gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
647644363	171	48.15	5	166	1	162	8.0e-47	179	COG1329	RNA polymerase-interacting regulator, CarD/CdnL/TRCF family	166
647644364	645	33.78	1	438	4	397	3.0e-55	210	COG0475	Kef-type K+ transport system, membrane component KefB	397
647644365	152	41.45	1	152	4	154	3.0e-30	124	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647644366	364	52.19	4	364	3	362	1.0e-119	423	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
647644368	232	40.34	1	230	9	243	5.0e-34	137	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
647644369	430	58.06	7	428	6	426	0.0e+00	594	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
647644373	264	33.98	7	261	1	254	1.0e-44	173	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
647644375	155	44.93	1	138	2	137	1.0e-41	162	COG1832	Predicted CoA-binding protein	140
647644376	101	54.95	3	93	1	91	4.0e-24	102	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
647644377	253	65.49	1	252	1	255	1.0e-109	389	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
647644378	238	52.94	1	238	2	239	2.0e-81	295	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
647644379	129	41.41	3	129	40	162	1.0e-18	85	COG4731	Uncharacterized conserved protein, DUF2147 family	162
647644380	212	45.75	1	212	2	204	6.0e-66	243	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
647644381	195	62.05	1	195	3	195	4.0e-81	293	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
647644385	557	52.44	18	546	7	515	0.0e+00	547	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
647644387	216	45.79	1	214	9	210	9.0e-72	263	COG0321	Lipoate-protein ligase B	221
647644388	224	43.52	12	224	5	219	8.0e-54	203	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
647644389	551	24.89	15	247	2	219	1.0e-11	65.2	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
647644393	388	27.63	4	282	23	345	1.0e-26	114	COG3673	Uncharacterized protein, PA2063/DUF2235 family	423
647644394	794	18.59	57	735	29	691	2.0e-13	71.3	COG4694	Wobble nucleotide-excising tRNase	758
647644398	347	20.97	22	273	23	256	3.0e-09	56.3	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
647644401	604	28.98	43	595	27	556	8.0e-79	288	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
647644407	557	35.67	20	548	10	547	9.0e-119	420	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
647644408	139	35.59	19	135	6	123	2.0e-17	81.8	COG0818	Diacylglycerol kinase	123
647644409	218	41.23	1	218	1	227	6.0e-48	183	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647644410	452	25.82	150	450	33	333	9.0e-25	108	COG0642	Signal transduction histidine kinase	336
647644411	382	42.24	6	381	5	393	5.0e-99	354	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
647644412	434	49.54	1	434	1	438	0.0e+00	525	COG0015	Adenylosuccinate lyase	438
647644415	344	28.78	9	343	6	337	2.0e-32	133	COG1536	Flagellar motor switch protein FliG	339
647644416	300	29.82	19	296	15	297	8.0e-43	167	COG1560	Lauroyl/myristoyl acyltransferase	308
647644417	232	38.3	7	232	24	256	3.0e-48	185	COG5429	Uncharacterized protein	261
647644418	924	59.72	8	922	1	861	0.0e+00	1180	COG1048	Aconitase A	861
647644419	594	27.04	20	594	33	594	8.0e-72	265	COG0729	Outer membrane translocation and assembly module TamA	594
647644420	1384	19.81	7	1384	17	1278	3.0e-82	301	COG2911	Autotransporter translocation and assembly factor TamB	1278
647644421	172	36.91	17	160	8	156	2.0e-29	122	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
647644422	637	42.83	57	620	2	528	0.0e+00	650	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
647644423	338	24.4	8	333	13	332	5.0e-27	115	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647644424	211	21.2	16	199	2	177	5.0e-09	54.9	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647644425	466	30.33	70	466	5	379	4.0e-55	209	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647644426	484	44.59	13	479	3	465	3.0e-123	435	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647644427	622	24.34	2	622	1	608	6.0e-61	229	COG4206	Outer membrane cobalamin receptor protein	608
647644428	327	43.77	1	324	4	331	4.0e-45	175	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
647644429	252	39.27	3	242	2	248	1.0e-60	226	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
647644430	194	32.29	5	184	12	202	1.0e-18	86.6	COG0811	Biopolymer transport protein ExbB/TolQ	216
647644431	125	28.07	15	124	18	131	3.0e-09	54.5	COG0848	Biopolymer transport protein ExbD	137
647644433	284	24.88	87	284	44	243	1.0e-07	50.9	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
647644435	118	39.25	12	117	1	102	3.0e-17	80.5	COG0633	Ferredoxin	102
647644437	421	54.12	1	421	1	424	0.0e+00	535	COG0151	Phosphoribosylamine-glycine ligase	428
647644438	491	43.97	12	471	2	431	1.0e-122	433	COG1570	Exonuclease VII, large subunit	440
647644440	569	40.9	185	569	16	416	3.0e-110	393	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
647644441	399	52.48	120	395	59	340	2.0e-92	332	COG0552	Signal recognition particle GTPase	340
647644443	199	34.92	12	199	2	177	7.0e-27	113	COG2917	Intracellular septation protein A	180
647644445	234	29.09	4	218	1	210	8.0e-32	130	COG0625	Glutathione S-transferase	211
647644447	406	41.56	12	405	1	395	3.0e-109	389	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
647644448	374	29.29	82	348	4	277	6.0e-47	181	COG1469	GTP cyclohydrolase FolE2	289
647644450	533	30.29	10	525	4	526	8.0e-91	328	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
647644452	312	65.99	8	304	4	288	0.0e+00	505	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
647644454	742	39.81	1	742	3	691	0.0e+00	715	COG0751	Glycyl-tRNA synthetase, beta subunit	691
647644455	841	23.95	17	836	20	740	2.0e-110	393	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
647644457	307	27.97	26	140	3	120	2.0e-11	63.7	COG1539	Dihydroneopterin aldolase	121
647644458	338	46.62	71	335	7	267	7.0e-69	254	COG0294	Dihydropteroate synthase	274
647644459	448	47.26	1	442	6	457	1.0e-118	420	COG1109	Phosphomannomutase	464
647644460	333	26.87	33	326	5	292	3.0e-07	49.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
647644461	397	62.72	58	395	3	338	0.0e+00	523	COG0059	Ketol-acid reductoisomerase	338
647644462	125	28.8	1	125	31	154	4.0e-14	70.1	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647644463	153	39.22	1	153	3	154	2.0e-23	101	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647644464	385	27.12	35	384	29	364	8.0e-57	214	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
647644465	400	31.58	3	397	1	385	2.0e-52	199	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647644466	253	35.11	29	250	3	227	2.0e-28	119	COG1802	DNA-binding transcriptional regulator, GntR family	230
647644467	608	22.47	178	577	4	402	7.0e-36	145	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
647644468	386	51.72	9	385	2	366	0.0e+00	518	COG0505	Carbamoylphosphate synthase small subunit	368
647644469	152	50.66	1	152	1	148	9.0e-34	136	COG1610	Uncharacterized conserved protein YqeY	148
647644470	160	26.71	18	160	20	161	1.0e-11	63	COG5488	Uncharacterized membrane protein	164
647644471	1146	60.93	4	1146	7	1148	0.0e+00	1716	COG1038	Pyruvate carboxylase	1149
647644472	394	35.33	10	375	1	346	2.0e-70	259	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
647644473	806	42.67	29	695	1	649	0.0e+00	623	COG0210	Superfamily I DNA or RNA helicase	655
647644476	356	42.73	104	326	50	265	3.0e-51	196	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
647644477	530	46.69	21	530	7	502	0.0e+00	480	COG1292	Choline-glycine betaine transporter	537
647644478	140	28.7	12	119	27	133	1.0e-13	69.1	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
647644479	330	46.5	7	310	2	314	6.0e-95	341	COG0275	16S rRNA C1402 N4-methylase RsmH	314
647644480	114	23.53	2	96	5	106	3.0e-06	43.9	COG5462	Predicted secreted (periplasmic) protein	138
647644481	471	33.26	51	455	159	596	2.0e-81	296	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
647644482	493	40.79	21	488	8	475	1.0e-106	380	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
647644483	478	40.85	3	468	2	451	4.0e-102	365	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
647644484	360	43.68	19	360	1	316	4.0e-56	212	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
647644485	303	49.35	1	303	3	309	5.0e-105	374	COG2066	Glutaminase	309
647644486	464	39.57	3	461	1	444	2.0e-104	373	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
647644487	404	46.68	13	402	2	404	2.0e-124	439	COG2081	Predicted flavoprotein YhiN	408
647644488	389	33.33	16	375	5	373	5.0e-60	225	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
647644489	366	37.95	6	362	3	357	2.0e-73	269	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
647644490	471	49.03	6	465	2	459	0.0e+00	550	COG0773	UDP-N-acetylmuramate-alanine ligase	459
647644493	316	42.81	21	315	2	288	2.0e-80	292	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
647644494	292	40.19	1	289	9	317	2.0e-71	262	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
647644495	295	27.54	81	285	58	263	3.0e-15	75.8	COG1589	Cell division septal protein FtsQ	269
647644496	434	33.03	7	434	1	418	8.0e-89	320	COG0849	Cell division ATPase FtsA	418
647644497	535	56.06	7	336	10	338	4.0e-107	381	COG0206	Cell division GTPase FtsZ	338
647644498	311	46.67	6	288	4	286	4.0e-87	315	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
647644499	289	35	8	267	1	253	3.0e-57	215	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
647644500	553	43.14	1	547	1	552	0.0e+00	516	COG0497	DNA repair ATPase RecN	557
647644501	561	31.07	40	465	19	441	4.0e-53	202	COG0038	H+/Cl- antiporter ClcA	443
647644503	115	39.45	5	112	19	127	7.0e-27	112	COG2343	Uncharacterized conserved protein, DUF427 family	132
647644504	576	26.84	130	502	1	365	4.0e-49	189	COG0006	Xaa-Pro aminopeptidase	384
647644505	625	52.69	1	608	11	618	0.0e+00	593	COG4547	Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib...	620
647644507	328	18.41	20	325	1	302	3.0e-37	149	COG0714	MoxR-like ATPase	329
647644509	85	55.84	5	81	6	79	3.0e-15	73.5	COG0271	Stress-induced morphogen (activity unknown)	90
647644511	144	25.98	1	126	12	137	5.0e-19	86.9	COG0824	Acyl-CoA thioesterase FadM	137
647644513	369	53.51	2	368	122	481	0.0e+00	499	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
647644517	244	40.64	1	244	4	250	3.0e-36	145	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647644518	850	34.21	1	839	4	855	0.0e+00	556	COG0308	Aminopeptidase N	859
647644520	51	62.79	1	43	1	43	1.0e-08	51.3	COG4338	Uncharacterized protein	54
647644521	717	44.84	246	716	104	545	0.0e+00	485	COG2225	Malate synthase	545
647644522	131	41.41	2	129	17	141	2.0e-17	81.9	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
647644523	258	37.05	1	248	1	243	2.0e-54	205	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
647644524	275	36.92	26	273	1	249	1.0e-39	157	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647644525	535	52.85	13	381	1	356	2.0e-110	393	COG3288	NAD/NADP transhydrogenase alpha subunit	356
647644526	479	53.17	1	478	1	463	0.0e+00	546	COG1282	NAD/NADP transhydrogenase beta subunit	463
647644527	473	30.28	18	440	11	433	3.0e-53	203	COG0534	Na+-driven multidrug efflux pump	455
647644528	427	35.85	3	425	7	417	3.0e-71	262	COG4949	Uncharacterized membrane-anchored protein	424
647644530	332	39.61	27	332	4	289	2.0e-64	239	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647644531	355	36.9	1	354	1	315	2.0e-75	276	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647644534	566	25.35	3	564	18	555	4.0e-62	232	COG0747	ABC-type transport system, periplasmic component	556
647644535	610	53.31	7	565	2	539	0.0e+00	688	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
647644536	382	29.32	1	381	13	406	4.0e-55	208	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647644537	447	30.77	21	439	5	385	2.0e-48	186	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647644538	389	47.58	1	385	2	389	1.0e-113	403	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
647644539	387	47.31	1	382	2	387	6.0e-120	424	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
647644541	428	39.72	5	424	3	416	1.0e-97	350	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
647644542	349	45.21	18	349	1	322	8.0e-102	363	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
647644544	217	23.71	6	199	14	187	2.0e-10	59.2	COG4912	3-methyladenine DNA glycosylase AlkD	222
647644546	606	53.87	1	606	1	597	0.0e+00	758	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
647644547	450	49.67	1	435	1	456	0.0e+00	523	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
647644548	223	35.02	1	216	4	217	2.0e-33	136	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
647644549	396	27.76	10	396	9	374	3.0e-49	189	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
647644550	156	25.6	13	133	14	138	4.0e-14	70.7	COG3871	General stress protein 26 (function unknown)	145
647644551	387	42.97	6	387	1	391	9.0e-93	334	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647644552	162	31.19	51	159	28	121	3.0e-07	48.1	COG3755	Uncharacterized conserved protein YecT, DUF1311 family	127
647644553	507	31.88	14	505	2	524	5.0e-102	364	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
647644554	534	45.15	11	534	1	526	0.0e+00	622	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
647644555	140	32.82	11	136	10	140	4.0e-21	93.9	COG4405	Uncharacterized protein YhfF	140
647644556	649	54.45	1	642	1	645	0.0e+00	743	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
647644557	217	26.7	1	201	1	204	1.0e-23	102	COG0625	Glutathione S-transferase	211
647644559	260	38.61	1	258	3	257	1.0e-38	153	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647644560	299	24.38	1	294	1	301	2.0e-30	126	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647644561	121	54.55	1	121	1	121	1.0e-31	128	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
647644562	178	68.71	16	178	6	168	1.0e-76	278	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
647644563	201	48.88	1	177	2	176	1.0e-45	176	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
647644565	408	58.63	15	408	9	398	0.0e+00	592	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
647644566	421	44.79	11	173	1	160	6.0e-51	195	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
647644567	260	47.11	140	260	19	133	8.0e-21	94.4	COG3743	 Predicted 5' DNA nuclease, flap endonuclease-1-like, helix-3-turn-helix (H3TH) domain	133
647644569	431	59.34	1	421	5	424	0.0e+00	670	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
647644573	671	45.74	6	663	3	684	0.0e+00	644	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
647644575	345	51.04	2	333	1	331	6.0e-92	330	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
647644576	164	45.62	10	164	7	161	4.0e-45	174	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
647644577	133	28.69	14	133	5	124	7.0e-08	49.6	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
647644578	200	45.56	1	169	3	166	6.0e-24	104	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
647644580	101	66.34	1	101	1	100	7.0e-24	102	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
647644581	718	49	3	495	2	474	2.0e-125	443	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
647644582	518	51.37	1	509	1	493	0.0e+00	505	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
647644583	481	45.49	3	479	2	474	2.0e-90	326	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
647644584	215	34.86	6	215	24	235	8.0e-35	140	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
647644585	257	41.9	1	253	1	251	3.0e-62	232	COG1521	Pantothenate kinase type III	251
647644586	555	35.8	9	551	12	554	4.0e-114	405	COG0595	mRNA degradation ribonuclease J1/J2	555
647644587	533	37.03	1	501	28	513	5.0e-112	398	COG0513	Superfamily II DNA and RNA helicase	513
647644589	547	52.27	18	544	4	527	0.0e+00	713	COG4108	Peptide chain release factor RF-3	528
647644592	259	32.82	3	255	1	251	2.0e-30	126	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647644593	446	20.54	36	445	41	487	2.0e-08	54.5	COG0591	Na+/proline symporter	493
647644594	361	38.46	5	360	3	352	2.0e-93	336	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
647644600	206	34.78	1	92	1	92	2.0e-09	55.7	COG1826	Sec-independent protein translocase protein TatA	94
647644601	291	39.25	5	269	1	250	4.0e-61	228	COG0805	Sec-independent protein secretion pathway component TatC	255
647644602	279	56.57	7	279	14	285	2.0e-104	372	COG2607	Predicted ATPase, AAA+ superfamily	287
647644603	412	22.26	181	412	1	265	1.0e-12	67.9	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
647644604	219	49.5	20	218	10	208	7.0e-58	217	COG2518	Protein-L-isoaspartate O-methyltransferase	209
647644605	261	36.4	1	261	1	252	1.0e-65	243	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
647644606	216	27.5	3	197	7	203	6.0e-18	84.5	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647644609	494	52.78	21	482	1	458	0.0e+00	606	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
647644611	455	54.7	1	451	1	456	0.0e+00	591	COG1066	Predicted ATP-dependent serine protease	456
647644614	234	43.28	1	230	8	245	2.0e-68	252	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
647644615	254	42.91	1	254	12	265	1.0e-48	186	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
647644616	376	42.34	32	375	1	359	9.0e-89	320	COG0787	Alanine racemase	360
647644619	498	39.27	20	485	3	433	6.0e-124	438	COG0305	Replicative DNA helicase	435
647644620	226	33.65	11	216	1	200	7.0e-41	160	COG0461	Orotate phosphoribosyltransferase	201
647644621	346	62.21	1	344	1	344	0.0e+00	522	COG0418	Dihydroorotase	344
647644623	293	29.06	19	272	11	250	6.0e-35	141	COG0714	MoxR-like ATPase	329
647644624	417	44.47	9	403	6	392	2.0e-83	303	COG3552	Uncharacterized conserved protein, contains von Willebrand factor type A (vWA) domain	395
647644625	719	47.81	6	712	14	743	0.0e+00	827	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
647644626	301	31.68	1	294	1	297	7.0e-39	154	COG0583	DNA-binding transcriptional regulator, LysR family	297
647644627	1138	29.77	19	691	4	633	0.0e+00	521	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
647644628	295	18.42	57	283	57	278	8.0e-18	84.6	COG3176	Putative hemolysin	292
647644630	342	44.86	1	342	1	349	1.0e-98	353	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
647644631	136	43.85	2	129	12	141	2.0e-31	128	COG2332	Cytochrome c-type biogenesis protein CcmE	153
647644635	150	48.03	1	150	4	152	6.0e-39	153	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
647644636	258	38.28	1	253	2	256	9.0e-50	190	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647644638	431	52.35	28	431	1	390	0.0e+00	490	COG0372	Citrate synthase	390
647644639	466	38.87	1	466	6	471	1.0e-117	417	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
647644640	680	27.35	124	482	106	443	9.0e-28	119	COG0658	Predicted membrane metal-binding protein	453
647644641	239	38.63	7	239	2	200	1.0e-50	192	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
647644642	390	46.46	1	390	6	401	4.0e-95	341	COG0303	Molybdopterin biosynthesis enzyme	404
647644643	270	51.36	6	262	1	254	4.0e-79	287	COG0134	Indole-3-glycerol phosphate synthase	254
647644644	222	45.58	9	219	11	223	2.0e-66	245	COG0692	Uracil DNA glycosylase	223
647644645	339	49.56	1	338	4	338	2.0e-101	362	COG0547	Anthranilate phosphoribosyltransferase	338
647644646	193	57.98	1	187	3	189	2.0e-74	271	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
647644648	469	25.96	246	463	19	244	1.0e-07	51.8	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
647644649	346	32.52	40	316	40	325	2.0e-45	176	COG3608	Predicted deacylase	331
647644650	503	46.76	21	497	1	460	0.0e+00	476	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
647644652	375	24.65	14	359	26	373	1.0e-55	210	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
647644653	170	33.33	15	159	6	149	4.0e-17	81.2	COG2236	Hypoxanthine phosphoribosyltransferase	192
647644654	268	66.54	5	261	3	259	1.0e-114	406	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
647644655	201	48.26	2	201	16	214	1.0e-60	225	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
647644656	182	33.85	12	76	3	67	2.0e-12	65.2	COG1278	Cold shock protein, CspA family	67
647644657	101	40.62	1	96	32	126	7.0e-24	101	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
647644661	269	32.64	25	263	1	239	9.0e-36	143	COG1414	DNA-binding transcriptional regulator, IclR family	246
647644662	526	42.94	2	495	6	486	3.0e-110	392	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
647644663	523	25.09	1	517	18	547	4.0e-62	232	COG0747	ABC-type transport system, periplasmic component	556
647644664	313	45.71	1	313	1	315	3.0e-85	308	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647644665	295	45.99	10	293	3	289	6.0e-62	231	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647644666	562	51.02	11	540	2	535	0.0e+00	621	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
647644667	388	46.7	1	388	2	392	4.0e-117	415	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
647644668	394	25.06	27	394	13	408	1.0e-29	124	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647644669	272	49.22	1	257	3	258	2.0e-87	315	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
647644670	302	32.54	4	297	12	291	2.0e-52	199	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
647644671	294	37.01	30	283	34	281	3.0e-46	178	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
647644672	432	34.27	147	426	7	283	3.0e-52	199	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
647644673	204	25.99	3	174	15	190	8.0e-19	87.3	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
647644674	237	35.78	3	234	4	234	3.0e-46	178	COG2188	DNA-binding transcriptional regulator, GntR family	236
647644675	148	54.11	6	148	6	151	1.0e-39	155	COG3624	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG	151
647644676	186	45.36	1	185	1	194	2.0e-39	155	COG3625	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH	196
647644677	362	63.99	1	359	1	360	0.0e+00	511	COG3626	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI	367
647644678	289	72.5	1	279	9	288	0.0e+00	479	COG3627	Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase	291
647644679	256	75.59	3	256	5	258	4.0e-116	410	COG4107	ABC-type phosphonate transport system, ATPase component	258
647644680	227	61.47	1	227	4	234	6.0e-86	310	COG4778	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL	235
647644681	180	46.59	3	175	5	180	1.0e-39	156	COG3709	Ribose 1,5-bisphosphokinase PhnN	192
647644682	381	47.76	5	381	1	377	2.0e-112	398	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
647644686	529	40.26	5	528	5	538	0.0e+00	463	COG0405	Gamma-glutamyltranspeptidase	539
647644687	337	42.81	38	333	11	315	4.0e-82	298	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
647644688	324	45.06	9	324	1	316	1.0e-102	366	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
647644689	299	46.13	29	297	18	288	1.0e-60	226	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647644690	316	44.03	1	316	1	317	1.0e-79	289	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647644691	534	30.09	13	522	2	541	5.0e-77	282	COG0747	ABC-type transport system, periplasmic component	556
647644692	213	33.96	4	213	16	227	3.0e-25	108	COG1802	DNA-binding transcriptional regulator, GntR family	230
647644697	531	37.45	28	530	8	524	4.0e-113	402	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647644698	217	21.24	19	211	10	193	3.0e-10	58.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647644699	383	21.78	2	319	4	306	1.0e-21	97.7	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647644700	176	23.45	1	143	10	151	1.0e-06	46	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
647644701	436	32.38	54	435	2	379	1.0e-55	211	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647644702	593	35.82	2	593	18	617	2.0e-89	323	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
647644703	318	27.44	9	314	10	321	1.0e-35	143	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
647644704	802	57.29	28	796	2	779	0.0e+00	938	COG2183	Transcriptional accessory protein Tex/SPT6	780
647644705	161	25.89	42	153	12	123	1.0e-09	55.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
647644706	130	31.97	1	122	1	122	5.0e-25	106	COG3232	5-carboxymethyl-2-hydroxymuconate isomerase	127
647644707	501	44.92	25	494	3	472	0.0e+00	494	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647644708	326	23.08	147	267	1	138	6.0e-06	45.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
647644709	465	24.89	14	463	1	449	1.0e-77	284	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
647644710	284	36.5	12	284	2	265	2.0e-57	216	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
647644711	266	50	1	266	2	262	3.0e-65	241	COG3971	2-keto-4-pentenoate hydratase	264
647644712	338	33.14	5	336	2	342	1.0e-54	206	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
647644713	513	49.7	5	502	1	501	0.0e+00	577	COG3845	ABC-type uncharacterized transport system, ATPase component	501
647644714	349	38.4	1	348	1	349	7.0e-66	244	COG4603	ABC-type uncharacterized transport system, permease component	356
647644715	314	41.1	5	313	3	304	2.0e-65	242	COG1079	ABC-type uncharacterized transport system, permease component	304
647644716	426	30.93	1	423	7	421	1.0e-60	227	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
647644717	229	31.3	8	216	25	254	2.0e-25	109	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
647644718	453	31.96	45	453	1	438	2.0e-61	229	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
647644719	512	36.8	8	506	20	514	0.0e+00	514	COG5598	Trimethylamine:corrinoid methyltransferase	526
647644721	390	32.63	22	389	19	393	7.0e-80	291	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
647644722	481	45.28	3	466	1	461	0.0e+00	547	COG0215	Cysteinyl-tRNA synthetase	464
647644723	538	34.65	4	432	1	409	6.0e-91	328	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
647644724	255	22.53	4	229	7	258	3.0e-12	65.8	COG1562	Phytoene/squalene synthetase	288
647644726	245	27.94	7	242	5	251	4.0e-24	104	COG2099	Precorrin-6x reductase	257
647644727	210	39.11	5	208	57	281	2.0e-36	145	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
647644728	221	27.27	1	220	1	207	7.0e-28	117	COG0400	Predicted esterase	207
647644729	194	37.41	33	176	1	146	2.0e-21	95.4	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
647644730	260	46.42	1	260	1	261	3.0e-84	304	COG0708	Exonuclease III	261
647644733	107	44.04	1	106	1	109	2.0e-27	114	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
647644734	362	43.01	2	362	25	410	4.0e-96	345	COG0232	dGTP triphosphohydrolase	412
647644735	580	39.67	1	579	1	577	0.0e+00	522	COG0018	Arginyl-tRNA synthetase	577
647644737	334	36.22	4	309	6	312	2.0e-55	209	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
647644738	264	35.1	20	262	2	242	2.0e-36	146	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
647644739	201	42.94	1	173	6	181	6.0e-38	150	COG1386	Chromosome segregation and condensation protein ScpB	184
647644741	359	26.82	178	356	19	181	2.0e-27	116	COG0717	Deoxycytidine triphosphate deaminase	183
647644744	110	42.86	15	105	1	91	2.0e-26	110	COG0776	Bacterial nucleoid DNA-binding protein	94
647644745	323	54.15	4	323	3	322	1.0e-107	383	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
647644746	358	44.74	17	348	4	332	7.0e-97	347	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
647644747	68	51.79	1	56	1	56	1.0e-16	78	COG0333	Ribosomal protein L32	57
647644749	154	29.58	8	143	6	146	1.0e-10	59.6	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
647644750	231	25.1	2	231	41	284	2.0e-12	66.1	COG3176	Putative hemolysin	292
647644751	603	37.38	5	504	2	530	1.0e-129	457	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
647644752	416	46.36	6	415	2	400	2.0e-122	433	COG0162	Tyrosyl-tRNA synthetase	401
647644753	356	37.43	1	348	11	367	2.0e-70	259	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
647644755	425	68.47	1	425	1	422	0.0e+00	654	COG0148	Enolase	423
647644757	347	27.71	14	341	12	343	2.0e-30	126	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
647644758	437	46.15	1	424	28	453	3.0e-116	412	COG0513	Superfamily II DNA and RNA helicase	513
647644760	414	21.57	17	407	14	394	5.0e-17	82.6	COG2814	Predicted arabinose efflux permease, MFS family	394
647644761	124	32.35	2	101	5	105	3.0e-12	64.1	COG0615	Glycerol-3-phosphate cytidylyltransferase, cytidylyltransferase family	140
647644762	213	45.28	4	213	5	216	1.0e-55	209	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
647644763	504	30.53	14	502	8	527	4.0e-77	282	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647644764	207	25.42	26	142	1	118	6.0e-08	51.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
647644765	221	28.71	5	196	3	211	2.0e-25	109	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
647644766	158	36.43	1	135	3	139	2.0e-26	111	COG0394	Protein-tyrosine-phosphatase	139
647644767	572	26.9	3	571	37	559	1.0e-69	258	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
647644769	247	40.47	18	232	3	205	3.0e-52	198	COG2928	Uncharacterized membrane protein	222
647644770	306	59.26	3	299	10	306	1.0e-103	370	COG2313	Pseudouridine-5'-phosphate glycosidase (pseudoU degradation)	310
647644771	300	26.71	12	295	1	289	8.0e-24	104	COG0524	Sugar or nucleoside kinase, ribokinase family	311
647644774	206	27.45	7	206	6	207	3.0e-21	95.4	COG0352	Thiamine monophosphate synthase	211
647644775	257	40	18	252	5	234	4.0e-57	214	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
647644776	373	34.86	24	370	3	323	3.0e-42	165	COG1612	Heme A synthase	323
647644777	491	41.38	1	486	4	496	0.0e+00	480	COG2317	Zn-dependent carboxypeptidase, M32 family	497
647644780	764	55.62	26	744	11	690	0.0e+00	882	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
647644783	489	50.51	5	486	2	482	0.0e+00	612	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
647644784	223	32.74	1	221	1	226	7.0e-37	147	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
647644785	529	46.27	38	517	3	445	0.0e+00	492	COG0166	Glucose-6-phosphate isomerase	446
647644786	418	32.94	1	408	3	402	1.0e-43	170	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
647644788	133	26.27	4	120	11	128	3.0e-14	70.7	COG0824	Acyl-CoA thioesterase FadM	137
647644789	541	32.41	1	534	2	525	3.0e-111	396	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647644790	345	36.94	20	327	12	314	8.0e-73	267	COG0042	tRNA-dihydrouridine synthase	323
647644791	273	27.84	6	273	2	257	8.0e-11	61.2	COG0730	Uncharacterized membrane protein YfcA	258
647644793	79	35.29	11	78	6	72	4.0e-09	53.1	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
647644794	161	47.1	16	152	1	138	1.0e-36	145	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
647644795	408	28.14	1	295	1	271	5.0e-28	118	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
647644796	444	26.14	59	434	1	387	1.0e-50	194	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647644798	109	51.76	1	83	1	84	3.0e-25	106	COG4311	Sarcosine oxidase delta subunit	97
647644799	1005	37.82	613	1005	2	379	5.0e-94	339	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
647644800	191	27.34	44	182	50	186	1.0e-16	80	COG4583	Sarcosine oxidase gamma subunit	189
647644801	199	50.99	1	198	2	197	8.0e-64	236	COG0605	Superoxide dismutase	204
647644802	183	34.78	1	180	12	194	4.0e-34	137	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
647644804	623	61.57	121	616	1	497	0.0e+00	661	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
647644805	402	22.85	28	397	34	394	5.0e-17	82.2	COG2814	Predicted arabinose efflux permease, MFS family	394
647644806	1269	24.23	3	934	1	811	2.0e-107	384	COG0841	Multidrug efflux pump subunit AcrB	1009
647644808	243	31.22	11	210	4	207	8.0e-19	87.4	COG4649	Uncharacterized protein	221
647644809	467	19.94	107	423	37	357	9.0e-17	81.8	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
647644810	491	42.46	1	471	2	444	0.0e+00	513	COG1160	Predicted GTPases	444
647644812	430	50	1	426	1	428	0.0e+00	510	COG0172	Seryl-tRNA synthetase	429
647644813	493	36.98	255	438	40	230	1.0e-20	94.9	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
647644814	92	45.65	1	92	6	96	1.0e-20	91.4	COG1862	Preprotein translocase subunit YajC	97
647644816	322	42.12	4	314	1	302	3.0e-76	278	COG0341	Preprotein translocase subunit SecF	305
647644818	117	39.02	1	116	5	127	6.0e-20	89.6	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
647644819	205	40.93	1	179	1	193	5.0e-43	167	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
647644820	218	51.15	1	217	4	220	1.0e-35	143	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
647644821	244	37.17	6	231	41	265	1.0e-26	113	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
647644823	172	28.87	56	148	30	126	5.0e-09	54.1	COG0526	Thiol-disulfide isomerase or thioredoxin	127
647644827	468	44	1	468	1	443	0.0e+00	489	COG0174	Glutamine synthetase	443
647644828	112	75	1	112	1	112	1.0e-38	151	COG0347	Nitrogen regulatory protein PII	112
647644831	258	22.49	25	208	40	232	3.0e-17	82.2	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
647644835	349	61.54	6	341	1	337	3.0e-128	451	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
647644836	198	48.4	3	189	1	187	6.0e-64	236	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
647644837	385	42.39	4	369	1	361	2.0e-86	312	COG0349	Ribonuclease D	361
647644839	136	51.11	3	136	9	143	8.0e-39	152	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
647644841	232	47.53	4	225	5	227	9.0e-63	233	COG5012	Methanogenic corrinoid protein MtbC1	227
647644843	359	42.86	40	333	1	289	4.0e-76	278	COG1533	DNA repair photolyase	297
647644846	624	20.79	134	597	35	528	1.0e-21	98.8	COG2898	Lysylphosphatidylglycerol synthetase, C-terminal domain, DUF2156 family	538
647644847	105	60.38	1	103	1	104	6.0e-22	95.5	COG5467	Uncharacterized protein	104
647644848	255	50.83	3	241	1	237	7.0e-81	293	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
647644849	76	54.43	1	76	2	80	1.0e-21	94.5	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
647644850	222	52.23	1	215	3	226	5.0e-80	290	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
647644851	413	28.25	1	404	1	436	2.0e-51	196	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
647644853	444	37.72	1	443	1	461	2.0e-103	370	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
647644856	922	46.7	217	624	77	485	4.0e-108	386	COG1530	Ribonuclease G or E	487
647644857	75	40.79	1	75	2	77	5.0e-17	79.1	COG0425	TusA-related sulfurtransferase	78
647644858	254	46.33	16	232	10	220	5.0e-27	115	COG0785	Cytochrome c biogenesis protein CcdA	220
647644862	297	41.95	5	297	7	325	1.0e-67	250	COG3588	Fructose-bisphosphate aldolase class 1	332
647644865	464	65.58	2	463	1	462	0.0e+00	755	COG0114	Fumarate hydratase class II	462
647644866	144	44.22	2	144	13	156	4.0e-36	143	COG3814	Uncharacterized protein	157
647644867	408	42.51	1	165	10	176	9.0e-26	111	COG2059	Chromate transport protein ChrA	195
647644868	251	33.47	6	245	1	239	2.0e-26	113	COG2186	DNA-binding transcriptional regulator, FadR family	241
647644869	262	27.31	15	258	24	283	3.0e-22	99.3	COG5486	Predicted metal-binding membrane protein	283
647644870	235	35.47	35	233	7	206	7.0e-43	167	COG5588	Uncharacterized protein	207
647644871	160	25.62	1	160	10	166	5.0e-21	93.9	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
