent FMN reductase	184
2918595540	393	93.48	2	372	20	392	4.0e-44	145.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918595541	367	93.59	11	359	18	338	5.2e-66	217.3	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918595542	370	94.46	21	351	9	332	3.9e-31	102.5	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918595543	572	98.55	20	554	5	548	0.0e+00	605.3	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918595544	281	91.61	3	281	17	289	1.7e-73	241.5	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918595545	336	98.43	3	313	3	315	6.0e-76	250.1	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918595546	551	97.58	2	551	10	573	9.8e-81	266.6	COG0747	ABC-type transport system, periplasmic component	556
2918595547	801	88.02	10	749	96	808	0.0e+00	452	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918595548	458	97.44	8	458	11	467	5.8e-121	398.8	COG0277	FAD/FMN-containing dehydrogenase	459
2918595549	200	96.55	1	196	6	201	4.0e-38	125.4	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
2918595550	190	78.95	2	186	16	180	3.1e-22	74.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918595551	342	97.73	2	314	2	303	4.5e-32	103.4	COG1893	Ketopantoate reductase	307
2918595552	280	98.15	32	219	4	215	5.5e-32	105.2	COG0778	Nitroreductase	207
2918595553	535	96.02	1	533	15	569	2.4e-102	337.9	COG0747	ABC-type transport system, periplasmic component	556
2918595554	363	73.68	260	362	6	89	1.8e-31	20.5	COG0607	Rhodanese-related sulfurtransferase	110
2918595554	363	84.21	4	107	13	108	1.8e-31	15.1	COG0607	Rhodanese-related sulfurtransferase	110
2918595554	363	95.61	124	233	5	113	1.8e-31	64.1	COG0607	Rhodanese-related sulfurtransferase	110
2918595555	414	50.13	12	216	10	201	4.4e-21	50	COG0477	MFS family permease	338
2918595555	414	53	219	412	8	210	4.4e-21	26.1	COG0477	MFS family permease	338
2918595556	285	93.69	7	284	2	283	1.1e-44	147.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595558	448	98.68	14	448	4	453	2.3e-92	304.5	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918595559	134	97.95	1	128	3	145	2.6e-14	49	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918595560	209	99.52	1	209	1	207	1.2e-43	143	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918595561	281	98.97	1	280	2	290	3.7e-77	254.1	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
2918595562	198	88.95	34	191	10	162	4.8e-15	50.1	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918595563	183	93.6	15	180	4	164	1.1e-27	91.2	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
2918595564	295	97.34	2	295	3	295	7.6e-72	236.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595566	306	98.34	1	291	1	296	3.1e-72	238.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595567	219	98.06	11	206	2	203	1.1e-21	64.6	COG1335	Nicotinamidase-related amidase	205
2918595569	302	98.01	1	295	1	295	2.3e-60	199.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595570	215	73.74	1	214	61	265	7.5e-56	183.5	COG0388	Predicted amidohydrolase	274
2918595571	221	93.87	7	216	11	209	7.7e-42	137.5	COG0684	Regulator of RNase E activity RraA	210
2918595572	346	84.13	1	339	13	330	1.2e-33	111	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918595573	357	98.58	1	355	4	351	1.5e-124	410.2	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918595574	292	92.71	9	291	11	277	3.0e-76	250.7	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918595575	264	93.63	1	261	9	258	6.2e-73	239.6	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918595576	465	99.53	6	409	2	429	2.9e-75	247.8	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
2918595577	420	17.91	191	310	197	273	4.3e-22	6.8	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918595577	420	32.09	8	184	147	284	4.3e-22	67.3	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918595578	465	90.62	1	458	8	461	2.3e-120	396.5	COG0554	Glycerol kinase	499
2918595579	317	97.21	1	316	4	317	8.1e-82	269	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918595580	183	86.02	13	181	17	176	7.4e-29	95	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918595581	265	98.06	10	265	3	255	2.7e-93	306.3	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
2918595582	328	97.31	1	327	7	332	9.6e-97	318.4	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918595583	342	97.91	8	341	5	332	1.6e-93	307.7	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918595584	305	87.96	3	305	34	318	7.3e-51	167.6	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2918595585	804	93.71	21	804	51	795	1.2e-65	216.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918595586	156	86.31	2	155	12	156	3.0e-42	138.2	COG4702	Uncharacterized protein, UPF0303 family	168
2918595587	348	99.4	6	340	1	332	8.1e-101	331.9	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918595588	337	99.15	1	331	2	349	1.3e-83	275.7	COG0673	Predicted dehydrogenase	342
2918595589	537	98.86	1	530	3	524	0.0e+00	733.4	COG4670	Acyl CoA:acetate/3-ketoacid CoA transferase	527
2918595590	259	98.11	1	255	4	263	4.5e-73	240.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918595591	506	98.33	18	492	2	472	0.0e+00	571.6	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918595592	413	94.13	1	413	16	432	4.9e-56	185.4	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918595593	292	94.97	1	291	6	288	3.0e-76	250.9	COG1175	ABC-type sugar transport system, permease component	295
2918595594	294	97.17	5	293	9	283	7.8e-79	259.3	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918595595	371	99.71	1	365	1	349	0.0e+00	471.7	COG3839	ABC-type sugar transport system, ATPase component	338
2918595596	500	97.36	1	500	6	558	1.6e-85	281.7	COG2303	Choline dehydrogenase or related flavoprotein	542
2918595597	551	97.18	1	535	7	558	0.0e+00	510.4	COG2303	Choline dehydrogenase or related flavoprotein	542
2918595598	699	84.98	37	599	6	486	6.6e-55	180.4	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918595599	271	94.81	1	271	14	287	6.2e-118	387.7	COG5473	Uncharacterized membrane protein	290
2918595600	128	81.62	7	128	22	132	1.7e-46	151.9	COG3474	Cytochrome c2	135
2918595601	271	93.7	1	271	3	240	8.0e-69	225.9	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2918595602	592	92.79	23	588	6	533	0.0e+00	670.2	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2918595603	234	92.49	16	223	14	210	2.2e-43	142.2	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918595604	240	93.9	11	240	11	210	5.9e-69	225.8	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918595605	107	90.43	1	107	11	114	3.9e-51	166.3	COG5605	Cytochrome c oxidase subunit IV	115
2918595606	245	81.4	1	244	48	292	5.4e-46	151.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595608	82	29.31	1	73	157	224	1.3e-08	28.9	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918595609	652	98.23	5	229	2	223	2.0e-85	279.4	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918595609	652	99.61	272	652	1	508	1.5e-75	249.9	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918595610	407	94.1	1	401	13	379	2.8e-59	195.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918595613	243	98.28	7	236	2	229	2.2e-80	263.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918595614	431	76.14	122	421	77	376	1.5e-44	147	COG0642	Signal transduction histidine kinase	336
2918595617	892	98.55	1	892	11	891	1.1e-76	252.4	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
2918595618	362	98.88	1	362	3	355	1.1e-117	387.4	COG3535	Uncharacterized conserved protein, DUF917 family	357
2918595619	362	98.6	1	360	5	356	3.4e-125	412.2	COG3535	Uncharacterized conserved protein, DUF917 family	357
2918595620	513	23.42	359	512	516	674	3.0e-99	15.5	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2918595620	513	55.08	1	382	3	376	3.0e-99	312.1	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2918595621	352	98.02	1	352	5	350	1.2e-129	426.9	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918595622	367	79.63	9	366	25	325	4.1e-23	76	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918595623	267	94.01	1	264	10	260	3.1e-67	220.9	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918595624	310	95.14	17	310	10	283	3.1e-80	263.9	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918595625	257	83.48	6	236	32	223	1.4e-49	162.9	COG4126	Asp/Glu/hydantoin racemase	230
2918595626	337	95.37	158	331	6	211	3.5e-12	34.6	COG0778	Nitroreductase	207
2918595627	413	97.74	86	397	2	304	1.6e-62	205.5	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918595628	355	95.11	11	347	8	318	4.5e-66	217.1	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918595629	361	96.55	37	361	7	314	1.2e-90	298	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918595630	271	48.7	1	270	6	249	4.1e-85	280.5	COG1129	ABC-type sugar transport system, ATPase component	500
2918595631	534	97.25	2	521	3	532	1.1e-99	328.3	COG1069	Ribulose kinase	544
2918595632	273	98.82	10	265	1	251	3.7e-67	220.9	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2918595633	257	99.25	6	255	2	267	1.4e-71	235.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595634	422	64.81	61	407	156	457	5.9e-12	31.5	COG4809	Archaeal ADP-dependent phosphofructokinase/glucokinase	466
2918595636	428	97.29	1	427	10	440	3.4e-51	169.2	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918595637	288	93.96	1	281	13	292	9.2e-74	242.7	COG1175	ABC-type sugar transport system, permease component	295
2918595638	277	97.17	1	276	9	283	9.6e-75	246	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918595639	374	99.71	1	354	1	349	0.0e+00	449.8	COG3839	ABC-type sugar transport system, ATPase component	338
2918595640	242	99.25	2	240	2	267	8.6e-56	183.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595642	122	37.65	1	102	73	165	1.1e-24	81.6	COG3967	Short-chain dehydrogenase involved in D-alanine esterification of teichoic acids	245
2918595643	365	99.73	10	359	1	373	1.7e-120	397	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918595644	408	96.31	2	408	12	403	1.1e-84	278.9	COG1228	Imidazolonepropionase or related amidohydrolase	406
2918595646	456	50.13	259	453	3	194	1.5e-41	28.1	COG0477	MFS family permease	338
2918595646	456	84.07	16	316	5	326	1.5e-41	115.6	COG0477	MFS family permease	338
2918595647	307	94.33	15	291	15	280	6.5e-51	167.3	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918595648	526	96.88	2	523	16	543	1.2e-119	394.8	COG0405	Gamma-glutamyltranspeptidase	539
2918595649	340	95.52	1	336	7	326	1.0e-35	118	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918595650	257	94.96	1	252	10	254	2.7e-71	234.4	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918595651	279	96.41	12	274	4	245	9.9e-84	275	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918595652	234	90.52	2	224	16	225	5.7e-52	170.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918595653	132	22.79	1	124	95	125	2.6e-03	9	COG3631	Ketosteroid isomerase-related protein	133
2918595654	412	84.67	6	401	22	380	1.2e-58	192.9	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918595655	252	78.85	1	252	71	331	7.4e-67	220.4	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918595656	126	77.5	13	126	12	104	3.0e-25	82.5	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2918595657	52	14.18	3	48	2	39	6.3e-08	27	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595658	120	42.91	1	120	146	260	7.3e-24	79.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595659	102	19.38	5	76	252	313	4.9e-20	65.9	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918595660	119	30.31	4	119	35	131	5.2e-36	118.6	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918595661	292	96.68	9	292	3	293	1.9e-52	173.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595662	411	97.34	15	407	3	368	1.7e-106	350.8	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918595663	355	99.25	11	295	2	267	3.9e-82	269.8	COG1018	Ferredoxin-NADP reductase	266
