gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
646812183	437	42.56	4	431	2	408	1.0e-109	390	COG0593	Chromosomal replication initiation ATPase DnaA	408
646812184	356	28.65	1	352	1	362	3.0e-46	179	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
646812185	772	57.09	1	576	2	584	0.0e+00	813	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
646812186	110	34	8	107	12	111	2.0e-16	77.2	COG4679	Phage-related protein	116
646812188	167	29.17	1	156	51	216	3.0e-22	97.8	COG1451	Predicted metal-dependent hydrolase	223
646812190	337	25.85	3	333	4	345	2.0e-39	156	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
646812191	170	22.36	11	168	11	165	2.0e-10	58.7	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
646812192	441	32.95	15	441	7	442	1.0e-70	260	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
646812193	483	43.88	7	478	1	469	0.0e+00	494	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646812194	394	34.07	43	394	13	370	4.0e-60	225	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
646812195	298	29.59	1	294	2	292	1.0e-60	227	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
646812196	257	28.69	6	247	1	244	5.0e-44	171	COG1414	DNA-binding transcriptional regulator, IclR family	246
646812197	210	24.88	7	208	3	206	3.0e-19	88.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646812198	269	33.33	167	264	21	119	9.0e-18	84.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646812199	315	44.09	4	313	8	318	3.0e-82	298	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
646812201	342	24.44	6	316	4	295	3.0e-30	126	COG0492	Thioredoxin reductase	305
646812202	125	35.71	1	124	11	136	7.0e-31	125	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
646812205	321	27.4	25	313	5	291	5.0e-12	65.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
646812206	138	41.3	3	138	19	156	1.0e-23	102	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
646812207	256	44.09	12	104	8	100	1.0e-24	106	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
646812210	154	23.4	7	142	1	120	2.0e-07	48.7	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
646812211	415	53.35	10	403	2	404	0.0e+00	488	COG1219	ATP-dependent protease Clp, ATPase subunit	408
646812214	520	39.16	14	515	29	546	2.0e-126	446	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
646812216	549	39.5	3	533	7	558	6.0e-121	428	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
646812217	369	21.25	19	359	1	298	2.0e-29	123	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
646812218	807	43.99	489	801	1	314	5.0e-101	362	COG1740	Ni,Fe-hydrogenase I small subunit	355
646812219	554	46.4	1	553	1	545	0.0e+00	588	COG0374	Ni,Fe-hydrogenase I large subunit	545
646812220	282	25.86	8	267	9	265	1.0e-43	169	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
646812222	225	38.32	11	223	8	221	3.0e-44	171	COG4149	ABC-type molybdate transport system, permease component	225
646812223	235	30.83	5	234	16	253	4.0e-24	105	COG0725	ABC-type molybdate transport system, periplasmic component	258
646812225	230	39.11	5	229	1	225	4.0e-56	211	COG4149	ABC-type molybdate transport system, permease component	225
646812227	248	29.03	4	248	16	257	3.0e-35	142	COG0725	ABC-type molybdate transport system, periplasmic component	258
646812229	513	31.94	37	507	4	451	7.0e-86	311	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
646812230	488	36.38	23	484	1	450	6.0e-99	355	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
646812232	304	64.46	4	290	1	274	4.0e-112	398	COG1348	Nitrogenase subunit NifH, an ATPase	278
646812233	215	24.07	2	211	1	216	1.0e-28	119	COG0569	Trk K+ transport system, NAD-binding component	225
646812234	442	27.93	35	439	79	499	2.0e-50	193	COG0168	Trk-type K+ transport system, membrane component	499
646812235	229	37.5	5	224	3	225	4.0e-51	194	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646812237	483	25.19	101	471	8	408	2.0e-27	117	COG0840	Methyl-accepting chemotaxis protein	408
646812238	415	29.15	1	410	1	444	6.0e-73	268	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
646812239	98	24.44	1	90	4	90	6.0e-09	52.7	COG0633	Ferredoxin	102
646812243	171	29.41	1	168	1	150	3.0e-13	68.5	COG0716	Flavodoxin	151
646812249	173	21.74	1	146	2	157	3.0e-09	55.2	COG2077	Peroxiredoxin	158
646812251	431	25.53	11	421	29	436	2.0e-45	177	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
646812254	340	26.95	9	333	16	349	5.0e-27	115	COG0628	Predicted PurR-regulated permease PerM	355
646812256	446	32.06	15	446	14	450	1.0e-71	263	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
646812257	128	26.72	2	109	3	116	3.0e-09	54.1	COG1433	Predicted Fe-Mo cluster-binding protein, NifX family	121
646812259	118	26.36	1	104	1	106	1.0e-05	42.2	COG1433	Predicted Fe-Mo cluster-binding protein, NifX family	121
646812260	412	38.83	7	400	5	388	2.0e-98	353	COG0426	Flavorubredoxin	388
646812262	119	27.83	4	116	3	117	9.0e-09	52.4	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
646812265	371	37.97	1	365	2	375	5.0e-84	304	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
646812270	300	33.33	9	277	8	273	2.0e-44	173	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
646812271	442	46.55	1	442	1	437	0.0e+00	510	COG0015	Adenylosuccinate lyase	438
646812272	794	37.17	39	794	1	654	0.0e+00	580	COG0209	Ribonucleotide reductase alpha subunit	696
646812273	339	38.22	3	339	1	346	2.0e-87	316	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
646812276	149	29.77	1	128	5	135	3.0e-24	104	COG0824	Acyl-CoA thioesterase FadM	137
646812277	204	23.3	6	204	2	207	2.0e-20	92.6	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646812279	294	37.76	16	113	24	120	1.0e-19	90.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646812280	126	26.95	5	123	1	136	3.0e-08	51	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
646812284	147	46.15	1	143	3	137	2.0e-33	135	COG0394	Protein-tyrosine-phosphatase	139
646812285	238	27.78	1	231	3	254	5.0e-27	114	COG0388	Predicted amidohydrolase	274
646812286	466	28.78	1	454	4	457	1.0e-73	270	COG1109	Phosphomannomutase	464
646812287	209	37.98	3	209	2	208	5.0e-33	134	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646812288	221	23.48	1	221	1	227	6.0e-22	97.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646812289	616	31.16	404	613	2	214	2.0e-36	148	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
646812290	410	51.46	1	410	5	416	0.0e+00	542	COG0014	Gamma-glutamyl phosphate reductase	417
646812291	645	30.66	392	601	25	214	1.0e-42	168	COG2114	Adenylate cyclase, class 3	227
646812292	324	29.31	1	324	1	326	1.0e-57	217	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646812294	114	49.48	16	112	11	107	2.0e-28	117	COG1733	DNA-binding transcriptional regulator, HxlR family	120
646812295	230	41.95	32	221	35	236	6.0e-35	141	COG0390	ABC-type iron transport system FetAB, permease component	256
646812296	296	41.12	1	294	1	321	2.0e-79	289	COG0240	Glycerol-3-phosphate dehydrogenase	329
646812297	144	28.21	21	136	8	124	4.0e-10	57.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
646812298	472	57.83	2	472	6	481	0.0e+00	667	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
646812300	943	27.57	12	524	1	456	8.0e-72	265	COG0277	FAD/FMN-containing dehydrogenase	459
646812302	453	50.11	1	449	6	440	6.0e-119	421	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
646812303	202	38.82	2	171	4	172	1.0e-38	153	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
646812304	357	45.17	5	354	10	359	7.0e-116	410	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
646812305	213	27.31	1	212	1	226	5.0e-32	131	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646812307	195	26.27	1	195	1	216	8.0e-19	86.9	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
646812308	454	44.19	28	448	32	459	6.0e-123	434	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
646812311	144	40.97	4	144	9	152	2.0e-34	138	COG2131	Deoxycytidylate deaminase	164
646812312	150	40.14	6	149	1	140	7.0e-23	100	COG0511	Biotin carboxyl carrier protein	140
646812313	450	59.01	3	444	1	444	0.0e+00	589	COG0439	Biotin carboxylase	449
646812314	488	39.92	1	470	29	509	5.0e-116	411	COG0513	Superfamily II DNA and RNA helicase	513
646812317	305	26.89	1	299	3	307	1.0e-20	93.8	COG0679	Predicted permease	311
646812318	593	29.29	1	547	1	497	4.0e-90	326	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
646812321	246	36.64	1	219	3	234	1.0e-44	173	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
646812322	529	39.7	1	507	6	538	2.0e-130	460	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
646812324	309	37.22	1	309	1	314	1.0e-71	263	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
646812325	472	24.95	8	467	3	436	2.0e-43	170	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
646812326	173	45.45	1	142	5	147	9.0e-34	136	COG1981	Uncharacterized membrane protein	149
646812327	393	41.49	3	392	13	429	5.0e-127	448	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
646812328	266	35.16	13	260	4	245	1.0e-53	203	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
646812329	319	53.96	3	203	1	202	1.0e-62	233	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
646812330	644	42.47	93	642	6	555	0.0e+00	564	COG0595	mRNA degradation ribonuclease J1/J2	555
646812331	270	32.82	3	256	1	251	8.0e-52	197	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
646812332	253	66.01	5	253	3	255	1.0e-106	379	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
646812334	178	20.22	18	174	51	232	8.0e-07	46.9	COG0775	Nucleoside phosphorylase	234
646812335	355	43.45	1	353	1	346	6.0e-108	384	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
646812336	470	40	3	465	11	472	3.0e-126	445	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
646812338	726	38	3	722	1	708	0.0e+00	712	COG2217	Cation transport ATPase	713
646812339	211	32.57	3	211	12	228	7.0e-38	150	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646812340	357	27.31	132	357	91	327	6.0e-24	105	COG0642	Signal transduction histidine kinase	336
646812342	398	13.1	20	390	44	439	6.0e-17	82.1	COG1538	Outer membrane protein TolC	457
646812343	327	20.35	7	303	18	352	1.0e-21	97.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646812344	1039	44.17	1	1029	1	1023	0.0e+00	1072	COG3696	Cu/Ag efflux pump CusA	1027
646812346	451	27.75	12	446	15	447	1.0e-48	187	COG0534	Na+-driven multidrug efflux pump	455
646812347	420	46.36	1	316	3	332	2.0e-94	339	COG0460	Homoserine dehydrogenase	333
646812348	402	39.5	10	402	4	392	4.0e-96	345	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
646812350	230	30.8	1	230	22	255	5.0e-44	170	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
646812351	271	39.49	1	270	6	274	3.0e-69	255	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
646812352	66	50	1	66	1	70	2.0e-18	84.2	COG0254	Ribosomal protein L31	75
646812353	292	32.98	1	272	3	284	8.0e-60	223	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
646812354	511	29.11	223	510	1	274	7.0e-33	135	COG0388	Predicted amidohydrolase	274
646812355	286	32.4	1	284	3	289	2.0e-38	153	COG0382	4-hydroxybenzoate polyprenyltransferase	289
646812373	366	23.39	121	350	48	281	3.0e-12	66.4	COG4974	Site-specific recombinase XerD	300
646812379	242	26.19	1	239	7	249	2.0e-39	155	COG0631	Serine/threonine protein phosphatase PrpC	262
646812380	364	40.44	5	361	3	359	5.0e-97	348	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
646812381	170	42.59	2	163	1	161	2.0e-36	145	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
646812382	441	45.77	5	435	6	442	2.0e-107	383	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
646812383	530	31.54	7	527	11	536	1.0e-111	397	COG0405	Gamma-glutamyltranspeptidase	539
646812384	268	27.51	3	267	2	252	4.0e-10	58.9	COG0730	Uncharacterized membrane protein YfcA	258
646812388	322	26.32	28	307	34	314	7.0e-36	144	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646812389	262	30.92	11	256	9	268	2.0e-32	132	COG3769	Predicted mannosyl-3-phosphoglycerate phosphatase, HAD superfamily	274
646812390	437	33.79	4	426	7	421	1.0e-87	317	COG2379	Glycerate-2-kinase	422
646812392	582	20.42	83	541	36	495	1.0e-30	128	COG0366	Glycosidase	505
646812393	283	51.44	6	282	2	275	3.0e-103	368	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
646812394	486	50.83	8	486	8	483	0.0e+00	624	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
646812395	236	31.53	9	226	2	221	1.0e-39	156	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
646812396	606	37.02	8	601	5	574	0.0e+00	594	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
646812397	207	50.74	6	207	9	210	5.0e-56	210	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
646812398	544	56.24	25	544	2	522	0.0e+00	635	COG0033	Phosphoglucomutase	524
646812399	402	33.06	40	400	70	431	1.0e-60	227	COG0166	Glucose-6-phosphate isomerase	446
646812400	317	33.96	152	310	1	158	6.0e-35	141	COG3272	Uncharacterized conserved protein YbgA, DUF1722 family	163
646812402	182	37.86	85	182	11	112	1.0e-19	89.2	COG2824	Uncharacterized Zn-ribbon-containing protein	112
646812403	389	57.92	1	381	2	385	0.0e+00	520	COG0027	Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	394
646812404	256	35.91	22	236	48	260	4.0e-39	154	COG2992	Uncharacterized FlgJ-related protein	262
646812405	245	33.96	1	241	1	266	3.0e-54	205	COG0253	Diaminopimelate epimerase	272
646812406	196	38.78	6	196	1	194	4.0e-40	157	COG0237	Dephospho-CoA kinase	201
646812407	184	23.68	3	179	54	281	9.0e-15	73.5	COG0421	Spermidine synthase	282
646812408	331	57.77	1	329	1	340	2.0e-122	432	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
646812410	258	36.88	1	256	8	266	3.0e-53	202	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
646812411	146	30.09	33	144	14	126	2.0e-13	68.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
646812412	234	31.72	16	232	18	243	2.0e-41	162	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
646812413	167	28.09	1	167	2	170	4.0e-18	84.3	COG0431	NAD(P)H-dependent FMN reductase	184
646812414	188	41.58	1	183	3	192	2.0e-42	165	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
646812416	370	36.07	1	364	7	380	4.0e-86	311	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
646812417	281	22.98	6	281	5	325	2.0e-19	89.5	COG0124	Histidyl-tRNA synthetase	429
646812418	417	52.36	3	416	2	425	0.0e+00	571	COG0104	Adenylosuccinate synthase	430
646812419	183	42.62	1	183	1	183	8.0e-38	150	COG2952	Uncharacterized protein	183
646812420	372	49.2	1	372	1	363	2.0e-130	458	COG0505	Carbamoylphosphate synthase small subunit	368
646812422	156	42.18	1	145	16	157	2.0e-21	95.4	COG1267	Phosphatidylglycerophosphatase A	160
646812424	374	47.8	213	371	1	159	2.0e-55	210	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
646812425	273	24.46	1	233	12	237	1.0e-22	100	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
646812427	449	63.79	15	440	4	430	0.0e+00	669	COG0422	Thiamine biosynthesis protein ThiC	432
646812429	371	39.07	41	314	3	265	3.0e-55	209	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
646812430	383	39.64	2	383	5	393	8.0e-100	357	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
646812431	498	24.31	185	495	85	390	1.0e-35	144	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
646812432	115	20.2	1	99	1	92	3.0e-07	46.9	COG1694	NTP pyrophosphatase, house-cleaning of non-canonical NTPs	102
646812439	227	57.14	4	107	8	111	1.0e-40	160	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
646812441	358	23.15	49	343	8	282	4.0e-25	109	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
646812442	306	41.84	4	295	1	284	3.0e-68	252	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
646812444	1157	34.38	307	1157	1	842	0.0e+00	679	COG1410	Methionine synthase I, cobalamin-binding domain	842
646812446	202	39.79	7	193	15	203	8.0e-42	163	COG3647	Uncharacterized membrane protein YjdF	205
646812447	335	26.82	1	329	13	356	4.0e-55	208	COG0174	Glutamine synthetase	443
646812448	270	27.55	169	265	22	119	1.0e-18	87.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646812449	198	20.98	1	194	1	205	2.0e-20	92.2	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646812451	243	16.43	9	210	43	233	3.0e-12	65.8	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
646812452	171	59.01	1	161	1	160	1.0e-64	239	COG1854	S-ribosylhomocysteine lyase LuxS, autoinducer biosynthesis	161
646812456	408	23.73	9	378	14	358	3.0e-17	83.5	COG3864	Predicted metal-dependent peptidase	396
646812459	133	29.66	14	125	11	126	1.0e-08	52.3	COG2703	Hemerythrin	144
646812460	230	50.22	1	228	2	228	7.0e-73	267	COG1489	DNA-binding protein, stimulates sugar fermentation	235
646812461	354	25.67	20	354	13	347	2.0e-36	146	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
646812462	215	28.04	1	213	1	207	7.0e-38	150	COG0288	Carbonic anhydrase	207
646812464	226	27.95	9	226	3	229	1.0e-28	120	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646812465	505	51.79	1	504	3	495	0.0e+00	517	COG3333	TctA family transporter	504
646812467	323	33.65	10	323	6	318	9.0e-63	234	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
646812469	318	34.87	18	314	9	294	3.0e-65	242	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
646812470	409	34.96	10	376	2	357	1.0e-78	286	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
646812471	137	39.29	38	120	10	91	3.0e-18	84.3	COG1144	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit	91
646812472	187	30.26	1	187	3	193	1.0e-26	112	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
646812473	218	31.48	1	211	3	216	6.0e-33	134	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
646812474	505	29.34	17	503	37	554	4.0e-79	289	COG0747	ABC-type transport system, periplasmic component	556
646812475	129	48.06	1	129	3	130	3.0e-37	147	COG0103	Ribosomal protein S9	130
646812476	139	52.59	4	137	3	137	3.0e-45	173	COG0102	Ribosomal protein L13	148
646812478	224	31.42	6	224	3	226	2.0e-43	168	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646812480	223	22.12	1	217	8	219	1.0e-11	63.6	COG0704	Phosphate uptake regulator	240
646812481	576	27.8	12	247	17	251	4.0e-40	159	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
646812482	355	59.5	1	354	4	361	0.0e+00	511	COG0216	Protein chain release factor A	363
646812483	86	43.02	1	86	1	86	6.0e-09	52.6	COG0268	Ribosomal protein S20	88
646812484	444	45	1	444	7	461	2.0e-107	383	COG1109	Phosphomannomutase	464
646812485	153	30.46	11	152	16	165	5.0e-18	83.7	COG0597	Lipoprotein signal peptidase	167
646812486	422	46.1	1	422	1	422	0.0e+00	546	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
646812487	192	25.13	7	191	4	191	9.0e-29	120	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
646812488	119	61.02	1	118	1	118	8.0e-37	145	COG0292	Ribosomal protein L20	118
646812489	65	49.23	1	65	1	65	1.0e-08	51.8	COG0291	Ribosomal protein L35	65
646812490	175	54.29	1	175	1	175	3.0e-55	207	COG0290	Translation initiation factor IF-3	176
646812491	602	51.13	26	601	15	584	0.0e+00	665	COG0441	Threonyl-tRNA synthetase	589
646812494	252	27.8	16	248	21	261	1.0e-22	100	COG0575	CDP-diglyceride synthetase	265
646812495	355	41.82	1	352	4	375	1.0e-107	383	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
646812498	185	29.82	1	167	1	165	2.0e-22	98.4	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
646812499	329	41.87	1	325	2	331	1.0e-97	349	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
646812501	461	31.46	220	461	22	280	1.0e-44	174	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
646812502	103	40.38	1	103	1	104	2.0e-22	96.8	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
646812503	259	60.62	1	259	4	261	7.0e-101	360	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
646812505	227	27.15	6	225	13	233	7.0e-32	130	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
646812506	275	36.27	174	274	21	122	5.0e-22	98.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646812514	311	29.85	35	295	4	265	6.0e-32	131	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646812515	317	41.37	9	307	1	304	2.0e-63	236	COG0010	Arginase family enzyme	305
646812516	216	42.23	9	213	13	218	6.0e-49	187	COG0765	ABC-type amino acid transport system, permease component	222
646812517	219	39.51	8	211	13	217	9.0e-42	163	COG0765	ABC-type amino acid transport system, permease component	222
646812518	265	58.06	9	256	3	238	1.0e-97	349	COG1126	ABC-type polar amino acid transport system, ATPase component	240
646812519	292	20	1	290	1	291	1.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
646812520	623	29.77	404	613	2	214	3.0e-36	146	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
646812522	208	23.79	1	202	1	203	3.0e-20	91.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646812524	401	53.96	5	395	1	383	0.0e+00	478	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
646812525	341	57.65	41	321	6	286	3.0e-96	345	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
646812526	322	24.77	1	322	4	301	2.0e-38	153	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
646812528	258	28.98	11	253	1	244	5.0e-44	171	COG1414	DNA-binding transcriptional regulator, IclR family	246
646812529	323	41.45	14	315	10	312	8.0e-76	277	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
646812531	499	40.95	1	499	1	500	1.0e-124	439	COG3333	TctA family transporter	504
646812532	211	33.68	1	189	6	193	4.0e-35	141	COG0684	Regulator of RNase E activity RraA	210
646812533	427	21.76	16	426	5	404	9.0e-36	145	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
646812534	89	28.89	1	89	3	92	8.0e-15	72.2	COG1254	Acylphosphatase	92
646812535	241	26.94	1	220	4	237	5.0e-21	94.8	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
646812536	224	22.31	4	216	9	249	2.0e-11	63.1	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
646812537	176	29.44	1	169	4	182	4.0e-29	121	COG3709	Ribose 1,5-bisphosphokinase PhnN	192
646812538	212	28.21	31	183	42	190	5.0e-22	98	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
646812539	381	31.81	10	373	9	377	8.0e-82	297	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
646812540	234	44.2	4	227	5	227	3.0e-68	251	COG4778	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL	235
646812541	278	48.33	39	278	20	256	2.0e-68	252	COG4107	ABC-type phosphonate transport system, ATPase component	258
646812542	275	54.31	3	268	14	279	1.0e-91	329	COG3627	Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase	291
646812543	349	33.14	3	337	2	345	4.0e-68	251	COG3626	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI	367
646812544	178	24.29	14	176	21	195	3.0e-12	64.9	COG3625	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH	196
646812546	285	38.33	1	285	16	282	2.0e-48	186	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
646812547	289	37.29	1	286	2	296	3.0e-62	231	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
646812548	252	45.2	1	249	3	252	7.0e-70	257	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
646812549	240	24.02	7	234	9	235	1.0e-36	146	COG2188	DNA-binding transcriptional regulator, GntR family	236
646812551	226	21.43	6	222	3	225	5.0e-28	118	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646812552	262	40.46	1	261	1	248	5.0e-64	237	COG3338	Carbonic anhydrase	250
646812553	637	27.89	324	631	72	408	2.0e-23	104	COG0840	Methyl-accepting chemotaxis protein	408
646812554	277	54.58	4	275	2	272	4.0e-106	377	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
646812555	398	31.55	40	398	67	430	1.0e-59	224	COG0166	Glucose-6-phosphate isomerase	446
646812556	923	28.15	179	529	30	396	5.0e-59	223	COG1061	Superfamily II DNA or RNA helicase	442
646812557	371	38.42	22	357	60	364	2.0e-72	266	COG1858	Cytochrome c peroxidase	364
646812558	301	25.93	32	300	29	271	2.0e-19	89.8	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
646812560	428	36.02	28	428	61	481	3.0e-91	328	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
646812561	451	33.41	14	415	26	405	5.0e-63	235	COG3487	Uncharacterized iron-regulated protein	446
646812563	395	14.25	12	386	44	431	3.0e-19	89.8	COG1538	Outer membrane protein TolC	457
646812564	417	24.06	13	410	2	353	1.0e-29	124	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646812565	234	52.25	7	227	1	222	8.0e-80	290	COG1136	ABC-type lipoprotein export system, ATPase component	226
646812566	403	28.95	18	403	2	419	6.0e-25	109	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
646812567	376	19.9	1	368	4	384	2.0e-41	163	COG3182	Uncharacterized iron-regulated membrane protein	442
646812568	443	36.91	1	439	2	461	2.0e-101	363	COG0415	Deoxyribodipyrimidine photolyase	461
646812569	472	20.08	1	459	1	470	1.0e-26	114	COG1233	Phytoene dehydrogenase-related protein	487
646812571	236	35.12	1	232	2	242	3.0e-36	145	COG3279	DNA-binding response regulator, LytR/AlgR family	244
646812572	177	64.15	19	177	2	160	1.0e-69	255	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
646812573	151	24.16	1	142	1	147	5.0e-13	67.1	COG4276	Ligand-binding SRPBCC domain	153
