gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
2918249483	83	74.29	7	67	12	63	9.8e-06	20	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2918249484	291	78.07	6	290	17	315	3.3e-92	304.3	COG5534	Plasmid replication initiator protein	383
2918249485	212	20.08	1	62	3	55	2.5e-44	75.1	COG1192	Cellulose biosynthesis protein BcsQ	259
2918249485	212	54.17	59	211	114	256	2.5e-44	70.2	COG1192	Cellulose biosynthesis protein BcsQ	259
2918249487	217	65.53	1	212	3	175	3.6e-22	63.7	COG1192	Cellulose biosynthesis protein BcsQ	259
2918249490	494	71.1	1	486	137	564	1.7e-61	203.2	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
2918249492	345	81.49	8	331	52	346	1.1e-49	163.8	COG4962	Pilus assembly protein, ATPase of CpaF family	355
2918249494	110	56.19	14	108	15	73	1.4e-04	16.9	COG3702	Type IV secretory pathway, VirB3 components	105
2918249495	823	18.38	6	173	16	162	1.5e-54	29.5	COG3451	Type IV secretory pathway, VirB4 component	796
2918249495	823	57.38	309	812	305	763	1.5e-54	147.4	COG3451	Type IV secretory pathway, VirB4 component	796
2918249496	301	49.6	107	297	109	233	2.5e-07	24.9	COG5314	Conjugal transfer/entry exclusion protein	252
2918249498	437	72.47	2	380	37	365	6.6e-31	102.1	COG3846	Type IV secretory pathway, TrbL components	452
2918249500	319	64.84	37	316	26	202	4.0e-14	47.3	COG3504	Type IV secretory pathway, VirB9 components	265
2918249502	354	96.79	8	354	8	339	4.6e-111	365.7	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
2918249503	295	67.97	12	146	34	137	9.6e-17	55.4	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
2918249503	295	97.44	156	272	3	116	2.9e-38	125.2	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2918249504	169	94.59	5	145	3	142	5.3e-26	86.2	COG0394	Protein-tyrosine-phosphatase	139
2918249505	131	77.97	1	97	15	106	2.8e-12	41.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918249506	138	67.15	27	131	8	99	5.4e-29	95.2	COG1695	DNA-binding transcriptional regulator, PadR family	138
2918249508	414	88.61	20	410	36	385	1.9e-02	7	COG2814	Predicted arabinose efflux permease, MFS family	394
2918249509	299	80	1	58	11	66	9.6e-04	13.3	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2918249509	299	94.62	74	297	2	212	6.9e-42	137.8	COG1910	Periplasmic molybdate-binding protein/domain	223
2918249510	68	98.55	1	68	1	68	8.2e-29	94.5	COG3585	Molybdopterin-binding protein	69
2918249511	256	94.01	1	250	13	263	4.8e-51	168.2	COG0725	ABC-type molybdate transport system, periplasmic component	258
2918249512	265	44.02	2	129	143	256	1.6e-24	35.6	COG0730	Uncharacterized membrane protein YfcA	258
2918249512	265	45.17	138	265	5	121	1.6e-24	52.1	COG0730	Uncharacterized membrane protein YfcA	258
2918249513	225	96	2	224	2	217	5.3e-77	252.9	COG4149	ABC-type molybdate transport system, permease component	225
2918249514	356	98.3	3	356	5	350	3.1e-125	412.6	COG4148	ABC-type molybdate transport system, ATPase component	352
2918249516	175	96.53	1	168	3	169	5.0e-30	99.5	COG1495	Disulfide bond formation protein DsbB	170
2918249517	192	81.64	2	192	39	207	1.1e-62	206	COG2941	Demethoxyubiquinone hydroxylase, CLK1/Coq7/Cat5 family	204
2918249518	176	99.35	11	157	1	154	7.9e-33	108.2	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2918249520	285	56.04	1	283	10	278	3.1e-89	294.9	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2918249521	286	71.51	92	281	18	140	2.6e-05	18.4	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918249522	145	91.73	16	144	6	127	4.7e-30	98.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918249523	648	99.54	5	648	2	648	0.0e+00	939.7	COG2766	Predicted Ser/Thr protein kinase	649
2918249524	430	99.06	1	430	3	422	0.0e+00	499.2	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
2918249525	517	96.98	5	515	6	486	0.0e+00	650	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
2918249526	155	19.39	32	155	93	181	4.2e-12	39.6	COG4564	Signal transduction histidine kinase	459
2918249527	158	97.45	4	158	3	155	7.6e-66	215.5	COG1225	Peroxiredoxin	157
2918249528	999	92.11	5	936	32	918	0.0e+00	897.6	COG1391	Glutamine synthetase adenylyltransferase	963
2918249530	418	98.76	5	418	5	403	0.0e+00	462.5	COG0162	Tyrosyl-tRNA synthetase	401
2918249531	256	97.66	1	256	1	250	2.3e-86	284.3	COG0121	Predicted glutamine amidotransferase	252
2918249532	207	99.5	1	204	1	201	1.9e-69	227.9	COG1182	FMN-dependent NADH-azoreductase	202
2918249534	403	97.87	23	394	5	371	2.5e-90	297.8	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2918249536	69	94.2	1	69	1	65	4.0e-30	98.4	COG5554	Nitrogen fixation protein	69
2918249537	383	97.93	1	383	1	378	5.6e-126	415.3	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
2918249542	63	54.03	1	63	37	103	1.6e-09	32.4	COG1145	Ferredoxin	99
2918249543	519	93.02	49	452	2	334	6.1e-61	201	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2918249544	296	75	1	175	52	234	7.5e-35	114.9	COG2114	Adenylate cyclase, class 3	227
2918249545	633	95.82	2	633	23	549	0.0e+00	568.8	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2918249547	321	87.32	2	301	30	277	6.3e-91	298.9	COG3770	Murein endopeptidase	284
2918249548	313	41.26	83	308	64	181	2.1e-11	37.4	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2918249554	388	99.5	1	388	1	395	1.2e-54	180.3	COG0754	Glutathionylspermidine synthase	387
2918249556	206	97.41	2	197	4	191	4.6e-74	243.4	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
2918249557	418	65.27	126	418	110	404	4.1e-52	171.9	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
2918249558	391	99.75	1	391	1	393	0.0e+00	498.3	COG0183	Acetyl-CoA acetyltransferase	392
2918249559	240	97.76	1	238	6	267	3.3e-68	224.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918249560	160	95.42	1	160	2	147	4.4e-29	96.5	COG0716	Flavodoxin	151
2918249562	416	49.87	222	415	4	194	8.9e-19	32	COG0477	MFS family permease	338
2918249562	416	51.7	11	223	10	207	8.9e-19	37	COG0477	MFS family permease	338
2918249563	308	98.34	1	302	1	296	2.6e-52	173.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918249564	152	90.41	9	151	6	137	9.7e-27	88.4	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2918249565	282	96.89	24	279	6	254	5.9e-86	282.2	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918249566	366	100	1	366	1	372	0.0e+00	489.8	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
2918249567	190	97.88	1	187	2	186	1.9e-70	231	COG0193	Peptidyl-tRNA hydrolase	190
2918249568	199	96.77	5	97	4	93	9.1e-30	97.1	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
2918249569	120	25.32	29	59	6	25	5.9e-01	5.1	COG4238	Outer membrane murein-binding lipoprotein Lpp	78
2918249569	120	29.11	2	32	8	30	5.9e-01	4.3	COG4238	Outer membrane murein-binding lipoprotein Lpp	78
2918249570	312	98.11	1	312	6	317	2.7e-122	402.7	COG0462	Phosphoribosylpyrophosphate synthetase	314
2918249571	144	88.89	1	137	2	129	1.3e-15	52.2	COG2703	Hemerythrin	144
2918249572	255	96.41	3	255	9	250	8.4e-77	252.5	COG1496	Copper oxidase (laccase) domain	249
2918249573	392	94.32	13	377	10	358	3.1e-106	349.9	COG1565	SAM-dependent methyltransferase, MidA family	370
2918249574	270	93.06	1	267	6	273	2.5e-92	303.5	COG0682	Prolipoprotein diacylglyceryltransferase	287
2918249575	328	98.75	1	325	2	318	8.6e-63	207.5	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918249576	568	97.34	41	478	1	402	1.1e-130	431	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918249577	243	97.39	15	243	5	228	1.7e-76	251.2	COG1346	Putative effector of murein hydrolase	230
2918249578	119	89.06	1	118	7	120	2.6e-33	109	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
2918249579	267	21.2	8	88	12	57	1.5e-31	10.8	COG5637	Uncharacterized membrane protein	217
2918249579	267	65.9	93	249	72	214	1.5e-31	92.2	COG5637	Uncharacterized membrane protein	217
2918249580	393	99.72	1	391	2	353	3.1e-101	333.3	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918249582	568	88.71	160	563	45	421	5.4e-59	195.4	COG0840	Methyl-accepting chemotaxis protein	408
2918249583	674	85.47	8	558	23	563	0.0e+00	442.1	COG0296	1,4-alpha-glucan branching enzyme	628
2918249584	679	93.19	19	676	4	605	2.2e-109	361.1	COG3408	Glycogen debranching enzyme (alpha-1,6-glucosidase)	641
2918249587	534	73.51	255	506	66	262	1.9e-45	149.8	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918249589	391	57.57	21	390	229	559	4.8e-84	277.9	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
2918249590	174	85.95	2	174	24	182	5.9e-56	184.1	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
2918249591	221	83.85	4	154	2	110	5.4e-18	60.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918249594	149	97.26	5	149	2	143	1.9e-65	213.6	COG0757	3-dehydroquinate dehydratase	146
2918249595	151	98.64	11	151	2	146	2.8e-39	130	COG0511	Biotin carboxyl carrier protein	140
2918249596	446	68.73	1	446	1	444	0.0e+00	661.6	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918249597	486	83.76	35	486	60	389	2.5e-59	196.6	COG0642	Signal transduction histidine kinase	336
2918249598	227	99.57	3	227	1	231	4.1e-83	273	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918249599	527	26.85	413	527	260	357	5.2e-126	25.9	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918249599	527	95.34	16	419	14	361	5.2e-126	395.5	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918249600	139	97.81	1	138	3	136	8.8e-47	153.2	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
2918249601	155	99.32	1	147	1	145	1.6e-32	107.1	COG3427	Carbon monoxide dehydrogenase subunit G	146
2918249604	134	56.87	11	134	1	120	3.7e-28	93.3	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918249605	828	78.12	193	718	78	409	7.4e-52	169.3	COG0840	Methyl-accepting chemotaxis protein	408
2918249606	607	100	1	607	1	615	0.0e+00	765.8	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
2918249607	450	99.13	4	443	3	457	0.0e+00	536.2	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
2918249608	231	97.3	4	224	5	220	7.5e-58	190.8	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918249613	300	98.25	20	299	3	282	2.0e-105	346.6	COG0414	Panthothenate synthetase	285
2918249614	153	84.91	5	153	24	158	1.7e-09	32.3	COG1580	Flagellar basal body-associated protein FliL	159
2918249615	446	95.74	1	430	19	445	0.0e+00	729	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
2918249617	322	31.42	68	162	205	308	1.1e-47	54.6	COG0790	TPR repeat	292
2918249617	322	60.12	113	291	123	321	1.1e-47	116.9	COG0790	TPR repeat	292
2918249618	447	49.87	249	446	5	195	7.3e-15	13.1	COG0477	MFS family permease	338
2918249618	447	72.58	14	277	3	280	7.3e-15	41.3	COG0477	MFS family permease	338
2918249619	302	98.92	1	290	1	275	9.6e-94	308.5	COG3546	Mn-containing catalase (includes spore coat protein CotJC)	277
2918249620	455	99.56	2	446	2	454	0.0e+00	482.3	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918249621	164	93.71	6	164	8	156	3.4e-09	31.2	COG1580	Flagellar basal body-associated protein FliL	159
2918249622	382	83.17	19	381	17	357	1.3e-26	86.5	COG1488	Nicotinic acid phosphoribosyltransferase	405
2918249623	110	84.38	51	109	3	56	2.1e-20	67.2	COG3411	(2Fe-2S) ferredoxin	64
2918249624	438	28.83	336	438	236	331	4.9e-45	43.8	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918249624	438	42.04	135	340	54	193	4.9e-45	108.7	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918249625	326	97.97	6	300	3	291	2.4e-117	385.8	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
2918249629	370	98.96	4	370	2	382	4.0e-118	389.3	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
2918249630	124	93.13	1	123	9	130	7.1e-48	156.4	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
2918249631	451	97.12	1	451	11	448	0.0e+00	480.6	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
2918249632	522	97.99	31	522	5	491	0.0e+00	613.5	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2918249633	383	23.63	48	224	97	152	7.8e-05	16	COG0412	Dienelactone hydrolase	236
2918249637	469	99.1	2	469	4	445	0.0e+00	582.9	COG0174	Glutamine synthetase	443
2918249638	112	100	1	112	1	112	7.8e-50	162.9	COG0347	Nitrogen regulatory protein PII	112
2918249640	485	96.88	208	483	9	287	3.7e-81	266.5	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
2918249640	485	99.02	1	193	2	204	3.1e-54	177	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
2918249643	444	99.33	1	441	1	445	5.8e-127	418.9	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
2918249644	209	95.5	8	206	3	193	8.4e-91	297.8	COG0740	ATP-dependent protease ClpP, protease subunit	200
2918249645	420	98.53	16	419	1	403	0.0e+00	673.9	COG1219	ATP-dependent protease Clp, ATPase subunit	408
2918249646	664	83.53	182	657	67	421	8.4e-56	182.5	COG0840	Methyl-accepting chemotaxis protein	408
2918249647	808	97.96	3	782	10	777	0.0e+00	1160.8	COG0466	ATP-dependent Lon protease, bacterial type	782
2918249648	90	95.74	1	90	2	91	1.1e-35	116.6	COG0776	Bacterial nucleoid DNA-binding protein	94
2918249651	218	81.25	1	217	10	217	2.5e-52	172.4	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918249652	248	91.56	2	150	8	148	2.8e-18	60.9	COG3133	Outer membrane lipoprotein SlyB	154
2918249653	162	87.23	8	148	16	138	6.5e-27	88.7	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918249654	154	97.97	1	149	1	145	4.2e-62	203.1	COG0102	Ribosomal protein L13	148
2918249655	162	96.99	31	162	5	133	2.9e-54	177.6	COG0103	Ribosomal protein S9	130
2918249656	358	99.71	14	358	2	349	2.1e-120	396.7	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
2918249657	172	93.22	3	172	6	170	6.2e-60	196.3	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2918249658	203	55.28	43	197	85	194	8.0e-31	102.5	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918249659	216	95.78	20	193	3	161	2.6e-34	113.4	COG3467	Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily	166
2918249660	522	98.46	24	496	2	450	0.0e+00	440.6	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918249662	97	36.65	1	92	105	185	1.6e-03	12.8	COG4649	Uncharacterized protein	221
2918249663	1105	86.93	667	1105	53	451	3.0e-93	307.6	COG3281	Predicted trehalose synthase	438
2918249663	1105	99.81	13	524	1	516	5.8e-125	413	COG0366	Glycosidase	505
2918249664	751	99.68	118	748	2	632	0.0e+00	891.7	COG0296	1,4-alpha-glucan branching enzyme	628
2918249665	769	77.99	188	696	60	346	3.1e-12	41	COG0457	Tetratricopeptide (TPR) repeat	291
2918249667	712	98.01	2	710	8	697	0.0e+00	910	COG1523	Pullulanase/glycogen debranching enzyme	697
2918249668	351	52.16	10	181	4	124	1.0e-10	35.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918249669	745	96.79	181	740	11	522	0.0e+00	498.8	COG1640	4-alpha-glucanotransferase	520
2918249672	251	98.02	2	251	2	248	8.1e-86	282.2	COG0149	Triosephosphate isomerase	251
2918249673	111	86.02	1	100	1	80	3.7e-26	85.6	COG1314	Preprotein translocase subunit SecG	86
2918249674	543	99.25	2	542	2	532	0.0e+00	810.3	COG0504	CTP synthase (UTP-ammonia lyase)	533
2918249675	606	90.67	2	333	11	350	9.4e-62	201.3	COG3240	Phospholipase/lecithinase/hemolysin	370
2918249675	606	94.14	367	606	2	226	5.6e-31	102.6	COG5571	Uncharacterized protein YhjY, contains autotransporter beta-barrel domain	239
2918249676	231	98.31	1	231	4	236	9.7e-53	173.8	COG0412	Dienelactone hydrolase	236
2918249677	275	96.77	2	275	3	272	0.0e+00	443.9	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
2918249678	155	96.83	30	155	3	124	2.4e-42	138.4	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
2918249679	547	67.05	47	330	53	288	8.0e-43	140	COG1566	Multidrug resistance efflux pump	352
2918249680	220	90.71	1	208	18	222	1.6e-81	267.6	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918249681	410	99.8	18	410	2	510	8.1e-75	247.7	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918249687	274	96.69	1	266	7	269	1.0e-86	285.3	COG3741	N-formylglutamate amidohydrolase	272
2918249688	157	56.02	23	145	47	139	4.3e-06	21.6	COG3495	Uncharacterized protein	166
2918249689	386	85.15	8	374	44	324	3.9e-64	211.1	COG3608	Predicted deacylase	331
2918249691	407	96.82	2	392	2	397	2.0e-15	52.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918249693	277	32.03	1	269	2	116	6.2e-15	51.1	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918249694	155	63.85	27	147	2	84	3.2e-19	64.5	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918249695	271	47.28	19	220	23	170	4.7e-06	20.5	COG1216	Glycosyltransferase, GT2 family	305
2918249696	1003	21.29	888	977	129	181	4.3e-50	20.2	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918249696	1003	21.69	666	755	133	186	4.3e-50	19.9	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918249696	1003	27.71	229	424	120	188	4.3e-50	20.6	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918249696	1003	28.92	746	870	130	201	4.3e-50	32.5	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918249696	1003	81.12	36	244	11	212	4.3e-50	85.9	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918249697	343	90.49	4	343	3	316	1.4e-96	318.2	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2918249699	299	97.84	8	292	2	273	1.2e-79	262	COG0388	Predicted amidohydrolase	274
2918249700	187	93.23	33	160	4	127	3.3e-23	76.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918249701	438	24.3	365	431	121	181	9.4e-97	52.3	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918249701	438	36.65	17	117	109	200	9.4e-97	85.3	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918249701	438	42.63	245	365	104	210	9.4e-97	80.8	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918249701	438	54.18	110	251	73	208	9.4e-97	118	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918249702	240	93.06	2	235	11	238	1.4e-58	192.8	COG0704	Phosphate uptake regulator	240
2918249703	431	95.1	9	360	15	344	5.9e-117	385.3	COG2951	Membrane-bound lytic murein transglycosylase B	343
2918249705	161	88.27	6	148	17	159	6.0e-16	53.7	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918249707	434	96.34	3	434	13	433	0.0e+00	532.8	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
2918249710	332	99.08	12	332	2	325	1.8e-98	324.1	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918249711	238	94.54	52	235	5	177	2.2e-48	159	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918249712	135	90.98	14	135	6	126	2.2e-35	116.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918249713	464	98.85	15	458	1	430	0.0e+00	458.9	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918249714	1187	33.06	682	896	31	191	2.0e-16	36.7	COG1061	Superfamily II DNA or RNA helicase	442
2918249714	1187	45.59	899	1168	187	408	2.0e-16	15.7	COG1061	Superfamily II DNA or RNA helicase	442
2918249715	228	63.36	6	183	64	210	4.5e-10	34.5	COG0671	Membrane-associated phospholipid phosphatase	232
2918249716	302	79.55	171	298	23	127	6.0e-28	91.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918249717	234	91.63	4	234	10	228	1.8e-61	202.4	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
2918249718	100	96	4	100	3	98	7.3e-21	69.1	COG4541	Uncharacterized membrane protein	100
2918249721	881	62.57	368	757	26	341	6.2e-47	154.9	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2918249721	881	95.41	7	302	15	305	4.8e-54	177.8	COG5309	Exo-beta-1,3-glucanase,  GH17 family	305
2918249722	575	95.18	1	445	7	440	1.6e-66	219.2	COG2233	Xanthine/uracil permease	451
2918249723	379	80.73	20	339	48	311	2.8e-38	126.5	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2918249725	715	98.94	19	681	3	658	0.0e+00	1073.9	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
2918249727	871	68.32	365	737	50	394	6.9e-57	187.7	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2918249727	871	92.13	1	292	21	301	3.2e-57	188.5	COG5309	Exo-beta-1,3-glucanase,  GH17 family	305
2918249728	137	82.98	5	133	24	140	5.9e-24	79.3	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2918249730	355	98.3	5	354	5	351	1.3e-106	351.5	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918249731	340	99.67	40	340	2	301	5.3e-73	240.7	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918249732	557	96.51	18	555	14	538	1.5e-130	430.8	COG1178	ABC-type Fe3+ transport system, permease component	540
2918249733	608	99.34	1	605	3	601	0.0e+00	969.3	COG1217	Predicted membrane GTPase involved in stress response	603
2918249734	632	94.86	46	632	32	603	3.5e-95	314.2	COG0729	Outer membrane translocation and assembly module TamA	594
2918249735	1430	98.73	1	1430	18	1334	0.0e+00	540.5	COG2911	Autotransporter translocation and assembly factor TamB	1278
2918249736	281	65.59	8	261	22	204	5.1e-17	57.3	COG0500	SAM-dependent methyltransferase	257
2918249737	103	54.35	8	96	11	85	4.8e-04	14.7	COG3105	Uncharacterized membrane-anchored protein YhcB, DUF1043 family	138
2918249739	319	49.5	41	291	136	285	1.7e-36	120.8	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2918249740	188	87.1	21	184	19	180	5.1e-50	164.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918249741	54	98.15	1	54	1	53	5.7e-25	82.1	COG5487	Uncharacterized membrane protein YtjA, UPF0391 family	54
2918249744	174	77.78	93	173	6	75	2.4e-15	27	COG3830	ACT domain, binds amino acids and other small ligands	90
2918249744	174	85.56	2	85	4	80	2.4e-15	22.9	COG3830	ACT domain, binds amino acids and other small ligands	90
2918249745	477	96.93	19	475	14	455	0.0e+00	480.2	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2918249746	449	95.75	11	448	12	417	4.8e-121	398.9	COG4949	Uncharacterized membrane-anchored protein	424
2918249747	287	97.24	6	285	4	250	2.2e-75	247.7	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2918249748	536	89.98	18	536	7	518	0.0e+00	768.1	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2918249749	299	92.51	4	296	19	302	3.3e-114	376	COG0109	Polyprenyltransferase (heme O synthase)	304
2918249751	203	91.63	1	194	13	198	2.6e-75	247	COG3175	Cytochrome c oxidase assembly protein Cox11	195
2918249752	291	96.71	69	285	6	211	8.3e-67	219.2	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918249753	106	82.54	1	106	20	123	7.5e-41	133.7	COG5349	Uncharacterized conserved protein, DUF983 family	126
2918249754	256	93.7	1	249	6	243	1.1e-71	235.7	COG3346	Cytochrome oxidase assembly protein ShyY1	252
2918249755	496	98.99	1	496	5	496	0.0e+00	564.6	COG2317	Zn-dependent carboxypeptidase, M32 family	497
2918249756	442	88.89	2	371	28	403	2.9e-50	166.3	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
2918249757	469	99.28	1	461	2	417	0.0e+00	437	COG0498	Threonine synthase	411
2918249758	418	96.11	1	412	17	436	7.4e-113	372.2	COG0612	Predicted Zn-dependent peptidase	438
2918249759	203	91.44	11	203	14	184	4.2e-45	148.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918249761	91	29.05	18	85	71	122	2.8e-03	13.2	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
2918249762	439	47.04	1	439	141	267	5.9e-36	116.3	COG1360	Flagellar motor protein MotB	244
2918249764	252	60.3	72	235	53	172	1.3e-08	29.8	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918249765	273	95.37	4	259	4	250	1.3e-83	274.9	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2918249766	188	98.47	1	130	3	131	2.6e-44	144.7	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
2918249767	260	16.43	3	96	369	460	4.8e-26	35.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918249767	260	35	63	254	319	514	4.8e-26	64.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918249768	354	97.83	4	352	6	320	5.8e-104	342.5	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
2918249769	444	98.42	8	444	8	444	1.1e-103	341.9	COG2067	Long-chain fatty acid transport protein	440
2918249770	268	97.3	3	253	3	254	7.6e-56	183.9	COG0730	Uncharacterized membrane protein YfcA	258
2918249771	250	96.68	10	220	5	208	7.3e-62	202.8	COG0352	Thiamine monophosphate synthase	211
2918249772	309	95.91	14	309	5	262	1.4e-59	196.3	COG1830	Fructose-bisphosphate aldolase class Ia, DhnA family	265
2918249775	115	94.59	1	108	3	107	2.5e-27	90.1	COG4226	Predicted nuclease of the RNAse H fold, HicB family	111
2918249776	786	18.11	147	320	22	134	4.5e-91	9.9	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918249776	786	57.21	420	785	264	620	4.5e-91	286.7	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918249777	752	16.85	506	723	54	100	1.9e-03	9.3	COG0500	SAM-dependent methyltransferase	257
2918249777	752	77.17	5	348	63	346	2.7e-19	63.7	COG0457	Tetratricopeptide (TPR) repeat	291
2918249778	555	81.18	25	550	79	423	3.0e-60	195.5	COG0840	Methyl-accepting chemotaxis protein	408
2918249779	335	98.81	2	335	2	332	0.0e+00	483.4	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
2918249780	665	98.94	6	665	5	660	0.0e+00	933.2	COG0021	Transketolase	663
2918249781	74	11.22	1	73	229	284	1.2e-04	15.7	COG4372	Uncharacterized conserved protein, contains DUF3084 domain	499
2918249782	104	64.76	1	104	1	68	1.7e-16	55	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
2918249784	192	96.86	4	191	5	189	4.4e-40	132.5	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
2918249785	274	99.25	1	270	1	264	3.1e-99	326.3	COG1692	Calcineurin-like phosphoesterase	266
2918249787	250	99.59	1	243	1	242	1.1e-93	307.9	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
2918249788	351	85.27	200	323	15	124	1.2e-40	132.2	COG2852	Very-short-patch-repair endonuclease	129
2918249788	351	95.03	12	171	1	153	1.5e-58	191.4	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
2918249789	207	99.5	1	206	1	200	9.8e-51	166.8	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
2918249790	358	94.88	9	338	16	330	0.0e+00	489.6	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
2918249791	170	96.4	11	155	4	137	1.3e-39	129.8	COG0824	Acyl-CoA thioesterase FadM	137
2918249792	243	99.07	25	240	2	215	1.3e-67	222.7	COG0811	Biopolymer transport protein ExbB/TolQ	216
2918249793	159	92.81	6	144	7	135	1.7e-43	142.6	COG0848	Biopolymer transport protein ExbD	137
2918249795	450	96.5	17	449	15	428	9.7e-128	421.5	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2918249796	155	56.28	7	155	84	195	9.7e-43	141.5	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918249797	286	92.8	3	281	18	262	4.8e-50	165.6	COG1729	Periplasmic TolA-binding protein (function unknown)	262
2918249798	452	64.94	13	252	11	210	2.0e-53	175.9	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
2918249799	644	99	9	604	2	596	0.0e+00	889.6	COG0465	ATP-dependent Zn proteases	596
2918249801	282	98.07	5	265	3	256	3.0e-120	395	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
2918249802	446	90.76	12	305	17	291	6.2e-55	180.9	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2918249803	314	37.66	1	165	2	146	7.6e-78	132.6	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2918249803	314	37.92	158	313	218	363	7.6e-78	125.6	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2918249804	155	97.79	10	153	2	134	1.2e-31	104.4	COG4520	Surface antigen	136
2918249805	203	90.19	1	203	22	214	2.2e-86	283.5	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
2918249806	309	94.1	1	299	8	294	1.4e-89	295	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2918249807	463	43.93	157	282	54	158	1.4e-03	5.4	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2918249807	463	44.35	10	146	51	156	1.4e-03	8.4	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2918249807	463	57.32	47	213	16	152	1.4e-03	7.2	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2918249808	274	93.04	1	270	4	257	3.1e-43	142.7	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2918249809	411	99.06	3	406	3	422	7.7e-62	204	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
2918249810	412	61.65	163	410	119	335	1.3e-70	232.3	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2918249811	394	96.63	14	385	1	315	9.1e-91	294.1	COG0523	GTPase, G3E family	323
2918249812	166	95.86	16	166	5	143	1.0e-38	127.1	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2918249813	484	99.14	4	480	3	461	0.0e+00	529.8	COG0415	Deoxyribodipyrimidine photolyase	461
2918249814	242	81.59	21	235	7	201	6.4e-46	151.1	COG1407	Metallophosphoesterase superfamily enzyme	235
2918249815	839	97.92	10	833	9	855	0.0e+00	770.9	COG1201	Lhr-like helicase	814
2918249816	79	50	1	71	31	81	9.9e-09	29.7	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918249817	136	95.42	1	133	3	127	1.3e-25	85	COG5455	Periplasmic regulator RcnB of Ni and Co efflux	129
2918249818	231	86.38	1	228	20	241	4.5e-56	183.5	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918249819	788	99.33	1	770	5	744	0.0e+00	652.2	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918249820	241	88.5	3	222	24	223	2.2e-69	227.8	COG2135	Putative SOS response-associated peptidase YedK	226
2918249821	186	74.74	5	186	45	189	2.1e-25	83.8	COG1525	Endonuclease YncB, thermonuclease family	192
2918249822	265	12.9	2	64	23	46	1.9e-10	8.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918249822	265	31.72	49	147	121	179	1.9e-10	29	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918249822	265	91.73	138	261	6	127	4.5e-13	43.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918249823	85	97.56	1	82	1	80	1.8e-22	74	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
2918249824	217	96.36	1	217	2	213	2.1e-91	299.7	COG0036	Pentose-5-phosphate-3-epimerase	220
2918249825	265	97.38	6	262	7	266	2.6e-69	228.1	COG0725	ABC-type molybdate transport system, periplasmic component	258
2918249826	231	97.78	4	229	2	221	2.1e-78	257.6	COG4149	ABC-type molybdate transport system, permease component	225
2918249827	370	99.72	1	357	1	351	0.0e+00	431.2	COG4148	ABC-type molybdate transport system, ATPase component	352
2918249829	129	78.81	11	116	22	114	2.2e-20	67.2	COG2919	Cell division protein FtsB	117
2918249830	339	92.46	2	339	14	344	0.0e+00	445.4	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
2918249831	462	99.38	139	462	2	323	0.0e+00	471.8	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
2918249832	444	99.77	1	444	1	433	0.0e+00	475.7	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2918249833	100	85.15	1	92	8	93	4.6e-20	66.5	COG1605	Chorismate mutase	101
2918249834	465	99.56	2	455	2	454	0.0e+00	559.6	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918249836	318	98.37	3	308	4	304	0.0e+00	462.1	COG0320	Lipoate synthase	306
2918249837	151	98.63	1	145	1	144	1.1e-53	175.5	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
2918249838	434	32.67	21	117	101	182	5.3e-75	58.6	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918249838	434	46.22	120	239	70	185	5.3e-75	85.2	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918249838	434	64.14	245	420	87	247	5.3e-75	114.7	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918249839	387	98.19	2	385	7	386	0.0e+00	527.7	COG3146	Predicted N-acyltransferase	387
2918249840	155	96.32	8	155	4	134	5.9e-23	76	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918249841	621	70.1	316	621	116	387	6.1e-23	32.1	COG1344	Flagellin and related hook-associated protein FlgL	360
2918249841	621	78.35	5	337	13	316	6.1e-23	52.7	COG1344	Flagellin and related hook-associated protein FlgL	360
2918249842	520	87.03	28	512	45	480	8.2e-76	250.3	COG2939	Carboxypeptidase C (cathepsin A)	498
2918249843	568	87.29	76	562	53	423	9.3e-60	195.5	COG0840	Methyl-accepting chemotaxis protein	408
2918249844	159	88.89	10	145	3	130	1.8e-26	87.3	COG2703	Hemerythrin	144
2918249845	488	81.47	78	469	56	376	3.7e-59	195.7	COG0642	Signal transduction histidine kinase	336
2918249846	221	99.14	1	221	1	230	2.6e-72	237.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918249847	367	99.34	65	367	1	299	7.8e-62	204	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918249848	555	97.61	1	555	10	540	0.0e+00	432.9	COG1178	ABC-type Fe3+ transport system, permease component	540
2918249849	358	87.82	1	337	6	315	2.1e-103	340.9	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918249850	558	87.76	44	556	49	421	8.0e-54	176.9	COG0840	Methyl-accepting chemotaxis protein	408
2918249851	228	96.06	9	215	6	200	2.5e-44	146.2	COG0461	Orotate phosphoribosyltransferase	201
2918249852	347	99.69	17	347	2	325	1.8e-117	386.6	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
2918249853	675	43.55	540	647	40	93	2.1e-29	18.2	COG1145	Ferredoxin	99
2918249853	675	64.52	235	344	30	109	2.1e-29	38.3	COG1145	Ferredoxin	99
2918249853	675	69.35	301	574	38	123	2.1e-29	65.1	COG1145	Ferredoxin	99
2918249855	282	90.36	4	281	22	274	1.8e-101	333.3	COG2998	ABC-type tungstate transport system, permease component	280
2918249856	231	98.24	2	228	4	226	9.0e-67	219.4	COG4662	ABC-type tungstate transport system, periplasmic component	227
2918249857	293	92.88	12	270	19	266	4.3e-61	201.1	COG1526	Formate dehydrogenase assembly factor FdhD	266
2918249858	207	98.45	1	201	2	192	1.3e-51	169.6	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
2918249859	232	89.29	5	222	7	206	3.4e-53	175.1	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2918249860	651	84.26	37	620	56	387	1.4e-55	183.2	COG0642	Signal transduction histidine kinase	336
2918249861	271	97.03	1	254	8	268	4.3e-76	250.6	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
2918249862	159	93.79	1	157	9	159	2.1e-26	87.2	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2918249863	216	96.27	57	215	3	157	1.3e-28	94.2	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2918249864	74	90	1	74	7	78	7.0e-21	69	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
2918249865	247	97.62	1	247	7	252	2.9e-64	211.7	COG0356	FoF1-type ATP synthase, membrane subunit a	246
2918249866	121	59.48	2	119	36	104	9.4e-20	65.3	COG5336	FoF1-type ATP synthase assembly protein I	116
2918249867	204	95.71	1	203	4	204	1.4e-60	199.1	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
2918249868	711	83.06	119	555	72	424	2.6e-58	192.2	COG0840	Methyl-accepting chemotaxis protein	408
2918249868	711	88.89	578	711	3	130	5.1e-29	95	COG2703	Hemerythrin	144
2918249869	246	62.65	6	246	111	323	7.8e-96	316	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
2918249870	251	98.69	14	250	3	228	1.4e-54	179.9	COG0850	Septum formation inhibitor MinC	219
2918249871	271	98.53	1	271	2	269	1.6e-127	419.1	COG2894	Septum formation inhibitor-activating ATPase MinD	272
2918249872	127	96.59	1	88	1	85	5.0e-31	101.1	COG0851	Septum formation topological specificity factor MinE	88
2918249875	436	81.41	2	430	78	423	9.4e-54	172.3	COG0840	Methyl-accepting chemotaxis protein	408
2918249877	330	94.1	1	330	5	355	2.1e-59	196	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918249878	137	87.13	18	115	10	97	4.1e-26	85.6	COG2154	Pterin-4a-carbinolamine dehydratase	101
2918249879	207	30.69	7	99	38	99	1.4e-29	57	COG1573	Uracil-DNA glycosylase	202
2918249879	207	42.57	118	207	114	199	1.4e-29	39.1	COG1573	Uracil-DNA glycosylase	202
2918249880	345	94.86	1	344	10	378	5.1e-43	142.1	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918249881	695	99.57	1	695	3	690	0.0e+00	814	COG0751	Glycyl-tRNA synthetase, beta subunit	691
2918249882	293	93.96	10	293	5	284	0.0e+00	517.9	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
2918249887	430	92.52	27	414	10	380	6.6e-76	249.9	COG1944	Ribosomal protein S12 methylthiotransferase accessory factor YcaO	398
2918249888	464	95.06	1	242	3	233	7.7e-70	229.2	COG3482	Uncharacterized protein	237
2918249889	92	98.81	3	92	2	84	4.1e-06	22.2	COG1977	Molybdopterin converting factor, small subunit	84
2918249890	385	86.84	14	118	13	111	4.2e-20	65.6	COG0607	Rhodanese-related sulfurtransferase	110
2918249890	385	97.7	119	373	3	257	3.1e-83	273.3	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
2918249891	131	92.48	2	131	8	130	7.7e-29	95	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918249892	583	75.89	142	576	92	390	4.2e-49	162.5	COG0642	Signal transduction histidine kinase	336
2918249893	544	69.04	219	544	117	388	1.8e-41	138	COG0642	Signal transduction histidine kinase	336
2918249893	544	95.49	1	167	5	131	3.1e-26	82.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918249894	906	73.86	505	902	101	391	4.4e-75	248.5	COG0642	Signal transduction histidine kinase	336
2918249894	906	95.8	4	543	11	489	1.3e-77	255.9	COG0591	Na+/proline symporter	493
2918249896	754	48.35	39	296	99	215	5.4e-08	26.7	COG2202	PAS domain	232
2918249896	754	75.2	541	753	18	208	7.8e-47	154.6	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2918249897	133	50.86	3	130	2	119	2.2e-40	133.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918249898	342	71.85	163	341	65	235	5.8e-13	44.3	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
2918249899	99	54.26	1	92	1	51	3.9e-20	67	COG1826	Sec-independent protein translocase protein TatA	94
2918249900	188	96.67	5	183	2	175	3.7e-59	194.8	COG2917	Intracellular septation protein A	180
2918249903	503	99.58	211	482	1	236	3.2e-59	194.7	COG0775	Nucleoside phosphorylase	234
2918249904	468	87.78	57	464	44	359	2.5e-118	390.2	COG0552	Signal recognition particle GTPase	340
2918249905	427	97.96	15	427	6	437	2.0e-126	417.1	COG0621	tRNA A37 methylthiotransferase MiaB	437
2918249906	278	99.26	3	273	2	270	6.7e-93	305.7	COG0253	Diaminopimelate epimerase	272
2918249907	147	90.65	16	147	11	136	7.0e-15	48.6	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
2918249908	334	49.58	19	254	3	180	3.4e-15	51.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918249910	203	96.89	1	203	1	187	1.2e-81	267.9	COG0066	3-isopropylmalate dehydratase small subunit	191
2918249911	372	98.85	3	369	3	346	4.8e-123	405.1	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2918249912	80	50	1	42	26	62	1.0e-22	34.5	COG3729	General stress protein YciG, contains tandem KGG domains	73
2918249912	80	74.32	16	76	18	72	1.0e-22	51.6	COG3729	General stress protein YciG, contains tandem KGG domains	73
2918249913	293	98.6	10	290	1	281	1.3e-88	291.7	COG2301	Citrate lyase beta subunit	283
2918249914	592	27.45	3	103	243	343	6.2e-17	34.1	COG0457	Tetratricopeptide (TPR) repeat	291
2918249914	592	59.78	68	403	51	270	6.2e-17	34.1	COG0457	Tetratricopeptide (TPR) repeat	291
2918249915	286	99.64	2	286	1	280	1.6e-95	314.3	COG2240	Pyridoxal/pyridoxine/pyridoxamine kinase	281
2918249916	730	68.53	262	719	120	389	3.1e-75	249	COG0642	Signal transduction histidine kinase	336
2918249917	389	96.51	1	388	13	371	7.6e-130	428	COG1485	Predicted ATPase	367
2918249918	84	41.54	2	83	3	56	1.1e-05	21.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918249927	444	92.24	89	426	20	328	4.8e-22	73.5	COG0582	Integrase	309
2918249928	303	68.74	1	295	134	432	1.1e-79	262.8	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918249929	1012	99.3	53	945	3	710	7.0e-71	234.3	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2918249930	449	98.61	3	448	4	429	1.3e-122	404.2	COG0124	Histidyl-tRNA synthetase	429
2918249931	170	63.86	75	143	3	55	3.9e-03	11.7	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
2918249932	351	99.13	2	348	3	343	0.0e+00	494.1	COG0418	Dihydroorotase	344
2918249933	539	39.1	339	518	267	440	0.0e+00	70.4	COG1570	Exonuclease VII, large subunit	440
2918249933	539	76.63	28	376	4	344	0.0e+00	431.6	COG1570	Exonuclease VII, large subunit	440
2918249934	428	98.83	1	428	1	424	0.0e+00	544.4	COG0151	Phosphoribosylamine-glycine ligase	428
2918249935	152	92.81	2	150	11	152	6.5e-50	163.9	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2918249936	69	97.18	1	69	1	69	2.2e-29	96.7	COG3360	Flavin-binding protein dodecin	71
2918249937	457	94.72	16	251	3	235	1.0e-71	235.5	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2918249938	185	97.87	1	183	2	185	1.5e-50	166.1	COG0742	16S rRNA G966 N2-methylase RsmD	187
2918249939	449	50.65	225	443	8	201	1.2e-20	25.7	COG0477	MFS family permease	338
2918249939	449	65.54	19	281	14	264	1.2e-20	45.4	COG0477	MFS family permease	338
2918249941	553	98.26	10	512	1	508	2.1e-104	345.4	COG0366	Glycosidase	505
2918249942	328	97.34	1	310	6	298	1.1e-33	111.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918249943	201	84.09	75	199	16	126	6.6e-25	81.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918249944	411	93.13	87	393	18	329	4.9e-36	119.3	COG0582	Integrase	309
2918249946	92	44.62	5	88	7	64	8.0e-08	28.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918249951	223	45.45	29	152	9	68	1.1e-05	19.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918249958	135	19.2	3	135	8	131	4.0e-21	69.8	COG5525	Phage terminase, large subunit GpA	611
2918249961	350	83.88	14	333	33	313	6.2e-23	76.5	COG0582	Integrase	309
2918249963	517	90.96	1	489	30	502	0.0e+00	491.5	COG0513	Superfamily II DNA and RNA helicase	513
2918249964	181	27.18	3	60	3	58	3.4e-19	14	COG1335	Nicotinamidase-related amidase	205
2918249964	181	42.72	57	165	111	198	3.4e-19	48.6	COG1335	Nicotinamidase-related amidase	205
2918249965	233	91.86	2	233	23	293	1.7e-30	101.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918249967	662	99.69	10	660	3	641	0.0e+00	769.8	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
2918249968	141	74.52	13	141	14	130	4.1e-43	141.4	COG1607	Acyl-CoA hydrolase	157
2918249969	141	87.79	1	125	3	117	1.8e-38	126.2	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
2918249970	388	97.68	27	337	6	300	3.1e-70	231.2	COG0031	Cysteine synthase	300
2918249971	561	81.18	167	556	79	423	3.4e-51	165.2	COG0840	Methyl-accepting chemotaxis protein	408
2918249974	227	96.55	23	225	3	198	2.6e-79	260.1	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
2918249975	222	96.92	10	213	4	192	2.3e-74	243.8	COG0194	Guanylate kinase	191
2918249976	288	98.62	1	288	5	290	3.9e-87	287.3	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
2918249977	253	96.23	1	253	7	261	3.3e-48	158.9	COG0300	Short-chain dehydrogenase	265
2918249978	429	57.98	238	423	87	235	3.8e-05	16	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918249979	396	99.45	4	366	1	360	1.4e-121	400.8	COG0349	Ribonuclease D	361
2918249980	605	99.49	4	595	1	583	0.0e+00	755	COG0173	Aspartyl-tRNA synthetase	585
2918249983	260	94.92	1	259	6	248	3.5e-102	335.4	COG0052	Ribosomal protein S2	252
2918249984	310	99.33	1	308	1	295	3.5e-111	365.8	COG0264	Translation elongation factor EF-Ts	296
2918249985	259	99.16	21	256	2	237	9.0e-97	318	COG0528	Uridylate kinase	238
2918249986	185	95.72	3	185	9	187	2.8e-72	236.8	COG0233	Ribosome recycling factor	187
2918249987	251	92.46	2	245	19	251	5.8e-96	315.4	COG0020	Undecaprenyl pyrophosphate synthase	245
2918249988	293	98.55	33	289	2	272	1.1e-60	200.4	COG0575	CDP-diglyceride synthetase	265
2918249989	399	98.19	9	393	2	380	0.0e+00	500.3	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
2918249990	378	98.76	8	368	3	399	5.1e-89	294	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
2918249991	773	98.71	14	773	11	774	0.0e+00	742	COG4775	Outer membrane protein assembly factor BamA	766
2918249992	219	90.59	40	208	16	169	2.3e-22	74.1	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
2918249993	160	96.62	14	160	4	146	2.2e-51	168.3	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2918249994	264	98.08	1	259	4	258	4.1e-110	361.8	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
2918249995	283	97.85	2	275	5	277	1.0e-85	282.1	COG3494	Uncharacterized conserved protein, DUF1009 family	279
2918249996	397	98.95	3	385	3	378	2.3e-126	416.3	COG0763	Lipid A disaccharide synthetase	381
2918249997	131	99.32	4	129	2	146	1.5e-26	89.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918249999	321	95.38	2	321	12	321	8.1e-98	322	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918250000	135	87.72	23	132	12	111	4.7e-18	60	COG0607	Rhodanese-related sulfurtransferase	110
2918250002	437	99.75	33	436	2	396	0.0e+00	551.4	COG0372	Citrate synthase	390
2918250003	468	97.5	1	466	9	476	0.0e+00	509.5	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2918250004	722	93.47	47	597	26	469	4.7e-56	185.5	COG0658	Predicted membrane metal-binding protein	453
2918250005	238	98.52	1	238	3	202	4.6e-69	226.8	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2918250006	409	98.03	1	405	6	404	1.6e-129	426.6	COG0303	Molybdopterin biosynthesis enzyme	404
2918250007	165	98.08	1	158	2	154	1.6e-66	217.7	COG0315	Molybdenum cofactor biosynthesis enzyme	157
2918250008	152	85.8	2	140	19	157	4.3e-13	44.5	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918250009	264	99.61	5	262	1	253	1.9e-96	316.9	COG0134	Indole-3-glycerol phosphate synthase	254
2918250010	350	99.12	10	346	3	339	0.0e+00	433.4	COG0547	Anthranilate phosphoribosyltransferase	338
2918250011	197	98.43	1	189	3	190	1.1e-75	248.1	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
2918250012	639	45.38	5	174	196	362	8.0e-24	34.9	COG0457	Tetratricopeptide (TPR) repeat	291
2918250012	639	60.05	133	342	136	356	8.0e-24	53.1	COG0457	Tetratricopeptide (TPR) repeat	291
2918250013	393	86.67	154	391	29	249	1.1e-70	231.9	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
2918250014	67	91.78	1	66	2	68	3.1e-10	35	COG2608	Copper chaperone CopZ	71
2918250015	76	58.54	1	73	8	55	1.3e-06	23.2	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
2918250016	503	98.5	21	501	3	462	0.0e+00	546.5	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2918250017	627	9.85	434	555	85	116	7.0e-18	2.3	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918250017	627	96	8	404	4	315	7.0e-18	58.5	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918250018	589	71.59	5	423	4	386	1.0e-85	280.9	COG1283	Na+/phosphate symporter	533
2918250019	60	86.57	1	60	4	61	1.0e-20	68.4	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2918250021	114	94.5	6	114	6	108	8.8e-43	139.6	COG1742	Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily	109
2918250024	720	65.46	210	712	217	650	6.9e-93	306.2	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918250025	627	98.61	1	595	3	568	0.0e+00	669.9	COG3263	NhaP-type Na+/H+ and K+/H+ antiporter with C-terminal TrkAC and CorC domains	574
2918250026	159	95.59	14	159	5	134	2.1e-28	93.7	COG4520	Surface antigen	136
2918250027	63	27.92	7	63	64	106	2.9e-01	5.7	COG3133	Outer membrane lipoprotein SlyB	154
2918250028	331	92.48	8	325	7	301	5.3e-71	234.2	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2918250029	601	98.99	21	593	6	591	0.0e+00	572.5	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918250030	261	96.34	1	261	4	266	6.8e-51	167.7	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2918250031	259	99.22	1	256	2	256	3.6e-90	296.4	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
2918250032	516	97.32	2	516	5	548	0.0e+00	630.7	COG0143	Methionyl-tRNA synthetase	558
2918250034	213	98.08	4	211	2	205	1.7e-68	225.1	COG0125	Thymidylate kinase	208
2918250035	387	94.4	1	384	14	384	2.9e-112	370.3	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2918250036	320	60.48	16	215	61	210	3.2e-64	211.6	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
2918250037	271	96.54	24	263	6	228	8.7e-39	128.1	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
2918250038	652	90.12	147	648	41	423	6.9e-60	198.3	COG0840	Methyl-accepting chemotaxis protein	408
2918250039	158	95.54	6	156	4	153	6.1e-49	160.7	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
2918250042	116	96.33	3	116	5	109	3.5e-24	80	COG3784	Uncharacterized conserved protein YdbL, DUF1318 family	109
2918250043	669	84.94	107	658	92	621	0.0e+00	446.6	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918250045	196	80.87	2	179	6	153	1.0e-48	159.7	COG0241	Histidinol phosphatase or a related phosphatase	181
2918250046	763	93.59	13	756	31	775	4.2e-104	344	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
2918250047	473	97.92	2	473	10	480	0.0e+00	633.6	COG5310	Homospermidine synthase	481
2918250048	427	95.44	25	409	18	394	5.1e-69	227.4	COG0019	Diaminopimelate decarboxylase	394
2918250049	185	96.13	1	182	1	174	3.2e-51	168	COG1791	Acireductone dioxygenase (methionine salvage), cupin superfamily	181
2918250050	400	94.43	12	400	11	383	1.4e-34	113.9	COG2814	Predicted arabinose efflux permease, MFS family	394
2918250051	421	99.3	1	421	1	428	0.0e+00	593.9	COG0172	Seryl-tRNA synthetase	429
2918250052	261	97.66	11	260	2	251	3.0e-84	277.1	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
2918250053	218	94.79	5	216	5	204	1.2e-68	225.4	COG2518	Protein-L-isoaspartate O-methyltransferase	209
2918250054	451	15.19	55	105	3	50	6.7e-52	7.2	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2918250054	451	95.89	103	446	2	304	6.7e-52	163	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2918250055	285	97.23	1	285	6	286	2.7e-119	392.2	COG2607	Predicted ATPase, AAA+ superfamily	287
2918250056	141	93.81	12	109	4	94	1.2e-33	109.6	COG1862	Preprotein translocase subunit YajC	97
2918250057	532	98.66	1	532	1	516	0.0e+00	593.6	COG0342	Preprotein translocase subunit SecD	506
2918250058	316	98.05	4	311	3	304	8.4e-101	331.8	COG0341	Preprotein translocase subunit SecF	305
2918250059	125	88.98	4	124	14	126	4.9e-36	118.5	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
2918250060	197	97.07	1	197	2	200	2.0e-71	234.9	COG0605	Superoxide dismutase	204
2918250061	421	11.27	102	304	230	285	1.4e-17	9	COG1233	Phytoene dehydrogenase-related protein	487
2918250061	421	19.11	10	112	6	100	1.4e-17	49.6	COG1233	Phytoene dehydrogenase-related protein	487
2918250062	297	94.12	6	291	10	281	1.6e-64	212.6	COG1562	Phytoene/squalene synthetase	288
2918250063	294	91.35	24	292	20	283	1.1e-38	127.9	COG1562	Phytoene/squalene synthetase	288
2918250064	284	93.08	1	282	4	272	2.9e-39	129.8	COG1562	Phytoene/squalene synthetase	288
2918250065	447	98.41	3	447	4	435	0.0e+00	681.8	COG1206	Folate-dependent tRNA-U54 methylase TrmFO/GidA	439
2918250066	76	8.8	3	61	8	46	1.3e-03	13.1	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918250067	950	99.68	1	942	3	940	0.0e+00	1486.3	COG0178	Excinuclease UvrABC ATPase subunit	935
2918250068	525	93.53	19	509	3	421	1.7e-61	203.1	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
2918250069	172	96.93	1	170	1	158	1.3e-39	130.3	COG2062	Phosphohistidine phosphatase SixA	163
2918250070	715	98.43	8	700	6	693	0.0e+00	933	COG0855	Polyphosphate kinase	696
2918250071	515	91.31	23	503	4	455	1.7e-101	334.9	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
2918250072	404	61.62	11	160	5	118	5.8e-11	36.4	COG4461	Uncharacterized protein YPO0702	185
2918250074	269	52.46	1	266	232	487	2.3e-78	259.1	COG3956	Uncharacterized conserved protein YabN, contains tetrapyrrole methylase and MazG-like pyrophosphatase domain	488
2918250075	484	99.06	43	484	4	423	1.5e-68	226	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
2918250076	308	90.98	10	192	3	123	1.6e-22	74.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918250077	126	66.67	3	123	35	138	3.3e-18	60.4	COG4729	Uncharacterized protein	156
2918250078	697	96.65	7	694	19	652	0.0e+00	712.9	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
2918250079	312	96.27	3	312	10	319	1.6e-102	337.4	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
2918250080	166	96.15	3	157	3	152	1.6e-68	223.7	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918250081	795	99.33	2	787	4	743	0.0e+00	756.5	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918250082	263	98.25	1	263	1	281	2.0e-72	238.9	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2918250083	309	75.45	4	302	22	270	1.1e-66	219.7	COG0714	MoxR-like ATPase	329
2918250084	407	97.73	1	392	7	394	7.4e-126	414.9	COG3552	Uncharacterized conserved protein, contains von Willebrand factor type A (vWA) domain	395
2918250085	109	33.55	8	109	2	102	3.6e-32	106.6	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2918250086	238	47.18	4	237	144	285	7.9e-49	161.1	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2918250087	546	8.35	16	56	144	177	2.7e-32	11	COG0303	Molybdopterin biosynthesis enzyme	404
2918250087	546	70.02	53	359	65	349	2.7e-32	96.3	COG0303	Molybdopterin biosynthesis enzyme	404
2918250087	546	96	341	538	2	193	5.6e-58	189.9	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
2918250088	236	97.47	4	202	1	193	6.3e-41	134.8	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2918250089	141	53.97	1	138	101	229	1.3e-32	107.8	COG1186	Protein chain release factor B	239
2918250090	297	97.69	34	293	4	257	7.9e-82	269	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
2918250092	287	94.92	17	287	11	290	1.5e-33	111.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918250095	755	90.23	357	755	7	126	1.1e-13	45.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918250095	755	97.46	2	234	6	235	9.5e-62	202.6	COG3300	MHYT domain, NO-binding membrane sensor	236
2918250096	803	96.15	3	790	10	758	0.0e+00	578.7	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
2918250097	404	97.69	1	335	6	343	4.6e-105	346.2	COG1171	Threonine dehydratase	347
2918250098	260	93.63	17	258	3	237	1.1e-85	281.6	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918250099	250	96.12	1	250	7	254	1.6e-56	186.3	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918250100	343	97.31	1	343	4	329	2.3e-42	140.2	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918250101	623	96.45	417	610	2	191	3.0e-76	248.7	COG0529	Adenylylsulfate kinase or related kinase	197
2918250101	623	98.16	2	430	5	430	2.6e-127	419.5	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
2918250102	265	92.16	2	265	21	267	7.7e-54	177.4	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2918250103	240	80.97	4	236	32	248	4.9e-50	164.8	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2918250104	185	78.67	1	181	3	168	2.4e-32	106.8	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
2918250105	273	96.72	12	260	3	238	1.2e-86	284.9	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2918250107	563	99.61	12	559	1	512	0.0e+00	567.7	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2918250108	166	93.41	2	163	10	165	1.0e-42	140.2	COG3749	Uncharacterized conserved protein, DUF934 family	167
2918250109	273	52.83	148	273	73	156	9.5e-14	31.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918250109	273	96.23	1	143	4	156	9.5e-14	18.3	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918250111	206	90.53	19	205	10	181	3.9e-62	203.8	COG3703	Cation transport regulator ChaC	190
2918250112	341	30.77	222	339	231	334	3.7e-13	13	COG4093	Uncharacterized protein	338
2918250112	341	32.25	3	161	13	121	3.7e-13	29.6	COG4093	Uncharacterized protein	338
2918250115	255	95.31	1	250	1	244	1.3e-61	202.9	COG0121	Predicted glutamine amidotransferase	252
2918250116	404	81.98	7	403	66	388	2.6e-70	232.5	COG0642	Signal transduction histidine kinase	336
2918250117	149	100	1	147	1	144	2.3e-39	129.4	COG2927	DNA polymerase III, chi subunit	144
2918250118	502	96.92	3	501	14	485	0.0e+00	546.2	COG0260	Leucyl aminopeptidase	485
2918250119	468	91.9	97	435	29	357	2.0e-91	301.6	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
2918250120	373	19.26	10	155	62	134	1.6e-91	19.9	COG2821	Membrane-bound lytic murein transglycosylase	373
2918250120	373	65.17	126	370	129	375	1.6e-91	287.9	COG2821	Membrane-bound lytic murein transglycosylase	373
2918250121	177	82.72	5	171	22	155	1.7e-08	29.7	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918250122	254	19.01	8	68	2	51	1.9e-28	12.3	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2918250122	254	53.23	100	251	116	255	1.9e-28	80.2	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2918250123	492	87.16	1	215	8	197	2.4e-117	166.9	COG0516	IMP dehydrogenase/GMP reductase	170
2918250123	492	94.5	262	481	12	217	2.4e-117	223.4	COG0516	IMP dehydrogenase/GMP reductase	170
2918250124	235	98.54	26	232	1	202	1.4e-76	251.4	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
2918250125	341	62.02	22	341	3	309	2.1e-95	314.9	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
2918250126	403	95.36	16	378	4	352	3.6e-39	129.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918250128	448	79.88	6	443	27	435	3.1e-91	301.1	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
2918250129	342	99.43	1	341	1	347	0.0e+00	454.3	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
2918250130	419	97.04	6	375	1	361	0.0e+00	541.6	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
2918250131	154	87.25	3	147	17	146	7.4e-52	169.6	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
2918250132	353	99.71	13	350	2	341	1.9e-127	419.8	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
2918250133	391	84.58	51	391	59	387	4.6e-36	118	COG4552	Predicted acetyltransferase	389
2918250134	799	90.82	326	794	38	423	3.7e-60	199.2	COG0840	Methyl-accepting chemotaxis protein	408
2918250135	158	99.36	1	156	1	155	1.5e-47	156.1	COG2954	CYTH domain, found in class IV adenylate cyclase and various triphosphatases	156
2918250137	51	8.81	2	26	20	33	2.7e-01	3.4	COG1580	Flagellar basal body-associated protein FliL	159
2918250137	51	11.32	27	51	15	32	2.7e-01	6	COG1580	Flagellar basal body-associated protein FliL	159
2918250139	367	84.97	2	356	3	330	8.7e-31	101.1	COG2327	Polysaccharide pyruvyl transferase family protein WcaK	385
2918250140	650	99.82	79	631	1	551	0.0e+00	528.4	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918250142	197	41.39	6	159	61	161	7.0e-09	29.6	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2918250143	342	88.74	51	341	31	298	2.2e-52	171	COG2813	16S rRNA G1207 methylase RsmC	300
2918250144	157	96.08	4	157	5	151	8.0e-60	195.6	COG0691	tmRNA-binding protein	153
2918250145	291	97.66	1	291	4	295	2.1e-115	379.3	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918250146	625	97.36	323	618	2	296	2.0e-59	196.7	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2918250148	442	60	35	90	1	48	1.8e-03	12.3	COG5645	Uncharacterized conserved protein YceK	80
2918250149	161	98.83	1	161	3	171	5.7e-23	76.9	COG0629	Single-stranded DNA-binding protein	167
2918250150	142	92.48	19	142	6	128	1.9e-17	58	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918250153	184	55.08	1	98	33	97	6.0e-04	13.9	COG2919	Cell division protein FtsB	117
2918250154	192	45.32	1	118	7	69	2.3e-04	14.1	COG4768	Uncharacterized protein YoxC, contains an MCP-like domain	139
2918250155	368	90.78	5	333	14	328	2.7e-74	244.6	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2918250157	259	96.41	19	259	4	245	1.6e-66	219	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918250158	255	94.57	1	248	12	255	2.0e-72	238.5	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918250159	317	91.94	1	312	4	311	4.5e-59	195	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918250160	275	67.92	148	275	49	156	4.1e-18	61.3	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918250160	275	81.13	1	146	5	133	4.1e-18	4.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918250161	342	93.66	3	342	10	334	2.9e-65	215.2	COG3239	Fatty acid desaturase	343
2918250162	416	15.35	290	400	256	348	1.3e-56	37.6	COG0443	Molecular chaperone DnaK (HSP70)	579
2918250162	416	50.99	1	301	7	315	1.3e-56	149.1	COG0443	Molecular chaperone DnaK (HSP70)	579
2918250163	335	92.54	3	244	3	250	2.8e-62	205.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918250164	77	73.75	1	76	12	70	3.0e-15	50.7	COG0425	TusA-related sulfurtransferase	78
2918250165	425	90	187	421	18	242	9.5e-18	56.9	COG2014	Uncharacterized conserved protein, contains DUF4213 and DUF364 domains	250
2918250166	110	96.15	1	102	3	102	8.0e-50	162.2	COG3492	Uncharacterized protein	104
2918250167	208	94.88	1	206	2	205	4.7e-39	129.1	COG0625	Glutathione S-transferase	211
2918250168	312	53.02	5	194	3	125	2.7e-20	67.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918250169	434	80.71	4	427	81	423	1.1e-53	173.1	COG0840	Methyl-accepting chemotaxis protein	408
2918250171	504	97.81	320	500	5	183	3.7e-56	184	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918250172	362	96.4	23	357	6	353	8.3e-71	233.2	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2918250173	320	96.25	2	320	7	314	1.8e-101	334	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
2918250174	498	99.38	15	498	2	484	0.0e+00	639.3	COG1492	Cobyric acid synthase	486
2918250175	214	98.99	17	214	3	198	4.7e-81	265.9	COG2109	ATP:corrinoid adenosyltransferase	198
2918250176	176	98.86	6	173	2	174	2.8e-62	204.2	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
2918250177	158	86.96	11	158	13	152	1.0e-50	165.9	COG3837	Uncharacterized conserved protein, cupin superfamily	161
2918250178	268	94.58	6	262	15	293	2.7e-26	87.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918250180	301	97.34	4	296	2	294	3.7e-62	205.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918250181	485	96.01	1	484	15	495	0.0e+00	730.2	COG0753	Catalase	496
2918250182	162	70.37	4	142	41	154	1.8e-08	29.6	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918250183	257	92.75	3	256	7	262	2.4e-83	274	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
2918250184	309	98.13	1	269	2	264	2.2e-86	284	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
2918250185	327	96.12	1	319	5	326	4.7e-89	293	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2918250186	153	94.23	7	153	2	148	4.9e-61	200	COG0328	Ribonuclease HI	154
2918250187	191	96.39	3	191	8	194	1.8e-68	224.4	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
2918250188	709	73.49	155	688	162	610	1.3e-98	326	COG4232	Thiol:disulfide interchange protein	569
2918250189	160	100	1	160	1	166	1.1e-63	208.3	COG0678	Peroxiredoxin	165
2918250190	150	95.97	1	147	5	147	2.5e-50	164.9	COG0314	Molybdopterin synthase catalytic subunit	149
2918250191	83	97.62	1	83	3	84	2.2e-25	84	COG1977	Molybdopterin converting factor, small subunit	84
2918250192	421	98.53	10	421	5	405	0.0e+00	448.5	COG0303	Molybdopterin biosynthesis enzyme	404
2918250193	208	97.75	1	208	2	218	1.3e-33	111.5	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918250194	167	98.77	1	161	2	161	1.2e-44	146.9	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
2918250195	201	92.27	1	186	11	189	2.6e-46	152.8	COG0558	Phosphatidylglycerophosphate synthase	192
2918250196	656	99.5	46	652	4	598	0.0e+00	736.6	COG0322	Excinuclease UvrABC, nuclease subunit	581
2918250197	256	98.13	3	243	4	266	1.5e-53	176.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918250201	235	87.69	2	232	2	236	1.9e-54	179.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918250202	482	97.02	12	476	2	457	0.0e+00	631.2	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
2918250203	228	84.07	6	186	4	156	1.4e-27	91.4	COG1286	Uncharacterized membrane protein, required for colicin V production	182
2918250204	468	98.46	1	455	2	450	0.0e+00	618.1	COG1066	Predicted ATP-dependent serine protease	456
2918250205	269	98.06	7	260	5	308	1.1e-83	275.6	COG0024	Methionine aminopeptidase	255
2918250206	202	62.79	39	188	17	124	1.2e-14	49.1	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918250207	198	92	1	183	5	188	9.0e-23	75.2	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
2918250208	145	90.24	1	145	5	152	5.3e-49	161.1	COG3542	Predicted sugar epimerase, cupin superfamily	162
2918250209	468	99.1	1	467	4	444	0.0e+00	558.5	COG1160	Predicted GTPases	444
2918250210	448	28.28	331	448	70	181	1.3e-42	31.1	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
2918250210	448	66.41	76	352	48	310	1.3e-42	112.9	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
2918250211	214	93.21	1	212	3	208	2.5e-42	139.5	COG4649	Uncharacterized protein	221
2918250212	214	98.1	1	214	1	207	4.3e-56	184.5	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918250213	247	97.63	23	223	2	207	9.6e-18	58.9	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918250214	232	98.1	4	214	3	209	7.4e-53	173.8	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918250215	59	12.71	4	56	116	160	3.4e-03	10.8	COG0306	Phosphate/sulfate permease	326
2918250216	456	57.7	73	366	12	232	1.1e-07	22	COG1474	Cdc6-related protein, AAA superfamily ATPase	366
2918250218	160	96.99	17	149	4	132	1.2e-17	58.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918250220	259	98.13	4	256	4	266	1.0e-48	160.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918250221	233	57.04	1	233	93	339	8.5e-37	118.7	COG0593	Chromosomal replication initiation ATPase DnaA	408
2918250222	355	93.33	1	350	13	348	5.3e-83	273.6	COG0628	Predicted PurR-regulated permease PerM	355
2918250223	186	88.66	1	183	14	185	8.7e-32	105.4	COG0558	Phosphatidylglycerophosphate synthase	192
2918250225	353	97.1	1	345	4	338	0.0e+00	470.6	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
2918250226	219	98	6	206	2	197	1.9e-75	247.5	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
2918250229	302	95.21	3	302	14	311	2.9e-59	195.5	COG2017	Galactose mutarotase or related enzyme	308
2918250232	1118	86.39	3	313	16	307	1.6e-54	179.7	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2918250232	1118	99.38	284	1118	2	804	0.0e+00	1138.8	COG4196	Uncharacterized conserved protein, DUF2126 family	808
2918250233	684	9.76	118	165	70	85	1.0e-08	4.7	COG2010	Cytochrome c, mono- and diheme variants	150
2918250233	684	22.56	291	368	44	80	1.0e-08	18	COG2010	Cytochrome c, mono- and diheme variants	150
2918250234	849	97.13	19	504	9	482	0.0e+00	594.8	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
2918250234	849	99.04	524	846	1	310	5.3e-67	220.9	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2918250235	317	87.87	15	316	9	305	2.1e-54	180	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2918250236	126	25.27	1	126	5	122	1.7e-23	77.9	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918250237	531	50.83	85	520	295	601	5.6e-53	174.5	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2918250238	535	99.24	1	527	4	527	0.0e+00	770	COG4108	Peptide chain release factor RF-3	528
2918250239	85	35.67	1	79	2	62	1.2e-16	55.8	COG4675	Microcystin-dependent protein  (function unknown)	170
2918250240	344	98.81	10	344	3	334	1.1e-111	368.3	COG0136	Aspartate-semialdehyde dehydrogenase	334
2918250241	833	99.2	9	821	6	751	0.0e+00	961.1	COG0058	Glucan phosphorylase	750
2918250242	141	86.24	1	141	21	183	3.6e-30	100.1	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918250243	157	87.63	1	157	16	178	8.2e-38	124.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918250244	286	98.88	38	284	2	266	4.8e-72	237.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918250245	74	26.46	2	74	6	73	7.6e-12	40.4	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2918250247	444	14.29	4	76	25	65	3.9e-70	3.8	COG4976	Predicted methyltransferase, contains TPR repeat	287
2918250247	444	98.95	149	444	2	285	3.9e-70	231.3	COG4976	Predicted methyltransferase, contains TPR repeat	287
2918250249	279	100	1	278	1	279	6.9e-109	357.8	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
2918250250	220	25.95	2	66	110	150	1.4e-07	3.8	COG5490	Uncharacterized protein	158
2918250250	220	77.85	69	217	30	152	1.4e-07	26.6	COG5490	Uncharacterized protein	158
2918250251	410	98.09	10	387	5	363	4.9e-47	155.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918250252	423	93.58	1	417	4	411	8.6e-60	197	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
2918250253	157	94.74	10	144	3	128	3.0e-19	64	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918250254	353	99.62	1	324	2	265	9.0e-75	245.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918250255	297	97.35	1	297	3	296	4.3e-53	174.9	COG1597	Diacylglycerol kinase family enzyme	301
2918250256	282	84.3	2	264	1	333	3.0e-25	82.5	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2918250257	334	98.48	6	334	5	329	0.0e+00	471.1	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
2918250258	328	97.66	51	317	2	251	1.3e-68	225.4	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918250259	91	95.74	1	91	2	91	2.0e-34	112.4	COG0776	Bacterial nucleoid DNA-binding protein	94
2918250260	135	89.19	1	135	9	140	1.7e-61	201.2	COG4957	Predicted transcriptional regulator	148
2918250261	296	78.01	3	289	67	332	1.8e-86	285.2	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918250262	448	77.18	22	443	96	423	1.3e-60	200.3	COG0840	Methyl-accepting chemotaxis protein	408
2918250264	194	83.07	21	174	14	170	2.9e-13	43.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918250266	493	98.96	1	491	1	476	0.0e+00	587.4	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918250267	95	98.96	1	95	1	95	2.5e-29	96.3	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
2918250269	188	95.74	15	159	2	136	6.8e-40	130.8	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
2918250270	277	77.75	1	267	7	324	1.7e-25	80.9	COG0672	High-affinity Fe2+/Pb2+ permease	383
2918250271	116	67.97	9	116	36	122	1.0e-04	17.4	COG3794	Plastocyanin	128
2918250272	137	94.07	2	135	6	132	3.2e-29	96.2	COG3791	Uncharacterized conserved protein	133
2918250273	142	88.15	7	138	6	124	1.1e-28	94.3	COG3791	Uncharacterized conserved protein	133
2918250274	78	77.78	11	77	15	63	6.0e-20	65.5	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918250275	296	98.34	6	296	2	297	2.4e-73	242.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918250276	320	98.1	7	317	5	313	4.3e-116	381.9	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
2918250277	430	96.98	5	430	7	424	0.0e+00	460.9	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2918250278	205	99.02	1	197	2	204	4.7e-62	204.1	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
2918250279	131	85.51	1	131	21	138	4.9e-50	163.7	COG4315	Predicted lipoprotein with conserved Yx(FWY)xxD motif (function unknown)	138
2918250283	58	36.67	1	53	7	50	2.5e-03	13.1	COG5499	Antitoxin component HigA of the HigAB toxin-antitoxin module, contains an N-terminal HTH domain	120
2918250284	357	86.58	9	351	44	359	5.7e-33	108.5	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918250285	207	84.88	39	194	14	159	6.7e-20	66.2	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918250286	333	98.34	3	314	5	301	7.8e-109	357.9	COG0031	Cysteine synthase	300
2918250287	235	96.71	1	235	4	238	4.2e-78	256.9	COG2872	Ser-tRNA(Ala) deacylase AlaX (editing enzyme)	241
2918250288	300	96.17	11	298	11	286	3.1e-87	286.9	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2918250289	145	38.62	3	130	89	161	1.8e-16	55.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918250290	205	72.84	46	185	42	159	1.8e-08	29.1	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918250291	361	98.34	5	361	3	357	7.1e-97	319.1	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2918250292	258	99.17	16	256	2	241	1.1e-117	386.1	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918250293	369	92.54	106	367	18	228	1.6e-66	218.5	COG0765	ABC-type amino acid transport system, permease component	222
2918250294	399	96.22	5	399	16	397	0.0e+00	536.2	COG4597	ABC-type amino acid transport system, permease component	397
2918250295	339	90.46	1	260	7	262	7.3e-43	141.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918250296	392	98.49	1	389	6	396	3.6e-123	405.9	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2918250297	143	93.75	4	113	6	110	1.7e-42	138.4	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
2918250300	137	68.42	7	130	19	122	3.6e-12	40.7	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
2918250301	350	95.76	1	344	5	343	1.9e-64	212.2	COG3500	Phage protein D	350
2918250302	69	94.29	1	69	4	69	1.3e-22	74.2	COG5004	P2-like prophage tail protein X	70
2918250303	151	85.03	5	139	2	126	5.0e-37	121.4	COG3499	Phage protein U	147
2918250307	171	99.41	1	171	2	169	6.4e-58	189.9	COG3498	Phage tail tube protein FII	169
2918250308	471	15.17	86	185	154	224	1.4e-124	31	COG3497	Phage tail sheath protein FI	394
2918250308	471	21.58	1	97	1	101	1.4e-124	88.6	COG3497	Phage tail sheath protein FI	394
2918250308	471	60.68	164	471	179	462	1.4e-124	299.3	COG3497	Phage tail sheath protein FI	394
2918250313	280	96.73	1	279	6	301	6.4e-59	189.1	COG3948	Phage-related baseplate assembly protein	306
2918250314	112	94.83	1	112	6	115	2.5e-36	118.6	COG3628	Phage baseplate assembly protein W	116
2918250317	153	76.09	10	153	2	141	9.6e-37	120.9	COG4540	Phage P2 baseplate assembly protein gpV	184
2918250320	628	88.72	132	627	6	123	1.0e-27	90.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918250321	858	65.38	730	858	4	122	3.8e-12	40.2	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918250321	858	82.99	309	725	64	390	5.5e-54	179.1	COG0642	Signal transduction histidine kinase	336
2918250323	140	98.52	2	136	2	134	4.1e-59	192.9	COG0105	Nucleoside diphosphate kinase	135
2918250324	631	98.5	1	519	3	529	0.0e+00	584.3	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918250325	224	94.74	20	223	7	204	1.4e-33	110.6	COG3932	Uncharacterized conserved protein	209
2918250326	145	96.58	2	115	3	115	1.8e-11	38.8	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2918250327	342	96.42	1	338	5	327	4.7e-68	224.5	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918250328	267	94.96	2	262	12	256	3.8e-72	237.4	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918250329	283	94.02	18	276	12	247	3.2e-89	293.2	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918250330	595	95.84	8	590	20	595	0.0e+00	638	COG0465	ATP-dependent Zn proteases	596
2918250331	204	55.38	22	151	3	74	1.4e-12	43.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918250332	261	70.67	5	261	70	269	3.5e-13	44.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918250333	531	68.75	218	514	111	363	4.2e-28	92.1	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2918250334	251	98.71	4	244	2	230	8.0e-56	183.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918250335	353	71.07	5	342	110	389	1.0e-42	141.8	COG0642	Signal transduction histidine kinase	336
2918250338	585	73.35	46	585	99	387	7.2e-57	187	COG0642	Signal transduction histidine kinase	336
2918250341	106	77.08	1	81	17	90	2.2e-23	77	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
2918250344	237	98.17	11	224	3	216	9.0e-31	101.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918250346	251	91.89	25	244	4	207	6.4e-70	229.5	COG2928	Uncharacterized membrane protein	222
2918250347	693	96.9	3	682	9	665	0.0e+00	816.3	COG1200	RecG-like helicase	677
2918250348	988	98.54	1	982	5	747	0.0e+00	477.1	COG0643	Chemotaxis protein histidine kinase CheA	716
2918250349	140	36.36	3	138	2	129	6.3e-31	102.3	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918250350	361	96.59	6	359	2	341	8.6e-86	282.7	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918250351	465	24.85	159	262	31	71	1.5e-29	4	COG0835	Chemotaxis signal transduction protein	165
2918250351	465	80	1	138	20	151	1.5e-29	55.4	COG0835	Chemotaxis signal transduction protein	165
2918250351	465	81.82	315	462	19	153	1.5e-29	34.1	COG0835	Chemotaxis signal transduction protein	165
