gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
649976104	568	42.27	230	546	87	400	1.0e-80	294	COG0593	Chromosomal replication initiation ATPase DnaA	408
649976106	436	59.86	1	436	3	438	0.0e+00	661	COG2115	Xylose isomerase	438
649976109	269	21.19	9	230	6	237	4.0e-16	78.6	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
649976110	719	21.24	34	449	15	378	4.0e-30	127	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649976111	655	23.09	119	614	27	491	3.0e-37	150	COG0366	Glycosidase	505
649976115	355	32.26	214	273	1	61	3.0e-08	52.9	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
649976116	150	37.01	17	136	5	130	2.0e-22	98.8	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
649976117	274	48.86	8	271	3	264	6.0e-75	273	COG0345	Pyrroline-5-carboxylate reductase	266
649976118	1314	35.72	19	962	2	845	0.0e+00	655	COG1643	HrpA-like RNA helicase	845
649976120	208	28.14	1	196	1	191	2.0e-19	89.1	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
649976121	2167	56.73	1	965	1	934	0.0e+00	1336	COG0178	Excinuclease UvrABC ATPase subunit	935
649976122	566	51.6	10	564	9	571	0.0e+00	692	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
649976123	324	36.62	5	316	1	307	2.0e-53	203	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
649976124	478	19.2	14	403	11	382	6.0e-21	95.8	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
649976125	434	35.87	16	291	15	273	6.0e-46	178	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
649976126	246	60.34	3	236	2	238	7.0e-80	290	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
649976128	138	41.03	12	125	1	116	3.0e-15	74.5	COG0594	RNase P protein component	117
649976129	79	52.31	15	79	9	73	7.0e-22	95.4	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
649976130	462	33.02	72	451	4	429	1.0e-84	307	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
649976131	172	21.01	14	151	14	136	7.0e-08	50.6	COG1943	REP element-mobilizing transposase RayT	136
649976132	162	33.33	1	142	1	127	1.0e-20	92.7	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
649976134	427	39.34	1	427	1	413	2.0e-92	332	COG0373	Glutamyl-tRNA reductase	414
649976135	296	35.68	41	278	60	288	2.0e-46	179	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
649976136	217	32.84	4	203	2	202	2.0e-33	136	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
649976137	423	35.08	48	421	14	393	6.0e-82	297	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
649976138	280	24.81	26	277	5	247	2.0e-24	106	COG0388	Predicted amidohydrolase	274
649976139	506	32.73	19	496	21	488	2.0e-109	390	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
649976140	194	27.36	1	190	1	197	2.0e-11	63	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
649976141	367	27.97	8	365	18	417	2.0e-61	230	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
649976142	680	32.73	25	675	17	649	0.0e+00	462	COG2766	Predicted Ser/Thr protein kinase	649
649976143	391	51.23	22	388	4	356	7.0e-120	424	COG0337	3-dehydroquinate synthetase	360
649976146	131	30.71	3	128	1	120	5.0e-13	66.7	COG3293	Transposase	124
649976153	182	31.5	30	150	4	130	1.0e-19	89.7	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
649976155	442	45.58	3	418	2	405	1.0e-119	423	COG1252	NADH dehydrogenase, FAD-containing subunit	405
649976156	572	29.77	11	559	20	532	1.0e-80	294	COG0659	Sulfate permease or related transporter, MFS superfamily	554
649976161	273	39.11	7	273	1	262	6.0e-62	230	COG0005	Purine nucleoside phosphorylase	262
649976162	229	38.43	1	212	1	203	3.0e-41	161	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
649976164	333	33.8	117	329	5	210	2.0e-42	166	COG1515	Deoxyinosine 3'endonuclease (endonuclease V)	212
649976170	232	29.31	1	223	10	237	3.0e-23	102	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
649976171	333	30.12	1	331	1	341	3.0e-46	178	COG0673	Predicted dehydrogenase	342
649976172	191	22.4	7	184	2	174	2.0e-12	65.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649976173	403	44.58	15	397	3	408	2.0e-112	399	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archeal type	408
649976174	455	20.16	41	411	3	342	1.0e-25	111	COG0673	Predicted dehydrogenase	342
649976175	345	36.4	47	324	15	275	4.0e-47	182	COG3386	Sugar lactone lactonase YvrE	307
649976179	280	26.32	3	252	1	262	2.0e-33	136	COG1082	Sugar phosphate isomerase/epimerase	274
649976182	418	22.14	1	416	1	380	2.0e-44	173	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
649976185	302	27.05	1	278	5	295	2.0e-61	229	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
649976190	420	21.29	1	398	8	357	2.0e-19	90.1	COG2232	Predicted ATP-dependent carboligase, ATP-grasp superfamily	389
649976191	165	62.8	1	164	1	164	2.0e-57	214	COG1795	Formaldehyde-activating enzyme nesessary for methanogenesis	170
649976194	301	49.64	22	298	7	276	7.0e-89	320	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
649976195	444	32.3	19	428	6	382	2.0e-65	243	COG0247	Fe-S oxidoreductase	388
649976197	785	43.65	14	762	3	733	0.0e+00	702	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
649976198	639	48.28	4	639	1	635	0.0e+00	778	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
649976199	189	33.15	1	168	1	182	2.0e-28	118	COG0717	Deoxycytidine triphosphate deaminase	183
649976207	391	38.29	40	379	11	347	3.0e-57	215	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649976208	370	27.24	68	331	27	287	3.0e-32	132	COG0657	Acetyl esterase/lipase	312
649976209	491	21.1	32	359	79	387	2.0e-08	53.9	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
649976211	271	26.79	11	122	9	117	4.0e-08	52.3	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
649976212	433	45.24	52	429	127	498	2.0e-111	396	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649976213	160	25.66	9	160	4	143	5.0e-14	70.6	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
649976216	293	32.87	12	288	7	293	4.0e-41	161	COG2040	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)	300
649976217	528	33.58	1	526	1	487	6.0e-79	288	COG0168	Trk-type K+ transport system, membrane component	499
649976218	264	24.49	23	213	25	213	1.0e-18	87.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
649976220	354	55.38	25	349	14	325	2.0e-92	332	COG4864	Uncharacterized protein YqfA, UPF0365 family	328
649976222	400	26.58	30	383	3	380	9.0e-33	134	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649976223	434	21.55	63	350	3	282	4.0e-17	83	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649976224	543	17.21	176	405	19	250	1.0e-07	51.9	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
649976225	540	33.7	13	537	8	542	2.0e-83	303	COG2985	Uncharacterized membrane protein YbjL, putative transporter	544
649976226	429	39.58	1	425	3	390	1.0e-117	417	COG0448	ADP-glucose pyrophosphorylase	393
649976228	381	42.54	18	372	3	353	3.0e-100	358	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
649976229	227	20.42	22	212	1	170	2.0e-04	39.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649976232	577	55.17	1	347	2	345	9.0e-123	434	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
649976233	152	30.71	1	127	1	127	4.0e-16	77.6	COG1516	Flagellin-specific chaperone FliS	132
649976234	915	23.27	532	901	93	473	2.0e-27	118	COG1345	Flagellar capping protein FliD	483
649976237	1391	26.21	24	298	5	285	1.0e-09	60	COG0457	Tetratricopeptide (TPR) repeat	291
649976238	654	29.3	40	303	5	277	1.0e-13	71.9	COG0457	Tetratricopeptide (TPR) repeat	291
649976240	558	33.21	9	263	2	274	3.0e-41	163	COG0515	Serine/threonine protein kinase	384
649976241	179	56.25	6	165	7	166	3.0e-48	184	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
649976246	332	29.03	132	316	87	329	1.0e-22	100	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
649976247	166	56.62	32	166	46	181	1.0e-38	152	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
649976248	292	17.89	78	263	16	204	4.0e-09	55.7	COG5012	Methanogenic corrinoid protein MtbC1	227
649976249	496	29.53	3	255	2	248	2.0e-26	113	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
649976252	273	26.43	1	268	3	271	6.0e-30	124	COG1082	Sugar phosphate isomerase/epimerase	274
649976254	290	20.98	113	282	7	211	1.0e-06	47.6	COG2755	Lysophospholipase L1 or related esterase	216
649976255	568	32.66	180	568	11	405	1.0e-69	257	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
649976257	575	45	239	553	23	342	3.0e-76	279	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
649976259	125	54.55	2	78	1	76	1.0e-24	104	COG0228	Ribosomal protein S16	87
649976260	229	50	1	220	1	218	3.0e-82	298	COG0336	tRNA G37 N-methylase TrmD	240
649976261	129	54.46	6	117	4	115	5.0e-31	126	COG0335	Ribosomal protein L19	115
649976262	135	41.23	19	131	4	112	2.0e-24	104	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
649976263	153	62.16	14	124	1	111	1.0e-44	172	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
649976272	453	22.1	39	394	3	310	3.0e-30	126	COG0673	Predicted dehydrogenase	342
649976273	454	27.13	1	434	2	414	2.0e-35	143	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
649976276	474	25.47	20	427	1	474	3.0e-51	196	COG3119	Arylsulfatase A or related enzyme	475
649976282	182	25.66	1	152	2	136	5.0e-18	84.5	COG1943	REP element-mobilizing transposase RayT	136
649976284	343	36.39	1	337	1	285	8.0e-70	257	COG0191	Fructose/tagatose bisphosphate aldolase	286
649976287	288	25.57	19	278	8	229	6.0e-34	138	COG3253	Chlorite dismutase	230
649976304	569	30.42	1	356	35	399	2.0e-52	200	COG1061	Superfamily II DNA or RNA helicase	442
649976332	156	26.09	40	147	36	133	1.0e-06	46.2	COG5005	Mu-like prophage protein gpG	140
649976360	1558	34.48	1	902	3	795	0.0e+00	686	COG1201	Lhr-like helicase	814
649976369	515	16.46	76	450	11	399	1.0e-03	38.3	COG2211	Na+/melibiose symporter or related transporter	467
649976372	443	33.7	10	442	7	448	5.0e-86	311	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
649976373	396	40.86	9	396	1	393	8.0e-98	350	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
649976382	209	47.78	1	202	4	205	1.0e-44	173	COG2860	Uncharacterized membrane protein YeiH	209
649976383	382	34.6	39	375	1	334	5.0e-57	215	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
649976384	351	29.39	1	329	2	314	3.0e-40	159	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649976385	438	20.37	38	398	3	342	3.0e-25	109	COG0673	Predicted dehydrogenase	342
649976391	562	34.09	1	394	1	392	5.0e-45	176	COG0475	Kef-type K+ transport system, membrane component KefB	397
649976395	194	39.67	3	183	2	185	2.0e-38	151	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
649976396	669	41.33	4	577	50	635	0.0e+00	521	COG2943	Membrane glycosyltransferase	736
649976398	535	36.78	46	515	45	524	4.0e-97	349	COG3131	Periplasmic glucans biosynthesis protein	534
649976399	556	32.25	52	388	6	327	1.0e-44	174	COG0642	Signal transduction histidine kinase	336
649976402	583	32.15	11	568	6	591	1.0e-100	360	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
649976405	307	41.8	8	298	6	314	2.0e-82	299	COG0275	16S rRNA C1402 N4-methylase RsmH	314
649976409	497	29.05	32	464	1	432	3.0e-49	189	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
649976412	315	45.39	24	315	8	300	3.0e-87	315	COG4974	Site-specific recombinase XerD	300
649976413	374	47.61	6	374	17	390	7.0e-121	427	COG0372	Citrate synthase	390
649976415	164	51.3	11	164	2	152	2.0e-46	178	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
649976416	205	24.87	1	187	1	188	1.0e-16	80.1	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
649976417	369	60.43	1	369	1	369	0.0e+00	485	COG0686	Alanine dehydrogenase	371
649976419	462	44.85	14	448	4	411	7.0e-111	394	COG2262	50S ribosomal subunit-associated GTPase HflX	411
649976420	574	35.84	5	560	3	501	1.0e-118	420	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
649976421	119	13.98	27	118	24	116	9.0e-06	42.3	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
649976423	929	40.08	258	508	97	336	1.0e-43	172	COG0642	Signal transduction histidine kinase	336
649976425	444	41.34	4	432	2	428	2.0e-111	396	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
649976427	474	24.74	17	443	20	489	8.0e-66	244	COG3104	Dipeptide/tripeptide permease	498
649976430	332	26.28	7	316	7	271	1.0e-29	123	COG1082	Sugar phosphate isomerase/epimerase	274
649976432	92	41.77	8	86	1	75	8.0e-12	62.2	COG0238	Ribosomal protein S18	75
649976433	375	28.81	57	294	1	234	4.0e-35	142	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
649976434	448	28.42	45	422	41	409	5.0e-42	165	COG5379	S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase	414
649976436	393	16.37	5	362	4	377	9.0e-13	68.5	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649976437	198	35.29	53	170	18	134	2.0e-15	75.8	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
649976438	193	35.53	3	189	2	184	2.0e-26	112	COG0693	Putative intracellular protease/amidase	188
649976439	308	19.17	1	308	3	337	6.0e-16	78.4	COG0673	Predicted dehydrogenase	342
649976440	240	30.53	1	224	4	214	2.0e-34	139	COG2121	Uncharacterized conserved protein, lysophospholipid acyltransferase (LPLAT) superfamily	214
649976441	123	54.84	1	123	1	123	3.0e-34	137	COG4401	Chorismate mutase	125
649976442	577	36.58	35	576	1	553	0.0e+00	475	COG3961	TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase	557
649976443	487	29.91	1	430	9	432	5.0e-74	272	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
649976446	347	34.48	1	347	4	339	3.0e-83	302	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
649976448	246	51.98	1	241	1	245	2.0e-84	305	COG4422	Bacteriophage protein gp37	250
649976449	260	27.2	6	126	2	123	1.0e-14	74	COG3293	Transposase	124
649976450	353	19.82	30	342	5	305	2.0e-10	60.8	COG3021	Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily	309
649976451	300	26.41	22	298	1	281	6.0e-24	104	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649976452	410	42.24	11	403	7	387	4.0e-100	358	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
649976453	393	26.34	25	389	29	377	5.0e-47	182	COG0006	Xaa-Pro aminopeptidase	384
649976454	353	45.14	4	353	1	304	1.0e-82	299	COG0492	Thioredoxin reductase	305
649976456	505	40.67	3	503	2	464	0.0e+00	484	COG0215	Cysteinyl-tRNA synthetase	464
649976460	209	23.28	3	186	33	219	2.0e-06	46	COG1266	Membrane protease YdiL, CAAX protease family	226
649976463	508	34.23	104	361	84	334	4.0e-38	153	COG0642	Signal transduction histidine kinase	336
649976467	399	46.95	13	382	25	399	2.0e-107	382	COG0513	Superfamily II DNA and RNA helicase	513
649976468	656	49.1	52	656	1	592	0.0e+00	601	COG0465	ATP-dependent Zn proteases	596
649976470	216	32.16	17	214	4	191	2.0e-27	116	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
649976471	136	29.46	8	130	15	142	1.0e-07	48.9	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
649976472	168	52.29	17	168	1	153	4.0e-52	197	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
649976474	611	28.38	1	607	1	540	4.0e-75	276	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
649976475	110	40.74	4	110	3	110	7.0e-19	85.7	COG0607	Rhodanese-related sulfurtransferase	110
649976476	331	26.21	1	322	1	315	4.0e-34	138	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649976477	162	50.69	10	152	4	147	1.0e-46	179	COG0698	Ribose 5-phosphate isomerase RpiB	151
649976479	247	26.99	6	216	5	228	9.0e-26	110	COG0300	Short-chain dehydrogenase	265
649976483	165	33.61	33	151	7	123	2.0e-10	59.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
649976484	359	23.39	47	294	10	244	1.0e-05	44.6	COG0730	Uncharacterized membrane protein YfcA	258
649976485	564	21.72	123	539	3	442	2.0e-19	91.4	COG1538	Outer membrane protein TolC	457
649976502	337	33.63	8	337	2	342	3.0e-60	225	COG0673	Predicted dehydrogenase	342
649976505	146	32.85	2	132	5	140	1.0e-10	59.2	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
649976506	563	27.27	88	186	29	124	2.0e-07	51.4	COG0526	Thiol-disulfide isomerase or thioredoxin	127
649976507	753	18.71	189	453	2	285	3.0e-09	57.4	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
649976508	631	37.37	286	579	7	298	3.0e-54	207	COG0616	Periplasmic serine protease, ClpP class	317
649976509	972	36.93	172	967	1	743	0.0e+00	617	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
649976510	224	20.36	13	220	7	221	4.0e-05	41.9	COG1994	Zn-dependent protease (includes SpoIVFB)	230
649976513	417	30.09	279	391	18	124	7.0e-09	55.7	COG0526	Thiol-disulfide isomerase or thioredoxin	127
649976514	702	45.44	6	691	9	682	0.0e+00	731	COG0339	Zn-dependent oligopeptidase	683
649976515	231	29.65	6	229	4	226	3.0e-36	145	COG5587	Uncharacterized conserved protein, DUF2461 family	228
649976528	184	41.62	15	182	5	177	3.0e-34	138	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
649976529	486	23.79	24	439	1	458	5.0e-36	146	COG3119	Arylsulfatase A or related enzyme	475
649976533	268	28	4	248	3	234	2.0e-20	93.1	COG1891	Uncharacterized protein, UPF0264 family	235
649976534	618	61.31	20	615	2	598	0.0e+00	878	COG1217	Predicted membrane GTPase involved in stress response	603
649976535	463	51.1	1	453	1	454	0.0e+00	515	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
649976536	401	45.04	1	400	1	404	2.0e-104	372	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
649976538	247	49.77	4	222	2	222	1.0e-72	266	COG1136	ABC-type lipoprotein export system, ATPase component	226
649976539	264	36.47	11	264	7	257	8.0e-44	170	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
649976540	167	24.09	8	140	13	148	2.0e-08	52.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
649976543	309	44.63	1	298	5	300	3.0e-86	312	COG4974	Site-specific recombinase XerD	300
649976545	342	38.48	11	330	6	326	8.0e-60	224	COG0714	MoxR-like ATPase	329
649976547	363	36.51	47	360	3	293	4.0e-69	255	COG1131	ABC-type multidrug transport system, ATPase component	293
649976549	258	29.91	1	234	1	217	6.0e-24	104	COG1411	Uncharacterized protein related to proFAR isomerase (HisA)	229
649976550	401	31.37	6	375	1	361	1.0e-57	217	COG0349	Ribonuclease D	361
649976553	367	23.4	11	328	2	305	3.0e-20	93.1	COG3021	Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily	309
649976554	482	27.62	26	472	16	455	7.0e-55	208	COG0534	Na+-driven multidrug efflux pump	455
649976555	167	47.52	57	157	11	111	4.0e-30	124	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
649976556	713	42	48	709	2	648	0.0e+00	605	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
649976557	217	24.49	17	212	20	210	9.0e-17	80.4	COG0811	Biopolymer transport protein ExbB/TolQ	216
649976560	285	28.57	77	271	11	205	2.0e-23	103	COG0811	Biopolymer transport protein ExbB/TolQ	216
649976561	158	22.86	12	151	15	130	7.0e-08	50.2	COG0848	Biopolymer transport protein ExbD	137
649976562	166	24.09	1	137	2	119	2.0e-08	52.5	COG0848	Biopolymer transport protein ExbD	137
649976563	193	54.69	1	192	3	189	9.0e-75	272	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
649976564	499	48.69	5	497	3	498	0.0e+00	558	COG1129	ABC-type sugar transport system, ATPase component	500
649976565	141	30.53	8	134	7	131	9.0e-10	56.1	COG3607	Predicted lactoylglutathione lyase	133
649976566	569	34.08	73	367	1	311	4.0e-44	173	COG0515	Serine/threonine protein kinase	384
649976567	485	41.84	10	484	4	477	0.0e+00	476	COG0469	Pyruvate kinase	477
649976569	254	45.53	1	243	4	248	8.0e-55	207	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
649976570	367	36.6	3	361	6	381	7.0e-73	267	COG0006	Xaa-Pro aminopeptidase	384
649976571	174	34.87	22	173	1	140	2.0e-21	95.5	COG0511	Biotin carboxyl carrier protein	140
649976573	343	44.95	1	324	3	313	1.0e-84	307	COG0205	6-phosphofructokinase	347
649976575	171	37.35	5	167	2	166	3.0e-36	144	COG0703	Shikimate kinase	172
649976576	661	32.31	131	481	36	392	2.0e-48	187	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
649976577	512	51.57	4	414	1	408	2.0e-125	442	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
649976582	317	38.58	5	317	6	329	1.0e-67	250	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
649976583	299	26.42	34	278	15	273	4.0e-26	112	COG3386	Sugar lactone lactonase YvrE	307
649976584	301	23.79	26	288	54	297	2.0e-16	80	COG2382	Enterochelin esterase or related enzyme	299
649976585	378	28.03	85	373	5	263	2.0e-23	103	COG0575	CDP-diglyceride synthetase	265
649976586	322	53.82	1	319	2	340	2.0e-126	445	COG1089	GDP-D-mannose dehydratase	345
649976587	599	59.27	96	528	3	431	0.0e+00	619	COG0422	Thiamine biosynthesis protein ThiC	432
649976588	423	24.44	9	403	6	386	6.0e-36	145	COG0644	Dehydrogenase (flavoprotein)	396
649976590	450	42.76	1	449	1	444	2.0e-117	416	COG1160	Predicted GTPases	444
649976591	359	51.92	1	359	3	365	6.0e-123	434	COG1932	Phosphoserine aminotransferase	365
649976593	341	39.41	5	337	3	328	5.0e-70	258	COG3380	Predicted NAD/FAD-dependent oxidoreductase	331
649976594	321	20.48	8	172	7	169	4.0e-06	45.7	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
649976598	311	19.7	90	287	1	195	6.0e-03	35.1	COG1226	Voltage-gated potassium channel Kch	212
649976599	322	24.19	1	265	2	275	2.0e-22	100	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
649976601	162	23.18	1	141	11	156	3.0e-08	51.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
649976602	122	20.34	4	121	2	116	5.0e-05	40	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
649976604	445	19.36	78	396	45	356	1.0e-10	61.4	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649976607	171	21.85	12	159	4	152	9.0e-11	59.9	COG1406	Chemotaxis protein CheX, a CheY~P-specific phosphatase	153
649976608	454	30.41	106	397	49	343	3.0e-42	166	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
649976609	230	33.79	13	230	4	220	1.0e-35	143	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
649976610	493	42.63	1	491	1	481	0.0e+00	487	COG0297	Glycogen synthase	487
649976613	473	32.05	31	472	9	434	1.0e-73	270	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
649976615	287	35.34	7	280	1	281	2.0e-56	212	COG0061	NAD kinase	281
649976616	261	33.89	1	237	2	206	6.0e-26	111	COG0705	Membrane associated serine protease, rhomboid family	228
649976617	84	40	1	84	1	73	2.0e-18	83.8	COG0254	Ribosomal protein L31	75
649976618	358	54.24	1	352	5	358	1.0e-128	453	COG0216	Protein chain release factor A	363
649976619	309	42.25	25	308	2	278	1.0e-67	250	COG2890	Methylase of polypeptide chain release factors	280
649976620	447	57.31	1	421	1	421	0.0e+00	539	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
649976621	588	58.32	2	584	1	582	0.0e+00	847	COG0173	Aspartyl-tRNA synthetase	585
649976622	259	35.52	1	256	1	257	2.0e-49	189	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
649976623	303	24.52	16	294	9	319	6.0e-38	151	COG0280	Phosphotransacetylase	327
649976624	137	26.79	22	128	27	138	6.0e-11	60	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
649976626	344	26.79	56	329	36	297	1.0e-13	71.1	COG3547	Transposase	303
649976629	283	49.24	14	273	4	261	5.0e-75	274	COG0294	Dihydropteroate synthase	274
649976630	311	27.1	70	308	12	270	7.0e-15	74.9	COG1082	Sugar phosphate isomerase/epimerase	274
649976633	572	34.58	166	566	54	439	2.0e-55	211	COG2610	H+/gluconate symporter or related permease	442
649976634	614	26.24	65	588	7	458	5.0e-72	265	COG1109	Phosphomannomutase	464
649976636	224	31.79	26	215	60	254	3.0e-26	112	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
649976637	322	40.94	1	315	1	308	1.0e-61	230	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649976638	316	36.88	4	313	1	314	6.0e-61	227	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649976639	336	29.65	2	335	1	313	9.0e-54	204	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649976640	290	56.1	3	289	1	284	2.0e-108	385	COG1209	dTDP-glucose pyrophosphorylase	286
649976641	282	30.3	52	261	74	298	5.0e-26	111	COG0657	Acetyl esterase/lipase	312
649976642	546	50.48	1	314	2	313	4.0e-88	319	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
649976646	209	45.55	7	197	4	190	1.0e-53	203	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
649976647	581	28.53	244	573	35	363	5.0e-37	149	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
649976649	260	27.2	6	126	2	123	1.0e-14	74	COG3293	Transposase	124
649976653	334	26.71	3	146	2	147	6.0e-09	55.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
649976657	192	19.5	5	163	3	136	3.0e-07	48.7	COG1943	REP element-mobilizing transposase RayT	136
649976659	458	27.02	3	456	2	409	1.0e-59	224	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
649976660	723	22.3	21	422	6	395	6.0e-18	86.6	COG1668	ABC-type Na+ efflux pump, permease component	407
649976661	248	42.11	1	246	4	250	4.0e-65	241	COG1131	ABC-type multidrug transport system, ATPase component	293
649976664	218	30.32	2	217	1	219	1.0e-34	140	COG0569	Trk K+ transport system, NAD-binding component	225
649976665	447	29.04	5	443	56	497	7.0e-52	198	COG0168	Trk-type K+ transport system, membrane component	499
649976667	242	45.61	5	240	7	241	2.0e-68	252	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
649976668	168	17.36	7	150	3	137	1.0e-06	46.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
649976674	506	40.7	22	500	1	451	0.0e+00	496	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
649976675	1538	57.35	737	1222	4	481	0.0e+00	649	COG0069	Glutamate synthase domain 2	485
649976676	309	27.8	1	293	1	291	7.0e-36	144	COG0583	DNA-binding transcriptional regulator, LysR family	297
649976678	308	31.16	10	300	7	288	2.0e-39	156	COG1562	Phytoene/squalene synthetase	288
649976681	368	23.81	10	223	2	231	3.0e-12	66.1	COG3063	Tfp pilus assembly protein PilF	250
649976684	61	35.19	7	60	4	57	1.0e-05	41.8	COG3847	Flp pilus assembly protein, pilin Flp	58
649976685	162	56.6	4	162	1	157	1.0e-54	205	COG1225	Peroxiredoxin	157
649976686	112	44.44	10	108	5	103	7.0e-27	112	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
649976687	184	44.71	3	171	1	169	7.0e-45	173	COG0221	Inorganic pyrophosphatase	171
649976688	352	16.23	28	321	14	311	4.0e-16	79.4	COG3239	Fatty acid desaturase	343
649976689	613	58.87	11	612	1	603	0.0e+00	906	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
649976690	408	47.4	7	294	4	292	3.0e-88	318	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
649976696	331	49.7	2	331	1	329	4.0e-111	394	COG0240	Glycerol-3-phosphate dehydrogenase	329
649976697	293	30.73	10	214	9	205	2.0e-18	86.7	COG0705	Membrane associated serine protease, rhomboid family	228
649976698	332	35.02	64	319	5	240	3.0e-30	126	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
649976703	293	29.03	13	198	1	177	4.0e-22	98.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649976704	250	45.85	3	250	2	250	6.0e-45	174	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649976706	120	65.79	3	116	2	115	7.0e-44	169	COG4898	Uncharacterized protein	115
649976714	127	35.85	1	106	1	106	8.0e-22	95.9	COG2076	Multidrug transporter EmrE and related cation transporters	106
649976715	287	30.43	1	270	1	275	9.0e-33	134	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
649976716	203	41	1	199	3	196	1.0e-52	199	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
649976718	423	63.55	4	420	3	416	0.0e+00	623	COG0148	Enolase	423
649976722	259	71.26	1	254	1	254	7.0e-116	409	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
649976723	334	25	9	151	5	148	5.0e-08	52.4	COG2165	Type II secretory pathway, pseudopilin PulG	149
649976724	260	53.65	26	258	13	245	4.0e-81	294	COG0020	Undecaprenyl pyrophosphate synthase	245
649976728	302	33.8	27	301	22	305	2.0e-42	166	COG0668	Small-conductance mechanosensitive channel	316
649976731	345	29.13	6	331	55	385	4.0e-44	172	COG1459	Type II secretory pathway, component PulF	397
649976732	680	34.19	299	602	7	293	2.0e-44	174	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
649976733	247	18.83	1	223	3	166	1.0e-11	63.9	COG0622	Predicted phosphodiesterase	172
649976735	515	45.93	111	515	6	381	2.0e-124	439	COG2721	Altronate dehydratase	381
649976736	652	32.58	7	580	4	555	3.0e-90	326	COG0358	DNA primase (bacterial type)	568
649976737	590	48.42	270	580	31	342	1.0e-78	287	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
649976738	225	30.77	1	213	1	211	7.0e-27	114	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
649976739	502	26.87	34	457	4	474	9.0e-50	191	COG3119	Arylsulfatase A or related enzyme	475
649976740	330	20.66	63	313	10	259	3.0e-05	43	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
649976742	375	41.64	94	372	23	291	4.0e-74	272	COG1162	Putative ribosome biogenesis GTPase RsgA	301
649976746	341	27.41	1	134	3	133	5.0e-09	55.4	COG2165	Type II secretory pathway, pseudopilin PulG	149
649976748	260	49.8	5	258	1	253	2.0e-80	292	COG0134	Indole-3-glycerol phosphate synthase	254
649976749	194	25.13	5	184	9	195	3.0e-10	58.7	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
649976750	207	36.04	8	198	6	202	5.0e-32	130	COG4112	Predicted phosphoesterase, NUDIX family	203
649976752	347	32.5	9	311	6	316	3.0e-67	248	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