646812574	310	38.02	1	305	4	313	8.0e-85	307	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
646812575	511	29.61	13	489	34	511	1.0e-77	284	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
646812577	256	45.21	1	248	3	258	4.0e-74	271	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
646812578	856	24.7	390	781	8	408	1.0e-34	142	COG0840	Methyl-accepting chemotaxis protein	408
646812586	332	27.44	5	325	14	395	7.0e-41	161	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
646812588	102	30.77	1	102	2	105	2.0e-19	86.9	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
646812589	819	52.49	1	803	2	791	0.0e+00	966	COG1251	NAD(P)H-nitrite reductase, large subunit	793
646812590	573	23.69	16	245	18	258	7.0e-29	122	COG0631	Serine/threonine protein phosphatase PrpC	262
646812591	146	46.53	5	146	8	151	2.0e-43	167	COG1513	Cyanate lyase	151
646812592	278	32.46	1	262	3	259	9.0e-37	147	COG2116	Formate/nitrite transporter FocA, FNT family	265
646812594	227	28.89	13	227	3	226	3.0e-29	121	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646812595	664	28.46	2	662	41	765	2.0e-112	400	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
646812596	459	24.44	1	350	4	331	7.0e-49	188	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
646812597	269	29.39	2	259	5	246	5.0e-42	164	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
646812598	264	47.67	5	262	3	248	4.0e-87	314	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
646812602	432	43.19	20	399	24	406	7.0e-90	324	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
646812603	322	28.16	34	272	6	218	8.0e-22	97.9	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
646812604	81	54.32	1	81	2	81	9.0e-19	85.2	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
646812605	224	52.21	1	223	3	228	2.0e-84	305	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
646812607	229	23.08	6	223	1	229	1.0e-17	83.4	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
646812608	128	36.51	4	127	1	126	5.0e-15	73.3	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
646812609	77	39.47	1	76	1	75	2.0e-10	57.3	COG1826	Sec-independent protein translocase protein TatA	94
646812610	530	35.8	7	530	16	577	2.0e-124	439	COG0018	Arginyl-tRNA synthetase	577
646812612	108	37.74	1	104	4	109	2.0e-22	97.2	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
646812613	178	38.1	1	175	3	191	3.0e-38	151	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
646812614	332	51.04	2	332	1	333	3.0e-112	398	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
646812615	398	49.87	1	394	2	390	0.0e+00	471	COG0126	3-phosphoglycerate kinase	395
646812616	234	39.36	1	234	4	250	6.0e-57	213	COG0149	Triosephosphate isomerase	251
646812617	275	57.92	1	259	2	259	5.0e-107	380	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
646812618	402	42.93	2	376	15	394	2.0e-107	382	COG0019	Diaminopimelate decarboxylase	394
646812619	259	21.8	3	256	9	267	4.0e-36	144	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
646812620	355	42.86	91	352	5	276	1.0e-65	243	COG0077	Prephenate dehydratase	279
646812621	368	37.12	14	368	7	356	9.0e-78	284	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
646812622	600	50.16	3	600	14	619	0.0e+00	761	COG1154	Deoxyxylulose-5-phosphate synthase	627
646812624	182	23.08	1	181	4	184	3.0e-27	114	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
646812625	390	15.95	10	309	11	310	6.0e-14	72.2	COG2814	Predicted arabinose efflux permease, MFS family	394
646812626	297	22.03	1	294	6	292	2.0e-08	53.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
646812628	309	24.05	3	308	1	309	1.0e-18	87.3	COG0679	Predicted permease	311
646812629	166	38.57	27	160	58	197	2.0e-21	95.4	COG0791	Cell wall-associated hydrolase, NlpC family	197
646812631	850	48.81	1	850	9	879	0.0e+00	991	COG0013	Alanyl-tRNA synthetase	879
646812633	309	47.08	1	308	3	300	2.0e-77	282	COG0492	Thioredoxin reductase	305
646812634	468	33.19	1	468	2	456	2.0e-43	170	COG0471	Di- and tricarboxylate transporter	461
646812636	218	31	1	214	1	228	3.0e-37	148	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646812637	496	47.87	1	302	2	297	2.0e-96	346	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
646812638	241	38.72	3	236	1	228	1.0e-57	216	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
646812639	660	43.27	1	590	2	562	0.0e+00	533	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
646812640	255	17.05	17	145	13	132	1.0e-07	50.3	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
646812641	309	47.08	1	308	3	300	3.0e-77	282	COG0492	Thioredoxin reductase	305
646812642	257	45.69	1	257	2	266	2.0e-76	278	COG0289	Dihydrodipicolinate reductase	266
646812643	449	51.88	1	447	4	453	0.0e+00	581	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
646812644	333	39.87	22	332	10	300	2.0e-87	316	COG1242	Radical SAM superfamily enzyme	312
646812645	299	21.55	4	295	2	288	4.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
646812646	684	38.18	7	623	1	640	0.0e+00	472	COG0210	Superfamily I DNA or RNA helicase	655
646812648	258	33.21	1	257	2	258	4.0e-49	188	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
646812649	156	51.97	4	155	1	150	2.0e-44	171	COG0691	tmRNA-binding protein	153
646812650	488	49.08	1	488	3	482	0.0e+00	579	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
646812651	227	42.79	1	227	2	216	1.0e-71	263	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
646812652	74	21.82	9	63	6	60	1.0e-05	41.7	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
646812658	786	15.71	8	510	43	661	9.0e-28	119	COG3893	Inactivated superfamily I helicase	697
646812659	364	62.98	127	359	1	235	4.0e-94	338	COG1186	Protein chain release factor B	239
646812662	103	21.62	2	103	4	114	2.0e-13	67.5	COG1539	Dihydroneopterin aldolase	121
646812663	206	39.6	6	204	4	198	2.0e-33	136	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
646812664	329	40.12	1	329	21	322	2.0e-94	339	COG0379	Quinolinate synthase	324
646812665	273	40.22	1	272	3	277	1.0e-78	286	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
646812666	326	29.75	19	325	9	322	5.0e-44	171	COG0618	nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs	332
646812667	456	20.93	222	446	20	277	6.0e-20	92.5	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
646812668	302	47.97	1	291	2	296	4.0e-102	364	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
646812670	293	38.72	1	293	4	298	1.0e-75	276	COG0083	Homoserine kinase	299
646812672	888	54.96	384	883	2	504	0.0e+00	580	COG0532	Translation initiation factor IF-2, a GTPase	509
646812673	118	23.93	1	116	2	118	1.0e-14	71.8	COG0858	Ribosome-binding factor A	118
646812674	142	36.3	1	142	8	153	1.0e-27	115	COG0779	Ribosome maturation factor RimP	153
646812675	208	29.47	1	206	1	207	3.0e-26	111	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646812676	335	34.73	4	169	5	144	3.0e-39	156	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
646812678	187	49.62	1	131	1	131	1.0e-38	153	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
646812679	527	41.9	1	313	1	313	4.0e-85	309	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
646812680	550	37.23	10	547	1	540	5.0e-110	391	COG0539	Ribosomal protein S1	541
646812681	277	38.95	1	277	2	284	1.0e-80	293	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
646812682	426	41.73	19	424	18	424	3.0e-109	388	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
646812683	772	26.02	145	772	1	650	1.0e-83	305	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
646812684	330	48.52	1	328	10	335	2.0e-108	386	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
646812685	114	43.69	1	101	2	104	5.0e-27	112	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
646812686	312	56.01	1	310	1	316	7.0e-118	416	COG0825	Acetyl-CoA carboxylase alpha subunit	317
646812687	419	54.87	1	417	2	411	0.0e+00	463	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
646812688	76	53.95	1	76	4	79	3.0e-09	53.4	COG0236	Acyl carrier protein	80
646812689	247	45.06	1	245	1	250	4.0e-50	191	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646812690	249	23.58	2	245	4	212	1.0e-30	127	COG0602	Organic radical activating enzyme	212
646812692	223	51.12	1	221	1	220	5.0e-67	247	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
646812693	406	34.01	3	391	7	402	1.0e-96	346	COG0303	Molybdopterin biosynthesis enzyme	404
646812695	222	25	1	222	5	242	3.0e-30	125	COG1385	16S rRNA U1498 N3-methylase RsmE	246
646812696	223	26.43	5	220	2	227	3.0e-29	121	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646812699	342	22.26	79	342	17	250	3.0e-23	102	COG2857	Cytochrome c1	250
646812700	416	41.75	4	402	1	372	1.0e-77	284	COG1290	Cytochrome b subunit of the bc complex	381
646812701	168	32.95	1	163	5	177	1.0e-27	116	COG0723	Rieske Fe-S protein	177
646812702	492	26.98	1	434	1	382	1.0e-68	254	COG0498	Threonine synthase	411
646812703	299	50.94	22	283	1	265	4.0e-72	265	COG0548	Acetylglutamate kinase	265
646812704	911	21.39	5	710	19	839	5.0e-66	246	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
646812705	186	23.5	8	183	9	187	8.0e-18	83.4	COG0352	Thiamine monophosphate synthase	211
646812706	228	40.1	26	221	38	243	3.0e-36	145	COG0356	FoF1-type ATP synthase, membrane subunit a	246
646812707	401	47.37	1	338	6	347	3.0e-105	375	COG1171	Threonine dehydratase	347
646812708	759	55.49	430	757	5	330	1.0e-112	401	COG0620	Methionine synthase II (cobalamin-independent)	330
646812710	229	46.52	1	229	1	229	1.0e-77	282	COG0336	tRNA G37 N-methylase TrmD	240
646812711	118	58.12	1	117	1	115	9.0e-31	125	COG0335	Ribosomal protein L19	115
646812713	423	18.11	140	374	39	285	5.0e-14	72.4	COG1533	DNA repair photolyase	297
646812714	257	26.5	4	248	3	285	1.0e-33	136	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
646812715	248	45.41	1	215	2	219	2.0e-66	245	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
646812716	269	39.85	1	266	5	270	4.0e-36	144	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
646812717	202	38.62	14	198	13	201	5.0e-29	121	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
646812718	211	31.65	1	189	7	224	6.0e-30	124	COG0300	Short-chain dehydrogenase	265
646812719	457	34.93	1	457	1	448	5.0e-87	315	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
646812720	156	33.33	3	156	1	155	6.0e-18	83.4	COG3610	Uncharacterized membrane protein YjjB, DUF3815 family	156
646812721	255	31.84	1	242	7	250	1.0e-39	156	COG2966	Uncharacterized membrane protein YjjP, DUF1212 family	250
646812722	318	25.66	204	315	11	123	6.0e-15	74.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646812723	695	19.37	21	695	45	768	6.0e-47	182	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
646812724	326	38.64	33	325	1	292	7.0e-67	247	COG1230	Co/Zn/Cd efflux system component	296
646812725	99	27.78	8	97	7	88	8.0e-08	48.7	COG1937	DNA-binding transcriptional regulator, FrmR family	89
646812726	325	31.43	211	314	11	115	7.0e-15	74.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646812727	697	17.5	13	697	38	768	7.0e-41	162	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
646812728	594	31.23	24	576	18	561	6.0e-102	365	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
646812729	589	32.85	30	580	19	565	3.0e-95	342	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
646812731	391	17.02	15	388	26	389	1.0e-09	58.3	COG2814	Predicted arabinose efflux permease, MFS family	394
646812732	183	43.09	1	183	3	190	3.0e-24	105	COG1971	Putative Mn2+ efflux pump MntP	190
646812733	260	33.21	1	253	3	263	2.0e-35	142	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646812734	224	39.25	9	222	11	222	1.0e-52	199	COG0765	ABC-type amino acid transport system, permease component	222
646812736	207	19.52	1	203	2	251	9.0e-18	83.8	COG1521	Pantothenate kinase type III	251
646812737	202	44.13	1	202	2	213	3.0e-46	178	COG0040	ATP phosphoribosyltransferase	290
646812740	320	43.41	1	302	6	314	2.0e-87	315	COG0180	Tryptophanyl-tRNA synthetase	314
646812741	430	24.77	12	311	5	321	1.0e-30	128	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
646812745	691	23.19	6	691	18	719	7.0e-60	225	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
646812746	327	31.07	225	326	22	124	1.0e-18	87.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646812747	227	24.67	10	225	2	226	2.0e-24	105	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646812748	571	21.02	283	571	42	327	5.0e-24	106	COG0642	Signal transduction histidine kinase	336
646812752	814	34.13	5	546	4	523	6.0e-120	425	COG0370	Fe2+ transport system protein B	653
646812753	74	35.21	1	71	1	71	7.0e-13	65.6	COG1918	Fe2+ transport system protein FeoA	75
646812756	135	27.94	1	135	2	136	8.0e-21	92.6	COG0848	Biopolymer transport protein ExbD	137
646812758	437	27.55	253	433	12	207	2.0e-23	103	COG0811	Biopolymer transport protein ExbB/TolQ	216
646812760	521	15.27	1	373	5	386	4.0e-12	66.9	COG3182	Uncharacterized iron-regulated membrane protein	442
646812762	759	21.59	24	759	48	750	8.0e-43	169	COG4774	Outer membrane receptor for monomeric catechols	750
646812763	414	53.94	1	414	1	419	0.0e+00	525	COG0172	Seryl-tRNA synthetase	429
646812765	378	31.3	6	368	3	376	9.0e-66	244	COG1252	NADH dehydrogenase, FAD-containing subunit	405
646812766	368	57.92	1	366	1	366	0.0e+00	490	COG0686	Alanine dehydrogenase	371
646812767	209	29.9	7	209	3	206	2.0e-24	106	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646812768	746	28.15	371	742	4	408	1.0e-33	138	COG0840	Methyl-accepting chemotaxis protein	408
646812769	204	37.56	1	202	1	205	4.0e-23	101	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646812770	248	60.42	7	246	2	240	6.0e-114	403	COG1126	ABC-type polar amino acid transport system, ATPase component	240
646812771	359	34.95	150	355	19	219	8.0e-47	181	COG0765	ABC-type amino acid transport system, permease component	222
646812772	393	51.91	1	393	6	397	2.0e-126	445	COG4597	ABC-type amino acid transport system, permease component	397
646812773	338	31.4	1	237	2	238	5.0e-28	118	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646812774	126	23.86	3	90	8	93	9.0e-08	49.1	COG3062	Cytoplasmic chaperone NapD for the signal peptide of periplasmic nitrate reductase NapAB	94
646812777	202	27.37	1	179	2	148	6.0e-26	110	COG3043	Nitrate reductase cytochrome c-type subunit	155
646812781	298	21.81	1	295	2	315	2.0e-31	129	COG0547	Anthranilate phosphoribosyltransferase	338
646812782	185	32.8	1	185	1	189	7.0e-35	140	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
646812783	243	49.39	1	242	3	243	1.0e-81	296	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
646812785	221	19.72	9	210	4	214	2.0e-14	72.9	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
646812786	320	41.67	1	320	1	322	1.0e-92	332	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
646812788	261	34.62	3	230	31	257	9.0e-50	190	COG1119	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA	257
646812789	90	53.41	1	88	1	88	2.0e-22	96.8	COG0184	Ribosomal protein S15P/S13E	89
646812790	133	28.89	1	133	1	132	7.0e-22	96.2	COG1959	DNA-binding transcriptional regulator, IscR family	150
646812791	351	26.96	2	342	1	324	8.0e-43	167	COG2404	Oligoribonuclease NrnB or cAMP/cGMP phosphodiesterase, DHH superfamily	339
646812793	388	23.96	95	381	16	279	5.0e-24	105	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
646812794	709	30	334	638	80	408	2.0e-29	124	COG0840	Methyl-accepting chemotaxis protein	408
646812796	417	39.48	1	417	3	422	7.0e-76	277	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
646812797	133	31.01	1	122	1	129	3.0e-22	97.6	COG0394	Protein-tyrosine-phosphatase	139
646812798	319	34.85	24	319	11	316	2.0e-49	189	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
646812799	142	43.48	7	142	1	137	2.0e-38	151	COG1832	Predicted CoA-binding protein	140
646812800	441	24.53	110	421	17	327	4.0e-28	119	COG0642	Signal transduction histidine kinase	336
646812801	228	37.55	1	220	1	228	9.0e-49	187	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646812803	355	35.8	19	354	8	285	8.0e-83	300	COG0191	Fructose/tagatose bisphosphate aldolase	286
646812805	426	18.44	95	413	1	303	1.0e-08	54.6	COG0582	Integrase	309
646812825	113	35.51	1	107	1	107	2.0e-22	97.4	COG1733	DNA-binding transcriptional regulator, HxlR family	120
646812826	387	27.01	11	380	8	365	4.0e-37	149	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646812827	1043	46.07	1	1029	1	1009	0.0e+00	992	COG0841	Multidrug efflux pump subunit AcrB	1009
646812828	473	28.85	12	465	1	449	2.0e-66	246	COG1538	Outer membrane protein TolC	457
646812830	477	29.41	234	466	2	239	9.0e-43	168	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
646812831	131	30.53	2	129	9	137	9.0e-18	82.6	COG0848	Biopolymer transport protein ExbD	137
646812833	295	23.57	1	290	18	323	2.0e-43	169	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
646812834	970	23.64	718	969	93	329	2.0e-24	108	COG0642	Signal transduction histidine kinase	336
646812835	170	38.86	3	170	2	167	9.0e-31	126	COG0703	Shikimate kinase	172
646812836	430	49.88	12	430	6	423	0.0e+00	522	COG0141	Histidinol dehydrogenase	425
646812838	298	32.81	2	298	9	322	9.0e-49	187	COG0142	Geranylgeranyl pyrophosphate synthase	322
646812839	431	38.33	1	414	1	412	4.0e-94	338	COG0373	Glutamyl-tRNA reductase	414
646812840	572	40.42	1	570	1	500	0.0e+00	491	COG0442	Prolyl-tRNA synthetase	500
646812842	467	27.66	19	409	13	385	6.0e-46	178	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
646812843	409	21.44	1	409	9	458	4.0e-37	149	COG0815	Apolipoprotein N-acyltransferase	518
646812844	89	42.7	1	89	2	90	2.0e-21	93.7	COG1862	Preprotein translocase subunit YajC	97
646812845	522	42.35	1	508	2	498	2.0e-119	423	COG0342	Preprotein translocase subunit SecD	506
646812846	323	46.73	1	304	1	303	6.0e-75	274	COG0341	Preprotein translocase subunit SecF	305
646812850	821	46.88	1	819	3	814	0.0e+00	920	COG0495	Leucyl-tRNA synthetase	814
646812852	389	29.02	10	380	11	420	5.0e-66	245	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
646812854	152	33.04	5	118	12	126	9.0e-14	69.6	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
646812855	706	25.19	338	682	4	391	9.0e-44	172	COG1061	Superfamily II DNA or RNA helicase	442
646812856	542	33.25	2	385	8	389	8.0e-51	195	COG0475	Kef-type K+ transport system, membrane component KefB	397
646812859	755	29.7	446	746	76	405	3.0e-34	140	COG0840	Methyl-accepting chemotaxis protein	408
646812861	989	35.44	4	964	26	1083	0.0e+00	844	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
646812862	703	34.44	522	701	5	180	6.0e-41	162	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646812865	377	25.55	10	370	7	345	8.0e-39	154	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
646812866	151	25.66	2	104	3	113	3.0e-09	54.9	COG1433	Predicted Fe-Mo cluster-binding protein, NifX family	121
646812867	496	47.54	1	302	2	297	4.0e-96	345	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
646812869	225	36.28	3	223	2	225	2.0e-47	182	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646812870	415	25.93	137	389	39	306	2.0e-18	87.1	COG0642	Signal transduction histidine kinase	336
646812871	379	33.83	1	375	2	401	9.0e-84	304	COG2081	Predicted flavoprotein YhiN	408
646812872	269	41.98	1	262	6	267	8.0e-35	141	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
646812873	249	43.7	6	239	1	236	2.0e-67	248	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
646812874	289	33.67	1	288	8	303	5.0e-59	221	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
646812876	270	44.57	1	256	1	255	9.0e-71	260	COG1692	Calcineurin-like phosphoesterase	266
646812877	213	39.02	10	208	2	192	2.0e-43	168	COG2231	Uncharacterized protein related to Endonuclease III	215
646812880	236	34.58	1	235	7	237	4.0e-52	198	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
646812881	395	39.82	1	394	2	438	7.0e-123	433	COG1570	Exonuclease VII, large subunit	440
646812882	160	35.62	1	160	2	158	2.0e-26	111	COG0835	Chemotaxis signal transduction protein	165
646812885	175	48.43	20	174	1	156	2.0e-49	188	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
646812886	120	43.86	52	108	1	57	1.0e-10	58.8	COG3411	(2Fe-2S) ferredoxin	64
646812887	127	57.76	5	120	4	119	1.0e-40	158	COG0853	Aspartate 1-decarboxylase	126
646812888	107	38.38	8	101	3	101	1.0e-11	61.8	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
646812889	286	38.74	1	248	7	250	2.0e-49	189	COG0142	Geranylgeranyl pyrophosphate synthase	322
646812890	85	45.16	1	84	1	93	3.0e-19	86.7	COG0234	Co-chaperonin GroES (HSP10)	96
646812891	547	48.73	1	532	2	523	0.0e+00	467	COG0459	Chaperonin GroEL (HSP60 family)	524
646812892	206	26.73	27	125	13	107	3.0e-08	51.9	COG0727	Fe-S-cluster containining protein	132
646812893	599	46.2	1	599	1	597	0.0e+00	698	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
646812894	405	43.63	4	405	2	387	1.0e-120	426	COG0192	S-adenosylmethionine synthetase	388
646812895	289	58.16	1	282	1	282	2.0e-111	395	COG0777	Acetyl-CoA carboxylase beta subunit	294
646812896	203	31.18	21	183	8	167	1.0e-20	93.1	COG0352	Thiamine monophosphate synthase	211
646812897	153	35.26	3	153	2	155	2.0e-32	131	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
646812898	118	33.62	3	118	2	116	7.0e-12	62.7	COG1734	RNA polymerase-binding transcription factor DksA	120
646812900	316	39.81	9	314	11	323	1.0e-78	286	COG0042	tRNA-dihydrouridine synthase	323
646812901	270	31.33	2	269	1	300	3.0e-52	198	COG2264	Ribosomal protein L11 methylase PrmA	300
646812902	688	52.14	56	633	13	589	0.0e+00	614	COG0465	ATP-dependent Zn proteases	596
646812903	191	17.96	5	189	27	231	1.0e-06	46.4	COG0688	Phosphatidylserine decarboxylase	239
646812904	518	50.6	4	414	1	408	4.0e-115	408	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
646812908	987	26.24	21	885	13	796	2.0e-88	321	COG0249	DNA mismatch repair ATPase MutS	843
646812909	273	23.94	7	273	1	281	2.0e-25	109	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646812910	472	22.74	36	456	62	513	2.0e-34	140	COG0833	Amino acid permease	541
646812911	296	38.99	1	277	51	294	3.0e-63	235	COG4302	Ethanolamine ammonia-lyase, small subunit	294
646812912	466	58.63	5	456	3	452	0.0e+00	680	COG4303	Ethanolamine ammonia-lyase, large subunit	453
646812913	618	33.9	430	605	6	181	1.0e-38	155	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646812916	235	45.34	1	234	2	237	3.0e-72	265	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
646812917	283	43.39	4	283	1	295	3.0e-82	298	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
646812918	201	49.51	1	201	3	202	9.0e-69	253	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
646812919	190	28.21	2	189	40	224	2.0e-17	82.8	COG1040	Predicted amidophosphoribosyltransferases	225
646812920	753	26.04	376	729	14	397	4.0e-32	133	COG0840	Methyl-accepting chemotaxis protein	408
646812921	441	21.58	9	433	18	444	2.0e-40	160	COG0534	Na+-driven multidrug efflux pump	455
646812922	212	27.27	17	203	15	212	7.0e-16	77.6	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
646812923	186	44.87	7	160	2	138	5.0e-32	130	COG1142	Fe-S-cluster-containing hydrogenase component 2	165
646812924	653	32.19	1	489	6	481	2.0e-60	227	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
646812925	307	30.29	3	304	6	309	6.0e-40	158	COG0650	Formate hydrogenlyase subunit 4	309
646812926	215	28.3	4	215	7	218	3.0e-21	95.3	COG4237	Hydrogenase-4 membrane subunit HyfE	218
646812927	494	30.5	3	493	1	490	2.0e-49	190	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
646812928	579	47.76	182	559	4	381	8.0e-113	401	COG3261	Ni,Fe-hydrogenase III large subunit	382
646812930	271	63.12	24	164	2	142	4.0e-57	215	COG3260	Ni,Fe-hydrogenase III small subunit	148
646812932	150	26.8	1	143	2	150	2.0e-08	52.2	COG0680	Ni,Fe-hydrogenase maturation factor	160
646812933	284	32.04	1	283	5	262	1.0e-37	150	COG2116	Formate/nitrite transporter FocA, FNT family	265
646812937	595	62.25	2	595	6	600	0.0e+00	945	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
646812938	343	32.54	176	342	20	188	2.0e-29	123	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
646812939	311	57.51	1	309	2	313	5.0e-114	404	COG0462	Phosphoribosylpyrophosphate synthetase	314
646812940	346	40.34	5	346	4	356	5.0e-92	331	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
646812941	376	48.91	10	373	1	354	2.0e-115	409	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
646812942	163	34.15	33	155	6	128	2.0e-30	125	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
646812943	340	32.96	4	340	29	373	5.0e-61	228	COG0006	Xaa-Pro aminopeptidase	384
646812944	160	52.05	1	146	1	146	7.0e-53	199	COG0757	3-dehydroquinate dehydratase	146
646812945	408	25.59	1	405	2	405	3.0e-47	182	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
646812946	295	36.71	63	294	80	316	4.0e-47	181	COG0616	Periplasmic serine protease, ClpP class	317
646812947	399	52.14	1	395	1	393	0.0e+00	518	COG0282	Acetate kinase	396