647644872	330	33.13	7	328	4	326	9.0e-52	197	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647644873	423	28.71	17	423	1	403	5.0e-60	225	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
647644874	465	40.81	1	461	6	458	6.0e-110	391	COG0415	Deoxyribodipyrimidine photolyase	461
647644875	402	45.8	115	400	3	283	6.0e-82	297	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
647644878	344	48.08	3	312	1	300	3.0e-96	345	COG0031	Cysteine synthase	300
647644879	815	26.71	7	787	25	834	3.0e-92	333	COG3264	Small-conductance mechanosensitive channel	835
647644880	239	43.93	1	234	1	231	3.0e-61	228	COG2872	Ser-tRNA(Ala) deacylase AlaX (editing enzyme)	241
647644886	461	31.25	14	157	14	151	3.0e-20	93.6	COG3666	Transposase	161
647644887	313	20.48	65	313	6	236	1.0e-11	64.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647644890	512	28.62	8	275	7	257	9.0e-19	88.6	COG4584	Transposase	278
647644891	263	37.29	13	244	13	247	4.0e-40	158	COG1484	DNA replication protein DnaC	254
647644897	211	33.65	1	210	2	209	4.0e-31	128	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
647644898	103	30.11	11	103	17	109	1.0e-11	61.4	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
647644900	570	34.36	1	540	1	544	1.0e-125	443	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
647644901	543	26.03	39	490	18	482	2.0e-87	316	COG0069	Glutamate synthase domain 2	485
647644902	242	33.2	15	235	9	255	3.0e-30	125	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
647644903	477	32.74	41	477	1	438	6.0e-65	242	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
647644904	262	28.15	1	261	7	251	9.0e-28	117	COG0121	Predicted glutamine amidotransferase	252
647644905	465	28.79	127	453	8	328	6.0e-33	135	COG0642	Signal transduction histidine kinase	336
647644906	225	46.29	1	224	1	228	2.0e-60	225	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647644907	187	28.21	27	182	25	178	1.0e-07	49.8	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
647644908	216	43.53	44	210	1	170	6.0e-41	160	COG4420	Uncharacterized membrane protein	191
647644909	853	45.72	318	853	1	537	0.0e+00	477	COG2898	Lysylphosphatidylglycerol synthetase, C-terminal domain, DUF2156 family	538
647644910	107	27.37	8	98	19	113	2.0e-06	44.1	COG2149	Uncharacterized membrane protein YidH, DUF202 family	120
647644914	334	40.79	1	328	12	341	2.0e-68	252	COG1566	Multidrug resistance efflux pump	352
647644915	174	50.61	1	164	3	166	1.0e-51	195	COG4803	Uncharacterized membrane protein	170
647644917	260	33.08	1	257	1	250	6.0e-41	161	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647644919	248	73.58	1	246	1	246	4.0e-112	397	COG4689	Acetoacetate decarboxylase	247
647644920	367	24.78	8	349	13	306	1.0e-34	140	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
647644922	315	26.71	20	292	40	311	3.0e-28	119	COG0668	Small-conductance mechanosensitive channel	316
647644928	383	36.68	13	380	1	349	2.0e-70	259	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
647644929	247	37.5	5	246	3	251	1.0e-37	149	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647644930	254	43.14	5	252	1	251	1.0e-44	173	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647644931	427	25.63	37	423	7	383	4.0e-40	159	COG0006	Xaa-Pro aminopeptidase	384
647644932	269	32.21	5	266	2	250	3.0e-41	162	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647644933	616	25.75	219	611	47	430	2.0e-28	121	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
647644936	255	33.46	2	252	11	250	3.0e-38	152	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647644937	324	39.37	6	316	1	311	9.0e-49	187	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
647644938	333	34.85	23	329	15	315	2.0e-47	183	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
647644939	421	52.29	1	369	2	372	0.0e+00	476	COG1129	ABC-type sugar transport system, ATPase component	500
647644941	287	43.17	10	284	1	265	3.0e-68	252	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
647644942	323	48.6	1	320	5	325	1.0e-101	363	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
647644943	456	62.61	1	443	2	443	0.0e+00	661	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
647644945	292	42.32	1	292	5	290	5.0e-68	251	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
647644946	213	53.44	4	192	2	187	7.0e-65	240	COG0194	Guanylate kinase	191
647644947	173	51.45	1	173	2	174	2.0e-61	228	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
647644948	350	31.71	4	346	110	450	3.0e-47	182	COG5002	Signal transduction histidine kinase	459
647644949	359	22.92	1	341	6	315	4.0e-37	149	COG0226	ABC-type phosphate transport system, periplasmic component	318
647644950	508	43.32	203	507	11	310	2.0e-68	253	COG0573	ABC-type phosphate transport system, permease component	310
647644951	443	38.75	175	443	30	292	2.0e-62	233	COG0581	ABC-type phosphate transport system, permease component	292
647644952	270	66.54	17	270	2	253	2.0e-126	445	COG1117	ABC-type phosphate transport system, ATPase component	253
647644953	235	44.05	4	230	7	233	1.0e-43	170	COG0704	Phosphate uptake regulator	240
647644954	229	51.54	6	228	1	225	7.0e-61	227	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647644955	279	44.24	12	275	3	263	4.0e-73	267	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
647644956	336	39.88	1	325	1	311	1.0e-71	263	COG2826	Transposase and inactivated derivatives, IS30 family	318
647644958	133	25.66	16	127	1	107	7.0e-14	69.6	COG0607	Rhodanese-related sulfurtransferase	110
647644959	143	62.24	2	142	1	143	2.0e-55	208	COG0757	3-dehydroquinate dehydratase	146
647644960	291	52.33	1	291	2	296	6.0e-86	311	COG0264	Translation elongation factor EF-Ts	296
647644961	261	55.36	1	224	27	250	6.0e-87	314	COG0052	Ribosomal protein S2	252
647644964	277	27.62	27	228	2	203	2.0e-19	89.6	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
647644965	254	35.71	9	254	38	288	2.0e-38	152	COG3176	Putative hemolysin	292
647644967	198	31.84	4	197	10	209	1.0e-22	99.7	COG5385	Uncharacterized protein	214
647644968	425	54.46	13	425	3	417	0.0e+00	546	COG0014	Gamma-glutamyl phosphate reductase	417
647644969	369	54.47	4	368	3	368	5.0e-117	414	COG0263	Glutamate 5-kinase	369
647644970	344	60	1	339	1	345	0.0e+00	469	COG0536	GTPase involved in cell partioning and DNA repair	369
647644971	180	29.48	14	178	5	177	4.0e-18	84.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
647644972	200	25.6	1	199	2	208	2.0e-12	65.7	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
647644973	201	26.59	14	179	10	182	1.0e-19	90	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
647644974	89	64.37	1	87	1	87	7.0e-31	125	COG0211	Ribosomal protein L27	87
647644975	267	53.85	34	136	1	103	4.0e-27	115	COG0261	Ribosomal protein L21	103
647644980	233	45.11	2	231	1	235	2.0e-71	261	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
647644981	248	46.18	1	245	2	250	1.0e-69	256	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
647644982	311	36.18	1	297	3	304	5.0e-34	138	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
647644983	308	34.5	1	308	1	296	3.0e-36	145	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
647644984	389	31.49	17	367	1	360	6.0e-46	178	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
647644985	417	25.75	1	361	3	344	3.0e-37	149	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647644987	279	18.45	45	250	55	287	3.0e-11	62.6	COG0657	Acetyl esterase/lipase	312
647644989	341	33.61	223	341	10	126	1.0e-17	84.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647644990	358	38.89	29	358	63	397	1.0e-68	253	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
647644991	397	27.69	18	334	2	322	5.0e-27	115	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
647644992	259	42.4	1	250	4	250	3.0e-75	275	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
647644994	278	49.34	55	278	12	237	7.0e-78	283	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
647644996	336	31.27	14	336	9	295	1.0e-37	151	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
647644997	434	34.78	159	434	80	308	4.0e-24	106	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
647644998	535	27.98	41	467	6	465	2.0e-34	140	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
647644999	218	26.95	47	212	13	176	5.0e-15	74.6	COG5342	Invasion protein IalB, involved in pathogenesis	181
647645000	402	43.1	1	402	2	411	7.0e-107	381	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
647645001	85	34.94	1	82	4	80	2.0e-06	44.1	COG0236	Acyl carrier protein	80
647645002	361	37.46	1	355	2	337	3.0e-68	252	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
647645003	516	35.59	34	498	86	544	1.0e-90	327	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
647645005	181	39.23	2	181	7	184	1.0e-34	139	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
647645006	184	47.18	42	182	18	158	3.0e-28	118	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
647645011	140	58.96	2	135	1	134	3.0e-52	197	COG0105	Nucleoside diphosphate kinase	135
647645012	620	43.83	1	515	3	525	0.0e+00	507	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
647645013	218	43.63	8	211	6	199	2.0e-37	148	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
647645014	194	33.17	5	192	16	213	2.0e-32	131	COG3577	Predicted aspartyl protease	215
647645015	153	32.21	1	149	1	144	2.0e-21	95.4	COG2927	DNA polymerase III, chi subunit	144
647645016	484	42.95	18	482	15	485	3.0e-119	422	COG0260	Leucyl aminopeptidase	485
647645017	376	23.55	1	357	1	356	1.0e-33	137	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
647645018	365	26.9	1	365	2	364	3.0e-35	142	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
647645019	714	23.98	24	711	51	775	7.0e-67	249	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
647645020	411	17.78	11	274	2	270	5.0e-07	49.3	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
647645021	327	51.23	10	327	4	328	8.0e-99	353	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
647645022	280	44.87	19	280	2	257	6.0e-72	264	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
647645024	271	39.41	1	265	7	272	2.0e-53	202	COG2890	Methylase of polypeptide chain release factors	280
647645025	371	60.56	21	371	3	362	0.0e+00	497	COG0216	Protein chain release factor A	363
647645027	321	39.74	21	315	2	301	6.0e-61	227	COG0010	Arginase family enzyme	305
647645028	321	37.54	28	314	3	301	8.0e-59	221	COG0010	Arginase family enzyme	305
647645029	389	47.3	1	383	2	388	3.0e-116	412	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
647645031	313	56.73	2	313	1	310	4.0e-115	408	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
647645033	470	44.63	7	470	10	488	0.0e+00	520	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
647645034	297	26.48	10	293	7	290	3.0e-06	46	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
647645035	273	28.11	62	268	5	220	3.0e-16	78.9	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
647645036	1174	44.33	19	1164	12	1139	0.0e+00	1268	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
647645038	332	56.79	8	330	5	327	0.0e+00	466	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
647645040	293	49.82	8	292	1	285	9.0e-87	313	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
647645041	814	30.57	1	796	2	756	2.0e-98	353	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
647645043	133	40.77	1	130	1	128	3.0e-17	80.7	COG4852	Uncharacterized membrane protein	134
647645044	412	44.78	11	412	14	409	2.0e-102	366	COG2262	50S ribosomal subunit-associated GTPase HflX	411
647645045	79	64.38	6	78	5	77	5.0e-28	115	COG1923	sRNA-binding regulator protein Hfq	77
647645046	511	26.91	23	510	16	487	5.0e-30	126	COG0168	Trk-type K+ transport system, membrane component	499
647645047	471	32.76	14	244	1	225	9.0e-39	155	COG0569	Trk K+ transport system, NAD-binding component	225
647645049	470	44.08	1	449	4	456	0.0e+00	468	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
647645050	740	38.98	7	727	1	709	0.0e+00	544	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
647645051	455	34.37	1	454	3	464	5.0e-97	348	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
647645052	371	38.2	8	359	11	362	1.0e-76	280	COG3852	Signal transduction histidine kinase, nitrogen specific	363
647645053	328	41.53	7	316	6	315	7.0e-79	287	COG0042	tRNA-dihydrouridine synthase	323
647645054	379	55.77	223	378	1	156	2.0e-57	216	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
647645055	163	36.73	7	150	20	154	3.0e-18	85	COG1267	Phosphatidylglycerophosphatase A	160
647645056	157	54.9	6	157	10	161	3.0e-40	157	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
647645057	393	50	1	391	1	404	1.0e-103	370	COG0004	Ammonia channel protein AmtB	409
647645058	427	23.96	1	409	3	430	1.0e-40	160	COG2079	2-methylcitrate dehydratase PrpD	453
647645059	151	47.3	1	148	1	144	4.0e-42	163	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
647645060	179	53.98	1	176	1	175	2.0e-61	228	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
647645062	317	59	10	309	9	306	0.0e+00	461	COG0320	Lipoate synthase	306
647645063	546	20.41	7	347	3	289	7.0e-20	92.3	COG0492	Thioredoxin reductase	305
647645066	520	69.28	202	520	1	315	0.0e+00	546	COG0519	GMP synthase, PP-ATPase domain/subunit	315
647645068	287	21.79	2	274	8	276	6.0e-06	45.3	COG5006	Threonine/homoserine efflux transporter RhtA	292
647645070	305	49.83	1	302	1	303	1.0e-124	439	COG1897	Homoserine trans-succinylase	307
647645071	320	27.24	37	317	4	282	1.0e-18	87.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647645072	289	53.31	12	268	17	269	6.0e-89	320	COG2326	Polyphosphate kinase 2, PPK2 family	270
647645073	205	24.12	1	199	3	201	3.0e-10	58.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647645074	334	25.38	8	319	2	325	4.0e-39	155	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
647645075	162	60.47	34	162	2	130	6.0e-46	176	COG0103	Ribosomal protein S9	130
647645076	153	56.08	1	147	1	148	3.0e-53	200	COG0102	Ribosomal protein L13	148
647645077	473	28.51	12	464	1	453	1.0e-67	251	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
647645079	136	34.51	24	136	28	139	1.0e-17	82.4	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
647645080	261	35.25	1	259	4	257	1.0e-46	179	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647645081	460	58.11	11	453	2	435	0.0e+00	629	COG1206	Folate-dependent tRNA-U54 methylase TrmFO/GidA	439
647645083	119	58.42	8	107	11	111	3.0e-40	157	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
647645084	153	24.11	10	149	6	146	2.0e-20	92	COG0822	NifU homolog involved in Fe-S cluster formation	150
647645086	696	49.4	6	668	3	664	0.0e+00	780	COG1200	RecG-like helicase	677
647645087	706	52.65	9	703	1	666	0.0e+00	871	COG0272	NAD-dependent DNA ligase	667
647645088	239	39.13	1	225	1	229	2.0e-53	202	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647645090	383	40.1	1	381	2	377	6.0e-101	361	COG0763	Lipid A disaccharide synthetase	381
647645091	263	38.87	2	255	7	271	4.0e-48	185	COG3494	Uncharacterized conserved protein, DUF1009 family	279
647645092	260	46.3	1	256	3	259	4.0e-83	301	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
647645093	152	48.98	5	150	1	144	9.0e-41	159	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
647645094	187	23.12	11	181	4	170	2.0e-08	52.7	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
647645095	749	33.29	2	749	14	766	0.0e+00	501	COG4775	Outer membrane protein assembly factor BamA	766
647645097	450	29.68	14	448	2	371	2.0e-38	153	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
647645098	390	45.27	1	390	1	385	3.0e-124	438	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
647645099	244	28.85	1	237	12	264	4.0e-26	111	COG0575	CDP-diglyceride synthetase	265
647645100	246	55.32	10	244	11	245	5.0e-86	310	COG0020	Undecaprenyl pyrophosphate synthase	245
647645101	187	48.6	10	187	9	187	8.0e-56	210	COG0233	Ribosome recycling factor	187
647645102	242	59.49	7	242	2	238	2.0e-86	312	COG0528	Uridylate kinase	238
647645103	296	40.22	22	285	6	280	3.0e-68	252	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
647645104	267	26.05	140	258	1	119	5.0e-13	68.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647645106	361	30.28	1	360	1	315	2.0e-57	216	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647645108	696	47.99	10	330	1	315	2.0e-104	373	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
647645110	165	40.24	2	165	7	167	2.0e-32	132	COG0629	Single-stranded DNA-binding protein	167
647645111	371	49.86	3	365	2	356	2.0e-116	412	COG0337	3-dehydroquinate synthetase	360
647645112	198	39.76	21	186	2	166	5.0e-49	187	COG0703	Shikimate kinase	172
647645115	324	44.52	1	308	1	300	6.0e-83	300	COG4974	Site-specific recombinase XerD	300
647645116	435	46.34	13	435	3	416	4.0e-130	458	COG4536	Mg2+ and Co2+ transporter CorB, contains DUF21, CBS pair, and CorC-HlyC domains	423
647645117	806	33.58	414	806	1	379	4.0e-83	303	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
647645118	446	24.94	27	426	40	448	1.0e-50	194	COG4325	Uncharacterized membrane protein	464
647645120	802	33.67	414	802	1	379	3.0e-84	307	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
647645121	204	31.98	1	196	1	192	2.0e-24	105	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
647645122	618	30.15	15	420	74	477	3.0e-07	50.7	COG2931	Ca2+-binding protein, RTX toxin-related	510
647645126	848	31.66	486	798	69	406	1.0e-37	152	COG0840	Methyl-accepting chemotaxis protein	408
647645128	172	32.87	2	144	22	161	4.0e-16	77.6	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
647645129	155	36.08	1	154	10	167	7.0e-15	73.5	COG1495	Disulfide bond formation protein DsbB	170
647645130	114	24.77	2	107	40	148	2.0e-08	51.2	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647645131	294	35.79	7	289	38	305	1.0e-48	187	COG0010	Arginase family enzyme	305
647645132	349	41.21	12	332	4	330	3.0e-84	305	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
647645133	395	28.53	12	377	4	373	4.0e-42	165	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647645134	144	52.5	24	143	1	120	3.0e-26	111	COG1734	RNA polymerase-binding transcription factor DksA	120
647645135	279	25.45	1	264	18	278	7.0e-36	144	COG0714	MoxR-like ATPase	329
647645138	395	63.13	1	395	1	392	0.0e+00	537	COG3825	Uncharacterized conserved protein,  contains von Willebrand factor type A (vWA) domain	393
647645141	408	36.13	21	408	2	392	2.0e-80	292	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
647645144	934	33.96	18	879	29	932	0.0e+00	608	COG1391	Glutamine synthetase adenylyltransferase	963
647645147	261	49.79	2	234	15	251	3.0e-74	271	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
647645150	362	38.4	1	343	1	349	8.0e-82	297	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
647645151	473	46.31	16	460	5	450	1.0e-121	430	COG4564	Signal transduction histidine kinase	459
647645152	218	41.71	10	213	1	211	1.0e-51	196	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
647645153	583	50.27	4	564	1	549	0.0e+00	647	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
647645154	200	55.97	42	200	4	160	2.0e-48	185	COG0440	Acetolactate synthase, small subunit	163
647645157	382	26.6	17	382	1	363	1.0e-37	150	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
647645158	465	35.73	1	462	7	475	1.0e-99	357	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
647645160	374	61.44	126	360	1	236	9.0e-94	337	COG1186	Protein chain release factor B	239
647645161	850	43.45	1	797	1	765	0.0e+00	814	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
647645162	404	33.62	158	391	27	227	2.0e-40	160	COG0860	N-acetylmuramoyl-L-alanine amidase	231
647645163	380	32.31	7	380	4	392	6.0e-79	288	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
647645164	252	29.46	1	252	1	244	7.0e-30	124	COG1651	Protein-disulfide isomerase	244
647645167	384	22.53	6	366	1	316	4.0e-38	152	COG0270	Site-specific DNA-cytosine methylase	328
647645168	373	57.06	12	372	1	361	0.0e+00	506	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
647645169	413	22.15	27	341	4	279	2.0e-15	77.1	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
647645170	407	43.72	1	395	1	388	1.0e-112	400	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
647645172	266	22.35	1	246	6	256	3.0e-09	55.9	COG4727	Uncharacterized protein	287
647645174	458	23.59	3	458	1	407	2.0e-53	203	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647645180	121	46.07	6	93	2	90	5.0e-18	83	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
647645181	89	39.77	1	88	2	89	8.0e-09	52	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
647645182	163	38.36	5	163	1	158	6.0e-34	136	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
647645183	548	33.2	1	508	1	502	2.0e-62	233	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
647645184	123	46.88	1	93	3	98	8.0e-19	86	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
647645185	965	42.99	3	520	1	511	4.0e-113	403	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
647645186	251	49.28	36	243	3	203	1.0e-59	223	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
647645189	314	21	33	299	17	283	2.0e-24	106	COG0685	5,10-methylenetetrahydrofolate reductase	291
647645191	166	35.65	55	166	18	130	8.0e-21	93.4	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
647645193	406	51.24	1	399	2	400	0.0e+00	464	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
647645196	427	26.94	25	421	14	410	1.0e-51	197	COG0719	Fe-S cluster assembly scaffold protein SufB	412
647645197	251	61.35	1	251	3	248	1.0e-98	352	COG0396	Fe-S cluster assembly ATPase SufC	251
647645199	104	47.62	1	103	1	105	1.0e-23	101	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
647645201	504	41.43	46	502	1	412	3.0e-122	432	COG0719	Fe-S cluster assembly scaffold protein SufB	412
647645202	358	36.22	1	354	1	379	3.0e-78	285	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
647645203	153	38.13	1	139	1	137	4.0e-30	123	COG1959	DNA-binding transcriptional regulator, IscR family	150
647645204	217	58.77	1	211	4	207	2.0e-73	269	COG2945	Alpha/beta superfamily hydrolase	210
647645206	193	26.53	8	145	5	145	8.0e-13	66.9	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
647645207	404	32.86	1	398	14	406	2.0e-123	435	COG0538	Isocitrate dehydrogenase	407
647645210	152	42.48	1	152	3	154	7.0e-31	126	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647645211	109	49.04	1	104	2	105	3.0e-20	90.1	COG2076	Multidrug transporter EmrE and related cation transporters	106
647645212	606	60.23	1	606	3	603	0.0e+00	920	COG1217	Predicted membrane GTPase involved in stress response	603
647645214	95	47.31	1	92	2	94	2.0e-19	87.2	COG5470	Uncharacterized conserved protein, DUF1330 family	96
647645215	885	51.62	1	885	5	877	0.0e+00	1125	COG0013	Alanyl-tRNA synthetase	879
647645216	356	62.37	11	294	1	279	9.0e-86	310	COG0468	RecA/RadA recombinase	279
647645218	386	35.38	116	362	53	311	1.0e-50	193	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
647645220	446	25	93	444	21	388	4.0e-27	116	COG1680	CubicO group peptidase, beta-lactamase class C family	390
647645221	426	33.57	158	426	26	302	8.0e-41	161	COG0668	Small-conductance mechanosensitive channel	316
647645222	296	37.5	179	290	8	119	5.0e-19	88.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647645223	289	30.99	2	242	7	229	1.0e-33	136	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647645224	270	38.63	2	231	7	227	6.0e-46	177	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647645225	301	33.44	2	301	5	309	3.0e-34	138	COG0679	Predicted permease	311
647645226	316	28.83	34	310	14	294	3.0e-33	135	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
647645227	568	34.92	312	562	94	336	2.0e-36	148	COG0642	Signal transduction histidine kinase	336
647645228	451	30.54	239	440	15	170	3.0e-32	133	COG0516	IMP dehydrogenase/GMP reductase	170
647645229	321	35.92	13	310	1	299	1.0e-51	196	COG0010	Arginase family enzyme	305
647645230	701	39.76	24	700	1	612	0.0e+00	548	COG3894	Uncharacterized 2Fe-2 and 4Fe-4S clusters-containing protein, contains DUF4445 domain	614
647645236	264	35.05	164	259	24	120	4.0e-15	75.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647645237	118	30.77	17	107	27	116	1.0e-13	68.5	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
647645240	144	44.44	17	140	1	126	8.0e-44	169	COG0229	Peptide methionine sulfoxide reductase MsrB	140
647645241	189	43.92	1	189	7	182	1.0e-33	135	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
647645244	654	35.56	380	648	99	335	5.0e-42	166	COG0642	Signal transduction histidine kinase	336
647645246	335	32.91	8	318	1	298	3.0e-64	239	COG1162	Putative ribosome biogenesis GTPase RsgA	301
647645247	451	33.24	17	391	6	364	1.0e-92	333	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
647645248	244	29.8	26	220	12	207	2.0e-28	119	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
647645249	135	30.41	1	135	4	151	3.0e-07	47.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
647645250	535	69.94	53	531	1	478	0.0e+00	701	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
647645251	241	63.91	6	235	2	224	3.0e-97	347	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
647645252	64	37.04	3	54	2	55	4.0e-07	46.4	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
647645253	289	26.42	62	217	3	150	3.0e-15	76.2	COG2010	Cytochrome c, mono- and diheme variants	150
647645254	412	34.28	22	338	58	353	4.0e-61	229	COG0348	Polyferredoxin	386
647645255	716	37.57	30	713	6	708	0.0e+00	513	COG2217	Cation transport ATPase	713
647645256	58	51.72	1	57	1	58	7.0e-12	62.2	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
647645257	268	35.66	19	259	12	253	2.0e-42	166	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647645261	802	63.87	7	777	8	782	0.0e+00	1140	COG0466	ATP-dependent Lon protease, bacterial type	782
647645262	365	42.13	1	363	2	362	1.0e-97	349	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
647645263	375	56.28	6	371	1	366	0.0e+00	517	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
647645264	297	34.02	13	294	2	290	2.0e-33	136	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
647645268	460	30.25	160	451	4	316	2.0e-54	206	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
647645269	121	48.48	23	120	12	110	1.0e-27	114	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
647645270	411	20.85	73	403	9	251	6.0e-10	59.1	COG0584	Glycerophosphoryl diester phosphodiesterase	257
647645271	115	45.28	8	111	2	107	3.0e-33	133	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
647645272	266	49.6	18	266	1	250	4.0e-74	271	COG0149	Triosephosphate isomerase	251
647645273	458	43.11	52	450	5	378	1.0e-91	330	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647645274	226	26.44	11	218	8	174	4.0e-21	95	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647645275	333	38.32	1	332	1	332	3.0e-88	318	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647645276	409	37.5	1	409	3	463	4.0e-85	308	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
647645277	604	36.1	16	597	1	602	1.0e-98	354	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
647645278	393	37.91	8	392	25	408	3.0e-67	249	COG2124	Cytochrome P450	411
647645279	153	38.96	1	153	2	154	2.0e-27	115	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647645280	298	38.14	1	193	1	194	1.0e-35	143	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
647645283	554	37.97	1	544	1	509	3.0e-130	459	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
647645284	261	40.08	16	254	3	247	3.0e-52	198	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
647645285	133	30.15	1	110	3	138	1.0e-11	62.2	COG3749	Uncharacterized conserved protein, DUF934 family	167
647645286	282	28.04	23	280	9	266	3.0e-35	142	COG1018	Ferredoxin-NADP reductase	266
647645288	228	60.36	56	224	4	172	5.0e-67	247	COG0290	Translation initiation factor IF-3	176
647645290	263	33.81	1	263	1	280	2.0e-49	189	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
647645291	787	39.08	7	787	6	731	0.0e+00	603	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
647645293	161	56.21	1	153	1	153	1.0e-56	212	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
647645294	327	24.36	1	326	2	346	2.0e-22	99	COG0303	Molybdopterin biosynthesis enzyme	404
647645295	322	37.62	10	320	6	258	5.0e-46	178	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
647645296	102	36.36	25	102	1	85	5.0e-13	66.1	COG0271	Stress-induced morphogen (activity unknown)	90
647645298	120	54.29	1	104	1	105	4.0e-38	149	COG0278	Glutaredoxin-related protein	105
647645301	130	29.76	1	84	1	84	1.0e-06	45.3	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
647645304	671	52.4	17	671	10	662	0.0e+00	850	COG0021	Transketolase	663
647645306	329	49.5	2	304	4	292	8.0e-75	274	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
647645307	333	53.45	2	331	1	332	1.0e-113	403	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
647645309	333	57.96	2	331	1	332	7.0e-123	433	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
647645310	164	51.53	1	163	2	159	5.0e-53	200	COG0669	Phosphopantetheine adenylyltransferase	159
647645312	298	26.94	4	290	2	294	2.0e-25	110	COG0583	DNA-binding transcriptional regulator, LysR family	297
647645313	499	37.47	6	486	3	472	9.0e-119	420	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647645314	393	40.87	14	391	1	388	7.0e-86	310	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647645315	347	24.21	1	317	4	257	3.0e-31	129	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647645316	293	43.34	5	288	2	286	3.0e-67	248	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
647645317	960	67.09	5	954	4	935	0.0e+00	1555	COG0178	Excinuclease UvrABC ATPase subunit	935
647645319	464	46.7	3	453	2	453	0.0e+00	473	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
647645320	194	46.33	4	180	9	182	1.0e-45	175	COG3803	Uncharacterized conserved protein, DUF924 family	182
647645321	405	18.82	33	362	54	393	2.0e-06	47.5	COG2814	Predicted arabinose efflux permease, MFS family	394
647645322	358	51.69	5	354	1	346	7.0e-125	440	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
647645324	153	56.86	1	153	3	155	6.0e-56	209	COG1225	Peroxiredoxin	157
647645325	268	43.98	1	266	3	264	6.0e-67	247	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
647645326	436	34.11	174	426	5	258	3.0e-37	149	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
647645327	170	29.52	47	149	22	126	3.0e-16	78.4	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
647645328	184	37.65	27	184	3	158	1.0e-36	146	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
647645329	168	38.55	10	166	1	158	2.0e-38	151	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
647645330	397	48.49	4	395	5	390	1.0e-122	433	COG0126	3-phosphoglycerate kinase	395
647645332	336	51.52	3	329	15	343	4.0e-116	411	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
647645333	456	53.54	133	456	1	324	0.0e+00	474	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
647645334	435	44.04	1	434	1	402	4.0e-101	361	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
647645335	278	51.87	92	278	5	191	3.0e-63	235	COG1045	Serine acetyltransferase	194
647645339	210	49.19	26	210	1	184	6.0e-52	197	COG5448	Uncharacterized protein	184
647645342	146	45.93	1	135	1	135	3.0e-36	144	COG5437	Predicted secreted protein	138
647645346	315	41.88	2	315	104	421	7.0e-72	264	COG4653	Predicted phage phi-C31 gp36 major capsid-like protein	422
647645348	202	33.54	31	180	16	173	1.0e-23	103	COG3740	Phage head maturation protease	194
647645350	392	40.62	5	386	3	381	1.0e-81	297	COG4695	Phage portal protein BeeE	398
647645351	452	53.9	16	438	6	399	6.0e-108	384	COG5323	Large terminase phage packaging protein	410
647645352	394	36.07	7	380	9	342	2.0e-78	286	COG1559	Cell division protein YceG, involved in septum cleavage	342
647645353	405	54.93	2	404	17	411	5.0e-128	451	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
647645354	160	27.03	1	143	15	159	2.0e-11	62.3	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
647645355	77	60	1	75	3	77	2.0e-12	64.2	COG0236	Acyl carrier protein	80
647645356	245	48.82	2	243	1	251	9.0e-50	190	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647645357	310	51.61	1	310	2	310	3.0e-87	315	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
647645358	402	35.33	3	186	1	179	3.0e-32	133	COG3038	Cytochrome b561	181
647645359	191	43.75	1	191	1	192	2.0e-37	149	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
647645361	120	44.55	4	113	3	112	9.0e-25	105	COG0360	Ribosomal protein S6	112
647645362	75	70.15	4	70	9	75	8.0e-20	88.7	COG0238	Ribosomal protein S18	75
647645363	206	45.58	1	147	1	147	8.0e-42	163	COG0359	Ribosomal protein L9	148
647645365	444	39.33	1	438	1	441	6.0e-80	291	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
647645366	94	55.41	21	94	11	84	3.0e-16	76.9	COG3750	Uncharacterized conserved protein, UPF0335 family	85
647645373	912	21.81	1	532	2	490	1.0e-47	185	COG0591	Na+/proline symporter	493
647645375	431	20.82	106	426	10	313	3.0e-09	57.2	COG3800	Predicted transcriptional regulator	332
647645376	454	27.23	36	425	2	366	3.0e-36	146	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
647645377	347	30.12	3	344	1	295	7.0e-44	171	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
647645378	399	30.88	21	371	7	305	7.0e-36	144	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
647645379	254	38.46	3	249	4	250	4.0e-74	271	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
647645380	251	49.58	21	251	4	237	7.0e-74	270	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
647645381	497	34.73	1	496	11	526	4.0e-101	362	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647645382	164	39.47	13	164	1	139	6.0e-22	97.1	COG0511	Biotin carboxyl carrier protein	140
647645384	211	54.12	2	191	21	212	3.0e-68	251	COG2360	Leu/Phe-tRNA-protein transferase	221
647645387	127	52.85	12	127	2	118	5.0e-23	100	COG3761	NADH:ubiquinone oxidoreductase 17.2 kD subunit	118
647645388	120	31.71	5	118	7	129	7.0e-17	79.6	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
647645389	421	71.81	16	421	1	408	0.0e+00	695	COG1219	ATP-dependent protease Clp, ATPase subunit	408
647645390	215	67.34	11	209	2	200	9.0e-81	292	COG0740	ATP-dependent protease ClpP, protease subunit	200
647645392	676	49.17	24	676	1	616	0.0e+00	617	COG3211	Secreted phosphatase, PhoX family	616
647645393	325	36.79	6	323	13	317	1.0e-74	273	COG4531	ABC-type Zn2+ transport system, periplasmic component/surface adhesin	318
647645394	160	31.91	15	155	1	140	6.0e-24	103	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
647645395	244	42.52	1	235	2	254	5.0e-69	254	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
647645396	263	40.53	1	263	9	272	3.0e-42	165	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
647645397	133	35.43	5	130	7	128	1.0e-16	79.2	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
647645398	229	47.26	1	229	1	237	2.0e-69	255	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
647645399	251	48.4	2	247	1	250	3.0e-68	251	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
647645400	327	36.36	6	319	4	308	2.0e-37	149	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
647645401	305	40	1	305	1	293	6.0e-36	144	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
647645402	381	28.57	19	357	1	357	7.0e-36	144	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
647645403	396	52.74	7	384	23	405	3.0e-123	435	COG3844	Kynureninase	407
647645404	532	32.05	26	530	5	518	1.0e-107	383	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
