gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
639000518	242	24.79	4	241	9	243	5.0e-11	61.7	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
639000519	255	41.4	14	228	1	213	1.0e-35	143	COG0811	Biopolymer transport protein ExbB/TolQ	216
639000520	167	33.1	1	142	1	137	6.0e-31	126	COG0848	Biopolymer transport protein ExbD	137
639000521	179	33.81	21	150	44	180	1.0e-22	99	COG1525	Endonuclease YncB, thermonuclease family	192
639000524	133	52.04	1	98	1	98	5.0e-21	93.4	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
639000526	1868	45.01	10	964	6	935	0.0e+00	1088	COG0178	Excinuclease UvrABC ATPase subunit	935
639000529	263	37.25	109	261	39	190	2.0e-27	116	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
639000531	284	43.43	8	257	7	257	4.0e-70	258	COG0796	Glutamate racemase	269
639000534	313	33.88	1	304	4	290	3.0e-65	242	COG1131	ABC-type multidrug transport system, ATPase component	293
639000535	965	18.95	422	952	33	537	2.0e-15	78.9	COG3225	ABC-type uncharacterized transport system involved in gliding motility, auxiliary component	538
639000537	353	41.6	117	351	81	315	2.0e-52	200	COG2829	Outer membrane phospholipase A	317
639000538	107	40.91	4	65	5	68	2.0e-08	50.9	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
639000539	205	33.33	1	204	1	207	4.0e-35	141	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
639000540	202	21.15	1	199	5	229	4.0e-06	44.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
639000548	230	48.68	41	229	1	189	5.0e-42	164	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
639000554	634	44.92	1	522	3	530	0.0e+00	519	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
639000555	655	30.05	30	655	67	861	0.0e+00	472	COG1048	Aconitase A	861
639000556	179	34.25	1	179	5	171	9.0e-25	106	COG3065	Starvation-inducible outer membrane lipoprotein	191
639000557	612	17.42	144	545	22	428	5.0e-09	56.5	COG5421	Transposase	480
639000561	588	29.63	275	533	63	315	2.0e-25	110	COG4257	Streptogramin lyase	353
639000562	447	34.55	24	446	2	391	1.0e-62	234	COG0183	Acetyl-CoA acetyltransferase	392
639000563	726	41.84	20	214	8	199	8.0e-36	145	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
639000563	726	44.04	327	624	1	301	4.0e-81	296	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
639000572	697	26.06	546	693	60	223	6.0e-06	46.6	COG1040	Predicted amidophosphoribosyltransferases	225
639000572	697	36.61	1	482	1	459	6.0e-95	342	COG0514	Superfamily II DNA helicase RecQ	590
639000573	457	26.69	54	344	37	328	6.0e-41	162	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
639000575	88	46.75	7	83	8	84	2.0e-20	90.4	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
639000576	97	41.77	14	92	3	81	8.0e-13	65.4	COG3905	Predicted transcriptional regulator	83
639000577	98	31.63	1	95	1	92	1.0e-08	51.6	COG3668	Plasmid stabilization system protein ParE	98
639000585	69	63.77	1	69	1	69	3.0e-23	100	COG3360	Flavin-binding protein dodecin	71
639000587	466	27.46	32	309	15	298	6.0e-32	132	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
639000588	551	28.31	79	449	24	390	8.0e-52	198	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
639000589	146	29.71	1	126	1	138	4.0e-15	74.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
639000590	384	36.57	1	384	7	388	3.0e-84	305	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
639000592	304	22.8	1	295	1	305	2.0e-24	106	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
639000593	257	51.63	1	246	4	249	2.0e-81	295	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
639000594	364	41	99	359	8	263	2.0e-58	220	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
639000595	531	56.48	23	516	1	494	0.0e+00	727	COG0554	Glycerol kinase	499
639000596	154	73.38	1	154	1	154	4.0e-58	217	COG2193	Bacterioferritin (cytochrome b1)	157
639000597	435	46.35	12	434	12	435	5.0e-129	454	COG1362	Aspartyl aminopeptidase	437
639000598	332	37.5	95	329	1	236	3.0e-43	168	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
639000599	250	34.78	1	247	1	249	2.0e-39	155	COG1521	Pantothenate kinase type III	251
639000606	945	31.93	459	934	174	641	6.0e-75	276	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
639000607	109	28.74	9	92	3	89	5.0e-10	56.4	COG1343	CRISPR/Cas system-associated endoribonuclease Cas2	89
639000615	301	31.33	8	298	5	294	5.0e-46	178	COG1336	CRISPR/Cas system CMR subunit Cmr4, Cas7 group, RAMP superfamily	298
639000616	384	20.86	6	344	4	306	2.0e-17	83.9	COG1769	CRISPR/Cas system CMR-associated protein Cmr3, group 5 of RAMP superfamily	335
639000621	578	21.36	21	503	29	441	2.0e-09	58.1	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
639000625	401	22.85	4	366	15	374	2.0e-31	130	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
639000626	351	21.96	5	286	2	285	3.0e-18	86.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
639000628	414	34.38	36	412	33	404	2.0e-83	302	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
639000629	540	40.46	23	540	4	488	0.0e+00	512	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
639000630	679	42.16	476	660	1	181	1.0e-43	171	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
639000634	399	32.28	70	352	85	357	2.0e-42	166	COG4850	Phosphatidate phosphatase APP1	373
639000635	321	39.44	3	321	3	322	5.0e-64	238	COG0598	Mg2+ and Co2+ transporter CorA	322
639000636	540	27.19	15	226	23	235	8.0e-28	118	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
639000638	971	37.77	16	247	4	225	5.0e-34	140	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
639000639	384	27.82	28	376	15	366	2.0e-28	120	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639000640	389	27.84	26	376	13	374	1.0e-28	120	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639000641	604	31.27	1	560	1	518	1.0e-91	330	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
639000642	370	25.86	7	366	4	374	5.0e-30	125	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639000648	98	49.45	2	92	1	90	2.0e-23	100	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
639000654	151	52.32	1	151	2	150	1.0e-46	178	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
639000655	258	34.63	10	256	11	265	5.0e-41	161	COG0300	Short-chain dehydrogenase	265
639000656	262	33.49	12	217	18	223	1.0e-32	133	COG3555	Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily	291
639000657	937	30.09	703	925	3	223	2.0e-25	111	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
639000657	937	30.4	114	674	7	534	9.0e-83	302	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
639000659	641	42.21	1	526	1	526	0.0e+00	517	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
639000660	553	52.32	7	537	8	541	0.0e+00	501	COG2303	Choline dehydrogenase or related flavoprotein	542
639000663	193	39.6	24	170	19	162	4.0e-32	131	COG4067	Uncharacterized conserved protein	162
639000669	285	31.14	1	220	21	243	2.0e-45	176	COG1718	Serine/threonine-protein kinase RIO1	268
639000673	384	41.78	7	377	1	349	8.0e-104	370	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
639000674	606	27.84	23	604	7	567	1.0e-76	281	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
639000676	106	39.05	1	103	2	106	8.0e-19	85.4	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
639000679	301	32.41	18	147	6	150	1.0e-09	57.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
639000680	153	38.54	8	103	1	96	2.0e-18	85.3	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
639000681	93	50.56	4	92	1	89	1.0e-10	58.2	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
639000682	146	32.88	1	146	14	158	8.0e-29	119	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
639000683	547	35	5	536	1	502	2.0e-56	213	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
639000684	114	53.1	1	113	1	112	3.0e-25	106	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
639000685	974	41.28	615	784	2	162	6.0e-19	90.4	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
639000685	974	44	10	556	4	541	5.0e-119	422	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
639000687	372	38.75	15	93	9	88	1.0e-14	74.6	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
639000688	397	24.26	2	313	19	339	5.0e-25	109	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
639000690	338	39.54	33	335	4	293	3.0e-70	258	COG1131	ABC-type multidrug transport system, ATPase component	293
639000693	224	41.7	1	217	1	221	3.0e-43	168	COG2135	Putative SOS response-associated peptidase YedK	226
639000694	481	28.74	1	480	2	489	9.0e-62	231	COG0286	Type I restriction-modification system, DNA methylase subunit	489
639000696	172	33.57	1	143	1	136	2.0e-25	108	COG1943	REP element-mobilizing transposase RayT	136
639000698	496	17	10	460	1	391	3.0e-15	77	COG0732	Restriction endonuclease S subunit	391
639000699	921	24.56	2	895	10	866	2.0e-114	407	COG4096	Type I site-specific restriction endonuclease, part of a restriction-modification system	875
639000700	194	33.15	17	194	20	197	4.0e-23	101	COG3932	Uncharacterized conserved protein	209
639000701	184	26.06	5	169	2	163	9.0e-19	86.9	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
639000702	430	41.42	48	426	1	377	1.0e-75	277	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
639000703	363	34.35	31	358	11	332	4.0e-62	232	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
639000706	240	20.91	125	234	11	109	3.0e-06	45.7	COG0607	Rhodanese-related sulfurtransferase	110
639000710	500	38.7	7	482	3	469	1.0e-119	423	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
639000711	239	37.5	1	231	1	227	3.0e-30	125	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
639000712	249	46.92	1	249	1	260	6.0e-65	240	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
639000713	315	51.74	1	311	1	312	4.0e-78	285	COG2025	Electron transfer flavoprotein, alpha subunit	313
639000715	126	31.36	10	126	2	119	1.0e-19	88.7	COG1539	Dihydroneopterin aldolase	121
639000716	198	29.8	18	191	3	199	5.0e-11	61.1	COG0778	Nitroreductase	207
639000718	429	29.2	1	382	1	381	3.0e-42	166	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639000720	72	35.82	1	67	1	66	1.0e-11	61.5	COG3360	Flavin-binding protein dodecin	71
639000727	320	33.33	6	296	1	290	5.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
639000728	211	28.3	3	207	2	205	4.0e-34	138	COG0288	Carbonic anhydrase	207
639000731	476	49.67	6	460	1	429	0.0e+00	542	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
639000732	111	35.79	12	106	9	103	1.0e-20	91.6	COG4451	Ribulose bisphosphate carboxylase small subunit	127
639000736	85	33.73	1	76	1	83	2.0e-10	57.2	COG4576	Carboxysome shell and ethanolamine utilization microcompartment protein CcmK/EutM	89
639000737	114	33.73	1	77	1	83	1.0e-08	51.5	COG4576	Carboxysome shell and ethanolamine utilization microcompartment protein CcmK/EutM	89
639000742	188	32.14	7	146	4	143	1.0e-20	93	COG2193	Bacterioferritin (cytochrome b1)	157
639000747	108	21.36	9	106	1	102	1.0e-09	55.2	COG0347	Nitrogen regulatory protein PII	112
639000749	189	24.19	46	165	10	122	2.0e-06	45.8	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
639000758	70	40	4	63	3	61	1.0e-09	54.6	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
639000760	182	20.49	4	167	1	205	2.0e-08	52.5	COG1335	Nicotinamidase-related amidase	205
639000762	291	25.16	8	282	2	305	2.0e-20	93.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
639000765	569	45.36	1	545	1	481	0.0e+00	543	COG0442	Prolyl-tRNA synthetase	500
639000767	164	53.09	1	162	3	163	2.0e-46	178	COG0440	Acetolactate synthase, small subunit	163
639000768	338	66.17	1	334	3	336	0.0e+00	543	COG0059	Ketol-acid reductoisomerase	338
639000769	266	40.83	17	254	6	234	2.0e-46	179	COG1183	Phosphatidylserine synthase	234
639000770	516	50.24	5	417	1	409	6.0e-118	418	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
639000771	265	46.5	67	255	1	200	2.0e-45	175	COG1573	Uracil-DNA glycosylase	202
639000772	160	32.52	1	144	3	165	3.0e-18	85.1	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
639000773	413	34.71	2	402	17	428	2.0e-73	269	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
639000775	517	27.89	1	438	24	460	8.0e-29	122	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
639000776	98	54.55	4	91	22	109	2.0e-23	100	COG3952	Uncharacterized N-terminal domain of lipid-A-disaccharide synthase	113
639000777	242	28.64	1	216	3	210	4.0e-19	88.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
639000778	919	52.98	1	918	1	877	0.0e+00	1204	COG0525	Valyl-tRNA synthetase	877
639000779	144	38.46	5	141	2	141	4.0e-22	97.3	COG2927	DNA polymerase III, chi subunit	144
639000780	499	49.6	1	496	1	485	0.0e+00	549	COG0260	Leucyl aminopeptidase	485
639000781	357	30.7	10	339	17	358	4.0e-34	138	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
639000782	358	31.04	1	356	1	364	4.0e-46	179	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
639000783	158	28.06	17	154	13	148	2.0e-07	48.6	COG1714	Uncharacterized membrane protein YckC, RDD family	172
639000785	475	40.29	60	470	1	407	2.0e-85	310	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
639000786	165	49.69	6	164	1	158	6.0e-45	173	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
639000787	274	48.29	13	274	1	263	1.0e-90	326	COG0413	Ketopantoate hydroxymethyltransferase	268
639000788	286	52.28	1	283	1	285	5.0e-97	347	COG0414	Panthothenate synthetase	285
639000789	133	48	9	133	1	125	3.0e-41	160	COG0853	Aspartate 1-decarboxylase	126
639000790	357	51.6	12	352	1	337	8.0e-100	357	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
639000791	491	42.36	5	203	1	203	6.0e-44	172	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
639000791	491	45.07	215	490	1	283	8.0e-59	221	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
639000792	153	51.03	7	150	5	149	9.0e-38	149	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
639000793	424	35.42	96	366	2	228	6.0e-47	181	COG0860	N-acetylmuramoyl-L-alanine amidase	231
639000794	632	44.83	14	631	3	638	0.0e+00	627	COG0323	DNA mismatch repair ATPase MutL	638
639000795	303	50	1	286	9	292	3.0e-88	318	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
639000796	85	71.23	1	72	1	73	1.0e-23	101	COG1923	sRNA-binding regulator protein Hfq	77
639000797	435	49.27	15	424	3	406	2.0e-119	422	COG2262	50S ribosomal subunit-associated GTPase HflX	411
639000798	411	33.22	65	355	3	283	2.0e-45	177	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
639000799	290	28.47	8	288	6	288	8.0e-45	174	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
639000800	62	37.1	1	62	1	62	4.0e-08	49.8	COG3242	Uncharacterized conserved protein YjeT, DUF2065 family	62
639000801	399	34.69	11	399	2	388	1.0e-72	267	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
639000802	431	59.07	2	430	1	430	0.0e+00	637	COG0104	Adenylosuccinate synthase	430
639000804	247	34.59	58	239	38	221	3.0e-09	55.6	COG0671	Membrane-associated phospholipid phosphatase	232
639000805	367	30.43	87	358	21	255	2.0e-30	126	COG1237	Metal-dependent hydrolase, beta-lactamase superfamily II	259
639000806	341	20.18	6	341	5	319	1.0e-17	84.1	COG0530	Ca2+/Na+ antiporter	320
639000812	511	29.48	11	488	21	512	2.0e-72	267	COG0659	Sulfate permease or related transporter, MFS superfamily	554
639000814	137	41.35	5	106	2	105	2.0e-22	97.7	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
639000815	815	58.9	6	808	1	789	0.0e+00	1099	COG1251	NAD(P)H-nitrite reductase, large subunit	793
639000819	671	19.29	2	671	54	768	3.0e-31	130	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
639000821	293	39.08	7	282	5	287	2.0e-63	236	COG1131	ABC-type multidrug transport system, ATPase component	293
639000822	369	33.04	243	357	13	127	5.0e-18	85.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
639000823	2190	34.85	1363	2014	1	642	5.0e-120	427	COG1020	Non-ribosomal peptide synthetase component F	642
639000824	1833	35.83	292	941	1	642	5.0e-116	413	COG1020	Non-ribosomal peptide synthetase component F	642
639000825	588	36.8	19	573	15	565	3.0e-101	362	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
639000826	580	33.33	23	565	22	563	2.0e-94	340	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
639000830	386	39.77	26	369	5	347	6.0e-71	261	COG4693	Oxidoreductase (NAD-binding), involved in siderophore biosynthesis	361
639000832	535	52.16	1	529	4	536	0.0e+00	638	COG1021	Non-ribosomal peptide synthetase component E (peptide arylation enzyme)	542
639000833	253	44.44	15	245	1	233	4.0e-58	218	COG3208	Surfactin synthase thioesterase subunit	244
639000834	101	29.7	1	99	1	101	9.0e-15	71.9	COG1605	Chorismate mutase	101
639000835	458	38.26	50	457	40	418	1.0e-86	314	COG1169	Isochorismate synthase EntC	423
639000843	818	36.9	17	815	43	880	0.0e+00	578	COG3002	Uncharacterized conserved protein YbcC, UPF0753/DUF2309 family	880
639000850	166	38.89	11	114	3	110	5.0e-14	70.9	COG5556	Uncharacterized protein	110
639000853	243	50.67	7	226	4	219	2.0e-66	245	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
639000854	225	33.64	16	221	4	212	1.0e-40	160	COG0602	Organic radical activating enzyme	212
639000855	275	26.77	1	268	26	259	4.0e-27	115	COG1729	Periplasmic TolA-binding protein (function unknown)	262
639000857	433	38.93	7	433	1	424	2.0e-86	313	COG0823	Periplasmic component of the Tol biopolymer transport system	425
639000859	142	43.17	1	139	3	135	7.0e-31	126	COG0848	Biopolymer transport protein ExbD	137
639000860	234	40.28	10	219	1	211	1.0e-46	179	COG0811	Biopolymer transport protein ExbB/TolQ	216
639000861	149	34.56	10	145	3	131	2.0e-25	108	COG0824	Acyl-CoA thioesterase FadM	137
639000862	719	26.96	21	718	55	783	2.0e-97	350	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
639000863	430	20.12	6	341	3	320	2.0e-15	77.4	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
639000864	343	54.94	10	331	4	327	2.0e-110	392	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
639000865	271	43.3	5	264	3	259	1.0e-74	273	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
639000866	127	56.56	6	127	5	126	1.0e-42	165	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
639000868	340	43.52	3	333	4	348	3.0e-85	308	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
639000871	222	52.5	15	212	11	210	4.0e-68	251	COG0321	Lipoate-protein ligase B	221
639000872	340	46.63	1	337	44	383	6.0e-101	360	COG1686	D-alanyl-D-alanine carboxypeptidase	389
639000873	259	45.18	22	174	50	214	4.0e-40	158	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
639000874	337	35.87	20	332	30	338	2.0e-75	276	COG2951	Membrane-bound lytic murein transglycosylase B	343
639000875	376	47.67	24	376	14	377	6.0e-80	291	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
639000876	616	38.45	13	614	10	589	0.0e+00	492	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
639000877	134	39.69	5	134	33	163	2.0e-16	77.9	COG2891	Cell shape-determining protein MreD	167
639000878	270	39.92	1	247	24	271	6.0e-51	194	COG1792	Cell shape-determining protein MreC	284
639000879	347	64.07	6	337	2	333	4.0e-125	441	COG1077	Actin-like ATPase involved in cell morphogenesis	342
639000880	95	40	1	95	1	95	1.0e-17	81.4	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
639000881	484	54.38	1	481	4	475	0.0e+00	522	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
639000882	477	61.51	1	476	4	481	0.0e+00	734	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
639000883	266	51.98	1	246	3	253	2.0e-71	262	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
639000884	262	30.46	21	217	12	205	3.0e-23	102	COG0811	Biopolymer transport protein ExbB/TolQ	216
639000886	133	31.75	7	131	10	134	9.0e-14	69.1	COG0848	Biopolymer transport protein ExbD	137
639000887	307	28.36	107	307	48	244	2.0e-13	70.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
639000889	612	18.46	144	542	22	425	1.0e-16	81.5	COG5421	Transposase	480
639000890	1283	23.17	399	678	1	306	6.0e-20	94.1	COG0515	Serine/threonine protein kinase	384
639000892	79	40.79	4	79	2	74	2.0e-08	50.7	COG4456	Virulence-associated protein VagC (function unknown)	74
639000893	135	36.92	4	133	3	130	4.0e-20	90.6	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
639000897	694	29.6	10	688	3	715	3.0e-97	349	COG1201	Lhr-like helicase	814
639000899	81	42.11	1	76	2	77	4.0e-10	56.6	COG4118	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor	84
639000900	125	47.2	3	123	4	128	4.0e-32	130	COG3744	PIN domain nuclease, a component of toxin-antitoxin system (PIN domain)	130
639000902	773	48.45	23	726	1	705	0.0e+00	673	COG0557	Exoribonuclease R	706
639000903	256	42.8	6	247	23	259	1.0e-59	223	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
639000904	141	46.36	2	110	1	110	2.0e-30	124	COG0360	Ribosomal protein S6	112
639000905	117	42.71	18	113	5	100	5.0e-16	76.5	COG2965	Primosomal replication protein N	103
639000906	74	72.06	1	68	8	75	7.0e-21	92.2	COG0238	Ribosomal protein S18	75
639000908	149	49.32	1	148	1	147	7.0e-43	166	COG0359	Ribosomal protein L9	148
639000909	461	52.29	15	450	1	433	0.0e+00	555	COG0305	Replicative DNA helicase	435
639000910	365	45.58	1	357	1	360	7.0e-106	377	COG0787	Alanine racemase	360
639000911	286	56.18	4	286	1	283	5.0e-110	391	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
639000917	475	38.64	23	454	1	438	3.0e-87	316	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
639000918	214	68.18	16	213	3	200	1.0e-83	302	COG0740	ATP-dependent protease ClpP, protease subunit	200
639000919	425	70.76	19	424	1	407	0.0e+00	691	COG1219	ATP-dependent protease Clp, ATPase subunit	408
639000920	811	67.57	12	783	9	782	0.0e+00	1184	COG0466	ATP-dependent Lon protease, bacterial type	782
639000921	90	66.67	1	90	2	91	2.0e-29	120	COG0776	Bacterial nucleoid DNA-binding protein	94
639000925	266	61.63	1	258	1	256	4.0e-106	377	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
639000926	476	49	1	446	2	444	0.0e+00	519	COG1160	Predicted GTPases	444
639000927	292	28.89	19	129	14	135	1.0e-06	47.3	COG3474	Cytochrome c2	135
639000928	1218	51.23	11	1218	29	1227	0.0e+00	1478	COG5013	Nitrate reductase alpha subunit	1227
639000929	512	51.77	1	506	1	483	0.0e+00	655	COG1140	Nitrate reductase beta subunit	513
639000930	256	27.27	6	148	5	144	1.0e-19	90	COG2180	Nitrate reductase assembly protein NarJ, required for insertion of molybdenum cofactor	179
639000931	216	35.12	1	199	15	219	6.0e-23	101	COG2181	Nitrate reductase gamma subunit	228
639000933	339	40.67	16	331	12	337	1.0e-67	250	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
639000934	645	43.35	67	621	1	525	0.0e+00	668	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
639000936	370	39.9	1	370	12	391	1.0e-88	320	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
639000937	261	38.89	1	248	1	235	1.0e-35	143	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
639000938	129	45	5	124	24	143	6.0e-33	133	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
639000939	1170	34.43	1	1168	1	1163	0.0e+00	570	COG1196	Chromosome segregation ATPase	1163
639000940	296	25.53	1	288	1	323	7.0e-30	124	COG3115	Cell division protein ZipA, interacts with FtsZ	324
639000941	672	54.59	7	669	5	666	0.0e+00	872	COG0272	NAD-dependent DNA ligase	667
639000942	97	40.23	8	94	7	90	7.0e-18	81.9	COG0271	Stress-induced morphogen (activity unknown)	90
639000943	99	55.1	1	98	1	92	3.0e-21	93.4	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
639000944	207	44.17	3	207	2	206	6.0e-52	197	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
639000946	294	43.51	44	277	1	239	4.0e-48	185	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
639000947	198	51.93	4	183	8	184	6.0e-45	173	COG1386	Chromosome segregation and condensation protein ScpB	184
639000948	267	44.35	5	246	3	247	9.0e-61	227	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
639000950	262	33.03	20	235	3	215	2.0e-29	123	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
639000951	284	32.13	1	274	7	283	1.0e-30	127	COG1562	Phytoene/squalene synthetase	288
639000952	273	36.41	42	255	5	218	6.0e-39	154	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
639000953	234	56.71	4	231	11	240	1.0e-80	292	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
639000954	448	42.62	16	427	3	413	3.0e-86	312	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
639000955	336	49.56	4	334	1	343	2.0e-109	389	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
639000956	185	42.59	26	185	1	157	9.0e-42	163	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
639000958	852	56.74	1	841	1	802	0.0e+00	1036	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
639000959	360	55.49	1	360	3	365	0.0e+00	484	COG1932	Phosphoserine aminotransferase	365
639000960	389	37.69	1	316	3	324	4.0e-58	219	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
639000961	361	41.41	1	98	4	101	2.0e-18	86.9	COG1605	Chorismate mutase	101
639000961	361	48.73	90	359	1	275	5.0e-92	331	COG0077	Prephenate dehydratase	279
639000962	388	44.35	16	383	4	356	4.0e-90	325	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
