gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
641158817	1424	25	729	1098	108	460	2.0e-19	92.9	COG2319	WD40 repeat	466
641158817	1424	31.45	25	290	2	279	1.0e-42	169	COG0515	Serine/threonine protein kinase	384
641158820	206	35.96	3	200	2	203	8.0e-37	147	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
641158821	220	21.71	15	189	8	174	1.0e-05	43.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641158822	505	31.99	1	443	8	443	2.0e-76	280	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
641158823	279	38.57	1	210	1	205	1.0e-38	153	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
641158832	268	27.11	3	268	1	267	6.0e-31	128	COG1834	N-Dimethylarginine dimethylaminohydrolase	267
641158833	118	47.37	5	118	24	137	4.0e-36	143	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
641158838	292	31.78	11	260	3	249	1.0e-35	143	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641158845	602	21.56	51	600	15	597	1.0e-40	162	COG4264	Siderophore synthetase component	602
641158854	725	30.7	38	703	3	619	3.0e-95	343	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
641158857	259	30	1	238	1	243	4.0e-27	115	COG3332	Uncharacterized conserved protein, contains NRDE domain	270
641158859	465	37.47	45	436	2	387	1.0e-81	297	COG2262	50S ribosomal subunit-associated GTPase HflX	411
641158860	450	26.44	24	444	14	443	4.0e-41	162	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
641158862	311	36.46	1	94	9	104	7.0e-08	51.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
641158863	1251	53.74	332	1210	3	842	0.0e+00	1008	COG1410	Methionine synthase I, cobalamin-binding domain	842
641158863	1251	58.57	12	329	8	311	5.0e-111	396	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
641158864	288	31.03	18	274	40	308	7.0e-34	137	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641158866	821	21.13	84	808	10	765	9.0e-60	225	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
641158869	451	26.52	1	394	6	354	9.0e-42	165	COG0628	Predicted PurR-regulated permease PerM	355
641158873	771	23.32	178	753	23	509	9.0e-32	132	COG1657	Squalene cyclase	517
641158876	170	30.95	30	155	12	134	7.0e-23	99	COG0824	Acyl-CoA thioesterase FadM	137
641158878	319	43.36	12	293	5	282	6.0e-75	274	COG3220	Uncharacterized conserved protein, UPF0276 family	282
641158883	481	27.92	9	469	5	446	1.0e-49	191	COG0534	Na+-driven multidrug efflux pump	455
641158891	553	26.08	62	547	2	451	4.0e-64	239	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
641158892	442	22.67	16	433	11	449	3.0e-33	136	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
641158893	221	27.42	18	197	8	189	5.0e-17	81.3	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
641158894	184	25.71	10	176	2	164	1.0e-07	49.9	COG4539	Uncharacterized membrane protein YGL010W	180
641158896	143	47.58	19	142	12	135	6.0e-34	136	COG1607	Acyl-CoA hydrolase	157
641158897	356	34.97	35	356	29	348	2.0e-66	246	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
641158898	792	33.29	50	764	3	649	0.0e+00	496	COG0209	Ribonucleotide reductase alpha subunit	696
641158901	785	25.08	160	784	61	591	8.0e-45	175	COG3211	Secreted phosphatase, PhoX family	616
641158903	520	36.31	351	507	35	190	4.0e-29	123	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
641158907	269	24.14	35	263	42	266	5.0e-14	71.9	COG3752	Steroid 5-alpha reductase family enzyme	272
641158910	408	24.41	33	354	15	340	3.0e-16	80	COG1078	HD superfamily phosphohydrolase	421
641158911	348	22.92	116	347	82	316	6.0e-09	55.3	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
641158913	258	21.29	59	246	7	208	9.0e-10	57.6	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
641158914	304	30.98	4	293	2	292	2.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
641158918	419	28.57	27	332	1	305	1.0e-35	144	COG0515	Serine/threonine protein kinase	384
641158923	1013	26.72	41	452	5	447	3.0e-39	157	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
641158925	420	32.96	2	414	1	441	7.0e-75	274	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
641158930	989	23.41	63	389	2	285	1.0e-30	129	COG0515	Serine/threonine protein kinase	384
641158931	212	39.01	3	180	1	182	1.0e-22	99.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641158932	236	23.56	18	225	4	201	3.0e-09	55.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641158934	186	23.37	3	186	14	195	7.0e-06	43.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641158935	227	25.13	20	210	28	226	5.0e-12	64.7	COG0705	Membrane associated serine protease, rhomboid family	228
641158936	535	36.21	6	526	14	530	1.0e-104	374	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641158937	347	25.81	2	303	14	274	6.0e-20	91.8	COG0388	Predicted amidohydrolase	274
641158938	593	34.22	306	591	3	289	9.0e-49	188	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
641158943	399	22.01	12	350	1	335	2.0e-28	120	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
641158944	233	39.13	111	225	2	116	9.0e-14	70.4	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641158946	217	35.71	9	214	8	210	3.0e-31	128	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
641158947	117	35.71	1	98	2	97	1.0e-14	71.9	COG3536	Uncharacterized conserved protein, DUF971 family	120
641158948	315	35.41	1	302	2	292	2.0e-64	239	COG1131	ABC-type multidrug transport system, ATPase component	293
641158949	328	17.65	123	327	56	276	7.0e-09	55.1	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
641158955	832	41.88	41	811	5	750	0.0e+00	673	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
641158956	644	48.75	9	644	1	635	0.0e+00	767	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
641158965	545	25.66	5	516	32	547	1.0e-62	234	COG0747	ABC-type transport system, periplasmic component	556
641158966	325	39.38	1	325	2	316	2.0e-74	273	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
641158967	298	39.71	1	273	15	289	9.0e-53	200	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
641158968	339	50.16	5	319	1	316	2.0e-110	393	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
641158969	320	44.06	6	316	1	313	3.0e-89	322	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
641158972	452	20.95	84	452	13	359	9.0e-11	61.9	COG3405	Endo-1,4-beta-D-glucanase Y	360
641158974	606	39.68	479	604	2	127	1.0e-21	98.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641158975	219	45.1	9	212	8	211	7.0e-45	173	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
641158976	319	35.6	1	298	5	306	5.0e-47	181	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
641158978	1343	18.44	73	781	58	791	2.0e-33	139	COG3250	Beta-galactosidase/beta-glucuronidase	808
641158978	1343	46.79	870	1332	7	482	0.0e+00	507	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
641158979	235	32.63	3	235	1	230	3.0e-39	155	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
641158980	628	36.92	8	614	3	571	0.0e+00	515	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
641158981	542	41.1	37	524	1	442	2.0e-115	410	COG0166	Glucose-6-phosphate isomerase	446
641158987	383	29.73	78	359	50	337	9.0e-19	88.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
641158988	491	20.95	9	490	7	480	6.0e-13	69.4	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
641158991	269	21.61	5	269	27	288	2.0e-07	49.9	COG0382	4-hydroxybenzoate polyprenyltransferase	289
641158992	425	32.48	67	416	91	410	5.0e-51	195	COG2124	Cytochrome P450	411
641158993	601	25.54	358	586	12	225	2.0e-18	87.9	COG2114	Adenylate cyclase, class 3	227
641158996	138	31.25	7	131	1	117	5.0e-12	63.6	COG0517	CBS domain	117
641158997	140	31.62	14	130	1	115	5.0e-12	63.6	COG0517	CBS domain	117
641159005	168	30.77	35	167	40	177	2.0e-12	65.7	COG1525	Endonuclease YncB, thermonuclease family	192
641159007	455	25.88	53	219	49	184	5.0e-09	56	COG1525	Endonuclease YncB, thermonuclease family	192
641159011	376	21.47	1	366	1	366	6.0e-31	128	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
641159012	381	27.99	23	353	3	308	7.0e-30	125	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641159013	998	22.92	157	604	86	507	1.0e-14	76.2	COG3227	Zn-dependent metalloprotease	507
641159021	421	43.19	165	420	88	336	1.0e-56	214	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
641159024	591	43.71	1	500	1	451	3.0e-128	452	COG0541	Signal recognition particle GTPase	451
641159025	614	23.82	25	386	2	374	3.0e-27	116	COG0515	Serine/threonine protein kinase	384
641159032	778	25.94	1	315	5	315	6.0e-33	136	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
641159032	778	41.65	349	775	20	445	1.0e-106	381	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
641159033	738	53.7	50	736	3	680	0.0e+00	840	COG1770	Protease II	682
641159038	180	36.41	3	179	2	180	8.0e-29	120	COG1514	2'-5' RNA ligase	180
641159044	149	28.12	1	127	2	128	2.0e-19	88.4	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
641159056	725	27	460	659	35	225	1.0e-20	95.6	COG2114	Adenylate cyclase, class 3	227
641159057	960	24.14	33	378	2	290	1.0e-26	116	COG0515	Serine/threonine protein kinase	384
641159058	619	40.61	74	619	11	539	0.0e+00	520	COG0405	Gamma-glutamyltranspeptidase	539
641159060	302	28.79	34	289	19	279	3.0e-15	75.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641159061	446	28.67	8	444	1	406	4.0e-43	169	COG2124	Cytochrome P450	411
641159062	469	29.77	159	445	1	288	9.0e-33	134	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
641159067	581	33.33	4	571	1	549	7.0e-84	305	COG3044	Predicted ATPase of the ABC class	554
641159068	453	23.27	10	452	4	411	5.0e-32	132	COG2124	Cytochrome P450	411
641159072	719	29.18	220	587	6	362	7.0e-31	129	COG3852	Signal transduction histidine kinase, nitrogen specific	363
641159074	262	25.6	6	255	18	254	1.0e-23	103	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
641159080	471	36.76	53	439	6	367	7.0e-89	321	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
641159081	124	36.97	6	120	9	127	5.0e-19	86.5	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
641159082	375	43.67	105	262	1	156	4.0e-34	139	COG4335	3-methyladenine DNA glycosylase AlkC	167
641159084	133	29.06	18	132	18	128	7.0e-12	63	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
641159090	984	30.53	68	330	2	282	2.0e-37	151	COG0515	Serine/threonine protein kinase	384
641159092	214	30.68	16	188	2	177	8.0e-17	80.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641159098	564	21.32	6	553	7	575	1.0e-28	121	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
641159103	411	29.1	8	409	20	431	6.0e-56	211	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
641159104	415	26.73	9	399	7	402	3.0e-44	172	COG3464	Transposase	402
641159109	979	24.62	18	335	1	285	1.0e-31	132	COG0515	Serine/threonine protein kinase	384
641159112	266	33.92	9	227	3	227	4.0e-37	148	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
641159113	248	27.8	14	217	7	188	7.0e-13	67.9	COG0406	Broad specificity phosphatase PhoE	208
641159116	291	30.41	45	255	1	200	1.0e-24	107	COG0625	Glutathione S-transferase	211
641159120	209	28.64	4	204	2	200	5.0e-23	101	COG0625	Glutathione S-transferase	211
641159125	190	37.97	4	190	13	198	8.0e-36	143	COG4445	tRNA isopentenyl-2-thiomethyl-A-37 hydroxylase MiaE (synthesis of 2-methylthio-cis-ribozeatin)	203
641159128	102	34.85	4	65	5	68	4.0e-07	46.7	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
641159129	533	24.16	153	518	60	432	1.0e-19	91.6	COG5184	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	476
641159133	249	38.34	1	249	10	251	4.0e-50	191	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
641159134	255	37.29	6	237	63	288	2.0e-43	169	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
641159135	461	36.73	1	459	3	446	4.0e-98	351	COG0527	Aspartokinase	447
641159140	132	36.28	4	116	1	112	2.0e-13	68.5	COG1734	RNA polymerase-binding transcription factor DksA	120
641159142	252	41.83	2	251	12	245	7.0e-51	194	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
641159144	318	30.32	99	307	32	246	9.0e-16	77.8	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
641159151	215	33.66	1	205	23	174	5.0e-30	124	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
641159156	128	46.59	42	128	13	100	4.0e-09	53.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
641159157	280	45.97	33	280	8	255	1.0e-71	263	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
641159158	552	25.82	340	518	24	197	4.0e-15	76.8	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
641159158	552	26.13	36	331	7	279	2.0e-31	131	COG0515	Serine/threonine protein kinase	384
641159159	379	33.42	5	360	1	352	2.0e-48	186	COG2866	Murein tripeptide amidase MpaA	374
641159163	931	22.34	299	790	52	574	1.0e-11	66.1	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
641159165	193	42.01	18	186	20	182	9.0e-27	113	COG4341	Predicted HD phosphohydrolase	186
641159170	536	18.64	280	495	54	258	7.0e-06	45.9	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
641159171	201	20.9	4	194	1	201	1.0e-08	53.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641159174	151	56.67	1	150	12	160	6.0e-47	179	COG3236	Predicted NAD-dependent protein-ADP-ribosyltransferase YbiA, DUF1768 family	162
641159176	552	30.71	51	552	14	484	1.0e-82	301	COG2509	Uncharacterized FAD-dependent dehydrogenase	486
641159177	285	40.94	1	276	2	249	1.0e-65	243	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
641159178	970	25.23	36	356	2	285	5.0e-34	140	COG0515	Serine/threonine protein kinase	384
641159181	560	36.11	1	527	6	501	4.0e-73	269	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
641159182	225	33.49	4	197	1	200	1.0e-19	90.3	COG0625	Glutathione S-transferase	211
641159185	245	47.46	1	235	1	236	2.0e-72	265	COG4555	ABC-type Na+ transport system, ATPase component NatA	245
641159186	394	27.75	7	394	4	401	2.0e-25	110	COG1668	ABC-type Na+ efflux pump, permease component	407
641159188	745	25.21	383	737	10	356	4.0e-30	127	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641159188	745	28.87	53	316	2	278	2.0e-42	168	COG0515	Serine/threonine protein kinase	384
641159190	412	18.33	38	392	9	318	3.0e-11	63.6	COG3239	Fatty acid desaturase	343
641159191	226	25.33	1	225	9	234	3.0e-15	75.5	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
641159192	248	31.4	5	120	7	127	3.0e-13	69.2	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
641159193	509	36.86	263	509	72	289	3.0e-51	196	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
641159195	216	29.44	1	216	14	234	1.0e-24	106	COG0412	Dienelactone hydrolase	236
641159198	421	30.47	122	362	44	286	4.0e-25	109	COG4974	Site-specific recombinase XerD	300
641159204	130	40	14	68	6	60	2.0e-07	48.3	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
641159206	415	26.73	9	399	7	402	7.0e-44	171	COG3464	Transposase	402
641159211	411	29.85	80	396	15	333	8.0e-26	111	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
641159218	336	32.42	4	322	3	329	3.0e-43	169	COG5351	Uncharacterized protein	367
641159226	356	32.15	1	353	1	362	2.0e-66	246	COG5351	Uncharacterized protein	367
641159229	426	27.14	19	222	20	228	2.0e-14	74.2	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
641159231	238	29.95	10	213	34	234	1.0e-20	93.5	COG5031	Ubiquinone biosynthesis protein Coq4	235
641159235	211	20.9	1	201	2	200	7.0e-07	47.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641159236	452	22.52	18	449	31	459	6.0e-24	105	COG0277	FAD/FMN-containing dehydrogenase	459
641159239	141	32.87	1	139	1	141	9.0e-21	92.7	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
641159241	1053	28.76	13	1045	1	1008	0.0e+00	568	COG0841	Multidrug efflux pump subunit AcrB	1009
641159244	202	50.61	40	202	1	162	4.0e-56	210	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
641159245	252	27.32	69	247	4	175	2.0e-17	83.1	COG1913	Predicted Zn-dependent protease	181
641159247	431	45.59	1	429	2	447	2.0e-109	390	COG0527	Aspartokinase	447
641159251	469	28.98	14	464	8	451	6.0e-38	152	COG0531	Amino acid transporter	466
641159252	265	38.13	7	261	3	257	1.0e-50	193	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641159254	1066	25.39	24	321	2	289	8.0e-39	156	COG0515	Serine/threonine protein kinase	384
641159258	429	65.73	1	426	1	420	0.0e+00	619	COG0148	Enolase	423
641159259	428	45.68	2	316	9	332	4.0e-86	312	COG0460	Homoserine dehydrogenase	333
641159260	166	32.35	23	158	9	133	1.0e-21	95.7	COG0824	Acyl-CoA thioesterase FadM	137
641159261	334	51.67	13	328	2	327	2.0e-102	365	COG1494	Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase or related protein	332
641159265	234	32.54	42	210	4	167	1.0e-19	90.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641159266	562	19.18	16	552	8	449	6.0e-21	96	COG1538	Outer membrane protein TolC	457
641159268	283	33.49	55	262	64	271	9.0e-24	104	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
641159269	247	39.73	13	231	13	226	9.0e-46	177	COG3361	Uncharacterized protein YqjF, DUF2071 family	240
641159270	326	22.19	2	299	54	305	3.0e-17	83	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
641159273	340	25.56	36	295	11	266	3.0e-13	69.4	COG1575	1,4-dihydroxy-2-naphthoate octaprenyltransferase	303
641159274	496	27.33	39	473	5	403	3.0e-38	153	COG1228	Imidazolonepropionase or related amidohydrolase	406
641159275	432	26.12	33	409	7	398	2.0e-28	120	COG1228	Imidazolonepropionase or related amidohydrolase	406
641159277	345	24.37	88	344	28	293	2.0e-13	70	COG3386	Sugar lactone lactonase YvrE	307
641159280	581	31.49	22	310	2	302	3.0e-43	170	COG0515	Serine/threonine protein kinase	384
641159282	140	32.54	1	123	2	122	2.0e-17	81.6	COG3791	Uncharacterized conserved protein	133
641159283	826	60.36	2	772	6	773	0.0e+00	1083	COG0466	ATP-dependent Lon protease, bacterial type	782
641159285	226	35.61	3	206	2	200	9.0e-32	130	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
641159290	206	31.49	16	196	4	179	6.0e-19	87.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641159291	1014	22.53	74	529	14	425	8.0e-43	169	COG0612	Predicted Zn-dependent peptidase	438
641159292	238	33.2	1	238	5	236	5.0e-35	141	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
641159294	358	40.35	17	354	1	336	2.0e-65	242	COG1816	Adenosine deaminase	345
641159295	468	33.41	1	436	30	467	5.0e-73	268	COG1757	Na+/H+ antiporter NhaC	485
641159296	630	27.38	40	625	26	666	2.0e-72	267	COG1331	Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains	667
641159298	200	22.05	4	198	1	195	2.0e-09	56.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641159301	248	24.34	23	247	1	183	9.0e-21	94.1	COG0693	Putative intracellular protease/amidase	188
641159302	339	27	9	307	2	294	3.0e-21	96.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
641159304	410	26.22	165	389	3	201	3.0e-17	83.3	COG2114	Adenylate cyclase, class 3	227
641159305	413	21.68	9	368	3	303	2.0e-09	56.8	COG3547	Transposase	303
641159307	678	41.23	2	340	9	335	2.0e-70	260	COG4402	Uncharacterized protein	457
641159308	555	30.17	50	328	2	270	1.0e-34	141	COG0515	Serine/threonine protein kinase	384
641159309	713	33.01	48	322	2	281	5.0e-35	143	COG0515	Serine/threonine protein kinase	384
641159310	187	33.33	22	171	26	181	4.0e-15	74.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641159312	693	32.66	5	686	17	748	4.0e-98	352	COG1444	tRNA(Met) C34 N-acetyltransferase TmcA	758
641159313	1824	27.96	286	1022	2	745	2.0e-72	268	COG3899	Predicted ATPase	849
641159313	1824	29.5	2	260	8	284	2.0e-30	129	COG0515	Serine/threonine protein kinase	384
641159313	1824	31.82	1560	1819	88	336	2.0e-32	135	COG0642	Signal transduction histidine kinase	336
641159318	270	30.08	5	226	23	252	7.0e-16	78	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641159325	270	45.74	9	263	5	249	7.0e-59	220	COG1691	NCAIR mutase (PurE)-related protein	254
641159326	277	36.64	8	269	1	261	5.0e-61	227	COG1606	ATP-utilizing enzyme, PP-loop superfamily	269
641159327	405	41.62	1	374	15	372	2.0e-67	250	COG1641	Uncharacterized conserved protein, DUF111 family	387
641159328	221	30.09	1	216	5	203	2.0e-29	122	COG0560	Phosphoserine phosphatase	212
641159330	1598	26.67	1250	1442	43	230	2.0e-17	86.1	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
641159330	1598	31.11	576	1108	9	595	1.0e-92	335	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
641159331	353	25.42	6	345	2	312	1.0e-26	114	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641159332	321	29.55	16	321	7	295	1.0e-40	160	COG1597	Diacylglycerol kinase family enzyme	301
641159333	237	26.49	72	213	22	170	3.0e-17	82.3	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
641159340	267	29.69	7	260	1	240	5.0e-26	111	COG2186	DNA-binding transcriptional regulator, FadR family	241
641159343	381	24.69	39	349	18	313	2.0e-24	107	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
641159345	227	25.45	1	219	1	216	2.0e-19	89.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
641159347	186	27.13	41	165	4	127	3.0e-11	61.8	COG0526	Thiol-disulfide isomerase or thioredoxin	127
641159348	381	42.41	6	380	4	369	5.0e-92	331	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
641159349	554	26.87	43	457	28	419	8.0e-41	162	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
641159350	623	31.5	32	342	7	329	1.0e-41	165	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
641159352	174	49.12	1	171	3	171	7.0e-48	183	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
641159354	154	23.57	1	151	20	176	9.0e-07	46.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641159355	470	27.66	38	300	2	277	3.0e-33	136	COG0515	Serine/threonine protein kinase	384
641159360	456	25.8	16	341	22	356	2.0e-29	123	COG0515	Serine/threonine protein kinase	384
641159362	327	41.89	1	322	3	331	8.0e-75	274	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
641159363	975	56.11	19	975	6	933	0.0e+00	1281	COG0178	Excinuclease UvrABC ATPase subunit	935
641159365	213	24.64	6	201	2	203	2.0e-13	69.5	COG0625	Glutathione S-transferase	211
641159366	330	35.91	9	330	8	326	6.0e-60	224	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
641159369	200	31.32	22	197	1	182	4.0e-17	81.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641159371	198	36.84	1	190	23	212	5.0e-32	131	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
641159379	238	36.1	4	230	1	240	7.0e-33	133	COG3279	DNA-binding response regulator, LytR/AlgR family	244
641159383	680	27.84	407	673	10	252	3.0e-35	144	COG0543	NAD(P)H-flavin reductase	252
641159384	258	31.22	6	217	5	220	2.0e-36	146	COG1941	Coenzyme F420-reducing hydrogenase, gamma subunit	247
641159385	457	33.1	26	454	6	430	8.0e-72	264	COG3259	Coenzyme F420-reducing hydrogenase, alpha subunit	441
641159386	162	27.85	1	155	2	155	9.0e-12	63.4	COG0680	Ni,Fe-hydrogenase maturation factor	160
641159388	734	39.43	2	726	13	747	0.0e+00	616	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
641159389	85	42.17	1	82	1	80	7.0e-14	68.8	COG0298	Hydrogenase maturation factor	82
641159390	370	46.61	1	367	1	362	2.0e-118	419	COG0409	Hydrogenase maturation factor	364
641159391	337	42.65	9	337	3	339	3.0e-77	282	COG0309	Hydrogenase maturation factor	339
641159393	274	29.13	1	248	5	240	1.0e-27	117	COG0300	Short-chain dehydrogenase	265
641159395	307	27.27	1	292	6	297	4.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
641159397	268	51.13	5	268	2	266	2.0e-80	292	COG0289	Dihydrodipicolinate reductase	266
641159398	300	50.89	5	283	2	282	6.0e-85	307	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
641159400	358	40.45	19	327	8	304	3.0e-72	265	COG0196	FAD synthase	304
641159410	566	30.03	237	563	12	353	2.0e-37	150	COG3852	Signal transduction histidine kinase, nitrogen specific	363
641159411	382	43.72	1	382	20	397	2.0e-97	349	COG1459	Type II secretory pathway, component PulF	397
641159412	368	55.4	3	353	2	352	0.0e+00	473	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
641159414	584	21.85	1	400	10	421	2.0e-23	103	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
641159415	319	40.06	1	310	1	304	9.0e-72	263	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
641159426	305	44.92	34	289	20	264	1.0e-64	240	COG1526	Formate dehydrogenase assembly factor FdhD	266
641159431	453	32.61	102	453	2	355	7.0e-54	205	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
641159432	737	27.93	103	718	17	563	3.0e-64	240	COG2936	Predicted acyl esterase	563
641159433	371	23.99	8	346	19	339	2.0e-23	104	COG3177	Fic family protein	348
641159434	545	45.37	1	534	1	524	0.0e+00	487	COG0459	Chaperonin GroEL (HSP60 family)	524
641159435	96	64.58	1	96	1	96	6.0e-32	128	COG0234	Co-chaperonin GroES (HSP10)	96
641159437	493	47.63	60	368	31	346	2.0e-67	250	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
641159442	597	18.63	14	464	3	388	5.0e-20	93.3	COG0644	Dehydrogenase (flavoprotein)	396
641159443	220	31.46	7	183	15	187	8.0e-26	110	COG0518	GMP synthase - Glutamine amidotransferase domain	198
641159445	486	41.59	35	480	2	436	5.0e-130	458	COG0621	tRNA A37 methylthiotransferase MiaB	437
641159446	441	20.97	37	345	21	304	7.0e-12	65.5	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
641159448	229	23.04	9	183	4	189	1.0e-09	56.8	COG2129	Predicted phosphoesterase, related to the Icc protein	226
641159449	188	37.04	29	163	58	190	2.0e-25	108	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
641159453	338	38.6	10	338	3	326	8.0e-65	240	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
641159454	104	54.55	1	88	1	80	1.0e-20	91.6	COG3813	Uncharacterized protein	84
641159457	115	28.57	3	107	2	109	8.0e-06	42.2	COG3795	Uncharacterized conserved protein	123
641159458	410	39.55	9	408	11	408	1.0e-63	237	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
641159461	391	25.47	2	363	12	366	8.0e-21	95.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
641159462	1043	26.7	1	1024	2	1005	0.0e+00	522	COG0841	Multidrug efflux pump subunit AcrB	1009
641159470	203	40.5	4	203	13	199	1.0e-35	143	COG4445	tRNA isopentenyl-2-thiomethyl-A-37 hydroxylase MiaE (synthesis of 2-methylthio-cis-ribozeatin)	203
641159474	316	24.57	17	301	2	265	6.0e-17	81.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641159476	687	37.14	1	380	4	388	8.0e-48	185	COG0475	Kef-type K+ transport system, membrane component KefB	397
641159477	474	29.28	4	178	5	179	1.0e-14	74.7	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
641159478	589	37.86	2	589	18	608	0.0e+00	506	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
641159479	328	58.36	1	328	1	329	0.0e+00	476	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
641159484	429	32.61	39	304	53	328	2.0e-46	180	COG3344	Retron-type reverse transcriptase	328
641159487	454	27.25	14	443	16	438	2.0e-46	180	COG0534	Na+-driven multidrug efflux pump	455
641159489	512	44.83	1	487	13	482	2.0e-130	459	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
641159490	798	52.28	8	793	11	781	0.0e+00	923	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
641159491	168	27.54	8	165	2	167	1.0e-05	43.1	COG2203	GAF domain	175
641159497	164	27.12	20	135	1	117	2.0e-13	69.1	COG0824	Acyl-CoA thioesterase FadM	137
641159502	222	57.14	47	221	1	173	7.0e-71	260	COG0225	Peptide methionine sulfoxide reductase MsrA	174
641159503	234	38.28	21	226	4	207	3.0e-30	125	COG2085	Predicted dinucleotide-binding enzyme	211
641159504	297	35.06	25	290	4	245	5.0e-48	185	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
641159505	171	49.71	1	171	1	170	8.0e-43	166	COG4675	Microcystin-dependent protein  (function unknown)	170
641159506	165	48.8	2	165	8	170	1.0e-39	155	COG4675	Microcystin-dependent protein  (function unknown)	170
641159507	449	22.17	9	411	2	398	1.0e-28	121	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
641159508	287	29.09	19	218	23	231	2.0e-15	76.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641159511	297	33.33	177	293	1	117	2.0e-13	70	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641159513	561	25.51	79	457	24	391	1.0e-41	164	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641159516	136	27.56	9	127	7	132	3.0e-10	57.7	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
641159517	138	40.2	13	114	12	113	1.0e-11	62.3	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641159518	297	31.96	177	272	3	99	4.0e-08	52.7	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641159520	602	38.05	13	598	2	567	3.0e-129	455	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
641159521	989	28.05	66	348	2	285	1.0e-36	149	COG0515	Serine/threonine protein kinase	384
641159527	312	28.48	12	312	1	292	2.0e-23	103	COG0583	DNA-binding transcriptional regulator, LysR family	297
641159528	222	30.28	15	215	3	205	4.0e-17	81.9	COG2910	Putative NADH-flavin reductase	211
641159529	129	29.2	14	123	17	125	1.0e-05	42.6	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
641159531	309	44.25	19	304	11	293	2.0e-61	229	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
641159533	222	58.99	3	218	6	222	6.0e-78	283	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
641159534	231	56.68	1	217	1	217	1.0e-78	285	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
641159537	368	31.72	74	360	37	323	4.0e-36	145	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
641159538	511	30.2	6	495	65	537	1.0e-75	277	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
641159539	437	31.22	28	384	1	346	6.0e-48	185	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
641159548	1262	25.44	47	309	2	274	1.0e-33	139	COG0515	Serine/threonine protein kinase	384
641159549	1094	26.85	331	651	17	310	6.0e-26	113	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
641159552	364	40	7	352	5	316	7.0e-85	307	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
641159553	286	31.45	4	239	3	241	3.0e-28	119	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641159554	220	30.61	1	184	6	198	2.0e-22	99.6	COG0300	Short-chain dehydrogenase	265
641159555	445	24.83	7	444	47	411	5.0e-30	125	COG2124	Cytochrome P450	411
641159557	659	33.33	81	641	7	544	9.0e-99	355	COG3975	Predicted metalloprotease, contains C-terminal PDZ domain	558
641159564	485	49.48	4	478	2	477	0.0e+00	541	COG0469	Pyruvate kinase	477
641159567	399	23.14	8	388	28	406	2.0e-10	60.5	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
641159569	193	33.67	1	193	2	196	8.0e-11	60.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641159574	389	21.5	1	349	7	372	1.0e-25	111	COG0641	Sulfatase maturation enzyme AslB, radical SAM superfamily	378
641159579	700	24.67	272	625	68	428	8.0e-22	99.3	COG5184	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	476
641159581	360	39.48	2	347	1	317	1.0e-77	283	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
641159584	123	35.59	6	123	1	116	2.0e-26	110	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
641159586	490	29.95	31	472	20	449	4.0e-36	146	COG0531	Amino acid transporter	466
641159587	394	23.87	1	222	7	218	4.0e-24	106	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
641159590	1394	26.4	806	1239	60	441	1.0e-33	139	COG2319	WD40 repeat	466
641159593	291	28.21	15	288	10	276	1.0e-31	130	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
641159594	303	30.13	5	302	2	296	5.0e-32	132	COG0583	DNA-binding transcriptional regulator, LysR family	297
641159596	375	29.11	3	363	34	375	2.0e-19	90	COG1680	CubicO group peptidase, beta-lactamase class C family	390
641159597	241	45.64	1	240	8	238	1.0e-47	183	COG0284	Orotidine-5'-phosphate decarboxylase	240
641159600	205	43.45	19	162	8	147	8.0e-30	123	COG1981	Uncharacterized membrane protein	149
641159601	235	20.33	2	223	4	234	5.0e-06	45	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641159602	323	36.03	11	301	5	295	4.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
641159603	248	36.63	16	247	4	242	1.0e-43	169	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
641159607	194	33.33	29	188	16	180	5.0e-18	84.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641159610	344	48.04	4	332	1	314	1.0e-90	326	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
641159612	427	23.15	8	426	1	421	1.0e-36	148	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
641159615	177	32.58	1	174	4	181	8.0e-22	96.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641159618	283	31.84	27	270	22	254	2.0e-26	113	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641159619	1152	26.22	12	318	2	283	2.0e-31	131	COG0515	Serine/threonine protein kinase	384
641159620	685	30.82	22	293	1	284	6.0e-41	162	COG0515	Serine/threonine protein kinase	384
641159621	213	35.61	4	208	2	193	5.0e-41	161	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
641159623	691	39.49	64	691	12	588	0.0e+00	497	COG0514	Superfamily II DNA helicase RecQ	590
641159625	280	35.38	5	259	3	250	2.0e-34	139	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641159638	235	43.61	9	233	3	228	2.0e-55	209	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641159643	622	36.5	15	613	1	567	4.0e-102	365	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
641159644	665	32.91	26	657	3	567	4.0e-95	342	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
641159645	1920	24.03	297	1084	2	737	6.0e-59	224	COG3899	Predicted ATPase	849
641159645	1920	28.21	12	272	1	279	2.0e-35	146	COG0515	Serine/threonine protein kinase	384
641159646	262	27.89	1	236	7	245	7.0e-24	104	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
641159647	833	42.55	697	832	4	142	7.0e-35	143	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
641159650	757	24.58	17	360	23	346	1.0e-38	155	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
641159650	757	34.57	374	719	2	322	7.0e-71	262	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
641159653	365	62.17	42	305	22	279	7.0e-78	284	COG0468	RecA/RadA recombinase	279
641159656	119	18.27	8	111	15	118	6.0e-06	42.9	COG1917	Cupin domain protein related to quercetin dioxygenase	131
641159657	404	19.76	12	396	29	428	1.0e-07	51.4	COG2271	Sugar phosphate permease	448
641159669	579	22.29	120	428	30	327	1.0e-07	51.9	COG3299	Uncharacterized phage protein gp47/JayE	353
641159673	340	20.06	5	287	7	295	9.0e-08	51.5	COG4379	Mu-like prophage tail protein gpP	386
641159680	300	33.01	13	115	20	121	4.0e-17	82.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641159680	300	38.96	146	299	5	153	8.0e-35	141	COG3449	DNA gyrase inhibitor GyrI	154
641159682	327	36.22	12	318	6	305	1.0e-67	250	COG3491	Isopenicillin N synthase and related dioxygenases	322
641159684	622	34.26	61	618	22	588	8.0e-109	388	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
641159686	195	59.22	16	193	4	178	1.0e-61	229	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
641159687	224	38.31	1	200	1	201	1.0e-32	133	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
641159688	186	34.24	8	186	1	183	8.0e-24	103	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
641159690	212	59.05	3	212	6	214	3.0e-70	257	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
641159692	842	23.55	424	699	21	284	3.0e-26	114	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
641159692	842	39.27	1	295	2	303	2.0e-71	264	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
641159693	407	31.23	6	388	2	385	3.0e-48	186	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641159694	254	44.86	1	243	8	244	2.0e-61	229	COG3208	Surfactin synthase thioesterase subunit	244
641159696	4089	32.26	839	1843	5	992	0.0e+00	521	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
641159702	146	31.31	38	136	18	113	6.0e-15	73.5	COG3628	Phage baseplate assembly protein W	116
641159704	547	19.5	18	542	22	549	1.0e-15	78	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
641159710	541	24.46	232	541	84	387	1.0e-38	154	COG3497	Phage tail sheath protein FI	394
641159716	488	34.23	57	488	15	449	5.0e-55	209	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
641159720	360	22.76	19	287	24	303	8.0e-19	88.3	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
641159721	554	27.78	4	213	3	232	8.0e-16	78.9	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641159723	265	37.88	1	261	3	257	3.0e-43	168	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641159724	162	37.91	11	162	2	154	3.0e-30	124	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
641159725	317	27.53	20	263	1	226	9.0e-23	101	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641159726	301	36.54	186	288	18	121	3.0e-20	92.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641159734	179	34.09	12	179	4	179	5.0e-16	77.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641159737	194	32.64	4	193	21	203	3.0e-29	121	COG5514	Uncharacterized protein	203
641159738	379	24.93	36	366	25	365	2.0e-27	116	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
641159739	1031	25.96	2	292	6	290	2.0e-34	141	COG0515	Serine/threonine protein kinase	384
641159746	236	32.35	1	232	25	251	4.0e-26	111	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641159747	299	21.24	12	297	9	292	4.0e-14	72.3	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
641159748	452	39.1	9	437	1	432	2.0e-87	316	COG0001	Glutamate-1-semialdehyde aminotransferase	432
641159749	326	44.09	3	314	2	308	2.0e-86	313	COG3458	Cephalosporin-C deacetylase or related acetyl esterase	321
641159750	337	41.27	16	323	8	321	1.0e-70	260	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
641159751	226	45.61	1	225	1	226	2.0e-69	255	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
641159754	362	25.45	88	362	43	308	5.0e-23	102	COG0668	Small-conductance mechanosensitive channel	316
641159756	480	34.35	8	464	14	466	7.0e-67	248	COG1757	Na+/H+ antiporter NhaC	485
641159760	368	21.67	37	355	31	323	7.0e-19	88.6	COG3239	Fatty acid desaturase	343
641159764	626	30.79	97	432	30	366	4.0e-18	87.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
641159765	469	25.06	25	455	21	455	2.0e-17	84.4	COG1538	Outer membrane protein TolC	457
641159766	402	24.35	4	284	20	325	7.0e-24	105	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
641159771	454	35.98	2	368	6	368	5.0e-65	242	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
641159772	436	21.09	25	433	34	438	2.0e-07	50.6	COG2271	Sugar phosphate permease	448
641159775	502	18.65	97	460	8	349	1.0e-28	121	COG0641	Sulfatase maturation enzyme AslB, radical SAM superfamily	378
641159778	633	24.19	17	301	23	331	8.0e-23	102	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
641159783	311	23.58	1	288	17	334	8.0e-21	94.7	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
641159787	224	36.7	27	214	3	182	5.0e-21	94.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641159788	768	23.12	431	744	8	347	6.0e-26	113	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
641159789	664	22.56	29	299	25	319	2.0e-23	104	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
641159795	405	20.73	38	392	33	382	3.0e-14	73.3	COG2814	Predicted arabinose efflux permease, MFS family	394
641159801	306	22.39	18	280	42	286	3.0e-08	52.7	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
641159804	437	48.47	1	419	29	448	3.0e-115	408	COG0513	Superfamily II DNA and RNA helicase	513
641159807	245	31.75	22	210	15	194	5.0e-23	101	COG0518	GMP synthase - Glutamine amidotransferase domain	198
641159808	243	25.94	1	236	2	240	2.0e-36	146	COG1385	16S rRNA U1498 N3-methylase RsmE	246
641159809	557	39.51	33	555	8	531	5.0e-111	395	COG1574	Predicted amidohydrolase YtcJ	535
641159812	634	22.64	6	309	13	322	1.0e-18	88.8	COG4972	Tfp pilus assembly protein, ATPase PilM	354
641159813	477	17.94	50	365	2	285	3.0e-07	50.4	COG3156	Type II secretory pathway, component PulK	323
641159817	141	25.71	17	116	5	109	9.0e-07	46.2	COG2165	Type II secretory pathway, pseudopilin PulG	149
641159818	422	40.1	1	419	1	395	5.0e-96	344	COG1459	Type II secretory pathway, component PulF	397
641159819	649	47.18	125	647	7	500	0.0e+00	531	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
641159820	777	22.9	60	695	21	571	7.0e-54	206	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
641159822	475	48.72	3	462	1	464	0.0e+00	505	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641159827	824	22.15	43	809	40	761	5.0e-54	206	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
641159828	480	37.56	1	445	6	443	2.0e-97	349	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
641159829	270	30.37	1	265	26	295	3.0e-35	142	COG0668	Small-conductance mechanosensitive channel	316
641159836	1570	34.6	6	924	5	808	0.0e+00	682	COG1201	Lhr-like helicase	814
641159839	174	32	9	149	10	159	7.0e-12	63.8	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