649976753	326	40.38	57	318	20	278	4.0e-56	212	COG1398	Fatty-acid desaturase	289
649976754	291	23.94	29	232	34	233	2.0e-07	50.3	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
649976756	376	40.8	28	352	1	322	6.0e-78	284	COG0042	tRNA-dihydrouridine synthase	323
649976758	528	50.82	164	526	55	420	8.0e-122	431	COG1158	Transcription termination factor Rho	422
649976761	226	26.32	1	225	3	219	1.0e-20	93.3	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
649976762	434	41.93	10	418	5	415	3.0e-103	368	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
649976763	392	63.14	1	380	2	388	0.0e+00	592	COG0192	S-adenosylmethionine synthetase	388
649976765	94	51.14	1	88	1	88	3.0e-09	53.8	COG0268	Ribosomal protein S20	88
649976768	435	32.32	8	432	4	408	9.0e-66	244	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
649976769	469	31.44	30	440	5	443	2.0e-68	253	COG3119	Arylsulfatase A or related enzyme	475
649976773	223	34.76	12	218	15	224	1.0e-34	139	COG0220	tRNA G46 methylase TrmB	227
649976777	498	24.75	1	492	1	497	4.0e-83	302	COG1070	Sugar (pentulose or hexulose) kinase	502
649976779	329	44.39	141	316	10	194	7.0e-34	138	COG1573	Uracil-DNA glycosylase	202
649976781	968	32.01	28	523	1	506	3.0e-73	270	COG0342	Preprotein translocase subunit SecD	506
649976782	126	28.57	21	118	2	96	3.0e-10	57.5	COG1862	Preprotein translocase subunit YajC	97
649976783	372	55.65	8	369	1	363	0.0e+00	490	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
649976784	497	40.3	19	480	3	436	9.0e-123	434	COG0621	tRNA A37 methylthiotransferase MiaB	437
649976786	189	38.93	1	131	1	131	7.0e-33	133	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
649976787	346	45.15	16	344	6	335	6.0e-103	367	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
649976794	260	27.2	6	126	2	123	1.0e-14	74	COG3293	Transposase	124
649976796	535	32.39	44	535	17	458	1.0e-78	287	COG5361	Uncharacterized conserved protein	458
649976797	182	26.01	1	147	4	176	4.0e-21	94.9	COG1335	Nicotinamidase-related amidase	205
649976798	231	44.29	14	223	1	206	1.0e-61	229	COG0177	Endonuclease III	211
649976808	240	26.52	9	227	11	235	2.0e-23	102	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
649976809	161	27.27	7	160	3	148	2.0e-12	65.1	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
649976811	125	37.5	4	123	2	121	6.0e-27	113	COG3682	Predicted transcriptional regulator	123
649976814	708	21.32	1	611	1	522	2.0e-40	161	COG3593	Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains	581
649976815	613	18.92	22	582	17	612	5.0e-20	92.9	COG0210	Superfamily I DNA or RNA helicase	655
649976817	741	33.65	77	381	2	286	1.0e-40	162	COG0515	Serine/threonine protein kinase	384
649976818	185	25.14	5	178	3	169	4.0e-05	41.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649976820	253	28.83	7	213	6	225	2.0e-30	126	COG0300	Short-chain dehydrogenase	265
649976821	318	22.68	53	318	7	256	3.0e-07	49.2	COG0730	Uncharacterized membrane protein YfcA	258
649976822	122	46.02	10	122	4	116	4.0e-29	120	COG1733	DNA-binding transcriptional regulator, HxlR family	120
649976825	260	27.2	6	126	2	123	1.0e-14	74	COG3293	Transposase	124
649976832	295	31.07	8	287	1	260	8.0e-34	137	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
649976836	260	27.2	6	126	2	123	1.0e-14	74	COG3293	Transposase	124
649976838	329	40	1	318	1	326	1.0e-72	266	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
649976839	228	16.86	9	145	1	172	3.0e-08	52.5	COG1335	Nicotinamidase-related amidase	205
649976840	341	32.76	225	340	3	118	1.0e-21	97.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649976854	433	23.13	13	422	21	405	1.0e-21	98	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
649976855	260	28	6	126	2	123	3.0e-15	75.9	COG3293	Transposase	124
649976856	189	34.57	4	186	12	194	8.0e-34	136	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
649976858	245	39.68	1	244	1	251	8.0e-43	167	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649976861	1054	21.05	12	195	8	215	7.0e-12	66.8	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
649976862	250	39.91	22	234	17	218	8.0e-42	163	COG2045	Phosphosulfolactate phosphohydrolase or related enzyme	230
649976863	137	36.62	1	135	7	148	9.0e-31	125	COG0781	Transcription termination factor NusB	151
649976864	156	54.97	3	152	2	152	4.0e-47	180	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
649976865	462	64.61	42	460	2	419	0.0e+00	658	COG1158	Transcription termination factor Rho	422
649976867	290	37.76	83	277	4	191	5.0e-37	148	COG0237	Dephospho-CoA kinase	201
649976868	397	52.99	1	397	2	393	2.0e-130	459	COG0126	3-phosphoglycerate kinase	395
649976874	321	24.48	34	320	35	322	3.0e-30	126	COG0598	Mg2+ and Co2+ transporter CorA	322
649976875	809	34.3	35	464	26	454	2.0e-70	261	COG5361	Uncharacterized conserved protein	458
649976879	368	28.23	230	348	4	127	4.0e-14	72.7	COG4639	Predicted kinase	168
649976885	625	22.3	7	300	14	268	2.0e-25	111	COG0863	DNA modification methylase	302
649976886	335	27.71	1	328	1	328	1.0e-34	140	COG1466	DNA polymerase III, delta subunit	334
649976887	245	45.81	1	155	2	155	3.0e-40	158	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
649976890	961	50.11	40	960	17	906	0.0e+00	1102	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
649976892	284	44.56	1	283	11	284	2.0e-59	222	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
649976893	2050	19.03	412	2048	174	1620	1.0e-89	326	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
649976896	356	44.07	28	347	11	329	2.0e-71	263	COG0714	MoxR-like ATPase	329
649976897	124	18.92	11	121	9	116	7.0e-06	42.7	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
649976899	436	37.24	13	436	36	457	1.0e-74	274	COG4325	Uncharacterized membrane protein	464
649976903	302	32.5	1	234	1	239	3.0e-39	155	COG1351	Thymidylate synthase ThyX	273
649976905	417	24.05	2	341	11	316	5.0e-28	119	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
649976906	770	43.94	16	650	2	640	0.0e+00	560	COG0210	Superfamily I DNA or RNA helicase	655
649976909	153	26.98	43	152	6	131	2.0e-13	68.4	COG3296	Uncharacterized conserved protein, Tic20 family	143
649976911	272	42.69	5	256	3	250	1.0e-61	230	COG3739	Uncharacterized membrane protein YoaT, DUF817 family	263
649976912	618	25.22	46	608	17	508	1.0e-57	217	COG0815	Apolipoprotein N-acyltransferase	518
649976913	411	41.48	1	402	6	401	6.0e-93	334	COG0303	Molybdopterin biosynthesis enzyme	404
649976917	662	27.05	125	648	43	560	2.0e-62	234	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
649976918	377	26.71	38	329	24	308	5.0e-27	115	COG3447	Integral membrane sensor domain MASE1	308
649976919	620	29.45	5	421	8	428	4.0e-40	160	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
649976922	271	35.47	8	264	4	244	4.0e-43	168	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
649976923	218	25.65	9	179	5	179	8.0e-05	40.7	COG0778	Nitroreductase	207
649976925	503	26.89	34	473	2	470	8.0e-57	214	COG3119	Arylsulfatase A or related enzyme	475
649976928	259	49.38	1	239	2	241	3.0e-82	298	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
649976929	157	33.33	9	154	8	153	2.0e-25	108	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
649976930	326	18.27	45	244	62	268	3.0e-04	39.5	COG1652	Nucleoid-associated protein YgaU, contains BON and LysM domains	269
649976931	768	23.37	26	751	3	724	4.0e-70	260	COG1033	Predicted exporter protein, RND superfamily	727
649976933	686	45.8	6	684	7	666	0.0e+00	714	COG1331	Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains	667
649976935	187	31.46	13	187	4	181	1.0e-25	109	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649976939	259	41.18	1	248	1	251	5.0e-43	168	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649976941	423	15.91	94	396	15	299	9.0e-07	48.6	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
649976942	1114	41.29	44	1091	13	1109	0.0e+00	1033	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
649976944	198	23.9	7	165	3	136	4.0e-09	54.9	COG1943	REP element-mobilizing transposase RayT	136
649976949	265	35.89	6	250	4	249	3.0e-48	185	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
649976950	409	60.67	1	150	1	150	2.0e-56	213	COG1017	Hemoglobin-like flavoprotein	150
649976951	140	31.16	1	135	2	139	5.0e-23	100	COG1959	DNA-binding transcriptional regulator, IscR family	150
649976953	414	21.43	120	398	14	296	7.0e-12	65.6	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649976954	323	25.56	38	263	44	300	7.0e-21	95.1	COG4188	Predicted dienelactone hydrolase	365
649976958	608	44.8	40	573	13	540	0.0e+00	471	COG0539	Ribosomal protein S1	541
649976959	295	23.02	157	282	21	136	2.0e-13	69.7	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
649976961	72	32.84	7	72	1	67	1.0e-07	48	COG1826	Sec-independent protein translocase protein TatA	94
649976962	99	25.32	2	79	1	79	1.0e-09	55	COG1826	Sec-independent protein translocase protein TatA	94
649976963	662	44.29	88	646	1	528	0.0e+00	679	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
649976964	204	30	38	194	28	194	4.0e-13	68.4	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
649976966	355	39.63	39	305	2	262	9.0e-51	194	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
649976967	151	45.26	12	148	9	144	3.0e-35	141	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
649976968	415	48.53	6	411	1	405	1.0e-128	453	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
649976969	515	26.08	24	440	3	365	3.0e-31	129	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649976970	1072	46.3	2	1039	1	1009	0.0e+00	982	COG0841	Multidrug efflux pump subunit AcrB	1009
649976971	414	46.05	10	399	6	434	5.0e-124	438	COG1570	Exonuclease VII, large subunit	440
649976972	120	44.59	4	77	1	74	3.0e-09	53.8	COG1722	Exonuclease VII small subunit	81
649976973	358	39.5	4	358	1	352	1.0e-78	287	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
649976975	106	57.55	1	106	1	106	5.0e-31	126	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
649976976	398	19.77	34	368	42	389	6.0e-11	62.3	COG3875	Nickel-dependent lactate racemase	423
649976977	202	32.98	4	191	1	181	6.0e-27	114	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649976980	350	41.64	35	327	2	289	1.0e-65	243	COG1533	DNA repair photolyase	297
649976983	108	26.61	1	108	9	117	7.0e-11	59.1	COG1917	Cupin domain protein related to quercetin dioxygenase	131
649976984	115	55.65	1	114	3	117	5.0e-36	142	COG3189	Uncharacterized conserved protein YeaO, DUF488 family	117
649976986	452	48.4	27	276	1	239	6.0e-84	305	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
649976990	472	41.75	1	472	1	443	2.0e-129	456	COG0174	Glutamine synthetase	443
649976991	145	32.59	9	137	1	135	3.0e-15	74.5	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
649976994	432	33.02	34	341	7	315	6.0e-51	195	COG4782	Esterase/lipase superfamily enzyme	377
649976995	81	28.57	5	74	3	78	4.0e-03	33.3	COG2929	Uncharacterized conserved protein, DUF497 family	93
649976999	497	28.36	43	464	3	448	4.0e-52	199	COG3119	Arylsulfatase A or related enzyme	475
649977002	513	45.92	1	500	3	496	0.0e+00	461	COG1070	Sugar (pentulose or hexulose) kinase	502
649977003	247	19.72	35	245	29	246	3.0e-12	65.5	COG4700	Uncharacterized protein	251
649977006	415	35.29	23	405	5	391	2.0e-88	319	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
649977009	474	37.19	2	393	1	387	4.0e-65	242	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
649977011	131	30.71	3	128	1	120	5.0e-13	66.7	COG3293	Transposase	124
649977013	1189	51.17	24	781	7	712	0.0e+00	813	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
649977016	401	22.1	33	380	1	332	8.0e-29	121	COG0673	Predicted dehydrogenase	342
649977017	266	36.08	1	255	3	253	2.0e-49	189	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
649977018	119	35.58	14	115	4	106	2.0e-18	84.6	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
649977025	631	18.75	83	339	1	267	3.0e-10	60.8	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
649977028	118	47.37	7	117	32	137	2.0e-26	110	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
649977029	140	42.14	1	139	1	137	1.0e-38	152	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
649977030	570	30.96	83	337	2	279	2.0e-38	154	COG0515	Serine/threonine protein kinase	384
649977031	167	28.48	17	167	33	181	6.0e-15	74	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649977038	164	25.64	45	157	38	150	1.0e-07	49.5	COG3091	Predicted Zn-dependent metalloprotease, SprT family	156
649977040	373	14.89	32	354	8	273	3.0e-05	43.6	COG1075	Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold	336
649977042	423	31.05	10	409	27	410	5.0e-64	238	COG2124	Cytochrome P450	411
649977044	121	62.5	9	119	3	114	5.0e-37	146	COG4898	Uncharacterized protein	115
649977047	1075	36.82	2	1009	1	1009	0.0e+00	888	COG0841	Multidrug efflux pump subunit AcrB	1009
649977050	221	27.8	1	205	1	193	1.0e-13	70.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649977059	310	33.57	40	297	5	283	3.0e-40	159	COG4974	Site-specific recombinase XerD	300
649977060	156	20.97	4	65	3	64	2.0e-03	35.3	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
649977061	313	36.57	10	309	24	326	4.0e-51	194	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
649977065	301	37.46	2	301	6	305	3.0e-49	189	COG4227	Antirestriction protein ArdC	316
649977068	260	30.56	1	238	2	253	1.0e-39	157	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
649977071	650	21.41	6	500	2	499	4.0e-20	93.5	COG4928	Predicted P-loop ATPase, KAP-like	646
649977074	510	40.16	14	498	4	475	2.0e-101	363	COG0286	Type I restriction-modification system, DNA methylase subunit	489
649977076	1058	26.46	76	1010	55	952	7.0e-98	352	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
649977077	249	27.51	15	243	1	213	2.0e-31	129	COG1451	Predicted metal-dependent hydrolase	223
649977084	131	30.71	3	128	1	120	5.0e-13	66.7	COG3293	Transposase	124
649977089	232	21.43	6	225	17	281	3.0e-17	82.3	COG0863	DNA modification methylase	302
649977095	166	31.61	6	152	21	161	6.0e-15	73.9	COG3236	Predicted NAD-dependent protein-ADP-ribosyltransferase YbiA, DUF1768 family	162
649977097	427	19.58	10	198	16	203	4.0e-12	66.5	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
649977098	677	19.11	17	240	6	220	2.0e-12	67.9	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
649977104	471	26.34	70	253	38	216	7.0e-10	59.2	COG3063	Tfp pilus assembly protein PilF	250
649977109	249	30.58	6	209	2	160	2.0e-27	116	COG4185	Predicted ABC-type ATPase	187
649977112	217	38.28	1	208	1	202	3.0e-52	198	COG1182	FMN-dependent NADH-azoreductase	202
649977115	142	34.04	33	126	1	94	2.0e-09	54.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
649977117	598	31.25	10	292	2	298	6.0e-45	175	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
649977118	138	40.56	1	137	2	138	5.0e-31	126	COG0394	Protein-tyrosine-phosphatase	139
649977119	1108	46.58	744	1108	110	457	7.0e-104	372	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649977120	339	48.48	12	339	1	322	7.0e-102	364	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
649977121	358	40.53	1	335	1	333	3.0e-107	381	COG0836	Mannose-1-phosphate guanylyltransferase	333
649977125	603	36.58	1	579	1	559	6.0e-105	375	COG1966	Carbon starvation protein CstA	575
649977127	69	50.82	1	61	1	61	9.0e-14	68.4	COG1551	sRNA-binding carbon storage regulator CsrA	73
649977128	859	23.91	2	277	1	271	3.0e-16	80.9	COG1344	Flagellin and related hook-associated protein FlgL	360
649977135	429	34.34	130	425	67	359	5.0e-68	252	COG0337	3-dehydroquinate synthetase	360
649977136	143	35.88	1	128	4	133	1.0e-27	115	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
649977137	475	20.2	12	466	3	481	5.0e-25	109	COG1233	Phytoene dehydrogenase-related protein	487
649977150	752	30.47	111	357	3	257	1.0e-35	145	COG1216	Glycosyltransferase, GT2 family	305
649977151	326	23.62	15	257	2	247	1.0e-14	74.4	COG1216	Glycosyltransferase, GT2 family	305
649977152	652	32.45	118	641	32	544	7.0e-101	361	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
649977154	186	29.73	9	155	7	136	9.0e-15	73.4	COG0262	Dihydrofolate reductase	167
649977155	224	33.66	4	200	3	200	1.0e-34	140	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
649977156	195	25.97	10	188	9	188	6.0e-20	90.8	COG3224	Antibiotic biosynthesis monooxygenase (ABM) superfamily enzyme	195
649977157	165	22.67	1	146	4	153	1.0e-10	59.2	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
649977158	222	43.98	3	218	2	207	2.0e-28	119	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
649977159	365	36.21	14	365	12	367	6.0e-49	188	COG0387	Ca2+/H+ antiporter	368
649977160	239	21.17	19	239	18	233	1.0e-14	73.8	COG0670	Integral membrane protein, interacts with FtsH	233
649977161	347	29.94	7	346	1	339	2.0e-46	179	COG0673	Predicted dehydrogenase	342
649977162	445	21.33	41	390	3	314	3.0e-29	123	COG0673	Predicted dehydrogenase	342
649977163	341	14.33	49	338	32	284	5.0e-07	48.8	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
649977165	267	25.19	3	252	1	257	5.0e-07	48.5	COG0730	Uncharacterized membrane protein YfcA	258
649977168	138	49.23	1	127	3	130	3.0e-32	131	COG1970	Large-conductance mechanosensitive channel	130
649977169	295	23.6	41	284	58	305	9.0e-27	114	COG0657	Acetyl esterase/lipase	312
649977170	434	66.67	7	434	6	426	0.0e+00	668	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
649977172	183	21.59	8	180	11	171	2.0e-14	71.9	COG3216	Uncharacterized conserved protein, DUF2062 family	184
649977174	749	25.61	445	726	9	288	1.0e-30	128	COG0657	Acetyl esterase/lipase	312
649977174	749	30.04	26	446	2	451	4.0e-57	216	COG3119	Arylsulfatase A or related enzyme	475
649977175	241	21.4	4	228	8	243	7.0e-11	61.2	COG1360	Flagellar motor protein MotB	244
649977177	701	45.25	21	680	11	669	0.0e+00	663	COG1200	RecG-like helicase	677
649977179	279	39.93	1	279	1	273	4.0e-61	228	COG0266	Formamidopyrimidine-DNA glycosylase	273
649977181	141	24.19	1	62	2	63	9.0e-07	46.1	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
649977189	475	25.41	1	461	1	465	7.0e-53	201	COG3119	Arylsulfatase A or related enzyme	475
649977190	343	43.69	21	342	11	333	4.0e-91	328	COG0502	Biotin synthase or related enzyme	335
649977191	342	33.43	1	340	1	350	1.0e-70	259	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
649977199	255	35.83	1	250	1	249	2.0e-42	165	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649977200	471	46.54	1	471	1	443	0.0e+00	500	COG0174	Glutamine synthetase	443
649977202	126	35.35	28	126	1	90	3.0e-07	47.8	COG0776	Bacterial nucleoid DNA-binding protein	94
649977203	70	51.72	1	58	1	58	5.0e-14	69.2	COG1551	sRNA-binding carbon storage regulator CsrA	73
649977230	228	26.7	5	219	1	198	9.0e-28	117	COG0338	Site-specific DNA-adenine methylase	274
649977245	1251	21.31	49	386	15	361	8.0e-03	37.3	COG1474	Cdc6-related protein, AAA superfamily ATPase	366
649977252	300	36.74	2	299	6	304	6.0e-51	194	COG4227	Antirestriction protein ArdC	316
649977255	318	31.72	10	310	18	325	1.0e-49	190	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
649977257	303	30.82	20	296	7	291	3.0e-38	152	COG4974	Site-specific recombinase XerD	300
649977260	150	20.87	34	148	5	118	2.0e-06	45.2	COG2044	Predicted peroxiredoxin	120
649977275	194	27.03	10	194	5	181	1.0e-14	72.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649977276	569	31.65	81	335	2	279	4.0e-37	149	COG0515	Serine/threonine protein kinase	384
649977277	607	25.86	10	181	3	162	2.0e-12	68.3	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
649977281	458	23.47	5	448	7	457	4.0e-20	93.1	COG5511	Bacteriophage capsid protein	492
649977287	343	42.23	1	245	6	252	4.0e-57	215	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
649977290	306	28.52	53	306	4	246	1.0e-32	133	COG0356	FoF1-type ATP synthase, membrane subunit a	246
649977292	233	30.19	74	232	3	161	7.0e-21	94.2	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
649977293	214	32.16	23	193	7	177	8.0e-28	117	COG0712	FoF1-type ATP synthase, delta subunit	178
649977294	517	64.04	1	495	1	495	0.0e+00	773	COG0056	FoF1-type ATP synthase, alpha subunit	504
649977295	291	39.37	5	291	1	287	1.0e-67	250	COG0224	FoF1-type ATP synthase, gamma subunit	287
649977296	481	67.65	8	480	2	467	0.0e+00	749	COG0055	FoF1-type ATP synthase, beta subunit	468
649977297	135	29.69	5	130	2	129	4.0e-18	83.8	COG0355	FoF1-type ATP synthase, epsilon subunit	135
649977299	225	33.82	44	111	6	73	2.0e-04	39.5	COG3655	DNA-binding transcriptional regulator, XRE family	73
649977301	128	34.44	4	89	1	90	1.0e-09	55.5	COG3293	Transposase	124
649977303	1704	22.05	726	1108	62	399	2.0e-16	83.1	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
649977305	310	21.92	32	291	46	284	4.0e-11	62.4	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
649977309	343	26.79	56	329	36	297	2.0e-13	70.7	COG3547	Transposase	303
649977314	245	27.43	6	165	7	178	2.0e-11	62.8	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
649977318	361	34.07	21	330	15	306	6.0e-53	201	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
649977319	321	46.01	3	314	2	307	2.0e-90	326	COG0223	Methionyl-tRNA formyltransferase	307
649977320	198	42.57	1	147	4	151	1.0e-40	159	COG0242	Peptide deformylase	168
649977321	553	36.76	8	553	6	553	0.0e+00	534	COG0423	Glycyl-tRNA synthetase (class II)	558
649977323	390	30.81	1	380	2	381	1.0e-75	277	COG0763	Lipid A disaccharide synthetase	381
649977324	295	40.22	1	274	1	271	2.0e-75	275	COG0648	Endonuclease IV	280
649977327	391	26.77	1	384	3	381	4.0e-36	145	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649977328	1524	20.53	451	752	15	320	1.0e-09	59.8	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649977329	1335	25.38	127	428	2	323	2.0e-33	139	COG0515	Serine/threonine protein kinase	384
649977331	326	31.2	5	121	4	127	2.0e-08	53.9	COG2165	Type II secretory pathway, pseudopilin PulG	149
649977332	1006	17.95	1	418	1	395	2.0e-04	41.9	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
649977333	461	43.98	8	461	10	435	0.0e+00	498	COG0017	Aspartyl/asparaginyl-tRNA synthetase	435
649977345	1195	17.32	732	1008	38	336	5.0e-08	54.3	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
649977347	365	28.23	1	328	3	317	3.0e-32	132	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
649977348	506	53.68	5	503	1	500	0.0e+00	622	COG1129	ABC-type sugar transport system, ATPase component	500
649977349	496	48.28	1	494	3	481	0.0e+00	588	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
649977350	562	39.43	272	542	6	268	4.0e-64	239	COG0171	NH3-dependent NAD+ synthetase	268
649977352	302	31.93	16	294	9	247	5.0e-57	214	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
649977358	489	29.52	27	430	2	449	3.0e-57	216	COG3119	Arylsulfatase A or related enzyme	475
649977359	171	37.59	25	163	20	159	7.0e-19	86.9	COG1267	Phosphatidylglycerophosphatase A	160
649977362	344	26.79	56	329	36	297	1.0e-13	71.1	COG3547	Transposase	303
649977369	269	52.83	1	264	1	259	8.0e-100	356	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
649977370	289	47.73	26	287	13	264	5.0e-78	284	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
649977371	241	30.66	13	216	1	204	2.0e-30	125	COG0602	Organic radical activating enzyme	212
649977374	263	47.18	15	259	4	248	7.0e-58	217	COG1691	NCAIR mutase (PurE)-related protein	254
649977375	315	26.58	1	312	10	307	1.0e-40	160	COG2017	Galactose mutarotase or related enzyme	308
649977380	275	46.37	19	263	4	250	5.0e-73	267	COG0024	Methionine aminopeptidase	255
649977381	561	21.85	192	485	7	275	7.0e-10	59.5	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649977382	440	32.82	170	428	105	363	2.0e-45	176	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
649977384	295	19.83	41	271	30	217	1.0e-05	44.3	COG3828	Type 1 glutamine amidotransferase (GATase1)-like domain	239
649977386	737	23.23	102	435	42	354	2.0e-15	78.3	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649977387	334	21.94	15	322	8	303	9.0e-20	91.2	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
649977388	250	41.41	1	223	2	226	3.0e-58	218	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
649977390	311	48.47	136	298	10	162	1.0e-41	163	COG1045	Serine acetyltransferase	194
649977391	477	26.27	70	477	21	426	8.0e-36	145	COG3746	Phosphate-selective porin	426
649977393	298	29.32	1	297	4	309	2.0e-33	136	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
649977394	364	34.65	68	267	1	197	9.0e-37	147	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
649977395	119	32.53	37	119	33	115	2.0e-07	47.7	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
649977397	324	37.7	13	258	7	239	1.0e-36	147	COG2035	Uncharacterized membrane protein	276
649977399	182	27.45	1	152	1	136	1.0e-18	86.5	COG1943	REP element-mobilizing transposase RayT	136
649977400	831	23.24	202	535	86	401	3.0e-17	84.3	COG1668	ABC-type Na+ efflux pump, permease component	407
649977401	254	42.91	1	247	1	243	3.0e-69	255	COG4555	ABC-type Na+ transport system, ATPase component NatA	245
649977402	395	49.48	4	388	2	387	7.0e-125	440	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
649977403	390	16.75	5	375	27	407	4.0e-04	39.3	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
649977406	372	22.77	6	371	4	377	3.0e-25	109	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649977408	394	25.51	1	386	1	377	5.0e-31	128	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649977410	327	30.94	9	309	2	310	4.0e-43	168	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649977411	366	68.51	14	354	2	343	0.0e+00	554	COG1089	GDP-D-mannose dehydratase	345
649977413	278	41.42	4	271	2	250	4.0e-77	281	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
649977419	174	27.06	3	166	4	173	2.0e-19	88.5	COG0431	NAD(P)H-dependent FMN reductase	184
649977422	680	39	1	544	3	558	0.0e+00	567	COG0143	Methionyl-tRNA synthetase	558
649977423	465	34.89	1	465	8	460	2.0e-105	376	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
649977425	485	29.04	145	414	32	299	2.0e-30	127	COG0668	Small-conductance mechanosensitive channel	316
649977426	415	34.38	5	406	11	420	1.0e-76	280	COG1253	Hemolysin or related protein, contains CBS domains	429
649977428	202	64.74	3	192	2	191	2.0e-78	285	COG0740	ATP-dependent protease ClpP, protease subunit	200
649977429	215	57.54	34	212	20	198	2.0e-64	238	COG0740	ATP-dependent protease ClpP, protease subunit	200
649977430	673	25.77	107	261	1	161	3.0e-07	50.8	COG0681	Signal peptidase I	166
649977431	279	23.36	12	261	11	268	6.0e-09	54.9	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
649977434	249	29.06	1	230	2	230	1.0e-26	113	COG1381	Recombinational DNA repair protein (RecF pathway)	251
649977436	360	34.95	70	357	4	289	5.0e-38	151	COG0382	4-hydroxybenzoate polyprenyltransferase	289
649977437	375	44.01	6	360	5	363	9.0e-105	373	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
649977439	136	30.43	9	131	3	136	4.0e-10	57.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
649977441	459	52.72	1	459	1	459	0.0e+00	547	COG0165	Argininosuccinate lyase	459
649977443	343	26.79	56	329	36	297	2.0e-13	70.7	COG3547	Transposase	303
649977445	296	47.77	73	295	41	225	7.0e-62	230	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
649977448	375	22.87	12	302	5	290	2.0e-21	96.7	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649977451	135	33.02	30	133	27	132	7.0e-20	89.7	COG1765	Uncharacterized OsmC-related protein	137
649977454	227	45.22	1	157	3	154	1.0e-36	146	COG1321	Mn-dependent transcriptional regulator, DtxR family	154
649977456	89	49.12	33	89	5	61	9.0e-11	58.7	COG0199	Ribosomal protein S14	61
649977461	343	26.79	56	329	36	297	2.0e-13	70.7	COG3547	Transposase	303
649977462	381	42.19	3	362	2	366	8.0e-110	390	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
649977463	291	32.24	35	278	9	246	6.0e-37	148	COG1427	Predicted periplasmic solute-binding protein	252
649977465	438	43.16	5	323	2	330	2.0e-92	332	COG0460	Homoserine dehydrogenase	333
649977466	542	30.52	30	512	1	473	6.0e-70	258	COG3119	Arylsulfatase A or related enzyme	475
649977469	150	25	24	150	1	126	6.0e-10	56.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
649977471	328	38.1	3	315	9	314	5.0e-75	274	COG0837	Glucokinase	320
649977472	474	52.75	2	473	1	462	0.0e+00	627	COG0114	Fumarate hydratase class II	462
649977474	142	29.71	1	137	2	130	1.0e-16	78.7	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
649977478	346	50	21	216	5	202	1.0e-50	193	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
649977480	370	43.58	1	367	2	355	2.0e-108	386	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
649977482	956	20.98	467	762	35	330	1.0e-03	39.5	COG1413	HEAT repeat	335
649977483	543	40.11	158	536	33	406	3.0e-92	333	COG1301	Na+/H+-dicarboxylate symporter	415
649977484	67	54.39	1	57	1	57	2.0e-12	64.2	COG1551	sRNA-binding carbon storage regulator CsrA	73
649977485	347	28.13	1	347	4	340	8.0e-35	141	COG0673	Predicted dehydrogenase	342
649977486	294	24.18	37	284	18	278	2.0e-15	76.6	COG1234	Ribonuclease BN, tRNA processing enzyme	292
