gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
2918239082	399	99.75	1	397	1	403	3.0e-130	429.3	COG0162	Tyrosyl-tRNA synthetase	401
2918239083	471	93.99	107	449	2	298	3.8e-63	208.8	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2918239084	363	98.4	1	363	5	372	0.0e+00	458.3	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
2918239085	116	97.27	7	116	4	110	1.3e-43	141.9	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2918239086	344	99.71	1	344	2	349	3.2e-130	428.7	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
2918239087	141	96.64	1	141	6	149	6.9e-63	205.8	COG1981	Uncharacterized membrane protein	149
2918239088	315	98.26	1	313	3	341	4.3e-76	250.8	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2918239089	260	96.98	1	255	6	262	5.0e-79	259.5	COG0300	Short-chain dehydrogenase	265
2918239090	112	76.6	1	112	2	109	8.5e-37	120.6	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2918239091	215	100	10	215	1	207	2.6e-75	246.8	COG2941	Demethoxyubiquinone hydroxylase, CLK1/Coq7/Cat5 family	204
2918239094	140	98.54	1	138	2	136	7.8e-47	153	COG1765	Uncharacterized OsmC-related protein	137
2918239095	214	90.37	10	214	22	218	1.8e-43	142.9	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918239096	235	61.75	3	192	15	169	9.9e-25	81.3	COG0095	Lipoate-protein ligase A	248
2918239097	278	99.61	7	265	1	253	1.3e-96	317	COG0134	Indole-3-glycerol phosphate synthase	254
2918239098	349	98.82	1	341	2	337	2.5e-129	425.3	COG0547	Anthranilate phosphoribosyltransferase	338
2918239099	197	98.43	1	193	3	190	3.7e-81	265.5	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
2918239100	622	98.67	2	350	5	374	8.3e-68	220.5	COG3240	Phospholipase/lecithinase/hemolysin	370
2918239100	622	99.16	378	622	2	238	2.6e-23	77	COG5571	Uncharacterized protein YhjY, contains autotransporter beta-barrel domain	239
2918239101	493	98.72	18	492	5	465	0.0e+00	567.3	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2918239102	272	95.5	12	229	5	216	1.8e-57	188.9	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918239103	224	98.18	1	222	2	217	6.3e-93	304.3	COG0036	Pentose-5-phosphate-3-epimerase	220
2918239104	275	95.13	6	272	11	264	2.7e-90	296.5	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918239105	415	11.81	16	87	10	43	4.7e-90	6.2	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918239105	415	91.32	129	413	16	278	4.7e-90	290.4	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918239106	343	96.56	1	341	13	377	1.8e-68	225.6	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918239107	374	97.73	10	368	4	348	0.0e+00	435.9	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918239108	209	99.53	2	209	1	210	7.7e-65	212.8	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918239109	795	86.93	375	794	50	375	2.4e-66	219	COG4585	Signal transduction histidine kinase	365
2918239109	795	92.58	1	272	13	274	2.3e-20	67	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918239111	260	100	76	255	1	174	9.9e-28	91.3	COG1076	DnaJ-domain-containing proteins 1	174
2918239112	223	62.7	1	223	2	238	1.1e-62	206.5	COG1208	NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins	358
2918239113	339	90.03	5	338	27	342	4.8e-120	394.8	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
2918239114	936	95.35	64	933	35	793	0.0e+00	709	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
2918239115	439	46.77	282	431	167	318	4.9e-97	147.4	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918239115	439	80	8	285	11	270	4.9e-97	175.6	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918239116	329	98.19	2	329	5	329	1.6e-129	426.4	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
2918239117	267	98.08	6	265	3	257	2.2e-91	299.9	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
2918239118	126	98.41	1	126	3	126	9.7e-55	178.3	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
2918239119	287	89.24	40	264	13	153	3.6e-15	50.9	COG0639	Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family	155
2918239120	109	92.98	1	104	3	108	6.4e-27	88.2	COG0607	Rhodanese-related sulfurtransferase	110
2918239121	640	99.85	1	640	1	649	0.0e+00	984.5	COG2766	Predicted Ser/Thr protein kinase	649
2918239122	423	99.06	1	423	1	420	0.0e+00	599.7	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
2918239123	522	97.18	5	508	7	488	0.0e+00	765.6	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
2918239124	381	23.61	246	363	301	398	4.9e-80	16.7	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
2918239124	381	59.04	1	252	23	267	4.9e-80	246.2	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
2918239125	169	95.65	3	157	3	156	2.5e-34	112.4	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
2918239126	118	94.21	1	117	3	116	1.0e-34	113.7	COG1539	Dihydroneopterin aldolase	121
2918239127	189	97.07	1	189	5	203	8.4e-60	196.4	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
2918239128	341	98.55	1	341	1	339	0.0e+00	442.9	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
2918239129	71	98.51	1	67	1	66	5.0e-32	104.2	COG0828	Ribosomal protein S21	67
2918239130	667	96.81	11	661	2	578	0.0e+00	604.9	COG0358	DNA primase (bacterial type)	568
2918239131	616	10.85	33	236	63	99	0.0e+00	6.5	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918239131	616	98.53	260	615	6	341	0.0e+00	443.9	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918239132	1247	58.26	408	552	100	240	8.4e-58	44.9	COG2202	PAS domain	232
2918239132	1247	58.68	659	800	100	241	8.4e-58	60.2	COG2202	PAS domain	232
2918239132	1247	59.5	145	429	99	242	8.4e-58	57.6	COG2202	PAS domain	232
2918239132	1247	64.1	769	1240	218	642	8.5e-112	368.2	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918239132	1247	76.45	496	678	55	239	8.4e-58	55.1	COG2202	PAS domain	232
2918239135	227	10.98	12	52	5	33	4.6e-11	1.8	COG3306	Glycosyltransferase involved in LPS biosynthesis, GR25 family	255
2918239135	227	12.88	44	103	68	101	4.6e-11	29.9	COG3306	Glycosyltransferase involved in LPS biosynthesis, GR25 family	255
2918239135	227	15.53	121	220	158	198	4.6e-11	2.4	COG3306	Glycosyltransferase involved in LPS biosynthesis, GR25 family	255
2918239137	153	90.51	5	150	6	148	1.0e-29	97.9	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918239138	560	32.38	39	283	4	150	5.1e-31	45	COG1231	Monoamine oxidase	450
2918239138	560	47.58	296	536	233	448	5.1e-31	55.8	COG1231	Monoamine oxidase	450
2918239139	265	97.84	1	265	3	274	2.0e-70	231.3	COG0388	Predicted amidohydrolase	274
2918239140	779	5.52	440	510	558	609	1.6e-82	2.9	COG1025	Secreted/periplasmic Zn-dependent peptidases, insulinase-like	937
2918239140	779	6.48	593	716	762	822	1.6e-82	41.3	COG1025	Secreted/periplasmic Zn-dependent peptidases, insulinase-like	937
2918239140	779	36.09	3	368	24	363	1.6e-82	224.4	COG1025	Secreted/periplasmic Zn-dependent peptidases, insulinase-like	937
2918239141	303	97.44	1	303	4	269	3.2e-43	142.3	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2918239142	251	98.35	3	242	5	242	3.7e-89	292.6	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
2918239144	386	93.58	12	353	21	355	1.8e-69	228.8	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2918239145	609	76.49	67	609	154	667	1.6e-86	285.5	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
2918239146	52	92.86	1	52	4	55	5.1e-28	91.2	COG0401	Uncharacterized membrane protein YqaE, homolog of Blt101, UPF0057 family	56
2918239147	425	96.05	23	418	14	402	7.3e-122	401	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2918239148	307	97.67	1	298	1	294	2.8e-60	198.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918239150	592	96.99	17	462	7	393	8.0e-99	325.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918239151	427	89.62	185	415	19	182	5.7e-42	137.8	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918239153	601	97.74	18	462	6	395	3.4e-103	339.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918239155	226	98.21	1	226	1	219	2.1e-68	224.7	COG0132	Dethiobiotin synthetase	223
2918239156	274	69.46	12	216	10	175	1.1e-24	81.1	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918239157	243	90.85	4	240	25	292	1.0e-18	61.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918239158	390	98.46	1	382	5	388	0.0e+00	455.7	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
2918239159	352	95.27	1	333	7	328	0.0e+00	449.4	COG0502	Biotin synthase or related enzyme	335
2918239160	210	87.5	1	205	28	223	2.5e-60	198.2	COG1040	Predicted amidophosphoribosyltransferases	225
2918239161	254	88.41	188	253	7	67	2.5e-14	6.9	COG3585	Molybdopterin-binding protein	69
2918239161	254	89.31	2	121	15	131	2.5e-37	121.7	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
2918239161	254	91.3	113	180	3	65	2.5e-14	38.9	COG3585	Molybdopterin-binding protein	69
2918239162	324	97.61	1	324	7	333	4.6e-81	266.5	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2918239163	295	97.97	1	295	6	294	3.7e-111	365.5	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
2918239164	172	97.16	1	171	3	173	3.0e-56	184.1	COG2716	Glycine cleavage system regulatory protein	176
2918239165	725	99.83	4	723	2	576	0.0e+00	789.7	COG2225	Malate synthase	545
2918239166	147	24.84	23	147	5	120	1.6e-26	87.5	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918239167	645	98.69	18	645	7	608	0.0e+00	452.5	COG2905	Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains	610
2918239168	236	13.06	25	234	419	607	2.3e-23	76	COG2176	DNA polymerase III, alpha subunit (gram-positive type)	1444
2918239169	172	86.56	2	171	17	177	2.2e-36	119.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918239170	318	97.52	1	318	8	322	5.7e-87	286	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918239171	810	97.86	34	810	18	795	1.1e-113	375.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918239172	370	87.13	1	370	1	386	4.9e-67	221.1	COG3182	Uncharacterized iron-regulated membrane protein	442
2918239175	480	20	361	444	96	136	1.5e-07	7.6	COG3642	tRNA A-37 threonylcarbamoyl transferase component Bud32	204
2918239175	480	42.93	65	185	48	135	1.5e-07	14.8	COG3642	tRNA A-37 threonylcarbamoyl transferase component Bud32	204
2918239176	250	44.65	20	219	63	208	1.2e-04	15.5	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2918239177	244	51.22	49	236	36	140	1.4e-07	24.8	COG3642	tRNA A-37 threonylcarbamoyl transferase component Bud32	204
2918239178	268	45.85	69	237	49	142	3.6e-04	13.3	COG3642	tRNA A-37 threonylcarbamoyl transferase component Bud32	204
2918239179	374	90.95	1	366	14	385	1.2e-25	85.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918239180	352	92.06	1	349	3	315	9.2e-83	272.7	COG0859	ADP-heptose:LPS heptosyltransferase	334
2918239181	349	98.53	1	340	2	336	1.3e-100	331.3	COG0859	ADP-heptose:LPS heptosyltransferase	334
2918239182	977	97.3	2	976	16	952	0.0e+00	1158	COG1391	Glutamine synthetase adenylyltransferase	963
2918239183	881	99.1	1	881	7	885	0.0e+00	1466.7	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
2918239184	547	26.73	2	121	5	120	0.0e+00	101.2	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2918239184	547	99.31	118	547	3	433	0.0e+00	462.4	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2918239186	897	64.1	380	896	218	642	2.0e-111	367.2	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918239187	221	91.95	47	219	8	167	1.1e-67	221.6	COG0225	Peptide methionine sulfoxide reductase MsrA	174
2918239188	207	94.88	4	207	1	204	1.3e-34	114.3	COG0625	Glutathione S-transferase	211
2918239189	442	97.74	1	442	1	433	0.0e+00	510.9	COG4452	Inner membrane protein involved in colicin E2 resistance	443
2918239190	477	84.26	90	476	57	388	4.3e-55	181.7	COG0642	Signal transduction histidine kinase	336
2918239191	226	98.71	2	225	2	230	2.3e-75	247.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918239192	168	96.91	1	165	3	159	2.5e-57	187.3	COG4067	Uncharacterized conserved protein	162
2918239193	295	98.47	20	283	3	259	1.6e-33	110.4	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918239194	454	93.9	7	452	8	469	1.2e-66	219.5	COG0531	Amino acid transporter	466
2918239201	399	99.15	4	392	4	353	8.1e-92	301.8	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918239202	103	92	2	100	7	98	5.7e-31	101	COG3657	Putative component of the toxin-antitoxin plasmid stabilization module	100
2918239203	153	91	15	112	7	97	1.3e-24	80.2	COG3636	DNA-binding prophage protein	100
2918239204	285	99.3	1	285	2	286	1.7e-116	383.2	COG0788	Formyltetrahydrofolate hydrolase	287
2918239205	210	97.35	14	206	5	188	1.4e-49	163	COG4583	Sarcosine oxidase gamma subunit	189
2918239206	1004	98.96	610	1004	3	383	1.7e-118	389.7	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
2918239206	1004	99.77	21	484	1	429	2.3e-76	252	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918239207	111	95.96	1	103	1	95	5.9e-43	139.5	COG4311	Sarcosine oxidase delta subunit	97
2918239208	416	98.71	29	406	3	385	4.4e-86	283.9	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918239209	417	99.04	2	417	4	414	0.0e+00	652.3	COG0112	Glycine/serine hydroxymethyltransferase	413
2918239210	346	99.42	5	345	2	342	1.8e-129	425.9	COG2008	Threonine aldolase	342
2918239211	645	86.12	175	645	60	425	1.1e-111	368.1	COG0840	Methyl-accepting chemotaxis protein	408
2918239212	100	84.76	5	100	6	94	1.4e-13	45.2	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
2918239213	76	31.06	9	75	34	83	1.7e-03	12.3	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2918239214	541	91.53	106	541	36	424	2.3e-104	343.7	COG0840	Methyl-accepting chemotaxis protein	408
2918239215	366	99.63	14	306	1	267	3.4e-85	279.9	COG1018	Ferredoxin-NADP reductase	266
2918239216	430	97.61	27	422	3	369	4.9e-101	332.9	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918239218	256	91.57	2	256	22	260	1.3e-40	133.5	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2918239219	410	98.74	93	401	4	317	2.4e-65	215.5	COG2025	Electron transfer flavoprotein, alpha subunit	313
2918239220	650	99	235	631	2	398	2.6e-101	333.7	COG0247	Fe-S oxidoreductase	388
2918239221	686	98.9	1	368	2	360	2.1e-107	353.7	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918239223	325	99.69	1	325	2	318	1.4e-101	334.2	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
2918239224	133	92.97	1	133	8	126	2.4e-12	41.3	COG3755	Uncharacterized conserved protein YecT, DUF1311 family	127
2918239225	315	95.08	1	314	9	317	5.2e-111	365	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918239226	314	95.74	2	302	13	304	5.8e-79	259.5	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
2918239227	294	99.66	1	294	1	297	2.0e-119	392.7	COG3246	Uncharacterized conserved protein, DUF849 family	298
2918239228	321	86.02	5	317	2	284	2.0e-74	245	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918239229	156	94.24	1	138	6	136	1.5e-27	90.6	COG0824	Acyl-CoA thioesterase FadM	137
2918239232	555	93.57	1	554	26	593	0.0e+00	576.2	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
2918239233	928	78.95	21	408	14	358	2.2e-53	148.3	COG0612	Predicted Zn-dependent peptidase	438
2918239233	928	95.42	509	926	16	432	2.2e-53	29.5	COG0612	Predicted Zn-dependent peptidase	438
2918239235	322	96.28	2	322	11	321	5.1e-85	279.5	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918239236	31	16.13	1	31	151	180	7.4e-05	17	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918239237	139	69.35	2	134	19	147	5.5e-27	88.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918239238	368	96.62	9	332	4	317	3.1e-126	414.9	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918239239	458	25.82	4	84	53	123	1.6e-122	15.9	COG1760	L-serine deaminase	262
2918239239	458	99.64	171	454	1	274	1.6e-122	385.3	COG1760	L-serine deaminase	262
2918239240	315	96.72	1	302	10	304	1.0e-94	311.3	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
2918239241	281	93.13	1	280	8	278	8.3e-114	374.1	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
2918239242	392	98.97	1	390	3	386	0.0e+00	479.9	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
2918239243	256	98.83	2	256	2	255	2.3e-118	388.4	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
2918239244	245	98.76	1	243	2	239	1.2e-92	303.8	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
2918239245	86	92.68	8	86	4	79	1.2e-15	51.7	COG5460	Uncharacterized conserved protein, DUF2164 family	82
2918239246	212	99.02	1	210	1	202	6.6e-77	252.3	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
2918239247	197	98.97	1	197	3	195	2.5e-85	279.4	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
2918239248	552	56.4	28	297	17	232	5.2e-21	39.6	COG0477	MFS family permease	338
2918239248	552	56.66	269	551	8	224	5.2e-21	33.1	COG0477	MFS family permease	338
2918239249	748	99.41	2	740	4	676	2.0e-116	384.6	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2918239250	355	97.18	1	347	9	352	1.3e-127	420.6	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
2918239251	90	98.89	1	90	1	89	3.4e-42	136.8	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
2918239253	100	92	1	96	4	95	1.2e-40	131.8	COG3636	DNA-binding prophage protein	100
2918239254	60	58	1	60	40	97	2.3e-26	86.4	COG3657	Putative component of the toxin-antitoxin plasmid stabilization module	100
2918239255	326	90	29	298	27	269	3.4e-117	385	COG2326	Polyphosphate kinase 2, PPK2 family	270
2918239258	464	97.62	1	460	7	457	0.0e+00	538.7	COG1113	L-asparagine transporter and related permeases	462
2918239259	257	98.83	2	257	3	255	0.0e+00	447.9	COG4598	ABC-type histidine transport system, ATPase component	256
2918239260	251	95.41	1	251	5	274	2.1e-65	215.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918239261	230	98.7	3	229	3	229	1.7e-91	300	COG4215	ABC-type arginine transport system, permease component	230
2918239262	229	97.81	1	226	1	223	8.5e-92	301	COG4160	ABC-type arginine/histidine transport system, permease component	228
2918239270	204	88.94	1	201	1	201	3.8e-40	131.7	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2918239272	967	76.67	99	850	96	785	4.0e-70	230.7	COG5281	Phage-related minor tail protein	833
2918239278	599	68.51	56	579	105	500	2.7e-51	168.9	COG5519	Uncharcterized protein, DUF927 family	562
2918239279	296	73.5	22	294	38	306	2.3e-61	202	COG4643	Uncharacterized domain associated with phage/plasmid primase	366
2918239291	72	65.71	22	72	18	63	2.5e-10	33.6	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2918239292	482	80.3	96	451	45	313	1.7e-20	67.9	COG0582	Integrase	309
2918239293	150	46.38	90	139	7	38	3.8e-03	10.4	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2918239295	759	97.78	3	759	17	720	0.0e+00	598.2	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
2918239296	235	97.84	3	234	3	229	7.7e-70	229.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918239297	462	88.07	94	462	43	389	1.1e-50	167.2	COG0642	Signal transduction histidine kinase	336
2918239299	368	98.84	1	365	4	345	0.0e+00	481	COG2957	Agmatine/peptidylarginine deiminase	346
2918239300	966	94.63	7	352	5	321	9.8e-77	251.6	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2918239300	966	96.19	532	965	16	444	1.4e-120	397	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2918239301	179	97.18	1	176	5	176	5.8e-69	225.5	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
2918239302	614	99.17	17	601	5	603	0.0e+00	642.7	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2918239303	470	97.86	8	459	5	461	0.0e+00	569	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918239305	275	97.1	1	272	7	274	4.7e-85	279.5	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
2918239306	188	85.47	33	185	12	158	4.6e-16	53.5	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918239307	220	97.84	6	220	1	226	4.2e-29	96.5	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918239308	303	94.31	12	300	5	286	4.5e-49	161.5	COG4823	Abortive infection bacteriophage resistance protein	299
2918239309	146	53.15	1	146	129	280	4.9e-27	87	COG1652	Nucleoid-associated protein YgaU, contains BON and LysM domains	269
2918239310	275	92.88	15	275	13	260	9.4e-70	229.2	COG1526	Formate dehydrogenase assembly factor FdhD	266
2918239311	779	97.28	17	773	22	809	0.0e+00	434.9	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918239315	144	97.12	7	143	2	136	1.4e-21	71.3	COG0824	Acyl-CoA thioesterase FadM	137
2918239317	90	93.94	1	90	2	94	1.3e-16	55.5	COG3668	Plasmid stabilization system protein ParE	98
2918239318	513	96.98	1	513	15	527	0.0e+00	728.5	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
2918239319	300	99.3	4	286	3	287	7.0e-93	305.4	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
2918239320	251	81.47	1	238	27	215	4.5e-15	50.7	COG0671	Membrane-associated phospholipid phosphatase	232
2918239321	133	97	1	104	3	99	1.1e-34	113.1	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
2918239322	160	87.65	2	146	20	161	3.6e-51	167.2	COG4067	Uncharacterized conserved protein	162
2918239323	301	98.73	1	291	1	311	3.3e-83	272.8	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2918239324	437	80.96	33	434	71	389	1.0e-57	190.8	COG0642	Signal transduction histidine kinase	336
2918239325	246	98.71	11	242	2	230	1.8e-79	260.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918239326	774	98.85	1	772	8	780	0.0e+00	1086	COG2183	Transcriptional accessory protein Tex/SPT6	780
2918239327	128	85.82	2	128	17	137	7.8e-39	126.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918239328	525	98.65	1	517	4	514	0.0e+00	655.4	COG2918	Gamma-glutamylcysteine synthetase	518
2918239329	208	93.78	1	204	6	201	4.2e-19	64.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918239330	71	97.1	4	71	2	68	5.3e-31	101.1	COG3585	Molybdopterin-binding protein	69
2918239331	270	95.62	15	251	5	244	5.1e-86	282.4	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918239332	265	97.29	1	258	7	257	2.9e-91	299.8	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918239333	382	98.83	8	356	1	339	4.8e-89	293.1	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918239334	321	96.42	2	321	6	328	2.5e-76	251.4	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918239335	197	95.65	1	183	2	177	1.2e-41	136.7	COG0431	NAD(P)H-dependent FMN reductase	184
2918239336	212	98.96	1	192	2	191	5.7e-71	232.3	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
2918239338	323	95.21	3	323	12	329	0.0e+00	481.9	COG4521	ABC-type taurine transport system, periplasmic component	334
2918239339	264	99.23	1	259	1	257	1.2e-118	389.6	COG4525	ABC-type taurine transport system, ATPase component	259
2918239340	279	95.74	19	279	10	256	3.6e-82	269.9	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918239341	277	97.91	1	277	3	283	7.7e-97	318.5	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2918239342	297	96.25	1	268	9	265	6.0e-91	298.6	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918239343	306	95.49	6	306	8	282	3.4e-110	362.2	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918239344	380	98.87	18	380	3	351	4.8e-130	428.2	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918239345	364	95.77	2	364	16	377	1.6e-114	377.1	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918239346	365	98.41	1	365	6	377	2.8e-113	373.2	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918239347	453	98.21	7	453	6	444	0.0e+00	541.1	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918239348	452	98.65	3	451	5	444	1.1e-130	430.6	COG0174	Glutamine synthetase	443
2918239350	458	98.65	9	457	6	445	0.0e+00	440	COG0174	Glutamine synthetase	443
2918239351	432	94.77	286	432	2	146	1.1e-53	174.9	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
2918239351	432	98.87	19	282	3	264	2.8e-73	240.4	COG0548	Acetylglutamate kinase	265
2918239352	380	95.69	2	379	17	416	1.2e-76	252.6	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918239353	466	99.33	1	461	1	445	3.9e-99	326.9	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
2918239354	156	98.1	1	154	3	157	9.0e-41	133.8	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918239355	108	63.33	25	97	30	86	1.2e-03	13.4	COG2921	Putative lipoic acid-binding regulatory protein	90
2918239356	555	96.65	84	555	16	506	0.0e+00	498.8	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2918239358	957	31.39	184	385	194	349	0.0e+00	26.2	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2918239358	957	94.37	455	929	28	496	0.0e+00	698.1	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2918239359	127	96.18	1	127	3	128	3.1e-50	163.7	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
2918239360	360	97.14	1	358	6	379	5.0e-119	391.7	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
2918239361	540	97.43	2	539	10	539	0.0e+00	460.6	COG1178	ABC-type Fe3+ transport system, permease component	540
2918239362	333	99.67	40	333	2	301	7.6e-67	220.1	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918239363	407	99.24	3	399	3	392	5.9e-112	369.3	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918239365	399	98.73	2	391	4	391	1.2e-90	299.1	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918239366	444	98.21	1	433	7	389	1.2e-101	334.8	COG0006	Xaa-Pro aminopeptidase	384
2918239367	184	99.46	1	184	2	186	1.0e-48	159.9	COG3079	Uncharacterized conserved protein YgfB, UPF0149 family	186
2918239369	105	90.48	3	104	2	96	1.5e-25	83.7	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
2918239371	202	96.86	6	201	4	188	2.1e-53	175.6	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
2918239373	150	95.51	1	150	2	150	3.8e-65	212.9	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
2918239374	134	77.36	2	134	37	159	2.7e-26	86.4	COG1580	Flagellar basal body-associated protein FliL	159
2918239375	325	99.4	1	324	1	329	5.9e-99	325.9	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918239376	206	89.47	22	205	5	174	1.7e-51	168.8	COG3703	Cation transport regulator ChaC	190
2918239377	322	52.43	1	78	13	66	2.4e-09	29.6	COG0633	Ferredoxin	102
2918239377	322	95.72	85	318	9	254	4.5e-48	157.6	COG0543	NAD(P)H-flavin reductase	252
2918239378	488	99.59	1	488	1	481	0.0e+00	740.8	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
2918239379	419	98.82	1	419	4	420	0.0e+00	733.6	COG1158	Transcription termination factor Rho	422
2918239381	109	34.75	1	109	24	129	3.8e-29	96.8	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2918239382	500	99.39	8	493	3	494	0.0e+00	531.1	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
2918239383	753	98	58	751	6	690	0.0e+00	935.4	COG0855	Polyphosphate kinase	696
2918239384	336	98.79	6	336	3	328	0.0e+00	482.3	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
2918239385	214	88.46	1	188	18	201	3.1e-44	145.2	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2918239386	222	99.08	2	218	2	216	5.4e-111	363.7	COG3155	Enhancing lycopene biosynthesis protein 2	217
2918239387	150	97.33	1	150	2	147	3.1e-50	164.3	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
2918239393	472	98.04	10	472	2	452	2.2e-85	281.5	COG1538	Outer membrane protein TolC	457
2918239394	291	91.76	1	290	15	337	4.2e-77	247.6	COG1566	Multidrug resistance efflux pump	352
2918239396	695	97.38	8	688	9	676	5.2e-70	230.6	COG1289	Uncharacterized membrane protein YccC	674
2918239397	150	71.43	32	144	35	129	7.7e-17	55.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918239398	270	58.31	30	267	82	274	5.8e-23	76	COG0790	TPR repeat	292
2918239399	185	13.42	7	64	9	50	3.1e-07	15	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2918239399	185	15.97	98	185	263	312	3.1e-07	8.1	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2918239400	287	94.96	25	287	9	253	4.3e-66	217.3	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918239401	287	96.41	19	273	4	245	6.2e-85	278.9	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918239402	339	95.82	1	337	3	323	1.5e-49	163.4	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918239403	299	98.26	15	299	2	283	2.5e-88	290.6	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2918239405	9007	14.81	2878	2940	102	129	6.5e-19	2.1	COG2029	Uncharacterized protein	189
2918239405	9007	14.81	3998	4060	102	129	6.5e-19	2.1	COG2029	Uncharacterized protein	189
2918239405	9007	14.81	7127	7184	102	129	6.5e-19	2.3	COG2029	Uncharacterized protein	189
2918239405	9007	15.34	5566	5638	102	130	6.5e-19	2.6	COG2029	Uncharacterized protein	189
2918239405	9007	15.34	5791	5866	102	130	6.5e-19	2.6	COG2029	Uncharacterized protein	189
2918239405	9007	15.34	6016	6090	102	130	6.5e-19	2.4	COG2029	Uncharacterized protein	189
2918239405	9007	15.34	6233	6305	102	130	6.5e-19	2.6	COG2029	Uncharacterized protein	189
2918239405	9007	15.34	6461	6530	102	130	6.5e-19	2.4	COG2029	Uncharacterized protein	189
2918239405	9007	15.34	6683	6757	102	130	6.5e-19	2.4	COG2029	Uncharacterized protein	189
2918239405	9007	15.34	6902	6974	102	130	6.5e-19	2.4	COG2029	Uncharacterized protein	189
2918239405	9007	16.4	4889	4965	100	130	6.5e-19	1.7	COG2029	Uncharacterized protein	189
2918239405	9007	16.4	5114	5190	100	130	6.5e-19	1.7	COG2029	Uncharacterized protein	189
2918239405	9007	16.4	7350	7445	102	132	6.5e-19	3.4	COG2029	Uncharacterized protein	189
2918239405	9007	16.93	1987	2064	98	129	6.5e-19	2.2	COG2029	Uncharacterized protein	189
2918239405	9007	17.46	2652	2731	98	130	6.5e-19	2.3	COG2029	Uncharacterized protein	189
2918239405	9007	17.46	3097	3168	98	130	6.5e-19	2.3	COG2029	Uncharacterized protein	189
2918239405	9007	17.46	3322	3402	98	130	6.5e-19	3.5	COG2029	Uncharacterized protein	189
2918239405	9007	17.46	3547	3631	98	130	6.5e-19	3.5	COG2029	Uncharacterized protein	189
2918239405	9007	17.46	3772	3852	98	130	6.5e-19	3.5	COG2029	Uncharacterized protein	189
2918239405	9007	17.46	4217	4288	98	130	6.5e-19	2.3	COG2029	Uncharacterized protein	189
2918239405	9007	17.46	4437	4517	98	130	6.5e-19	3.5	COG2029	Uncharacterized protein	189
2918239405	9007	17.46	4662	4742	98	130	6.5e-19	3.5	COG2029	Uncharacterized protein	189
2918239405	9007	18.52	2206	2287	96	130	6.5e-19	4.3	COG2029	Uncharacterized protein	189
2918239405	9007	18.52	2431	2512	96	130	6.5e-19	4.3	COG2029	Uncharacterized protein	189
2918239405	9007	18.52	5336	5417	96	130	6.5e-19	4.3	COG2029	Uncharacterized protein	189
2918239406	445	90	3	425	38	451	4.0e-65	214.6	COG1538	Outer membrane protein TolC	457
2918239407	717	97.05	11	715	10	699	0.0e+00	634.7	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918239408	452	96.41	21	443	13	388	1.8e-43	143.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918239410	648	93.77	410	647	2	242	2.9e-53	174	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918239410	648	94.54	216	411	4	176	3.2e-25	82.5	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918239411	229	63.35	29	196	69	189	2.0e-37	123.1	COG3672	Predicted transglutaminase-like cysteine proteinase	191
2918239412	237	90.95	10	231	18	228	4.1e-48	157.9	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918239413	167	87.63	1	166	14	176	1.8e-37	123.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918239414	322	95.98	2	321	12	321	4.7e-86	282.9	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918239415	808	95.85	13	808	34	795	1.0e-115	382.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918239422	406	98.25	1	406	8	401	0.0e+00	521	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918239423	393	99	12	393	3	397	7.0e-115	378.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918239424	305	97.34	6	297	4	296	7.1e-56	184.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918239425	373	100	2	367	1	363	0.0e+00	510.2	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2918239426	106	30.85	1	106	98	209	6.3e-30	99.2	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2918239427	478	100	1	477	1	470	0.0e+00	732.7	COG1282	NAD/NADP transhydrogenase beta subunit	463
2918239428	497	99.61	1	496	2	510	0.0e+00	667	COG0427	Acyl-CoA hydrolase	501
2918239429	70	85.71	11	70	10	63	3.0e-15	50.2	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918239434	133	97.78	1	133	1	132	5.2e-37	121.2	COG3791	Uncharacterized conserved protein	133
2918239435	435	99.77	1	432	1	435	0.0e+00	629.2	COG2851	Mg2+/citrate symporter	433
2918239436	256	95.7	1	245	8	252	2.6e-80	263.6	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918239437	552	99.07	1	535	4	533	0.0e+00	579.3	COG1283	Na+/phosphate symporter	533
2918239438	468	92.91	6	428	15	420	1.8e-42	139.6	COG0612	Predicted Zn-dependent peptidase	438
2918239440	374	80.81	5	93	5	84	5.2e-07	23.2	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
2918239440	374	97.75	103	374	6	266	2.5e-89	293.2	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2918239441	264	96.2	2	263	5	257	1.2e-104	343.4	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
2918239442	312	81.62	1	311	1	302	2.1e-53	175.9	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2918239443	206	93.66	1	199	12	203	6.9e-52	170.3	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
2918239444	409	26.7	233	307	11	65	1.3e-84	4	COG2715	Spore maturation protein SpmA (function unknown)	206
2918239444	409	99.03	1	215	1	204	1.3e-84	277.2	COG2715	Spore maturation protein SpmA (function unknown)	206
2918239445	445	97.85	1	433	3	411	0.0e+00	534.5	COG1301	Na+/H+-dicarboxylate symporter	415
2918239447	53	98.15	1	53	1	53	3.3e-24	79.3	COG5487	Uncharacterized membrane protein YtjA, UPF0391 family	54
2918239449	273	35.03	18	95	128	196	7.0e-37	40.1	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918239449	273	36.04	183	269	123	193	7.0e-37	42.9	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918239449	273	38.07	96	180	118	192	7.0e-37	35.9	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918239450	448	97.43	6	448	4	458	0.0e+00	513.7	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918239451	588	72.08	243	588	104	387	1.1e-64	213.8	COG0642	Signal transduction histidine kinase	336
2918239451	588	88.1	162	241	6	79	2.1e-09	32.3	COG2770	HAMP domain	83
2918239452	538	97.54	9	533	7	522	0.0e+00	435.7	COG4943	Environmental sensor c-di-GMP phosphodiesterase, contains periplasmic CSS-motif sensor and cytoplasmic EAL domain	524
2918239453	258	88.51	15	257	29	259	1.5e-84	277.6	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
2918239454	650	95.63	442	649	7	181	8.9e-54	176.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918239455	284	97.67	40	273	6	256	1.7e-51	168.7	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918239456	211	73.49	3	209	66	248	1.3e-10	35.4	COG1651	Protein-disulfide isomerase	244
2918239458	205	51.11	125	205	44	112	1.3e-50	65.9	COG2863	Cytochrome c553	121
2918239458	205	98.52	1	124	2	134	1.3e-50	98.1	COG2863	Cytochrome c553	121
2918239459	123	66.67	3	122	41	124	1.2e-33	109.8	COG3245	Cytochrome c5	126
2918239460	210	97	9	206	4	197	1.2e-66	218.3	COG0218	GTP-binding protein EngB required for normal cell division	200
2918239462	921	92.35	2	305	12	313	1.4e-85	281.3	COG0258	5'-3' exonuclease	310
2918239462	921	99.83	312	921	2	597	0.0e+00	815.3	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
2918239464	316	95.82	1	315	5	325	1.3e-69	228.8	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2918239465	305	95.72	3	304	14	326	3.8e-107	352.3	COG4531	ABC-type Zn2+ transport system, periplasmic component/surface adhesin	318
2918239466	161	94.48	9	161	5	141	3.0e-37	121.9	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2918239467	257	98.82	2	237	3	253	6.6e-82	268.9	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
2918239468	260	93.48	1	260	11	268	6.4e-82	269.4	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2918239469	235	63.33	42	115	15	71	6.2e-04	12.3	COG1849	Uncharacterized protein	90
2918239470	714	98	28	538	5	495	0.0e+00	711.8	COG0753	Catalase	496
2918239471	335	99.41	1	335	1	338	0.0e+00	452.9	COG1135	ABC-type methionine transport system, ATPase component	339
2918239472	223	96.4	3	223	8	221	1.2e-91	300.3	COG2011	ABC-type methionine transport system, permease component	222
2918239473	256	94.81	1	256	15	270	2.0e-106	349.4	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
2918239474	210	94.76	3	210	10	208	6.2e-51	167.2	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
2918239475	300	93.81	2	299	15	302	1.4e-110	363.8	COG0109	Polyprenyltransferase (heme O synthase)	304
2918239476	355	92.08	2	336	21	334	4.2e-77	253.2	COG1612	Heme A synthase	323
2918239478	247	95.28	1	242	10	251	3.2e-42	138.8	COG3346	Cytochrome oxidase assembly protein ShyY1	252
2918239480	295	96.24	56	295	6	210	1.3e-71	234.3	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918239481	188	90.15	5	186	17	199	6.2e-64	209.4	COG3175	Cytochrome c oxidase assembly protein Cox11	195
2918239482	530	89.98	16	530	6	517	0.0e+00	718.3	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2918239483	375	89.37	6	279	12	238	4.7e-72	236.2	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2918239486	508	90.41	2	507	20	528	1.8e-116	383.9	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2918239487	240	98.08	20	227	2	205	3.0e-69	227.3	COG0288	Carbonic anhydrase	207
2918239488	352	97.31	38	343	5	293	1.2e-99	327.5	COG1533	DNA repair photolyase	297
2918239489	674	96.93	1	674	20	681	2.7e-118	390.5	COG0339	Zn-dependent oligopeptidase	683
2918239490	93	94.2	1	87	5	69	2.4e-29	95.6	COG3529	Predicted nucleic-acid-binding protein, contains Zn-ribbon domain	66
2918239491	683	98.83	1	679	8	682	0.0e+00	937.4	COG0339	Zn-dependent oligopeptidase	683
2918239492	182	94.92	1	180	3	170	6.1e-65	212.2	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2918239493	216	97.75	1	215	2	218	5.6e-45	148.2	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918239494	332	86.97	1	326	47	373	0.0e+00	502.7	COG4324	Predicted aminopeptidase	376
2918239498	141	97.2	2	140	4	142	1.2e-36	120.3	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2918239499	334	96.21	15	332	8	337	7.3e-68	223.4	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918239501	71	98.59	1	71	1	70	1.9e-35	115.8	COG3360	Flavin-binding protein dodecin	71
2918239502	107	94.23	1	106	7	104	1.2e-19	65.5	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2918239503	298	98.34	6	297	2	297	1.1e-52	174.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918239504	405	98.99	8	404	3	394	0.0e+00	679.1	COG0133	Tryptophan synthase beta chain	396
2918239505	269	99.62	1	266	1	264	3.0e-103	338.9	COG0159	Tryptophan synthase alpha chain	265
2918239506	110	84.17	1	109	7	107	2.8e-30	99.2	COG3805	Aromatic ring-cleaving dioxygenase	120
2918239508	521	94.49	2	516	3	534	2.3e-123	406.8	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2918239509	274	96.83	1	273	8	282	8.0e-85	278.7	COG0169	Shikimate 5-dehydrogenase	283
2918239510	303	98.68	1	301	5	303	0.0e+00	479.9	COG0408	Coproporphyrinogen III oxidase	303
2918239511	325	99.4	2	325	2	330	1.3e-101	334.7	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918239512	67	14.12	16	64	95	130	1.9e-03	11.1	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
2918239515	185	86.79	2	185	15	198	5.9e-55	180	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
2918239516	288	80.78	1	287	68	357	8.7e-109	358.2	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
2918239517	168	99.41	1	165	1	168	1.8e-67	220.5	COG0242	Peptide deformylase	168
2918239518	310	98.05	1	306	2	303	1.9e-121	399.5	COG0223	Methionyl-tRNA formyltransferase	307
2918239519	436	99.72	89	432	1	357	7.2e-101	332.5	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
2918239520	457	98.21	232	452	1	220	1.3e-109	126	COG0569	Trk K+ transport system, NAD-binding component	225
2918239520	457	98.66	1	228	1	221	1.3e-109	239.3	COG0569	Trk K+ transport system, NAD-binding component	225
2918239521	105	19.18	2	105	362	454	5.9e-10	33.1	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2918239522	295	95.13	1	295	15	307	1.1e-84	278.6	COG1560	Lauroyl/myristoyl acyltransferase	308
2918239523	183	98.4	1	183	1	185	2.9e-74	243.2	COG2818	3-methyladenine DNA glycosylase Tag	188
2918239524	315	97.99	5	302	4	295	0.0e+00	545.3	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
2918239525	684	99.71	1	684	1	689	0.0e+00	857.6	COG0751	Glycyl-tRNA synthetase, beta subunit	691
2918239526	175	93.99	1	175	6	177	5.8e-56	183.2	COG0241	Histidinol phosphatase or a related phosphatase	181
2918239527	256	86.97	12	255	11	237	4.3e-48	158.2	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918239528	539	47.26	240	534	8	188	2.7e-34	13.3	COG0477	MFS family permease	338
2918239528	539	63.45	21	282	2	244	2.7e-34	102.2	COG0477	MFS family permease	338
2918239529	549	97.36	2	546	6	558	0.0e+00	511.3	COG2303	Choline dehydrogenase or related flavoprotein	542
2918239530	295	99.34	2	291	1	299	1.3e-56	187.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918239531	271	95.75	1	271	8	255	1.5e-40	133.6	COG0730	Uncharacterized membrane protein YfcA	258
2918239532	294	90.38	2	272	19	253	3.3e-48	158.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918239534	806	99.69	2	806	2	640	0.0e+00	978.8	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
2918239535	361	97.8	1	355	9	363	3.3e-108	356.4	COG1195	Recombinational DNA repair ATPase RecF	363
2918239536	367	100	1	367	1	365	3.5e-123	405.9	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
2918239537	508	99.77	6	504	1	432	0.0e+00	619.1	COG0593	Chromosomal replication initiation ATPase DnaA	408
2918239538	44	100	1	44	1	44	5.7e-27	88.1	COG0230	Ribosomal protein L34	44
2918239539	133	94.92	5	122	2	113	2.3e-32	105.9	COG0594	RNase P protein component	117
2918239540	561	94.29	267	561	2	298	1.2e-109	361	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
2918239541	456	99.34	2	456	4	454	0.0e+00	557.6	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
2918239542	630	99.2	3	624	3	621	0.0e+00	958.6	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
2918239543	216	98.6	9	216	2	213	2.1e-66	217.9	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
2918239544	263	98.86	1	258	1	261	1.5e-88	291.5	COG1192	Cellulose biosynthesis protein BcsQ	259
2918239545	290	98.11	33	285	4	262	3.2e-73	241.4	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918239546	138	87.5	12	133	15	126	1.3e-32	107.1	COG3312	FoF1-type ATP synthase assembly protein I	128
2918239547	289	97.22	1	288	7	251	1.1e-86	284.8	COG0356	FoF1-type ATP synthase, membrane subunit a	246
2918239548	85	91.25	1	78	8	80	4.4e-22	72.5	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
2918239549	156	96.27	1	156	3	157	2.6e-51	167.9	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2918239550	178	100	1	177	1	178	1.4e-56	185.7	COG0712	FoF1-type ATP synthase, delta subunit	178
2918239551	514	99.21	2	514	2	501	0.0e+00	793.6	COG0056	FoF1-type ATP synthase, alpha subunit	504
2918239552	248	87.85	1	248	35	287	8.7e-95	312.1	COG0224	FoF1-type ATP synthase, gamma subunit	287
2918239553	458	99.15	1	458	1	464	0.0e+00	798.6	COG0055	FoF1-type ATP synthase, beta subunit	468
2918239554	139	99.26	1	135	1	134	1.1e-43	142.7	COG0355	FoF1-type ATP synthase, epsilon subunit	135
2918239555	455	99.35	1	455	2	457	0.0e+00	632.3	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
2918239556	258	98.82	4	253	3	253	1.7e-73	241.6	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2918239557	611	100	1	611	1	615	0.0e+00	808.6	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
2918239562	125	35.82	1	125	206	325	1.2e-12	42.8	COG0582	Integrase	309
2918239570	449	67.36	68	356	32	289	1.2e-05	17.6	COG1474	Cdc6-related protein, AAA superfamily ATPase	366
2918239571	328	45.54	114	265	49	145	1.4e-08	28.5	COG2856	Zn-dependent peptidase ImmA, M78 family	213
2918239573	106	61.54	1	95	4	75	1.4e-15	52.2	COG2963	Transposase and inactivated derivatives	116
2918239574	111	57.67	4	104	40	133	2.7e-15	50.7	COG3436	Transposase	157
2918239575	511	98.77	96	257	3	163	2.0e-40	132.3	COG3436	Transposase	157
2918239576	311	8.49	13	91	77	107	7.8e-09	5.3	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918239576	311	23.84	139	283	158	244	7.8e-09	21	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918239578	394	96.15	91	376	10	284	1.3e-105	346.8	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2918239579	479	99.59	47	479	2	484	7.8e-100	329.3	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918239581	295	96.21	2	295	5	283	1.4e-65	215.7	COG1469	GTP cyclohydrolase FolE2	289
2918239583	402	99.69	5	375	1	325	4.0e-110	362.7	COG0523	GTPase, G3E family	323
2918239585	323	96.32	5	321	1	314	9.6e-43	139.7	COG0523	GTPase, G3E family	323
2918239587	290	99.29	5	289	2	280	7.0e-95	311.8	COG2240	Pyridoxal/pyridoxine/pyridoxamine kinase	281
2918239588	161	93.63	1	151	10	156	4.6e-55	180	COG1607	Acyl-CoA hydrolase	157
2918239589	586	95.5	1	399	3	384	2.3e-111	367	COG0475	Kef-type K+ transport system, membrane component KefB	397
2918239591	284	98.22	29	284	5	280	2.0e-58	192.7	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
2918239592	727	98.81	11	655	2	664	0.0e+00	768.4	COG0210	Superfamily I DNA or RNA helicase	655
2918239593	463	95.27	1	463	22	484	0.0e+00	618.2	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
2918239594	288	98.58	1	278	4	281	5.6e-83	272.7	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918239596	320	98.01	8	302	1	295	4.0e-64	211.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918239597	471	71.21	1	470	2	461	0.0e+00	644	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918239598	602	48.98	471	602	75	146	7.8e-28	91.8	COG0511	Biotin carboxyl carrier protein	140
2918239598	602	94.32	1	464	3	450	0.0e+00	735.1	COG5016	Pyruvate/oxaloacetate carboxyltransferase	472
2918239599	435	76.69	44	391	27	332	6.2e-20	65.3	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
2918239600	92	69.57	27	85	7	54	8.7e-07	22.9	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2918239601	273	89.91	28	271	21	225	8.3e-69	226	COG0765	ABC-type amino acid transport system, permease component	222
2918239602	273	93.99	1	273	10	275	2.1e-46	152.9	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918239603	299	96.67	1	299	7	296	2.2e-59	195.5	COG2040	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)	300
2918239604	224	95.19	9	196	8	185	8.0e-29	95.4	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918239605	148	78.4	9	146	24	150	1.6e-13	45.6	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918239606	209	98.1	1	208	1	206	5.4e-71	232.9	COG2808	Predicted FMN-binding regulatory protein PaiB	209
2918239607	508	98.25	19	508	4	451	0.0e+00	435.9	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918239608	367	99.47	1	367	3	378	8.7e-112	368.3	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918239609	348	91.07	4	348	3	318	4.1e-99	326.3	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2918239610	330	77.27	208	330	22	123	1.0e-23	77.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918239611	474	98.3	4	473	3	465	0.0e+00	742.2	COG1027	Aspartate ammonia-lyase	471
2918239612	309	90.7	3	297	4	276	9.1e-46	151.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918239613	163	95.73	1	163	5	161	1.2e-73	240.6	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
2918239614	360	96.81	1	359	3	366	5.9e-128	421.2	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
2918239615	81	98.78	1	81	1	81	1.5e-21	70.9	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
2918239616	177	94.58	1	177	9	165	3.7e-62	203.9	COG3495	Uncharacterized protein	166
2918239617	298	91.41	2	298	23	288	9.8e-89	291.7	COG0676	D-hexose-6-phosphate mutarotase	287
2918239618	132	80.25	3	132	5	130	2.4e-43	141.9	COG1607	Acyl-CoA hydrolase	157
2918239619	429	49.61	242	429	5	194	3.1e-30	14	COG0477	MFS family permease	338
2918239619	429	71.8	17	284	4	278	3.1e-30	90.6	COG0477	MFS family permease	338
2918239623	332	96.92	1	314	10	324	7.5e-70	230.1	COG0226	ABC-type phosphate transport system, periplasmic component	318
2918239624	762	99.05	18	762	8	733	0.0e+00	1032.5	COG4590	ABC-type uncharacterized transport system, permease component	733
2918239625	556	79.3	266	551	65	313	1.4e-46	153.5	COG0573	ABC-type phosphate transport system, permease component	310
2918239625	556	98.96	1	288	4	289	3.5e-109	358.8	COG4985	ABC-type phosphate transport system, auxiliary component	289
2918239626	277	98.82	24	277	4	254	4.5e-130	426.9	COG1117	ABC-type phosphate transport system, ATPase component	253
2918239627	256	95.1	3	239	6	238	1.9e-70	231.3	COG0704	Phosphate uptake regulator	240
2918239628	295	93.23	1	129	6	129	4.2e-29	94	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918239629	375	85.56	60	302	25	267	5.8e-18	59.2	COG2801	Transposase InsO and inactivated derivatives	232
2918239630	298	43.35	39	292	162	298	2.0e-35	117.7	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2918239631	446	97.72	13	446	4	431	2.0e-117	387	COG1253	Hemolysin or related protein, contains CBS domains	429
2918239632	435	86.55	25	431	46	386	6.9e-70	230.7	COG0642	Signal transduction histidine kinase	336
2918239633	229	99.14	4	229	2	231	4.3e-85	279.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918239634	123	79.71	2	123	29	138	1.9e-47	155	COG4315	Predicted lipoprotein with conserved Yx(FWY)xxD motif (function unknown)	138
2918239635	296	98.62	7	294	4	289	3.1e-87	286.7	COG0382	4-hydroxybenzoate polyprenyltransferase	289
2918239636	185	91.53	13	182	14	175	4.2e-40	131.4	COG3161	4-hydroxybenzoate synthetase (chorismate-pyruvate lyase)	174
2918239637	55	96.36	1	55	1	53	9.2e-30	97	COG1773	Rubredoxin	55
2918239638	382	37.83	1	314	5	307	1.1e-51	170.3	COG1251	NAD(P)H-nitrite reductase, large subunit	793
2918239639	101	95.74	1	92	2	91	6.5e-33	107.3	COG0776	Bacterial nucleoid DNA-binding protein	94
2918239641	467	94.84	1	153	4	150	2.4e-13	44.2	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
2918239641	467	98.96	172	465	2	287	2.8e-84	276.5	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
2918239642	692	98.67	1	685	9	677	0.0e+00	874.9	COG1200	RecG-like helicase	677
2918239643	308	97.01	1	300	1	292	1.4e-66	219.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918239644	243	94.53	5	241	14	272	1.8e-34	114.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2918239645	142	92.09	1	140	10	137	1.7e-45	149	COG0848	Biopolymer transport protein ExbD	137
2918239646	322	99.54	99	309	1	215	1.1e-62	206	COG0811	Biopolymer transport protein ExbB/TolQ	216
2918239647	285	96.26	1	285	5	313	1.6e-36	121	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918239649	126	97.06	1	126	3	134	3.5e-41	134.8	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918239650	702	99.03	1	700	7	723	0.0e+00	903.4	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2918239651	87	91.89	1	73	1	68	5.5e-26	84.3	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
2918239652	291	97.01	5	290	5	296	7.3e-49	161.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918239653	460	98.21	10	459	8	445	0.0e+00	433.4	COG0174	Glutamine synthetase	443
2918239654	257	97.95	4	249	4	242	1.7e-71	234.9	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
2918239655	515	91.87	20	509	11	462	5.9e-30	98.4	COG0531	Amino acid transporter	466
2918239656	206	95.9	1	197	3	189	1.2e-79	260.8	COG0194	Guanylate kinase	191
2918239657	283	98.62	1	283	5	290	1.7e-101	334.2	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
2918239658	240	96.54	1	239	9	231	8.2e-100	327.3	COG0689	Ribonuclease PH	230
2918239659	254	97.68	1	250	6	258	4.4e-66	217.3	COG0708	Exonuclease III	261
2918239660	213	99.51	3	211	2	203	9.0e-67	219.1	COG0461	Orotate phosphoribosyltransferase	201
2918239663	219	99.07	5	219	3	216	2.1e-104	342.2	COG4380	Uncharacterized protein	216
2918239664	118	95.87	1	117	6	121	3.3e-52	170.2	COG4259	Uncharacterized protein	121
2918239665	227	92.55	4	227	6	241	3.0e-77	253.9	COG1462	Curli biogenesis system outer membrane secretion channel CsgG	252
2918239666	302	99.25	26	297	2	264	5.7e-109	357.7	COG0548	Acetylglutamate kinase	265
2918239667	465	95.61	8	458	11	467	0.0e+00	435.6	COG1109	Phosphomannomutase	464
2918239668	151	98.66	1	151	2	148	2.1e-57	187.4	COG0756	dUTPase	148
2918239669	403	99.5	3	400	2	400	0.0e+00	451.7	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
2918239670	226	100	1	224	1	224	1.9e-80	263.9	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
2918239671	530	95.67	1	529	16	568	8.5e-115	379.2	COG0747	ABC-type transport system, periplasmic component	556
2918239672	66	79.22	1	65	14	74	5.7e-28	91.5	COG0227	Ribosomal protein L28	77
2918239673	51	96.08	1	49	3	51	9.3e-26	84.4	COG0267	Ribosomal protein L33	50
2918239675	119	99.14	1	117	1	115	6.5e-38	123.7	COG3450	Predicted enzyme of the cupin superfamily	116
2918239676	497	98.75	20	497	3	475	0.0e+00	579.1	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918239677	379	48.04	194	378	6	189	7.0e-18	32.9	COG0477	MFS family permease	338
2918239677	379	69.71	1	212	5	271	7.0e-18	29.1	COG0477	MFS family permease	338
2918239678	518	78.35	20	510	57	436	8.6e-91	299.3	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918239679	476	98.46	1	471	4	452	0.0e+00	459.5	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918239681	76	52.38	19	75	30	62	3.9e-11	37.1	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918239682	430	99.23	27	412	2	386	1.8e-79	262.2	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918239684	162	94.3	6	159	3	151	1.6e-46	152.6	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918239685	433	96.65	1	423	5	379	1.2e-89	295.5	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918239686	357	99.45	1	356	2	363	1.4e-128	423.3	COG0787	Alanine racemase	360
2918239687	182	56.15	2	138	2	74	3.6e-18	60.8	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918239688	140	92.86	7	140	7	123	5.7e-35	114.8	COG3245	Cytochrome c5	126
2918239689	620	99.22	29	547	3	509	4.2e-91	294.7	COG0427	Acyl-CoA hydrolase	501
2918239690	190	96.65	1	180	6	178	6.8e-50	163.4	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
2918239691	669	98.96	2	649	1	664	0.0e+00	694.1	COG0210	Superfamily I DNA or RNA helicase	655
2918239692	554	64.25	84	550	216	641	2.3e-110	363.9	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918239693	462	96.3	2	456	15	457	6.0e-91	299.4	COG0534	Na+-driven multidrug efflux pump	455
2918239694	309	98.34	6	299	2	297	1.2e-54	180.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918239695	659	81.88	168	657	78	425	1.2e-99	329.1	COG0840	Methyl-accepting chemotaxis protein	408
2918239696	464	98.26	3	464	3	453	0.0e+00	628.9	COG5383	Uncharacterized metalloenzyme YdcJ, glyoxalase superfamily	295
2918239697	296	97.34	7	296	3	295	3.9e-65	215	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918239698	496	96.45	7	486	16	477	0.0e+00	477.9	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918239699	428	97.42	25	408	2	379	2.2e-71	235.5	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918239700	475	79.82	13	339	39	311	2.1e-41	136.4	COG0668	Small-conductance mechanosensitive channel	316
2918239701	209	94.17	9	203	2	195	4.3e-25	82	COG1335	Nicotinamidase-related amidase	205
2918239702	188	89.74	2	188	8	182	1.6e-36	119.9	COG3224	Antibiotic biosynthesis monooxygenase (ABM) superfamily enzyme	195
2918239703	660	99.44	46	582	3	534	0.0e+00	583.2	COG1574	Predicted amidohydrolase YtcJ	535
2918239706	527	49.61	216	432	12	201	2.5e-19	23.1	COG0477	MFS family permease	338
2918239706	527	57.58	428	513	4	60	1.6e-05	18.6	COG1359	Quinol monooxygenase YgiN	100
2918239706	527	63.19	9	253	3	244	2.5e-19	45.8	COG0477	MFS family permease	338
2918239708	303	98.34	2	301	2	297	4.6e-65	214.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918239709	209	88.35	9	202	2	183	9.2e-25	79.4	COG1335	Nicotinamidase-related amidase	205
2918239712	595	83.41	397	591	27	212	2.6e-26	87.5	COG1226	Voltage-gated potassium channel Kch	212
2918239712	595	97.25	1	397	2	390	1.1e-104	344.7	COG0475	Kef-type K+ transport system, membrane component KefB	397
2918239713	324	96.92	1	323	5	319	1.8e-94	310.8	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918239714	121	14.77	6	61	269	316	6.9e-28	33.1	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918239714	121	24.31	37	118	245	323	6.9e-28	66.8	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918239715	208	30.58	102	172	133	195	2.7e-25	41.8	COG1335	Nicotinamidase-related amidase	205
2918239715	208	51.46	9	109	2	107	2.7e-25	43	COG1335	Nicotinamidase-related amidase	205
2918239716	1698	80.32	301	1068	2	703	1.8e-77	255.4	COG3899	Predicted ATPase	849
2918239716	1698	82.23	1351	1698	64	387	8.0e-53	175	COG0642	Signal transduction histidine kinase	336
2918239717	333	58.78	2	119	20	106	2.9e-24	79.2	COG3710	DNA-binding winged helix-turn-helix (wHTH) domain	148
2918239717	333	96.04	123	323	6	199	3.1e-62	203.8	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918239718	128	58.42	7	128	4	121	4.5e-32	105.6	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918239719	433	97.38	9	432	9	417	4.5e-36	118.4	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
2918239720	304	97.34	3	299	5	297	9.0e-74	243.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918239721	440	95.45	1	419	5	403	0.0e+00	473.9	COG1301	Na+/H+-dicarboxylate symporter	415
2918239722	299	96.66	2	298	4	292	5.2e-89	292.5	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
2918239723	202	95.68	1	189	2	178	4.7e-70	229	COG1838	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain	184
2918239724	136	88.19	3	131	9	135	8.4e-17	56.3	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918239725	495	98.78	15	495	1	486	0.0e+00	631.8	COG0606	Predicted ATPase with chaperone activity	490
2918239726	96	87.38	1	95	11	100	2.6e-28	92.7	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
2918239727	112	100	1	112	1	112	5.8e-50	163	COG0347	Nitrogen regulatory protein PII	112
2918239728	440	98.3	30	440	2	406	0.0e+00	542.3	COG0004	Ammonia channel protein AmtB	409
2918239730	231	99.13	1	230	2	230	4.7e-40	132.3	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918239731	299	97.99	1	294	6	298	1.4e-125	412.9	COG4973	Site-specific recombinase XerC	299
2918239732	236	99.54	12	230	1	217	2.8e-71	234	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
2918239733	276	99.26	3	276	2	270	8.0e-104	341.2	COG0253	Diaminopimelate epimerase	272
2918239734	415	99.49	1	389	3	395	0.0e+00	461.2	COG0019	Diaminopimelate decarboxylase	394
2918239735	67	79.31	1	67	1	46	1.9e-14	46.5	COG5567	Predicted small periplasmic lipoprotein YifL (function unknown0	58
2918239736	110	98.11	3	108	2	105	2.0e-32	105.8	COG1965	Iron-binding protein CyaY, frataxin homolog	106
2918239737	70	70.27	15	70	5	56	3.3e-16	53.7	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
