gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
644850383	464	56.48	6	460	1	408	0.0e+00	512	COG0593	Chromosomal replication initiation ATPase DnaA	408
644850384	366	44.14	1	366	1	364	3.0e-108	385	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
644850385	361	43.25	1	356	1	362	6.0e-108	384	COG1195	Recombinational DNA repair ATPase RecF	363
644850386	803	65.05	1	556	2	555	0.0e+00	928	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
644850387	394	22.14	30	380	52	431	2.0e-13	70.6	COG2271	Sugar phosphate permease	448
644850389	680	60.94	1	680	8	683	0.0e+00	995	COG0339	Zn-dependent oligopeptidase	683
644850391	280	64.87	2	280	1	279	1.0e-120	425	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
644850392	304	49.18	1	304	2	291	1.0e-80	293	COG1234	Ribonuclease BN, tRNA processing enzyme	292
644850393	529	63.28	1	528	1	530	0.0e+00	734	COG4650	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain	531
644850395	407	37.33	14	407	6	432	1.0e-120	427	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
644850396	450	39.17	1	450	1	454	1.0e-124	440	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
644850397	471	32.91	6	392	1	389	4.0e-49	189	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
644850398	352	24.54	27	347	18	323	1.0e-45	177	COG2845	Uncharacterized protein	354
644850399	392	18.59	186	380	13	205	1.0e-05	44.5	COG2755	Lysophospholipase L1 or related esterase	216
644850401	156	37.5	1	152	4	154	8.0e-33	132	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644850402	373	25.27	8	367	1	362	1.0e-52	200	COG1932	Phosphoserine aminotransferase	365
644850404	146	35.34	23	138	8	123	4.0e-11	61.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
644850406	322	58.04	1	317	4	320	3.0e-121	428	COG0837	Glucokinase	320
644850407	295	27.21	5	294	2	288	2.0e-30	126	COG0583	DNA-binding transcriptional regulator, LysR family	297
644850408	339	36.23	16	337	15	326	1.0e-45	177	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
644850409	372	30.27	184	367	2	174	1.0e-15	77.5	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
644850410	346	27.14	13	326	6	334	9.0e-31	127	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
644850411	558	51.03	14	544	4	535	0.0e+00	600	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
644850412	286	44.4	9	283	4	280	2.0e-55	209	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644850413	313	43.22	3	309	2	315	4.0e-62	231	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644850414	547	25.54	15	547	17	554	1.0e-64	241	COG0747	ABC-type transport system, periplasmic component	556
644850416	418	78.37	1	416	1	416	0.0e+00	722	COG3977	Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase	417
644850418	93	39.78	1	93	1	92	3.0e-23	100	COG3309	Virulence-associated protein VapD (function unknown)	96
644850419	320	43.08	1	317	1	324	7.0e-96	344	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
644850420	151	22.54	1	125	13	154	3.0e-06	44.6	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
644850421	186	60.43	1	186	1	187	2.0e-81	295	COG2818	3-methyladenine DNA glycosylase Tag	188
644850422	268	29.37	1	262	2	251	2.0e-09	56.2	COG0730	Uncharacterized membrane protein YfcA	258
644850423	304	81.33	3	302	1	298	0.0e+00	574	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
644850424	694	55.6	1	694	1	690	0.0e+00	926	COG0751	Glycyl-tRNA synthetase, beta subunit	691
644850426	1197	39.72	1	556	1	553	0.0e+00	528	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
644850427	211	37.5	10	211	43	247	9.0e-45	173	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
644850428	239	29.05	9	210	51	254	4.0e-23	101	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
644850429	259	43.1	1	239	1	223	7.0e-65	240	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
644850430	270	33.2	12	270	9	257	2.0e-33	136	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