647645405	384	41.3	14	382	5	388	4.0e-67	248	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647645406	262	33.08	1	259	4	257	6.0e-46	177	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647645407	156	28.69	17	138	1	121	6.0e-11	60.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
647645408	243	26.92	1	224	6	224	1.0e-31	130	COG0300	Short-chain dehydrogenase	265
647645409	764	41.94	394	747	4	352	3.0e-104	373	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
647645412	996	21.22	3	444	1	423	2.0e-36	148	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647645414	301	28.77	20	295	104	379	9.0e-38	150	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
647645415	689	25.98	158	667	144	613	1.0e-51	198	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
647645417	347	53.29	10	342	2	330	9.0e-114	403	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
647645418	277	50.93	5	273	7	274	2.0e-87	315	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
647645419	324	41.14	18	312	4	302	7.0e-78	284	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
647645420	334	24.52	46	334	1	306	5.0e-23	101	COG3734	2-keto-3-deoxy-galactonokinase	306
647645421	224	36	63	207	31	180	2.0e-19	89.6	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
647645422	433	16.14	9	419	12	426	1.0e-08	54.7	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
647645425	186	32.64	42	185	47	189	1.0e-18	86.1	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
647645427	388	23.96	4	377	3	381	6.0e-34	138	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647645429	323	37.81	9	313	1	308	8.0e-57	214	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647645434	939	35.66	27	428	1	397	5.0e-95	342	COG0004	Ammonia channel protein AmtB	409
647645435	413	42.93	2	406	1	382	1.0e-108	386	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
647645436	370	27.69	5	347	23	393	1.0e-71	263	COG0019	Diaminopimelate decarboxylase	394
647645440	1416	39.34	204	470	2	268	2.0e-60	229	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
647645444	205	32.84	5	203	9	202	3.0e-25	108	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
647645445	571	21.39	1	343	1	327	1.0e-17	85.1	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
647645446	262	53.91	7	262	6	261	1.0e-95	342	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
647645447	369	44.65	99	369	2	267	1.0e-60	227	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
647645448	632	38.75	8	606	100	710	1.0e-125	443	COG2217	Cation transport ATPase	713
647645450	334	32.86	8	319	2	350	5.0e-54	205	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
647645452	597	41.57	152	596	14	445	4.0e-110	392	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
647645453	494	28.67	215	482	23	319	3.0e-45	176	COG0280	Phosphotransacetylase	327
647645454	408	43.18	5	392	3	393	3.0e-117	415	COG0282	Acetate kinase	396
647645458	724	61.26	4	723	10	730	0.0e+00	1040	COG0376	Catalase (peroxidase I)	730
647645459	313	35.52	4	291	1	288	1.0e-40	160	COG0583	DNA-binding transcriptional regulator, LysR family	297
647645460	298	28.04	4	293	1	290	2.0e-26	113	COG0583	DNA-binding transcriptional regulator, LysR family	297
647645461	165	20.14	8	151	3	137	4.0e-07	47.9	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
647645462	531	20.37	12	485	4	423	2.0e-21	97.7	COG4529	Uncharacterized NAD(P)/FAD-binding protein YdhS	474
647645473	389	37.94	1	367	14	374	1.0e-87	317	COG1686	D-alanyl-D-alanine carboxypeptidase	389
647645474	210	45.15	4	208	2	206	8.0e-53	200	COG0125	Thymidylate kinase	208
647645476	268	42.19	5	258	1	254	2.0e-72	265	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
647645477	266	31.25	2	262	1	261	7.0e-42	164	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
647645478	309	31.29	1	309	2	308	1.0e-33	137	COG0679	Predicted permease	311
647645479	214	24.07	3	201	1	210	2.0e-11	62.5	COG0625	Glutathione S-transferase	211
647645482	576	46.84	9	561	12	564	0.0e+00	588	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
647645484	298	19.93	1	298	2	268	7.0e-12	64.7	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
647645485	247	39.24	1	236	5	238	1.0e-55	209	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
647645487	360	27.43	5	336	17	346	1.0e-42	167	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
647645488	730	25.73	250	589	5	330	3.0e-33	137	COG0642	Signal transduction histidine kinase	336
647645489	348	33.14	6	341	37	379	3.0e-53	202	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
647645490	233	33.5	22	225	4	208	5.0e-41	161	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
647645491	587	25	3	581	113	753	3.0e-95	342	COG4993	Glucose dehydrogenase	773
647645494	263	28.84	40	252	64	275	1.0e-08	53.8	COG0842	ABC-type multidrug transport system, permease component	286
647645495	238	42.15	1	220	2	224	2.0e-56	212	COG1131	ABC-type multidrug transport system, ATPase component	293
647645497	314	25.17	16	304	44	340	2.0e-26	113	COG3391	DNA-binding beta-propeller fold protein YncE	381
647645500	299	19.05	47	293	27	265	5.0e-08	51.9	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
647645501	173	41.5	1	146	1	145	3.0e-30	124	COG3427	Carbon monoxide dehydrogenase subunit G	146
647645502	156	59.46	1	148	6	153	4.0e-57	213	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
647645503	789	38.95	7	787	6	730	0.0e+00	582	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
647645504	262	34.88	1	262	1	280	4.0e-49	188	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
647645505	292	27.05	29	289	36	325	7.0e-30	124	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
647645506	700	25.1	11	459	18	480	1.0e-31	131	COG3901	Regulator of nitric oxide reductase transcription	482
647645509	490	32.49	28	489	3	443	1.0e-89	323	COG0174	Glutamine synthetase	443
647645510	407	19.93	24	265	25	314	1.0e-08	54.4	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
647645513	254	26.86	14	252	1	240	3.0e-30	125	COG1414	DNA-binding transcriptional regulator, IclR family	246
647645515	380	36.01	1	379	1	376	8.0e-66	244	COG1454	Alcohol dehydrogenase, class IV	377
647645516	495	58.27	1	495	4	496	0.0e+00	753	COG0554	Glycerol kinase	499
647645517	573	20.93	54	519	20	432	6.0e-21	95.9	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
647645518	90	59.55	3	90	9	97	1.0e-16	78.1	COG5477	Predicted small integral membrane protein	97
647645519	279	35.61	7	279	3	280	8.0e-49	187	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
647645520	290	31.16	1	289	4	295	3.0e-45	175	COG1175	ABC-type sugar transport system, permease component	295
647645521	359	40.97	1	348	1	335	1.0e-93	336	COG3839	ABC-type sugar transport system, ATPase component	338
647645522	362	36.96	1	349	2	338	2.0e-85	309	COG3839	ABC-type sugar transport system, ATPase component	338
647645523	533	44.19	7	526	10	504	0.0e+00	477	COG0578	Glycerol-3-phosphate dehydrogenase	532
647645524	252	44.05	1	252	1	252	3.0e-64	238	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
647645525	291	27.8	8	280	12	288	2.0e-41	163	COG1175	ABC-type sugar transport system, permease component	295
647645526	267	28.62	8	267	12	280	1.0e-35	143	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
647645530	543	29.97	191	532	44	408	9.0e-34	138	COG0840	Methyl-accepting chemotaxis protein	408
647645532	316	29.67	58	300	47	289	3.0e-13	69.6	COG1276	Putative copper export protein	289
647645533	119	28.33	5	119	7	126	7.0e-13	66.1	COG2372	Copper-binding protein CopC (methionine-rich)	127
647645535	1059	48.03	1	1040	1	1025	0.0e+00	1158	COG3696	Cu/Ag efflux pump CusA	1027
647645536	668	24.55	22	320	32	353	4.0e-17	83.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
647645539	441	27.3	162	439	41	327	1.0e-30	127	COG0642	Signal transduction histidine kinase	336
647645540	303	24.23	19	239	9	233	1.0e-15	77.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647645547	371	33.96	43	346	54	353	2.0e-53	202	COG1858	Cytochrome c peroxidase	364
647645548	155	39.58	5	148	6	149	3.0e-24	104	COG2847	Copper(I)-binding protein	151
647645551	360	26.71	1	332	16	319	4.0e-33	135	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
647645552	347	43.33	21	347	7	332	8.0e-50	191	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
647645553	248	38.34	1	241	1	253	6.0e-56	210	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
647645559	252	42.69	1	250	2	254	7.0e-56	210	COG1484	DNA replication protein DnaC	254
647645561	300	33.47	44	294	2	232	1.0e-17	84.3	COG2801	Transposase InsO and inactivated derivatives	232
647645563	365	23.66	2	224	52	270	1.0e-28	120	COG4584	Transposase	278
647645566	645	21.87	10	635	78	718	2.0e-40	161	COG1033	Predicted exporter protein, RND superfamily	727
647645567	166	35.71	4	164	2	169	6.0e-25	106	COG1755	Uncharacterized protein YpbQ, isoprenylcysteine carboxyl methyltransferase (ICMT) family	172
647645568	354	36.93	4	347	3	350	5.0e-72	265	COG3424	Predicted naringenin-chalcone synthase	356
647645571	356	21.71	22	354	112	446	9.0e-18	84.6	COG1231	Monoamine oxidase	450
647645572	654	31.65	438	652	6	221	3.0e-31	130	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
647645574	333	43.82	4	333	7	345	2.0e-70	259	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
647645575	469	47.95	4	436	1	438	0.0e+00	461	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
647645577	160	41.01	5	142	57	193	5.0e-38	150	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
647645581	293	22.71	7	229	8	227	2.0e-22	99	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647645582	151	40.71	2	141	18	157	5.0e-24	103	COG2193	Bacterioferritin (cytochrome b1)	157
647645583	557	44.62	1	129	1	130	2.0e-32	134	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
647645586	252	42.69	1	250	2	254	7.0e-56	210	COG1484	DNA replication protein DnaC	254
647645587	442	23.66	2	224	52	270	4.0e-28	119	COG4584	Transposase	278
647645588	289	48.6	8	285	2	285	5.0e-92	330	COG3129	23S rRNA A1618 N6-methylase RlmF	292
647645589	511	50	1	498	1	494	0.0e+00	483	COG3333	TctA family transporter	504
647645592	223	38.96	1	223	1	229	1.0e-45	176	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647645593	459	27.03	160	451	36	328	6.0e-29	122	COG0642	Signal transduction histidine kinase	336
647645594	342	21.61	45	334	1	295	9.0e-18	84.8	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
647645595	196	27.5	78	196	4	110	2.0e-08	52.6	COG0607	Rhodanese-related sulfurtransferase	110
647645597	333	25	1	315	17	331	1.0e-10	61	COG2807	Cyanate permease	395
647645599	200	57.63	4	175	59	235	4.0e-25	108	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
647645602	368	37.15	15	334	1	309	5.0e-58	218	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
647645603	396	29.49	10	386	5	386	3.0e-52	199	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647645604	527	38.91	16	519	13	524	4.0e-123	435	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647645605	396	34.21	57	359	5	305	1.0e-47	183	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647645606	178	21.21	6	170	7	166	2.0e-10	58.8	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647645607	378	20.29	2	342	6	326	1.0e-23	104	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647645608	258	37.35	1	254	3	256	4.0e-45	174	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647645609	300	36.53	1	270	2	257	8.0e-49	187	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647645610	246	29.78	4	223	2	225	7.0e-29	120	COG2186	DNA-binding transcriptional regulator, FadR family	241
647645612	253	30.24	6	252	2	246	1.0e-27	117	COG0368	Cobalamin synthase	246
647645613	341	42.17	13	338	2	333	2.0e-74	272	COG2038	NaMN:DMB phosphoribosyltransferase	347
647645614	169	48	3	169	1	175	2.0e-48	185	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
647645615	207	51.27	11	207	5	198	2.0e-65	242	COG2109	ATP:corrinoid adenosyltransferase	198
647645617	599	26.55	8	599	5	608	2.0e-68	254	COG4206	Outer membrane cobalamin receptor protein	608
647645618	324	23.71	4	323	8	350	1.0e-39	157	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
647645619	313	42.14	1	313	3	315	1.0e-67	250	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
647645620	241	22.67	6	211	43	262	3.0e-08	52.7	COG4542	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic...	293
647645621	172	51.3	19	168	2	153	9.0e-51	192	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
647645622	583	56.61	12	543	5	539	0.0e+00	673	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
647645623	287	49.3	3	287	25	299	3.0e-87	314	COG2421	Acetamidase/formamidase	305
647645624	546	33.52	1	515	6	528	6.0e-80	291	COG0747	ABC-type transport system, periplasmic component	556
647645625	306	46.2	1	306	1	316	8.0e-88	317	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647645626	301	48.79	13	300	5	289	3.0e-70	258	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647645627	199	29.31	17	186	15	188	3.0e-25	108	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
647645628	350	19.71	1	315	16	356	3.0e-21	96.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
647645631	602	45.63	26	586	3	563	0.0e+00	597	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
647645633	516	33.27	13	516	34	533	3.0e-80	293	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647645634	361	42.61	1	346	4	346	1.0e-82	300	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
647645635	469	35.71	8	461	1	456	2.0e-80	293	COG0277	FAD/FMN-containing dehydrogenase	459
647645636	1170	46.36	1	552	1	556	0.0e+00	558	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
647645637	198	38.12	1	196	45	246	9.0e-50	189	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
647645638	271	28.12	29	243	32	249	3.0e-25	109	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
647645639	276	45.64	1	241	1	221	1.0e-66	247	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
647645640	272	28.46	8	267	6	255	3.0e-31	129	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
647645641	356	21.57	1	300	2	304	2.0e-20	93.3	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
647645642	664	34.83	29	644	18	630	1.0e-90	327	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
647645643	378	24.25	4	326	6	321	2.0e-16	80.7	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
647645645	261	39.69	3	258	2	250	3.0e-37	149	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647645647	339	49.4	6	338	20	354	4.0e-90	325	COG5621	Predicted secreted hydrolase	354
647645648	781	17.63	370	775	5	417	6.0e-08	53.2	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
647645649	218	43.18	2	217	1	220	1.0e-64	239	COG1136	ABC-type lipoprotein export system, ATPase component	226
647645650	221	21.14	12	185	4	178	2.0e-10	59.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647645651	283	45.7	25	280	3	243	1.0e-73	269	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
647645652	257	33.6	8	252	12	258	3.0e-45	175	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
647645653	341	22.69	6	337	11	334	1.0e-25	110	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
647645656	543	51.75	1	536	5	536	0.0e+00	614	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
647645657	292	48.89	23	291	18	287	1.0e-69	256	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647645658	355	44.88	19	350	2	313	2.0e-79	289	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647645659	534	25.05	10	523	16	540	2.0e-60	227	COG0747	ABC-type transport system, periplasmic component	556
647645660	492	34.97	3	447	1	421	2.0e-60	226	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
647645661	598	34.26	1	446	2	468	5.0e-78	286	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
647645662	314	25.75	18	314	3	297	2.0e-23	103	COG0583	DNA-binding transcriptional regulator, LysR family	297
647645663	372	32.76	2	340	1	341	8.0e-65	241	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
647645664	369	36.98	20	355	6	343	5.0e-61	228	COG4603	ABC-type uncharacterized transport system, permease component	356
647645665	308	42.11	13	296	8	292	1.0e-64	240	COG1079	ABC-type uncharacterized transport system, permease component	304
647645666	336	24.16	14	272	3	261	1.0e-28	120	COG0388	Predicted amidohydrolase	274
647645667	225	31.48	17	225	1	203	1.0e-35	143	COG1335	Nicotinamidase-related amidase	205
647645668	508	43.29	12	506	5	501	0.0e+00	515	COG3845	ABC-type uncharacterized transport system, ATPase component	501
647645669	222	30.84	14	220	1	202	3.0e-29	121	COG1335	Nicotinamidase-related amidase	205
647645671	426	53.48	13	426	1	417	0.0e+00	507	COG0014	Gamma-glutamyl phosphate reductase	417
647645673	386	37.3	1	366	3	369	3.0e-86	312	COG0263	Glutamate 5-kinase	369
647645674	400	40.78	1	400	1	392	3.0e-85	309	COG0183	Acetyl-CoA acetyltransferase	392
647645675	224	51.56	1	224	1	225	3.0e-76	278	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
647645676	235	57.21	1	222	1	220	8.0e-78	283	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
647645677	247	36.68	8	230	1	229	6.0e-44	170	COG1414	DNA-binding transcriptional regulator, IclR family	246
647645678	510	35.54	7	510	2	528	1.0e-99	357	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647645679	198	21.16	1	189	15	196	7.0e-07	47.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647645680	365	20.95	1	357	2	366	2.0e-07	50.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
647645681	1027	24.51	2	1002	1	1003	0.0e+00	605	COG0841	Multidrug efflux pump subunit AcrB	1009
647645682	327	44.48	5	323	3	324	1.0e-96	346	COG0158	Fructose-1,6-bisphosphatase	326
647645684	279	45.08	1	263	1	264	5.0e-49	188	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
647645685	291	44.89	1	273	1	274	3.0e-50	192	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
647645686	298	50.6	20	270	5	254	5.0e-87	314	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
647645687	296	35.25	1	291	8	301	7.0e-76	277	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
647645688	139	38.76	9	137	7	135	3.0e-28	117	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
647645689	228	24.73	39	220	13	194	4.0e-10	58.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647645690	494	41.9	25	378	15	347	7.0e-70	258	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
647645691	299	29.11	6	290	5	288	5.0e-33	134	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
647645692	406	25.74	89	386	2	281	3.0e-36	146	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
647645693	494	33.74	7	488	2	454	6.0e-112	398	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
647645694	262	51.28	6	237	1	226	9.0e-66	243	COG0120	Ribose 5-phosphate isomerase	227
647645695	366	37.54	20	360	4	348	1.0e-73	270	COG3424	Predicted naringenin-chalcone synthase	356
647645696	162	35.8	5	159	4	165	3.0e-25	107	COG1755	Uncharacterized protein YpbQ, isoprenylcysteine carboxyl methyltransferase (ICMT) family	172
647645697	228	32.21	5	207	3	205	4.0e-20	91.8	COG0625	Glutathione S-transferase	211
647645698	457	47.7	171	453	1	262	9.0e-78	284	COG1760	L-serine deaminase	262
647645699	226	22.41	1	224	3	207	5.0e-16	78.1	COG0778	Nitroreductase	207
647645700	316	30.77	1	282	1	286	3.0e-48	186	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
647645702	303	39.74	1	299	2	276	2.0e-60	226	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
647645703	195	26.78	1	182	2	184	5.0e-11	61.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647645705	460	47.87	35	354	2	329	1.0e-94	340	COG0460	Homoserine dehydrogenase	333
647645706	579	39.15	58	544	6	482	2.0e-89	323	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
647645708	104	38.46	1	103	1	95	2.0e-17	80.4	COG1359	Quinol monooxygenase YgiN	100
647645709	331	39.44	147	322	3	181	2.0e-36	146	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
647645711	520	46.88	11	519	20	526	0.0e+00	536	COG5598	Trimethylamine:corrinoid methyltransferase	526
647645712	241	28.45	11	237	3	218	3.0e-24	105	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
647645714	467	32.52	17	465	3	435	2.0e-59	223	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
647645719	430	59.07	1	429	1	430	0.0e+00	629	COG0104	Adenylosuccinate synthase	430
647645722	119	37.18	1	76	1	78	1.0e-10	59.1	COG1314	Preprotein translocase subunit SecG	86
647645723	549	58.97	3	547	2	531	0.0e+00	835	COG0504	CTP synthase (UTP-ammonia lyase)	533
647645724	260	42.02	2	251	1	255	2.0e-57	216	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
647645725	97	45.83	1	95	1	96	1.0e-21	94.2	COG5470	Uncharacterized conserved protein, DUF1330 family	96
647645726	145	31.15	20	141	26	147	2.0e-10	58.4	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
647645727	158	31.65	13	151	6	144	3.0e-17	81.5	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
647645728	258	61.04	6	253	5	253	3.0e-99	354	COG4598	ABC-type histidine transport system, ATPase component	256
647645729	244	30.86	1	243	1	269	2.0e-29	122	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
647645730	259	31.2	1	249	16	230	2.0e-34	139	COG4215	ABC-type arginine transport system, permease component	230
647645731	268	30.67	31	252	8	226	4.0e-34	138	COG4160	ABC-type arginine/histidine transport system, permease component	228
647645732	444	35.6	4	443	8	443	5.0e-101	361	COG0174	Glutamine synthetase	443
647645733	226	27.94	1	192	2	194	1.0e-31	129	COG0518	GMP synthase - Glutamine amidotransferase domain	198
647645734	452	35.95	7	449	1	441	1.0e-105	376	COG0174	Glutamine synthetase	443
647645735	434	29.11	33	413	1	387	3.0e-53	203	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647645736	392	30	11	379	12	367	3.0e-52	199	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
647645737	197	36.32	17	196	9	193	1.0e-27	116	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
647645739	603	45.52	152	597	8	443	2.0e-129	456	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
647645740	420	42.86	35	396	43	404	1.0e-97	350	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
647645742	222	26.37	38	220	80	280	8.0e-12	64	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647645745	251	24.2	5	222	1	217	6.0e-13	68.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647645748	648	51.63	36	648	1	586	0.0e+00	722	COG0441	Threonyl-tRNA synthetase	589
647645749	100	50	9	88	24	103	3.0e-14	70.2	COG5572	Uncharacterized membrane protein	104
647645750	282	45.9	12	277	3	266	4.0e-79	288	COG3220	Uncharacterized conserved protein, UPF0276 family	282
647645753	105	30.56	1	97	2	109	8.0e-16	75.6	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
647645756	399	40.1	8	393	27	409	3.0e-73	269	COG2124	Cytochrome P450	411
647645757	318	31.64	42	310	9	273	3.0e-52	199	COG1351	Thymidylate synthase ThyX	273
647645760	144	26.28	4	124	2	138	3.0e-11	61.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
647645763	243	28.92	1	241	36	282	2.0e-38	153	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
647645765	88	31.4	1	85	7	91	5.0e-13	66	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
647645767	400	45.41	8	399	3	392	4.0e-113	401	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
647645769	452	35.94	11	442	16	441	7.0e-58	218	COG0534	Na+-driven multidrug efflux pump	455
647645770	370	24.91	56	294	43	304	5.0e-18	85.8	COG4188	Predicted dienelactone hydrolase	365
647645771	290	24.91	6	290	2	279	2.0e-19	90.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647645773	653	47.6	10	653	1	635	0.0e+00	786	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
647645775	133	30.7	20	133	23	136	2.0e-16	78.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
647645778	227	42.47	5	222	1	218	3.0e-69	254	COG1136	ABC-type lipoprotein export system, ATPase component	226
647645779	448	37.79	27	448	1	408	1.0e-89	323	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
647645781	446	36.19	1	425	1	369	2.0e-97	349	COG0442	Prolyl-tRNA synthetase	500
647645782	412	36.8	7	412	5	413	2.0e-77	283	COG2195	Di- or tripeptidase	414
647645783	358	36.12	11	345	18	349	3.0e-40	159	COG0628	Predicted PurR-regulated permease PerM	355
647645785	724	51.45	26	711	9	694	0.0e+00	859	COG0855	Polyphosphate kinase	696
647645786	524	31.64	36	432	1	413	4.0e-73	269	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
647645789	226	21.51	51	219	1	171	2.0e-19	89.6	COG1076	DnaJ-domain-containing proteins 1	174
647645790	149	38.56	2	149	15	167	5.0e-28	116	COG1247	L-amino acid N-acyltransferase YncA	169
647645792	709	63.44	5	545	2	548	0.0e+00	734	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
647645795	681	53.22	1	681	1	644	0.0e+00	861	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
647645800	510	59.73	1	510	11	526	0.0e+00	718	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
647645801	396	21.27	4	393	6	393	3.0e-20	93	COG2814	Predicted arabinose efflux permease, MFS family	394
647645802	483	50.45	157	482	1	331	5.0e-106	378	COG3800	Predicted transcriptional regulator	332
647645803	580	52.49	26	563	3	540	0.0e+00	516	COG2303	Choline dehydrogenase or related flavoprotein	542
647645804	483	47.9	7	478	1	471	0.0e+00	499	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647645805	502	31.82	3	447	4	471	7.0e-76	278	COG3119	Arylsulfatase A or related enzyme	475
647645806	186	24.46	2	181	10	193	7.0e-06	43.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647645808	198	51.01	1	196	2	199	2.0e-50	192	COG1279	Arginine exporter protein ArgO	202
647645810	247	61.41	1	240	1	241	4.0e-93	334	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
647645813	590	22.34	121	590	54	456	3.0e-27	117	COG0471	Di- and tricarboxylate transporter	461
647645815	270	51.85	1	270	1	266	1.0e-97	349	COG1692	Calcineurin-like phosphoesterase	266
647645817	187	38.1	6	183	3	188	5.0e-27	114	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
647645818	482	40.72	43	482	9	448	9.0e-105	374	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
647645819	430	30	33	427	23	405	1.0e-73	270	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
647645821	452	35.52	1	436	1	421	7.0e-68	251	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
647645822	268	36.36	18	264	11	260	6.0e-50	190	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
647645824	258	43.08	8	256	6	228	2.0e-32	132	COG0670	Integral membrane protein, interacts with FtsH	233
647645825	229	37.12	3	229	1	229	2.0e-25	109	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
647645826	55	46.81	7	53	4	50	6.0e-08	49.1	COG0267	Ribosomal protein L33	50
647645829	495	49.1	1	492	1	474	0.0e+00	469	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
647645830	95	44.21	1	95	1	95	4.0e-22	96.4	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
647645831	230	29.39	1	230	7	250	1.0e-27	116	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
647645834	151	52.14	6	145	11	150	4.0e-42	163	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
647645835	336	44.07	19	246	4	239	4.0e-59	222	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
647645838	391	31.58	11	385	9	383	7.0e-52	198	COG3853	Uncharacterized conserved protein YaaN involved in tellurite resistance	386
647645840	369	31.86	1	314	1	316	4.0e-58	219	COG4260	Membrane protease subunit, stomatin/prohibitin family, contains C-terminal Zn-ribbon domain	345
647645843	224	21.43	3	223	1	205	1.0e-15	76.5	COG0778	Nitroreductase	207
647645844	147	57.24	1	145	1	145	1.0e-55	208	COG1490	D-Tyr-tRNAtyr deacylase	145
647645845	396	24.22	4	377	1	342	4.0e-17	82.7	COG1566	Multidrug resistance efflux pump	352
647645846	740	30.9	77	730	44	696	2.0e-125	443	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
647645847	440	19.95	87	440	56	451	7.0e-10	59	COG1538	Outer membrane protein TolC	457
647645849	664	35.74	6	532	11	553	7.0e-114	405	COG2936	Predicted acyl esterase	563
647645850	534	26.51	12	531	1	556	2.0e-75	276	COG0747	ABC-type transport system, periplasmic component	556
647645851	318	38.49	4	318	1	317	7.0e-73	267	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647645852	271	34.62	3	259	19	278	1.0e-52	200	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647645853	545	43.41	1	529	1	539	0.0e+00	592	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
647645855	313	33.22	24	302	17	309	1.0e-43	170	COG0657	Acetyl esterase/lipase	312
647645856	610	32.64	1	561	2	533	5.0e-95	342	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647645858	598	42.21	23	593	4	567	0.0e+00	461	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647645860	504	40.32	12	499	22	526	3.0e-109	389	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647645861	242	34.36	15	237	8	230	8.0e-34	137	COG3473	Maleate cis-trans isomerase	238
647645862	381	27.98	4	378	5	384	2.0e-46	180	COG0006	Xaa-Pro aminopeptidase	384
647645863	346	28.24	36	330	21	306	2.0e-35	143	COG1171	Threonine dehydratase	347
647645865	746	23.28	106	742	59	723	5.0e-56	212	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
647645866	152	55.26	1	150	4	155	7.0e-53	199	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
647645867	371	63.78	2	371	1	366	0.0e+00	538	COG1062	Zn-dependent alcohol dehydrogenase	366
647645868	301	33	7	301	1	293	2.0e-30	126	COG0583	DNA-binding transcriptional regulator, LysR family	297
647645869	127	34.15	7	126	1	123	2.0e-18	85.1	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
647645870	243	47.23	5	239	4	226	2.0e-71	262	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
647645871	201	47.09	2	201	22	226	9.0e-52	196	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
647645872	278	28.33	1	275	1	297	2.0e-45	176	COG3246	Uncharacterized conserved protein, DUF849 family	298
647645873	391	29.53	1	391	16	410	1.0e-60	227	COG2124	Cytochrome P450	411
647645875	765	23.09	7	443	1	452	6.0e-37	149	COG3119	Arylsulfatase A or related enzyme	475
647645884	575	43.28	19	553	5	538	0.0e+00	474	COG0405	Gamma-glutamyltranspeptidase	539
647645885	386	39.37	4	318	2	342	9.0e-69	254	COG2951	Membrane-bound lytic murein transglycosylase B	343
647645886	323	40.94	7	321	2	319	3.0e-83	302	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
647645888	446	36.19	3	441	2	467	1.0e-87	316	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
647645889	455	36.56	1	451	2	447	4.0e-100	358	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
647645890	196	28.89	1	180	5	182	2.0e-35	142	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
647645891	364	30.6	7	362	3	363	5.0e-71	261	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
647645892	308	31.84	43	306	1	256	8.0e-33	134	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
647645893	271	35.04	1	271	10	282	8.0e-43	167	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
647645894	269	33.98	13	268	24	281	2.0e-41	162	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
647645895	263	49.8	1	245	3	247	9.0e-83	300	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
647645896	218	39.52	1	209	1	208	4.0e-36	144	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
647645897	151	41.07	37	148	7	118	3.0e-16	77.9	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
647645898	243	46.52	10	239	2	230	3.0e-54	205	COG1346	Putative effector of murein hydrolase	230
647645900	218	33.18	5	218	1	186	1.0e-32	133	COG3658	Cytochrome b	192
647645906	418	46.52	45	418	1	373	1.0e-84	307	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647645907	190	22.58	21	175	1	155	1.0e-10	60	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647645908	321	39.24	5	319	11	326	1.0e-69	256	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647645909	251	39.76	4	247	3	249	3.0e-43	168	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647645910	343	43.04	29	343	1	312	4.0e-99	354	COG3958	Transketolase, C-terminal subunit	312
647645911	284	48.95	11	249	6	243	2.0e-87	316	COG3959	Transketolase, N-terminal subunit	243
647645912	389	42.71	8	389	1	389	8.0e-97	347	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
647645913	657	46.32	1	651	3	661	0.0e+00	741	COG0021	Transketolase	663
647645914	474	42.24	214	445	1	230	2.0e-52	200	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
647645915	311	25.15	1	307	2	327	3.0e-31	129	COG0547	Anthranilate phosphoribosyltransferase	338
647645916	858	33.29	4	673	41	761	1.0e-125	444	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
647645917	111	42.72	1	101	2	104	4.0e-26	109	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
647645918	812	55.57	1	797	2	785	0.0e+00	1014	COG1251	NAD(P)H-nitrite reductase, large subunit	793
647645919	562	50	1	251	1	242	2.0e-79	290	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
647645920	357	26.97	49	352	1	251	1.0e-36	147	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
647645921	456	26.09	7	369	9	335	8.0e-37	148	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
647645923	382	27.04	2	311	29	329	1.0e-35	144	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
647645924	206	36.84	16	205	5	194	7.0e-39	153	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
647645925	235	37.17	1	224	4	228	7.0e-30	124	COG1802	DNA-binding transcriptional regulator, GntR family	230
647645926	328	43.38	3	328	1	352	6.0e-97	347	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
647645927	426	17.7	11	361	3	321	2.0e-18	87.1	COG0687	Spermidine/putrescine-binding periplasmic protein	363
647645928	287	36.49	4	285	1	282	6.0e-49	187	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
647645929	279	36.3	1	268	3	267	1.0e-42	166	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
647645930	211	39.72	2	211	3	216	3.0e-41	161	COG4126	Asp/Glu/hydantoin racemase	230
647645934	467	26.09	124	321	7	213	3.0e-27	116	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
647645935	337	24.7	7	323	37	367	2.0e-20	93.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647645938	411	20.54	6	397	4	406	2.0e-12	67.4	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
647645940	845	32.49	315	590	74	336	1.0e-35	145	COG0642	Signal transduction histidine kinase	336
647645941	187	44	61	184	29	153	6.0e-32	130	COG3915	Uncharacterized protein	155
647645942	301	50.18	7	290	1	284	3.0e-100	358	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
647645943	463	40.24	18	258	4	247	5.0e-60	225	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
647645944	204	38.46	1	203	1	208	4.0e-39	154	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
647645945	486	16.89	40	469	19	449	2.0e-13	70.9	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
647645947	370	31.37	1	350	17	372	1.0e-44	174	COG2843	Poly-gamma-glutamate biosynthesis protein CapA/YwtB (capsule formation), metallophosphatase superfamily	372
647645948	141	40.74	27	134	13	119	5.0e-24	103	COG1733	DNA-binding transcriptional regulator, HxlR family	120
647645949	248	51.28	1	234	1	232	3.0e-65	241	COG3967	Short-chain dehydrogenase involved in D-alanine esterification of teichoic acids	245
647645952	97	42.68	8	89	4	85	1.0e-15	74.5	COG1937	DNA-binding transcriptional regulator, FrmR family	89
647645954	231	28.24	8	222	3	212	1.0e-11	63.7	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
647645956	307	35.82	7	280	33	302	5.0e-39	155	COG0501	Zn-dependent protease with chaperone function	302
647645957	644	29.58	6	639	9	587	1.0e-73	271	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
647645961	162	43.84	18	155	3	148	2.0e-17	81.6	COG2165	Type II secretory pathway, pseudopilin PulG	149
647645962	401	20.39	55	395	44	387	2.0e-13	70	COG3297	Type II secretory pathway, component PulL	390