2918239739	136	64.47	11	127	55	152	7.6e-23	75.6	COG0782	Transcription elongation factor, GreA/GreB family	151
2918239740	954	96.25	16	861	2	822	0.0e+00	874.4	COG3072	Adenylate cyclase	853
2918239743	219	94.42	2	210	1	203	1.3e-29	98	COG0625	Glutathione S-transferase	211
2918239744	464	98.91	5	463	2	455	0.0e+00	676	COG0165	Argininosuccinate lyase	459
2918239745	249	98.79	1	248	2	246	6.0e-56	184.4	COG3279	DNA-binding response regulator, LytR/AlgR family	244
2918239746	313	99.02	3	308	2	305	1.4e-119	393.1	COG0181	Porphobilinogen deaminase	307
2918239747	255	95.6	3	251	2	240	1.5e-43	143.2	COG1587	Uroporphyrinogen-III synthase	248
2918239748	366	84.85	2	363	29	364	2.6e-67	221.9	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
2918239749	412	97.75	1	403	1	391	7.0e-106	348.5	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
2918239750	168	91.91	1	164	12	170	1.7e-19	64.9	COG1495	Disulfide bond formation protein DsbB	170
2918239751	156	95.68	1	156	1	155	3.8e-44	144.8	COG3160	Regulator of sigma D	162
2918239752	221	95.63	20	220	9	205	4.7e-51	168	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
2918239754	160	65.24	2	133	14	120	9.2e-23	75	COG5589	Uncharacterized protein	164
2918239755	636	98.88	1	521	3	531	0.0e+00	593	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918239756	195	44.15	12	192	70	220	2.3e-22	74	COG0668	Small-conductance mechanosensitive channel	316
2918239758	208	98.56	1	205	3	207	8.9e-56	182.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918239759	152	41.76	7	124	8	78	1.9e-03	12.3	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
2918239760	152	94.19	1	152	4	149	1.8e-27	90.4	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
2918239763	145	92.64	4	124	13	163	7.7e-29	95.5	COG0517	CBS domain	117
2918239765	480	98.75	11	480	2	474	0.0e+00	627.6	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918239767	426	96.41	1	426	16	445	0.0e+00	541.6	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2918239768	423	60.99	2	140	12	122	2.1e-04	14.8	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918239768	423	89.97	141	414	16	275	1.9e-38	126.1	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
2918239772	329	96.17	149	328	6	181	1.2e-52	172.3	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918239773	393	85.52	2	256	42	289	1.5e-90	297.6	COG1398	Fatty-acid desaturase	289
2918239775	631	64.25	98	630	216	641	1.7e-121	400.6	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918239776	214	95.05	1	214	12	222	1.2e-89	294	COG2011	ABC-type methionine transport system, permease component	222
2918239777	369	99.12	32	367	3	339	4.7e-125	411.8	COG1135	ABC-type methionine transport system, ATPase component	339
2918239778	266	94.81	1	264	11	266	1.4e-75	248.3	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
2918239779	464	97.38	10	420	9	342	8.7e-97	318.7	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918239780	393	92.98	5	387	16	386	1.2e-66	219.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918239781	413	97.24	12	409	9	396	6.8e-66	217.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918239782	253	99.17	1	246	2	241	3.8e-107	351.3	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918239783	222	92.98	2	219	15	226	1.3e-84	277.8	COG0765	ABC-type amino acid transport system, permease component	222
2918239784	264	93.99	1	264	9	274	3.9e-72	237.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918239785	310	79.59	126	305	8	163	7.3e-51	166.4	COG1045	Serine acetyltransferase	194
2918239786	665	98.52	5	563	7	537	0.0e+00	663	COG1292	Choline-glycine betaine transporter	537
2918239787	362	93.33	1	355	15	378	3.4e-51	168.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918239788	355	94.87	2	354	14	383	2.5e-45	149.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918239789	1018	99.9	6	1010	1	1013	0.0e+00	925.4	COG0841	Multidrug efflux pump subunit AcrB	1009
2918239790	60	88.89	4	60	5	52	1.1e-25	83.4	COG5583	Uncharacterized protein	54
2918239791	335	91.12	2	335	29	346	0.0e+00	518.2	COG1613	ABC-type sulfate transport system, periplasmic component	348
2918239792	272	97.81	1	272	3	270	9.0e-111	363.6	COG0555	ABC-type sulfate transport system, permease component	274
2918239793	290	95.47	5	290	8	281	0.0e+00	443.1	COG4208	ABC-type sulfate transport system, permease component	287
2918239794	329	99.14	1	328	1	347	0.0e+00	448	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
2918239795	267	80.29	68	267	54	273	1.2e-28	87.8	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2918239796	240	95.37	5	219	8	213	2.8e-59	195.1	COG0811	Biopolymer transport protein ExbB/TolQ	216
2918239797	133	97.12	1	133	1	135	2.6e-41	135.4	COG0848	Biopolymer transport protein ExbD	137
2918239800	193	98.9	4	187	2	180	7.3e-64	209.2	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
2918239801	314	68.28	3	313	86	382	5.4e-95	313.2	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain	403
2918239802	261	98.52	1	261	5	270	4.5e-107	351.6	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
2918239803	788	98.07	1	786	3	766	0.0e+00	609.4	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
2918239804	188	88.42	14	188	8	175	1.2e-50	166.5	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918239806	308	90.91	47	308	22	301	3.8e-46	151.7	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918239808	207	87.6	1	207	27	245	2.1e-37	123.7	COG3751	Proline 4-hydroxylase (includes Rps23 Pro-64 3,4-dihydroxylase Tpa1), contains SM-20 domain	252
2918239809	165	96.15	4	161	4	153	1.3e-50	165.6	COG1683	Uncharacterized conserved protein YbbK, DUF523 family	156
2918239810	162	13.43	96	160	237	274	2.0e-20	18.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918239810	162	34.28	1	118	11	107	2.0e-20	49.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918239813	409	99.08	8	336	2	324	5.9e-109	358.2	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918239814	473	99.57	17	473	2	468	7.3e-119	392	COG0277	FAD/FMN-containing dehydrogenase	459
2918239815	221	77.66	3	221	58	269	2.2e-65	215.3	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918239816	308	94.64	1	308	13	312	1.1e-81	268.8	COG3204	Uncharacterized protein YjiK	316
2918239817	303	87.38	1	303	35	311	3.7e-103	339.3	COG3204	Uncharacterized protein YjiK	316
2918239818	224	99.56	1	223	1	227	2.3e-79	260.2	COG0120	Ribose 5-phosphate isomerase	227
2918239819	504	98.55	1	339	6	346	0.0e+00	449.5	COG1171	Threonine dehydratase	347
2918239820	141	98.06	1	141	2	153	1.6e-25	79.9	COG5528	Uncharacterized membrane protein	155
2918239821	218	93.4	1	218	5	202	9.3e-58	189.6	COG0560	Phosphoserine phosphatase	212
2918239822	168	89.53	9	166	13	166	1.8e-23	77.7	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918239823	759	99.87	1	755	1	755	0.0e+00	1057.6	COG3605	Signal transduction protein containing GAF and PtsI domains	756
2918239824	248	94.44	1	248	1	255	4.6e-88	289.6	COG3332	Uncharacterized conserved protein, contains NRDE domain	270
2918239825	260	95.75	1	260	5	252	3.0e-53	175	COG0730	Uncharacterized membrane protein YfcA	258
2918239826	269	95.49	1	269	6	280	1.3e-99	327.3	COG0682	Prolipoprotein diacylglyceryltransferase	287
2918239827	323	99.27	1	323	3	273	8.5e-75	245.4	COG0207	Thymidylate synthase	268
2918239828	147	94.7	1	118	1	125	2.8e-32	106.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918239829	750	98.91	54	750	5	727	0.0e+00	754.1	COG2217	Cation transport ATPase	713
2918239830	289	94.68	1	287	4	288	1.0e-57	190.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918239831	354	98.3	8	354	5	351	1.0e-116	384.4	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918239832	570	96.69	20	561	14	539	5.4e-115	379.2	COG1178	ABC-type Fe3+ transport system, permease component	540
2918239833	341	98.34	40	334	2	297	5.2e-63	207.5	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918239836	172	97.65	6	172	2	167	4.5e-51	167.5	COG0262	Dihydrofolate reductase	167
2918239837	463	99.13	1	458	3	456	0.0e+00	685.4	COG1823	L-cystine uptake protein TcyP, sodium:dicarboxylate symporter family	458
2918239839	613	97.92	1	610	10	575	0.0e+00	790.9	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918239840	351	71.59	15	351	127	451	4.5e-103	339.6	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
2918239841	398	99.49	6	395	2	392	3.2e-118	389.4	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
2918239842	290	89.27	3	289	21	278	1.6e-79	260.9	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
2918239843	270	100	1	270	1	274	4.3e-99	326.1	COG0266	Formamidopyrimidine-DNA glycosylase	273
2918239844	560	97.43	12	559	14	544	0.0e+00	545.6	COG0405	Gamma-glutamyltranspeptidase	539
2918239845	83	60.48	1	76	39	113	5.2e-15	49.8	COG1145	Ferredoxin	99
2918239846	159	98.11	1	158	3	158	1.2e-68	224.4	COG0669	Phosphopantetheine adenylyltransferase	159
2918239849	221	69.86	1	210	13	158	1.5e-22	75.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918239850	284	96.52	1	284	9	285	7.4e-86	282.3	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2918239851	330	93.1	3	329	18	341	5.3e-109	358.4	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
2918239852	453	96.8	17	447	13	435	2.9e-60	198.5	COG0612	Predicted Zn-dependent peptidase	438
2918239853	444	97.25	11	443	7	431	6.6e-91	299.3	COG0612	Predicted Zn-dependent peptidase	438
2918239854	200	98.4	20	200	2	186	1.3e-58	192.1	COG0742	16S rRNA G966 N2-methylase RsmD	187
2918239855	498	97.25	57	483	10	434	4.0e-87	286.9	COG0612	Predicted Zn-dependent peptidase	438
2918239856	451	96.34	14	451	12	432	1.3e-111	367.7	COG0612	Predicted Zn-dependent peptidase	438
2918239857	530	87.78	182	525	44	359	0.0e+00	431.1	COG0552	Signal recognition particle GTPase	340
2918239858	223	98.65	1	223	1	220	2.4e-96	316.2	COG2884	ABC-type ATPase involved in cell division	223
2918239859	341	99.33	42	341	2	296	8.2e-84	275.5	COG2177	Cell division protein FtsX	297
2918239860	284	77.42	2	283	66	329	5.4e-92	303.2	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918239861	236	30.86	1	235	40	259	4.9e-71	234.6	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2918239862	123	95.16	1	123	3	120	3.2e-41	135	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
2918239863	66	97.06	1	66	3	68	5.3e-26	85.2	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
2918239864	264	97.71	3	264	4	259	2.9e-116	381.7	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
2918239865	240	98.24	18	240	2	224	5.2e-78	256.1	COG0220	tRNA G46 methylase TrmB	227
2918239867	404	90.48	10	404	35	414	4.0e-129	425.3	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
2918239868	197	97.44	3	196	2	191	7.4e-67	219	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
2918239870	206	51.61	1	200	51	194	2.5e-13	45.2	COG0500	SAM-dependent methyltransferase	257
2918239871	379	98.66	1	377	4	370	0.0e+00	491.2	COG2021	Homoserine acetyltransferase	368
2918239872	196	84.38	1	94	9	89	2.0e-34	44.9	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
2918239872	196	90.62	93	187	6	92	2.0e-34	74	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
2918239873	272	99.25	3	269	2	267	8.4e-93	305.1	COG0345	Pyrroline-5-carboxylate reductase	266
2918239874	228	99.56	2	225	2	229	7.5e-86	281.9	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
2918239875	332	93.77	1	332	3	333	2.5e-130	429.1	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
2918239876	213	75.9	6	196	58	246	1.5e-50	167.2	COG0791	Cell wall-associated hydrolase, NlpC family	197
2918239877	139	52.58	81	139	12	62	6.1e-22	21.1	COG2314	Uncharacterized membrane protein YozV, TM2 domain	95
2918239877	139	78.35	9	89	6	81	6.1e-22	59.1	COG2314	Uncharacterized membrane protein YozV, TM2 domain	95
2918239878	232	85.02	1	230	39	265	1.7e-40	133.9	COG3087	Cell division protein FtsN	264
2918239879	578	99.48	1	578	4	581	0.0e+00	638.6	COG0018	Arginyl-tRNA synthetase	577
2918239880	739	99.59	3	738	3	733	0.0e+00	858.7	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
2918239881	71	97.33	1	71	1	73	1.4e-31	103	COG0254	Ribosomal protein L31	75
2918239882	250	78.87	2	164	33	185	8.7e-30	97.4	COG1525	Endonuclease YncB, thermonuclease family	192
2918239883	422	91.63	1	419	17	421	0.0e+00	547	COG0281	Malic enzyme	432
2918239884	818	95.97	1	813	2	764	0.0e+00	988.9	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
2918239886	179	76.92	1	171	6	165	2.3e-17	57.6	COG3166	Tfp pilus assembly protein PilN	206
2918239887	339	48.82	184	307	87	169	1.9e-13	44.7	COG3168	Tfp pilus assembly protein PilP	170
2918239888	424	60.42	19	417	284	715	7.0e-125	411.9	COG4796	Type II secretory pathway, component HofQ	709
2918239889	163	91.86	1	162	11	168	7.3e-55	180	COG0703	Shikimate kinase	172
2918239890	365	98.89	1	360	1	356	0.0e+00	469.6	COG0337	3-dehydroquinate synthetase	360
2918239891	538	97.45	1	256	1	267	5.9e-58	190.5	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
2918239892	1481	95.07	1178	1480	3	291	1.7e-96	317.3	COG0070	Glutamate synthase domain 3	301
2918239892	1481	99.18	692	1173	2	486	0.0e+00	659.6	COG0069	Glutamate synthase domain 2	485
2918239892	1481	99.73	3	380	2	372	0.0e+00	459.1	COG0067	Glutamate synthase domain 1	371
2918239893	472	98.47	26	472	2	452	0.0e+00	559.9	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2918239894	354	99.15	1	352	3	352	0.0e+00	482.2	COG0407	Uroporphyrinogen-III decarboxylase	352
2918239895	115	74.22	5	115	33	127	2.3e-28	93.4	COG3111	Predicted periplasmic protein YdeI with OB-fold, BOF family	128
2918239896	414	96.46	23	414	12	392	1.1e-41	137.1	COG2814	Predicted arabinose efflux permease, MFS family	394
2918239897	297	97.67	1	297	1	294	2.8e-66	218.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918239898	408	99.52	1	408	2	413	6.4e-125	411.6	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918239899	242	97.39	1	241	6	266	2.7e-67	221.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918239900	156	85.09	2	151	12	148	4.8e-41	134.6	COG4706	Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain	161
2918239901	393	98.07	2	393	8	413	2.6e-78	257.9	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918239903	775	97.72	5	774	16	785	1.4e-108	358.4	COG4258	Predicted exporter	788
2918239905	141	87.05	6	140	9	129	6.4e-26	85.4	COG0824	Acyl-CoA thioesterase FadM	137
2918239906	511	97.59	2	507	3	488	0.0e+00	489.4	COG2986	Histidine ammonia-lyase	498
2918239907	307	96.44	5	307	3	300	3.9e-94	309.6	COG4261	Predicted acyltransferase, LPLAT superfamily	309
2918239908	244	46.52	1	242	7	173	9.8e-12	40.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918239909	557	9.6	17	93	43	95	7.2e-38	4.5	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918239909	557	60.81	447	556	38	127	7.9e-15	48.8	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2918239909	557	68.48	88	449	166	543	7.2e-38	113.8	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918239910	181	88.06	2	181	14	190	1.2e-51	169.8	COG4648	Uncharacterized membrane protein	201
2918239911	84	95.06	2	81	3	79	4.1e-18	59.8	COG0236	Acyl carrier protein	80
2918239912	90	96.3	3	89	3	80	1.5e-19	64.4	COG0236	Acyl carrier protein	80
2918239913	265	77.01	23	262	5	205	2.1e-28	93.7	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918239915	260	94.32	1	256	5	253	4.0e-53	175.3	COG1192	Cellulose biosynthesis protein BcsQ	259
2918239916	102	97.96	1	99	1	96	7.5e-29	94.7	COG4680	mRNA-degrading endonuclease (mRNA interferase) HigB, toxic component of the HigAB toxin-antitoxin module	98
2918239917	118	95.83	1	116	4	118	1.2e-30	101	COG5499	Antitoxin component HigA of the HigAB toxin-antitoxin module, contains an N-terminal HTH domain	120
2918239918	144	78	4	142	28	144	4.8e-18	59.7	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2918239919	486	98.99	2	486	6	497	0.0e+00	624	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
2918239920	1105	38.14	48	210	17	98	5.5e+00	5.7	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
2918239920	1105	99.06	205	1103	2	845	0.0e+00	865.2	COG3264	Small-conductance mechanosensitive channel	835
2918239921	580	99.13	2	574	2	570	0.0e+00	834.2	COG3263	NhaP-type Na+/H+ and K+/H+ antiporter with C-terminal TrkAC and CorC domains	574
2918239922	565	98.42	1	546	4	562	0.0e+00	522.7	COG2303	Choline dehydrogenase or related flavoprotein	542
2918239923	490	98.96	7	485	2	475	0.0e+00	597.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918239924	221	91.87	1	198	12	203	1.1e-16	56.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918239925	667	98.52	8	565	8	538	0.0e+00	646.9	COG1292	Choline-glycine betaine transporter	537
2918239927	254	87.84	5	244	28	251	9.5e-78	254.8	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
2918239928	442	92.16	10	425	20	395	0.0e+00	436.4	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
2918239929	430	94.37	1	430	24	425	4.4e-121	399	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
2918239930	511	99.21	3	510	3	507	0.0e+00	755.1	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
2918239931	137	92.11	33	137	8	112	1.4e-25	83.7	COG0607	Rhodanese-related sulfurtransferase	110
2918239932	83	100	1	78	1	80	4.9e-23	75.6	COG0695	Glutaredoxin	80
2918239933	163	92.99	5	162	5	150	3.8e-62	202.7	COG1952	Preprotein translocase subunit SecB	157
2918239934	151	97.4	1	151	1	150	2.1e-66	216.9	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
2918239937	478	98.5	1	472	2	461	0.0e+00	618.4	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918239938	360	96.97	1	360	5	356	0.0e+00	462.4	COG3852	Signal transduction histidine kinase, nitrogen specific	363
2918239939	177	76.24	21	105	23	99	5.9e-18	56.7	COG1605	Chorismate mutase	101
2918239940	468	98.43	2	468	7	445	0.0e+00	573.6	COG0174	Glutamine synthetase	443
2918239941	484	71.93	393	483	15	96	1.1e-07	25	COG0607	Rhodanese-related sulfurtransferase	110
2918239941	484	98.96	1	386	2	381	1.8e-123	406.5	COG0301	Adenylyl- and sulfurtransferase ThiI, participates in tRNA 4-thiouridine and thiamine biosynthesis	383
2918239942	606	99.67	1	604	2	602	0.0e+00	998.7	COG1217	Predicted membrane GTPase involved in stress response	603
2918239945	455	85.32	46	320	47	325	1.2e-68	225.6	COG3344	Retron-type reverse transcriptase	328
2918239946	134	66.2	13	130	3	96	8.5e-14	46.1	COG0727	Fe-S-cluster containining protein	132
2918239947	816	99.07	2	816	6	750	0.0e+00	910.1	COG0058	Glucan phosphorylase	750
2918239948	336	99.09	3	336	2	326	0.0e+00	460.7	COG0158	Fructose-1,6-bisphosphatase	326
2918239949	198	96.15	1	198	6	180	2.8e-57	187.9	COG3803	Uncharacterized conserved protein, DUF924 family	182
2918239950	193	38.59	27	193	262	425	1.9e-56	186.4	COG0840	Methyl-accepting chemotaxis protein	408
2918239952	190	96	1	184	4	171	1.5e-56	184.8	COG3040	Bacterial lipocalin	174
2918239953	454	95.75	1	450	12	417	9.7e-96	315.1	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918239954	248	97.91	10	246	4	237	4.7e-73	239.8	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918239955	190	88.14	1	181	1	171	1.7e-48	159.4	COG3758	Various environmental stresses-induced protein Ves (function unknown)	193
2918239956	557	98.22	2	557	6	556	0.0e+00	1011.3	COG2987	Urocanate hydratase	561
2918239957	510	99.4	1	500	2	496	0.0e+00	709.3	COG2986	Histidine ammonia-lyase	498
2918239958	468	96.97	1	460	5	452	0.0e+00	599.6	COG1113	L-asparagine transporter and related permeases	462
2918239959	401	95.82	1	401	12	401	0.0e+00	432.1	COG1228	Imidazolonepropionase or related amidohydrolase	406
2918239960	267	97.43	1	266	6	270	2.0e-103	339.7	COG3741	N-formylglutamate amidohydrolase	272
2918239961	323	90.85	5	318	12	279	1.9e-49	163	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918239962	145	99.31	1	145	1	144	6.0e-59	192.9	COG1490	D-Tyr-tRNAtyr deacylase	145
2918239963	548	2.99	527	548	515	530	0.0e+00	3.3	COG3131	Periplasmic glucans biosynthesis protein	534
2918239963	548	89.35	1	501	37	514	0.0e+00	728.5	COG3131	Periplasmic glucans biosynthesis protein	534
2918239964	857	98.91	61	832	7	734	0.0e+00	1193.4	COG2943	Membrane glycosyltransferase	736
2918239965	266	95.76	1	266	8	278	1.9e-58	192.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918239966	320	90.79	96	320	20	226	7.4e-81	264.9	COG0765	ABC-type amino acid transport system, permease component	222
2918239967	247	99.17	3	247	2	241	2.8e-108	354.9	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918239968	647	91.53	182	647	36	424	3.8e-114	376.7	COG0840	Methyl-accepting chemotaxis protein	408
2918239969	638	91.76	185	638	36	425	7.8e-115	379	COG0840	Methyl-accepting chemotaxis protein	408
2918239970	235	94.31	1	235	9	240	1.0e-47	156.8	COG1385	16S rRNA U1498 N3-methylase RsmE	246
2918239971	263	95.75	3	257	3	250	6.0e-91	298.7	COG0805	Sec-independent protein secretion pathway component TatC	255
2918239972	126	73.4	1	93	1	69	3.4e-20	66.6	COG1826	Sec-independent protein translocase protein TatA	94
2918239973	94	97.87	1	93	1	92	5.6e-21	69.2	COG1826	Sec-independent protein translocase protein TatA	94
2918239974	111	97.92	5	107	1	94	8.7e-32	103.6	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
2918239975	130	94.64	1	108	5	110	1.5e-44	144.7	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
2918239976	536	94.53	1	515	3	486	0.0e+00	574.3	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
2918239977	207	95.59	3	202	7	201	2.4e-55	181.4	COG3165	Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain	204
2918239978	256	100	18	256	1	239	2.6e-99	325.4	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918239981	139	84.26	15	138	7	97	5.8e-06	19.8	COG3937	Polyhydroxyalkanoate synthesis regulator phasin	108
2918239982	258	87.96	18	135	9	103	6.4e-13	37.9	COG3937	Polyhydroxyalkanoate synthesis regulator phasin	108
2918239983	204	81.34	1	202	13	182	7.7e-24	79.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918239984	560	99.78	107	559	1	451	0.0e+00	528.4	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
2918239985	283	94.58	7	269	15	293	1.0e-36	121.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918239986	559	99.78	107	558	1	451	0.0e+00	554.9	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
2918239987	125	96.67	1	118	3	118	6.1e-45	146.4	COG3536	Uncharacterized conserved protein, DUF971 family	120
2918239988	448	99.55	1	448	3	444	0.0e+00	719.8	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
2918239989	176	95.51	1	175	5	174	1.3e-86	283	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
2918239990	423	97.22	1	423	4	422	1.9e-122	403.5	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2918239991	334	98.73	12	324	4	314	2.0e-112	369.5	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
2918239992	172	85.47	1	168	12	164	2.2e-48	158.4	COG2065	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	179
2918239993	143	95.74	5	143	4	138	3.7e-44	144.4	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
2918239994	189	95.36	1	189	10	194	6.5e-66	215.8	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
2918239995	299	86.86	7	293	36	273	7.5e-41	135.1	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2918239996	317	99.37	3	317	2	314	3.3e-96	316.2	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2918239997	133	53.02	5	133	2	124	4.5e-31	102.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918239998	121	50.43	2	121	2	118	1.0e-30	101.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918239999	184	81.82	24	178	7	141	1.8e-29	96.6	COG0835	Chemotaxis signal transduction protein	165
2918240000	686	81.41	300	679	79	424	2.7e-88	291.5	COG0840	Methyl-accepting chemotaxis protein	408
2918240001	1634	11.54	12	177	19	105	0.0e+00	2.8	COG0643	Chemotaxis protein histidine kinase CheA	716
2918240001	1634	11.94	429	566	3	92	0.0e+00	49.6	COG0643	Chemotaxis protein histidine kinase CheA	716
2918240001	1634	12.73	565	703	6	101	0.0e+00	43	COG0643	Chemotaxis protein histidine kinase CheA	716
2918240001	1634	14.06	863	999	6	111	0.0e+00	56.1	COG0643	Chemotaxis protein histidine kinase CheA	716
2918240001	1634	16.05	705	866	6	126	0.0e+00	27.6	COG0643	Chemotaxis protein histidine kinase CheA	716
2918240001	1634	54.77	984	1503	336	748	0.0e+00	541.8	COG0643	Chemotaxis protein histidine kinase CheA	716
2918240002	157	60	1	140	14	112	3.2e-06	21.2	COG0835	Chemotaxis signal transduction protein	165
2918240003	205	89.32	1	205	23	231	2.8e-69	227.2	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
2918240005	239	100	1	238	1	246	8.7e-79	258.5	COG1385	16S rRNA U1498 N3-methylase RsmE	246
2918240006	468	98.66	3	451	3	443	0.0e+00	580.4	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918240007	622	98.02	21	459	8	452	7.4e-106	348.9	COG1231	Monoamine oxidase	450
2918240008	183	98.9	3	183	2	180	9.3e-64	208.7	COG3038	Cytochrome b561	181
2918240009	192	99.48	2	192	2	193	4.9e-63	206.5	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
2918240010	633	88.27	1	583	29	487	0.0e+00	520.9	COG0513	Superfamily II DNA and RNA helicase	513
2918240011	262	91.52	1	251	14	272	3.7e-22	73.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918240012	281	95.22	1	281	13	291	4.3e-96	315.8	COG0685	5,10-methylenetetrahydrofolate reductase	291
2918240013	469	99.52	9	461	3	419	0.0e+00	594.5	COG0499	S-adenosylhomocysteine hydrolase	420
2918240015	133	67.52	1	131	15	120	1.4e-31	103.6	COG1607	Acyl-CoA hydrolase	157
2918240016	411	93.35	10	411	3	409	3.2e-85	280.5	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
2918240017	277	90.7	1	277	22	294	3.0e-17	57.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918240018	128	99.2	1	128	1	124	8.1e-44	142.9	COG3686	Uncharacterized conserved protein, MAPEG superfamily	125
2918240019	383	96.31	3	378	11	375	1.6e-115	380.3	COG2821	Membrane-bound lytic murein transglycosylase	373
2918240020	151	95.92	2	151	4	144	8.5e-33	108	COG3909	Cytochrome c556	147
2918240021	132	21.03	11	132	104	185	1.7e-03	11.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918240022	131	13.92	35	131	36	95	4.3e-02	5.3	COG0172	Seryl-tRNA synthetase	429
2918240023	557	85.46	26	555	5	580	3.1e-94	310.6	COG0272	NAD-dependent DNA ligase	667
2918240024	396	99.49	1	396	1	387	0.0e+00	624.5	COG0192	S-adenosylmethionine synthetase	388
2918240025	331	65.27	117	289	19	174	1.6e-17	57.4	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918240025	331	67.8	7	123	11	90	3.2e-14	46.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918240026	665	99.1	1	664	6	662	0.0e+00	1013.8	COG0021	Transketolase	663
2918240027	353	97.61	6	346	2	328	1.9e-118	389.9	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
2918240028	387	98.74	1	386	5	397	0.0e+00	499.2	COG0126	3-phosphoglycerate kinase	395
2918240030	109	79.65	1	108	12	101	6.7e-09	29.7	COG3895	Membrane-bound inhibitor of C-type lysozyme	112
2918240031	354	100	1	329	1	288	1.0e-107	354	COG0191	Fructose/tagatose bisphosphate aldolase	286
2918240032	706	64.1	213	702	217	641	1.7e-101	334.4	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918240032	706	93.23	12	149	8	131	3.8e-32	104.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918240033	166	73.13	1	163	55	220	2.3e-36	119.9	COG1451	Predicted metal-dependent hydrolase	223
2918240034	98	97.89	1	98	2	94	4.3e-40	130.1	COG4519	Uncharacterized protein	95
2918240035	730	98.4	9	725	2	676	0.0e+00	589.8	COG1289	Uncharacterized membrane protein YccC	674
2918240036	393	98.28	1	393	3	402	0.0e+00	509	COG2081	Predicted flavoprotein YhiN	408
2918240037	461	72.31	1	391	28	403	0.0e+00	439.6	COG0513	Superfamily II DNA and RNA helicase	513
2918240038	475	50.39	261	470	2	194	1.6e-37	5.3	COG0477	MFS family permease	338
2918240038	475	77.28	11	299	3	298	1.6e-37	121.3	COG0477	MFS family permease	338
2918240039	443	98.9	2	443	3	453	4.3e-49	161.7	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2918240040	480	97.37	5	478	12	455	5.4e-86	283.4	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2918240041	600	97.49	16	462	7	395	1.6e-94	311.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918240047	1317	100	101	523	1	403	0.0e+00	563	COG0506	Proline dehydrogenase	391
2918240047	1317	100	526	1317	1	773	0.0e+00	1207.6	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
2918240048	497	97	1	493	3	487	0.0e+00	532.9	COG0591	Na+/proline symporter	493
2918240049	278	99.64	1	278	1	278	4.2e-112	368	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
2918240050	585	99.64	3	577	2	554	0.0e+00	643.1	COG2192	Predicted carbamoyl transferase, NodU family	555
2918240051	376	69.19	26	368	112	394	8.5e-38	125.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918240052	298	39.66	84	297	191	351	1.1e-06	15.9	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
2918240053	475	84.96	173	464	11	219	6.9e-15	48.7	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
2918240054	320	59.9	6	318	159	403	2.2e-07	25.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918240057	212	39.51	36	195	56	136	7.0e-06	19.6	COG3642	tRNA A-37 threonylcarbamoyl transferase component Bud32	204
2918240058	600	99.16	12	592	2	588	0.0e+00	566.8	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918240059	469	98.52	1	469	6	470	0.0e+00	660.7	COG2870	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase	467
2918240061	270	11.88	220	267	259	296	2.7e-54	14	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918240061	270	66.25	8	222	3	214	2.7e-54	163.1	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918240062	391	73.56	1	388	12	406	9.3e-41	134	COG0578	Glycerol-3-phosphate dehydrogenase	532
2918240063	110	98.11	1	106	2	105	8.3e-32	104.2	COG2076	Multidrug transporter EmrE and related cation transporters	106
2918240064	296	98.01	5	296	2	296	2.7e-57	189.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918240065	423	99.28	2	422	2	416	0.0e+00	501.4	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
2918240066	715	98.87	5	711	8	710	0.0e+00	867.4	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918240067	468	97.44	34	459	9	388	2.3e-34	113.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918240069	1821	64.97	1269	1421	27	141	8.6e-15	48.6	COG4935	Regulatory P domain of the subtilisin-like proprotein convertases and other proteases	177
2918240070	478	91.3	5	450	35	454	1.5e-86	285.2	COG1538	Outer membrane protein TolC	457
2918240072	628	99.54	137	595	2	433	0.0e+00	738.8	COG0422	Thiamine biosynthesis protein ThiC	432
2918240073	427	86.61	1	419	13	400	9.1e-64	209.8	COG1457	Purine-cytosine permease or related protein	442
2918240075	205	87.21	42	198	12	161	6.4e-22	72.4	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918240076	148	96.6	1	148	3	144	4.1e-56	183.3	COG3151	Uncharacterized protein YqiB, DUF1249 family	147
2918240077	269	91.39	11	269	2	362	1.2e-32	107.9	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2918240078	202	97.94	1	192	3	192	3.6e-67	220.4	COG3150	Predicted esterase YcpF, UPF0227 family	191
2918240079	634	98.6	4	633	4	635	0.0e+00	750.9	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
2918240081	172	80	1	170	43	214	1.1e-46	153.6	COG3577	Predicted aspartyl protease	215
2918240082	752	92	4	751	7	754	0.0e+00	823.4	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
2918240083	236	97.37	1	193	5	189	5.8e-42	137.7	COG3009	Uncharacterized lipoprotein YmbA	190
2918240084	486	95.83	10	214	1	207	1.3e-45	149.2	COG3726	Uncharacterized membrane protein affecting hemolysin expression	214
2918240085	404	46.67	112	192	48	89	6.1e-27	8.1	COG3830	ACT domain, binds amino acids and other small ligands	90
2918240085	404	93.33	2	93	2	85	6.1e-27	76.7	COG3830	ACT domain, binds amino acids and other small ligands	90
2918240085	404	99.06	186	396	2	211	1.5e-76	250.5	COG0560	Phosphoserine phosphatase	212
2918240086	287	98.84	8	281	3	257	2.5e-83	273.2	COG0688	Phosphatidylserine decarboxylase	239
2918240087	269	95.12	3	269	11	283	1.7e-72	238.2	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2918240089	283	98.13	1	283	3	264	2.5e-84	276.6	COG1291	Flagellar motor component MotA	266
2918240090	341	97.78	7	274	7	270	2.2e-69	228.4	COG1360	Flagellar motor protein MotB	244
2918240091	343	92.72	35	343	17	296	1.5e-96	317.3	COG1162	Putative ribosome biogenesis GTPase RsgA	301
2918240092	180	96.74	1	180	3	180	6.1e-91	297.2	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
2918240093	203	96.65	1	203	6	207	3.2e-79	259.7	COG2860	Uncharacterized membrane protein YeiH	209
2918240094	357	99.71	10	350	2	341	0.0e+00	457	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
2918240095	286	94.44	6	281	16	287	3.9e-82	270	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
2918240096	157	97.32	4	151	2	146	6.6e-49	159.8	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
2918240097	477	95.86	26	404	11	265	2.5e-78	257.3	COG0860	N-acetylmuramoyl-L-alanine amidase	231
2918240098	632	99.53	1	631	3	644	0.0e+00	691.6	COG0323	DNA mismatch repair ATPase MutL	638
2918240099	313	92.53	1	308	9	293	1.2e-113	373.4	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
2918240100	75	81.82	1	65	12	74	1.1e-32	105.9	COG1923	sRNA-binding regulator protein Hfq	77
2918240101	433	96.84	8	420	3	401	0.0e+00	512.9	COG2262	50S ribosomal subunit-associated GTPase HflX	411
2918240102	394	96.68	67	356	7	297	6.8e-75	246.2	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918240103	289	97.67	1	288	4	297	2.4e-77	254.6	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918240104	395	98.47	5	393	2	386	1.7e-114	376.8	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
2918240105	430	99.53	2	430	2	429	0.0e+00	644.6	COG0104	Adenylosuccinate synthase	430
2918240107	644	87.06	159	644	55	424	9.5e-78	256.8	COG0840	Methyl-accepting chemotaxis protein	408
2918240108	521	97.43	13	520	5	534	0.0e+00	444.1	COG1178	ABC-type Fe3+ transport system, permease component	540
2918240109	337	99.67	48	337	1	300	4.2e-58	191.4	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918240111	392	94.95	1	389	15	390	4.9e-17	56.1	COG2807	Cyanate permease	395
2918240112	401	96.49	5	384	11	395	3.9e-72	237.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918240113	549	97.01	18	547	9	559	2.1e-83	274.7	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918240114	602	50.12	74	294	145	345	5.4e-54	25.3	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918240114	602	50.87	282	578	6	209	5.4e-54	156.1	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918240115	90	98.81	2	90	2	84	5.7e-18	59.9	COG1977	Molybdopterin converting factor, small subunit	84
2918240116	136	85.93	3	134	4	119	2.5e-23	76.9	COG1310	Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif	134
2918240117	390	86.84	285	390	12	110	1.4e-21	70.2	COG0607	Rhodanese-related sulfurtransferase	110
2918240117	390	95.02	11	263	2	249	7.9e-86	281.1	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
2918240118	839	97.15	1	338	10	350	1.9e-113	373	COG5322	Predicted amino acid dehydrogenase	351
2918240118	839	97.78	377	839	7	402	0.0e+00	470.3	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2918240120	426	29.62	7	197	273	389	3.7e-08	15	COG2814	Predicted arabinose efflux permease, MFS family	394
2918240120	426	45.82	191	404	204	384	3.7e-08	18.6	COG2814	Predicted arabinose efflux permease, MFS family	394
2918240121	347	55.2	105	342	42	195	1.8e-11	38.8	COG0500	SAM-dependent methyltransferase	257
2918240122	320	81.82	188	318	14	121	9.5e-22	70.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918240124	1039	91.45	98	1039	69	795	6.8e-36	116.6	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918240126	497	43.48	16	496	64	223	2.3e-06	21.9	COG0457	Tetratricopeptide (TPR) repeat	291
2918240129	868	99.44	19	748	2	708	0.0e+00	850.7	COG0557	Exoribonuclease R	706
2918240130	248	91.25	1	247	22	261	1.5e-85	281.1	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2918240131	141	99.11	2	112	1	111	1.2e-40	132.2	COG0360	Ribosomal protein S6	112
2918240132	76	84.81	1	68	13	79	8.1e-32	104.1	COG0238	Ribosomal protein S18	75
2918240134	148	98.65	1	148	1	146	1.9e-54	178.2	COG0359	Ribosomal protein L9	148
2918240135	465	99.54	18	456	2	435	0.0e+00	572.1	COG0305	Replicative DNA helicase	435
2918240136	539	75.11	1	536	156	689	3.7e-53	175	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918240137	765	99.6	43	671	1	496	0.0e+00	606.5	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
2918240138	195	92.68	1	191	16	205	1.5e-62	205.1	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2918240140	149	97.35	1	149	3	149	1.6e-57	188.3	COG3241	Azurin	151
2918240141	275	93.07	21	275	5	259	5.3e-76	249.7	COG0171	NH3-dependent NAD+ synthetase	268
2918240142	401	91.95	1	401	4	380	2.4e-113	373.2	COG1488	Nicotinic acid phosphoribosyltransferase	405
2918240143	378	96.45	6	377	8	360	1.3e-88	291.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918240144	304	97.67	1	303	4	297	3.2e-94	310.2	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918240145	429	95.05	95	421	10	316	3.5e-96	316.7	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918240146	291	99.61	2	285	2	254	5.0e-110	360.8	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918240147	238	99.16	3	237	2	236	6.6e-101	330.7	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918240148	254	97.56	1	244	7	246	3.2e-96	316.1	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2918240149	369	94.85	8	368	5	372	4.9e-55	181	COG2942	Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family	388
2918240150	210	52.63	1	203	11	120	1.3e-19	66	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918240151	106	9.94	1	99	15	93	2.3e-02	7.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918240152	685	99.85	1	668	1	676	0.0e+00	675.2	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2918240153	176	86.62	26	176	4	139	4.2e-43	141.2	COG2193	Bacterioferritin (cytochrome b1)	157
2918240154	113	48.67	1	111	10	82	3.9e-05	17.7	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
2918240155	296	83.05	2	293	59	347	8.3e-39	125.8	COG1075	Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold	336
2918240156	297	95.35	1	291	10	296	4.9e-45	148.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918240157	261	76.52	121	261	25	125	7.9e-26	84.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918240159	335	91.11	2	334	16	343	3.5e-19	63	COG0628	Predicted PurR-regulated permease PerM	355
2918240160	423	19.8	294	422	255	374	1.6e-69	47.9	COG0443	Molecular chaperone DnaK (HSP70)	579
2918240160	423	53.8	1	319	6	331	1.6e-69	187.4	COG0443	Molecular chaperone DnaK (HSP70)	579
2918240161	321	37.66	1	164	4	148	5.6e-81	137.6	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2918240161	321	38.44	159	319	212	359	5.6e-81	127.7	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2918240163	237	94.19	7	237	5	231	2.7e-60	198.1	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918240164	449	13.11	374	438	154	212	3.4e-24	9.2	COG2271	Sugar phosphate permease	448
2918240164	449	74.89	7	358	24	360	3.4e-24	74.2	COG2271	Sugar phosphate permease	448
2918240165	458	98.66	21	428	4	371	9.9e-89	292	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918240166	293	98.01	1	293	1	295	4.6e-60	198.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918240167	315	97.86	6	315	6	325	1.3e-84	278.2	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918240168	446	93.56	2	446	20	440	2.4e-39	129.7	COG2271	Sugar phosphate permease	448
2918240170	443	93.07	1	440	22	451	0.0e+00	477.8	COG1113	L-asparagine transporter and related permeases	462
2918240175	207	28.5	14	175	40	157	1.7e-03	11.6	COG1419	Flagellar biosynthesis GTPase FlhF	407
2918240185	399	94.62	36	398	5	338	8.1e-52	170	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
2918240203	235	73.87	22	208	51	197	1.4e-19	65.2	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918240206	249	33.74	119	234	10	91	1.5e-08	6.9	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
2918240206	249	34.16	21	119	62	144	1.5e-08	25.9	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
2918240218	183	50.62	29	160	72	153	5.0e-08	27.9	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918240219	102	89.47	5	100	6	90	5.6e-18	58.7	COG4453	Uncharacterized conserved protein, DUF1778 family	95
2918240225	936	93.77	530	933	5	380	5.7e-61	200.3	COG0247	Fe-S oxidoreductase	388
2918240225	936	99.15	10	519	3	467	5.7e-94	309.6	COG0277	FAD/FMN-containing dehydrogenase	459
2918240226	381	96.95	6	380	2	351	0.0e+00	449.5	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2918240227	556	99.62	13	552	2	526	0.0e+00	718.7	COG1620	L-lactate permease	522
2918240228	255	98.76	1	246	2	239	2.2e-66	218	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918240229	160	96.08	4	158	5	151	1.3e-62	204.2	COG0691	tmRNA-binding protein	153
2918240230	144	96.58	2	144	2	142	1.9e-53	174.3	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
2918240231	121	33.33	1	104	63	112	2.7e-10	34.6	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
2918240232	111	71.72	2	111	33	136	3.7e-34	111.9	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2918240233	557	99.28	1	556	1	554	0.0e+00	642	COG0497	DNA repair ATPase RecN	557
2918240234	184	83.16	1	173	33	195	1.2e-59	195.8	COG0576	Molecular chaperone GrpE (heat shock protein)	193
2918240235	642	99.01	1	605	6	605	0.0e+00	839.7	COG0443	Molecular chaperone DnaK (HSP70)	579
2918240236	374	99.48	1	373	1	383	0.0e+00	492.9	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2918240237	268	99.25	1	267	3	267	2.8e-109	359	COG0289	Dihydrodipicolinate reductase	266
2918240239	378	98.92	2	378	2	368	0.0e+00	531.7	COG0505	Carbamoylphosphate synthase small subunit	368
2918240240	1073	94.39	564	948	1	387	0.0e+00	286.5	COG0458	Carbamoylphosphate synthase large subunit	400
2918240240	1073	97.8	13	427	1	401	0.0e+00	731.5	COG0458	Carbamoylphosphate synthase large subunit	400
2918240241	160	98.68	8	160	1	150	4.1e-54	177	COG0782	Transcription elongation factor, GreA/GreB family	151
2918240243	102	93.81	2	99	2	92	3.5e-29	95	COG1534	RNA-binding protein YhbY	97
2918240244	208	99.02	5	208	1	203	1.0e-81	267.9	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
2918240245	636	99.5	6	604	1	598	0.0e+00	901.9	COG0465	ATP-dependent Zn proteases	596
2918240246	283	96.04	14	283	4	270	5.1e-98	322	COG0294	Dihydropteroate synthase	274
2918240247	446	97.49	1	446	10	475	0.0e+00	446.5	COG1109	Phosphomannomutase	464
2918240248	251	98.41	1	251	1	248	5.0e-88	289.1	COG0149	Triosephosphate isomerase	251
2918240249	130	87.1	1	104	1	81	2.0e-29	95.5	COG1314	Preprotein translocase subunit SecG	86
2918240252	169	96.75	16	168	5	153	6.5e-56	182.7	COG0779	Ribosome maturation factor RimP	153
2918240253	493	96.48	159	373	2	193	8.7e-79	258.1	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
2918240254	843	99.29	341	843	3	559	0.0e+00	544.6	COG0532	Translation initiation factor IF-2, a GTPase	509
2918240255	133	99.16	1	121	1	118	1.4e-39	129	COG0858	Ribosome-binding factor A	118
2918240256	305	97.74	2	304	6	308	1.3e-105	347.6	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
2918240258	89	100	1	89	1	89	4.4e-35	113.9	COG0184	Ribosomal protein S15P/S13E	89
2918240259	701	99.28	1	695	4	692	0.0e+00	1025.1	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
2918240260	116	47.72	2	114	97	190	5.3e-20	66.6	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918240262	289	96.33	3	289	2	290	1.9e-93	307.4	COG3662	Uncharacterized conserved protein, DUF2236 family	300
2918240263	644	100	66	627	1	552	0.0e+00	804.8	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918240264	554	99.34	45	542	4	453	0.0e+00	580.7	COG0166	Glucose-6-phosphate isomerase	446
2918240265	287	99.3	1	283	1	283	2.8e-119	391.7	COG0414	Panthothenate synthetase	285
2918240266	266	97.76	3	266	3	264	3.8e-109	358.4	COG0413	Ketopantoate hydroxymethyltransferase	268
2918240267	159	93.17	2	159	3	152	3.0e-52	170.8	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
2918240268	462	95.18	33	447	5	399	3.2e-118	389.7	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
2918240270	482	98.72	1	480	5	465	0.0e+00	553.8	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918240271	989	74.11	615	980	99	390	9.9e-58	191	COG0642	Signal transduction histidine kinase	336
2918240271	989	96.2	1	523	8	488	6.5e-72	236.8	COG0591	Na+/proline symporter	493
2918240273	295	55.42	1	275	9	274	1.8e-84	278.8	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2918240274	148	94.17	28	147	6	118	2.6e-39	128.6	COG1734	RNA polymerase-binding transcription factor DksA	120
2918240275	390	98.23	7	388	5	393	3.3e-106	349.8	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918240276	237	97.45	1	237	1	229	2.5e-82	270.2	COG1489	DNA-binding protein, stimulates sugar fermentation	235
2918240277	105	91.59	1	105	7	104	9.4e-22	71.3	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2918240278	293	93.33	1	288	20	299	1.8e-89	293.8	COG4558	ABC-type hemin transport system, periplasmic component	300
2918240279	345	97.91	2	345	5	332	8.0e-95	312	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918240280	255	99.23	1	255	1	257	3.5e-100	328.7	COG4559	ABC-type hemin transport system, ATPase component	259
2918240281	297	99.32	1	297	1	293	2.2e-76	251.3	COG3016	Uncharacterized iron-regulated protein	295
2918240283	92	71.07	1	92	29	114	5.9e-08	26.9	COG3070	Transcriptional regulator of competence genes, TfoX/Sxy family	121
2918240284	520	98.81	2	336	3	335	0.0e+00	431	COG2187	Aminoglycoside phosphotransferase family enzyme	337
2918240284	520	98.82	336	514	1	168	5.4e-52	169.9	COG0645	Predicted kinase	170
2918240285	773	81.21	134	766	70	648	0.0e+00	610.5	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2918240287	110	91.74	2	110	7	106	5.8e-30	98.2	COG3098	Uncharacterized conserved protein YqcC, DUF446 family	109
2918240289	574	99.46	3	570	3	554	0.0e+00	740.6	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918240290	163	97.53	1	161	3	160	3.0e-65	213.3	COG0440	Acetolactate synthase, small subunit	163
2918240291	338	99.11	1	336	3	337	0.0e+00	515.7	COG0059	Ketol-acid reductoisomerase	338
2918240292	283	96.62	33	282	2	230	2.6e-71	234.3	COG1183	Phosphatidylserine synthase	234
2918240293	337	96.19	22	311	4	281	4.3e-90	296	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2918240294	203	91.51	1	197	7	200	6.8e-58	190.1	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
2918240303	1159	99.17	9	1152	2	1071	0.0e+00	1131.9	COG1330	Exonuclease V gamma subunit	1078
2918240304	1225	99.05	5	1181	12	1152	0.0e+00	889.6	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2918240305	694	90.64	19	691	60	727	1.1e-130	431.3	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
2918240306	316	97.67	11	302	2	295	3.6e-54	178.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918240307	508	99.16	15	493	2	476	0.0e+00	504.1	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918240308	295	99.65	1	292	1	285	6.2e-103	338.2	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918240309	114	98.28	1	114	1	114	1.3e-39	129	COG3450	Predicted enzyme of the cupin superfamily	116
2918240310	310	99.01	3	310	3	302	0.0e+00	442.6	COG4589	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase	303
2918240311	207	62.45	29	206	67	229	3.1e-24	79.8	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918240313	441	31.47	130	199	137	209	2.6e-04	13.2	COG0671	Membrane-associated phospholipid phosphatase	232
2918240313	441	35.78	62	154	3	85	2.6e-04	15.7	COG0671	Membrane-associated phospholipid phosphatase	232
2918240314	584	95.78	1	281	7	301	3.7e-67	220.3	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918240315	201	94.33	15	201	3	185	5.8e-26	86.1	COG0558	Phosphatidylglycerophosphate synthase	192
2918240316	254	96.91	10	254	3	253	8.4e-24	78.6	COG0730	Uncharacterized membrane protein YfcA	258
2918240317	104	89.9	3	98	4	92	1.9e-27	89.3	COG1359	Quinol monooxygenase YgiN	100
2918240318	195	99.48	2	193	1	190	1.2e-53	176.1	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
2918240319	298	97.34	4	297	4	296	8.4e-73	239.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918240320	555	96.88	8	554	14	541	0.0e+00	647.2	COG0405	Gamma-glutamyltranspeptidase	539
2918240321	639	84.94	226	639	65	425	2.0e-113	374.4	COG0840	Methyl-accepting chemotaxis protein	408
2918240322	294	98.99	1	294	1	293	5.8e-121	397.6	COG2321	Predicted metalloprotease	295
2918240323	239	98.25	3	239	5	228	1.2e-79	261.4	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2918240324	201	88.6	2	201	26	227	2.2e-59	194.9	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2918240325	361	80.96	2	354	84	436	1.3e-85	282.2	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
2918240326	431	98.19	1	430	5	439	0.0e+00	583.3	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
2918240327	159	60.32	5	152	48	161	6.0e-12	40	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918240328	417	46.74	213	408	12	190	5.7e-19	19.5	COG0477	MFS family permease	338
2918240328	417	72.32	12	279	2	278	5.7e-19	49.2	COG0477	MFS family permease	338
2918240329	480	96.71	3	453	2	442	0.0e+00	566.5	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
2918240330	335	98.26	1	335	6	344	1.4e-116	384	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
2918240332	374	97.68	68	374	7	301	4.3e-81	266.5	COG2813	16S rRNA G1207 methylase RsmC	300
2918240333	234	90	154	234	8	79	7.9e-22	70.6	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918240334	258	98.88	4	258	3	267	3.4e-54	178.4	COG1018	Ferredoxin-NADP reductase	266
2918240335	139	100	1	133	1	131	5.6e-51	166.7	COG1970	Large-conductance mechanosensitive channel	130
2918240336	455	99.56	1	455	1	454	0.0e+00	657	COG1066	Predicted ATP-dependent serine protease	456
2918240337	505	97.37	1	451	5	448	0.0e+00	495.2	COG2233	Xanthine/uracil permease	451
2918240339	688	99.18	35	688	1	606	0.0e+00	882.2	COG1966	Carbon starvation protein CstA	575
2918240340	65	100	1	65	1	65	8.0e-38	122.7	COG2879	Uncharacterized short protein YbdD, DUF466 family	65
2918240341	325	98.77	5	324	1	322	3.8e-98	323.1	COG0523	GTPase, G3E family	323
2918240345	417	98.55	3	416	6	414	0.0e+00	651.3	COG0112	Glycine/serine hydroxymethyltransferase	413
2918240346	1261	64.25	764	1255	218	643	4.2e-114	376	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918240348	555	99.44	3	537	3	534	0.0e+00	587.9	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918240349	446	99.76	19	446	2	412	0.0e+00	532.5	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
2918240354	812	97.94	48	795	3	620	0.0e+00	452	COG1067	Predicted ATP-dependent protease	647
2918240356	162	94.67	1	162	4	163	1.1e-65	215.1	COG2862	Uncharacterized membrane protein YqhA	169
2918240358	205	97.09	2	205	6	205	2.4e-70	231	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
2918240360	113	98.21	2	113	2	111	3.1e-55	179.4	COG2824	Uncharacterized Zn-ribbon-containing protein	112
2918240361	322	99.09	4	322	3	327	7.2e-106	348.3	COG0142	Geranylgeranyl pyrophosphate synthase	322
2918240362	104	98.06	2	104	2	102	1.1e-44	145.5	COG0261	Ribosomal protein L21	103
2918240363	85	94.25	1	85	1	82	3.3e-42	136.7	COG0211	Ribosomal protein L27	87
2918240364	408	92.84	1	365	1	337	0.0e+00	481.2	COG0536	GTPase involved in cell partioning and DNA repair	369
2918240365	374	99.19	5	374	3	369	0.0e+00	461.2	COG0263	Glutamate 5-kinase	369
2918240366	153	90.91	1	153	8	157	9.5e-68	221.2	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
2918240371	151	91.01	1	151	13	184	3.7e-31	102.9	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918240372	212	97.12	1	203	1	202	2.8e-73	240.4	COG0288	Carbonic anhydrase	207
2918240373	232	25	5	174	96	143	1.1e-06	22.7	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
2918240375	305	98.34	4	287	2	297	2.4e-56	186.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918240376	205	97.6	1	204	4	206	6.0e-49	160.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918240377	161	83.87	2	159	18	173	1.7e-39	129.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918240378	319	95.36	1	316	12	319	7.8e-74	242.8	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918240379	813	98.11	79	813	16	795	1.9e-105	348.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918240381	310	96.28	1	310	9	319	3.7e-68	224.2	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918240382	404	47.26	220	403	6	186	4.2e-23	34	COG0477	MFS family permease	338
2918240382	404	73.89	18	256	8	290	4.2e-23	49.2	COG0477	MFS family permease	338
2918240383	386	47.52	191	384	7	188	1.5e-25	41.6	COG0477	MFS family permease	338
2918240383	386	48.3	1	200	4	188	1.5e-25	48.7	COG0477	MFS family permease	338
2918240384	818	96.39	82	818	27	720	0.0e+00	669.3	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
2918240385	318	95.98	1	318	12	321	2.2e-81	267.7	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918240386	169	86.02	3	168	16	175	2.9e-36	119.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918240387	210	73.01	5	210	66	276	1.7e-58	192.6	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
2918240388	348	97.35	1	185	2	185	6.6e-66	215.8	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
2918240388	348	98.21	184	346	3	167	2.5e-50	165.1	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2918240389	800	89.55	21	799	67	829	0.0e+00	584.1	COG3264	Small-conductance mechanosensitive channel	835
2918240390	405	96.23	1	405	11	418	4.4e-75	247.4	COG4949	Uncharacterized membrane-anchored protein	424
2918240391	476	98.33	3	475	3	473	0.0e+00	526	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918240393	327	73.41	1	271	13	277	4.7e-45	148.5	COG3177	Fic family protein	348
2918240394	397	96.96	1	382	10	392	5.7e-87	286.1	COG2814	Predicted arabinose efflux permease, MFS family	394
2918240395	172	86.02	6	170	15	174	3.0e-37	122.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918240396	318	95.67	2	312	12	320	2.6e-79	260.7	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918240397	834	96.25	82	834	28	720	0.0e+00	682.6	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
2918240398	366	100	1	366	1	372	0.0e+00	503.5	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
2918240399	194	98.41	3	193	2	187	8.6e-70	228.5	COG0193	Peptidyl-tRNA hydrolase	190
2918240400	198	97.85	3	96	3	93	4.0e-31	101	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
2918240401	246	77.99	1	246	70	317	1.5e-105	347.2	COG0462	Phosphoribosylpyrophosphate synthetase	314
2918240403	281	98.97	1	276	3	289	1.8e-91	300.6	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
2918240404	205	96.6	1	201	7	205	7.3e-63	206.3	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
2918240405	574	67.66	347	568	58	306	3.8e-25	50.3	COG0457	Tetratricopeptide (TPR) repeat	291
2918240405	574	85.6	6	348	48	362	3.8e-25	37	COG0457	Tetratricopeptide (TPR) repeat	291
2918240406	425	99.52	1	418	1	412	0.0e+00	512.3	COG0373	Glutamyl-tRNA reductase	414
2918240407	360	99.17	1	360	1	360	0.0e+00	551	COG0216	Protein chain release factor A	363
2918240408	276	94.08	2	276	14	283	2.9e-84	276.9	COG2890	Methylase of polypeptide chain release factors	280
2918240409	251	98.47	1	249	2	258	1.0e-87	287.8	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
2918240410	265	95.9	1	265	3	259	4.0e-86	282.9	COG0796	Glutamate racemase	269
2918240411	172	77.97	1	146	5	188	5.6e-03	6.3	COG3637	Opacity protein and related surface antigens	199
2918240412	212	47.76	1	193	24	151	5.4e-10	33.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918240413	495	99.14	1	471	3	461	0.0e+00	546.6	COG0415	Deoxyribodipyrimidine photolyase	461
2918240414	286	75	7	172	2	100	3.2e-23	75.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918240415	319	97.44	4	157	4	155	3.7e-37	121.5	COG1683	Uncharacterized conserved protein YbbK, DUF523 family	156
2918240415	319	98.16	158	319	1	160	4.5e-55	180.1	COG3272	Uncharacterized conserved protein YbgA, DUF1722 family	163
2918240416	328	99.1	2	327	4	332	5.9e-124	408	COG3380	Predicted NAD/FAD-dependent oxidoreductase	331
2918240417	301	98.65	3	300	1	293	2.8e-109	359.3	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
2918240418	337	97.82	1	337	3	316	2.4e-108	356.4	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
2918240419	424	94.74	2	422	17	448	3.3e-128	422.1	COG2233	Xanthine/uracil permease	451
2918240420	212	98.57	1	208	4	210	1.3e-86	284	COG0035	Uracil phosphoribosyltransferase	210
2918240421	185	96.65	7	185	4	176	1.0e-56	185.5	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
2918240424	501	99.53	4	475	2	429	1.1e-130	430.3	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
2918240426	194	86.76	1	194	21	197	3.2e-08	27.1	COG3056	Uncharacterized lipoprotein YajG	204
2918240433	206	98.67	1	206	1	223	1.2e-48	159.7	COG2135	Putative SOS response-associated peptidase YedK	226
2918240434	271	39.59	7	271	74	265	5.7e-37	122	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2918240435	194	98.44	2	191	1	189	5.9e-64	209.6	COG2119	Putative Ca2+/H+ antiporter, TMEM165/GDT1 family	190
2918240437	332	96.69	31	332	10	301	4.8e-85	279.5	COG2813	16S rRNA G1207 methylase RsmC	300
2918240438	321	91.13	7	321	25	322	6.0e-87	285.9	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918240439	560	96.48	9	553	11	558	1.3e-112	371.2	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918240442	905	99.22	11	905	6	892	0.0e+00	799	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
2918240443	537	82.88	43	528	48	352	2.2e-19	60.1	COG0457	Tetratricopeptide (TPR) repeat	291
2918240444	230	24.41	3	230	667	885	8.5e-20	64.7	COG2205	K+-sensing histidine kinase KdpD	890
2918240445	84	98.78	1	84	1	81	9.2e-19	62.1	COG2336	Antitoxin component of the MazEF toxin-antitoxin module	82
2918240446	106	90.99	1	105	10	110	5.5e-24	78.9	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
2918240447	214	81.92	1	214	12	224	5.7e-45	148.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918240448	239	90.95	20	224	18	198	5.1e-53	174.6	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918240449	695	67.26	1	221	2	151	3.5e-09	28.9	COG0132	Dethiobiotin synthetase	223
2918240449	695	99.08	374	695	1	324	2.0e-121	399	COG0280	Phosphotransacetylase	327
2918240451	161	90.96	1	161	1	161	2.7e-59	194	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
2918240452	160	96.91	1	160	4	160	3.4e-63	206.2	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
2918240453	405	98.53	6	381	3	405	2.4e-37	123.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918240454	438	49.59	134	261	122	241	3.4e-24	33.5	COG2202	PAS domain	232
2918240454	438	53.31	4	139	113	241	3.4e-24	45.9	COG2202	PAS domain	232
2918240455	242	94.8	1	242	4	240	3.3e-85	280	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