649977488	585	24.22	26	278	12	267	2.0e-08	54.2	COG0457	Tetratricopeptide (TPR) repeat	291
649977490	156	29.5	19	155	11	130	1.0e-10	59.5	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
649977491	453	52.15	12	426	7	420	0.0e+00	518	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
649977493	301	27.31	49	279	12	251	2.0e-23	102	COG1082	Sugar phosphate isomerase/epimerase	274
649977495	619	49.76	1	619	1	597	0.0e+00	773	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
649977499	304	44.24	35	303	1	264	6.0e-67	247	COG0548	Acetylglutamate kinase	265
649977500	400	46.68	3	389	1	392	0.0e+00	480	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
649977501	306	50.82	1	302	6	309	5.0e-108	384	COG0078	Ornithine carbamoyltransferase	310
649977502	524	56.46	5	524	3	515	0.0e+00	710	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
649977507	343	26.79	56	329	36	297	2.0e-13	70.7	COG3547	Transposase	303
649977511	155	39.57	9	146	2	140	9.0e-32	129	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
649977512	721	50.07	14	692	17	693	0.0e+00	734	COG1298	Flagellar biosynthesis pathway, component FlhA	696
649977513	437	27.84	3	430	2	394	8.0e-66	244	COG1419	Flagellar biosynthesis GTPase FlhF	407
649977514	302	31.89	38	285	3	248	3.0e-36	145	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
649977515	259	34.24	3	254	1	247	4.0e-44	171	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
649977524	378	32.95	31	376	10	320	1.0e-37	151	COG0530	Ca2+/Na+ antiporter	320
649977527	1043	20.38	1	1020	1	973	9.0e-58	219	COG4717	Uncharacterized protein YhaN	984
649977531	261	33.86	7	248	4	250	6.0e-33	134	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649977532	242	44.07	8	235	10	232	1.0e-56	212	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
649977534	137	37.07	1	116	1	116	2.0e-25	108	COG3795	Uncharacterized conserved protein	123
649977535	254	52.12	6	239	3	238	8.0e-86	310	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
649977536	322	32.8	13	322	4	302	6.0e-54	204	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
649977537	659	29.97	114	475	126	492	1.0e-44	175	COG0464	AAA+-type ATPase, SpoVK/Ycf46/Vps4 family	494
649977540	425	26.17	12	361	17	375	2.0e-19	90.6	COG0531	Amino acid transporter	466
649977541	248	25.87	75	246	40	238	5.0e-16	78.4	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
649977542	932	49	335	931	2	592	0.0e+00	635	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
649977545	261	35.8	1	243	1	237	2.0e-53	202	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
649977546	482	25	36	377	4	315	1.0e-26	114	COG0673	Predicted dehydrogenase	342
649977547	258	44.36	1	254	4	260	5.0e-72	264	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
649977549	272	43.65	19	267	2	246	4.0e-65	241	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
649977550	411	36.74	1	405	4	410	3.0e-74	272	COG2195	Di- or tripeptidase	414
649977551	401	37.68	1	395	4	399	9.0e-85	307	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archeal type	408
649977555	518	19.04	71	441	46	444	6.0e-18	85.8	COG3540	Phosphodiesterase/alkaline phosphatase D	522
649977557	362	42.11	21	342	2	323	6.0e-75	274	COG0042	tRNA-dihydrouridine synthase	323
649977558	424	28.82	78	363	59	344	1.0e-35	144	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
649977560	1066	28.72	5	1018	1	951	0.0e+00	475	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
649977561	621	19.49	26	399	17	391	2.0e-18	87.8	COG0732	Restriction endonuclease S subunit	391
649977562	524	29.87	2	513	1	482	4.0e-76	279	COG0286	Type I restriction-modification system, DNA methylase subunit	489
649977571	260	27.2	6	126	2	123	1.0e-14	74	COG3293	Transposase	124
649977583	107	36.79	2	107	3	107	3.0e-16	76.9	COG5614	Bacteriophage head-tail adaptor	109
649977586	399	20.72	9	391	20	414	1.0e-23	104	COG4653	Predicted phage phi-C31 gp36 major capsid-like protein	422
649977587	192	37.13	12	169	12	176	3.0e-21	95.1	COG3740	Phage head maturation protease	194
649977588	507	27.43	33	376	43	388	8.0e-46	178	COG4695	Phage portal protein BeeE	398
649977590	515	26.02	2	500	35	534	7.0e-77	281	COG4626	Phage terminase-like protein, large subunit, contains N-terminal HTH domain	546
649977591	160	29.5	4	139	2	138	1.0e-13	69.7	COG3747	Phage terminase, small subunit	160
649977598	302	30.1	7	301	6	296	7.0e-48	184	COG3781	Predicted membrane chloride channel, bestrophin family	306
649977599	223	42.31	1	205	4	207	3.0e-43	168	COG0288	Carbonic anhydrase	207
649977603	751	28.53	120	425	2	331	2.0e-38	154	COG0515	Serine/threonine protein kinase	384
649977607	278	36.36	39	277	29	276	9.0e-47	180	COG3258	Cytochrome c	293
649977608	182	21.56	15	181	16	169	2.0e-10	59.2	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
649977609	197	25.38	1	197	3	199	1.0e-09	56.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649977610	322	25.96	40	318	3	281	5.0e-23	102	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649977611	163	69.18	14	159	5	149	2.0e-52	198	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
649977613	453	29.9	19	438	1	459	5.0e-64	238	COG3119	Arylsulfatase A or related enzyme	475
649977614	421	18.52	65	421	8	380	4.0e-16	79.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649977616	264	27.99	3	259	1	261	1.0e-31	130	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
649977621	347	22.82	61	347	35	308	2.0e-25	110	COG0657	Acetyl esterase/lipase	312
649977623	1172	45.53	9	1120	1	1110	0.0e+00	1174	COG0587	DNA polymerase III, alpha subunit	1139
649977625	57	36.84	1	57	1	54	5.0e-05	39.5	COG3847	Flp pilus assembly protein, pilin Flp	58
649977628	418	29.49	1	221	1	233	6.0e-21	95.4	COG3745	Flp pilus assembly protein CpaB	276
649977629	714	33.57	66	480	29	433	4.0e-64	240	COG4964	Flp pilus assembly protein, secretin CpaC	455
649977631	439	19.89	75	417	1	349	1.0e-17	84.5	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649977632	210	20.5	32	173	3	150	2.0e-08	52.5	COG1225	Peroxiredoxin	157
649977638	308	29.9	13	303	3	296	3.0e-40	159	COG1597	Diacylglycerol kinase family enzyme	301
649977639	429	24.62	90	421	8	239	1.0e-20	94.6	COG0176	Transaldolase	239
649977643	579	17.23	18	459	3	414	3.0e-13	70.5	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
649977646	162	62.07	12	155	8	152	1.0e-49	189	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
649977648	316	23.81	24	310	16	292	5.0e-29	121	COG2040	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)	300
649977649	316	25.84	19	310	11	292	2.0e-36	146	COG2040	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)	300
649977651	475	37.81	1	470	28	508	2.0e-114	406	COG0513	Superfamily II DNA and RNA helicase	513
649977652	496	31.97	33	451	1	443	4.0e-54	206	COG3119	Arylsulfatase A or related enzyme	475
649977653	127	33.33	6	107	1	99	3.0e-07	47.6	COG2105	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family	120
649977654	392	27.59	10	283	1	273	2.0e-28	120	COG3320	Thioester reductase domain of alpha aminoadipate reductase Lys2 and NRPSs	382
649977656	451	60.75	1	451	1	447	0.0e+00	615	COG1726	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA	447
649977657	419	54.99	4	412	2	400	1.0e-109	390	COG1805	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB	400
649977658	276	42.11	2	266	5	259	1.0e-63	236	COG2869	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC	264
649977659	208	65.05	2	207	3	208	5.0e-73	267	COG1347	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD	208
649977660	206	72.82	1	206	1	198	3.0e-73	268	COG2209	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE	198
649977661	406	69.61	1	406	4	410	0.0e+00	638	COG2871	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF	410
649977662	349	41.84	8	341	3	332	3.0e-86	312	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
649977664	399	37.84	6	397	5	403	3.0e-96	345	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
649977665	110	41.18	1	84	5	89	4.0e-08	49.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
649977668	372	24.58	9	366	3	347	2.0e-35	143	COG0628	Predicted PurR-regulated permease PerM	355
649977669	163	17.65	1	141	2	141	4.0e-03	34.9	COG1247	L-amino acid N-acyltransferase YncA	169
649977670	426	27.86	7	394	7	405	2.0e-33	137	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
649977671	489	41.47	24	483	11	481	3.0e-124	439	COG0260	Leucyl aminopeptidase	485
649977677	315	33.67	4	281	1	292	5.0e-68	251	COG1131	ABC-type multidrug transport system, ATPase component	293
649977681	338	28.66	7	334	8	331	2.0e-47	183	COG0618	nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs	332
649977684	310	21.43	162	309	8	152	1.0e-03	37.6	COG4978	Bacterial effector-binding domain	153
649977685	751	58.39	56	751	29	724	0.0e+00	963	COG3968	Glutamine synthetase type III	724
649977686	338	38.89	1	335	5	342	5.0e-63	235	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
649977687	488	45.81	1	463	2	452	1.0e-130	460	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
649977690	344	26.61	21	265	5	245	3.0e-22	99.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649977692	246	21.4	1	243	3	273	4.0e-10	58.7	COG1082	Sugar phosphate isomerase/epimerase	274
649977694	260	27.2	6	126	2	123	1.0e-14	74	COG3293	Transposase	124
649977695	409	25.12	8	407	6	422	1.0e-29	124	COG1029	Formylmethanofuran dehydrogenase subunit B	429
649977696	510	41.36	8	493	4	467	5.0e-124	438	COG2870	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase	467
649977697	350	30.7	1	339	2	329	3.0e-45	176	COG0859	ADP-heptose:LPS heptosyltransferase	334
649977698	480	27.19	20	419	1	442	7.0e-44	172	COG3119	Arylsulfatase A or related enzyme	475
649977701	415	16.98	29	412	2	376	7.0e-06	45.3	COG2327	Polysaccharide pyruvyl transferase family protein WcaK	385
649977705	282	30.86	31	271	18	258	2.0e-31	129	COG2912	Regulator of sirC expression, contains transglutaminase-like and TPR domains	269
649977706	385	25.9	64	381	26	339	2.0e-31	130	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649977707	180	52.57	1	175	1	173	2.0e-57	215	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
649977710	214	36.84	13	200	6	192	2.0e-36	146	COG0406	Broad specificity phosphatase PhoE	208
649977711	195	35.71	1	192	2	185	9.0e-31	126	COG0742	16S rRNA G966 N2-methylase RsmD	187
649977712	520	32.35	26	483	4	473	1.0e-67	251	COG3119	Arylsulfatase A or related enzyme	475
649977715	445	19.64	47	359	2	296	1.0e-09	57.9	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649977718	461	29.77	22	457	2	467	9.0e-63	234	COG3119	Arylsulfatase A or related enzyme	475
649977719	272	22.32	50	267	4	226	8.0e-18	84.6	COG1011	FMN phosphatase YigB, HAD superfamily	229
649977720	406	45	17	395	9	371	5.0e-113	401	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649977721	418	46.35	2	188	34	225	1.0e-63	237	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
649977722	417	24.33	1	405	1	379	2.0e-23	103	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649977723	366	36.76	1	359	3	370	6.0e-96	344	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
649977724	396	20.88	1	371	1	381	2.0e-27	117	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649977726	457	24.31	35	455	14	437	3.0e-47	183	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
649977727	502	21.54	36	485	14	463	3.0e-12	67	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
649977730	381	46.58	2	372	1	372	8.0e-116	410	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649977731	406	28.07	72	403	2	338	3.0e-50	192	COG0673	Predicted dehydrogenase	342
649977733	467	46.61	1	467	4	457	0.0e+00	477	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649977734	505	27.46	180	504	10	334	3.0e-29	123	COG0642	Signal transduction histidine kinase	336
649977735	344	25.62	3	158	2	149	4.0e-09	55.8	COG2165	Type II secretory pathway, pseudopilin PulG	149
649977740	497	62.83	3	497	5	499	0.0e+00	768	COG0554	Glycerol kinase	499
649977741	594	41.21	41	590	26	588	0.0e+00	518	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
649977742	301	30.65	7	125	6	127	1.0e-09	57.4	COG2165	Type II secretory pathway, pseudopilin PulG	149
649977743	300	28.46	7	124	6	128	1.0e-09	57.4	COG2165	Type II secretory pathway, pseudopilin PulG	149
649977744	409	25.79	1	401	1	379	5.0e-26	112	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649977746	183	46.95	9	170	9	169	4.0e-45	174	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
649977748	171	25	22	145	6	123	2.0e-05	42.7	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
649977750	166	48.12	7	166	5	159	3.0e-51	194	COG0669	Phosphopantetheine adenylyltransferase	159
649977751	797	34.63	314	620	34	327	4.0e-45	176	COG0642	Signal transduction histidine kinase	336
649977752	614	36.7	171	614	54	499	1.0e-128	454	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649977755	304	38.37	7	263	3	256	1.0e-43	170	COG1774	Cell fate regulator YaaT, PSP1 superfamily (controls sporulation, competence, biofilm development)	265
649977757	292	25.36	1	288	6	346	9.0e-31	127	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
649977759	244	32.93	10	244	9	255	1.0e-43	169	COG0300	Short-chain dehydrogenase	265
649977761	694	49.21	4	692	6	687	0.0e+00	728	COG0480	Translation elongation factor EF-G, a GTPase	697
649977768	461	20.25	82	461	45	439	1.0e-12	68.5	COG3659	Carbohydrate-selective porin OprB	439
649977769	334	23.11	60	264	6	175	4.0e-05	42.6	COG0560	Phosphoserine phosphatase	212
649977770	526	30.64	26	467	1	459	8.0e-76	278	COG3119	Arylsulfatase A or related enzyme	475
649977772	318	20.67	1	150	7	153	2.0e-05	44	COG4875	Uncharacterized protein	156
649977774	544	26.45	126	491	104	459	3.0e-12	66.9	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
649977776	158	32.24	8	157	6	155	4.0e-13	67.7	COG4539	Uncharacterized membrane protein YGL010W	180
649977781	487	27.91	23	461	1	470	1.0e-51	198	COG3119	Arylsulfatase A or related enzyme	475
649977785	584	28.45	19	410	1	452	5.0e-61	229	COG3119	Arylsulfatase A or related enzyme	475
649977787	186	43.17	3	185	27	206	3.0e-43	168	COG1859	RNA:NAD 2'-phosphotransferase, TPT1/KptA family	211
649977788	478	56.46	1	478	2	478	0.0e+00	627	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
649977789	326	37.07	1	317	1	313	5.0e-69	254	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
649977790	323	25	10	323	15	318	2.0e-31	130	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
649977791	851	35.06	19	499	7	488	4.0e-115	409	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
649977792	294	27.52	1	292	11	307	5.0e-36	144	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
649977798	315	23.01	1	239	2	214	5.0e-25	108	COG1192	Cellulose biosynthesis protein BcsQ	259
649977799	132	33.96	29	132	7	108	6.0e-11	59.9	COG0607	Rhodanese-related sulfurtransferase	110
649977806	363	57.57	1	363	3	372	0.0e+00	467	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
649977808	258	42.52	3	253	6	259	5.0e-68	251	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
649977809	374	37.87	6	360	9	369	2.0e-61	230	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
649977810	492	29.62	30	456	3	442	3.0e-52	199	COG3119	Arylsulfatase A or related enzyme	475
649977811	469	28.1	20	450	1	443	4.0e-44	172	COG3119	Arylsulfatase A or related enzyme	475
649977812	527	24.24	27	417	1	452	2.0e-36	147	COG3119	Arylsulfatase A or related enzyme	475
649977813	899	27.54	132	424	2	277	3.0e-31	131	COG0515	Serine/threonine protein kinase	384
649977819	479	33.33	42	479	1	438	9.0e-73	267	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
649977833	190	23.08	9	164	5	136	5.0e-08	51.4	COG1943	REP element-mobilizing transposase RayT	136
649977835	553	25.72	270	544	6	307	2.0e-24	107	COG0657	Acetyl esterase/lipase	312
649977837	260	27.2	6	126	2	123	8.0e-15	74.4	COG3293	Transposase	124
649977838	280	25.22	51	255	69	290	6.0e-17	81.5	COG0657	Acetyl esterase/lipase	312
649977840	401	22.07	39	394	4	344	5.0e-20	92.5	COG3515	Predicted component of the type VI protein secretion system	346
649977841	172	48.81	1	168	1	168	5.0e-52	197	COG3516	Predicted component of the type VI protein secretion system	169
649977842	499	54.33	5	497	3	492	0.0e+00	680	COG3517	Predicted component of the type VI protein secretion system	495
649977843	537	39.88	17	535	2	494	0.0e+00	485	COG3517	Predicted component of the type VI protein secretion system	495
649977844	266	37.35	5	260	10	264	2.0e-42	165	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion	273
649977845	157	39.61	1	154	1	153	2.0e-22	98.9	COG3518	Predicted component of the type VI protein secretion system	157
649977846	613	37.52	1	613	1	621	8.0e-128	451	COG3519	Type VI protein secretion system component VasA	621
649977847	366	29.8	14	362	24	333	8.0e-58	217	COG3520	Predicted component of the type VI protein secretion system	335
649977848	884	40.32	12	877	1	778	0.0e+00	766	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
649977849	165	35.1	1	145	1	149	7.0e-27	113	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
649977851	199	27.15	1	146	1	142	7.0e-17	80.7	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
649977853	191	27.27	32	145	27	147	8.0e-14	70.3	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
649977854	174	25.57	1	174	1	162	6.0e-22	96.9	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
649977855	654	37.34	5	558	6	550	0.0e+00	480	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
649977856	96	39.39	1	96	1	98	2.0e-08	51.1	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
649977859	478	26.32	8	437	9	428	5.0e-44	172	COG3522	Predicted component of the type VI protein secretion system	446
649977860	213	23.76	14	208	48	238	2.0e-12	65.7	COG3455	Type VI protein secretion system component VasF	262
649977863	66	40	1	65	3	67	4.0e-07	46.4	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
649977864	297	41.27	47	292	1	249	1.0e-54	206	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649977867	63	48.21	9	63	1	56	5.0e-11	59.3	COG0401	Uncharacterized membrane protein YqaE, homolog of Blt101, UPF0057 family	56
649977869	491	37.5	66	487	3	436	2.0e-108	386	COG0621	tRNA A37 methylthiotransferase MiaB	437
649977871	228	28.7	1	222	2	204	2.0e-29	122	COG0125	Thymidylate kinase	208
649977872	159	42.31	1	150	4	157	3.0e-40	158	COG1225	Peroxiredoxin	157
649977873	315	23.9	141	298	23	175	3.0e-09	56.3	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649977874	601	18.98	131	597	72	458	4.0e-27	116	COG0471	Di- and tricarboxylate transporter	461
649977875	331	25.23	1	328	1	272	1.0e-47	183	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
649977876	253	25.33	33	253	5	223	1.0e-15	77.1	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649977877	121	28.7	1	108	8	115	2.0e-07	47.9	COG2456	Uncharacterized protein	121
649977879	495	31.72	114	475	4	345	1.0e-58	221	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
649977880	376	22.65	27	375	2	349	4.0e-12	66	COG1363	Putative aminopeptidase FrvX	355
649977882	403	25.19	23	398	14	396	2.0e-29	123	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
649977885	266	24.81	7	261	3	266	5.0e-29	121	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
649977886	186	46.63	8	181	3	179	3.0e-42	165	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
649977887	339	62.02	2	337	1	331	0.0e+00	464	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
649977888	172	38.05	49	160	3	113	3.0e-19	88	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
649977889	364	46.02	6	357	2	348	4.0e-85	308	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
649977890	285	37.74	5	268	3	263	4.0e-65	241	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
649977892	94	45.45	1	94	27	124	1.0e-27	114	COG2343	Uncharacterized conserved protein, DUF427 family	132
649977893	385	42.27	18	373	19	379	4.0e-68	252	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
649977894	194	30.49	1	163	11	157	4.0e-19	88	COG0597	Lipoprotein signal peptidase	167
649977896	1074	16.9	323	670	89	407	2.0e-06	49.4	COG3307	O-antigen ligase	424
649977897	771	32.05	508	736	21	249	6.0e-43	169	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
649977903	283	22.76	6	261	5	258	3.0e-22	99.1	COG1082	Sugar phosphate isomerase/epimerase	274
649977904	537	28.11	14	530	4	457	2.0e-46	180	COG0471	Di- and tricarboxylate transporter	461
649977906	281	24.64	1	279	5	257	3.0e-07	49.6	COG0730	Uncharacterized membrane protein YfcA	258
649977907	241	28.92	13	176	7	166	8.0e-12	64.1	COG0321	Lipoate-protein ligase B	221
649977908	306	55.78	11	302	12	305	1.0e-114	406	COG0320	Lipoate synthase	306
649977910	381	44.93	9	372	1	363	4.0e-119	421	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
649977911	171	66.04	4	162	1	157	6.0e-61	226	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
649977912	609	31.56	182	557	18	336	7.0e-46	178	COG0642	Signal transduction histidine kinase	336
649977920	405	24.56	58	395	18	348	1.0e-39	157	COG0628	Predicted PurR-regulated permease PerM	355
649977923	358	23.95	6	308	1	278	2.0e-21	96.9	COG0492	Thioredoxin reductase	305
649977924	89	32	5	79	1	75	8.0e-06	42	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
649977927	215	32.16	14	183	18	176	5.0e-32	131	COG0279	Phosphoheptose isomerase	176
649977928	1112	20	67	361	108	398	9.0e-11	63.5	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
649977930	474	50.35	189	470	1	262	9.0e-85	307	COG1760	L-serine deaminase	262
649977932	325	38.78	53	314	58	310	4.0e-58	218	COG0657	Acetyl esterase/lipase	312
649977933	152	46.9	34	146	10	122	1.0e-29	122	COG0818	Diacylglycerol kinase	123
649977934	528	53.08	21	522	4	483	0.0e+00	625	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
649977935	475	25.55	30	456	3	471	5.0e-40	159	COG3119	Arylsulfatase A or related enzyme	475
649977941	225	19.39	4	222	19	281	5.0e-08	51.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649977943	361	36.59	1	344	1	354	3.0e-70	259	COG4956	Uncharacterized conserved protein YacL, contains PIN and TRAM domains	356
649977947	529	35.77	37	291	1	260	2.0e-39	157	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
649977948	238	25.59	1	210	5	195	4.0e-16	78.8	COG0684	Regulator of RNase E activity RraA	210
649977949	199	21.3	2	197	1	216	3.0e-16	78.5	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
649977950	487	24.55	44	351	7	314	1.0e-30	127	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
649977951	176	26.09	26	161	6	143	1.0e-16	79.7	COG0071	Molecular chaperone IbpA, HSP20 family	146
649977952	176	33.33	61	176	30	146	3.0e-14	71.6	COG0071	Molecular chaperone IbpA, HSP20 family	146
649977953	146	38.89	18	143	20	143	3.0e-22	97.8	COG0071	Molecular chaperone IbpA, HSP20 family	146
649977954	493	20.41	352	474	16	156	3.0e-03	37.1	COG5126	Ca2+-binding protein, EF-hand superfamily	160
649977955	208	18.04	18	194	8	197	7.0e-06	44.1	COG0740	ATP-dependent protease ClpP, protease subunit	200
649977959	110	50.93	1	108	3	108	4.0e-31	126	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
649977960	464	45.62	26	464	1	436	4.0e-117	415	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
649977963	154	26.17	29	134	11	105	1.0e-09	56.2	COG0727	Fe-S-cluster containining protein	132
649977964	189	48.37	1	183	1	181	2.0e-53	202	COG2096	Cob(I)alamin adenosyltransferase	184
649977965	302	25.09	8	270	16	286	2.0e-24	106	COG0657	Acetyl esterase/lipase	312
649977967	405	18.13	178	355	9	201	3.0e-04	39.9	COG2755	Lysophospholipase L1 or related esterase	216
649977968	225	25.48	15	213	1	206	2.0e-17	82.7	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
649977976	128	40.48	2	127	5	127	2.0e-31	128	COG2346	Truncated hemoglobin YjbI	133
649977977	486	43.88	8	486	7	488	0.0e+00	530	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
649977983	327	21.59	55	324	8	306	1.0e-09	57.7	COG3021	Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily	309
649977986	258	34.9	1	253	2	252	8.0e-38	150	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
649977987	228	35.71	14	223	66	285	2.0e-38	152	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
649977992	110	60.71	2	110	1	112	5.0e-38	149	COG2824	Uncharacterized Zn-ribbon-containing protein	112
649977994	302	36.86	2	288	4	279	2.0e-56	212	COG1686	D-alanyl-D-alanine carboxypeptidase	389
649977998	323	26	8	156	3	149	2.0e-10	60.4	COG2165	Type II secretory pathway, pseudopilin PulG	149
649977999	383	24.64	1	271	55	329	6.0e-36	145	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
649978003	334	24.49	6	148	5	147	2.0e-09	57	COG2165	Type II secretory pathway, pseudopilin PulG	149
649978006	472	49.23	16	470	6	456	0.0e+00	497	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649978007	275	41.67	9	271	4	262	1.0e-74	272	COG0159	Tryptophan synthase alpha chain	265
649978008	409	68.19	17	409	3	394	0.0e+00	671	COG0133	Tryptophan synthase beta chain	396
649978010	469	21.38	16	458	2	414	4.0e-44	172	COG1239	Mg-chelatase subunit ChlI	423
649978012	366	24.93	1	363	1	349	2.0e-30	126	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
649978014	181	34.36	12	173	7	166	3.0e-32	131	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
649978016	134	20.83	19	114	8	100	6.0e-05	40	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
649978021	387	50.59	57	224	6	174	1.0e-62	233	COG0225	Peptide methionine sulfoxide reductase MsrA	174
649978023	292	36.21	6	291	3	289	2.0e-60	226	COG0040	ATP phosphoribosyltransferase	290
649978024	503	25.06	97	503	49	426	2.0e-21	97.8	COG3746	Phosphate-selective porin	426
649978026	363	30.66	14	350	3	349	5.0e-49	188	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
649978031	455	30.98	29	437	2	446	3.0e-60	226	COG3119	Arylsulfatase A or related enzyme	475
649978032	314	29.97	2	304	1	296	1.0e-49	190	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
649978037	465	20.21	156	331	48	230	1.0e-04	41.5	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
649978039	1255	26.57	306	1225	1	833	2.0e-103	371	COG3264	Small-conductance mechanosensitive channel	835
649978041	532	53.28	12	529	17	529	0.0e+00	664	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
649978042	485	23.61	105	479	16	371	5.0e-26	112	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
649978045	95	26.97	1	88	1	88	8.0e-11	58.4	COG1359	Quinol monooxygenase YgiN	100
649978046	271	29.37	6	269	3	247	1.0e-34	140	COG1521	Pantothenate kinase type III	251
649978050	313	48.42	1	312	31	340	2.0e-90	326	COG0552	Signal recognition particle GTPase	340
649978052	666	32.78	17	666	5	639	2.0e-108	386	COG1199	Rad3-related DNA helicase	654
649978053	1086	28.73	364	715	4	335	1.0e-24	109	COG1413	HEAT repeat	335
649978054	252	15.27	9	137	3	124	2.0e-09	56.3	COG3293	Transposase	124
649978056	131	30.71	3	128	1	120	5.0e-13	66.7	COG3293	Transposase	124
649978061	252	15.27	9	137	3	124	2.0e-10	59.7	COG3293	Transposase	124
649978063	408	29.29	1	408	15	434	2.0e-73	269	COG0612	Predicted Zn-dependent peptidase	438
649978064	420	27.49	10	406	21	431	8.0e-58	218	COG0612	Predicted Zn-dependent peptidase	438
649978066	322	40.95	10	319	5	309	9.0e-72	263	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
649978067	811	32.86	18	286	2	279	8.0e-37	149	COG0515	Serine/threonine protein kinase	384
649978068	890	60.68	5	889	1	861	0.0e+00	1217	COG1048	Aconitase A	861
649978071	227	25	24	197	29	202	2.0e-12	66.5	COG3897	Predicted nicotinamide N-methyase	218
649978073	336	44.52	13	320	1	289	6.0e-75	274	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
649978074	901	22.1	247	605	117	453	8.0e-17	83.3	COG1538	Outer membrane protein TolC	457
649978075	332	35.06	9	332	3	323	9.0e-59	220	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
649978076	352	27.89	2	351	1	342	4.0e-37	149	COG0673	Predicted dehydrogenase	342
649978077	255	17.79	80	240	27	170	8.0e-10	57.7	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
649978078	296	34.06	4	275	2	275	3.0e-56	212	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
649978079	354	28.05	9	338	3	334	2.0e-35	143	COG0673	Predicted dehydrogenase	342
649978080	162	51.92	1	156	1	156	2.0e-42	164	COG2193	Bacterioferritin (cytochrome b1)	157
649978081	591	38.1	4	487	3	524	2.0e-121	429	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
649978082	149	27.81	1	148	1	143	2.0e-12	65.7	COG4154	L-fucose mutarotase/ribose pyranase, RbsD/FucU family	144
649978084	284	22.7	6	282	4	305	3.0e-21	96.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649978085	374	17.87	2	368	1	357	3.0e-13	69.6	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
649978087	267	25.45	20	229	27	235	6.0e-15	75	COG3907	Membrane-associated enzyme, PAP2 (acid phosphatase) superfamily	249
649978088	155	37.5	39	150	13	123	3.0e-08	51.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
649978089	232	36.48	1	232	1	243	4.0e-48	184	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
649978090	158	31.3	18	148	9	135	3.0e-13	68.1	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
