gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
643919759	386	40.73	1	381	5	369	5.0e-107	381	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
643919760	226	33.04	3	224	2	228	4.0e-49	187	COG1083	CMP-N-acetylneuraminic acid synthetase	228
643919761	471	35.49	1	470	1	471	6.0e-77	281	COG3400	Uncharacterized protein	471
643919762	377	54.59	3	372	1	359	0.0e+00	479	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
643919763	222	28.91	1	127	2	128	2.0e-14	72.7	COG2703	Hemerythrin	144
643919765	587	23.44	116	587	87	554	7.0e-52	199	COG2831	Hemolysin activation/secretion protein	554
643919768	692	31.65	10	692	12	699	1.0e-123	437	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
643919775	361	38.26	128	357	31	228	7.0e-49	187	COG0860	N-acetylmuramoyl-L-alanine amidase	231
643919776	365	31.69	7	364	3	330	6.0e-61	228	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
643919777	404	42.96	11	404	7	401	1.0e-103	370	COG0162	Tyrosyl-tRNA synthetase	401
643919781	237	56.09	1	229	4	232	3.0e-77	281	COG0528	Uridylate kinase	238
643919783	478	36.16	229	478	21	280	7.0e-46	178	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
643919784	259	58.69	1	259	4	261	6.0e-96	343	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
643919786	137	34.53	1	135	1	138	9.0e-27	112	COG3787	Uncharacterized conserved protein YhbP, UPF0306 family	145
643919789	200	41.38	3	200	1	201	2.0e-41	162	COG0237	Dephospho-CoA kinase	201
643919790	267	24.64	1	261	4	280	6.0e-27	114	COG0421	Spermidine synthase	282
643919791	149	27.97	1	143	1	131	2.0e-12	65.1	COG3187	Heat shock protein HslJ	142
643919793	434	22.25	8	431	8	411	3.0e-35	143	COG2195	Di- or tripeptidase	414
643919794	213	36.89	5	209	4	193	1.0e-42	166	COG2231	Uncharacterized protein related to Endonuclease III	215
643919796	374	30.16	4	366	1	343	1.0e-44	173	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
643919799	345	64.24	1	284	1	279	2.0e-84	306	COG0468	RecA/RadA recombinase	279
643919800	424	62.35	1	424	1	422	0.0e+00	609	COG0148	Enolase	423
643919803	166	34.73	5	164	4	167	3.0e-33	134	COG0703	Shikimate kinase	172
643919804	338	30.26	1	338	2	331	2.0e-45	176	COG0859	ADP-heptose:LPS heptosyltransferase	334
643919805	286	38.41	3	277	2	272	8.0e-74	270	COG2107	Predicted periplasmic solute-binding protein	272
643919806	271	18.66	4	270	3	241	1.0e-11	63.6	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
643919812	222	35.84	4	218	2	226	6.0e-43	167	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643919814	427	34.3	1	423	1	444	5.0e-87	315	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
643919815	240	61.57	1	240	2	243	2.0e-97	349	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
643919816	135	38.14	1	113	1	117	8.0e-19	86.1	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
643919817	586	38.6	6	455	5	454	1.0e-95	343	COG2812	DNA polymerase III, gamma/tau subunits	515
643919820	589	28.12	12	583	23	594	1.0e-78	287	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
643919821	105	35.48	13	105	13	105	3.0e-15	73.8	COG1677	Flagellar hook-basal body complex protein FliE	105
643919822	166	38.18	1	165	2	137	2.0e-38	151	COG1558	Flagellar basal body rod protein FlgC	137
643919823	144	41.18	5	140	3	132	2.0e-23	101	COG1815	Flagellar basal body rod protein FlgB	133
643919824	263	57.89	1	262	1	265	9.0e-84	303	COG4786	Flagellar basal body rod protein FlgG	265
643919825	277	35	1	274	1	265	6.0e-51	194	COG4786	Flagellar basal body rod protein FlgG	265
643919829	607	44.13	1	525	3	557	0.0e+00	591	COG0143	Methionyl-tRNA synthetase	558
643919831	286	36.89	3	286	16	321	2.0e-65	242	COG0158	Fructose-1,6-bisphosphatase	326
643919832	211	51.89	1	211	4	214	3.0e-75	274	COG0036	Pentose-5-phosphate-3-epimerase	220
643919833	270	52.38	1	270	1	268	3.0e-87	315	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
643919834	216	57.87	1	216	6	221	1.0e-66	245	COG2011	ABC-type methionine transport system, permease component	222
643919835	319	43.03	4	319	2	338	2.0e-97	349	COG1135	ABC-type methionine transport system, ATPase component	339
643919836	200	18.52	1	182	5	188	1.0e-14	73.4	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
643919840	180	42.78	2	180	18	191	5.0e-31	127	COG0576	Molecular chaperone GrpE (heat shock protein)	193
643919841	625	61.79	1	601	4	579	0.0e+00	650	COG0443	Molecular chaperone DnaK (HSP70)	579
643919842	412	18.52	26	412	54	450	8.0e-25	108	COG1538	Outer membrane protein TolC	457
643919844	1017	34.34	1	1008	2	1009	0.0e+00	781	COG0841	Multidrug efflux pump subunit AcrB	1009
643919846	618	40.96	3	610	33	652	0.0e+00	726	COG1166	Arginine decarboxylase (spermidine biosynthesis)	652
643919847	233	51.3	5	193	1	193	1.0e-61	229	COG1045	Serine acetyltransferase	194
643919849	474	58.07	2	473	14	489	0.0e+00	685	COG0753	Catalase	496
643919850	194	37.4	1	129	1	131	1.0e-21	96.6	COG2703	Hemerythrin	144
643919851	639	53.32	6	639	2	662	0.0e+00	843	COG0021	Transketolase	663
643919859	344	47.4	185	338	8	160	1.0e-46	180	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
643919860	290	58.19	18	249	39	270	5.0e-89	321	COG2326	Polyphosphate kinase 2, PPK2 family	270
643919863	464	25.45	321	428	9	116	8.0e-09	55.3	COG1406	Chemotaxis protein CheX, a CheY~P-specific phosphatase	153
643919864	133	32.61	1	133	1	138	9.0e-23	99.1	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
643919865	253	33.46	8	249	87	345	3.0e-48	185	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
643919867	367	28.05	122	365	8	244	1.0e-39	157	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
643919868	78	42.68	1	78	1	82	8.0e-14	68.7	COG0851	Septum formation topological specificity factor MinE	88
643919869	242	58.78	1	242	24	268	4.0e-95	341	COG2894	Septum formation inhibitor-activating ATPase MinD	272
643919870	204	37.84	17	195	2	185	1.0e-43	169	COG0164	Ribonuclease HII	199
643919871	805	47.5	11	805	8	776	0.0e+00	904	COG0466	ATP-dependent Lon protease, bacterial type	782
643919874	145	37.5	1	136	16	143	4.0e-23	100	COG1699	Flagellar assembly factor FliW	146
643919875	246	30.35	1	242	1	256	5.0e-46	177	COG0345	Pyrroline-5-carboxylate reductase	266
643919876	298	36.49	1	283	3	286	2.0e-67	249	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
643919877	451	42.13	66	445	14	395	4.0e-79	288	COG1921	Seryl-tRNA(Sec) selenium transferase	395
643919878	605	32.52	5	438	1	439	3.0e-80	293	COG3276	Selenocysteine-specific translation elongation factor	447
643919880	408	33.33	1	398	4	404	1.0e-83	303	COG0303	Molybdopterin biosynthesis enzyme	404
643919881	227	39.21	2	227	13	234	9.0e-52	197	COG0284	Orotidine-5'-phosphate decarboxylase	240
643919882	184	37.86	1	133	7	146	4.0e-27	114	COG0781	Transcription termination factor NusB	151
643919883	156	56.21	1	153	1	152	9.0e-50	189	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
643919884	268	55.81	1	266	18	273	9.0e-101	359	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
643919885	211	32.39	3	211	1	207	2.0e-46	179	COG0288	Carbonic anhydrase	207
643919886	256	30.12	1	239	1	241	5.0e-32	131	COG1360	Flagellar motor protein MotB	244
643919887	197	37.23	13	197	13	200	9.0e-30	123	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
643919889	404	33.99	3	403	1	401	3.0e-92	332	COG1252	NADH dehydrogenase, FAD-containing subunit	405
643919890	273	31.25	1	272	2	286	7.0e-50	190	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
643919891	88	54.02	1	87	2	88	4.0e-14	69.8	COG1987	Flagellar biosynthesis protein FliQ	89
643919892	273	62.35	1	255	2	255	4.0e-107	381	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
643919893	234	35.66	2	231	4	245	5.0e-60	224	COG0149	Triosephosphate isomerase	251
643919896	187	41.8	3	186	2	183	2.0e-58	218	COG0717	Deoxycytidine triphosphate deaminase	183
643919897	157	37.75	6	156	1	140	2.0e-23	101	COG0511	Biotin carboxyl carrier protein	140
643919898	455	58.52	6	449	1	446	0.0e+00	589	COG0439	Biotin carboxylase	449
643919901	396	42.39	1	396	4	399	1.0e-114	406	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
643919902	883	33.26	1	883	1	910	0.0e+00	621	COG2352	Phosphoenolpyruvate carboxylase	910
643919903	304	26.23	54	174	4	123	4.0e-09	55.8	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
643919905	125	22.47	20	108	3	90	2.0e-07	48	COG1359	Quinol monooxygenase YgiN	100
643919906	397	38.94	68	383	7	316	1.0e-79	290	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
643919907	159	26.52	15	144	1	131	6.0e-14	70.2	COG1917	Cupin domain protein related to quercetin dioxygenase	131
643919908	409	18.7	11	393	8	384	2.0e-14	73.7	COG2814	Predicted arabinose efflux permease, MFS family	394
643919909	450	25.74	51	435	13	411	4.0e-30	126	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
643919910	256	36.72	1	256	1	255	3.0e-32	132	COG1684	Flagellar biosynthesis protein FliR	258
643919911	213	41.94	2	206	1	217	3.0e-54	204	COG1136	ABC-type lipoprotein export system, ATPase component	226
643919912	355	44.94	1	355	1	295	4.0e-81	295	COG0264	Translation elongation factor EF-Ts	296
643919913	266	61.35	1	251	3	252	2.0e-94	338	COG0052	Ribosomal protein S2	252
643919914	288	21.43	2	285	35	296	2.0e-22	100	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
643919915	377	27.6	2	374	7	387	9.0e-52	197	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643919917	281	43.86	1	281	1	282	2.0e-92	332	COG0414	Panthothenate synthetase	285
643919919	167	50	1	160	1	162	4.0e-47	180	COG3516	Predicted component of the type VI protein secretion system	169
643919920	494	56.88	1	491	1	492	0.0e+00	723	COG3517	Predicted component of the type VI protein secretion system	495
643919921	164	24.68	1	151	1	153	3.0e-18	84.6	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
643919923	604	24.4	1	601	1	613	6.0e-67	249	COG3519	Type VI protein secretion system component VasA	621
643919926	876	38.59	12	872	1	784	0.0e+00	719	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
643919932	452	24.09	1	422	1	420	3.0e-40	160	COG3522	Predicted component of the type VI protein secretion system	446
643919935	348	32.2	5	345	16	361	1.0e-56	213	COG0687	Spermidine/putrescine-binding periplasmic protein	363
643919940	370	45.74	160	344	1	181	2.0e-34	139	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
643919944	386	48.91	5	325	4	319	8.0e-84	304	COG0206	Cell division GTPase FtsZ	338
643919945	596	48.01	1	596	1	597	0.0e+00	689	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
643919946	314	34.52	8	310	2	294	1.0e-66	246	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
643919947	405	36.49	11	378	4	361	2.0e-86	313	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
643919948	132	42.86	35	103	12	81	5.0e-18	83.5	COG1144	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit	91
643919949	186	27.84	1	186	3	193	2.0e-25	109	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
643919950	215	32.88	1	213	2	218	3.0e-32	131	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
643919952	403	25.83	11	381	23	394	7.0e-73	267	COG0019	Diaminopimelate decarboxylase	394
643919953	370	30.85	6	364	9	367	3.0e-38	152	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643919954	1041	46.12	1	1029	1	1009	0.0e+00	977	COG0841	Multidrug efflux pump subunit AcrB	1009
643919955	466	37.42	13	458	2	447	3.0e-74	272	COG1538	Outer membrane protein TolC	457
643919957	117	62.39	1	117	1	117	3.0e-39	153	COG0292	Ribosomal protein L20	118
643919958	64	47.62	1	62	1	63	3.0e-06	43.7	COG0291	Ribosomal protein L35	65
643919959	171	52.63	1	171	4	174	2.0e-53	201	COG0290	Translation initiation factor IF-3	176
643919960	605	50.09	34	605	22	585	0.0e+00	689	COG0441	Threonyl-tRNA synthetase	589
643919961	930	30.8	665	893	36	281	4.0e-35	143	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
643919963	321	35.4	2	318	1	318	2.0e-80	292	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
643919965	335	47.92	3	333	1	330	3.0e-102	365	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
643919966	235	39.04	14	234	7	233	5.0e-27	114	COG0670	Integral membrane protein, interacts with FtsH	233
643919968	298	28.15	7	137	4	138	1.0e-05	44.4	COG2510	Uncharacterized membrane protein	140
643919969	473	42.86	14	462	5	440	5.0e-124	438	COG1160	Predicted GTPases	444
643919970	1001	26.62	3	960	7	925	6.0e-112	399	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
643919973	596	38.31	154	594	67	488	2.0e-74	273	COG0286	Type I restriction-modification system, DNA methylase subunit	489
643919977	148	31.08	9	148	13	160	4.0e-20	90.7	COG0597	Lipoprotein signal peptidase	167
643919978	445	43.29	1	444	7	461	1.0e-112	400	COG1109	Phosphomannomutase	464
643919979	91	41.38	1	87	1	87	5.0e-09	52.6	COG0268	Ribosomal protein S20	88
643919980	356	61.39	1	356	4	363	0.0e+00	512	COG0216	Protein chain release factor A	363
643919982	143	42.07	1	143	2	138	7.0e-36	143	COG1832	Predicted CoA-binding protein	140
643919983	402	51.17	1	339	6	347	1.0e-109	389	COG1171	Threonine dehydratase	347
643919987	659	46.39	105	657	3	555	0.0e+00	586	COG0595	mRNA degradation ribonuclease J1/J2	555