647645963	152	28.77	7	148	31	176	2.0e-10	58.9	COG3149	Type II secretory pathway, component PulM	181
647645964	500	48.35	12	492	20	500	0.0e+00	496	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
647645965	405	36.3	1	405	1	397	2.0e-84	306	COG1459	Type II secretory pathway, component PulF	397
647645969	285	23.44	3	216	2	255	4.0e-11	62.3	COG3156	Type II secretory pathway, component PulK	323
647645973	232	33.19	4	232	1	218	9.0e-40	157	COG0850	Septum formation inhibitor MinC	219
647645974	280	61.71	10	277	1	268	2.0e-111	395	COG2894	Septum formation inhibitor-activating ATPase MinD	272
647645975	104	49.44	1	89	1	87	3.0e-20	90.3	COG0851	Septum formation topological specificity factor MinE	88
647645978	196	18.62	1	188	8	193	3.0e-06	45.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647645981	317	31.85	1	314	1	302	6.0e-42	164	COG0385	Predicted Na+-dependent transporter	319
647645982	534	39.44	15	534	6	539	0.0e+00	503	COG0405	Gamma-glutamyltranspeptidase	539
647645984	391	40.91	1	374	4	373	2.0e-86	313	COG3333	TctA family transporter	504
647645986	287	32.08	2	286	1	289	2.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
647645987	405	46.06	5	397	6	397	0.0e+00	465	COG1812	Archaeal S-adenosylmethionine synthetase	400
647645988	218	29.17	26	215	1	184	9.0e-12	63.9	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
647645991	266	25.13	69	259	36	221	2.0e-12	66.5	COG2801	Transposase InsO and inactivated derivatives	232
647645992	252	42.69	1	250	2	254	7.0e-56	210	COG1484	DNA replication protein DnaC	254
647645993	442	23.66	2	224	52	270	4.0e-28	119	COG4584	Transposase	278
647645995	760	30.62	3	566	100	649	2.0e-103	370	COG0209	Ribonucleotide reductase alpha subunit	696
647645996	143	46.85	5	143	3	144	4.0e-36	143	COG5458	Uncharacterized protein	144
647645998	359	30.36	14	349	27	378	2.0e-25	110	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
647645999	502	32.45	9	499	1	429	2.0e-97	349	COG0124	Histidyl-tRNA synthetase	429
647646001	1177	44.78	4	1175	1	1139	0.0e+00	1160	COG0587	DNA polymerase III, alpha subunit	1139
647646002	468	51.67	3	464	9	486	0.0e+00	526	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
647646003	761	59.84	3	761	19	776	0.0e+00	995	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
647646004	258	26.64	1	250	14	259	7.0e-23	101	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
647646005	505	48.41	2	496	1	501	0.0e+00	585	COG3845	ABC-type uncharacterized transport system, ATPase component	501
647646007	360	40.62	2	353	1	348	4.0e-67	248	COG4603	ABC-type uncharacterized transport system, permease component	356
647646008	306	49.32	9	302	8	300	2.0e-69	256	COG1079	ABC-type uncharacterized transport system, permease component	304
647646009	359	37.35	1	332	9	345	1.0e-66	247	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
647646010	283	26.41	4	228	18	238	6.0e-22	98	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647646011	205	26.07	1	205	1	209	3.0e-20	91.8	COG0625	Glutathione S-transferase	211
647646012	333	38.49	22	324	1	313	3.0e-65	242	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
647646013	357	28.27	3	357	6	386	2.0e-30	126	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647646015	260	34.51	4	255	13	265	2.0e-57	215	COG3757	Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family	269
647646016	836	33.91	439	834	3	379	1.0e-79	291	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
647646017	473	35	278	455	3	181	1.0e-34	141	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
647646018	467	38.33	26	466	8	457	1.0e-87	317	COG0277	FAD/FMN-containing dehydrogenase	459
647646019	592	46.52	54	591	11	538	0.0e+00	524	COG0405	Gamma-glutamyltranspeptidase	539
647646020	328	45.37	8	326	5	324	1.0e-92	332	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
647646021	168	36.75	9	168	12	171	8.0e-35	139	COG3807	SH3-like domain	171
647646022	329	33.03	1	326	1	325	2.0e-53	202	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647646026	663	36.55	1	652	2	711	0.0e+00	527	COG0643	Chemotaxis protein histidine kinase CheA	716
647646027	144	24.46	2	140	31	165	5.0e-21	93.8	COG0835	Chemotaxis signal transduction protein	165
647646028	549	34.33	167	494	41	407	7.0e-33	135	COG0840	Methyl-accepting chemotaxis protein	408
647646029	166	25.66	6	157	19	165	2.0e-21	95.4	COG0835	Chemotaxis signal transduction protein	165
647646030	286	34.73	15	275	2	252	8.0e-56	210	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
647646031	368	44.97	6	362	2	348	4.0e-88	318	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
647646035	651	35.17	59	643	17	610	1.0e-129	457	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
647646037	471	41.18	2	468	45	518	3.0e-126	445	COG3540	Phosphodiesterase/alkaline phosphatase D	522
647646039	415	54.96	185	315	19	149	1.0e-43	170	COG5616	TolB amino-terminal domain (function unknown)	152
647646040	472	28.64	8	440	1	429	3.0e-70	259	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
647646041	360	44.1	16	333	1	300	3.0e-91	329	COG0031	Cysteine synthase	300
647646043	521	31.01	2	130	8	134	7.0e-22	98.9	COG3710	DNA-binding winged helix-turn-helix (wHTH) domain	148
647646045	574	34.9	14	199	13	204	6.0e-21	96.1	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
647646046	298	19.86	6	291	1	287	3.0e-24	106	COG0224	FoF1-type ATP synthase, gamma subunit	287
647646047	512	47.96	14	503	10	499	0.0e+00	547	COG0056	FoF1-type ATP synthase, alpha subunit	504
647646048	238	26.32	1	133	18	150	2.0e-07	49.5	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
647646049	95	40.26	5	81	3	79	2.0e-06	44	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
647646050	232	30.97	8	218	18	243	5.0e-33	134	COG0356	FoF1-type ATP synthase, membrane subunit a	246
647646053	130	24.03	1	126	4	130	3.0e-09	54.1	COG0355	FoF1-type ATP synthase, epsilon subunit	135
647646054	465	54.68	15	464	4	462	0.0e+00	624	COG0055	FoF1-type ATP synthase, beta subunit	468
647646055	457	40.61	3	457	1	446	0.0e+00	487	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
647646056	1075	31.5	622	1000	41	421	7.0e-06	47.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
647646060	149	31.34	6	138	4	123	2.0e-14	71.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
647646063	538	41.09	12	536	1	526	0.0e+00	477	COG3131	Periplasmic glucans biosynthesis protein	534
647646065	602	39.66	57	575	101	637	4.0e-119	422	COG2943	Membrane glycosyltransferase	736
647646066	377	38.07	1	352	33	372	4.0e-59	222	COG4645	Uncharacterized protein	410
647646067	278	16.47	7	248	5	251	3.0e-10	59.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
647646068	323	37.81	9	313	1	308	8.0e-57	214	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647646070	797	29.49	452	759	6	310	1.0e-30	128	COG0668	Small-conductance mechanosensitive channel	316
647646071	514	27.09	1	514	2	530	2.0e-75	277	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
647646072	533	34.15	17	532	2	530	4.0e-104	372	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647646073	573	29.69	3	550	1	528	2.0e-94	340	COG0659	Sulfate permease or related transporter, MFS superfamily	554
647646074	296	22.62	10	255	10	250	1.0e-22	101	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647646075	303	24.26	54	255	2	188	5.0e-12	65.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647646076	317	19.05	53	279	16	241	5.0e-14	72.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647646078	357	47.24	231	357	8	133	6.0e-34	138	COG3474	Cytochrome c2	135
647646080	556	28.96	107	528	48	473	1.0e-62	234	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
647646083	139	30.34	6	139	5	148	5.0e-10	57	COG5501	Predicted secreted protein	148
647646085	188	25	1	185	2	168	2.0e-18	85.4	COG2143	Thioredoxin-related protein	182
647646086	246	44.7	9	224	16	220	5.0e-27	114	COG0785	Cytochrome c biogenesis protein CcdA	220
647646088	102	35.79	9	102	8	102	2.0e-07	47.5	COG0640	DNA-binding transcriptional regulator, ArsR family	110
647646090	398	24.69	84	393	1	314	4.0e-32	132	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
647646091	339	27.91	1	326	9	316	6.0e-37	148	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
647646092	353	39.24	36	350	5	311	7.0e-56	211	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
647646095	321	41.82	2	319	13	341	5.0e-72	264	COG3569	DNA topoisomerase IB	354
647646097	264	38.58	10	263	1	254	8.0e-49	187	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
647646098	255	47.15	3	248	4	248	8.0e-77	280	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
647646099	339	21.3	6	338	7	329	2.0e-20	93.7	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
647646100	1067	32.21	750	1005	1	265	1.0e-37	152	COG1018	Ferredoxin-NADP reductase	266
647646101	333	30.18	6	333	4	314	2.0e-45	176	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647646102	229	53.78	5	227	2	220	5.0e-79	287	COG0036	Pentose-5-phosphate-3-epimerase	220
647646103	497	36.35	1	494	10	527	4.0e-98	352	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647646104	257	35.43	4	255	9	257	3.0e-34	138	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647646105	133	25	1	131	12	141	2.0e-16	78.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
647646106	377	29.32	1	370	1	381	1.0e-46	180	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647646107	401	34.07	1	398	1	388	9.0e-65	241	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647646108	698	40.56	287	568	1	285	2.0e-73	270	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
647646109	258	28.98	13	249	2	245	3.0e-29	122	COG1414	DNA-binding transcriptional regulator, IclR family	246
647646111	597	50.45	1	552	2	539	0.0e+00	614	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
647646112	639	22.67	1	617	4	548	3.0e-47	183	COG0747	ABC-type transport system, periplasmic component	556
647646113	341	34.82	4	338	2	316	1.0e-58	220	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647646114	384	44.44	150	383	59	286	3.0e-63	236	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647646115	247	25.32	30	240	3	235	2.0e-16	79.8	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
647646116	805	28.72	494	785	26	316	2.0e-31	131	COG0668	Small-conductance mechanosensitive channel	316
647646117	437	38.66	20	430	11	425	1.0e-110	393	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
647646118	401	40.53	17	387	11	379	1.0e-95	343	COG4671	Predicted glycosyl transferase	400
647646119	413	26.42	114	409	87	378	4.0e-27	115	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647646120	358	23.16	79	354	93	377	6.0e-16	78.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647646121	193	32.46	1	180	2	192	4.0e-24	104	COG0406	Broad specificity phosphatase PhoE	208
647646122	384	33.07	1	367	10	381	4.0e-51	195	COG4671	Predicted glycosyl transferase	400
647646123	117	36.89	21	117	11	112	2.0e-18	84.6	COG2824	Uncharacterized Zn-ribbon-containing protein	112
647646125	599	64.67	1	599	3	602	0.0e+00	1025	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
647646131	159	52.87	3	159	10	160	3.0e-49	187	COG5328	Uncharacterized protein, UPF0262 family	160
647646132	447	52.13	27	446	6	425	0.0e+00	528	COG0141	Histidinol dehydrogenase	425
647646134	423	59.1	1	423	1	421	0.0e+00	566	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
647646137	514	24.73	8	191	1	171	1.0e-14	74.8	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
647646142	692	20.2	1	595	1	522	1.0e-42	168	COG3593	Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains	581
647646143	613	17.22	25	585	20	614	4.0e-17	83.3	COG0210	Superfamily I DNA or RNA helicase	655
647646144	300	57.43	2	293	9	301	2.0e-102	365	COG4227	Antirestriction protein ArdC	316
647646146	595	30.04	98	585	80	555	1.0e-79	291	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
647646149	322	20.91	1	317	2	330	8.0e-21	94.9	COG0673	Predicted dehydrogenase	342
647646150	499	22.4	48	485	11	402	2.0e-29	124	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647646153	315	29.76	10	284	19	303	6.0e-35	141	COG0668	Small-conductance mechanosensitive channel	316
647646155	1104	56.76	284	1100	1	804	0.0e+00	1073	COG4196	Uncharacterized conserved protein, DUF2126 family	808
647646156	799	34.93	28	503	13	488	0.0e+00	468	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
647646157	292	30.21	1	282	11	296	1.0e-35	143	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
647646158	231	45.28	1	210	3	214	5.0e-72	264	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
647646159	250	59.92	1	247	1	246	3.0e-93	334	COG4674	ABC-type uncharacterized transport system, ATPase component	249
647646160	388	28.16	32	379	18	307	2.0e-34	139	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
647646161	644	40.34	355	642	11	297	5.0e-64	239	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
647646162	429	29.51	27	386	8	365	5.0e-61	228	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
647646164	917	29.1	515	898	1	408	1.0e-28	122	COG0840	Methyl-accepting chemotaxis protein	408
647646165	384	24.79	21	378	1	359	2.0e-41	163	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
647646167	367	29.59	5	365	22	372	1.0e-56	213	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
647646168	538	45.49	3	537	7	538	0.0e+00	476	COG2303	Choline dehydrogenase or related flavoprotein	542
647646169	325	32.71	64	325	8	253	6.0e-37	148	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
647646170	333	44.41	4	333	7	345	3.0e-70	258	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
647646171	469	47.6	4	435	1	437	2.0e-130	459	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
647646173	152	41.3	1	137	1	137	4.0e-30	123	COG1959	DNA-binding transcriptional regulator, IscR family	150
647646175	67	44.83	8	65	1	58	8.0e-06	42.2	COG3847	Flp pilus assembly protein, pilin Flp	58
647646176	390	27.14	120	387	93	359	6.0e-23	102	COG4963	Flp pilus assembly protein, ATPase CpaE	366
647646177	507	54.57	118	467	8	352	9.0e-115	407	COG4962	Pilus assembly protein, ATPase of CpaF family	355
647646178	317	32.36	6	312	3	304	4.0e-43	168	COG4965	Flp pilus assembly protein TadB	309
647646179	320	26.64	79	319	77	319	3.0e-14	72.9	COG2064	Pilus assembly protein TadC	320
647646180	143	31.79	1	137	3	153	4.0e-11	60.5	COG4961	Flp pilus assembly protein TadG	185
647646181	587	25.82	1	587	1	565	5.0e-32	133	COG4655	Uncharacterized membrane protein	565
647646184	548	31.8	15	548	4	541	8.0e-94	338	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
647646185	248	28.98	78	247	22	182	4.0e-18	85.3	COG3916	N-acyl-L-homoserine lactone synthetase	209
647646186	452	26.53	86	424	3	335	6.0e-38	152	COG0642	Signal transduction histidine kinase	336
647646188	434	34.76	61	433	9	377	2.0e-58	220	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647646189	182	24.06	1	182	1	180	1.0e-10	59.9	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
647646190	370	21.19	1	294	1	297	8.0e-21	95	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647646191	569	32.34	38	569	12	525	3.0e-101	362	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647646193	202	20.92	8	202	4	199	1.0e-12	66.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647646194	226	37.82	11	203	7	195	3.0e-27	115	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
647646195	118	34.48	4	118	16	130	1.0e-17	81.5	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
647646196	530	34.43	4	518	3	483	2.0e-74	273	COG3333	TctA family transporter	504
647646198	293	26.09	2	291	22	315	2.0e-28	120	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
647646199	265	28.14	26	223	5	199	2.0e-19	90	COG2188	DNA-binding transcriptional regulator, GntR family	236
647646200	567	34.16	13	561	16	536	4.0e-99	355	COG0405	Gamma-glutamyltranspeptidase	539
647646202	768	23.92	467	762	18	309	6.0e-30	126	COG0668	Small-conductance mechanosensitive channel	316
647646204	337	29.32	1	337	14	367	8.0e-47	181	COG2021	Homoserine acetyltransferase	368
647646205	317	33.81	27	306	1	279	2.0e-54	206	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
647646206	173	28.99	4	172	4	172	3.0e-16	78.1	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647646207	427	46.58	45	424	1	379	1.0e-85	310	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647646208	346	31.64	4	338	8	332	9.0e-59	220	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647646209	488	52.34	1	488	1	488	0.0e+00	536	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
647646210	351	41.23	1	346	11	368	2.0e-84	305	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
647646211	304	35.87	3	301	1	308	4.0e-50	191	COG0524	Sugar or nucleoside kinase, ribokinase family	311
647646212	132	43.75	22	130	18	129	2.0e-25	108	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
647646216	266	25.13	69	259	36	221	6.0e-12	65	COG2801	Transposase InsO and inactivated derivatives	232
647646218	461	31.25	14	157	14	151	3.0e-20	93.6	COG3666	Transposase	161
647646225	63	41.3	3	44	10	55	7.0e-07	45.4	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
647646226	340	26.77	18	339	16	394	9.0e-34	137	COG1530	Ribonuclease G or E	487
647646227	192	45.5	1	186	3	190	2.0e-56	211	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
647646228	72	69.44	1	72	1	72	5.0e-24	102	COG0361	Translation initiation factor IF-1	75
647646229	291	30.82	1	273	3	262	1.0e-26	114	COG0388	Predicted amidohydrolase	274
647646230	321	28.04	7	275	2	268	3.0e-25	109	COG0583	DNA-binding transcriptional regulator, LysR family	297
647646231	239	44.49	1	228	12	246	9.0e-65	240	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
647646232	171	38	1	150	1	148	7.0e-28	116	COG2847	Copper(I)-binding protein	151
647646234	100	60.27	1	73	1	73	3.0e-21	93.4	COG0227	Ribosomal protein L28	77
647646235	231	22.32	1	221	3	222	2.0e-26	112	COG1183	Phosphatidylserine synthase	234
647646236	151	45.24	26	146	45	168	7.0e-27	113	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
647646237	971	42.93	9	970	1	929	0.0e+00	1034	COG0060	Isoleucyl-tRNA synthetase	933
647646238	344	35.05	49	335	48	338	1.0e-48	187	COG3768	Uncharacterized membrane protein YcjF, UPF0283 family	350
647646239	149	21.53	1	127	11	154	5.0e-06	43.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
647646240	470	43.38	26	470	17	466	1.0e-122	433	COG3106	Predicted ATPase, YcjX-like family	467
647646241	256	45.63	1	252	1	247	2.0e-75	275	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
647646242	475	51.5	8	470	4	468	0.0e+00	580	COG0362	6-phosphogluconate dehydrogenase	473
647646243	152	22.92	15	150	2	145	6.0e-07	46.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
647646244	493	32.86	63	488	4	322	7.0e-50	191	COG0306	Phosphate/sulfate permease	326
647646245	332	28.3	7	314	3	297	4.0e-41	162	COG1893	Ketopantoate reductase	307
647646246	301	49.84	1	300	6	310	2.0e-109	389	COG0078	Ornithine carbamoyltransferase	310
647646247	407	54.05	21	400	17	395	0.0e+00	495	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
647646249	191	42.63	1	190	1	169	2.0e-34	138	COG5352	Uncharacterized protein	169
647646250	194	32.6	10	189	5	184	2.0e-24	105	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
647646251	420	39.39	1	412	15	438	2.0e-91	329	COG0612	Predicted Zn-dependent peptidase	438
647646252	462	29.61	1	459	1	411	6.0e-95	341	COG0498	Threonine synthase	411
647646253	225	34.48	2	220	11	242	2.0e-36	145	COG3346	Cytochrome oxidase assembly protein ShyY1	252
647646254	267	39.52	58	267	10	208	8.0e-40	157	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
647646255	191	57.14	14	173	18	178	2.0e-58	218	COG3175	Cytochrome c oxidase assembly protein Cox11	195
647646256	329	44.48	16	322	1	301	1.0e-79	289	COG0109	Polyprenyltransferase (heme O synthase)	304
647646257	288	29.23	31	287	17	238	3.0e-46	178	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
647646258	492	40.35	46	490	15	454	3.0e-108	386	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
647646259	347	38.11	3	345	22	349	2.0e-71	262	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
647646260	881	49.15	1	578	1	570	0.0e+00	617	COG0550	DNA topoisomerase IA	570
647646262	231	57.14	1	217	1	216	4.0e-79	287	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
647646263	208	62.14	3	207	6	211	1.0e-73	269	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
647646268	486	33.7	28	484	11	453	1.0e-83	304	COG4964	Flp pilus assembly protein, secretin CpaC	455
647646269	231	29.14	22	190	16	189	2.0e-22	99.5	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
647646270	412	25.08	93	401	42	341	3.0e-30	126	COG4963	Flp pilus assembly protein, ATPase CpaE	366
647646271	479	56.42	80	437	1	353	7.0e-122	431	COG4962	Pilus assembly protein, ATPase of CpaF family	355
647646272	320	26.58	6	320	1	309	1.0e-37	150	COG4965	Flp pilus assembly protein TadB	309
647646273	308	29.76	59	308	69	319	2.0e-20	93	COG2064	Pilus assembly protein TadC	320
647646276	164	27.61	7	161	3	163	6.0e-06	44.1	COG4960	Flp pilus assembly protein, protease CpaA	168
647646278	252	31.92	1	249	11	269	4.0e-31	128	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
647646279	816	32.48	2	794	6	798	0.0e+00	633	COG1201	Lhr-like helicase	814
647646280	276	32.46	64	245	2	191	4.0e-29	121	COG1407	Metallophosphoesterase superfamily enzyme	235
647646281	139	25.9	1	139	3	139	2.0e-18	84.7	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
647646282	300	56.75	4	292	1	282	6.0e-108	384	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
647646283	562	65.34	9	562	1	554	0.0e+00	892	COG2759	Formyltetrahydrofolate synthetase	554
647646284	126	30.43	1	115	9	115	5.0e-07	46.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
647646287	635	54.49	5	599	1	596	0.0e+00	694	COG0465	ATP-dependent Zn proteases	596
647646289	277	25.12	60	269	49	256	4.0e-21	95.5	COG1729	Periplasmic TolA-binding protein (function unknown)	262
647646290	171	32.42	1	165	6	187	3.0e-26	111	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
647646291	430	38.66	1	428	2	424	2.0e-84	306	COG0823	Periplasmic component of the Tol biopolymer transport system	425
647646293	159	41.18	14	149	3	137	5.0e-36	143	COG0848	Biopolymer transport protein ExbD	137
647646294	231	45.12	19	231	1	215	3.0e-46	178	COG0811	Biopolymer transport protein ExbB/TolQ	216
647646295	132	39.2	1	124	4	128	8.0e-31	126	COG0824	Acyl-CoA thioesterase FadM	137
647646296	339	63.11	5	332	6	331	0.0e+00	493	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
647646297	221	40.09	1	217	1	200	8.0e-49	186	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
647646298	168	52.94	5	156	1	153	5.0e-46	176	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
647646300	72	36.54	21	72	12	63	1.0e-05	41.5	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
647646302	290	33.07	37	288	49	299	2.0e-51	196	COG2264	Ribosomal protein L11 methylase PrmA	300
647646304	731	46.9	20	730	11	730	0.0e+00	700	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
647646305	217	49.35	1	217	8	238	7.0e-67	247	COG0176	Transaldolase	239
647646307	255	21.74	29	255	7	218	6.0e-11	61.5	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
647646308	314	36.45	11	312	2	300	5.0e-64	238	COG4974	Site-specific recombinase XerD	300
647646309	323	48.11	1	316	2	316	3.0e-84	305	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
647646310	804	35.16	4	803	48	845	0.0e+00	601	COG1643	HrpA-like RNA helicase	845
647646312	230	31.28	8	225	11	235	8.0e-28	117	COG5343	Anti-sigma-K factor RskA	240
647646313	180	34.3	9	178	5	175	8.0e-25	106	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
647646315	399	23.16	7	391	4	385	2.0e-34	140	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647646316	257	47.84	1	254	1	255	3.0e-67	248	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
647646318	383	41.88	9	380	5	386	9.0e-84	304	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647646319	521	34.29	1	514	8	522	4.0e-80	292	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647646320	392	40.57	9	391	1	386	4.0e-76	278	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647646323	513	16.27	32	496	4	461	5.0e-09	56.3	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
647646324	2993	26.51	1570	2178	19	636	3.0e-63	239	COG1020	Non-ribosomal peptide synthetase component F	642
647646325	316	25.38	1	304	8	328	2.0e-26	113	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647646326	164	23.08	12	154	15	154	7.0e-08	50.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647646327	429	36.98	46	428	3	379	1.0e-59	224	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647646328	388	27.98	34	372	11	370	6.0e-17	82.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
647646329	1029	37.62	9	1008	3	1009	0.0e+00	812	COG0841	Multidrug efflux pump subunit AcrB	1009
647646330	402	19.7	1	397	21	420	6.0e-31	128	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
647646332	333	34.06	16	326	6	321	8.0e-56	210	COG2144	Selenophosphate synthetase-related protein	324
647646334	374	21.17	13	364	1	339	3.0e-42	166	COG2516	Biotin synthase-related protein, radical SAM superfamily	339
647646335	321	25.93	3	295	1	270	5.0e-32	132	COG0388	Predicted amidohydrolase	274
647646337	453	30.38	12	446	2	450	4.0e-71	262	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
647646339	368	59.52	4	368	1	372	0.0e+00	481	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
647646341	315	50	53	311	1	262	8.0e-86	310	COG0159	Tryptophan synthase alpha chain	265
647646342	388	37.17	7	388	1	359	1.0e-96	346	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
647646343	186	33.8	1	71	25	93	7.0e-08	50.6	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
647646344	238	47.54	1	181	2	184	4.0e-65	241	COG0193	Peptidyl-tRNA hydrolase	190
647646345	344	43.27	3	341	7	346	6.0e-80	291	COG4427	Uncharacterized protein	350
647646346	391	24.85	96	391	66	389	2.0e-29	123	COG1680	CubicO group peptidase, beta-lactamase class C family	390
647646347	113	62.26	3	108	19	124	6.0e-36	142	COG3651	Uncharacterized conserved protein, DUF2237 family	125
647646349	408	71.68	11	402	1	390	0.0e+00	701	COG0133	Tryptophan synthase beta chain	396
647646351	643	18.88	1	579	5	617	4.0e-27	116	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
647646352	456	33.93	27	456	3	436	1.0e-121	429	COG0621	tRNA A37 methylthiotransferase MiaB	437
647646355	126	26.27	7	123	12	126	3.0e-06	44.1	COG3011	Predicted thiol-disulfide oxidoreductase YuxK, DCC family	137
647646356	206	36.89	3	202	14	219	3.0e-32	131	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
647646359	288	28.37	8	286	3	283	6.0e-46	177	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
647646361	203	50.63	126	202	6	84	1.0e-23	103	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
647646362	198	32.83	4	189	22	219	3.0e-25	108	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
647646363	148	32.67	6	132	27	176	2.0e-16	78.9	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
647646364	347	43.03	23	343	19	344	5.0e-74	271	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
647646365	522	52.38	13	514	1	501	0.0e+00	634	COG3845	ABC-type uncharacterized transport system, ATPase component	501
647646366	376	41.57	1	355	5	350	7.0e-73	267	COG4603	ABC-type uncharacterized transport system, permease component	356
647646367	322	52.66	4	322	5	304	9.0e-74	270	COG1079	ABC-type uncharacterized transport system, permease component	304
647646368	302	31.69	8	291	1	257	1.0e-15	77.4	COG0730	Uncharacterized membrane protein YfcA	258
647646370	232	33.61	2	224	7	242	3.0e-39	155	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647646372	211	31.47	1	187	1	196	6.0e-29	120	COG3916	N-acyl-L-homoserine lactone synthetase	209
647646373	239	36.92	173	237	1	65	6.0e-10	58.1	COG2771	DNA-binding transcriptional regulator, CsgD family	65
647646374	426	29.58	35	408	1	326	3.0e-50	192	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647646376	655	44.76	8	491	71	548	0.0e+00	480	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
647646377	106	25.2	1	106	5	127	1.0e-05	41.9	COG2916	DNA-binding protein H-NS	128
647646378	236	53.02	1	232	2	233	3.0e-88	317	COG0813	Purine-nucleoside phosphorylase	236
647646379	280	36.7	1	265	8	256	2.0e-53	203	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
647646380	550	65.01	7	548	5	546	0.0e+00	773	COG3573	Predicted oxidoreductase	552
647646382	248	51.93	15	246	1	230	1.0e-84	306	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
647646385	601	52.85	7	578	3	561	0.0e+00	618	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
647646386	123	26.09	9	122	3	117	6.0e-11	59.8	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
647646387	127	37.4	9	127	3	125	2.0e-12	64.6	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
647646388	320	44.37	4	313	1	308	2.0e-101	362	COG0039	Malate/lactate dehydrogenase	313
647646390	250	25.98	3	249	2	255	3.0e-06	45.8	COG0730	Uncharacterized membrane protein YfcA	258
647646391	285	42.35	10	281	1	280	1.0e-57	217	COG2301	Citrate lyase beta subunit	283
647646393	345	31.29	8	152	13	157	2.0e-13	70.1	COG2030	Acyl dehydratase	159
647646394	397	58.9	1	397	1	386	0.0e+00	521	COG0045	Succinyl-CoA synthetase, beta subunit	387
647646397	285	66.78	2	284	12	291	2.0e-114	405	COG0074	Succinyl-CoA synthetase, alpha subunit	293
647646398	987	52.55	7	984	1	906	0.0e+00	1267	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
647646399	507	50.12	105	506	2	404	1.0e-111	397	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
647646400	127	30.43	12	126	9	123	2.0e-09	54.5	COG3686	Uncharacterized conserved protein, MAPEG superfamily	125
647646401	131	29.13	5	131	1	125	6.0e-12	63	COG3686	Uncharacterized conserved protein, MAPEG superfamily	125
647646402	462	49.78	1	452	2	454	0.0e+00	513	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
647646403	241	23.01	9	240	3	235	7.0e-21	94.6	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
647646404	301	21.38	16	301	11	295	8.0e-20	91.4	COG2177	Cell division protein FtsX	297
647646405	225	46.58	1	218	1	215	9.0e-68	250	COG2884	ABC-type ATPase involved in cell division	223
647646408	421	46.48	1	394	1	394	1.0e-114	406	COG0019	Diaminopimelate decarboxylase	394
647646411	463	56.92	6	460	2	455	0.0e+00	621	COG0165	Argininosuccinate lyase	459
647646412	185	33.33	39	160	8	127	1.0e-10	59.5	COG0526	Thiol-disulfide isomerase or thioredoxin	127
647646415	174	47.85	12	174	37	199	5.0e-45	174	COG5631	Predicted transcription regulator, contains HTH domain, MarR family	199
647646416	213	50.75	12	211	8	208	4.0e-56	211	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
647646417	599	38.02	8	599	4	571	0.0e+00	556	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
647646418	291	34.25	3	288	1	292	4.0e-41	161	COG2971	BadF-type ATPase, related to human N-acetylglucosamine kinase	301
647646419	375	43.32	6	366	3	366	1.0e-97	350	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
647646420	898	35.52	389	894	5	521	4.0e-94	339	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647646421	231	42.31	5	229	33	264	3.0e-64	238	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
647646422	366	40	17	365	8	349	4.0e-97	348	COG3435	Gentisate 1,2-dioxygenase	351
647646428	628	33.9	6	357	1	341	1.0e-60	228	COG3276	Selenocysteine-specific translation elongation factor	447
647646429	463	43.86	78	454	18	389	7.0e-77	281	COG1921	Seryl-tRNA(Sec) selenium transferase	395
647646430	212	24.88	1	208	8	220	3.0e-21	95.3	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
647646431	308	34.94	1	302	2	305	2.0e-75	275	COG4286	Uncharacterized protein, UPF0160 family	306
647646434	458	38.56	2	457	14	467	3.0e-122	432	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647646436	315	36.46	28	307	4	284	7.0e-48	184	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
647646437	360	41.11	8	360	8	364	2.0e-78	286	COG3490	Uncharacterized protein	366
647646438	328	23.77	1	328	16	359	7.0e-29	121	COG3489	Predicted periplasmic lipoprotein	359
647646439	517	58.19	44	517	7	481	0.0e+00	618	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
647646441	420	63.94	6	420	33	446	0.0e+00	528	COG3487	Uncharacterized iron-regulated protein	446
647646443	365	27.74	16	316	39	324	1.0e-26	114	COG4927	Predicted choloylglycine hydrolase	336
647646444	363	29.89	101	363	45	312	7.0e-32	131	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
647646446	473	38.07	283	473	11	200	2.0e-39	157	COG1573	Uracil-DNA glycosylase	202
647646447	411	58.72	5	411	2	404	0.0e+00	547	COG4277	Predicted DNA-binding protein with the Helix-hairpin-helix motif	404
647646448	123	24.03	1	123	1	129	4.0e-07	46.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
647646449	365	29.86	157	357	7	214	2.0e-29	123	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
647646451	681	35.04	1	366	1	363	2.0e-88	320	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
647646452	227	25.58	17	187	7	178	6.0e-15	74.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647646453	332	33.75	8	321	9	319	4.0e-43	168	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
647646455	502	42.05	1	495	4	493	5.0e-119	421	COG3333	TctA family transporter	504
647646456	283	33.57	7	281	5	280	4.0e-51	195	COG0169	Shikimate 5-dehydrogenase	283
647646457	628	38.63	267	626	2	361	5.0e-98	352	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
647646458	434	24.2	1	431	5	435	1.0e-41	164	COG4097	Predicted ferric reductase	438
647646462	202	49.21	14	202	9	199	5.0e-38	150	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
647646463	302	44.1	46	273	56	269	4.0e-58	218	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
647646465	871	55.04	5	853	1	781	0.0e+00	943	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
647646467	229	42.24	1	228	9	234	2.0e-44	172	COG0284	Orotidine-5'-phosphate decarboxylase	240
647646469	392	46	11	353	2	351	5.0e-87	314	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
647646470	286	36.9	7	275	7	261	8.0e-54	203	COG3741	N-formylglutamate amidohydrolase	272
647646473	290	26.27	45	254	1	200	1.0e-24	106	COG0625	Glutathione S-transferase	211
647646476	299	38.56	75	299	4	236	1.0e-40	160	COG0412	Dienelactone hydrolase	236
647646477	556	34.67	20	556	9	536	2.0e-71	264	COG1178	ABC-type Fe3+ transport system, permease component	540
647646478	408	30.67	45	395	53	422	2.0e-46	180	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
647646479	283	52.46	18	261	1	237	6.0e-80	290	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
647646480	455	19.58	42	420	1	359	2.0e-17	84	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
647646481	358	31.88	32	350	11	314	5.0e-39	155	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
647646482	329	27.38	5	328	3	297	2.0e-33	136	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
647646483	273	45.24	18	269	2	250	6.0e-85	307	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
647646484	656	33.11	13	617	17	611	2.0e-117	417	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
647646485	636	24.54	254	515	71	335	1.0e-17	84.8	COG0642	Signal transduction histidine kinase	336
647646486	233	37.39	4	229	1	228	3.0e-43	168	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647646488	252	33.05	14	250	13	251	1.0e-27	117	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647646489	401	25	6	400	2	409	4.0e-28	119	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647646490	922	39.29	5	917	6	940	0.0e+00	863	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