641159840	660	39.48	44	654	3	576	0.0e+00	529	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
641159841	403	39.05	11	384	1	370	5.0e-93	334	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
641159844	416	25.97	7	415	1	379	6.0e-24	105	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
641159845	445	23.53	13	417	10	414	8.0e-15	75.5	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
641159846	247	47.03	8	187	40	224	4.0e-57	215	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
641159848	782	27.27	69	511	16	458	7.0e-41	162	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
641159848	782	33.92	556	779	28	245	3.0e-34	140	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
641159850	427	53.24	9	425	3	411	3.0e-101	362	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
641159851	116	41.38	1	116	1	116	4.0e-30	123	COG3795	Uncharacterized conserved protein	123
641159853	499	42.08	133	498	111	457	3.0e-83	302	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641159856	549	26.36	157	529	60	427	4.0e-25	109	COG5184	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	476
641159862	898	42.36	6	285	12	299	9.0e-73	268	COG0258	5'-3' exonuclease	310
641159862	898	43.64	297	898	2	593	0.0e+00	560	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
641159863	230	35.38	35	223	5	192	3.0e-28	118	COG0406	Broad specificity phosphatase PhoE	208
641159864	381	33.47	1	243	76	326	2.0e-40	160	COG3344	Retron-type reverse transcriptase	328
641159865	389	39.81	20	121	6	108	3.0e-17	83	COG0607	Rhodanese-related sulfurtransferase	110
641159865	389	54.37	125	372	3	254	3.0e-77	282	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
641159868	486	30.7	34	463	5	411	4.0e-63	236	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
641159875	205	45.12	42	205	7	170	3.0e-45	175	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
641159877	176	38.64	1	176	34	178	5.0e-30	123	COG0563	Adenylate kinase or related kinase	178
641159879	326	25.9	35	309	24	293	8.0e-19	88.1	COG4542	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic...	293
641159880	369	31.89	20	317	5	297	6.0e-48	184	COG0031	Cysteine synthase	300
641159881	1059	29.67	56	335	2	285	2.0e-38	154	COG0515	Serine/threonine protein kinase	384
641159882	208	36.67	8	182	2	181	2.0e-19	89	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641159883	572	37.67	1	429	10	403	3.0e-77	283	COG4402	Uncharacterized protein	457
641159884	558	36.15	5	465	4	427	2.0e-81	297	COG4402	Uncharacterized protein	457
641159886	192	32.64	1	190	1	181	7.0e-22	97.4	COG0431	NAD(P)H-dependent FMN reductase	184
641159889	162	23.31	1	159	1	154	1.0e-17	82.7	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
641159890	552	19.75	139	489	18	421	2.0e-15	77.6	COG3517	Predicted component of the type VI protein secretion system	495
641159891	1102	22.71	582	810	16	264	2.0e-12	68.6	COG3515	Predicted component of the type VI protein secretion system	346
641159892	490	50.1	1	489	4	492	0.0e+00	649	COG3517	Predicted component of the type VI protein secretion system	495
641159893	163	45.57	3	157	6	162	9.0e-40	156	COG3516	Predicted component of the type VI protein secretion system	169
641159897	483	38.61	24	481	20	475	3.0e-96	346	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
641159898	382	35.83	2	371	4	373	9.0e-76	277	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
641159905	348	30.8	76	324	6	264	1.0e-42	167	COG0863	DNA modification methylase	302
641159906	494	25.86	1	486	1	489	1.0e-48	187	COG0591	Na+/proline symporter	493
641159911	552	36.01	61	503	39	490	4.0e-95	342	COG3540	Phosphodiesterase/alkaline phosphatase D	522
641159913	932	27.71	51	336	2	282	1.0e-32	135	COG0515	Serine/threonine protein kinase	384
641159915	266	42.48	1	265	14	268	7.0e-54	203	COG3752	Steroid 5-alpha reductase family enzyme	272
641159916	341	31.66	80	271	11	201	6.0e-11	62.2	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
641159918	409	33.91	236	406	2	175	8.0e-22	98.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641159919	154	36.54	4	151	7	157	3.0e-27	114	COG2131	Deoxycytidylate deaminase	164
641159920	602	32.89	308	602	46	330	5.0e-35	143	COG0642	Signal transduction histidine kinase	336
641159921	243	40.59	1	238	5	229	3.0e-46	178	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641159924	543	36.85	10	543	3	521	3.0e-115	409	COG1384	Lysyl-tRNA synthetase, class I	521
641159925	426	38.15	32	424	1	392	7.0e-76	278	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
641159926	1909	23.84	7	266	1	279	3.0e-23	105	COG0515	Serine/threonine protein kinase	384
641159926	1909	25.46	299	1034	2	739	2.0e-56	216	COG3899	Predicted ATPase	849
641159928	261	41.82	2	111	13	115	7.0e-17	81.1	COG3502	Uncharacterized conserved protein, DUF952 family	115
641159934	275	38.73	4	271	3	271	8.0e-55	207	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
641159937	247	28.17	1	241	5	255	3.0e-27	115	COG0300	Short-chain dehydrogenase	265
641159944	130	31.93	1	118	1	116	4.0e-08	50.4	COG1734	RNA polymerase-binding transcription factor DksA	120
641159945	483	34.32	9	477	14	472	8.0e-90	324	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641159946	451	33.77	4	450	1	443	2.0e-85	310	COG0174	Glutamine synthetase	443
641159949	401	41.44	274	384	2	112	1.0e-13	71.6	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641159952	250	20.07	4	250	5	258	3.0e-11	62.7	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
641159955	370	36.27	272	370	10	110	2.0e-09	56.9	COG0607	Rhodanese-related sulfurtransferase	110
641159959	990	24.55	37	352	2	285	3.0e-31	131	COG0515	Serine/threonine protein kinase	384
641159961	299	29.1	8	297	1	295	2.0e-30	126	COG0583	DNA-binding transcriptional regulator, LysR family	297
641159962	334	34.71	1	323	1	326	6.0e-47	181	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
641159964	376	30.11	1	348	17	351	1.0e-66	247	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
641159966	356	29.22	1	193	13	230	2.0e-21	96.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641159966	356	40.82	258	352	12	107	1.0e-15	77.7	COG0607	Rhodanese-related sulfurtransferase	110
641159968	431	42.09	110	431	124	454	9.0e-83	301	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641159971	245	30.68	4	88	3	84	2.0e-07	49.9	COG1977	Molybdopterin converting factor, small subunit	84
641159971	245	39.13	109	245	4	141	2.0e-33	136	COG0314	Molybdopterin synthase catalytic subunit	149
641159973	283	34.15	46	283	1	237	5.0e-30	125	COG4798	Predicted methyltransferase	238
641159975	759	46.18	426	749	1	324	3.0e-89	323	COG0280	Phosphotransacetylase	327
641159975	759	57.35	1	417	13	420	0.0e+00	536	COG0281	Malic enzyme	432
641159977	548	23.32	337	542	3	220	6.0e-18	86.1	COG0569	Trk K+ transport system, NAD-binding component	225
641159985	343	40.99	7	343	1	342	2.0e-66	246	COG2008	Threonine aldolase	342
641159987	427	52.76	1	427	1	429	0.0e+00	524	COG0104	Adenylosuccinate synthase	430
641159988	442	35.29	24	361	5	332	3.0e-47	183	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
641159989	445	22.64	2	442	1	405	2.0e-32	134	COG4198	Uncharacterized conserved protein, DUF1015 family	405
641159990	423	46.98	1	423	1	423	4.0e-122	431	COG0151	Phosphoribosylamine-glycine ligase	428
641159991	543	52.9	13	543	1	515	0.0e+00	638	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
641159995	285	27.07	4	251	7	234	6.0e-08	51.9	COG3770	Murein endopeptidase	284
641159999	444	36.16	7	438	1	444	6.0e-100	357	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
641160000	498	39.54	21	489	1	470	3.0e-109	389	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641160001	500	45.36	19	491	23	484	7.0e-126	444	COG1953	Cytosine/uracil/thiamine/allantoin permease	497
641160002	490	34.55	6	444	4	424	3.0e-103	369	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
641160003	288	32.38	4	283	2	268	2.0e-47	182	COG0388	Predicted amidohydrolase	274
641160004	649	58.74	1	600	4	579	0.0e+00	659	COG0443	Molecular chaperone DnaK (HSP70)	579
641160005	794	52.55	8	790	2	782	0.0e+00	1008	COG0466	ATP-dependent Lon protease, bacterial type	782
641160010	284	39.33	2	266	5	257	2.0e-53	202	COG1192	Cellulose biosynthesis protein BcsQ	259
641160011	310	42.99	38	257	5	216	1.0e-30	127	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
641160014	290	57.89	7	290	1	279	7.0e-104	370	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
641160015	122	37.84	1	74	8	81	9.0e-11	58.9	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
641160017	263	18.83	13	163	33	185	7.0e-10	58	COG1716	Forkhead associated (FHA) domain, binds pSer, pThr, pTyr	191
641160019	431	46.18	184	431	90	337	4.0e-63	235	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
641160021	302	29.85	27	289	7	239	9.0e-36	144	COG0688	Phosphatidylserine decarboxylase	239
641160022	473	45.17	4	473	1	443	0.0e+00	485	COG0174	Glutamine synthetase	443
641160024	121	62.73	12	121	3	112	7.0e-30	122	COG0347	Nitrogen regulatory protein PII	112
641160025	334	38.11	18	315	2	304	9.0e-64	237	COG0167	Dihydroorotate dehydrogenase	310
641160026	279	31.14	11	279	9	252	4.0e-33	135	COG0543	NAD(P)H-flavin reductase	252
641160027	165	31.52	1	154	13	177	2.0e-15	75.4	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
641160028	264	48.68	24	209	5	185	2.0e-52	199	COG0218	GTP-binding protein EngB required for normal cell division	200
641160029	388	43.78	1	201	2	197	6.0e-50	192	COG0237	Dephospho-CoA kinase	201
641160030	381	34.46	8	381	7	382	6.0e-59	221	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
641160031	218	38.42	1	196	1	200	1.0e-35	143	COG0625	Glutathione S-transferase	211
641160034	609	46.39	1	593	4	573	0.0e+00	531	COG0443	Molecular chaperone DnaK (HSP70)	579
641160036	346	38.61	1	314	5	300	1.0e-67	250	COG4974	Site-specific recombinase XerD	300
641160037	307	40.34	4	298	3	286	2.0e-59	223	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
641160048	667	17.64	28	525	30	490	5.0e-08	53.5	COG3225	ABC-type uncharacterized transport system involved in gliding motility, auxiliary component	538
641160050	248	43.32	1	212	10	224	2.0e-60	225	COG1131	ABC-type multidrug transport system, ATPase component	293
641160056	437	29.53	47	410	28	399	7.0e-51	195	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
641160060	604	29.69	7	278	2	279	2.0e-39	157	COG0515	Serine/threonine protein kinase	384
641160063	265	33.08	6	265	3	260	1.0e-36	146	COG3694	ABC-type uncharacterized transport system, permease component	260
641160064	264	35.5	6	264	7	268	6.0e-37	148	COG4587	ABC-type uncharacterized transport system, permease component	268
641160065	339	45.34	7	328	3	324	8.0e-90	324	COG4586	ABC-type uncharacterized transport system, ATPase component	325
641160066	470	36.86	79	459	6	373	1.0e-65	244	COG0006	Xaa-Pro aminopeptidase	384
641160067	342	28.34	18	285	45	343	4.0e-37	148	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
641160068	576	41.37	122	566	17	451	2.0e-110	393	COG1115	Na+/alanine symporter	452
641160070	896	37.65	38	822	9	766	0.0e+00	596	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
641160075	198	35.09	1	171	21	180	9.0e-31	126	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641160081	82	47.69	1	65	1	65	8.0e-14	68.8	COG1551	sRNA-binding carbon storage regulator CsrA	73
641160082	785	27.15	10	781	44	765	3.0e-83	303	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
641160084	503	28.24	18	472	9	500	3.0e-38	153	COG2268	Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain	548
641160087	456	40.66	2	450	13	464	3.0e-99	355	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641160090	408	24.15	9	347	5	338	1.0e-33	137	COG0515	Serine/threonine protein kinase	384
641160093	292	20.82	3	289	1	256	3.0e-17	82.7	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
641160094	612	55.63	9	598	2	584	0.0e+00	795	COG0173	Aspartyl-tRNA synthetase	585
641160095	659	29.04	126	635	17	512	7.0e-62	232	COG0815	Apolipoprotein N-acyltransferase	518
641160097	331	29.39	1	278	14	288	2.0e-19	89.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
641160099	1891	23.58	300	1042	4	737	7.0e-53	204	COG3899	Predicted ATPase	849
641160099	1891	26.39	21	271	15	283	4.0e-19	92.1	COG0515	Serine/threonine protein kinase	384
641160099	1891	32.23	1594	1890	47	335	3.0e-38	155	COG0642	Signal transduction histidine kinase	336
641160101	156	33.59	21	147	22	147	9.0e-17	79.5	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
641160106	135	32.33	1	133	2	129	2.0e-16	78	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
641160108	957	29.04	41	322	2	279	2.0e-36	148	COG0515	Serine/threonine protein kinase	384
641160110	197	30.94	5	181	2	182	1.0e-18	86.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641160111	286	29.67	13	285	1	257	2.0e-41	162	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641160112	406	38.44	31	406	5	387	1.0e-59	223	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641160117	214	33.7	14	190	1	181	1.0e-18	86.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641160118	1022	30.34	93	362	2	279	1.0e-34	142	COG0515	Serine/threonine protein kinase	384
641160120	214	34.25	13	190	2	182	5.0e-14	71.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641160129	714	33.7	267	446	3	181	8.0e-23	102	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
641160129	714	46.88	458	713	2	250	9.0e-73	268	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
641160130	370	36.18	22	358	1	315	6.0e-55	208	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
641160132	465	28.64	23	463	6	411	5.0e-53	202	COG2124	Cytochrome P450	411
641160133	755	24.88	546	746	2	204	3.0e-19	91.3	COG0288	Carbonic anhydrase	207
641160133	755	28.57	15	519	20	516	8.0e-67	249	COG0659	Sulfate permease or related transporter, MFS superfamily	554
641160136	264	50.58	5	262	10	259	8.0e-64	237	COG0434	Predicted TIM-barrel enzyme	263
641160138	339	30.36	29	130	1	112	7.0e-10	58.3	COG1388	LysM repeat	124
641160142	207	28.49	21	187	39	210	4.0e-17	81.5	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
641160147	571	69.3	9	552	12	555	0.0e+00	878	COG2987	Urocanate hydratase	561
641160148	416	38.26	7	415	1	401	3.0e-72	266	COG1228	Imidazolonepropionase or related amidohydrolase	406
641160151	209	32.77	8	180	1	177	1.0e-15	76.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641160152	1141	27.48	44	326	2	285	2.0e-36	148	COG0515	Serine/threonine protein kinase	384
641160154	225	26.07	4	208	1	201	2.0e-11	62.6	COG2910	Putative NADH-flavin reductase	211
641160157	181	36.26	5	180	3	184	2.0e-26	111	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
641160160	118	36.52	2	116	11	125	3.0e-21	93.7	COG1725	DNA-binding transcriptional regulator YhcF, GntR family	125
641160161	288	33.33	28	287	12	248	1.0e-41	163	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
641160165	314	32.62	1	313	4	326	1.0e-60	227	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
641160166	173	25.89	1	173	4	200	2.0e-20	91.8	COG1335	Nicotinamidase-related amidase	205
641160167	321	32.2	195	312	8	125	1.0e-20	94.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641160168	204	30.58	3	199	2	189	3.0e-29	121	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
641160169	185	21.52	10	167	4	153	1.0e-06	46.4	COG1225	Peroxiredoxin	157
641160171	428	26.39	37	311	4	279	5.0e-34	139	COG0515	Serine/threonine protein kinase	384
641160177	287	40.17	49	273	28	254	2.0e-57	216	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
641160178	941	33.33	293	391	4	105	5.0e-15	77.3	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
641160178	941	35.04	399	937	2	531	1.0e-113	405	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
641160179	540	30.3	7	102	6	104	1.0e-07	51.9	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
641160180	1007	24.84	716	966	4	315	3.0e-11	64.6	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
641160182	447	19.48	13	338	14	341	7.0e-09	55.4	COG3950	Predicted ATP-binding protein involved in virulence	440
641160184	164	47.68	8	157	1	151	3.0e-34	137	COG0782	Transcription elongation factor, GreA/GreB family	151
641160186	716	24.88	317	710	66	432	5.0e-39	156	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
641160188	209	40.54	1	109	1	111	6.0e-20	90.8	COG1733	DNA-binding transcriptional regulator, HxlR family	120
641160189	569	27.69	109	423	6	328	8.0e-34	138	COG0642	Signal transduction histidine kinase	336
641160190	288	30.74	14	236	20	247	8.0e-19	87.8	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
641160191	268	32.08	23	266	19	282	2.0e-19	89.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641160192	225	27.1	13	219	34	241	4.0e-14	71.9	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
641160194	175	44.05	2	169	8	175	2.0e-40	158	COG3310	Uncharacterized protein	196
641160196	293	32.25	1	292	1	298	2.0e-40	159	COG3246	Uncharacterized conserved protein, DUF849 family	298
641160197	679	49.92	4	667	2	645	0.0e+00	681	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
641160198	280	32.33	11	275	4	257	2.0e-39	156	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641160199	387	40.36	1	383	3	391	1.0e-84	307	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641160200	546	42.07	12	546	1	526	0.0e+00	523	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
641160201	312	36.68	13	264	3	249	6.0e-36	144	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641160202	230	26.94	14	206	3	193	9.0e-12	63.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641160208	540	30.62	78	469	36	416	3.0e-62	233	COG1649	Uncharacterized lipoprotein YddW, UPF0748 family	418
641160210	678	30.6	89	437	2	360	2.0e-46	180	COG0515	Serine/threonine protein kinase	384
641160215	491	28.82	69	401	46	324	4.0e-37	149	COG1858	Cytochrome c peroxidase	364
641160218	325	34.62	79	325	6	256	2.0e-38	153	COG0584	Glycerophosphoryl diester phosphodiesterase	257
641160225	592	24.56	38	291	2	277	7.0e-25	109	COG0515	Serine/threonine protein kinase	384
641160227	981	19.82	165	586	93	516	2.0e-10	62.1	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
641160238	407	15.77	21	372	3	303	1.0e-07	51.3	COG3239	Fatty acid desaturase	343
641160239	341	28.32	9	339	1	311	2.0e-37	149	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641160240	586	30.02	10	518	10	484	2.0e-59	224	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641160241	322	23.79	14	298	1	280	2.0e-18	86.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641160242	348	25.72	3	348	1	322	4.0e-45	175	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
641160244	416	24.92	58	330	22	300	5.0e-13	69.3	COG4188	Predicted dienelactone hydrolase	365
641160246	478	27.95	8	367	32	391	4.0e-34	139	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641160247	305	27.78	1	281	1	256	3.0e-33	135	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641160248	486	30.93	16	206	32	211	1.0e-16	81.5	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
641160249	803	49.49	4	777	5	778	0.0e+00	916	COG0466	ATP-dependent Lon protease, bacterial type	782
641160258	225	30.97	1	224	1	223	1.0e-32	133	COG0569	Trk K+ transport system, NAD-binding component	225
641160260	512	29.71	6	510	1	486	4.0e-62	232	COG0168	Trk-type K+ transport system, membrane component	499
641160262	250	31.45	120	242	3	125	3.0e-18	85.7	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
641160263	344	45.93	1	344	1	322	1.0e-93	336	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
641160267	684	43.03	13	348	22	352	5.0e-72	265	COG4402	Uncharacterized protein	457
641160269	298	31.25	26	296	14	269	9.0e-35	140	COG3752	Steroid 5-alpha reductase family enzyme	272
641160270	303	23.26	1	297	1	293	1.0e-19	90.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
641160274	339	33.61	213	328	1	119	4.0e-12	66	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641160280	416	35.42	7	415	3	381	6.0e-69	254	COG3268	Uncharacterized conserved protein, related to short-chain dehydrogenases	382
641160281	400	36.34	13	399	81	456	2.0e-75	276	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
641160283	128	34.92	7	127	1	126	1.0e-26	112	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
641160288	174	25.14	4	165	40	208	5.0e-08	51	COG0125	Thymidylate kinase	208
641160292	370	20.67	108	369	28	310	6.0e-12	65.6	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641160293	976	20.36	25	412	3	294	8.0e-10	59.9	COG1482	Mannose-6-phosphate isomerase, class I	312
641160297	205	35.03	29	184	20	173	2.0e-14	72.5	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
641160299	404	31.39	6	395	32	436	2.0e-44	173	COG2907	Predicted NAD/FAD-binding protein	447
641160300	1769	25.34	1476	1766	69	329	3.0e-23	105	COG0642	Signal transduction histidine kinase	336
641160300	1769	31.6	5	273	1	285	2.0e-34	142	COG0515	Serine/threonine protein kinase	384
641160300	1769	35.12	298	1148	2	849	0.0e+00	498	COG3899	Predicted ATPase	849
641160304	678	31.67	10	270	2	277	1.0e-42	168	COG0515	Serine/threonine protein kinase	384
641160306	686	26.23	459	686	31	274	3.0e-18	87.4	COG0790	TPR repeat	292
641160309	436	38.96	19	421	17	406	2.0e-71	262	COG0659	Sulfate permease or related transporter, MFS superfamily	554
641160311	363	26.96	18	302	2	272	2.0e-08	53.8	COG5464	Predicted transposase YdaD	289
641160316	255	46.58	70	229	2	156	8.0e-43	167	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
641160317	784	34.72	35	772	2	731	6.0e-120	425	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
641160318	355	32.58	1	352	1	283	2.0e-36	146	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
641160320	301	22.76	22	266	16	281	7.0e-09	55.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641160322	837	34.65	228	828	3	602	4.0e-129	456	COG4264	Siderophore synthetase component	602
641160324	615	34.32	10	608	4	602	6.0e-124	438	COG4264	Siderophore synthetase component	602
641160326	417	19.9	13	405	16	394	1.0e-05	44.8	COG2814	Predicted arabinose efflux permease, MFS family	394
641160327	466	41.12	16	442	3	428	3.0e-116	412	COG3486	Lysine/ornithine N-monooxygenase	436
641160328	556	32.33	95	556	26	458	5.0e-66	245	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
641160330	533	24.77	9	430	2	425	6.0e-18	85.8	COG3182	Uncharacterized iron-regulated membrane protein	442
641160334	602	36.77	5	602	13	608	0.0e+00	495	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
641160339	860	23.1	105	479	1	419	2.0e-22	101	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
641160342	182	32.17	49	182	40	177	3.0e-14	71.4	COG1525	Endonuclease YncB, thermonuclease family	192
641160346	207	42.51	2	207	1	201	7.0e-50	190	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
641160347	312	38.72	15	308	34	322	3.0e-61	229	COG0598	Mg2+ and Co2+ transporter CorA	322
641160349	158	34.93	14	156	44	187	6.0e-19	86.8	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
641160351	308	36.33	33	295	34	295	3.0e-47	182	COG1597	Diacylglycerol kinase family enzyme	301
641160355	471	49.89	1	454	3	457	0.0e+00	464	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641160356	325	44.1	1	321	8	318	6.0e-43	168	COG0530	Ca2+/Na+ antiporter	320
641160357	300	31.4	17	296	36	325	1.0e-39	157	COG3608	Predicted deacylase	331
641160358	300	31.21	1	292	5	317	2.0e-56	212	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
641160363	284	25.48	1	253	13	265	2.0e-17	83	COG0382	4-hydroxybenzoate polyprenyltransferase	289
641160364	404	20.27	5	275	27	289	2.0e-07	50.7	COG2988	Succinylglutamate desuccinylase	324
641160365	639	37.7	507	625	1	117	2.0e-16	81.3	COG0517	CBS domain	117
641160366	150	56.64	1	142	1	143	4.0e-49	186	COG1490	D-Tyr-tRNAtyr deacylase	145
641160368	265	23.66	34	261	69	313	2.0e-10	60.2	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641160369	107	42.42	8	105	5	103	2.0e-23	100	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
641160372	755	40.87	68	748	2	648	0.0e+00	599	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
641160373	331	22.66	1	331	8	288	1.0e-27	117	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
641160376	355	34.54	10	350	10	357	3.0e-59	222	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
641160377	320	36.45	9	302	3	296	2.0e-49	190	COG1577	Mevalonate kinase	307
641160378	344	36.34	7	327	6	310	6.0e-59	221	COG3407	Mevalonate pyrophosphate decarboxylase	329
641160379	810	27.46	45	364	1	302	3.0e-28	121	COG1577	Mevalonate kinase	307
641160379	810	33.1	386	806	23	435	6.0e-85	309	COG1257	Hydroxymethylglutaryl-CoA reductase	436
641160380	311	34.06	26	298	7	282	3.0e-46	179	COG1562	Phytoene/squalene synthetase	288
641160381	319	34.89	18	294	7	279	3.0e-41	162	COG1562	Phytoene/squalene synthetase	288
641160384	460	30.28	32	169	22	160	1.0e-08	54.7	COG3666	Transposase	161
641160387	438	24.34	1	431	17	456	1.0e-27	118	COG3349	Uncharacterized conserved protein, contains NAD-binding domain and a Fe-S cluster	485
641160388	340	38.89	47	207	48	204	7.0e-33	134	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
641160391	330	24.64	17	290	18	276	2.0e-27	116	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
641160394	550	41.18	7	74	14	79	2.0e-11	65	COG3831	WGR domain, predicted DNA-binding domain in MolR	85
641160395	522	24.63	118	513	2	399	8.0e-31	128	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
641160396	855	23.97	170	627	137	543	3.0e-36	147	COG4232	Thiol:disulfide interchange protein	569
641160406	268	32.63	13	202	8	193	4.0e-26	111	COG1381	Recombinational DNA repair protein (RecF pathway)	251
641160407	451	40.05	9	450	12	450	2.0e-95	343	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
641160414	635	29.4	24	596	4	524	4.0e-74	272	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641160416	343	26.77	48	298	38	286	4.0e-23	102	COG0668	Small-conductance mechanosensitive channel	316
641160424	238	27.5	159	237	2	78	2.0e-07	49.6	COG0695	Glutaredoxin	80
641160425	488	32.19	57	484	40	454	3.0e-56	213	COG5361	Uncharacterized conserved protein	458
641160426	323	31.15	203	323	3	124	3.0e-14	73	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641160427	1303	27.45	74	361	1	305	4.0e-34	141	COG0515	Serine/threonine protein kinase	384
641160433	240	40.54	2	222	25	241	3.0e-53	202	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
641160434	513	49.78	9	458	1	428	0.0e+00	511	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
641160437	402	42.74	31	400	2	357	4.0e-102	365	COG0787	Alanine racemase	360
641160439	228	32.08	6	217	1	210	7.0e-26	110	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
641160440	67	49.23	3	67	4	68	1.0e-13	68.3	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
641160441	263	60.39	11	263	6	260	4.0e-99	354	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
641160442	240	27.31	5	234	4	211	3.0e-13	69.2	COG0352	Thiamine monophosphate synthase	211
641160449	401	27.03	12	192	35	218	2.0e-20	93.8	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
641160450	296	26.02	29	293	16	280	1.0e-17	84	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641160452	126	44.35	6	126	1	120	1.0e-16	78.9	COG1734	RNA polymerase-binding transcription factor DksA	120
641160453	333	27.8	1	231	11	242	1.0e-26	113	COG0682	Prolipoprotein diacylglyceryltransferase	287
641160459	517	26.67	9	184	7	174	3.0e-08	53.8	COG2229	Signal recognition particle receptor subunit beta, a GTPase	187
641160462	303	45.38	55	303	6	250	2.0e-76	278	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
641160463	273	34.85	10	273	2	265	1.0e-50	193	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
641160465	327	29.55	17	256	43	270	9.0e-26	111	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
641160470	417	49.62	27	416	10	390	4.0e-124	438	COG0126	3-phosphoglycerate kinase	395
641160471	264	44.83	3	263	2	251	2.0e-62	232	COG0149	Triosephosphate isomerase	251
641160472	226	35.63	1	87	1	86	2.0e-13	69.1	COG1314	Preprotein translocase subunit SecG	86
641160474	286	37.89	10	282	1	268	3.0e-55	208	COG0253	Diaminopimelate epimerase	272
641160477	361	59.29	29	340	19	330	4.0e-122	431	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
641160485	365	24.18	93	310	88	310	1.0e-15	77.5	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641160486	187	23.53	2	169	13	198	2.0e-09	56.1	COG1011	FMN phosphatase YigB, HAD superfamily	229
641160492	561	31.16	10	219	4	212	3.0e-32	133	COG1131	ABC-type multidrug transport system, ATPase component	293
641160493	485	27.41	26	471	6	431	5.0e-49	188	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
641160497	556	31.65	7	243	1	214	1.0e-18	88.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641160499	190	28.99	13	177	14	182	6.0e-14	70.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641160505	292	40.91	8	291	2	285	2.0e-48	186	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
641160506	304	33.89	3	296	2	287	4.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
641160508	203	29.51	7	186	5	162	4.0e-15	74.6	COG0262	Dihydrofolate reductase	167
641160509	416	30.96	115	392	1	255	2.0e-41	163	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
641160511	329	22.81	6	287	2	264	2.0e-06	47.2	COG5464	Predicted transposase YdaD	289
641160512	327	50.62	4	325	1	321	6.0e-93	334	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
641160513	745	58.83	24	568	10	546	0.0e+00	684	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
641160513	745	61.83	605	735	9	139	1.0e-41	165	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
641160514	596	27.35	4	454	77	532	1.0e-53	204	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
641160515	261	53.73	1	253	1	255	7.0e-81	293	COG0024	Methionine aminopeptidase	255
641160518	421	33.64	1	421	1	410	6.0e-70	258	COG2124	Cytochrome P450	411
641160519	193	25.81	10	192	11	195	5.0e-08	51.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641160520	1037	28.2	19	1030	11	1006	0.0e+00	494	COG0841	Multidrug efflux pump subunit AcrB	1009
641160521	385	26.41	1	384	4	372	6.0e-16	78.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
641160522	450	45.6	23	450	11	436	0.0e+00	469	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
641160524	277	31.54	20	274	5	259	4.0e-36	145	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
641160525	341	25	1	298	2	290	1.0e-25	110	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
641160527	417	29.77	23	405	20	370	3.0e-34	139	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
641160528	451	27.8	36	440	13	404	4.0e-36	146	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
641160530	417	32.86	1	417	2	374	1.0e-73	270	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
641160531	324	32.11	1	317	1	311	3.0e-43	168	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641160532	353	26.91	25	346	23	334	3.0e-38	152	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
641160534	395	20.92	48	381	17	334	3.0e-14	73.4	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
641160536	630	51.03	2	630	10	597	0.0e+00	720	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
641160537	658	43.63	78	633	1	525	0.0e+00	602	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
641160538	410	34.42	18	410	28	410	2.0e-69	256	COG2124	Cytochrome P450	411
641160539	385	35.36	127	383	2	277	9.0e-47	181	COG0515	Serine/threonine protein kinase	384
641160540	287	26.42	43	287	26	241	9.0e-09	54.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641160542	234	24.86	21	193	26	197	3.0e-12	65.4	COG4912	3-methyladenine DNA glycosylase AlkD	222
641160543	319	33.22	25	316	42	319	3.0e-37	149	COG0385	Predicted Na+-dependent transporter	319
641160544	218	38.76	1	178	2	165	3.0e-28	118	COG0406	Broad specificity phosphatase PhoE	208
641160551	433	29.93	10	433	3	403	7.0e-60	224	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
641160554	105	64.36	5	105	3	103	3.0e-33	133	COG0261	Ribosomal protein L21	103
641160562	198	25.89	2	198	22	216	1.0e-14	73.1	COG0811	Biopolymer transport protein ExbB/TolQ	216
641160569	539	41.35	1	530	1	497	4.0e-117	415	COG0443	Molecular chaperone DnaK (HSP70)	579
641160570	205	52.5	5	204	1	195	2.0e-68	251	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
641160573	393	34.77	17	386	1	342	3.0e-72	266	COG1559	Cell division protein YceG, involved in septum cleavage	342
641160574	156	50.35	1	142	2	139	9.0e-34	136	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
641160583	222	24.66	84	214	16	161	7.0e-09	54.3	COG2453	Protein-tyrosine phosphatase	180
641160587	472	23.88	36	441	3	387	2.0e-38	153	COG0247	Fe-S oxidoreductase	388
641160588	139	47.41	5	139	1	130	6.0e-35	139	COG1592	Rubrerythrin	166
641160589	163	42.04	7	163	3	157	1.0e-42	165	COG1225	Peroxiredoxin	157
641160594	246	29.46	137	244	21	132	1.0e-09	57.3	COG3824	Predicted Zn-dependent protease, minimal metalloprotease (MMP)-like domain	136
641160595	379	24.56	101	371	42	312	8.0e-25	108	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
641160596	600	40.25	1	556	3	558	0.0e+00	586	COG0143	Methionyl-tRNA synthetase	558
641160599	93	46.84	12	88	1	79	3.0e-19	86.9	COG0695	Glutaredoxin	80
641160600	1385	37.5	821	1384	226	864	1.0e-81	299	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
641160603	183	37.23	17	110	1	94	3.0e-18	84.9	COG0360	Ribosomal protein S6	112
641160604	82	46.67	4	77	3	75	3.0e-15	73.7	COG0238	Ribosomal protein S18	75
641160605	152	45.89	4	149	1	146	9.0e-37	146	COG0359	Ribosomal protein L9	148
641160607	577	27.59	50	574	117	646	5.0e-57	215	COG2015	Alkyl sulfatase BDS1 and related hydrolases, metallo-beta-lactamase superfamily	655
641160611	798	22.06	170	432	69	327	2.0e-09	58.5	COG4219	Signal transducer regulating beta-lactamase production, contains  metallopeptidase domain	337
641160612	113	28.32	1	113	12	123	5.0e-16	76.1	COG3682	Predicted transcriptional regulator	123
641160614	1122	19.25	58	403	46	324	5.0e-06	47.3	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
641160615	465	39.81	261	464	24	225	2.0e-52	200	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
641160616	793	50.47	19	746	14	750	0.0e+00	799	COG2183	Transcriptional accessory protein Tex/SPT6	780
641160617	529	31	298	526	1	214	3.0e-29	123	COG2114	Adenylate cyclase, class 3	227
641160619	218	32.6	13	189	1	181	3.0e-19	88.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641160623	958	27.48	86	380	2	285	6.0e-36	146	COG0515	Serine/threonine protein kinase	384
641160624	458	20	63	458	108	553	8.0e-30	125	COG0747	ABC-type transport system, periplasmic component	556
641160625	304	41.03	12	300	2	278	2.0e-52	199	COG2890	Methylase of polypeptide chain release factors	280
641160626	282	52.86	6	232	1	219	2.0e-65	242	COG2884	ABC-type ATPase involved in cell division	223
641160628	1037	29.29	738	1034	7	290	1.0e-37	152	COG2177	Cell division protein FtsX	297
641160629	417	21.92	34	403	24	418	1.0e-19	91.2	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
641160630	507	30.88	189	453	2	279	3.0e-38	153	COG0515	Serine/threonine protein kinase	384
641160632	214	35.75	8	206	19	225	1.0e-25	109	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641160634	108	56.86	5	105	1	102	8.0e-38	148	COG0278	Glutaredoxin-related protein	105
641160636	549	33.54	52	540	5	472	2.0e-87	316	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641160638	596	31.37	203	452	93	334	5.0e-34	139	COG0642	Signal transduction histidine kinase	336
641160641	500	29.12	28	464	6	361	1.0e-50	194	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
641160643	517	31.47	26	517	11	499	4.0e-105	375	COG0442	Prolyl-tRNA synthetase	500
641160644	454	29.91	1	208	33	231	3.0e-15	76.9	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
641160646	279	22.82	49	270	54	280	1.0e-12	67.4	COG1234	Ribonuclease BN, tRNA processing enzyme	292
641160647	409	31.93	9	352	6	339	7.0e-44	171	COG1252	NADH dehydrogenase, FAD-containing subunit	405
641160648	267	43.7	11	259	1	251	1.0e-51	196	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641160650	296	25.36	3	296	118	457	2.0e-20	93.4	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641160652	399	42.52	16	394	4	377	3.0e-103	368	COG1454	Alcohol dehydrogenase, class IV	377
641160663	1064	58.79	5	695	4	664	0.0e+00	881	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
641160664	329	34.43	21	319	8	309	3.0e-61	229	COG1619	Muramoyltetrapeptide carboxypeptidase LdcA (peptidoglycan recycling)	313
641160666	796	28.28	488	776	9	288	3.0e-20	94.1	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
641160668	715	42.25	34	549	9	481	3.0e-125	442	COG0322	Excinuclease UvrABC, nuclease subunit	581
641160669	431	30.32	1	355	3	370	2.0e-41	164	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
641160671	198	49.66	2	142	1	145	5.0e-34	137	COG0629	Single-stranded DNA-binding protein	167
641160672	219	27.33	77	217	7	151	1.0e-08	53.6	COG1714	Uncharacterized membrane protein YckC, RDD family	172
641160675	941	59.6	51	940	11	861	0.0e+00	1148	COG1048	Aconitase A	861
641160677	429	18.42	91	429	42	378	2.0e-06	47.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
641160683	619	27.93	36	475	5	387	1.0e-50	194	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641160687	191	43.1	21	188	1	156	1.0e-40	159	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
641160688	387	45.1	1	386	1	363	5.0e-99	354	COG1932	Phosphoserine aminotransferase	365
641160690	196	42.86	51	196	2	155	4.0e-38	151	COG1225	Peroxiredoxin	157
641160693	526	25.51	40	515	1	469	3.0e-37	150	COG3349	Uncharacterized conserved protein, contains NAD-binding domain and a Fe-S cluster	485
641160695	270	28.95	29	211	1	183	2.0e-16	80	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
641160696	347	38.19	39	320	20	304	4.0e-52	198	COG0010	Arginase family enzyme	305
641160698	270	20.45	6	253	19	279	2.0e-08	53.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641160699	519	23.66	1	421	19	596	1.0e-45	177	COG3211	Secreted phosphatase, PhoX family	616
641160704	226	31.67	3	180	1	179	6.0e-17	81.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641160705	822	28.76	46	318	2	279	3.0e-35	144	COG0515	Serine/threonine protein kinase	384
641160707	394	25.32	12	392	8	388	3.0e-29	123	COG0183	Acetyl-CoA acetyltransferase	392
641160709	597	44.44	1	534	3	530	0.0e+00	566	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
641160711	396	30.32	25	396	31	381	6.0e-32	132	COG5505	Uncharacterized membrane protein	384
641160713	457	26.07	17	435	24	410	1.0e-47	184	COG2124	Cytochrome P450	411
641160718	723	28.74	85	580	47	507	1.0e-48	188	COG3227	Zn-dependent metalloprotease	507
641160726	498	24.25	83	473	17	403	6.0e-33	135	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
641160729	217	34.17	18	212	17	211	2.0e-31	129	COG2013	Uncharacterized conserved protein, AIM24 family	227
641160730	718	45.97	45	716	5	681	0.0e+00	755	COG0339	Zn-dependent oligopeptidase	683
641160733	750	33.63	3	548	4	547	5.0e-90	326	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
641160734	239	37.45	5	237	2	244	4.0e-38	151	COG3279	DNA-binding response regulator, LytR/AlgR family	244
641160737	466	32.04	18	453	14	443	4.0e-62	232	COG0534	Na+-driven multidrug efflux pump	455
641160741	461	18.77	1	399	1	380	3.0e-06	46.8	COG0475	Kef-type K+ transport system, membrane component KefB	397
641160742	477	27.35	228	441	5	225	3.0e-20	93.4	COG0569	Trk K+ transport system, NAD-binding component	225
641160743	482	37.83	1	482	1	488	6.0e-86	311	COG0168	Trk-type K+ transport system, membrane component	499
641160744	1450	24.39	31	432	3	397	2.0e-28	122	COG0475	Kef-type K+ transport system, membrane component KefB	397
641160749	379	34.27	31	377	1	324	1.0e-42	167	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
641160754	151	30.14	1	144	1	131	8.0e-16	76.5	COG0355	FoF1-type ATP synthase, epsilon subunit	135
641160755	540	68.16	49	534	1	468	0.0e+00	750	COG0055	FoF1-type ATP synthase, beta subunit	468
641160756	322	41.51	5	321	1	287	7.0e-71	260	COG0224	FoF1-type ATP synthase, gamma subunit	287
641160757	510	65.08	1	504	1	502	0.0e+00	785	COG0056	FoF1-type ATP synthase, alpha subunit	504
641160758	187	29.19	1	185	2	177	2.0e-25	108	COG0712	FoF1-type ATP synthase, delta subunit	178
641160759	224	32.24	65	216	7	158	1.0e-12	67.2	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
641160760	154	28.47	18	154	6	142	1.0e-08	52.6	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
641160761	116	40.18	2	113	19	130	8.0e-24	102	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