643919988	246	44.53	1	244	7	250	2.0e-50	192	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
643919989	896	35.07	4	283	11	297	9.0e-53	202	COG0258	5'-3' exonuclease	310
643919989	896	42.07	314	896	6	593	0.0e+00	512	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
643919991	517	45.56	3	513	5	532	0.0e+00	567	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
643919992	341	61.77	7	333	10	336	3.0e-122	431	COG4239	ABC-type microcin C transport system, permease component YejE	341
643919993	345	63.81	1	344	1	362	0.0e+00	478	COG4174	ABC-type microcin C transport system, permease component YejB	364
643919994	603	30.77	4	590	12	560	5.0e-81	295	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
643919996	372	44.06	1	372	1	370	1.0e-105	376	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
643919997	190	34.36	5	190	4	198	5.0e-48	184	COG0353	Recombinational DNA repair protein RecR	198
643920001	609	27.47	3	609	2	552	3.0e-76	279	COG1256	Flagellar hook-associated protein FlgK	552
643920005	409	34.22	145	357	55	276	9.0e-34	137	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
643920008	375	31.22	4	371	2	380	2.0e-69	256	COG0763	Lipid A disaccharide synthetase	381
643920009	159	51.97	4	155	1	151	2.0e-40	158	COG0782	Transcription elongation factor, GreA/GreB family	151
643920010	144	64.34	3	144	6	148	1.0e-49	188	COG0756	dUTPase	148
643920013	212	25.1	1	201	2	248	9.0e-24	103	COG1521	Pantothenate kinase type III	251
643920015	421	47.16	1	421	1	421	0.0e+00	560	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
643920017	103	59.8	1	102	3	104	1.0e-32	131	COG0051	Ribosomal protein S10	104
643920018	192	38.65	1	189	2	207	6.0e-44	170	COG0087	Ribosomal protein L3	218
643920019	204	37.86	1	200	1	206	7.0e-44	170	COG0088	Ribosomal protein L4	214
643920020	93	38.82	7	89	5	89	3.0e-14	70.2	COG0089	Ribosomal protein L23	94
643920021	275	57.97	1	275	1	275	2.0e-102	365	COG0090	Ribosomal protein L2	275
643920022	93	68.89	1	90	1	90	1.0e-33	134	COG0185	Ribosomal protein S19	93
643920023	109	52.25	1	107	10	120	2.0e-28	117	COG0091	Ribosomal protein L22	120
643920024	235	57.78	12	235	1	225	2.0e-73	269	COG0092	Ribosomal protein S3	233
643920025	141	57.45	1	139	2	142	5.0e-43	166	COG0197	Ribosomal protein L16/L10AE	146
643920027	88	41.38	1	87	1	87	1.0e-15	74.5	COG0186	Ribosomal protein S17	87
643920028	122	75.41	1	122	1	122	1.0e-48	184	COG0093	Ribosomal protein L14	122
643920030	184	56.11	1	180	1	180	5.0e-63	233	COG0094	Ribosomal protein L5	180
643920031	61	45.9	1	61	1	61	1.0e-15	74.5	COG0199	Ribosomal protein S14	61
643920032	131	43.51	1	131	2	132	2.0e-38	151	COG0096	Ribosomal protein S8	132
643920033	178	51.67	1	177	1	178	3.0e-52	198	COG0097	Ribosomal protein L6P/L9E	178
643920034	118	42.28	4	118	3	125	1.0e-24	105	COG0256	Ribosomal protein L18	125
643920035	146	64.14	2	145	18	162	4.0e-49	186	COG0098	Ribosomal protein S5	181
643920036	133	44.53	1	123	1	128	1.0e-20	92.3	COG0200	Ribosomal protein L15	152
643920037	419	46.46	1	414	15	430	3.0e-99	355	COG0201	Preprotein translocase subunit SecY	436
643920038	252	45.67	1	251	1	251	9.0e-80	290	COG0024	Methionine aminopeptidase	255
643920039	72	63.89	1	72	1	72	1.0e-24	104	COG0361	Translation initiation factor IF-1	75
643920041	122	59.32	1	118	1	118	1.0e-39	155	COG0099	Ribosomal protein S13	121
643920042	130	64.62	1	130	1	129	6.0e-43	166	COG0100	Ribosomal protein S11	129
643920043	208	58.57	1	208	1	205	2.0e-57	215	COG0522	Ribosomal protein S4 or related protein	205
643920044	329	36.83	10	322	3	315	5.0e-64	238	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
643920045	116	60.34	1	116	1	116	6.0e-39	152	COG0203	Ribosomal protein L17	116
643920046	167	34.73	1	160	5	171	3.0e-29	121	COG0723	Rieske Fe-S protein	177
643920047	409	42.46	4	393	1	369	1.0e-79	290	COG1290	Cytochrome b subunit of the bc complex	381
643920048	280	23.57	20	280	1	250	8.0e-29	120	COG2857	Cytochrome c1	250
643920049	770	39.77	5	767	1	750	0.0e+00	698	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
643920050	205	28.72	4	190	7	193	3.0e-29	121	COG0352	Thiamine monophosphate synthase	211
643920051	98	25.56	4	88	3	92	7.0e-11	58.8	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
643920053	147	34.15	1	82	1	82	2.0e-11	61.5	COG1826	Sec-independent protein translocase protein TatA	94
643920054	244	45.27	3	243	8	250	5.0e-50	191	COG0805	Sec-independent protein secretion pathway component TatC	255
643920055	346	44.63	4	346	1	343	3.0e-104	371	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
643920056	190	32.96	1	176	12	187	2.0e-26	112	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
643920059	216	18.31	4	204	2	214	5.0e-17	81.4	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643920061	126	43.12	1	107	2	110	5.0e-26	110	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
643920062	331	48.38	1	329	10	335	4.0e-107	381	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
643920063	791	25.94	149	791	1	650	1.0e-92	334	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
643920064	436	38.13	1	427	3	424	1.0e-103	370	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
643920065	274	39.08	1	274	2	284	6.0e-81	294	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
643920066	451	35.91	18	451	7	441	3.0e-88	319	COG0539	Ribosomal protein S1	541
643920069	527	44.44	1	313	1	313	4.0e-85	309	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
643920071	704	41.7	32	696	1	574	0.0e+00	558	COG1966	Carbon starvation protein CstA	575
643920074	642	34.36	9	621	4	586	2.0e-104	373	COG2604	Uncharacterized conserved protein	594
643920077	312	15.11	1	312	9	318	4.0e-07	48.8	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
643920078	364	19.02	21	319	2	293	4.0e-18	85.8	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
643920079	259	44.07	1	229	10	243	4.0e-68	251	COG3959	Transketolase, N-terminal subunit	243
643920080	291	28.05	1	287	9	310	3.0e-48	185	COG3958	Transketolase, C-terminal subunit	312
643920082	354	25.37	27	288	16	275	9.0e-21	94.7	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
643920084	241	27.02	3	240	7	249	5.0e-26	111	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643920085	309	17.95	23	300	17	313	1.0e-12	67.3	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
643920087	269	25.79	1	228	3	251	2.0e-25	109	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643920088	358	33.24	10	358	12	374	2.0e-74	272	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
643920089	317	26.39	1	275	2	282	6.0e-26	111	COG0223	Methionyl-tRNA formyltransferase	307
643920090	192	25.31	9	170	28	179	4.0e-13	68	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
643920092	314	22.35	1	314	2	330	1.0e-19	90.5	COG0859	ADP-heptose:LPS heptosyltransferase	334
643920101	625	28.55	1	600	1	521	7.0e-81	295	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
643920103	368	22.83	1	363	2	377	8.0e-25	108	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643920104	581	28.39	1	548	1	515	2.0e-78	286	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
643920109	563	28.3	1	557	1	510	2.0e-82	300	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
643920110	359	27.53	2	353	3	336	8.0e-42	164	COG1817	Predicted glycosyltransferase	346
643920111	354	28.03	1	342	3	340	3.0e-52	199	COG0673	Predicted dehydrogenase	342
643920115	366	40	3	366	1	372	4.0e-92	331	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
643920116	174	36.9	9	173	22	189	2.0e-42	165	COG0529	Adenylylsulfate kinase or related kinase	197
643920121	773	14.29	83	743	96	719	5.0e-24	107	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
643920122	206	22.77	1	187	1	219	1.0e-23	103	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
643920125	252	27.67	1	252	4	232	2.0e-39	155	COG1213	Choline kinase	239
643920128	740	49.05	2	569	1	568	0.0e+00	613	COG0550	DNA topoisomerase IA	570
643920129	134	37.01	3	129	2	128	4.0e-29	120	COG5015	Uncharacterized protein, pyridoxamine 5'-phosphate oxidase (PNPOx-like) family	132
643920130	279	36.86	1	271	45	316	5.0e-77	281	COG0502	Biotin synthase or related enzyme	335
643920131	280	26.39	23	278	27	295	5.0e-21	95.4	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
643920132	441	41.19	6	441	4	429	4.0e-104	371	COG1253	Hemolysin or related protein, contains CBS domains	429
643920134	164	51.55	1	161	2	160	1.0e-47	182	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
643920136	308	30.24	52	297	45	283	9.0e-35	141	COG1578	Uncharacterized conserved protein, contains ATP-grasp and redox domains	285
643920137	433	54.73	3	433	1	444	0.0e+00	503	COG2056	Predicted histidine transporter YuiF, NhaC family	444
643920138	313	54.95	4	204	1	202	7.0e-64	237	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
643920139	488	50.92	1	488	3	482	0.0e+00	597	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
643920140	227	48.9	1	225	2	220	2.0e-77	281	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
643920141	72	26.98	1	63	1	60	4.0e-07	46.4	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
643920143	237	22.07	21	164	10	146	1.0e-07	50	COG2010	Cytochrome c, mono- and diheme variants	150
643920149	331	28.72	3	293	1	288	3.0e-49	189	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
643920150	479	38.63	1	462	1	377	1.0e-107	383	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
643920151	859	32.86	383	775	124	542	8.0e-40	159	COG2189	Adenine specific DNA methylase Mod	590
643920153	331	45.37	4	324	2	323	4.0e-76	278	COG3943	Uncharacterized conserved protein	329
643920156	217	19.68	26	211	3	175	3.0e-27	115	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
643920157	243	36.12	1	242	1	263	3.0e-35	142	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
643920158	225	45.75	11	222	8	219	2.0e-49	188	COG0765	ABC-type amino acid transport system, permease component	222
643920159	235	63.95	1	233	9	240	4.0e-106	377	COG1126	ABC-type polar amino acid transport system, ATPase component	240
643920160	650	48.32	6	645	11	666	0.0e+00	763	COG0272	NAD-dependent DNA ligase	667
643920161	160	62.11	1	158	1	160	5.0e-60	223	COG1854	S-ribosylhomocysteine lyase LuxS, autoinducer biosynthesis	161
643920162	332	35.38	6	328	11	342	2.0e-77	282	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
643920163	332	22.03	25	300	20	302	7.0e-38	151	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
643920164	365	40.46	15	361	1	339	6.0e-106	377	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
643920167	406	33.5	5	406	7	401	3.0e-85	309	COG0303	Molybdopterin biosynthesis enzyme	404
643920168	195	55.28	1	195	1	193	2.0e-58	219	COG0807	GTP cyclohydrolase II	193
643920169	229	34.8	17	216	1	197	4.0e-47	181	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
643920170	88	50	1	82	1	82	2.0e-21	94.2	COG0298	Hydrogenase maturation factor	82
643920171	463	67.97	1	462	1	462	0.0e+00	782	COG0114	Fumarate hydratase class II	462
643920173	350	28.41	1	349	1	313	6.0e-51	194	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643920174	372	34.74	1	367	6	383	2.0e-90	326	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
643920175	367	31.11	17	364	8	365	3.0e-49	189	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
643920176	299	42.86	1	290	1	291	3.0e-49	188	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
643920177	399	32.79	20	385	6	311	2.0e-45	177	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
643920178	257	52.99	1	251	2	249	1.0e-92	333	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
643920179	231	55.32	1	231	3	237	8.0e-86	310	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
643920180	139	56.3	4	137	3	137	9.0e-48	182	COG0102	Ribosomal protein L13	148
643920181	129	55.04	1	129	3	130	8.0e-41	159	COG0103	Ribosomal protein S9	130
643920183	607	29.87	1	604	1	542	8.0e-80	291	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
643920184	138	26.35	1	138	5	151	3.0e-09	54.2	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
643920185	113	33.71	11	99	14	102	4.0e-14	69.9	COG3162	Uncharacterized membrane protein, DUF485 family	102
643920186	549	50.94	29	541	3	529	2.0e-130	460	COG4147	Na+(or H+)/acetate symporter ActP	529
643920187	343	27.64	14	333	6	314	3.0e-27	116	COG1275	Tellurite resistance protein TehA and related permeases	329
643920188	617	36.59	93	616	179	730	0.0e+00	500	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
643920192	658	59.73	1	656	2	656	0.0e+00	983	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
643920193	367	53.92	25	349	1	332	8.0e-118	416	COG1135	ABC-type methionine transport system, ATPase component	339
643920194	237	50	28	236	13	222	5.0e-59	221	COG2011	ABC-type methionine transport system, permease component	222
643920195	272	48.71	2	269	5	267	1.0e-75	276	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
643920196	531	41.39	1	529	3	528	0.0e+00	523	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
643920197	165	26.04	70	165	9	101	7.0e-08	50.4	COG2863	Cytochrome c553	121
