gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
645475473	542	44.59	2	542	120	635	0.0e+00	594	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
645475475	182	19.28	11	170	5	161	3.0e-08	51.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
645475477	327	60.82	114	307	4	195	6.0e-81	294	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
645475478	359	37.95	4	359	2	353	5.0e-75	274	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
645475483	267	25.83	5	146	5	143	8.0e-08	51.2	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
645475484	125	47.2	1	125	1	125	2.0e-36	144	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
645475488	262	32.52	19	258	2	246	3.0e-37	148	COG1381	Recombinational DNA repair protein (RecF pathway)	251
645475489	285	58.06	159	282	9	126	2.0e-27	116	COG3245	Cytochrome c5	126
645475492	397	58.33	1	396	1	396	0.0e+00	602	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
645475494	284	47.94	16	279	6	264	4.0e-75	274	COG0294	Dihydropteroate synthase	274
645475495	445	46.07	1	441	5	457	4.0e-116	411	COG1109	Phosphomannomutase	464
645475496	227	28.28	1	198	7	203	4.0e-35	141	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
645475497	333	27.49	2	331	16	349	3.0e-66	245	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
645475498	263	37.4	1	257	1	254	5.0e-65	241	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
645475500	219	46.73	6	214	5	213	2.0e-72	265	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
645475501	199	28.73	14	192	1	178	2.0e-14	72.4	COG0558	Phosphatidylglycerophosphate synthase	192
645475517	329	47.52	25	327	5	302	6.0e-89	321	COG4589	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase	303
645475518	380	52.97	28	378	1	337	1.0e-126	446	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
645475519	685	17.85	23	685	67	768	1.0e-33	138	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
645475521	444	31.18	147	423	42	316	3.0e-33	136	COG0642	Signal transduction histidine kinase	336
645475522	223	41.99	1	221	1	228	2.0e-54	205	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
645475524	497	43.92	15	497	1	483	0.0e+00	482	COG1530	Ribonuclease G or E	487
645475526	85	48.1	3	80	2	80	1.0e-19	88.1	COG0695	Glutaredoxin	80
645475527	144	54.68	1	139	5	142	8.0e-46	175	COG1952	Preprotein translocase subunit SecB	157
645475531	289	43.99	1	289	18	307	5.0e-80	290	COG1560	Lauroyl/myristoyl acyltransferase	308
645475532	156	50.67	5	153	3	151	1.0e-51	195	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
645475533	166	34.36	3	164	2	164	6.0e-35	140	COG1247	L-amino acid N-acyltransferase YncA	169
645475538	360	29.51	3	353	84	432	4.0e-76	278	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
645475540	215	35.48	1	215	3	217	4.0e-43	168	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
645475541	320	47.18	1	300	1	296	2.0e-75	276	COG1230	Co/Zn/Cd efflux system component	296
645475542	275	58.43	1	266	1	267	6.0e-108	383	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
645475543	207	37.14	1	207	1	210	5.0e-37	147	COG2834	Outer membrane lipoprotein-sorting protein	211
645475545	369	32.97	91	176	8	98	2.0e-17	83.4	COG3615	Uncharacterized protein/domain, possibly involved in tellurite resistance	99
645475546	1160	34.01	1	1158	1	1163	0.0e+00	674	COG1196	Chromosome segregation ATPase	1163
645475557	595	54.97	65	586	1	528	0.0e+00	514	COG4147	Na+(or H+)/acetate symporter ActP	529
645475558	120	32.29	14	109	8	102	2.0e-16	78	COG3162	Uncharacterized membrane protein, DUF485 family	102
645475559	298	27.61	1	294	1	294	5.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
645475560	235	40.44	4	222	15	233	2.0e-37	149	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
645475561	165	47.1	2	138	1	138	4.0e-35	140	COG2510	Uncharacterized membrane protein	140
645475564	409	23.45	4	364	23	360	4.0e-38	152	COG1373	Predicted ATPase, AAA+ superfamily	398
645475569	273	36.26	1	270	1	230	4.0e-46	178	COG3039	Transposase and inactivated derivatives, IS5 family	230
645475571	587	43.62	4	389	2	385	2.0e-66	247	COG0475	Kef-type K+ transport system, membrane component KefB	397
645475575	447	38.56	1	444	3	454	1.0e-112	399	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
645475585	162	36.84	48	141	1	95	4.0e-10	57.7	COG3335	Transposase	132
645475589	251	45.69	11	236	3	234	7.0e-74	270	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
645475590	190	50	2	95	1	93	2.0e-25	108	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
645475591	342	59.55	20	331	3	314	1.0e-117	416	COG0462	Phosphoribosylpyrophosphate synthetase	314
645475593	282	44.17	8	278	4	286	3.0e-83	301	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
645475594	196	25.73	1	196	5	206	5.0e-31	127	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
645475597	513	45.45	64	513	3	434	2.0e-108	386	COG0733	Na+-dependent transporter, SNF family	439
645475600	853	45.74	1	853	3	863	0.0e+00	938	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
645475602	470	62.45	13	470	1	458	0.0e+00	665	COG0165	Argininosuccinate lyase	459
645475604	248	31.21	84	229	40	189	5.0e-22	98.4	COG1525	Endonuclease YncB, thermonuclease family	192
645475608	243	29.57	1	221	1	226	3.0e-28	118	COG1587	Uroporphyrinogen-III synthase	248
645475609	510	36.22	42	429	2	391	2.0e-76	279	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
645475610	407	32.02	1	402	1	399	7.0e-84	304	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
645475611	353	54.67	1	351	2	352	8.0e-128	450	COG0407	Uroporphyrinogen-III decarboxylase	352
645475615	350	35.57	2	350	88	438	1.0e-63	237	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
645475620	178	43.75	1	176	1	169	3.0e-56	211	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
645475622	124	31.97	1	122	5	125	3.0e-22	97.3	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
645475624	435	50.75	1	323	1	333	6.0e-103	367	COG0460	Homoserine dehydrogenase	333
645475627	66	39.68	1	63	1	63	1.0e-10	58	COG2906	Bacterioferritin-associated ferredoxin	63
645475629	361	28.22	103	361	2	284	7.0e-22	98.6	COG1408	Predicted phosphohydrolase, MPP superfamily	284
645475630	302	40.68	1	302	22	343	2.0e-80	292	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
645475631	775	34.92	487	769	3	293	8.0e-57	215	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
645475633	80	62.69	14	80	1	67	3.0e-26	109	COG1278	Cold shock protein, CspA family	67
645475635	103	43.81	1	103	3	107	4.0e-29	119	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
645475636	761	45.05	1	750	1	786	0.0e+00	840	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
645475637	291	49.83	1	291	4	300	3.0e-92	331	COG4974	Site-specific recombinase XerD	300
645475639	175	51.41	36	175	13	154	4.0e-48	184	COG1225	Peroxiredoxin	157
645475640	211	28.97	4	201	5	215	2.0e-25	109	COG1428	Deoxyadenosine/deoxycytidine kinase	216
645475641	165	47.8	5	163	2	160	7.0e-49	186	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
645475642	124	44.8	1	120	1	124	2.0e-25	107	COG3094	Uncharacterized membrane protein SirB2	129
645475644	96	72.37	3	78	2	77	2.0e-26	110	COG1923	sRNA-binding regulator protein Hfq	77
645475646	535	47.86	51	489	2	444	0.0e+00	562	COG1160	Predicted GTPases	444
645475648	209	36.23	1	207	1	204	7.0e-36	143	COG2976	Putative negative regulator of RcsB-dependent stress response	207
645475649	431	50.11	2	430	1	429	0.0e+00	493	COG0124	Histidyl-tRNA synthetase	429
645475651	470	28.15	1	237	1	224	5.0e-38	152	COG0569	Trk K+ transport system, NAD-binding component	225
645475652	278	42.98	38	278	4	235	5.0e-40	158	COG3471	Predicted secreted (periplasmic) protein	235
645475653	278	56.84	1	278	1	285	7.0e-105	373	COG0414	Panthothenate synthetase	285
645475655	292	63.26	31	292	1	264	4.0e-104	371	COG0413	Ketopantoate hydroxymethyltransferase	268
645475658	263	24.91	1	261	1	280	1.0e-41	163	COG0421	Spermidine synthase	282
645475659	214	44.08	1	207	1	204	2.0e-57	215	COG2945	Alpha/beta superfamily hydrolase	210
645475660	590	30.89	224	589	38	418	2.0e-53	204	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
645475661	500	41.29	8	414	1	398	5.0e-96	345	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
645475662	459	63.48	1	456	1	455	0.0e+00	674	COG1066	Predicted ATP-dependent serine protease	456
645475663	328	28	7	328	1	311	2.0e-61	229	COG0039	Malate/lactate dehydrogenase	313
645475667	433	35.4	1	431	1	427	1.0e-96	347	COG1253	Hemolysin or related protein, contains CBS domains	429
645475669	377	26.28	236	369	6	142	9.0e-19	88.1	COG4639	Predicted kinase	168
645475670	445	49.42	9	441	3	431	3.0e-109	388	COG1114	Branched-chain amino acid permeases	431
645475672	295	43.72	38	277	1	247	3.0e-51	195	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
645475675	258	54.09	7	258	8	259	6.0e-92	330	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
645475677	154	36.13	1	151	4	154	2.0e-19	88.5	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
645475679	160	50.34	1	148	3	151	5.0e-51	193	COG1607	Acyl-CoA hydrolase	157
645475680	356	40.48	64	356	33	322	5.0e-63	235	COG0598	Mg2+ and Co2+ transporter CorA	322
645475681	316	50.48	4	313	3	302	2.0e-93	335	COG0492	Thioredoxin reductase	305
645475686	157	63.06	1	157	1	157	1.0e-51	195	COG2193	Bacterioferritin (cytochrome b1)	157
645475687	154	52.26	1	154	1	154	9.0e-48	182	COG2193	Bacterioferritin (cytochrome b1)	157
645475689	603	70.38	1	601	2	602	0.0e+00	1032	COG1217	Predicted membrane GTPase involved in stress response	603
645475692	463	21.11	20	359	32	382	1.0e-19	91.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
645475694	230	42.11	7	230	2	229	1.0e-30	126	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
645475699	1158	49.36	3	1157	3	1139	0.0e+00	1379	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
645475706	337	66.47	1	333	3	336	0.0e+00	541	COG0059	Ketol-acid reductoisomerase	338
645475707	75	45.95	2	74	24	97	6.0e-15	72.3	COG1359	Quinol monooxygenase YgiN	100
645475709	155	53.95	2	153	12	163	1.0e-45	175	COG0440	Acetolactate synthase, small subunit	163
645475712	330	22.65	7	287	25	325	2.0e-24	106	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
645475721	752	49.1	1	752	1	770	0.0e+00	949	COG1554	Trehalose and maltose hydrolase (possible phosphorylase)	772
645475722	221	32.29	3	220	2	220	8.0e-38	150	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
645475724	370	22.9	73	368	4	285	2.0e-15	77.3	COG0842	ABC-type multidrug transport system, permease component	286
645475727	230	56.09	1	230	1	230	2.0e-79	289	COG1794	Aspartate/glutamate racemase	230
645475729	116	35.04	1	115	1	103	2.0e-16	77.6	COG2315	Predicted DNA-binding protein with ?double-wing? structural motif, MmcQ/YjbR family	118
645475730	981	27.22	1	505	3	532	9.0e-71	262	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
645475733	256	54.84	16	256	2	249	1.0e-77	283	COG1496	Copper oxidase (laccase) domain	249
645475737	374	49.83	30	323	4	289	6.0e-87	314	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
645475738	268	43.77	2	266	1	254	2.0e-66	245	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
645475742	144	24.27	42	144	2	104	2.0e-09	55.3	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
645475744	839	27.26	4	836	20	716	1.0e-109	391	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
645475746	296	72.54	1	294	1	293	4.0e-121	427	COG0074	Succinyl-CoA synthetase, alpha subunit	293
645475747	388	60.67	1	388	1	386	0.0e+00	515	COG0045	Succinyl-CoA synthetase, beta subunit	387
645475749	477	49.15	1	467	2	454	0.0e+00	497	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
645475752	393	52.35	1	392	1	404	9.0e-113	400	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
645475753	964	56.64	24	964	1	906	0.0e+00	1300	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
645475754	427	54.48	27	427	2	390	0.0e+00	501	COG0372	Citrate synthase	390
645475755	82	46.25	1	80	7	86	3.0e-18	83.4	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
645475756	242	54.24	9	242	1	232	9.0e-82	296	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
645475757	587	53.38	5	573	4	562	0.0e+00	644	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
645475758	113	41.23	1	113	2	115	8.0e-20	89.1	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
645475761	132	38.68	21	126	5	105	2.0e-16	77.7	COG3339	Uncharacterized membrane protein YkvA, DUF1232 family	116
645475763	310	60.26	3	303	1	300	2.0e-118	419	COG0031	Cysteine synthase	300
645475765	283	51.43	4	282	1	272	4.0e-92	331	COG0253	Diaminopimelate epimerase	272
645475775	457	57.24	5	453	2	457	0.0e+00	616	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
645475778	218	29.33	6	214	6	229	2.0e-24	106	COG1011	FMN phosphatase YigB, HAD superfamily	229
645475779	333	41.33	1	333	3	336	3.0e-83	301	COG4143	ABC-type thiamine transport system, periplasmic component	336
645475784	617	35.74	26	607	1	567	7.0e-118	418	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
645475787	304	35.15	39	300	1	293	3.0e-48	185	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
645475790	168	64.2	1	162	1	161	4.0e-73	267	COG1854	S-ribosylhomocysteine lyase LuxS, autoinducer biosynthesis	161
645475793	107	50.94	2	105	1	106	1.0e-31	127	COG1965	Iron-binding protein CyaY, frataxin homolog	106
645475795	406	50	1	381	9	394	2.0e-120	425	COG0019	Diaminopimelate decarboxylase	394
645475797	150	33.78	1	146	1	139	2.0e-24	105	COG4968	Tfp pilus assembly protein PilE	139
645475804	416	50.37	1	393	1	377	4.0e-107	381	COG0459	Chaperonin GroEL (HSP60 family)	524
645475805	95	63.16	1	95	1	95	5.0e-32	129	COG0234	Co-chaperonin GroES (HSP10)	96
645475807	671	20.46	56	671	89	768	2.0e-31	131	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
645475814	283	60.14	4	279	1	276	5.0e-109	387	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
645475815	275	43.71	1	275	1	280	2.0e-65	242	COG2890	Methylase of polypeptide chain release factors	280
645475818	716	32.91	12	714	2	636	4.0e-121	429	COG1199	Rad3-related DNA helicase	654
645475823	612	50.98	1	612	1	597	0.0e+00	775	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
645475825	456	35.75	11	456	1	435	1.0e-113	403	COG0015	Adenylosuccinate lyase	438
645475826	224	30.35	20	217	10	202	1.0e-18	86.5	COG2949	Uncharacterized periplasmic protein SanA, affects membrane permeability for vancomycin	235
645475829	407	68.97	1	406	1	404	0.0e+00	508	COG3633	Na+/serine symporter	407
645475830	627	28.17	35	627	1	594	1.0e-102	367	COG0729	Outer membrane translocation and assembly module TamA	594
645475831	155	52.6	1	154	7	160	2.0e-47	181	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
645475833	201	69	1	200	1	200	2.0e-84	304	COG3560	Fatty acid repression mutant protein (predicted oxidoreductase)	200
645475834	133	37.4	7	130	10	139	4.0e-11	60.4	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
645475835	298	31.23	3	298	2	296	8.0e-37	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
645475836	135	38.83	3	101	25	127	1.0e-14	72	COG3794	Plastocyanin	128
645475837	255	36.19	1	253	2	258	1.0e-55	210	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
645475838	407	26.59	14	338	25	319	1.0e-33	137	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
645475839	348	39.1	18	348	2	330	2.0e-47	183	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
645475843	371	28.36	6	341	15	319	1.0e-36	147	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
645475849	322	45.79	8	321	22	340	1.0e-90	326	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
645475850	239	67.62	1	210	61	270	5.0e-95	340	COG2326	Polyphosphate kinase 2, PPK2 family	270
645475852	636	33.76	52	431	131	462	9.0e-84	305	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
645475854	591	24.42	1	591	8	556	1.0e-62	234	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
645475855	429	27.3	33	304	15	296	8.0e-40	158	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
645475856	200	35.92	6	199	4	205	5.0e-33	134	COG0655	Multimeric flavodoxin WrbA	207
645475857	266	27.09	19	266	7	257	1.0e-08	54.2	COG0730	Uncharacterized membrane protein YfcA	258
645475869	74	40.85	1	71	5	75	6.0e-07	45.7	COG1722	Exonuclease VII small subunit	81
645475870	298	36.94	5	298	1	322	1.0e-61	230	COG0142	Geranylgeranyl pyrophosphate synthase	322
645475873	487	64.21	6	479	2	473	0.0e+00	819	COG0362	6-phosphogluconate dehydrogenase	473
645475875	589	45.57	52	589	12	539	0.0e+00	572	COG0405	Gamma-glutamyltranspeptidase	539
645475877	304	59.08	1	303	2	300	1.0e-124	439	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
645475879	334	59.7	3	331	2	331	5.0e-129	454	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
645475881	176	22.15	18	173	2	147	7.0e-23	100	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
645475882	224	51.9	1	158	3	154	7.0e-47	180	COG1720	tRNA (Thr-GGU) A37 N-methylase	156
645475884	211	27.14	5	207	9	202	2.0e-21	96	COG1335	Nicotinamidase-related amidase	205
645475885	326	34.08	1	307	2	306	6.0e-62	231	COG0859	ADP-heptose:LPS heptosyltransferase	334
645475886	249	48.08	1	249	1	260	6.0e-66	244	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
645475887	311	53.94	1	311	1	312	1.0e-88	319	COG2025	Electron transfer flavoprotein, alpha subunit	313
645475888	203	34.98	2	202	1	203	2.0e-45	175	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
645475890	444	61.74	22	444	1	425	0.0e+00	619	COG0151	Phosphoribosylamine-glycine ligase	428
645475891	199	36.98	10	199	4	194	2.0e-41	162	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
645475898	151	41.04	11	143	12	142	3.0e-17	81.6	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
645475900	280	65.71	1	279	2	279	4.0e-108	384	COG3220	Uncharacterized conserved protein, UPF0276 family	282
645475901	233	53.68	7	230	5	235	2.0e-65	242	COG3219	Uncharacterized protein	237
645475903	196	29.89	8	191	18	182	1.0e-21	96.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
645475908	180	49.04	74	177	23	126	6.0e-18	84	COG3245	Cytochrome c5	126
645475914	595	43.28	3	574	1	567	0.0e+00	635	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
645475915	89	50	1	88	1	88	5.0e-24	102	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
645475916	145	28.97	1	143	1	143	4.0e-23	100	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
645475918	187	36.42	14	186	4	176	9.0e-56	209	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
645475923	268	22.78	7	268	107	420	8.0e-36	144	COG1793	ATP-dependent DNA ligase	444
645475924	248	35.78	38	248	9	226	5.0e-30	124	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
645475926	589	32.62	35	450	7	387	3.0e-63	236	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
645475930	248	23.55	8	247	24	282	8.0e-16	77.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
645475931	268	38.91	11	248	2	225	5.0e-47	181	COG1040	Predicted amidophosphoribosyltransferases	225
645475932	154	64.52	1	154	2	155	1.0e-64	238	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
645475935	110	73.21	1	110	1	112	3.0e-43	166	COG2824	Uncharacterized Zn-ribbon-containing protein	112