2918250352	306	95.93	22	302	6	264	4.5e-55	180.8	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918250353	689	83.29	252	688	71	424	3.8e-66	218.5	COG0840	Methyl-accepting chemotaxis protein	408
2918250356	337	95.93	2	326	12	341	9.7e-96	314.9	COG1559	Cell division protein YceG, involved in septum cleavage	342
2918250357	420	99.28	1	420	2	412	0.0e+00	545.7	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918250358	79	95.06	1	78	3	79	3.5e-28	92.4	COG0236	Acyl carrier protein	80
2918250359	245	99.25	2	244	2	267	2.6e-78	257.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918250360	316	95.29	1	314	4	327	3.5e-80	264.1	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
2918250361	329	83.55	10	313	21	345	1.0e-12	41	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918250362	146	97.32	2	113	3	111	5.5e-37	120.7	COG0360	Ribosomal protein S6	112
2918250363	90	89.87	7	85	9	79	1.7e-31	103.3	COG0238	Ribosomal protein S18	75
2918250365	186	99.32	1	148	1	147	8.6e-50	163.2	COG0359	Ribosomal protein L9	148
2918250366	426	97.9	98	382	7	286	7.0e-110	361.1	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2918250367	407	96.57	1	400	15	408	0.0e+00	446	COG0538	Isocitrate dehydrogenase	407
2918250368	126	24.52	1	98	6	81	8.3e-07	23.3	COG4569	Acetaldehyde dehydrogenase (acetylating)	310
2918250369	947	98.27	48	927	9	860	0.0e+00	962	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
2918250373	904	99.18	20	900	6	852	0.0e+00	941	COG0249	DNA mismatch repair ATPase MutS	843
2918250374	274	84.94	5	268	11	230	3.7e-52	171.8	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2918250377	437	95.87	12	433	16	410	0.0e+00	466.6	COG2262	50S ribosomal subunit-associated GTPase HflX	411
2918250378	82	94.81	2	78	2	74	3.2e-36	117.5	COG1923	sRNA-binding regulator protein Hfq	77
2918250379	237	85.59	17	220	5	194	1.6e-31	104.5	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918250382	239	72	53	239	54	233	1.1e-14	49.2	COG2365	Protein tyrosine/serine phosphatase	249
2918250383	218	63.01	17	217	21	204	6.2e-33	108.7	COG1284	Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains	289
2918250385	321	27.17	224	321	233	326	5.4e-94	64.3	COG1171	Threonine dehydratase	347
2918250385	321	58.38	24	227	9	210	5.4e-94	246.3	COG1171	Threonine dehydratase	347
2918250386	281	82.73	1	279	19	291	2.9e-62	205.3	COG0714	MoxR-like ATPase	329
2918250387	889	98.87	1	887	7	878	0.0e+00	1133.8	COG0013	Alanyl-tRNA synthetase	879
2918250388	140	71.11	1	127	4	99	7.0e-22	72.5	COG3791	Uncharacterized conserved protein	133
2918250389	263	95.75	7	263	4	251	5.5e-87	286.2	COG0805	Sec-independent protein secretion pathway component TatC	255
2918250390	169	84.04	1	92	1	79	9.1e-17	55.8	COG1826	Sec-independent protein translocase protein TatA	94
2918250391	79	79.79	1	78	1	75	2.1e-20	67.7	COG1826	Sec-independent protein translocase protein TatA	94
2918250392	207	92.39	12	185	11	180	3.6e-56	184.2	COG1386	Chromosome segregation and condensation protein ScpB	184
2918250393	277	96.77	28	274	2	241	1.1e-59	196.8	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
2918250394	225	86.44	1	224	19	222	3.5e-33	109.8	COG1994	Zn-dependent protease (includes SpoIVFB)	230
2918250395	356	74.58	16	350	7	317	5.5e-72	237.7	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2918250397	586	99.83	1	584	1	580	0.0e+00	515.8	COG0018	Arginyl-tRNA synthetase	577
2918250398	399	98.81	1	396	4	419	6.2e-115	379.6	COG0232	dGTP triphosphohydrolase	412
2918250399	124	96.36	16	124	4	109	2.7e-42	137.8	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2918250400	257	99.23	1	256	2	258	2.4e-81	267.5	COG0708	Exonuclease III	261
2918250403	381	77.88	3	97	6	86	5.2e-18	58.3	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
2918250406	115	98.13	1	108	2	106	2.4e-24	80.1	COG5471	Predicted phage recombinase, RecA/RadA family	107
2918250409	485	93.66	4	485	26	498	2.8e-91	301.1	COG5511	Bacteriophage capsid protein	492
2918250410	351	45.51	7	346	309	602	1.0e-51	170.7	COG5525	Phage terminase, large subunit GpA	611
2918250412	43	31.58	1	41	25	66	1.5e-08	29.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918250413	556	81.41	58	551	78	423	2.1e-58	191.9	COG0840	Methyl-accepting chemotaxis protein	408
2918250414	722	87.76	242	709	50	422	1.4e-47	156.3	COG0840	Methyl-accepting chemotaxis protein	408
2918250415	1121	59.24	874	1025	2	126	2.9e-24	78.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918250415	1121	67.01	524	854	127	390	2.3e-75	249.4	COG0642	Signal transduction histidine kinase	336
2918250416	348	93.78	1	343	15	361	1.7e-96	318	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2918250417	793	34.4	691	788	47	89	3.8e-04	14.7	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918250417	793	68.02	221	535	125	392	1.6e-69	230.2	COG0642	Signal transduction histidine kinase	336
2918250417	793	93.98	548	680	5	129	3.5e-36	116.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918250418	123	94.52	2	122	5	142	2.8e-09	32.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918250420	229	74.12	1	229	4	235	1.0e-77	256.5	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2918250421	442	56.25	91	338	134	331	2.6e-66	218.9	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2918250422	235	83.03	18	216	26	206	1.1e-24	81.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918250423	488	97.98	29	469	2	390	3.8e-109	359.7	COG0348	Polyferredoxin	386
2918250426	371	12.4	16	241	10	39	2.8e-04	14.7	COG1100	GTPase SAR1 family domain	219
2918250434	177	10.7	40	174	267	391	2.3e-05	16.6	COG1196	Chromosome segregation ATPase	1163
2918250435	214	34.64	8	133	65	126	2.6e-04	15.4	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
2918250438	245	92.04	1	225	5	212	5.8e-57	187.2	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918250441	259	72.87	144	247	33	126	4.1e-04	13	COG2149	Uncharacterized membrane protein YidH, DUF202 family	120
2918250443	211	78.26	11	195	6	167	4.6e-14	46.8	COG4245	Uncharacterized conserved protein YegL, contains vWA domain of TerY type	207
2918250445	1676	83.87	292	1013	2	734	2.8e-106	351	COG3899	Predicted ATPase	849
2918250445	1676	90.79	1308	1673	18	224	1.9e-65	214.4	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918250446	518	66.5	176	515	129	390	1.9e-49	164.2	COG0642	Signal transduction histidine kinase	336
2918250446	518	93.98	1	130	5	129	2.6e-27	88.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918250447	216	96.53	7	207	6	200	5.2e-72	236.1	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918250448	322	77.27	172	311	25	126	4.9e-31	101.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918250449	278	98.31	4	278	4	293	2.1e-50	166.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918250450	228	92.23	9	202	4	193	5.6e-17	54.9	COG1335	Nicotinamidase-related amidase	205
2918250451	94	84.95	1	86	1	79	6.4e-32	104.2	COG4317	Xanthosine utilization system component, XapX domain	93
2918250452	618	98.88	2	537	5	533	0.0e+00	556.3	COG1574	Predicted amidohydrolase YtcJ	535
2918250453	153	77.08	26	147	16	126	1.3e-16	55.7	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918250454	541	49.62	3	210	194	389	6.1e-19	26.3	COG2814	Predicted arabinose efflux permease, MFS family	394
2918250454	541	85.82	50	413	45	383	6.1e-19	50.6	COG2814	Predicted arabinose efflux permease, MFS family	394
2918250455	546	95.79	1	540	5	527	5.8e-124	409.1	COG4615	ABC-type siderophore export system, fused ATPase and permease components	546
2918250456	2500	43.01	1530	1752	42	161	1.9e-05	18.1	COG0500	SAM-dependent methyltransferase	257
2918250456	2500	56.76	561	610	28	69	2.1e-06	4.9	COG3433	Aryl carrier domain	74
2918250456	2500	63.43	5	443	238	648	0.0e+00	278.7	COG1020	Non-ribosomal peptide synthetase component F	642
2918250456	2500	68.92	1938	2009	16	66	2.1e-06	14.4	COG3433	Aryl carrier domain	74
2918250456	2500	99.38	858	1504	4	647	0.0e+00	437.1	COG1020	Non-ribosomal peptide synthetase component F	642
2918250457	643	96.35	1	610	1	528	0.0e+00	447.4	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2918250458	4902	15.43	366	490	547	646	0.0e+00	43.7	COG1020	Non-ribosomal peptide synthetase component F	642
2918250458	4902	27.01	3	226	253	427	0.0e+00	24.5	COG1020	Non-ribosomal peptide synthetase component F	642
2918250458	4902	33.02	4667	4894	2	215	0.0e+00	83.7	COG1020	Non-ribosomal peptide synthetase component F	642
2918250458	4902	34.72	2488	2712	7	231	0.0e+00	41.4	COG1020	Non-ribosomal peptide synthetase component F	642
2918250458	4902	58.64	3154	3611	3	382	0.0e+00	84.4	COG1020	Non-ribosomal peptide synthetase component F	642
2918250458	4902	81.04	700	2023	7	968	0.0e+00	1011.2	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2918250458	4902	99.38	3596	4248	4	647	0.0e+00	489.6	COG1020	Non-ribosomal peptide synthetase component F	642
2918250459	1094	78.34	520	1094	129	591	5.0e-11	31.1	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
2918250459	1094	84.65	20	427	36	377	9.9e-46	150	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918250460	195	78.42	23	162	2	110	2.8e-18	60.6	COG3597	Uncharacterized conserved protein, DUF697 family	139
2918250461	75	15.17	1	65	241	299	5.0e-04	13.7	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918250462	492	96.68	30	349	7	297	6.9e-17	55.6	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918250463	445	65.81	22	445	159	466	3.0e-23	77.1	COG5338	Uncharacterized protein	468
2918250464	1341	95.72	1112	1341	7	252	4.1e-22	68.3	COG3319	Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase	257
2918250464	1341	99.69	244	908	3	648	1.0e-105	349.7	COG1020	Non-ribosomal peptide synthetase component F	642
2918250465	322	11.85	201	314	238	271	7.5e-11	10.6	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2918250465	322	45.3	1	165	15	144	7.5e-11	23.8	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2918250467	440	70.98	96	432	12	307	1.7e-55	183.3	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2918250468	452	95.03	22	451	9	429	1.7e-74	244.6	COG4452	Inner membrane protein involved in colicin E2 resistance	443
2918250469	230	98.28	5	229	2	229	1.2e-81	268	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918250470	535	84.26	120	534	56	387	1.1e-51	170.7	COG0642	Signal transduction histidine kinase	336
2918250471	953	89	359	953	66	591	4.1e-52	171.9	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
2918250472	471	99.15	9	471	2	466	1.9e-117	387.5	COG0277	FAD/FMN-containing dehydrogenase	459
2918250473	240	99.16	4	240	2	236	3.8e-92	302.4	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918250474	262	99.61	5	257	2	254	8.0e-98	321.4	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918250475	335	95.05	24	327	14	320	7.3e-79	259.9	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918250476	292	98.01	2	290	2	296	3.3e-77	254.6	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918250477	376	95.63	10	373	3	352	1.4e-53	176.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918250478	287	97.59	1	285	7	290	4.7e-69	227.4	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
2918250479	182	94.82	1	179	5	187	2.0e-22	74.5	COG0066	3-isopropylmalate dehydratase small subunit	191
2918250480	418	99.07	1	418	3	427	2.5e-92	304.5	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
2918250481	532	98.93	19	530	1	464	2.6e-51	167.7	COG0277	FAD/FMN-containing dehydrogenase	459
2918250482	307	76.15	13	304	27	224	4.0e-32	106.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918250483	294	98.78	31	276	2	244	3.6e-62	204.1	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918250486	462	48.3	271	461	5	189	1.1e-41	43.8	COG0477	MFS family permease	338
2918250486	462	69.97	23	285	3	270	1.1e-41	99.2	COG0477	MFS family permease	338
2918250488	200	49.82	2	197	54	192	5.2e-09	31.5	COG0500	SAM-dependent methyltransferase	257
2918250489	399	95.7	6	386	15	370	0.0e+00	486.8	COG2021	Homoserine acetyltransferase	368
2918250490	302	86.14	1	95	7	93	7.5e-17	55.7	COG1605	Chorismate mutase	101
2918250491	363	98.61	8	363	3	358	5.1e-106	349.2	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2918250494	265	90.6	18	265	3	243	1.7e-49	163.4	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
2918250495	369	10.14	1	62	1	42	2.6e-47	25.4	COG1419	Flagellar biosynthesis GTPase FlhF	407
2918250495	369	46.38	111	326	211	402	2.6e-47	128.7	COG1419	Flagellar biosynthesis GTPase FlhF	407
2918250496	723	97.85	19	723	13	694	0.0e+00	852.4	COG1298	Flagellar biosynthesis pathway, component FlhA	696
2918250497	511	97.43	1	498	7	461	0.0e+00	463	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918250498	301	94.38	39	298	1	252	5.2e-55	180.8	COG1291	Flagellar motor component MotA	266
2918250499	104	62.41	2	98	54	141	3.3e-31	103.5	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
2918250500	257	76.13	9	248	32	216	3.2e-20	66.3	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
2918250501	553	98.18	1	552	10	547	0.0e+00	503.9	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
2918250502	172	57.69	18	143	2	76	3.8e-17	57.3	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918250503	212	41.24	42	189	44	123	2.6e-05	18.9	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
2918250504	710	60.8	595	698	11	86	1.3e-08	29.1	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918250504	710	60.99	446	583	12	122	5.3e-04	13.4	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918250504	710	74.87	40	429	97	391	3.8e-81	268.4	COG0642	Signal transduction histidine kinase	336
2918250505	144	87.97	16	144	8	124	1.9e-25	83.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918250506	211	96.65	6	210	3	204	4.1e-48	158	COG3932	Uncharacterized conserved protein	209
2918250507	433	97.95	1	432	3	431	0.0e+00	469.4	COG1253	Hemolysin or related protein, contains CBS domains	429
2918250508	150	86.16	1	147	13	149	3.1e-35	115.4	COG2030	Acyl dehydratase	159
2918250510	543	63.73	2	270	14	201	1.0e-21	5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918250510	543	89.49	263	539	7	270	1.0e-21	72.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918250511	538	96.83	25	537	10	559	7.0e-102	336	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918250512	281	98.71	31	272	2	230	1.2e-33	110.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918250513	165	55.92	36	164	5	122	8.9e-09	29.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918250515	254	96.68	29	245	3	206	1.6e-48	159.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918250516	387	83.99	3	374	34	374	1.8e-14	47.7	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
2918250517	615	67.51	3	295	40	280	2.8e-29	97.2	COG2273	Beta-glucanase, GH16 family	355
2918250518	425	81.59	31	418	57	406	3.6e-14	45.7	COG3307	O-antigen ligase	424
2918250519	448	81.12	11	440	14	404	6.1e-17	55.2	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2918250520	782	71.68	537	777	44	248	5.5e-37	120.4	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918250520	782	95.48	36	517	22	465	6.1e-79	259.8	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918250521	406	81.42	21	392	71	403	5.9e-35	116.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918250522	233	84.89	6	233	35	225	3.7e-70	230.3	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2918250523	426	87.19	13	425	29	382	7.6e-54	177.5	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
2918250524	281	63.31	6	279	42	267	1.3e-38	127.7	COG2273	Beta-glucanase, GH16 family	355
2918250525	144	97.74	8	138	2	131	1.4e-11	39.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918250527	370	46.45	18	363	209	398	2.2e-26	88.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918250528	263	97.16	41	261	1	205	1.2e-46	153.5	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918250529	1617	94.06	44	1615	95	1630	0.0e+00	959.9	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
2918250531	151	78.03	19	146	2	104	7.4e-28	92.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918250532	378	99.75	1	378	1	393	4.0e-127	419.2	COG0183	Acetyl-CoA acetyltransferase	392
2918250533	778	20.06	314	464	181	246	2.1e-84	20.7	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918250533	778	79.62	459	738	15	225	4.0e-34	112.5	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918250533	778	87.54	1	334	1	288	2.1e-84	256.1	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918250534	596	97.24	25	460	7	394	4.2e-106	350.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918250535	213	96.68	1	212	1	204	1.6e-59	195.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918250536	144	42.94	67	141	3	72	6.4e-32	41.8	COG0517	CBS domain	117
2918250536	144	94.48	2	122	10	163	6.4e-32	76.2	COG0517	CBS domain	117
2918250537	233	97.71	5	233	6	218	1.6e-61	202.4	COG3047	Outer membrane protein W	213
2918250539	379	98.71	2	379	4	386	2.2e-64	212.7	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918250541	352	96.61	2	350	9	350	1.8e-118	390.7	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
2918250542	158	85.08	1	154	25	178	3.4e-30	100.1	COG5389	Uncharacterized protein	181
2918250543	216	68.27	7	216	80	249	2.2e-37	123.6	COG1651	Protein-disulfide isomerase	244
2918250544	1153	99.83	1	1150	2	1167	0.0e+00	797.7	COG1196	Chromosome segregation ATPase	1163
2918250545	552	92.33	229	539	22	298	1.7e-55	182.8	COG2382	Enterochelin esterase or related enzyme	299
2918250546	2412	41.89	991	1041	16	46	5.5e-04	3.8	COG3433	Aryl carrier domain	74
2918250546	2412	72.97	2072	2142	8	61	5.5e-04	7.4	COG3433	Aryl carrier domain	74
2918250546	2412	98.83	2164	2402	1	254	1.9e-46	152.4	COG3319	Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase	257
2918250546	2412	99.54	1314	1973	4	648	0.0e+00	451.3	COG1020	Non-ribosomal peptide synthetase component F	642
2918250546	2412	99.69	236	898	3	648	0.0e+00	355.1	COG1020	Non-ribosomal peptide synthetase component F	642
2918250547	78	88.73	5	72	3	65	1.9e-26	86.2	COG3251	Uncharacterized conserved protein YbdZ, MbtH family	71
2918250548	253	98.51	2	250	3	266	4.8e-62	204.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918250549	287	79.73	212	287	14	72	2.8e-21	69	COG3433	Aryl carrier domain	74
2918250549	287	95.41	1	217	1	208	4.2e-90	295.4	COG1535	Isochorismate hydrolase	218
2918250550	562	98.52	1	552	7	540	0.0e+00	726.1	COG1021	Non-ribosomal peptide synthetase component E (peptide arylation enzyme)	542
2918250551	403	89.65	8	391	44	424	1.4e-113	374.9	COG1169	Isochorismate synthase EntC	423
2918250552	1064	99.8	1	1042	2	1013	0.0e+00	707.1	COG0841	Multidrug efflux pump subunit AcrB	1009
2918250553	374	95.64	1	373	13	385	2.0e-50	166.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918250554	428	51.44	217	425	14	210	4.0e-14	7.1	COG0477	MFS family permease	338
2918250554	428	56.4	12	240	5	220	4.0e-14	42.7	COG0477	MFS family permease	338
2918250555	667	98.29	24	667	13	700	0.0e+00	504.9	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
2918250556	537	19.64	308	449	339	425	4.0e-36	22.3	COG3182	Uncharacterized iron-regulated membrane protein	442
2918250556	537	47.18	1	227	1	209	4.0e-36	104.3	COG3182	Uncharacterized iron-regulated membrane protein	442
2918250559	309	91.91	7	307	25	308	9.7e-70	229.6	COG3386	Sugar lactone lactonase YvrE	307
2918250560	509	98.21	1	501	1	495	0.0e+00	549.9	COG3333	TctA family transporter	504
2918250562	321	98.75	6	321	4	318	6.8e-92	302.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918250563	216	96.21	6	215	5	207	3.4e-60	197.5	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
2918250564	340	91.5	6	328	5	284	1.1e-74	245.8	COG3734	2-keto-3-deoxy-galactonokinase	306
2918250565	277	100	22	267	1	246	4.5e-67	220.2	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918250566	258	99.25	3	256	2	267	2.6e-60	198.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918250567	218	84.86	7	180	27	183	1.8e-36	120.4	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
2918250568	325	93.71	10	324	19	316	9.7e-68	223.4	COG0657	Acetyl esterase/lipase	312
2918250569	370	95.99	9	359	5	339	2.5e-92	304	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
2918250570	334	89.88	6	334	20	312	8.0e-73	239.7	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918250571	415	88.78	16	406	7	378	9.3e-82	269.5	COG0498	Threonine synthase	411
2918250572	303	94.19	42	302	11	253	2.0e-60	198.9	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918250573	289	97.61	29	282	3	247	4.0e-83	273.3	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918250574	359	95.22	23	358	4	322	1.3e-39	130.9	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918250575	390	6.39	33	120	240	262	3.5e-11	1.4	COG3203	Outer membrane protein (porin)	354
2918250575	390	49.44	144	380	157	334	3.5e-11	37.6	COG3203	Outer membrane protein (porin)	354
2918250578	385	82.87	1	355	2	267	8.9e-19	62.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918250579	556	94.51	1	544	12	527	2.4e-101	334.4	COG4615	ABC-type siderophore export system, fused ATPase and permease components	546
2918250580	442	94.68	33	322	10	294	1.7e-17	57.4	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918250581	570	87.73	24	570	54	532	3.1e-85	281.3	COG4615	ABC-type siderophore export system, fused ATPase and permease components	546
2918250582	250	94.35	1	250	6	272	5.1e-31	102.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918250584	168	83.45	7	148	3	118	9.6e-18	58.9	COG3597	Uncharacterized conserved protein, DUF697 family	139
2918250585	1105	41.97	689	893	63	177	7.9e+00	10.3	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2918250586	242	37.88	48	227	144	243	6.0e-04	12.5	COG3455	Type VI protein secretion system component VasF	262
2918250589	1036	61.4	692	998	11	220	4.2e-28	92.5	COG0668	Small-conductance mechanosensitive channel	316
2918250589	1036	91.8	24	423	9	344	5.6e-35	115.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918250590	458	94.87	11	449	19	388	1.7e-35	117.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918250591	559	75.11	6	550	151	684	2.1e-104	344.6	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918250592	451	88.7	5	417	48	455	4.9e-46	152	COG1538	Outer membrane protein TolC	457
2918250594	187	94.57	2	185	2	175	7.6e-48	157.3	COG0431	NAD(P)H-dependent FMN reductase	184
2918250595	277	98.49	15	274	5	265	2.4e-47	156.1	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918250596	355	90.65	1	352	6	325	7.9e-114	375.1	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918250597	588	96.88	17	575	7	533	2.8e-119	393.6	COG1178	ABC-type Fe3+ transport system, permease component	540
2918250598	351	86.71	66	351	3	263	5.1e-35	115.9	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918250599	254	99.25	7	251	2	267	2.1e-71	235.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918250600	153	85.53	1	147	15	150	9.3e-38	123.6	COG2030	Acyl dehydratase	159
2918250601	138	75.89	9	124	18	124	5.2e-19	62.7	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
2918250602	389	98.22	5	389	4	390	4.6e-59	195.1	COG0183	Acetyl-CoA acetyltransferase	392
2918250603	400	98.75	1	400	5	400	0.0e+00	470.4	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918250604	303	97.67	6	299	3	296	1.4e-44	147.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918250605	501	93.31	6	498	27	556	2.8e-122	403.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918250606	169	92.09	12	148	9	136	6.9e-24	78.9	COG0824	Acyl-CoA thioesterase FadM	137
2918250607	247	23.82	82	209	247	337	2.2e-32	42.9	COG3448	CBS-domain-containing membrane protein	382
2918250607	247	33.77	1	151	248	376	2.2e-32	73.7	COG3448	CBS-domain-containing membrane protein	382
2918250608	439	45.69	257	438	15	189	1.6e-23	14.5	COG0477	MFS family permease	338
2918250608	439	62.14	27	306	8	245	1.6e-23	64.2	COG0477	MFS family permease	338
2918250609	377	98.03	4	268	3	251	9.1e-78	255.5	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2918250610	669	99.82	48	617	2	569	0.0e+00	782.5	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2918250611	214	91.55	3	213	18	212	1.3e-72	238.2	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918250612	139	92.86	5	132	8	111	9.5e-45	145.5	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
2918250613	265	94.88	10	265	7	247	1.3e-73	241.9	COG3346	Cytochrome oxidase assembly protein ShyY1	252
2918250614	435	93.4	20	430	23	390	1.2e-34	115.1	COG0642	Signal transduction histidine kinase	336
2918250615	194	96.15	14	194	7	181	4.0e-75	246.2	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918250617	1415	20.54	2	96	371	485	3.9e-08	27.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918250617	1415	20.75	1148	1278	261	349	8.6e-32	9.7	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2918250617	1415	24.24	429	564	288	391	8.6e-32	20.1	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2918250617	1415	27.51	1019	1177	256	373	8.6e-32	29.1	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2918250617	1415	29.6	869	1048	242	368	8.6e-32	32	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2918250617	1415	37.53	583	845	198	358	8.6e-32	43	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2918250617	1415	39.29	71	403	293	512	3.9e-08	11.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918250618	153	67.11	19	142	48	149	2.1e-22	74.4	COG0782	Transcription elongation factor, GreA/GreB family	151
2918250619	130	79.61	2	130	29	149	4.7e-17	57	COG0782	Transcription elongation factor, GreA/GreB family	151
2918250620	419	98.79	2	414	5	411	0.0e+00	500.9	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
2918250621	552	83.5	63	552	59	387	3.9e-45	149.4	COG0642	Signal transduction histidine kinase	336
2918250622	209	97.52	9	209	4	200	3.1e-70	230.4	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918250623	150	96.73	1	150	4	151	1.0e-55	182.9	COG3918	Uncharacterized membrane protein	153
2918250624	463	99.12	5	456	3	453	0.0e+00	446.3	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918250625	292	93.33	1	292	19	298	1.2e-85	281.7	COG4558	ABC-type hemin transport system, periplasmic component	300
2918250626	349	97.61	10	348	5	331	4.8e-94	309.7	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918250627	257	93.44	1	255	1	242	1.2e-78	258.4	COG4559	ABC-type hemin transport system, ATPase component	259
2918250628	160	98.09	1	158	1	154	2.5e-62	204.1	COG2193	Bacterioferritin (cytochrome b1)	157
2918250629	158	98.73	1	157	1	155	1.2e-61	201.9	COG2193	Bacterioferritin (cytochrome b1)	157
2918250630	138	93.38	1	134	6	132	1.7e-16	55.3	COG3631	Ketosteroid isomerase-related protein	133
2918250632	267	94.19	1	254	2	244	5.4e-78	256.4	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
2918250633	347	98.21	15	346	5	333	1.6e-76	252.1	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918250634	309	31.79	176	304	191	293	9.8e-23	11.6	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2918250634	309	44.14	24	171	52	194	9.8e-23	62.2	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2918250635	641	97.23	12	641	15	610	4.8e-119	393.3	COG4206	Outer membrane cobalamin receptor protein	608
2918250637	761	90.35	210	656	40	423	9.2e-61	201.2	COG0840	Methyl-accepting chemotaxis protein	408
2918250638	348	95.62	21	332	2	307	2.7e-118	389.5	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918250639	333	98.77	6	331	2	322	0.0e+00	452.5	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918250640	352	97.04	1	347	12	371	2.7e-110	363.2	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
2918250641	127	97.06	1	126	4	135	2.5e-32	106.4	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918250642	540	96.89	7	540	8	568	3.2e-101	334.2	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
2918250643	300	92.95	11	299	20	296	2.8e-102	336.3	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918250644	313	99.37	1	313	1	316	1.6e-111	367.4	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918250645	518	97.4	2	518	6	568	1.1e-81	270.1	COG0747	ABC-type transport system, periplasmic component	556
2918250646	252	97.97	11	252	2	242	1.2e-55	182.8	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918250647	281	97.63	5	275	6	293	8.8e-39	128.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918250648	148	63.83	27	133	29	118	2.8e-14	47.4	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
2918250649	381	97.97	1	375	1	386	7.5e-79	260.1	COG0183	Acetyl-CoA acetyltransferase	392
2918250650	275	99.19	27	273	2	245	1.6e-55	182.4	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918250651	418	97.51	1	405	5	395	2.0e-126	416.8	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918250652	259	99.25	7	250	2	267	5.1e-59	194.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918250653	251	99.25	1	249	1	266	2.1e-70	232	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918250654	183	96.58	21	173	2	142	4.7e-27	88.3	COG0757	3-dehydroquinate dehydratase	146
2918250655	337	96.39	4	333	8	327	6.1e-95	312.8	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918250656	628	85.31	23	193	14	164	2.8e-38	125.9	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918250656	628	98.42	253	628	1	373	2.0e-92	304.9	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918250657	288	74.62	12	282	19	212	3.3e-31	103.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918250658	108	92.45	1	104	2	99	2.0e-30	99.5	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
2918250659	673	53.02	4	133	3	125	1.9e-89	103.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918250659	673	53.45	132	265	3	126	1.9e-89	84.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918250659	673	53.45	269	453	2	125	1.9e-89	115.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918250660	360	96.59	3	352	2	341	4.8e-99	326.3	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918250661	768	13.26	2	116	10	109	2.6e-101	51.3	COG0643	Chemotaxis protein histidine kinase CheA	716
2918250661	768	51.86	107	620	356	746	2.6e-101	282	COG0643	Chemotaxis protein histidine kinase CheA	716
2918250661	768	94.74	612	741	4	129	7.7e-29	93.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918250662	490	65.65	151	486	143	421	2.6e-61	202.1	COG0840	Methyl-accepting chemotaxis protein	408
2918250663	193	89.7	28	193	14	161	4.7e-10	33.9	COG0835	Chemotaxis signal transduction protein	165
2918250664	547	98.15	27	300	4	268	6.4e-65	213.5	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918250665	147	66.06	1	130	46	154	2.1e-11	38.2	COG0835	Chemotaxis signal transduction protein	165
2918250666	312	62.69	10	308	142	388	7.1e-48	158.8	COG0642	Signal transduction histidine kinase	336
2918250667	127	93.98	1	127	5	129	4.4e-33	108.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918250668	1116	27.13	1	127	133	250	2.0e-47	39.8	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918250668	1116	28.05	953	1110	133	254	2.0e-47	44.2	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918250668	1116	37.24	533	707	264	425	2.0e-47	68.7	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918250668	1116	98.83	718	975	1	254	2.6e-97	318.8	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918250669	339	92.31	1	322	8	307	1.6e-94	311.3	COG0042	tRNA-dihydrouridine synthase	323
2918250670	392	92.62	21	387	5	343	2.9e-51	169.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918250671	345	95.68	2	344	3	290	3.3e-60	191.6	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918250672	601	95.05	11	327	13	319	4.0e-65	214.2	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918250672	601	98.82	349	599	3	253	2.2e-92	303.4	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918250673	242	98.73	3	237	3	236	2.0e-92	303.3	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918250674	256	97.36	2	253	6	263	7.0e-58	190.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918250675	627	84.33	33	606	13	491	5.1e-57	188.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918250676	253	98.13	1	249	3	265	2.0e-52	173.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918250677	204	92.48	47	175	5	127	5.8e-21	69.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918250678	597	97.49	19	462	7	395	5.5e-109	359.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918250679	289	84.87	2	289	44	301	2.2e-73	242	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2918250680	233	91.81	2	226	13	225	3.8e-39	128.9	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918250681	600	68.95	231	599	135	456	9.6e-121	398.2	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918250687	354	82.1	94	351	10	220	9.3e-54	176.6	COG0543	NAD(P)H-flavin reductase	252
2918250687	354	85.44	2	96	12	99	1.5e-18	60.7	COG0633	Ferredoxin	102
2918250688	132	64.08	25	116	33	98	5.0e-12	40	COG0633	Ferredoxin	102
2918250689	306	95.89	8	124	6	145	7.6e-09	12	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918250689	306	95.89	149	267	2	141	7.6e-09	22.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918250690	140	93.62	5	140	7	138	5.7e-36	118.4	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2918250691	508	98.75	26	508	3	475	0.0e+00	528.5	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918250692	262	99.24	1	262	2	263	3.9e-87	286.5	COG3971	2-keto-4-pentenoate hydratase	264
2918250693	310	95.81	1	309	3	299	0.0e+00	520.5	COG4569	Acetaldehyde dehydrogenase (acetylating)	310
2918250694	341	81.84	2	340	2	339	3.0e-59	195.7	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918250695	259	96.21	5	259	7	260	2.0e-79	261.1	COG3971	2-keto-4-pentenoate hydratase	264
2918250696	64	85.51	1	61	1	59	1.3e-13	45.2	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918250697	294	96.39	2	293	8	301	3.8e-86	283.7	COG4313	Uncharacterized conserved protein	304
2918250698	521	93.08	1	520	33	570	7.6e-122	402.8	COG0747	ABC-type transport system, periplasmic component	556
2918250699	1224	59.72	945	1099	3	128	1.8e-15	49.9	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918250699	1224	64	1097	1215	28	107	9.3e-09	28.1	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918250699	1224	84.52	374	762	56	388	2.3e-78	259.2	COG0642	Signal transduction histidine kinase	336
2918250700	147	93.23	5	138	6	129	1.4e-23	77.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918250702	284	36.15	13	142	14	60	2.3e-08	29.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918250703	295	93.46	1	293	2	301	3.6e-33	110	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918250704	586	81.88	54	584	78	425	5.6e-77	247	COG0840	Methyl-accepting chemotaxis protein	408
2918250705	577	94.14	17	567	13	542	0.0e+00	494.3	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2918250706	103	52.31	2	100	3	70	6.1e-07	25.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918250707	307	97.67	2	296	2	295	1.8e-74	245.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918250708	396	90.59	2	395	29	394	6.0e-67	221.2	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918250709	399	97.22	2	389	8	391	5.8e-91	299.6	COG2814	Predicted arabinose efflux permease, MFS family	394
2918250710	858	93.79	2	850	45	950	0.0e+00	631.8	COG0474	Magnesium-transporting ATPase (P-type)	917
2918250711	269	90.53	1	269	11	316	2.3e-46	153.7	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2918250712	124	91.73	2	119	7	128	1.6e-22	74.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918250713	462	89.27	238	462	5	237	6.5e-40	57.6	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
2918250713	462	93.1	3	237	2	244	6.5e-40	68.1	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
2918250715	405	94.24	25	405	17	392	3.7e-55	182.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918250716	330	89.85	4	323	7	307	1.0e-30	101.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918250717	261	91.96	23	244	3	208	1.2e-54	179.9	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2918250718	319	76.69	58	319	67	316	7.9e-68	223.2	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918250719	374	95.92	14	366	14	342	1.5e-73	242.5	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918250720	345	77.01	15	342	67	324	3.3e-39	129.5	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918250721	283	97.61	17	250	3	247	1.3e-75	248.7	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918250722	268	94.96	8	265	12	256	1.7e-84	277.8	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918250723	302	96.68	8	297	2	292	2.0e-50	166.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918250724	327	92.54	8	326	16	325	7.4e-54	177.8	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918250725	280	11.76	15	48	5	24	6.3e-08	3	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
2918250725	280	62.35	141	268	55	160	6.3e-08	21.7	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
2918250726	292	95.82	3	284	4	278	2.3e-59	195.6	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2918250727	344	96.72	5	344	6	329	1.0e-30	101.8	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918250728	535	42.11	273	360	17	64	2.9e-43	29.4	COG0607	Rhodanese-related sulfurtransferase	110
2918250728	535	85.09	8	110	12	108	2.9e-43	34.7	COG0607	Rhodanese-related sulfurtransferase	110
2918250728	535	92.11	383	484	6	110	2.9e-43	17.1	COG0607	Rhodanese-related sulfurtransferase	110
2918250728	535	92.98	128	237	7	112	2.9e-43	52.1	COG0607	Rhodanese-related sulfurtransferase	110
2918250729	209	96.34	7	201	7	190	4.3e-52	171.5	COG5553	Predicted metal-dependent enzyme of the double-stranded beta helix superfamily	191
2918250730	264	96.81	15	263	3	245	9.5e-90	295.1	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918250731	350	94.57	91	347	12	255	2.9e-46	152.1	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918250732	208	92.59	21	206	8	207	2.1e-24	81	COG0778	Nitroreductase	207
2918250733	444	97.72	4	442	9	436	1.1e-118	391.3	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
2918250736	496	94.27	89	492	3	413	7.6e-110	361.9	COG0213	Thymidine phosphorylase	435
2918250737	537	98.86	3	463	2	433	4.4e-106	349.5	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
2918250738	335	74.43	1	274	13	274	3.1e-24	79.8	COG1566	Multidrug resistance efflux pump	352
2918250739	920	74.84	267	518	4	232	0.0e+00	269	COG1131	ABC-type multidrug transport system, ATPase component	293
2918250739	920	75.82	1	255	2	233	0.0e+00	234.7	COG1131	ABC-type multidrug transport system, ATPase component	293
2918250739	920	84.64	608	920	43	290	1.9e-23	78	COG0842	ABC-type multidrug transport system, permease component	286
2918250740	375	91.47	85	372	21	288	9.6e-26	85.5	COG0842	ABC-type multidrug transport system, permease component	286
2918250741	217	34.52	1	70	129	196	1.3e-37	36.8	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918250741	217	76.14	60	215	46	195	1.3e-37	92.2	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918250743	764	84.54	1	612	109	726	0.0e+00	555.7	COG2217	Cation transport ATPase	713
2918250744	186	96.13	10	186	6	179	1.0e-46	153.4	COG3038	Cytochrome b561	181
2918250746	190	86.99	12	188	20	146	1.0e-35	116.8	COG0071	Molecular chaperone IbpA, HSP20 family	146
2918250747	151	64.75	1	146	41	130	2.2e-08	29.1	COG5622	Protein required for attachment to host cells	139
2918250748	104	59.15	3	104	45	141	1.8e-11	39.2	COG2010	Cytochrome c, mono- and diheme variants	150
2918250749	280	84.86	46	251	32	216	5.8e-33	108.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918250751	285	47.8	139	285	81	156	7.5e-17	41.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918250751	285	77.36	1	154	5	127	7.5e-17	15.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918250752	570	91.23	214	568	15	222	1.1e-41	136.9	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918250753	279	77.99	1	124	4	127	3.7e-21	25.4	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918250753	279	79.87	152	279	30	156	3.7e-21	50.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918250754	909	93.48	4	907	46	948	0.0e+00	774.7	COG0474	Magnesium-transporting ATPase (P-type)	917
2918250756	297	15.09	5	76	41	75	8.0e-50	24.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918250756	297	91.81	68	297	13	225	8.0e-50	142.1	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918250757	384	77.85	1	377	15	383	2.4e-56	186	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
2918250758	227	87.28	2	212	17	215	8.1e-66	216.4	COG0765	ABC-type amino acid transport system, permease component	222
2918250759	217	92.54	2	216	17	227	9.4e-68	222.8	COG0765	ABC-type amino acid transport system, permease component	222
2918250760	248	97.93	9	247	2	238	8.2e-102	333.9	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918250761	261	96.82	1	260	2	275	2.9e-54	178.9	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918250762	336	99.72	1	336	1	352	7.7e-88	289.2	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918250763	507	22.36	5	106	146	234	0.0e+00	11.5	COG2721	Altronate dehydratase	381
2918250763	507	99.25	103	507	4	398	0.0e+00	534.9	COG2721	Altronate dehydratase	381
2918250765	251	94.16	3	242	3	244	1.0e-59	196.5	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
2918250766	244	97.45	1	244	1	229	1.9e-79	261.2	COG1489	DNA-binding protein, stimulates sugar fermentation	235
2918250767	250	95.48	1	239	14	309	3.7e-83	273.9	COG0024	Methionine aminopeptidase	255
2918250768	287	97.32	59	287	7	224	4.3e-69	226.9	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
2918250769	137	90.37	1	130	6	127	2.2e-26	87.1	COG3791	Uncharacterized conserved protein	133
2918250770	1080	30.28	64	243	48	186	7.6e-34	50	COG4564	Signal transduction histidine kinase	459
2918250770	1080	30.72	228	413	77	217	7.6e-34	59.7	COG4564	Signal transduction histidine kinase	459
2918250770	1080	64.71	538	1077	214	642	2.4e-112	370.2	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918250771	431	99.54	1	431	1	437	0.0e+00	558.2	COG0015	Adenylosuccinate lyase	438
2918250772	118	91.58	24	117	6	92	1.3e-31	102.8	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
2918250773	106	99.04	1	106	1	103	1.0e-32	107.3	COG5467	Uncharacterized protein	104
2918250775	254	93.09	1	247	8	263	9.4e-82	268.8	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
2918250776	80	95.18	1	80	2	80	3.4e-35	114.8	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
2918250777	208	65.05	2	204	97	284	1.0e-51	170.6	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
2918250778	229	98.6	4	217	3	213	2.8e-69	227.7	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
2918250779	408	98.79	5	407	3	409	1.9e-96	318.1	COG0004	Ammonia channel protein AmtB	409
2918250780	229	98.36	1	229	3	242	4.4e-81	266.4	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
2918250781	745	96.04	2	736	9	735	0.0e+00	851.1	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
2918250782	79	94.44	1	79	1	85	8.0e-25	81.7	COG0271	Stress-induced morphogen (activity unknown)	90
2918250783	113	98.1	3	106	2	104	6.0e-46	149.3	COG0278	Glutaredoxin-related protein	105
2918250784	306	98.31	8	301	4	293	9.7e-95	311.8	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
2918250785	214	94.26	14	213	8	204	9.3e-22	73.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918250786	372	98.9	6	372	3	361	2.6e-112	370.3	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918250788	218	96.54	6	218	5	227	4.1e-16	54.2	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
2918250789	68	50	7	63	13	60	1.2e-06	23.1	COG4197	DNA-binding transcriptional regulator YdaS, prophage-encoded, Cro superfamily	96
2918250792	338	99.39	18	338	2	327	4.9e-101	332.7	COG0142	Geranylgeranyl pyrophosphate synthase	322
2918250793	58	16.67	5	57	37	77	2.7e-03	11.7	COG4669	Type III secretory pathway, lipoprotein EscJ	246
2918250794	256	93.55	14	255	14	245	1.3e-54	179.5	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
2918250795	287	71.56	7	284	62	290	3.0e-68	225.1	COG0616	Periplasmic serine protease, ClpP class	317
2918250796	263	94.59	1	263	7	251	2.0e-42	139.8	COG0730	Uncharacterized membrane protein YfcA	258
2918250797	239	62.75	15	207	67	194	8.2e-19	62.4	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
2918250798	721	59.34	580	708	11	118	6.5e-08	26	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918250798	721	79.44	185	574	80	392	1.8e-61	203.2	COG0642	Signal transduction histidine kinase	336
2918250801	294	99.3	9	291	2	285	2.4e-105	346.5	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918250802	603	99.32	25	600	3	590	0.0e+00	560	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918250803	74	93.33	1	74	1	70	2.0e-26	86.8	COG0254	Ribosomal protein L31	75
2918250804	144	72	2	143	24	149	3.5e-26	86.4	COG5317	Uncharacterized protein	175
2918250805	162	94.52	1	139	8	145	3.5e-35	115.6	COG0071	Molecular chaperone IbpA, HSP20 family	146
2918250806	642	82.74	235	633	63	388	1.1e-69	229.9	COG0642	Signal transduction histidine kinase	336
2918250807	267	97.63	1	265	6	293	9.0e-44	144.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918250808	441	98.59	2	438	6	426	0.0e+00	620.1	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
2918250809	383	94.31	3	373	2	349	4.7e-95	313.4	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
2918250810	305	92.78	46	305	12	255	8.3e-91	298.8	COG3931	Predicted N-formylglutamate amidohydrolase	263
2918250812	251	95.85	8	241	5	235	1.9e-60	198.7	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918250813	215	99.46	1	214	1	184	2.7e-67	221.2	COG0563	Adenylate kinase or related kinase	178
2918250814	446	96.59	8	441	12	436	0.0e+00	519.5	COG0201	Preprotein translocase subunit SecY	436
2918250815	162	98.05	2	154	2	152	1.8e-41	136.5	COG0200	Ribosomal protein L15	152
2918250816	63	94.55	7	61	3	54	2.5e-25	82.7	COG1841	Ribosomal protein L30/L7E	55
2918250817	189	91.85	2	180	14	182	5.2e-70	229.1	COG0098	Ribosomal protein S5	181
2918250818	120	93.65	1	120	9	126	3.8e-43	141.7	COG0256	Ribosomal protein L18	125
2918250819	177	98.88	1	177	1	177	2.4e-66	217.5	COG0097	Ribosomal protein L6P/L9E	178
2918250820	132	100	1	132	1	133	6.2e-49	160	COG0096	Ribosomal protein S8	132
2918250821	101	96.72	41	101	3	61	3.7e-27	89	COG0199	Ribosomal protein S14	61
2918250822	180	98.33	2	180	2	178	1.1e-81	267.4	COG0094	Ribosomal protein L5	180
2918250823	105	98.15	1	104	2	107	1.5e-32	106.8	COG0198	Ribosomal protein L24	104
2918250824	122	100	1	122	1	123	7.4e-59	191.9	COG0093	Ribosomal protein L14	122
2918250825	84	83.91	1	81	7	79	8.7e-37	119.8	COG0186	Ribosomal protein S17	87
2918250826	68	97.06	1	66	1	66	2.7e-29	95.8	COG0255	Ribosomal protein L29	69
2918250827	143	93.29	1	142	2	140	1.9e-58	191.1	COG0197	Ribosomal protein L16/L10AE	146
2918250828	249	98.28	12	248	1	229	3.3e-96	315.7	COG0092	Ribosomal protein S3	233
2918250829	131	94.63	3	125	7	147	1.4e-34	113.5	COG0091	Ribosomal protein L22	120
2918250830	92	98.92	1	92	1	92	7.2e-40	129.6	COG0185	Ribosomal protein S19	93
2918250831	275	99.64	1	274	1	274	3.0e-125	411.8	COG0090	Ribosomal protein L2	275
2918250832	92	97.87	1	92	1	92	4.5e-35	114.9	COG0089	Ribosomal protein L23	94
2918250833	206	97.7	1	206	2	213	2.1e-65	214.8	COG0088	Ribosomal protein L4	214
2918250834	236	97.8	2	215	2	223	2.7e-78	257.5	COG0087	Ribosomal protein L3	218
2918250835	102	98.08	1	102	1	102	1.8e-48	157.7	COG0051	Ribosomal protein S10	104
2918250836	396	100	1	396	1	394	0.0e+00	736.3	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2918250837	692	98.08	1	692	8	722	0.0e+00	864.9	COG0480	Translation elongation factor EF-G, a GTPase	697
2918250838	156	99.32	2	149	2	148	3.3e-64	209.7	COG0049	Ribosomal protein S7	148
2918250839	123	95.35	1	123	7	129	3.0e-64	209.1	COG0048	Ribosomal protein S12	129
2918250840	237	55.69	1	187	6	186	2.5e-36	119.7	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918250841	1390	5.06	875	934	407	447	0.0e+00	12.3	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2918250841	1390	19.48	1117	1368	593	750	0.0e+00	24.7	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2918250841	1390	99.38	14	843	4	809	0.0e+00	1002.5	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2918250842	1374	97.33	1	1373	26	1082	0.0e+00	1494.3	COG0085	DNA-directed RNA polymerase, beta subunit/140 kD subunit	1060
2918250843	124	98.4	1	124	3	125	2.6e-49	161.6	COG0222	Ribosomal protein L7/L12	124
2918250844	173	96.02	2	171	5	173	5.5e-49	160.7	COG0244	Ribosomal protein L10	175
2918250845	237	99.57	1	227	1	229	4.5e-98	322.1	COG0081	Ribosomal protein L1	228
2918250846	144	99.29	2	144	1	140	2.3e-60	197.4	COG0080	Ribosomal protein L11	141
2918250847	176	99.45	1	176	1	182	5.3e-68	223.1	COG0250	Transcription antitermination factor NusG	178
2918250848	65	73.97	1	59	19	72	8.9e-21	68.1	COG0690	Preprotein translocase subunit SecE	73
2918250850	396	100	1	396	1	394	0.0e+00	736.3	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2918250853	287	92.4	18	287	18	260	4.1e-67	220.9	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2918250856	193	69.88	11	193	33	206	1.9e-40	133.4	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918250857	425	84.4	2	425	71	465	1.6e-63	209.8	COG5338	Uncharacterized protein	468
2918250858	147	92.48	15	147	5	127	1.3e-24	81.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918250859	412	93.72	24	393	8	350	1.4e-52	173.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918250860	614	89.78	1	294	30	319	1.7e-89	85.3	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918250860	614	96.28	307	609	9	319	1.7e-89	215.9	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918250861	250	98.03	2	248	5	253	4.6e-80	263.2	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918250862	237	99.16	3	237	2	236	3.8e-89	292.6	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918250863	79	16.79	12	79	35	81	2.7e-03	12.2	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2918250864	272	77.61	14	271	16	223	1.5e-46	153.5	COG1877	Trehalose-6-phosphatase	266
2918250867	302	95.48	2	302	6	301	2.7e-73	241.4	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918250869	544	48.23	436	541	65	132	7.4e-05	15.5	COG4642	Uncharacterized conserved protein	139
2918250872	286	97.61	29	285	3	247	1.5e-93	307.5	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918250873	292	88.37	30	292	26	253	6.2e-58	191.1	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918250874	378	94.96	122	376	12	256	1.3e-62	206.5	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918250875	109	25.82	6	104	36	98	1.0e-03	13.2	COG2114	Adenylate cyclase, class 3	227
2918250876	257	96.81	1	251	5	247	2.5e-84	277.3	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918250877	275	94.19	25	275	12	254	1.3e-69	229.2	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918250878	343	94.63	1	342	6	322	1.8e-40	133.8	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918250880	320	99.58	72	310	1	238	2.1e-112	369	COG1186	Protein chain release factor B	239
2918250881	478	91.36	2	431	5	395	1.4e-93	308.5	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
2918250883	831	96.23	1	803	2	766	0.0e+00	944.6	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
2918250884	449	89.47	96	442	27	264	2.6e-66	218.3	COG0860	N-acetylmuramoyl-L-alanine amidase	231
2918250885	989	97.96	2	598	2	480	0.0e+00	737.5	COG1530	Ribonuclease G or E	487
2918250887	184	99.34	32	183	1	151	1.6e-47	156	COG0782	Transcription elongation factor, GreA/GreB family	151
2918250888	292	93.01	6	284	11	263	3.6e-55	181.6	COG3741	N-formylglutamate amidohydrolase	272
2918250889	317	37.88	15	252	39	163	1.4e-13	44.9	COG3608	Predicted deacylase	331
2918250890	176	95.15	8	174	8	164	5.9e-58	189.6	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
2918250891	396	95.28	42	396	7	349	1.2e-68	226.3	COG0628	Predicted PurR-regulated permease PerM	355
2918250892	295	87.34	1	289	37	305	4.6e-56	184.8	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918250893	193	50.81	18	191	87	212	7.9e-53	174.6	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
2918250894	149	91.19	2	149	13	157	8.9e-37	120.5	COG2030	Acyl dehydratase	159
2918250895	313	99.67	1	311	1	306	4.5e-103	339.2	COG0196	FAD synthase	304
2918250896	745	66.97	265	742	202	645	1.0e-105	348.7	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918250897	1252	98.56	24	978	3	754	0.0e+00	523.3	COG0209	Ribonucleotide reductase alpha subunit	696
2918250900	138	27.35	5	135	179	277	6.6e-08	26.7	COG0349	Ribonuclease D	361
2918250902	101	86.32	1	101	4	104	1.8e-16	54.7	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918250903	425	73.91	87	407	65	336	1.1e-34	114.5	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2918250905	156	31.46	78	155	21	76	1.6e-11	32	COG1633	Rubrerythrin	176
2918250905	156	39.89	7	96	29	99	1.6e-11	10.2	COG1633	Rubrerythrin	176
2918250906	863	94.03	2	862	52	870	0.0e+00	728.1	COG1643	HrpA-like RNA helicase	845
2918250909	214	20.08	2	64	3	55	3.1e-34	64.5	COG1192	Cellulose biosynthesis protein BcsQ	259
2918250909	214	53.41	60	214	117	257	3.1e-34	47.8	COG1192	Cellulose biosynthesis protein BcsQ	259
2918250910	335	93.4	9	224	13	210	8.0e-75	244.8	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
2918250911	479	99.15	17	479	3	467	2.0e-124	410.6	COG0277	FAD/FMN-containing dehydrogenase	459
2918250912	468	99.3	2	468	3	428	0.0e+00	647	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
2918250913	117	96.43	2	117	5	112	5.7e-47	153.1	COG2824	Uncharacterized Zn-ribbon-containing protein	112
2918250914	436	97.67	132	434	4	297	3.4e-75	247.9	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918250915	245	91.76	1	245	1	245	4.1e-79	260.4	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
2918250916	323	99.35	4	310	2	307	9.7e-119	390.8	COG0223	Methionyl-tRNA formyltransferase	307
2918250917	170	99.41	1	167	1	168	6.3e-64	209.2	COG0242	Peptide deformylase	168
2918250919	599	97.74	15	461	7	396	4.3e-106	350.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918250920	436	98.42	17	433	7	379	1.5e-92	304.9	COG1454	Alcohol dehydrogenase, class IV	377
2918250921	907	91.55	22	906	74	929	2.0e-110	365.1	COG5373	Uncharacterized membrane protein	931
2918250922	255	93.61	8	255	2	250	2.6e-54	179.3	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
2918250923	323	93.77	2	312	12	297	6.3e-55	181	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2918250924	235	93.25	7	233	8	228	3.0e-38	126.4	COG1183	Phosphatidylserine synthase	234
2918250925	458	99.5	15	438	2	400	1.3e-88	292.3	COG0247	Fe-S oxidoreductase	388
2918250926	400	91.47	4	399	37	465	3.7e-49	162.4	COG0277	FAD/FMN-containing dehydrogenase	459
2918250927	495	99.57	20	471	2	468	5.6e-125	412.4	COG0277	FAD/FMN-containing dehydrogenase	459
2918250928	41	100	1	41	1	38	3.9e-20	66.3	COG0257	Ribosomal protein L36	38
2918250929	222	93.87	2	216	10	208	9.0e-64	209.6	COG0684	Regulator of RNase E activity RraA	210
2918250933	343	98.51	1	343	3	332	8.0e-36	118.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918250934	270	96.81	3	262	3	245	1.3e-86	284.8	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918250935	258	94.96	1	254	11	255	9.7e-74	242.7	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918250936	391	83.66	2	371	21	363	5.9e-45	148.1	COG4645	Uncharacterized protein	410
2918250937	1190	65.74	345	660	130	388	9.1e-73	240.8	COG0642	Signal transduction histidine kinase	336
2918250937	1190	91.73	669	805	6	127	4.7e-62	72	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918250937	1190	93.98	820	1038	5	129	4.7e-62	130.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918250937	1190	97.88	18	259	5	235	2.1e-58	191.6	COG3300	MHYT domain, NO-binding membrane sensor	236
2918250938	365	97.03	1	365	9	367	8.4e-129	424.4	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2918250940	236	91.11	9	235	9	213	2.9e-79	260.1	COG0321	Lipoate-protein ligase B	221
2918250942	465	95.72	1	465	15	484	0.0e+00	511.3	COG0380	Trehalose-6-phosphate synthase	486
2918250943	329	97.81	3	326	5	317	2.2e-113	372.9	COG0837	Glucokinase	320
2918250944	897	99.49	10	889	2	784	0.0e+00	791	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
2918250945	352	69.55	12	336	84	364	2.7e-35	116.8	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918250946	576	96.48	28	576	14	561	2.4e-129	426.8	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918250947	101	84.95	10	98	5	83	5.5e-25	82.3	COG1254	Acylphosphatase	92
2918250950	265	97.33	4	264	5	259	1.8e-107	352.8	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
2918250951	71	94.12	4	71	5	68	9.0e-17	55.8	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
2918250952	393	97.68	17	392	6	384	4.2e-69	228.2	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918250954	471	97.14	29	471	10	450	0.0e+00	484.7	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
2918250955	100	72.65	1	100	16	100	3.3e-10	34.6	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918250957	108	99.03	4	106	1	102	1.6e-43	142.1	COG0261	Ribosomal protein L21	103
2918250958	94	97.7	1	87	1	85	1.3e-42	138.3	COG0211	Ribosomal protein L27	87
2918250959	441	92.84	1	347	1	337	0.0e+00	448.6	COG0536	GTPase involved in cell partioning and DNA repair	369
2918250960	385	98.65	12	385	5	369	0.0e+00	454.1	COG0263	Glutamate 5-kinase	369
2918250961	222	95.48	9	218	2	212	3.8e-46	152.3	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2918250962	247	96.14	1	247	5	253	2.5e-42	139.7	COG0730	Uncharacterized membrane protein YfcA	258
2918250963	424	99.04	11	424	4	416	0.0e+00	576.2	COG0014	Gamma-glutamyl phosphate reductase	417
2918250964	236	86.43	46	236	4	175	3.5e-41	135.9	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
2918250965	148	90.43	28	141	4	107	5.1e-38	123.9	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
2918250966	152	100	1	151	1	156	1.4e-46	153.2	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
2918250967	524	99.41	9	516	3	508	0.0e+00	676.4	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
2918250968	510	52.11	286	503	201	422	4.6e-79	178.1	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
2918250968	510	58.22	34	297	28	275	4.6e-79	90.4	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
2918250969	472	91.91	3	402	22	396	0.0e+00	442.5	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
2918250970	426	96.86	174	426	2	248	4.2e-61	200.5	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
2918250971	170	92.44	4	164	5	163	2.6e-19	64.4	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918250972	103	68.38	4	97	19	98	2.3e-07	25.2	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918250973	121	49.14	3	120	2	115	2.3e-34	113.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918250974	765	98.28	1	746	5	745	0.0e+00	685	COG0643	Chemotaxis protein histidine kinase CheA	716
2918250975	177	89.09	8	169	14	160	5.4e-46	150.8	COG0835	Chemotaxis signal transduction protein	165
2918250976	861	25.18	4	422	36	142	1.9e-105	8.4	COG0840	Methyl-accepting chemotaxis protein	408
2918250976	861	80.47	473	845	83	424	1.9e-105	340.4	COG0840	Methyl-accepting chemotaxis protein	408
2918250977	308	98.52	38	308	2	267	3.3e-78	257.3	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918250978	234	95.12	38	201	3	158	2.7e-46	151.6	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
2918250979	352	98.86	4	348	2	349	4.1e-123	405.5	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918250980	374	62.82	23	333	150	416	7.7e-28	91.1	COG0840	Methyl-accepting chemotaxis protein	408
2918250981	101	80.34	3	101	11	104	6.1e-17	56.1	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918250982	254	32.19	105	172	12	58	2.0e-08	15.6	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2918250982	254	44.52	186	251	64	128	2.0e-08	11.4	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2918250983	391	90.98	27	267	7	127	1.3e-37	123.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918250984	398	82.07	81	398	65	366	2.3e-37	123.3	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2918250985	134	96.67	14	133	3	118	8.5e-51	165.6	COG3536	Uncharacterized conserved protein, DUF971 family	120
2918250986	74	92.42	17	74	1	61	2.3e-24	79.7	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
2918250987	222	91.4	8	220	6	207	1.8e-52	173.2	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
2918250988	314	94.1	4	313	19	305	3.0e-102	336.9	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2918250989	188	96.34	23	186	5	162	3.9e-62	203.6	COG3760	Uncharacterized protein	164
2918250991	223	90.09	10	217	17	207	2.3e-49	162.4	COG0684	Regulator of RNase E activity RraA	210
2918250992	309	98.08	1	309	2	308	1.5e-45	150.3	COG0679	Predicted permease	311
2918250993	326	95.61	4	326	9	313	1.4e-83	275.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918250994	565	81.41	60	560	78	423	1.0e-56	185.9	COG0840	Methyl-accepting chemotaxis protein	408
2918250995	326	96.55	6	326	10	317	2.8e-87	287.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918250997	500	98.81	2	500	2	499	0.0e+00	669.1	COG3333	TctA family transporter	504
2918250998	459	99.57	2	459	2	464	0.0e+00	584.2	COG0215	Cysteinyl-tRNA synthetase	464
2918250999	447	96.88	1	445	11	475	1.5e-112	371.5	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2918251002	120	99.17	1	120	1	120	6.3e-38	124.3	COG3759	Uncharacterized membrane protein	121
2918251003	646	100	67	628	1	552	0.0e+00	826.6	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918251005	137	96.15	1	137	3	152	8.8e-44	140.9	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
2918251006	94	98.91	1	91	1	91	1.8e-23	77.6	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
2918251007	339	98.78	9	337	3	327	1.5e-109	360.9	COG0240	Glycerol-3-phosphate dehydrogenase	329
2918251008	201	99.07	1	201	1	213	1.3e-50	167	COG0625	Glutathione S-transferase	211
2918251009	360	99.71	1	352	1	349	0.0e+00	472.7	COG3839	ABC-type sugar transport system, ATPase component	338
2918251010	288	95.41	4	288	10	279	8.4e-86	282.5	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918251011	294	96.98	2	293	5	293	4.5e-83	273.7	COG1175	ABC-type sugar transport system, permease component	295
2918251012	446	98.65	1	440	5	441	3.6e-64	212.5	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918251013	509	84.52	8	367	58	390	1.1e-50	167.8	COG0642	Signal transduction histidine kinase	336
2918251013	509	93.23	379	507	7	130	9.6e-16	51.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918251014	260	89.43	24	258	4	206	1.8e-52	172.9	COG1451	Predicted metal-dependent hydrolase	223
2918251015	400	39.69	205	397	12	163	2.5e-32	7.4	COG0477	MFS family permease	338
2918251015	400	67.62	4	242	9	267	2.5e-32	100.8	COG0477	MFS family permease	338
2918251016	183	63.72	3	175	4	147	4.0e-42	139.1	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
2918251017	378	94.18	3	378	23	394	4.6e-107	352.7	COG0019	Diaminopimelate decarboxylase	394
2918251018	70	65.08	6	69	23	63	1.9e-15	51.2	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918251019	227	97.4	1	226	3	227	1.8e-29	98	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918251020	115	89.66	1	114	11	114	1.3e-35	116.6	COG3450	Predicted enzyme of the cupin superfamily	116
2918251022	204	100	1	204	1	210	1.2e-57	189.8	COG0522	Ribosomal protein S4 or related protein	205
2918251023	372	85.81	1	371	1	369	1.3e-91	301.9	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
2918251024	157	87.67	2	135	19	146	1.5e-34	113.5	COG0071	Molecular chaperone IbpA, HSP20 family	146
2918251025	75	31.76	5	40	6	32	3.9e-11	17.9	COG5568	Uncharacterized protein	85
2918251025	75	43.53	36	75	49	85	3.9e-11	18.8	COG5568	Uncharacterized protein	85
2918251027	141	70.27	3	123	26	129	2.7e-08	28.4	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
2918251028	137	92.91	8	137	8	125	2.6e-29	96.8	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2918251029	227	71.57	1	225	4	227	4.2e-75	247.8	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2918251030	343	53.06	181	311	34	111	2.0e-02	13.9	COG0511	Biotin carboxyl carrier protein	140
2918251031	219	18.18	2	62	3	50	2.9e-33	53.7	COG1192	Cellulose biosynthesis protein BcsQ	259
2918251031	219	51.89	63	218	116	252	2.9e-33	53.2	COG1192	Cellulose biosynthesis protein BcsQ	259
2918251032	1004	25.13	184	376	56	154	6.5e-60	6.5	COG0642	Signal transduction histidine kinase	336
2918251032	1004	85.53	401	840	54	390	6.5e-60	195.2	COG0642	Signal transduction histidine kinase	336
2918251032	1004	89.47	880	1004	8	126	8.1e-18	57.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918251033	218	66.54	16	213	20	188	4.5e-39	129.4	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2918251034	196	76.74	39	176	17	148	9.5e-12	39.5	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918251035	344	71.68	71	337	9	208	1.2e-09	33.3	COG0500	SAM-dependent methyltransferase	257
2918251036	896	99.43	8	896	4	868	0.0e+00	1314.4	COG1048	Aconitase A	861
2918251038	864	99.77	1	861	2	851	0.0e+00	1497.6	COG1049	Aconitase B	852
2918251039	164	77.83	1	164	11	175	8.1e-53	173.9	COG0684	Regulator of RNase E activity RraA	210
2918251040	191	81	5	179	9	170	1.4e-15	51.7	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
2918251042	243	73.77	8	228	58	237	1.0e-51	170.2	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
2918251044	528	73.61	20	458	70	426	1.3e-43	143.9	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918251045	258	92.46	4	250	15	198	4.8e-45	147.1	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918251046	170	26.67	9	147	102	205	1.1e-02	9.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918251047	205	96.15	1	202	3	202	2.1e-43	142.8	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2918251048	221	97.26	3	220	4	216	5.2e-31	102.4	COG4094	Uncharacterized membrane protein	219
2918251049	144	98.77	1	119	2	162	9.9e-29	95.4	COG0517	CBS domain	117
2918251051	248	94.03	20	86	3	65	5.6e-40	47.7	COG1278	Cold shock protein, CspA family	67
2918251051	248	97.01	182	248	2	66	5.6e-40	80.5	COG1278	Cold shock protein, CspA family	67
2918251054	290	94.02	1	288	11	293	2.4e-24	73.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918251055	835	50	582	733	20	120	2.1e-10	33.8	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918251055	835	71.07	93	570	112	391	3.3e-76	252.2	COG0642	Signal transduction histidine kinase	336
2918251056	322	85	16	289	12	232	1.8e-29	97.6	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918251057	234	98.73	1	234	3	236	1.1e-91	300.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918251058	274	98.82	20	272	4	254	9.9e-99	324.4	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918251059	315	95.67	6	310	9	317	5.6e-80	263.6	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918251060	291	99	1	290	3	300	5.2e-69	227.8	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918251061	384	98.36	20	384	2	361	1.9e-58	193	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918251062	318	97.94	16	313	3	287	4.5e-79	260.6	COG3327	DNA-binding transcriptional regulator PaaX (phenylacetic acid degradation)	291
2918251063	342	14.61	93	131	47	72	1.6e-03	3.2	COG1633	Rubrerythrin	176
2918251063	342	24.72	174	285	35	78	1.6e-03	7.6	COG1633	Rubrerythrin	176
2918251064	352	77.67	2	93	14	93	5.1e-15	49.3	COG0633	Ferredoxin	102
2918251064	352	85.82	100	349	6	235	2.6e-45	148.8	COG1018	Ferredoxin-NADP reductase	266
2918251065	338	97.44	4	336	7	272	6.1e-57	187.9	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918251066	374	86.18	2	374	52	419	2.6e-92	303.9	COG3508	Homogentisate 1,2-dioxygenase	427
2918251067	188	89.47	36	167	14	132	7.8e-22	72.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918251068	205	95.48	5	180	5	173	2.1e-55	181.6	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2918251069	562	97.2	24	408	3	384	1.2e-69	229.6	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918251072	421	98.77	7	406	4	405	2.1e-118	390.2	COG2081	Predicted flavoprotein YhiN	408
2918251073	742	92.43	65	736	17	675	0.0e+00	659.8	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2918251075	338	75.86	2	338	101	430	7.7e-108	355.8	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain	403
2918251077	223	98.23	1	222	1	222	2.7e-46	152.7	COG1842	Phage shock protein A	225
2918251078	75	19.44	1	30	81	101	1.8e-02	5.5	COG4062	Tetrahydromethanopterin S-methyltransferase, subunit B	108
2918251078	75	25.93	37	74	34	61	1.8e-02	3.9	COG4062	Tetrahydromethanopterin S-methyltransferase, subunit B	108
2918251079	137	89.86	15	82	4	65	1.2e-19	63.5	COG1983	Phage shock protein PspC (stress-responsive transcriptional regulator)	70
2918251083	630	99.52	1	630	4	627	0.0e+00	861.2	COG3158	K+ transporter	627
2918251084	440	87.88	5	273	30	261	3.5e-50	165.3	COG3455	Type VI protein secretion system component VasF	262
2918251085	669	54.07	30	666	13	656	0.0e+00	479.1	COG3523	Type VI protein secretion system component VasK	1188
2918251086	225	59.03	8	214	7	140	2.8e-32	106.9	COG3913	Uncharacterized protein	227
2918251088	205	97.67	1	205	1	210	4.2e-48	158.8	COG0625	Glutathione S-transferase	211
2918251089	393	98.47	1	392	4	390	0.0e+00	448.2	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2918251092	545	77.72	4	329	37	322	2.3e-24	80.9	COG0457	Tetratricopeptide (TPR) repeat	291
2918251093	438	96.03	7	438	13	447	3.1e-119	393.2	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
2918251095	534	99.81	16	534	2	515	0.0e+00	740.5	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
2918251096	550	95.76	6	548	23	564	1.2e-126	418	COG5360	Uncharacterized conserved protein, heparinase superfamily	566
2918251097	432	99.44	95	431	2	357	1.5e-85	282.4	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
2918251098	861	99.25	5	858	1	799	0.0e+00	1156.6	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918251099	188	83.56	47	183	8	129	8.1e-18	59.2	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2918251100	257	74.44	1	257	3	203	1.4e-20	66.8	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
2918251102	283	97.91	1	281	2	282	4.9e-76	250.2	COG2890	Methylase of polypeptide chain release factors	280
2918251103	357	98.07	1	357	5	360	0.0e+00	521.8	COG0216	Protein chain release factor A	363
2918251104	438	95.65	4	413	2	397	5.0e-88	290.2	COG0373	Glutamyl-tRNA reductase	414
2918251105	376	98.65	9	369	3	367	0.0e+00	478.8	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
2918251106	411	41.92	17	144	3	124	4.7e-29	83.9	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
2918251106	411	48.11	161	360	136	275	4.7e-29	10.8	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
2918251107	763	98.41	16	763	5	748	0.0e+00	903.9	COG3605	Signal transduction protein containing GAF and PtsI domains	756
2918251108	368	95.94	20	345	10	340	1.4e-60	199.9	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2918251109	411	99.77	1	409	1	442	0.0e+00	479.3	COG0527	Aspartokinase	447
2918251110	259	94.67	10	259	11	241	3.8e-90	296	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2918251112	181	89.5	1	181	17	195	2.6e-26	87	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
2918251113	152	96.71	1	149	4	150	1.7e-40	132.9	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
2918251114	197	92.73	1	111	1	102	9.7e-26	82.4	COG1544	Ribosome-associated translation inhibitor RaiA	110
2918251115	518	96.65	1	514	15	447	0.0e+00	510.1	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
2918251116	258	98.35	19	258	5	243	4.5e-113	371	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
2918251117	296	54.34	24	148	30	123	7.8e-20	26.2	COG1934	Lipopolysaccharide export system protein LptA	173
2918251117	296	74.57	134	282	37	165	7.8e-20	42.1	COG1934	Lipopolysaccharide export system protein LptA	173
2918251118	253	88.43	41	246	22	212	9.2e-27	88.4	COG5375	Uncharacterized protein	216
2918251119	343	98.02	31	229	4	201	4.0e-73	239.3	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
2918251120	208	52.21	5	208	13	201	2.8e-69	228.8	COG0349	Ribonuclease D	361
2918251122	323	95.65	6	288	3	266	1.8e-55	182.9	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2918251123	388	47.78	197	387	8	190	3.3e-08	17.3	COG0477	MFS family permease	338
2918251123	388	53	10	216	9	211	3.3e-08	13.2	COG0477	MFS family permease	338
2918251124	266	97.8	1	266	5	271	1.3e-91	301.5	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
2918251125	488	99.13	24	480	2	455	0.0e+00	491.8	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2918251126	1515	92.11	1214	1504	4	283	5.1e-99	325.8	COG0070	Glutamate synthase domain 3	301
2918251126	1515	98.98	724	1209	4	487	0.0e+00	650.6	COG0069	Glutamate synthase domain 2	485
2918251126	1515	99.19	25	407	3	371	1.6e-127	419.9	COG0067	Glutamate synthase domain 1	371
2918251127	151	75.93	6	138	33	155	4.0e-10	35	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918251128	483	59.24	1	308	121	338	5.7e-12	39.7	COG0457	Tetratricopeptide (TPR) repeat	291
2918251129	222	95.35	2	213	2	206	2.1e-42	140	COG0625	Glutathione S-transferase	211
2918251131	627	99.36	1	627	3	624	0.0e+00	763.1	COG0326	Molecular chaperone, HSP90 family	623
2918251132	400	71.83	39	399	107	389	6.5e-71	233.6	COG0642	Signal transduction histidine kinase	336
2918251133	144	93.79	1	142	6	141	1.9e-42	139.3	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2918251135	238	83.02	32	237	6	181	6.5e-29	95.4	COG0560	Phosphoserine phosphatase	212
2918251136	133	68.42	14	133	7	97	9.6e-06	19.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918251137	310	84.41	21	188	19	175	4.4e-32	105.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918251138	149	73.66	2	142	43	179	1.4e-31	104.7	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918251140	155	97.16	14	155	5	141	1.9e-17	57.2	COG2210	Peroxiredoxin family protein	137
2918251141	271	97.7	5	259	4	258	1.5e-85	281.1	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
2918251143	319	99.34	10	313	2	301	1.8e-121	399.5	COG0031	Cysteine synthase	300
2918251144	151	91.33	2	148	2	138	1.3e-32	107.6	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918251145	529	98.17	58	522	8	490	1.4e-106	351.8	COG1793	ATP-dependent DNA ligase	444
2918251146	363	90.62	12	349	20	415	2.4e-52	171.6	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
2918251147	309	95.48	1	305	13	308	0.0e+00	431.1	COG2313	Pseudouridine-5'-phosphate glycosidase (pseudoU degradation)	310
2918251149	182	79.5	1	181	10	168	5.6e-19	63.1	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
2918251150	171	91.16	2	170	14	178	2.2e-07	24.1	COG5342	Invasion protein IalB, involved in pathogenesis	181