643920199	312	48.4	2	310	112	423	6.0e-105	374	COG0151	Phosphoribosylamine-glycine ligase	428
643920200	151	22.67	1	149	1	148	7.0e-06	43.6	COG1714	Uncharacterized membrane protein YckC, RDD family	172
643920203	225	32.23	12	222	2	210	1.0e-38	153	COG1926	Predicted phosphoribosyltransferase	220
643920204	715	45.45	4	714	7	691	0.0e+00	689	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
643920205	250	55.56	1	241	2	239	4.0e-95	341	COG1126	ABC-type polar amino acid transport system, ATPase component	240
643920206	238	36.77	9	231	11	221	1.0e-40	159	COG0765	ABC-type amino acid transport system, permease component	222
643920207	257	25.75	1	255	4	267	1.0e-28	120	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
643920208	386	46.84	1	386	6	395	7.0e-130	457	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
643920209	1322	18.4	335	744	89	488	9.0e-16	80.1	COG0286	Type I restriction-modification system, DNA methylase subunit	489
643920210	82	24.71	3	82	6	90	1.0e-08	51.8	COG2921	Putative lipoic acid-binding regulatory protein	90
643920211	137	31.85	2	133	8	131	1.0e-27	115	COG0824	Acyl-CoA thioesterase FadM	137
643920213	352	41.4	1	340	14	345	2.0e-97	349	COG2957	Agmatine/peptidylarginine deiminase	346
643920215	333	42.43	1	329	2	331	3.0e-96	345	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
643920216	433	35.47	3	433	2	425	3.0e-107	382	COG0124	Histidyl-tRNA synthetase	429
643920217	67	50	1	67	1	70	1.0e-19	88	COG0254	Ribosomal protein L31	75
643920218	272	41.61	4	272	9	274	1.0e-66	246	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
643920219	228	30.8	1	227	22	257	4.0e-41	161	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
643920223	403	39	11	402	5	393	3.0e-91	328	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
643920224	800	35.97	91	800	3	709	0.0e+00	636	COG2217	Cation transport ATPase	713
643920226	556	20.16	19	527	2	454	7.0e-28	119	COG0277	FAD/FMN-containing dehydrogenase	459
643920228	892	32.31	4	888	27	917	0.0e+00	635	COG0474	Magnesium-transporting ATPase (P-type)	917
643920229	208	48.28	1	194	3	204	3.0e-62	231	COG0605	Superoxide dismutase	204
643920233	516	27.96	9	516	5	555	7.0e-69	255	COG0497	DNA repair ATPase RecN	557
643920234	282	35.84	7	280	3	281	9.0e-63	233	COG0061	NAD kinase	281
643920239	381	17.38	7	376	15	387	1.0e-14	74.5	COG2814	Predicted arabinose efflux permease, MFS family	394
643920240	148	46.94	1	147	1	146	6.0e-31	126	COG0359	Ribosomal protein L9	148
643920241	178	57.3	1	178	1	175	9.0e-67	246	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
643920242	446	52.94	7	446	4	444	0.0e+00	534	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
643920243	294	36.7	1	293	2	298	8.0e-80	290	COG1159	GTPase Era, involved in 16S rRNA processing	298
643920244	331	27.53	37	322	25	297	1.0e-40	160	COG3034	Murein L,D-transpeptidase YafK	298
643920245	205	40.49	1	203	2	194	6.0e-46	177	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
643920246	453	21.47	25	387	30	394	2.0e-29	124	COG2814	Predicted arabinose efflux permease, MFS family	394
643920247	257	33.46	7	256	2	243	1.0e-36	146	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
643920248	401	59.5	1	400	1	396	0.0e+00	582	COG0282	Acetate kinase	396
643920249	333	46.25	3	333	1	326	6.0e-93	334	COG0280	Phosphotransacetylase	327
643920250	422	30.92	68	417	80	427	2.0e-60	227	COG0166	Glucose-6-phosphate isomerase	446
643920251	331	52.41	2	329	1	332	9.0e-109	386	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
643920252	96	45.26	1	95	2	94	5.0e-12	62.8	COG0776	Bacterial nucleoid DNA-binding protein	94
643920254	234	41.2	6	234	10	237	8.0e-46	177	COG2859	Uncharacterized protein	237
643920255	190	23.59	2	189	40	224	1.0e-15	76.6	COG1040	Predicted amidophosphoribosyltransferases	225
643920256	194	30.81	1	187	4	201	8.0e-31	126	COG0125	Thymidylate kinase	208
643920257	166	51.23	1	162	1	158	3.0e-54	204	COG0669	Phosphopantetheine adenylyltransferase	159
643920258	334	45.06	1	333	2	343	2.0e-108	385	COG0418	Dihydroorotase	344
643920259	455	30.21	1	455	4	461	6.0e-79	288	COG1109	Phosphomannomutase	464
643920260	407	21.4	1	407	3	408	7.0e-38	151	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
643920263	358	25.98	1	347	2	330	3.0e-36	145	COG0859	ADP-heptose:LPS heptosyltransferase	334
643920264	302	24.92	3	299	14	308	1.0e-47	183	COG1560	Lauroyl/myristoyl acyltransferase	308
643920265	333	29.53	4	332	1	333	9.0e-40	157	COG0859	ADP-heptose:LPS heptosyltransferase	334
643920266	485	33.13	1	483	1	489	7.0e-84	304	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
643920269	680	38.68	1	679	2	690	0.0e+00	636	COG0751	Glycyl-tRNA synthetase, beta subunit	691
643920271	539	25.4	166	538	40	407	2.0e-35	144	COG0840	Methyl-accepting chemotaxis protein	408
643920272	317	37.93	2	311	4	319	1.0e-72	266	COG0042	tRNA-dihydrouridine synthase	323
643920275	555	37.46	11	551	1	588	5.0e-113	402	COG0465	ATP-dependent Zn proteases	596
643920276	423	29.95	2	408	1	420	2.0e-91	329	COG0621	tRNA A37 methylthiotransferase MiaB	437
643920277	553	20.06	227	546	19	308	5.0e-18	86.5	COG0668	Small-conductance mechanosensitive channel	316
643920278	340	47.98	7	339	12	357	1.0e-108	386	COG0337	3-dehydroquinate synthetase	360
643920279	117	35.58	4	107	3	106	2.0e-16	78.2	COG2076	Multidrug transporter EmrE and related cation transporters	106
643920280	107	35.58	4	107	2	104	7.0e-13	65.9	COG2076	Multidrug transporter EmrE and related cation transporters	106
643920281	388	42.28	4	388	1	393	7.0e-112	397	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
643920282	86	54.26	1	85	1	94	3.0e-23	99.8	COG0234	Co-chaperonin GroES (HSP10)	96
643920283	546	49.54	1	528	1	519	0.0e+00	475	COG0459	Chaperonin GroEL (HSP60 family)	524
643920284	371	55.07	4	368	3	363	0.0e+00	480	COG0409	Hydrogenase maturation factor	364
643920286	276	25.56	2	254	15	249	2.0e-36	146	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
643920287	76	43.84	1	73	1	73	1.0e-13	68	COG1551	sRNA-binding carbon storage regulator CsrA	73
643920288	251	33.33	2	251	6	257	6.0e-45	174	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
643920289	152	57.62	1	151	5	153	5.0e-46	176	COG0691	tmRNA-binding protein	153
643920290	157	38.16	4	149	59	210	1.0e-23	102	COG0811	Biopolymer transport protein ExbB/TolQ	216
643920291	129	28.12	5	129	11	136	3.0e-17	80.6	COG0848	Biopolymer transport protein ExbD	137
643920295	230	58.11	11	230	1	222	4.0e-89	320	COG0692	Uracil DNA glycosylase	223
643920296	97	37.23	4	97	3	95	2.0e-14	70.2	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
643920298	157	18.95	1	149	2	148	7.0e-10	56.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
643920299	401	45.78	1	400	2	447	5.0e-113	401	COG0527	Aspartokinase	447
643920302	376	41.95	115	376	5	265	5.0e-69	255	COG0294	Dihydropteroate synthase	274
643920304	313	30.18	49	312	5	283	4.0e-36	145	COG1408	Predicted phosphohydrolase, MPP superfamily	284
643920307	258	21.46	1	253	3	254	6.0e-26	111	COG0388	Predicted amidohydrolase	274
643920308	616	45.45	255	615	1	342	1.0e-80	294	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
643920309	1171	47.65	12	1169	1	1134	0.0e+00	1194	COG0587	DNA polymerase III, alpha subunit	1139
643920311	250	34.24	1	249	3	247	1.0e-50	193	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
643920312	176	45.73	5	166	9	169	1.0e-46	179	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
643920313	161	28.93	1	153	2	159	8.0e-24	103	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
643920314	152	20.53	4	149	1	148	9.0e-21	93	COG0314	Molybdopterin synthase catalytic subunit	149
643920315	73	32.14	1	73	1	84	5.0e-08	49.5	COG1977	Molybdopterin converting factor, small subunit	84
643920317	124	56.45	1	121	3	126	1.0e-36	145	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
643920318	103	54.37	1	103	1	103	2.0e-29	120	COG0261	Ribosomal protein L21	103
643920319	85	73.81	1	84	1	84	3.0e-33	133	COG0211	Ribosomal protein L27	87
643920320	366	49.18	1	360	2	338	3.0e-120	425	COG0536	GTPase involved in cell partioning and DNA repair	369
643920322	300	41.56	1	297	2	307	4.0e-68	251	COG0223	Methionyl-tRNA formyltransferase	307
643920323	210	26.76	6	209	1	210	1.0e-27	116	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
643920324	261	44.27	1	260	1	253	6.0e-55	207	COG1192	Cellulose biosynthesis protein BcsQ	259
643920325	297	42.53	31	245	2	216	1.0e-29	123	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
643920326	141	28.79	9	140	8	139	1.0e-11	62.2	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
643920327	171	26.05	27	145	8	126	1.0e-09	56.4	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
643920328	178	27.17	5	175	7	178	3.0e-10	58.3	COG0712	FoF1-type ATP synthase, delta subunit	178
643920329	504	68.34	4	502	2	500	0.0e+00	809	COG0056	FoF1-type ATP synthase, alpha subunit	504
643920330	294	43.69	6	294	1	287	2.0e-70	258	COG0224	FoF1-type ATP synthase, gamma subunit	287
643920331	471	72.92	5	469	2	467	0.0e+00	812	COG0055	FoF1-type ATP synthase, beta subunit	468
643920332	130	39.06	1	127	1	128	2.0e-22	98.4	COG0355	FoF1-type ATP synthase, epsilon subunit	135
643920333	188	27.57	17	181	21	205	7.0e-20	90.4	COG0811	Biopolymer transport protein ExbB/TolQ	216
643920334	130	42.28	6	128	11	132	4.0e-26	110	COG0848	Biopolymer transport protein ExbD	137
643920336	426	23.38	6	426	1	421	2.0e-49	189	COG0823	Periplasmic component of the Tol biopolymer transport system	425
643920337	174	28.49	1	174	6	189	1.0e-27	116	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
643920338	294	20.28	101	294	50	260	1.0e-09	57.3	COG1729	Periplasmic TolA-binding protein (function unknown)	262
643920339	171	42.2	1	171	2	173	2.0e-36	145	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
643920342	307	24.84	1	304	1	293	3.0e-32	132	COG0501	Zn-dependent protease with chaperone function	302
643920343	180	55.25	1	180	15	194	3.0e-69	254	COG0302	GTP cyclohydrolase I	195
643920344	299	41.08	3	299	2	293	3.0e-62	232	COG4866	Uncharacterized protein	294
643920346	126	47.62	1	126	1	126	1.0e-31	128	COG1516	Flagellin-specific chaperone FliS	132
643920348	122	28.69	1	122	1	120	1.0e-13	68.4	COG1334	Uncharacterized conserved protein, FlaG/YvyC family	120
643920349	409	18.29	1	400	17	414	9.0e-24	105	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
643920351	222	39.91	4	220	1	222	1.0e-52	199	COG1136	ABC-type lipoprotein export system, ATPase component	226
643920352	409	31.28	118	302	31	222	4.0e-33	135	COG0220	tRNA G46 methylase TrmB	227
643920353	421	30.11	70	418	2	343	8.0e-40	158	COG3401	Fibronectin type 3 domain	343
643920354	340	37.29	11	297	2	287	3.0e-54	205	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
643920355	372	35.69	1	348	4	365	2.0e-52	200	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
643920361	257	36.88	1	257	14	268	3.0e-51	195	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
643920363	195	30.89	1	186	2	185	2.0e-30	125	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
643920365	268	52.85	9	268	1	263	2.0e-89	322	COG0413	Ketopantoate hydroxymethyltransferase	268
643920366	333	61.54	1	324	1	325	0.0e+00	474	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
643920367	874	22.74	1	318	1	320	3.0e-20	94.8	COG1344	Flagellin and related hook-associated protein FlgL	360
643920368	583	58.77	1	580	1	584	0.0e+00	873	COG0173	Aspartyl-tRNA synthetase	585
643920369	190	33.87	3	187	1	178	2.0e-30	125	COG0563	Adenylate kinase or related kinase	178
643920370	173	59.88	1	172	1	170	3.0e-55	207	COG0221	Inorganic pyrophosphatase	171
643920371	339	36.59	8	334	4	325	6.0e-80	291	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
643920372	206	26.25	23	182	3	154	6.0e-20	91.2	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
643920373	425	46.49	54	423	9	378	4.0e-90	325	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
643920374	249	38.2	3	232	2	219	6.0e-22	98.1	COG0785	Cytochrome c biogenesis protein CcdA	220
643920375	155	26.58	1	147	14	166	2.0e-07	48.8	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
643920377	546	56.62	6	546	1	532	0.0e+00	788	COG0504	CTP synthase (UTP-ammonia lyase)	533
643920378	526	35.89	28	469	6	454	4.0e-77	282	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
643920379	806	25.44	12	806	11	725	1.0e-84	308	COG1033	Predicted exporter protein, RND superfamily	727
643920380	191	27.18	3	187	8	202	1.0e-28	119	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
643920381	232	35.34	1	232	1	229	3.0e-49	188	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
643920382	625	47.77	24	623	22	625	0.0e+00	753	COG1154	Deoxyxylulose-5-phosphate synthase	627
643920383	289	24.48	101	287	44	227	3.0e-14	72.3	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
643920384	344	42.01	7	343	1	338	5.0e-79	288	COG1536	Flagellar motor switch protein FliG	339
643920385	576	40.6	1	562	3	545	6.0e-116	411	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
643920386	366	36.92	29	366	20	354	3.0e-75	275	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