639000963	291	42.4	5	285	4	279	2.0e-68	252	COG0287	Prephenate dehydrogenase	279
639000964	411	44.66	1	402	31	428	1.0e-99	357	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
639000965	230	48.42	6	225	4	220	2.0e-64	238	COG0283	Cytidylate kinase	222
639000966	563	58.7	1	551	1	540	0.0e+00	596	COG0539	Ribosomal protein S1	541
639000967	107	49.47	1	95	1	94	4.0e-31	126	COG0776	Bacterial nucleoid DNA-binding protein	94
639000968	98	34.29	7	76	27	96	1.0e-05	41	COG5416	Uncharacterized integral membrane protein	98
639000969	249	46.81	11	245	8	239	6.0e-61	227	COG0284	Orotidine-5'-phosphate decarboxylase	240
639000971	317	59.86	28	315	2	287	2.0e-117	415	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
639000975	174	45.71	5	174	7	179	1.0e-36	145	COG2032	Cu/Zn superoxide dismutase	179
639000977	396	41.21	7	393	1	389	6.0e-104	371	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
639000978	676	65.61	1	662	1	656	0.0e+00	1062	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
639000980	641	54.17	34	632	1	581	0.0e+00	738	COG0441	Threonyl-tRNA synthetase	589
639000981	177	59.09	1	176	1	176	4.0e-62	230	COG0290	Translation initiation factor IF-3	176
639000982	80	58.46	16	80	1	65	6.0e-14	69.1	COG0291	Ribosomal protein L35	65
639000983	118	72.03	1	118	1	118	7.0e-40	155	COG0292	Ribosomal protein L20	118
639000984	342	52.92	6	340	4	335	3.0e-121	428	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
639000985	793	42.66	144	792	2	650	0.0e+00	641	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
639000986	100	46.24	2	94	1	93	4.0e-28	116	COG0776	Bacterial nucleoid DNA-binding protein	94
639000987	118	25.49	19	118	1	101	6.0e-09	52.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
639000990	612	18.56	144	545	22	428	3.0e-16	80.7	COG5421	Transposase	480
639000991	172	28.8	22	126	14	138	2.0e-10	58.7	COG0221	Inorganic pyrophosphatase	171
639000992	124	34.17	3	112	1	120	5.0e-10	56.7	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
639000997	327	49.06	1	316	1	306	2.0e-93	335	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
639001001	135	34.06	2	135	4	138	9.0e-19	85.8	COG5573	Predicted nucleic acid-binding protein, contains PIN domain	142
639001005	144	28.99	1	136	1	135	9.0e-16	76.3	COG1848	Predicted nucleic acid-binding protein, contains PIN domain	140
639001006	1711	36.8	170	734	1	519	2.0e-123	438	COG1640	4-alpha-glucanotransferase	520
639001006	1711	44.59	748	1708	2	888	0.0e+00	863	COG3280	Maltooligosyltrehalose synthase	889
639001007	610	31.92	1	604	18	626	2.0e-124	439	COG0296	1,4-alpha-glucan branching enzyme	628
639001008	731	56.2	34	729	12	696	0.0e+00	848	COG1523	Pullulanase/glycogen debranching enzyme	697
639001009	1129	32.65	35	538	1	505	5.0e-90	326	COG0366	Glycosidase	505
639001009	1129	36.77	744	1121	76	430	1.0e-64	242	COG3281	Predicted trehalose synthase	438
639001010	666	17.71	201	608	1	495	3.0e-21	97	COG0366	Glycosidase	505
639001011	647	54.82	19	644	6	628	0.0e+00	732	COG0296	1,4-alpha-glucan branching enzyme	628
639001013	210	21.4	16	205	31	234	3.0e-22	98.8	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
639001014	216	41.97	14	195	3	195	6.0e-47	180	COG0132	Dethiobiotin synthetase	223
639001015	432	43.55	11	432	12	444	1.0e-129	456	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
639001017	430	47.4	1	192	2	187	7.0e-50	191	COG2715	Spore maturation protein SpmA (function unknown)	206
639001018	121	42.86	6	113	1	111	1.0e-18	85.4	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
639001019	86	48.75	6	84	1	80	2.0e-15	73.8	COG2336	Antitoxin component of the MazEF toxin-antitoxin module	82
639001021	461	33.18	46	457	18	434	8.0e-65	241	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
639001022	250	31.54	24	168	31	176	1.0e-12	66.8	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
639001023	506	52.59	23	503	2	470	0.0e+00	518	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
639001025	447	25.92	41	435	43	450	6.0e-25	109	COG1538	Outer membrane protein TolC	457
639001026	500	30.25	197	483	46	355	1.0e-21	98.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
639001027	1078	46.37	16	1060	2	1024	0.0e+00	1064	COG3696	Cu/Ag efflux pump CusA	1027
639001028	136	31.34	1	130	2	129	1.0e-06	45.7	COG4113	Predicted nucleic acid-binding protein, contains PIN domain	134
639001033	366	27.05	25	344	53	373	2.0e-27	117	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639001036	374	30.59	4	372	6	326	2.0e-33	136	COG0306	Phosphate/sulfate permease	326
639001045	114	62.62	7	113	3	109	1.0e-26	111	COG1742	Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily	109
639001046	214	25.35	4	204	5	217	3.0e-29	121	COG1230	Co/Zn/Cd efflux system component	296
639001051	217	52.28	8	204	1	197	1.0e-61	229	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
639001052	674	24.58	20	311	18	308	7.0e-24	106	COG3447	Integral membrane sensor domain MASE1	308
639001053	725	21.62	234	682	147	556	2.0e-35	144	COG0747	ABC-type transport system, periplasmic component	556
639001054	325	34.64	1	325	1	316	2.0e-51	196	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
639001055	462	36.33	216	460	65	289	2.0e-44	173	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
639001056	696	50.5	350	652	3	258	2.0e-101	364	COG4608	ABC-type oligopeptide transport system, ATPase component	309
639001056	696	55.49	5	318	1	316	2.0e-119	423	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
639001060	150	27.27	24	111	10	97	9.0e-06	42.9	COG1669	Predicted nucleotidyltransferase	97
639001061	144	28.15	1	135	3	131	5.0e-12	63.7	COG2445	Uncharacterized conserved protein YutE, UPF0331/DUF86 family	138
639001068	354	27.17	12	352	2	342	1.0e-50	193	COG0673	Predicted dehydrogenase	342
639001072	518	41.24	160	518	1	369	3.0e-103	369	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
639001073	435	21.13	5	428	1	426	4.0e-21	96.3	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
639001074	309	31.91	1	295	17	310	2.0e-44	173	COG0451	Nucleoside-diphosphate-sugar epimerase	314
639001075	383	34.51	15	375	2	351	3.0e-85	309	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
639001076	383	25.52	1	380	3	381	2.0e-54	206	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
639001077	367	43.66	11	365	13	341	1.0e-102	366	COG2089	Sialic acid synthase SpsE, contains C-terminal SAF domain	347
639001080	229	42.4	6	220	3	217	9.0e-49	187	COG1083	CMP-N-acetylneuraminic acid synthetase	228
639001083	202	48.26	3	202	6	202	6.0e-64	236	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
639001084	253	35.77	1	243	1	246	2.0e-60	225	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
639001085	360	19.18	39	319	5	289	2.0e-09	57.2	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
639001087	345	24.5	17	344	50	381	1.0e-20	94.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639001088	414	22.33	1	404	1	375	3.0e-20	93.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639001089	285	26.17	1	283	1	278	2.0e-43	169	COG1091	dTDP-4-dehydrorhamnose reductase	281
639001091	371	35.09	1	371	7	383	5.0e-99	354	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
639001092	300	31.58	2	293	16	305	3.0e-32	132	COG0451	Nucleoside-diphosphate-sugar epimerase	314
639001093	336	26.64	1	296	3	301	3.0e-36	145	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
639001095	128	30.91	68	122	6	60	2.0e-06	44.8	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
639001098	140	28.15	3	137	4	129	3.0e-09	54.6	COG4113	Predicted nucleic acid-binding protein, contains PIN domain	134
639001101	194	24.55	10	170	12	171	8.0e-08	50.4	COG2930	Lipid-binding SYLF domain	227
639001102	396	27.79	1	379	3	380	8.0e-35	141	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
639001108	487	27.49	25	482	8	520	2.0e-35	144	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
639001109	728	28.32	3	226	1	219	2.0e-28	121	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
639001109	728	40.04	236	687	3	454	3.0e-119	423	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
639001113	333	31.88	28	331	17	309	3.0e-41	162	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
639001115	415	49.64	1	415	1	408	1.0e-111	396	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
639001116	224	48.61	2	216	11	226	4.0e-70	257	COG1136	ABC-type lipoprotein export system, ATPase component	226
639001118	184	30.11	1	174	4	179	3.0e-27	114	COG3216	Uncharacterized conserved protein, DUF2062 family	184
639001119	756	37.8	498	741	38	284	2.0e-59	224	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
639001120	200	31.96	1	193	23	216	4.0e-31	128	COG0811	Biopolymer transport protein ExbB/TolQ	216
639001121	140	35.46	1	138	1	135	3.0e-25	107	COG0848	Biopolymer transport protein ExbD	137
639001122	597	42.78	17	584	2	563	0.0e+00	463	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
639001123	331	43.92	1	328	3	336	1.0e-82	300	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
639001124	258	51.18	4	257	2	246	3.0e-82	298	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
639001125	150	43.45	1	145	10	139	3.0e-28	117	COG0394	Protein-tyrosine-phosphatase	139
639001126	910	52.14	1	489	4	487	0.0e+00	533	COG1530	Ribonuclease G or E	487
639001127	314	38.25	1	281	1	275	2.0e-60	226	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
639001128	191	44.44	1	188	3	189	4.0e-50	191	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
639001130	176	29.94	1	173	1	175	2.0e-13	69.2	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
639001131	59	53.57	1	55	1	56	8.0e-11	58.7	COG0333	Ribosomal protein L32	57
639001132	343	50.6	4	332	1	331	6.0e-112	397	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
639001133	298	58.86	1	298	26	322	6.0e-105	374	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
639001134	318	51.31	8	312	3	308	1.0e-90	326	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
639001135	249	46.25	3	246	1	250	2.0e-43	169	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
639001136	79	67.95	1	78	3	80	1.0e-12	64.9	COG0236	Acyl carrier protein	80
639001137	414	57.91	4	412	3	410	0.0e+00	477	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
639001138	339	39.4	6	339	6	340	2.0e-93	335	COG1559	Cell division protein YceG, involved in septum cleavage	342
639001139	222	48.78	14	217	4	207	3.0e-53	201	COG0125	Thymidylate kinase	208
639001141	91	54.35	1	91	27	117	3.0e-29	120	COG3215	Tfp pilus assembly protein PilZ	117
639001142	381	29.68	1	376	8	405	6.0e-71	261	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
639001143	399	39.37	21	398	15	388	1.0e-82	300	COG1916	Pheromone shutdown protein TraB, contains GTxH motif (function unknown)	388
639001144	198	32.95	22	197	33	206	7.0e-26	110	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
639001146	441	22.44	73	439	26	406	2.0e-13	70.7	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
639001147	385	20.72	71	385	81	407	3.0e-17	83.4	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
639001148	202	54	2	200	21	220	3.0e-71	261	COG1136	ABC-type lipoprotein export system, ATPase component	226
639001149	411	27.33	21	298	10	292	2.0e-25	110	COG1566	Multidrug resistance efflux pump	352
639001150	234	28.49	20	202	11	193	3.0e-27	115	COG0518	GMP synthase - Glutamine amidotransferase domain	198
639001161	1468	37.94	11	855	8	788	0.0e+00	688	COG1201	Lhr-like helicase	814
639001162	283	46.18	6	279	2	274	4.0e-65	241	COG2890	Methylase of polypeptide chain release factors	280
639001164	419	51.65	21	408	1	393	0.0e+00	491	COG1219	ATP-dependent protease Clp, ATPase subunit	408
639001165	357	56.98	7	349	6	347	0.0e+00	507	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
639001166	143	59.32	24	141	1	118	3.0e-26	111	COG1734	RNA polymerase-binding transcription factor DksA	120
639001167	362	62.81	1	361	1	363	0.0e+00	513	COG0216	Protein chain release factor A	363
639001168	422	49.52	1	414	3	411	5.0e-123	434	COG0373	Glutamyl-tRNA reductase	414
639001170	201	25.53	12	197	17	203	4.0e-23	101	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
639001171	289	46.53	1	275	1	288	3.0e-82	298	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
639001173	312	57.37	1	310	5	313	3.0e-113	401	COG0462	Phosphoribosylpyrophosphate synthetase	314
639001174	233	41.05	4	98	1	93	8.0e-18	84.2	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
639001175	202	45.79	7	196	1	190	3.0e-66	245	COG0193	Peptidyl-tRNA hydrolase	190
639001176	363	59.68	1	363	1	372	0.0e+00	497	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
639001181	161	25.93	1	148	8	169	5.0e-09	53.9	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
639001184	129	54.76	4	129	1	126	2.0e-43	167	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
639001188	122	39	5	104	3	89	3.0e-10	57.5	COG5556	Uncharacterized protein	110
639001190	126	35.43	2	126	4	130	3.0e-17	80.9	COG4374	PIN domain nuclease, a component of toxin-antitoxin system (PIN domain)	130
639001191	412	24.64	1	341	2	302	1.0e-27	117	COG3535	Uncharacterized conserved protein, DUF917 family	357
639001195	386	40.62	8	385	5	345	4.0e-90	325	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
639001196	421	46.57	18	419	40	445	1.0e-122	433	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
639001197	480	44.44	13	476	4	465	5.0e-128	451	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
639001198	473	36.86	7	465	3	474	1.0e-108	387	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
639001199	324	32.91	5	318	1	314	2.0e-57	215	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
639001200	403	39.9	21	402	3	393	1.0e-94	340	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
639001201	522	29.51	232	514	1	271	1.0e-30	127	COG0388	Predicted amidohydrolase	274
639001202	132	28.33	5	124	1	115	1.0e-12	65.4	COG1734	RNA polymerase-binding transcription factor DksA	120
639001206	97	49.48	1	97	4	98	8.0e-24	101	COG3636	DNA-binding prophage protein	100
639001207	98	53.06	1	98	3	100	2.0e-27	114	COG3657	Putative component of the toxin-antitoxin plasmid stabilization module	100
639001210	93	43.62	1	93	1	94	2.0e-22	96.9	COG3549	Plasmid maintenance system killer protein	94
639001211	100	48.89	4	92	7	94	1.0e-21	94.6	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
639001214	81	39.74	4	81	3	80	8.0e-13	65.1	COG5302	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid	80
639001217	96	48.89	7	94	2	91	2.0e-17	80.3	COG2929	Uncharacterized conserved protein, DUF497 family	93
639001219	226	29.65	33	204	25	188	8.0e-26	110	COG3271	Predicted double-glycine peptidase	201
639001223	451	43.27	25	450	27	464	1.0e-109	390	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
639001224	345	35.32	103	320	9	215	2.0e-47	183	COG0543	NAD(P)H-flavin reductase	252
639001224	345	37.11	1	92	3	99	4.0e-13	69.3	COG0633	Ferredoxin	102
639001225	273	40.73	8	249	3	248	1.0e-63	236	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
639001226	295	45.35	26	293	23	286	3.0e-75	275	COG3001	Fructosamine-3-kinase	286
639001227	193	26.03	2	147	3	133	5.0e-14	71.1	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
639001228	370	48.73	2	355	5	356	1.0e-97	350	COG3288	NAD/NADP transhydrogenase alpha subunit	356
639001230	490	41.94	1	487	2	463	7.0e-122	431	COG1282	NAD/NADP transhydrogenase beta subunit	463
639001234	367	27.75	8	366	1	364	1.0e-33	137	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
639001235	358	26.04	1	349	1	361	1.0e-32	134	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
639001238	566	29.51	17	549	32	531	1.0e-74	274	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
639001239	306	28.18	5	302	3	303	2.0e-28	120	COG0451	Nucleoside-diphosphate-sugar epimerase	314
639001241	404	40.21	4	389	1	387	7.0e-98	351	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
639001242	202	26.24	43	183	40	160	6.0e-14	70.8	COG4731	Uncharacterized conserved protein, DUF2147 family	162
639001243	734	47.48	5	733	1	730	0.0e+00	751	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
639001244	223	18.94	1	220	40	260	2.0e-14	72.8	COG3087	Cell division protein FtsN	264
639001245	345	19.87	15	325	22	310	7.0e-06	45	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
639001246	294	45.42	1	281	1	284	5.0e-69	254	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
639001247	639	54.55	5	627	26	651	0.0e+00	781	COG1166	Arginine decarboxylase (spermidine biosynthesis)	652
639001248	285	40.79	5	278	3	275	1.0e-70	259	COG0421	Spermidine synthase	282
639001249	268	36.78	1	261	1	256	4.0e-44	171	COG0390	ABC-type iron transport system FetAB, permease component	256
639001250	200	32.21	1	186	1	206	2.0e-27	115	COG1131	ABC-type multidrug transport system, ATPase component	293
639001251	428	58.72	24	428	2	404	5.0e-114	404	COG0004	Ammonia channel protein AmtB	409
639001252	112	64.29	1	112	1	112	6.0e-38	149	COG0347	Nitrogen regulatory protein PII	112
639001254	115	34.52	1	84	10	93	2.0e-13	67.3	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
639001255	500	58.76	15	493	1	485	0.0e+00	586	COG0606	Predicted ATPase with chaperone activity	490
639001256	423	27.71	1	421	5	383	2.0e-32	133	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
639001260	366	29.33	7	364	24	397	2.0e-54	206	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
639001261	151	23.91	30	120	17	108	3.0e-08	51.2	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
639001262	194	25	1	128	3	134	3.0e-08	51.8	COG1225	Peroxiredoxin	157
639001263	366	38.22	41	343	10	279	5.0e-50	192	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
639001264	310	42.19	1	301	1	301	2.0e-80	292	COG2974	DNA recombination-dependent growth factor C	303
639001266	406	25.2	251	369	2	118	5.0e-09	55.8	COG3597	Uncharacterized conserved protein, DUF697 family	139
639001268	178	46.51	52	178	2	129	7.0e-47	180	COG0229	Peptide methionine sulfoxide reductase MsrB	140
639001269	345	29.11	1	335	1	346	9.0e-56	210	COG1253	Hemolysin or related protein, contains CBS domains	429
639001270	372	43.83	2	372	25	398	7.0e-89	320	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
639001272	149	22.76	28	148	8	124	2.0e-07	48.6	COG3293	Transposase	124
639001274	477	21.85	53	377	23	273	2.0e-10	61.1	COG1566	Multidrug resistance efflux pump	352
639001275	462	23.89	97	450	92	444	2.0e-23	104	COG1538	Outer membrane protein TolC	457
639001276	558	22.88	9	549	129	672	7.0e-44	172	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
639001277	192	25.49	48	191	14	162	2.0e-13	68.9	COG4731	Uncharacterized conserved protein, DUF2147 family	162
639001281	416	31.71	1	416	2	451	3.0e-56	212	COG1070	Sugar (pentulose or hexulose) kinase	502
639001283	443	29.86	1	419	26	446	3.0e-54	206	COG0534	Na+-driven multidrug efflux pump	455
639001290	149	22.48	22	148	2	124	2.0e-07	48.6	COG3293	Transposase	124
639001298	174	28.32	4	174	3	166	9.0e-17	80.2	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
639001304	188	38.02	5	125	3	110	1.0e-13	69.8	COG5556	Uncharacterized protein	110
639001309	609	58.5	304	607	38	342	2.0e-96	347	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
639001310	581	40.48	4	574	1	556	4.0e-120	425	COG0358	DNA primase (bacterial type)	568
639001311	150	54.73	2	148	1	148	2.0e-36	145	COG1610	Uncharacterized conserved protein YqeY	148
639001313	347	54.68	7	344	1	340	4.0e-124	438	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
639001314	198	43.22	4	197	2	200	2.0e-39	155	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
639001315	120	41.53	1	117	2	119	2.0e-26	111	COG1539	Dihydroneopterin aldolase	121
639001316	163	41.29	1	151	1	153	2.0e-28	118	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
639001317	362	39.89	1	344	24	367	9.0e-77	280	COG1565	SAM-dependent methyltransferase, MidA family	370
639001318	368	31.49	125	359	1	221	9.0e-30	124	COG2114	Adenylate cyclase, class 3	227
639001319	263	39.7	1	263	4	268	3.0e-53	201	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
639001320	410	37.56	1	388	23	402	2.0e-70	260	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
639001321	319	24.91	6	253	3	275	7.0e-19	88.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
639001322	95	63.64	6	93	5	92	6.0e-22	95.5	COG3461	Uncharacterized protein	103
639001323	266	32.09	1	263	4	253	1.0e-09	56.9	COG0730	Uncharacterized membrane protein YfcA	258
639001327	95	21.21	14	79	3	67	2.0e-06	44.1	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
639001328	678	37.07	570	677	8	123	3.0e-22	100	COG0073	tRNA-binding EMAP/Myf domain	123
639001328	678	41.5	1	545	3	558	0.0e+00	639	COG0143	Methionyl-tRNA synthetase	558
639001329	277	55.83	12	173	10	172	3.0e-50	192	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
639001330	214	56.25	1	208	1	208	1.0e-79	289	COG0177	Endonuclease III	211
639001332	104	42.86	3	97	11	108	1.0e-21	94.7	COG3785	Heat shock protein HspQ	116
639001336	454	31.88	13	453	4	443	2.0e-94	339	COG0174	Glutamine synthetase	443
639001337	467	39.18	7	465	13	468	1.0e-105	376	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
639001338	417	40.42	35	412	1	376	1.0e-101	363	COG1454	Alcohol dehydrogenase, class IV	377
639001339	84	28.33	4	63	6	64	6.0e-07	45.7	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
639001346	222	38.1	14	118	10	109	6.0e-14	71.2	COG2863	Cytochrome c553	121
639001347	330	37.54	43	323	2	293	9.0e-68	250	COG3258	Cytochrome c	293
639001351	133	41.35	1	103	1	104	2.0e-17	81.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
639001352	461	45.04	2	459	1	483	0.0e+00	519	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
639001354	875	21.8	10	353	2	239	7.0e-25	109	COG0176	Transaldolase	239
639001354	875	24.68	406	738	41	431	1.0e-29	125	COG0166	Glucose-6-phosphate isomerase	446
639001360	612	18.46	144	542	22	425	5.0e-16	80	COG5421	Transposase	480
639001361	610	17.93	144	543	22	428	2.0e-10	61.1	COG5421	Transposase	480
639001365	215	21.74	37	196	24	174	3.0e-13	68.8	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
639001366	225	22.79	1	200	6	206	1.0e-14	73.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
639001374	302	30.87	2	215	61	290	3.0e-25	108	COG0790	TPR repeat	292
639001393	209	52.02	1	198	1	198	3.0e-59	221	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
639001395	234	42.08	3	204	1	202	2.0e-45	175	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
639001397	408	55.75	1	391	5	390	2.0e-114	406	COG3004	Na+/H+ antiporter NhaA	390
639001398	595	60.91	1	588	1	585	0.0e+00	885	COG0173	Aspartyl-tRNA synthetase	585
639001399	103	33.33	2	61	23	81	5.0e-08	49.7	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
639001400	295	39.82	81	295	16	235	6.0e-37	148	COG4089	Uncharacterized membrane protein	235
639001401	287	29.26	10	272	6	250	1.0e-37	150	COG0300	Short-chain dehydrogenase	265
639001405	366	34.84	1	366	5	372	9.0e-82	297	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
639001408	481	24.43	1	469	3	480	2.0e-12	67.4	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
639001409	280	14.55	2	269	27	286	5.0e-07	48.6	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
639001410	546	20.94	131	494	69	429	5.0e-23	103	COG5421	Transposase	480
639001411	418	18.35	47	407	2	380	6.0e-10	58.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639001414	380	27.36	1	312	2	309	4.0e-32	132	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
639001415	742	27.59	39	497	13	458	4.0e-48	186	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
639001415	742	29.71	510	742	9	245	9.0e-28	119	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
639001416	364	25.65	12	358	5	301	4.0e-38	152	COG1216	Glycosyltransferase, GT2 family	305
639001419	278	21.15	17	268	1	259	3.0e-20	92.5	COG1216	Glycosyltransferase, GT2 family	305
639001420	390	18.23	1	347	3	343	4.0e-14	72.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639001423	260	33.69	1	182	22	205	2.0e-26	112	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
639001424	308	27.46	1	262	6	294	2.0e-31	130	COG3621	Patatin-like phospholipase/acyl hydrolase	394
639001425	660	26.8	412	657	3	221	1.0e-15	79.1	COG0569	Trk K+ transport system, NAD-binding component	225
639001425	660	43.98	1	376	5	378	4.0e-63	236	COG0475	Kef-type K+ transport system, membrane component KefB	397
639001430	311	31.66	56	307	8	257	8.0e-34	138	COG2116	Formate/nitrite transporter FocA, FNT family	265
639001431	866	55.31	5	857	1	782	0.0e+00	949	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
639001432	250	50.61	7	246	3	247	2.0e-69	256	COG1496	Copper oxidase (laccase) domain	249
639001433	315	43.85	6	301	1	288	1.0e-75	276	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
639001434	251	38.46	4	250	7	243	1.0e-51	197	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
639001435	112	73.21	1	112	1	112	6.0e-40	155	COG0347	Nitrogen regulatory protein PII	112
639001436	543	29.39	5	243	3	244	6.0e-34	139	COG0388	Predicted amidohydrolase	274
639001436	543	39.3	257	532	1	268	2.0e-66	247	COG0171	NH3-dependent NAD+ synthetase	268