646812948	332	51.51	3	332	1	325	1.0e-99	356	COG0280	Phosphotransacetylase	327
646812950	333	25.81	238	329	26	118	5.0e-11	62.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646812951	398	55.89	1	397	1	395	0.0e+00	538	COG0282	Acetate kinase	396
646812952	209	28.33	21	197	5	178	2.0e-20	93	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
646812953	605	33.39	8	601	7	609	3.0e-121	429	COG2905	Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains	610
646812954	617	37.07	2	611	5	529	1.0e-129	457	COG4147	Na+(or H+)/acetate symporter ActP	529
646812955	84	44.05	1	84	5	87	4.0e-20	89.3	COG4327	Uncharacterized membrane protein	101
646812956	220	28.32	1	215	1	226	1.0e-32	132	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646812966	168	44.59	17	164	16	162	8.0e-45	173	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
646812967	450	27.89	6	438	4	408	4.0e-66	245	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
646812968	908	43.38	1	907	1	929	0.0e+00	997	COG0060	Isoleucyl-tRNA synthetase	933
646812970	92	37.35	2	82	3	85	8.0e-15	71.9	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
646812972	425	39.43	59	425	91	472	1.0e-89	323	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
646812977	316	39.81	5	316	14	328	2.0e-63	236	COG0714	MoxR-like ATPase	329
646812978	191	19.65	5	154	5	177	3.0e-07	48.5	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
646812979	604	29.79	262	560	80	408	8.0e-28	118	COG0840	Methyl-accepting chemotaxis protein	408
646812980	266	58.96	1	251	3	252	2.0e-94	339	COG0052	Ribosomal protein S2	252
646812981	348	39.43	1	348	1	295	2.0e-70	259	COG0264	Translation elongation factor EF-Ts	296
646812982	217	37.95	6	217	1	224	1.0e-56	212	COG1136	ABC-type lipoprotein export system, ATPase component	226
646812984	205	53.65	5	196	2	191	1.0e-60	226	COG0194	Guanylate kinase	191
646812985	539	31.82	302	539	4	245	6.0e-50	192	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
646812986	812	35.27	86	812	2	710	0.0e+00	624	COG2217	Cation transport ATPase	713
646812987	75	27.27	4	58	2	56	8.0e-07	45.2	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
646812988	93	34.83	5	93	16	100	1.0e-09	54.6	COG2863	Cytochrome c553	121
646812990	309	35.11	1	309	1	315	2.0e-77	282	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
646812991	181	36.02	8	164	15	171	6.0e-23	100	COG2078	Uncharacterized conserved protein, AMMECR1 domain	203
646812992	265	31.65	1	259	1	278	8.0e-45	173	COG1355	Predicted class III extradiol dioxygenase, MEMO1 family	279
646812993	235	24.77	20	230	6	221	2.0e-22	99.5	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
646812994	282	34.15	7	282	2	286	1.0e-47	183	COG2996	Predicted RNA-binding protein, contains S1 domains,  virulence factor B family	287
646812995	174	51.27	1	154	1	158	1.0e-49	189	COG2077	Peroxiredoxin	158
646812996	396	16.71	10	394	17	389	6.0e-17	82.3	COG3213	Uncharacterized protein involved in response to NO	396
646812997	312	36.14	14	283	1	266	8.0e-59	220	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
646812998	180	28.33	2	174	12	191	1.0e-18	86.1	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
646812999	549	22.48	1	545	6	535	1.0e-53	204	COG2303	Choline dehydrogenase or related flavoprotein	542
646813001	680	28.82	4	674	1	640	1.0e-92	334	COG0210	Superfamily I DNA or RNA helicase	655
646813002	905	37.82	665	896	2	239	4.0e-51	197	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
646813003	366	32.96	186	362	2	179	1.0e-38	154	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646813004	882	47.89	1	881	1	875	0.0e+00	1015	COG0525	Valyl-tRNA synthetase	877
646813006	487	20.91	1	429	3	369	8.0e-17	82.2	COG1252	NADH dehydrogenase, FAD-containing subunit	405
646813013	384	29.21	10	359	14	358	2.0e-34	140	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646813014	1045	49.37	1	1032	1	1008	0.0e+00	951	COG0841	Multidrug efflux pump subunit AcrB	1009
646813015	462	33.11	12	457	2	444	7.0e-77	281	COG1538	Outer membrane protein TolC	457
646813016	302	62.25	1	302	1	302	0.0e+00	463	COG1897	Homoserine trans-succinylase	307
646813018	1028	22.24	4	1024	1	1009	0.0e+00	482	COG0841	Multidrug efflux pump subunit AcrB	1009
646813019	741	21.57	538	739	28	231	7.0e-23	103	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
646813020	215	31.71	34	192	45	191	1.0e-27	116	COG3672	Predicted transglutaminase-like cysteine proteinase	191
646813021	437	20.27	20	385	30	394	5.0e-22	99.1	COG2814	Predicted arabinose efflux permease, MFS family	394
646813022	196	44.22	1	196	2	194	3.0e-44	171	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
646813026	254	37.55	1	254	2	266	2.0e-52	198	COG0345	Pyrroline-5-carboxylate reductase	266
646813027	222	24.88	9	221	3	215	1.0e-26	113	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
646813028	805	43.41	12	805	9	774	0.0e+00	855	COG0466	ATP-dependent Lon protease, bacterial type	782
646813030	175	24.04	6	174	29	209	3.0e-09	55.1	COG0705	Membrane associated serine protease, rhomboid family	228
646813031	421	26.7	1	387	2	354	3.0e-47	183	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
646813032	133	25.19	2	132	6	131	1.0e-16	78.8	COG5485	Predicted ester cyclase	131
646813033	258	19.05	5	258	51	320	3.0e-22	99.3	COG0598	Mg2+ and Co2+ transporter CorA	322
646813034	348	19.32	1	347	1	347	1.0e-08	54	COG1363	Putative aminopeptidase FrvX	355
646813035	348	33.79	35	313	38	325	7.0e-46	177	COG3608	Predicted deacylase	331
646813036	310	33.54	1	290	1	315	6.0e-50	191	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
646813037	141	30.94	2	134	21	158	6.0e-19	86.9	COG4067	Uncharacterized conserved protein	162
646813038	203	22.22	3	203	6	212	3.0e-22	98.5	COG3762	Uncharacterized membrane protein	213
646813039	308	29.77	2	308	6	271	2.0e-45	176	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
646813040	196	46.39	1	194	1	185	5.0e-50	190	COG1704	Uncharacterized conserved protein	185
646813042	703	30.33	397	700	76	408	7.0e-33	136	COG0840	Methyl-accepting chemotaxis protein	408
646813043	145	34.23	25	135	12	122	8.0e-14	69.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
646813044	237	28.57	3	216	4	240	1.0e-34	140	COG0300	Short-chain dehydrogenase	265
646813046	720	32.64	485	716	1	239	6.0e-46	179	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
646813048	221	29.78	6	219	2	225	1.0e-37	150	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646813049	615	29.7	299	603	80	408	2.0e-26	114	COG0840	Methyl-accepting chemotaxis protein	408
646813050	407	22.39	143	403	74	329	8.0e-27	114	COG0642	Signal transduction histidine kinase	336
646813052	236	27.94	5	232	6	249	2.0e-36	146	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646813055	190	33.5	2	190	1	205	4.0e-32	131	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
646813057	164	47.37	6	138	12	144	6.0e-33	133	COG2847	Copper(I)-binding protein	151
646813058	429	45.45	1	424	1	386	4.0e-99	355	COG3004	Na+/H+ antiporter NhaA	390
646813059	121	28.26	1	120	5	139	2.0e-16	77.7	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
646813060	287	28.05	1	287	9	298	1.0e-46	180	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
646813061	474	25.66	221	469	36	298	5.0e-33	136	COG2215	ABC-type nickel/cobalt efflux system, permease component RcnA	303
646813062	641	24.62	221	593	1	397	1.0e-26	115	COG0840	Methyl-accepting chemotaxis protein	408
646813063	715	25.79	317	640	60	408	2.0e-27	118	COG0840	Methyl-accepting chemotaxis protein	408
646813064	485	38.16	3	485	5	488	0.0e+00	494	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
646813067	747	36.26	574	743	14	180	9.0e-36	145	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646813068	131	29.32	1	131	6	136	7.0e-09	53.1	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
646813071	113	33.98	1	103	5	105	3.0e-23	100	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
646813072	135	33.82	2	135	7	142	7.0e-28	116	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
646813073	391	41.81	2	386	8	403	3.0e-111	395	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
646813075	246	53.06	1	244	3	243	9.0e-81	293	COG0396	Fe-S cluster assembly ATPase SufC	251
646813076	477	40	35	475	1	412	1.0e-118	420	COG0719	Fe-S cluster assembly scaffold protein SufB	412
646813077	398	50.13	1	388	1	386	0.0e+00	466	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
646813078	326	36.67	11	148	3	143	9.0e-26	111	COG0822	NifU homolog involved in Fe-S cluster formation	150
646813079	497	38.74	24	497	2	469	2.0e-123	436	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646813080	506	55.95	1	504	4	499	0.0e+00	750	COG0554	Glycerol kinase	499
646813081	565	22.39	59	511	29	432	1.0e-19	91.6	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
646813082	92	51.65	3	92	7	97	2.0e-15	73.9	COG5477	Predicted small integral membrane protein	97
646813083	275	32.5	1	275	1	280	2.0e-46	179	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
646813084	289	30.58	1	288	4	294	4.0e-46	178	COG1175	ABC-type sugar transport system, permease component	295
646813085	359	37.78	1	351	1	338	4.0e-88	318	COG3839	ABC-type sugar transport system, ATPase component	338
646813086	362	36.42	1	346	2	335	3.0e-81	295	COG3839	ABC-type sugar transport system, ATPase component	338
646813087	519	33.08	1	518	8	530	3.0e-125	442	COG0578	Glycerol-3-phosphate dehydrogenase	532
646813088	243	32.2	4	235	3	236	2.0e-43	169	COG2188	DNA-binding transcriptional regulator, GntR family	236
646813089	241	31.2	4	233	3	236	3.0e-44	171	COG2188	DNA-binding transcriptional regulator, GntR family	236
646813090	460	49.78	13	460	16	459	0.0e+00	555	COG0165	Argininosuccinate lyase	459
646813091	300	25.16	4	160	3	157	8.0e-15	74.6	COG0835	Chemotaxis signal transduction protein	165
646813092	214	31.97	6	214	15	258	9.0e-52	196	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
646813093	161	46.71	6	157	1	151	1.0e-34	139	COG0782	Transcription elongation factor, GreA/GreB family	151
646813094	233	23.22	10	210	1	211	8.0e-17	80.7	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
646813096	657	60.61	1	657	2	658	0.0e+00	963	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
646813100	214	45.93	6	213	3	211	3.0e-67	248	COG0177	Endonuclease III	211
646813103	660	16.55	9	660	51	768	2.0e-22	101	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
646813104	657	21.01	40	657	57	699	1.0e-24	108	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
646813105	409	26.47	183	378	4	188	2.0e-19	90.4	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
646813107	326	27.22	16	326	7	293	3.0e-22	99.3	COG4866	Uncharacterized protein	294
646813109	149	53.15	1	141	1	143	2.0e-44	171	COG0698	Ribose 5-phosphate isomerase RpiB	151
646813111	286	61.92	3	283	2	282	4.0e-110	391	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
646813113	178	34.09	1	87	3	90	5.0e-15	74.1	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
646813114	183	49.73	1	180	2	186	2.0e-58	218	COG0193	Peptidyl-tRNA hydrolase	190
646813115	356	17.53	1	352	1	361	3.0e-24	106	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
646813117	421	36.44	196	420	41	231	7.0e-46	178	COG0860	N-acetylmuramoyl-L-alanine amidase	231
646813118	358	31.59	2	358	7	332	1.0e-57	217	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
646813119	402	41.87	7	401	5	400	2.0e-101	363	COG0162	Tyrosyl-tRNA synthetase	401
646813120	713	32.89	30	696	26	688	0.0e+00	548	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
646813122	235	59.03	1	226	4	229	4.0e-78	284	COG0528	Uridylate kinase	238
646813123	355	16.36	8	352	19	394	1.0e-07	51.6	COG1373	Predicted ATPase, AAA+ superfamily	398
646813124	314	38.96	11	312	3	325	2.0e-87	315	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
646813125	260	45.95	1	259	1	239	3.0e-72	265	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
646813126	469	38.12	6	469	4	458	4.0e-115	408	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
646813128	420	62.14	5	415	3	412	0.0e+00	634	COG0112	Glycine/serine hydroxymethyltransferase	413
646813129	504	55.13	1	494	8	502	0.0e+00	643	COG1190	Lysyl-tRNA synthetase (class II)	502
646813130	244	24.58	4	182	1	176	1.0e-17	83.8	COG1286	Uncharacterized membrane protein, required for colicin V production	182
646813132	355	56.46	2	354	1	356	0.0e+00	473	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
646813133	377	27.07	11	334	2	346	3.0e-45	176	COG0644	Dehydrogenase (flavoprotein)	396
646813134	479	39.04	5	451	5	435	3.0e-108	386	COG0305	Replicative DNA helicase	435
646813135	249	45.53	7	248	9	261	3.0e-70	258	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
646813138	176	44.51	1	172	4	176	7.0e-48	183	COG0241	Histidinol phosphatase or a related phosphatase	181
646813140	336	25.3	11	332	1	313	5.0e-42	165	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646813141	476	46.33	1	473	1	463	0.0e+00	498	COG2870	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase	467
646813142	190	59.2	1	174	1	174	2.0e-66	244	COG0279	Phosphoheptose isomerase	176
646813143	180	47.19	4	180	1	177	4.0e-40	157	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
646813144	403	64.52	13	400	2	390	0.0e+00	654	COG0133	Tryptophan synthase beta chain	396
646813145	231	26.84	40	224	18	207	2.0e-25	109	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
646813146	472	39.61	26	472	34	484	1.0e-119	423	COG0260	Leucyl aminopeptidase	485
646813149	399	41.6	3	374	1	360	1.0e-106	380	COG0787	Alanine racemase	360
646813150	412	23.94	1	412	3	384	4.0e-38	152	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646813151	124	48	1	124	4	128	7.0e-36	142	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
646813152	215	32.23	2	212	8	214	3.0e-41	161	COG2964	Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains	220
646813153	382	36	43	363	1	317	4.0e-57	215	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
646813154	175	25.49	9	159	6	158	1.0e-13	69.6	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
646813155	427	47.63	47	426	1	379	1.0e-85	310	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
646813156	256	25.5	43	234	43	209	1.0e-19	90	COG2173	D-alanyl-D-alanine dipeptidase	211
646813162	325	22.79	66	325	91	382	8.0e-19	87.9	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
646813164	276	32.53	30	274	16	264	3.0e-50	192	COG1526	Formate dehydrogenase assembly factor FdhD	266
646813165	316	21.35	124	298	6	192	6.0e-07	48.7	COG2864	Cytochrome b subunit of formate dehydrogenase	218
646813166	198	43.93	10	175	10	160	1.0e-34	139	COG0437	Fe-S-cluster-containing dehydrogenase component	203
646813170	203	22.12	1	203	1	203	5.0e-08	51.5	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
646813172	299	28.37	86	295	1	207	3.0e-32	132	COG2864	Cytochrome b subunit of formate dehydrogenase	218
646813173	199	41.54	3	190	7	179	3.0e-35	141	COG0437	Fe-S-cluster-containing dehydrogenase component	203
646813177	228	16.5	1	201	1	201	4.0e-07	48.4	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
646813179	381	20.41	28	368	10	347	2.0e-38	153	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646813182	92	39.39	22	86	6	71	4.0e-07	46.5	COG2608	Copper chaperone CopZ	71
646813184	363	20.33	59	346	36	314	5.0e-21	95.9	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
646813187	440	37.6	40	427	1	378	3.0e-79	289	COG1775	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB	379
646813188	325	37.3	15	324	37	345	4.0e-70	258	COG0709	Selenophosphate synthase	346
646813190	448	39.66	54	446	1	395	8.0e-84	304	COG1921	Seryl-tRNA(Sec) selenium transferase	395
646813191	609	29.07	4	452	1	446	4.0e-73	269	COG3276	Selenocysteine-specific translation elongation factor	447
646813195	356	23.77	102	334	45	278	3.0e-12	66.8	COG4974	Site-specific recombinase XerD	300
646813203	248	28.17	5	238	3	253	1.0e-40	160	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
646813207	327	30.03	1	289	5	297	2.0e-34	139	COG2958	Uncharacterized protein	307
646813208	98	31.46	10	98	11	97	2.0e-13	67.5	COG1669	Predicted nucleotidyltransferase	97
646813209	119	40.17	3	119	1	117	2.0e-23	101	COG2361	Uncharacterized conserved protein, contains HEPN domain	117
646813213	288	35.51	7	113	15	120	1.0e-21	97.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646813216	558	64.34	2	558	1	554	0.0e+00	836	COG2759	Formyltetrahydrofolate synthetase	554
646813217	332	33.33	8	317	31	316	8.0e-45	174	COG0226	ABC-type phosphate transport system, periplasmic component	318
646813218	319	37.8	2	317	18	306	2.0e-55	209	COG0573	ABC-type phosphate transport system, permease component	310
646813219	267	41.16	2	266	12	288	2.0e-52	199	COG0581	ABC-type phosphate transport system, permease component	292
646813220	260	61.15	1	260	5	253	3.0e-107	381	COG1117	ABC-type phosphate transport system, ATPase component	253
646813221	169	33.1	3	139	2	134	2.0e-14	72.4	COG0431	NAD(P)H-dependent FMN reductase	184
646813222	299	25.33	1	299	6	308	2.0e-22	99	COG0679	Predicted permease	311
646813223	228	30.94	51	224	62	240	2.0e-33	136	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
646813226	447	27.12	12	417	3	372	5.0e-57	215	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
646813227	299	37.5	6	297	5	298	5.0e-70	257	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
646813228	294	50.7	1	285	1	286	1.0e-81	296	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
646813229	309	35.58	1	309	1	324	6.0e-76	277	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
646813230	385	60.05	1	378	1	378	0.0e+00	491	COG1929	Glycerate kinase	378
646813231	349	19.37	3	345	2	312	2.0e-11	63.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
646813233	499	39.6	7	499	15	499	2.0e-101	362	COG3333	TctA family transporter	504
646813234	510	44.75	112	510	5	381	2.0e-117	416	COG2721	Altronate dehydratase	381
646813236	229	28.7	12	225	14	226	2.0e-30	125	COG1802	DNA-binding transcriptional regulator, GntR family	230
646813237	483	44.77	1	468	3	477	0.0e+00	493	COG0469	Pyruvate kinase	477
646813242	119	38.46	2	118	1	116	1.0e-14	71.6	COG1734	RNA polymerase-binding transcription factor DksA	120
646813243	300	57.75	117	300	8	193	7.0e-60	224	COG0807	GTP cyclohydrolase II	193
646813244	380	22.71	34	373	27	374	2.0e-27	117	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
646813247	367	57.75	1	367	1	372	2.0e-129	455	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
646813249	852	26.03	702	846	15	151	1.0e-08	55.7	COG0835	Chemotaxis signal transduction protein	165
646813252	104	39.56	12	101	3	93	5.0e-17	79.6	COG3123	Uncharacterized conserved protein YaiE, UPF0345 family	94
646813253	222	32.02	1	218	1	225	1.0e-37	149	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646813255	765	29.45	223	547	27	336	9.0e-42	165	COG0642	Signal transduction histidine kinase	336
646813256	425	31.47	17	384	1	366	2.0e-69	256	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646813257	531	37.92	234	529	2	297	7.0e-72	265	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
646813258	370	32.26	24	359	2	308	3.0e-48	186	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
646813259	262	63.11	19	262	3	246	2.0e-100	358	COG4674	ABC-type uncharacterized transport system, ATPase component	249
646813260	231	48.51	1	231	3	237	3.0e-81	295	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
646813262	388	20.84	2	378	8	383	5.0e-29	122	COG2814	Predicted arabinose efflux permease, MFS family	394
646813263	279	31.32	1	279	1	259	9.0e-44	170	COG1237	Metal-dependent hydrolase, beta-lactamase superfamily II	259
646813264	242	56.02	2	242	1	240	3.0e-101	361	COG1126	ABC-type polar amino acid transport system, ATPase component	240
646813265	216	43.06	2	216	7	222	4.0e-51	194	COG0765	ABC-type amino acid transport system, permease component	222
646813266	226	38.64	3	218	1	220	4.0e-47	181	COG0765	ABC-type amino acid transport system, permease component	222
646813267	260	31.46	1	257	2	268	3.0e-33	135	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646813268	231	26.05	1	212	8	218	3.0e-26	112	COG1802	DNA-binding transcriptional regulator, GntR family	230
646813269	334	42.72	2	323	18	334	7.0e-96	344	COG4266	Allantoicase	334
646813270	171	40.52	1	150	2	152	2.0e-40	158	COG3194	Ureidoglycolate hydrolase (allantoin degradation)	168
646813271	226	59.62	109	212	3	106	3.0e-40	158	COG0832	Urease beta subunit	106
646813272	567	68.19	1	567	2	568	0.0e+00	934	COG0804	Urease alpha subunit	568
646813273	148	26.15	20	148	22	151	4.0e-12	64.1	COG2371	Urease accessory protein UreE	155
646813274	232	20.87	7	232	1	229	2.0e-15	76.1	COG0830	Urease accessory protein UreF	229
646813275	195	46.88	3	192	14	197	3.0e-48	184	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
646813276	129	32.31	2	128	9	136	5.0e-17	80.3	COG0848	Biopolymer transport protein ExbD	137
646813278	236	21.88	20	233	21	243	2.0e-11	63.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
646813279	276	27.7	1	264	3	296	2.0e-43	169	COG0611	Thiamine monophosphate kinase	317
646813280	362	30.19	1	362	1	397	2.0e-57	216	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
646813282	728	26.65	306	599	88	405	2.0e-28	121	COG0840	Methyl-accepting chemotaxis protein	408
646813283	186	36	1	184	1	200	2.0e-43	168	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
646813284	344	28.75	1	308	3	294	2.0e-50	193	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
646813285	239	16.79	9	236	6	277	9.0e-16	77.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646813286	478	28.12	147	478	94	441	8.0e-57	215	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
646813288	163	35.92	19	160	1	138	9.0e-28	116	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
646813290	119	29.46	10	115	18	128	7.0e-20	89.2	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
646813291	413	21.09	1	409	3	377	5.0e-38	152	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646813292	444	29.75	22	443	26	412	1.0e-67	250	COG0232	dGTP triphosphohydrolase	412
646813295	775	28.79	420	724	80	408	1.0e-30	128	COG0840	Methyl-accepting chemotaxis protein	408
646813302	104	58.82	1	102	3	104	3.0e-34	136	COG0051	Ribosomal protein S10	104
646813303	191	35.41	1	191	2	210	3.0e-37	148	COG0087	Ribosomal protein L3	218
646813304	195	34.72	8	194	16	208	6.0e-37	147	COG0088	Ribosomal protein L4	214
646813305	93	42.7	7	93	5	93	8.0e-14	68.7	COG0089	Ribosomal protein L23	94
646813306	275	56.88	1	275	1	275	5.0e-100	357	COG0090	Ribosomal protein L2	275
646813307	92	66.67	1	90	1	90	1.0e-32	131	COG0185	Ribosomal protein S19	93
646813308	110	47.75	1	107	10	120	5.0e-27	112	COG0091	Ribosomal protein L22	120
646813309	232	57.66	12	232	1	222	4.0e-70	257	COG0092	Ribosomal protein S3	233
646813310	141	53.52	1	140	2	143	6.0e-42	163	COG0197	Ribosomal protein L16/L10AE	146
646813312	84	50.6	1	83	4	86	2.0e-17	80.6	COG0186	Ribosomal protein S17	87
646813313	122	77.05	1	122	1	122	1.0e-48	184	COG0093	Ribosomal protein L14	122
646813315	182	53.33	2	180	1	180	1.0e-59	222	COG0094	Ribosomal protein L5	180
646813316	61	47.54	1	61	1	61	6.0e-17	79.1	COG0199	Ribosomal protein S14	61
646813317	132	49.24	1	132	2	132	2.0e-37	147	COG0096	Ribosomal protein S8	132
646813318	178	53.07	1	177	1	178	1.0e-48	185	COG0097	Ribosomal protein L6P/L9E	178
646813319	119	37.19	7	119	5	125	1.0e-23	102	COG0256	Ribosomal protein L18	125
646813320	147	60.14	5	146	20	162	7.0e-47	179	COG0098	Ribosomal protein S5	181
646813321	132	45.31	1	123	1	128	2.0e-21	94.9	COG0200	Ribosomal protein L15	152
646813322	420	45.65	1	415	15	430	3.0e-100	359	COG0201	Preprotein translocase subunit SecY	436
646813323	252	41.34	1	251	1	251	2.0e-71	262	COG0024	Methionine aminopeptidase	255
646813324	73	63.01	1	73	1	72	7.0e-23	98.7	COG0361	Translation initiation factor IF-1	75
646813325	372	30.94	187	365	2	180	2.0e-32	133	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646813327	222	30.35	34	221	1	201	1.0e-31	129	COG1573	Uracil-DNA glycosylase	202
646813329	583	56.97	1	580	1	585	0.0e+00	850	COG0173	Aspartyl-tRNA synthetase	585
646813330	266	23.08	23	224	37	252	2.0e-16	79.7	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
646813331	576	20.25	22	564	1	472	2.0e-30	127	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
646813332	212	45.75	1	212	1	177	2.0e-51	195	COG0563	Adenylate kinase or related kinase	178
646813333	189	35.87	3	185	1	177	1.0e-32	133	COG0563	Adenylate kinase or related kinase	178
646813334	251	23.95	5	229	2	237	8.0e-28	117	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
646813336	340	29.35	1	340	4	359	2.0e-62	232	COG0787	Alanine racemase	360
646813337	610	35.23	1	607	3	581	3.0e-127	449	COG0322	Excinuclease UvrABC, nuclease subunit	581
646813341	664	29.18	434	661	8	240	3.0e-48	187	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
646813343	289	21.62	3	279	4	293	3.0e-12	66.1	COG1397	ADP-ribosylglycohydrolase	314
646813344	207	24.47	5	184	4	189	2.0e-23	102	COG3531	Predicted protein-disulfide isomerase , contains CxxC motif	212