647646491	217	25.38	1	187	2	185	2.0e-13	69.1	COG0406	Broad specificity phosphatase PhoE	208
647646492	206	34.67	2	196	1	197	8.0e-30	123	COG0625	Glutathione S-transferase	211
647646494	245	33.33	15	206	13	214	3.0e-32	132	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647646496	414	20.87	10	412	16	441	1.0e-22	101	COG2211	Na+/melibiose symporter or related transporter	467
647646497	253	34.3	9	245	11	249	4.0e-37	148	COG3496	Uncharacterized conserved protein, DUF1365 family	261
647646498	439	41.37	18	435	9	428	8.0e-105	374	COG2907	Predicted NAD/FAD-binding protein	447
647646499	413	27.81	20	394	27	413	9.0e-55	207	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
647646500	613	42.88	13	613	2	638	0.0e+00	613	COG0323	DNA mismatch repair ATPase MutL	638
647646501	406	63.82	10	405	8	404	0.0e+00	521	COG3748	Uncharacterized membrane protein	407
647646502	474	39.34	8	459	2	444	4.0e-78	285	COG2233	Xanthine/uracil permease	451
647646503	162	48.1	5	160	4	161	8.0e-45	173	COG3194	Ureidoglycolate hydrolase (allantoin degradation)	168
647646504	271	52.22	1	270	1	264	5.0e-89	321	COG3257	Uncharacterized protein, possibly involved in glyoxylate utilization	264
647646505	479	52.87	306	479	1	171	3.0e-55	210	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
647646507	119	60.17	2	119	7	124	1.0e-41	162	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
647646508	340	32.82	69	329	2	227	1.0e-51	196	COG0274	Deoxyribose-phosphate aldolase	228
647646509	779	46.45	33	481	1	463	1.0e-130	461	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647646510	438	30.88	7	432	1	434	2.0e-68	253	COG0612	Predicted Zn-dependent peptidase	438
647646511	447	32.29	27	437	16	425	4.0e-69	255	COG0612	Predicted Zn-dependent peptidase	438
647646513	165	31.29	2	148	11	153	1.0e-20	92.6	COG0597	Lipoprotein signal peptidase	167
647646514	528	64.38	6	528	1	515	0.0e+00	753	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
647646515	582	31.25	26	562	40	564	1.0e-73	271	COG5360	Uncharacterized conserved protein, heparinase superfamily	566
647646516	423	37.01	93	421	3	353	6.0e-66	245	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
647646519	256	55.91	1	254	14	266	2.0e-79	289	COG0289	Dihydrodipicolinate reductase	266
647646520	136	31.25	1	110	10	118	1.0e-15	76	COG0858	Ribosome-binding factor A	118
647646521	242	50.63	1	239	11	247	1.0e-66	246	COG3698	Uncharacterized protein YigE, DUF2233 family	250
647646523	277	38.32	2	275	32	271	3.0e-58	219	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
647646524	169	38.65	2	164	3	163	3.0e-34	137	COG4333	Uncharacterized protein	167
647646526	89	58.43	1	89	1	89	7.0e-26	108	COG0184	Ribosomal protein S15P/S13E	89
647646528	330	27.61	14	329	87	411	3.0e-48	186	COG2124	Cytochrome P450	411
647646532	353	38.82	71	321	22	265	2.0e-52	199	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
647646537	202	23.46	17	185	10	184	5.0e-20	91.2	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
647646539	976	29.99	9	649	1	615	5.0e-105	376	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
647646540	197	43.6	1	164	8	157	4.0e-35	141	COG0437	Fe-S-cluster-containing dehydrogenase component	203
647646541	404	26.94	160	402	4	218	6.0e-33	135	COG2864	Cytochrome b subunit of formate dehydrogenase	218
647646543	234	43.61	2	228	1	227	1.0e-48	186	COG4662	ABC-type tungstate transport system, periplasmic component	227
647646545	266	45.7	9	264	19	273	5.0e-73	267	COG2998	ABC-type tungstate transport system, permease component	280
647646546	238	19.26	1	233	3	245	8.0e-22	97.4	COG3306	Glycosyltransferase involved in LPS biosynthesis, GR25 family	255
647646547	217	36.1	1	199	1	194	3.0e-53	201	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
647646548	479	44.37	7	473	3	465	0.0e+00	461	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647646550	215	40.99	2	215	68	289	8.0e-57	213	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
647646552	306	48.97	17	306	4	292	5.0e-81	294	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
647646553	814	37.56	419	814	1	379	3.0e-92	333	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
647646554	296	30.59	1	291	7	299	1.0e-46	180	COG2040	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)	300
647646555	814	33.83	427	814	1	379	8.0e-78	285	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
647646557	207	26.92	1	202	1	208	7.0e-16	77.6	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
647646559	127	42.5	1	120	37	154	4.0e-33	133	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
647646560	390	42.86	1	390	1	392	6.0e-76	278	COG0183	Acetyl-CoA acetyltransferase	392
647646561	113	32.11	1	107	3	111	1.0e-08	51.9	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
647646562	150	26.87	12	145	7	137	5.0e-13	66.9	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
647646563	525	38.52	2	525	1	539	0.0e+00	464	COG0405	Gamma-glutamyltranspeptidase	539
647646564	108	59.41	6	106	13	113	5.0e-32	129	COG3785	Heat shock protein HspQ	116
647646565	293	31.17	3	293	1	308	7.0e-24	104	COG0679	Predicted permease	311
647646567	201	21.94	1	190	2	197	2.0e-21	96.2	COG2834	Outer membrane lipoprotein-sorting protein	211
647646568	958	28.69	15	957	2	856	0.0e+00	495	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
647646569	404	28.82	18	401	5	389	9.0e-61	227	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
647646570	442	37.39	1	441	1	467	2.0e-84	306	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
647646571	408	38.94	4	397	2	387	3.0e-71	262	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647646572	50	56	1	50	5	54	8.0e-12	62.2	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
647646573	214	41.21	7	201	8	205	6.0e-37	147	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
647646574	304	35.97	1	303	11	304	2.0e-62	232	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
647646575	290	36.84	33	290	3	261	3.0e-70	258	COG0708	Exonuclease III	261
647646576	219	42.15	2	218	7	226	3.0e-49	188	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647646577	362	56.32	173	362	6	193	7.0e-60	224	COG0807	GTP cyclohydrolase II	193
647646578	164	36.9	1	164	54	216	9.0e-32	129	COG3786	L,D-peptidoglycan transpeptidase YkuD, ErfK/YbiS/YcfS/YnhG family	217
647646579	228	47.35	11	227	4	228	4.0e-68	251	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
647646583	848	46.98	1	848	2	814	0.0e+00	937	COG0495	Leucyl-tRNA synthetase	814
647646584	153	21.38	2	149	10	168	2.0e-09	55	COG5468	Predicted secreted (periplasmic) protein	172
647646585	332	20.91	4	308	3	314	1.0e-15	77.7	COG1466	DNA polymerase III, delta subunit	334
647646586	196	27.32	10	192	10	202	5.0e-21	94.1	COG0625	Glutathione S-transferase	211
647646587	400	33.82	8	398	3	408	2.0e-88	319	COG2081	Predicted flavoprotein YhiN	408
647646588	210	40.48	1	200	6	214	7.0e-32	130	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647646589	241	36.32	1	220	10	231	1.0e-40	159	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647646591	448	35.67	6	448	2	454	1.0e-78	287	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
647646592	258	33.21	5	255	4	259	6.0e-43	167	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
647646594	409	31.61	7	384	19	401	9.0e-51	194	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
647646595	330	41.3	2	329	3	335	8.0e-73	267	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
647646596	370	49.07	1	369	4	372	3.0e-117	415	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
647646597	227	25.68	52	226	71	244	4.0e-14	71.8	COG1651	Protein-disulfide isomerase	244
647646598	169	24.42	4	169	18	181	1.0e-12	66.2	COG5389	Uncharacterized protein	181
647646599	354	43.7	1	354	2	341	1.0e-96	346	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
647646601	129	24.03	1	128	5	130	2.0e-06	44.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
647646602	366	33.22	13	291	16	298	1.0e-57	217	COG0863	DNA modification methylase	302
647646603	205	51.87	19	201	2	188	4.0e-59	221	COG0164	Ribonuclease HII	199
647646607	258	55.69	1	255	1	255	2.0e-85	309	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
647646608	391	18.88	25	361	35	368	5.0e-08	52.5	COG2814	Predicted arabinose efflux permease, MFS family	394
647646609	340	53.41	2	332	1	333	2.0e-117	415	COG0136	Aspartate-semialdehyde dehydrogenase	334
647646611	216	26.44	11	213	7	202	1.0e-37	149	COG0288	Carbonic anhydrase	207
647646613	460	41.06	27	458	32	484	3.0e-115	408	COG0260	Leucyl aminopeptidase	485
647646614	251	24.29	62	226	8	183	4.0e-12	65.4	COG0791	Cell wall-associated hydrolase, NlpC family	197
647646616	145	31.58	1	129	1	132	3.0e-20	90.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
647646617	436	54.35	14	435	15	437	0.0e+00	518	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
647646618	205	18.63	1	204	1	197	2.0e-09	55.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647646619	324	32.58	78	254	1	176	2.0e-31	129	COG1633	Rubrerythrin	176
647646620	309	32.15	1	308	2	309	2.0e-27	116	COG0679	Predicted permease	311
647646621	277	36.57	1	277	7	315	2.0e-62	232	COG0627	S-formylglutathione hydrolase FrmB	316
647646622	149	43.62	1	149	1	148	7.0e-40	156	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
647646623	225	22.16	20	200	2	195	4.0e-15	74.9	COG1011	FMN phosphatase YigB, HAD superfamily	229
647646624	306	36.19	46	301	53	317	5.0e-47	181	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
647646627	434	19.47	56	424	38	386	6.0e-14	72.5	COG2814	Predicted arabinose efflux permease, MFS family	394
647646628	352	42.37	5	352	12	363	1.0e-103	369	COG1485	Predicted ATPase	367
647646630	424	44.34	1	423	2	421	1.0e-109	390	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
647646631	314	53.9	1	291	1	293	8.0e-109	386	COG0777	Acetyl-CoA carboxylase beta subunit	294
647646634	788	47.82	11	576	10	572	0.0e+00	661	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
647646637	449	43.32	8	401	1	398	4.0e-94	338	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
647646638	373	21.36	17	371	48	419	7.0e-25	108	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
647646639	515	52.25	12	515	1	508	0.0e+00	614	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
647646640	59	32	2	51	11	59	4.0e-07	46.5	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
647646642	931	52.03	322	931	1	593	0.0e+00	723	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
647646644	255	42.35	4	253	5	255	2.0e-64	239	COG3622	Hydroxypyruvate isomerase	260
647646645	196	53.61	10	194	7	200	8.0e-63	233	COG3816	Uncharacterized protein	205
647646646	335	41.99	7	328	4	325	7.0e-63	234	COG0714	MoxR-like ATPase	329
647646650	675	44.27	27	675	19	732	0.0e+00	591	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
647646651	1794	37.48	296	1794	112	1620	0.0e+00	925	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
647646653	252	39.22	1	252	1	252	3.0e-56	212	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
647646654	681	44.69	4	592	5	584	0.0e+00	619	COG0514	Superfamily II DNA helicase RecQ	590
647646657	457	34.67	6	454	12	433	4.0e-81	295	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
647646658	309	47.69	51	308	27	276	2.0e-75	276	COG3770	Murein endopeptidase	284
647646659	278	29.39	20	278	64	339	1.0e-20	93.9	COG4246	Uncharacterized protein	340
647646661	245	44.35	1	244	1	247	5.0e-59	221	COG1338	Flagellar biosynthetic protein FliP	248
647646663	422	32.93	2	399	6	417	1.0e-65	244	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
647646664	161	20.5	3	160	2	158	9.0e-09	53.3	COG1580	Flagellar basal body-associated protein FliL	159
647646666	289	34.74	1	285	3	265	2.0e-51	196	COG1291	Flagellar motor component MotA	266
647646668	266	24.62	69	259	36	221	1.0e-12	67.3	COG2801	Transposase InsO and inactivated derivatives	232
647646671	323	30.75	1	321	15	333	2.0e-61	229	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
647646672	401	39.8	5	396	4	385	3.0e-86	312	COG3214	Uncharacterized conserved protein YcaQ, contains winged helix DNA-binding domain	400
647646673	414	26.29	1	412	3	382	2.0e-32	133	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647646674	329	19.58	1	329	1	330	8.0e-38	151	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647646675	174	19.76	1	166	2	165	2.0e-07	48.8	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647646676	441	29.71	59	434	3	376	2.0e-60	226	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647646677	245	33.78	7	228	1	219	5.0e-29	121	COG2049	Allophanate hydrolase subunit 1	223
647646678	342	36.36	5	304	1	306	4.0e-59	222	COG1984	Allophanate hydrolase subunit 2	314
647646679	260	48.39	4	251	1	248	2.0e-74	272	COG1540	Lactam utilization protein B (function unknown)	252
647646686	298	41.37	22	289	1	270	2.0e-76	279	COG0253	Diaminopimelate epimerase	272
647646687	418	37.67	6	416	7	432	1.0e-117	416	COG0621	tRNA A37 methylthiotransferase MiaB	437
647646689	219	31.55	6	206	7	212	1.0e-28	119	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
647646690	282	33.73	37	278	30	250	6.0e-33	134	COG2857	Cytochrome c1	250
647646691	447	46.4	9	408	1	372	7.0e-88	318	COG1290	Cytochrome b subunit of the bc complex	381
647646692	186	36.7	1	186	1	166	3.0e-36	144	COG0723	Rieske Fe-S protein	177
647646693	203	25.59	1	203	1	206	3.0e-18	85.6	COG0625	Glutathione S-transferase	211
647646694	207	34.76	1	202	1	202	3.0e-35	142	COG2808	Predicted FMN-binding regulatory protein PaiB	209
647646695	144	37.93	1	140	10	151	2.0e-28	117	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
647646696	642	55.87	7	633	2	623	0.0e+00	849	COG1154	Deoxyxylulose-5-phosphate synthase	627
647646697	301	41.72	43	301	30	322	4.0e-51	195	COG0142	Geranylgeranyl pyrophosphate synthase	322
647646698	80	37.88	4	69	5	70	1.0e-09	55	COG1722	Exonuclease VII small subunit	81
647646699	230	39.3	4	230	2	228	8.0e-51	193	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647646700	207	21.97	62	192	1	126	1.0e-09	56.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
647646701	289	37.68	9	289	1	282	1.0e-63	236	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
647646703	325	22.03	12	302	7	283	3.0e-08	52.9	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
647646704	366	56.3	4	357	3	355	0.0e+00	502	COG0082	Chorismate synthase	369
647646705	325	50.76	2	325	7	336	1.0e-95	343	COG4143	ABC-type thiamine transport system, periplasmic component	336
647646706	499	33.47	27	494	55	533	4.0e-56	212	COG1178	ABC-type Fe3+ transport system, permease component	540
647646707	230	48.92	1	230	1	231	2.0e-65	242	COG3840	ABC-type thiamine transport system, ATPase component	231
647646708	284	23.39	9	270	8	296	3.0e-16	79.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647646709	417	18.48	22	388	18	363	3.0e-22	99.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647646710	259	41.76	1	256	4	257	5.0e-51	194	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647646711	671	31.07	2	599	1	597	1.0e-81	298	COG1042	Acyl-CoA synthetase (NDP forming)	598
647646712	386	37.63	1	386	1	392	2.0e-82	299	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647646713	242	27.15	1	221	3	219	4.0e-38	151	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
647646714	605	47.82	8	601	1	583	0.0e+00	618	COG1001	Adenine deaminase	584
647646715	487	23.94	210	465	1	233	1.0e-41	164	COG0775	Nucleoside phosphorylase	234
647646716	91	47.78	1	90	2	91	2.0e-15	74	COG0776	Bacterial nucleoid DNA-binding protein	94
647646718	182	43.31	32	182	7	161	2.0e-44	171	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
647646719	149	61.76	4	137	1	136	1.0e-56	212	COG0229	Peptide methionine sulfoxide reductase MsrB	140
647646720	154	47.44	1	150	19	174	2.0e-53	201	COG0225	Peptide methionine sulfoxide reductase MsrA	174
647646721	668	30.15	1	582	1	590	3.0e-75	276	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
647646722	342	44.12	4	338	2	337	3.0e-88	318	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
647646723	221	32.67	4	202	3	201	1.0e-33	136	COG0625	Glutathione S-transferase	211
647646727	1510	56.24	717	1201	2	484	0.0e+00	606	COG0069	Glutamate synthase domain 2	485
647646728	462	42.89	10	449	2	446	2.0e-118	419	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
647646729	261	35.63	2	260	11	268	3.0e-44	171	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
647646730	327	29.25	3	254	1	242	4.0e-21	95.7	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
647646733	155	36.36	5	100	11	108	3.0e-19	88	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
647646734	354	29.21	1	290	2	266	3.0e-48	185	COG1018	Ferredoxin-NADP reductase	266
647646735	674	26.51	4	511	1	472	9.0e-62	232	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647646736	256	25.88	20	249	6	257	3.0e-15	75.4	COG3327	DNA-binding transcriptional regulator PaaX (phenylacetic acid degradation)	291
647646738	309	56.19	2	193	9	202	1.0e-56	213	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
647646740	164	32.34	8	164	4	166	1.0e-17	82.3	COG1934	Lipopolysaccharide export system protein LptA	173
647646741	252	64.02	15	251	5	243	8.0e-101	359	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
647646742	188	33.04	1	110	1	110	3.0e-21	94.9	COG1544	Ribosome-associated translation inhibitor RaiA	110
647646743	154	32.89	2	151	1	152	8.0e-26	109	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
647646744	475	21.94	1	210	1	230	1.0e-05	45	COG4424	LPS sulfotransferase NodH	250
647646748	327	49.69	3	324	2	325	2.0e-126	445	COG1087	UDP-glucose 4-epimerase	329
647646749	297	52.07	3	291	2	289	2.0e-108	385	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
647646751	266	36.09	1	265	2	247	3.0e-53	202	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
647646752	265	49.61	11	257	13	263	9.0e-68	250	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
647646753	257	17.72	3	239	18	249	4.0e-09	55.2	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
647646754	200	39.15	8	194	16	194	1.0e-34	139	COG3145	Alkylated DNA repair dioxygenase AlkB	194
647646755	635	61.63	1	600	4	579	0.0e+00	685	COG0443	Molecular chaperone DnaK (HSP70)	579
647646756	384	55.35	1	381	1	371	6.0e-127	447	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
647646757	252	37.61	35	252	7	224	3.0e-61	228	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
647646759	520	26.64	128	368	65	317	2.0e-19	91.3	COG0226	ABC-type phosphate transport system, periplasmic component	318
647646761	716	28.27	15	458	2	458	4.0e-50	193	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
647646762	187	21.55	10	184	7	185	4.0e-06	44.6	COG3009	Uncharacterized lipoprotein YmbA	190
647646763	694	28.32	1	508	7	498	2.0e-74	273	COG3008	Paraquat-inducible protein B	553
647646766	186	39.78	8	182	4	188	4.0e-27	114	COG0693	Putative intracellular protease/amidase	188
647646767	440	46.53	1	439	10	445	0.0e+00	509	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
647646768	323	32.62	28	299	40	311	1.0e-35	144	COG4927	Predicted choloylglycine hydrolase	336
647646770	909	29.19	283	902	6	550	3.0e-112	400	COG1982	Arginine/lysine/ornithine decarboxylase	557
647646771	372	29.18	6	241	5	254	1.0e-29	124	COG0388	Predicted amidohydrolase	274
647646773	319	46.25	1	317	1	318	8.0e-96	343	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
647646774	538	29.8	36	493	14	484	1.0e-108	387	COG0069	Glutamate synthase domain 2	485
647646775	439	49.54	9	433	16	446	0.0e+00	473	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
647646778	573	28.5	355	564	7	216	2.0e-31	130	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
647646779	185	34.76	7	164	18	181	1.0e-29	122	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
647646780	269	27.19	145	255	7	119	3.0e-10	59.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
647646781	101	24.21	7	101	10	104	2.0e-07	47.2	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
647646783	303	29.62	11	289	20	303	2.0e-37	149	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
647646784	283	26.64	30	280	6	262	4.0e-34	138	COG2116	Formate/nitrite transporter FocA, FNT family	265
647646786	426	31.91	8	422	7	407	1.0e-65	244	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647646787	423	21.41	1	423	1	420	3.0e-38	153	COG0443	Molecular chaperone DnaK (HSP70)	579
647646788	492	33.77	10	492	26	554	2.0e-81	296	COG0747	ABC-type transport system, periplasmic component	556
647646789	344	27.46	4	287	31	317	5.0e-52	198	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
647646791	315	45.25	1	314	1	316	1.0e-83	303	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647646792	271	49.25	2	267	21	287	1.0e-61	229	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647646793	533	53.1	1	526	4	534	0.0e+00	627	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
647646794	153	32.28	1	122	1	115	1.0e-12	66.1	COG5628	Predicted acetyltransferase	143
647646795	248	42.52	1	246	1	250	9.0e-46	176	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647646796	331	35.59	1	330	9	347	4.0e-57	215	COG3191	L-aminopeptidase/D-esterase	348
647646797	268	27.56	1	262	2	282	3.0e-15	75.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647646799	152	44.36	10	139	14	131	7.0e-20	90	COG3474	Cytochrome c2	135
647646800	215	32.86	4	209	1	204	1.0e-28	119	COG0625	Glutathione S-transferase	211
647646801	234	41.56	4	232	36	264	5.0e-61	227	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
647646802	748	47.17	5	744	2	710	0.0e+00	691	COG2217	Cation transport ATPase	713
647646803	502	28.02	5	493	1	486	4.0e-56	212	COG3898	Uncharacterized membrane-anchored protein	531
647646804	486	25.31	83	479	19	415	5.0e-06	46.3	COG4223	Uncharacterized conserved protein	422
647646805	234	18.78	3	225	1	242	1.0e-12	66.6	COG1587	Uroporphyrinogen-III synthase	248
647646806	372	51	12	359	1	338	6.0e-116	411	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
647646807	317	46.34	1	317	2	329	1.0e-90	326	COG0240	Glycerol-3-phosphate dehydrogenase	329
647646808	90	39.13	1	89	1	92	2.0e-18	84.2	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
647646809	139	47.74	1	139	2	154	4.0e-43	167	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
647646811	252	21.27	34	240	26	214	6.0e-08	51.4	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647646812	374	29.73	53	374	63	393	1.0e-57	217	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
647646813	451	25.43	12	349	34	320	8.0e-33	135	COG1858	Cytochrome c peroxidase	364
647646815	386	31.45	61	377	1	310	2.0e-48	186	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
647646816	335	46.43	1	327	8	341	2.0e-90	325	COG4213	ABC-type xylose transport system, periplasmic component	341
647646817	437	41.25	17	433	10	393	2.0e-97	350	COG4214	ABC-type xylose transport system, permease component	394
647646819	477	39.76	1	476	5	497	5.0e-112	398	COG1070	Sugar (pentulose or hexulose) kinase	502
647646820	432	66.59	1	432	2	438	0.0e+00	699	COG2115	Xylose isomerase	438
647646821	515	25.25	24	223	10	201	8.0e-17	82.4	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
647646822	712	37.25	8	690	1	640	0.0e+00	594	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
647646823	159	32.5	34	153	7	126	1.0e-14	72.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
647646824	265	37.7	22	264	5	218	3.0e-44	172	COG1878	Kynurenine formamidase	218
647646825	371	20.93	3	371	22	403	2.0e-27	116	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
647646826	386	39.84	21	386	21	392	3.0e-95	342	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
647646827	258	32.2	19	240	4	234	3.0e-34	138	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647646828	468	54.49	7	460	1	420	0.0e+00	618	COG0499	S-adenosylhomocysteine hydrolase	420
647646829	197	26.11	15	189	1	179	2.0e-22	98.9	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
647646830	161	22.9	11	138	11	141	2.0e-08	51.8	COG1247	L-amino acid N-acyltransferase YncA	169
647646831	183	68.75	9	183	7	182	1.0e-63	236	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
647646832	205	35.68	3	198	4	200	2.0e-32	132	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
647646833	436	22.03	71	415	1	330	1.0e-19	91.4	COG0642	Signal transduction histidine kinase	336
647646835	158	40.67	8	156	1	149	7.0e-33	133	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
647646836	334	41.94	11	309	2	338	2.0e-63	236	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
647646838	987	31.28	8	705	1	697	1.0e-77	285	COG3893	Inactivated superfamily I helicase	697
647646839	1125	26.74	15	1104	12	1139	0.0e+00	504	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
647646842	185	66.48	9	183	2	175	5.0e-66	243	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
647646843	435	61.43	1	435	1	444	0.0e+00	635	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
647646845	193	30.26	1	193	2	182	1.0e-22	99.6	COG2840	DNA-nicking endonuclease, Smr domain	184
647646846	335	34.09	7	322	24	365	4.0e-70	258	COG2821	Membrane-bound lytic murein transglycosylase	373
647646847	219	24.07	1	219	44	279	6.0e-27	114	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
647646848	136	35.2	1	125	33	148	4.0e-18	83.7	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
647646849	163	40.88	5	163	1	156	2.0e-34	138	COG1952	Preprotein translocase subunit SecB	157
647646850	228	38.26	1	228	13	239	5.0e-43	167	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
647646851	196	36.36	1	195	2	199	1.0e-43	169	COG0237	Dephospho-CoA kinase	201
647646852	277	41.37	1	275	1	278	7.0e-79	287	COG0169	Shikimate 5-dehydrogenase	283
647646853	199	34.69	1	195	1	188	1.0e-39	156	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
647646854	149	45.58	3	148	2	147	3.0e-29	121	COG1981	Uncharacterized membrane protein	149
647646855	423	69.36	3	423	1	420	0.0e+00	673	COG1158	Transcription termination factor Rho	422
647646856	428	42.38	1	428	4	454	1.0e-118	420	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
647646857	623	57.58	5	621	3	621	0.0e+00	884	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
647646858	266	43.31	10	261	2	251	3.0e-58	218	COG1192	Cellulose biosynthesis protein BcsQ	259
647646859	278	38.55	14	271	1	240	1.0e-31	130	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
647646860	385	42.75	1	385	26	412	4.0e-103	368	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
647646861	203	45.79	9	197	3	186	3.0e-55	207	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
647646862	237	53.85	1	233	8	226	1.0e-67	249	COG0689	Ribonuclease PH	230
647646863	354	39.07	10	351	3	341	8.0e-88	317	COG1420	Transcriptional regulator of heat shock response	346
647646864	187	38.67	3	182	12	190	1.0e-30	126	COG0576	Molecular chaperone GrpE (heat shock protein)	193
647646865	898	46.99	22	894	5	843	0.0e+00	870	COG0249	DNA mismatch repair ATPase MutS	843
647646867	752	57.58	9	427	19	426	0.0e+00	574	COG0281	Malic enzyme	432
647646868	290	33.01	1	287	1	306	9.0e-38	150	COG0524	Sugar or nucleoside kinase, ribokinase family	311
647646869	212	49.33	20	167	3	152	3.0e-52	198	COG0225	Peptide methionine sulfoxide reductase MsrA	174
647646870	302	29.47	20	297	3	280	1.0e-46	180	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
647646873	406	59.71	1	405	1	403	0.0e+00	605	COG0137	Argininosuccinate synthase	403
647646874	410	43.66	10	340	13	347	6.0e-98	351	COG1171	Threonine dehydratase	347
647646876	408	27.6	127	403	102	367	2.0e-32	133	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
647646878	328	31.73	10	316	4	281	7.0e-62	231	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
647646879	184	16.34	20	163	6	153	3.0e-06	45	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
647646881	613	35.86	25	604	7	567	3.0e-117	416	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647646882	609	34.56	35	601	15	567	6.0e-108	385	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647646883	401	29.74	2	386	16	431	9.0e-63	234	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
647646887	216	25.65	23	216	2	229	1.0e-15	76.8	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
647646889	328	42.46	1	325	6	320	8.0e-98	350	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
647646891	242	37.72	11	238	8	223	3.0e-38	152	COG1040	Predicted amidophosphoribosyltransferases	225
647646892	85	61.25	2	80	1	80	3.0e-23	100	COG0695	Glutaredoxin	80
647646893	276	37.05	1	273	3	265	6.0e-48	184	COG0388	Predicted amidohydrolase	274
647646894	145	24.56	26	139	11	123	2.0e-09	54.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
647646895	248	52.67	6	248	10	243	1.0e-81	296	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
647646896	323	23.43	25	321	3	282	1.0e-18	87.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647646898	537	54.64	166	358	3	190	6.0e-51	195	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
647646899	206	47.06	14	98	7	89	1.0e-19	89.6	COG2740	Predicted RNA-binding protein YlxR, DUF448 family	95
647646900	829	58.46	324	829	1	508	0.0e+00	630	COG0532	Translation initiation factor IF-2, a GTPase	509
647646901	265	27.49	3	239	2	243	2.0e-20	92.7	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
647646902	306	27.3	5	303	4	300	1.0e-33	137	COG1597	Diacylglycerol kinase family enzyme	301
647646905	408	47.79	7	408	1	404	4.0e-119	421	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
647646906	282	23.89	1	275	20	311	9.0e-15	74.4	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
647646907	938	54.65	49	928	1	820	0.0e+00	1039	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
647646908	178	41.21	2	178	56	225	2.0e-37	148	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
647646910	223	38.38	28	222	41	224	3.0e-41	161	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
647646914	448	30.56	92	270	37	206	5.0e-18	85.9	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
647646915	316	25.59	1	294	3	291	7.0e-24	104	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
647646919	530	43.6	1	530	6	538	0.0e+00	506	COG2303	Choline dehydrogenase or related flavoprotein	542
647646921	163	36.71	1	153	3	160	1.0e-23	102	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
647646922	172	35.06	17	164	20	171	3.0e-24	104	COG1443	Isopentenyldiphosphate isomerase	185
647646923	383	38.23	1	380	2	394	1.0e-82	300	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
647646924	257	36.47	1	252	3	254	8.0e-45	174	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647646926	816	26.35	328	789	59	509	2.0e-07	51.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
647646927	238	23.18	5	237	32	261	6.0e-25	107	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
647646929	218	33.48	1	217	24	243	2.0e-51	195	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
647646930	452	29.33	114	452	38	371	1.0e-54	207	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
647646931	306	20.68	1	266	1	246	8.0e-11	61.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
647646934	835	24.49	200	438	5	240	3.0e-19	91	COG1216	Glycosyltransferase, GT2 family	305
647646935	231	21.68	53	195	35	176	5.0e-13	68.4	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
647646937	338	34.46	1	336	1	348	1.0e-60	226	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
647646940	107	34.41	4	95	40	131	1.0e-15	74.8	COG1917	Cupin domain protein related to quercetin dioxygenase	131
647646941	299	31.63	7	296	2	288	1.0e-36	146	COG0583	DNA-binding transcriptional regulator, LysR family	297
647646945	250	31.22	2	235	57	291	1.0e-48	186	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
647646946	499	44.23	21	490	1	469	0.0e+00	464	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647646947	434	24.42	22	397	2	371	4.0e-28	119	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647646948	504	25.5	8	495	2	469	1.0e-57	217	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647646949	241	35.11	4	228	1	210	9.0e-44	170	COG0684	Regulator of RNase E activity RraA	210
647646950	549	44.65	1	536	30	574	0.0e+00	629	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
647646952	438	35	5	437	6	445	6.0e-77	281	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
647646953	173	20.61	1	160	1	159	4.0e-08	51	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
647646954	340	25.51	5	336	16	346	2.0e-31	130	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
647646955	236	31.72	12	236	5	229	1.0e-29	123	COG1802	DNA-binding transcriptional regulator, GntR family	230
647646956	284	48.02	21	269	2	253	2.0e-86	312	COG0024	Methionine aminopeptidase	255
647646960	311	37.86	14	291	2	275	6.0e-61	227	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
647646961	201	34.07	2	183	1	168	1.0e-25	109	COG0431	NAD(P)H-dependent FMN reductase	184
647646962	143	32.31	1	128	6	134	2.0e-08	51.9	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
647646963	301	32	4	298	3	295	6.0e-42	164	COG0583	DNA-binding transcriptional regulator, LysR family	297
647646964	804	62.74	8	579	3	575	0.0e+00	880	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
647646965	206	30.05	3	203	1	203	8.0e-14	70.7	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
647646966	365	34.9	4	354	1	358	1.0e-72	267	COG1195	Recombinational DNA repair ATPase RecF	363
647646967	372	42.2	1	372	1	364	1.0e-84	306	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
647646968	454	45.96	5	450	1	408	2.0e-116	412	COG0593	Chromosomal replication initiation ATPase DnaA	408
647646969	87	54.65	1	86	1	86	4.0e-15	73	COG0268	Ribosomal protein S20	88
647646970	258	43.19	1	253	2	256	1.0e-58	220	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647646971	283	49.12	1	283	1	273	2.0e-93	335	COG0266	Formamidopyrimidine-DNA glycosylase	273
647646972	259	51.46	22	259	1	238	2.0e-81	295	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
647646973	510	39.57	1	509	1	511	3.0e-123	435	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
647646975	395	48.32	5	388	3	388	1.0e-118	420	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
647646976	347	32.86	5	344	1	350	1.0e-68	253	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
647646978	531	48.77	1	324	2	323	3.0e-96	346	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
647646979	379	29.43	7	374	1	362	2.0e-94	339	COG1932	Phosphoserine aminotransferase	365
647646980	322	46.19	105	314	3	212	1.0e-52	200	COG0560	Phosphoserine phosphatase	212
647646981	326	37.95	1	323	7	338	1.0e-60	226	COG4448	L-asparaginase II	339
647646983	391	51.1	22	380	1	349	5.0e-118	417	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
647646986	280	35.71	59	278	4	205	2.0e-39	155	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
647646987	305	50.54	34	305	2	270	1.0e-85	309	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
647646988	84	50	4	83	1	82	1.0e-06	44.7	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
647646993	368	33.16	4	368	26	408	5.0e-67	248	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647646994	140	33.08	17	140	24	152	1.0e-16	79.2	COG2153	Predicted N-acyltransferase, GNAT family	155
647646995	198	33.01	2	193	5	202	3.0e-22	98.5	COG3222	Uncharacterized conserved protein, glycosyltransferase A (GT-A) superfamily, DUF2064 family	211
647646996	753	38.63	1	711	1	706	0.0e+00	565	COG0557	Exoribonuclease R	706
647646997	404	47.48	2	334	10	343	1.0e-79	290	COG2951	Membrane-bound lytic murein transglycosylase B	343
647646998	392	35.29	117	388	3	267	8.0e-54	204	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