645475938	480	56	164	480	16	340	3.0e-106	379	COG0552	Signal recognition particle GTPase	340
645475943	249	39	1	235	1	233	3.0e-57	215	COG3967	Short-chain dehydrogenase involved in D-alanine esterification of teichoic acids	245
645475949	281	35.79	167	260	1	95	5.0e-09	55.4	COG3335	Transposase	132
645475950	253	42.35	5	250	1	251	2.0e-38	153	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
645475951	191	31.22	6	191	5	184	2.0e-25	109	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
645475953	681	15.84	1	681	6	768	3.0e-29	123	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
645475961	473	23.82	26	469	2	424	3.0e-55	210	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
645475964	447	78.08	1	447	1	447	0.0e+00	749	COG1726	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA	447
645475965	410	73.09	2	405	1	400	0.0e+00	531	COG1805	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB	400
645475966	258	66.41	1	258	1	262	9.0e-106	376	COG2869	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC	264
645475967	208	80.77	1	208	1	208	5.0e-94	336	COG1347	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD	208
645475968	197	83.33	1	197	1	198	2.0e-79	288	COG2209	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE	198
645475969	405	88.21	1	405	4	410	0.0e+00	779	COG2871	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF	410
645475971	1201	56.09	438	1199	1	768	0.0e+00	1017	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
645475972	508	49.7	1	489	2	486	2.0e-91	330	COG0591	Na+/proline symporter	493
645475975	358	24.18	53	356	1	253	7.0e-35	141	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
645475976	479	32.47	5	460	3	465	2.0e-90	326	COG2027	D-alanyl-D-alanine carboxypeptidase	470
645475978	135	22.7	1	125	1	138	2.0e-13	68.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
645475979	213	23.81	6	208	4	211	8.0e-23	100	COG0625	Glutathione S-transferase	211
645475980	213	25.71	6	208	4	211	2.0e-25	109	COG0625	Glutathione S-transferase	211
645475981	172	36.26	1	171	2	183	3.0e-32	131	COG3009	Uncharacterized lipoprotein YmbA	190
645475982	553	43.19	5	553	3	552	0.0e+00	594	COG3008	Paraquat-inducible protein B	553
645475983	401	40.57	2	386	29	409	3.0e-107	381	COG2995	Uncharacterized paraquat-inducible protein A	418
645475985	207	60.42	3	191	5	196	4.0e-64	237	COG3230	Heme oxygenase	196
645475986	792	21.35	1	792	10	768	9.0e-49	188	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
645475989	256	34.14	22	255	38	286	2.0e-47	182	COG3176	Putative hemolysin	292
645475990	249	30.37	5	188	1	188	6.0e-24	104	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
645475991	268	56.32	9	268	7	263	7.0e-98	350	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
645475992	139	47.76	1	134	2	134	1.0e-35	142	COG1765	Uncharacterized OsmC-related protein	137
645475994	238	28.89	9	233	1	220	1.0e-30	126	COG1802	DNA-binding transcriptional regulator, GntR family	230
645475996	258	34.13	4	254	3	253	3.0e-58	218	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
645475999	562	32.83	21	538	1	472	8.0e-103	368	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
645476000	300	25	14	138	12	135	4.0e-06	46	COG2510	Uncharacterized membrane protein	140
645476003	221	42.29	31	205	1	169	3.0e-50	192	COG3663	G:T/U-mismatch repair DNA glycosylase	169
645476005	400	67.85	5	399	1	393	0.0e+00	676	COG0133	Tryptophan synthase beta chain	396
645476008	431	44.92	5	428	1	443	0.0e+00	540	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
645476009	222	42.71	1	190	1	188	6.0e-55	207	COG0132	Dethiobiotin synthetase	223
645476016	191	30.34	39	177	28	169	1.0e-12	66.5	COG3161	4-hydroxybenzoate synthetase (chorismate-pyruvate lyase)	174
645476017	305	41.64	18	297	9	289	8.0e-49	187	COG0382	4-hydroxybenzoate polyprenyltransferase	289
645476019	149	39.6	3	149	1	149	4.0e-30	124	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
645476020	320	44.73	2	313	1	307	2.0e-89	322	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
645476021	284	50.7	1	280	1	285	1.0e-103	369	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
645476024	313	38.78	1	301	12	322	2.0e-65	243	COG1161	Ribosome biogenesis GTPase A	322
645476025	200	51.11	1	179	3	180	4.0e-44	170	COG1386	Chromosome segregation and condensation protein ScpB	184
645476027	553	44.82	1	553	1	557	0.0e+00	535	COG0497	DNA repair ATPase RecN	557
645476028	329	38.91	12	328	1	316	1.0e-66	246	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
645476029	130	52.14	10	126	2	118	5.0e-29	119	COG0818	Diacylglycerol kinase	123
645476030	181	52	23	170	3	151	1.0e-39	155	COG2847	Copper(I)-binding protein	151
645476033	449	50.34	10	442	6	437	0.0e+00	485	COG1570	Exonuclease VII, large subunit	440
645476035	334	27.78	1	334	1	313	8.0e-40	157	COG0451	Nucleoside-diphosphate-sugar epimerase	314
645476039	246	49.79	14	246	11	239	9.0e-67	246	COG0284	Orotidine-5'-phosphate decarboxylase	240
645476041	215	44.95	1	214	1	178	2.0e-48	185	COG0563	Adenylate kinase or related kinase	178
645476043	253	58.89	1	253	1	245	1.0e-93	336	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
645476044	60	56.67	1	60	1	60	3.0e-18	83.7	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
645476046	202	29.38	13	189	4	174	1.0e-14	73.5	COG3184	Uncharacterized protein	183
645476047	178	26.14	3	178	5	172	9.0e-13	66.6	COG3184	Uncharacterized protein	183
645476048	341	46.49	4	337	1	331	3.0e-88	318	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
645476052	358	70.44	1	358	1	362	0.0e+00	558	COG0216	Protein chain release factor A	363
645476056	422	27.23	1	418	3	415	2.0e-48	186	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
645476057	112	73.21	1	112	1	112	2.0e-38	150	COG0347	Nitrogen regulatory protein PII	112
645476058	216	24.09	1	216	3	207	7.0e-21	94.3	COG0778	Nitroreductase	207
645476060	262	52.42	9	253	2	249	5.0e-64	237	COG0805	Sec-independent protein secretion pathway component TatC	255
645476061	224	34.44	1	90	1	90	9.0e-16	77.3	COG1826	Sec-independent protein translocase protein TatA	94
645476062	67	35.29	1	67	1	68	5.0e-11	59.6	COG1826	Sec-independent protein translocase protein TatA	94
645476063	107	50	2	104	1	103	6.0e-26	108	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
645476064	107	53.85	6	96	1	91	6.0e-24	102	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
645476066	135	61.47	4	112	3	111	2.0e-44	171	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
645476067	255	70.87	3	255	2	255	3.0e-112	397	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
645476071	245	54.13	1	242	2	239	3.0e-84	304	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
645476076	419	72.08	1	419	4	421	0.0e+00	720	COG1158	Transcription termination factor Rho	422
645476089	143	45.14	1	143	1	144	6.0e-45	173	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
645476090	91	50	1	90	3	92	1.0e-27	114	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
645476091	192	55.85	5	192	2	189	4.0e-74	270	COG0193	Peptidyl-tRNA hydrolase	190
645476096	233	37.22	1	222	1	218	1.0e-58	219	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
645476097	484	49.79	9	474	1	459	0.0e+00	617	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
645476099	335	37	63	332	1	230	1.0e-42	167	COG3039	Transposase and inactivated derivatives, IS5 family	230
645476101	260	55.6	1	249	83	330	4.0e-86	311	COG0502	Biotin synthase or related enzyme	335
645476104	218	36.11	1	216	1	203	4.0e-33	134	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
645476105	387	40.74	10	375	5	381	2.0e-80	293	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
645476106	679	36.03	32	639	16	598	4.0e-128	452	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
645476107	167	33.56	15	159	11	156	1.0e-12	66.4	COG2891	Cell shape-determining protein MreD	167
645476108	279	28.31	11	279	4	275	2.0e-40	159	COG1792	Cell shape-determining protein MreC	284
645476109	329	58.57	1	318	13	332	3.0e-107	381	COG1077	Actin-like ATPase involved in cell morphogenesis	342
645476110	96	44.79	1	96	1	96	3.0e-20	90.3	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
645476112	482	51.22	1	481	4	474	0.0e+00	518	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
645476118	290	40	5	288	11	299	4.0e-75	274	COG2990	Uncharacterized protein VirK/YbjX	300
645476119	476	58.37	1	476	4	481	0.0e+00	694	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
645476120	189	29.73	1	174	2	183	1.0e-10	59.4	COG0693	Putative intracellular protease/amidase	188
645476124	335	38.21	112	323	20	219	2.0e-47	183	COG0543	NAD(P)H-flavin reductase	252
645476125	164	46.03	41	164	12	137	2.0e-29	121	COG3439	Uncharacterized conserved protein, DUF302 family	137
645476126	118	33.98	18	118	3	105	3.0e-15	74.2	COG0607	Rhodanese-related sulfurtransferase	110
645476127	111	39.8	11	107	19	116	1.0e-12	65	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
645476129	281	49.82	2	276	1	273	7.0e-97	347	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
645476131	324	52.29	1	324	1	324	5.0e-119	420	COG0158	Fructose-1,6-bisphosphatase	326
645476132	296	53.18	28	292	2	264	1.0e-81	296	COG0548	Acetylglutamate kinase	265
645476134	376	42.56	5	376	1	372	3.0e-81	295	COG2866	Murein tripeptide amidase MpaA	374
645476135	284	46.02	1	282	5	278	2.0e-68	252	COG0682	Prolipoprotein diacylglyceryltransferase	287
645476138	226	38.03	1	222	12	245	2.0e-54	205	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
645476139	404	39.26	8	403	1	393	3.0e-100	358	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
645476141	416	67.32	7	415	6	413	0.0e+00	664	COG0112	Glycine/serine hydroxymethyltransferase	413
645476143	385	35.92	1	385	4	390	2.0e-60	226	COG2814	Predicted arabinose efflux permease, MFS family	394
645476147	501	19.15	3	393	1	418	4.0e-27	116	COG3182	Uncharacterized iron-regulated membrane protein	442
645476155	212	37.13	12	212	1	202	9.0e-37	146	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
645476158	222	33.94	1	218	4	202	7.0e-45	173	COG0560	Phosphoserine phosphatase	212
645476161	106	41.18	6	106	3	104	1.0e-24	104	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
645476162	149	74.6	24	149	1	126	2.0e-55	207	COG0853	Aspartate 1-decarboxylase	126
645476163	280	59.57	3	279	5	279	4.0e-124	437	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
645476167	278	34.83	1	264	1	264	4.0e-59	221	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
645476168	282	35.62	8	282	9	314	1.0e-57	216	COG0627	S-formylglutathione hydrolase FrmB	316
645476170	570	45.44	1	566	1	500	0.0e+00	570	COG0442	Prolyl-tRNA synthetase	500
645476172	227	34.51	115	226	9	121	2.0e-19	89.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
645476173	321	39.27	7	321	6	335	4.0e-84	304	COG3938	Proline racemase	341
645476174	417	26.24	9	416	8	382	4.0e-35	142	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
645476175	298	38.95	10	292	1	285	2.0e-70	259	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
645476176	489	45.02	27	486	11	466	0.0e+00	474	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
645476177	483	44.95	1	457	4	452	2.0e-121	429	COG1115	Na+/alanine symporter	452
645476179	305	26.67	5	293	1	299	6.0e-47	181	COG0826	Collagenase-like protease, PrtC family	347
645476180	335	38.82	1	335	3	312	1.0e-79	290	COG0826	Collagenase-like protease, PrtC family	347
645476184	198	28.79	1	198	47	231	1.0e-16	79.6	COG2801	Transposase InsO and inactivated derivatives	232
645476186	443	16.09	51	436	59	434	1.0e-06	48.3	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
645476187	345	35.43	2	345	1	333	5.0e-67	248	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
645476188	542	45.12	43	530	3	446	0.0e+00	464	COG0166	Glucose-6-phosphate isomerase	446
645476190	242	61.41	1	240	1	240	2.0e-96	345	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
645476193	472	51.74	2	457	1	451	0.0e+00	485	COG1115	Na+/alanine symporter	452
645476194	531	69.51	1	527	1	528	0.0e+00	889	COG4108	Peptide chain release factor RF-3	528
645476200	310	35.67	12	310	1	303	1.0e-66	246	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
645476211	599	37.9	89	329	3	236	1.0e-49	191	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
645476217	91	53.42	16	88	1	73	3.0e-20	89.9	COG2501	Ribosome-associated protein YbcJ, S4-like RNA binding protein	73
645476219	278	45.14	1	256	3	255	8.0e-61	227	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
645476223	366	50.27	1	366	2	370	7.0e-114	403	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
645476226	1144	46.43	3	1137	1	1135	0.0e+00	1246	COG0587	DNA polymerase III, alpha subunit	1139
645476228	236	33.33	1	235	3	225	3.0e-52	198	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
645476229	196	40.93	4	195	2	191	6.0e-52	196	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
645476230	166	27.68	1	165	4	175	3.0e-20	91.2	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
645476231	59	49.12	1	56	1	57	1.0e-12	64.5	COG0333	Ribosomal protein L32	57
645476232	201	33.33	27	196	1	188	7.0e-35	140	COG2236	Hypoxanthine phosphoribosyltransferase	192
645476234	357	50.3	1	332	1	333	3.0e-112	398	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
645476236	472	41.18	16	469	1	455	5.0e-71	262	COG1538	Outer membrane protein TolC	457
645476239	430	36.49	38	392	25	372	3.0e-30	126	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
645476240	211	24.26	1	202	3	201	2.0e-14	73.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
645476241	558	46.52	4	540	1	530	0.0e+00	576	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
645476242	514	50.89	1	501	1	495	0.0e+00	601	COG0029	Aspartate oxidase	518
645476243	381	50.93	48	367	16	324	9.0e-115	407	COG0379	Quinolinate synthase	324
645476244	326	64.6	8	326	2	322	0.0e+00	474	COG4111	Uncharacterized conserved protein	322
645476245	276	52	1	275	9	278	3.0e-93	334	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
645476248	269	40.15	5	268	7	279	4.0e-70	258	COG0169	Shikimate 5-dehydrogenase	283
645476251	472	51.05	1	472	1	443	0.0e+00	524	COG0174	Glutamine synthetase	443
645476256	172	44.97	1	166	3	167	3.0e-37	148	COG0597	Lipoprotein signal peptidase	167
645476257	322	65.19	4	296	2	294	2.0e-122	431	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
645476258	248	49.8	5	246	2	251	4.0e-52	198	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
645476263	1239	20.25	851	1237	2	381	5.0e-17	84.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
645476263	1239	29.72	7	216	2	206	2.0e-19	92.1	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
645476265	617	33.9	16	608	2	560	2.0e-122	433	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
645476267	308	55.02	1	307	2	310	1.0e-93	336	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
645476268	429	30.93	324	420	8	94	4.0e-17	83	COG3326	Uncharacterized membrane protein YsdA, DUF1294 family	94
645476272	320	58.2	1	320	1	322	2.0e-119	422	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
645476273	241	39.59	1	239	3	246	3.0e-65	241	COG1385	16S rRNA U1498 N3-methylase RsmE	246
645476274	290	32.68	39	286	15	260	2.0e-54	205	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
645476277	298	29.18	38	294	1	248	7.0e-45	174	COG2876	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	286
645476279	708	20.31	12	702	5	642	6.0e-48	185	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
645476281	737	33.69	3	735	12	717	0.0e+00	466	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
645476282	198	29.29	1	198	47	231	3.0e-18	85	COG2801	Transposase InsO and inactivated derivatives	232
645476290	219	27.07	1	170	3	165	2.0e-18	86.2	COG4186	Calcineurin-like phosphoesterase superfamily protein	186
645476293	487	20.7	1	486	199	665	0.0e+00	531	COG4688	Uncharacterized protein	665
645476298	169	40.23	1	169	3	167	4.0e-36	144	COG0629	Single-stranded DNA-binding protein	167
645476299	460	22.13	32	393	30	385	3.0e-23	103	COG2814	Predicted arabinose efflux permease, MFS family	394
645476302	502	41.28	5	493	1	492	2.0e-126	445	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
645476305	162	36.84	48	141	1	95	1.0e-09	56.6	COG3335	Transposase	132
645476319	208	49.51	1	205	1	206	4.0e-61	227	COG0125	Thymidylate kinase	208
645476320	426	55.76	1	424	13	422	0.0e+00	569	COG0281	Malic enzyme	432
645476321	379	41.58	1	375	54	424	5.0e-106	378	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
645476324	108	49.52	1	105	2	106	6.0e-30	122	COG4551	Predicted protein tyrosine phosphatase	109
645476327	437	58.2	3	431	4	433	0.0e+00	603	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
645476332	470	33.05	1	467	1	411	3.0e-101	362	COG0498	Threonine synthase	411
645476333	258	35.45	1	255	2	266	1.0e-55	209	COG1018	Ferredoxin-NADP reductase	266
645476338	675	65.87	8	674	2	663	0.0e+00	1079	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
645476340	445	53.44	1	436	7	435	0.0e+00	551	COG0305	Replicative DNA helicase	435
645476341	231	27.96	3	213	5	175	1.0e-25	109	COG4970	Tfp pilus assembly protein FimT	181
645476342	208	27.61	1	162	12	152	4.0e-18	85	COG4967	Tfp pilus assembly protein PilV	162
645476343	325	27.22	14	325	11	318	7.0e-34	138	COG4966	Tfp pilus assembly protein PilW	318
645476344	204	32.47	15	203	11	192	3.0e-26	111	COG4726	Tfp pilus assembly protein PilX	196
645476349	378	66.94	10	378	1	366	0.0e+00	566	COG1062	Zn-dependent alcohol dehydrogenase	366
645476350	275	40.39	1	275	7	313	1.0e-75	276	COG0627	S-formylglutathione hydrolase FrmB	316
645476352	319	36.33	13	265	1	249	5.0e-52	198	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
645476353	92	38.04	1	92	24	115	5.0e-18	82.7	COG2919	Cell division protein FtsB	117
645476354	428	68.78	1	426	1	423	0.0e+00	665	COG0148	Enolase	423
645476360	487	30.32	257	477	1	170	1.0e-34	141	COG0516	IMP dehydrogenase/GMP reductase	170
645476363	286	37.55	50	278	32	276	1.0e-34	140	COG0790	TPR repeat	292
645476364	282	47.16	1	280	7	287	3.0e-72	264	COG1562	Phytoene/squalene synthetase	288
645476365	447	33.85	1	433	2	442	5.0e-95	341	COG2907	Predicted NAD/FAD-binding protein	447
645476368	393	57	2	393	14	401	0.0e+00	549	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
645476369	887	69.67	1	883	2	883	0.0e+00	1427	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
645476373	595	50.97	118	579	4	454	0.0e+00	482	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
645476375	235	46.46	15	235	1	226	2.0e-65	242	COG0220	tRNA G46 methylase TrmB	227
645476376	209	42.72	1	205	1	198	5.0e-63	233	COG0307	Riboflavin synthase alpha chain	204
645476379	142	21.37	11	141	14	143	7.0e-12	63.4	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
645476380	227	63.23	4	226	3	220	2.0e-87	315	COG0036	Pentose-5-phosphate-3-epimerase	220
645476381	343	71.52	14	343	3	331	0.0e+00	540	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
645476384	418	35.15	4	401	19	411	4.0e-81	295	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
645476386	319	41.43	3	246	1	251	2.0e-41	163	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