646813350	261	39.18	4	261	1	261	5.0e-66	244	COG0708	Exonuclease III	261
646813351	221	20.13	44	197	4	138	6.0e-15	74.5	COG1225	Peroxiredoxin	157
646813354	304	30.29	1	304	2	308	7.0e-31	128	COG0679	Predicted permease	311
646813355	478	48.46	1	448	3	452	0.0e+00	469	COG1115	Na+/alanine symporter	452
646813356	374	22.52	75	372	35	327	4.0e-30	126	COG0642	Signal transduction histidine kinase	336
646813357	228	28.32	15	227	3	226	5.0e-26	111	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646813359	1183	29.14	360	706	12	327	1.0e-44	175	COG0642	Signal transduction histidine kinase	336
646813360	533	19.01	60	533	80	437	1.0e-26	115	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
646813362	195	26.47	2	195	1	187	4.0e-25	108	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
646813363	300	32.73	190	299	17	126	2.0e-21	96.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646813364	124	44.25	11	121	7	118	6.0e-17	79.7	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
646813365	336	26.57	3	199	1	201	3.0e-27	116	COG1335	Nicotinamidase-related amidase	205
646813366	284	30.3	185	283	24	122	2.0e-16	80.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646813368	387	20.05	1	381	9	386	2.0e-16	80.6	COG2814	Predicted arabinose efflux permease, MFS family	394
646813369	391	18.72	1	381	9	386	7.0e-17	81.8	COG2814	Predicted arabinose efflux permease, MFS family	394
646813371	201	22.22	1	161	5	164	3.0e-11	62	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646813372	99	29.67	1	91	3	89	1.0e-15	74.9	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
646813373	288	20	4	270	1	267	2.0e-23	103	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
646813374	290	20.79	15	283	5	279	2.0e-26	113	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646813375	196	18.97	1	174	8	179	1.0e-09	56.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646813376	246	15.18	10	211	8	263	1.0e-08	53.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646813377	283	35	184	283	23	122	5.0e-19	88.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646813378	174	44.52	17	171	20	170	2.0e-42	164	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
646813381	275	22.93	1	256	33	285	5.0e-26	111	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
646813382	374	27.06	10	372	18	390	9.0e-50	191	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646813384	649	42.86	468	647	2	181	5.0e-46	179	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646813385	490	17.95	1	474	3	432	1.0e-23	104	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
646813387	249	24.79	101	215	11	128	7.0e-12	64.3	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
646813388	482	42.49	7	477	1	469	0.0e+00	504	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646813389	316	31.2	1	314	1	342	8.0e-74	270	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
646813390	202	21.76	21	202	8	198	6.0e-10	57.5	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
646813392	392	21.99	4	365	1	355	1.0e-20	94.6	COG0686	Alanine dehydrogenase	371
646813393	187	29.52	7	171	2	166	1.0e-18	86.1	COG4843	Uncharacterized protein YebE, UPF0316 family	179
646813394	320	29.97	3	317	1	312	5.0e-60	225	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
646813396	289	21.77	1	288	1	291	1.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
646813397	342	42.2	14	339	12	333	4.0e-67	248	COG2855	Uncharacterized membrane protein YadS	334
646813398	471	63.12	3	463	2	462	0.0e+00	693	COG1027	Aspartate ammonia-lyase	471
646813400	869	20.27	576	867	42	327	2.0e-26	115	COG0642	Signal transduction histidine kinase	336
646813401	236	26.92	7	234	2	226	4.0e-25	108	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646813403	179	20.22	2	176	13	190	1.0e-09	56.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646813406	337	32.83	6	331	3	321	4.0e-61	228	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
646813407	651	39.05	3	602	20	610	5.0e-119	421	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
646813408	635	26.95	324	632	76	408	7.0e-28	119	COG0840	Methyl-accepting chemotaxis protein	408
646813410	395	34.58	1	391	3	400	1.0e-72	267	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
646813412	384	40.31	3	380	5	385	2.0e-100	359	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
646813413	345	32.22	1	329	1	326	4.0e-64	238	COG3938	Proline racemase	341
646813414	385	28.11	6	367	1	326	2.0e-52	199	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646813415	148	30	1	148	4	150	6.0e-17	80.4	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
646813416	427	41.64	48	424	1	377	4.0e-77	282	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
646813417	195	25.61	22	185	8	169	3.0e-16	78.8	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
646813418	337	28.61	1	331	2	332	1.0e-47	183	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
646813419	394	27.99	5	394	3	383	2.0e-69	256	COG0006	Xaa-Pro aminopeptidase	384
646813420	464	37.45	4	462	12	469	2.0e-117	416	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646813421	414	31.42	4	413	18	447	4.0e-96	345	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
646813424	360	24.68	125	358	48	282	4.0e-12	66.1	COG0842	ABC-type multidrug transport system, permease component	286
646813425	369	30.77	159	366	75	282	3.0e-12	66.5	COG0842	ABC-type multidrug transport system, permease component	286
646813426	565	45.04	323	561	4	245	4.0e-68	252	COG1131	ABC-type multidrug transport system, ATPase component	293
646813427	326	22.26	32	321	47	320	6.0e-31	128	COG1566	Multidrug resistance efflux pump	352
646813428	170	43.71	1	167	1	167	2.0e-45	175	COG1528	Ferritin	167
646813429	306	42.48	3	306	4	309	1.0e-83	303	COG1227	Inorganic pyrophosphatase/exopolyphosphatase	311
646813430	255	23.72	6	251	1	253	2.0e-12	66.2	COG0730	Uncharacterized membrane protein YfcA	258
646813431	257	35	157	255	23	122	7.0e-20	91.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646813432	433	32.6	26	432	1	379	2.0e-83	303	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
646813434	96	35	18	96	19	97	4.0e-11	59.8	COG1669	Predicted nucleotidyltransferase	97
646813435	122	29.46	11	122	10	113	1.0e-11	62.2	COG2361	Uncharacterized conserved protein, contains HEPN domain	117
646813436	361	43.51	92	245	1	154	5.0e-41	162	COG4335	3-methyladenine DNA glycosylase AlkC	167
646813437	155	46.98	1	149	1	148	2.0e-39	154	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
646813441	151	27.05	28	148	15	133	7.0e-13	66.8	COG2346	Truncated hemoglobin YjbI	133
646813443	660	33.76	426	655	6	239	1.0e-52	201	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
646813444	474	26.02	1	267	1	262	2.0e-21	97.3	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
646813447	880	24.04	11	572	10	548	8.0e-58	219	COG3008	Paraquat-inducible protein B	553
646813448	475	56.16	2	475	13	490	0.0e+00	672	COG0753	Catalase	496
646813454	637	48.75	3	637	6	622	0.0e+00	676	COG0326	Molecular chaperone, HSP90 family	623
646813456	98	33.98	1	98	2	97	2.0e-15	74.1	COG1669	Predicted nucleotidyltransferase	97
646813457	112	32.71	4	110	6	111	8.0e-18	82.3	COG2361	Uncharacterized conserved protein, contains HEPN domain	117
646813459	273	26.55	1	258	1	273	2.0e-38	152	COG0583	DNA-binding transcriptional regulator, LysR family	297
646813460	159	25.49	2	147	1	150	1.0e-05	42.6	COG1247	L-amino acid N-acyltransferase YncA	169
646813461	693	20.64	32	693	54	768	2.0e-41	164	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
646813462	326	26.02	201	323	1	123	4.0e-16	79.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646813463	293	20.27	1	293	1	264	2.0e-07	50	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
646813464	291	26.05	2	285	7	335	8.0e-52	197	COG1566	Multidrug resistance efflux pump	352
646813466	699	17.91	15	672	1	644	4.0e-49	190	COG1289	Uncharacterized membrane protein YccC	674
646813467	477	19.57	54	471	36	451	1.0e-42	168	COG1538	Outer membrane protein TolC	457
646813468	142	31.4	15	135	2	122	3.0e-09	54.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
646813469	316	28.17	2	312	5	321	3.0e-36	146	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
646813470	599	35.49	2	598	14	614	2.0e-95	343	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
646813474	389	41.73	4	380	7	386	6.0e-100	357	COG1686	D-alanyl-D-alanine carboxypeptidase	389
646813475	209	34.39	21	206	7	194	7.0e-38	150	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
646813476	245	38.52	1	244	2	242	4.0e-71	261	COG1540	Lactam utilization protein B (function unknown)	252
646813478	506	21.09	195	504	23	327	2.0e-28	120	COG0642	Signal transduction histidine kinase	336
646813479	226	22.67	13	224	3	226	5.0e-22	98.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646813480	318	23.75	6	317	14	327	6.0e-43	168	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
646813481	161	25.97	8	157	11	161	5.0e-13	67.2	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
646813482	445	34.65	63	442	1	378	5.0e-65	242	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
646813483	343	25.28	1	254	1	259	9.0e-19	88	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
646813484	178	29.46	17	144	23	151	1.0e-11	62.6	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
646813485	428	35.56	55	427	7	377	2.0e-69	256	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
646813486	267	33.33	2	267	1	267	1.0e-40	159	COG0388	Predicted amidohydrolase	274
646813487	219	41.76	26	195	30	197	4.0e-36	145	COG0684	Regulator of RNase E activity RraA	210
646813488	255	44.88	1	252	12	265	1.0e-82	299	COG4336	Uncharacterized protein YcsI, UPF0317 family	265
646813489	226	25	13	223	3	225	1.0e-22	99.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646813490	608	20.72	279	608	2	327	1.0e-25	111	COG0642	Signal transduction histidine kinase	336
646813491	245	45.31	1	245	2	243	3.0e-87	314	COG1540	Lactam utilization protein B (function unknown)	252
646813492	224	38.46	3	222	1	221	1.0e-59	223	COG2049	Allophanate hydrolase subunit 1	223
646813493	303	39.67	3	303	1	304	1.0e-87	316	COG1984	Allophanate hydrolase subunit 2	314
646813494	176	24.28	5	173	22	194	6.0e-22	97.3	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
646813496	322	33.53	140	311	13	181	1.0e-31	130	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646813499	538	19.43	2	521	23	406	4.0e-24	106	COG1078	HD superfamily phosphohydrolase	421
646813501	458	25.16	4	453	3	436	8.0e-43	168	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
646813502	160	28.83	3	160	11	172	7.0e-25	106	COG0684	Regulator of RNase E activity RraA	210
646813503	72	62.69	6	72	3	67	3.0e-21	93.3	COG1278	Cold shock protein, CspA family	67
646813506	213	21	5	213	33	243	2.0e-13	69.1	COG1651	Protein-disulfide isomerase	244
646813507	197	26.55	29	196	39	215	9.0e-12	63.7	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
646813509	94	35.63	1	87	2	88	5.0e-16	75.8	COG1359	Quinol monooxygenase YgiN	100
646813510	390	42.51	1	390	1	404	2.0e-100	359	COG3347	Rhamnose utilisation protein RhaD, predicted bifunctional aldolase and dehydrogenase	404
646813511	268	28.84	13	268	7	246	5.0e-31	128	COG0584	Glycerophosphoryl diester phosphodiesterase	257
646813512	285	33.45	3	282	1	261	1.0e-41	163	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
646813513	285	34.7	10	277	17	279	6.0e-50	191	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
646813515	295	50.52	1	287	2	290	2.0e-105	375	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
646813516	353	31.01	4	353	13	363	2.0e-50	193	COG0687	Spermidine/putrescine-binding periplasmic protein	363
646813517	520	28.46	1	508	3	500	7.0e-96	344	COG1070	Sugar (pentulose or hexulose) kinase	502
646813518	124	25.77	20	116	36	131	7.0e-09	52.9	COG1917	Cupin domain protein related to quercetin dioxygenase	131
646813523	326	31.72	33	317	51	336	1.0e-58	220	COG2951	Membrane-bound lytic murein transglycosylase B	343
646813526	139	25.33	2	128	10	159	2.0e-10	58.5	COG1495	Disulfide bond formation protein DsbB	170
646813529	591	30.99	6	589	2	564	1.0e-92	334	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
646813531	209	27.44	1	208	1	212	1.0e-26	113	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
646813534	311	34.87	118	305	71	265	2.0e-27	116	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
646813536	236	45.76	1	235	6	237	2.0e-65	241	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
646813537	180	30.91	21	180	7	155	1.0e-23	103	COG1225	Peroxiredoxin	157
646813540	296	23.59	4	280	6	280	3.0e-11	62.5	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
646813542	709	25.62	465	702	15	243	4.0e-31	130	COG1647	Esterase/lipase	243
646813543	786	26.23	138	499	32	382	6.0e-50	193	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646813544	706	37.7	304	603	1	305	3.0e-71	263	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
646813545	423	34.25	2	423	1	391	5.0e-78	285	COG0183	Acetyl-CoA acetyltransferase	392
646813546	573	35.21	32	573	40	607	1.0e-125	443	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
646813547	858	64.72	3	854	1	847	0.0e+00	1267	COG1049	Aconitase B	852
646813548	260	27.99	1	257	1	267	4.0e-39	155	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
646813549	265	33.82	1	265	10	281	1.0e-45	176	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
646813550	287	40.14	1	283	7	290	2.0e-57	216	COG1175	ABC-type sugar transport system, permease component	295
646813551	422	29.59	1	421	5	433	2.0e-45	177	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
646813552	357	49.71	1	348	1	337	2.0e-110	392	COG3839	ABC-type sugar transport system, ATPase component	338
646813553	254	34.94	1	249	1	249	1.0e-58	220	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
646813554	198	21.88	4	193	10	197	4.0e-10	58.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646813555	311	28.43	10	290	49	346	1.0e-61	230	COG1740	Ni,Fe-hydrogenase I small subunit	355
646813556	450	22.35	3	450	5	530	7.0e-59	221	COG0374	Ni,Fe-hydrogenase I large subunit	545
646813557	415	50.14	53	405	3	350	3.0e-123	435	COG1740	Ni,Fe-hydrogenase I small subunit	355
646813558	578	50.7	2	570	1	544	0.0e+00	638	COG0374	Ni,Fe-hydrogenase I large subunit	545
646813559	239	22.48	14	227	18	225	1.0e-16	80.3	COG1969	Ni,Fe-hydrogenase I cytochrome b subunit	227
646813560	191	26.88	1	157	2	160	1.0e-18	86.5	COG0680	Ni,Fe-hydrogenase maturation factor	160
646813562	388	54.27	26	387	1	355	0.0e+00	473	COG1740	Ni,Fe-hydrogenase I small subunit	355
646813563	576	50.18	4	568	2	544	0.0e+00	659	COG0374	Ni,Fe-hydrogenase I large subunit	545
646813564	229	33.64	4	218	10	227	6.0e-48	183	COG1969	Ni,Fe-hydrogenase I cytochrome b subunit	227
646813565	187	29.33	1	149	2	147	4.0e-22	98.1	COG0680	Ni,Fe-hydrogenase maturation factor	160
646813567	742	45.2	4	739	1	744	0.0e+00	797	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
646813568	668	28.18	309	613	80	408	2.0e-28	121	COG0840	Methyl-accepting chemotaxis protein	408
646813573	112	22.32	1	111	1	112	8.0e-09	52.2	COG3370	Uncharacterized protein	113
646813574	382	17.75	49	379	52	388	2.0e-08	54.1	COG2814	Predicted arabinose efflux permease, MFS family	394
646813576	258	40.89	55	251	1	196	2.0e-53	202	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
646813577	93	48.1	1	79	1	79	2.0e-20	91.1	COG0298	Hydrogenase maturation factor	82
646813578	374	53.8	7	374	1	364	0.0e+00	499	COG0409	Hydrogenase maturation factor	364
646813579	239	31.16	1	198	1	187	6.0e-33	134	COG0518	GMP synthase - Glutamine amidotransferase domain	198
646813580	332	46.2	3	332	1	339	2.0e-95	342	COG0309	Hydrogenase maturation factor	339
646813581	113	39.29	1	112	1	112	4.0e-28	116	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
646813582	631	37.85	459	631	3	179	6.0e-38	152	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646813583	375	27.09	23	375	7	364	3.0e-52	199	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646813584	298	42.67	1	296	1	297	2.0e-49	189	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
646813585	346	33.53	11	334	3	309	3.0e-51	195	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
646813586	255	53.41	2	250	4	249	2.0e-94	338	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
646813587	232	53.85	1	231	3	236	6.0e-84	303	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
646813593	616	36.8	108	615	191	728	0.0e+00	497	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
646813594	395	34.43	127	395	14	269	9.0e-52	197	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
646813595	610	40.66	419	599	3	181	2.0e-41	164	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646813596	434	21.62	183	434	7	262	1.0e-14	74.8	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
646813598	220	37.79	1	217	1	216	4.0e-52	198	COG2884	ABC-type ATPase involved in cell division	223
646813599	400	30.05	109	290	30	222	9.0e-34	138	COG0220	tRNA G46 methylase TrmB	227
646813600	424	28.53	63	408	2	333	1.0e-36	147	COG3401	Fibronectin type 3 domain	343
646813601	320	41.4	8	286	10	287	2.0e-66	246	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
646813602	368	32.81	1	366	3	381	2.0e-49	189	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
646813603	283	36.75	1	283	2	303	1.0e-60	226	COG0010	Arginase family enzyme	305
646813606	268	21	52	267	36	241	1.0e-08	54	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
646813607	426	55.87	2	426	4	429	0.0e+00	574	COG0001	Glutamate-1-semialdehyde aminotransferase	432
646813608	104	53.26	12	103	3	94	1.0e-28	117	COG3123	Uncharacterized conserved protein YaiE, UPF0345 family	94
646813612	626	52.28	343	625	60	342	6.0e-85	308	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
646813613	166	47.16	3	162	6	179	8.0e-49	186	COG0066	3-isopropylmalate dehydratase small subunit	191
646813614	355	53.87	1	355	1	347	5.0e-120	424	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
646813615	309	18.18	5	308	18	327	3.0e-18	85.9	COG0618	nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs	332
646813616	251	53.31	1	242	2	238	5.0e-89	320	COG1126	ABC-type polar amino acid transport system, ATPase component	240
646813617	221	37.39	1	219	1	220	2.0e-44	172	COG0765	ABC-type amino acid transport system, permease component	222
646813618	265	26.12	1	253	1	266	6.0e-28	118	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646813619	468	24.74	6	464	7	406	1.0e-53	204	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
646813620	120	20.63	1	119	17	138	9.0e-11	58.9	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
646813621	804	21.9	467	803	20	335	5.0e-19	90.2	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
646813622	120	60.17	1	118	1	118	6.0e-41	159	COG0099	Ribosomal protein S13	121
646813623	130	63.08	1	130	1	129	1.0e-39	155	COG0100	Ribosomal protein S11	129
646813624	208	54.29	1	208	1	205	1.0e-56	213	COG0522	Ribosomal protein S4 or related protein	205
646813625	332	38.19	11	317	4	310	2.0e-62	232	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
646813626	116	61.21	1	116	1	116	3.0e-39	153	COG0203	Ribosomal protein L17	116
646813627	453	48.18	49	453	76	471	3.0e-125	442	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
646813628	481	31.51	253	471	1	170	1.0e-32	134	COG0516	IMP dehydrogenase/GMP reductase	170
646813630	66	66.67	1	66	1	66	7.0e-19	85.3	COG3655	DNA-binding transcriptional regulator, XRE family	73
646813632	89	40.7	4	87	1	84	2.0e-15	73.8	COG4115	Toxin component of the Txe-Axe toxin-antitoxin module, Txe/YoeB family	84
646813634	111	35.58	5	103	1	103	7.0e-21	92.3	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
646813635	81	34.15	1	81	1	82	1.0e-12	65	COG2336	Antitoxin component of the MazEF toxin-antitoxin module	82
646813637	207	29.06	7	207	6	208	8.0e-27	113	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646813640	87	50.57	1	87	3	88	1.0e-21	94.6	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
646813641	164	31.95	1	164	1	151	1.0e-20	92.4	COG0716	Flavodoxin	151
646813642	115	27.27	8	106	12	108	1.0e-14	71.9	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
646813644	191	24.02	12	186	25	203	4.0e-21	95	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
646813648	366	39.82	5	342	3	334	4.0e-57	215	COG2603	tRNA 2-selenouridine synthase SelU, contains rhodanese domain	334
646813649	399	27.27	1	381	3	380	7.0e-65	241	COG1252	NADH dehydrogenase, FAD-containing subunit	405
646813650	250	20.85	1	182	4	209	2.0e-10	59.5	COG2129	Predicted phosphoesterase, related to the Icc protein	226
646813653	185	37.1	1	182	15	199	6.0e-41	160	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
646813654	334	43.84	3	328	6	338	1.0e-90	326	COG1816	Adenosine deaminase	345
646813655	310	45.63	4	310	1	298	4.0e-87	314	COG2040	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)	300
646813657	210	29.76	1	204	1	204	5.0e-26	111	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646813659	204	21.24	1	191	1	189	1.0e-15	76.6	COG3124	Acyl carrier protein phosphodiesterase	193
646813662	157	31.62	18	153	18	149	9.0e-24	103	COG2731	Beta-galactosidase, beta subunit	154
646813663	353	45.64	8	350	18	359	1.0e-115	409	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
646813664	610	37.17	1	491	3	528	1.0e-121	430	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
646813665	149	23.44	7	124	1	119	1.0e-07	49.1	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
646813666	243	23.61	20	243	3	235	3.0e-26	112	COG0412	Dienelactone hydrolase	236
646813667	368	40.23	13	365	24	366	2.0e-101	363	COG2021	Homoserine acetyltransferase	368
646813669	220	43.3	2	220	1	224	1.0e-51	196	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
646813672	483	24.31	2	483	7	481	2.0e-42	167	COG0286	Type I restriction-modification system, DNA methylase subunit	489
646813673	383	20.77	8	380	8	391	1.0e-18	87.8	COG0732	Restriction endonuclease S subunit	391
646813676	227	32.77	3	224	6	242	6.0e-34	137	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
646813677	1079	66.58	13	404	1	393	0.0e+00	517	COG0458	Carbamoylphosphate synthase large subunit	400
646813679	430	24.38	1	316	3	260	5.0e-09	56.3	COG1672	Predicted ATPase, archaeal AAA+ ATPase superfamily	359
646813690	396	23.5	18	237	44	276	7.0e-22	98.6	COG0790	TPR repeat	292
646813692	151	30.71	6	145	3	140	2.0e-24	105	COG2994	ACP:hemolysin acyltransferase (hemolysin-activating protein)	148
646813693	425	15.93	20	416	44	450	6.0e-31	128	COG1538	Outer membrane protein TolC	457
646813694	714	40.46	12	708	15	709	0.0e+00	603	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
646813695	440	17.53	62	419	52	341	4.0e-11	63	COG1566	Multidrug resistance efflux pump	352
646813696	312	32.48	1	306	3	300	1.0e-62	233	COG4974	Site-specific recombinase XerD	300
646813702	237	26.55	12	226	2	226	6.0e-22	98.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646813706	403	15.5	25	401	46	445	7.0e-33	135	COG1538	Outer membrane protein TolC	457
646813708	388	23.82	7	318	16	289	9.0e-20	91.6	COG1566	Multidrug resistance efflux pump	352
646813709	708	29.44	34	693	25	697	8.0e-111	394	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
646813711	595	26.77	398	590	21	217	4.0e-27	116	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
646813712	235	28.45	5	235	1	227	9.0e-22	97.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646813713	538	29.42	4	538	8	554	1.0e-84	307	COG2831	Hemolysin activation/secretion protein	554
646813716	329	27.19	17	329	6	333	9.0e-50	190	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
646813718	118	28.7	1	115	7	121	1.0e-12	65.5	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
646813719	237	39.91	9	236	2	228	7.0e-45	174	COG1346	Putative effector of murein hydrolase	230
646813720	373	22.98	1	371	1	389	4.0e-37	149	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
646813721	789	21.22	1	789	1	895	6.0e-32	133	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
646813732	316	48.94	30	310	2	283	1.0e-97	350	COG3129	23S rRNA A1618 N6-methylase RlmF	292
646813733	193	28.65	6	191	5	195	8.0e-32	130	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
646813734	297	20	8	294	4	259	3.0e-16	79.3	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
646813735	711	24.16	35	708	30	720	8.0e-68	252	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
646813736	151	46.05	1	150	2	153	9.0e-49	185	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
646813737	202	23.49	1	165	3	168	2.0e-12	66.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646813739	477	19.58	161	400	10	233	4.0e-10	59.9	COG0668	Small-conductance mechanosensitive channel	316
646813743	212	25.48	8	204	7	214	9.0e-24	103	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
646813746	344	46.65	1	344	2	357	2.0e-113	402	COG0337	3-dehydroquinate synthetase	360
646813747	551	20.12	208	549	5	312	6.0e-16	79.6	COG0668	Small-conductance mechanosensitive channel	316