2918240456	320	98.37	4	317	3	304	2.1e-127	418.7	COG0492	Thioredoxin reductase	305
2918240459	455	85.32	46	320	47	325	1.2e-68	225.6	COG3344	Retron-type reverse transcriptase	328
2918240462	455	85.32	46	320	47	325	1.2e-68	225.6	COG3344	Retron-type reverse transcriptase	328
2918240464	282	97.86	8	282	4	277	1.3e-105	346.7	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
2918240466	188	67.05	3	187	5	179	7.5e-61	199.9	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
2918240467	276	98.23	1	276	1	277	1.0e-58	193.2	COG3725	Membrane protein required for beta-lactamase induction	282
2918240468	258	99.61	1	258	1	256	7.2e-73	239.4	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
2918240469	331	93.11	1	327	2	312	2.4e-75	248.1	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918240470	950	95.07	146	278	6	140	1.5e-50	9.9	COG4668	Mannitol/fructose-specific phosphotransferase system, IIA domain	142
2918240470	950	97.75	282	372	3	89	5.5e-21	67.6	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
2918240470	950	97.89	2	143	2	140	1.5e-50	152.9	COG4668	Mannitol/fructose-specific phosphotransferase system, IIA domain	142
2918240470	950	98.78	398	950	2	568	0.0e+00	642.6	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
2918240471	314	99.35	3	311	1	308	5.3e-104	341.8	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
2918240472	578	87.7	1	114	3	109	3.9e-55	49.1	COG1445	Phosphotransferase system fructose-specific component IIB	122
2918240472	578	93.44	117	236	3	116	3.9e-55	130.3	COG1445	Phosphotransferase system fructose-specific component IIB	122
2918240472	578	97.67	237	575	2	337	0.0e+00	457.1	COG1299	Phosphotransferase system, fructose-specific IIC component	343
2918240473	96	98.59	24	94	1	70	1.6e-32	105.7	COG3530	Uncharacterized conserved protein, DUF3820 family	71
2918240475	500	96.17	317	497	6	181	1.7e-54	178.2	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918240478	470	84.77	105	465	57	390	6.7e-60	198.2	COG0642	Signal transduction histidine kinase	336
2918240479	224	99.14	1	223	1	230	1.9e-78	257.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918240480	1030	99.8	6	1015	2	1013	0.0e+00	1093.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2918240481	387	95.38	1	373	14	385	2.6e-57	189	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918240482	244	63.38	1	130	6	95	1.1e-12	40.8	COG0727	Fe-S-cluster containining protein	132
2918240484	299	85.71	165	295	6	119	7.7e-20	64.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918240484	299	90.3	1	156	11	159	6.7e-38	123.8	COG0835	Chemotaxis signal transduction protein	165
2918240485	394	90	14	386	38	388	1.7e-39	130.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918240486	722	96.34	22	722	15	699	0.0e+00	667.4	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918240487	477	90.43	19	464	30	445	2.9e-57	188.8	COG1538	Outer membrane protein TolC	457
2918240488	7270	20.39	4511	4594	193	255	9.3e-08	12.7	COG3386	Sugar lactone lactonase YvrE	307
2918240488	7270	21.68	5525	5611	185	251	9.3e-08	1.6	COG3386	Sugar lactone lactonase YvrE	307
2918240488	7270	26.86	4847	4967	199	281	9.3e-08	3.3	COG3386	Sugar lactone lactonase YvrE	307
2918240488	7270	27.18	4174	4278	195	278	9.3e-08	10.6	COG3386	Sugar lactone lactonase YvrE	307
2918240488	7270	27.83	1373	1525	74	159	9.3e-08	1.3	COG3386	Sugar lactone lactonase YvrE	307
2918240488	7270	28.48	5938	6068	196	283	9.3e-08	3.3	COG3386	Sugar lactone lactonase YvrE	307
2918240489	517	93.45	1	517	33	546	0.0e+00	590.8	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2918240490	390	88.06	151	390	1	236	4.9e-71	233.4	COG1018	Ferredoxin-NADP reductase	266
2918240490	390	99.33	1	151	1	149	7.4e-63	205.3	COG1017	Hemoglobin-like flavoprotein	150
2918240491	168	89.02	1	167	9	162	1.9e-30	100.4	COG1495	Disulfide bond formation protein DsbB	170
2918240492	297	94.49	1	247	11	250	1.4e-84	277.4	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2918240493	672	99.82	38	608	2	569	0.0e+00	744.3	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2918240494	207	93.9	1	207	13	212	8.7e-69	225.5	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918240495	110	94.64	1	110	6	111	2.1e-39	128.2	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
2918240496	295	92.51	1	290	19	302	2.0e-98	323.9	COG0109	Polyprenyltransferase (heme O synthase)	304
2918240497	402	98.23	11	397	5	393	1.0e-129	427.2	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918240498	106	43.66	7	97	63	124	1.0e-07	26.6	COG0727	Fe-S-cluster containining protein	132
2918240499	187	93.58	3	186	7	181	7.8e-38	124.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918240501	157	96.69	7	157	4	149	1.5e-37	123.2	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
2918240502	301	97.01	7	300	1	292	2.4e-40	133.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918240503	130	92.97	2	129	8	126	6.3e-25	81.9	COG3755	Uncharacterized conserved protein YecT, DUF1311 family	127
2918240504	373	99.7	1	342	1	334	8.9e-128	420.4	COG2603	tRNA 2-selenouridine synthase SelU, contains rhodanese domain	334
2918240505	344	98.84	1	344	4	345	0.0e+00	481.8	COG0709	Selenophosphate synthase	346
2918240506	284	94.02	1	284	15	297	6.0e-85	279.6	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
2918240507	264	91.47	1	252	12	247	9.7e-78	255.2	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
2918240508	275	91.55	1	275	23	282	9.9e-76	249	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
2918240509	255	88.73	1	254	32	283	9.3e-72	236	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
2918240510	296	87.58	9	295	27	294	1.0e-65	216	COG3781	Predicted membrane chloride channel, bestrophin family	306
2918240511	99	93	2	99	6	98	2.9e-33	108.3	COG3657	Putative component of the toxin-antitoxin plasmid stabilization module	100
2918240512	101	93	1	97	6	98	7.1e-32	103.7	COG3636	DNA-binding prophage protein	100
2918240516	349	99.43	1	341	1	347	0.0e+00	497.4	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
2918240517	377	97.58	9	376	1	363	0.0e+00	572.7	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
2918240518	111	92.78	15	111	7	96	5.2e-33	107.4	COG1862	Preprotein translocase subunit YajC	97
2918240519	620	99.43	77	620	3	522	0.0e+00	587.6	COG0342	Preprotein translocase subunit SecD	506
2918240520	302	94.16	1	296	8	297	8.9e-105	344.4	COG0341	Preprotein translocase subunit SecF	305
2918240521	179	98.88	1	179	1	177	1.1e-77	254.5	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
2918240522	272	99.61	1	263	1	258	5.3e-87	285.8	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2918240523	252	97.98	1	252	2	244	1.4e-90	297.6	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
2918240524	261	92.86	1	190	4	185	1.1e-83	273.7	COG1045	Serine acetyltransferase	194
2918240525	163	92.67	1	148	1	139	5.5e-51	166.8	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918240526	404	99.48	3	388	2	385	0.0e+00	537.2	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
2918240527	128	94.7	1	128	5	147	1.5e-52	171.7	COG0822	NifU homolog involved in Fe-S cluster formation	150
2918240528	107	98.18	1	107	3	110	5.1e-42	136.7	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2918240529	170	98.28	4	170	2	172	1.2e-33	111	COG1076	DnaJ-domain-containing proteins 1	174
2918240530	620	99.34	10	604	4	605	0.0e+00	647.1	COG0443	Molecular chaperone DnaK (HSP70)	579
2918240531	113	93.2	1	104	6	101	3.8e-25	82.1	COG0633	Ferredoxin	102
2918240532	66	100	3	66	1	64	2.0e-34	112.4	COG2975	Fe-S-cluster formation regulator IscX/YfhJ	64
2918240533	141	98.52	2	136	2	134	1.8e-62	203.5	COG0105	Nucleoside diphosphate kinase	135
2918240534	381	100	7	358	1	349	0.0e+00	487.6	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
2918240535	252	98.4	2	252	4	249	1.1e-71	235.6	COG3063	Tfp pilus assembly protein PilF	250
2918240536	343	98.97	13	311	2	289	1.1e-51	170.2	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
2918240537	369	98.65	7	364	2	366	0.0e+00	501.6	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
2918240538	429	99.07	2	427	2	429	0.0e+00	476.4	COG0124	Histidyl-tRNA synthetase	429
2918240539	213	97.6	1	210	5	207	3.6e-60	197.6	COG2976	Putative negative regulator of RcsB-dependent stress response	207
2918240540	389	89.39	10	386	38	391	1.8e-50	166.2	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
2918240541	487	99.55	1	456	2	444	0.0e+00	580.8	COG1160	Predicted GTPases	444
2918240542	382	95.2	2	382	13	389	5.7e-105	345.8	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918240543	263	97.12	8	263	2	271	6.7e-60	196.8	COG0388	Predicted amidohydrolase	274
2918240544	850	38.86	627	850	366	597	1.6e-115	240.5	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
2918240544	850	50.75	308	637	4	306	1.6e-115	139.5	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
2918240545	749	95.73	2	749	33	750	0.0e+00	826.8	COG4774	Outer membrane receptor for monomeric catechols	750
2918240546	226	99.13	1	226	3	229	3.7e-103	338.4	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
2918240547	248	59.21	8	245	74	269	8.6e-33	107.7	COG0790	TPR repeat	292
2918240549	387	95.7	4	387	17	394	6.8e-107	351.8	COG0019	Diaminopimelate decarboxylase	394
2918240550	385	99.36	1	364	1	312	3.8e-127	418.2	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
2918240551	217	89.69	2	217	20	219	1.4e-74	244.5	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
2918240552	303	97.33	1	296	9	300	3.1e-90	296.7	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
2918240553	237	90.58	15	237	15	216	2.3e-69	227.3	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
2918240554	132	95.83	11	130	2	116	3.2e-33	108.4	COG4683	Uncharacterized protein	120
2918240555	104	46.38	27	86	5	36	1.1e-05	19.2	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2918240556	527	99.43	1	526	4	528	0.0e+00	857.1	COG4108	Peptide chain release factor RF-3	528
2918240557	359	96.3	1	359	14	377	1.4e-101	334.7	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918240558	113	90.52	1	112	10	114	7.7e-38	123.3	COG3450	Predicted enzyme of the cupin superfamily	116
2918240559	468	97.42	29	419	6	383	7.5e-62	203.9	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918240560	269	75.76	127	269	27	126	2.6e-18	59.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918240561	318	20.26	232	301	51	96	2.0e-02	1.8	COG0785	Cytochrome c biogenesis protein CcdA	220
2918240561	318	45.37	2	155	43	145	2.0e-02	7.4	COG0785	Cytochrome c biogenesis protein CcdA	220
2918240562	322	97.5	1	312	3	314	3.7e-117	385.4	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918240563	322	96.62	3	316	1	314	1.8e-122	402.6	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918240564	308	95.64	15	307	12	296	3.6e-101	332.3	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918240565	336	99.69	1	336	1	317	3.2e-127	418.7	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918240566	531	95.33	1	531	21	571	1.1e-119	395.4	COG0747	ABC-type transport system, periplasmic component	556
2918240568	541	97.23	1	541	10	571	6.8e-130	429	COG0747	ABC-type transport system, periplasmic component	556
2918240569	238	94.04	8	235	15	235	2.0e-79	260.6	COG3471	Predicted secreted (periplasmic) protein	235
2918240570	419	84.01	11	415	56	386	3.2e-41	136.3	COG0642	Signal transduction histidine kinase	336
2918240571	186	95.6	3	185	9	182	7.9e-84	274.3	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918240572	1016	99.7	2	1005	2	1012	0.0e+00	1049.1	COG0841	Multidrug efflux pump subunit AcrB	1009
2918240573	384	96.67	1	370	7	383	1.2e-66	219.8	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918240574	365	97.81	1	365	6	363	0.0e+00	461	COG3490	Uncharacterized protein	366
2918240575	354	100	1	354	1	359	7.6e-113	371.7	COG3489	Predicted periplasmic lipoprotein	359
2918240576	473	98.13	2	473	10	481	0.0e+00	759	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
2918240577	445	99.78	4	445	1	445	0.0e+00	672.9	COG3487	Uncharacterized iron-regulated protein	446
2918240578	683	63.95	158	682	219	642	4.4e-120	395.9	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918240580	198	97.56	1	197	2	201	2.0e-79	260.7	COG0605	Superoxide dismutase	204
2918240581	199	99.01	1	199	1	200	1.1e-71	235.1	COG1279	Arginine exporter protein ArgO	202
2918240582	296	97.34	2	293	1	293	2.0e-42	140.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918240583	331	98.44	1	329	2	317	2.1e-58	192.5	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918240584	275	17.64	64	274	704	909	6.6e-07	21.3	COG1196	Chromosome segregation ATPase	1163
2918240585	349	97.8	1	349	3	357	7.3e-111	365.2	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918240586	100	77.12	1	100	12	102	1.3e-16	55.1	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918240587	189	98.45	1	189	1	190	3.8e-67	220.4	COG3124	Acyl carrier protein phosphodiesterase	193
2918240588	262	64.37	10	260	18	185	4.4e-31	102.6	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918240589	251	86.01	3	251	36	287	1.5e-69	228.8	COG3176	Putative hemolysin	292
2918240591	361	91.83	2	360	7	377	4.2e-42	139.1	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918240594	385	85.36	2	378	65	478	1.4e-76	252.2	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918240595	192	96.94	2	191	3	192	3.5e-47	155	COG0693	Putative intracellular protease/amidase	188
2918240596	313	98.72	4	310	3	311	8.6e-57	186.8	COG0679	Predicted permease	311
2918240597	453	97.62	1	453	4	454	0.0e+00	616.7	COG1113	L-asparagine transporter and related permeases	462
2918240598	339	91.54	1	301	23	325	6.6e-65	213.6	COG0530	Ca2+/Na+ antiporter	320
2918240599	124	40.32	12	124	82	181	1.3e-55	183.4	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
2918240600	481	98.96	1	481	4	481	0.0e+00	680.1	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
2918240601	483	98.96	1	481	5	480	0.0e+00	610.8	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918240602	95	98.96	1	95	1	95	5.7e-30	98	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
2918240604	345	98.53	5	344	2	337	0.0e+00	517.5	COG1077	Actin-like ATPase involved in cell morphogenesis	342
2918240605	342	91.26	1	272	17	277	2.3e-75	247.5	COG1792	Cell shape-determining protein MreC	284
2918240606	162	94.01	2	162	6	162	1.9e-44	146	COG2891	Cell shape-determining protein MreD	167
2918240607	199	96.91	1	191	3	190	1.1e-66	218.2	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
2918240608	485	98.57	2	485	2	483	0.0e+00	602.6	COG1530	Ribonuclease G or E	487
2918240609	1271	99.37	2	1271	5	1267	0.0e+00	935.2	COG3164	Uncharacterized conserved protein YhdP, contains DUF3971 and AsmA2 domains	1271
2918240610	283	97.12	1	278	3	272	2.5e-72	237.5	COG0388	Predicted amidohydrolase	274
2918240611	479	99.12	19	477	4	455	0.0e+00	521.8	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2918240612	173	85.56	2	173	26	185	2.3e-65	213.9	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
2918240613	448	99.34	14	448	3	455	3.3e-121	399.5	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2918240615	458	99.35	2	457	2	460	0.0e+00	626.1	COG0114	Fumarate hydratase class II	462
2918240617	203	98.54	1	203	2	203	1.7e-78	257.7	COG0605	Superoxide dismutase	204
2918240618	302	97.06	44	302	7	270	2.8e-48	158.8	COG0428	Zinc transporter ZupT	266
2918240619	106	90.11	2	92	8	89	1.4e-17	57.8	COG5606	Predicted DNA-binding protein, XRE-type HTH domain	91
2918240620	123	91.38	1	121	7	112	2.7e-29	96.2	COG4679	Phage-related protein	116
2918240621	90	97.75	1	89	1	87	3.2e-29	95.3	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
2918240622	284	98.95	1	284	1	283	3.3e-113	372.1	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
2918240623	155	88.16	4	154	17	150	1.9e-38	125.9	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
2918240624	102	87.27	1	101	1	96	9.2e-37	120.2	COG1544	Ribosome-associated translation inhibitor RaiA	110
2918240625	503	99.78	1	503	1	447	0.0e+00	579.5	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
2918240626	241	99.18	1	241	3	243	1.8e-120	395	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
2918240627	175	92.49	1	175	7	166	1.2e-45	149.5	COG1934	Lipopolysaccharide export system protein LptA	173
2918240628	190	94.65	6	190	8	184	2.8e-47	155.2	COG3117	Lipopolysaccharide export system protein LptC	188
2918240629	174	98.82	5	174	2	169	1.1e-71	234.2	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
2918240630	324	98.51	7	207	4	202	6.7e-79	258	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
2918240631	269	97.72	1	262	4	260	1.5e-106	349.8	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
2918240632	265	96.63	1	265	7	264	1.6e-95	313.7	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2918240633	161	43.24	1	160	1	160	1.5e-44	146.9	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2918240634	217	97.03	1	205	6	201	8.1e-52	170.3	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
2918240635	100	97.98	1	100	1	97	8.1e-16	52.6	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
2918240636	79	97.5	1	79	1	78	1.8e-31	102.6	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
2918240637	421	99.29	1	421	1	418	0.0e+00	626.6	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
2918240638	211	74.74	1	210	2	220	4.4e-68	223.9	COG0040	ATP phosphoribosyltransferase	290
2918240639	441	96.27	7	438	13	425	0.0e+00	584.8	COG0141	Histidinol dehydrogenase	425
2918240640	348	97.51	4	348	2	353	1.4e-104	344.2	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2918240641	216	91.29	1	216	6	225	9.4e-54	176.7	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918240642	426	96.72	24	424	11	393	0.0e+00	473.7	COG2807	Cyanate permease	395
2918240643	156	88.24	1	122	6	125	4.0e-10	34.2	COG3631	Ketosteroid isomerase-related protein	133
2918240644	116	87.37	9	101	4	86	5.6e-29	94.1	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
2918240645	335	98.51	1	335	3	332	0.0e+00	446.2	COG3081	Nucleoid-associated protein YejK (function unknown)	335
2918240646	93	96.81	2	93	2	92	1.9e-28	93	COG0776	Bacterial nucleoid DNA-binding protein	94
2918240647	318	97.95	26	316	2	287	2.9e-116	382.3	COG3129	23S rRNA A1618 N6-methylase RlmF	292
2918240648	948	99.66	1	947	2	881	0.0e+00	1257.2	COG0525	Valyl-tRNA synthetase	877
2918240650	142	98.61	1	142	1	142	1.1e-38	126.9	COG2927	DNA polymerase III, chi subunit	144
2918240651	496	97.74	1	495	11	486	0.0e+00	594.7	COG0260	Leucyl aminopeptidase	485
2918240652	371	98.9	1	358	3	363	2.7e-81	267.9	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
2918240653	353	99.18	1	353	1	362	1.3e-83	275.5	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
2918240654	162	79.55	5	162	19	158	6.2e-29	95.2	COG1714	Uncharacterized membrane protein YckC, RDD family	172
2918240655	70	97.01	4	69	2	66	1.2e-32	106.1	COG1278	Cold shock protein, CspA family	67
2918240656	373	98.96	1	373	2	382	3.0e-119	392.6	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
2918240657	458	26.55	3	93	52	124	1.3e-125	8.2	COG1760	L-serine deaminase	262
2918240657	458	100	172	454	1	275	1.3e-125	402.7	COG1760	L-serine deaminase	262
2918240658	951	28.77	199	382	209	351	0.0e+00	18.4	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2918240658	951	94.77	445	921	25	495	0.0e+00	725.2	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2918240659	127	93.89	1	124	7	129	6.8e-45	146.4	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
2918240660	401	99.26	1	400	2	404	0.0e+00	502.2	COG0786	Na+/glutamate symporter	404
2918240661	502	99.81	1	502	1	514	0.0e+00	668.7	COG3283	Transcriptional regulator of aromatic amino acids metabolism	511
2918240663	309	99.68	1	301	1	311	2.5e-124	408.7	COG0549	Carbamate kinase	312
2918240664	336	99.04	2	334	3	310	0.0e+00	432.6	COG0078	Ornithine carbamoyltransferase	310
2918240665	418	99.75	4	416	2	407	0.0e+00	511.1	COG2235	Arginine deiminase	409
2918240666	475	94.72	2	464	13	478	2.9e-82	270.9	COG0531	Amino acid transporter	466
2918240667	475	93.5	1	464	12	471	9.3e-79	259.5	COG0531	Amino acid transporter	466
2918240668	170	98.32	9	126	2	118	6.5e-29	94.8	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
2918240669	201	97.96	2	195	2	193	5.1e-55	180.5	COG3230	Heme oxygenase	196
2918240670	851	93.96	51	847	45	791	4.4e-109	360.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918240671	320	95.36	9	319	9	316	1.1e-61	202.7	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918240672	170	84.41	1	168	14	170	1.5e-34	113.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918240673	333	98.21	2	333	2	330	0.0e+00	452.9	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
2918240674	608	98.79	2	603	4	574	0.0e+00	662.5	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918240675	319	97.5	1	316	8	319	2.8e-107	352.7	COG0837	Glucokinase	320
2918240676	241	98.71	6	237	2	230	2.9e-76	250.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918240677	484	84.52	116	484	57	389	4.7e-46	152.7	COG0642	Signal transduction histidine kinase	336
2918240678	408	96.13	1	397	9	381	6.1e-94	309.3	COG2942	Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family	388
2918240679	428	98.42	2	428	4	439	2.4e-49	163.3	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918240680	302	95.3	10	301	8	291	1.4e-74	245.3	COG1175	ABC-type sugar transport system, permease component	295
2918240681	281	96.82	3	280	10	283	5.0e-76	250.1	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918240682	384	99.71	1	360	1	349	0.0e+00	476.4	COG3839	ABC-type sugar transport system, ATPase component	338
2918240683	447	96.58	2	447	16	439	0.0e+00	592.4	COG3659	Carbohydrate-selective porin OprB	439
2918240684	284	97.25	4	283	4	286	2.8e-75	247.3	COG0676	D-hexose-6-phosphate mutarotase	287
2918240685	290	98.94	3	282	3	281	1.4e-88	291	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918240686	489	98.77	3	488	5	484	0.0e+00	625.5	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
2918240687	237	95.42	12	237	2	230	1.1e-57	189.7	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
2918240688	224	98.1	15	224	3	209	3.1e-73	239.9	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
2918240689	557	99.03	31	464	2	410	2.0e-130	429.7	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918240690	275	52.22	54	274	140	304	3.9e-43	142.4	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2918240691	459	99.1	11	452	3	443	0.0e+00	540.2	COG1570	Exonuclease VII, large subunit	440
2918240692	251	97.3	7	251	6	257	2.3e-27	90.3	COG0730	Uncharacterized membrane protein YfcA	258
2918240694	489	87.61	1	209	7	197	2.0e-118	174.2	COG0516	IMP dehydrogenase/GMP reductase	170
2918240694	489	100	256	478	1	218	2.0e-118	219.4	COG0516	IMP dehydrogenase/GMP reductase	170
2918240695	525	98.99	7	206	2	197	1.7e-74	243.2	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2918240695	525	99.68	207	525	2	316	0.0e+00	504.8	COG0519	GMP synthase, PP-ATPase domain/subunit	315
2918240696	460	99.38	5	460	1	481	1.9e-87	288.9	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2918240697	159	96.08	6	154	6	152	3.1e-51	167.7	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2918240698	463	94.93	4	461	13	461	0.0e+00	586	COG4623	Membrane-bound lytic murein transglycosylase MltF	473
2918240699	1299	93.92	157	979	3	713	0.0e+00	919.5	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
2918240699	1299	99.18	1042	1299	2	243	2.1e-91	299.4	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
2918240700	103	93.58	1	103	5	106	9.0e-41	132.9	COG3323	Uncharacterized protein	109
2918240701	252	95.37	4	251	3	249	6.7e-84	275.6	COG0805	Sec-independent protein secretion pathway component TatC	255
2918240702	100	69.15	1	98	1	65	8.0e-19	62.4	COG1826	Sec-independent protein translocase protein TatA	94
2918240703	77	76.6	1	77	1	72	5.0e-20	66.2	COG1826	Sec-independent protein translocase protein TatA	94
2918240704	321	78.4	1	276	4	257	6.8e-28	92.5	COG3156	Type II secretory pathway, component PulK	323
2918240705	683	99.2	8	682	5	622	0.0e+00	541.8	COG3211	Secreted phosphatase, PhoX family	616
2918240706	546	44.32	80	450	49	282	2.9e-10	33.4	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
2918240708	653	93.51	4	639	30	605	0.0e+00	498.3	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
2918240709	482	94.49	1	482	28	507	0.0e+00	544.1	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2918240710	400	99.75	1	399	1	397	8.0e-123	404.4	COG1459	Type II secretory pathway, component PulF	397
2918240711	144	98.72	2	142	3	156	3.0e-34	113.2	COG2165	Type II secretory pathway, pseudopilin PulG	149
2918240712	145	66.03	1	142	5	107	4.3e-10	34.5	COG2165	Type II secretory pathway, pseudopilin PulG	149
2918240713	122	55.77	1	115	4	90	1.0e-14	49.8	COG2165	Type II secretory pathway, pseudopilin PulG	149
2918240714	196	73.63	1	187	1	148	2.7e-09	31.6	COG4795	Type II secretory pathway, component PulJ	194
2918240719	560	95.54	6	548	8	542	2.2e-105	347.7	COG2831	Hemolysin activation/secretion protein	554
2918240720	182	52	3	182	36	191	3.2e-44	145.9	COG3034	Murein L,D-transpeptidase YafK	298
2918240721	184	96.58	29	166	3	143	1.2e-24	81.1	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2918240722	199	49.42	14	172	15	99	1.2e-13	45.4	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918240723	174	90.4	1	173	12	171	2.4e-64	210.3	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2918240724	65	68.92	3	62	4	54	5.4e-23	75.3	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
2918240725	155	33.63	1	148	99	174	1.1e-09	29.9	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
2918240726	393	99.75	1	393	1	393	0.0e+00	655.5	COG0027	Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	394
2918240727	434	45.95	246	432	18	193	8.3e-39	31.8	COG0477	MFS family permease	338
2918240727	434	74.93	17	294	6	292	8.3e-39	98.2	COG0477	MFS family permease	338
2918240728	405	83.92	52	405	62	416	9.5e-95	312.1	COG4536	Mg2+ and Co2+ transporter CorB, contains DUF21, CBS pair, and CorC-HlyC domains	423
2918240729	269	97.74	6	269	6	264	1.7e-84	278	COG4137	ABC-type uncharacterized transport system, permease component	265
2918240730	458	98.89	1	457	1	447	0.0e+00	642.5	COG0541	Signal recognition particle GTPase	451
2918240731	83	87.78	1	83	1	79	7.4e-34	110.1	COG0228	Ribosomal protein S16	87
2918240732	178	97.13	2	178	4	172	9.0e-56	182.5	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
2918240733	250	98.36	4	247	1	240	4.1e-103	338	COG0336	tRNA G37 N-methylase TrmD	240
2918240734	116	95.08	1	115	6	121	7.8e-51	165.7	COG0335	Ribosomal protein L19	115
2918240735	136	75.8	1	136	11	129	2.7e-46	151.6	COG1607	Acyl-CoA hydrolase	157
2918240736	298	98.33	1	298	5	299	9.4e-124	406.9	COG4974	Site-specific recombinase XerD	300
2918240737	253	95.18	1	246	6	242	4.2e-38	125.7	COG1651	Protein-disulfide isomerase	244
2918240738	434	77.78	350	433	8	77	5.0e-06	20.1	COG3830	ACT domain, binds amino acids and other small ligands	90
2918240738	434	98.8	1	322	2	331	2.6e-112	369.7	COG0460	Homoserine dehydrogenase	333
2918240739	469	100	1	462	1	419	0.0e+00	454.6	COG0498	Threonine synthase	411
2918240740	106	61.54	1	95	4	75	1.4e-15	52.2	COG2963	Transposase and inactivated derivatives	116
2918240741	111	57.67	4	104	40	133	2.7e-15	50.7	COG3436	Transposase	157
2918240742	511	98.77	96	257	3	163	2.0e-40	132.3	COG3436	Transposase	157
2918240743	71	38.78	7	67	20	57	1.7e-04	15.2	COG5416	Uncharacterized integral membrane protein	98
2918240744	146	21.63	1	139	6	106	1.6e-05	18.5	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918240747	399	98.75	1	399	6	401	0.0e+00	449	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918240748	180	99.45	1	179	1	180	1.1e-71	234.8	COG4681	Uncharacterized conserved protein YaeQ, suppresses RfaH defect	181
2918240749	569	96.83	31	546	2	489	0.0e+00	543.1	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
2918240750	368	96.69	1	364	3	353	2.3e-119	393.3	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918240751	110	97.3	1	110	1	108	2.7e-37	122	COG4226	Predicted nuclease of the RNAse H fold, HicB family	111
2918240753	234	97.78	1	233	1	220	8.2e-75	245.1	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
2918240754	535	89.18	55	535	47	425	3.6e-85	281.1	COG0840	Methyl-accepting chemotaxis protein	408
2918240755	170	86.67	3	164	17	159	1.2e-27	90.8	COG0835	Chemotaxis signal transduction protein	165
2918240756	417	97.04	2	265	5	266	6.0e-64	210.1	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918240757	221	86.67	61	221	16	158	1.3e-23	77.7	COG0835	Chemotaxis signal transduction protein	165
2918240758	763	16.05	3	169	3	123	0.0e+00	79	COG0643	Chemotaxis protein histidine kinase CheA	716
2918240758	763	53.18	129	640	347	747	0.0e+00	449.7	COG0643	Chemotaxis protein histidine kinase CheA	716
2918240758	763	62.09	631	760	6	118	3.8e-08	27.6	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918240759	337	97.73	1	337	2	345	1.1e-96	318.4	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918240760	334	69.2	5	334	131	431	3.9e-107	352.9	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918240761	304	99.16	67	304	1	237	6.2e-108	354.1	COG1186	Protein chain release factor B	239
2918240762	500	98.23	1	500	9	508	0.0e+00	707.1	COG1190	Lysyl-tRNA synthetase (class II)	502
2918240763	226	98.53	10	221	2	202	3.8e-48	158.4	COG3226	DNA-binding transcriptional regulator YbjK	204
2918240765	425	97.93	1	417	10	434	0.0e+00	488.7	COG3930	Uncharacterized protein	434
2918240766	307	75	25	295	69	299	2.3e-27	90.4	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
2918240768	262	88.94	12	249	22	198	1.7e-49	162.1	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918240771	875	99.34	1	875	7	913	0.0e+00	1101	COG2352	Phosphoenolpyruvate carboxylase	910
2918240772	215	99.46	1	215	1	184	1.9e-70	231.2	COG0563	Adenylate kinase or related kinase	178
2918240773	224	99.1	2	223	2	220	6.1e-66	217	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
2918240775	289	98.12	6	282	3	263	3.5e-67	221.3	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
2918240776	276	90.38	2	275	7	269	2.5e-81	267.2	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
2918240777	229	69.67	12	229	91	299	5.7e-69	227.8	COG3921	Uncharacterized conserved protein	300
2918240780	172	84.75	1	170	6	155	2.4e-38	125.7	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918240781	427	99.47	47	426	2	378	0.0e+00	443.3	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918240782	332	96.69	1	328	9	329	2.5e-103	340.2	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918240783	266	91.37	1	254	3	256	1.1e-50	166.6	COG0388	Predicted amidohydrolase	274
2918240784	266	97.65	1	262	3	251	2.6e-46	152.4	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
2918240785	299	93.02	3	292	2	281	5.6e-46	152	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918240786	223	92.92	10	214	11	207	1.9e-43	142.7	COG0684	Regulator of RNase E activity RraA	210
2918240787	349	83.13	1	328	5	280	1.0e-39	131.1	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918240788	201	88.46	1	180	10	170	3.6e-14	47.1	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
2918240789	427	98.15	48	427	5	376	2.3e-99	326.9	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918240790	209	93.3	1	209	8	202	3.9e-23	77.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918240791	366	95.64	1	355	10	382	1.4e-51	170.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918240792	1019	99.9	4	1016	1	1013	0.0e+00	920.6	COG0841	Multidrug efflux pump subunit AcrB	1009
2918240794	134	85.53	1	134	13	148	9.8e-41	133.2	COG3126	Uncharacterized lipoprotein YbaY	158
2918240795	832	99.38	3	822	2	806	0.0e+00	979.6	COG2937	Glycerol-3-phosphate O-acyltransferase	810
2918240796	69	94.03	4	69	2	64	7.7e-31	100.5	COG1278	Cold shock protein, CspA family	67
2918240798	270	49.82	20	269	42	180	1.4e-08	29.8	COG0500	SAM-dependent methyltransferase	257
2918240799	383	96.17	2	383	15	416	6.8e-101	332.7	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918240800	863	81.78	359	781	6	418	5.6e-59	194.3	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2918240800	863	100	1	296	1	305	1.7e-88	290.7	COG5309	Exo-beta-1,3-glucanase,  GH17 family	305
2918240801	269	94.7	1	263	11	260	3.0e-107	352.2	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
2918240802	136	91.67	2	136	9	140	3.7e-45	147.4	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
2918240803	401	99.27	1	401	2	407	0.0e+00	461.8	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
2918240804	344	95.96	58	343	11	271	4.6e-89	292.9	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
2918240805	115	97.44	1	115	2	115	5.6e-35	114.5	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2918240806	548	97.71	1	445	10	435	2.3e-112	370	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
2918240807	398	97.98	2	398	5	392	1.9e-99	327.8	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918240808	900	99.19	13	891	4	863	0.0e+00	1090.7	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
2918240809	260	99.35	1	253	2	309	3.6e-98	322.9	COG0024	Methionine aminopeptidase	255
2918240811	245	89.84	1	245	6	235	5.5e-106	347.8	COG0052	Ribosomal protein S2	252
2918240812	287	99.66	1	284	1	296	4.7e-99	325.6	COG0264	Translation elongation factor EF-Ts	296
2918240813	247	99.16	9	244	2	237	8.4e-96	314.5	COG0528	Uridylate kinase	238
2918240814	185	98.93	1	185	3	187	7.6e-69	225.4	COG0233	Ribosome recycling factor	187
2918240815	251	94.84	1	240	14	252	1.5e-95	313.8	COG0020	Undecaprenyl pyrophosphate synthase	245
2918240816	271	97.82	1	267	1	269	2.1e-66	218.8	COG0575	CDP-diglyceride synthetase	265
2918240817	393	98.7	1	392	2	382	0.0e+00	546.1	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
2918240818	450	49.25	3	222	3	200	5.4e-108	195	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
2918240818	450	66.17	193	450	135	400	5.4e-108	167.7	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
2918240819	782	99.61	1	782	4	774	0.0e+00	825.2	COG4775	Outer membrane protein assembly factor BamA	766
2918240820	167	97.65	1	166	4	169	1.0e-31	104.8	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
2918240821	351	99.11	2	338	3	337	1.4e-128	423	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
2918240822	146	95.95	1	146	3	144	6.0e-56	182.8	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2918240823	258	98.85	1	258	3	259	9.7e-109	357	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
2918240824	375	99.21	3	374	3	379	0.0e+00	466.3	COG0763	Lipid A disaccharide synthetase	381
2918240825	207	95.54	13	205	2	194	1.1e-67	222.5	COG0164	Ribonuclease HII	199
2918240826	1174	99.83	2	1172	2	1156	0.0e+00	1444.8	COG0587	DNA polymerase III, alpha subunit	1139
2918240827	315	98.11	2	315	3	313	0.0e+00	492.5	COG0825	Acetyl-CoA carboxylase alpha subunit	317
2918240828	431	73.7	12	278	26	252	8.2e-59	193.3	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
2918240829	542	99.63	2	542	2	534	0.0e+00	840.8	COG0504	CTP synthase (UTP-ammonia lyase)	533
2918240830	281	98.92	1	280	3	278	0.0e+00	451.4	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
2918240831	429	99.53	1	429	1	423	0.0e+00	659.1	COG0148	Enolase	423
2918240832	93	77.12	1	93	23	113	4.9e-27	88.6	COG2919	Cell division protein FtsB	117
2918240833	215	88.79	1	214	18	223	5.5e-68	223	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
2918240834	298	96.35	5	295	9	298	4.7e-76	250.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918240835	370	99.73	2	370	2	366	0.0e+00	568.4	COG1062	Zn-dependent alcohol dehydrogenase	366
2918240836	284	96.91	1	284	8	321	1.8e-87	288.1	COG0627	S-formylglutathione hydrolase FrmB	316
2918240837	157	96.86	1	157	1	154	1.2e-72	237.6	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
2918240838	352	37.09	2	180	24	181	1.0e-82	181.2	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
2918240838	352	39.67	176	348	249	417	1.0e-82	90.2	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
2918240839	249	99.61	1	246	1	255	7.2e-82	269.1	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
2918240840	225	94.79	17	224	4	203	5.5e-77	252.4	COG2518	Protein-L-isoaspartate O-methyltransferase	209
2918240841	262	95.89	35	262	4	306	3.0e-52	169.9	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2918240842	335	84.46	11	334	47	334	1.8e-105	347.6	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918240845	107	90.41	1	65	5	70	9.4e-19	61.7	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2918240846	856	99.77	2	854	3	854	0.0e+00	1049.4	COG0249	DNA mismatch repair ATPase MutS	843
2918240847	160	93.87	1	160	8	160	2.6e-56	184.1	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
2918240848	355	98.28	1	281	6	291	1.9e-127	418.6	COG0468	RecA/RadA recombinase	279
2918240849	141	79.65	1	140	26	162	8.2e-39	127.6	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
2918240850	372	95.61	67	276	4	199	7.5e-51	166.8	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2918240853	236	95.24	1	233	2	221	3.2e-94	309.2	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
2918240854	216	97.63	4	214	2	207	1.7e-56	185.6	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918240855	120	94.31	3	120	3	118	1.1e-45	148.9	COG0818	Diacylglycerol kinase	123
2918240856	308	97.34	3	298	2	294	2.7e-67	222	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918240857	259	98.88	1	256	4	268	1.0e-64	212.9	COG1018	Ferredoxin-NADP reductase	266
2918240858	231	94.23	1	163	4	150	5.9e-55	179.5	COG1720	tRNA (Thr-GGU) A37 N-methylase	156
2918240859	153	98.71	1	153	1	153	2.1e-68	223.4	COG4807	Uncharacterized conserved protein YehS, DUF1456 family	155
2918240860	236	95.12	3	236	2	235	1.8e-39	129.9	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2918240861	152	69.14	4	132	46	157	4.9e-13	44	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918240863	445	98.87	8	445	3	438	0.0e+00	461.5	COG0621	tRNA A37 methylthiotransferase MiaB	437
2918240864	632	97.61	4	632	16	627	0.0e+00	881.9	COG3158	K+ transporter	627
2918240865	430	85.25	6	427	65	457	1.9e-115	381.2	COG3946	Type IV secretory pathway, VirJ component	456
2918240866	880	96.91	20	347	4	317	1.2e-55	183.7	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2918240866	880	99.26	340	880	5	541	0.0e+00	626.9	COG2898	Lysylphosphatidylglycerol synthetase, C-terminal domain, DUF2156 family	538
2918240870	354	97.06	4	350	1	363	2.0e-105	347.4	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918240872	571	99.05	1	567	1	522	0.0e+00	702.7	COG0442	Prolyl-tRNA synthetase	500
2918240874	139	82.98	5	133	24	140	4.8e-29	95.4	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2918240875	68	95.83	1	68	4	72	2.5e-23	76.8	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
2918240876	197	97.01	129	194	2	66	6.1e-28	90.9	COG1278	Cold shock protein, CspA family	67
2918240877	157	98.09	1	155	3	156	2.7e-56	184.4	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
2918240878	112	70.59	24	111	9	80	5.9e-19	61.9	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918240879	73	80.49	1	73	8	73	2.0e-23	76.8	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
2918240880	591	99.83	2	587	1	585	0.0e+00	852.5	COG0173	Aspartyl-tRNA synthetase	585
2918240881	248	99.59	1	242	1	242	7.2e-103	337.8	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
2918240882	174	95.65	5	163	1	154	8.0e-60	195.7	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
2918240883	205	99	1	203	2	200	9.0e-69	225.4	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
2918240884	348	99.1	4	335	2	330	0.0e+00	525	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
2918240885	150	94.24	7	142	5	135	5.0e-48	156.9	COG0824	Acyl-CoA thioesterase FadM	137
2918240886	231	98.61	14	229	2	214	1.5e-73	241.8	COG0811	Biopolymer transport protein ExbB/TolQ	216
2918240887	150	93.53	1	150	7	136	2.4e-41	135.3	COG0848	Biopolymer transport protein ExbD	137
2918240888	358	72.63	125	328	50	248	1.4e-07	22.6	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2918240889	433	96.04	8	432	18	429	0.0e+00	446.5	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2918240890	166	60.8	7	165	74	194	2.3e-43	143.1	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918240891	212	75	1	212	64	261	1.2e-56	187.1	COG1729	Periplasmic TolA-binding protein (function unknown)	262
2918240893	215	99.08	2	211	3	217	1.1e-45	151	COG0602	Organic radical activating enzyme	212
2918240894	224	98.2	2	224	2	219	5.5e-82	268.9	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
2918240896	319	95.22	5	319	15	313	5.1e-119	391.4	COG3965	Predicted Co/Zn/Cd cation transporter, cation efflux family	314
2918240897	708	85.41	259	708	63	425	9.9e-112	368.3	COG0840	Methyl-accepting chemotaxis protein	408
2918240898	450	93.29	7	449	9	467	6.4e-73	240.2	COG0531	Amino acid transporter	466
2918240899	505	97.93	5	500	6	477	5.9e-65	214.3	COG5339	Uncharacterized conserved protein YdgA, DUF945 family	479
2918240900	352	96.31	7	342	12	324	3.9e-123	404.9	COG0379	Quinolinate synthase	324
2918240901	477	98.35	1	477	8	484	0.0e+00	511	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2918240902	79	95	2	79	3	78	4.0e-22	72.5	COG0425	TusA-related sulfurtransferase	78
2918240903	356	96.39	4	355	3	349	6.3e-83	273.1	COG0628	Predicted PurR-regulated permease PerM	355
2918240904	157	97.45	1	156	3	155	4.2e-58	190	COG1225	Peroxiredoxin	157
2918240905	186	99.43	6	181	2	176	2.7e-59	194.2	COG2716	Glycine cleavage system regulatory protein	176
2918240906	292	97.32	1	292	4	294	1.7e-112	369.5	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918240907	371	99.71	1	371	1	342	5.3e-76	250.4	COG3317	Uncharacterized lipoprotein	342
2918240908	252	92.31	1	233	5	256	2.5e-38	126.2	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2918240909	236	93.09	1	235	7	262	7.6e-81	265.6	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
2918240915	545	99.53	26	499	2	429	0.0e+00	490.2	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
2918240917	595	97.92	1	579	9	574	0.0e+00	597.4	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918240918	463	48.04	235	460	9	192	9.8e-32	19.4	COG0477	MFS family permease	338
2918240918	463	69.45	15	283	3	268	9.8e-32	91	COG0477	MFS family permease	338
2918240919	393	98.94	5	391	5	379	0.0e+00	528.7	COG3970	Fumarylacetoacetate (FAA) hydrolase family protein	379
2918240920	314	98.34	13	313	2	297	7.4e-54	177.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918240921	527	98.75	6	499	2	474	8.8e-77	252.9	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918240922	455	49.35	250	452	4	192	9.3e-24	11.8	COG0477	MFS family permease	338
2918240922	455	54.57	20	254	3	211	9.3e-24	72.7	COG0477	MFS family permease	338
2918240923	246	99.63	1	245	1	267	2.4e-61	202.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918240924	282	96.34	10	282	10	272	6.8e-87	285.9	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918240925	303	95.72	1	302	1	313	8.1e-82	269	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918240926	99	64.41	3	97	15	90	7.4e-11	36.9	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918240927	363	92.29	1	358	3	337	4.2e-106	349.6	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918240928	294	98.01	1	294	1	295	2.3e-47	156.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918240929	299	96.73	1	298	1	296	2.7e-93	306.8	COG3781	Predicted membrane chloride channel, bestrophin family	306
2918240930	334	99.69	7	334	2	325	1.2e-110	363.9	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
2918240931	152	96.2	1	150	6	157	1.6e-43	142.9	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918240932	389	98.24	1	387	6	395	1.3e-129	426.9	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2918240933	78	77.78	6	78	13	68	8.5e-09	30.2	COG2841	Uncharacterized conserved protein YdcH, DUF465 family	72
2918240934	121	92.13	1	118	1	117	5.0e-28	92.3	COG3232	5-carboxymethyl-2-hydroxymuconate isomerase	127
2918240935	376	99.45	8	372	1	360	3.3e-105	346.6	COG0349	Ribonuclease D	361
2918240936	97	92.23	1	95	9	103	2.7e-37	121.3	COG3100	Uncharacterized conserved protein YcgL, UPF0745 family	103
2918240937	310	93.87	1	310	21	326	2.1e-63	208.6	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918240938	197	87.04	9	192	7	194	3.6e-19	62.3	COG0778	Nitroreductase	207
2918240939	149	94.12	1	149	5	148	1.2e-66	217.7	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
2918240942	156	93.51	7	150	4	147	4.1e-21	69.6	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
2918240943	121	36.13	6	103	72	127	2.7e-04	15.1	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2918240945	155	58.26	11	154	8	134	7.4e-21	69	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918240946	677	96.19	8	677	25	681	0.0e+00	842.4	COG1770	Protease II	682
2918240947	164	32	2	147	56	175	1.3e-03	12.3	COG4585	Signal transduction histidine kinase	365
2918240948	257	98.83	1	256	1	253	3.2e-80	263.8	COG0121	Predicted glutamine amidotransferase	252
2918240950	259	94.44	10	257	5	242	4.3e-101	331.8	COG1540	Lactam utilization protein B (function unknown)	252
2918240951	227	95.59	1	223	6	222	4.3e-68	223.3	COG2049	Allophanate hydrolase subunit 1	223
2918240952	304	97.15	3	304	2	308	3.7e-94	309.7	COG1984	Allophanate hydrolase subunit 2	314
2918240953	392	99.75	1	392	1	392	0.0e+00	680.9	COG3825	Uncharacterized conserved protein,  contains von Willebrand factor type A (vWA) domain	393
2918240954	281	80.91	1	279	19	285	5.8e-66	217.2	COG0714	MoxR-like ATPase	329
2918240955	357	24.67	1	266	15	181	3.4e-07	23.2	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2918240956	324	98.68	4	311	4	301	1.2e-120	396.5	COG0031	Cysteine synthase	300
2918240958	311	97.59	11	304	6	289	1.6e-110	363.1	COG3555	Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily	291
2918240961	293	96.01	2	292	8	296	2.6e-40	133	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918240962	571	97.58	2	571	4	567	0.0e+00	854.9	COG4579	Isocitrate dehydrogenase kinase/phosphatase	578
2918240964	278	98.61	1	278	2	284	1.8e-86	284.4	COG2996	Predicted RNA-binding protein, contains S1 domains,  virulence factor B family	287
2918240967	59	86.57	1	59	1	58	1.4e-21	70.9	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2918240968	319	90.76	3	299	16	290	3.5e-81	267	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2918240969	178	90.53	1	167	2	154	8.4e-50	162.9	COG0242	Peptide deformylase	168
2918240970	149	74.69	2	117	37	157	6.9e-08	27.5	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918240972	321	91.91	1	321	10	327	2.9e-93	307.2	COG1171	Threonine dehydratase	347
2918240973	212	95.67	1	204	8	206	1.1e-25	84.5	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918240974	263	74.24	132	263	29	126	1.5e-24	80.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918240975	141	94.16	1	134	6	134	8.9e-34	111	COG4319	Ketosteroid isomerase homolog	137
2918240976	114	95.12	1	114	1	117	2.4e-39	128.7	COG3795	Uncharacterized conserved protein	123
2918240977	163	94.9	8	159	7	155	9.2e-37	120.9	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2918240978	412	98.31	5	412	4	411	0.0e+00	553.5	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
2918240979	156	91.82	1	143	13	158	3.0e-39	128.3	COG2030	Acyl dehydratase	159
2918240980	64	15.91	2	57	257	305	1.3e-07	25.4	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918240981	562	97.54	14	562	3	556	0.0e+00	483.2	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918240982	565	98.06	15	564	5	561	0.0e+00	488.7	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918240983	435	95.1	32	414	4	372	1.8e-71	235.8	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918240984	454	98.43	6	453	7	445	3.6e-123	405.9	COG0174	Glutamine synthetase	443
2918240986	1301	99.77	19	960	2	870	0.0e+00	1012.6	COG1643	HrpA-like RNA helicase	845
2918240987	373	99.08	1	373	3	325	1.1e-90	294.1	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2918240989	375	96.64	2	375	13	386	0.0e+00	504.1	COG3146	Predicted N-acyltransferase	387
2918240990	612	98.48	24	607	9	591	0.0e+00	493.3	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918240991	185	97.45	26	185	2	154	5.9e-51	167.1	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
2918240992	270	98.64	1	260	4	294	3.4e-52	172.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918240993	307	97.67	6	298	2	295	3.0e-53	175.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918240995	199	100	1	199	1	202	1.3e-73	241.1	COG1182	FMN-dependent NADH-azoreductase	202
2918240996	291	94.35	1	285	11	294	5.3e-32	105.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918240997	433	98.54	13	405	6	342	3.0e-43	142.5	COG0668	Small-conductance mechanosensitive channel	316
2918240998	453	81.15	2	451	28	449	0.0e+00	450.3	COG0513	Superfamily II DNA and RNA helicase	513
2918241001	97	93	1	96	4	96	9.3e-38	122.6	COG3636	DNA-binding prophage protein	100
2918241002	100	93	1	97	7	99	1.9e-37	122	COG3657	Putative component of the toxin-antitoxin plasmid stabilization module	100
2918241004	308	94.68	10	303	12	296	1.8e-41	136.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918241005	390	93.92	1	383	20	390	9.7e-12	38.5	COG2814	Predicted arabinose efflux permease, MFS family	394
2918241006	297	96.35	1	290	1	290	1.1e-62	206.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241008	459	94.8	1	458	4	477	3.4e-89	294.1	COG0591	Na+/proline symporter	493
2918241009	316	98.06	15	311	2	304	1.8e-89	294.2	COG0010	Arginase family enzyme	305
2918241010	297	98.01	6	296	1	295	1.4e-54	180.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241011	521	79.29	68	521	88	424	4.9e-91	300.5	COG0840	Methyl-accepting chemotaxis protein	408
2918241012	199	86.15	1	198	27	225	2.0e-56	185.5	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
2918241013	448	97.18	22	439	10	388	3.1e-39	129.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918241014	714	96.48	8	709	13	698	0.0e+00	620	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918241015	457	88.7	18	440	45	452	1.1e-61	200.4	COG1538	Outer membrane protein TolC	457
2918241016	2009	33.03	1574	1622	27	62	8.6e-04	4.3	COG3323	Uncharacterized protein	109
2918241016	2009	37.61	861	914	23	63	8.6e-04	7.1	COG3323	Uncharacterized protein	109
2918241017	120	94.96	1	119	3	115	2.4e-45	147.9	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
2918241018	195	87.56	2	195	3	192	1.6e-41	137.1	COG3318	Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C motif	216
2918241019	715	98.84	1	604	2	596	0.0e+00	772.3	COG0514	Superfamily II DNA helicase RecQ	590
2918241020	145	94.74	8	144	7	132	4.0e-21	69.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918241021	728	99.83	102	728	2	603	8.1e-83	273.5	COG0729	Outer membrane translocation and assembly module TamA	594
2918241022	93	93.94	1	93	1	93	9.8e-54	174	COG3526	Predicted selenoprotein, Rdx family	99
2918241023	296	96.35	1	290	7	296	1.5e-39	130.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918241024	254	78.79	9	251	21	124	9.1e-27	87.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918241025	103	93.33	1	103	6	103	7.8e-50	162.3	COG4323	Uncharacterized protein	105
2918241026	351	81.82	205	339	18	125	3.4e-27	88.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918241027	484	97.47	4	484	3	503	3.1e-126	416.4	COG0168	Trk-type K+ transport system, membrane component	499
2918241028	184	91.67	1	181	3	200	2.0e-21	71.1	COG0778	Nitroreductase	207
2918241029	444	80.96	99	443	71	389	1.4e-55	183.5	COG0642	Signal transduction histidine kinase	336
2918241030	138	83.12	1	138	17	149	1.5e-15	52.2	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
2918241031	225	97.41	2	225	3	228	3.2e-69	227.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918241032	116	16.67	2	84	25	95	1.2e-04	15.5	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
2918241033	99	98.91	1	98	1	91	2.7e-35	115.2	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
2918241034	198	97.78	1	193	2	177	1.2e-65	215.6	COG2917	Intracellular septation protein A	180
2918241035	286	99.22	1	265	2	257	5.4e-71	233.7	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
2918241036	209	96.23	2	208	2	205	5.7e-65	212.6	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
2918241037	275	96.37	41	275	2	240	7.1e-73	239.8	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
2918241038	261	93.48	1	183	5	176	2.4e-58	190.8	COG1386	Chromosome segregation and condensation protein ScpB	184
2918241039	367	97.97	15	260	3	243	5.0e-80	262.6	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2918241041	472	97.4	1	468	4	453	0.0e+00	612.3	COG1113	L-asparagine transporter and related permeases	462
2918241042	294	97.34	8	294	3	295	5.0e-61	201.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241043	1006	97.87	17	537	10	468	9.6e-104	341.9	COG0277	FAD/FMN-containing dehydrogenase	459
2918241043	1006	98.5	563	1005	2	396	1.2e-52	173.3	COG0247	Fe-S oxidoreductase	388
2918241044	395	49.87	215	395	11	201	2.7e-20	27.8	COG0477	MFS family permease	338
2918241044	395	69.71	6	240	6	272	2.7e-20	42.7	COG0477	MFS family permease	338
2918241046	118	95.05	14	115	3	98	8.9e-32	103.4	COG2154	Pterin-4a-carbinolamine dehydratase	101
2918241047	262	89.69	1	262	26	286	3.7e-119	391.7	COG3186	Phenylalanine-4-hydroxylase	291
2918241048	519	99.61	1	518	1	513	0.0e+00	748.7	COG3283	Transcriptional regulator of aromatic amino acids metabolism	511
2918241050	653	100	68	631	1	552	0.0e+00	804.3	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918241051	261	96.47	1	261	6	278	5.0e-65	214.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918241052	229	98.7	1	227	2	228	1.2e-92	303.8	COG4215	ABC-type arginine transport system, permease component	230
2918241053	232	98.25	3	229	2	225	5.2e-94	308.4	COG4160	ABC-type arginine/histidine transport system, permease component	228
2918241054	254	98.05	1	254	5	255	0.0e+00	464.4	COG4598	ABC-type histidine transport system, ATPase component	256
2918241055	326	97.23	1	315	7	322	4.5e-98	322.6	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918241056	402	96.54	2	402	10	400	0.0e+00	541.5	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2918241057	339	99.7	1	339	1	335	0.0e+00	456.4	COG3138	Arginine/ornithine N-succinyltransferase beta subunit	336
2918241058	341	99.4	1	335	2	335	0.0e+00	483.1	COG3138	Arginine/ornithine N-succinyltransferase beta subunit	336
2918241059	487	97.08	2	474	2	466	7.2e-130	427.9	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918241060	449	100	1	448	1	442	0.0e+00	754.2	COG3724	Succinylarginine dihydrolase	442
2918241062	335	97.84	4	330	2	318	2.6e-112	369.3	COG2988	Succinylglutamate desuccinylase	324
2918241063	874	98.53	1	873	6	874	0.0e+00	1166.7	COG0013	Alanyl-tRNA synthetase	879
2918241064	411	99.77	1	404	1	442	0.0e+00	489.8	COG0527	Aspartokinase	447
2918241065	62	79.45	1	62	1	58	4.1e-29	95.1	COG1551	sRNA-binding carbon storage regulator CsrA	73
2918241070	480	97.58	35	480	9	451	0.0e+00	536.6	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
2918241071	108	70	14	92	6	61	3.8e-04	15.1	COG4691	Plasmid stability protein	80
2918241072	201	93.75	10	196	4	183	1.3e-65	214.7	COG3709	Ribose 1,5-bisphosphokinase PhnN	192
2918241078	102	44.28	8	102	6	94	7.3e-15	49.4	COG4723	Phage-related protein, tail component	198
2918241081	166	17.77	13	162	283	357	1.8e-04	15	COG4653	Predicted phage phi-C31 gp36 major capsid-like protein	422
2918241083	237	27.67	62	227	154	223	1.9e-16	54.3	COG1637	Endonuclease NucS, RecB family	253
2918241085	457	96.21	18	426	14	343	1.5e-80	265.2	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918241086	459	99.34	3	449	4	455	0.0e+00	478	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918241087	423	99.31	2	423	3	433	0.0e+00	437	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2918241088	352	99.69	18	352	1	323	0.0e+00	473.8	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
2918241089	410	98.88	52	410	3	356	4.9e-113	371.9	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
2918241090	161	98.1	1	153	3	157	9.1e-42	137.2	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918241091	447	96.64	2	446	13	443	1.5e-120	397.2	COG0174	Glutamine synthetase	443
2918241092	443	48.04	192	404	9	192	1.3e-27	49.3	COG0477	MFS family permease	338
2918241092	443	49.87	1	201	1	191	1.3e-27	48.9	COG0477	MFS family permease	338
2918241094	247	97.42	4	246	6	232	1.3e-48	159.8	COG5581	c-di-GMP-binding flagellar brake protein YcgR, contains PilZNR and PilZ domains	233
2918241095	155	92.47	3	155	4	138	5.4e-22	72.8	COG3418	Flagellar biosynthesis/type III secretory pathway chaperone	146
2918241096	104	90.32	3	104	10	93	4.6e-21	69.8	COG2747	Negative regulator of flagellin synthesis (anti-sigma28 factor)	93
2918241097	250	94.55	21	250	13	220	1.9e-47	156.2	COG1261	Flagella basal body P-ring formation protein FlgA	220
2918241098	309	88.72	175	308	6	123	1.2e-22	73.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918241098	309	96.36	3	167	3	161	1.3e-47	155.4	COG0835	Chemotaxis signal transduction protein	165
2918241099	275	98.15	5	275	3	267	4.1e-87	286.2	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918241100	135	98.52	2	135	2	134	5.1e-45	147.6	COG1815	Flagellar basal body rod protein FlgB	133
2918241101	147	100	1	147	1	138	4.5e-54	176.8	COG1558	Flagellar basal body rod protein FlgC	137
2918241102	233	96.86	9	232	7	222	1.6e-57	189	COG1843	Flagellar hook assembly protein FlgD	222
2918241103	587	61.23	297	587	182	470	3.8e-108	182.8	COG1749	Flagellar hook protein FlgE	423
2918241103	587	63.77	1	314	3	303	3.8e-108	180	COG1749	Flagellar hook protein FlgE	423
2918241105	246	99.2	1	246	2	250	1.4e-96	317.5	COG4787	Flagellar basal body rod protein FlgF	251
2918241106	261	99.25	1	261	1	263	5.2e-98	322.2	COG4786	Flagellar basal body rod protein FlgG	265
2918241107	231	97.4	1	228	4	228	2.6e-68	224.6	COG2063	Flagellar basal body L-ring protein FlgH	230
2918241108	369	98.63	1	369	6	365	0.0e+00	506.6	COG1706	Flagellar basal body P-ring protein FlgI	365
2918241109	398	95	30	397	2	267	2.6e-66	218.1	COG1705	Flagellum-specific peptidoglycan hydrolase FlgJ	201
2918241110	677	99.32	1	677	3	586	7.2e-120	395.8	COG1256	Flagellar hook-associated protein FlgK	552
2918241111	525	98.97	1	525	2	385	1.9e-42	138.9	COG1344	Flagellin and related hook-associated protein FlgL	360
2918241112	1197	31.2	399	551	77	188	2.6e-21	14.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918241112	1197	40.11	15	173	2	145	2.6e-21	53	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918241114	460	54.84	208	451	42	194	3.2e-07	24.4	COG0500	SAM-dependent methyltransferase	257