639001437	290	65.51	1	286	1	287	2.0e-111	395	COG0074	Succinyl-CoA synthetase, alpha subunit	293
639001438	389	60	1	388	1	385	0.0e+00	502	COG0045	Succinyl-CoA synthetase, beta subunit	387
639001439	528	22.88	210	520	17	327	3.0e-27	116	COG0642	Signal transduction histidine kinase	336
639001440	445	48	7	445	8	457	0.0e+00	464	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
639001441	144	33.33	2	133	1	122	7.0e-16	76.5	COG4969	Tfp pilus assembly protein, major pilin PilA	125
639001444	74	27.63	1	74	2	77	1.0e-06	44.7	COG3668	Plasmid stabilization system protein ParE	98
639001446	307	22.38	20	290	7	278	4.0e-16	79	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
639001449	208	36.17	5	189	3	186	9.0e-34	136	COG3658	Cytochrome b	192
639001451	224	43.91	1	221	1	228	8.0e-53	200	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
639001452	449	27.38	123	449	3	336	2.0e-25	111	COG0642	Signal transduction histidine kinase	336
639001454	317	28.91	63	315	1	228	4.0e-19	89.1	COG3039	Transposase and inactivated derivatives, IS5 family	230
639001456	290	54.39	6	290	4	287	2.0e-108	385	COG0788	Formyltetrahydrofolate hydrolase	287
639001458	554	46.78	3	537	1	530	0.0e+00	563	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
639001459	301	32.39	1	292	1	317	1.0e-57	216	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
639001460	165	39.71	15	148	25	159	1.0e-24	105	COG4067	Uncharacterized conserved protein	162
639001461	187	35.86	28	164	7	150	3.0e-22	98.5	COG1656	Uncharacterized conserved protein, contains PIN domain	165
639001462	420	67.63	3	416	2	412	0.0e+00	662	COG0112	Glycine/serine hydroxymethyltransferase	413
639001464	167	58.97	1	156	1	156	1.0e-50	191	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
639001465	376	40.54	155	375	1	218	3.0e-50	192	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
639001465	376	58.22	9	154	1	146	9.0e-56	210	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
639001466	206	49.74	1	194	1	192	9.0e-65	239	COG0307	Riboflavin synthase alpha chain	204
639001467	377	38.64	204	376	2	174	2.0e-37	150	COG0807	GTP cyclohydrolase II	193
639001467	377	55.67	1	203	2	203	2.0e-76	279	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
639001468	155	59.21	2	153	1	152	2.0e-52	198	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
639001469	157	43.18	14	138	10	141	7.0e-29	120	COG0781	Transcription termination factor NusB	151
639001470	324	45.03	1	319	1	317	5.0e-73	268	COG0611	Thiamine monophosphate kinase	317
639001472	183	37.14	77	181	8	109	2.0e-22	99.2	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
639001473	1233	58.2	8	327	8	311	1.0e-109	392	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
639001473	1233	60.07	328	1195	1	842	0.0e+00	1136	COG1410	Methionine synthase I, cobalamin-binding domain	842
639001478	517	53.09	1	239	7	249	9.0e-66	244	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
639001481	1036	43.32	321	1031	1	708	0.0e+00	709	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
639001482	250	25.97	3	244	37	290	8.0e-09	54.3	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
639001483	461	22.22	33	397	15	287	8.0e-12	65.4	COG1566	Multidrug resistance efflux pump	352
639001485	465	34.26	34	462	25	454	7.0e-53	201	COG1538	Outer membrane protein TolC	457
639001488	259	24.22	3	253	1	239	6.0e-31	127	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
639001489	327	24.57	29	310	5	280	1.0e-17	84.4	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
639001494	234	29.29	10	232	12	238	1.0e-28	119	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
639001497	228	48.47	3	227	2	228	7.0e-63	233	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
639001498	186	34.75	24	161	20	158	4.0e-31	127	COG4067	Uncharacterized conserved protein	162
639001499	299	27.9	26	299	46	304	1.0e-35	143	COG4313	Uncharacterized conserved protein	304
639001502	363	34.85	16	343	4	323	2.0e-56	213	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
639001503	1627	48.96	27	1608	25	1592	0.0e+00	1664	COG2902	NAD-specific glutamate dehydrogenase	1592
639001504	265	32.71	14	260	17	281	3.0e-23	102	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
639001505	762	43.03	433	753	5	324	1.0e-92	334	COG0280	Phosphotransacetylase	327
639001505	762	54.48	1	432	13	432	0.0e+00	550	COG0281	Malic enzyme	432
639001506	331	50.46	8	329	6	320	2.0e-103	369	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
639001509	237	60.89	13	237	12	236	4.0e-73	267	COG3826	Uncharacterized protein	236
639001510	263	33.57	13	262	1	272	7.0e-29	120	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
639001511	205	37.72	36	199	4	168	3.0e-37	148	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
639001512	338	52.06	5	317	2	304	1.0e-89	323	COG0492	Thioredoxin reductase	305
639001513	200	54.08	1	196	1	194	8.0e-72	263	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
639001517	231	49.07	10	223	1	212	1.0e-54	206	COG1515	Deoxyinosine 3'endonuclease (endonuclease V)	212
639001519	602	35	3	598	2	606	3.0e-106	379	COG4206	Outer membrane cobalamin receptor protein	608
639001520	233	42.67	12	233	1	225	5.0e-59	220	COG0220	tRNA G46 methylase TrmB	227
639001521	260	61.15	1	260	3	260	2.0e-100	358	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
639001522	67	38.81	1	67	2	68	3.0e-12	63.7	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
639001524	652	33.7	28	652	14	649	6.0e-124	438	COG2766	Predicted Ser/Thr protein kinase	649
639001525	391	27.05	21	388	14	422	1.0e-56	214	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
639001526	458	28.96	2	447	12	480	3.0e-71	262	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
639001531	700	21.56	2	637	9	611	1.0e-43	172	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
639001532	363	46.44	8	356	1	338	8.0e-100	357	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
639001533	81	55.7	2	80	9	87	5.0e-24	102	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
639001534	341	24.02	18	271	6	228	6.0e-19	88.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
639001538	317	28.91	63	315	1	228	2.0e-19	89.8	COG3039	Transposase and inactivated derivatives, IS5 family	230
639001551	367	46.87	1	363	1	363	2.0e-107	382	COG1980	Archaeal fructose 1,6-bisphosphatase	369
639001553	219	31.63	2	213	1	209	2.0e-31	129	COG0625	Glutathione S-transferase	211
639001554	328	23.05	45	326	32	266	9.0e-36	144	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
639001556	565	25.53	26	401	3	377	7.0e-49	189	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
639001557	323	20	44	247	30	232	9.0e-14	71	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
639001559	437	59.16	7	437	2	427	0.0e+00	514	COG3508	Homogentisate 1,2-dioxygenase	427
639001560	307	37.59	19	306	4	286	2.0e-59	222	COG3327	DNA-binding transcriptional regulator PaaX (phenylacetic acid degradation)	291
639001566	409	27.23	4	380	3	359	3.0e-43	169	COG4637	Predicted ATPase	373
639001575	330	45.32	31	296	1	265	1.0e-85	310	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
639001576	93	59	4	93	10	109	1.0e-28	117	COG3460	1,2-phenylacetyl-CoA epoxidase, PaaB subunit	117
639001577	252	36.61	2	252	15	265	1.0e-52	199	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
639001578	172	31.73	7	107	6	108	5.0e-15	74.2	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
639001579	379	30.74	21	289	1	254	5.0e-44	172	COG1018	Ferredoxin-NADP reductase	266
639001579	379	31.33	293	370	7	89	4.0e-11	62.8	COG0633	Ferredoxin	102
639001584	353	32.84	79	278	36	232	9.0e-28	118	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
639001585	292	28.78	1	135	2	140	4.0e-06	46	COG2510	Uncharacterized membrane protein	140
639001586	71	57.97	3	71	1	69	5.0e-13	65.7	COG3585	Molybdopterin-binding protein	69
639001587	255	28.05	2	243	17	258	1.0e-41	163	COG0725	ABC-type molybdate transport system, periplasmic component	258
639001588	261	46.12	3	258	2	257	1.0e-56	213	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
639001589	555	23.15	86	523	35	435	7.0e-33	135	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
639001590	263	40.61	1	260	2	257	2.0e-53	203	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
639001591	505	49.31	9	296	5	292	1.0e-86	314	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
639001592	154	35.29	29	143	21	138	2.0e-17	81.6	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
639001593	402	43.69	1	402	1	392	7.0e-88	317	COG0183	Acetyl-CoA acetyltransferase	392
639001596	474	41.48	276	449	1	174	9.0e-36	144	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
639001597	280	29.17	35	274	1	259	2.0e-40	159	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
639001599	211	42.28	2	123	1	121	5.0e-23	101	COG2863	Cytochrome c553	121
639001600	254	50.78	46	237	4	196	6.0e-65	240	COG0218	GTP-binding protein EngB required for normal cell division	200
639001601	898	57.31	298	898	1	593	0.0e+00	774	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
639001602	244	37.13	39	235	4	205	1.0e-43	170	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
639001604	736	46.3	19	667	1	655	0.0e+00	597	COG0210	Superfamily I DNA or RNA helicase	655
639001605	315	35.59	4	296	1	288	4.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
639001606	304	31.3	46	286	58	298	2.0e-33	136	COG1560	Lauroyl/myristoyl acyltransferase	308
639001610	606	55.54	3	606	8	597	0.0e+00	762	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
639001611	456	54.03	1	453	2	460	0.0e+00	607	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
639001612	141	50.38	4	135	3	135	7.0e-30	123	COG0355	FoF1-type ATP synthase, epsilon subunit	135
639001613	465	75	1	465	1	465	0.0e+00	798	COG0055	FoF1-type ATP synthase, beta subunit	468
639001614	286	51.05	5	286	1	286	3.0e-95	341	COG0224	FoF1-type ATP synthase, gamma subunit	287
639001615	514	65.56	4	514	3	502	0.0e+00	800	COG0056	FoF1-type ATP synthase, alpha subunit	504
639001616	153	34.21	2	152	26	177	2.0e-29	121	COG0712	FoF1-type ATP synthase, delta subunit	178
639001617	154	37.09	4	154	8	158	6.0e-17	80.3	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
639001618	99	40.58	17	85	11	79	2.0e-07	47.1	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
639001619	261	33.86	8	255	6	243	1.0e-38	153	COG0356	FoF1-type ATP synthase, membrane subunit a	246
639001621	289	41.57	32	284	1	240	3.0e-30	125	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
639001622	262	44.88	1	252	1	253	4.0e-60	225	COG1192	Cellulose biosynthesis protein BcsQ	259
639001623	203	45.26	13	194	22	211	3.0e-46	178	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
639001624	548	42.81	251	546	6	309	5.0e-67	249	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
639001625	82	57.33	7	81	5	79	5.0e-26	109	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
639001627	313	37.54	13	313	1	297	1.0e-55	210	COG2177	Cell division protein FtsX	297
639001628	226	61.47	1	218	1	218	7.0e-83	300	COG2884	ABC-type ATPase involved in cell division	223
639001629	357	54.22	29	348	10	340	2.0e-109	389	COG0552	Signal recognition particle GTPase	340
639001630	467	33.33	34	453	16	433	1.0e-78	287	COG0612	Predicted Zn-dependent peptidase	438
639001631	443	26.54	12	440	3	437	9.0e-65	241	COG0612	Predicted Zn-dependent peptidase	438
639001632	194	45.45	6	187	1	187	3.0e-51	195	COG0742	16S rRNA G966 N2-methylase RsmD	187
639001633	163	57.14	1	161	1	159	1.0e-59	222	COG0669	Phosphopantetheine adenylyltransferase	159
639001634	573	46.25	33	562	16	538	0.0e+00	532	COG0405	Gamma-glutamyltranspeptidase	539
639001635	548	48.82	1	533	1	523	0.0e+00	502	COG0459	Chaperonin GroEL (HSP60 family)	524
639001636	96	59.38	1	96	1	96	6.0e-31	125	COG0234	Co-chaperonin GroES (HSP10)	96
639001637	110	48.54	4	106	1	103	5.0e-29	119	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
639001638	618	43.49	28	610	16	565	3.0e-127	449	COG4232	Thiol:disulfide interchange protein	569
639001639	173	30.46	34	172	6	152	8.0e-16	76.8	COG1225	Peroxiredoxin	157
639001642	147	53.42	2	147	1	145	3.0e-52	197	COG0757	3-dehydroquinate dehydratase	146
639001643	151	44.52	6	151	1	139	4.0e-27	114	COG0511	Biotin carboxyl carrier protein	140
639001644	447	65.25	1	444	1	445	0.0e+00	613	COG0439	Biotin carboxylase	449
639001646	317	29.3	63	315	1	228	1.0e-19	90.6	COG3039	Transposase and inactivated derivatives, IS5 family	230
639001647	465	42.01	48	446	29	401	2.0e-97	350	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
639001656	317	29.3	63	315	1	228	2.0e-19	90.2	COG3039	Transposase and inactivated derivatives, IS5 family	230
639001657	281	34.92	3	125	4	120	1.0e-14	74.2	COG2105	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family	120
639001660	624	28.7	4	216	3	197	2.0e-18	87.5	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
639001666	485	51.55	1	483	7	489	0.0e+00	606	COG0753	Catalase	496
639001667	591	52.98	125	574	4	454	0.0e+00	502	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
639001668	441	41.59	3	441	1	403	6.0e-105	374	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
639001669	892	67.01	13	891	8	886	0.0e+00	1341	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
639001670	482	41.58	11	478	3	451	4.0e-113	402	COG2079	2-methylcitrate dehydratase PrpD	453
639001671	374	48.13	8	373	18	390	4.0e-119	421	COG0372	Citrate synthase	390
639001672	293	60.14	5	290	4	288	4.0e-89	321	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
639001676	422	22.41	1	351	46	385	5.0e-20	92.7	COG2865	Predicted transcriptional regulator, contains HTH domain	467
639001681	473	45.36	1	461	1	454	0.0e+00	487	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
639001682	443	45.72	1	442	1	404	2.0e-115	409	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
639001683	940	56.99	5	940	1	905	0.0e+00	1244	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
639001684	258	48.43	7	257	1	254	3.0e-56	211	COG0805	Sec-independent protein secretion pathway component TatC	255
639001685	109	34.25	1	73	1	73	2.0e-14	70.8	COG1826	Sec-independent protein translocase protein TatA	94
639001686	88	33.33	4	81	2	79	2.0e-11	60.7	COG1826	Sec-independent protein translocase protein TatA	94
639001687	114	49.45	5	95	1	91	9.0e-25	105	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
639001688	129	65.38	1	104	3	106	2.0e-44	170	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
639001689	257	67.45	2	256	1	254	9.0e-107	379	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
639001690	246	47.3	1	241	2	239	9.0e-71	260	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
639001691	215	49.05	1	209	1	204	2.0e-73	268	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
639001692	197	58.88	1	197	1	195	8.0e-79	286	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
639001693	149	46.9	1	145	1	145	2.0e-47	181	COG1490	D-Tyr-tRNAtyr deacylase	145
639001696	482	42.54	1	482	1	488	3.0e-92	333	COG0168	Trk-type K+ transport system, membrane component	499
639001697	458	38.53	1	229	1	225	8.0e-45	175	COG0569	Trk K+ transport system, NAD-binding component	225
639001698	448	40.04	1	446	2	460	1.0e-113	403	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
639001699	740	32.72	22	721	16	709	5.0e-115	409	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
639001701	423	38.7	83	422	1	353	5.0e-81	295	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
639001702	314	53.16	7	307	4	303	8.0e-101	360	COG0223	Methionyl-tRNA formyltransferase	307
639001703	177	54.17	1	164	1	168	6.0e-57	213	COG0242	Peptide deformylase	168
639001705	371	43.65	6	367	2	350	7.0e-102	364	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
639001706	157	49.68	5	157	1	157	1.0e-37	149	COG2922	Uncharacterized conserved protein Smg, DUF494 family	157
639001707	774	47.77	3	579	1	559	0.0e+00	623	COG0550	DNA topoisomerase IA	570
639001708	188	41.01	14	188	20	196	3.0e-40	158	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
639001709	307	64.24	3	303	4	303	5.0e-129	454	COG0408	Coproporphyrinogen III oxidase	303
639001710	260	27.66	67	254	2	174	1.0e-20	93.9	COG1076	DnaJ-domain-containing proteins 1	174
639001711	471	25.52	47	471	10	421	2.0e-32	133	COG5316	Uncharacterized protein	421
639001714	361	25.61	20	303	15	262	4.0e-26	112	COG1562	Phytoene/squalene synthetase	288
639001715	652	31.84	112	643	3	510	1.0e-64	241	COG1657	Squalene cyclase	517
639001717	649	61.22	4	619	3	626	0.0e+00	908	COG1154	Deoxyxylulose-5-phosphate synthase	627
639001718	306	59.04	1	292	2	294	1.0e-110	393	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
639001719	385	27.92	22	315	13	316	3.0e-23	103	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
639001720	373	18.44	4	360	12	394	5.0e-13	68.8	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
639001722	759	53.52	1	754	6	769	0.0e+00	894	COG2183	Transcriptional accessory protein Tex/SPT6	780
639001723	378	34.68	24	369	19	355	5.0e-39	155	COG0628	Predicted PurR-regulated permease PerM	355
639001725	439	27.6	249	439	53	243	4.0e-28	119	COG1360	Flagellar motor protein MotB	244
639001726	166	19.14	20	166	49	209	4.0e-07	47.6	COG2945	Alpha/beta superfamily hydrolase	210
639001728	123	69.83	5	120	9	124	1.0e-44	171	COG3651	Uncharacterized conserved protein, DUF2237 family	125
639001729	764	24.63	44	374	13	331	4.0e-33	136	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
639001729	764	34.03	429	760	8	324	9.0e-55	208	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
639001731	140	25.93	1	135	2	131	1.0e-13	69.4	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
639001735	139	30.94	1	139	3	132	3.0e-13	67.9	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
639001736	84	48.68	1	76	1	76	3.0e-13	67	COG4691	Plasmid stability protein	80
639001746	415	20.41	80	415	3	336	1.0e-19	91.4	COG0642	Signal transduction histidine kinase	336
639001747	179	60.11	1	178	5	182	2.0e-57	215	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
639001749	414	20.45	13	345	1	332	9.0e-26	111	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
639001750	199	22.17	3	164	51	249	3.0e-14	71.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
639001751	589	34.13	11	554	3	525	4.0e-87	316	COG0659	Sulfate permease or related transporter, MFS superfamily	554
639001752	452	48.48	1	449	1	462	0.0e+00	499	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
639001754	485	30.75	150	482	11	336	2.0e-38	154	COG0642	Signal transduction histidine kinase	336
639001755	347	67.07	5	335	2	332	0.0e+00	527	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
639001756	203	43.56	1	200	1	201	3.0e-54	205	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
639001757	173	56.33	11	167	1	158	6.0e-51	193	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
639001758	247	60.74	1	241	1	241	8.0e-95	340	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
639001759	420	23.66	203	420	50	262	1.0e-05	45	COG3137	Putative salt-induced outer membrane protein YdiY	262
639001762	406	29.07	135	383	12	267	3.0e-31	129	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
639001763	163	39.16	5	138	10	152	3.0e-32	131	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
639001764	248	43.37	1	242	3	248	1.0e-46	180	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
639001766	221	32.98	1	190	1	191	4.0e-40	157	COG3124	Acyl carrier protein phosphodiesterase	193
639001767	162	33.59	32	157	7	131	3.0e-23	101	COG0824	Acyl-CoA thioesterase FadM	137
639001768	437	40.87	1	433	21	453	4.0e-107	381	COG0513	Superfamily II DNA and RNA helicase	513
639001769	108	59.05	1	104	1	105	4.0e-41	159	COG0278	Glutaredoxin-related protein	105
639001771	222	27.11	19	217	4	228	1.0e-15	76.4	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
639001772	344	61.52	1	342	1	343	0.0e+00	488	COG0418	Dihydroorotase	344
639001773	404	58.13	1	404	1	400	0.0e+00	585	COG0137	Argininosuccinate synthase	403
639001775	513	35.48	8	294	1	308	3.0e-67	249	COG3854	Stage III sporulation protein SpoIIIAA	308
639001776	457	42.08	1	449	18	477	2.0e-122	432	COG0380	Trehalose-6-phosphate synthase	486
639001777	590	28.45	4	583	18	605	1.0e-74	274	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
639001779	212	32.68	9	212	11	214	5.0e-37	147	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
639001780	327	41.53	60	241	1	135	1.0e-35	143	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
639001781	214	40.29	9	214	1	204	2.0e-46	179	COG2941	Demethoxyubiquinone hydroxylase, CLK1/Coq7/Cat5 family	204
639001782	142	62.24	1	142	1	143	1.0e-52	198	COG0102	Ribosomal protein L13	148
639001783	130	63.85	1	130	1	130	7.0e-45	172	COG0103	Ribosomal protein S9	130
639001788	439	31.75	35	382	24	371	4.0e-44	172	COG5659	SRSO17 transposase	385
639001792	787	47.5	82	770	6	696	0.0e+00	743	COG0855	Polyphosphate kinase	696
639001793	515	32.4	207	454	1	245	1.0e-23	105	COG5607	CHAD domain (function unknown)	283
639001794	514	41.92	21	503	1	488	3.0e-110	392	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
639001797	178	35.76	11	175	2	159	5.0e-29	120	COG2062	Phosphohistidine phosphatase SixA	163
639001798	255	47.89	1	255	9	267	3.0e-67	248	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
639001799	610	33.44	5	589	16	604	1.0e-109	390	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
639001800	664	18.76	233	662	160	573	4.0e-15	77	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
639001801	729	43.72	8	553	6	549	0.0e+00	576	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
639001803	371	39.39	1	357	1	358	4.0e-100	358	COG5351	Uncharacterized protein	367
639001804	348	18.84	7	307	33	356	2.0e-21	97.3	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
639001808	345	29.97	11	337	11	341	2.0e-18	87.1	COG3515	Predicted component of the type VI protein secretion system	346
639001809	163	50	2	146	17	162	1.0e-40	158	COG3516	Predicted component of the type VI protein secretion system	169
639001810	500	60.89	4	499	3	495	0.0e+00	755	COG3517	Predicted component of the type VI protein secretion system	495
639001811	159	34.9	1	141	2	150	2.0e-26	111	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
639001812	263	43.17	122	259	23	157	3.0e-20	92.7	COG3518	Predicted component of the type VI protein secretion system	157
639001813	625	44.98	1	625	1	621	0.0e+00	600	COG3519	Type VI protein secretion system component VasA	621
639001814	360	42.14	2	315	10	325	2.0e-66	246	COG3520	Predicted component of the type VI protein secretion system	335
639001815	915	38.9	12	914	1	783	0.0e+00	748	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
639001817	476	25	1	464	1	428	1.0e-50	194	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
639001818	183	24.32	9	156	7	135	2.0e-15	75.7	COG3521	Predicted component of the type VI protein secretion system	159
639001819	448	48.55	1	445	1	446	1.0e-130	460	COG3522	Predicted component of the type VI protein secretion system	446
639001820	435	29.5	290	427	53	186	7.0e-15	75.6	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
639001820	435	40.31	17	274	1	258	2.0e-54	206	COG3455	Type VI protein secretion system component VasF	262
639001821	1157	36.01	1	1157	5	1187	0.0e+00	779	COG3523	Type VI protein secretion system component VasK	1188
639001822	502	30.43	7	236	8	220	4.0e-29	122	COG3913	Uncharacterized protein	227
639001822	502	31.37	255	497	1	253	8.0e-45	175	COG0631	Serine/threonine protein phosphatase PrpC	262
639001823	605	22.92	180	499	2	326	7.0e-37	149	COG0515	Serine/threonine protein kinase	384
639001828	1215	43	9	684	1	674	0.0e+00	581	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
639001828	1215	53.28	697	1211	2	528	0.0e+00	680	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
639001829	1032	37.51	2	1005	1	1008	0.0e+00	839	COG0841	Multidrug efflux pump subunit AcrB	1009
639001830	367	30.13	1	354	5	368	5.0e-26	112	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
639001831	419	35.08	35	415	13	339	3.0e-48	186	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
639001832	270	40.73	1	269	5	278	2.0e-63	235	COG0169	Shikimate 5-dehydrogenase	283
639001833	324	59.13	1	323	10	330	0.0e+00	495	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
639001834	160	25.93	13	137	1	135	3.0e-07	48.1	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
639001835	337	52.6	2	327	25	349	3.0e-115	408	COG0407	Uroporphyrinogen-III decarboxylase	352
639001836	469	45.49	23	467	1	450	0.0e+00	461	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
639001837	1462	59.47	674	1155	1	485	0.0e+00	647	COG0069	Glutamate synthase domain 2	485
639001840	332	24.08	47	326	4	301	6.0e-22	98.3	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
639001841	309	41.35	1	302	9	320	2.0e-60	226	COG0714	MoxR-like ATPase	329
639001843	231	20	37	230	13	195	1.0e-11	63.8	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
639001846	485	37.19	33	473	33	471	5.0e-91	328	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