646813748	421	32.95	7	421	2	435	9.0e-103	367	COG0621	tRNA A37 methylthiotransferase MiaB	437
646813749	493	39.23	110	493	144	584	8.0e-91	328	COG0465	ATP-dependent Zn proteases	596
646813751	176	47.77	4	158	9	162	2.0e-46	178	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
646813752	444	27.31	3	441	7	457	1.0e-30	127	COG0471	Di- and tricarboxylate transporter	461
646813754	733	27.61	2	733	14	753	4.0e-106	379	COG1193	dsDNA-specific endonuclease/ATPase MutS2	753
646813757	366	29.95	1	366	13	406	8.0e-63	234	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
646813760	159	25.78	4	127	2	129	2.0e-08	51.9	COG0645	Predicted kinase	170
646813761	238	42.8	1	238	1	237	2.0e-42	165	COG2859	Uncharacterized protein	237
646813762	329	34.06	4	322	1	308	2.0e-65	243	COG0039	Malate/lactate dehydrogenase	313
646813763	450	16.41	3	447	7	459	5.0e-11	62.6	COG0471	Di- and tricarboxylate transporter	461
646813765	225	29.46	10	223	2	224	1.0e-28	120	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646813766	529	20.3	70	499	99	550	3.0e-26	113	COG0747	ABC-type transport system, periplasmic component	556
646813767	550	23.68	288	549	71	327	9.0e-25	108	COG0642	Signal transduction histidine kinase	336
646813768	195	12.78	15	194	13	188	5.0e-07	47.7	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
646813769	827	29.32	7	814	3	765	0.0e+00	510	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
646813770	147	25.32	2	147	4	155	2.0e-10	58.5	COG3708	Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain	157
646813771	455	23.29	28	444	1	416	9.0e-31	128	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
646813773	230	56.33	1	229	1	228	5.0e-76	277	COG1794	Aspartate/glutamate racemase	230
646813774	217	37.44	7	216	2	207	1.0e-42	166	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
646813777	123	38.32	1	107	1	107	2.0e-26	111	COG1733	DNA-binding transcriptional regulator, HxlR family	120
646813778	326	20.55	32	321	4	292	4.0e-09	55.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
646813779	193	28.16	2	192	1	188	2.0e-24	105	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
646813780	249	28.5	1	189	2	207	2.0e-20	93.1	COG0778	Nitroreductase	207
646813781	339	36.75	6	338	1	326	9.0e-62	230	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646813782	98	29.29	1	98	1	98	4.0e-12	63.1	COG1359	Quinol monooxygenase YgiN	100
646813783	100	31.4	1	83	3	87	2.0e-09	53.8	COG1359	Quinol monooxygenase YgiN	100
646813784	342	44.61	1	327	3	334	9.0e-100	357	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
646813785	307	20.35	11	293	9	290	4.0e-06	45.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
646813786	190	23.24	8	190	5	178	8.0e-29	120	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
646813787	377	50.26	1	376	2	383	2.0e-129	455	COG1979	Alcohol dehydrogenase YqhD, Fe-dependent ADH family	384
646813788	209	26.85	1	209	1	206	2.0e-26	112	COG0778	Nitroreductase	207
646813789	885	29.74	472	752	100	405	1.0e-32	135	COG0840	Methyl-accepting chemotaxis protein	408
646813791	307	22.44	3	304	1	306	7.0e-15	75	COG0679	Predicted permease	311
646813792	490	34.63	10	394	3	383	4.0e-80	292	COG0301	Adenylyl- and sulfurtransferase ThiI, participates in tRNA 4-thiouridine and thiamine biosynthesis	383
646813794	528	40.15	1	528	3	528	0.0e+00	534	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
646813795	1646	22.74	283	1119	2	849	2.0e-80	295	COG3899	Predicted ATPase	849
646813797	161	44	1	150	4	152	4.0e-40	157	COG1607	Acyl-CoA hydrolase	157
646813798	648	47.04	3	648	8	666	0.0e+00	761	COG0272	NAD-dependent DNA ligase	667
646813802	282	18.02	172	282	41	151	4.0e-08	52.3	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
646813803	219	37.44	1	218	1	226	1.0e-48	186	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646813804	455	25.24	146	455	20	329	1.0e-36	147	COG0642	Signal transduction histidine kinase	336
646813805	332	29.5	7	321	2	306	2.0e-37	149	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
646813806	500	34.73	1	500	1	495	5.0e-90	325	COG3333	TctA family transporter	504
646813808	332	29.81	11	326	4	311	2.0e-38	153	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
646813809	125	24.19	1	123	11	134	1.0e-11	62.2	COG3439	Uncharacterized conserved protein, DUF302 family	137
646813810	426	24.83	1	425	4	408	2.0e-37	150	COG2195	Di- or tripeptidase	414
646813812	938	27.54	649	906	6	281	2.0e-36	148	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
646813814	322	28.74	145	310	18	181	2.0e-28	119	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646813815	197	22.49	1	187	12	220	1.0e-22	99	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
646813816	273	35.9	1	270	3	266	2.0e-59	222	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
646813818	354	31.74	118	345	12	240	4.0e-48	185	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
646813819	213	51.4	1	213	2	214	2.0e-73	268	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
646813821	408	45.07	113	396	5	283	1.0e-85	310	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
646813822	247	27.87	6	245	10	253	8.0e-32	130	COG3496	Uncharacterized conserved protein, DUF1365 family	261
646813823	411	39.28	1	408	9	422	9.0e-98	350	COG2907	Predicted NAD/FAD-binding protein	447
646813824	165	31.21	1	165	1	172	4.0e-23	101	COG3040	Bacterial lipocalin	174
646813825	414	25.47	3	411	10	437	5.0e-40	158	COG2211	Na+/melibiose symporter or related transporter	467
646813827	250	21.4	1	250	6	257	3.0e-27	115	COG0300	Short-chain dehydrogenase	265
646813828	404	57.58	8	396	1	388	0.0e+00	568	COG0133	Tryptophan synthase beta chain	396
646813830	374	46.56	1	374	1	370	9.0e-112	397	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
646813831	190	31.31	2	190	1	198	9.0e-49	186	COG0353	Recombinational DNA repair protein RecR	198
646813835	229	36.44	3	225	8	232	1.0e-40	159	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
646813836	108	38.61	5	105	4	104	8.0e-15	72.2	COG1687	Branched-chain amino acid transport protein AzlD	106
646813837	410	21.92	13	392	19	405	6.0e-28	118	COG2848	Uncharacterized conserved protein, UPF0210 family	445
646813839	197	26.16	36	196	27	196	1.0e-13	69.9	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
646813840	166	50	1	166	3	168	9.0e-58	216	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
646813843	304	25.69	49	297	68	318	2.0e-27	117	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
646813844	364	23.17	1	360	13	406	2.0e-35	143	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
646813845	414	55.07	3	414	1	403	0.0e+00	575	COG0137	Argininosuccinate synthase	403
646813846	87	35.37	1	82	9	90	6.0e-15	72.3	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
646813847	327	45.74	9	325	26	338	3.0e-97	348	COG0547	Anthranilate phosphoribosyltransferase	338
646813848	139	39.55	10	139	8	137	4.0e-21	93.8	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
646813849	240	61.57	1	240	2	243	1.0e-99	356	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
646813851	241	41.39	1	241	5	244	1.0e-69	256	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
646813852	467	26.17	224	467	86	331	6.0e-26	112	COG0642	Signal transduction histidine kinase	336
646813853	900	44.76	311	900	2	593	0.0e+00	564	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
646813854	236	20.18	15	230	2	227	1.0e-13	70.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646813858	270	35.19	1	268	1	276	3.0e-48	185	COG0682	Prolipoprotein diacylglyceryltransferase	287
646813859	432	27.53	12	431	7	385	3.0e-60	226	COG0247	Fe-S oxidoreductase	388
646813860	455	36.09	8	442	1	414	6.0e-112	398	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
646813861	308	56.86	1	304	6	310	4.0e-122	431	COG0078	Ornithine carbamoyltransferase	310
646813862	704	25.1	1	703	1	672	2.0e-124	440	COG1328	Anaerobic ribonucleoside-triphosphate reductase	700
646813864	225	26.8	9	193	24	213	3.0e-23	101	COG1180	Pyruvate-formate lyase-activating enzyme	260
646813865	226	31.28	10	223	2	227	3.0e-36	145	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646813868	324	58.46	1	323	6	329	0.0e+00	495	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
646813869	187	53.89	1	187	1	193	7.0e-57	213	COG0807	GTP cyclohydrolase II	193
646813870	194	33.5	8	194	13	215	7.0e-30	123	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
646813874	671	41.1	1	671	2	691	0.0e+00	680	COG0751	Glycyl-tRNA synthetase, beta subunit	691
646813878	166	34.97	1	160	4	163	8.0e-26	110	COG3613	Nucleoside 2-deoxyribosyltransferase	172
646813879	299	23.61	106	296	29	244	3.0e-22	99.3	COG1587	Uroporphyrinogen-III synthase	248
646813885	383	21.51	108	364	35	283	7.0e-16	78.7	COG4974	Site-specific recombinase XerD	300
646813889	378	23.69	29	276	25	212	2.0e-16	80.5	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
646813906	343	55.72	4	204	3	203	6.0e-77	281	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
646813908	525	58.46	6	525	11	528	0.0e+00	742	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
646813909	440	65.22	78	440	9	374	3.0e-129	455	COG1883	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit	375
646813910	605	33.12	1	459	1	446	0.0e+00	466	COG5016	Pyruvate/oxaloacetate carboxyltransferase	472
646813911	83	28.4	2	82	3	80	3.0e-07	46.8	COG3630	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit	84
646813915	648	41.8	5	519	5	554	0.0e+00	573	COG0143	Methionyl-tRNA synthetase	558
646813917	281	38	1	278	26	324	1.0e-68	253	COG0158	Fructose-1,6-bisphosphatase	326
646813918	167	31.65	11	161	5	161	9.0e-26	109	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
646813922	429	28.04	3	421	13	458	9.0e-61	227	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
646813923	412	27.11	17	410	28	428	3.0e-54	206	COG0612	Predicted Zn-dependent peptidase	438
646813924	355	44.69	1	355	11	366	4.0e-111	394	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
646813925	753	27.26	1	753	3	766	2.0e-123	437	COG4775	Outer membrane protein assembly factor BamA	766
646813926	276	33.21	1	274	4	277	1.0e-56	213	COG0287	Prephenate dehydrogenase	279
646813927	269	38.35	5	265	7	266	2.0e-61	229	COG0294	Dihydropteroate synthase	274
646813930	402	43.11	1	401	2	447	4.0e-113	401	COG0527	Aspartokinase	447
646813931	167	20.71	15	151	7	140	1.0e-09	56.5	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
646813932	353	38.01	1	327	35	375	5.0e-77	281	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
646813933	274	34.05	1	272	1	277	3.0e-54	205	COG2890	Methylase of polypeptide chain release factors	280
646813934	655	41.27	21	653	37	681	0.0e+00	613	COG0339	Zn-dependent oligopeptidase	683
646813937	351	29.97	47	344	1	289	3.0e-41	162	COG4974	Site-specific recombinase XerD	300
646813939	162	34.57	3	162	7	167	7.0e-34	136	COG3516	Predicted component of the type VI protein secretion system	169
646813940	491	49.9	1	491	1	493	0.0e+00	648	COG3517	Predicted component of the type VI protein secretion system	495
646813941	138	19.29	5	133	14	153	2.0e-11	61.5	COG3518	Predicted component of the type VI protein secretion system	157
646813942	590	29.7	1	590	3	621	1.0e-109	390	COG3519	Type VI protein secretion system component VasA	621
646813943	330	30.18	39	320	44	323	3.0e-45	176	COG3520	Predicted component of the type VI protein secretion system	335
646813944	844	39.62	12	841	2	780	0.0e+00	734	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
646813946	427	19.09	22	424	23	429	1.0e-25	110	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
646813947	149	25.19	1	130	1	135	2.0e-22	98.8	COG3521	Predicted component of the type VI protein secretion system	159
646813948	443	32.28	3	441	5	446	3.0e-90	326	COG3522	Predicted component of the type VI protein secretion system	446
646813949	288	30.42	12	273	3	257	2.0e-46	179	COG3455	Type VI protein secretion system component VasF	262
646813950	1155	23.36	11	1155	12	1187	0.0e+00	480	COG3523	Type VI protein secretion system component VasK	1188
646813951	225	27.94	1	225	6	252	2.0e-34	139	COG0631	Serine/threonine protein phosphatase PrpC	262
646813953	174	41.67	1	168	1	156	2.0e-39	155	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
646813954	968	23.61	48	599	17	550	3.0e-62	234	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
646813955	362	28.51	166	361	54	280	2.0e-12	67.4	COG0790	TPR repeat	292
646813957	844	23.61	48	599	17	550	2.0e-63	237	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
646813964	358	39.12	1	358	1	348	4.0e-85	308	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
646813965	225	42.22	31	161	12	143	9.0e-28	116	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
646813966	280	35.14	9	278	5	268	5.0e-50	191	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
646813967	683	34.55	1	669	1	708	0.0e+00	501	COG0643	Chemotaxis protein histidine kinase CheA	716
646813969	725	45.1	1	720	3	685	0.0e+00	686	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
646813970	223	27.14	15	223	4	210	9.0e-35	140	COG1926	Predicted phosphoribosyltransferase	220
646813971	698	18.38	25	689	55	764	1.0e-47	185	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
646813972	147	24.09	10	145	14	148	3.0e-08	51.3	COG1714	Uncharacterized membrane protein YckC, RDD family	172
646813973	422	44.16	1	422	1	424	0.0e+00	485	COG0151	Phosphoribosylamine-glycine ligase	428
646813974	214	25.12	15	206	27	240	1.0e-19	90.1	COG1587	Uroporphyrinogen-III synthase	248
646813975	527	35.13	1	524	17	553	3.0e-97	349	COG0659	Sulfate permease or related transporter, MFS superfamily	554
646813976	480	41.74	10	476	3	444	5.0e-128	451	COG1160	Predicted GTPases	444
646813977	180	32.71	1	107	1	104	2.0e-12	66	COG1544	Ribosome-associated translation inhibitor RaiA	110
646813979	313	42.24	1	312	4	324	4.0e-81	294	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
646813980	165	41.29	14	165	4	158	3.0e-32	131	COG0440	Acetolactate synthase, small subunit	163
646813981	564	50.36	2	556	1	549	0.0e+00	657	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
646813984	185	29.38	11	185	9	177	7.0e-19	87.2	COG1183	Phosphatidylserine synthase	234
646813985	365	30.68	190	365	9	180	7.0e-35	141	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646813988	250	33.07	4	250	2	241	4.0e-39	155	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
646813990	623	32.43	349	619	113	408	2.0e-31	131	COG0840	Methyl-accepting chemotaxis protein	408
646813992	1188	31.05	526	980	5	461	1.0e-83	305	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646813993	240	57.2	5	237	1	236	4.0e-90	324	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
646813994	258	48.22	1	252	1	250	9.0e-88	316	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
646813995	318	35.86	3	300	5	306	3.0e-43	168	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
646813996	300	42.33	1	299	3	297	4.0e-53	201	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
646813997	373	32.96	22	371	7	361	1.0e-53	203	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646814001	282	16.55	144	282	16	151	3.0e-09	56.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
646814003	262	17.57	43	259	7	206	1.0e-06	47.2	COG0400	Predicted esterase	207
646814004	145	31.19	32	140	5	108	4.0e-16	77.6	COG1416	Intracellular sulfur oxidation protein, DsrE/DsrF family	112
646814006	135	22.38	2	130	4	146	4.0e-09	53.8	COG2143	Thioredoxin-related protein	182
646814007	589	27.41	119	555	51	475	1.0e-52	201	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
646814012	150	30.07	16	150	6	148	1.0e-15	76.2	COG5501	Predicted secreted protein	148
646814016	406	32.92	1	405	3	404	5.0e-90	324	COG0303	Molybdopterin biosynthesis enzyme	404
646814019	374	25.45	1	326	9	316	2.0e-35	143	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
646814020	416	37.47	36	410	51	423	7.0e-72	264	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
646814021	415	21.93	104	395	3	293	9.0e-24	105	COG0501	Zn-dependent protease with chaperone function	302
646814023	122	36.51	1	121	8	133	8.0e-25	105	COG0824	Acyl-CoA thioesterase FadM	137
646814026	570	37.02	1	384	2	384	7.0e-54	205	COG0475	Kef-type K+ transport system, membrane component KefB	397
646814027	382	37.44	1	382	1	384	5.0e-103	368	COG1979	Alcohol dehydrogenase YqhD, Fe-dependent ADH family	384
646814029	847	27.22	415	716	80	405	4.0e-34	140	COG0840	Methyl-accepting chemotaxis protein	408
646814030	339	39.77	1	338	1	315	3.0e-78	285	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
646814031	323	25.86	9	322	2	322	5.0e-27	115	COG1275	Tellurite resistance protein TehA and related permeases	329
646814033	245	21.63	5	244	2	240	4.0e-13	68.7	COG0368	Cobalamin synthase	246
646814034	464	36.65	1	460	1	482	1.0e-113	404	COG1492	Cobyric acid synthase	486
646814035	164	34.27	1	164	1	174	2.0e-30	124	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
646814036	199	32.16	1	197	4	200	1.0e-22	99.9	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
646814037	352	24.59	4	350	8	344	2.0e-36	146	COG2038	NaMN:DMB phosphoribosyltransferase	347
646814038	260	22.84	27	224	37	268	2.0e-16	80	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
646814039	207	25.52	8	188	1	191	2.0e-21	96.2	COG0778	Nitroreductase	207
646814040	344	23.89	24	341	21	353	6.0e-47	181	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
646814041	294	36.59	1	294	4	313	2.0e-68	252	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
646814042	419	30.36	2	415	1	445	2.0e-84	306	COG1797	Cobyrinic acid a,c-diamide synthase	451
646814043	319	31.68	4	318	14	332	3.0e-32	132	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
646814044	232	27.94	1	228	2	247	2.0e-33	136	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
646814045	277	28.36	21	277	53	318	3.0e-27	116	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
646814046	632	20.39	2	632	5	699	3.0e-25	110	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
646814049	207	31.48	1	202	4	217	7.0e-32	130	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
646814050	229	30.74	7	228	4	233	3.0e-44	171	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
646814051	220	20.66	2	220	2	242	2.0e-10	59.4	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
646814052	126	35.25	8	126	15	135	2.0e-22	97.6	COG0848	Biopolymer transport protein ExbD	137
646814055	218	33.92	1	217	1	226	4.0e-39	154	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646814058	154	45.64	1	149	2	149	1.0e-50	192	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
646814059	277	48.94	1	277	5	286	4.0e-96	344	COG0788	Formyltetrahydrofolate hydrolase	287
646814060	419	52.98	6	417	17	421	0.0e+00	512	COG0281	Malic enzyme	432
646814061	223	33.03	15	223	34	249	5.0e-45	174	COG1496	Copper oxidase (laccase) domain	249
646814062	269	32.75	1	267	2	280	5.0e-58	218	COG0169	Shikimate 5-dehydrogenase	283
646814065	181	25.14	7	173	2	179	4.0e-17	81.2	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
646814067	392	34.91	6	392	8	386	3.0e-93	335	COG0754	Glutathionylspermidine synthase	387
646814070	319	29.64	9	314	4	330	1.0e-45	177	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
646814071	378	33.16	1	376	3	373	1.0e-76	280	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
646814072	252	36.84	1	251	3	260	9.0e-61	227	COG0171	NH3-dependent NAD+ synthetase	268
646814077	152	29.73	1	74	1	74	3.0e-09	54.6	COG1826	Sec-independent protein translocase protein TatA	94
646814078	243	43.62	3	242	8	250	1.0e-47	183	COG0805	Sec-independent protein secretion pathway component TatC	255
646814079	345	45.11	9	345	1	343	1.0e-110	393	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
646814080	252	21.48	1	243	12	241	3.0e-17	82.6	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
646814081	226	29.2	10	225	2	226	1.0e-24	106	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646814083	434	23.14	1	374	6	357	4.0e-41	162	COG0348	Polyferredoxin	386
646814084	444	42.89	4	444	9	436	4.0e-86	312	COG0733	Na+-dependent transporter, SNF family	439
646814086	697	23.97	194	444	52	314	2.0e-17	84.8	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
646814087	356	22.03	3	350	4	312	1.0e-13	71.1	COG1397	ADP-ribosylglycohydrolase	314
646814088	159	31.68	2	156	10	169	2.0e-23	101	COG0684	Regulator of RNase E activity RraA	210
646814089	340	40.47	4	336	1	341	2.0e-96	346	COG2008	Threonine aldolase	342
646814090	230	12.74	2	230	21	279	5.0e-11	61.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646814091	136	26.96	2	116	14	121	3.0e-12	64.5	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
646814092	454	36.69	4	439	13	456	2.0e-91	330	COG4865	Glutamate mutase epsilon subunit	485
646814094	525	28.84	6	525	13	530	2.0e-76	280	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
646814095	91	34.65	1	89	1	97	2.0e-11	60.4	COG2863	Cytochrome c553	121
646814096	91	33.66	1	89	1	97	3.0e-07	46.5	COG2863	Cytochrome c553	121
646814097	764	26.07	516	743	8	239	5.0e-47	183	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
646814098	280	31.64	107	279	5	180	3.0e-29	122	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646814100	1027	23.56	5	1022	2	1006	0.0e+00	498	COG0841	Multidrug efflux pump subunit AcrB	1009
646814102	300	44.05	1	299	3	311	1.0e-90	326	COG0275	16S rRNA C1402 N4-methylase RsmH	314
646814103	191	18.18	1	185	3	188	1.0e-08	53.4	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
646814104	91	57.14	1	91	2	92	2.0e-20	91	COG0776	Bacterial nucleoid DNA-binding protein	94
646814106	101	28.12	7	101	10	101	1.0e-10	58.1	COG2863	Cytochrome c553	121
646814109	223	32.89	4	223	2	228	2.0e-42	165	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646814114	175	28	22	174	36	209	2.0e-13	69.3	COG2834	Outer membrane lipoprotein-sorting protein	211
646814115	870	55.3	1	854	1	822	0.0e+00	991	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
646814116	402	33.9	1	402	1	408	2.0e-76	279	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
646814118	362	28.57	23	335	16	341	3.0e-52	199	COG1559	Cell division protein YceG, involved in septum cleavage	342
646814119	730	66.8	1	729	5	739	0.0e+00	1127	COG2838	Monomeric isocitrate dehydrogenase	744
646814120	315	46.3	4	311	1	310	2.0e-90	325	COG0039	Malate/lactate dehydrogenase	313
646814122	353	17.99	5	338	3	299	2.0e-12	67.3	COG1397	ADP-ribosylglycohydrolase	314
646814123	191	52.53	1	191	2	199	7.0e-69	253	COG0605	Superoxide dismutase	204
646814125	385	19.22	1	369	2	372	5.0e-18	85.7	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646814127	292	29.33	1	292	2	278	2.0e-34	139	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
646814129	378	47.89	23	354	10	337	6.0e-86	311	COG0206	Cell division GTPase FtsZ	338
646814130	462	36.91	1	381	4	378	1.0e-77	284	COG0849	Cell division ATPase FtsA	418
646814132	760	25.92	9	759	1	692	9.0e-71	261	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
646814134	115	38.05	4	115	3	115	4.0e-22	96.7	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
646814136	91	51.72	1	87	1	87	3.0e-23	100	COG2257	Type III secretion system substrate exporter, FlhB-like	92
646814138	594	29.32	3	592	15	595	2.0e-102	367	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
646814139	418	28.23	104	407	76	408	1.0e-25	111	COG0840	Methyl-accepting chemotaxis protein	408
646814141	249	26.82	1	249	4	264	3.0e-24	105	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646814142	242	53.33	3	242	10	248	2.0e-68	252	COG1338	Flagellar biosynthetic protein FliP	248
646814143	635	31.72	329	634	80	408	2.0e-35	144	COG0840	Methyl-accepting chemotaxis protein	408
646814145	449	19.01	73	444	62	443	4.0e-30	126	COG1538	Outer membrane protein TolC	457
646814148	153	29.8	1	149	1	148	2.0e-22	98	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
646814149	202	41.9	1	199	2	196	9.0e-47	180	COG0218	GTP-binding protein EngB required for normal cell division	200
646814150	180	27.08	21	162	35	171	1.0e-17	83.1	COG1934	Lipopolysaccharide export system protein LptA	173
646814152	165	46.95	1	164	7	169	4.0e-47	180	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
646814153	190	56.02	1	190	5	195	3.0e-69	254	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
646814154	269	38.12	17	205	13	214	5.0e-45	174	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
646814156	262	49.81	1	256	2	255	1.0e-77	282	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
646814158	442	56.31	1	442	2	444	0.0e+00	555	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
646814159	178	56.74	1	178	1	177	2.0e-66	245	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
646814160	148	45.27	1	148	1	147	2.0e-27	115	COG0359	Ribosomal protein L9	148
646814161	213	22.6	3	204	2	207	9.0e-12	63.6	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
646814162	186	47.87	1	186	3	190	4.0e-63	233	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
646814163	164	56	13	162	3	152	1.0e-54	205	COG0669	Phosphopantetheine adenylyltransferase	159