645476387	135	18.8	4	133	8	138	6.0e-09	53.4	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
645476389	219	64.38	1	219	4	222	4.0e-104	370	COG0692	Uracil DNA glycosylase	223
645476390	165	34.71	1	163	14	171	8.0e-34	136	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
645476391	328	64.5	15	319	1	306	0.0e+00	497	COG0320	Lipoate synthase	306
645476392	205	57.49	1	205	11	216	5.0e-78	284	COG0321	Lipoate-protein ligase B	221
645476393	88	41.86	2	87	4	89	5.0e-25	106	COG2921	Putative lipoic acid-binding regulatory protein	90
645476395	820	64.86	5	795	1	780	0.0e+00	1173	COG0466	ATP-dependent Lon protease, bacterial type	782
645476396	89	61.8	1	89	2	90	1.0e-25	107	COG0776	Bacterial nucleoid DNA-binding protein	94
645476397	177	47.7	2	175	1	171	1.0e-48	186	COG0221	Inorganic pyrophosphatase	171
645476398	305	35.78	1	301	5	314	4.0e-66	244	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
645476399	271	44.62	11	270	1	239	2.0e-70	259	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
645476401	261	48.08	1	258	1	260	2.0e-73	269	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
645476403	433	16.96	43	421	41	441	4.0e-18	86.4	COG1538	Outer membrane protein TolC	457
645476404	727	32.85	8	700	18	697	0.0e+00	498	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
645476405	408	21.39	17	386	6	341	4.0e-19	89.6	COG1566	Multidrug resistance efflux pump	352
645476411	759	35.65	43	753	1	654	0.0e+00	598	COG0209	Ribonucleotide reductase alpha subunit	696
645476413	377	37.07	3	373	2	347	1.0e-90	326	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
645476414	100	40.24	8	81	14	95	5.0e-12	62.8	COG0633	Ferredoxin	102
645476419	535	27.22	14	518	1	470	2.0e-69	257	COG5339	Uncharacterized conserved protein YdgA, DUF945 family	479
645476422	255	36.8	19	247	14	238	3.0e-39	155	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
645476423	228	46.55	1	226	1	227	2.0e-57	215	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
645476424	159	65.61	3	159	1	157	2.0e-62	231	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
645476425	223	51.77	3	220	2	227	8.0e-70	256	COG0120	Ribose 5-phosphate isomerase	227
645476426	293	49.83	6	293	1	290	3.0e-79	288	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
645476428	381	41.32	6	381	1	363	4.0e-89	322	COG0687	Spermidine/putrescine-binding periplasmic protein	363
645476430	874	58.09	1	873	6	879	0.0e+00	1166	COG0013	Alanyl-tRNA synthetase	879
645476436	534	41.76	1	532	11	528	0.0e+00	569	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
645476439	240	33.76	58	207	32	187	3.0e-23	102	COG4122	Predicted O-methyltransferase YrrM	219
645476440	472	42.92	15	472	7	458	0.0e+00	475	COG0773	UDP-N-acetylmuramate-alanine ligase	459
645476442	622	40.35	1	621	1	653	0.0e+00	533	COG0370	Fe2+ transport system protein B	653
645476443	88	26.58	4	82	1	70	3.0e-06	43.3	COG1918	Fe2+ transport system protein FeoA	75
645476445	209	38.05	1	202	1	203	2.0e-42	165	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
645476446	120	40.48	1	120	1	126	1.0e-16	78.7	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
645476448	311	33.76	3	309	1	309	2.0e-81	296	COG0167	Dihydroorotate dehydrogenase	310
645476449	380	49.46	12	378	2	366	0.0e+00	464	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
645476452	177	33.33	1	177	1	184	1.0e-34	139	COG2840	DNA-nicking endonuclease, Smr domain	184
645476454	455	38.83	20	455	16	457	5.0e-96	344	COG0277	FAD/FMN-containing dehydrogenase	459
645476456	159	45.12	1	159	1	161	8.0e-36	143	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
645476460	605	53.49	2	603	24	575	0.0e+00	784	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
645476463	272	37.22	8	271	6	260	7.0e-48	184	COG3878	Uncharacterized protein YwqG	261
645476465	129	53.91	1	127	2	128	3.0e-31	127	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
645476469	391	45.67	17	391	34	410	1.0e-116	413	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
645476474	1103	16.12	514	1103	203	768	5.0e-16	80.7	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
645476475	197	45.64	4	197	3	193	7.0e-61	226	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
645476480	296	45.7	6	293	1	281	2.0e-70	259	COG0061	NAD kinase	281
645476481	190	30.96	1	189	8	204	1.0e-28	119	COG3165	Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain	204
645476482	269	21.8	16	251	8	266	8.0e-19	87.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
645476483	216	22.61	1	196	3	201	1.0e-12	66.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
645476484	346	35.38	4	343	3	289	2.0e-79	289	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
645476485	257	29.56	2	251	6	259	5.0e-30	124	COG3680	Uncharacterized protein	259
645476486	459	31.64	13	445	12	440	3.0e-67	249	COG0534	Na+-driven multidrug efflux pump	455
645476493	396	44.01	24	356	11	343	1.0e-81	296	COG1566	Multidrug resistance efflux pump	352
645476494	466	28.41	15	466	1	449	7.0e-42	165	COG1538	Outer membrane protein TolC	457
645476495	164	27.35	48	164	15	126	2.0e-09	54.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
645476498	227	44.8	1	215	14	233	8.0e-44	170	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
645476500	148	60.81	2	148	1	148	2.0e-36	145	COG2707	Uncharacterized membrane protein, DUF441 family	151
645476501	324	38.27	8	324	3	322	6.0e-81	294	COG0142	Geranylgeranyl pyrophosphate synthase	322
645476503	116	59.8	15	116	1	102	6.0e-34	135	COG0261	Ribosomal protein L21	103
645476504	90	72.09	1	86	1	85	1.0e-30	124	COG0211	Ribosomal protein L27	87
645476506	394	32.91	4	394	2	384	9.0e-71	261	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
645476507	896	45.05	1	895	44	960	0.0e+00	997	COG1391	Glutamine synthetase adenylyltransferase	963
645476509	531	16.38	30	346	6	343	7.0e-16	79	COG0515	Serine/threonine protein kinase	384
645476511	244	69.29	6	244	3	243	1.0e-109	389	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
645476512	176	39.53	6	176	8	169	1.0e-30	126	COG1934	Lipopolysaccharide export system protein LptA	173
645476513	193	34.2	1	193	2	187	3.0e-41	161	COG3117	Lipopolysaccharide export system protein LptC	188
645476514	178	57.65	8	177	1	170	2.0e-65	242	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
645476515	324	59.2	7	206	1	201	7.0e-69	254	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
645476516	351	27.06	9	308	1	224	5.0e-34	138	COG0176	Transaldolase	239
645476520	162	36.08	5	100	4	100	2.0e-11	62.3	COG4969	Tfp pilus assembly protein, major pilin PilA	125
645476521	146	30.43	1	90	2	93	2.0e-10	58.4	COG4969	Tfp pilus assembly protein, major pilin PilA	125
645476523	164	37.5	1	136	2	136	4.0e-30	124	COG1943	REP element-mobilizing transposase RayT	136
645476526	736	42.43	12	655	1	652	0.0e+00	575	COG0210	Superfamily I DNA or RNA helicase	655
645476527	316	31.63	22	314	3	292	2.0e-49	189	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
645476528	130	60	1	130	1	130	2.0e-45	174	COG0103	Ribosomal protein S9	130
645476529	143	65.28	1	143	1	144	5.0e-54	203	COG0102	Ribosomal protein L13	148
645476530	100	32.65	3	100	1	98	6.0e-14	69.2	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
645476532	329	48.94	1	329	2	329	1.0e-111	396	COG0240	Glycerol-3-phosphate dehydrogenase	329
645476537	450	42.13	1	447	2	441	9.0e-112	397	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
645476538	104	47.17	1	104	1	106	4.0e-18	83	COG1544	Ribosome-associated translation inhibitor RaiA	110
645476541	82	38.16	1	75	1	76	6.0e-06	42.3	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
645476547	145	28.95	26	139	12	125	6.0e-10	56.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
645476548	166	28.21	12	165	9	162	4.0e-29	121	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
645476550	359	42.54	47	311	10	264	9.0e-60	224	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
645476553	157	23.68	16	123	3	114	1.0e-20	92.8	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
645476554	559	47.23	61	559	5	500	0.0e+00	557	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
645476555	413	41.21	18	413	2	397	2.0e-110	392	COG1459	Type II secretory pathway, component PulF	397
645476556	287	44.53	15	283	6	254	2.0e-33	136	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
645476557	209	37.06	1	197	1	195	3.0e-42	165	COG0237	Dephospho-CoA kinase	201
645476558	68	60.34	7	64	1	58	7.0e-17	78.9	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
645476560	283	18.22	18	273	50	279	1.0e-10	60.7	COG0668	Small-conductance mechanosensitive channel	316
645476562	678	57.86	1	676	7	683	0.0e+00	879	COG0339	Zn-dependent oligopeptidase	683
645476564	461	43.78	12	461	2	442	1.0e-86	314	COG2610	H+/gluconate symporter or related permease	442
645476565	172	45.68	8	169	1	160	2.0e-56	211	COG3265	Gluconate kinase	161
645476569	247	37.55	1	239	1	250	2.0e-55	209	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
645476570	310	42.76	29	309	42	331	2.0e-41	163	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
645476571	262	35.82	7	260	27	294	7.0e-53	200	COG4558	ABC-type hemin transport system, periplasmic component	300
645476574	826	47	2	818	106	931	0.0e+00	995	COG0060	Isoleucyl-tRNA synthetase	933
645476578	306	45.96	33	300	1	270	1.0e-74	273	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
645476580	364	21.18	161	363	71	261	2.0e-08	53.9	COG3087	Cell division protein FtsN	264
645476583	498	58.61	15	496	1	486	0.0e+00	618	COG0606	Predicted ATPase with chaperone activity	490
645476584	106	44	1	97	10	103	9.0e-14	68.5	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
645476588	444	69.59	56	443	2	387	0.0e+00	678	COG0192	S-adenosylmethionine synthetase	388
645476589	389	44.96	44	389	2	337	5.0e-96	344	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
645476590	73	67.19	1	64	1	64	1.0e-23	101	COG2991	Uncharacterized protein	77
645476593	737	52.26	10	737	1	701	0.0e+00	841	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
645476594	226	55.56	14	226	1	215	2.0e-82	298	COG2999	Glutaredoxin 2	215
645476597	468	41.87	1	455	28	482	6.0e-113	401	COG0513	Superfamily II DNA and RNA helicase	513
645476598	704	53.41	28	695	10	675	0.0e+00	854	COG1200	RecG-like helicase	677
645476600	325	45.34	3	321	2	321	1.0e-78	286	COG3943	Uncharacterized conserved protein	329
645476602	756	60.67	1	756	8	778	0.0e+00	975	COG2183	Transcriptional accessory protein Tex/SPT6	780
645476606	295	41.12	1	295	2	300	5.0e-87	314	COG2264	Ribosomal protein L11 methylase PrmA	300
645476607	453	65.11	1	448	1	449	0.0e+00	631	COG0439	Biotin carboxylase	449
645476609	153	50.68	6	153	1	139	3.0e-26	110	COG0511	Biotin carboxyl carrier protein	140
645476612	343	61.21	1	343	1	347	0.0e+00	503	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
645476617	256	44.83	1	256	1	261	6.0e-90	324	COG0708	Exonuclease III	261
645476618	241	45.37	11	237	1	220	2.0e-73	269	COG2360	Leu/Phe-tRNA-protein transferase	221
645476619	203	46.53	60	203	3	145	2.0e-39	155	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
645476620	127	33.83	1	125	3	135	3.0e-26	110	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
645476621	269	53.93	2	266	1	266	6.0e-91	327	COG0289	Dihydrodipicolinate reductase	266
645476622	316	41.46	1	316	1	312	2.0e-65	242	COG0385	Predicted Na+-dependent transporter	319
645476626	3862	21.52	3146	3862	1	715	1.0e-05	48.2	COG5295	Autotransporter adhesin	715
645476632	239	57.87	8	238	10	241	2.0e-86	312	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
645476634	396	49.71	6	344	3	338	2.0e-89	323	COG0206	Cell division GTPase FtsZ	338
645476635	414	50.84	1	414	1	418	0.0e+00	460	COG0849	Cell division ATPase FtsA	418
645476636	241	33.77	10	232	32	259	7.0e-39	154	COG1589	Cell division septal protein FtsQ	269
645476637	304	43.22	3	301	1	316	3.0e-81	295	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
645476638	469	52.44	1	468	2	459	0.0e+00	576	COG0773	UDP-N-acetylmuramate-alanine ligase	459
645476641	259	26.07	2	232	19	274	2.0e-34	139	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
645476642	355	47.06	4	353	1	354	1.0e-95	343	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
645476643	423	35.56	10	422	2	381	3.0e-78	285	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
645476646	498	32.74	5	495	3	473	3.0e-90	326	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
645476648	445	45.29	3	445	5	446	0.0e+00	472	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
645476655	271	32.96	9	269	2	263	1.0e-49	190	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
645476656	702	38.7	1	702	18	719	0.0e+00	661	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
645476659	497	43.8	89	494	1	377	1.0e-123	436	COG1454	Alcohol dehydrogenase, class IV	377
645476664	182	49.37	1	158	4	160	1.0e-45	176	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
645476665	182	49.46	1	182	11	194	2.0e-61	228	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
645476666	155	44.78	7	139	2	135	6.0e-39	153	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
645476672	140	35.37	1	140	3	127	3.0e-24	104	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
645476673	123	53.66	1	123	1	121	7.0e-30	122	COG3759	Uncharacterized membrane protein	121
645476674	212	34.88	11	212	2	212	2.0e-44	172	COG0602	Organic radical activating enzyme	212
645476678	176	34.46	5	174	10	181	9.0e-24	103	COG3196	Uncharacterized protein CbrC, UPF0167 family	183
645476680	721	31.87	11	721	19	719	4.0e-122	432	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
645476685	867	39.93	1	861	7	859	0.0e+00	669	COG0308	Aminopeptidase N	859
645476687	367	58.52	9	356	5	352	0.0e+00	477	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
645476688	557	36.58	13	557	1	528	0.0e+00	477	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
645476689	326	51.8	1	326	10	343	1.0e-103	369	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
645476691	421	58.25	10	421	1	411	0.0e+00	554	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
645476693	794	50.76	4	789	3	735	0.0e+00	770	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
645476695	273	49.28	4	273	3	272	4.0e-89	321	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
645476696	706	65.71	1	696	1	692	0.0e+00	1003	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
645476700	253	52.63	1	241	1	247	2.0e-87	315	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
645476705	123	54.05	2	111	1	111	4.0e-34	136	COG0360	Ribosomal protein S6	112
645476706	98	34	1	98	3	102	6.0e-25	105	COG2965	Primosomal replication protein N	103
645476707	76	67.16	3	69	9	75	3.0e-19	86.8	COG0238	Ribosomal protein S18	75
645476708	150	58.39	1	149	1	148	6.0e-41	159	COG0359	Ribosomal protein L9	148
645476710	360	39.24	41	355	25	335	7.0e-82	297	COG2951	Membrane-bound lytic murein transglycosylase B	343
645476714	598	28.83	1	383	130	509	2.0e-64	240	COG2812	DNA polymerase III, gamma/tau subunits	515
645476715	111	50.94	1	106	1	104	8.0e-24	102	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
645476719	347	51.9	3	344	12	344	1.0e-122	433	COG1613	ABC-type sulfate transport system, periplasmic component	348
645476721	69	45.59	1	68	1	68	7.0e-14	68.9	COG2608	Copper chaperone CopZ	71
645476724	190	25	4	177	4	167	2.0e-19	89.2	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
645476726	304	32.35	7	304	18	261	1.0e-47	183	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
645476729	471	58.85	215	455	4	244	4.0e-86	312	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
645476731	377	52.17	18	362	14	355	2.0e-111	395	COG2262	50S ribosomal subunit-associated GTPase HflX	411
645476736	784	40.98	56	784	2	712	0.0e+00	658	COG2217	Cation transport ATPase	713
645476741	664	42.37	1	663	1	638	0.0e+00	653	COG0323	DNA mismatch repair ATPase MutL	638
645476744	445	58.13	84	286	2	203	5.0e-85	308	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
645476751	1298	36.04	162	992	1	743	0.0e+00	742	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
645476753	260	22.94	54	253	79	302	5.0e-22	98.1	COG0501	Zn-dependent protease with chaperone function	302
645476757	422	67.65	9	416	1	402	0.0e+00	668	COG1219	ATP-dependent protease Clp, ATPase subunit	408
645476758	861	79.17	1	861	1	852	0.0e+00	1505	COG1049	Aconitase B	852
645476759	356	32.14	1	356	1	364	1.0e-55	210	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
645476760	371	31.59	1	353	2	364	7.0e-51	194	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
645476762	469	44.78	16	467	25	482	0.0e+00	480	COG0260	Leucyl aminopeptidase	485
645476765	762	17.65	1	762	21	768	3.0e-37	150	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
645476767	418	28.9	1	417	5	382	1.0e-52	200	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
645476768	440	51.47	1	436	20	450	0.0e+00	476	COG1115	Na+/alanine symporter	452
645476773	208	56.5	2	198	1	200	6.0e-76	277	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
645476774	212	41.97	2	193	17	204	6.0e-42	164	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
645476776	146	32.88	1	145	1	144	6.0e-30	123	COG2927	DNA polymerase III, chi subunit	144
645476779	219	48.08	16	218	2	200	3.0e-64	238	COG3738	Uncharacterized protein YijF, DUF1287 family	200
645476780	300	32.28	21	300	19	296	6.0e-44	171	COG0501	Zn-dependent protease with chaperone function	302
645476782	216	36.02	1	211	22	227	3.0e-42	165	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
645476783	102	45.92	3	100	1	98	1.0e-16	78.4	COG4541	Uncharacterized membrane protein	100
645476784	249	48.56	2	243	19	257	1.0e-70	259	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
645476785	317	45.69	6	316	1	311	1.0e-94	339	COG0039	Malate/lactate dehydrogenase	313
645476788	637	19.84	268	614	110	463	2.0e-24	107	COG0286	Type I restriction-modification system, DNA methylase subunit	489
645476789	262	39.55	1	262	5	267	2.0e-66	245	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
645476790	308	26.5	1	306	12	308	2.0e-30	127	COG2017	Galactose mutarotase or related enzyme	308
645476791	538	27.79	136	522	2	399	4.0e-33	136	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
645476794	210	56.4	2	210	4	214	1.0e-79	289	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
645476795	181	54.05	34	180	2	147	2.0e-50	191	COG0756	dUTPase	148
645476796	312	34.64	8	310	3	305	2.0e-56	213	COG4261	Predicted acyltransferase, LPLAT superfamily	309
645476797	241	20.24	1	240	3	235	1.0e-10	60.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
645476804	179	44.02	6	179	10	193	6.0e-35	140	COG4648	Uncharacterized membrane protein	201
645476806	83	25	1	80	1	80	4.0e-07	46.5	COG0236	Acyl carrier protein	80
645476807	86	30.23	1	86	3	80	1.0e-05	41.8	COG0236	Acyl carrier protein	80
645476808	259	26.47	29	257	2	235	4.0e-19	88.8	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
645476810	141	34.78	1	135	22	152	2.0e-23	101	COG4706	Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain	161
645476811	242	41.43	1	241	4	250	1.0e-41	163	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
645476812	414	40.72	3	409	1	411	1.0e-112	400	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