649978091	457	45.77	30	452	32	459	6.0e-129	454	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
649978093	353	30.79	34	335	5	281	2.0e-34	140	COG3481	3'-5' exoribonuclease YhaM, can participate in 23S rRNA maturation,  HD superfamily	287
649978094	241	29.72	20	240	14	237	2.0e-26	113	COG0095	Lipoate-protein ligase A	248
649978095	505	49.16	9	478	8	475	0.0e+00	557	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
649978096	447	42.66	9	445	17	444	2.0e-129	455	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
649978097	128	45.6	4	126	7	131	2.0e-32	131	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
649978098	152	49.66	1	145	1	147	3.0e-44	171	COG0698	Ribose 5-phosphate isomerase RpiB	151
649978099	394	32.24	240	391	3	139	6.0e-27	115	COG0394	Protein-tyrosine-phosphatase	139
649978102	331	27.35	10	223	3	216	5.0e-10	58.9	COG1994	Zn-dependent protease (includes SpoIVFB)	230
649978104	410	30.68	9	410	4	390	7.0e-71	261	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
649978105	1454	45.34	16	844	6	808	0.0e+00	792	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
649978106	1238	44.99	18	871	16	808	0.0e+00	748	COG0085	DNA-directed RNA polymerase, beta subunit/140 kD subunit	1060
649978107	138	52.38	13	138	4	124	3.0e-21	94.5	COG0222	Ribosomal protein L7/L12	124
649978108	171	31.21	1	171	3	175	3.0e-21	94.9	COG0244	Ribosomal protein L10	175
649978109	234	53.22	1	232	1	225	1.0e-72	266	COG0081	Ribosomal protein L1	228
649978110	141	57.86	2	141	1	140	5.0e-50	189	COG0080	Ribosomal protein L11	141
649978111	199	44.63	24	199	2	177	1.0e-41	162	COG0250	Transcription antitermination factor NusG	178
649978114	51	52	1	49	1	50	6.0e-07	46	COG0267	Ribosomal protein L33	50
649978115	398	71.11	1	398	1	394	0.0e+00	618	COG0050	Translation elongation factor EF-Tu, a GTPase	394
649978121	460	22.12	63	360	19	332	2.0e-20	94.1	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649978122	191	34.39	27	183	20	171	5.0e-22	97.6	COG3153	Predicted N-acetyltransferase YhbS	171
649978124	395	18.06	26	395	23	366	8.0e-26	111	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
649978129	217	43.75	14	216	1	200	1.0e-55	210	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
649978130	165	28.68	20	155	5	140	6.0e-20	90.3	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
649978131	256	32.1	4	242	47	310	8.0e-42	164	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649978132	261	45.28	7	258	19	272	4.0e-60	225	COG3752	Steroid 5-alpha reductase family enzyme	272
649978133	350	26.43	68	343	18	282	1.0e-56	213	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
649978134	419	45.14	129	416	1	283	4.0e-87	315	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
649978135	276	36.65	26	276	4	247	5.0e-57	214	COG3496	Uncharacterized conserved protein, DUF1365 family	261
649978136	431	43.24	1	411	9	420	2.0e-125	442	COG2907	Predicted NAD/FAD-binding protein	447
649978137	519	45.12	1	512	2	499	0.0e+00	529	COG3046	Uncharacterized protein related to deoxyribodipyrimidine photolyase	505
649978139	440	32.9	50	431	34	411	1.0e-69	257	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
649978140	387	22.53	14	340	7	359	2.0e-24	106	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649978141	436	42.02	59	434	4	377	1.0e-94	340	COG1454	Alcohol dehydrogenase, class IV	377
649978148	129	33.33	1	128	2	129	2.0e-20	91.1	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
649978150	1077	25.26	74	348	58	327	1.0e-11	65.8	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
649978152	428	43.68	1	428	1	429	0.0e+00	470	COG0172	Seryl-tRNA synthetase	429
649978153	384	40.31	4	383	23	404	2.0e-80	292	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
649978154	155	51.68	10	155	4	147	9.0e-43	165	COG0328	Ribonuclease HI	154
649978155	72	66.67	1	72	1	72	1.0e-23	101	COG0361	Translation initiation factor IF-1	75
649978156	267	22.09	22	263	19	251	7.0e-24	104	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
649978159	724	26.86	94	722	86	761	7.0e-84	305	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
649978161	107	66.34	5	105	2	102	9.0e-35	138	COG0051	Ribosomal protein S10	104
649978162	231	47.37	4	229	3	211	4.0e-63	234	COG0087	Ribosomal protein L3	218
649978163	217	37.74	1	209	1	212	8.0e-43	166	COG0088	Ribosomal protein L4	214
649978164	102	43.96	13	102	1	91	1.0e-19	87.9	COG0089	Ribosomal protein L23	94
649978165	284	58.33	1	276	1	274	1.0e-96	346	COG0090	Ribosomal protein L2	275
649978166	89	65.17	1	89	1	89	1.0e-32	131	COG0185	Ribosomal protein S19	93
649978167	114	41.9	4	108	11	115	1.0e-23	101	COG0091	Ribosomal protein L22	120
649978168	233	46.05	12	233	1	228	9.0e-58	216	COG0092	Ribosomal protein S3	233
649978169	140	52.9	1	136	1	138	2.0e-38	151	COG0197	Ribosomal protein L16/L10AE	146
649978170	77	47.54	1	61	2	62	4.0e-07	46.4	COG0255	Ribosomal protein L29	69
649978171	105	56.25	1	80	7	86	9.0e-21	91.8	COG0186	Ribosomal protein S17	87
649978172	122	64.75	1	122	1	122	8.0e-43	165	COG0093	Ribosomal protein L14	122
649978173	119	40.57	1	105	3	104	1.0e-14	71.9	COG0198	Ribosomal protein L24	104
649978174	184	60.34	1	179	1	179	7.0e-66	243	COG0094	Ribosomal protein L5	180
649978175	131	56.49	1	131	2	132	2.0e-44	171	COG0096	Ribosomal protein S8	132
649978176	181	54.49	1	178	1	176	2.0e-54	204	COG0097	Ribosomal protein L6P/L9E	178
649978177	121	52.42	1	121	2	125	9.0e-29	118	COG0256	Ribosomal protein L18	125
649978178	159	58.28	10	159	25	175	3.0e-47	181	COG0098	Ribosomal protein S5	181
649978179	150	46.76	13	148	13	151	7.0e-29	119	COG0200	Ribosomal protein L15	152
649978180	455	41.81	1	450	6	431	4.0e-100	358	COG0201	Preprotein translocase subunit SecY	436
649978181	262	45.53	1	254	2	252	1.0e-72	266	COG0024	Methionine aminopeptidase	255
649978183	38	81.58	1	38	1	38	2.0e-06	44.4	COG0257	Ribosomal protein L36	38
649978184	128	54.55	1	121	1	121	3.0e-35	140	COG0099	Ribosomal protein S13	121
649978185	126	60.32	1	126	4	129	4.0e-40	156	COG0100	Ribosomal protein S11	129
649978186	338	44.13	15	329	6	307	2.0e-81	296	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
649978187	230	42.35	1	170	1	116	9.0e-31	127	COG0203	Ribosomal protein L17	116
649978188	509	53.44	5	251	2	244	2.0e-78	286	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
649978190	484	32.18	24	455	1	446	1.0e-62	234	COG3119	Arylsulfatase A or related enzyme	475
649978192	273	24.19	3	268	1	274	4.0e-25	108	COG1082	Sugar phosphate isomerase/epimerase	274
649978197	469	29.81	21	449	1	448	2.0e-54	206	COG3119	Arylsulfatase A or related enzyme	475
649978198	157	31.65	5	152	7	157	3.0e-18	84.6	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
649978200	173	30.63	11	170	2	161	3.0e-23	101	COG2323	Uncharacterized membrane protein YcaP, DUF421 family	224
649978201	660	32.14	534	645	18	127	7.0e-09	56.1	COG0526	Thiol-disulfide isomerase or thioredoxin	127
649978203	269	34.15	103	262	9	168	5.0e-21	95	COG1386	Chromosome segregation and condensation protein ScpB	184
649978204	312	23.55	11	267	6	208	1.0e-14	74.2	COG1018	Ferredoxin-NADP reductase	266
649978205	329	47.37	7	328	3	305	2.0e-88	319	COG0181	Porphobilinogen deaminase	307
649978206	112	24.79	1	111	8	123	4.0e-12	63.1	COG0073	tRNA-binding EMAP/Myf domain	123
649978208	640	32.65	330	602	1	285	1.0e-40	161	COG0515	Serine/threonine protein kinase	384
649978209	335	39.01	11	230	4	226	1.0e-52	200	COG0571	dsRNA-specific ribonuclease	235
649978210	520	48.01	129	402	66	340	1.0e-66	247	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649978216	316	28.77	164	309	9	154	1.0e-12	67.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649978217	462	47.16	3	456	2	457	0.0e+00	494	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649978219	379	29.1	1	378	10	407	1.0e-53	203	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
649978221	190	19	13	170	3	202	3.0e-07	48.3	COG1335	Nicotinamidase-related amidase	205
649978222	109	39.78	15	105	8	100	1.0e-17	81.5	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
649978224	433	23.03	43	329	14	313	1.0e-25	111	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649978225	495	29.67	80	332	10	279	8.0e-32	132	COG0515	Serine/threonine protein kinase	384
649978226	441	40.18	5	439	2	428	4.0e-115	408	COG0124	Histidyl-tRNA synthetase	429
649978229	237	53.74	6	230	3	225	5.0e-77	280	COG1136	ABC-type lipoprotein export system, ATPase component	226
649978230	541	21.78	27	392	55	347	1.0e-13	71.9	COG1566	Multidrug resistance efflux pump	352
649978233	682	50.14	5	682	4	699	0.0e+00	683	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
649978235	1017	46.88	47	700	1	575	0.0e+00	715	COG0495	Leucyl-tRNA synthetase	814
649978238	500	48.67	15	491	17	501	0.0e+00	552	COG1190	Lysyl-tRNA synthetase (class II)	502
649978240	243	44.93	12	237	2	222	5.0e-70	257	COG1136	ABC-type lipoprotein export system, ATPase component	226
649978241	292	40.07	1	285	2	284	8.0e-67	247	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
649978242	262	51.89	3	262	1	264	9.0e-89	319	COG0413	Ketopantoate hydroxymethyltransferase	268
649978243	109	34.44	17	102	12	101	2.0e-08	50.8	COG1694	NTP pyrophosphatase, house-cleaning of non-canonical NTPs	102
649978244	202	42.23	1	202	1	205	7.0e-44	170	COG0522	Ribosomal protein S4 or related protein	205
649978246	394	28.3	29	382	3	310	5.0e-42	165	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649978249	148	41.89	1	148	1	147	3.0e-20	91	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
649978252	327	25.86	5	324	5	309	2.0e-32	133	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
649978253	174	24.18	13	163	2	117	4.0e-10	57.8	COG0517	CBS domain	117
649978254	724	29.15	132	723	1	516	2.0e-60	227	COG1657	Squalene cyclase	517
649978255	337	47.6	24	335	3	314	2.0e-95	342	COG3252	Methenyltetrahydromethanopterin cyclohydrolase	314
649978258	1315	30.19	1	1304	2	1161	0.0e+00	504	COG1196	Chromosome segregation ATPase	1163
649978259	343	26.79	56	329	36	297	2.0e-13	70.7	COG3547	Transposase	303
649978262	653	44.55	33	653	34	651	0.0e+00	660	COG1166	Arginine decarboxylase (spermidine biosynthesis)	652
649978264	334	18.73	57	303	25	294	3.0e-16	80	COG0657	Acetyl esterase/lipase	312
649978265	486	44.79	1	480	4	459	0.0e+00	468	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649978267	132	24.37	15	132	2	120	1.0e-04	38.9	COG2198	HPt (histidine-containing phosphotransfer) domain	122
649978268	496	49.37	22	495	3	472	0.0e+00	530	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
649978269	358	47.55	6	349	1	347	6.0e-109	387	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
649978270	244	34.17	1	120	1	83	4.0e-16	78.8	COG2088	DNA-binding protein SpoVG, cell septation regulator	95
649978271	297	38.49	6	294	1	282	7.0e-68	250	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
649978273	328	40.88	1	317	8	316	1.0e-52	200	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
649978274	290	32.95	30	290	7	263	5.0e-39	154	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
649978275	476	27.74	1	476	3	455	3.0e-44	173	COG1070	Sugar (pentulose or hexulose) kinase	502
649978276	338	57.65	59	334	5	285	5.0e-98	351	COG2876	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	286
649978278	584	44.81	387	568	5	181	3.0e-41	163	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649978281	486	29.49	26	473	1	475	2.0e-58	220	COG3119	Arylsulfatase A or related enzyme	475
649978282	368	28.65	15	359	2	342	2.0e-41	163	COG0673	Predicted dehydrogenase	342
649978285	426	51.17	1	425	1	424	0.0e+00	540	COG0104	Adenylosuccinate synthase	430
649978286	1596	19.44	514	820	31	304	1.0e-08	56.8	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649978290	324	36.84	7	233	6	230	3.0e-50	192	COG0300	Short-chain dehydrogenase	265
649978291	427	20.6	38	390	1	338	5.0e-29	122	COG0673	Predicted dehydrogenase	342
649978293	332	37.72	1	330	1	324	5.0e-67	248	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
649978296	240	29.72	7	218	1	212	4.0e-33	134	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
649978299	156	29.93	18	151	7	143	5.0e-19	87.2	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
649978300	496	26.48	76	448	2	383	2.0e-42	167	COG0515	Serine/threonine protein kinase	384
649978303	208	26.67	10	204	6	181	9.0e-14	70.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649978311	337	25.18	8	145	1	138	2.0e-08	53.5	COG2165	Type II secretory pathway, pseudopilin PulG	149
649978313	328	21.35	75	243	40	214	7.0e-07	48.4	COG2755	Lysophospholipase L1 or related esterase	216
649978314	345	27.14	9	144	6	141	7.0e-10	58.5	COG2165	Type II secretory pathway, pseudopilin PulG	149
649978316	1184	19.51	55	425	16	396	5.0e-11	64.3	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
649978324	499	23.97	5	476	2	470	5.0e-37	149	COG3349	Uncharacterized conserved protein, contains NAD-binding domain and a Fe-S cluster	485
649978325	464	35.41	1	464	1	427	1.0e-79	291	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
649978328	633	32.62	18	480	5	441	2.0e-61	231	COG0038	H+/Cl- antiporter ClcA	443
649978329	231	26.96	1	225	1	219	3.0e-28	119	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
649978330	140	31.71	9	131	12	131	4.0e-20	90.3	COG0848	Biopolymer transport protein ExbD	137
649978332	503	44	1	497	3	497	0.0e+00	560	COG2317	Zn-dependent carboxypeptidase, M32 family	497
649978335	346	30.17	24	304	9	293	5.0e-32	132	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
649978337	770	22.67	298	763	25	432	7.0e-34	139	COG1030	Membrane-bound serine protease (ClpP class)	436
649978339	413	48.78	1	409	3	389	0.0e+00	475	COG0448	ADP-glucose pyrophosphorylase	393
649978341	338	19.74	1	307	21	309	4.0e-10	59.3	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
649978342	167	28.26	22	159	3	139	8.0e-18	83.4	COG4747	Uncharacterized conserved protein, contains tandem ACT domains	142
649978344	326	24.1	1	278	3	274	1.0e-22	100	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649978346	357	22.34	83	338	52	317	7.0e-09	55.3	COG1566	Multidrug resistance efflux pump	352
649978347	259	37.5	2	256	7	254	4.0e-46	178	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
649978348	341	26.07	8	331	88	408	1.0e-45	177	COG0593	Chromosomal replication initiation ATPase DnaA	408
649978349	221	47.53	1	221	4	226	3.0e-61	228	COG2738	Zn-dependent membrane protease YugP	226
649978352	493	24.63	46	441	11	336	6.0e-38	152	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
649978353	438	51.59	4	438	1	436	0.0e+00	547	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
649978354	390	34.12	160	389	35	284	2.0e-33	136	COG1408	Predicted phosphohydrolase, MPP superfamily	284
649978356	162	29.14	16	159	14	156	3.0e-10	58	COG2042	Ribosome biogenesis protein Tsr3 (rRNA maturation)	179
649978358	913	39.72	62	623	159	709	1.0e-130	461	COG0643	Chemotaxis protein histidine kinase CheA	716
649978359	156	26.85	5	153	4	152	8.0e-24	103	COG0835	Chemotaxis signal transduction protein	165
649978360	829	28.81	531	821	105	406	5.0e-32	133	COG0840	Methyl-accepting chemotaxis protein	408
649978361	670	35.91	41	670	13	650	0.0e+00	468	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
649978362	267	35.58	6	266	2	260	1.0e-45	177	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
649978363	423	23.4	9	397	35	407	1.0e-32	134	COG3875	Nickel-dependent lactate racemase	423
649978366	289	58.93	5	283	2	279	3.0e-107	381	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
649978368	329	36.39	12	304	1	293	1.0e-58	220	COG0109	Polyprenyltransferase (heme O synthase)	304
649978369	329	21.15	9	261	16	283	2.0e-11	63.8	COG1612	Heme A synthase	323
649978370	595	45.36	24	570	4	520	0.0e+00	485	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
649978371	265	28.57	15	252	4	222	2.0e-37	149	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
649978373	471	35.05	9	471	3	454	4.0e-83	302	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
649978379	90	36.26	1	90	2	92	7.0e-13	65.6	COG1254	Acylphosphatase	92
649978381	50	70.73	5	45	7	47	1.0e-08	51.3	COG4338	Uncharacterized protein	54
649978383	736	26.73	33	519	1	452	2.0e-54	207	COG4964	Flp pilus assembly protein, secretin CpaC	455
649978386	405	20.29	134	398	78	334	6.0e-22	98.7	COG0642	Signal transduction histidine kinase	336
649978387	245	37.96	7	244	4	246	1.0e-49	190	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
649978390	150	26.92	1	150	1	153	5.0e-13	67.1	COG4276	Ligand-binding SRPBCC domain	153
649978391	463	38.7	1	455	2	454	5.0e-125	441	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
649978393	1866	17.08	661	1518	172	1009	3.0e-12	69.3	COG1196	Chromosome segregation ATPase	1163
649978396	1226	55.54	330	1195	1	842	0.0e+00	1062	COG1410	Methionine synthase I, cobalamin-binding domain	842
649978397	296	39.07	13	287	15	287	5.0e-61	228	COG0685	5,10-methylenetetrahydrofolate reductase	291
649978399	442	60.75	8	434	4	420	0.0e+00	624	COG0499	S-adenosylhomocysteine hydrolase	420
649978401	397	38.2	19	393	1	354	2.0e-82	299	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
649978402	326	34.76	3	324	2	314	4.0e-52	198	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649978407	392	42.74	34	384	4	344	3.0e-96	345	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
649978411	245	46.88	14	236	2	225	1.0e-68	252	COG1136	ABC-type lipoprotein export system, ATPase component	226
649978412	152	29.82	8	121	1	112	7.0e-21	93.4	COG0824	Acyl-CoA thioesterase FadM	137
649978415	318	26.67	54	275	27	220	4.0e-20	92.7	COG0284	Orotidine-5'-phosphate decarboxylase	240
649978416	597	25.48	30	591	27	595	1.0e-80	294	COG1164	Oligoendopeptidase F	598
649978418	391	36.43	2	389	4	346	3.0e-92	332	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
649978419	1126	25.25	2	1095	1	1006	0.0e+00	565	COG0841	Multidrug efflux pump subunit AcrB	1009
649978421	473	34.89	42	473	1	438	1.0e-71	264	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
649978422	218	39.41	13	214	4	187	2.0e-36	146	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
649978424	369	41.67	100	267	1	167	1.0e-41	164	COG4335	3-methyladenine DNA glycosylase AlkC	167
649978426	450	29.4	21	450	1	419	1.0e-34	141	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649978428	632	38.08	19	615	1	578	0.0e+00	498	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
649978430	715	31.96	10	714	5	715	0.0e+00	574	COG0058	Glucan phosphorylase	750
649978432	384	34.8	3	380	5	412	5.0e-68	251	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
649978435	497	30.22	254	478	1	169	4.0e-30	126	COG0516	IMP dehydrogenase/GMP reductase	170
649978436	305	37.68	20	295	1	254	3.0e-61	228	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
649978438	432	24.8	1	371	1	327	4.0e-30	126	COG0205	6-phosphofructokinase	347
649978441	327	20.16	77	327	11	216	3.0e-05	43.4	COG2755	Lysophospholipase L1 or related esterase	216
649978442	488	62.96	1	486	2	472	0.0e+00	778	COG0362	6-phosphogluconate dehydrogenase	473
649978443	250	24.33	1	248	2	292	8.0e-26	110	COG1234	Ribonuclease BN, tRNA processing enzyme	292
649978446	594	44.67	13	592	1	550	0.0e+00	576	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
649978449	424	23.19	11	353	3	332	3.0e-17	83.3	COG2814	Predicted arabinose efflux permease, MFS family	394
649978451	365	16.56	16	317	2	312	5.0e-09	55.9	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
649978453	344	37.43	1	343	2	350	3.0e-75	275	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
649978454	369	29.54	1	365	1	362	6.0e-47	181	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
649978456	826	53.56	7	564	3	559	0.0e+00	728	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
649978457	198	22.92	13	172	1	191	1.0e-14	73.1	COG0778	Nitroreductase	207
649978458	1194	27.4	2	1166	1	1009	0.0e+00	590	COG0841	Multidrug efflux pump subunit AcrB	1009
649978459	412	22.73	40	329	51	351	7.0e-17	81.9	COG1566	Multidrug resistance efflux pump	352
649978460	314	39.18	10	309	5	316	2.0e-58	219	COG0611	Thiamine monophosphate kinase	317
649978461	496	29.28	26	467	1	472	2.0e-58	220	COG3119	Arylsulfatase A or related enzyme	475
649978462	430	39.95	15	430	8	427	4.0e-117	415	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
649978463	172	60	6	160	3	157	8.0e-56	209	COG0315	Molybdenum cofactor biosynthesis enzyme	157
649978464	66	47.69	1	65	1	65	8.0e-13	65.3	COG1551	sRNA-binding carbon storage regulator CsrA	73
649978466	383	25.57	21	311	12	309	9.0e-27	114	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649978467	369	37.11	8	365	1	388	2.0e-86	312	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
649978470	262	26.64	1	262	1	273	8.0e-42	163	COG0266	Formamidopyrimidine-DNA glycosylase	273
649978472	787	39.74	26	786	3	730	0.0e+00	668	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
649978473	209	22.75	16	204	7	178	3.0e-09	55.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649978474	399	22.07	45	339	28	301	1.0e-10	61.4	COG0385	Predicted Na+-dependent transporter	319
649978475	479	29.53	19	464	18	455	4.0e-52	199	COG0534	Na+-driven multidrug efflux pump	455
649978476	202	41	8	202	3	200	2.0e-46	178	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
649978477	452	22.63	319	435	9	133	3.0e-04	40.2	COG1225	Peroxiredoxin	157
649978478	484	23.81	241	440	69	274	3.0e-04	40.3	COG0294	Dihydropteroate synthase	274
649978479	470	36.94	7	459	7	452	4.0e-112	398	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
649978481	248	30.2	6	238	9	251	7.0e-31	127	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649978482	497	28.48	48	490	1	442	2.0e-72	266	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
649978483	501	32.54	35	306	15	306	6.0e-45	175	COG3386	Sugar lactone lactonase YvrE	307
649978484	402	42.48	19	390	1	374	6.0e-104	371	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649978487	280	36.5	1	271	2	259	4.0e-45	174	COG1192	Cellulose biosynthesis protein BcsQ	259
649978489	442	52.94	45	401	4	355	4.0e-115	408	COG4962	Pilus assembly protein, ATPase of CpaF family	355
649978490	323	28.57	10	323	3	309	1.0e-46	180	COG4965	Flp pilus assembly protein TadB	309
649978491	310	24.6	4	307	7	318	5.0e-17	82.2	COG2064	Pilus assembly protein TadC	320
649978493	66	46.88	1	62	1	64	4.0e-11	59.8	COG1278	Cold shock protein, CspA family	67
649978495	303	26.07	93	294	5	208	2.0e-18	87.1	COG0705	Membrane associated serine protease, rhomboid family	228
649978496	326	44.95	39	315	36	322	1.0e-78	287	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
649978498	179	40.32	56	178	7	130	8.0e-27	113	COG0824	Acyl-CoA thioesterase FadM	137
649978500	148	38.97	1	136	2	117	3.0e-18	84.5	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
649978502	165	47.95	13	158	3	148	4.0e-46	177	COG0691	tmRNA-binding protein	153
649978503	375	43.58	182	360	61	239	4.0e-46	179	COG0805	Sec-independent protein secretion pathway component TatC	255
649978504	496	18.64	161	434	42	304	2.0e-12	67.5	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649978505	299	22.36	39	271	35	273	1.0e-04	40.4	COG5607	CHAD domain (function unknown)	283
649978507	216	24.14	41	214	1	154	3.0e-21	95.3	COG1225	Peroxiredoxin	157
649978508	499	30.41	41	485	1	456	3.0e-59	223	COG3119	Arylsulfatase A or related enzyme	475
649978509	481	26.62	50	422	4	442	4.0e-46	179	COG3119	Arylsulfatase A or related enzyme	475
649978511	345	49.42	7	345	8	351	1.0e-99	356	COG0407	Uroporphyrinogen-III decarboxylase	352
649978512	498	31.57	17	485	1	442	5.0e-77	282	COG1232	Protoporphyrinogen oxidase	444
649978513	473	28.17	91	472	128	499	1.0e-51	197	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649978514	295	49.49	7	295	4	297	3.0e-83	302	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
649978515	306	45.8	11	295	1	286	3.0e-79	289	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
649978516	665	41.38	8	648	1	641	0.0e+00	510	COG0210	Superfamily I DNA or RNA helicase	655
649978517	289	27.08	25	289	2	282	5.0e-29	121	COG0515	Serine/threonine protein kinase	384
649978518	296	57.25	13	288	5	279	2.0e-106	379	COG0777	Acetyl-CoA carboxylase beta subunit	294
649978519	185	37.09	1	147	2	152	1.0e-24	106	COG0406	Broad specificity phosphatase PhoE	208
649978520	230	49.07	15	228	6	220	9.0e-71	260	COG0036	Pentose-5-phosphate-3-epimerase	220
649978521	433	18.73	73	420	14	349	9.0e-13	68.3	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649978522	751	53.58	162	699	54	592	0.0e+00	603	COG0465	ATP-dependent Zn proteases	596
649978524	228	41.67	6	228	3	228	1.0e-55	209	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649978525	225	37.5	1	215	9	224	6.0e-36	144	COG0704	Phosphate uptake regulator	240
649978526	280	65.87	29	280	3	253	9.0e-124	436	COG1117	ABC-type phosphate transport system, ATPase component	253
649978527	347	36.23	13	345	11	292	1.0e-58	220	COG0581	ABC-type phosphate transport system, permease component	292
649978528	317	41.5	15	316	14	310	2.0e-61	229	COG0573	ABC-type phosphate transport system, permease component	310
649978529	336	31.19	6	310	13	316	2.0e-52	199	COG0226	ABC-type phosphate transport system, periplasmic component	318
649978533	310	32	5	300	3	269	1.0e-53	203	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
649978534	454	37.3	22	447	16	426	3.0e-98	352	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
649978537	338	42.94	1	336	1	314	9.0e-82	297	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649978539	620	18.29	365	619	28	349	5.0e-09	56.6	COG1858	Cytochrome c peroxidase	364
649978544	459	58.65	16	459	5	444	0.0e+00	606	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
649978545	188	61.4	15	185	5	175	3.0e-65	241	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
649978546	81	25.76	16	81	7	72	7.0e-04	35.7	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
649978548	406	17.95	55	350	2	291	8.0e-09	55.2	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649978549	126	40.48	1	126	1	126	2.0e-21	94.5	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
649978553	432	26.17	16	426	7	427	3.0e-49	189	COG1253	Hemolysin or related protein, contains CBS domains	429
649978554	330	21.56	1	309	1	318	8.0e-27	114	COG1253	Hemolysin or related protein, contains CBS domains	429
649978556	610	23.87	444	598	2	147	1.0e-07	52	COG1714	Uncharacterized membrane protein YckC, RDD family	172
649978559	179	19.76	8	174	5	130	5.0e-09	54.2	COG1815	Flagellar basal body rod protein FlgB	133
649978560	133	41.18	1	132	3	136	2.0e-31	127	COG1558	Flagellar basal body rod protein FlgC	137
649978561	100	29.11	22	100	27	105	3.0e-09	53.8	COG1677	Flagellar hook-basal body complex protein FliE	105
649978562	540	17.63	4	538	5	544	3.0e-20	93.9	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
649978563	330	47.04	6	324	16	336	1.0e-69	256	COG1536	Flagellar motor switch protein FliG	339
649978564	233	29.1	40	227	43	220	2.0e-12	66.5	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
649978565	442	54.88	8	436	12	441	0.0e+00	560	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
649978571	67	48.28	1	58	1	58	1.0e-11	61	COG1582	Uncharacterized protein YlzI, FlbEa/FlbD family	67
649978572	258	40.7	1	257	1	257	4.0e-62	231	COG1291	Flagellar motor component MotA	266
649978573	242	24.29	1	235	1	240	2.0e-23	102	COG1360	Flagellar motor protein MotB	244
649978576	361	21.48	165	297	1	127	2.0e-05	43.8	COG3190	Flagellar biogenesis protein FliO	137
649978577	340	46.61	74	320	20	248	8.0e-63	234	COG1338	Flagellar biosynthetic protein FliP	248
649978578	88	46.51	1	86	1	86	9.0e-14	68.6	COG1987	Flagellar biosynthesis protein FliQ	89
649978579	330	24.92	27	323	10	252	7.0e-25	108	COG1684	Flagellar biosynthesis protein FliR	258
649978580	357	39.78	1	357	1	357	6.0e-99	354	COG1377	Flagellar biosynthesis protein FlhB	363
649978583	637	31.65	1	610	1	519	3.0e-97	349	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
649978584	283	45.52	5	278	4	279	2.0e-72	266	COG1091	dTDP-4-dehydrorhamnose reductase	281
649978585	560	31.93	22	533	2	472	7.0e-98	351	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
649978586	527	32.76	1	519	7	471	1.0e-102	367	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
649978587	848	27.18	1	833	6	858	8.0e-121	428	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
649978588	228	31.15	4	228	8	251	3.0e-33	135	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
649978590	702	41.57	389	564	5	180	2.0e-37	151	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649978591	279	23.56	95	272	52	227	1.0e-15	77.6	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
649978592	437	21.96	44	411	3	342	1.0e-24	108	COG0673	Predicted dehydrogenase	342
649978593	125	34.83	30	117	10	98	1.0e-07	49	COG0640	DNA-binding transcriptional regulator, ArsR family	110
649978594	180	36.7	1	108	4	110	1.0e-17	83	COG0607	Rhodanese-related sulfurtransferase	110
649978595	464	26	1	225	12	249	6.0e-19	89.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
649978596	297	31.76	8	262	14	253	3.0e-17	82.8	COG0730	Uncharacterized membrane protein YfcA	258