641160764	643	31.54	28	633	1	562	9.0e-86	311	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
641160765	252	28.8	6	250	1	233	2.0e-34	139	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
641160769	241	26.45	4	236	5	240	1.0e-27	116	COG1385	16S rRNA U1498 N3-methylase RsmE	246
641160770	183	26.8	32	183	15	151	6.0e-08	50.9	COG1714	Uncharacterized membrane protein YckC, RDD family	172
641160773	265	35.94	11	264	9	258	1.0e-50	193	COG3228	Mlc titration factor MtfA, regulates ptsG expression	266
641160774	372	41.28	94	370	2	277	9.0e-74	270	COG0077	Prephenate dehydratase	279
641160774	372	49.44	9	96	10	96	4.0e-16	79.2	COG1605	Chorismate mutase	101
641160777	316	27.09	56	304	46	284	9.0e-06	44.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
641160779	210	40.1	1	191	1	194	2.0e-59	222	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
641160786	324	43.9	1	322	1	326	2.0e-61	229	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
641160792	803	28.57	31	318	1	289	1.0e-32	135	COG0515	Serine/threonine protein kinase	384
641160793	226	37.99	6	183	4	177	3.0e-20	92.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641160794	439	16.94	197	438	63	242	1.0e-06	48	COG3591	V8-like Glu-specific endopeptidase	251
641160795	672	31.99	21	488	35	500	2.0e-80	294	COG0513	Superfamily II DNA and RNA helicase	513
641160796	262	40.84	5	261	1	261	6.0e-74	270	COG0708	Exonuclease III	261
641160797	407	43.52	9	405	2	391	2.0e-88	319	COG0183	Acetyl-CoA acetyltransferase	392
641160799	322	28.3	8	303	17	309	1.0e-29	123	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
641160800	1839	22.48	1460	1834	5	362	8.0e-25	110	COG3852	Signal transduction histidine kinase, nitrogen specific	363
641160800	1839	25.42	285	1022	2	746	9.0e-52	200	COG3899	Predicted ATPase	849
641160800	1839	26.35	2	257	8	281	9.0e-31	130	COG0515	Serine/threonine protein kinase	384
641160804	434	23.15	1	434	1	416	2.0e-43	170	COG0443	Molecular chaperone DnaK (HSP70)	579
641160805	696	34.72	7	382	1	347	8.0e-65	242	COG3276	Selenocysteine-specific translation elongation factor	447
641160810	359	29.7	2	353	4	323	2.0e-44	173	COG0523	GTPase, G3E family	323
641160813	405	31.54	171	395	41	275	1.0e-26	114	COG1408	Predicted phosphohydrolase, MPP superfamily	284
641160825	600	31.18	27	541	1	472	5.0e-96	345	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
641160827	280	43.68	3	274	5	281	4.0e-75	274	COG0421	Spermidine synthase	282
641160828	309	32.67	13	304	9	298	6.0e-40	158	COG0010	Arginase family enzyme	305
641160834	420	42.33	15	405	1	392	9.0e-76	277	COG3825	Uncharacterized conserved protein,  contains von Willebrand factor type A (vWA) domain	393
641160835	278	26.77	7	250	23	262	2.0e-31	129	COG0714	MoxR-like ATPase	329
641160837	509	24.44	181	441	45	288	6.0e-22	99.1	COG0642	Signal transduction histidine kinase	336
641160839	197	31.58	13	197	3	186	2.0e-19	88.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
641160843	415	17.35	58	370	38	303	9.0e-09	55.3	COG3547	Transposase	303
641160847	741	39.44	26	737	1	708	0.0e+00	609	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
641160848	554	33.91	7	496	18	525	4.0e-88	319	COG0659	Sulfate permease or related transporter, MFS superfamily	554
641160857	409	22.29	13	332	5	288	9.0e-15	74.9	COG0673	Predicted dehydrogenase	342
641160858	265	40.47	9	259	3	256	6.0e-49	187	COG0300	Short-chain dehydrogenase	265
641160863	388	28.07	20	386	8	320	6.0e-38	152	COG0142	Geranylgeranyl pyrophosphate synthase	322
641160865	1266	23.89	14	292	2	275	4.0e-28	121	COG0515	Serine/threonine protein kinase	384
641160869	373	40.86	10	369	4	358	1.0e-86	313	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
641160872	308	38.01	33	299	34	299	1.0e-47	183	COG1597	Diacylglycerol kinase family enzyme	301
641160875	492	23.92	23	384	1	382	6.0e-29	122	COG0515	Serine/threonine protein kinase	384
641160876	366	28.21	211	365	7	136	3.0e-23	103	COG2210	Peroxiredoxin family protein	137
641160877	158	31.51	14	156	44	187	1.0e-19	89.5	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
641160880	740	17.61	64	740	32	768	7.0e-16	80	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
641160883	126	34.48	1	115	16	131	1.0e-21	94.9	COG0864	Metal-responsive transcriptional regulator, contains CopG/Arc/MetJ DNA-binding domain	136
641160884	875	29.58	390	530	26	152	8.0e-17	83	COG5616	TolB amino-terminal domain (function unknown)	152
641160884	875	31.25	20	283	2	277	5.0e-43	169	COG0515	Serine/threonine protein kinase	384
641160885	651	32.48	60	643	6	551	8.0e-92	331	COG3975	Predicted metalloprotease, contains C-terminal PDZ domain	558
641160888	293	30.3	175	273	1	99	3.0e-06	46.2	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641160894	404	33.91	47	368	17	351	2.0e-48	186	COG1858	Cytochrome c peroxidase	364
641160895	127	53.97	2	127	5	130	1.0e-38	151	COG0103	Ribosomal protein S9	130
641160896	142	47.55	1	142	1	143	9.0e-45	172	COG0102	Ribosomal protein L13	148
641160897	320	27.01	1	308	128	433	3.0e-37	149	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
641160898	311	39.1	11	297	1	279	4.0e-52	198	COG0061	NAD kinase	281
641160899	128	32.41	13	120	7	106	3.0e-13	67.3	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
641160900	1242	23.89	57	388	1	285	1.0e-24	109	COG0515	Serine/threonine protein kinase	384
641160900	1242	34	806	1194	48	444	4.0e-45	177	COG2319	WD40 repeat	466
641160902	187	33.76	1	153	20	176	3.0e-20	91.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641160905	291	32.83	28	291	9	267	3.0e-38	152	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
641160906	324	40.06	10	321	4	299	3.0e-64	238	COG0083	Homoserine kinase	299
641160908	269	35.84	2	269	6	260	1.0e-43	170	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
641160909	322	45.2	2	320	1	313	1.0e-64	240	COG2025	Electron transfer flavoprotein, alpha subunit	313
641160910	679	38.23	310	600	47	333	1.0e-44	175	COG0642	Signal transduction histidine kinase	336
641160912	381	25.41	16	376	42	393	7.0e-35	141	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
641160915	215	36.36	1	215	3	218	3.0e-44	171	COG4122	Predicted O-methyltransferase YrrM	219
641160916	344	42.6	21	344	1	329	3.0e-60	225	COG0714	MoxR-like ATPase	329
641160917	353	27.39	34	326	3	299	3.0e-25	109	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
641160922	200	38.64	21	193	12	185	3.0e-36	145	COG1628	Endonuclease V homolog, UPF0215 family	185
641160924	284	29.2	7	267	2	275	3.0e-17	82.7	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
641160926	275	29.28	17	269	42	304	9.0e-32	130	COG0668	Small-conductance mechanosensitive channel	316
641160929	983	30.49	87	374	2	289	1.0e-38	156	COG0515	Serine/threonine protein kinase	384
641160931	606	29.82	33	294	2	271	2.0e-35	144	COG0515	Serine/threonine protein kinase	384
641160936	947	28.67	63	343	1	281	1.0e-37	152	COG0515	Serine/threonine protein kinase	384
641160940	272	27.62	1	271	1	282	5.0e-21	95.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641160941	380	18.62	35	374	59	380	1.0e-07	51.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
641160944	331	39.09	5	309	3	292	3.0e-67	249	COG1234	Ribonuclease BN, tRNA processing enzyme	292
641160945	488	32.9	6	465	2	453	7.0e-82	298	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
641160948	292	35.18	27	277	2	235	5.0e-45	174	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
641160949	310	39.55	1	307	4	291	5.0e-67	248	COG0685	5,10-methylenetetrahydrofolate reductase	291
641160951	263	32.8	9	257	1	241	8.0e-54	203	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
641160953	498	22.49	53	494	12	404	1.0e-33	137	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
641160958	412	32.75	5	405	1	387	2.0e-57	217	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
641160964	350	21.25	67	294	23	246	1.0e-05	44.1	COG1240	Mg-chelatase subunit ChlD	261
641160967	326	48.02	7	326	9	328	1.0e-68	253	COG0714	MoxR-like ATPase	329
641160969	366	32.64	42	360	10	338	4.0e-44	172	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
641160973	242	24.58	14	191	8	174	6.0e-06	44.6	COG1994	Zn-dependent protease (includes SpoIVFB)	230
641160974	279	46.23	2	200	1	199	5.0e-61	228	COG0177	Endonuclease III	211
641160975	519	47.3	14	492	1	468	7.0e-128	451	COG0606	Predicted ATPase with chaperone activity	490
641160976	573	23.61	125	422	27	328	1.0e-25	111	COG0642	Signal transduction histidine kinase	336
641160979	307	20.62	21	302	10	295	3.0e-14	72.9	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
641160980	299	26.87	33	298	18	277	2.0e-12	67	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641160984	495	37.13	26	493	10	459	1.0e-77	284	COG0277	FAD/FMN-containing dehydrogenase	459
641160985	403	27.52	75	367	35	326	2.0e-13	70.4	COG4886	Leucine-rich repeat (LRR) protein	394
641160986	168	34.06	6	142	1	135	2.0e-14	72.3	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
641160987	482	41.74	1	482	1	450	2.0e-85	310	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
641160988	408	26.94	181	406	3	228	2.0e-07	50.8	COG3770	Murein endopeptidase	284
641160991	267	41.57	1	267	4	264	5.0e-65	241	COG0345	Pyrroline-5-carboxylate reductase	266
641160997	363	21.88	12	332	2	345	3.0e-11	63	COG3424	Predicted naringenin-chalcone synthase	356
641161001	468	19.23	205	468	18	295	1.0e-06	48.5	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
641161002	315	39.09	207	315	15	123	6.0e-14	71.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641161004	140	34.65	12	138	11	133	2.0e-21	94.9	COG0848	Biopolymer transport protein ExbD	137
641161009	267	51.41	7	255	1	245	4.0e-82	297	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
641161010	257	40.16	12	255	4	251	8.0e-55	207	COG0631	Serine/threonine protein phosphatase PrpC	262
641161015	462	37.69	7	462	17	468	1.0e-104	373	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641161016	328	26.94	27	305	5	300	3.0e-17	82.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641161017	310	25.5	18	310	1	295	2.0e-21	97	COG0583	DNA-binding transcriptional regulator, LysR family	297
641161018	376	32.56	23	362	2	318	5.0e-48	185	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
641161019	416	30.75	1	397	1	391	6.0e-61	228	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641161021	260	21.69	1	242	2	193	7.0e-08	51.4	COG0406	Broad specificity phosphatase PhoE	208
641161031	348	41.46	18	343	10	326	2.0e-76	279	COG1171	Threonine dehydratase	347
641161037	416	32.8	1	311	4	304	3.0e-54	206	COG4260	Membrane protease subunit, stomatin/prohibitin family, contains C-terminal Zn-ribbon domain	345
641161040	1052	38.51	155	465	61	378	6.0e-62	233	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
641161044	230	28.07	72	227	1	156	3.0e-18	85.7	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
641161046	449	22.05	2	420	30	440	1.0e-31	131	COG1232	Protoporphyrinogen oxidase	444
641161047	264	19.05	19	263	3	250	7.0e-11	61.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
641161050	577	31.89	22	552	4	511	6.0e-109	388	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
641161053	206	21.35	2	179	11	186	1.0e-05	43.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641161054	214	46.49	1	214	8	235	5.0e-59	220	COG0176	Transaldolase	239
641161056	621	55.99	3	620	1	603	0.0e+00	821	COG1217	Predicted membrane GTPase involved in stress response	603
641161058	753	28.93	81	749	3	618	3.0e-97	349	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
641161060	424	23.8	9	363	1	357	2.0e-37	150	COG0515	Serine/threonine protein kinase	384
641161065	222	25.28	14	187	12	177	7.0e-10	57.7	COG2229	Signal recognition particle receptor subunit beta, a GTPase	187
641161066	371	42.74	1	356	1	359	1.0e-91	330	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
641161067	609	50.17	4	606	6	579	0.0e+00	566	COG0443	Molecular chaperone DnaK (HSP70)	579
641161068	243	36.22	38	220	9	193	9.0e-34	137	COG0576	Molecular chaperone GrpE (heat shock protein)	193
641161069	387	29.89	6	381	5	334	2.0e-41	163	COG1420	Transcriptional regulator of heat shock response	346
641161070	400	34.58	7	400	32	410	2.0e-68	253	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
641161072	492	25.68	12	283	1	277	3.0e-35	143	COG0515	Serine/threonine protein kinase	384
641161075	328	27.41	1	328	1	312	3.0e-29	122	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641161077	473	36.01	2	406	1	398	2.0e-69	256	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
641161080	117	36.67	1	116	4	123	6.0e-24	102	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
641161092	367	46.28	1	365	2	372	1.0e-103	369	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
641161093	128	53.49	1	128	3	131	3.0e-38	150	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
641161094	391	26.24	15	390	5	405	1.0e-53	204	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
641161095	352	23.74	3	331	2	296	3.0e-26	113	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641161098	201	41.71	9	179	1	174	5.0e-19	87.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641161102	239	47.9	5	239	2	229	5.0e-53	201	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641161103	515	30.58	199	515	28	327	3.0e-34	139	COG0642	Signal transduction histidine kinase	336
641161104	224	39.44	8	220	6	201	4.0e-36	145	COG0461	Orotate phosphoribosyltransferase	201
641161108	295	21.23	4	294	37	318	1.0e-19	90.6	COG0385	Predicted Na+-dependent transporter	319
641161113	303	35.62	33	262	1	207	2.0e-44	173	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
641161114	1010	31.5	178	988	3	733	0.0e+00	471	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
641161118	900	45.79	1	899	3	813	0.0e+00	934	COG0495	Leucyl-tRNA synthetase	814
641161123	1503	23.46	1092	1342	14	251	1.0e-14	76.3	COG0714	MoxR-like ATPase	329
641161124	374	39.27	1	372	11	389	9.0e-75	274	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641161125	724	37.52	62	724	14	654	0.0e+00	509	COG3590	Predicted metalloendopeptidase	654
641161126	289	44.14	1	284	4	293	2.0e-73	269	COG1131	ABC-type multidrug transport system, ATPase component	293
641161131	210	23.04	11	210	8	210	2.0e-06	46	COG3714	Uncharacterized membrane protein YhhN	212
641161132	260	22.56	3	253	5	296	2.0e-08	53.4	COG1893	Ketopantoate reductase	307
641161133	309	27.44	42	299	22	282	1.0e-24	107	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641161135	589	25.33	68	441	23	373	1.0e-27	118	COG1680	CubicO group peptidase, beta-lactamase class C family	390
641161137	675	24.47	56	654	18	585	5.0e-51	196	COG4206	Outer membrane cobalamin receptor protein	608
641161141	200	48.95	1	189	1	188	5.0e-62	230	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
641161144	267	26.17	59	267	35	234	2.0e-17	83.4	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
641161145	277	32.62	9	241	3	231	2.0e-40	159	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
641161150	283	46.77	16	276	2	260	3.0e-61	228	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
641161151	722	25.22	329	696	2	447	4.0e-36	146	COG3119	Arylsulfatase A or related enzyme	475
641161158	376	22.87	135	375	63	296	1.0e-16	81.2	COG3921	Uncharacterized conserved protein	300
641161170	872	27.46	61	314	2	279	4.0e-31	130	COG0515	Serine/threonine protein kinase	384
641161171	220	22.47	8	183	2	179	2.0e-16	79	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641161174	211	34.03	1	189	10	193	4.0e-30	124	COG4245	Uncharacterized conserved protein YegL, contains vWA domain of TerY type	207
641161181	1067	22.74	171	452	2	288	8.0e-22	99.8	COG0515	Serine/threonine protein kinase	384
641161189	398	25	71	354	2	286	3.0e-18	86.4	COG4974	Site-specific recombinase XerD	300
641161215	108	36.17	8	100	1	94	2.0e-06	44.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
641161217	174	35.85	16	167	21	179	5.0e-18	84	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641161220	504	30.39	73	332	2	279	6.0e-32	132	COG0515	Serine/threonine protein kinase	384
641161221	192	23.57	30	180	27	181	2.0e-07	48.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641161222	125	33.87	16	77	4	65	1.0e-06	45.6	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
641161228	341	27.6	86	277	46	220	1.0e-09	57.3	COG2801	Transposase InsO and inactivated derivatives	232
641161241	363	26.84	93	350	45	297	3.0e-19	89.5	COG4974	Site-specific recombinase XerD	300
641161243	415	26.73	9	399	7	402	1.0e-43	171	COG3464	Transposase	402
641161245	401	29.88	9	346	7	324	2.0e-46	179	COG0270	Site-specific DNA-cytosine methylase	328
641161249	452	18	6	431	2	435	4.0e-28	119	COG0612	Predicted Zn-dependent peptidase	438
641161250	445	24.26	15	440	1	436	1.0e-34	141	COG0612	Predicted Zn-dependent peptidase	438
641161253	185	27.38	20	182	18	181	2.0e-06	45.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641161254	505	28.62	74	338	2	281	9.0e-33	135	COG0515	Serine/threonine protein kinase	384
641161273	361	29.89	103	344	45	294	2.0e-22	100	COG4974	Site-specific recombinase XerD	300
641161274	404	27.91	13	398	9	405	9.0e-47	181	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
641161275	332	32.33	1	330	9	320	8.0e-64	237	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
641161277	356	27.97	1	353	2	322	1.0e-39	157	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
641161283	366	22.9	15	272	3	253	3.0e-14	72.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
641161287	325	37.5	2	324	15	325	3.0e-64	238	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
641161289	133	38.35	11	131	17	149	2.0e-08	52	COG1714	Uncharacterized membrane protein YckC, RDD family	172
641161292	307	24.16	14	278	63	323	7.0e-29	121	COG2845	Uncharacterized protein	354
641161293	467	24.6	238	465	2	229	5.0e-07	49.6	COG3770	Murein endopeptidase	284
641161295	465	42.04	77	463	12	395	2.0e-56	213	COG1921	Seryl-tRNA(Sec) selenium transferase	395
641161299	192	38.99	3	161	2	153	1.0e-38	152	COG0242	Peptide deformylase	168
641161301	294	25	1	249	5	213	2.0e-15	76.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641161302	427	29.8	37	427	32	393	7.0e-45	175	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
641161305	211	26.11	21	209	15	209	2.0e-12	66	COG0625	Glutathione S-transferase	211
641161306	307	37.38	1	303	22	305	4.0e-51	195	COG0010	Arginase family enzyme	305
641161309	244	25.21	5	237	6	227	6.0e-19	88	COG1011	FMN phosphatase YigB, HAD superfamily	229
641161310	231	27.9	1	228	3	198	4.0e-24	105	COG1573	Uracil-DNA glycosylase	202
641161312	204	33.89	2	176	1	180	7.0e-20	90.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641161317	577	19.09	68	385	50	357	8.0e-16	79	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
641161318	445	39.78	12	445	6	454	2.0e-91	329	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
641161320	175	42.57	25	172	60	205	7.0e-33	133	COG1847	Predicted RNA-binding protein Jag, conains KH and R3H domains	208
641161321	580	32.8	264	565	7	301	2.0e-58	220	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
641161323	195	34.59	6	137	1	105	1.0e-12	66.8	COG0594	RNase P protein component	117
641161325	453	45.07	5	448	1	407	1.0e-118	420	COG0593	Chromosomal replication initiation ATPase DnaA	408
641161326	135	29.46	24	134	20	129	2.0e-11	61.8	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
641161327	304	32.88	7	297	3	291	2.0e-36	146	COG0583	DNA-binding transcriptional regulator, LysR family	297
641161329	534	47.45	1	534	29	575	0.0e+00	590	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
641161330	343	55.86	1	333	3	335	0.0e+00	463	COG0059	Ketol-acid reductoisomerase	338
641161331	553	51.27	1	544	2	549	0.0e+00	603	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
641161333	349	45.12	25	349	5	332	2.0e-80	292	COG1171	Threonine dehydratase	347
641161334	550	27.54	6	357	1	357	2.0e-36	147	COG0515	Serine/threonine protein kinase	384
641161338	467	46.05	17	467	12	435	0.0e+00	495	COG0017	Aspartyl/asparaginyl-tRNA synthetase	435
641161340	533	27.95	77	355	2	279	2.0e-37	150	COG0515	Serine/threonine protein kinase	384
641161341	458	45.88	45	396	10	371	9.0e-91	327	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
641161342	319	31.45	2	266	18	297	5.0e-33	135	COG1397	ADP-ribosylglycohydrolase	314
641161343	602	20.27	6	557	1	541	1.0e-33	138	COG2303	Choline dehydrogenase or related flavoprotein	542
641161345	220	32.97	3	178	1	182	2.0e-22	99	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641161355	368	41.37	1	362	19	344	4.0e-83	301	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
641161356	287	34.35	26	283	4	254	2.0e-41	163	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
641161360	472	20.2	1	378	38	391	2.0e-31	130	COG1524	Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily	450
641161361	296	36.19	3	259	2	254	2.0e-71	262	COG1099	Predicted metal-dependent hydrolase, TIM-barrel fold	254
641161363	708	21.72	430	678	23	289	2.0e-11	64.9	COG0382	4-hydroxybenzoate polyprenyltransferase	289
641161364	407	30.46	33	402	12	358	4.0e-65	242	COG0337	3-dehydroquinate synthetase	360
641161366	352	44.51	5	322	2	309	3.0e-78	285	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
641161370	273	45.63	1	241	1	248	2.0e-69	256	COG4422	Bacteriophage protein gp37	250
641161371	834	30.13	116	406	2	305	3.0e-44	174	COG0515	Serine/threonine protein kinase	384
641161372	602	29.06	3	586	19	682	2.0e-82	300	COG1298	Flagellar biosynthesis pathway, component FlhA	696
641161377	580	43.48	1	272	8	279	2.0e-72	267	COG3220	Uncharacterized conserved protein, UPF0276 family	282
641161380	836	27.49	7	405	1	385	2.0e-48	187	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
641161380	836	36.43	434	836	1	379	6.0e-81	295	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
641161381	191	36.48	29	186	55	204	8.0e-28	117	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
641161383	566	40.18	16	445	9	403	3.0e-82	299	COG4402	Uncharacterized protein	457
641161388	439	25.9	1	284	13	284	4.0e-21	96.4	COG0515	Serine/threonine protein kinase	384
641161392	209	39.39	4	198	9	204	1.0e-42	166	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
641161393	223	53.7	5	219	2	217	3.0e-65	241	COG0087	Ribosomal protein L3	218
641161394	280	47.45	17	270	3	256	3.0e-79	288	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
641161400	422	23.29	162	386	66	348	7.0e-08	52.3	COG4188	Predicted dienelactone hydrolase	365
641161403	395	19.44	23	316	34	342	7.0e-07	48.7	COG0738	Fucose permease	422
641161405	179	28.73	8	178	29	202	8.0e-19	86.9	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
641161407	221	32.75	2	213	55	279	5.0e-09	54.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641161408	530	41.05	8	529	14	527	5.0e-111	395	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641161409	257	43.89	1	254	1	251	2.0e-44	173	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641161410	350	24.56	5	343	2	323	3.0e-34	139	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
641161412	358	24.41	18	354	11	280	5.0e-13	69	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641161414	452	26.51	5	406	7	405	5.0e-32	132	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
641161416	275	21.14	18	243	33	275	5.0e-10	58.6	COG3239	Fatty acid desaturase	343
641161419	621	24.94	44	415	38	395	1.0e-14	75	COG1404	Serine protease, subtilisin family	508
641161423	548	32.38	106	544	24	463	1.0e-46	181	COG2027	D-alanyl-D-alanine carboxypeptidase	470
641161425	456	42.16	3	455	1	426	7.0e-126	444	COG0172	Seryl-tRNA synthetase	429
641161430	383	30.36	37	249	4	224	2.0e-29	123	COG0705	Membrane associated serine protease, rhomboid family	228
641161433	342	27.24	53	338	23	277	3.0e-11	62.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641161434	614	41.93	23	588	4	572	0.0e+00	553	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
641161436	91	45.35	5	90	2	87	3.0e-20	89.9	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
641161437	158	25	30	152	2	123	1.0e-08	53	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
641161440	304	50.17	1	284	1	285	9.0e-84	303	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
641161441	344	40.45	6	313	2	306	1.0e-73	270	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
641161442	200	36.17	1	93	10	103	6.0e-16	77.6	COG1544	Ribosome-associated translation inhibitor RaiA	110
641161443	518	37.84	3	518	1	444	2.0e-104	373	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
641161444	545	62.24	10	542	1	533	0.0e+00	847	COG0504	CTP synthase (UTP-ammonia lyase)	533
641161446	510	53.78	8	507	2	493	0.0e+00	617	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
641161455	381	33.04	260	371	2	113	1.0e-12	67.7	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641161460	743	27.56	144	612	10	458	1.0e-38	155	COG5002	Signal transduction histidine kinase	459
641161461	408	19.86	3	406	7	379	4.0e-14	73	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
641161465	278	22.96	24	271	50	302	1.0e-17	84.2	COG0501	Zn-dependent protease with chaperone function	302
641161466	268	25	61	263	12	207	5.0e-17	81.9	COG0400	Predicted esterase	207
641161468	170	40.61	4	165	29	192	8.0e-35	139	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
641161470	188	40.22	3	173	1	179	6.0e-25	107	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641161473	526	24.54	2	413	41	586	8.0e-46	178	COG3211	Secreted phosphatase, PhoX family	616
641161475	285	26.94	1	192	13	146	1.0e-19	90.8	COG2131	Deoxycytidylate deaminase	164
641161478	201	34.12	6	173	11	178	1.0e-19	89.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641161481	941	32.08	57	329	2	279	2.0e-37	151	COG0515	Serine/threonine protein kinase	384
641161483	1898	24.09	286	1116	2	828	4.0e-74	274	COG3899	Predicted ATPase	849
641161488	253	26.27	1	236	2	237	4.0e-17	82.3	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
641161491	228	29.44	2	226	9	248	8.0e-18	84.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641161494	408	27.6	40	222	52	243	5.0e-13	69.2	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
641161496	362	35.14	242	352	3	113	4.0e-15	75.8	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641161498	304	31.41	3	303	59	344	4.0e-43	168	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
641161499	481	29.52	278	480	18	216	7.0e-25	108	COG2114	Adenylate cyclase, class 3	227
641161503	399	43.97	5	399	7	397	0.0e+00	466	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
641161505	383	34.19	265	381	1	117	2.0e-17	83.9	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641161511	192	53.16	4	192	7	196	2.0e-67	248	COG0529	Adenylylsulfate kinase or related kinase	197
641161515	147	39.35	1	145	1	154	3.0e-32	130	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
641161516	243	28.46	11	133	2	112	3.0e-17	82.6	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
641161518	305	29.31	14	303	3	254	2.0e-18	86.6	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
641161519	315	32.29	16	298	12	291	5.0e-48	184	COG0258	5'-3' exonuclease	310
641161525	182	26.47	19	152	15	140	7.0e-14	70.3	COG1510	DNA-binding transcriptional regulator GbsR, MarR family	177
641161528	367	20	13	366	12	400	4.0e-15	76.2	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
641161530	385	33.16	1	385	2	373	2.0e-74	273	COG4637	Predicted ATPase	373
641161531	173	24.22	6	159	3	154	4.0e-12	64.5	COG0563	Adenylate kinase or related kinase	178
641161532	304	33.86	60	304	15	238	3.0e-44	172	COG4798	Predicted methyltransferase	238
641161534	236	25.76	6	231	1	192	2.0e-13	69.5	COG0625	Glutathione S-transferase	211
641161536	314	29.02	109	314	95	317	6.0e-22	98.5	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
641161540	405	42.29	10	380	1	322	2.0e-88	319	COG0523	GTPase, G3E family	323
641161541	263	30.42	1	260	13	269	1.0e-42	167	COG2503	Predicted secreted acid phosphatase	274
641161543	1260	31.74	832	1215	57	447	5.0e-45	177	COG2319	WD40 repeat	466
641161546	365	40.36	3	333	1	334	2.0e-78	286	COG1816	Adenosine deaminase	345
641161547	479	34.3	11	453	1	433	2.0e-91	330	COG0015	Adenylosuccinate lyase	438
641161548	392	25.31	66	383	8	302	3.0e-30	126	COG0010	Arginase family enzyme	305
641161549	201	36.65	2	162	25	175	1.0e-30	126	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641161552	583	51.12	204	560	2	355	4.0e-103	369	COG2262	50S ribosomal subunit-associated GTPase HflX	411
641161554	420	29.19	1	333	5	345	9.0e-40	158	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
641161555	399	42.86	4	323	10	324	8.0e-69	254	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
641161561	352	25.09	68	350	34	295	2.0e-15	77	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
641161562	486	28.39	5	484	16	537	8.0e-55	208	COG0405	Gamma-glutamyltranspeptidase	539
641161565	306	33.22	7	300	1	297	3.0e-32	132	COG0583	DNA-binding transcriptional regulator, LysR family	297
641161566	219	22.45	14	111	19	113	5.0e-07	48.3	COG1917	Cupin domain protein related to quercetin dioxygenase	131
641161568	274	36.4	8	268	3	255	1.0e-39	157	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641161571	402	38.56	10	401	2	390	6.0e-89	321	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
641161572	193	42.49	1	191	1	187	3.0e-36	145	COG0742	16S rRNA G966 N2-methylase RsmD	187
641161577	1315	30.18	95	351	2	274	1.0e-40	162	COG0515	Serine/threonine protein kinase	384
641161582	339	36.65	10	328	1	289	2.0e-69	256	COG1131	ABC-type multidrug transport system, ATPase component	293
641161587	296	22.15	128	279	2	127	8.0e-07	47.9	COG0394	Protein-tyrosine-phosphatase	139
641161589	169	54.61	1	152	32	180	4.0e-51	193	COG2818	3-methyladenine DNA glycosylase Tag	188
641161594	538	17.4	38	481	4	397	1.0e-19	91.6	COG2067	Long-chain fatty acid transport protein	440
641161603	1901	25.33	299	1110	2	767	4.0e-68	254	COG3899	Predicted ATPase	849
641161605	636	25.3	1	405	5	403	2.0e-32	134	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
641161612	182	30.73	1	172	11	188	2.0e-26	111	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
641161614	374	29.04	76	343	1	253	7.0e-34	138	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
641161615	342	44.68	18	340	6	325	4.0e-65	241	COG0714	MoxR-like ATPase	329
641161619	511	19.27	1	407	17	366	6.0e-11	62.8	COG0644	Dehydrogenase (flavoprotein)	396
641161620	427	25.29	2	342	7	313	3.0e-28	119	COG0644	Dehydrogenase (flavoprotein)	396
641161622	444	27.9	9	425	5	399	4.0e-44	172	COG2124	Cytochrome P450	411
641161625	367	25.83	71	338	25	275	2.0e-14	73.4	COG1398	Fatty-acid desaturase	289
641161626	473	50.96	7	473	3	454	0.0e+00	548	COG1066	Predicted ATP-dependent serine protease	456
641161628	379	33.6	129	379	82	330	5.0e-30	125	COG0642	Signal transduction histidine kinase	336
641161629	223	50.67	4	218	2	225	1.0e-51	196	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641161637	2166	27.68	2049	2159	33	138	6.0e-13	71.8	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
641161638	965	31.31	491	698	36	238	2.0e-06	48.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641161639	1179	33.13	10	998	1	910	0.0e+00	529	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
641161640	516	22.29	58	371	4	281	2.0e-28	120	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
641161641	436	33.49	2	424	19	410	5.0e-54	205	COG2124	Cytochrome P450	411
641161645	445	19.77	9	441	1	391	2.0e-17	84.1	COG2814	Predicted arabinose efflux permease, MFS family	394
641161646	401	22.01	43	396	44	389	6.0e-15	75.6	COG2814	Predicted arabinose efflux permease, MFS family	394
641161648	215	32.54	3	206	7	209	6.0e-32	130	COG2102	Diphthamide synthase (EF-2-diphthine--ammonia ligase)	223
641161653	764	22.03	1	361	3	376	4.0e-29	123	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
641161653	764	41	398	752	4	352	3.0e-97	350	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
641161655	275	34.35	5	260	6	260	2.0e-50	192	COG0631	Serine/threonine protein phosphatase PrpC	262
641161660	470	35.23	19	469	6	462	2.0e-91	329	COG2211	Na+/melibiose symporter or related transporter	467
641161663	571	39.19	1	561	1	509	1.0e-127	450	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
641161664	177	37.75	29	176	16	166	2.0e-26	111	COG3749	Uncharacterized conserved protein, DUF934 family	167
641161668	1102	15.29	430	1102	177	768	1.0e-06	49.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
641161669	178	29.23	10	139	2	120	6.0e-12	64.1	COG0848	Biopolymer transport protein ExbD	137
641161670	151	31.88	8	145	6	137	8.0e-20	89.9	COG0848	Biopolymer transport protein ExbD	137
641161671	211	34.15	2	204	6	210	2.0e-27	115	COG0811	Biopolymer transport protein ExbB/TolQ	216
641161672	279	21.19	45	279	29	244	1.0e-05	44	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
641161680	214	32	9	180	2	176	1.0e-19	90.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641161681	995	26.15	58	362	2	289	5.0e-35	143	COG0515	Serine/threonine protein kinase	384
641161687	254	28.46	8	252	7	255	1.0e-33	136	COG0300	Short-chain dehydrogenase	265
641161689	195	29.48	2	163	1	171	1.0e-18	86.2	COG0431	NAD(P)H-dependent FMN reductase	184
641161690	370	26.76	71	362	14	308	1.0e-34	141	COG0668	Small-conductance mechanosensitive channel	316
641161692	520	51.5	13	512	8	497	0.0e+00	508	COG2986	Histidine ammonia-lyase	498
641161693	657	23.72	170	543	2	383	3.0e-39	157	COG0515	Serine/threonine protein kinase	384
641161694	573	30.9	34	307	2	282	6.0e-43	169	COG0515	Serine/threonine protein kinase	384
641161696	1390	32.55	148	656	21	513	9.0e-96	345	COG0513	Superfamily II DNA and RNA helicase	513
641161700	623	34.06	103	621	21	549	2.0e-105	376	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
641161703	613	29.79	11	280	1	287	2.0e-41	164	COG0515	Serine/threonine protein kinase	384
641161704	639	33.44	20	639	16	609	4.0e-127	449	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
641161706	590	54.26	23	585	26	579	0.0e+00	692	COG0441	Threonyl-tRNA synthetase	589
641161707	217	50.65	1	154	23	176	3.0e-50	191	COG0290	Translation initiation factor IF-3	176
641161708	67	54.69	1	64	1	64	1.0e-09	54.8	COG0291	Ribosomal protein L35	65
641161709	117	58.12	1	117	1	117	3.0e-30	123	COG0292	Ribosomal protein L20	118
641161710	366	43.58	10	363	7	335	5.0e-104	371	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
641161711	851	33.14	166	841	10	645	3.0e-108	386	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
641161712	94	41.94	1	93	2	93	2.0e-24	104	COG0776	Bacterial nucleoid DNA-binding protein	94
641161713	218	24	59	158	1	99	2.0e-10	59.4	COG0789	DNA-binding transcriptional regulator, MerR family	124
641161716	218	46.12	3	210	31	245	9.0e-52	196	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
641161717	191	47.5	21	180	7	164	1.0e-38	152	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
641161718	348	26.15	6	327	3	301	2.0e-33	136	COG1893	Ketopantoate reductase	307
641161720	142	41.74	18	132	4	118	8.0e-23	99.5	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
641161724	536	24.95	47	501	4	459	4.0e-29	123	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
641161727	354	32.14	27	296	9	254	4.0e-32	132	COG3741	N-formylglutamate amidohydrolase	272
641161729	598	45.52	62	595	14	537	0.0e+00	544	COG0405	Gamma-glutamyltranspeptidase	539
641161735	106	46.43	6	88	5	88	2.0e-23	100	COG0271	Stress-induced morphogen (activity unknown)	90
641161736	764	26.53	389	752	22	388	2.0e-52	201	COG0247	Fe-S oxidoreductase	388
641161739	182	30.06	13	175	1	161	2.0e-20	92.6	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
641161740	376	36.24	5	373	6	370	3.0e-66	245	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
641161741	691	29.03	287	557	77	336	2.0e-30	127	COG0642	Signal transduction histidine kinase	336
641161744	609	66.44	14	609	7	602	0.0e+00	988	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
641161750	203	21.57	1	193	2	199	4.0e-15	74.5	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
641161752	210	40.78	1	202	5	189	6.0e-38	150	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
641161753	626	31.36	9	274	2	277	2.0e-42	167	COG0515	Serine/threonine protein kinase	384
641161754	399	22.22	13	345	1	331	3.0e-31	129	COG0515	Serine/threonine protein kinase	384
641161758	305	36.18	1	292	2	299	7.0e-48	184	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
641161759	166	32.43	19	160	13	153	4.0e-19	87.7	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
641161762	332	43.98	1	327	19	347	2.0e-87	316	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
641161766	407	35.28	18	381	20	420	2.0e-68	253	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
641161767	230	62.72	2	229	59	286	3.0e-91	328	COG0777	Acetyl-CoA carboxylase beta subunit	294
641161769	357	52.21	6	342	4	337	2.0e-109	389	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
641161771	1324	27.72	49	330	2	300	9.0e-37	149	COG0515	Serine/threonine protein kinase	384
641161772	532	18.95	6	519	3	486	4.0e-09	56.6	COG1233	Phytoene dehydrogenase-related protein	487
641161774	121	37.39	1	114	6	119	3.0e-18	84.2	COG2346	Truncated hemoglobin YjbI	133
641161775	340	26.64	98	324	5	211	1.0e-25	110	COG0543	NAD(P)H-flavin reductase	252
641161783	312	24.16	1	296	1	279	1.0e-13	70.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641161787	263	46.46	1	225	1	222	4.0e-72	264	COG1136	ABC-type lipoprotein export system, ATPase component	226
641161788	141	46.88	4	129	2	129	3.0e-32	131	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
641161790	300	21.14	19	284	8	296	4.0e-15	75.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641161793	94	46.3	1	50	13	66	1.0e-10	58.3	COG1983	Phage shock protein PspC (stress-responsive transcriptional regulator)	70
641161796	159	48.03	8	159	1	152	3.0e-44	171	COG0691	tmRNA-binding protein	153
641161807	579	48.15	2	578	8	621	0.0e+00	702	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
641161809	631	29.45	493	628	13	153	8.0e-11	62.6	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
641161809	631	37.79	2	470	9	457	6.0e-103	368	COG0773	UDP-N-acetylmuramate-alanine ligase	459
641161811	113	34.12	1	85	1	85	4.0e-10	56.6	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
641161812	800	20.53	7	561	1	481	7.0e-12	66.5	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
641161813	583	27.04	12	521	5	478	6.0e-40	159	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
641161814	642	25.52	8	579	1	473	4.0e-24	106	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
641161815	430	41.15	11	408	1	394	6.0e-97	348	COG0019	Diaminopimelate decarboxylase	394
641161816	121	29.41	12	107	14	112	2.0e-08	51.1	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
641161819	458	28.57	295	447	36	189	6.0e-29	122	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
641161822	282	44.24	5	277	7	284	6.0e-56	211	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
641161823	386	28.45	10	351	1	335	2.0e-38	153	COG0349	Ribonuclease D	361
641161825	559	25.82	362	538	21	190	6.0e-08	53	COG0400	Predicted esterase	207
641161825	559	27.89	1	322	23	377	7.0e-51	195	COG1454	Alcohol dehydrogenase, class IV	377
641161826	444	43.33	13	398	4	383	8.0e-88	317	COG3508	Homogentisate 1,2-dioxygenase	427
641161828	551	32.43	1	547	2	530	3.0e-112	399	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641161830	640	28.41	207	634	37	443	1.0e-41	165	COG1793	ATP-dependent DNA ligase	444
641161833	463	29.34	141	454	31	334	2.0e-26	114	COG0642	Signal transduction histidine kinase	336
641161834	229	42.36	6	225	2	229	7.0e-49	187	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641161835	279	30.77	1	279	6	263	2.0e-42	166	COG0300	Short-chain dehydrogenase	265
641161841	1928	25.99	287	971	2	662	7.0e-66	247	COG3899	Predicted ATPase	849
641161842	273	26.48	1	245	2	252	1.0e-29	124	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641161849	431	18.22	181	399	1	232	6.0e-11	62.3	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
641161852	743	35.56	1	329	1	326	4.0e-63	236	COG1796	DNA polymerase/3'-5' exonuclease PolX	326
641161854	289	33.33	51	288	51	312	1.0e-31	130	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641161863	503	28.51	10	489	8	493	2.0e-42	167	COG0591	Na+/proline symporter	493
641161864	642	24.47	58	631	23	574	5.0e-26	113	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
641161865	209	31.5	12	194	3	196	3.0e-16	78.7	COG0406	Broad specificity phosphatase PhoE	208
641161868	1125	35.22	1	1102	1	1062	0.0e+00	925	COG0587	DNA polymerase III, alpha subunit	1139