639001847	373	31.01	17	360	16	355	9.0e-38	151	COG0628	Predicted PurR-regulated permease PerM	355
639001848	436	47.97	2	436	7	436	5.0e-128	451	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
639001849	157	47.77	1	157	1	157	2.0e-50	191	COG1225	Peroxiredoxin	157
639001850	177	43.18	1	176	1	176	7.0e-49	186	COG2716	Glycine cleavage system regulatory protein	176
639001851	291	51.54	1	291	4	296	3.0e-86	311	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
639001852	352	21.7	9	351	8	341	1.0e-16	81.2	COG3317	Uncharacterized lipoprotein	342
639001853	1299	36.12	163	991	3	743	0.0e+00	694	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
639001853	1299	40.7	1043	1299	2	231	6.0e-66	246	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
639001856	267	27.98	26	257	44	281	8.0e-29	120	COG1864	DNA/RNA endonuclease G, NUC1	281
639001859	564	27.44	4	216	3	197	2.0e-17	84.4	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
639001863	317	28.91	63	315	1	228	2.0e-19	89.8	COG3039	Transposase and inactivated derivatives, IS5 family	230
639001870	119	32.2	1	116	18	133	5.0e-06	43.4	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
639001872	185	32.39	30	165	1	142	3.0e-16	78.1	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
639001873	292	25.21	10	237	15	238	1.0e-25	110	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
639001875	145	31.97	19	139	12	128	2.0e-16	78.8	COG3439	Uncharacterized conserved protein, DUF302 family	137
639001876	631	31.26	1	592	23	526	7.0e-96	345	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
639001880	388	27.37	25	378	2	328	4.0e-36	145	COG3660	Mitochondrial fission protein ELM1	329
639001881	851	27.54	454	745	2	299	8.0e-28	119	COG3660	Mitochondrial fission protein ELM1	329
639001883	137	28.93	1	119	3	118	1.0e-10	58.6	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
639001886	406	28.43	8	402	2	374	3.0e-30	126	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639001891	357	29.4	1	347	27	400	6.0e-70	258	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
639001892	413	46.94	1	337	5	347	6.0e-94	337	COG1171	Threonine dehydratase	347
639001893	612	18.46	144	542	22	425	1.0e-16	81.5	COG5421	Transposase	480
639001896	167	26.09	19	133	20	129	8.0e-08	50	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
639001897	634	27.43	283	626	37	380	5.0e-36	146	COG0672	High-affinity Fe2+/Pb2+ permease	383
639001899	315	31.37	1	315	4	322	3.0e-58	219	COG0598	Mg2+ and Co2+ transporter CorA	322
639001903	734	21.06	6	732	12	768	1.0e-39	158	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
639001904	228	44.22	27	225	4	181	1.0e-40	160	COG3803	Uncharacterized conserved protein, DUF924 family	182
639001905	681	25.27	42	678	7	574	4.0e-66	246	COG0018	Arginyl-tRNA synthetase	577
639001907	161	26.76	10	151	13	144	4.0e-19	87.8	COG0071	Molecular chaperone IbpA, HSP20 family	146
639001908	137	33.33	19	135	27	146	7.0e-18	83.1	COG0071	Molecular chaperone IbpA, HSP20 family	146
639001914	498	29.32	22	492	38	438	3.0e-57	216	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
639001927	311	36.69	1	305	1	302	3.0e-57	215	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
639001929	565	40.56	2	553	5	558	7.0e-113	401	COG1966	Carbon starvation protein CstA	575
639001930	252	46.29	9	236	3	228	6.0e-69	254	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
639001931	422	48.28	12	417	1	389	0.0e+00	474	COG0448	ADP-glucose pyrophosphorylase	393
639001932	234	42.79	13	211	3	202	6.0e-31	127	COG3222	Uncharacterized conserved protein, glycosyltransferase A (GT-A) superfamily, DUF2064 family	211
639001935	137	30.58	16	130	16	132	3.0e-11	61.1	COG2346	Truncated hemoglobin YjbI	133
639001936	140	32.52	16	132	15	133	3.0e-09	54.5	COG2346	Truncated hemoglobin YjbI	133
639001937	333	41.77	1	315	1	311	1.0e-79	289	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
639001939	91	40.74	4	84	12	91	3.0e-08	50	COG5304	Predicted DNA binding protein, CopG/RHH family	92
639001943	149	33.61	5	121	1	122	2.0e-18	85.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
639001944	311	45.22	15	285	23	294	4.0e-69	255	COG1230	Co/Zn/Cd efflux system component	296
639001946	259	27.88	1	258	37	294	4.0e-17	82	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
639001947	246	34.63	1	222	4	231	6.0e-31	127	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
639001948	269	43.53	1	253	1	254	7.0e-69	254	COG3228	Mlc titration factor MtfA, regulates ptsG expression	266
639001949	356	39.33	31	351	1	324	3.0e-76	279	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
639001950	153	28.95	3	153	2	152	8.0e-18	83	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
639001951	455	56.04	4	455	2	456	0.0e+00	563	COG3572	Gamma-glutamylcysteine synthetase	456
639001952	514	39.1	344	499	3	151	2.0e-19	90.8	COG0645	Predicted kinase	170
639001952	514	42.94	11	341	5	337	1.0e-78	287	COG2187	Aminoglycoside phosphotransferase family enzyme	337
639001953	326	51.14	3	309	1	299	2.0e-105	376	COG0031	Cysteine synthase	300
639001954	247	48.81	3	245	2	250	7.0e-54	203	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
639001956	208	31.25	1	208	24	223	4.0e-17	81.7	COG0705	Membrane associated serine protease, rhomboid family	228
639001957	443	40.33	12	432	5	416	4.0e-82	298	COG4949	Uncharacterized membrane-anchored protein	424
639001959	654	28.85	342	640	25	276	4.0e-23	103	COG1234	Ribonuclease BN, tRNA processing enzyme	292
639001961	70	58.73	7	68	4	66	1.0e-20	91.7	COG1278	Cold shock protein, CspA family	67
639001962	333	28.8	23	331	17	326	2.0e-51	196	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
639001963	503	53.78	1	340	5	347	8.0e-121	427	COG1171	Threonine dehydratase	347
639001964	220	49.78	1	219	1	227	2.0e-72	265	COG0120	Ribose 5-phosphate isomerase	227
639001966	159	45.31	4	130	8	135	1.0e-36	145	COG0314	Molybdopterin synthase catalytic subunit	149
639001968	349	44.79	27	349	2	322	2.0e-89	322	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
639001969	104	39	3	102	4	102	2.0e-12	64.5	COG1993	PII-like signaling protein	109
639001970	124	43.55	1	124	2	125	2.0e-16	77.9	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
639001975	1004	23.19	42	1004	17	914	1.0e-107	385	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
639001976	710	18.45	271	672	1	391	4.0e-16	80.5	COG0732	Restriction endonuclease S subunit	391
639001976	710	35.03	10	164	12	162	2.0e-17	84.7	COG3236	Predicted NAD-dependent protein-ADP-ribosyltransferase YbiA, DUF1768 family	162
639001977	767	26.51	3	558	1	474	5.0e-54	206	COG0286	Type I restriction-modification system, DNA methylase subunit	489
639001981	279	40.58	70	272	1	200	7.0e-58	217	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
639001982	110	48.67	1	109	1	112	4.0e-22	96.5	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
639001983	364	46.97	27	364	1	339	2.0e-93	336	COG0309	Hydrogenase maturation factor	339
639001984	390	55.95	1	369	1	363	0.0e+00	495	COG0409	Hydrogenase maturation factor	364
639001985	92	50.6	1	83	1	77	2.0e-17	80.3	COG0298	Hydrogenase maturation factor	82
639001986	781	46.82	6	771	3	746	0.0e+00	810	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
639001987	142	40.35	20	130	41	154	3.0e-11	61.1	COG0680	Ni,Fe-hydrogenase maturation factor	160
639001988	429	31.94	4	427	3	431	4.0e-76	278	COG3259	Coenzyme F420-reducing hydrogenase, alpha subunit	441
639001989	260	28.25	6	219	2	220	1.0e-36	146	COG1941	Coenzyme F420-reducing hydrogenase, gamma subunit	247
639001990	279	29.5	10	268	5	248	4.0e-37	148	COG0543	NAD(P)H-flavin reductase	252
639001993	339	32.38	31	337	21	331	1.0e-47	183	COG2187	Aminoglycoside phosphotransferase family enzyme	337
639001998	310	42.01	16	301	3	276	7.0e-61	227	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
639002000	349	25	1	170	1	184	6.0e-10	58.9	COG1988	Membrane-bound metal-dependent hydrolase YbcI, DUF457 family	190
639002001	549	38	1	546	2	546	0.0e+00	508	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
639002002	479	36.52	4	469	1	458	2.0e-100	360	COG0415	Deoxyribodipyrimidine photolyase	461
639002003	361	34.88	21	354	13	398	5.0e-65	241	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
639002005	338	36.09	1	334	1	325	3.0e-58	219	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
639002007	237	22.94	55	224	42	190	1.0e-13	70.6	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
639002009	474	31.43	1	445	1	454	4.0e-76	279	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
639002010	362	42.19	38	355	7	312	2.0e-77	283	COG0462	Phosphoribosylpyrophosphate synthetase	314
639002011	1117	23.7	1	1095	1	1113	2.0e-89	324	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
639002013	544	34.43	5	457	1	396	1.0e-72	267	COG0644	Dehydrogenase (flavoprotein)	396
639002014	532	33.65	9	527	11	523	3.0e-97	349	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
639002017	275	40.44	1	272	2	273	3.0e-48	185	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
639002018	245	43.9	4	244	2	247	1.0e-71	263	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
639002019	313	27.67	28	312	9	301	1.0e-49	190	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
639002020	114	38.94	1	111	1	110	1.0e-26	112	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
639002021	194	38.95	2	191	34	213	2.0e-35	142	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
639002022	191	25.2	1	123	1	124	1.0e-11	63.2	COG3293	Transposase	124
639002026	431	38.67	1	417	16	446	3.0e-117	415	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
639002028	652	36.59	20	631	7	638	3.0e-121	429	COG1199	Rad3-related DNA helicase	654
639002030	772	39.54	110	752	14	647	0.0e+00	513	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
639002031	210	33.55	45	196	12	162	1.0e-17	83.1	COG1495	Disulfide bond formation protein DsbB	170
639002032	834	29.01	125	509	5	379	4.0e-48	186	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
639002033	499	29.05	89	491	1	434	3.0e-55	209	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
639002034	111	49.49	12	109	11	109	3.0e-26	109	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
639002035	147	43.26	2	141	1	141	1.0e-35	142	COG0822	NifU homolog involved in Fe-S cluster formation	150
639002036	419	51.86	18	417	5	405	0.0e+00	465	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
639002037	443	28.85	16	421	3	399	2.0e-71	263	COG0719	Fe-S cluster assembly scaffold protein SufB	412
639002038	251	63.49	1	251	1	248	6.0e-98	350	COG0396	Fe-S cluster assembly ATPase SufC	251
639002039	482	41.74	37	480	1	412	2.0e-120	426	COG0719	Fe-S cluster assembly scaffold protein SufB	412
639002040	153	31.54	3	131	2	130	6.0e-24	103	COG1959	DNA-binding transcriptional regulator, IscR family	150
639002041	390	36.99	13	388	1	392	3.0e-75	275	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
639002042	505	36.56	17	505	20	518	1.0e-79	291	COG0815	Apolipoprotein N-acyltransferase	518
639002043	294	49.83	1	288	1	286	1.0e-89	323	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
639002044	154	45.7	1	149	2	152	5.0e-37	146	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
639002045	339	52.96	10	326	16	335	2.0e-108	386	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
639002046	443	49.65	1	427	14	436	0.0e+00	516	COG0621	tRNA A37 methylthiotransferase MiaB	437
639002047	484	49.1	15	346	2	332	4.0e-123	435	COG0836	Mannose-1-phosphate guanylyltransferase	333
639002047	484	50	357	482	2	127	2.0e-35	144	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
639002048	447	53.77	1	424	1	413	0.0e+00	549	COG1004	UDP-glucose 6-dehydrogenase	414
639002050	457	36.91	1	454	3	463	8.0e-105	374	COG1109	Phosphomannomutase	464
639002051	621	44.37	21	595	1	549	0.0e+00	546	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
639002052	405	54.98	188	397	2	212	9.0e-59	221	COG0560	Phosphoserine phosphatase	212
639002053	374	60.92	1	371	1	371	0.0e+00	507	COG0686	Alanine dehydrogenase	371
639002055	135	64.29	3	114	4	114	2.0e-37	147	COG0335	Ribosomal protein L19	115
639002056	262	54.77	7	246	1	239	4.0e-94	337	COG0336	tRNA G37 N-methylase TrmD	240
639002057	173	42.01	10	173	6	172	3.0e-41	161	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
639002058	89	60.92	1	87	1	86	2.0e-26	111	COG0228	Ribosomal protein S16	87
639002059	458	56.95	1	453	1	451	0.0e+00	603	COG0541	Signal recognition particle GTPase	451
639002060	268	37.22	3	268	1	265	1.0e-48	186	COG4137	ABC-type uncharacterized transport system, permease component	265
639002061	414	52.58	1	404	11	417	0.0e+00	475	COG4536	Mg2+ and Co2+ transporter CorB, contains DUF21, CBS pair, and CorC-HlyC domains	423
639002062	469	57.36	1	465	1	463	0.0e+00	657	COG0215	Cysteinyl-tRNA synthetase	464
639002063	452	35.22	1	445	22	469	3.0e-88	319	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
639002064	259	42.5	12	247	1	236	2.0e-52	198	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
639002065	149	45.89	1	145	1	146	3.0e-41	161	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
639002066	473	39.16	21	469	7	437	2.0e-83	303	COG0733	Na+-dependent transporter, SNF family	439
639002067	163	57.52	11	163	1	152	9.0e-54	202	COG0691	tmRNA-binding protein	153
639002068	269	33.47	30	266	20	255	2.0e-41	162	COG1877	Trehalose-6-phosphatase	266
639002069	454	42.63	1	440	62	485	2.0e-118	419	COG0380	Trehalose-6-phosphate synthase	486
639002076	1067	33.21	5	1038	3	962	0.0e+00	705	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
639002077	1090	21.33	311	1014	31	673	8.0e-44	172	COG1204	Replicative superfamily II helicase	766
639002079	421	18.51	82	407	81	391	2.0e-16	80.5	COG0732	Restriction endonuclease S subunit	391
639002080	522	38.42	26	520	7	488	2.0e-112	399	COG0286	Type I restriction-modification system, DNA methylase subunit	489
639002087	141	41.91	1	133	1	135	5.0e-25	106	COG1569	Predicted nucleic acid-binding protein, contains PIN domain	142
639002091	328	28.91	74	326	1	228	2.0e-19	90.6	COG3039	Transposase and inactivated derivatives, IS5 family	230
639002107	100	41.3	1	90	2	92	7.0e-11	58.9	COG3668	Plasmid stabilization system protein ParE	98
639002110	319	18.1	6	231	1	212	7.0e-11	61.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
639002115	483	44.11	3	461	10	469	0.0e+00	465	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
639002117	159	21.29	6	159	3	146	8.0e-08	50	COG3418	Flagellar biosynthesis/type III secretory pathway chaperone	146
639002119	244	29.74	50	244	30	220	8.0e-28	117	COG1261	Flagella basal body P-ring formation protein FlgA	220
639002120	131	42.54	2	131	1	133	2.0e-28	117	COG1815	Flagellar basal body rod protein FlgB	133
639002121	139	45.26	3	139	1	137	2.0e-33	135	COG1558	Flagellar basal body rod protein FlgC	137
639002122	221	31.08	2	221	3	222	7.0e-32	130	COG1843	Flagellar hook assembly protein FlgD	222
639002123	400	38.48	1	400	3	422	1.0e-75	277	COG1749	Flagellar hook protein FlgE	423
639002124	246	45.63	1	246	1	251	7.0e-69	253	COG4787	Flagellar basal body rod protein FlgF	251
639002125	261	54.34	1	261	1	264	7.0e-81	293	COG4786	Flagellar basal body rod protein FlgG	265
639002127	370	31.4	163	368	76	282	1.0e-18	88	COG0842	ABC-type multidrug transport system, permease component	286
639002128	381	27.67	174	379	77	282	4.0e-17	82.7	COG0842	ABC-type multidrug transport system, permease component	286
639002129	584	51.98	337	560	4	230	2.0e-71	264	COG1131	ABC-type multidrug transport system, ATPase component	293
639002131	441	38.16	19	396	5	368	2.0e-86	312	COG0301	Adenylyl- and sulfurtransferase ThiI, participates in tRNA 4-thiouridine and thiamine biosynthesis	383
639002132	127	52.89	4	124	3	120	9.0e-20	89.1	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
639002133	441	22.19	90	435	7	328	1.0e-24	107	COG0642	Signal transduction histidine kinase	336
639002135	418	32.52	33	394	19	387	2.0e-76	279	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
639002136	614	34.9	281	578	25	315	7.0e-54	205	COG0616	Periplasmic serine protease, ClpP class	317
639002138	407	55.91	1	405	1	401	0.0e+00	523	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
639002139	447	63.51	1	444	1	441	0.0e+00	595	COG3724	Succinylarginine dihydrolase	442
639002140	511	37.17	27	483	2	455	1.0e-101	363	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
639002141	226	20.5	13	200	5	201	2.0e-18	86.1	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
639002142	572	49.3	71	570	6	498	0.0e+00	559	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
639002143	409	44.11	11	409	4	396	1.0e-107	383	COG1459	Type II secretory pathway, component PulF	397
639002144	305	45.71	24	302	5	254	7.0e-39	154	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
639002145	200	42.86	1	196	2	197	4.0e-46	177	COG0237	Dephospho-CoA kinase	201
639002146	279	34.4	28	277	2	244	2.0e-43	169	COG4582	Cell division protein ZapD, interacts with FtsZ	244
639002147	65	49.15	1	59	6	64	1.0e-14	71.2	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
639002148	316	34.04	131	315	5	192	5.0e-33	135	COG0352	Thiamine monophosphate synthase	211
639002149	405	46.93	1	405	2	404	2.0e-115	409	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
639002150	904	58.15	2	897	1	822	0.0e+00	1089	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
639002152	303	61.59	1	301	1	300	1.0e-122	433	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
639002153	380	54.87	1	339	1	338	6.0e-96	344	COG0206	Cell division GTPase FtsZ	338
639002154	412	50.96	3	411	1	417	0.0e+00	470	COG0849	Cell division ATPase FtsA	418
639002155	264	29.58	26	257	27	263	4.0e-30	125	COG1589	Cell division septal protein FtsQ	269
639002156	315	43.41	15	305	3	313	2.0e-76	279	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
639002157	299	44.48	8	295	3	291	9.0e-77	280	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
639002158	482	51.73	17	475	4	457	0.0e+00	532	COG0773	UDP-N-acetylmuramate-alanine ligase	459
639002159	360	43.58	5	360	2	356	2.0e-87	316	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
639002160	401	43.87	26	388	14	375	3.0e-82	299	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
639002161	445	42.95	8	441	11	445	4.0e-118	418	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
639002162	360	43.52	20	360	1	316	6.0e-54	205	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
639002163	453	43.18	4	441	3	448	3.0e-108	385	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
639002164	502	40.97	28	500	10	474	1.0e-116	413	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
639002165	575	39.46	7	559	6	597	6.0e-126	444	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
639002167	303	48.69	2	303	11	313	6.0e-97	347	COG0275	16S rRNA C1402 N4-methylase RsmH	314
639002168	135	49.63	1	135	16	146	8.0e-36	142	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
639002169	288	50.89	7	287	1	275	1.0e-87	316	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
639002170	660	31.6	26	642	12	603	1.0e-71	264	COG3107	Outer membrane lipoprotein LpoA, binds and activates PBP1a	604
639002171	119	49.11	8	117	2	113	8.0e-31	125	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
639002172	180	54.38	2	161	19	175	4.0e-53	200	COG0279	Phosphoheptose isomerase	176
639002173	132	47.68	1	132	5	155	2.0e-40	158	COG2969	Stringent starvation protein B	155
639002174	182	32.82	1	182	19	210	1.0e-20	93	COG0625	Glutathione S-transferase	211
639002175	255	33.33	4	255	10	250	5.0e-39	154	COG2857	Cytochrome c1	250
639002176	439	50.39	6	393	3	374	1.0e-93	336	COG1290	Cytochrome b subunit of the bc complex	381
639002177	201	33.33	3	197	2	171	1.0e-28	119	COG0723	Rieske Fe-S protein	177
639002178	252	40.16	2	252	1	250	4.0e-59	221	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
639002179	389	48.62	45	367	17	324	8.0e-65	241	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
639002180	421	51.75	13	412	27	423	0.0e+00	502	COG0141	Histidinol dehydrogenase	425
639002182	419	61.43	1	419	1	420	0.0e+00	609	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
639002183	79	42.31	2	79	1	78	1.0e-16	78	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
639002184	119	38.64	11	98	10	97	2.0e-14	71.4	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
639002185	197	35.6	1	190	15	202	5.0e-42	164	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
639002187	258	49.42	1	257	8	263	1.0e-62	233	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
639002188	281	59.38	13	267	8	263	3.0e-97	348	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
639002189	337	59	22	220	3	202	1.0e-65	244	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
639002190	185	48.21	16	183	1	168	2.0e-50	192	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
639002191	189	24	11	184	9	182	4.0e-19	88.1	COG3117	Lipopolysaccharide export system protein LptC	188
639002192	189	28.74	12	177	1	162	2.0e-20	92.7	COG1934	Lipopolysaccharide export system protein LptA	173
639002193	249	65.69	12	249	5	243	8.0e-105	373	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
639002194	493	45.03	1	492	1	443	4.0e-127	448	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
639002195	108	49.09	1	108	1	110	4.0e-24	103	COG1544	Ribosome-associated translation inhibitor RaiA	110
639002196	156	38.67	5	152	4	152	2.0e-30	125	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
639002198	288	49.13	1	286	1	286	1.0e-93	336	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
639002199	95	50	8	93	2	87	1.0e-21	94.5	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
639002201	453	37.03	26	453	7	454	6.0e-84	304	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
639002202	486	42.67	25	483	2	454	7.0e-118	417	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
639002203	287	38.52	7	271	4	263	3.0e-49	189	COG0388	Predicted amidohydrolase	274
639002204	1252	24.76	1	1235	8	1259	1.0e-125	445	COG3164	Uncharacterized conserved protein YhdP, contains DUF3971 and AsmA2 domains	1271
639002205	488	46.63	2	488	1	483	0.0e+00	466	COG1530	Ribonuclease G or E	487
639002206	203	53.76	7	191	3	186	2.0e-59	221	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
639002207	156	41.29	1	154	1	155	8.0e-49	186	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
639002208	124	48.57	6	110	1	105	2.0e-29	121	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
639002209	222	38.46	12	217	5	195	2.0e-41	162	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
639002210	421	55.88	6	421	1	417	0.0e+00	575	COG0014	Gamma-glutamyl phosphate reductase	417
639002211	340	32.83	4	330	1	327	1.0e-48	187	COG1466	DNA polymerase III, delta subunit	334
639002212	168	27.44	6	168	4	163	4.0e-14	71.1	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
639002213	867	50.75	6	866	1	814	0.0e+00	1044	COG0495	Leucyl-tRNA synthetase	814
639002215	245	43.93	22	234	1	209	2.0e-48	185	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
639002216	234	36.02	49	234	1	180	1.0e-31	130	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
639002218	258	22.45	7	250	5	229	2.0e-18	86.2	COG2859	Uncharacterized protein	237
639002221	69	31.34	3	69	10	76	2.0e-12	64.2	COG2442	Uncharacterized conserved protein, DUF433 family	79
639002223	141	34.67	1	75	1	73	1.0e-09	55.8	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
639002229	583	56.31	1	561	1	563	0.0e+00	678	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
639002230	195	25.65	14	195	9	198	6.0e-12	64.1	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
639002232	211	38.27	1	190	1	193	6.0e-58	217	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
639002234	329	30.43	34	300	1	275	9.0e-46	177	COG0616	Periplasmic serine protease, ClpP class	317
639002235	80	35.53	2	76	1	76	5.0e-15	73	COG0425	TusA-related sulfurtransferase	78
639002237	334	59.07	43	323	24	302	3.0e-122	431	COG0320	Lipoate synthase	306
639002238	310	45.94	21	303	18	300	5.0e-81	294	COG0109	Polyprenyltransferase (heme O synthase)	304
639002239	345	32.52	19	345	26	319	2.0e-35	143	COG1612	Heme A synthase	323
639002241	243	24.79	8	239	11	242	3.0e-28	118	COG3346	Cytochrome oxidase assembly protein ShyY1	252
639002243	287	35.09	59	286	10	206	4.0e-38	151	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
639002245	536	53.11	15	523	2	515	0.0e+00	530	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
639002246	293	31.62	17	285	3	240	8.0e-51	194	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
639002247	186	27.4	16	157	19	160	2.0e-13	68.8	COG5488	Uncharacterized membrane protein	164
639002249	340	55.59	8	327	9	328	4.0e-112	398	COG0502	Biotin synthase or related enzyme	335
639002250	219	42.59	2	215	13	224	1.0e-42	166	COG1040	Predicted amidophosphoribosyltransferases	225
639002251	292	42.01	4	290	2	289	1.0e-46	180	COG0382	4-hydroxybenzoate polyprenyltransferase	289
639002252	171	37.58	4	165	17	172	3.0e-22	98.1	COG3161	4-hydroxybenzoate synthetase (chorismate-pyruvate lyase)	174