645476813	56	60.38	1	53	1	53	1.0e-14	71.4	COG1773	Rubredoxin	55
645476814	362	21.6	4	358	10	384	1.0e-27	117	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
645476815	196	31.64	19	190	1	177	4.0e-21	94.5	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
645476817	312	58.03	3	306	1	305	2.0e-108	385	COG0181	Porphobilinogen deaminase	307
645476820	171	42.76	19	169	5	153	2.0e-37	148	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
645476821	274	59.42	1	274	9	283	4.0e-104	371	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
645476822	834	45.12	30	726	1	705	0.0e+00	711	COG0557	Exoribonuclease R	706
645476829	241	32.52	2	239	18	258	5.0e-37	148	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
645476859	668	26.28	4	652	1	608	8.0e-72	265	COG5525	Phage terminase, large subunit GpA	611
645476863	520	27.27	30	518	16	487	6.0e-77	281	COG5511	Bacteriophage capsid protein	492
645476873	110	36.36	1	110	2	111	1.0e-21	94.6	COG4718	Phage-related protein	111
645476874	240	53.51	13	240	8	231	1.0e-76	279	COG4672	Phage-related protein	231
645476875	251	34.85	5	127	2	133	4.0e-15	75.2	COG1310	Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif	134
645476876	240	41.45	1	183	5	195	7.0e-36	144	COG4723	Phage-related protein, tail component	198
645476877	1714	30.58	3	927	2	927	0.0e+00	622	COG4733	Phage-related protein, tail component	952
645476886	323	31.79	1	173	6	172	4.0e-31	128	COG3617	Prophage antirepressor	176
645476893	390	44.32	11	380	1	348	2.0e-113	402	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
645476895	148	37.5	1	143	1	144	2.0e-37	148	COG1959	DNA-binding transcriptional regulator, IscR family	150
645476900	128	50.34	1	128	5	148	7.0e-37	145	COG0822	NifU homolog involved in Fe-S cluster formation	150
645476903	106	57.94	1	106	4	110	8.0e-39	151	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
645476904	168	34.94	2	165	1	166	5.0e-22	97.3	COG1076	DnaJ-domain-containing proteins 1	174
645476905	359	40.06	20	358	1	334	8.0e-77	280	COG0859	ADP-heptose:LPS heptosyltransferase	334
645476907	136	40.74	1	133	18	138	1.0e-24	105	COG0394	Protein-tyrosine-phosphatase	139
645476910	286	57.92	10	249	1	240	7.0e-99	353	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
645476911	287	29.54	1	271	1	275	4.0e-23	102	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
645476912	424	29.69	1	424	5	438	6.0e-56	212	COG4097	Predicted ferric reductase	438
645476915	313	31.99	1	313	2	323	5.0e-36	145	COG1275	Tellurite resistance protein TehA and related permeases	329
645476919	509	40.66	201	501	1	300	2.0e-83	303	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
645476920	572	43.93	1	572	1	577	0.0e+00	598	COG0018	Arginyl-tRNA synthetase	577
645476922	226	37.1	5	65	4	64	6.0e-06	44.7	COG1278	Cold shock protein, CspA family	67
645476923	245	29.79	49	232	43	230	1.0e-28	120	COG2849	Antitoxin component YwqK of the YwqJK toxin-antitoxin module	230
645476925	299	40.34	10	297	1	278	1.0e-56	213	COG2890	Methylase of polypeptide chain release factors	280
645476926	371	60.87	4	371	1	367	0.0e+00	547	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
645476931	134	69.4	1	134	42	175	7.0e-51	192	COG0290	Translation initiation factor IF-3	176
645476932	97	61.54	33	97	1	65	7.0e-17	78.7	COG0291	Ribosomal protein L35	65
645476933	119	80.51	1	118	1	118	1.0e-39	154	COG0292	Ribosomal protein L20	118
645476935	329	54.49	1	327	3	335	7.0e-127	446	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
645476936	139	37.93	1	115	2	115	1.0e-22	98.9	COG3727	G:T-mismatch repair DNA endonuclease, very short patch repair protein	150
645476937	357	36.14	47	357	1	324	2.0e-65	242	COG0270	Site-specific DNA-cytosine methylase	328
645476939	787	42.57	144	786	1	650	0.0e+00	653	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
645476940	100	44.68	2	95	1	93	5.0e-26	109	COG0776	Bacterial nucleoid DNA-binding protein	94
645476947	478	48.71	15	478	9	471	0.0e+00	501	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
645476951	590	40.13	1	590	1	565	0.0e+00	484	COG0358	DNA primase (bacterial type)	568
645476953	649	49.27	303	643	3	342	2.0e-91	330	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
645476955	304	40.13	1	301	2	271	3.0e-71	262	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
645476956	123	47.37	9	120	5	118	2.0e-29	121	COG0858	Ribosome-binding factor A	118
645476957	346	30.62	1	346	1	340	8.0e-46	177	COG0673	Predicted dehydrogenase	342
645476959	208	59.81	1	208	2	210	5.0e-81	293	COG0035	Uracil phosphoribosyltransferase	210
645476961	111	64.76	7	111	1	105	8.0e-32	128	COG4390	Uncharacterized protein	106
645476963	268	50.56	1	264	1	264	5.0e-83	301	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
645476967	164	48.28	20	163	6	147	9.0e-33	133	COG3909	Cytochrome c556	147
645476968	287	53.97	15	252	9	246	2.0e-83	302	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
645476969	158	22.44	3	158	2	141	5.0e-22	97.3	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
645476970	309	32.81	7	309	1	315	5.0e-62	231	COG0523	GTPase, G3E family	323
645476974	350	57.02	1	349	1	363	0.0e+00	484	COG4174	ABC-type microcin C transport system, permease component YejB	364
645476975	348	54.88	18	345	12	338	1.0e-115	410	COG4239	ABC-type microcin C transport system, permease component YejE	341
645476977	513	37.86	1	513	5	527	3.0e-125	442	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
645476979	515	52.75	1	511	2	528	0.0e+00	642	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
645476981	419	39.4	120	418	53	354	5.0e-77	281	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
645476982	283	59.17	2	283	1	289	8.0e-78	283	COG3782	Uncharacterized protein	289
645476984	126	44.54	1	119	10	126	5.0e-26	110	COG4273	Uncharacterized protein, contains metal-binding DGC domain	135
645476986	1145	23.18	153	1145	41	929	4.0e-65	244	COG5373	Uncharacterized membrane protein	931
645476991	431	58.53	1	429	1	426	0.0e+00	583	COG0172	Seryl-tRNA synthetase	429
645476992	188	40.31	3	188	2	181	2.0e-59	222	COG0717	Deoxycytidine triphosphate deaminase	183
645476993	138	37.32	1	138	1	139	1.0e-29	121	COG4642	Uncharacterized conserved protein	139
645476994	299	44.19	1	299	1	301	4.0e-107	381	COG2974	DNA recombination-dependent growth factor C	303
645477003	232	31.63	46	231	68	262	6.0e-23	101	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
645477005	102	57.69	1	102	23	125	6.0e-22	95.8	COG3308	Uncharacterized membrane protein	131
645477006	610	19.81	23	435	24	421	1.0e-17	85.6	COG3307	O-antigen ligase	424
645477007	410	16.33	3	397	1	386	7.0e-12	65.2	COG2814	Predicted arabinose efflux permease, MFS family	394
645477008	280	40	1	262	1	266	7.0e-38	150	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
645477013	389	45.8	1	389	2	394	5.0e-128	451	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
645477017	372	52.35	1	360	111	445	7.0e-120	423	COG0166	Glucose-6-phosphate isomerase	446
645477023	333	55.06	15	329	5	320	9.0e-124	436	COG0837	Glucokinase	320
645477024	231	32.46	4	227	3	228	7.0e-47	180	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
645477025	481	51.43	1	480	2	483	0.0e+00	647	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
645477027	611	40.89	13	610	5	575	0.0e+00	637	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
645477029	212	58.49	1	211	1	211	3.0e-66	244	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
645477030	436	51.52	7	431	5	418	0.0e+00	538	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
645477032	544	65.38	2	543	1	531	0.0e+00	899	COG0504	CTP synthase (UTP-ammonia lyase)	533
645477033	305	38.7	4	287	20	304	9.0e-60	223	COG1560	Lauroyl/myristoyl acyltransferase	308
645477034	146	44.27	1	131	1	130	1.0e-34	138	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
645477036	587	45.41	2	575	1	538	0.0e+00	528	COG3975	Predicted metalloprotease, contains C-terminal PDZ domain	558
645477037	481	74.42	9	479	10	481	0.0e+00	702	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
645477038	203	61.43	2	203	1	223	8.0e-91	326	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
645477039	56	25	1	56	5	60	2.0e-07	47.1	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
645477040	454	48.84	324	451	3	126	5.0e-31	129	COG3245	Cytochrome c5	126
645477041	184	39.88	14	181	9	159	1.0e-40	159	COG3236	Predicted NAD-dependent protein-ADP-ribosyltransferase YbiA, DUF1768 family	162
645477042	432	48.73	1	432	2	401	0.0e+00	469	COG0162	Tyrosyl-tRNA synthetase	401
645477045	363	66.67	1	363	1	372	0.0e+00	530	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
645477048	503	50.3	1	502	7	511	0.0e+00	527	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
645477049	687	53.54	1	686	1	690	0.0e+00	833	COG0751	Glycyl-tRNA synthetase, beta subunit	691
645477054	221	47.93	10	221	10	224	3.0e-41	161	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
645477055	121	66.38	1	116	3	115	7.0e-39	152	COG0335	Ribosomal protein L19	115
645477056	249	57.68	1	240	1	239	9.0e-101	359	COG0336	tRNA G37 N-methylase TrmD	240
645477057	169	40.12	1	169	1	172	9.0e-44	169	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
645477058	82	58.54	1	82	1	81	9.0e-26	108	COG0228	Ribosomal protein S16	87
645477059	625	14.88	1	447	173	598	8.0e-22	99.3	COG1042	Acyl-CoA synthetase (NDP forming)	598
645477062	471	28.66	140	457	21	330	3.0e-40	159	COG0642	Signal transduction histidine kinase	336
645477063	225	43.67	3	225	2	228	4.0e-59	221	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
645477066	362	52.17	89	362	2	277	7.0e-96	344	COG0077	Prephenate dehydratase	279
645477069	155	21.09	1	138	1	147	7.0e-08	50.1	COG4276	Ligand-binding SRPBCC domain	153
645477070	157	31.97	5	149	1	139	3.0e-21	94.7	COG4968	Tfp pilus assembly protein PilE	139
645477072	393	27.32	1	370	2	352	8.0e-31	128	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
645477073	645	53.1	3	226	1	226	6.0e-80	292	COG1136	ABC-type lipoprotein export system, ATPase component	226
645477074	233	25.89	10	229	1	210	2.0e-25	109	COG0625	Glutathione S-transferase	211
645477080	460	28.12	16	455	1	444	3.0e-51	196	COG1538	Outer membrane protein TolC	457
645477084	136	45.11	1	128	4	136	1.0e-43	168	COG2969	Stringent starvation protein B	155
645477086	548	46.1	246	545	6	305	6.0e-77	282	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
645477087	73	60.27	1	73	2	74	8.0e-26	108	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
645477088	112	42.06	5	111	1	107	1.0e-18	84.9	COG0594	RNase P protein component	117
645477091	516	50.99	160	512	60	408	3.0e-117	415	COG0593	Chromosomal replication initiation ATPase DnaA	408
645477092	367	40.61	7	367	6	364	2.0e-89	323	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
645477093	161	27.74	10	161	18	167	2.0e-13	68.9	COG1495	Disulfide bond formation protein DsbB	170
645477095	553	33.26	9	467	1	396	6.0e-78	285	COG0644	Dehydrogenase (flavoprotein)	396
645477100	368	51.49	1	368	1	365	0.0e+00	480	COG1932	Phosphoserine aminotransferase	365
645477101	189	47.37	41	187	2	153	2.0e-43	168	COG0779	Ribosome maturation factor RimP	153
645477102	500	54.55	163	359	1	190	4.0e-46	179	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
645477103	972	62.38	472	972	3	507	0.0e+00	668	COG0532	Translation initiation factor IF-2, a GTPase	509
645477115	751	58.34	3	751	1	714	0.0e+00	855	COG3256	Nitric oxide reductase large subunit	717
645477116	402	23.1	8	372	10	426	3.0e-26	112	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
645477118	256	28.23	1	254	31	310	2.0e-36	146	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
645477120	372	35.65	5	338	3	341	2.0e-75	275	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
645477122	392	28.1	77	389	51	381	3.0e-31	129	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
645477128	333	35.76	14	328	14	327	5.0e-55	208	COG1466	DNA polymerase III, delta subunit	334
645477129	159	37.74	1	158	4	162	6.0e-33	133	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
645477130	324	26.33	28	322	6	282	1.0e-17	84	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
645477133	397	62.12	2	397	1	396	0.0e+00	630	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
645477134	136	35.92	5	136	17	157	3.0e-17	80.7	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
645477135	407	53.51	1	405	3	412	2.0e-107	383	COG0738	Fucose permease	422
645477137	462	33.63	13	462	22	472	1.0e-72	267	COG1757	Na+/H+ antiporter NhaC	485
645477138	210	56.73	1	208	1	208	9.0e-88	316	COG0177	Endonuclease III	211
645477140	517	47.47	122	416	52	346	2.0e-71	263	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
645477141	506	35.41	6	499	1	485	5.0e-78	285	COG1757	Na+/H+ antiporter NhaC	485
645477142	350	44.52	1	306	9	308	4.0e-76	278	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
645477149	264	77.07	1	264	3	268	1.0e-128	452	COG0207	Thymidylate synthase	268
645477151	198	29.29	1	198	47	231	4.0e-17	81.2	COG2801	Transposase InsO and inactivated derivatives	232
645477152	367	67.36	130	367	1	239	8.0e-100	357	COG1186	Protein chain release factor B	239
645477157	482	28	118	459	107	425	9.0e-38	151	COG2425	Uncharacterized protein, contains a von Willebrand factor type A (vWA) domain	437
645477158	535	23.57	17	304	3	297	4.0e-36	146	COG0714	MoxR-like ATPase	329
645477160	938	40.52	23	723	11	707	0.0e+00	618	COG1643	HrpA-like RNA helicase	845
645477167	259	42.21	2	255	1	260	1.0e-79	289	COG0708	Exonuclease III	261
645477170	334	46.15	43	334	3	289	1.0e-85	310	COG0167	Dihydroorotate dehydrogenase	310
645477175	1934	25.96	1	554	8	540	2.0e-73	272	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
645477183	264	21.85	33	264	12	244	2.0e-23	102	COG1651	Protein-disulfide isomerase	244
645477185	559	50.62	5	558	170	729	0.0e+00	681	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
645477189	243	33.73	1	242	1	244	5.0e-30	124	COG3279	DNA-binding response regulator, LytR/AlgR family	244
645477190	176	43.31	6	162	2	154	2.0e-48	185	COG0669	Phosphopantetheine adenylyltransferase	159
645477194	325	22.77	1	318	2	313	2.0e-20	93	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
645477195	556	17.82	3	313	5	332	5.0e-08	53.1	COG1106	ATPase/GTPase, AAA15 family	371
645477196	265	25.81	21	265	9	255	3.0e-29	122	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
645477197	231	37.07	1	217	2	232	8.0e-40	157	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
645477198	204	64.22	1	204	1	204	4.0e-58	217	COG4300	Cadmium resistance protein CadD, predicted permease	205
645477199	365	36.39	5	364	16	396	2.0e-67	249	COG3213	Uncharacterized protein involved in response to NO	396
645477200	762	53.56	75	759	1	685	0.0e+00	949	COG0855	Polyphosphate kinase	696
645477202	324	57.05	4	322	2	319	1.0e-96	346	COG4606	ABC-type enterochelin transport system, permease component	321
645477204	307	48.44	83	307	91	315	1.0e-71	263	COG4605	ABC-type enterochelin transport system, permease component	316
645477209	267	56.18	16	266	1	251	9.0e-111	393	COG4604	ABC-type enterochelin transport system, ATPase component	252
645477211	112	50.93	5	112	3	110	4.0e-37	146	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
645477212	228	30.77	10	228	1	213	2.0e-37	149	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
645477215	347	50	3	347	1	349	7.0e-127	446	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
645477216	281	61.74	17	280	2	263	1.0e-94	339	COG3739	Uncharacterized membrane protein YoaT, DUF817 family	263
645477219	463	33.18	38	462	1	445	6.0e-79	288	COG0415	Deoxyribodipyrimidine photolyase	461
645477221	98	44.71	12	96	11	95	5.0e-14	69.2	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
645477223	1091	18.95	6	1088	12	1188	1.0e-53	205	COG3523	Type VI protein secretion system component VasK	1188
645477225	588	34.36	1	579	1	612	2.0e-129	456	COG3519	Type VI protein secretion system component VasA	621
645477226	350	31.62	58	339	17	303	7.0e-45	174	COG3520	Predicted component of the type VI protein secretion system	335
645477227	161	27.27	2	132	3	132	3.0e-14	71.5	COG3521	Predicted component of the type VI protein secretion system	159
645477232	149	62	2	149	3	148	1.0e-31	128	COG3399	Uncharacterized protein	148
645477234	334	25.44	48	326	26	296	1.0e-22	100	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
645477239	245	52.34	14	245	1	234	8.0e-73	266	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
645477240	657	18.37	5	657	12	699	5.0e-28	119	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
645477241	277	52.22	71	273	6	208	2.0e-56	212	COG0560	Phosphoserine phosphatase	212
645477242	513	63.29	2	366	1	356	1.0e-124	440	COG3288	NAD/NADP transhydrogenase alpha subunit	356
645477243	127	59.06	1	127	1	124	3.0e-32	130	COG3686	Uncharacterized conserved protein, MAPEG superfamily	125
645477244	138	37.12	4	131	2	132	5.0e-18	83.5	COG3791	Uncharacterized conserved protein	133
645477246	461	57.47	1	459	1	463	0.0e+00	629	COG1282	NAD/NADP transhydrogenase beta subunit	463
645477250	651	49.81	1	533	22	537	0.0e+00	558	COG1292	Choline-glycine betaine transporter	537
645477252	309	27.7	32	305	22	285	2.0e-41	163	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
645477253	417	44.47	28	412	3	389	2.0e-98	352	COG1686	D-alanyl-D-alanine carboxypeptidase	389
645477254	526	53.18	23	364	3	347	1.0e-121	430	COG1171	Threonine dehydratase	347
645477257	241	56.6	7	240	11	230	5.0e-73	267	COG0689	Ribonuclease PH	230
645477260	478	37.67	6	430	5	424	2.0e-77	283	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
645477261	358	32.41	1	358	1	337	2.0e-76	279	COG2845	Uncharacterized protein	354
645477263	344	52.06	1	340	1	338	2.0e-116	412	COG0547	Anthranilate phosphoribosyltransferase	338
645477264	196	64.71	1	186	3	189	1.0e-83	302	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
645477269	476	53.62	35	476	1	436	0.0e+00	544	COG2704	Anaerobic C4-dicarboxylate transporter	436
645477271	162	40.76	1	155	1	156	4.0e-16	77.9	COG2839	Uncharacterized conserved protein YqgC, DUF456 family	160
645477272	219	35.87	3	217	1	214	2.0e-40	159	COG3318	Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C motif	216
645477274	263	31.32	7	261	1	257	4.0e-54	204	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
645477277	199	34.76	7	193	2	181	2.0e-31	129	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
645477278	399	27.76	1	253	37	298	5.0e-33	135	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
645477279	319	64.67	2	318	1	317	0.0e+00	508	COG0825	Acetyl-CoA carboxylase alpha subunit	317
645477281	133	53.19	4	97	3	96	5.0e-25	106	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
645477282	336	41.93	1	314	3	314	5.0e-91	327	COG0180	Tryptophanyl-tRNA synthetase	314
645477286	620	46.73	18	606	4	579	0.0e+00	546	COG0443	Molecular chaperone DnaK (HSP70)	579
645477288	252	40.12	1	158	2	151	5.0e-45	174	COG3779	Uncharacterized conserved protein YegJ, DUF2314 family	151
645477294	113	44.86	1	105	1	102	4.0e-18	83.2	COG0633	Ferredoxin	102
645477297	65	64.62	1	65	1	64	8.0e-20	88.5	COG2975	Fe-S-cluster formation regulator IscX/YfhJ	64