2918251151	285	98.57	6	285	3	278	9.0e-96	315.4	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2918251152	148	93.97	4	119	7	115	1.6e-30	100	COG3450	Predicted enzyme of the cupin superfamily	116
2918251153	217	73.87	27	216	48	194	3.4e-31	103.8	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918251154	345	96.69	1	343	9	329	3.4e-86	284.2	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918251155	298	77.71	3	294	67	331	1.7e-83	275.5	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918251156	173	96.32	1	133	4	134	5.0e-41	134.7	COG0864	Metal-responsive transcriptional regulator, contains CopG/Arc/MetJ DNA-binding domain	136
2918251157	523	96.37	1	518	8	564	5.4e-111	366.9	COG0747	ABC-type transport system, periplasmic component	556
2918251158	314	99.37	1	310	1	316	5.2e-111	365.8	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918251159	286	92.95	2	283	19	295	3.2e-91	299.9	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918251160	260	46.2	2	258	6	260	1.0e-67	223.6	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918251161	267	97.25	2	262	4	251	6.6e-76	249.8	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
2918251163	741	6.57	20	172	67	112	9.0e-20	15.1	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
2918251163	741	17	224	421	299	417	9.0e-20	12.7	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
2918251163	741	38.43	465	741	432	700	9.0e-20	34.7	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
2918251165	166	96.99	3	166	2	162	1.5e-58	192.1	COG1329	RNA polymerase-interacting regulator, CarD/CdnL/TRCF family	166
2918251166	109	91.78	1	65	3	69	1.9e-17	57.8	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2918251167	309	98.34	1	290	1	296	1.1e-61	204	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918251168	411	96.08	1	399	8	375	4.8e-08	24.3	COG0477	MFS family permease	338
2918251169	136	92.64	1	122	12	162	1.8e-25	84.9	COG0517	CBS domain	117
2918251170	250	96.48	1	244	7	253	1.4e-78	258.4	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918251171	132	88	5	106	7	94	8.9e-30	97.7	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
2918251172	846	61.35	57	502	2	320	2.9e-20	66.7	COG0513	Superfamily II DNA and RNA helicase	513
2918251173	280	60.87	4	276	121	344	8.3e-12	40.5	COG0457	Tetratricopeptide (TPR) repeat	291
2918251174	299	93.77	1	291	3	303	1.9e-22	73.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918251176	377	100	1	377	1	365	1.6e-114	377.6	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
2918251177	392	99.17	8	391	2	361	4.7e-93	306.7	COG1195	Recombinational DNA repair ATPase RecF	363
2918251178	823	99.53	6	823	3	640	0.0e+00	953.4	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
2918251179	62	19.5	1	59	257	319	5.4e-12	40.4	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918251180	261	99.63	1	260	1	267	3.0e-70	231.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918251181	473	79.93	4	469	111	556	0.0e+00	472.2	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
2918251182	215	98.07	2	208	2	204	5.5e-80	262.7	COG2039	Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)	207
2918251183	290	77.13	2	288	65	327	6.8e-88	290	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918251184	144	100	1	126	1	121	7.2e-07	20.4	COG1433	Predicted Fe-Mo cluster-binding protein, NifX family	121
2918251185	232	93.86	20	232	8	221	6.9e-45	147.6	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918251186	357	95.88	2	348	12	337	1.6e-46	153.1	COG4246	Uncharacterized protein	340
2918251187	320	96.17	4	312	5	305	3.3e-38	126.2	COG0679	Predicted permease	311
2918251188	634	70.4	282	632	112	375	2.0e-50	167	COG4585	Signal transduction histidine kinase	365
2918251190	231	97.63	16	229	1	206	1.9e-67	221.5	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918251191	637	93.94	280	633	13	353	1.0e-103	341.5	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
2918251191	637	97.48	1	270	3	273	1.9e-44	147	COG1082	Sugar phosphate isomerase/epimerase	274
2918251192	278	95.42	5	277	4	274	3.0e-55	181.9	COG0169	Shikimate 5-dehydrogenase	283
2918251193	378	87.43	5	357	6	325	7.2e-53	174.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918251194	291	99	1	290	2	299	8.4e-69	227.1	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918251195	340	96.28	1	311	10	320	2.6e-74	245.1	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918251196	247	98.82	1	247	3	253	9.2e-86	281.9	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918251197	254	99.16	9	245	2	236	1.0e-76	251.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918251198	228	84.68	12	225	5	192	1.0e-21	72.5	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918251199	306	95.68	15	305	8	295	5.6e-44	145.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918251200	349	88.18	1	347	10	315	2.0e-83	274.8	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2918251201	413	98.8	10	412	4	416	1.6e-60	200	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918251202	331	99.35	1	328	1	307	3.1e-70	230.9	COG1893	Ketopantoate reductase	307
2918251203	550	98.73	1	535	4	548	0.0e+00	668.9	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918251204	285	95.3	1	283	13	296	5.8e-94	309.1	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918251205	326	98.11	1	326	5	316	3.6e-115	379.5	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918251206	548	97.58	15	547	9	572	4.6e-109	360.4	COG0747	ABC-type transport system, periplasmic component	556
2918251207	258	90.62	16	243	5	207	4.6e-53	174.7	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2918251208	440	98.33	20	437	7	417	4.2e-83	274.4	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918251209	315	98.34	18	315	1	296	8.6e-56	184.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918251210	291	86.02	8	291	2	284	1.3e-115	380.9	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918251212	526	99.61	1	526	1	513	0.0e+00	634.5	COG3283	Transcriptional regulator of aromatic amino acids metabolism	511
2918251213	438	96.65	1	423	5	379	9.5e-87	286.3	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918251216	1148	99.39	2	1148	6	1147	0.0e+00	1803.2	COG1038	Pyruvate carboxylase	1149
2918251217	229	97.76	2	229	3	220	5.1e-36	119.3	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
2918251218	477	98.48	6	469	6	458	0.0e+00	547.1	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
2918251219	255	60.85	3	255	155	398	1.4e-64	213.1	COG0247	Fe-S oxidoreductase	388
2918251220	957	94.26	534	940	8	385	4.0e-48	154.9	COG0247	Fe-S oxidoreductase	388
2918251220	957	99.15	12	521	2	466	2.3e-97	320.2	COG0277	FAD/FMN-containing dehydrogenase	459
2918251221	569	100	13	567	1	527	0.0e+00	705.4	COG1620	L-lactate permease	522
2918251223	256	96.68	1	238	6	238	1.4e-55	182.9	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918251224	474	98.29	7	474	4	462	0.0e+00	528.9	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918251225	978	51.2	874	976	45	108	4.9e-05	16.5	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918251225	978	90.23	568	698	6	125	1.2e-55	60.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918251225	978	91.73	714	840	7	128	1.2e-55	123.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918251225	978	92.13	138	564	29	391	2.5e-77	255.7	COG0642	Signal transduction histidine kinase	336
2918251227	928	99.67	8	928	4	913	0.0e+00	1127.2	COG2352	Phosphoenolpyruvate carboxylase	910
2918251228	237	93.49	2	223	2	202	7.0e-13	42.5	COG0625	Glutathione S-transferase	211
2918251229	277	93.37	77	276	6	188	1.6e-76	250.6	COG1045	Serine acetyltransferase	194
2918251230	326	80.3	170	307	20	125	7.2e-19	62	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918251231	402	99.49	10	398	2	392	2.0e-66	219.7	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918251233	251	99.16	20	247	3	237	6.0e-79	259.2	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918251234	252	99.61	1	247	2	254	3.8e-85	279.9	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918251235	342	94.12	22	332	16	319	1.2e-72	239.4	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918251236	289	98.01	1	289	2	296	2.8e-72	238.5	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918251237	394	95.9	10	387	6	356	3.2e-51	169.1	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918251238	292	98.18	1	228	4	219	5.4e-62	203.6	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
2918251239	268	97.33	7	243	6	224	5.0e-64	210.5	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
2918251240	399	100	1	399	1	394	0.0e+00	471.6	COG0183	Acetyl-CoA acetyltransferase	392
2918251241	268	98.64	1	265	4	294	1.7e-49	163.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918251242	140	95.97	12	132	4	122	1.5e-33	110.4	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918251243	468	98.63	27	464	5	437	4.1e-126	415.9	COG0015	Adenylosuccinate lyase	438
2918251244	239	97.37	6	239	5	226	4.9e-70	230.2	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2918251245	182	88.16	1	182	27	227	1.3e-44	147.1	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2918251246	127	95.04	21	127	4	118	2.7e-20	64	COG1539	Dihydroneopterin aldolase	121
2918251247	345	84.16	1	264	28	282	5.4e-83	273.3	COG0863	DNA modification methylase	302
2918251248	224	93.56	32	223	2	190	5.3e-58	191.2	COG0164	Ribonuclease HII	199
2918251249	168	98.68	6	166	2	150	3.8e-51	167.9	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
2918251250	198	94.03	133	197	3	65	1.5e-50	87.2	COG1278	Cold shock protein, CspA family	67
2918251250	198	95.52	21	87	3	66	1.5e-50	74.8	COG1278	Cold shock protein, CspA family	67
2918251251	296	98.92	6	290	3	278	1.8e-86	284.5	COG0287	Prephenate dehydrogenase	279
2918251252	144	53.38	2	138	69	147	5.0e-02	4.4	COG2882	Flagellar biosynthesis chaperone FliJ	148
2918251253	445	96.38	3	441	15	440	0.0e+00	565.1	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
2918251254	246	99.57	1	225	1	231	1.7e-75	248	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918251255	69	98.51	1	69	1	66	2.8e-32	105.4	COG1278	Cold shock protein, CspA family	67
2918251258	280	95.19	3	268	2	258	1.5e-79	261.6	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918251259	365	97.44	1	365	5	347	9.0e-98	322.3	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918251260	121	84.21	1	119	5	116	4.7e-34	111.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918251261	166	88.48	8	166	10	155	8.5e-32	104.7	COG0835	Chemotaxis signal transduction protein	165
2918251262	925	14.59	657	785	616	725	0.0e+00	24.5	COG0643	Chemotaxis protein histidine kinase CheA	716
2918251262	925	20.56	1	222	6	160	0.0e+00	81.6	COG0643	Chemotaxis protein histidine kinase CheA	716
2918251262	925	52.52	184	652	348	743	0.0e+00	521.5	COG0643	Chemotaxis protein histidine kinase CheA	716
2918251262	925	64.29	793	925	10	126	3.7e-06	20.9	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918251264	217	90.65	3	217	17	210	3.9e-35	115.7	COG5385	Uncharacterized protein	214
2918251266	579	82.49	147	566	64	388	3.5e-79	262	COG0642	Signal transduction histidine kinase	336
2918251267	250	92.21	14	250	7	231	1.4e-64	212.1	COG3208	Surfactin synthase thioesterase subunit	244
2918251268	357	98.31	4	356	2	350	0.0e+00	492.2	COG1740	Ni,Fe-hydrogenase I small subunit	355
2918251269	604	99.65	16	604	2	564	0.0e+00	754.9	COG0374	Ni,Fe-hydrogenase I large subunit	545
2918251270	272	96.04	26	246	10	227	1.9e-77	254.3	COG1969	Ni,Fe-hydrogenase I cytochrome b subunit	227
2918251272	151	94.44	8	151	4	139	1.1e-37	124.3	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918251273	781	99.2	21	772	2	747	0.0e+00	742.8	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
2918251274	1029	47.41	657	792	2	111	1.0e-39	77.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918251274	1029	53.02	507	655	2	124	1.0e-39	51.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918251274	1029	81.73	96	500	67	388	3.5e-75	248.8	COG0642	Signal transduction histidine kinase	336
2918251274	1029	82.4	814	969	7	109	1.0e-11	39.2	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918251275	558	81.41	70	553	78	423	6.2e-59	194.5	COG0840	Methyl-accepting chemotaxis protein	408
2918251276	401	19.16	237	395	353	439	5.2e-19	28.8	COG3259	Coenzyme F420-reducing hydrogenase, alpha subunit	441
2918251276	401	23.57	1	134	11	117	5.2e-19	32.6	COG3259	Coenzyme F420-reducing hydrogenase, alpha subunit	441
2918251277	240	84	21	240	37	225	1.1e-72	238.6	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2918251278	475	85.78	33	426	27	376	1.0e-101	335.3	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
2918251279	405	97.43	33	404	8	386	7.6e-40	131.3	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918251280	263	99.32	1	263	2	291	1.6e-67	222.8	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
2918251281	322	92.77	1	322	5	325	2.1e-113	373.7	COG1171	Threonine dehydratase	347
2918251282	145	80.25	4	141	23	152	8.1e-08	27.6	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918251283	83	60.32	19	82	26	63	1.4e-15	51.4	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918251284	211	80.95	2	208	26	212	6.3e-20	65.5	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
2918251285	297	89.56	14	297	27	292	1.4e-33	110.9	COG2177	Cell division protein FtsX	297
2918251286	226	97.31	1	222	1	217	6.7e-84	275.7	COG2884	ABC-type ATPase involved in cell division	223
2918251287	254	83.52	11	253	22	239	2.7e-41	136	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918251288	208	95.62	4	161	3	155	1.5e-39	130.3	COG0680	Ni,Fe-hydrogenase maturation factor	160
2918251289	106	95.12	1	80	1	78	1.3e-10	35.8	COG0298	Hydrogenase maturation factor	82
2918251292	293	94.55	24	78	2	53	6.1e-19	62	COG1773	Rubredoxin	55
2918251293	113	98.26	1	113	1	113	4.8e-34	111.7	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
2918251294	331	94.95	106	305	8	195	3.3e-61	200.7	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
2918251295	497	98.07	4	496	7	464	0.0e+00	489.9	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918251296	101	92.68	1	87	1	76	1.9e-28	93	COG0298	Hydrogenase maturation factor	82
2918251297	382	95.91	13	378	13	364	0.0e+00	498.6	COG0409	Hydrogenase maturation factor	364
2918251298	365	99.71	23	365	2	339	8.3e-111	364.6	COG0309	Hydrogenase maturation factor	339
2918251299	181	83.08	2	178	10	176	3.2e-44	145.3	COG2370	Hydrogenase/urease accessory protein HupE	201
2918251300	557	99.75	8	468	2	407	0.0e+00	449.2	COG0644	Dehydrogenase (flavoprotein)	396
2918251301	294	97.52	97	289	4	200	1.8e-65	214.6	COG1573	Uracil-DNA glycosylase	202
2918251302	669	98.68	331	629	3	301	4.0e-51	169.5	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2918251303	184	94.71	6	172	6	166	2.3e-61	200.6	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
2918251304	341	42.51	27	277	130	268	1.1e-10	34.6	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2918251306	468	60.32	99	468	146	487	1.5e-12	41.1	COG1404	Serine protease, subtilisin family	508
2918251307	563	66.03	8	297	100	342	2.0e-24	25.7	COG0457	Tetratricopeptide (TPR) repeat	291
2918251307	563	83.7	254	560	49	356	2.0e-24	65.7	COG0457	Tetratricopeptide (TPR) repeat	291
2918251308	140	89.58	2	140	2	130	5.8e-27	89.1	COG2703	Hemerythrin	144
2918251309	257	49.31	21	235	61	238	8.3e-12	39.5	COG3177	Fic family protein	348
2918251310	584	95.93	15	549	21	562	2.0e-98	325.1	COG2936	Predicted acyl esterase	563
2918251311	569	97.95	2	569	9	580	0.0e+00	693.4	COG1001	Adenine deaminase	584
2918251312	469	81.98	2	467	67	389	3.1e-74	243.5	COG0642	Signal transduction histidine kinase	336
2918251313	562	88.24	89	560	49	423	5.1e-61	194.5	COG0840	Methyl-accepting chemotaxis protein	408
2918251315	729	15.52	1	142	6	122	0.0e+00	73.1	COG0643	Chemotaxis protein histidine kinase CheA	716
2918251315	729	51.46	228	729	354	741	0.0e+00	445.5	COG0643	Chemotaxis protein histidine kinase CheA	716
2918251316	142	91.73	7	133	5	126	3.4e-32	105.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918251317	291	98.15	14	287	3	267	4.4e-81	266.8	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918251318	205	6.52	151	192	102	124	4.8e-15	14.5	COG1413	HEAT repeat	335
2918251318	205	33.43	16	154	155	272	4.8e-15	37.6	COG1413	HEAT repeat	335
2918251319	361	98.01	1	359	1	345	1.4e-98	324.8	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918251320	549	83.64	20	181	20	157	8.3e-77	62.4	COG0835	Chemotaxis signal transduction protein	165
2918251320	549	83.64	197	354	16	153	8.3e-77	85.7	COG0835	Chemotaxis signal transduction protein	165
2918251320	549	87.88	372	544	15	159	8.3e-77	99.3	COG0835	Chemotaxis signal transduction protein	165
2918251321	656	64.71	53	357	143	417	2.6e-77	139.6	COG0840	Methyl-accepting chemotaxis protein	408
2918251321	656	66.35	354	656	135	416	2.6e-77	120.7	COG0840	Methyl-accepting chemotaxis protein	408
2918251322	226	66.34	6	209	10	143	4.4e-20	67	COG1776	Chemotaxis protein CheY-P-specific phosphatase CheC	203
2918251323	108	44.55	1	105	19	112	5.2e-17	56.9	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918251324	1224	59.78	552	726	136	355	2.0e-47	33.3	COG0457	Tetratricopeptide (TPR) repeat	291
2918251324	1224	82.07	647	944	57	358	2.0e-47	58	COG0457	Tetratricopeptide (TPR) repeat	291
2918251324	1224	83.42	8	289	60	366	2.0e-47	86.1	COG0457	Tetratricopeptide (TPR) repeat	291
2918251325	265	95.19	3	265	14	270	3.1e-111	365.4	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
2918251326	222	96.85	1	218	8	222	2.3e-92	303.1	COG2011	ABC-type methionine transport system, permease component	222
2918251327	350	99.71	1	344	1	339	0.0e+00	460.4	COG1135	ABC-type methionine transport system, ATPase component	339
2918251328	260	95.93	1	260	12	270	7.4e-93	305.2	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
2918251330	236	74.74	19	236	2	220	4.1e-61	201.6	COG0040	ATP phosphoribosyltransferase	290
2918251331	441	94.87	6	431	19	425	0.0e+00	564.8	COG0141	Histidinol dehydrogenase	425
2918251332	160	98.12	1	160	4	160	2.9e-71	233.5	COG5328	Uncharacterized protein, UPF0262 family	160
2918251333	157	93.24	13	149	3	140	1.8e-28	94.3	COG0394	Protein-tyrosine-phosphatase	139
2918251334	769	60.99	623	759	13	123	1.2e-07	25.5	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918251334	769	89.09	166	610	42	392	1.7e-85	282.7	COG0642	Signal transduction histidine kinase	336
2918251336	72	96	1	72	1	72	4.6e-35	113.8	COG0361	Translation initiation factor IF-1	75
2918251337	198	97.42	3	198	3	191	3.9e-60	197.2	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
2918251338	395	78.32	5	394	12	394	2.2e-81	268.3	COG1530	Ribonuclease G or E	487
2918251339	62	86.15	3	62	4	59	7.9e-19	62	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
2918251340	459	97.43	1	458	1	455	3.2e-87	287.8	COG4267	Uncharacterized membrane protein	467
2918251341	266	98.46	1	259	3	258	3.6e-112	368.9	COG3622	Hydroxypyruvate isomerase	260
2918251342	255	98.88	3	252	2	266	9.9e-66	216.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918251343	497	45.43	267	484	16	189	6.0e-41	43.6	COG0477	MFS family permease	338
2918251343	497	71.02	22	299	8	279	6.0e-41	95.7	COG0477	MFS family permease	338
2918251344	1027	86.8	311	747	49	390	4.5e-51	169.3	COG0642	Signal transduction histidine kinase	336
2918251344	1027	90.23	904	1024	6	125	5.7e-37	62.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918251344	1027	93.98	757	884	6	130	5.7e-37	55.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918251345	593	40.22	176	300	105	252	2.2e-27	37.9	COG0457	Tetratricopeptide (TPR) repeat	291
2918251345	593	65.22	3	208	105	344	2.2e-27	64.6	COG0457	Tetratricopeptide (TPR) repeat	291
2918251346	398	97.42	72	394	3	304	3.8e-69	227.8	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918251347	497	98.2	1	493	9	500	0.0e+00	584.7	COG1129	ABC-type sugar transport system, ATPase component	500
2918251348	347	95.92	28	347	7	312	8.1e-92	302.2	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918251349	326	97.25	2	326	7	324	4.1e-55	181.6	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918251350	351	99.28	7	325	3	278	3.0e-52	172.4	COG1082	Sugar phosphate isomerase/epimerase	274
2918251351	396	96.87	17	394	3	342	2.5e-71	235.5	COG0673	Predicted dehydrogenase	342
2918251352	106	23.96	14	93	13	64	3.6e-05	18.1	COG5637	Uncharacterized membrane protein	217
2918251353	390	97.86	38	386	3	368	2.1e-91	301.6	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918251354	217	98.58	4	213	2	209	1.1e-52	173.4	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918251355	1196	80.2	632	1054	73	388	4.1e-54	179.2	COG0642	Signal transduction histidine kinase	336
2918251355	1196	89.4	1	558	42	488	2.9e-70	230.8	COG0591	Na+/proline symporter	493
2918251361	214	97.24	3	213	5	215	2.5e-37	123.1	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
2918251362	337	98.31	8	335	5	352	3.3e-96	316.6	COG0306	Phosphate/sulfate permease	326
2918251364	884	46.98	596	737	3	111	5.8e-30	33.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918251364	884	47.84	755	883	2	112	5.8e-30	63	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918251364	884	82.74	184	575	65	390	3.2e-73	241.4	COG0642	Signal transduction histidine kinase	336
2918251365	282	97.01	5	282	1	292	5.5e-47	155.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918251366	134	82.61	67	129	5	61	3.2e-23	18.7	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918251366	134	98.55	1	68	1	68	3.2e-23	56	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918251367	158	93.04	1	153	5	151	4.5e-39	128.7	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918251368	372	99.73	1	371	1	369	0.0e+00	540.7	COG0686	Alanine dehydrogenase	371
2918251369	301	99.34	1	300	2	300	2.0e-97	321	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918251370	497	94.43	148	481	14	318	4.7e-96	316.7	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918251371	304	99.21	8	275	3	254	4.2e-99	325.6	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918251372	238	99.16	1	236	2	236	1.1e-100	330.4	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918251374	557	87.29	55	548	53	423	3.3e-54	179.3	COG0840	Methyl-accepting chemotaxis protein	408
2918251375	392	98.5	7	391	3	395	1.6e-108	357.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918251377	227	93.86	1	227	15	228	1.2e-58	193.5	COG4291	Uncharacterized membrane protein	228
2918251378	369	88.61	5	368	20	377	7.3e-53	174.8	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918251379	62	44.83	1	52	1	26	2.8e-03	12.3	COG5567	Predicted small periplasmic lipoprotein YifL (function unknown0	58
2918251380	464	96.47	2	447	4	440	0.0e+00	693.9	COG4303	Ethanolamine ammonia-lyase, large subunit	453
2918251381	268	78.91	1	239	62	293	9.1e-74	243	COG4302	Ethanolamine ammonia-lyase, small subunit	294
2918251382	466	93.9	1	456	7	468	3.5e-68	225	COG0531	Amino acid transporter	466
2918251383	331	73.48	174	331	27	123	1.3e-19	64.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918251385	151	85.81	12	148	5	131	5.7e-06	20.6	COG5612	Uncharacterized membrane protein	148
2918251386	143	21.36	13	133	29	97	9.6e-03	8.7	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918251387	186	95.7	10	185	2	179	3.9e-42	138.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918251388	1029	99.8	2	1014	2	1013	0.0e+00	1091.5	COG0841	Multidrug efflux pump subunit AcrB	1009
2918251389	1044	99.9	2	1020	1	1013	0.0e+00	1158.3	COG0841	Multidrug efflux pump subunit AcrB	1009
2918251390	467	95.38	1	393	14	385	2.2e-64	212.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918251393	211	99.52	1	210	1	207	2.9e-55	181.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918251394	227	98.62	7	226	2	216	6.4e-67	220.3	COG0819	Thiaminase	218
2918251396	190	97.45	2	190	2	192	1.0e-47	157.3	COG0693	Putative intracellular protease/amidase	188
2918251397	117	79.41	1	111	1	81	4.0e-36	117.6	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918251398	171	95.53	1	171	6	176	1.3e-55	182.3	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
2918251399	379	46.15	19	102	42	95	2.3e-05	17.7	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918251399	379	96.25	109	379	8	264	2.5e-84	277.2	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2918251400	271	95.06	13	271	6	255	2.2e-100	329.9	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
2918251401	319	81.35	1	316	1	301	5.4e-48	158.6	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2918251402	215	92.68	2	210	14	203	1.3e-44	146.7	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
2918251404	345	98.86	1	344	1	347	4.8e-72	235.6	COG0673	Predicted dehydrogenase	342
2918251405	190	85.71	12	142	16	129	4.5e-23	76.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918251406	596	12.19	4	113	4	72	2.7e-18	24.4	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918251406	596	13.07	489	596	349	422	2.7e-18	9.9	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918251406	596	16.61	213	375	138	231	2.7e-18	19.4	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918251406	596	26.68	323	493	309	459	2.7e-18	11.7	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918251407	347	31.19	3	86	15	82	5.6e-37	11.8	COG0516	IMP dehydrogenase/GMP reductase	170
2918251407	347	93.12	134	344	5	207	5.6e-37	109.4	COG0516	IMP dehydrogenase/GMP reductase	170
2918251410	658	22.28	466	658	593	762	2.8e-122	117.3	COG0209	Ribonucleotide reductase alpha subunit	696
2918251410	658	58.58	65	470	78	524	2.8e-122	285.1	COG0209	Ribonucleotide reductase alpha subunit	696
2918251411	360	90.94	20	345	27	337	2.1e-62	205.5	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
2918251412	582	56.84	53	386	2	217	1.3e-45	150.2	COG4249	Uncharacterized protein, contains caspase domain	380
2918251413	614	99.5	3	612	4	598	0.0e+00	649.9	COG0322	Excinuclease UvrABC, nuclease subunit	581
2918251414	361	53.78	141	334	27	161	7.9e-22	71.4	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918251418	116	91.89	1	80	3	70	1.9e-16	54.5	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
2918251419	196	96.53	1	195	4	198	1.2e-50	166.4	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
2918251420	885	38.36	658	885	369	597	6.3e-101	220.6	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
2918251420	885	43.38	358	671	34	292	6.3e-101	111.3	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
2918251421	532	94.58	1	528	1	506	9.9e-122	402.1	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918251422	223	81.82	2	220	12	182	4.8e-21	71.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918251425	160	83.89	6	160	19	143	3.4e-44	144.8	COG3019	Uncharacterized conserved protein	149
2918251426	386	86.26	1	374	5	343	2.5e-106	350.9	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2918251427	311	95.35	2	297	2	288	1.7e-47	157.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918251428	331	98.12	9	330	6	318	1.4e-92	304.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918251429	291	94.06	10	271	2	270	1.4e-27	91.2	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918251430	397	91.15	1	371	30	369	1.1e-94	312	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918251431	223	95.75	3	215	7	209	2.7e-57	188.4	COG0684	Regulator of RNase E activity RraA	210
2918251432	329	97.81	6	328	7	318	1.2e-82	272.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918251433	259	87.26	43	258	21	205	2.1e-45	149.4	COG0684	Regulator of RNase E activity RraA	210
2918251434	306	74.83	10	280	2	215	1.4e-26	87.7	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918251436	497	98.41	1	497	3	498	0.0e+00	662.9	COG3333	TctA family transporter	504
2918251438	249	96.91	4	249	5	255	1.9e-19	64.6	COG0730	Uncharacterized membrane protein YfcA	258
2918251439	838	97.99	126	838	17	795	1.5e-70	233.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918251442	545	95.26	16	481	6	427	5.1e-41	132.8	COG3182	Uncharacterized iron-regulated membrane protein	442
2918251443	97	33.33	3	86	54	112	5.0e-04	14	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918251444	416	94.26	9	409	21	414	7.8e-48	157.3	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918251445	417	96.41	10	417	14	416	6.2e-74	244.2	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918251446	699	99.6	43	636	1	496	0.0e+00	503.8	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
2918251447	110	88.89	25	105	5	76	2.8e-08	28.3	COG0236	Acyl carrier protein	80
2918251448	386	95.49	4	383	15	395	4.7e-50	165.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918251449	317	44.32	65	317	228	418	4.6e-21	69.6	COG0172	Seryl-tRNA synthetase	429
2918251451	844	89.03	70	834	78	824	2.6e-74	245.4	COG3250	Beta-galactosidase/beta-glucuronidase	808
2918251452	593	36.29	18	127	47	132	1.4e-12	13.3	COG0412	Dienelactone hydrolase	236
2918251452	593	40.51	331	430	47	142	1.4e-12	26.7	COG0412	Dienelactone hydrolase	236
2918251453	373	94.78	1	362	6	350	5.5e-63	208.1	COG5330	Uncharacterized conserved protein, DUF2336 family	364
2918251454	216	98.58	1	214	1	208	3.2e-49	162.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918251455	342	67.34	154	342	64	197	2.3e-32	107.3	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918251456	346	86.54	18	328	18	242	2.9e-38	126	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918251459	366	95.9	12	366	3	353	1.3e-88	292.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918251461	238	99.16	1	236	2	236	1.0e-100	330.5	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918251462	300	99.61	7	274	2	254	4.2e-98	322.3	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918251463	495	95.05	149	481	12	318	1.1e-95	315.4	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918251464	301	99.34	1	300	2	300	2.0e-97	321	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918251466	306	95.16	1	302	7	301	3.9e-76	250.8	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918251468	553	87.2	4	521	10	486	3.3e-64	212.3	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
2918251469	104	84.96	1	102	11	106	7.5e-32	104.2	COG3952	Uncharacterized N-terminal domain of lipid-A-disaccharide synthase	113
2918251470	253	52.37	10	247	4	191	4.6e-23	77.6	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918251471	531	25.75	429	531	265	358	6.5e-123	34.9	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918251471	531	94.52	12	413	18	362	6.5e-123	374.2	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918251472	298	49.57	14	181	18	75	4.4e-05	16.5	COG2963	Transposase and inactivated derivatives	116
2918251473	629	68.53	263	623	123	392	8.5e-44	144.4	COG0642	Signal transduction histidine kinase	336
2918251474	141	86.96	1	141	13	152	4.7e-48	157.8	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
2918251475	489	98.24	25	466	2	391	5.2e-101	332.9	COG0348	Polyferredoxin	386
2918251478	387	85.48	7	385	49	360	7.3e-88	289.5	COG1858	Cytochrome c peroxidase	364
2918251479	281	93.6	16	280	2	235	3.1e-23	76.9	COG1587	Uroporphyrinogen-III synthase	248
2918251480	208	68.2	1	188	13	175	9.7e-28	91.6	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918251482	133	87.12	8	133	3	117	7.0e-24	79.4	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918251483	541	97.54	2	540	5	558	3.2e-118	390.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918251484	378	89.39	4	378	3	398	2.5e-55	177.1	COG3182	Uncharacterized iron-regulated membrane protein	442
2918251488	312	96.72	2	309	9	303	6.4e-65	213.9	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
2918251489	255	93.31	7	250	5	241	4.1e-64	211.1	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
2918251490	296	94.57	17	292	9	269	3.6e-68	224.3	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2918251491	294	47.54	75	294	137	281	1.4e-17	58.2	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
2918251492	337	92.81	4	331	15	311	8.2e-59	193.6	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918251493	141	72.67	10	138	21	145	1.5e-14	48.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918251494	204	91.87	3	203	11	202	1.5e-26	89	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918251495	1140	81.61	421	647	38	250	1.5e-31	103.8	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918251495	1140	95.77	626	1138	10	553	7.4e-83	273	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918251496	220	90.21	31	220	5	179	1.5e-19	65.6	COG0558	Phosphatidylglycerophosphate synthase	192
2918251497	218	62.45	5	217	65	227	2.3e-23	77.4	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918251498	317	96.7	10	317	10	302	2.3e-115	380.1	COG4589	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase	303
2918251499	500	79.03	6	495	117	557	0.0e+00	443.5	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
2918251500	303	89.36	1	298	1	294	1.8e-89	294.8	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918251501	312	98.99	5	307	3	297	5.4e-102	335.7	COG3246	Uncharacterized conserved protein, DUF849 family	298
2918251502	259	98.51	1	257	4	267	5.8e-75	246.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918251503	403	94.81	9	381	9	355	5.5e-43	141.9	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918251506	569	99.64	2	563	3	560	0.0e+00	831.3	COG2060	K+-transporting ATPase, A chain	560
2918251507	716	99.12	15	716	6	681	0.0e+00	1092.5	COG2216	High-affinity K+ transport system, ATPase chain B	681
2918251508	202	99.47	1	198	1	188	8.0e-74	242.2	COG2156	K+-transporting ATPase, c chain	190
2918251509	933	98.44	20	920	5	887	0.0e+00	1115.3	COG2205	K+-sensing histidine kinase KdpD	890
2918251510	227	98.71	3	227	2	230	3.3e-77	253.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918251511	429	98.33	11	429	6	416	2.2e-98	324.5	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918251512	279	94.32	13	274	5	253	2.1e-32	106.8	COG3971	2-keto-4-pentenoate hydratase	264
2918251513	776	97.11	13	776	24	795	7.7e-101	333.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918251514	188	90.34	6	185	15	173	2.1e-55	181.6	COG3721	Putative heme iron utilization protein	176
2918251515	499	79.7	11	494	76	389	2.1e-48	159	COG0642	Signal transduction histidine kinase	336
2918251516	222	97.84	1	222	2	228	2.3e-72	237.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918251517	267	93.44	1	254	1	242	1.2e-67	222.1	COG4559	ABC-type hemin transport system, ATPase component	259
2918251518	361	98.21	13	359	5	333	4.1e-84	276.9	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918251519	285	88.33	1	283	28	292	4.5e-72	236.8	COG4558	ABC-type hemin transport system, periplasmic component	300
2918251520	317	87.97	5	317	42	348	5.9e-82	269.8	COG3720	Putative heme degradation protein	349
2918251521	643	96.9	5	230	4	222	2.4e-85	279.5	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918251521	643	99.8	268	643	2	510	5.9e-64	211.5	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918251522	402	95.13	2	402	13	383	1.0e-50	167.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918251523	168	90.86	1	168	10	178	3.2e-39	129.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918251524	319	97.52	1	319	7	321	1.6e-81	268.3	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918251525	836	93.75	105	836	43	717	0.0e+00	745.5	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
2918251526	301	94.03	2	300	9	307	3.1e-43	142.5	COG0462	Phosphoribosylpyrophosphate synthetase	314
2918251528	951	66.52	471	950	216	656	1.1e-120	398.5	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918251528	951	96.02	32	382	12	349	1.7e-25	78.8	COG3614	Extracellular (periplasmic) sensor domain CHASE1 (specificity unknown)	348
2918251529	291	98.2	1	267	5	277	4.2e-24	79.9	COG1082	Sugar phosphate isomerase/epimerase	274
2918251531	587	12.37	499	587	347	416	1.9e-32	14.4	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918251531	587	16.43	359	514	368	460	1.9e-32	11.3	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918251531	587	39.4	24	387	8	230	1.9e-32	82.8	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918251532	303	97.56	31	280	3	242	5.9e-62	203.1	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918251533	425	93.99	12	400	10	353	2.9e-46	152.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918251534	289	99	1	287	2	299	5.7e-75	247	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918251535	852	96.9	8	311	10	322	2.4e-69	228.1	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918251535	852	99.16	342	586	2	236	0.0e+00	167.4	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918251535	852	99.58	608	836	2	237	0.0e+00	260.4	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918251536	265	90.85	4	263	2	259	2.2e-52	172.3	COG0169	Shikimate 5-dehydrogenase	283
2918251537	583	17.14	10	124	8	104	1.3e-28	49.1	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918251537	583	24.03	201	379	138	273	1.3e-28	24.1	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918251537	583	27.74	374	571	367	523	1.3e-28	16.9	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918251538	262	97.39	1	251	7	267	9.2e-60	196.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918251539	137	95.49	3	137	6	132	1.9e-32	106.7	COG3766	Uncharacterized membrane protein YjfL, UPF0719 family	133
2918251540	201	65.2	1	201	20	152	4.3e-22	71.9	COG5463	Uncharacterized conserved protein YgiB, involved in bioifilm formation, UPF0441/DUF1190 family	198
2918251541	400	99.5	1	400	1	395	8.6e-107	351.8	COG0754	Glutathionylspermidine synthase	387
2918251542	560	99.63	35	552	2	535	0.0e+00	592.1	COG4147	Na+(or H+)/acetate symporter ActP	529
2918251543	103	97.06	1	103	1	99	7.4e-29	94.3	COG3162	Uncharacterized membrane protein, DUF485 family	102
2918251544	957	13.29	736	816	388	448	2.5e-41	6.8	COG4564	Signal transduction histidine kinase	459
2918251544	957	26.58	216	365	74	195	2.5e-41	39.7	COG4564	Signal transduction histidine kinase	459
2918251544	957	34.42	53	231	44	201	2.5e-41	89.3	COG4564	Signal transduction histidine kinase	459
2918251545	240	98.71	5	236	1	229	7.5e-68	222.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918251548	1403	29.19	133	193	19	65	2.2e-03	3.9	COG3521	Predicted component of the type VI protein secretion system	159
2918251548	1403	30.43	24	104	24	72	2.2e-03	5.6	COG3521	Predicted component of the type VI protein secretion system	159
2918251549	389	71.2	106	384	102	363	3.8e-50	165	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2918251550	112	80.34	2	112	21	114	1.5e-23	77.3	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918251551	165	85.62	9	163	10	134	1.4e-14	43	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2918251552	945	28.43	269	419	60	171	7.6e-51	5.6	COG0642	Signal transduction histidine kinase	336
2918251552	945	64.84	802	942	11	128	2.0e-15	48.5	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918251552	945	72.59	420	792	106	391	7.6e-51	167.4	COG0642	Signal transduction histidine kinase	336
2918251553	226	98.58	1	222	2	209	8.5e-49	160.5	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918251554	332	53.18	5	284	143	368	5.0e-25	82.8	COG0840	Methyl-accepting chemotaxis protein	408
2918251555	377	99.15	13	374	2	350	1.1e-126	417.2	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918251556	297	98.89	29	292	1	267	6.1e-80	262.7	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918251557	789	69.89	21	111	12	76	1.9e-01	7.1	COG4317	Xanthosine utilization system component, XapX domain	93
2918251557	789	80.47	216	716	84	425	7.7e-102	334.1	COG0840	Methyl-accepting chemotaxis protein	408
2918251558	175	90.91	15	175	11	160	4.6e-40	131.3	COG0835	Chemotaxis signal transduction protein	165
2918251559	738	98.67	3	724	3	746	0.0e+00	642.3	COG0643	Chemotaxis protein histidine kinase CheA	716
2918251560	121	90.23	1	121	6	125	2.1e-33	109.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918251561	84	49.57	16	83	40	97	3.0e-05	18.2	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918251564	1078	67.51	523	929	127	392	7.4e-57	188.4	COG0642	Signal transduction histidine kinase	336
2918251565	574	95.18	1	444	7	440	3.5e-72	237.6	COG2233	Xanthine/uracil permease	451
2918251566	232	98.15	14	232	3	214	3.5e-39	129	COG3806	Anti-sigma factor ChrR, cupin superfamily	216
2918251567	135	92.09	1	132	10	137	7.4e-27	88.6	COG0824	Acyl-CoA thioesterase FadM	137
2918251570	196	75.6	2	194	14	171	1.6e-24	82.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918251571	338	97.81	1	315	1	313	4.1e-92	302.9	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918251572	433	98.82	6	425	5	421	0.0e+00	564.6	COG2379	Glycerate-2-kinase	422
2918251573	294	100	1	284	1	286	6.8e-114	374.4	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918251574	259	99.23	1	259	1	258	5.9e-119	391	COG3622	Hydroxypyruvate isomerase	260
2918251576	692	99.45	5	360	2	362	1.3e-111	367.4	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918251578	71	91.3	1	66	2	64	4.3e-25	81.7	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2918251579	141	89.87	1	141	6	147	4.9e-28	92.8	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918251580	295	68.97	1	295	134	433	3.0e-82	271.1	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918251581	289	91.42	4	289	3	279	1.3e-120	396.4	COG0408	Coproporphyrinogen III oxidase	303
2918251582	161	96.1	1	149	2	149	3.6e-48	157.8	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
2918251583	188	91.67	12	188	5	169	2.6e-51	168.5	COG0723	Rieske Fe-S protein	177
2918251584	422	98.77	7	398	5	404	0.0e+00	500.8	COG1290	Cytochrome b subunit of the bc complex	381
2918251585	253	88.45	3	253	33	277	2.2e-76	251.6	COG2857	Cytochrome c1	250
2918251586	183	95.05	1	183	8	180	1.5e-68	224.9	COG3803	Uncharacterized conserved protein, DUF924 family	182
2918251587	168	90.98	41	167	7	127	4.2e-35	114.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918251588	131	94.35	5	129	5	121	2.5e-29	96.5	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
2918251589	127	76.27	7	108	13	102	3.3e-17	57.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918251591	145	97.86	6	145	3	139	1.4e-51	168.8	COG2510	Uncharacterized membrane protein	140
2918251592	301	87.81	11	298	39	319	1.3e-102	337.2	COG4607	ABC-type enterochelin transport system, periplasmic component	320
2918251593	322	94.7	5	322	16	319	0.0e+00	432.4	COG4606	ABC-type enterochelin transport system, permease component	321
2918251594	330	97.47	14	330	8	315	1.8e-124	409.5	COG4605	ABC-type enterochelin transport system, permease component	316
2918251595	252	99.6	1	252	1	251	1.8e-116	382.6	COG4604	ABC-type enterochelin transport system, ATPase component	252
2918251597	300	88.46	4	274	2	254	2.2e-25	83.7	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918251598	242	97.05	6	236	4	233	1.7e-83	273.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918251599	251	98.82	1	247	4	254	1.8e-84	277.5	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918251600	346	96.59	31	338	8	319	2.7e-72	238	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918251601	288	97.67	1	288	3	296	1.3e-69	229.6	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918251602	395	96.17	10	387	4	355	4.9e-51	168.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918251603	233	95.28	5	218	8	209	8.5e-65	212.8	COG0684	Regulator of RNase E activity RraA	210
2918251604	249	92.68	1	243	7	234	5.2e-42	138.7	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
2918251605	221	96.17	2	216	7	207	1.7e-29	98.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918251606	360	99.21	2	360	2	376	3.7e-129	425.5	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
2918251607	1044	99.8	1	1028	1	1012	0.0e+00	1185.3	COG0841	Multidrug efflux pump subunit AcrB	1009
2918251608	402	95.9	4	384	12	385	6.5e-60	197.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918251609	218	90.43	1	207	5	193	1.6e-30	101.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918251610	426	95.75	1	422	10	415	1.7e-91	301.3	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918251611	304	98.03	3	303	6	303	2.8e-89	293.4	COG1079	ABC-type uncharacterized transport system, permease component	304
2918251612	349	94.13	2	349	13	349	9.5e-105	344.5	COG4603	ABC-type uncharacterized transport system, permease component	356
2918251613	522	99.8	13	510	2	501	0.0e+00	592.6	COG3845	ABC-type uncharacterized transport system, ATPase component	501
2918251614	342	96.88	7	340	5	346	2.5e-62	205.2	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
2918251615	282	97.21	6	282	5	283	2.0e-85	281.1	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2918251616	521	98.16	2	462	5	483	1.2e-93	309.5	COG3119	Arylsulfatase A or related enzyme	475
2918251617	283	94.19	27	283	14	256	2.4e-76	251	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918251618	267	96.14	1	258	4	252	5.0e-103	338.5	COG4525	ABC-type taurine transport system, ATPase component	259
2918251619	334	95.51	1	334	12	330	2.2e-108	356.9	COG4521	ABC-type taurine transport system, periplasmic component	334
2918251621	264	72.76	22	248	62	256	2.9e-44	145.8	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918251622	934	5.77	524	632	108	135	1.2e-14	1.1	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918251622	934	40	656	907	253	446	1.2e-14	44.8	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918251626	487	60	8	133	2	79	2.3e-15	50.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918251626	487	99.1	145	477	3	331	0.0e+00	453.7	COG3800	Predicted transcriptional regulator	332
2918251627	510	97.91	1	510	12	526	0.0e+00	748.7	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2918251628	666	99.85	1	666	1	645	0.0e+00	903.9	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918251629	202	91.35	25	201	12	180	1.8e-44	145.8	COG1268	Biotin transporter BioY	184
2918251630	717	96.69	566	716	2	147	7.6e-59	192.4	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
2918251630	717	97.45	10	551	13	546	0.0e+00	829.8	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
2918251631	62	46.25	11	62	44	80	6.8e-09	30.5	COG5302	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid	80
2918251633	230	93.89	4	229	2	216	2.9e-68	224	COG5482	Uncharacterized protein	229
2918251634	397	63.71	94	397	138	388	1.1e-51	171	COG0642	Signal transduction histidine kinase	336
2918251635	207	95.61	1	207	7	202	2.0e-58	191.6	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
2918251636	476	96.27	2	443	2	440	0.0e+00	534	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
2918251637	338	98.26	4	338	5	343	3.4e-111	366.4	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
2918251639	567	93.98	1	514	5	129	1.0e-29	97.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918251640	379	72.34	10	377	104	388	1.7e-64	213.2	COG0642	Signal transduction histidine kinase	336
2918251641	405	97.47	13	404	11	396	2.9e-103	340.7	COG3213	Uncharacterized protein involved in response to NO	396
2918251642	123	93.98	4	123	4	128	1.1e-10	36	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918251645	44	2.91	1	33	998	1027	2.5e-04	13.4	COG3696	Cu/Ag efflux pump CusA	1027
2918251646	393	99.75	2	393	2	394	0.0e+00	454.1	COG0183	Acetyl-CoA acetyltransferase	392
2918251647	264	98.49	2	261	5	265	1.8e-68	225.3	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918251648	243	89.47	17	220	3	189	3.3e-31	103	COG0406	Broad specificity phosphatase PhoE	208
2918251650	350	92.35	7	328	10	311	3.0e-38	126.1	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2918251651	398	98.75	1	393	1	394	4.3e-95	313.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918251652	255	98.88	5	252	2	266	2.5e-76	251.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918251653	256	88.04	50	241	17	200	4.0e-18	61.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918251654	1165	78.64	683	1154	37	419	1.3e-16	51	COG1061	Superfamily II DNA or RNA helicase	442
2918251655	413	96.46	20	413	11	392	0.0e+00	437.1	COG2807	Cyanate permease	395
2918251656	608	64.56	125	600	218	645	3.1e-121	399.8	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918251657	341	98.19	1	338	4	329	8.6e-110	361.6	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918251658	425	99.74	47	425	1	378	0.0e+00	451.9	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918251659	175	92.09	1	173	5	167	1.5e-43	142.8	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918251660	185	95.65	10	169	1	154	3.7e-59	193.3	COG3265	Gluconate kinase	161
2918251661	362	98.8	35	362	1	330	6.8e-95	312.6	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918251662	281	36.29	97	264	69	154	3.7e-06	20.6	COG0412	Dienelactone hydrolase	236
2918251663	554	82.57	13	554	104	591	3.7e-40	132.5	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
2918251664	748	92.27	289	735	30	375	6.3e-45	145.6	COG4585	Signal transduction histidine kinase	365
2918251665	255	97.63	17	255	4	209	1.3e-41	137	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918251666	411	93.55	4	399	22	398	2.6e-128	422.4	COG3135	Predicted benzoate:H+ symporter BenE	402
2918251667	43	18.47	1	34	123	151	2.9e-04	15.4	COG4754	Uncharacterized protein	157
2918251668	434	96.13	34	421	5	377	2.5e-73	241.8	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918251669	399	97.46	8	396	7	389	0.0e+00	444.3	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2918251671	249	98.73	16	249	3	236	9.1e-94	307.5	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918251672	255	99.21	1	250	2	253	4.6e-98	322	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918251673	355	95.67	25	332	8	316	8.2e-83	272.5	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918251674	305	98.01	4	305	4	298	1.4e-77	255.5	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918251675	374	95.36	14	373	4	352	1.1e-69	229.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918251676	165	56.16	8	159	87	209	1.4e-03	12.5	COG2345	Predicted transcriptional regulator, ArsR family	218
2918251677	383	97.02	43	352	9	301	3.4e-67	220.9	COG0031	Cysteine synthase	300
2918251678	126	96.32	1	126	3	133	5.5e-34	111.6	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918251679	156	96.84	1	152	5	157	1.4e-41	136.6	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918251680	586	28.08	1	78	106	178	2.0e-30	40.9	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918251680	586	29.23	211	292	112	187	2.0e-30	32.2	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918251680	586	37.31	109	216	85	181	2.0e-30	33	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918251682	624	83.01	8	620	104	621	8.1e-104	338.4	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918251683	596	65.22	2	259	106	345	8.9e-19	62.3	COG0457	Tetratricopeptide (TPR) repeat	291
2918251684	499	24.62	4	78	109	172	6.3e-19	27.3	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918251684	499	34.62	89	198	99	188	6.3e-19	38.6	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918251685	920	89.1	355	908	67	622	0.0e+00	465	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918251686	634	67.66	3	369	60	308	4.6e-16	49.7	COG0457	Tetratricopeptide (TPR) repeat	291
2918251687	590	36.14	5	140	194	326	1.9e-21	23.1	COG0457	Tetratricopeptide (TPR) repeat	291
2918251687	590	61.14	108	366	75	299	1.9e-21	48.1	COG0457	Tetratricopeptide (TPR) repeat	291
2918251688	903	73.91	332	674	71	342	2.9e-19	58.5	COG0457	Tetratricopeptide (TPR) repeat	291
2918251690	1217	16.54	874	932	118	160	1.1e-16	12.6	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918251690	1217	25.77	683	772	103	169	1.1e-16	13.2	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918251690	1217	42.31	761	887	117	226	1.1e-16	43.3	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918251690	1217	49.39	8	308	204	405	1.6e-09	31.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918251691	382	66.75	13	380	126	398	2.8e-16	54.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918251692	270	97.14	13	257	2	239	6.2e-92	301.7	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
2918251693	343	91.67	92	343	13	221	6.7e-46	150.7	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918251694	637	99.04	4	633	2	622	0.0e+00	846	COG1154	Deoxyxylulose-5-phosphate synthase	627
2918251695	300	79.57	7	298	3	263	8.4e-80	262.5	COG0142	Geranylgeranyl pyrophosphate synthase	322
2918251696	90	76.54	9	87	8	69	7.6e-23	74.6	COG1722	Exonuclease VII small subunit	81
2918251697	309	89.63	1	308	4	314	2.1e-100	330.5	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2918251698	75	91.25	1	75	6	78	1.1e-21	71.2	COG0425	TusA-related sulfurtransferase	78
2918251699	309	96.57	1	307	3	312	7.5e-78	256.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918251701	441	95.83	11	438	9	445	4.4e-110	362.5	COG2233	Xanthine/uracil permease	451
2918251702	291	98.99	1	291	1	293	5.8e-119	391.2	COG2321	Predicted metalloprotease	295
2918251703	369	92.27	1	369	6	375	3.4e-106	350	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918251704	256	99.63	1	254	1	267	8.6e-62	203.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918251705	494	99.16	8	487	2	476	0.0e+00	561.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918251707	408	97.54	7	387	7	363	1.4e-44	147	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918251708	253	95.53	4	246	4	238	3.1e-47	154.9	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918251709	389	96.7	2	388	13	393	0.0e+00	576.3	COG0027	Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	394
2918251710	460	97.82	21	447	10	412	1.0e-127	421	COG4222	Uncharacterized conserved protein	391
2918251711	1042	99.9	7	1016	1	1013	0.0e+00	928.8	COG0841	Multidrug efflux pump subunit AcrB	1009
2918251712	382	95.38	1	376	12	383	4.5e-49	162	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918251713	220	75.12	13	219	13	169	5.9e-23	77	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918251714	358	93.27	44	346	13	289	9.8e-91	298.3	COG1533	DNA repair photolyase	297
2918251715	208	94.67	17	182	5	164	1.3e-51	169.1	COG1247	L-amino acid N-acyltransferase YncA	169
2918251716	778	98.82	133	777	7	592	0.0e+00	657.3	COG1982	Arginine/lysine/ornithine decarboxylase	557
2918251717	306	78.79	173	305	22	125	1.4e-22	74	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918251718	390	99.49	1	387	2	392	4.7e-73	241.4	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918251719	515	91.2	5	509	42	559	6.3e-116	382.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918251720	340	99.4	11	340	2	330	7.5e-90	296.1	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918251721	303	99.3	2	293	2	285	3.1e-98	323	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918251722	402	96.45	9	378	9	361	4.2e-41	135.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918251723	499	98.96	21	499	3	476	0.0e+00	516.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918251724	251	95.09	1	251	10	261	4.5e-54	178.1	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918251725	212	84.91	1	205	23	219	9.0e-53	173.5	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918251728	519	74.02	138	493	132	507	1.2e-113	369.6	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2918251730	638	99.84	1	636	1	636	0.0e+00	567.9	COG4548	Nitric oxide reductase activation protein	637
2918251731	269	72.42	3	267	19	257	1.3e-51	170.1	COG0714	MoxR-like ATPase	329
2918251732	449	64.44	1	438	245	706	0.0e+00	499.4	COG3256	Nitric oxide reductase large subunit	717
2918251733	150	51.83	5	148	55	139	1.5e-08	29.4	COG2010	Cytochrome c, mono- and diheme variants	150
2918251734	188	84.04	6	188	32	210	1.5e-44	146.2	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918251737	304	98.34	1	284	1	296	1.1e-44	147.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918251739	153	49.17	7	143	122	240	7.3e-16	53	COG2202	PAS domain	232
2918251740	354	19.42	225	331	388	481	4.1e-25	13.9	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2918251740	354	47.31	3	259	4	232	4.1e-25	71.7	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2918251742	388	96.3	29	216	6	187	4.0e-74	242.4	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
2918251742	388	97.62	215	377	4	167	2.6e-50	165.3	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2918251743	248	98.73	11	248	4	236	1.3e-120	395.3	COG3826	Uncharacterized protein	236
2918251746	67	34.29	1	62	31	66	1.3e-03	13.6	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
2918251747	480	73.85	316	479	2	162	1.5e-27	90.6	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918251747	480	79.82	6	316	49	321	1.2e-51	170.2	COG0668	Small-conductance mechanosensitive channel	316
2918251750	543	58.82	27	273	28	177	5.2e-08	26.8	COG1462	Curli biogenesis system outer membrane secretion channel CsgG	252
2918251751	257	91.96	53	257	13	195	5.0e-31	102.8	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918251754	632	33.25	235	380	263	397	3.2e-26	38.8	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2918251754	632	39.16	12	209	12	170	3.2e-26	51.3	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2918251754	632	75.82	360	622	51	235	1.2e-48	158.8	COG2114	Adenylate cyclase, class 3	227
2918251755	868	83.78	548	868	54	332	3.7e-66	218	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918251758	236	98.17	8	226	4	217	1.9e-44	146.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918251762	294	97.63	7	294	5	292	3.0e-41	136.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918251763	192	95.79	1	191	6	187	3.5e-52	171.1	COG1971	Putative Mn2+ efflux pump MntP	190
2918251765	439	97.88	2	437	3	417	3.0e-116	382.9	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918251766	399	99.02	1	399	1	404	0.0e+00	548.6	COG3748	Uncharacterized membrane protein	407
2918251767	204	93.78	7	203	7	202	5.1e-23	77.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918251768	533	96.13	9	531	11	556	2.5e-120	396.8	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918251769	607	97.24	21	469	8	395	1.0e-93	309.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918251770	174	73.04	14	114	31	114	1.4e-08	29.1	COG5442	Flagellar biosynthesis regulator FlaF	115
2918251771	342	98.53	1	318	2	336	1.1e-46	148.7	COG0859	ADP-heptose:LPS heptosyltransferase	334
2918251772	384	99.45	1	362	1	363	6.5e-49	161.5	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
2918251773	729	20.67	22	204	51	179	7.0e-96	17.2	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918251773	729	86.7	136	722	74	614	7.0e-96	298.3	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918251775	257	29.53	11	222	3	108	3.4e-12	41.7	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918251779	393	98.49	1	389	6	397	1.9e-31	103.6	COG1459	Type II secretory pathway, component PulF	397
2918251782	438	99.06	2	438	4	426	0.0e+00	666.1	COG3508	Homogentisate 1,2-dioxygenase	427
2918251783	133	90.65	13	131	8	104	1.7e-15	51.3	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2918251784	375	95.87	10	374	12	359	0.0e+00	501.7	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
2918251785	200	93.79	31	200	4	169	3.4e-58	190.4	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2918251787	133	31.71	2	131	278	407	1.8e-22	74.4	COG3464	Transposase	402
2918251788	2316	13.06	1750	2160	1013	1167	0.0e+00	8.7	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2918251788	2316	26.87	1323	1678	837	1155	0.0e+00	44.3	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2918251788	2316	56.44	664	1340	3	672	0.0e+00	762.8	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2918251788	2316	64.86	586	656	17	64	3.1e-04	11.5	COG3433	Aryl carrier domain	74
2918251788	2316	80.25	2205	2279	14	78	5.0e-05	16.3	COG0236	Acyl carrier protein	80
2918251788	2316	92.78	23	558	34	560	1.7e-62	205.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918251789	4121	21.15	572	1315	848	1098	0.0e+00	26.5	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2918251789	4121	43.13	46	578	6	517	0.0e+00	785.4	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2918251789	4121	64.2	1405	1477	26	77	1.8e-14	19.7	COG0236	Acyl carrier protein	80
2918251789	4121	76.54	2508	2581	15	76	1.8e-14	10.1	COG0236	Acyl carrier protein	80
2918251789	4121	83.95	4012	4081	7	74	1.8e-14	14.3	COG0236	Acyl carrier protein	80
2918251789	4121	97.98	2602	4003	6	1168	0.0e+00	1065.3	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2918251789	4121	99.23	1723	2401	6	648	0.0e+00	433.6	COG1020	Non-ribosomal peptide synthetase component F	642
2918251790	1616	5.98	1118	1380	899	969	0.0e+00	3.4	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2918251790	1616	27.55	651	1145	843	1169	0.0e+00	45.5	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2918251790	1616	55.69	6	668	4	664	0.0e+00	672.7	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2918251790	1616	64.2	1543	1599	28	79	1.6e-04	15.6	COG0236	Acyl carrier protein	80
2918251791	3327	98.15	2452	3116	12	647	0.0e+00	438.8	COG1020	Non-ribosomal peptide synthetase component F	642
2918251791	3327	98.61	1363	2029	8	646	0.0e+00	472.7	COG1020	Non-ribosomal peptide synthetase component F	642
2918251791	3327	99.85	290	959	1	647	0.0e+00	463.7	COG1020	Non-ribosomal peptide synthetase component F	642
2918251792	2898	64.2	2533	2596	25	76	9.3e-13	21.1	COG0236	Acyl carrier protein	80
2918251792	2898	71.6	1455	1527	23	80	9.3e-13	19.3	COG0236	Acyl carrier protein	80
2918251792	2898	96.5	2628	2891	1	248	3.6e-40	133	COG3319	Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase	257
2918251792	2898	98.15	7	1452	4	1168	0.0e+00	1000.5	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2918251792	2898	99.07	1779	2435	7	648	4.3e-127	420.1	COG1020	Non-ribosomal peptide synthetase component F	642
2918251793	602	98.65	14	594	7	590	0.0e+00	498.9	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918251797	300	65.47	9	296	140	412	3.0e-45	149.5	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2918251798	347	96.67	23	346	3	321	3.1e-97	320.1	COG0714	MoxR-like ATPase	329
2918251799	188	72.82	9	187	46	195	1.2e-55	182.6	COG3816	Uncharacterized protein	205
2918251800	253	76.16	53	206	14	144	2.5e-20	67.3	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918251801	429	98.07	10	422	5	411	3.3e-81	267.1	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
2918251802	540	99.25	1	534	3	533	0.0e+00	610.5	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918251803	291	93.02	24	289	8	287	6.8e-21	68.1	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918251804	436	86.89	58	404	32	349	1.0e-32	107.1	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918251806	544	95.05	1	543	10	528	0.0e+00	434.3	COG4615	ABC-type siderophore export system, fused ATPase and permease components	546
2918251807	207	91.37	36	176	3	129	2.4e-19	63.5	COG3597	Uncharacterized conserved protein, DUF697 family	139
2918251809	303	98.01	5	301	2	296	5.3e-66	217.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918251810	211	97.64	2	211	2	208	1.5e-59	195.6	COG3531	Predicted protein-disulfide isomerase , contains CxxC motif	212
2918251811	203	100	1	203	1	211	1.4e-77	254.8	COG2910	Putative NADH-flavin reductase	211
2918251812	253	36.94	41	233	153	285	5.3e-05	14.3	COG3203	Outer membrane protein (porin)	354
2918251813	382	97.15	2	379	2	376	2.1e-117	386.7	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
2918251814	290	15.89	4	102	372	460	1.4e-16	36.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918251814	290	21.96	98	283	362	484	1.4e-16	20.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918251815	565	97.86	7	565	7	555	0.0e+00	982.9	COG2987	Urocanate hydratase	561
2918251816	249	97.07	1	241	7	238	6.8e-62	203.5	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918251817	422	95.82	15	421	12	401	7.1e-129	424.5	COG1228	Imidazolonepropionase or related amidohydrolase	406
2918251818	458	96.23	1	450	11	418	5.7e-80	263.3	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918251819	514	99.2	4	504	3	496	0.0e+00	669	COG2986	Histidine ammonia-lyase	498
2918251820	293	94.85	2	292	7	264	6.6e-96	314.9	COG3741	N-formylglutamate amidohydrolase	272
2918251821	191	97.33	5	185	5	186	2.4e-17	58	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918251822	892	99.01	5	855	2	798	0.0e+00	1055.7	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918251823	304	98.34	1	299	1	296	2.8e-58	192.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918251824	252	94.62	30	252	8	218	2.7e-68	224.3	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
2918251825	332	99.36	1	311	1	312	1.9e-118	389.8	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
2918251826	391	94.62	152	386	6	216	4.2e-73	239.2	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
2918251827	313	96	5	309	13	300	4.6e-89	292.8	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
2918251829	239	93.95	4	239	4	236	2.2e-32	106.7	COG2129	Predicted phosphoesterase, related to the Icc protein	226
2918251830	273	94.39	4	271	5	273	2.8e-65	215.3	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2918251831	545	97.18	8	544	7	558	0.0e+00	501.4	COG2303	Choline dehydrogenase or related flavoprotein	542
2918251832	94	76.92	1	93	1	90	8.2e-15	49.7	COG2963	Transposase and inactivated derivatives	116
2918251834	195	68.66	2	192	82	276	8.4e-42	137.9	COG2801	Transposase InsO and inactivated derivatives	232
2918251835	258	98.71	11	241	2	230	4.0e-43	141.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918251836	765	62.38	491	633	7	132	4.5e-18	60.1	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918251836	765	76.8	630	759	6	101	4.8e-07	23.4	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918251836	765	84.52	35	480	56	388	3.6e-69	228.8	COG0642	Signal transduction histidine kinase	336
2918251838	589	83.75	6	589	73	541	7.8e-64	210.9	COG2831	Hemolysin activation/secretion protein	554
2918251839	574	68.48	4	329	102	353	7.8e-22	72.4	COG0457	Tetratricopeptide (TPR) repeat	291
2918251840	697	13.94	161	299	92	178	4.8e-113	15.8	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918251840	697	56.73	319	692	260	613	4.8e-113	350.6	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918251841	88	38.43	1	85	47	129	6.3e-31	102.1	COG3316	Transposase (or an inactivated derivative)	215
2918251842	84	15.4	1	73	319	379	8.6e-17	55.5	COG3328	Transposase (or an inactivated derivative)	379
2918251844	640	24.64	453	640	411	548	2.5e-46	59.4	COG2831	Hemolysin activation/secretion protein	554
2918251844	640	32.5	47	319	86	267	2.5e-46	91.8	COG2831	Hemolysin activation/secretion protein	554
2918251845	638	29.77	411	638	453	644	0.0e+00	178.3	COG0323	DNA mismatch repair ATPase MutL	638
2918251845	638	52.56	1	357	1	339	0.0e+00	436.7	COG0323	DNA mismatch repair ATPase MutL	638
2918251847	143	18.36	2	139	156	267	5.5e-23	75.7	COG2905	Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains	610
2918251849	146	93.79	4	145	2	137	9.7e-52	169.3	COG3304	Uncharacterized membrane protein YccF, DUF307 family	145
2918251852	249	68.75	175	247	17	71	5.1e-09	29.4	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918251853	93	67.31	3	91	11	80	1.1e-03	12.8	COG5572	Uncharacterized membrane protein	104
2918251855	224	97.16	1	224	1	205	5.2e-55	180.8	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918251856	210	89.1	1	199	22	209	6.1e-45	147.9	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918251857	1172	38.3	32	289	2	258	0.0e+00	322.4	COG0210	Superfamily I DNA or RNA helicase	655
2918251857	1172	60.95	663	1054	256	664	0.0e+00	425.8	COG0210	Superfamily I DNA or RNA helicase	655
2918251859	297	75	13	297	76	303	8.0e-55	180.9	COG2264	Ribosomal protein L11 methylase PrmA	300
2918251860	156	95.27	1	142	5	145	1.2e-27	91.2	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
2918251861	673	25.64	75	215	11	110	1.3e-93	8.7	COG0006	Xaa-Pro aminopeptidase	384
2918251861	673	95.64	238	628	16	388	1.3e-93	297.9	COG0006	Xaa-Pro aminopeptidase	384
2918251862	121	50.86	1	121	1	118	2.8e-29	96.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918251863	356	30.88	1	97	21	87	4.2e-14	6.3	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2918251863	356	40.09	95	192	128	214	4.2e-14	40.1	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2918251864	246	93.09	32	246	10	211	2.6e-08	24.6	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2918251865	271	96.46	6	255	8	252	1.3e-87	287.8	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
2918251866	569	99.28	15	568	1	554	0.0e+00	591.4	COG0497	DNA repair ATPase RecN	557
2918251868	793	24.04	617	792	512	673	0.0e+00	140.1	COG0272	NAD-dependent DNA ligase	667
2918251868	793	85.46	18	625	5	580	0.0e+00	751.1	COG0272	NAD-dependent DNA ligase	667
2918251869	144	88.89	7	142	3	130	9.9e-31	101	COG2703	Hemerythrin	144
2918251870	312	94.35	10	310	3	286	1.6e-116	383.2	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
2918251871	617	90.8	4	353	9	324	0.0e+00	453.9	COG0206	Cell division GTPase FtsZ	338
2918251872	427	86.18	14	413	6	379	1.6e-122	403.7	COG0849	Cell division ATPase FtsA	418
2918251873	320	73.06	91	304	60	257	6.5e-39	127.4	COG1589	Cell division septal protein FtsQ	269
2918251874	314	99.37	8	310	2	317	8.0e-92	302.2	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
2918251875	312	97.96	22	308	3	290	3.8e-91	299.4	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
2918251876	472	97.83	3	466	8	458	0.0e+00	556.1	COG0773	UDP-N-acetylmuramate-alanine ligase	459
2918251878	392	98.6	7	372	1	353	1.1e-99	328.4	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
2918251879	373	96.34	7	373	6	373	7.9e-90	295.8	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
2918251880	473	98	5	459	8	448	1.6e-130	430.4	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
2918251881	361	98.77	20	361	2	323	1.0e-109	361.1	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2918251882	499	99.12	11	471	2	451	9.8e-130	427.4	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
2918251883	470	96.49	1	467	17	483	0.0e+00	455.9	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
2918251884	604	97.15	21	555	13	626	1.2e-102	330.3	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2918251886	324	98.73	1	313	4	314	5.8e-111	365.6	COG0275	16S rRNA C1402 N4-methylase RsmH	314
2918251887	165	91.1	3	152	1	133	1.1e-29	97.5	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
2918251889	192	95	1	186	8	197	1.3e-22	74.6	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
2918251890	229	88.89	2	226	28	259	7.5e-69	226.3	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
2918251891	292	95.68	3	286	10	297	1.3e-39	130.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918251892	607	98.69	5	505	4	531	0.0e+00	492.8	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918251894	261	100	77	251	1	174	7.6e-31	101.9	COG1076	DnaJ-domain-containing proteins 1	174
2918251895	187	31.55	15	149	95	153	3.3e-09	31.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918251896	1225	92.92	709	1225	2	526	0.0e+00	680.6	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
2918251896	1225	99.71	23	697	2	678	0.0e+00	781.1	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2918251897	104	39.31	3	75	77	133	1.6e-06	21.6	COG1730	Prefoldin subunit 5	145
2918251898	467	97.87	15	467	9	467	5.3e-125	412.3	COG0277	FAD/FMN-containing dehydrogenase	459
2918251900	155	97.33	1	150	2	147	7.0e-54	176.3	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
2918251901	558	99.44	5	539	3	534	0.0e+00	602.7	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918251902	468	11.07	134	245	407	468	1.0e-35	27.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918251902	468	25.36	2	149	303	444	1.0e-35	47.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918251902	468	35.71	239	466	314	513	1.0e-35	51.7	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918251904	494	38.65	17	133	127	223	2.3e-59	74.5	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918251904	494	44.22	89	210	90	200	2.3e-59	74.9	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918251904	494	54.18	238	381	60	195	2.3e-59	73.6	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918251905	420	44.39	7	200	21	190	4.8e-18	27.2	COG0477	MFS family permease	338
2918251905	420	48.83	216	417	15	201	4.8e-18	38.7	COG0477	MFS family permease	338
2918251906	209	90.59	5	205	19	201	1.8e-40	133.3	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
2918251907	257	88.05	7	248	10	230	1.7e-69	228	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
2918251908	332	56.63	104	311	23	180	4.7e-21	69.3	COG0500	SAM-dependent methyltransferase	257
2918251908	332	72.88	1	113	13	98	3.9e-15	49.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918251909	296	94.54	2	286	15	291	1.2e-98	324.3	COG0685	5,10-methylenetetrahydrofolate reductase	291
2918251911	1168	97.44	1	305	7	310	1.1e-95	314.5	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
2918251911	1168	99.77	315	1168	3	857	0.0e+00	961.5	COG1410	Methionine synthase I, cobalamin-binding domain	842
2918251912	169	92.81	12	148	8	136	3.5e-32	105.7	COG0824	Acyl-CoA thioesterase FadM	137
2918251913	169	49.8	1	164	56	180	3.6e-28	92.9	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918251914	341	90.71	136	340	17	182	8.7e-55	179.5	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918251915	362	97.39	1	361	6	341	7.3e-85	279.8	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2918251916	683	94.2	2	683	46	808	9.4e-125	410.1	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918251917	432	99.74	47	430	1	378	0.0e+00	444	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918251918	189	85.88	1	177	8	159	3.9e-33	103.9	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918251919	336	98.8	1	331	2	329	6.2e-109	358.7	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918251920	651	68.27	229	650	120	388	5.4e-50	165.8	COG0642	Signal transduction histidine kinase	336
2918251921	198	96.04	1	198	6	199	6.3e-74	242.3	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918251922	565	74.11	156	565	95	386	7.8e-74	244.2	COG0642	Signal transduction histidine kinase	336
2918251923	427	32.67	127	246	120	201	8.3e-78	76.1	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918251923	427	38.25	29	126	113	208	8.3e-78	77.6	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918251923	427	63.35	225	423	65	223	8.3e-78	116.1	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918251924	204	89.73	27	204	17	182	3.1e-57	187.9	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