639002253	697	54.98	20	690	20	677	0.0e+00	808	COG1200	RecG-like helicase	677
639002254	128	50.39	1	126	2	128	1.0e-34	138	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
639002255	726	42.39	23	723	11	700	0.0e+00	797	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
639002256	85	60.87	1	67	1	69	7.0e-13	65.3	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
639002257	179	51.88	3	162	32	191	2.0e-59	221	COG0194	Guanylate kinase	191
639002258	288	48.62	1	288	1	290	2.0e-74	272	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
639002259	238	56.96	1	236	8	229	7.0e-72	263	COG0689	Ribonuclease PH	230
639002260	198	48.72	1	194	1	190	4.0e-62	230	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
639002261	369	39.52	2	366	46	410	6.0e-98	351	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
639002262	96	36.36	1	96	28	126	3.0e-11	60.3	COG3094	Uncharacterized membrane protein SirB2	129
639002263	85	46.51	1	85	1	74	2.0e-19	86.8	COG0254	Ribosomal protein L31	75
639002264	433	51.6	28	431	1	390	0.0e+00	463	COG0372	Citrate synthase	390
639002266	819	48.83	9	816	1	785	0.0e+00	882	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
639002267	369	46.99	20	367	5	352	2.0e-92	333	COG4972	Tfp pilus assembly protein, ATPase PilM	354
639002268	191	35.94	1	191	3	194	5.0e-32	130	COG3166	Tfp pilus assembly protein PilN	206
639002269	205	42.08	4	205	6	200	3.0e-49	188	COG3167	Tfp pilus assembly protein PilO	211
639002270	183	38.24	15	183	2	168	9.0e-34	136	COG3168	Tfp pilus assembly protein PilP	170
639002271	686	32	14	680	21	709	4.0e-107	382	COG4796	Type II secretory pathway, component HofQ	709
639002272	174	50	6	168	4	166	1.0e-46	178	COG0703	Shikimate kinase	172
639002273	371	58.06	12	368	3	360	0.0e+00	464	COG0337	3-dehydroquinate synthetase	360
639002275	274	26.77	6	128	2	123	2.0e-08	53.2	COG3293	Transposase	124
639002276	317	39.62	1	313	4	321	1.0e-84	306	COG1171	Threonine dehydratase	347
639002280	90	39.44	17	87	3	68	6.0e-07	45.7	COG3831	WGR domain, predicted DNA-binding domain in MolR	85
639002285	84	35	5	84	2	80	3.0e-08	50.1	COG4118	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor	84
639002286	140	24.46	1	135	1	137	1.0e-06	45.9	COG1848	Predicted nucleic acid-binding protein, contains PIN domain	140
639002287	218	49.53	1	211	53	261	1.0e-54	206	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
639002288	530	36.47	15	519	13	526	2.0e-95	343	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
639002289	266	43.51	6	265	2	256	3.0e-66	245	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
639002290	295	37.41	1	263	43	301	6.0e-61	227	COG0042	tRNA-dihydrouridine synthase	323
639002295	332	26.33	6	331	26	358	2.0e-54	206	COG5345	Uncharacterized protein	358
639002296	279	49.8	1	247	7	245	4.0e-66	244	COG0121	Predicted glutamine amidotransferase	252
639002300	210	43.46	10	199	5	192	6.0e-41	160	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
639002301	418	49.5	21	417	7	404	2.0e-119	422	COG0303	Molybdopterin biosynthesis enzyme	404
639002302	416	37.14	38	413	1	369	4.0e-37	149	COG3174	Uncharacterized membrane protein, DUF4010 family	371
639002304	411	42.61	15	403	65	462	1.0e-101	363	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
639002316	84	42.17	2	84	28	110	5.0e-14	69.6	COG4634	Predicted nuclease, contains PIN domain, potential toxin-antitoxin system component	113
639002317	75	56.52	1	69	6	74	2.0e-21	93.9	COG2442	Uncharacterized conserved protein, DUF433 family	79
639002319	224	21.6	2	124	18	136	2.0e-11	63	COG1943	REP element-mobilizing transposase RayT	136
639002320	145	30.43	1	136	1	135	7.0e-17	79.8	COG1848	Predicted nucleic acid-binding protein, contains PIN domain	140
639002330	132	30.51	14	130	1	114	1.0e-14	71.9	COG3628	Phage baseplate assembly protein W	116
639002342	369	69.38	1	369	1	366	0.0e+00	564	COG1062	Zn-dependent alcohol dehydrogenase	366
639002343	292	37.86	5	282	6	313	1.0e-67	249	COG0627	S-formylglutathione hydrolase FrmB	316
639002345	73	38.81	1	67	1	66	2.0e-08	51.1	COG1724	Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family	66
639002346	128	33.33	1	124	1	125	6.0e-16	76.6	COG5611	Predicted nucleic-acid-binding protein, contains PIN domain	130
639002349	252	22.96	2	252	44	268	1.0e-13	70.5	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
639002350	212	39.51	2	205	32	235	3.0e-48	185	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
639002352	376	27.95	4	342	9	346	2.0e-43	170	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
639002357	407	32.02	4	401	2	407	8.0e-78	284	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
639002359	400	32.21	1	372	16	398	9.0e-48	184	COG2223	Nitrate/nitrite transporter NarK	417
639002366	127	36.15	2	127	24	153	3.0e-14	70.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
639002381	400	38.96	148	394	1	232	3.0e-52	199	COG1018	Ferredoxin-NADP reductase	266
639002381	400	50	1	148	1	150	3.0e-49	189	COG1017	Hemoglobin-like flavoprotein	150
639002382	240	23.94	1	140	1	136	2.0e-14	72.6	COG1943	REP element-mobilizing transposase RayT	136
639002383	244	25.97	7	238	3	255	7.0e-10	57.6	COG0428	Zinc transporter ZupT	266
639002390	317	28.91	63	315	1	228	2.0e-19	90.2	COG3039	Transposase and inactivated derivatives, IS5 family	230
639002393	370	35.1	34	370	10	342	6.0e-93	334	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
639002394	955	40.26	191	931	1	694	0.0e+00	654	COG0209	Ribonucleotide reductase alpha subunit	696
639002395	308	31.67	3	301	1	296	5.0e-30	125	COG0583	DNA-binding transcriptional regulator, LysR family	297
639002396	773	59.52	439	769	1	329	3.0e-120	426	COG0620	Methionine synthase II (cobalamin-independent)	330
639002398	227	23.41	16	220	6	202	4.0e-16	78.4	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
639002399	389	41.72	40	377	29	354	2.0e-78	286	COG5621	Predicted secreted hydrolase	354
639002400	837	18.66	474	837	2	419	3.0e-14	74.4	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
639002400	837	23.88	6	386	14	405	4.0e-24	107	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
639002401	241	48.44	21	240	1	224	1.0e-68	252	COG1136	ABC-type lipoprotein export system, ATPase component	226
639002403	390	27.43	54	371	63	402	1.0e-25	111	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
639002405	298	39.62	138	296	1	159	3.0e-38	152	COG3272	Uncharacterized conserved protein YbgA, DUF1722 family	163
639002406	331	31.05	16	314	1	303	9.0e-44	170	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
639002407	52	66.04	1	52	4	56	2.0e-08	51.3	COG0401	Uncharacterized membrane protein YqaE, homolog of Blt101, UPF0057 family	56
639002409	357	25.23	2	323	3	306	4.0e-33	135	COG3021	Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily	309
639002410	336	30.14	1	335	1	314	6.0e-52	198	COG0451	Nucleoside-diphosphate-sugar epimerase	314
639002411	425	39.29	6	422	9	429	2.0e-121	429	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
639002413	221	34.02	19	210	9	202	5.0e-40	157	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
639002416	517	50.2	14	515	22	530	0.0e+00	586	COG3131	Periplasmic glucans biosynthesis protein	534
639002417	661	45.15	12	626	44	652	0.0e+00	597	COG2943	Membrane glycosyltransferase	736
639002418	118	25.78	1	118	1	126	3.0e-10	57.2	COG1553	Sulfur relay (sulfurtransferase) complex TusBCD TusD component, DsrE family	126
639002426	315	25.57	8	295	5	346	4.0e-39	155	COG1566	Multidrug resistance efflux pump	352
639002431	551	22.92	16	248	7	245	6.0e-16	79.6	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
639002433	113	44.19	17	100	7	92	5.0e-18	83	COG2257	Type III secretion system substrate exporter, FlhB-like	92
639002441	429	44.37	1	427	29	462	1.0e-114	406	COG0513	Superfamily II DNA and RNA helicase	513
639002445	466	39.22	8	450	7	463	0.0e+00	496	COG1156	Archaeal/vacuolar-type H+-ATPase subunit B/Vma2	463
639002446	201	26.57	1	199	2	208	3.0e-17	81.9	COG1394	Archaeal/vacuolar-type H+-ATPase subunit D/Vma8	211
639002447	593	22.37	1	583	1	649	3.0e-53	203	COG1269	Archaeal/vacuolar-type H+-ATPase subunit I/STV1	660
639002451	619	45.1	51	557	33	533	0.0e+00	629	COG1155	Archaeal/vacuolar-type H+-ATPase catalytic subunit A/Vma1	588
639002453	335	39.82	6	335	2	337	4.0e-83	301	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
639002455	309	46.1	1	308	1	305	3.0e-80	291	COG3781	Predicted membrane chloride channel, bestrophin family	306
639002464	502	21.97	60	486	60	532	9.0e-16	78.8	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
639002468	408	26.71	1	393	1	380	1.0e-47	184	COG3497	Phage tail sheath protein FI	394
639002475	315	23.91	31	303	20	313	9.0e-18	84.7	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
639002476	172	26.16	1	172	30	182	5.0e-20	90.8	COG3271	Predicted double-glycine peptidase	201
639002478	224	32.62	21	207	28	206	2.0e-27	116	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
639002487	615	52.85	4	597	6	589	0.0e+00	705	COG0514	Superfamily II DNA helicase RecQ	590
639002489	300	38.67	119	299	13	180	4.0e-37	148	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
639002490	327	24.59	26	309	4	281	1.0e-12	67.9	COG4974	Site-specific recombinase XerD	300
639002492	806	26.01	357	806	42	587	1.0e-52	202	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
639002492	806	27.71	1	361	5	393	2.0e-33	138	COG3182	Uncharacterized iron-regulated membrane protein	442
639002493	732	35.84	50	732	31	719	0.0e+00	524	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
639002494	561	40.04	4	553	3	546	3.0e-122	432	COG4615	ABC-type siderophore export system, fused ATPase and permease components	546
639002496	1563	41.34	280	941	1	641	0.0e+00	470	COG1020	Non-ribosomal peptide synthetase component F	642
639002497	1039	33.99	205	847	2	642	4.0e-115	409	COG1020	Non-ribosomal peptide synthetase component F	642
639002498	348	19.08	54	333	30	271	2.0e-10	60.4	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
639002499	2660	43.63	1331	1986	1	642	0.0e+00	490	COG1020	Non-ribosomal peptide synthetase component F	642
639002501	1076	34.39	234	873	1	642	1.0e-85	312	COG1020	Non-ribosomal peptide synthetase component F	642
639002502	3074	19.59	2767	3044	28	271	1.0e-05	48	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
639002502	3074	38.98	1431	2083	1	642	4.0e-125	444	COG1020	Non-ribosomal peptide synthetase component F	642
639002503	71	52.24	2	68	5	71	3.0e-20	90.1	COG3251	Uncharacterized conserved protein YbdZ, MbtH family	71
639002504	832	20.92	1	820	2	760	3.0e-54	207	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
639002505	335	17.31	10	316	1	266	4.0e-07	49.2	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
639002509	261	36.92	6	259	4	251	6.0e-43	167	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
639002513	87	40.48	5	86	3	84	2.0e-15	73.8	COG4115	Toxin component of the Txe-Axe toxin-antitoxin module, Txe/YoeB family	84
639002514	80	36.14	1	80	3	85	7.0e-11	58.9	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
639002518	173	17.86	1	140	1	136	4.0e-07	47.9	COG1943	REP element-mobilizing transposase RayT	136
639002519	317	29.02	63	314	1	227	3.0e-19	89.4	COG3039	Transposase and inactivated derivatives, IS5 family	230
639002523	969	29.44	24	951	185	1100	0.0e+00	733	COG4913	Uncharacterized protein YPO0396	1104
639002525	104	31	4	99	1	100	2.0e-09	54.1	COG1695	DNA-binding transcriptional regulator, PadR family	138
639002526	409	34.64	14	191	4	182	4.0e-30	126	COG2059	Chromate transport protein ChrA	195
639002528	783	41.84	4	775	8	860	0.0e+00	674	COG4096	Type I site-specific restriction endonuclease, part of a restriction-modification system	875
639002529	483	32.16	1	481	5	487	3.0e-80	293	COG0286	Type I restriction-modification system, DNA methylase subunit	489
639002533	196	39.15	4	191	2	187	1.0e-40	159	COG4185	Predicted ABC-type ATPase	187
639002534	189	23.98	1	187	1	194	7.0e-08	50.7	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
639002541	140	27.69	1	65	2	66	2.0e-06	45	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
639002552	444	39.66	29	434	17	409	1.0e-97	350	COG2995	Uncharacterized paraquat-inducible protein A	418
639002553	547	39.23	1	544	4	550	0.0e+00	500	COG3008	Paraquat-inducible protein B	553
639002554	208	34.81	14	194	6	183	4.0e-28	118	COG3009	Uncharacterized lipoprotein YmbA	190
639002555	424	65.96	1	423	6	426	0.0e+00	643	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
639002557	274	44.03	1	265	1	267	1.0e-73	269	COG2162	Arylamine N-acetyltransferase	275
639002558	203	36.27	8	193	11	199	4.0e-29	121	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
639002559	206	34.76	1	206	3	206	4.0e-27	114	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
639002561	504	29.29	20	256	23	260	7.0e-35	142	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
639002563	128	28.35	5	128	4	129	8.0e-10	56.1	COG3744	PIN domain nuclease, a component of toxin-antitoxin system (PIN domain)	130
639002565	294	34.98	6	286	5	286	3.0e-68	252	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
639002566	256	30.95	20	227	1	209	4.0e-38	151	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
639002567	179	33.85	1	65	2	66	3.0e-09	55.2	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
639002569	688	50.36	6	687	2	682	0.0e+00	784	COG1770	Protease II	682
639002572	211	42.59	41	202	3	160	1.0e-39	156	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
639002573	226	32.64	8	194	1	172	2.0e-28	119	COG1335	Nicotinamidase-related amidase	205
639002575	526	63.38	1	526	2	528	0.0e+00	840	COG4108	Peptide chain release factor RF-3	528
639002576	158	58.87	8	148	10	148	1.0e-49	188	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
639002577	173	34.39	12	166	1	145	2.0e-31	128	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
639002578	405	48.79	1	403	2	411	2.0e-118	419	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
639002583	200	48.55	17	188	1	173	3.0e-61	228	COG0225	Peptide methionine sulfoxide reductase MsrA	174
639002585	216	45.92	16	210	11	194	4.0e-40	157	COG3145	Alkylated DNA repair dioxygenase AlkB	194
639002586	1045	47.34	1	1035	1	1027	0.0e+00	1083	COG3696	Cu/Ag efflux pump CusA	1027
639002587	401	30.77	70	390	48	363	2.0e-19	90.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
639002588	437	26.11	15	423	19	446	6.0e-21	95.6	COG1538	Outer membrane protein TolC	457
639002591	466	46.25	5	389	16	402	1.0e-105	377	COG3562	Capsule polysaccharide modification protein KpsS	403
639002592	736	46.7	22	702	6	665	0.0e+00	630	COG3563	Capsule polysaccharide export protein KpsC/LpsZ	671
639002593	370	33.42	1	368	1	357	7.0e-39	154	COG0675	Transposase	364
639002594	427	21.05	99	397	53	341	8.0e-18	85.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639002601	370	34.71	1	357	1	346	4.0e-41	162	COG0675	Transposase	364
639002602	119	46.3	14	67	8	61	7.0e-12	62.7	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
639002603	154	27.27	5	135	19	142	1.0e-06	45.8	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
639002604	368	28.61	9	321	3	314	3.0e-40	159	COG0451	Nucleoside-diphosphate-sugar epimerase	314
639002605	373	70.59	1	357	1	345	0.0e+00	566	COG1089	GDP-D-mannose dehydratase	345
639002608	256	30.4	4	238	8	250	2.0e-31	129	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
639002609	309	38.66	1	309	4	308	1.0e-63	236	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
639002610	221	29.3	1	207	10	218	2.0e-33	135	COG1083	CMP-N-acetylneuraminic acid synthetase	228
639002611	316	15.72	1	295	3	282	2.0e-13	69.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
639002612	257	25.76	4	228	7	217	1.0e-23	103	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
639002619	361	29.33	23	360	32	371	6.0e-53	201	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
639002620	221	36.65	1	219	24	243	2.0e-61	228	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
639002621	259	23.79	9	256	17	259	7.0e-21	94.5	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
639002622	575	23.53	86	283	25	225	2.0e-18	87.9	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
639002624	324	54.55	19	215	4	201	2.0e-62	232	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
639002625	256	28.7	12	228	1	215	2.0e-33	136	COG2102	Diphthamide synthase (EF-2-diphthine--ammonia ligase)	223
639002626	307	23.31	2	292	54	318	1.0e-23	104	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
639002630	159	55.1	10	107	1	98	1.0e-32	132	COG3526	Predicted selenoprotein, Rdx family	99
639002633	278	45.32	1	267	1	265	6.0e-79	287	COG0159	Tryptophan synthase alpha chain	265
639002634	303	60.88	7	300	1	293	2.0e-121	428	COG0777	Acetyl-CoA carboxylase beta subunit	294
639002635	426	40.24	1	419	2	421	1.0e-97	350	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
639002636	210	28.32	1	208	1	223	9.0e-16	77	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
639002637	188	35.21	1	141	1	142	4.0e-24	104	COG1286	Uncharacterized membrane protein, required for colicin V production	182
639002638	503	51.54	1	482	4	469	0.0e+00	598	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
639002639	399	47.1	4	397	1	396	2.0e-128	452	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
639002640	408	37.83	1	405	4	420	3.0e-71	262	COG2379	Glycerate-2-kinase	422
639002642	119	58.26	2	115	3	117	7.0e-38	149	COG3189	Uncharacterized conserved protein YeaO, DUF488 family	117
639002644	107	53.12	5	100	1	96	8.0e-23	98.8	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
639002645	144	34.43	9	126	1	120	2.0e-20	91.6	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
639002646	138	45.19	4	138	10	143	2.0e-36	144	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
639002647	553	42.37	1	553	1	556	0.0e+00	524	COG0497	DNA repair ATPase RecN	557
639002648	281	43.37	1	277	6	281	9.0e-67	247	COG0061	NAD kinase	281
639002649	331	41.09	2	331	16	344	4.0e-76	278	COG1420	Transcriptional regulator of heat shock response	346
639002650	206	38.34	1	193	1	193	2.0e-34	139	COG0576	Molecular chaperone GrpE (heat shock protein)	193
639002651	642	62.38	1	605	4	579	0.0e+00	667	COG0443	Molecular chaperone DnaK (HSP70)	579
639002652	378	58.47	1	375	1	371	0.0e+00	478	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
639002653	268	56.39	1	266	2	266	3.0e-90	325	COG0289	Dihydrodipicolinate reductase	266
639002656	339	37.3	24	336	2	302	4.0e-58	218	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
639002657	126	37.1	6	125	3	126	7.0e-13	66.1	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
639002658	126	36.75	7	123	1	117	5.0e-17	80.2	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
639002659	596	53.09	6	580	1	562	0.0e+00	623	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
639002660	259	56.6	26	259	1	231	2.0e-83	302	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
639002661	79	42.67	2	75	13	87	9.0e-13	65.3	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
639002663	547	55.79	9	535	9	512	0.0e+00	635	COG0029	Aspartate oxidase	518
639002664	200	36.07	7	189	1	177	4.0e-31	128	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
639002665	213	25.34	2	210	3	211	5.0e-09	54.6	COG3073	Negative regulator of sigma E activity	213
639002666	347	29.31	21	345	6	320	3.0e-45	175	COG3026	Negative regulator of sigma E activity	320
639002667	604	67.33	1	602	1	603	0.0e+00	1022	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
639002668	258	32.28	49	157	8	165	2.0e-14	73.5	COG0681	Signal peptidase I	166
639002670	226	48.48	1	226	4	233	1.0e-60	226	COG0571	dsRNA-specific ribonuclease	235
639002671	310	49.83	18	310	5	298	6.0e-104	370	COG1159	GTPase Era, involved in 16S rRNA processing	298
639002672	249	34.43	4	237	1	244	5.0e-43	167	COG1381	Recombinational DNA repair protein (RecF pathway)	251
639002673	254	61	11	248	2	242	1.0e-82	299	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
639002674	127	47.24	2	126	1	127	2.0e-31	127	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
639002675	239	41.82	2	109	9	115	1.0e-15	77.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
639002676	686	32.38	169	516	3	334	1.0e-39	158	COG0642	Signal transduction histidine kinase	336
639002677	260	29.76	5	202	6	163	4.0e-18	85.5	COG3298	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	164
639002678	450	36.38	11	437	2	432	2.0e-94	339	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
639002683	688	60.84	26	687	6	663	0.0e+00	1022	COG0021	Transketolase	663
639002684	348	45.15	1	329	1	286	6.0e-95	340	COG0191	Fructose/tagatose bisphosphate aldolase	286
639002685	294	63.19	1	288	1	286	6.0e-122	430	COG3954	Phosphoribulokinase	289
639002686	342	52.28	5	333	1	322	3.0e-118	418	COG0158	Fructose-1,6-bisphosphatase	326
639002687	323	26.64	14	311	2	277	5.0e-16	79	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
639002688	611	18.46	144	541	22	425	5.0e-13	70	COG5421	Transposase	480
639002689	439	31.75	35	382	24	371	5.0e-44	172	COG5659	SRSO17 transposase	385
639002690	113	30.77	1	87	1	91	6.0e-09	52.8	COG3293	Transposase	124
639002694	378	36	1	378	10	408	3.0e-75	275	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
639002695	272	51.08	1	271	1	269	1.0e-81	296	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
639002696	900	45.05	25	883	7	857	0.0e+00	814	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
639002697	261	55.51	1	251	1	253	2.0e-98	351	COG0024	Methionine aminopeptidase	255
639002698	256	60	1	225	1	224	3.0e-93	334	COG0052	Ribosomal protein S2	252
639002699	295	51.85	1	294	2	296	3.0e-92	331	COG0264	Translation elongation factor EF-Ts	296
639002700	239	65.53	4	237	3	237	5.0e-88	317	COG0528	Uridylate kinase	238
639002701	185	58.38	1	185	3	187	5.0e-65	240	COG0233	Ribosome recycling factor	187
639002702	256	49.79	4	244	3	243	9.0e-83	299	COG0020	Undecaprenyl pyrophosphate synthase	245
639002703	262	29.08	1	251	16	254	3.0e-23	102	COG0575	CDP-diglyceride synthetase	265
639002704	397	53.54	1	395	1	385	0.0e+00	503	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
639002706	758	39.48	1	758	3	766	0.0e+00	608	COG4775	Outer membrane protein assembly factor BamA	766
639002707	176	29.38	13	169	10	169	9.0e-18	83.5	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
639002708	354	50.45	8	340	5	338	2.0e-94	339	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
639002709	149	48	1	148	4	145	3.0e-38	150	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
639002710	256	56.47	2	256	6	260	1.0e-97	349	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
639002711	379	46.07	1	378	1	380	2.0e-109	389	COG0763	Lipid A disaccharide synthetase	381
639002712	218	54.69	15	201	3	194	9.0e-58	216	COG0164	Ribonuclease HII	199
639002713	1174	50.86	5	1159	4	1130	0.0e+00	1298	COG0587	DNA polymerase III, alpha subunit	1139
639002714	319	65.3	3	319	1	317	0.0e+00	484	COG0825	Acetyl-CoA carboxylase alpha subunit	317
639002715	446	33.82	24	282	26	296	4.0e-38	152	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
639002716	557	64.64	2	542	1	533	0.0e+00	872	COG0504	CTP synthase (UTP-ammonia lyase)	533
639002717	281	60.66	6	277	7	278	1.0e-115	409	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
639002718	430	63.85	1	426	1	423	0.0e+00	614	COG0148	Enolase	423
639002719	93	39.78	1	93	24	116	3.0e-15	73.4	COG2919	Cell division protein FtsB	117
639002720	241	48.26	9	236	5	230	4.0e-61	228	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
639002721	161	58.33	3	158	1	156	2.0e-56	211	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
639002722	186	38.8	3	182	5	182	1.0e-32	133	COG2840	DNA-nicking endonuclease, Smr domain	184
639002723	249	57.14	1	246	1	252	4.0e-85	307	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
639002724	220	49.76	15	220	1	206	2.0e-56	212	COG2518	Protein-L-isoaspartate O-methyltransferase	209
639002725	194	32.1	5	166	2	161	3.0e-21	94.9	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
639002727	356	43.41	27	355	9	342	2.0e-79	289	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
639002728	124	38.74	15	123	18	127	8.0e-24	102	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
639002729	401	42.97	15	397	5	391	1.0e-106	380	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
639002730	436	50.61	1	319	1	328	9.0e-101	361	COG0460	Homoserine dehydrogenase	333
639002731	379	43.49	6	377	50	411	3.0e-95	342	COG0498	Threonine synthase	411
639002732	346	25.09	67	337	51	314	5.0e-24	105	COG4255	Uncharacterized protein	318
639002733	566	41.07	26	542	4	491	7.0e-108	384	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
639002736	700	36.71	149	571	16	387	4.0e-77	283	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
639002737	882	36.77	1	872	5	859	0.0e+00	634	COG0308	Aminopeptidase N	859
639002738	286	24.9	33	275	34	291	7.0e-13	68.1	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
639002740	254	38.25	1	247	1	251	3.0e-57	215	COG1291	Flagellar motor component MotA	266