645477299	339	46.76	54	339	1	291	1.0e-84	306	COG0685	5,10-methylenetetrahydrofolate reductase	291
645477300	758	60.24	424	755	1	330	1.0e-125	444	COG0620	Methionine synthase II (cobalamin-independent)	330
645477301	199	21.31	4	186	2	176	4.0e-10	58.3	COG1704	Uncharacterized conserved protein	185
645477303	198	27.09	1	194	1	202	8.0e-19	86.9	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
645477307	640	43.42	1	522	3	530	0.0e+00	546	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
645477308	255	61.54	1	247	2	240	1.0e-106	379	COG1126	ABC-type polar amino acid transport system, ATPase component	240
645477309	227	46.36	6	224	7	221	1.0e-56	213	COG0765	ABC-type amino acid transport system, permease component	222
645477310	316	36.4	67	316	11	270	9.0e-37	147	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
645477313	186	47.29	1	128	3	129	1.0e-32	132	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
645477319	299	37.67	8	292	3	284	6.0e-58	217	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
645477321	174	49.71	1	173	1	172	4.0e-45	174	COG3658	Cytochrome b	192
645477323	465	71.55	1	464	2	464	0.0e+00	776	COG1027	Aspartate ammonia-lyase	471
645477327	160	40.56	10	151	2	144	1.0e-37	149	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
645477329	127	38.89	8	127	4	129	9.0e-30	122	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
645477330	348	62.46	1	282	3	279	3.0e-92	332	COG0468	RecA/RadA recombinase	279
645477331	103	63.11	1	103	1	103	9.0e-46	174	COG0278	Glutaredoxin-related protein	105
645477333	90	60	1	90	1	90	5.0e-26	109	COG3830	ACT domain, binds amino acids and other small ligands	90
645477334	451	71.94	3	451	1	445	0.0e+00	601	COG2848	Uncharacterized conserved protein, UPF0210 family	445
645477338	239	47.46	4	234	1	235	1.0e-62	233	COG0571	dsRNA-specific ribonuclease	235
645477340	121	78.22	15	115	1	101	6.0e-37	145	COG4859	Uncharacterized protein	105
645477341	159	44.97	1	145	1	149	8.0e-44	169	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
645477342	143	41.1	1	139	6	151	2.0e-32	131	COG0781	Transcription termination factor NusB	151
645477347	693	45.51	32	684	1	574	0.0e+00	599	COG1966	Carbon starvation protein CstA	575
645477348	64	47.69	1	64	1	65	2.0e-19	87.7	COG2879	Uncharacterized short protein YbdD, DUF466 family	65
645477352	148	31.03	34	148	1	116	1.0e-09	55.8	COG3335	Transposase	132
645477359	126	37.01	1	126	10	135	5.0e-26	109	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
645477365	760	21.44	223	751	188	724	2.0e-50	194	COG1203	CRISPR/Cas system-associated endonuclease/helicase Cas3	733
645477370	288	31.8	1	254	1	246	1.0e-38	153	COG3649	CRISPR/Cas system type I-B associated protein Csh2, Cas7 group, RAMP superfamily	283
645477371	217	25.14	17	199	15	190	1.0e-24	107	COG1468	CRISPR/Cas system-associated exonuclease Cas4, RecB family	190
645477372	285	29.96	1	262	9	275	2.0e-33	136	COG0863	DNA modification methylase	302
645477374	337	36.53	6	336	4	327	5.0e-64	238	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
645477375	97	36.56	1	93	1	89	2.0e-16	77.2	COG1343	CRISPR/Cas system-associated endoribonuclease Cas2	89
645477389	450	35.32	13	449	5	442	9.0e-57	214	COG0038	H+/Cl- antiporter ClcA	443
645477393	305	37.12	6	304	2	297	2.0e-66	245	COG2177	Cell division protein FtsX	297
645477394	229	52.31	14	229	1	216	2.0e-87	315	COG2884	ABC-type ATPase involved in cell division	223
645477398	534	38.98	7	534	6	457	6.0e-126	444	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
645477399	255	24.43	4	255	82	333	2.0e-26	112	COG0642	Signal transduction histidine kinase	336
645477401	769	42.26	18	769	13	752	0.0e+00	723	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
645477402	509	32.89	6	509	10	534	4.0e-62	232	COG1178	ABC-type Fe3+ transport system, permease component	540
645477409	380	29.24	117	374	2	275	8.0e-35	141	COG4253	Uncharacterized conserved protein, DUF2345 family	278
645477416	310	26.23	11	305	9	306	3.0e-14	72.6	COG0679	Predicted permease	311
645477418	437	57.83	6	436	3	436	2.0e-120	426	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
645477422	269	42.75	4	269	2	266	2.0e-42	166	COG0428	Zinc transporter ZupT	266
645477424	568	39.86	5	542	8	546	8.0e-118	417	COG0443	Molecular chaperone DnaK (HSP70)	579
645477427	194	52.74	1	193	1	201	2.0e-58	218	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
645477428	423	53.62	31	421	1	393	0.0e+00	487	COG0126	3-phosphoglycerate kinase	395
645477429	550	21.74	10	459	1	443	5.0e-24	106	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
645477431	327	18.98	2	310	1	330	2.0e-12	66.5	COG3203	Outer membrane protein (porin)	354
645477432	525	33.71	2	514	21	553	3.0e-97	349	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
645477433	598	29.76	161	551	2	381	3.0e-59	223	COG0006	Xaa-Pro aminopeptidase	384
645477435	306	42.72	1	306	1	315	1.0e-82	300	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
645477436	302	46.34	17	302	2	287	2.0e-72	265	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
645477437	534	56.55	1	534	2	533	0.0e+00	725	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
645477456	306	54.6	1	305	1	314	3.0e-116	411	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
645477457	152	53.59	1	152	2	153	7.0e-52	196	COG1781	Aspartate carbamoyltransferase, regulatory subunit	153
645477460	334	47.67	1	332	12	351	9.0e-104	370	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
645477461	793	30.29	80	793	47	781	7.0e-125	442	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
645477462	331	22.95	36	321	8	295	2.0e-13	70.5	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
645477468	404	22.01	38	403	38	390	7.0e-12	65.6	COG2814	Predicted arabinose efflux permease, MFS family	394
645477470	425	41.01	3	414	2	416	8.0e-121	427	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
645477471	448	61.83	19	444	6	432	0.0e+00	596	COG0001	Glutamate-1-semialdehyde aminotransferase	432
645477474	496	50.93	123	495	66	437	0.0e+00	466	COG0621	tRNA A37 methylthiotransferase MiaB	437
645477475	374	53.64	4	373	1	369	1.0e-122	433	COG0263	Glutamate 5-kinase	369
645477478	258	53.49	1	258	3	260	1.0e-105	376	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
645477479	182	52.78	37	178	1	142	7.0e-42	163	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
645477480	347	53.12	3	337	1	335	5.0e-101	361	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
645477481	180	38.41	23	180	7	170	4.0e-20	91.2	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
645477482	799	41.57	1	799	1	766	0.0e+00	705	COG4775	Outer membrane protein assembly factor BamA	766
645477485	394	58.42	3	393	1	383	0.0e+00	544	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
645477487	264	31.25	1	254	1	254	9.0e-38	150	COG0575	CDP-diglyceride synthetase	265
645477488	248	52.17	14	237	16	245	9.0e-88	316	COG0020	Undecaprenyl pyrophosphate synthase	245
645477489	185	55.68	1	185	3	187	5.0e-61	227	COG0233	Ribosome recycling factor	187
645477491	317	34.23	1	296	4	287	9.0e-59	220	COG1131	ABC-type multidrug transport system, ATPase component	293
645477493	329	30.61	25	307	2	286	2.0e-52	199	COG0616	Periplasmic serine protease, ClpP class	317
645477500	363	57.61	2	362	1	367	0.0e+00	527	COG0082	Chorismate synthase	369
645477506	256	47.09	54	254	3	207	2.0e-65	242	COG0135	Phosphoribosylanthranilate isomerase	208
645477507	489	43.83	7	489	10	488	0.0e+00	539	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
645477511	346	35.41	1	344	1	349	3.0e-77	282	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
645477514	252	34.72	21	234	11	225	6.0e-44	170	COG3541	Predicted nucleotidyltransferase	248
645477516	430	54.88	1	430	1	423	0.0e+00	561	COG0141	Histidinol dehydrogenase	425
645477517	302	57.34	3	285	1	259	6.0e-70	257	COG3680	Uncharacterized protein	259
645477518	222	50.68	4	218	1	217	6.0e-63	233	COG0040	ATP phosphoribosyltransferase	290
645477520	237	52.17	56	237	23	204	5.0e-47	180	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
645477524	580	50.1	77	576	6	508	0.0e+00	569	COG4262	Predicted spermidine synthase with an N-terminal membrane domain	508
645477525	118	44.44	2	118	16	132	2.0e-21	94.1	COG3766	Uncharacterized membrane protein YjfL, UPF0719 family	133
645477529	336	34.93	4	334	6	340	4.0e-82	298	COG4260	Membrane protease subunit, stomatin/prohibitin family, contains C-terminal Zn-ribbon domain	345
645477534	630	71.29	33	630	5	603	0.0e+00	1067	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
645477535	233	48.29	2	233	1	233	2.0e-58	219	COG0775	Nucleoside phosphorylase	234
645477536	375	66.22	7	375	2	374	0.0e+00	577	COG5008	Tfp pilus assembly protein, ATPase PilU	375
645477537	249	27.35	3	214	16	248	2.0e-16	79.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
645477539	352	50.7	1	350	2	358	8.0e-115	407	COG0787	Alanine racemase	360
645477540	643	61.94	1	606	4	579	0.0e+00	659	COG0443	Molecular chaperone DnaK (HSP70)	579
645477541	190	44.85	4	189	1	193	8.0e-32	130	COG0576	Molecular chaperone GrpE (heat shock protein)	193
645477542	272	56.02	81	270	3	193	6.0e-69	254	COG1045	Serine acetyltransferase	194
645477543	164	59.39	1	164	1	163	1.0e-60	225	COG4314	Nitrous oxide reductase accessory protein NosL	176
645477544	276	26.33	1	276	1	277	2.0e-13	69.8	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
645477548	435	57.18	11	398	18	399	0.0e+00	493	COG3420	Nitrous oxidase accessory protein NosD, contains tandem CASH domains	408
645477549	656	56.48	11	655	10	637	0.0e+00	793	COG4263	Nitrous oxide reductase	637
645477550	768	42.97	3	500	17	481	1.0e-122	434	COG3901	Regulator of nitric oxide reductase transcription	482
645477552	378	41.47	1	378	2	363	7.0e-86	311	COG0687	Spermidine/putrescine-binding periplasmic protein	363
645477554	373	22.51	2	373	3	354	1.0e-30	127	COG3203	Outer membrane protein (porin)	354
645477555	282	52.53	6	158	38	191	1.0e-45	176	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
645477558	383	42.05	4	383	3	388	1.0e-89	323	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
645477564	290	37.06	7	288	1	286	2.0e-69	256	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
645477565	145	44.29	3	142	2	137	7.0e-44	169	COG1607	Acyl-CoA hydrolase	157
645477568	710	22.66	3	232	1	278	7.0e-06	46.3	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
645477571	275	55.96	1	275	1	273	9.0e-102	363	COG0266	Formamidopyrimidine-DNA glycosylase	273
645477572	256	20.65	15	255	8	235	5.0e-20	91.9	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
645477573	245	68.26	3	164	1	165	3.0e-69	255	COG0678	Peroxiredoxin	165
645477576	468	33.77	2	458	1	454	2.0e-97	349	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
645477579	500	56.75	177	497	1	325	1.0e-108	387	COG0280	Phosphotransacetylase	327
645477581	462	67.1	1	462	1	462	0.0e+00	772	COG0114	Fumarate hydratase class II	462
645477582	322	45.83	252	322	6	77	1.0e-20	94.2	COG0425	TusA-related sulfurtransferase	78
645477587	344	66.28	1	343	2	344	0.0e+00	533	COG0418	Dihydroorotase	344
645477589	781	25.66	15	781	22	782	1.0e-60	228	COG4258	Predicted exporter	788
645477592	344	25.91	61	339	80	407	4.0e-23	102	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
645477594	417	25	205	410	81	282	4.0e-14	73	COG0842	ABC-type multidrug transport system, permease component	286
645477595	304	37.33	1	288	4	288	8.0e-67	247	COG1131	ABC-type multidrug transport system, ATPase component	293
645477598	385	21.07	9	382	3	319	4.0e-40	159	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
645477599	81	26.92	1	77	6	83	2.0e-08	50.7	COG2388	Predicted acetyltransferase, GNAT superfamily	99
645477601	196	23.86	1	190	5	194	6.0e-06	44.2	COG2834	Outer membrane lipoprotein-sorting protein	211
645477602	177	33.04	41	154	6	118	2.0e-20	92.2	COG0824	Acyl-CoA thioesterase FadM	137
645477603	670	16.05	50	616	31	587	2.0e-28	121	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
645477606	659	62.75	1	659	6	662	0.0e+00	1051	COG0021	Transketolase	663
645477609	392	38.71	53	392	1	319	4.0e-73	268	COG0348	Polyferredoxin	386
645477611	189	45.79	1	189	25	206	2.0e-52	198	COG1859	RNA:NAD 2'-phosphotransferase, TPT1/KptA family	211
645477612	491	47.7	19	490	1	462	0.0e+00	504	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
645477615	666	45.31	1	638	1	649	0.0e+00	600	COG0210	Superfamily I DNA or RNA helicase	655
645477617	278	53.31	4	275	3	274	3.0e-70	258	COG0555	ABC-type sulfate transport system, permease component	274
645477619	286	66.55	1	284	4	287	2.0e-109	388	COG4208	ABC-type sulfate transport system, permease component	287
645477620	357	51.55	1	350	1	345	3.0e-118	418	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
645477624	314	31.36	1	307	1	351	6.0e-51	194	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
645477626	404	40.57	4	398	16	434	7.0e-79	287	COG2233	Xanthine/uracil permease	451
645477628	219	52.51	3	219	2	220	4.0e-69	254	COG0283	Cytidylate kinase	222
645477629	561	59.16	2	546	1	537	0.0e+00	594	COG0539	Ribosomal protein S1	541
645477630	104	47.92	1	96	2	91	2.0e-25	107	COG0776	Bacterial nucleoid DNA-binding protein	94
645477632	378	47.91	16	374	9	367	0.0e+00	460	COG1485	Predicted ATPase	367
645477633	141	62.96	2	136	1	135	5.0e-56	209	COG0105	Nucleoside diphosphate kinase	135
645477635	364	57.39	2	351	1	349	0.0e+00	470	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
645477636	251	44.03	9	251	10	250	3.0e-64	238	COG3063	Tfp pilus assembly protein PilF	250
645477638	421	45.43	5	409	2	361	8.0e-129	453	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
645477640	198	27.78	1	198	47	231	1.0e-17	82.7	COG2801	Transposase InsO and inactivated derivatives	232
645477644	316	27.48	1	300	1	294	8.0e-35	141	COG0583	DNA-binding transcriptional regulator, LysR family	297
645477649	213	38.86	3	210	1	201	2.0e-48	185	COG0461	Orotate phosphoribosyltransferase	201
645477651	435	37.31	22	283	1	265	2.0e-56	213	COG0548	Acetylglutamate kinase	265
645477653	207	37.44	3	197	79	289	2.0e-46	179	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
645477654	190	39.34	1	182	1	182	7.0e-34	136	COG2119	Putative Ca2+/H+ antiporter, TMEM165/GDT1 family	190
645477657	494	50.66	26	474	2	452	0.0e+00	524	COG1115	Na+/alanine symporter	452
645477660	259	32.34	58	255	20	212	2.0e-24	106	COG4912	3-methyladenine DNA glycosylase AlkD	222
645477669	247	18.77	1	242	5	248	1.0e-11	63.9	COG0631	Serine/threonine protein phosphatase PrpC	262
645477671	364	26.92	1	342	4	365	8.0e-31	128	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
645477672	152	26.85	5	152	35	182	5.0e-18	83.9	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
645477674	205	40.61	9	205	14	208	1.0e-52	199	COG0352	Thiamine monophosphate synthase	211
645477675	339	36.28	1	335	1	325	4.0e-56	212	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
645477676	101	51.04	1	96	13	107	3.0e-28	116	COG1733	DNA-binding transcriptional regulator, HxlR family	120
645477677	64	45.45	1	64	3	68	9.0e-11	58.3	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
645477678	262	52.71	1	258	7	262	4.0e-101	361	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
645477679	197	56.92	6	197	1	195	3.0e-62	231	COG0164	Ribonuclease HII	199
645477682	147	37.04	8	142	5	138	1.0e-26	112	COG3787	Uncharacterized conserved protein YhbP, UPF0306 family	145
645477684	108	37.27	1	108	1	110	5.0e-19	86.1	COG0607	Rhodanese-related sulfurtransferase	110
645477685	218	39.23	6	213	1	209	3.0e-58	218	COG2518	Protein-L-isoaspartate O-methyltransferase	209
645477686	169	50	1	165	1	163	9.0e-55	206	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
645477687	257	46.83	10	257	3	250	3.0e-74	272	COG0149	Triosephosphate isomerase	251
645477688	120	40.96	4	86	2	80	7.0e-15	72.9	COG1314	Preprotein translocase subunit SecG	86
645477694	299	23.53	52	270	11	210	9.0e-15	74.5	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
645477696	261	40.31	60	250	1	190	2.0e-37	149	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
645477699	240	37.8	73	236	11	170	3.0e-35	142	COG3721	Putative heme iron utilization protein	176
645477707	132	25.9	1	130	1	137	8.0e-16	76.2	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
645477710	357	21.62	1	357	1	354	8.0e-39	154	COG3203	Outer membrane protein (porin)	354
645477712	272	47.1	13	271	1	258	1.0e-85	309	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
645477713	841	19.39	2	839	30	754	1.0e-33	138	COG3170	Tfp pilus assembly protein FimV	755
645477714	177	43.02	1	177	1	178	2.0e-41	162	COG2917	Intracellular septation protein A	180
645477715	96	53.76	3	95	2	92	2.0e-21	93.8	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
645477716	89	43.33	1	89	2	89	2.0e-16	77.3	COG0271	Stress-induced morphogen (activity unknown)	90
645477717	287	16.85	8	284	21	297	4.0e-06	45.9	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
645477719	385	42.93	3	384	9	396	1.0e-86	313	COG3213	Uncharacterized protein involved in response to NO	396
645477722	154	39.86	1	146	1	148	1.0e-30	125	COG1959	DNA-binding transcriptional regulator, IscR family	150
645477724	324	22.31	82	323	44	237	2.0e-08	54	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
645477725	219	38.03	7	219	2	214	2.0e-40	159	COG0811	Biopolymer transport protein ExbB/TolQ	216
645477726	145	40.28	1	144	1	136	2.0e-30	124	COG0848	Biopolymer transport protein ExbD	137
645477732	510	25.1	19	502	6	519	1.0e-34	141	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
645477733	180	58	10	159	1	150	2.0e-51	195	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
645477735	122	45.87	3	111	7	115	2.0e-25	107	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
645477736	162	45.28	1	158	2	159	6.0e-31	126	COG1267	Phosphatidylglycerophosphatase A	160
645477737	321	46.25	4	320	3	317	1.0e-90	326	COG0611	Thiamine monophosphate kinase	317
645477738	270	32.2	8	267	4	255	2.0e-61	229	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
645477740	447	36.08	11	432	1	403	0.0e+00	472	COG0137	Argininosuccinate synthase	403
645477742	210	29.63	1	203	1	216	2.0e-36	145	COG2323	Uncharacterized membrane protein YcaP, DUF421 family	224
645477743	123	41.03	1	115	1	114	4.0e-22	96.5	COG3189	Uncharacterized conserved protein YeaO, DUF488 family	117
645477745	491	34.6	3	472	2	429	1.0e-106	380	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
645477748	195	32.58	52	182	56	186	4.0e-17	81.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
645477749	196	37.95	2	194	1	191	4.0e-39	154	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
645477751	242	56.72	1	238	1	237	2.0e-93	335	COG0052	Ribosomal protein S2	252
645477752	284	53.04	1	283	1	295	9.0e-83	300	COG0264	Translation elongation factor EF-Ts	296
645477754	301	59.66	65	301	1	238	1.0e-93	336	COG0528	Uridylate kinase	238
645477756	512	51.37	1	510	7	518	3.0e-125	442	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
645477757	620	17.07	14	618	2	696	5.0e-59	222	COG0557	Exoribonuclease R	706
645477760	118	58.47	1	118	4	121	4.0e-31	126	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