2918251925	363	99.45	1	357	1	361	0.0e+00	559.4	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
2918251926	153	91.19	1	147	14	158	4.5e-39	127.7	COG2030	Acyl dehydratase	159
2918251927	197	94.26	1	197	5	201	9.9e-25	83	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918251929	247	88.79	16	247	13	210	7.8e-38	124.7	COG1843	Flagellar hook assembly protein FlgD	222
2918251932	125	53.8	24	125	14	105	2.3e-14	48.5	COG3951	Rod binding protein domain	166
2918251933	384	98.36	18	384	7	365	0.0e+00	455.5	COG1706	Flagellar basal body P-ring protein FlgI	365
2918251935	139	98.33	19	138	1	118	1.4e-38	126.6	COG1734	RNA polymerase-binding transcription factor DksA	120
2918251941	218	96.68	7	218	5	208	9.2e-55	179.9	COG2518	Protein-L-isoaspartate O-methyltransferase	209
2918251942	110	94.74	5	110	6	113	4.6e-28	92	COG0607	Rhodanese-related sulfurtransferase	110
2918251943	463	95.87	1	443	14	454	4.0e-71	234.8	COG1538	Outer membrane protein TolC	457
2918251944	230	6.41	11	38	1	15	4.4e-21	15.1	COG3827	Cell pole-organizing protein PopZ	231
2918251944	230	30.34	48	229	163	233	4.4e-21	60.7	COG3827	Cell pole-organizing protein PopZ	231
2918251945	191	17.82	4	175	28	156	3.1e-28	92.9	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2918251946	397	99.75	1	397	1	392	0.0e+00	613.1	COG3825	Uncharacterized conserved protein,  contains von Willebrand factor type A (vWA) domain	393
2918251947	416	98.03	6	414	6	404	0.0e+00	447.3	COG0303	Molybdopterin biosynthesis enzyme	404
2918251948	331	97.6	4	331	7	332	8.0e-91	298.9	COG2855	Uncharacterized membrane protein YadS	334
2918251949	295	96.35	1	294	1	290	1.2e-70	233.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918251950	1743	93.08	192	1742	113	1632	0.0e+00	1160.2	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
2918251951	696	8.31	621	696	673	733	0.0e+00	29.1	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
2918251951	696	74.8	14	612	15	563	0.0e+00	724.9	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
2918251953	507	99.38	7	507	1	481	5.1e-73	241.5	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2918251954	157	54.26	25	138	40	109	3.4e-12	40.8	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2918251955	71	97.22	1	71	3	72	4.6e-18	60.3	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
2918251956	426	95.95	7	426	13	415	1.1e-115	381.4	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
2918251958	279	96.58	7	266	3	256	1.9e-58	192.5	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2918251959	359	92.79	33	356	9	304	3.0e-47	156.2	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2918251961	1042	99.7	2	1021	2	1012	0.0e+00	1048.9	COG0841	Multidrug efflux pump subunit AcrB	1009
2918251962	399	94.36	9	389	8	375	2.5e-49	162.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918251964	616	44.17	15	245	36	179	1.0e-17	58.9	COG2203	GAF domain	175
2918251964	616	93.39	346	607	12	251	3.1e-78	256.6	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918251965	818	59.5	148	440	99	242	4.7e-22	73.5	COG2202	PAS domain	232
2918251965	818	97.27	427	614	4	181	6.3e-53	173.1	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918251967	79	12.47	3	78	4	61	2.2e-03	11.6	COG4640	Uncharacterized membrane protein YvbJ	465
2918251968	130	80.45	1	110	20	126	4.8e-15	50.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918251969	266	93.56	2	266	15	290	1.4e-36	121.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918251970	743	64.13	234	614	73	308	2.0e-30	45.4	COG0457	Tetratricopeptide (TPR) repeat	291
2918251970	743	77.72	3	268	60	345	2.0e-30	58.1	COG0457	Tetratricopeptide (TPR) repeat	291
2918251972	285	42.03	183	237	15	43	4.2e-03	9.2	COG3529	Predicted nucleic-acid-binding protein, contains Zn-ribbon domain	66
2918251973	171	89.63	10	161	6	152	1.5e-23	78.2	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
2918251974	443	78.19	23	436	4	297	4.1e-62	205.2	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918251975	341	78.51	1	307	11	273	5.4e-34	112.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918251976	258	92.25	1	256	12	249	2.5e-51	169.3	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918251977	285	97.21	19	271	4	247	7.9e-89	292.1	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918251978	265	89.53	12	257	14	244	7.6e-55	180.7	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918251979	542	97.75	1	538	7	571	2.5e-116	384.5	COG0747	ABC-type transport system, periplasmic component	556
2918251980	332	99.06	10	332	2	316	2.4e-115	380	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918251981	294	91.95	3	294	24	297	1.1e-88	291.7	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918251982	345	95.38	8	329	1	310	2.8e-118	389.2	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918251983	323	97.19	3	308	2	312	3.0e-113	373	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918251984	181	79.03	20	173	39	185	6.5e-22	73.1	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918251985	327	96.25	7	316	4	311	5.3e-95	313	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918251986	329	94.46	6	322	1	307	4.8e-114	375.3	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918251987	307	94.97	13	307	14	296	3.0e-87	287	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918251988	333	98.74	1	321	1	314	8.4e-97	319.1	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918251989	536	92.73	2	530	15	550	2.8e-98	324.8	COG0747	ABC-type transport system, periplasmic component	556
2918251990	844	94.89	3	505	17	555	2.2e-43	142.9	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918251990	844	97.01	525	827	5	296	5.2e-27	89.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918251991	487	8.26	434	487	523	571	1.5e-70	41.8	COG1982	Arginine/lysine/ornithine decarboxylase	557
2918251991	487	73.19	18	433	8	441	1.5e-70	189.5	COG1982	Arginine/lysine/ornithine decarboxylase	557
2918251992	292	97.67	1	292	1	294	7.8e-55	181.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918251993	205	84.47	20	199	5	178	6.4e-31	102.2	COG1335	Nicotinamidase-related amidase	205
2918251994	284	98.01	10	284	2	296	3.3e-50	166.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918251995	476	98.54	6	474	7	480	9.3e-114	375.7	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918251996	332	93.73	11	319	5	318	9.7e-43	141.2	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918251997	257	94.82	6	255	7	244	1.9e-89	294.1	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918251998	262	94.57	4	258	13	256	5.5e-75	246.8	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918251999	98	56.92	3	92	2	75	1.2e-16	56.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918252000	374	92.98	6	358	16	386	7.8e-24	78.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918252001	189	72.26	44	186	24	122	1.1e-10	31.9	COG1765	Uncharacterized OsmC-related protein	137
2918252002	209	90.43	9	208	16	204	1.5e-23	79.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918252003	252	92.25	1	251	12	249	8.2e-59	193.8	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918252004	427	83.88	36	366	12	292	3.7e-65	214.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918252005	260	97.21	3	251	3	246	1.8e-78	258.2	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918252006	314	95.12	27	307	11	283	5.5e-91	299.2	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2918252007	427	58.77	29	239	52	175	1.3e-06	23.3	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
2918252009	159	33.03	32	153	147	255	1.3e-23	78.4	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2918252010	80	20.3	7	80	263	329	5.2e-17	56.8	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2918252011	132	36.89	1	132	202	329	5.5e-18	60	COG3239	Fatty acid desaturase	343
2918252012	97	98.96	1	96	1	95	1.3e-40	132.3	COG0234	Co-chaperonin GroES (HSP10)	96
2918252013	544	98.91	1	537	1	544	0.0e+00	602.3	COG0459	Chaperonin GroEL (HSP60 family)	524
2918252014	87	17.93	1	83	323	393	2.9e-10	34.5	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918252015	338	79.7	5	331	7	273	2.9e-34	113.5	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918252016	332	96.12	76	329	8	255	1.3e-46	154.1	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918252018	527	98.48	14	208	2	196	1.1e-68	225.4	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2918252018	527	100	209	527	1	316	0.0e+00	506.2	COG0519	GMP synthase, PP-ATPase domain/subunit	315
2918252019	186	86.77	1	169	8	171	1.0e-10	36.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918252020	364	99.18	5	364	3	364	1.2e-61	203.6	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
2918252021	476	74.77	10	296	26	268	9.1e-33	108.9	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918252022	344	98.49	11	342	4	329	3.0e-117	386.4	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
2918252023	217	95.31	15	197	5	187	8.1e-52	170.8	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
2918252024	144	94.59	1	72	1	70	1.6e-22	73.7	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
2918252025	724	99.17	1	721	6	723	0.0e+00	886.3	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2918252026	244	99.18	5	244	2	242	8.0e-98	321.3	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
2918252027	162	97.64	11	148	2	125	5.3e-37	121.5	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
2918252028	255	90.34	6	243	7	165	8.2e-33	108.4	COG0681	Signal peptidase I	166
2918252029	234	93.64	1	233	11	231	1.8e-65	215.1	COG0571	dsRNA-specific ribonuclease	235
2918252030	356	98.32	57	353	3	295	6.7e-109	358.2	COG1159	GTPase Era, involved in 16S rRNA processing	298
2918252032	832	64.71	331	830	216	644	1.9e-105	347.8	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918252033	240	90.48	1	233	5	232	4.8e-42	138.7	COG1381	Recombinational DNA repair protein (RecF pathway)	251
2918252034	741	91.27	2	741	9	750	0.0e+00	831	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
2918252035	365	99.45	1	357	1	361	0.0e+00	549.7	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
2918252036	499	97.99	4	458	2	439	0.0e+00	694	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
2918252037	179	94.51	1	179	3	174	2.0e-69	227.5	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
2918252038	563	84	52	558	67	423	3.1e-68	225.4	COG0840	Methyl-accepting chemotaxis protein	408
2918252039	248	92.89	4	245	8	242	2.9e-80	264	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
2918252040	325	98.72	3	317	1	309	1.7e-80	265.5	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2918252041	461	92.21	4	461	29	478	0.0e+00	640.9	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
2918252042	396	98.52	12	367	4	269	1.5e-62	203.2	COG1360	Flagellar motor protein MotB	244
2918252043	168	86.49	2	167	8	167	5.7e-44	144.6	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918252047	100	70.9	1	99	23	117	2.7e-15	51.7	COG3255	Putative sterol carrier protein	134
2918252048	577	97.18	36	577	9	560	6.8e-129	425.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918252049	129	90.15	5	128	1	119	3.2e-29	96.5	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918252050	176	76.98	28	170	8	114	5.0e-14	46.8	COG0824	Acyl-CoA thioesterase FadM	137
2918252051	249	98.85	1	249	1	258	3.0e-92	303.2	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2918252052	311	98.74	2	311	2	315	6.1e-109	359.2	COG2025	Electron transfer flavoprotein, alpha subunit	313
2918252053	290	91.78	7	261	2	135	4.8e-05	14.9	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918252054	645	67.01	271	645	128	391	7.3e-33	109.7	COG0642	Signal transduction histidine kinase	336
2918252055	823	85.03	221	681	56	390	1.6e-55	184.2	COG0642	Signal transduction histidine kinase	336
2918252055	823	96.24	690	818	3	130	4.8e-22	71.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918252056	521	97.3	1	508	5	508	0.0e+00	460.8	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
2918252059	402	97.98	12	402	7	395	0.0e+00	431.6	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2918252063	352	25.6	189	268	110	173	7.0e-11	8.4	COG3063	Tfp pilus assembly protein PilF	250
2918252063	352	30.8	235	343	56	132	7.0e-11	28.7	COG3063	Tfp pilus assembly protein PilF	250
2918252064	134	18.11	3	132	64	153	2.8e-03	11.2	COG3851	Signal transduction histidine kinase, glucose-6-phosphate specific	497
2918252066	243	80.08	2	238	29	229	6.7e-51	167.1	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
2918252069	1036	99.32	1	1023	1	1023	0.0e+00	897.9	COG3696	Cu/Ag efflux pump CusA	1027
2918252074	139	98.54	1	137	2	136	2.4e-46	151.8	COG1765	Uncharacterized OsmC-related protein	137
2918252075	105	97.17	1	105	2	104	3.7e-35	115.4	COG2076	Multidrug transporter EmrE and related cation transporters	106
2918252077	106	90.43	11	104	5	89	5.9e-27	88.1	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
2918252078	1208	98.86	6	1170	11	1137	0.0e+00	1292.2	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
2918252079	324	90.62	195	318	5	120	6.6e-36	117.3	COG3603	Uncharacterized protein	128
2918252081	226	36.07	2	224	311	512	2.3e-17	51.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252083	54	88.64	13	54	6	44	2.9e-18	60.1	COG5510	Predicted small secreted protein	44
2918252084	448	93.91	5	448	18	449	7.4e-76	250.1	COG0534	Na+-driven multidrug efflux pump	455
2918252085	927	99.26	4	893	6	812	0.0e+00	1114.2	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
2918252086	188	98.11	11	172	3	158	7.7e-62	202.5	COG0669	Phosphopantetheine adenylyltransferase	159
2918252088	127	92.48	3	127	6	128	3.7e-05	18.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918252090	260	97.4	14	257	6	230	2.2e-63	208.5	COG2063	Flagellar basal body L-ring protein FlgH	230
2918252091	260	64.09	89	254	79	219	1.1e-27	91.8	COG1261	Flagella basal body P-ring formation protein FlgA	220
2918252092	261	98.87	1	261	2	263	1.5e-94	311.1	COG4786	Flagellar basal body rod protein FlgG	265
2918252093	240	99.25	1	237	1	263	4.4e-62	203	COG4786	Flagellar basal body rod protein FlgG	265
2918252094	176	93.71	9	176	11	159	2.5e-19	64.2	COG1580	Flagellar basal body-associated protein FliL	159
2918252095	358	95.8	36	357	4	322	3.0e-61	201.9	COG1868	Flagellar motor switch protein FliM	332
2918252102	327	90.28	5	324	8	295	1.3e-75	249.5	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2918252104	242	25.35	122	242	128	182	4.4e-13	25.9	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2918252104	242	30.88	40	126	14	80	4.4e-13	17	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2918252106	243	94.81	10	241	11	266	2.5e-14	43.6	COG1360	Flagellar motor protein MotB	244
2918252107	1175	47.28	608	1145	136	309	1.3e-04	12.7	COG0457	Tetratricopeptide (TPR) repeat	291
2918252108	151	67.8	1	151	62	200	2.3e-53	176	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
2918252109	632	98.09	2	632	12	626	0.0e+00	871.3	COG3158	K+ transporter	627
2918252110	252	93.57	3	250	16	248	3.7e-98	322.5	COG1338	Flagellar biosynthetic protein FliP	248
2918252113	128	88.04	25	115	7	87	1.0e-23	78.1	COG2257	Type III secretion system substrate exporter, FlhB-like	92
2918252114	134	94.07	5	133	7	133	7.0e-35	114.9	COG1815	Flagellar basal body rod protein FlgB	133
2918252115	136	100	1	135	1	138	9.0e-49	159.9	COG1558	Flagellar basal body rod protein FlgC	137
2918252116	100	80.19	1	100	21	105	1.7e-24	81.1	COG1677	Flagellar hook-basal body complex protein FliE	105
2918252117	115	94.38	1	89	1	84	2.0e-23	77.1	COG1987	Flagellar biosynthesis protein FliQ	89
2918252118	256	94.57	1	254	4	247	1.8e-54	179.5	COG1684	Flagellar biosynthesis protein FliR	258
2918252119	358	96.14	2	358	3	351	4.3e-120	395.8	COG1377	Flagellar biosynthesis protein FlhB	363
2918252120	836	67.26	290	698	127	391	7.5e-60	198.4	COG0642	Signal transduction histidine kinase	336
2918252120	836	91.73	713	836	7	128	4.7e-22	71.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918252121	346	97.94	1	280	6	290	3.2e-129	424.7	COG0468	RecA/RadA recombinase	279
2918252122	268	41.7	61	244	78	170	8.9e-05	16.6	COG1226	Voltage-gated potassium channel Kch	212
2918252123	379	93.58	12	372	12	346	6.6e-108	355.1	COG4603	ABC-type uncharacterized transport system, permease component	356
2918252124	324	98.36	2	324	5	303	8.6e-103	338.1	COG1079	ABC-type uncharacterized transport system, permease component	304
2918252125	136	92.7	1	136	9	135	1.2e-43	143.2	COG0295	Cytidine deaminase	134
2918252126	277	98.48	3	269	4	262	5.3e-79	260.2	COG0005	Purine nucleoside phosphorylase	262
2918252127	270	96.05	20	263	4	222	1.1e-64	212.5	COG0274	Deoxyribose-phosphate aldolase	228
2918252128	442	99.08	1	442	3	434	0.0e+00	512.1	COG0213	Thymidine phosphorylase	435
2918252129	304	96.68	17	302	7	297	7.8e-43	141.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918252131	368	91.53	7	346	8	342	1.0e-40	134.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918252132	291	98.34	1	290	4	299	5.1e-67	221.3	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918252133	571	97.83	7	314	5	320	1.4e-67	222.6	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918252133	571	98.03	332	568	5	253	1.4e-71	234.7	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918252134	237	97.47	2	237	2	232	4.1e-77	253.3	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918252136	601	94.83	18	454	19	440	3.5e-78	257.9	COG0038	H+/Cl- antiporter ClcA	443
2918252137	274	87.78	1	248	30	266	1.5e-96	317.7	COG2326	Polyphosphate kinase 2, PPK2 family	270
2918252138	1105	42.36	5	268	32	250	1.7e-44	75.4	COG0366	Glycosidase	505
2918252138	1105	54.74	640	926	28	310	1.7e-44	74.3	COG0366	Glycosidase	505
2918252139	295	51.52	186	288	55	122	1.8e-07	25.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918252140	363	88.05	16	336	35	314	3.1e-51	169.5	COG0657	Acetyl esterase/lipase	312
2918252141	601	99.56	142	598	2	451	0.0e+00	630.1	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
2918252143	474	97.44	41	465	9	388	2.9e-33	110.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918252144	542	89.14	1	528	39	555	0.0e+00	447.6	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2918252145	175	97.59	1	173	5	166	3.7e-69	226.1	COG0678	Peroxiredoxin	165
2918252146	329	23.64	216	328	44	117	2.1e-16	34.8	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2918252146	329	27.8	19	152	139	225	2.1e-16	22	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2918252147	360	13.1	35	171	140	180	3.6e-13	16.8	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2918252147	360	23.64	230	357	44	117	3.6e-13	26.9	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2918252148	425	98.59	1	425	1	419	0.0e+00	670.2	COG0148	Enolase	423
2918252149	261	95.93	2	261	9	291	7.1e-44	145.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918252150	515	97.68	1	509	8	513	0.0e+00	509.6	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
2918252151	290	96.17	8	289	8	283	5.7e-63	207	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2918252152	100	48.23	7	91	73	140	1.5e-21	72.3	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
2918252153	409	89.31	31	408	21	329	5.6e-69	227.4	COG1171	Threonine dehydratase	347
2918252154	231	60.82	22	194	45	193	2.5e-06	21.7	COG3904	Predicted periplasmic protein	245
2918252155	483	98.96	6	483	4	481	0.0e+00	676.7	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
2918252156	585	68.53	146	576	123	392	2.7e-49	163.3	COG0642	Signal transduction histidine kinase	336
2918252161	109	31.03	9	106	4	66	6.1e-08	27.3	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2918252167	215	85.8	7	166	19	157	1.3e-25	84.6	COG3666	Transposase	161
2918252175	110	78.4	3	109	1	98	1.5e-07	26.7	COG3293	Transposase	124
2918252176	122	93.6	2	122	5	121	2.1e-22	74.6	COG3293	Transposase	124
2918252178	197	77.52	1	163	49	217	5.5e-16	53.3	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918252179	806	14.16	513	661	537	631	3.6e-74	47.6	COG0210	Superfamily I DNA or RNA helicase	655
2918252179	806	14.31	182	305	4	99	3.6e-74	61	COG0210	Superfamily I DNA or RNA helicase	655
2918252179	806	26.23	311	545	207	382	3.6e-74	133.8	COG0210	Superfamily I DNA or RNA helicase	655
2918252181	471	97.29	1	471	11	476	0.0e+00	514.8	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918252182	79	6.29	2	22	3	20	5.0e-15	13.5	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918252182	79	19.23	16	70	232	286	5.0e-15	42.4	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918252183	266	89.66	1	223	15	222	4.7e-59	194.3	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918252184	403	96.26	1	386	15	400	6.0e-125	412	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918252185	256	95.47	1	256	7	259	2.9e-57	188.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918252186	401	98.63	15	377	4	364	1.2e-42	140.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918252187	124	93.38	1	124	7	133	1.8e-34	113.4	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918252188	414	97.56	15	413	8	406	4.3e-84	277.4	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
2918252189	386	90.88	1	385	30	368	6.1e-91	299.7	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918252190	558	98.55	1	539	5	548	0.0e+00	556.4	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918252191	281	88.59	4	278	27	290	5.7e-67	220.3	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918252192	317	98.43	1	314	2	314	2.9e-91	300.9	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918252193	521	96.02	4	519	13	567	9.1e-81	267.1	COG0747	ABC-type transport system, periplasmic component	556
2918252194	317	86.05	6	298	3	261	1.0e-42	141.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918252195	239	72.73	1	213	5	156	2.1e-23	78.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918252196	414	95.64	35	405	13	385	7.2e-65	214.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918252197	1024	99.8	2	1007	2	1013	0.0e+00	1040.3	COG0841	Multidrug efflux pump subunit AcrB	1009
2918252199	266	98.49	1	263	5	265	4.0e-81	267	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918252200	381	96.99	2	381	7	393	5.0e-67	219.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918252201	353	89.97	1	345	10	368	1.5e-25	79.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918252202	49	12.6	10	44	2	33	1.1e-06	22.9	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918252203	402	95.36	11	391	8	356	1.2e-40	134.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918252204	300	98.6	3	287	2	283	1.7e-83	274.8	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918252205	477	95.82	3	476	18	476	0.0e+00	525.3	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918252206	427	98.5	7	421	7	401	0.0e+00	490.1	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918252207	260	98.78	8	258	2	244	8.3e-47	153.9	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918252208	238	99.16	1	236	3	237	5.3e-84	275.8	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918252209	241	99.61	1	238	2	254	8.8e-85	278	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918252210	331	95.67	1	315	12	320	1.2e-67	223.2	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918252211	293	97.67	2	290	3	296	4.2e-66	218.1	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918252212	405	88.8	13	392	4	328	1.1e-57	190.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918252213	350	97.95	1	350	4	337	1.3e-81	269	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2918252214	253	99.63	1	252	1	267	6.5e-67	220.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918252215	503	98.96	18	496	3	476	0.0e+00	573.3	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918252216	406	98	1	395	8	400	5.6e-110	362.7	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918252217	388	99.5	1	388	1	397	1.1e-103	342.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918252218	411	89.24	3	411	20	475	2.4e-75	246.3	COG0427	Acyl-CoA hydrolase	501
2918252219	385	98.75	1	382	6	401	5.2e-112	369.4	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918252220	152	91.82	1	150	13	158	5.2e-44	144.1	COG2030	Acyl dehydratase	159
2918252221	285	97.19	3	285	2	278	1.8e-82	271.5	COG2301	Citrate lyase beta subunit	283
2918252222	248	97.56	4	246	4	243	1.7e-45	149.6	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918252223	542	94.37	5	534	25	560	4.0e-69	227.9	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918252224	352	97.86	28	348	6	279	3.1e-39	125.1	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2918252225	413	96.99	13	390	9	363	1.4e-35	117.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918252226	521	96.83	2	520	13	562	7.7e-106	349.2	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918252227	286	89.94	139	285	7	149	8.3e-29	93.4	COG2030	Acyl dehydratase	159
2918252228	329	100	1	323	1	331	2.4e-69	229	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918252230	385	98.5	1	385	4	398	1.5e-119	394.3	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918252231	135	90.27	8	118	3	104	1.0e-28	94.3	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
2918252232	93	97.75	4	92	3	89	3.8e-31	102.1	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
2918252233	162	100	4	162	1	158	6.2e-41	134.8	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
2918252234	546	99.01	5	536	1	501	1.5e-120	397.7	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
2918252235	114	98.25	1	114	1	112	1.2e-39	129.4	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
2918252236	995	80	800	960	24	155	3.9e-61	70.4	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
2918252236	995	89.47	7	595	2	553	0.0e+00	568.1	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2918252236	995	98.18	615	786	3	164	3.9e-61	145.2	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
2918252237	162	97.37	2	150	2	149	1.2e-29	97.7	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
2918252238	278	94.97	140	271	5	155	1.6e-26	42.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918252238	278	96.86	1	138	5	158	1.6e-26	50.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918252239	589	81.47	109	585	70	390	1.8e-45	150.7	COG0642	Signal transduction histidine kinase	336
2918252240	206	98.02	2	203	3	200	2.7e-73	240.5	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918252241	473	84.52	138	473	56	388	1.4e-32	108.7	COG0642	Signal transduction histidine kinase	336
2918252242	219	99.14	1	219	1	230	3.1e-83	273.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918252243	109	52.41	11	103	68	143	8.7e-15	50.3	COG3212	Uncharacterized membrane protein YkoI	144
2918252247	292	86.32	2	291	2	285	1.5e-115	380.5	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918252248	315	99.37	2	314	2	317	5.7e-110	362.6	COG2025	Electron transfer flavoprotein, alpha subunit	313
2918252249	249	98.85	1	249	1	258	2.6e-92	303.4	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2918252250	198	99.46	1	198	1	184	3.8e-67	220.2	COG2096	Cob(I)alamin adenosyltransferase	184
2918252255	485	98.49	41	485	3	458	0.0e+00	436.5	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2918252259	81	41.55	1	76	1	59	5.6e-17	57.2	COG5319	Uncharacterized protein	142
2918252261	286	98.51	6	272	3	266	2.7e-72	238.2	COG0345	Pyrroline-5-carboxylate reductase	266
2918252262	1258	99.22	479	1258	6	772	0.0e+00	1117.8	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
2918252262	1258	99.5	48	480	3	403	0.0e+00	501.2	COG0506	Proline dehydrogenase	391
2918252263	236	76.92	4	231	57	266	2.9e-76	251.2	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918252264	352	96.3	4	350	11	348	0.0e+00	454	COG3435	Gentisate 1,2-dioxygenase	351
2918252265	396	95.17	2	388	3	376	7.1e-69	227.8	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918252266	260	98.88	11	258	3	267	3.6e-69	228	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918252267	403	95.63	11	388	6	355	2.9e-53	175.9	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918252268	232	95.78	2	232	2	228	5.1e-77	253	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918252269	236	96.85	4	234	9	254	1.2e-75	242.4	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918252270	337	96.59	16	329	8	319	2.5e-69	228.6	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918252271	286	97.67	1	286	3	296	6.7e-71	234	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918252272	244	98.88	5	242	2	266	1.0e-52	174.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918252273	331	68.39	7	286	3	227	9.9e-61	200.4	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918252274	240	95.41	9	221	2	209	2.5e-40	132.9	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918252275	182	71.43	17	98	9	78	5.3e-25	81.2	COG4309	Uncharacterized conserved protein, DUF2249 family	98
2918252276	225	66.67	51	190	38	149	2.7e-21	69.8	COG3154	Predicted lipid carrier protein YhbT, SCP2 domain	168
2918252277	328	82	1	326	3	289	5.2e-98	322.8	COG0826	Collagenase-like protease, PrtC family	347
2918252278	307	76.86	10	301	2	270	7.4e-44	144.8	COG0826	Collagenase-like protease, PrtC family	347
2918252279	181	95.88	3	171	6	168	2.7e-60	197.3	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
2918252280	302	28.09	6	76	27	76	2.0e-14	19	COG1633	Rubrerythrin	176
2918252280	302	33.15	100	188	24	82	2.0e-14	27.8	COG1633	Rubrerythrin	176
2918252281	777	61.29	660	762	36	111	1.3e-04	14.5	COG1145	Ferredoxin	99
2918252281	777	94.61	33	516	26	481	0.0e+00	531.3	COG3901	Regulator of nitric oxide reductase transcription	482
2918252282	648	98.59	1	645	9	636	0.0e+00	1000.1	COG4263	Nitrous oxide reductase	637
2918252283	453	97.3	7	448	6	402	0.0e+00	560.9	COG3420	Nitrous oxidase accessory protein NosD, contains tandem CASH domains	408
2918252284	319	79.08	3	305	4	245	9.8e-79	259.8	COG1131	ABC-type multidrug transport system, ATPase component	293
2918252285	276	98.6	1	276	4	285	1.1e-44	148	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
2918252286	201	92.61	4	178	2	164	3.9e-59	193.8	COG4314	Nitrous oxide reductase accessory protein NosL	176
2918252287	336	85.21	10	335	38	325	1.6e-76	251.9	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
2918252288	56	51.06	1	55	1	48	8.0e-18	59.6	COG1826	Sec-independent protein translocase protein TatA	94
2918252289	418	98.23	22	418	4	392	3.2e-98	324.3	COG3213	Uncharacterized protein involved in response to NO	396
2918252290	408	94.7	12	406	18	392	1.0e-74	246.9	COG3213	Uncharacterized protein involved in response to NO	396
2918252291	259	76.45	12	222	12	209	1.2e-66	219.3	COG4525	ABC-type taurine transport system, ATPase component	259
2918252292	766	98.74	19	766	11	795	6.2e-62	198	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918252293	249	80.28	28	234	34	208	2.3e-26	87.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918252294	278	94.96	16	272	12	256	2.9e-42	139.5	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918252295	335	77.01	1	290	4	261	2.9e-19	64.1	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918252296	268	99.61	1	253	1	253	4.8e-77	253.6	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2918252297	523	91.06	1	514	10	498	0.0e+00	569.4	COG0578	Glycerol-3-phosphate dehydrogenase	532
2918252298	367	99.14	1	349	3	349	5.5e-94	310	COG3839	ABC-type sugar transport system, ATPase component	338
2918252299	363	95.14	1	356	1	333	1.1e-99	328.7	COG3839	ABC-type sugar transport system, ATPase component	338
2918252300	291	94.97	1	290	10	292	5.1e-67	221.1	COG1175	ABC-type sugar transport system, permease component	295
2918252301	289	96.82	14	289	9	282	1.6e-71	235.7	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918252302	87	89.69	1	87	10	96	2.3e-31	102.9	COG5477	Predicted small integral membrane protein	97
2918252303	591	97.74	12	533	10	442	1.6e-66	219.9	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918252304	497	98	1	496	6	496	0.0e+00	713	COG0554	Glycerol kinase	499
2918252305	214	77.73	3	213	18	216	6.0e-47	154.6	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918252307	337	96.7	21	320	4	296	2.3e-82	271.3	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2918252308	312	88.96	1	309	14	303	1.9e-70	232.2	COG3503	Uncharacterized membrane protein	323
2918252309	419	99.24	1	392	4	395	0.0e+00	443.6	COG0019	Diaminopimelate decarboxylase	394
2918252311	471	98.91	13	471	3	456	0.0e+00	664.3	COG0165	Argininosuccinate lyase	459
2918252312	222	88.67	34	201	13	145	1.4e-13	45.9	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2918252313	208	71.31	1	191	1	169	1.0e-40	134.9	COG3416	Uncharacterized protein	233
2918252314	243	92.67	1	243	16	230	1.2e-73	242.2	COG0670	Integral membrane protein, interacts with FtsH	233
2918252315	264	96.89	1	262	5	253	3.3e-21	71	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2918252316	163	84.95	2	158	21	178	4.4e-42	138.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918252317	436	98.17	1	433	4	433	0.0e+00	464.9	COG1253	Hemolysin or related protein, contains CBS domains	429
2918252320	263	88.28	29	258	12	222	3.8e-42	138.5	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918252322	436	86.24	7	408	3	353	6.3e-49	161.7	COG0644	Dehydrogenase (flavoprotein)	396
2918252323	267	70.11	45	266	31	213	6.0e-22	72.8	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918252324	274	28.41	18	262	7	108	1.3e-14	50.1	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918252325	239	97.76	2	239	6	267	4.7e-67	221.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918252326	171	93.79	9	170	4	154	1.4e-38	126.9	COG4706	Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain	161
2918252328	397	98.07	2	396	6	411	2.7e-85	281.2	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918252329	236	64.16	5	232	17	195	4.5e-09	31.6	COG0500	SAM-dependent methyltransferase	257
2918252330	274	69.03	25	266	69	253	6.5e-32	105.5	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918252331	808	97.08	3	804	15	779	0.0e+00	626.8	COG4258	Predicted exporter	788
2918252332	203	84.04	9	199	7	185	3.7e-07	24.5	COG2834	Outer membrane lipoprotein-sorting protein	211
2918252333	290	95.47	1	290	6	300	1.8e-93	307.8	COG4261	Predicted acyltransferase, LPLAT superfamily	309
2918252334	103	51.35	4	102	42	117	4.7e-14	46.7	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2918252335	465	22.64	326	464	419	543	1.9e-41	64.6	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918252335	465	34.42	120	322	176	365	1.9e-41	69.8	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918252336	210	95.52	1	199	5	196	3.3e-24	80.4	COG4648	Uncharacterized membrane protein	201
2918252337	91	93.83	5	91	2	77	1.3e-14	48.9	COG0236	Acyl carrier protein	80
2918252338	502	46.21	290	498	15	191	3.3e-41	34.1	COG0477	MFS family permease	338
2918252338	502	80.16	25	319	5	311	3.3e-41	105.6	COG0477	MFS family permease	338
2918252339	320	98.34	4	299	1	296	3.6e-45	149.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918252340	258	76.52	128	258	25	125	1.3e-19	64.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918252341	401	47.52	216	399	11	192	3.9e-22	32.1	COG0477	MFS family permease	338
2918252341	401	48.3	11	216	6	190	3.9e-22	47.4	COG0477	MFS family permease	338
2918252342	305	97.34	8	304	2	294	1.1e-75	249.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918252343	284	91.42	1	270	7	251	6.5e-54	178	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918252344	354	83.66	3	349	41	378	7.6e-47	150.2	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918252345	576	63.04	20	335	112	343	8.1e-12	40.2	COG0457	Tetratricopeptide (TPR) repeat	291
2918252346	609	97.98	43	609	12	545	0.0e+00	707.9	COG0405	Gamma-glutamyltranspeptidase	539
2918252349	353	96.22	1	343	15	370	2.4e-101	334.1	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2918252350	142	50.86	15	141	2	119	7.7e-21	69	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918252351	229	99.53	1	221	1	210	1.7e-52	172.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918252352	591	58.26	18	217	17	157	2.2e-05	18.2	COG2202	PAS domain	232
2918252352	591	82.71	204	588	5	114	6.2e-11	36.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918252353	986	59.79	840	983	6	121	1.4e-14	48.1	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
2918252353	986	67.01	539	822	129	392	5.7e-75	248.1	COG0642	Signal transduction histidine kinase	336
2918252354	315	99.07	92	302	1	214	2.8e-56	185.3	COG0811	Biopolymer transport protein ExbB/TolQ	216
2918252355	142	93.53	1	140	7	136	1.5e-43	143	COG0848	Biopolymer transport protein ExbD	137
2918252356	283	97.08	19	283	6	271	2.0e-40	133.7	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2918252357	727	98.67	2	727	11	750	0.0e+00	715.4	COG4774	Outer membrane receptor for monomeric catechols	750
2918252358	226	98.69	1	226	3	228	6.3e-102	334.7	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
2918252359	214	97.63	2	210	3	208	8.5e-60	196.4	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
2918252360	308	96.81	1	284	6	278	4.2e-80	263.5	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918252361	278	99.64	3	278	2	278	7.5e-125	410.8	COG3717	5-keto 4-deoxyuronate isomerase	278
2918252362	254	99.25	7	253	2	267	2.3e-69	228.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918252363	227	90.79	1	219	15	221	8.5e-66	216.5	COG0765	ABC-type amino acid transport system, permease component	222
2918252364	220	93.42	1	216	14	226	2.3e-69	228.3	COG0765	ABC-type amino acid transport system, permease component	222
2918252365	242	98.76	3	242	2	240	1.7e-106	349.5	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918252366	267	93.99	3	254	2	267	8.9e-46	151.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918252367	246	99.25	3	245	2	267	3.4e-62	205.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918252368	280	87.91	10	280	31	270	4.7e-91	299.9	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918252369	313	95.72	4	312	5	317	8.4e-84	275.8	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918252370	308	95.57	3	307	2	303	2.4e-58	192.3	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918252371	251	96.12	13	241	4	226	1.2e-60	199.5	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918252372	238	96.68	4	238	4	236	1.6e-66	218.9	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918252373	110	90.84	1	110	9	127	4.6e-21	69.9	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918252374	427	99.47	46	427	1	377	7.4e-126	414.6	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918252375	179	84.75	17	177	11	160	5.8e-37	121.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918252376	331	97.59	1	331	6	329	1.4e-109	361.2	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918252377	734	91.29	255	729	36	423	1.6e-53	177.4	COG0840	Methyl-accepting chemotaxis protein	408
2918252378	303	97.32	7	303	5	295	3.0e-69	227.8	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918252379	486	98.54	9	482	3	474	0.0e+00	534.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918252380	242	95.02	1	238	5	233	1.3e-64	212.6	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918252381	239	98.13	7	237	5	267	1.3e-51	170.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918252383	574	98.1	1	564	10	576	0.0e+00	595.2	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918252384	353	98.72	10	353	3	311	5.2e-81	267.1	COG2017	Galactose mutarotase or related enzyme	308
2918252385	867	91.06	369	866	36	422	2.9e-57	189.7	COG0840	Methyl-accepting chemotaxis protein	408
2918252386	1310	63.45	267	590	142	391	3.4e-116	214.1	COG0642	Signal transduction histidine kinase	336
2918252386	1310	76.14	627	1037	93	392	3.4e-116	172.1	COG0642	Signal transduction histidine kinase	336
2918252388	443	99.49	40	443	3	396	0.0e+00	545.7	COG0372	Citrate synthase	390
2918252389	337	91.33	1	335	21	315	2.5e-104	343.1	COG4111	Uncharacterized conserved protein	322
2918252390	215	98.58	3	208	2	209	5.4e-54	177.6	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918252394	1159	68.27	509	1020	122	390	1.5e-47	155.9	COG0642	Signal transduction histidine kinase	336
2918252394	1159	97.2	1	547	4	489	5.8e-83	273.7	COG0591	Na+/proline symporter	493
2918252395	559	19.84	385	553	112	187	9.5e-36	5.1	COG0477	MFS family permease	338
2918252395	559	21.93	226	330	5	88	9.5e-36	19.2	COG0477	MFS family permease	338
2918252395	559	75.46	6	268	2	290	9.5e-36	104.9	COG0477	MFS family permease	338
2918252396	355	85.16	4	264	14	254	3.8e-22	73.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918252397	1161	44	1060	1155	53	107	5.2e-04	13.6	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918252397	1161	54.98	904	1051	3	118	1.0e-14	48.2	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918252397	1161	76.14	445	887	93	392	2.5e-70	232.9	COG0642	Signal transduction histidine kinase	336
2918252398	342	96.55	5	307	7	286	6.1e-74	242.3	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
2918252399	183	96.13	2	183	3	176	1.5e-63	208.5	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
2918252400	404	67.76	19	401	109	396	1.5e-41	137.4	COG0840	Methyl-accepting chemotaxis protein	408
2918252401	261	28.32	7	235	109	187	1.1e-06	24	COG0500	SAM-dependent methyltransferase	257
2918252402	259	92.69	1	230	19	259	3.0e-48	159.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918252403	203	94.88	2	203	2	205	7.7e-34	112.2	COG0625	Glutathione S-transferase	211
2918252404	370	98.86	20	370	3	349	3.5e-69	228.6	COG0673	Predicted dehydrogenase	342
2918252405	207	99.01	4	204	2	201	1.8e-67	221.7	COG1279	Arginine exporter protein ArgO	202
2918252407	222	95.81	1	219	4	209	1.3e-42	140.7	COG0625	Glutathione S-transferase	211
2918252408	209	66.67	1	157	17	122	1.2e-05	19.8	COG4991	Uncharacterized conserved protein YraI	155
2918252409	496	97.59	34	489	3	447	1.3e-96	318.7	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918252410	157	91.27	15	137	11	125	2.5e-45	147.9	COG5349	Uncharacterized conserved protein, DUF983 family	126
2918252411	496	96.47	38	477	2	384	1.5e-98	324.8	COG0348	Polyferredoxin	386
2918252412	510	79.21	18	508	116	557	0.0e+00	439.9	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
2918252413	88	31.08	44	87	45	67	9.5e-13	14.2	COG3729	General stress protein YciG, contains tandem KGG domains	73
2918252413	88	37.84	2	46	36	63	9.5e-13	34.1	COG3729	General stress protein YciG, contains tandem KGG domains	73
2918252414	558	79.53	41	557	78	415	2.9e-57	187.8	COG0840	Methyl-accepting chemotaxis protein	408
2918252415	196	85.17	5	175	5	182	2.9e-29	96.6	COG0406	Broad specificity phosphatase PhoE	208
2918252416	383	93.22	89	361	8	282	1.9e-30	101	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918252417	517	92.91	96	502	19	385	1.3e-27	91.3	COG2814	Predicted arabinose efflux permease, MFS family	394
2918252419	133	92.48	5	131	6	128	1.5e-33	110.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918252420	308	97.51	1	308	3	315	1.9e-83	275.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918252421	288	75.67	57	288	65	291	1.7e-21	71.3	COG2342	Endo alpha-1,4 polygalactosaminidase, GH114 family (was erroneously annotated as Cys-tRNA synthetase)	300
2918252423	1023	11.34	476	552	347	401	4.9e-09	8.3	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2918252423	1023	14.43	948	1023	329	398	4.9e-09	19.4	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2918252423	1023	17.53	820	957	319	403	4.9e-09	17.2	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2918252423	1023	24.74	30	164	356	475	4.9e-09	8	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2918252424	536	66.3	10	406	102	345	8.1e-06	21.2	COG0457	Tetratricopeptide (TPR) repeat	291
2918252425	194	80.26	22	189	9	130	1.4e-09	30.5	COG5616	TolB amino-terminal domain (function unknown)	152
2918252428	524	96.33	29	512	11	404	2.9e-37	123.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918252430	83	90	2	71	7	69	1.3e-21	70.7	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2918252431	329	84.55	52	159	12	104	6.0e-16	52.7	COG3561	Phage anti-repressor protein	110
2918252437	190	85.35	13	190	16	184	2.4e-40	132.9	COG4725	N6-adenosine-specific RNA methylase IME4	198
2918252439	478	73.92	1	359	63	422	1.3e-53	177.3	COG1061	Superfamily II DNA or RNA helicase	442
2918252441	305	79.23	7	305	11	300	3.3e-31	101.4	COG4643	Uncharacterized domain associated with phage/plasmid primase	366
2918252446	107	56.77	11	105	37	124	2.2e-05	18.8	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2918252448	605	96.2	33	581	1	531	1.2e-116	384.9	COG4626	Phage terminase-like protein, large subunit, contains N-terminal HTH domain	546
2918252449	463	89.14	17	396	35	395	1.4e-43	143.6	COG4695	Phage portal protein BeeE	398
2918252450	309	85	27	210	24	193	9.0e-43	140.8	COG0740	ATP-dependent protease ClpP, protease subunit	200
2918252451	418	93.6	2	418	26	420	2.7e-53	173.8	COG4653	Predicted phage phi-C31 gp36 major capsid-like protein	422
2918252463	307	8.3	3	265	786	882	2.2e-04	13.7	COG1196	Chromosome segregation ATPase	1163
2918252467	67	4.61	11	64	645	678	8.3e-06	18.8	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
2918252472	197	92.79	3	197	8	213	3.1e-39	129.2	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
2918252475	292	65.24	60	240	67	203	2.5e-14	46.8	COG1059	Thermostable 8-oxoguanine DNA glycosylase	210
2918252476	102	36.92	6	100	8	55	1.8e-03	14	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918252480	257	44.62	45	142	2	59	4.2e-06	22.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918252482	680	58.42	230	492	151	365	1.3e-30	101	COG1223	Predicted ATPase, AAA+ superfamily	368
2918252484	79	38.46	5	76	5	54	3.7e-08	29.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918252487	448	40.38	234	439	182	307	3.5e-21	27.7	COG0501	Zn-dependent protease with chaperone function	302
2918252487	448	66.03	13	254	24	229	3.5e-21	42.7	COG0501	Zn-dependent protease with chaperone function	302
2918252495	94	88.54	4	93	4	88	6.5e-23	75.6	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
2918252496	110	92.16	6	107	8	101	5.8e-27	88.3	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
2918252497	301	98.94	5	293	1	281	1.3e-111	366.6	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
2918252498	330	90.24	7	330	33	328	2.0e-63	208.8	COG0598	Mg2+ and Co2+ transporter CorA	322
2918252499	279	97.5	1	279	6	278	4.0e-56	184.8	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
2918252501	899	87.65	742	889	15	156	2.3e-09	30.4	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918252501	899	99.84	3	634	2	634	0.0e+00	649.7	COG1042	Acyl-CoA synthetase (NDP forming)	598
2918252502	316	98.41	1	312	1	310	1.8e-90	297.8	COG0039	Malate/lactate dehydrogenase	313
2918252503	67	80	1	63	1	56	1.2e-10	35.8	COG5428	Uncharacterized protein YuzE	69
2918252505	185	98.84	1	175	1	170	5.0e-69	226.1	COG0221	Inorganic pyrophosphatase	171
2918252506	600	97.74	1	600	9	569	0.0e+00	445.5	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2918252507	107	34.1	1	107	26	129	3.6e-30	100.5	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2918252508	1175	99.22	11	1154	7	1149	0.0e+00	633.2	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2918252509	990	99.43	6	706	2	695	0.0e+00	504.1	COG3893	Inactivated superfamily I helicase	697
2918252510	248	62.17	8	242	2	236	1.5e-40	133.4	COG1208	NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins	358
2918252511	337	89.74	1	330	29	343	8.1e-72	236.6	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
2918252512	148	91.95	1	144	6	142	7.3e-39	127.5	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
2918252514	340	98.05	5	325	3	303	4.5e-71	234	COG0492	Thioredoxin reductase	305
2918252516	243	98.71	5	239	2	230	3.2e-82	270	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918252517	463	84.26	57	463	56	387	2.5e-54	180	COG0642	Signal transduction histidine kinase	336
2918252518	764	11.17	701	754	347	390	2.9e-37	26	COG0642	Signal transduction histidine kinase	336
2918252518	764	48.98	472	698	129	321	2.9e-37	100.9	COG0642	Signal transduction histidine kinase	336
2918252519	1209	21.55	772	829	3	52	4.8e-29	14.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918252519	1209	49.14	923	1059	2	115	4.8e-29	79	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918252519	1209	66.75	462	761	128	390	6.0e-79	261.2	COG0642	Signal transduction histidine kinase	336
2918252519	1209	71.2	1090	1206	20	108	3.9e-13	42.9	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918252520	344	88.69	5	276	11	261	8.7e-29	94.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918252521	153	95.97	2	153	6	148	2.1e-56	184.4	COG0756	dUTPase	148
2918252522	425	99.25	6	424	2	399	0.0e+00	435.1	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
2918252523	476	96.79	4	475	6	457	0.0e+00	539.9	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918252524	69	98.51	1	68	1	66	1.5e-32	106.2	COG1278	Cold shock protein, CspA family	67
2918252525	265	60	159	256	13	87	4.4e-09	30.9	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918252525	265	92.48	11	140	6	128	7.6e-38	122.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918252526	405	98.23	9	405	3	391	0.0e+00	660.2	COG0133	Tryptophan synthase beta chain	396
2918252527	285	98.49	12	282	3	263	4.8e-96	315.5	COG0159	Tryptophan synthase alpha chain	265
2918252528	316	91.84	1	292	18	287	9.1e-121	397.2	COG0777	Acetyl-CoA carboxylase beta subunit	294
2918252529	455	96.27	17	455	10	422	1.5e-118	389.9	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
2918252531	73	74.32	3	71	4	58	2.0e-18	61.1	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
2918252537	187	96.91	25	184	4	160	8.6e-53	172.5	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
2918252538	221	99.55	1	221	2	221	1.4e-78	258.1	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
2918252539	232	92.34	3	209	6	198	3.3e-64	210.9	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
2918252540	560	99.08	11	560	5	543	0.0e+00	580.7	COG2985	Uncharacterized membrane protein YbjL, putative transporter	544
2918252541	269	98.05	9	265	4	254	0.0e+00	438.3	COG4598	ABC-type histidine transport system, ATPase component	256
2918252542	280	96.11	1	280	6	277	2.2e-64	212.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918252543	234	98.7	7	234	3	229	1.2e-85	281.2	COG4215	ABC-type arginine transport system, permease component	230
2918252544	229	99.56	1	227	1	227	1.1e-88	291.2	COG4160	ABC-type arginine/histidine transport system, permease component	228
2918252545	243	80.85	1	237	40	267	6.3e-66	217.3	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
2918252546	77	52.24	1	67	7	41	1.2e-11	39.4	COG3114	Heme exporter protein D	67
2918252547	165	94.77	1	149	1	145	4.3e-54	176.8	COG2332	Cytochrome c-type biogenesis protein CcmE	153
2918252548	663	99.07	1	656	2	641	0.0e+00	801.2	COG1138	Cytochrome c biogenesis factor	648
2918252549	178	95.33	12	154	4	146	2.1e-12	42.1	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2918252550	161	96.73	1	159	5	152	6.5e-48	156.6	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
2918252551	465	51.56	290	462	122	270	6.7e-81	73.7	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
2918252551	465	96.54	1	285	1	279	6.7e-81	198.9	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
2918252552	271	98.13	1	243	4	266	1.0e-56	186.4	COG1912	S-adenosylmethionine hydrolase (SAM-hydroxide adenosyltransferase)	268
2918252553	412	91.8	157	412	8	231	5.3e-48	157.8	COG2114	Adenylate cyclase, class 3	227
2918252554	184	84.95	102	184	6	84	9.1e-32	102.4	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
2918252555	703	99.71	1	692	2	693	0.0e+00	1039.6	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
2918252556	89	100	1	89	1	89	7.1e-39	126.4	COG0184	Ribosomal protein S15P/S13E	89
2918252557	312	86.77	2	312	4	272	7.1e-100	329.1	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
2918252558	183	96.64	3	131	4	118	2.1e-29	96.4	COG0858	Ribosome-binding factor A	118
2918252559	935	99.29	430	935	3	559	0.0e+00	542.6	COG0532	Translation initiation factor IF-2, a GTPase	509
2918252560	266	90.53	45	140	3	88	8.9e-23	74.5	COG2740	Predicted RNA-binding protein YlxR, DUF448 family	95
2918252561	512	26.67	3	60	80	115	4.8e-03	3.4	COG0355	FoF1-type ATP synthase, epsilon subunit	135
2918252561	512	50.37	356	439	62	129	4.8e-03	8.3	COG0355	FoF1-type ATP synthase, epsilon subunit	135
2918252561	512	64.84	60	152	14	72	3.4e-04	14.4	COG2002	Bifunctional DNA-binding transcriptional regulator of stationary/sporulation/toxin gene expression and antitoxin component of the YhaV-PrlF toxin-antitoxin module	89
2918252561	512	98.49	154	354	2	197	1.7e-84	275.9	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
2918252562	163	95.45	1	152	7	153	1.1e-47	156.4	COG0779	Ribosome maturation factor RimP	153
2918252563	105	91.51	1	99	2	98	2.7e-17	57.4	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
2918252564	243	96.04	12	242	8	225	2.5e-51	169	COG0220	tRNA G46 methylase TrmB	227
2918252565	389	98.71	2	389	4	387	0.0e+00	555.6	COG0192	S-adenosylmethionine synthetase	388
2918252566	164	59.23	29	156	2	78	4.8e-16	54.3	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918252567	529	96.92	15	529	11	514	1.2e-127	421.2	COG0815	Apolipoprotein N-acyltransferase	518
2918252568	311	59.59	23	306	173	433	4.3e-87	287.2	COG1253	Hemolysin or related protein, contains CBS domains	429
2918252569	180	93.51	2	160	9	152	5.9e-49	160.2	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
2918252570	349	95.29	2	338	12	335	4.2e-125	411.9	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
2918252571	471	99.09	1	453	3	439	0.0e+00	500	COG0621	tRNA A37 methylthiotransferase MiaB	437
2918252572	204	95.32	1	170	4	166	7.8e-40	131.1	COG3153	Predicted N-acetyltransferase YhbS	171
2918252573	130	97.62	2	127	2	124	6.3e-53	172.7	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
2918252574	221	94.92	20	216	9	195	4.4e-80	262.2	COG0302	GTP cyclohydrolase I	195
2918252575	160	98.06	5	160	2	153	2.5e-48	158.4	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
2918252577	238	76.82	9	238	44	265	2.2e-63	208.8	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2918252578	779	28.36	371	498	37	133	6.8e-59	12	COG0668	Small-conductance mechanosensitive channel	316
2918252578	779	86.26	489	779	42	336	6.8e-59	194.6	COG0668	Small-conductance mechanosensitive channel	316
2918252579	156	84.4	1	142	3	121	2.0e-44	144.8	COG5478	Low affinity Fe/Cu permease	141
2918252580	180	90.85	10	171	15	163	1.8e-49	162.1	COG5488	Uncharacterized membrane protein	164
2918252582	215	97.16	5	214	4	208	3.0e-80	262.9	COG0177	Endonuclease III	211
2918252583	281	68.49	146	272	25	124	3.0e-14	47.4	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
2918252584	225	80.4	2	220	40	240	1.0e-24	81.2	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
2918252585	418	99.03	1	418	2	411	0.0e+00	537.9	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918252586	167	88.33	1	116	1	106	1.4e-35	116	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2918252587	331	96.84	7	328	1	306	2.3e-69	228.4	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918252588	162	23.71	2	129	24	124	1.9e-06	21.8	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
2918252590	305	98.46	8	293	2	256	3.1e-55	181.9	COG0730	Uncharacterized membrane protein YfcA	258
2918252592	167	76.73	14	155	8	129	4.2e-10	35.2	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918252593	248	98.28	21	247	3	230	5.2e-93	305.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918252594	272	97.64	19	272	7	254	1.9e-126	415.2	COG1117	ABC-type phosphate transport system, ATPase component	253
2918252595	421	14.97	11	90	11	54	6.2e-83	4.5	COG0581	ABC-type phosphate transport system, permease component	292
2918252595	421	88.44	132	421	35	294	6.2e-83	270.2	COG0581	ABC-type phosphate transport system, permease component	292
2918252596	460	96.18	148	459	13	314	1.7e-100	330.1	COG0573	ABC-type phosphate transport system, permease component	310
2918252597	347	92.92	1	332	17	318	2.7e-64	212.1	COG0226	ABC-type phosphate transport system, periplasmic component	318
2918252598	520	88.32	61	505	43	390	2.4e-76	252.4	COG0642	Signal transduction histidine kinase	336
2918252599	214	81.54	18	143	2	107	3.7e-19	64	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918252600	176	79.01	6	160	27	154	4.6e-12	40.9	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918252601	754	95.02	1	432	14	433	0.0e+00	568	COG0281	Malic enzyme	432
2918252601	754	97.86	432	752	3	322	1.9e-102	337	COG0280	Phosphotransacetylase	327
2918252602	239	96.54	1	237	8	230	2.7e-94	309.5	COG0689	Ribonuclease PH	230
2918252603	199	96.41	9	199	3	190	3.8e-66	217.1	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
2918252604	385	89.52	2	385	38	413	9.7e-115	378.2	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
2918252605	164	93.53	2	161	2	160	3.7e-42	138.7	COG0262	Dihydrofolate reductase	167
2918252606	308	98.86	39	300	2	262	9.5e-72	236.6	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918252607	265	97.73	9	263	3	260	1.3e-82	272.1	COG1192	Cellulose biosynthesis protein BcsQ	259
2918252608	209	83.26	3	195	13	191	1.9e-48	159.3	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
2918252609	606	95.51	1	604	26	621	0.0e+00	811.1	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
2918252610	443	99.34	1	443	4	454	0.0e+00	470.7	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
2918252611	119	87.5	51	118	2	57	9.4e-21	68.3	COG3411	(2Fe-2S) ferredoxin	64
2918252613	703	98.97	17	696	3	672	0.0e+00	780.5	COG1331	Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains	667
2918252614	163	66.67	8	147	55	166	6.6e-43	141.3	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2918252615	324	99.4	2	324	2	330	9.9e-94	309	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918252616	227	82.68	1	226	17	226	4.8e-57	188.4	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2918252617	219	97.01	1	199	2	196	4.1e-50	164.9	COG0237	Dephospho-CoA kinase	201
2918252618	279	95.77	2	278	2	273	8.3e-84	275.6	COG0169	Shikimate 5-dehydrogenase	283
2918252619	205	96.91	8	205	3	190	6.5e-50	163.7	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
2918252620	284	98.17	1	270	1	268	4.6e-99	326	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
2918252621	362	96.88	10	361	8	349	3.1e-112	369.6	COG0407	Uroporphyrinogen-III decarboxylase	352
2918252622	356	97.51	8	330	6	318	1.9e-95	314.1	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
2918252623	142	95.97	1	142	7	149	1.0e-59	195.8	COG1981	Uncharacterized membrane protein	149
2918252624	418	98.82	1	418	4	420	0.0e+00	720.1	COG1158	Transcription termination factor Rho	422
2918252625	167	91.08	7	165	10	152	1.1e-50	165.9	COG1952	Preprotein translocase subunit SecB	157
2918252626	206	73.91	1	189	5	123	4.5e-39	128.3	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
2918252627	224	82.56	1	223	47	278	4.7e-49	162.1	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
2918252628	408	81.53	10	399	68	376	6.0e-102	336.2	COG2821	Membrane-bound lytic murein transglycosylase	373
2918252629	123	75.18	8	122	2	107	2.7e-30	99.7	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2918252630	121	97.92	21	119	1	94	7.3e-33	107.4	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
2918252631	262	99.22	1	253	1	255	2.6e-116	382	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
2918252632	248	98.34	1	241	2	238	4.8e-90	295.5	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
2918252633	182	69.84	12	170	40	171	2.2e-17	58.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918252634	214	99.51	1	214	1	203	2.9e-77	253.8	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
2918252635	207	98.97	7	203	3	195	6.3e-86	281.7	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
2918252637	187	97.75	13	187	2	175	8.2e-83	271	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
2918252638	438	99.55	2	438	3	444	0.0e+00	684.8	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
2918252639	396	82.99	14	395	63	389	5.7e-68	224.7	COG0642	Signal transduction histidine kinase	336
2918252640	132	80.77	3	131	2	106	2.6e-15	52	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918252641	190	95.65	1	188	7	182	1.2e-41	137.5	COG2840	DNA-nicking endonuclease, Smr domain	184
2918252642	181	98.35	2	179	2	180	2.9e-51	168.6	COG1514	2'-5' RNA ligase	180
2918252643	347	100	1	347	1	320	3.8e-110	362.1	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918252644	389	88.95	36	389	40	385	2.4e-44	146.2	COG4398	Small ligand-binding sensory domain FIST	389
2918252645	211	95.93	8	206	7	218	9.0e-44	144.6	COG2755	Lysophospholipase L1 or related esterase	216
2918252646	262	98.25	14	239	4	227	1.2e-98	323.7	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
2918252647	864	99.28	17	864	6	828	0.0e+00	795.6	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
2918252648	241	93.1	5	241	15	230	9.7e-75	245.6	COG0670	Integral membrane protein, interacts with FtsH	233
2918252649	377	90.16	193	373	16	180	5.1e-44	144.5	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918252650	385	99.74	1	382	1	384	0.0e+00	486.8	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2918252651	641	99.17	1	600	5	605	0.0e+00	873.7	COG0443	Molecular chaperone DnaK (HSP70)	579
2918252655	121	90.23	1	121	6	125	1.1e-34	113.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918252656	198	89.29	1	185	20	194	3.2e-56	185	COG0576	Molecular chaperone GrpE (heat shock protein)	193
2918252657	346	98.26	2	346	2	340	4.0e-111	366.5	COG1420	Transcriptional regulator of heat shock response	346
2918252658	248	97.99	1	248	3	246	8.3e-63	206.8	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
2918252659	511	98.17	17	509	5	487	0.0e+00	611.9	COG0606	Predicted ATPase with chaperone activity	490
2918252660	78	28.57	1	76	64	101	3.5e-05	19	COG3743	 Predicted 5' DNA nuclease, flap endonuclease-1-like, helix-3-turn-helix (H3TH) domain	133
2918252661	519	95.25	67	499	8	288	2.8e-26	85.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918252663	124	55.64	11	120	24	97	1.1e-14	48.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918252664	205	89.37	3	200	3	187	4.9e-33	109.3	COG2039	Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)	207
2918252665	332	97.79	1	311	7	316	6.7e-106	348.8	COG0180	Tryptophanyl-tRNA synthetase	314
2918252666	315	98.41	3	314	3	312	7.1e-89	292.3	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2918252667	277	89.26	7	276	11	251	4.5e-42	138.7	COG2912	Regulator of sirC expression, contains transglutaminase-like and TPR domains	269
2918252668	122	95.61	11	122	4	112	4.2e-30	98.7	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
2918252669	320	98.53	28	302	3	270	1.0e-92	304.7	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
2918252670	361	90.71	3	349	9	340	3.2e-28	93.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918252671	341	92.22	5	339	9	316	1.6e-51	170	COG1466	DNA polymerase III, delta subunit	334
2918252672	186	98.26	19	185	3	171	1.2e-26	88.3	COG5468	Predicted secreted (periplasmic) protein	172
2918252673	856	99.88	1	856	2	823	0.0e+00	1025.3	COG0495	Leucyl-tRNA synthetase	814
2918252678	242	98.25	19	239	4	228	4.7e-73	240.3	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
2918252679	181	68.66	7	168	65	213	2.9e-51	168.7	COG3786	L,D-peptidoglycan transpeptidase YkuD, ErfK/YbiS/YcfS/YnhG family	217
2918252681	394	29.06	119	200	141	199	8.5e-05	11.1	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
2918252681	394	33	16	88	4	70	8.5e-05	3.6	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
2918252681	394	98.47	200	394	3	195	3.1e-68	223.8	COG0807	GTP cyclohydrolase II	193
2918252683	231	98.71	5	231	1	229	2.0e-60	198.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918252685	286	97.8	12	286	6	272	1.9e-43	143.3	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2918252686	283	86.49	13	193	24	183	4.8e-43	141.7	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
2918252687	264	99.61	1	264	1	258	1.3e-73	242.2	COG0708	Exonuclease III	261
2918252688	227	77.29	13	227	59	269	4.9e-76	250.5	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918252689	164	90.98	36	163	7	127	8.0e-29	94.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918252690	254	98.77	2	250	2	242	2.4e-74	244.5	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
2918252691	211	93.55	14	197	11	184	8.2e-31	101.4	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
2918252692	222	84.04	1	217	27	205	4.8e-24	79.5	COG2834	Outer membrane lipoprotein-sorting protein	211
2918252693	422	99.49	18	411	2	392	1.9e-103	341.5	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918252694	112	100	1	112	1	112	9.2e-49	159.3	COG0347	Nitrogen regulatory protein PII	112
2918252695	419	97.47	21	419	6	391	4.1e-67	221.5	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918252696	868	19.42	54	249	18	198	0.0e+00	24.6	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2918252696	868	57.3	245	867	393	926	0.0e+00	796.2	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2918252698	261	92.75	1	260	10	265	6.9e-81	266.2	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2918252699	260	98.43	10	245	4	253	4.0e-76	250.2	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
2918252700	337	95.72	5	337	13	325	2.7e-114	376.3	COG4531	ABC-type Zn2+ transport system, periplasmic component/surface adhesin	318
2918252701	265	98.88	1	265	3	266	2.4e-94	310.4	COG0289	Dihydrodipicolinate reductase	266
2918252702	519	34.32	26	206	16	142	9.6e-74	18.3	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2918252702	519	51.08	282	512	170	358	9.6e-74	223.1	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2918252703	209	98.56	1	206	1	205	3.1e-59	194.3	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918252704	588	86.56	7	297	42	305	4.1e-54	178.1	COG5309	Exo-beta-1,3-glucanase,  GH17 family	305
2918252705	257	98.88	1	254	4	268	4.7e-59	194.6	COG1018	Ferredoxin-NADP reductase	266
2918252706	480	78.26	1	88	4	57	1.6e-08	27.5	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2918252706	480	99.1	143	475	3	331	0.0e+00	437.4	COG3800	Predicted transcriptional regulator	332
2918252707	425	37.29	242	424	297	472	0.0e+00	259.5	COG2224	Isocitrate lyase	433
2918252707	425	52.75	2	245	12	260	0.0e+00	342.1	COG2224	Isocitrate lyase	433
2918252708	187	96.43	6	181	3	191	3.4e-20	67.3	COG0693	Putative intracellular protease/amidase	188
2918252709	571	87.06	20	569	43	412	2.6e-53	170.6	COG0840	Methyl-accepting chemotaxis protein	408
2918252710	504	93.91	65	502	21	390	9.8e-68	224.1	COG0642	Signal transduction histidine kinase	336
2918252711	549	38.04	13	220	24	233	3.9e-65	55.9	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918252711	549	47.46	219	497	286	547	3.9e-65	151	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918252712	247	65.1	45	247	95	288	1.6e-30	101	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918252713	253	68.87	38	248	94	312	2.8e-16	51.6	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918252714	749	73.81	41	462	71	428	1.0e-52	173.7	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918252714	749	90.18	521	747	8	209	4.2e-33	108.9	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
2918252715	270	97.28	35	270	6	255	1.4e-52	173.3	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918252716	407	98.07	1	407	2	408	0.0e+00	631.3	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
2918252717	386	73.35	21	386	99	387	1.1e-32	108.9	COG0642	Signal transduction histidine kinase	336
2918252718	312	87.99	1	312	28	342	3.5e-86	283.8	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
2918252719	360	98.77	14	336	3	322	3.8e-105	346	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
2918252720	389	92.8	1	389	13	360	8.9e-92	302.8	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2918252721	314	98.75	1	309	3	319	2.6e-54	179.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918252722	246	94.94	3	245	9	252	1.8e-66	218.2	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
2918252723	195	95.05	2	192	10	201	4.6e-48	157.8	COG1573	Uracil-DNA glycosylase	202
2918252724	116	83.82	1	116	20	133	9.0e-43	140.1	COG3824	Predicted Zn-dependent protease, minimal metalloprotease (MMP)-like domain	136
2918252725	100	91.09	1	99	5	96	1.4e-28	93.6	COG2154	Pterin-4a-carbinolamine dehydratase	101
2918252726	500	94.64	4	498	16	562	5.7e-109	360	COG0747	ABC-type transport system, periplasmic component	556
2918252727	315	99.06	1	315	2	316	9.0e-108	355.1	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918252728	277	90.6	2	273	27	296	8.2e-83	272.4	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918252730	164	71.51	5	151	48	175	1.1e-24	81.3	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
2918252733	543	88.47	55	538	48	423	1.6e-64	213	COG0840	Methyl-accepting chemotaxis protein	408
2918252734	594	98.95	16	593	3	570	0.0e+00	625.7	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
2918252735	99	97.75	12	99	2	88	6.3e-29	94.7	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
2918252736	132	89.51	1	132	1	128	2.4e-41	135.6	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
2918252737	334	99.3	20	302	2	285	1.6e-95	314.4	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
2918252738	149	41.88	1	137	136	264	6.1e-31	102.5	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
2918252740	532	87.56	122	532	44	388	3.0e-60	199.7	COG0642	Signal transduction histidine kinase	336
2918252741	232	98.28	3	232	2	229	1.9e-74	244.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918252742	242	93.12	2	235	9	238	6.2e-18	59.2	COG0748	Putative heme iron utilization protein	245
2918252743	607	98.03	1	599	12	607	0.0e+00	900.9	COG1274	Phosphoenolpyruvate carboxykinase, GTP-dependent	608
2918252744	139	97.2	1	137	4	142	1.5e-46	152.8	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2918252745	174	72.18	49	168	2	97	9.4e-28	91.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918252746	286	97.75	1	284	3	263	5.5e-87	285.7	COG1291	Flagellar motor component MotA	266
2918252749	447	83.86	45	415	37	301	5.9e-54	178.6	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2918252750	259	84.72	9	259	4	258	1.4e-73	242.7	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918252751	245	99.58	14	245	2	237	4.0e-87	285.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918252752	251	99.21	2	248	3	254	2.6e-87	287	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918252753	415	90.71	9	388	6	337	1.4e-46	153.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918252754	557	78.32	71	556	117	553	0.0e+00	450.1	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
2918252755	411	98.75	8	411	6	401	0.0e+00	434	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918252756	259	93.26	1	259	16	278	1.2e-68	226.3	COG0447	1,4-Dihydroxy-2-naphthoyl-CoA synthase	282
2918252757	559	96.65	21	550	12	560	9.9e-80	262.9	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918252758	255	97.74	1	252	7	265	4.3e-79	260.3	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918252759	251	98.13	4	249	5	267	7.4e-54	177.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918252760	390	97.49	6	390	5	393	3.6e-118	389.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918252761	291	86.63	2	289	2	286	4.2e-108	356	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918252763	379	92.77	1	373	6	377	1.6e-103	341.2	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918252764	328	100	1	328	1	331	1.3e-94	312	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918252765	518	35.87	389	511	153	270	2.2e-120	62.5	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918252765	518	85.71	15	330	6	287	2.2e-120	332.1	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918252766	400	100	1	400	1	394	0.0e+00	481.1	COG0183	Acetyl-CoA acetyltransferase	392
2918252767	379	84.66	84	376	45	309	8.3e-53	173.6	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2918252768	138	80.9	13	94	2	73	1.0e-08	29.9	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
2918252769	749	98.39	26	749	5	737	0.0e+00	487.6	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918252770	159	97.44	1	159	4	155	1.5e-60	198	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918252771	399	97.47	7	398	5	389	1.7e-77	255.1	COG2814	Predicted arabinose efflux permease, MFS family	394
2918252772	302	98.67	9	302	1	297	1.5e-48	160.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918252773	287	78.03	158	286	23	125	1.8e-24	80.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918252774	155	98.52	21	155	2	134	4.0e-47	154.4	COG4954	Uncharacterized protein	135
2918252775	253	47.25	2	120	27	129	2.1e-31	69.6	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918252775	253	51.83	127	253	24	136	2.1e-31	32.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918252776	456	97.84	4	450	3	455	4.9e-129	425.6	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2918252777	1181	93.63	735	943	4	194	2.0e-26	87	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
2918252777	1181	98.29	30	716	3	635	0.0e+00	541	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
2918252780	191	79.9	1	180	3	157	1.2e-40	134.2	COG3758	Various environmental stresses-induced protein Ves (function unknown)	193
2918252781	513	92.9	283	500	13	182	3.2e-45	148.5	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918252782	174	38.84	13	136	135	228	4.8e-09	31	COG2202	PAS domain	232
2918252783	436	78.12	3	430	92	423	3.6e-46	147	COG0840	Methyl-accepting chemotaxis protein	408
2918252784	454	97.84	4	442	3	455	0.0e+00	444.8	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2918252787	567	99.81	1	543	1	534	0.0e+00	508.3	COG1283	Na+/phosphate symporter	533
2918252788	139	70.37	1	139	14	146	9.0e-04	13.4	COG3945	Hemerythrin-like domain	189
2918252789	391	88.06	150	391	1	236	3.0e-69	227.9	COG1018	Ferredoxin-NADP reductase	266
2918252789	391	97.33	1	150	1	146	1.4e-55	181.9	COG1017	Hemoglobin-like flavoprotein	150
2918252790	527	89.64	6	526	54	546	0.0e+00	535.6	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2918252792	812	89.74	1	812	68	863	0.0e+00	791	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