2918241115	311	97.85	1	309	5	323	2.6e-61	201.4	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2918241116	290	31.19	157	290	267	387	6.1e-88	103.6	COG1344	Flagellin and related hook-associated protein FlgL	360
2918241116	290	43.04	3	181	2	168	6.1e-88	189.4	COG1344	Flagellin and related hook-associated protein FlgL	360
2918241117	116	85	1	116	19	120	6.1e-26	85.7	COG1334	Uncharacterized conserved protein, FlaG/YvyC family	120
2918241118	465	98.59	1	461	6	496	3.4e-60	198.7	COG1345	Flagellar capping protein FliD	483
2918241119	131	90.91	1	130	4	123	9.8e-37	120.2	COG1516	Flagellin-specific chaperone FliS	132
2918241121	491	98.93	1	488	2	463	0.0e+00	514.2	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918241122	398	82.99	26	394	62	388	2.1e-44	146.6	COG0642	Signal transduction histidine kinase	336
2918241123	453	97.43	1	449	5	459	0.0e+00	545.5	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918241124	110	96.23	1	110	5	106	2.5e-32	105.9	COG1677	Flagellar hook-basal body complex protein FliE	105
2918241125	592	97.81	22	591	13	548	0.0e+00	578.9	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
2918241126	339	98.53	1	339	6	340	1.9e-121	400	COG1536	Flagellar motor switch protein FliG	339
2918241127	253	92.59	2	237	13	237	7.5e-47	154.3	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
2918241128	452	96.15	9	448	16	440	0.0e+00	614.6	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
2918241129	150	93.24	3	148	4	141	2.4e-34	112.8	COG2882	Flagellar biosynthesis chaperone FliJ	148
2918241130	101	77.78	3	101	13	103	4.0e-17	56.5	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918241131	563	85.71	2	389	4	117	7.7e-31	97.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918241132	130	71.2	8	128	24	112	2.2e-15	51.5	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918241133	420	85.62	3	420	64	438	3.9e-29	94.4	COG3144	Flagellar hook-length control protein FliK	417
2918241134	165	98.11	1	165	4	159	2.0e-30	100.1	COG1580	Flagellar basal body-associated protein FliL	159
2918241135	322	96.4	1	322	2	322	1.2e-113	374	COG1868	Flagellar motor switch protein FliM	332
2918241136	152	98.58	3	141	3	141	1.5e-37	123.7	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
2918241137	149	92.14	22	149	11	139	5.2e-27	88.8	COG3190	Flagellar biogenesis protein FliO	137
2918241138	251	98.39	1	249	4	248	2.5e-103	339.2	COG1338	Flagellar biosynthetic protein FliP	248
2918241139	89	98.88	1	89	1	88	2.8e-32	105.2	COG1987	Flagellar biosynthesis protein FliQ	89
2918241140	258	98.06	2	257	2	254	1.4e-74	245.1	COG1684	Flagellar biosynthesis protein FliR	258
2918241141	381	98.9	2	366	3	361	2.8e-127	419.1	COG1377	Flagellar biosynthesis protein FlhB	363
2918241142	709	98.85	3	708	7	695	0.0e+00	924	COG1298	Flagellar biosynthesis pathway, component FlhA	696
2918241143	436	99.52	1	420	1	412	5.0e-106	349.5	COG1419	Flagellar biosynthesis GTPase FlhF	407
2918241144	274	96.99	3	267	3	260	5.9e-75	246.6	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
2918241145	246	93.25	3	243	17	251	2.5e-77	254.2	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
2918241146	124	91.73	1	123	7	128	2.0e-31	103	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918241147	262	99.08	30	262	3	217	6.2e-77	252.5	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2918241148	741	98.41	2	740	5	746	0.0e+00	710.1	COG0643	Chemotaxis protein histidine kinase CheA	716
2918241149	379	97.44	2	379	2	344	0.0e+00	435.3	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918241150	246	92.51	1	246	1	247	4.1e-80	263	COG1291	Flagellar motor component MotA	266
2918241151	285	98.52	1	247	3	268	2.3e-57	189.1	COG1360	Flagellar motor protein MotB	244
2918241152	262	96.97	1	259	2	257	8.3e-66	216.9	COG1192	Cellulose biosynthesis protein BcsQ	259
2918241153	299	81.82	145	296	18	152	2.7e-08	27	COG0835	Chemotaxis signal transduction protein	165
2918241154	159	93.33	1	159	8	161	6.6e-52	169.9	COG0835	Chemotaxis signal transduction protein	165
2918241158	114	96.74	1	88	1	89	2.4e-30	99	COG2257	Type III secretion system substrate exporter, FlhB-like	92
2918241160	210	97.13	3	210	2	204	2.9e-82	269.8	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
2918241161	222	99.55	1	221	1	220	1.7e-81	267.5	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
2918241162	255	85.11	1	250	37	276	7.7e-69	226.7	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
2918241163	58	85.07	1	58	1	57	2.4e-24	79.9	COG3114	Heme exporter protein D	67
2918241164	152	94.77	1	152	2	146	3.0e-59	193.4	COG2332	Cytochrome c-type biogenesis protein CcmE	153
2918241165	662	99.23	6	653	1	641	0.0e+00	853.5	COG1138	Cytochrome c biogenesis factor	648
2918241166	178	96	9	157	3	146	5.0e-13	43.2	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2918241167	158	96.73	1	154	5	152	5.3e-55	179.2	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
2918241168	395	97.92	2	281	2	284	2.9e-66	217.8	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
2918241170	312	88.69	6	312	36	325	1.6e-83	274.5	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918241171	135	96.3	1	130	2	131	2.6e-31	102.7	COG3791	Uncharacterized conserved protein	133
2918241172	112	50.97	1	108	101	205	2.3e-48	159.3	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
2918241174	242	100	1	228	1	230	4.2e-59	194	COG4126	Asp/Glu/hydantoin racemase	230
2918241175	510	93.43	7	504	22	490	0.0e+00	515	COG1953	Cytosine/uracil/thiamine/allantoin permease	497
2918241177	145	87.34	1	143	6	143	1.6e-31	103.8	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918241178	301	95.02	5	290	8	293	3.8e-40	132.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918241179	309	72.77	3	304	89	374	4.5e-65	214.2	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
2918241180	676	91.23	165	672	6	317	6.5e-43	135.2	COG0668	Small-conductance mechanosensitive channel	316
2918241181	332	90.26	2	332	31	345	0.0e+00	497.5	COG1613	ABC-type sulfate transport system, periplasmic component	348
2918241182	274	64.57	12	248	46	189	2.0e-11	38.2	COG1226	Voltage-gated potassium channel Kch	212
2918241183	292	89.34	12	285	12	296	1.2e-46	148.1	COG4413	Urea transporter	319
2918241184	471	99.16	1	470	4	477	0.0e+00	566.7	COG0469	Pyruvate kinase	477
2918241185	424	99.05	1	419	4	421	0.0e+00	572.2	COG2379	Glycerate-2-kinase	422
2918241186	297	99.65	2	286	2	286	2.6e-114	375.6	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918241187	260	99.23	1	260	1	258	2.3e-122	401.9	COG3622	Hydroxypyruvate isomerase	260
2918241188	591	99.66	1	591	1	590	0.0e+00	1198.4	COG3960	Glyoxylate carboligase	592
2918241189	146	95.74	1	140	5	139	6.1e-41	134.2	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2918241190	203	93.78	1	201	8	203	5.3e-32	106.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918241191	304	99.01	1	298	1	300	4.2e-124	407.9	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
2918241192	260	87.32	1	260	37	284	3.4e-72	237.1	COG3248	Nucleoside-specific outer membrane channel protein Tsx	284
2918241193	261	87.32	8	261	37	284	4.6e-65	214.2	COG3248	Nucleoside-specific outer membrane channel protein Tsx	284
2918241194	451	95.39	2	450	9	443	0.0e+00	493.7	COG2233	Xanthine/uracil permease	451
2918241195	439	99.26	1	439	2	406	0.0e+00	556.5	COG3748	Uncharacterized membrane protein	407
2918241196	167	95.24	1	166	1	160	1.7e-69	226.9	COG3194	Ureidoglycolate hydrolase (allantoin degradation)	168
2918241197	171	94.89	1	171	4	170	5.9e-70	229.2	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
2918241198	308	95.15	4	301	11	265	1.1e-56	186.4	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918241199	117	94.35	1	117	8	124	2.2e-52	170.7	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
2918241202	398	82.26	1	263	57	325	1.2e-67	222.4	COG3344	Retron-type reverse transcriptase	328
2918241204	449	99.1	18	449	3	441	0.0e+00	570.7	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
2918241205	252	92.67	9	235	12	226	6.9e-63	206.3	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918241206	434	97.64	3	434	4	417	8.5e-125	410.9	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918241207	281	96.35	2	270	2	291	2.9e-74	244.4	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2918241208	799	99.49	7	787	3	779	0.0e+00	1315	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
2918241209	484	97.57	1	484	9	489	0.0e+00	709.3	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
2918241210	219	93.1	1	219	11	226	2.3e-40	132.8	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918241211	1162	99.91	1	1160	1	1167	0.0e+00	946.1	COG1196	Chromosome segregation ATPase	1163
2918241212	296	99.38	2	292	2	323	1.9e-77	249.8	COG3115	Cell division protein ZipA, interacts with FtsZ	324
2918241213	776	24.48	600	770	508	672	0.0e+00	127.8	COG0272	NAD-dependent DNA ligase	667
2918241213	776	86.8	1	607	6	590	0.0e+00	843.7	COG0272	NAD-dependent DNA ligase	667
2918241216	481	11.16	25	108	36	61	2.2e-11	10	COG3910	Predicted ATPase	233
2918241216	481	27.47	198	296	142	205	2.2e-11	26.1	COG3910	Predicted ATPase	233
2918241218	203	40.71	2	180	60	151	7.6e-09	22.9	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2918241219	55	17.2	1	52	143	185	2.7e-13	44.5	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
2918241227	186	90.27	1	186	1	204	4.9e-45	148.3	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2918241231	76	47.69	13	76	2	63	2.9e-17	57.3	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918241234	284	58.68	7	138	12	109	1.2e-10	34.9	COG3646	Phage regulatory protein Rha	167
2918241234	284	61.48	147	267	21	103	2.9e-12	40.4	COG3645	Phage antirepressor protein YoqD, KilAC domain	135
2918241235	150	91.11	11	147	7	129	1.8e-19	64	COG3645	Phage antirepressor protein YoqD, KilAC domain	135
2918241236	434	72.24	106	431	75	316	7.0e-21	69.1	COG0582	Integrase	309
2918241239	135	78.79	1	128	1	104	1.1e-18	62	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918241240	165	30.3	9	159	272	394	7.3e-02	6.3	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2918241241	299	95.68	1	287	6	293	1.1e-37	124.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918241242	683	11.79	522	680	464	532	0.0e+00	1.5	COG2812	DNA polymerase III, gamma/tau subunits	515
2918241242	683	69.57	1	504	1	407	0.0e+00	541.6	COG2812	DNA polymerase III, gamma/tau subunits	515
2918241243	108	98.1	1	105	3	105	5.1e-42	136.6	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
2918241244	200	99.49	1	198	2	198	4.9e-77	252.1	COG0353	Recombinational DNA repair protein RecR	198
2918241245	182	95.53	1	178	7	177	6.1e-51	166.6	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
2918241246	244	99.08	13	232	2	217	1.7e-42	139.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918241247	460	99.05	13	451	3	418	0.0e+00	437.2	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
2918241248	227	97.46	2	227	4	233	5.9e-71	233	COG2836	Sulfite exporter TauE/SafE	232
2918241249	70	84.48	1	70	1	49	3.2e-26	85.4	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
2918241250	821	99.04	92	802	4	727	0.0e+00	722.8	COG2217	Cation transport ATPase	713
2918241251	174	96.51	5	174	3	168	8.2e-55	179.2	COG3198	Uncharacterized protein	172
2918241252	471	97.98	32	448	3	391	4.0e-127	418.5	COG0348	Polyferredoxin	386
2918241253	327	51.83	226	327	61	145	1.5e-45	44.6	COG2010	Cytochrome c, mono- and diheme variants	150
2918241253	327	84.76	72	234	7	145	1.5e-45	107.7	COG2010	Cytochrome c, mono- and diheme variants	150
2918241254	68	83.33	3	65	5	54	4.4e-13	43.4	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
2918241255	202	96.93	1	202	3	223	3.2e-100	324	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
2918241256	480	96.49	1	477	10	476	0.0e+00	820.6	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
2918241258	313	53.66	211	313	58	145	9.3e-44	46.5	COG2010	Cytochrome c, mono- and diheme variants	150
2918241258	313	85.37	72	221	6	145	9.3e-44	101.9	COG2010	Cytochrome c, mono- and diheme variants	150
2918241259	65	85	1	57	1	51	8.2e-10	33.1	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
2918241260	202	97.37	1	202	3	224	1.6e-102	331.1	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
2918241261	474	96.28	1	474	9	474	0.0e+00	825.2	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
2918241262	176	83.57	1	176	32	209	1.3e-71	234.9	COG3571	Predicted hydrolase of the alpha/beta-hydrolase fold	213
2918241263	94	100	1	93	1	94	1.8e-45	147.6	COG3123	Uncharacterized conserved protein YaiE, UPF0345 family	94
2918241264	183	85.71	1	182	3	182	5.9e-66	216.3	COG5018	Inhibitor of the KinA pathway to sporulation, predicted exonuclease	210
2918241265	257	87.63	1	255	25	272	6.8e-10	32.9	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918241266	337	79.68	155	334	18	166	2.8e-09	28.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918241267	176	87.1	3	175	15	176	1.2e-33	110.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918241269	4317	11.62	1813	1884	110	160	1.7e-18	7.6	COG4908	Uncharacterized protein, contains a NRPS condensation (elongation) domain	439
2918241269	4317	28.47	699	839	34	158	1.7e-18	19.4	COG4908	Uncharacterized protein, contains a NRPS condensation (elongation) domain	439
2918241269	4317	31.02	2995	3345	3	203	0.0e+00	17.9	COG1020	Non-ribosomal peptide synthetase component F	642
2918241269	4317	49.89	2790	3035	32	250	1.7e-18	29	COG4908	Uncharacterized protein, contains a NRPS condensation (elongation) domain	439
2918241269	4317	62.35	2	472	232	635	0.0e+00	101.7	COG1020	Non-ribosomal peptide synthetase component F	642
2918241269	4317	71.6	583	656	9	66	7.2e-12	5.9	COG0236	Acyl carrier protein	80
2918241269	4317	77.78	4222	4296	17	79	7.2e-12	15.9	COG0236	Acyl carrier protein	80
2918241269	4317	91.36	1624	1700	3	76	7.2e-12	6.2	COG0236	Acyl carrier protein	80
2918241269	4317	91.36	2696	2771	5	78	7.2e-12	5.8	COG0236	Acyl carrier protein	80
2918241269	4317	98.77	3469	4131	8	647	0.0e+00	437.4	COG1020	Non-ribosomal peptide synthetase component F	642
2918241269	4317	98.92	897	1545	6	646	0.0e+00	534.4	COG1020	Non-ribosomal peptide synthetase component F	642
2918241269	4317	99.85	1946	2603	1	647	0.0e+00	506.3	COG1020	Non-ribosomal peptide synthetase component F	642
2918241270	4751	14.35	3444	3676	3	95	0.0e+00	17.3	COG1020	Non-ribosomal peptide synthetase component F	642
2918241270	4751	85.19	4657	4744	4	72	2.1e-12	7.3	COG0236	Acyl carrier protein	80
2918241270	4751	86.42	2072	2145	7	76	2.1e-12	13.9	COG0236	Acyl carrier protein	80
2918241270	4751	87.65	3137	3208	4	74	2.1e-12	13	COG0236	Acyl carrier protein	80
2918241270	4751	99.38	1318	1982	4	647	0.0e+00	495.9	COG1020	Non-ribosomal peptide synthetase component F	642
2918241270	4751	99.38	2388	3044	5	648	0.0e+00	500.8	COG1020	Non-ribosomal peptide synthetase component F	642
2918241270	4751	99.69	3909	4570	2	647	0.0e+00	561.2	COG1020	Non-ribosomal peptide synthetase component F	642
2918241270	4751	99.85	277	915	2	648	0.0e+00	407.2	COG1020	Non-ribosomal peptide synthetase component F	642
2918241271	1126	79.01	1022	1097	4	67	2.6e-03	11.4	COG0236	Acyl carrier protein	80
2918241271	1126	99.07	276	929	7	648	0.0e+00	625.4	COG1020	Non-ribosomal peptide synthetase component F	642
2918241272	2633	12.81	1326	1548	7	89	0.0e+00	6.2	COG1020	Non-ribosomal peptide synthetase component F	642
2918241272	2633	79.73	1019	1090	3	61	1.3e-04	13.4	COG3433	Aryl carrier domain	74
2918241272	2633	99.07	271	924	7	648	0.0e+00	604.7	COG1020	Non-ribosomal peptide synthetase component F	642
2918241272	2633	99.38	1792	2443	5	648	0.0e+00	520.4	COG1020	Non-ribosomal peptide synthetase component F	642
2918241273	4109	13.12	1331	1652	7	91	0.0e+00	14.3	COG1020	Non-ribosomal peptide synthetase component F	642
2918241273	4109	14.81	3892	4030	5	100	0.0e+00	10.8	COG1020	Non-ribosomal peptide synthetase component F	642
2918241273	4109	62.16	1023	1093	15	60	5.4e-09	8.9	COG3433	Aryl carrier domain	74
2918241273	4109	85.14	2534	2604	9	71	5.4e-09	11.7	COG3433	Aryl carrier domain	74
2918241273	4109	98.77	2847	3500	8	647	0.0e+00	395.1	COG1020	Non-ribosomal peptide synthetase component F	642
2918241273	4109	99.07	277	934	6	647	0.0e+00	601.9	COG1020	Non-ribosomal peptide synthetase component F	642
2918241273	4109	99.23	1794	2443	6	648	0.0e+00	543.5	COG1020	Non-ribosomal peptide synthetase component F	642
2918241274	318	78.3	7	316	52	300	5.3e-66	217.6	COG0657	Acetyl esterase/lipase	312
2918241275	808	94.03	91	808	43	719	0.0e+00	681.5	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
2918241276	549	96.34	9	548	4	529	0.0e+00	664.2	COG4615	ABC-type siderophore export system, fused ATPase and permease components	546
2918241277	83	4.59	2	25	3	22	3.3e-14	20.3	COG3486	Lysine/ornithine N-monooxygenase	436
2918241277	83	11.93	23	82	374	425	3.3e-14	25.2	COG3486	Lysine/ornithine N-monooxygenase	436
2918241279	364	96.95	12	364	9	358	4.7e-77	253.5	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2918241280	291	81.98	6	286	60	332	7.0e-72	236.8	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918241281	442	99.06	38	426	3	317	1.3e-89	294.7	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
2918241283	470	98.04	11	469	2	452	3.0e-111	366.8	COG1538	Outer membrane protein TolC	457
2918241284	655	97.35	5	231	2	221	3.2e-84	275.6	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918241284	655	99.8	279	655	2	510	8.2e-76	250.4	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918241285	393	88.21	3	389	25	368	6.1e-56	184.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918241286	166	86.02	2	166	20	179	1.4e-38	126.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918241287	121	76.82	1	117	35	150	4.7e-48	157.5	COG3241	Azurin	151
2918241289	441	49.87	243	437	8	198	3.1e-33	11	COG0477	MFS family permease	338
2918241289	441	61.1	16	267	3	236	3.1e-33	103.3	COG0477	MFS family permease	338
2918241292	554	99.75	5	467	2	407	5.1e-119	392.1	COG0644	Dehydrogenase (flavoprotein)	396
2918241293	249	99.62	1	249	1	260	3.4e-89	292.8	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2918241294	309	98.43	1	309	1	313	2.4e-110	363.5	COG2025	Electron transfer flavoprotein, alpha subunit	313
2918241295	273	95.05	1	272	8	276	1.4e-16	53.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918241297	269	78.89	57	261	41	197	4.4e-43	142.1	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918241298	480	98.46	2	474	5	453	0.0e+00	442.5	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918241300	84	47.18	1	73	11	77	1.5e-04	15.7	COG0727	Fe-S-cluster containining protein	132
2918241302	663	82.3	1	609	1	451	1.0e-112	371.3	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2918241303	332	71.54	6	310	28	296	3.3e-41	135.9	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918241304	82	75.31	2	77	20	80	7.8e-05	17.1	COG0236	Acyl carrier protein	80
2918241305	255	28.14	88	250	193	275	7.3e-08	13.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918241305	255	37.29	10	185	23	132	7.3e-08	16.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918241306	100	88.89	5	93	5	76	1.2e-13	45.3	COG0236	Acyl carrier protein	80
2918241307	150	79.05	5	128	20	136	3.4e-29	95.6	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2918241308	327	10.14	259	310	326	367	1.4e-19	2.9	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918241308	327	31.88	2	200	62	193	1.4e-19	59.8	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918241309	330	94.39	26	135	4	104	6.1e-16	52.1	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2918241310	103	95.05	1	99	4	99	1.4e-18	61.4	COG1605	Chorismate mutase	101
2918241311	473	89.41	21	464	44	423	7.9e-106	349.1	COG1169	Isochorismate synthase EntC	423
2918241312	282	94.64	3	282	13	277	5.6e-61	200.7	COG3687	Predicted metal-dependent hydrolase	280
2918241313	596	64.04	2	433	234	648	6.6e-82	270.2	COG1020	Non-ribosomal peptide synthetase component F	642
2918241314	396	99.28	1	391	2	412	1.3e-96	318	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918241316	525	95.57	3	525	16	533	0.0e+00	554.5	COG1021	Non-ribosomal peptide synthetase component E (peptide arylation enzyme)	542
2918241317	429	97.73	27	428	10	396	0.0e+00	543.8	COG0372	Citrate synthase	390
2918241318	128	95.49	7	128	2	128	2.5e-28	93.3	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
2918241319	122	98.29	1	122	2	116	1.4e-35	116	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
2918241320	570	95.58	1	561	20	560	0.0e+00	722.9	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918241321	234	97.45	1	234	3	231	4.6e-89	291.8	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
2918241323	943	99.89	6	943	1	922	0.0e+00	1375.5	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
2918241324	408	99.77	1	407	1	433	0.0e+00	514.8	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2918241325	478	100	1	462	1	455	0.0e+00	537.5	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918241327	388	99.74	1	388	1	382	0.0e+00	549.8	COG0045	Succinyl-CoA synthetase, beta subunit	387
2918241328	294	98.3	1	291	1	289	0.0e+00	443.3	COG0074	Succinyl-CoA synthetase, alpha subunit	293
2918241329	423	96.75	1	417	13	429	0.0e+00	518.1	COG1114	Branched-chain amino acid permeases	431
2918241330	254	96.58	5	239	4	229	8.8e-97	317.4	COG3821	Uncharacterized membrane protein	234
2918241331	91	33.54	6	82	44	97	2.4e-02	8.5	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2918241332	159	89.36	1	143	14	139	4.8e-26	85.5	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918241333	152	85.82	9	150	16	136	2.6e-18	60.4	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918241334	635	99.36	4	635	2	623	0.0e+00	887.1	COG0326	Molecular chaperone, HSP90 family	623
2918241335	241	95.36	7	241	10	235	1.8e-47	156	COG0412	Dienelactone hydrolase	236
2918241336	334	50.33	112	333	148	300	5.7e-10	32.7	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2918241337	406	99.52	1	404	2	413	0.0e+00	458.5	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918241338	171	97.3	12	167	3	146	1.0e-41	136.5	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2918241339	504	93.15	21	497	24	390	1.1e-78	259.3	COG0642	Signal transduction histidine kinase	336
2918241341	715	89.94	3	709	39	753	3.3e-43	142.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918241342	341	99.39	4	331	2	328	8.3e-118	387.6	COG0240	Glycerol-3-phosphate dehydrogenase	329
2918241344	152	95.71	1	152	3	158	5.1e-34	111.7	COG2062	Phosphohistidine phosphatase SixA	163
2918241345	262	90.51	2	259	25	291	5.6e-16	53.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918241346	284	96.27	7	282	5	288	8.7e-29	95.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918241348	350	92.5	1	349	15	347	3.1e-73	241.1	COG0628	Predicted PurR-regulated permease PerM	355
2918241350	564	98.57	3	562	8	559	0.0e+00	796.8	COG2060	K+-transporting ATPase, A chain	560
2918241351	684	98.39	12	684	10	680	0.0e+00	1060.9	COG2216	High-affinity K+ transport system, ATPase chain B	681
2918241352	182	98.94	1	181	1	187	7.3e-63	206.1	COG2156	K+-transporting ATPase, c chain	190
2918241353	884	99.22	1	884	5	894	0.0e+00	1015.2	COG2205	K+-sensing histidine kinase KdpD	890
2918241354	232	97.84	5	230	3	229	3.4e-74	243.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918241356	536	99.25	1	532	2	531	0.0e+00	855.4	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
2918241357	339	98.83	1	339	3	339	0.0e+00	580	COG4239	ABC-type microcin C transport system, permease component YejE	341
2918241358	357	99.73	1	356	1	363	0.0e+00	622.9	COG4174	ABC-type microcin C transport system, permease component YejB	364
2918241359	613	97.74	4	599	11	571	0.0e+00	510.8	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2918241360	609	98.61	1	608	8	573	0.0e+00	524.6	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2918241361	476	32.65	411	474	85	132	8.8e-23	40.8	COG1388	LysM repeat	124
2918241361	476	61.22	204	419	45	134	8.8e-23	31.7	COG1388	LysM repeat	124
2918241362	259	92.31	1	228	19	258	2.4e-43	142.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918241363	258	21.86	7	248	120	180	4.7e-05	18.3	COG0500	SAM-dependent methyltransferase	257
2918241364	148	94.23	2	148	2	148	8.0e-63	205.4	COG0328	Ribonuclease HI	154
2918241365	247	91.73	1	245	15	247	1.0e-58	193.4	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2918241366	753	99.49	140	751	3	592	0.0e+00	736.5	COG1982	Arginine/lysine/ornithine decarboxylase	557
2918241368	186	94.57	5	185	3	176	1.3e-47	156.2	COG0431	NAD(P)H-dependent FMN reductase	184
2918241369	275	98.19	9	267	3	219	9.6e-48	156.9	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2918241370	368	94.26	1	368	6	366	2.2e-108	356.9	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
2918241371	287	96.01	1	286	1	289	3.0e-55	182.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241372	340	90.15	203	336	7	125	1.4e-20	67	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918241374	548	97.46	25	544	7	544	0.0e+00	513.5	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918241375	255	99.25	1	251	1	266	1.2e-52	173.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918241376	397	99.24	5	396	2	392	8.8e-127	417.7	COG0183	Acetyl-CoA acetyltransferase	392
2918241377	375	96.99	1	375	6	392	0.0e+00	468.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918241378	257	99.25	1	254	3	265	2.3e-85	280.5	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918241380	134	98.33	15	133	1	118	3.3e-29	96.1	COG1734	RNA polymerase-binding transcription factor DksA	120
2918241385	121	86.73	8	117	2	99	7.5e-24	78.3	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
2918241386	92	94.38	4	91	6	89	1.7e-26	86.7	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
2918241387	162	98.1	4	162	4	158	3.6e-36	118.9	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
2918241388	558	99.21	4	544	1	502	4.6e-121	398.7	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
2918241389	114	98.25	1	114	1	112	4.2e-36	117.6	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
2918241390	976	94	3	648	2	581	0.0e+00	564.8	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2918241391	315	95.35	15	300	10	296	4.3e-32	105.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918241392	187	63.08	14	140	3	84	2.0e-14	48.7	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918241393	156	94.7	13	130	2	126	6.8e-25	82.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918241395	256	27.12	134	238	212	291	1.3e-15	10.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918241395	256	44.75	6	175	13	144	1.3e-15	43	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918241397	602	96.67	172	561	11	387	1.1e-83	274.6	COG0006	Xaa-Pro aminopeptidase	384
2918241399	295	97.6	1	291	4	288	2.9e-121	398.1	COG5006	Threonine/homoserine efflux transporter RhtA	292
2918241403	287	82.39	133	276	28	158	1.1e-16	35	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918241403	287	97.48	1	128	4	158	1.1e-16	20.2	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918241404	205	98.03	1	201	4	202	1.8e-87	286.6	COG4445	tRNA isopentenyl-2-thiomethyl-A-37 hydroxylase MiaE (synthesis of 2-methylthio-cis-ribozeatin)	203
2918241405	106	97.12	5	105	4	104	1.4e-27	90.7	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2918241407	159	59.01	4	120	14	108	1.1e-04	16.1	COG5608	LEA14-like dessication related protein	161
2918241409	383	87.65	4	382	48	409	1.4e-116	384	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2918241410	366	95.7	1	366	11	366	1.3e-119	391.6	COG1485	Predicted ATPase	367
2918241411	332	94.92	21	332	14	293	4.1e-41	135.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918241412	145	85.71	1	144	18	155	2.5e-51	168	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
2918241413	161	91.95	17	161	10	146	3.6e-52	170.3	COG3019	Uncharacterized conserved protein	149
2918241414	353	92.78	1	353	14	347	1.7e-67	222.3	COG0628	Predicted PurR-regulated permease PerM	355
2918241415	686	92.2	3	685	63	795	5.0e-29	89	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918241416	81	77.5	7	79	17	78	4.3e-21	68.6	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918241421	489	98.53	4	488	3	471	0.0e+00	498.5	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
2918241422	510	98.19	1	510	4	492	0.0e+00	619.6	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
2918241423	617	99.51	4	611	2	615	0.0e+00	629.7	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2918241424	102	99	3	102	2	100	9.4e-39	125.8	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
2918241425	166	97.62	1	164	4	167	3.7e-49	160.9	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
2918241426	182	88.57	3	176	15	169	6.0e-55	179.6	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
2918241427	335	99.1	1	329	1	330	0.0e+00	442.3	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
2918241428	904	99.86	1	779	1	730	0.0e+00	798.6	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
2918241429	459	97.64	10	437	7	420	0.0e+00	613.8	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2918241430	165	95.78	2	165	5	163	2.2e-62	203.6	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2918241431	593	96.11	14	196	5	177	3.0e-55	180.9	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
2918241431	593	99.75	196	593	2	398	0.0e+00	564.8	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
2918241432	225	96.39	17	215	5	191	1.5e-80	263.1	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
2918241433	137	95.9	4	125	5	121	3.3e-43	140.9	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
2918241435	441	38.98	256	440	289	472	0.0e+00	269.9	COG2224	Isocitrate lyase	433
2918241435	441	54.87	2	265	4	262	0.0e+00	376	COG2224	Isocitrate lyase	433
2918241436	254	5.68	18	97	306	340	5.9e-12	21.2	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
2918241436	254	18.18	126	232	424	535	5.9e-12	20.2	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
2918241437	571	33.51	91	519	263	452	9.2e-12	35.2	COG1404	Serine protease, subtilisin family	508
2918241438	480	92.01	1	480	19	536	2.2e-122	403.4	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2918241439	702	99.31	1	702	1	724	0.0e+00	953.3	COG0480	Translation elongation factor EF-G, a GTPase	697
2918241442	416	93.95	1	416	26	444	5.0e-130	428.5	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2918241443	298	97.67	7	298	4	297	3.8e-67	221.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241444	468	96.75	2	460	4	450	0.0e+00	507.5	COG1113	L-asparagine transporter and related permeases	462
2918241446	231	96.28	21	231	3	209	2.4e-53	175.4	COG0625	Glutathione S-transferase	211
2918241447	143	79.01	3	132	26	153	2.8e-12	41.4	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918241448	129	63.85	3	123	2	84	7.4e-13	43.9	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918241449	212	99.53	2	209	1	210	9.6e-63	205.9	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918241450	607	99.5	3	604	3	597	0.0e+00	746.5	COG0322	Excinuclease UvrABC, nuclease subunit	581
2918241451	186	93.81	1	183	12	193	1.9e-54	179.1	COG0558	Phosphatidylglycerophosphate synthase	192
2918241453	601	97.01	83	407	7	331	2.4e-33	110.5	COG0582	Integrase	309
2918241455	203	91.98	3	163	11	159	3.3e-24	79.4	COG3236	Predicted NAD-dependent protein-ADP-ribosyltransferase YbiA, DUF1768 family	162
2918241460	312	93.04	1	312	10	303	9.8e-85	278.8	COG4227	Antirestriction protein ArdC	316
2918241469	78	26.11	2	78	27	85	3.4e-09	30.8	COG2135	Putative SOS response-associated peptidase YedK	226
2918241470	142	58.62	11	141	83	201	3.0e-30	99.6	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2918241471	324	81.55	7	321	1	305	2.9e-59	195.4	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918241476	502	53.91	56	155	16	77	4.9e-05	17	COG4467	Regulator of replication initiation timing	114
2918241480	125	8.25	21	122	120	177	3.8e-04	13.4	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
2918241484	403	95	2	121	6	119	8.3e-31	100.2	COG5499	Antitoxin component HigA of the HigAB toxin-antitoxin module, contains an N-terminal HTH domain	120
2918241485	87	76.53	1	86	2	76	9.5e-04	14.2	COG4680	mRNA-degrading endonuclease (mRNA interferase) HigB, toxic component of the HigAB toxin-antitoxin module	98
2918241494	164	62.95	11	164	84	224	3.7e-47	154.9	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
2918241498	655	97.04	1	608	1	558	0.0e+00	499.3	COG0550	DNA topoisomerase IA	570
2918241500	87	18.58	13	87	12	71	1.3e-03	12.1	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918241501	142	74.85	1	142	2	129	1.7e-20	68.6	COG0629	Single-stranded DNA-binding protein	167
2918241507	292	98.11	1	270	2	260	1.3e-45	150.5	COG1192	Cellulose biosynthesis protein BcsQ	259
2918241508	69	88.57	1	68	5	66	1.2e-22	74	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2918241509	245	41.74	121	207	16	63	1.7e-03	12.4	COG4467	Regulator of replication initiation timing	114
2918241510	66	7.67	1	66	417	463	6.2e-14	45.5	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2918241511	79	14.86	1	79	457	538	2.3e-18	60.1	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918241512	265	33.64	1	265	513	772	2.9e-73	241.7	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
2918241513	108	27.92	1	106	9	87	7.2e-13	42.9	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918241514	182	12.37	87	151	112	160	2.2e-17	14.1	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918241514	182	20.96	6	96	12	94	2.2e-17	48.2	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918241515	651	26.84	36	190	5	135	1.9e-42	73.3	COG3119	Arylsulfatase A or related enzyme	475
2918241515	651	48.16	148	450	235	469	1.9e-42	67.7	COG3119	Arylsulfatase A or related enzyme	475
2918241516	795	98.98	72	612	2	484	0.0e+00	440.6	COG3119	Arylsulfatase A or related enzyme	475
2918241517	331	80.78	4	331	62	330	1.1e-75	249.3	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918241519	332	95.71	32	331	5	294	1.9e-37	118	COG1234	Ribonuclease BN, tRNA processing enzyme	292
2918241520	507	92.62	30	480	4	455	6.0e-71	234.3	COG3119	Arylsulfatase A or related enzyme	475
2918241521	466	42.01	233	451	264	468	1.5e-86	130.7	COG3119	Arylsulfatase A or related enzyme	475
2918241521	466	43.03	25	247	4	213	1.5e-86	157.4	COG3119	Arylsulfatase A or related enzyme	475
2918241522	385	63.71	124	378	57	207	2.2e-09	26.6	COG0412	Dienelactone hydrolase	236
2918241523	310	30.14	150	309	3	46	9.4e-05	16.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918241524	107	88.79	1	106	7	101	3.4e-19	63	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2918241525	344	98.9	14	335	2	271	2.1e-48	159.4	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918241526	261	96.8	3	261	6	217	1.1e-27	89.6	COG1878	Kynurenine formamidase	218
2918241527	212	42.58	6	207	14	102	3.2e-17	58	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918241528	364	96.21	6	363	12	341	4.7e-51	168	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918241529	203	90.22	15	197	3	168	4.2e-25	82.8	COG0431	NAD(P)H-dependent FMN reductase	184
2918241530	806	75.3	10	366	71	384	1.4e-64	212.5	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2918241531	408	46.21	218	406	11	187	9.8e-25	16.6	COG0477	MFS family permease	338
2918241531	408	68.41	18	244	8	269	9.8e-25	68.2	COG0477	MFS family permease	338
2918241532	449	64.92	48	449	138	422	2.1e-10	32.7	COG3659	Carbohydrate-selective porin OprB	439
2918241533	405	95.99	1	405	11	417	1.6e-72	238.9	COG4949	Uncharacterized membrane-anchored protein	424
2918241534	197	79.43	1	196	9	174	2.9e-20	68.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918241535	249	98.51	1	247	4	267	8.9e-54	177.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918241536	252	96.34	8	241	9	245	4.2e-65	214	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2918241537	691	99.12	4	691	3	675	0.0e+00	545.9	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2918241538	550	97.35	1	550	5	554	7.3e-123	404.9	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
2918241539	400	98.48	6	399	3	392	1.9e-121	400	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918241540	270	61.68	1	242	3	200	4.4e-32	106.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918241541	398	96.13	6	390	3	375	5.2e-64	211.1	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918241542	561	99.28	8	559	2	552	0.0e+00	581.7	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918241543	482	98.33	12	482	4	474	0.0e+00	604.5	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918241544	823	95.85	105	823	34	795	1.6e-62	206.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918241545	317	96.59	1	317	11	322	4.9e-86	282.9	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918241546	128	67.2	1	127	51	175	1.8e-26	87.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918241547	241	95.85	3	241	6	236	1.6e-52	172.5	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918241548	241	95.85	4	241	7	237	1.9e-53	175.6	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918241549	383	94.26	11	380	9	353	3.0e-80	264.1	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918241550	312	98.34	4	311	3	298	1.8e-88	291.2	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918241551	415	96.28	2	378	11	321	4.6e-92	302.7	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918241552	257	99.61	1	253	2	254	4.6e-102	334.9	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918241553	238	99.16	2	238	2	236	1.0e-95	313.7	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918241554	115	85.29	2	115	18	133	1.6e-22	74.3	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918241555	469	96.97	1	461	5	452	0.0e+00	510.2	COG1113	L-asparagine transporter and related permeases	462
2918241556	213	92	1	213	5	211	1.1e-78	258.1	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
2918241557	231	98.64	2	223	2	218	5.2e-85	278.4	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
2918241558	278	99.59	25	270	1	245	2.8e-62	204.1	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918241559	466	82.23	110	466	64	387	2.9e-50	165.8	COG0642	Signal transduction histidine kinase	336
2918241560	240	98.71	5	236	2	230	4.3e-80	262.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918241562	1073	99.7	3	1057	2	1012	0.0e+00	800.8	COG0841	Multidrug efflux pump subunit AcrB	1009
2918241563	388	97.44	8	382	8	387	1.1e-46	154	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918241564	464	97.83	11	464	1	450	1.1e-95	315.6	COG1538	Outer membrane protein TolC	457
2918241565	461	53.52	268	460	5	209	2.7e-43	30.2	COG0477	MFS family permease	338
2918241565	461	74.67	30	299	4	289	2.7e-43	121	COG0477	MFS family permease	338
2918241566	309	96.99	6	309	5	294	8.2e-68	222.7	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918241569	106	53.85	1	95	4	66	1.6e-15	51.9	COG2963	Transposase and inactivated derivatives	116
2918241570	106	58.9	4	106	40	135	4.9e-12	40.2	COG3436	Transposase	157
2918241571	244	73.62	95	220	4	123	2.5e-27	89.4	COG3436	Transposase	157
2918241573	267	94.79	1	265	7	279	6.8e-67	219.7	COG0682	Prolipoprotein diacylglyceryltransferase	287
2918241576	128	15.95	47	122	194	230	1.0e-16	24	COG3039	Transposase and inactivated derivatives, IS5 family	230
2918241576	128	17.67	1	54	4	44	1.0e-16	30.5	COG3039	Transposase and inactivated derivatives, IS5 family	230
2918241577	232	70.12	9	227	45	220	2.8e-33	108.5	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918241578	160	95.57	5	159	3	153	6.7e-37	121.3	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918241579	344	87.9	3	344	13	317	3.8e-96	316.4	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2918241580	312	96.54	1	311	10	316	0.0e+00	435.8	COG4874	Uncharacterized protein	318
2918241581	341	92.42	1	314	25	329	1.7e-90	298.1	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2918241582	140	91.77	1	140	6	150	3.7e-31	102.8	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918241583	433	91.34	1	431	35	456	0.0e+00	479.6	COG1113	L-asparagine transporter and related permeases	462
2918241585	212	87.74	12	212	11	196	2.2e-49	162.3	COG0684	Regulator of RNase E activity RraA	210
2918241586	324	96.63	1	322	4	318	3.9e-92	302.9	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918241587	446	47.78	248	437	8	190	1.7e-38	21.5	COG0477	MFS family permease	338
2918241587	446	55.09	22	260	2	212	1.7e-38	112	COG0477	MFS family permease	338
2918241588	506	56.91	18	167	4	143	5.7e-51	57.1	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918241588	506	98.78	257	499	2	244	5.7e-51	109.3	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918241589	457	97.67	194	451	4	254	3.1e-84	276.1	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918241590	71	4.64	5	57	967	1013	1.0e-09	31.4	COG0841	Multidrug efflux pump subunit AcrB	1009
2918241592	589	97.36	3	587	6	558	4.6e-55	181.7	COG2303	Choline dehydrogenase or related flavoprotein	542
2918241593	440	17.68	10	92	57	85	2.2e-34	7	COG2010	Cytochrome c, mono- and diheme variants	150
2918241593	440	69.51	302	438	47	160	2.2e-34	44.4	COG2010	Cytochrome c, mono- and diheme variants	150
2918241593	440	100	127	301	1	164	2.2e-34	68.2	COG2010	Cytochrome c, mono- and diheme variants	150
2918241595	582	94.62	24	574	7	516	0.0e+00	612.7	COG1292	Choline-glycine betaine transporter	537
2918241596	249	94.98	9	248	5	250	1.3e-17	58.3	COG0730	Uncharacterized membrane protein YfcA	258
2918241597	267	98.04	3	256	4	253	9.4e-81	265.2	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
2918241598	250	98.07	1	250	3	256	3.7e-09	30.7	COG0730	Uncharacterized membrane protein YfcA	258
2918241599	353	98.8	22	353	1	330	3.5e-81	267.5	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918241600	584	93.41	3	569	4	542	0.0e+00	582.4	COG4146	Uncharacterized membrane permease YidK, sodium:solute symporter family	571
2918241601	679	72.58	90	679	117	685	0.0e+00	438	COG1501	Alpha-glucosidase, glycosyl hydrolase family GH31	772
2918241602	366	82.22	34	366	45	340	8.8e-18	58.1	COG3203	Outer membrane protein (porin)	354
2918241603	305	95.53	2	299	10	308	5.9e-53	174.4	COG2017	Galactose mutarotase or related enzyme	308
2918241604	291	94.82	1	289	17	309	3.0e-82	270.5	COG3386	Sugar lactone lactonase YvrE	307
2918241605	260	98.88	10	258	2	266	1.7e-62	205.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918241606	579	98.44	2	569	8	576	0.0e+00	549.4	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918241607	486	98.75	12	484	2	474	0.0e+00	619.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918241609	283	93.81	5	283	10	282	5.0e-109	358.4	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
2918241610	334	97.05	1	330	9	304	7.3e-77	252.8	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
2918241611	279	80.26	8	279	58	301	2.6e-52	172.5	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2918241612	267	98.49	3	264	5	265	3.1e-69	227.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918241613	434	53.26	4	223	8	211	7.5e-22	54.8	COG0477	MFS family permease	338
2918241613	434	54.31	226	430	2	209	7.5e-22	24.1	COG0477	MFS family permease	338
2918241614	209	86.6	5	204	17	197	4.6e-15	51.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918241615	254	99.63	1	253	1	267	4.8e-61	201.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918241616	545	97.97	1	542	10	540	0.0e+00	587.9	COG1021	Non-ribosomal peptide synthetase component E (peptide arylation enzyme)	542
2918241617	256	93.96	1	256	7	255	6.1e-72	236.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918241618	397	99.75	1	395	1	393	7.0e-120	395.1	COG0183	Acetyl-CoA acetyltransferase	392
2918241619	312	98.03	1	312	7	305	5.0e-70	230.7	COG4313	Uncharacterized conserved protein	304
2918241620	169	58.77	35	169	8	131	3.1e-34	113.2	COG3109	sRNA-binding protein	208
2918241621	164	41.22	1	164	227	388	5.4e-55	181.2	COG3004	Na+/H+ antiporter NhaA	390
2918241625	411	71.33	4	346	5	325	3.4e-16	53.1	COG0439	Biotin carboxylase	449
2918241626	417	93	2	404	11	382	3.3e-49	161.9	COG0475	Kef-type K+ transport system, membrane component KefB	397
2918241627	285	94.02	1	285	12	294	4.3e-18	59.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918241628	310	98.01	14	309	3	297	2.0e-51	169.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241629	394	96.69	8	394	7	386	0.0e+00	466.8	COG3004	Na+/H+ antiporter NhaA	390
2918241630	319	89.85	1	312	17	317	5.9e-57	187.7	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918241631	320	94.33	1	320	8	323	8.2e-68	223.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918241633	164	97.6	1	164	3	165	1.1e-57	188.8	COG3749	Uncharacterized conserved protein, DUF934 family	167
2918241634	550	99.81	1	545	1	513	0.0e+00	584.2	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2918241637	1235	98.72	4	330	4	311	1.1e-129	425.7	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
2918241637	1235	100	331	1201	1	857	0.0e+00	1314.9	COG1410	Methionine synthase I, cobalamin-binding domain	842
2918241639	344	93.32	1	343	15	377	2.8e-46	152.5	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918241640	194	95.7	101	192	3	91	2.2e-28	92.3	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
2918241641	202	90	8	200	19	207	2.2e-45	149	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
2918241642	161	89.61	6	161	12	149	2.2e-43	142	COG2847	Copper(I)-binding protein	151
2918241644	277	78.79	149	276	22	125	2.2e-30	98.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918241645	104	95.33	1	103	5	106	1.6e-30	100.1	COG4392	Branched-chain amino acid transport protein	107
2918241646	233	92.05	1	233	9	228	1.9e-64	211.9	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
2918241647	231	22.36	12	227	98	171	6.0e-06	20.2	COG0790	TPR repeat	292
2918241649	212	95.19	2	207	5	202	1.4e-34	113.3	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918241650	212	77.82	1	206	44	243	6.5e-34	111.7	COG3403	Uncharacterized protein YcgG, contains conserved FPC and CPF motifs	257
2918241651	306	97.34	7	298	3	295	1.4e-52	173.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241652	303	97.01	2	297	6	297	5.5e-74	243.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241653	403	96.71	15	400	8	389	4.9e-88	289.6	COG2814	Predicted arabinose efflux permease, MFS family	394
2918241654	788	97.08	1	787	11	776	0.0e+00	472.6	COG0417	DNA polymerase elongation subunit (family B)	792
2918241656	382	95.08	193	372	8	181	5.6e-47	154.1	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918241658	160	98.68	1	153	2	150	2.5e-61	200.6	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
2918241659	449	67.99	5	263	82	321	4.4e-05	16.9	COG1413	HEAT repeat	335
2918241661	151	34.62	1	101	27	71	9.2e-07	24.3	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918241662	299	97.34	1	292	2	294	3.9e-43	142.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918241663	389	97.68	2	389	5	383	8.1e-53	174.4	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918241664	259	96.67	1	259	10	270	2.7e-97	319.5	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
2918241666	617	98.99	23	604	6	591	0.0e+00	487.2	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918241669	256	77.99	8	253	5	213	4.2e-28	93	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918241671	297	94.82	1	295	15	307	2.3e-83	274.2	COG3386	Sugar lactone lactonase YvrE	307
2918241672	275	59.19	10	224	3	192	2.4e-33	109.9	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918241674	384	93.3	1	383	20	367	6.4e-76	249.9	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918241675	536	95.5	2	535	18	569	1.7e-83	275.8	COG0747	ABC-type transport system, periplasmic component	556
2918241676	345	97.48	8	345	6	315	5.4e-107	352.2	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918241677	536	97.23	1	535	9	570	1.7e-85	282.4	COG0747	ABC-type transport system, periplasmic component	556
2918241678	301	91.28	6	301	24	295	8.0e-102	334.6	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918241679	279	84.62	5	278	2	276	4.0e-99	326	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918241680	258	98.82	1	252	2	253	5.0e-95	312.1	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
2918241681	595	96.94	28	592	3	541	1.2e-103	342.5	COG5434	Polygalacturonase	542
2918241682	247	97.1	6	244	5	238	1.1e-56	186.2	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918241683	235	93.78	3	231	6	231	1.6e-55	182.3	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918241684	633	97.93	5	633	14	627	0.0e+00	883.1	COG3158	K+ transporter	627
2918241685	473	98.2	51	473	2	382	1.1e-58	193	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918241686	165	86.76	4	165	17	134	2.9e-24	79.8	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918241687	315	93.33	1	313	5	312	3.0e-88	290.5	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2918241688	325	91.91	5	325	7	324	6.8e-102	335.4	COG1171	Threonine dehydratase	347
2918241689	201	93.64	1	201	11	216	6.1e-53	174	COG2964	Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains	220
2918241690	136	97.95	7	133	2	144	8.5e-15	50.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918241691	333	100	1	327	1	331	3.3e-88	290.6	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918241692	478	98.12	8	478	3	472	0.0e+00	528.6	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918241693	309	97.67	2	300	2	295	1.8e-62	206.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241694	491	51.24	2	142	118	241	1.6e-29	23.5	COG2202	PAS domain	232
2918241694	491	59.92	60	244	74	218	1.6e-29	29.4	COG2202	PAS domain	232
2918241694	491	76.25	413	488	18	78	1.5e-20	65.8	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918241694	491	77.69	204	385	55	242	1.6e-29	55.7	COG2202	PAS domain	232
2918241695	328	69.23	232	321	27	98	8.2e-02	11.2	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2918241697	803	95.14	75	803	36	720	0.0e+00	704.4	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
2918241699	229	96.51	1	227	5	225	1.1e-74	244.9	COG3382	B3/B4 domain (DNA/RNA-binding domain of Phe-tRNA-synthetase)	229
2918241700	125	24.82	88	125	105	139	7.5e-20	22.2	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2918241700	125	41.84	26	89	5	63	7.5e-20	48.2	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2918241702	153	58.72	1	139	18	118	4.1e-16	53.8	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918241706	325	21.99	237	324	292	375	2.8e-57	17.2	COG3268	Uncharacterized conserved protein, related to short-chain dehydrogenases	382
2918241706	325	64.92	1	240	8	255	2.8e-57	170.9	COG3268	Uncharacterized conserved protein, related to short-chain dehydrogenases	382
2918241707	133	97.95	1	126	3	145	4.2e-09	31.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918241708	247	97.39	1	246	7	267	4.3e-59	194.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918241709	297	79.55	169	296	22	126	4.2e-24	78.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918241711	297	96.68	4	297	2	292	2.2e-71	235.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241712	350	94.16	45	350	18	307	8.0e-39	127.9	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
2918241713	257	55.65	15	120	49	117	1.1e-20	22.2	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918241713	257	73.39	129	257	26	116	1.1e-20	45.7	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918241714	155	95.42	19	148	6	130	9.4e-35	113.7	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918241715	196	94.77	37	193	3	147	4.8e-19	63.5	COG0716	Flavodoxin	151
2918241716	329	98.12	1	316	1	314	1.6e-107	353.4	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918241717	238	50.9	13	234	56	197	3.6e-07	25.2	COG0500	SAM-dependent methyltransferase	257
2918241719	98	27.51	12	94	139	223	2.5e-05	17.9	COG0010	Arginase family enzyme	305
2918241721	737	96.23	25	737	31	795	6.7e-54	178.2	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918241722	329	96.25	8	327	8	315	1.4e-81	268	COG4607	ABC-type enterochelin transport system, periplasmic component	320
2918241723	258	99.6	1	252	1	251	1.6e-102	336.8	COG4604	ABC-type enterochelin transport system, ATPase component	252
2918241724	313	95.57	2	312	13	314	3.8e-85	280.2	COG4605	ABC-type enterochelin transport system, permease component	316
2918241725	313	95.33	1	313	11	316	3.7e-114	375.6	COG4606	ABC-type enterochelin transport system, permease component	321
2918241726	585	95.78	2	571	20	586	1.2e-118	391.6	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918241727	597	97.3	19	587	14	589	0.0e+00	440.3	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918241728	185	79.9	4	181	34	200	3.4e-07	25.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918241730	408	97.47	13	403	4	388	1.6e-99	327.4	COG2814	Predicted arabinose efflux permease, MFS family	394
2918241732	297	97.67	9	297	2	295	4.3e-61	201.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241733	234	97.76	1	231	5	266	2.6e-55	182.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918241734	421	89.91	1	421	38	447	3.3e-102	337	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918241735	289	96.01	1	286	3	291	1.1e-34	114.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918241736	151	96.58	3	148	2	142	8.1e-53	172.3	COG0757	3-dehydroquinate dehydratase	146
2918241737	439	45.95	222	423	10	185	2.8e-37	27.9	COG0477	MFS family permease	338
2918241737	439	63.45	2	255	6	248	2.8e-37	98.8	COG0477	MFS family permease	338
2918241738	303	96.68	1	298	1	291	1.3e-56	186.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241739	203	26.44	105	203	213	290	3.1e-22	43.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918241739	203	37.29	2	129	24	133	3.1e-22	34.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918241740	388	96.2	1	384	12	391	1.7e-118	390	COG2814	Predicted arabinose efflux permease, MFS family	394
2918241741	288	96.35	1	288	6	295	4.3e-69	228	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241743	106	61.54	1	95	4	75	1.3e-15	52.2	COG2963	Transposase and inactivated derivatives	116
2918241744	111	57.67	4	104	40	133	2.6e-15	50.7	COG3436	Transposase	157
2918241748	437	96.41	19	436	4	406	0.0e+00	480.5	COG1301	Na+/H+-dicarboxylate symporter	415
2918241749	287	97.86	14	287	5	278	3.6e-52	172	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2918241752	204	66.78	1	204	1	201	1.6e-47	157.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241753	307	94.41	3	279	2	271	1.5e-28	94.1	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918241754	362	98.94	1	356	2	375	0.0e+00	468.1	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
2918241755	238	97.64	10	223	4	210	1.3e-64	212.1	COG0684	Regulator of RNase E activity RraA	210
2918241756	245	96.34	1	245	7	243	4.7e-52	171.6	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
2918241757	402	27.24	7	99	2	83	2.9e-73	79.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241757	402	97.34	103	401	4	296	2.9e-73	167.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241758	119	77.59	2	115	25	114	1.3e-24	80.6	COG3450	Predicted enzyme of the cupin superfamily	116
2918241759	199	80.95	1	190	14	166	9.7e-15	49.1	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918241760	377	88.25	14	377	27	364	5.2e-77	253.6	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
2918241761	233	99.46	27	219	1	183	6.7e-49	160.4	COG0431	NAD(P)H-dependent FMN reductase	184
2918241762	156	95.27	1	135	3	143	3.5e-23	76.6	COG0394	Protein-tyrosine-phosphatase	139
2918241763	33	7.08	1	30	395	424	2.7e-06	20.8	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
2918241764	115	70.34	2	102	17	99	6.6e-19	62.9	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918241765	180	57.3	1	175	2	107	1.1e-06	23.3	COG0563	Adenylate kinase or related kinase	178
2918241767	516	58.26	6	310	99	239	2.3e-06	21.7	COG2202	PAS domain	232
2918241767	516	91.23	295	516	3	210	1.4e-40	132.7	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918241768	688	67.01	183	544	128	391	4.1e-52	172.7	COG0642	Signal transduction histidine kinase	336
2918241769	808	95.56	91	808	33	720	0.0e+00	714.9	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
2918241770	324	98.14	1	322	7	323	3.4e-81	267.1	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918241771	173	81.18	8	163	19	169	2.2e-32	106.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918241772	66	81.08	1	66	5	64	6.6e-13	43.2	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
2918241777	455	85.32	46	320	47	325	1.2e-68	225.6	COG3344	Retron-type reverse transcriptase	328
2918241778	441	91.56	11	441	25	436	1.5e-29	97.5	COG2271	Sugar phosphate permease	448
2918241779	317	98.01	15	308	2	296	1.6e-50	167	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241780	275	97.86	2	275	6	279	7.5e-45	148	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2918241781	449	90.89	5	441	24	432	1.5e-33	110.5	COG2271	Sugar phosphate permease	448
2918241782	246	99.25	3	245	2	267	1.1e-65	216.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918241783	265	55.04	3	259	122	274	5.7e-16	52.9	COG1082	Sugar phosphate isomerase/epimerase	274
2918241786	714	81.65	301	704	79	425	3.1e-71	234.9	COG0840	Methyl-accepting chemotaxis protein	408
2918241787	169	88.71	1	169	9	173	1.9e-39	129.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918241788	314	96.28	3	314	11	321	2.3e-85	280.7	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918241789	831	98.24	23	831	15	795	3.7e-106	350.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918241790	322	92.35	3	321	24	325	8.1e-79	259.2	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918241791	463	95.62	23	415	4	374	6.4e-58	191.1	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918241792	112	87.5	1	111	12	130	5.0e-23	75.9	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918241793	116	93.97	1	116	6	114	5.7e-31	101.3	COG3450	Predicted enzyme of the cupin superfamily	116
2918241794	305	72.16	4	304	4	283	0.0e+00	472.1	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
2918241795	317	94.85	5	293	7	282	1.5e-113	373.2	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
2918241796	342	97.05	8	338	8	303	2.6e-73	241	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
2918241797	176	76.03	66	176	12	122	6.0e-04	14.9	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918241798	539	91.28	7	536	10	501	0.0e+00	541.3	COG1292	Choline-glycine betaine transporter	537
2918241799	375	97.76	31	315	6	267	3.0e-80	263.6	COG1018	Ferredoxin-NADP reductase	266