639002741	312	28.21	10	288	5	243	1.0e-37	150	COG1360	Flagellar motor protein MotB	244
639002747	239	32.1	11	239	1	242	2.0e-35	142	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
639002751	418	77.99	1	418	4	420	0.0e+00	721	COG1158	Transcription termination factor Rho	422
639002752	435	36.7	3	435	12	440	7.0e-84	304	COG2067	Long-chain fatty acid transport protein	440
639002753	162	41.36	1	153	8	167	5.0e-36	143	COG0262	Dihydrofolate reductase	167
639002757	277	66.67	1	277	3	268	7.0e-117	413	COG0207	Thymidylate synthase	268
639002758	268	46.72	1	257	5	275	4.0e-67	248	COG0682	Prolipoprotein diacylglyceryltransferase	287
639002759	392	35.1	12	382	19	407	4.0e-64	238	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
639002760	438	37.92	23	287	1	264	1.0e-58	220	COG0548	Acetylglutamate kinase	265
639002760	438	48.57	292	431	1	140	2.0e-35	143	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
639002761	316	35.78	83	298	45	256	1.0e-38	154	COG2992	Uncharacterized FlgJ-related protein	262
639002762	152	53.95	1	152	2	150	6.0e-53	199	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
639002763	210	37.24	1	196	2	190	3.0e-36	145	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
639002765	267	36.03	18	263	4	244	1.0e-31	130	COG1587	Uroporphyrinogen-III synthase	248
639002766	104	36.17	2	94	1	94	2.0e-14	70.3	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
639002768	192	31.25	1	175	4	176	7.0e-20	90.4	COG3079	Uncharacterized conserved protein YgfB, UPF0149 family	186
639002769	443	31.91	20	438	1	384	7.0e-65	241	COG0006	Xaa-Pro aminopeptidase	384
639002770	417	38.48	6	397	2	387	5.0e-65	241	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
639002771	396	39.85	7	389	4	384	2.0e-64	239	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
639002772	361	49.47	1	357	4	373	2.0e-104	372	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
639002773	130	61.24	1	128	2	130	1.0e-41	161	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
639002774	457	37.58	1	450	10	447	2.0e-117	416	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
639002775	166	57.59	1	158	1	158	2.0e-62	231	COG2077	Peroxiredoxin	158
639002776	483	50.83	1	480	7	482	0.0e+00	591	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
639002777	313	26.57	36	306	26	311	2.0e-32	133	COG0524	Sugar or nucleoside kinase, ribokinase family	311
639002779	354	23.78	22	164	2	134	3.0e-13	69.6	COG3415	Transposase	138
639002781	99	40.66	4	92	6	96	6.0e-16	75.7	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
639002783	275	48.12	6	270	4	265	5.0e-68	251	COG0345	Pyrroline-5-carboxylate reductase	266
639002784	345	64.74	1	345	3	348	0.0e+00	531	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
639002785	375	64.69	1	371	5	375	0.0e+00	568	COG5008	Tfp pilus assembly protein, ATPase PilU	375
639002786	429	39.48	6	427	5	424	2.0e-101	363	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
639002787	322	48.43	5	313	1	313	6.0e-100	357	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
639002788	170	48.15	31	160	33	167	3.0e-39	154	COG2065	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	179
639002789	143	36.88	4	143	2	140	3.0e-32	130	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
639002790	187	54.5	1	187	7	194	2.0e-60	225	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
639002791	283	20.3	13	275	2	242	2.0e-09	56.7	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
639002792	320	40.31	2	314	1	316	8.0e-67	247	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
639002796	184	30.82	26	184	5	162	2.0e-25	109	COG0835	Chemotaxis signal transduction protein	165
639002797	575	34.47	218	567	61	408	1.0e-39	158	COG0840	Methyl-accepting chemotaxis protein	408
639002798	1936	31.35	1034	1786	5	707	3.0e-120	427	COG0643	Chemotaxis protein histidine kinase CheA	716
639002799	157	20.3	18	147	27	151	1.0e-05	42.6	COG0835	Chemotaxis signal transduction protein	165
639002800	473	55.22	9	465	2	420	0.0e+00	627	COG0499	S-adenosylhomocysteine hydrolase	420
639002801	386	69.41	1	386	1	388	0.0e+00	673	COG0192	S-adenosylmethionine synthetase	388
639002802	664	60.51	1	664	3	662	0.0e+00	1030	COG0021	Transketolase	663
639002803	338	61.4	4	331	1	327	0.0e+00	462	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
639002804	391	53.62	1	390	2	394	0.0e+00	487	COG0126	3-phosphoglycerate kinase	395
639002806	483	46.95	1	474	3	477	0.0e+00	505	COG0469	Pyruvate kinase	477
639002807	299	33.68	14	295	2	245	5.0e-62	231	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
639002808	182	49.38	9	168	4	164	6.0e-49	186	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
639002809	249	50.79	182	244	3	65	3.0e-14	72.7	COG2771	DNA-binding transcriptional regulator, CsgD family	65
639002810	185	42.2	1	172	20	189	6.0e-37	147	COG3916	N-acyl-L-homoserine lactone synthetase	209
639002812	224	59.01	1	222	1	220	3.0e-86	311	COG0036	Pentose-5-phosphate-3-epimerase	220
639002813	229	43.64	2	221	1	218	6.0e-49	187	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
639002814	495	48.23	18	494	1	462	0.0e+00	496	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
639002815	197	62.83	1	191	3	189	3.0e-81	294	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
639002816	334	52.31	3	327	14	338	2.0e-109	389	COG0547	Anthranilate phosphoribosyltransferase	338
639002817	270	52.71	11	268	1	254	2.0e-81	295	COG0134	Indole-3-glycerol phosphate synthase	254
639002818	331	19.32	19	268	10	250	2.0e-09	57.3	COG0685	5,10-methylenetetrahydrofolate reductase	291
639002820	479	37.82	14	477	1	458	1.0e-87	317	COG0277	FAD/FMN-containing dehydrogenase	459
639002824	223	45.74	1	220	1	218	8.0e-48	183	COG4122	Predicted O-methyltransferase YrrM	219
639002825	279	32.97	19	279	1	271	5.0e-28	118	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
639002827	60	53.7	7	60	1	54	8.0e-14	68.7	COG1773	Rubredoxin	55
639002828	211	43.54	5	211	1	208	3.0e-44	172	COG0352	Thiamine monophosphate synthase	211
639002829	426	61.18	3	426	6	429	0.0e+00	575	COG0001	Glutamate-1-semialdehyde aminotransferase	432
639002830	457	39.61	2	451	9	459	1.0e-125	443	COG0773	UDP-N-acetylmuramate-alanine ligase	459
639002832	411	46.81	95	375	2	283	9.0e-91	327	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
639002833	421	25.58	1	387	1	347	7.0e-47	181	COG0205	6-phosphofructokinase	347
639002834	667	46.66	1	667	3	700	0.0e+00	583	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
639002835	182	58.9	13	175	12	171	1.0e-52	199	COG0221	Inorganic pyrophosphatase	171
639002836	191	57.14	1	187	1	184	4.0e-58	217	COG2096	Cob(I)alamin adenosyltransferase	184
639002838	307	38.59	1	290	2	299	2.0e-64	239	COG2264	Ribosomal protein L11 methylase PrmA	300
639002839	100	44.9	1	98	1	97	1.0e-21	95	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
639002840	518	60.73	1	518	2	515	0.0e+00	695	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
639002841	432	53.85	1	428	1	427	0.0e+00	555	COG0151	Phosphoribosylamine-glycine ligase	428
639002843	183	51.1	1	180	4	185	3.0e-51	194	COG1704	Uncharacterized conserved protein	185
639002844	344	30.53	29	341	1	296	2.0e-30	126	COG0501	Zn-dependent protease with chaperone function	302
639002846	298	45.55	2	292	1	285	1.0e-67	249	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
639002847	228	33.02	14	225	7	203	6.0e-38	150	COG0560	Phosphoserine phosphatase	212
639002849	755	45.12	1	755	1	756	0.0e+00	738	COG3605	Signal transduction protein containing GAF and PtsI domains	756
639002850	72	50	6	63	1	58	4.0e-12	63	COG2906	Bacterioferritin-associated ferredoxin	63
639002857	258	28.63	20	249	3	257	5.0e-36	144	COG3344	Retron-type reverse transcriptase	328
639002863	612	17.99	144	542	22	425	2.0e-10	61.5	COG5421	Transposase	480
639002866	405	22.33	10	400	16	391	3.0e-14	73.1	COG3919	Predicted ATP-dependent carboligase, ATP-grasp superfamily	415
639002870	461	22.94	35	454	8	434	3.0e-45	176	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
639002871	389	24.6	34	388	4	381	1.0e-36	147	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639002872	412	31.08	83	404	69	380	1.0e-32	134	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639002873	646	32.13	1	602	1	519	3.0e-110	392	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
639002874	404	31.12	11	386	1	381	9.0e-35	141	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639002879	390	37.89	23	388	6	381	2.0e-88	319	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
639002881	299	28.63	61	296	15	251	2.0e-28	119	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
639002882	518	22.86	8	452	14	448	5.0e-31	129	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
639002883	199	29.21	1	197	12	206	1.0e-20	93.3	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
639002884	918	20.81	3	212	6	226	2.0e-10	61.9	COG3063	Tfp pilus assembly protein PilF	250
639002885	455	48.46	7	448	6	456	2.0e-126	445	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
639002887	490	33.46	1	262	9	269	9.0e-34	138	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
639002890	263	21.24	47	225	21	209	6.0e-10	58	COG3916	N-acyl-L-homoserine lactone synthetase	209
639002891	328	19.81	20	314	12	315	5.0e-11	62	COG3239	Fatty acid desaturase	343
639002898	439	31.75	35	382	24	371	4.0e-44	172	COG5659	SRSO17 transposase	385
639002901	138	26.52	1	129	2	128	2.0e-07	48.4	COG4113	Predicted nucleic acid-binding protein, contains PIN domain	134
639002902	207	53.76	2	186	1	186	6.0e-68	250	COG2818	3-methyladenine DNA glycosylase Tag	188
639002903	510	48.52	1	498	10	510	0.0e+00	496	COG0578	Glycerol-3-phosphate dehydrogenase	532
639002905	190	39.27	1	189	1	174	7.0e-35	140	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
639002906	115	39.22	4	105	3	99	2.0e-19	87.4	COG2863	Cytochrome c553	121
639002907	108	35.92	4	105	3	99	2.0e-15	73.9	COG2863	Cytochrome c553	121
639002908	90	42.86	1	90	1	91	4.0e-21	93	COG1254	Acylphosphatase	92
639002910	115	43.48	1	115	1	115	1.0e-30	124	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
639002912	378	22.57	20	304	8	284	2.0e-19	90.5	COG3249	Uncharacterized protein	343
639002913	350	58.89	10	349	4	345	0.0e+00	461	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
639002914	223	51.5	6	205	1	200	3.0e-68	251	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
639002915	187	40.53	3	186	2	180	7.0e-55	206	COG0717	Deoxycytidine triphosphate deaminase	183
639002916	400	39.13	82	352	1	265	3.0e-56	212	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
639002917	174	39.52	7	170	4	169	2.0e-35	141	COG0703	Shikimate kinase	172
639002918	92	26.67	8	67	5	63	6.0e-06	42.6	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
639002919	1108	18.92	28	675	26	705	7.0e-26	113	COG0308	Aminopeptidase N	859
639002919	1108	29.09	715	1025	100	425	1.0e-25	112	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
639002922	206	24.63	5	204	4	204	4.0e-25	108	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
639002923	495	23	23	486	22	486	9.0e-30	125	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
639002926	655	42.2	9	625	2	624	0.0e+00	463	COG1297	Uncharacterized membrane protein, oligopeptide transporter (OPT) family	624
639002928	390	37.92	151	387	1	234	9.0e-52	197	COG1018	Ferredoxin-NADP reductase	266
639002928	390	52	2	151	1	150	2.0e-56	213	COG1017	Hemoglobin-like flavoprotein	150
639002929	294	28.68	2	272	4	267	1.0e-26	114	COG3336	Cytochrome c oxidase assembly factor CtaG	299
639002930	197	35.29	8	193	17	203	1.0e-35	143	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
639002931	562	51.32	1	561	7	575	0.0e+00	703	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
639002932	327	43.13	20	326	1	310	1.0e-77	283	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
639002933	200	22.65	15	173	49	226	1.0e-08	53	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
639002934	387	50.81	7	376	8	366	5.0e-125	441	COG2021	Homoserine acetyltransferase	368
639002936	183	37.85	1	173	14	189	5.0e-39	153	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
639002937	332	41.34	1	323	1	353	7.0e-74	271	COG1858	Cytochrome c peroxidase	364
639002945	570	38.01	14	568	17	552	8.0e-103	368	COG0659	Sulfate permease or related transporter, MFS superfamily	554
639002947	485	44.57	19	449	2	432	6.0e-118	418	COG4623	Membrane-bound lytic murein transglycosylase MltF	473
639002950	394	23.67	113	392	83	336	2.0e-22	100	COG0642	Signal transduction histidine kinase	336
639002953	181	32.43	1	181	1	177	6.0e-17	80.4	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
639002955	229	46.72	1	223	1	228	3.0e-54	204	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
639002956	451	29.75	144	450	17	331	8.0e-34	138	COG0642	Signal transduction histidine kinase	336
639002957	278	30.51	3	270	1	295	4.0e-24	105	COG0524	Sugar or nucleoside kinase, ribokinase family	311
639002958	148	47.93	17	137	2	118	9.0e-24	102	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
639002959	1171	29.39	484	1170	117	866	1.0e-86	315	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
639002959	1171	34.03	1	188	3	193	2.0e-39	158	COG4279	Uncharacterized conserved protein, contains Zn finger domain	266
639002964	1220	50.65	11	1220	29	1227	0.0e+00	1455	COG5013	Nitrate reductase alpha subunit	1227
639002967	145	44	1	124	15	139	6.0e-28	116	COG1959	DNA-binding transcriptional regulator, IscR family	150
639002968	384	41.82	2	383	15	396	1.0e-62	234	COG3213	Uncharacterized protein involved in response to NO	396
639002969	273	35.82	134	267	1	132	2.0e-26	113	COG2343	Uncharacterized conserved protein, DUF427 family	132
639002971	347	56.4	1	340	1	344	0.0e+00	479	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
639002972	370	60.61	5	366	1	363	0.0e+00	490	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
639002973	130	49.47	13	106	1	95	2.0e-24	104	COG1862	Preprotein translocase subunit YajC	97
639002974	619	48.08	75	619	1	506	0.0e+00	476	COG0342	Preprotein translocase subunit SecD	506
639002975	309	50.65	1	304	1	305	5.0e-82	297	COG0341	Preprotein translocase subunit SecF	305
639002976	262	49.22	1	252	4	259	1.0e-72	266	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
639002977	243	47.7	4	242	3	236	7.0e-66	243	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
639002978	277	62.64	1	174	3	176	2.0e-67	249	COG1045	Serine acetyltransferase	194
639002979	429	50.13	8	396	2	386	2.0e-124	439	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
639002981	107	50	1	107	3	110	3.0e-34	136	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
639002982	140	55.97	1	134	2	135	5.0e-53	199	COG0105	Nucleoside diphosphate kinase	135
639002983	378	55.56	17	365	1	349	8.0e-125	440	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
639002984	257	35.74	11	244	8	242	5.0e-46	177	COG3063	Tfp pilus assembly protein PilF	250
639002985	363	21.57	23	328	4	284	4.0e-20	92.5	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
639002986	424	47.55	5	423	4	429	0.0e+00	460	COG0124	Histidyl-tRNA synthetase	429
639002987	213	34.13	1	208	1	207	7.0e-30	123	COG2976	Putative negative regulator of RcsB-dependent stress response	207
639002988	383	26.59	10	331	12	356	6.0e-30	125	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
639002989	253	44.27	1	240	1	252	3.0e-56	212	COG3332	Uncharacterized conserved protein, contains NRDE domain	270
639002990	218	43.44	1	217	1	178	6.0e-46	177	COG0563	Adenylate kinase or related kinase	178
639002991	453	43.79	1	450	2	433	3.0e-105	376	COG1030	Membrane-bound serine protease (ClpP class)	436
639002992	194	51.85	6	194	26	214	2.0e-61	228	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
639002993	433	27.98	64	414	88	447	1.0e-40	161	COG5002	Signal transduction histidine kinase	459
639002994	358	38.44	1	331	6	318	5.0e-65	241	COG0226	ABC-type phosphate transport system, periplasmic component	318
639002995	330	44.72	10	326	1	310	3.0e-74	272	COG0573	ABC-type phosphate transport system, permease component	310
639002996	277	45.77	1	277	6	289	2.0e-64	239	COG0581	ABC-type phosphate transport system, permease component	292
639002997	301	67.61	55	301	8	253	6.0e-125	440	COG1117	ABC-type phosphate transport system, ATPase component	253
639002998	240	35.17	3	238	2	237	1.0e-39	156	COG0704	Phosphate uptake regulator	240
639002999	303	53.42	1	297	4	309	6.0e-117	413	COG0078	Ornithine carbamoyltransferase	310
639003000	398	49.2	5	377	17	388	0.0e+00	470	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
639003001	195	51.74	1	195	2	200	3.0e-68	251	COG0605	Superoxide dismutase	204
639003002	386	41.18	193	359	4	173	5.0e-36	145	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
639003003	277	43.83	2	235	18	249	3.0e-51	195	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
639003005	327	32.14	1	326	1	329	2.0e-50	192	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
639003006	240	31.94	24	237	14	213	3.0e-30	125	COG1451	Predicted metal-dependent hydrolase	223
639003007	612	18.46	144	542	22	425	1.0e-16	81.5	COG5421	Transposase	480
639003008	605	65.61	1	602	1	601	0.0e+00	948	COG1217	Predicted membrane GTPase involved in stress response	603
639003012	277	41.94	15	268	7	284	1.0e-65	243	COG1469	GTP cyclohydrolase FolE2	289
639003013	127	41.09	4	126	2	127	9.0e-25	105	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
639003014	298	36.72	4	298	3	322	5.0e-65	241	COG0142	Geranylgeranyl pyrophosphate synthase	322
639003015	83	51.47	10	77	11	78	2.0e-11	60.7	COG1722	Exonuclease VII small subunit	81
639003016	630	46.87	1	629	2	633	0.0e+00	823	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
639003017	747	43.75	1	738	1	739	0.0e+00	777	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
639003018	693	31.09	444	681	4	240	9.0e-45	175	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
639003018	693	31.21	259	430	12	181	4.0e-22	100	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
639003020	339	47.4	14	339	13	339	1.0e-103	369	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
639003021	189	49.62	1	131	1	131	5.0e-41	160	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
639003022	323	55.31	4	323	6	322	5.0e-104	371	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
639003023	299	30.4	25	293	4	239	3.0e-48	185	COG0688	Phosphatidylserine decarboxylase	239
639003024	367	58.86	2	361	1	366	0.0e+00	516	COG0082	Chorismate synthase	369
639003026	467	55.13	3	467	2	422	0.0e+00	592	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
639003027	216	55.19	1	212	1	191	2.0e-77	282	COG0066	3-isopropylmalate dehydratase small subunit	191
639003028	362	53.31	1	358	2	346	3.0e-116	412	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
639003029	370	28.46	1	368	1	334	4.0e-83	301	COG0136	Aspartate-semialdehyde dehydrogenase	334
639003030	871	25.88	3	871	15	755	2.0e-46	181	COG3170	Tfp pilus assembly protein FimV	755
639003031	284	51.74	25	283	1	259	1.0e-86	313	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
639003032	211	41.63	2	205	1	208	5.0e-55	207	COG0135	Phosphoribosylanthranilate isomerase	208
639003033	138	32.81	1	123	1	128	1.0e-12	65.4	COG3791	Uncharacterized conserved protein	133
639003034	819	45.85	534	786	2	248	2.0e-72	267	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
639003035	312	24.65	30	311	1	274	4.0e-31	128	COG2301	Citrate lyase beta subunit	283
639003039	191	60.96	2	188	1	182	8.0e-63	233	COG2310	Stress response protein SCP2	182
639003040	346	22.53	51	343	1	253	2.0e-30	127	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
639003041	150	39.69	20	150	14	144	2.0e-27	114	COG3793	Tellurite resistance protein	144
639003042	397	38.17	1	166	2	182	5.0e-28	119	COG2310	Stress response protein SCP2	182
639003042	397	51.74	200	397	1	200	3.0e-65	242	COG4110	Uncharacterized protein involved in tellurium resistance	200
639003043	194	41.44	2	180	1	172	2.0e-39	155	COG2310	Stress response protein SCP2	182
639003044	147	46.39	4	147	2	167	5.0e-37	146	COG0629	Single-stranded DNA-binding protein	167
639003045	352	42.77	16	346	7	344	1.0e-86	313	COG1816	Adenosine deaminase	345
639003046	439	31.48	35	382	24	371	1.0e-42	167	COG5659	SRSO17 transposase	385
639003047	156	39.04	1	145	6	147	2.0e-32	131	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
639003048	490	22.69	210	469	1	234	2.0e-37	150	COG0775	Nucleoside phosphorylase	234
639003049	573	45.34	4	398	3	387	1.0e-122	433	COG2046	ATP sulfurylase (sulfate adenylyltransferase)	397
639003049	573	52.2	391	572	19	197	5.0e-60	225	COG0529	Adenylylsulfate kinase or related kinase	197
639003050	399	21.21	24	384	30	386	3.0e-18	86.8	COG2814	Predicted arabinose efflux permease, MFS family	394
639003051	966	64.86	1	942	3	935	0.0e+00	1472	COG0178	Excinuclease UvrABC ATPase subunit	935
639003052	326	30.06	5	326	1	312	6.0e-63	234	COG0039	Malate/lactate dehydrogenase	313
639003053	243	35.47	1	239	4	265	5.0e-48	184	COG1912	S-adenosylmethionine hydrolase (SAM-hydroxide adenosyltransferase)	268
639003054	132	72.41	1	116	1	116	5.0e-45	173	COG0203	Ribosomal protein L17	116
639003055	333	53.92	8	326	1	317	2.0e-96	345	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
639003056	206	60.1	1	206	1	205	5.0e-60	224	COG0522	Ribosomal protein S4 or related protein	205
639003057	129	66.67	1	129	1	129	2.0e-48	184	COG0100	Ribosomal protein S11	129
639003058	118	66.39	1	118	1	119	4.0e-40	156	COG0099	Ribosomal protein S13	121
639003060	421	50.85	1	405	26	432	1.0e-120	426	COG0201	Preprotein translocase subunit SecY	436
639003061	145	48.32	1	143	1	149	1.0e-28	119	COG0200	Ribosomal protein L15	152
639003062	62	47.27	7	61	1	55	1.0e-12	64.4	COG1841	Ribosomal protein L30/L7E	55
639003063	167	60.12	6	167	18	180	4.0e-51	194	COG0098	Ribosomal protein S5	181
639003064	117	50	1	117	6	125	9.0e-26	108	COG0256	Ribosomal protein L18	125
639003065	177	52.54	1	176	1	176	2.0e-58	218	COG0097	Ribosomal protein L6P/L9E	178
639003066	131	60.61	1	131	1	132	1.0e-45	174	COG0096	Ribosomal protein S8	132
639003067	101	62.3	41	101	1	61	5.0e-16	76	COG0199	Ribosomal protein S14	61
639003068	179	63.48	1	178	1	178	2.0e-71	261	COG0094	Ribosomal protein L5	180
639003069	106	49.06	1	105	2	104	5.0e-19	86.1	COG0198	Ribosomal protein L24	104
639003070	122	69.67	1	122	1	122	1.0e-47	181	COG0093	Ribosomal protein L14	122
639003071	68	54.41	1	68	20	87	1.0e-19	88.3	COG0186	Ribosomal protein S17	87
639003072	67	57.38	2	62	4	64	1.0e-09	54.9	COG0255	Ribosomal protein L29	69
639003073	138	67.65	1	134	2	137	2.0e-46	178	COG0197	Ribosomal protein L16/L10AE	146
639003074	224	63.18	12	211	1	201	2.0e-76	278	COG0092	Ribosomal protein S3	233
639003075	110	63.3	1	109	9	117	6.0e-32	129	COG0091	Ribosomal protein L22	120
639003076	91	69.57	1	91	1	92	3.0e-33	133	COG0185	Ribosomal protein S19	93
639003077	274	63.5	1	273	1	274	2.0e-103	368	COG0090	Ribosomal protein L2	275
639003078	99	49.46	7	98	2	94	4.0e-23	99.5	COG0089	Ribosomal protein L23	94
639003079	201	46	7	201	12	211	4.0e-44	171	COG0088	Ribosomal protein L4	214
639003080	219	54.63	3	217	2	217	2.0e-69	255	COG0087	Ribosomal protein L3	218
639003081	104	75.25	4	104	3	103	4.0e-38	149	COG0051	Ribosomal protein S10	104
639003082	396	82.07	1	396	1	394	0.0e+00	707	COG0050	Translation elongation factor EF-Tu, a GTPase	394
639003083	697	66.52	1	695	1	690	0.0e+00	1010	COG0480	Translation elongation factor EF-G, a GTPase	697
639003084	156	60.81	2	149	1	148	3.0e-51	194	COG0049	Ribosomal protein S7	148
639003086	1425	51.05	21	852	7	806	0.0e+00	885	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
639003088	126	68.8	2	126	1	124	3.0e-25	107	COG0222	Ribosomal protein L7/L12	124
639003089	175	37.36	1	173	1	174	1.0e-35	142	COG0244	Ribosomal protein L10	175
639003090	231	59.65	1	227	1	228	8.0e-78	283	COG0081	Ribosomal protein L1	228
639003091	146	74.47	2	142	1	140	2.0e-56	211	COG0080	Ribosomal protein L11	141
639003092	177	53.41	1	176	1	176	3.0e-52	198	COG0250	Transcription antitermination factor NusG	178
639003093	125	37.5	48	119	2	73	2.0e-10	58.1	COG0690	Preprotein translocase subunit SecE	73
639003095	396	82.07	1	396	1	394	0.0e+00	707	COG0050	Translation elongation factor EF-Tu, a GTPase	394
639003101	400	21.16	5	372	8	366	4.0e-15	76.2	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
639003102	613	23.03	69	572	96	520	5.0e-40	159	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
639003108	317	28.91	63	315	1	228	2.0e-19	90.2	COG3039	Transposase and inactivated derivatives, IS5 family	230
639003109	450	17.06	10	420	5	421	9.0e-09	55.2	COG3307	O-antigen ligase	424
639003110	399	20.84	1	388	1	379	1.0e-18	87.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639003112	479	18.46	1	454	37	480	3.0e-14	73.6	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
639003113	365	31.49	78	364	105	378	8.0e-33	134	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639003116	317	28.91	63	315	1	228	6.0e-20	91.7	COG3039	Transposase and inactivated derivatives, IS5 family	230