645477761	160	67.72	2	159	12	169	7.0e-74	269	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
645477762	197	44.69	1	179	3	171	1.0e-45	176	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
645477763	418	60.05	1	418	8	398	0.0e+00	623	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
645477764	157	46.5	1	157	4	157	4.0e-50	190	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
645477765	431	61.32	1	423	3	424	0.0e+00	654	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
645477767	118	56.88	7	115	12	120	1.0e-35	141	COG2852	Very-short-patch-repair endonuclease	129
645477769	753	40.83	1	713	1	693	0.0e+00	697	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
645477770	358	49.56	17	355	3	332	2.0e-96	346	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
645477771	159	45.73	1	159	3	161	3.0e-42	164	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
645477772	223	47.93	1	169	1	165	3.0e-32	131	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
645477773	101	61.39	1	101	1	100	1.0e-23	101	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
645477776	674	41.63	7	667	1	606	0.0e+00	486	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
645477778	101	36.96	1	92	1	92	6.0e-12	62.3	COG1605	Chorismate mutase	101
645477779	106	20	1	104	10	110	2.0e-08	50.4	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
645477782	498	52.81	2	497	1	490	0.0e+00	525	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
645477783	480	47.38	6	480	3	475	2.0e-100	359	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
645477786	153	63.09	1	149	1	145	3.0e-58	217	COG1490	D-Tyr-tRNAtyr deacylase	145
645477787	446	28.15	179	416	35	247	5.0e-19	89.3	COG0790	TPR repeat	292
645477789	728	23.7	7	453	3	458	9.0e-44	172	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
645477790	148	32.64	1	143	1	139	6.0e-30	123	COG0394	Protein-tyrosine-phosphatase	139
645477791	377	40.41	48	292	6	239	2.0e-43	170	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
645477795	391	42.93	8	389	9	374	6.0e-118	417	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
645477796	260	27.55	1	244	1	253	1.0e-29	123	COG0223	Methionyl-tRNA formyltransferase	307
645477797	236	22.55	5	225	1	227	9.0e-19	87.3	COG1011	FMN phosphatase YigB, HAD superfamily	229
645477799	205	50.79	1	184	36	224	7.0e-65	240	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
645477802	357	22.37	1	356	2	375	9.0e-28	117	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
645477804	366	31.21	72	355	47	344	8.0e-33	134	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
645477805	477	23.3	3	453	9	460	7.0e-13	69	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
645477806	439	45.92	10	432	2	426	0.0e+00	509	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
645477808	365	67.12	1	146	1	146	1.0e-59	223	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
645477810	122	52.07	2	122	33	153	1.0e-39	154	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
645477814	395	30.56	120	394	1	281	5.0e-31	128	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
645477815	651	26.48	1	620	1	478	2.0e-100	360	COG1333	Cytochrome c biogenesis protein ResB	478
645477816	208	46.03	1	126	1	121	2.0e-26	112	COG2863	Cytochrome c553	121
645477817	217	49.75	1	196	1	196	3.0e-63	234	COG0218	GTP-binding protein EngB required for normal cell division	200
645477821	369	41.48	21	369	6	353	1.0e-81	296	COG4972	Tfp pilus assembly protein, ATPase PilM	354
645477822	205	26.6	6	193	6	191	2.0e-25	109	COG3166	Tfp pilus assembly protein PilN	206
645477823	230	41.78	8	215	5	211	2.0e-46	179	COG3167	Tfp pilus assembly protein PilO	211
645477824	164	40.28	2	143	27	170	7.0e-33	133	COG3168	Tfp pilus assembly protein PilP	170
645477825	711	32.64	45	703	44	708	3.0e-106	380	COG4796	Type II secretory pathway, component HofQ	709
645477826	173	49.68	8	164	2	158	9.0e-52	196	COG0703	Shikimate kinase	172
645477827	359	58.06	1	359	1	358	0.0e+00	477	COG0337	3-dehydroquinate synthetase	360
645477829	170	64.02	1	164	15	172	5.0e-50	190	COG3198	Uncharacterized protein	172
645477831	186	43.85	1	186	10	189	1.0e-21	96.2	COG0558	Phosphatidylglycerophosphate synthase	192
645477836	352	22.86	94	316	49	289	3.0e-13	69.9	COG4974	Site-specific recombinase XerD	300
645477850	218	21.26	20	209	8	194	2.0e-12	66.5	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
645477855	134	25	4	120	2	121	2.0e-09	55	COG5611	Predicted nucleic-acid-binding protein, contains PIN domain	130
645477863	423	26.76	7	366	1	354	5.0e-47	182	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
645477866	208	26.36	4	208	3	210	8.0e-12	64	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
645477868	920	14.68	9	869	30	754	2.0e-15	78.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
645477869	141	35.04	1	136	3	130	5.0e-18	83.7	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
645477870	91	40	16	75	1	60	8.0e-07	45.4	COG4691	Plasmid stability protein	80
645477874	1008	28.92	98	381	92	348	4.0e-24	107	COG4643	Uncharacterized domain associated with phage/plasmid primase	366
645477876	683	30.2	8	603	30	585	1.0e-86	314	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
645477877	134	26.32	4	134	3	135	5.0e-18	83.6	COG0629	Single-stranded DNA-binding protein	167
645477880	365	28.88	17	338	17	289	1.0e-39	157	COG0630	Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase	312
645477881	409	28.48	98	402	69	357	2.0e-44	173	COG2948	Type IV secretory pathway, VirB10 components	360
645477882	279	27.11	1	273	4	258	2.0e-30	126	COG3504	Type IV secretory pathway, VirB9 components	265
645477883	246	31.2	13	243	5	232	2.0e-33	135	COG3736	Type IV secretory pathway, component VirB8	239
645477890	760	31.08	4	755	35	792	8.0e-95	341	COG3451	Type IV secretory pathway, VirB4 component	796
645477895	761	64.58	11	759	10	754	0.0e+00	1086	COG1882	Pyruvate-formate lyase	755
645477896	270	33.74	26	270	18	257	2.0e-61	229	COG1180	Pyruvate-formate lyase-activating enzyme	260
645477899	601	39.9	1	599	1	567	0.0e+00	527	COG4232	Thiol:disulfide interchange protein	569
645477901	277	42.4	21	277	2	283	1.0e-72	266	COG1469	GTP cyclohydrolase FolE2	289
645477902	385	47.72	1	385	6	396	0.0e+00	472	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
645477903	152	21.19	1	148	1	135	5.0e-09	53.9	COG3187	Heat shock protein HslJ	142
645477904	259	25.65	5	259	1	266	1.0e-37	150	COG1018	Ferredoxin-NADP reductase	266
645477908	169	47.37	1	169	1	157	4.0e-49	187	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
645477909	471	30.42	30	471	6	457	2.0e-61	230	COG0471	Di- and tricarboxylate transporter	461
645477912	255	45.76	16	251	2	231	2.0e-61	229	COG0710	3-dehydroquinate dehydratase	231
645477915	105	74.23	1	97	20	116	2.0e-37	147	COG0203	Ribosomal protein L17	116
645477916	278	49.82	1	276	44	317	2.0e-77	282	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
645477917	206	60.58	1	206	1	205	8.0e-62	229	COG0522	Ribosomal protein S4 or related protein	205
645477918	131	64.84	4	131	2	129	5.0e-46	176	COG0100	Ribosomal protein S11	129
645477919	120	64.46	1	120	1	121	4.0e-42	162	COG0099	Ribosomal protein S13	121
645477920	72	61.11	1	72	1	72	1.0e-24	104	COG0361	Translation initiation factor IF-1	75
645477921	448	49.42	15	437	7	431	2.0e-115	409	COG0201	Preprotein translocase subunit SecY	436
645477922	144	52	1	144	1	150	1.0e-31	128	COG0200	Ribosomal protein L15	152
645477923	61	50	7	60	1	54	2.0e-11	60.9	COG1841	Ribosomal protein L30/L7E	55
645477924	172	58.43	5	169	16	181	4.0e-55	207	COG0098	Ribosomal protein S5	181
645477925	117	50	1	117	6	125	2.0e-27	114	COG0256	Ribosomal protein L18	125
645477926	177	54.24	1	176	1	176	8.0e-58	216	COG0097	Ribosomal protein L6P/L9E	178
645477927	130	65.65	1	129	1	131	8.0e-46	175	COG0096	Ribosomal protein S8	132
645477928	101	59.02	41	101	1	61	6.0e-16	75.6	COG0199	Ribosomal protein S14	61
645477929	179	67.04	1	179	1	179	8.0e-76	276	COG0094	Ribosomal protein L5	180
645477930	107	53.27	1	106	2	104	4.0e-17	79.6	COG0198	Ribosomal protein L24	104
645477931	104	74.75	1	99	1	99	5.0e-39	152	COG0093	Ribosomal protein L14	122
645477932	87	62.35	1	85	2	86	3.0e-23	100	COG0186	Ribosomal protein S17	87
645477933	63	51.61	2	63	4	65	1.0e-09	54.9	COG0255	Ribosomal protein L29	69
645477934	138	63.5	1	135	2	138	7.0e-46	176	COG0197	Ribosomal protein L16/L10AE	146
645477935	231	55.56	12	229	1	225	7.0e-76	277	COG0092	Ribosomal protein S3	233
645477936	109	63.89	1	108	9	116	7.0e-34	135	COG0091	Ribosomal protein L22	120
645477937	92	67.39	1	92	1	92	6.0e-37	145	COG0185	Ribosomal protein S19	93
645477938	277	59.34	1	272	1	273	2.0e-106	379	COG0090	Ribosomal protein L2	275
645477939	106	54.26	8	100	1	94	6.0e-23	99.1	COG0089	Ribosomal protein L23	94
645477940	206	41.43	1	206	2	211	5.0e-57	214	COG0088	Ribosomal protein L4	214
645477941	238	59.35	26	238	1	214	2.0e-74	272	COG0087	Ribosomal protein L3	218
645477945	503	49.79	23	502	2	477	0.0e+00	543	COG0469	Pyruvate kinase	477
645477947	470	32.26	6	469	5	440	7.0e-94	338	COG2067	Long-chain fatty acid transport protein	440
645477951	278	38.74	1	271	7	308	3.0e-50	192	COG0672	High-affinity Fe2+/Pb2+ permease	383
645477952	393	65.69	19	393	1	376	0.0e+00	476	COG2822	Iron uptake system EfeUOB, periplasmic (or lipoprotein) component EfeO/EfeM	376
645477954	473	42.15	93	471	7	350	3.0e-91	329	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
645477965	138	55	20	138	1	120	1.0e-24	105	COG1734	RNA polymerase-binding transcription factor DksA	120
645477968	265	41.95	1	261	2	266	3.0e-65	241	COG0345	Pyrroline-5-carboxylate reductase	266
645477970	235	52.4	2	229	1	228	3.0e-81	294	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
645477971	348	63.87	1	346	3	348	0.0e+00	530	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
645477972	410	56.58	31	410	1	375	0.0e+00	511	COG5008	Tfp pilus assembly protein, ATPase PilU	375
645477973	278	39.25	57	269	1	204	5.0e-44	171	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
645477977	178	20.5	1	177	1	199	6.0e-06	43.8	COG3637	Opacity protein and related surface antigens	199
645477978	1012	52.75	3	491	1	487	0.0e+00	527	COG1530	Ribonuclease G or E	487
645477986	207	47.87	4	206	2	212	7.0e-58	217	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
645477992	269	48.69	5	269	4	268	4.0e-81	294	COG0796	Glutamate racemase	269
645477994	158	46.21	9	152	3	147	6.0e-46	176	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
645477995	419	36.07	171	414	21	231	6.0e-54	205	COG0860	N-acetylmuramoyl-L-alanine amidase	231
645477997	570	33.33	1	554	8	537	1.0e-56	214	COG2268	Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain	548
645478002	160	24.52	4	155	5	143	7.0e-21	93.5	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
645478006	220	22.79	8	218	6	218	2.0e-08	52.6	COG1842	Phage shock protein A	225
645478010	952	57.28	352	952	2	593	0.0e+00	774	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
645478015	167	37.37	49	147	16	111	2.0e-09	55.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
645478016	268	27.99	22	267	23	284	1.0e-16	80.9	COG0790	TPR repeat	292
645478020	379	30.07	1	373	1	432	2.0e-84	306	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
645478021	219	26.89	13	219	1	212	1.0e-39	156	COG1186	Protein chain release factor B	239
645478023	379	53.66	4	372	8	367	0.0e+00	480	COG2021	Homoserine acetyltransferase	368
645478027	379	28.79	29	350	1	322	1.0e-50	194	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
645478028	295	46.01	3	277	6	267	6.0e-60	224	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
645478029	321	42.49	9	321	2	287	2.0e-71	262	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
645478030	420	48.34	54	414	1	346	7.0e-122	430	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
645478032	226	52.68	1	224	1	224	8.0e-70	256	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
645478042	169	37.11	5	163	1	158	1.0e-61	229	COG4899	Uncharacterized protein	166
645478044	492	57.52	1	492	1	475	0.0e+00	671	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
645478045	174	36.46	1	174	2	180	2.0e-22	99.3	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
645478046	662	41.19	1	397	2	397	9.0e-64	238	COG0475	Kef-type K+ transport system, membrane component KefB	397
645478051	208	34.91	26	206	1	212	4.0e-23	101	COG2755	Lysophospholipase L1 or related esterase	216
645478053	183	41.58	1	171	1	185	2.0e-48	185	COG2818	3-methyladenine DNA glycosylase Tag	188
645478054	133	64.34	6	133	1	129	1.0e-43	168	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
645478055	366	45.29	1	364	2	376	2.0e-102	366	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
645478057	160	40.26	1	154	1	154	2.0e-39	154	COG1522	DNA-binding transcriptional regulator, Lrp family	154
645478060	119	50.42	1	119	1	119	4.0e-30	123	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
645478062	206	41.55	2	206	1	206	5.0e-58	217	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
645478064	248	41.49	7	247	10	222	2.0e-50	192	COG0765	ABC-type amino acid transport system, permease component	222
645478066	450	42.5	1	398	4	346	1.0e-105	377	COG0826	Collagenase-like protease, PrtC family	347
645478068	245	60.41	1	245	1	245	8.0e-101	359	COG1135	ABC-type methionine transport system, ATPase component	339
645478069	228	55.4	16	228	10	222	1.0e-64	239	COG2011	ABC-type methionine transport system, permease component	222
645478071	318	46.62	4	281	2	267	7.0e-76	277	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
645478072	166	36.84	52	145	1	95	8.0e-10	56.6	COG3335	Transposase	132
645478075	538	18.37	63	534	2	444	2.0e-06	47.6	COG1232	Protoporphyrinogen oxidase	444
645478078	404	32.06	1	400	1	409	3.0e-67	249	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
645478080	413	23.48	5	358	3	346	9.0e-35	141	COG0644	Dehydrogenase (flavoprotein)	396
645478085	247	61.54	21	228	1	204	9.0e-88	316	COG1636	Predicted ATPase, Adenine nucleotide alpha hydrolases (AANH) superfamily	204
645478087	203	52	1	197	3	200	1.0e-48	185	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
645478088	133	35.04	18	132	2	118	3.0e-26	110	COG1539	Dihydroneopterin aldolase	121
645478089	177	24	40	175	9	156	3.0e-08	51.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
645478092	1277	21.71	866	1257	2	388	2.0e-46	182	COG0247	Fe-S oxidoreductase	388
645478105	245	57.74	10	245	1	238	3.0e-81	295	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
645478108	143	55.08	5	121	1	118	2.0e-39	154	COG3536	Uncharacterized conserved protein, DUF971 family	120
645478113	94	51.69	5	93	1	89	2.0e-24	104	COG1534	RNA-binding protein YhbY	97
645478114	184	55.98	1	184	19	202	1.0e-67	249	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
645478118	1213	30.13	6	1177	4	1123	0.0e+00	567	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
645478119	72	61.11	1	72	1	72	1.0e-18	84.6	COG2841	Uncharacterized conserved protein YdcH, DUF465 family	72
645478121	919	39.8	1	919	10	784	0.0e+00	729	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
645478122	162	29.94	1	159	1	156	6.0e-31	126	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
645478123	546	38.93	395	543	43	190	1.0e-31	131	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
645478125	448	30.96	1	445	2	444	9.0e-81	294	COG3522	Predicted component of the type VI protein secretion system	446
645478126	165	41.72	2	162	4	166	4.0e-39	154	COG3516	Predicted component of the type VI protein secretion system	169
645478127	509	49.61	2	508	4	494	0.0e+00	661	COG3517	Predicted component of the type VI protein secretion system	495
645478128	521	69.44	198	521	2	315	0.0e+00	552	COG0519	GMP synthase, PP-ATPase domain/subunit	315
645478131	148	58.78	1	148	6	152	1.0e-51	195	COG0691	tmRNA-binding protein	153
645478134	173	45.28	65	170	9	114	2.0e-33	135	COG1733	DNA-binding transcriptional regulator, HxlR family	120
645478135	290	38.49	1	287	1	276	5.0e-62	231	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
645478136	164	59.49	1	157	1	158	1.0e-61	228	COG2077	Peroxiredoxin	158
645478138	301	64.65	3	297	7	303	1.0e-130	459	COG0408	Coproporphyrinogen III oxidase	303
645478139	243	51.33	89	237	2	151	2.0e-46	178	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
645478140	313	50.34	4	299	3	295	9.0e-96	343	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
645478142	193	56.28	1	193	2	200	1.0e-72	265	COG0605	Superoxide dismutase	204
645478143	457	42.3	1	455	27	485	4.0e-120	424	COG0513	Superfamily II DNA and RNA helicase	513
645478145	315	39.94	1	313	69	387	6.0e-92	330	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
645478146	279	51.72	1	278	1	290	1.0e-97	349	COG2321	Predicted metalloprotease	295
645478147	460	33.77	8	452	9	459	3.0e-101	362	COG1109	Phosphomannomutase	464
645478150	660	21.32	142	621	26	491	5.0e-37	149	COG0366	Glycosidase	505
645478152	472	20.8	9	428	2	366	2.0e-13	71	COG2814	Predicted arabinose efflux permease, MFS family	394
645478156	178	43.75	33	173	54	197	3.0e-31	128	COG0791	Cell wall-associated hydrolase, NlpC family	197
645478157	206	72.36	8	206	2	198	6.0e-88	316	COG0740	ATP-dependent protease ClpP, protease subunit	200
645478158	436	41.31	1	436	1	441	1.0e-96	347	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
645478159	815	32.96	56	815	89	858	0.0e+00	483	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
645478160	266	44.24	6	215	24	239	3.0e-58	218	COG0688	Phosphatidylserine decarboxylase	239
645478162	519	28.39	55	518	1	449	2.0e-48	187	COG1538	Outer membrane protein TolC	457
645478177	198	28.79	1	198	47	231	1.0e-16	80	COG2801	Transposase InsO and inactivated derivatives	232
645478178	331	37.94	1	331	4	340	4.0e-96	344	COG1559	Cell division protein YceG, involved in septum cleavage	342
645478184	289	59.86	1	287	1	288	8.0e-124	436	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
645478186	193	33.33	1	190	3	186	1.0e-35	143	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
645478187	620	32.38	24	617	2	573	8.0e-130	457	COG3850	Signal transduction histidine kinase, nitrate/nitrite-specific	574
645478188	218	43.19	3	215	1	211	1.0e-53	202	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
645478192	197	59.28	3	195	1	193	4.0e-72	264	COG0807	GTP cyclohydrolase II	193
645478196	563	18.36	9	557	1	459	1.0e-51	198	COG0277	FAD/FMN-containing dehydrogenase	459
645478197	439	29.65	14	438	4	415	2.0e-63	237	COG2733	Uncharacterized membrane-anchored protein YjiN, DUF445 family	415
645478199	485	40.57	4	485	3	488	7.0e-86	311	COG0168	Trk-type K+ transport system, membrane component	499
645478200	439	21.15	38	436	49	446	9.0e-15	75.2	COG2271	Sugar phosphate permease	448
645478201	243	24.14	40	232	46	226	2.0e-07	49.5	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
645478202	219	25.23	5	219	2	206	1.0e-26	113	COG0778	Nitroreductase	207
645478203	375	29.23	8	348	2	342	9.0e-52	197	COG0673	Predicted dehydrogenase	342
645478208	159	29.37	33	158	1	126	6.0e-18	83.6	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