2918252793	160	99.37	1	155	1	157	4.1e-47	154.8	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918252794	331	95.04	9	324	8	333	1.6e-65	215.9	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918252795	387	90.8	2	387	38	412	2.5e-114	377.1	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2918252798	367	36.97	168	337	99	186	4.2e-01	2.9	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
2918252799	265	98.88	4	259	3	267	1.0e-70	232.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918252800	453	97.32	15	453	8	442	0.0e+00	476.8	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918252801	318	97.67	14	305	2	295	5.8e-42	139.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918252803	335	85.37	1	319	5	290	5.4e-44	145.5	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918252804	646	68.64	159	645	195	682	9.0e-60	194.4	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918252805	749	95.22	14	740	4	680	1.2e-83	269.2	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918252807	325	43.83	6	167	63	133	7.5e-05	18.5	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918252810	238	99.16	2	237	2	236	6.3e-94	308.2	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918252811	264	99.21	1	252	3	254	1.5e-104	343.5	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918252812	280	90.71	2	280	28	320	4.2e-73	241	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918252813	293	98.01	1	292	5	299	2.7e-66	218.8	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918252814	375	93.44	12	373	5	346	1.1e-68	226.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918252815	527	51.7	25	395	2	244	9.7e-42	138.4	COG0515	Serine/threonine protein kinase	384
2918252816	288	92.28	37	287	12	262	1.8e-41	136.7	COG0631	Serine/threonine protein phosphatase PrpC	262
2918252818	884	15.51	371	502	251	348	3.2e-30	43.1	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2918252818	884	31.65	549	870	388	587	3.2e-30	54.3	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2918252819	843	64.92	436	842	115	362	1.8e-12	40	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
2918252830	971	11.04	353	551	277	331	4.2e-21	3.6	COG2319	WD40 repeat	466
2918252830	971	22.49	178	317	261	372	4.2e-21	22.1	COG2319	WD40 repeat	466
2918252830	971	30.52	45	206	268	419	4.2e-21	50.5	COG2319	WD40 repeat	466
2918252831	308	55.78	12	296	84	194	1.7e-16	55.5	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918252834	439	87.32	54	439	49	406	5.4e-44	145.3	COG4826	Serine protease inhibitor	410
2918252835	470	56.78	272	470	84	196	4.8e-31	102.8	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918252836	682	93.99	283	678	9	352	2.2e-81	267	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918252837	379	77.11	21	337	1	293	2.3e-31	103.9	COG4249	Uncharacterized protein, contains caspase domain	380
2918252838	405	89.51	25	404	38	404	5.3e-29	95.6	COG4826	Serine protease inhibitor	410
2918252839	175	63.82	16	175	71	197	1.1e-25	85.8	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918252848	211	33.93	19	206	359	548	1.7e-12	36.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252852	386	45.74	1	276	23	253	5.6e-14	46.4	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2918252853	285	74.71	27	247	53	247	4.9e-15	49.2	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918252854	514	98.39	1	503	6	494	1.3e-96	319.2	COG1233	Phytoene dehydrogenase-related protein	487
2918252855	499	94.97	1	476	21	492	2.5e-91	301.7	COG1233	Phytoene dehydrogenase-related protein	487
2918252856	431	81	1	384	89	476	1.2e-76	252.5	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918252857	164	98.04	8	164	2	151	5.6e-46	151.1	COG3918	Uncharacterized membrane protein	153
2918252858	222	92.67	1	222	9	223	7.9e-57	187.1	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918252859	337	98.53	1	337	2	337	0.0e+00	475.5	COG3938	Proline racemase	341
2918252860	314	96.99	4	298	5	294	4.0e-86	283	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918252861	412	97.68	1	412	5	383	2.4e-64	207.2	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918252862	716	99.16	2	709	6	710	0.0e+00	850.7	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918252863	485	96.92	43	476	11	388	2.2e-36	120.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918252864	6408	6.79	816	857	423	460	0.0e+00	18.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	9.29	850	925	406	457	0.0e+00	30.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	9.82	4517	4581	399	453	0.0e+00	32.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	11.07	166	223	399	460	0.0e+00	19.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	15.54	5510	5624	401	487	0.0e+00	39.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	16.96	5753	5873	391	485	0.0e+00	33.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	17.86	5101	5281	355	454	0.0e+00	44.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	24.11	4355	4535	317	451	0.0e+00	39.7	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	24.46	697	814	308	444	0.0e+00	54.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	25.18	5846	6014	321	461	0.0e+00	51	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	26.07	5268	5419	338	483	0.0e+00	41	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	27.32	4531	4688	308	460	0.0e+00	55.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	27.32	5340	5535	308	460	0.0e+00	61.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	27.5	5976	6161	310	463	0.0e+00	59.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	27.86	1703	1888	318	473	0.0e+00	30.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	28.93	907	1094	313	474	0.0e+00	41.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	30.18	1861	2010	275	443	0.0e+00	36.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	30.71	1155	1320	289	460	0.0e+00	29.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	31.79	1071	1242	266	443	0.0e+00	29	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	32.14	4868	5083	251	430	0.0e+00	52.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	32.14	5597	5763	264	443	0.0e+00	55.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	32.5	2	180	280	461	0.0e+00	76.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	33.04	178	407	316	500	0.0e+00	20.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	34.64	1308	1481	268	461	0.0e+00	28.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	34.64	1465	1637	266	459	0.0e+00	26.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	34.82	1623	1819	267	461	0.0e+00	24.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	36.43	3702	3916	258	461	0.0e+00	83.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	41.79	4172	4397	251	484	0.0e+00	70.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	43.39	6140	6395	314	556	0.0e+00	49	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	46.79	4652	4912	200	461	0.0e+00	58.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	52.5	3894	4177	198	491	0.0e+00	80	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	53.21	265	709	162	459	0.0e+00	60.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	53.21	3253	3683	175	472	0.0e+00	12.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252864	6408	57.14	3395	3807	116	435	0.0e+00	47.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918252865	180	58.26	4	169	13	139	1.3e-17	58.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918252866	979	76.37	389	978	168	710	0.0e+00	466.7	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918252867	750	99.3	21	750	3	708	0.0e+00	646.4	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918252868	421	65.06	38	350	60	288	1.9e-24	80.2	COG1566	Multidrug resistance efflux pump	352
2918252870	238	82.58	31	220	10	227	5.0e-18	48.8	COG1192	Cellulose biosynthesis protein BcsQ	259
2918252873	298	99	4	293	1	298	2.2e-56	186.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918252874	297	99.3	2	293	3	286	2.7e-108	356.2	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918252875	381	98.25	1	381	1	392	1.0e-126	417.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918252876	499	99.37	5	486	2	477	0.0e+00	524.7	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918252879	156	39.58	1	137	1	112	5.4e-21	68.7	COG3649	CRISPR/Cas system type I-B associated protein Csh2, Cas7 group, RAMP superfamily	283
2918252880	216	14.13	1	44	126	165	1.9e-14	7.8	COG3649	CRISPR/Cas system type I-B associated protein Csh2, Cas7 group, RAMP superfamily	283
2918252880	216	33.57	61	182	150	244	1.9e-14	35.4	COG3649	CRISPR/Cas system type I-B associated protein Csh2, Cas7 group, RAMP superfamily	283
2918252882	303	86.62	49	293	29	274	2.8e-21	71	COG2801	Transposase InsO and inactivated derivatives	232
2918252883	88	60.68	1	79	1	71	1.0e-13	46.5	COG2963	Transposase and inactivated derivatives	116
2918252884	235	93.28	1	235	17	266	2.7e-61	202.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918252885	409	47.78	204	405	12	194	1.0e-12	25	COG0477	MFS family permease	338
2918252885	409	50.91	10	225	17	211	1.0e-12	21.8	COG0477	MFS family permease	338
2918252886	259	87.88	116	255	11	126	8.0e-21	68.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918252887	704	85.57	29	629	7	593	2.2e-72	238.8	COG1289	Uncharacterized membrane protein YccC	674
2918252888	71	10	1	64	47	75	3.8e-03	11.5	COG1398	Fatty-acid desaturase	289
2918252889	306	91.76	4	302	16	338	1.7e-75	245.5	COG1566	Multidrug resistance efflux pump	352
2918252891	467	50.65	271	465	2	195	3.4e-41	32.7	COG0477	MFS family permease	338
2918252891	467	82.77	38	329	2	318	3.4e-41	112.9	COG0477	MFS family permease	338
2918252892	310	97.32	1	305	4	294	3.8e-59	194.5	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918252893	338	99.1	1	329	1	331	1.9e-97	321.2	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918252896	383	94.67	17	383	18	372	4.8e-46	152	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2918252897	405	96.9	12	392	12	386	2.3e-104	343.9	COG3146	Predicted N-acyltransferase	387
2918252898	306	98.67	5	300	2	298	1.2e-55	184.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918252899	732	99.33	13	730	4	743	0.0e+00	669.6	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918252900	316	98.95	1	316	1	283	4.9e-100	329.3	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2918252901	223	96.79	55	223	3	153	1.1e-67	221.2	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918252902	238	89.38	8	235	11	212	8.8e-21	68.7	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
2918252903	140	93.94	4	121	2	125	5.6e-30	98.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918252904	775	99.18	20	774	3	727	0.0e+00	756.8	COG2217	Cation transport ATPase	713
2918252905	315	95.68	15	314	9	296	1.4e-43	143.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918252906	158	99.37	1	155	1	157	1.8e-37	123.5	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918252907	355	98.67	53	355	2	298	1.1e-35	118.1	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918252908	376	97.94	5	374	5	384	4.1e-81	267.7	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918252909	465	14.42	7	101	150	211	2.4e-31	35.6	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918252909	465	77.91	97	458	94	428	2.4e-31	72.6	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918252910	96	7.46	10	94	5	77	1.0e-05	18.2	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2918252911	264	91.76	1	258	13	257	3.6e-77	253.8	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918252912	296	92.36	11	294	13	278	9.9e-76	249.3	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918252913	373	97.73	1	359	5	349	1.4e-126	417.1	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918252914	273	99.19	10	256	1	244	1.2e-58	192.6	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918252915	555	66.75	111	545	127	389	9.6e-50	164.6	COG0642	Signal transduction histidine kinase	336
2918252916	423	98.5	3	413	4	398	0.0e+00	490.2	COG3214	Uncharacterized conserved protein YcaQ, contains winged helix DNA-binding domain	400
2918252917	160	96.84	3	157	5	157	7.6e-41	134.3	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918252918	402	98.83	18	368	2	340	3.1e-85	280.9	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918252919	268	91.63	39	268	6	235	1.3e-74	245.5	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918252920	270	97.29	6	263	6	256	2.6e-86	283.9	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918252921	391	97.96	14	360	1	336	5.6e-84	276.7	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918252922	315	94.93	1	313	2	319	7.0e-67	220.7	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918252923	431	99.3	1	431	3	426	0.0e+00	593.7	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
2918252924	356	98.46	17	343	6	325	5.7e-102	336	COG3491	Isopenicillin N synthase and related dioxygenases	322
2918252927	360	91.17	20	287	5	262	5.0e-37	122.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918252928	389	91.69	16	388	30	393	1.1e-114	378.6	COG4597	ABC-type amino acid transport system, permease component	397
2918252929	368	89.91	152	368	22	226	5.8e-60	196.9	COG0765	ABC-type amino acid transport system, permease component	222
2918252930	207	52.59	40	202	91	212	3.9e-17	57.8	COG0671	Membrane-associated phospholipid phosphatase	232
2918252935	220	18.94	11	85	7	56	3.6e-20	46.8	COG1192	Cellulose biosynthesis protein BcsQ	259
2918252935	220	43.56	76	207	122	236	3.6e-20	19.1	COG1192	Cellulose biosynthesis protein BcsQ	259
2918252936	195	12.65	21	168	309	373	1.5e-04	15.1	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2918252937	312	97.67	2	294	1	294	2.9e-61	202.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918252938	440	97.81	23	429	5	362	1.1e-40	133.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918252939	288	97.67	2	288	3	296	1.8e-76	252.2	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918252940	340	96.9	7	321	7	319	7.9e-75	246.7	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918252941	239	98.82	2	239	4	254	1.6e-87	287.1	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918252942	234	99.16	1	234	3	237	4.2e-93	305.5	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918252943	267	95.09	3	263	12	263	3.5e-117	384.7	COG4336	Uncharacterized protein YcsI, UPF0317 family	265
2918252944	259	94.71	16	239	3	217	1.4e-67	221.8	COG2049	Allophanate hydrolase subunit 1	223
2918252945	341	97.15	6	314	2	308	5.8e-96	315.8	COG1984	Allophanate hydrolase subunit 2	314
2918252946	254	99.21	1	253	1	250	1.8e-103	339.9	COG1540	Lactam utilization protein B (function unknown)	252
2918252947	456	95.5	5	453	15	460	3.1e-127	420.1	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2918252952	150	80.49	2	150	22	153	7.3e-35	114.9	COG4765	Uncharacterized protein	164
2918252953	149	26.21	1	149	268	386	3.5e+00	1	COG3846	Type IV secretory pathway, TrbL components	452
2918252954	252	51.97	4	246	43	187	2.1e-19	65	COG0500	SAM-dependent methyltransferase	257
2918252955	163	39.73	1	156	6	152	4.8e-39	129.2	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2918252956	131	88.14	8	131	14	117	7.1e-36	118	COG3761	NADH:ubiquinone oxidoreductase 17.2 kD subunit	118
2918252957	220	96.15	6	217	7	206	1.1e-56	185.9	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918252958	298	90.58	10	298	19	297	3.8e-70	231.1	COG1560	Lauroyl/myristoyl acyltransferase	308
2918252959	340	96.73	1	328	6	330	7.2e-89	292.8	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
2918252960	427	99.52	2	418	2	417	1.9e-127	420	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
2918252962	204	91.24	1	204	7	183	2.4e-76	250.7	COG3644	Uncharacterized protein	194
2918252963	332	97.56	1	329	2	400	5.8e-35	116.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918252964	282	99.59	29	266	1	240	1.3e-70	232.2	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
2918252965	310	97.02	15	310	3	295	3.8e-54	178.4	COG1597	Diacylglycerol kinase family enzyme	301
2918252966	451	99.12	9	451	4	455	3.0e-123	406.6	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2918252967	158	91.67	7	143	4	135	4.2e-20	67.2	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918252968	508	99.59	1	501	1	481	0.0e+00	699.1	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
2918252969	218	95.43	1	216	10	218	5.7e-73	239.5	COG3897	Predicted nicotinamide N-methyase	218
2918252971	307	96.9	20	307	7	287	4.8e-90	296.2	COG0382	4-hydroxybenzoate polyprenyltransferase	289
2918252972	133	92.48	5	133	7	129	1.2e-17	58.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918252973	262	98.37	4	242	4	245	1.1e-56	186.6	COG1385	16S rRNA U1498 N3-methylase RsmE	246
2918252974	454	99.12	1	454	5	456	0.0e+00	641.5	COG3572	Gamma-glutamylcysteine synthetase	456
2918252976	1001	26.67	714	865	131	246	2.1e-27	57	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918252976	1001	31.72	2	200	123	260	2.1e-27	31.2	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918252976	1001	67.2	884	1001	15	98	2.8e-11	37.6	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918252976	1001	82.49	206	585	67	391	2.5e-82	272.3	COG0642	Signal transduction histidine kinase	336
2918252977	283	96.93	1	269	1	253	9.7e-80	262.1	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2918252978	359	99.37	22	351	1	316	6.8e-105	345.9	COG2025	Electron transfer flavoprotein, alpha subunit	313
2918252979	433	99.51	2	432	2	406	1.2e-104	345.3	COG0644	Dehydrogenase (flavoprotein)	396
2918252980	97	95.96	1	97	5	99	2.6e-40	131.5	COG2440	Ferredoxin-like protein FixX	99
2918252981	136	54.98	13	134	2	117	8.7e-19	62.6	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918252983	111	39.08	9	105	55	122	1.7e-03	13	COG0225	Peptide methionine sulfoxide reductase MsrA	174
2918252984	285	89.8	10	209	6	181	3.4e-79	259.1	COG1045	Serine acetyltransferase	194
2918252985	375	89.83	5	374	3	373	3.1e-113	373.5	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918252986	404	99.22	6	390	3	385	0.0e+00	492.6	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
2918252987	314	84.95	227	308	5	83	1.1e-19	61.7	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
2918252987	314	88.89	135	197	3	58	3.5e-08	28.5	COG2906	Bacterioferritin-associated ferredoxin	63
2918252987	314	93.38	1	130	6	146	9.0e-44	143.1	COG0822	NifU homolog involved in Fe-S cluster formation	150
2918252988	128	96.36	1	107	4	109	8.0e-38	123.3	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2918252990	97	83.56	19	96	4	64	1.9e-10	35.1	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2918252991	66	92.96	1	66	5	70	2.3e-22	73.6	COG5420	Uncharacterized protein	71
2918252994	464	91.27	3	447	23	440	6.6e-88	289.8	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2918252995	469	97.82	2	462	7	454	1.0e-113	374.9	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2918252997	519	98.03	39	518	6	454	1.6e-122	403.8	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2918252998	479	96.29	24	477	2	442	0.0e+00	479.3	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2918252999	300	99.28	6	284	2	277	0.0e+00	436	COG1348	Nitrogenase subunit NifH, an ATPase	278
2918253002	297	21.97	203	288	236	304	2.5e-49	57	COG1397	ADP-ribosylglycohydrolase	314
2918253002	297	62.1	1	206	5	199	2.5e-49	104.9	COG1397	ADP-ribosylglycohydrolase	314
2918253003	142	96.58	2	115	3	115	8.5e-10	33.4	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2918253004	362	98.93	1	361	3	372	4.0e-115	379.9	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
2918253005	212	86.88	2	203	23	214	1.1e-81	267.4	COG2360	Leu/Phe-tRNA-protein transferase	221
2918253006	253	79.6	1	216	44	242	3.5e-52	172	COG3719	Ribonuclease I	249
2918253007	299	93.4	4	297	19	287	1.0e-64	213.3	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
2918253008	254	90.43	6	244	4	192	6.3e-33	108.8	COG0406	Broad specificity phosphatase PhoE	208
2918253009	365	98.62	2	365	4	361	1.0e-107	355.2	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918253010	192	94.03	126	192	3	65	1.4e-56	96.7	COG1278	Cold shock protein, CspA family	67
2918253010	192	95.52	19	85	3	66	1.4e-56	85.1	COG1278	Cold shock protein, CspA family	67
2918253012	242	92.2	23	224	4	204	3.3e-34	112.8	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918253013	225	87.37	19	212	9	181	1.6e-41	136.6	COG4725	N6-adenosine-specific RNA methylase IME4	198
2918253014	578	61.56	26	283	80	276	2.1e-88	42.8	COG0616	Periplasmic serine protease, ClpP class	317
2918253014	578	67.81	267	563	60	276	2.1e-88	249.6	COG0616	Periplasmic serine protease, ClpP class	317
2918253015	190	90.86	9	183	17	185	1.1e-32	108.3	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918253016	372	89.47	18	286	6	124	2.8e-23	76.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918253019	1081	94.39	568	956	1	387	0.0e+00	264.6	COG0458	Carbamoylphosphate synthase large subunit	400
2918253019	1081	98.29	13	427	1	403	0.0e+00	696.9	COG0458	Carbamoylphosphate synthase large subunit	400
2918253020	152	99.34	1	152	1	151	6.7e-60	196.2	COG0782	Transcription elongation factor, GreA/GreB family	151
2918253021	205	98.95	7	198	2	189	1.6e-90	296.7	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
2918253022	161	89.03	1	152	14	151	2.2e-52	171.7	COG3043	Nitrate reductase cytochrome c-type subunit	155
2918253023	833	99.88	2	831	1	809	0.0e+00	731.4	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918253024	83	79.79	1	83	6	80	8.3e-15	49.4	COG3062	Cytoplasmic chaperone NapD for the signal peptide of periplasmic nitrate reductase NapAB	94
2918253025	33	48.39	1	33	24	53	1.5e-13	45.3	COG4459	Periplasmic nitrate reductase system, NapE component	62
2918253026	243	95.13	11	240	9	223	5.9e-50	164.7	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
2918253027	693	80.2	261	678	71	386	5.7e-55	182.1	COG0642	Signal transduction histidine kinase	336
2918253028	204	94.83	3	179	5	169	1.9e-42	139.8	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2918253029	165	93.6	1	164	2	162	2.1e-43	143	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
2918253030	122	81.06	1	120	15	121	1.2e-10	36	COG5649	Uncharacterized protein	132
2918253031	677	53.86	43	674	427	928	0.0e+00	747.7	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2918253033	213	93.1	43	213	6	167	5.8e-69	226.1	COG0225	Peptide methionine sulfoxide reductase MsrA	174
2918253035	270	91.63	9	269	17	257	2.5e-55	182.2	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2918253036	192	98.14	1	164	1	158	7.4e-43	140.6	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
2918253038	622	98.06	1	611	13	620	0.0e+00	789.4	COG4547	Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib...	620
2918253040	334	87.27	26	326	3	290	9.4e-52	170.8	COG0714	MoxR-like ATPase	329
2918253042	90	90	1	90	6	86	8.6e-32	104.1	COG0271	Stress-induced morphogen (activity unknown)	90
2918253043	162	66.67	12	113	16	83	9.2e-15	48.6	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918253045	152	92.02	3	123	13	162	2.2e-22	74.7	COG0517	CBS domain	117
2918253046	161	80.25	17	155	13	138	1.1e-05	20	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2918253048	374	98.61	5	373	3	357	2.0e-123	406.9	COG0337	3-dehydroquinate synthetase	360
2918253049	232	97.09	23	193	3	169	9.3e-53	173.2	COG0703	Shikimate kinase	172
2918253052	338	97.67	16	328	8	300	1.3e-103	341	COG4974	Site-specific recombinase XerD	300
2918253053	534	96.18	3	533	20	573	0.0e+00	553.6	COG2225	Malate synthase	545
2918253054	306	95.35	13	305	10	296	2.7e-29	97	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918253055	248	65.95	1	241	13	196	1.0e-11	40.3	COG0500	SAM-dependent methyltransferase	257
2918253056	321	98.74	4	319	2	314	0.0e+00	450.9	COG0825	Acetyl-CoA carboxylase alpha subunit	317
2918253058	311	40.58	124	270	161	287	2.1e-31	41.4	COG1216	Glycosyltransferase, GT2 family	305
2918253058	311	43.13	1	137	3	137	2.1e-31	62.2	COG1216	Glycosyltransferase, GT2 family	305
2918253061	385	43.77	13	365	217	395	1.2e-18	61.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918253062	404	67.73	8	376	106	382	9.0e-28	92.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918253063	418	72.37	20	417	109	404	5.8e-20	66.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918253064	322	98.44	1	309	3	318	1.1e-75	249.8	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918253065	333	98.44	1	322	3	318	2.9e-71	235.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918253066	451	91.97	4	432	10	410	5.2e-87	286.7	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
2918253067	481	97.72	1	468	5	475	4.9e-60	198	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2918253068	756	77.62	508	756	30	251	1.6e-40	132.6	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918253068	756	96.34	26	504	16	463	2.0e-105	347.6	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918253069	198	95.6	18	197	9	182	6.5e-80	261.9	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918253070	439	86.29	24	437	48	387	3.0e-25	84.2	COG0642	Signal transduction histidine kinase	336
2918253071	278	74.84	22	276	5	233	1.6e-71	235.8	COG1131	ABC-type multidrug transport system, ATPase component	293
2918253072	278	64.85	19	269	88	277	5.3e-06	20.4	COG0842	ABC-type multidrug transport system, permease component	286
2918253073	373	39.64	203	352	195	328	3.1e-83	146.1	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
2918253073	373	60.95	1	208	5	210	3.1e-83	126.8	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
2918253074	256	96.37	12	256	3	241	2.0e-76	251.6	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
2918253077	1265	28.17	186	367	35	145	3.9e-74	5.1	COG0642	Signal transduction histidine kinase	336
2918253077	1265	65.23	392	716	127	383	3.9e-74	245.4	COG0642	Signal transduction histidine kinase	336
2918253077	1265	91.73	896	1206	6	127	2.3e-66	119.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918253077	1265	93.23	733	866	5	128	2.3e-66	92.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918253078	305	68.97	1	301	132	431	1.3e-110	364.7	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918253079	350	92.38	1	350	29	404	1.7e-60	195.8	COG0303	Molybdopterin biosynthesis enzyme	404
2918253080	656	87	444	655	15	208	2.3e-47	155.3	COG1910	Periplasmic molybdate-binding protein/domain	223
2918253080	656	98.53	17	436	3	403	4.3e-118	388.7	COG0303	Molybdopterin biosynthesis enzyme	404
2918253082	334	99.02	4	320	2	305	1.5e-126	416.3	COG0492	Thioredoxin reductase	305
2918253084	202	85.4	50	186	4	120	2.8e-26	86.4	COG1695	DNA-binding transcriptional regulator, PadR family	138
2918253085	97	91.67	1	96	1	88	1.7e-30	100	COG3553	Uncharacterized protein	96
2918253088	326	99.09	5	319	2	327	1.8e-79	261.8	COG3660	Mitochondrial fission protein ELM1	329
2918253089	164	81.65	1	135	24	152	1.3e-31	104.5	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918253090	428	84.77	230	425	10	176	2.4e-74	58.9	COG2059	Chromate transport protein ChrA	195
2918253090	428	86.8	4	211	10	180	2.4e-74	192.1	COG2059	Chromate transport protein ChrA	195
2918253091	302	97.05	34	300	6	235	1.2e-39	130.7	COG0412	Dienelactone hydrolase	236
2918253094	84	97.26	1	73	1	71	1.2e-32	106.5	COG3655	DNA-binding transcriptional regulator, XRE family	73
2918253097	496	88.2	27	478	34	429	1.5e-91	294.6	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
2918253098	187	95.21	32	168	5	143	9.9e-24	78.4	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2918253099	379	70.51	31	266	51	258	1.4e-33	110.9	COG3016	Uncharacterized iron-regulated protein	295
2918253100	245	98.51	1	243	4	267	6.8e-62	204.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918253102	1076	92.65	12	1060	3	1074	0.0e+00	1000.2	COG0587	DNA polymerase III, alpha subunit	1139
2918253103	524	98.4	69	474	3	370	1.8e-31	103.8	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918253105	164	81.59	1	164	36	199	1.7e-17	58	COG2370	Hydrogenase/urease accessory protein HupE	201
2918253106	354	94.1	4	333	17	319	6.8e-78	256.3	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
2918253107	214	98.14	5	210	2	212	3.8e-38	126.1	COG0625	Glutathione S-transferase	211
2918253108	458	91.79	21	458	39	485	1.1e-130	431.7	COG0260	Leucyl aminopeptidase	485
2918253109	340	96.18	2	339	11	337	4.3e-99	326.6	COG1536	Flagellar motor switch protein FliG	339
2918253111	158	62.41	4	140	17	99	7.4e-16	53	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918253112	308	86.81	11	308	44	326	1.1e-77	255.6	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918253113	194	67.89	1	185	65	231	1.1e-63	209.3	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2918253114	543	99.44	2	534	3	533	0.0e+00	860.1	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
2918253115	362	99.12	1	340	3	340	0.0e+00	583.8	COG4239	ABC-type microcin C transport system, permease component YejE	341
2918253116	370	99.73	1	369	1	363	0.0e+00	612.5	COG4174	ABC-type microcin C transport system, permease component YejB	364
2918253117	619	98.61	9	608	7	572	0.0e+00	497.3	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2918253118	617	98.08	1	609	5	567	1.6e-126	417.9	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2918253120	260	97.3	7	259	7	258	9.6e-65	213.1	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2918253121	302	97.89	13	300	1	278	1.2e-73	242.9	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
2918253122	288	98.21	3	279	3	277	3.8e-80	263.8	COG0077	Prephenate dehydratase	279
2918253123	261	97.17	10	255	4	243	3.6e-90	296	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
2918253124	180	81.62	46	176	25	135	7.2e-42	137.2	COG3474	Cytochrome c2	135
2918253125	197	97.98	1	197	4	197	4.0e-74	243	COG0353	Recombinational DNA repair protein RecR	198
2918253126	107	96.19	1	104	4	104	2.6e-39	128.3	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
2918253127	635	64.96	19	605	2	381	0.0e+00	503.9	COG2812	DNA polymerase III, gamma/tau subunits	515
2918253129	397	98.49	1	397	4	395	0.0e+00	491.4	COG0126	3-phosphoglycerate kinase	395
2918253130	535	94.87	6	491	2	426	3.0e-69	228.7	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
2918253131	207	20.83	1	71	2	56	7.7e-26	50.9	COG1192	Cellulose biosynthesis protein BcsQ	259
2918253131	207	45.08	64	205	127	245	7.7e-26	33.8	COG1192	Cellulose biosynthesis protein BcsQ	259
2918253133	482	88.32	14	472	44	391	8.1e-44	145.4	COG0642	Signal transduction histidine kinase	336
2918253135	482	98.73	4	482	4	469	0.0e+00	574.7	COG2870	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase	467
2918253136	52	97.73	3	46	2	44	1.1e-16	55.1	COG5510	Predicted small secreted protein	44
2918253137	195	95	1	195	8	197	2.5e-18	60.8	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
2918253138	466	99.56	2	456	3	455	0.0e+00	557.6	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918253139	944	95.94	580	912	7	313	1.6e-84	278.7	COG1754	Uncharacterized C-terminal domain of topoisomerase IA	298
2918253139	944	97.39	4	586	2	561	0.0e+00	677.6	COG0550	DNA topoisomerase IA	570
2918253140	373	99.16	8	373	2	357	6.6e-114	375.3	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
2918253141	276	98.49	15	273	5	265	2.5e-65	215.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918253142	218	87.28	12	218	18	216	7.8e-39	128.5	COG0705	Membrane associated serine protease, rhomboid family	228
2918253143	294	93.16	3	251	17	261	8.3e-83	272.6	COG0005	Purine nucleoside phosphorylase	262
2918253144	155	92.9	1	155	7	150	1.8e-41	136.3	COG2153	Predicted N-acyltransferase, GNAT family	155
2918253145	161	48.44	8	157	3	142	2.5e-13	44.5	COG5483	Uncharacterized conserved protein, DUF488 family	289
2918253148	170	97.6	1	166	1	163	1.8e-60	198.3	COG3685	Ferritin-like metal-binding protein YciE	167
2918253151	147	89.86	3	146	10	142	5.2e-62	202.8	COG4957	Predicted transcriptional regulator	148
2918253152	145	92.72	4	145	3	142	4.3e-57	186.8	COG0698	Ribose 5-phosphate isomerase RpiB	151
2918253153	433	98.8	11	431	5	414	0.0e+00	634.8	COG0112	Glycine/serine hydroxymethyltransferase	413
2918253154	154	96.15	1	153	1	150	8.5e-66	215.4	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
2918253155	369	97.26	3	148	4	145	1.8e-56	184	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
2918253155	369	98.64	149	369	2	218	2.9e-68	224.1	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
2918253156	195	94.63	1	195	1	194	2.3e-72	237.1	COG0307	Riboflavin synthase alpha chain	204
2918253157	379	85.2	210	376	7	173	2.7e-33	109.1	COG0807	GTP cyclohydrolase II	193
2918253157	379	97.54	7	210	5	202	4.2e-83	272.3	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
2918253158	154	92.76	1	148	11	151	6.1e-38	124.7	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
2918253159	188	94.12	18	175	8	151	1.8e-28	94	COG0781	Transcription termination factor NusB	151
2918253160	333	99.38	7	333	3	320	7.8e-87	285.9	COG0611	Thiamine monophosphate kinase	317
2918253162	674	95.59	1	674	30	701	0.0e+00	978.2	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
2918253163	161	97.33	3	148	5	150	6.0e-29	95.6	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
2918253164	197	88.33	13	194	17	175	7.2e-40	131.5	COG5452	Uncharacterized protein	180
2918253165	193	90.5	15	192	17	178	8.4e-09	26.5	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
2918253166	62	98.25	1	57	1	56	1.4e-28	93.7	COG0333	Ribosomal protein L32	57
2918253167	350	98.23	4	341	2	334	3.3e-123	405.7	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
2918253168	323	99.08	2	323	3	325	0.0e+00	444.5	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2918253169	115	96.81	5	98	2	92	2.4e-31	102.5	COG0776	Bacterial nucleoid DNA-binding protein	94
2918253170	149	58.33	8	146	2	78	8.9e-19	62.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918253173	143	87.67	1	143	13	140	1.6e-15	51.7	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2918253174	266	64.65	9	236	57	270	2.6e-45	146	COG0790	TPR repeat	292
2918253176	694	97.47	283	687	8	392	1.4e-22	74.7	COG2814	Predicted arabinose efflux permease, MFS family	394
2918253177	350	79.5	47	343	50	305	4.1e-34	112.3	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
2918253178	260	67.28	18	204	40	148	4.7e-05	18.7	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918253180	480	69.05	190	270	13	70	4.7e-01	13.8	COG2770	HAMP domain	83
2918253181	716	67.39	429	692	118	365	4.2e-70	229.7	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2918253182	112	88.03	1	111	3	105	1.1e-20	68.3	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918253183	131	93.98	1	130	5	129	5.0e-25	82.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918253184	409	56.85	156	340	86	197	5.1e-33	109.8	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918253185	226	92.82	6	202	11	204	2.1e-28	94.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918253186	405	92.56	2	382	17	377	6.0e-60	198	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918253187	1038	99.9	2	1013	1	1013	0.0e+00	1146.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2918253189	170	84.54	1	169	23	186	1.4e-21	71.1	COG1525	Endonuclease YncB, thermonuclease family	192
2918253190	813	42.11	66	134	35	74	4.2e-03	10.8	COG2088	DNA-binding protein SpoVG, cell septation regulator	95
2918253191	131	59.54	2	111	40	117	2.3e-14	48.1	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918253192	98	88.89	2	96	7	94	2.9e-04	15.8	COG3668	Plasmid stabilization system protein ParE	98
2918253194	1167	95.1	713	925	6	199	4.6e-30	98.9	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
2918253194	1167	99.07	16	698	2	639	0.0e+00	627.2	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
2918253195	324	94.74	5	268	6	131	4.5e-24	79.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918253196	241	64.88	20	236	23	216	1.3e-03	11.3	COG1230	Co/Zn/Cd efflux system component	296
2918253197	753	93.79	29	540	24	461	2.6e-107	354.3	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2918253197	753	94.76	553	742	2	182	2.1e-55	181.4	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
2918253198	82	91.76	1	81	7	84	4.1e-38	123.8	COG3750	Uncharacterized conserved protein, UPF0335 family	85
2918253199	155	38.84	2	155	1	141	3.7e-45	149.5	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2918253200	98	78.65	6	89	2	71	1.1e-16	55.7	COG1343	CRISPR/Cas system-associated endoribonuclease Cas2	89
2918253201	567	90.86	19	212	17	195	9.0e-18	59.3	COG1468	CRISPR/Cas system-associated exonuclease Cas4, RecB family	190
2918253201	567	97.26	230	563	3	321	1.9e-77	255.1	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
2918253202	910	65.43	623	822	1	176	2.1e-04	15.7	COG2887	RecB family exonuclease	269
2918253203	1064	4.86	915	1054	1075	1130	1.0e-81	6.3	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2918253203	1064	5.12	7	80	21	79	1.0e-81	59.2	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2918253203	1064	62.41	78	805	120	838	1.0e-81	194.5	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2918253208	607	9.34	69	124	73	109	3.8e-20	1.3	COG3864	Predicted metal-dependent peptidase	396
2918253208	607	25.25	234	355	39	138	3.8e-20	30.2	COG3864	Predicted metal-dependent peptidase	396
2918253208	607	42.42	399	592	199	366	3.8e-20	31.2	COG3864	Predicted metal-dependent peptidase	396
2918253209	361	64.24	11	274	37	248	2.2e-20	67.4	COG0714	MoxR-like ATPase	329
2918253210	283	91.16	20	262	1	227	1.6e-60	199.5	COG3541	Predicted nucleotidyltransferase	248
2918253212	328	94.57	1	323	3	298	1.2e-32	108.3	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2918253213	1145	98.68	1	1141	1	971	1.1e-66	215	COG4717	Uncharacterized protein YhaN	984
2918253214	420	73.51	4	327	3	299	4.5e-39	126.5	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
2918253215	1964	44.19	1645	1754	69	125	1.3e-05	18.9	COG2852	Very-short-patch-repair endonuclease	129
2918253217	536	52.68	291	534	192	407	7.0e-48	77.8	COG3464	Transposase	402
2918253217	536	54.39	14	260	28	250	7.0e-48	80.9	COG3464	Transposase	402
2918253219	391	100	1	391	1	353	1.1e-114	377.5	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918253220	552	97.89	12	549	5	560	6.1e-107	352.9	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918253221	381	97.74	1	381	5	394	4.9e-123	405.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918253222	482	99.16	8	482	1	475	0.0e+00	527.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918253223	378	100	1	375	1	379	5.7e-116	382.2	COG1454	Alcohol dehydrogenase, class IV	377
2918253224	522	96.78	1	522	3	513	0.0e+00	529.3	COG4670	Acyl CoA:acetate/3-ketoacid CoA transferase	527
2918253225	151	79.25	15	151	26	151	5.0e-30	98.5	COG2030	Acyl dehydratase	159
2918253227	302	97.34	1	296	1	293	2.3e-69	229.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918253228	404	96.45	15	384	10	362	7.0e-42	138.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918253229	199	60.68	1	186	127	322	3.6e-51	169	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918253230	124	42.91	1	122	3	111	1.2e-41	137.4	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918253233	204	41.86	67	196	54	107	5.1e-07	24	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2918253234	327	57.35	19	314	50	209	2.8e-03	12.7	COG0500	SAM-dependent methyltransferase	257
2918253235	218	97.3	1	217	7	222	9.0e-84	275.1	COG2011	ABC-type methionine transport system, permease component	222
2918253236	380	93.24	39	372	2	318	2.9e-112	369.9	COG1135	ABC-type methionine transport system, ATPase component	339
2918253237	273	97.04	5	273	9	270	2.7e-83	273.8	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
2918253238	183	80.29	33	174	24	133	9.1e-09	29.9	COG1765	Uncharacterized OsmC-related protein	137
2918253239	413	98.24	8	402	7	396	0.0e+00	462.5	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2918253240	475	93.39	7	468	30	467	2.9e-101	334.3	COG0277	FAD/FMN-containing dehydrogenase	459
2918253241	262	94.81	1	262	15	270	1.2e-86	284.9	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
2918253242	385	96.21	3	381	13	393	2.1e-88	291.5	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918253244	130	23.62	4	105	263	343	6.3e-18	59.6	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918253246	334	96.72	1	324	10	333	6.7e-52	171.5	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918253247	277	94.57	2	276	12	255	1.6e-83	274.5	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918253248	282	97.61	20	272	4	248	6.2e-99	325.1	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918253249	457	98.5	5	456	4	463	0.0e+00	550.8	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918253250	608	99.17	12	606	5	603	0.0e+00	613.2	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2918253251	307	97.67	6	301	2	295	6.9e-65	214.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918253252	267	96.86	1	217	5	189	1.6e-69	228.3	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
2918253253	500	84.77	60	494	56	389	3.3e-54	179.8	COG0642	Signal transduction histidine kinase	336
2918253254	149	89.47	4	139	8	126	2.3e-20	67.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918253255	346	93.23	1	130	5	128	5.0e-20	65.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918253255	346	96.05	127	346	5	223	1.1e-52	173	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918253256	1337	26.07	1026	1171	363	508	3.0e-70	49.7	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918253256	1337	35.36	692	1017	308	505	3.0e-70	43.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918253256	1337	35.89	1114	1337	345	545	3.0e-70	47.7	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918253256	1337	38.93	4	584	264	481	3.0e-70	42.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918253256	1337	39.46	483	738	293	513	3.0e-70	78	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918253258	360	70.71	87	356	36	245	3.2e-20	65.2	COG1533	DNA repair photolyase	297
2918253259	165	92.4	1	165	9	166	2.1e-27	91.1	COG3652	Predicted outer membrane protein	170
2918253260	364	97.01	1	246	3	262	1.2e-47	157.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918253261	530	77.81	28	316	6	303	6.0e-13	44	COG0477	MFS family permease	338
2918253262	397	94.03	33	391	14	344	7.2e-100	328.5	COG1566	Multidrug resistance efflux pump	352
2918253263	410	35.98	3	94	36	94	9.9e-42	13.4	COG2010	Cytochrome c, mono- and diheme variants	150
2918253263	410	64.63	283	410	57	162	9.9e-42	53.9	COG2010	Cytochrome c, mono- and diheme variants	150
2918253263	410	98.78	109	282	1	162	9.9e-42	78.4	COG2010	Cytochrome c, mono- and diheme variants	150
2918253264	590	97.54	1	588	6	559	2.1e-72	239.4	COG2303	Choline dehydrogenase or related flavoprotein	542
2918253266	191	15.79	114	189	105	131	5.5e-08	9.3	COG5592	Hemerythrin superfamily protein	171
2918253266	191	30.41	47	125	78	129	5.5e-08	17	COG5592	Hemerythrin superfamily protein	171
2918253270	1139	93.16	19	1131	23	1084	0.0e+00	851.1	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
2918253271	157	92.81	1	157	7	161	3.1e-63	207.4	COG3685	Ferritin-like metal-binding protein YciE	167
2918253274	393	81.57	13	384	4	335	5.8e-32	105.5	COG0644	Dehydrogenase (flavoprotein)	396
2918253278	499	56.71	3	117	66	158	6.1e-17	55.8	COG2010	Cytochrome c, mono- and diheme variants	150
2918253279	172	78.48	12	169	5	128	2.6e-20	67.8	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918253280	149	73.42	1	131	4	119	1.8e-18	61.8	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918253281	177	91.14	13	173	6	149	5.6e-18	60.1	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918253282	152	77.85	1	140	7	129	1.1e-19	65.8	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918253284	114	57.32	2	106	30	123	3.3e-11	38.3	COG2010	Cytochrome c, mono- and diheme variants	150
2918253285	263	99.18	1	247	2	243	9.0e-95	311.7	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2918253286	108	76.56	2	108	30	127	2.6e-22	74.2	COG3794	Plastocyanin	128
2918253287	551	84.74	6	192	22	182	1.7e-79	261	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
2918253288	546	68.9	3	132	43	155	3.5e-13	43.6	COG2010	Cytochrome c, mono- and diheme variants	150
2918253289	236	88.99	7	219	13	206	3.3e-27	90	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918253290	257	83.49	39	242	27	208	1.6e-25	84.5	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918253291	395	94.69	12	382	18	356	2.6e-76	251.7	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2918253292	248	99.57	1	230	1	229	7.8e-91	298.6	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
2918253293	109	42.11	10	101	16	71	1.8e-06	22.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918253295	766	97.59	13	720	10	696	0.0e+00	896.9	COG1523	Pullulanase/glycogen debranching enzyme	697
2918253296	719	66.49	582	719	7	135	1.0e-07	26.5	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
2918253296	719	80.71	152	569	74	391	7.5e-51	168.3	COG0642	Signal transduction histidine kinase	336
2918253297	430	25.5	352	430	124	187	1.2e-70	54.3	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918253297	430	27.49	263	355	110	178	1.2e-70	49.3	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918253297	430	35.46	135	234	132	220	1.2e-70	73.7	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918253297	430	49.4	2	139	63	186	1.2e-70	70.6	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918253299	525	72.86	15	518	106	403	4.5e-10	34	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918253300	357	98.85	9	350	4	346	3.5e-120	395.6	COG2089	Sialic acid synthase SpsE, contains C-terminal SAF domain	347
2918253301	257	98.76	5	256	3	240	4.6e-64	210.4	COG1861	Spore coat polysaccharide biosynthesis protein SpsF, cytidylyltransferase family	241
2918253302	77	76.54	3	74	14	75	7.3e-08	27.2	COG0236	Acyl carrier protein	80
2918253303	278	98.31	3	271	5	294	7.7e-39	128.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918253304	82	79.01	1	79	12	75	4.2e-06	21.5	COG0236	Acyl carrier protein	80
2918253305	393	62.68	63	390	189	534	1.0e-31	104	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918253306	259	98.88	12	258	3	267	7.1e-63	207.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918253307	360	97.85	7	325	5	323	3.1e-79	260.9	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2918253308	621	70.1	316	621	116	387	5.2e-21	32.1	COG1344	Flagellin and related hook-associated protein FlgL	360
2918253308	621	78.61	4	337	12	316	5.2e-21	46.5	COG1344	Flagellin and related hook-associated protein FlgL	360
2918253309	135	81.08	1	132	3	122	1.1e-24	81.6	COG5443	Flagellar biosynthesis regulator FlbT	148
2918253310	1959	47.55	959	1136	71	245	1.9e-93	46.7	COG0457	Tetratricopeptide (TPR) repeat	291
2918253310	1959	51.9	681	961	157	347	1.9e-93	34.4	COG0457	Tetratricopeptide (TPR) repeat	291
2918253310	1959	59.24	157	342	127	344	1.9e-93	55.3	COG0457	Tetratricopeptide (TPR) repeat	291
2918253310	1959	60.6	302	522	96	318	1.9e-93	62.7	COG0457	Tetratricopeptide (TPR) repeat	291
2918253310	1959	65.49	2	217	104	344	1.9e-93	61.2	COG0457	Tetratricopeptide (TPR) repeat	291
2918253310	1959	83.42	1383	1713	52	358	1.9e-93	80.4	COG0457	Tetratricopeptide (TPR) repeat	291
2918253311	58	92.98	1	58	1	53	4.7e-09	31.1	COG5570	Uncharacterized protein	57
2918253312	761	91.83	145	760	43	615	6.3e-90	292.4	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918253313	1168	47.55	171	340	184	358	1.6e-60	71.6	COG0457	Tetratricopeptide (TPR) repeat	291
2918253313	1168	69.29	1	219	102	356	1.6e-60	77.5	COG0457	Tetratricopeptide (TPR) repeat	291
2918253313	1168	73.1	519	900	91	359	1.6e-60	71.8	COG0457	Tetratricopeptide (TPR) repeat	291
2918253314	426	97.21	130	425	8	286	3.8e-66	218.3	COG4976	Predicted methyltransferase, contains TPR repeat	287
2918253315	511	81.79	4	329	59	359	1.0e-21	66.4	COG0457	Tetratricopeptide (TPR) repeat	291
2918253318	135	94.2	1	134	6	135	1.4e-20	66.1	COG1558	Flagellar basal body rod protein FlgC	137
2918253319	278	95.98	24	277	8	246	2.6e-56	185.8	COG0368	Cobalamin synthase	246
2918253320	199	89	3	193	4	189	1.2e-30	101.2	COG0406	Broad specificity phosphatase PhoE	208
2918253321	171	90.34	8	150	4	134	6.9e-40	130.7	COG3871	General stress protein 26 (function unknown)	145
2918253322	904	16.35	149	272	63	164	1.6e-105	10.4	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918253322	904	23.08	4	162	36	179	1.6e-105	6.9	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918253322	904	87.66	336	898	75	621	1.6e-105	327.8	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918253323	342	96.86	11	342	2	340	2.9e-111	366.5	COG2038	NaMN:DMB phosphoribosyltransferase	347
2918253324	281	94.12	6	281	5	260	2.5e-51	167	COG0631	Serine/threonine protein phosphatase PrpC	262
2918253326	549	96.32	17	524	3	500	3.6e-104	344.5	COG0366	Glycosidase	505
2918253327	682	22.42	5	97	3	89	5.3e-18	22.5	COG1344	Flagellin and related hook-associated protein FlgL	360
2918253327	682	75.26	202	682	94	385	5.3e-18	46.7	COG1344	Flagellin and related hook-associated protein FlgL	360
2918253328	469	23.3	296	468	447	583	2.7e-63	57.7	COG1256	Flagellar hook-associated protein FlgK	552
2918253328	469	51.87	2	370	2	306	2.7e-63	155.7	COG1256	Flagellar hook-associated protein FlgK	552
2918253329	789	99.79	3	789	2	472	2.1e-76	245.5	COG1749	Flagellar hook protein FlgE	423
2918253330	723	40.1	268	717	223	386	3.6e-04	14.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918253330	723	56.25	1	281	139	345	1.4e-17	58.8	COG0457	Tetratricopeptide (TPR) repeat	291
2918253331	499	63.59	3	262	112	345	9.2e-14	46.4	COG0457	Tetratricopeptide (TPR) repeat	291
2918253332	110	93.04	3	108	2	108	9.7e-17	54.5	COG5447	Uncharacterized protein	115
2918253333	823	84.52	411	823	56	388	1.1e-48	161.7	COG0642	Signal transduction histidine kinase	336
2918253334	508	39.02	8	228	8	213	2.5e-55	91.1	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
2918253334	508	42.05	255	498	279	500	2.5e-55	90	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
2918253335	276	93.6	1	228	2	162	4.5e-17	52.8	COG0622	Predicted phosphodiesterase	172
2918253336	404	77.59	10	380	17	338	1.1e-42	141	COG3919	Predicted ATP-dependent carboligase, ATP-grasp superfamily	415
2918253338	235	96.28	1	210	1	207	2.1e-55	182.5	COG0625	Glutathione S-transferase	211
2918253339	143	85.11	2	135	15	134	5.1e-25	82.4	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918253340	256	95.85	1	253	11	264	6.2e-63	207.3	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918253342	152	50	1	130	2	117	8.5e-16	52.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918253344	926	99.66	7	925	3	888	0.0e+00	996	COG3280	Maltooligosyltrehalose synthase	889
2918253345	1882	74.51	106	516	106	447	8.1e-80	263.7	COG3281	Predicted trehalose synthase	438
2918253345	1882	91.47	518	1113	19	597	0.0e+00	530	COG0296	1,4-alpha-glucan branching enzyme	628
2918253345	1882	97.54	1303	1859	9	524	0.0e+00	542.5	COG1640	4-alpha-glucanotransferase	520
2918253349	393	96.13	2	385	1	373	1.3e-67	223.4	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918253351	450	98.87	12	448	3	438	0.0e+00	452.3	COG0621	tRNA A37 methylthiotransferase MiaB	437
2918253352	159	88.72	24	154	14	131	4.6e-13	43.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918253353	133	71.57	10	115	15	87	1.2e-09	31.7	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918253354	236	98.62	7	223	2	216	1.8e-42	140	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918253355	247	97.12	1	246	4	239	1.4e-77	254.9	COG3482	Uncharacterized protein	237
2918253356	422	95.51	14	418	5	387	7.1e-91	299.3	COG1944	Ribosomal protein S12 methylthiotransferase accessory factor YcaO	398
2918253358	103	66.67	22	103	15	82	4.5e-11	37	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918253359	1019	69.57	524	996	90	345	4.1e-09	27.5	COG0457	Tetratricopeptide (TPR) repeat	291
2918253359	1019	77.05	1	194	50	237	3.8e-29	96.7	COG2114	Adenylate cyclase, class 3	227
2918253360	621	98.27	1	614	10	577	0.0e+00	784.6	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918253361	119	19.59	8	119	177	252	7.8e-01	3.4	COG3064	Membrane protein involved in colicin uptake	387
2918253362	392	83.01	15	388	17	358	7.1e-64	210.6	COG2262	50S ribosomal subunit-associated GTPase HflX	411
2918253363	504	52.29	83	486	87	372	1.6e-03	8.9	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
2918253364	313	87.35	10	302	3	299	8.6e-40	131.6	COG0859	ADP-heptose:LPS heptosyltransferase	334
2918253366	96	86.87	6	96	11	96	1.5e-16	55.2	COG2388	Predicted acetyltransferase, GNAT superfamily	99
2918253367	252	71.58	1	212	83	291	2.5e-53	176.1	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2918253368	289	97.59	2	289	3	285	1.1e-117	386.9	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
2918253369	30	6.94	1	30	5	33	9.7e-10	32.5	COG1004	UDP-glucose 6-dehydrogenase	414
2918253370	33	6.6	1	31	440	470	9.1e-12	39.6	COG1282	NAD/NADP transhydrogenase beta subunit	463
2918253371	95	97.92	1	95	3	96	4.6e-36	117.8	COG5470	Uncharacterized conserved protein, DUF1330 family	96
2918253372	278	96.64	9	274	9	267	1.3e-110	363.6	COG0413	Ketopantoate hydroxymethyltransferase	268
2918253373	67	98.51	1	65	2	67	2.9e-25	82.9	COG0828	Ribosomal protein S21	67
2918253374	175	92.9	1	170	1	157	2.3e-53	174.8	COG0242	Peptide deformylase	168
2918253375	235	78.17	2	197	31	209	6.4e-33	108.8	COG5590	Ubiquinone biosynthesis protein COQ9	229
2918253376	125	90.08	7	121	10	118	4.9e-27	88.8	COG3070	Transcriptional regulator of competence genes, TfoX/Sxy family	121
2918253377	165	100	1	165	1	157	6.4e-55	180	COG3814	Uncharacterized protein	157
2918253379	313	98.55	23	301	4	275	1.7e-71	235.7	COG1351	Thymidylate synthase ThyX	273
2918253380	572	61.86	119	560	237	622	8.7e-88	290	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918253381	591	85.65	391	589	25	215	8.3e-31	102.4	COG1226	Voltage-gated potassium channel Kch	212
2918253381	591	95.5	1	395	6	387	1.4e-96	318.6	COG0475	Kef-type K+ transport system, membrane component KefB	397
2918253382	265	100	1	264	1	263	8.4e-113	370.6	COG1101	ABC-type uncharacterized transport system, ATPase component	263
2918253383	301	99.32	1	296	1	291	4.4e-121	398.4	COG4120	ABC-type uncharacterized transport system, permease component	293
2918253384	326	96.89	2	325	10	321	2.8e-121	399	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
2918253385	125	91.27	1	125	7	121	7.4e-41	133.7	COG5349	Uncharacterized conserved protein, DUF983 family	126
2918253386	389	92.31	39	343	22	285	3.6e-100	329.3	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918253387	400	95.35	63	373	8	294	2.8e-62	205.3	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918253388	291	97.67	1	288	4	297	1.7e-69	229.2	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918253389	495	25.21	394	495	266	357	0.0e+00	36.8	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918253389	495	94.79	1	376	14	359	0.0e+00	415.4	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918253391	163	84.42	1	158	17	146	5.5e-45	147.5	COG2847	Copper(I)-binding protein	151
2918253393	212	7.07	76	136	142	182	1.4e-12	14.9	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2918253393	212	10	124	210	243	300	1.4e-12	12.7	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2918253393	212	10.34	7	82	25	84	1.4e-12	12.5	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2918253397	599	95.44	56	567	11	491	0.0e+00	465.4	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
2918253399	217	90.67	1	214	7	210	1.2e-60	199.8	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
2918253405	122	96.72	2	122	4	121	2.9e-47	154.5	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
2918253406	181	80.93	15	181	9	165	7.8e-85	277.5	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
2918253407	209	97.78	1	178	3	178	1.6e-60	198.9	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
2918253408	415	98.24	22	415	8	398	0.0e+00	604.5	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
2918253409	211	94.58	10	178	8	164	1.6e-63	207.6	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2918253410	429	97.64	1	421	9	422	0.0e+00	632	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2918253411	687	99.04	1	685	1	724	0.0e+00	742.4	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
2918253412	336	99.1	2	333	2	331	0.0e+00	452.5	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
2918253413	162	86.29	2	162	8	158	9.8e-56	182.7	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
2918253414	204	100	1	173	1	168	2.1e-53	175	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
2918253415	102	99	2	102	2	100	5.0e-39	127	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
2918253416	698	96.43	71	693	22	616	0.0e+00	724.2	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2918253417	508	98.59	2	501	2	492	0.0e+00	684	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
2918253418	482	98.53	6	480	7	475	0.0e+00	529.7	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
2918253419	265	98.74	24	261	1	236	6.2e-64	210.6	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
2918253420	257	100	1	254	1	253	2.6e-82	270.9	COG1521	Pantothenate kinase type III	251
2918253421	558	98.35	6	556	7	544	0.0e+00	501.6	COG0595	mRNA degradation ribonuclease J1/J2	555
2918253422	134	97.95	3	133	2	144	1.0e-18	63.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918253423	83	88.76	2	83	3	81	1.5e-20	68.2	COG5454	Predicted secreted protein	89
2918253424	189	96.81	3	169	2	183	4.0e-51	160.6	COG2818	3-methyladenine DNA glycosylase Tag	188
2918253427	437	32.26	247	436	356	525	0.0e+00	173.4	COG0442	Prolyl-tRNA synthetase	500
2918253427	437	42.88	1	244	1	226	0.0e+00	357.1	COG0442	Prolyl-tRNA synthetase	500
2918253430	415	99.76	2	415	2	410	0.0e+00	451.6	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2918253431	245	97.79	1	226	1	221	1.0e-79	261.6	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918253432	285	98.73	61	285	2	235	3.0e-60	198	COG0412	Dienelactone hydrolase	236
2918253433	293	95.68	1	291	9	296	6.3e-46	151.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918253435	1161	98.27	3	1158	3	1139	0.0e+00	1315.6	COG0587	DNA polymerase III, alpha subunit	1139
2918253439	193	83.01	6	181	3	173	4.0e-32	106.3	COG1335	Nicotinamidase-related amidase	205
2918253440	134	96.03	5	129	5	125	2.6e-33	109.3	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
2918253441	347	98.63	13	323	4	291	1.4e-78	258.8	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2918253442	233	93.24	11	228	5	211	1.9e-49	163.2	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918253443	233	87.12	1	233	33	262	9.0e-68	223.1	COG5387	Chaperone required for the assembly of the mitochondrial F1-ATPase	264
2918253444	174	72.73	60	122	3	66	3.1e-07	24.6	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2918253445	305	86.36	5	304	15	280	2.5e-54	179.3	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
2918253446	525	99.4	13	509	4	501	0.0e+00	612	COG3845	ABC-type uncharacterized transport system, ATPase component	501
2918253447	358	96.37	4	357	6	350	8.5e-116	381.1	COG4603	ABC-type uncharacterized transport system, permease component	356
2918253448	310	97.7	2	310	5	301	1.6e-103	340.5	COG1079	ABC-type uncharacterized transport system, permease component	304
2918253449	362	96.32	2	343	10	349	4.2e-88	290.1	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
2918253453	232	89.53	1	220	25	255	4.7e-50	164.5	COG0688	Phosphatidylserine decarboxylase	239
2918253454	311	95.36	28	266	9	234	1.9e-67	222	COG1183	Phosphatidylserine synthase	234
2918253455	124	46.91	28	116	4	79	1.2e-04	16.4	COG0440	Acetolactate synthase, small subunit	163
2918253456	203	35.45	1	184	102	168	2.6e-16	54.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918253457	336	98.31	55	333	2	291	2.9e-43	143.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918253458	317	94.77	22	314	2	273	1.5e-64	212.6	COG2890	Methylase of polypeptide chain release factors	280
2918253459	113	97.44	2	113	2	115	5.9e-31	101.8	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2918253460	414	98.47	8	335	2	322	7.5e-106	348.2	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918253464	637	19.35	19	133	35	100	0.0e+00	7.9	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918253464	637	97.95	259	636	8	341	0.0e+00	429.8	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918253465	638	69.63	2	536	2	416	0.0e+00	474.9	COG0358	DNA primase (bacterial type)	568
2918253466	153	98.65	1	151	3	148	3.1e-50	165.1	COG1610	Uncharacterized conserved protein YqeY	148
2918253467	390	98.65	12	390	4	369	0.0e+00	500.3	COG0505	Carbamoylphosphate synthase small subunit	368
2918253470	584	98.92	2	560	2	550	0.0e+00	547.6	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918253471	509	65.46	50	428	91	416	1.4e-31	104.1	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
2918253473	463	99.35	2	463	3	461	0.0e+00	761.3	COG0114	Fumarate hydratase class II	462
2918253474	83	67.65	1	79	16	84	1.9e-23	76.8	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918253475	240	95.3	5	234	5	227	3.4e-68	224	COG3821	Uncharacterized membrane protein	234
2918253477	562	91.83	303	552	7	242	3.8e-59	193.5	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918253478	369	7.09	37	145	209	245	4.4e-14	11.9	COG3540	Phosphodiesterase/alkaline phosphatase D	522
2918253478	369	22.41	174	331	302	418	4.4e-14	26.4	COG3540	Phosphodiesterase/alkaline phosphatase D	522
2918253479	363	93.09	12	362	2	351	0.0e+00	434.3	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
2918253480	174	94.51	8	174	4	158	2.8e-69	226.5	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
2918253481	151	93.23	16	142	4	127	2.1e-28	93.7	COG2346	Truncated hemoglobin YjbI	133
2918253482	66	94.03	1	66	5	67	3.7e-20	66.8	COG5481	Uncharacterized protein	67
2918253483	364	90.76	7	361	3	326	4.6e-98	323	COG0205	6-phosphofructokinase	347
2918253484	154	86.59	2	149	15	156	2.0e-24	80.6	COG5589	Uncharacterized protein	164
2918253487	225	96.15	7	225	4	203	6.0e-51	167.6	COG0288	Carbonic anhydrase	207
2918253488	207	97.38	13	200	3	188	6.1e-81	265.2	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
2918253489	199	72.17	1	198	7	172	7.7e-80	262.6	COG3820	Uncharacterized protein	230
2918253490	339	100	9	333	1	331	2.9e-108	356.8	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918253491	61	75.38	1	61	16	64	2.0e-16	54.9	COG5509	Uncharacterized small protein, DUF1192 family	65
2918253492	268	88.93	4	268	26	282	5.6e-38	125.5	COG5473	Uncharacterized membrane protein	290
2918253494	1109	14.77	257	408	279	378	2.5e-52	12.7	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2918253494	1109	19.65	843	1095	411	543	2.5e-52	23.1	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2918253494	1109	37.96	14	281	5	261	2.5e-52	142.9	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2918253495	116	76.7	1	97	13	91	1.2e-21	71.6	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
2918253496	167	95.78	1	167	8	166	3.7e-51	168	COG5465	Uncharacterized protein	166
2918253497	280	97.76	14	280	4	265	2.3e-75	248.1	COG0345	Pyrroline-5-carboxylate reductase	266
2918253498	172	88.39	20	171	13	149	4.5e-35	115.3	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
2918253499	224	87.08	18	214	19	200	3.5e-12	41.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918253500	145	74.68	10	138	39	156	5.5e-18	60	COG5490	Uncharacterized protein	158
2918253501	111	64.08	1	110	10	100	1.4e-19	65	COG0073	tRNA-binding EMAP/Myf domain	123
2918253502	649	76.47	125	548	78	402	2.2e-55	182.6	COG0840	Methyl-accepting chemotaxis protein	408
2918253503	225	91.21	1	223	13	230	3.6e-17	56.6	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918253504	464	84.01	9	464	57	387	6.4e-52	171.2	COG0642	Signal transduction histidine kinase	336
2918253505	233	99.14	6	233	2	231	6.1e-72	236.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918253507	162	95.49	14	143	5	131	1.8e-20	67.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918253508	297	99.3	10	292	2	284	6.6e-85	280.1	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2918253509	753	96	2	607	2	553	4.7e-117	386.5	COG0550	DNA topoisomerase IA	570
2918253510	246	78.21	3	240	41	241	1.4e-13	43	COG3591	V8-like Glu-specific endopeptidase	251
2918253511	115	92.65	1	115	9	134	4.3e-30	99.1	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918253512	713	99.04	1	713	4	725	0.0e+00	832.2	COG0480	Translation elongation factor EF-G, a GTPase	697
2918253513	177	32.07	10	174	189	306	4.6e-11	38	COG0457	Tetratricopeptide (TPR) repeat	291
2918253515	498	99.16	26	495	3	476	0.0e+00	581.6	COG0469	Pyruvate kinase	477
2918253516	122	100	1	122	1	121	1.0e-52	172.3	COG0099	Ribosomal protein S13	121
2918253517	132	96.92	1	132	5	130	2.0e-61	200.8	COG0100	Ribosomal protein S11	129
2918253518	338	99.37	9	329	3	319	1.9e-121	399.7	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
2918253519	144	100	1	116	1	116	3.3e-51	167	COG0203	Ribosomal protein L17	116
2918253520	192	97.52	1	164	1	157	2.5e-43	142.1	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
2918253521	86	13.88	6	76	233	286	1.1e-03	12.6	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918253523	342	95	6	340	12	353	7.1e-62	202.8	COG0628	Predicted PurR-regulated permease PerM	355
2918253524	511	50.13	275	509	17	208	7.3e-46	18.9	COG0477	MFS family permease	338
2918253524	511	83.81	13	299	2	322	7.3e-46	137	COG0477	MFS family permease	338
2918253525	208	83.98	6	202	3	196	4.4e-31	103.1	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918253526	251	97.59	5	249	7	249	7.1e-46	151.4	COG1651	Protein-disulfide isomerase	244
2918253527	457	85.77	11	453	55	470	1.5e-93	308.7	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2918253529	385	96.72	6	385	8	390	1.2e-102	338.6	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918253530	280	86.67	18	279	31	277	2.8e-52	172.1	COG0061	NAD kinase	281
2918253531	772	41.49	415	751	469	802	0.0e+00	459.6	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918253531	772	49.69	1	423	2	401	0.0e+00	522.9	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918253532	108	88.79	3	108	12	106	3.1e-44	144	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
2918253533	158	79.75	1	155	26	151	2.3e-20	66.1	COG5490	Uncharacterized protein	158
2918253534	170	29.11	1	50	111	156	5.5e-23	4.1	COG5490	Uncharacterized protein	158
2918253534	170	77.85	31	167	33	155	5.5e-23	75.9	COG5490	Uncharacterized protein	158
2918253535	251	95.29	1	245	1	243	1.0e-46	153.8	COG3484	Predicted proteasome-type protease	255
2918253537	419	96.18	1	380	13	390	1.5e-113	374.5	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2918253538	256	91.73	7	225	4	125	1.9e-31	103.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918253539	171	81.71	17	166	19	152	6.0e-52	170	COG5321	Uncharacterized protein	164
2918253540	572	79.44	170	558	78	390	3.9e-72	238.2	COG0642	Signal transduction histidine kinase	336
2918253541	468	57.61	23	323	165	391	9.6e-39	128.5	COG0642	Signal transduction histidine kinase	336
2918253541	468	93.98	338	466	6	130	6.9e-18	58.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918253542	718	66.75	246	716	127	389	2.2e-45	148	COG0642	Signal transduction histidine kinase	336
2918253543	489	15.9	187	261	22	73	7.5e-67	18.4	COG0280	Phosphotransacetylase	327
2918253543	489	66.97	254	481	107	325	7.5e-67	204.9	COG0280	Phosphotransacetylase	327
2918253543	489	90.57	18	165	12	155	1.5e-22	73.6	COG2030	Acyl dehydratase	159
2918253544	398	98.74	7	398	2	394	0.0e+00	435.8	COG0282	Acetate kinase	396
2918253546	550	99.12	40	540	4	452	0.0e+00	643.5	COG0166	Glucose-6-phosphate isomerase	446
2918253548	451	94.97	20	444	15	429	1.5e-77	255.6	COG0612	Predicted Zn-dependent peptidase	438
2918253549	460	94.74	32	459	18	431	8.1e-110	361.9	COG0612	Predicted Zn-dependent peptidase	438
2918253551	167	92.22	5	167	9	162	4.5e-43	141.2	COG0597	Lipoprotein signal peptidase	167
2918253552	946	99.47	3	946	2	943	0.0e+00	1094.1	COG0060	Isoleucyl-tRNA synthetase	933
2918253553	62	89.86	1	62	1	62	4.9e-22	72.2	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918253554	167	93.87	1	161	6	158	1.0e-56	185.5	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
2918253555	390	96.86	233	389	1	154	2.5e-63	205.8	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
2918253555	390	97.41	1	228	3	228	1.8e-69	228	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
2918253556	280	89.06	5	276	28	263	1.1e-32	108.5	COG4137	ABC-type uncharacterized transport system, permease component	265
2918253557	328	98.15	3	322	2	320	1.0e-113	374.4	COG0042	tRNA-dihydrouridine synthase	323
2918253558	393	96.97	20	382	8	359	5.4e-128	421.5	COG3852	Signal transduction histidine kinase, nitrogen specific	363
2918253559	481	98.07	1	479	4	461	0.0e+00	586.4	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918253560	772	98.03	26	748	11	708	0.0e+00	739.5	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
2918253561	466	98.5	1	462	4	463	0.0e+00	549.1	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918253562	265	88.58	7	265	25	280	5.5e-77	253.6	COG5473	Uncharacterized membrane protein	290
2918253563	645	94.07	37	634	35	621	7.1e-125	412.2	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918253564	741	93.78	25	583	28	555	1.1e-66	219.8	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2918253565	480	98.28	3	344	5	346	6.8e-107	351.9	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2918253566	183	89.25	7	178	15	180	2.2e-49	162.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918253567	271	98.44	5	269	4	256	3.3e-53	175.7	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2918253568	128	30.77	1	58	1	52	7.4e-46	80.2	COG5352	Uncharacterized protein	169
2918253568	128	33.14	51	119	112	167	7.4e-46	71.8	COG5352	Uncharacterized protein	169
2918253569	630	96.27	177	623	13	373	6.2e-41	134.3	COG4585	Signal transduction histidine kinase	365
2918253570	230	99.05	16	227	2	210	4.7e-52	171.3	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918253572	98	21.27	3	80	44	100	6.8e-03	10.4	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2918253578	366	79.42	1	295	16	235	3.3e-36	119.8	COG3723	Recombinational DNA repair protein RecT	276
2918253580	197	65.75	1	197	21	187	1.2e-17	59.3	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2918253581	366	32.23	15	359	96	338	4.4e-01	3.7	COG0643	Chemotaxis protein histidine kinase CheA	716
2918253594	63	19.49	1	55	1	46	2.5e-03	12.2	COG3637	Opacity protein and related surface antigens	199
2918253599	164	70.59	52	142	14	85	2.0e-15	50.5	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918253603	249	91.74	36	240	17	216	1.4e-36	120.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918253607	171	68.75	32	101	19	73	1.0e-34	53.1	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918253607	171	76.25	97	168	18	78	1.0e-34	58.6	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918253609	278	74.78	1	276	70	324	1.3e-62	207	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918253616	262	84.81	186	258	3	69	1.4e-22	72.8	COG5565	Bacteriophage terminase large (ATPase) subunit and inactivated derivatives	79
2918253623	71	9.71	2	67	419	471	3.5e-03	10.6	COG4615	ABC-type siderophore export system, fused ATPase and permease components	546
2918253633	228	95.39	1	153	5	149	1.5e-40	132.9	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
2918253643	70	17.81	5	66	55	93	3.9e-03	10.6	COG3897	Predicted nicotinamide N-methyase	218
2918253648	445	98.78	6	421	3	406	1.8e-34	114.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918253650	467	92.42	34	449	3	380	4.3e-28	92.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918253651	275	70.97	12	272	30	227	2.0e-13	45.6	COG0500	SAM-dependent methyltransferase	257
2918253652	771	74.76	472	734	3	236	1.9e-25	84	COG1216	Glycosyltransferase, GT2 family	305
2918253653	273	9.82	1	58	398	452	2.3e-37	36	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918253653	273	16.07	57	138	371	460	2.3e-37	48.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918253653	273	22.5	132	271	396	521	2.3e-37	50.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918253654	458	97.95	25	449	8	389	1.4e-29	98.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918253655	578	95	2	570	15	565	0.0e+00	696.1	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2918253656	337	99.39	5	329	2	328	4.8e-130	427.9	COG1087	UDP-glucose 4-epimerase	329
2918253657	179	78.2	33	167	7	110	6.1e-17	56.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918253658	407	85.44	14	360	9	319	1.3e-33	111.3	COG5330	Uncharacterized conserved protein, DUF2336 family	364
2918253660	45	5.06	1	40	411	432	2.3e-04	14.8	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918253662	114	17.5	5	111	18	108	8.7e-03	9.4	COG0815	Apolipoprotein N-acyltransferase	518
2918253663	195	94.03	7	73	3	65	7.5e-27	54.9	COG1278	Cold shock protein, CspA family	67
2918253663	195	98.51	129	195	1	66	7.5e-27	31.5	COG1278	Cold shock protein, CspA family	67
2918253664	461	97.34	7	452	9	410	0.0e+00	443.9	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2918253665	351	93.57	1	351	14	377	1.1e-49	164.1	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918253666	325	96.72	1	308	10	304	3.1e-100	329.8	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
2918253667	196	88.52	1	195	12	196	2.0e-24	82.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918253668	285	92.44	6	285	13	281	6.2e-106	348.6	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
2918253669	403	99.23	17	399	2	386	0.0e+00	475.5	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
2918253671	546	85.88	29	541	60	424	7.7e-61	200.8	COG0840	Methyl-accepting chemotaxis protein	408
2918253672	454	67.53	141	448	137	423	5.6e-53	175.1	COG0840	Methyl-accepting chemotaxis protein	408
2918253673	348	96.88	3	348	9	349	1.6e-95	314.5	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
2918253674	936	66.24	488	799	129	389	1.8e-54	179.5	COG0642	Signal transduction histidine kinase	336
2918253674	936	85.71	814	935	6	119	2.7e-19	62.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918253675	382	96.73	2	382	13	396	1.9e-110	363.9	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2918253676	331	86.15	43	328	4	227	3.7e-31	103.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918253677	426	93.5	1	426	27	443	0.0e+00	602	COG3487	Uncharacterized iron-regulated protein	446