2918595664	157	57.46	3	152	114	267	1.8e-44	146.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595665	263	98.51	6	263	3	266	3.8e-55	181.5	COG0345	Pyrroline-5-carboxylate reductase	266
2918595666	332	97.07	1	332	4	334	0.0e+00	478	COG3938	Proline racemase	341
2918595667	287	95.19	1	286	8	284	4.0e-105	345.5	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
2918595668	282	95.53	1	282	6	283	2.1e-102	336.8	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
2918595669	359	86.08	5	357	3	336	0.0e+00	483.4	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
2918595670	283	95.74	1	283	7	298	1.6e-75	248.3	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
2918595671	448	98.45	33	429	4	385	7.9e-56	184.3	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918595672	505	98.96	21	498	3	476	0.0e+00	573.3	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918595673	303	97.66	1	295	4	295	8.7e-91	298	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918595674	236	90.52	1	222	19	228	1.5e-54	179.3	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918595675	343	97.54	1	330	5	321	2.8e-105	346.3	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918595676	417	99.23	29	407	3	387	1.4e-94	311.8	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918595677	106	93.94	1	102	1	93	7.7e-42	135.9	COG4311	Sarcosine oxidase delta subunit	97
2918595678	996	98.96	604	996	3	383	3.6e-125	411.7	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
2918595678	996	99.3	20	480	1	427	2.8e-88	291	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918595679	184	95.24	1	181	9	188	1.2e-52	173	COG4583	Sarcosine oxidase gamma subunit	189
2918595680	422	97.59	3	421	10	414	0.0e+00	637.4	COG0112	Glycine/serine hydroxymethyltransferase	413
2918595681	294	97.56	1	282	7	286	3.3e-130	428.1	COG0788	Formyltetrahydrofolate hydrolase	287
2918595682	408	47	6	210	8	187	6.6e-17	24.1	COG0477	MFS family permease	338
2918595682	408	48.56	206	398	8	193	6.6e-17	38.2	COG0477	MFS family permease	338
2918595683	197	80.38	1	196	7	174	1.1e-22	76.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918595684	584	90.95	64	581	42	483	7.2e-99	326	COG1785	Alkaline phosphatase	482
2918595686	229	95.61	2	222	10	227	5.2e-59	193.7	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
2918595688	152	100	24	152	1	132	5.6e-51	166.1	COG5649	Uncharacterized protein	132
2918595689	350	99.72	1	348	1	352	7.3e-85	279	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918595690	295	77.27	121	290	24	125	6.8e-24	78.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918595691	301	93.27	1	301	13	317	3.7e-76	250.4	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918595692	500	98.2	1	494	8	499	0.0e+00	633.1	COG1129	ABC-type sugar transport system, ATPase component	500
2918595693	325	93.42	19	325	12	309	1.4e-107	353.5	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918595694	243	98.78	2	242	2	244	4.4e-76	250	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2918595695	536	97.8	1	536	1	533	0.0e+00	674.4	COG1069	Ribulose kinase	544
2918595696	241	99.63	1	240	1	267	4.1e-61	201.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595697	506	50.13	257	468	5	196	3.9e-40	37.2	COG0477	MFS family permease	338
2918595697	506	54.83	24	255	5	214	3.9e-40	100.8	COG0477	MFS family permease	338
2918595698	98	27.01	4	91	106	152	1.1e-04	16.2	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
2918595699	378	83.13	31	294	41	247	7.9e-42	136.9	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918595700	298	41.7	68	296	15	210	3.4e-17	56.1	COG0515	Serine/threonine protein kinase	384
2918595701	466	92.65	241	466	10	261	1.9e-31	99.5	COG0631	Serine/threonine protein phosphatase PrpC	262
2918595701	466	99.56	11	220	1	226	8.6e-79	257	COG3913	Uncharacterized protein	227
2918595702	1159	99.83	10	1159	2	1190	0.0e+00	1196.5	COG3523	Type VI protein secretion system component VasK	1188
2918595703	500	72.36	291	472	55	198	4.2e-21	69.8	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918595703	500	98.86	23	296	2	262	2.0e-86	283.9	COG3455	Type VI protein secretion system component VasF	262
2918595704	434	97.31	1	434	13	446	0.0e+00	567.5	COG3522	Predicted component of the type VI protein secretion system	446
2918595705	399	98.38	1	399	3	427	1.1e-95	315.9	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
2918595706	334	98.81	1	329	1	331	2.3e-93	307.3	COG3520	Predicted component of the type VI protein secretion system	335
2918595707	593	100	1	593	1	621	0.0e+00	675.4	COG3519	Type VI protein secretion system component VasA	621
2918595708	169	98.73	9	168	2	156	7.5e-46	149.9	COG3518	Predicted component of the type VI protein secretion system	157
2918595709	274	99.63	1	271	2	273	1.1e-110	363.9	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion	273
2918595710	464	87.88	1	452	59	493	0.0e+00	582.3	COG3517	Predicted component of the type VI protein secretion system	495
2918595711	493	99.39	1	493	2	493	0.0e+00	736.7	COG3517	Predicted component of the type VI protein secretion system	495
2918595712	169	98.22	1	169	2	167	1.1e-71	234.3	COG3516	Predicted component of the type VI protein secretion system	169
2918595713	350	99.43	5	344	3	353	8.8e-70	230.1	COG3515	Predicted component of the type VI protein secretion system	346
2918595714	884	99.25	12	855	3	801	0.0e+00	885.1	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918595715	158	97.47	1	158	3	156	8.3e-39	127.4	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2918595718	267	42.73	6	266	5	251	4.7e-70	230.9	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2918595719	91	29.53	1	91	7	94	3.3e-19	63.8	COG1175	ABC-type sugar transport system, permease component	295
2918595720	425	99.3	2	425	2	424	0.0e+00	650.4	COG4573	Tagatose-1,6-bisphosphate aldolase non-catalytic subunit AgaZ/GatZ	426
2918595721	329	98.73	14	324	3	314	1.6e-62	205.7	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918595722	437	99.1	1	434	4	442	3.7e-71	235.1	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918595723	256	99.63	1	255	1	267	1.5e-71	235.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595724	336	98.58	1	335	4	351	7.8e-75	246.1	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918595725	344	98.2	6	344	2	329	7.7e-79	259.7	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918595726	398	44.65	209	397	8	178	2.0e-21	24.8	COG0477	MFS family permease	338
2918595726	398	59.27	10	255	11	237	2.0e-21	49.8	COG0477	MFS family permease	338
2918595727	284	43.51	3	112	50	106	3.1e-05	17.7	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918595727	284	66.67	116	274	40	127	7.4e-19	61.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918595728	296	79.55	171	295	24	128	7.4e-25	80.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918595729	423	97.07	1	419	10	439	2.2e-66	219.4	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918595730	286	95.97	1	286	7	292	1.4e-86	284.9	COG1175	ABC-type sugar transport system, permease component	295
2918595731	278	99.65	1	278	2	283	1.0e-79	262.2	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918595732	361	99.71	1	356	1	349	0.0e+00	474.6	COG3839	ABC-type sugar transport system, ATPase component	338
2918595733	667	86.25	375	667	34	309	3.1e-63	207.5	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918595733	667	96.87	4	350	2	341	6.3e-70	230.3	COG0673	Predicted dehydrogenase	342
2918595734	410	96.67	1	408	13	389	1.4e-67	222.8	COG0006	Xaa-Pro aminopeptidase	384
2918595735	105	82.44	1	105	18	125	1.3e-22	74.5	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918595736	245	95.44	9	245	8	237	4.5e-65	213.6	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918595737	265	59.19	1	204	1	190	5.9e-32	104.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918595738	274	100	4	274	1	278	1.2e-130	429.4	COG3717	5-keto 4-deoxyuronate isomerase	278
2918595739	247	99.25	5	246	2	267	1.6e-67	222.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595740	303	96.32	7	303	6	293	2.5e-74	244.1	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918595741	378	98.66	1	376	1	368	4.3e-109	358.9	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918595742	292	99.29	13	287	2	279	1.2e-75	249	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2918595743	308	60.61	166	299	48	127	5.1e-17	55.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918595744	293	95.3	1	287	9	292	3.4e-89	293.4	COG1175	ABC-type sugar transport system, permease component	295
2918595745	294	98.94	10	293	4	283	3.5e-83	273.6	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918595746	366	99.71	1	359	1	349	0.0e+00	455.8	COG3839	ABC-type sugar transport system, ATPase component	338
2918595747	422	97.97	1	421	7	440	1.9e-54	180.1	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918595748	517	97.84	1	514	1	544	1.2e-130	431.4	COG5434	Polygalacturonase	542
2918595749	378	96.92	1	364	11	356	5.5e-120	394.9	COG4225	Rhamnogalacturonyl hydrolase YesR	357
2918595750	78	97.53	1	78	3	81	3.0e-28	92.2	COG0236	Acyl carrier protein	80
2918595751	365	94.86	1	365	9	377	9.4e-57	187	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918595757	78	98.51	1	65	2	67	3.2e-25	82.2	COG0828	Ribosomal protein S21	67
2918595759	69	98.51	1	69	1	66	1.1e-34	112.6	COG1278	Cold shock protein, CspA family	67
2918595761	39	7.49	1	34	111	130	2.8e-03	11.4	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918595762	411	94.59	5	396	3	334	1.1e-75	249.5	COG0673	Predicted dehydrogenase	342
2918595763	273	97.12	4	271	5	274	8.6e-39	127.9	COG1082	Sugar phosphate isomerase/epimerase	274
2918595765	380	97.72	1	378	7	349	2.5e-62	205.7	COG0673	Predicted dehydrogenase	342
2918595766	236	84.21	17	235	11	186	1.7e-27	91.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918595767	429	99.55	3	429	2	442	4.4e-59	195.4	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918595768	317	95.97	23	314	6	291	2.1e-81	267.7	COG1175	ABC-type sugar transport system, permease component	295
2918595769	291	97.53	10	290	8	283	3.3e-91	299.8	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918595770	357	99.43	2	353	2	349	0.0e+00	471.7	COG3839	ABC-type sugar transport system, ATPase component	338
2918595771	258	71.94	3	205	5	204	3.2e-18	59.3	COG1082	Sugar phosphate isomerase/epimerase	274
2918595772	338	95.4	11	337	6	316	3.9e-86	282.9	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918595773	625	99.13	1	468	5	458	0.0e+00	737.1	COG4289	Uncharacterized protein	458
2918595774	354	98.8	10	345	3	332	7.8e-78	256.3	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918595775	430	99.1	1	429	3	441	6.1e-55	181.7	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918595776	309	99.68	1	309	1	307	0.0e+00	552.3	COG4189	Predicted transcriptional regulator	308
2918595777	503	99.61	1	503	2	510	0.0e+00	704.7	COG3534	Alpha-L-arabinofuranosidase	501
2918595778	357	98.86	1	352	4	349	0.0e+00	454.6	COG3839	ABC-type sugar transport system, ATPase component	338