643920388	419	21.53	19	412	43	442	1.0e-32	134	COG1538	Outer membrane protein TolC	457
643920389	1039	27.4	6	1033	7	1009	0.0e+00	613	COG0841	Multidrug efflux pump subunit AcrB	1009
643920390	342	23.42	16	338	37	366	1.0e-24	107	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643920392	157	50.96	1	157	2	157	5.0e-48	183	COG0315	Molybdenum cofactor biosynthesis enzyme	157
643920393	380	26.1	85	379	112	406	3.0e-23	103	COG0840	Methyl-accepting chemotaxis protein	408
643920394	157	32.31	25	153	6	135	4.0e-18	84.6	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
643920395	589	32.01	1	353	3	328	9.0e-69	255	COG0270	Site-specific DNA-cytosine methylase	328
643920402	121	35.11	9	99	1	93	3.0e-09	54	COG0789	DNA-binding transcriptional regulator, MerR family	124
643920406	441	45.2	13	437	8	387	2.0e-105	376	COG3004	Na+/H+ antiporter NhaA	390
643920407	89	43.82	1	89	2	90	5.0e-21	92.6	COG1862	Preprotein translocase subunit YajC	97
643920408	525	42.89	1	504	2	495	6.0e-121	428	COG0342	Preprotein translocase subunit SecD	506
643920409	323	42.86	1	306	1	305	7.0e-72	264	COG0341	Preprotein translocase subunit SecF	305
643920411	812	49.45	1	811	3	814	0.0e+00	945	COG0495	Leucyl-tRNA synthetase	814
643920413	391	19.87	234	382	22	171	5.0e-08	52.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
643920414	379	28.5	1	374	8	420	2.0e-68	253	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
643920416	146	36.13	6	123	11	129	2.0e-17	81.9	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
643920417	1004	35.39	18	975	30	1078	0.0e+00	832	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
643920418	271	45.97	1	246	1	243	9.0e-68	250	COG1692	Calcineurin-like phosphoesterase	266
643920419	618	39.96	1	446	6	441	0.0e+00	466	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
643920422	177	42.96	22	154	21	154	1.0e-22	99.2	COG1267	Phosphatidylglycerophosphatase A	160
643920423	394	24.59	1	355	22	382	6.0e-47	182	COG2046	ATP sulfurylase (sulfate adenylyltransferase)	397
643920425	382	54.78	222	378	3	159	4.0e-55	209	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
643920426	518	31.97	203	518	64	379	5.0e-32	132	COG0840	Methyl-accepting chemotaxis protein	408
643920427	429	26.78	8	425	3	386	2.0e-59	223	COG0247	Fe-S oxidoreductase	388
643920428	456	36.45	18	445	7	416	4.0e-109	388	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
643920432	114	34.21	1	114	1	113	2.0e-20	91.1	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
643920433	163	45.7	7	157	1	151	9.0e-47	179	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
643920435	158	46.48	13	154	14	155	9.0e-44	169	COG1607	Acyl-CoA hydrolase	157
643920436	360	30.4	1	358	1	357	1.0e-63	237	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
643920437	163	34.62	10	163	1	156	4.0e-32	130	COG0835	Chemotaxis signal transduction protein	165
643920438	798	41.42	1	647	3	711	0.0e+00	616	COG0643	Chemotaxis protein histidine kinase CheA	716
643920439	321	31.76	1	170	2	158	6.0e-30	125	COG0835	Chemotaxis signal transduction protein	165
643920440	171	22.22	5	170	68	237	5.0e-08	50.6	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
643920442	336	41.88	1	336	1	349	8.0e-98	350	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
643920443	65	34.85	1	65	3	68	9.0e-10	55.2	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
643920444	435	43.51	6	434	3	460	2.0e-125	443	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
643920445	254	36.76	1	251	1	253	4.0e-59	221	COG1291	Flagellar motor component MotA	266
643920446	276	24	1	240	1	243	2.0e-24	106	COG1360	Flagellar motor protein MotB	244
643920447	250	53.41	1	249	1	247	5.0e-70	257	COG1338	Flagellar biosynthetic protein FliP	248
643920450	218	50.49	11	213	3	206	9.0e-70	256	COG0177	Endonuclease III	211
643920453	316	28.62	11	313	15	332	1.0e-52	200	COG1559	Cell division protein YceG, involved in septum cleavage	342
643920454	315	43.04	5	309	1	308	1.0e-81	296	COG0039	Malate/lactate dehydrogenase	313
643920455	103	35.21	11	81	2	68	2.0e-08	50.9	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
643920456	375	36.27	6	375	5	361	3.0e-75	276	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
643920457	277	41.64	5	268	4	271	2.0e-75	276	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
643920458	187	31.44	1	180	2	194	9.0e-23	100	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
643920460	200	21.77	54	196	49	193	2.0e-06	45.7	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
643920462	209	41.04	14	179	10	160	4.0e-34	137	COG0437	Fe-S-cluster-containing dehydrogenase component	203
643920463	315	32.69	117	315	2	208	6.0e-29	121	COG2864	Cytochrome b subunit of formate dehydrogenase	218
643920464	260	35.23	1	259	2	265	1.0e-56	213	COG1526	Formate dehydrogenase assembly factor FdhD	266
643920466	279	30.82	1	278	3	286	2.0e-41	163	COG2996	Predicted RNA-binding protein, contains S1 domains,  virulence factor B family	287
643920468	305	57.33	4	300	2	300	1.0e-110	392	COG0031	Cysteine synthase	300
643920469	849	68.15	3	849	1	846	0.0e+00	1339	COG1049	Aconitase B	852
643920470	343	43.84	4	331	5	364	1.0e-89	323	COG1858	Cytochrome c peroxidase	364
643920471	159	52.17	18	152	1	136	2.0e-46	178	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
643920473	831	57.23	5	810	4	803	0.0e+00	984	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
643920475	432	44.27	1	431	5	457	2.0e-126	445	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643920476	341	53.82	3	337	1	334	3.0e-112	398	COG0136	Aspartate-semialdehyde dehydrogenase	334
643920477	152	41.84	6	146	4	134	7.0e-32	129	COG0394	Protein-tyrosine-phosphatase	139
643920478	108	22.58	6	95	5	97	1.0e-09	54.9	COG0607	Rhodanese-related sulfurtransferase	110
643920479	231	26.83	22	210	28	232	5.0e-17	81.6	COG1587	Uroporphyrinogen-III synthase	248
643920480	450	26.73	9	450	13	453	3.0e-39	156	COG0534	Na+-driven multidrug efflux pump	455
643920481	468	57.91	1	468	2	469	0.0e+00	657	COG1027	Aspartate ammonia-lyase	471
643920482	444	55.83	1	444	1	435	0.0e+00	478	COG2704	Anaerobic C4-dicarboxylate transporter	436
643920484	600	67.55	1	600	2	601	0.0e+00	993	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
643920485	291	31.72	5	280	20	309	2.0e-46	179	COG0616	Periplasmic serine protease, ClpP class	317
643920486	277	45.91	1	277	6	286	6.0e-97	347	COG0788	Formyltetrahydrofolate hydrolase	287
643920488	152	38.41	1	145	1	149	1.0e-39	155	COG3019	Uncharacterized conserved protein	149
643920489	353	29.76	66	349	20	292	1.0e-37	150	COG4974	Site-specific recombinase XerD	300
643920494	356	25.65	72	339	1	208	6.0e-19	88.5	COG1843	Flagellar hook assembly protein FlgD	222
643920496	599	63.5	1	599	2	601	0.0e+00	962	COG1217	Predicted membrane GTPase involved in stress response	603
643920497	790	37.16	38	790	1	654	0.0e+00	602	COG0209	Ribonucleotide reductase alpha subunit	696
643920499	406	26.16	48	405	96	436	3.0e-37	150	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
643920500	416	40.69	1	413	3	437	8.0e-116	410	COG1570	Exonuclease VII, large subunit	440
643920501	596	57.75	1	442	5	449	0.0e+00	636	COG5016	Pyruvate/oxaloacetate carboxyltransferase	472
643920503	853	48.47	3	852	9	879	0.0e+00	989	COG0013	Alanyl-tRNA synthetase	879
643920504	945	26.77	16	513	8	456	1.0e-65	245	COG0277	FAD/FMN-containing dehydrogenase	459
643920505	372	30.48	1	372	13	409	6.0e-71	261	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643920506	234	24.34	6	219	7	221	2.0e-07	49.9	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
643920507	294	31.63	17	285	17	304	7.0e-40	157	COG0196	FAD synthase	304
643920508	242	43.44	1	241	3	245	1.0e-60	226	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
643920510	443	50.59	1	423	1	411	0.0e+00	528	COG1004	UDP-glucose 6-dehydrogenase	414
643920511	303	43.09	1	294	6	316	6.0e-96	344	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
643920512	200	26.34	1	193	4	208	3.0e-15	75.3	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
643920513	438	64.54	16	436	1	422	0.0e+00	660	COG1158	Transcription termination factor Rho	422
643920514	259	35.38	4	256	6	256	9.0e-62	230	COG0796	Glutamate racemase	269
643920516	433	25.66	98	431	3	335	3.0e-27	116	COG0642	Signal transduction histidine kinase	336
643920517	223	37.39	1	221	1	229	9.0e-48	183	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643920518	450	63.53	2	447	1	445	0.0e+00	699	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
643920519	427	44.67	26	427	1	379	6.0e-115	407	COG0372	Citrate synthase	390
643920520	173	24.39	1	171	4	208	2.0e-15	75.4	COG2834	Outer membrane lipoprotein-sorting protein	211
643920521	171	28.99	1	168	1	159	3.0e-14	71.4	COG2862	Uncharacterized membrane protein YqhA	169
643920522	338	47.51	1	336	8	348	1.0e-104	373	COG0407	Uroporphyrinogen-III decarboxylase	352
643920523	852	56.35	1	837	1	822	0.0e+00	997	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
643920524	406	34.98	9	406	8	408	9.0e-75	274	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
643920525	289	17.41	1	280	16	327	3.0e-08	53.1	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
643920526	510	48.84	1	510	3	515	0.0e+00	635	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
643920527	355	21.25	1	354	1	363	4.0e-27	115	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
643920528	190	47.62	1	182	2	189	3.0e-52	198	COG0193	Peptidyl-tRNA hydrolase	190
643920529	178	26.14	1	87	3	90	6.0e-15	73.8	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
643920530	334	22.05	6	334	3	238	1.0e-26	114	COG0176	Transaldolase	239
643920531	206	41.55	1	206	5	211	1.0e-48	185	COG0560	Phosphoserine phosphatase	212
643920532	807	48.26	1	803	2	740	0.0e+00	704	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
643920533	736	41.84	5	727	16	743	0.0e+00	783	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
643920536	225	32.26	4	218	19	231	5.0e-31	128	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
643920537	109	28.57	6	109	1	105	2.0e-10	57.5	COG1687	Branched-chain amino acid transport protein AzlD	106
643920538	113	46.02	1	111	2	114	1.0e-27	114	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
643920540	245	40.74	6	212	1	216	5.0e-63	234	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
643920541	451	28.6	2	439	1	416	2.0e-68	253	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
643920542	275	32.44	1	262	5	266	3.0e-33	135	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
643920546	204	31.58	2	203	1	205	1.0e-22	100	COG0778	Nitroreductase	207
643920547	325	21.6	1	298	4	338	4.0e-37	148	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
643920548	557	32.37	1	549	1	548	9.0e-96	344	COG0358	DNA primase (bacterial type)	568
643920550	143	46.26	1	139	1	147	3.0e-37	147	COG0328	Ribonuclease HI	154
643920551	224	48.02	2	224	7	233	4.0e-65	241	COG0571	dsRNA-specific ribonuclease	235
643920552	356	51.24	1	356	2	364	2.0e-130	459	COG0082	Chorismate synthase	369
643920553	304	23.28	3	277	2	297	2.0e-17	83.1	COG3980	Spore coat polysaccharide biosynthesis protein SpsG, predicted glycosyltransferase	318
643920554	456	42.2	2	454	4	435	3.0e-99	355	COG0733	Na+-dependent transporter, SNF family	439
643920557	135	26.51	11	93	6	88	1.0e-07	49.5	COG3062	Cytoplasmic chaperone NapD for the signal peptide of periplasmic nitrate reductase NapAB	94
643920560	174	30.2	4	151	3	148	1.0e-22	99.7	COG3043	Nitrate reductase cytochrome c-type subunit	155
643920564	319	30.22	3	184	2	165	6.0e-25	108	COG0835	Chemotaxis signal transduction protein	165
643920565	567	36.41	5	565	4	562	3.0e-116	412	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
643920566	644	36.96	1	612	8	612	0.0e+00	524	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
643920567	230	24.67	14	227	3	226	2.0e-19	89.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643920568	99	52.08	1	96	1	96	2.0e-26	110	COG4378	Uncharacterized protein	103
643920569	149	37.69	20	149	13	142	5.0e-29	120	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
643920570	152	26.35	1	141	4	148	6.0e-18	83.5	COG2236	Hypoxanthine phosphoribosyltransferase	192
643920571	351	41.62	11	351	21	366	7.0e-102	364	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
643920575	674	30.84	4	671	1	642	2.0e-92	334	COG0210	Superfamily I DNA or RNA helicase	655
643920576	130	33.33	6	130	18	146	1.0e-17	82.2	COG1699	Flagellar assembly factor FliW	146
643920577	879	49.05	7	879	3	877	0.0e+00	1074	COG0525	Valyl-tRNA synthetase	877
643920578	354	21.71	8	354	15	346	2.0e-15	77.2	COG0628	Predicted PurR-regulated permease PerM	355
643920579	460	25.89	5	369	1	344	5.0e-48	185	COG0348	Polyferredoxin	386
643920582	367	60.59	1	367	1	372	0.0e+00	491	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
643920583	452	39.39	1	452	33	485	2.0e-124	439	COG0260	Leucyl aminopeptidase	485
643920584	196	25.39	3	190	16	208	7.0e-26	110	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
643920585	118	43.97	3	115	11	126	4.0e-36	143	COG0229	Peptide methionine sulfoxide reductase MsrB	140