641161871	173	27.91	1	172	8	179	7.0e-18	83.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641161875	507	27.62	33	293	14	293	4.0e-29	123	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
641161876	1381	42.18	39	1152	1	1060	0.0e+00	759	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
641161877	4273	25.71	3795	3996	7	214	6.0e-10	62.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641161877	4273	34.77	3474	3786	6	326	2.0e-47	187	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
641161877	4273	41.74	2077	3152	4	1032	0.0e+00	836	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
641161880	342	27.3	9	327	7	326	2.0e-24	107	COG0642	Signal transduction histidine kinase	336
641161881	229	42.86	4	226	1	229	2.0e-47	182	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641161882	492	34.23	59	490	8	446	1.0e-60	227	COG1231	Monoamine oxidase	450
641161883	813	34.17	63	809	27	747	0.0e+00	468	COG3537	Putative alpha-1,2-mannosidase	768
641161884	352	29.53	8	334	5	332	7.0e-42	164	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
641161885	512	34.63	9	510	6	474	9.0e-93	334	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
641161887	214	34.45	4	212	1	190	1.0e-30	126	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
641161888	552	30.11	9	552	1	522	3.0e-92	333	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
641161893	262	35.43	76	247	67	240	1.0e-24	107	COG1360	Flagellar motor protein MotB	244
641161894	998	33.99	298	997	209	855	3.0e-120	426	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
641161895	255	25.65	60	250	25	205	9.0e-18	83.9	COG2834	Outer membrane lipoprotein-sorting protein	211
641161899	293	35.16	170	260	2	92	2.0e-11	63.5	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641161902	445	23.64	34	418	40	390	4.0e-06	46.7	COG2814	Predicted arabinose efflux permease, MFS family	394
641161906	165	37.97	3	160	1	157	3.0e-30	124	COG1329	RNA polymerase-interacting regulator, CarD/CdnL/TRCF family	166
641161908	524	49.71	2	520	13	511	0.0e+00	553	COG0029	Aspartate oxidase	518
641161914	241	33.84	25	219	2	192	1.0e-23	103	COG0558	Phosphatidylglycerophosphate synthase	192
641161915	405	35.08	62	400	105	449	2.0e-75	276	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
641161921	257	28.02	21	202	15	158	4.0e-24	105	COG0597	Lipoprotein signal peptidase	167
641161922	159	31.82	1	152	2	154	5.0e-21	94.2	COG2062	Phosphohistidine phosphatase SixA	163
641161923	216	24.4	10	216	5	163	6.0e-17	81	COG0597	Lipoprotein signal peptidase	167
641161926	657	15.69	132	579	91	532	8.0e-07	49.3	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
641161928	219	35.21	4	74	5	74	7.0e-12	64.2	COG3592	Uncharacterized Fe-S cluster protein YjdI	74
641161936	448	42.56	12	438	3	401	7.0e-113	401	COG0162	Tyrosyl-tRNA synthetase	401
641161939	311	43.38	1	291	1	298	7.0e-73	267	COG0216	Protein chain release factor A	363
641161945	332	54.01	1	320	1	324	4.0e-121	428	COG0435	Glutathionyl-hydroquinone reductase	324
641161952	822	28.15	4	290	2	282	1.0e-39	158	COG0515	Serine/threonine protein kinase	384
641161953	318	28	168	292	1	118	9.0e-09	54.5	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
641161956	788	43.53	240	788	2	507	1.0e-130	461	COG0532	Translation initiation factor IF-2, a GTPase	509
641161957	366	33.33	5	325	2	310	3.0e-60	226	COG0167	Dihydroorotate dehydrogenase	310
641161961	240	32.31	30	158	33	131	2.0e-16	79.6	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
641161965	74	32.81	10	73	1	64	4.0e-06	43	COG3205	Uncharacterized membrane protein	72
641161973	106	31.78	1	106	1	105	2.0e-14	70.7	COG1965	Iron-binding protein CyaY, frataxin homolog	106
641161975	182	50.62	4	163	2	159	6.0e-36	143	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
641161977	211	34.13	15	178	11	177	5.0e-22	97.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641161979	1224	26.23	65	352	2	281	7.0e-37	150	COG0515	Serine/threonine protein kinase	384
641161984	512	22.67	68	509	29	403	2.0e-31	130	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
641161985	235	30.85	25	225	12	212	1.0e-27	116	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
641161987	388	32.23	2	387	11	388	1.0e-54	207	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
641161988	311	29.64	5	309	4	293	9.0e-40	157	COG1597	Diacylglycerol kinase family enzyme	301
641161990	578	20.92	138	500	2	341	3.0e-17	83.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641161992	653	32.55	23	302	1	290	8.0e-44	172	COG0515	Serine/threonine protein kinase	384
641161993	337	28.95	48	336	2	297	8.0e-38	151	COG0515	Serine/threonine protein kinase	384
641161994	322	33.33	10	300	6	289	3.0e-53	202	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
641161995	364	26.53	75	362	40	298	2.0e-19	89.9	COG2813	16S rRNA G1207 methylase RsmC	300
641161996	1047	32.22	372	1035	117	864	3.0e-90	327	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
641161997	131	26.62	1	127	1	139	2.0e-09	54.6	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
641161999	406	38.78	12	353	1	315	2.0e-74	272	COG0042	tRNA-dihydrouridine synthase	323
641162002	162	52.26	5	159	3	156	2.0e-46	178	COG0315	Molybdenum cofactor biosynthesis enzyme	157
641162004	405	41.56	1	305	8	305	1.0e-72	267	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
641162009	292	33.87	21	268	5	249	1.0e-53	203	COG0805	Sec-independent protein secretion pathway component TatC	255
641162011	212	27.27	1	88	1	86	9.0e-06	43.8	COG1826	Sec-independent protein translocase protein TatA	94
641162013	226	26.72	1	221	2	218	2.0e-21	96.4	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
641162014	458	27.21	43	456	30	406	1.0e-47	184	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
641162018	235	25.63	9	205	27	208	1.0e-20	93.5	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
641162019	435	31.64	6	425	5	404	5.0e-63	235	COG1078	HD superfamily phosphohydrolase	421
641162020	1419	29.48	1077	1333	4	271	6.0e-11	64.2	COG0457	Tetratricopeptide (TPR) repeat	291
641162021	268	36.74	7	266	1	259	7.0e-50	190	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
641162025	202	44.66	3	197	6	200	5.0e-60	224	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
641162026	254	42.97	1	254	2	238	2.0e-58	219	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
641162027	266	62.69	1	260	2	256	3.0e-100	358	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
641162028	242	40.66	140	230	4	89	4.0e-12	65.2	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
641162028	242	54.08	14	110	14	111	1.0e-37	149	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
641162029	202	39.18	1	189	1	194	1.0e-33	136	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
641162032	369	67.21	1	369	1	366	0.0e+00	564	COG1062	Zn-dependent alcohol dehydrogenase	366
641162033	234	29.49	4	196	10	225	2.0e-19	89.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641162034	421	36.83	46	371	13	364	1.0e-72	267	COG1858	Cytochrome c peroxidase	364
641162036	872	57.97	32	599	3	556	0.0e+00	775	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
641162037	406	36	1	400	1	361	1.0e-68	254	COG1195	Recombinational DNA repair ATPase RecF	363
641162038	372	31.64	1	372	1	364	3.0e-63	235	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
641162040	444	22.09	2	420	1	382	8.0e-33	135	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
641162043	320	29.46	195	306	2	113	3.0e-09	56.6	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641162047	394	45.34	72	392	30	335	3.0e-78	286	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
641162048	421	66.01	13	421	1	409	0.0e+00	638	COG2871	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF	410
641162049	199	69.04	3	199	2	198	7.0e-66	243	COG2209	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE	198
641162050	207	64.68	6	206	8	208	1.0e-73	269	COG1347	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD	208
641162051	298	42.41	4	257	7	260	3.0e-65	242	COG2869	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC	264
641162052	422	51.49	4	402	2	399	1.0e-103	370	COG1805	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB	400
641162053	459	54.17	5	459	3	447	0.0e+00	527	COG1726	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA	447
641162054	351	39.42	1	342	2	325	5.0e-74	271	COG1171	Threonine dehydratase	347
641162057	742	33.02	199	735	167	776	2.0e-86	314	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
641162060	491	27.03	4	172	1	173	2.0e-18	87.6	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
641162060	491	30.28	270	483	71	277	2.0e-11	64.3	COG5495	Predicted oxidoreductase, contains short-chain dehydrogenase (SDR) and DUF2520 domains	289
641162062	218	21.6	58	217	2	161	3.0e-09	55.3	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
641162068	491	54.7	14	491	3	444	0.0e+00	576	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
641162069	179	56.5	1	177	1	177	8.0e-62	229	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
641162070	202	45.45	14	197	1	182	7.0e-51	193	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
641162075	182	36.72	3	177	1	175	1.0e-22	99.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641162076	243	26.81	4	236	3	210	4.0e-15	75	COG3806	Anti-sigma factor ChrR, cupin superfamily	216
641162077	933	47.37	328	932	10	593	0.0e+00	609	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
641162079	279	31.56	17	277	46	298	2.0e-30	126	COG0668	Small-conductance mechanosensitive channel	316
641162081	437	30.28	2	252	5	277	1.0e-32	134	COG0515	Serine/threonine protein kinase	384
641162082	375	25.08	69	368	73	379	6.0e-21	95.4	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
641162085	203	54.82	1	197	9	205	6.0e-61	227	COG0572	Uridine kinase	218
641162086	268	20.45	2	264	26	280	4.0e-15	75.5	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
641162090	325	36.03	78	324	24	253	1.0e-43	170	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
641162091	568	21.27	263	552	12	316	2.0e-10	60.9	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641162094	322	26.69	24	293	1	308	7.0e-22	98.3	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641162095	433	36.05	1	253	6	250	2.0e-46	180	COG0631	Serine/threonine protein phosphatase PrpC	262
641162096	1255	44.35	14	1244	3	1130	0.0e+00	1198	COG0587	DNA polymerase III, alpha subunit	1139
641162097	197	26.32	35	129	26	116	2.0e-06	46.2	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
641162099	858	23.76	57	440	2	367	2.0e-33	138	COG0515	Serine/threonine protein kinase	384
641162102	465	21.81	9	280	4	306	6.0e-06	45.8	COG5640	Secreted trypsin-like serine protease	413
641162106	1165	31.79	1	558	30	533	7.0e-78	286	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
641162108	97	43	1	97	1	97	3.0e-09	53.4	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
641162110	139	50.38	1	133	2	134	3.0e-45	174	COG0105	Nucleoside diphosphate kinase	135
641162115	481	29.02	273	457	53	244	1.0e-23	104	COG1651	Protein-disulfide isomerase	244
641162116	1025	19.65	240	688	9	403	7.0e-17	83.4	COG4262	Predicted spermidine synthase with an N-terminal membrane domain	508
641162118	510	40.62	11	387	12	371	1.0e-90	327	COG1488	Nicotinic acid phosphoribosyltransferase	405
641162119	229	40.56	7	145	6	144	7.0e-28	117	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
641162120	221	34.7	4	217	5	205	9.0e-30	123	COG1335	Nicotinamidase-related amidase	205
641162122	177	49.43	3	175	34	205	3.0e-48	184	COG1859	RNA:NAD 2'-phosphotransferase, TPT1/KptA family	211
641162125	198	41.51	40	195	45	203	2.0e-31	128	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
641162126	221	25.93	67	192	24	146	2.0e-07	49.5	COG1225	Peroxiredoxin	157
641162127	189	28.74	30	189	10	180	1.0e-21	96.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641162129	309	24.11	23	303	11	281	2.0e-14	73.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641162131	200	30.92	1	200	3	207	3.0e-30	125	COG0778	Nitroreductase	207
641162137	417	35.29	26	412	16	390	7.0e-68	251	COG3007	Trans-2-enoyl-CoA reductase	398
641162143	271	22.92	1	239	3	197	5.0e-14	71.9	COG0778	Nitroreductase	207
641162144	360	41.6	1	360	7	352	2.0e-79	289	COG3424	Predicted naringenin-chalcone synthase	356
641162145	181	32.75	8	175	1	168	7.0e-31	126	COG1755	Uncharacterized protein YpbQ, isoprenylcysteine carboxyl methyltransferase (ICMT) family	172
641162148	170	25.37	30	163	4	128	6.0e-12	63.9	COG4460	Uncharacterized protein	130
641162153	562	25.45	124	554	26	445	5.0e-48	185	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
641162161	185	28.34	5	184	15	196	2.0e-19	89.2	COG1515	Deoxyinosine 3'endonuclease (endonuclease V)	212
641162176	544	58.33	46	544	26	526	0.0e+00	650	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
641162179	184	24.38	36	182	2	153	1.0e-09	56.4	COG1225	Peroxiredoxin	157
641162180	613	42.78	21	595	1	566	0.0e+00	493	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
641162183	298	41.89	85	295	15	235	1.0e-37	150	COG0412	Dienelactone hydrolase	236
641162184	210	24.35	6	198	1	192	2.0e-08	52.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641162185	603	29.26	2	390	1	348	1.0e-58	221	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
641162186	579	21.47	375	559	26	208	4.0e-09	56.9	COG2755	Lysophospholipase L1 or related esterase	216
641162188	415	18.89	49	412	70	429	2.0e-07	51.1	COG4690	Dipeptidase	464
641162189	165	25.18	30	165	23	154	3.0e-07	48.2	COG4875	Uncharacterized protein	156
641162192	341	44.24	1	321	70	387	3.0e-87	315	COG3146	Predicted N-acyltransferase	387
641162193	113	48	8	107	8	107	8.0e-27	112	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
641162195	767	45.52	2	743	77	786	0.0e+00	759	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
641162196	519	23.51	7	255	1	263	3.0e-19	90.4	COG4219	Signal transducer regulating beta-lactamase production, contains  metallopeptidase domain	337
641162197	119	30.09	2	114	10	121	1.0e-12	65.7	COG3682	Predicted transcriptional regulator	123
641162199	513	48.89	2	498	1	459	0.0e+00	514	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641162201	503	54.27	1	503	2	493	0.0e+00	654	COG0554	Glycerol kinase	499
641162206	220	37.21	43	211	3	174	2.0e-25	109	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641162209	564	42.38	22	555	1	499	4.0e-114	405	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
641162213	167	41.42	2	165	1	167	6.0e-36	143	COG0262	Dihydrofolate reductase	167
641162214	1078	28.44	59	358	2	290	6.0e-36	146	COG0515	Serine/threonine protein kinase	384
641162218	135	29.01	1	131	6	125	3.0e-16	77.2	COG2346	Truncated hemoglobin YjbI	133
641162220	264	36.15	1	260	95	346	1.0e-48	186	COG0709	Selenophosphate synthase	346
641162221	116	45.19	6	109	3	106	2.0e-22	98.1	COG4551	Predicted protein tyrosine phosphatase	109
641162222	460	38.81	5	69	3	69	2.0e-13	70.7	COG3831	WGR domain, predicted DNA-binding domain in MolR	85
641162224	443	31.82	268	417	4	157	5.0e-20	92.4	COG4639	Predicted kinase	168
641162226	241	32.91	2	235	32	229	1.0e-33	136	COG0860	N-acetylmuramoyl-L-alanine amidase	231
641162234	1409	30.08	2	625	1	550	1.0e-111	399	COG0550	DNA topoisomerase IA	570
641162235	535	20.37	48	525	8	443	3.0e-14	74	COG1538	Outer membrane protein TolC	457
641162238	657	23.7	29	621	67	640	1.0e-36	148	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
641162239	300	27.03	6	298	2	291	4.0e-26	112	COG0583	DNA-binding transcriptional regulator, LysR family	297
641162241	188	23.16	1	173	8	184	2.0e-06	46.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641162242	331	22.81	4	320	26	367	3.0e-26	112	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
641162243	509	33.33	22	499	11	472	5.0e-88	318	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641162251	229	27.43	13	229	29	247	1.0e-20	93.5	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
641162252	678	46.33	2	674	20	689	0.0e+00	644	COG0480	Translation elongation factor EF-G, a GTPase	697
641162256	468	33.26	1	443	38	472	9.0e-87	314	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641162257	369	27.43	12	172	1	174	2.0e-08	53.9	COG2203	GAF domain	175
641162260	944	31.95	253	943	121	753	8.0e-88	318	COG1193	dsDNA-specific endonuclease/ATPase MutS2	753
641162262	117	29.21	28	116	4	88	7.0e-09	52.8	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
641162263	201	35.34	1	132	1	113	1.0e-17	83.4	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
641162264	229	46.05	4	79	9	83	6.0e-10	57.9	COG1563	Uncharacterized MnhB-related membrane protein	87
641162265	185	26.97	32	173	9	153	1.0e-11	63.1	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
641162266	129	33.04	8	122	6	115	5.0e-17	79.9	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
641162267	512	32.52	11	497	3	477	2.0e-61	230	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
641162268	533	28.83	29	523	5	479	5.0e-57	215	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
641162270	626	25.44	1	488	1	475	3.0e-48	187	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
641162273	1027	26.84	400	734	2	347	3.0e-42	168	COG0515	Serine/threonine protein kinase	384
641162275	630	27.01	72	619	2	464	8.0e-57	215	COG1109	Phosphomannomutase	464
641162278	459	43.93	7	431	1	405	9.0e-110	390	COG1252	NADH dehydrogenase, FAD-containing subunit	405
641162280	980	54.66	11	463	1	450	0.0e+00	569	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
641162280	980	61.89	475	948	15	496	0.0e+00	717	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
641162285	386	37.36	24	386	2	354	4.0e-80	292	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
641162286	497	25.57	5	298	1	306	1.0e-26	114	COG0515	Serine/threonine protein kinase	384
641162287	137	33.59	5	134	2	129	7.0e-20	89.7	COG3791	Uncharacterized conserved protein	133
641162290	448	23.21	118	446	14	333	6.0e-18	85.6	COG0642	Signal transduction histidine kinase	336
641162291	287	31.58	3	209	4	171	5.0e-14	71.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641162292	222	25.98	25	222	3	205	2.0e-17	82.7	COG0778	Nitroreductase	207
641162294	314	30.92	1	304	12	297	4.0e-46	178	COG3781	Predicted membrane chloride channel, bestrophin family	306
641162296	310	36.07	30	301	2	274	4.0e-32	132	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
641162297	181	34.07	1	181	19	195	6.0e-20	90.7	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
641162303	1874	25.77	2	275	17	304	6.0e-27	117	COG0515	Serine/threonine protein kinase	384
641162303	1874	26.48	281	1018	2	738	2.0e-59	226	COG3899	Predicted ATPase	849
641162307	703	36.32	64	703	11	654	0.0e+00	532	COG3590	Predicted metalloendopeptidase	654
641162308	263	44.05	8	258	3	247	3.0e-49	188	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641162310	452	31.97	153	440	80	365	1.0e-39	157	COG4585	Signal transduction histidine kinase	365
641162311	355	25.68	34	301	24	313	5.0e-27	115	COG0226	ABC-type phosphate transport system, periplasmic component	318
641162312	561	31.53	1	398	35	429	2.0e-59	223	COG1061	Superfamily II DNA or RNA helicase	442
641162314	323	20.43	5	312	46	365	6.0e-17	81.7	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
641162316	625	27.23	171	613	5	411	1.0e-37	151	COG2124	Cytochrome P450	411
641162321	370	52.82	3	354	2	352	6.0e-117	414	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
641162322	505	26.73	14	503	2	411	3.0e-52	199	COG2195	Di- or tripeptidase	414
641162324	309	47.5	137	296	10	162	4.0e-37	148	COG1045	Serine acetyltransferase	194
641162330	241	29.46	16	237	7	236	2.0e-26	112	COG1126	ABC-type polar amino acid transport system, ATPase component	240
641162336	361	27.19	27	357	4	314	4.0e-34	139	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641162337	1123	24.08	5	1103	1	1009	0.0e+00	491	COG0841	Multidrug efflux pump subunit AcrB	1009
641162338	124	42.22	8	97	9	98	5.0e-21	93.4	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
641162340	320	28.89	32	248	1	202	3.0e-16	79.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641162347	930	28.66	15	300	2	281	1.0e-35	145	COG0515	Serine/threonine protein kinase	384
641162351	286	25.32	49	272	41	253	7.0e-13	68	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
641162352	354	22.07	33	317	2	286	6.0e-10	58.8	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641162354	271	22.57	43	264	11	233	8.0e-13	67.8	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
641162355	507	31.12	2	507	1	482	3.0e-70	260	COG1233	Phytoene dehydrogenase-related protein	487
641162356	301	31.42	7	297	6	297	7.0e-32	131	COG0583	DNA-binding transcriptional regulator, LysR family	297
641162361	392	18.66	186	390	64	270	1.0e-08	54.3	COG0790	TPR repeat	292
641162362	400	46.73	4	397	2	395	2.0e-87	316	COG3214	Uncharacterized conserved protein YcaQ, contains winged helix DNA-binding domain	400
641162363	539	43.41	1	536	3	528	0.0e+00	549	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
641162364	325	32.6	26	242	1	211	2.0e-23	103	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641162368	499	28.47	77	353	2	296	7.0e-33	135	COG0515	Serine/threonine protein kinase	384
641162369	194	28.14	26	189	14	178	8.0e-06	43.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641162373	113	41.07	20	75	5	60	2.0e-08	51.4	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
641162394	383	30	99	369	66	365	2.0e-29	123	COG4188	Predicted dienelactone hydrolase	365
641162396	338	27.15	2	321	108	464	5.0e-27	115	COG5184	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	476
641162416	498	28.21	65	323	2	281	1.0e-34	141	COG0515	Serine/threonine protein kinase	384
641162420	392	24.66	72	348	3	285	1.0e-18	87.6	COG4974	Site-specific recombinase XerD	300
641162422	284	30.89	146	266	2	123	8.0e-14	71	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641162427	545	29.38	196	524	33	361	7.0e-31	129	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
641162428	414	25.63	35	411	47	443	5.0e-15	76	COG1538	Outer membrane protein TolC	457
641162433	236	30.47	2	232	35	250	3.0e-22	98.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641162439	272	21.49	18	255	8	246	4.0e-20	92.1	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
641162440	243	24.38	45	236	61	253	1.0e-08	53.7	COG0434	Predicted TIM-barrel enzyme	263
641162447	296	34.71	43	275	53	294	4.0e-45	175	COG3344	Retron-type reverse transcriptase	328
641162451	480	33.88	18	369	41	399	2.0e-69	256	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
641162452	217	31.46	1	213	1	209	2.0e-31	129	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
641162455	381	20.95	1	344	6	340	9.0e-09	55.1	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
641162457	404	54.76	2	387	14	400	7.0e-113	400	COG3844	Kynureninase	407
641162461	474	29.13	13	443	1	404	5.0e-54	205	COG2124	Cytochrome P450	411
641162464	450	24.21	204	388	19	203	3.0e-18	86.5	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
641162467	230	28.41	1	175	9	184	9.0e-20	90.4	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
641162468	284	28.17	1	276	1	244	6.0e-37	148	COG0121	Predicted glutamine amidotransferase	252
641162471	244	29.44	23	234	29	230	9.0e-31	127	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
641162479	236	47.64	2	234	3	220	4.0e-60	224	COG0283	Cytidylate kinase	222
641162480	567	49.46	10	563	1	540	0.0e+00	503	COG0539	Ribosomal protein S1	541
641162481	167	59.87	8	159	1	152	4.0e-44	170	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
641162482	169	29.38	7	165	6	151	3.0e-16	78.1	COG0781	Transcription termination factor NusB	151
641162485	795	34.67	7	756	13	709	0.0e+00	514	COG0643	Chemotaxis protein histidine kinase CheA	716
641162486	191	31.21	39	179	18	158	1.0e-26	113	COG0835	Chemotaxis signal transduction protein	165
641162487	176	37.25	17	169	7	152	9.0e-24	103	COG0835	Chemotaxis signal transduction protein	165
641162490	280	36.9	3	270	1	265	3.0e-64	239	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
641162491	361	40.06	2	361	5	349	3.0e-75	276	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
641162494	302	49.83	4	302	2	300	8.0e-94	337	COG4974	Site-specific recombinase XerD	300
641162495	227	29.33	24	227	21	221	1.0e-09	56.6	COG1994	Zn-dependent protease (includes SpoIVFB)	230
641162496	495	36.29	52	295	2	239	1.0e-38	155	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
641162497	517	43.27	120	289	8	178	4.0e-29	123	COG1386	Chromosome segregation and condensation protein ScpB	184
641162498	300	47.22	29	273	1	248	2.0e-62	232	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
641162499	118	49.18	58	118	1	61	5.0e-14	69.9	COG0199	Ribosomal protein S14	61
641162500	84	37.65	1	84	1	74	3.0e-18	83.4	COG0254	Ribosomal protein L31	75
641162501	470	40.22	10	466	3	453	4.0e-101	362	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
641162502	461	35.01	17	460	2	454	1.0e-73	271	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
641162503	291	27.92	6	281	3	276	6.0e-36	144	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
641162509	426	56.73	11	425	6	413	0.0e+00	580	COG0112	Glycine/serine hydroxymethyltransferase	413
641162512	787	22.66	502	787	33	354	9.0e-10	59.6	COG1858	Cytochrome c peroxidase	364
641162514	528	39.69	7	520	1	462	3.0e-113	402	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
641162515	227	54.87	33	226	1	189	3.0e-71	261	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
641162517	357	48.3	6	357	2	338	2.0e-88	319	COG0547	Anthranilate phosphoribosyltransferase	338
641162518	264	49.22	8	263	1	254	6.0e-69	253	COG0134	Indole-3-glycerol phosphate synthase	254
641162519	237	33.94	9	223	1	204	3.0e-34	138	COG0135	Phosphoribosylanthranilate isomerase	208
641162520	428	63.68	19	408	7	396	0.0e+00	631	COG0133	Tryptophan synthase beta chain	396
641162521	287	44.77	16	286	1	265	4.0e-65	241	COG0159	Tryptophan synthase alpha chain	265
641162526	442	18.45	2	333	9	303	3.0e-11	63.6	COG0644	Dehydrogenase (flavoprotein)	396
641162527	455	16.56	39	437	28	483	2.0e-33	136	COG3202	ATP/ADP translocase	509
641162528	340	22.54	1	255	1	277	1.0e-20	94.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641162531	270	33.05	22	254	8	233	4.0e-31	128	COG1183	Phosphatidylserine synthase	234
641162536	217	20	9	216	31	235	2.0e-10	59.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
641162537	288	37.85	3	284	2	282	5.0e-52	198	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
641162543	221	34.88	5	216	17	226	2.0e-41	162	COG2949	Uncharacterized periplasmic protein SanA, affects membrane permeability for vancomycin	235
641162544	354	25.82	6	319	27	359	1.0e-30	127	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
641162549	244	21.97	1	221	2	169	1.0e-06	46.9	COG0622	Predicted phosphodiesterase	172
641162558	888	27.05	56	324	2	281	1.0e-31	132	COG0515	Serine/threonine protein kinase	384
641162560	207	34.86	5	176	1	175	6.0e-21	94.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641162564	1978	22.3	345	1978	129	1619	4.0e-101	364	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
641162566	254	33.47	7	248	11	251	4.0e-41	161	COG0631	Serine/threonine protein phosphatase PrpC	262
641162567	416	22.38	102	367	19	304	3.0e-19	90.2	COG0515	Serine/threonine protein kinase	384
641162569	571	54.85	5	571	1	554	0.0e+00	733	COG2759	Formyltetrahydrofolate synthetase	554
641162574	297	25.27	27	295	4	278	2.0e-15	77	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641162576	767	30.48	498	763	24	282	2.0e-20	94.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641162577	327	26.24	10	282	1	269	2.0e-17	83.5	COG3386	Sugar lactone lactonase YvrE	307
641162578	331	39.07	47	324	47	312	1.0e-39	157	COG0657	Acetyl esterase/lipase	312
641162582	537	40.27	16	536	2	462	0.0e+00	481	COG0215	Cysteinyl-tRNA synthetase	464
641162590	721	32	14	633	2	564	4.0e-102	366	COG0323	DNA mismatch repair ATPase MutL	638
641162591	319	40.27	2	285	7	282	2.0e-63	236	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
641162592	327	64.08	7	315	5	313	2.0e-123	435	COG0825	Acetyl-CoA carboxylase alpha subunit	317
641162593	770	22.94	345	575	16	228	9.0e-10	59.4	COG0705	Membrane associated serine protease, rhomboid family	228
641162595	101	46.74	9	100	6	96	4.0e-25	106	COG2154	Pterin-4a-carbinolamine dehydratase	101
641162596	696	37.36	247	427	3	181	4.0e-29	123	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
641162596	696	50.59	439	693	2	252	4.0e-79	289	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
641162598	285	27.67	31	263	57	308	2.0e-17	83.4	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
641162600	215	33.18	9	215	16	217	9.0e-36	143	COG0321	Lipoate-protein ligase B	221
641162603	622	24	13	246	2	273	2.0e-17	84.8	COG0515	Serine/threonine protein kinase	384
641162604	1781	32.67	1562	1774	48	298	3.0e-33	138	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641162604	1781	35.6	922	1334	57	466	3.0e-59	225	COG2319	WD40 repeat	466
641162605	290	32.22	86	263	3	181	7.0e-19	87.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641162606	933	30.03	58	326	1	280	5.0e-36	146	COG0515	Serine/threonine protein kinase	384
641162610	455	29.97	22	375	4	347	9.0e-43	168	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
641162613	217	22.16	40	197	12	178	3.0e-11	62	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641162617	175	27.93	31	140	1	111	6.0e-13	67.3	COG3597	Uncharacterized conserved protein, DUF697 family	139
641162625	568	28.52	12	542	12	526	8.0e-86	311	COG4615	ABC-type siderophore export system, fused ATPase and permease components	546
641162628	376	19.08	35	328	3	279	1.0e-10	61.3	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
641162630	206	20.57	42	181	1	137	3.0e-10	58.5	COG3597	Uncharacterized conserved protein, DUF697 family	139
641162633	799	23.48	94	430	43	397	2.0e-10	62	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
641162634	914	28.85	39	321	1	281	4.0e-35	143	COG0515	Serine/threonine protein kinase	384
641162635	139	36.64	6	136	6	131	2.0e-19	88.4	COG3788	Uncharacterized membrane protein YecN, MAPEG domain	131
641162638	547	26.6	38	335	3	282	9.0e-34	138	COG0515	Serine/threonine protein kinase	384
641162639	696	48.83	9	691	20	683	0.0e+00	740	COG0339	Zn-dependent oligopeptidase	683
641162640	259	36.4	9	258	3	241	2.0e-52	199	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
641162643	590	25.77	205	568	46	425	2.0e-26	114	COG5184	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	476
641162644	350	22.35	46	273	12	254	2.0e-07	50.4	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
641162649	188	32.28	2	188	8	181	1.0e-30	126	COG3703	Cation transport regulator ChaC	190
641162653	413	29.39	16	319	3	306	1.0e-34	141	COG0515	Serine/threonine protein kinase	384
641162654	268	20.9	29	265	4	261	2.0e-12	66.3	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
641162655	374	60.16	1	373	1	370	0.0e+00	495	COG0686	Alanine dehydrogenase	371
641162659	588	21.01	14	334	16	335	6.0e-13	69.4	COG4402	Uncharacterized protein	457
641162662	376	20.42	74	345	18	270	4.0e-13	69.7	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
641162664	396	29.62	39	359	25	362	4.0e-25	109	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
641162666	1085	27.83	21	1046	2	1009	0.0e+00	601	COG0841	Multidrug efflux pump subunit AcrB	1009
641162670	134	53.15	25	134	1	110	7.0e-29	119	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
641162673	319	28.52	77	315	23	304	5.0e-22	98.9	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
641162678	375	30.96	32	373	20	395	6.0e-57	214	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
641162679	221	33.65	3	208	7	210	2.0e-28	119	COG0811	Biopolymer transport protein ExbB/TolQ	216
641162680	149	29.29	7	146	8	137	2.0e-15	75.3	COG0848	Biopolymer transport protein ExbD	137
641162681	310	21.77	64	309	15	244	1.0e-07	50.9	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
641162682	909	15.26	266	877	76	737	5.0e-12	67.3	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
641162685	683	37.83	336	638	22	317	4.0e-55	209	COG0616	Periplasmic serine protease, ClpP class	317
641162690	485	30.6	1	480	13	457	4.0e-46	179	COG0471	Di- and tricarboxylate transporter	461
641162691	562	34.67	9	550	4	537	4.0e-115	408	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
641162693	290	28.97	37	280	85	324	1.0e-25	110	COG0642	Signal transduction histidine kinase	336
641162694	373	25.4	2	373	4	314	9.0e-28	118	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641162696	519	40.69	62	407	39	386	7.0e-90	324	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
641162697	326	31.63	1	308	2	310	3.0e-45	176	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
641162698	181	30.57	25	180	3	147	5.0e-22	97.6	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
641162699	433	36.89	5	429	3	412	1.0e-85	310	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
641162700	251	38.96	4	247	9	250	4.0e-43	168	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641162701	420	30.49	10	418	1	375	2.0e-71	263	COG3425	3-hydroxy-3-methylglutaryl CoA synthase	377
641162702	252	30.53	12	235	28	252	1.0e-28	120	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641162703	271	29.71	28	261	12	249	8.0e-31	127	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641162704	570	25.9	307	552	2	250	4.0e-23	103	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641162706	366	59.36	1	366	1	372	0.0e+00	467	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
641162710	194	49.48	1	194	2	193	4.0e-53	200	COG0807	GTP cyclohydrolase II	193
641162712	331	44.89	5	322	7	313	3.0e-86	312	COG0275	16S rRNA C1402 N4-methylase RsmH	314
641162714	767	33.72	102	668	11	597	3.0e-107	383	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
641162718	128	48.35	1	91	2	92	2.0e-26	111	COG0776	Bacterial nucleoid DNA-binding protein	94
641162722	557	41	23	557	7	488	0.0e+00	484	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
641162726	485	20.73	133	456	45	398	2.0e-10	60.7	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
641162727	194	38.62	1	183	3	190	4.0e-54	204	COG1435	Thymidine kinase	201
641162732	99	36.63	1	99	3	99	3.0e-13	66.9	COG0607	Rhodanese-related sulfurtransferase	110
641162733	564	45.9	5	545	1	530	0.0e+00	545	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
641162734	676	40.58	25	670	6	639	0.0e+00	589	COG1166	Arginine decarboxylase (spermidine biosynthesis)	652
641162738	1939	27.54	1461	1799	25	336	3.0e-28	122	COG0642	Signal transduction histidine kinase	336
641162738	1939	29.98	299	1172	2	848	2.0e-113	405	COG3899	Predicted ATPase	849
641162741	204	32.76	6	178	4	177	2.0e-19	89.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641162742	951	29.43	38	317	2	285	3.0e-42	168	COG0515	Serine/threonine protein kinase	384
641162748	1021	24.78	112	885	41	735	2.0e-65	244	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
641162749	573	25.96	274	550	14	289	1.0e-22	101	COG3301	Formate-dependent nitrite reductase, membrane component NrfD	305
641162749	573	44.81	1	177	9	191	1.0e-56	214	COG0437	Fe-S-cluster-containing dehydrogenase component	203
641162750	565	31.24	2	523	32	540	5.0e-81	295	COG0659	Sulfate permease or related transporter, MFS superfamily	554
641162753	318	34.29	44	318	51	324	3.0e-52	199	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
641162756	310	34.82	23	266	2	241	4.0e-40	158	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
641162759	567	34.05	67	527	56	516	8.0e-100	358	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
641162760	212	37.89	24	211	24	207	6.0e-28	117	COG4339	Predicted metal-dependent phosphohydrolase, HD superfamily	208
641162761	286	25.55	5	285	10	306	7.0e-15	74.9	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
641162765	192	29.57	3	186	1	181	3.0e-10	58.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641162769	405	27.71	62	395	41	358	5.0e-38	152	COG1858	Cytochrome c peroxidase	364
641162770	140	29.73	2	131	11	155	2.0e-09	55	COG4639	Predicted kinase	168
641162771	274	33.65	18	211	12	212	3.0e-20	92.8	COG4021	tRNA(His) 5'-end guanylyltransferase	249
641162773	467	22.3	30	466	1	420	4.0e-33	136	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
641162774	438	34.91	1	422	10	423	9.0e-97	347	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
641162775	338	44.24	9	335	11	334	9.0e-88	317	COG4266	Allantoicase	334
641162776	174	31.97	31	174	30	172	1.0e-08	53	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
641162777	114	49.12	6	114	11	124	2.0e-31	127	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
641162781	227	25.51	22	217	12	201	6.0e-07	48.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641162782	302	34.85	36	296	16	273	3.0e-44	172	COG3687	Predicted metal-dependent hydrolase	280
641162790	558	44.75	49	557	3	493	0.0e+00	523	COG3517	Predicted component of the type VI protein secretion system	495
641162791	168	36.6	8	154	12	162	5.0e-25	107	COG3516	Predicted component of the type VI protein secretion system	169
641162792	314	27.06	1	164	5	173	6.0e-10	58.6	COG3913	Uncharacterized protein	227
641162793	1212	27.36	1	1160	15	1160	0.0e+00	534	COG3523	Type VI protein secretion system component VasK	1188
641162794	261	27.62	18	222	53	262	3.0e-25	108	COG3455	Type VI protein secretion system component VasF	262
641162795	453	30.02	6	433	3	431	3.0e-73	269	COG3522	Predicted component of the type VI protein secretion system	446
641162796	227	26.03	21	166	1	139	1.0e-14	73.8	COG3521	Predicted component of the type VI protein secretion system	159
641162814	145	36.89	45	145	4	102	5.0e-14	70.3	COG0607	Rhodanese-related sulfurtransferase	110
641162815	143	41.84	1	141	3	139	5.0e-36	143	COG1832	Predicted CoA-binding protein	140
641162827	1515	22.72	866	1272	26	440	1.0e-12	70.2	COG2319	WD40 repeat	466
641162829	820	28.52	61	341	2	285	2.0e-31	131	COG0515	Serine/threonine protein kinase	384
641162831	206	33.71	3	172	1	175	1.0e-16	79.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641162833	206	25.64	49	197	43	194	4.0e-07	48.5	COG3145	Alkylated DNA repair dioxygenase AlkB	194
641162836	439	21.83	5	383	3	360	1.0e-11	64.4	COG0644	Dehydrogenase (flavoprotein)	396
641162839	323	27.19	97	317	31	250	3.0e-28	119	COG3591	V8-like Glu-specific endopeptidase	251
641162841	360	22.3	9	296	18	275	4.0e-28	119	COG0682	Prolipoprotein diacylglyceryltransferase	287
641162844	453	25.9	149	453	24	314	8.0e-27	115	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641162848	182	29.38	9	181	8	181	7.0e-18	84	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641162856	601	36.12	2	601	14	613	0.0e+00	488	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
641162857	1342	30.07	54	329	1	274	4.0e-37	151	COG0515	Serine/threonine protein kinase	384
641162858	396	20.3	1	383	3	376	2.0e-19	90.4	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
641162859	412	35.34	295	410	2	117	1.0e-15	77.8	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641162862	400	26.56	23	327	1	288	9.0e-34	137	COG0515	Serine/threonine protein kinase	384
641162863	534	18.4	9	476	1	430	7.0e-21	95.6	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
641162864	332	23.62	29	286	27	285	2.0e-12	67.4	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
641162867	325	47.39	14	316	4	294	1.0e-68	253	COG2040	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)	300
641162868	277	22.18	36	271	28	236	2.0e-13	70	COG0412	Dienelactone hydrolase	236
641162869	397	29.11	6	285	3	310	5.0e-35	142	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
641162879	466	29.86	202	462	58	335	1.0e-22	101	COG1075	Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold	336
641162880	156	25.85	1	145	13	149	5.0e-09	53.9	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
641162881	747	23.07	6	732	39	765	4.0e-73	269	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
641162884	529	26.21	6	517	2	466	5.0e-58	219	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641162886	797	22.68	157	768	23	563	3.0e-39	157	COG2936	Predicted acyl esterase	563
641162888	191	27.96	14	189	16	199	7.0e-18	83.8	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
641162889	643	33.85	193	642	1	422	4.0e-86	312	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
641162893	1099	25.45	44	349	2	290	3.0e-31	131	COG0515	Serine/threonine protein kinase	384
641162895	590	39.97	1	573	3	558	1.0e-93	337	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