2918595779	424	97.07	1	424	7	436	5.3e-65	214.9	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918595780	294	96.64	3	294	5	292	1.4e-82	271.7	COG1175	ABC-type sugar transport system, permease component	295
2918595781	275	96.82	1	274	10	283	6.4e-74	243.3	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918595782	243	97.61	1	242	3	247	1.8e-83	274.1	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918595783	289	94.57	25	281	13	256	5.0e-79	259.6	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918595784	331	81.79	4	289	6	279	1.2e-51	170.2	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918595785	442	95.04	15	419	17	342	1.9e-98	324	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918595787	373	99.71	1	349	1	349	0.0e+00	467.8	COG3839	ABC-type sugar transport system, ATPase component	338
2918595788	294	95.76	1	294	10	280	7.3e-79	259.5	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918595789	296	96.64	2	295	6	293	8.2e-72	236.3	COG1175	ABC-type sugar transport system, permease component	295
2918595790	447	97.74	1	437	5	437	1.0e-56	187.5	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918595791	157	98.01	1	151	4	151	1.5e-65	214.2	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
2918595793	594	91.76	31	545	36	425	3.9e-113	373.2	COG0840	Methyl-accepting chemotaxis protein	408
2918595795	297	33.33	25	151	154	254	1.1e-22	64.3	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2918595795	297	47.85	140	297	152	296	1.1e-22	12.2	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2918595798	326	95.28	60	318	6	247	3.9e-39	129.2	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2918595799	361	98.87	2	358	3	351	4.2e-118	388.9	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918595800	429	97.62	7	429	3	371	5.9e-46	151.2	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918595801	304	92.71	19	303	11	277	1.3e-73	242	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918595802	272	97.38	1	271	2	261	3.8e-69	227.2	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918595803	251	100	1	228	1	230	8.6e-93	304.2	COG4126	Asp/Glu/hydantoin racemase	230
2918595805	55	11.81	15	55	42	71	2.0e-03	12	COG1667	Uncharacterized protein	254
2918595806	300	19.86	28	296	696	927	9.8e-06	15.9	COG1196	Chromosome segregation ATPase	1163
2918595807	622	7.11	56	249	390	472	1.2e-08	9.4	COG1196	Chromosome segregation ATPase	1163
2918595807	622	14.73	293	549	328	499	1.2e-08	23.9	COG1196	Chromosome segregation ATPase	1163
2918595810	409	85.79	231	409	8	176	6.2e-78	77.5	COG2059	Chromate transport protein ChrA	195
2918595810	409	96.95	14	214	6	196	6.2e-78	184.2	COG2059	Chromate transport protein ChrA	195
2918595811	293	97.67	6	292	2	295	1.1e-64	213.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595812	385	93.32	2	385	19	395	3.4e-61	202	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918595813	387	90.63	1	385	28	385	3.0e-06	20.1	COG2814	Predicted arabinose efflux permease, MFS family	394
2918595814	440	94.52	10	440	9	439	1.6e-118	390.3	COG2233	Xanthine/uracil permease	451
2918595815	190	95.58	6	190	5	177	6.6e-37	121.2	COG3038	Cytochrome b561	181
2918595816	512	64.75	271	508	27	274	1.2e-32	8.9	COG0477	MFS family permease	338
2918595816	512	83.03	17	307	5	322	1.2e-32	100.6	COG0477	MFS family permease	338
2918595817	354	80.71	12	353	68	385	1.7e-44	147.3	COG0642	Signal transduction histidine kinase	336
2918595818	229	98.28	3	229	3	230	8.9e-67	219.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918595819	388	94.87	4	382	18	387	1.4e-67	222.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918595820	1026	99.7	1	1023	3	1013	0.0e+00	1115.8	COG0841	Multidrug efflux pump subunit AcrB	1009
2918595821	294	93.77	1	292	2	302	3.3e-34	113.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918595822	272	71.54	9	185	14	106	7.5e-10	33.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918595823	517	95.93	9	421	3	379	3.3e-64	211.7	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918595824	233	95.13	8	233	7	221	6.6e-49	160.9	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
2918595825	173	86.39	1	163	11	156	1.1e-10	36	COG2862	Uncharacterized membrane protein YqhA	169
2918595826	380	92.56	2	370	15	375	3.1e-52	172.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918595827	1050	99.31	5	1027	6	1012	0.0e+00	1082.1	COG0841	Multidrug efflux pump subunit AcrB	1009
2918595828	476	93.29	2	474	10	468	9.4e-71	232.7	COG0531	Amino acid transporter	466
2918595829	476	93.7	1	468	10	470	1.4e-72	239.1	COG0531	Amino acid transporter	466
2918595830	414	99.26	3	412	3	406	0.0e+00	504.6	COG2235	Arginine deiminase	409
2918595831	478	96.56	56	477	10	402	5.5e-78	256.8	COG1228	Imidazolonepropionase or related amidohydrolase	406
2918595832	345	93.33	3	342	18	353	1.6e-53	176.1	COG0628	Predicted PurR-regulated permease PerM	355
2918595833	81	87.34	1	77	3	71	2.6e-23	75.7	COG2155	Uncharacterized membrane protein YuzA, DUF378 family	79
2918595834	332	77.51	1	308	32	324	4.9e-75	247.2	COG4782	Esterase/lipase superfamily enzyme	377
2918595836	172	94.94	1	159	3	152	1.1e-47	156.3	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918595838	135	80.99	6	133	6	120	4.2e-09	30.2	COG1661	Predicted DNA-binding protein with PD1-like DNA-binding motif	141
2918595839	297	28.17	104	173	82	121	1.6e-06	11.9	COG1661	Predicted DNA-binding protein with PD1-like DNA-binding motif	141
2918595839	297	85.21	176	297	4	124	1.6e-06	8.2	COG1661	Predicted DNA-binding protein with PD1-like DNA-binding motif	141
2918595840	259	97.01	7	255	8	267	3.3e-61	201.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595841	546	97.18	15	543	9	560	2.3e-122	403.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918595842	389	100	1	388	1	394	1.0e-75	249.6	COG0183	Acetyl-CoA acetyltransferase	392
2918595843	287	99.19	17	264	1	244	2.3e-59	194.6	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918595844	267	99.25	3	262	2	267	3.8e-63	207.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595845	336	98.49	5	333	3	329	1.2e-103	341.1	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918595846	625	98.94	251	625	1	375	1.0e-107	354.9	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918595848	269	97.26	43	269	4	216	2.4e-65	214.1	COG1878	Kynurenine formamidase	218
2918595849	370	89.06	2	368	3	352	8.1e-54	177.6	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918595850	415	43.06	85	210	81	170	5.0e-80	45.1	COG2140	Oxalate decarboxylase/archaeal phosphoglucose isomerase, cupin superfamily	209
2918595850	415	98.56	207	415	2	207	5.0e-80	215.6	COG2140	Oxalate decarboxylase/archaeal phosphoglucose isomerase, cupin superfamily	209
2918595852	124	57.92	2	124	5	121	9.2e-31	101.2	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918595853	218	97.52	10	211	4	200	9.2e-88	287.3	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918595854	526	43.38	67	521	340	601	1.3e-56	185.8	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2918595855	764	96.3	13	763	29	808	0.0e+00	474.1	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918595856	172	95.54	14	169	6	155	1.5e-45	149.3	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
2918595857	326	97.63	49	326	6	293	3.7e-50	165.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918595860	440	97.97	93	440	5	293	3.6e-19	63.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918595861	472	98.33	5	472	3	473	0.0e+00	476.6	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918595862	138	96.5	1	138	5	142	5.6e-45	147.4	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2918595863	438	84.01	7	438	56	386	1.2e-48	160.6	COG0642	Signal transduction histidine kinase	336
2918595864	246	98.28	5	239	2	229	1.4e-77	254.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918595865	348	96.95	54	348	6	291	4.5e-34	112.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918595866	252	91.53	8	250	23	292	1.2e-16	55.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918595867	582	53.33	224	414	24	103	8.1e-11	36.3	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2918595867	582	93.83	1	218	12	224	7.6e-30	98.3	COG0785	Cytochrome c biogenesis protein CcdA	220
2918595869	402	97.47	17	402	3	387	2.2e-108	356.7	COG2814	Predicted arabinose efflux permease, MFS family	394
2918595870	589	83.33	180	260	5	74	1.3e-17	56.6	COG2770	HAMP domain	83
2918595870	589	93.44	409	586	11	181	2.9e-50	164	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918595871	101	29.33	5	101	211	298	2.5e-41	136.1	COG1023	6-phosphogluconate dehydrogenase (decarboxylating)	300
2918595872	545	99.28	4	540	4	551	0.0e+00	683.7	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918595873	161	75.19	30	158	29	128	2.5e-16	54.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918595874	237	97.56	1	236	3	242	2.7e-41	136.1	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2918595875	443	99.23	15	437	2	386	9.0e-105	345.3	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918595876	553	96.89	8	552	14	573	4.4e-109	360.1	COG0747	ABC-type transport system, periplasmic component	556
2918595877	316	99.37	1	316	1	316	4.6e-111	365.6	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918595878	296	94.63	4	295	14	295	2.0e-99	326.5	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918595879	441	97.42	27	415	3	380	6.0e-63	207.6	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918595880	111	56.9	2	106	42	107	2.3e-08	28.3	COG3450	Predicted enzyme of the cupin superfamily	116
2918595881	354	49.1	31	343	44	180	6.6e-11	36.8	COG0500	SAM-dependent methyltransferase	257
2918595882	592	97.71	65	501	7	432	3.5e-98	322.9	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
2918595883	268	79.93	1	247	59	293	2.2e-80	264.3	COG4302	Ethanolamine ammonia-lyase, small subunit	294
2918595884	443	92.94	1	430	21	441	0.0e+00	625.5	COG4303	Ethanolamine ammonia-lyase, large subunit	453
2918595885	262	98.07	11	261	5	258	3.7e-63	207.5	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2918595886	311	84.04	23	297	19	255	3.6e-24	79.8	COG0510	Thiamine kinase and related kinases	269
2918595887	268	47.87	57	256	121	255	5.8e-10	33.4	COG0510	Thiamine kinase and related kinases	269
2918595888	429	94.02	11	416	24	416	7.4e-37	121.4	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918595889	253	98.03	2	253	3	251	7.1e-72	236.2	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2918595890	612	99.64	1	539	1	550	0.0e+00	533.7	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918595891	305	92.95	7	301	15	291	1.5e-86	284.2	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918595892	326	98.74	3	326	3	316	4.1e-87	281.1	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918595893	527	95.85	3	524	10	563	1.7e-65	216.1	COG0747	ABC-type transport system, periplasmic component	556
2918595894	384	99.47	3	384	3	379	3.5e-115	379.2	COG1454	Alcohol dehydrogenase, class IV	377
2918595895	579	82.01	293	561	3	230	3.7e-101	121.2	COG0388	Predicted amidohydrolase	274
2918595895	579	97.84	5	271	3	274	3.7e-101	209.5	COG0388	Predicted amidohydrolase	274
2918595896	231	98.31	1	231	3	235	4.0e-84	275.8	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918595897	249	95.7	1	248	10	254	8.4e-116	380.2	COG4674	ABC-type uncharacterized transport system, ATPase component	249
2918595898	379	98.14	3	358	4	320	1.1e-84	278.8	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918595899	297	98.01	1	297	5	299	7.3e-88	289.3	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918595900	416	98.91	11	385	3	364	1.7e-69	228.9	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918595901	202	99.48	1	195	1	193	6.1e-63	206.2	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