2918241800	397	95.48	1	397	10	368	4.1e-67	221.4	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918241801	314	96.68	18	312	5	295	6.6e-54	178	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241802	483	98.54	6	483	3	474	0.0e+00	529.9	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918241803	341	96.31	4	324	7	319	3.3e-83	273.5	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918241808	258	95.52	2	251	1	256	2.1e-37	123.3	COG0345	Pyrroline-5-carboxylate reductase	266
2918241809	439	95.62	31	413	2	372	2.0e-55	182.9	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918241810	263	85.16	1	258	30	270	7.1e-23	75.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918241812	816	94.44	81	816	41	720	0.0e+00	745.5	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
2918241813	317	98.14	2	316	6	322	2.3e-91	300.4	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918241814	172	87.63	1	164	11	173	1.5e-38	126.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918241815	155	88.89	20	155	12	139	2.3e-24	80.8	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918241817	277	95.04	4	275	3	270	3.5e-97	319.2	COG3220	Uncharacterized conserved protein, UPF0276 family	282
2918241818	95	85.58	1	94	14	102	1.0e-31	103.6	COG5572	Uncharacterized membrane protein	104
2918241819	195	94.62	17	194	6	181	1.7e-35	116.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918241820	213	100	1	213	1	213	1.2e-45	150.3	COG4944	Uncharacterized protein	213
2918241821	307	93.99	108	296	5	176	8.8e-49	159	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918241822	935	94.38	21	536	23	543	1.3e-71	235.3	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918241823	348	98.58	1	348	1	346	2.5e-59	195	COG0673	Predicted dehydrogenase	342
2918241824	274	88.13	4	272	13	257	6.4e-26	85.6	COG1082	Sugar phosphate isomerase/epimerase	274
2918241825	284	98.37	14	264	3	244	8.2e-60	196.1	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918241826	571	11.66	497	570	348	413	8.8e-47	19.3	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918241826	571	85.51	5	509	3	486	8.8e-47	134.3	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918241827	809	95.42	87	809	34	720	0.0e+00	861	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
2918241828	319	97.52	1	319	8	322	1.4e-88	291.3	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918241829	176	85.48	3	167	15	173	6.2e-33	108.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918241830	731	81.75	1	130	20	131	2.7e-08	27.6	COG1765	Uncharacterized OsmC-related protein	137
2918241830	731	98.5	144	571	4	398	3.6e-124	408.5	COG1944	Ribosomal protein S12 methylthiotransferase accessory factor YcaO	398
2918241831	59	71.62	2	59	6	58	6.6e-13	43.1	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
2918241833	788	98.11	69	788	16	795	2.0e-114	378.3	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918241834	313	95.36	3	313	13	320	3.0e-67	221.2	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918241835	172	89.78	3	172	10	176	2.1e-31	103.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918241836	142	78.75	4	137	15	140	4.9e-15	50.1	COG4244	Uncharacterized membrane protein	160
2918241837	430	96.85	2	430	12	411	3.3e-122	402.8	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2918241838	500	48.56	257	466	5	190	4.2e-42	39.5	COG0477	MFS family permease	338
2918241838	500	74.41	23	288	4	288	4.2e-42	104.7	COG0477	MFS family permease	338
2918241839	297	89.42	1	280	25	269	7.7e-68	223.1	COG1718	Serine/threonine-protein kinase RIO1	268
2918241840	119	58.11	61	118	18	60	1.3e-10	6.8	COG3729	General stress protein YciG, contains tandem KGG domains	73
2918241840	119	60.81	42	93	24	68	1.3e-10	24.8	COG3729	General stress protein YciG, contains tandem KGG domains	73
2918241840	119	70.27	4	67	17	68	1.3e-10	23.6	COG3729	General stress protein YciG, contains tandem KGG domains	73
2918241841	245	96.33	5	210	7	216	1.7e-16	54.6	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918241842	375	85.56	60	302	25	267	5.6e-18	59.2	COG2801	Transposase InsO and inactivated derivatives	232
2918241843	2876	14.11	1565	1746	293	441	0.0e+00	34.6	COG3459	Cellobiose phosphorylase	1056
2918241843	2876	99.53	1782	2869	2	1052	0.0e+00	1001.3	COG3459	Cellobiose phosphorylase	1056
2918241845	221	96.46	1	220	2	219	1.3e-69	228.3	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918241846	820	30	236	372	280	402	9.3e-24	12.7	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2918241846	820	31.95	685	815	279	409	9.3e-24	38.1	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2918241846	820	43.41	445	613	14	191	9.3e-24	22.8	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2918241847	354	92.96	18	354	26	355	1.7e-117	386.8	COG5621	Predicted secreted hydrolase	354
2918241848	142	37.29	2	129	190	302	1.1e-25	84.8	COG1234	Ribonuclease BN, tRNA processing enzyme	292
2918241849	218	49.5	1	191	2	151	9.5e-37	121.3	COG1234	Ribonuclease BN, tRNA processing enzyme	292
2918241850	184	94.86	2	183	6	171	2.8e-62	203.4	COG3040	Bacterial lipocalin	174
2918241851	286	94.68	1	286	10	294	1.1e-72	239.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241852	359	98.41	1	355	3	374	0.0e+00	467.5	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
2918241853	434	99.77	1	433	1	435	0.0e+00	559.8	COG2851	Mg2+/citrate symporter	433
2918241856	356	96.02	12	355	11	348	2.4e-84	277.5	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
2918241857	300	98.34	1	298	1	296	2.2e-63	209.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241858	237	95.83	1	236	8	237	3.4e-46	151.9	COG5343	Anti-sigma-K factor RskA	240
2918241859	186	92.47	9	186	6	177	5.3e-43	141.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918241861	410	98.56	28	410	5	416	7.3e-65	214.1	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918241862	303	98.34	5	303	3	298	4.5e-65	214.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241863	336	99.7	1	335	1	330	2.2e-80	264.9	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918241865	461	50.65	241	454	9	202	3.0e-37	27.1	COG0477	MFS family permease	338
2918241865	461	70.5	16	272	8	277	3.0e-37	97.4	COG0477	MFS family permease	338
2918241866	177	76.47	6	176	21	163	1.4e-19	65.3	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918241867	212	93.49	4	208	2	202	3.4e-36	119.4	COG0625	Glutathione S-transferase	211
2918241868	704	97.99	6	704	15	793	7.1e-46	146.1	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918241869	584	95.5	14	582	17	568	4.5e-88	290.8	COG0747	ABC-type transport system, periplasmic component	556
2918241870	310	98.11	2	310	4	315	9.9e-87	285.6	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918241871	418	87.97	3	391	29	379	4.8e-46	151.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918241872	450	97.08	13	419	10	342	2.6e-91	300.5	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918241873	351	98.44	1	351	1	315	1.3e-102	337.4	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918241874	285	88.93	2	284	25	289	4.6e-82	269.5	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918241875	550	98.91	5	540	4	549	0.0e+00	594.1	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918241876	299	96.68	2	299	5	295	8.4e-66	217.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241877	399	96.2	7	399	9	388	2.6e-38	125.9	COG2814	Predicted arabinose efflux permease, MFS family	394
2918241878	284	98.14	24	283	4	214	1.2e-51	169.8	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
2918241879	721	95.6	9	721	26	785	2.7e-66	219.1	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918241880	544	95.85	5	544	14	567	2.6e-87	288.5	COG0747	ABC-type transport system, periplasmic component	556
2918241881	329	97.17	18	328	7	315	7.8e-88	289.2	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918241882	287	90.27	4	287	26	294	7.9e-84	275.5	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918241883	344	64.49	1	344	2	357	2.4e-108	357.6	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918241884	225	32.77	7	193	355	529	8.5e-67	220.1	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
2918241885	403	95.49	3	398	15	395	3.7e-54	178.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918241886	460	40.99	288	459	34	190	2.8e-40	22.2	COG0477	MFS family permease	338
2918241886	460	78.59	12	301	8	308	2.8e-40	114.5	COG0477	MFS family permease	338
2918241887	367	54.48	12	344	248	551	1.6e-121	401.4	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
2918241888	395	95.74	1	390	13	394	9.6e-54	177.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918241890	628	98.1	6	616	4	623	0.0e+00	555.4	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2918241891	527	12.47	39	152	160	212	5.4e-107	2.4	COG0840	Methyl-accepting chemotaxis protein	408
2918241891	527	83.53	123	527	71	425	5.4e-107	352	COG0840	Methyl-accepting chemotaxis protein	408
2918241893	496	98.96	18	496	2	475	0.0e+00	554.3	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918241894	460	98.66	9	457	3	443	0.0e+00	497.6	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918241895	459	88.62	21	456	11	446	6.0e-66	217.1	COG0531	Amino acid transporter	466
2918241896	307	94.75	7	303	16	304	2.0e-93	307.2	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
2918241897	301	94.88	18	269	5	245	1.5e-88	290.7	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
2918241898	286	99.64	1	273	1	275	1.2e-88	291.5	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2918241899	283	95.29	3	271	4	266	6.7e-84	275.8	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2918241900	595	98.92	2	565	3	551	0.0e+00	494.8	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918241901	167	90.18	2	160	13	159	2.4e-44	144.9	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
2918241903	201	8.39	9	166	239	309	3.6e-03	10.1	COG1511	Uncharacterized membrane protein YhgE, phage infection protein (PIP) family	780
2918241905	268	74.29	144	248	19	96	2.2e-02	9.3	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
2918241906	64	19.6	1	63	231	289	1.0e-06	23.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241909	213	82.71	1	213	30	249	8.3e-55	180.6	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
2918241911	741	85.52	8	227	5	193	6.8e-42	137.7	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2918241912	393	91.88	7	393	29	390	2.9e-45	149.9	COG0642	Signal transduction histidine kinase	336
2918241913	271	93.9	3	265	16	292	1.8e-38	127.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918241916	594	98.06	1	593	3	559	1.4e-85	282.6	COG2303	Choline dehydrogenase or related flavoprotein	542
2918241917	415	26.22	2	67	44	86	6.1e-44	15.7	COG2010	Cytochrome c, mono- and diheme variants	150
2918241917	415	59.15	296	415	62	158	6.1e-44	37.9	COG2010	Cytochrome c, mono- and diheme variants	150
2918241917	415	100	103	285	1	164	6.1e-44	96.3	COG2010	Cytochrome c, mono- and diheme variants	150
2918241918	340	99.7	12	340	1	333	1.3e-82	272.1	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918241919	261	70.5	6	221	15	210	2.1e-06	17.6	COG1082	Sugar phosphate isomerase/epimerase	274
2918241920	316	98.1	5	313	1	310	3.1e-71	234.3	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918241921	430	91.11	5	421	28	437	6.5e-38	124.9	COG2271	Sugar phosphate permease	448
2918241922	327	99.69	1	320	1	326	2.2e-104	343.3	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918241926	167	39.44	8	118	58	113	3.2e-03	11.8	COG1569	Predicted nucleic acid-binding protein, contains PIN domain	142
2918241928	55	26.89	1	55	62	125	2.5e-07	25.2	COG3409	Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases	185
2918241930	128	48.84	3	124	17	100	2.8e-17	57.5	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918241931	251	98.51	2	249	2	265	1.0e-71	236.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918241932	235	90.09	2	231	18	226	6.3e-54	177.2	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918241933	341	99.71	1	339	1	340	1.1e-127	420.1	COG3938	Proline racemase	341
2918241934	493	98.96	5	486	2	475	0.0e+00	577.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918241935	426	97.94	6	424	4	383	1.2e-57	189.9	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918241936	291	97.32	1	291	3	293	1.8e-84	277.5	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918241937	221	92.98	2	219	15	226	3.2e-62	204.4	COG0765	ABC-type amino acid transport system, permease component	222
2918241938	223	92.54	1	221	14	224	8.3e-63	206.5	COG0765	ABC-type amino acid transport system, permease component	222
2918241939	273	99.17	24	270	2	241	4.7e-96	314.9	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918241941	277	94.7	4	275	3	270	1.7e-27	90.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918241942	256	98.51	6	254	3	266	1.5e-54	179.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918241943	244	94.51	1	243	1	241	3.8e-110	361.4	COG3484	Predicted proteasome-type protease	255
2918241944	259	91.72	1	259	11	320	7.1e-48	158.2	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2918241945	316	98.72	1	316	1	309	1.0e-95	315.3	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2918241946	469	96.52	1	469	8	478	0.0e+00	696.8	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
2918241951	419	97.55	123	408	7	285	1.2e-96	317.4	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2918241952	269	92.72	1	257	6	247	4.8e-61	200.2	COG3496	Uncharacterized conserved protein, DUF1365 family	261
2918241953	415	92.84	1	415	9	423	0.0e+00	525.1	COG2907	Predicted NAD/FAD-binding protein	447
2918241954	250	80.6	1	242	10	225	1.9e-41	136.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918241956	229	77.08	1	229	65	296	2.4e-36	120.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241957	369	92.01	3	366	4	337	4.7e-89	293.4	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918241958	151	50.41	2	126	121	242	9.4e-21	68.5	COG2202	PAS domain	232
2918241959	295	71.97	10	176	4	98	3.6e-21	69.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918241960	401	65.99	53	399	128	387	1.6e-50	167.2	COG0642	Signal transduction histidine kinase	336
2918241961	455	85.32	46	320	47	325	1.2e-68	225.6	COG3344	Retron-type reverse transcriptase	328
2918241964	213	91.56	1	212	5	210	5.3e-80	262.4	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
2918241965	231	98.64	2	223	2	218	2.5e-86	282.9	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
2918241966	496	99.16	21	496	2	476	0.0e+00	567.6	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918241967	300	97.99	1	295	3	295	1.7e-93	307	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918241968	423	52.48	222	421	8	208	1.9e-37	30.1	COG0477	MFS family permease	338
2918241968	423	72.58	1	262	9	286	1.9e-37	97.3	COG0477	MFS family permease	338
2918241969	439	95.36	31	411	3	372	2.0e-59	196.1	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918241970	337	96.62	22	336	4	317	1.9e-84	277.7	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918241971	447	95.64	59	445	12	384	8.5e-55	180.6	COG0006	Xaa-Pro aminopeptidase	384
2918241972	411	98.14	14	407	4	372	2.1e-88	291.4	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918241973	322	98.34	16	321	2	297	4.8e-58	191.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241974	312	98.01	8	309	2	296	1.5e-59	196.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241975	187	77.5	116	187	12	73	2.5e-18	59.3	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918241976	447	52.48	237	443	8	208	1.6e-41	43.8	COG0477	MFS family permease	338
2918241976	447	54.57	11	236	3	211	1.6e-41	99.3	COG0477	MFS family permease	338
2918241977	325	99.69	1	325	2	318	5.0e-99	325.9	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
2918241978	310	96.68	14	303	7	297	1.2e-39	130.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918241981	398	97.97	1	390	4	390	3.0e-113	372.7	COG2814	Predicted arabinose efflux permease, MFS family	394
2918241982	349	98.83	1	346	3	339	1.4e-129	426.3	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2918241983	310	81.06	173	302	15	121	2.3e-26	86.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918241984	152	95.51	1	151	4	152	3.1e-57	187	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918241985	749	98.52	18	748	4	737	2.5e-116	384.4	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918241986	450	31.1	6	100	42	92	3.7e-38	12.1	COG2010	Cytochrome c, mono- and diheme variants	150
2918241986	450	59.76	314	439	62	159	3.7e-38	41	COG2010	Cytochrome c, mono- and diheme variants	150
2918241986	450	100	128	307	1	164	3.7e-38	77.1	COG2010	Cytochrome c, mono- and diheme variants	150
2918241987	336	97.01	7	334	4	295	2.7e-81	267.4	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2918241990	356	97.81	1	325	1	313	4.0e-101	332.4	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918241991	1595	97.23	10	927	4	844	0.0e+00	900	COG1201	Lhr-like helicase	814
2918241992	322	76.52	196	320	23	123	1.2e-24	80.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918241993	416	96.46	20	405	8	388	7.6e-103	338.3	COG2814	Predicted arabinose efflux permease, MFS family	394
2918241994	360	98.94	1	356	2	375	0.0e+00	448.1	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
2918241995	238	95.28	11	223	8	209	2.6e-63	207.7	COG0684	Regulator of RNase E activity RraA	210
2918241996	244	93.9	2	243	11	241	1.9e-48	159.6	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
2918241997	397	29.9	7	101	1	90	2.5e-70	90.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241997	397	97.01	99	397	4	295	2.5e-70	147.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918241999	449	52.22	255	449	4	203	2.0e-44	45.3	COG0477	MFS family permease	338
2918241999	449	55.35	24	248	4	215	2.0e-44	107.7	COG0477	MFS family permease	338
2918242000	153	82.42	4	111	3	77	1.4e-03	12.2	COG2026	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system	90
2918242001	105	59.34	1	102	1	54	1.8e-13	45.2	COG2002	Bifunctional DNA-binding transcriptional regulator of stationary/sporulation/toxin gene expression and antitoxin component of the YhaV-PrlF toxin-antitoxin module	89
2918242004	511	98.77	96	257	3	163	4.3e-40	130.8	COG3436	Transposase	157
2918242005	111	57.67	4	104	40	133	2.6e-15	50.7	COG3436	Transposase	157
2918242006	106	61.54	1	95	4	75	1.3e-15	52.2	COG2963	Transposase and inactivated derivatives	116
2918242008	1367	23.01	1250	1343	2	82	3.4e-56	25.4	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918242008	1367	56.25	2	210	150	347	3.4e-56	158.1	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918242008	1367	64.72	908	1235	135	389	8.4e-62	202.8	COG0642	Signal transduction histidine kinase	336
2918242008	1367	97.41	234	503	6	268	1.2e-79	260.6	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918242010	126	66.67	1	92	5	70	1.4e-05	20	COG3668	Plasmid stabilization system protein ParE	98
2918242011	70	79.73	2	70	14	72	4.5e-20	65.8	COG3729	General stress protein YciG, contains tandem KGG domains	73
2918242012	128	56.98	1	125	15	112	2.2e-18	61	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918242014	210	51.49	1	148	118	255	2.2e-16	54.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918242016	855	64.56	261	852	215	642	1.4e-112	371.2	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918242017	192	51.17	1	182	151	325	1.4e-32	107.6	COG0668	Small-conductance mechanosensitive channel	316
2918242018	228	36.26	4	183	23	146	8.8e-05	13.9	COG0668	Small-conductance mechanosensitive channel	316
2918242022	355	97.18	1	354	3	347	2.1e-78	257.8	COG1363	Putative aminopeptidase FrvX	355
2918242023	147	65.18	1	147	5	150	4.4e-44	144.7	COG2323	Uncharacterized membrane protein YcaP, DUF421 family	224
2918242025	84	44.17	1	77	89	160	5.8e-15	49.5	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
2918242029	304	98.01	9	303	2	296	7.1e-42	138.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242030	340	99.4	2	337	3	331	3.9e-60	198.3	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918242033	753	7.82	169	256	5	57	1.2e-89	33.7	COG1199	Rad3-related DNA helicase	654
2918242033	753	64.31	220	752	222	657	1.2e-89	260.5	COG1199	Rad3-related DNA helicase	654
2918242034	545	99.05	25	545	2	520	0.0e+00	697.4	COG0033	Phosphoglucomutase	524
2918242035	157	84.21	19	144	16	127	1.1e-23	77.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918242036	397	97.73	8	365	4	347	7.3e-122	400.3	COG1566	Multidrug resistance efflux pump	352
2918242037	511	38.9	263	507	9	157	2.8e-43	11.8	COG0477	MFS family permease	338
2918242037	511	71.28	11	269	7	279	2.8e-43	136.1	COG0477	MFS family permease	338
2918242038	49	14.93	1	49	227	266	1.3e-09	32.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918242039	685	63.45	105	548	140	389	2.3e-46	153.1	COG0642	Signal transduction histidine kinase	336
2918242040	469	98.68	1	469	3	452	0.0e+00	448.8	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918242041	469	97.98	30	445	3	391	4.2e-115	379	COG0348	Polyferredoxin	386
2918242043	176	64.6	19	176	6	151	8.7e-51	167.2	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
2918242045	299	66.34	5	296	2	275	4.7e-70	231	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918242046	133	96.97	6	129	1	128	4.4e-27	89.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918242047	292	87.12	168	292	11	125	5.8e-24	78.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918242048	395	92.37	1	386	2	364	1.9e-78	258.9	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918242049	293	98.01	12	292	1	295	3.9e-54	178.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242050	396	95.23	3	396	19	397	2.0e-106	350.3	COG1459	Type II secretory pathway, component PulF	397
2918242051	141	96.79	2	140	6	156	6.8e-32	105.5	COG2165	Type II secretory pathway, pseudopilin PulG	149
2918242052	198	51.49	39	192	131	286	2.4e-39	130.1	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2918242053	484	64.97	166	484	131	386	2.0e-42	140.7	COG0642	Signal transduction histidine kinase	336
2918242054	497	69.29	16	489	117	389	3.6e-43	142.3	COG0642	Signal transduction histidine kinase	336
2918242055	481	98.93	1	480	3	464	0.0e+00	506.2	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918242057	450	98.44	8	450	6	447	0.0e+00	506.5	COG2610	H+/gluconate symporter or related permease	442
2918242058	179	98.14	11	170	1	158	4.7e-58	189.6	COG3265	Gluconate kinase	161
2918242059	339	98.8	12	339	1	330	2.0e-89	294.5	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918242060	439	49.17	138	264	121	239	3.9e-25	38.7	COG2202	PAS domain	232
2918242060	439	56.61	3	142	103	239	3.9e-25	42.2	COG2202	PAS domain	232
2918242061	1090	24.72	391	456	13	56	1.4e-03	4.6	COG2410	Predicted nuclease (RNAse H fold)	178
2918242061	1090	30.34	330	394	120	173	1.4e-03	2.3	COG2410	Predicted nuclease (RNAse H fold)	178
2918242061	1090	30.56	6	216	62	153	7.2e-06	17.6	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
2918242061	1090	78.93	452	829	78	388	7.1e-70	231.1	COG0642	Signal transduction histidine kinase	336
2918242061	1090	83.2	971	1090	3	106	7.8e-10	33.8	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918242062	204	98.1	1	204	2	208	6.1e-52	170.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918242063	80	90.48	1	80	1	76	2.3e-34	112.1	COG3813	Uncharacterized protein	84
2918242064	250	98.04	1	250	3	252	1.2e-106	350	COG2875	Precorrin-4 methylase	254
2918242065	146	38.68	1	144	195	317	7.5e-18	59.3	COG2073	Cobalamin biosynthesis protein CbiG	298
2918242066	229	97.5	1	229	3	236	2.2e-93	306.6	COG5446	Uncharacterized membrane protein, predicted cobalt tansporter CbtA	233
2918242070	355	99.39	7	355	1	324	2.8e-98	323.7	COG0523	GTPase, G3E family	323
2918242071	1253	88.66	10	1253	14	1272	0.0e+00	1309.2	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
2918242072	337	12.53	1	61	13	65	2.1e-117	68	COG1239	Mg-chelatase subunit ChlI	423
2918242072	337	58.63	57	318	102	349	2.1e-117	319.5	COG1239	Mg-chelatase subunit ChlI	423
2918242073	215	77.74	2	214	48	260	4.4e-41	133.8	COG1240	Mg-chelatase subunit ChlD	261
2918242075	441	97.43	6	441	5	459	0.0e+00	462.3	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918242077	658	23.82	136	253	99	194	2.0e-28	23.7	COG3391	DNA-binding beta-propeller fold protein YncE	381
2918242077	658	44.42	233	478	77	255	2.0e-28	68.7	COG3391	DNA-binding beta-propeller fold protein YncE	381
2918242078	224	95.71	3	200	7	207	1.3e-31	104.1	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
2918242079	223	95.24	13	219	8	207	6.4e-24	78.9	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
2918242080	506	90.16	103	486	10	339	7.1e-20	62.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918242082	176	50.43	2	146	2	118	9.9e-26	84.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918242083	575	82.87	75	573	86	506	0.0e+00	541.7	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2918242084	260	69.23	34	130	16	87	4.0e-04	14.4	COG3492	Uncharacterized protein	104
2918242085	180	77.88	1	179	22	183	6.3e-05	16.8	COG3166	Tfp pilus assembly protein PilN	206
2918242086	184	60.19	19	183	59	185	2.1e-08	28.5	COG3167	Tfp pilus assembly protein PilO	211
2918242088	630	18.51	161	304	27	140	3.2e-64	29.5	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
2918242088	630	44.81	294	597	302	577	3.2e-64	186.4	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
2918242089	157	88.46	1	157	3	140	2.6e-18	61.5	COG2165	Type II secretory pathway, pseudopilin PulG	149
2918242090	124	50	1	119	4	81	8.4e-22	72.8	COG2165	Type II secretory pathway, pseudopilin PulG	149
2918242091	175	75.64	1	137	8	125	1.5e-10	36.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
2918242094	278	87.84	2	271	22	245	8.3e-50	163.9	COG1462	Curli biogenesis system outer membrane secretion channel CsgG	252
2918242096	219	94.5	5	208	12	200	1.7e-55	182.5	COG3145	Alkylated DNA repair dioxygenase AlkB	194
2918242103	191	94.85	5	191	5	188	1.5e-47	155.9	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
2918242104	1040	99.7	1	1024	3	1013	0.0e+00	1174.3	COG0841	Multidrug efflux pump subunit AcrB	1009
2918242105	389	98.21	5	381	6	388	1.4e-69	229.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918242106	233	98.28	2	229	2	229	3.4e-84	276.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918242107	432	83.5	2	432	59	387	1.2e-55	183.4	COG0642	Signal transduction histidine kinase	336
2918242108	143	91.95	1	142	7	143	6.1e-49	160.1	COG4125	Uncharacterized membrane protein	149
2918242110	520	99.42	14	355	3	346	0.0e+00	436.1	COG1171	Threonine dehydratase	347
2918242111	382	99.47	2	382	3	379	0.0e+00	465.8	COG1454	Alcohol dehydrogenase, class IV	377
2918242113	155	97.81	12	140	2	135	3.2e-35	115.6	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2918242114	539	90.4	32	516	38	470	5.9e-107	352.3	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918242115	729	66.67	258	728	201	642	3.4e-114	376.4	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918242115	729	79.54	3	276	21	261	7.6e-46	149.4	COG3452	Extracellular (periplasmic) sensor domain CHASE (specificity unknown)	297
2918242120	185	72.29	6	185	33	212	6.5e-36	118.2	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918242122	521	96.77	2	455	14	463	6.6e-32	105.3	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918242123	267	72.03	30	267	42	247	1.4e-20	67.9	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918242124	320	98.18	1	320	1	323	0.0e+00	432.9	COG1087	UDP-glucose 4-epimerase	329
2918242126	508	78.32	141	504	89	424	1.1e-11	38.9	COG3307	O-antigen ligase	424
2918242127	458	89.83	11	458	11	443	1.9e-26	87.1	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2918242129	488	23.94	9	134	6	141	1.3e-38	51.9	COG2303	Choline dehydrogenase or related flavoprotein	542
2918242129	488	62.68	124	486	203	558	1.3e-38	76.4	COG2303	Choline dehydrogenase or related flavoprotein	542
2918242130	197	64.21	8	156	63	184	1.8e-30	100.4	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918242131	318	90.73	3	304	7	290	1.4e-49	163.1	COG1216	Glycosyltransferase, GT2 family	305
2918242132	183	76.53	3	181	32	181	6.8e-44	143.9	COG1045	Serine acetyltransferase	194
2918242133	326	28.69	3	278	6	108	2.7e-10	35.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918242134	991	84.05	6	292	46	298	2.1e-46	152.2	COG2990	Uncharacterized protein VirK/YbjX	300
2918242134	991	91.69	575	987	4	378	4.8e-25	81.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918242135	400	77.75	2	400	88	405	5.4e-43	142.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918242136	396	74.85	5	388	61	438	4.8e-19	62.5	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2918242137	256	86.96	8	246	29	248	2.2e-44	145.7	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
2918242138	474	96.44	244	474	4	220	3.1e-79	259.4	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2918242139	313	97.01	9	306	5	296	1.7e-60	199.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242140	458	26.18	4	93	52	123	8.9e-121	10.8	COG1760	L-serine deaminase	262
2918242140	458	99.64	171	454	1	274	8.9e-121	384.1	COG1760	L-serine deaminase	262
2918242141	435	98.56	20	435	4	413	2.8e-116	383	COG0814	Amino acid permease	415
2918242143	127	99.19	1	124	1	122	1.8e-30	100.1	COG4737	Uncharacterized protein	123
2918242144	101	90.38	1	101	10	103	9.1e-29	94.1	COG2944	DNA-binding transcriptional regulator YiaG, XRE-type HTH domain	104
2918242145	431	98.45	27	412	4	385	2.0e-76	252.1	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918242146	362	96.03	1	362	15	377	7.1e-112	368.6	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918242147	452	98.65	4	451	5	444	0.0e+00	435.6	COG0174	Glutamine synthetase	443
2918242148	309	79.55	169	303	21	125	2.4e-16	53.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918242149	395	95.19	10	395	15	390	5.3e-110	362	COG2814	Predicted arabinose efflux permease, MFS family	394
2918242150	753	92.21	82	753	30	597	1.4e-126	416.3	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
2918242153	344	71.63	180	344	39	187	8.7e-05	15.3	COG3166	Tfp pilus assembly protein PilN	206
2918242154	237	18.83	107	184	171	231	1.7e-17	18	COG3156	Type II secretory pathway, component PulK	323
2918242154	237	33.64	1	120	4	112	1.7e-17	42.1	COG3156	Type II secretory pathway, component PulK	323
2918242155	201	54.49	1	177	5	89	4.8e-13	43.6	COG2165	Type II secretory pathway, pseudopilin PulG	149
2918242156	120	51.28	1	115	4	83	5.0e-11	37.8	COG2165	Type II secretory pathway, pseudopilin PulG	149
2918242157	146	83.97	5	134	6	136	3.0e-12	41.6	COG2165	Type II secretory pathway, pseudopilin PulG	149
2918242158	140	98.08	5	139	4	156	3.2e-19	64.4	COG2165	Type II secretory pathway, pseudopilin PulG	149
2918242159	399	99.25	1	399	1	395	1.6e-111	367.3	COG1459	Type II secretory pathway, component PulF	397
2918242160	505	96.85	8	504	16	507	0.0e+00	554.7	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2918242162	896	84.17	14	409	28	378	1.2e-57	189.1	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2918242163	213	96.65	13	213	4	205	7.2e-22	73.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918242164	428	90.22	6	426	37	451	6.0e-36	118	COG0534	Na+-driven multidrug efflux pump	455
2918242165	122	26.52	3	89	38	85	2.6e-03	11.5	COG1791	Acireductone dioxygenase (methionine salvage), cupin superfamily	181
2918242166	575	84.77	161	573	56	389	7.8e-52	171.8	COG0642	Signal transduction histidine kinase	336
2918242167	448	97.86	1	448	5	461	0.0e+00	515.6	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918242168	440	87.7	20	390	4	324	5.3e-45	148.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918242169	444	92.35	30	410	5	342	1.6e-26	87.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918242170	299	97.34	1	298	4	296	1.4e-70	232.6	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918242171	319	94.74	2	311	12	317	5.4e-48	158.2	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918242172	256	97.24	1	247	3	249	2.5e-74	244.1	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918242173	215	89.87	1	215	4	216	7.7e-64	209.5	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918242174	384	99.21	3	384	3	378	7.3e-120	394.6	COG1454	Alcohol dehydrogenase, class IV	377
2918242175	384	99.47	2	384	3	379	7.9e-121	397.8	COG1454	Alcohol dehydrogenase, class IV	377
2918242177	244	78.95	1	207	2	166	8.7e-26	84.9	COG0406	Broad specificity phosphatase PhoE	208
2918242181	423	19.03	21	107	18	84	6.1e-22	12.6	COG1566	Multidrug resistance efflux pump	352
2918242181	423	60.8	126	379	83	296	6.1e-22	62.2	COG1566	Multidrug resistance efflux pump	352
2918242182	715	97.61	13	711	3	696	0.0e+00	726.2	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918242183	471	91.96	12	469	24	446	5.9e-70	230.7	COG1538	Outer membrane protein TolC	457
2918242184	51	39.36	2	51	48	84	6.7e-01	5	COG1826	Sec-independent protein translocase protein TatA	94
2918242186	355	56.84	2	351	24	368	5.0e-74	244.1	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
2918242188	680	93.25	2	578	23	561	0.0e+00	554.7	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2918242193	518	20.4	412	511	208	279	1.6e-77	5.5	COG3515	Predicted component of the type VI protein secretion system	346
2918242193	518	99.72	3	415	2	353	1.6e-77	254.6	COG3515	Predicted component of the type VI protein secretion system	346
2918242194	167	95.86	1	166	6	167	3.6e-55	180.6	COG3516	Predicted component of the type VI protein secretion system	169
2918242195	491	97.58	1	491	10	492	0.0e+00	734.9	COG3517	Predicted component of the type VI protein secretion system	495
2918242196	135	89.81	2	135	14	154	2.9e-35	115.5	COG3518	Predicted component of the type VI protein secretion system	157
2918242197	595	99.36	1	595	5	621	0.0e+00	634.7	COG3519	Type VI protein secretion system component VasA	621
2918242198	335	98.51	1	335	1	330	7.9e-104	341.9	COG3520	Predicted component of the type VI protein secretion system	335
2918242199	866	97.52	12	864	3	787	0.0e+00	888.5	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918242200	505	93.27	3	501	34	546	0.0e+00	490.1	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2918242202	396	97.69	1	390	8	429	1.0e-85	279	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
2918242203	168	92.55	1	165	5	153	1.8e-44	145.6	COG3521	Predicted component of the type VI protein secretion system	159
2918242204	443	99.78	1	443	2	446	0.0e+00	533.3	COG3522	Predicted component of the type VI protein secretion system	446
2918242205	288	98.86	17	284	2	262	6.5e-87	285.8	COG3455	Type VI protein secretion system component VasF	262
2918242206	1174	99.41	2	1174	7	1190	0.0e+00	1043.7	COG3523	Type VI protein secretion system component VasK	1188
2918242207	202	77.21	1	202	49	258	1.8e-48	159.7	COG0631	Serine/threonine protein phosphatase PrpC	262
2918242208	245	57.02	1	243	41	308	6.5e-35	115.7	COG0515	Serine/threonine protein kinase	384
2918242209	202	72.6	2	201	2	152	1.9e-15	51.5	COG0125	Thymidylate kinase	208
2918242210	82	89.55	1	61	2	61	9.2e-12	39.3	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2918242211	57	13.42	1	56	341	393	7.3e-05	16	COG2814	Predicted arabinose efflux permease, MFS family	394
2918242215	146	26.34	10	142	5	127	6.7e-14	45.8	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918242216	138	80.14	1	128	5	117	4.3e-41	134.3	COG5478	Low affinity Fe/Cu permease	141
2918242217	704	71.57	211	566	107	388	1.7e-53	176.4	COG0642	Signal transduction histidine kinase	336
2918242218	154	22.22	72	148	105	142	1.2e-08	15.1	COG5592	Hemerythrin superfamily protein	171
2918242218	154	36.26	1	82	71	132	1.2e-08	19.1	COG5592	Hemerythrin superfamily protein	171
2918242219	615	95.19	24	600	23	616	8.4e-61	197.8	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
2918242221	147	65.18	1	147	5	150	2.7e-44	145.4	COG2323	Uncharacterized membrane protein YcaP, DUF421 family	224
2918242223	89	42.94	1	85	9	78	2.6e-21	70.2	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
2918242224	285	98.88	38	283	2	266	1.5e-66	219	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918242225	441	90.67	120	380	3	245	3.0e-48	159	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918242226	77	31.1	1	76	34	112	1.6e-03	12	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2918242229	93	96.74	1	92	1	89	4.9e-16	53.5	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
2918242230	436	50.91	232	427	4	198	1.4e-37	22.9	COG0477	MFS family permease	338
2918242230	436	63.19	8	269	4	245	1.4e-37	106.5	COG0477	MFS family permease	338
2918242231	259	98.51	4	253	3	266	1.3e-62	206.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918242232	297	92.81	6	283	4	261	2.0e-32	107	COG1082	Sugar phosphate isomerase/epimerase	274
2918242233	306	98.67	6	305	2	298	7.6e-57	187.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242234	353	92.82	1	347	25	373	1.3e-82	272.3	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918242235	316	97.76	1	255	6	267	9.0e-63	206.4	COG1018	Ferredoxin-NADP reductase	266
2918242236	237	87.07	1	224	19	220	8.8e-52	170.1	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918242237	445	52.48	253	443	2	202	4.0e-36	24.4	COG0477	MFS family permease	338
2918242237	445	74.93	15	294	8	294	4.0e-36	102.7	COG0477	MFS family permease	338
2918242238	345	79.58	14	343	68	332	9.7e-67	220	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918242239	554	96.93	22	546	4	476	1.2e-106	352.4	COG3119	Arylsulfatase A or related enzyme	475
2918242241	410	52.48	215	406	3	203	4.2e-37	30.1	COG0477	MFS family permease	338
2918242241	410	53	9	215	8	210	4.2e-37	98.7	COG0477	MFS family permease	338
2918242243	276	95.47	6	270	5	257	2.1e-65	215	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918242244	482	98.96	4	478	3	476	0.0e+00	495.3	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918242245	619	84.15	40	584	11	488	9.1e-57	186.9	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918242246	415	98.48	12	411	6	393	1.7e-85	281.8	COG0183	Acetyl-CoA acetyltransferase	392
2918242247	582	96.24	25	457	11	394	6.8e-87	285.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918242248	154	90.98	28	154	6	126	1.5e-26	87.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918242255	79	31.49	1	74	19	75	3.6e-03	11.5	COG1791	Acireductone dioxygenase (methionine salvage), cupin superfamily	181
2918242256	125	27.69	87	125	4	39	1.5e-08	14	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918242256	125	61.54	1	96	33	112	1.5e-08	15.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918242257	150	62.22	2	142	50	161	1.1e-03	13.5	COG4474	Uncharacterized SPBc2 prophage-derived protein YoqJ	180
2918242261	749	62.96	515	636	23	90	5.6e-02	6.3	COG2811	Archaeal/vacuolar-type H+-ATPase subunit H	108
2918242263	319	65.4	91	316	104	309	1.8e-14	45	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2918242265	135	53.85	1	134	66	184	1.1e-29	98.4	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2918242267	420	77.82	1	419	117	558	1.5e-42	140.4	COG2303	Choline dehydrogenase or related flavoprotein	542
2918242272	1103	98.37	3	1095	12	1097	0.0e+00	557.7	COG4913	Uncharacterized protein YPO0396	1104
2918242273	386	99.48	1	384	1	384	2.2e-96	317.4	COG4924	Uncharacterized protein	386
2918242277	223	78.47	10	191	3	166	4.5e-24	79.5	COG0406	Broad specificity phosphatase PhoE	208
2918242280	513	97.89	1	510	4	559	1.0e-77	255.3	COG2303	Choline dehydrogenase or related flavoprotein	542
2918242281	330	98.86	1	330	4	350	2.2e-81	268.4	COG0673	Predicted dehydrogenase	342
2918242282	432	96.22	12	431	10	416	6.7e-108	355.2	COG0738	Fucose permease	422
2918242283	289	80.3	157	287	20	125	4.4e-23	75.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918242287	145	24.22	23	136	149	218	1.3e-04	15.7	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
2918242288	146	26.98	10	145	5	130	2.6e-14	47.2	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918242290	154	83.07	1	153	7	163	2.2e-09	27.4	COG3945	Hemerythrin-like domain	189
2918242291	605	95.03	24	599	23	615	3.5e-61	200	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
2918242293	147	65.18	1	147	5	150	2.1e-44	145.8	COG2323	Uncharacterized membrane protein YcaP, DUF421 family	224
2918242295	167	90.8	4	160	13	160	1.6e-42	139.1	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
2918242297	285	98.88	38	283	2	266	1.9e-66	218.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918242300	179	96.94	6	179	3	192	2.9e-47	155.5	COG0693	Putative intracellular protease/amidase	188
2918242301	441	94.03	120	410	3	254	1.4e-50	166.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918242302	77	31.1	1	76	34	112	1.6e-03	12	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2918242303	400	100	1	388	1	353	5.3e-109	358.5	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918242304	201	50.87	17	177	3	149	3.0e-28	93.2	COG5483	Uncharacterized conserved protein, DUF488 family	289
2918242307	61	7.64	2	60	597	651	1.3e-11	38.3	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
2918242308	115	62.31	6	109	2	82	1.9e-09	32.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918242309	508	97.55	93	254	5	163	7.9e-40	130.7	COG3436	Transposase	157
2918242310	103	54.6	4	102	40	128	1.7e-15	51.4	COG3436	Transposase	157
2918242311	110	52.14	1	91	4	64	1.0e-15	52.6	COG2963	Transposase and inactivated derivatives	116
2918242315	117	80	8	117	10	105	6.3e-37	120.2	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2918242316	248	91.94	1	209	2	195	8.4e-42	137.2	COG2085	Predicted dinucleotide-binding enzyme	211
2918242320	395	95.44	13	395	15	391	3.7e-107	352.6	COG2814	Predicted arabinose efflux permease, MFS family	394
2918242321	406	93.3	1	394	15	362	1.3e-85	281.8	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918242322	213	86.72	1	213	24	232	1.4e-52	173	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918242323	447	94.99	4	447	23	439	0.0e+00	532.6	COG3659	Carbohydrate-selective porin OprB	439
2918242324	813	99.61	21	811	4	773	0.0e+00	793.5	COG4993	Glucose dehydrogenase	773
2918242325	332	94.19	8	328	4	311	4.3e-34	112.1	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918242326	478	38.9	307	472	55	203	1.1e-37	9.9	COG0477	MFS family permease	338
2918242326	478	84.6	25	335	7	330	1.1e-37	121.9	COG0477	MFS family permease	338
2918242327	264	97.39	6	262	4	264	8.2e-52	170.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918242328	373	94.02	1	369	21	350	5.1e-73	240.8	COG0673	Predicted dehydrogenase	342
2918242329	309	98.92	14	304	2	276	4.7e-50	164.9	COG1082	Sugar phosphate isomerase/epimerase	274
2918242330	269	98.43	1	254	4	254	1.1e-81	268.3	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
2918242331	616	99.68	2	615	2	617	0.0e+00	778.7	COG3962	TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism	617
2918242332	251	99.63	1	247	1	267	5.7e-60	197.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918242333	278	98.21	6	274	5	279	8.4e-49	160.9	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2918242335	314	97.34	10	310	5	297	5.0e-60	198	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242336	507	99.16	11	495	3	477	0.0e+00	499.8	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918242337	299	97.01	3	299	2	293	7.1e-47	155	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242338	287	84.25	5	133	3	125	6.4e-18	29.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918242338	287	98.63	136	248	2	145	6.4e-18	29.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918242339	233	93.3	7	224	12	220	5.0e-25	82.7	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2918242340	472	96.03	1	472	16	475	0.0e+00	520.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918242341	260	98.48	1	260	3	262	1.3e-89	294.4	COG3971	2-keto-4-pentenoate hydratase	264
2918242342	267	98.86	2	264	2	262	5.3e-78	256.2	COG3971	2-keto-4-pentenoate hydratase	264
2918242343	66	95.65	1	66	1	66	6.6e-18	58.7	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918242344	311	97.42	1	311	1	302	0.0e+00	526.4	COG4569	Acetaldehyde dehydrogenase (acetylating)	310
2918242345	339	81.6	5	338	1	337	2.1e-65	215.7	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918242346	449	49.87	244	449	5	195	1.3e-42	38.4	COG0477	MFS family permease	338
2918242346	449	54.31	19	249	8	215	1.3e-42	108.2	COG0477	MFS family permease	338
2918242348	52	13.58	4	52	249	289	4.4e-04	13.9	COG3285	Eukaryotic-type DNA primase	299
2918242349	304	80.3	149	304	20	125	5.0e-34	110.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918242350	329	97.81	1	316	1	313	1.2e-101	334.2	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918242351	103	74.75	2	88	5	78	1.2e-10	35.6	COG1359	Quinol monooxygenase YgiN	100
2918242352	96	26.58	11	95	1	80	1.2e-20	68.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242353	1060	99.61	4	1045	4	1013	0.0e+00	809.5	COG0841	Multidrug efflux pump subunit AcrB	1009
2918242354	387	97.18	8	383	8	386	6.7e-43	141.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918242355	231	97.16	26	231	3	207	9.4e-47	153.4	COG2085	Predicted dinucleotide-binding enzyme	211
2918242356	247	61.97	4	124	7	94	1.9e-14	47.1	COG0727	Fe-S-cluster containining protein	132
2918242357	255	76.41	1	235	65	294	1.3e-34	114.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242358	176	94.66	39	168	7	130	2.4e-28	93	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918242359	221	96.15	64	218	3	152	8.9e-64	208.1	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918242360	327	98.25	1	327	1	281	1.1e-90	298.5	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2918242361	736	99.06	1	736	3	740	0.0e+00	595.3	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918242362	322	94.02	6	322	3	285	5.9e-70	230.4	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2918242363	260	80.65	147	260	23	122	8.7e-51	85.8	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918242363	260	84.68	10	132	17	121	8.7e-51	78.2	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918242364	352	98.24	1	345	6	340	1.1e-121	400.3	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2918242365	300	95.68	6	299	5	292	1.9e-73	242.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242366	335	95.62	1	317	1	306	1.3e-99	327.5	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918242367	177	47.26	1	175	22	202	1.3e-02	9.5	COG0477	MFS family permease	338
2918242368	217	52.74	16	212	5	206	2.2e-35	116.8	COG0477	MFS family permease	338
2918242369	327	97.81	1	314	1	313	1.2e-101	334.1	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918242370	221	70.76	2	221	86	298	2.6e-39	130.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242371	273	97.01	1	265	7	266	3.4e-29	96.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918242372	196	95.42	39	195	2	147	6.8e-16	53.3	COG0716	Flavodoxin	151
2918242374	63	38.26	2	63	92	148	6.0e-10	33.7	COG5642	Uncharacterized conserved protein, DUF2384 family	149
2918242376	313	70.45	6	305	77	312	1.3e-07	25	COG0582	Integrase	309
2918242377	256	20.38	2	253	684	921	5.1e-06	18	COG1196	Chromosome segregation ATPase	1163
2918242378	327	98.67	29	325	1	297	2.3e-71	235.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242379	250	99.25	3	249	2	267	1.2e-68	226	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918242384	302	98.01	3	299	3	297	1.6e-67	222.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242385	329	99.4	2	329	2	330	7.9e-84	276.2	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918242386	402	96.71	14	402	11	392	3.5e-106	349.4	COG2814	Predicted arabinose efflux permease, MFS family	394
2918242387	284	83.21	7	256	4	226	1.2e-40	134.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918242388	374	89.42	102	371	29	290	3.4e-50	165.1	COG1408	Predicted phosphohydrolase, MPP superfamily	284
2918242389	314	97.01	12	307	2	293	8.0e-69	227	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242390	100	92.78	1	100	5	94	1.8e-19	64.2	COG1669	Predicted nucleotidyltransferase	97
2918242393	147	9.45	2	31	20	43	1.4e-03	4.2	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2918242393	147	9.45	65	147	159	182	1.4e-03	7.3	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2918242395	231	73.15	32	230	64	251	7.9e-52	169.3	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
2918242396	187	92.72	2	179	4	194	1.9e-21	71.1	COG1335	Nicotinamidase-related amidase	205
2918242399	111	57.67	5	104	40	133	5.0e-15	49.6	COG3436	Transposase	157
2918242400	106	58.12	1	90	4	71	3.8e-15	50.7	COG2963	Transposase and inactivated derivatives	116
2918242403	43	41.67	2	39	4	38	1.2e-06	22.2	COG4118	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor	84
2918242405	297	96.68	4	293	7	297	1.0e-46	154.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242406	143	92.59	1	135	5	129	9.8e-24	78.3	COG3791	Uncharacterized conserved protein	133
2918242408	330	100	1	327	1	331	1.5e-86	285.1	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918242409	112	81.45	4	109	19	119	9.4e-26	84.8	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918242410	478	98.12	8	478	3	472	0.0e+00	544.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918242411	308	97.67	2	300	3	296	8.7e-68	223.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242412	202	21.07	145	197	103	153	2.1e-18	15.4	COG2202	PAS domain	232
2918242412	202	51.65	14	153	118	242	2.1e-18	49.5	COG2202	PAS domain	232
2918242414	136	54.62	6	123	2	72	4.0e-12	41.5	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918242421	534	19.41	6	168	22	67	3.6e-08	11.6	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
2918242421	534	26.16	264	358	144	205	3.6e-08	13	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
2918242422	355	7.75	3	66	22	73	1.1e-11	3.1	COG0210	Superfamily I DNA or RNA helicase	655
2918242422	355	10.13	96	190	196	263	1.1e-11	23.2	COG0210	Superfamily I DNA or RNA helicase	655
2918242422	355	10.13	259	352	567	634	1.1e-11	8.8	COG0210	Superfamily I DNA or RNA helicase	655
2918242427	363	31.69	100	358	121	210	4.5e-06	20.3	COG2801	Transposase InsO and inactivated derivatives	232
2918242431	114	34.62	15	97	2	46	1.9e-05	19.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918242432	448	93.29	1	445	11	469	3.0e-73	241.3	COG0531	Amino acid transporter	466
2918242434	95	38.55	2	77	13	81	4.1e-03	10.8	COG2042	Ribosome biogenesis protein Tsr3 (rRNA maturation)	179
2918242436	400	99.72	1	388	2	353	2.9e-107	352.6	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918242437	183	85.5	1	178	27	197	4.7e-33	109	COG0740	ATP-dependent protease ClpP, protease subunit	200
2918242438	305	96.99	2	303	2	259	2.1e-85	280.7	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
2918242439	261	97.67	14	261	5	255	4.7e-68	223.7	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918242440	400	81.03	1	380	65	457	2.8e-67	221.2	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918242441	319	94.75	3	311	12	318	4.5e-50	165	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2918242443	58	6.46	1	43	16	42	1.2e-01	5.7	COG2995	Uncharacterized paraquat-inducible protein A	418
2918242445	828	96.36	533	826	6	296	1.8e-96	316.5	COG3285	Eukaryotic-type DNA primase	299
2918242445	828	99.39	74	540	1	489	2.7e-111	366.9	COG1793	ATP-dependent DNA ligase	444
2918242446	347	62.41	47	324	125	373	5.1e-15	49.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918242447	251	86.99	32	250	10	223	7.1e-25	82.1	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
2918242448	199	41.96	3	186	56	175	7.5e-05	16.2	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2918242449	219	30.36	1	206	4	112	1.1e-10	36.7	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918242450	291	97.13	1	285	4	274	2.2e-93	306.6	COG1273	Non-homologous end joining protein Ku, dsDNA break repair	278
2918242451	171	42.82	1	170	203	360	9.5e-29	94.9	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
2918242452	185	48.24	3	183	3	180	1.6e-42	140.2	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
2918242453	317	74.91	8	312	4	218	2.2e-30	99.6	COG2890	Methylase of polypeptide chain release factors	280
2918242456	55	45.95	1	46	32	65	9.2e-10	33	COG3729	General stress protein YciG, contains tandem KGG domains	73
2918242457	422	16.9	8	106	27	112	1.7e-41	26	COG3202	ATP/ADP translocase	509
2918242457	422	66.21	110	418	148	484	1.7e-41	105.4	COG3202	ATP/ADP translocase	509
2918242458	302	95.62	31	302	3	308	1.3e-36	115.2	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918242459	292	78.42	2	292	70	356	1.6e-45	149.4	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
2918242460	301	87.04	1	295	35	316	1.7e-74	245.1	COG0385	Predicted Na+-dependent transporter	319
2918242461	166	37.01	3	140	131	234	2.4e-04	14.7	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
2918242462	235	96.02	1	229	9	225	3.0e-67	220.9	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
2918242463	264	99.23	4	260	1	257	9.6e-83	271.7	COG0708	Exonuclease III	261
2918242465	166	92.4	3	165	12	169	8.5e-31	101.5	COG3652	Predicted outer membrane protein	170
2918242468	334	29.93	35	331	333	616	2.1e-04	13.3	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2918242469	283	98.34	2	282	1	296	2.9e-46	152.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242470	331	97.5	1	327	1	312	1.0e-110	363.8	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918242471	276	98.31	1	276	4	293	2.9e-51	169.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918242472	759	66.97	263	750	195	638	1.2e-108	357.9	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918242473	316	77.91	2	310	53	313	1.0e-10	35.9	COG0582	Integrase	309
2918242474	570	79.1	1	276	1	212	1.8e-39	130.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918242474	570	95.47	281	568	15	309	2.4e-71	234.3	COG3386	Sugar lactone lactonase YvrE	307
2918242475	323	96.35	2	302	2	291	2.8e-59	195.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242476	611	97.99	1	609	1	537	0.0e+00	485.1	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2918242477	461	82.33	79	459	79	474	8.0e-56	183.1	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918242478	330	62.5	2	315	187	531	1.2e-12	39.9	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918242479	94	67.9	2	86	5	59	2.8e-08	27.9	COG0236	Acyl carrier protein	80
2918242480	135	79.71	1	61	1	55	1.8e-03	9	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918242481	580	12.28	459	552	76	117	4.3e-23	3.1	COG5029	Prenyltransferase, beta subunit	342
2918242481	580	22.51	12	102	157	233	4.3e-23	13.1	COG5029	Prenyltransferase, beta subunit	342
2918242481	580	23.1	218	361	106	184	4.3e-23	8.5	COG5029	Prenyltransferase, beta subunit	342
2918242481	580	26.02	368	488	83	171	4.3e-23	22.7	COG5029	Prenyltransferase, beta subunit	342
2918242481	580	36.55	90	239	93	217	4.3e-23	23.8	COG5029	Prenyltransferase, beta subunit	342
2918242482	438	78.77	52	415	62	406	2.6e-35	116	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
2918242483	396	95.44	1	387	10	386	1.9e-85	281	COG2814	Predicted arabinose efflux permease, MFS family	394
2918242484	379	99.47	1	378	1	376	0.0e+00	492.2	COG1929	Glycerate kinase	378
2918242485	365	98.94	2	364	2	373	3.0e-101	333.2	COG3835	Sugar diacid utilization regulator	376
2918242486	442	48.04	247	441	4	187	1.7e-28	15.3	COG0477	MFS family permease	338
2918242486	442	74.93	20	283	7	293	1.7e-28	89	COG0477	MFS family permease	338
2918242487	640	96.24	3	635	23	611	0.0e+00	609.1	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
2918242488	477	99.16	6	477	1	475	0.0e+00	536.5	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918242489	730	9.18	500	581	692	762	1.1e-93	30.2	COG4993	Glucose dehydrogenase	773
2918242489	730	61.06	11	508	148	619	1.1e-93	284	COG4993	Glucose dehydrogenase	773
2918242490	396	90.38	5	394	30	386	2.1e-27	89.8	COG2814	Predicted arabinose efflux permease, MFS family	394
2918242492	353	50.46	190	342	81	189	1.2e-09	27.8	COG0778	Nitroreductase	207
2918242493	335	97.81	1	320	1	313	4.1e-100	329.1	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918242495	362	82.23	1	200	3	164	5.2e-23	76	COG1988	Membrane-bound metal-dependent hydrolase YbcI, DUF457 family	190
2918242497	399	95.53	1	392	16	400	0.0e+00	445.1	COG3135	Predicted benzoate:H+ symporter BenE	402
2918242498	308	96.49	55	301	4	223	1.9e-41	136.2	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2918242499	96	97.96	1	96	1	96	1.8e-42	137.8	COG4829	Muconolactone delta-isomerase	98
2918242500	373	97.86	5	373	4	368	3.2e-74	244.1	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918242501	442	52.48	249	439	4	204	2.2e-39	28.9	COG0477	MFS family permease	338
2918242501	442	54.83	14	247	5	214	2.2e-39	107.1	COG0477	MFS family permease	338
2918242502	253	98.88	3	252	2	266	1.6e-60	199.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918242503	336	84.05	97	333	8	223	6.2e-56	183.3	COG0543	NAD(P)H-flavin reductase	252
2918242503	336	85.44	3	98	9	96	8.2e-16	51.1	COG0633	Ferredoxin	102
2918242504	162	98.17	1	162	4	164	2.0e-68	223.9	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
2918242505	452	96.81	16	445	3	366	2.2e-83	274.7	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918242507	318	77.27	194	318	23	124	4.8e-19	62.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918242508	351	96	23	344	8	319	9.5e-84	275.2	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918242509	342	97.38	6	338	6	302	3.3e-73	240.6	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
2918242510	316	94.85	5	293	7	282	2.8e-113	372.2	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
2918242511	386	98.71	4	386	4	386	0.0e+00	498	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
2918242512	294	16.56	217	293	231	281	2.5e-24	24.6	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918242512	294	47.4	60	227	16	161	2.5e-24	54	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918242514	263	97.68	7	260	7	259	3.3e-68	224	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2918242515	215	71.25	147	213	17	73	5.8e-12	38.2	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918242516	666	97.79	21	245	2	222	2.6e-81	266	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918242516	666	99.61	288	666	1	508	2.2e-82	272.1	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918242517	385	91.54	3	384	16	372	1.0e-51	170.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918242518	4834	72.97	1048	1122	14	67	2.2e-10	8.1	COG3433	Aryl carrier domain	74
2918242518	4834	75.68	2089	2161	14	69	2.2e-10	4	COG3433	Aryl carrier domain	74