641162896	639	33.46	83	619	5	537	1.0e-103	370	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
641162901	137	35.2	7	131	8	132	6.0e-22	96.5	COG0824	Acyl-CoA thioesterase FadM	137
641162903	438	28.67	22	274	2	284	3.0e-31	129	COG0515	Serine/threonine protein kinase	384
641162906	780	20.94	17	679	3	570	2.0e-25	111	COG2766	Predicted Ser/Thr protein kinase	649
641162907	453	46.24	1	447	4	450	1.0e-118	420	COG1115	Na+/alanine symporter	452
641162909	543	32.21	106	541	33	467	8.0e-62	231	COG2027	D-alanyl-D-alanine carboxypeptidase	470
641162912	255	41.28	38	251	18	227	8.0e-31	127	COG0670	Integral membrane protein, interacts with FtsH	233
641162915	768	23.12	431	744	8	347	6.0e-26	113	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
641162916	664	22.56	29	299	25	319	1.0e-23	105	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
641162917	587	23.38	37	338	19	336	4.0e-24	107	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
641162918	1178	36.76	354	888	2	552	2.0e-112	401	COG2192	Predicted carbamoyl transferase, NodU family	555
641162920	109	34.38	5	100	3	89	4.0e-10	56.8	COG3326	Uncharacterized membrane protein YsdA, DUF1294 family	94
641162928	530	28.29	2	504	8	487	6.0e-45	175	COG1233	Phytoene dehydrogenase-related protein	487
641162931	348	37.14	32	205	17	177	7.0e-20	91.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641162933	461	35.61	9	422	3	400	5.0e-85	308	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
641162935	416	23.08	67	309	19	264	3.0e-17	83.2	COG1589	Cell division septal protein FtsQ	269
641162936	420	45.39	1	420	7	418	6.0e-111	394	COG0849	Cell division ATPase FtsA	418
641162940	353	34.24	66	320	45	276	5.0e-42	165	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
641162942	889	27.55	141	864	75	753	6.0e-98	352	COG1882	Pyruvate-formate lyase	755
641162948	176	61.29	9	163	4	158	3.0e-59	221	COG0669	Phosphopantetheine adenylyltransferase	159
641162951	604	25.88	26	573	6	532	3.0e-60	226	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641162952	375	26.56	9	371	33	410	5.0e-33	135	COG5379	S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase	414
641162955	759	27.49	1	265	3	277	1.0e-34	142	COG0515	Serine/threonine protein kinase	384
641162962	464	29.98	15	454	3	410	6.0e-56	211	COG2124	Cytochrome P450	411
641162974	222	23.08	25	219	2	169	6.0e-16	77.7	COG0622	Predicted phosphodiesterase	172
641162977	1041	21.63	695	976	31	235	1.0e-06	49.6	COG3063	Tfp pilus assembly protein PilF	250
641162978	234	54.08	1	233	7	236	2.0e-77	282	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
641162979	343	41.96	7	334	3	324	6.0e-55	208	COG3380	Predicted NAD/FAD-dependent oxidoreductase	331
641162980	181	28.79	42	159	5	135	1.0e-13	69.5	COG1225	Peroxiredoxin	157
641162987	253	25.54	18	182	43	223	3.0e-14	72.6	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
641162993	706	21.24	6	706	6	608	8.0e-29	122	COG4206	Outer membrane cobalamin receptor protein	608
641163002	591	39.52	98	586	1	483	2.0e-98	353	COG0286	Type I restriction-modification system, DNA methylase subunit	489
641163003	511	36.73	8	470	2	461	5.0e-92	331	COG0286	Type I restriction-modification system, DNA methylase subunit	489
641163004	403	19.6	8	358	1	345	3.0e-17	83.6	COG0732	Restriction endonuclease S subunit	391
641163012	185	27.71	20	182	18	181	7.0e-08	50.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641163016	421	31.4	141	371	61	283	9.0e-21	94.9	COG4974	Site-specific recombinase XerD	300
641163020	506	22.66	53	365	74	420	1.0e-18	88.4	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
641163021	528	29.58	170	524	120	454	3.0e-48	187	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641163040	459	26.8	74	333	2	289	9.0e-33	134	COG0515	Serine/threonine protein kinase	384
641163041	186	23.16	15	186	5	181	1.0e-09	56.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641163046	369	33.86	124	358	48	287	4.0e-29	122	COG4974	Site-specific recombinase XerD	300
641163053	227	28.31	30	191	31	192	1.0e-14	73	COG3382	B3/B4 domain (DNA/RNA-binding domain of Phe-tRNA-synthetase)	229
641163056	110	37.78	22	110	9	98	2.0e-11	61	COG0640	DNA-binding transcriptional regulator, ArsR family	110
641163057	343	47.2	1	338	9	337	1.0e-78	286	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
641163059	268	24.51	36	263	30	280	1.0e-06	47.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641163060	395	29.33	40	302	2	277	3.0e-42	166	COG0515	Serine/threonine protein kinase	384
641163063	567	70.7	103	530	2	430	0.0e+00	748	COG0422	Thiamine biosynthesis protein ThiC	432
641163066	409	18.69	56	384	55	375	1.0e-06	48.4	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
641163068	1100	21.3	1	978	33	1114	1.0e-76	282	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
641163073	1971	24.18	309	1128	2	748	5.0e-53	204	COG3899	Predicted ATPase	849
641163073	1971	27.86	9	270	1	277	2.0e-35	146	COG0515	Serine/threonine protein kinase	384
641163073	1971	29.52	1701	1971	85	334	4.0e-31	131	COG0642	Signal transduction histidine kinase	336
641163074	1263	41.74	9	697	1	674	0.0e+00	546	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
641163074	1263	49.73	717	1255	3	531	0.0e+00	600	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
641163076	172	28.15	1	135	2	134	3.0e-15	75.1	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
641163077	290	28.86	1	290	2	295	1.0e-23	104	COG0583	DNA-binding transcriptional regulator, LysR family	297
641163081	240	37.33	10	228	20	243	3.0e-40	158	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
641163082	397	29.09	122	379	10	274	3.0e-24	106	COG3386	Sugar lactone lactonase YvrE	307
641163086	612	41.27	107	481	5	378	2.0e-94	340	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
641163088	341	30.58	13	339	5	325	7.0e-60	224	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
641163092	1049	28.1	72	358	2	288	5.0e-35	143	COG0515	Serine/threonine protein kinase	384
641163093	344	25.08	9	334	14	334	3.0e-26	112	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
641163094	445	36.61	2	444	13	454	1.0e-96	347	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
641163095	316	16.89	67	284	4	212	5.0e-06	45.6	COG0671	Membrane-associated phospholipid phosphatase	232
641163107	878	28.53	77	412	42	362	7.0e-45	176	COG4289	Uncharacterized protein	458
641163110	630	24.8	59	410	2	361	2.0e-34	141	COG0515	Serine/threonine protein kinase	384
641163111	305	27.24	6	305	1	295	1.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
641163112	1888	25.13	293	1054	2	741	2.0e-69	259	COG3899	Predicted ATPase	849
641163115	394	44.08	4	394	1	391	4.0e-108	385	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
641163116	435	33.94	30	243	51	268	1.0e-10	61.5	COG0457	Tetratricopeptide (TPR) repeat	291
641163119	286	37.41	9	282	1	279	1.0e-42	166	COG0515	Serine/threonine protein kinase	384
641163123	289	40.62	34	286	1	227	2.0e-52	199	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641163124	503	34.03	175	499	3	328	2.0e-36	147	COG0642	Signal transduction histidine kinase	336
641163132	1003	25.3	57	372	2	285	8.0e-31	129	COG0515	Serine/threonine protein kinase	384
641163135	253	28.46	5	244	2	227	3.0e-20	92.3	COG1011	FMN phosphatase YigB, HAD superfamily	229
641163137	471	26.93	43	458	10	411	3.0e-64	239	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
641163141	125	61.34	4	122	6	124	5.0e-42	162	COG3651	Uncharacterized conserved protein, DUF2237 family	125
641163142	207	30.13	1	207	2	228	3.0e-21	95	COG1011	FMN phosphatase YigB, HAD superfamily	229
641163143	580	33.16	6	397	4	337	3.0e-54	206	COG2187	Aminoglycoside phosphotransferase family enzyme	337
641163143	580	35.33	401	567	3	166	2.0e-20	94.6	COG0645	Predicted kinase	170
641163144	1147	23.53	33	338	2	302	2.0e-31	131	COG0515	Serine/threonine protein kinase	384
641163145	527	26.49	43	393	2	365	2.0e-44	173	COG0515	Serine/threonine protein kinase	384
641163146	276	26.94	23	274	9	256	2.0e-14	72.7	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
641163151	446	33.33	1	67	1	69	2.0e-13	70.7	COG3831	WGR domain, predicted DNA-binding domain in MolR	85
641163153	286	27.12	1	286	1	295	2.0e-20	93.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
641163160	589	34.84	285	588	14	321	2.0e-50	193	COG0142	Geranylgeranyl pyrophosphate synthase	322
641163162	317	37.41	50	310	6	254	1.0e-35	143	COG0584	Glycerophosphoryl diester phosphodiesterase	257
641163169	241	42.37	5	240	7	237	2.0e-64	238	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
641163170	293	32.86	17	291	3	276	7.0e-38	151	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
641163175	758	30.69	70	753	2	647	4.0e-96	346	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
641163177	351	37.64	1	351	1	335	1.0e-65	243	COG3938	Proline racemase	341
641163181	199	27.78	7	113	1	107	4.0e-07	48.5	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
641163182	346	37.87	5	331	1	326	2.0e-66	246	COG3938	Proline racemase	341
641163187	225	27.62	20	225	11	198	2.0e-23	103	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
641163188	148	39.86	18	148	21	163	3.0e-31	127	COG1791	Acireductone dioxygenase (methionine salvage), cupin superfamily	181
641163189	440	60.52	11	432	4	420	0.0e+00	624	COG0499	S-adenosylhomocysteine hydrolase	420
641163191	220	34.07	3	180	1	182	8.0e-20	90.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641163193	1238	32.99	820	1192	60	446	4.0e-42	167	COG2319	WD40 repeat	466
641163194	266	28.68	8	257	6	263	2.0e-23	102	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
641163197	356	35.76	30	340	1	289	4.0e-55	208	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
641163198	205	30.24	3	199	1	202	2.0e-21	95.7	COG1335	Nicotinamidase-related amidase	205
641163199	182	23.95	1	167	26	192	7.0e-07	47.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641163202	271	34.52	180	260	19	102	1.0e-08	53.8	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
641163205	507	26.57	23	420	2	367	2.0e-30	127	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
641163206	658	21.72	131	555	11	422	5.0e-10	60	COG1657	Squalene cyclase	517
641163212	155	47.37	1	152	1	151	5.0e-35	140	COG0782	Transcription elongation factor, GreA/GreB family	151
641163213	282	38.65	13	262	3	247	8.0e-51	193	COG2820	Uridine phosphorylase	248
641163218	169	36.48	10	167	5	139	4.0e-27	114	COG0394	Protein-tyrosine-phosphatase	139
641163220	891	41.98	13	673	1	569	0.0e+00	554	COG0550	DNA topoisomerase IA	570
641163226	378	39.89	17	376	12	342	1.0e-85	309	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
641163227	471	52.88	1	466	2	457	0.0e+00	540	COG0773	UDP-N-acetylmuramate-alanine ligase	459
641163228	325	43.39	30	323	1	288	4.0e-75	275	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
641163230	81	31.82	7	72	3	65	4.0e-06	43	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
641163233	421	32.17	7	254	16	271	1.0e-25	111	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
641163239	547	49.09	232	546	14	342	1.0e-82	301	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
641163243	326	22.92	106	326	82	312	2.0e-11	63.6	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641163246	1091	63.66	13	411	1	397	0.0e+00	521	COG0458	Carbamoylphosphate synthase large subunit	400
641163252	562	37.3	42	351	2	297	1.0e-78	287	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
641163252	562	39.78	366	546	1	176	5.0e-55	209	COG1838	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain	184
641163256	468	24.09	200	467	77	336	5.0e-24	106	COG0642	Signal transduction histidine kinase	336
641163257	184	51.72	3	176	9	181	1.0e-46	179	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
641163259	399	42.75	1	392	2	383	1.0e-101	363	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
641163260	367	42.78	1	363	4	352	4.0e-103	368	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
641163262	244	41.6	7	243	6	230	1.0e-47	183	COG0571	dsRNA-specific ribonuclease	235
641163263	301	28.57	7	298	1	290	2.0e-22	100	COG0583	DNA-binding transcriptional regulator, LysR family	297
641163266	930	27.05	327	891	11	560	5.0e-59	223	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
641163267	397	26.87	20	313	15	273	4.0e-20	92.7	COG1566	Multidrug resistance efflux pump	352
641163269	445	29.21	2	354	7	343	2.0e-46	180	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
641163272	362	36.73	40	254	21	243	6.0e-35	141	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
641163273	651	56.3	9	613	1	596	0.0e+00	702	COG0465	ATP-dependent Zn proteases	596
641163274	239	30.35	14	209	12	207	8.0e-20	90.8	COG3762	Uncharacterized membrane protein	213
641163277	168	28.67	32	167	9	155	2.0e-12	65.3	COG1225	Peroxiredoxin	157
641163278	189	38.92	10	176	16	177	2.0e-28	118	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641163279	712	25.45	141	401	32	300	9.0e-08	52.6	COG1413	HEAT repeat	335
641163284	930	42.75	1	923	10	843	0.0e+00	794	COG0249	DNA mismatch repair ATPase MutS	843
641163286	169	55.77	5	160	1	150	1.0e-52	198	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
641163292	799	36.59	2	771	8	743	0.0e+00	573	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
641163299	1463	26.21	12	389	2	376	1.0e-40	163	COG0515	Serine/threonine protein kinase	384
641163300	668	39.32	1	557	1	528	0.0e+00	465	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
641163301	776	30.07	353	640	49	336	2.0e-29	125	COG0642	Signal transduction histidine kinase	336
641163308	414	24.7	16	331	1	320	1.0e-30	127	COG0714	MoxR-like ATPase	329
641163311	820	28.49	302	475	8	154	3.0e-23	103	COG0437	Fe-S-cluster-containing dehydrogenase component	203
641163314	418	30.97	59	348	1	305	3.0e-40	159	COG0515	Serine/threonine protein kinase	384
641163333	129	54.62	1	129	1	129	2.0e-34	138	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
641163334	1160	61.03	12	1155	6	1148	0.0e+00	1663	COG1038	Pyruvate carboxylase	1149
641163339	267	39.85	3	267	1	243	9.0e-37	147	COG3279	DNA-binding response regulator, LytR/AlgR family	244
641163342	371	20.8	11	371	2	359	4.0e-14	72.7	COG3489	Predicted periplasmic lipoprotein	359
641163343	463	52.18	20	463	29	481	0.0e+00	489	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
641163344	375	44.69	5	371	29	428	9.0e-81	294	COG3487	Uncharacterized iron-regulated protein	446
641163345	243	26.2	1	229	13	282	2.0e-23	102	COG0515	Serine/threonine protein kinase	384
641163346	304	32.95	14	271	18	281	6.0e-48	184	COG1398	Fatty-acid desaturase	289
641163347	230	44.16	1	230	4	228	5.0e-55	207	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641163348	1083	30.19	38	326	2	277	4.0e-35	144	COG0515	Serine/threonine protein kinase	384
641163352	333	27.43	2	332	59	385	6.0e-30	125	COG1680	CubicO group peptidase, beta-lactamase class C family	390
641163353	198	23.39	16	184	12	154	8.0e-11	60.3	COG1225	Peroxiredoxin	157
641163355	330	23.4	1	308	1	322	6.0e-16	78.6	COG5351	Uncharacterized protein	367
641163357	401	22.19	17	389	6	329	1.0e-06	47.7	COG5351	Uncharacterized protein	367
641163359	365	26.39	54	319	3	282	7.0e-27	115	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641163361	515	22.56	75	437	74	407	9.0e-32	131	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
641163363	382	41.24	3	382	1	388	1.0e-74	273	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641163364	497	30.21	1	493	7	522	1.0e-72	267	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641163365	251	20.97	14	247	17	282	2.0e-10	59.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641163367	458	30.49	107	405	2	282	3.0e-35	143	COG0515	Serine/threonine protein kinase	384
641163370	559	31.4	234	558	106	393	1.0e-40	161	COG2385	Peptidoglycan hydrolase (amidase) enhancer domain	397
641163372	305	31.51	1	305	7	304	1.0e-41	163	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
641163373	308	35.92	17	300	36	304	2.0e-38	153	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
641163374	651	19.33	8	565	3	493	6.0e-26	113	COG0591	Na+/proline symporter	493
641163379	262	50.38	1	262	1	262	3.0e-77	281	COG0300	Short-chain dehydrogenase	265
641163380	950	28.05	41	319	2	281	5.0e-33	137	COG0515	Serine/threonine protein kinase	384
641163381	262	36.36	25	252	9	234	1.0e-33	136	COG4798	Predicted methyltransferase	238
641163382	917	24.92	53	329	2	281	2.0e-34	141	COG0515	Serine/threonine protein kinase	384
641163386	405	23.67	2	388	17	413	2.0e-11	63.5	COG4102	Uncharacterized conserved protein, DUF1501 family	418
641163389	494	24.8	15	491	3	455	4.0e-23	103	COG0277	FAD/FMN-containing dehydrogenase	459
641163393	389	29.95	205	384	13	198	8.0e-16	78.3	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
641163397	341	27.6	86	277	46	220	1.0e-09	57.7	COG2801	Transposase InsO and inactivated derivatives	232
641163400	413	21.68	9	368	3	303	2.0e-09	56.8	COG3547	Transposase	303
641163402	388	29.45	1	245	8	279	4.0e-31	129	COG0515	Serine/threonine protein kinase	384
641163405	427	39.95	2	381	95	470	8.0e-88	317	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641163407	341	27.6	86	277	46	220	1.0e-09	57.7	COG2801	Transposase InsO and inactivated derivatives	232
641163411	472	29.03	87	334	2	277	4.0e-28	119	COG0515	Serine/threonine protein kinase	384
641163412	175	27.93	1	174	1	179	6.0e-11	60.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641163417	401	28.45	137	353	64	283	2.0e-21	96.8	COG4974	Site-specific recombinase XerD	300
641163421	118	39.39	16	81	5	68	2.0e-06	44.8	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
641163429	391	54.8	7	391	1	395	0.0e+00	506	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
641163430	468	48.21	10	315	3	300	2.0e-104	372	COG0031	Cysteine synthase	300
641163431	1051	25.76	63	336	2	277	2.0e-31	132	COG0515	Serine/threonine protein kinase	384
641163432	1012	26.82	35	311	2	289	7.0e-28	119	COG0515	Serine/threonine protein kinase	384
641163434	322	31.76	21	316	4	289	2.0e-34	140	COG0382	4-hydroxybenzoate polyprenyltransferase	289
641163436	235	53.28	7	234	2	222	2.0e-84	305	COG0692	Uracil DNA glycosylase	223
641163437	250	30.61	31	223	1	184	1.0e-36	146	COG0431	NAD(P)H-dependent FMN reductase	184
641163440	100	36.08	4	100	1	97	2.0e-14	70.4	COG1359	Quinol monooxygenase YgiN	100
641163441	312	22.33	1	292	1	296	2.0e-21	96.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641163442	273	27.18	38	223	37	220	1.0e-14	73.8	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
641163443	184	37.16	4	151	2	148	2.0e-27	115	COG1522	DNA-binding transcriptional regulator, Lrp family	154
641163444	404	28.33	1	229	20	249	1.0e-17	84.5	COG2966	Uncharacterized membrane protein YjjP, DUF1212 family	250
641163446	244	35.41	21	229	4	200	3.0e-35	142	COG2454	Uncharacterized protein	211
641163447	482	32.96	13	446	6	432	5.0e-73	268	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
641163448	363	25.77	1	350	3	327	1.0e-30	127	COG1466	DNA polymerase III, delta subunit	334
641163449	112	53.41	23	110	1	88	5.0e-12	63	COG0268	Ribosomal protein S20	88
641163450	223	37.57	53	217	2	157	4.0e-38	151	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
641163454	47	65.91	1	44	15	57	5.0e-10	56	COG0333	Ribosomal protein L32	57
641163455	395	33.33	9	380	3	337	2.0e-65	243	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
641163456	322	47.42	10	318	2	310	2.0e-83	302	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
641163457	218	46.85	2	217	34	251	7.0e-35	140	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641163458	78	55.13	1	78	2	79	6.0e-11	59.2	COG0236	Acyl carrier protein	80
641163459	414	56.66	3	413	2	412	0.0e+00	485	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
641163460	155	44.67	1	149	1	143	5.0e-36	143	COG0698	Ribose 5-phosphate isomerase RpiB	151
641163461	235	49.19	1	124	30	153	6.0e-35	141	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
641163462	366	45.25	149	365	1	216	2.0e-44	173	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
641163462	366	55.8	10	147	8	145	6.0e-45	175	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
641163463	216	50	12	216	2	196	3.0e-57	215	COG0307	Riboflavin synthase alpha chain	204
641163464	383	58.42	7	208	3	203	2.0e-74	272	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
641163465	449	42.03	9	441	6	388	1.0e-82	300	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
641163466	464	45.65	227	404	1	179	1.0e-38	154	COG1573	Uracil-DNA glycosylase	202
641163467	241	32.04	1	103	2	93	4.0e-07	48.6	COG0776	Bacterial nucleoid DNA-binding protein	94
641163470	220	26.86	1	174	4	175	4.0e-10	58.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641163473	365	42.47	5	363	4	344	1.0e-94	339	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
641163474	416	52.11	41	395	1	353	2.0e-120	425	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
641163475	128	44.16	5	81	11	87	1.0e-18	85.2	COG1862	Preprotein translocase subunit YajC	97
641163477	540	41.7	231	451	83	305	1.0e-55	211	COG0341	Preprotein translocase subunit SecF	305
641163478	602	35.41	72	564	2	474	5.0e-88	318	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
641163479	459	14.58	86	418	26	347	3.0e-06	46.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
641163480	532	20.45	27	507	12	472	6.0e-18	85.9	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
641163483	279	25.44	1	278	18	291	5.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
641163485	141	32.84	9	141	2	134	6.0e-22	96.8	COG0848	Biopolymer transport protein ExbD	137
641163486	229	26.83	7	211	16	216	2.0e-26	112	COG0811	Biopolymer transport protein ExbB/TolQ	216
641163491	703	24.36	51	672	30	619	3.0e-62	233	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
641163493	723	32.7	18	720	47	765	3.0e-125	443	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
641163494	955	28.57	50	347	2	287	2.0e-31	131	COG0515	Serine/threonine protein kinase	384
641163497	182	30.73	5	182	2	177	6.0e-23	100	COG3797	Uncharacterized conserved protein, DUF1697 family	178
641163499	550	43.15	4	388	5	379	3.0e-81	296	COG4402	Uncharacterized protein	457
641163501	243	39.66	11	239	3	228	9.0e-42	163	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641163502	441	39.32	1	435	1	439	3.0e-100	359	COG0165	Argininosuccinate lyase	459
641163503	666	23.27	3	228	35	277	3.0e-20	93.9	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
641163503	666	28.38	294	666	44	409	7.0e-56	212	COG2124	Cytochrome P450	411
641163504	678	37.36	407	672	47	317	3.0e-49	190	COG3207	Pyoverdine/dityrosine biosynthesis protein Dit1	330
641163505	219	38.65	8	214	1	179	8.0e-28	117	COG3803	Uncharacterized conserved protein, DUF924 family	182
641163507	363	24.81	43	295	37	272	2.0e-26	113	COG3207	Pyoverdine/dityrosine biosynthesis protein Dit1	330
641163513	260	42.29	4	256	3	251	4.0e-67	248	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
641163514	344	37.35	6	339	1	328	1.0e-44	173	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
641163515	306	23.7	1	286	8	312	5.0e-22	98.4	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
641163519	361	30.61	145	336	33	228	2.0e-20	93.8	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
641163520	893	34.85	572	765	41	238	2.0e-25	111	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
641163522	764	37.93	15	560	27	550	1.0e-122	434	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
641163523	220	23.39	1	213	1	205	8.0e-14	70.6	COG0625	Glutathione S-transferase	211
641163524	343	19.23	1	253	1	232	7.0e-07	48.4	COG1893	Ketopantoate reductase	307
641163530	300	25.27	21	291	1	277	3.0e-16	79.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641163541	354	25.57	1	339	23	366	1.0e-32	134	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
641163552	369	28.79	46	349	2	313	4.0e-31	129	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641163553	634	34.09	1	479	1	456	5.0e-102	365	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
641163555	912	26.22	1	310	3	282	2.0e-36	148	COG0515	Serine/threonine protein kinase	384
641163559	318	26.26	43	317	2	288	1.0e-27	117	COG0515	Serine/threonine protein kinase	384
641163560	2029	21.15	381	2029	120	1619	3.0e-98	354	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
641163561	337	25.21	136	336	90	313	2.0e-16	80.2	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641163562	550	30.67	35	319	2	294	9.0e-48	184	COG0515	Serine/threonine protein kinase	384
641163565	650	25.61	1	356	13	376	4.0e-40	160	COG0515	Serine/threonine protein kinase	384
641163567	303	29.47	4	300	3	296	3.0e-31	129	COG0583	DNA-binding transcriptional regulator, LysR family	297
641163570	332	26.84	3	327	2	305	4.0e-34	138	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641163571	608	28.98	32	400	2	375	7.0e-44	172	COG0515	Serine/threonine protein kinase	384
641163572	104	57.3	13	101	1	88	2.0e-18	84	COG5552	Uncharacterized protein	88
641163586	388	32.97	269	359	2	92	5.0e-07	49.2	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641163588	158	35.97	4	140	7	103	2.0e-18	85	COG4323	Uncharacterized protein	105
641163589	207	32.6	4	179	1	181	5.0e-18	84.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641163591	182	28.38	1	148	16	156	4.0e-11	61.2	COG3666	Transposase	161
641163594	1247	22.89	791	1189	63	450	6.0e-15	77.1	COG2319	WD40 repeat	466
641163595	335	25.9	94	331	36	271	3.0e-32	132	COG3183	Predicted restriction endonuclease, HNH family	272
641163597	342	18.08	82	327	37	250	1.0e-08	54.2	COG3591	V8-like Glu-specific endopeptidase	251
641163599	477	45.34	10	462	5	457	1.0e-129	456	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641163600	302	23.97	151	289	8	153	3.0e-07	49.2	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
641163601	150	31.61	3	148	1	154	3.0e-15	74.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
641163603	268	27.97	31	265	13	233	2.0e-22	100	COG2859	Uncharacterized protein	237
641163606	430	34.77	45	399	33	392	1.0e-61	230	COG0019	Diaminopimelate decarboxylase	394
641163615	339	28.86	99	289	16	216	3.0e-17	82.8	COG0705	Membrane associated serine protease, rhomboid family	228
641163616	389	44.86	1	370	3	365	1.0e-101	363	COG4748	Uncharacterized protein	365
641163617	253	30.83	16	245	48	311	2.0e-37	149	COG1397	ADP-ribosylglycohydrolase	314
641163622	474	26.72	96	452	44	375	7.0e-29	122	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
641163623	721	23.65	43	413	2	384	5.0e-43	169	COG0515	Serine/threonine protein kinase	384
641163624	389	37.54	53	386	16	339	3.0e-51	196	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
641163625	303	28.91	1	294	4	286	2.0e-45	176	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
641163626	311	33.11	11	302	2	289	7.0e-50	191	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
641163627	121	61.82	1	110	7	116	2.0e-42	164	COG3564	Uncharacterized conserved protein, DUF779 family	116
641163628	506	42.83	19	501	1	472	0.0e+00	484	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641163633	230	55.11	1	225	3	216	1.0e-79	289	COG0036	Pentose-5-phosphate-3-epimerase	220
641163635	619	30	4	619	5	577	7.0e-99	355	COG0018	Arginyl-tRNA synthetase	577
641163637	270	32.36	1	267	69	336	4.0e-36	144	COG1075	Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold	336
641163638	322	22.55	43	315	16	283	1.0e-13	71.3	COG5380	Lipase chaperone LimK	283
641163644	661	26.61	29	379	30	367	6.0e-30	126	COG1680	CubicO group peptidase, beta-lactamase class C family	390
641163646	326	27.36	38	321	2	281	3.0e-36	146	COG0515	Serine/threonine protein kinase	384
641163650	198	36.42	20	177	7	168	1.0e-34	139	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
641163651	251	36.8	1	250	17	266	9.0e-40	157	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
641163652	259	33.59	4	259	11	264	6.0e-45	174	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
641163653	265	47.67	6	262	2	253	6.0e-84	304	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
641163654	356	26.28	6	308	12	302	1.0e-18	87.8	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
641163658	352	29.2	232	344	1	113	5.0e-08	52.3	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641163660	568	59.75	4	567	2	528	0.0e+00	778	COG4108	Peptide chain release factor RF-3	528
641163662	262	27.64	31	204	44	238	2.0e-11	63.4	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
641163669	331	38.81	63	330	11	257	9.0e-73	267	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
641163670	319	31.21	5	318	7	311	2.0e-40	159	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
641163671	211	36.59	4	204	1	201	3.0e-25	108	COG0625	Glutathione S-transferase	211
641163676	272	32.48	46	268	31	246	3.0e-27	115	COG0356	FoF1-type ATP synthase, membrane subunit a	246
641163679	417	18.85	3	365	2	340	9.0e-07	48.6	COG0644	Dehydrogenase (flavoprotein)	396
641163680	486	31.8	99	353	91	336	1.0e-32	134	COG0642	Signal transduction histidine kinase	336
641163681	311	50	5	311	2	304	2.0e-91	329	COG0492	Thioredoxin reductase	305
641163683	142	21.99	10	126	3	135	1.0e-05	42.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
641163684	279	32.69	120	275	1	154	2.0e-24	106	COG3449	DNA gyrase inhibitor GyrI	154
641163684	279	36.7	4	112	15	123	2.0e-21	96.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641163692	104	36	5	104	2	96	1.0e-17	81.4	COG1534	RNA-binding protein YhbY	97
641163693	251	34.36	1	251	4	261	3.0e-44	171	COG0300	Short-chain dehydrogenase	265
641163695	264	25	1	264	7	254	4.0e-07	49	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
641163699	313	23.89	27	242	20	237	9.0e-21	94.7	COG0421	Spermidine synthase	282
641163702	263	36.68	10	263	6	254	8.0e-53	200	COG0631	Serine/threonine protein phosphatase PrpC	262
641163703	371	35.77	11	368	6	370	4.0e-57	215	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
641163705	560	20	197	559	16	380	7.0e-11	62.6	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
641163709	356	45.19	18	223	8	210	2.0e-53	202	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
641163710	119	45.16	42	103	4	65	5.0e-09	53.1	COG2608	Copper chaperone CopZ	71
641163714	121	29.46	1	109	1	95	9.0e-06	42.5	COG0858	Ribosome-binding factor A	118
641163716	185	53.26	1	184	3	186	3.0e-54	204	COG0233	Ribosome recycling factor	187
641163717	247	66.38	6	239	4	238	4.0e-92	330	COG0528	Uridylate kinase	238
641163719	301	59.38	19	242	3	225	4.0e-93	334	COG0052	Ribosomal protein S2	252
641163723	621	23.98	45	393	1	360	4.0e-39	156	COG0515	Serine/threonine protein kinase	384
641163726	246	27.66	43	221	24	185	7.0e-20	91.2	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
641163730	141	58.39	5	141	3	138	3.0e-44	170	COG3565	Predicted dioxygenase of extradiol dioxygenase family	138
641163731	348	41.59	11	329	4	314	2.0e-87	315	COG0180	Tryptophanyl-tRNA synthetase	314
641163737	337	29.79	57	337	2	283	6.0e-36	144	COG0515	Serine/threonine protein kinase	384
641163741	201	31.82	25	191	7	180	2.0e-13	69.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641163746	543	36.25	17	543	19	498	2.0e-94	339	COG3104	Dipeptide/tripeptide permease	498
641163747	236	23.61	1	232	3	206	2.0e-19	89.2	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
641163750	662	26.95	102	566	9	443	3.0e-53	203	COG2027	D-alanyl-D-alanine carboxypeptidase	470
641163753	448	17.71	261	444	35	216	5.0e-06	46.1	COG2755	Lysophospholipase L1 or related esterase	216
641163754	560	28.57	2	385	1	364	6.0e-56	212	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
641163756	567	28.9	19	567	11	527	2.0e-61	230	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641163759	202	33.14	16	184	6	177	1.0e-19	89.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641163763	285	30	23	258	1	237	4.0e-26	112	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
641163765	715	29.48	173	499	2	340	2.0e-44	174	COG0515	Serine/threonine protein kinase	384
641163769	130	55.65	7	130	3	126	9.0e-46	175	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
641163771	320	27.67	90	310	76	310	2.0e-20	93.7	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641163776	1036	27.27	32	342	2	282	2.0e-35	145	COG0515	Serine/threonine protein kinase	384
641163777	212	27.75	8	180	4	176	7.0e-19	87.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641163781	203	48.73	4	200	5	181	1.0e-46	179	COG3803	Uncharacterized conserved protein, DUF924 family	182
641163783	262	40	143	257	6	120	3.0e-17	82.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641163785	576	37.69	317	575	5	231	5.0e-43	169	COG1018	Ferredoxin-NADP reductase	266
641163786	142	26.95	13	138	1	137	5.0e-06	43.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
641163787	304	32.32	4	296	3	297	2.0e-31	129	COG0583	DNA-binding transcriptional regulator, LysR family	297
641163791	206	32.78	3	178	1	178	3.0e-19	88.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641163793	1184	31.54	59	338	2	282	1.0e-40	162	COG0515	Serine/threonine protein kinase	384
641163795	374	35.09	257	370	3	116	4.0e-11	62.7	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641163796	452	38.85	3	447	2	454	2.0e-115	409	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
641163806	818	22.54	433	779	32	448	6.0e-26	113	COG3119	Arylsulfatase A or related enzyme	475
641163812	205	39.01	27	204	1	182	2.0e-29	122	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641163816	498	28.23	39	315	2	277	7.0e-34	138	COG0515	Serine/threonine protein kinase	384
641163820	591	39.18	1	262	6	262	5.0e-56	212	COG0631	Serine/threonine protein phosphatase PrpC	262
641163823	460	30.28	32	169	22	160	1.0e-08	54.7	COG3666	Transposase	161
641163832	1128	24.82	682	1072	7	400	2.0e-33	138	COG1228	Imidazolonepropionase or related amidohydrolase	406
641163834	72	51.39	1	72	1	72	2.0e-18	83.7	COG0361	Translation initiation factor IF-1	75
641163835	211	36.59	17	177	12	175	1.0e-22	99.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641163836	962	27.83	364	666	2	322	4.0e-42	167	COG0515	Serine/threonine protein kinase	384
641163837	315	35.29	1	313	1	313	6.0e-58	218	COG0039	Malate/lactate dehydrogenase	313
641163838	163	38.75	6	162	4	163	3.0e-28	118	COG1247	L-amino acid N-acyltransferase YncA	169
641163843	584	24.7	48	358	2	284	4.0e-35	142	COG0515	Serine/threonine protein kinase	384
641163847	296	22.5	65	255	36	231	4.0e-10	58.8	COG4233	Thiol-disulfide interchange protein, contains DsbC and DsbD domains	273
641163848	243	26.06	101	230	5	135	3.0e-08	52.5	COG1225	Peroxiredoxin	157
641163849	318	39.64	201	311	3	113	8.0e-15	74.7	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641163853	286	34.96	152	274	5	127	7.0e-19	88	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641163854	209	31.16	3	206	1	211	8.0e-23	100	COG0625	Glutathione S-transferase	211
641163856	763	28.66	104	396	2	312	1.0e-39	158	COG0515	Serine/threonine protein kinase	384
641163860	245	36.84	122	216	1	95	3.0e-14	72.4	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641163862	244	31.25	122	233	1	112	1.0e-13	70.8	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641163864	862	44.48	7	846	6	778	0.0e+00	828	COG0466	ATP-dependent Lon protease, bacterial type	782
641163867	457	25.41	30	309	2	286	1.0e-29	124	COG0515	Serine/threonine protein kinase	384
641163870	322	51.61	8	317	1	305	2.0e-92	332	COG0181	Porphobilinogen deaminase	307
641163875	207	35.43	3	173	1	173	1.0e-19	89.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641163877	744	31.89	257	656	32	442	6.0e-45	176	COG2319	WD40 repeat	466
641163878	499	28.48	65	348	2	290	3.0e-40	159	COG0515	Serine/threonine protein kinase	384
641163882	533	27.11	160	514	68	427	8.0e-31	128	COG5184	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	476
641163883	549	29.01	156	499	105	451	1.0e-32	134	COG5184	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	476
641163884	542	23.66	150	523	56	428	1.0e-28	121	COG5184	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	476
641163886	919	20.93	51	852	18	781	2.0e-08	55.4	COG4258	Predicted exporter	788
641163887	845	41.26	7	690	3	641	0.0e+00	513	COG0210	Superfamily I DNA or RNA helicase	655
641163889	537	25.49	2	502	1	479	2.0e-47	184	COG1233	Phytoene dehydrogenase-related protein	487
641163895	489	45.06	143	485	135	464	2.0e-94	340	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641163898	251	20	16	140	1	124	3.0e-07	49	COG0789	DNA-binding transcriptional regulator, MerR family	124
641163899	402	32.18	54	338	2	266	2.0e-42	167	COG1018	Ferredoxin-NADP reductase	266
641163904	177	26.21	32	175	11	154	3.0e-11	61.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
641163907	378	32.52	216	378	68	227	4.0e-26	112	COG0705	Membrane associated serine protease, rhomboid family	228
641163912	94	37.78	4	93	2	90	3.0e-15	73.5	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
641163914	508	36.96	2	508	20	556	0.0e+00	471	COG0423	Glycyl-tRNA synthetase (class II)	558
641163917	353	25.51	8	282	4	279	2.0e-20	93.4	COG0408	Coproporphyrinogen III oxidase	303
641163918	309	27.57	1	297	1	296	4.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
641163923	397	35.88	13	396	1	392	5.0e-76	278	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641163926	308	30.72	15	305	7	325	1.0e-41	163	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
641163927	336	29.24	1	336	2	324	9.0e-37	147	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
641163928	435	44.11	1	432	2	403	9.0e-99	354	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
641163929	471	47.7	3	456	2	454	4.0e-129	455	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
641163930	1023	30.35	319	770	17	447	6.0e-51	196	COG2319	WD40 repeat	466
641163931	376	24.27	123	315	38	226	2.0e-09	56.9	COG3591	V8-like Glu-specific endopeptidase	251
641163933	336	40.99	12	329	1	307	6.0e-82	297	COG0223	Methionyl-tRNA formyltransferase	307
641163937	123	27.18	1	103	24	114	6.0e-06	43	COG2919	Cell division protein FtsB	117
641163938	680	33.59	431	673	3	249	8.0e-28	119	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641163938	680	48.35	1	423	1	402	6.0e-118	418	COG3347	Rhamnose utilisation protein RhaD, predicted bifunctional aldolase and dehydrogenase	404
641163939	480	20.39	34	321	1	277	1.0e-20	94.5	COG0515	Serine/threonine protein kinase	384
641163940	276	38.04	3	273	18	293	5.0e-51	194	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
641163941	552	43.16	5	326	1	322	5.0e-68	252	COG2376	Dihydroxyacetone kinase	323
641163945	225	31.25	19	225	10	183	1.0e-20	93.3	COG0693	Putative intracellular protease/amidase	188
641163946	302	29.41	1	283	6	290	8.0e-31	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
641163951	401	28.46	46	399	21	378	1.0e-21	97.7	COG1680	CubicO group peptidase, beta-lactamase class C family	390
641163952	483	32.65	5	482	3	474	4.0e-77	282	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
641163964	341	26.55	68	338	4	248	2.0e-20	93.4	COG0492	Thioredoxin reductase	305
641163968	1889	25.76	296	1030	2	718	5.0e-62	234	COG3899	Predicted ATPase	849
641163968	1889	27.56	1610	1888	66	333	3.0e-32	135	COG0642	Signal transduction histidine kinase	336
641163968	1889	28.72	7	266	1	279	3.0e-30	128	COG0515	Serine/threonine protein kinase	384
641163970	462	38.68	4	462	3	447	2.0e-117	416	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
641163971	855	34.48	56	330	2	271	6.0e-43	169	COG0515	Serine/threonine protein kinase	384
641163975	574	30.16	1	568	4	464	1.0e-67	251	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641163978	132	42.64	1	129	4	131	7.0e-31	126	COG1607	Acyl-CoA hydrolase	157
641163981	244	27.67	16	171	8	161	1.0e-11	63.6	COG3666	Transposase	161
641163982	337	27.6	82	273	46	220	2.0e-09	57.3	COG2801	Transposase InsO and inactivated derivatives	232
641163986	254	40.23	1	252	20	264	5.0e-43	168	COG0548	Acetylglutamate kinase	265
641163987	436	31.87	5	434	3	429	2.0e-77	283	COG1253	Hemolysin or related protein, contains CBS domains	429
641163990	331	30.08	4	233	3	218	4.0e-26	112	COG0171	NH3-dependent NAD+ synthetase	268
641163991	683	35.11	19	662	1	638	3.0e-113	403	COG0210	Superfamily I DNA or RNA helicase	655
641163992	842	24.54	212	842	13	617	4.0e-51	196	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
641163995	87	32.91	1	79	1	79	3.0e-07	46.8	COG0236	Acyl carrier protein	80
641163996	642	25.2	64	514	42	524	1.0e-38	155	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
641163997	244	19.18	13	226	8	216	9.0e-08	50.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