644850431	351	25.38	1	319	5	320	2.0e-26	113	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
644850433	635	74.89	1	467	1	470	0.0e+00	744	COG2213	Phosphotransferase system, mannitol-specific IIBC component	472
644850434	383	33.11	3	383	17	455	4.0e-88	318	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
644850435	201	66.67	25	201	1	173	5.0e-60	224	COG3722	DNA-binding transcriptional regulator, MltR family	174
644850436	628	37.18	238	602	19	408	1.0e-52	201	COG0840	Methyl-accepting chemotaxis protein	408
644850437	208	62.26	1	208	2	203	4.0e-77	280	COG0605	Superoxide dismutase	204
644850438	272	53.69	29	270	22	264	8.0e-84	303	COG1526	Formate dehydrogenase assembly factor FdhD	266
644850439	511	44.47	24	506	1	472	0.0e+00	509	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644850440	486	43.93	1	485	5	498	6.0e-129	454	COG1070	Sugar (pentulose or hexulose) kinase	502
644850441	439	78.26	1	437	2	438	0.0e+00	779	COG2115	Xylose isomerase	438
644850442	331	62.83	1	331	1	339	2.0e-118	418	COG4213	ABC-type xylose transport system, periplasmic component	341
644850443	513	51.28	1	504	5	500	0.0e+00	613	COG1129	ABC-type sugar transport system, ATPase component	500
644850444	394	57.63	20	394	15	394	1.0e-118	420	COG4214	ABC-type xylose transport system, permease component	394
644850445	409	23.51	18	278	72	329	3.0e-31	129	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644850446	191	32.42	1	168	1	182	9.0e-22	96.8	COG0693	Putative intracellular protease/amidase	188
644850447	92	45.05	1	91	1	89	8.0e-19	85.3	COG1937	DNA-binding transcriptional regulator, FrmR family	89
644850448	300	34.23	1	296	41	298	8.0e-52	197	COG2215	ABC-type nickel/cobalt efflux system, permease component RcnA	303
644850449	449	35.78	8	427	1	402	0.0e+00	468	COG0137	Argininosuccinate synthase	403
644850450	166	27.2	37	160	5	126	3.0e-10	58.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
644850451	288	23.72	58	272	71	278	9.0e-09	54.5	COG5006	Threonine/homoserine efflux transporter RhtA	292
644850452	316	47.54	1	305	1	305	3.0e-93	335	COG2313	Pseudouridine-5'-phosphate glycosidase (pseudoU degradation)	310
644850453	230	40.38	1	213	3	214	6.0e-44	171	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
644850454	1439	33.7	70	605	127	642	3.0e-96	347	COG1020	Non-ribosomal peptide synthetase component F	642
644850455	334	17.15	88	305	63	295	2.0e-06	47.1	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
644850458	452	20.7	20	439	16	442	1.0e-14	74.5	COG0534	Na+-driven multidrug efflux pump	455
644850460	187	35.64	44	144	22	121	2.0e-18	85.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644850461	235	48.42	4	222	1	220	1.0e-73	269	COG1136	ABC-type lipoprotein export system, ATPase component	226
644850463	466	43.62	1	464	1	457	2.0e-127	449	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644850469	378	23.69	21	361	26	380	5.0e-22	99.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644850472	377	25.79	73	369	67	379	3.0e-32	132	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644850474	510	25.42	1	504	9	531	3.0e-52	199	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644850475	519	24.27	27	516	36	534	1.0e-48	187	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644850477	527	31.73	7	511	13	525	6.0e-99	354	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644850479	440	32.32	19	408	12	394	3.0e-80	292	COG0019	Diaminopimelate decarboxylase	394
644850481	250	43.55	179	240	4	65	9.0e-11	60.8	COG2771	DNA-binding transcriptional regulator, CsgD family	65
644850482	212	35.23	1	191	1	193	1.0e-47	182	COG3916	N-acyl-L-homoserine lactone synthetase	209
644850484	256	57.48	1	253	1	251	5.0e-84	304	COG0149	Triosephosphate isomerase	251
644850486	141	31.62	1	131	5	117	8.0e-15	73	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