643920586	186	28.88	7	186	21	207	2.0e-17	82.6	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
643920587	240	35.77	1	240	1	244	5.0e-53	200	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
643920588	341	19.78	1	335	2	360	3.0e-17	83.1	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
643920589	240	33.6	1	240	2	245	4.0e-12	65	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
643920590	200	32.12	1	183	2	192	2.0e-34	139	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
643920591	113	36.63	8	107	6	106	3.0e-22	97.2	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
643920592	250	55.83	2	239	8	246	8.0e-86	310	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
643920594	125	22.86	7	111	4	96	2.0e-06	45	COG0727	Fe-S-cluster containining protein	132
643920595	230	28.95	1	222	18	243	2.0e-38	152	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
643920599	638	21.8	141	638	69	582	4.0e-52	199	COG2604	Uncharacterized conserved protein	594
643920600	184	25.68	2	184	16	192	4.0e-24	104	COG3963	Phospholipid N-methyltransferase	194
643920601	309	60.26	1	308	2	313	4.0e-119	421	COG0462	Phosphoribosylpyrophosphate synthetase	314
643920602	189	43.03	32	189	2	158	1.0e-41	162	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
643920605	250	24.23	72	245	7	199	5.0e-13	68.5	COG1573	Uracil-DNA glycosylase	202
643920606	409	10.56	37	384	41	377	2.0e-12	67	COG5659	SRSO17 transposase	385
643920607	223	22.27	6	214	12	221	1.0e-18	87	COG1451	Predicted metal-dependent hydrolase	223
643920608	304	22.56	4	295	2	287	4.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
643920609	702	41.47	8	636	2	644	0.0e+00	525	COG0210	Superfamily I DNA or RNA helicase	655
643920610	257	48.88	1	254	4	267	3.0e-59	221	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
643920611	698	36.48	1	698	1	699	0.0e+00	600	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
643920612	473	51.27	1	470	1	471	0.0e+00	586	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
643920614	108	37.14	4	105	7	111	9.0e-16	75.3	COG0594	RNase P protein component	117
643920615	69	39.13	1	69	5	73	9.0e-16	75.4	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
643920617	536	45.45	244	533	17	312	5.0e-65	242	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
643920618	231	25.67	1	185	1	165	2.0e-13	69.1	COG1847	Predicted RNA-binding protein Jag, conains KH and R3H domains	208
643920619	461	41.27	6	461	4	454	3.0e-124	438	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
643920622	439	57.04	5	437	3	432	0.0e+00	588	COG0001	Glutamate-1-semialdehyde aminotransferase	432
643920623	390	36.18	8	390	10	386	2.0e-96	346	COG0754	Glutathionylspermidine synthase	387
643920626	443	65.26	15	438	3	427	0.0e+00	685	COG0422	Thiamine biosynthesis protein ThiC	432
643920627	371	44.81	77	315	36	265	4.0e-56	212	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
643920628	286	26.26	6	276	10	297	6.0e-28	118	COG0611	Thiamine monophosphate kinase	317
643920629	275	46.76	1	274	1	277	4.0e-80	291	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
643920630	331	43.98	1	331	23	323	1.0e-92	333	COG0379	Quinolinate synthase	324
643920631	260	22.1	4	260	8	232	6.0e-28	118	COG0688	Phosphatidylserine decarboxylase	239
643920632	237	33.77	7	225	14	238	3.0e-43	168	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
643920633	431	25.51	124	412	16	296	2.0e-22	100	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
643920634	183	34.22	1	173	2	188	7.0e-25	107	COG0693	Putative intracellular protease/amidase	188
643920635	187	50.77	1	130	2	131	3.0e-40	158	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
643920636	307	50.32	1	307	2	286	1.0e-99	355	COG0191	Fructose/tagatose bisphosphate aldolase	286
643920637	271	27.39	44	271	79	307	7.0e-10	58.2	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
643920638	512	27.92	1	502	100	497	2.0e-120	426	COG3303	Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit	501
643920640	169	25	17	166	17	179	5.0e-27	113	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
643920641	209	49.52	1	209	4	208	7.0e-51	193	COG2860	Uncharacterized membrane protein YeiH	209
643920643	325	21.56	8	172	2	153	4.0e-16	79.1	COG4940	Competence protein ComGF	154
643920646	340	41.86	6	340	3	339	4.0e-89	321	COG0309	Hydrogenase maturation factor	339
643920649	451	44.24	18	450	1	410	0.0e+00	477	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
643920651	212	32.67	13	212	4	201	3.0e-26	111	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
643920654	338	53.73	5	337	14	347	8.0e-109	386	COG2089	Sialic acid synthase SpsE, contains C-terminal SAF domain	347
643920657	252	46.01	1	250	1	260	8.0e-81	293	COG0708	Exonuclease III	261
643920658	152	34.44	4	150	4	153	1.0e-26	112	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
643920659	178	34.16	1	158	1	151	2.0e-08	52.7	COG1988	Membrane-bound metal-dependent hydrolase YbcI, DUF457 family	190
643920660	260	23.51	9	258	1	264	2.0e-21	96.2	COG0575	CDP-diglyceride synthetase	265
643920661	374	40.62	1	374	4	380	5.0e-103	367	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
643920663	318	27.1	1	318	4	322	6.0e-56	211	COG0598	Mg2+ and Co2+ transporter CorA	322
643920664	403	51.12	8	401	1	393	0.0e+00	463	COG0126	3-phosphoglycerate kinase	395
643920668	352	46.59	1	352	4	365	1.0e-95	343	COG1706	Flagellar basal body P-ring protein FlgI	365
643920670	252	36.78	1	249	2	255	5.0e-62	231	COG0171	NH3-dependent NAD+ synthetase	268
643920671	376	32.98	1	368	3	367	4.0e-70	259	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
643920672	300	29.22	4	299	5	328	4.0e-48	185	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
643920673	239	22.54	8	239	1	242	5.0e-14	71.3	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
643920674	128	34.4	7	128	13	136	6.0e-21	93	COG0848	Biopolymer transport protein ExbD	137
643920677	572	55.05	1	570	11	572	0.0e+00	737	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
643920681	246	35.29	1	236	1	232	5.0e-28	118	COG2836	Sulfite exporter TauE/SafE	232
643920682	467	47.45	2	467	1	464	0.0e+00	562	COG0215	Cysteinyl-tRNA synthetase	464
643920683	505	23.49	1	133	1	166	1.0e-19	91.6	COG1495	Disulfide bond formation protein DsbB	170
643920686	459	43.45	8	457	1	455	2.0e-109	389	COG0277	FAD/FMN-containing dehydrogenase	459
643920687	156	47.02	1	149	2	146	1.0e-42	165	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
643920688	267	54.65	4	260	1	258	4.0e-95	341	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
643920689	412	60.49	8	412	2	406	0.0e+00	585	COG1219	ATP-dependent protease Clp, ATPase subunit	408
643920690	344	62.31	7	340	2	337	8.0e-121	426	COG1077	Actin-like ATPase involved in cell morphogenesis	342
643920691	271	22.78	1	240	4	255	2.0e-12	66.9	COG1792	Cell shape-determining protein MreC	284
643920692	383	56.46	29	383	3	351	0.0e+00	475	COG1740	Ni,Fe-hydrogenase I small subunit	355
643920693	578	50.53	3	569	2	544	0.0e+00	664	COG0374	Ni,Fe-hydrogenase I large subunit	545
643920694	221	35.32	9	217	12	227	1.0e-47	182	COG1969	Ni,Fe-hydrogenase I cytochrome b subunit	227
643920695	178	32.5	1	159	2	158	2.0e-26	112	COG0680	Ni,Fe-hydrogenase maturation factor	160
643920698	237	42.19	1	236	6	237	4.0e-61	228	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
643920700	477	21.76	215	467	25	277	3.0e-18	86.7	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
643920702	295	47.67	1	295	2	300	2.0e-106	378	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
643920704	287	37.89	5	287	12	295	9.0e-57	213	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
643920705	576	22.69	140	560	80	482	1.0e-32	134	COG0464	AAA+-type ATPase, SpoVK/Ycf46/Vps4 family	494
643920706	446	43.92	4	445	9	437	7.0e-89	321	COG0733	Na+-dependent transporter, SNF family	439
643920709	399	33.5	6	399	14	405	7.0e-78	284	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
643920710	72	28.77	1	70	5	77	2.0e-06	44.1	COG0425	TusA-related sulfurtransferase	78
643920712	493	69.29	1	493	199	693	0.0e+00	721	COG0480	Translation elongation factor EF-G, a GTPase	697
643920714	155	65.54	1	148	1	148	5.0e-54	203	COG0049	Ribosomal protein S7	148
643920715	129	73.98	1	123	7	129	2.0e-46	177	COG0048	Ribosomal protein S12	129
643920716	2881	47.14	1398	2217	8	808	0.0e+00	809	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
643920717	124	65.32	1	124	1	124	5.0e-29	119	COG0222	Ribosomal protein L7/L12	124
643920718	160	36.2	1	160	3	165	5.0e-29	120	COG0244	Ribosomal protein L10	175
643920719	234	60.35	3	228	2	228	2.0e-74	272	COG0081	Ribosomal protein L1	228
643920720	141	67.14	2	141	1	140	3.0e-51	193	COG0080	Ribosomal protein L11	141
643920721	176	47.98	5	175	5	177	1.0e-43	168	COG0250	Transcription antitermination factor NusG	178
643920724	56	54	4	53	1	50	9.0e-10	55.2	COG0267	Ribosomal protein L33	50
643920725	399	79.95	1	399	1	394	0.0e+00	706	COG0050	Translation elongation factor EF-Tu, a GTPase	394
643920730	651	20.9	25	623	1	584	2.0e-20	94.6	COG4206	Outer membrane cobalamin receptor protein	608
643920732	226	24.75	1	188	1	184	2.0e-15	76.1	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
643920733	523	49.08	302	518	1	217	2.0e-43	170	COG1418	HD superfamily phosphodieaserase, includes HD domain of RNase Y	222
643920734	361	41.4	2	361	1	370	9.0e-102	363	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
643920737	327	17.85	1	297	2	290	2.0e-16	80.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
643920739	272	26.18	1	217	1	228	2.0e-22	99.5	COG0223	Methionyl-tRNA formyltransferase	307
643920742	342	58.91	3	332	1	317	0.0e+00	469	COG1088	dTDP-D-glucose 4,6-dehydratase	340
643920743	292	54.67	1	289	1	284	4.0e-103	367	COG1209	dTDP-glucose pyrophosphorylase	286
643920744	431	25.51	2	343	3	286	1.0e-22	101	COG1442	Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase	325
643920745	374	23.02	10	371	1	381	5.0e-28	118	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643920746	526	18.68	264	526	5	275	3.0e-13	70.6	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
643920747	236	40	18	233	1	186	9.0e-51	193	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
643920750	514	31.79	2	431	4	396	4.0e-57	216	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
643920751	349	31.14	2	347	1	329	2.0e-57	216	COG2404	Oligoribonuclease NrnB or cAMP/cGMP phosphodiesterase, DHH superfamily	339
643920752	752	44.97	7	749	2	694	0.0e+00	720	COG1298	Flagellar biosynthesis pathway, component FlhA	696
643920753	91	55.06	1	89	1	89	6.0e-22	95.6	COG0184	Ribosomal protein S15P/S13E	89
643920754	613	32.72	10	610	25	663	2.0e-118	420	COG1200	RecG-like helicase	677
643920755	431	22.89	35	428	28	428	8.0e-48	184	COG0612	Predicted Zn-dependent peptidase	438
643920756	378	43.13	11	378	1	366	9.0e-110	390	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
643920757	746	31.16	10	746	7	766	0.0e+00	485	COG4775	Outer membrane protein assembly factor BamA	766
643920758	275	34.29	1	273	4	277	3.0e-58	218	COG0287	Prephenate dehydrogenase	279
643920759	390	23.35	1	384	5	389	1.0e-24	108	COG0475	Kef-type K+ transport system, membrane component KefB	397
643920762	563	50.63	2	557	1	549	0.0e+00	669	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
643920763	156	40.13	1	154	1	157	4.0e-30	124	COG0440	Acetolactate synthase, small subunit	163
643920764	340	41.04	41	338	25	330	8.0e-82	297	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
643920766	466	37.5	1	462	7	471	3.0e-129	455	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
643920767	756	56.84	424	752	2	328	2.0e-115	410	COG0620	Methionine synthase II (cobalamin-independent)	330
643920768	190	36.05	45	187	35	181	1.0e-24	106	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
643920769	193	32.67	2	193	1	189	2.0e-36	145	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
643920770	144	34.19	3	118	1	117	2.0e-18	84.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
643920775	300	20.78	1	287	1	300	2.0e-19	89.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643920776	187	38.46	1	180	1	173	6.0e-36	143	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
643920777	300	21.25	2	293	1	312	2.0e-23	103	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643920778	362	22.78	9	339	1	313	3.0e-34	139	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643920779	443	27.52	38	440	5	370	4.0e-84	305	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
643920783	377	22.77	3	374	4	382	1.0e-69	257	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
643920784	348	42.94	6	346	2	346	6.0e-105	374	COG2089	Sialic acid synthase SpsE, contains C-terminal SAF domain	347
643920785	446	23.9	14	446	24	519	1.0e-51	197	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
643920786	238	30.83	1	235	4	248	2.0e-37	149	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643920793	663	43.7	5	661	35	671	0.0e+00	684	COG3563	Capsule polysaccharide export protein KpsC/LpsZ	671