649978597	478	27.16	9	224	20	247	9.0e-17	81.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
649978599	394	20.61	6	344	1	334	1.0e-29	124	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
649978600	357	44.55	38	328	55	356	4.0e-75	275	COG1858	Cytochrome c peroxidase	364
649978601	358	29.03	262	354	28	110	1.0e-04	41.4	COG1416	Intracellular sulfur oxidation protein, DsrE/DsrF family	112
649978602	501	27.69	37	490	2	453	2.0e-53	203	COG3119	Arylsulfatase A or related enzyme	475
649978603	208	21.21	11	194	1	196	3.0e-07	48.7	COG2928	Uncharacterized membrane protein	222
649978605	415	55.53	1	414	1	412	0.0e+00	499	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
649978606	76	60.53	1	76	4	79	1.0e-10	57.6	COG0236	Acyl carrier protein	80
649978612	188	36.17	8	184	2	188	2.0e-31	129	COG0693	Putative intracellular protease/amidase	188
649978613	304	45.57	1	304	1	303	1.0e-83	302	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
649978614	333	43.75	1	329	2	333	3.0e-92	332	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
649978615	59	47.37	1	57	1	57	4.0e-10	56.4	COG0333	Ribosomal protein L32	57
649978616	410	39.49	77	388	2	288	3.0e-66	246	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
649978619	323	25.86	7	122	7	113	1.0e-08	54.3	COG2165	Type II secretory pathway, pseudopilin PulG	149
649978620	56	35.29	6	56	15	63	2.0e-06	44.2	COG4256	Hemin uptake protein HemP	63
649978621	350	45.51	7	350	1	328	5.0e-100	357	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
649978625	368	35.99	1	339	1	327	7.0e-72	264	COG1868	Flagellar motor switch protein FliM	332
649978626	422	56.72	15	422	8	416	0.0e+00	556	COG0014	Gamma-glutamyl phosphate reductase	417
649978628	220	41.5	5	204	4	202	8.0e-47	180	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
649978629	351	52.6	24	350	7	332	5.0e-115	407	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
649978630	1184	30.42	661	1173	32	527	4.0e-76	280	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
649978633	519	29.9	227	513	2	274	3.0e-35	143	COG0388	Predicted amidohydrolase	274
649978635	557	46.32	4	539	1	530	0.0e+00	549	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
649978636	467	35.58	50	462	30	408	1.0e-77	284	COG0498	Threonine synthase	411
649978638	441	17.97	6	389	41	400	3.0e-19	89.9	COG1524	Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily	450
649978639	354	52.59	7	354	3	343	1.0e-128	452	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
649978641	121	37.14	6	121	9	143	7.0e-18	82.7	COG3296	Uncharacterized conserved protein, Tic20 family	143
649978642	252	32.34	7	203	12	201	2.0e-29	123	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
649978644	534	24.36	291	524	2	211	8.0e-19	89.1	COG2114	Adenylate cyclase, class 3	227
649978645	952	44.99	18	891	5	800	0.0e+00	864	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
649978646	371	30.75	19	371	14	381	6.0e-39	155	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649978647	160	25.15	1	159	2	163	3.0e-21	94.7	COG0622	Predicted phosphodiesterase	172
649978648	431	24.88	2	423	1	368	9.0e-53	201	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
649978650	564	47.07	61	555	5	493	0.0e+00	523	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649978651	371	50.71	4	353	3	353	1.0e-120	426	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
649978652	569	47.51	61	563	2	498	0.0e+00	529	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649978653	416	40.38	1	416	1	397	2.0e-96	346	COG1459	Type II secretory pathway, component PulF	397
649978664	312	40.13	1	299	3	316	3.0e-59	222	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
649978665	515	31.49	48	335	1	305	6.0e-43	168	COG0515	Serine/threonine protein kinase	384
649978671	494	44.47	84	492	5	409	3.0e-109	389	COG0004	Ammonia channel protein AmtB	409
649978672	112	71.43	1	112	1	112	4.0e-35	139	COG0347	Nitrogen regulatory protein PII	112
649978673	419	33.42	66	408	26	353	3.0e-63	236	COG1858	Cytochrome c peroxidase	364
649978674	869	47.47	1	868	6	879	0.0e+00	922	COG0013	Alanyl-tRNA synthetase	879
649978675	407	20.94	112	378	56	316	9.0e-12	64.9	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649978677	333	51.04	7	332	6	335	2.0e-107	382	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
649978678	118	44.44	1	117	2	118	3.0e-26	110	COG0292	Ribosomal protein L20	118
649978679	143	46.88	78	141	1	64	3.0e-11	61.4	COG0291	Ribosomal protein L35	65
649978680	151	57.24	1	151	23	173	2.0e-47	181	COG0290	Translation initiation factor IF-3	176
649978683	346	34.55	63	332	3	272	1.0e-49	190	COG0388	Predicted amidohydrolase	274
649978685	271	41.18	11	265	11	265	2.0e-55	208	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
649978686	262	41.5	1	253	6	250	5.0e-74	270	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
649978687	397	21.24	1	302	1	290	3.0e-19	89.8	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
649978690	313	33.98	7	312	1	297	2.0e-60	226	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
649978691	495	34.59	23	495	5	458	2.0e-93	336	COG0773	UDP-N-acetylmuramate-alanine ligase	459
649978692	294	41.55	12	293	4	287	9.0e-78	283	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
649978697	407	30.1	1	404	19	407	3.0e-63	236	COG2124	Cytochrome P450	411
649978699	427	36.33	4	254	5	253	5.0e-52	199	COG0631	Serine/threonine protein phosphatase PrpC	262
649978700	261	39.26	1	240	1	226	5.0e-51	194	COG2013	Uncharacterized conserved protein, AIM24 family	227
649978701	614	34.99	1	476	1	460	2.0e-103	370	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
649978703	126	62.3	5	126	3	124	9.0e-45	172	COG3651	Uncharacterized conserved protein, DUF2237 family	125
649978706	400	46.82	10	400	15	404	5.0e-119	421	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
649978707	314	36.93	1	313	4	321	2.0e-60	226	COG0142	Geranylgeranyl pyrophosphate synthase	322
649978708	638	49.6	3	629	2	624	0.0e+00	732	COG1154	Deoxyxylulose-5-phosphate synthase	627
649978711	277	40.82	5	271	3	264	1.0e-64	240	COG1606	ATP-utilizing enzyme, PP-loop superfamily	269
649978713	373	28.76	3	366	6	382	2.0e-47	183	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
649978716	459	16.74	6	442	1	441	2.0e-09	57.4	COG3014	Uncharacterized protein	449
649978719	1129	19.71	2	1100	3	1096	1.0e-56	215	COG3857	ATP-dependent helicase/DNAse subunit B	1108
649978720	1168	22.98	1	1111	2	1117	4.0e-100	360	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
649978724	399	28.14	10	341	2	306	8.0e-45	174	COG0673	Predicted dehydrogenase	342
649978726	477	47.28	10	468	6	454	0.0e+00	474	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649978729	512	40.92	182	496	74	395	5.0e-74	272	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
649978730	262	26.32	57	240	25	207	2.0e-16	79.9	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
649978731	995	38.57	510	986	5	469	1.0e-124	441	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
649978732	324	24.76	16	322	35	312	1.0e-29	123	COG1899	Deoxyhypusine synthase	318
649978733	165	34.27	10	152	1	140	4.0e-28	117	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
649978736	835	51.61	1	707	10	694	0.0e+00	829	COG1523	Pullulanase/glycogen debranching enzyme	697
649978737	210	50.75	1	200	1	192	3.0e-65	241	COG0307	Riboflavin synthase alpha chain	204
649978739	388	23.51	57	340	67	379	8.0e-21	95	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649978746	454	20.95	78	424	39	339	1.0e-23	104	COG0673	Predicted dehydrogenase	342
649978747	356	27.03	34	317	31	325	2.0e-41	163	COG3608	Predicted deacylase	331
649978748	401	31.65	1	290	1	315	2.0e-56	213	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
649978752	530	24.24	157	514	4	333	2.0e-36	147	COG0642	Signal transduction histidine kinase	336
649978755	573	30.53	1	262	9	269	4.0e-25	110	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
649978756	331	46.32	1	324	6	330	5.0e-82	297	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
649978757	798	32.88	287	795	210	700	4.0e-98	353	COG1480	Membrane-associated HD superfamily phosphohydrolase	700
649978758	162	33.77	5	154	1	150	1.0e-23	102	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
649978762	534	23.17	201	442	38	255	3.0e-12	67	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
649978765	155	59.26	2	136	1	135	3.0e-52	197	COG0105	Nucleoside diphosphate kinase	135
649978766	386	57.48	4	382	3	368	0.0e+00	535	COG0505	Carbamoylphosphate synthase small subunit	368
649978767	136	32.69	23	126	3	106	6.0e-11	59.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
649978768	485	30.79	27	447	4	442	1.0e-63	237	COG3119	Arylsulfatase A or related enzyme	475
649978770	426	18.75	1	395	10	431	2.0e-20	94.2	COG1904	Glucuronate isomerase	463
649978771	733	50.63	21	724	6	693	0.0e+00	786	COG0480	Translation elongation factor EF-G, a GTPase	697
649978772	285	24.18	20	273	24	279	4.0e-19	88.9	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
649978773	167	33.93	18	128	11	115	2.0e-19	88.5	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
649978775	493	36.93	25	421	28	381	1.0e-81	297	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
649978776	341	50.15	4	338	2	332	3.0e-106	378	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
649978780	329	29.69	7	326	9	314	2.0e-45	176	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
649978781	523	30.02	8	464	1	447	4.0e-60	226	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
649978782	706	47.39	5	686	1	688	0.0e+00	761	COG0855	Polyphosphate kinase	696
649978785	324	55.33	9	307	4	294	2.0e-83	302	COG4864	Uncharacterized protein YqfA, UPF0365 family	328
649978788	206	36.56	16	201	1	176	1.0e-28	119	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649978791	585	44.83	4	573	5	571	0.0e+00	463	COG3263	NhaP-type Na+/H+ and K+/H+ antiporter with C-terminal TrkAC and CorC domains	574
649978792	485	33.89	39	481	2	471	8.0e-68	251	COG3119	Arylsulfatase A or related enzyme	475
649978795	357	58.84	17	289	8	276	9.0e-76	277	COG0468	RecA/RadA recombinase	279
649978796	126	28.4	17	97	3	81	2.0e-06	45	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
649978797	665	19.03	1	344	5	371	9.0e-06	45.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649978799	264	25.19	1	256	3	262	1.0e-14	73.8	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
649978810	370	27.88	8	365	8	401	1.0e-42	167	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
649978811	1090	66.84	13	407	1	393	0.0e+00	553	COG0458	Carbamoylphosphate synthase large subunit	400
649978812	493	23.08	38	425	2	336	1.0e-34	141	COG0673	Predicted dehydrogenase	342
649978814	283	47.79	8	279	1	268	3.0e-85	308	COG2107	Predicted periplasmic solute-binding protein	272
649978815	541	47.86	27	535	8	507	0.0e+00	541	COG0029	Aspartate oxidase	518
649978816	259	42.91	10	257	1	251	3.0e-47	182	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649978817	203	25.66	1	149	1	150	7.0e-11	60.7	COG1406	Chemotaxis protein CheX, a CheY~P-specific phosphatase	153
649978818	462	44.48	160	458	1	296	3.0e-86	312	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
649978819	263	22.9	52	263	10	209	7.0e-13	68	COG2755	Lysophospholipase L1 or related esterase	216
649978820	365	26.03	61	347	88	369	1.0e-34	140	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649978822	241	58.42	43	241	4	201	1.0e-74	272	COG0605	Superoxide dismutase	204
649978824	525	35.63	3	420	2	409	3.0e-92	333	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
649978826	911	17.1	293	773	30	492	5.0e-16	80.4	COG3225	ABC-type uncharacterized transport system involved in gliding motility, auxiliary component	538
649978827	257	43.29	20	247	3	233	1.0e-65	243	COG1131	ABC-type multidrug transport system, ATPase component	293
649978830	434	39.91	3	430	2	428	1.0e-107	383	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
649978831	331	48.39	14	314	4	310	7.0e-99	354	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
649978833	65	47.76	1	65	1	67	4.0e-12	62.8	COG1278	Cold shock protein, CspA family	67
649978834	80	42.86	12	74	11	73	5.0e-13	66	COG2501	Ribosome-associated protein YbcJ, S4-like RNA binding protein	73
649978835	330	18.03	4	292	23	309	2.0e-15	77.1	COG3239	Fatty acid desaturase	343
649978836	486	19.78	36	469	7	435	1.0e-08	55.3	COG4908	Uncharacterized protein, contains a NRPS condensation (elongation) domain	439
649978837	244	29.82	12	239	9	207	6.0e-26	111	COG0400	Predicted esterase	207
649978838	560	33.33	15	528	4	516	1.0e-105	377	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
649978839	313	38.69	1	304	1	303	1.0e-75	276	COG0196	FAD synthase	304
649978841	247	31.47	1	237	10	258	4.0e-30	125	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
649978842	418	33.41	4	418	3	379	9.0e-70	257	COG2046	ATP sulfurylase (sulfate adenylyltransferase)	397
649978843	348	41.08	4	347	6	349	2.0e-79	289	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
649978848	180	50.27	1	180	1	182	3.0e-63	234	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
649978849	313	27.71	15	307	6	290	1.0e-34	140	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
649978850	463	30.66	30	451	1	467	7.0e-67	248	COG3119	Arylsulfatase A or related enzyme	475
649978852	315	49.16	16	312	1	297	3.0e-84	305	COG2037	Formylmethanofuran:tetrahydromethanopterin formyltransferase	297
649978853	234	41.92	29	226	4	201	5.0e-54	204	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
649978854	153	28.77	8	153	1	128	3.0e-13	68	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
649978856	742	38.61	5	706	7	704	0.0e+00	530	COG0557	Exoribonuclease R	706
649978857	323	29.28	14	314	1	287	5.0e-43	168	COG3481	3'-5' exoribonuclease YhaM, can participate in 23S rRNA maturation,  HD superfamily	287
649978858	578	43.03	1	563	1	496	0.0e+00	513	COG0442	Prolyl-tRNA synthetase	500
649978861	378	29.26	3	378	2	340	5.0e-55	208	COG0673	Predicted dehydrogenase	342
649978862	160	43.14	6	158	1	150	3.0e-28	118	COG0782	Transcription elongation factor, GreA/GreB family	151
649978864	673	38.71	167	668	34	559	9.0e-111	394	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
649978866	409	48.28	5	409	5	410	0.0e+00	467	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
649978870	349	58.02	9	345	1	340	0.0e+00	498	COG1088	dTDP-D-glucose 4,6-dehydratase	340
649978871	436	54.42	1	418	1	414	0.0e+00	553	COG1004	UDP-glucose 6-dehydrogenase	414
649978872	373	59	126	364	1	237	6.0e-83	301	COG1186	Protein chain release factor B	239
649978874	391	22.28	15	391	12	412	2.0e-35	143	COG2195	Di- or tripeptidase	414
649978876	408	28.69	48	405	2	355	5.0e-57	215	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
649978877	408	36.76	10	407	5	401	1.0e-93	336	COG0162	Tyrosyl-tRNA synthetase	401
649978878	356	32.29	1	348	2	342	2.0e-59	222	COG0673	Predicted dehydrogenase	342
649978879	321	28.62	7	314	14	308	9.0e-42	164	COG1560	Lauroyl/myristoyl acyltransferase	308
649978880	103	36	5	100	8	106	9.0e-18	81.9	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
649978883	326	44.71	1	207	5	211	2.0e-59	223	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
649978884	299	34.86	20	296	2	279	2.0e-57	216	COG0287	Prephenate dehydrogenase	279
649978885	849	53.64	4	813	1	776	0.0e+00	908	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
649978889	426	62.69	23	415	1	391	0.0e+00	579	COG1219	ATP-dependent protease Clp, ATPase subunit	408
649978892	479	31.63	82	353	2	292	8.0e-39	155	COG0515	Serine/threonine protein kinase	384
649978897	131	30.71	3	128	1	120	5.0e-13	66.7	COG3293	Transposase	124
649978898	133	26.32	54	129	4	70	2.0e-04	38.4	COG2608	Copper chaperone CopZ	71
649978899	946	29.97	76	345	1	284	2.0e-40	161	COG0515	Serine/threonine protein kinase	384
649978901	418	26.85	115	412	89	376	8.0e-25	108	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649978902	459	52.1	1	450	1	422	0.0e+00	545	COG0151	Phosphoribosylamine-glycine ligase	428
649978904	193	39.69	1	192	2	191	2.0e-45	175	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
649978905	366	31.17	3	363	19	399	4.0e-69	255	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
649978906	234	35.08	15	200	19	205	2.0e-26	112	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
649978907	239	28.81	50	219	5	181	1.0e-17	83.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649978909	416	40.53	40	414	124	499	4.0e-90	325	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649978910	337	24.57	1	333	52	392	2.0e-30	126	COG1459	Type II secretory pathway, component PulF	397
649978911	402	29.1	1	399	1	394	2.0e-51	196	COG1459	Type II secretory pathway, component PulF	397
649978912	381	23.62	37	378	67	394	1.0e-20	94.1	COG1459	Type II secretory pathway, component PulF	397
649978919	486	23.85	131	483	1	361	3.0e-34	139	COG0515	Serine/threonine protein kinase	384
649978920	302	22.33	5	297	1	234	2.0e-10	60.5	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
649978921	525	25.8	164	506	7	329	1.0e-32	134	COG2855	Uncharacterized membrane protein YadS	334
649978923	133	37.35	36	118	9	91	3.0e-13	67.6	COG3326	Uncharacterized membrane protein YsdA, DUF1294 family	94
649978924	377	45.54	150	370	1	217	4.0e-55	209	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
649978926	863	38.82	12	857	6	912	0.0e+00	781	COG0178	Excinuclease UvrABC ATPase subunit	935
649978927	340	29.97	13	337	41	364	7.0e-32	131	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
649978928	179	33.12	1	160	1	157	4.0e-27	114	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
649978930	234	25.37	1	202	2	163	5.0e-14	71.6	COG0622	Predicted phosphodiesterase	172
649978934	406	50.49	33	235	1	203	2.0e-65	243	COG2518	Protein-L-isoaspartate O-methyltransferase	209
649978936	544	39.82	1	536	2	561	0.0e+00	474	COG1229	Formylmethanofuran dehydrogenase subunit A	575
649978939	86	25.3	5	85	21	102	2.0e-04	37.2	COG3162	Uncharacterized membrane protein, DUF485 family	102
649978940	174	40.41	16	161	2	146	5.0e-38	150	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
649978941	429	35.07	7	426	3	407	2.0e-77	282	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
649978942	651	27.32	1	592	1	513	2.0e-86	313	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
649978943	325	39.62	1	313	3	279	7.0e-83	301	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
649978944	167	34.27	1	140	1	143	3.0e-29	121	COG2062	Phosphohistidine phosphatase SixA	163
649978945	267	25	12	267	12	247	2.0e-18	86.6	COG1587	Uroporphyrinogen-III synthase	248
649978947	230	50.23	14	228	6	222	2.0e-59	222	COG0283	Cytidylate kinase	222
649978948	318	30.6	1	317	4	312	3.0e-40	159	COG0385	Predicted Na+-dependent transporter	319
649978949	253	42.98	12	252	2	238	2.0e-63	235	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
649978950	211	47.83	5	211	3	190	7.0e-66	243	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
649978952	134	38.46	3	131	2	129	1.0e-19	89.2	COG1259	Bifunctional DNase/RNase	151
649978955	95	25	16	95	11	90	1.0e-07	48.3	COG2921	Putative lipoic acid-binding regulatory protein	90
649978957	341	44.02	8	212	2	210	3.0e-62	232	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
649978958	626	31.33	249	621	6	359	2.0e-61	230	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
649978959	354	28.21	109	340	1	223	2.0e-22	100	COG0569	Trk K+ transport system, NAD-binding component	225
649978960	395	54.85	1	390	1	381	0.0e+00	483	COG0045	Succinyl-CoA synthetase, beta subunit	387
649978961	532	29.17	23	409	1	424	2.0e-47	183	COG3119	Arylsulfatase A or related enzyme	475
649978962	299	65.67	1	299	1	293	6.0e-110	390	COG0074	Succinyl-CoA synthetase, alpha subunit	293
649978965	638	32.26	31	609	3	547	6.0e-90	325	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
649978966	252	27.31	1	247	1	234	8.0e-31	127	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
649978967	364	44.89	1	364	5	376	2.0e-107	382	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
649978968	274	39.92	3	242	2	246	9.0e-42	163	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649978969	449	22.8	4	370	1	383	7.0e-34	138	COG0515	Serine/threonine protein kinase	384
649978970	333	52.72	6	317	5	317	1.0e-113	403	COG0825	Acetyl-CoA carboxylase alpha subunit	317
649978975	343	48.98	7	343	2	344	3.0e-112	398	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
649978977	388	29.46	6	386	18	404	2.0e-59	223	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
649978979	369	19.77	1	164	2	173	3.0e-11	63	COG1286	Uncharacterized membrane protein, required for colicin V production	182
649978980	350	41.4	6	345	9	343	2.0e-90	326	COG2957	Agmatine/peptidylarginine deiminase	346
649978981	296	36.75	10	289	5	274	4.0e-55	208	COG0388	Predicted amidohydrolase	274
649978984	397	36.47	48	393	1	338	3.0e-56	212	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649978985	123	23.77	1	122	1	117	3.0e-04	37.3	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
649978987	420	59.22	9	419	4	413	0.0e+00	628	COG0112	Glycine/serine hydroxymethyltransferase	413
649978989	276	29.58	10	253	1	281	1.0e-28	120	COG0515	Serine/threonine protein kinase	384
649978990	450	23.89	31	431	1	443	3.0e-40	159	COG3119	Arylsulfatase A or related enzyme	475
649978992	714	45.64	313	596	2	285	5.0e-79	289	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
649978993	455	37.04	13	432	5	388	7.0e-75	274	COG0183	Acetyl-CoA acetyltransferase	392
649978994	325	32.7	1	309	1	299	2.0e-53	202	COG1482	Mannose-6-phosphate isomerase, class I	312
649978995	362	31.9	15	356	1	334	2.0e-55	209	COG0859	ADP-heptose:LPS heptosyltransferase	334
649978996	888	30.09	8	880	5	867	0.0e+00	472	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
649978997	112	71.43	1	112	1	112	7.0e-38	148	COG0347	Nitrogen regulatory protein PII	112
649978998	470	53.7	49	467	1	402	2.0e-121	429	COG0004	Ammonia channel protein AmtB	409
649979002	356	20.38	1	348	2	369	8.0e-23	101	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
649979006	179	45.28	25	175	2	158	1.0e-40	159	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
649979007	263	35.65	6	231	12	240	2.0e-43	169	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
649979010	231	60.43	45	230	9	195	4.0e-74	270	COG0302	GTP cyclohydrolase I	195
649979012	427	22.84	7	345	1	388	7.0e-21	95.5	COG1233	Phytoene dehydrogenase-related protein	487
649979014	223	19.57	1	184	5	188	2.0e-11	63.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649979016	1087	24.22	3	1079	1	1009	0.0e+00	548	COG0841	Multidrug efflux pump subunit AcrB	1009
649979018	191	29.57	9	191	2	179	2.0e-22	98.8	COG1514	2'-5' RNA ligase	180
649979019	348	29.68	131	348	4	219	1.0e-29	124	COG0569	Trk K+ transport system, NAD-binding component	225
649979022	543	30.86	63	384	21	333	4.0e-43	169	COG0642	Signal transduction histidine kinase	336
649979023	482	27.12	28	366	1	424	7.0e-45	175	COG3119	Arylsulfatase A or related enzyme	475
649979026	329	30.98	6	329	2	312	3.0e-57	215	COG0039	Malate/lactate dehydrogenase	313
649979029	440	29.5	21	414	6	399	4.0e-55	209	COG1078	HD superfamily phosphohydrolase	421
649979031	538	64.23	2	535	1	533	0.0e+00	857	COG0504	CTP synthase (UTP-ammonia lyase)	533
649979032	258	42.75	1	252	2	243	3.0e-68	251	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
649979033	641	23.39	303	637	78	393	2.0e-28	121	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
649979034	353	37.95	14	319	5	332	9.0e-78	284	COG3049	Penicillin V acylase or related amidase, Ntn superfamily	353
649979036	120	38.54	19	114	1	95	1.0e-21	95.4	COG2154	Pterin-4a-carbinolamine dehydratase	101
649979039	427	48.11	1	423	1	409	6.0e-129	454	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
649979040	164	36.29	6	126	22	145	2.0e-21	95.3	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
649979041	129	41.67	4	63	3	62	7.0e-09	53	COG0236	Acyl carrier protein	80
649979042	251	46.06	1	247	1	251	7.0e-55	207	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649979043	167	35.25	3	122	19	140	1.0e-19	89.5	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
649979044	420	26.89	194	416	53	314	7.0e-22	98.7	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649979045	292	27.07	27	292	4	260	9.0e-31	127	COG3694	ABC-type uncharacterized transport system, permease component	260
649979046	349	53.45	1	348	1	341	2.0e-115	409	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
649979047	358	36.42	42	336	16	311	2.0e-54	206	COG0616	Periplasmic serine protease, ClpP class	317
649979053	443	25.55	49	364	2	280	2.0e-33	136	COG0673	Predicted dehydrogenase	342
649979055	779	26.45	34	532	24	517	2.0e-68	254	COG0659	Sulfate permease or related transporter, MFS superfamily	554
649979061	260	27.2	6	126	2	123	1.0e-14	74	COG3293	Transposase	124
649979062	566	37.4	169	421	91	335	2.0e-39	157	COG0642	Signal transduction histidine kinase	336
649979064	198	27.84	15	188	1	176	4.0e-16	78.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649979065	377	26.89	12	129	3	120	3.0e-08	53.5	COG2165	Type II secretory pathway, pseudopilin PulG	149
649979070	329	20.06	22	309	1	260	1.0e-04	40.6	COG0708	Exonuclease III	261
649979072	325	45.25	26	321	3	304	2.0e-72	266	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
649979073	472	27.27	162	455	54	365	5.0e-31	129	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649979074	403	21.5	61	397	7	386	2.0e-24	106	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649979075	524	27.07	26	458	1	443	3.0e-47	183	COG3119	Arylsulfatase A or related enzyme	475
649979076	515	25.49	23	476	1	471	5.0e-44	172	COG3119	Arylsulfatase A or related enzyme	475
649979078	424	22.99	45	382	3	328	7.0e-28	118	COG0673	Predicted dehydrogenase	342
649979079	471	28.16	25	443	1	446	3.0e-47	183	COG3119	Arylsulfatase A or related enzyme	475
649979080	486	30.79	26	463	1	469	4.0e-68	252	COG3119	Arylsulfatase A or related enzyme	475
649979081	453	31.94	32	436	1	456	7.0e-59	221	COG3119	Arylsulfatase A or related enzyme	475
649979082	447	29.96	23	426	1	452	2.0e-55	210	COG3119	Arylsulfatase A or related enzyme	475
649979084	320	28.46	8	124	5	127	2.0e-10	59.7	COG2165	Type II secretory pathway, pseudopilin PulG	149
649979085	175	24.42	1	169	11	182	2.0e-16	79	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649979087	499	18.69	88	405	41	317	7.0e-07	49.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649979088	1043	37.66	1	1029	1	1017	0.0e+00	906	COG3696	Cu/Ag efflux pump CusA	1027
649979092	245	23.81	1	223	1	195	7.0e-09	54.5	COG2910	Putative NADH-flavin reductase	211
649979096	178	27.27	1	173	5	180	5.0e-16	77.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649979098	419	42.45	11	394	5	337	3.0e-83	302	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
649979099	143	32.39	2	137	1	139	2.0e-25	108	COG0394	Protein-tyrosine-phosphatase	139
649979116	504	20.23	35	279	32	279	3.0e-03	37.2	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
649979117	1061	37.38	30	1049	3	1061	0.0e+00	1009	COG0587	DNA polymerase III, alpha subunit	1139
649979118	301	21.76	62	267	7	223	1.0e-03	37.9	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
649979119	256	33.98	1	254	2	253	9.0e-49	187	COG3228	Mlc titration factor MtfA, regulates ptsG expression	266
649979120	271	61.95	12	237	42	267	1.0e-91	329	COG2326	Polyphosphate kinase 2, PPK2 family	270
649979121	606	44.85	37	549	22	529	0.0e+00	674	COG1155	Archaeal/vacuolar-type H+-ATPase catalytic subunit A/Vma1	588
649979123	217	25.47	9	216	1	194	4.0e-04	38.4	COG1390	Archaeal/vacuolar-type H+-ATPase subunit E/Vma4	194
649979125	617	22.81	1	610	1	651	2.0e-57	217	COG1269	Archaeal/vacuolar-type H+-ATPase subunit I/STV1	660
649979126	207	24.64	1	199	2	208	1.0e-18	86.9	COG1394	Archaeal/vacuolar-type H+-ATPase subunit D/Vma8	211
649979127	455	41.69	11	439	7	457	0.0e+00	488	COG1156	Archaeal/vacuolar-type H+-ATPase subunit B/Vma2	463
649979128	781	31.51	385	741	1	362	1.0e-63	238	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
649979132	465	37.35	3	420	1	424	2.0e-68	253	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
649979134	707	23.55	6	307	7	290	5.0e-15	77	COG5276	Uncharacterized conserved protein	370
649979135	658	34.94	32	631	89	707	3.0e-129	456	COG2217	Cation transport ATPase	713
649979141	482	24.66	15	436	9	447	9.0e-39	155	COG0591	Na+/proline symporter	493
649979142	807	38.07	10	572	9	568	5.0e-103	369	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
649979143	137	26.09	1	136	16	153	2.0e-07	48.1	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
649979144	115	46.85	1	111	1	110	4.0e-23	99	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
649979145	543	36.71	7	501	5	500	3.0e-74	273	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
649979146	157	49.68	1	157	2	158	1.0e-35	142	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
649979147	109	48.19	23	105	3	85	1.0e-08	51.3	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
649979148	119	45	5	102	7	106	5.0e-19	86.4	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