2918242518	4834	75.68	4191	4263	15	70	2.2e-10	6.7	COG3433	Aryl carrier domain	74
2918242518	4834	81.08	3134	3201	6	65	2.2e-10	15.8	COG3433	Aryl carrier domain	74
2918242518	4834	93	4567	4823	2	240	1.2e-81	130.4	COG3319	Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase	257
2918242518	4834	97.67	4279	4548	1	251	1.2e-81	143.1	COG3319	Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase	257
2918242518	4834	99.07	314	956	7	648	0.0e+00	417.6	COG1020	Non-ribosomal peptide synthetase component F	642
2918242518	4834	99.07	1356	1996	3	644	0.0e+00	493.4	COG1020	Non-ribosomal peptide synthetase component F	642
2918242518	4834	99.07	2399	3047	3	644	0.0e+00	559.1	COG1020	Non-ribosomal peptide synthetase component F	642
2918242518	4834	99.23	3451	4101	3	645	0.0e+00	433.1	COG1020	Non-ribosomal peptide synthetase component F	642
2918242519	7459	71.62	4224	4292	9	61	2.7e-32	12.9	COG3433	Aryl carrier domain	74
2918242519	7459	72.97	1040	1109	8	61	2.7e-32	13.6	COG3433	Aryl carrier domain	74
2918242519	7459	77.03	2102	2172	8	64	2.7e-32	8.5	COG3433	Aryl carrier domain	74
2918242519	7459	78.38	6336	6407	10	67	2.7e-32	17.5	COG3433	Aryl carrier domain	74
2918242519	7459	79.73	5276	5346	5	63	2.7e-32	18.9	COG3433	Aryl carrier domain	74
2918242519	7459	81.08	7389	7455	3	62	2.7e-32	18.1	COG3433	Aryl carrier domain	74
2918242519	7459	90.54	3166	3238	4	70	2.7e-32	14.1	COG3433	Aryl carrier domain	74
2918242519	7459	98.77	3492	4138	5	644	0.0e+00	503.1	COG1020	Non-ribosomal peptide synthetase component F	642
2918242519	7459	99.23	4538	5183	6	648	0.0e+00	434.2	COG1020	Non-ribosomal peptide synthetase component F	642
2918242519	7459	99.23	6656	7302	2	644	0.0e+00	511.7	COG1020	Non-ribosomal peptide synthetase component F	642
2918242519	7459	99.38	2422	3076	3	646	0.0e+00	470.2	COG1020	Non-ribosomal peptide synthetase component F	642
2918242519	7459	99.54	1375	2015	4	648	0.0e+00	406.4	COG1020	Non-ribosomal peptide synthetase component F	642
2918242519	7459	99.85	312	953	2	648	0.0e+00	421.2	COG1020	Non-ribosomal peptide synthetase component F	642
2918242519	7459	99.85	5609	6249	2	648	0.0e+00	419.5	COG1020	Non-ribosomal peptide synthetase component F	642
2918242520	2124	63.51	2036	2099	14	60	1.8e-09	15.9	COG3433	Aryl carrier domain	74
2918242520	2124	77.03	962	1033	5	61	1.8e-09	12.6	COG3433	Aryl carrier domain	74
2918242520	2124	99.38	1298	1948	4	647	0.0e+00	443	COG1020	Non-ribosomal peptide synthetase component F	642
2918242520	2124	99.85	237	878	2	648	0.0e+00	402	COG1020	Non-ribosomal peptide synthetase component F	642
2918242521	260	72.5	187	259	17	74	1.9e-10	33.6	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918242522	470	98.04	10	470	4	454	4.3e-130	428.9	COG1538	Outer membrane protein TolC	457
2918242523	194	95	1	194	6	195	7.2e-40	131.3	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
2918242524	296	71.7	18	144	25	138	1.1e-16	13	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918242524	296	93.08	146	296	9	156	1.1e-16	46.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918242525	294	98.01	3	294	2	296	3.9e-62	205	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242526	461	95.2	4	461	20	475	0.0e+00	499.9	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918242528	292	97.01	11	292	2	293	3.3e-41	136.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242529	243	94.56	1	238	10	235	2.6e-51	168.6	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
2918242530	108	97.2	1	107	3	106	9.0e-27	87.8	COG4392	Branched-chain amino acid transport protein	107
2918242532	540	91.76	43	540	36	425	3.3e-104	343.7	COG0840	Methyl-accepting chemotaxis protein	408
2918242536	132	88.97	1	124	6	126	7.5e-05	15	COG3631	Ketosteroid isomerase-related protein	133
2918242538	390	84.7	20	376	3	312	5.1e-46	151.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918242539	289	97.01	1	286	6	297	5.2e-72	237	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918242540	826	94.74	2	306	16	321	2.2e-71	234.6	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918242540	826	98.31	331	570	4	236	0.0e+00	150.6	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918242540	826	99.16	587	822	2	236	0.0e+00	276.6	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918242541	416	88.44	3	399	23	397	2.9e-49	161.7	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918242542	231	92.24	1	222	12	225	9.9e-48	156.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918242543	519	97.43	1	517	14	544	3.8e-106	350.3	COG0405	Gamma-glutamyltranspeptidase	539
2918242545	159	98.7	5	159	3	154	2.9e-87	284.6	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
2918242546	549	84.07	28	355	9	330	7.6e-08	26.8	COG0477	MFS family permease	338
2918242547	374	92.61	21	374	15	340	3.9e-100	329.1	COG1566	Multidrug resistance efflux pump	352
2918242548	291	98.72	1	291	1	309	2.0e-54	179	COG0679	Predicted permease	311
2918242549	430	50.13	195	407	8	199	2.9e-20	42.6	COG0477	MFS family permease	338
2918242549	430	52.74	3	201	9	210	2.9e-20	30.2	COG0477	MFS family permease	338
2918242551	183	89.39	6	183	17	176	1.2e-40	133.3	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
2918242552	310	98.01	2	297	2	296	3.4e-67	221.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242554	230	98.67	4	230	2	224	5.7e-65	213.1	COG2384	tRNA A22 N-methylase	226
2918242555	126	89.71	2	126	13	134	6.6e-25	81.9	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918242556	694	93.84	8	692	46	791	3.2e-74	245.1	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918242557	734	98.93	3	734	4	740	0.0e+00	640.4	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918242558	330	98.95	1	326	1	283	6.9e-103	338.4	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2918242559	170	96.15	10	164	3	152	2.8e-67	219.5	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918242560	666	7.14	530	564	114	138	9.5e-98	4.4	COG0826	Collagenase-like protease, PrtC family	347
2918242560	666	86	3	342	5	305	9.5e-98	315.2	COG0826	Collagenase-like protease, PrtC family	347
2918242568	706	95.97	3	706	33	795	8.8e-121	399.3	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918242569	282	95	185	265	3	78	8.4e-20	64	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918242570	303	80.18	14	296	5	267	5.1e-57	187.5	COG0142	Geranylgeranyl pyrophosphate synthase	322
2918242571	348	93.63	2	346	13	350	4.4e-94	309.2	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2918242572	426	98.53	1	417	3	404	4.7e-42	138.3	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
2918242574	496	98.59	2	495	3	492	1.0e-107	355.4	COG1233	Phytoene dehydrogenase-related protein	487
2918242575	360	93.77	1	293	11	281	2.0e-58	191.8	COG1562	Phytoene/squalene synthetase	288
2918242577	356	99.25	7	336	3	265	3.5e-71	233.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918242578	383	98.5	2	383	2	394	0.0e+00	460.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918242581	366	96.3	12	358	11	348	0.0e+00	470.1	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
2918242582	93	30.46	1	93	170	268	6.8e-31	102.2	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918242583	617	97.21	7	601	11	568	3.1e-110	363.5	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2918242584	352	99.73	1	351	1	363	0.0e+00	579.3	COG4174	ABC-type microcin C transport system, permease component YejB	364
2918242585	338	98.24	1	338	4	338	0.0e+00	527.5	COG4239	ABC-type microcin C transport system, permease component YejE	341
2918242586	256	99.63	1	255	1	267	2.1e-70	231.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918242587	159	92.59	4	159	12	161	1.0e-67	220.9	COG4574	Serine protease inhibitor ecotin	162
2918242588	652	99.82	80	632	1	551	0.0e+00	506.7	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918242589	91	28.62	2	87	171	263	2.4e-25	83.7	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918242590	780	99.7	124	780	3	658	4.0e-49	161.5	COG3468	Type V secretory pathway, adhesin AidA	644
2918242591	207	99.52	1	207	1	207	1.6e-50	165.5	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918242592	272	75	73	272	27	125	1.9e-26	86.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918242593	206	97.6	1	204	3	205	5.5e-35	114.7	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918242595	247	88.13	1	236	3	247	1.7e-29	96.8	COG0388	Predicted amidohydrolase	274
2918242597	166	97.02	2	159	5	167	3.8e-54	177.9	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2918242602	648	95.12	1	364	10	379	1.3e-80	265.2	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918242607	156	73.44	14	156	30	123	2.2e-08	28.3	COG3755	Uncharacterized conserved protein YecT, DUF1311 family	127
2918242608	155	20.61	118	153	104	130	8.7e-07	18.3	COG5455	Periplasmic regulator RcnB of Ni and Co efflux	129
2918242608	155	37.4	9	101	33	81	8.7e-07	3.7	COG5455	Periplasmic regulator RcnB of Ni and Co efflux	129
2918242611	185	33.43	7	171	205	316	8.0e-11	36.6	COG0582	Integrase	309
2918242612	528	98.88	1	526	4	532	0.0e+00	625.7	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918242613	396	50.91	212	396	8	202	1.4e-18	23.2	COG0477	MFS family permease	338
2918242613	396	54.57	15	221	2	210	1.4e-18	43.7	COG0477	MFS family permease	338
2918242614	351	89.76	15	337	32	364	4.4e-40	131.7	COG4188	Predicted dienelactone hydrolase	365
2918242615	203	97.52	1	199	3	199	6.5e-67	219.1	COG1182	FMN-dependent NADH-azoreductase	202
2918242616	300	98.34	2	298	2	297	8.2e-66	217.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242617	119	97.48	6	119	1	116	1.0e-27	90.9	COG2315	Predicted DNA-binding protein with ?double-wing? structural motif, MmcQ/YjbR family	118
2918242618	137	88.3	44	135	6	88	3.1e-30	98.7	COG3326	Uncharacterized membrane protein YsdA, DUF1294 family	94
2918242619	276	99.27	1	267	1	271	8.4e-104	341	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
2918242620	544	81.88	129	544	78	425	3.7e-100	330.2	COG0840	Methyl-accepting chemotaxis protein	408
2918242621	188	84.23	1	188	27	213	8.4e-45	147.3	COG3201	Nicotinamide riboside transporter PnuC	222
2918242622	183	95.19	1	177	8	185	6.2e-50	163.8	COG3172	Nicotinamide riboside kinase	187
2918242626	226	96.06	14	226	7	201	1.2e-48	159	COG3271	Predicted double-glycine peptidase	201
2918242628	389	18.22	129	197	194	236	6.8e-05	7.8	COG3637	Opacity protein and related surface antigens	199
2918242628	389	22.46	260	364	180	232	6.8e-05	8.1	COG3637	Opacity protein and related surface antigens	199
2918242629	733	11.55	453	696	399	474	1.7e-28	5.8	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
2918242629	733	38.75	10	310	9	263	1.7e-28	22.2	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
2918242629	733	49.09	200	542	256	578	1.7e-28	77.4	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
2918242630	128	100	1	126	1	146	5.3e-11	38.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918242632	556	21.15	243	349	8	88	8.0e-38	21.7	COG0477	MFS family permease	338
2918242632	556	23.5	373	553	103	192	8.0e-38	10.5	COG0477	MFS family permease	338
2918242632	556	74.67	22	282	2	287	8.0e-38	101.6	COG0477	MFS family permease	338
2918242633	308	98.31	8	297	3	292	9.6e-31	101.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918242634	1629	18.59	1159	1356	154	232	1.7e-10	14.3	COG4886	Leucine-rich repeat (LRR) protein	394
2918242634	1629	27.76	939	1157	152	269	1.7e-10	17.4	COG4886	Leucine-rich repeat (LRR) protein	394
2918242635	822	11.92	692	794	551	630	8.6e-54	33.2	COG0210	Superfamily I DNA or RNA helicase	655
2918242635	822	13.56	125	263	4	94	8.6e-54	45.7	COG0210	Superfamily I DNA or RNA helicase	655
2918242635	822	26.38	457	700	174	350	8.6e-54	95.2	COG0210	Superfamily I DNA or RNA helicase	655
2918242636	232	87.14	1	232	3	246	2.9e-61	201.7	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2918242637	304	78	7	301	49	282	1.4e-30	100.7	COG4974	Site-specific recombinase XerD	300
2918242638	215	92.54	1	215	18	228	3.2e-51	168.7	COG4291	Uncharacterized membrane protein	228
2918242640	695	64.86	81	692	212	641	5.7e-116	381.9	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918242641	495	99.13	30	495	1	456	4.0e-124	409.1	COG1538	Outer membrane protein TolC	457
2918242642	1035	99.7	2	1015	2	1012	0.0e+00	1104.4	COG0841	Multidrug efflux pump subunit AcrB	1009
2918242643	1032	99.9	2	1017	1	1013	0.0e+00	1170.1	COG0841	Multidrug efflux pump subunit AcrB	1009
2918242644	422	97.44	3	392	6	385	6.8e-69	226.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918242645	166	100	1	158	1	158	4.7e-70	228.3	COG2077	Peroxiredoxin	158
2918242647	429	97.84	18	427	6	412	2.5e-116	382.9	COG0814	Amino acid permease	415
2918242648	398	99.75	1	397	1	395	0.0e+00	557.5	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
2918242649	341	96.28	7	341	4	339	1.1e-103	341.1	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
2918242650	290	98.58	1	279	2	279	6.5e-44	144.3	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918242651	250	96.11	2	250	5	276	5.9e-61	200.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918242652	239	97.83	10	237	4	228	2.2e-76	250.4	COG4215	ABC-type arginine transport system, permease component	230
2918242653	236	97.37	11	236	5	226	1.8e-77	254	COG4160	ABC-type arginine/histidine transport system, permease component	228
2918242654	414	97.42	1	414	5	382	1.8e-63	207.9	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918242655	260	99.17	19	259	2	241	2.1e-110	361.8	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918242656	270	98.36	13	260	3	242	3.8e-68	223.8	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
2918242657	303	96.66	10	303	6	294	4.1e-69	226.8	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918242658	455	91.33	2	434	25	435	3.9e-39	128.9	COG2271	Sugar phosphate permease	448
2918242659	517	19.1	4	92	145	220	0.0e+00	1.4	COG2721	Altronate dehydratase	381
2918242659	517	98.49	110	517	6	397	0.0e+00	499.3	COG2721	Altronate dehydratase	381
2918242660	526	98.96	6	500	2	475	3.0e-70	231.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918242662	249	97.93	7	247	3	238	2.1e-61	201.6	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918242664	310	98.34	8	304	4	299	4.8e-64	211.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242665	324	99.09	2	324	3	330	8.9e-81	266	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918242666	404	36.97	236	398	79	156	6.2e-27	19.5	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
2918242666	404	87.68	12	217	25	209	6.2e-27	75.4	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
2918242667	232	51.23	5	215	58	182	5.9e-13	42.7	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2918242669	326	94.33	5	324	5	320	1.7e-55	182.7	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918242670	454	97.67	10	424	8	342	3.8e-90	296.7	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918242671	278	99.24	3	273	2	263	3.6e-128	420.9	COG3257	Uncharacterized protein, possibly involved in glyoxylate utilization	264
2918242674	295	99.64	1	284	1	279	1.8e-89	294.3	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2918242675	440	96.21	15	419	13	342	5.9e-85	279.5	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918242676	330	95.22	1	315	9	327	2.3e-51	169.2	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918242677	202	99.48	1	195	2	191	2.9e-65	214.2	COG5553	Predicted metal-dependent enzyme of the double-stranded beta helix superfamily	191
2918242678	529	76.32	264	366	12	98	1.9e-51	34.2	COG0607	Rhodanese-related sulfurtransferase	110
2918242678	529	84.21	6	108	14	109	1.9e-51	51.9	COG0607	Rhodanese-related sulfurtransferase	110
2918242678	529	90.35	127	234	9	111	1.9e-51	49.5	COG0607	Rhodanese-related sulfurtransferase	110
2918242678	529	94.74	372	477	5	112	1.9e-51	27.4	COG0607	Rhodanese-related sulfurtransferase	110
2918242679	171	91.8	1	171	16	183	2.6e-59	194.5	COG2032	Cu/Zn superoxide dismutase	179
2918242680	798	96.35	90	798	27	792	1.0e-63	210.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918242681	315	98.14	2	311	7	323	5.3e-83	272.8	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918242682	171	86.02	2	169	14	173	5.2e-33	108.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918242683	207	95.96	1	203	6	195	7.4e-79	258	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
2918242684	224	99.13	1	224	3	229	3.9e-62	204.6	COG0830	Urease accessory protein UreF	229
2918242685	181	91.54	1	181	14	197	3.7e-27	89.3	COG2370	Hydrogenase/urease accessory protein HupE	201
2918242686	167	99.36	1	155	2	156	4.3e-45	147.3	COG2371	Urease accessory protein UreE	155
2918242687	567	100	1	567	1	569	0.0e+00	1048.6	COG0804	Urease alpha subunit	568
2918242689	105	96.23	1	104	1	102	2.1e-50	163.4	COG0832	Urease beta subunit	106
2918242690	100	98	1	100	2	99	3.3e-52	169.2	COG0831	Urease gamma subunit	100
2918242691	277	98.53	12	275	5	272	2.6e-67	221.3	COG0829	Urease accessory protein UreH	269
2918242693	526	94.21	4	524	2	505	6.3e-105	345.4	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918242694	338	98.6	26	327	4	284	6.8e-91	299.3	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2918242695	226	98.71	2	226	2	230	9.8e-76	248.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918242696	460	92.39	69	460	25	388	6.7e-51	168.2	COG0642	Signal transduction histidine kinase	336
2918242697	460	99.35	1	459	2	463	0.0e+00	616.7	COG0215	Cysteinyl-tRNA synthetase	464
2918242698	567	99.58	33	544	3	480	0.0e+00	477.2	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2918242699	166	98.09	3	166	2	155	3.8e-51	167.5	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
2918242700	240	98.76	3	240	2	239	1.1e-69	228.7	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
2918242701	770	48.14	6	354	12	386	9.7e-96	203.5	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
2918242701	770	60.72	330	761	303	775	9.7e-96	116.9	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
2918242703	62	21.88	1	62	191	246	1.3e-05	19	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918242705	451	97.96	13	446	4	388	0.0e+00	433	COG3004	Na+/H+ antiporter NhaA	390
2918242706	331	99.4	1	330	2	331	7.7e-113	371.4	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918242707	227	19.77	14	62	3	37	1.7e-39	16.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918242707	227	77.97	71	222	39	176	1.7e-39	118.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918242708	427	99.74	47	425	1	378	0.0e+00	499.4	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918242709	291	90.68	1	291	28	319	4.1e-97	319.4	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
2918242710	674	95.88	2	673	24	652	0.0e+00	728.2	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
2918242711	142	82.05	1	133	27	154	1.6e-33	109.9	COG4729	Uncharacterized protein	156
2918242712	1223	99.48	1	1223	8	1334	0.0e+00	690.6	COG2911	Autotransporter translocation and assembly factor TamB	1278
2918242713	583	95.85	7	583	26	603	0.0e+00	519.5	COG0729	Outer membrane translocation and assembly module TamA	594
2918242714	216	63.58	11	212	51	153	2.1e-11	36.8	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918242715	270	99.23	1	270	1	257	6.8e-82	268.9	COG0708	Exonuclease III	261
2918242716	335	95.98	1	327	11	320	3.7e-80	263.4	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918242717	439	100	1	439	1	445	0.0e+00	636.2	COG2056	Predicted histidine transporter YuiF, NhaC family	444
2918242718	714	81.88	230	714	78	425	1.8e-114	377.2	COG0840	Methyl-accepting chemotaxis protein	408
2918242720	305	97.44	1	305	4	308	3.7e-54	178.2	COG0679	Predicted permease	311
2918242721	203	53.85	13	200	110	242	7.6e-29	95.4	COG3773	Cell wall hydrolase CwlJ, involved in spore germination	249
2918242722	805	99.35	13	805	5	772	0.0e+00	958.2	COG4993	Glucose dehydrogenase	773
2918242723	426	96.58	2	426	16	439	2.2e-69	228.4	COG3659	Carbohydrate-selective porin OprB	439
2918242724	384	95.93	1	384	17	417	1.6e-80	265.6	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918242725	225	84.91	1	225	1	225	2.5e-75	247.6	COG3342	Uncharacterized conserved protein, Ntn-hydrolase superfamily	265
2918242726	440	94.62	4	435	10	431	6.4e-65	214.2	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2918242727	138	86.76	7	136	18	135	2.0e-25	83.5	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918242728	301	98.34	4	301	2	297	9.8e-61	200.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242729	391	48.56	206	390	9	194	2.4e-11	9.2	COG0477	MFS family permease	338
2918242729	391	82.25	6	270	8	322	2.4e-11	30.1	COG0477	MFS family permease	338
2918242730	413	96.41	1	371	12	387	2.4e-59	195.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918242731	1059	99.9	2	1040	1	1013	0.0e+00	1173.8	COG0841	Multidrug efflux pump subunit AcrB	1009
2918242732	471	98.26	13	470	1	452	2.0e-115	380.4	COG1538	Outer membrane protein TolC	457
2918242735	352	65.49	7	345	106	346	2.2e-15	51.5	COG0457	Tetratricopeptide (TPR) repeat	291
2918242736	536	79.44	29	401	80	392	1.7e-50	166.6	COG0642	Signal transduction histidine kinase	336
2918242737	689	71.57	139	553	110	391	2.9e-48	159.3	COG0642	Signal transduction histidine kinase	336
2918242737	689	91.73	564	689	7	128	2.2e-15	49.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918242738	229	94.9	1	229	7	192	9.2e-39	127.6	COG0693	Putative intracellular protease/amidase	188
2918242740	358	95.59	1	358	14	360	0.0e+00	444.6	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
2918242741	525	96.11	258	514	5	251	6.5e-77	251.7	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918242742	295	96.27	1	293	8	291	5.4e-77	253.2	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
2918242743	523	97.95	76	520	3	431	2.1e-100	330.6	COG1253	Hemolysin or related protein, contains CBS domains	429
2918242744	133	25.19	3	105	66	133	1.0e-02	9.9	COG1360	Flagellar motor protein MotB	244
2918242746	194	96.63	1	194	5	205	1.7e-37	122.9	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918242747	259	79.55	127	259	21	125	6.3e-26	84.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918242749	741	96.25	2	741	27	719	0.0e+00	675.9	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
2918242750	218	96	1	218	6	221	2.4e-95	312.5	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
2918242751	232	98.18	4	223	2	217	5.2e-93	304.6	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
2918242752	296	97.67	1	296	1	294	2.0e-68	225.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242753	273	92.91	1	273	10	271	1.2e-82	271.3	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2918242754	1026	92.74	3	1026	3	1075	0.0e+00	1004.4	COG0587	DNA polymerase III, alpha subunit	1139
2918242755	472	98.13	12	459	5	371	6.8e-18	56.6	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918242756	206	72.8	3	206	18	207	2.4e-16	53.7	COG4544	Uncharacterized conserved protein	260
2918242757	202	98.52	1	202	2	201	1.4e-56	185.5	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2918242758	219	94.12	1	217	1	208	1.8e-49	162.8	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2918242759	250	92.61	1	246	7	244	2.1e-32	107.3	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2918242760	173	87.63	1	166	17	179	2.7e-40	132.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918242761	348	64.27	23	341	33	354	9.1e-35	114.5	COG0753	Catalase	496
2918242762	177	96.69	1	173	5	179	2.4e-40	132.3	COG3038	Cytochrome b561	181
2918242763	401	47.26	225	401	11	191	1.6e-26	20.5	COG0477	MFS family permease	338
2918242763	401	69.45	12	289	8	273	1.6e-26	70.6	COG0477	MFS family permease	338
2918242764	172	46.15	1	129	10	69	7.5e-15	50.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918242767	196	96.06	1	196	6	200	3.1e-68	223.7	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
2918242768	243	92.16	2	237	4	250	1.1e-35	117.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918242770	249	78.03	120	246	20	122	1.1e-23	77.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918242771	502	96.61	8	500	8	377	1.8e-27	87.4	COG0477	MFS family permease	338
2918242772	378	95.74	7	378	8	344	3.0e-106	349.1	COG1566	Multidrug resistance efflux pump	352
2918242773	290	93.56	5	290	18	293	3.1e-23	77.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918242774	206	97.6	3	203	3	205	1.2e-42	139.7	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918242775	529	99.53	28	500	2	429	0.0e+00	484.1	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
2918242776	406	98.02	1	404	1	396	0.0e+00	546.6	COG4277	Predicted DNA-binding protein with the Helix-hairpin-helix motif	404
2918242778	729	96.94	2	729	23	720	0.0e+00	724.8	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
2918242779	154	82.01	1	153	7	161	1.7e-08	25.9	COG3945	Hemerythrin-like domain	189
2918242780	880	12.33	13	138	4	119	0.0e+00	148.8	COG0178	Excinuclease UvrABC ATPase subunit	935
2918242780	880	71.73	136	880	265	939	0.0e+00	850.5	COG0178	Excinuclease UvrABC ATPase subunit	935
2918242782	198	43.54	1	198	14	195	2.9e-31	103.2	COG2995	Uncharacterized paraquat-inducible protein A	418
2918242783	214	46.89	2	210	219	414	1.7e-73	242.1	COG2995	Uncharacterized paraquat-inducible protein A	418
2918242784	550	96.93	3	544	4	539	0.0e+00	460	COG3008	Paraquat-inducible protein B	553
2918242785	185	94.74	1	172	5	184	3.1e-20	63.7	COG3009	Uncharacterized lipoprotein YmbA	190
2918242789	185	69.19	2	175	1	128	1.7e-20	68.2	COG0563	Adenylate kinase or related kinase	178
2918242790	135	96.32	1	132	4	134	2.0e-39	129.1	COG0864	Metal-responsive transcriptional regulator, contains CopG/Arc/MetJ DNA-binding domain	136
2918242791	524	94.64	10	519	17	563	3.0e-96	317.9	COG0747	ABC-type transport system, periplasmic component	556
2918242792	313	99.69	1	310	1	317	5.2e-110	362.3	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918242793	281	90.94	4	281	26	296	6.4e-95	311.9	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918242794	256	75.38	5	254	17	261	2.4e-66	218.3	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918242795	270	97.25	1	259	2	249	1.4e-75	248.3	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
2918242797	152	70.59	1	148	7	114	1.9e-32	107	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2918242798	508	97.01	16	504	12	497	0.0e+00	635.6	COG0753	Catalase	496
2918242799	338	78.03	211	337	23	125	9.1e-21	67.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918242800	394	99.49	3	394	3	394	0.0e+00	441.6	COG0183	Acetyl-CoA acetyltransferase	392
2918242801	282	85.71	1	282	2	283	6.8e-110	361.8	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918242802	196	77.99	13	195	20	182	7.3e-23	76.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918242803	298	96.66	2	293	4	292	2.5e-74	244.1	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918242804	180	96.94	7	180	3	192	2.5e-44	145.9	COG0693	Putative intracellular protease/amidase	188
2918242805	285	98.88	38	283	2	266	5.5e-67	220.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918242808	455	85.32	46	320	47	325	1.3e-68	225.6	COG3344	Retron-type reverse transcriptase	328
2918242814	40	3.86	1	38	251	284	2.2e-03	9.7	COG3002	Uncharacterized conserved protein YbcC, UPF0753/DUF2309 family	880
2918242815	137	55.65	1	137	100	232	7.1e-33	108.6	COG1186	Protein chain release factor B	239
2918242816	353	87.12	12	336	36	319	5.6e-91	299	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918242817	461	91.56	5	440	24	435	1.2e-50	164.8	COG2271	Sugar phosphate permease	448
2918242818	217	90.09	1	216	18	226	2.9e-56	184.8	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918242819	217	96.23	3	212	7	210	3.5e-65	213.9	COG0684	Regulator of RNase E activity RraA	210
2918242820	181	83.5	1	175	4	175	8.8e-33	108.2	COG1335	Nicotinamidase-related amidase	205
2918242821	224	96.12	1	209	4	201	4.0e-36	119.2	COG1335	Nicotinamidase-related amidase	205
2918242822	326	98.01	19	314	3	297	9.0e-53	174.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242823	247	98.37	2	247	4	245	7.6e-82	269.1	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2918242824	225	93.37	6	225	9	191	9.7e-40	130.9	COG0693	Putative intracellular protease/amidase	188
2918242825	240	97.33	1	240	1	219	1.3e-48	155	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
2918242826	128	97.69	1	126	2	128	8.4e-31	101.6	COG4460	Uncharacterized protein	130
2918242827	234	66.52	20	189	2	150	7.6e-47	153.7	COG2323	Uncharacterized membrane protein YcaP, DUF421 family	224
2918242828	292	96.68	1	292	1	291	1.4e-65	216.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242829	353	97.6	12	349	8	333	1.3e-96	317.6	COG2855	Uncharacterized membrane protein YadS	334
2918242830	452	95.09	1	445	16	441	5.4e-91	299.8	COG1457	Purine-cytosine permease or related protein	442
2918242831	434	98.3	24	434	2	406	0.0e+00	494.3	COG0004	Ammonia channel protein AmtB	409
2918242832	441	86.71	2	421	60	483	2.0e-120	393.7	COG0069	Glutamate synthase domain 2	485
2918242833	224	62.5	2	214	62	251	2.3e-32	107.1	COG0070	Glutamate synthase domain 3	301
2918242834	301	12.63	1	67	12	58	4.4e-53	29.1	COG0067	Glutamate synthase domain 1	371
2918242834	301	57.8	65	301	156	370	4.4e-53	144.3	COG0067	Glutamate synthase domain 1	371
2918242835	444	98.88	1	443	5	445	0.0e+00	436	COG0174	Glutamine synthetase	443
2918242836	197	55.38	14	152	2	73	5.7e-12	41.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918242837	288	98.61	1	288	4	286	5.5e-123	404.6	COG0788	Formyltetrahydrofolate hydrolase	287
2918242838	303	99.3	8	292	1	282	1.3e-114	376.3	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
2918242839	413	97.94	26	402	3	382	9.6e-82	269.6	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918242840	101	82.83	1	93	1	82	2.4e-18	60.7	COG4311	Sarcosine oxidase delta subunit	97
2918242841	967	98.84	23	468	2	426	2.7e-38	126.4	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918242841	967	99.22	583	966	2	383	3.1e-103	339.6	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
2918242842	200	62.43	20	188	46	163	1.3e-09	32.2	COG4583	Sarcosine oxidase gamma subunit	189
2918242843	291	97.34	3	291	3	295	1.1e-73	242.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242844	339	88.68	4	339	34	315	2.5e-78	258.3	COG0657	Acetyl esterase/lipase	312
2918242845	240	88.57	1	238	2	249	2.8e-62	205.1	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2918242846	97	97.92	1	95	2	95	1.5e-37	122.3	COG5470	Uncharacterized conserved protein, DUF1330 family	96
2918242847	373	88.78	204	373	2	175	7.9e-28	90.9	COG0807	GTP cyclohydrolase II	193
2918242847	373	98.52	1	204	3	202	6.2e-82	267.8	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
2918242848	341	92.86	1	340	14	364	5.8e-66	217.4	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918242849	305	88.89	22	304	25	280	1.1e-83	275.2	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918242850	269	93.26	7	269	14	262	2.5e-81	267.2	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918242851	382	98.3	10	369	3	349	3.5e-124	409	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918242852	303	99	5	300	1	298	3.1e-66	218.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242853	363	98.28	2	363	4	345	2.1e-128	422.6	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2918242854	648	50.43	528	647	2	118	1.7e-52	68.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918242854	648	57.33	5	169	2	134	1.7e-52	105.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918242854	648	73.35	184	514	101	389	2.7e-50	166.8	COG0642	Signal transduction histidine kinase	336
2918242855	291	69.8	4	288	118	392	4.4e-62	205.3	COG0642	Signal transduction histidine kinase	336
2918242856	338	84.93	3	139	12	135	2.4e-15	50.3	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2918242857	134	91.78	1	134	9	142	1.3e-26	87.3	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2918242858	120	81.2	1	113	5	99	7.0e-22	71.9	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918242859	283	96.58	157	273	2	114	1.0e-26	87	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918242860	279	96.74	44	267	3	210	7.1e-52	170.6	COG0625	Glutathione S-transferase	211
2918242861	656	98.7	4	559	7	538	0.0e+00	687.5	COG1292	Choline-glycine betaine transporter	537
2918242862	567	99.79	1	562	1	480	0.0e+00	483.7	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918242863	233	95.45	5	226	7	216	2.6e-39	129.2	COG2964	Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains	220
2918242864	307	85.26	2	304	25	319	4.2e-66	217.8	COG1171	Threonine dehydratase	347
2918242865	90	44.14	1	90	82	145	2.2e-05	19.2	COG3212	Uncharacterized membrane protein YkoI	144
2918242866	365	93.67	1	343	25	394	7.0e-84	276.2	COG0019	Diaminopimelate decarboxylase	394
2918242867	414	98.2	2	412	1	381	0.0e+00	465.4	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
2918242868	165	89.82	2	165	9	158	3.2e-27	89.4	COG0597	Lipoprotein signal peptidase	167
2918242869	726	66.75	185	590	127	389	1.7e-55	183.1	COG0642	Signal transduction histidine kinase	336
2918242870	457	95.12	133	349	4	198	4.4e-49	160.9	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2918242871	216	16.41	170	216	219	261	8.2e-37	15.4	COG3103	Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family	205
2918242871	216	58.78	16	181	14	167	8.2e-37	106.3	COG3103	Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family	205
2918242873	810	97.48	77	810	21	795	3.8e-58	192.2	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918242874	324	97.52	1	324	7	321	1.7e-93	307.6	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918242875	170	88.17	1	170	11	174	3.3e-31	102.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918242876	375	85.56	60	302	25	267	5.9e-18	59.2	COG2801	Transposase InsO and inactivated derivatives	232
2918242877	293	93.36	4	293	2	282	5.7e-53	175.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242878	308	94.84	2	308	4	334	2.7e-76	248.4	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
2918242879	228	51.85	32	191	34	117	1.2e-03	13.9	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918242880	541	95.53	68	541	20	425	2.4e-100	331.1	COG0840	Methyl-accepting chemotaxis protein	408
2918242881	467	97.1	1	462	10	444	1.7e-85	281.6	COG1457	Purine-cytosine permease or related protein	442
2918242882	161	81.62	1	159	12	162	6.4e-40	131.2	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918242883	347	95.34	7	345	9	335	4.6e-61	201	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918242886	277	95.25	4	265	13	293	6.0e-45	148.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918242887	493	99.37	6	484	2	477	0.0e+00	589.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918242888	161	82.16	3	157	13	164	9.4e-39	127.3	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918242889	129	95.97	7	127	4	122	2.2e-31	103.1	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918242890	250	93.97	8	232	12	229	7.2e-54	177	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918242891	187	81.51	35	166	5	123	3.6e-23	76.3	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2918242892	296	93.69	1	295	1	282	2.0e-54	179.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242893	378	93.23	5	376	22	393	2.2e-60	199	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918242894	314	79.75	5	314	67	326	3.0e-71	234.3	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918242895	264	95.54	18	242	2	215	4.2e-49	161.5	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2918242896	542	95.5	4	538	11	562	3.1e-73	241.8	COG0747	ABC-type transport system, periplasmic component	556
2918242897	316	99.37	1	312	1	316	7.3e-91	299.2	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918242898	299	88.26	8	297	24	286	7.2e-83	272.2	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918242899	540	98.55	1	537	5	548	0.0e+00	640.4	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918242900	444	97.38	11	414	9	342	1.1e-94	311.7	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918242901	366	96.5	8	357	9	339	4.1e-77	253.9	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918242902	520	98.46	40	514	5	451	3.3e-75	248.1	COG1231	Monoamine oxidase	450
2918242903	164	88.97	12	164	15	135	1.1e-23	78.1	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918242904	807	96.86	4	807	26	795	7.7e-59	194.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918242905	332	96.6	1	330	4	316	8.6e-102	335	COG0385	Predicted Na+-dependent transporter	319
2918242906	379	93.07	1	379	18	393	1.8e-58	193.1	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918242911	106	97.22	1	106	1	105	7.0e-34	110.8	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
2918242912	294	96.01	1	289	8	296	7.9e-41	134.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918242913	253	91.07	3	220	4	207	3.9e-52	171.4	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2918242914	347	99.21	1	345	3	377	1.3e-62	206.4	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918242915	650	99.17	3	367	3	362	3.8e-101	333.1	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918242916	198	57.69	18	146	2	76	6.7e-17	56.8	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918242917	435	84.31	5	304	46	319	5.5e-46	151.4	COG0226	ABC-type phosphate transport system, periplasmic component	318
2918242918	363	96.48	63	331	2	248	1.3e-74	245.3	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918242919	159	67.28	1	140	46	154	5.0e-09	31.5	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918242920	409	98.5	1	401	1	393	1.3e-97	321.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918242921	308	98.34	6	300	2	297	7.6e-48	158.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242922	384	97.15	4	382	2	376	0.0e+00	440.6	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
2918242923	394	96.96	5	394	9	391	1.0e-95	315	COG2814	Predicted arabinose efflux permease, MFS family	394
2918242924	304	98.01	1	300	3	297	4.7e-71	234.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242925	276	75	148	273	27	125	8.0e-25	81	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918242926	194	98.08	1	194	2	205	1.1e-36	120.5	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918242927	396	96.96	2	390	10	392	1.1e-115	380.7	COG2814	Predicted arabinose efflux permease, MFS family	394
2918242929	350	98.53	1	347	5	340	4.3e-124	408.3	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2918242930	301	83.33	176	298	12	121	1.4e-26	86.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918242931	168	84.41	2	166	18	174	6.3e-34	111.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918242932	325	95.67	1	322	12	320	3.3e-83	273.8	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918242933	811	95.83	65	809	30	719	0.0e+00	572.5	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
2918242934	181	97.25	13	181	2	178	2.4e-31	103.4	COG1514	2'-5' RNA ligase	180
2918242935	299	98.28	4	294	4	289	3.2e-111	365.5	COG3555	Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily	291
2918242936	189	37.57	1	165	113	183	3.0e-10	33.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918242939	708	96.6	1	708	28	795	5.4e-88	291.1	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918242940	388	96.01	1	351	13	325	1.0e-93	308.3	COG3503	Uncharacterized membrane protein	323
2918242942	337	87.96	1	335	33	317	1.6e-42	140.4	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2918242943	338	97.01	2	337	9	333	1.5e-92	304.5	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918242944	262	94.96	10	260	3	247	5.2e-82	269.4	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
2918242945	146	81.25	4	115	25	128	6.6e-26	85.5	COG3794	Plastocyanin	128
2918242951	165	71.6	7	153	41	156	7.7e-15	49.8	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918242953	531	94.54	347	523	10	182	4.5e-54	174.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918242954	337	70.61	1	335	40	284	1.3e-46	152.2	COG4294	UV DNA damage repair endonuclease	347
2918242957	257	93.94	1	256	5	252	9.9e-49	160.9	COG1192	Cellulose biosynthesis protein BcsQ	259
2918242959	716	96.23	1	716	23	787	1.1e-73	243.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918242961	245	98.35	2	242	3	240	8.0e-107	350.3	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918242962	215	92.98	1	215	15	226	8.6e-72	235.9	COG0765	ABC-type amino acid transport system, permease component	222
2918242963	221	92.11	2	220	16	225	2.7e-62	204.8	COG0765	ABC-type amino acid transport system, permease component	222
2918242964	261	97.17	1	261	1	275	1.6e-51	169.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918242965	230	92.53	2	228	9	231	7.1e-54	177	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918242966	441	51.96	231	433	8	206	7.6e-42	42.3	COG0477	MFS family permease	338
2918242966	441	63.97	11	263	2	246	7.6e-42	100.2	COG0477	MFS family permease	338
2918242967	1044	99.42	1	1044	1	1024	0.0e+00	1402.2	COG3696	Cu/Ag efflux pump CusA	1027
2918242968	396	94.62	1	395	14	382	1.2e-42	140.8	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918242969	413	89.35	6	413	41	451	8.6e-60	197.3	COG1538	Outer membrane protein TolC	457
2918242970	149	97.95	3	148	2	144	3.9e-66	215.6	COG0757	3-dehydroquinate dehydratase	146
2918242971	282	97.54	1	282	2	278	7.9e-81	265.7	COG0169	Shikimate 5-dehydrogenase	283
2918242972	437	73.81	8	434	69	426	1.2e-53	176.8	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918242973	325	96.92	3	325	5	319	1.2e-112	370.4	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918242974	451	48.83	255	449	4	190	4.5e-42	37.3	COG0477	MFS family permease	338
2918242974	451	74.93	29	294	5	291	4.5e-42	109.2	COG0477	MFS family permease	338
2918242975	403	96.67	17	397	7	383	5.9e-50	164.7	COG0006	Xaa-Pro aminopeptidase	384
2918242976	752	97.97	1	749	15	737	0.0e+00	1291.6	COG0376	Catalase (peroxidase I)	730
2918242977	302	98.34	9	302	2	297	2.5e-41	136.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918242978	292	97.01	9	292	5	296	2.8e-40	132.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918242979	274	93.26	1	273	7	269	6.5e-84	275.6	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2918242980	249	98.72	1	249	1	232	1.1e-45	150.5	COG2243	Precorrin-2 methylase	234
2918242982	173	97.95	24	169	3	145	1.6e-24	82.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918242984	272	91.9	6	272	19	279	3.9e-72	237.1	COG0169	Shikimate 5-dehydrogenase	283
2918242986	306	73.79	1	306	10	299	3.6e-77	254.7	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2918242987	144	15.03	4	132	398	495	1.0e-04	15.1	COG2433	Possible nuclease of RNase H fold, RuvC/YqgF family	652
2918242988	442	96.1	5	442	5	423	1.6e-129	426.8	COG3486	Lysine/ornithine N-monooxygenase	436
2918242989	399	89.16	6	391	6	400	2.3e-75	247.8	COG3182	Uncharacterized iron-regulated membrane protein	442
2918242993	305	97.38	2	302	8	304	6.5e-76	249.7	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
2918242994	248	91.73	11	247	4	236	6.2e-70	229.9	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
2918242995	299	96.74	15	295	5	271	8.5e-73	239.4	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2918242996	303	90.82	5	302	3	279	1.0e-22	74.7	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
2918242998	239	95.08	1	239	7	238	2.6e-80	263.4	COG3208	Surfactin synthase thioesterase subunit	244
2918242999	73	97.18	1	70	2	70	1.2e-34	112.5	COG3251	Uncharacterized conserved protein YbdZ, MbtH family	71
2918243000	205	97.6	2	205	3	205	2.8e-51	168.1	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918243001	133	38.07	20	122	112	194	7.8e-04	13.3	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918243002	125	88.72	2	125	7	124	3.9e-20	66.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918243003	408	70.05	11	400	114	389	1.4e-58	193.8	COG0642	Signal transduction histidine kinase	336
2918243004	191	52.27	1	189	159	342	3.4e-51	168.7	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918243005	273	98.15	8	273	3	267	5.9e-61	200.5	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918243006	1153	85.71	879	1007	6	119	1.1e-73	50.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918243006	1153	90.98	294	881	6	126	1.1e-73	61.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918243006	1153	94.2	6	206	5	199	9.0e-22	72.1	COG5278	Extracellular (periplasmic) sensor domain CHASE3 (specificity unknown)	207
2918243006	1153	95.49	1025	1152	4	130	1.1e-73	135.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918243007	119	87.97	1	118	7	123	1.1e-16	55.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918243009	700	65.16	167	700	214	645	6.1e-130	428.7	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918243010	62	28.68	3	59	17	55	6.7e-04	14.1	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918243012	335	96.31	21	335	5	317	7.2e-82	269.3	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918243013	223	79.9	12	221	6	172	1.4e-21	72.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918243014	635	94.77	272	633	16	359	3.0e-123	405.6	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
2918243014	635	96.4	1	269	3	270	5.3e-54	175.1	COG1082	Sugar phosphate isomerase/epimerase	274
2918243015	458	50.91	234	441	10	204	1.4e-38	34.8	COG0477	MFS family permease	338
2918243015	458	70.76	9	276	3	273	1.4e-38	97.5	COG0477	MFS family permease	338
2918243016	470	96.11	14	470	3	447	1.0e-98	325.3	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
2918243017	322	98.01	16	312	2	296	4.1e-48	159	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918243018	237	93.42	2	236	11	237	8.0e-64	209.8	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
2918243019	463	98.45	23	419	2	383	1.5e-65	216.3	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918243020	438	94.22	2	425	22	445	1.8e-109	360.8	COG2271	Sugar phosphate permease	448
2918243021	289	96.35	6	289	5	294	4.1e-59	195.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918243023	258	99.22	1	258	1	255	2.2e-98	323.5	COG4106	Trans-aconitate methyltransferase	257
2918243024	470	96.97	10	470	8	455	0.0e+00	457.1	COG1113	L-asparagine transporter and related permeases	462
2918243025	475	97.59	8	472	2	446	6.5e-107	352.5	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918243029	250	98.71	10	247	2	230	6.2e-71	232.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918243030	458	87.31	5	458	45	388	8.7e-53	173.9	COG0642	Signal transduction histidine kinase	336
2918243031	649	97.86	2	649	16	700	0.0e+00	648.2	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
2918243032	304	98.34	10	304	1	296	1.5e-59	196.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918243033	222	99.08	3	220	1	216	6.5e-66	216.8	COG0819	Thiaminase	218
2918243034	215	98.62	3	214	3	217	4.2e-34	112.8	COG0819	Thiaminase	218
2918243036	191	13.42	6	82	9	50	1.5e-06	9.8	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2918243036	191	16.93	89	178	256	308	1.5e-06	11.3	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2918243038	413	89.39	4	410	27	405	1.3e-77	255.4	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918243039	133	43.62	4	116	47	111	4.5e-04	14.7	COG5642	Uncharacterized conserved protein, DUF2384 family	149
2918243042	135	94.16	2	131	4	132	1.3e-32	107.3	COG4319	Ketosteroid isomerase homolog	137
2918243044	223	88.26	4	221	13	215	5.5e-20	66.3	COG1266	Membrane protease YdiL, CAAX protease family	226
2918243046	52	29.93	1	49	90	130	8.4e-08	27	COG4319	Ketosteroid isomerase homolog	137
2918243049	274	81.06	140	273	19	125	4.9e-21	69.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918243050	128	75.97	6	125	28	125	1.3e-17	58.1	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2918243055	56	8.84	1	51	6	21	1.4e-03	12.9	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
2918243061	267	100	1	263	1	272	5.7e-67	220.8	COG3183	Predicted restriction endonuclease, HNH family	272
2918243062	424	60.58	267	402	24	106	1.2e-06	22.7	COG2445	Uncharacterized conserved protein YutE, UPF0331/DUF86 family	138
2918243063	128	18.07	4	118	16	103	5.0e-09	30	COG1061	Superfamily II DNA or RNA helicase	442
2918243064	859	58.32	6	349	123	406	5.3e-23	69.1	COG1061	Superfamily II DNA or RNA helicase	442
2918243068	506	98.77	96	252	3	163	2.8e-37	121.9	COG3436	Transposase	157
2918243069	111	57.67	4	104	40	133	1.1e-13	45.5	COG3436	Transposase	157
2918243070	106	61.54	1	95	4	75	1.4e-15	52.2	COG2963	Transposase and inactivated derivatives	116
2918243072	243	94.97	6	226	10	198	5.2e-27	89.6	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918243073	547	12.76	363	547	728	876	1.3e-07	5.1	COG1196	Chromosome segregation ATPase	1163
2918243073	547	16.18	147	374	326	514	1.3e-07	23.6	COG1196	Chromosome segregation ATPase	1163
2918243076	598	78.91	8	561	51	585	1.8e-47	155.7	COG4928	Predicted P-loop ATPase, KAP-like	646
2918243077	168	84.41	1	158	28	184	2.6e-53	174.6	COG3575	Uncharacterized protein	184
2918243078	511	98.16	97	257	4	163	2.9e-39	128.6	COG3436	Transposase	157
2918243079	111	57.67	4	104	40	133	4.5e-15	50	COG3436	Transposase	157
2918243080	76	58.97	1	75	4	72	4.0e-16	54	COG2963	Transposase and inactivated derivatives	116
2918243083	353	77.99	13	149	21	144	1.3e-52	44.8	COG4804	Predicted nuclease of restriction endonuclease-like (RecB) superfamily,  DUF1016 family	159
2918243083	353	94.34	119	269	9	158	1.3e-52	133.3	COG4804	Predicted nuclease of restriction endonuclease-like (RecB) superfamily,  DUF1016 family	159
2918243085	122	88	2	121	1	110	3.8e-04	12.5	COG3293	Transposase	124
2918243087	118	75.76	19	118	1	100	8.9e-22	72.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918243088	100	96.81	3	96	2	92	1.1e-36	119.5	COG0776	Bacterial nucleoid DNA-binding protein	94
2918243089	793	100	142	792	1	652	0.0e+00	690.8	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
2918243090	338	99.11	1	336	4	337	2.9e-129	425.8	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
2918243091	118	99.15	1	118	1	117	8.3e-57	185	COG0292	Ribosomal protein L20	118
2918243092	64	96.92	1	64	1	63	2.4e-27	89.7	COG0291	Ribosomal protein L35	65
2918243093	183	96.59	8	183	7	176	4.6e-76	248.7	COG0290	Translation initiation factor IF-3	176
2918243094	640	98.82	34	639	2	588	0.0e+00	884.4	COG0441	Threonyl-tRNA synthetase	589
2918243096	70	97.01	4	70	2	66	1.0e-33	109.7	COG1278	Cold shock protein, CspA family	67
2918243099	335	99.04	23	335	3	312	3.7e-105	346.1	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
2918243100	134	99.26	1	134	2	135	1.3e-42	139.6	COG1869	D-ribose pyranose/furanose isomerase RbsD	135
2918243101	302	98.1	4	302	1	310	3.6e-84	277	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918243102	342	99.7	2	335	1	333	6.4e-122	401.4	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918243103	327	96.87	15	326	9	317	4.3e-89	292.8	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918243104	517	99.2	2	500	4	500	0.0e+00	587.3	COG1129	ABC-type sugar transport system, ATPase component	500
2918243105	317	93.27	1	317	9	313	1.1e-79	262.1	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918243106	363	94.41	4	363	17	354	3.2e-108	356.2	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
2918243108	323	91.56	2	238	11	227	2.1e-83	273.7	COG2356	Endonuclease I	237
2918243113	427	98.71	26	407	4	386	1.6e-81	269	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918243115	250	96.48	1	250	6	252	1.5e-82	271.2	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918243116	80	32.41	19	78	14	48	1.7e-04	16.1	COG2811	Archaeal/vacuolar-type H+-ATPase subunit H	108
2918243117	297	95.68	2	296	2	289	1.0e-43	144.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918243118	403	98.28	1	403	6	405	0.0e+00	687.8	COG3633	Na+/serine symporter	407
2918243119	215	96.74	4	215	5	212	3.8e-72	237.1	COG3132	Uncharacterized conserved protein YceH, UPF0502 family	215
2918243121	520	99.23	1	520	1	517	0.0e+00	927.4	COG3634	Alkyl hydroperoxide reductase subunit AhpF	520
2918243122	187	95.83	1	187	2	185	3.0e-74	243.1	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
2918243123	451	99.34	1	447	3	454	0.0e+00	490.9	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918243124	279	92.76	1	279	3	271	1.3e-116	383.2	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
2918243125	302	98.01	11	302	4	298	7.6e-102	334.9	COG3258	Cytochrome c	293
2918243126	216	52.59	117	213	42	112	2.8e-47	62.3	COG2863	Cytochrome c553	121
2918243126	216	86.67	4	123	7	123	2.8e-47	90.7	COG2863	Cytochrome c553	121
2918243130	357	96.23	3	357	5	336	5.8e-83	273.5	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2918243131	252	91.76	3	252	20	264	2.1e-53	175.7	COG0725	ABC-type molybdate transport system, periplasmic component	258
2918243132	226	96.44	3	225	3	219	6.8e-78	255.5	COG4149	ABC-type molybdate transport system, permease component	225
2918243133	363	96.88	4	363	10	350	0.0e+00	434.6	COG4148	ABC-type molybdate transport system, ATPase component	352
2918243134	338	92.13	6	337	17	344	3.7e-114	375.9	COG3569	DNA topoisomerase IB	354
2918243135	65	84.93	1	65	1	62	2.2e-30	99.2	COG1551	sRNA-binding carbon storage regulator CsrA	73
2918243136	117	50.43	2	117	2	118	1.1e-25	84.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918243137	481	85.44	239	465	3	225	8.9e-42	56.8	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
2918243137	481	91.95	4	233	2	241	8.9e-42	76.5	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
2918243138	380	67.77	18	379	122	388	1.7e-51	170.2	COG0642	Signal transduction histidine kinase	336
2918243140	137	88.19	4	137	12	138	9.3e-38	124.2	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918243148	339	86.25	33	334	9	284	4.7e-76	250.4	COG0616	Periplasmic serine protease, ClpP class	317
2918243149	236	91.87	2	233	4	195	1.3e-29	96.2	COG0406	Broad specificity phosphatase PhoE	208
2918243150	105	70.9	1	104	23	117	5.5e-20	66.6	COG3255	Putative sterol carrier protein	134
2918243151	355	97.86	9	346	2	321	1.3e-94	311.5	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2918243152	255	99.25	7	254	2	267	9.0e-70	229.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918243154	101	44.27	22	101	73	130	1.6e-17	58.3	COG5455	Periplasmic regulator RcnB of Ni and Co efflux	129
2918243155	386	94.54	200	380	9	181	5.9e-49	160.5	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918243156	60	14.68	1	59	103	150	1.7e-03	12.1	COG4531	ABC-type Zn2+ transport system, periplasmic component/surface adhesin	318
2918243158	609	98.96	15	609	3	480	1.6e-124	410.5	COG0471	Di- and tricarboxylate transporter	461
2918243159	469	94.54	278	462	9	181	2.4e-53	174.8	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918243160	253	97.3	1	253	4	255	4.5e-41	135.4	COG0730	Uncharacterized membrane protein YfcA	258
2918243161	299	97.34	4	299	2	294	1.1e-61	203.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918243163	163	79.37	1	145	13	162	3.6e-12	40.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918243169	223	98.28	1	223	4	231	1.4e-54	179.5	COG0670	Integral membrane protein, interacts with FtsH	233
2918243170	459	94.74	11	459	12	443	0.0e+00	457	COG2233	Xanthine/uracil permease	451
2918243171	130	100	1	127	1	126	4.5e-36	118.2	COG1553	Sulfur relay (sulfurtransferase) complex TusBCD TusD component, DsrE family	126
2918243172	119	98.31	2	119	2	117	1.1e-35	116.7	COG2923	Sulfur relay (sulfurtransferase) complex TusC component, DsrF/TusC family	118
2918243173	98	100	3	97	1	96	6.3e-20	65.5	COG2168	Sulfur transfer complex TusBCD TusB component, DsrH family	96
2918243174	111	99.1	1	111	2	111	1.8e-42	138.6	COG2920	Sulfur relay (sulfurtransferase) protein, DsrC/TusE family	111
2918243175	338	95.29	19	338	2	325	1.4e-64	212.7	COG0547	Anthranilate phosphoribosyltransferase	338
2918243176	320	100	1	311	1	322	0.0e+00	480.4	COG0435	Glutathionyl-hydroquinone reductase	324
2918243177	462	98.58	1	210	1	208	3.5e-63	207.2	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
2918243177	462	99.18	213	458	3	244	5.0e-107	351.2	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2918243178	426	99.07	1	426	1	427	0.0e+00	619.4	COG0172	Seryl-tRNA synthetase	429
2918243179	124	94.44	1	124	4	122	7.1e-35	114.3	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
2918243180	441	97.48	1	436	10	435	0.0e+00	613	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
2918243181	207	97.18	1	207	5	211	1.1e-46	153.6	COG2834	Outer membrane lipoprotein-sorting protein	211
2918243182	803	20.06	15	225	15	201	0.0e+00	55.8	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2918243182	803	57.73	222	801	389	926	0.0e+00	805.3	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2918243183	226	95.02	10	226	2	211	2.3e-92	302.2	COG2360	Leu/Phe-tRNA-protein transferase	221
2918243184	235	93.28	1	235	7	242	5.0e-94	309	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
2918243185	72	96	1	72	1	72	1.3e-37	121.7	COG0361	Translation initiation factor IF-1	75
2918243186	756	41.61	416	752	469	803	0.0e+00	457.7	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918243186	756	50.43	1	429	2	407	0.0e+00	512.3	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918243187	120	89.72	13	119	11	106	3.3e-41	134	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
2918243188	86	98.51	1	67	1	66	5.2e-31	100.9	COG1278	Cold shock protein, CspA family	67
2918243189	418	99.51	9	418	2	407	0.0e+00	630	COG0538	Isocitrate dehydrogenase	407
2918243191	741	99.06	1	741	5	741	0.0e+00	1319	COG2838	Monomeric isocitrate dehydrogenase	744
2918243192	146	82.19	1	137	8	127	5.1e-13	43.8	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2918243193	374	99.16	9	368	3	356	0.0e+00	494.9	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
2918243194	206	97.1	1	206	1	201	2.4e-77	253.8	COG2915	Regulator of phage lambda lysogenization HflD, binds to CII and stimulates its degradation	207
2918243195	456	99.32	12	456	1	436	0.0e+00	451.4	COG0015	Adenylosuccinate lyase	438
2918243196	388	98.7	1	387	4	383	0.0e+00	457.4	COG2850	Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain	383
2918243197	144	85.16	11	142	21	152	1.1e-26	87.7	COG2153	Predicted N-acyltransferase, GNAT family	155
2918243198	654	97.39	1	613	1	560	0.0e+00	505.5	COG0550	DNA topoisomerase IA	570
2918243199	255	98.07	3	254	4	257	3.9e-55	181.3	COG0730	Uncharacterized membrane protein YfcA	258
2918243200	276	89.08	3	268	20	272	4.8e-80	263.5	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
2918243201	270	99.25	1	268	3	265	5.8e-75	246.5	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918243202	500	95.74	1	500	7	500	0.0e+00	807.8	COG3067	Na+/H+ antiporter NhaB	516