645478209	231	37.72	1	228	3	230	3.0e-47	182	COG1346	Putative effector of murein hydrolase	230
645478211	334	30.56	14	334	6	323	6.0e-60	224	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
645478212	326	27.06	2	325	1	309	1.0e-36	147	COG0451	Nucleoside-diphosphate-sugar epimerase	314
645478214	428	22.63	17	373	16	377	2.0e-42	166	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
645478218	544	56.48	6	542	2	525	0.0e+00	642	COG4650	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain	531
645478219	251	31.95	9	241	7	241	1.0e-40	160	COG4021	tRNA(His) 5'-end guanylyltransferase	249
645478228	147	32.21	1	145	1	147	1.0e-21	95.7	COG0698	Ribose 5-phosphate isomerase RpiB	151
645478229	231	30.56	1	169	3	165	8.0e-23	100	COG4186	Calcineurin-like phosphoesterase superfamily protein	186
645478230	117	31.03	3	117	1	116	1.0e-09	55.4	COG3335	Transposase	132
645478233	456	60.96	1	455	1	451	0.0e+00	616	COG0541	Signal recognition particle GTPase	451
645478235	71	54.79	1	71	1	73	8.0e-21	91.9	COG0254	Ribosomal protein L31	75
645478237	177	36.13	28	177	27	181	7.0e-23	100	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
645478238	483	56.96	11	483	1	464	0.0e+00	671	COG0215	Cysteinyl-tRNA synthetase	464
645478239	259	37.25	8	249	2	228	6.0e-34	137	COG4271	Predicted nucleotide-binding protein containing TIR -like domain	233
645478241	386	56.69	1	376	1	365	0.0e+00	510	COG0536	GTPase involved in cell partioning and DNA repair	369
645478242	232	19.61	20	222	46	244	1.0e-07	50.6	COG1651	Protein-disulfide isomerase	244
645478244	335	36.26	63	332	1	230	6.0e-43	168	COG3039	Transposase and inactivated derivatives, IS5 family	230
645478247	119	48.74	1	119	1	119	2.0e-27	114	COG2018	Predicted regulator of Ras-like GTPase activity, Roadblock/LC7/MglB family	119
645478249	178	42.22	1	178	8	185	6.0e-44	170	COG2229	Signal recognition particle receptor subunit beta, a GTPase	187
645478258	273	76.1	1	272	31	298	0.0e+00	502	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
645478261	470	40.79	17	468	4	442	1.0e-100	360	COG3182	Uncharacterized iron-regulated membrane protein	442
645478267	141	47.41	1	135	1	135	2.0e-31	128	COG0355	FoF1-type ATP synthase, epsilon subunit	135
645478268	465	75.58	1	465	1	466	0.0e+00	830	COG0055	FoF1-type ATP synthase, beta subunit	468
645478269	291	50.17	5	291	1	286	4.0e-95	341	COG0224	FoF1-type ATP synthase, gamma subunit	287
645478270	515	66.6	1	515	1	504	0.0e+00	811	COG0056	FoF1-type ATP synthase, alpha subunit	504
645478271	177	38.2	1	176	1	178	2.0e-36	144	COG0712	FoF1-type ATP synthase, delta subunit	178
645478272	156	43.14	4	156	6	158	9.0e-17	79.5	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
645478274	289	36	15	289	3	246	3.0e-45	175	COG0356	FoF1-type ATP synthase, membrane subunit a	246
645478275	147	31.09	31	147	11	128	5.0e-08	50.2	COG3312	FoF1-type ATP synthase assembly protein I	128
645478276	295	48.54	17	289	6	275	2.0e-86	312	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
645478277	115	48.65	6	115	3	113	3.0e-34	136	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
645478278	197	60.34	4	182	1	176	1.0e-65	242	COG0279	Phosphoheptose isomerase	176
645478279	203	37.06	6	200	6	196	2.0e-35	142	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
645478285	945	52.09	1	945	1	877	0.0e+00	1177	COG0525	Valyl-tRNA synthetase	877
645478288	251	47.04	1	247	3	254	4.0e-65	241	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
645478290	158	37.5	13	148	21	155	2.0e-26	111	COG0315	Molybdenum cofactor biosynthesis enzyme	157
645478291	900	49.34	6	900	1	910	0.0e+00	1089	COG2352	Phosphoenolpyruvate carboxylase	910
645478292	315	30.25	1	301	1	285	2.0e-22	99.6	COG3547	Transposase	303
645478296	701	64.58	1	701	1	693	0.0e+00	988	COG0480	Translation elongation factor EF-G, a GTPase	697
645478297	156	62.84	2	149	1	148	3.0e-54	203	COG0049	Ribosomal protein S7	148
645478298	117	75	2	117	14	129	3.0e-45	173	COG0048	Ribosomal protein S12	129
645478300	1391	50.23	15	853	1	806	0.0e+00	893	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
645478302	123	72.58	1	123	1	124	4.0e-28	116	COG0222	Ribosomal protein L7/L12	124
645478303	166	43.45	1	166	1	168	9.0e-33	133	COG0244	Ribosomal protein L10	175
645478304	184	62.98	1	180	48	228	2.0e-65	241	COG0081	Ribosomal protein L1	228
645478306	144	71.83	2	143	1	141	5.0e-54	203	COG0080	Ribosomal protein L11	141
645478307	177	54.8	1	177	1	177	5.0e-55	207	COG0250	Transcription antitermination factor NusG	178
645478308	90	36.84	26	82	15	71	4.0e-10	56.6	COG0690	Preprotein translocase subunit SecE	73
645478310	394	85.28	1	394	1	394	0.0e+00	732	COG0050	Translation elongation factor EF-Tu, a GTPase	394
645478315	188	43.24	10	183	1	185	6.0e-46	176	COG0742	16S rRNA G966 N2-methylase RsmD	187
645478319	790	52.61	25	591	1	555	0.0e+00	675	COG0550	DNA topoisomerase IA	570
645478320	151	35.46	1	135	1	141	9.0e-36	142	COG2922	Uncharacterized conserved protein Smg, DUF494 family	157
645478321	403	48.16	1	299	1	293	1.0e-90	326	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
645478322	427	31.13	1	422	2	464	4.0e-91	328	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
645478323	707	38.36	1	700	7	707	0.0e+00	668	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
645478325	419	37.78	94	418	3	353	4.0e-79	288	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
645478328	173	54.19	1	173	2	179	1.0e-46	178	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
645478329	308	52.92	1	306	2	307	2.0e-106	379	COG0223	Methionyl-tRNA formyltransferase	307
645478330	193	51.79	27	190	1	168	1.0e-57	215	COG0242	Peptide deformylase	168
645478335	228	31.17	1	228	5	233	1.0e-22	99	COG0670	Integral membrane protein, interacts with FtsH	233
645478340	266	55.98	1	258	3	261	9.0e-103	366	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
645478341	258	48.44	1	256	9	263	4.0e-63	235	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
645478343	196	39.3	1	193	3	202	1.0e-46	179	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
645478344	92	40	1	92	5	98	4.0e-21	93	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
645478351	92	44.71	2	86	1	85	1.0e-19	88	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
645478352	296	26.6	3	295	2	296	5.0e-29	121	COG0583	DNA-binding transcriptional regulator, LysR family	297
645478354	218	40.55	1	216	1	210	8.0e-48	183	COG2910	Putative NADH-flavin reductase	211
645478362	279	25.81	3	278	14	291	5.0e-29	121	COG0583	DNA-binding transcriptional regulator, LysR family	297
645478364	287	30.56	2	287	1	286	6.0e-50	191	COG1562	Phytoene/squalene synthetase	288
645478367	172	35.67	1	157	2	158	8.0e-29	120	COG1510	DNA-binding transcriptional regulator GbsR, MarR family	177
645478370	160	41.4	4	160	3	154	6.0e-26	110	COG5528	Uncharacterized membrane protein	155
645478371	279	26.91	1	211	1	218	1.0e-16	80.7	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
645478373	318	61.44	1	318	13	329	0.0e+00	502	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
645478374	470	29.21	211	465	42	281	5.0e-22	99.4	COG0790	TPR repeat	292
645478376	771	21.31	78	771	41	768	4.0e-31	130	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
645478377	589	39.53	14	588	1	591	0.0e+00	546	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
645478378	436	25.34	1	432	1	438	5.0e-35	142	COG4487	Uncharacterized protein	438
645478384	389	24.67	15	387	14	336	3.0e-51	195	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
645478386	395	33.67	4	390	3	385	2.0e-78	286	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
645478387	259	61.09	1	257	1	253	5.0e-92	330	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
645478390	226	49.33	5	226	1	223	2.0e-74	272	COG1136	ABC-type lipoprotein export system, ATPase component	226
645478392	375	46.6	3	325	4	323	6.0e-86	311	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
645478395	201	49.24	3	199	2	198	2.0e-70	258	COG0353	Recombinational DNA repair protein RecR	198
645478398	116	36.44	1	116	2	117	6.0e-30	122	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
645478400	284	34.18	1	271	15	288	2.0e-53	202	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
645478401	447	41.23	1	447	15	468	7.0e-111	394	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
645478408	118	43.48	5	118	4	117	3.0e-34	136	COG3215	Tfp pilus assembly protein PilZ	117
645478409	258	48.05	1	252	1	256	9.0e-82	296	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
645478411	221	50.23	2	209	1	208	4.0e-40	158	COG2836	Sulfite exporter TauE/SafE	232
645478412	509	56.01	1	508	127	624	0.0e+00	669	COG1154	Deoxyxylulose-5-phosphate synthase	627
645478415	218	56.99	18	203	2	186	2.0e-69	255	COG0194	Guanylate kinase	191
645478416	68	52.17	1	68	1	69	8.0e-13	65.3	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
645478423	70	62.5	1	64	1	64	4.0e-06	43.3	COG0828	Ribosomal protein S21	67
645478425	148	56.76	1	147	1	148	3.0e-38	150	COG1610	Uncharacterized conserved protein YqeY	148
645478429	65	48	1	50	1	50	4.0e-14	69.9	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
645478437	247	42.34	9	245	3	237	3.0e-56	211	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
645478438	171	26.17	24	171	35	182	3.0e-18	85.1	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
645478439	416	46.09	69	409	1	339	2.0e-107	382	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
645478440	507	45.28	28	501	1	471	0.0e+00	508	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
645478442	269	27.57	1	265	1	252	3.0e-15	76.2	COG0730	Uncharacterized membrane protein YfcA	258
645478443	254	41.78	16	238	4	225	2.0e-47	183	COG1183	Phosphatidylserine synthase	234
645478444	917	56.88	2	910	1	822	0.0e+00	1093	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
645478447	195	72	48	195	2	151	9.0e-49	186	COG3241	Azurin	151
645478450	411	35.05	23	408	2	409	1.0e-83	303	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
645478452	271	27.93	150	259	17	127	2.0e-15	76.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
645478453	197	45.05	16	197	3	173	3.0e-43	168	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
645478454	269	44.31	99	262	2	168	2.0e-43	169	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
645478456	342	59.21	11	341	1	310	0.0e+00	460	COG0078	Ornithine carbamoyltransferase	310
645478461	79	45	2	76	1	80	2.0e-16	77.4	COG3042	Putative hemolysin	85
645478466	352	19.83	8	348	14	339	5.0e-11	62.6	COG0628	Predicted PurR-regulated permease PerM	355
645478469	317	47.08	1	306	1	302	3.0e-93	335	COG0196	FAD synthase	304
645478470	326	39.39	1	326	1	318	4.0e-58	218	COG4255	Uncharacterized protein	318
645478471	407	38.43	164	377	57	270	1.0e-38	154	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
645478473	77	71.43	1	76	1	77	2.0e-21	94.2	COG0227	Ribosomal protein L28	77
645478474	51	59.18	1	49	2	50	6.0e-10	56	COG0267	Ribosomal protein L33	50
645478477	366	38.61	19	329	1	313	6.0e-78	284	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
645478478	109	43.68	23	109	6	90	3.0e-19	86.8	COG1862	Preprotein translocase subunit YajC	97
645478479	617	50.57	76	596	2	501	0.0e+00	492	COG0342	Preprotein translocase subunit SecD	506
645478480	311	46.28	1	308	1	305	2.0e-81	296	COG0341	Preprotein translocase subunit SecF	305
645478481	185	28.57	1	180	3	198	6.0e-20	90.8	COG0778	Nitroreductase	207
645478482	315	27.48	24	313	1	308	1.0e-38	154	COG0524	Sugar or nucleoside kinase, ribokinase family	311
645478484	566	43.94	36	535	1	477	9.0e-114	404	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
645478486	176	48.84	1	167	15	186	4.0e-54	204	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
645478488	453	35.56	27	453	8	454	1.0e-93	337	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
645478489	89	58.43	1	89	1	89	3.0e-28	116	COG0184	Ribosomal protein S15P/S13E	89
645478491	180	52.51	2	180	1	160	2.0e-64	238	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
645478493	156	31.88	1	156	2	156	6.0e-23	100	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
645478494	299	53.03	39	299	1	264	6.0e-89	320	COG0159	Tryptophan synthase alpha chain	265
645478495	291	59.93	1	282	1	281	2.0e-121	428	COG0777	Acetyl-CoA carboxylase beta subunit	294
645478496	614	30.07	309	605	1	296	2.0e-26	114	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
645478497	186	49.41	10	179	5	174	4.0e-44	170	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
645478500	300	38.26	5	300	1	311	7.0e-52	197	COG0524	Sugar or nucleoside kinase, ribokinase family	311
645478501	284	36.24	2	281	1	262	7.0e-53	201	COG0388	Predicted amidohydrolase	274
645478504	950	58.22	443	921	10	496	0.0e+00	705	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
645478505	296	30.74	38	278	2	241	1.0e-44	174	COG2186	DNA-binding transcriptional regulator, FadR family	241
645478506	547	57.22	14	541	1	522	0.0e+00	517	COG1620	L-lactate permease	522
645478510	162	33.78	13	158	1	139	1.0e-24	106	COG4968	Tfp pilus assembly protein PilE	139
645478511	156	46.45	1	155	1	155	1.0e-54	205	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
645478512	128	46.49	7	119	1	114	1.0e-29	121	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
645478513	203	39.71	1	201	2	197	1.0e-52	199	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
645478514	198	35.15	1	186	1	200	7.0e-39	153	COG0288	Carbonic anhydrase	207
645478518	312	39.94	1	310	5	352	6.0e-85	307	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
645478519	480	45.61	5	480	2	471	0.0e+00	495	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
645478520	558	56.02	232	395	4	169	3.0e-68	253	COG0225	Peptide methionine sulfoxide reductase MsrA	174
645478521	524	38.97	94	501	25	422	7.0e-84	304	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
645478528	237	40.54	33	237	1	221	1.0e-45	176	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
645478529	417	66.67	1	417	1	420	0.0e+00	636	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
645478531	432	28.11	6	432	1	431	1.0e-61	231	COG0612	Predicted Zn-dependent peptidase	438
645478533	455	29.93	7	443	1	436	4.0e-70	259	COG0612	Predicted Zn-dependent peptidase	438
645478537	485	38.72	1	485	4	498	1.0e-105	377	COG3104	Dipeptide/tripeptide permease	498
645478539	874	46.48	1	867	1	842	0.0e+00	917	COG0249	DNA mismatch repair ATPase MutS	843
645478543	770	26.56	55	770	1	671	4.0e-110	392	COG1289	Uncharacterized membrane protein YccC	674
645478544	1402	26.1	24	1380	1	1278	0.0e+00	600	COG2911	Autotransporter translocation and assembly factor TamB	1278
645478546	194	41.67	61	191	7	137	6.0e-24	104	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
645478549	281	34.15	1	276	15	297	9.0e-38	150	COG0668	Small-conductance mechanosensitive channel	316
645478554	166	23.91	36	123	21	112	2.0e-06	45.7	COG0526	Thiol-disulfide isomerase or thioredoxin	127
645478556	119	40.71	6	118	4	115	1.0e-27	115	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
645478557	214	29.28	4	183	8	185	2.0e-20	92.6	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
645478558	464	40.38	2	462	9	466	0.0e+00	469	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
645478559	316	45.83	2	311	3	302	2.0e-80	292	COG4714	Uncharacterized membrane-anchored protein	303
645478560	834	62.48	43	604	2	563	0.0e+00	886	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
645478561	192	57.98	1	186	1	188	2.0e-74	271	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
645478562	285	40.96	27	273	3	238	1.0e-35	143	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
645478564	415	60.96	2	413	1	411	0.0e+00	487	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
645478565	78	62.34	1	77	3	79	4.0e-14	69.6	COG0236	Acyl carrier protein	80
645478568	673	47.24	3	671	1	648	0.0e+00	756	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
645478569	378	60.99	1	378	1	370	0.0e+00	498	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
645478571	878	52.04	3	878	1	814	0.0e+00	1069	COG0495	Leucyl-tRNA synthetase	814
645478577	406	48.05	2	406	1	404	0.0e+00	471	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
645478578	233	43.36	9	233	5	230	1.0e-54	206	COG1346	Putative effector of murein hydrolase	230
645478579	114	45.13	1	113	5	117	1.0e-20	91.7	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
645478582	210	35.93	36	198	31	197	9.0e-32	130	COG0791	Cell wall-associated hydrolase, NlpC family	197
645478584	547	33.27	9	517	4	514	6.0e-95	341	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
645478585	260	52.92	5	260	1	253	5.0e-84	304	COG0134	Indole-3-glycerol phosphate synthase	254
645478587	195	24.23	4	195	23	212	3.0e-18	85.3	COG2949	Uncharacterized periplasmic protein SanA, affects membrane permeability for vancomycin	235
645478588	346	55.62	1	344	5	346	3.0e-128	451	COG1613	ABC-type sulfate transport system, periplasmic component	348
645478592	376	58.93	2	376	1	367	0.0e+00	572	COG0505	Carbamoylphosphate synthase small subunit	368
645478597	142	55.04	14	142	1	129	1.0e-46	178	COG2852	Very-short-patch-repair endonuclease	129
645478600	352	45.01	4	348	1	351	2.0e-100	359	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
645478601	243	37.19	12	243	5	242	7.0e-49	187	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
645478603	252	48.77	11	252	6	248	2.0e-78	285	COG3338	Carbonic anhydrase	250
645478606	513	19.68	54	392	57	405	3.0e-06	47.1	COG2271	Sugar phosphate permease	448
645478610	226	50.22	1	226	1	222	2.0e-43	169	COG3235	Uncharacterized membrane protein	223
645478612	158	54.9	6	158	1	151	7.0e-39	153	COG0782	Transcription elongation factor, GreA/GreB family	151
645478614	828	47.78	15	816	1	750	0.0e+00	833	COG0058	Glucan phosphorylase	750
645478615	666	47.66	7	661	11	693	0.0e+00	725	COG1523	Pullulanase/glycogen debranching enzyme	697
645478617	351	24.57	4	296	20	292	3.0e-18	86.2	COG1566	Multidrug resistance efflux pump	352
645478621	1436	54.59	797	1418	1	627	0.0e+00	770	COG0296	1,4-alpha-glucan branching enzyme	628
645478626	593	21.06	83	590	149	699	2.0e-38	154	COG1328	Anaerobic ribonucleoside-triphosphate reductase	700
645478628	959	68.8	20	958	3	935	0.0e+00	1589	COG0178	Excinuclease UvrABC ATPase subunit	935
645478631	188	27.35	62	178	32	136	3.0e-19	88.4	COG1943	REP element-mobilizing transposase RayT	136
645478660	344	60.87	2	344	1	345	0.0e+00	494	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
645478661	356	35.03	18	351	22	348	2.0e-43	170	COG0628	Predicted PurR-regulated permease PerM	355
645478666	456	38.99	31	417	1	392	6.0e-82	298	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
645478669	222	38.74	1	222	1	218	1.0e-49	189	COG4122	Predicted O-methyltransferase YrrM	219
645478670	246	26.44	1	246	1	261	2.0e-29	122	COG1729	Periplasmic TolA-binding protein (function unknown)	262
645478671	161	68.55	1	159	2	158	1.0e-61	228	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
645478675	597	52.29	85	497	1	409	2.0e-128	452	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
645478677	372	27.04	57	310	1	240	3.0e-24	106	COG2890	Methylase of polypeptide chain release factors	280