2918253678	487	99.38	11	487	1	481	1.4e-89	296.2	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2918253679	428	88.98	8	428	51	478	2.2e-127	413.5	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
2918253680	371	96.38	1	371	14	359	2.1e-45	150.2	COG3489	Predicted periplasmic lipoprotein	359
2918253681	373	90.16	1	373	35	364	9.2e-96	315.5	COG3490	Uncharacterized protein	366
2918253682	361	73.02	11	358	84	378	5.3e-35	116	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918253683	181	98.21	6	170	3	167	1.4e-51	169.9	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2918253684	436	97.16	12	436	6	450	4.2e-109	359.9	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2918253685	434	91.78	336	409	3	69	7.2e-12	39.1	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2918253685	434	99.35	3	323	2	309	1.7e-76	251.8	COG0167	Dihydroorotate dehydrogenase	310
2918253686	415	98.56	11	413	4	415	1.1e-59	197.2	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918253687	229	96.17	9	215	3	203	2.6e-26	88.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918253688	479	98.61	1	448	2	426	1.6e-122	404.1	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2918253689	298	98.01	5	291	2	296	1.8e-54	180.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918253691	191	95.85	1	191	7	191	1.7e-60	198.6	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
2918253692	335	100	1	324	1	322	5.2e-122	401.6	COG0435	Glutathionyl-hydroquinone reductase	324
2918253693	404	96.4	27	401	2	349	0.0e+00	434.4	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2918253694	225	93.97	5	225	7	224	1.5e-51	169.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918253695	242	99.17	1	240	2	241	1.4e-109	359.5	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918253696	984	9.54	115	176	6	42	3.7e-68	20.5	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918253696	984	14.95	169	270	158	215	3.7e-68	10	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918253696	984	84.13	496	559	4	56	9.1e-03	11	COG2906	Bacterioferritin-associated ferredoxin	63
2918253696	984	98.2	602	984	2	382	3.7e-68	214	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918253697	305	97.99	1	295	3	295	8.3e-93	305	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918253698	276	95.76	1	266	2	272	2.9e-38	126.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918253699	231	92.54	2	222	16	226	1.9e-71	234.9	COG0765	ABC-type amino acid transport system, permease component	222
2918253700	230	93.53	5	226	12	228	5.6e-50	164.4	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918253701	474	99.54	4	454	2	430	2.2e-109	360.8	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2918253703	75	16.17	1	72	221	269	2.9e-05	18.3	COG1234	Ribonuclease BN, tRNA processing enzyme	292
2918253704	62	18.29	2	61	72	118	9.7e-05	17.1	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2918253707	150	97.95	9	131	2	144	1.8e-11	39.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918253708	311	98.01	13	309	2	296	4.6e-40	132.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918253710	220	91.87	1	202	10	201	2.7e-23	78.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918253711	571	96.24	64	464	12	395	2.5e-63	209.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918253712	202	91.39	2	200	14	204	2.0e-19	65.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918253713	525	98.38	1	479	2	486	3.6e-118	389.7	COG2368	Aromatic ring hydroxylase	493
2918253715	365	97.44	4	365	2	344	1.7e-126	416.8	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918253716	297	93.33	25	297	2	253	1.8e-71	235.2	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918253717	173	85.45	3	171	18	158	2.2e-34	112.9	COG0835	Chemotaxis signal transduction protein	165
2918253718	738	24.71	216	392	42	146	4.6e-78	30.9	COG0840	Methyl-accepting chemotaxis protein	408
2918253718	738	75.53	387	666	104	424	4.6e-78	241.4	COG0840	Methyl-accepting chemotaxis protein	408
2918253719	150	84.85	1	150	14	153	4.7e-31	102.3	COG0835	Chemotaxis signal transduction protein	165
2918253720	674	15.65	4	135	11	128	0.0e+00	80.4	COG0643	Chemotaxis protein histidine kinase CheA	716
2918253720	674	73.61	115	673	191	745	0.0e+00	554.1	COG0643	Chemotaxis protein histidine kinase CheA	716
2918253721	122	90.98	1	122	6	126	1.5e-34	113.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918253722	107	49.49	18	91	31	79	3.6e-03	12.2	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
2918253723	409	97.1	82	399	2	302	1.1e-56	186.6	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918253724	426	98.87	7	424	4	441	3.4e-66	219.1	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918253725	313	95.3	19	312	8	291	1.1e-81	269	COG1175	ABC-type sugar transport system, permease component	295
2918253726	275	96.47	2	274	11	283	3.3e-90	296.9	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918253727	511	92.59	14	482	34	458	4.0e-122	402.8	COG0165	Argininosuccinate lyase	459
2918253728	370	99.71	1	357	1	349	0.0e+00	445.1	COG3839	ABC-type sugar transport system, ATPase component	338
2918253729	301	96.52	9	301	2	306	7.2e-46	151.3	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918253730	343	99.71	4	342	2	340	2.0e-86	284.8	COG2222	Fructoselysine-6-P-deglycase FrlB and related proteins with duplicated sugar isomerase (SIS) domain	340
2918253732	781	72.55	238	526	92	358	9.6e-44	65	COG0457	Tetratricopeptide (TPR) repeat	291
2918253732	781	82.07	3	257	51	352	9.6e-44	83.9	COG0457	Tetratricopeptide (TPR) repeat	291
2918253734	214	94.09	30	207	5	179	8.8e-46	150.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918253735	159	90.91	5	136	5	124	7.0e-13	43.2	COG1516	Flagellin-specific chaperone FliS	132
2918253736	563	93.98	7	559	11	478	6.3e-50	165	COG1345	Flagellar capping protein FliD	483
2918253737	274	27.84	164	274	281	388	4.8e-65	70.9	COG1344	Flagellin and related hook-associated protein FlgL	360
2918253737	274	45.1	3	179	2	176	4.8e-65	149.5	COG1344	Flagellin and related hook-associated protein FlgL	360
2918253738	304	22.94	196	304	296	384	1.8e-21	34.2	COG1344	Flagellin and related hook-associated protein FlgL	360
2918253738	304	49.48	2	231	2	193	1.8e-21	41.1	COG1344	Flagellin and related hook-associated protein FlgL	360
2918253739	581	98.64	1	581	8	587	5.0e-67	221.8	COG1256	Flagellar hook-associated protein FlgK	552
2918253741	217	98.58	4	207	2	209	1.9e-46	153	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918253742	1040	99.51	7	1037	2	807	1.5e-127	421.6	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918253743	377	95.41	6	317	11	301	6.2e-20	65.2	COG3301	Formate-dependent nitrite reductase, membrane component NrfD	305
2918253744	249	91.22	31	227	9	195	1.2e-66	218.6	COG0437	Fe-S-cluster-containing dehydrogenase component	203
2918253745	215	97.52	13	214	4	200	7.3e-77	252.1	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918253746	647	72.08	22	275	7	210	1.1e-03	8.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918253746	647	78.43	270	637	81	389	3.6e-59	195.4	COG0642	Signal transduction histidine kinase	336
2918253747	265	88.58	6	265	27	282	3.1e-32	106.7	COG5473	Uncharacterized membrane protein	290
2918253748	846	99.64	1	841	3	828	0.0e+00	494.8	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
2918253749	356	78.79	200	333	21	124	5.3e-18	59.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918253750	959	81.58	346	953	131	710	0.0e+00	483.4	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918253751	719	99.16	9	719	3	707	0.0e+00	628	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918253752	415	70.45	24	344	48	295	7.3e-20	65.2	COG1566	Multidrug resistance efflux pump	352
2918253761	344	81.06	203	329	23	129	4.1e-21	69.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918253763	436	99.58	3	436	3	472	4.2e-87	287.1	COG1749	Flagellar hook protein FlgE	423
2918253764	224	93.72	1	223	8	216	1.7e-43	143.5	COG1843	Flagellar hook assembly protein FlgD	222
2918253766	307	96.68	2	298	1	291	1.8e-63	209.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918253767	223	89.62	7	220	10	199	7.2e-61	199.9	COG0684	Regulator of RNase E activity RraA	210
2918253768	348	97.99	1	346	4	345	3.0e-115	379.4	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
2918253769	387	98.68	7	387	4	377	1.3e-128	423.7	COG1454	Alcohol dehydrogenase, class IV	377
2918253770	491	98.54	15	491	3	474	0.0e+00	513.8	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918253771	328	96.99	1	328	4	325	3.1e-92	304.1	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918253772	192	83.05	29	189	7	153	9.7e-33	107.6	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918253773	435	99.47	46	435	1	377	0.0e+00	450.8	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918253774	426	98.58	6	426	6	421	0.0e+00	515.4	COG2379	Glycerate-2-kinase	422
2918253775	336	85.93	20	331	39	319	3.4e-80	263.8	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918253776	373	58.52	101	367	128	333	5.2e-67	221.3	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2918253777	502	98.35	10	495	8	485	0.0e+00	633.7	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
2918253778	422	97.74	100	413	1	303	3.9e-46	152	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918253779	440	47.52	205	419	8	189	4.4e-31	9.5	COG0477	MFS family permease	338
2918253779	440	74.93	5	254	9	295	4.4e-31	97.6	COG0477	MFS family permease	338
2918253780	162	90.23	10	142	12	131	2.6e-24	80.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918253781	223	93.3	17	222	12	206	4.2e-28	94	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918253782	276	36.48	5	146	68	125	2.6e-18	3.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918253782	276	62.89	140	276	57	156	2.6e-18	61.4	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918253783	242	89.95	29	236	16	203	3.2e-27	91.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918253784	406	96.41	1	380	13	388	1.1e-73	243.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918253785	1056	99.8	1	1029	2	1013	0.0e+00	1235.6	COG0841	Multidrug efflux pump subunit AcrB	1009
2918253786	136	88.97	1	135	6	134	6.7e-33	108.2	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2918253787	482	11.27	2	114	40	103	1.7e-71	29	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918253787	482	66.02	113	481	184	558	1.7e-71	205.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918253788	279	88.68	1	268	2	236	3.6e-64	211.3	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918253789	413	44.39	235	411	26	195	1.4e-16	18.8	COG0477	MFS family permease	338
2918253789	413	69.71	12	278	8	274	1.4e-16	37.1	COG0477	MFS family permease	338
2918253790	412	96.72	5	390	9	362	3.5e-34	113.1	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918253791	246	95.85	4	244	8	238	7.2e-51	167.6	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918253792	335	99.4	9	333	2	330	6.4e-68	224.2	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918253794	871	90.35	395	870	37	420	1.7e-53	177.3	COG0840	Methyl-accepting chemotaxis protein	408
2918253796	159	97.06	14	159	3	134	2.6e-33	109.7	COG4520	Surface antigen	136
2918253800	226	35.67	114	226	111	171	1.9e-37	29.6	COG4675	Microcystin-dependent protein  (function unknown)	170
2918253800	226	74.85	1	151	1	128	1.9e-37	95.8	COG4675	Microcystin-dependent protein  (function unknown)	170
2918253802	226	100	1	226	1	171	8.4e-40	116.5	COG4675	Microcystin-dependent protein  (function unknown)	170
2918253805	670	96.74	24	486	2	446	1.8e-18	61	COG1538	Outer membrane protein TolC	457
2918253806	266	22.16	1	123	50	127	3.4e-21	31.6	COG1566	Multidrug resistance efflux pump	352
2918253806	266	32.95	96	231	176	291	3.4e-21	40.3	COG1566	Multidrug resistance efflux pump	352
2918253807	457	16.76	186	285	52	110	5.1e-09	19.8	COG1566	Multidrug resistance efflux pump	352
2918253807	457	35.51	253	400	149	273	5.1e-09	14.6	COG1566	Multidrug resistance efflux pump	352
2918253808	735	25.28	424	556	54	142	2.3e-10	17	COG1566	Multidrug resistance efflux pump	352
2918253808	735	28.98	529	642	189	290	2.3e-10	18.3	COG1566	Multidrug resistance efflux pump	352
2918253809	543	83.76	105	542	56	385	1.0e-72	240.2	COG0642	Signal transduction histidine kinase	336
2918253810	385	96.72	5	384	8	390	1.8e-94	311.4	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918253813	591	99.17	15	590	3	481	1.5e-104	344.7	COG0471	Di- and tricarboxylate transporter	461
2918253814	669	97.64	1	635	8	668	6.3e-72	237.5	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2918253818	302	97.01	8	293	6	297	3.3e-43	142.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918253819	400	98.25	1	400	8	401	0.0e+00	529	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918253820	428	96.19	1	426	17	445	0.0e+00	550.9	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2918253821	486	98.75	12	486	3	475	0.0e+00	621.8	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918253822	188	70.77	4	121	2	93	1.0e-17	59.3	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918253823	276	97.38	8	273	5	264	1.7e-82	271.2	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918253824	416	76.04	131	413	60	278	3.7e-85	280.2	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918253825	348	92.06	1	348	11	358	3.0e-63	208.8	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918253826	365	98.87	4	364	3	351	9.0e-125	411.2	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918253827	363	99.17	1	357	2	361	0.0e+00	501.7	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
2918253829	542	96.17	348	530	6	181	1.1e-51	169.3	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918253830	356	95.7	1	356	1	334	0.0e+00	473.6	COG4307	Uncharacterized protein	349
2918253831	765	97.87	2	714	9	697	0.0e+00	900.4	COG1523	Pullulanase/glycogen debranching enzyme	697
2918253832	427	97.96	2	426	4	436	3.2e-84	275.9	COG1486	Alpha-galactosidase/6-phospho-beta-glucosidase, family 4 of glycosyl hydrolase	442
2918253833	441	98.27	3	441	3	457	8.0e-128	421.6	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2918253834	607	95.55	10	603	23	602	0.0e+00	494.4	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
2918253835	258	97.89	1	257	1	232	5.7e-53	175	COG3416	Uncharacterized protein	233
2918253837	221	72.28	1	197	10	155	1.0e-24	81.7	COG1776	Chemotaxis protein CheY-P-specific phosphatase CheC	203
2918253838	629	97.37	251	617	3	224	1.8e-52	172.2	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918253839	135	50.43	1	131	1	117	9.4e-14	45.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918253840	283	96.81	1	282	8	280	5.7e-56	184.3	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918253841	267	95.05	1	267	6	274	1.3e-52	173.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918253842	224	93.42	2	220	13	225	1.0e-65	216.1	COG0765	ABC-type amino acid transport system, permease component	222
2918253843	216	93.42	2	216	15	227	7.2e-70	229.7	COG0765	ABC-type amino acid transport system, permease component	222
2918253844	244	98.76	2	242	2	240	6.4e-102	334.4	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918253845	336	97.13	1	336	10	348	9.6e-67	218.7	COG5042	Purine nucleoside permease	349
2918253846	232	87.86	1	232	1	246	2.0e-63	209.2	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2918253847	361	96.95	9	361	2	351	1.4e-99	327.8	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2918253850	106	53.54	1	71	4	56	3.6e-06	21.7	COG3668	Plasmid stabilization system protein ParE	98
2918253851	197	92.82	2	196	9	202	1.2e-23	79.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918253852	251	99.63	2	249	1	267	9.7e-76	249.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918253853	396	99.49	4	395	2	393	3.1e-121	399.8	COG0183	Acetyl-CoA acetyltransferase	392
2918253854	429	51.17	236	428	2	197	3.4e-20	33.3	COG0477	MFS family permease	338
2918253854	429	52.48	10	235	8	208	3.4e-20	40.4	COG0477	MFS family permease	338
2918253855	344	98.01	2	298	2	296	3.9e-74	244.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918253856	287	83.96	4	278	51	317	1.2e-55	183.9	COG0657	Acetyl esterase/lipase	312
2918253857	393	95.38	1	378	12	383	6.7e-58	191.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918253858	1067	99.9	2	1044	1	1013	0.0e+00	1179.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2918253859	176	93.92	4	143	2	140	1.8e-24	81.1	COG0394	Protein-tyrosine-phosphatase	139
2918253861	405	96.17	11	381	10	361	1.8e-39	130.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918253862	354	92.66	15	340	10	312	2.3e-76	251.6	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2918253863	420	99	1	404	1	395	8.2e-90	296.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918253864	323	100	1	323	1	331	2.1e-89	294.8	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918253865	294	65.41	153	285	19	122	7.9e-23	75.3	COG2030	Acyl dehydratase	159
2918253866	520	96.3	17	520	10	556	9.6e-117	385.2	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918253867	268	89.63	21	248	11	226	1.1e-40	134.1	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918253868	383	97.47	11	373	5	351	8.0e-119	391.4	COG3569	DNA topoisomerase IB	354
2918253869	658	79.08	350	648	74	364	3.2e-36	119.3	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2918253870	567	88.24	132	562	49	423	1.8e-54	180.5	COG0840	Methyl-accepting chemotaxis protein	408
2918253871	299	89	69	294	11	196	2.1e-24	81.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918253872	222	92.98	2	219	14	225	4.9e-67	220.3	COG0765	ABC-type amino acid transport system, permease component	222
2918253873	218	91.67	1	216	18	226	5.3e-70	230.3	COG0765	ABC-type amino acid transport system, permease component	222
2918253874	283	93.99	8	273	9	274	5.8e-49	161.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918253875	268	98.76	25	265	3	241	1.4e-113	372.6	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918253876	152	93.15	3	148	3	138	4.1e-63	206	COG0757	3-dehydroquinate dehydratase	146
2918253877	356	98.86	11	354	3	349	5.5e-67	219.7	COG0673	Predicted dehydrogenase	342
2918253878	648	92.81	11	276	5	262	3.5e-55	181.1	COG1082	Sugar phosphate isomerase/epimerase	274
2918253878	648	95.04	277	645	15	359	9.1e-112	368.1	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
2918253879	302	95.77	16	298	8	279	7.5e-85	278.9	COG0169	Shikimate 5-dehydrogenase	283
2918253880	287	91.89	13	156	13	148	2.0e-15	51.3	COG5501	Predicted secreted protein	148
2918253881	322	77.31	35	314	20	220	5.0e-21	70	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918253883	346	90.91	14	346	25	324	7.0e-45	148	COG3528	Uncharacterized protein	330
2918253885	340	95.99	9	340	6	340	3.9e-95	313.4	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
2918253887	331	90.29	2	331	24	339	6.7e-80	263.6	COG3768	Uncharacterized membrane protein YcjF, UPF0283 family	350
2918253888	463	97.83	5	463	10	459	0.0e+00	508.9	COG3106	Predicted ATPase, YcjX-like family	467
2918253891	137	93.23	12	137	6	129	7.9e-36	117.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918253892	207	94.42	5	206	2	204	4.9e-45	148.7	COG0625	Glutathione S-transferase	211
2918253893	538	73.1	199	538	101	388	4.2e-38	126.9	COG0642	Signal transduction histidine kinase	336
2918253894	275	98.71	7	246	2	230	2.2e-43	142.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918253896	419	83.03	18	335	3	320	2.2e-17	57.6	COG0477	MFS family permease	338
2918253897	299	68.52	5	299	2	284	6.1e-68	224.4	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918253898	671	99.69	5	668	1	644	0.0e+00	885.1	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918253899	260	98.11	1	258	6	265	3.3e-69	227.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918253900	535	99.62	12	535	2	525	0.0e+00	695.6	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2918253901	377	97.49	1	377	5	393	0.0e+00	465.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918253902	395	99.49	3	394	3	394	1.4e-122	404.2	COG0183	Acetyl-CoA acetyltransferase	392
2918253903	390	98.75	9	390	2	395	0.0e+00	439.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918253904	409	94.29	1	405	10	422	1.7e-56	184.3	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
2918253905	281	98.73	20	260	3	236	2.8e-90	296.2	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918253906	431	88.25	10	403	6	328	9.8e-21	68.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918253907	357	96.28	25	349	9	319	6.3e-78	256.8	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918253908	295	98.67	1	294	2	298	1.9e-65	216	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918253909	649	97.72	5	610	12	610	0.0e+00	463.5	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2918253910	278	99.21	6	260	3	254	1.7e-97	320.3	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918253911	557	78.44	128	556	11	443	2.8e-88	291	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918253912	190	83.25	1	188	14	187	1.0e-19	66.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918253913	988	85.41	261	718	56	418	4.4e-47	156.1	COG0840	Methyl-accepting chemotaxis protein	408
2918253914	163	96.2	1	156	4	155	2.3e-44	145.9	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918253915	332	95.68	5	330	10	319	7.7e-97	318.8	COG0385	Predicted Na+-dependent transporter	319
2918253916	213	97.21	1	213	1	209	9.2e-51	167.5	COG0625	Glutathione S-transferase	211
2918253917	471	98.75	10	467	4	478	2.5e-109	361	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918253918	380	90.65	21	368	6	325	2.7e-115	379.9	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918253919	348	94.71	1	346	6	363	4.6e-38	125.8	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918253920	285	92.71	2	284	14	280	6.7e-81	266.3	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918253921	270	94.38	8	269	9	260	8.7e-71	232.8	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918253922	117	93.55	1	117	8	123	9.0e-20	65.8	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
2918253923	396	43.86	215	394	20	187	6.2e-10	11	COG0477	MFS family permease	338
2918253923	396	53.26	10	241	8	211	6.2e-10	25.7	COG0477	MFS family permease	338
2918253924	467	97.09	6	463	7	473	1.9e-117	387.6	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918253925	238	92.67	10	236	10	224	4.5e-55	181.2	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918253926	478	99.3	3	453	2	429	2.1e-115	380.6	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2918253927	243	98.32	1	241	4	237	2.1e-37	123.7	COG3473	Maleate cis-trans isomerase	238
2918253928	443	97.41	5	437	5	417	4.2e-82	270.4	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918253929	261	97.61	1	256	3	247	2.2e-94	310.3	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918253930	268	95.74	1	262	10	256	6.4e-82	269.6	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918253931	340	83.58	1	332	6	285	5.0e-32	106	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918253932	237	96.98	3	232	4	228	4.9e-59	194.3	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918253934	277	86.89	33	276	25	256	8.0e-71	232.8	COG1526	Formate dehydrogenase assembly factor FdhD	266
2918253935	951	21.78	16	238	5	217	0.0e+00	273.9	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2918253935	951	71.17	234	949	263	958	0.0e+00	945.9	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2918253936	526	98.35	97	518	3	419	0.0e+00	549.6	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2918253937	174	87.95	2	157	16	161	1.9e-50	165.1	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2918253938	316	94.35	1	297	4	287	4.4e-48	159.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918253939	32	6.6	1	31	440	470	8.0e-12	39.7	COG1282	NAD/NADP transhydrogenase beta subunit	463
2918253941	1361	77.64	10	594	138	689	0.0e+00	375.7	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918253941	1361	94.51	633	1314	17	688	0.0e+00	449	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918253942	436	96.15	7	426	13	387	7.7e-36	118.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918253945	428	99.21	46	427	2	377	3.5e-109	359.4	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918253946	168	82.49	16	168	14	159	2.3e-31	103.2	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918253948	244	95.67	1	242	10	230	1.2e-63	209.6	COG2063	Flagellar basal body L-ring protein FlgH	230
2918253949	253	56.36	80	235	96	219	1.2e-26	88.3	COG1261	Flagella basal body P-ring formation protein FlgA	220
2918253950	261	98.87	1	261	2	263	1.0e-89	295.2	COG4786	Flagellar basal body rod protein FlgG	265
2918253951	243	99.62	1	240	1	264	7.8e-60	196.8	COG4786	Flagellar basal body rod protein FlgG	265
2918253952	833	66.3	281	825	66	309	2.8e-05	13.9	COG0457	Tetratricopeptide (TPR) repeat	291
2918253953	295	97.38	1	285	3	262	3.3e-74	243.8	COG1291	Flagellar motor component MotA	266
2918253954	345	99.26	11	343	2	269	2.1e-55	182.7	COG1360	Flagellar motor protein MotB	244
2918253955	399	97.67	1	399	12	472	3.5e-73	236.9	COG1749	Flagellar hook protein FlgE	423
2918253956	482	15.31	265	482	498	587	1.7e-70	55.8	COG1256	Flagellar hook-associated protein FlgK	552
2918253956	482	40.82	1	330	1	240	1.7e-70	183	COG1256	Flagellar hook-associated protein FlgK	552
2918253957	367	97.68	5	367	7	385	2.5e-14	43.3	COG1344	Flagellin and related hook-associated protein FlgL	360
2918253958	378	98.63	9	378	6	365	1.3e-129	426.8	COG1706	Flagellar basal body P-ring protein FlgI	365
2918253959	111	57.89	1	111	16	114	6.1e-07	24.7	COG3951	Rod binding protein domain	166
2918253963	409	97.44	13	389	5	309	6.4e-91	299.2	COG2421	Acetamidase/formamidase	305
2918253964	805	81.18	3	393	79	423	1.7e-51	169.8	COG0840	Methyl-accepting chemotaxis protein	408
2918253964	805	96.45	405	788	6	358	1.5e-56	186.9	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918253965	229	95.36	1	229	3	228	1.4e-83	274.4	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918253966	248	95.7	1	248	9	253	3.8e-108	355.5	COG4674	ABC-type uncharacterized transport system, ATPase component	249
2918253967	369	96.9	1	341	9	321	6.8e-74	243.7	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918253968	308	98.34	11	308	4	299	1.5e-85	282	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918253969	419	96.72	30	407	9	362	1.2e-59	196.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918253970	1146	78.68	536	902	76	385	1.5e-72	238.8	COG0642	Signal transduction histidine kinase	336
2918253970	1146	82.81	31	491	31	401	3.7e-19	63.4	COG1457	Purine-cytosine permease or related protein	442
2918253970	1146	90.23	918	1053	6	125	6.3e-26	83.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918253971	306	36.97	209	305	129	206	5.5e-39	65.4	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918253971	306	57.82	5	161	3	124	5.5e-39	61.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918253972	390	47.78	206	389	8	190	1.7e-15	28.8	COG0477	MFS family permease	338
2918253972	390	53	17	223	9	211	1.7e-15	26.4	COG0477	MFS family permease	338
2918253973	449	90.32	9	188	16	183	4.8e-07	23.2	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
2918253974	489	66.08	33	304	85	310	5.8e-35	115.3	COG0668	Small-conductance mechanosensitive channel	316
2918253975	645	15.53	287	361	93	158	4.9e-73	12	COG0840	Methyl-accepting chemotaxis protein	408
2918253975	645	25.88	77	285	55	164	4.9e-73	26.2	COG0840	Methyl-accepting chemotaxis protein	408
2918253975	645	77.18	342	644	98	425	4.9e-73	209.9	COG0840	Methyl-accepting chemotaxis protein	408
2918253977	288	89.21	11	283	15	262	9.7e-31	101.8	COG1082	Sugar phosphate isomerase/epimerase	274
2918253979	383	97.72	5	380	7	349	1.3e-59	197	COG0673	Predicted dehydrogenase	342
2918253981	300	97.21	46	299	3	246	1.8e-92	303.9	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918253982	333	95.52	1	333	9	328	5.6e-44	145.5	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918253983	267	95.74	5	262	11	257	2.2e-75	248.1	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918253984	235	91.39	13	235	11	201	1.1e-29	99.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918253985	303	98.34	6	296	2	297	9.5e-66	217.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918253986	263	98.87	1	260	4	265	1.6e-85	281.4	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918253987	229	90.85	2	229	24	291	1.4e-20	68.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918253988	242	98.88	7	241	3	267	8.7e-50	164.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918253989	199	90.91	5	198	14	203	1.1e-16	56.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918253990	261	99.25	12	259	2	267	2.4e-67	222	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918253992	384	99.21	4	384	4	379	2.3e-122	403.1	COG1454	Alcohol dehydrogenase, class IV	377
2918253993	148	94.96	8	144	5	136	6.9e-31	101.8	COG0824	Acyl-CoA thioesterase FadM	137
2918253994	400	99.24	1	400	2	392	7.9e-117	385.3	COG0183	Acetyl-CoA acetyltransferase	392
2918253995	311	93.28	13	300	3	252	2.0e-52	173	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918253996	160	84.28	3	151	21	154	1.6e-33	109.7	COG2030	Acyl dehydratase	159
2918253997	213	88.04	11	212	17	200	3.8e-25	84.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918253998	544	95.95	9	531	13	557	9.9e-85	279.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918253999	245	85.28	1	244	6	231	2.0e-49	163	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918254000	404	96.45	13	380	8	360	3.8e-44	145.7	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918254001	292	96.01	1	287	9	297	3.8e-46	152.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918254002	147	85.11	1	131	16	135	4.4e-29	95.6	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918254003	284	11.69	41	108	8	43	5.5e-05	3.2	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918254003	284	22.08	122	257	94	161	5.5e-05	12.4	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918254004	165	87.22	23	162	12	127	1.2e-19	65.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918254005	283	99.24	22	283	3	262	3.1e-127	418.3	COG3483	Tryptophan 2,3-dioxygenase (vermilion)	262
2918254006	402	95.09	1	392	19	405	0.0e+00	498.4	COG3844	Kynureninase	407
2918254007	541	97.64	30	541	4	542	0.0e+00	448.7	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918254008	131	94.85	1	131	7	135	1.5e-26	87.7	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918254009	150	94.96	6	142	5	136	1.3e-24	81.4	COG0824	Acyl-CoA thioesterase FadM	137
2918254010	401	96.74	14	401	10	395	1.2e-97	322.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918254011	274	98.87	8	271	4	265	1.0e-67	223	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918254012	267	98.88	4	264	2	266	4.6e-69	227.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918254013	784	96.69	407	772	4	354	4.8e-109	359	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918254013	784	97.46	1	390	4	386	1.6e-44	145.9	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918254014	402	95.48	1	400	8	408	2.2e-111	367.3	COG2223	Nitrate/nitrite transporter NarK	417
2918254015	565	93.75	1	248	7	261	7.4e-40	130.2	COG0631	Serine/threonine protein phosphatase PrpC	262
2918254016	453	97.22	1	453	6	459	0.0e+00	524.4	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918254017	711	79.44	297	692	76	388	8.6e-59	194.9	COG0642	Signal transduction histidine kinase	336
2918254019	304	14.61	20	90	25	69	2.5e-66	24.8	COG3058	Formate dehydrogenase maturation protein FdhE	308
2918254019	304	66.56	77	304	101	305	2.5e-66	193.1	COG3058	Formate dehydrogenase maturation protein FdhE	308
2918254020	1035	99.88	17	1033	1	809	0.0e+00	679.7	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918254021	322	95.12	16	237	8	202	1.3e-57	189.1	COG0437	Fe-S-cluster-containing dehydrogenase component	203
2918254022	208	94.5	1	208	3	208	8.5e-81	265.4	COG2864	Cytochrome b subunit of formate dehydrogenase	218
2918254023	280	92.13	13	278	21	266	8.5e-81	265.7	COG1526	Formate dehydrogenase assembly factor FdhD	266
2918254025	236	99.16	3	233	2	236	8.0e-90	294.8	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918254026	256	98.82	1	254	3	253	1.2e-93	307.8	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918254027	344	95.36	15	323	11	318	3.6e-82	270.6	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918254028	304	98.34	3	304	4	299	1.3e-76	252.6	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918254029	373	92.62	12	372	4	342	9.8e-70	230	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918254031	448	96.91	47	428	5	380	3.1e-65	215.3	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918254032	399	96.44	9	398	11	389	0.0e+00	441	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2918254033	468	42.86	6	140	33	110	5.2e-04	13.9	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918254033	468	93.42	128	466	12	224	1.5e-51	169.3	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918254034	154	83.46	4	138	7	117	1.1e-25	84.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918254035	787	97.47	20	773	11	741	0.0e+00	804.9	COG4251	Bacteriophytochrome (light-regulated signal transduction histidine kinase)	750
2918254037	261	72.46	1	247	32	231	3.0e-28	93.7	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2918254038	1177	59.24	739	1174	136	353	6.9e-06	18.5	COG0457	Tetratricopeptide (TPR) repeat	291
2918254038	1177	64.04	8	348	2	302	1.4e-47	157.1	COG0515	Serine/threonine protein kinase	384
2918254040	449	95.06	1	245	4	234	1.3e-76	251.5	COG3482	Uncharacterized protein	237
2918254041	411	91.27	1	398	15	380	9.4e-82	269.3	COG1944	Ribosomal protein S12 methylthiotransferase accessory factor YcaO	398
2918254043	281	92.9	69	270	12	181	4.6e-51	167.8	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918254044	262	88.6	4	257	18	258	1.6e-35	117.2	COG0631	Serine/threonine protein phosphatase PrpC	262
2918254045	800	89.6	1	674	53	724	0.0e+00	589.3	COG4251	Bacteriophytochrome (light-regulated signal transduction histidine kinase)	750
2918254046	126	86.03	3	126	16	132	1.3e-46	152.6	COG3474	Cytochrome c2	135
2918254047	388	96.34	2	388	11	378	0.0e+00	469.5	COG3448	CBS-domain-containing membrane protein	382
2918254048	74	75.81	17	74	14	60	3.8e-25	82.2	COG4459	Periplasmic nitrate reductase system, NapE component	62
2918254049	145	54.03	57	135	40	106	1.5e-20	35.6	COG1145	Ferredoxin	99
2918254049	145	55.65	1	73	40	108	1.5e-20	34.8	COG1145	Ferredoxin	99
2918254050	103	82.98	11	102	6	83	1.6e-20	67.5	COG3062	Cytoplasmic chaperone NapD for the signal peptide of periplasmic nitrate reductase NapAB	94
2918254051	830	99.63	1	830	1	807	0.0e+00	712.3	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918254052	165	78.06	2	156	32	152	1.6e-51	169	COG3043	Nitrate reductase cytochrome c-type subunit	155
2918254053	208	98.42	9	200	3	189	6.7e-88	288.2	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
2918254054	310	98.99	3	305	3	297	2.7e-102	336.7	COG3246	Uncharacterized conserved protein, DUF849 family	298
2918254055	401	97.27	10	379	9	364	5.6e-41	135.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918254056	769	99.06	34	769	3	740	0.0e+00	658.4	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918254057	330	98.25	1	328	1	281	2.3e-100	330.6	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2918254058	178	94.87	1	168	4	151	1.8e-62	204.3	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918254059	232	87.86	1	232	1	246	7.6e-58	190.9	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2918254060	309	98.67	7	303	2	298	8.2e-47	155.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918254061	295	75.76	168	292	21	120	2.9e-23	76.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918254062	251	98.13	1	250	5	267	1.8e-55	183	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918254063	369	95.36	9	368	6	354	9.2e-87	286	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918254064	415	98.51	5	414	6	403	2.4e-121	400.4	COG0162	Tyrosyl-tRNA synthetase	401
2918254066	209	23.86	1	74	2	64	9.5e-20	45.9	COG1192	Cellulose biosynthesis protein BcsQ	259
2918254066	209	29.92	58	187	117	195	9.5e-20	19.7	COG1192	Cellulose biosynthesis protein BcsQ	259
2918254067	190	34.33	158	190	9	31	3.5e-03	5.6	COG5481	Uncharacterized protein	67
2918254067	190	37.31	52	95	11	35	3.5e-03	4.2	COG5481	Uncharacterized protein	67
2918254068	592	66.39	4	111	18	98	3.2e-48	35.9	COG1445	Phosphotransferase system fructose-specific component IIB	122
2918254068	592	84.43	116	233	2	104	3.2e-48	122	COG1445	Phosphotransferase system fructose-specific component IIB	122
2918254068	592	97.67	245	588	3	338	0.0e+00	443.9	COG1299	Phosphotransferase system, fructose-specific IIC component	343
2918254069	316	99.03	4	316	2	308	5.0e-92	302.8	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
2918254070	849	86.62	9	149	8	130	3.6e-42	137.6	COG4668	Mannitol/fructose-specific phosphotransferase system, IIA domain	142
2918254070	849	89.89	162	249	5	84	4.3e-16	52.3	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
2918254070	849	98.08	274	840	3	565	0.0e+00	619.1	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
2918254071	333	98.5	3	328	3	331	1.0e-103	341.8	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918254072	405	97.46	12	399	6	388	0.0e+00	498.8	COG3004	Na+/H+ antiporter NhaA	390
2918254073	304	97.67	2	301	2	295	9.7e-64	210.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918254074	317	98.01	3	298	2	296	8.0e-64	210.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918254077	398	88.8	13	383	4	328	1.0e-51	170.7	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918254078	298	98.34	1	297	5	300	1.6e-69	229.4	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918254079	602	95.05	11	321	14	320	6.8e-64	210.5	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918254079	602	98.82	344	584	4	254	9.8e-91	297.9	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918254080	241	98.73	1	234	3	236	1.4e-90	297.2	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918254081	485	99.16	6	483	2	476	0.0e+00	551.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918254082	387	99.47	6	387	3	379	4.0e-113	372.8	COG1454	Alcohol dehydrogenase, class IV	377
2918254083	183	57.3	16	178	2	107	4.5e-17	57.6	COG0563	Adenylate kinase or related kinase	178
2918254084	234	93.94	4	200	4	189	5.5e-45	148.1	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2918254085	181	80.11	10	171	37	185	4.2e-24	80.2	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918254087	213	82.71	16	151	10	119	9.4e-19	62.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918254088	450	74.37	46	425	68	360	3.6e-46	153	COG0642	Signal transduction histidine kinase	336
2918254089	764	27.6	264	451	105	258	9.5e-14	17.5	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
2918254089	764	36.92	399	639	20	225	9.5e-14	31.9	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
2918254089	764	98.89	8	273	2	268	1.1e-80	264.7	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918254090	342	78.57	188	272	14	79	1.2e-03	13	COG3813	Uncharacterized protein	84
2918254091	252	98.58	31	251	3	210	3.1e-49	162.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918254092	390	100	1	390	1	353	2.6e-114	376.2	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918254093	263	96.98	2	259	4	260	1.4e-63	209.1	COG0300	Short-chain dehydrogenase	265
2918254094	79	71.62	11	79	20	72	8.1e-18	53.2	COG3729	General stress protein YciG, contains tandem KGG domains	73
2918254096	127	92.98	23	127	7	112	1.5e-22	74.3	COG0607	Rhodanese-related sulfurtransferase	110
2918254098	116	83.87	2	115	17	120	3.5e-23	76.8	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918254099	220	97.14	1	212	4	207	6.5e-84	275	COG2945	Alpha/beta superfamily hydrolase	210
2918254100	245	85.71	1	181	7	174	2.3e-74	243.6	COG1045	Serine acetyltransferase	194
2918254101	161	89.33	1	143	1	134	1.9e-48	158.9	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918254102	375	97.41	10	375	2	377	4.9e-121	399	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
2918254103	225	41.95	54	219	4	76	3.7e-04	14.4	COG1076	DnaJ-domain-containing proteins 1	174
2918254104	109	97.09	1	104	1	100	1.8e-25	83.5	COG0633	Ferredoxin	102
2918254105	374	99.16	10	373	2	355	3.2e-128	422.6	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
2918254107	205	71.29	5	204	10	153	3.0e-22	73.7	COG1776	Chemotaxis protein CheY-P-specific phosphatase CheC	203
2918254108	119	87.22	1	119	5	120	4.8e-20	66.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918254109	162	95.77	22	162	2	137	2.7e-21	70.4	COG1569	Predicted nucleic acid-binding protein, contains PIN domain	142
2918254111	191	85.1	3	191	29	205	2.2e-37	123.2	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2918254112	385	92.48	3	181	6	128	6.3e-31	101.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918254113	256	27.4	111	163	20	59	2.4e-06	12.1	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2918254113	256	42.47	186	254	69	130	2.4e-06	7.7	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2918254114	101	85.47	1	101	5	104	1.6e-17	58.1	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918254115	801	32.49	60	258	32	159	4.1e-48	9.5	COG0642	Signal transduction histidine kinase	336
2918254115	801	67.01	304	777	127	390	4.1e-48	153.9	COG0642	Signal transduction histidine kinase	336
2918254116	978	56	872	973	20	89	2.0e-08	28	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918254116	978	89.85	76	551	37	390	8.2e-76	249.3	COG0642	Signal transduction histidine kinase	336
2918254118	274	81.46	18	171	28	172	5.1e-07	22.5	COG1633	Rubrerythrin	176
2918254119	139	97.78	1	135	1	132	4.8e-36	118.3	COG0355	FoF1-type ATP synthase, epsilon subunit	135
2918254120	472	99.15	5	472	3	466	0.0e+00	790.8	COG0055	FoF1-type ATP synthase, beta subunit	468
2918254121	297	99.65	5	297	1	287	3.8e-105	346.4	COG0224	FoF1-type ATP synthase, gamma subunit	287
2918254122	509	99.21	1	509	1	500	0.0e+00	791.6	COG0056	FoF1-type ATP synthase, alpha subunit	504
2918254123	189	97.75	7	183	5	178	6.2e-51	167.4	COG0712	FoF1-type ATP synthase, delta subunit	178
2918254126	750	99.59	24	749	4	734	0.0e+00	755.1	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
2918254127	218	97.04	1	218	8	302	1.8e-68	224	COG0176	Transaldolase	239
2918254128	237	98.62	12	234	2	216	5.3e-36	118.9	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
2918254129	316	97.99	9	316	6	298	5.0e-69	227.6	COG4973	Site-specific recombinase XerC	299
2918254130	728	99.3	3	722	4	709	0.0e+00	624.2	COG0557	Exoribonuclease R	706
2918254131	537	76.23	129	473	59	369	2.6e-80	264.7	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
2918254132	55	92.16	3	53	5	51	6.0e-21	69.3	COG0267	Ribosomal protein L33	50
2918254133	294	97.67	7	294	2	295	3.8e-67	221.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918254134	142	98.55	2	142	3	138	2.6e-63	206.8	COG3565	Predicted dioxygenase of extradiol dioxygenase family	138
2918254135	525	99.4	21	522	4	501	0.0e+00	630.9	COG3845	ABC-type uncharacterized transport system, ATPase component	501
2918254136	332	94.62	1	331	7	340	3.0e-99	326.9	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
2918254137	211	94.71	1	203	8	204	7.8e-25	81.9	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918254138	218	92.79	5	207	6	198	7.0e-41	134.5	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2918254139	442	41.74	12	220	72	172	1.4e-06	22.7	COG2202	PAS domain	232
2918254139	442	50	235	436	54	180	9.8e-10	33.1	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2918254142	316	99.22	1	273	1	255	3.5e-47	156.4	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2918254143	170	89.25	1	165	16	181	1.6e-50	166	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918254144	227	71.07	1	175	1	140	1.1e-22	75.5	COG1988	Membrane-bound metal-dependent hydrolase YbcI, DUF457 family	190
2918254145	641	99.28	50	614	1	548	0.0e+00	669	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918254148	600	98	10	600	9	595	0.0e+00	595.8	COG1164	Oligoendopeptidase F	598
2918254149	126	86.11	3	125	7	130	3.0e-18	60.4	COG2703	Hemerythrin	144
2918254152	509	53.76	6	314	38	187	8.5e-09	30.1	COG0500	SAM-dependent methyltransferase	257
2918254153	127	94.79	20	115	2	92	2.2e-28	93	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
2918254154	235	90.61	5	232	9	230	4.2e-49	161.6	COG0704	Phosphate uptake regulator	240
2918254155	181	95.86	1	170	4	165	1.1e-62	205.6	COG2862	Uncharacterized membrane protein YqhA	169
2918254156	346	97.95	4	345	4	337	0.0e+00	494.6	COG1077	Actin-like ATPase involved in cell morphogenesis	342
2918254157	263	88.81	1	257	17	270	1.2e-52	173.3	COG1792	Cell shape-determining protein MreC	284
2918254158	170	86.83	8	169	13	157	4.4e-14	47.5	COG2891	Cell shape-determining protein MreD	167
2918254159	629	96.99	3	610	6	618	0.0e+00	539.8	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2918254160	339	98.82	1	337	3	336	0.0e+00	533.4	COG0059	Ketol-acid reductoisomerase	338
2918254161	169	96.91	5	169	3	159	4.0e-57	187.2	COG0440	Acetolactate synthase, small subunit	163
2918254162	587	99.46	5	571	2	553	0.0e+00	719.1	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918254163	387	83.55	1	387	72	452	3.4e-123	406.5	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918254164	326	90.91	3	314	3	282	6.6e-88	289.3	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
2918254165	297	98.58	79	289	3	211	9.0e-64	209.4	COG0560	Phosphoserine phosphatase	212
2918254166	136	89.58	2	135	2	130	2.4e-29	96.7	COG2703	Hemerythrin	144
2918254167	261	97.3	8	261	3	254	5.9e-98	322	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
2918254169	289	64.77	99	161	10	66	1.4e-04	15.9	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2918254170	214	94.95	7	210	7	194	1.5e-76	250.8	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
2918254171	238	98.69	10	238	4	229	3.5e-60	198.5	COG0830	Urease accessory protein UreF	229
2918254172	176	89.74	4	176	15	154	1.3e-36	119	COG2371	Urease accessory protein UreE	155
2918254173	281	93.66	1	280	8	258	9.3e-69	226.2	COG0796	Glutamate racemase	269
2918254174	569	99.82	2	569	2	569	0.0e+00	1070.2	COG0804	Urease alpha subunit	568
2918254176	101	95.28	1	101	1	101	1.4e-47	154.8	COG0832	Urease beta subunit	106
2918254177	100	100	1	100	1	100	1.6e-52	170.6	COG0831	Urease gamma subunit	100
2918254179	546	63.93	1	395	5	346	1.1e-54	180.3	COG1283	Na+/phosphate symporter	533
2918254180	302	97.43	24	300	5	269	5.9e-64	210.9	COG0829	Urease accessory protein UreH	269
2918254181	144	92.02	6	122	13	162	1.3e-27	91.6	COG0517	CBS domain	117
2918254182	246	97.63	19	243	3	208	6.6e-47	154.4	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918254183	221	98.58	4	216	2	209	7.7e-46	150.9	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918254184	190	96.94	6	182	3	192	3.7e-50	165	COG0693	Putative intracellular protease/amidase	188
2918254187	430	99.52	1	427	1	419	0.0e+00	600.4	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
2918254188	184	97.84	2	184	2	182	3.4e-62	204.1	COG0717	Deoxycytidine triphosphate deaminase	183
2918254189	144	64.81	8	131	50	154	8.9e-08	27.5	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918254191	660	98.36	1	656	2	540	0.0e+00	488.6	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2918254193	331	99.07	1	327	2	319	1.8e-89	295.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918254195	136	93.75	8	136	7	126	2.3e-27	90.1	COG3755	Uncharacterized conserved protein YecT, DUF1311 family	127
2918254196	135	15.07	7	35	3	24	9.2e-10	14.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918254196	135	36.3	31	115	92	144	9.2e-10	22	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918254197	404	91.44	19	390	33	406	5.3e-38	126.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918254198	337	96.93	2	314	8	323	4.0e-53	175	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2918254199	317	98.44	1	317	2	317	5.3e-63	208.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918254200	644	98.5	10	636	2	593	0.0e+00	609.8	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
2918254203	358	96.22	2	358	2	357	0.0e+00	535.2	COG0082	Chorismate synthase	369
2918254204	207	24.31	7	111	32	75	1.6e-03	3.3	COG5342	Invasion protein IalB, involved in pathogenesis	181
2918254204	207	26.52	133	191	133	180	1.6e-03	7.7	COG5342	Invasion protein IalB, involved in pathogenesis	181
2918254205	824	53.02	532	709	2	124	2.7e-26	86.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918254205	824	83.5	49	518	63	391	2.7e-77	255	COG0642	Signal transduction histidine kinase	336
2918254206	750	84.52	326	749	56	388	5.3e-72	238.3	COG0642	Signal transduction histidine kinase	336
2918254207	268	97.74	10	265	7	265	1.6e-74	245.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918254208	172	92.14	9	147	8	136	6.1e-50	162.7	COG1832	Predicted CoA-binding protein	140
2918254209	431	99.3	2	429	3	426	0.0e+00	635.9	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
2918254210	145	30.59	5	142	179	297	2.9e-03	11.2	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918254211	402	50.65	203	400	2	195	1.1e-27	33.6	COG0477	MFS family permease	338
2918254211	402	50.91	3	201	8	202	1.1e-27	64.6	COG0477	MFS family permease	338
2918254212	104	97.12	1	104	3	103	1.0e-32	106.8	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
2918254214	995	27.92	198	483	56	165	4.2e-56	12.3	COG0642	Signal transduction histidine kinase	336
2918254214	995	67.51	431	847	127	392	4.2e-56	185.9	COG0642	Signal transduction histidine kinase	336
2918254215	72	90.48	6	72	3	59	3.2e-10	34.2	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918254216	330	98.2	10	329	1	327	0.0e+00	441.6	COG1494	Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase or related protein	332
2918254217	432	98.2	4	328	4	331	2.4e-111	366.7	COG0460	Homoserine dehydrogenase	333
2918254218	424	98.48	7	401	5	394	1.0e-124	411.2	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918254219	584	99.31	109	562	3	433	0.0e+00	724.3	COG0422	Thiamine biosynthesis protein ThiC	432
2918254221	311	95.35	22	311	9	295	5.3e-40	132.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918254222	327	90.24	10	327	33	328	1.0e-49	163.7	COG0598	Mg2+ and Co2+ transporter CorA	322
2918254224	299	98.87	27	298	2	263	6.4e-105	344.7	COG0548	Acetylglutamate kinase	265
2918254226	423	94	6	417	5	380	7.3e-52	170.9	COG0475	Kef-type K+ transport system, membrane component KefB	397
2918254227	220	96.5	23	220	3	195	2.5e-67	220.9	COG0218	GTP-binding protein EngB required for normal cell division	200
2918254228	576	93.97	260	576	2	297	1.2e-102	338.2	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
2918254229	104	83.7	5	95	8	84	6.2e-34	110.2	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
2918254230	144	88.98	5	128	5	109	3.6e-24	79.7	COG0594	RNase P protein component	117
2918254231	44	100	1	44	1	44	2.4e-24	79.9	COG0230	Ribosomal protein L34	44
2918254232	130	94.26	1	118	7	121	3.3e-52	170.3	COG0335	Ribosomal protein L19	115
2918254233	270	95.49	11	261	3	235	1.2e-91	300.7	COG0336	tRNA G37 N-methylase TrmD	240
2918254234	185	93.68	1	168	8	170	1.6e-38	126.6	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
2918254235	117	95.56	2	99	1	86	6.2e-35	113.4	COG0228	Ribosomal protein S16	87
2918254236	455	97.57	1	452	1	441	0.0e+00	596.7	COG0541	Signal recognition particle GTPase	451
2918254238	451	44.62	140	267	95	206	1.3e-82	80.4	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918254238	451	61.35	279	450	65	218	1.3e-82	123.1	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918254238	451	62.95	8	187	82	239	1.3e-82	95.9	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918254241	436	5.22	37	63	50	68	1.7e-25	1.6	COG5330	Uncharacterized conserved protein, DUF2336 family	364
2918254241	436	71.7	66	400	49	309	1.7e-25	80.6	COG5330	Uncharacterized conserved protein, DUF2336 family	364
2918254242	582	71.07	17	237	68	239	2.2e-07	26	COG2202	PAS domain	232
2918254242	582	92.9	377	556	12	181	5.8e-47	153.7	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918254243	229	95.24	10	226	6	225	2.2e-36	120.6	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918254244	280	98.53	3	280	3	270	5.6e-95	312.7	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
2918254245	390	95.93	1	380	14	414	2.1e-98	324.8	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918254247	535	97.82	4	432	2	405	2.0e-117	387.3	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918254248	284	99.34	1	281	1	299	2.5e-49	163.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918254249	537	97.58	1	537	9	572	2.2e-100	332	COG0747	ABC-type transport system, periplasmic component	556
2918254250	388	98.28	20	370	2	344	0.0e+00	468.4	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
2918254252	184	91.94	8	184	9	179	4.0e-41	135.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918254253	231	98.61	4	231	2	214	2.5e-41	135.4	COG3806	Anti-sigma factor ChrR, cupin superfamily	216
2918254254	155	34.51	26	144	94	171	3.4e-07	23.9	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
2918254255	548	29.73	8	152	7	116	4.1e-65	16.5	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2918254255	548	52.43	274	515	169	362	4.1e-65	196.4	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2918254256	568	99.45	10	559	2	548	0.0e+00	734.6	COG0539	Ribosomal protein S1	541
2918254257	224	95.98	2	219	5	219	4.6e-64	209.7	COG0283	Cytidylate kinase	222
2918254258	445	98.14	4	442	9	430	0.0e+00	439.2	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
2918254259	129	99.22	1	128	1	128	3.2e-21	70.5	COG4530	Uncharacterized protein	129
2918254262	567	75.34	382	563	22	189	2.9e-27	90.8	COG1226	Voltage-gated potassium channel Kch	212
2918254262	567	97.5	1	393	3	392	8.0e-90	296	COG0475	Kef-type K+ transport system, membrane component KefB	397
2918254263	345	99.43	1	345	1	348	0.0e+00	443.4	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
2918254264	284	95.82	2	284	11	285	0.0e+00	455.9	COG4208	ABC-type sulfate transport system, permease component	287
2918254265	269	96.72	1	268	8	272	9.3e-105	344.1	COG0555	ABC-type sulfate transport system, permease component	274
2918254266	337	90.54	4	337	31	346	0.0e+00	543.8	COG1613	ABC-type sulfate transport system, periplasmic component	348
2918254268	150	89.33	1	149	2	135	4.4e-43	141.6	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918254269	210	92.31	1	210	16	255	1.6e-49	163.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918254270	279	58.33	25	269	6	159	4.0e-36	119.3	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918254271	716	87.29	243	711	53	423	2.9e-63	209	COG0840	Methyl-accepting chemotaxis protein	408
2918254272	169	84.54	1	169	29	192	4.4e-40	132	COG3963	Phospholipid N-methyltransferase	194
2918254273	443	75	3	335	30	305	6.9e-10	34.1	COG0457	Tetratricopeptide (TPR) repeat	291
2918254274	120	80.99	1	120	7	121	3.7e-51	167.4	COG1803	Methylglyoxal synthase	142
2918254275	721	99.13	4	719	4	574	0.0e+00	756.4	COG2225	Malate synthase	545
2918254276	212	94.83	4	174	2	166	6.7e-21	69.5	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2918254277	209	77.99	1	208	15	177	3.0e-17	57.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918254278	969	92.97	23	320	12	315	8.4e-82	269.2	COG0258	5'-3' exonuclease	310
2918254278	969	99.83	358	969	2	597	0.0e+00	748	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
2918254279	309	95.32	9	304	7	291	4.7e-29	95.6	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918254280	305	95.15	1	296	16	309	1.7e-82	271.6	COG3386	Sugar lactone lactonase YvrE	307
2918254281	280	53.89	1	211	2	174	3.7e-39	129.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918254282	480	98.54	5	478	2	473	0.0e+00	545.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918254283	249	98.28	2	238	2	229	3.0e-59	194.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918254285	564	86.68	206	548	47	365	5.7e-35	112.4	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2918254288	285	66.75	2	285	127	389	3.8e-52	172.8	COG0642	Signal transduction histidine kinase	336
2918254289	240	40	38	240	257	430	6.1e-61	200.9	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918254290	526	59.34	392	522	11	118	4.5e-07	23.8	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918254290	526	77.16	9	376	85	388	1.6e-53	177.1	COG0642	Signal transduction histidine kinase	336
2918254291	255	28.02	4	86	2	66	2.5e-34	18.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918254291	255	52.16	116	247	2	122	2.5e-34	93.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918254292	369	98.01	6	368	2	346	3.8e-91	300.4	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918254293	738	13.66	1	132	5	107	1.3e-108	49.1	COG0643	Chemotaxis protein histidine kinase CheA	716
2918254293	738	52.12	108	603	349	741	1.3e-108	309.6	COG0643	Chemotaxis protein histidine kinase CheA	716
2918254294	562	91.76	129	562	36	425	3.6e-74	245.4	COG0840	Methyl-accepting chemotaxis protein	408
2918254295	200	76.36	57	200	28	153	2.5e-14	47.7	COG0835	Chemotaxis signal transduction protein	165
2918254296	451	98.52	10	285	3	268	1.3e-67	222.4	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918254297	183	85.45	4	162	19	159	2.2e-16	54.3	COG0835	Chemotaxis signal transduction protein	165
2918254300	134	86.01	1	129	18	140	2.6e-27	90.2	COG5469	Predicted metal-binding protein	143
2918254301	1141	83.25	536	896	60	387	2.0e-69	228.5	COG0642	Signal transduction histidine kinase	336
2918254301	1141	91.52	18	480	12	421	1.5e-09	31.7	COG1457	Purine-cytosine permease or related protein	442
2918254301	1141	91.73	912	1040	7	128	1.0e-18	60.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918254302	316	96.68	5	314	3	206	4.8e-39	115.2	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918254303	138	96.97	11	131	1	128	1.1e-29	98	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918254304	817	9.17	12	84	5	71	0.0e+00	32.2	COG2217	Cation transport ATPase	713
2918254304	817	99.18	79	812	4	728	0.0e+00	874.5	COG2217	Cation transport ATPase	713
2918254306	220	94.74	17	219	4	201	4.5e-56	184.2	COG2860	Uncharacterized membrane protein YeiH	209
2918254307	420	92.62	20	393	4	342	4.1e-36	119.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918254308	692	81.41	231	685	78	423	7.6e-66	218	COG0840	Methyl-accepting chemotaxis protein	408
2918254309	253	82.91	93	245	23	153	4.7e-13	43.8	COG0639	Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family	155
2918254311	162	98.18	1	162	4	165	3.5e-57	187.9	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
2918254312	337	96.88	16	327	3	312	5.3e-114	375.4	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918254313	333	98.77	3	317	1	321	4.0e-129	424.8	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918254314	316	95.3	21	316	13	296	2.8e-100	329.7	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918254315	336	99.37	1	336	1	316	3.3e-126	415.7	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918254316	533	95.67	1	532	17	569	0.0e+00	456	COG0747	ABC-type transport system, periplasmic component	556
2918254317	319	96.68	6	305	6	296	1.5e-48	160.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918254318	286	97.67	1	281	5	255	2.1e-41	136	COG3394	Predicted glycoside hydrolase or deacetylase ChbG, UPF0249 family	257
2918254319	261	48.03	11	259	54	187	5.9e-11	37.6	COG0500	SAM-dependent methyltransferase	257
2918254320	134	41.01	69	134	13	69	1.8e-21	33.6	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
2918254320	134	44.6	2	72	11	72	1.8e-21	43	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
2918254321	548	97.83	30	548	4	543	5.0e-128	422.3	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918254323	262	19.35	1	48	15	50	1.9e-12	14.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918254323	262	31.72	46	137	120	178	1.9e-12	26.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918254323	262	90.98	128	253	7	127	3.0e-18	60.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918254324	288	98.26	1	288	5	286	1.8e-127	419.5	COG0788	Formyltetrahydrofolate hydrolase	287
2918254326	55	14.02	4	55	162	207	1.7e-03	12	COG0598	Mg2+ and Co2+ transporter CorA	322
2918254327	269	73.31	12	266	70	264	9.0e-64	210.1	COG0860	N-acetylmuramoyl-L-alanine amidase	231
2918254328	206	90.86	14	203	16	194	1.4e-30	101.4	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918254329	451	31.25	3	259	120	234	4.3e-05	8.4	COG0457	Tetratricopeptide (TPR) repeat	291
2918254329	451	45.65	228	445	7	174	4.3e-05	9.2	COG0457	Tetratricopeptide (TPR) repeat	291
2918254331	403	28.24	5	99	1	85	7.2e-75	89.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918254331	403	97.34	105	403	4	296	7.2e-75	163.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918254332	315	95.73	1	315	4	339	1.8e-54	180.1	COG0673	Predicted dehydrogenase	342
2918254335	291	98.21	15	291	3	277	1.8e-47	156.9	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2918254336	214	68.11	1	212	16	188	3.9e-35	116.7	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2918254337	326	96.68	41	325	2	292	2.7e-60	198.8	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918254338	575	96.69	14	569	14	539	6.8e-116	382.3	COG1178	ABC-type Fe3+ transport system, permease component	540
2918254339	153	92.41	8	151	6	151	1.2e-27	91.4	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918254340	314	91.91	2	305	24	307	1.6e-80	265.1	COG0010	Arginase family enzyme	305
2918254341	352	99.09	5	328	3	329	1.4e-103	341.3	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2918254342	1019	25.17	707	865	423	571	1.0e-56	44.4	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918254342	1019	75.68	2	478	7	454	1.0e-56	141.1	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918254343	595	98.91	1	550	5	550	0.0e+00	635.8	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918254344	644	96.37	1	627	8	564	8.3e-61	201.1	COG0747	ABC-type transport system, periplasmic component	556
2918254345	341	99.37	1	337	1	316	3.3e-84	277.6	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918254346	395	76.17	34	395	68	294	9.5e-87	285.3	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918254347	414	92	9	400	6	373	1.6e-110	363.9	COG4671	Predicted glycosyl transferase	400
2918254348	423	89.73	15	419	33	399	2.5e-36	120.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918254349	369	96.58	2	369	11	405	1.0e-27	92.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918254350	203	77.51	3	192	3	164	5.1e-34	112.4	COG0406	Broad specificity phosphatase PhoE	208
2918254351	391	95	1	391	11	390	1.2e-55	183.3	COG4671	Predicted glycosyl transferase	400
2918254352	264	52.99	47	253	103	244	1.3e-05	19	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918254353	391	100	1	391	1	394	0.0e+00	500.6	COG0183	Acetyl-CoA acetyltransferase	392
2918254354	455	98.45	18	455	7	452	0.0e+00	593	COG2031	Short chain fatty acids transporter	446
2918254355	218	95.11	1	217	7	220	7.4e-87	285.1	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
2918254356	220	97.73	1	219	3	217	2.7e-83	273.2	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
2918254357	468	96.79	4	468	8	459	0.0e+00	571	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918254358	624	42.86	192	272	49	84	2.3e-03	11.8	COG2770	HAMP domain	83
2918254358	624	62.69	318	622	143	389	1.5e-63	210.2	COG0642	Signal transduction histidine kinase	336
2918254359	564	75.76	122	556	78	399	6.0e-55	180.1	COG0840	Methyl-accepting chemotaxis protein	408
2918254360	618	98.62	6	614	5	574	0.0e+00	655.9	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918254361	299	98.58	4	283	4	281	7.5e-74	242.9	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918254363	216	97.16	1	212	2	206	1.7e-57	189	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918254364	187	28.07	92	179	80	111	1.1e-06	22	COG0607	Rhodanese-related sulfurtransferase	110
2918254366	315	26.01	226	313	191	261	1.4e-27	17.7	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2918254366	315	34.8	1	135	4	98	1.4e-27	71.8	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2918254367	258	92.98	2	247	9	233	2.0e-64	211.8	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
2918254369	372	95.53	9	350	14	355	2.6e-66	218.8	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2918254373	332	28.36	278	320	45	63	1.8e-04	3	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2918254373	332	29.85	131	156	45	64	1.8e-04	2.6	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2918254373	332	88.06	146	211	8	66	1.8e-04	7.6	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2918254374	150	88	2	143	2	133	1.3e-35	117.3	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918254375	494	99.54	40	492	2	433	0.0e+00	522.4	COG0719	Fe-S cluster assembly scaffold protein SufB	412
2918254376	250	96.03	1	249	3	244	8.7e-108	353.9	COG0396	Fe-S cluster assembly ATPase SufC	251
2918254377	451	71.89	107	441	108	419	3.1e-70	231.7	COG0719	Fe-S cluster assembly scaffold protein SufB	412
2918254378	427	99.27	15	426	2	407	0.0e+00	516.8	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
2918254379	157	90.73	3	156	4	140	1.3e-41	136.6	COG0822	NifU homolog involved in Fe-S cluster formation	150
2918254380	144	84.96	41	143	11	106	2.5e-35	115.1	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
2918254381	114	97.27	6	114	4	110	1.4e-38	125.9	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2918254382	237	94.57	17	233	10	218	1.4e-12	41.7	COG2755	Lysophospholipase L1 or related esterase	216
2918254384	405	87.32	13	404	21	378	9.9e-63	206.8	COG4645	Uncharacterized protein	410
2918254385	890	99.08	1	881	8	866	0.0e+00	900.5	COG0308	Aminopeptidase N	859
2918254386	126	87.5	1	126	13	131	8.5e-46	150.1	COG3474	Cytochrome c2	135
2918254387	224	97.26	1	146	1	142	2.1e-49	161.6	COG3427	Carbon monoxide dehydrogenase subunit G	146
2918254389	184	93.79	15	176	3	153	2.5e-47	155	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
2918254390	192	88.95	18	191	8	176	1.7e-51	169.2	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918254391	135	73.55	40	134	31	119	3.2e-08	28.4	COG1539	Dihydroneopterin aldolase	121
2918254393	122	92.48	1	122	5	127	3.3e-23	76.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918254394	1041	99.8	2	1016	2	1013	0.0e+00	1105.3	COG0841	Multidrug efflux pump subunit AcrB	1009
2918254395	379	95.64	9	375	13	385	1.7e-52	172.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918254397	283	44.01	7	269	4	161	1.3e-14	49.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918254398	208	89	11	208	17	194	2.0e-64	211.8	COG0740	ATP-dependent protease ClpP, protease subunit	200
2918254402	339	97.69	1	338	8	345	1.9e-110	363.9	COG2957	Agmatine/peptidylarginine deiminase	346
2918254403	277	95.88	1	269	11	266	4.4e-95	312.6	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918254404	313	94.44	17	313	12	283	6.0e-110	361.6	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918254405	386	98.87	19	386	3	351	0.0e+00	453.3	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918254406	365	98.41	1	365	4	375	4.0e-86	284.1	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918254407	425	94.17	1	424	25	444	1.6e-122	404	COG0174	Glutamine synthetase	443
2918254408	67	9.36	37	67	57	75	1.7e-03	5.1	COG4332	Uncharacterized protein	203
2918254408	67	12.32	2	39	58	82	1.7e-03	6	COG4332	Uncharacterized protein	203
2918254409	428	82.18	4	427	2	333	5.1e-48	159	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
2918254410	1268	99.79	1	1244	1	947	5.2e-112	360.4	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2918254412	343	96.97	76	335	4	259	4.0e-69	227.9	COG1192	Cellulose biosynthesis protein BcsQ	259
2918254413	306	84.85	34	304	5	228	4.3e-40	132.6	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918254414	191	98.82	23	191	1	167	4.8e-27	90	COG3663	G:T/U-mismatch repair DNA glycosylase	169
2918254415	560	27.64	12	158	7	163	3.0e-36	39.2	COG2303	Choline dehydrogenase or related flavoprotein	542
2918254415	560	58.63	130	557	228	560	3.0e-36	80.9	COG2303	Choline dehydrogenase or related flavoprotein	542
2918254416	148	63.98	6	145	66	184	3.9e-28	93.4	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918254417	250	94.93	1	250	1	262	3.8e-42	139.3	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2918254418	536	94.74	119	269	8	151	4.6e-63	205.4	COG5616	TolB amino-terminal domain (function unknown)	152
2918254419	235	96.62	1	233	3	231	1.1e-85	281.2	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918254420	253	98.82	7	252	3	253	6.4e-86	282.4	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918254421	342	95.67	15	328	9	317	2.7e-65	215.3	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918254422	297	97.01	9	297	5	296	7.0e-75	247	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918254423	390	96.17	17	376	2	353	9.4e-65	213.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918254424	269	94.72	17	266	15	265	1.1e-66	219.5	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918254425	512	95.25	2	508	17	557	2.9e-97	320.8	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918254426	187	96.15	24	179	3	152	4.8e-57	186.6	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918254427	279	97.9	1	277	2	281	1.1e-54	180.4	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2918254428	1004	95.21	838	982	4	142	6.2e-39	127	COG3427	Carbon monoxide dehydrogenase subunit G	146
2918254428	1004	99.19	16	811	5	743	0.0e+00	548.8	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918254429	297	78.79	152	277	21	124	2.8e-23	76.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918254430	843	99.38	28	839	3	798	0.0e+00	1177.6	COG1251	NAD(P)H-nitrite reductase, large subunit	793
2918254431	129	91.59	11	113	5	102	1.1e-24	80.9	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2918254432	912	82.54	855	912	3	54	4.1e-08	26.6	COG2906	Bacterioferritin-associated ferredoxin	63
2918254432	912	94.69	2	722	42	808	0.0e+00	548.7	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918254433	275	95.49	12	262	3	235	6.7e-84	275.9	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2918254435	368	95.1	3	367	2	370	4.3e-74	244.4	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
2918254436	384	95.19	1	384	13	388	4.8e-38	125.5	COG2814	Predicted arabinose efflux permease, MFS family	394
2918254438	408	98.36	10	384	4	363	5.7e-40	132	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918254440	475	12.9	330	474	345	417	5.4e-31	25.8	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918254440	475	47.35	3	308	7	274	5.4e-31	79.4	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918254441	390	90.91	8	372	6	335	5.6e-104	342.7	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918254442	512	30.04	279	512	256	425	9.6e-36	29.5	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918254442	512	40.11	10	251	5	231	9.6e-36	90	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918254443	263	95.65	195	263	3	68	1.1e-36	60.5	COG3585	Molybdopterin-binding protein	69
2918254443	263	97.1	123	191	1	67	1.1e-36	59.3	COG3585	Molybdopterin-binding protein	69
2918254443	263	99.24	1	131	1	130	2.2e-34	112.5	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
2918254444	270	97.06	36	269	7	237	9.0e-16	52.2	COG0528	Uridylate kinase	238
2918254445	277	96.64	41	272	8	237	3.6e-12	39.5	COG0528	Uridylate kinase	238
2918254447	250	93.97	5	237	10	227	4.1e-48	158.3	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918254448	334	69.69	9	334	6	251	7.5e-108	351.4	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918254449	434	97.09	13	434	5	371	5.2e-34	112.3	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918254450	308	95.14	24	307	6	279	6.2e-78	256.6	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918254451	282	94.38	6	278	5	256	7.0e-67	220	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918254452	253	100	1	235	1	230	8.3e-80	262.1	COG4126	Asp/Glu/hydantoin racemase	230
2918254453	289	71.6	10	137	37	152	4.8e-04	15.8	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918254454	191	90.86	1	176	15	183	7.1e-39	128.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918254455	325	93.81	1	324	12	314	2.5e-85	280.8	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918254456	805	94.09	3	805	21	768	1.9e-94	310.3	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918254457	1210	94.59	17	90	2	71	1.8e-13	43.2	COG3433	Aryl carrier domain	74
2918254457	1210	99.23	336	1002	6	648	0.0e+00	434.4	COG1020	Non-ribosomal peptide synthetase component F	642
2918254458	141	91.09	24	119	7	98	7.9e-17	56	COG1605	Chorismate mutase	101
2918254459	553	98.52	6	545	7	540	0.0e+00	723	COG1021	Non-ribosomal peptide synthetase component E (peptide arylation enzyme)	542
2918254460	411	86.35	21	411	56	422	5.0e-108	356.8	COG1169	Isochorismate synthase EntC	423
2918254461	1170	64.2	1083	1151	26	77	5.1e-03	11.1	COG0236	Acyl carrier protein	80
2918254461	1170	99.38	308	977	5	648	3.5e-123	406.8	COG1020	Non-ribosomal peptide synthetase component F	642
2918254462	1353	99.23	258	914	6	648	1.7e-122	405.1	COG1020	Non-ribosomal peptide synthetase component F	642
2918254463	1500	79.7	11	1100	5	950	0.0e+00	865.2	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2918254464	354	31.39	236	338	34	76	4.7e-10	10.9	COG1765	Uncharacterized OsmC-related protein	137
2918254464	354	37.96	49	118	29	80	4.7e-10	20.4	COG1765	Uncharacterized OsmC-related protein	137
2918254465	443	98.24	47	439	7	396	6.2e-120	395.1	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2918254467	257	90.16	8	246	3	222	5.7e-72	236.2	COG3208	Surfactin synthase thioesterase subunit	244
2918254468	1131	62.96	1049	1107	27	77	5.6e-03	10.8	COG0236	Acyl carrier protein	80
2918254468	1131	100	297	941	1	648	1.3e-125	414.9	COG1020	Non-ribosomal peptide synthetase component F	642
2918254469	2934	47.67	2515	2802	54	186	3.8e-09	28.7	COG0500	SAM-dependent methyltransferase	257
2918254469	2934	81.48	1358	1434	11	76	4.0e-07	22.2	COG0236	Acyl carrier protein	80
2918254469	2934	82.9	1	1256	6	989	0.0e+00	872.7	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2918254469	2934	99.69	1686	2352	3	648	3.6e-130	430.4	COG1020	Non-ribosomal peptide synthetase component F	642