644850487	248	32.84	1	248	2	266	1.0e-47	183	COG1018	Ferredoxin-NADP reductase	266
644850488	336	67.98	1	331	1	330	0.0e+00	491	COG1494	Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase or related protein	332
644850489	503	68.94	3	501	2	499	0.0e+00	836	COG0554	Glycerol kinase	499
644850490	283	51.56	7	259	2	241	4.0e-57	215	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
644850491	80	82.28	1	79	1	79	3.0e-13	66.7	COG3074	Cell division protein ZapB, interacts with FtsZ	79
644850492	161	46.01	4	161	12	174	6.0e-45	173	COG0684	Regulator of RNase E activity RraA	210
644850493	305	47	7	305	5	300	4.0e-73	268	COG1575	1,4-dihydroxy-2-naphthoate octaprenyltransferase	303
644850494	443	76.13	1	443	1	444	0.0e+00	728	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
644850495	176	75.43	1	175	4	178	2.0e-76	277	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
644850496	279	41.99	1	279	18	264	3.0e-39	155	COG3087	Cell division protein FtsN	264
644850497	356	44.74	10	341	1	333	3.0e-92	332	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644850498	732	51.43	1	731	1	729	0.0e+00	888	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
644850499	71	58.11	1	71	1	74	3.0e-21	93.4	COG0254	Ribosomal protein L31	75
644850500	105	92.38	1	105	1	105	2.0e-52	196	COG3060	Transcriptional regulator of met regulon	105
644850501	386	49.1	6	384	9	396	2.0e-129	456	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
644850502	811	33.56	13	454	3	445	1.0e-101	365	COG0527	Aspartokinase	447
644850503	307	41.72	1	304	1	324	6.0e-63	234	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
644850504	224	17.24	10	212	6	198	1.0e-08	53.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644850506	298	49.48	11	294	3	291	8.0e-86	310	COG0685	5,10-methylenetetrahydrofolate reductase	291
644850507	243	67.66	2	163	1	165	4.0e-68	251	COG0678	Peroxiredoxin	165
644850508	305	33.89	1	299	1	297	2.0e-42	166	COG0583	DNA-binding transcriptional regulator, LysR family	297
644850509	468	39.91	8	460	4	454	0.0e+00	468	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
644850510	218	24.1	7	200	3	196	3.0e-07	48.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644850512	367	31.99	1	359	75	432	7.0e-83	301	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
644850513	631	43.97	4	631	2	608	0.0e+00	598	COG4206	Outer membrane cobalamin receptor protein	608
644850514	290	45.15	21	285	3	267	2.0e-84	305	COG0796	Glutamate racemase	269
644850522	275	28.67	1	267	1	284	2.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
644850523	112	80.36	1	112	1	112	6.0e-42	162	COG3085	Uncharacterized conserved protein YifE, UPF0438 family	112
644850524	508	60.49	15	499	1	490	0.0e+00	624	COG0606	Predicted ATPase with chaperone activity	490
644850525	403	26.4	5	390	4	389	3.0e-22	99.9	COG2814	Predicted arabinose efflux permease, MFS family	394
644850526	548	51.82	1	543	2	549	0.0e+00	644	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
644850527	85	60.47	1	85	1	86	2.0e-21	93.5	COG3978	Acetolactate synthase small subunit, contains ACT domain	86
644850528	308	44.56	5	296	1	284	2.0e-76	279	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
644850529	616	55.59	1	614	8	575	0.0e+00	802	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
644850530	514	52.59	9	351	1	347	7.0e-120	424	COG1171	Threonine dehydratase	347
644850531	246	22.71	5	225	4	226	3.0e-17	82.4	COG5587	Uncharacterized conserved protein, DUF2461 family	228
644850533	295	34.92	1	294	1	289	6.0e-40	158	COG0583	DNA-binding transcriptional regulator, LysR family	297
644850534	492	41.33	19	362	1	338	4.0e-124	438	COG0059	Ketol-acid reductoisomerase	338
644850536	499	47.48	4	484	1	493	2.0e-97	349	COG0591	Na+/proline symporter	493
644850537	1325	66.08	530	1325	1	769	0.0e+00	1039	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