645478678	227	36.17	1	226	3	234	2.0e-51	195	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
645478679	419	56.12	4	419	1	417	0.0e+00	568	COG0014	Gamma-glutamyl phosphate reductase	417
645478685	162	36.84	48	141	1	95	5.0e-10	57.4	COG3335	Transposase	132
645478689	385	40.27	18	379	2	370	3.0e-92	332	COG1565	SAM-dependent methyltransferase, MidA family	370
645478691	151	41.72	1	151	1	146	6.0e-36	143	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
645478692	317	54.31	3	312	2	313	1.0e-116	413	COG0275	16S rRNA C1402 N4-methylase RsmH	314
645478693	87	26.19	1	83	20	103	9.0e-09	51.8	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
645478694	582	38.77	17	571	6	599	3.0e-124	439	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
645478695	492	47.23	26	491	13	475	0.0e+00	487	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
645478699	455	48.75	16	452	16	451	5.0e-127	448	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
645478701	360	39.88	26	360	6	316	8.0e-59	220	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
645478702	430	56.38	1	430	1	416	0.0e+00	624	COG3977	Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase	417
645478703	739	22.24	1	739	3	768	1.0e-34	141	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
645478706	254	46.85	1	254	2	255	4.0e-82	297	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
645478707	319	25.45	34	303	38	308	7.0e-25	108	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
645478708	655	38.77	385	654	53	328	1.0e-36	148	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
645478709	492	64.58	1	476	18	495	0.0e+00	742	COG0753	Catalase	496
645478710	146	47.97	1	146	1	130	4.0e-33	133	COG1970	Large-conductance mechanosensitive channel	130
645478711	262	62.84	1	261	1	259	5.0e-106	377	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
645478712	479	22.45	23	369	10	391	3.0e-18	86.8	COG2814	Predicted arabinose efflux permease, MFS family	394
645478716	519	48.16	1	242	6	249	4.0e-69	255	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
645478717	312	32.67	5	301	1	296	1.0e-36	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
645478719	249	43.43	2	249	1	250	4.0e-63	234	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
645478720	193	34.54	1	193	2	168	1.0e-33	136	COG0723	Rieske Fe-S protein	177
645478721	449	50.63	7	404	2	372	8.0e-92	331	COG1290	Cytochrome b subunit of the bc complex	381
645478722	266	37.07	11	266	7	250	4.0e-61	228	COG2857	Cytochrome c1	250
645478723	265	33.8	2	216	66	278	2.0e-36	145	COG4253	Uncharacterized conserved protein, DUF2345 family	278
645478730	187	42.67	36	180	20	169	2.0e-27	115	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
645478731	236	42.6	5	227	1	217	7.0e-43	167	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
645478732	166	41.18	13	165	3	154	2.0e-33	135	COG1522	DNA-binding transcriptional regulator, Lrp family	154
645478735	256	28.02	1	253	1	253	1.0e-14	73.9	COG0730	Uncharacterized membrane protein YfcA	258
645478743	264	28.36	2	264	1	264	5.0e-40	157	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
645478744	288	49.3	1	286	1	280	9.0e-92	330	COG1091	dTDP-4-dehydrorhamnose reductase	281
645478746	198	32.79	9	189	4	179	4.0e-26	111	COG1704	Uncharacterized conserved protein	185
645478750	286	34.63	6	285	4	246	9.0e-70	257	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
645478752	531	76.65	1	531	212	742	0.0e+00	910	COG2838	Monomeric isocitrate dehydrogenase	744
645478755	405	43.49	1	405	1	447	8.0e-117	413	COG0527	Aspartokinase	447
645478757	292	39.64	7	281	4	274	2.0e-41	162	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
645478758	179	62.29	1	175	1	173	1.0e-65	242	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
645478759	291	59.52	1	289	1	286	2.0e-120	425	COG1209	dTDP-glucose pyrophosphorylase	286
645478761	354	68.36	2	354	1	339	0.0e+00	600	COG1088	dTDP-D-glucose 4,6-dehydratase	340
645478764	376	35.27	38	313	1	292	2.0e-39	156	COG0790	TPR repeat	292
645478765	384	38.17	136	381	19	280	2.0e-37	150	COG0790	TPR repeat	292
645478767	162	33.06	2	125	10	130	3.0e-22	98	COG2346	Truncated hemoglobin YjbI	133
645478774	263	42.47	1	256	1	259	3.0e-52	198	COG2116	Formate/nitrite transporter FocA, FNT family	265
645478776	163	45.75	9	160	1	151	6.0e-35	140	COG0782	Transcription elongation factor, GreA/GreB family	151
645478779	168	25	4	166	1	164	2.0e-17	81.8	COG1286	Uncharacterized membrane protein, required for colicin V production	182
645478786	163	38.1	15	140	18	141	4.0e-33	134	COG4815	Uncharacterized protein	145
645478788	242	66.67	1	240	2	240	5.0e-114	403	COG1126	ABC-type polar amino acid transport system, ATPase component	240
645478790	259	52.38	5	254	3	254	1.0e-83	303	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
645478791	450	26.68	37	447	32	412	2.0e-60	226	COG0232	dGTP triphosphohydrolase	412
645478794	380	37.53	1	378	5	362	1.0e-75	276	COG0687	Spermidine/putrescine-binding periplasmic protein	363
645478795	159	60.92	73	159	1	87	7.0e-18	83.4	COG0268	Ribosomal protein S20	88
645478796	406	37.57	69	404	1	317	1.0e-93	336	COG2829	Outer membrane phospholipase A	317
645478797	230	52.4	14	220	1	206	2.0e-64	238	COG2928	Uncharacterized membrane protein	222
645478800	602	64.55	1	595	1	585	0.0e+00	931	COG0173	Aspartyl-tRNA synthetase	585
645478806	375	31.22	1	375	2	342	4.0e-73	268	COG3317	Uncharacterized lipoprotein	342
645478807	293	50.51	1	293	4	298	3.0e-95	341	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
645478808	463	43.65	11	452	2	440	4.0e-96	345	COG2233	Xanthine/uracil permease	451
645478809	188	48.17	25	186	1	156	1.0e-50	192	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
645478810	187	41.27	1	187	3	191	5.0e-46	177	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
645478811	356	53.33	1	356	2	345	2.0e-127	449	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
645478812	153	32.68	1	150	1	153	2.0e-27	114	COG2731	Beta-galactosidase, beta subunit	154
645478814	213	55.92	1	211	1	190	2.0e-78	285	COG0066	3-isopropylmalate dehydratase small subunit	191
645478815	121	39.67	1	119	6	124	9.0e-22	95.7	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
645478817	469	56.26	2	469	1	423	0.0e+00	635	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
645478820	924	53.82	11	897	3	804	0.0e+00	1000	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
645478821	239	29.52	4	228	3	222	5.0e-27	114	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
645478822	214	52.31	1	214	2	204	1.0e-75	276	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
645478823	721	44.84	3	717	2	709	0.0e+00	696	COG2217	Cation transport ATPase	713
645478824	69	47.06	1	68	1	68	6.0e-13	65.8	COG2608	Copper chaperone CopZ	71
645478825	130	34.68	2	124	1	124	5.0e-20	90.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
645478828	288	55.78	1	277	1	294	3.0e-86	311	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
645478829	513	33.97	1	512	1	515	7.0e-104	371	COG0815	Apolipoprotein N-acyltransferase	518
645478830	287	39.5	10	284	62	335	2.0e-66	245	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
645478832	336	44	13	334	1	320	2.0e-103	369	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
645478833	92	38.64	2	89	1	75	1.0e-18	84.5	COG0254	Ribosomal protein L31	75
645478837	118	33.33	18	118	15	116	3.0e-08	50.4	COG3335	Transposase	132
645478842	298	51.61	26	298	2	271	9.0e-87	313	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
645478844	371	30.89	1	368	2	334	1.0e-90	327	COG0136	Aspartate-semialdehyde dehydrogenase	334
645478846	372	25.44	205	372	11	174	5.0e-12	65.8	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
645478847	805	22.96	33	805	65	835	9.0e-91	328	COG3188	Outer membrane usher protein FimD/PapC	835
645478848	241	24.41	1	207	5	204	6.0e-25	107	COG3121	P pilus assembly protein, chaperone PapD	235
645478857	349	67.91	3	346	1	349	0.0e+00	580	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
645478861	185	64.29	1	182	1	182	2.0e-83	301	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
645478864	558	68.11	5	558	1	554	0.0e+00	898	COG2759	Formyltetrahydrofolate synthetase	554
645478865	143	51.43	3	142	1	140	2.0e-37	148	COG2510	Uncharacterized membrane protein	140
645478866	466	49.12	169	451	1	262	1.0e-78	287	COG1760	L-serine deaminase	262
645478868	230	35.71	7	229	4	223	1.0e-42	166	COG1451	Predicted metal-dependent hydrolase	223
645478869	244	30.47	6	233	1	228	8.0e-31	127	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
645478870	192	45.76	1	177	5	176	8.0e-52	196	COG0241	Histidinol phosphatase or a related phosphatase	181
645478872	423	37.53	11	418	4	415	7.0e-64	238	COG0814	Amino acid permease	415
645478873	224	39.18	8	198	7	200	1.0e-49	189	COG0288	Carbonic anhydrase	207
645478874	512	26.55	3	507	19	532	2.0e-60	227	COG0659	Sulfate permease or related transporter, MFS superfamily	554
645478878	355	23.68	5	349	5	346	3.0e-20	93.2	COG3515	Predicted component of the type VI protein secretion system	346
645478879	172	55.95	6	172	2	169	6.0e-53	200	COG3516	Predicted component of the type VI protein secretion system	169
645478880	499	62.05	1	498	1	495	0.0e+00	782	COG3517	Predicted component of the type VI protein secretion system	495
645478881	160	24.36	1	148	1	153	5.0e-19	87.3	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
645478882	271	26.87	3	270	17	268	2.0e-28	119	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion	273
645478883	170	33.12	6	161	5	151	1.0e-19	89.2	COG3518	Predicted component of the type VI protein secretion system	157
645478884	658	31.98	1	658	1	621	1.0e-121	430	COG3519	Type VI protein secretion system component VasA	621
645478885	346	34.69	29	344	15	330	1.0e-68	254	COG3520	Predicted component of the type VI protein secretion system	335
645478886	883	40.21	12	872	1	784	0.0e+00	799	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
645478887	208	25.48	12	168	11	157	1.0e-23	103	COG3521	Predicted component of the type VI protein secretion system	159
645478888	447	40.94	1	445	1	446	4.0e-113	401	COG3522	Predicted component of the type VI protein secretion system	446
645478889	421	32.13	16	235	39	258	2.0e-43	170	COG3455	Type VI protein secretion system component VasF	262
645478890	1185	26.12	4	1184	5	1183	0.0e+00	621	COG3523	Type VI protein secretion system component VasK	1188
645478891	780	37.25	21	564	6	548	0.0e+00	472	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
645478896	197	47.45	1	195	2	191	1.0e-62	232	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
645478898	417	49.16	1	415	1	413	1.0e-124	440	COG0373	Glutamyl-tRNA reductase	414
645478903	315	61.32	1	284	2	287	1.0e-99	356	COG4607	ABC-type enterochelin transport system, periplasmic component	320
645478905	151	25.37	1	133	5	137	1.0e-10	59.2	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
645478910	227	69.16	1	227	2	228	7.0e-106	376	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
645478912	513	50.32	6	312	1	297	9.0e-111	394	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
645478917	508	41.18	52	452	7	395	7.0e-80	291	COG0029	Aspartate oxidase	518
645478918	417	43.97	17	410	23	416	2.0e-112	399	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
645478921	483	38.82	10	482	9	461	7.0e-57	215	COG0471	Di- and tricarboxylate transporter	461
645478922	293	37.32	7	289	3	279	2.0e-66	246	COG0287	Prephenate dehydrogenase	279
645478925	368	27.92	8	355	3	334	1.0e-49	190	COG0859	ADP-heptose:LPS heptosyltransferase	334
645478928	178	33.7	1	175	18	200	4.0e-17	81	COG0625	Glutathione S-transferase	211
645478930	237	39.82	3	224	5	227	4.0e-43	168	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
645478931	526	66.92	4	526	2	515	0.0e+00	789	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
645478934	408	26.28	6	407	21	421	6.0e-41	162	COG0038	H+/Cl- antiporter ClcA	443
645478936	287	25.56	18	283	31	286	9.0e-14	71.1	COG5006	Threonine/homoserine efflux transporter RhtA	292
645478937	257	31.63	18	212	3	192	1.0e-31	130	COG0518	GMP synthase - Glutamine amidotransferase domain	198
645478938	79	50	2	79	24	98	3.0e-24	103	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
645478939	334	45.82	1	320	2	321	4.0e-93	335	COG0042	tRNA-dihydrouridine synthase	323
645478940	224	33.85	11	197	17	203	3.0e-14	72.3	COG1994	Zn-dependent protease (includes SpoIVFB)	230
645478944	332	35.76	24	321	7	284	2.0e-52	199	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
645478946	114	56.25	1	78	20	98	2.0e-15	74.2	COG5416	Uncharacterized integral membrane protein	98
645478947	389	41.71	8	389	2	387	0.0e+00	469	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
645478953	303	51.33	1	298	1	299	2.0e-99	355	COG4973	Site-specific recombinase XerC	299
645478954	142	27.69	13	140	5	132	2.0e-14	71.8	COG0824	Acyl-CoA thioesterase FadM	137
645478956	354	47.27	1	329	1	286	1.0e-99	356	COG0191	Fructose/tagatose bisphosphate aldolase	286
645478960	426	60.25	21	420	1	396	5.0e-128	451	COG0786	Na+/glutamate symporter	404
645478962	256	41.02	3	256	2	256	1.0e-57	216	COG1192	Cellulose biosynthesis protein BcsQ	259
645478967	332	54.52	1	327	1	328	1.0e-109	389	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
645478969	1068	40.07	1	1057	1	1069	0.0e+00	886	COG1330	Exonuclease V gamma subunit	1078
645478970	301	40.91	6	284	1	286	3.0e-78	285	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
645478973	217	19.39	4	195	9	191	4.0e-06	44.8	COG1335	Nicotinamidase-related amidase	205
645478975	530	35.46	1	529	4	518	1.0e-118	420	COG1620	L-lactate permease	522
645478977	357	30.89	86	341	1	247	3.0e-37	149	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
645478978	263	38.24	18	220	9	212	3.0e-34	138	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
645478979	418	39.95	6	407	28	415	2.0e-117	416	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
645478983	87	45	4	63	1	60	4.0e-14	69.6	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
645478988	208	28.36	3	201	2	194	5.0e-24	104	COG3145	Alkylated DNA repair dioxygenase AlkB	194
645478989	277	35.15	116	270	2	166	1.0e-32	133	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
645478990	191	36.84	77	170	1	95	3.0e-10	58.5	COG3335	Transposase	132
645478995	484	45.72	42	484	5	448	6.0e-123	434	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
645479000	291	62.07	1	290	1	289	1.0e-102	366	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
645479004	303	21.99	6	292	1	286	9.0e-06	44.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
645479005	869	51.03	4	865	2	861	0.0e+00	1108	COG1048	Aconitase A	861
645479006	389	66.75	1	389	1	378	0.0e+00	537	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
645479016	395	21.69	2	247	3	285	3.0e-09	56.6	COG4128	Zona occludens toxin, predicted ATPase	398
645479024	397	38.38	20	374	21	363	5.0e-69	255	COG2946	DNA relaxase NicK	377
645479029	636	43.89	1	533	1	530	0.0e+00	537	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
645479047	101	49.38	21	101	1	80	3.0e-23	99	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
645479050	162	47.59	3	160	1	166	3.0e-43	167	COG0262	Dihydrofolate reductase	167
645479054	103	71.84	1	103	1	103	6.0e-38	148	COG0051	Ribosomal protein S10	104
645479056	91	51.14	1	88	1	88	1.0e-33	134	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
645479058	261	39.24	19	250	69	289	7.0e-53	200	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
645479059	252	43.65	53	230	12	192	2.0e-43	169	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
645479063	222	35.16	1	216	2	220	2.0e-42	165	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
645479065	264	27.16	124	264	39	200	2.0e-13	69.7	COG1573	Uracil-DNA glycosylase	202
645479066	147	30.3	1	147	12	176	9.0e-22	96.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
645479067	225	35.45	9	216	3	220	2.0e-32	132	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
645479069	188	28.8	3	179	1	175	2.0e-28	118	COG0431	NAD(P)H-dependent FMN reductase	184
645479077	234	38.6	5	231	1	217	1.0e-43	170	COG0850	Septum formation inhibitor MinC	219
645479078	271	70.48	1	271	1	269	5.0e-125	440	COG2894	Septum formation inhibitor-activating ATPase MinD	272
645479079	88	50	1	86	4	88	1.0e-20	91.4	COG0851	Septum formation topological specificity factor MinE	88
645479080	306	29.97	1	294	1	288	2.0e-34	139	COG0583	DNA-binding transcriptional regulator, LysR family	297
645479082	498	39.18	38	495	2	454	4.0e-116	412	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
645479085	457	56.64	1	457	1	444	0.0e+00	523	COG2056	Predicted histidine transporter YuiF, NhaC family	444
645479086	75	43.84	3	75	2	72	1.0e-07	48.4	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
645479087	181	49.44	1	178	5	181	5.0e-41	160	COG3803	Uncharacterized conserved protein, DUF924 family	182
645479089	162	25	21	162	3	154	3.0e-14	71.8	COG1225	Peroxiredoxin	157
645479090	128	36.64	1	128	8	137	1.0e-23	101	COG0824	Acyl-CoA thioesterase FadM	137
645479093	385	48.28	5	380	2	379	1.0e-122	433	COG0763	Lipid A disaccharide synthetase	381
645479095	162	35.79	48	141	1	95	3.0e-09	55	COG3335	Transposase	132
645479099	1071	69.95	13	408	1	393	0.0e+00	590	COG0458	Carbamoylphosphate synthase large subunit	400
645479100	222	27.33	4	151	7	178	1.0e-21	96.9	COG1704	Uncharacterized conserved protein	185
645479106	674	61.78	1	638	1	624	0.0e+00	666	COG1297	Uncharacterized membrane protein, oligopeptide transporter (OPT) family	624
645479116	373	24.9	18	254	15	257	3.0e-22	99.7	COG1604	CRISPR/Cas system CMR subunit Cmr6, Cas7 group, RAMP superfamily	257
645479117	124	31.86	5	113	4	116	2.0e-09	54.7	COG3337	CRISPR/Cas system CMR-associated protein Cmr5, small subunit	134
645479118	301	30.64	4	291	3	292	5.0e-47	181	COG1336	CRISPR/Cas system CMR subunit Cmr4, Cas7 group, RAMP superfamily	298
645479119	387	21.68	12	348	11	304	1.0e-15	77.7	COG1769	CRISPR/Cas system CMR-associated protein Cmr3, group 5 of RAMP superfamily	335
645479121	379	21.51	18	353	7	334	5.0e-27	115	COG1367	CRISPR/Cas system CMR-associated protein Cmr1, group 7 of RAMP superfamily	393
645479125	154	55.84	1	154	1	154	6.0e-55	206	COG2954	CYTH domain, found in class IV adenylate cyclase and various triphosphatases	156
645479126	141	49.32	1	141	7	149	3.0e-35	140	COG1981	Uncharacterized membrane protein	149
645479130	454	53.51	3	454	2	454	0.0e+00	546	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
645479131	316	40	6	316	3	320	8.0e-80	290	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
645479132	60	61.4	1	57	1	57	7.0e-16	75.8	COG3205	Uncharacterized membrane protein	72
645479139	636	64.54	6	630	1	621	0.0e+00	985	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
645479147	282	35.82	18	276	1	258	3.0e-55	208	COG0171	NH3-dependent NAD+ synthetase	268
645479151	591	48.3	9	591	3	587	0.0e+00	591	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
645479152	347	22.11	58	337	12	288	9.0e-06	44.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
645479169	191	30.05	9	188	51	230	1.0e-29	122	COG3039	Transposase and inactivated derivatives, IS5 family	230