643920794	360	42.54	137	359	89	314	2.0e-53	203	COG2829	Outer membrane phospholipase A	317
643920795	254	25.82	1	244	16	253	3.0e-22	99.1	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
643920796	219	37.27	1	219	24	241	2.0e-60	225	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
643920797	375	38.67	1	375	1	372	2.0e-92	332	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
643920798	308	21	63	275	18	233	4.0e-20	92.1	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
643920800	391	40.91	1	389	1	394	1.0e-93	336	COG3562	Capsule polysaccharide modification protein KpsS	403
643920801	335	54.22	2	333	1	323	6.0e-122	430	COG1087	UDP-glucose 4-epimerase	329
643920804	345	23.05	5	345	1	307	2.0e-33	136	COG2124	Cytochrome P450	411
643920812	628	54.91	3	628	6	622	0.0e+00	748	COG0326	Molecular chaperone, HSP90 family	623
643920813	941	55.53	7	939	1	933	0.0e+00	1314	COG0178	Excinuclease UvrABC ATPase subunit	935
643920815	736	28.3	25	736	38	753	2.0e-100	360	COG1193	dsDNA-specific endonuclease/ATPase MutS2	753
643920817	444	36.28	6	441	7	451	1.0e-103	370	COG0773	UDP-N-acetylmuramate-alanine ligase	459
643920819	292	33.33	4	291	8	301	2.0e-51	196	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
643920820	505	39.76	1	481	21	513	1.0e-111	397	COG0513	Superfamily II DNA and RNA helicase	513
643920821	233	26.18	8	227	1	226	4.0e-22	98.1	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
643920823	219	49.12	1	219	3	230	1.0e-79	289	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
643920824	78	52.56	1	78	2	79	7.0e-20	88.7	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
643920825	238	52.54	4	238	2	236	1.0e-79	289	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
643920826	431	40.94	7	401	7	406	3.0e-92	332	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
643920827	639	54.76	2	630	4	621	0.0e+00	862	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
643920830	250	29.41	2	250	1	255	1.0e-14	73.9	COG0730	Uncharacterized membrane protein YfcA	258
643920831	173	31.71	10	164	1	157	9.0e-24	103	COG3663	G:T/U-mismatch repair DNA glycosylase	169
643920833	235	26.36	15	234	4	240	1.0e-36	146	COG1385	16S rRNA U1498 N3-methylase RsmE	246
643920840	596	26.12	218	596	34	407	6.0e-28	119	COG0840	Methyl-accepting chemotaxis protein	408
643920841	312	45.93	24	307	49	354	3.0e-87	315	COG1858	Cytochrome c peroxidase	364
643920842	334	50.76	5	331	2	322	5.0e-107	381	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
643920843	331	49.09	1	323	2	331	6.0e-107	380	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
643920844	50	42	1	49	1	50	4.0e-06	42.9	COG0333	Ribosomal protein L32	57
643920846	137	63.16	1	133	2	134	3.0e-54	203	COG0105	Nucleoside diphosphate kinase	135
643920847	231	32.16	7	231	1	252	1.0e-34	139	COG1427	Predicted periplasmic solute-binding protein	252
643920848	285	22.89	1	281	12	289	8.0e-37	147	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
643920849	198	48.72	1	194	3	194	2.0e-62	232	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
643920850	386	67.1	1	385	1	388	0.0e+00	637	COG0192	S-adenosylmethionine synthetase	388
643920851	357	27.52	1	256	39	272	3.0e-28	119	COG1442	Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase	325
643920863	235	45.11	1	232	2	236	3.0e-72	265	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
643920865	275	35.04	32	274	51	299	1.0e-53	203	COG2264	Ribosomal protein L11 methylase PrmA	300
643920866	643	51.57	26	626	1	592	0.0e+00	628	COG0465	ATP-dependent Zn proteases	596
643920867	200	19.07	1	195	21	233	4.0e-09	54.9	COG0688	Phosphatidylserine decarboxylase	239
643920868	243	45.49	1	231	3	227	4.0e-38	151	COG1183	Phosphatidylserine synthase	234
643920870	447	48.27	8	351	66	407	4.0e-95	342	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
643920871	310	40.14	9	283	1	268	1.0e-59	223	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
643920875	115	38.46	1	77	1	78	7.0e-13	66	COG1314	Preprotein translocase subunit SecG	86
643920876	186	52.15	1	186	2	187	7.0e-56	210	COG0233	Ribosome recycling factor	187
643920877	203	32.69	1	202	5	201	3.0e-38	151	COG0461	Orotate phosphoribosyltransferase	201
643920878	156	25.36	20	152	10	147	2.0e-06	45.5	COG1714	Uncharacterized membrane protein YckC, RDD family	172
643920879	226	35.96	3	219	17	243	5.0e-34	137	COG0356	FoF1-type ATP synthase, membrane subunit a	246
643920880	188	25.88	1	162	2	167	1.0e-16	79.6	COG0352	Thiamine monophosphate synthase	211
643920881	362	56.55	11	362	2	345	1.0e-120	426	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
643920882	161	44.83	1	158	7	178	5.0e-46	176	COG0066	3-isopropylmalate dehydratase small subunit	191
643920886	268	38.3	1	141	1	130	2.0e-30	126	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
643920887	254	28.96	1	253	2	256	8.0e-38	150	COG0725	ABC-type molybdate transport system, periplasmic component	258
643920889	220	44.7	1	217	3	219	2.0e-54	205	COG4149	ABC-type molybdate transport system, permease component	225
643920891	406	29.67	18	406	2	419	4.0e-29	122	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
643920892	242	52.44	4	227	2	226	2.0e-76	278	COG1136	ABC-type lipoprotein export system, ATPase component	226
643920893	431	22.25	18	343	12	352	6.0e-28	118	COG1566	Multidrug resistance efflux pump	352
643920894	476	25.35	45	467	21	444	4.0e-40	159	COG1538	Outer membrane protein TolC	457
643920895	478	42.56	10	478	2	443	0.0e+00	465	COG0174	Glutamine synthetase	443
643920896	254	26.56	1	230	1	235	1.0e-26	113	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
643920897	247	42.69	1	245	1	250	2.0e-46	179	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643920898	77	57.14	1	77	4	80	3.0e-12	63.8	COG0236	Acyl carrier protein	80
643920899	409	52.88	1	409	2	411	3.0e-129	455	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
643920900	308	56.96	1	308	1	316	3.0e-118	418	COG0825	Acetyl-CoA carboxylase alpha subunit	317
643920902	320	35.28	9	315	9	302	2.0e-38	153	COG3301	Formate-dependent nitrite reductase, membrane component NrfD	305
643920903	189	42.47	1	181	8	192	3.0e-42	164	COG0437	Fe-S-cluster-containing dehydrogenase component	203
643920905	593	29.44	5	541	4	545	2.0e-87	317	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
643920909	197	38.37	26	188	2	168	3.0e-34	138	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
643920912	207	35.14	22	203	15	194	5.0e-36	144	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
643920914	285	57.8	2	282	1	282	7.0e-108	383	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
643920915	263	31.67	1	118	1	117	8.0e-11	61.2	COG0681	Signal peptidase I	166
643920916	227	37.02	1	178	7	170	3.0e-06	45.8	COG1994	Zn-dependent protease (includes SpoIVFB)	230
643920917	141	55.24	1	141	1	143	3.0e-46	177	COG0698	Ribose 5-phosphate isomerase RpiB	151
643920919	184	46.89	4	179	1	172	1.0e-39	155	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
643920920	289	30.9	1	270	1	275	1.0e-41	164	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
643920923	119	39.66	1	116	1	116	2.0e-16	77.8	COG1734	RNA polymerase-binding transcription factor DksA	120
643920924	154	37.8	32	154	31	155	3.0e-29	121	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
643920925	284	56.47	3	280	4	281	6.0e-111	393	COG0777	Acetyl-CoA carboxylase beta subunit	294
643920926	252	20.37	7	196	14	223	3.0e-12	65.8	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
643920927	353	36.5	19	353	14	341	3.0e-67	249	COG1566	Multidrug resistance efflux pump	352
643920929	391	41.39	4	388	14	431	0.0e+00	468	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
643920931	188	36.27	1	188	3	180	8.0e-34	136	COG0241	Histidinol phosphatase or a related phosphatase	181
643920932	186	36.22	7	173	22	217	4.0e-18	84.6	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
643920933	85	50.75	3	69	9	75	6.0e-17	79.1	COG0238	Ribosomal protein S18	75
643920934	160	39.76	1	160	2	167	3.0e-34	137	COG0629	Single-stranded DNA-binding protein	167
643920935	142	45.19	2	105	1	104	8.0e-25	106	COG0360	Ribosomal protein S6	112
643920936	333	22.86	1	308	1	308	2.0e-14	73.5	COG1466	DNA polymerase III, delta subunit	334
643920937	716	30.23	17	658	35	687	2.0e-110	393	COG0557	Exoribonuclease R	706
643920938	272	20.8	1	264	12	284	4.0e-25	108	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
643920939	332	25.9	11	330	1	314	2.0e-41	163	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643920940	507	45.69	2	506	10	465	0.0e+00	499	COG2870	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase	467
643920941	189	54.29	1	174	1	175	1.0e-62	232	COG0279	Phosphoheptose isomerase	176
643920943	260	47.41	4	248	4	254	8.0e-59	220	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
643920944	110	36.63	11	110	1	101	2.0e-07	47.5	COG0640	DNA-binding transcriptional regulator, ArsR family	110
643920945	651	32.88	11	651	73	709	0.0e+00	552	COG2217	Cation transport ATPase	713
643920947	139	35.85	2	104	1	106	7.0e-17	79.7	COG2076	Multidrug transporter EmrE and related cation transporters	106
643920948	104	41.35	1	104	2	105	1.0e-14	71.3	COG2076	Multidrug transporter EmrE and related cation transporters	106
643920949	195	36.73	32	177	44	189	2.0e-12	66.2	COG3334	Flagellar motility protein MotE, a chaperone for MotC folding	192
643920953	425	46.85	2	321	1	333	2.0e-95	342	COG0460	Homoserine dehydrogenase	333
643920954	118	22.81	5	115	3	112	7.0e-19	86	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
643920955	155	59.4	10	142	17	149	1.0e-49	188	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
643920956	398	56.5	1	398	5	402	9.0e-118	417	COG0786	Na+/glutamate symporter	404
643920957	428	40.36	2	426	1	442	0.0e+00	491	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
643920959	215	38.24	14	215	4	200	2.0e-34	138	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
643920960	772	59.45	1	567	1	575	0.0e+00	819	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
643920961	355	27.6	1	355	1	364	3.0e-41	162	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
643920962	430	42.96	4	427	4	408	6.0e-105	374	COG0593	Chromosomal replication initiation ATPase DnaA	408
643920963	160	44.37	4	153	1	150	3.0e-43	167	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
643920964	212	39.15	1	203	23	234	2.0e-49	189	COG1351	Thymidylate synthase ThyX	273
643920966	369	45.99	9	194	1	185	9.0e-51	194	COG1636	Predicted ATPase, Adenine nucleotide alpha hydrolases (AANH) superfamily	204
643920968	292	51.2	1	289	55	344	8.0e-95	340	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
643920970	405	58.06	5	405	2	400	0.0e+00	580	COG0137	Argininosuccinate synthase	403
643920971	728	58.19	1	728	6	744	0.0e+00	1063	COG2838	Monomeric isocitrate dehydrogenase	744
643920972	481	42.57	3	445	7	432	2.0e-109	389	COG0305	Replicative DNA helicase	435
643920975	212	24.22	1	211	1	207	1.0e-23	103	COG2830	Uncharacterized protein	214
643920976	390	33.33	1	384	4	387	3.0e-80	292	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
643920977	380	49.34	5	379	2	366	0.0e+00	470	COG0505	Carbamoylphosphate synthase small subunit	368
643920978	183	50.27	1	183	1	183	4.0e-44	170	COG2952	Uncharacterized protein	183
643920979	202	28.24	1	198	3	218	1.0e-35	143	COG0132	Dethiobiotin synthetase	223
643920980	453	45.45	173	447	4	262	2.0e-75	276	COG1760	L-serine deaminase	262
643920990	502	37.98	38	502	12	499	3.0e-114	405	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
643920991	398	27	1	397	1	397	3.0e-50	193	COG1459	Type II secretory pathway, component PulF	397
643920993	375	38.1	124	375	21	267	5.0e-59	221	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
643920994	243	49.57	1	234	5	238	1.0e-78	286	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
643920997	111	27	1	93	1	100	1.0e-07	48.3	COG1539	Dihydroneopterin aldolase	121
643920998	159	58.71	1	155	2	156	1.0e-60	225	COG1225	Peroxiredoxin	157
643921000	329	24.19	11	249	18	259	4.0e-25	109	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
643921003	191	35.32	1	188	1	200	1.0e-38	152	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
643921005	469	34.19	2	462	9	466	4.0e-68	252	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
643921007	307	32.76	1	278	7	289	1.0e-47	183	COG0731	Wyosine [tRNA(Phe)-imidazoG37] synthetase, radical SAM superfamily	296
643921008	180	38.74	1	175	1	191	2.0e-32	132	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
643921012	641	38.87	1	544	1	529	5.0e-130	458	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
643921013	271	40.14	1	270	1	279	5.0e-51	195	COG0682	Prolipoprotein diacylglyceryltransferase	287
643921016	602	39.27	17	583	1	560	0.0e+00	512	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
643921017	325	24.05	9	325	5	344	9.0e-24	104	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643921018	189	45.88	1	189	2	189	4.0e-55	207	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
643921019	298	22.78	118	294	39	215	1.0e-11	63.8	COG1261	Flagella basal body P-ring formation protein FlgA	220