644850539	674	47.35	1	650	1	655	0.0e+00	611	COG0210	Superfamily I DNA or RNA helicase	655
644850540	602	26.39	39	537	4	453	6.0e-59	222	COG5434	Polygalacturonase	542
644850542	500	41.84	9	489	4	492	3.0e-128	452	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
644850543	428	40.88	1	428	21	446	8.0e-111	394	COG0513	Superfamily II DNA and RNA helicase	513
644850545	419	79	1	419	4	421	0.0e+00	732	COG1158	Transcription termination factor Rho	422
644850546	353	28.3	1	308	4	311	2.0e-37	150	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
644850547	341	37.76	6	341	9	341	3.0e-72	266	COG3765	LPS O-antigen chain length determinant protein, WzzB/FepE family	347
644850548	376	57.45	1	373	4	372	0.0e+00	490	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
644850549	420	48.47	5	420	11	424	0.0e+00	509	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
644850551	376	43.65	1	376	5	372	5.0e-110	391	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
644850552	416	23.02	1	414	6	414	4.0e-10	59.7	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
644850555	244	41.7	1	244	4	249	5.0e-66	244	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
644850556	464	50.77	2	458	3	457	0.0e+00	513	COG1113	L-asparagine transporter and related permeases	462
644850561	112	33.65	6	108	8	109	1.0e-14	71.6	COG4538	Uncharacterized protein	112
644850562	454	41.24	15	445	5	438	2.0e-120	426	COG0015	Adenylosuccinate lyase	438
644850564	259	31.84	3	255	2	267	1.0e-33	136	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644850565	227	44.76	16	225	15	222	8.0e-50	190	COG0765	ABC-type amino acid transport system, permease component	222
644850566	253	58.26	1	242	2	239	1.0e-95	342	COG1126	ABC-type polar amino acid transport system, ATPase component	240
644850567	386	44.21	10	379	10	389	2.0e-107	382	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
644850568	398	57.25	1	393	1	393	1.0e-118	420	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
644850569	377	52.51	1	377	1	375	3.0e-86	312	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
644850570	246	33.06	1	245	2	241	5.0e-45	174	COG1587	Uroporphyrinogen-III synthase	248
644850571	322	63.37	16	317	4	306	5.0e-122	430	COG0181	Porphobilinogen deaminase	307
644850572	852	76.9	1	850	1	853	0.0e+00	1320	COG3072	Adenylate cyclase	853
644850573	106	60.95	1	105	1	105	2.0e-39	153	COG1965	Iron-binding protein CyaY, frataxin homolog	106
644850574	60	40.38	7	58	1	52	6.0e-07	45.8	COG5567	Predicted small periplasmic lipoprotein YifL (function unknown0	58
644850575	274	55.47	1	274	1	272	9.0e-104	369	COG0253	Diaminopimelate epimerase	272
644850576	233	57.66	12	231	3	218	3.0e-57	215	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
644850577	302	72.54	6	300	5	299	5.0e-128	450	COG4973	Site-specific recombinase XerC	299
644850578	238	26.58	7	238	1	226	3.0e-26	112	COG1011	FMN phosphatase YigB, HAD superfamily	229
644850579	720	46.36	8	653	1	655	0.0e+00	619	COG0210	Superfamily I DNA or RNA helicase	655
644850580	316	36.22	1	316	4	322	2.0e-66	246	COG0598	Mg2+ and Co2+ transporter CorA	322
644850581	352	47.56	1	347	2	350	2.0e-64	239	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
644850582	306	61.25	7	295	6	293	3.0e-86	312	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
644850583	156	23.84	6	155	2	136	3.0e-14	71.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
644850584	289	58.61	5	289	16	317	4.0e-99	354	COG2829	Outer membrane phospholipase A	317
644850585	599	58.99	3	593	5	587	0.0e+00	780	COG0514	Superfamily II DNA helicase RecQ	590
644850586	207	32.86	1	207	2	207	2.0e-27	115	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644850587	206	38.16	1	204	1	207	4.0e-33	135	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644850588	330	33.55	22	329	1	294	6.0e-55	207	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