2918254470	619	98.65	20	591	4	587	0.0e+00	453.5	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918254471	618	99.16	32	602	2	588	0.0e+00	462.3	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918254472	241	84.21	8	237	6	181	6.8e-11	37.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918254473	341	75.76	210	332	21	120	1.1e-23	77.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918254474	731	98.62	7	731	12	795	3.3e-61	202.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918254475	445	49.87	2	211	12	202	1.7e-08	20	COG0477	MFS family permease	338
2918254475	445	52.22	202	418	8	207	1.7e-08	14.5	COG0477	MFS family permease	338
2918254476	325	78.03	195	319	23	125	1.2e-25	83.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918254477	354	88.29	2	348	16	279	6.7e-64	209.9	COG1230	Co/Zn/Cd efflux system component	296
2918254478	266	98.49	1	263	5	265	1.5e-81	268.4	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918254479	382	96.99	5	382	7	393	3.4e-65	214	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918254480	367	91.23	1	354	7	370	6.6e-31	100.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918254481	392	96.74	1	389	12	397	2.0e-94	311.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918254482	390	99.75	1	389	1	393	0.0e+00	433.7	COG0183	Acetyl-CoA acetyltransferase	392
2918254483	307	86.02	13	304	5	287	3.8e-103	339.6	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918254484	278	98.11	19	275	6	265	2.7e-86	283.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918254485	309	98.37	65	308	3	244	5.0e-49	161	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918254486	664	11.07	383	429	6	39	1.5e-13	15.9	COG0492	Thioredoxin reductase	305
2918254486	664	45.6	466	649	109	248	1.5e-13	27.3	COG0492	Thioredoxin reductase	305
2918254486	664	97.52	3	364	3	356	2.8e-119	390.4	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918254487	227	65.55	16	223	9	145	3.4e-21	71	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918254488	258	96.64	1	235	8	266	1.7e-54	179.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918254489	344	99.4	8	333	1	329	4.1e-98	323.4	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918254490	405	95.08	21	383	4	351	5.3e-39	128.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918254491	41	7.44	1	29	139	165	1.5e-05	19.2	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918254493	258	13.95	42	116	168	220	5.0e-15	15.7	COG4249	Uncharacterized protein, contains caspase domain	380
2918254493	258	20.53	119	250	2	79	5.0e-15	33	COG4249	Uncharacterized protein, contains caspase domain	380
2918254494	501	33.81	310	390	74	120	9.8e-04	9.6	COG4768	Uncharacterized protein YoxC, contains an MCP-like domain	139
2918254494	501	40.91	7	147	141	239	3.7e-13	18.7	COG2202	PAS domain	232
2918254494	501	41.74	149	281	142	242	3.7e-13	23.8	COG2202	PAS domain	232
2918254494	501	51.08	398	500	49	119	9.8e-04	8.5	COG4768	Uncharacterized protein YoxC, contains an MCP-like domain	139
2918254495	199	53.08	18	145	2	70	9.5e-18	59.7	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918254496	309	70.91	44	143	20	97	3.0e-03	12.2	COG1544	Ribosome-associated translation inhibitor RaiA	110
2918254497	610	99.02	201	606	2	406	0.0e+00	506.5	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
2918254498	284	89.8	84	282	7	182	2.0e-78	256.6	COG1045	Serine acetyltransferase	194
2918254500	250	93.36	7	242	5	229	7.8e-47	154.3	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918254501	233	90.91	7	215	3	192	7.8e-39	128.1	COG0406	Broad specificity phosphatase PhoE	208
2918254502	253	98.51	1	248	1	264	8.3e-54	177.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918254503	230	94.91	9	229	7	211	1.2e-27	91.7	COG0778	Nitroreductase	207
2918254504	537	97.83	12	536	2	541	0.0e+00	535.6	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918254505	410	98.75	13	410	5	400	0.0e+00	446.2	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918254506	270	99.25	21	269	2	267	8.9e-76	249.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918254507	393	99.25	1	393	1	396	8.1e-96	316.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918254508	358	93.27	10	344	8	312	8.5e-60	197.1	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2918254509	389	98.73	4	388	6	394	8.7e-81	266.5	COG0183	Acetyl-CoA acetyltransferase	392
2918254510	402	98.09	8	378	6	364	8.9e-35	114.9	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918254511	388	98.94	5	388	4	378	3.1e-74	244.8	COG1454	Alcohol dehydrogenase, class IV	377
2918254512	215	92.24	1	215	12	225	9.2e-55	180.3	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918254513	147	92.47	6	143	2	136	1.5e-10	36.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918254514	293	96.01	6	291	9	297	5.2e-45	148.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918254515	230	93.1	11	230	9	224	2.4e-50	165.8	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918254516	259	98.35	8	258	3	240	1.9e-99	326.3	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918254517	283	91.67	33	283	16	224	1.4e-64	212.7	COG0765	ABC-type amino acid transport system, permease component	222
2918254518	257	88.34	2	250	29	278	1.0e-46	154.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918254523	134	62.9	2	130	70	186	1.4e-19	65.5	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918254524	224	94.09	1	219	3	225	5.3e-69	226.5	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
2918254525	205	85.87	1	204	3	233	4.6e-34	109.7	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
2918254526	182	92.43	1	178	6	176	8.1e-54	176.6	COG1268	Biotin transporter BioY	184
2918254527	481	95.6	2	481	19	561	1.1e-78	253.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918254528	394	98.73	2	393	5	393	2.0e-119	393.9	COG0183	Acetyl-CoA acetyltransferase	392
2918254529	415	43.86	208	406	12	179	1.6e-11	11.2	COG0477	MFS family permease	338
2918254529	415	72.32	18	287	3	279	1.6e-11	30.6	COG0477	MFS family permease	338
2918254533	746	91.62	172	598	30	390	5.0e-55	182.5	COG0642	Signal transduction histidine kinase	336
2918254534	1953	61.9	99	159	32	83	1.0e-122	16.2	COG2770	HAMP domain	83
2918254534	1953	74.44	1668	1802	19	117	1.7e-62	21.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918254534	1953	80.96	1079	1494	70	388	4.0e-72	235.9	COG0642	Signal transduction histidine kinase	336
2918254534	1953	89.29	815	895	2	76	1.0e-122	26.2	COG2770	HAMP domain	83
2918254534	1953	91.67	907	1009	2	78	1.0e-122	28.9	COG2770	HAMP domain	83
2918254534	1953	92.48	1546	1671	6	128	1.7e-62	69.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918254534	1953	92.48	1817	1946	5	127	1.7e-62	107.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918254534	1953	96.43	171	251	2	82	1.0e-122	46.7	COG2770	HAMP domain	83
2918254534	1953	96.43	263	343	2	82	1.0e-122	48.3	COG2770	HAMP domain	83
2918254534	1953	96.43	355	435	2	82	1.0e-122	46.9	COG2770	HAMP domain	83
2918254534	1953	96.43	447	527	2	82	1.0e-122	46.9	COG2770	HAMP domain	83
2918254534	1953	96.43	539	619	2	82	1.0e-122	46	COG2770	HAMP domain	83
2918254534	1953	96.43	631	711	2	82	1.0e-122	51	COG2770	HAMP domain	83
2918254534	1953	96.43	723	803	2	82	1.0e-122	52.3	COG2770	HAMP domain	83
2918254535	222	57.27	40	198	42	167	2.3e-10	34.7	COG4122	Predicted O-methyltransferase YrrM	219
2918254536	315	80.28	17	291	48	279	2.1e-88	290.8	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2918254537	241	92.45	9	217	9	204	6.3e-56	183.9	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
2918254538	222	97.47	6	222	5	235	8.2e-46	151	COG0412	Dienelactone hydrolase	236
2918254540	294	80.06	1	293	63	335	3.1e-92	304.3	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918254541	338	98.63	16	326	4	291	1.9e-98	324.1	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2918254543	344	98.83	1	342	1	339	2.6e-113	373.1	COG2008	Threonine aldolase	342
2918254545	524	97.01	1	514	11	561	1.5e-113	374.7	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918254546	374	92.89	2	372	28	393	1.3e-64	213.3	COG0183	Acetyl-CoA acetyltransferase	392
2918254547	186	75	117	185	14	73	5.6e-21	68.1	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918254548	443	97.95	9	434	7	388	1.6e-38	127.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918254549	607	95.69	8	582	12	566	0.0e+00	703.6	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2918254551	229	34.64	3	227	300	493	1.3e-20	68.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918254552	403	76.77	8	403	91	404	2.3e-24	81.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918254553	123	23.7	1	120	267	362	4.8e-04	13.6	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2918254557	1082	10.68	768	916	332	383	1.4e-11	4.8	COG1061	Superfamily II DNA or RNA helicase	442
2918254557	1082	11.29	600	750	254	308	1.4e-11	3.8	COG1061	Superfamily II DNA or RNA helicase	442
2918254557	1082	35.93	223	445	38	212	1.4e-11	26.2	COG1061	Superfamily II DNA or RNA helicase	442
2918254559	664	22.5	347	515	321	457	2.3e-55	23.8	COG2189	Adenine specific DNA methylase Mod	590
2918254559	664	40.56	5	270	16	262	2.3e-55	160.6	COG2189	Adenine specific DNA methylase Mod	590
2918254560	1017	98.27	1	1017	1	967	0.0e+00	859.4	COG3587	Restriction endonuclease	985
2918254561	189	57.01	1	189	135	325	1.0e-22	75.9	COG0582	Integrase	309
2918254565	417	75	10	89	23	94	1.2e-03	13.2	COG4004	Uncharacterized protein	96
2918254565	417	91.04	91	416	22	326	9.2e-15	50	COG0582	Integrase	309
2918254568	596	57.07	31	591	90	299	3.1e-10	26.2	COG0457	Tetratricopeptide (TPR) repeat	291
2918254569	357	78.89	27	353	27	310	4.2e-68	224.4	COG3405	Endo-1,4-beta-D-glucanase Y	360
2918254571	708	87.72	54	536	8	450	1.3e-72	239.6	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2918254572	264	78.2	76	253	46	210	3.8e-28	92.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918254573	296	98.4	6	296	2	309	1.2e-45	150.6	COG0679	Predicted permease	311
2918254574	160	93.01	1	153	5	137	5.3e-27	88.6	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2918254575	437	98.31	12	437	2	409	3.9e-59	195.2	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
2918254576	423	93.24	2	423	26	425	3.1e-112	369.7	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
2918254578	629	82.49	23	191	11	156	1.0e-32	107.8	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918254578	629	98.15	253	628	3	374	1.8e-99	328.1	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918254579	342	97.89	6	340	5	329	6.4e-91	299.6	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918254580	369	97.25	28	368	2	319	9.5e-49	160.6	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918254581	261	77.27	128	254	20	121	9.7e-25	81.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918254588	167	18.32	25	141	51	148	9.3e-04	12.9	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918254592	199	90.71	7	193	6	132	8.3e-20	65.4	COG5005	Mu-like prophage protein gpG	140
2918254593	141	96.4	1	141	2	135	1.0e-25	85	COG4387	Mu-like prophage protein gp36	139
2918254595	299	99.03	1	298	4	308	1.6e-86	285.1	COG4397	Mu-like prophage major head subunit gpT	308
2918254597	397	91.6	29	392	24	350	6.1e-27	88.7	COG4388	Mu-like prophage I protein	357
2918254600	255	84.49	5	255	19	274	2.0e-40	130	COG0863	DNA modification methylase	302
2918254601	530	93.42	20	525	28	510	7.3e-95	313	COG4383	Mu-like prophage protein gp29	517
2918254602	534	91.94	21	527	14	481	0.0e+00	467	COG4373	Mu-like prophage FluMu protein gp28	509
2918254606	71	33.33	5	71	78	117	1.8e-10	36.3	COG1734	RNA polymerase-binding transcription factor DksA	120
2918254619	178	97.65	4	176	3	168	6.0e-52	170.4	COG4396	Mu-like prophage host-nuclease inhibitor protein Gam	170
2918254626	656	74.3	153	395	63	273	3.9e-08	26	COG2801	Transposase InsO and inactivated derivatives	232
2918254628	183	54	15	84	40	93	8.0e-05	16.8	COG3636	DNA-binding prophage protein	100
2918254629	92	8.8	11	80	289	327	4.6e-04	13.9	COG1030	Membrane-bound serine protease (ClpP class)	436
2918254631	249	97.56	2	249	5	244	2.8e-88	290.3	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2918254632	236	96.76	14	236	5	213	4.2e-26	86.2	COG0778	Nitroreductase	207
2918254633	250	94.98	1	243	7	252	8.3e-18	59.2	COG0730	Uncharacterized membrane protein YfcA	258
2918254634	685	95.68	10	305	3	268	1.0e-44	145.7	COG0388	Predicted amidohydrolase	274
2918254634	685	99.27	341	661	2	273	1.2e-78	258.6	COG0171	NH3-dependent NAD+ synthetase	268
2918254635	892	59.46	316	881	251	621	3.1e-83	272	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918254636	397	98.53	24	390	3	337	1.1e-39	131.4	COG0859	ADP-heptose:LPS heptosyltransferase	334
2918254638	283	94.68	1	282	3	269	9.6e-81	265.3	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2918254639	249	92.67	13	239	10	224	9.0e-45	147.4	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918254640	433	98.91	29	402	2	363	1.1e-40	134.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918254641	279	92.83	10	267	5	250	6.8e-69	226.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918254642	373	99.45	4	371	3	366	7.8e-113	372	COG1062	Zn-dependent alcohol dehydrogenase	366
2918254643	274	16.72	2	64	13	62	1.2e-14	1.6	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
2918254643	274	40.47	69	235	103	223	1.2e-14	45.6	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
2918254644	392	96.99	3	379	10	396	3.3e-90	297.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918254645	498	96.48	1	494	13	560	6.6e-102	336.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918254646	296	95.47	21	296	9	282	2.3e-57	189.2	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2918254647	231	62.76	8	231	68	217	6.8e-18	60	COG3828	Type 1 glutamine amidotransferase (GATase1)-like domain	239
2918254648	257	97.76	1	243	5	266	1.4e-67	222.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918254649	262	98.88	3	259	3	267	1.7e-64	212.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918254650	185	68.06	8	175	28	157	1.3e-08	29.7	COG5553	Predicted metal-dependent enzyme of the double-stranded beta helix superfamily	191
2918254651	268	96.4	1	267	7	274	1.1e-21	72.2	COG1082	Sugar phosphate isomerase/epimerase	274
2918254652	269	98.51	7	251	4	267	3.2e-55	182.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918254653	325	97.31	1	325	4	329	8.0e-40	131.8	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918254654	345	71.71	8	332	54	271	5.3e-27	89.4	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2918254655	504	93.02	256	504	12	251	2.8e-95	164.2	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918254655	504	94.19	1	251	12	254	2.8e-95	155.6	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918254656	297	96.81	24	277	6	248	3.6e-84	276.7	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918254657	314	97.34	1	300	1	293	1.2e-57	190.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918254658	186	90.32	1	176	12	179	2.0e-38	126.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918254659	349	18.58	2	85	14	73	4.1e-76	37.3	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918254659	349	76.78	85	348	74	321	4.1e-76	219.5	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918254660	827	96.6	8	827	28	795	2.9e-123	402.7	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918254662	515	91.87	1	402	5	411	2.2e-40	133.7	COG3182	Uncharacterized iron-regulated membrane protein	442
2918254667	406	98.74	11	402	6	396	0.0e+00	495.4	COG3328	Transposase (or an inactivated derivative)	379
2918254669	164	51.57	1	148	137	284	1.1e-27	92	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2918254670	548	71.93	275	374	18	99	1.1e-30	22.6	COG0607	Rhodanese-related sulfurtransferase	110
2918254670	548	85.09	14	115	11	107	1.1e-30	25	COG0607	Rhodanese-related sulfurtransferase	110
2918254670	548	85.09	137	244	13	109	1.1e-30	34.2	COG0607	Rhodanese-related sulfurtransferase	110
2918254670	548	85.96	393	495	16	113	1.1e-30	13.8	COG0607	Rhodanese-related sulfurtransferase	110
2918254671	388	95.24	1	382	1	380	4.1e-56	185.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918254672	501	89.79	3	498	47	565	7.8e-108	356.3	COG0747	ABC-type transport system, periplasmic component	556
2918254673	371	99.2	1	367	1	370	3.4e-94	310.3	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918254674	333	98.11	7	333	4	315	6.7e-112	368.6	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918254675	310	91.61	18	309	24	296	2.0e-93	307.2	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918254676	345	98.77	4	323	1	321	4.6e-117	385.2	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918254677	312	96.88	1	302	2	311	1.4e-113	374	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918254678	313	97.76	8	262	2	263	2.2e-56	185.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918254679	400	98.48	6	398	2	389	2.3e-78	258.6	COG0183	Acetyl-CoA acetyltransferase	392
2918254680	479	81.87	1	326	2	317	1.7e-55	183	COG3425	3-hydroxy-3-methylglutaryl CoA synthase	377
2918254680	479	86.52	333	473	18	139	2.8e-18	60.2	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
2918254681	153	61.64	2	148	32	129	8.0e-13	41.8	COG2030	Acyl dehydratase	159
2918254682	392	99	1	382	1	395	3.2e-91	301	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918254683	73	46.94	1	72	78	146	2.4e-19	65.3	COG0511	Biotin carboxyl carrier protein	140
2918254684	449	68.73	1	449	1	444	0.0e+00	561	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918254685	512	95.06	1	510	13	512	0.0e+00	483.1	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2918254686	530	73.85	6	529	3	420	8.3e-32	100	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918254687	525	95.95	7	523	17	561	2.8e-97	321	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918254688	154	89.36	6	148	14	139	5.8e-27	88.8	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918254689	503	98.46	39	497	2	450	4.1e-96	317.1	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918254690	527	95.33	4	527	8	558	4.0e-105	347.5	COG0747	ABC-type transport system, periplasmic component	556
2918254691	551	97.18	1	544	9	560	7.4e-101	332.8	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918254692	306	99.69	1	306	1	317	4.9e-105	346.1	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918254693	281	88.59	2	279	25	288	7.1e-98	321.8	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918254694	326	99.38	4	322	1	323	9.0e-119	390.9	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918254695	334	95.31	12	319	5	309	8.4e-103	338.6	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918254696	387	92.48	6	382	15	383	4.2e-48	158.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918254697	134	75.47	3	134	30	149	4.7e-24	79.1	COG2030	Acyl dehydratase	159
2918254699	252	98.88	11	248	2	266	5.9e-54	178	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918254700	242	87.55	1	241	6	237	5.6e-62	204.1	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918254701	480	91.48	34	479	11	418	1.3e-47	157.6	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2918254702	326	97.81	5	325	5	316	3.8e-80	263.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918254703	563	48.25	279	369	7	61	3.1e-44	25.2	COG0607	Rhodanese-related sulfurtransferase	110
2918254703	563	90.35	19	126	8	110	3.1e-44	32.7	COG0607	Rhodanese-related sulfurtransferase	110
2918254703	563	92.11	396	498	7	111	3.1e-44	34.5	COG0607	Rhodanese-related sulfurtransferase	110
2918254703	563	92.98	145	251	8	113	3.1e-44	49	COG0607	Rhodanese-related sulfurtransferase	110
2918254704	517	48.68	86	335	63	210	3.1e-15	50.6	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2918254705	388	94.74	1	382	1	378	3.5e-65	215.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918254707	499	99.01	1	499	1	499	0.0e+00	672.5	COG3333	TctA family transporter	504
2918254708	477	92.54	15	461	13	434	4.5e-74	244.2	COG2079	2-methylcitrate dehydratase PrpD	453
2918254709	263	87.5	18	238	5	200	7.1e-46	151.2	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2918254710	534	95.5	19	526	5	556	1.4e-91	302.6	COG0747	ABC-type transport system, periplasmic component	556
2918254711	451	98.25	13	422	7	343	3.0e-94	310.5	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918254712	334	98.01	27	329	2	296	8.5e-65	214	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918254713	474	98.32	1	467	1	469	2.1e-112	370.8	COG4529	Uncharacterized NAD(P)/FAD-binding protein YdhS	474
2918254715	335	94.03	1	334	7	321	1.8e-28	94.3	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918254716	199	92.09	5	199	4	201	1.2e-52	173.6	COG0625	Glutathione S-transferase	211
2918254717	307	97.91	10	291	4	284	2.3e-80	264.8	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2918254718	398	47.78	219	397	8	190	3.0e-11	16.6	COG0477	MFS family permease	338
2918254718	398	52.22	11	219	3	202	3.0e-11	27.7	COG0477	MFS family permease	338
2918254719	287	96.81	21	271	3	245	1.5e-91	301	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918254720	549	93.41	295	549	15	255	4.8e-122	195.1	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918254720	549	95.74	28	283	10	256	4.8e-122	212.2	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918254721	358	83.58	1	335	51	330	1.7e-41	136.3	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918254723	315	94.93	1	315	12	329	1.2e-64	213.4	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918254724	286	97.29	27	283	5	255	3.2e-91	299.8	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918254725	266	93.23	15	260	12	245	3.3e-96	316.1	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918254726	302	94.77	25	301	5	276	9.5e-53	173.9	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2918254727	275	95.18	13	274	5	241	2.1e-37	123.4	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
2918254728	686	99.71	1	686	1	677	0.0e+00	655.7	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2918254729	599	97.88	16	582	2	554	0.0e+00	521.6	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
2918254730	352	84.92	1	332	5	325	4.3e-27	89.6	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918254731	362	98.58	4	358	5	352	5.1e-115	379	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918254732	289	94.1	3	288	11	281	5.4e-69	227.3	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918254733	268	92.88	5	263	13	260	4.4e-69	227.2	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918254734	274	99.19	16	261	2	245	3.0e-45	148.7	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918254735	257	95.62	2	251	7	246	2.6e-80	264.1	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918254736	257	93.41	5	257	14	254	3.5e-72	237.5	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918254737	337	94.03	1	333	8	322	1.7e-26	87.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918254738	425	89.02	1	420	8	445	1.1e-38	127.6	COG0531	Amino acid transporter	466
2918254740	440	97.96	14	424	8	343	1.7e-86	285	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918254741	341	87.38	53	318	2	264	4.0e-27	89.9	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918254742	377	90.37	1	373	4	322	4.8e-109	359.4	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918254743	597	95.59	17	576	8	527	1.3e-86	285.7	COG1178	ABC-type Fe3+ transport system, permease component	540
2918254744	496	90.81	51	489	7	411	1.6e-42	140.8	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2918254745	322	97.34	3	298	2	294	2.3e-72	238.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918254746	369	91.34	2	366	25	330	9.8e-45	147.8	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918254748	507	98.41	7	507	6	501	0.0e+00	656.5	COG3333	TctA family transporter	504
2918254749	332	97.81	11	329	6	317	1.5e-77	255.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918254750	355	32.8	14	149	122	182	3.6e-31	16.2	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918254750	355	95.7	171	355	5	182	3.6e-31	92.4	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918254751	478	94.84	37	477	9	431	4.9e-59	195.2	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2918254752	242	99.16	3	238	2	236	6.6e-88	288.5	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918254753	309	98.82	5	273	3	253	2.8e-91	299.9	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918254754	612	95.68	331	612	9	296	4.9e-104	98.7	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918254754	612	97.34	6	295	6	298	4.9e-104	250.3	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918254755	399	93.17	21	394	8	348	5.5e-74	243.9	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918254756	395	95.63	27	393	6	355	2.1e-70	232.1	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918254757	257	97.61	1	245	4	248	1.4e-88	291.2	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918254758	278	96.12	18	275	9	256	1.1e-73	242.4	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918254759	329	93.73	3	322	4	317	2.9e-52	172.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918254760	680	70.66	20	375	130	459	2.7e-117	386.8	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918254760	680	91.04	355	680	18	322	1.9e-55	182.9	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918254761	284	80.92	3	284	57	302	3.5e-33	110.1	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2918254762	376	97.38	6	353	7	340	3.4e-79	261.1	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918254763	392	94.24	6	388	22	397	1.2e-54	180.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918254765	284	96.81	21	278	6	248	2.3e-88	290.4	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918254766	276	95.35	16	276	10	255	4.6e-75	247	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918254767	360	97.31	18	352	9	333	8.7e-62	203.7	COG4521	ABC-type taurine transport system, periplasmic component	334
2918254768	527	95.5	4	521	11	562	1.0e-107	356	COG0747	ABC-type transport system, periplasmic component	556
2918254769	328	98.11	6	328	5	316	1.3e-105	347.9	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918254770	312	91.61	15	310	24	296	7.6e-88	288.8	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918254771	532	94.02	2	532	3	521	0.0e+00	647.5	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918254772	442	95.34	14	417	17	343	3.1e-97	320.3	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918254773	418	95.19	19	418	13	388	1.4e-28	94.2	COG2814	Predicted arabinose efflux permease, MFS family	394
2918254774	316	99.34	1	301	1	299	1.5e-52	173.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918254778	1744	52.5	104	296	18	122	1.1e-03	12.3	COG2263	Predicted RNA methylase	198
2918254780	705	94.7	8	336	4	253	1.9e-26	87.6	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918254782	315	94.62	6	314	7	305	5.8e-124	407.8	COG4227	Antirestriction protein ArdC	316
2918254785	344	83.19	1	213	1	188	9.2e-25	82	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2918254789	514	97.98	1	339	8	346	0.0e+00	438.4	COG1171	Threonine dehydratase	347
2918254790	330	91.46	13	330	29	328	6.5e-76	249.8	COG0598	Mg2+ and Co2+ transporter CorA	322
2918254792	363	23.78	10	116	27	94	5.9e-23	9.7	COG1652	Nucleoid-associated protein YgaU, contains BON and LysM domains	269
2918254792	363	42.66	117	363	159	280	5.9e-23	70.4	COG1652	Nucleoid-associated protein YgaU, contains BON and LysM domains	269
2918254793	286	37.8	1	88	39	100	7.5e-22	20.2	COG2010	Cytochrome c, mono- and diheme variants	150
2918254793	286	99.39	107	282	1	163	7.5e-22	55.1	COG2010	Cytochrome c, mono- and diheme variants	150
2918254794	158	96.6	7	157	6	147	9.9e-22	72.3	COG3909	Cytochrome c556	147
2918254795	194	87.8	1	191	16	195	9.7e-61	199.5	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2918254796	501	99.77	24	495	1	435	0.0e+00	489.1	COG0305	Replicative DNA helicase	435
2918254797	370	99.18	6	369	3	363	6.6e-111	365.3	COG0787	Alanine racemase	360
2918254798	258	94.76	1	258	12	264	3.6e-89	293.2	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2918254799	261	95.44	4	260	7	257	1.8e-98	323.5	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
2918254800	211	87.2	4	210	25	208	8.2e-60	196.2	COG0177	Endonuclease III	211
2918254801	285	57.03	15	269	125	347	7.1e-36	118.3	COG4963	Flp pilus assembly protein, ATPase CpaE	366
2918254803	699	96.94	1	699	8	672	8.0e-84	276.8	COG1289	Uncharacterized membrane protein YccC	674
2918254804	322	92.05	4	303	15	338	1.1e-85	280.7	COG1566	Multidrug resistance efflux pump	352
2918254805	150	94.74	17	145	4	129	7.9e-24	78.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918254806	339	98.5	8	339	4	332	2.3e-79	261.8	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918254807	67	63.49	13	67	24	63	3.9e-15	50.5	COG4256	Hemin uptake protein HemP	63
2918254808	66	93.15	1	66	4	71	5.5e-18	60	COG2608	Copper chaperone CopZ	71
2918254809	423	46.48	231	419	13	190	2.8e-34	6	COG0477	MFS family permease	338
2918254809	423	74.93	15	278	8	294	2.8e-34	110.5	COG0477	MFS family permease	338
2918254810	179	94.32	8	179	8	173	2.7e-75	246.5	COG0290	Translation initiation factor IF-3	176
2918254812	463	98.22	1	462	5	445	6.2e-105	346	COG2610	H+/gluconate symporter or related permease	442
2918254813	219	98.18	1	218	1	216	2.2e-78	257	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
2918254814	217	95.56	1	216	7	221	2.0e-86	283.6	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
2918254815	262	98.88	2	261	3	267	7.2e-67	220.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918254816	390	96.71	1	384	11	392	1.1e-120	397.5	COG2814	Predicted arabinose efflux permease, MFS family	394
2918254817	458	96.71	1	458	6	446	3.4e-103	340.6	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918254818	429	96.14	2	428	17	439	2.5e-122	403.1	COG1257	Hydroxymethylglutaryl-CoA reductase	436
2918254819	414	97.54	20	390	7	363	4.2e-34	112.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918254821	92	22.19	2	82	221	293	3.0e-03	11.2	COG1087	UDP-glucose 4-epimerase	329
2918254822	288	55.35	142	288	69	156	8.0e-21	61.2	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918254822	288	78.62	1	157	3	127	8.0e-21	13.2	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918254823	520	90.8	24	345	20	325	2.2e-92	303.8	COG2187	Aminoglycoside phosphotransferase family enzyme	337
2918254823	520	92.35	347	519	2	158	1.6e-40	133.6	COG0645	Predicted kinase	170
2918254825	183	53.91	30	139	27	88	1.4e-03	13.2	COG5442	Flagellar biosynthesis regulator FlaF	115
2918254826	312	97.34	16	301	5	297	1.5e-47	156.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918254827	900	32.69	543	604	34	67	1.4e-01	2.9	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2918254827	900	34.62	658	713	4	39	1.4e-01	6	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2918254827	900	52.88	720	808	14	68	1.4e-01	6.1	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2918254828	153	31.58	70	135	78	131	3.0e-08	10.3	COG5592	Hemerythrin superfamily protein	171
2918254828	153	38.6	1	73	69	134	3.0e-08	18.5	COG5592	Hemerythrin superfamily protein	171
2918254829	387	96.04	116	386	2	268	3.6e-89	293.1	COG0294	Dihydropteroate synthase	274
2918254830	454	96.86	1	451	11	473	0.0e+00	437.2	COG1109	Phosphomannomutase	464
2918254831	266	97.72	1	263	5	261	2.5e-97	319.8	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
2918254832	277	97.86	2	277	4	277	3.4e-108	355.6	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
2918254833	556	96.15	9	534	6	505	0.0e+00	547.6	COG0029	Aspartate oxidase	518
2918254834	350	95.69	27	349	13	323	1.5e-121	400	COG0379	Quinolinate synthase	324
2918254836	329	92.35	1	328	16	341	8.2e-77	253.2	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
2918254837	408	45.95	213	407	9	184	3.6e-33	8.6	COG0477	MFS family permease	338
2918254837	408	71.02	15	245	4	275	3.6e-33	104.2	COG0477	MFS family permease	338
2918254838	340	96.42	1	339	6	328	9.2e-43	141.4	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918254839	101	95.58	4	101	5	112	4.5e-11	34	COG1416	Intracellular sulfur oxidation protein, DsrE/DsrF family	112
2918254840	326	78.99	2	300	25	227	1.3e-10	32.5	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918254841	217	93.29	31	194	7	159	2.1e-50	165	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
2918254843	257	69.96	26	231	23	178	6.7e-39	128	COG2091	Phosphopantetheinyl transferase	223
2918254844	326	98.91	17	300	4	275	1.7e-82	271.3	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
2918254845	319	90.8	7	317	16	311	3.1e-82	270.5	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918254846	266	90.09	18	239	18	226	4.8e-30	99.8	COG0671	Membrane-associated phospholipid phosphatase	232
2918254851	329	97.67	3	307	1	294	8.4e-48	158.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918254852	390	89.81	13	385	31	365	7.6e-57	187.2	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918254854	182	45.67	41	169	37	131	3.0e-06	19.9	COG0288	Carbonic anhydrase	207
2918254855	467	98.46	11	461	3	451	6.6e-89	293.3	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918254856	232	98.71	2	231	2	230	6.9e-71	232.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918254857	264	64.94	31	263	67	229	2.7e-25	83.4	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
2918254858	286	12.09	219	279	365	415	3.3e-09	16.5	COG4223	Uncharacterized conserved protein	422
2918254858	286	25.12	2	187	217	322	3.3e-09	19.8	COG4223	Uncharacterized conserved protein	422
2918254859	511	65.54	266	511	89	263	3.9e-11	36.9	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2918254859	511	69.61	6	253	7	219	6.7e-40	131.8	COG1131	ABC-type multidrug transport system, ATPase component	293
2918254864	137	90.78	8	137	3	130	5.3e-52	169.9	COG0229	Peptide methionine sulfoxide reductase MsrB	140
2918254865	678	65.16	186	677	218	649	5.5e-114	376	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918254866	256	93.36	10	250	12	208	6.0e-41	134.6	COG0177	Endonuclease III	211
2918254867	601	88.72	477	601	6	123	2.9e-16	52.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918254867	601	91.12	59	464	33	391	2.0e-57	190.4	COG0642	Signal transduction histidine kinase	336
2918254868	390	98.16	13	387	8	380	1.1e-88	292.2	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
2918254869	129	96.55	1	113	3	114	4.3e-39	127.6	COG3564	Uncharacterized conserved protein, DUF779 family	116
2918254870	506	99.37	19	501	2	477	0.0e+00	582.9	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918254871	206	89.22	13	201	10	191	1.1e-32	107.5	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
2918254873	971	99.75	32	971	2	809	0.0e+00	590.8	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918254874	211	74.15	1	193	11	162	6.9e-45	147.4	COG0437	Fe-S-cluster-containing dehydrogenase component	203
2918254875	330	94.04	112	330	4	208	1.8e-52	172.5	COG2864	Cytochrome b subunit of formate dehydrogenase	218
2918254876	397	34.26	116	227	83	168	3.3e-73	53	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918254876	397	39.04	22	135	101	198	3.3e-73	74.4	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918254876	397	76.1	139	396	51	241	3.3e-73	139.4	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918254878	229	95.37	21	224	2	207	4.9e-39	129	COG0778	Nitroreductase	207
2918254879	442	96.47	8	442	2	438	0.0e+00	481.4	COG1797	Cobyrinic acid a,c-diamide synthase	451
2918254880	261	98.36	15	258	3	242	5.3e-88	289.5	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2918254881	359	96.19	1	358	10	362	1.8e-105	347.4	COG1903	Cobalamin biosynthesis protein CbiD	367
2918254882	253	98.04	1	253	3	252	6.1e-105	344.6	COG2875	Precorrin-4 methylase	254
2918254883	144	36.16	1	125	203	317	4.7e-18	60.1	COG2073	Cobalamin biosynthesis protein CbiG	298
2918254884	411	98.93	228	411	2	186	2.4e-68	223.7	COG2242	Precorrin-6B methylase 2	187
2918254884	411	99.05	13	220	1	208	3.9e-58	190.7	COG2241	Precorrin-6B methylase 1	210
2918254885	250	96.89	2	249	4	252	1.8e-74	244.9	COG2099	Precorrin-6x reductase	257
2918254886	252	98	1	252	1	245	5.5e-92	302.4	COG1010	Precorrin-3B methylase	249
2918254887	255	98.3	8	246	2	232	5.3e-73	240.1	COG2243	Precorrin-2 methylase	234
2918254888	212	96.21	4	212	4	206	1.9e-74	244.4	COG2082	Precorrin isomerase	210
2918254889	451	77.63	15	439	57	455	7.7e-55	180.7	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2918254890	1141	30.56	694	1141	828	1261	0.0e+00	520.1	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
2918254890	1141	51.13	10	700	16	741	0.0e+00	547.5	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
2918254891	349	96.93	12	348	1	316	9.5e-93	305.8	COG0523	GTPase, G3E family	323
2918254892	250	99.17	1	247	1	238	5.9e-63	207.2	COG5446	Uncharacterized membrane protein, predicted cobalt tansporter CbtA	233
2918254895	251	99.21	2	248	3	254	2.6e-87	287	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918254896	245	99.58	14	245	2	237	4.0e-87	285.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918254897	400	97.81	13	380	6	363	2.0e-48	159.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918254899	136	26.79	1	116	306	417	1.9e-32	107.1	COG1004	UDP-glucose 6-dehydrogenase	414
2918254900	466	95.4	4	455	15	470	3.7e-122	403	COG1109	Phosphomannomutase	464
2918254901	360	84.1	18	339	3	240	4.0e-14	46.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918254902	734	16.24	200	358	78	146	9.3e-54	30.2	COG0840	Methyl-accepting chemotaxis protein	408
2918254902	734	66.12	421	730	143	423	9.3e-54	148.4	COG0840	Methyl-accepting chemotaxis protein	408
2918254903	235	98.71	3	231	2	230	7.8e-68	222.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918254904	246	99.17	4	244	2	241	1.7e-113	372.4	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918254905	382	90.35	135	380	21	226	8.1e-66	216	COG0765	ABC-type amino acid transport system, permease component	222
2918254906	385	95.97	1	385	17	397	0.0e+00	491	COG4597	ABC-type amino acid transport system, permease component	397
2918254907	343	89.75	2	267	7	260	1.3e-43	143.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918254908	178	93.01	1	175	9	181	1.4e-40	133.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918254910	146	86.49	6	145	6	133	9.0e-09	29.8	COG5612	Uncharacterized membrane protein	148
2918254911	799	98.59	1	797	9	779	0.0e+00	1060.5	COG2183	Transcriptional accessory protein Tex/SPT6	780
2918254912	212	96.63	2	208	6	206	2.0e-40	132.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918254917	212	45.81	50	210	109	201	3.2e-05	18.2	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2918254918	105	97.22	1	105	1	105	6.2e-40	130.5	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
2918254919	410	95.97	32	410	14	370	2.4e-88	291.2	COG2021	Homoserine acetyltransferase	368
2918254921	521	43.08	270	516	4	168	6.0e-34	13.2	COG0477	MFS family permease	338
2918254921	521	88.77	19	304	4	343	6.0e-34	100.2	COG0477	MFS family permease	338
2918254922	369	95.45	1	357	9	344	2.0e-113	373.1	COG1566	Multidrug resistance efflux pump	352
2918254923	210	92.82	4	208	13	206	7.7e-27	90	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918254924	397	92.9	207	387	13	182	5.6e-54	177.1	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918254925	390	95.03	16	385	13	375	3.3e-111	366.2	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
2918254926	257	67.79	3	257	32	273	9.2e-38	124.9	COG2273	Beta-glucanase, GH16 family	355
2918254927	241	99.21	1	238	3	254	6.0e-90	294.9	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918254928	328	97.52	1	320	7	321	1.2e-67	223.2	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918254929	289	98.01	2	289	3	297	1.8e-69	229.2	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918254931	440	54.35	2	327	106	305	2.3e-07	26	COG0457	Tetratricopeptide (TPR) repeat	291
2918254932	133	79.84	2	118	16	114	3.0e-15	51.1	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918254933	234	98.73	1	234	3	236	4.5e-90	295.6	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918254934	245	95.75	1	245	6	253	2.4e-35	116.8	COG0730	Uncharacterized membrane protein YfcA	258
2918254935	542	97.64	16	542	2	540	0.0e+00	516.7	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918254936	169	93.38	12	169	9	135	2.7e-26	86.8	COG4520	Surface antigen	136
2918254937	353	99.06	1	340	3	317	1.1e-38	127.7	COG3980	Spore coat polysaccharide biosynthesis protein SpsG, predicted glycosyltransferase	318
2918254938	308	90.99	1	298	30	332	1.2e-77	256.3	COG2605	Predicted kinase related to galactokinase and mevalonate kinase	333
2918254939	241	60.85	9	238	3	232	4.8e-50	165.1	COG1208	NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins	358
2918254941	1292	56.79	1	205	117	325	6.8e-57	49.8	COG0457	Tetratricopeptide (TPR) repeat	291
2918254941	1292	82.88	730	1012	54	358	6.8e-57	67.4	COG0457	Tetratricopeptide (TPR) repeat	291
2918254941	1292	87.23	496	761	22	342	6.8e-57	77.3	COG0457	Tetratricopeptide (TPR) repeat	291
2918254943	677	21.15	189	252	100	154	5.8e-28	9.3	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918254943	677	23.85	123	193	104	165	5.8e-28	22.2	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918254943	677	25.77	246	321	131	197	5.8e-28	22.9	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918254943	677	28.08	302	383	116	188	5.8e-28	29.1	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918254943	677	39.23	2	126	133	234	5.8e-28	33.8	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918254944	770	95.48	1	432	18	439	0.0e+00	542.8	COG0281	Malic enzyme	432
2918254944	770	99.08	429	755	1	324	1.1e-112	370.5	COG0280	Phosphotransacetylase	327
2918254945	438	98.33	14	433	3	413	0.0e+00	508	COG1301	Na+/H+-dicarboxylate symporter	415
2918254946	612	99.01	28	604	6	603	0.0e+00	558.1	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2918254947	459	98.29	14	459	6	464	0.0e+00	573.6	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918254948	188	95.63	7	185	7	181	2.9e-63	207.3	COG3911	Predicted ATPase	183
2918254949	214	77.4	11	184	9	169	4.0e-47	154.8	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2918254950	191	96.91	1	189	6	193	3.2e-48	158.5	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
2918254951	141	91.61	2	139	11	141	3.2e-33	109.5	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2918254952	271	95.93	11	265	9	291	7.4e-23	73.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918254953	398	84.7	43	378	23	332	1.4e-33	110.9	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918254954	779	74.37	241	616	93	385	3.7e-58	192.8	COG0642	Signal transduction histidine kinase	336
2918254954	779	88.72	634	763	6	123	7.0e-14	45	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918254956	179	57.8	1	134	91	216	1.2e-16	55.5	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918254957	563	94.3	321	562	8	222	1.2e-49	162.7	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918254959	333	99.25	33	298	3	265	1.8e-107	353	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
2918254960	100	87.18	3	100	6	107	2.4e-37	122.3	COG3460	1,2-phenylacetyl-CoA epoxidase, PaaB subunit	117
2918254961	254	95.85	1	254	12	265	3.7e-80	263.6	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
2918254962	173	82.3	10	152	15	107	6.4e-28	91.5	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
2918254963	361	98.51	2	297	4	267	8.5e-68	223.3	COG1018	Ferredoxin-NADP reductase	266
2918254964	560	82.05	86	532	38	430	2.3e-38	126	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918254965	267	99.25	4	264	3	265	4.0e-81	267.1	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918254966	506	33.74	383	503	157	267	1.3e-120	60.2	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918254966	506	86.32	6	319	4	287	1.3e-120	335.3	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918254967	151	95.04	10	146	3	136	3.9e-28	92.6	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918254968	402	100	1	402	1	394	0.0e+00	473.6	COG0183	Acetyl-CoA acetyltransferase	392
2918254969	446	96.35	11	446	14	435	0.0e+00	524.7	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
2918254970	217	96.1	1	211	4	200	1.6e-48	159.5	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
2918254972	273	88.14	5	244	26	248	5.0e-40	131.8	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
2918254973	777	82.52	528	776	41	276	6.3e-27	88.5	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918254973	777	98.49	25	518	8	465	2.9e-77	254.6	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918254974	417	82.72	14	414	57	348	3.0e-45	149.4	COG3693	Endo-1,4-beta-xylanase, GH35 family	345
2918254975	311	64.87	22	305	45	225	6.4e-11	37.6	COG0500	SAM-dependent methyltransferase	257
2918254976	858	89.83	289	708	16	395	2.6e-52	173.6	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
2918254977	492	93.98	7	476	16	468	3.2e-30	99.8	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2918254978	481	83.56	255	481	35	222	9.4e-70	228.9	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2918254979	440	93.71	4	421	22	423	2.8e-32	106.7	COG3307	O-antigen ligase	424
2918254980	310	29.25	4	235	4	108	2.3e-21	72.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918254981	417	98.78	27	389	3	406	8.8e-45	148.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918254982	387	95.35	1	363	15	404	3.5e-45	150.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918254983	311	45.9	21	280	66	188	1.6e-11	38.6	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918254984	97	90.12	11	92	8	80	1.8e-12	42	COG0236	Acyl carrier protein	80
2918254985	513	95.6	2	513	14	556	2.6e-120	397.2	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918254986	675	96.17	1	637	1	527	0.0e+00	444.6	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2918254987	334	95.26	13	327	2	262	3.2e-61	201.4	COG0171	NH3-dependent NAD+ synthetase	268
2918254988	368	88.27	10	154	16	158	2.6e-05	17.4	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918254990	94	87.01	1	86	7	73	9.4e-26	84.5	COG0227	Ribosomal protein L28	77
2918254992	344	98.14	14	334	4	320	2.1e-113	373.4	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
2918254993	200	91.84	2	181	12	191	5.4e-20	64.9	COG3230	Heme oxygenase	196
2918254994	629	100	108	603	1	497	0.0e+00	776.4	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
2918254995	825	24.71	180	382	38	142	1.0e-105	28.2	COG0840	Methyl-accepting chemotaxis protein	408
2918254995	825	78.35	386	745	93	425	1.0e-105	327.3	COG0840	Methyl-accepting chemotaxis protein	408
2918254996	51	97.73	1	44	2	44	7.3e-04	13.6	COG5510	Predicted small secreted protein	44
2918254997	192	76.16	16	167	33	163	2.0e-28	93.6	COG5350	Predicted protein tyrosine phosphatase	172
2918254999	235	24.68	5	76	28	84	1.9e-20	32.4	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
2918254999	235	27.27	111	214	132	194	1.9e-20	34.2	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
2918255001	270	85.44	15	265	9	231	2.2e-67	221.6	COG4544	Uncharacterized conserved protein	260
2918255002	364	99.64	52	364	1	280	6.1e-68	224	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
2918255005	469	98.57	26	461	5	418	2.8e-130	429.6	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
2918255006	216	98.1	8	216	5	210	2.2e-83	273.8	COG0035	Uracil phosphoribosyltransferase	210
2918255007	307	89.07	66	286	18	180	4.4e-45	148.5	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918255008	165	97.56	2	165	3	162	3.1e-46	152.5	COG5472	Predicted small integral membrane protein	164
2918255009	214	98.56	2	214	2	207	1.8e-63	209	COG0135	Phosphoribosylanthranilate isomerase	208
2918255010	237	93.75	1	237	12	236	1.7e-65	215.5	COG0284	Orotidine-5'-phosphate decarboxylase	240
2918255011	318	96.06	1	317	4	320	9.2e-94	309.1	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2918255012	132	71.43	1	79	24	93	9.1e-09	29.8	COG5416	Uncharacterized integral membrane protein	98
2918255013	93	96.81	1	93	2	92	1.9e-34	112.7	COG0776	Bacterial nucleoid DNA-binding protein	94
2918255014	415	23.11	358	415	138	195	9.7e-62	28.4	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918255014	415	34.66	6	115	123	209	9.7e-62	72.7	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918255014	415	37.05	120	225	134	226	9.7e-62	62.9	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918255014	415	39.84	268	359	130	229	9.7e-62	56.3	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918255015	310	32.26	63	157	17	86	1.1e-11	9.6	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2918255015	310	39.17	148	256	131	215	1.1e-11	26.5	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2918255016	367	95.34	2	367	10	357	2.1e-118	390.4	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918255018	89	21.78	2	64	26	74	2.2e+00	5.1	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
2918255022	367	95.38	6	361	5	334	3.5e-118	389.2	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
2918255023	540	96.05	278	536	6	224	6.3e-52	170.3	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918255024	336	96.86	3	336	8	315	4.8e-108	356.1	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918255025	306	94.63	15	306	13	294	2.7e-104	343	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918255026	283	85.54	6	281	1	278	2.8e-105	346.6	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918255027	263	98.04	4	255	3	252	5.7e-91	299.2	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
2918255028	396	38.99	222	396	235	388	1.1e-19	43.4	COG2814	Predicted arabinose efflux permease, MFS family	394
2918255028	396	44.56	5	205	209	384	1.1e-19	28	COG2814	Predicted arabinose efflux permease, MFS family	394
2918255029	302	99	1	296	1	298	6.0e-45	149.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918255030	620	63.93	400	609	14	130	3.5e-19	63.5	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918255030	620	79.14	282	410	35	163	9.0e-05	16	COG0517	CBS domain	117
2918255030	620	87.94	25	283	17	242	1.2e-49	162.9	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918255032	166	97.04	2	166	2	165	9.5e-62	202.7	COG1247	L-amino acid N-acyltransferase YncA	169
2918255033	193	86.15	11	140	2	113	1.6e-18	62.3	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918255034	172	32	2	134	15	118	7.9e-07	23.1	COG0226	ABC-type phosphate transport system, periplasmic component	318
2918255035	309	97.67	6	288	1	294	7.8e-61	201.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918255036	336	95.17	1	335	16	330	5.6e-76	250.9	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918255038	508	96.44	16	493	3	462	8.1e-113	372.4	COG4529	Uncharacterized NAD(P)/FAD-binding protein YdhS	474
2918255040	229	98.02	3	203	3	200	3.0e-47	155.5	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918255041	306	95.68	15	306	9	296	2.5e-46	153.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918255043	547	99.64	1	537	1	548	0.0e+00	626.8	COG0459	Chaperonin GroEL (HSP60 family)	524
2918255044	96	98.96	1	96	1	95	7.8e-43	139.5	COG0234	Co-chaperonin GroES (HSP10)	96
2918255045	47	29.63	9	47	38	61	1.6e-03	13.4	COG5546	Uncharacterized membrane protein	80
2918255046	165	94.74	2	151	7	150	6.0e-47	153.9	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
2918255047	357	96.48	17	357	3	331	1.4e-77	255.4	COG1612	Heme A synthase	323
2918255048	220	93.58	2	210	12	215	2.4e-47	156	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918255049	59	84.48	1	59	1	49	9.5e-23	74.9	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
2918255050	822	99.18	81	787	3	727	0.0e+00	675.3	COG2217	Cation transport ATPase	713
2918255051	169	90.36	2	169	11	160	8.5e-25	82.2	COG5456	Nitrogen fixation protein FixH	166
2918255052	489	98.24	27	469	2	391	2.1e-112	370.6	COG0348	Polyferredoxin	386
2918255053	296	54.88	197	296	54	143	1.5e-46	61.1	COG2010	Cytochrome c, mono- and diheme variants	150
2918255053	296	85.98	51	205	1	141	1.5e-46	98.6	COG2010	Cytochrome c, mono- and diheme variants	150
2918255054	53	88.33	1	52	1	53	4.0e-14	47.4	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
2918255055	246	98.25	5	241	3	226	1.9e-107	352.6	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
2918255056	498	97.11	13	494	7	476	0.0e+00	769.9	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
2918255058	402	99.24	14	402	3	392	4.9e-98	323.4	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
2918255059	448	98.85	16	441	5	435	2.2e-76	252.1	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
2918255060	140	94.96	10	140	4	135	2.4e-28	93.7	COG0824	Acyl-CoA thioesterase FadM	137
2918255062	273	97	1	266	7	265	1.9e-70	232	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918255063	294	91.32	8	291	16	278	3.9e-80	263.9	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918255065	173	93.82	1	173	8	174	1.2e-54	179.7	COG4549	Uncharacterized protein YcnI	178
2918255066	538	89.76	1	114	12	125	2.3e-22	73.3	COG2372	Copper-binding protein CopC (methionine-rich)	127
2918255066	538	98.96	131	421	4	289	8.3e-38	125	COG1276	Putative copper export protein	289
2918255067	351	97.45	1	349	5	348	6.2e-114	375.8	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918255068	402	86.24	30	387	4	329	3.2e-53	175.7	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918255069	500	99.77	7	496	1	432	0.0e+00	532.4	COG0593	Chromosomal replication initiation ATPase DnaA	408
2918255070	86	96.59	1	86	1	85	4.0e-31	102.3	COG0268	Ribosomal protein S20	88
2918255071	258	99.62	1	255	2	265	7.0e-89	292.5	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918255073	280	99.64	1	280	1	273	2.6e-93	307.6	COG0266	Formamidopyrimidine-DNA glycosylase	273
2918255074	580	94.74	356	569	9	224	2.5e-49	161.5	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918255075	126	95.49	1	126	3	129	4.7e-26	86.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918255076	262	98.33	26	262	4	238	8.2e-81	265.4	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918255077	512	89.45	14	512	51	508	0.0e+00	517.9	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
2918255078	563	90.35	234	562	18	223	7.4e-54	176.8	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918255079	310	97.67	14	308	4	297	1.2e-38	127.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918255080	136	90.52	11	123	7	111	1.7e-29	96.9	COG3339	Uncharacterized membrane protein YkvA, DUF1232 family	116
2918255081	253	98.51	1	249	2	265	1.6e-53	176.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918255084	157	34.94	12	127	53	146	2.5e-14	48.2	COG4278	Uncharacterized protein	269
2918255085	346	33.88	22	256	68	149	2.8e-03	12.1	COG2202	PAS domain	232
2918255085	346	75	260	332	17	76	3.4e-05	17.6	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918255086	292	95.68	3	291	9	296	2.7e-30	100.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918255088	145	98.63	3	128	2	145	5.4e-15	50.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918255089	412	99.26	6	411	2	401	0.0e+00	563.9	COG0137	Argininosuccinate synthase	403
2918255090	75	7.02	4	57	361	392	5.2e-03	10.6	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
2918255091	79	27.08	2	65	61	99	3.2e-03	12.2	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
2918255092	986	74.87	571	978	96	390	8.7e-78	257.5	COG0642	Signal transduction histidine kinase	336
2918255096	85	15.49	1	85	473	560	8.6e-25	82	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918255097	329	99.08	5	326	2	325	8.6e-114	374.5	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918255098	176	89.47	10	176	18	170	3.6e-56	184.3	COG3807	SH3-like domain	171
2918255100	454	98.75	28	451	3	398	8.7e-43	141.3	COG0247	Fe-S oxidoreductase	388
2918255101	137	76.84	4	137	3	138	4.4e-43	142.6	COG1592	Rubrerythrin	166
2918255102	141	88.97	5	140	7	135	1.9e-29	97.1	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2918255103	457	79.71	2	356	15	289	1.9e-18	59.8	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2918255104	254	94.83	2	245	9	265	2.2e-50	166.4	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2918255105	344	92.16	1	344	23	363	2.4e-121	399.6	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
2918255106	347	59.33	47	289	25	183	6.4e-16	52.9	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918255107	183	80.09	2	178	41	209	2.8e-54	178.7	COG2173	D-alanyl-D-alanine dipeptidase	211
2918255108	225	97.74	1	221	1	216	1.6e-42	140.6	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
2918255109	163	77.25	6	155	41	186	2.8e-23	77.6	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918255110	96	91.25	15	96	6	78	1.5e-11	38.8	COG0425	TusA-related sulfurtransferase	78
2918255111	138	89.19	1	138	10	141	1.5e-62	204.9	COG4957	Predicted transcriptional regulator	148
2918255112	273	86.69	2	268	32	285	3.0e-66	218.4	COG3176	Putative hemolysin	292
2918255113	292	75.86	18	272	26	223	1.7e-33	110.7	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918255115	635	99	18	635	4	599	0.0e+00	752.8	COG0514	Superfamily II DNA helicase RecQ	590
2918255117	147	73.84	9	146	14	140	6.4e-24	79.5	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918255118	412	98.02	6	412	9	405	0.0e+00	494.2	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
2918255119	312	92.62	8	300	2	302	3.8e-45	149.1	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918255120	905	99.76	2	898	3	840	0.0e+00	1266.6	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
2918255122	173	98.7	11	164	2	153	2.8e-45	148.5	COG3449	DNA gyrase inhibitor GyrI	154
2918255123	148	97.71	1	134	3	130	3.7e-44	145.1	COG1970	Large-conductance mechanosensitive channel	130
2918255124	458	79.23	1	457	30	441	0.0e+00	480.7	COG0513	Superfamily II DNA and RNA helicase	513
2918255125	82	94.05	1	81	1	79	4.1e-38	124.4	COG3813	Uncharacterized protein	84
2918255128	258	73.68	134	255	7	104	8.9e-10	32.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918255128	258	76.8	1	124	22	117	2.8e-07	24.7	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918255130	404	100	1	395	1	390	0.0e+00	470.1	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
2918255131	456	97.76	5	454	6	442	0.0e+00	528.4	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918255132	211	98.14	1	207	3	213	5.1e-41	135.7	COG0625	Glutathione S-transferase	211
2918255135	215	60.96	2	212	61	213	5.8e-35	113.6	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918255136	627	82.54	2	627	116	753	0.0e+00	464.7	COG4993	Glucose dehydrogenase	773
2918255137	210	98.58	3	210	2	209	2.0e-42	140	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918255138	588	65.91	87	585	207	643	4.7e-98	323.6	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918255140	279	76.73	1	135	4	125	1.4e-23	24.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918255140	279	77.99	142	279	33	156	1.4e-23	59	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918255142	160	68.04	5	157	17	148	4.0e-18	59.9	COG1525	Endonuclease YncB, thermonuclease family	192
2918255143	74	47.62	1	74	45	84	1.4e-15	52.9	COG5508	Uncharacterized protein	84
2918255144	307	95.83	1	285	9	307	3.5e-77	254.5	COG0501	Zn-dependent protease with chaperone function	302
2918255145	310	93.39	2	310	17	327	7.9e-23	70.7	COG0618	nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs	332
2918255147	326	96.25	9	325	6	313	3.5e-64	211.5	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
2918255148	187	59.7	11	187	69	265	4.8e-24	80.1	COG0666	Ankyrin repeat	235
2918255151	256	92.8	20	256	7	225	1.0e-33	111.4	COG2836	Sulfite exporter TauE/SafE	232
2918255152	211	86.84	10	175	24	188	1.4e-43	143.5	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918255153	295	79.21	7	275	31	251	2.2e-14	48.8	COG0500	SAM-dependent methyltransferase	257
2918255154	88	96.63	1	88	1	86	1.2e-09	33.2	COG1987	Flagellar biosynthesis protein FliQ	89
2918255155	252	97.77	18	249	5	223	6.5e-62	203.8	COG1040	Predicted amidophosphoribosyltransferases	225
2918255156	87	97.5	2	80	2	79	2.1e-25	83.7	COG0695	Glutaredoxin	80
2918255157	278	97.12	3	276	3	272	3.4e-66	217.8	COG0388	Predicted amidohydrolase	274
2918255158	206	46.59	3	193	50	179	1.8e-09	33.1	COG0500	SAM-dependent methyltransferase	257
2918255159	189	45.07	1	83	1	64	7.4e-45	58.2	COG5319	Uncharacterized protein	142
2918255159	189	52.82	91	189	65	139	7.4e-45	88.2	COG5319	Uncharacterized protein	142
2918255160	100	95.1	1	100	4	100	3.1e-39	128	COG3162	Uncharacterized membrane protein, DUF485 family	102
2918255161	569	99.63	33	561	2	535	0.0e+00	662.1	COG4147	Na+(or H+)/acetate symporter ActP	529
2918255162	621	99.34	11	620	4	609	0.0e+00	459.3	COG2905	Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains	610
2918255164	405	97.27	9	381	9	364	4.4e-39	129.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918255165	193	52.85	4	144	117	255	1.4e-18	61.7	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2918255166	374	97.05	35	369	9	337	4.4e-109	359.3	COG4448	L-asparaginase II	339
2918255167	297	79.55	7	149	22	126	6.4e-22	72.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918255167	297	98.7	145	297	2	153	4.1e-30	99	COG3449	DNA gyrase inhibitor GyrI	154
2918255168	407	52.33	2	329	49	194	5.7e-13	44.1	COG0500	SAM-dependent methyltransferase	257
2918255169	439	97.33	40	439	3	403	0.0e+00	534.3	COG0004	Ammonia channel protein AmtB	409
2918255170	423	97.7	9	421	4	386	0.0e+00	519.4	COG0448	ADP-glucose pyrophosphorylase	393
2918255171	490	98.57	1	490	1	482	0.0e+00	529.6	COG0297	Glycogen synthase	487
2918255172	600	99.17	1	600	5	602	0.0e+00	1018.1	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
2918255173	397	28.21	2	71	130	184	9.1e-13	22.4	COG3861	Stress response protein YsnF (function unknown)	195
2918255173	397	28.21	65	146	66	120	9.1e-13	10.6	COG3861	Stress response protein YsnF (function unknown)	195
2918255173	397	64.62	237	396	53	178	9.1e-13	21	COG3861	Stress response protein YsnF (function unknown)	195
2918255174	83	67.65	1	78	16	84	5.5e-06	20.8	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918255177	42	32.43	3	40	10	33	1.1e-06	23.7	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
2918255178	362	92.74	1	355	25	356	1.7e-61	201.4	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
2918255180	295	98.34	5	295	2	297	3.6e-60	199.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918255182	557	31.08	40	216	15	129	3.3e-61	22.8	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2918255182	557	44.05	372	557	199	361	3.3e-61	177.5	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2918255183	120	90.98	1	120	8	128	1.7e-15	52	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918255184	803	5.83	1	54	268	305	0.0e+00	.3	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
2918255184	803	99.85	143	802	2	652	0.0e+00	645.4	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
2918255185	355	98.52	1	338	6	337	1.5e-126	417.2	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
2918255186	123	99.15	1	118	1	117	6.5e-54	176	COG0292	Ribosomal protein L20	118
2918255187	66	92.31	1	65	1	60	6.6e-23	75.9	COG0291	Ribosomal protein L35	65
2918255188	283	89.8	24	282	23	251	3.1e-71	234.2	COG2602	Beta-lactamase class D	254
2918255189	294	98.01	6	291	2	296	3.5e-67	221.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918255190	316	91.53	13	315	9	278	5.7e-44	145.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918255191	280	98.17	124	274	3	163	6.7e-18	58.9	COG2010	Cytochrome c, mono- and diheme variants	150
2918255192	278	73.2	2	168	34	175	4.7e-18	59.5	COG1525	Endonuclease YncB, thermonuclease family	192
2918255193	488	91.65	34	487	40	478	2.7e-128	423.2	COG4784	Putative Zn-dependent protease	479
2918255194	673	79.92	397	649	39	233	1.1e-49	163.6	COG2114	Adenylate cyclase, class 3	227
2918255195	209	98.56	1	208	2	206	1.7e-53	175.7	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918255196	382	96.72	185	373	4	180	2.5e-43	142.3	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918255200	451	91.48	15	451	42	481	0.0e+00	518.7	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
2918255201	439	88.37	46	339	5	270	1.3e-35	117.6	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918255202	299	97.01	8	299	6	297	4.6e-65	215.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918255203	397	97.22	1	388	10	393	0.0e+00	432.5	COG2814	Predicted arabinose efflux permease, MFS family	394
2918255204	274	96.45	1	274	7	278	4.1e-93	306.2	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2918255205	760	98.81	14	759	9	754	0.0e+00	1030.9	COG1882	Pyruvate-formate lyase	755
2918255206	257	94.76	16	256	5	239	6.3e-70	229.8	COG1180	Pyruvate-formate lyase-activating enzyme	260
2918255207	174	74.12	1	147	2	127	3.5e-20	67.2	COG0645	Predicted kinase	170
2918255208	360	96.42	1	359	2	351	8.8e-113	371.8	COG1377	Flagellar biosynthesis protein FlhB	363
2918255209	252	90.7	1	250	7	240	1.7e-49	163.4	COG1684	Flagellar biosynthesis protein FliR	258
2918255210	697	97.13	13	697	17	693	0.0e+00	844.6	COG1298	Flagellar biosynthesis pathway, component FlhA	696
2918255212	88	94.38	1	87	1	84	3.0e-28	92.6	COG1987	Flagellar biosynthesis protein FliQ	89
2918255213	129	73.58	30	129	29	106	1.1e-16	56	COG1677	Flagellar hook-basal body complex protein FliE	105
2918255214	139	97.83	4	138	4	138	8.6e-48	156.8	COG1558	Flagellar basal body rod protein FlgC	137
2918255215	130	94.07	2	130	7	133	1.2e-24	81.9	COG1815	Flagellar basal body rod protein FlgB	133
2918255216	452	97.29	5	447	11	440	0.0e+00	549.8	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
2918255221	144	93.24	1	144	3	140	1.4e-31	104.1	COG5443	Flagellar biosynthesis regulator FlbT	148
2918255222	126	80	5	113	24	115	1.4e-12	42.5	COG5442	Flagellar biosynthesis regulator FlaF	115
2918255223	597	65.21	326	597	136	388	2.0e-52	81.7	COG1344	Flagellin and related hook-associated protein FlgL	360
2918255223	597	79.64	2	330	2	310	2.0e-52	98.2	COG1344	Flagellin and related hook-associated protein FlgL	360
2918255224	273	74.14	1	227	59	230	9.9e-40	131.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918255226	644	58.91	381	524	4	122	5.2e-10	33.1	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918255226	644	68	527	642	6	90	1.8e-11	38.4	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918255226	644	80.2	11	358	74	389	6.9e-67	221.7	COG0642	Signal transduction histidine kinase	336
2918255227	247	92.48	6	136	6	128	2.6e-21	70.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918255229	342	95.59	4	341	11	335	3.0e-86	284.5	COG1536	Flagellar motor switch protein FliG	339
2918255231	273	87.15	5	271	32	248	3.9e-85	277.1	COG1338	Flagellar biosynthetic protein FliP	248
2918255232	104	57.45	3	96	61	141	2.1e-29	97.8	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
2918255233	222	56.38	35	197	72	208	1.5e-07	25.5	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
2918255234	577	97.99	1	575	12	548	0.0e+00	453.7	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
2918255235	169	81.76	11	169	26	155	7.2e-13	43.3	COG1580	Flagellar basal body-associated protein FliL	159
2918255236	401	98.5	75	401	4	331	2.0e-61	202.6	COG1868	Flagellar motor switch protein FliM	332
2918255238	244	58.46	90	235	75	188	6.6e-18	60	COG3334	Flagellar motility protein MotE, a chaperone for MotC folding	192
2918255239	473	86.07	8	455	17	393	1.2e-07	24	COG3144	Flagellar hook-length control protein FliK	417
2918255240	225	91.93	1	224	10	214	2.1e-45	149.8	COG1843	Flagellar hook assembly protein FlgD	222
2918255241	338	96.56	2	319	2	310	7.4e-101	332	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918255242	1127	81.73	587	987	69	390	3.1e-59	196.5	COG0642	Signal transduction histidine kinase	336
2918255242	1127	94.05	270	352	4	82	4.2e-02	12	COG2770	HAMP domain	83
2918255243	490	98.33	16	489	3	473	0.0e+00	531.9	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918255244	390	99.49	1	390	1	394	0.0e+00	432.4	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
2918255245	211	66.44	12	211	16	209	2.8e-39	129.7	COG1284	Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains	289
2918255246	399	95.57	10	387	2	346	5.2e-94	309.5	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2918255247	280	97.56	30	273	2	241	5.1e-67	220	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918255248	306	97.66	3	298	2	293	2.9e-79	260.7	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918255249	596	90.28	12	297	18	277	9.1e-109	267.5	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918255249	596	91.67	333	596	17	280	9.1e-109	94.3	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918255250	376	99.43	1	364	2	352	1.1e-121	401.2	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918255251	360	89.95	4	357	5	344	6.3e-48	158.2	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918255252	473	99.57	6	473	2	468	2.5e-117	387.4	COG0277	FAD/FMN-containing dehydrogenase	459
2918255253	157	98.68	1	151	3	151	1.2e-65	215.1	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
2918255255	287	96.68	1	285	5	295	4.3e-35	116.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918255256	558	97.13	1	558	4	578	0.0e+00	567.4	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918255257	205	60	1	203	130	330	1.2e-52	173.8	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918255258	104	21.19	20	99	56	126	3.1e-17	57.3	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918255260	132	97.48	4	121	3	118	2.7e-28	93.2	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
2918255261	402	14.38	242	396	598	703	6.8e-20	34.6	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
2918255261	402	21.71	29	198	354	513	6.8e-20	29	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
2918255262	282	95.02	1	282	10	295	5.2e-36	119.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918255263	483	96.71	4	468	8	448	1.2e-115	381.7	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918255264	643	90.4	263	635	37	375	1.0e-32	108.1	COG4585	Signal transduction histidine kinase	365
2918255265	233	99.53	15	230	1	210	5.7e-52	171.2	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918255266	329	90.96	1	322	17	318	2.7e-52	172.7	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918255267	256	88.84	14	236	2	200	5.2e-48	158.3	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2918255268	370	78.79	230	370	21	124	1.1e-15	51.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918255269	328	99.03	1	324	1	306	1.6e-69	227.1	COG1893	Ketopantoate reductase	307
2918255270	344	93.98	4	341	5	316	7.2e-55	181.1	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918255271	183	85.88	16	183	16	167	2.6e-14	47.8	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918255272	443	99.21	55	443	2	377	7.9e-107	352.1	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918255273	224	75.46	1	217	60	265	9.2e-28	92.1	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918255274	247	82.05	4	247	48	271	2.1e-80	265	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918255275	282	99.26	5	282	2	268	1.4e-79	262.2	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
2918255276	129	99.21	1	128	1	126	1.4e-51	168.9	COG3232	5-carboxymethyl-2-hydroxymuconate isomerase	127
2918255277	267	99.24	1	267	1	262	2.5e-107	352.8	COG3971	2-keto-4-pentenoate hydratase	264
2918255278	270	99.22	1	255	3	255	4.9e-112	368.1	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
2918255279	484	98.33	12	483	3	473	0.0e+00	615.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918255280	158	93.98	22	149	5	129	1.0e-21	72	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918255281	507	99.16	24	500	2	476	0.0e+00	575.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918255284	47	22.69	2	46	69	122	7.4e-10	33.8	COG3409	Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases	185
2918255287	426	98.93	4	366	1	370	3.9e-58	192.1	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918255288	151	57.14	19	150	85	200	9.4e-25	82.1	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2918255290	211	20.45	1	67	2	55	2.6e-27	37.9	COG1192	Cellulose biosynthesis protein BcsQ	259
2918255290	211	49.24	50	210	112	241	2.6e-27	52.2	COG1192	Cellulose biosynthesis protein BcsQ	259
2918255292	194	90.42	23	192	11	161	9.6e-24	78.4	COG4333	Uncharacterized protein	167
2918255304	265	58.5	66	210	10	126	1.8e-11	38.4	COG2263	Predicted RNA methylase	198
2918255311	971	14.2	794	961	297	346	2.0e-44	7	COG0270	Site-specific DNA-cytosine methylase	328
2918255311	971	58.24	47	449	7	211	2.0e-44	138.5	COG0270	Site-specific DNA-cytosine methylase	328
2918255316	31	19.85	2	30	46	71	2.0e-03	13	COG5393	Uncharacterized membrane protein YqjE	131
2918255321	64	12.89	4	55	309	354	1.3e-03	12.9	COG4388	Mu-like prophage I protein	357
2918255325	326	79.92	9	272	17	219	1.1e-30	101.8	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2918255327	108	69.61	1	101	16	86	6.5e-13	43.1	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918255328	301	97.34	1	291	5	297	5.6e-32	106	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918255329	357	40.5	40	232	59	156	2.1e-04	14.8	COG2202	PAS domain	232
2918255329	357	60	270	336	16	63	1.2e-08	28.3	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918255337	166	35.94	3	128	86	177	6.0e-03	11	COG0121	Predicted glutamine amidotransferase	252
2918255338	426	36.16	263	426	233	364	1.8e-46	51	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
2918255338	426	59.45	22	252	4	220	1.8e-46	101.1	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
2918255339	87	91.76	4	86	7	84	3.5e-38	124	COG3750	Uncharacterized conserved protein, UPF0335 family	85
2918255340	89	43.85	9	87	4	60	1.8e-09	33.7	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918255345	189	86.87	12	189	13	184	5.1e-38	125.3	COG4725	N6-adenosine-specific RNA methylase IME4	198
2918255346	393	13.2	341	386	233	272	2.3e-29	40.1	COG0863	DNA modification methylase	302
2918255346	393	69.31	1	271	18	227	2.3e-29	54.4	COG0863	DNA modification methylase	302
2918255347	213	86.87	14	201	9	180	3.5e-39	129	COG4725	N6-adenosine-specific RNA methylase IME4	198
2918255350	575	12.67	420	560	765	878	2.0e-20	22.5	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
2918255350	575	27	100	367	383	625	2.0e-20	40.6	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