647646999	561	45.65	332	561	60	287	5.0e-67	249	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
647647000	371	20.69	1	368	3	362	6.0e-28	118	COG0687	Spermidine/putrescine-binding periplasmic protein	363
647647001	366	45.3	6	366	1	352	7.0e-111	393	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
647647002	396	30.95	7	396	1	383	2.0e-74	273	COG0006	Xaa-Pro aminopeptidase	384
647647003	384	31.16	1	383	10	406	3.0e-57	215	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647647004	476	41.85	10	456	2	449	0.0e+00	501	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
647647005	226	33.33	7	226	2	222	5.0e-33	134	COG1802	DNA-binding transcriptional regulator, GntR family	230
647647006	361	42.06	4	361	14	363	1.0e-84	307	COG0687	Spermidine/putrescine-binding periplasmic protein	363
647647007	375	47.51	15	375	3	352	3.0e-120	425	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
647647008	293	51.43	8	287	12	280	3.0e-69	255	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
647647009	273	50.76	2	262	7	267	1.0e-61	229	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
647647010	442	25.4	35	404	2	368	1.0e-39	157	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647647011	439	54.65	1	419	1	414	0.0e+00	546	COG1004	UDP-glucose 6-dehydrogenase	414
647647015	270	22.38	1	267	10	286	1.0e-15	77.4	COG1344	Flagellin and related hook-associated protein FlgL	360
647647018	445	43.21	1	438	3	440	1.0e-120	427	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
647647019	115	27.19	7	115	20	132	5.0e-11	59.9	COG1815	Flagellar basal body rod protein FlgB	133
647647020	130	33.82	3	129	2	137	1.0e-25	108	COG1558	Flagellar basal body rod protein FlgC	137
647647022	89	35.96	2	88	1	89	4.0e-09	52.8	COG1987	Flagellar biosynthesis protein FliQ	89
647647023	237	31.7	1	236	1	265	1.0e-42	166	COG4786	Flagellar basal body rod protein FlgG	265
647647024	261	47.17	1	261	2	264	9.0e-71	260	COG4786	Flagellar basal body rod protein FlgG	265
647647026	242	33.47	1	239	4	230	3.0e-44	172	COG2063	Flagellar basal body L-ring protein FlgH	230
647647029	361	33.24	4	361	3	358	7.0e-79	287	COG1377	Flagellar biosynthesis protein FlhB	363
647647031	677	38.64	3	675	27	693	0.0e+00	585	COG1298	Flagellar biosynthesis pathway, component FlhA	696
647647033	301	19.64	9	287	8	283	6.0e-07	48.6	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
647647034	442	28.54	22	432	2	376	2.0e-71	263	COG1488	Nicotinic acid phosphoribosyltransferase	405
647647035	201	34.5	1	192	3	185	3.0e-31	128	COG1335	Nicotinamidase-related amidase	205
647647036	299	50.17	2	299	5	303	1.0e-111	396	COG1054	Predicted sulfurtransferase	308
647647037	280	24.54	13	280	1	242	5.0e-29	121	COG1360	Flagellar motor protein MotB	244
647647038	432	30.87	6	432	4	423	3.0e-52	199	COG1749	Flagellar hook protein FlgE	423
647647039	490	23.16	7	490	1	550	6.0e-44	172	COG1256	Flagellar hook-associated protein FlgK	552
647647040	334	17.61	9	334	7	357	1.0e-08	54.3	COG1344	Flagellin and related hook-associated protein FlgL	360
647647041	367	50.55	5	366	4	364	2.0e-106	379	COG1706	Flagellar basal body P-ring protein FlgI	365
647647044	140	28.36	1	124	1	126	1.0e-07	49.1	COG3607	Predicted lactoylglutathione lyase	133
647647046	249	37.55	3	245	1	250	2.0e-29	122	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647647047	308	31.58	9	306	6	299	1.0e-39	156	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
647647048	404	37.87	7	399	1	393	9.0e-98	350	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
647647049	288	32.97	3	276	2	276	1.0e-54	206	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
647647050	259	51.19	3	254	2	252	2.0e-79	289	COG1540	Lactam utilization protein B (function unknown)	252
647647051	271	50.23	41	256	5	221	2.0e-57	216	COG2049	Allophanate hydrolase subunit 1	223
647647052	354	41.1	3	308	1	304	5.0e-76	278	COG1984	Allophanate hydrolase subunit 2	314
647647053	223	37.38	1	210	10	223	8.0e-30	124	COG1802	DNA-binding transcriptional regulator, GntR family	230
647647054	323	42.9	1	303	4	311	7.0e-64	237	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
647647055	427	23.06	16	427	1	408	1.0e-18	87.9	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647647056	211	32.24	1	211	12	225	1.0e-28	119	COG1802	DNA-binding transcriptional regulator, GntR family	230
647647057	392	34.55	15	389	2	380	7.0e-72	264	COG0006	Xaa-Pro aminopeptidase	384
647647058	137	61.76	1	136	2	137	4.0e-55	206	COG3565	Predicted dioxygenase of extradiol dioxygenase family	138
647647059	340	31.76	1	339	43	379	8.0e-56	211	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647647061	185	22.02	19	185	4	167	2.0e-09	55.7	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647647062	313	26.01	1	313	16	332	1.0e-36	147	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647647067	632	43.08	299	617	2	316	3.0e-88	319	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
647647068	315	20.67	15	298	37	334	4.0e-11	62.7	COG4188	Predicted dienelactone hydrolase	365
647647069	314	23.59	11	307	1	289	2.0e-18	87	COG0583	DNA-binding transcriptional regulator, LysR family	297
647647070	422	42.89	23	422	4	396	4.0e-96	345	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
647647071	529	37	13	499	1	484	9.0e-85	308	COG2272	Carboxylesterase type B	491
647647072	297	40.28	2	211	1	213	8.0e-33	134	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647647073	896	33.33	52	574	12	526	1.0e-74	275	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647647074	182	40	1	180	1	180	6.0e-47	180	COG4681	Uncharacterized conserved protein YaeQ, suppresses RfaH defect	181
647647076	357	20.77	39	314	6	289	5.0e-08	52.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
647647077	368	54.99	1	367	1	348	9.0e-120	423	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
647647080	201	52.74	1	201	1	189	2.0e-74	271	COG0066	3-isopropylmalate dehydratase small subunit	191
647647082	469	58.09	2	467	1	422	0.0e+00	628	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
647647086	227	26.58	6	224	9	228	2.0e-27	116	COG1018	Ferredoxin-NADP reductase	266
647647087	122	48.04	10	111	3	104	7.0e-32	129	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
647647088	156	40.74	1	155	1	155	2.0e-38	151	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
647647090	237	38.57	17	234	5	227	9.0e-42	163	COG3821	Uncharacterized membrane protein	234
647647091	482	37.45	20	469	1	459	2.0e-85	309	COG0277	FAD/FMN-containing dehydrogenase	459
647647092	372	25.94	4	368	39	455	8.0e-32	131	COG0277	FAD/FMN-containing dehydrogenase	459
647647094	463	25.92	15	443	1	387	1.0e-68	254	COG0247	Fe-S oxidoreductase	388
647647096	159	30.34	1	141	4	145	1.0e-24	105	COG0071	Molecular chaperone IbpA, HSP20 family	146
647647097	406	42.93	7	406	67	459	1.0e-94	340	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
647647098	490	44.47	20	487	1	466	0.0e+00	507	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647647100	396	29.16	11	388	2	378	5.0e-45	175	COG0006	Xaa-Pro aminopeptidase	384
647647101	361	26.67	155	359	8	215	1.0e-29	124	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
647647104	126	36.52	7	121	1	110	3.0e-22	97.4	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
647647108	184	50	34	183	3	151	1.0e-48	186	COG0691	tmRNA-binding protein	153
647647109	284	45.13	8	284	12	285	4.0e-82	298	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
647647110	394	46.84	1	392	1	395	0.0e+00	468	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
647647111	434	38.35	39	433	5	407	8.0e-85	307	COG0004	Ammonia channel protein AmtB	409
647647112	112	62.5	1	112	1	112	5.0e-36	142	COG0347	Nitrogen regulatory protein PII	112
647647113	732	37.32	59	732	10	661	0.0e+00	485	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
647647114	197	22.87	7	185	5	192	5.0e-19	87.6	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
647647115	246	35.94	20	231	16	228	3.0e-33	135	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
647647116	152	31.97	6	152	1	129	1.0e-17	82.3	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
647647117	253	30.04	11	252	8	252	3.0e-30	125	COG0584	Glycerophosphoryl diester phosphodiesterase	257
647647118	413	52.45	23	407	7	386	1.0e-126	446	COG3146	Predicted N-acyltransferase	387
647647119	101	46.53	1	101	2	100	2.0e-24	103	COG2154	Pterin-4a-carbinolamine dehydratase	101
647647120	162	43.37	1	162	1	165	2.0e-46	178	COG0678	Peroxiredoxin	165
647647122	183	48.4	1	181	2	184	1.0e-47	182	COG0742	16S rRNA G966 N2-methylase RsmD	187
647647123	253	36.28	16	239	5	222	1.0e-36	146	COG1183	Phosphatidylserine synthase	234
647647124	271	49	13	260	3	253	3.0e-82	298	COG0024	Methionine aminopeptidase	255
647647125	234	48.71	1	232	1	228	2.0e-69	255	COG1489	DNA-binding protein, stimulates sugar fermentation	235
647647126	239	36.36	5	236	3	244	1.0e-55	209	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
647647128	189	27.84	11	182	3	177	2.0e-19	89.1	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
647647129	312	36.17	169	309	55	190	5.0e-20	92.2	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
647647130	301	33.22	3	298	2	296	1.0e-45	176	COG0583	DNA-binding transcriptional regulator, LysR family	297
647647131	313	25.69	30	313	35	322	4.0e-42	165	COG0598	Mg2+ and Co2+ transporter CorA	322
647647133	690	43.37	18	370	2	362	2.0e-101	364	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
647647134	163	27.44	3	160	1	154	2.0e-10	58.5	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
647647135	327	60.49	31	315	2	287	1.0e-128	453	COG0788	Formyltetrahydrofolate hydrolase	287
647647137	329	28.8	6	315	2	295	3.0e-36	145	COG0524	Sugar or nucleoside kinase, ribokinase family	311
647647138	214	53.43	10	213	6	209	2.0e-77	281	COG0177	Endonuclease III	211
647647140	293	35.76	130	289	4	168	9.0e-35	140	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
647647141	221	41.49	34	220	4	190	2.0e-33	135	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
647647142	180	36.42	5	174	2	167	1.0e-26	113	COG0431	NAD(P)H-dependent FMN reductase	184
647647143	138	25.18	13	133	3	136	9.0e-09	52.9	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
647647144	260	40.68	7	260	12	271	5.0e-48	184	COG3777	Hydroxyacyl-ACP dehydratase HTD2, hotdog domain	273
647647145	343	25.26	1	343	4	381	1.0e-24	107	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647647146	223	38.56	4	222	7	241	3.0e-51	195	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
647647147	657	28.57	343	632	2	288	6.0e-22	99.5	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
647647148	291	51.37	1	289	4	295	1.0e-90	326	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
647647149	387	45.29	1	387	2	391	6.0e-105	374	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
647647150	290	22.3	1	288	1	281	7.0e-18	84.9	COG3302	DMSO reductase anchor subunit	281
647647151	221	40.11	1	186	27	195	5.0e-43	167	COG0437	Fe-S-cluster-containing dehydrogenase component	203
647647153	368	41.62	6	361	3	396	1.0e-98	353	COG0282	Acetate kinase	396
647647154	592	33.04	2	563	1	533	2.0e-109	390	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
647647155	487	33.54	14	484	1	454	7.0e-96	344	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
647647157	463	34.57	11	461	3	444	1.0e-109	390	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
647647158	717	32.59	2	486	37	513	3.0e-96	346	COG0513	Superfamily II DNA and RNA helicase	513
647647159	170	31.62	39	154	8	124	2.0e-10	58.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
647647160	304	28.21	25	295	32	304	5.0e-33	135	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
647647161	523	30.19	13	489	9	511	2.0e-82	300	COG0405	Gamma-glutamyltranspeptidase	539
647647162	244	33.99	47	243	70	257	3.0e-17	82	COG4544	Uncharacterized conserved protein	260
647647163	477	22.5	72	430	31	350	5.0e-13	69.6	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
647647164	1103	35.29	23	1096	1	1103	0.0e+00	975	COG0587	DNA polymerase III, alpha subunit	1139
647647166	209	50.76	8	203	14	202	3.0e-61	228	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
647647167	211	38.16	1	211	2	229	1.0e-46	179	COG0830	Urease accessory protein UreF	229
647647168	150	43.85	24	150	25	154	3.0e-27	114	COG2371	Urease accessory protein UreE	155
647647169	569	75.7	2	569	1	568	0.0e+00	1025	COG0804	Urease alpha subunit	568
647647170	101	67.33	1	101	1	101	5.0e-43	165	COG0832	Urease beta subunit	106
647647172	100	72	1	100	1	100	1.0e-43	168	COG0831	Urease gamma subunit	100
647647173	260	33.96	2	258	8	269	1.0e-50	193	COG0829	Urease accessory protein UreH	269
647647174	437	37.44	1	437	2	447	9.0e-88	317	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
647647175	209	30.81	22	205	4	182	8.0e-24	103	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
647647176	345	24.71	6	330	1	334	3.0e-31	129	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
647647177	294	35.48	171	294	1	124	1.0e-19	90.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647647178	392	25	4	384	1	379	3.0e-53	202	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647647179	326	32.63	1	325	1	325	2.0e-45	176	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647647180	197	24.08	1	190	4	188	2.0e-13	68.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647647184	461	31.25	14	157	14	151	3.0e-20	93.6	COG3666	Transposase	161
647647185	298	28.38	1	275	3	274	4.0e-13	68.7	COG4974	Site-specific recombinase XerD	300
647647190	229	30.09	11	226	11	223	3.0e-39	155	COG1451	Predicted metal-dependent hydrolase	223
647647191	216	28.11	1	215	4	219	2.0e-23	102	COG1802	DNA-binding transcriptional regulator, GntR family	230
647647192	320	58.73	1	315	1	314	9.0e-123	433	COG0825	Acetyl-CoA carboxylase alpha subunit	317
647647193	199	25.85	1	196	1	205	1.0e-17	83	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
647647194	319	37.75	18	319	3	281	5.0e-63	234	COG2301	Citrate lyase beta subunit	283
647647195	391	40.71	82	388	32	335	4.0e-71	262	COG3367	Uncharacterized conserved protein, NAD-dependent epimerase/dehydratase family	339
647647196	321	31.55	1	321	4	355	1.0e-45	176	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
647647197	286	34.36	1	285	1	284	8.0e-59	220	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
647647199	103	58.7	1	92	6	96	2.0e-27	113	COG3492	Uncharacterized protein	104
647647200	245	48.18	1	241	8	251	5.0e-67	247	COG3931	Predicted N-formylglutamate amidohydrolase	263
647647201	460	45.59	1	447	22	475	0.0e+00	507	COG0469	Pyruvate kinase	477
647647203	66	46.88	1	64	1	64	2.0e-09	54.5	COG0291	Ribosomal protein L35	65
647647204	121	62.5	1	120	1	118	1.0e-38	151	COG0292	Ribosomal protein L20	118
647647205	401	25.19	18	401	10	389	2.0e-11	64.1	COG2814	Predicted arabinose efflux permease, MFS family	394
647647207	357	51.32	4	340	9	335	3.0e-116	411	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
647647209	265	23.91	1	248	8	277	7.0e-14	71.2	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
647647210	799	39.42	159	798	13	650	0.0e+00	535	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
647647212	536	45.22	1	533	6	535	4.0e-125	442	COG2303	Choline dehydrogenase or related flavoprotein	542
647647213	235	34.12	20	225	1	200	5.0e-35	141	COG0625	Glutathione S-transferase	211
647647214	143	44.06	1	143	3	130	1.0e-30	125	COG1970	Large-conductance mechanosensitive channel	130
647647215	372	62.97	1	370	1	370	0.0e+00	507	COG0686	Alanine dehydrogenase	371
647647216	153	44.74	1	152	4	154	1.0e-36	145	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647647217	504	39.92	1	500	8	527	5.0e-116	411	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647647219	438	36.32	52	431	1	376	3.0e-79	289	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647647220	182	23.23	16	170	4	155	9.0e-14	70	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647647221	314	27.83	1	300	2	305	3.0e-42	165	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647647222	230	36.84	19	226	16	223	5.0e-31	127	COG1802	DNA-binding transcriptional regulator, GntR family	230
647647224	238	27.92	4	198	17	213	6.0e-28	117	COG5590	Ubiquinone biosynthesis protein COQ9	229
647647225	249	34.22	12	227	2	226	1.0e-45	176	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
647647227	342	42.73	19	340	1	326	5.0e-78	284	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647647228	325	43.38	5	324	4	326	5.0e-73	268	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647647229	200	37.3	8	184	45	229	7.0e-38	150	COG3719	Ribonuclease I	249
647647230	249	50.66	1	222	7	230	2.0e-61	229	COG3820	Uncharacterized protein	230
647647231	366	20.7	16	319	6	302	2.0e-25	110	COG3021	Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily	309
647647233	390	34.3	28	390	24	394	9.0e-66	244	COG0019	Diaminopimelate decarboxylase	394
647647234	616	46.84	4	615	1	585	0.0e+00	792	COG0173	Aspartyl-tRNA synthetase	585
647647236	301	26.8	117	265	35	187	2.0e-17	83.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
647647239	244	22.63	4	234	2	244	6.0e-20	91.1	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
647647240	190	23.59	5	182	2	195	2.0e-13	69.2	COG0778	Nitroreductase	207
647647241	368	44.7	38	336	22	318	2.0e-72	266	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
647647243	307	23.02	9	288	2	281	9.0e-11	61.3	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
647647244	356	49.21	24	336	6	314	2.0e-102	366	COG0180	Tryptophanyl-tRNA synthetase	314
647647246	530	36.84	1	526	4	518	5.0e-79	289	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
647647247	928	37.99	50	915	1	858	0.0e+00	732	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
647647248	394	22.65	48	363	10	340	1.0e-09	58.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
647647249	309	41.3	28	303	2	274	2.0e-72	265	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
647647250	125	36.28	13	123	1	113	6.0e-20	89.5	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
647647251	311	39.2	1	311	1	316	6.0e-66	244	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
647647252	305	29.58	1	297	1	309	1.0e-38	153	COG0657	Acetyl esterase/lipase	312
647647253	504	52.87	14	497	1	485	0.0e+00	566	COG0606	Predicted ATPase with chaperone activity	490
647647254	227	28.93	13	203	9	203	2.0e-17	82.9	COG0625	Glutathione S-transferase	211
647647255	187	29.57	1	179	8	193	4.0e-23	101	COG0406	Broad specificity phosphatase PhoE	208
647647256	277	36.1	1	273	77	339	1.0e-49	190	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
647647257	268	20.66	26	257	55	285	3.0e-18	85.8	COG3016	Uncharacterized iron-regulated protein	295
647647258	397	46.23	1	396	1	391	2.0e-105	375	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
647647259	149	48.99	1	149	3	148	3.0e-41	160	COG0756	dUTPase	148
647647260	349	49.41	95	343	1	253	1.0e-74	273	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
647647261	143	31.09	25	143	5	112	2.0e-12	65.3	COG1416	Intracellular sulfur oxidation protein, DsrE/DsrF family	112
647647262	671	44.22	1	670	3	683	0.0e+00	721	COG0339	Zn-dependent oligopeptidase	683
647647263	310	30.53	1	310	4	324	6.0e-50	191	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
647647264	379	38.42	21	379	14	374	2.0e-73	269	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
647647265	647	31.57	3	603	1	585	3.0e-112	399	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
647647267	299	29.6	9	277	5	279	6.0e-38	151	COG1792	Cell shape-determining protein MreC	284
647647268	348	62.54	7	344	1	339	1.0e-122	433	COG1077	Actin-like ATPase involved in cell morphogenesis	342
647647269	193	32.12	8	133	2	138	7.0e-10	57.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
647647270	523	50.12	8	415	1	409	9.0e-118	417	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
647647271	221	20.5	1	179	5	196	3.0e-11	62.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647647272	509	50.2	1	506	1	505	0.0e+00	629	COG3046	Uncharacterized protein related to deoxyribodipyrimidine photolyase	505
647647273	116	28.43	1	99	1	102	2.0e-15	74.2	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
647647274	460	37.12	170	301	8	139	2.0e-17	83.8	COG4642	Uncharacterized conserved protein	139
647647275	552	39.86	260	541	1	268	1.0e-65	244	COG0171	NH3-dependent NAD+ synthetase	268
647647276	441	37.28	3	434	11	457	3.0e-105	375	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
647647277	465	29.2	26	430	28	437	3.0e-42	166	COG0534	Na+-driven multidrug efflux pump	455
647647278	381	42.49	7	381	1	376	2.0e-92	332	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
647647279	119	52.89	1	119	9	129	4.0e-36	143	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
647647280	947	58.15	452	915	6	496	0.0e+00	699	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
647647281	287	34.14	25	272	11	250	4.0e-43	168	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
647647282	842	35.24	5	840	6	828	0.0e+00	530	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
647647283	222	55.8	1	222	2	225	8.0e-73	266	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
647647284	215	30.52	24	213	11	216	2.0e-16	79.2	COG2755	Lysophospholipase L1 or related esterase	216
647647285	68	61.76	1	68	1	67	5.0e-21	92.5	COG1278	Cold shock protein, CspA family	67
647647287	440	37.53	20	438	2	450	1.0e-92	333	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
647647288	425	34.91	1	316	7	310	5.0e-78	285	COG0167	Dihydroorotate dehydrogenase	310
647647291	218	29.35	18	199	2	179	9.0e-15	73.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647647292	416	26.7	11	414	1	409	2.0e-50	193	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647647294	486	33.85	1	446	1	430	4.0e-102	365	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
647647295	260	48.63	4	258	1	246	4.0e-83	301	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
647647296	288	31.4	47	288	28	258	2.0e-36	146	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
647647297	279	30.77	21	278	1	258	7.0e-42	164	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
647647298	329	24.68	1	306	6	308	2.0e-34	140	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
647647300	68	63.24	1	68	1	67	2.0e-21	94	COG1278	Cold shock protein, CspA family	67
647647301	573	44.32	27	555	1	530	0.0e+00	572	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
647647303	661	39.17	204	654	20	450	4.0e-106	379	COG1115	Na+/alanine symporter	452
647647304	274	24	4	271	13	281	1.0e-07	50.7	COG5006	Threonine/homoserine efflux transporter RhtA	292
647647305	497	29.25	44	465	20	454	2.0e-42	167	COG2027	D-alanyl-D-alanine carboxypeptidase	470
647647307	536	37.62	21	529	1	521	0.0e+00	531	COG1384	Lysyl-tRNA synthetase, class I	521
647647309	762	16.78	189	586	83	482	3.0e-06	47.7	COG5434	Polygalacturonase	542
647647312	738	62.5	32	695	1	663	0.0e+00	1057	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
647647315	163	29.73	1	148	1	147	1.0e-23	102	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647647316	380	34.57	13	375	5	374	7.0e-72	264	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
647647317	149	25.86	35	148	32	140	4.0e-14	70.7	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
647647318	266	37.3	14	263	13	257	2.0e-44	172	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647647319	547	33.39	19	546	9	531	2.0e-109	389	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647647320	298	32.88	5	294	2	289	3.0e-33	135	COG0583	DNA-binding transcriptional regulator, LysR family	297
647647324	277	28.63	7	233	5	234	5.0e-30	124	COG0300	Short-chain dehydrogenase	265
647647327	280	40.65	6	280	4	278	9.0e-80	290	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
647647330	233	26.23	64	233	16	198	1.0e-17	83.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
647647332	168	42.07	31	166	10	154	1.0e-34	139	COG3915	Uncharacterized protein	155
647647334	786	32.37	247	523	72	335	2.0e-38	154	COG0642	Signal transduction histidine kinase	336
647647335	486	51.44	4	483	2	485	0.0e+00	565	COG1492	Cobyric acid synthase	486
647647336	181	45.98	3	176	8	180	2.0e-21	95.2	COG1268	Biotin transporter BioY	184
647647337	473	45.56	1	336	1	333	6.0e-103	367	COG0836	Mannose-1-phosphate guanylyltransferase	333
647647338	322	29.31	3	318	2	312	4.0e-41	162	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647647339	374	70.87	1	357	1	345	0.0e+00	578	COG1089	GDP-D-mannose dehydratase	345
647647340	494	28.72	18	486	2	462	6.0e-79	288	COG1109	Phosphomannomutase	464
647647341	737	63.87	4	736	3	739	0.0e+00	1029	COG2838	Monomeric isocitrate dehydrogenase	744
647647342	275	33.33	28	237	1	208	2.0e-38	153	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
647647343	262	22.35	50	219	2	164	6.0e-09	54.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647647344	191	32.43	5	182	3	186	3.0e-28	118	COG0406	Broad specificity phosphatase PhoE	208
647647345	197	44.95	1	197	1	198	3.0e-64	237	COG0353	Recombinational DNA repair protein RecR	198
647647346	114	47.52	5	105	1	101	8.0e-18	82.2	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
647647347	578	42.92	6	474	2	472	3.0e-124	439	COG2812	DNA polymerase III, gamma/tau subunits	515
647647348	245	54.33	2	242	39	291	3.0e-77	281	COG2321	Predicted metalloprotease	295
647647349	590	27.55	4	503	23	500	2.0e-59	224	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
647647350	322	38.14	14	318	1	279	1.0e-61	230	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
647647352	253	41.27	1	250	27	278	2.0e-69	255	COG0077	Prephenate dehydratase	279
647647353	169	48.48	41	169	2	132	7.0e-30	123	COG3474	Cytochrome c2	135
647647354	660	27.29	31	651	6	562	3.0e-62	233	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
647647355	362	70.33	1	361	1	364	0.0e+00	561	COG4174	ABC-type microcin C transport system, permease component YejB	364
647647356	368	55.43	1	367	2	341	7.0e-123	433	COG4239	ABC-type microcin C transport system, permease component YejE	341
647647358	530	63.36	8	528	6	529	0.0e+00	761	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
647647359	470	37	9	332	36	349	4.0e-72	265	COG1686	D-alanyl-D-alanine carboxypeptidase	389
647647360	233	25.85	4	232	3	229	2.0e-20	93	COG1011	FMN phosphatase YigB, HAD superfamily	229
647647361	113	58.16	15	112	10	107	8.0e-31	125	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
647647362	330	33.33	45	324	12	299	5.0e-53	201	COG2813	16S rRNA G1207 methylase RsmC	300
647647363	266	31.03	3	256	1	251	2.0e-34	139	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647647364	297	45.73	9	296	7	278	8.0e-91	326	COG0408	Coproporphyrinogen III oxidase	303
647647365	206	40.21	17	205	6	182	5.0e-34	137	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
647647366	297	50.52	1	290	15	303	2.0e-90	326	COG0181	Porphobilinogen deaminase	307
647647367	349	40.29	7	349	6	349	5.0e-95	341	COG0407	Uroporphyrinogen-III decarboxylase	352
647647369	362	26.63	23	354	4	329	1.0e-35	144	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647647370	337	26.51	3	329	7	330	3.0e-38	152	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647647372	439	34.56	60	437	6	375	5.0e-68	251	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647647373	604	24.31	38	464	14	428	1.0e-52	201	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647647374	512	33.14	4	510	6	518	7.0e-98	351	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
647647375	274	25	9	263	1	282	2.0e-15	76.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647647377	552	31.74	11	240	1	207	7.0e-21	95.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647647378	483	24.79	105	342	11	220	7.0e-15	75.7	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
647647380	296	28.99	118	286	1	167	6.0e-29	121	COG0703	Shikimate kinase	172
647647382	555	27.04	29	528	8	526	1.0e-56	214	COG0747	ABC-type transport system, periplasmic component	556
647647384	534	23.2	21	403	1	378	6.0e-46	179	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647647385	316	16.99	38	237	30	228	7.0e-10	58.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647647386	410	21.68	73	356	30	250	1.0e-23	104	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
647647387	453	56.88	23	451	5	427	0.0e+00	560	COG3508	Homogentisate 1,2-dioxygenase	427
647647388	149	28.57	18	142	1	126	4.0e-11	61.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
647647390	269	20.32	1	233	1	232	4.0e-18	85.2	COG1192	Cellulose biosynthesis protein BcsQ	259
647647391	73	34.67	1	73	1	72	5.0e-13	66	COG0254	Ribosomal protein L31	75
647647392	127	62.93	1	116	3	114	1.0e-37	148	COG0335	Ribosomal protein L19	115
647647393	319	33.21	20	293	8	247	2.0e-59	223	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
647647394	245	46.38	12	245	2	234	7.0e-88	316	COG0336	tRNA G37 N-methylase TrmD	240
647647396	194	35.12	16	180	6	173	4.0e-38	151	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
647647398	129	67.42	2	90	1	87	2.0e-27	114	COG0228	Ribosomal protein S16	87
647647399	98	31.52	6	96	4	95	5.0e-13	65.8	COG1605	Chorismate mutase	101
647647400	501	52.97	1	455	1	451	0.0e+00	530	COG0541	Signal recognition particle GTPase	451
647647401	199	41.92	3	190	4	201	9.0e-46	176	COG1182	FMN-dependent NADH-azoreductase	202
647647402	291	23.55	3	288	2	292	1.0e-25	110	COG0583	DNA-binding transcriptional regulator, LysR family	297
647647404	121	34.62	1	77	11	88	3.0e-08	50.6	COG0640	DNA-binding transcriptional regulator, ArsR family	110
647647405	109	28.04	3	107	6	112	7.0e-13	65.8	COG5336	FoF1-type ATP synthase assembly protein I	116
647647406	252	34.96	30	251	23	246	1.0e-37	149	COG0356	FoF1-type ATP synthase, membrane subunit a	246
647647408	183	28.38	36	182	9	156	3.0e-11	61.8	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
647647409	186	33.99	32	184	10	161	7.0e-14	70.3	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
647647410	256	36.21	1	240	1	239	2.0e-39	156	COG2186	DNA-binding transcriptional regulator, FadR family	241
647647412	1156	29.69	6	1155	1	1163	0.0e+00	527	COG1196	Chromosome segregation ATPase	1163
647647414	324	64.81	1	324	1	321	0.0e+00	505	COG0435	Glutathionyl-hydroquinone reductase	324
647647416	389	39.69	1	389	2	388	1.0e-114	406	COG1168	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	388
647647417	174	47.9	3	169	2	168	1.0e-55	209	COG0242	Peptide deformylase	168
647647418	159	46.41	1	151	1	153	7.0e-43	166	COG0242	Peptide deformylase	168
647647419	165	40.72	1	164	1	167	1.0e-38	152	COG0242	Peptide deformylase	168
647647420	304	52.61	1	299	2	307	5.0e-105	374	COG0223	Methionyl-tRNA formyltransferase	307
647647422	207	40.58	1	206	3	208	7.0e-43	167	COG2860	Uncharacterized membrane protein YeiH	209
647647423	151	59.87	1	149	1	147	9.0e-46	175	COG0328	Ribonuclease HI	154
647647426	316	57.97	5	299	1	294	1.0e-112	399	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
647647428	181	43.5	6	179	6	175	7.0e-36	143	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
647647429	184	33.88	1	182	3	160	5.0e-31	127	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
647647430	117	54.05	1	72	1	74	3.0e-12	64.2	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
647647431	716	38.59	1	702	1	700	0.0e+00	727	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
647647432	228	30.05	1	193	1	173	3.0e-27	115	COG3216	Uncharacterized conserved protein, DUF2062 family	184
647647433	250	54.55	7	248	1	242	8.0e-82	296	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
647647434	141	40.46	1	131	1	127	4.0e-37	146	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
647647435	278	28.57	1	143	1	166	3.0e-13	69.2	COG0681	Signal peptidase I	166
647647436	228	42.22	6	226	7	231	2.0e-60	225	COG0571	dsRNA-specific ribonuclease	235
647647437	302	46.49	1	298	2	298	2.0e-101	362	COG1159	GTPase Era, involved in 16S rRNA processing	298
647647438	109	35.51	3	103	2	108	7.0e-10	55.8	COG5447	Uncharacterized protein	115
647647439	241	31.49	1	225	4	237	9.0e-38	150	COG1381	Recombinational DNA repair protein (RecF pathway)	251
647647440	120	25.45	16	120	31	140	1.0e-07	48.9	COG3187	Heat shock protein HslJ	142
647647441	552	43.15	167	552	4	388	2.0e-76	280	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647647446	532	58.35	11	530	9	525	0.0e+00	733	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
647647447	233	44.64	3	233	2	228	3.0e-56	211	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647647448	572	30.99	232	571	11	328	4.0e-39	156	COG0642	Signal transduction histidine kinase	336
647647450	297	44.72	10	288	2	284	8.0e-84	303	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
647647451	126	32.03	1	126	5	132	3.0e-18	84.2	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
647647452	89	40.91	1	88	1	88	2.0e-17	81	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
647647454	291	51.89	1	290	1	291	8.0e-97	346	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
647647456	308	53.97	1	308	1	310	5.0e-84	304	COG2025	Electron transfer flavoprotein, alpha subunit	313
647647457	252	49.04	1	252	1	259	1.0e-68	253	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
647647459	190	59.38	1	190	1	184	5.0e-58	217	COG2096	Cob(I)alamin adenosyltransferase	184
647647460	275	31.94	1	187	4	193	1.0e-30	126	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647647462	773	41.88	8	768	2	739	0.0e+00	754	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
647647465	477	29.46	76	476	47	409	6.0e-49	188	COG2124	Cytochrome P450	411
647647467	362	76.67	1	295	1	298	0.0e+00	515	COG0050	Translation elongation factor EF-Tu, a GTPase	394
647647471	65	32.73	5	59	19	73	1.0e-06	44.6	COG0690	Preprotein translocase subunit SecE	73
647647472	177	48.02	1	176	1	177	1.0e-42	165	COG0250	Transcription antitermination factor NusG	178
647647473	114	59.29	1	113	27	138	9.0e-37	145	COG0080	Ribosomal protein L11	141
647647474	232	63.27	1	225	1	226	1.0e-75	276	COG0081	Ribosomal protein L1	228
647647475	244	28.28	47	188	49	188	5.0e-19	88	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
647647477	136	39.13	1	136	38	175	1.0e-24	105	COG0244	Ribosomal protein L10	175
647647478	123	56.91	1	122	2	123	5.0e-19	86.8	COG0222	Ribosomal protein L7/L12	124
647647480	1415	50.29	21	850	6	808	0.0e+00	895	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
647647481	295	22.34	1	285	2	292	8.0e-06	44.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
647647483	123	72.36	1	123	7	129	3.0e-47	180	COG0048	Ribosomal protein S12	129
647647485	156	58.78	2	149	1	148	9.0e-53	199	COG0049	Ribosomal protein S7	148
647647486	708	61.58	1	706	1	690	0.0e+00	949	COG0480	Translation elongation factor EF-G, a GTPase	697
647647487	391	77.27	1	391	1	394	0.0e+00	678	COG0050	Translation elongation factor EF-Tu, a GTPase	394
647647490	105	72.82	3	105	2	104	1.0e-38	151	COG0051	Ribosomal protein S10	104
647647491	294	53.67	3	217	1	218	5.0e-75	274	COG0087	Ribosomal protein L3	218
647647492	205	40.95	1	205	2	211	5.0e-49	187	COG0088	Ribosomal protein L4	214
647647493	98	55.32	7	98	1	94	2.0e-22	96.8	COG0089	Ribosomal protein L23	94
647647494	68	60.29	1	68	1	67	3.0e-20	90.2	COG1278	Cold shock protein, CspA family	67
647647496	230	59.19	2	224	52	274	9.0e-87	313	COG0090	Ribosomal protein L2	275
647647498	126	54.87	12	124	8	120	1.0e-28	118	COG0091	Ribosomal protein L22	120
647647499	226	61.61	3	212	1	211	2.0e-75	275	COG0092	Ribosomal protein S3	233
647647500	137	63.77	1	136	2	139	9.0e-50	188	COG0197	Ribosomal protein L16/L10AE	146
647647503	68	56.25	2	65	4	67	3.0e-11	60.3	COG0255	Ribosomal protein L29	69