643921020	716	33.88	2	710	1	709	0.0e+00	591	COG2217	Cation transport ATPase	713
643921021	340	41.26	3	340	1	346	7.0e-91	327	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
643921022	240	30.8	9	236	8	256	2.0e-27	116	COG0388	Predicted amidohydrolase	274
643921023	208	41.38	5	206	2	204	1.0e-56	213	COG2518	Protein-L-isoaspartate O-methyltransferase	209
643921024	248	28.73	1	244	1	267	2.0e-46	178	COG0253	Diaminopimelate epimerase	272
643921025	438	35.98	3	433	13	462	3.0e-97	348	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
643921029	424	43.34	5	354	4	346	2.0e-90	326	COG0826	Collagenase-like protease, PrtC family	347
643921031	382	37.14	7	381	11	387	3.0e-66	245	COG2814	Predicted arabinose efflux permease, MFS family	394
643921034	273	20.46	46	271	70	328	3.0e-18	85.7	COG0673	Predicted dehydrogenase	342
643921040	210	36.48	4	162	1	159	4.0e-37	148	COG4185	Predicted ABC-type ATPase	187
643921042	416	28.86	1	393	1	360	1.0e-35	144	COG0675	Transposase	364
643921049	292	23.58	12	232	10	225	3.0e-08	53.1	COG2253	Predicted nucleotidyltransferase component of viral defense system	258
643921051	253	58.33	10	249	2	237	2.0e-104	371	COG1126	ABC-type polar amino acid transport system, ATPase component	240
643921052	217	35.19	3	216	8	218	4.0e-41	161	COG0765	ABC-type amino acid transport system, permease component	222
643921053	222	38.46	1	220	1	221	4.0e-42	164	COG0765	ABC-type amino acid transport system, permease component	222
643921054	142	44.44	1	142	6	149	5.0e-35	140	COG1981	Uncharacterized membrane protein	149
643921055	470	53.17	4	460	3	458	0.0e+00	590	COG0165	Argininosuccinate lyase	459
643921056	239	36.07	1	239	6	238	1.0e-59	223	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
643921057	612	39.61	12	611	2	581	0.0e+00	496	COG0322	Excinuclease UvrABC, nuclease subunit	581
643921060	488	39.96	4	486	9	492	4.0e-128	452	COG0029	Aspartate oxidase	518
643921061	278	30.94	11	276	1	274	1.0e-43	170	COG2301	Citrate lyase beta subunit	283
643921063	1159	29.8	522	961	16	462	6.0e-86	313	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643921064	451	24.6	4	446	8	424	2.0e-41	163	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
643921065	417	19.15	36	410	47	390	1.0e-06	47.9	COG2814	Predicted arabinose efflux permease, MFS family	394
643921066	344	43.93	1	318	1	308	5.0e-78	284	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
643921068	316	36.81	3	303	4	307	2.0e-65	242	COG2958	Uncharacterized protein	307
643921069	727	65.89	429	727	23	315	0.0e+00	509	COG0519	GMP synthase, PP-ATPase domain/subunit	315
643921070	328	40.91	20	328	1	328	2.0e-72	266	COG0270	Site-specific DNA-cytosine methylase	328
643921073	566	22.31	1	338	1	339	2.0e-12	67.7	COG3950	Predicted ATP-binding protein involved in virulence	440
643921074	76	32.39	1	71	1	71	3.0e-08	50.2	COG1918	Fe2+ transport system protein FeoA	75
643921076	519	40.08	11	519	183	652	3.0e-123	435	COG0370	Fe2+ transport system protein B	653
643921079	465	24.32	1	463	2	410	4.0e-30	126	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
643921080	435	18.12	65	383	63	351	6.0e-11	62.5	COG2814	Predicted arabinose efflux permease, MFS family	394
643921081	216	31.31	1	211	9	222	1.0e-32	132	COG1802	DNA-binding transcriptional regulator, GntR family	230
643921084	414	36.43	6	410	7	415	4.0e-57	215	COG0814	Amino acid permease	415
643921087	302	22.37	4	300	3	284	1.0e-22	100	COG0685	5,10-methylenetetrahydrofolate reductase	291
643921088	392	33.68	6	391	13	374	8.0e-52	198	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
643921089	418	47.11	20	393	17	394	2.0e-113	402	COG0019	Diaminopimelate decarboxylase	394
643921090	354	43.37	84	354	1	275	1.0e-73	270	COG0077	Prephenate dehydratase	279
643921091	157	29.68	4	157	1	138	3.0e-12	64.9	COG1580	Flagellar basal body-associated protein FliL	159
643921093	65	32.2	1	59	1	57	1.0e-09	54.9	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
643921094	318	27.24	3	318	2	300	3.0e-32	132	COG0492	Thioredoxin reductase	305
643921095	62	54.84	1	61	1	62	3.0e-10	56.8	COG0227	Ribosomal protein L28	77
643921096	376	26.18	138	369	3	225	7.0e-14	71.8	COG0569	Trk K+ transport system, NAD-binding component	225
643921097	396	43.14	7	396	8	404	4.0e-112	398	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
643921098	74	47.89	1	71	1	71	2.0e-11	60.7	COG2841	Uncharacterized conserved protein YdcH, DUF465 family	72
643921099	108	33.98	1	102	2	104	1.0e-15	74.9	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
643921103	576	35.64	3	576	8	596	6.0e-123	435	COG1164	Oligoendopeptidase F	598
643921104	475	58.71	1	475	3	481	0.0e+00	669	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
643921105	417	42.08	1	414	9	429	9.0e-125	440	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
643921106	568	26.48	5	558	4	539	4.0e-71	262	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
643921107	309	24	8	282	2	266	2.0e-19	89.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
643921108	372	23.51	2	372	1	378	8.0e-22	98.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643921109	380	22.74	1	354	3	348	2.0e-23	103	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643921110	118	61.67	1	118	4	123	5.0e-43	166	COG0853	Aspartate 1-decarboxylase	126
643921111	102	37.5	7	100	10	105	3.0e-15	73.3	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
643921113	288	36.19	1	263	3	261	7.0e-52	197	COG0142	Geranylgeranyl pyrophosphate synthase	322
643921114	260	42.25	3	259	2	252	9.0e-77	280	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
643921115	230	37.74	1	225	8	259	3.0e-57	215	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
643921117	293	33.56	2	291	1	274	7.0e-53	200	COG0388	Predicted amidohydrolase	274
643921119	446	31.18	1	446	4	450	9.0e-52	198	COG0534	Na+-driven multidrug efflux pump	455
643921121	442	51.27	13	441	1	419	0.0e+00	505	COG0172	Seryl-tRNA synthetase	429
643921123	483	32.88	253	471	1	170	8.0e-36	145	COG0516	IMP dehydrogenase/GMP reductase	170
643921124	451	43.31	3	448	9	468	3.0e-124	439	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
643921126	644	16.16	52	644	89	768	7.0e-16	79.6	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643921127	289	34.97	7	288	6	265	6.0e-37	148	COG0428	Zinc transporter ZupT	266
643921128	200	25.32	1	157	3	153	1.0e-15	77	COG3467	Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily	166
643921129	326	41.67	11	154	3	150	1.0e-28	120	COG0822	NifU homolog involved in Fe-S cluster formation	150
643921130	390	54.4	6	390	1	385	0.0e+00	515	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
643921131	246	45.16	1	245	5	243	1.0e-73	269	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
643921132	84	57.95	1	83	2	88	9.0e-21	91.6	COG3809	Predicted nucleic acid-binding protein, contains Zn-finger domain	88
643921134	401	30.56	118	401	3	269	1.0e-59	223	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
643921135	227	31.48	17	222	34	244	2.0e-33	136	COG1496	Copper oxidase (laccase) domain	249
643921136	341	34.62	1	330	1	338	1.0e-60	227	COG1077	Actin-like ATPase involved in cell morphogenesis	342
643921137	404	27.49	127	394	11	294	2.0e-21	96.9	COG0501	Zn-dependent protease with chaperone function	302
643921138	278	34.63	1	278	1	276	1.0e-46	180	COG2890	Methylase of polypeptide chain release factors	280
643921143	497	53.71	1	495	7	502	0.0e+00	639	COG1190	Lysyl-tRNA synthetase (class II)	502
643921144	187	25.97	4	184	1	176	5.0e-14	71	COG1286	Uncharacterized membrane protein, required for colicin V production	182
643921145	167	41.72	4	166	3	163	4.0e-29	121	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
643921146	421	21.6	9	421	16	458	2.0e-41	163	COG0815	Apolipoprotein N-acyltransferase	518
643921148	527	31.42	46	411	1	285	1.0e-37	151	COG0306	Phosphate/sulfate permease	326
643921149	244	32.22	7	241	2	230	8.0e-45	173	COG2063	Flagellar basal body L-ring protein FlgH	230
643921150	486	29.81	5	461	2	409	2.0e-73	270	COG0498	Threonine synthase	411
643921153	216	28.12	2	213	28	250	2.0e-33	135	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
643921154	237	32.77	1	235	2	236	7.0e-33	134	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
643921155	408	33.86	4	367	1	363	6.0e-74	271	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
643921156	265	30.68	23	249	11	272	1.0e-37	150	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
643921157	305	43.45	7	294	4	284	2.0e-71	262	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
643921158	360	22.37	54	345	2	282	1.0e-23	104	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
643921159	229	53.7	1	107	5	110	5.0e-40	157	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
643921161	299	39.13	2	296	5	323	4.0e-78	285	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
643921162	400	55.7	8	400	1	394	0.0e+00	538	COG0133	Tryptophan synthase beta chain	396
643921163	330	50.29	1	328	1	340	3.0e-112	398	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
643921165	262	37.55	1	241	7	263	7.0e-58	217	COG0169	Shikimate 5-dehydrogenase	283
643921166	182	22.22	1	108	1	101	5.0e-09	54.1	COG1544	Ribosome-associated translation inhibitor RaiA	110
643921167	417	28.23	9	376	24	397	6.0e-48	185	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
643921168	425	50.49	23	424	3	402	3.0e-106	379	COG0004	Ammonia channel protein AmtB	409
643921169	115	50.91	6	115	3	112	8.0e-27	112	COG0347	Nitrogen regulatory protein PII	112
643921170	335	29.97	1	304	1	304	9.0e-47	180	COG2603	tRNA 2-selenouridine synthase SelU, contains rhodanese domain	334
643921171	363	65.82	125	359	1	237	1.0e-94	339	COG1186	Protein chain release factor B	239
643921172	170	32.94	1	169	1	151	2.0e-22	98.5	COG0716	Flavodoxin	151
643921173	566	30.68	1	360	17	381	3.0e-43	170	COG0475	Kef-type K+ transport system, membrane component KefB	397
643921176	1047	52.51	13	449	1	421	0.0e+00	561	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
643921177	197	63.08	3	195	1	195	8.0e-85	306	COG0529	Adenylylsulfate kinase or related kinase	197
643921180	258	24.3	5	252	1	251	1.0e-15	77.4	COG0730	Uncharacterized membrane protein YfcA	258
643921182	263	38.02	1	262	89	345	6.0e-54	204	COG0709	Selenophosphate synthase	346
643921185	488	50	1	483	4	501	0.0e+00	607	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
643921186	352	37.21	15	352	1	316	8.0e-48	184	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
643921187	404	31.35	4	404	12	446	8.0e-84	304	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
643921188	299	24.08	1	296	1	292	2.0e-28	119	COG0583	DNA-binding transcriptional regulator, LysR family	297
643921189	370	35.38	8	366	3	334	1.0e-58	220	COG2855	Uncharacterized membrane protein YadS	334
643921190	103	30.95	18	96	10	93	8.0e-08	48.8	COG0607	Rhodanese-related sulfurtransferase	110
643921191	197	26.7	11	197	2	186	2.0e-35	141	COG0742	16S rRNA G966 N2-methylase RsmD	187
643921193	184	43.54	42	184	33	179	2.0e-36	145	COG2032	Cu/Zn superoxide dismutase	179
643921194	162	55.48	1	146	1	146	5.0e-57	213	COG0757	3-dehydroquinate dehydratase	146
643921195	347	32.59	4	345	29	373	5.0e-63	234	COG0006	Xaa-Pro aminopeptidase	384
643921196	198	34.65	70	194	4	128	7.0e-27	113	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
643921199	238	29.06	1	229	31	256	3.0e-36	145	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
643921201	235	33.33	1	231	11	247	7.0e-35	140	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
643921202	352	44.12	1	337	1	332	2.0e-89	322	COG1868	Flagellar motor switch protein FliM	332
643921204	447	52.74	1	447	1	453	0.0e+00	563	COG1066	Predicted ATP-dependent serine protease	456
643921205	295	48.54	1	290	33	340	3.0e-85	308	COG0552	Signal recognition particle GTPase	340
643921212	499	27.61	2	492	8	478	1.0e-52	201	COG0286	Type I restriction-modification system, DNA methylase subunit	489
643921214	303	24.43	2	302	107	391	2.0e-15	76.6	COG0732	Restriction endonuclease S subunit	391
643921221	139	40	2	136	1	123	5.0e-12	63.6	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
643921222	314	54.69	1	307	1	306	7.0e-103	367	COG0181	Porphobilinogen deaminase	307
643921225	442	35.28	1	422	1	414	3.0e-90	326	COG0373	Glutamyl-tRNA reductase	414
643921226	306	32.37	2	303	9	315	2.0e-54	206	COG0142	Geranylgeranyl pyrophosphate synthase	322
643921229	432	48.56	17	432	10	424	0.0e+00	509	COG0141	Histidinol dehydrogenase	425
643921231	181	31.82	1	169	1	175	2.0e-30	125	COG3150	Predicted esterase YcpF, UPF0227 family	191
643921232	164	56.41	1	156	3	158	2.0e-56	211	COG2077	Peroxiredoxin	158
643921233	335	57.43	4	205	3	202	2.0e-81	295	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
643921237	311	45.91	1	311	3	313	2.0e-90	326	COG0275	16S rRNA C1402 N4-methylase RsmH	314
643921238	422	55.79	1	422	1	420	0.0e+00	557	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
643921240	275	56.99	1	271	3	272	2.0e-109	388	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