2918243203	213	99.04	1	210	1	206	9.6e-54	176.1	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918243206	427	98.33	17	418	4	414	1.4e-62	206.4	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918243207	496	96.41	2	494	6	489	0.0e+00	537.8	COG1953	Cytosine/uracil/thiamine/allantoin permease	497
2918243208	479	99.3	1	448	1	428	0.0e+00	433.2	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2918243209	455	98.47	17	455	5	455	7.2e-111	365.4	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2918243210	424	94.52	336	408	4	72	1.5e-13	44.4	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2918243210	424	99.03	3	323	2	308	8.4e-80	262.5	COG0167	Dihydroorotate dehydrogenase	310
2918243211	206	92.82	2	206	13	206	8.6e-27	89.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918243212	398	52.74	198	397	8	209	1.3e-17	20.8	COG0477	MFS family permease	338
2918243212	398	71.8	4	242	5	279	1.3e-17	38.3	COG0477	MFS family permease	338
2918243213	450	98.22	1	447	1	442	0.0e+00	629.3	COG2271	Sugar phosphate permease	448
2918243214	270	48.54	28	200	41	156	4.5e-24	79.2	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918243217	598	97.12	1	591	14	619	2.5e-129	426.7	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
2918243218	500	98.56	5	499	6	484	0.0e+00	571.9	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
2918243219	327	99.67	1	327	1	299	0.0e+00	441.8	COG1023	6-phosphogluconate dehydrogenase (decarboxylating)	300
2918243220	51	12.96	3	51	55	86	1.1e-03	13.1	COG3879	Uncharacterized conserved protein YlxW, UPF0749 family	247
2918243221	172	83.87	11	168	19	174	5.5e-34	111.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918243222	309	98.14	1	308	5	321	9.4e-62	203.1	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918243223	786	96.6	93	786	28	795	1.6e-102	338.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918243224	279	91.32	25	278	15	256	2.3e-49	162.4	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
2918243225	519	98.36	43	516	2	482	0.0e+00	479.1	COG0297	Glycogen synthase	487
2918243226	589	91.94	1	582	24	605	0.0e+00	468.2	COG0296	1,4-alpha-glucan branching enzyme	628
2918243227	689	97.92	138	685	11	528	0.0e+00	497.7	COG1640	4-alpha-glucanotransferase	520
2918243228	924	99.44	1	923	5	888	0.0e+00	1048.5	COG3280	Maltooligosyltrehalose synthase	889
2918243230	717	98.58	7	717	4	697	0.0e+00	890.9	COG1523	Pullulanase/glycogen debranching enzyme	697
2918243232	736	99.68	104	735	2	632	0.0e+00	871.9	COG0296	1,4-alpha-glucan branching enzyme	628
2918243233	1103	92.59	624	1100	26	450	4.3e-124	408.6	COG3281	Predicted trehalose synthase	438
2918243233	1103	99.81	20	530	1	516	4.4e-125	413.2	COG0366	Glycosidase	505
2918243234	672	72.34	218	630	2	375	8.8e-31	97	COG0366	Glycosidase	505
2918243236	560	96.65	8	558	9	557	1.2e-125	414.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918243237	387	98.25	6	387	3	394	5.4e-129	425.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918243238	535	99.62	12	535	2	525	0.0e+00	682.5	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2918243239	270	97.74	1	261	7	265	5.5e-68	223.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918243240	649	99.54	5	649	3	645	0.0e+00	875	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918243241	217	96.06	5	216	4	198	4.3e-24	77.5	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2918243245	382	98.41	12	382	3	373	2.4e-82	271.1	COG2866	Murein tripeptide amidase MpaA	374
2918243246	324	68.39	19	161	52	170	4.2e-25	15.7	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2918243246	324	82.76	158	324	28	171	4.2e-25	72.7	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2918243247	780	92.96	26	780	60	838	0.0e+00	461	COG3188	Outer membrane usher protein FimD/PapC	835
2918243248	258	86.19	1	249	13	218	1.1e-44	146.7	COG3121	P pilus assembly protein, chaperone PapD	235
2918243249	154	87.36	1	154	23	174	7.4e-25	82.3	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2918243250	177	95.4	1	177	9	174	1.6e-24	81.2	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2918243251	177	90.8	2	177	17	174	3.8e-13	44	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2918243252	175	90.8	2	175	17	174	1.2e-09	32.3	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2918243253	745	97.87	2	744	9	742	0.0e+00	726.3	COG4251	Bacteriophytochrome (light-regulated signal transduction histidine kinase)	750
2918243254	153	87.97	3	139	8	124	2.5e-25	83.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918243255	794	50	681	793	2	117	3.1e-30	58.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918243255	794	57.33	6	157	2	134	3.1e-30	45.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918243255	794	84.26	277	661	57	388	8.7e-51	168.2	COG0642	Signal transduction histidine kinase	336
2918243257	80	84.72	11	80	6	66	1.1e-07	26.5	COG2841	Uncharacterized conserved protein YdcH, DUF465 family	72
2918243258	359	75.27	13	353	60	339	1.3e-89	295	COG1485	Predicted ATPase	367
2918243259	629	98.19	44	608	1	542	0.0e+00	664.4	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918243260	288	98.67	1	278	1	297	5.5e-47	155	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918243261	382	96.34	1	373	10	377	4.7e-108	355.6	COG3448	CBS-domain-containing membrane protein	382
2918243262	439	84.26	6	438	57	388	1.7e-35	117.3	COG0642	Signal transduction histidine kinase	336
2918243263	222	98.71	1	221	1	229	3.0e-77	253.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918243264	104	55.17	8	104	66	145	4.1e-19	63.9	COG3212	Uncharacterized membrane protein YkoI	144
2918243265	101	51.72	4	101	70	144	8.8e-22	72.6	COG3212	Uncharacterized membrane protein YkoI	144
2918243267	118	73.68	1	118	4	115	1.0e-35	116	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
2918243269	134	68.92	1	60	21	71	1.2e-14	48.3	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
2918243270	874	99.65	6	869	2	850	0.0e+00	1535.8	COG1049	Aconitase B	852
2918243272	342	69.67	49	337	66	297	4.9e-30	99.2	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918243273	330	80.78	15	326	61	329	8.3e-36	118.2	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918243274	831	31.97	2	106	89	135	3.5e-06	20.4	COG1388	LysM repeat	124
2918243276	683	93.94	1	576	19	561	0.0e+00	562	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2918243277	298	96.35	5	298	2	291	6.2e-45	148.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918243278	348	85.68	1	348	57	397	0.0e+00	447.8	COG2721	Altronate dehydratase	381
2918243279	528	98.96	6	500	3	476	2.6e-74	244.7	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918243280	494	99.56	8	492	2	455	0.0e+00	564.1	COG2079	2-methylcitrate dehydratase PrpD	453
2918243281	396	99.47	4	396	2	377	0.0e+00	593.2	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
2918243282	862	98.16	4	859	16	869	0.0e+00	1123.2	COG1048	Aconitase A	861
2918243283	375	95.45	3	375	19	396	0.0e+00	456.6	COG0372	Citrate synthase	390
2918243284	296	98.28	1	292	5	290	1.3e-121	399.6	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
2918243285	238	93.97	3	233	11	228	2.7e-60	197.9	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918243286	178	97.53	1	167	2	159	2.1e-54	177.9	COG4067	Uncharacterized conserved protein	162
2918243289	447	96.57	5	447	10	460	0.0e+00	460.1	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2918243290	244	89.18	1	244	13	251	2.2e-64	211.7	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2918243291	136	93.6	5	129	2	118	7.3e-27	88.2	COG1725	DNA-binding transcriptional regulator YhcF, GntR family	125
2918243292	286	73.53	6	256	6	230	1.0e-62	206.5	COG1131	ABC-type multidrug transport system, ATPase component	293
2918243294	324	98.01	1	299	1	295	7.2e-60	197.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918243295	165	83.65	1	158	25	157	6.6e-17	56.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918243297	358	98.01	2	352	5	348	0.0e+00	521.9	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
2918243298	93	86.87	3	93	9	94	4.0e-32	104.8	COG2388	Predicted acetyltransferase, GNAT superfamily	99
2918243300	83	45	2	78	6	41	1.1e-03	13.1	COG5645	Uncharacterized conserved protein YceK	80
2918243301	325	93.8	4	236	16	242	1.4e-47	157	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2918243303	201	94.57	15	201	9	217	2.0e-42	140	COG2755	Lysophospholipase L1 or related esterase	216
2918243304	227	97.37	1	225	5	226	2.5e-106	348.6	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
2918243305	835	99.4	4	835	5	828	0.0e+00	859.2	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
2918243306	162	99.34	6	156	1	151	2.8e-52	171	COG0782	Transcription elongation factor, GreA/GreB family	151
2918243308	145	86.81	7	145	14	138	2.2e-33	109.9	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918243309	468	88.58	23	466	5	423	2.1e-108	357	COG4623	Membrane-bound lytic murein transglycosylase MltF	473
2918243310	265	99.61	1	264	1	256	3.8e-70	230.5	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
2918243311	492	81.88	23	492	78	425	2.2e-100	331.2	COG0840	Methyl-accepting chemotaxis protein	408
2918243312	122	65.36	1	122	34	150	2.6e-14	48.3	COG3728	Phage terminase, small subunit	179
2918243313	265	96.21	1	265	6	284	1.4e-44	146.7	COG1946	Acyl-CoA thioesterase	289
2918243314	255	97.17	1	255	5	279	2.5e-26	86.3	COG5607	CHAD domain (function unknown)	283
2918243316	346	91.85	1	345	9	301	5.8e-86	282.8	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2918243317	623	96.92	12	421	1	315	7.6e-45	148.2	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918243318	90	95.74	1	90	2	91	9.3e-37	119.6	COG0776	Bacterial nucleoid DNA-binding protein	94
2918243319	798	98.47	1	775	7	778	0.0e+00	1144	COG0466	ATP-dependent Lon protease, bacterial type	782
2918243320	427	99.02	17	425	1	405	0.0e+00	695.6	COG1219	ATP-dependent protease Clp, ATPase subunit	408
2918243321	213	96	14	213	3	194	1.4e-90	296.8	COG0740	ATP-dependent protease ClpP, protease subunit	200
2918243322	437	98.88	1	434	1	443	0.0e+00	494.9	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
2918243324	60	41.38	2	60	59	106	2.0e-10	35.4	COG4679	Phage-related protein	116
2918243325	99	67.12	29	88	2	50	9.2e-04	13.3	COG3655	DNA-binding transcriptional regulator, XRE family	73
2918243330	284	98.24	4	284	2	280	1.3e-117	386.1	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
2918243331	521	70.59	147	521	125	424	2.9e-72	238.5	COG0840	Methyl-accepting chemotaxis protein	408
2918243332	436	98.09	1	424	3	412	0.0e+00	441.4	COG1301	Na+/H+-dicarboxylate symporter	415
2918243333	234	92.95	1	227	8	231	8.1e-48	157.1	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918243334	226	88.36	13	226	17	221	7.7e-48	157.2	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918243335	351	51.72	4	55	7	36	3.9e-02	11.9	COG5567	Predicted small periplasmic lipoprotein YifL (function unknown0	58
2918243336	142	91.95	1	142	7	143	4.9e-54	176.7	COG4125	Uncharacterized membrane protein	149
2918243337	293	96.01	3	292	5	293	5.6e-43	142.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918243338	627	84.94	165	627	65	425	1.8e-109	360.9	COG0840	Methyl-accepting chemotaxis protein	408
2918243339	261	93.82	3	261	10	252	5.4e-40	131.6	COG0730	Uncharacterized membrane protein YfcA	258
2918243340	179	89.47	2	178	4	190	3.7e-25	81.6	COG0406	Broad specificity phosphatase PhoE	208
2918243341	196	95.92	2	193	6	193	1.6e-33	109.9	COG3230	Heme oxygenase	196
2918243343	510	86.91	1	370	1	385	3.1e-50	165.9	COG3182	Uncharacterized iron-regulated membrane protein	442
2918243344	95	8.45	1	92	259	308	1.4e-02	8.6	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918243345	746	95.86	6	746	30	700	0.0e+00	745.6	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
2918243346	427	99.53	1	424	3	424	0.0e+00	464.8	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
2918243347	425	92.25	7	363	1	345	3.9e-56	185	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918243348	646	91.29	153	646	37	424	5.4e-98	323.5	COG0840	Methyl-accepting chemotaxis protein	408
2918243349	143	59.61	11	140	81	201	3.2e-31	102.8	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2918243350	235	97.35	1	231	1	220	9.3e-59	192.7	COG2135	Putative SOS response-associated peptidase YedK	226
2918243353	961	21.78	19	240	5	217	0.0e+00	266.6	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2918243353	961	71.98	238	956	263	966	0.0e+00	982.3	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2918243354	517	97.64	93	515	3	416	0.0e+00	513.5	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2918243355	161	87.35	6	157	19	163	1.6e-45	148.7	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2918243366	312	92	1	311	17	315	7.4e-87	285.8	COG0042	tRNA-dihydrouridine synthase	323
2918243367	308	99.01	5	306	2	302	1.5e-101	334.3	COG0176	Transaldolase	239
2918243369	160	86.32	2	116	5	105	1.4e-19	63.5	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918243370	394	99.18	12	393	3	367	4.7e-60	197.8	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2918243371	99	47.01	10	96	23	77	3.0e-04	15	COG3215	Tfp pilus assembly protein PilZ	117
2918243373	235	82.47	4	235	29	235	1.7e-81	267.4	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
2918243374	187	61.09	19	182	86	220	9.0e-11	35.3	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2918243376	276	95.62	1	133	6	136	5.7e-53	171.8	COG2904	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, N-terminal domain	137
2918243377	169	83.54	1	169	26	157	1.2e-39	130.2	COG4454	Uncharacterized copper-binding protein, cupredoxin-like subfamily	158
2918243378	226	99.14	1	225	1	230	4.0e-78	256.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918243379	455	91.12	85	453	29	387	2.3e-63	209.6	COG0642	Signal transduction histidine kinase	336
2918243380	414	100	1	414	1	410	0.0e+00	459.8	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2918243381	227	96.46	6	227	2	219	3.8e-81	266	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918243382	416	100	1	416	1	410	0.0e+00	496.4	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2918243384	240	95.94	1	240	10	269	1.2e-40	134.2	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2918243385	464	99.34	3	456	4	455	0.0e+00	458.6	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918243386	332	97.93	1	330	7	337	9.8e-90	295.1	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
2918243387	482	98.21	131	477	3	331	1.1e-108	357.7	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
2918243388	1149	98.95	5	1149	9	1136	0.0e+00	1503.6	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
2918243390	1103	62.78	435	1097	334	898	0.0e+00	560	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
2918243391	336	68.59	4	313	7	292	6.2e-95	312.9	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2918243393	235	92.34	1	210	13	205	5.2e-29	96.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918243394	202	99.01	1	202	1	201	2.7e-67	220.6	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2918243395	158	65.09	18	158	39	148	2.4e-40	132.4	COG5404	Cell division inhibitor SulA, prevents FtsZ ring assembly	169
2918243398	870	25.32	583	635	12	51	2.5e-41	23.5	COG0551	ssDNA-binding Zn-finger and Zn-ribbon domains of topoisomerase 1	140
2918243398	870	53.8	750	862	73	157	2.5e-41	33.7	COG0551	ssDNA-binding Zn-finger and Zn-ribbon domains of topoisomerase 1	140
2918243398	870	74.05	642	770	10	126	2.5e-41	75.7	COG0551	ssDNA-binding Zn-finger and Zn-ribbon domains of topoisomerase 1	140
2918243398	870	98.96	3	601	1	569	0.0e+00	728.4	COG0550	DNA topoisomerase IA	570
2918243399	83	61.29	1	83	40	115	8.9e-33	107.6	COG4728	Uncharacterized protein	124
2918243400	391	99.75	5	391	2	394	0.0e+00	450.2	COG0183	Acetyl-CoA acetyltransferase	392
2918243401	715	25.23	607	712	188	270	6.2e-117	18.9	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918243401	715	90.94	4	305	13	253	6.3e-56	183	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918243401	715	98.48	312	654	2	325	6.2e-117	374.8	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918243403	148	96.23	1	143	4	156	4.4e-30	99.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918243404	642	99.44	1	531	1	532	0.0e+00	582.9	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918243405	642	99.34	341	634	1	301	1.7e-59	196.6	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2918243407	267	96.3	1	267	4	263	6.2e-78	256.2	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
2918243408	311	90.23	175	309	6	125	2.6e-19	62.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918243408	311	95.15	4	164	4	160	5.5e-48	156.5	COG0835	Chemotaxis signal transduction protein	165
2918243410	296	55.73	11	282	166	374	2.0e-49	163	COG4585	Signal transduction histidine kinase	365
2918243411	219	99.05	3	216	2	210	1.1e-59	195.9	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918243412	295	95.36	5	291	13	300	4.4e-71	233.5	COG1597	Diacylglycerol kinase family enzyme	301
2918243413	414	93.4	1	396	19	400	9.5e-25	82.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918243414	408	98.03	8	407	6	404	0.0e+00	435.4	COG0303	Molybdopterin biosynthesis enzyme	404
2918243415	179	97.06	4	172	5	169	3.8e-60	196.4	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
2918243418	531	99.53	23	497	2	429	0.0e+00	481.5	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
2918243419	538	80	184	537	83	422	5.5e-101	333.4	COG0840	Methyl-accepting chemotaxis protein	408
2918243420	587	99.16	10	586	5	591	0.0e+00	537	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918243424	380	88.65	3	297	27	315	6.2e-64	207.4	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918243425	80	95	1	79	4	79	5.5e-27	88	COG0425	TusA-related sulfurtransferase	78
2918243426	310	95.11	7	310	12	264	4.2e-79	259.8	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
2918243427	466	95.07	17	463	22	445	0.0e+00	502.5	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2918243428	440	85.28	74	440	54	389	6.6e-44	145.6	COG0642	Signal transduction histidine kinase	336
2918243429	227	99.14	1	220	1	230	3.5e-76	249.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918243430	569	94.11	7	567	36	610	0.0e+00	556.7	COG4232	Thiol:disulfide interchange protein	569
2918243431	278	75.33	105	249	35	147	6.8e-16	53	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2918243432	252	93.17	1	251	6	237	6.1e-41	134.9	COG1651	Protein-disulfide isomerase	244
2918243433	357	99.16	1	352	1	355	0.0e+00	531.4	COG2933	23S rRNA C2498 (ribose-2'-O)-methylase RlmM	358
2918243434	913	99.43	5	912	4	868	0.0e+00	1319	COG1048	Aconitase A	861
2918243436	521	81.41	85	521	79	424	1.2e-101	335.4	COG0840	Methyl-accepting chemotaxis protein	408
2918243437	294	80.82	22	292	54	289	3.6e-50	165.3	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2918243440	381	95.63	1	381	12	405	2.8e-95	313.8	COG0004	Ammonia channel protein AmtB	409
2918243441	104	99.04	1	104	2	104	1.1e-33	110.5	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2918243442	124	88.55	1	124	13	128	3.0e-37	122	COG5393	Uncharacterized membrane protein YqjE	131
2918243444	443	97.39	1	440	11	420	5.7e-105	346.4	COG0232	dGTP triphosphohydrolase	412
2918243445	206	99.05	1	206	2	210	2.8e-54	178.3	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918243446	1192	29.6	277	446	15	154	1.1e-11	33.1	COG4623	Membrane-bound lytic murein transglycosylase MltF	473
2918243446	1192	39.32	62	270	45	230	1.1e-11	2.9	COG4623	Membrane-bound lytic murein transglycosylase MltF	473
2918243446	1192	59.2	1079	1169	8	81	1.9e-03	11.9	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918243446	1192	67.01	417	941	127	390	3.4e-65	215.6	COG0642	Signal transduction histidine kinase	336
2918243446	1192	94.74	953	1083	6	131	8.6e-33	104	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918243447	114	91.6	1	109	9	117	7.4e-39	127	COG3171	Uncharacterized conserved protein YggL, DUF469 family	119
2918243448	487	98.11	4	479	6	472	4.3e-126	415.7	COG2027	D-alanyl-D-alanine carboxypeptidase	470
2918243449	797	94.54	620	795	10	182	1.9e-51	167.8	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918243449	797	95.45	15	345	14	349	1.0e-26	87.6	COG3614	Extracellular (periplasmic) sensor domain CHASE1 (specificity unknown)	348
2918243450	730	14.44	574	656	254	308	0.0e+00	9.8	COG0116	23S rRNA G2445 N2-methylase RlmL	381
2918243450	730	98.43	3	390	3	377	0.0e+00	420.3	COG0116	23S rRNA G2445 N2-methylase RlmL	381
2918243452	71	98.18	1	55	1	54	5.9e-30	96.5	COG3130	Ribosome modulation factor	55
2918243453	341	92.9	39	341	4	291	2.6e-104	342.8	COG0167	Dihydroorotate dehydrogenase	310
2918243454	404	94.33	3	335	17	332	2.7e-76	251.1	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918243455	191	96.91	1	190	6	193	1.8e-65	214.4	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
2918243456	403	96.19	1	402	6	409	8.5e-116	381.4	COG2223	Nitrate/nitrite transporter NarK	417
2918243457	556	94.12	1	239	6	261	1.8e-36	118.8	COG0631	Serine/threonine protein phosphatase PrpC	262
2918243458	250	96.31	1	247	3	237	6.7e-87	285.5	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2918243459	344	89.95	125	342	19	197	3.5e-48	158.6	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918243460	188	90.32	16	188	14	181	8.8e-42	137.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918243461	274	30.7	3	113	29	133	2.4e-11	8.9	COG0668	Small-conductance mechanosensitive channel	316
2918243461	274	60.82	88	273	8	215	2.4e-11	34.9	COG0668	Small-conductance mechanosensitive channel	316
2918243463	331	95.43	11	331	15	327	2.8e-43	142.2	COG0598	Mg2+ and Co2+ transporter CorA	322
2918243464	163	76.42	1	162	13	174	5.1e-57	187.1	COG0684	Regulator of RNase E activity RraA	210
2918243465	330	84.75	20	312	13	262	1.0e-15	52.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918243466	791	99.11	1	789	3	782	0.0e+00	928.2	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
2918243467	272	98.53	1	272	3	271	3.2e-100	329.5	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
2918243469	1621	99.56	1	1614	6	1591	0.0e+00	2159.7	COG2902	NAD-specific glutamate dehydrogenase	1592
2918243471	413	20.23	320	399	141	192	1.3e-06	1.9	COG3319	Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase	257
2918243471	413	38.52	87	216	36	134	1.3e-06	19.2	COG3319	Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase	257
2918243472	319	96.06	1	319	12	328	3.1e-97	320	COG0714	MoxR-like ATPase	329
2918243473	314	61.39	17	309	160	415	6.0e-56	184.5	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2918243475	358	78.8	1	331	60	375	1.5e-29	97.5	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
2918243476	572	98.5	1	412	6	400	2.4e-15	50.4	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
2918243480	412	96.04	1	411	1	388	2.4e-57	189.3	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
2918243481	1214	39.94	798	1214	569	947	0.0e+00	208	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2918243481	1214	82.61	1	946	1	784	0.0e+00	251.2	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2918243482	197	94.42	1	197	1	203	2.7e-31	103.4	COG0625	Glutathione S-transferase	211
2918243483	381	99.13	26	381	3	345	2.4e-91	300.8	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
2918243485	791	99.18	8	780	4	732	0.0e+00	616	COG1033	Predicted exporter protein, RND superfamily	727
2918243486	342	90.56	12	342	29	335	1.5e-92	304.3	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
2918243487	885	99.54	1	879	4	866	0.0e+00	933.6	COG0308	Aminopeptidase N	859
2918243489	86	95.56	1	86	2	87	1.5e-32	106.2	COG3139	Uncharacterized conserved protein YeaC, DUF1315 family	90
2918243490	290	72.81	68	289	46	211	7.2e-37	121.4	COG0705	Membrane associated serine protease, rhomboid family	228
2918243492	296	99.65	5	289	1	284	1.7e-93	307.1	COG0061	NAD kinase	281
2918243493	329	97.92	20	321	5	287	1.5e-68	225.5	COG3782	Uncharacterized protein	289
2918243494	181	96.13	3	181	5	178	5.5e-54	176.9	COG3038	Cytochrome b561	181
2918243495	300	95.98	1	300	10	319	5.1e-39	127.6	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
2918243496	678	99.17	4	359	3	362	8.6e-118	387.8	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918243497	372	54.68	59	333	26	177	6.9e-13	40.4	COG0388	Predicted amidohydrolase	274
2918243498	346	84.09	199	345	15	125	3.0e-21	68.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918243504	257	98.88	9	254	3	267	2.9e-63	208.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918243505	403	97.98	13	403	7	395	0.0e+00	454	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2918243506	501	99.15	1	483	4	469	0.0e+00	636.5	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
2918243507	184	87.91	3	166	1	160	1.2e-43	143.4	COG1286	Uncharacterized membrane protein, required for colicin V production	182
2918243508	207	97.9	1	203	6	238	6.3e-40	130.7	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
2918243509	435	99.07	1	427	3	427	6.7e-127	418.3	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
2918243510	297	93.2	3	295	17	290	8.0e-129	423.2	COG0777	Acetyl-CoA carboxylase beta subunit	294
2918243511	206	99.04	3	206	2	208	1.8e-70	231.4	COG0135	Phosphoribosylanthranilate isomerase	208
2918243512	284	94.01	16	278	3	253	3.3e-87	286.4	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
2918243513	930	11.01	500	605	485	578	1.5e-104	28	COG3170	Tfp pilus assembly protein FimV	755
2918243513	930	17.45	1	151	12	160	1.5e-104	184.3	COG3170	Tfp pilus assembly protein FimV	755
2918243513	930	29.04	677	930	606	853	1.5e-104	45.9	COG3170	Tfp pilus assembly protein FimV	755
2918243513	930	38.06	130	496	166	490	1.5e-104	116.5	COG3170	Tfp pilus assembly protein FimV	755
2918243514	334	99.4	4	330	2	335	5.1e-84	276.9	COG0136	Aspartate-semialdehyde dehydrogenase	334
2918243515	370	99.7	1	368	1	335	1.5e-109	360.9	COG0136	Aspartate-semialdehyde dehydrogenase	334
2918243516	360	98.85	1	360	3	346	0.0e+00	458.1	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2918243517	254	51.05	10	201	50	171	7.9e-28	91.3	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918243518	214	96.89	1	212	1	187	4.4e-85	278.7	COG0066	3-isopropylmalate dehydratase small subunit	191
2918243519	477	99.3	1	472	3	428	0.0e+00	635	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
2918243520	292	97.34	1	291	2	294	8.3e-68	223.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918243521	1098	64.56	566	1097	217	644	9.9e-108	354.9	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918243522	147	96.58	1	140	6	146	5.3e-35	114.8	COG0071	Molecular chaperone IbpA, HSP20 family	146
2918243524	322	95.38	1	320	11	320	6.4e-82	269.7	COG0042	tRNA-dihydrouridine synthase	323
2918243526	144	92.09	5	141	5	132	2.3e-29	96.3	COG0824	Acyl-CoA thioesterase FadM	137
2918243527	277	23.39	168	271	214	282	2.3e-15	20	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918243527	277	40.34	26	193	14	132	2.3e-15	35	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918243528	179	87.56	1	179	13	195	7.7e-20	66.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918243535	493	97.71	1	472	9	477	0.0e+00	477.9	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2918243536	671	99.1	1	671	3	659	0.0e+00	1093.5	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
2918243537	398	99.75	3	398	2	396	0.0e+00	558.4	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
2918243539	186	92.72	1	186	6	196	1.8e-88	289.8	COG3816	Uncharacterized protein	205
2918243541	322	93.23	1	312	1	303	3.6e-75	247.1	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
2918243542	211	79.43	1	198	5	170	1.7e-26	88.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918243545	260	98.83	1	256	2	255	1.4e-85	281	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
2918243547	122	52.4	7	120	97	205	2.9e-30	99.9	COG0125	Thymidylate kinase	208
2918243550	743	47.46	272	566	157	315	1.0e-14	48.3	COG0582	Integrase	309
2918243552	445	70.15	87	413	81	315	6.3e-10	32.3	COG0582	Integrase	309
2918243555	369	53.57	189	242	19	48	2.6e-05	18.5	COG0401	Uncharacterized membrane protein YqaE, homolog of Blt101, UPF0057 family	56
2918243556	522	97.55	107	268	5	163	2.4e-37	122.6	COG3436	Transposase	157
2918243557	111	57.67	4	107	40	133	6.3e-15	49.5	COG3436	Transposase	157
2918243558	110	45.3	1	83	6	58	3.1e-14	47.7	COG2963	Transposase and inactivated derivatives	116
2918243560	553	11.77	22	132	20	98	2.6e-54	40.9	COG0210	Superfamily I DNA or RNA helicase	655
2918243560	553	16.54	369	548	529	639	2.6e-54	46.5	COG0210	Superfamily I DNA or RNA helicase	655
2918243560	553	37.7	126	413	192	444	2.6e-54	90	COG0210	Superfamily I DNA or RNA helicase	655
2918243561	651	79.12	1	480	2	471	4.4e-30	96.9	COG3593	Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains	581
2918243563	366	55.38	15	130	5	76	2.6e-08	26.7	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918243563	366	80.28	138	333	3	173	3.1e-31	102.1	COG2856	Zn-dependent peptidase ImmA, M78 family	213
2918243571	70	45.61	1	48	1	26	5.9e-04	14.1	COG5570	Uncharacterized protein	57
2918243573	125	49.04	1	120	3	104	4.1e-39	128.8	COG0125	Thymidylate kinase	208
2918243574	401	95.35	1	336	15	342	3.1e-105	346.3	COG1559	Cell division protein YceG, involved in septum cleavage	342
2918243575	273	95.09	1	270	5	275	5.3e-56	184.8	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2918243576	414	99.52	2	413	2	413	0.0e+00	537.7	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918243577	78	97.53	1	78	3	81	5.4e-32	104.2	COG0236	Acyl carrier protein	80
2918243578	246	99.63	1	245	1	267	3.2e-73	240.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918243579	312	98.24	2	312	3	336	1.6e-88	291.4	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
2918243580	336	97.64	3	336	4	334	3.9e-123	405.1	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
2918243581	60	98.25	1	56	1	56	2.1e-23	76.7	COG0333	Ribosomal protein L32	57
2918243582	175	96.65	1	172	6	178	6.0e-33	108.8	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
2918243583	192	97.94	1	192	3	192	1.0e-58	192.2	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
2918243584	329	91.88	19	324	11	304	1.3e-76	252.2	COG0616	Periplasmic serine protease, ClpP class	317
2918243585	225	97.75	3	218	4	220	8.3e-53	173.8	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918243586	318	98.29	10	306	5	291	6.6e-81	266.1	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2918243588	1095	98.98	1	486	4	487	0.0e+00	687.1	COG1530	Ribonuclease G or E	487
2918243589	71	39.8	8	67	19	57	3.5e-05	17.3	COG5416	Uncharacterized integral membrane protein	98
2918243590	339	96.94	3	339	4	288	2.7e-96	316.2	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
2918243591	154	97.97	1	151	3	147	1.6e-42	139.5	COG0394	Protein-tyrosine-phosphatase	139
2918243592	254	97.57	2	254	3	243	1.0e-104	343.4	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
2918243593	61	96.97	1	60	1	64	6.1e-25	81.3	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
2918243594	336	94.64	4	331	6	323	4.0e-109	358.9	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
2918243595	144	95.68	1	141	4	136	1.1e-31	104.1	COG0848	Biopolymer transport protein ExbD	137
2918243596	211	93.06	1	205	13	213	6.4e-52	171.1	COG0811	Biopolymer transport protein ExbB/TolQ	216
2918243597	738	89.84	424	735	29	302	1.7e-78	257.3	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
2918243597	738	90.74	2	425	16	446	3.1e-72	238.7	COG0658	Predicted membrane metal-binding protein	453
2918243598	208	94.57	1	178	4	177	5.8e-63	206	COG3216	Uncharacterized conserved protein, DUF2062 family	184
2918243599	259	82.94	8	258	46	288	4.7e-21	69.6	COG0842	ABC-type multidrug transport system, permease component	286
2918243600	310	99.35	1	303	2	305	2.9e-91	300.4	COG1131	ABC-type multidrug transport system, ATPase component	293
2918243601	207	95.81	2	207	1	206	1.2e-49	163.5	COG0625	Glutathione S-transferase	211
2918243602	815	18.55	483	625	323	396	1.6e-88	15.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918243602	815	88.97	75	483	6	360	1.6e-88	273.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918243605	179	95.19	1	179	8	185	6.3e-15	50	COG3539	Pilin (type 1 fimbria component protein)	184
2918243606	246	97.07	1	242	6	237	2.0e-67	221.3	COG3121	P pilus assembly protein, chaperone PapD	235
2918243616	799	94.99	5	788	42	837	0.0e+00	771.5	COG3188	Outer membrane usher protein FimD/PapC	835
2918243617	359	86.1	191	359	27	187	6.1e-27	88.1	COG3539	Pilin (type 1 fimbria component protein)	184
2918243625	160	91.41	2	160	12	160	1.8e-64	210.6	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
2918243626	295	96.54	1	295	6	284	9.9e-116	380.2	COG2607	Predicted ATPase, AAA+ superfamily	287
2918243627	771	72.84	13	518	103	389	3.7e-70	231.9	COG0642	Signal transduction histidine kinase	336
2918243627	771	93.98	645	770	3	127	3.5e-45	146.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918243628	162	97.53	1	162	3	160	5.1e-63	205.6	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
2918243629	131	90.07	3	131	3	129	1.4e-58	190.9	COG0229	Peptide methionine sulfoxide reductase MsrB	140
2918243630	403	99.49	7	402	2	395	5.4e-117	385.4	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918243631	295	94.55	1	294	11	305	1.4e-73	242.2	COG0501	Zn-dependent protease with chaperone function	302
2918243633	255	97.03	1	255	8	268	4.2e-90	296.2	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
2918243635	562	87.88	1	524	29	485	0.0e+00	489.3	COG0513	Superfamily II DNA and RNA helicase	513
2918243636	251	88.3	3	250	20	268	1.4e-41	136.5	COG0421	Spermidine synthase	282
2918243637	448	100	1	445	1	446	0.0e+00	761.3	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
2918243638	72	69.84	1	67	20	63	7.7e-19	61.7	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918243639	284	96.35	7	283	2	291	1.8e-53	176.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918243640	249	95.37	1	249	5	251	5.4e-46	151.4	COG0730	Uncharacterized membrane protein YfcA	258
2918243641	318	98.67	6	307	4	300	1.5e-62	206.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918243642	151	95.49	22	149	5	131	7.9e-27	88	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918243643	142	96.5	1	141	5	142	4.5e-50	163.9	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2918243646	189	97.71	1	131	3	130	6.8e-39	126.6	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
2918243647	377	98.65	2	377	3	367	0.0e+00	468.2	COG4394	Uncharacterized protein	370
2918243649	160	61.84	8	160	51	144	1.8e-09	31.4	COG0782	Transcription elongation factor, GreA/GreB family	151
2918243650	298	98.67	1	294	1	297	1.2e-68	226.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918243651	395	96.71	2	390	9	390	2.4e-39	129.1	COG2814	Predicted arabinose efflux permease, MFS family	394
2918243653	717	96.23	2	717	31	795	2.6e-67	222.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918243655	229	87.55	1	229	5	236	2.5e-40	132.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918243656	238	78.54	7	238	33	237	6.0e-45	147.9	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918243657	323	92.68	7	323	25	328	4.8e-66	217	COG0598	Mg2+ and Co2+ transporter CorA	322
2918243658	244	95.96	2	210	4	193	5.7e-44	144.5	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2918243659	266	83.54	110	266	4	140	1.1e-18	61.4	COG2010	Cytochrome c, mono- and diheme variants	150
2918243662	692	91.19	1	691	6	605	2.1e-107	354.5	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
2918243663	63	36.09	2	56	82	129	8.1e-04	14	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
2918243664	312	97.43	53	312	7	271	1.3e-64	212.9	COG0428	Zinc transporter ZupT	266
2918243666	174	40.3	104	173	93	225	6.5e-27	30.9	COG0666	Ankyrin repeat	235
2918243666	174	47.27	13	114	80	235	6.5e-27	63	COG0666	Ankyrin repeat	235
2918243668	178	94.48	1	177	1	171	4.1e-23	76.2	COG1791	Acireductone dioxygenase (methionine salvage), cupin superfamily	181
2918243669	384	48.83	194	381	8	194	1.2e-12	22.6	COG0477	MFS family permease	338
2918243669	384	53	3	201	5	207	1.2e-12	26	COG0477	MFS family permease	338
2918243670	363	98.11	2	361	2	364	0.0e+00	524.3	COG0082	Chorismate synthase	369
2918243671	319	88.14	25	290	17	276	1.8e-19	64.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918243673	302	98.95	7	295	2	285	1.4e-70	232	COG2890	Methylase of polypeptide chain release factors	280
2918243674	196	88.35	20	190	7	188	8.9e-32	104.2	COG1335	Nicotinamidase-related amidase	205
2918243676	186	95.65	1	182	7	182	3.7e-55	181.3	COG2840	DNA-nicking endonuclease, Smr domain	184
2918243677	181	90.86	1	181	17	195	1.2e-84	276.9	COG0302	GTP cyclohydrolase I	195
2918243678	123	83.75	41	117	5	71	3.8e-10	34	COG0695	Glutaredoxin	80
2918243679	200	93.02	2	200	2	201	2.1e-50	165.9	COG0625	Glutathione S-transferase	211
2918243680	396	96.28	1	396	10	397	0.0e+00	514.9	COG3135	Predicted benzoate:H+ symporter BenE	402
2918243684	253	99.25	3	251	1	266	1.5e-72	238.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918243685	333	97.94	1	333	6	338	0.0e+00	474	COG2130	NADPH-dependent curcumin reductase CurA	340
2918243686	167	74.71	1	160	2	128	1.5e-20	68.1	COG0645	Predicted kinase	170
2918243688	233	93.75	1	233	11	235	4.7e-79	259.5	COG0284	Orotidine-5'-phosphate decarboxylase	240
2918243690	108	48.1	6	107	83	158	9.4e-29	95.2	COG1555	DNA uptake protein ComE and related DNA-binding proteins	149
2918243691	263	93.58	1	259	11	258	3.1e-43	142.2	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2918243692	217	84.06	3	217	31	241	5.0e-74	243.3	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
2918243693	368	94.35	4	368	21	371	2.0e-87	287.9	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
2918243694	362	28.51	224	338	117	187	8.2e-29	15	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918243694	362	65.46	39	247	27	189	8.2e-29	80.8	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918243697	311	74.21	9	173	49	189	3.9e-39	128.3	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918243698	131	94.29	1	131	2	133	1.3e-32	107.2	COG0615	Glycerol-3-phosphate cytidylyltransferase, cytidylyltransferase family	140
2918243701	280	96.06	1	279	8	275	9.1e-130	426.1	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
2918243702	428	94.71	250	417	4	164	3.0e-60	196.5	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
2918243702	428	97.57	5	246	3	243	2.7e-86	282.7	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
2918243703	557	73.84	14	456	106	407	2.7e-34	113.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918243704	310	98.51	3	203	3	201	1.5e-77	253.7	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
2918243705	372	51.64	134	371	145	317	9.7e-06	17.1	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2918243706	670	93.92	5	652	8	640	0.0e+00	581.5	COG3563	Capsule polysaccharide export protein KpsC/LpsZ	671
2918243707	439	96.03	30	422	12	398	2.5e-101	333.5	COG3562	Capsule polysaccharide modification protein KpsS	403
2918243708	258	94.34	3	256	7	256	6.2e-40	131.2	COG0300	Short-chain dehydrogenase	265
2918243710	185	46.03	37	177	81	167	5.6e-12	39.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918243711	710	91.1	50	697	30	643	0.0e+00	577.2	COG3563	Capsule polysaccharide export protein KpsC/LpsZ	671
2918243713	151	94.12	9	144	3	130	4.2e-16	53.5	COG1943	REP element-mobilizing transposase RayT	136
2918243714	450	92.82	50	446	28	389	1.8e-118	389.8	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
2918243715	2500	62.6	2096	2291	8	161	7.4e-10	31.8	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2918243715	2500	77.78	2379	2454	11	73	3.0e-11	36.9	COG0236	Acyl carrier protein	80
2918243715	2500	95.77	1755	2077	14	330	6.5e-67	216.5	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918243715	2500	96.38	2	1307	7	1150	0.0e+00	1016.7	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2918243716	293	99.31	3	291	1	289	2.8e-124	408.2	COG1209	dTDP-glucose pyrophosphorylase	286
2918243717	298	99.29	1	296	1	280	9.9e-99	324.3	COG1091	dTDP-4-dehydrorhamnose reductase	281
2918243718	356	99.43	1	352	1	348	0.0e+00	537.6	COG1088	dTDP-D-glucose 4,6-dehydratase	340
2918243719	658	99.5	12	650	2	599	0.0e+00	726.6	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
2918243720	208	18.64	64	152	118	180	2.8e-20	42.8	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
2918243720	208	21.3	133	207	241	312	2.8e-20	35.2	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
2918243721	198	81.78	1	187	39	222	8.5e-79	258.2	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2918243722	169	90.96	1	164	16	176	1.5e-71	233.9	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
2918243723	391	97.33	2	389	9	373	3.5e-122	402.4	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2918243724	378	89	9	368	28	391	2.0e-32	107.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918243725	629	93.8	1	629	23	536	0.0e+00	441.4	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2918243726	358	81.91	2	358	73	407	3.9e-22	73.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918243727	305	80.51	1	301	3	254	5.0e-48	158.2	COG1216	Glycosyltransferase, GT2 family	305
2918243729	428	83.61	1	423	9	411	6.3e-38	124.9	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2918243730	341	97.82	16	341	5	318	4.4e-71	234.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918243731	421	95.87	1	420	10	427	0.0e+00	464.2	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
2918243732	353	94.57	1	346	14	344	5.1e-56	184.6	COG3765	LPS O-antigen chain length determinant protein, WzzB/FepE family	347
2918243733	484	94.74	4	478	3	416	1.1e-77	255.5	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
2918243734	79	74.49	1	79	20	92	1.2e-10	35.7	COG5416	Uncharacterized integral membrane protein	98
2918243735	99	97.87	1	94	2	93	2.8e-35	114.9	COG0776	Bacterial nucleoid DNA-binding protein	94
2918243736	558	98.18	1	549	2	541	0.0e+00	761.8	COG0539	Ribosomal protein S1	541
2918243737	228	95.98	2	227	4	218	7.3e-84	275.1	COG0283	Cytidylate kinase	222
2918243738	746	97.91	311	740	8	428	0.0e+00	477.9	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
2918243738	746	98.21	11	294	5	278	4.0e-83	272.7	COG0287	Prephenate dehydrogenase	279
2918243739	364	93.07	1	100	7	100	7.3e-25	80.4	COG1605	Chorismate mutase	101
2918243739	364	98.21	92	364	2	276	1.6e-101	333.5	COG0077	Prephenate dehydratase	279
2918243740	361	98.92	1	361	4	369	0.0e+00	487.2	COG1932	Phosphoserine aminotransferase	365
2918243741	921	99.51	1	886	4	812	0.0e+00	1182.3	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
2918243743	357	99.13	9	353	2	344	3.2e-130	428.4	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
2918243744	440	96.46	9	435	10	418	5.6e-120	395	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918243745	232	95.9	1	232	9	242	1.1e-102	336.9	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2918243746	223	98.65	1	219	2	220	1.7e-55	182.8	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918243747	246	97.01	9	246	3	262	9.9e-48	157.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918243748	261	94.21	10	257	4	231	2.5e-66	217.8	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
2918243749	818	62.75	185	813	223	638	6.8e-77	253.3	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918243750	593	98.31	5	593	7	588	0.0e+00	446.6	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918243751	210	98.11	2	210	2	209	2.8e-64	210.9	COG3531	Predicted protein-disulfide isomerase , contains CxxC motif	212
2918243752	310	97.08	1	304	1	299	8.8e-124	406.9	COG1054	Predicted sulfurtransferase	308
2918243753	98	98.89	1	84	1	89	4.1e-27	88.7	COG0271	Stress-induced morphogen (activity unknown)	90
2918243754	173	83.15	1	173	23	175	1.4e-36	120.7	COG3184	Uncharacterized protein	183
2918243755	464	99.35	1	461	3	461	0.0e+00	719.7	COG0114	Fumarate hydratase class II	462
2918243756	320	97.34	5	313	4	296	2.0e-32	106.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918243757	497	83.7	2	237	41	266	0.0e+00	167.9	COG2326	Polyphosphate kinase 2, PPK2 family	270
2918243757	497	84.81	239	494	38	266	0.0e+00	312	COG2326	Polyphosphate kinase 2, PPK2 family	270
2918243758	658	93.31	3	246	7	243	4.0e-75	246.5	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
2918243758	658	98.71	256	654	5	387	1.2e-65	216	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918243759	595	99.82	1	595	1	547	0.0e+00	473.2	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2918243760	581	87.3	31	283	21	185	2.6e-32	105.7	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918243760	581	93.71	274	573	3	300	4.3e-43	141.4	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
2918243761	394	96.9	10	356	3	346	2.3e-90	297.1	COG1363	Putative aminopeptidase FrvX	355
2918243762	75	98.61	1	71	1	71	1.7e-25	83.3	COG3089	Uncharacterized conserved protein YheU, UPF0270 family	72
2918243763	61	79.45	1	61	1	58	8.0e-23	74.9	COG1551	sRNA-binding carbon storage regulator CsrA	73
2918243765	110	96.33	1	108	3	107	8.4e-44	142.6	COG1742	Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily	109
2918243766	270	83.58	1	257	8	231	8.2e-56	184	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918243768	1065	80.2	398	800	75	390	2.0e-62	206.5	COG0642	Signal transduction histidine kinase	336
2918243768	1065	85.6	942	1060	8	114	8.9e-10	32.1	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918243768	1065	94.74	811	942	5	130	3.6e-30	95.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918243769	208	98.58	2	208	2	209	4.8e-56	184	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918243771	244	86.61	1	233	10	216	7.2e-09	27.7	COG3121	P pilus assembly protein, chaperone PapD	235
2918243773	159	35.59	1	146	2	85	1.8e-03	12.6	COG3637	Opacity protein and related surface antigens	199
2918243774	554	99.63	32	546	2	535	0.0e+00	699.8	COG4147	Na+(or H+)/acetate symporter ActP	529
2918243775	103	100	1	103	1	102	4.0e-42	136.8	COG3162	Uncharacterized membrane protein, DUF485 family	102
2918243776	282	93.44	1	282	13	297	3.9e-80	263.5	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
2918243777	515	79.34	58	305	64	305	4.9e-53	174.3	COG5309	Exo-beta-1,3-glucanase,  GH17 family	305
2918243779	432	37.64	31	275	70	200	2.8e-07	22.1	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
2918243780	271	80.08	48	271	29	229	3.3e-77	253.3	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
2918243781	311	99.35	1	307	2	307	1.8e-106	350.1	COG1560	Lauroyl/myristoyl acyltransferase	308
2918243782	252	99.13	15	252	1	227	1.0e-63	209.8	COG0850	Septum formation inhibitor MinC	219
2918243783	270	98.16	1	270	2	268	0.0e+00	433.5	COG2894	Septum formation inhibitor-activating ATPase MinD	272
2918243784	84	93.18	1	84	1	82	5.2e-35	113.7	COG0851	Septum formation topological specificity factor MinE	88
2918243785	211	72.26	1	211	82	292	1.6e-75	248.7	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2918243786	429	97.73	1	428	9	439	0.0e+00	535.5	COG1362	Aspartyl aminopeptidase	437
2918243787	55	10.58	2	52	330	373	7.4e-04	12.6	COG0814	Amino acid permease	415
2918243788	725	92.4	246	705	6	321	2.1e-53	176.2	COG0668	Small-conductance mechanosensitive channel	316
2918243791	237	95.4	1	236	11	238	2.5e-59	195.1	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918243792	353	98.67	54	350	2	298	2.4e-50	165.7	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918243793	268	65.9	1	267	40	354	1.3e-40	126.1	COG1524	Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily	450
2918243794	277	98.23	3	277	3	279	3.9e-114	375.2	COG4132	ABC-type uncharacterized transport system, permease component	282
2918243795	264	93.63	3	264	13	262	1.6e-58	192.3	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918243796	329	98.02	1	329	4	349	1.4e-119	393.6	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918243797	217	93.87	1	217	5	203	5.7e-55	180.4	COG0560	Phosphoserine phosphatase	212
2918243798	320	96.98	1	315	10	330	1.4e-78	258.9	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918243799	693	93.38	123	598	19	399	2.4e-122	402.6	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
2918243801	545	51.93	20	244	95	215	1.2e-09	29.8	COG2849	Antitoxin component YwqK of the YwqJK toxin-antitoxin module	230
2918243805	505	70.85	12	239	55	195	1.7e-36	120.9	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918243807	116	55.07	51	110	5	42	7.3e-05	16.6	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2918243808	146	75	23	138	17	103	1.1e-20	68.1	COG3339	Uncharacterized membrane protein YkvA, DUF1232 family	116
2918243809	246	98.06	23	229	5	206	1.5e-72	238.2	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
2918243810	310	98.67	7	307	2	298	1.7e-56	186.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918243811	309	79.55	158	303	21	125	5.8e-27	87.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918243812	447	93.11	6	437	15	433	3.6e-42	136.8	COG2271	Sugar phosphate permease	448
2918243813	233	78.02	12	227	58	270	5.1e-59	194.2	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918243814	254	91.42	4	248	4	248	2.3e-56	185.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918243815	316	95.72	1	316	13	325	1.3e-80	265.1	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918243816	120	97.2	10	120	2	105	1.8e-19	64	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2918243817	850	99.63	8	815	3	800	0.0e+00	999.2	COG1251	NAD(P)H-nitrite reductase, large subunit	793
2918243818	1342	92.96	781	1342	43	597	0.0e+00	535.7	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
2918243818	1342	94.81	1	717	42	809	0.0e+00	545.2	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918243819	258	98.71	1	255	4	309	1.4e-87	288.2	COG0024	Methionine aminopeptidase	255
2918243821	880	14.94	6	33	119	144	6.2e-04	9.6	COG1076	DnaJ-domain-containing proteins 1	174
2918243821	880	36.21	644	738	76	138	6.2e-04	3.2	COG1076	DnaJ-domain-containing proteins 1	174
2918243822	568	97.36	8	567	7	596	0.0e+00	462.6	COG0443	Molecular chaperone DnaK (HSP70)	579
2918243825	306	99.34	1	304	1	301	8.0e-128	420.3	COG2974	DNA recombination-dependent growth factor C	303
2918243826	321	98.77	1	318	3	322	5.1e-100	329.2	COG0385	Predicted Na+-dependent transporter	319
2918243828	105	97.17	1	105	2	104	7.8e-37	120.4	COG2076	Multidrug transporter EmrE and related cation transporters	106
2918243829	624	72.03	394	618	26	213	4.9e-38	124.7	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918243830	278	97.86	4	278	6	279	1.3e-60	199.6	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2918243831	424	49.61	222	422	15	204	2.0e-35	31.2	COG0477	MFS family permease	338
2918243831	424	75.72	13	263	2	291	2.0e-35	91.6	COG0477	MFS family permease	338
2918243832	243	97.49	3	242	6	238	8.1e-63	206.3	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918243833	469	95.67	3	462	9	450	0.0e+00	494.2	COG1113	L-asparagine transporter and related permeases	462
2918243834	115	86.03	4	115	18	134	1.5e-23	77.6	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918243835	238	99.16	2	238	2	236	9.7e-96	313.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918243836	257	99.61	1	253	2	254	3.5e-100	328.8	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918243837	415	97.21	3	378	8	321	1.3e-93	307.7	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918243838	312	98.34	4	311	3	298	2.5e-89	294.2	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918243839	382	95.9	11	380	4	354	5.5e-79	260.1	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918243840	246	96.68	2	243	5	237	8.0e-56	183.5	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918243841	241	95.85	4	241	6	236	3.1e-53	174.9	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918243842	482	98.33	12	482	4	474	0.0e+00	599.8	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918243843	561	99.28	8	559	2	552	0.0e+00	583.2	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918243844	398	96.13	6	390	3	375	3.0e-65	215.3	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918243845	270	60.75	1	212	3	197	2.6e-32	106.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918243846	400	98.74	6	399	3	393	4.0e-119	392.5	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918243847	550	97.52	1	550	5	555	1.1e-122	404.3	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
2918243848	691	99.26	4	691	3	676	0.0e+00	548.5	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2918243849	251	96.34	7	241	9	245	1.4e-68	225.5	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2918243850	249	98.51	1	247	4	267	2.2e-53	175.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918243851	218	86.12	16	217	6	185	5.0e-22	73.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918243852	1158	66.75	729	1022	130	392	6.8e-59	194.9	COG0642	Signal transduction histidine kinase	336
2918243852	1158	93.23	1027	1158	6	129	2.6e-16	50.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918243852	1158	97.6	1	543	2	489	1.6e-98	324.6	COG0591	Na+/proline symporter	493
2918243853	490	95.55	24	489	5	433	2.4e-122	403	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
2918243854	111	28.1	19	110	79	171	3.9e-10	33.4	COG0790	TPR repeat	292
2918243858	423	99.1	1	423	5	444	7.0e-106	348.8	COG2067	Long-chain fatty acid transport protein	440
2918243859	311	98.01	2	306	3	297	1.6e-66	219.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918243861	184	89.51	25	182	16	160	1.9e-49	161.4	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
2918243863	400	45.69	2	204	21	195	7.9e-19	36.7	COG0477	MFS family permease	338
2918243863	400	49.87	210	398	4	194	7.9e-19	32.1	COG0477	MFS family permease	338
2918243864	134	90.98	10	134	7	127	4.9e-21	69.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918243866	246	97.59	1	245	4	246	1.3e-50	166.9	COG0368	Cobalamin synthase	246
2918243867	188	90.91	1	188	3	192	9.4e-49	160.3	COG0406	Broad specificity phosphatase PhoE	208
2918243868	351	95.14	1	350	6	338	6.1e-103	338.6	COG2038	NaMN:DMB phosphoribosyltransferase	347
2918243869	173	99.43	1	170	1	174	2.7e-63	207.2	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
2918243870	484	99.59	1	483	1	484	0.0e+00	644	COG1492	Cobyric acid synthase	486
2918243871	330	95.57	1	330	15	359	5.0e-65	214.1	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2918243872	302	95.94	1	301	6	312	1.8e-102	336.9	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
2918243873	216	91.2	10	202	2	198	2.5e-33	110	COG0778	Nitroreductase	207
2918243874	431	98.9	8	431	2	449	2.2e-130	429.8	COG1797	Cobyrinic acid a,c-diamide synthase	451
2918243875	203	98.48	6	203	3	197	1.4e-76	251.1	COG2109	ATP:corrinoid adenosyltransferase	198
2918243877	352	99.14	1	352	1	345	1.2e-123	406.9	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2918243878	438	97.58	1	438	9	411	4.8e-123	405.6	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2918243879	178	53.82	8	166	115	248	2.3e-48	159.9	COG0791	Cell wall-associated hydrolase, NlpC family	197
2918243881	234	55.66	1	234	93	333	3.2e-52	172.3	COG0593	Chromosomal replication initiation ATPase DnaA	408
2918243882	358	93.89	1	355	14	351	5.6e-81	266.6	COG0628	Predicted PurR-regulated permease PerM	355
2918243883	358	91.25	1	351	11	323	2.1e-71	235.1	COG3249	Uncharacterized protein	343
2918243885	352	98.84	4	347	3	343	0.0e+00	487.8	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
2918243886	217	97.5	6	205	2	196	1.5e-80	263.8	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
2918243890	179	81.4	1	179	41	215	3.1e-59	194.8	COG3122	Uncharacterized conserved protein YaiL, DUF2058 family	215
2918243891	277	52.05	1	271	234	487	1.3e-70	233.2	COG3956	Uncharacterized conserved protein YabN, contains tetrapyrrole methylase and MazG-like pyrophosphatase domain	488
2918243892	746	99.45	10	743	4	723	0.0e+00	863.2	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2918243893	452	99.54	24	445	3	436	8.1e-123	404.9	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
2918243894	299	98.68	4	294	4	301	9.1e-107	350.9	COG0031	Cysteine synthase	300
2918243897	466	80.2	7	450	65	380	1.1e-49	164	COG0642	Signal transduction histidine kinase	336
2918243898	238	98.71	9	236	2	230	1.3e-67	221.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918243899	918	85.28	112	518	56	391	3.9e-82	271.3	COG0642	Signal transduction histidine kinase	336
2918243899	918	93.98	663	914	3	127	1.2e-40	127	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918243900	329	98.78	1	329	1	323	1.1e-103	341	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918243902	134	75.17	1	132	26	134	2.4e-30	99.8	COG3187	Heat shock protein HslJ	142
2918243903	155	62.67	6	152	36	129	1.8e-13	45.4	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2918243904	117	96.58	2	117	4	116	8.3e-38	123.6	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2918243905	201	97.18	4	198	5	211	2.0e-40	133.3	COG0655	Multimeric flavodoxin WrbA	207
2918243906	137	93.13	1	136	8	129	1.1e-38	126.7	COG3308	Uncharacterized membrane protein	131
2918243907	223	93.62	9	215	12	187	1.2e-47	156.3	COG2818	3-methyladenine DNA glycosylase Tag	188
2918243908	274	82.79	10	271	1	255	9.3e-72	235.9	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
2918243910	164	96.15	3	161	4	153	7.3e-50	162.9	COG3091	Predicted Zn-dependent metalloprotease, SprT family	156
2918243911	440	95.69	3	424	4	403	0.0e+00	524.2	COG1301	Na+/H+-dicarboxylate symporter	415
2918243912	448	83.5	83	448	59	387	4.4e-42	139.6	COG0642	Signal transduction histidine kinase	336
2918243913	225	99.14	1	223	1	230	4.3e-77	252.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918243914	201	98.31	2	201	5	236	6.2e-09	23.6	COG3637	Opacity protein and related surface antigens	199
2918243915	263	98.31	21	263	3	235	3.6e-56	184.5	COG0412	Dienelactone hydrolase	236
2918243916	233	97.37	8	233	6	227	3.9e-65	213.9	COG2977	4'-phosphopantetheinyl transferase EntD (siderophore biosynthesis)	228
2918243917	535	85.03	13	535	56	390	1.3e-63	208.4	COG0642	Signal transduction histidine kinase	336
2918243918	234	98.71	6	231	2	230	7.2e-82	268.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918243919	959	5.11	75	142	31	69	0.0e+00	9.2	COG0209	Ribonucleotide reductase alpha subunit	696
2918243919	959	97.64	202	959	11	755	0.0e+00	634.2	COG0209	Ribonucleotide reductase alpha subunit	696
2918243920	416	95.32	75	416	14	339	4.3e-99	326	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