2918595902	402	96.99	9	377	10	364	1.5e-62	206	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918595904	69	98.51	1	69	1	66	1.2e-33	109.3	COG1278	Cold shock protein, CspA family	67
2918595909	110	50	1	107	108	229	1.3e-21	71.4	COG2114	Adenylate cyclase, class 3	227
2918595910	402	97.47	17	402	3	387	1.3e-108	357.4	COG2814	Predicted arabinose efflux permease, MFS family	394
2918595916	180	91.44	6	176	7	177	1.7e-14	48.4	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918595917	101	96	2	101	2	97	5.6e-31	100	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
2918595918	652	98.79	1	651	1	655	0.0e+00	1110.5	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918595919	268	93.44	8	261	8	249	1.5e-73	241.5	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2918595921	561	98.48	7	450	2	390	1.8e-48	159.9	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2918595922	328	98.5	6	328	1	329	2.1e-70	232	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918595923	519	97.49	76	518	4	430	4.1e-105	346.2	COG1253	Hemolysin or related protein, contains CBS domains	429
2918595925	211	97.38	1	188	6	191	7.3e-77	251.8	COG3672	Predicted transglutaminase-like cysteine proteinase	191
2918595926	361	99.14	2	353	3	349	0.0e+00	448	COG3839	ABC-type sugar transport system, ATPase component	338
2918595927	275	96.82	1	275	10	283	1.7e-72	238.6	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918595928	300	94.97	3	300	11	293	6.2e-81	266.3	COG1175	ABC-type sugar transport system, permease component	295
2918595929	410	97.07	1	409	8	437	3.1e-86	284.8	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918595930	300	92.45	10	291	18	274	4.1e-51	168.3	COG1082	Sugar phosphate isomerase/epimerase	274
2918595931	332	95.44	1	332	16	350	1.8e-60	199.6	COG0673	Predicted dehydrogenase	342
2918595932	344	98.8	2	343	3	332	2.4e-85	281.1	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918595934	257	99.25	4	255	2	267	6.2e-47	154.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595935	299	98.01	2	299	3	297	4.4e-74	244.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918595936	131	94.66	1	125	7	130	1.3e-35	116.5	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918595937	340	95.72	1	322	11	323	2.6e-70	231.1	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918595938	497	98.6	1	495	7	500	0.0e+00	541.2	COG1129	ABC-type sugar transport system, ATPase component	500
2918595939	314	94.04	2	314	8	307	1.5e-70	231.9	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918595940	322	94.36	9	322	15	315	2.1e-74	244.5	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918595941	340	99.1	7	336	2	332	9.2e-112	367.9	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918595942	349	99.28	7	324	3	278	3.5e-54	178.4	COG1082	Sugar phosphate isomerase/epimerase	274
2918595943	389	98.86	10	389	3	349	2.6e-73	241.8	COG0673	Predicted dehydrogenase	342
2918595944	284	94.96	33	282	13	276	9.4e-36	117.9	COG1082	Sugar phosphate isomerase/epimerase	274
2918595945	561	97.71	1	560	5	559	1.3e-92	305.7	COG2303	Choline dehydrogenase or related flavoprotein	542
2918595947	131	91.91	1	130	11	135	8.2e-49	159.5	COG3474	Cytochrome c2	135
2918595948	233	97.25	7	219	4	215	4.5e-39	128.5	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918595949	305	94.59	1	304	15	329	4.9e-54	178.2	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918595950	380	85.33	1	379	41	453	5.6e-47	155.2	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2918595951	410	98.99	16	410	2	393	0.0e+00	530.1	COG3213	Uncharacterized protein involved in response to NO	396
2918595952	177	46.94	99	165	9	54	1.3e-06	3.1	COG4309	Uncharacterized conserved protein, DUF2249 family	98
2918595952	177	85.71	1	94	4	87	1.3e-06	17.9	COG4309	Uncharacterized conserved protein, DUF2249 family	98
2918595953	101	100	1	101	1	98	2.0e-46	150.3	COG4309	Uncharacterized conserved protein, DUF2249 family	98
2918595954	632	99.84	1	632	1	636	0.0e+00	981.4	COG4548	Nitric oxide reductase activation protein	637
2918595955	270	84.55	1	269	12	290	8.8e-51	167.2	COG0714	MoxR-like ATPase	329
2918595956	448	65.27	1	439	245	712	0.0e+00	560.8	COG3256	Nitric oxide reductase large subunit	717
2918595957	150	52.44	22	149	54	139	1.0e-06	23.1	COG2010	Cytochrome c, mono- and diheme variants	150
2918595959	177	87.32	1	177	25	210	1.7e-44	146	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918595961	225	99.54	1	225	1	218	4.9e-85	278.8	COG4094	Uncharacterized membrane protein	219
2918595962	196	97.38	2	192	3	188	4.8e-79	258.7	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
2918595963	508	99.17	15	506	3	481	0.0e+00	665.6	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
2918595964	116	99.15	1	116	1	116	1.9e-50	164.6	COG3189	Uncharacterized conserved protein YeaO, DUF488 family	117
2918595965	171	96.43	1	168	5	166	3.1e-59	193.6	COG3154	Predicted lipid carrier protein YhbT, SCP2 domain	168
2918595966	325	87.43	1	325	6	311	9.7e-97	318.4	COG0826	Collagenase-like protease, PrtC family	347
2918595967	312	88	9	311	3	310	6.9e-65	213.5	COG0826	Collagenase-like protease, PrtC family	347
2918595969	328	81.79	1	317	6	279	1.8e-26	87.5	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918595970	269	94.96	8	262	12	256	7.2e-51	167.2	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918595971	250	96.91	1	250	8	258	8.4e-91	298.4	COG4525	ABC-type taurine transport system, ATPase component	259
2918595972	395	97.47	1	392	10	395	2.0e-120	397.1	COG3213	Uncharacterized protein involved in response to NO	396
2918595973	61	100	1	61	1	62	2.7e-34	110.1	COG4459	Periplasmic nitrate reductase system, NapE component	62
2918595974	166	53.23	87	162	44	109	4.5e-21	35.8	COG1145	Ferredoxin	99
2918595974	166	55.65	4	97	38	106	4.5e-21	37.3	COG1145	Ferredoxin	99
2918595975	95	97.87	1	95	3	94	6.4e-33	107	COG3062	Cytoplasmic chaperone NapD for the signal peptide of periplasmic nitrate reductase NapAB	94
2918595976	834	99.75	4	834	2	809	0.0e+00	708	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918595977	154	94.84	1	148	8	154	2.7e-64	210.2	COG3043	Nitrate reductase cytochrome c-type subunit	155
2918595978	233	98.42	10	201	3	189	3.2e-91	298.6	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
2918595979	637	99.68	16	637	2	622	0.0e+00	769.6	COG3211	Secreted phosphatase, PhoX family	616
2918595980	237	95.61	14	235	10	227	3.3e-69	227.2	COG2977	4'-phosphopantetheinyl transferase EntD (siderophore biosynthesis)	228
2918595981	251	98.88	4	248	2	266	6.9e-66	216.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918595982	289	93.24	218	289	1	69	2.6e-24	78.5	COG3433	Aryl carrier domain	74
2918595982	289	96.79	1	219	1	211	3.1e-100	328.3	COG1535	Isochorismate hydrolase	218
2918595983	541	98.34	1	538	4	536	0.0e+00	826	COG1021	Non-ribosomal peptide synthetase component E (peptide arylation enzyme)	542
2918595984	391	90.35	2	391	40	423	1.8e-124	410.5	COG1169	Isochorismate synthase EntC	423
2918595985	1485	33.64	229	469	4	221	5.0e-93	75.4	COG1020	Non-ribosomal peptide synthetase component F	642
2918595985	1485	98.46	674	1312	11	648	5.0e-93	235.4	COG1020	Non-ribosomal peptide synthetase component F	642
2918595987	942	86.42	412	488	8	77	9.1e-05	16.1	COG0236	Acyl carrier protein	80
2918595988	92	90.54	19	91	3	69	1.3e-16	54.1	COG3433	Aryl carrier domain	74
2918595989	279	96.62	10	274	7	263	1.8e-78	257.8	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
2918595990	317	95.37	1	316	9	317	2.8e-27	90.1	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2918595991	354	96.12	22	350	10	331	5.2e-64	210.6	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918595992	337	97.31	1	327	5	330	1.3e-69	229.1	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918595993	263	96.9	1	255	3	252	3.7e-82	269.7	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
2918595994	433	95.34	14	420	17	343	6.5e-77	253.2	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918595995	258	96.34	21	257	1	237	2.7e-49	161.6	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918595997	688	92.96	1	688	27	765	2.2e-70	231.1	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918595998	395	98.5	10	394	3	395	1.8e-102	337.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918595999	306	98.34	10	301	3	298	3.5e-63	208.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918596000	353	99.4	8	337	2	333	1.8e-77	255.1	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918596001	340	85.71	1	338	12	335	5.0e-48	158.3	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918596002	275	92.36	2	275	15	280	1.7e-79	261.4	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918596003	259	94.01	1	258	10	260	6.9e-71	232.9	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918596004	341	96.32	2	339	4	343	1.2e-115	380.8	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918596005	306	98.72	1	304	4	312	1.6e-79	261.7	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
2918596006	597	98.63	9	592	7	582	0.0e+00	625.5	COG1001	Adenine deaminase	584
2918596007	307	97.01	1	300	1	292	1.2e-62	206.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918596008	415	94.68	27	414	12	385	5.8e-32	104.8	COG2814	Predicted arabinose efflux permease, MFS family	394
2918596009	390	98.98	1	390	3	391	2.4e-129	426.2	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2918596010	235	93.85	27	222	9	176	9.7e-31	100.8	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
2918596011	351	99.69	2	349	2	318	6.4e-111	364.8	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
2918596012	546	98.1	2	546	7	573	1.1e-93	309.3	COG0747	ABC-type transport system, periplasmic component	556
2918596013	355	96.86	21	355	9	316	1.9e-111	366.7	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918596014	310	95.3	18	310	13	296	7.7e-107	350.9	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918596015	278	85.23	5	277	1	277	1.1e-106	350.7	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918596016	249	98.43	2	249	2	252	1.1e-94	310.9	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
2918596017	314	99	15	314	1	298	5.5e-58	191.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918596018	511	96.02	1	510	11	565	6.4e-103	339.8	COG0747	ABC-type transport system, periplasmic component	556
2918596019	316	99.37	1	315	1	316	2.6e-114	376.2	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918596020	272	90.94	1	272	25	295	5.9e-81	266	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918596021	465	99.79	1	461	1	480	2.1e-119	393.9	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918596022	188	97.45	1	188	1	191	5.4e-50	164.3	COG0693	Putative intracellular protease/amidase	188
2918596023	116	99.02	1	106	1	101	2.0e-43	140.6	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918596024	306	94.97	8	305	13	295	8.5e-88	288.2	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918596025	336	99.37	1	336	1	316	1.6e-100	330.4	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918596026	569	97.58	1	569	10	573	1.2e-87	289.5	COG0747	ABC-type transport system, periplasmic component	556
2918596027	387	98.73	1	387	4	391	0.0e+00	449.3	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2918596028	616	99.28	8	574	4	551	0.0e+00	751.1	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918596029	317	96.56	1	317	9	317	3.0e-101	332.9	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