647647504	79	51.9	1	79	6	84	4.0e-20	89.5	COG0186	Ribosomal protein S17	87
647647505	122	76.23	1	122	1	122	3.0e-47	180	COG0093	Ribosomal protein L14	122
647647506	103	49.06	1	102	1	104	5.0e-17	79.2	COG0198	Ribosomal protein L24	104
647647507	187	60.11	8	185	1	177	5.0e-69	253	COG0094	Ribosomal protein L5	180
647647508	101	45.9	41	101	1	61	3.0e-15	73.3	COG0199	Ribosomal protein S14	61
647647509	130	51.15	1	130	3	132	1.0e-41	162	COG0096	Ribosomal protein S8	132
647647510	177	58.19	1	176	1	176	2.0e-55	208	COG0097	Ribosomal protein L6P/L9E	178
647647511	119	53.33	4	119	7	125	9.0e-28	115	COG0256	Ribosomal protein L18	125
647647512	193	56.82	3	178	6	181	2.0e-56	211	COG0098	Ribosomal protein S5	181
647647513	62	45.45	5	59	1	55	3.0e-12	63.2	COG1841	Ribosomal protein L30/L7E	55
647647514	131	44.88	2	123	31	152	1.0e-20	91.9	COG0200	Ribosomal protein L15	152
647647515	473	48.96	33	456	10	435	1.0e-118	420	COG0201	Preprotein translocase subunit SecY	436
647647516	215	38.32	1	214	1	178	9.0e-42	163	COG0563	Adenylate kinase or related kinase	178
647647517	122	64.46	1	121	1	121	3.0e-43	167	COG0099	Ribosomal protein S13	121
647647518	129	68.22	1	129	1	129	2.0e-45	174	COG0100	Ribosomal protein S11	129
647647519	338	47.15	9	324	1	313	2.0e-95	342	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
647647520	116	64.52	1	93	24	116	1.0e-35	141	COG0203	Ribosomal protein L17	116
647647521	456	43.06	5	350	9	338	5.0e-63	235	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
647647522	435	52.53	7	434	2	435	0.0e+00	579	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
647647523	126	45.67	1	125	1	126	2.0e-15	74.8	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
647647524	349	34.37	4	323	1	289	2.0e-65	242	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
647647525	221	35.91	1	217	4	219	9.0e-38	150	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
647647526	239	42.22	1	223	27	251	2.0e-50	192	COG5387	Chaperone required for the assembly of the mitochondrial F1-ATPase	264
647647527	338	29.6	1	271	3	274	4.0e-26	112	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
647647528	404	47.28	1	404	3	397	1.0e-104	373	COG4597	ABC-type amino acid transport system, permease component	397
647647529	431	34.3	221	427	19	219	1.0e-39	157	COG0765	ABC-type amino acid transport system, permease component	222
647647530	256	63.18	16	254	3	240	4.0e-116	411	COG1126	ABC-type polar amino acid transport system, ATPase component	240
647647531	167	30.12	1	162	1	163	9.0e-29	119	COG2062	Phosphohistidine phosphatase SixA	163
647647532	287	51.53	31	286	4	265	3.0e-79	288	COG0548	Acetylglutamate kinase	265
647647533	216	45.88	22	215	2	195	4.0e-61	227	COG0218	GTP-binding protein EngB required for normal cell division	200
647647535	616	36.2	270	600	6	314	1.0e-62	234	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
647647536	496	35.06	228	478	2	249	1.0e-58	220	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
647647537	275	34.14	23	268	1	242	1.0e-48	186	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
647647542	244	27.32	18	200	9	190	1.0e-15	76.5	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
647647543	472	35.9	4	446	3	454	7.0e-103	368	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
647647544	461	22.49	123	456	1	329	2.0e-31	131	COG0642	Signal transduction histidine kinase	336
647647548	372	45	16	372	9	346	1.0e-67	250	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
647647549	223	45.37	1	222	1	226	4.0e-57	214	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647647550	447	27.44	122	447	8	327	1.0e-31	131	COG0642	Signal transduction histidine kinase	336
647647551	321	40.55	1	319	1	326	2.0e-61	229	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647647553	174	42.76	1	144	1	143	5.0e-28	117	COG3427	Carbon monoxide dehydrogenase subunit G	146
647647554	309	33.33	1	306	1	293	2.0e-64	239	COG1131	ABC-type multidrug transport system, ATPase component	293
647647556	265	36.76	12	258	59	309	1.0e-51	196	COG0616	Periplasmic serine protease, ClpP class	317
647647558	317	39.1	3	313	12	315	4.0e-45	175	COG0530	Ca2+/Na+ antiporter	320
647647559	259	32.17	1	246	5	250	1.0e-26	113	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647647560	621	46.94	13	617	3	581	0.0e+00	626	COG0322	Excinuclease UvrABC, nuclease subunit	581
647647561	221	38.89	1	142	10	150	1.0e-18	86.6	COG0558	Phosphatidylglycerophosphate synthase	192
647647562	81	38.27	3	81	4	84	1.0e-12	65	COG1977	Molybdopterin converting factor, small subunit	84
647647563	147	41.5	1	146	4	149	5.0e-39	153	COG0314	Molybdopterin synthase catalytic subunit	149
647647564	632	31.62	466	600	54	189	2.0e-22	101	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
647647565	328	37.67	28	327	1	289	2.0e-44	173	COG0382	4-hydroxybenzoate polyprenyltransferase	289
647647566	240	34.02	5	238	4	246	2.0e-49	189	COG1385	16S rRNA U1498 N3-methylase RsmE	246
647647568	456	53.33	10	456	10	456	0.0e+00	540	COG3572	Gamma-glutamylcysteine synthetase	456
647647570	203	44.22	8	199	2	200	1.0e-39	156	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
647647571	425	40.24	1	424	2	422	3.0e-102	365	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
647647574	335	48.56	20	323	2	310	6.0e-103	367	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
647647575	257	45.54	69	257	4	202	5.0e-41	161	COG1573	Uracil-DNA glycosylase	202
647647576	201	40.89	3	196	2	204	1.0e-22	99	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
647647577	180	45.78	10	173	5	169	8.0e-48	183	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
647647579	1133	24.25	11	1031	1	1005	1.0e-125	445	COG0841	Multidrug efflux pump subunit AcrB	1009
647647580	357	46.89	47	255	4	211	1.0e-55	210	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
647647581	571	32.78	31	444	3	386	5.0e-61	229	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647647582	349	20.39	25	279	8	229	2.0e-16	80.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647647586	240	30.4	1	225	3	225	2.0e-29	123	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
647647587	295	31.33	31	274	17	265	3.0e-49	188	COG1526	Formate dehydrogenase assembly factor FdhD	266
647647588	200	37.13	1	200	2	192	3.0e-37	148	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
647647589	163	49.69	1	159	2	161	2.0e-37	148	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
647647590	682	41.6	287	680	7	404	2.0e-95	344	COG0303	Molybdopterin biosynthesis enzyme	404
647647591	344	54.68	1	339	1	338	2.0e-122	431	COG3839	ABC-type sugar transport system, ATPase component	338
647647592	473	33.12	9	467	4	461	1.0e-88	320	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
647647593	297	34.71	166	286	3	123	3.0e-20	92.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647647594	255	34.98	9	253	2	251	5.0e-34	138	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647647595	278	34.91	9	278	8	281	1.0e-43	170	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
647647596	313	30.89	1	309	6	289	9.0e-36	144	COG1175	ABC-type sugar transport system, permease component	295
647647597	431	22.12	8	427	13	432	5.0e-29	122	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
647647599	160	52.67	10	159	1	150	4.0e-40	157	COG0782	Transcription elongation factor, GreA/GreB family	151
647647600	549	33.33	8	462	1	396	4.0e-74	272	COG0644	Dehydrogenase (flavoprotein)	396
647647602	285	39.71	13	280	5	280	1.0e-63	236	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
647647603	332	34.45	11	332	1	322	3.0e-76	278	COG0142	Geranylgeranyl pyrophosphate synthase	322
647647605	249	31.3	5	242	4	242	7.0e-42	164	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
647647608	240	40	1	237	4	250	1.0e-42	166	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647647609	391	48.51	1	391	1	392	4.0e-90	325	COG0183	Acetyl-CoA acetyltransferase	392
647647610	285	32.9	37	264	10	239	2.0e-47	182	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
647647611	195	56.83	5	185	1	183	1.0e-72	265	COG2818	3-methyladenine DNA glycosylase Tag	188
647647612	384	42.31	5	364	4	348	3.0e-91	329	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
647647613	256	39.43	1	240	1	242	1.0e-44	173	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647647614	206	50	1	205	1	205	7.0e-54	203	COG0522	Ribosomal protein S4 or related protein	205
647647616	314	39.75	3	313	43	353	4.0e-77	281	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
647647617	306	39.51	3	287	1	279	4.0e-70	258	COG0287	Prephenate dehydrogenase	279
647647618	253	28.91	17	253	46	300	2.0e-33	135	COG3921	Uncharacterized conserved protein	300
647647619	334	22.82	4	331	19	338	2.0e-13	70	COG4093	Uncharacterized protein	338
647647620	176	52.91	4	174	13	182	5.0e-48	183	COG3703	Cation transport regulator ChaC	190
647647622	598	24.04	391	598	38	243	5.0e-24	106	COG1360	Flagellar motor protein MotB	244
647647624	773	46.04	4	753	2	782	0.0e+00	849	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
647647625	255	30.86	11	224	22	248	3.0e-19	89.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647647627	512	66.21	1	512	1	501	0.0e+00	792	COG0056	FoF1-type ATP synthase, alpha subunit	504
647647628	292	46.21	5	292	1	286	1.0e-86	313	COG0224	FoF1-type ATP synthase, gamma subunit	287
647647629	479	74.47	9	477	2	468	0.0e+00	797	COG0055	FoF1-type ATP synthase, beta subunit	468
647647630	145	32.11	4	110	3	111	3.0e-19	88	COG0355	FoF1-type ATP synthase, epsilon subunit	135
647647632	339	53.14	8	324	6	314	2.0e-104	372	COG0462	Phosphoribosylpyrophosphate synthetase	314
647647633	198	36.08	4	195	10	201	1.0e-31	130	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
647647634	262	22.99	2	262	9	282	3.0e-14	72.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647647635	345	36.31	1	345	2	337	2.0e-78	285	COG2008	Threonine aldolase	342
647647636	147	61.11	3	146	9	149	8.0e-47	179	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
647647637	310	43.87	1	308	1	304	9.0e-83	300	COG0196	FAD synthase	304
647647638	147	35.81	6	145	11	158	2.0e-19	88.2	COG2030	Acyl dehydratase	159
647647639	294	29.41	12	263	1	242	5.0e-39	154	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
647647641	188	21.02	5	172	2	177	3.0e-11	61.7	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
647647642	306	38.94	3	304	4	304	1.0e-65	243	COG1227	Inorganic pyrophosphatase/exopolyphosphatase	311
647647643	226	43.32	6	218	3	213	3.0e-44	172	COG5482	Uncharacterized protein	229
647647644	71	60.87	2	70	26	94	2.0e-19	87.5	COG0234	Co-chaperonin GroES (HSP10)	96
647647645	549	49.64	1	535	1	524	0.0e+00	515	COG0459	Chaperonin GroEL (HSP60 family)	524
647647647	162	30.95	13	138	4	125	7.0e-14	70.1	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
647647648	269	21.11	10	251	43	301	1.0e-11	64	COG1075	Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold	336
647647649	380	34.75	6	349	3	355	6.0e-49	188	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
647647650	355	51.99	8	355	1	352	2.0e-125	442	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
647647651	144	58.04	1	143	18	158	2.0e-46	178	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
647647652	74	48.33	15	74	9	67	3.0e-07	46.9	COG5481	Uncharacterized protein	67
647647653	118	36.97	1	114	28	145	7.0e-19	85.8	COG0071	Molecular chaperone IbpA, HSP20 family	146
647647656	570	45.21	34	397	33	387	2.0e-112	400	COG2046	ATP sulfurylase (sulfate adenylyltransferase)	397
647647657	334	51.13	5	311	2	302	4.0e-87	315	COG0492	Thioredoxin reductase	305
647647658	166	38.71	1	155	1	154	9.0e-36	142	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647647662	251	42.86	1	251	1	247	4.0e-68	251	COG1496	Copper oxidase (laccase) domain	249
647647663	354	35.41	1	353	1	368	9.0e-75	274	COG1565	SAM-dependent methyltransferase, MidA family	370
647647664	315	38.61	21	315	1	277	4.0e-58	218	COG0682	Prolipoprotein diacylglyceryltransferase	287
647647665	80	37.97	1	79	10	88	2.0e-11	60.8	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
647647667	166	31.33	1	166	1	166	5.0e-30	123	COG5465	Uncharacterized protein	166
647647668	271	43.66	11	271	4	266	6.0e-59	220	COG0345	Pyrroline-5-carboxylate reductase	266
647647669	112	31.58	3	110	10	122	2.0e-15	74.6	COG0073	tRNA-binding EMAP/Myf domain	123
647647670	316	40.68	3	316	4	321	3.0e-77	282	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
647647671	192	40.93	1	192	3	195	1.0e-67	248	COG1435	Thymidine kinase	201
647647672	239	29.95	32	225	1	184	2.0e-33	136	COG0431	NAD(P)H-dependent FMN reductase	184
647647673	374	27.35	1	370	1	320	3.0e-63	235	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
647647674	340	27.59	32	339	51	358	5.0e-38	152	COG4850	Phosphatidate phosphatase APP1	373
647647675	1110	66.1	13	425	1	397	0.0e+00	551	COG0458	Carbamoylphosphate synthase large subunit	400
647647676	254	26.84	1	251	9	279	5.0e-18	85.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647647677	131	36.22	1	125	6	131	6.0e-19	86.4	COG1917	Cupin domain protein related to quercetin dioxygenase	131
647647678	425	67.14	4	423	2	413	0.0e+00	674	COG0112	Glycine/serine hydroxymethyltransferase	413
647647679	266	29.64	18	266	25	276	3.0e-50	192	COG0061	NAD kinase	281
647647680	66	40	1	65	3	67	3.0e-07	46.8	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
647647682	631	37.46	44	600	1	522	0.0e+00	537	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
647647685	757	55.32	6	434	16	432	0.0e+00	541	COG0281	Malic enzyme	432
647647686	131	44.19	3	131	6	134	2.0e-36	144	COG0295	Cytidine deaminase	134
647647687	434	45.85	1	433	2	434	2.0e-118	419	COG0213	Thymidine phosphorylase	435
647647688	397	49.75	1	396	1	386	2.0e-123	436	COG1015	Phosphopentomutase	397
647647689	215	61.84	10	215	4	210	3.0e-81	294	COG0035	Uracil phosphoribosyltransferase	210
647647691	243	19.32	47	235	11	214	3.0e-07	49.1	COG2755	Lysophospholipase L1 or related esterase	216
647647694	381	57.71	25	225	3	202	1.0e-75	277	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
647647695	552	36.7	31	550	10	526	8.0e-106	377	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647647698	733	43.75	327	612	3	289	1.0e-76	281	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
647647700	403	36.34	1	403	1	392	2.0e-72	266	COG0183	Acetyl-CoA acetyltransferase	392
647647701	212	25.62	3	199	1	200	1.0e-22	99.9	COG0625	Glutathione S-transferase	211
647647703	593	31.29	39	456	11	393	1.0e-65	245	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647647704	133	38.05	6	116	1	111	4.0e-13	67.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
647647706	125	30.83	6	123	1	119	2.0e-10	58.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
647647707	142	31.69	1	142	2	140	4.0e-23	100	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
647647708	166	24.2	10	165	4	140	1.0e-12	66.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
647647709	454	28.97	24	453	14	447	1.0e-52	201	COG0534	Na+-driven multidrug efflux pump	455
647647710	115	35.09	1	113	2	115	4.0e-22	96.4	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
647647711	347	44.52	44	341	1	306	3.0e-75	275	COG0167	Dihydroorotate dehydrogenase	310
647647713	87	54.88	2	82	32	113	9.0e-23	98.5	COG3502	Uncharacterized conserved protein, DUF952 family	115
647647715	518	35.61	2	510	1	504	2.0e-85	310	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
647647717	223	39.73	2	218	6	224	3.0e-46	178	COG2135	Putative SOS response-associated peptidase YedK	226
647647719	297	29.69	9	295	1	293	1.0e-33	137	COG0583	DNA-binding transcriptional regulator, LysR family	297
647647720	407	34.86	27	407	1	393	4.0e-79	288	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647647721	728	35.33	400	725	8	323	2.0e-55	210	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
647647722	410	34.27	1	382	4	371	4.0e-69	255	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
647647723	412	24.14	46	387	51	385	2.0e-15	77.6	COG2814	Predicted arabinose efflux permease, MFS family	394
647647724	441	31.22	22	435	12	436	2.0e-73	270	COG0015	Adenylosuccinate lyase	438
647647725	236	20.77	4	236	24	281	2.0e-09	56.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647647726	262	28.07	1	259	2	282	7.0e-27	114	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647647727	323	44.83	3	319	9	324	9.0e-90	323	COG1171	Threonine dehydratase	347
647647728	274	24.1	1	266	1	274	1.0e-13	70.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647647729	272	26.43	45	269	2	225	2.0e-24	106	COG1011	FMN phosphatase YigB, HAD superfamily	229
647647730	142	42.86	3	141	2	140	5.0e-32	129	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
647647731	370	34.18	5	345	1	354	1.0e-69	257	COG0116	23S rRNA G2445 N2-methylase RlmL	381
647647732	263	60.39	4	258	3	256	2.0e-101	362	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
647647733	412	45.63	4	410	2	411	9.0e-114	403	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
647647734	169	30.19	13	169	1	147	1.0e-32	132	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
647647735	139	26.24	1	139	1	138	1.0e-20	92.3	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
647647736	262	23.83	12	258	32	263	3.0e-32	132	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
647647737	212	27.02	4	206	3	250	5.0e-21	94.9	COG1192	Cellulose biosynthesis protein BcsQ	259
647647739	462	48.3	28	462	3	436	0.0e+00	502	COG0621	tRNA A37 methylthiotransferase MiaB	437
647647742	329	48.02	1	326	8	332	9.0e-95	340	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
647647743	171	36.97	4	168	5	153	3.0e-30	124	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
647647745	505	33.01	3	492	10	511	3.0e-71	262	COG0815	Apolipoprotein N-acyltransferase	518
647647746	394	58.04	2	394	1	386	0.0e+00	557	COG0192	S-adenosylmethionine synthetase	388
647647747	242	26.77	10	136	1	125	2.0e-11	63.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
647647748	233	35.78	7	233	1	225	2.0e-50	192	COG0220	tRNA G46 methylase TrmB	227
647647749	450	42.11	16	445	11	428	3.0e-105	375	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
647647750	204	44.65	2	198	3	217	2.0e-54	205	COG0283	Cytidylate kinase	222
647647751	125	25.23	19	124	8	107	2.0e-10	58	COG0607	Rhodanese-related sulfurtransferase	110
647647752	553	53.64	1	548	2	541	0.0e+00	543	COG0539	Ribosomal protein S1	541
647647753	94	51.09	1	92	2	92	3.0e-27	113	COG0776	Bacterial nucleoid DNA-binding protein	94
647647755	214	44.71	7	214	4	207	7.0e-56	210	COG0135	Phosphoribosylanthranilate isomerase	208
647647756	277	61.03	4	275	5	276	7.0e-117	413	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
647647757	510	23.1	143	507	4	370	7.0e-31	128	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
647647758	219	29.27	20	216	42	241	4.0e-38	151	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
647647759	292	37.23	9	282	23	296	5.0e-56	211	COG1230	Co/Zn/Cd efflux system component	296
647647760	114	31.37	1	102	2	100	4.0e-07	46.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
647647761	195	23.23	1	191	10	201	3.0e-32	131	COG1573	Uracil-DNA glycosylase	202
647647763	351	54.36	1	344	1	338	5.0e-126	444	COG3839	ABC-type sugar transport system, ATPase component	338
647647764	289	38.63	12	285	3	276	1.0e-55	210	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
647647765	293	35.05	2	290	1	290	1.0e-52	200	COG1175	ABC-type sugar transport system, permease component	295
647647766	423	23.46	6	418	26	433	2.0e-35	144	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
647647767	277	15.82	80	263	64	258	1.0e-06	47.1	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
647647768	473	37.03	25	470	15	457	1.0e-81	297	COG0277	FAD/FMN-containing dehydrogenase	459
647647769	176	50.29	1	175	5	179	2.0e-46	178	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
647647770	290	40.98	5	243	18	257	1.0e-62	233	COG0005	Purine nucleoside phosphorylase	262
647647771	553	34.92	25	525	15	526	3.0e-95	342	COG0659	Sulfate permease or related transporter, MFS superfamily	554
647647772	210	32.09	18	204	4	176	3.0e-29	121	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
647647773	159	37.11	1	155	6	163	7.0e-26	109	COG3153	Predicted N-acetyltransferase YhbS	171
647647775	362	47.62	3	357	2	352	2.0e-100	359	COG4148	ABC-type molybdate transport system, ATPase component	352
647647776	229	53.81	4	225	2	223	1.0e-56	212	COG4149	ABC-type molybdate transport system, permease component	225
647647777	250	39.22	9	249	4	258	3.0e-45	175	COG0725	ABC-type molybdate transport system, periplasmic component	258
647647778	161	17.14	10	139	1	139	1.0e-05	42.7	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
647647779	154	39.6	1	149	1	138	4.0e-31	127	COG5319	Uncharacterized protein	142
647647780	214	31.6	2	197	8	214	8.0e-24	103	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647647781	412	40.13	1	409	1	447	6.0e-109	387	COG0527	Aspartokinase	447
647647782	753	45.43	13	744	5	745	0.0e+00	677	COG3605	Signal transduction protein containing GAF and PtsI domains	756
647647784	1021	34.09	2	997	1	1009	0.0e+00	804	COG0841	Multidrug efflux pump subunit AcrB	1009
647647785	386	45.05	4	386	2	377	8.0e-96	344	COG1454	Alcohol dehydrogenase, class IV	377
647647786	146	27.74	10	144	1	135	3.0e-19	87.6	COG0824	Acyl-CoA thioesterase FadM	137
647647793	252	42.69	1	250	2	254	7.0e-56	210	COG1484	DNA replication protein DnaC	254
647647794	442	23.66	2	224	52	270	4.0e-28	119	COG4584	Transposase	278
647647798	300	50.33	5	299	6	305	4.0e-74	271	COG3948	Phage-related baseplate assembly protein	306
647647805	393	45.98	1	392	3	391	2.0e-102	366	COG3497	Phage tail sheath protein FI	394
647647806	168	41.42	1	168	1	169	1.0e-42	166	COG3498	Phage tail tube protein FII	169
647647809	137	36.15	4	133	1	130	1.0e-27	115	COG3499	Phage protein U	147
647647811	335	29.11	4	333	3	340	8.0e-37	147	COG3500	Phage protein D	350
647647815	286	32.5	165	281	23	142	3.0e-16	79.4	COG2030	Acyl dehydratase	159
647647816	136	34.75	9	123	10	125	2.0e-18	85	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
647647817	381	28.17	6	374	4	389	3.0e-38	152	COG0183	Acetyl-CoA acetyltransferase	392
647647818	261	33.47	1	245	1	249	5.0e-37	148	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647647819	819	33.66	416	818	5	396	2.0e-67	250	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
647647820	265	34.6	1	262	3	257	5.0e-43	167	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647647821	534	38.85	1	527	10	532	9.0e-116	411	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647647822	384	44.16	7	381	5	388	8.0e-86	310	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647647823	300	31.37	1	245	2	246	2.0e-35	143	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647647824	159	30.08	26	148	1	123	7.0e-13	66.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
647647825	384	36.78	4	383	2	396	1.0e-83	304	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
647647826	325	29.94	1	320	4	334	2.0e-61	229	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
647647827	353	22.52	1	324	1	321	2.0e-27	116	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647647829	446	35.09	65	442	2	375	1.0e-61	230	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647647830	508	32	6	502	2	522	2.0e-93	336	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647647834	763	34.04	420	723	80	408	1.0e-35	145	COG0840	Methyl-accepting chemotaxis protein	408
647647837	402	48.81	1	375	3	377	2.0e-121	429	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
647647838	278	35.08	12	254	4	248	1.0e-54	206	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
647647841	339	26.39	1	324	3	333	1.0e-41	163	COG0673	Predicted dehydrogenase	342
647647842	378	47.04	2	362	1	370	6.0e-106	377	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
647647843	333	33.64	11	325	2	314	4.0e-51	195	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647647844	392	39.9	1	378	5	372	1.0e-97	349	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
647647846	247	29.67	25	233	3	206	1.0e-25	110	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
647647847	482	22.71	1	449	7	463	4.0e-14	73.2	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
647647849	347	36.14	6	316	1	314	5.0e-54	205	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647647850	483	39.11	283	483	40	226	8.0e-48	185	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
647647851	435	21.67	29	423	19	423	4.0e-12	66.3	COG3307	O-antigen ligase	424
647647853	320	21.81	6	244	1	242	2.0e-19	90.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
647647854	364	24.46	1	349	2	373	4.0e-32	132	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647647855	700	22.34	15	467	15	458	1.0e-26	115	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
647647856	372	69.94	1	356	2	345	0.0e+00	563	COG1089	GDP-D-mannose dehydratase	345
647647857	323	33.53	5	317	4	311	1.0e-42	167	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647647859	888	20.57	164	690	5	508	2.0e-06	48.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
647647861	224	32.98	14	201	1	187	1.0e-37	150	COG2518	Protein-L-isoaspartate O-methyltransferase	209
647647862	479	30.17	33	446	44	457	1.0e-38	154	COG1538	Outer membrane protein TolC	457
647647865	187	39.69	1	131	1	131	5.0e-36	144	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
647647866	323	43.77	4	322	1	315	3.0e-96	345	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
647647867	324	53.48	4	317	1	313	4.0e-123	434	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
647647868	292	46.26	14	292	9	289	3.0e-67	248	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647647869	325	44.72	4	325	3	317	7.0e-84	304	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647647873	311	27.08	3	288	1	284	4.0e-30	125	COG0583	DNA-binding transcriptional regulator, LysR family	297
647647874	541	31.01	1	538	4	530	2.0e-83	303	COG1574	Predicted amidohydrolase YtcJ	535
647647875	291	31.72	5	277	1	307	5.0e-40	158	COG0523	GTPase, G3E family	323
647647876	247	30.8	3	240	21	283	5.0e-39	154	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
647647877	224	24.24	1	219	1	229	2.0e-10	59.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
647647878	620	36.76	9	581	1	567	1.0e-117	417	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647647879	381	35.26	2	378	17	381	3.0e-72	265	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
647647881	379	37.19	17	374	1	353	3.0e-74	272	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
647647883	263	33.96	1	261	4	257	1.0e-37	149	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647647884	1025	41.03	3	1023	1	877	0.0e+00	978	COG0525	Valyl-tRNA synthetase	877
647647885	621	33.67	8	597	8	577	1.0e-103	371	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
647647887	161	29.75	37	157	18	137	1.0e-18	85.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
647647888	288	42.09	6	278	17	289	4.0e-62	231	COG0685	5,10-methylenetetrahydrofolate reductase	291
647647889	301	29.67	3	300	1	296	1.0e-33	137	COG0583	DNA-binding transcriptional regulator, LysR family	297
647647890	346	52.45	1	346	5	339	7.0e-116	410	COG2130	NADPH-dependent curcumin reductase CurA	340
647647891	261	46.18	7	253	5	253	2.0e-67	249	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
647647892	224	28.99	20	224	11	182	1.0e-19	89.8	COG0693	Putative intracellular protease/amidase	188
647647893	125	31.07	6	107	2	102	2.0e-15	74.7	COG3791	Uncharacterized conserved protein	133
647647894	247	34.5	1	222	2	221	6.0e-27	114	COG0705	Membrane associated serine protease, rhomboid family	228
647647896	161	49.32	9	154	4	148	8.0e-32	129	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647647905	246	23.58	18	220	51	260	2.0e-16	79.6	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
647647906	294	26.35	3	290	2	297	5.0e-24	105	COG0583	DNA-binding transcriptional regulator, LysR family	297
647647907	326	33.33	7	325	3	324	5.0e-48	185	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647647908	261	41.67	2	251	1	251	1.0e-35	143	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647647911	295	32.21	4	295	3	293	2.0e-34	139	COG0583	DNA-binding transcriptional regulator, LysR family	297
647647912	207	38.83	1	197	3	205	2.0e-33	135	COG0655	Multimeric flavodoxin WrbA	207
647647913	212	23.62	1	187	3	192	2.0e-19	88.8	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
647647914	312	25.47	29	287	36	292	1.0e-05	44.1	COG5006	Threonine/homoserine efflux transporter RhtA	292
647647915	250	36.68	20	243	9	237	8.0e-30	123	COG2186	DNA-binding transcriptional regulator, FadR family	241
647647916	328	26.52	1	322	1	311	6.0e-34	138	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647647917	323	42.38	1	322	2	329	4.0e-86	311	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647647918	168	34.13	1	167	2	168	7.0e-16	76.9	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647647919	426	47.48	46	422	1	377	8.0e-90	324	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647647920	294	40.42	1	283	1	286	4.0e-60	225	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
647647921	411	43.37	1	409	1	413	3.0e-93	335	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
647647922	215	34.29	1	205	3	207	4.0e-39	154	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
647647923	257	45.7	2	254	3	258	1.0e-74	272	COG3622	Hydroxypyruvate isomerase	260
647647924	1222	47.5	445	1219	7	767	0.0e+00	794	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
647647926	812	31.76	27	783	53	865	3.0e-129	456	COG3002	Uncharacterized conserved protein YbcC, UPF0753/DUF2309 family	880
647647928	296	28.72	4	288	1	285	4.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
647647929	255	26.98	12	221	13	226	6.0e-29	121	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647647930	135	31.3	27	133	2	115	3.0e-13	67.9	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
647647931	570	40.21	1	567	4	558	0.0e+00	557	COG0143	Methionyl-tRNA synthetase	558
647647932	436	23.53	26	401	9	388	6.0e-06	46	COG2807	Cyanate permease	395
647647933	371	37.32	26	371	1	315	4.0e-73	268	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
647647934	298	49.16	1	295	1	298	4.0e-96	344	COG3246	Uncharacterized conserved protein, DUF849 family	298
647647936	491	30.23	1	306	2	304	8.0e-57	215	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
647647937	197	39.71	1	189	5	205	5.0e-26	111	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647647941	133	37.5	12	131	6	125	3.0e-24	104	COG5349	Uncharacterized conserved protein, DUF983 family	126
647647943	436	37.08	251	424	1	177	9.0e-28	118	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
647647945	172	26.35	21	168	5	148	5.0e-06	44.3	COG5612	Uncharacterized membrane protein	148
647647952	476	36.44	6	476	1	410	1.0e-95	344	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
647647953	423	28.64	34	407	1	384	3.0e-49	189	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647647954	67	45.59	2	67	25	92	1.0e-13	68.1	COG4311	Sarcosine oxidase delta subunit	97
647647955	977	32.83	585	977	2	379	5.0e-80	293	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
647647956	169	31.97	28	166	43	189	5.0e-15	74.2	COG4583	Sarcosine oxidase gamma subunit	189
647647958	650	37.45	2	488	8	485	2.0e-100	360	COG0358	DNA primase (bacterial type)	568
647647959	671	51.5	340	670	10	342	4.0e-96	346	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
647647961	136	36.96	1	135	4	135	1.0e-30	125	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
647647962	155	52.26	1	155	1	155	7.0e-52	196	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
647647963	356	58.82	1	136	10	145	5.0e-51	195	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
647647964	678	39.62	32	648	12	641	4.0e-124	439	COG3563	Capsule polysaccharide export protein KpsC/LpsZ	671
647647965	364	26.87	39	263	25	239	2.0e-22	100	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
647647966	430	32.22	9	390	14	393	1.0e-60	227	COG3562	Capsule polysaccharide modification protein KpsS	403
647647967	195	45.92	1	194	1	194	1.0e-61	229	COG0307	Riboflavin synthase alpha chain	204
647647969	165	41.73	2	136	14	152	1.0e-29	122	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
647647970	159	33.1	16	158	10	149	1.0e-19	89.2	COG0781	Transcription termination factor NusB	151
647647973	152	50.41	17	139	26	148	2.0e-31	128	COG5321	Uncharacterized protein	164
647647977	344	42.28	8	329	5	288	2.0e-73	269	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
647647978	298	38.28	7	292	60	338	2.0e-65	242	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
647647979	323	30.45	1	323	1	335	3.0e-47	182	COG0673	Predicted dehydrogenase	342
647647980	89	29.41	1	77	36	120	1.0e-07	48.5	COG1734	RNA polymerase-binding transcription factor DksA	120
647647981	192	23.64	6	115	4	104	3.0e-08	51.8	COG1544	Ribosome-associated translation inhibitor RaiA	110
647647982	610	34.45	22	610	5	597	0.0e+00	502	COG1164	Oligoendopeptidase F	598
647647983	532	30.23	71	526	12	441	6.0e-60	225	COG1793	ATP-dependent DNA ligase	444
647647984	337	21.08	7	329	19	424	8.0e-31	127	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
647647985	315	27.39	12	314	2	296	3.0e-36	145	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
647647989	112	43.94	4	65	5	68	2.0e-07	48.2	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
647647990	425	52.13	1	419	1	422	4.0e-119	421	COG2379	Glycerate-2-kinase	422
647647992	328	33.23	3	327	1	308	1.0e-47	183	COG2017	Galactose mutarotase or related enzyme	308
647647993	157	31.25	28	139	12	123	3.0e-11	61.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
647647994	421	21.94	28	386	31	377	7.0e-18	85.3	COG2814	Predicted arabinose efflux permease, MFS family	394
647647995	156	34.78	12	149	19	153	7.0e-30	123	COG2030	Acyl dehydratase	159
647647996	334	49.55	2	330	8	339	2.0e-93	336	COG2130	NADPH-dependent curcumin reductase CurA	340
647647997	332	43.58	1	331	1	326	3.0e-75	275	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647647998	391	32.77	51	391	42	391	3.0e-50	193	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647647999	371	25.91	3	368	2	385	4.0e-41	162	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647648000	275	39.53	9	261	1	250	5.0e-41	161	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647648001	309	39.64	4	222	1	213	2.0e-32	133	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647648002	398	35.18	1	398	1	392	1.0e-72	266	COG0183	Acetyl-CoA acetyltransferase	392
647648003	215	22.84	1	189	2	189	1.0e-13	70.2	COG0406	Broad specificity phosphatase PhoE	208
647648004	343	35.44	1	329	1	318	6.0e-60	224	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
647648005	358	24.55	2	330	41	363	1.0e-36	147	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
647648006	318	29.72	1	317	3	294	1.0e-41	163	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
647648007	431	27.21	28	328	9	308	1.0e-38	154	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
647648008	253	44.4	2	247	1	250	3.0e-74	272	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
647648009	234	47.03	1	234	2	237	4.0e-76	277	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
647648010	400	29.85	2	400	32	383	1.0e-40	160	COG1680	CubicO group peptidase, beta-lactamase class C family	390
647648011	652	33.76	79	622	1	526	4.0e-102	366	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
647648012	290	47.6	1	289	1	289	1.0e-88	319	COG1946	Acyl-CoA thioesterase	289