644850589	265	35.07	1	265	2	262	7.0e-56	210	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
644850590	360	38.58	26	349	5	254	1.0e-46	180	COG0584	Glycerophosphoryl diester phosphodiesterase	257
644850591	449	53.11	1	447	1	446	0.0e+00	537	COG2271	Sugar phosphate permease	448
644850592	547	39.66	9	528	12	532	0.0e+00	476	COG0578	Glycerol-3-phosphate dehydrogenase	532
644850593	416	51.2	1	414	1	416	5.0e-124	437	COG3075	Anaerobic glycerol-3-phosphate dehydrogenase	421
644850594	400	31.37	2	398	1	385	1.0e-65	244	COG0247	Fe-S oxidoreductase	388
644850595	232	41.06	1	231	1	245	7.0e-57	214	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
644850598	287	20.71	19	286	43	314	2.0e-18	86.8	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
644850601	90	26.04	1	90	1	96	3.0e-08	50.4	COG0633	Ferredoxin	102
644850603	270	18.61	12	269	14	277	2.0e-10	60	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
644850604	250	30.99	1	240	6	245	6.0e-36	144	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
644850605	503	23.2	35	458	50	460	6.0e-30	125	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
644850607	332	34.95	7	332	1	329	7.0e-75	274	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644850608	172	61.49	9	169	1	160	6.0e-63	233	COG3265	Gluconate kinase	161
644850609	438	55.56	1	438	2	442	5.0e-104	371	COG2610	H+/gluconate symporter or related permease	442
644850610	197	44.44	1	196	4	201	7.0e-36	143	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
644850611	366	32.61	1	366	1	334	1.0e-98	353	COG0136	Aspartate-semialdehyde dehydrogenase	334
644850612	139	38.35	1	133	4	136	6.0e-29	119	COG0864	Metal-responsive transcriptional regulator, contains CopG/Arc/MetJ DNA-binding domain	136
644850613	70	67.69	4	68	1	65	2.0e-24	103	COG1278	Cold shock protein, CspA family	67
644850614	561	58.96	4	559	1	552	0.0e+00	697	COG3275	Sensor histidine kinase, LytS/YehU family	557
644850615	727	59.9	100	723	1	626	0.0e+00	804	COG0296	1,4-alpha-glucan branching enzyme	628
644850616	656	50.07	1	655	9	691	0.0e+00	752	COG1523	Pullulanase/glycogen debranching enzyme	697
644850617	428	53.55	15	423	1	386	0.0e+00	544	COG0448	ADP-glucose pyrophosphorylase	393
644850618	477	53.29	1	476	1	478	0.0e+00	534	COG0297	Glycogen synthase	487
644850619	815	51.17	9	812	1	750	0.0e+00	927	COG0058	Glucan phosphorylase	750
644850620	499	49.02	1	498	10	518	0.0e+00	571	COG0578	Glycerol-3-phosphate dehydrogenase	532
644850621	106	27.18	1	99	1	103	2.0e-15	74.2	COG0607	Rhodanese-related sulfurtransferase	110
644850622	280	31.66	99	278	15	213	4.0e-22	98.6	COG0705	Membrane associated serine protease, rhomboid family	228
644850623	252	41.67	1	252	1	252	1.0e-75	276	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
644850624	805	45.43	8	801	7	746	0.0e+00	783	COG0058	Glucan phosphorylase	750
644850625	717	40.57	128	686	1	516	0.0e+00	489	COG1640	4-alpha-glucanotransferase	520
644850626	191	50.54	98	189	1	93	2.0e-27	115	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
644850627	239	42.24	8	239	14	225	9.0e-49	187	COG1040	Predicted amidophosphoribosyltransferases	225
644850628	261	27.21	3	256	11	282	1.0e-22	100	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644850629	402	50.64	10	400	1	379	2.0e-110	392	COG3328	Transposase (or an inactivated derivative)	379
644850631	780	61.75	1	780	6	780	0.0e+00	1060	COG2183	Transcriptional accessory protein Tex/SPT6	780
644850633	666	19.29	55	630	43	604	9.0e-34	139	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
644850634	160	43.05	6	155	1	150	9.0e-37	146	COG0782	Transcription elongation factor, GreA/GreB family	151
644850635	239	43.35	5	236	1	229	4.0e-63	234	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644850636	470	30.91	142	444	22	335	2.0e-37	150	COG0642	Signal transduction histidine kinase	336