2918596030	437	96.61	1	434	15	442	2.1e-76	252.4	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918596033	343	91.17	9	277	8	265	1.2e-45	150	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918596034	394	92.19	23	392	30	395	1.3e-105	348.3	COG4597	ABC-type amino acid transport system, permease component	397
2918596035	368	89.04	132	355	22	224	9.4e-57	186.7	COG0765	ABC-type amino acid transport system, permease component	222
2918596037	351	99.69	9	332	2	325	3.0e-101	333.3	COG3491	Isopenicillin N synthase and related dioxygenases	322
2918596038	324	84.44	14	320	38	330	1.9e-42	139.7	COG3239	Fatty acid desaturase	343
2918596040	520	94.46	5	518	11	556	4.1e-86	284.3	COG0747	ABC-type transport system, periplasmic component	556
2918596041	326	96.86	6	318	8	315	3.5e-98	323.1	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918596042	277	90.94	3	276	27	297	5.9e-88	288.9	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918596043	324	98.46	5	323	2	321	1.9e-108	356.6	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918596044	324	89.69	6	302	25	311	7.7e-90	295.6	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918596045	268	83.72	4	263	42	293	6.6e-26	85.5	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
2918596046	538	96.64	13	529	3	549	2.2e-65	209.4	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918596047	106	91.78	1	65	3	69	1.2e-13	43.5	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2918596048	348	95.41	1	331	11	322	2.1e-40	132.8	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918596049	493	95.41	1	488	7	484	0.0e+00	462.9	COG1129	ABC-type sugar transport system, ATPase component	500
2918596050	344	95.92	18	343	5	310	1.4e-79	261.6	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918596051	348	92.97	1	339	13	316	2.4e-39	129.6	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918596052	417	97.84	2	417	8	369	1.0e-123	407.4	COG5276	Uncharacterized conserved protein	370
2918596053	347	96.56	13	336	3	311	6.3e-97	318.7	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918596054	420	95.99	27	416	15	397	9.0e-66	216.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918596055	422	90.98	32	417	21	383	6.2e-55	181.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918596056	481	96.44	7	479	4	463	1.7e-130	430.2	COG4529	Uncharacterized NAD(P)/FAD-binding protein YdhS	474
2918596057	472	94.75	10	422	17	341	2.1e-82	271.4	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918596058	333	96.55	13	332	7	314	1.1e-64	212.6	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918596059	354	96.55	37	354	7	314	1.6e-56	185.7	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918596060	519	99	12	511	4	499	0.0e+00	556.1	COG1129	ABC-type sugar transport system, ATPase component	500
2918596061	335	96.33	10	333	8	322	4.9e-43	141.4	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918596062	440	95.92	11	412	12	340	4.3e-67	221	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918596063	551	98.91	1	551	3	548	0.0e+00	617.5	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918596064	290	90.6	4	290	25	294	2.9e-85	280.2	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918596065	338	97.8	26	333	6	316	1.3e-78	259	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918596066	540	95.67	1	538	12	564	1.3e-88	292.7	COG0747	ABC-type transport system, periplasmic component	556
2918596067	545	96.19	1	543	8	563	3.6e-87	288	COG0747	ABC-type transport system, periplasmic component	556
2918596068	333	94.75	6	331	16	340	3.7e-49	161.9	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918596069	234	63.58	13	147	52	154	1.2e-10	36.1	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918596070	340	13.7	249	316	295	341	2.2e-24	8.3	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918596070	340	46.06	7	211	17	174	2.2e-24	72.4	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918596071	422	94.75	17	406	18	342	1.6e-74	244.8	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918596072	318	99.34	4	314	2	301	1.8e-95	313.8	COG0031	Cysteine synthase	300
2918596074	626	97.98	63	626	11	544	0.0e+00	652.7	COG0405	Gamma-glutamyltranspeptidase	539
2918596075	417	95.64	1	417	17	411	9.4e-63	206.6	COG1373	Predicted ATPase, AAA+ superfamily	398
2918596076	78	74.74	1	78	24	94	5.9e-27	88.9	COG3514	Uncharacterized conserved protein, DUF4415 family	93
2918596077	129	96.21	1	129	4	130	9.0e-36	117.6	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
2918596079	301	95.99	8	300	6	292	2.0e-75	247.6	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918596080	401	98.48	6	400	4	393	3.4e-117	386.2	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918596081	545	95.22	5	545	4	541	6.6e-113	372.1	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
2918596082	696	99.26	6	693	2	675	0.0e+00	553.9	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2918596083	265	93.64	1	256	10	274	8.4e-44	144.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918596084	216	91.67	2	216	18	226	3.7e-71	233.7	COG0765	ABC-type amino acid transport system, permease component	222
2918596085	222	91.67	2	219	16	224	8.8e-65	212.8	COG0765	ABC-type amino acid transport system, permease component	222
2918596086	251	99.17	9	249	2	241	9.8e-116	379.4	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918596087	157	88.24	8	155	16	135	1.8e-18	61.2	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918596088	250	93.36	2	242	12	236	2.4e-54	178.6	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918596089	355	92.8	4	352	14	348	7.5e-43	141.2	COG3177	Fic family protein	348
2918596090	285	51.41	1	279	269	560	8.4e-52	165.9	COG2303	Choline dehydrogenase or related flavoprotein	542
2918596091	252	42.43	19	251	7	247	9.2e-50	164.2	COG2303	Choline dehydrogenase or related flavoprotein	542
2918596092	265	96.61	11	261	8	292	4.3e-19	63.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918596093	155	76.69	22	146	6	107	4.2e-27	89.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918596094	259	98.88	5	256	2	266	6.7e-51	167.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918596096	299	96.01	6	298	5	293	2.8e-66	218.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918596097	258	73.58	1	229	6	200	2.6e-43	142.5	COG0300	Short-chain dehydrogenase	265
2918596098	101	94.79	1	96	3	93	7.4e-12	39.8	COG5470	Uncharacterized conserved protein, DUF1330 family	96
2918596100	456	73.17	1	327	99	417	4.7e-70	229.9	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
2918596101	67	14.45	1	67	8	70	1.9e-06	21.2	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
2918596102	470	98.54	5	469	2	473	0.0e+00	506.6	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918596103	343	98.83	1	341	1	337	1.4e-110	363.8	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2918596104	305	97.34	10	305	2	294	4.7e-73	241	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918596105	147	56.15	1	144	58	162	1.2e-23	78.8	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918596107	208	97.12	3	208	6	207	1.0e-44	146.5	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918596108	359	97.37	138	358	4	225	3.6e-48	157.4	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918596110	238	92.11	2	237	5	249	8.5e-58	190.4	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
2918596114	715	98.2	29	532	6	497	0.0e+00	736.6	COG0753	Catalase	496
2918596118	69	98.51	1	69	1	66	5.4e-33	107.4	COG1278	Cold shock protein, CspA family	67
2918596120	269	87.57	1	267	12	307	1.9e-37	124	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2918596121	124	26.36	1	102	245	336	1.1e-36	120.7	COG5397	Uncharacterized protein	349
2918596122	138	60.19	1	133	64	190	1.7e-31	103.7	COG2085	Predicted dinucleotide-binding enzyme	211
2918596124	479	94.54	14	477	21	418	1.3e-82	272.7	COG0232	dGTP triphosphohydrolase	412
2918596127	205	54.88	57	119	6	50	1.4e-03	11.7	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
2918596131	735	48.59	93	505	133	270	1.2e-11	36.6	COG2801	Transposase InsO and inactivated derivatives	232
2918596132	329	83.94	25	288	38	267	1.8e-04	14.3	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
2918596134	155	22.05	5	52	7	34	3.4e-09	7.8	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2918596134	155	46.46	85	155	65	123	3.4e-09	22.1	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2918596136	432	93.33	24	432	13	376	8.9e-53	171.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918596137	239	97.35	6	234	2	221	9.8e-85	277.8	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918596138	402	99.8	17	402	2	510	1.4e-76	253.2	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918596142	129	95.45	3	111	5	109	2.1e-37	121.8	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2918596143	127	92.92	8	127	7	111	9.9e-42	135.7	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
2918596144	416	99.02	11	416	3	407	0.0e+00	544	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
2918596145	423	68.43	35	418	131	427	1.1e-68	226.5	COG0719	Fe-S cluster assembly scaffold protein SufB	412
2918596146	251	96.43	1	251	3	245	1.6e-105	346.3	COG0396	Fe-S cluster assembly ATPase SufC	251
2918596147	489	99.77	40	487	1	433	0.0e+00	526.3	COG0719	Fe-S cluster assembly scaffold protein SufB	412
2918596148	386	98.19	2	386	2	380	1.2e-126	417.2	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
2918596149	225	98.1	1	212	4	209	1.1e-95	313.3	COG2945	Alpha/beta superfamily hydrolase	210
2918596150	373	99.2	1	373	2	372	0.0e+00	437.1	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
2918596151	417	98.51	5	417	5	402	0.0e+00	470.5	COG0162	Tyrosyl-tRNA synthetase	401
2918596153	155	98.09	1	155	2	155	2.3e-63	207.1	COG1225	Peroxiredoxin	157
2918596154	275	98.88	6	275	3	267	1.0e-125	412.8	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
2918596155	432	94.94	79	431	8	307	1.4e-60	200.1	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2918596156	501	89.62	1	482	30	495	0.0e+00	524.7	COG0513	Superfamily II DNA and RNA helicase	513
2918596157	138	86.3	4	138	5	130	3.5e-30	99.4	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2918596158	374	93.99	28	371	11	354	1.6e-35	117.1	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918596159	225	97.27	3	222	4	217	1.6e-92	302.8	COG0036	Pentose-5-phosphate-3-epimerase	220
2918596161	435	99.54	1	434	1	437	0.0e+00	574.7	COG0015	Adenylosuccinate lyase	438
2918596162	187	98.34	4	184	3	180	1.0e-78	257.7	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
2918596163	254	94.91	1	249	8	268	1.2e-86	284.7	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
2918596164	80	93.98	1	80	2	79	2.0e-34	112.1	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
2918596165	223	97.95	1	222	3	241	8.3e-86	281.6	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
2918596167	98	93.65	21	92	2	60	1.1e-21	70.8	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918596168	472	98.46	11	465	2	450	2.3e-92	304.5	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918596169	744	97.36	2	729	16	752	0.0e+00	877.2	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
2918596170	77	93.33	1	77	2	85	1.5e-25	83.9	COG0271	Stress-induced morphogen (activity unknown)	90
2918596173	111	98.1	1	104	2	104	4.5e-49	159.1	COG0278	Glutaredoxin-related protein	105
2918596174	416	47.78	224	414	11	193	2.1e-30	10.3	COG0477	MFS family permease	338