646814164	188	36.36	1	186	4	201	1.0e-32	132	COG0125	Thymidylate kinase	208
646814165	407	42.52	3	407	1	420	2.0e-119	422	COG0124	Histidyl-tRNA synthetase	429
646814166	601	40.73	1	596	31	652	0.0e+00	651	COG1166	Arginine decarboxylase (spermidine biosynthesis)	652
646814167	254	49.22	20	211	2	194	1.0e-58	219	COG1045	Serine acetyltransferase	194
646814168	244	22.18	1	242	6	253	1.0e-08	53.5	COG0730	Uncharacterized membrane protein YfcA	258
646814169	412	40.53	1	412	29	442	7.0e-99	354	COG0513	Superfamily II DNA and RNA helicase	513
646814170	830	34.18	5	829	7	861	0.0e+00	594	COG1048	Aconitase A	861
646814171	666	25	330	654	11	316	2.0e-29	124	COG0668	Small-conductance mechanosensitive channel	316
646814172	937	56.03	1	937	2	935	0.0e+00	1323	COG0178	Excinuclease UvrABC ATPase subunit	935
646814175	353	26.55	1	329	3	340	1.0e-45	177	COG1253	Hemolysin or related protein, contains CBS domains	429
646814177	208	26.59	3	173	25	196	5.0e-25	107	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
646814179	412	19.9	9	400	16	400	5.0e-10	59.5	COG2223	Nitrate/nitrite transporter NarK	417
646814181	305	22.9	1	287	77	370	2.0e-40	159	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
646814185	282	33.21	10	281	13	284	2.0e-37	149	COG1284	Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains	289
646814186	411	38.59	3	411	1	407	4.0e-83	302	COG1301	Na+/H+-dicarboxylate symporter	415
646814188	319	31.9	4	316	5	322	6.0e-60	224	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
646814190	432	20.35	16	429	23	458	1.0e-20	94.9	COG1113	L-asparagine transporter and related permeases	462
646814192	455	34.07	1	443	2	454	1.0e-101	363	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
646814193	205	37.69	7	204	6	203	6.0e-30	124	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
646814194	96	23.91	5	96	4	95	2.0e-11	60.4	COG1359	Quinol monooxygenase YgiN	100
646814196	194	23.5	1	189	4	203	2.0e-16	79.2	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646814200	198	51.28	1	194	3	194	8.0e-66	243	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
646814203	394	23.72	19	374	49	376	6.0e-24	105	COG5557	Ni/Fe-hydrogenase 2 integral membrane subunit HybB	401
646814204	268	44.1	43	231	1	195	2.0e-51	195	COG0437	Fe-S-cluster-containing dehydrogenase component	203
646814205	576	20.85	253	576	9	327	1.0e-25	111	COG0642	Signal transduction histidine kinase	336
646814206	229	23.68	13	228	1	226	1.0e-27	116	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646814207	72	59.09	6	71	3	66	3.0e-19	86.7	COG1278	Cold shock protein, CspA family	67
646814209	231	23.33	1	202	3	205	2.0e-21	96.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646814213	155	28.86	3	149	4	152	3.0e-21	94.3	COG4087	Soluble P-type ATPase	152
646814214	295	26.47	15	145	2	137	2.0e-06	46.3	COG2510	Uncharacterized membrane protein	140
646814216	198	23.89	11	187	30	209	2.0e-17	82.6	COG3201	Nicotinamide riboside transporter PnuC	222
646814219	457	29.78	8	457	1	458	4.0e-97	348	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
646814222	187	37.5	3	186	57	241	1.0e-37	149	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
646814225	266	28.57	1	266	2	255	1.0e-12	67.3	COG0730	Uncharacterized membrane protein YfcA	258
646814227	841	26.94	6	288	11	305	3.0e-44	174	COG5309	Exo-beta-1,3-glucanase,  GH17 family	305
646814231	209	28.34	24	202	1	183	1.0e-19	90	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
646814233	270	24.02	12	222	23	244	3.0e-17	82.8	COG3782	Uncharacterized protein	289
646814236	229	37.22	4	219	3	224	3.0e-49	188	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646814237	368	28.88	44	362	20	327	1.0e-40	161	COG0642	Signal transduction histidine kinase	336
646814238	754	27.27	384	748	14	408	4.0e-35	143	COG0840	Methyl-accepting chemotaxis protein	408
646814239	248	19.34	7	248	6	242	7.0e-20	91.2	COG3884	Acyl-ACP thioesterase	250
646814248	150	17.76	1	128	16	167	7.0e-11	60.2	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
646814256	97	32.97	8	97	6	96	1.0e-11	61.5	COG1359	Quinol monooxygenase YgiN	100
646814258	511	64.15	195	511	1	315	0.0e+00	518	COG0519	GMP synthase, PP-ATPase domain/subunit	315
646814260	463	22.32	32	452	1	419	3.0e-30	126	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
646814261	483	37.76	4	482	9	495	1.0e-128	453	COG0029	Aspartate oxidase	518
646814263	195	28.57	7	193	5	214	8.0e-29	120	COG1451	Predicted metal-dependent hydrolase	223
646814264	390	43.51	5	388	1	391	8.0e-116	410	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
646814265	294	34.69	1	294	8	299	8.0e-55	207	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
646814266	724	23.33	17	430	21	400	2.0e-38	154	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
646814269	652	39.57	1	548	1	529	1.0e-126	447	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
646814270	147	48.65	1	147	1	148	6.0e-29	119	COG1610	Uncharacterized conserved protein YqeY	148
646814271	418	34.68	240	410	7	178	3.0e-33	136	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646814272	555	23.31	1	555	9	554	8.0e-63	235	COG2831	Hemolysin activation/secretion protein	554
646814275	220	58.38	21	217	1	197	1.0e-81	296	COG0529	Adenylylsulfate kinase or related kinase	197
646814277	795	18.47	219	795	5	577	6.0e-12	66.6	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
646814279	478	35.94	259	467	2	216	9.0e-39	155	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
646814281	228	27.83	5	224	2	228	4.0e-25	108	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646814283	273	27.43	4	233	9	223	3.0e-30	125	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
646814284	571	25.23	29	562	3	484	7.0e-49	188	COG1757	Na+/H+ antiporter NhaC	485
646814285	184	46.24	2	182	3	188	6.0e-29	120	COG1971	Putative Mn2+ efflux pump MntP	190
646814286	266	36.5	1	261	23	285	7.0e-50	190	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
646814287	196	30.57	8	194	2	184	6.0e-37	147	COG0742	16S rRNA G966 N2-methylase RsmD	187
646814289	270	32.1	2	268	13	262	6.0e-47	181	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
646814290	515	48.43	294	515	1	222	1.0e-43	171	COG1418	HD superfamily phosphodieaserase, includes HD domain of RNase Y	222
646814291	178	26.78	6	177	5	183	3.0e-21	95	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
646814292	180	31.43	58	162	25	127	4.0e-07	48	COG0526	Thiol-disulfide isomerase or thioredoxin	127
646814293	310	46.86	10	304	23	340	2.0e-89	322	COG0552	Signal recognition particle GTPase	340
646814295	220	30.57	1	220	1	228	7.0e-35	140	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646814297	307	33.58	16	274	21	266	7.0e-43	167	COG3258	Cytochrome c	293
646814298	113	31.68	11	108	4	102	7.0e-09	52.5	COG1695	DNA-binding transcriptional regulator, PadR family	138
646814300	209	26.92	4	208	3	208	1.0e-20	93.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646814301	154	24.68	1	148	1	149	4.0e-08	50.7	COG0328	Ribonuclease HI	154
646814302	183	33.69	1	181	1	185	4.0e-34	137	COG3150	Predicted esterase YcpF, UPF0227 family	191
646814303	637	28.08	314	637	60	408	4.0e-32	133	COG0840	Methyl-accepting chemotaxis protein	408
646814304	288	21.97	6	288	19	305	3.0e-38	152	COG2017	Galactose mutarotase or related enzyme	308
646814305	145	34.48	1	134	8	152	4.0e-26	110	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
646814308	197	23.79	1	197	1	206	1.0e-15	76.5	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646814310	207	35.61	1	203	1	205	9.0e-30	123	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646814312	449	51.87	1	449	1	453	0.0e+00	572	COG1066	Predicted ATP-dependent serine protease	456
646814313	134	33.86	3	129	1	124	9.0e-21	92.7	COG5496	Predicted thioesterase	130
646814314	139	37.93	1	135	7	151	3.0e-25	107	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
646814315	306	38.89	1	301	10	314	8.0e-39	154	COG0530	Ca2+/Na+ antiporter	320
646814316	134	31.39	1	134	5	141	2.0e-23	101	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
646814317	145	38.3	4	144	16	155	2.0e-30	124	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
646814318	217	41.04	37	209	1	161	6.0e-37	147	COG1592	Rubrerythrin	166
646814320	433	39.1	2	416	9	429	1.0e-66	247	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
646814321	569	35.27	2	566	1	563	1.0e-117	417	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
646814322	353	40.58	50	353	1	310	8.0e-81	294	COG0167	Dihydroorotate dehydrogenase	310
646814323	426	32.71	1	419	10	432	1.0e-79	290	COG0612	Predicted Zn-dependent peptidase	438
646814324	154	27.05	21	140	7	125	2.0e-15	75.3	COG2346	Truncated hemoglobin YjbI	133
646814325	295	46.15	1	295	2	298	4.0e-80	291	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
646814326	259	28.79	5	257	3	251	9.0e-36	143	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646814327	180	35.64	1	179	8	186	3.0e-20	91.6	COG0558	Phosphatidylglycerophosphate synthase	192
646814328	350	37.37	1	349	3	374	2.0e-50	193	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
646814329	226	39.19	9	226	5	224	3.0e-55	208	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
646814332	235	23.11	1	235	6	264	2.0e-10	59.6	COG0428	Zinc transporter ZupT	266
646814333	263	49.61	3	258	1	252	2.0e-77	282	COG0134	Indole-3-glycerol phosphate synthase	254
646814335	127	26.32	12	125	6	106	3.0e-09	54.2	COG0727	Fe-S-cluster containining protein	132
646814336	236	32.33	1	225	18	242	1.0e-36	146	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
646814337	104	39.44	11	81	2	68	6.0e-08	49	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
646814338	376	33.51	3	376	2	361	1.0e-74	273	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
646814339	277	41.7	5	270	4	273	2.0e-76	279	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
646814340	185	32.14	1	183	1	195	8.0e-22	97	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
646814355	196	40.98	1	193	2	205	4.0e-38	151	COG0135	Phosphoribosylanthranilate isomerase	208
646814356	213	54.25	1	212	4	214	4.0e-78	284	COG0036	Pentose-5-phosphate-3-epimerase	220
646814357	336	37.61	109	335	86	314	7.0e-48	184	COG2829	Outer membrane phospholipase A	317
646814360	214	34.51	6	212	2	226	1.0e-34	140	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646814364	518	27.57	323	507	1	181	4.0e-35	142	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646814369	221	34.5	1	221	1	228	1.0e-45	176	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646814370	166	42.33	4	166	3	164	2.0e-34	138	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
646814371	133	40.52	7	122	2	115	2.0e-19	88	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
646814373	149	27.15	1	146	1	148	2.0e-19	88.9	COG2236	Hypoxanthine phosphoribosyltransferase	192
646814374	432	50.35	1	432	7	436	1.0e-101	363	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
646814375	285	33.68	1	285	1	285	3.0e-50	192	COG1578	Uncharacterized conserved protein, contains ATP-grasp and redox domains	285
646814377	225	44.17	20	222	1	204	4.0e-65	241	COG2360	Leu/Phe-tRNA-protein transferase	221
646814378	455	31	8	452	1	455	3.0e-96	346	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
646814381	199	18.24	5	159	8	159	6.0e-18	84.3	COG3467	Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily	166
646814383	189	35.14	2	172	1	184	6.0e-31	127	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
646814384	259	41.18	1	253	2	248	4.0e-63	234	COG1010	Precorrin-3B methylase	249
646814385	338	28.26	17	338	7	298	4.0e-30	125	COG2073	Cobalamin biosynthesis protein CbiG	298
646814386	247	45.83	1	234	4	242	5.0e-72	263	COG2875	Precorrin-4 methylase	254
646814387	390	32.8	207	386	6	186	2.0e-21	97.2	COG2242	Precorrin-6B methylase 2	187
646814388	340	32.68	34	333	64	347	8.0e-52	197	COG1903	Cobalamin biosynthesis protein CbiD	367
646814390	236	32.85	13	219	8	201	6.0e-32	131	COG2082	Precorrin isomerase	210
646814392	272	22.1	11	269	3	259	8.0e-18	84.2	COG4822	Cobalamin biosynthesis protein CbiK, Co2+ chelatase	265
646814395	273	25.9	1	267	1	268	1.0e-28	120	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
646814396	356	43.75	7	352	2	352	4.0e-109	388	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
646814397	274	25.28	2	263	5	267	8.0e-33	134	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
646814398	273	30.86	1	265	4	266	1.0e-34	140	COG0555	ABC-type sulfate transport system, permease component	274
646814399	340	28.09	48	340	2	297	1.0e-42	167	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
646814400	336	37.43	4	333	2	333	1.0e-76	279	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
646814401	1124	36.47	952	1121	16	181	6.0e-41	163	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646814402	276	32.93	118	274	2	168	9.0e-32	130	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
646814403	164	26.61	43	144	16	124	3.0e-07	48.4	COG0526	Thiol-disulfide isomerase or thioredoxin	127
646814404	328	32.35	223	324	22	123	7.0e-20	91.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646814405	697	24.28	1	572	10	529	2.0e-73	271	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
646814407	1557	35.42	8	904	4	883	0.0e+00	696	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
646814408	1132	30.54	271	933	4	642	1.0e-117	418	COG1020	Non-ribosomal peptide synthetase component F	642
646814409	3238	37.5	10	982	3	988	0.0e+00	830	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
646814410	247	38.81	15	232	3	220	4.0e-62	231	COG3208	Surfactin synthase thioesterase subunit	244
646814411	453	29.11	55	417	13	322	9.0e-47	181	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646814412	230	28.33	7	185	1	180	8.0e-25	107	COG2091	Phosphopantetheinyl transferase	223
646814413	694	20.75	25	694	49	768	6.0e-47	182	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
646814416	765	24.06	5	765	3	725	2.0e-72	267	COG1033	Predicted exporter protein, RND superfamily	727
646814417	754	29.51	16	522	1	472	2.0e-96	347	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
646814421	562	30.8	45	562	22	488	7.0e-82	298	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
646814427	302	29.49	1	282	6	296	2.0e-45	176	COG0731	Wyosine [tRNA(Phe)-imidazoG37] synthetase, radical SAM superfamily	296
646814428	343	45.95	1	343	6	351	2.0e-108	386	COG0407	Uroporphyrinogen-III decarboxylase	352
646814429	179	27.88	10	173	3	156	5.0e-19	87.6	COG2862	Uncharacterized membrane protein YqhA	169
646814430	345	47.79	4	339	2	334	1.0e-102	366	COG0136	Aspartate-semialdehyde dehydrogenase	334
646814431	856	56.12	7	812	5	804	0.0e+00	968	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
646814432	73	43.06	1	70	1	72	1.0e-07	48.4	COG2841	Uncharacterized conserved protein YdcH, DUF465 family	72
646814433	393	43.39	7	393	8	404	2.0e-102	366	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
646814434	376	23.66	138	360	3	215	2.0e-13	70.3	COG0569	Trk K+ transport system, NAD-binding component	225
646814435	62	62.9	1	61	1	62	7.0e-13	65.7	COG0227	Ribosomal protein L28	77
646814437	308	31.45	1	306	2	326	5.0e-45	175	COG0859	ADP-heptose:LPS heptosyltransferase	334
646814438	346	24.13	70	346	102	379	1.0e-22	100	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646814440	362	18.88	29	354	5	332	2.0e-18	87.4	COG0859	ADP-heptose:LPS heptosyltransferase	334
646814441	163	28	4	149	13	162	4.0e-12	64.5	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
646814442	369	25.89	33	362	3	326	5.0e-33	135	COG0859	ADP-heptose:LPS heptosyltransferase	334
646814443	317	26.97	7	296	2	296	3.0e-33	135	COG0859	ADP-heptose:LPS heptosyltransferase	334
646814445	354	30.59	21	353	50	380	8.0e-31	128	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646814446	368	25.97	6	365	1	333	2.0e-39	157	COG0859	ADP-heptose:LPS heptosyltransferase	334
646814447	237	18.65	7	237	4	253	1.0e-11	63.6	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
646814448	296	27.24	14	290	26	299	3.0e-51	195	COG1560	Lauroyl/myristoyl acyltransferase	308
646814449	336	26.98	4	334	1	330	4.0e-47	182	COG0859	ADP-heptose:LPS heptosyltransferase	334
646814450	489	31.46	1	434	1	440	9.0e-80	291	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
646814452	457	40.58	20	457	2	451	6.0e-112	398	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
646814453	1478	53.48	698	1182	2	485	0.0e+00	589	COG0069	Glutamate synthase domain 2	485
646814454	341	40.92	12	335	7	324	3.0e-90	325	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
646814455	351	41.8	42	351	27	330	4.0e-87	315	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
646814456	208	30.86	1	175	3	173	2.0e-22	98.9	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
646814457	427	47.62	47	424	1	378	1.0e-91	330	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
646814459	227	24.44	14	226	3	226	5.0e-23	101	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646814461	291	19.02	9	287	23	317	7.0e-10	58.1	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
646814462	434	38.37	1	434	28	465	2.0e-99	356	COG0513	Superfamily II DNA and RNA helicase	513
646814465	641	23.48	199	641	178	647	1.0e-52	201	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
646814468	187	32.99	1	187	1	183	2.0e-26	112	COG0693	Putative intracellular protease/amidase	188
646814469	243	27.76	5	243	1	244	6.0e-36	144	COG1414	DNA-binding transcriptional regulator, IclR family	246
646814471	136	38.03	1	135	5	140	5.0e-24	103	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
646814472	310	30.49	1	300	1	291	4.0e-58	218	COG1230	Co/Zn/Cd efflux system component	296
646814473	321	27.94	8	313	13	314	2.0e-47	183	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
646814475	416	39.2	14	413	20	440	3.0e-77	282	COG2233	Xanthine/uracil permease	451
646814476	207	49.75	9	205	11	209	1.0e-57	216	COG0035	Uracil phosphoribosyltransferase	210
646814477	286	47.6	1	245	1	248	5.0e-62	231	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
646814479	377	36.89	8	373	2	340	1.0e-83	303	COG1566	Multidrug resistance efflux pump	352
646814480	495	32.54	64	484	34	450	8.0e-71	261	COG1538	Outer membrane protein TolC	457
646814481	202	21.29	1	202	6	198	2.0e-12	65.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646814487	228	37.72	2	228	13	234	1.0e-51	196	COG0284	Orotidine-5'-phosphate decarboxylase	240
646814488	132	36.69	1	132	7	145	5.0e-24	103	COG0781	Transcription termination factor NusB	151
646814489	156	55.56	1	153	1	152	1.0e-48	185	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
646814490	266	58.02	1	260	18	268	8.0e-99	353	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
646814491	563	20.66	289	529	2	210	6.0e-16	79.5	COG0569	Trk K+ transport system, NAD-binding component	225
646814495	421	57.21	1	421	1	420	0.0e+00	560	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
646814498	290	31.13	6	111	15	119	1.0e-18	87.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646814501	193	33.5	1	193	4	199	3.0e-34	138	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
646814502	240	37.76	1	235	3	242	9.0e-54	203	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
646814503	275	32.88	3	272	11	304	2.0e-50	192	COG0196	FAD synthase	304
646814504	236	22.33	18	217	11	218	1.0e-08	53.7	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
646814505	168	46.99	1	166	3	156	4.0e-54	204	COG1225	Peroxiredoxin	157
646814507	462	41.83	9	460	1	455	2.0e-104	373	COG0277	FAD/FMN-containing dehydrogenase	459
646814508	263	20.51	1	249	9	281	1.0e-17	83.8	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
646814511	381	20.71	1	362	1	305	3.0e-31	129	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
646814515	382	23.24	1	380	2	410	7.0e-46	178	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
646814517	387	17.35	1	377	3	388	3.0e-11	63.1	COG1668	ABC-type Na+ efflux pump, permease component	407
646814518	286	35.74	1	282	3	293	3.0e-61	228	COG1131	ABC-type multidrug transport system, ATPase component	293
646814519	405	20.68	57	402	143	512	2.0e-25	110	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
646814523	234	32.54	1	233	3	251	3.0e-43	168	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646814524	506	32.49	1	506	2	497	1.0e-107	384	COG2986	Histidine ammonia-lyase	498
646814525	286	20.95	5	284	9	300	2.0e-19	89.6	COG4261	Predicted acyltransferase, LPLAT superfamily	309
646814526	234	22.78	5	232	4	233	5.0e-09	54.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
646814529	371	34.01	15	368	13	409	7.0e-70	257	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
646814539	231	40.95	1	229	2	233	5.0e-50	190	COG0775	Nucleoside phosphorylase	234
646814540	309	44.66	1	304	1	308	3.0e-80	291	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
646814541	191	39.55	3	177	7	174	8.0e-33	133	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
646814542	331	19.63	115	330	67	261	1.0e-07	51.2	COG1729	Periplasmic TolA-binding protein (function unknown)	262
646814543	180	26.6	1	180	6	189	1.0e-25	109	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
646814544	422	23.72	1	422	1	421	3.0e-49	189	COG0823	Periplasmic component of the Tol biopolymer transport system	425
646814546	129	38.52	6	127	12	132	1.0e-22	98.7	COG0848	Biopolymer transport protein ExbD	137
646814548	125	34.71	1	119	1	121	1.0e-21	95.3	COG0355	FoF1-type ATP synthase, epsilon subunit	135
646814549	464	73.23	1	464	2	466	0.0e+00	802	COG0055	FoF1-type ATP synthase, beta subunit	468
646814550	294	39.25	5	294	1	287	7.0e-74	270	COG0224	FoF1-type ATP synthase, gamma subunit	287
646814551	505	68.86	4	504	2	502	0.0e+00	797	COG0056	FoF1-type ATP synthase, alpha subunit	504
646814552	176	27.27	1	140	3	145	7.0e-11	60.6	COG0712	FoF1-type ATP synthase, delta subunit	178
646814554	140	23.36	1	137	1	137	7.0e-09	53.3	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
646814555	293	34.38	33	285	2	240	7.0e-29	121	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
646814556	259	43.24	2	258	1	251	9.0e-55	206	COG1192	Cellulose biosynthesis protein BcsQ	259
646814557	211	28.33	6	176	1	174	1.0e-24	106	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
646814558	297	25.33	1	296	5	307	2.0e-20	93.4	COG0679	Predicted permease	311
646814560	306	40.91	4	303	3	307	6.0e-88	317	COG0223	Methionyl-tRNA formyltransferase	307
646814562	363	45.21	1	363	2	336	4.0e-115	408	COG0536	GTPase involved in cell partioning and DNA repair	369
646814563	84	72.29	1	83	1	83	2.0e-30	124	COG0211	Ribosomal protein L27	87
646814564	105	44.86	1	105	1	103	1.0e-20	91.4	COG0261	Ribosomal protein L21	103
646814565	129	49.61	1	125	4	130	1.0e-33	135	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
646814566	545	32.43	1	542	1	549	1.0e-95	344	COG0358	DNA primase (bacterial type)	568
646814568	148	55.41	1	145	1	148	3.0e-46	177	COG0328	Ribonuclease HI	154
646814569	223	47.35	1	222	5	230	4.0e-63	234	COG0571	dsRNA-specific ribonuclease	235
646814570	357	52.07	1	356	2	364	0.0e+00	460	COG0082	Chorismate synthase	369
646814571	196	36.84	1	93	1	95	5.0e-17	81.1	COG1342	Predicted DNA-binding protein, UPF0251 family	99
646814572	284	29.79	4	284	27	302	3.0e-37	149	COG0501	Zn-dependent protease with chaperone function	302
646814573	159	31.17	1	151	1	154	2.0e-25	108	COG2062	Phosphohistidine phosphatase SixA	163
646814574	412	32.11	1	408	1	401	2.0e-90	326	COG2081	Predicted flavoprotein YhiN	408
646814575	447	45.61	1	447	1	454	4.0e-128	451	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
646814576	286	23.6	121	268	48	206	3.0e-06	46	COG1847	Predicted RNA-binding protein Jag, conains KH and R3H domains	208
646814577	548	49.62	294	548	53	313	9.0e-66	244	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
646814578	110	45.59	1	68	6	73	9.0e-20	88.9	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
646814579	111	27.68	4	111	1	112	8.0e-13	65.7	COG0594	RNase P protein component	117
646814581	857	50.06	7	857	1	783	0.0e+00	870	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
646814582	178	39.89	1	173	1	183	2.0e-48	185	COG0164	Ribonuclease HII	199
646814585	104	27.72	1	100	1	100	1.0e-12	65.2	COG0011	Uncharacterized conserved protein YqgV, UPF0045/DUF77 family	100
646814586	478	36.67	298	475	1	179	7.0e-39	155	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646814589	283	51.9	123	277	4	160	1.0e-50	193	COG0225	Peptide methionine sulfoxide reductase MsrA	174
646814590	204	35.71	13	189	59	252	5.0e-42	164	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
646814591	153	36.97	29	147	9	126	3.0e-10	58	COG1846	DNA-binding transcriptional regulator, MarR family	126
646814592	181	51.38	1	181	3	160	2.0e-55	208	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
646814593	143	44.62	16	143	11	140	9.0e-13	66.2	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
646814594	114	31.25	5	113	3	112	7.0e-08	49.1	COG3370	Uncharacterized protein	113
646814596	421	39.64	1	421	3	446	0.0e+00	489	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