639003121	155	37.98	7	130	4	132	6.0e-27	113	COG0615	Glycerol-3-phosphate cytidylyltransferase, cytidylyltransferase family	140
639003127	603	41.46	17	590	1	565	1.0e-125	444	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
639003128	314	36.16	4	310	2	305	5.0e-66	244	COG1893	Ketopantoate reductase	307
639003129	733	35.03	21	713	34	748	0.0e+00	471	COG1444	tRNA(Met) C34 N-acetyltransferase TmcA	758
639003131	185	70.88	1	182	1	182	6.0e-83	299	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
639003133	352	50.66	47	350	18	320	5.0e-84	304	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
639003134	251	32.07	14	243	12	244	2.0e-33	136	COG0121	Predicted glutamine amidotransferase	252
639003135	388	25.76	189	388	69	312	3.0e-19	89.8	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
639003137	350	36.36	41	347	1	263	3.0e-65	242	COG1830	Fructose-bisphosphate aldolase class Ia, DhnA family	265
639003138	530	61.62	31	525	1	495	0.0e+00	651	COG3067	Na+/H+ antiporter NhaB	516
639003139	278	51.27	6	276	5	279	5.0e-87	314	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
639003140	126	19.57	1	116	1	138	2.0e-06	45.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
639003141	416	40.1	1	409	1	406	1.0e-89	323	COG1228	Imidazolonepropionase or related amidohydrolase	406
639003142	569	72.66	8	563	4	559	0.0e+00	937	COG2987	Urocanate hydratase	561
639003143	454	27.62	1	442	3	421	7.0e-55	208	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
639003149	201	23.73	16	190	4	177	6.0e-07	47.7	COG0558	Phosphatidylglycerophosphate synthase	192
639003152	248	30.68	1	245	4	232	3.0e-32	131	COG1213	Choline kinase	239
639003153	550	32.08	10	299	3	289	1.0e-60	227	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
639003154	382	23.75	1	160	4	161	4.0e-17	82.7	COG4032	Sulfopyruvate decarboxylase, TPP-binding subunit (coenzyme M biosynthesis)	172
639003155	345	36.06	1	341	6	357	6.0e-71	261	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
639003157	506	22.19	22	387	31	420	1.0e-30	127	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
639003160	382	30.58	1	381	2	398	3.0e-70	259	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
639003161	326	57.1	3	325	1	324	1.0e-130	459	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
639003162	364	40.85	20	360	4	358	3.0e-92	332	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
639003163	286	37.11	3	285	29	298	8.0e-38	150	COG0501	Zn-dependent protease with chaperone function	302
639003165	446	28.74	15	418	17	409	4.0e-49	189	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
639003166	675	37.8	17	507	22	519	9.0e-107	381	COG2936	Predicted acyl esterase	563
639003171	587	27.44	4	216	3	197	9.0e-18	85.6	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
639003173	1656	38.29	258	522	1	268	1.0e-66	249	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
639003180	322	33.01	11	309	1	303	6.0e-49	188	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
639003184	395	40.99	4	395	1	392	3.0e-77	282	COG0183	Acetyl-CoA acetyltransferase	392
639003188	663	29.8	352	643	3	296	3.0e-21	97.1	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
639003189	575	29.69	2	573	16	592	7.0e-83	301	COG0729	Outer membrane translocation and assembly module TamA	594
639003190	1321	22.01	4	1317	10	1274	4.0e-118	420	COG2911	Autotransporter translocation and assembly factor TamB	1278
639003193	421	36.45	4	420	6	404	3.0e-76	279	COG1301	Na+/H+-dicarboxylate symporter	415
639003194	443	26.85	4	140	6	154	3.0e-07	50.4	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
639003197	149	39.01	13	148	6	146	7.0e-22	96.6	COG0071	Molecular chaperone IbpA, HSP20 family	146
639003198	185	50	4	183	15	185	5.0e-51	193	COG1704	Uncharacterized conserved protein	185
639003199	248	37.22	5	248	6	271	1.0e-45	176	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
639003200	205	36.06	4	205	6	213	2.0e-34	138	COG3762	Uncharacterized membrane protein	213
639003206	729	43.13	259	727	106	545	3.0e-129	456	COG2225	Malate synthase	545
639003207	917	61.88	3	912	1	861	0.0e+00	1214	COG1048	Aconitase A	861
639003208	204	38	7	202	6	205	3.0e-41	161	COG2915	Regulator of phage lambda lysogenization HflD, binds to CII and stimulates its degradation	207
639003209	374	50.56	4	361	3	355	1.0e-121	429	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
639003210	150	29.51	1	121	4	124	7.0e-10	56.6	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
639003211	326	31.4	14	302	2	290	4.0e-38	152	COG0583	DNA-binding transcriptional regulator, LysR family	297
639003212	429	68.63	10	425	10	433	0.0e+00	607	COG2224	Isocitrate lyase	433
639003213	106	53.12	11	106	12	107	2.0e-30	124	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
639003214	755	46.66	1	750	1	785	0.0e+00	850	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
639003215	72	66.67	1	72	1	72	8.0e-23	98.3	COG0361	Translation initiation factor IF-1	75
639003216	240	42.92	4	237	2	241	2.0e-59	222	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
639003217	250	53.67	15	231	2	219	8.0e-75	273	COG2360	Leu/Phe-tRNA-protein transferase	221
639003218	297	48.76	3	285	103	384	1.0e-84	306	COG3146	Predicted N-acyltransferase	387
639003221	199	32.8	6	189	22	208	1.0e-31	130	COG2834	Outer membrane lipoprotein-sorting protein	211
639003222	435	58.12	7	431	13	436	0.0e+00	566	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
639003223	425	56.44	1	423	1	425	0.0e+00	545	COG0172	Seryl-tRNA synthetase	429
639003224	326	30.54	1	296	1	292	5.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
639003225	256	58.37	1	245	2	243	6.0e-84	303	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
639003226	234	30.32	24	234	15	233	3.0e-19	89.2	COG0670	Integral membrane protein, interacts with FtsH	233
639003228	191	24.14	1	167	2	165	1.0e-14	73.5	COG0622	Predicted phosphodiesterase	172
639003229	1294	35.78	38	956	7	844	0.0e+00	677	COG1643	HrpA-like RNA helicase	845
639003230	325	63.18	88	325	1	239	8.0e-93	334	COG1186	Protein chain release factor B	239
639003231	506	61.82	11	501	7	500	0.0e+00	700	COG1190	Lysyl-tRNA synthetase (class II)	502
639003232	364	22.99	4	333	5	361	6.0e-24	105	COG3240	Phospholipase/lecithinase/hemolysin	370
639003239	484	26.94	9	366	1	380	3.0e-38	153	COG0515	Serine/threonine protein kinase	384
639003242	245	26.67	1	239	1	228	6.0e-36	144	COG1018	Ferredoxin-NADP reductase	266
639003246	330	28.11	5	329	4	314	2.0e-38	153	COG0451	Nucleoside-diphosphate-sugar epimerase	314
639003247	234	38.36	10	222	17	235	5.0e-29	121	COG4089	Uncharacterized membrane protein	235
639003248	841	29.1	29	820	64	813	4.0e-104	372	COG3264	Small-conductance mechanosensitive channel	835
639003249	348	24.81	93	337	79	316	4.0e-21	95.7	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
639003250	677	34.29	18	553	23	563	4.0e-103	369	COG2936	Predicted acyl esterase	563
639003252	266	41.67	26	264	1	217	7.0e-50	190	COG1878	Kynurenine formamidase	218
639003255	565	49.9	14	509	11	498	0.0e+00	505	COG1292	Choline-glycine betaine transporter	537
639003259	413	28.12	1	406	18	402	3.0e-42	166	COG2223	Nitrate/nitrite transporter NarK	417
639003265	803	40.16	301	785	171	645	1.0e-123	437	COG1067	Predicted ATP-dependent protease	647
639003267	266	37.64	7	263	1	250	2.0e-39	155	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
639003269	306	25.26	6	298	12	288	5.0e-36	145	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
639003270	521	53.89	28	514	16	498	0.0e+00	499	COG2986	Histidine ammonia-lyase	498
639003271	234	29.35	29	198	28	211	7.0e-28	117	COG2091	Phosphopantetheinyl transferase	223
639003273	363	48.86	6	349	1	349	7.0e-88	317	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
639003274	340	53.55	1	338	2	335	7.0e-112	397	COG3138	Arginine/ornithine N-succinyltransferase beta subunit	336
639003275	444	25.37	49	432	13	409	9.0e-33	134	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
639003276	478	33.05	1	226	2	237	2.0e-30	127	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
639003278	581	30.46	142	313	1	173	2.0e-17	84.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
639003278	581	47.11	330	571	2	241	9.0e-69	254	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
639003280	700	64.51	1	696	2	692	0.0e+00	985	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
639003281	89	59.55	1	89	1	89	1.0e-25	107	COG0184	Ribosomal protein S15P/S13E	89
639003282	303	39.67	1	302	4	271	1.0e-63	237	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
639003283	114	42.2	1	109	10	118	3.0e-25	107	COG0858	Ribosome-binding factor A	118
639003284	859	59.57	358	859	1	507	0.0e+00	627	COG0532	Translation initiation factor IF-2, a GTPase	509
639003285	500	48.47	160	354	1	190	9.0e-46	178	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
639003286	150	42.66	7	149	10	152	1.0e-38	152	COG0779	Ribosome maturation factor RimP	153
639003288	478	44	4	477	1	472	1.0e-94	341	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
639003289	501	52.09	1	501	5	490	0.0e+00	506	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
639003290	660	43.76	5	650	1	606	3.0e-127	449	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
639003291	101	58.42	1	101	1	100	6.0e-21	92.1	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
639003292	202	49.71	1	171	2	166	7.0e-27	113	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
639003293	162	39.16	2	162	1	161	4.0e-40	157	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
639003294	339	50	5	334	9	330	4.0e-93	335	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
639003295	798	37.43	12	752	1	688	0.0e+00	568	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
639003296	427	58.48	14	419	21	424	0.0e+00	619	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
639003297	167	49.04	11	167	5	157	8.0e-51	192	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
639003298	417	58.55	3	417	11	398	0.0e+00	595	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
639003299	240	40.48	1	210	6	169	3.0e-40	158	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
639003300	158	70.7	2	158	12	168	1.0e-76	278	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
639003301	118	55.93	1	118	4	121	3.0e-30	123	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
639003304	240	49.58	1	237	12	246	7.0e-72	263	COG0149	Triosephosphate isomerase	251
639003305	460	44.78	1	445	5	461	2.0e-113	402	COG1109	Phosphomannomutase	464
639003306	287	46.72	26	281	8	262	3.0e-67	249	COG0294	Dihydropteroate synthase	274
639003307	646	60.73	6	603	1	596	0.0e+00	788	COG0465	ATP-dependent Zn proteases	596
639003308	190	56.59	2	183	18	199	3.0e-62	231	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
639003310	158	51.63	6	158	1	151	2.0e-36	145	COG0782	Transcription elongation factor, GreA/GreB family	151
639003311	1073	69.44	13	408	1	393	0.0e+00	549	COG0458	Carbamoylphosphate synthase large subunit	400
639003312	390	53.81	2	381	1	368	0.0e+00	529	COG0505	Carbamoylphosphate synthase small subunit	368
639003313	317	37.95	1	302	2	293	8.0e-72	264	COG1131	ABC-type multidrug transport system, ATPase component	293
639003314	265	23.66	37	259	43	254	8.0e-11	60.9	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
639003315	449	38.37	6	402	12	401	2.0e-85	309	COG1488	Nicotinic acid phosphoribosyltransferase	405
639003317	200	57.14	4	199	3	198	5.0e-75	273	COG0353	Recombinational DNA repair protein RecR	198
639003318	109	50	3	106	2	105	2.0e-24	104	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
639003319	553	45.92	1	427	1	428	1.0e-129	457	COG2812	DNA polymerase III, gamma/tau subunits	515
639003322	167	26.51	2	162	5	169	2.0e-17	82	COG4970	Tfp pilus assembly protein FimT	181
639003323	167	33.56	16	151	7	152	1.0e-13	69.6	COG4967	Tfp pilus assembly protein PilV	162
639003324	345	23.47	1	288	1	285	2.0e-20	93.6	COG4966	Tfp pilus assembly protein PilW	318
639003325	182	30.1	4	178	9	191	4.0e-20	91.2	COG4726	Tfp pilus assembly protein PilX	196
639003326	1179	29.15	172	1179	64	1036	7.0e-126	445	COG3419	Tfp pilus assembly protein, tip-associated adhesin PilY1	1036
639003328	146	40	7	146	2	139	1.0e-29	122	COG4968	Tfp pilus assembly protein PilE	139
639003329	185	32.22	5	179	8	174	1.0e-17	82.8	COG4970	Tfp pilus assembly protein FimT	181
639003330	325	64.41	1	295	1	290	8.0e-119	420	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
639003331	157	46.71	9	157	15	162	7.0e-33	133	COG0597	Lipoprotein signal peptidase	167
639003332	940	48	2	934	1	933	0.0e+00	1179	COG0060	Isoleucyl-tRNA synthetase	933
639003333	325	50	15	320	1	304	1.0e-95	343	COG0196	FAD synthase	304
639003334	504	46.28	2	495	26	516	1.0e-103	370	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
639003336	379	52.3	7	374	3	369	3.0e-117	415	COG0263	Glutamate 5-kinase	369
639003337	347	57.35	1	347	1	346	0.0e+00	466	COG0536	GTPase involved in cell partioning and DNA repair	369
639003338	87	70.24	1	84	1	83	5.0e-30	122	COG0211	Ribosomal protein L27	87
639003339	107	55.34	1	103	1	103	5.0e-34	136	COG0261	Ribosomal protein L21	103
639003340	253	39.22	4	251	1	254	4.0e-65	241	COG0142	Geranylgeranyl pyrophosphate synthase	322
639003343	233	30.43	3	207	1	206	2.0e-29	123	COG0406	Broad specificity phosphatase PhoE	208
639003345	107	26.5	3	105	11	126	1.0e-05	41.9	COG2916	DNA-binding protein H-NS	128
639003351	432	54.61	6	428	1	408	0.0e+00	470	COG0593	Chromosomal replication initiation ATPase DnaA	408
639003352	366	39.78	1	366	1	364	1.0e-84	306	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
639003353	357	36.57	1	352	1	360	2.0e-73	269	COG1195	Recombinational DNA repair ATPase RecF	363
639003354	805	62.25	2	557	1	556	0.0e+00	902	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
639003355	250	31.94	23	228	3	212	8.0e-25	107	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
639003356	181	35.75	1	179	3	179	7.0e-40	156	COG0241	Histidinol phosphatase or a related phosphatase	181
639003357	702	46.76	6	698	4	689	0.0e+00	746	COG0751	Glycyl-tRNA synthetase, beta subunit	691
639003358	298	76.37	1	292	4	295	0.0e+00	531	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
639003360	471	47.16	4	471	2	443	0.0e+00	502	COG0174	Glutamine synthetase	443
639003362	352	45.92	1	348	1	355	1.0e-83	303	COG3852	Signal transduction histidine kinase, nitrogen specific	363
639003363	465	50.32	1	465	1	458	0.0e+00	527	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
639003364	309	40.79	28	301	12	283	5.0e-60	224	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
639003369	205	34.44	20	196	6	183	1.0e-35	143	COG1628	Endonuclease V homolog, UPF0215 family	185
639003370	169	56.21	13	164	2	153	2.0e-51	195	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
639003371	334	54.13	6	332	3	329	1.0e-115	409	COG0240	Glycerol-3-phosphate dehydrogenase	329
639003372	159	52.6	5	158	1	154	3.0e-44	170	COG1952	Preprotein translocase subunit SecB	157
639003373	141	35.64	42	141	9	109	9.0e-14	69.6	COG0607	Rhodanese-related sulfurtransferase	110
639003374	385	30.83	27	379	34	419	2.0e-55	210	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
639003375	435	50	28	362	27	364	4.0e-104	371	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
639003376	188	34.76	1	171	2	188	2.0e-21	95.6	COG0693	Putative intracellular protease/amidase	188
639003377	555	44.78	2	525	1	515	0.0e+00	487	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
639003378	212	30.5	8	204	1	200	4.0e-25	108	COG3165	Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain	204
639003379	257	51.05	19	254	1	235	2.0e-73	269	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
639003380	108	56.86	2	103	17	118	4.0e-33	132	COG3536	Uncharacterized conserved protein, DUF971 family	120
639003381	441	68.76	1	441	1	444	0.0e+00	673	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
639003382	180	68.57	3	177	1	175	1.0e-72	265	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
639003383	301	53.38	1	296	6	299	9.0e-90	323	COG4973	Site-specific recombinase XerC	299
639003384	229	35.51	9	222	4	215	1.0e-34	140	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
639003385	277	49.64	4	277	1	272	8.0e-92	330	COG0253	Diaminopimelate epimerase	272
639003386	425	50.77	11	394	7	393	3.0e-121	428	COG0019	Diaminopimelate decarboxylase	394
639003387	235	33.78	9	230	1	206	4.0e-38	151	COG0400	Predicted esterase	207
639003388	465	61.66	5	463	1	459	0.0e+00	626	COG0165	Argininosuccinate lyase	459
639003390	245	36.73	1	243	2	244	3.0e-42	165	COG3279	DNA-binding response regulator, LytR/AlgR family	244
639003393	309	57.43	3	304	1	303	5.0e-107	380	COG0181	Porphobilinogen deaminase	307
639003394	350	30.46	2	344	39	354	4.0e-27	115	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
639003395	420	31.42	1	400	1	399	4.0e-51	195	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
639003403	267	44.53	7	262	1	261	9.0e-79	286	COG0708	Exonuclease III	261
639003404	396	40.35	4	396	1	392	1.0e-82	300	COG0183	Acetyl-CoA acetyltransferase	392
639003405	586	59.9	11	414	3	407	0.0e+00	537	COG0538	Isocitrate dehydrogenase	407
639003406	880	47.32	3	880	2	910	0.0e+00	952	COG2352	Phosphoenolpyruvate carboxylase	910
639003407	215	37.26	3	211	1	201	3.0e-42	165	COG0461	Orotate phosphoribosyltransferase	201
639003409	578	42.21	1	573	1	568	4.0e-126	445	COG3263	NhaP-type Na+/H+ and K+/H+ antiporter with C-terminal TrkAC and CorC domains	574
639003410	305	53.31	26	295	1	263	1.0e-83	302	COG0548	Acetylglutamate kinase	265
639003411	841	36.17	387	833	5	460	1.0e-101	365	COG1109	Phosphomannomutase	464
639003413	151	45.03	1	151	1	148	2.0e-47	181	COG0756	dUTPase	148
639003414	408	49.37	4	397	2	391	4.0e-113	402	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
639003415	224	52.68	1	224	1	224	5.0e-77	280	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
639003417	292	36.18	4	290	51	333	2.0e-62	232	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
639003424	855	50.82	11	850	6	842	0.0e+00	944	COG0249	DNA mismatch repair ATPase MutS	843
639003425	164	51.55	4	164	2	161	1.0e-45	176	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
639003426	197	34.08	11	176	1	178	2.0e-28	119	COG1514	2'-5' RNA ligase	180
639003427	351	63.86	3	284	3	279	9.0e-88	317	COG0468	RecA/RadA recombinase	279
639003428	162	30.25	1	160	13	174	4.0e-24	104	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
639003429	869	55.09	1	868	2	879	0.0e+00	1130	COG0013	Alanyl-tRNA synthetase	879
639003430	420	46.24	1	405	1	447	1.0e-113	403	COG0527	Aspartokinase	447
639003431	69	63.08	1	65	1	65	6.0e-20	88.8	COG1551	sRNA-binding carbon storage regulator CsrA	73
639003434	243	36.36	7	243	5	234	6.0e-49	187	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
639003435	331	42.15	2	325	8	318	1.0e-78	287	COG0837	Glucokinase	320
639003436	340	56.25	3	337	1	296	6.0e-114	404	COG1023	6-phosphogluconate dehydrogenase (decarboxylating)	300
639003439	181	46.2	11	178	4	173	6.0e-43	167	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
639003441	137	42.34	1	136	3	137	4.0e-35	140	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
639003442	113	54.08	6	101	7	104	7.0e-33	132	COG4517	Uncharacterized protein	109
639003448	796	47.96	48	778	4	710	0.0e+00	711	COG2217	Cation transport ATPase	713
639003453	442	39.53	15	442	22	449	5.0e-86	311	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
639003460	350	25.88	10	328	12	336	3.0e-24	106	COG3240	Phospholipase/lecithinase/hemolysin	370
639003466	286	29.96	1	257	11	262	1.0e-31	130	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
639003467	689	44.84	9	686	8	665	0.0e+00	675	COG1331	Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains	667
639003469	291	23.89	49	288	48	279	4.0e-16	78.8	COG3725	Membrane protein required for beta-lactamase induction	282
639003470	187	28.92	25	186	31	195	7.0e-10	57.2	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
639003471	105	36.84	26	105	6	99	2.0e-13	67.3	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
639003472	93	38.3	1	93	1	94	4.0e-18	82.6	COG3549	Plasmid maintenance system killer protein	94
639003473	432	28.71	122	422	72	380	4.0e-30	125	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639003475	374	22.43	1	361	1	359	8.0e-13	68.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639003476	107	30.3	5	103	3	96	4.0e-09	53.1	COG3668	Plasmid stabilization system protein ParE	98
639003478	193	23.37	14	183	18	197	2.0e-14	72.2	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
639003479	237	23.74	19	210	8	264	3.0e-17	82.1	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
639003480	364	50.95	7	364	5	372	4.0e-128	451	COG0562	UDP-galactopyranose mutase	374
639003482	75	39.73	1	73	4	76	2.0e-15	73.9	COG4710	Predicted DNA-binding protein with an HTH domain	80
639003485	80	35.29	7	74	2	69	5.0e-08	49.6	COG4456	Virulence-associated protein VagC (function unknown)	74
639003486	137	38.81	6	137	3	133	3.0e-21	94.5	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
639003489	101	41.18	10	94	5	89	2.0e-18	83.8	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
639003495	433	28.01	22	424	7	413	2.0e-26	113	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
639003496	94	52.81	1	89	1	89	3.0e-20	90.1	COG5606	Predicted DNA-binding protein, XRE-type HTH domain	91
639003497	122	46.88	2	97	20	115	1.0e-22	98.4	COG4679	Phage-related protein	116
639003498	116	38.14	1	116	15	130	2.0e-16	78.2	COG4374	PIN domain nuclease, a component of toxin-antitoxin system (PIN domain)	130
639003501	65	35.19	1	53	1	54	9.0e-08	48.4	COG5428	Uncharacterized protein YuzE	69
639003508	147	25.35	5	142	5	143	4.0e-09	54.2	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
639003509	951	17.07	127	590	4	486	1.0e-08	55.9	COG0210	Superfamily I DNA or RNA helicase	655
639003513	111	31.53	1	111	1	109	6.0e-13	66.2	COG3784	Uncharacterized conserved protein YdbL, DUF1318 family	109
639003516	140	28.97	1	140	3	133	3.0e-12	64	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
639003523	127	26.88	31	123	25	116	9.0e-12	62.6	COG1334	Uncharacterized conserved protein, FlaG/YvyC family	120
639003524	682	36.72	1	391	3	393	5.0e-51	195	COG1345	Flagellar capping protein FliD	483
639003525	143	42.86	4	129	3	125	1.0e-27	115	COG1516	Flagellin-specific chaperone FliS	132
639003527	479	44.03	1	474	4	459	2.0e-106	380	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
639003528	106	35.92	4	106	7	105	2.0e-13	67.3	COG1677	Flagellar hook-basal body complex protein FliE	105
639003529	580	35.05	28	578	8	545	3.0e-103	369	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
639003530	274	43.08	1	259	3	262	3.0e-57	215	COG1536	Flagellar motor switch protein FliG	339
639003533	457	54.67	10	446	4	440	0.0e+00	581	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
639003534	148	29.17	1	144	1	144	2.0e-09	54.9	COG2882	Flagellar biosynthesis chaperone FliJ	148
639003536	173	20.81	1	173	5	159	8.0e-17	80.3	COG1580	Flagellar basal body-associated protein FliL	159
639003537	336	43.96	5	325	3	323	2.0e-92	332	COG1868	Flagellar motor switch protein FliM	332
639003538	138	36.22	2	127	10	136	1.0e-20	92.4	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
639003539	147	32.11	38	144	24	131	2.0e-16	78	COG3190	Flagellar biogenesis protein FliO	137
639003540	245	52.48	2	243	7	248	1.0e-69	256	COG1338	Flagellar biosynthetic protein FliP	248
639003541	89	47.19	1	89	1	89	1.0e-16	78.3	COG1987	Flagellar biosynthesis protein FliQ	89
639003542	258	39.84	1	256	1	254	2.0e-41	163	COG1684	Flagellar biosynthesis protein FliR	258
639003543	385	46.39	4	363	2	361	6.0e-111	394	COG1377	Flagellar biosynthesis protein FlhB	363
639003544	706	54.52	13	697	14	694	0.0e+00	847	COG1298	Flagellar biosynthesis pathway, component FlhA	696
639003545	439	32.46	2	423	1	406	2.0e-78	286	COG1419	Flagellar biosynthesis GTPase FlhF	407
639003546	290	36.09	18	279	2	259	8.0e-50	190	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
639003547	240	39.73	18	239	27	247	3.0e-52	198	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
639003553	388	24.82	17	292	18	277	8.0e-27	115	COG3016	Uncharacterized iron-regulated protein	295
639003555	185	40.33	3	181	2	176	1.0e-31	129	COG0431	NAD(P)H-dependent FMN reductase	184
639003556	476	48.79	22	476	4	432	0.0e+00	473	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
639003558	155	51.35	2	147	8	154	4.0e-44	170	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
639003559	137	29.41	2	117	1	117	8.0e-10	56.3	COG0517	CBS domain	117
639003561	531	27.95	37	489	22	485	3.0e-100	359	COG0069	Glutamate synthase domain 2	485
639003562	214	48.85	1	214	3	219	6.0e-55	207	COG1926	Predicted phosphoribosyltransferase	220
639003564	486	32.1	19	375	42	416	1.0e-52	201	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
639003565	252	27.78	1	207	23	237	1.0e-21	96.6	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
639003566	131	54.55	10	130	9	129	4.0e-41	160	COG1607	Acyl-CoA hydrolase	157