2918596174	416	73.11	13	266	8	287	2.1e-30	91.4	COG0477	MFS family permease	338
2918596175	274	96.14	3	272	8	256	4.9e-59	194.1	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2918596176	275	93.44	3	272	10	251	3.3e-62	204.5	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2918596177	308	80.84	43	302	1	249	4.2e-71	233.8	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
2918596178	309	99.03	1	307	4	309	0.0e+00	436.9	COG2066	Glutaminase	309
2918596179	205	100	1	205	1	210	4.9e-62	203.8	COG0522	Ribosomal protein S4 or related protein	205
2918596180	327	97.66	59	327	2	251	3.5e-73	240.6	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918596181	514	96.83	27	513	4	523	4.0e-37	122.2	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
2918596182	295	96.01	1	289	8	296	3.8e-45	148.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918596183	212	97.6	1	208	1	203	1.2e-61	201.9	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918596186	273	94.4	9	273	6	258	3.3e-81	266.8	COG0796	Glutamate racemase	269
2918596187	280	98.39	11	265	2	245	2.2e-93	306.7	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
2918596189	404	96.57	1	399	15	408	0.0e+00	459.8	COG0538	Isocitrate dehydrogenase	407
2918596190	208	94.42	3	203	4	206	6.4e-40	131.7	COG0625	Glutathione S-transferase	211
2918596191	887	98.75	1	887	8	878	0.0e+00	1174.3	COG0013	Alanyl-tRNA synthetase	879
2918596192	350	98.28	1	280	6	291	3.0e-127	418	COG0468	RecA/RadA recombinase	279
2918596193	313	98.73	3	305	1	312	1.1e-48	160.2	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918596194	307	95.48	3	307	11	306	0.0e+00	510.7	COG2313	Pseudouridine-5'-phosphate glycosidase (pseudoU degradation)	310
2918596195	751	77.39	565	743	44	197	4.2e-33	109.9	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918596196	257	94.7	1	257	9	276	1.6e-69	228.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918596197	267	97.39	40	267	3	226	4.7e-87	285.5	COG4215	ABC-type arginine transport system, permease component	230
2918596198	276	99.12	48	276	2	227	3.4e-93	305.9	COG4160	ABC-type arginine/histidine transport system, permease component	228
2918596199	95	98.89	6	95	2	90	1.9e-52	170.1	COG5425	Usg protein (tryptophan operon, function unknown)	90
2918596200	274	98.61	1	274	4	286	6.2e-126	414	COG4976	Predicted methyltransferase, contains TPR repeat	287
2918596201	321	94.03	1	321	9	323	4.0e-76	250.9	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918596202	162	96.2	1	151	6	157	3.0e-44	145.2	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918596203	214	94.06	8	213	10	199	1.1e-55	182.5	COG1573	Uracil-DNA glycosylase	202
2918596204	197	91.24	1	180	12	188	1.1e-40	133.4	COG1525	Endonuclease YncB, thermonuclease family	192
2918596205	511	84.01	127	493	57	387	4.0e-68	224.9	COG0642	Signal transduction histidine kinase	336
2918596206	132	97.56	11	132	3	122	1.6e-36	119.3	COG0818	Diacylglycerol kinase	123
2918596207	344	96.86	9	344	2	340	1.1e-117	387.4	COG2038	NaMN:DMB phosphoribosyltransferase	347
2918596208	261	96.39	4	261	6	245	1.1e-69	229.3	COG0368	Cobalamin synthase	246
2918596209	40	48.65	1	40	29	64	3.7e-08	28.1	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
2918596210	235	100	19	234	1	215	2.6e-83	273.4	COG3577	Predicted aspartyl protease	215
2918596211	499	99.4	2	496	3	501	1.0e-126	418.1	COG1070	Sugar (pentulose or hexulose) kinase	502
2918596212	282	98.51	1	274	4	268	1.5e-79	261.5	COG1830	Fructose-bisphosphate aldolase class Ia, DhnA family	265
2918596213	574	99.63	5	560	1	535	0.0e+00	487.1	COG0578	Glycerol-3-phosphate dehydrogenase	532
2918596214	332	97.5	6	329	3	314	7.2e-93	305.4	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918596215	324	97.81	1	320	7	319	2.5e-97	320.1	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
2918596216	333	96.87	20	333	7	315	2.4e-91	300.3	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918596217	506	98.6	1	498	6	499	0.0e+00	634.5	COG1129	ABC-type sugar transport system, ATPase component	500
2918596218	337	97.55	1	335	6	324	2.5e-59	195.1	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918596220	120	25.05	1	120	4	120	2.7e-25	83.6	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918596221	294	99.26	5	291	2	271	5.5e-111	364.5	COG3741	N-formylglutamate amidohydrolase	272
2918596223	258	98.84	1	256	3	258	1.7e-72	238.3	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2918596224	313	97.73	10	313	3	303	9.2e-71	232.8	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918596226	160	95.21	1	140	8	146	1.9e-41	135.8	COG0071	Molecular chaperone IbpA, HSP20 family	146
2918596227	339	97.84	1	330	3	319	3.2e-111	366	COG0385	Predicted Na+-dependent transporter	319
2918596228	286	97.01	2	282	1	292	1.4e-53	177	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918596229	499	98.6	1	499	6	499	0.0e+00	716.5	COG0554	Glycerol kinase	499
2918596230	573	99.1	2	514	3	441	2.1e-80	266	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918596231	97	100	1	97	1	97	6.5e-53	171.7	COG5477	Predicted small integral membrane protein	97
2918596232	307	96.47	32	307	10	282	1.2e-73	242.4	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918596233	288	96.31	1	288	8	294	9.6e-68	223.2	COG1175	ABC-type sugar transport system, permease component	295
2918596234	356	99.14	1	349	1	347	4.5e-104	342.9	COG3839	ABC-type sugar transport system, ATPase component	338
2918596235	356	99.14	1	348	3	349	9.5e-98	322.1	COG3839	ABC-type sugar transport system, ATPase component	338
2918596236	507	91.06	1	505	11	499	0.0e+00	607	COG0578	Glycerol-3-phosphate dehydrogenase	532
2918596237	257	99.21	1	253	1	252	1.5e-83	274.7	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2918596238	492	95.49	231	483	3	235	2.0e-88	289.9	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2918596238	492	96.21	17	227	2	204	3.5e-55	180.4	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
2918596239	882	76.19	826	882	3	50	4.4e-08	26.6	COG2906	Bacterioferritin-associated ferredoxin	63
2918596239	882	94.69	1	696	43	809	0.0e+00	646.1	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918596241	111	98.13	1	104	2	106	5.1e-31	101.2	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2918596242	815	99.63	1	806	3	800	0.0e+00	1231.6	COG1251	NAD(P)H-nitrite reductase, large subunit	793
2918596243	265	98.01	2	263	3	248	9.9e-97	317.7	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918596244	297	97.29	35	297	4	254	5.5e-83	272.7	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918596245	430	97.91	10	368	5	332	2.0e-100	330.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918596246	431	91.04	6	357	29	333	1.5e-80	265.2	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918596247	195	99.48	1	194	1	193	6.5e-80	261.7	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
2918596248	221	94.4	1	221	9	227	2.6e-47	155.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918596249	418	96.9	8	416	8	414	3.2e-76	250.9	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
2918596250	255	99.21	1	252	1	250	2.0e-111	365.8	COG1540	Lactam utilization protein B (function unknown)	252
2918596251	269	99.62	3	266	1	264	0.0e+00	441.8	COG4336	Uncharacterized protein YcsI, UPF0317 family	265
2918596252	538	90.31	1	214	10	214	1.8e-72	234.7	COG2049	Allophanate hydrolase subunit 1	223
2918596252	538	93.35	230	534	2	296	1.7e-96	317.2	COG1984	Allophanate hydrolase subunit 2	314
2918596253	577	11.92	485	577	569	645	0.0e+00	66	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918596253	577	70.43	1	470	2	456	0.0e+00	716.7	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918596254	495	83.37	11	495	26	456	3.5e-44	141.4	COG0366	Glycosidase	505
2918596255	151	93.18	10	126	2	124	6.1e-26	85.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918596256	702	99.29	10	702	6	700	0.0e+00	817.2	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
2918596258	422	95.29	91	422	3	326	8.7e-63	206.7	COG0547	Anthranilate phosphoribosyltransferase	338
2918596259	399	96.12	6	399	12	383	0.0e+00	510.8	COG4292	Low temperature requirement protein LtrA (function unknown)	387
2918596261	425	43.22	40	174	47	97	2.4e-05	18.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918596264	337	90.15	74	332	4	241	7.4e-45	148.2	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918596265	358	98.48	72	347	3	262	2.2e-67	222.1	COG1192	Cellulose biosynthesis protein BcsQ	259
2918596266	461	97.9	2	461	2	468	0.0e+00	471.6	COG4529	Uncharacterized NAD(P)/FAD-binding protein YdhS	474
2918596267	131	91.91	2	129	11	135	2.7e-32	105.8	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918596268	362	98.38	1	357	6	370	6.6e-121	397.9	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
2918596269	492	98.99	1	492	1	490	0.0e+00	733	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
2918596270	189	97.42	1	187	4	192	1.4e-59	195.7	COG3758	Various environmental stresses-induced protein Ves (function unknown)	193
2918596271	557	98.75	1	557	3	556	0.0e+00	1028.4	COG2987	Urocanate hydratase	561
2918596272	266	97.43	1	266	7	271	7.3e-115	377.3	COG3741	N-formylglutamate amidohydrolase	272
2918596273	514	99.4	3	502	2	496	0.0e+00	719.4	COG2986	Histidine ammonia-lyase	498
2918596274	419	98.03	13	419	3	401	0.0e+00	449.3	COG1228	Imidazolonepropionase or related amidohydrolase	406
2918596275	448	98.58	1	438	3	420	2.7e-94	310.4	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918596276	241	97.91	2	236	5	238	1.2e-63	209.2	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918596277	351	81.72	45	350	2	296	2.5e-52	172.5	COG3177	Fic family protein	348
2918596278	299	78.39	1	281	78	360	2.8e-86	284.3	COG3177	Fic family protein	348
2918596279	343	40	94	232	102	233	8.7e-34	30.3	COG0666	Ankyrin repeat	235
2918596279	343	56.67	5	159	86	272	8.7e-34	60.1	COG0666	Ankyrin repeat	235
2918596279	343	56.97	230	339	76	263	8.7e-34	25.9	COG0666	Ankyrin repeat	235
2918596280	335	98.98	15	327	2	293	6.2e-41	135.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918596282	205	82.78	5	203	11	183	1.1e-17	59.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918596283	303	97.34	2	297	3	295	6.3e-57	188	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918596284	263	73.08	13	263	28	217	1.8e-32	107.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918596285	716	97.99	6	716	7	736	1.8e-116	384.5	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918596286	210	98.6	1	199	1	212	2.7e-36	119.9	COG0625	Glutathione S-transferase	211
2918596287	413	95.95	19	412	7	385	4.3e-86	283.2	COG2814	Predicted arabinose efflux permease, MFS family	394
2918596288	252	93.93	1	242	1	232	2.4e-74	244.3	COG3967	Short-chain dehydrogenase involved in D-alanine esterification of teichoic acids	245
2918596289	320	96.31	1	311	8	320	2.7e-95	313.4	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918596290	1061	99.7	2	1041	2	1012	0.0e+00	1169.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2918596291	396	97.18	1	372	9	387	1.5e-62	206.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918596294	435	98.05	101	432	3	303	2.7e-66	217.9	COG0492	Thioredoxin reductase	305
2918596295	115	24.51	1	100	5	67	5.4e-06	21.1	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2918596296	158	17.2	1	46	15	46	9.9e-11	4.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918596296	158	39.78	36	147	105	178	9.9e-11	30	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918596298	276	98.98	9	276	2	293	2.8e-41	136.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918596299	926	68.92	1	133	9	110	3.8e-30	96.6	COG3710	DNA-binding winged helix-turn-helix (wHTH) domain	148