2918243921	258	78.03	133	257	20	122	1.4e-23	77.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918243922	303	97.01	6	295	5	296	7.3e-35	114.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918243924	268	60.75	4	228	3	197	7.9e-30	98.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918243925	297	93.85	1	295	18	307	3.2e-79	260.6	COG3386	Sugar lactone lactonase YvrE	307
2918243926	323	96.39	1	323	10	329	1.1e-101	334.9	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918243927	175	84.18	1	174	5	153	8.0e-40	130.5	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918243928	426	99.21	46	426	2	377	0.0e+00	465.7	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918243929	311	96.35	16	311	7	296	2.6e-31	103.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918243930	291	94.25	1	288	14	308	3.6e-42	139.1	COG2017	Galactose mutarotase or related enzyme	308
2918243931	299	98.67	2	298	3	299	3.6e-69	228.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918243932	677	87.31	325	610	3	236	1.4e-65	215.4	COG1018	Ferredoxin-NADP reductase	266
2918243932	677	98.85	12	248	1	172	6.8e-27	88.2	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2918243933	209	93.49	5	205	2	202	2.4e-45	149.3	COG0625	Glutathione S-transferase	211
2918243934	184	70.05	3	182	12	163	2.4e-24	80.7	COG3318	Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C motif	216
2918243935	181	79.26	3	180	4	175	1.7e-28	94.3	COG3318	Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C motif	216
2918243936	329	91.06	1	327	20	345	4.3e-79	260.3	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
2918243939	298	92.81	9	288	2	259	4.4e-63	207.3	COG0388	Predicted amidohydrolase	274
2918243940	547	96.94	1	544	2	539	0.0e+00	548.4	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918243946	298	95.09	19	278	9	260	3.2e-62	204.1	COG2116	Formate/nitrite transporter FocA, FNT family	265
2918243947	364	95.09	76	341	6	257	1.1e-62	204.1	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
2918243948	357	93.99	166	344	10	181	3.5e-42	138.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918243949	294	93.75	1	293	12	341	3.4e-85	278.3	COG1566	Multidrug resistance efflux pump	352
2918243952	662	95.48	6	661	4	658	5.9e-116	382.6	COG1289	Uncharacterized membrane protein YccC	674
2918243958	948	77.44	65	859	45	741	3.0e-62	204.7	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
2918243959	754	71.04	156	727	176	646	5.3e-109	359.3	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918243960	295	99.3	6	292	3	286	4.6e-92	302.6	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918243961	101	96.91	5	100	2	95	3.3e-22	72.8	COG5626	Uncharacterized protein	97
2918243962	371	96.17	10	371	5	356	1.1e-90	298.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918243963	307	98.67	3	306	4	300	4.3e-98	322.9	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918243964	418	96.9	88	416	8	320	1.6e-105	347.4	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918243965	255	99.61	1	254	2	254	4.5e-113	371.1	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918243966	233	98.73	1	233	3	236	3.9e-100	328.3	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918243968	224	90.6	79	223	6	140	1.0e-26	87.6	COG3650	Uncharacterized membrane protein	149
2918243969	537	99.18	5	534	2	483	0.0e+00	570.7	COG2509	Uncharacterized FAD-dependent dehydrogenase	486
2918243970	154	100	1	154	1	154	3.6e-53	174.1	COG3133	Outer membrane lipoprotein SlyB	154
2918243971	215	99.53	1	215	2	214	3.1e-89	292.4	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
2918243972	325	91.46	19	234	17	198	2.5e-27	91	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918243973	381	87.38	7	381	40	392	4.0e-56	185.2	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918243975	714	97.05	10	714	4	661	0.0e+00	497.1	COG1199	Rad3-related DNA helicase	654
2918243976	154	93.79	1	154	5	155	5.8e-45	147.5	COG5615	Uncharacterized membrane protein	161
2918243978	91	95.6	1	90	1	87	1.1e-22	74.5	COG3776	Uncharacterized conserved protein YhhL, DUF1145 family	91
2918243979	239	61.31	73	239	75	196	1.6e-41	137.1	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918243980	230	57.29	40	230	84	197	2.1e-44	146.6	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918243982	158	98.01	1	154	3	150	3.1e-58	190.7	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
2918243983	157	91.3	1	157	15	161	6.0e-22	72.5	COG5608	LEA14-like dessication related protein	161
2918243984	67	13.82	13	67	187	216	2.6e-09	31.8	COG3318	Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C motif	216
2918243985	812	98.07	9	806	10	773	0.0e+00	521.7	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
2918243986	338	12.36	246	329	375	428	7.7e-32	11.3	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
2918243986	338	55.61	2	214	22	264	7.7e-32	90	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
2918243987	552	96.95	60	552	14	490	6.8e-78	256.8	COG1793	ATP-dependent DNA ligase	444
2918243988	371	86.97	8	365	41	327	2.8e-54	178.4	COG3608	Predicted deacylase	331
2918243989	831	96.88	2	821	11	848	0.0e+00	556.4	COG1201	Lhr-like helicase	814
2918243990	219	85.36	8	218	6	209	6.5e-34	111.6	COG1407	Metallophosphoesterase superfamily enzyme	235
2918243992	188	97.84	2	188	2	182	2.5e-67	220.6	COG0717	Deoxycytidine triphosphate deaminase	183
2918243993	69	97.01	4	69	2	66	1.5e-31	102.7	COG1278	Cold shock protein, CspA family	67
2918243994	364	93.71	37	316	18	285	5.0e-93	305.4	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918243995	679	79.58	560	679	8	120	2.8e-38	124.5	COG0073	tRNA-binding EMAP/Myf domain	123
2918243995	679	99.28	1	548	4	558	0.0e+00	664	COG0143	Methionyl-tRNA synthetase	558
2918243996	182	79.27	1	182	39	191	1.1e-17	57	COG4657	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfA subunit	193
2918243997	323	93.79	3	321	15	331	3.4e-96	316.9	COG4658	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfD subunit	338
2918243998	199	98.97	1	191	2	194	2.5e-37	123.1	COG4659	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit	195
2918243999	174	9.91	135	165	185	205	9.8e-10	7.4	COG4660	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfE subunit	212
2918243999	174	61.79	3	139	24	154	9.8e-10	29.1	COG4660	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfE subunit	212
2918244000	212	98.58	1	211	2	209	6.0e-88	287.9	COG0177	Endonuclease III	211
2918244002	208	98.58	1	208	2	209	1.5e-56	185.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918244004	405	98.76	1	405	3	400	0.0e+00	577.1	COG0137	Argininosuccinate synthase	403
2918244005	318	56.28	101	281	85	196	3.5e-28	93.3	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918244006	348	99.42	1	344	2	343	0.0e+00	520.9	COG0418	Dihydroorotase	344
2918244007	220	11.54	22	220	427	593	3.2e-20	65.7	COG2176	DNA polymerase III, alpha subunit (gram-positive type)	1444
2918244008	200	98.96	1	196	1	190	3.8e-75	245.9	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
2918244009	73	98.41	1	63	1	62	8.8e-24	78	COG2906	Bacterioferritin-associated ferredoxin	63
2918244010	157	99.36	1	157	1	156	7.1e-72	234.8	COG2193	Bacterioferritin (cytochrome b1)	157
2918244011	111	97.14	1	103	3	104	4.5e-46	149.4	COG0278	Glutaredoxin-related protein	105
2918244012	702	94.2	2	702	46	808	9.4e-107	350.7	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918244013	306	98.71	1	300	4	310	5.8e-114	375	COG0078	Ornithine carbamoyltransferase	310
2918244014	369	98.58	2	347	5	352	3.2e-111	366.3	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918244015	156	98.06	1	155	1	152	1.0e-53	175.5	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
2918244016	283	96.73	7	260	7	243	1.9e-79	260.7	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
2918244017	499	99	3	497	4	499	0.0e+00	786.2	COG0554	Glycerol kinase	499
2918244018	251	99.21	1	251	1	252	5.8e-84	276	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2918244019	512	93.85	8	512	13	516	0.0e+00	578.7	COG0578	Glycerol-3-phosphate dehydrogenase	532
2918244020	307	96.11	1	283	9	280	4.7e-57	187.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918244021	248	92.98	3	241	15	226	3.3e-69	227.3	COG0765	ABC-type amino acid transport system, permease component	222
2918244022	223	92.54	1	223	15	225	3.1e-65	214.4	COG0765	ABC-type amino acid transport system, permease component	222
2918244023	244	99.17	1	242	2	241	5.7e-112	367.1	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918244024	634	98.68	16	625	7	602	0.0e+00	632.9	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2918244025	442	97.43	2	442	5	459	0.0e+00	567.6	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918244026	111	99.1	1	111	2	111	2.2e-51	167.4	COG3136	Uncharacterized membrane protein, GlpM family	111
2918244027	331	97.29	29	321	6	292	5.6e-39	128.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918244028	305	96.68	2	299	2	292	3.0e-58	192.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918244029	137	83.72	1	137	18	161	9.8e-22	72.2	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918244030	87	97.33	1	86	1	73	1.7e-28	93.1	COG0254	Ribosomal protein L31	75
2918244031	539	19.43	26	145	18	112	8.2e-121	19.3	COG0069	Glutamate synthase domain 2	485
2918244031	539	64.83	144	492	171	487	8.2e-121	377.5	COG0069	Glutamate synthase domain 2	485
2918244032	1011	99.16	40	936	2	708	2.6e-100	331.2	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2918244033	177	63.5	18	171	4	90	4.1e-25	82.3	COG1695	DNA-binding transcriptional regulator, PadR family	138
2918244034	253	95.49	1	252	9	262	5.5e-71	233.4	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
2918244036	73	50.74	1	73	10	78	2.2e-33	109.9	COG4628	Uncharacterized conserved protein, DUF2132 family	136
2918244037	683	24.65	2	210	42	237	2.0e-72	80.7	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918244037	683	59.75	196	683	321	795	2.0e-72	164.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918244038	448	94.99	2	448	23	439	0.0e+00	517.6	COG3659	Carbohydrate-selective porin OprB	439
2918244039	803	99.48	12	803	4	772	0.0e+00	1137.2	COG4993	Glucose dehydrogenase	773
2918244040	806	97.83	28	806	9	775	0.0e+00	950.6	COG0466	ATP-dependent Lon protease, bacterial type	782
2918244041	130	86.73	16	130	15	112	8.0e-24	78.3	COG5513	Predicted secreted protein	113
2918244042	247	55.91	7	244	54	209	6.1e-10	34.1	COG0500	SAM-dependent methyltransferase	257
2918244043	318	64.87	55	313	42	222	1.1e-10	36.4	COG0500	SAM-dependent methyltransferase	257
2918244046	387	21.34	266	353	22	72	5.7e-03	8.3	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2918244046	387	59	88	260	34	174	5.7e-03	5.1	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2918244048	224	99.57	1	224	1	231	4.0e-83	272.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918244049	461	92.64	24	461	21	385	5.2e-72	237.8	COG0642	Signal transduction histidine kinase	336
2918244050	246	99.18	7	246	1	241	2.6e-102	335.6	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
2918244051	227	93.65	1	227	8	243	1.6e-43	143.2	COG1381	Recombinational DNA repair protein (RecF pathway)	251
2918244052	300	98.32	4	299	3	295	2.0e-120	395.7	COG1159	GTPase Era, involved in 16S rRNA processing	298
2918244053	229	95.76	1	228	7	232	7.4e-78	255.3	COG0571	dsRNA-specific ribonuclease	235
2918244054	284	78.98	50	267	7	145	5.5e-34	110.6	COG0681	Signal peptidase I	166
2918244055	599	98.84	1	599	6	601	0.0e+00	1009.8	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
2918244056	479	26.03	380	479	264	358	0.0e+00	45.1	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918244056	479	90.14	7	372	36	364	0.0e+00	405.1	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918244057	320	97.5	1	317	8	319	4.2e-83	273.5	COG3026	Negative regulator of sigma E activity	320
2918244058	196	100	1	196	1	213	8.0e-36	113.9	COG3073	Negative regulator of sigma E activity	213
2918244059	193	95.7	6	193	2	179	4.0e-53	174.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918244060	534	97.31	1	534	4	509	0.0e+00	703.1	COG0029	Aspartate oxidase	518
2918244062	84	85.11	1	84	11	90	5.3e-27	88.1	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
2918244063	313	94.16	1	308	12	301	1.5e-67	222.6	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
2918244064	268	83.39	1	256	1	241	1.5e-54	179	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
2918244065	459	79.44	19	459	73	385	4.0e-62	205.4	COG0642	Signal transduction histidine kinase	336
2918244066	223	99.14	1	222	1	230	2.3e-74	244	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918244068	326	98.12	1	326	6	318	4.6e-110	362.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918244070	504	98.81	1	504	1	498	0.0e+00	679.6	COG3333	TctA family transporter	504
2918244071	343	97.73	1	343	8	351	3.6e-90	296.7	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
2918244072	230	99.1	7	228	2	221	1.7e-98	323.2	COG0692	Uracil DNA glycosylase	223
2918244073	369	96.23	2	337	11	265	4.9e-69	226.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918244075	496	93.99	309	488	10	181	1.4e-54	178.8	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918244077	230	95.53	1	230	3	237	2.5e-63	208	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2918244078	294	94.24	1	274	5	282	1.6e-22	74.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918244080	355	96.31	20	341	9	269	1.7e-53	176.3	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2918244082	421	55.13	8	318	67	281	6.6e-07	22.7	COG2232	Predicted ATP-dependent carboligase, ATP-grasp superfamily	389
2918244084	205	94.37	3	205	12	212	7.5e-35	115	COG3762	Uncharacterized membrane protein	213
2918244085	762	99.76	40	458	1	416	7.3e-114	375.4	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2918244086	585	99.01	5	581	5	602	0.0e+00	599.7	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2918244087	441	98.29	1	441	5	463	0.0e+00	546.5	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918244088	439	46.48	239	432	9	186	2.8e-38	26.6	COG0477	MFS family permease	338
2918244088	439	63.19	23	274	3	244	2.8e-38	107.7	COG0477	MFS family permease	338
2918244089	34	5.46	1	34	499	531	1.8e-09	31.3	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2918244090	440	47.78	242	437	8	190	6.7e-35	28.2	COG0477	MFS family permease	338
2918244090	440	63.19	22	279	7	248	6.7e-35	92.4	COG0477	MFS family permease	338
2918244092	201	94.05	3	197	8	181	7.7e-45	147.1	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918244094	98	83.84	5	97	4	86	1.3e-13	45	COG1359	Quinol monooxygenase YgiN	100
2918244095	306	75.76	183	304	21	120	1.5e-27	89.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918244096	545	95.86	1	543	2	533	0.0e+00	458.3	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918244097	291	98.01	5	291	2	296	4.6e-57	188.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918244099	289	97.59	3	289	5	288	2.6e-76	250.9	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
2918244100	483	48.56	260	481	8	193	8.2e-47	6.1	COG0477	MFS family permease	338
2918244100	483	77.55	8	305	4	300	8.2e-47	151.4	COG0477	MFS family permease	338
2918244101	210	89	1	208	5	190	2.4e-27	91.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918244102	384	98.21	1	364	6	388	5.5e-66	217.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918244103	1050	99.7	1	1029	2	1012	0.0e+00	1223.5	COG0841	Multidrug efflux pump subunit AcrB	1009
2918244104	484	99.57	12	477	2	459	0.0e+00	458.7	COG1538	Outer membrane protein TolC	457
2918244113	670	93.94	1	578	19	561	0.0e+00	556.6	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2918244114	172	97.47	1	172	1	154	4.2e-54	177.2	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2918244116	316	98.01	1	303	1	295	1.7e-53	176.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918244117	174	95	1	174	1	171	2.5e-63	207.3	COG4539	Uncharacterized membrane protein YGL010W	180
2918244118	130	96.77	8	128	2	121	2.5e-37	122.3	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918244119	263	95.59	4	263	12	293	3.3e-32	106.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918244120	454	99.32	10	448	2	437	0.0e+00	459.9	COG0015	Adenylosuccinate lyase	438
2918244121	429	46.74	230	426	8	186	1.1e-37	27	COG0477	MFS family permease	338
2918244121	429	74.15	12	273	7	290	1.1e-37	102.4	COG0477	MFS family permease	338
2918244122	400	100	1	400	1	394	0.0e+00	468.4	COG0183	Acetyl-CoA acetyltransferase	392
2918244124	448	48.3	259	445	5	189	3.9e-40	34.8	COG0477	MFS family permease	338
2918244124	448	58.75	27	269	2	226	3.9e-40	102.2	COG0477	MFS family permease	338
2918244125	289	98.78	44	289	2	244	1.3e-71	234.8	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918244127	490	98.87	12	489	3	352	1.5e-122	403.2	COG0306	Phosphate/sulfate permease	326
2918244128	491	85.1	19	484	5	461	1.8e-75	248.9	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
2918244129	624	81.88	132	624	78	425	2.2e-107	354.1	COG0840	Methyl-accepting chemotaxis protein	408
2918244130	370	98.04	1	363	6	406	3.7e-42	139.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918244131	254	97.86	6	254	2	230	1.8e-73	241.2	COG3233	Predicted deacetylase	233
2918244132	331	90.74	1	325	23	316	1.1e-29	95.8	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2918244133	283	97.91	1	283	6	286	1.1e-126	416.7	COG0788	Formyltetrahydrofolate hydrolase	287
2918244135	476	98.11	1	471	9	474	0.0e+00	662	COG2925	Exonuclease I	475
2918244138	484	99.58	1	478	3	478	0.0e+00	591	COG0469	Pyruvate kinase	477
2918244139	307	74.76	10	88	19	95	7.5e-16	51.2	COG0633	Ferredoxin	102
2918244139	307	75.88	94	298	23	217	3.2e-27	89.3	COG0543	NAD(P)H-flavin reductase	252
2918244140	507	98.38	315	500	2	183	6.4e-75	244.5	COG1838	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain	184
2918244140	507	98.66	1	303	2	296	3.4e-119	391.5	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
2918244141	196	73.46	11	185	36	154	1.2e-08	30	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918244142	132	40.88	1	102	13	68	5.6e-06	20.5	COG4319	Ketosteroid isomerase homolog	137
2918244145	226	59.41	7	190	10	151	2.5e-14	47.2	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918244146	441	84.01	37	427	56	386	5.6e-51	168.6	COG0642	Signal transduction histidine kinase	336
2918244147	227	99.14	1	224	1	230	3.3e-74	243.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918244148	547	98.55	1	536	1	542	0.0e+00	619	COG0459	Chaperonin GroEL (HSP60 family)	524
2918244149	97	98.96	1	97	1	95	1.4e-39	128.7	COG0234	Co-chaperonin GroES (HSP10)	96
2918244151	153	90.06	1	153	2	146	2.5e-45	148.4	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
2918244152	243	97.57	2	240	5	245	1.2e-61	202.5	COG0748	Putative heme iron utilization protein	245
2918244154	133	96.12	25	128	4	102	7.9e-32	103.8	COG3695	Alkylated DNA nucleotide flippase Atl1, participates in nucleotide excision repair, Ada-like DNA-binding domain	103
2918244155	515	48.83	307	509	8	194	3.0e-14	17.1	COG0477	MFS family permease	338
2918244155	515	81.72	11	313	3	315	3.0e-14	36.9	COG0477	MFS family permease	338
2918244156	413	95.19	7	412	14	389	3.7e-20	65.7	COG2814	Predicted arabinose efflux permease, MFS family	394
2918244157	280	83.92	4	279	35	321	1.2e-68	226.1	COG0668	Small-conductance mechanosensitive channel	316
2918244158	161	98.18	1	161	4	165	4.8e-66	216.4	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
2918244159	305	96.12	3	302	2	298	5.2e-66	217.2	COG1893	Ketopantoate reductase	307
2918244160	678	27.16	117	266	69	175	2.3e-57	5.3	COG0642	Signal transduction histidine kinase	336
2918244160	678	84.52	268	672	60	392	2.3e-57	189.9	COG0642	Signal transduction histidine kinase	336
2918244161	188	97.84	2	186	3	183	2.1e-63	207.6	COG2096	Cob(I)alamin adenosyltransferase	184
2918244162	314	84.88	1	136	12	157	2.3e-23	77	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918244162	314	88.63	124	314	5	191	1.6e-35	116.3	COG0352	Thiamine monophosphate synthase	211
2918244163	210	92.09	5	210	5	202	6.9e-32	105.4	COG0625	Glutathione S-transferase	211
2918244164	405	97.28	7	405	12	405	0.0e+00	497.5	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
2918244165	913	99.64	2	906	4	840	0.0e+00	1265.1	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
2918244166	133	49.72	20	130	83	172	6.8e-10	33.6	COG5389	Uncharacterized protein	181
2918244167	303	99	1	301	1	298	0.0e+00	433.7	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
2918244168	398	91.38	4	357	11	328	0.0e+00	454.3	COG0206	Cell division GTPase FtsZ	338
2918244169	420	98.85	1	420	5	433	0.0e+00	523.5	COG0849	Cell division ATPase FtsA	418
2918244170	285	96.68	7	281	6	267	3.2e-56	184.7	COG1589	Cell division septal protein FtsQ	269
2918244171	318	98.43	16	313	2	314	8.8e-100	328.2	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
2918244172	484	98.7	10	471	3	457	0.0e+00	595.4	COG0773	UDP-N-acetylmuramate-alanine ligase	459
2918244173	359	99.44	6	359	1	356	1.6e-119	393.7	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
2918244174	404	95.29	9	389	13	376	2.2e-118	389.6	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
2918244175	448	97.78	3	448	8	447	0.0e+00	466.7	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
2918244176	360	98.77	20	360	2	323	2.3e-113	372.9	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2918244177	455	99.12	3	450	3	452	0.0e+00	486.2	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
2918244178	495	97.11	3	490	13	482	0.0e+00	534.9	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
2918244179	583	98.26	1	559	10	630	0.0e+00	447.6	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2918244180	82	78.85	1	82	23	104	9.6e-31	100.4	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
2918244181	315	98.41	3	315	4	313	1.1e-117	387.6	COG0275	16S rRNA C1402 N4-methylase RsmH	314
2918244182	134	86.99	1	134	18	144	3.0e-41	135.1	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
2918244184	291	99.26	10	288	2	271	4.3e-102	335.2	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
2918244185	604	98.02	1	599	9	601	0.0e+00	566.7	COG3107	Outer membrane lipoprotein LpoA, binds and activates PBP1a	604
2918244186	123	97.37	6	123	3	113	8.6e-40	129.7	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
2918244187	197	100	3	181	1	177	2.1e-77	253.2	COG0279	Phosphoheptose isomerase	176
2918244188	192	95.94	2	192	8	196	2.7e-51	168.9	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918244190	143	97.42	1	143	5	155	3.8e-56	183.8	COG2969	Stringent starvation protein B	155
2918244191	207	97.67	7	207	4	213	2.8e-43	142.7	COG0625	Glutathione S-transferase	211
2918244192	259	87	1	259	37	277	6.1e-63	207.5	COG2857	Cytochrome c1	250
2918244193	404	99.26	1	401	4	405	0.0e+00	548.4	COG1290	Cytochrome b subunit of the bc complex	381
2918244194	197	93.89	1	197	5	173	2.2e-51	168.7	COG0723	Rieske Fe-S protein	177
2918244195	130	95.49	1	130	7	133	4.9e-57	186.4	COG0103	Ribosomal protein S9	130
2918244196	142	96.62	1	142	1	143	4.4e-66	215.7	COG0102	Ribosomal protein L13	148
2918244197	346	99.69	1	346	1	319	4.0e-113	372	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918244198	332	97.85	4	332	5	322	9.3e-88	288.6	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918244199	339	90.32	1	338	36	371	0.0e+00	459.9	COG1485	Predicted ATPase	367
2918244200	449	50.85	352	396	4	33	8.4e-05	16	COG3422	Uncharacterized conserved protein YegP, UPF0339 family	59
2918244200	449	98.42	1	315	5	316	5.9e-88	289.3	COG0180	Tryptophanyl-tRNA synthetase	314
2918244201	211	95.24	3	211	5	204	3.4e-66	216.8	COG2945	Alpha/beta superfamily hydrolase	210
2918244202	145	95.65	1	144	3	134	6.1e-41	133.9	COG3105	Uncharacterized membrane-anchored protein YhcB, DUF1043 family	138
2918244203	396	98.24	4	396	5	394	0.0e+00	477.8	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2918244204	159	94.3	1	157	5	153	2.2e-39	129.5	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918244205	633	95.43	443	633	6	193	3.5e-58	190.2	COG0529	Adenylylsulfate kinase or related kinase	197
2918244205	633	95.62	19	459	2	416	0.0e+00	673.3	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
2918244206	305	93.28	1	305	19	268	3.9e-90	296.2	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2918244207	252	98.82	3	252	3	253	4.1e-77	253.2	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
2918244208	386	89.59	10	379	32	358	3.4e-114	376.1	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918244209	254	99.17	13	253	2	241	2.2e-116	381.5	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918244210	365	91.23	135	363	20	227	1.4e-66	218.5	COG0765	ABC-type amino acid transport system, permease component	222
2918244211	392	97.23	1	392	12	397	0.0e+00	574.4	COG4597	ABC-type amino acid transport system, permease component	397
2918244212	342	92.23	1	274	2	262	5.1e-45	148.5	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918244213	218	95.69	1	218	9	208	2.8e-43	142.3	COG0400	Predicted esterase	207
2918244214	463	73.46	50	462	29	410	0.0e+00	472.3	COG0513	Superfamily II DNA and RNA helicase	513
2918244216	148	96.64	1	147	5	148	3.2e-55	180.5	COG0314	Molybdopterin synthase catalytic subunit	149
2918244217	82	98.81	3	82	2	84	6.6e-21	69.3	COG1977	Molybdopterin converting factor, small subunit	84
2918244218	156	97.44	1	155	4	155	2.3e-68	223.3	COG0315	Molybdenum cofactor biosynthesis enzyme	157
2918244219	810	98.11	1	810	16	795	8.1e-55	181.3	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918244220	464	99.32	12	464	4	440	0.0e+00	562.2	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
2918244221	379	67.54	137	364	61	241	1.2e-09	32	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918244222	259	99.21	1	257	1	251	1.8e-107	353	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
2918244224	130	28.72	1	122	7	118	7.6e-13	42.8	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918244225	487	98.04	3	487	4	454	3.9e-50	164.9	COG1538	Outer membrane protein TolC	457
2918244226	392	99.8	25	392	2	510	2.7e-44	146.1	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918244227	221	88.94	4	221	18	218	3.7e-79	259.6	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918244228	257	25.88	165	252	163	221	1.7e-03	1.8	COG2977	4'-phosphopantetheinyl transferase EntD (siderophore biosynthesis)	228
2918244228	257	28.51	19	121	126	190	1.7e-03	8.8	COG2977	4'-phosphopantetheinyl transferase EntD (siderophore biosynthesis)	228
2918244230	438	98.09	1	425	1	410	1.7e-118	390.2	COG1004	UDP-glucose 6-dehydrogenase	414
2918244231	493	10.1	110	224	142	192	3.0e-25	19.7	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2918244231	493	40.2	213	470	299	501	3.0e-25	63.8	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2918244233	475	12.39	359	427	117	157	4.0e-14	16.5	COG0790	TPR repeat	292
2918244233	475	36.25	32	190	151	270	4.0e-14	13.4	COG0790	TPR repeat	292
2918244233	475	61.33	137	362	66	268	4.0e-14	24.9	COG0790	TPR repeat	292
2918244238	485	94.86	3	425	2	407	4.9e-127	418.5	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
2918244241	484	94.57	341	467	7	128	5.4e-42	136.3	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2918244241	484	99.7	1	332	2	335	0.0e+00	440.5	COG0836	Mannose-1-phosphate guanylyltransferase	333
2918244243	274	90.67	1	249	5	247	8.5e-52	170.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918244245	490	99.13	13	482	3	458	2.4e-114	377	COG1538	Outer membrane protein TolC	457
2918244246	353	94.32	1	353	13	344	3.7e-106	349.1	COG1566	Multidrug resistance efflux pump	352
2918244247	513	86.16	23	510	5	334	2.6e-20	60.2	COG0477	MFS family permease	338
2918244248	302	98.67	4	302	1	297	9.8e-38	125	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918244249	154	93.08	1	147	7	154	5.3e-18	60.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918244250	286	92.9	1	285	12	338	5.7e-89	291.3	COG1566	Multidrug resistance efflux pump	352
2918244252	725	98.98	21	719	3	681	6.4e-121	399	COG1289	Uncharacterized membrane protein YccC	674
2918244253	508	94.35	18	487	18	451	4.9e-103	339.7	COG1538	Outer membrane protein TolC	457
2918244254	315	98.01	2	300	2	296	3.9e-70	231.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918244255	324	99.69	1	319	1	326	6.1e-99	325.4	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918244256	300	95.35	1	293	10	296	2.6e-33	110	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918244257	291	78.79	169	291	22	125	5.1e-31	101	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918244258	795	94.84	20	790	17	770	5.7e-108	356.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918244259	327	93.19	1	324	8	308	5.6e-79	259.7	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918244260	184	90.32	3	178	12	179	2.6e-39	129.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918244262	524	20.09	376	499	344	432	4.8e-41	3.9	COG3182	Uncharacterized iron-regulated membrane protein	442
2918244262	524	87.13	1	378	1	386	4.8e-41	134.7	COG3182	Uncharacterized iron-regulated membrane protein	442
2918244263	101	21.79	13	84	31	81	5.8e-04	13.4	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
2918244264	164	87.63	1	164	12	174	3.3e-37	122.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918244265	309	95.98	2	307	12	321	1.3e-82	271.6	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918244266	775	97.35	76	775	21	754	0.0e+00	758.1	COG4772	Outer membrane receptor for Fe3+-dicitrate	753
2918244267	115	89.09	1	115	1	98	2.2e-06	22.5	COG1544	Ribosome-associated translation inhibitor RaiA	110
2918244270	156	95.65	2	141	5	136	2.2e-31	103	COG3223	Phosphate starvation-inducible membrane PsiE (function unknown)	138
2918244271	87	84.54	1	87	1	82	2.2e-29	96.1	COG3141	dsDNA-binding SOS-regulon protein, induction by DNA damage requires cAMP	97
2918244272	339	85.68	5	338	48	400	1.4e-73	241.8	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
2918244273	268	92.22	5	268	14	262	7.9e-47	154.2	COG2912	Regulator of sirC expression, contains transglutaminase-like and TPR domains	269
2918244274	209	98.14	1	209	1	211	7.1e-53	174.1	COG0625	Glutathione S-transferase	211
2918244275	430	99.27	41	430	2	272	1.8e-59	195.8	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918244276	433	99.06	4	433	4	426	0.0e+00	639.8	COG3508	Homogentisate 1,2-dioxygenase	427
2918244277	260	99.59	16	256	2	246	6.4e-62	203.1	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918244278	304	78.73	5	245	2	212	1.3e-52	173.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918244279	263	90.17	1	252	28	293	1.2e-30	101.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918244280	151	98.04	1	149	2	151	8.0e-26	85.7	COG0716	Flavodoxin	151
2918244282	190	94.36	1	185	7	190	1.3e-56	185.3	COG3224	Antibiotic biosynthesis monooxygenase (ABM) superfamily enzyme	195
2918244283	230	97.76	1	227	6	267	1.4e-29	97.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918244284	98	93.27	1	98	6	102	4.6e-52	169.1	COG3492	Uncharacterized protein	104
2918244286	302	97.15	4	288	8	280	1.5e-57	189.3	COG4757	Predicted alpha/beta hydrolase	281
2918244287	403	99.25	2	403	2	396	0.0e+00	663.8	COG3007	Trans-2-enoyl-CoA reductase	398
2918244288	178	95.31	2	177	2	184	3.4e-44	144.6	COG3658	Cytochrome b	192
2918244289	88	79.61	1	88	21	102	1.2e-23	77.8	COG5591	Uncharacterized protein	103
2918244290	392	99.75	1	392	1	393	0.0e+00	516.9	COG0183	Acetyl-CoA acetyltransferase	392
2918244291	239	94.78	1	238	8	261	8.7e-26	85.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918244292	769	91.24	9	349	15	316	0.0e+00	46.8	COG0620	Methionine synthase II (cobalamin-independent)	330
2918244292	769	99.4	435	766	2	330	0.0e+00	452.7	COG0620	Methionine synthase II (cobalamin-independent)	330
2918244293	517	83.96	1	274	6	251	2.1e-22	73.7	COG0685	5,10-methylenetetrahydrofolate reductase	291
2918244300	149	74.85	1	146	3	130	5.7e-09	29.7	COG3153	Predicted N-acetyltransferase YhbS	171
2918244303	138	83.59	1	127	1	107	3.1e-17	57.3	COG4969	Tfp pilus assembly protein, major pilin PilA	125
2918244304	402	99.25	5	402	3	397	6.8e-119	391.5	COG1459	Type II secretory pathway, component PulF	397
2918244305	288	94.92	13	286	5	247	7.3e-80	262.6	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
2918244306	207	97.01	7	205	3	197	2.0e-61	201.6	COG0237	Dephospho-CoA kinase	201
2918244307	66	86.15	1	66	2	57	5.3e-28	91.2	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
2918244308	226	99.1	1	226	2	222	9.0e-80	261.9	COG3235	Uncharacterized membrane protein	223
2918244311	431	98.78	1	420	2	406	0.0e+00	438.1	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2918244316	832	97.02	1	832	21	801	0.0e+00	1129.6	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918244317	245	98.41	5	243	3	249	1.9e-84	277.2	COG1496	Copper oxidase (laccase) domain	249
2918244318	320	98.63	6	302	4	291	9.4e-95	311.7	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2918244319	339	95.28	1	263	1	242	2.3e-88	290.1	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
2918244321	365	96.65	1	364	3	377	2.9e-76	251.6	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918244322	132	97.84	1	130	4	139	7.4e-24	79	COG4968	Tfp pilus assembly protein PilE	139
2918244323	160	12.24	84	144	157	180	1.4e-09	3.6	COG4726	Tfp pilus assembly protein PilX	196
2918244323	160	28.57	1	72	10	65	1.4e-09	29.8	COG4726	Tfp pilus assembly protein PilX	196
2918244325	111	37.58	1	83	12	73	4.1e-14	47.1	COG4967	Tfp pilus assembly protein PilV	162
2918244326	146	37.5	1	143	22	90	1.1e-08	26.7	COG4970	Tfp pilus assembly protein FimT	181
2918244327	315	96.95	1	296	2	287	6.6e-127	416.9	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
2918244328	145	79.1	4	144	2	141	5.2e-48	157.1	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
2918244329	171	92.81	5	171	9	163	3.4e-50	164.1	COG0597	Lipoprotein signal peptidase	167
2918244330	943	99.68	2	937	1	944	0.0e+00	1152.1	COG0060	Isoleucyl-tRNA synthetase	933
2918244331	316	99.02	1	307	1	304	2.2e-112	369.5	COG0196	FAD synthase	304
2918244332	512	99.03	1	510	5	517	0.0e+00	686.4	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
2918244334	92	97.73	1	88	2	87	2.1e-32	106	COG0268	Ribosomal protein S20	88
2918244335	766	42.68	511	755	41	276	0.0e+00	229.5	COG3008	Paraquat-inducible protein B	553
2918244335	766	43.04	278	517	45	282	0.0e+00	281.1	COG3008	Paraquat-inducible protein B	553
2918244335	766	50.45	2	288	11	289	0.0e+00	384.2	COG3008	Paraquat-inducible protein B	553
2918244336	207	47.13	2	207	218	414	5.9e-81	266.9	COG2995	Uncharacterized paraquat-inducible protein A	418
2918244337	219	45.93	3	217	217	408	2.1e-44	144.6	COG2995	Uncharacterized paraquat-inducible protein A	418
2918244341	497	99.37	4	484	2	477	0.0e+00	508.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918244342	448	97.09	8	448	9	442	0.0e+00	471	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918244343	305	97.34	14	305	1	293	4.1e-46	152.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918244344	220	89.95	13	214	5	192	2.0e-23	78.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918244345	194	95.54	1	194	6	198	4.8e-53	173.9	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
2918244346	228	77.61	1	221	3	210	1.9e-32	107.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918244347	451	97.64	3	447	5	418	2.4e-111	366.7	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918244348	315	91.62	1	315	7	323	6.5e-108	355.3	COG1816	Adenosine deaminase	345
2918244349	238	73.73	4	143	15	101	5.2e-09	30.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918244351	393	95.82	1	386	5	371	4.7e-31	99.8	COG0477	MFS family permease	338
2918244352	65	91.78	1	65	4	70	2.9e-15	51	COG2608	Copper chaperone CopZ	71
2918244354	799	8.89	5	74	5	69	0.0e+00	32.1	COG2217	Cation transport ATPase	713
2918244354	799	99.45	70	794	2	728	0.0e+00	875.8	COG2217	Cation transport ATPase	713
2918244355	134	97.73	1	120	1	129	6.8e-36	117.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918244356	647	83.29	160	647	71	424	1.7e-102	338.1	COG0840	Methyl-accepting chemotaxis protein	408
2918244357	262	68.94	132	262	33	123	5.9e-23	75.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918244358	425	99.49	4	425	2	393	4.0e-95	313.5	COG0183	Acetyl-CoA acetyltransferase	392
2918244359	450	98.13	209	447	3	265	9.6e-56	180.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918244360	283	65.41	147	278	17	120	2.3e-17	56.6	COG2030	Acyl dehydratase	159
2918244361	101	93.2	1	101	2	97	3.5e-14	47.3	COG1694	NTP pyrophosphatase, house-cleaning of non-canonical NTPs	102
2918244362	249	52.05	2	189	44	170	1.3e-19	64.8	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2918244365	648	9.56	550	647	498	551	3.9e-45	8.2	COG4655	Uncharacterized membrane protein	565
2918244365	648	63.72	3	385	6	365	3.9e-45	149.2	COG4655	Uncharacterized membrane protein	565
2918244366	876	82.99	515	876	61	387	1.7e-52	173.9	COG0642	Signal transduction histidine kinase	336
2918244367	146	40.82	6	127	17	96	5.3e-12	40.2	COG4961	Flp pilus assembly protein TadG	185
2918244368	156	67.86	1	153	9	122	1.1e-20	68.4	COG4960	Flp pilus assembly protein, protease CpaA	168
2918244369	258	96.68	8	249	2	205	7.7e-47	153.8	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918244371	225	74.62	1	221	13	206	7.4e-27	88.5	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918244372	296	73.52	24	295	77	312	9.3e-27	88.3	COG2064	Pilus assembly protein TadC	320
2918244373	293	73.14	5	293	82	307	1.2e-58	192.7	COG4965	Flp pilus assembly protein TadB	309
2918244374	417	95.86	38	398	12	358	0.0e+00	468	COG4962	Pilus assembly protein, ATPase of CpaF family	355
2918244375	396	96.68	9	396	8	385	1.3e-57	189.7	COG4963	Flp pilus assembly protein, ATPase CpaE	366
2918244376	414	11.07	4	98	39	92	6.1e-91	15.9	COG4964	Flp pilus assembly protein, secretin CpaC	455
2918244376	414	52.87	125	404	198	455	6.1e-91	281.9	COG4964	Flp pilus assembly protein, secretin CpaC	455
2918244377	309	82.97	1	290	5	233	2.2e-37	122.5	COG3745	Flp pilus assembly protein CpaB	276
2918244378	62	84.48	6	61	6	54	2.9e-13	43.8	COG3847	Flp pilus assembly protein, pilin Flp	58
2918244379	135	25.27	5	134	5	122	2.8e-28	93.2	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918244380	555	98.21	2	555	8	557	1.5e-74	246.1	COG2831	Hemolysin activation/secretion protein	554
2918244381	784	99.32	12	784	5	733	0.0e+00	870.6	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
2918244382	97	60.87	39	96	18	59	4.3e-03	12	COG1983	Phage shock protein PspC (stress-responsive transcriptional regulator)	70
2918244383	1631	97.18	16	1631	46	1632	0.0e+00	1471.2	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
2918244384	445	95.87	2	445	13	453	1.7e-89	294.7	COG0534	Na+-driven multidrug efflux pump	455
2918244385	637	97.7	1	637	14	650	0.0e+00	900.6	COG1166	Arginine decarboxylase (spermidine biosynthesis)	652
2918244386	123	93.33	16	123	6	103	6.5e-29	94.3	COG0023	Translation initiation factor 1 (eIF-1/SUI1)	104
2918244387	179	82.26	15	178	7	159	4.4e-16	53.1	COG1443	Isopentenyldiphosphate isomerase	185
2918244388	355	100	1	354	1	358	4.5e-105	346	COG5345	Uncharacterized protein	358
2918244389	453	94.94	12	453	21	433	3.1e-112	369.6	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918244390	653	89.41	189	653	46	425	1.0e-83	276.5	COG0840	Methyl-accepting chemotaxis protein	408
2918244391	591	27.17	1	171	1	166	0.0e+00	96.6	COG4232	Thiol:disulfide interchange protein	569
2918244391	591	67.76	155	587	196	609	0.0e+00	434.8	COG4232	Thiol:disulfide interchange protein	569
2918244392	150	97.26	2	148	2	143	6.4e-66	214.8	COG0757	3-dehydroquinate dehydratase	146
2918244393	151	97.96	6	151	2	145	7.5e-45	147.8	COG0511	Biotin carboxyl carrier protein	140
2918244394	451	99.11	4	451	3	448	0.0e+00	670.2	COG0439	Biotin carboxylase	449
2918244395	297	99.34	1	292	2	303	1.7e-95	314.5	COG2264	Ribosomal protein L11 methylase PrmA	300
2918244397	337	98.77	4	325	2	322	9.0e-111	364.6	COG0042	tRNA-dihydrouridine synthase	323
2918244398	92	91.84	1	92	8	97	9.6e-42	136	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
2918244399	535	99.81	9	535	2	515	0.0e+00	778	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
2918244400	430	99.53	1	427	1	427	0.0e+00	613.5	COG0151	Phosphoribosylamine-glycine ligase	428
2918244401	924	89.47	367	771	6	124	4.6e-54	79.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918244401	924	96.24	786	917	3	130	4.6e-54	96	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918244402	198	97.56	1	198	3	202	1.0e-56	186	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
2918244403	563	82.7	10	297	2	264	1.6e-60	199	COG2073	Cobalamin biosynthesis protein CbiG	298
2918244403	563	98	309	563	2	246	5.7e-100	327.3	COG1010	Precorrin-3B methylase	249
2918244404	243	99.15	4	243	2	234	7.2e-85	278.7	COG2243	Precorrin-2 methylase	234
2918244405	208	96.21	1	208	4	206	1.2e-77	254.7	COG2082	Precorrin isomerase	210
2918244406	438	86.58	3	435	31	475	2.6e-77	254.6	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2918244407	403	98.93	217	400	2	186	6.2e-66	215.6	COG2242	Precorrin-6B methylase 2	187
2918244407	403	99.05	4	209	1	208	2.2e-59	194.6	COG2241	Precorrin-6B methylase 1	210
2918244408	364	96.73	3	363	7	361	1.1e-114	377.4	COG1903	Cobalamin biosynthesis protein CbiD	367
2918244409	240	97.28	1	240	3	252	3.5e-69	227.5	COG2099	Precorrin-6x reductase	257
2918244410	145	99.29	1	145	1	140	1.2e-26	88.1	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
2918244411	283	97.01	1	283	6	297	7.7e-69	226.8	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918244413	160	90.26	1	160	12	150	1.1e-42	139.8	COG2847	Copper(I)-binding protein	151
2918244415	688	25.53	8	316	74	276	1.8e-48	45.1	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918244415	688	49.81	324	688	400	795	1.8e-48	120.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918244416	454	98.19	5	454	3	437	0.0e+00	494.4	COG3182	Uncharacterized iron-regulated membrane protein	442
2918244417	471	97.19	7	467	7	455	0.0e+00	637.8	COG1113	L-asparagine transporter and related permeases	462
2918244418	421	97.81	11	396	6	363	1.5e-75	248.9	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918244419	495	98.01	196	494	5	299	1.5e-99	327.5	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918244420	359	93.81	14	359	19	321	1.8e-94	310.9	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918244421	285	96.48	34	285	7	253	1.3e-123	405.7	COG4674	ABC-type uncharacterized transport system, ATPase component	249
2918244422	232	94.94	1	229	3	227	2.1e-91	299.6	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918244423	171	98.22	2	169	2	167	2.4e-66	217.2	COG1247	L-amino acid N-acyltransferase YncA	169
2918244424	253	97.67	1	251	2	253	3.3e-69	227.3	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
2918244425	353	98.51	14	353	5	334	3.2e-91	300.2	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918244426	364	95.99	1	337	14	324	9.1e-51	167.5	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2918244427	336	98.49	3	336	5	330	3.3e-82	270.8	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918244428	196	97.75	3	196	3	219	3.7e-31	101.5	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918244429	289	98.97	1	289	1	287	2.5e-113	372.4	COG1946	Acyl-CoA thioesterase	289
2918244430	189	95.72	1	186	7	185	6.3e-34	112.1	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918244431	321	87.61	17	318	7	310	4.6e-71	233.9	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2918244432	414	98.53	9	409	6	406	7.6e-121	398	COG2081	Predicted flavoprotein YhiN	408
2918244433	443	79.81	1	440	29	443	0.0e+00	476.3	COG0513	Superfamily II DNA and RNA helicase	513
2918244434	159	87.5	1	157	5	172	7.7e-33	108.7	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
2918244435	250	99.16	1	250	1	235	3.5e-53	175.4	COG3416	Uncharacterized protein	233
2918244437	361	92.22	79	357	19	255	1.9e-24	78.6	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918244438	201	69.29	2	196	18	193	1.0e-36	121.4	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2918244439	375	85.56	60	302	25	267	5.7e-18	59.2	COG2801	Transposase InsO and inactivated derivatives	232
2918244440	842	93.8	1	841	54	870	0.0e+00	752.3	COG1643	HrpA-like RNA helicase	845
2918244442	290	93.44	3	290	6	290	3.4e-94	309.8	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2918244445	158	94.94	1	154	3	152	9.7e-42	137.1	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918244447	209	69.51	8	208	61	231	2.1e-68	224.5	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2918244448	487	99.58	206	467	1	236	1.9e-64	211.2	COG0775	Nucleoside phosphorylase	234
2918244449	550	92.73	53	450	26	395	2.2e-73	240.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918244450	659	82.23	265	651	68	391	6.9e-51	168.6	COG0642	Signal transduction histidine kinase	336
2918244451	265	95.44	5	260	3	253	3.6e-71	233.7	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
2918244452	207	95.26	1	205	4	204	8.6e-62	202.3	COG0352	Thiamine monophosphate synthase	211
2918244453	427	98.38	1	427	5	429	0.0e+00	629	COG0001	Glutamate-1-semialdehyde aminotransferase	432
2918244454	185	32.02	11	172	115	220	6.5e-22	72.9	COG0790	TPR repeat	292
2918244455	108	98.17	1	108	1	107	1.7e-55	180.4	COG4517	Uncharacterized protein	109
2918244456	332	95.88	2	330	9	334	0.0e+00	453.4	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
2918244457	162	92.21	1	150	11	152	2.5e-53	174.2	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
2918244458	279	93.52	1	279	8	281	1.2e-129	426.1	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
2918244459	505	97.5	1	504	8	514	0.0e+00	492.6	COG0815	Apolipoprotein N-acyltransferase	518
2918244460	253	97.84	13	253	3	228	1.2e-38	127.4	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
2918244462	868	99.88	1	867	1	822	0.0e+00	1110.5	COG0495	Leucyl-tRNA synthetase	814
2918244463	201	96.13	1	179	6	179	1.9e-32	106.7	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
2918244464	345	98.5	3	339	3	331	2.7e-100	330.2	COG1466	DNA polymerase III, delta subunit	334
2918244465	54	66.67	1	54	11	54	7.1e-16	52.3	COG3036	Stalled ribosome alternative rescue factor ArfA	66
2918244466	438	90.2	7	366	29	341	1.6e-123	406.5	COG2951	Membrane-bound lytic murein transglycosylase B	343
2918244467	316	97.76	10	311	5	310	5.2e-76	250	COG1619	Muramoyltetrapeptide carboxypeptidase LdcA (peptidoglycan recycling)	313
2918244468	338	98.37	32	337	4	304	0.0e+00	463.5	COG0320	Lipoate synthase	306
2918244469	215	90.67	1	212	12	215	6.9e-80	262	COG0321	Lipoate-protein ligase B	221
2918244470	91	93.33	1	91	7	90	5.0e-23	75.8	COG2921	Putative lipoic acid-binding regulatory protein	90
2918244471	386	95.93	1	385	14	390	0.0e+00	456.1	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2918244472	333	85.08	7	264	7	217	1.4e-69	228.9	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
2918244473	336	89.91	1	335	30	341	1.3e-109	361	COG2951	Membrane-bound lytic murein transglycosylase B	343
2918244474	380	96.34	9	379	7	374	2.9e-123	405.6	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
2918244475	629	97.78	6	615	5	622	0.0e+00	561.6	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2918244476	155	99.36	1	155	2	156	5.1e-58	190.1	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
2918244477	142	94.78	8	122	3	111	2.0e-40	131.5	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
2918244478	219	97.99	7	217	4	198	1.9e-59	195.2	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
2918244479	423	99.04	5	419	4	416	0.0e+00	591.6	COG0014	Gamma-glutamyl phosphate reductase	417
2918244480	230	96	8	216	5	196	8.3e-51	166.4	COG2094	3-methyladenine DNA glycosylase Mpg	200
2918244481	438	87.98	3	208	13	195	4.1e-44	145.1	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2918244482	196	90.5	1	195	11	210	6.9e-48	157.9	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
2918244483	238	98.26	10	238	3	228	1.7e-77	254.2	COG1346	Putative effector of murein hydrolase	230
2918244484	120	90.62	1	120	7	122	1.4e-30	100	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
2918244485	151	86.16	3	150	17	153	1.7e-40	132.1	COG2030	Acyl dehydratase	159
2918244486	577	37.59	248	321	66	118	5.7e-41	16.5	COG4642	Uncharacterized conserved protein	139
2918244486	577	75.89	25	138	32	138	5.7e-41	52.2	COG4642	Uncharacterized conserved protein	139
2918244486	577	89.36	128	253	15	140	5.7e-41	74.9	COG4642	Uncharacterized conserved protein	139
2918244487	213	69.57	6	211	3	194	6.8e-30	98.5	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2918244488	95	88.75	1	87	5	75	9.2e-23	74.6	COG5645	Uncharacterized conserved protein YceK	80
2918244489	209	97.91	3	205	3	189	2.2e-77	253.4	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
2918244490	449	98.05	1	449	8	459	0.0e+00	493.5	COG0773	UDP-N-acetylmuramate-alanine ligase	459
2918244491	659	99.35	2	657	4	611	0.0e+00	745.1	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
2918244492	506	99.37	19	501	2	477	0.0e+00	588.5	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918244493	482	95.33	21	480	3	471	3.4e-68	224.7	COG0531	Amino acid transporter	466
2918244494	464	99.34	2	457	3	452	0.0e+00	773	COG4303	Ethanolamine ammonia-lyase, large subunit	453
2918244495	272	79.59	1	248	60	293	6.9e-100	328.4	COG4302	Ethanolamine ammonia-lyase, small subunit	294
2918244496	152	67.72	9	150	44	171	2.6e-14	47.9	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918244497	215	91.83	12	215	10	200	1.8e-60	198.3	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2918244498	271	98.5	1	269	2	263	1.5e-100	330.5	COG3228	Mlc titration factor MtfA, regulates ptsG expression	266
2918244499	175	99.42	1	175	1	171	3.3e-70	229.7	COG0221	Inorganic pyrophosphatase	171
2918244508	691	93.43	1	580	22	561	0.0e+00	554.2	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2918244509	296	96.98	35	296	2	258	3.0e-69	226.9	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
2918244511	216	97.04	7	209	3	199	8.2e-79	257.3	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
2918244512	104	14.95	2	83	4	67	7.0e-08	25.4	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
2918244513	80	91.36	1	79	6	79	1.6e-26	85.7	COG1722	Exonuclease VII small subunit	81
2918244514	295	97.87	1	295	8	328	2.2e-84	275.2	COG0142	Geranylgeranyl pyrophosphate synthase	322
2918244515	631	99.2	13	630	2	623	0.0e+00	903.7	COG1154	Deoxyxylulose-5-phosphate synthase	627
2918244516	625	99.67	1	623	1	611	0.0e+00	483	COG4206	Outer membrane cobalamin receptor protein	608
2918244517	270	81.79	14	265	53	317	3.4e-37	121.9	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2918244519	205	97.96	2	194	5	196	2.6e-78	255.8	COG0807	GTP cyclohydrolase II	193
2918244520	249	56.54	46	247	116	275	7.7e-08	24.9	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918244521	167	90.68	13	163	13	158	4.5e-54	176.5	COG1267	Phosphatidylglycerophosphatase A	160
2918244522	321	99.38	1	317	3	320	3.3e-100	328.7	COG0611	Thiamine monophosphate kinase	317
2918244523	166	94.77	15	160	8	152	2.3e-42	138	COG0781	Transcription termination factor NusB	151
2918244524	158	98.68	3	154	2	151	9.8e-64	207.4	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
2918244525	363	87.76	204	363	2	173	4.6e-33	107.7	COG0807	GTP cyclohydrolase II	193
2918244525	363	98.52	1	204	3	202	1.8e-86	282.1	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
2918244526	221	97.56	1	206	1	200	5.2e-76	247.8	COG0307	Riboflavin synthase alpha chain	204
2918244527	376	95.89	4	149	6	145	1.5e-63	205.9	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
2918244527	376	97.73	150	371	2	216	2.9e-56	183.3	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
2918244528	154	96.79	1	154	1	151	2.5e-68	222.6	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
2918244529	150	83.65	1	150	9	141	1.1e-19	64.2	COG3126	Uncharacterized lipoprotein YbaY	158
2918244530	219	42.01	128	218	17	108	1.5e-57	46.3	COG3897	Predicted nicotinamide N-methyase	218
2918244530	219	66.67	2	158	12	157	1.5e-57	147.2	COG3897	Predicted nicotinamide N-methyase	218
2918244531	290	92.46	1	290	24	305	5.4e-100	328.6	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2918244534	236	87.17	14	233	20	216	9.8e-60	195	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918244535	421	59.41	121	418	203	505	4.2e-24	79.5	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918244536	180	92.77	8	180	9	162	3.4e-51	167.3	COG3495	Uncharacterized protein	166
2918244537	227	97.71	1	227	6	218	9.7e-79	257.7	COG3047	Outer membrane protein W	213
2918244538	417	95.95	7	400	11	389	6.4e-34	110.5	COG2814	Predicted arabinose efflux permease, MFS family	394
2918244539	147	90.83	1	116	6	114	2.9e-28	91.4	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2918244540	310	96.57	1	309	3	312	5.4e-89	292.5	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918244541	294	98.94	3	291	1	279	6.2e-63	206	COG1091	dTDP-4-dehydrorhamnose reductase	281
2918244542	279	52.88	3	275	11	166	2.3e-12	39.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918244543	270	73.85	6	184	17	112	2.9e-05	18	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918244544	480	98.01	1	441	8	450	0.0e+00	533.2	COG1115	Na+/alanine symporter	452
2918244545	329	91.9	1	326	25	353	2.0e-72	237.5	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
2918244547	640	99.33	1	471	1	445	0.0e+00	451.1	COG3276	Selenocysteine-specific translation elongation factor	447
2918244548	475	94.43	71	469	13	385	0.0e+00	457.3	COG1921	Seryl-tRNA(Sec) selenium transferase	395
2918244549	306	98.38	2	306	4	306	9.7e-93	304.5	COG3058	Formate dehydrogenase maturation protein FdhE	308
2918244550	220	93.12	3	214	4	206	3.7e-75	245.7	COG2864	Cytochrome b subunit of formate dehydrogenase	218
2918244551	316	94.15	13	235	8	200	2.6e-61	200	COG0437	Fe-S-cluster-containing dehydrogenase component	203
2918244552	809	75.19	1	809	201	809	0.0e+00	471.6	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918244553	196	22.35	2	196	2	182	2.4e-47	155.3	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918244554	187	99.42	2	187	2	171	5.7e-53	173.3	COG0629	Single-stranded DNA-binding protein	167
2918244555	464	41.51	254	442	54	212	6.5e-34	26.9	COG0477	MFS family permease	338
2918244555	464	74.93	10	322	8	294	6.5e-34	84.3	COG0477	MFS family permease	338
2918244556	944	99.57	1	941	4	940	0.0e+00	1484.1	COG0178	Excinuclease UvrABC ATPase subunit	935
2918244557	154	98.09	1	154	1	154	1.4e-63	207.1	COG2193	Bacterioferritin (cytochrome b1)	157
2918244558	479	95.81	1	479	14	493	0.0e+00	738	COG0753	Catalase	496
2918244559	128	100	1	116	1	116	6.1e-54	174.8	COG0203	Ribosomal protein L17	116
2918244560	333	99.69	8	327	1	318	1.7e-123	405.4	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
2918244561	206	100	1	206	1	210	8.9e-66	215.2	COG0522	Ribosomal protein S4 or related protein	205
2918244562	129	100	1	129	1	130	1.9e-60	196.5	COG0100	Ribosomal protein S11	129
2918244563	118	96.69	1	118	1	117	1.5e-53	173.9	COG0099	Ribosomal protein S13	121
2918244565	38	100	1	38	1	38	9.8e-25	80.2	COG0257	Ribosomal protein L36	38
2918244566	429	95.23	1	418	18	436	0.0e+00	502.7	COG0201	Preprotein translocase subunit SecY	436
2918244567	144	98.05	1	144	1	151	8.3e-47	152.8	COG0200	Ribosomal protein L15	152
2918244568	58	98.18	4	58	1	54	2.0e-23	75.6	COG1841	Ribosomal protein L30/L7E	55
2918244569	166	88.04	1	166	20	181	1.3e-67	220.4	COG0098	Ribosomal protein S5	181
2918244570	116	96.03	1	116	6	126	4.9e-43	140.3	COG0256	Ribosomal protein L18	125
2918244571	177	98.88	1	177	1	177	5.8e-71	231.4	COG0097	Ribosomal protein L6P/L9E	178
2918244572	130	100	1	130	1	133	3.5e-51	166.2	COG0096	Ribosomal protein S8	132
2918244573	101	98.36	41	101	2	61	5.0e-26	84.4	COG0199	Ribosomal protein S14	61
2918244574	179	99.44	1	179	1	179	4.4e-80	261.2	COG0094	Ribosomal protein L5	180
2918244575	104	98.15	1	103	2	107	3.0e-30	98.4	COG0198	Ribosomal protein L24	104
2918244576	122	100	1	122	1	123	4.0e-59	191.7	COG0093	Ribosomal protein L14	122
2918244577	88	95.4	1	87	4	86	9.8e-41	131.4	COG0186	Ribosomal protein S17	87
2918244578	63	94.12	1	63	1	64	1.9e-26	85.6	COG0255	Ribosomal protein L29	69
2918244579	137	93.29	1	137	2	140	1.0e-57	187.7	COG0197	Ribosomal protein L16/L10AE	146
2918244580	228	91.42	12	228	1	213	1.5e-97	319.1	COG0092	Ribosomal protein S3	233
2918244581	110	91.28	1	110	10	145	1.8e-42	138.3	COG0091	Ribosomal protein L22	120
2918244582	91	97.85	1	91	2	92	4.8e-42	135.5	COG0185	Ribosomal protein S19	93
2918244583	274	99.64	1	274	1	274	5.2e-126	413.2	COG0090	Ribosomal protein L2	275
2918244584	99	95.74	6	98	2	91	6.0e-33	107	COG0089	Ribosomal protein L23	94
2918244585	200	94.01	1	200	9	212	1.4e-70	230.6	COG0088	Ribosomal protein L4	214
2918244586	211	96.92	2	211	2	221	3.0e-81	266.1	COG0087	Ribosomal protein L3	218
2918244587	103	98.08	1	103	1	102	1.1e-47	154.2	COG0051	Ribosomal protein S10	104
2918244588	397	99.75	1	397	2	394	0.0e+00	715.7	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2918244589	715	99.04	1	715	2	723	0.0e+00	941.5	COG0480	Translation elongation factor EF-G, a GTPase	697
2918244590	156	99.32	2	149	2	148	5.9e-65	211.1	COG0049	Ribosomal protein S7	148
2918244591	123	95.35	1	123	7	129	3.5e-62	201.4	COG0048	Ribosomal protein S12	129
2918244593	1399	3.7	889	1263	420	449	0.0e+00	12.1	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2918244593	1399	7.03	1299	1382	689	745	0.0e+00	17.8	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2918244593	1399	99.38	13	853	3	808	0.0e+00	988.8	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2918244594	1357	99.54	1	1357	3	1083	0.0e+00	1495.9	COG0085	DNA-directed RNA polymerase, beta subunit/140 kD subunit	1060
2918244596	121	100	1	121	1	125	6.6e-44	143.1	COG0222	Ribosomal protein L7/L12	124
2918244597	166	91.48	1	166	5	165	1.7e-53	174.5	COG0244	Ribosomal protein L10	175
2918244599	231	99.57	1	227	1	229	2.9e-90	295.5	COG0081	Ribosomal protein L1	228
2918244600	143	99.29	2	143	1	140	5.8e-64	208	COG0080	Ribosomal protein L11	141
2918244601	159	89.07	1	159	20	182	8.6e-59	192	COG0250	Transcription antitermination factor NusG	178
2918244602	122	94.52	47	119	4	72	4.5e-27	87.3	COG0690	Preprotein translocase subunit SecE	73
2918244604	397	100	1	397	1	394	0.0e+00	717.8	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2918244609	249	99.21	1	249	1	251	4.6e-52	170.6	COG1521	Pantothenate kinase type III	251
2918244610	319	87.34	1	74	8	76	5.0e-20	63.8	COG1654	Biotin operon repressor	79
2918244610	319	98.74	81	316	2	237	1.7e-68	224.3	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