644850637	539	65.36	7	539	6	529	0.0e+00	837	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
644850639	290	47.9	1	280	1	286	3.0e-98	351	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
644850640	137	59.57	10	103	6	99	2.0e-25	108	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
644850641	234	22.84	7	226	1	229	2.0e-21	96.1	COG1011	FMN phosphatase YigB, HAD superfamily	229
644850643	190	19.75	36	177	1	155	7.0e-07	47.3	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
644850644	852	52.66	1	852	2	797	0.0e+00	1039	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
644850647	186	25.91	1	186	4	189	1.0e-08	53	COG3166	Tfp pilus assembly protein PilN	206
644850651	189	54.71	20	189	2	169	7.0e-55	206	COG0703	Shikimate kinase	172
644850652	361	59	1	361	1	359	0.0e+00	507	COG0337	3-dehydroquinate synthetase	360
644850653	350	39.1	39	348	9	291	3.0e-37	149	COG3266	Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain	292
644850654	275	51.1	3	270	1	271	1.0e-77	283	COG0338	Site-specific DNA-adenine methylase	274
644850655	225	60.36	1	222	1	220	2.0e-88	318	COG0036	Pentose-5-phosphate-3-epimerase	220
644850656	232	45.87	4	221	1	216	4.0e-48	184	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
644850657	334	52.83	1	312	3	314	3.0e-115	408	COG0180	Tryptophanyl-tRNA synthetase	314
644850658	384	31.52	1	382	1	369	1.0e-59	224	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644850659	191	49.69	30	190	1	158	2.0e-51	195	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
644850660	421	21.49	5	359	10	341	7.0e-06	45.4	COG3866	Pectate lyase	345
644850666	380	22.43	60	365	67	377	1.0e-06	47.9	COG2807	Cyanate permease	395
644850667	208	46.8	2	204	1	201	1.0e-53	202	COG3179	Predicted chitinase	206
644850670	401	35.09	280	393	12	124	3.0e-18	86.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644850671	106	34.78	13	103	19	110	7.0e-11	59.1	COG4679	Phage-related protein	116
644850673	191	64.4	1	191	3	190	2.0e-84	305	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
644850674	413	55.77	7	412	1	402	0.0e+00	565	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
644850675	257	28.35	1	257	1	252	7.0e-52	197	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
644850676	290	53.57	9	287	6	285	4.0e-109	387	COG3623	L-ribulose-5-phosphate 3-epimerase UlaE	287
644850677	355	23.23	32	328	1	254	3.0e-37	149	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
644850678	581	47.67	1	459	1	471	0.0e+00	485	COG3037	Ascorbate-specific PTS system EIIC-type component UlaA	481
644850679	158	28.66	5	156	3	152	6.0e-22	97	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
644850680	230	37.23	1	230	4	219	9.0e-55	206	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
644850681	214	51.39	1	214	1	216	4.0e-69	254	COG0269	3-keto-L-gulonate-6-phosphate decarboxylase	217
644850682	210	36.95	9	210	13	214	2.0e-40	158	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
644850683	135	54.01	1	133	2	137	2.0e-32	131	COG1765	Uncharacterized OsmC-related protein	137
644850684	289	85.76	1	288	1	288	0.0e+00	519	COG3954	Phosphoribulokinase	289
644850685	76	81.43	1	70	1	70	3.0e-25	106	COG3089	Uncharacterized conserved protein YheU, UPF0270 family	72
644850686	331	57.36	11	329	19	343	1.0e-108	386	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
644850687	201	33.68	4	191	3	195	5.0e-20	91.1	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644850688	639	46.88	1	519	3	527	0.0e+00	548	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644850689	183	34.92	6	179	2	189	2.0e-40	158	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
644850690	604	46.25	1	392	2	396	3.0e-74	273	COG0475	Kef-type K+ transport system, membrane component KefB	397
644850691	64	46.03	2	64	4	66	3.0e-12	63.5	COG3529	Predicted nucleic-acid-binding protein, contains Zn-ribbon domain	66