641163998	321	41.06	23	317	4	303	4.0e-64	238	COG4261	Predicted acyltransferase, LPLAT superfamily	309
641163999	523	41.3	4	507	1	498	8.0e-116	411	COG2986	Histidine ammonia-lyase	498
641164002	294	27.2	3	252	1	202	3.0e-10	59.5	COG0625	Glutathione S-transferase	211
641164003	819	26.81	7	801	23	788	7.0e-71	262	COG4258	Predicted exporter	788
641164005	409	29.85	6	404	7	409	7.0e-61	228	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
641164007	174	29.49	15	167	10	160	5.0e-14	70.8	COG4706	Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain	161
641164008	251	46.96	17	251	8	251	1.0e-40	159	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641164009	403	41.77	2	402	7	410	9.0e-100	357	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
641164010	406	23.96	7	359	5	342	6.0e-27	115	COG0644	Dehydrogenase (flavoprotein)	396
641164030	789	24.77	476	690	8	204	6.0e-17	83.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641164030	789	36.61	1	295	14	285	5.0e-60	226	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
641164031	384	42.13	5	381	2	390	1.0e-86	313	COG0183	Acetyl-CoA acetyltransferase	392
641164036	207	23.23	22	175	1	151	3.0e-18	85	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
641164040	479	28.04	1	362	2	325	4.0e-35	142	COG1858	Cytochrome c peroxidase	364
641164043	319	34.98	22	316	21	309	2.0e-33	136	COG0657	Acetyl esterase/lipase	312
641164053	204	23.28	4	192	1	189	5.0e-08	51.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641164055	261	30.23	6	258	5	258	5.0e-35	141	COG0300	Short-chain dehydrogenase	265
641164058	195	17.44	2	195	8	196	2.0e-06	45.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641164059	472	33.26	39	467	22	442	1.0e-36	147	COG1538	Outer membrane protein TolC	457
641164061	1076	26.79	21	1054	4	1008	0.0e+00	554	COG0841	Multidrug efflux pump subunit AcrB	1009
641164067	721	34.89	8	549	12	545	7.0e-100	358	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
641164068	176	23.19	17	145	1	138	1.0e-08	53.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
641164069	738	33.33	212	318	7	112	4.0e-10	60.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641164071	434	39.44	215	423	3	203	4.0e-34	139	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
641164073	228	32.05	1	222	1	231	9.0e-32	130	COG0412	Dienelactone hydrolase	236
641164074	530	44.54	82	530	88	549	5.0e-109	388	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
641164075	157	70.2	7	157	5	154	2.0e-56	211	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
641164076	244	28.84	28	241	1	205	1.0e-17	84.1	COG1335	Nicotinamidase-related amidase	205
641164085	456	28.77	19	451	8	441	1.0e-69	257	COG2211	Na+/melibiose symporter or related transporter	467
641164087	227	24.16	25	202	2	179	1.0e-07	50.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641164088	773	48.72	5	726	4	697	0.0e+00	668	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
641164089	207	46.63	5	196	1	187	4.0e-60	224	COG0193	Peptidyl-tRNA hydrolase	190
641164090	201	39.18	8	104	3	93	5.0e-16	78	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
641164091	322	59.62	12	322	5	314	3.0e-119	421	COG0462	Phosphoribosylpyrophosphate synthetase	314
641164093	1082	33.92	50	319	2	278	3.0e-45	178	COG0515	Serine/threonine protein kinase	384
641164094	456	27.63	39	442	16	421	9.0e-61	228	COG0612	Predicted Zn-dependent peptidase	438
641164095	521	24.65	78	501	11	438	1.0e-57	217	COG0612	Predicted Zn-dependent peptidase	438
641164097	646	52.55	20	646	1	597	0.0e+00	744	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
641164098	154	58.44	1	154	1	154	1.0e-50	192	COG2193	Bacterioferritin (cytochrome b1)	157
641164099	662	29.5	127	569	68	505	3.0e-27	117	COG1404	Serine protease, subtilisin family	508
641164100	544	52.3	14	382	1	356	1.0e-112	400	COG3288	NAD/NADP transhydrogenase alpha subunit	356
641164101	482	52.26	4	480	3	463	0.0e+00	542	COG1282	NAD/NADP transhydrogenase beta subunit	463
641164104	401	33.14	14	184	6	179	2.0e-18	87.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641164109	507	43.51	6	503	4	487	2.0e-113	403	COG1530	Ribonuclease G or E	487
641164115	479	25.62	25	425	20	298	3.0e-28	120	COG0379	Quinolinate synthase	324
641164116	757	26.06	1	752	47	764	2.0e-94	340	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
641164117	213	28.38	1	148	16	156	4.0e-11	61.6	COG3666	Transposase	161
641164120	430	22.1	40	369	2	360	8.0e-29	121	COG0515	Serine/threonine protein kinase	384
641164121	176	28.98	3	173	1	176	1.0e-11	63.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641164123	2507	20.25	1444	2154	3	662	8.0e-18	88	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
641164128	369	33.86	124	358	48	287	4.0e-29	122	COG4974	Site-specific recombinase XerD	300
641164134	179	33.33	12	167	18	179	3.0e-18	85.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641164136	128	34.48	20	77	5	62	2.0e-06	44.8	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
641164138	108	35.71	9	64	5	60	2.0e-08	51.4	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
641164159	531	29.73	211	460	49	283	4.0e-20	93.3	COG4974	Site-specific recombinase XerD	300
641164160	647	27.29	237	645	16	428	2.0e-57	217	COG0612	Predicted Zn-dependent peptidase	438
641164162	134	40	15	129	6	124	1.0e-12	65.6	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
641164165	500	37.22	12	492	3	471	6.0e-121	428	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
641164168	347	41.95	3	347	1	340	4.0e-78	285	COG0430	RNA 3'-terminal phosphate cyclase	341
641164169	414	36.38	16	414	4	432	4.0e-106	378	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
641164177	284	31.25	162	273	1	112	9.0e-12	64.3	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641164184	196	22.95	49	166	12	121	6.0e-06	44.2	COG0727	Fe-S-cluster containining protein	132
641164185	346	36.84	251	343	31	125	8.0e-14	71.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641164186	1022	26.81	1	296	13	289	3.0e-30	127	COG0515	Serine/threonine protein kinase	384
641164187	368	24.04	24	341	27	355	1.0e-27	117	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
641164189	601	56.7	22	601	2	528	0.0e+00	608	COG4650	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain	531
641164194	1243	40.07	19	1182	9	1106	0.0e+00	1068	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
641164197	334	41.96	6	332	2	326	8.0e-68	250	COG0714	MoxR-like ATPase	329
641164208	605	28.02	38	472	6	393	2.0e-56	214	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641164211	511	57.41	4	320	2	317	2.0e-102	366	COG0206	Cell division GTPase FtsZ	338
641164212	822	26.38	7	401	7	384	2.0e-55	211	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
641164213	282	41.96	1	280	1	283	7.0e-62	230	COG0169	Shikimate 5-dehydrogenase	283
641164214	444	41.65	1	440	5	438	2.0e-110	393	COG1570	Exonuclease VII, large subunit	440
641164224	572	39.88	89	569	4	487	3.0e-87	316	COG2272	Carboxylesterase type B	491
641164230	194	30.37	7	190	13	202	1.0e-35	142	COG1573	Uracil-DNA glycosylase	202
641164231	199	36.13	41	188	22	176	2.0e-12	65.6	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
641164236	316	36.89	188	309	3	124	1.0e-19	91.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641164237	268	27.7	23	234	55	249	3.0e-13	69.4	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
641164238	303	29.29	4	299	1	290	2.0e-23	103	COG0583	DNA-binding transcriptional regulator, LysR family	297
641164243	335	53.8	2	315	55	360	2.0e-105	375	COG0082	Chorismate synthase	369
641164246	324	26.2	43	295	52	313	3.0e-14	73.1	COG0142	Geranylgeranyl pyrophosphate synthase	322
641164257	391	36.8	61	387	1	328	2.0e-50	193	COG0714	MoxR-like ATPase	329
641164260	314	40.82	203	299	23	120	2.0e-15	76.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641164261	246	42.86	1	233	1	233	1.0e-53	203	COG3967	Short-chain dehydrogenase involved in D-alanine esterification of teichoic acids	245
641164262	188	24.06	1	187	6	192	3.0e-07	48.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641164263	313	29.82	1	309	1	325	4.0e-36	145	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
641164265	609	27.52	7	283	2	279	3.0e-30	127	COG0515	Serine/threonine protein kinase	384
641164267	297	37.39	62	166	22	134	9.0e-22	97.7	COG0295	Cytidine deaminase	134
641164268	849	26.35	38	837	34	759	9.0e-75	275	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
641164270	456	43.74	3	456	2	436	1.0e-101	363	COG0733	Na+-dependent transporter, SNF family	439
641164272	387	40.06	19	367	1	341	5.0e-73	268	COG3191	L-aminopeptidase/D-esterase	348
641164273	674	31.58	367	655	24	317	1.0e-39	158	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
641164274	319	32.22	6	316	5	316	1.0e-38	154	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
641164277	313	26.96	7	286	28	318	4.0e-32	132	COG3608	Predicted deacylase	331
641164278	332	30.28	43	316	35	318	8.0e-38	151	COG3608	Predicted deacylase	331
641164279	390	39.52	8	247	12	259	1.0e-45	177	COG0631	Serine/threonine protein phosphatase PrpC	262
641164280	515	17.92	4	453	22	351	5.0e-18	86.2	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
641164282	578	16.84	53	541	38	458	8.0e-13	69.2	COG0277	FAD/FMN-containing dehydrogenase	459
641164284	213	33.52	1	178	1	181	2.0e-36	145	COG5018	Inhibitor of the KinA pathway to sporulation, predicted exonuclease	210
641164286	155	31.93	22	140	1	116	5.0e-06	44.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
641164287	401	39.62	1	401	1	392	6.0e-74	271	COG0183	Acetyl-CoA acetyltransferase	392
641164288	733	39.93	332	615	3	285	3.0e-61	230	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
641164288	733	41	19	217	8	200	6.0e-38	152	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641164298	333	33.99	137	288	31	173	4.0e-18	85.8	COG1913	Predicted Zn-dependent protease	181
641164299	660	36.52	2	656	75	705	3.0e-128	452	COG0557	Exoribonuclease R	706
641164300	461	27.13	164	457	52	357	3.0e-16	80.3	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
641164302	660	44.27	1	648	2	618	0.0e+00	611	COG0326	Molecular chaperone, HSP90 family	623
641164304	346	29.68	119	337	1	212	3.0e-22	99.6	COG0569	Trk K+ transport system, NAD-binding component	225
641164306	186	30.64	11	177	9	181	2.0e-19	89	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641164309	476	23.6	2	476	44	553	4.0e-36	146	COG0747	ABC-type transport system, periplasmic component	556
641164311	629	24.48	42	433	12	397	3.0e-18	87	COG1228	Imidazolonepropionase or related amidohydrolase	406
641164316	406	35	163	404	27	282	3.0e-30	126	COG1408	Predicted phosphohydrolase, MPP superfamily	284
641164322	329	52.34	8	328	5	321	5.0e-100	357	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
641164323	247	28.21	22	246	1	211	4.0e-19	88.5	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
641164326	1033	27.13	62	360	2	281	6.0e-38	153	COG0515	Serine/threonine protein kinase	384
641164329	545	24.07	131	516	29	478	3.0e-38	153	COG3540	Phosphodiesterase/alkaline phosphatase D	522
641164330	1040	26.01	83	386	2	288	2.0e-32	135	COG0515	Serine/threonine protein kinase	384
641164333	641	41.46	1	573	1	557	4.0e-129	455	COG0497	DNA repair ATPase RecN	557
641164334	223	40.69	1	216	1	226	2.0e-36	145	COG2135	Putative SOS response-associated peptidase YedK	226
641164335	461	28.66	8	164	15	178	9.0e-17	81.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641164338	265	25.98	133	259	2	127	1.0e-10	60.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641164339	147	28.91	21	147	2	115	4.0e-16	77.8	COG3791	Uncharacterized conserved protein	133
641164343	684	25.43	140	530	3	365	4.0e-32	133	COG0515	Serine/threonine protein kinase	384
641164346	210	35.45	87	196	3	112	2.0e-10	59.3	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641164352	934	27.67	42	309	2	284	3.0e-34	141	COG0515	Serine/threonine protein kinase	384
641164354	207	30.22	4	184	1	182	7.0e-16	77.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641164355	623	30.54	5	431	15	441	4.0e-63	236	COG0534	Na+-driven multidrug efflux pump	455
641164362	359	29.67	4	334	1	322	2.0e-40	160	COG3520	Predicted component of the type VI protein secretion system	335
641164363	593	34.94	2	588	5	616	3.0e-109	389	COG3519	Type VI protein secretion system component VasA	621
641164364	127	29.63	4	117	9	143	2.0e-10	58	COG3518	Predicted component of the type VI protein secretion system	157
641164365	445	21.02	111	373	68	360	2.0e-08	53.6	COG0515	Serine/threonine protein kinase	384
641164371	216	33.66	19	216	48	248	2.0e-24	106	COG1338	Flagellar biosynthetic protein FliP	248
641164373	95	52.86	25	94	1	70	2.0e-17	81.1	COG3530	Uncharacterized conserved protein, DUF3820 family	71
641164374	143	53.33	1	135	1	116	2.0e-32	131	COG0203	Ribosomal protein L17	116
641164375	337	48.26	14	330	1	314	2.0e-96	345	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
641164376	202	53.47	2	202	9	205	7.0e-54	203	COG0522	Ribosomal protein S4 or related protein	205
641164377	99	69.7	1	99	31	129	4.0e-36	143	COG0100	Ribosomal protein S11	129
641164378	123	64.75	1	122	1	121	9.0e-40	155	COG0099	Ribosomal protein S13	121
641164380	438	50.34	1	430	7	435	2.0e-120	426	COG0201	Preprotein translocase subunit SecY	436
641164381	167	54	4	146	2	151	6.0e-31	126	COG0200	Ribosomal protein L15	152
641164382	64	61.11	5	58	1	54	7.0e-15	72.1	COG1841	Ribosomal protein L30/L7E	55
641164383	166	61.08	1	166	15	181	4.0e-56	210	COG0098	Ribosomal protein S5	181
641164384	122	46.28	3	122	5	125	2.0e-27	114	COG0256	Ribosomal protein L18	125
641164385	180	51.7	1	176	1	176	6.0e-53	200	COG0097	Ribosomal protein L6P/L9E	178
641164386	131	52.27	1	131	1	132	5.0e-44	169	COG0096	Ribosomal protein S8	132
641164387	212	55.87	34	212	1	179	3.0e-63	234	COG0094	Ribosomal protein L5	180
641164388	105	59.05	1	104	2	104	2.0e-22	97.7	COG0198	Ribosomal protein L24	104
641164389	122	65.57	1	122	1	122	8.0e-47	178	COG0093	Ribosomal protein L14	122
641164390	89	51.19	5	88	3	86	2.0e-19	87.6	COG0186	Ribosomal protein S17	87
641164391	67	37.88	2	67	4	69	3.0e-07	46.8	COG0255	Ribosomal protein L29	69
641164392	138	62.77	1	135	2	138	4.0e-46	176	COG0197	Ribosomal protein L16/L10AE	146
641164393	225	55.78	12	208	1	199	2.0e-66	245	COG0092	Ribosomal protein S3	233
641164394	113	50	1	106	10	115	4.0e-28	116	COG0091	Ribosomal protein L22	120
641164395	91	64.84	1	91	1	91	4.0e-33	132	COG0185	Ribosomal protein S19	93
641164396	274	61.45	1	274	1	275	9.0e-103	366	COG0090	Ribosomal protein L2	275
641164397	95	40.86	3	94	1	93	3.0e-22	96.8	COG0089	Ribosomal protein L23	94
641164398	218	42.86	1	205	1	210	9.0e-49	186	COG0088	Ribosomal protein L4	214
641164399	101	64	1	100	2	101	2.0e-35	140	COG0051	Ribosomal protein S10	104
641164400	401	72.07	1	401	1	394	0.0e+00	644	COG0050	Translation elongation factor EF-Tu, a GTPase	394
641164401	724	49.1	7	723	5	693	0.0e+00	729	COG0480	Translation elongation factor EF-G, a GTPase	697
641164402	164	62.2	31	157	22	148	4.0e-45	174	COG0049	Ribosomal protein S7	148
641164403	123	74.8	1	123	7	129	1.0e-45	174	COG0048	Ribosomal protein S12	129
641164404	1400	48.02	20	856	7	808	0.0e+00	836	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
641164406	127	62.9	4	127	2	124	2.0e-24	104	COG0222	Ribosomal protein L7/L12	124
641164407	174	34.1	1	172	3	175	3.0e-24	104	COG0244	Ribosomal protein L10	175
641164408	241	56.39	7	232	2	228	2.0e-81	295	COG0081	Ribosomal protein L1	228
641164409	139	63.04	2	139	2	139	1.0e-50	191	COG0080	Ribosomal protein L11	141
641164410	176	46.47	3	171	10	175	2.0e-40	158	COG0250	Transcription antitermination factor NusG	178
641164414	54	58	5	54	1	50	4.0e-07	46.4	COG0267	Ribosomal protein L33	50
641164424	229	30.33	1	122	10	131	1.0e-16	80	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
641164426	124	30.91	1	110	14	123	6.0e-14	70	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
641164427	468	40	11	442	9	438	2.0e-95	343	COG3572	Gamma-glutamylcysteine synthetase	456
641164429	365	34.42	1	324	2	334	2.0e-69	256	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
641164434	284	39.24	2	237	32	257	4.0e-56	211	COG0005	Purine nucleoside phosphorylase	262
641164435	305	25.51	6	277	1	289	3.0e-20	92.6	COG0524	Sugar or nucleoside kinase, ribokinase family	311
641164436	240	25	7	229	2	205	1.0e-19	90	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
641164439	526	40.26	1	519	1	520	5.0e-108	385	COG4146	Uncharacterized membrane permease YidK, sodium:solute symporter family	571
641164442	264	35.61	1	261	1	259	4.0e-48	185	COG0300	Short-chain dehydrogenase	265
641164449	414	30.21	9	233	15	247	4.0e-24	105	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
641164450	280	24.72	13	276	19	276	3.0e-09	56.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641164453	175	26.8	12	108	20	113	2.0e-10	59.4	COG1917	Cupin domain protein related to quercetin dioxygenase	131
641164454	347	35.77	225	346	1	122	6.0e-15	75.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641164460	994	24.46	61	372	2	288	1.0e-32	135	COG0515	Serine/threonine protein kinase	384
641164462	590	31.62	121	466	100	446	4.0e-50	193	COG5002	Signal transduction histidine kinase	459
641164463	466	50.77	9	458	2	454	0.0e+00	471	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641164469	663	25.89	341	613	23	259	1.0e-18	88.9	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
641164472	543	21.88	13	543	1	536	3.0e-33	136	COG2303	Choline dehydrogenase or related flavoprotein	542
641164475	53	42.31	1	52	3	54	1.0e-07	48	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
641164480	419	35.15	48	414	1	313	1.0e-67	250	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
641164481	409	30.13	1	366	27	373	3.0e-49	189	COG2124	Cytochrome P450	411
641164484	350	26.27	13	230	23	276	9.0e-12	64.8	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
641164486	326	32.11	2	326	1	351	6.0e-67	247	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
641164487	337	32.47	2	336	18	361	5.0e-51	194	COG0687	Spermidine/putrescine-binding periplasmic protein	363
641164492	1238	31.65	11	267	2	274	7.0e-34	140	COG0515	Serine/threonine protein kinase	384
641164493	425	20.08	9	250	2	206	2.0e-11	64.5	COG0406	Broad specificity phosphatase PhoE	208
641164503	616	38.93	29	611	7	573	0.0e+00	538	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
641164506	1297	46.99	828	1288	7	481	0.0e+00	504	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
641164507	324	38.44	1	296	6	305	3.0e-48	185	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
641164508	214	41.63	4	212	3	211	3.0e-45	175	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
641164517	461	41.74	5	454	3	455	9.0e-123	433	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
641164522	220	50.45	1	219	7	226	1.0e-72	266	COG1136	ABC-type lipoprotein export system, ATPase component	226
641164525	336	33.83	7	328	8	323	2.0e-58	220	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
641164528	281	22.18	10	281	8	280	2.0e-15	76.7	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
641164535	588	33.33	70	344	2	279	1.0e-46	181	COG0515	Serine/threonine protein kinase	384
641164537	213	36.27	14	213	4	207	1.0e-34	139	COG0406	Broad specificity phosphatase PhoE	208
641164538	260	36.76	1	253	1	236	4.0e-26	112	COG0368	Cobalamin synthase	246
641164539	358	44.13	5	352	17	336	2.0e-58	220	COG2038	NaMN:DMB phosphoribosyltransferase	347
641164542	551	33.68	22	292	2	282	3.0e-49	189	COG0515	Serine/threonine protein kinase	384
641164543	323	37.25	1	306	1	290	3.0e-72	265	COG3781	Predicted membrane chloride channel, bestrophin family	306
641164546	533	23.18	6	348	11	369	2.0e-24	107	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
641164547	367	44.98	70	356	26	308	7.0e-51	194	COG0657	Acetyl esterase/lipase	312
641164548	365	42.45	42	357	1	312	4.0e-53	202	COG0657	Acetyl esterase/lipase	312
641164549	626	24.93	144	480	2	350	4.0e-36	146	COG0515	Serine/threonine protein kinase	384
641164553	260	32.37	2	242	4	217	4.0e-25	108	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
641164554	621	36.48	42	598	12	528	7.0e-100	358	COG1574	Predicted amidohydrolase YtcJ	535
641164557	293	25	28	287	3	237	3.0e-12	66.1	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
641164562	375	26.46	9	360	26	367	8.0e-11	61.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
641164563	1078	28.57	25	1068	7	1009	0.0e+00	571	COG0841	Multidrug efflux pump subunit AcrB	1009
641164565	446	27.42	27	444	28	408	2.0e-47	184	COG2124	Cytochrome P450	411
641164567	191	33.54	17	176	20	179	2.0e-18	85.4	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
641164568	430	22.42	58	430	41	373	3.0e-17	83.4	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
641164569	345	34.74	156	340	1	154	3.0e-34	139	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
641164579	555	17.51	72	519	3	411	5.0e-09	56.5	COG1232	Protoporphyrinogen oxidase	444
641164580	560	44.4	27	547	2	506	0.0e+00	460	COG4262	Predicted spermidine synthase with an N-terminal membrane domain	508
641164588	407	30.81	8	353	5	345	7.0e-38	151	COG0644	Dehydrogenase (flavoprotein)	396
641164589	243	50.65	85	235	8	161	5.0e-55	207	COG0225	Peptide methionine sulfoxide reductase MsrA	174
641164591	654	27.08	228	503	95	336	5.0e-25	109	COG0642	Signal transduction histidine kinase	336
641164592	548	22.15	8	312	22	339	2.0e-21	97.8	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
641164595	403	20.39	137	338	1	195	5.0e-10	59.1	COG0400	Predicted esterase	207
641164597	325	26.36	3	318	2	284	2.0e-28	119	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
641164598	875	29.52	131	860	9	725	2.0e-90	327	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
641164598	875	45.76	2	119	40	150	4.0e-31	130	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
641164599	1175	36.11	633	1170	3	553	2.0e-115	411	COG2192	Predicted carbamoyl transferase, NodU family	555
641164600	304	20.08	42	300	28	284	2.0e-14	73.5	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
641164610	485	31.32	109	377	1	274	2.0e-38	153	COG0515	Serine/threonine protein kinase	384
641164612	461	50.97	1	461	1	457	0.0e+00	492	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641164614	273	34.48	157	272	2	117	3.0e-12	66.2	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641164616	793	25.08	450	771	2	272	2.0e-21	98.3	COG0515	Serine/threonine protein kinase	384
641164617	302	29.03	1	268	1	273	9.0e-37	147	COG0266	Formamidopyrimidine-DNA glycosylase	273
641164623	194	35.91	16	193	7	184	2.0e-22	98.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
641164624	798	24.81	672	798	9	137	3.0e-16	81.5	COG1017	Hemoglobin-like flavoprotein	150
641164624	798	27.65	14	293	1	282	8.0e-40	159	COG0515	Serine/threonine protein kinase	384
641164624	798	36.36	369	456	5	91	6.0e-15	76.6	COG0633	Ferredoxin	102
641164627	350	50	9	336	2	329	2.0e-104	372	COG0240	Glycerol-3-phosphate dehydrogenase	329
641164633	218	31.87	10	190	1	182	2.0e-17	82.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641164634	960	27.95	52	323	2	278	2.0e-32	135	COG0515	Serine/threonine protein kinase	384
641164637	893	18.54	268	880	115	717	2.0e-31	131	COG1033	Predicted exporter protein, RND superfamily	727
641164645	888	28.07	2	267	5	282	2.0e-39	158	COG0515	Serine/threonine protein kinase	384
641164647	247	25.76	21	218	6	198	7.0e-11	61.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641164649	421	22.61	5	421	7	407	2.0e-32	133	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
641164650	411	23.75	1	409	9	406	2.0e-38	153	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
641164663	807	15.73	393	760	53	365	5.0e-10	60.4	COG1680	CubicO group peptidase, beta-lactamase class C family	390
641164664	185	21.71	5	156	10	161	1.0e-05	43.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641164677	468	38.86	19	468	8	446	8.0e-91	328	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
641164678	364	40.29	21	364	5	316	7.0e-55	207	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
641164679	306	28.24	2	295	21	313	4.0e-35	142	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641164680	680	21.72	1	235	3	243	6.0e-19	89.9	COG1651	Protein-disulfide isomerase	244
641164681	395	43.12	7	388	5	388	3.0e-118	418	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
641164685	283	32.58	1	216	12	223	4.0e-27	115	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641164687	349	27.92	60	298	1	198	2.0e-21	96.8	COG0625	Glutathione S-transferase	211
641164688	1909	25.97	15	302	1	305	1.0e-35	146	COG0515	Serine/threonine protein kinase	384
641164688	1909	27.17	307	1101	2	750	3.0e-63	238	COG3899	Predicted ATPase	849
641164691	301	34.8	3	294	2	292	1.0e-38	153	COG0583	DNA-binding transcriptional regulator, LysR family	297
641164695	182	28.38	1	148	16	156	4.0e-11	61.2	COG3666	Transposase	161
641164697	382	24.51	5	363	5	331	1.0e-22	101	COG0644	Dehydrogenase (flavoprotein)	396
641164700	168	26.51	8	166	11	173	2.0e-08	51.8	COG1510	DNA-binding transcriptional regulator GbsR, MarR family	177
641164701	297	30.28	162	295	8	149	8.0e-07	48	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
641164711	576	36.88	2	573	3	562	9.0e-101	361	COG1966	Carbon starvation protein CstA	575
641164717	316	50.16	2	312	56	364	4.0e-106	378	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
641164721	169	53.61	3	166	2	166	9.0e-51	192	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
641164723	102	28.95	4	101	30	143	2.0e-11	60.4	COG0071	Molecular chaperone IbpA, HSP20 family	146
641164724	148	29.17	8	146	1	144	7.0e-17	80	COG0071	Molecular chaperone IbpA, HSP20 family	146
641164725	326	31.11	1	315	5	305	1.0e-53	203	COG1208	NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins	358
641164727	439	52.14	1	420	1	409	0.0e+00	527	COG1004	UDP-glucose 6-dehydrogenase	414
641164733	470	47.7	51	459	26	425	2.0e-117	416	COG0141	Histidinol dehydrogenase	425
641164734	374	36.83	3	371	2	348	8.0e-62	231	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
641164737	476	31.41	83	475	29	409	1.0e-54	207	COG4826	Serine protease inhibitor	410
641164739	516	25.94	46	414	34	325	2.0e-32	133	COG1858	Cytochrome c peroxidase	364
641164741	814	21.52	83	461	21	351	2.0e-26	114	COG0019	Diaminopimelate decarboxylase	394
641164742	421	23.84	7	421	28	435	1.0e-22	101	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
641164744	1005	26.28	43	354	2	285	9.0e-34	139	COG0515	Serine/threonine protein kinase	384
641164745	367	40.94	47	320	1	265	3.0e-57	216	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
641164746	177	46.06	1	165	1	164	2.0e-44	171	COG0242	Peptide deformylase	168
641164753	264	34.67	1	263	3	266	2.0e-42	166	COG0388	Predicted amidohydrolase	274
641164754	381	41.6	15	381	20	390	1.0e-92	333	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
641164755	443	28.25	49	443	25	393	3.0e-55	209	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
641164758	264	24.85	10	168	7	174	1.0e-10	60.8	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
641164760	338	25.37	70	331	61	316	8.0e-28	118	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
641164761	495	23.35	134	491	9	382	6.0e-25	109	COG1680	CubicO group peptidase, beta-lactamase class C family	390
641164762	149	33.11	2	149	6	151	1.0e-20	92.4	COG4704	Uncharacterized conserved protein, DUF2141 family	151
641164764	287	47.42	1	286	1	283	7.0e-88	317	COG0414	Panthothenate synthetase	285
641164765	297	56.44	1	264	4	267	7.0e-103	367	COG0413	Ketopantoate hydroxymethyltransferase	268
641164768	314	25.68	1	287	1	296	4.0e-26	112	COG0583	DNA-binding transcriptional regulator, LysR family	297
641164773	798	21.2	47	765	40	763	7.0e-16	79.6	COG5373	Uncharacterized membrane protein	931
641164774	355	42.42	40	302	1	260	4.0e-66	245	COG1180	Pyruvate-formate lyase-activating enzyme	260
641164775	196	30.93	7	191	6	194	7.0e-26	110	COG2078	Uncharacterized conserved protein, AMMECR1 domain	203
641164776	270	33.21	6	265	2	278	9.0e-44	170	COG1355	Predicted class III extradiol dioxygenase, MEMO1 family	279
641164777	480	32.24	33	453	5	402	4.0e-62	232	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
641164778	400	24	33	399	37	372	3.0e-36	146	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
641164779	312	25.53	32	306	16	282	1.0e-09	57.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641164781	600	41.82	46	425	3	383	1.0e-80	294	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641164785	295	25.21	85	292	84	310	1.0e-13	70.6	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641164786	369	24.4	148	366	77	310	1.0e-15	77.9	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641164796	806	33.98	221	758	188	756	2.0e-89	323	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
641164797	1236	29.84	124	782	67	759	2.0e-99	358	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
641164799	1221	29.84	169	795	104	759	9.0e-89	322	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
641164801	177	29.21	1	173	5	182	3.0e-13	68.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641164802	590	35.27	63	588	30	541	2.0e-106	380	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
641164805	368	25.1	1	236	3	227	2.0e-18	86.7	COG0705	Membrane associated serine protease, rhomboid family	228
641164807	366	49.55	8	336	1	318	2.0e-101	362	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
641164808	301	39.08	22	282	4	253	3.0e-63	235	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
641164809	286	41.84	1	281	1	273	2.0e-64	239	COG0266	Formamidopyrimidine-DNA glycosylase	273
641164810	220	36.13	13	203	1	182	2.0e-25	109	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641164817	422	45.08	3	418	74	480	6.0e-120	424	COG0260	Leucyl aminopeptidase	485
641164818	217	32.54	2	127	1	120	9.0e-19	87.2	COG1539	Dihydroneopterin aldolase	121
641164819	879	33.49	5	869	45	839	0.0e+00	472	COG1643	HrpA-like RNA helicase	845
641164820	86	43.24	10	83	2	75	2.0e-14	70.6	COG1918	Fe2+ transport system protein FeoA	75
641164821	697	43.16	1	695	1	652	0.0e+00	580	COG0370	Fe2+ transport system protein B	653
641164822	318	36.54	4	302	1	296	1.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
641164823	732	70.49	1	732	12	730	0.0e+00	1121	COG0376	Catalase (peroxidase I)	730
641164825	325	48.47	1	322	27	347	1.0e-95	343	COG0407	Uroporphyrinogen-III decarboxylase	352
641164827	400	24.92	12	323	3	276	2.0e-23	103	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
641164828	333	22.83	12	284	3	306	7.0e-25	108	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
641164829	311	25.08	7	299	11	302	2.0e-23	103	COG1575	1,4-dihydroxy-2-naphthoate octaprenyltransferase	303
641164830	239	33.68	47	239	2	180	3.0e-26	112	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641164832	330	35.99	22	305	2	286	9.0e-41	160	COG1562	Phytoene/squalene synthetase	288
641164833	500	33.26	2	477	8	474	2.0e-81	296	COG1233	Phytoene dehydrogenase-related protein	487
641164836	237	34.54	16	236	2	250	9.0e-42	163	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
641164837	386	39.48	8	378	3	387	6.0e-85	308	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641164839	704	23.8	245	703	173	617	1.0e-43	172	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
641164843	384	41.86	6	384	5	388	2.0e-87	315	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641164844	279	32.62	75	260	58	243	3.0e-29	122	COG1360	Flagellar motor protein MotB	244
641164851	136	21.9	5	133	3	138	3.0e-07	47.9	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
641164852	174	38.33	17	136	1	120	2.0e-19	88.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641164853	168	40.85	1	69	1	71	1.0e-09	56.5	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
641164855	407	33.99	4	398	20	411	4.0e-64	238	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
641164856	626	27.93	133	458	16	327	3.0e-28	120	COG0642	Signal transduction histidine kinase	336
641164857	207	33.52	8	179	1	176	4.0e-20	91.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641164859	1033	25.23	89	400	2	281	2.0e-36	147	COG0515	Serine/threonine protein kinase	384
641164860	291	27.36	1	286	63	348	3.0e-37	149	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
641164862	208	36.94	88	198	3	113	5.0e-14	71.6	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641164868	330	26.48	14	262	2	221	5.0e-19	88.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641164870	418	29.02	5	270	78	363	9.0e-29	121	COG1680	CubicO group peptidase, beta-lactamase class C family	390
641164874	1030	28.77	54	326	2	277	5.0e-36	147	COG0515	Serine/threonine protein kinase	384
641164876	373	29.37	92	362	84	359	2.0e-33	137	COG3852	Signal transduction histidine kinase, nitrogen specific	363
641164877	426	31.3	13	353	16	343	2.0e-43	170	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
641164880	317	23.37	9	299	1	289	1.0e-21	97	COG0583	DNA-binding transcriptional regulator, LysR family	297
641164881	126	25	1	116	1	120	1.0e-05	42.2	COG3070	Transcriptional regulator of competence genes, TfoX/Sxy family	121
641164882	417	29.62	1	365	2	343	5.0e-45	175	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
641164883	300	25.91	2	289	1	297	8.0e-18	84.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
641164884	88	34.62	8	80	13	90	1.0e-07	47.7	COG0633	Ferredoxin	102
641164885	383	35.37	1	382	25	408	4.0e-62	232	COG2124	Cytochrome P450	411
641164892	395	26.71	65	392	65	379	3.0e-24	106	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
641164893	328	33.67	215	312	1	98	3.0e-08	53.1	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641164895	294	49.65	11	294	2	284	3.0e-90	325	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
641164896	748	18.43	1	737	3	768	9.0e-22	99.2	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
641164899	175	48.78	1	162	28	190	3.0e-41	161	COG3812	Uncharacterized protein	193
641164900	1010	27.83	35	346	2	278	6.0e-34	140	COG0515	Serine/threonine protein kinase	384
641164902	302	29.55	24	300	2	281	5.0e-35	141	COG0515	Serine/threonine protein kinase	384
641164905	349	26.82	32	321	4	297	5.0e-31	128	COG0492	Thioredoxin reductase	305
641164906	249	31.2	123	247	1	125	4.0e-19	88.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641164910	182	24.57	1	163	50	220	2.0e-16	78.6	COG1451	Predicted metal-dependent hydrolase	223
641164922	445	27.24	63	308	2	277	2.0e-28	120	COG0515	Serine/threonine protein kinase	384
641164924	374	25	99	349	28	285	3.0e-19	89.9	COG4974	Site-specific recombinase XerD	300
641164925	691	30.98	17	686	9	649	6.0e-126	445	COG2766	Predicted Ser/Thr protein kinase	649
641164926	369	28.71	6	366	16	416	5.0e-63	235	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
641164927	507	29.98	7	494	15	489	3.0e-101	362	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
641164928	248	25.1	8	246	2	230	9.0e-24	104	COG1794	Aspartate/glutamate racemase	230
641164932	483	30.74	6	471	4	468	2.0e-54	206	COG0591	Na+/proline symporter	493
641164934	453	34.44	1	451	3	435	1.0e-97	350	COG0621	tRNA A37 methylthiotransferase MiaB	437
641164936	199	20.81	2	198	8	201	4.0e-06	45	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641164937	256	50.44	5	227	3	227	2.0e-62	232	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641164938	615	30.94	169	579	31	446	2.0e-58	220	COG5002	Signal transduction histidine kinase	459
641164939	230	36.09	1	230	1	229	2.0e-36	145	COG0704	Phosphate uptake regulator	240
641164941	232	53.16	1	158	1	154	9.0e-43	166	COG1720	tRNA (Thr-GGU) A37 N-methylase	156
641164943	323	20.27	19	310	27	312	2.0e-14	73.2	COG3239	Fatty acid desaturase	343
641164944	566	24.73	37	378	2	360	1.0e-22	101	COG0515	Serine/threonine protein kinase	384
641164950	230	24.71	10	179	8	173	1.0e-06	46.9	COG3226	DNA-binding transcriptional regulator YbjK	204
641164952	353	19.72	6	268	4	271	5.0e-17	82.1	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
641164956	783	30.03	434	772	1	335	1.0e-39	159	COG0642	Signal transduction histidine kinase	336
641164958	229	25	22	225	48	274	3.0e-16	78.9	COG0790	TPR repeat	292
641164959	530	45.89	180	529	5	353	1.0e-92	334	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
641164960	436	28.27	69	336	2	278	3.0e-37	149	COG0515	Serine/threonine protein kinase	384
641164961	360	41.94	1	359	15	369	8.0e-92	330	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
641164962	157	60.13	1	153	9	161	2.0e-51	195	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
641164968	299	33.11	10	299	2	293	1.0e-26	113	COG0583	DNA-binding transcriptional regulator, LysR family	297
641164969	263	35.19	13	119	11	116	5.0e-20	92	COG4922	Predicted SnoaL-like aldol condensation-catalyzing enzyme	129
641164970	192	29.07	17	187	4	155	3.0e-17	81.8	COG1225	Peroxiredoxin	157
641164972	350	28.92	170	332	30	177	2.0e-07	50.7	COG4195	Phage-related replication protein YjqB, UPF0714/DUF867 family	208
641164979	477	25.71	43	456	25	375	2.0e-42	167	COG0006	Xaa-Pro aminopeptidase	384
641164983	487	36.15	41	412	29	366	1.0e-75	277	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
641164984	312	37.18	79	310	22	246	5.0e-41	161	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
641164986	363	36.94	13	360	6	337	3.0e-51	195	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
641164988	195	23.4	1	188	6	189	8.0e-09	53.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641164989	248	36.47	3	246	2	251	3.0e-35	142	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641164991	753	25.83	32	476	14	458	2.0e-43	171	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
641164991	753	29.13	521	748	28	250	1.0e-32	135	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
641164992	360	36.34	19	358	4	308	6.0e-46	178	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641164994	455	38.43	22	452	65	475	4.0e-81	295	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
641164995	266	43.35	1	262	1	251	6.0e-57	214	COG1521	Pantothenate kinase type III	251
641164997	231	33	29	231	21	207	5.0e-34	137	COG0400	Predicted esterase	207
641165007	211	32.98	12	202	2	176	1.0e-19	90.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165008	179	36.78	1	174	20	180	4.0e-24	104	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165010	280	43.89	20	273	3	260	6.0e-69	254	COG0708	Exonuclease III	261
641165013	316	30.89	1	316	1	326	7.0e-38	151	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
641165014	140	35.88	1	131	1	128	6.0e-17	79.9	COG1939	23S rRNA maturation mini-RNase III	132
641165016	347	21.95	129	307	33	228	4.0e-09	56	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641165018	537	24.08	18	525	3	480	1.0e-48	187	COG1233	Phytoene dehydrogenase-related protein	487
641165019	286	22.13	9	238	27	259	2.0e-06	46.8	COG0668	Small-conductance mechanosensitive channel	316
641165020	1832	18.91	1	417	7	442	1.0e-38	156	COG0531	Amino acid transporter	466
641165023	331	26.04	47	329	1	282	9.0e-21	94.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641165024	253	35.97	16	251	2	251	1.0e-22	100	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641165025	305	25.42	7	304	1	296	4.0e-23	102	COG0583	DNA-binding transcriptional regulator, LysR family	297
641165027	458	33.91	13	413	11	377	8.0e-73	267	COG0498	Threonine synthase	411
641165029	235	38.56	1	234	6	224	2.0e-45	176	COG2013	Uncharacterized conserved protein, AIM24 family	227
641165030	232	37.83	1	228	6	225	4.0e-46	178	COG2013	Uncharacterized conserved protein, AIM24 family	227
641165031	228	39.11	1	223	6	225	7.0e-44	170	COG2013	Uncharacterized conserved protein, AIM24 family	227
641165033	1055	23.24	440	1028	4	530	8.0e-39	156	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641165036	454	26.19	142	393	57	287	5.0e-12	66.3	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
641165038	174	33.33	1	162	9	175	7.0e-21	93.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165040	304	26	13	293	2	282	7.0e-31	127	COG0515	Serine/threonine protein kinase	384
641165041	388	26.81	4	329	1	297	2.0e-33	137	COG1397	ADP-ribosylglycohydrolase	314
641165044	259	38.7	1	259	3	247	8.0e-50	190	COG1496	Copper oxidase (laccase) domain	249
641165046	247	33.94	86	244	13	171	6.0e-27	114	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
641165048	262	31.9	143	258	1	116	3.0e-08	52.3	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641165051	509	26.85	41	468	1	436	2.0e-63	237	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