647648013	351	23.1	28	348	1	278	1.0e-24	107	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
647648015	263	34.25	3	209	4	221	7.0e-32	131	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647648016	255	39.29	4	250	1	249	5.0e-49	188	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647648017	423	29.9	16	400	12	390	4.0e-61	228	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647648018	259	47.31	1	256	2	257	2.0e-55	209	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647648019	430	41.39	33	320	1	302	6.0e-81	295	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
647648020	560	34.97	36	556	10	524	6.0e-95	342	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647648023	160	32.74	46	157	12	124	3.0e-09	54.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
647648024	604	22.57	36	540	11	493	2.0e-48	187	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647648025	369	28.49	33	365	7	332	2.0e-40	160	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647648026	260	33.59	7	259	3	257	7.0e-39	154	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647648027	306	34.9	14	306	7	291	3.0e-58	219	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
647648028	401	23.96	11	383	2	405	2.0e-10	60.4	COG1228	Imidazolonepropionase or related amidohydrolase	406
647648029	268	28.73	14	266	2	266	3.0e-41	162	COG1018	Ferredoxin-NADP reductase	266
647648030	278	35.56	1	278	4	284	4.0e-46	178	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
647648031	915	34.88	169	911	6	731	0.0e+00	474	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
647648033	285	35.35	9	216	11	217	5.0e-28	118	COG2122	Uncharacterized protein, UPF0280 family, ApbE superfamily	256
647648036	146	30.39	42	143	19	120	3.0e-10	58	COG1846	DNA-binding transcriptional regulator, MarR family	126
647648037	355	25.78	3	338	23	359	6.0e-34	138	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
647648038	405	31.25	21	382	1	363	6.0e-41	161	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
647648039	822	45.56	567	810	3	250	1.0e-73	272	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
647648040	233	52.77	1	233	3	237	2.0e-80	291	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
647648041	336	39.88	1	325	1	311	1.0e-71	263	COG2826	Transposase and inactivated derivatives, IS30 family	318
647648042	491	40.53	11	491	16	497	0.0e+00	464	COG2317	Zn-dependent carboxypeptidase, M32 family	497
647648045	321	50.47	5	317	2	315	1.0e-116	413	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
647648046	312	40.69	23	312	7	288	5.0e-65	241	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647648047	342	44.89	19	340	1	317	7.0e-87	314	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647648049	480	31.65	1	468	17	498	2.0e-68	253	COG0747	ABC-type transport system, periplasmic component	556
647648050	311	34.34	4	102	15	112	4.0e-15	76	COG1725	DNA-binding transcriptional regulator YhcF, GntR family	125
647648051	233	31.84	1	229	1	242	2.0e-30	126	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
647648052	339	29.01	6	327	3	307	1.0e-40	160	COG1893	Ketopantoate reductase	307
647648053	251	38.22	3	251	1	251	4.0e-35	141	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647648054	298	27.52	11	226	20	235	3.0e-19	89.3	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
647648055	311	51.45	6	310	3	307	7.0e-76	277	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
647648056	436	25.71	28	398	1	375	9.0e-42	164	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647648057	204	24.35	16	129	2	116	6.0e-09	54.3	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
647648058	556	51.49	15	550	3	537	0.0e+00	635	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
647648059	550	27.34	1	548	1	555	1.0e-82	301	COG0747	ABC-type transport system, periplasmic component	556
647648060	316	46.37	1	316	1	316	7.0e-89	320	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647648061	292	49.28	13	289	9	286	6.0e-70	257	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647648062	326	33.55	27	326	18	324	4.0e-61	228	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
647648064	369	32.86	86	358	38	308	5.0e-36	145	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
647648066	164	28.83	1	163	1	161	1.0e-13	69.6	COG3685	Ferritin-like metal-binding protein YciE	167
647648067	225	27	13	211	4	195	3.0e-11	62.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647648068	392	42.21	29	380	8	351	8.0e-68	251	COG1566	Multidrug resistance efflux pump	352
647648070	530	20.51	32	387	39	383	4.0e-15	76.8	COG2814	Predicted arabinose efflux permease, MFS family	394
647648075	408	46.19	1	407	1	386	1.0e-124	440	COG0754	Glutathionylspermidine synthase	387
647648076	193	27.57	11	193	26	198	5.0e-15	74.3	COG5463	Uncharacterized conserved protein YgiB, involved in bioifilm formation, UPF0441/DUF1190 family	198
647648080	698	32.17	1	681	3	707	0.0e+00	509	COG0643	Chemotaxis protein histidine kinase CheA	716
647648082	814	37.32	441	766	58	408	2.0e-47	184	COG0840	Methyl-accepting chemotaxis protein	408
647648086	626	22.66	31	409	3	353	2.0e-39	157	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647648087	134	31.93	7	125	1	117	2.0e-12	64.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
647648088	446	22	25	415	4	382	3.0e-29	123	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647648091	381	40.9	5	379	2	375	9.0e-112	397	COG1454	Alcohol dehydrogenase, class IV	377
647648092	458	36.44	2	458	13	470	6.0e-98	351	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647648093	442	37.09	1	441	9	443	9.0e-108	384	COG0174	Glutamine synthetase	443
647648094	345	24.93	4	326	3	337	2.0e-25	109	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
647648095	441	32.59	1	440	2	447	2.0e-63	237	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
647648096	173	24.14	1	172	1	173	1.0e-17	83	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
647648097	229	45.37	2	224	28	254	7.0e-63	233	COG3931	Predicted N-formylglutamate amidohydrolase	263
647648098	288	28.67	3	284	1	281	8.0e-43	167	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
647648101	262	24.11	10	256	17	252	2.0e-22	99.7	COG0121	Predicted glutamine amidotransferase	252
647648102	163	34.72	16	159	7	145	1.0e-20	92.8	COG0071	Molecular chaperone IbpA, HSP20 family	146
647648103	175	28.25	1	175	4	151	1.0e-11	62.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
647648106	373	31	54	370	21	337	2.0e-39	156	COG2187	Aminoglycoside phosphotransferase family enzyme	337
647648107	313	33.12	1	312	5	304	9.0e-57	214	COG0462	Phosphoribosylpyrophosphate synthetase	314
647648110	531	37.01	5	466	2	427	7.0e-85	308	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
647648112	600	41.02	150	599	9	445	5.0e-111	395	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
647648113	175	32.2	1	175	4	151	4.0e-12	64.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
647648114	885	33.33	442	869	2	404	3.0e-84	306	COG2312	Erythromycin esterase homolog	405
647648115	147	35.66	7	145	5	146	3.0e-21	94.3	COG0071	Molecular chaperone IbpA, HSP20 family	146
647648116	133	27.27	1	131	13	144	2.0e-20	91.6	COG0071	Molecular chaperone IbpA, HSP20 family	146
647648117	169	39.82	55	167	34	146	1.0e-26	112	COG0071	Molecular chaperone IbpA, HSP20 family	146
647648118	482	44.54	26	380	1	338	1.0e-69	257	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
647648119	184	32.57	4	178	23	193	1.0e-23	102	COG0576	Molecular chaperone GrpE (heat shock protein)	193
647648120	542	34.94	49	374	16	337	5.0e-60	225	COG2187	Aminoglycoside phosphotransferase family enzyme	337
647648124	874	38.91	4	872	37	915	0.0e+00	720	COG0474	Magnesium-transporting ATPase (P-type)	917
647648125	157	32.81	30	156	9	135	7.0e-15	73.5	COG4520	Surface antigen	136
647648126	216	25.49	18	215	1	194	3.0e-23	101	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
647648127	638	27.43	1	172	25	199	1.0e-19	91.9	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
647648129	215	32.26	1	215	7	223	1.0e-29	123	COG1802	DNA-binding transcriptional regulator, GntR family	230
647648130	345	27.22	8	342	15	352	4.0e-32	132	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
647648131	228	18.64	5	227	27	262	3.0e-10	59.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
647648132	322	34.88	1	320	2	318	1.0e-57	216	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
647648133	331	42.73	3	325	35	375	2.0e-81	296	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
647648134	675	31.73	5	500	1	486	2.0e-76	280	COG3333	TctA family transporter	504
647648135	359	22.49	1	334	4	303	1.0e-10	61.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
647648136	224	40	1	222	1	229	3.0e-49	188	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647648137	458	23.81	126	457	3	334	3.0e-30	126	COG0642	Signal transduction histidine kinase	336
647648138	370	36.54	16	363	1	349	5.0e-65	241	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
647648139	271	21.23	59	270	35	241	4.0e-12	65.6	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
647648140	157	41.73	1	139	1	137	3.0e-33	134	COG0848	Biopolymer transport protein ExbD	137
647648141	283	39.81	60	267	1	216	1.0e-36	147	COG0811	Biopolymer transport protein ExbB/TolQ	216
647648142	240	55.22	12	240	1	229	7.0e-79	286	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
647648143	814	32.02	70	814	12	750	6.0e-122	432	COG4774	Outer membrane receptor for monomeric catechols	750
647648146	139	27.54	6	139	7	142	1.0e-05	42	COG5642	Uncharacterized conserved protein, DUF2384 family	149
647648147	132	32.5	1	120	2	118	3.0e-20	90.8	COG1733	DNA-binding transcriptional regulator, HxlR family	120
647648148	355	21.62	3	283	1	280	4.0e-15	75.8	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647648149	467	25.28	30	467	13	446	1.0e-34	141	COG0534	Na+-driven multidrug efflux pump	455
647648150	174	27.54	33	170	5	140	2.0e-18	85.5	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
647648151	147	38.66	1	118	1	119	8.0e-27	113	COG1733	DNA-binding transcriptional regulator, HxlR family	120
647648153	415	49.12	108	389	1	283	3.0e-95	342	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
647648155	237	34.15	3	237	7	252	5.0e-46	177	COG0631	Serine/threonine protein phosphatase PrpC	262
647648156	222	28.49	4	174	7	175	1.0e-17	83.6	COG3913	Uncharacterized protein	227
647648157	1194	37.88	14	1194	14	1187	0.0e+00	889	COG3523	Type VI protein secretion system component VasK	1188
647648158	416	35.92	4	248	16	260	2.0e-53	203	COG3455	Type VI protein secretion system component VasF	262
647648159	446	45.86	1	445	1	446	3.0e-129	455	COG3522	Predicted component of the type VI protein secretion system	446
647648160	481	24.23	26	477	27	424	2.0e-47	184	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
647648163	705	38.25	30	564	34	549	0.0e+00	478	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
647648164	1383	51.81	1	163	1	166	2.0e-48	188	COG3516	Predicted component of the type VI protein secretion system	169
647648167	911	37.32	12	911	1	784	0.0e+00	724	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
647648168	328	40.62	2	318	16	333	3.0e-71	262	COG3520	Predicted component of the type VI protein secretion system	335
647648169	625	41.13	1	620	1	616	0.0e+00	567	COG3519	Type VI protein secretion system component VasA	621
647648170	165	38.36	7	163	4	155	4.0e-18	84.6	COG3518	Predicted component of the type VI protein secretion system	157
647648171	275	41.13	5	268	8	271	3.0e-63	235	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion	273
647648172	172	27.39	1	154	1	153	4.0e-16	78	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
647648173	497	62.05	1	497	1	495	0.0e+00	756	COG3517	Predicted component of the type VI protein secretion system	495
647648174	171	54.17	2	168	1	168	3.0e-55	207	COG3516	Predicted component of the type VI protein secretion system	169
647648175	343	28.18	13	330	14	334	2.0e-20	93.2	COG3515	Predicted component of the type VI protein secretion system	346
647648177	544	21.14	176	542	114	425	5.0e-17	83.1	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
647648181	436	24.59	105	408	1	248	3.0e-28	120	COG1192	Cellulose biosynthesis protein BcsQ	259
647648183	478	33.19	72	300	30	258	2.0e-40	160	COG3455	Type VI protein secretion system component VasF	262
647648184	1087	28.48	9	1086	15	1187	0.0e+00	508	COG3523	Type VI protein secretion system component VasK	1188
647648185	271	37.25	8	252	1	253	4.0e-50	191	COG0631	Serine/threonine protein phosphatase PrpC	262
647648186	698	26.86	125	382	2	277	2.0e-35	144	COG0515	Serine/threonine protein kinase	384
647648189	156	17.91	19	151	18	130	3.0e-06	44.8	COG0848	Biopolymer transport protein ExbD	137
647648190	208	22.45	1	196	13	204	5.0e-16	77.7	COG0811	Biopolymer transport protein ExbB/TolQ	216
647648195	387	34.25	1	357	21	370	4.0e-23	102	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
647648196	1043	52.87	1	1026	2	1009	0.0e+00	1000	COG0841	Multidrug efflux pump subunit AcrB	1009
647648197	349	43.06	1	347	3	351	2.0e-104	372	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
647648198	261	46.27	8	261	11	265	3.0e-58	218	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
647648199	287	39.34	15	285	11	281	2.0e-52	199	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
647648202	309	32.99	3	290	36	312	5.0e-45	175	COG1397	ADP-ribosylglycohydrolase	314
647648203	245	26.05	13	245	3	236	5.0e-27	115	COG2188	DNA-binding transcriptional regulator, GntR family	236
647648205	823	49.33	146	819	68	708	0.0e+00	733	COG2217	Cation transport ATPase	713
647648208	462	31.28	8	462	1	449	2.0e-61	230	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
647648209	181	28.57	27	173	17	138	2.0e-07	48.8	COG2010	Cytochrome c, mono- and diheme variants	150
647648211	219	44.68	1	94	13	106	8.0e-22	97.4	COG1733	DNA-binding transcriptional regulator, HxlR family	120
647648212	468	19.59	39	463	16	451	2.0e-35	144	COG0277	FAD/FMN-containing dehydrogenase	459
647648214	557	37.68	3	548	2	547	0.0e+00	461	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
647648215	692	37.43	5	690	1	674	9.0e-130	457	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
647648216	539	32.43	3	535	1	540	2.0e-94	339	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
647648217	385	40.97	1	384	15	393	5.0e-95	341	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
647648219	401	23.02	1	375	1	368	9.0e-41	161	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647648220	307	24.24	9	298	1	290	6.0e-30	124	COG0583	DNA-binding transcriptional regulator, LysR family	297
647648221	153	41.22	1	146	2	149	1.0e-46	178	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
647648222	245	29.11	7	241	1	212	3.0e-48	185	COG0602	Organic radical activating enzyme	212
647648223	117	38.58	1	117	2	126	2.0e-27	114	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
647648224	215	43.63	1	202	21	222	5.0e-62	230	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
647648225	236	39.29	5	226	20	243	4.0e-38	151	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
647648226	241	38.31	4	239	1	243	1.0e-49	190	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
647648227	228	41.63	21	227	15	217	4.0e-49	188	COG0819	Thiaminase	218
647648228	312	33.76	5	305	14	319	5.0e-37	148	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
647648229	269	56.82	1	264	2	262	1.0e-88	319	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
647648230	213	47.29	3	204	1	202	2.0e-44	172	COG0352	Thiamine monophosphate synthase	211
647648231	257	47.24	7	256	7	260	2.0e-66	245	COG2145	Hydroxyethylthiazole kinase, sugar kinase family	265
647648233	538	35.94	155	513	24	407	4.0e-37	149	COG0840	Methyl-accepting chemotaxis protein	408
647648235	331	45.95	5	313	3	261	5.0e-89	321	COG4608	ABC-type oligopeptide transport system, ATPase component	309
647648236	333	50.46	4	327	1	316	2.0e-109	389	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
647648237	380	34.65	147	374	63	284	2.0e-56	213	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647648238	334	31.19	5	331	2	316	6.0e-51	194	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647648240	489	34.22	4	489	2	479	1.0e-82	300	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
647648241	513	23.15	6	490	6	465	2.0e-48	186	COG3119	Arylsulfatase A or related enzyme	475
647648242	280	31.62	19	271	1	252	3.0e-51	195	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
647648243	253	37.05	7	249	8	257	2.0e-52	199	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
647648244	560	34.9	7	538	7	530	8.0e-93	334	COG1283	Na+/phosphate symporter	533
647648248	263	33.21	6	253	5	267	8.0e-28	117	COG3769	Predicted mannosyl-3-phosphoglycerate phosphatase, HAD superfamily	274
647648251	319	38.56	14	318	1	298	2.0e-75	276	COG2421	Acetamidase/formamidase	305
647648253	253	35.98	1	249	1	251	1.0e-31	129	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647648254	386	37.72	1	383	1	388	1.0e-75	277	COG0183	Acetyl-CoA acetyltransferase	392
647648255	325	30.54	1	320	4	332	1.0e-57	217	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
647648257	250	48.37	1	246	1	244	2.0e-81	295	COG3484	Predicted proteasome-type protease	255
647648258	265	28.47	1	252	11	291	9.0e-34	137	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
647648259	313	36.19	1	312	1	309	3.0e-72	265	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
647648260	475	58.12	8	475	12	478	0.0e+00	666	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
647648263	1144	19.67	2	1129	1	971	3.0e-47	184	COG4717	Uncharacterized protein YhaN	984
647648264	409	25.74	3	383	1	383	1.0e-32	134	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
647648265	722	26.34	7	358	1	370	8.0e-48	185	COG1252	NADH dehydrogenase, FAD-containing subunit	405
647648266	344	31.33	8	255	13	251	2.0e-32	133	COG2603	tRNA 2-selenouridine synthase SelU, contains rhodanese domain	334
647648268	345	62.54	1	344	1	338	0.0e+00	533	COG1088	dTDP-D-glucose 4,6-dehydratase	340
647648269	288	45.07	1	283	1	280	2.0e-77	282	COG1091	dTDP-4-dehydrorhamnose reductase	281
647648270	293	53.55	7	288	1	279	1.0e-103	369	COG1209	dTDP-glucose pyrophosphorylase	286
647648271	279	34.11	31	276	30	281	2.0e-31	129	COG5473	Uncharacterized membrane protein	290
647648276	350	22.89	60	260	1	182	5.0e-06	45.7	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
647648277	455	22.89	14	455	4	407	1.0e-25	111	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
647648278	286	42.05	1	282	8	287	2.0e-66	246	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
647648279	200	28.11	1	176	1	179	1.0e-20	93.4	COG1335	Nicotinamidase-related amidase	205
647648280	688	39.3	8	686	5	674	0.0e+00	526	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
647648281	564	40.97	5	556	2	549	5.0e-130	458	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
647648283	271	34.78	18	247	8	236	6.0e-45	174	COG2188	DNA-binding transcriptional regulator, GntR family	236
647648284	465	48.29	3	461	1	423	0.0e+00	534	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
647648285	196	45.69	1	194	1	191	1.0e-51	196	COG0066	3-isopropylmalate dehydratase small subunit	191
647648286	332	24.44	3	306	5	309	6.0e-27	115	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647648287	168	22.82	1	149	2	147	4.0e-11	61.1	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647648288	435	31.85	54	435	2	377	4.0e-55	209	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647648289	294	20.16	25	279	5	255	1.0e-20	94.3	COG3176	Putative hemolysin	292
647648291	227	47.62	1	210	1	201	5.0e-56	211	COG3316	Transposase (or an inactivated derivative)	215
647648294	427	36.02	24	409	12	378	5.0e-69	255	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
647648296	376	27.25	33	376	9	333	3.0e-32	132	COG0642	Signal transduction histidine kinase	336
647648298	558	33.53	241	555	36	336	4.0e-41	163	COG0642	Signal transduction histidine kinase	336
647648299	258	29.2	4	241	10	256	2.0e-28	120	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
647648300	243	30.38	9	242	3	236	6.0e-38	150	COG2188	DNA-binding transcriptional regulator, GntR family	236
647648301	316	31.43	3	316	5	317	1.0e-49	190	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
647648303	496	44.33	1	494	4	495	1.0e-121	430	COG3333	TctA family transporter	504
647648305	723	25.42	40	717	28	720	2.0e-80	294	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
647648308	155	28.57	1	153	2	149	1.0e-23	102	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
647648311	531	33.6	24	522	8	484	1.0e-71	263	COG3333	TctA family transporter	504
647648313	285	27.84	1	269	32	302	4.0e-23	102	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
647648315	166	18.25	27	152	1	126	1.0e-09	56.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
647648316	475	26.88	1	453	1	475	3.0e-47	183	COG3119	Arylsulfatase A or related enzyme	475
647648322	266	25.13	69	259	36	221	2.0e-12	66.5	COG2801	Transposase InsO and inactivated derivatives	232
647648336	336	39.88	1	325	1	311	1.0e-71	263	COG2826	Transposase and inactivated derivatives, IS30 family	318
647648337	107	31.73	4	105	6	109	7.0e-12	62.4	COG1734	RNA polymerase-binding transcription factor DksA	120
647648338	148	31.76	4	144	20	167	1.0e-06	45.8	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
647648339	148	31.03	9	146	16	160	6.0e-06	43.5	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
647648341	217	28.97	2	206	1	212	7.0e-23	100	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
647648343	235	48.23	5	224	1	226	4.0e-75	274	COG1136	ABC-type lipoprotein export system, ATPase component	226
647648344	787	18.51	433	784	26	406	5.0e-11	63.8	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
647648345	403	26.42	8	389	16	357	1.0e-13	70.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
647648347	345	22.12	7	345	7	320	2.0e-20	93.7	COG0530	Ca2+/Na+ antiporter	320
647648348	380	33.47	7	242	6	230	2.0e-19	90.1	COG1994	Zn-dependent protease (includes SpoIVFB)	230
647648350	224	33.51	29	209	27	211	1.0e-29	123	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
647648351	145	30.71	18	144	9	134	7.0e-16	76.5	COG5502	Uncharacterized conserved protein, DUF2267 family	135
647648355	407	44.82	1	406	1	409	3.0e-127	448	COG2235	Arginine deiminase	409
647648356	301	48.88	1	296	1	312	2.0e-99	355	COG0549	Carbamate kinase	312
647648359	143	41.86	1	128	1	129	2.0e-28	118	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
647648360	298	23.08	4	257	2	250	3.0e-22	99.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647648364	836	34	147	781	16	626	7.0e-118	418	COG1067	Predicted ATP-dependent protease	647
647648366	418	30.79	24	386	16	391	1.0e-18	87.9	COG0531	Amino acid transporter	466
647648367	1488	38.52	233	498	1	268	2.0e-62	235	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
647648368	186	29.83	6	186	4	183	1.0e-10	59.8	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
647648370	375	26.75	6	229	7	233	1.0e-29	124	COG3300	MHYT domain, NO-binding membrane sensor	236
647648371	284	33.22	4	284	2	283	8.0e-51	193	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
647648372	159	55.92	1	151	3	154	5.0e-55	206	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
647648373	804	35.77	17	794	6	726	0.0e+00	517	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
647648374	292	26.69	1	285	11	284	4.0e-32	132	COG0714	MoxR-like ATPase	329
647648375	395	33.68	8	395	5	392	3.0e-54	206	COG3552	Uncharacterized conserved protein, contains von Willebrand factor type A (vWA) domain	395
647648376	286	27.08	9	264	1	259	8.0e-21	94.7	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
647648377	150	44.59	1	147	1	146	7.0e-32	129	COG3427	Carbon monoxide dehydrogenase subunit G	146
647648378	305	37.05	8	223	4	225	4.0e-43	168	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
647648379	596	42.06	8	578	12	579	0.0e+00	533	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
647648382	358	22.56	18	346	17	363	5.0e-10	59	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
647648383	465	20.39	1	446	8	462	6.0e-11	62.4	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
647648389	339	34.29	4	339	16	361	7.0e-66	244	COG0687	Spermidine/putrescine-binding periplasmic protein	363
647648390	267	40.75	4	267	3	263	2.0e-54	206	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
647648391	304	43.97	14	295	7	278	2.0e-61	229	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
647648392	359	52.38	4	357	3	352	2.0e-115	409	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
647648394	441	38.36	2	439	1	447	2.0e-118	419	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
647648395	370	30.21	27	355	1	321	8.0e-46	178	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
647648396	429	26.39	9	423	2	408	1.0e-44	174	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647648397	520	26.17	8	518	2	528	2.0e-72	267	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
647648398	342	35.21	8	334	5	306	3.0e-54	206	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
647648399	235	32.02	10	234	2	228	1.0e-32	133	COG1802	DNA-binding transcriptional regulator, GntR family	230
647648400	517	30.5	1	516	15	555	1.0e-79	291	COG0747	ABC-type transport system, periplasmic component	556
647648401	318	46.2	1	316	6	315	6.0e-85	307	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647648402	265	51.32	1	263	25	289	7.0e-62	230	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647648403	540	55.33	1	529	3	535	0.0e+00	660	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
647648404	252	35.8	11	250	4	250	3.0e-37	148	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647648406	312	43.77	1	312	10	318	6.0e-41	161	COG0530	Ca2+/Na+ antiporter	320
647648408	328	36.33	1	307	3	309	2.0e-70	259	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
647648411	199	19.59	1	189	1	194	2.0e-07	48.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647648416	329	42.33	1	300	41	338	1.0e-84	306	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
647648417	463	53.96	9	458	6	442	3.0e-116	412	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
647648418	192	39.88	1	168	1	167	1.0e-27	116	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
647648423	364	32.42	16	341	1	323	2.0e-55	210	COG4644	Transposase and inactivated derivatives, TnpA family	323
647648424	233	39.8	9	204	5	199	6.0e-37	147	COG3316	Transposase (or an inactivated derivative)	215
647648425	605	24.66	90	603	43	549	4.0e-53	203	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647648426	271	29.72	31	253	3	249	5.0e-31	128	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647648427	416	32.2	1	257	3	264	3.0e-39	156	COG0673	Predicted dehydrogenase	342
647648428	309	34.85	39	294	15	277	5.0e-45	174	COG3386	Sugar lactone lactonase YvrE	307
647648431	413	24.04	4	363	2	333	6.0e-30	125	COG0644	Dehydrogenase (flavoprotein)	396
647648435	504	31.83	1	504	10	530	2.0e-79	289	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647648436	382	37.31	1	378	1	386	9.0e-62	230	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647648438	220	24.22	1	217	3	224	6.0e-21	94.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
647648439	368	26.91	5	366	10	381	7.0e-37	148	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647648440	227	24.78	5	226	4	224	2.0e-18	86	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
647648442	398	25.84	5	377	3	378	2.0e-35	144	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647648447	341	30.18	25	333	26	345	3.0e-34	139	COG3405	Endo-1,4-beta-D-glucanase Y	360
647648449	659	24.15	71	532	11	430	3.0e-46	180	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
647648454	255	30.58	58	255	46	246	2.0e-19	89.4	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
647648455	521	19.91	1	440	12	457	1.0e-13	71.6	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
647648456	236	34.18	4	235	2	224	4.0e-46	178	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
647648457	324	29.43	12	288	2	270	2.0e-38	152	COG1216	Glycosyltransferase, GT2 family	305
647648459	213	35.82	16	211	28	208	1.0e-20	93.3	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
647648461	415	21.13	52	400	35	381	1.0e-20	94.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647648462	140	56.15	6	135	4	133	1.0e-41	161	COG1780	Protein involved in ribonucleotide reduction	141
647648465	324	50.15	12	324	25	348	8.0e-100	357	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
647648469	406	30.52	1	402	5	385	5.0e-35	142	COG0475	Kef-type K+ transport system, membrane component KefB	397
647648472	457	25.39	24	457	29	464	9.0e-40	158	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
647648474	466	26.04	26	385	29	403	3.0e-35	143	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
647648476	389	17.94	19	387	20	381	4.0e-17	82.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647648477	472	22.55	11	360	44	398	3.0e-23	103	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
647648478	585	27.34	18	580	1	549	5.0e-60	226	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647648479	385	22.05	4	371	2	379	3.0e-33	136	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647648481	260	35.94	1	253	49	300	2.0e-45	176	COG3921	Uncharacterized conserved protein	300
647648482	316	24.52	117	316	25	230	4.0e-24	105	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
647648483	732	37.33	18	731	1	731	0.0e+00	508	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
647648484	328	37.99	1	322	1	278	1.0e-58	220	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
647648485	171	52.38	2	168	1	153	3.0e-52	197	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
647648486	532	19.37	232	514	8	283	9.0e-16	78.8	COG0668	Small-conductance mechanosensitive channel	316
647648490	619	37.91	10	618	31	638	1.0e-97	351	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
647648491	318	25.79	3	310	7	321	1.0e-35	143	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
647648492	300	33.9	6	295	1	288	2.0e-36	146	COG0583	DNA-binding transcriptional regulator, LysR family	297
647648497	302	37.74	31	292	11	264	1.0e-63	237	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
647648498	559	26.79	4	376	3	347	8.0e-38	152	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647648499	302	30.67	1	299	1	296	2.0e-33	136	COG0583	DNA-binding transcriptional regulator, LysR family	297
647648500	329	26.62	2	293	11	299	4.0e-35	141	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647648501	172	27.65	1	170	5	172	5.0e-17	81.1	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647648502	425	43.12	46	423	1	378	5.0e-83	301	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647648503	227	45.54	1	224	1	215	9.0e-54	203	COG3316	Transposase (or an inactivated derivative)	215
647648505	325	44.94	1	173	1	178	1.0e-43	170	COG4549	Uncharacterized protein YcnI	178
647648506	198	35.03	7	198	11	206	9.0e-36	143	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
647648507	240	30.54	1	236	7	237	1.0e-26	113	COG5343	Anti-sigma-K factor RskA	240
647648508	194	26.9	23	193	6	175	9.0e-22	96.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
647648515	460	35.85	89	247	2	157	5.0e-26	112	COG3436	Transposase	157
647648519	456	20.15	9	420	1	384	2.0e-19	90.8	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
647648520	295	21.89	13	290	42	334	2.0e-22	99.8	COG0687	Spermidine/putrescine-binding periplasmic protein	363
647648522	227	45.98	1	224	1	215	1.0e-54	206	COG3316	Transposase (or an inactivated derivative)	215
647648524	149	33.81	1	132	1	131	1.0e-19	89.2	COG1959	DNA-binding transcriptional regulator, IscR family	150
647648525	355	20.06	12	349	1	344	5.0e-14	72.2	COG2814	Predicted arabinose efflux permease, MFS family	394
647648527	297	25.32	1	294	2	300	7.0e-38	151	COG0492	Thioredoxin reductase	305
647648531	230	30.39	1	203	1	199	2.0e-17	82.6	COG0625	Glutathione S-transferase	211
647648533	227	45.98	1	224	1	215	1.0e-54	206	COG3316	Transposase (or an inactivated derivative)	215
647648535	362	23.6	25	360	1	326	4.0e-26	112	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
647648536	177	34.08	1	175	38	212	2.0e-35	142	COG1535	Isochorismate hydrolase	218
647648537	306	25.42	9	303	1	295	2.0e-24	106	COG0583	DNA-binding transcriptional regulator, LysR family	297
647648542	660	44.98	41	652	15	609	0.0e+00	537	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
647648544	612	21.55	316	589	2	296	3.0e-10	60.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
647648548	331	23.21	71	303	5	235	2.0e-16	79.9	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
647648549	422	25.18	116	395	1	257	2.0e-34	140	COG1192	Cellulose biosynthesis protein BcsQ	259
647648551	236	41.31	9	221	3	215	3.0e-45	175	COG3316	Transposase (or an inactivated derivative)	215
647648553	487	22.61	19	278	15	270	2.0e-32	134	COG4584	Transposase	278
647648554	252	42.69	1	250	2	254	7.0e-56	210	COG1484	DNA replication protein DnaC	254
647648559	246	27.23	1	231	7	239	2.0e-18	86.5	COG1414	DNA-binding transcriptional regulator, IclR family	246
647648560	199	31.35	3	172	2	185	4.0e-26	111	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
647648565	390	18.45	10	387	18	393	2.0e-21	97.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647648566	173	38.89	12	167	4	165	9.0e-32	129	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
647648568	288	44.25	1	283	20	298	1.0e-67	250	COG3246	Uncharacterized conserved protein, DUF849 family	298
647648571	266	25.13	69	259	36	221	2.0e-12	66.5	COG2801	Transposase InsO and inactivated derivatives	232
647648572	319	25.55	8	277	10	262	2.0e-17	83.2	COG4584	Transposase	278
647648573	294	28.14	12	294	9	301	3.0e-29	122	COG2215	ABC-type nickel/cobalt efflux system, permease component RcnA	303
647648574	200	28.08	2	197	22	213	3.0e-15	75.3	COG3683	ABC-type uncharacterized transport system, periplasmic component	213
647648575	408	20.27	27	389	18	348	7.0e-26	112	COG3177	Fic family protein	348
647648577	236	41.31	9	221	3	215	3.0e-45	175	COG3316	Transposase (or an inactivated derivative)	215
647648579	236	40.85	9	221	3	215	3.0e-44	171	COG3316	Transposase (or an inactivated derivative)	215
647648583	266	26.11	69	263	36	225	6.0e-14	71.6	COG2801	Transposase InsO and inactivated derivatives	232
647648588	189	34.88	16	100	1	86	3.0e-06	45.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
647648589	311	33.44	6	307	6	316	3.0e-52	199	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
647648590	394	31.38	17	390	3	393	8.0e-65	241	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
647648591	259	34.47	3	259	17	270	8.0e-36	144	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
647648592	458	24.23	3	445	7	409	2.0e-43	170	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647648593	221	39.29	5	221	6	229	3.0e-46	178	COG4215	ABC-type arginine transport system, permease component	230
647648594	231	49.09	1	219	1	220	2.0e-57	215	COG4160	ABC-type arginine/histidine transport system, permease component	228
647648595	248	62.92	7	246	2	240	2.0e-105	374	COG1126	ABC-type polar amino acid transport system, ATPase component	240
647648599	227	45.98	1	224	1	215	6.0e-55	207	COG3316	Transposase (or an inactivated derivative)	215
647648600	230	30.39	1	203	1	199	2.0e-17	82.6	COG0625	Glutathione S-transferase	211
647648601	291	32.3	5	284	1	287	3.0e-26	112	COG0583	DNA-binding transcriptional regulator, LysR family	297