646814597	863	21.92	2	323	8	333	2.0e-28	121	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
646814599	730	30.33	416	719	76	408	7.0e-28	119	COG0840	Methyl-accepting chemotaxis protein	408
646814600	393	24.32	1	378	3	379	2.0e-36	147	COG1252	NADH dehydrogenase, FAD-containing subunit	405
646814602	665	49.46	2	554	3	537	0.0e+00	595	COG1292	Choline-glycine betaine transporter	537
646814603	152	40.26	1	151	1	154	1.0e-42	165	COG2153	Predicted N-acyltransferase, GNAT family	155
646814604	446	37.78	1	445	2	442	2.0e-69	256	COG2610	H+/gluconate symporter or related permease	442
646814605	342	28.42	249	341	28	122	2.0e-13	70.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646814606	139	26.21	1	139	5	149	6.0e-12	63.3	COG1981	Uncharacterized membrane protein	149
646814608	121	32.47	32	106	15	91	2.0e-10	58	COG0607	Rhodanese-related sulfurtransferase	110
646814609	510	48.06	1	510	3	515	0.0e+00	605	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
646814610	605	35.82	1	386	1	397	2.0e-94	339	COG0004	Ammonia channel protein AmtB	409
646814611	330	21.61	20	314	19	316	9.0e-21	94.6	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
646814612	236	33.18	1	221	1	219	6.0e-30	124	COG2836	Sulfite exporter TauE/SafE	232
646814613	736	45.61	3	726	11	743	0.0e+00	829	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
646814614	320	26.23	16	319	11	297	5.0e-39	155	COG3034	Murein L,D-transpeptidase YafK	298
646814615	389	34.45	134	339	57	262	8.0e-31	128	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
646814616	451	35.96	9	451	18	448	2.0e-85	310	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
646814618	190	62.64	3	184	11	192	2.0e-76	278	COG0302	GTP cyclohydrolase I	195
646814619	398	26.84	3	396	5	396	1.0e-57	217	COG1459	Type II secretory pathway, component PulF	397
646814620	450	42.82	90	450	118	499	2.0e-117	416	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
646814623	293	41.22	1	293	3	298	4.0e-80	291	COG1159	GTPase Era, involved in 16S rRNA processing	298
646814624	502	39.04	13	502	1	487	0.0e+00	487	COG0606	Predicted ATPase with chaperone activity	490
646814625	170	42.6	1	168	2	168	6.0e-47	179	COG0242	Peptide deformylase	168
646814626	194	68.04	1	194	1	194	8.0e-83	299	COG0740	ATP-dependent protease ClpP, protease subunit	200
646814627	433	36.34	1	430	1	423	5.0e-72	265	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
646814629	374	44.21	104	345	31	269	3.0e-75	275	COG2326	Polyphosphate kinase 2, PPK2 family	270
646814630	307	54.55	15	275	6	269	2.0e-91	329	COG2326	Polyphosphate kinase 2, PPK2 family	270
646814631	378	27.49	9	356	23	393	2.0e-72	266	COG0019	Diaminopimelate decarboxylase	394
646814632	54	58.82	1	51	1	51	2.0e-13	67.2	COG1773	Rubredoxin	55
646814633	397	46.13	1	397	1	381	2.0e-115	409	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
646814634	200	27.84	2	185	1	192	9.0e-27	113	COG0625	Glutathione S-transferase	211
646814638	314	25.73	3	279	7	310	9.0e-26	111	COG3621	Patatin-like phospholipase/acyl hydrolase	394
646814642	60	44.9	4	52	13	61	1.0e-10	58	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
646814643	429	19.61	50	383	20	361	8.0e-17	82	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
646814645	637	35.06	464	633	4	177	4.0e-37	150	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646814646	480	40.99	1	476	29	507	2.0e-113	403	COG0513	Superfamily II DNA and RNA helicase	513
646814652	113	49.07	1	108	1	99	2.0e-23	100	COG4378	Uncharacterized protein	103
646814653	148	43.97	8	148	2	140	6.0e-35	140	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
646814654	78	38.67	1	75	1	75	3.0e-11	60.2	COG1918	Fe2+ transport system protein FeoA	75
646814655	706	41.54	8	705	2	652	0.0e+00	645	COG0370	Fe2+ transport system protein B	653
646814657	245	33.19	10	231	13	238	2.0e-47	182	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
646814658	246	39.44	2	246	17	265	8.0e-60	223	COG0159	Tryptophan synthase alpha chain	265
646814659	119	21.93	1	112	1	110	4.0e-07	47.2	COG1943	REP element-mobilizing transposase RayT	136
646814662	269	51.71	10	269	1	263	2.0e-91	329	COG0413	Ketopantoate hydroxymethyltransferase	268
646814663	338	60.84	2	332	1	331	0.0e+00	475	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
646814664	355	20.23	1	347	12	351	3.0e-16	79.6	COG0628	Predicted PurR-regulated permease PerM	355
646814667	246	35.05	145	241	6	102	2.0e-13	69.2	COG0607	Rhodanese-related sulfurtransferase	110
646814669	743	43.59	1	742	1	785	0.0e+00	785	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
646814670	99	47.06	15	99	23	107	4.0e-24	102	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
646814671	211	31.02	11	194	3	186	5.0e-37	147	COG0132	Dethiobiotin synthetase	223
646814672	458	28.14	1	452	1	444	4.0e-76	279	COG0527	Aspartokinase	447
646814674	426	33.33	5	414	24	446	1.0e-105	376	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
646814680	703	44.56	9	702	19	694	0.0e+00	672	COG1298	Flagellar biosynthesis pathway, component FlhA	696
646814681	372	19.35	3	371	6	357	6.0e-15	75.5	COG1344	Flagellin and related hook-associated protein FlgL	360
646814682	435	50.47	1	429	6	434	0.0e+00	541	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
646814684	350	41.76	2	350	4	355	3.0e-93	335	COG1377	Flagellar biosynthesis protein FlhB	363
646814685	249	24.7	4	249	3	248	1.0e-20	94.1	COG1684	Flagellar biosynthesis protein FliR	258
646814687	153	44.08	1	152	1	137	3.0e-39	154	COG1558	Flagellar basal body rod protein FlgC	137
646814688	100	32	1	100	9	105	3.0e-09	53.4	COG1677	Flagellar hook-basal body complex protein FliE	105
646814690	274	27.6	27	271	2	241	4.0e-31	128	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
646814691	386	32.49	1	379	1	393	3.0e-63	235	COG1419	Flagellar biosynthesis GTPase FlhF	407
646814695	256	25.41	1	235	1	240	7.0e-30	124	COG1360	Flagellar motor protein MotB	244
646814696	251	31.11	1	225	1	225	2.0e-39	156	COG1291	Flagellar motor component MotA	266
646814705	223	17.55	47	223	43	228	6.0e-09	54.6	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
646814706	334	34.06	10	330	8	330	5.0e-55	208	COG1536	Flagellar motor switch protein FliG	339
646814707	580	28.57	1	569	9	545	3.0e-74	273	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
646814708	135	35.07	1	132	2	133	8.0e-20	89.6	COG1815	Flagellar basal body rod protein FlgB	133
646814709	241	30.37	1	239	1	265	3.0e-38	151	COG4786	Flagellar basal body rod protein FlgG	265
646814712	263	50.94	1	261	1	264	1.0e-78	286	COG4786	Flagellar basal body rod protein FlgG	265
646814715	175	27.93	2	173	5	174	4.0e-24	104	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
646814716	79	26.32	2	77	1	75	1.0e-11	61.7	COG1837	Predicted RNA-binding protein YlqC, contains KH domain, UPF0109 family	76
646814717	76	56.16	1	72	1	73	5.0e-23	99.2	COG0228	Ribosomal protein S16	87
646814718	451	46.37	1	448	1	451	0.0e+00	483	COG0541	Signal recognition particle GTPase	451
646814719	249	31.76	5	226	14	267	3.0e-40	158	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
646814720	239	28.51	1	235	2	236	2.0e-30	125	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
646814721	250	32.81	1	241	1	250	8.0e-48	183	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
646814722	293	69.12	1	285	4	288	0.0e+00	512	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
646814723	164	54.6	1	163	2	162	8.0e-47	179	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
646814724	1177	29.19	676	1177	62	526	8.0e-72	266	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
646814725	295	44.56	2	295	3	293	8.0e-63	233	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
646814726	470	33.19	18	466	4	440	5.0e-86	311	COG3182	Uncharacterized iron-regulated membrane protein	442
646814728	114	28.7	5	109	4	103	4.0e-11	59.9	COG2105	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family	120
646814730	699	24.16	23	699	44	719	9.0e-55	209	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
646814731	284	34.27	1	282	1	286	2.0e-63	235	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
646814732	637	48.87	1	637	1	663	0.0e+00	783	COG0021	Transketolase	663
646814736	478	15.17	68	469	40	372	8.0e-12	65.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646814737	720	34.85	10	710	1	694	0.0e+00	544	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
646814738	604	16.9	18	432	40	455	7.0e-34	139	COG1538	Outer membrane protein TolC	457
646814739	244	25.22	24	239	3	224	1.0e-23	103	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646814740	488	16.59	17	433	38	455	2.0e-31	130	COG1538	Outer membrane protein TolC	457
646814741	816	25.89	7	816	7	726	1.0e-94	341	COG1033	Predicted exporter protein, RND superfamily	727
646814742	196	26.46	6	187	7	195	2.0e-23	101	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
646814743	245	38.78	1	245	1	229	2.0e-56	212	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
646814744	576	37.75	1	576	2	583	0.0e+00	497	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
646814745	320	28.89	1	297	7	317	5.0e-27	115	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
646814746	286	23.34	2	284	1	308	1.0e-28	120	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646814747	370	23.35	18	370	22	378	2.0e-25	110	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646814748	632	29.59	1	607	1	520	2.0e-91	330	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
646814750	375	24.68	1	375	1	376	7.0e-28	118	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646814751	564	27.46	3	564	127	688	3.0e-73	269	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
646814752	602	29.05	1	584	1	519	8.0e-86	311	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
646814755	396	21.89	1	396	1	380	2.0e-18	87.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646814757	311	21.2	2	303	1	306	2.0e-35	143	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646814760	327	22.05	7	323	1	310	6.0e-34	138	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646814762	362	41.67	17	362	16	373	8.0e-100	357	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
646814764	335	60.12	2	331	1	317	0.0e+00	469	COG1088	dTDP-D-glucose 4,6-dehydratase	340
646814765	189	46.07	1	178	1	173	2.0e-46	178	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
646814766	293	54.11	1	292	1	286	3.0e-104	371	COG1209	dTDP-glucose pyrophosphorylase	286
646814767	358	20.83	61	349	17	316	6.0e-17	82	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
646814769	666	28.43	1	624	1	502	8.0e-86	311	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
646814770	396	35.61	1	396	2	372	1.0e-96	346	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
646814771	327	32.08	9	319	2	307	5.0e-53	201	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646814772	377	38.73	3	374	1	364	3.0e-104	372	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
646814775	415	40.24	1	411	8	426	1.0e-120	426	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
646814776	373	28.89	18	367	1	311	5.0e-55	208	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646814778	405	39.63	1	404	1	414	6.0e-119	421	COG1004	UDP-glucose 6-dehydrogenase	414
646814780	339	54.55	1	329	1	321	2.0e-122	432	COG1087	UDP-glucose 4-epimerase	329
646814784	562	53.16	1	561	11	573	0.0e+00	713	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
646814785	480	44.03	31	380	14	344	2.0e-69	256	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
646814786	219	36.32	1	217	5	225	7.0e-44	170	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646814787	406	20.53	102	385	7	307	9.0e-21	94.9	COG0642	Signal transduction histidine kinase	336
646814788	425	39.89	1	354	4	335	1.0e-87	317	COG0826	Collagenase-like protease, PrtC family	347
646814789	511	27.91	1	509	1	553	3.0e-80	292	COG0497	DNA repair ATPase RecN	557
646814790	288	39.86	14	288	1	281	2.0e-66	246	COG0061	NAD kinase	281
646814791	446	16.33	41	437	45	372	2.0e-07	50.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646814792	717	32.23	19	709	12	695	0.0e+00	549	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
646814793	684	16.95	21	420	44	447	9.0e-35	142	COG1538	Outer membrane protein TolC	457
646814794	702	65.44	1	702	1	693	0.0e+00	973	COG0480	Translation elongation factor EF-G, a GTPase	697
646814795	155	63.51	1	148	1	148	2.0e-49	188	COG0049	Ribosomal protein S7	148
646814796	127	73.98	1	123	7	129	9.0e-47	178	COG0048	Ribosomal protein S12	129
646814797	707	27.23	331	704	5	408	5.0e-32	133	COG0840	Methyl-accepting chemotaxis protein	408
646814798	386	35.86	1	380	11	390	2.0e-65	242	COG2814	Predicted arabinose efflux permease, MFS family	394
646814799	256	21.53	4	253	12	282	2.0e-21	96.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646814804	209	39.42	3	209	2	208	5.0e-32	131	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646814805	149	40.54	1	148	2	147	7.0e-36	143	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
646814806	64	67.21	4	64	3	63	4.0e-16	76.2	COG4895	Uncharacterized protein YwbE	63
646814809	299	51.97	11	286	23	298	9.0e-99	353	COG0320	Lipoate synthase	306
646814810	254	25.79	14	250	10	239	2.0e-22	99.3	COG0095	Lipoate-protein ligase A	248
646814811	894	69.04	10	894	6	887	0.0e+00	1413	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
646814812	573	41.49	148	573	2	403	1.0e-92	333	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
646814813	588	48.35	119	570	7	454	4.0e-128	452	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
646814815	172	21.32	10	168	11	204	3.0e-09	54.9	COG2755	Lysophospholipase L1 or related esterase	216
646814816	215	35.47	15	213	15	217	4.0e-44	171	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
646814817	215	22.22	6	208	20	244	7.0e-09	54.2	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
646814819	199	28.5	1	196	1	203	4.0e-13	68	COG0310	ABC-type Co2+ transport system, permease component	204
646814820	242	26.32	2	241	5	263	1.0e-26	113	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
646814821	95	38.27	1	80	1	81	7.0e-11	58.8	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
646814823	1508	46.55	25	842	8	808	0.0e+00	809	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
646814825	123	61.29	1	123	1	124	4.0e-23	100	COG0222	Ribosomal protein L7/L12	124
646814826	162	39.38	1	157	3	162	2.0e-29	121	COG0244	Ribosomal protein L10	175
646814827	233	59.29	1	224	1	226	3.0e-74	271	COG0081	Ribosomal protein L1	228
646814828	141	60.43	2	140	1	139	1.0e-47	182	COG0080	Ribosomal protein L11	141
646814829	175	45.76	1	174	1	177	4.0e-38	150	COG0250	Transcription antitermination factor NusG	178
646814832	55	52.08	5	52	3	50	7.0e-10	55.6	COG0267	Ribosomal protein L33	50
646814833	402	76.12	1	402	1	394	0.0e+00	670	COG0050	Translation elongation factor EF-Tu, a GTPase	394
646814838	384	33.26	2	384	10	447	7.0e-77	281	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
646814839	353	38.58	23	353	7	316	9.0e-49	187	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
646814840	491	48.2	1	486	2	501	0.0e+00	585	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
646814841	232	34.62	20	222	23	256	2.0e-51	195	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
646814842	694	31.06	2	693	14	648	0.0e+00	486	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
646814843	475	42.92	9	475	4	443	0.0e+00	473	COG0174	Glutamine synthetase	443
646814844	260	26.09	1	251	1	224	2.0e-27	116	COG1387	Histidinol phosphatase or related hydrolase of the PHP family	237
646814845	150	26.06	11	147	10	148	4.0e-24	104	COG0314	Molybdopterin synthase catalytic subunit	149
646814846	73	26.19	1	73	1	84	1.0e-05	41.8	COG1977	Molybdopterin converting factor, small subunit	84
646814847	218	28.81	7	216	1	243	1.0e-29	123	COG1427	Predicted periplasmic solute-binding protein	252
646814848	255	41.42	1	254	4	267	1.0e-53	203	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
646814849	344	32.69	3	344	1	357	2.0e-56	213	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
646814850	400	32.23	12	400	15	378	1.0e-53	203	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
646814851	619	26.71	1	618	3	599	9.0e-77	281	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
646814852	171	48.59	23	161	1	138	2.0e-40	158	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
646814862	189	57.14	1	189	3	190	3.0e-76	277	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
646814863	335	25.89	36	335	1	299	2.0e-40	159	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
646814864	525	24.19	7	519	12	528	5.0e-70	259	COG1178	ABC-type Fe3+ transport system, permease component	540
646814865	329	34.67	1	325	3	348	5.0e-81	294	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
646814867	603	37.47	1	449	6	443	4.0e-124	438	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
646814868	382	39.53	2	379	4	382	6.0e-119	421	COG1168	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	388
646814869	120	45	1	120	4	121	8.0e-21	92.6	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
646814870	171	52.33	1	171	9	179	7.0e-60	223	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
646814871	544	43.41	158	544	12	398	3.0e-124	439	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
646814872	158	43.87	2	156	1	155	9.0e-46	176	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
646814873	423	47.23	7	420	9	421	0.0e+00	478	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
646814874	428	50.25	28	428	1	379	2.0e-115	409	COG0372	Citrate synthase	390
646814876	427	38.71	4	313	9	295	1.0e-59	224	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
646814877	170	34.67	14	163	7	140	1.0e-24	106	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
646814878	171	39.26	4	165	6	166	4.0e-16	78	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
646814879	103	41.41	1	99	1	99	1.0e-17	81.3	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
646814880	629	37.04	6	622	1	606	5.0e-113	401	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
646814881	493	38.22	6	484	6	484	2.0e-97	350	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
646814882	500	30.9	1	466	2	456	8.0e-68	251	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
646814883	263	19.23	16	145	12	132	1.0e-08	54.2	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
646814884	661	43.7	1	591	2	562	0.0e+00	526	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
646814885	243	37.18	7	240	1	228	1.0e-62	232	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
646814899	149	40.43	10	149	2	141	2.0e-23	101	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
646814905	704	39.43	156	700	158	706	0.0e+00	468	COG2217	Cation transport ATPase	713
646814909	166	34.32	1	165	2	151	1.0e-23	102	COG0716	Flavodoxin	151
646814911	390	51.55	1	386	1	385	0.0e+00	464	COG0045	Succinyl-CoA synthetase, beta subunit	387
646814912	290	65.28	1	287	1	288	2.0e-111	395	COG0074	Succinyl-CoA synthetase, alpha subunit	293
646814913	244	22.98	3	223	11	231	5.0e-21	94.7	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
646814914	702	43.37	1	702	7	728	0.0e+00	630	COG2183	Transcriptional accessory protein Tex/SPT6	780
646814915	288	38.26	32	288	9	267	3.0e-58	218	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
646814916	124	27.19	4	114	15	127	3.0e-15	73.8	COG1607	Acyl-CoA hydrolase	157
646814918	275	29.21	1	272	1	289	5.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
646814919	394	17.57	24	389	22	388	3.0e-10	60.2	COG2814	Predicted arabinose efflux permease, MFS family	394
646814920	71	35.82	1	67	1	65	1.0e-10	58.4	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
646814922	167	34.87	2	145	1	152	2.0e-29	121	COG0262	Dihydrofolate reductase	167
646814923	287	60.76	1	287	3	268	5.0e-110	390	COG0207	Thymidylate synthase	268
646814924	205	38.19	3	201	2	200	4.0e-41	161	COG1279	Arginine exporter protein ArgO	202
646814925	209	32.84	1	201	1	196	1.0e-23	103	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
646814926	321	44.39	116	318	18	222	2.0e-59	222	COG0765	ABC-type amino acid transport system, permease component	222
646814927	271	34.66	1	268	3	270	5.0e-33	135	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646814928	245	62.5	4	243	2	240	2.0e-108	385	COG1126	ABC-type polar amino acid transport system, ATPase component	240
646814930	598	26.82	1	444	1	465	7.0e-86	311	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
646814931	538	29.91	9	525	16	540	2.0e-67	250	COG0747	ABC-type transport system, periplasmic component	556
646814932	340	44.07	8	336	5	313	6.0e-74	271	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
646814933	281	47.46	6	280	12	287	1.0e-70	260	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
646814934	569	44.68	1	564	2	539	0.0e+00	615	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
646814935	226	27.56	10	224	3	225	2.0e-20	92.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646814936	567	22.16	13	317	18	345	4.0e-19	90.1	COG3614	Extracellular (periplasmic) sensor domain CHASE1 (specificity unknown)	348
646814937	702	42.42	1	589	2	584	0.0e+00	570	COG0514	Superfamily II DNA helicase RecQ	590
646814939	348	40.68	175	347	4	180	8.0e-42	164	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646814941	117	31.13	1	106	1	106	5.0e-21	93.2	COG1733	DNA-binding transcriptional regulator, HxlR family	120
646814942	275	31.58	124	274	4	153	1.0e-21	96.8	COG3449	DNA gyrase inhibitor GyrI	154
646814943	306	40.73	6	306	12	313	4.0e-63	235	COG0385	Predicted Na+-dependent transporter	319
646814944	303	40.67	5	303	11	310	3.0e-58	218	COG0385	Predicted Na+-dependent transporter	319
646814945	210	46.04	10	210	3	203	3.0e-65	241	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
646814946	181	27.43	1	150	4	178	5.0e-23	100	COG1335	Nicotinamidase-related amidase	205
646814947	309	35.44	1	308	1	313	1.0e-71	263	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
646814948	291	19.66	1	288	2	290	4.0e-06	45.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
646814949	297	18.49	1	291	2	292	1.0e-07	51	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
646814950	188	22.93	4	160	14	168	1.0e-11	63.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646814952	294	54.86	2	289	5	289	2.0e-95	342	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
646814953	382	44.44	3	382	7	390	8.0e-117	413	COG0372	Citrate synthase	390
646814954	864	49.03	2	861	1	861	0.0e+00	1041	COG1048	Aconitase A	861
646814955	392	55.32	5	387	2	375	0.0e+00	474	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
646814956	216	53.46	1	216	4	220	8.0e-85	306	COG0692	Uracil DNA glycosylase	223
646814958	312	48.53	1	306	1	305	2.0e-99	355	COG0181	Porphobilinogen deaminase	307
646814960	607	38.51	10	443	4	446	2.0e-100	359	COG2812	DNA polymerase III, gamma/tau subunits	515
646814961	266	39.7	1	265	6	266	3.0e-69	255	COG0796	Glutamate racemase	269
646814963	268	57.41	3	268	2	268	9.0e-90	323	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
646814964	212	59.91	1	212	10	221	6.0e-68	250	COG2011	ABC-type methionine transport system, permease component	222
646814965	318	45.7	1	318	1	337	7.0e-105	373	COG1135	ABC-type methionine transport system, ATPase component	339
646814966	218	21.43	7	130	1	119	4.0e-09	55	COG3663	G:T/U-mismatch repair DNA glycosylase	169
646814968	1044	28.89	287	668	8	394	2.0e-60	228	COG1061	Superfamily II DNA or RNA helicase	442
646814970	447	63.18	29	447	1	420	0.0e+00	647	COG1158	Transcription termination factor Rho	422
646814971	198	52.82	1	194	3	194	1.0e-66	245	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
646814973	137	62.41	1	133	2	134	8.0e-53	199	COG0105	Nucleoside diphosphate kinase	135
646814975	50	39.22	1	50	1	51	1.0e-06	44.5	COG0333	Ribosomal protein L32	57
646814976	333	50.45	1	331	1	335	1.0e-110	392	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
646814977	332	52.45	1	326	1	320	2.0e-105	376	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
646814983	215	30.09	1	212	1	225	6.0e-33	134	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646814985	293	45.31	1	293	7	314	5.0e-94	337	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
646814987	393	43.4	4	392	11	398	2.0e-110	392	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
646814988	397	12.63	9	364	30	410	2.0e-09	57.1	COG1538	Outer membrane protein TolC	457
646814991	483	44.77	1	468	3	477	0.0e+00	490	COG0469	Pyruvate kinase	477
646814993	211	32.24	1	170	9	179	1.0e-18	87	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
646814995	512	25.97	42	512	6	408	1.0e-44	174	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
646814996	235	25.99	14	227	2	226	4.0e-25	108	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646814999	336	27.41	6	336	20	358	2.0e-55	209	COG1565	SAM-dependent methyltransferase, MidA family	370
646815000	125	41.23	5	118	6	116	5.0e-29	119	COG3564	Uncharacterized conserved protein, DUF779 family	116