641165052	206	25.48	4	206	1	205	1.0e-08	53.7	COG0625	Glutathione S-transferase	211
641165053	162	50.32	1	157	1	155	1.0e-52	198	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
641165054	765	25.75	70	753	36	724	6.0e-72	266	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
641165056	408	43.49	3	399	2	404	1.0e-94	340	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
641165057	691	28.48	1	148	3	150	3.0e-15	77.7	COG0822	NifU homolog involved in Fe-S cluster formation	150
641165057	691	33.53	166	501	3	269	2.0e-31	131	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
641165058	315	21.67	1	315	10	329	2.0e-23	103	COG3239	Fatty acid desaturase	343
641165059	273	27.56	139	265	1	127	8.0e-17	81.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641165062	1318	32.5	21	278	1	273	5.0e-42	167	COG0515	Serine/threonine protein kinase	384
641165063	272	32.06	14	264	9	256	4.0e-39	155	COG0584	Glycerophosphoryl diester phosphodiesterase	257
641165066	536	33.27	1	529	6	502	7.0e-85	308	COG1070	Sugar (pentulose or hexulose) kinase	502
641165067	209	39.08	39	206	3	176	2.0e-19	89.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165069	603	25.06	13	387	7	384	4.0e-35	143	COG1680	CubicO group peptidase, beta-lactamase class C family	390
641165072	339	24.93	5	336	3	331	2.0e-32	133	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
641165074	286	30.28	166	274	4	112	8.0e-08	51.6	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641165075	261	32.97	13	260	9	279	8.0e-23	100	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641165077	309	32.67	8	299	3	294	4.0e-33	135	COG0583	DNA-binding transcriptional regulator, LysR family	297
641165079	466	33.33	16	459	6	432	6.0e-84	304	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
641165082	384	32.23	55	384	50	353	5.0e-50	192	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
641165085	517	31.93	350	515	25	190	1.0e-28	121	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
641165087	682	16.44	102	632	1	500	7.0e-14	73.1	COG0366	Glycosidase	505
641165089	99	25.93	11	86	4	83	2.0e-09	54.5	COG3615	Uncharacterized protein/domain, possibly involved in tellurite resistance	99
641165090	310	31.6	3	307	10	295	6.0e-49	187	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
641165091	536	36.29	15	492	3	487	2.0e-122	432	COG2368	Aromatic ring hydroxylase	493
641165092	194	32.16	1	166	5	175	7.0e-20	90.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165096	677	23.61	193	601	1	422	3.0e-36	147	COG0366	Glycosidase	505
641165098	273	32.95	130	217	5	92	1.0e-07	50.4	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641165099	344	33.06	223	343	1	124	3.0e-13	69.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641165101	717	21.62	216	685	1	504	3.0e-36	147	COG0366	Glycosidase	505
641165103	607	21.69	34	487	2	391	2.0e-37	151	COG0366	Glycosidase	505
641165104	358	49.15	1	352	1	338	4.0e-111	395	COG3839	ABC-type sugar transport system, ATPase component	338
641165105	741	27.14	9	393	10	412	2.0e-46	181	COG2182	Maltose-binding periplasmic protein MalE	420
641165105	741	31.35	440	740	7	294	5.0e-54	206	COG1175	ABC-type sugar transport system, permease component	295
641165106	288	37.37	1	288	3	282	4.0e-62	231	COG3833	ABC-type maltose transport system, permease component	282
641165110	419	29.32	27	417	1	378	2.0e-55	210	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
641165112	165	26.71	4	145	9	131	3.0e-08	51.5	COG3787	Uncharacterized conserved protein YhbP, UPF0306 family	145
641165113	463	36.55	22	456	5	398	5.0e-75	275	COG1301	Na+/H+-dicarboxylate symporter	415
641165114	619	29.4	244	616	6	360	7.0e-56	212	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
641165115	340	38.4	7	250	1	250	2.0e-61	229	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
641165125	504	23.23	244	476	18	270	3.0e-14	73.6	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
641165127	171	35.71	1	151	17	169	2.0e-18	85.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165128	452	23.39	14	245	13	244	1.0e-06	48.4	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
641165132	98	33.33	5	91	4	90	8.0e-13	65.4	COG1359	Quinol monooxygenase YgiN	100
641165133	267	34.9	1	188	5	196	3.0e-38	152	COG0300	Short-chain dehydrogenase	265
641165138	1082	25.3	52	363	2	282	3.0e-32	134	COG0515	Serine/threonine protein kinase	384
641165140	210	36.93	9	180	1	176	1.0e-19	89.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165141	324	27.08	1	285	1	285	5.0e-24	105	COG0583	DNA-binding transcriptional regulator, LysR family	297
641165143	266	25.34	127	258	9	148	4.0e-11	62.2	COG1225	Peroxiredoxin	157
641165144	545	28.79	328	516	48	244	7.0e-23	102	COG1651	Protein-disulfide isomerase	244
641165145	704	29.9	276	465	53	244	5.0e-23	103	COG1651	Protein-disulfide isomerase	244
641165146	480	28.36	244	432	46	243	2.0e-16	81	COG1651	Protein-disulfide isomerase	244
641165149	737	26.82	23	477	10	460	3.0e-40	160	COG2268	Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain	548
641165152	398	52.49	9	388	3	367	0.0e+00	494	COG0505	Carbamoylphosphate synthase small subunit	368
641165153	278	31.66	12	265	3	246	1.0e-36	146	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
641165155	334	25.8	55	334	1	253	3.0e-36	146	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
641165156	695	47.23	282	623	5	344	4.0e-100	359	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
641165157	367	48.87	1	354	2	349	5.0e-109	388	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
641165159	587	35.53	359	585	3	213	6.0e-28	119	COG2114	Adenylate cyclase, class 3	227
641165160	508	33.09	16	276	2	271	9.0e-43	168	COG0515	Serine/threonine protein kinase	384
641165163	1066	28.03	1	1021	2	1009	0.0e+00	538	COG0841	Multidrug efflux pump subunit AcrB	1009
641165169	236	26.07	14	234	27	258	2.0e-17	83.1	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
641165171	316	28.3	5	313	2	311	3.0e-21	96.1	COG0679	Predicted permease	311
641165172	224	35.76	58	206	31	181	7.0e-16	77.4	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
641165174	325	36.04	11	292	13	281	3.0e-53	202	COG0421	Spermidine synthase	282
641165175	410	25.07	79	392	97	447	4.0e-15	76.2	COG5310	Homospermidine synthase	481
641165179	239	29.2	9	231	2	225	6.0e-15	74.6	COG1842	Phage shock protein A	225
641165187	172	32.61	56	147	4	95	4.0e-06	44.6	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641165193	813	21.34	5	311	90	398	8.0e-13	69.6	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
641165196	94	53.49	7	92	5	90	1.0e-24	104	COG1254	Acylphosphatase	92
641165197	935	22.22	1	465	15	436	4.0e-41	163	COG0612	Predicted Zn-dependent peptidase	438
641165199	437	35.65	18	434	94	475	6.0e-69	255	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
641165200	383	30.26	158	383	4	228	2.0e-38	153	COG5587	Uncharacterized conserved protein, DUF2461 family	228
641165201	206	32.2	2	178	1	175	5.0e-21	94.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165203	206	39.18	11	204	17	201	3.0e-34	138	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
641165204	190	43.21	7	168	1	152	4.0e-36	144	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
641165205	813	33.95	28	770	1	691	2.0e-101	364	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
641165208	202	42.5	1	200	1	187	7.0e-44	170	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
641165209	245	40.08	5	245	2	227	1.0e-59	223	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
641165213	360	61.32	3	351	2	349	0.0e+00	515	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
641165217	182	27.04	28	182	19	177	4.0e-15	74.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165222	170	30.77	67	156	23	112	3.0e-06	45	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
641165225	458	22.39	41	429	55	436	4.0e-19	89.9	COG2271	Sugar phosphate permease	448
641165228	310	43.21	13	292	2	266	1.0e-67	250	COG3220	Uncharacterized conserved protein, UPF0276 family	282
641165229	276	21.58	44	276	11	235	1.0e-05	43.8	COG3219	Uncharacterized protein	237
641165230	310	30.17	19	309	1	282	1.0e-16	80.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641165233	207	22.73	6	181	5	176	7.0e-06	44.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641165235	328	41.98	12	317	12	324	4.0e-67	248	COG0435	Glutathionyl-hydroquinone reductase	324
641165238	340	37.01	37	338	10	294	1.0e-60	227	COG1162	Putative ribosome biogenesis GTPase RsgA	301
641165239	408	37.53	7	406	3	399	4.0e-101	361	COG0137	Argininosuccinate synthase	403
641165242	151	32.43	1	143	1	148	1.0e-16	78.8	COG4539	Uncharacterized membrane protein YGL010W	180
641165251	308	39.58	20	275	68	348	5.0e-57	214	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
641165252	644	45.11	20	413	15	401	3.0e-103	369	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
641165253	147	36.91	2	143	1	149	5.0e-23	100	COG1438	Arginine repressor	150
641165255	206	24.23	15	206	6	199	8.0e-09	53.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641165256	354	22.62	74	278	54	301	3.0e-14	73.1	COG1566	Multidrug resistance efflux pump	352
641165257	1034	35.68	2	1004	12	1009	0.0e+00	851	COG0841	Multidrug efflux pump subunit AcrB	1009
641165258	565	26.74	213	556	105	443	5.0e-27	116	COG1538	Outer membrane protein TolC	457
641165263	175	22.37	1	152	25	176	2.0e-07	49.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641165264	229	29.59	19	213	45	229	6.0e-20	91.1	COG5031	Ubiquinone biosynthesis protein Coq4	235
641165267	374	33.53	16	348	1	301	3.0e-54	206	COG1162	Putative ribosome biogenesis GTPase RsgA	301
641165270	292	28.96	1	290	1	272	2.0e-34	139	COG0266	Formamidopyrimidine-DNA glycosylase	273
641165272	389	29.2	12	384	2	381	3.0e-35	143	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
641165279	487	47.4	10	486	4	460	0.0e+00	482	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641165280	480	35.89	3	452	1	420	3.0e-89	322	COG0124	Histidyl-tRNA synthetase	429
641165284	424	29.35	26	414	1	385	2.0e-47	183	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
641165285	930	29.15	34	336	2	281	3.0e-37	151	COG0515	Serine/threonine protein kinase	384
641165287	267	21.77	4	249	2	204	6.0e-06	45.2	COG0625	Glutathione S-transferase	211
641165289	350	45.85	1	349	40	383	4.0e-99	354	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
641165290	302	32.43	5	299	1	294	7.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
641165291	349	23.4	20	331	6	290	2.0e-07	50.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
641165292	408	32.05	21	391	9	367	9.0e-29	121	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
641165294	428	49.37	30	427	1	390	1.0e-122	433	COG0372	Citrate synthase	390
641165296	640	28.4	42	525	13	463	3.0e-53	203	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641165297	227	25.56	1	180	1	180	6.0e-06	44.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641165298	805	16.87	3	794	1	749	3.0e-21	97.7	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
641165307	304	31.41	13	280	61	331	1.0e-39	157	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
641165308	350	40.62	1	344	1	326	2.0e-72	266	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
641165313	437	29.97	67	361	39	323	3.0e-41	163	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
641165315	741	46.69	65	739	60	701	0.0e+00	699	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
641165318	514	25.12	60	483	4	436	3.0e-45	176	COG0612	Predicted Zn-dependent peptidase	438
641165319	474	25.3	39	449	14	421	2.0e-54	207	COG0612	Predicted Zn-dependent peptidase	438
641165323	409	47.43	1	346	8	354	9.0e-81	294	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
641165324	254	35.16	8	254	9	258	4.0e-31	128	COG0725	ABC-type molybdate transport system, periplasmic component	258
641165326	275	49.76	52	260	1	211	8.0e-47	180	COG4149	ABC-type molybdate transport system, permease component	225
641165328	407	27.92	22	298	15	268	1.0e-10	61.5	COG3503	Uncharacterized membrane protein	323
641165330	296	32.64	10	290	1	284	1.0e-16	80.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
641165340	358	55.69	14	353	3	338	2.0e-118	419	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
641165341	502	49.8	1	495	1	482	0.0e+00	610	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
641165342	513	52.29	13	507	5	475	3.0e-127	449	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
641165343	99	38.2	8	96	6	92	3.0e-10	57.1	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
641165345	272	31.44	17	237	2	227	3.0e-25	109	COG1994	Zn-dependent protease (includes SpoIVFB)	230
641165347	377	65.88	1	375	2	382	0.0e+00	634	COG0192	S-adenosylmethionine synthetase	388
641165351	476	49.46	1	466	2	454	0.0e+00	496	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
641165352	405	52.09	1	404	1	404	4.0e-110	391	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
641165353	927	48.53	11	925	14	905	0.0e+00	1081	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
641165354	402	35.32	158	398	1	251	7.0e-42	165	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
641165355	422	28.68	28	422	15	390	3.0e-52	199	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
641165365	741	72.33	1	741	2	742	0.0e+00	1197	COG2838	Monomeric isocitrate dehydrogenase	744
641165367	267	24.32	8	265	3	292	2.0e-27	116	COG1234	Ribonuclease BN, tRNA processing enzyme	292
641165369	270	27.88	41	254	21	241	7.0e-09	54.9	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
641165373	165	55	1	139	12	151	2.0e-42	164	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
641165377	804	22.11	30	785	15	747	2.0e-45	177	COG3973	DNA helicase IV	747
641165385	783	33.07	416	781	47	385	2.0e-64	240	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
641165385	783	37.65	3	410	2	378	2.0e-85	310	COG0116	23S rRNA G2445 N2-methylase RlmL	381
641165387	177	33.55	11	164	7	145	7.0e-23	100	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
641165394	603	26.96	139	564	54	450	5.0e-46	179	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
641165395	324	25.43	36	319	19	285	5.0e-28	118	COG0863	DNA modification methylase	302
641165396	348	26.09	91	346	28	293	2.0e-13	70.1	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
641165398	336	22.54	81	273	30	240	3.0e-08	52.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641165400	317	42.42	1	296	3	268	1.0e-84	306	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
641165402	294	33.21	12	283	5	277	3.0e-48	185	COG3220	Uncharacterized conserved protein, UPF0276 family	282
641165404	656	18.87	1	422	1	381	6.0e-14	73.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
641165405	930	27.56	1	585	1	528	3.0e-58	220	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
641165408	431	30.27	99	424	54	358	4.0e-45	175	COG1858	Cytochrome c peroxidase	364
641165410	460	23.64	11	405	5	459	2.0e-20	93.6	COG1233	Phytoene dehydrogenase-related protein	487
641165411	154	25	7	154	3	148	4.0e-09	54.5	COG1610	Uncharacterized conserved protein YqeY	148
641165412	244	26	17	216	5	181	1.0e-11	63.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165415	258	30.6	20	241	10	237	6.0e-19	87.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641165418	318	33.87	3	314	5	292	1.0e-65	243	COG1131	ABC-type multidrug transport system, ATPase component	293
641165419	403	34.58	1	395	10	401	6.0e-62	231	COG2124	Cytochrome P450	411
641165420	123	33.04	1	115	2	101	7.0e-15	72.7	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
641165422	464	42.22	34	462	40	484	2.0e-114	406	COG0260	Leucyl aminopeptidase	485
641165423	631	47.69	1	409	1	396	0.0e+00	481	COG0282	Acetate kinase	396
641165423	631	54.59	418	613	16	209	6.0e-63	236	COG4869	Propanediol utilization protein	210
641165424	256	41.15	1	253	6	251	3.0e-51	195	COG0631	Serine/threonine protein phosphatase PrpC	262
641165425	401	28.03	15	328	2	255	1.0e-36	147	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
641165428	647	25	57	285	47	280	1.0e-09	58.6	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
641165429	74	38.57	5	74	2	70	1.0e-09	55	COG1826	Sec-independent protein translocase protein TatA	94
641165433	610	29.59	326	610	118	408	1.0e-49	191	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
641165434	483	26.79	40	482	22	406	7.0e-46	178	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
641165440	210	39.13	6	205	3	201	1.0e-38	153	COG0125	Thymidylate kinase	208
641165444	360	43.65	28	333	4	296	3.0e-89	322	COG1159	GTPase Era, involved in 16S rRNA processing	298
641165445	487	44.42	26	473	2	440	0.0e+00	471	COG1160	Predicted GTPases	444
641165446	266	35.97	25	265	6	256	7.0e-40	157	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
641165450	393	22.13	40	388	59	362	2.0e-13	70.6	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
641165452	618	49.34	367	518	3	154	8.0e-36	145	COG1225	Peroxiredoxin	157
641165457	571	26.91	187	534	5	348	6.0e-25	109	COG4962	Pilus assembly protein, ATPase of CpaF family	355
641165461	285	36.23	1	265	5	255	5.0e-50	191	COG0631	Serine/threonine protein phosphatase PrpC	262
641165474	161	51.52	1	160	1	165	1.0e-52	198	COG0678	Peroxiredoxin	165
641165479	367	22.98	8	237	4	194	1.0e-06	47.5	COG0625	Glutathione S-transferase	211
641165480	438	37.73	11	435	2	391	1.0e-61	230	COG0183	Acetyl-CoA acetyltransferase	392
641165481	502	39.37	255	496	3	248	3.0e-39	156	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641165483	641	29.37	46	483	7	388	8.0e-58	218	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641165484	237	26.23	2	184	1	181	5.0e-09	55	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641165489	2181	37.18	3	1027	37	1031	0.0e+00	661	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
641165493	175	32.58	1	175	4	181	2.0e-18	85.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165495	322	25.09	44	319	9	282	4.0e-12	65.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641165500	308	28.83	16	278	49	317	9.0e-25	107	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
641165503	302	41.55	2	295	5	296	3.0e-65	242	COG0109	Polyprenyltransferase (heme O synthase)	304
641165504	225	29.41	27	210	22	200	1.0e-22	99.7	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
641165507	1157	25.4	899	1146	8	191	1.0e-32	135	COG0437	Fe-S-cluster-containing dehydrogenase component	203
641165508	464	19.14	49	455	17	396	7.0e-18	85.8	COG5557	Ni/Fe-hydrogenase 2 integral membrane subunit HybB	401
641165513	288	24.43	52	223	40	207	2.0e-16	80.1	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
641165514	339	30.83	220	339	6	131	3.0e-06	46.1	COG3474	Cytochrome c2	135
641165514	339	33.47	16	246	12	235	5.0e-44	171	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
641165515	542	45.78	18	542	4	534	0.0e+00	471	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
641165516	223	31.08	1	222	6	206	3.0e-32	131	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
641165518	369	42.52	31	369	1	322	2.0e-84	306	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
641165519	123	27.68	2	112	18	128	2.0e-12	64.9	COG2332	Cytochrome c-type biogenesis protein CcmE	153
641165520	683	35.18	6	672	5	635	1.0e-111	397	COG1138	Cytochrome c biogenesis factor	648
641165523	240	43.13	10	218	5	215	1.0e-46	180	COG1131	ABC-type multidrug transport system, ATPase component	293
641165524	718	18.29	24	709	70	768	3.0e-20	94.2	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
641165525	331	36.29	207	329	1	123	3.0e-16	79.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641165529	594	26.22	19	592	20	521	1.0e-43	172	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
641165533	833	25.2	22	389	2	364	8.0e-37	149	COG1680	CubicO group peptidase, beta-lactamase class C family	390
641165538	440	62.18	11	440	4	432	0.0e+00	577	COG0001	Glutamate-1-semialdehyde aminotransferase	432
641165539	898	53.39	1	853	4	804	0.0e+00	963	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
641165541	137	31.09	6	121	10	125	3.0e-10	57.7	COG5622	Protein required for attachment to host cells	139
641165542	1047	28.15	142	434	2	286	2.0e-37	151	COG0515	Serine/threonine protein kinase	384
641165543	383	44.08	62	361	37	333	7.0e-68	251	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
641165544	624	21.35	29	208	36	222	3.0e-08	53.7	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
641165547	212	34.33	8	205	2	197	4.0e-34	138	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
641165550	139	33.93	27	82	5	60	2.0e-06	44.8	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
641165558	393	29.94	1	176	5	181	9.0e-20	91.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165561	297	25	7	297	12	290	3.0e-28	119	COG4667	Predicted phospholipase, patatin/cPLA2 family	292
641165562	708	27.54	98	388	4	282	5.0e-32	132	COG0515	Serine/threonine protein kinase	384
641165564	482	26.79	277	481	22	220	5.0e-08	53.1	COG3770	Murein endopeptidase	284
641165566	1896	26.36	284	1052	1	750	9.0e-67	250	COG3899	Predicted ATPase	849
641165567	240	53.49	13	227	3	217	1.0e-69	256	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
641165569	324	31.65	6	299	2	292	1.0e-33	137	COG0583	DNA-binding transcriptional regulator, LysR family	297
641165579	271	33.72	7	265	7	262	2.0e-47	182	COG0300	Short-chain dehydrogenase	265
641165580	400	32.58	4	393	7	359	2.0e-69	256	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
641165586	219	22.89	16	214	10	201	5.0e-14	71.5	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
641165591	193	28.19	2	181	16	201	4.0e-14	71.4	COG0625	Glutathione S-transferase	211
641165592	178	50.65	5	158	3	152	1.0e-43	169	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
641165593	816	34.27	16	786	1	729	0.0e+00	498	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
641165594	338	30.4	7	335	4	279	9.0e-44	170	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
641165603	132	27.27	1	132	16	140	2.0e-08	51.2	COG3666	Transposase	161
641165609	220	43.66	6	218	2	211	2.0e-51	195	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
641165610	1038	36.64	1	962	63	933	0.0e+00	876	COG0060	Isoleucyl-tRNA synthetase	933
641165613	278	33.7	18	273	9	260	1.0e-31	130	COG0005	Purine nucleoside phosphorylase	262
641165614	345	33.45	10	270	1	275	2.0e-42	166	COG0515	Serine/threonine protein kinase	384
641165615	514	41.86	37	507	1	432	8.0e-118	417	COG0305	Replicative DNA helicase	435
641165616	378	25.98	27	372	1	350	2.0e-38	153	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
641165619	419	24.52	6	412	8	368	3.0e-23	103	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
641165622	432	24.47	68	428	48	423	2.0e-34	140	COG0823	Periplasmic component of the Tol biopolymer transport system	425
641165624	146	32.82	11	141	8	134	6.0e-19	86.8	COG0848	Biopolymer transport protein ExbD	137
641165625	231	35.55	21	228	7	211	2.0e-31	129	COG0811	Biopolymer transport protein ExbB/TolQ	216
641165628	1040	27.33	21	324	2	277	4.0e-32	134	COG0515	Serine/threonine protein kinase	384
641165633	497	28.1	42	489	4	451	2.0e-31	130	COG0531	Amino acid transporter	466
641165639	581	29.35	2	581	3	579	8.0e-107	381	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
641165641	313	42.27	3	310	2	311	9.0e-55	207	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641165642	400	33.08	17	369	9	400	4.0e-63	235	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
641165645	755	29.04	13	264	7	270	3.0e-15	77.6	COG2162	Arylamine N-acetyltransferase	275
641165647	255	23.39	5	207	14	224	3.0e-13	69.2	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
641165648	264	20.16	1	229	11	235	1.0e-09	57.3	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
641165655	325	31.56	75	325	19	279	2.0e-23	103	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641165656	268	23.97	12	266	50	305	2.0e-13	70	COG0657	Acetyl esterase/lipase	312
641165662	316	39.13	44	316	31	303	2.0e-71	263	COG0502	Biotin synthase or related enzyme	335
641165663	339	45.21	8	338	15	348	8.0e-90	324	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
641165664	325	53.42	4	324	2	323	3.0e-128	451	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
641165665	436	43.81	1	433	14	404	1.0e-92	333	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
641165670	288	41.88	6	282	3	264	5.0e-71	261	COG2107	Predicted periplasmic solute-binding protein	272
641165673	411	33.58	16	411	20	411	8.0e-53	201	COG2124	Cytochrome P450	411
641165674	314	25.15	1	314	53	365	1.0e-26	113	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
641165680	451	16.57	5	336	6	305	5.0e-14	72.8	COG0644	Dehydrogenase (flavoprotein)	396
641165683	204	45	1	200	1	179	1.0e-48	186	COG2096	Cob(I)alamin adenosyltransferase	184
641165692	589	55.42	267	587	23	342	7.0e-92	331	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
641165693	798	38.44	4	436	2	414	5.0e-97	349	COG0358	DNA primase (bacterial type)	568
641165696	248	31.88	14	218	8	198	2.0e-29	122	COG0560	Phosphoserine phosphatase	212
641165697	292	50.18	13	290	5	278	1.0e-81	296	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
641165699	209	25.42	5	181	1	176	1.0e-15	76.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165700	954	25.42	58	320	2	282	1.0e-32	135	COG0515	Serine/threonine protein kinase	384
641165705	288	19.69	9	260	7	257	7.0e-13	68.1	COG1729	Periplasmic TolA-binding protein (function unknown)	262
641165708	434	57.81	1	428	1	417	0.0e+00	565	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
641165709	224	45.91	8	219	3	219	1.0e-47	183	COG0040	ATP phosphoribosyltransferase	290
641165711	331	23.55	8	324	6	311	1.0e-15	77.4	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
641165712	498	33.77	127	428	104	402	3.0e-26	113	COG0840	Methyl-accepting chemotaxis protein	408
641165713	354	32.67	22	171	2	148	2.0e-15	77.1	COG1714	Uncharacterized membrane protein YckC, RDD family	172
641165714	371	27.84	120	313	3	196	4.0e-23	102	COG1300	Uncharacterized membrane protein SpoIIM, required for sporulation	207
641165717	324	48.45	7	321	9	329	4.0e-73	268	COG0714	MoxR-like ATPase	329
641165718	460	27.95	1	456	3	416	2.0e-39	156	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
641165719	169	41.52	5	169	1	158	2.0e-40	158	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
641165724	548	30.48	319	524	17	214	4.0e-34	139	COG2114	Adenylate cyclase, class 3	227
641165733	511	19.36	7	469	1	406	6.0e-19	89.3	COG2067	Long-chain fatty acid transport protein	440
641165735	693	40.12	4	660	1	651	0.0e+00	515	COG0210	Superfamily I DNA or RNA helicase	655
641165736	226	26.91	1	203	3	225	5.0e-26	111	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641165738	277	30.36	27	268	5	251	1.0e-12	67.7	COG0730	Uncharacterized membrane protein YfcA	258
641165741	198	33.54	7	165	12	175	8.0e-17	80.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165742	165	30.38	1	154	14	171	1.0e-14	72.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165745	327	44.27	7	324	3	322	3.0e-81	295	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
641165748	455	26.92	1	434	17	396	6.0e-35	142	COG2124	Cytochrome P450	411
641165749	307	34.25	13	226	2	202	7.0e-28	118	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641165751	347	60.4	1	346	2	344	0.0e+00	494	COG0418	Dihydroorotase	344
641165759	200	31.95	13	175	11	179	4.0e-18	84.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165760	500	34.97	30	493	6	416	3.0e-65	242	COG2379	Glycerate-2-kinase	422
641165761	143	28.8	8	132	4	126	1.0e-12	65.8	COG4460	Uncharacterized protein	130
641165766	231	31.11	11	184	2	179	3.0e-14	72.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165767	1894	27.55	54	354	1	305	6.0e-40	161	COG0515	Serine/threonine protein kinase	384
641165767	1894	34.15	1687	1894	36	281	6.0e-33	137	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641165767	1894	36.34	1053	1418	108	466	5.0e-57	217	COG2319	WD40 repeat	466
641165768	975	25.07	54	368	2	288	4.0e-32	134	COG0515	Serine/threonine protein kinase	384
641165769	525	20.45	7	390	7	393	4.0e-18	86.5	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
641165774	182	34.1	9	181	14	182	2.0e-19	89.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165778	606	21.53	142	471	89	443	2.0e-21	98.1	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
641165780	564	26.05	14	506	20	488	2.0e-46	180	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
641165785	521	24.15	5	260	3	257	5.0e-26	112	COG2006	Uncharacterized conserved protein, DUF362 family	293
641165793	299	21.65	3	254	10	287	2.0e-12	67.1	COG0515	Serine/threonine protein kinase	384
641165794	328	26.69	17	317	25	329	1.0e-38	153	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
641165796	2242	21.91	962	1230	55	335	9.0e-09	57.6	COG1413	HEAT repeat	335
641165799	587	33.14	1	345	4	346	1.0e-62	234	COG1290	Cytochrome b subunit of the bc complex	381
641165800	197	25.9	18	181	2	167	2.0e-14	72.1	COG0723	Rieske Fe-S protein	177
641165801	615	27.42	26	381	20	365	2.0e-36	147	COG1680	CubicO group peptidase, beta-lactamase class C family	390
641165806	489	31.11	41	468	6	428	1.0e-65	243	COG0612	Predicted Zn-dependent peptidase	438
641165807	529	23.06	55	469	31	427	2.0e-35	144	COG0612	Predicted Zn-dependent peptidase	438
641165812	559	33.82	18	552	8	527	2.0e-105	376	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641165819	409	34.15	1	407	5	389	9.0e-80	291	COG4398	Small ligand-binding sensory domain FIST	389
641165831	410	42.68	2	397	14	396	3.0e-98	352	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
641165834	877	22.97	34	773	12	743	2.0e-76	281	COG0308	Aminopeptidase N	859
641165835	468	31.48	15	464	26	481	9.0e-78	284	COG0260	Leucyl aminopeptidase	485
641165839	269	33.88	16	256	17	261	2.0e-27	116	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
641165840	512	34.78	18	510	17	497	2.0e-86	313	COG1292	Choline-glycine betaine transporter	537
641165842	346	39.64	7	286	19	282	1.0e-58	220	COG3491	Isopenicillin N synthase and related dioxygenases	322
641165851	213	22	14	213	3	201	5.0e-06	45	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641165852	454	34	1	443	4	411	4.0e-63	235	COG2124	Cytochrome P450	411
641165861	316	21.74	1	284	2	290	1.0e-19	90.7	COG4974	Site-specific recombinase XerD	300
641165868	189	29.35	2	181	1	182	5.0e-10	57.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165869	580	29.05	33	306	2	292	1.0e-34	141	COG0515	Serine/threonine protein kinase	384
641165888	140	25.74	5	120	3	138	1.0e-06	45.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
641165894	1224	27.99	741	1170	14	446	5.0e-44	174	COG2319	WD40 repeat	466
641165895	200	35.2	3	176	1	179	2.0e-20	92.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165896	159	24.32	5	149	11	149	8.0e-06	43.5	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
641165898	605	22.87	172	575	74	451	7.0e-30	125	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
641165899	171	33.12	1	154	5	147	6.0e-19	87.2	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
641165901	686	28.34	175	538	5	359	2.0e-31	131	COG3852	Signal transduction histidine kinase, nitrogen specific	363
641165904	441	27.79	1	437	75	487	1.0e-39	157	COG1233	Phytoene dehydrogenase-related protein	487
641165910	303	27.74	39	302	3	284	8.0e-24	104	COG1408	Predicted phosphohydrolase, MPP superfamily	284
641165912	914	26.03	58	348	1	282	3.0e-30	127	COG0515	Serine/threonine protein kinase	384
641165913	485	30.88	3	484	1	411	1.0e-52	201	COG2124	Cytochrome P450	411
641165919	207	32.14	68	179	2	113	2.0e-12	66.2	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641165920	868	25.29	7	859	2	767	3.0e-68	253	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
641165925	471	26.13	95	316	3	202	9.0e-17	81.9	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
641165927	688	42.42	17	371	1	362	3.0e-99	356	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
641165929	429	25.73	62	428	62	407	3.0e-42	166	COG4826	Serine protease inhibitor	410
641165936	387	46.34	5	382	1	368	4.0e-98	351	COG0263	Glutamate 5-kinase	369
641165937	444	46.17	16	430	9	417	2.0e-121	429	COG0014	Gamma-glutamyl phosphate reductase	417
641165939	324	48.08	1	311	18	312	3.0e-85	308	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
641165942	452	48.87	5	448	2	445	0.0e+00	524	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
641165943	402	28.28	117	383	2	279	1.0e-42	167	COG0287	Prephenate dehydrogenase	279
641165943	402	39.08	23	108	10	96	9.0e-11	61.9	COG1605	Chorismate mutase	101
641165944	334	23.99	24	282	2	294	4.0e-18	85.6	COG0515	Serine/threonine protein kinase	384
641165946	341	29.02	2	306	1	309	8.0e-50	191	COG3392	Adenine-specific DNA methylase	330
641165949	761	30.64	90	724	16	589	2.0e-99	357	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
641165950	377	34.25	20	375	12	373	4.0e-65	242	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
641165955	291	28.42	1	274	9	276	3.0e-24	105	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
641165957	219	23	1	200	2	201	6.0e-07	47.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641165960	857	40.93	162	854	62	728	0.0e+00	583	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
641165964	185	39.87	18	174	1	158	5.0e-34	137	COG3265	Gluconate kinase	161
641165965	399	18.98	67	368	49	363	6.0e-14	72.1	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
641165967	399	26.97	41	272	11	236	5.0e-25	109	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
641165969	493	35.43	203	493	1	285	2.0e-42	167	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
641165969	493	40.86	1	186	4	182	2.0e-42	167	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
641165970	174	47.27	5	157	3	167	9.0e-41	159	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
641165972	333	26.58	7	320	14	295	2.0e-32	133	COG3781	Predicted membrane chloride channel, bestrophin family	306
641165977	505	28.7	161	487	5	336	8.0e-36	145	COG0642	Signal transduction histidine kinase	336
641165978	231	42.98	5	227	2	228	3.0e-47	181	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641165979	270	52.24	17	217	8	206	3.0e-62	232	COG0177	Endonuclease III	211
641165981	196	32.2	1	176	6	181	3.0e-18	85.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641165986	758	22.66	62	749	38	766	3.0e-75	276	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
641165988	361	31	25	353	29	315	3.0e-29	122	COG0530	Ca2+/Na+ antiporter	320
641165990	362	35.22	22	350	12	322	5.0e-66	244	COG0042	tRNA-dihydrouridine synthase	323
641165992	444	27.67	16	171	8	161	1.0e-10	61.2	COG3666	Transposase	161
641165994	403	33.72	42	386	43	369	7.0e-37	148	COG1680	CubicO group peptidase, beta-lactamase class C family	390
641166000	331	22.33	16	331	13	310	1.0e-14	74.3	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
641166002	277	25.53	25	258	9	225	5.0e-14	71.9	COG3541	Predicted nucleotidyltransferase	248
641166007	239	43.28	2	239	7	221	7.0e-62	230	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
641166008	378	33.48	3	221	1	196	3.0e-29	122	COG3483	Tryptophan 2,3-dioxygenase (vermilion)	262
641166009	391	26.21	1	383	2	377	3.0e-26	113	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
641166013	507	27.69	76	356	44	313	2.0e-17	84.1	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641166019	223	31.69	30	212	1	182	4.0e-17	81.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641166026	283	19.63	9	272	10	261	9.0e-19	87.8	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
641166027	578	20.34	27	347	27	367	2.0e-23	104	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
641166029	334	38.25	4	334	3	328	4.0e-64	238	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
641166034	920	32.04	174	910	11	731	4.0e-95	343	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
641166034	920	48.03	1	151	2	147	1.0e-45	178	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
641166035	355	33.64	10	329	9	282	4.0e-31	129	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
641166039	520	33.81	2	417	1	393	1.0e-66	247	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
641166044	213	24.6	23	200	15	199	5.0e-13	68.1	COG0602	Organic radical activating enzyme	212
641166050	415	26.73	9	399	7	402	1.0e-43	171	COG3464	Transposase	402
641166054	498	27.99	71	344	2	291	3.0e-36	146	COG0515	Serine/threonine protein kinase	384
641166059	392	25	72	348	3	285	1.0e-18	88	COG4974	Site-specific recombinase XerD	300
641166060	145	40.97	1	143	1	143	9.0e-30	122	COG1959	DNA-binding transcriptional regulator, IscR family	150
641166075	359	19.77	1	309	2	347	4.0e-11	62.7	COG4637	Predicted ATPase	373
641166076	400	43.65	2	395	14	400	1.0e-98	353	COG1972	Nucleoside permease NupC	404
641166077	802	31.83	29	293	2	287	5.0e-44	173	COG0515	Serine/threonine protein kinase	384
641166077	802	39.01	321	460	12	151	4.0e-25	110	COG5616	TolB amino-terminal domain (function unknown)	152
641166082	508	28.25	109	275	70	243	1.0e-17	84.5	COG1651	Protein-disulfide isomerase	244
641166083	304	24.91	37	304	11	235	2.0e-15	77	COG0412	Dienelactone hydrolase	236
641166084	319	48.08	7	316	2	311	2.0e-101	362	COG0549	Carbamate kinase	312
641166085	296	56.36	3	291	23	310	9.0e-113	399	COG0078	Ornithine carbamoyltransferase	310
641166088	314	30.98	8	301	4	296	7.0e-29	121	COG0583	DNA-binding transcriptional regulator, LysR family	297
641166089	264	38.04	13	262	2	250	6.0e-41	161	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641166100	324	41.03	3	312	2	289	1.0e-62	233	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
641166102	276	39.66	10	238	6	232	1.0e-49	190	COG1489	DNA-binding protein, stimulates sugar fermentation	235
641166103	255	28.11	2	249	19	242	3.0e-22	99.2	COG1647	Esterase/lipase	243
641166104	471	46.57	6	471	5	457	2.0e-128	453	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641166106	351	31.5	6	345	13	351	3.0e-56	212	COG4972	Tfp pilus assembly protein, ATPase PilM	354
641166108	199	22.4	1	188	16	202	2.0e-16	79.2	COG3167	Tfp pilus assembly protein PilO	211
641166111	166	42.86	1	166	10	168	5.0e-33	133	COG0703	Shikimate kinase	172
641166113	352	39.83	1	343	36	351	3.0e-83	302	COG0337	3-dehydroquinate synthetase	360
641166116	185	50	8	181	2	145	2.0e-50	191	COG0757	3-dehydroquinate dehydratase	146
641166117	166	38.93	16	164	3	139	5.0e-24	103	COG0511	Biotin carboxyl carrier protein	140
641166121	369	45.04	1	369	30	395	2.0e-107	383	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
641166122	453	32.89	1	443	1	441	3.0e-61	229	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
641166123	217	67.35	11	206	2	197	2.0e-81	295	COG0740	ATP-dependent protease ClpP, protease subunit	200
641166124	416	68.07	14	416	1	404	0.0e+00	658	COG1219	ATP-dependent protease Clp, ATPase subunit	408
641166131	467	37.17	4	298	59	353	1.0e-63	237	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
641166134	449	20.48	11	444	34	489	1.0e-27	117	COG0833	Amino acid permease	541
641166136	228	32.29	23	211	14	194	7.0e-22	97.4	COG3145	Alkylated DNA repair dioxygenase AlkB	194
641166137	785	26.85	327	689	13	399	2.0e-24	108	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
641166138	672	24.53	283	540	95	336	2.0e-24	108	COG0642	Signal transduction histidine kinase	336
641166143	330	21	11	201	4	192	2.0e-07	50.6	COG1525	Endonuclease YncB, thermonuclease family	192
641166147	216	27.33	6	166	2	162	9.0e-09	53.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641166150	185	32.16	7	176	14	180	2.0e-19	89	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641166156	569	32.57	52	569	22	488	3.0e-81	296	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
641166163	345	21.04	9	298	37	358	8.0e-15	74.8	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
641166167	351	25.12	90	293	15	225	5.0e-17	82.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641166169	209	33.56	63	205	38	182	5.0e-19	87.6	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
641166176	366	39.63	48	364	4	320	8.0e-64	237	COG0142	Geranylgeranyl pyrophosphate synthase	322
641166177	287	32.1	30	271	13	238	4.0e-50	191	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
641166178	207	38.65	3	206	1	189	2.0e-49	188	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
641166180	393	43.24	3	368	1	369	3.0e-104	372	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
641166181	684	30.04	20	290	9	246	7.0e-26	112	COG1427	Predicted periplasmic solute-binding protein	252