2918596299	926	97.34	133	550	4	406	5.7e-80	262.6	COG3903	Predicted ATPase	414
2918596300	216	72.01	25	215	75	267	1.1e-36	121.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918596301	184	78.03	30	176	27	129	9.6e-25	81.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918596302	125	83.09	8	125	20	132	2.0e-41	135.6	COG3474	Cytochrome c2	135
2918596303	149	94.23	1	149	5	151	1.7e-62	204.2	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918596304	86	28.57	1	86	17	102	2.8e-28	93.6	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2918596305	240	59.14	4	238	109	286	5.0e-48	158.2	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2918596306	353	8.35	13	54	144	177	3.6e-24	2.8	COG0303	Molybdopterin biosynthesis enzyme	404
2918596306	353	38.33	113	339	192	347	3.6e-24	74.8	COG0303	Molybdopterin biosynthesis enzyme	404
2918596307	278	98.31	10	274	4	293	5.5e-31	102.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918596308	463	99.34	3	453	3	454	0.0e+00	431	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918596309	290	99.32	10	284	2	294	2.4e-38	126.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918596310	321	73.46	35	301	35	225	2.7e-26	87	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918596311	907	98.07	129	549	6	411	8.9e-64	210.2	COG3903	Predicted ATPase	414
2918596312	205	97.38	2	175	2	187	3.4e-44	145.3	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
2918596313	638	70.85	408	576	29	186	6.7e-26	86.1	COG1226	Voltage-gated potassium channel Kch	212
2918596313	638	97.75	1	403	7	397	2.0e-90	297.8	COG0475	Kef-type K+ transport system, membrane component KefB	397
2918596314	425	34.15	7	83	32	87	2.6e-35	14.1	COG2010	Cytochrome c, mono- and diheme variants	150
2918596314	425	57.93	299	425	64	158	2.6e-35	45.3	COG2010	Cytochrome c, mono- and diheme variants	150
2918596314	425	99.39	125	303	1	163	2.6e-35	58.8	COG2010	Cytochrome c, mono- and diheme variants	150
2918596315	522	95.04	10	516	5	368	4.7e-13	38.6	COG0477	MFS family permease	338
2918596316	370	93.18	22	370	16	343	1.9e-93	307.2	COG1566	Multidrug resistance efflux pump	352
2918596317	286	96.56	9	286	5	313	4.3e-75	240.4	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918596319	325	97.63	49	325	6	293	2.4e-51	169.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918596320	220	84.21	21	220	7	182	4.0e-22	74.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918596321	305	75.77	24	277	19	215	6.4e-27	89	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918596322	910	75.68	2	135	9	120	3.3e-29	94.9	COG3710	DNA-binding winged helix-turn-helix (wHTH) domain	148
2918596322	910	96.38	131	549	9	407	1.6e-69	229.1	COG3903	Predicted ATPase	414
2918596323	324	91.23	62	324	15	222	9.7e-31	101	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918596324	207	96.5	6	207	3	195	4.2e-53	174.7	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
2918596325	509	98.33	5	500	3	473	5.0e-65	214.1	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918596326	172	95.54	12	168	7	156	3.0e-39	129	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
2918596327	241	96.12	24	236	3	200	5.3e-21	69.2	COG1335	Nicotinamidase-related amidase	205
2918596328	229	96.25	1	223	1	231	2.3e-54	177.6	COG5446	Uncharacterized membrane protein, predicted cobalt tansporter CbtA	233
2918596330	134	73.91	2	127	16	117	3.5e-19	63.2	COG3439	Uncharacterized conserved protein, DUF302 family	137
2918596331	252	96.73	19	236	5	241	1.0e-20	66.4	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
2918596336	97	35.9	3	93	22	63	7.6e-07	20.3	COG2963	Transposase and inactivated derivatives	116
2918596337	299	98.34	6	299	2	297	3.3e-59	195.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918596338	281	90.81	6	266	5	261	3.8e-29	96.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918596340	219	92.98	1	219	13	224	1.1e-70	232.3	COG0765	ABC-type amino acid transport system, permease component	222
2918596341	258	99.17	5	252	2	241	5.4e-105	344.3	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918596342	417	97.42	1	417	5	382	4.0e-62	200.2	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918596343	584	97.3	1	571	4	543	0.0e+00	460.7	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918596344	961	92.11	1	482	36	467	5.1e-90	296.4	COG0277	FAD/FMN-containing dehydrogenase	459
2918596344	961	98.5	506	958	5	399	6.2e-55	180.7	COG0247	Fe-S oxidoreductase	388
2918596345	411	97.22	16	410	9	393	1.2e-122	404.1	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918596346	510	96.24	12	498	17	477	0.0e+00	468.5	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918596347	464	98.91	1	464	2	455	0.0e+00	682.1	COG5383	Uncharacterized metalloenzyme YdcJ, glyoxalase superfamily	295
2918596348	289	91.2	53	267	4	200	3.2e-57	187.7	COG3316	Transposase (or an inactivated derivative)	215
2918596349	267	98.76	13	263	2	240	5.8e-112	367.1	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918596350	215	92.11	1	215	16	225	9.2e-58	190	COG0765	ABC-type amino acid transport system, permease component	222
2918596351	219	91.67	2	218	14	222	1.5e-63	208.8	COG0765	ABC-type amino acid transport system, permease component	222
2918596352	282	96.11	6	277	5	276	2.1e-42	139.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918596354	433	74.43	73	394	62	355	2.3e-29	96.6	COG1921	Seryl-tRNA(Sec) selenium transferase	395
2918596356	501	98.75	22	501	3	475	0.0e+00	484.8	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918596357	297	100	2	284	1	286	2.7e-84	277.2	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918596358	306	97.67	2	301	2	295	8.8e-47	154.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918596360	245	83.39	1	245	44	294	2.8e-41	136.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918596361	253	99.63	1	252	1	267	1.1e-70	232.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918596362	279	97.12	2	244	7	242	6.1e-93	304.8	COG3959	Transketolase, N-terminal subunit	243
2918596363	345	97.76	30	343	8	312	2.2e-116	382.2	COG3958	Transketolase, C-terminal subunit	312
2918596364	252	73.49	1	252	77	320	3.1e-69	228.2	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918596365	176	82.49	5	175	16	161	9.8e-24	78	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918596366	419	97.89	46	419	2	372	4.0e-122	402.4	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918596367	496	98.6	1	495	4	497	0.0e+00	462.5	COG1129	ABC-type sugar transport system, ATPase component	500
2918596368	337	96.24	22	336	9	315	4.7e-82	269.7	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918596369	325	95.72	1	317	11	323	1.4e-57	189.4	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918596370	297	97.5	1	297	7	279	1.7e-96	317.5	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2918596371	343	99.08	5	328	3	325	3.5e-74	244.5	COG3547	Transposase	303
2918596372	234	92.59	3	216	7	206	5.2e-73	239.4	COG3316	Transposase (or an inactivated derivative)	215
2918596374	192	74.59	2	192	43	177	6.8e-11	36.2	COG5342	Invasion protein IalB, involved in pathogenesis	181
2918596375	590	56.04	115	589	342	777	3.8e-54	178.3	COG5295	Autotransporter adhesin	715
2918596376	221	79.58	2	215	49	274	6.4e-41	135	COG2801	Transposase InsO and inactivated derivatives	232
2918596377	103	78.63	1	99	1	92	4.9e-16	53.6	COG2963	Transposase and inactivated derivatives	116
2918596379	123	75	1	121	24	131	1.4e-13	45.3	COG4190	Predicted transcriptional regulator	144
2918596381	234	93.06	2	219	7	207	3.3e-76	249.9	COG3316	Transposase (or an inactivated derivative)	215
2918596382	439	95.18	3	433	4	437	7.9e-76	250	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918596383	300	99.32	1	299	1	290	1.4e-65	216.2	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
2918596384	39	12.81	1	30	175	200	7.8e-05	16.8	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
2918596385	253	83.28	2	252	44	287	3.3e-21	70.2	COG0842	ABC-type multidrug transport system, permease component	286
2918596386	308	99.67	1	306	1	305	9.1e-92	302.2	COG1131	ABC-type multidrug transport system, ATPase component	293
2918596387	273	97.3	5	273	4	255	8.1e-44	144.2	COG0730	Uncharacterized membrane protein YfcA	258
2918596388	427	96.33	109	427	12	300	2.6e-125	411.8	COG3921	Uncharacterized conserved protein	300
2918596389	604	15.29	37	295	78	142	8.7e-110	21.8	COG0840	Methyl-accepting chemotaxis protein	408
2918596389	604	77.88	264	592	94	424	8.7e-110	338.9	COG0840	Methyl-accepting chemotaxis protein	408
2918596391	438	97.25	8	437	10	434	0.0e+00	607.8	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
2918596392	465	19.73	369	460	263	334	4.4e-121	35.6	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918596392	465	96.71	2	365	10	362	4.4e-121	365	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918596393	116	57.3	3	116	4	109	5.3e-39	128.1	COG4461	Uncharacterized protein YPO0702	185
2918596394	333	80.45	4	333	68	392	2.0e-40	133.5	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918596395	145	73.8	1	135	23	160	1.8e-22	74	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918596396	611	97.75	1	611	10	574	0.0e+00	799.2	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918596397	313	87.2	17	288	30	281	5.2e-95	312.2	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2918596398	215	98.11	7	215	4	211	2.0e-69	228	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
2918596400	290	98.48	26	290	2	260	1.6e-129	425.5	COG3739	Uncharacterized membrane protein YoaT, DUF817 family	263
2918596403	141	100	1	116	1	116	3.2e-53	173.2	COG0203	Ribosomal protein L17	116
2918596404	336	99.37	9	327	2	318	4.8e-128	421.2	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
2918596405	129	100	1	129	1	130	1.5e-61	201	COG0100	Ribosomal protein S11	129
2918596406	122	100	1	122	1	121	3.4e-53	173.6	COG0099	Ribosomal protein S13	121
2918596407	196	99.46	1	192	1	184	3.3e-70	230.5	COG0563	Adenylate kinase or related kinase	178
2918596408	446	97.27	7	438	9	436	0.0e+00	515.1	COG0201	Preprotein translocase subunit SecY	436
2918596409	159	98.7	1	152	1	152	4.6e-47	154.5	COG0200	Ribosomal protein L15	152
2918596410	68	98.18	12	66	1	54	1.5e-22	73.5	COG1841	Ribosomal protein L30/L7E	55
2918596411	189	95.11	1	179	8	182	2.6e-74	243	COG0098	Ribosomal protein S5	181
2918596412	120	96.83	1	120	5	126	7.4e-43	140.5	COG0256	Ribosomal protein L18	125
2918596413	177	98.88	1	177	1	177	6.9e-68	222.2	COG0097	Ribosomal protein L6P/L9E	178
2918596414	132	100	1	132	1	133	7.2e-52	169.2	COG0096	Ribosomal protein S8	132
2918596415	101	100	41	101	1	61	1.5e-25	83.6	COG0199	Ribosomal protein S14	61
2918596416	184	98.33	6	184	3	179	3.1e-81	265.8	COG0094	Ribosomal protein L5	180
2918596417	102	98.15	1	101	2	107	1.4e-31	103.5	COG0198	Ribosomal protein L24	104
2918596418	122	100	1	122	1	123	1.5e-59	193.9	COG0093	Ribosomal protein L14	122
2918596419	78	86.21	1	78	7	81	1.1e-37	122.4	COG0186	Ribosomal protein S17	87
2918596420	66	97.06	1	66	1	66	1.5e-28	93.2	COG0255	Ribosomal protein L29	69
2918596421	137	93.29	1	137	2	140	3.4e-58	190.1	COG0197	Ribosomal protein L16/L10AE	146
2918596422	243	97.42	12	243	1	227	5.3e-99	324.7	COG0092	Ribosomal protein S3	233
2918596423	129	95.3	2	125	7	148	1.4e-42	139.6	COG0091	Ribosomal protein L22	120
2918596424	92	98.92	1	92	1	92	5.6e-41	132.9	COG0185	Ribosomal protein S19	93