639003570	318	29.36	10	318	16	363	9.0e-31	127	COG4269	Uncharacterized membrane protein YjgN, DUF898 family	364
639003575	433	43.95	5	429	3	431	4.0e-97	348	COG0733	Na+-dependent transporter, SNF family	439
639003577	179	42.05	6	174	1	174	4.0e-30	124	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
639003578	194	33.83	3	193	2	188	4.0e-25	107	COG0693	Putative intracellular protease/amidase	188
639003579	322	25.33	1	299	15	313	3.0e-43	169	COG3965	Predicted Co/Zn/Cd cation transporter, cation efflux family	314
639003583	306	40.27	5	296	4	301	2.0e-56	212	COG1597	Diacylglycerol kinase family enzyme	301
639003588	573	37.79	23	573	1	533	0.0e+00	468	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
639003591	183	20.96	1	165	7	172	2.0e-09	55.7	COG3945	Hemerythrin-like domain	189
639003592	377	37.17	149	372	3	226	5.0e-27	115	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
639003595	392	32.98	43	389	63	435	8.0e-59	221	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
639003596	334	46.1	15	322	1	297	2.0e-78	285	COG1533	DNA repair photolyase	297
639003597	205	46.83	3	205	2	206	8.0e-52	196	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
639003598	215	54.88	1	215	7	221	3.0e-37	148	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
639003599	407	34.41	3	280	1	276	8.0e-39	155	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
639003600	158	42.07	1	145	7	150	9.0e-36	142	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
639003601	179	28.12	30	153	2	127	2.0e-13	68.8	COG0526	Thiol-disulfide isomerase or thioredoxin	127
639003602	662	56.54	1	639	1	641	0.0e+00	651	COG1138	Cytochrome c biogenesis factor	648
639003603	154	56.3	3	137	4	138	1.0e-43	168	COG2332	Cytochrome c-type biogenesis protein CcmE	153
639003604	51	38	2	51	5	54	1.0e-07	48	COG3114	Heme exporter protein D	67
639003605	216	47.52	2	202	71	272	2.0e-35	142	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
639003609	556	32.9	14	555	179	786	3.0e-81	296	COG2374	Predicted extracellular nuclease	798
639003610	737	46.11	14	733	5	700	0.0e+00	743	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
639003616	306	29.86	15	288	20	304	2.0e-41	162	COG0010	Arginase family enzyme	305
639003617	292	32.63	1	282	3	277	1.0e-47	183	COG0421	Spermidine synthase	282
639003619	1146	51.8	7	1142	6	1135	0.0e+00	1370	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
639003621	246	41.94	3	246	19	262	3.0e-61	228	COG0005	Purine nucleoside phosphorylase	262
639003622	191	35.09	19	188	8	177	4.0e-42	164	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
639003623	146	29.66	27	142	2	117	5.0e-12	63.7	COG2044	Predicted peroxiredoxin	120
639003624	337	40.59	1	335	9	339	2.0e-67	249	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
639003627	176	50.32	14	168	1	154	1.0e-44	172	COG2954	CYTH domain, found in class IV adenylate cyclase and various triphosphatases	156
639003628	220	35.21	6	212	6	217	2.0e-45	175	COG1878	Kynurenine formamidase	218
639003629	232	61.4	1	228	1	228	4.0e-91	327	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
639003630	243	27.43	4	237	5	228	5.0e-31	128	COG0300	Short-chain dehydrogenase	265
639003632	655	34.24	82	629	1	522	9.0e-115	407	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
639003633	162	56.05	1	157	1	156	4.0e-54	203	COG0315	Molybdenum cofactor biosynthesis enzyme	157
639003634	108	43.82	18	106	6	94	5.0e-25	106	COG2154	Pterin-4a-carbinolamine dehydratase	101
639003636	230	34.47	1	200	1	200	1.0e-37	149	COG0625	Glutathione S-transferase	211
639003637	436	45.52	28	429	1	357	7.0e-126	444	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
639003638	108	42.42	4	65	5	68	7.0e-09	52.5	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
639003639	163	37.88	3	124	2	133	1.0e-26	112	COG1959	DNA-binding transcriptional regulator, IscR family	150
639003645	137	32.84	2	128	19	151	2.0e-19	88.1	COG0782	Transcription elongation factor, GreA/GreB family	151
639003648	405	22.7	29	398	34	394	1.0e-16	81	COG2814	Predicted arabinose efflux permease, MFS family	394
639003649	362	59.43	1	347	1	339	0.0e+00	518	COG1088	dTDP-D-glucose 4,6-dehydratase	340
639003650	297	55.36	7	295	1	286	1.0e-114	406	COG1209	dTDP-glucose pyrophosphorylase	286
639003651	182	55.93	1	177	1	173	8.0e-60	222	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
639003652	291	50.35	1	285	1	281	1.0e-79	289	COG1091	dTDP-4-dehydrorhamnose reductase	281
639003654	665	21.55	10	665	6	608	2.0e-25	111	COG4206	Outer membrane cobalamin receptor protein	608
639003658	174	55.56	4	144	1	142	2.0e-46	178	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
639003659	107	27.52	1	106	1	109	3.0e-16	76.5	COG0607	Rhodanese-related sulfurtransferase	110
639003660	200	19.43	1	173	6	178	2.0e-11	62.7	COG3945	Hemerythrin-like domain	189
639003661	158	43.56	1	157	16	173	1.0e-36	145	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
639003662	242	27.5	19	206	2	198	3.0e-28	118	COG0300	Short-chain dehydrogenase	265
639003663	662	42.79	16	631	1	588	0.0e+00	608	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
639003665	310	41.64	23	302	1	264	1.0e-62	233	COG1526	Formate dehydrogenase assembly factor FdhD	266
639003666	329	54.66	1	320	1	322	7.0e-130	456	COG1087	UDP-glucose 4-epimerase	329
639003668	645	53.46	5	639	2	619	0.0e+00	742	COG0326	Molecular chaperone, HSP90 family	623
639003669	240	42.29	14	239	1	217	8.0e-45	173	COG0850	Septum formation inhibitor MinC	219
639003670	271	67.77	1	271	1	272	2.0e-114	405	COG2894	Septum formation inhibitor-activating ATPase MinD	272
639003671	95	44.44	1	90	1	86	2.0e-19	87.6	COG0851	Septum formation topological specificity factor MinE	88
639003672	539	28.81	431	533	1	115	5.0e-09	56.4	COG1388	LysM repeat	124
639003673	257	31.08	5	222	16	248	2.0e-18	86.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
639003675	147	61.81	1	141	1	144	1.0e-50	192	COG0328	Ribonuclease HI	154
639003676	245	37.82	1	236	13	242	4.0e-46	178	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
639003677	240	26.92	11	239	4	227	2.0e-23	103	COG1011	FMN phosphatase YigB, HAD superfamily	229
639003678	255	26.94	5	243	3	246	4.0e-44	171	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
639003679	785	31.05	64	602	1	475	2.0e-74	274	COG3119	Arylsulfatase A or related enzyme	475
639003684	359	49.06	30	347	18	324	6.0e-108	384	COG0379	Quinolinate synthase	324
639003685	469	33.86	43	469	1	438	8.0e-70	258	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
639003686	164	31.62	30	146	29	145	2.0e-16	78.8	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
639003688	260	54.73	3	244	6	246	5.0e-84	304	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
639003689	248	40.69	23	246	14	242	3.0e-56	212	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
639003690	367	22.67	9	330	39	297	6.0e-16	79	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
639003696	393	44.22	5	388	1	387	6.0e-108	384	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
639003699	280	31.75	7	273	13	283	4.0e-46	178	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
639003700	452	37.9	13	443	24	455	1.0e-109	390	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
639003701	426	28.27	6	422	6	415	3.0e-35	143	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
639003702	205	31.65	3	202	1	211	1.0e-23	103	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
639003703	97	31.18	1	92	1	89	2.0e-08	50.4	COG3668	Plasmid stabilization system protein ParE	98
639003704	90	40.54	1	74	3	72	3.0e-10	56.5	COG3905	Predicted transcriptional regulator	83
639003706	219	34.95	1	200	1	194	5.0e-58	217	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
639003709	480	33.84	10	461	1	442	7.0e-39	155	COG0531	Amino acid transporter	466
639003713	399	39.61	6	399	2	392	3.0e-80	292	COG0183	Acetyl-CoA acetyltransferase	392
639003714	788	28.83	472	736	1	251	5.0e-20	93.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
639003714	788	35.41	7	310	3	298	2.0e-62	233	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
639003715	830	28.3	153	512	37	382	1.0e-43	172	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
639003716	203	20.45	1	174	4	179	4.0e-06	45	COG1309	DNA-binding transcriptional regulator, AcrR family	201
639003717	155	41.13	1	138	1	141	3.0e-35	141	COG1959	DNA-binding transcriptional regulator, IscR family	150
639003718	166	31.3	17	145	13	139	3.0e-15	75	COG3151	Uncharacterized protein YqiB, DUF1249 family	147
639003719	273	41.37	3	273	2	273	9.0e-69	253	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
639003720	792	49.87	1	786	1	735	0.0e+00	740	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
639003721	369	28.41	25	369	11	352	5.0e-35	142	COG0628	Predicted PurR-regulated permease PerM	355
639003726	411	34.26	24	409	14	406	9.0e-42	164	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
639003732	406	26.41	22	404	2	379	3.0e-34	139	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
639003733	831	28.53	299	679	92	450	3.0e-41	164	COG5002	Signal transduction histidine kinase	459
639003736	363	41.18	58	356	2	295	5.0e-78	284	COG0167	Dihydroorotate dehydrogenase	310
639003739	393	35.51	11	255	45	289	2.0e-66	246	COG1398	Fatty-acid desaturase	289
639003740	51	57.14	1	49	2	50	2.0e-10	57.1	COG0267	Ribosomal protein L33	50
639003741	78	59.74	1	76	1	77	8.0e-20	88.4	COG0227	Ribosomal protein L28	77
639003742	145	35.92	3	144	13	144	2.0e-23	101	COG0071	Molecular chaperone IbpA, HSP20 family	146
639003743	314	36.76	1	308	1	355	1.0e-70	260	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
639003747	628	65.65	137	594	1	431	0.0e+00	740	COG0422	Thiamine biosynthesis protein ThiC	432
639003748	220	38.12	9	210	1	202	7.0e-49	186	COG2518	Protein-L-isoaspartate O-methyltransferase	209
639003749	442	32.12	30	436	45	454	1.0e-42	168	COG1538	Outer membrane protein TolC	457
639003750	436	48.46	3	420	1	419	5.0e-130	458	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
639003751	315	44.3	1	304	2	308	2.0e-74	272	COG1560	Lauroyl/myristoyl acyltransferase	308
639003752	478	51.9	3	475	5	467	0.0e+00	554	COG2870	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase	467
639003755	346	33.43	1	346	1	334	6.0e-55	207	COG0859	ADP-heptose:LPS heptosyltransferase	334
639003756	372	29.09	1	361	3	380	5.0e-35	142	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639003757	92	31.91	1	92	1	94	4.0e-17	79.5	COG3549	Plasmid maintenance system killer protein	94
639003758	98	54.22	1	83	2	83	5.0e-21	92.7	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
639003762	101	33.7	2	92	6	94	7.0e-07	45.4	COG3668	Plasmid stabilization system protein ParE	98
639003763	693	19.07	1	688	1	748	5.0e-29	123	COG4772	Outer membrane receptor for Fe3+-dicitrate	753
639003773	163	38.46	53	154	20	122	2.0e-18	85.5	COG3245	Cytochrome c5	126
639003774	293	55.48	3	285	5	281	4.0e-97	348	COG2607	Predicted ATPase, AAA+ superfamily	287
639003781	413	52.62	4	401	5	405	9.0e-125	440	COG3844	Kynureninase	407
639003783	303	44.44	6	291	3	305	9.0e-65	240	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
639003784	300	65.65	39	300	1	262	1.0e-100	359	COG3483	Tryptophan 2,3-dioxygenase (vermilion)	262
639003785	413	29.59	12	275	2	239	1.0e-32	134	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
639003787	148	44.97	1	148	4	151	8.0e-43	165	COG1513	Cyanate lyase	151
639003792	275	34.58	1	236	2	234	3.0e-38	151	COG0300	Short-chain dehydrogenase	265
639003795	164	22.7	1	134	1	123	8.0e-07	46.8	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
639003796	152	31.29	1	140	4	150	8.0e-09	53.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
639003801	1161	22.81	282	743	34	421	8.0e-23	103	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
639003804	374	39.77	53	315	1	260	8.0e-66	244	COG1180	Pyruvate-formate lyase-activating enzyme	260
639003805	264	29.89	4	262	2	279	8.0e-45	173	COG1355	Predicted class III extradiol dioxygenase, MEMO1 family	279
639003806	200	32.64	2	187	4	191	3.0e-27	114	COG2078	Uncharacterized conserved protein, AMMECR1 domain	203
639003807	1061	39.81	25	443	1	391	3.0e-93	337	COG0506	Proline dehydrogenase	391
639003807	1061	54.35	443	1061	1	608	0.0e+00	797	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
639003808	477	49.21	18	460	1	437	0.0e+00	468	COG1570	Exonuclease VII, large subunit	440
639003809	227	33.18	1	219	64	282	1.0e-36	146	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
639003810	1535	28.94	943	1440	1	499	4.0e-12	68.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
639003812	456	20	39	388	23	287	2.0e-06	47.6	COG1566	Multidrug resistance efflux pump	352
639003813	743	50.78	3	710	1	708	0.0e+00	768	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
639003814	488	30.49	255	477	1	170	9.0e-33	134	COG0516	IMP dehydrogenase/GMP reductase	170
639003814	488	39.29	94	199	7	116	3.0e-13	70.6	COG0517	CBS domain	117
639003815	525	42.23	8	206	2	198	4.0e-55	209	COG0518	GMP synthase - Glutamine amidotransferase domain	198
639003815	525	65.41	208	525	2	315	0.0e+00	515	COG0519	GMP synthase, PP-ATPase domain/subunit	315
639003816	181	53.38	22	168	4	151	7.0e-45	173	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
639003817	590	26.32	245	543	8	307	6.0e-27	116	COG0668	Small-conductance mechanosensitive channel	316
639003820	191	28.57	8	188	12	191	4.0e-30	124	COG3963	Phospholipid N-methyltransferase	194
639003826	188	40.85	45	185	1	141	3.0e-27	114	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
639003828	256	31.38	15	252	75	307	5.0e-22	98.1	COG0679	Predicted permease	311
639003831	681	34.25	4	675	5	692	0.0e+00	532	COG0480	Translation elongation factor EF-G, a GTPase	697
639003832	463	30.02	41	463	32	456	1.0e-42	168	COG0471	Di- and tricarboxylate transporter	461
639003837	715	37.93	9	296	59	336	1.0e-41	165	COG0642	Signal transduction histidine kinase	336
639003838	549	52.32	140	548	4	411	0.0e+00	475	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
639003846	195	39.44	16	195	36	214	7.0e-43	166	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
639003847	257	21.72	35	254	15	229	3.0e-15	75.8	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
639003848	228	35.47	2	203	10	212	1.0e-29	123	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
639003851	906	58.23	4	905	1	861	0.0e+00	1124	COG1048	Aconitase A	861
639003857	165	29.29	18	154	8	136	7.0e-10	56.9	COG3415	Transposase	138
639003858	133	37.5	24	127	19	122	2.0e-19	88.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
639003861	138	22.5	2	121	3	117	8.0e-10	56.4	COG2210	Peroxiredoxin family protein	137
639003865	357	25.48	8	357	41	459	2.0e-36	146	COG0277	FAD/FMN-containing dehydrogenase	459
639003866	412	28.35	16	402	2	382	3.0e-57	215	COG0247	Fe-S oxidoreductase	388
639003867	274	37.45	7	272	10	281	8.0e-65	240	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
639003871	707	52.93	13	696	15	689	0.0e+00	794	COG1523	Pullulanase/glycogen debranching enzyme	697
639003872	313	56.67	16	313	1	300	1.0e-101	363	COG4974	Site-specific recombinase XerD	300
639003873	256	39.5	1	231	2	238	2.0e-36	146	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
639003874	275	31.28	57	274	6	228	1.0e-25	110	COG1018	Ferredoxin-NADP reductase	266
639003875	256	35.51	4	235	6	247	2.0e-36	146	COG0584	Glycerophosphoryl diester phosphodiesterase	257
639003876	657	34.61	61	461	9	420	6.0e-47	182	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
639003878	360	40.06	5	360	3	354	3.0e-77	282	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
639003881	65	34.38	1	64	3	66	1.0e-07	48.4	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
639003882	482	52.02	86	481	4	390	3.0e-126	445	COG0372	Citrate synthase	390
639003884	334	68.5	1	327	1	324	0.0e+00	518	COG0435	Glutathionyl-hydroquinone reductase	324
639003891	912	41.34	1	887	14	909	0.0e+00	778	COG0474	Magnesium-transporting ATPase (P-type)	917
639003896	520	31.81	4	517	3	477	4.0e-69	255	COG0297	Glycogen synthase	487
639003897	544	35.78	3	530	5	524	0.0e+00	520	COG0033	Phosphoglucomutase	524
639003898	421	54.32	11	413	1	386	0.0e+00	502	COG0448	ADP-glucose pyrophosphorylase	393
639003899	827	46.29	6	807	9	750	0.0e+00	787	COG0058	Glucan phosphorylase	750
639003903	152	60.14	4	146	2	140	1.0e-56	212	COG0229	Peptide methionine sulfoxide reductase MsrB	140
639003904	171	47.67	2	167	3	174	5.0e-64	237	COG0225	Peptide methionine sulfoxide reductase MsrA	174
639003905	260	33.7	167	256	3	94	1.0e-12	66.9	COG2388	Predicted acetyltransferase, GNAT superfamily	99
639003907	247	41.7	10	243	2	236	7.0e-71	260	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
639003908	510	37.97	12	292	6	300	2.0e-68	253	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
639003908	510	56.28	305	503	20	218	3.0e-54	206	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
639003909	215	29.47	11	215	10	215	3.0e-27	115	COG2345	Predicted transcriptional regulator, ArsR family	218
639003911	472	33.04	13	460	24	457	1.0e-55	211	COG1538	Outer membrane protein TolC	457
639003912	371	33.64	2	321	18	338	2.0e-67	249	COG1566	Multidrug resistance efflux pump	352
639003916	765	19.11	68	765	1	768	4.0e-32	133	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
639003918	710	25.93	11	710	21	719	3.0e-70	260	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
639003921	376	29.17	1	318	19	346	7.0e-35	141	COG1373	Predicted ATPase, AAA+ superfamily	398
639003924	180	23.87	34	175	9	157	5.0e-15	74.1	COG1225	Peroxiredoxin	157
639003932	128	46.46	2	128	3	129	2.0e-30	124	COG3744	PIN domain nuclease, a component of toxin-antitoxin system (PIN domain)	130
639003933	75	41.33	1	71	1	75	4.0e-10	56.2	COG4118	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor	84
639003935	574	39.11	5	564	13	565	6.0e-126	444	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
639003936	569	30.91	31	452	3	399	3.0e-92	333	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
639003937	112	32.46	1	112	2	115	1.0e-27	114	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
639003947	531	25.93	91	514	5	396	3.0e-43	169	COG1061	Superfamily II DNA or RNA helicase	442
639003953	397	46.27	6	386	2	378	4.0e-104	371	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
639003957	305	43.71	10	293	24	308	2.0e-64	239	COG1560	Lauroyl/myristoyl acyltransferase	308
639003958	84	36.36	15	69	10	62	3.0e-09	53.5	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
639003959	305	43.49	5	293	1	283	9.0e-72	263	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
639003960	971	48.24	43	968	43	958	0.0e+00	886	COG1391	Glutamine synthetase adenylyltransferase	963
639003963	201	38.79	7	201	4	217	2.0e-45	175	COG1458	Predicted DNA-binding protein containing PIN domain, UPF0278 family	221
639003964	378	32.86	31	374	36	379	3.0e-64	238	COG1423	ATP-dependent RNA circularization protein, DNA/RNA ligase (PAB1020)  family	382
639003965	471	19.7	1	465	1	433	3.0e-20	93.6	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
639003967	361	33.85	120	354	29	281	8.0e-32	131	COG1408	Predicted phosphohydrolase, MPP superfamily	284
639003969	595	53.67	144	592	7	445	0.0e+00	543	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
639003970	173	63.92	16	173	3	158	5.0e-57	213	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
639003971	381	48.49	8	371	1	363	2.0e-117	416	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
639003972	234	31.1	30	214	6	214	9.0e-19	87.3	COG2755	Lysophospholipase L1 or related esterase	216
639003973	221	62.32	15	219	20	226	2.0e-68	252	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
639003974	827	36.55	2	826	6	829	0.0e+00	539	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
639003975	279	50	14	263	8	265	7.0e-77	280	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
639003977	221	36.52	3	217	1	230	1.0e-44	172	COG2063	Flagellar basal body L-ring protein FlgH	230
639003978	371	54.72	1	371	1	365	7.0e-117	413	COG1706	Flagellar basal body P-ring protein FlgI	365
639003979	315	37.28	130	296	20	181	1.0e-33	137	COG1705	Flagellum-specific peptidoglycan hydrolase FlgJ	201
639003980	652	31.25	1	443	3	443	3.0e-62	233	COG1256	Flagellar hook-associated protein FlgK	552
639003981	400	24.25	1	400	1	357	1.0e-34	141	COG1344	Flagellin and related hook-associated protein FlgL	360
639003985	225	31.34	3	219	6	212	6.0e-22	97.9	COG0705	Membrane associated serine protease, rhomboid family	228
639003986	144	41.3	6	135	8	142	2.0e-22	98.6	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
639003987	604	49.58	17	604	1	587	0.0e+00	613	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
639003988	570	43.38	14	563	9	510	0.0e+00	506	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
639003989	596	17.97	136	596	70	458	4.0e-27	116	COG0471	Di- and tricarboxylate transporter	461
639003991	479	22.27	13	465	7	403	7.0e-23	102	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
639003994	387	46.55	6	387	1	391	2.0e-94	339	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
639003995	535	46.08	12	535	1	526	0.0e+00	630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
639003996	261	40.23	1	259	2	257	2.0e-43	169	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
639003997	665	54.07	1	663	1	644	0.0e+00	779	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
639003999	354	34.02	43	323	38	326	8.0e-50	191	COG3608	Predicted deacylase	331
639004000	177	49.13	1	173	3	168	1.0e-54	205	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
639004001	448	37.8	1	447	1	453	3.0e-111	395	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
639004002	699	52.25	13	699	1	683	0.0e+00	833	COG0339	Zn-dependent oligopeptidase	683
639004003	256	47.13	1	255	1	261	3.0e-84	304	COG0708	Exonuclease III	261
639004009	320	30.59	18	308	20	286	5.0e-38	151	COG4974	Site-specific recombinase XerD	300
639004010	311	47.64	4	299	1	295	1.0e-89	323	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
639004011	209	50.3	34	198	1	158	1.0e-48	186	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
639004013	211	51.27	19	209	16	211	5.0e-51	194	COG3571	Predicted hydrolase of the alpha/beta-hydrolase fold	213
639004014	261	28.7	141	254	18	132	3.0e-15	75.9	COG3187	Heat shock protein HslJ	142
639004015	102	23.81	20	82	1	63	5.0e-07	46.1	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
639004016	254	48.21	31	254	1	224	4.0e-58	218	COG4149	ABC-type molybdate transport system, permease component	225
639004017	353	45.74	3	352	2	350	6.0e-93	334	COG4148	ABC-type molybdate transport system, ATPase component	352
639004019	269	39.39	132	197	4	69	2.0e-11	63	COG3585	Molybdopterin-binding protein	69
639004019	269	47.01	21	137	14	130	7.0e-22	97.7	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
639004020	272	50.37	1	271	1	272	6.0e-89	320	COG0266	Formamidopyrimidine-DNA glycosylase	273
639004021	331	35.52	2	328	69	403	2.0e-63	236	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
639004023	586	40.95	1	476	21	506	2.0e-120	426	COG0513	Superfamily II DNA and RNA helicase	513
639004024	146	33.59	22	143	25	154	2.0e-14	71.5	COG2153	Predicted N-acyltransferase, GNAT family	155
639004025	455	33.04	12	455	1	435	2.0e-95	342	COG0015	Adenylosuccinate lyase	438
639004026	462	56.09	6	459	3	462	0.0e+00	641	COG0114	Fumarate hydratase class II	462
639004027	272	24.38	31	230	3	179	4.0e-09	55.7	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
639004028	212	44.29	2	210	1	210	8.0e-50	190	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
639004029	224	24.67	1	220	2	200	6.0e-22	97.8	COG1573	Uracil-DNA glycosylase	202
639004030	606	51.25	5	604	1	581	0.0e+00	633	COG0322	Excinuclease UvrABC, nuclease subunit	581
639004031	211	46.37	1	179	10	185	1.0e-27	116	COG0558	Phosphatidylglycerophosphate synthase	192
639004040	518	33.83	275	471	62	259	2.0e-30	127	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
639004041	371	46.07	1	367	3	368	3.0e-93	335	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
639004042	117	55.05	9	117	2	110	3.0e-38	150	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
639004043	342	52.87	1	342	2	349	2.0e-119	422	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
639004044	604	33.04	27	473	15	442	4.0e-61	229	COG0038	H+/Cl- antiporter ClcA	443
639004045	141	55.17	1	141	6	149	5.0e-40	156	COG1981	Uncharacterized membrane protein	149
639004047	376	28.23	23	268	19	254	7.0e-30	125	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
639004053	372	34.04	55	368	85	390	7.0e-42	165	COG2385	Peptidoglycan hydrolase (amidase) enhancer domain	397
639004054	114	32	13	110	1	98	2.0e-10	57.5	COG2963	Transposase and inactivated derivatives	116
639004055	306	33.89	62	300	12	232	7.0e-24	104	COG2801	Transposase InsO and inactivated derivatives	232
639004059	427	41.75	27	419	5	400	9.0e-111	393	COG0162	Tyrosyl-tRNA synthetase	401
639004062	242	62.03	6	241	2	238	2.0e-94	338	COG0528	Uridylate kinase	238