641166181	684	42.19	324	682	2	364	3.0e-102	366	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
641166187	1003	25.51	39	360	2	289	3.0e-31	131	COG0515	Serine/threonine protein kinase	384
641166188	294	43.11	127	291	13	178	7.0e-38	151	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
641166189	302	28.72	10	273	5	280	6.0e-25	108	COG4759	Uncharacterized protein	316
641166191	125	31.58	2	115	28	137	4.0e-13	66.8	COG0848	Biopolymer transport protein ExbD	137
641166194	240	34.72	19	232	1	207	2.0e-33	135	COG0811	Biopolymer transport protein ExbB/TolQ	216
641166197	239	50.23	13	225	4	214	5.0e-69	254	COG2360	Leu/Phe-tRNA-protein transferase	221
641166202	270	23.14	11	259	20	239	2.0e-23	103	COG0121	Predicted glutamine amidotransferase	252
641166204	446	38.35	28	438	8	404	1.0e-79	290	COG1301	Na+/H+-dicarboxylate symporter	415
641166208	409	26.85	204	403	8	204	2.0e-15	76.9	COG2755	Lysophospholipase L1 or related esterase	216
641166211	283	46.59	1	275	6	276	2.0e-71	262	COG3220	Uncharacterized conserved protein, UPF0276 family	282
641166215	243	27.81	65	212	37	187	2.0e-18	86.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
641166217	458	23.19	17	455	23	458	1.0e-35	144	COG0277	FAD/FMN-containing dehydrogenase	459
641166222	386	35.66	8	378	8	380	3.0e-84	306	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
641166224	520	37.95	5	513	14	514	2.0e-117	416	COG1640	4-alpha-glucanotransferase	520
641166225	671	45.39	1	645	9	682	0.0e+00	667	COG1523	Pullulanase/glycogen debranching enzyme	697
641166226	747	56.39	107	746	1	628	0.0e+00	739	COG0296	1,4-alpha-glucan branching enzyme	628
641166227	803	45.91	2	801	14	749	0.0e+00	764	COG0058	Glucan phosphorylase	750
641166228	346	37.21	1	343	1	317	3.0e-64	239	COG0837	Glucokinase	320
641166231	1424	31.73	4	591	1	533	8.0e-79	289	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641166232	328	20.75	23	301	14	295	3.0e-20	92.9	COG3239	Fatty acid desaturase	343
641166234	574	22.82	17	346	2	284	3.0e-15	77.5	COG0644	Dehydrogenase (flavoprotein)	396
641166239	616	27.84	33	614	7	567	2.0e-81	296	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
641166240	595	69.69	182	593	16	433	0.0e+00	616	COG2224	Isocitrate lyase	433
641166251	164	39.13	47	138	1	92	5.0e-08	50.8	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641166253	415	33.41	5	414	2	391	3.0e-54	205	COG0183	Acetyl-CoA acetyltransferase	392
641166254	411	28.81	1	407	1	389	1.0e-48	187	COG0183	Acetyl-CoA acetyltransferase	392
641166255	486	38.56	13	477	21	490	2.0e-92	333	COG3670	Carotenoid cleavage dioxygenase or a related enzyme	490
641166259	388	39.09	261	370	3	112	6.0e-16	78.9	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641166260	416	34.98	10	410	25	411	2.0e-53	203	COG2124	Cytochrome P450	411
641166262	336	54.46	2	335	1	334	9.0e-121	426	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
641166263	392	37.42	3	308	1	292	4.0e-48	185	COG3138	Arginine/ornithine N-succinyltransferase beta subunit	336
641166264	696	51.99	1	696	5	697	0.0e+00	814	COG0480	Translation elongation factor EF-G, a GTPase	697
641166265	679	58.18	18	673	5	657	0.0e+00	904	COG0021	Transketolase	663
641166266	348	35.73	1	335	2	330	6.0e-60	224	COG0136	Aspartate-semialdehyde dehydrogenase	334
641166269	374	27.16	69	305	2	232	2.0e-19	90.6	COG0714	MoxR-like ATPase	329
641166271	237	29.41	3	237	1	234	4.0e-33	135	COG0412	Dienelactone hydrolase	236
641166272	313	48.74	1	311	17	329	9.0e-79	287	COG0205	6-phosphofructokinase	347
641166273	539	36.67	364	470	3	122	7.0e-09	56.1	COG0645	Predicted kinase	170
641166276	260	41.2	33	244	9	224	1.0e-48	187	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
641166278	211	27.14	11	205	4	201	4.0e-10	58.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641166282	129	39.2	4	128	2	126	2.0e-26	111	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
641166283	63	60.66	2	61	17	77	4.0e-11	59.5	COG0227	Ribosomal protein L28	77
641166284	630	29.47	262	547	16	316	1.0e-35	144	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
641166297	788	25.89	91	749	39	753	2.0e-82	300	COG4772	Outer membrane receptor for Fe3+-dicitrate	753
641166301	321	33.65	1	313	18	322	2.0e-55	209	COG0042	tRNA-dihydrouridine synthase	323
641166307	189	29.55	1	174	2	177	5.0e-17	80.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641166310	237	29.9	5	197	4	192	6.0e-31	127	COG0300	Short-chain dehydrogenase	265
641166312	407	26.41	5	340	51	338	1.0e-41	163	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
641166314	484	31.85	6	443	2	444	4.0e-42	166	COG0591	Na+/proline symporter	493
641166315	434	40.18	10	434	13	443	2.0e-99	356	COG0174	Glutamine synthetase	443
641166317	252	28.65	4	195	1	188	4.0e-15	75.2	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
641166318	244	25.36	4	210	43	244	2.0e-10	59.6	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
641166321	382	45.48	3	380	2	388	4.0e-94	338	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641166322	276	47.99	5	276	3	267	5.0e-75	274	COG0796	Glutamate racemase	269
641166330	357	29.11	65	353	89	365	5.0e-28	118	COG5276	Uncharacterized conserved protein	370
641166331	1206	30.13	90	384	2	287	3.0e-39	158	COG0515	Serine/threonine protein kinase	384
641166332	295	37.4	50	295	6	255	1.0e-39	157	COG0584	Glycerophosphoryl diester phosphodiesterase	257
641166360	711	26.87	67	266	69	267	2.0e-12	68.4	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
641166365	215	36.87	37	215	4	179	1.0e-24	106	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641166366	1908	25.06	299	1107	2	750	3.0e-66	248	COG3899	Predicted ATPase	849
641166366	1908	27.69	7	293	1	304	7.0e-34	141	COG0515	Serine/threonine protein kinase	384
641166367	512	31.54	247	506	1	242	1.0e-31	131	COG1587	Uroporphyrinogen-III synthase	248
641166367	512	47.72	1	241	9	244	1.0e-64	241	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
641166374	556	32.71	8	271	24	279	5.0e-37	149	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
641166375	254	36.07	6	248	2	245	3.0e-57	215	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
641166376	261	39.3	4	255	42	296	2.0e-52	199	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
641166378	807	16.64	130	774	43	736	2.0e-10	61.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
641166379	238	24.59	1	237	2	244	8.0e-08	50.9	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
641166384	267	20.38	1	258	2	250	5.0e-09	55.2	COG4137	ABC-type uncharacterized transport system, permease component	265
641166385	457	39.28	1	443	1	414	4.0e-104	371	COG0373	Glutamyl-tRNA reductase	414
641166387	838	28.12	73	364	2	282	4.0e-38	153	COG0515	Serine/threonine protein kinase	384
641166388	307	26.56	80	271	1	180	4.0e-07	49.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641166394	546	19.79	344	521	38	222	4.0e-09	56.8	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
641166395	164	40.25	1	158	1	158	2.0e-31	128	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
641166396	395	42.79	4	393	1	388	3.0e-87	315	COG0183	Acetyl-CoA acetyltransferase	392
641166397	286	51.75	2	286	1	286	2.0e-92	332	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
641166398	266	43.73	1	261	1	256	3.0e-51	195	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641166399	382	48.59	1	382	1	391	2.0e-98	352	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641166401	383	46.82	1	383	1	392	2.0e-89	322	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641166409	280	24.78	67	269	6	229	1.0e-19	90.3	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
641166410	932	18.59	177	777	14	485	3.0e-09	58	COG3349	Uncharacterized conserved protein, contains NAD-binding domain and a Fe-S cluster	485
641166412	394	30.03	17	365	1	300	8.0e-48	184	COG0142	Geranylgeranyl pyrophosphate synthase	322
641166419	428	24.55	85	406	60	339	2.0e-08	53.9	COG4427	Uncharacterized protein	350
641166420	351	27.3	47	350	79	393	1.0e-40	160	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
641166421	105	52.75	11	101	10	100	7.0e-24	101	COG3695	Alkylated DNA nucleotide flippase Atl1, participates in nucleotide excision repair, Ada-like DNA-binding domain	103
641166424	260	31.25	10	217	2	201	4.0e-36	145	COG2384	tRNA A22 N-methylase	226
641166425	179	58.89	1	179	1	180	5.0e-75	273	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
641166427	706	33.96	35	705	14	667	0.0e+00	487	COG0272	NAD-dependent DNA ligase	667
641166429	728	24.94	148	514	70	427	5.0e-25	110	COG5184	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	476
641166431	317	34.36	11	317	4	329	1.0e-52	200	COG0240	Glycerol-3-phosphate dehydrogenase	329
641166433	228	38.51	65	223	2	154	6.0e-35	141	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
641166435	251	38.55	1	245	3	250	1.0e-45	176	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641166439	339	27.16	2	335	8	297	2.0e-24	106	COG1597	Diacylglycerol kinase family enzyme	301
641166450	417	28.03	10	405	1	391	3.0e-31	129	COG2814	Predicted arabinose efflux permease, MFS family	394
641166453	466	26.49	9	399	7	402	4.0e-46	179	COG3464	Transposase	402
641166454	494	48.18	162	490	1	330	4.0e-96	345	COG3800	Predicted transcriptional regulator	332
641166455	533	44.83	1	533	7	541	0.0e+00	511	COG2225	Malate synthase	545
641166456	1403	37.67	405	1244	4	832	0.0e+00	540	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
641166456	1403	40.91	48	374	2	326	8.0e-59	223	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
641166460	185	32.39	11	182	7	179	2.0e-14	72.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641166465	253	26.52	1	181	11	180	9.0e-14	70.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641166466	315	32.15	4	303	3	307	2.0e-49	189	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
641166470	512	48.32	3	415	1	409	7.0e-110	391	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
641166471	476	55.44	12	476	2	423	0.0e+00	589	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
641166472	211	49.01	1	201	1	191	9.0e-63	233	COG0066	3-isopropylmalate dehydratase small subunit	191
641166473	361	50.28	2	358	1	345	4.0e-111	394	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
641166478	316	28.43	113	208	2	101	2.0e-11	63.3	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
641166478	316	36.73	223	316	13	110	2.0e-12	67.3	COG0607	Rhodanese-related sulfurtransferase	110
641166478	316	48	7	105	2	101	3.0e-30	126	COG0278	Glutaredoxin-related protein	105
641166485	83	64.56	2	79	1	79	3.0e-24	103	COG0228	Ribosomal protein S16	87
641166486	82	60.53	7	82	1	76	7.0e-18	82.1	COG1837	Predicted RNA-binding protein YlqC, contains KH domain, UPF0109 family	76
641166487	186	28.34	1	184	1	174	2.0e-22	99.1	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
641166488	457	44.79	7	265	1	239	6.0e-78	285	COG0336	tRNA G37 N-methylase TrmD	240
641166489	160	60.19	10	117	7	114	7.0e-33	133	COG0335	Ribosomal protein L19	115
641166490	125	45.3	10	125	1	112	1.0e-21	95.3	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
641166499	310	18.78	20	214	15	197	9.0e-08	51.5	COG3063	Tfp pilus assembly protein PilF	250
641166502	185	42.19	1	128	4	131	6.0e-34	137	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
641166504	324	57.38	10	311	3	299	4.0e-109	387	COG0031	Cysteine synthase	300
641166505	271	39.3	3	202	32	221	3.0e-37	148	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
641166506	91	35.56	1	90	1	84	3.0e-10	56.9	COG1977	Molybdopterin converting factor, small subunit	84
641166507	342	44.88	35	331	3	298	6.0e-90	324	COG0031	Cysteine synthase	300
641166508	154	28.78	8	143	4	123	9.0e-10	56.3	COG1310	Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif	134
641166509	196	28.88	17	196	1	185	6.0e-23	100	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
641166511	170	18.03	1	169	1	182	6.0e-07	47.3	COG2952	Uncharacterized protein	183
641166516	408	36.63	9	408	10	408	9.0e-60	224	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
641166518	178	41.04	19	151	4	137	1.0e-25	109	COG3837	Uncharacterized conserved protein, cupin superfamily	161
641166519	324	24.21	12	324	21	322	7.0e-23	101	COG1612	Heme A synthase	323
641166524	201	21.94	1	189	21	257	1.0e-08	53.3	COG1192	Cellulose biosynthesis protein BcsQ	259
641166525	242	27.27	6	240	4	251	5.0e-28	118	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641166526	166	21.01	12	128	6	116	6.0e-08	50.7	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
641166531	866	38.19	209	639	20	442	5.0e-71	263	COG0038	H+/Cl- antiporter ClcA	443
641166534	392	45.57	11	389	35	398	3.0e-98	352	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
641166535	164	21.95	22	142	6	127	2.0e-06	45.7	COG0526	Thiol-disulfide isomerase or thioredoxin	127
641166539	292	30.63	18	287	1	260	4.0e-31	128	COG0575	CDP-diglyceride synthetase	265
641166540	274	51.49	2	236	10	243	4.0e-76	277	COG0020	Undecaprenyl pyrophosphate synthase	245
641166542	286	39.82	1	226	1	225	3.0e-30	125	COG1842	Phage shock protein A	225
641166544	172	27.56	2	128	1	126	2.0e-10	58.8	COG0645	Predicted kinase	170
641166550	996	28.34	79	374	2	278	1.0e-29	125	COG0515	Serine/threonine protein kinase	384
641166551	322	53.42	17	306	14	305	6.0e-110	390	COG0320	Lipoate synthase	306
641166553	995	21.43	725	960	2	220	3.0e-17	84.7	COG5011	Uncharacterized conserved protein, DUF2344 family	228
641166553	995	25.34	47	546	4	472	3.0e-44	174	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
641166559	685	28.88	32	253	9	235	1.0e-23	105	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
641166559	685	33.33	396	597	7	206	2.0e-26	114	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641166562	248	45.56	1	244	8	230	4.0e-51	194	COG0689	Ribonuclease PH	230
641166563	232	36.64	1	232	1	194	7.0e-42	163	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
641166569	1055	26.12	6	1016	1	1008	0.0e+00	582	COG0841	Multidrug efflux pump subunit AcrB	1009
641166570	382	24.6	66	270	54	304	9.0e-16	78.5	COG1566	Multidrug resistance efflux pump	352
641166571	530	22.32	41	366	2	287	3.0e-34	140	COG0515	Serine/threonine protein kinase	384
641166572	533	28.83	29	485	13	482	2.0e-99	356	COG0069	Glutamate synthase domain 2	485
641166574	466	51.24	180	462	1	262	4.0e-91	328	COG1760	L-serine deaminase	262
641166578	350	29.5	123	349	34	310	1.0e-28	120	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641166579	919	23.28	15	298	3	279	1.0e-32	135	COG0515	Serine/threonine protein kinase	384
641166581	788	32.35	39	424	112	481	5.0e-44	173	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
641166584	450	22.53	21	411	56	402	2.0e-24	107	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
641166588	377	28.06	112	353	45	285	5.0e-20	92.6	COG4974	Site-specific recombinase XerD	300
641166590	388	29.48	4	332	27	332	1.0e-35	144	COG3328	Transposase (or an inactivated derivative)	379
641166591	415	26.73	9	399	7	402	7.0e-44	171	COG3464	Transposase	402
641166596	567	38.89	9	426	5	405	1.0e-73	270	COG4402	Uncharacterized protein	457
641166598	255	28.12	5	192	12	178	8.0e-13	67.7	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
641166599	476	36.5	4	475	2	446	2.0e-83	303	COG2031	Short chain fatty acids transporter	446
641166602	145	32.87	1	143	5	137	3.0e-22	98	COG0824	Acyl-CoA thioesterase FadM	137
641166603	263	40.84	1	260	4	257	2.0e-47	182	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641166605	113	38.24	1	100	1	100	9.0e-13	65.5	COG0633	Ferredoxin	102
641166606	528	48.98	2	483	101	579	8.0e-120	424	COG0443	Molecular chaperone DnaK (HSP70)	579
641166609	183	25	20	172	2	157	2.0e-08	52.3	COG1076	DnaJ-domain-containing proteins 1	174
641166610	148	45.79	41	147	5	109	7.0e-28	116	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
641166611	126	49.66	1	126	5	147	3.0e-36	143	COG0822	NifU homolog involved in Fe-S cluster formation	150
641166612	406	58.97	5	390	1	386	0.0e+00	543	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
641166613	211	33.62	47	161	1	114	2.0e-16	79.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
641166615	301	28.4	10	171	4	165	3.0e-07	49.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641166628	516	22.73	35	331	26	320	3.0e-11	63.8	COG3299	Uncharacterized phage protein gp47/JayE	353
641166636	274	25.13	60	243	5	180	3.0e-09	56.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641166638	422	30.73	6	420	18	411	1.0e-51	197	COG2124	Cytochrome P450	411
641166639	205	32.6	3	179	2	182	5.0e-19	87.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641166640	718	51.76	10	717	5	682	0.0e+00	774	COG1770	Protease II	682
641166641	210	21.43	79	204	27	140	2.0e-06	46.2	COG0511	Biotin carboxyl carrier protein	140
641166648	187	26.67	3	182	19	190	1.0e-12	66.5	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
641166659	300	37.74	1	299	7	309	1.0e-52	200	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
641166660	96	33.68	4	91	17	111	6.0e-14	69.3	COG1733	DNA-binding transcriptional regulator, HxlR family	120
641166661	93	35.87	1	92	2	93	3.0e-19	86.9	COG5470	Uncharacterized conserved protein, DUF1330 family	96
641166664	472	28.62	40	297	2	288	3.0e-33	136	COG0515	Serine/threonine protein kinase	384
641166672	692	39.38	1	540	1	524	0.0e+00	488	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
641166674	269	49.62	1	260	1	251	8.0e-65	240	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
641166675	279	28.19	129	277	30	157	4.0e-12	65.4	COG3236	Predicted NAD-dependent protein-ADP-ribosyltransferase YbiA, DUF1768 family	162
641166677	569	22.89	55	334	17	266	5.0e-17	83.1	COG0863	DNA modification methylase	302
641166686	364	22.1	2	364	6	305	7.0e-23	101	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
641166687	213	26.5	1	197	2	200	2.0e-21	96.1	COG1011	FMN phosphatase YigB, HAD superfamily	229
641166690	374	25.45	92	349	21	285	6.0e-20	92.2	COG4974	Site-specific recombinase XerD	300
641166693	277	34.8	22	271	1	231	4.0e-24	105	COG2801	Transposase InsO and inactivated derivatives	232
641166695	163	26.28	21	160	21	176	4.0e-10	57.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641166697	448	26.83	67	319	2	285	2.0e-31	130	COG0515	Serine/threonine protein kinase	384
641166698	181	23.45	40	178	34	176	5.0e-07	47.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641166709	510	31.94	97	455	45	465	9.0e-48	185	COG3511	Phospholipase C	527
641166711	603	25.08	16	327	2	309	5.0e-37	149	COG0515	Serine/threonine protein kinase	384
641166713	159	30.19	53	158	2	107	1.0e-06	45.8	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
641166714	722	66.77	41	717	2	661	0.0e+00	1051	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
641166715	221	35.59	13	185	1	177	1.0e-18	86.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641166718	387	43.83	2	386	8	391	7.0e-82	298	COG0183	Acetyl-CoA acetyltransferase	392
641166719	426	31.31	36	420	1	376	1.0e-57	217	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
641166720	230	37.1	12	230	7	208	3.0e-30	125	COG0352	Thiamine monophosphate synthase	211
641166722	249	34.98	11	228	3	208	6.0e-37	147	COG0132	Dethiobiotin synthetase	223
641166723	368	41.69	2	359	9	382	1.0e-80	293	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
641166724	237	29.38	30	221	2	181	2.0e-21	96.5	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
641166730	280	28.24	1	255	2	255	2.0e-26	113	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
641166734	747	38.31	1	461	1	455	4.0e-111	395	COG2812	DNA polymerase III, gamma/tau subunits	515
641166735	107	44.66	1	102	2	103	8.0e-19	85.7	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
641166736	205	47.76	4	204	13	198	1.0e-60	225	COG0353	Recombinational DNA repair protein RecR	198
641166738	193	25.15	14	180	12	170	4.0e-12	65	COG2229	Signal recognition particle receptor subunit beta, a GTPase	187
641166742	211	31.07	32	206	51	223	1.0e-28	119	COG0220	tRNA G46 methylase TrmB	227
641166746	291	20.16	8	218	40	290	4.0e-08	52.3	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
641166750	592	28.11	184	576	83	447	3.0e-32	133	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
641166751	957	26.3	489	879	90	464	4.0e-43	170	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
641166752	262	40.61	2	261	29	287	1.0e-52	199	COG4242	Cyanophycinase and related exopeptidases	293
641166753	342	39.05	2	305	11	323	1.0e-58	220	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
641166758	406	20.67	9	405	3	402	1.0e-10	61.5	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
641166760	305	33.88	2	304	5	283	1.0e-43	170	COG3001	Fructosamine-3-kinase	286
641166761	166	37.25	10	161	4	139	2.0e-25	108	COG0394	Protein-tyrosine-phosphatase	139
641166762	922	51.52	7	922	1	877	0.0e+00	1102	COG0525	Valyl-tRNA synthetase	877
641166766	349	42.29	10	234	5	227	7.0e-56	211	COG1131	ABC-type multidrug transport system, ATPase component	293
641166767	775	22.38	44	308	5	270	1.0e-18	89	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
641166770	598	24.5	43	572	30	544	4.0e-24	106	COG0747	ABC-type transport system, periplasmic component	556
641166773	309	34.41	1	309	5	290	1.0e-39	157	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
641166774	214	53.04	10	190	4	182	3.0e-69	255	COG0194	Guanylate kinase	191
641166775	852	35.59	88	843	8	701	0.0e+00	554	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
641166779	173	49.1	5	168	5	171	5.0e-37	147	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
641166781	344	31.05	6	341	1	347	4.0e-62	231	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
641166784	166	32.14	1	160	10	177	4.0e-19	87.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641166790	1027	28.57	85	380	2	289	4.0e-34	141	COG0515	Serine/threonine protein kinase	384
641166791	209	29.48	1	166	5	177	5.0e-15	74.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641166797	391	38.35	13	142	38	170	8.0e-19	88.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641166805	1088	28.93	147	459	4	296	3.0e-59	224	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
641166805	1088	34.62	2	131	16	143	2.0e-26	115	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
641166805	1088	37.37	519	1088	3	548	0.0e+00	476	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
641166810	698	53.99	1	685	2	690	0.0e+00	852	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
641166811	147	53.9	7	147	10	146	5.0e-43	166	COG0756	dUTPase	148
641166813	323	31.05	32	304	8	247	7.0e-47	181	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
641166814	485	53.14	1	471	4	454	0.0e+00	604	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
641166815	354	60.34	110	346	1	235	2.0e-89	322	COG1186	Protein chain release factor B	239
641166816	767	33.43	435	765	115	408	2.0e-56	214	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
641166817	242	46.93	2	228	1	222	1.0e-74	272	COG1136	ABC-type lipoprotein export system, ATPase component	226
641166818	892	29.7	94	892	25	766	7.0e-128	452	COG4775	Outer membrane protein assembly factor BamA	766
641166819	166	27.27	2	164	8	170	2.0e-08	52.3	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
641166820	189	25.58	23	186	7	170	9.0e-09	53.4	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
641166821	160	41.78	3	145	4	147	7.0e-34	136	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
641166828	1043	37.4	118	477	43	392	1.0e-70	261	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
641166829	371	36.11	40	358	22	333	1.0e-53	204	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
641166830	296	37.41	10	291	5	271	5.0e-54	204	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
641166831	256	29.33	1	256	1	281	3.0e-23	102	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641166835	234	37.42	90	231	1	154	1.0e-22	100	COG0328	Ribonuclease HI	154
641166842	423	32.54	13	181	6	170	1.0e-17	84.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641166844	653	36.08	479	652	8	196	5.0e-30	126	COG0529	Adenylylsulfate kinase or related kinase	197
641166844	653	54.03	47	465	2	414	0.0e+00	553	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
641166845	301	34.19	1	301	11	261	2.0e-51	196	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
641166847	399	31.88	2	387	6	371	5.0e-59	221	COG0116	23S rRNA G2445 N2-methylase RlmL	381
641166849	469	31.88	1	206	34	234	1.0e-30	128	COG3208	Surfactin synthase thioesterase subunit	244
641166852	507	39.31	1	507	29	545	4.0e-114	405	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
641166853	430	39.36	33	424	5	402	1.0e-85	310	COG0004	Ammonia channel protein AmtB	409
641166854	1591	48.48	714	1203	9	481	0.0e+00	464	COG0069	Glutamate synthase domain 2	485
641166855	415	26.49	9	399	7	402	9.0e-44	171	COG3464	Transposase	402
641166863	351	23.3	24	351	2	316	2.0e-20	93.6	COG0714	MoxR-like ATPase	329
641166868	411	35.28	1	403	19	411	5.0e-68	251	COG2124	Cytochrome P450	411
641166872	549	25.26	150	511	106	462	7.0e-20	92.4	COG5184	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	476
641166876	271	33.22	4	265	2	293	6.0e-22	98.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
641166877	133	24.6	1	117	2	127	2.0e-06	44.6	COG4319	Ketosteroid isomerase homolog	137
641166878	503	31.93	1	100	17	135	3.0e-12	67.2	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
641166878	503	48.45	134	502	34	418	4.0e-120	425	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
641166886	279	32.39	1	278	13	292	9.0e-23	100	COG0583	DNA-binding transcriptional regulator, LysR family	297
641166890	213	37.93	2	202	35	234	2.0e-42	165	COG3208	Surfactin synthase thioesterase subunit	244
641166893	304	24.83	1	286	11	292	1.0e-23	103	COG0583	DNA-binding transcriptional regulator, LysR family	297
641166894	613	35.22	5	531	34	547	4.0e-110	392	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
641166900	469	29.8	7	151	4	146	1.0e-15	77.8	COG4276	Ligand-binding SRPBCC domain	153
641166900	469	41.81	175	467	1	295	1.0e-77	284	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
641166902	204	34.88	13	180	11	182	4.0e-17	81.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641166906	291	63.7	1	291	1	290	6.0e-114	403	COG0074	Succinyl-CoA synthetase, alpha subunit	293
641166907	398	56	1	398	1	385	0.0e+00	489	COG0045	Succinyl-CoA synthetase, beta subunit	387
641166909	399	36.39	1	398	2	396	2.0e-90	326	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
641166917	436	25.7	56	306	2	282	1.0e-29	124	COG0515	Serine/threonine protein kinase	384
641166920	231	24.19	171	231	11	72	1.0e-05	43.4	COG2442	Uncharacterized conserved protein, DUF433 family	79
641166923	415	26.73	9	399	7	402	2.0e-44	173	COG3464	Transposase	402
641166928	318	37.33	1	298	1	295	4.0e-63	235	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
641166929	534	27.54	7	508	2	472	9.0e-48	185	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641166932	776	36.56	25	579	27	550	2.0e-112	400	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
641166934	329	23.19	1	318	1	333	1.0e-18	87.4	COG5351	Uncharacterized protein	367
641166936	403	23.87	22	391	16	329	3.0e-10	60.1	COG5351	Uncharacterized protein	367
641166939	202	31.52	10	171	12	176	2.0e-19	89	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641166940	273	64	1	273	3	268	1.0e-111	396	COG0207	Thymidylate synthase	268
641166942	180	26.03	40	177	34	176	3.0e-07	48.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641166943	444	27.11	67	316	2	282	4.0e-31	129	COG0515	Serine/threonine protein kinase	384
641166952	2568	22.88	1905	2204	52	336	1.0e-05	47.2	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
641166959	218	34.36	28	189	3	161	2.0e-23	102	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
641166960	315	48.53	1	306	2	299	2.0e-91	329	COG0031	Cysteine synthase	300
641166965	768	24.35	10	764	1	727	6.0e-69	255	COG1033	Predicted exporter protein, RND superfamily	727
641166967	919	47.13	1	918	2	879	0.0e+00	950	COG0013	Alanyl-tRNA synthetase	879
641166972	370	50.28	5	356	5	353	2.0e-117	415	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
641166973	357	35.69	3	354	40	390	3.0e-68	252	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
641166974	571	48.43	61	568	3	498	0.0e+00	556	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
641166976	246	22.58	6	234	12	258	2.0e-25	109	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
641166984	256	38.4	1	244	42	284	6.0e-47	181	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
641166986	251	20.42	6	245	2	198	3.0e-09	55.8	COG2834	Outer membrane lipoprotein-sorting protein	211
641166992	409	36.28	5	407	4	447	2.0e-69	256	COG0527	Aspartokinase	447
641166993	527	34.58	96	520	75	483	6.0e-84	305	COG0260	Leucyl aminopeptidase	485
641166997	382	48.88	22	376	1	345	2.0e-105	375	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
641166999	1045	59.39	101	1045	4	933	0.0e+00	1407	COG0178	Excinuclease UvrABC ATPase subunit	935
641167000	216	31.08	23	170	14	146	3.0e-22	98.9	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
641167003	385	28.13	25	376	4	355	2.0e-44	173	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
641167008	707	32.6	272	699	151	588	2.0e-62	234	COG0465	ATP-dependent Zn proteases	596
641167017	363	54.23	2	344	8	346	3.0e-115	408	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641167021	735	28.43	53	336	3	308	2.0e-36	147	COG0515	Serine/threonine protein kinase	384
641167026	2197	41.82	894	2000	5	1047	0.0e+00	744	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
641167033	854	27.66	445	626	5	190	2.0e-14	74.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641167033	854	32.63	88	415	4	326	3.0e-47	184	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
641167038	217	23.81	42	175	13	155	4.0e-07	48.7	COG1225	Peroxiredoxin	157
641167040	328	18.36	1	321	2	364	1.0e-11	64.2	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
641167043	326	40.77	1	259	2	261	3.0e-64	239	COG1131	ABC-type multidrug transport system, ATPase component	293
641167046	1591	32.89	36	1586	34	1589	0.0e+00	914	COG2902	NAD-specific glutamate dehydrogenase	1592
641167047	455	31.08	45	437	19	375	9.0e-58	218	COG0006	Xaa-Pro aminopeptidase	384
641167048	186	37.5	31	157	7	132	1.0e-26	112	COG2343	Uncharacterized conserved protein, DUF427 family	132
641167050	326	29.74	57	324	31	296	1.0e-41	163	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
641167054	253	41.63	1	252	6	252	3.0e-59	221	COG0631	Serine/threonine protein phosphatase PrpC	262
641167055	438	37.5	3	258	1	251	6.0e-56	212	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
641167055	438	51.25	269	428	2	161	9.0e-44	171	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
641167056	378	60.21	8	293	1	279	7.0e-85	307	COG0468	RecA/RadA recombinase	279
641167057	553	25	4	380	6	357	3.0e-38	153	COG3119	Arylsulfatase A or related enzyme	475
641167060	98	32.67	1	98	20	118	9.0e-11	58.5	COG3255	Putative sterol carrier protein	134
641167062	285	53.54	1	251	1	253	3.0e-88	318	COG0024	Methionine aminopeptidase	255
641167063	338	27.56	28	246	3	248	3.0e-18	86.2	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
641167065	378	32.42	6	360	2	352	1.0e-56	213	COG5351	Uncharacterized protein	367
641167068	631	29.28	7	290	2	290	5.0e-33	136	COG0515	Serine/threonine protein kinase	384
641167071	379	31.51	10	373	2	325	6.0e-48	185	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
641167076	259	41.42	18	253	1	236	8.0e-51	193	COG3208	Surfactin synthase thioesterase subunit	244
641167078	294	28.57	12	277	9	280	4.0e-28	118	COG1792	Cell shape-determining protein MreC	284
641167079	344	67.95	8	341	3	338	8.0e-121	426	COG1077	Actin-like ATPase involved in cell morphogenesis	342
641167082	238	34.82	16	237	4	250	5.0e-42	164	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
641167083	204	21.7	5	199	3	211	1.0e-08	53.1	COG3295	Uncharacterized protein	213
641167085	309	35.16	45	299	8	228	1.0e-48	186	COG0274	Deoxyribose-phosphate aldolase	228
641167086	498	47.32	34	494	1	460	0.0e+00	464	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641167090	473	31.89	27	473	40	487	1.0e-68	254	COG3670	Carotenoid cleavage dioxygenase or a related enzyme	490
641167091	952	39.26	427	948	36	543	5.0e-102	366	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
641167095	592	45.07	254	582	11	340	8.0e-92	331	COG0552	Signal recognition particle GTPase	340
641167098	570	38.16	7	407	15	404	7.0e-75	275	COG4402	Uncharacterized protein	457
641167101	340	51.49	1	335	1	331	8.0e-109	387	COG3588	Fructose-bisphosphate aldolase class 1	332
641167104	359	21.31	153	359	90	309	2.0e-12	66.7	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641167105	887	33.99	540	845	27	312	8.0e-50	192	COG0616	Periplasmic serine protease, ClpP class	317
641167108	563	26.54	23	230	30	240	2.0e-16	80.9	COG0704	Phosphate uptake regulator	240
641167109	303	27.4	13	297	36	318	5.0e-27	115	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
641167111	422	26.26	53	406	7	298	8.0e-19	88.8	COG0391	Archaeal 2-phospho-L-lactate transferase/Bacterial gluconeogenesis factor, CofD/UPF0052 family	323
641167113	3091	49.43	56	917	2	856	0.0e+00	739	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
641167114	3382	36.92	161	814	1	642	1.0e-103	373	COG1020	Non-ribosomal peptide synthetase component F	642
641167117	361	24.65	6	345	26	365	4.0e-30	125	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
641167129	246	35.29	19	205	4	176	2.0e-22	99.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641167130	174	31.14	5	171	14	150	4.0e-24	104	COG0779	Ribosome maturation factor RimP	153
641167131	461	55.15	184	376	1	188	6.0e-46	178	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
641167132	156	30.85	1	94	6	95	3.0e-13	68.1	COG2740	Predicted RNA-binding protein YlxR, DUF448 family	95
641167133	936	53.33	435	936	2	508	0.0e+00	541	COG0532	Translation initiation factor IF-2, a GTPase	509
641167134	153	47.5	1	119	3	118	4.0e-24	104	COG0858	Ribosome-binding factor A	118
641167139	233	36.26	9	176	19	188	3.0e-30	125	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
641167142	288	20.31	22	259	45	274	5.0e-08	51.9	COG3386	Sugar lactone lactonase YvrE	307
641167149	302	27.95	1	292	1	292	7.0e-21	94.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
641167152	928	32.64	504	871	61	441	1.0e-44	175	COG2319	WD40 repeat	466
641167155	387	27.86	16	386	10	379	6.0e-43	168	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
641167157	282	32.76	155	270	2	117	4.0e-12	65.8	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641167163	206	31.61	7	175	1	174	4.0e-11	61.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641167176	287	30.83	13	262	5	246	2.0e-36	146	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
641167177	144	43.88	1	138	1	137	5.0e-36	143	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
641167178	95	65.48	1	84	3	86	3.0e-29	119	COG3492	Uncharacterized protein	104
641167185	359	29.15	2	336	29	368	3.0e-33	135	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
641167186	849	26.2	1	434	59	434	5.0e-32	133	COG2319	WD40 repeat	466
641167189	98	50.88	23	79	13	69	1.0e-07	48	COG1722	Exonuclease VII small subunit	81
641167190	166	47.69	21	150	12	140	2.0e-27	115	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
641167192	347	21.89	27	286	21	275	3.0e-17	82.6	COG0682	Prolipoprotein diacylglyceryltransferase	287
641167199	200	35.71	81	192	3	114	8.0e-10	57.3	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641167200	383	32.47	5	379	24	402	1.0e-50	194	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
641167204	847	36.99	1	620	101	743	8.0e-123	435	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
641167211	1521	26.69	1069	1373	66	329	1.0e-25	113	COG0642	Signal transduction histidine kinase	336
641167212	139	40.52	11	126	9	123	1.0e-18	85.8	COG4270	Uncharacterized membrane protein	131
641167213	275	25.28	21	268	62	310	2.0e-19	89.8	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641167216	293	31.67	2	293	12	303	1.0e-36	147	COG0258	5'-3' exonuclease	310
641167219	280	43.87	4	270	7	274	3.0e-62	231	COG4295	Uncharacterized protein	285
641167220	584	25.57	113	451	1	336	2.0e-30	127	COG0642	Signal transduction histidine kinase	336
641167222	461	23.42	90	451	28	395	4.0e-18	86.6	COG2312	Erythromycin esterase homolog	405
641167224	290	55.02	1	289	1	288	1.0e-100	359	COG1946	Acyl-CoA thioesterase	289
641167226	541	42.55	25	492	16	472	5.0e-115	408	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641167228	2629	27.71	2051	2270	7	236	4.0e-12	69.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641167228	2629	40.96	937	2022	1	1054	0.0e+00	742	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
641167230	441	41.37	117	439	126	461	2.0e-82	299	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641167231	281	41.82	1	273	11	268	5.0e-54	204	COG0294	Dihydropteroate synthase	274
641167232	300	37.12	10	233	12	236	7.0e-34	138	COG1624	Diadenylate cyclase (c-di-AMP synthetase), DisA_N domain	247
641167234	453	42.52	1	453	3	462	4.0e-106	378	COG1109	Phosphomannomutase	464
641167235	498	36.49	5	214	1	203	9.0e-31	128	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
641167235	498	37.23	231	498	9	257	2.0e-34	140	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
641167237	199	37.34	31	188	20	172	5.0e-20	91.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641167238	486	44.01	1	480	3	464	9.0e-101	360	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641167239	349	19.82	26	327	65	384	4.0e-11	62.6	COG2311	Uncharacterized membrane protein YeiB	394
641167240	554	21.25	3	272	23	314	4.0e-19	89.8	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641167240	554	30.04	329	546	24	250	2.0e-21	97.5	COG0388	Predicted amidohydrolase	274
641167242	1287	34.02	500	831	4	326	2.0e-45	179	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
641167243	1042	45.97	31	1036	4	994	0.0e+00	789	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
641167246	384	22.83	123	377	24	260	2.0e-12	66.9	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
641167252	96	30.77	8	96	4	90	2.0e-06	44.5	COG2921	Putative lipoic acid-binding regulatory protein	90
641167253	397	29.79	43	348	26	354	1.0e-18	87.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
641167254	1132	30.55	25	1123	9	1006	0.0e+00	646	COG0841	Multidrug efflux pump subunit AcrB	1009
641167259	814	44.59	113	800	8	676	0.0e+00	676	COG1200	RecG-like helicase	677
641167261	366	32.21	5	352	4	358	2.0e-56	213	COG5351	Uncharacterized protein	367
641167264	751	34.59	14	561	18	550	1.0e-101	364	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
641167266	223	34.82	112	223	3	114	8.0e-11	60.8	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641167267	382	27.03	6	376	13	375	1.0e-41	164	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
641167268	320	43.89	1	316	6	318	2.0e-50	192	COG0530	Ca2+/Na+ antiporter	320
641167269	406	24.41	15	307	2	291	1.0e-21	97.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
641167271	287	23.86	4	287	26	292	2.0e-21	96.3	COG3239	Fatty acid desaturase	343
641167273	308	21.62	7	301	6	246	1.0e-18	87.3	COG1018	Ferredoxin-NADP reductase	266
641167284	300	25.19	40	300	19	280	1.0e-17	84.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641167285	641	30.05	1	636	245	857	6.0e-76	279	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
641167286	325	45.31	19	322	21	318	7.0e-74	271	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
641167289	128	35.43	1	127	1	123	5.0e-13	66.8	COG3686	Uncharacterized conserved protein, MAPEG superfamily	125
641167305	520	40.58	3	204	1	196	2.0e-46	180	COG0518	GMP synthase - Glutamine amidotransferase domain	198
641167305	520	66.24	207	520	1	310	0.0e+00	516	COG0519	GMP synthase, PP-ATPase domain/subunit	315
641167306	493	30.91	262	481	1	169	2.0e-33	137	COG0516	IMP dehydrogenase/GMP reductase	170
641167306	493	40.17	97	207	5	117	2.0e-14	74	COG0517	CBS domain	117
641167316	306	40.13	150	304	3	154	1.0e-27	116	COG3449	DNA gyrase inhibitor GyrI	154
641167316	306	46.36	8	117	19	127	7.0e-22	98	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641167321	803	31.28	20	223	9	215	4.0e-12	67.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641167324	526	30.48	87	359	2	281	1.0e-43	171	COG0515	Serine/threonine protein kinase	384
641167327	172	26.42	4	158	16	174	7.0e-14	70.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641167336	303	22.88	1	303	3	270	3.0e-13	69.6	COG0492	Thioredoxin reductase	305