644850692	192	52.87	1	173	1	174	4.0e-49	187	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
644850693	455	26.77	1	443	6	450	1.0e-26	114	COG0531	Amino acid transporter	466
644850694	338	28.7	2	334	1	322	3.0e-44	172	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
644850695	347	34.43	227	347	1	121	6.0e-19	88.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644850696	72	59.72	1	72	1	72	9.0e-13	65	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
644850697	283	52.86	50	258	2	205	3.0e-54	205	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
644850698	385	25.68	36	361	2	327	6.0e-27	115	COG0642	Signal transduction histidine kinase	336
644850699	232	40	1	220	1	229	4.0e-54	204	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644850700	547	41.62	1	544	1	545	0.0e+00	510	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
644850701	240	62.73	19	235	1	220	5.0e-78	284	COG2964	Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains	220
644850702	129	50.78	2	129	1	126	3.0e-38	150	COG1553	Sulfur relay (sulfurtransferase) complex TusBCD TusD component, DsrE family	126
644850703	119	63.03	1	119	1	118	5.0e-41	159	COG2923	Sulfur relay (sulfurtransferase) complex TusC component, DsrF/TusC family	118
644850704	95	59.38	1	95	1	96	1.0e-23	101	COG2168	Sulfur transfer complex TusBCD TusB component, DsrH family	96
644850705	124	76.42	1	123	7	129	6.0e-50	189	COG0048	Ribosomal protein S12	129
644850706	156	61.49	2	149	1	148	2.0e-53	201	COG0049	Ribosomal protein S7	148
644850707	704	67.28	1	704	1	693	0.0e+00	1018	COG0480	Translation elongation factor EF-G, a GTPase	697
644850708	394	86.8	1	394	1	394	0.0e+00	728	COG0050	Translation elongation factor EF-Tu, a GTPase	394
644850709	64	48.44	1	64	1	63	7.0e-12	62.2	COG2906	Bacterioferritin-associated ferredoxin	63
644850710	157	70.7	1	157	1	157	2.0e-58	218	COG2193	Bacterioferritin (cytochrome b1)	157
644850711	103	74.51	1	102	1	102	1.0e-38	151	COG0051	Ribosomal protein S10	104
644850712	209	63.68	1	209	1	212	4.0e-78	284	COG0087	Ribosomal protein L3	218
644850713	201	47.62	1	201	2	211	2.0e-55	208	COG0088	Ribosomal protein L4	214
644850714	100	60.64	7	99	1	94	3.0e-23	99.9	COG0089	Ribosomal protein L23	94
644850715	273	68.36	1	273	1	275	6.0e-113	400	COG0090	Ribosomal protein L2	275
644850716	92	71.74	1	92	1	92	1.0e-37	148	COG0185	Ribosomal protein S19	93
644850717	110	67.27	1	110	9	118	2.0e-35	140	COG0091	Ribosomal protein L22	120
644850718	233	63.68	12	233	1	223	8.0e-80	289	COG0092	Ribosomal protein S3	233
644850719	136	63.24	1	133	2	137	3.0e-47	180	COG0197	Ribosomal protein L16/L10AE	146
644850720	63	56.45	2	63	4	65	1.0e-08	51.4	COG0255	Ribosomal protein L29	69
644850721	84	54.88	1	82	4	85	4.0e-25	106	COG0186	Ribosomal protein S17	87
644850722	123	75.61	1	123	1	122	2.0e-49	187	COG0093	Ribosomal protein L14	122
644850723	104	55.24	1	103	1	103	2.0e-18	83.8	COG0198	Ribosomal protein L24	104
644850724	179	67.6	1	179	1	179	2.0e-80	291	COG0094	Ribosomal protein L5	180
644850725	101	63.93	41	101	1	61	9.0e-18	81.8	COG0199	Ribosomal protein S14	61
644850726	130	58.78	1	129	1	131	1.0e-46	178	COG0096	Ribosomal protein S8	132
644850727	177	55.93	1	176	1	176	9.0e-60	222	COG0097	Ribosomal protein L6P/L9E	178
644850728	117	50.83	1	117	6	125	2.0e-29	120	COG0256	Ribosomal protein L18	125
644850729	166	62.8	4	166	17	180	6.0e-59	220	COG0098	Ribosomal protein S5	181
644850730	59	60	5	59	1	55	9.0e-15	71.7	COG1841	Ribosomal protein L30/L7E	55
644850731	144	54.67	1	144	1	150	2.0e-33	135	COG0200	Ribosomal protein L15	152
644850732	443	53.99	1	434	1	432	5.0e-130	457	COG0201	Preprotein translocase subunit SecY	436
644850733	38	76.32	1	38	1	38	7.0e-06	42.1	COG0257	Ribosomal protein L36	38
644850734	118	65.55	1	118	1	119	6.0e-41	159	COG0099	Ribosomal protein S13	121
644850736	206	62.98	1	206	1	205	6.0e-60	223	COG0522	Ribosomal protein S4 or related protein	205