649979149	156	40.13	1	156	3	159	3.0e-28	117	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
649979150	686	23.1	66	655	37	620	7.0e-66	245	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
649979151	433	16.2	60	252	10	211	1.0e-04	41.4	COG2755	Lysophospholipase L1 or related esterase	216
649979152	55	48.89	1	45	1	45	3.0e-08	50.2	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
649979153	820	36.97	95	809	2	704	0.0e+00	535	COG2217	Cation transport ATPase	713
649979154	279	29.91	10	220	6	215	9.0e-25	107	COG2836	Sulfite exporter TauE/SafE	232
649979155	182	18.66	24	157	20	145	8.0e-05	40.4	COG5456	Nitrogen fixation protein FixH	166
649979156	460	31.81	27	395	1	353	4.0e-47	182	COG0348	Polyferredoxin	386
649979159	771	60.29	26	497	7	480	0.0e+00	639	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
649979160	446	45.43	2	445	1	457	6.0e-125	441	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649979164	343	23.18	53	281	5	223	5.0e-16	79	COG1216	Glycosyltransferase, GT2 family	305
649979167	325	20.73	79	279	41	311	1.0e-17	84.3	COG5039	Exopolysaccharide biosynthesis protein EpsI, predicted pyruvyl transferase	339
649979169	334	30.07	7	148	6	143	3.0e-10	59.7	COG2165	Type II secretory pathway, pseudopilin PulG	149
649979172	355	31.86	12	315	5	314	2.0e-37	150	COG1397	ADP-ribosylglycohydrolase	314
649979178	462	42.27	1	462	2	463	3.0e-122	432	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649979180	138	35.34	2	130	19	151	5.0e-18	83.4	COG0782	Transcription elongation factor, GreA/GreB family	151
649979183	260	37.97	13	249	1	237	5.0e-50	191	COG1414	DNA-binding transcriptional regulator, IclR family	246
649979186	449	25.76	25	416	1	437	1.0e-42	167	COG3119	Arylsulfatase A or related enzyme	475
649979189	332	27.87	46	329	3	278	5.0e-32	131	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
649979191	1165	21.53	821	963	20	145	5.0e-06	47.6	COG2010	Cytochrome c, mono- and diheme variants	150
649979192	491	26.96	20	413	1	468	1.0e-50	194	COG3119	Arylsulfatase A or related enzyme	475
649979193	1036	24.05	15	1027	3	1009	0.0e+00	547	COG0841	Multidrug efflux pump subunit AcrB	1009
649979194	413	23.29	19	379	3	353	4.0e-16	79.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649979195	536	28.63	84	526	1	454	8.0e-51	195	COG1538	Outer membrane protein TolC	457
649979199	600	24.89	32	442	7	454	6.0e-40	159	COG3119	Arylsulfatase A or related enzyme	475
649979207	441	28.76	6	143	7	158	1.0e-08	55	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
649979212	404	22.85	15	272	61	322	6.0e-18	85.4	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
649979212	404	37.84	285	395	17	127	5.0e-21	95.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649979219	210	33.49	1	197	1	198	2.0e-34	138	COG2135	Putative SOS response-associated peptidase YedK	226
649979220	184	26.79	16	181	15	182	2.0e-16	79.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649979230	389	20.47	5	388	3	407	3.0e-17	83	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649979233	243	47.79	3	227	1	226	2.0e-72	265	COG1136	ABC-type lipoprotein export system, ATPase component	226
649979234	380	19.05	1	378	2	406	2.0e-19	90.7	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649979236	500	29.19	1	357	7	364	5.0e-45	175	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649979240	498	28.83	30	470	4	460	1.0e-59	224	COG3119	Arylsulfatase A or related enzyme	475
649979241	433	39.27	10	197	5	195	5.0e-36	145	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
649979242	509	28.27	8	465	2	458	9.0e-85	308	COG1070	Sugar (pentulose or hexulose) kinase	502
649979245	423	59.67	5	423	2	419	0.0e+00	609	COG4806	L-rhamnose isomerase	419
649979248	887	25.36	384	860	8	484	4.0e-57	217	COG0591	Na+/proline symporter	493
649979249	309	38.83	6	292	4	290	1.0e-58	220	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
649979251	387	27.1	20	269	72	328	2.0e-24	107	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
649979254	1029	23.93	4	1013	8	1007	0.0e+00	466	COG0841	Multidrug efflux pump subunit AcrB	1009
649979256	548	19.84	7	373	5	327	9.0e-24	105	COG0644	Dehydrogenase (flavoprotein)	396
649979257	534	21.53	1	352	1	309	3.0e-26	113	COG0644	Dehydrogenase (flavoprotein)	396
649979258	2672	39.41	31	1102	1	1031	0.0e+00	809	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
649979259	684	40.04	1	509	11	532	1.0e-123	437	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
649979260	550	34.35	13	471	5	454	3.0e-83	302	COG2986	Histidine ammonia-lyase	498
649979261	443	30.3	33	434	4	472	2.0e-58	220	COG3119	Arylsulfatase A or related enzyme	475
649979262	344	39.47	8	343	1	333	5.0e-78	284	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
649979264	384	21.45	67	336	2	271	3.0e-08	53.3	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
649979265	312	38.31	10	307	1	304	8.0e-50	191	COG0524	Sugar or nucleoside kinase, ribokinase family	311
649979266	321	32.06	37	321	35	314	5.0e-44	171	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
649979267	507	49.7	1	500	2	500	0.0e+00	552	COG1129	ABC-type sugar transport system, ATPase component	500
649979268	318	42.95	11	313	8	311	1.0e-53	203	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
649979270	348	22.02	32	285	1	252	2.0e-09	57.2	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
649979271	618	28.78	30	465	1	467	2.0e-57	217	COG3119	Arylsulfatase A or related enzyme	475
649979272	551	27.5	26	533	1	473	3.0e-64	240	COG3119	Arylsulfatase A or related enzyme	475
649979275	549	31.37	92	539	1	422	2.0e-78	287	COG3669	Alpha-L-fucosidase	430
649979276	495	33.11	37	483	9	409	3.0e-81	296	COG0738	Fucose permease	422
649979278	487	25.58	22	366	3	434	2.0e-36	147	COG3119	Arylsulfatase A or related enzyme	475
649979279	275	31.91	25	270	8	254	3.0e-36	145	COG0584	Glycerophosphoryl diester phosphodiesterase	257
649979280	495	27.15	35	449	5	443	2.0e-51	197	COG3119	Arylsulfatase A or related enzyme	475
649979281	471	31.8	25	447	2	469	1.0e-64	240	COG3119	Arylsulfatase A or related enzyme	475
649979283	352	27.89	11	335	18	351	5.0e-31	128	COG0628	Predicted PurR-regulated permease PerM	355
649979284	1048	49.08	1	1027	2	1009	0.0e+00	968	COG0841	Multidrug efflux pump subunit AcrB	1009
649979285	496	26.47	12	417	7	365	5.0e-28	119	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649979286	218	43.69	12	217	8	210	2.0e-51	195	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
649979289	564	45.53	55	556	2	499	0.0e+00	519	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649979290	402	36.27	1	397	1	391	2.0e-84	306	COG1459	Type II secretory pathway, component PulF	397
649979291	157	25.17	19	152	9	149	3.0e-10	58.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
649979292	198	24.34	10	159	3	132	3.0e-04	38.8	COG4970	Tfp pilus assembly protein FimT	181
649979298	1315	24.08	668	1181	107	552	2.0e-45	179	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
649979301	415	25.96	5	415	1	384	2.0e-45	176	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649979302	358	38.7	27	348	3	322	2.0e-74	273	COG0598	Mg2+ and Co2+ transporter CorA	322
649979303	412	20	1	313	5	314	1.0e-15	77.9	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
649979311	280	36.62	1	280	2	282	8.0e-69	253	COG0169	Shikimate 5-dehydrogenase	283
649979313	427	23.02	36	400	3	342	1.0e-29	124	COG0673	Predicted dehydrogenase	342
649979314	1508	22.13	34	355	4	341	2.0e-15	79.1	COG0673	Predicted dehydrogenase	342
649979315	505	22.8	27	461	1	470	6.0e-39	155	COG3119	Arylsulfatase A or related enzyme	475
649979317	494	28.71	27	494	1	473	1.0e-60	228	COG3119	Arylsulfatase A or related enzyme	475
649979318	476	26.2	35	380	1	375	1.0e-36	147	COG3119	Arylsulfatase A or related enzyme	475
649979321	533	26.94	19	512	1	443	4.0e-51	196	COG3119	Arylsulfatase A or related enzyme	475
649979323	189	29.66	20	161	16	154	1.0e-09	56.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649979324	561	27.25	19	502	1	465	1.0e-52	201	COG3119	Arylsulfatase A or related enzyme	475
649979325	496	29.94	27	472	1	467	4.0e-58	219	COG3119	Arylsulfatase A or related enzyme	475
649979327	432	20.11	42	403	10	339	1.0e-30	128	COG0673	Predicted dehydrogenase	342
649979328	315	22	51	282	9	249	3.0e-16	79.5	COG1082	Sugar phosphate isomerase/epimerase	274
649979330	187	30.81	2	167	1	161	5.0e-22	97.9	COG0693	Putative intracellular protease/amidase	188
649979331	663	25.52	23	542	17	514	9.0e-67	248	COG0659	Sulfate permease or related transporter, MFS superfamily	554
649979332	496	25.1	5	459	1	485	6.0e-35	142	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
649979334	1027	28.13	219	976	127	857	1.0e-100	362	COG3002	Uncharacterized conserved protein YbcC, UPF0753/DUF2309 family	880
649979337	452	46.74	1	452	1	457	0.0e+00	503	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649979338	194	31.43	17	189	20	177	1.0e-13	70.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649979345	485	27.1	38	438	5	443	4.0e-50	192	COG3119	Arylsulfatase A or related enzyme	475
649979346	985	19.46	4	387	2	384	1.0e-07	52.7	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
649979347	757	27.27	22	421	3	447	4.0e-51	196	COG3119	Arylsulfatase A or related enzyme	475
649979348	316	27.3	10	313	7	312	2.0e-32	133	COG0657	Acetyl esterase/lipase	312
649979349	315	34.77	1	307	7	331	2.0e-73	269	COG3938	Proline racemase	341
649979350	260	27.2	6	126	2	123	1.0e-14	74	COG3293	Transposase	124
649979353	751	33.93	112	370	1	277	1.0e-40	162	COG0515	Serine/threonine protein kinase	384
649979354	212	44.55	1	202	1	202	3.0e-50	191	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
649979357	614	31.88	76	598	2	502	2.0e-93	336	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
649979359	558	37.66	58	207	2	155	2.0e-40	160	COG0437	Fe-S-cluster-containing dehydrogenase component	203
649979361	324	43.41	9	266	3	248	4.0e-81	295	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
649979362	288	46.69	1	257	1	246	1.0e-79	290	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
649979363	537	31.39	306	528	58	250	7.0e-38	152	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
649979364	498	26.42	77	423	29	335	3.0e-43	169	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
649979367	262	32.95	3	258	1	251	1.0e-36	146	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649979368	1097	37.85	558	807	99	336	1.0e-42	169	COG0642	Signal transduction histidine kinase	336
649979371	216	41.18	8	194	5	189	3.0e-43	168	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
649979373	455	51.72	50	397	8	350	2.0e-108	386	COG4962	Pilus assembly protein, ATPase of CpaF family	355
649979374	319	29.28	15	315	6	305	4.0e-34	138	COG4965	Flp pilus assembly protein TadB	309
649979375	333	25.24	7	313	7	315	4.0e-17	82.6	COG2064	Pilus assembly protein TadC	320
649979382	217	29.73	19	203	1	177	5.0e-15	74.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649979383	394	18.98	130	394	15	306	3.0e-11	63.6	COG0515	Serine/threonine protein kinase	384
649979388	417	58.37	1	406	1	404	0.0e+00	516	COG4277	Predicted DNA-binding protein with the Helix-hairpin-helix motif	404
649979389	461	33.51	267	451	9	195	5.0e-33	135	COG1573	Uracil-DNA glycosylase	202
649979391	340	30.95	37	287	7	248	2.0e-44	172	COG0300	Short-chain dehydrogenase	265
649979393	698	56.57	18	518	1	496	0.0e+00	689	COG0753	Catalase	496
649979394	468	21.96	26	444	15	380	6.0e-25	108	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649979395	286	20.87	1	214	3	223	1.0e-11	64	COG1216	Glycosyltransferase, GT2 family	305
649979397	356	23.62	1	349	1	376	1.0e-21	97.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649979398	483	23.41	28	464	18	443	6.0e-33	135	COG0534	Na+-driven multidrug efflux pump	455
649979400	123	32.2	1	115	6	123	1.0e-10	58.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
649979401	381	24.61	134	380	85	331	5.0e-16	79.1	COG0642	Signal transduction histidine kinase	336
649979402	746	28.42	36	469	1	461	1.0e-53	205	COG3119	Arylsulfatase A or related enzyme	475
649979403	485	24.05	24	455	1	475	2.0e-39	157	COG3119	Arylsulfatase A or related enzyme	475
649979404	472	28.63	21	429	1	434	7.0e-53	201	COG3119	Arylsulfatase A or related enzyme	475
649979406	503	32.59	2	481	1	480	4.0e-52	199	COG0591	Na+/proline symporter	493
649979407	177	21.53	15	142	6	147	3.0e-05	41.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
649979408	422	36.18	1	412	19	447	4.0e-111	395	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
649979411	178	32.82	16	146	1	125	2.0e-10	59.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
649979412	637	39.76	43	628	2	565	3.0e-127	449	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
649979413	487	28.36	26	464	1	461	7.0e-58	218	COG3119	Arylsulfatase A or related enzyme	475
649979414	595	27.76	124	577	2	469	1.0e-57	218	COG3119	Arylsulfatase A or related enzyme	475
649979428	389	20.81	105	307	31	240	7.0e-04	38.7	COG4974	Site-specific recombinase XerD	300
649979430	215	33.7	17	196	1	181	4.0e-28	117	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649979434	205	51.23	44	205	3	162	2.0e-61	228	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
649979439	366	25.18	85	352	21	284	2.0e-28	120	COG2813	16S rRNA G1207 methylase RsmC	300
649979440	149	60.69	1	145	1	145	2.0e-56	211	COG1490	D-Tyr-tRNAtyr deacylase	145
649979442	982	28.13	74	448	1	383	2.0e-44	174	COG0515	Serine/threonine protein kinase	384
649979443	360	24.92	41	360	78	387	2.0e-24	106	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649979444	426	31.76	9	385	11	385	4.0e-63	235	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
649979447	763	21.84	390	573	69	254	2.0e-08	55	COG5426	Uncharacterized membrane protein	254
649979449	250	27.72	8	106	4	104	6.0e-17	81.2	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
649979449	250	53.12	157	250	16	111	7.0e-26	111	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
649979450	442	34.83	17	437	3	410	3.0e-87	316	COG0719	Fe-S cluster assembly scaffold protein SufB	412
649979451	471	46.45	39	469	1	412	2.0e-127	449	COG0719	Fe-S cluster assembly scaffold protein SufB	412
649979452	270	56.42	3	258	2	251	4.0e-94	337	COG0396	Fe-S cluster assembly ATPase SufC	251
649979453	218	25.49	3	203	7	210	1.0e-22	99	COG2345	Predicted transcriptional regulator, ArsR family	218
649979454	539	36.38	1	459	2	429	5.0e-85	309	COG0733	Na+-dependent transporter, SNF family	439
649979457	1071	30.6	16	1036	1	1006	0.0e+00	762	COG0841	Multidrug efflux pump subunit AcrB	1009
649979459	414	27.15	43	410	12	370	6.0e-24	105	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649979460	316	20.38	65	313	19	237	1.0e-08	54.2	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
649979462	473	37.55	12	461	1	451	4.0e-98	351	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
649979463	504	36.91	32	490	11	474	8.0e-102	364	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
649979464	262	23.68	22	261	18	281	7.0e-20	91.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649979465	344	23.8	17	342	16	334	6.0e-20	92.2	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
649979468	613	56.87	8	607	5	620	0.0e+00	884	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
649979470	167	31.31	53	150	29	126	5.0e-08	50.7	COG0526	Thiol-disulfide isomerase or thioredoxin	127
649979472	785	22.38	21	756	14	721	3.0e-63	237	COG1033	Predicted exporter protein, RND superfamily	727
649979473	96	52.5	5	84	1	80	8.0e-25	104	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
649979474	345	29.91	8	345	1	329	2.0e-56	213	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
649979475	322	36	3	302	51	342	4.0e-58	218	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
649979476	248	31.45	1	244	1	237	2.0e-43	169	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
649979477	260	27.2	6	126	2	123	1.0e-14	74	COG3293	Transposase	124
649979479	257	16.99	5	256	3	253	5.0e-10	58.6	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649979481	486	26	20	429	1	455	9.0e-42	164	COG3119	Arylsulfatase A or related enzyme	475
649979483	333	40.75	13	329	8	311	3.0e-55	209	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
649979485	247	38.86	53	227	11	183	2.0e-39	155	COG1386	Chromosome segregation and condensation protein ScpB	184
649979486	197	55.38	1	195	2	195	1.0e-73	269	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
649979494	243	21.26	64	223	19	192	1.0e-09	56.8	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
649979497	113	34.38	15	110	7	97	2.0e-14	71.4	COG0023	Translation initiation factor 1 (eIF-1/SUI1)	104
649979499	183	27.65	18	179	2	171	9.0e-25	106	COG3880	Protein-arginine kinase activator protein McsA	176
649979500	188	42.16	3	184	2	178	3.0e-30	124	COG1437	Adenylate cyclase class IV, CYTH domain (includes archaeal enzymes of unknown function)	178
649979501	111	30.21	2	97	1	94	2.0e-17	81.2	COG3536	Uncharacterized conserved protein, DUF971 family	120
649979505	368	29.22	1	315	19	313	3.0e-33	136	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
649979506	534	26.94	21	508	1	475	5.0e-62	232	COG3119	Arylsulfatase A or related enzyme	475
649979509	558	33.33	282	555	90	363	1.0e-43	171	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
649979510	569	19	202	569	58	423	3.0e-34	140	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
649979511	650	38.98	326	502	4	177	2.0e-42	167	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649979513	162	28.19	16	161	6	151	3.0e-17	81.5	COG1406	Chemotaxis protein CheX, a CheY~P-specific phosphatase	153
649979514	231	27.75	22	230	2	210	4.0e-28	118	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649979516	278	24.72	1	268	9	269	1.0e-13	70.7	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
649979520	246	40.32	1	243	5	249	1.0e-51	196	COG0631	Serine/threonine protein phosphatase PrpC	262
649979521	240	28.96	7	223	10	223	6.0e-28	117	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
649979526	646	39.35	5	643	2	637	0.0e+00	538	COG0323	DNA mismatch repair ATPase MutL	638
649979527	332	32.75	20	243	20	244	1.0e-32	133	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
649979528	514	43.05	293	514	1	222	2.0e-40	160	COG1418	HD superfamily phosphodieaserase, includes HD domain of RNase Y	222
649979529	498	47.49	21	493	1	460	0.0e+00	498	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
649979531	391	39.03	1	389	18	408	1.0e-98	353	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
649979532	474	39.04	28	462	5	433	7.0e-121	427	COG0621	tRNA A37 methylthiotransferase MiaB	437
649979533	208	32.81	1	188	7	192	1.0e-18	86.6	COG0558	Phosphatidylglycerophosphate synthase	192
649979534	195	30.3	29	187	6	170	1.0e-17	83.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
649979536	659	31.99	1	618	1	519	3.0e-105	376	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
649979537	382	27.59	7	376	2	378	8.0e-35	141	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649979539	389	40.47	5	387	2	350	3.0e-83	302	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
649979540	379	55.78	67	359	1	294	2.0e-109	389	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
649979541	369	33.44	1	313	4	314	4.0e-61	228	COG4260	Membrane protease subunit, stomatin/prohibitin family, contains C-terminal Zn-ribbon domain	345
649979542	452	34.98	10	448	7	421	5.0e-76	278	COG2379	Glycerate-2-kinase	422
649979544	137	21.9	29	133	18	122	5.0e-03	33.6	COG0818	Diacylglycerol kinase	123
649979547	136	45.9	3	124	2	123	1.0e-35	142	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
649979548	238	41.36	38	227	21	210	1.0e-49	189	COG1136	ABC-type lipoprotein export system, ATPase component	226
649979549	294	35.69	11	279	17	274	2.0e-30	126	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
649979550	286	43.63	24	279	69	327	6.0e-61	227	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
649979552	118	36.61	3	114	2	113	6.0e-15	73.1	COG1734	RNA polymerase-binding transcription factor DksA	120
649979553	527	25.76	42	400	1	424	1.0e-39	157	COG3119	Arylsulfatase A or related enzyme	475
649979555	480	28.54	31	460	5	446	3.0e-51	196	COG3119	Arylsulfatase A or related enzyme	475
649979556	880	48.03	9	610	1	570	0.0e+00	608	COG0550	DNA topoisomerase IA	570
649979562	462	19.84	1	457	2	472	4.0e-39	156	COG1233	Phytoene dehydrogenase-related protein	487
649979563	83	28.95	1	76	1	75	6.0e-06	42.6	COG0236	Acyl carrier protein	80
649979564	443	38.65	37	442	4	412	3.0e-85	309	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
649979565	112	32.26	33	91	1	62	1.0e-04	38.3	COG1918	Fe2+ transport system protein FeoA	75
649979566	77	33.78	4	77	2	75	8.0e-11	58.7	COG1918	Fe2+ transport system protein FeoA	75
649979567	748	40.05	25	748	6	653	0.0e+00	615	COG0370	Fe2+ transport system protein B	653
649979569	370	32.9	2	366	1	385	2.0e-78	286	COG2309	Leucyl aminopeptidase (aminopeptidase T)	385
649979570	525	39.61	8	515	7	491	3.0e-108	386	COG0443	Molecular chaperone DnaK (HSP70)	579
649979573	686	40.2	13	684	19	691	0.0e+00	561	COG1523	Pullulanase/glycogen debranching enzyme	697
649979575	392	20.25	1	391	1	363	2.0e-28	120	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
649979578	255	38.58	8	252	2	249	6.0e-39	154	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649979580	469	47.25	22	455	1	434	7.0e-123	434	COG0305	Replicative DNA helicase	435
649979581	169	41.22	19	166	1	148	2.0e-31	128	COG0359	Ribosomal protein L9	148
649979582	175	38.98	2	175	1	167	3.0e-31	127	COG0629	Single-stranded DNA-binding protein	167
649979583	137	25.88	1	85	6	90	1.0e-09	55.6	COG0360	Ribosomal protein S6	112
649979584	192	50	1	187	2	189	3.0e-68	251	COG0193	Peptidyl-tRNA hydrolase	190
649979585	211	29.67	6	94	3	93	1.0e-11	63.4	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
649979588	957	21.99	27	266	2	230	6.0e-19	90.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649979592	338	48.65	5	330	4	333	2.0e-102	365	COG0136	Aspartate-semialdehyde dehydrogenase	334
649979594	277	29.06	13	243	9	236	7.0e-25	107	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
649979595	449	20.89	4	449	7	405	1.0e-14	74.5	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649979596	224	42.25	3	212	2	213	2.0e-60	225	COG1136	ABC-type lipoprotein export system, ATPase component	226
649979597	502	45.09	25	502	2	461	0.0e+00	465	COG0415	Deoxyribodipyrimidine photolyase	461
649979598	178	46.84	1	158	3	160	9.0e-43	166	COG0440	Acetolactate synthase, small subunit	163
649979599	334	64.26	1	333	1	333	0.0e+00	505	COG0059	Ketol-acid reductoisomerase	338
649979600	248	26.76	40	248	2	211	4.0e-22	98.5	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649979601	212	36.27	2	194	1	193	7.0e-44	170	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
649979603	661	20.36	33	187	3	155	2.0e-06	47.9	COG1225	Peroxiredoxin	157
649979604	374	24.4	40	374	79	455	9.0e-26	111	COG0277	FAD/FMN-containing dehydrogenase	459
649979605	560	48.24	1	559	5	571	0.0e+00	698	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
649979606	233	28.57	83	231	3	152	3.0e-16	78.9	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
649979607	307	19.06	42	305	4	273	9.0e-19	88	COG1082	Sugar phosphate isomerase/epimerase	274
649979608	333	50.45	1	328	2	334	1.0e-119	423	COG0536	GTPase involved in cell partioning and DNA repair	369
649979611	207	23.68	4	182	15	190	2.0e-10	59.2	COG2457	Uncharacterized protein	199
649979612	344	27.96	13	334	1	311	3.0e-32	132	COG1907	Predicted archaeal sugar kinase	312
649979613	502	25.71	110	486	116	493	3.0e-43	169	COG0464	AAA+-type ATPase, SpoVK/Ycf46/Vps4 family	494
649979614	496	35.56	214	490	2	280	6.0e-67	248	COG0169	Shikimate 5-dehydrogenase	283
649979615	181	42.13	1	178	3	172	2.0e-40	158	COG0703	Shikimate kinase	172
649979617	202	53.77	1	199	3	199	4.0e-77	280	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
649979618	247	48.99	1	247	1	240	5.0e-75	274	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
649979619	156	25.83	28	144	11	130	9.0e-14	69.6	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
649979621	117	22.81	4	117	2	114	9.0e-12	62.3	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
649979624	302	30	71	294	24	252	8.0e-31	127	COG3622	Hydroxypyruvate isomerase	260
649979625	307	33.1	9	292	2	278	8.0e-39	154	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
649979628	305	31.07	22	298	4	283	6.0e-41	161	COG1562	Phytoene/squalene synthetase	288
649979631	397	24.94	1	392	8	382	8.0e-28	118	COG0006	Xaa-Pro aminopeptidase	384
649979632	268	47.76	5	268	3	266	3.0e-69	255	COG0289	Dihydrodipicolinate reductase	266
649979634	476	51.72	1	474	2	475	0.0e+00	470	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
649979639	376	42.2	3	342	2	337	7.0e-75	274	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
649979641	457	49.28	43	457	14	422	2.0e-124	439	COG0141	Histidinol dehydrogenase	425
649979642	471	30.99	87	468	73	429	1.0e-59	224	COG0166	Glucose-6-phosphate isomerase	446
649979643	925	49.83	50	919	5	841	0.0e+00	935	COG0249	DNA mismatch repair ATPase MutS	843
649979646	177	32.41	3	145	2	139	7.0e-21	93.7	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
649979647	351	40.41	9	348	2	342	1.0e-79	290	COG2008	Threonine aldolase	342
649979649	440	21.43	41	413	3	339	9.0e-27	114	COG0673	Predicted dehydrogenase	342
649979650	1203	28.22	14	1133	24	933	0.0e+00	648	COG0060	Isoleucyl-tRNA synthetase	933
649979651	496	50	125	311	1	182	5.0e-42	165	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
649979652	964	51.87	464	964	3	509	0.0e+00	567	COG0532	Translation initiation factor IF-2, a GTPase	509
649979653	150	32.48	1	116	2	118	6.0e-21	93.3	COG0858	Ribosome-binding factor A	118
649979658	232	19.74	1	232	2	234	1.0e-12	67.2	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
649979660	469	28.92	9	414	20	419	3.0e-66	246	COG4284	UDP-N-acetylglucosamine pyrophosphorylase	472
649979662	320	28.29	1	319	2	350	5.0e-41	161	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
649979664	501	22.48	1	475	6	465	3.0e-17	83.6	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
649979665	399	20.22	10	361	15	346	1.0e-14	74.6	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
649979666	386	31.62	41	386	15	381	2.0e-43	170	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649979667	399	26.2	2	389	1	381	5.0e-35	142	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649979668	456	21.54	119	438	69	377	1.0e-12	68.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649979671	595	40.58	1	402	1	447	3.0e-104	372	COG0527	Aspartokinase	447
649979675	312	30.77	5	297	2	300	1.0e-40	160	COG1597	Diacylglycerol kinase family enzyme	301
649979677	192	37.5	24	191	1	156	5.0e-38	150	COG1225	Peroxiredoxin	157
649979680	102	33.33	6	101	6	100	3.0e-06	43.3	COG4541	Uncharacterized membrane protein	100
649979681	289	28.07	62	286	6	232	7.0e-24	104	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
649979682	149	49.66	1	147	2	146	6.0e-43	166	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
649979683	184	31.61	17	171	25	178	9.0e-12	63.6	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
649979684	1184	59.01	36	1184	2	1148	0.0e+00	1660	COG1038	Pyruvate carboxylase	1149
649979691	747	38.41	15	744	10	739	0.0e+00	555	COG4251	Bacteriophytochrome (light-regulated signal transduction histidine kinase)	750
649979692	208	26.6	2	201	10	194	2.0e-15	75.8	COG3230	Heme oxygenase	196
649979693	602	42.59	1	500	1	527	0.0e+00	476	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
649979694	432	27.47	119	386	73	343	1.0e-26	114	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
649979695	912	25.99	8	906	1	737	0.0e+00	542	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
649979696	323	45.54	22	319	20	318	1.0e-73	270	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
649979697	467	29	225	466	72	310	1.0e-25	111	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649979698	502	37.37	10	281	12	300	1.0e-61	230	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
649979699	259	41.63	4	247	1	245	1.0e-70	260	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
649979700	99	47.87	4	97	3	96	6.0e-22	95.7	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
649979702	112	35.38	1	65	1	65	3.0e-10	56.8	COG1551	sRNA-binding carbon storage regulator CsrA	73
649979710	432	23.47	55	246	14	203	1.0e-07	51.5	COG0811	Biopolymer transport protein ExbB/TolQ	216
649979711	600	23.89	12	597	8	615	1.0e-51	198	COG1297	Uncharacterized membrane protein, oligopeptide transporter (OPT) family	624
649979712	363	40.32	1	358	2	357	8.0e-90	324	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
649979713	342	37.79	7	341	1	325	1.0e-61	230	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
649979716	282	33.05	50	281	57	282	1.0e-37	150	COG3220	Uncharacterized conserved protein, UPF0276 family	282
649979718	154	39.19	7	148	8	148	1.0e-28	118	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