646815001	498	40.91	12	490	1	469	0.0e+00	492	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646815002	629	20.4	26	353	30	377	8.0e-24	105	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
646815003	219	30.13	1	218	1	228	1.0e-29	123	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646815005	368	29.82	3	336	13	346	2.0e-43	170	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
646815007	251	36.84	13	235	10	236	2.0e-50	192	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
646815008	98	31.96	1	96	1	96	2.0e-13	67.3	COG1359	Quinol monooxygenase YgiN	100
646815009	304	20.2	1	304	4	263	3.0e-18	85.9	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
646815010	597	28.15	9	595	110	752	3.0e-106	379	COG4993	Glucose dehydrogenase	773
646815012	240	37.77	3	232	2	234	4.0e-51	194	COG1131	ABC-type multidrug transport system, ATPase component	293
646815013	318	29.45	18	299	43	328	1.0e-29	123	COG3391	DNA-binding beta-propeller fold protein YncE	381
646815016	245	27.53	4	241	3	232	4.0e-08	51.8	COG1583	CRISPR/Cas system endoribonuclease Cas6, RAMP superfamily	240
646815018	307	24.85	1	306	2	330	3.0e-11	62.7	COG1857	CRISPR/Cas system-associated protein Cas7,  RAMP superfamily	334
646815020	738	25.6	209	722	169	700	8.0e-52	199	COG1203	CRISPR/Cas system-associated endonuclease/helicase Cas3	733
646815022	164	33.15	1	163	14	187	6.0e-17	80.4	COG1468	CRISPR/Cas system-associated exonuclease Cas4, RecB family	190
646815023	334	32.63	1	331	1	327	1.0e-62	233	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
646815024	104	37.63	11	103	2	89	5.0e-11	59.5	COG1343	CRISPR/Cas system-associated endoribonuclease Cas2	89
646815025	282	32.63	58	144	33	127	1.0e-11	64.3	COG4922	Predicted SnoaL-like aldol condensation-catalyzing enzyme	129
646815026	145	24.07	31	138	19	126	2.0e-11	61.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
646815027	132	29.93	1	132	1	146	7.0e-19	86.2	COG3019	Uncharacterized conserved protein	149
646815028	232	39.35	1	203	3	218	4.0e-56	211	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
646815029	245	25.73	7	245	15	254	3.0e-33	135	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
646815030	317	19.64	5	272	14	277	3.0e-11	62.5	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
646815032	288	18.53	1	283	6	269	4.0e-15	75.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646815034	305	18.91	39	268	14	249	2.0e-20	93.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
646815035	470	40.54	2	469	13	483	2.0e-121	429	COG0260	Leucyl aminopeptidase	485
646815036	281	32.03	1	280	8	286	2.0e-40	159	COG1284	Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains	289
646815037	292	29.8	142	289	4	153	5.0e-19	88.4	COG3449	DNA gyrase inhibitor GyrI	154
646815038	369	34.57	6	368	80	454	2.0e-78	286	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
646815039	66	31.82	1	66	3	68	7.0e-10	55.6	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
646815041	111	27.43	3	110	1	112	3.0e-20	90.3	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
646815042	470	31.95	20	412	19	422	2.0e-55	210	COG0038	H+/Cl- antiporter ClcA	443
646815043	225	20.1	23	212	13	213	8.0e-14	70.6	COG2928	Uncharacterized membrane protein	222
646815044	534	28.38	1	373	4	380	5.0e-43	169	COG0475	Kef-type K+ transport system, membrane component KefB	397
646815045	362	33.16	1	361	6	385	2.0e-73	269	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
646815046	215	34.11	1	212	1	207	9.0e-45	173	COG0288	Carbonic anhydrase	207
646815048	353	46.07	2	352	10	365	2.0e-105	375	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
646815050	204	39.5	1	197	6	199	2.0e-43	168	COG2121	Uncharacterized conserved protein, lysophospholipid acyltransferase (LPLAT) superfamily	214
646815051	439	42.4	5	437	1	436	9.0e-128	450	COG0621	tRNA A37 methylthiotransferase MiaB	437
646815053	391	43.98	171	361	1	180	2.0e-30	126	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
646815054	467	44.92	3	467	1	464	0.0e+00	526	COG0215	Cysteinyl-tRNA synthetase	464
646815056	85	47.76	3	69	9	75	3.0e-16	76.8	COG0238	Ribosomal protein S18	75
646815057	175	30	1	175	2	167	8.0e-28	116	COG0629	Single-stranded DNA-binding protein	167
646815058	120	41.07	5	116	1	112	8.0e-26	109	COG0360	Ribosomal protein S6	112
646815059	327	20.38	1	305	1	313	1.0e-18	87.7	COG1466	DNA polymerase III, delta subunit	334
646815060	618	31.37	154	615	197	703	6.0e-89	321	COG0557	Exoribonuclease R	706
646815061	340	64.29	1	336	1	336	0.0e+00	511	COG0059	Ketol-acid reductoisomerase	338
646815062	388	33.94	169	385	25	243	2.0e-42	166	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
646815064	622	25.78	295	622	56	408	3.0e-27	117	COG0840	Methyl-accepting chemotaxis protein	408
646815065	268	40.15	1	252	2	263	1.0e-37	150	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646815066	265	36.97	56	265	10	220	9.0e-48	183	COG0765	ABC-type amino acid transport system, permease component	222
646815067	257	31.4	10	252	88	344	1.0e-44	173	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
646815068	393	59.49	1	390	4	390	3.0e-126	445	COG3004	Na+/H+ antiporter NhaA	390
646815069	436	32.38	2	436	9	455	2.0e-97	349	COG0773	UDP-N-acetylmuramate-alanine ligase	459
646815071	376	31.91	1	376	5	391	4.0e-66	245	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
646815072	474	35.15	1	471	1	470	2.0e-65	243	COG3400	Uncharacterized protein	471
646815075	485	13.92	23	485	45	450	6.0e-22	99.1	COG1538	Outer membrane protein TolC	457
646815076	376	52.78	14	373	11	363	0.0e+00	478	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
646815077	96	42.71	1	96	1	95	3.0e-17	80.3	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
646815078	113	34.78	1	113	2	116	3.0e-20	90.2	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
646815081	450	64.57	1	446	2	444	0.0e+00	712	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
646815082	330	24.69	8	330	3	239	2.0e-33	136	COG0176	Transaldolase	239
646815083	206	43.41	1	204	5	209	6.0e-50	190	COG0560	Phosphoserine phosphatase	212
646815084	126	33.82	1	126	2	137	1.0e-22	98.8	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
646815086	203	21.78	2	194	1	199	1.0e-20	93.2	COG3417	Outer membrane lipoprotein LpoB, binds and activates PBP1b	200
646815088	444	29.66	7	436	5	438	3.0e-77	282	COG3014	Uncharacterized protein	449
646815089	116	43.9	1	116	4	126	9.0e-25	105	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
646815090	319	40.13	1	314	2	311	1.0e-64	240	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
646815091	274	46.45	1	274	1	282	4.0e-94	337	COG0414	Panthothenate synthetase	285
646815093	446	31.47	8	444	1	437	2.0e-101	363	COG0621	tRNA A37 methylthiotransferase MiaB	437
646815094	324	26.43	3	273	16	293	4.0e-29	122	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
646815096	118	44.44	8	113	11	118	7.0e-19	86.1	COG1516	Flagellin-specific chaperone FliS	132
646815097	533	16.22	184	526	120	483	3.0e-13	70.4	COG1345	Flagellar capping protein FliD	483
646815099	237	26.05	1	231	3	227	3.0e-34	138	COG2063	Flagellar basal body L-ring protein FlgH	230
646815101	176	24.57	1	175	1	158	8.0e-14	70.3	COG1580	Flagellar basal body-associated protein FliL	159
646815104	90	38.75	4	83	5	84	2.0e-10	57.5	COG1987	Flagellar biosynthesis protein FliQ	89
646815106	349	39.89	3	347	9	364	1.0e-70	260	COG1706	Flagellar basal body P-ring protein FlgI	365
646815107	364	34.55	1	330	1	323	7.0e-60	224	COG1868	Flagellar motor switch protein FliM	332
646815108	337	47.98	1	337	1	344	4.0e-115	408	COG0418	Dihydroorotase	344
646815109	112	69.64	1	112	1	112	2.0e-37	147	COG0347	Nitrogen regulatory protein PII	112
646815110	394	35.18	9	390	4	405	2.0e-74	273	COG0004	Ammonia channel protein AmtB	409
646815111	112	72.32	1	112	1	112	1.0e-37	148	COG0347	Nitrogen regulatory protein PII	112
646815112	404	37.29	11	401	4	405	8.0e-82	297	COG0004	Ammonia channel protein AmtB	409
646815115	844	23.21	85	823	67	837	4.0e-81	296	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
646815116	580	35.24	1	578	1	566	2.0e-126	446	COG4232	Thiol:disulfide interchange protein	569
646815118	118	17.09	1	117	1	107	3.0e-09	54.2	COG0607	Rhodanese-related sulfurtransferase	110
646815120	269	26.59	4	266	8	233	7.0e-35	141	COG0688	Phosphatidylserine decarboxylase	239
646815122	362	33.67	72	362	72	366	2.0e-66	246	COG2821	Membrane-bound lytic murein transglycosylase	373
646815124	627	61.63	1	601	4	579	0.0e+00	656	COG0443	Molecular chaperone DnaK (HSP70)	579
646815125	200	42.71	3	200	1	191	4.0e-31	127	COG0576	Molecular chaperone GrpE (heat shock protein)	193
646815128	117	24.3	12	117	9	114	5.0e-07	46.4	COG2361	Uncharacterized conserved protein, contains HEPN domain	117
646815129	105	34.12	21	105	23	97	1.0e-08	51.8	COG1669	Predicted nucleotidyltransferase	97
646815134	382	14.14	6	382	15	393	2.0e-16	80.6	COG2814	Predicted arabinose efflux permease, MFS family	394
646815135	238	28.39	7	236	2	228	1.0e-26	113	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646815136	240	36.07	1	240	2	244	1.0e-63	235	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
646815137	339	18.48	1	321	2	341	6.0e-20	92	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
646815138	256	30.24	7	250	6	242	2.0e-15	76.6	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
646815139	226	52.36	1	226	13	245	1.0e-83	302	COG0020	Undecaprenyl pyrophosphate synthase	245
646815140	420	37.38	1	415	1	388	2.0e-76	279	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
646815141	433	46.41	3	427	2	456	1.0e-126	446	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
646815142	647	20.77	355	561	4	207	5.0e-08	53.4	COG0666	Ankyrin repeat	235
646815144	373	27.03	3	365	69	432	2.0e-73	269	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
646815145	498	30.86	1	266	1	265	7.0e-25	109	COG1344	Flagellin and related hook-associated protein FlgL	360
646815146	495	30.82	1	279	1	272	1.0e-22	101	COG1344	Flagellin and related hook-associated protein FlgL	360
646815147	1219	19.93	83	655	13	581	5.0e-20	94.2	COG2604	Uncharacterized conserved protein	594
646815148	209	50.28	15	191	2	176	3.0e-55	208	COG0279	Phosphoheptose isomerase	176
646815150	333	39.35	1	327	1	333	4.0e-81	295	COG2605	Predicted kinase related to galactokinase and mevalonate kinase	333
646815151	386	28.72	1	386	2	370	7.0e-69	254	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
646815152	312	27.04	4	302	2	309	1.0e-36	147	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646815153	313	26.99	7	313	2	313	3.0e-40	159	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646815154	275	41.35	7	242	10	243	6.0e-63	234	COG3959	Transketolase, N-terminal subunit	243
646815155	304	26.28	2	302	5	310	1.0e-44	173	COG3958	Transketolase, C-terminal subunit	312
646815157	165	34.91	1	165	24	192	2.0e-34	138	COG0529	Adenylylsulfate kinase or related kinase	197
646815158	356	44.25	4	347	30	375	1.0e-99	356	COG2046	ATP sulfurylase (sulfate adenylyltransferase)	397
646815160	247	43.2	1	238	8	256	9.0e-63	233	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
646815162	434	17.97	12	351	18	328	4.0e-21	96.2	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
646815163	486	20.52	23	463	25	460	8.0e-31	128	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
646815165	401	19.75	18	303	42	338	5.0e-07	49.2	COG4641	Spore maturation protein CgeB	373
646815166	365	31.82	5	340	2	347	5.0e-64	238	COG1454	Alcohol dehydrogenase, class IV	377
646815168	428	28.68	144	403	6	254	2.0e-38	153	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
646815169	369	22.09	1	340	15	320	3.0e-26	113	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
646815171	369	18.35	1	301	2	323	2.0e-18	87.2	COG0439	Biotin carboxylase	449
646815173	325	16.27	48	318	100	371	5.0e-10	59.1	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
646815174	340	25.44	5	285	2	276	8.0e-30	124	COG3980	Spore coat polysaccharide biosynthesis protein SpsG, predicted glycosyltransferase	318
646815175	341	54.81	1	340	2	342	2.0e-116	412	COG2089	Sialic acid synthase SpsE, contains C-terminal SAF domain	347
646815176	237	37.89	1	226	1	224	4.0e-52	198	COG1083	CMP-N-acetylneuraminic acid synthetase	228
646815177	376	41.16	1	375	3	372	4.0e-103	368	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
646815180	346	60.84	1	282	3	279	4.0e-83	301	COG0468	RecA/RadA recombinase	279
646815181	424	61.65	1	424	1	423	0.0e+00	613	COG0148	Enolase	423
646815184	385	22.51	1	381	4	389	9.0e-19	88.4	COG0475	Kef-type K+ transport system, membrane component KefB	397
646815185	286	41.01	8	282	46	320	7.0e-74	270	COG0502	Biotin synthase or related enzyme	335
646815186	171	24	1	160	2	171	7.0e-21	93.5	COG0622	Predicted phosphodiesterase	172
646815187	797	48.37	2	573	1	560	0.0e+00	583	COG0550	DNA topoisomerase IA	570
646815188	259	32.39	3	258	2	285	2.0e-49	189	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
646815189	287	40.79	3	278	2	272	1.0e-76	279	COG2107	Predicted periplasmic solute-binding protein	272
646815191	493	34.8	10	485	1	468	1.0e-73	270	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
646815192	508	48.07	3	491	4	492	0.0e+00	471	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
646815193	643	37.87	5	635	1	606	5.0e-113	402	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
646815194	99	49.49	1	99	2	100	6.0e-22	95.9	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
646815195	190	36.36	1	165	2	165	4.0e-18	84.9	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
646815196	207	35	30	207	1	169	7.0e-31	127	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
646815197	335	48.65	6	333	11	332	1.0e-80	293	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
646815198	824	21.51	4	778	1	692	2.0e-95	344	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
646815201	408	53	9	408	1	398	0.0e+00	543	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
646815202	273	33.9	31	205	1	176	2.0e-33	135	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
646815203	169	62.73	10	169	15	175	1.0e-70	259	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
646815204	129	43.55	3	125	1	120	3.0e-26	110	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
646815205	577	22.82	160	566	84	486	3.0e-28	120	COG0464	AAA+-type ATPase, SpoVK/Ycf46/Vps4 family	494
646815210	556	20.4	17	353	18	363	3.0e-08	53.8	COG1479	Uncharacterized conserved protein, contains ParB-like and HNH nuclease domains	409
646815211	286	44.09	14	286	4	271	3.0e-52	198	COG0338	Site-specific DNA-adenine methylase	274
646815212	263	30.04	4	260	7	264	4.0e-34	138	COG0863	DNA modification methylase	302
646815214	281	43.46	1	281	1	277	3.0e-83	301	COG0648	Endonuclease IV	280
646815215	563	33.39	7	558	6	522	2.0e-106	379	COG1620	L-lactate permease	522
646815217	803	30.7	441	741	76	404	8.0e-40	159	COG0840	Methyl-accepting chemotaxis protein	408
646815218	187	16.31	21	161	15	147	9.0e-14	70	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
646815219	465	63.15	1	464	1	462	0.0e+00	745	COG0114	Fumarate hydratase class II	462
646815221	327	22.48	25	318	7	283	2.0e-23	103	COG2301	Citrate lyase beta subunit	283
646815222	354	31.29	10	154	13	157	7.0e-17	81.7	COG2030	Acyl dehydratase	159
646815223	839	26.82	6	537	1	524	4.0e-95	343	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
646815224	377	24.75	53	341	11	274	5.0e-23	102	COG2301	Citrate lyase beta subunit	283
646815225	241	29.91	6	233	1	233	7.0e-37	147	COG1414	DNA-binding transcriptional regulator, IclR family	246
646815228	357	42.11	1	208	6	204	1.0e-55	210	COG1636	Predicted ATPase, Adenine nucleotide alpha hydrolases (AANH) superfamily	204
646815229	347	35.71	1	345	2	375	7.0e-76	277	COG0763	Lipid A disaccharide synthetase	381
646815230	147	51.68	1	147	3	146	8.0e-43	166	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
646815231	262	55.08	1	254	3	258	5.0e-91	327	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
646815232	407	60.55	8	406	2	395	0.0e+00	564	COG1219	ATP-dependent protease Clp, ATPase subunit	408
646815233	343	59.35	6	338	1	336	4.0e-112	398	COG1077	Actin-like ATPase involved in cell morphogenesis	342
646815234	244	21.29	1	234	20	267	6.0e-13	68.1	COG1792	Cell shape-determining protein MreC	284
646815235	668	29.8	433	668	2	245	3.0e-46	180	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
646815237	205	40.2	1	191	1	199	3.0e-57	215	COG0307	Riboflavin synthase alpha chain	204
646815238	630	57.58	2	621	4	617	0.0e+00	873	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
646815240	230	23.5	1	193	1	210	9.0e-09	53.9	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
646815241	840	26.97	525	829	80	408	6.0e-32	133	COG0840	Methyl-accepting chemotaxis protein	408
646815246	344	39.45	1	331	1	364	1.0e-86	313	COG1858	Cytochrome c peroxidase	364
646815247	158	32.26	33	155	4	126	2.0e-10	58.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
646815248	410	16.96	19	402	45	443	8.0e-36	144	COG1538	Outer membrane protein TolC	457
646815249	357	26.54	1	353	14	367	6.0e-37	148	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646815250	1042	45	1	1028	1	1009	0.0e+00	955	COG0841	Multidrug efflux pump subunit AcrB	1009
646815252	469	26.01	14	384	8	354	3.0e-49	189	COG0348	Polyferredoxin	386
646815253	538	57.67	2	538	1	530	0.0e+00	792	COG0504	CTP synthase (UTP-ammonia lyase)	533
646815254	520	35.06	22	490	7	478	3.0e-88	319	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
646815257	183	32.09	1	171	2	188	1.0e-23	102	COG0693	Putative intracellular protease/amidase	188
646815259	705	22.92	41	416	49	400	1.0e-36	148	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
646815260	405	21.41	16	360	14	360	3.0e-27	116	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646815261	242	35.27	6	242	1	234	4.0e-49	188	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
646815262	251	25.45	4	251	12	289	2.0e-29	122	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
646815263	1180	47.84	5	1107	2	1071	0.0e+00	1200	COG0587	DNA polymerase III, alpha subunit	1139
646815264	262	45.59	1	261	1	252	2.0e-77	282	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
646815268	156	54.49	1	156	2	156	3.0e-55	207	COG0315	Molybdenum cofactor biosynthesis enzyme	157
646815269	70	40.3	1	67	1	67	9.0e-06	41.8	COG0828	Ribosomal protein S21	67
646815270	488	48.67	1	488	3	482	0.0e+00	565	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
646815271	227	42.79	1	227	2	216	1.0e-71	263	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
646815280	231	37.73	20	231	15	233	2.0e-26	113	COG0670	Integral membrane protein, interacts with FtsH	233
646815283	128	39.47	1	75	1	76	6.0e-15	73.3	COG1314	Preprotein translocase subunit SecG	86
646815284	185	51.89	1	185	3	187	3.0e-57	215	COG0233	Ribosome recycling factor	187
646815285	202	33.33	1	201	5	201	3.0e-35	141	COG0461	Orotate phosphoribosyltransferase	201
646815286	161	18.05	30	157	18	149	1.0e-06	46.3	COG1714	Uncharacterized membrane protein YckC, RDD family	172
646815287	362	17.34	1	356	13	379	1.0e-06	47.9	COG2814	Predicted arabinose efflux permease, MFS family	394
646815288	846	31.91	609	840	5	239	8.0e-56	212	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
646815289	245	24.12	1	242	1	250	2.0e-29	122	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
646815290	138	31.3	8	135	4	129	2.0e-24	105	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
646815293	390	18.21	1	387	6	389	1.0e-15	78.3	COG2814	Predicted arabinose efflux permease, MFS family	394
646815294	464	38.63	2	464	13	472	2.0e-104	373	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646815295	551	37.73	1	533	2	535	0.0e+00	506	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
646815296	217	28.7	1	213	4	217	4.0e-40	157	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
646815299	709	40.78	534	708	2	180	6.0e-45	176	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646815300	114	31.43	1	102	1	105	5.0e-14	69.6	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
646815303	121	23.64	10	119	10	111	5.0e-07	46.4	COG2361	Uncharacterized conserved protein, contains HEPN domain	117
646815304	96	32.99	1	95	1	96	2.0e-11	60.6	COG1669	Predicted nucleotidyltransferase	97
646815308	409	33.41	1	407	4	404	2.0e-86	312	COG2081	Predicted flavoprotein YhiN	408
646815310	370	24.46	14	364	22	382	9.0e-33	134	COG3864	Predicted metal-dependent peptidase	396
646815311	388	28.69	12	372	13	366	5.0e-35	142	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646815312	1042	54.67	1	1024	2	1009	0.0e+00	1005	COG0841	Multidrug efflux pump subunit AcrB	1009
646815313	474	30.18	16	469	1	442	2.0e-68	253	COG1538	Outer membrane protein TolC	457
646815315	422	54.61	1	421	6	423	0.0e+00	535	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
646815317	309	54	5	301	3	300	1.0e-108	386	COG0031	Cysteine synthase	300
646815318	74	22.81	10	66	2	58	6.0e-07	45.7	COG3205	Uncharacterized membrane protein	72
646815319	233	41.53	1	232	11	242	9.0e-58	216	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
646815320	303	33.22	8	303	17	261	4.0e-53	201	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
646815321	486	54.98	19	459	1	426	0.0e+00	582	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
646815322	529	31.11	10	529	9	498	1.0e-95	344	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
646815323	434	29.55	18	433	11	403	4.0e-69	255	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
646815325	402	18.26	58	388	79	376	2.0e-17	84.3	COG4222	Uncharacterized conserved protein	391
646815327	371	32.13	140	370	37	282	4.0e-36	145	COG1408	Predicted phosphohydrolase, MPP superfamily	284
646815329	743	32.55	425	740	69	408	3.0e-33	137	COG0840	Methyl-accepting chemotaxis protein	408
646815330	1121	49.37	284	1066	1	784	0.0e+00	861	COG4196	Uncharacterized conserved protein, DUF2126 family	808
646815331	831	36.32	13	480	12	478	0.0e+00	482	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
646815332	297	24.67	1	296	11	309	3.0e-35	142	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
646815334	454	39.78	1	453	15	477	4.0e-122	431	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
646815336	137	37.32	1	137	5	146	5.0e-20	90.4	COG0071	Molecular chaperone IbpA, HSP20 family	146
646815338	322	20.72	2	321	4	320	1.0e-09	57.6	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
646815340	604	60.8	1	601	2	603	0.0e+00	921	COG1217	Predicted membrane GTPase involved in stress response	603
646815341	79	39.73	8	79	4	76	2.0e-15	74.1	COG0425	TusA-related sulfurtransferase	78
646815342	305	47.06	1	305	4	309	2.0e-108	386	COG2066	Glutaminase	309
646815343	609	18.46	290	609	10	327	4.0e-17	83.3	COG0642	Signal transduction histidine kinase	336
646815344	224	21.78	11	221	2	224	7.0e-20	90.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646815346	561	23.02	1	561	3	554	1.0e-64	241	COG2831	Hemolysin activation/secretion protein	554
646815347	609	19.88	277	609	2	327	2.0e-17	84.8	COG0642	Signal transduction histidine kinase	336
646815348	224	24.66	11	220	2	223	1.0e-17	83.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646815351	360	17.02	21	352	31	402	8.0e-12	64.9	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
646815352	208	45.7	2	208	1	221	1.0e-58	219	COG1136	ABC-type lipoprotein export system, ATPase component	226
646815357	243	26.91	16	240	40	284	4.0e-21	95.1	COG1408	Predicted phosphohydrolase, MPP superfamily	284
646815358	222	44.54	1	222	1	228	1.0e-56	212	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646815359	456	29.56	137	451	19	327	1.0e-39	157	COG0642	Signal transduction histidine kinase	336
646815360	498	36.11	5	491	11	534	5.0e-109	388	COG0659	Sulfate permease or related transporter, MFS superfamily	554
646815361	277	26.39	159	277	8	151	5.0e-11	61.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
646815362	532	36.4	1	527	7	541	1.0e-113	403	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
646815363	231	29.59	21	214	42	231	8.0e-27	113	COG3907	Membrane-associated enzyme, PAP2 (acid phosphatase) superfamily	249
646815364	119	35.59	2	119	4	121	1.0e-21	95.2	COG0818	Diacylglycerol kinase	123
646815367	258	31.28	1	193	2	192	2.0e-24	106	COG3658	Cytochrome b	192
646815370	221	32.6	4	220	2	226	1.0e-51	195	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646815371	397	27.54	127	384	40	314	6.0e-18	85.6	COG0642	Signal transduction histidine kinase	336
646815372	201	33	1	200	3	201	1.0e-27	116	COG2860	Uncharacterized membrane protein YeiH	209
646815373	308	43.43	132	306	7	180	1.0e-45	177	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646815374	205	21.29	10	205	10	203	2.0e-12	66.1	COG1776	Chemotaxis protein CheY-P-specific phosphatase CheC	203
646815376	191	34.55	2	191	1	186	9.0e-49	186	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
646815378	157	47.68	6	155	1	150	2.0e-45	175	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
648022649	409	20.39	93	394	2	297	3.0e-08	53.4	COG0582	Integrase	309