643921241	258	43.32	7	246	32	273	6.0e-60	224	COG2607	Predicted ATPase, AAA+ superfamily	287
643921242	746	42.91	5	731	3	786	0.0e+00	768	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
643921246	320	39.1	6	317	10	298	8.0e-88	317	COG1242	Radical SAM superfamily enzyme	312
643921247	456	49.23	7	456	2	454	0.0e+00	605	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
643921248	255	44.15	1	255	2	266	2.0e-74	272	COG0289	Dihydrodipicolinate reductase	266
643921249	312	47.44	1	312	3	304	9.0e-81	293	COG0492	Thioredoxin reductase	305
643921252	432	50.58	3	432	9	440	0.0e+00	544	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
643921253	296	41.54	1	294	1	324	2.0e-81	295	COG0240	Glycerol-3-phosphate dehydrogenase	329
643921254	335	43.79	2	333	14	347	8.0e-85	307	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
643921255	430	50.47	7	430	4	425	0.0e+00	530	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
643921256	344	23.81	5	143	29	175	2.0e-06	47	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
643921257	73	43.24	1	73	5	76	7.0e-13	65.7	COG0425	TusA-related sulfurtransferase	78
643921258	296	49.01	1	295	1	302	2.0e-109	389	COG1897	Homoserine trans-succinylase	307
643921261	648	35.99	125	504	1	382	1.0e-67	251	COG0458	Carbamoylphosphate synthase large subunit	400
643921262	441	67.34	13	404	1	393	0.0e+00	534	COG0458	Carbamoylphosphate synthase large subunit	400
643921263	206	49.72	7	185	3	179	1.0e-54	205	COG0194	Guanylate kinase	191
643921267	263	44.4	1	263	1	256	4.0e-74	271	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
643921268	204	45.1	1	196	1	204	9.0e-57	213	COG0307	Riboflavin synthase alpha chain	204
643921269	93	48.84	6	91	7	92	8.0e-22	95.3	COG2257	Type III secretion system substrate exporter, FlhB-like	92
643921270	259	25.48	1	259	1	232	7.0e-24	104	COG1387	Histidinol phosphatase or related hydrolase of the PHP family	237
643921272	304	29.32	2	299	83	379	6.0e-27	114	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643921273	201	51.61	5	185	39	224	2.0e-63	235	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
643921276	359	51.98	3	353	1	354	7.0e-126	443	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
643921277	416	49.64	1	416	3	416	0.0e+00	519	COG0014	Gamma-glutamyl phosphate reductase	417
643921278	698	47.88	11	679	11	694	0.0e+00	795	COG0855	Polyphosphate kinase	696
643921279	223	42.67	3	223	2	224	7.0e-59	220	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
643921280	356	33.78	1	351	3	375	2.0e-47	183	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
643921281	180	36.56	3	179	11	187	1.0e-15	76.2	COG0558	Phosphatidylglycerophosphate synthase	192
643921282	260	29.69	4	256	2	249	5.0e-41	161	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643921283	304	43.54	9	299	7	292	1.0e-78	286	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
643921284	436	32.48	13	434	3	428	4.0e-80	292	COG0612	Predicted Zn-dependent peptidase	438
643921285	351	38.71	51	351	2	308	2.0e-75	275	COG0167	Dihydroorotate dehydrogenase	310
643921288	857	51.51	6	857	1	784	0.0e+00	894	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
643921289	167	49.7	4	166	8	172	2.0e-55	208	COG0225	Peptide methionine sulfoxide reductase MsrA	174
643921291	222	41.48	2	222	1	227	1.0e-57	216	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643921292	412	26.39	136	391	43	308	1.0e-21	98.3	COG0642	Signal transduction histidine kinase	336
643921294	68	43.28	3	68	2	64	1.0e-12	64.9	COG2879	Uncharacterized short protein YbdD, DUF466 family	65
643921295	135	37.5	1	134	7	141	1.0e-25	108	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
643921296	446	48.67	1	444	1	449	0.0e+00	496	COG0541	Signal recognition particle GTPase	451
643921297	75	52	2	75	1	75	2.0e-23	100	COG0228	Ribosomal protein S16	87
643921298	79	31.51	2	74	1	72	1.0e-10	57.9	COG1837	Predicted RNA-binding protein YlqC, contains KH domain, UPF0109 family	76
643921299	183	28.26	6	181	2	174	9.0e-23	99.9	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
643921300	234	45.96	1	234	1	234	1.0e-78	285	COG0336	tRNA G37 N-methylase TrmD	240
643921301	118	58.12	1	117	1	115	1.0e-34	137	COG0335	Ribosomal protein L19	115
643921304	469	42.37	21	372	13	346	5.0e-74	272	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
643921305	498	31.83	5	291	3	290	2.0e-28	120	COG1344	Flagellin and related hook-associated protein FlgL	360
643921306	259	35.32	7	258	18	263	4.0e-55	208	COG0159	Tryptophan synthase alpha chain	265
643921307	422	56.78	10	406	5	393	0.0e+00	537	COG0133	Tryptophan synthase beta chain	396
643921308	490	36.69	20	490	5	461	5.0e-113	401	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
643921309	539	40.7	191	534	1	338	2.0e-95	343	COG0547	Anthranilate phosphoribosyltransferase	338
643921310	495	35.61	6	253	1	252	1.0e-44	174	COG0134	Indole-3-glycerol phosphate synthase	254
643921314	228	36.4	4	226	3	229	3.0e-49	188	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643921315	413	22.97	108	390	18	312	9.0e-20	91.8	COG0642	Signal transduction histidine kinase	336
643921316	321	56.04	1	321	6	327	0.0e+00	480	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
643921317	319	29.77	15	302	14	272	1.0e-44	173	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
643921318	449	46.49	1	449	1	438	0.0e+00	511	COG0015	Adenylosuccinate lyase	438
643921319	229	24.8	5	223	1	249	1.0e-11	63.4	COG0863	DNA modification methylase	302
643921320	135	32.28	1	125	8	132	3.0e-08	51.1	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
643921321	277	37.55	4	271	1	267	3.0e-76	278	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
643921322	346	23.93	30	346	7	295	2.0e-27	116	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
643921324	168	33.09	19	155	1	135	9.0e-21	93.1	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
643921325	485	29.74	161	485	102	441	8.0e-60	224	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
643921326	244	17.97	25	237	21	274	6.0e-15	74.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643921327	345	30	1	309	3	294	1.0e-49	190	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
643921328	358	26.7	1	358	4	359	1.0e-45	177	COG0787	Alanine racemase	360
643921329	104	32.43	1	103	1	102	2.0e-10	57.7	COG2863	Cytochrome c553	121
643921335	410	47.95	2	408	12	408	0.0e+00	468	COG0281	Malic enzyme	432
643921339	274	24.16	1	133	4	151	2.0e-11	63.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
643921341	180	28.11	11	179	13	197	1.0e-20	92.6	COG2928	Uncharacterized membrane protein	222
643921342	284	33.8	1	281	6	289	4.0e-39	155	COG0382	4-hydroxybenzoate polyprenyltransferase	289
643921346	215	40.28	1	208	86	295	4.0e-54	204	COG0083	Homoserine kinase	299
643921348	879	59.65	376	879	1	507	0.0e+00	630	COG0532	Translation initiation factor IF-2, a GTPase	509
643921349	123	24.11	5	116	7	118	9.0e-15	72.5	COG0858	Ribosome-binding factor A	118
643921350	143	40.54	3	143	6	153	6.0e-29	119	COG0779	Ribosome maturation factor RimP	153
643921351	346	32.76	1	173	3	141	1.0e-33	137	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
643921352	353	34.48	1	352	33	409	5.0e-76	278	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
643921354	248	38.56	10	245	1	228	6.0e-66	244	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
643921355	657	43.56	1	585	2	561	0.0e+00	529	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
643921358	81	46.34	1	80	3	84	7.0e-19	85.4	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
643921360	434	37.28	61	434	90	475	4.0e-95	341	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
643921361	212	25.73	12	212	9	212	2.0e-20	92.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643921363	1007	34.78	3	999	6	1087	0.0e+00	643	COG3513	CRISPR/Cas system Type II  associated protein, contains McrA/HNH and RuvC-like nuclease domains	1088
643921364	296	25.64	7	296	4	314	6.0e-39	154	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
643921365	125	51.85	1	108	1	108	6.0e-33	132	COG3512	CRISPR/Cas system-associated protein Cas2, endoribonuclease	116
643921368	189	31.58	24	175	24	174	1.0e-24	106	COG3271	Predicted double-glycine peptidase	201
643921371	146	33.09	8	144	18	156	6.0e-18	83.4	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
643921372	258	63.53	7	258	1	255	2.0e-110	392	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
643921373	335	53.02	8	315	4	313	9.0e-104	370	COG0180	Tryptophanyl-tRNA synthetase	314
643921374	313	36.77	27	312	26	313	2.0e-66	246	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
643921377	229	39.83	1	228	3	233	1.0e-50	193	COG0775	Nucleoside phosphorylase	234
643921378	306	41.29	1	305	2	310	3.0e-74	272	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
643921379	521	34.15	5	521	15	577	6.0e-119	421	COG0018	Arginyl-tRNA synthetase	577
643921380	82	28.77	1	73	2	74	9.0e-11	58.4	COG1826	Sec-independent protein translocase protein TatA	94
643921381	265	39.06	3	234	2	228	5.0e-55	208	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
643921382	243	34.15	6	225	10	255	3.0e-55	208	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
643921383	266	47.49	2	258	23	281	4.0e-62	231	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
643921384	310	46.56	1	309	1	317	7.0e-73	267	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
643921385	501	26.83	14	499	36	551	2.0e-59	223	COG0747	ABC-type transport system, periplasmic component	556
643921386	145	53.79	1	145	1	145	1.0e-50	192	COG1017	Hemoglobin-like flavoprotein	150
643921387	341	65.09	1	338	1	337	0.0e+00	522	COG0059	Ketol-acid reductoisomerase	338
643921389	505	40.08	15	502	1	485	1.0e-129	456	COG0606	Predicted ATPase with chaperone activity	490
643921390	168	43.45	1	167	3	168	2.0e-46	178	COG0242	Peptide deformylase	168
643921391	339	20.28	196	336	12	152	8.0e-06	45.1	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
643921392	196	70.16	3	193	2	192	4.0e-84	304	COG0740	ATP-dependent protease ClpP, protease subunit	200
643921393	434	37.41	4	434	2	425	6.0e-69	255	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
643921394	1125	34.89	473	1123	210	852	2.0e-125	444	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
643921395	357	42.02	2	357	4	360	3.0e-101	361	COG1377	Flagellar biosynthesis protein FlhB	363
643921396	185	24.19	3	180	6	190	3.0e-26	111	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
643921397	321	39.69	1	321	1	322	5.0e-85	307	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
643921398	145	40.28	2	145	14	156	1.0e-32	132	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
643921400	338	39.4	2	336	44	408	7.0e-74	271	COG0232	dGTP triphosphohydrolase	412
643921402	233	25.69	10	218	13	215	2.0e-26	112	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
643921404	396	52.32	12	396	1	379	6.0e-94	337	COG1620	L-lactate permease	522
643921406	480	47.42	6	471	4	459	0.0e+00	548	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
643921407	215	31.22	1	215	2	215	2.0e-33	135	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
643921408	223	45.98	1	223	2	220	3.0e-61	228	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
643921409	127	29.06	9	124	17	129	7.0e-19	86.1	COG2346	Truncated hemoglobin YjbI	133
643921410	146	43.45	1	145	1	145	9.0e-26	109	COG3399	Uncharacterized protein	148
643921412	145	23.84	6	144	62	212	3.0e-16	77.6	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643921414	224	50.22	3	222	18	243	6.0e-72	264	COG0020	Undecaprenyl pyrophosphate synthase	245
643921416	406	36.97	9	406	1	390	2.0e-82	299	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
643921417	605	31.29	1	602	13	599	1.0e-107	384	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
643921419	173	22.86	1	173	1	152	3.0e-16	78.4	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
643921420	209	41.58	7	197	6	195	4.0e-47	181	COG0218	GTP-binding protein EngB required for normal cell division	200
643921421	155	25.37	19	151	33	164	3.0e-14	71.5	COG1934	Lipopolysaccharide export system protein LptA	173
643921423	163	46.63	1	163	7	169	7.0e-49	186	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
643921424	190	51.87	5	190	9	195	2.0e-65	241	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
643921425	267	43.01	26	205	35	215	1.0e-47	183	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
643921428	219	31.88	8	214	1	200	3.0e-47	182	COG2121	Uncharacterized conserved protein, lysophospholipid acyltransferase (LPLAT) superfamily	214
643921439	406	26.17	15	399	1	401	5.0e-55	208	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
643921450	202	52.66	1	202	61	265	4.0e-54	204	COG0548	Acetylglutamate kinase	265
643921452	291	22.38	10	289	8	282	4.0e-09	55.5	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
643921458	122	38.52	1	115	2	123	1.0e-23	101	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
643921461	179	16	17	166	50	222	5.0e-06	44.2	COG0775	Nucleoside phosphorylase	234
643921467	266	39.41	1	266	2	266	8.0e-79	286	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