649979720	346	22.68	4	329	18	424	4.0e-38	152	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
649979721	546	32.07	149	527	61	442	1.0e-57	217	COG1793	ATP-dependent DNA ligase	444
649979722	844	31.04	31	844	9	803	0.0e+00	515	COG1201	Lhr-like helicase	814
649979723	235	26.42	21	209	5	190	2.0e-17	82.7	COG1407	Metallophosphoesterase superfamily enzyme	235
649979724	345	39.11	1	330	15	358	8.0e-77	280	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
649979725	1273	39.12	12	407	1	400	6.0e-123	436	COG0004	Ammonia channel protein AmtB	409
649979727	250	44.44	20	243	2	226	7.0e-71	260	COG1136	ABC-type lipoprotein export system, ATPase component	226
649979729	207	21.43	2	183	10	187	5.0e-07	48.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649979730	1181	20.81	319	1168	164	983	3.0e-34	141	COG4717	Uncharacterized protein YhaN	984
649979731	418	22.38	3	385	2	388	5.0e-30	125	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
649979733	474	17.63	83	459	45	364	4.0e-09	56.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649979734	1061	38.97	1	1043	1	1021	0.0e+00	931	COG3696	Cu/Ag efflux pump CusA	1027
649979740	430	22.02	56	417	3	342	1.0e-29	124	COG0673	Predicted dehydrogenase	342
649979741	146	34.23	7	144	6	154	2.0e-13	68.5	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649979742	478	24.07	139	461	88	461	4.0e-36	146	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649979743	283	38.89	7	272	1	261	3.0e-60	225	COG0005	Purine nucleoside phosphorylase	262
649979744	147	40.74	14	146	4	137	2.0e-29	121	COG3011	Predicted thiol-disulfide oxidoreductase YuxK, DCC family	137
649979745	468	25.67	29	434	3	459	7.0e-48	185	COG3119	Arylsulfatase A or related enzyme	475
649979746	423	20.26	117	414	90	381	3.0e-08	53.4	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
649979748	168	46.98	9	156	3	139	2.0e-37	148	COG0102	Ribosomal protein L13	148
649979749	240	54.26	112	240	2	130	7.0e-42	164	COG0103	Ribosomal protein S9	130
649979750	453	40.77	10	451	12	451	7.0e-92	331	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
649979751	603	31.56	142	588	6	447	6.0e-72	265	COG5002	Signal transduction histidine kinase	459
649979752	364	27.27	3	364	10	380	1.0e-32	134	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649979753	328	32.81	1	319	2	318	3.0e-47	182	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
649979755	401	15.64	96	368	25	299	9.0e-05	41.9	COG0582	Integrase	309
649979762	707	34.44	269	696	38	479	7.0e-91	328	COG3378	Phage- or plasmid-associated DNA primase	517
649979766	259	29.19	36	236	5	210	4.0e-26	111	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649979774	231	38.35	4	209	3	201	7.0e-47	180	COG0132	Dethiobiotin synthetase	223
649979775	361	20.18	27	340	35	371	2.0e-17	83.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
649979777	218	34.27	3	210	2	178	5.0e-32	131	COG0563	Adenylate kinase or related kinase	178
649979778	480	24.56	1	211	3	227	2.0e-17	83.8	COG0710	3-dehydroquinate dehydratase	231
649979779	319	18.9	63	316	44	285	4.0e-04	39.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
649979780	264	35.12	21	254	1	233	3.0e-35	142	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
649979785	210	33.71	34	210	4	181	1.0e-21	96.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649979787	964	21.9	283	884	153	718	5.0e-58	220	COG1033	Predicted exporter protein, RND superfamily	727
649979788	122	31.52	5	92	3	93	9.0e-09	52.4	COG0234	Co-chaperonin GroES (HSP10)	96
649979792	339	19.41	31	320	10	285	1.0e-10	61	COG4974	Site-specific recombinase XerD	300
649979796	328	41.93	1	321	3	312	9.0e-68	250	COG2826	Transposase and inactivated derivatives, IS30 family	318
649979801	287	17.02	1	227	4	188	4.0e-03	35.7	COG2129	Predicted phosphoesterase, related to the Icc protein	226
649979803	327	20.56	9	241	19	257	2.0e-06	46.9	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
649979804	1103	26.8	147	1103	80	963	8.0e-126	445	COG4403	Lantibiotic modifying enzyme	963
649979814	387	24.6	128	314	5	177	7.0e-09	55.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649979821	150	25.68	2	147	12	158	2.0e-08	51.8	COG5465	Uncharacterized protein	166
649979826	514	52.43	120	405	62	347	1.0e-68	254	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649979839	1419	20.31	875	1126	8	267	9.0e-05	43.8	COG1413	HEAT repeat	335
649979841	277	36.6	48	269	23	254	8.0e-32	130	COG4242	Cyanophycinase and related exopeptidases	293
649979845	495	24.12	162	491	78	408	3.0e-32	133	COG4826	Serine protease inhibitor	410
649979853	534	20.83	64	387	16	328	1.0e-10	61.8	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649979854	325	31.19	1	107	2	110	7.0e-10	58.5	COG2165	Type II secretory pathway, pseudopilin PulG	149
649979858	732	31.3	32	546	1	465	3.0e-69	256	COG3119	Arylsulfatase A or related enzyme	475
649979859	545	33.15	26	543	1	473	6.0e-76	278	COG3119	Arylsulfatase A or related enzyme	475
649979860	364	38.78	26	364	11	308	5.0e-64	238	COG2017	Galactose mutarotase or related enzyme	308
649979861	550	45	3	541	2	526	0.0e+00	467	COG4146	Uncharacterized membrane permease YidK, sodium:solute symporter family	571
649979862	272	41.67	4	248	3	250	2.0e-43	169	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649979864	329	32.38	4	101	3	107	1.0e-09	57.4	COG2165	Type II secretory pathway, pseudopilin PulG	149
649979868	388	27.57	5	267	61	328	8.0e-32	131	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
649979875	173	28.92	1	162	9	174	9.0e-16	76.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649979877	1283	31.39	979	1269	49	314	2.0e-34	142	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649979878	508	19.66	66	356	1	282	6.0e-14	72.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649979879	391	35.15	100	389	34	310	7.0e-49	188	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
649979880	434	27.68	30	302	39	312	2.0e-30	127	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
649979881	781	26.76	60	329	22	298	1.0e-26	115	COG0657	Acetyl esterase/lipase	312
649979882	980	31.75	21	453	1	466	6.0e-60	226	COG3119	Arylsulfatase A or related enzyme	475
649979885	424	20.82	39	355	46	385	1.0e-16	81.6	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649979886	752	21.74	114	237	2	134	1.0e-07	52.2	COG1225	Peroxiredoxin	157
649979889	260	27.2	6	126	2	123	1.0e-14	73.6	COG3293	Transposase	124
649979900	495	21.56	31	435	33	461	8.0e-35	141	COG0464	AAA+-type ATPase, SpoVK/Ycf46/Vps4 family	494
649979904	690	26.67	60	224	5	164	3.0e-08	54	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
649979908	700	26.42	23	527	4	462	1.0e-45	178	COG3119	Arylsulfatase A or related enzyme	475
649979909	468	25.48	19	438	1	462	3.0e-54	206	COG3119	Arylsulfatase A or related enzyme	475
649979914	642	37.13	15	622	18	603	2.0e-128	453	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
649979916	228	25.93	1	210	1	207	2.0e-28	119	COG2102	Diphthamide synthase (EF-2-diphthine--ammonia ligase)	223
649979917	309	27.49	2	287	54	314	1.0e-30	126	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
649979919	407	34.91	222	385	12	176	8.0e-30	124	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649979922	431	30.75	8	421	7	430	2.0e-27	117	COG0531	Amino acid transporter	466
649979923	183	23.81	13	173	14	174	2.0e-18	85.8	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
649979924	359	52.57	10	338	1	326	3.0e-113	401	COG0158	Fructose-1,6-bisphosphatase	326
649979925	618	27.15	8	612	4	660	1.0e-108	387	COG0021	Transketolase	663
649979926	496	48.39	1	488	2	483	0.0e+00	564	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
649979927	309	34.25	1	289	5	292	2.0e-58	219	COG1230	Co/Zn/Cd efflux system component	296
649979928	360	40.11	12	360	2	346	3.0e-75	275	COG3569	DNA topoisomerase IB	354
649979929	171	32.87	29	170	1	138	5.0e-26	110	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
649979930	287	31.56	4	283	9	284	4.0e-47	181	COG0788	Formyltetrahydrofolate hydrolase	287
649979938	535	32.31	12	237	1	221	8.0e-26	112	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
649979941	260	27.2	6	126	2	123	1.0e-14	74	COG3293	Transposase	124
649979950	222	24.02	4	214	10	234	6.0e-18	84.3	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
649979952	78	36.54	1	51	1	52	4.0e-08	49.9	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
649979953	229	32.83	1	196	5	200	5.0e-35	141	COG0300	Short-chain dehydrogenase	265
649979954	333	32.71	223	328	15	119	4.0e-15	75.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649979955	485	27.29	13	485	1	458	3.0e-70	259	COG5361	Uncharacterized conserved protein	458
649979956	777	30.2	58	596	1	473	8.0e-72	265	COG3119	Arylsulfatase A or related enzyme	475
649979957	788	30.28	68	597	1	474	1.0e-69	258	COG3119	Arylsulfatase A or related enzyme	475
649979958	807	28.81	76	609	1	471	6.0e-78	286	COG3119	Arylsulfatase A or related enzyme	475
649979959	780	29.19	62	603	1	475	2.0e-77	284	COG3119	Arylsulfatase A or related enzyme	475
649979961	96	43.82	1	89	1	85	1.0e-16	78	COG1343	CRISPR/Cas system-associated endoribonuclease Cas2	89
649979962	344	34.71	5	343	3	327	3.0e-69	255	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
649979964	263	23.56	43	248	16	189	2.0e-20	93.2	COG1468	CRISPR/Cas system-associated exonuclease Cas4, RecB family	190
649979965	295	29.31	1	285	4	267	3.0e-35	142	COG3649	CRISPR/Cas system type I-B associated protein Csh2, Cas7 group, RAMP superfamily	283
649979971	286	24.45	7	235	1	214	4.0e-22	98.6	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
649979972	402	35.01	23	394	8	373	3.0e-70	259	COG1454	Alcohol dehydrogenase, class IV	377
649979973	439	23.84	3	392	1	466	7.0e-30	125	COG3540	Phosphodiesterase/alkaline phosphatase D	522
649979975	373	23.71	1	370	2	360	5.0e-27	115	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
649979976	324	33.33	169	324	1	156	3.0e-39	155	COG4296	Uncharacterized protein	156
649979981	448	18.8	50	443	3	361	2.0e-11	64.1	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649979982	469	30.99	21	456	1	450	6.0e-58	218	COG3119	Arylsulfatase A or related enzyme	475
649979983	292	28.19	38	287	60	302	4.0e-22	98.8	COG0657	Acetyl esterase/lipase	312
649979984	535	18.46	1	304	1	285	4.0e-04	40.2	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649979986	927	20.88	110	378	60	327	9.0e-15	76.2	COG4219	Signal transducer regulating beta-lactamase production, contains  metallopeptidase domain	337
649979987	128	27.42	1	120	2	123	1.0e-14	71.8	COG3682	Predicted transcriptional regulator	123
649979988	489	27.18	22	462	1	469	2.0e-46	180	COG3119	Arylsulfatase A or related enzyme	475
649979991	434	37.19	100	394	49	364	8.0e-62	231	COG1858	Cytochrome c peroxidase	364
649979995	329	36.83	1	326	1	324	3.0e-56	212	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
649979997	815	67.96	52	799	1	729	0.0e+00	1140	COG0376	Catalase (peroxidase I)	730
649979998	185	29.41	1	153	1	136	6.0e-24	103	COG1943	REP element-mobilizing transposase RayT	136
649979999	544	36.5	220	544	2	303	1.0e-53	204	COG0492	Thioredoxin reductase	305
649980000	391	24.81	22	279	76	331	3.0e-26	113	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
649980003	201	28.4	33	198	14	182	2.0e-18	85.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649980005	225	43.67	3	225	2	229	2.0e-48	185	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649980006	460	35.8	137	458	16	330	3.0e-44	173	COG0642	Signal transduction histidine kinase	336
649980007	655	22.11	230	636	55	443	5.0e-23	103	COG1538	Outer membrane protein TolC	457
649980009	1047	28.19	2	1041	1	1009	0.0e+00	609	COG0841	Multidrug efflux pump subunit AcrB	1009
649980010	1037	18.72	17	435	31	398	3.0e-06	48.1	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
649980011	456	23.29	34	455	1	466	8.0e-40	158	COG3119	Arylsulfatase A or related enzyme	475
649980012	261	29.25	155	260	17	122	5.0e-16	78.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649980013	1559	20.16	376	720	66	399	7.0e-12	67.7	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
649980014	316	28.93	1	298	1	313	5.0e-46	178	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649980015	341	32.29	1	338	1	348	1.0e-58	220	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
649980016	272	27.55	25	272	17	274	9.0e-28	117	COG1082	Sugar phosphate isomerase/epimerase	274
649980018	270	36.98	6	266	1	251	5.0e-39	154	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649980019	280	33.57	1	279	6	278	2.0e-57	215	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
649980021	501	25	31	489	2	473	2.0e-44	174	COG3119	Arylsulfatase A or related enzyme	475
649980027	535	24.59	32	500	1	453	6.0e-45	175	COG3119	Arylsulfatase A or related enzyme	475
649980028	536	32.14	36	460	1	443	6.0e-60	225	COG3119	Arylsulfatase A or related enzyme	475
649980029	558	26.17	61	525	1	442	1.0e-50	194	COG3119	Arylsulfatase A or related enzyme	475
649980032	495	38	17	481	1	446	3.0e-106	378	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
649980037	509	51.01	14	506	1	490	0.0e+00	543	COG0606	Predicted ATPase with chaperone activity	490
649980040	177	30.72	26	170	24	176	1.0e-18	86.8	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
649980042	229	25	40	219	6	180	2.0e-15	75.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649980045	270	31.2	6	267	1	257	2.0e-41	163	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
649980047	143	44.2	1	137	2	137	9.0e-42	162	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
649980048	373	57.72	2	369	1	357	0.0e+00	483	COG0082	Chorismate synthase	369
649980049	396	46	7	395	3	390	8.0e-110	390	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
649980050	142	50	10	140	8	138	6.0e-37	146	COG0314	Molybdopterin synthase catalytic subunit	149
649980051	81	33.33	2	81	1	84	1.0e-08	51.1	COG1977	Molybdopterin converting factor, small subunit	84
649980052	1014	31.91	26	529	9	456	7.0e-67	249	COG0277	FAD/FMN-containing dehydrogenase	459
649980053	741	44.98	19	612	1	588	0.0e+00	605	COG0514	Superfamily II DNA helicase RecQ	590
649980054	268	36.06	3	268	1	231	4.0e-61	228	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
649980057	255	22.05	5	251	1	260	4.0e-14	72.1	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649980060	418	22.94	48	416	1	378	4.0e-30	126	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649980061	381	26.61	11	373	2	380	2.0e-35	143	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649980062	358	26.33	58	352	86	381	1.0e-28	120	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649980063	676	32.9	133	670	48	564	8.0e-104	371	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
649980066	262	22.56	30	196	6	200	2.0e-10	60	COG0775	Nucleoside phosphorylase	234
649980068	96	38.16	1	76	8	81	6.0e-11	58.9	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
649980069	188	39.04	1	186	7	193	2.0e-31	128	COG0576	Molecular chaperone GrpE (heat shock protein)	193
649980070	382	48.23	5	369	3	368	4.0e-119	421	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
649980071	537	45.26	1	531	2	523	1.0e-129	456	COG0459	Chaperonin GroEL (HSP60 family)	524
649980072	95	63.83	1	94	1	94	4.0e-29	119	COG0234	Co-chaperonin GroES (HSP10)	96
649980073	569	44.51	1	532	2	521	1.0e-123	437	COG0459	Chaperonin GroEL (HSP60 family)	524
649980076	492	30.79	32	455	2	455	5.0e-54	205	COG3119	Arylsulfatase A or related enzyme	475
649980077	537	44.26	1	532	2	524	5.0e-130	458	COG0459	Chaperonin GroEL (HSP60 family)	524
649980078	100	61.96	7	98	1	92	3.0e-30	122	COG0234	Co-chaperonin GroES (HSP10)	96
649980080	197	38.02	6	193	15	205	1.0e-42	166	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
649980081	434	43.15	2	388	1	382	1.0e-100	360	COG1641	Uncharacterized conserved protein, DUF111 family	387
649980083	360	52.49	1	357	2	347	1.0e-114	406	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
649980085	401	23.08	1	374	6	393	1.0e-27	117	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
649980088	181	25.73	8	160	7	177	7.0e-12	63.9	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
649980097	329	23.31	1	325	4	311	2.0e-22	100	COG0385	Predicted Na+-dependent transporter	319
649980099	282	53.87	6	274	5	271	3.0e-99	355	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
649980101	153	29.69	11	137	10	137	1.0e-12	66.2	COG0071	Molecular chaperone IbpA, HSP20 family	146
649980102	137	33.33	23	135	31	144	6.0e-16	76.6	COG0071	Molecular chaperone IbpA, HSP20 family	146
649980104	337	57.62	11	337	5	330	0.0e+00	503	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
649980110	248	37.05	1	246	2	246	1.0e-50	193	COG1385	16S rRNA U1498 N3-methylase RsmE	246
649980111	70	49.09	10	62	1	55	4.0e-10	56.6	COG3369	Uncharacterized protein, contains Zn-finger domain of CDGSH type	78
649980113	315	54.78	1	314	1	313	4.0e-112	398	COG0462	Phosphoribosylpyrophosphate synthetase	314
649980114	239	38.94	10	233	1	223	4.0e-57	214	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
649980116	237	45.67	22	229	2	208	3.0e-70	258	COG0177	Endonuclease III	211
649980117	344	48.66	5	339	4	338	3.0e-102	365	COG0547	Anthranilate phosphoribosyltransferase	338
649980119	275	53.93	8	274	5	260	7.0e-92	330	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
649980120	66	45.45	1	66	3	68	2.0e-12	64.1	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
649980121	447	30.59	229	442	2	220	4.0e-33	136	COG0569	Trk K+ transport system, NAD-binding component	225
649980122	215	40.93	1	213	2	208	3.0e-46	178	COG0135	Phosphoribosylanthranilate isomerase	208
649980124	503	28.45	53	379	55	385	2.0e-40	160	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649980125	252	34.98	2	240	1	240	3.0e-46	178	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
649980126	584	20	276	562	12	294	3.0e-03	37.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649980129	113	39.29	2	113	1	112	2.0e-26	110	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
649980132	86	59.77	1	84	1	87	5.0e-27	112	COG0211	Ribosomal protein L27	87
649980134	449	33.93	8	445	13	459	8.0e-89	321	COG1109	Phosphomannomutase	464
649980135	1696	30.47	742	1176	57	465	2.0e-43	172	COG2319	WD40 repeat	466
649980141	179	43.03	10	174	11	175	5.0e-43	167	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
649980142	580	26.81	261	571	33	336	6.0e-30	126	COG0642	Signal transduction histidine kinase	336
649980143	413	29.1	6	349	4	354	3.0e-46	179	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
649980144	133	41.35	1	104	1	102	1.0e-23	102	COG0261	Ribosomal protein L21	103
649980145	534	40.66	3	514	2	479	4.0e-118	418	COG1530	Ribonuclease G or E	487
649980148	252	46.46	1	246	1	249	9.0e-68	250	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
649980150	458	29.82	30	420	1	443	5.0e-54	205	COG3119	Arylsulfatase A or related enzyme	475
649980153	707	23.88	9	354	14	351	4.0e-34	140	COG4972	Tfp pilus assembly protein, ATPase PilM	354
649980154	352	42.57	150	345	7	208	1.0e-47	183	COG0352	Thiamine monophosphate synthase	211
649980156	321	25.99	47	318	4	274	3.0e-27	116	COG1082	Sugar phosphate isomerase/epimerase	274
649980157	124	38.61	24	123	8	108	2.0e-16	77.7	COG0607	Rhodanese-related sulfurtransferase	110
649980158	305	19.23	36	279	5	252	8.0e-10	57.9	COG1082	Sugar phosphate isomerase/epimerase	274
649980161	187	30.91	24	133	7	116	3.0e-13	68.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
649980164	250	40.32	1	250	1	253	1.0e-59	223	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
649980165	236	39.82	7	227	1	209	8.0e-48	183	COG4869	Propanediol utilization protein	210
649980168	398	43.03	1	398	1	396	2.0e-112	399	COG0282	Acetate kinase	396
649980169	105	43.01	1	93	1	87	7.0e-16	75.3	COG4576	Carboxysome shell and ethanolamine utilization microcompartment protein CcmK/EutM	89
649980171	477	22.77	43	455	36	448	7.0e-40	158	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
649980173	84	41.67	1	84	1	83	2.0e-13	67.6	COG4576	Carboxysome shell and ethanolamine utilization microcompartment protein CcmK/EutM	89
649980175	95	26.6	1	94	1	89	3.0e-07	46.4	COG4576	Carboxysome shell and ethanolamine utilization microcompartment protein CcmK/EutM	89
649980176	301	31.58	11	216	5	213	8.0e-42	164	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
649980178	317	44.34	11	317	13	329	2.0e-69	256	COG0714	MoxR-like ATPase	329
649980182	351	49.69	27	351	2	322	2.0e-99	356	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
649980183	283	52.48	1	279	1	282	5.0e-100	357	COG0414	Panthothenate synthetase	285
649980184	362	27.68	87	351	21	281	4.0e-32	132	COG0682	Prolipoprotein diacylglyceryltransferase	287
649980185	195	38.2	4	181	1	177	2.0e-30	125	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649980188	493	27	40	493	1	472	2.0e-56	214	COG3119	Arylsulfatase A or related enzyme	475
649980189	457	20.98	64	405	15	356	1.0e-14	74.9	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649980192	684	22.09	59	219	5	160	3.0e-05	44	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
649980202	96	43.82	1	89	1	85	1.0e-16	78	COG1343	CRISPR/Cas system-associated endoribonuclease Cas2	89
649980203	344	34.71	5	343	3	327	3.0e-69	255	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
649980205	263	23.56	43	248	16	189	2.0e-20	93.2	COG1468	CRISPR/Cas system-associated exonuclease Cas4, RecB family	190
649980206	295	29.31	1	285	4	267	3.0e-35	142	COG3649	CRISPR/Cas system type I-B associated protein Csh2, Cas7 group, RAMP superfamily	283
649980210	260	28	6	126	2	123	3.0e-15	75.9	COG3293	Transposase	124
649980214	234	21.83	14	207	15	205	1.0e-12	66.9	COG0811	Biopolymer transport protein ExbB/TolQ	216
649980215	108	35.51	2	107	7	113	2.0e-14	70.8	COG4744	Uncharacterized protein	121
649980216	1382	32.19	38	1377	7	1386	0.0e+00	927	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
649980218	375	20.69	9	321	4	278	3.0e-17	83	COG0492	Thioredoxin reductase	305
649980221	238	42.79	4	215	3	216	1.0e-55	209	COG1131	ABC-type multidrug transport system, ATPase component	293
649980227	260	27.2	6	126	2	123	1.0e-14	74	COG3293	Transposase	124
649980228	721	21.79	28	424	5	395	2.0e-17	84.7	COG1668	ABC-type Na+ efflux pump, permease component	407
649980229	107	36.36	4	101	1	99	6.0e-08	49	COG0640	DNA-binding transcriptional regulator, ArsR family	110
649980230	304	28.87	18	304	4	285	7.0e-46	177	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
649980231	289	27.33	1	284	6	316	2.0e-39	156	COG0226	ABC-type phosphate transport system, periplasmic component	318
649980232	280	42.32	2	280	15	307	4.0e-51	195	COG0573	ABC-type phosphate transport system, permease component	310
649980233	299	39.64	13	285	8	286	4.0e-51	195	COG0581	ABC-type phosphate transport system, permease component	292
649980234	252	52.19	2	252	8	253	8.0e-90	323	COG1117	ABC-type phosphate transport system, ATPase component	253
649980238	153	29.05	11	153	3	145	5.0e-17	80.8	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
649980239	233	50.45	1	221	1	222	2.0e-73	268	COG1136	ABC-type lipoprotein export system, ATPase component	226
649980243	414	41.08	19	383	1	321	2.0e-88	319	COG0523	GTPase, G3E family	323
649980247	592	28.82	26	422	1	462	7.0e-59	222	COG3119	Arylsulfatase A or related enzyme	475
649980250	470	31.91	26	466	1	462	5.0e-64	238	COG3119	Arylsulfatase A or related enzyme	475
649980252	314	33.44	4	313	1	314	1.0e-57	217	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649980253	451	54.65	1	418	1	414	0.0e+00	547	COG1004	UDP-glucose 6-dehydrogenase	414
649980254	433	25.25	17	420	2	378	4.0e-23	103	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649980255	302	29.5	40	300	8	261	5.0e-37	148	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
649980256	416	42.91	3	270	2	249	8.0e-71	261	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
649980258	429	20.79	41	403	6	379	4.0e-23	102	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649980263	295	18.97	1	226	2	247	2.0e-08	53.2	COG1216	Glycosyltransferase, GT2 family	305
649980264	417	24.16	1	410	3	380	5.0e-32	132	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649980267	354	19.48	5	348	37	374	9.0e-21	94.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649980268	286	19.8	1	275	2	287	1.0e-14	74	COG1216	Glycosyltransferase, GT2 family	305
649980275	315	24.04	14	271	6	292	2.0e-17	83.6	COG1216	Glycosyltransferase, GT2 family	305
649980277	415	28.47	141	409	98	377	2.0e-31	130	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649980278	375	26.58	78	370	80	379	1.0e-28	120	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649980279	404	25.25	1	386	2	381	6.0e-34	138	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649980280	403	22.92	1	390	1	381	3.0e-35	142	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649980282	572	24.08	102	291	37	212	6.0e-04	39.5	COG4083	Exosortase/Archaeosortase	239
649980284	182	39.26	52	181	41	175	1.0e-21	96.1	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
649980286	218	18.78	12	204	16	199	2.0e-04	39.4	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
649980291	862	16.33	127	456	76	417	7.0e-09	56.7	COG3307	O-antigen ligase	424
649980292	515	27.52	1	314	3	315	1.0e-43	171	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
649980293	190	20.45	32	188	4	175	1.0e-05	43.4	COG0250	Transcription antitermination factor NusG	178
649980294	323	30.65	9	312	3	314	7.0e-45	174	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649980295	362	67.65	11	348	2	340	0.0e+00	550	COG1089	GDP-D-mannose dehydratase	345
649980296	773	30.04	532	751	30	251	6.0e-35	142	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
649980302	268	20.31	5	245	4	243	5.0e-07	48.5	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
649980303	176	44.91	10	174	7	169	2.0e-44	172	COG3656	Predicted periplasmic protein	172
649980304	218	44.81	6	217	7	213	3.0e-48	185	COG3295	Uncharacterized protein	213
649980305	335	34.92	20	332	32	320	1.0e-51	197	COG4607	ABC-type enterochelin transport system, periplasmic component	320
649980309	178	24.43	1	173	5	180	2.0e-16	78.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649980312	281	24.61	15	258	4	253	3.0e-23	102	COG1082	Sugar phosphate isomerase/epimerase	274
649980313	389	23.38	1	385	1	341	1.0e-40	161	COG0673	Predicted dehydrogenase	342
649980314	329	22.19	33	328	9	296	2.0e-11	63.7	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
649980315	310	33.05	183	300	4	121	9.0e-20	91.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649980318	283	25.17	5	283	16	293	6.0e-20	91.5	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
649980319	231	32.6	1	227	12	226	2.0e-31	129	COG1802	DNA-binding transcriptional regulator, GntR family	230
649980320	313	33.33	14	310	1	290	7.0e-60	224	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
649980321	531	23.5	10	519	4	478	8.0e-39	155	COG0591	Na+/proline symporter	493
649980322	932	27.08	467	925	1	467	2.0e-57	218	COG3119	Arylsulfatase A or related enzyme	475
649980323	1006	18.99	677	988	29	374	2.0e-24	108	COG4692	Predicted neuraminidase (sialidase)	381
649980325	216	25.99	38	210	4	180	2.0e-15	75.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649980329	266	29.02	6	259	3	253	2.0e-41	162	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
649980333	479	31.71	81	438	18	369	6.0e-42	165	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
649980335	310	22.5	27	142	7	125	6.0e-07	48.4	COG4319	Ketosteroid isomerase homolog	137
649980337	257	48.65	8	227	2	223	5.0e-73	267	COG1136	ABC-type lipoprotein export system, ATPase component	226
649980339	270	51.38	25	237	2	219	1.0e-71	263	COG1136	ABC-type lipoprotein export system, ATPase component	226
649980340	936	18.42	17	423	2	417	2.0e-13	71.7	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649980342	314	33.09	37	309	6	264	5.0e-44	171	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
649980344	332	25.85	1	142	2	148	1.0e-09	57.8	COG2165	Type II secretory pathway, pseudopilin PulG	149
649980347	301	26.52	72	292	1	230	6.0e-19	88.2	COG1802	DNA-binding transcriptional regulator, GntR family	230
649980348	428	37.4	48	413	25	371	3.0e-72	266	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
649980350	306	25.33	10	306	5	298	6.0e-34	138	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
649980351	442	19.19	9	437	27	448	7.0e-22	98.7	COG2271	Sugar phosphate permease	448
649980353	362	40.18	22	353	1	335	3.0e-64	239	COG3367	Uncharacterized conserved protein, NAD-dependent epimerase/dehydratase family	339
649980354	343	27.4	1	341	4	362	1.0e-41	164	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
649980355	281	38.49	60	276	3	238	7.0e-51	194	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
649980356	579	31.05	250	515	26	322	1.0e-29	125	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649980357	618	22.16	149	618	3	469	2.0e-31	130	COG1757	Na+/H+ antiporter NhaC	485