2918255351	400	61.19	12	316	35	198	1.5e-23	78	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2918255356	159	17.4	7	157	29	154	7.9e-14	44.4	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2918255365	100	97.85	1	89	2	92	1.5e-25	84	COG2929	Uncharacterized conserved protein, DUF497 family	93
2918255366	108	84.21	8	102	15	94	3.0e-19	64.3	COG3514	Uncharacterized conserved protein, DUF4415 family	93
2918255367	296	54.47	1	282	151	418	6.9e-14	44.7	COG1793	ATP-dependent DNA ligase	444
2918255371	27	29.79	1	27	67	94	9.9e-07	23.5	COG3549	Plasmid maintenance system killer protein	94
2918255372	109	79.81	4	103	3	85	3.7e-29	95.4	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
2918255375	306	37.2	151	306	136	228	1.4e-50	88.9	COG4422	Bacteriophage protein gp37	250
2918255375	306	55.6	1	140	2	140	1.4e-50	71.8	COG4422	Bacteriophage protein gp37	250
2918255378	296	80.43	3	292	5	263	2.2e-31	103.9	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
2918255380	269	33.48	21	183	22	96	4.4e-03	9.2	COG4565	Response regulator of citrate/malate metabolism	224
2918255384	690	93.81	14	677	7	612	1.0e-63	210.3	COG5525	Phage terminase, large subunit GpA	611
2918255386	530	97.23	7	500	2	492	1.9e-56	186.2	COG5511	Bacteriophage capsid protein	492
2918255388	110	98.13	1	107	2	106	6.4e-29	95	COG5471	Predicted phage recombinase, RecA/RadA family	107
2918255397	145	95.65	5	142	2	133	7.5e-18	59.4	COG5437	Predicted secreted protein	138
2918255404	302	86.36	178	300	12	125	4.8e-24	79	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918255405	570	9.89	487	570	358	413	1.9e-34	17.1	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918255405	570	22.44	354	508	354	480	1.9e-34	15.5	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918255405	570	47.7	6	379	5	274	1.9e-34	76	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918255406	416	96.45	10	396	9	361	3.6e-33	109.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918255408	280	98.88	6	256	3	267	3.2e-70	231.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918255409	278	97.76	4	260	6	267	1.2e-78	259	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918255411	527	89.57	73	526	44	455	3.9e-37	116.8	COG1538	Outer membrane protein TolC	457
2918255413	229	96.46	3	226	3	220	1.5e-82	270.9	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918255414	409	99.8	35	409	2	510	2.1e-53	177.1	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918255417	480	67.05	179	444	53	288	1.4e-19	62.1	COG1566	Multidrug resistance efflux pump	352
2918255419	150	80.15	6	150	27	135	2.9e-20	67.4	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918255420	430	92.72	2	426	24	469	1.7e-88	292.3	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918255421	231	93.4	6	230	10	207	6.5e-28	92.4	COG0684	Regulator of RNase E activity RraA	210
2918255422	266	98.88	3	264	3	267	4.7e-60	198.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918255423	285	100	21	284	1	255	8.1e-54	177.4	COG1712	Predicted dinucleotide-utilizing enzyme	255
2918255424	297	62.31	62	283	81	247	3.0e-16	53.5	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918255425	325	94.19	2	321	9	316	8.7e-64	210.1	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918255426	212	61.76	1	210	117	313	1.8e-50	166.5	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918255427	69	21.83	1	65	220	281	4.3e-09	31.1	COG2801	Transposase InsO and inactivated derivatives	232
2918255429	74	17.56	1	74	338	409	1.7e-24	81.6	COG3464	Transposase	402
2918255436	280	80.99	26	268	30	259	5.0e-19	63.1	COG2801	Transposase InsO and inactivated derivatives	232
2918255438	218	45.45	80	211	80	149	1.7e-24	80.7	COG2847	Copper(I)-binding protein	151
2918255439	337	48.39	1	334	107	301	8.5e-12	34.3	COG3391	DNA-binding beta-propeller fold protein YncE	381
2918255442	382	78.08	25	371	44	328	2.0e-67	222.4	COG1858	Cytochrome c peroxidase	364
2918255443	719	96.39	2	719	24	717	0.0e+00	542.3	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
2918255444	707	98.11	3	707	16	795	4.4e-93	308.2	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918255447	690	98.49	4	690	13	795	2.7e-54	175.1	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918255448	471	98.87	14	471	4	441	0.0e+00	454.6	COG3182	Uncharacterized iron-regulated membrane protein	442
2918255451	699	75	72	688	146	613	6.1e-113	368.1	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918255452	609	12.31	258	296	157	188	1.1e-26	8.4	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918255452	609	33.08	11	104	106	191	1.1e-26	41	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918255452	609	43.08	92	216	70	181	1.1e-26	39.5	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918255453	603	82.86	39	603	87	550	7.8e-62	204.6	COG2831	Hemolysin activation/secretion protein	554
2918255455	229	98.28	5	227	2	229	8.5e-55	180.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918255456	824	73.35	458	804	103	391	2.5e-52	173.8	COG0642	Signal transduction histidine kinase	336
2918255459	270	59.4	1	227	104	302	1.9e-16	55.4	COG0582	Integrase	309
2918255461	246	94.71	3	240	8	222	3.7e-47	155.6	COG1451	Predicted metal-dependent hydrolase	223
2918255462	1007	92.81	6	932	8	936	0.0e+00	541.6	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
2918255463	433	30.86	20	139	205	329	5.0e-28	7.8	COG0732	Restriction endonuclease S subunit	391
2918255463	433	66.17	155	421	137	404	5.0e-28	83.8	COG0732	Restriction endonuclease S subunit	391
2918255464	496	98.47	4	496	6	520	0.0e+00	457.4	COG0286	Type I restriction-modification system, DNA methylase subunit	489
2918255467	301	95.96	10	300	4	264	1.1e-85	281.8	COG3741	N-formylglutamate amidohydrolase	272
2918255470	334	70.45	223	303	7	68	1.6e-07	25.5	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2918255470	334	94.74	1	195	4	165	4.7e-25	82.8	COG3652	Predicted outer membrane protein	170
2918255473	433	99.52	5	425	3	419	0.0e+00	678.4	COG0499	S-adenosylhomocysteine hydrolase	420
2918255475	155	98.73	1	155	3	157	8.4e-57	186.4	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
2918255476	570	89.41	94	564	44	423	4.6e-56	185.1	COG0840	Methyl-accepting chemotaxis protein	408
2918255477	154	18.52	23	154	96	180	3.0e-13	43.8	COG4564	Signal transduction histidine kinase	459
2918255478	679	98.22	2	677	9	724	0.0e+00	494.8	COG0480	Translation elongation factor EF-G, a GTPase	697
2918255479	320	82.22	41	290	47	268	7.6e-112	367.9	COG2326	Polyphosphate kinase 2, PPK2 family	270
2918255480	401	98.99	6	400	2	393	0.0e+00	443.1	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918255481	143	94.56	1	143	7	145	2.7e-22	74.4	COG3909	Cytochrome c556	147
2918255482	352	93.42	2	339	21	361	1.7e-109	360.8	COG1858	Cytochrome c peroxidase	364
2918255483	229	96.35	11	201	4	188	6.1e-46	150.8	COG3658	Cytochrome b	192
2918255485	175	91.4	1	168	5	174	5.6e-45	148.1	COG4186	Calcineurin-like phosphoesterase superfamily protein	186
2918255486	774	64.56	268	771	214	641	9.5e-100	329.1	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918255486	774	85.71	132	213	4	75	6.3e-05	16.5	COG2770	HAMP domain	83
2918255492	210	98.7	1	210	1	228	1.1e-52	173.8	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
2918255493	282	97.89	7	282	3	281	1.1e-61	204	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2918255495	258	97.02	26	258	4	231	3.7e-90	295.9	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
2918255496	594	99.47	5	578	3	565	0.0e+00	773.2	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918255497	133	97.44	14	129	3	116	4.0e-28	92.3	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
2918255498	106	83.46	1	106	20	130	5.1e-23	76.7	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
2918255500	339	99.4	2	333	2	335	4.7e-108	356.4	COG0136	Aspartate-semialdehyde dehydrogenase	334
2918255501	308	98.95	26	307	3	285	4.8e-90	296.4	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918255502	134	78.47	3	121	26	138	4.0e-10	34.1	COG3793	Tellurite resistance protein	144
2918255503	309	95.53	1	307	10	308	8.7e-50	164.3	COG0679	Predicted permease	311
2918255504	551	91.29	51	546	36	423	2.0e-59	192.4	COG0840	Methyl-accepting chemotaxis protein	408
2918255506	924	95.87	207	922	15	664	1.1e-118	391.7	COG1199	Rad3-related DNA helicase	654
2918255507	224	23.7	27	215	86	254	3.9e-68	225.3	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2918255508	167	44.48	13	159	24	168	3.0e-11	38.1	COG2203	GAF domain	175
2918255509	902	65.76	411	881	217	652	4.3e-117	386.3	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918255509	902	95.76	9	275	6	276	1.3e-20	66.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918255510	107	97.17	1	105	2	104	1.8e-35	116.5	COG2076	Multidrug transporter EmrE and related cation transporters	106
2918255511	522	99.62	11	520	2	520	0.0e+00	540.7	COG1384	Lysyl-tRNA synthetase, class I	521
2918255514	389	79.12	30	381	24	311	1.9e-23	78	COG5330	Uncharacterized conserved protein, DUF2336 family	364
2918255516	322	99.05	4	318	1	312	5.2e-119	391.8	COG0039	Malate/lactate dehydrogenase	313
2918255517	398	99.74	1	397	1	382	0.0e+00	530.4	COG0045	Succinyl-CoA synthetase, beta subunit	387
2918255518	291	98.98	1	291	1	291	0.0e+00	431.5	COG0074	Succinyl-CoA synthetase, alpha subunit	293
2918255519	968	99.46	2	967	5	922	0.0e+00	1311.1	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
2918255520	417	99.77	1	416	1	433	0.0e+00	529.2	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2918255522	144	48.76	2	126	121	238	5.2e-16	53.5	COG2202	PAS domain	232
2918255523	416	98.5	1	416	6	400	1.6e-129	427	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918255527	497	86.93	1	399	56	434	2.3e-104	343.8	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
2918255529	504	78.61	35	486	7	436	0.0e+00	446.2	COG0595	mRNA degradation ribonuclease J1/J2	555
2918255531	253	90.1	2	252	28	291	5.2e-21	69.7	COG0842	ABC-type multidrug transport system, permease component	286
2918255532	308	99.35	1	306	2	305	1.1e-87	289	COG1131	ABC-type multidrug transport system, ATPase component	293
2918255533	282	17.51	5	59	95	132	8.5e-69	19.5	COG4711	Uncharacterized membrane protein	217
2918255533	282	100	51	282	1	217	8.5e-69	211.5	COG4711	Uncharacterized membrane protein	217
2918255537	345	49.1	111	340	42	178	5.2e-10	33.6	COG0500	SAM-dependent methyltransferase	257
2918255538	707	93.84	2	688	18	763	1.5e-49	156.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918255539	420	42.04	232	418	33	193	1.3e-25	27.7	COG0477	MFS family permease	338
2918255539	420	82.25	15	296	5	319	1.3e-25	58.2	COG0477	MFS family permease	338
2918255540	328	78.79	211	328	22	125	6.7e-30	97.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918255541	967	62.69	252	553	140	386	9.7e-109	208.5	COG0642	Signal transduction histidine kinase	336
2918255541	967	75.38	592	967	92	388	9.7e-109	155.8	COG0642	Signal transduction histidine kinase	336
2918255542	128	85.71	9	127	6	119	1.4e-23	77.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918255543	173	94.01	5	168	6	162	2.6e-32	106.7	COG3685	Ferritin-like metal-binding protein YciE	167
2918255544	123	93.23	2	122	6	129	4.7e-22	72.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918255545	545	90.61	14	417	33	389	1.2e-51	171.4	COG0642	Signal transduction histidine kinase	336
2918255546	497	90.04	247	494	7	241	1.1e-66	74.3	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
2918255546	497	96.55	6	253	2	253	1.1e-66	143.8	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
2918255547	495	99.12	20	494	2	453	2.7e-126	416.5	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918255548	419	72.22	1	345	1	325	2.4e-23	77.4	COG0439	Biotin carboxylase	449
2918255549	400	47.26	215	400	17	197	4.7e-13	5.4	COG0477	MFS family permease	338
2918255549	400	78.59	5	275	8	308	4.7e-13	38.1	COG0477	MFS family permease	338
2918255550	347	99.34	2	305	2	301	4.9e-98	322.4	COG0031	Cysteine synthase	300
2918255551	345	96.97	6	338	7	326	2.9e-51	169.2	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2918255552	343	93.71	13	305	19	301	1.2e-77	255.4	COG0031	Cysteine synthase	300
2918255553	287	99.26	5	286	1	269	9.9e-80	262.5	COG0253	Diaminopimelate epimerase	272
2918255555	338	29.74	6	84	12	80	5.7e-50	60.6	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918255555	338	90.95	96	322	13	223	5.7e-50	105.5	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918255556	291	79.85	22	290	55	272	1.0e-88	292.1	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918255557	245	97.01	2	243	7	266	1.4e-60	199.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918255558	420	97.27	18	396	9	364	2.2e-37	123.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918255560	388	96.95	11	387	2	351	2.6e-128	422.3	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2918255561	505	89.04	85	402	3	270	1.7e-38	127.1	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918255562	840	38.34	539	840	399	656	1.5e-74	182.3	COG4192	Signal transduction histidine kinase regulating phosphoglycerate transport system	673
2918255562	840	58.69	25	430	7	401	1.5e-74	60	COG4192	Signal transduction histidine kinase regulating phosphoglycerate transport system	673
2918255563	445	98.72	1	445	6	466	0.0e+00	557.2	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918255564	451	88.37	45	348	3	268	5.1e-55	181.8	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918255565	570	97.24	12	566	11	539	1.2e-118	391.4	COG1178	ABC-type Fe3+ transport system, permease component	540
2918255566	378	92.35	20	377	6	331	8.2e-126	414.5	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918255567	227	97.3	7	226	3	218	9.5e-54	177.3	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918255568	183	85.65	1	179	3	181	2.5e-28	91	COG0406	Broad specificity phosphatase PhoE	208
2918255569	269	88.44	1	269	15	297	2.8e-37	114.7	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918255570	214	31.64	37	160	30	85	3.4e-05	16.8	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2918255571	338	98.67	39	335	2	298	4.5e-75	247.4	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918255572	250	72.73	49	216	32	183	3.3e-04	15.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918255573	914	82.49	31	758	66	390	2.1e-52	170.2	COG0642	Signal transduction histidine kinase	336
2918255573	914	91.73	768	893	6	127	1.3e-15	49.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918255574	366	95.75	5	365	5	342	7.1e-122	401.6	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918255575	729	98.71	148	716	2	538	0.0e+00	501.3	COG1178	ABC-type Fe3+ transport system, permease component	540
2918255576	356	98.67	56	353	2	298	3.1e-76	251.1	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918255577	249	97.84	13	243	3	229	1.7e-70	231.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918255578	152	60.32	1	132	55	168	7.4e-14	46	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918255579	199	88.95	36	194	13	165	6.5e-15	50.1	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918255580	253	99.21	1	252	1	252	8.0e-70	229.9	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2918255581	602	97.49	23	463	7	395	4.3e-107	353.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918255582	313	98.43	2	313	2	314	8.6e-106	348.8	COG2025	Electron transfer flavoprotein, alpha subunit	313
2918255583	181	72.8	1	181	69	258	3.4e-63	208	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2918255584	149	38.84	2	149	1	141	1.7e-44	147.4	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2918255585	149	41.1	72	140	4	70	1.8e-35	53.4	COG0517	CBS domain	117
2918255585	149	93.25	2	126	12	163	1.8e-35	71.8	COG0517	CBS domain	117
2918255586	342	97.41	1	323	1	301	4.7e-74	243.9	COG1893	Ketopantoate reductase	307
2918255587	244	94.98	1	244	9	254	1.0e-33	111.5	COG0730	Uncharacterized membrane protein YfcA	258
2918255588	434	50.91	221	427	3	197	2.5e-19	24.6	COG0477	MFS family permease	338
2918255588	434	66.84	13	248	16	271	2.5e-19	41.9	COG0477	MFS family permease	338
2918255589	146	81.48	4	140	21	152	2.4e-06	23	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918255591	152	92.02	1	126	13	162	6.0e-26	86.2	COG0517	CBS domain	117
2918255592	309	89.63	1	309	5	315	1.8e-98	324.4	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2918255593	582	56.54	51	581	15	459	4.6e-100	330.2	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
2918255594	256	84.88	2	205	16	161	1.8e-15	51.4	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918255595	490	99.16	1	470	4	477	0.0e+00	557.9	COG0469	Pyruvate kinase	477
2918255596	229	90.52	1	226	12	221	2.8e-48	159	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918255597	212	89.57	2	205	8	196	5.8e-38	124.7	COG0352	Thiamine monophosphate synthase	211
2918255598	431	50.65	217	429	3	196	1.0e-19	22.4	COG0477	MFS family permease	338
2918255598	431	61.88	10	249	30	266	1.0e-19	45.2	COG0477	MFS family permease	338
2918255599	563	90.59	75	558	39	423	9.1e-57	187.6	COG0840	Methyl-accepting chemotaxis protein	408
2918255600	299	98.01	2	296	2	296	5.7e-65	214.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918255601	206	95.35	6	206	2	206	1.9e-39	130.5	COG0625	Glutathione S-transferase	211
2918255602	305	32.76	183	255	54	110	2.1e-26	13.6	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2918255602	305	88.51	10	190	1	154	2.1e-26	72.3	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2918255603	293	80.51	15	289	45	267	1.8e-62	204.7	COG2503	Predicted secreted acid phosphatase	274
2918255605	224	90.52	3	223	14	223	2.1e-51	169.1	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918255606	473	99.36	24	473	2	467	9.8e-125	411.5	COG0277	FAD/FMN-containing dehydrogenase	459
2918255607	352	96.39	19	352	9	328	2.1e-79	261.8	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918255608	627	82.49	16	170	8	153	5.7e-32	105.4	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918255608	627	98.68	243	624	3	376	4.2e-95	313.7	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918255609	126	22.05	4	98	15	57	1.8e-04	15.7	COG3224	Antibiotic biosynthesis monooxygenase (ABM) superfamily enzyme	195
2918255610	286	97.25	1	286	7	289	1.7e-82	271.6	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
2918255611	231	98.31	1	231	3	235	5.3e-88	288.8	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918255612	248	96.09	1	248	8	253	3.9e-119	391.5	COG4674	ABC-type uncharacterized transport system, ATPase component	249
2918255613	384	96.9	13	362	5	317	2.4e-86	284.4	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918255614	541	98.34	241	539	4	299	7.7e-101	331.5	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918255615	435	97.81	19	394	3	360	6.3e-71	233.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918255616	507	39.92	105	277	33	127	8.3e-05	15.9	COG3409	Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases	185
2918255617	301	95.15	2	297	15	308	3.8e-76	250.6	COG3386	Sugar lactone lactonase YvrE	307
2918255618	378	97.38	3	378	4	374	1.6e-116	383.9	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
2918255619	1024	48.71	872	996	2	114	4.4e-37	76.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918255619	1024	49.57	710	832	2	116	4.4e-37	45	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918255619	1024	68.53	278	694	120	389	9.4e-72	237.5	COG0642	Signal transduction histidine kinase	336
2918255620	617	84.01	115	464	60	390	9.2e-48	157.3	COG0642	Signal transduction histidine kinase	336
2918255620	617	93.98	481	610	6	130	1.1e-09	31.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918255622	515	95.67	3	515	10	562	8.0e-73	240.9	COG0747	ABC-type transport system, periplasmic component	556
2918255623	285	57.58	38	279	5	156	1.9e-38	127.3	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918255624	340	97.73	70	335	4	261	2.6e-56	186	COG1192	Cellulose biosynthesis protein BcsQ	259
2918255625	320	63.45	1	281	1	243	5.6e-15	50.2	COG5534	Plasmid replication initiator protein	383
2918255627	1609	98.05	3	1609	29	1590	0.0e+00	1987.1	COG2902	NAD-specific glutamate dehydrogenase	1592
2918255628	300	98.01	3	299	1	295	1.2e-56	187.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918255630	189	96.45	13	181	3	165	1.6e-49	162.7	COG1247	L-amino acid N-acyltransferase YncA	169
2918255631	416	45.17	218	415	19	191	1.1e-20	26.6	COG0477	MFS family permease	338
2918255631	416	68.93	9	272	7	270	1.1e-20	42.2	COG0477	MFS family permease	338
2918255632	294	97.34	4	294	1	293	2.1e-62	206.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918255633	794	67.01	123	656	128	391	1.1e-57	189.8	COG0642	Signal transduction histidine kinase	336
2918255633	794	88.72	667	794	9	126	3.5e-15	49.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918255636	195	87.79	10	192	14	164	2.7e-17	57.5	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
2918255637	267	79.62	38	264	45	255	4.0e-16	53.4	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2918255638	390	95.06	2	390	16	400	0.0e+00	486.1	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2918255639	309	98.39	1	306	5	310	2.0e-116	383.3	COG0078	Ornithine carbamoyltransferase	310
2918255640	313	98.26	9	308	4	285	1.8e-88	291.2	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
2918255642	236	99.58	2	236	2	237	1.0e-81	268.2	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918255643	253	98.82	2	248	3	253	3.3e-87	286.6	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918255644	333	96.59	3	333	7	318	9.8e-79	259.5	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918255646	246	98.2	2	231	3	220	6.9e-82	268.8	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
2918255647	308	96.68	6	308	5	295	3.4e-72	238.2	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918255648	388	95.63	8	374	8	357	3.2e-53	175.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918255650	357	92.76	27	336	4	336	1.4e-41	138.1	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918255652	399	92.33	2	397	15	387	6.7e-58	191.4	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918255653	136	86.86	1	122	10	128	1.7e-05	18.6	COG4319	Ketosteroid isomerase homolog	137
2918255655	550	88.49	3	252	3	248	7.1e-55	180.2	COG0388	Predicted amidohydrolase	274
2918255655	550	95.99	262	538	3	265	1.7e-53	176.1	COG0171	NH3-dependent NAD+ synthetase	268
2918255657	189	83.15	1	171	4	151	2.3e-06	21.8	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
2918255659	311	98.01	11	307	2	296	2.5e-65	215.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918255660	408	94.68	12	408	13	386	6.6e-32	105.1	COG2814	Predicted arabinose efflux permease, MFS family	394
2918255663	297	98.67	2	297	1	297	2.6e-75	248.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918255664	473	49.09	251	462	8	195	1.5e-36	9.3	COG0477	MFS family permease	338
2918255664	473	69.97	1	268	8	275	1.5e-36	115.2	COG0477	MFS family permease	338
2918255665	250	99.57	14	245	1	229	9.0e-73	239.4	COG1794	Aspartate/glutamate racemase	230
2918255666	449	80.41	1	440	1	427	1.9e-97	321.9	COG3898	Uncharacterized membrane-anchored protein	531
2918255667	633	98.1	155	617	7	420	1.5e-21	71.9	COG4223	Uncharacterized conserved protein	422
2918255668	252	88.8	9	246	3	224	3.8e-26	86.4	COG1587	Uroporphyrinogen-III synthase	248
2918255669	309	95.77	3	308	3	296	4.9e-111	365.3	COG0181	Porphobilinogen deaminase	307
2918255670	300	56.63	6	281	54	211	9.9e-16	53.1	COG0500	SAM-dependent methyltransferase	257
2918255671	357	98.55	1	345	1	339	5.0e-130	428	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
2918255672	489	85.77	1	488	29	474	0.0e+00	507	COG0513	Superfamily II DNA and RNA helicase	513
2918255673	191	97.27	8	189	6	183	2.4e-43	142.8	COG2032	Cu/Zn superoxide dismutase	179
2918255674	141	94.48	1	141	5	141	1.0e-42	140.2	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2918255685	72	19.53	2	72	75	140	2.4e-03	11.6	COG4093	Uncharacterized protein	338
2918255686	124	97.39	1	115	2	113	2.5e-41	135.1	COG3502	Uncharacterized conserved protein, DUF952 family	115
2918255687	357	99.03	43	357	2	308	1.2e-105	347.6	COG0167	Dihydroorotate dehydrogenase	310
2918255688	409	92.61	168	408	6	243	7.8e-46	150.3	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918255689	650	98.65	37	645	2	587	0.0e+00	863.9	COG0441	Threonyl-tRNA synthetase	589
2918255690	365	79.32	25	278	12	199	6.3e-19	62.4	COG0412	Dienelactone hydrolase	236
2918255691	335	15.27	277	333	35	74	7.3e-05	9.7	COG3103	Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family	205
2918255691	335	27.48	105	256	92	163	7.3e-05	5	COG3103	Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family	205
2918255693	106	64.71	8	95	16	81	6.3e-15	49.4	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918255694	448	92.54	5	352	23	332	3.4e-82	270.9	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918255698	251	12.54	3	80	15	52	6.2e-17	11.3	COG0863	DNA modification methylase	302
2918255698	251	22.11	121	220	203	269	6.2e-17	43.3	COG0863	DNA modification methylase	302
2918255700	103	28.85	6	52	5	34	2.8e-06	5.8	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
2918255700	103	29.81	66	101	53	83	2.8e-06	14.2	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
2918255702	391	73.73	82	377	80	326	5.8e-21	69.7	COG0582	Integrase	309
2918255704	172	87.63	5	172	18	180	2.6e-37	123	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918255705	342	97.83	7	342	4	319	5.3e-85	279.8	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918255706	815	95.33	92	815	36	750	4.5e-38	125.1	COG4774	Outer membrane receptor for monomeric catechols	750
2918255707	383	89.16	1	381	2	396	7.1e-69	227.3	COG3182	Uncharacterized iron-regulated membrane protein	442
2918255708	65	9.25	1	46	419	461	8.9e-03	9.4	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918255709	857	85.5	5	836	3	757	0.0e+00	737.8	COG0525	Valyl-tRNA synthetase	877
2918255710	286	12	14	104	66	92	3.7e-28	5.7	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
2918255710	286	51.11	163	286	102	216	3.7e-28	90	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
2918255711	226	92.24	11	222	13	214	1.4e-54	180	COG2345	Predicted transcriptional regulator, ArsR family	218
2918255712	205	97.07	2	204	2	200	6.1e-68	223.4	COG0605	Superoxide dismutase	204
2918255713	389	98.73	1	388	1	388	3.2e-81	268.3	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918255714	207	98.1	1	207	1	206	1.4e-72	238.4	COG2808	Predicted FMN-binding regulatory protein PaiB	209
2918255715	652	61.8	186	637	208	592	5.5e-13	41.2	COG3211	Secreted phosphatase, PhoX family	616
2918255716	318	19.25	257	318	206	256	5.2e-58	8.2	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
2918255716	318	70.19	46	256	20	205	5.2e-58	181.3	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
2918255717	289	98.95	13	286	1	282	4.1e-83	273.5	COG2301	Citrate lyase beta subunit	283
2918255718	286	99.63	1	284	1	272	2.3e-79	261.2	COG3777	Hydroxyacyl-ACP dehydratase HTD2, hotdog domain	273
2918255719	486	99.36	20	484	3	468	3.0e-124	410	COG0277	FAD/FMN-containing dehydrogenase	459
2918255720	480	98.54	4	480	2	473	0.0e+00	499.1	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918255721	326	98.06	1	326	1	303	5.3e-71	233.9	COG1893	Ketopantoate reductase	307
2918255722	650	98.88	50	623	4	445	0.0e+00	668.2	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
2918255723	209	96.15	1	182	3	177	3.9e-67	219.9	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
2918255724	361	99.17	1	356	1	360	0.0e+00	510.2	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
2918255725	875	99.24	2	863	7	922	0.0e+00	877.6	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
2918255726	562	97.49	160	562	7	395	2.9e-117	387	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918255727	320	98.34	1	301	1	296	2.1e-55	183.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918255728	250	99.25	3	249	2	267	1.1e-68	226.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918255729	401	98.25	1	400	8	401	6.4e-64	210.8	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918255730	351	81.05	11	338	6	330	3.6e-87	287.3	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918255731	310	97.97	1	309	4	341	2.0e-72	238.9	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2918255732	265	88.98	2	229	9	226	4.7e-65	213.8	COG0704	Phosphate uptake regulator	240
2918255734	712	86.7	3	427	43	394	8.2e-10	29.1	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2918255734	712	90.57	405	652	18	238	4.2e-53	175.1	COG2114	Adenylate cyclase, class 3	227
2918255735	575	95.36	18	575	26	559	2.5e-91	301.8	COG2831	Hemolysin activation/secretion protein	554
2918255736	283	97.84	1	283	5	321	7.8e-86	283	COG0627	S-formylglutathione hydrolase FrmB	316
2918255737	372	99.45	2	370	3	366	0.0e+00	561	COG1062	Zn-dependent alcohol dehydrogenase	366
2918255738	300	96.68	6	299	9	299	2.3e-71	235.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918255740	186	94.74	5	184	5	184	3.1e-25	83.3	COG3009	Uncharacterized lipoprotein YmbA	190
2918255741	556	95.48	1	555	14	541	8.0e-121	398.8	COG3008	Paraquat-inducible protein B	553
2918255742	417	94.74	1	412	16	411	6.8e-99	326.2	COG2995	Uncharacterized paraquat-inducible protein A	418
2918255743	272	96.65	27	261	6	236	9.7e-50	163.7	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918255744	284	96.11	11	280	7	278	8.1e-52	170.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918255745	215	93.42	1	215	14	226	5.5e-71	233.5	COG0765	ABC-type amino acid transport system, permease component	222
2918255746	234	92.54	1	215	15	225	8.4e-66	216.5	COG0765	ABC-type amino acid transport system, permease component	222
2918255747	267	99.17	13	262	2	241	9.4e-107	350.2	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918255750	422	31.25	14	140	190	304	2.8e-20	21.2	COG0457	Tetratricopeptide (TPR) repeat	291
2918255750	422	39.95	255	413	70	216	2.8e-20	23	COG0457	Tetratricopeptide (TPR) repeat	291
2918255750	422	55.98	106	282	60	265	2.8e-20	33	COG0457	Tetratricopeptide (TPR) repeat	291
2918255753	353	66.03	3	266	117	359	3.7e-10	35.1	COG0457	Tetratricopeptide (TPR) repeat	291
2918255754	364	97.85	6	345	5	323	3.0e-65	214.9	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2918255755	254	99.63	8	253	1	267	4.6e-52	171.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918255756	210	33.24	1	153	22	146	1.2e-20	68.7	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918255757	332	11.44	7	74	5	47	1.2e-10	5	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918255757	332	57.18	69	322	132	346	1.2e-10	29.5	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918255758	186	91.44	4	171	17	187	1.5e-09	32.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918255759	382	63.55	40	154	20	87	7.5e-08	26.5	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2918255761	201	47.09	34	159	11	91	1.0e-15	52.4	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918255765	429	95.64	1	425	10	426	3.3e-127	419.3	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
2918255766	502	64.87	21	250	35	215	4.5e-10	32.2	COG0500	SAM-dependent methyltransferase	257
2918255767	345	88.58	24	339	23	309	1.4e-17	58.5	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2918255771	496	96.15	54	487	14	388	6.2e-38	125.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918255772	763	98.31	36	736	12	710	0.0e+00	853.4	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918255774	1447	26.43	93	331	306	453	1.1e-27	38.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918255774	1447	30.36	377	661	284	453	1.1e-27	40	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918255774	1447	37.32	214	380	236	444	1.1e-27	36.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918255774	1447	42.5	655	958	309	546	1.1e-27	19.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918255775	327	81.79	8	304	7	262	1.1e-55	183.6	COG1216	Glycosyltransferase, GT2 family	305
2918255776	809	18.04	588	805	347	447	3.0e-41	47.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918255776	809	36.43	451	658	243	446	3.0e-41	77.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918255776	809	52.86	17	595	174	469	3.0e-41	41.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918255778	523	14.32	1	76	9	77	8.7e-31	22.5	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2918255778	523	78.22	94	490	90	466	8.7e-31	83.4	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2918255779	421	98.13	8	419	5	372	2.5e-108	357.2	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2918255780	353	55.57	12	352	258	591	4.8e-125	413	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
2918255781	411	75.31	1	404	89	396	5.3e-32	106.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918255782	194	47.09	36	167	16	96	1.0e-12	42.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918255784	478	96.9	350	476	4	128	4.8e-42	136.9	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2918255784	478	100	8	341	1	335	1.8e-126	416.3	COG0836	Mannose-1-phosphate guanylyltransferase	333
2918255785	217	61.15	7	178	45	203	1.4e-39	131	COG1484	DNA replication protein DnaC	254
2918255788	705	97.61	1	701	18	711	0.0e+00	716.5	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918255789	446	96.15	23	436	13	387	1.9e-26	87.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918255790	389	96.66	1	389	9	384	6.5e-62	204.1	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918255791	373	91.52	12	373	12	367	2.6e-41	135.9	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918255792	34	7.89	1	34	1	33	5.1e-12	39.9	COG1004	UDP-glucose 6-dehydrogenase	414
2918255793	136	26.79	1	116	306	417	1.0e-32	108	COG1004	UDP-glucose 6-dehydrogenase	414
2918255794	317	98.44	1	316	3	318	2.6e-77	255.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918255795	287	98.63	1	287	1	287	1.8e-123	405.9	COG1209	dTDP-glucose pyrophosphorylase	286
2918255796	302	98.94	1	291	2	280	5.4e-104	341.9	COG1091	dTDP-4-dehydrorhamnose reductase	281
2918255797	358	98	2	350	3	345	0.0e+00	532.3	COG1088	dTDP-D-glucose 4,6-dehydratase	340
2918255798	183	95.48	1	178	7	175	2.8e-67	220.3	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
2918255799	340	97.87	13	338	2	323	0.0e+00	431.9	COG1087	UDP-glucose 4-epimerase	329
2918255801	1098	21.73	942	1093	159	226	6.8e-33	70.7	COG1216	Glycosyltransferase, GT2 family	305
2918255801	1098	35.46	830	956	4	114	6.8e-33	35.9	COG1216	Glycosyltransferase, GT2 family	305
2918255801	1098	56.94	360	409	7	47	1.0e-07	16.8	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
2918255801	1098	72.22	298	358	8	59	1.0e-07	12.3	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
2918255802	460	96.81	18	262	2	244	4.1e-88	289.6	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
2918255803	282	96.6	17	282	10	265	7.9e-65	213.2	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2918255805	356	77.26	3	356	88	403	3.7e-20	67.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918255806	324	82.75	2	323	3	261	8.5e-46	150.9	COG1216	Glycosyltransferase, GT2 family	305
2918255808	524	36.96	2	291	191	326	2.9e-03	12.1	COG0457	Tetratricopeptide (TPR) repeat	291
2918255809	642	37.5	4	142	195	332	9.8e-28	41	COG0457	Tetratricopeptide (TPR) repeat	291
2918255809	642	66.3	123	348	93	336	9.8e-28	53.4	COG0457	Tetratricopeptide (TPR) repeat	291
2918255810	595	25.38	3	80	113	178	7.8e-20	32.5	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918255810	595	48.46	63	209	109	234	7.8e-20	33.1	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918255811	333	98.55	8	330	3	341	1.0e-110	364.3	COG1089	GDP-D-mannose dehydratase	345
2918255812	354	99.13	1	347	2	342	0.0e+00	585.8	COG1089	GDP-D-mannose dehydratase	345
2918255813	241	41.58	4	231	44	159	1.1e-09	33.6	COG0500	SAM-dependent methyltransferase	257
2918255814	136	21.15	1	132	121	179	7.9e-06	21.3	COG0500	SAM-dependent methyltransferase	257
2918255815	229	55.91	5	224	54	209	6.9e-15	50.5	COG0500	SAM-dependent methyltransferase	257
2918255817	326	97.82	1	326	2	315	6.7e-57	188.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918255818	533	10.56	371	532	495	554	2.0e-14	20	COG2303	Choline dehydrogenase or related flavoprotein	542
2918255818	533	49.12	5	309	12	290	2.0e-14	28.7	COG2303	Choline dehydrogenase or related flavoprotein	542
2918255819	394	90.88	43	380	13	321	2.0e-20	67.9	COG0859	ADP-heptose:LPS heptosyltransferase	334
2918255820	324	87.96	15	318	21	305	2.6e-19	64.1	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2918255821	501	53.53	3	377	112	308	8.5e-04	14.4	COG0457	Tetratricopeptide (TPR) repeat	291
2918255823	341	93.87	2	317	4	340	1.8e-35	118.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918255824	399	98.53	1	391	4	406	2.6e-57	189.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918255825	256	46.95	16	254	43	173	3.3e-10	35.2	COG0500	SAM-dependent methyltransferase	257
2918255826	303	48.77	60	273	51	169	4.1e-20	66.6	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2918255827	369	8.45	235	349	258	286	6.3e-16	2.9	COG3594	Fucose 4-O-acetylase or related acetyltransferase	343
2918255827	369	17.49	5	190	3	62	6.3e-16	51.9	COG3594	Fucose 4-O-acetylase or related acetyltransferase	343
2918255829	834	60.64	70	386	153	400	9.7e-17	54.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918255830	1940	32.68	1456	1649	282	464	2.7e-20	16.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918255830	1940	34.82	879	1124	268	462	2.7e-20	20.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918255830	1940	34.82	1101	1336	266	460	2.7e-20	4.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918255830	1940	35.89	1602	1881	286	486	2.7e-20	17.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918255830	1940	37.5	391	599	253	462	2.7e-20	21.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918255830	1940	47.32	1202	1477	196	460	2.7e-20	8.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918255830	1940	55.18	576	914	176	484	2.7e-20	18.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918255832	238	90.09	18	237	15	223	2.0e-54	178.9	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918255833	409	94.79	13	408	19	400	1.0e-115	381.1	COG3135	Predicted benzoate:H+ symporter BenE	402
2918255834	134	84.87	2	133	14	142	1.7e-24	80.9	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
2918255837	170	94.32	1	170	7	172	2.2e-62	204.9	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
2918255838	304	93.28	6	300	18	267	7.6e-51	167.6	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918255839	116	94.35	1	116	8	124	4.5e-42	137.7	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
2918255840	589	98.65	1	589	1	584	0.0e+00	1160.5	COG3960	Glyoxylate carboligase	592
2918255841	306	98.01	3	298	3	297	2.8e-68	225.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918255843	285	96.75	37	279	2	239	2.7e-74	243.7	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918255845	541	93	286	535	6	244	9.6e-61	199.1	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918255848	387	99.19	4	380	3	369	1.9e-104	344	COG1932	Phosphoserine aminotransferase	365
2918255849	172	41.62	12	172	24	182	1.8e-34	113.6	COG3448	CBS-domain-containing membrane protein	382
2918255850	384	84.14	7	361	3	331	3.3e-68	224.7	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
2918255851	430	99.77	1	429	1	429	0.0e+00	611.6	COG0104	Adenylosuccinate synthase	430
2918255854	330	95.13	29	314	10	302	1.3e-44	146.9	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918255855	332	99.02	15	321	3	305	4.1e-91	300.1	COG1131	ABC-type multidrug transport system, ATPase component	293
2918255856	59	75.81	1	51	15	61	3.9e-15	50.2	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
2918255857	685	64.86	184	683	214	643	1.0e-116	385	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918255858	755	77.49	310	721	61	325	1.2e-52	172.7	COG0668	Small-conductance mechanosensitive channel	316
2918255859	229	91.38	1	226	9	220	1.8e-47	156.3	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918255860	589	96.76	25	582	3	539	0.0e+00	449.1	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918255861	424	98.25	1	415	7	400	6.5e-123	405.2	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918255862	399	99.22	1	397	1	380	0.0e+00	527.7	COG0045	Succinyl-CoA synthetase, beta subunit	387
2918255863	291	98.98	1	291	1	291	5.2e-130	427.6	COG0074	Succinyl-CoA synthetase, alpha subunit	293
2918255864	294	99.59	45	290	1	245	3.8e-73	240	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918255865	336	100	7	331	1	331	1.9e-102	337.7	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918255869	181	77.51	1	180	13	174	1.5e-18	63	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918255870	507	50.13	246	494	19	210	9.2e-34	19.7	COG0477	MFS family permease	338
2918255870	507	83.29	4	295	4	322	9.2e-34	94.9	COG0477	MFS family permease	338
2918255871	261	99.25	2	260	2	267	1.1e-70	232.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918255872	384	97.29	97	377	4	290	1.8e-46	153.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918255873	345	98.46	4	334	2	320	0.0e+00	443.8	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
2918255874	327	89.66	1	327	23	343	8.3e-116	381.3	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
2918255875	357	72.11	2	250	2	257	7.5e-31	101.9	COG3199	Predicted polyphosphate- or ATP-dependent NAD kinase	355
2918255876	656	99.02	1	651	6	611	0.0e+00	643.2	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
2918255881	210	21.89	120	186	122	172	9.1e-24	19.3	COG2849	Antitoxin component YwqK of the YwqJK toxin-antitoxin module	230
2918255881	210	51.93	18	161	110	230	9.1e-24	64.7	COG2849	Antitoxin component YwqK of the YwqJK toxin-antitoxin module	230
2918255882	671	9.17	567	670	507	559	0.0e+00	.4	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2918255882	671	98.96	1	555	5	576	0.0e+00	544.1	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2918255883	876	98.14	10	867	3	792	0.0e+00	896.5	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918255885	366	6.87	318	359	299	321	6.6e-77	8.5	COG3520	Predicted component of the type VI protein secretion system	335
2918255885	366	89.55	1	325	16	315	6.6e-77	247.3	COG3520	Predicted component of the type VI protein secretion system	335
2918255886	606	99.52	6	606	4	621	0.0e+00	574.1	COG3519	Type VI protein secretion system component VasA	621
2918255887	171	84.08	4	150	13	144	6.8e-21	69	COG3518	Predicted component of the type VI protein secretion system	157
2918255888	166	92.41	1	162	1	146	1.2e-35	117.4	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2918255889	495	98.79	1	495	5	493	0.0e+00	707	COG3517	Predicted component of the type VI protein secretion system	495
2918255890	185	95.86	2	170	2	163	4.9e-62	203	COG3516	Predicted component of the type VI protein secretion system	169
2918255891	394	92.63	16	373	8	334	9.7e-40	127.2	COG3515	Predicted component of the type VI protein secretion system	346
2918255893	291	60.98	70	281	89	249	1.2e-22	75.1	COG3455	Type VI protein secretion system component VasF	262
2918255894	454	87.67	6	411	7	397	6.1e-53	174.5	COG3522	Predicted component of the type VI protein secretion system	446
2918255896	181	28.57	123	179	93	130	1.6e-04	6	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918255896	181	33.08	19	73	21	64	1.6e-04	8.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918255897	301	97.86	1	279	6	279	2.3e-92	304.2	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2918255898	624	98.97	15	611	4	482	3.5e-43	140.2	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2918255899	89	89.89	1	87	2	81	5.5e-19	63.4	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
2918255900	117	94.95	1	113	1	94	6.4e-15	49.7	COG3668	Plasmid stabilization system protein ParE	98
2918255901	115	85.29	2	115	19	134	1.9e-17	58.1	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918255902	253	93.99	1	253	9	274	7.3e-57	187.5	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918255903	115	90.44	1	115	11	133	1.3e-29	97.6	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918255904	372	98.2	2	372	3	383	1.2e-74	246.6	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918255905	480	9.3	6	89	148	187	5.2e-21	34.9	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918255905	480	78.6	57	455	66	403	5.2e-21	39.9	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918255906	98	7.67	8	95	4	78	2.5e-06	20.2	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2918255907	387	97.68	16	386	4	382	2.4e-58	192.8	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918255908	307	98.34	2	298	2	297	2.4e-49	163.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918255909	348	99	47	348	1	298	1.3e-36	121.2	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918255910	349	98.87	1	345	4	352	9.0e-125	411.2	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918255911	316	90.62	28	314	13	273	6.3e-74	243.4	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918255912	266	91.39	1	258	14	257	3.8e-78	257	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918255913	167	57.14	19	146	20	95	1.8e-12	41.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918255928	620	84.44	28	419	42	383	1.1e-48	160	COG4695	Phage portal protein BeeE	398
2918255930	568	98.37	5	567	8	550	0.0e+00	506.7	COG4626	Phage terminase-like protein, large subunit, contains N-terminal HTH domain	546
2918255932	125	27.74	16	122	73	115	7.3e-04	12.7	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2918255938	303	68.96	4	301	92	322	2.3e-25	84.4	COG0582	Integrase	309
2918255942	232	20.08	1	67	3	55	9.6e-20	26.7	COG1192	Cellulose biosynthesis protein BcsQ	259
2918255942	232	51.89	62	215	119	255	9.6e-20	37.9	COG1192	Cellulose biosynthesis protein BcsQ	259
2918255946	129	69.41	1	117	46	163	3.0e-16	54.2	COG4396	Mu-like prophage host-nuclease inhibitor protein Gam	170
2918255959	254	53.85	141	238	2	71	9.1e-10	33.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918255962	740	71.59	90	352	7	195	2.2e-36	119.5	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918255964	293	81.19	15	293	57	328	1.8e-32	107.8	COG0582	Integrase	309
2918255965	333	88.34	1	292	37	324	1.2e-78	259	COG4644	Transposase and inactivated derivatives, TnpA family	323
2918255969	387	16.39	44	77	26	35	1.4e-03	4.1	COG2888	Predicted RNA-binding protein involved in translation, contains  Zn-ribbon domain, DUF1610 family	61
2918255969	387	26.23	117	146	20	35	1.4e-03	6.6	COG2888	Predicted RNA-binding protein involved in translation, contains  Zn-ribbon domain, DUF1610 family	61
2918255969	387	98.67	162	387	1	223	6.6e-70	229.5	COG2135	Putative SOS response-associated peptidase YedK	226
2918255971	293	88.69	2	282	27	277	2.1e-50	166.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918255979	253	96.05	1	165	5	150	1.6e-38	124.6	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
2918255981	426	98.71	26	408	4	386	4.7e-83	274.2	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918255982	347	25.52	177	236	93	129	1.2e-03	7.9	COG1730	Prefoldin subunit 5	145
2918255982	347	35.17	273	333	88	138	1.2e-03	3.8	COG1730	Prefoldin subunit 5	145
2918255983	528	64.38	7	133	27	120	3.6e-10	33.4	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2918255984	773	98.24	105	773	15	795	5.0e-39	129.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918255985	359	95.05	17	358	12	318	7.3e-75	241.8	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918255986	171	89.25	1	171	15	180	1.4e-37	123.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918255987	408	98.91	8	384	2	363	4.3e-42	139	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918255988	494	11.84	389	493	347	413	3.2e-36	32.1	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918255988	494	48.23	12	322	9	281	3.2e-36	79	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918255989	425	98.5	13	410	7	401	1.2e-128	424.1	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918255990	275	12.88	5	60	25	75	8.5e-49	22.2	COG0372	Citrate synthase	390
2918255990	275	51.26	48	268	176	378	8.5e-49	143.7	COG0372	Citrate synthase	390
2918255991	492	99.37	4	484	2	477	0.0e+00	590.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918255992	256	24.39	171	233	186	245	6.9e-45	38.7	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918255992	256	58.54	17	169	2	145	6.9e-45	109.5	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918255993	368	67.25	165	354	23	176	1.0e-11	39	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
2918255993	368	96.18	3	154	4	154	2.1e-08	28.3	COG1225	Peroxiredoxin	157
2918255994	269	47.31	12	262	7	243	3.1e-92	304.2	COG1129	ABC-type sugar transport system, ATPase component	500
2918255995	452	96.95	27	451	11	392	0.0e+00	458.2	COG4214	ABC-type xylose transport system, permease component	394
2918255996	364	97.95	18	354	7	340	2.3e-117	386.6	COG4213	ABC-type xylose transport system, periplasmic component	341
2918255997	440	99.54	2	440	3	438	0.0e+00	690.9	COG2115	Xylose isomerase	438
2918255998	489	98.01	1	489	5	496	0.0e+00	482.6	COG1070	Sugar (pentulose or hexulose) kinase	502
2918255999	343	96.33	4	343	3	317	9.6e-48	157.3	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918256000	353	97.44	7	351	7	311	1.2e-72	239.4	COG2017	Galactose mutarotase or related enzyme	308
2918256001	325	94.36	1	316	10	310	9.1e-85	279	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918256002	360	92.48	13	329	16	310	3.8e-76	250.5	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918256003	522	98.8	6	511	5	499	0.0e+00	597.4	COG1129	ABC-type sugar transport system, ATPase component	500
2918256004	326	97.25	1	325	6	323	2.7e-81	267.6	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918256005	526	98.33	5	501	3	473	2.1e-66	218.8	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918256006	308	96.32	4	303	4	291	7.1e-49	160.7	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918256007	292	95.15	1	288	12	305	1.1e-74	245.9	COG3386	Sugar lactone lactonase YvrE	307
2918256008	343	98.67	16	318	2	298	1.2e-54	180.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918256009	357	96.48	1	357	11	339	0.0e+00	434.3	COG4213	ABC-type xylose transport system, periplasmic component	341
2918256010	528	98.6	1	506	6	499	0.0e+00	615.2	COG1129	ABC-type sugar transport system, ATPase component	500
2918256011	398	95.94	5	398	16	393	0.0e+00	500.9	COG4214	ABC-type xylose transport system, permease component	394
2918256012	312	89.17	4	303	6	318	6.7e-41	135	COG0673	Predicted dehydrogenase	342
2918256013	608	97.58	12	592	11	574	0.0e+00	598	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918256014	112	81.82	15	106	5	85	5.9e-07	23.5	COG1359	Quinol monooxygenase YgiN	100
2918256015	290	85.48	4	166	20	178	5.7e-34	111.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918256017	448	96.92	26	439	11	388	2.0e-38	126.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918256018	732	77.78	149	729	145	697	3.2e-130	429.4	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918256019	555	75.25	3	555	156	690	4.2e-116	383	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918256020	712	82.23	216	574	69	392	1.9e-58	193.4	COG0642	Signal transduction histidine kinase	336
2918256020	712	90.98	588	712	7	127	1.9e-15	51.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918256022	835	92.43	2	438	13	415	3.0e-66	216.8	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
2918256023	299	95.02	16	299	10	295	5.8e-45	148.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918256025	311	99.34	2	298	2	300	4.0e-82	270.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918256026	200	98.12	1	200	3	211	7.7e-50	164.1	COG0655	Multimeric flavodoxin WrbA	207
2918256027	319	99.69	1	314	1	321	0.0e+00	490.6	COG0435	Glutathionyl-hydroquinone reductase	324
2918256034	248	99.63	1	247	1	267	2.7e-64	211.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918256038	870	88.42	296	698	27	400	5.1e-49	162.2	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
2918256039	147	96.03	1	126	2	122	1.9e-46	151.4	COG0853	Aspartate 1-decarboxylase	126
2918256040	462	66.75	25	453	128	390	2.4e-55	182.9	COG0642	Signal transduction histidine kinase	336
2918256041	339	78.59	2	324	50	328	1.7e-68	225.2	COG1740	Ni,Fe-hydrogenase I small subunit	355
2918256042	495	21.77	14	154	2	124	4.7e-94	125.3	COG0374	Ni,Fe-hydrogenase I large subunit	545
2918256042	495	63.36	138	495	193	550	4.7e-94	181.1	COG0374	Ni,Fe-hydrogenase I large subunit	545
2918256043	73	18.72	5	69	56	96	1.2e-03	12.3	COG3897	Predicted nicotinamide N-methyase	218
2918256045	1370	32.63	733	883	88	149	1.1e-20	15.7	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918256045	1370	46.32	964	1092	67	154	1.1e-20	15.7	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918256045	1370	47.37	1258	1369	94	183	1.1e-20	35.9	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918256045	1370	63.89	3	464	234	647	1.5e-106	351.5	COG1020	Non-ribosomal peptide synthetase component F	642
2918256046	544	94.59	362	543	2	176	2.1e-68	222.8	COG1838	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain	184
2918256046	544	99.33	41	347	2	298	2.6e-89	293.3	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
2918256047	226	73.29	1	211	78	291	8.0e-55	180.6	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2918256048	494	82.23	121	494	66	389	5.8e-60	198.4	COG0642	Signal transduction histidine kinase	336
2918256049	541	69.18	73	432	125	418	3.4e-43	141.3	COG0840	Methyl-accepting chemotaxis protein	408
2918256050	305	95.02	14	304	10	295	1.6e-34	113.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918256051	300	98.34	9	300	3	298	2.0e-70	232.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918256052	552	98.92	1	550	1	549	0.0e+00	579.2	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918256053	503	96.87	12	491	14	477	0.0e+00	461.5	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918256054	149	96.45	1	141	3	138	3.7e-30	99.4	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
2918256055	319	94.68	1	285	7	291	3.7e-75	247.3	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918256056	495	97.57	1	490	6	486	0.0e+00	720.8	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
2918256057	789	98.46	4	784	12	780	0.0e+00	1358.4	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
2918256058	283	91.36	3	280	6	280	1.6e-63	208.8	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2918256060	289	98.01	5	289	2	296	1.8e-60	199.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918256061	250	99.23	1	247	1	257	3.4e-11	37.2	COG0730	Uncharacterized membrane protein YfcA	258
2918256063	255	11.64	17	203	365	500	5.6e-07	21.5	COG1196	Chromosome segregation ATPase	1163
2918256064	141	96.99	9	141	4	132	1.1e-31	104.1	COG3766	Uncharacterized membrane protein YjfL, UPF0719 family	133
2918256066	682	90.82	67	676	38	423	3.6e-58	188.5	COG0840	Methyl-accepting chemotaxis protein	408
2918256067	270	98.88	24	268	3	267	4.1e-63	207.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918256068	62	20.12	1	59	257	321	1.8e-13	44.7	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918256069	191	44.16	1	169	218	391	5.7e-41	135.8	COG0642	Signal transduction histidine kinase	336
2918256070	560	84.47	133	554	65	423	7.9e-64	209.8	COG0840	Methyl-accepting chemotaxis protein	408
2918256071	586	99.43	56	585	3	522	0.0e+00	608.4	COG4986	ABC-type anion transport system, duplicated permease component	523
2918256072	435	95.54	273	432	4	153	5.4e-42	137.4	COG4754	Uncharacterized protein	157
2918256072	435	97.21	7	263	4	247	3.6e-90	295.9	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918256073	467	20.33	284	369	232	293	4.9e-91	27.3	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2918256073	467	27.87	365	461	208	292	4.9e-91	22.8	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2918256073	467	92.46	2	297	10	291	4.9e-91	249.4	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2918256076	581	55.18	18	508	56	588	3.5e-115	380	COG0474	Magnesium-transporting ATPase (P-type)	917
2918256077	330	50.84	13	322	16	316	2.9e-10	29.3	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918256081	215	34.01	1	70	130	196	8.5e-35	30.8	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918256081	215	61.93	73	215	73	194	8.5e-35	84.9	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918256082	280	55.35	1	101	4	91	1.4e-16	5.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918256082	280	88.05	121	280	17	156	1.4e-16	51.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918256084	392	90.8	255	378	12	159	7.8e-15	49.3	COG0517	CBS domain	117
2918256084	392	99.15	33	258	1	234	2.9e-37	122.7	COG1994	Zn-dependent protease (includes SpoIVFB)	230
2918256085	800	99.24	3	793	3	783	0.0e+00	800.9	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
2918256086	54	7.12	10	53	235	260	5.0e-04	13.7	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918256087	279	77.99	1	147	5	128	4.0e-20	26.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918256087	279	79.87	151	279	30	156	4.0e-20	45.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918256088	307	91.03	13	301	25	308	1.7e-38	126.7	COG0501	Zn-dependent protease with chaperone function	302
2918256089	559	98.89	99	558	5	451	0.0e+00	434.2	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
2918256090	253	99.63	1	252	1	267	7.8e-66	216.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918256092	410	99.8	18	410	2	510	1.4e-77	256.3	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918256093	253	97.35	10	235	2	221	5.5e-79	258.8	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918256094	474	92.31	18	465	12	371	1.0e-48	149.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918256095	239	96.25	1	238	8	238	4.6e-64	210.3	COG5343	Anti-sigma-K factor RskA	240
2918256096	188	93.01	12	188	6	178	5.6e-39	128	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918256098	299	74.34	1	167	1	168	2.8e-48	158.3	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2918256100	617	64.4	129	332	52	288	1.2e-32	63.8	COG0457	Tetratricopeptide (TPR) repeat	291
2918256100	617	66.58	6	212	112	356	1.2e-32	53.6	COG0457	Tetratricopeptide (TPR) repeat	291
2918256101	452	20.54	20	109	205	272	1.2e-95	59.4	COG0790	TPR repeat	292
2918256101	452	45.92	266	412	99	250	1.2e-95	113.1	COG0790	TPR repeat	292
2918256101	452	58.61	107	283	80	273	1.2e-95	168.2	COG0790	TPR repeat	292
2918256102	466	95.38	35	456	16	387	1.1e-28	93.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918256103	691	95.78	1	688	31	711	0.0e+00	699.3	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918256104	668	87.02	22	653	78	620	0.0e+00	445.7	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918256105	571	85.58	18	561	88	621	1.7e-106	349.3	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918256106	196	93.79	7	183	11	176	8.9e-63	205.4	COG0279	Phosphoheptose isomerase	176
2918256109	302	97.82	11	301	3	316	1.9e-58	192.5	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918256110	369	40.57	31	326	16	172	1.7e-08	27.3	COG0641	Sulfatase maturation enzyme AslB, radical SAM superfamily	378
2918256111	360	82.47	125	360	2	241	3.5e-29	95.9	COG1209	dTDP-glucose pyrophosphorylase	286
2918256111	360	90.8	3	119	14	161	8.7e-12	38.9	COG0517	CBS domain	117
2918256112	334	97.82	6	323	4	317	6.8e-80	263	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918256113	344	99.14	3	344	3	346	1.6e-99	327.4	COG2089	Sialic acid synthase SpsE, contains C-terminal SAF domain	347
2918256115	94	76.92	1	93	1	90	7.1e-15	49.7	COG2963	Transposase and inactivated derivatives	116
2918256116	285	86.97	17	282	30	276	5.0e-45	148.3	COG2801	Transposase InsO and inactivated derivatives	232
2918256117	301	98.01	5	301	1	295	3.3e-64	211.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918256118	187	95.83	1	187	2	185	7.6e-72	235.1	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
2918256119	530	99.23	1	520	1	517	0.0e+00	926.6	COG3634	Alkyl hydroperoxide reductase subunit AhpF	520
2918256120	76	23.24	1	73	211	276	2.7e-13	44.4	COG2801	Transposase InsO and inactivated derivatives	232
2918256121	151	85.83	22	140	14	116	9.2e-28	90.4	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2918256124	2256	21.61	2130	2248	428	548	2.4e-87	47.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918256124	2256	25.54	329	466	322	464	2.4e-87	56.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918256124	2256	28.04	3	185	313	469	2.4e-87	56.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918256124	2256	28.57	177	349	295	454	2.4e-87	59.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918256124	2256	32.32	381	579	289	469	2.4e-87	47.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918256124	2256	33.21	699	906	260	445	2.4e-87	68.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918256124	2256	55	460	712	145	452	2.4e-87	49.7	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918256125	980	27.91	4	120	40	130	3.3e-104	7.1	COG4644	Transposase and inactivated derivatives, TnpA family	323
2918256125	980	99.39	614	940	2	325	3.3e-104	333.6	COG4644	Transposase and inactivated derivatives, TnpA family	323
2918256127	54	41.88	1	54	5	53	7.7e-10	33.7	COG2963	Transposase and inactivated derivatives	116
2918256128	2033	22.02	1630	1669	27	50	3.3e-10	7.6	COG2926	Uncharacterized conserved protein YeeX, DUF496 family	109
2918256128	2033	23.85	1670	1727	30	55	3.3e-10	3.6	COG2926	Uncharacterized conserved protein YeeX, DUF496 family	109
2918256128	2033	36.7	1563	1624	29	68	3.3e-10	6.3	COG2926	Uncharacterized conserved protein YeeX, DUF496 family	109
2918256130	1476	7.56	1020	1081	230	259	1.5e-11	5.4	COG1015	Phosphopentomutase	397
2918256130	1476	7.56	1152	1200	229	258	1.5e-11	3.7	COG1015	Phosphopentomutase	397
2918256130	1476	7.81	945	998	226	256	1.5e-11	1.8	COG1015	Phosphopentomutase	397
2918256130	1476	7.81	1101	1159	228	258	1.5e-11	4.6	COG1015	Phosphopentomutase	397
2918256130	1476	7.81	1277	1323	229	259	1.5e-11	4.4	COG1015	Phosphopentomutase	397
2918256130	1476	7.81	1318	1381	229	259	1.5e-11	1.2	COG1015	Phosphopentomutase	397
2918256130	1476	8.31	907	957	227	259	1.5e-11	5.3	COG1015	Phosphopentomutase	397
2918256131	556	66.55	57	448	38	226	1.5e-21	71.5	COG2801	Transposase InsO and inactivated derivatives	232
2918256134	260	78.49	3	254	15	233	4.8e-17	57	COG0500	SAM-dependent methyltransferase	257
2918256135	368	98.13	1	368	5	372	4.3e-124	408.7	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2918256136	144	81.4	8	134	20	124	5.0e-05	16.4	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2918256137	416	60.64	29	400	149	396	5.2e-27	89.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918256138	290	54.12	4	282	55	205	1.8e-07	25.8	COG0500	SAM-dependent methyltransferase	257
2918256140	325	99.37	1	319	1	316	1.3e-27	90.9	COG3980	Spore coat polysaccharide biosynthesis protein SpsG, predicted glycosyltransferase	318
2918256141	237	85.48	1	220	2	207	3.2e-64	210.4	COG1861	Spore coat polysaccharide biosynthesis protein SpsF, cytidylyltransferase family	241
2918256143	308	95.02	1	294	13	317	1.9e-67	222.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918256144	612	87.82	9	608	73	620	1.2e-125	412.9	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918256145	994	24.69	51	311	282	382	6.1e-34	7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918256145	994	98.29	612	993	5	406	6.1e-34	102.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918256146	837	52.33	542	832	42	187	9.3e-15	47.4	COG0500	SAM-dependent methyltransferase	257
2918256146	837	76.63	7	384	65	346	1.9e-21	70.9	COG0457	Tetratricopeptide (TPR) repeat	291
2918256150	226	20.83	1	72	1	55	8.9e-24	47.7	COG1192	Cellulose biosynthesis protein BcsQ	259
2918256150	226	56.44	53	216	111	259	8.9e-24	30.4	COG1192	Cellulose biosynthesis protein BcsQ	259
2918256152	450	55.43	5	444	67	270	3.1e-16	54.7	COG0457	Tetratricopeptide (TPR) repeat	291
2918256155	356	100	2	355	1	353	8.4e-95	311.6	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918256157	569	93.86	298	568	12	225	5.2e-44	144	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918256158	31	23.93	1	31	5	32	6.5e-05	17.8	COG2963	Transposase and inactivated derivatives	116
2918256159	351	84.01	4	351	56	386	4.0e-54	178.9	COG0642	Signal transduction histidine kinase	336
2918256160	245	97.41	17	245	3	228	2.8e-70	230.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918256161	384	94.1	2	374	19	385	1.5e-54	179.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918256162	1047	99.61	1	1024	3	1012	0.0e+00	1160.1	COG0841	Multidrug efflux pump subunit AcrB	1009
2918256163	485	98.48	9	471	2	454	2.4e-121	399.9	COG1538	Outer membrane protein TolC	457
2918256164	441	48.83	235	433	8	194	2.9e-13	26.1	COG0477	MFS family permease	338
2918256164	441	57.7	30	259	5	225	2.9e-13	21.6	COG0477	MFS family permease	338
2918256166	689	11.07	582	671	415	468	6.5e-56	7.1	COG3119	Arylsulfatase A or related enzyme	475
2918256166	689	28.69	361	531	260	399	6.5e-56	95.4	COG3119	Arylsulfatase A or related enzyme	475
2918256166	689	43.24	8	290	4	214	6.5e-56	86.6	COG3119	Arylsulfatase A or related enzyme	475
2918256168	205	61.27	18	188	6	179	5.5e-28	92.3	COG4584	Transposase	278
2918256169	80	30	1	80	178	255	1.2e-18	62.2	COG1484	DNA replication protein DnaC	254
2918256170	185	41.55	1	155	112	229	1.3e-11	38.8	COG2801	Transposase InsO and inactivated derivatives	232
2918256171	291	96.68	6	291	1	291	1.4e-42	140.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918256173	590	85.71	15	590	79	558	2.9e-64	212.1	COG2831	Hemolysin activation/secretion protein	554
2918256174	596	69.84	4	309	103	359	1.5e-25	83.9	COG0457	Tetratricopeptide (TPR) repeat	291
2918256175	670	22.12	100	286	40	177	1.8e-112	21.3	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918256175	670	56.57	300	667	261	613	1.8e-112	347.3	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918256176	84	58.12	1	82	23	90	3.0e-11	38.1	COG2963	Transposase and inactivated derivatives	116
2918256177	142	100	1	142	1	144	7.9e-45	146.6	COG5458	Uncharacterized protein	144
2918256178	318	95.68	1	306	5	292	8.0e-42	137.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918256179	204	95.57	1	202	9	202	9.9e-60	196	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
2918256180	237	99.14	1	234	1	230	7.2e-80	261.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918256183	561	90.82	52	556	38	423	7.8e-67	220.4	COG0840	Methyl-accepting chemotaxis protein	408
2918256186	147	90.78	6	146	8	135	4.6e-32	104.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918256187	292	89.26	10	282	3	243	6.3e-53	174	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
2918256188	406	89	34	406	44	407	1.2e-47	155.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918256189	225	87.12	1	223	25	281	4.4e-23	72.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918256192	75	14.72	2	72	74	117	3.1e-07	24.4	COG4973	Site-specific recombinase XerC	299
2918256198	284	73.48	34	267	8	201	1.4e-42	138.9	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918256199	338	95.45	71	329	4	255	8.4e-55	180.4	COG1192	Cellulose biosynthesis protein BcsQ	259
2918256205	312	79.2	1	189	1	179	9.7e-48	156.8	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2918256206	121	82.91	1	110	1	97	4.3e-14	47.1	COG2963	Transposase and inactivated derivatives	116
2918256208	417	58.19	4	412	143	380	1.1e-06	23.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918256211	313	84.36	23	312	25	326	9.9e-21	62.4	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2918256213	208	90.24	1	208	11	232	3.0e-32	106.4	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
2918256215	451	75.95	8	201	26	205	1.0e-74	88.4	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
2918256215	451	90.72	234	450	5	219	1.0e-74	154.6	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
2918256216	669	97.36	1	669	22	795	1.2e-43	142.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918256217	178	96.26	1	177	6	185	1.3e-31	104.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918256218	248	65.23	3	247	54	235	4.1e-12	41	COG0500	SAM-dependent methyltransferase	257
2918256219	186	97.86	6	182	3	185	1.2e-31	104.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918256220	150	93.38	5	150	6	146	2.4e-36	119.1	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
2918256221	239	64.39	85	239	40	124	1.0e-21	71.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918256222	701	94.07	2	696	47	808	0.0e+00	456.5	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918256224	167	77.5	23	167	28	151	6.0e-16	53.3	COG5419	Uncharacterized protein	160
2918256226	80	46.15	4	78	5	64	8.0e-13	43.7	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918256228	94	29.41	1	86	6	60	1.3e-05	19.4	COG3620	Predicted transcriptional regulator with C-terminal CBS domains	187
2918256231	127	93.23	2	127	5	128	4.3e-24	79.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918256232	134	88.51	1	134	12	142	6.1e-57	186.1	COG4957	Predicted transcriptional regulator	148
2918256233	644	79.75	18	446	50	242	9.9e-18	57.7	COG2202	PAS domain	232
2918256233	644	97.27	439	629	4	181	2.4e-54	176.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918256235	70	40.77	1	68	15	67	8.1e-06	21.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918256236	164	55.38	43	153	2	73	5.1e-16	53.8	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918256237	78	53.08	6	77	2	70	6.0e-18	60.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918256238	57	16.8	2	51	32	73	2.1e-03	11.9	COG3063	Tfp pilus assembly protein PilF	250
2918256239	98	93.46	1	98	3	102	1.8e-33	108.9	COG5489	Uncharacterized conserved protein, DUF736 family	107
2918256250	46	22.69	2	45	69	122	2.2e-10	35.1	COG3409	Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases	185
2918256252	592	84.82	17	592	86	560	7.2e-53	174.4	COG2831	Hemolysin activation/secretion protein	554
2918256253	590	69.02	3	329	106	359	6.8e-25	82.3	COG0457	Tetratricopeptide (TPR) repeat	291
2918256254	706	23.08	26	188	24	167	5.5e-110	6.8	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918256254	706	75.32	185	699	145	614	5.5e-110	354.1	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918256255	418	72.93	65	384	56	346	1.2e-20	65.6	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
2918256256	88	54.62	1	85	3	73	7.1e-08	27.9	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918256257	291	86.67	2	283	23	282	5.6e-28	92	COG4974	Site-specific recombinase XerD	300
2918256260	301	18.6	31	102	40	87	4.2e-09	6.4	COG2253	Predicted nucleotidyltransferase component of viral defense system	258
2918256260	301	27.13	171	282	151	220	4.2e-09	22.9	COG2253	Predicted nucleotidyltransferase component of viral defense system	258
2918256262	102	65.81	1	96	1	77	7.8e-14	46.4	COG2963	Transposase and inactivated derivatives	116
2918256264	222	80.45	8	216	27	203	2.0e-30	99.7	COG0036	Pentose-5-phosphate-3-epimerase	220
2918256265	267	86.67	6	259	4	237	8.7e-40	130.9	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
2918256266	380	48.96	2	300	23	163	8.4e-05	15.9	COG0191	Fructose/tagatose bisphosphate aldolase	286
2918256267	78	34.03	2	77	99	163	3.9e-03	11.1	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
2918256270	178	82.3	2	176	22	207	7.6e-39	127.8	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2918256280	342	75.92	4	315	3	229	4.8e-43	141.8	COG4823	Abortive infection bacteriophage resistance protein	299
2918256281	148	35.61	8	115	30	76	1.7e-04	15.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918256284	190	88.94	1	187	3	203	9.6e-55	179.9	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2918256289	115	98.13	1	108	2	106	1.1e-23	77.7	COG5471	Predicted phage recombinase, RecA/RadA family	107
2918256293	372	73.47	1	372	128	498	4.3e-79	260.6	COG5511	Bacteriophage capsid protein	492
2918256301	1083	9.11	625	697	408	458	4.6e-63	30.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918256301	1083	15.89	690	789	369	457	4.6e-63	26	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918256301	1083	19.82	1	167	398	508	4.6e-63	6.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918256301	1083	29.82	454	634	299	465	4.6e-63	65.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918256301	1083	51.25	784	1071	204	490	4.6e-63	86.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918256301	1083	66.96	52	516	70	444	4.6e-63	31.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918256306	61	42.03	1	55	26	54	4.3e-04	14.5	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2918256310	379	98.57	6	355	4	347	3.2e-123	405	COG5397	Uncharacterized protein	349
2918256312	126	83.45	1	125	3	118	1.9e-15	51.1	COG3415	Transposase	138
2918256313	176	94.78	44	173	2	128	2.1e-22	73.1	COG3335	Transposase	132
2918256324	90	31.54	1	88	8	89	3.9e-05	17.9	COG1484	DNA replication protein DnaC	254
2918256325	473	69.01	1	260	85	280	2.8e-24	80	COG4584	Transposase	278
2918256326	457	97.55	14	179	4	162	2.5e-47	155	COG3436	Transposase	157
2918256327	163	51.61	11	156	23	134	3.3e-08	27.8	COG3318	Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C motif	216
2918256332	400	90.49	23	294	25	281	2.6e-26	86.7	COG4584	Transposase	278
2918256333	483	86.27	13	483	14	503	2.7e-102	337.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918256334	462	99.36	1	462	4	470	0.0e+00	718.2	COG1282	NAD/NADP transhydrogenase beta subunit	463
2918256335	449	94.15	3	408	8	377	2.2e-59	195.2	COG5659	SRSO17 transposase	385
2918256336	401	94.44	4	391	8	381	2.4e-114	376.3	COG3328	Transposase (or an inactivated derivative)	379
2918256337	306	68.18	3	297	18	287	1.5e-91	301.3	COG3328	Transposase (or an inactivated derivative)	379
2918256338	94	18.18	1	86	313	384	1.6e-16	54.5	COG3328	Transposase (or an inactivated derivative)	379
2918256342	343	82.58	4	343	19	345	9.1e-113	371.2	COG3328	Transposase (or an inactivated derivative)	379
2918256343	171	33.58	70	165	47	91	1.4e-06	22.5	COG3335	Transposase	132
2918256344	170	91.37	22	169	10	136	4.9e-17	56.2	COG3415	Transposase	138
2918256347	149	63.25	19	143	4	77	4.9e-19	63	COG2963	Transposase and inactivated derivatives	116
2918256348	117	61.35	4	114	39	138	9.0e-25	81.4	COG3436	Transposase	157
2918256350	67	22.92	1	67	229	297	3.7e-19	63.7	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918256351	293	84.21	12	292	11	282	1.2e-78	258.8	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