2918596425	278	99.64	1	275	1	274	1.6e-123	405.9	COG0090	Ribosomal protein L2	275
2918596426	97	97.87	6	97	1	92	3.3e-35	115.1	COG0089	Ribosomal protein L23	94
2918596427	206	97.7	1	206	2	213	8.3e-75	245.3	COG0088	Ribosomal protein L4	214
2918596428	202	93.39	1	202	11	222	5.8e-73	239.8	COG0087	Ribosomal protein L3	218
2918596429	102	98.08	1	102	1	102	2.1e-48	157.3	COG0051	Ribosomal protein S10	104
2918596430	81	20.3	1	81	314	393	1.9e-40	133.3	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2918596431	78	26.82	1	77	8	77	1.0e-24	81.5	COG4544	Uncharacterized conserved protein	260
2918596432	328	99.4	1	324	1	329	3.8e-81	267.4	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918596434	304	98.34	7	303	4	299	1.1e-65	216.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918596435	277	91.04	1	250	5	248	7.5e-53	174.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918596436	101	89.9	2	98	3	91	1.7e-25	83.3	COG1359	Quinol monooxygenase YgiN	100
2918596437	221	70.9	1	217	7	196	1.0e-27	91.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918596438	153	99.32	18	150	2	146	2.0e-20	68.9	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918596439	294	96.68	4	294	2	292	1.2e-65	216.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918596441	542	98.73	1	538	1	543	0.0e+00	647.1	COG0459	Chaperonin GroEL (HSP60 family)	524
2918596442	104	98.96	1	96	1	95	2.6e-42	137.4	COG0234	Co-chaperonin GroES (HSP10)	96
2918596443	90	100	1	90	1	90	9.7e-50	161.4	COG5425	Usg protein (tryptophan operon, function unknown)	90
2918596445	318	97.01	4	302	3	294	5.0e-68	224.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918596446	319	100	1	319	1	331	9.7e-82	269.4	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918596447	328	82.67	6	310	5	338	1.9e-43	142.8	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918596454	123	43.08	16	121	1	56	4.3e-09	32	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918596455	1196	95.74	565	1196	29	658	3.1e-95	314.8	COG3468	Type V secretory pathway, adhesin AidA	644
2918596456	183	50.59	2	181	136	306	3.2e-33	110.2	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2918596457	357	94.44	1	355	13	352	8.5e-76	249.6	COG0628	Predicted PurR-regulated permease PerM	355
2918596462	131	99.17	1	119	2	120	2.3e-48	158.1	COG5499	Antitoxin component HigA of the HigAB toxin-antitoxin module, contains an N-terminal HTH domain	120
2918596463	98	98.98	1	98	1	97	2.0e-44	144.6	COG4680	mRNA-degrading endonuclease (mRNA interferase) HigB, toxic component of the HigAB toxin-antitoxin module	98
2918596465	321	83.92	2	312	35	321	3.5e-61	201.6	COG0668	Small-conductance mechanosensitive channel	316
2918596467	309	89.7	6	304	7	276	4.4e-36	118.4	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918596468	126	22.39	1	125	372	493	6.0e-44	145.2	COG0405	Gamma-glutamyltranspeptidase	539
2918596469	143	40.97	1	143	2	144	5.3e-65	213.9	COG5397	Uncharacterized protein	349
2918596470	31	7.87	1	31	1	31	1.7e-16	54.4	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2918596471	699	99.31	1	699	1	724	0.0e+00	968.7	COG0480	Translation elongation factor EF-G, a GTPase	697
2918596472	156	99.32	2	149	2	148	5.0e-68	221.9	COG0049	Ribosomal protein S7	148
2918596473	123	95.35	1	123	7	129	3.1e-62	202.4	COG0048	Ribosomal protein S12	129
2918596475	116	93.84	4	114	8	144	1.6e-14	47.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918596476	361	77.5	283	354	15	76	2.7e-12	39.8	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918596477	1402	3.95	891	960	420	451	0.0e+00	11.8	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2918596477	1402	6.78	1296	1396	698	752	0.0e+00	20.3	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2918596477	1402	99.63	12	850	3	810	0.0e+00	1012.5	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2918596478	1378	99.17	3	1366	8	1084	0.0e+00	1524.7	COG0085	DNA-directed RNA polymerase, beta subunit/140 kD subunit	1060
2918596479	125	98.4	1	125	3	125	4.5e-49	159.4	COG0222	Ribosomal protein L7/L12	124
2918596480	172	96.59	1	171	5	174	3.7e-54	176.2	COG0244	Ribosomal protein L10	175
2918596481	231	99.57	1	227	1	229	8.7e-99	322.9	COG0081	Ribosomal protein L1	228
2918596482	143	99.29	2	143	1	140	1.4e-60	196.6	COG0080	Ribosomal protein L11	141
2918596483	176	99.45	1	176	1	182	2.5e-69	226	COG0250	Transcription antitermination factor NusG	178
2918596484	66	79.45	1	60	15	72	2.1e-26	84.7	COG0690	Preprotein translocase subunit SecE	73
2918596486	297	94.08	1	296	2	303	5.2e-49	160.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918596487	81	20.3	1	81	314	393	7.8e-41	133.3	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2918596488	122	31.69	23	122	187	276	2.1e-22	73.1	COG2801	Transposase InsO and inactivated derivatives	232
2918596490	420	99.47	27	402	3	378	0.0e+00	483.2	COG4782	Esterase/lipase superfamily enzyme	377
2918596495	228	96.79	11	216	7	217	3.8e-19	62.1	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918596496	344	12.21	39	181	74	131	1.3e-50	37.7	COG5361	Uncharacterized conserved protein	458
2918596496	344	41.47	147	343	275	471	1.3e-50	127.5	COG5361	Uncharacterized conserved protein	458
2918596497	333	66.67	208	333	40	127	1.2e-21	69.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918596499	94	46.15	1	93	1	60	1.2e-10	35.8	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918596500	270	18.06	1	220	865	1073	3.3e-29	94.6	COG0587	DNA polymerase III, alpha subunit	1139
2918596504	115	88.8	2	115	3	113	2.5e-20	66.5	COG3293	Transposase	124
2918596505	129	96.8	3	128	1	121	1.1e-20	67.5	COG3293	Transposase	124
2918596508	151	32.23	3	149	64	190	1.6e-11	37.8	COG0642	Signal transduction histidine kinase	336
2918596509	124	26.65	1	104	245	337	5.0e-37	120.7	COG5397	Uncharacterized protein	349
2918596511	261	98.88	2	259	3	267	9.1e-72	235	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918596512	311	95	1	311	15	318	1.9e-103	339	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
2918596513	490	98.2	1	485	5	496	0.0e+00	528.9	COG0554	Glycerol kinase	499
2918596514	318	99.04	5	315	3	311	6.7e-122	399.1	COG3958	Transketolase, C-terminal subunit	312
2918596515	269	97.94	1	236	6	243	8.9e-99	322.8	COG3959	Transketolase, N-terminal subunit	243
2918596516	326	95.61	15	326	10	314	9.6e-105	343.1	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918596517	309	97.25	1	308	6	323	9.8e-78	254.4	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918596518	492	98.8	1	492	5	499	0.0e+00	612.3	COG1129	ABC-type sugar transport system, ATPase component	500
2918596519	262	99.25	12	260	2	267	6.9e-70	228.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918596520	39	12.81	1	30	175	200	3.3e-05	16.8	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
2918596521	194	59.51	1	194	31	224	2.1e-37	122.4	COG3547	Transposase	303
2918596522	991	36.2	1	129	18	135	0.0e+00	87.2	COG4644	Transposase and inactivated derivatives, TnpA family	323
2918596522	991	99.69	624	950	2	326	0.0e+00	447.4	COG4644	Transposase and inactivated derivatives, TnpA family	323
2918596523	438	96.92	1	429	12	389	4.8e-42	137.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918596524	571	96.03	2	571	9	565	0.0e+00	781.5	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2918596525	1037	18.93	1	104	271	376	2.7e-43	27.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918596525	1037	24.11	490	746	306	440	2.7e-43	52.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918596525	1037	32.68	735	1033	327	509	2.7e-43	22.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918596525	1037	34.29	106	339	265	456	2.7e-43	45.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918596525	1037	43.21	216	532	241	482	2.7e-43	28.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918596526	1510	12.32	1391	1500	395	463	1.2e-22	17.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918596526	1510	38.39	362	1092	273	487	1.2e-22	40.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918596526	1510	41.07	1084	1355	232	461	1.2e-22	40.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918596528	153	77.7	13	151	17	131	5.0e-29	94.3	COG2994	ACP:hemolysin acyltransferase (hemolysin-activating protein)	148
2918596530	192	17.61	9	136	88	112	6.1e-05	16.4	COG1569	Predicted nucleic acid-binding protein, contains PIN domain	142
2918596532	507	98.21	1	503	1	495	0.0e+00	669.4	COG3333	TctA family transporter	504
2918596533	158	67.44	8	114	33	119	4.7e-04	12.6	COG2149	Uncharacterized membrane protein YidH, DUF202 family	120
2918596534	321	97.81	2	321	6	317	1.2e-89	293.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918596535	413	98.5	3	398	7	401	7.9e-124	406.7	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918596536	310	64.65	6	289	2	268	3.4e-43	141	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918596537	434	99.77	1	430	1	435	0.0e+00	537.1	COG2851	Mg2+/citrate symporter	433
2918596538	133	87.23	2	133	15	137	3.4e-24	78.3	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918596539	236	28.46	158	229	176	245	1.3e-48	38	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918596539	236	58.54	10	156	2	145	1.3e-48	118.8	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918596540	234	61.77	1	234	2	224	1.1e-43	142.9	COG3177	Fic family protein	348
2918596541	670	10.3	409	455	219	252	9.9e-16	6.5	COG0666	Ankyrin repeat	235
2918596541	670	27.58	589	660	153	243	9.9e-16	11.7	COG0666	Ankyrin repeat	235
2918596541	670	38.79	255	349	107	234	9.9e-16	4.6	COG0666	Ankyrin repeat	235
2918596541	670	49.09	449	568	91	252	9.9e-16	24.9	COG0666	Ankyrin repeat	235
2918596544	233	10.07	175	215	218	247	4.0e-19	15.4	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918596544	233	40.94	1	175	25	146	4.0e-19	48.2	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918596546	109	16.61	6	109	5	100	1.1e-20	66.9	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2918596547	97	66.67	1	91	7	84	3.5e-08	26	COG2963	Transposase and inactivated derivatives	116
2918596548	78	20.86	5	78	2	69	6.2e-18	58.5	COG3547	Transposase	303
2918596549	463	96.95	5	438	6	386	3.1e-99	325.7	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2918596550	407	50.13	211	404	4	195	3.4e-35	31.5	COG0477	MFS family permease	338
2918596550	407	70.5	7	263	7	276	3.4e-35	90	COG0477	MFS family permease	338
2918596552	197	57.7	2	193	140	330	2.7e-45	148.2	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918596561	179	30.12	3	179	413	593	2.3e-13	42.5	COG0465	ATP-dependent Zn proteases	596
2918596562	253	92.08	38	232	1	186	2.9e-48	156.8	COG1182	FMN-dependent NADH-azoreductase	202
2918596563	252	78.79	127	252	21	124	5.8e-23	74	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918596564	214	98.08	2	209	3	206	7.4e-56	181.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918596566	239	80	12	229	47	254	2.2e-49	161.7	COG1484	DNA replication protein DnaC	254
2918596567	510	92.25	7	289	15	276	2.1e-26	85.8	COG4584	Transposase	278
2918596568	419	98.16	12	398	5	324	8.8e-32	101.4	COG3547	Transposase	303
2918596569	430	57.44	1	351	227	558	1.7e-117	386.4	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2918596571	143	40.97	1	143	2	144	1.2e-65	214.8	COG5397	Uncharacterized protein	349
2918596573	174	60.78	1	174	9	180	1.8e-43	142.3	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918596574	85	27.52	1	85	212	293	3.1e-17	56.2	COG1175	ABC-type sugar transport system, permease component	295