649980358	476	30.11	29	439	1	457	9.0e-50	191	COG3119	Arylsulfatase A or related enzyme	475
649980361	356	42.72	30	344	10	325	2.0e-86	312	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
649980362	253	47.2	1	250	9	258	3.0e-54	205	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
649980363	339	33	13	307	5	300	1.0e-44	173	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
649980364	302	54.03	38	283	4	247	9.0e-89	320	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
649980365	435	46.82	6	435	9	444	0.0e+00	487	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
649980366	330	43.04	1	312	1	310	2.0e-86	312	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649980368	272	23.42	47	251	2	205	4.0e-10	58.8	COG4285	Uncharacterized conserved protein , conains N-terminal glutamine amidotransferase (GATase1)-like domain	253
649980370	156	58.57	16	155	1	138	7.0e-47	179	COG3565	Predicted dioxygenase of extradiol dioxygenase family	138
649980372	594	40.22	38	585	6	539	0.0e+00	465	COG0405	Gamma-glutamyltranspeptidase	539
649980377	338	50.3	9	337	10	338	4.0e-123	434	COG2130	NADPH-dependent curcumin reductase CurA	340
649980378	1491	26.05	52	260	8	220	6.0e-18	87.4	COG3828	Type 1 glutamine amidotransferase (GATase1)-like domain	239
649980380	336	27.13	1	126	2	130	2.0e-09	56.6	COG2165	Type II secretory pathway, pseudopilin PulG	149
649980381	381	24.84	4	299	2	311	4.0e-33	135	COG0673	Predicted dehydrogenase	342
649980384	386	26.6	1	272	55	329	7.0e-30	125	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
649980385	329	26.47	61	326	16	260	5.0e-32	131	COG3622	Hydroxypyruvate isomerase	260
649980386	374	24.72	29	370	2	342	4.0e-35	142	COG0673	Predicted dehydrogenase	342
649980387	334	20.9	1	312	3	335	3.0e-18	86.2	COG4188	Predicted dienelactone hydrolase	365
649980388	295	40.68	71	295	3	235	6.0e-45	174	COG0412	Dienelactone hydrolase	236
649980389	513	21.68	20	285	26	310	2.0e-22	100	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
649980391	324	40.62	10	320	5	329	4.0e-63	235	COG0714	MoxR-like ATPase	329
649980393	410	23.08	26	362	2	347	2.0e-25	110	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
649980395	683	25.33	136	427	10	279	6.0e-28	119	COG0515	Serine/threonine protein kinase	384
649980396	486	20.88	39	433	45	462	5.0e-30	125	COG3540	Phosphodiesterase/alkaline phosphatase D	522
649980397	656	25.9	22	496	1	460	5.0e-51	196	COG3119	Arylsulfatase A or related enzyme	475
649980399	189	21.79	17	175	2	178	1.0e-13	69.6	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
649980400	508	26.39	58	498	58	434	1.0e-62	234	COG3303	Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit	501
649980401	494	28.72	23	431	1	443	4.0e-53	202	COG3119	Arylsulfatase A or related enzyme	475
649980405	410	52.07	1	408	3	412	8.0e-118	417	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
649980406	142	36.23	7	142	3	136	1.0e-28	118	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
649980407	181	30.23	9	136	7	134	2.0e-18	85.4	COG4319	Ketosteroid isomerase homolog	137
649980408	127	44.64	1	109	1	112	3.0e-30	123	COG3795	Uncharacterized conserved protein	123
649980409	141	41.6	1	123	1	123	5.0e-34	136	COG3795	Uncharacterized conserved protein	123
649980410	249	38.05	1	110	1	113	5.0e-20	91.5	COG3795	Uncharacterized conserved protein	123
649980411	146	34.06	6	132	2	136	1.0e-23	102	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
649980413	442	54.55	1	439	1	440	0.0e+00	526	COG3724	Succinylarginine dihydrolase	442
649980414	490	42.89	9	461	1	452	3.0e-105	375	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
649980415	342	48.22	1	336	1	335	2.0e-103	368	COG3138	Arginine/ornithine N-succinyltransferase beta subunit	336
649980416	464	30.53	35	460	12	445	2.0e-54	206	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
649980417	417	25.06	36	402	20	409	8.0e-31	128	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
649980418	494	24.77	41	381	6	419	3.0e-32	133	COG3119	Arylsulfatase A or related enzyme	475
649980419	514	22.61	1	362	15	411	3.0e-30	126	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649980421	343	44.74	11	343	7	322	1.0e-84	307	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
649980424	953	35.05	171	897	7	649	0.0e+00	558	COG0209	Ribonucleotide reductase alpha subunit	696
649980426	353	36.98	15	351	7	339	3.0e-94	338	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
649980429	245	50.42	1	239	8	230	2.0e-63	235	COG0689	Ribonuclease PH	230
649980430	565	17.69	5	409	2	371	2.0e-05	44.4	COG0738	Fucose permease	422
649980431	249	52.5	1	240	1	239	2.0e-85	309	COG0052	Ribosomal protein S2	252
649980432	277	43.57	1	277	1	276	3.0e-59	222	COG0264	Translation elongation factor EF-Ts	296
649980433	250	54.39	7	244	2	238	8.0e-78	283	COG0528	Uridylate kinase	238
649980434	186	52.97	1	185	2	186	7.0e-55	206	COG0233	Ribosome recycling factor	187
649980436	325	24.02	29	253	20	244	2.0e-20	93.5	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
649980438	223	50.25	8	209	6	207	7.0e-61	227	COG2518	Protein-L-isoaspartate O-methyltransferase	209
649980439	599	38.91	45	555	4	489	2.0e-94	340	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
649980440	1089	19.8	253	624	37	398	2.0e-05	45.8	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
649980441	582	42.86	6	571	5	568	0.0e+00	579	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
649980442	341	35.4	1	286	1	287	3.0e-61	228	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
649980444	346	55.47	63	336	13	286	9.0e-99	353	COG2876	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	286
649980445	256	53.15	1	254	1	250	7.0e-80	290	COG0149	Triosephosphate isomerase	251
649980446	187	32.31	7	70	3	66	2.0e-07	49	COG1314	Preprotein translocase subunit SecG	86
649980447	295	35.69	1	295	1	290	1.0e-61	230	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
649980448	209	47.49	20	198	6	180	2.0e-55	208	COG0194	Guanylate kinase	191
649980454	541	33.97	21	536	6	516	3.0e-79	289	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
649980456	351	49.67	47	349	6	308	3.0e-95	342	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
649980457	390	35.8	132	367	4	245	5.0e-42	165	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
649980458	468	39.13	16	465	1	457	1.0e-82	301	COG0277	FAD/FMN-containing dehydrogenase	459
649980460	116	30	24	113	4	93	2.0e-12	65	COG1359	Quinol monooxygenase YgiN	100
649980461	248	18.43	22	234	2	207	3.0e-12	65.9	COG0655	Multimeric flavodoxin WrbA	207
649980462	533	29.77	6	521	1	477	6.0e-84	305	COG2509	Uncharacterized FAD-dependent dehydrogenase	486
649980463	434	32.23	9	287	2	299	8.0e-45	174	COG0515	Serine/threonine protein kinase	384
649980465	386	49.36	7	386	5	394	0.0e+00	477	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
649980467	438	39.72	290	430	42	176	3.0e-30	126	COG2322	Uncharacterized membrane protein YozB, DUF420 family	177
649980470	184	39.33	2	177	1	175	6.0e-39	153	COG0461	Orotate phosphoribosyltransferase	201
649980472	404	44.16	11	402	4	368	3.0e-104	372	COG0263	Glutamate 5-kinase	369
649980474	505	25.25	8	492	4	465	6.0e-57	215	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
649980475	1278	37.07	32	307	2	292	2.0e-46	181	COG0515	Serine/threonine protein kinase	384
649980476	337	45.28	23	331	20	328	7.0e-70	257	COG0714	MoxR-like ATPase	329
649980479	723	22.05	18	707	6	678	2.0e-56	214	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
649980480	411	25.93	12	209	12	216	1.0e-18	87.9	COG0705	Membrane associated serine protease, rhomboid family	228
649980485	143	41.73	1	125	1	120	2.0e-26	111	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
649980486	143	37.01	1	125	1	120	2.0e-21	95.3	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
649980487	136	38.02	1	118	1	121	2.0e-21	94.6	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
649980488	137	36.13	5	119	4	121	3.0e-15	74.5	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
649980489	675	47.91	5	672	7	667	0.0e+00	774	COG0272	NAD-dependent DNA ligase	667
649980491	267	30.43	8	264	9	281	1.0e-27	116	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649980492	302	43.36	4	259	3	254	6.0e-84	304	COG1099	Predicted metal-dependent hydrolase, TIM-barrel fold	254
649980493	274	48.71	43	271	28	259	2.0e-72	265	COG3823	Glutamine cyclotransferase	262
649980494	238	33.33	26	222	14	211	5.0e-24	104	COG0811	Biopolymer transport protein ExbB/TolQ	216
649980495	141	32.26	16	139	18	134	2.0e-19	88.3	COG0848	Biopolymer transport protein ExbD	137
649980496	153	24.83	1	145	1	131	4.0e-09	54.1	COG0848	Biopolymer transport protein ExbD	137
649980497	261	44.75	6	260	2	256	3.0e-81	295	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
649980500	399	22.75	84	331	66	294	2.0e-12	67.2	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
649980501	146	35.51	3	140	2	138	5.0e-26	110	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
649980504	868	20.99	360	685	66	398	4.0e-11	63.9	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
649980507	66	29.09	9	62	10	64	4.0e-04	36.4	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
649980510	560	31.53	13	557	9	489	1.0e-98	354	COG0286	Type I restriction-modification system, DNA methylase subunit	489
649980511	436	20.6	104	430	86	390	6.0e-29	122	COG0732	Restriction endonuclease S subunit	391
649980513	1030	33.23	43	1001	35	961	0.0e+00	588	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
649980520	436	20.71	59	360	2	273	3.0e-09	56.8	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649980521	193	77.24	71	193	7	129	3.0e-54	205	COG0048	Ribosomal protein S12	129
649980522	157	44.9	4	150	3	148	9.0e-42	162	COG0049	Ribosomal protein S7	148
649980525	677	30.5	14	260	1	279	9.0e-36	145	COG0515	Serine/threonine protein kinase	384
649980529	307	26.39	16	297	6	253	1.0e-10	61.2	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
649980531	340	31.67	13	338	5	329	1.0e-46	180	COG1085	Galactose-1-phosphate uridylyltransferase	338
649980533	795	31.6	564	785	31	260	2.0e-40	161	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
649980534	356	39.69	30	340	1	313	9.0e-60	224	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649980536	459	24.16	123	412	48	315	5.0e-14	72.7	COG4299	Predicted acyltransferase	371
649980542	164	51.83	1	164	1	164	1.0e-34	139	COG3685	Ferritin-like metal-binding protein YciE	167
649980543	454	38.73	1	454	14	468	5.0e-120	424	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
649980545	377	21.9	26	360	3	314	7.0e-29	121	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649980549	274	44.69	8	273	1	265	3.0e-44	172	COG0428	Zinc transporter ZupT	266
649980551	69	50.72	1	69	1	69	3.0e-16	76.9	COG3360	Flavin-binding protein dodecin	71
649980552	108	25.69	1	108	3	108	2.0e-08	51.1	COG0607	Rhodanese-related sulfurtransferase	110
649980553	228	40.29	17	222	2	205	2.0e-43	168	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649980556	354	20.63	5	319	2	292	6.0e-20	91.8	COG0530	Ca2+/Na+ antiporter	320
649980558	382	51.06	1	375	1	374	0.0e+00	488	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
649980561	630	54.85	1	611	18	628	0.0e+00	739	COG0296	1,4-alpha-glucan branching enzyme	628
649980562	433	35	32	431	87	458	8.0e-71	261	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
649980564	128	48.33	2	121	21	140	3.0e-34	137	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
649980566	555	26.69	316	551	13	337	2.0e-26	113	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
649980568	598	22.61	287	515	13	235	9.0e-16	78.8	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
649980569	156	57.42	1	154	1	155	8.0e-49	186	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
649980570	531	64.89	213	531	1	315	0.0e+00	530	COG0519	GMP synthase, PP-ATPase domain/subunit	315
649980571	252	32.04	41	216	9	185	3.0e-09	55.7	COG0666	Ankyrin repeat	235
649980572	406	52.09	1	405	2	402	0.0e+00	497	COG0137	Argininosuccinate synthase	403
649980573	739	29.48	164	736	46	594	1.0e-85	311	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
649980574	314	23.55	66	312	25	274	1.0e-12	67.2	COG1082	Sugar phosphate isomerase/epimerase	274
649980575	344	27.38	8	329	5	309	1.0e-34	140	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
649980577	711	54.9	4	695	3	690	0.0e+00	850	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
649980578	89	56.18	1	89	1	89	2.0e-23	101	COG0184	Ribosomal protein S15P/S13E	89
649980582	146	30.71	18	143	1	120	1.0e-12	65.5	COG3293	Transposase	124
649980584	530	35.63	7	495	4	454	4.0e-110	392	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
649980585	304	37.54	1	292	1	290	6.0e-61	227	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
649980586	278	36.51	38	277	28	255	3.0e-41	162	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
649980588	494	20.42	146	412	35	315	3.0e-15	77.2	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649980592	265	19.2	54	262	49	272	2.0e-09	56.4	COG1082	Sugar phosphate isomerase/epimerase	274
649980594	199	43.24	34	175	2	143	1.0e-23	103	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
649980596	519	31.36	17	183	1	163	2.0e-25	111	COG0597	Lipoprotein signal peptidase	167
649980598	602	27.2	9	492	11	441	7.0e-40	159	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
649980599	325	49.36	7	317	2	313	7.0e-95	340	COG0462	Phosphoribosylpyrophosphate synthetase	314
649980601	260	27.2	6	126	2	123	1.0e-14	73.6	COG3293	Transposase	124
649980603	203	62.44	1	203	2	202	5.0e-83	300	COG0605	Superoxide dismutase	204
649980604	143	28.03	1	130	1	124	2.0e-11	61.8	COG0848	Biopolymer transport protein ExbD	137
649980605	245	32.85	106	242	7	133	6.0e-19	88	COG0848	Biopolymer transport protein ExbD	137
649980611	336	18.98	15	318	8	407	7.0e-06	45.4	COG5368	Uncharacterized protein	451
649980620	507	22.45	51	475	3	334	2.0e-32	133	COG0673	Predicted dehydrogenase	342
649980621	432	23.51	6	399	7	382	6.0e-11	62.5	COG2814	Predicted arabinose efflux permease, MFS family	394
649980622	368	41.94	28	267	1	248	3.0e-64	239	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
649980625	896	61.4	13	896	9	887	0.0e+00	1234	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
649980626	444	41.31	1	443	1	404	2.0e-96	346	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
649980627	479	49.56	11	464	2	454	0.0e+00	476	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
649980628	286	27.56	1	281	1	252	2.0e-31	130	COG0543	NAD(P)H-flavin reductase	252
649980630	136	41.94	1	93	2	92	4.0e-21	93.7	COG0776	Bacterial nucleoid DNA-binding protein	94
649980632	345	38.49	31	325	2	305	1.0e-70	260	COG0167	Dihydroorotate dehydrogenase	310
649980633	322	45.45	3	301	8	313	2.0e-90	326	COG0180	Tryptophanyl-tRNA synthetase	314
649980637	584	46.59	1	337	3	326	1.0e-81	297	COG1796	DNA polymerase/3'-5' exonuclease PolX	326
649980640	302	25	1	119	1	116	4.0e-09	55.8	COG2165	Type II secretory pathway, pseudopilin PulG	149
649980641	212	39.61	4	210	3	200	3.0e-37	148	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
649980642	230	50.22	4	229	2	219	2.0e-72	265	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
649980644	387	39.36	6	381	6	349	4.0e-81	295	COG3869	Protein-arginine kinase	352
649980645	310	38.56	50	196	1	147	1.0e-26	113	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
649980646	181	22.58	15	164	16	164	8.0e-08	50.4	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
649980647	579	37.08	259	577	14	313	1.0e-59	224	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
649980648	349	25.62	20	327	11	314	7.0e-27	114	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
649980649	329	24.42	33	322	24	316	2.0e-35	143	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
649980651	457	49.59	93	454	3	365	2.0e-127	449	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
649980652	445	21.08	64	432	52	394	5.0e-12	66	COG2814	Predicted arabinose efflux permease, MFS family	394
649980653	417	51.05	33	414	14	365	1.0e-122	433	COG2021	Homoserine acetyltransferase	368
649980655	238	21.4	37	234	1	214	1.0e-04	40.3	COG2755	Lysophospholipase L1 or related esterase	216
649980656	349	54.63	13	344	9	341	2.0e-102	366	COG1077	Actin-like ATPase involved in cell morphogenesis	342
649980657	312	22.32	70	290	69	268	6.0e-15	75	COG1792	Cell shape-determining protein MreC	284
649980663	361	43.82	1	340	2	338	2.0e-84	306	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
649980664	304	35.79	18	296	2	279	1.0e-57	217	COG3494	Uncharacterized conserved protein, DUF1009 family	279
649980666	879	23.94	358	841	117	549	2.0e-42	168	COG4232	Thiol:disulfide interchange protein	569
649980667	161	53.85	6	161	1	156	8.0e-54	202	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
649980668	167	44.08	8	159	1	150	2.0e-35	142	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
649980670	425	27.86	5	129	9	148	5.0e-04	39.3	COG4549	Uncharacterized protein YcnI	178
649980672	141	31.93	24	139	18	135	6.0e-19	86.4	COG1832	Predicted CoA-binding protein	140
649980673	407	38.8	8	390	12	388	6.0e-77	281	COG4398	Small ligand-binding sensory domain FIST	389
649980674	743	21.07	10	287	2	277	2.0e-16	81.7	COG1344	Flagellin and related hook-associated protein FlgL	360
649980675	565	28.27	1	565	1	550	1.0e-60	227	COG1256	Flagellar hook-associated protein FlgK	552
649980678	366	30.33	1	361	1	360	2.0e-44	173	COG1706	Flagellar basal body P-ring protein FlgI	365
649980679	293	25.87	100	290	34	230	4.0e-19	88.8	COG2063	Flagellar basal body L-ring protein FlgH	230
649980680	447	24.52	125	329	20	219	3.0e-13	70	COG1261	Flagella basal body P-ring formation protein FlgA	220
649980681	267	47.21	3	266	2	265	2.0e-65	242	COG4786	Flagellar basal body rod protein FlgG	265
649980682	256	39.85	1	254	1	265	8.0e-53	200	COG4786	Flagellar basal body rod protein FlgG	265
649980696	306	26.24	5	145	7	140	2.0e-10	59.7	COG2165	Type II secretory pathway, pseudopilin PulG	149
649980704	226	19.39	71	222	49	211	2.0e-08	52.6	COG2755	Lysophospholipase L1 or related esterase	216
649980706	393	40.84	4	376	3	381	1.0e-103	370	COG0116	23S rRNA G2445 N2-methylase RlmL	381
649980707	570	18.13	8	485	1	428	4.0e-16	79.8	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
649980715	203	60.71	7	202	1	196	4.0e-84	304	COG0529	Adenylylsulfate kinase or related kinase	197
649980716	383	45.62	7	381	4	380	1.0e-113	403	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
649980717	346	34.59	55	341	16	289	8.0e-55	207	COG1398	Fatty-acid desaturase	289
649980720	621	42.52	14	304	2	294	6.0e-85	308	COG1054	Predicted sulfurtransferase	308
649980721	463	47.46	12	460	3	444	0.0e+00	504	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
649980724	253	35.56	18	253	2	240	5.0e-40	157	COG2186	DNA-binding transcriptional regulator, FadR family	241
649980725	153	25.74	13	148	2	118	1.0e-12	65.8	COG4911	Uncharacterized protein	123
649980729	460	19.18	46	424	6	336	1.0e-25	111	COG0673	Predicted dehydrogenase	342
649980730	181	44.51	9	181	11	181	1.0e-46	179	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
649980731	623	29.58	287	595	31	319	9.0e-38	152	COG0142	Geranylgeranyl pyrophosphate synthase	322
649980733	281	45	1	278	1	272	6.0e-89	320	COG0253	Diaminopimelate epimerase	272
649980734	374	36.18	24	372	3	346	1.0e-75	277	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
649980735	629	27.74	285	607	2	306	4.0e-31	130	COG0668	Small-conductance mechanosensitive channel	316
649980737	367	38.33	27	367	2	316	4.0e-48	185	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
649980739	281	31.25	19	223	15	221	9.0e-27	114	COG2218	Formylmethanofuran dehydrogenase subunit C	264
649980740	563	25.7	1	560	4	534	1.0e-62	234	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
649980741	332	23.46	1	327	1	308	2.0e-37	149	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649980742	474	31.2	19	451	1	475	4.0e-61	229	COG3119	Arylsulfatase A or related enzyme	475
649980744	335	45.56	1	331	1	324	3.0e-96	345	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
649980746	495	52.42	1	452	1	449	0.0e+00	525	COG0541	Signal recognition particle GTPase	451
649980747	476	34.3	10	454	1	438	4.0e-102	365	COG0015	Adenylosuccinate lyase	438
649980749	411	34.46	59	399	8	339	3.0e-51	196	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649980750	368	18.5	89	288	51	246	2.0e-08	53.5	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
649980752	640	21.87	29	640	1	662	2.0e-34	141	COG0021	Transketolase	663
649980754	308	34.2	1	305	4	293	2.0e-65	242	COG1131	ABC-type multidrug transport system, ATPase component	293
649980755	263	45.59	1	259	2	262	3.0e-72	265	COG0300	Short-chain dehydrogenase	265
649980758	336	26.92	6	313	3	277	2.0e-28	120	COG1821	Predicted ATP-dependent carboligase, ATP-grasp superfamily	307
649980759	344	34.42	11	344	6	330	5.0e-57	214	COG1548	Uncharacterized protein, hydantoinase/oxoprolinase family	330
649980761	1081	27.2	785	1021	10	191	3.0e-38	154	COG0437	Fe-S-cluster-containing dehydrogenase component	203
649980762	474	21.33	55	461	19	399	1.0e-16	81.5	COG5557	Ni/Fe-hydrogenase 2 integral membrane subunit HybB	401
649980763	451	18.25	313	447	31	146	2.0e-05	44.6	COG2010	Cytochrome c, mono- and diheme variants	150
649980767	302	25.45	54	214	42	196	3.0e-17	82.8	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
649980768	322	30.66	6	212	19	219	5.0e-42	165	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
649980769	570	47.49	25	536	6	520	0.0e+00	486	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
649980771	118	21.21	1	97	1	98	5.0e-03	33.3	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
649980772	194	21.51	12	194	26	207	3.0e-13	68.8	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
649980776	166	31.03	1	142	19	162	1.0e-17	83.1	COG4067	Uncharacterized conserved protein	162
649980777	648	28.66	19	331	20	342	2.0e-34	141	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649980778	268	34.78	1	265	1	268	1.0e-46	180	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
649980781	264	44.23	7	261	1	260	3.0e-64	238	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
649980782	322	40.25	3	321	2	321	6.0e-87	314	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
649980783	188	29.41	1	118	1	118	5.0e-07	47.9	COG4960	Flp pilus assembly protein, protease CpaA	168
649980785	349	27.93	9	215	7	225	3.0e-17	82.7	COG3745	Flp pilus assembly protein CpaB	276
649980787	450	51	48	398	8	353	3.0e-106	378	COG4962	Pilus assembly protein, ATPase of CpaF family	355
649980788	286	27.89	31	281	57	306	1.0e-36	146	COG4965	Flp pilus assembly protein TadB	309
649980789	461	26.29	209	438	85	315	8.0e-20	91.8	COG2064	Pilus assembly protein TadC	320
649980790	424	48.29	12	216	2	203	1.0e-68	254	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
649980791	194	28.8	10	192	3	173	2.0e-12	65.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649980796	689	62.8	1	660	2	663	0.0e+00	1017	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
649980797	351	21.82	22	349	30	341	3.0e-18	86.1	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649980798	606	34.11	60	352	54	346	1.0e-45	178	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649980806	348	40.6	5	330	2	326	1.0e-65	243	COG0714	MoxR-like ATPase	329
649980807	266	33.47	16	262	4	212	1.0e-26	113	COG3132	Uncharacterized conserved protein YceH, UPF0502 family	215
649980808	120	33.02	1	104	1	105	1.0e-10	58.3	COG1544	Ribosome-associated translation inhibitor RaiA	110
649980809	156	38.06	2	154	1	152	7.0e-24	103	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
649980810	104	34.57	17	97	5	85	5.0e-16	76	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
649980811	165	31.86	40	152	13	125	2.0e-15	75.4	COG4270	Uncharacterized membrane protein	131
649980812	490	35.38	3	490	1	443	1.0e-95	343	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
649980813	203	45.41	8	203	3	198	3.0e-62	231	COG0353	Recombinational DNA repair protein RecR	198
649980814	116	45.83	7	102	6	101	9.0e-18	82.2	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
649980815	593	39.35	8	466	3	456	3.0e-112	399	COG2812	DNA polymerase III, gamma/tau subunits	515
649980816	360	23.8	5	354	3	321	3.0e-28	119	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
649980820	423	22.12	3	396	1	395	3.0e-12	66.9	COG4102	Uncharacterized conserved protein, DUF1501 family	418
649980821	226	24.28	51	220	6	178	4.0e-16	78.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649980823	429	44.2	6	405	2	394	2.0e-109	389	COG0019	Diaminopimelate decarboxylase	394
649980825	834	21.05	7	796	2	737	1.0e-29	125	COG2409	Uncharacterized membrane protein YdfJ, MMPL/SSD domain	937
649980826	328	44.3	15	326	20	320	6.0e-94	337	COG0379	Quinolinate synthase	324
649980833	640	41.63	27	620	22	604	0.0e+00	486	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
649980845	240	20.18	28	233	11	214	5.0e-13	68.4	COG2755	Lysophospholipase L1 or related esterase	216
649980846	810	31.98	79	606	1	458	2.0e-76	280	COG3119	Arylsulfatase A or related enzyme	475
649980854	312	25.59	1	282	2	288	2.0e-26	113	COG0657	Acetyl esterase/lipase	312
649980859	214	42.27	1	192	6	199	2.0e-46	178	COG4430	Uncharacterized conserved protein YdeI, YjbR/CyaY-like superfamily, DUF1801 family	200
649980865	374	30.82	48	361	14	329	9.0e-58	217	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
649980866	197	42.27	1	193	1	190	6.0e-55	206	COG0066	3-isopropylmalate dehydratase small subunit	191
649980867	473	49.89	5	468	3	423	0.0e+00	577	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
649980868	336	38.58	1	334	1	336	2.0e-91	329	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
649980869	296	36.03	1	292	1	293	8.0e-39	154	COG0583	DNA-binding transcriptional regulator, LysR family	297
649980872	839	35.07	10	816	28	873	0.0e+00	564	COG3002	Uncharacterized conserved protein YbcC, UPF0753/DUF2309 family	880
649980873	1253	22.54	910	1218	8	280	1.0e-13	73.1	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
649980876	310	61.39	3	302	1	300	4.0e-115	408	COG0031	Cysteine synthase	300
649980878	165	20.99	1	158	1	159	1.0e-03	36.1	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
649980879	428	61.31	1	428	2	430	0.0e+00	631	COG0001	Glutamate-1-semialdehyde aminotransferase	432
649980880	235	20.99	14	206	20	251	2.0e-03	36.3	COG1082	Sugar phosphate isomerase/epimerase	274
649980881	459	36.95	1	331	2	340	3.0e-58	219	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649980882	254	32.47	19	249	7	222	4.0e-28	118	COG1040	Predicted amidophosphoribosyltransferases	225
649980883	196	25.32	5	82	4	82	2.0e-07	49	COG3830	ACT domain, binds amino acids and other small ligands	90
649980884	459	22.96	44	421	15	353	1.0e-30	127	COG0628	Predicted PurR-regulated permease PerM	355
649980885	729	20.35	35	255	5	206	8.0e-08	53	COG2755	Lysophospholipase L1 or related esterase	216
649980886	448	22.12	120	343	29	235	1.0e-08	55	COG3063	Tfp pilus assembly protein PilF	250
649980888	175	27.38	6	160	2	167	2.0e-18	85.7	COG1443	Isopentenyldiphosphate isomerase	185
649980889	1126	22.26	128	453	95	393	1.0e-16	82.8	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
649980892	1289	20.3	473	769	68	383	8.0e-09	56.9	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
649980893	329	32.53	6	329	1	308	1.0e-38	154	COG0524	Sugar or nucleoside kinase, ribokinase family	311
649980894	397	40.94	124	393	1	276	8.0e-78	284	COG0077	Prephenate dehydratase	279
649980895	637	59.33	6	604	5	579	0.0e+00	650	COG0443	Molecular chaperone DnaK (HSP70)	579
649980896	884	52.05	7	879	1	783	0.0e+00	895	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
649980897	284	45.85	1	283	1	295	3.0e-82	298	COG2321	Predicted metalloprotease	295
649980899	448	16.67	45	393	43	388	2.0e-11	64.5	COG2814	Predicted arabinose efflux permease, MFS family	394
649980901	291	25.28	23	291	6	268	1.0e-27	117	COG4587	ABC-type uncharacterized transport system, permease component	268
649980902	333	46.73	1	321	1	321	5.0e-94	338	COG4586	ABC-type uncharacterized transport system, ATPase component	325
649980903	693	31.24	144	570	17	390	3.0e-71	263	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
649980904	341	32.77	34	320	27	312	8.0e-39	154	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
650641368	230	24.44	1	214	19	240	3.0e-25	108	COG3751	Proline 4-hydroxylase (includes Rps23 Pro-64 3,4-dihydroxylase Tpa1), contains SM-20 domain	252
650641371	227	20.37	5	227	16	284	3.0e-16	78.8	COG0863	DNA modification methylase	302
650641380	301	25.37	7	132	5	138	4.0e-07	49.3	COG2165	Type II secretory pathway, pseudopilin PulG	149
650641386	717	23.65	100	383	10	279	1.0e-25	112	COG0515	Serine/threonine protein kinase	384
650641403	405	21.92	127	369	46	296	3.0e-09	56.4	COG4974	Site-specific recombinase XerD	300
650641404	384	20.36	14	180	1	158	2.0e-14	74	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650641415	510	25.76	173	448	21	295	2.0e-16	81	COG4974	Site-specific recombinase XerD	300