644850737	329	59.43	8	323	1	313	1.0e-98	353	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
644850738	130	73.28	1	116	1	116	8.0e-47	179	COG0203	Ribosomal protein L17	116
644850740	74	67.19	4	67	5	66	1.0e-15	74.7	COG3036	Stalled ribosome alternative rescue factor ArfA	66
644850741	141	60.74	1	133	1	130	1.0e-42	165	COG1970	Large-conductance mechanosensitive channel	130
644850742	458	35.34	1	230	1	225	7.0e-48	185	COG0569	Trk K+ transport system, NAD-binding component	225
644850743	431	42.54	93	430	1	355	9.0e-98	350	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
644850744	313	55.3	2	303	1	302	5.0e-122	430	COG0223	Methionyl-tRNA formyltransferase	307
644850745	169	54.76	1	164	1	168	1.0e-56	211	COG0242	Peptide deformylase	168
644850746	377	40.11	1	365	1	350	1.0e-94	340	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
644850747	157	73.89	1	157	1	157	1.0e-56	212	COG2922	Uncharacterized conserved protein Smg, DUF494 family	157
644850748	185	36.43	54	180	11	139	4.0e-22	97.9	COG0551	ssDNA-binding Zn-finger and Zn-ribbon domains of topoisomerase 1	140
644850749	190	40.1	3	190	9	197	2.0e-49	188	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
644850750	275	40.29	4	274	6	282	7.0e-78	284	COG0169	Shikimate 5-dehydrogenase	283
644850752	178	49.14	4	178	3	170	3.0e-56	210	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
644850758	309	66.78	1	306	1	307	0.0e+00	497	COG1897	Homoserine trans-succinylase	307
644850759	532	49.62	20	531	24	541	0.0e+00	643	COG2225	Malate synthase	545
644850760	435	74.94	2	435	1	433	0.0e+00	666	COG2224	Isocitrate lyase	433
644850761	585	76.52	1	575	1	575	0.0e+00	933	COG4579	Isocitrate dehydrogenase kinase/phosphatase	578
644850762	277	41.94	29	275	1	246	3.0e-61	228	COG1414	DNA-binding transcriptional regulator, IclR family	246
644850763	1228	63.97	329	1193	1	842	0.0e+00	1220	COG1410	Methionine synthase I, cobalamin-binding domain	842
644850764	484	35.16	11	483	5	461	2.0e-58	220	COG0471	Di- and tricarboxylate transporter	461
644850765	548	45.95	1	531	4	530	0.0e+00	473	COG1283	Na+/phosphate symporter	533
644850766	454	38.05	8	454	2	446	1.0e-119	423	COG0527	Aspartokinase	447
644850767	549	54.27	49	538	4	446	0.0e+00	571	COG0166	Glucose-6-phosphate isomerase	446
644850769	345	52.87	2	345	1	347	1.0e-126	446	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
644850770	188	47.33	1	131	1	131	3.0e-41	161	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
644850771	117	60.71	1	112	5	115	9.0e-35	138	COG3169	Uncharacterized conserved protein, DUF486 family	116
644850772	179	46.47	1	170	1	168	8.0e-49	186	COG3040	Bacterial lipocalin	174
644850773	118	70.34	1	118	1	118	2.0e-39	154	COG3080	Fumarate reductase subunit D	118
644850774	131	60.16	3	130	2	129	2.0e-42	164	COG3029	Fumarate reductase subunit C	129
644850775	244	48.73	5	239	1	234	8.0e-87	313	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
644850776	598	53.89	1	572	2	562	0.0e+00	646	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
644850777	325	71.08	1	325	1	322	0.0e+00	496	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
644850778	1107	36.2	195	1087	1	810	0.0e+00	645	COG3264	Small-conductance mechanosensitive channel	835
644850779	304	32.25	9	280	2	237	2.0e-55	209	COG0688	Phosphatidylserine decarboxylase	239
644850780	349	38.41	30	344	3	301	8.0e-100	357	COG1162	Putative ribosome biogenesis GTPase RsgA	301
644850781	180	78.33	1	180	2	181	3.0e-88	317	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
644850784	439	19.79	158	425	17	302	3.0e-08	53.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644850788	502	20.24	55	464	44	443	4.0e-15	76.7	COG1538	Outer membrane protein TolC	457
644850789	530	33.8	183	518	48	408	1.0e-38	154	COG0840	Methyl-accepting chemotaxis protein	408
644850790	556	34.15	134	515	2	408	3.0e-47	183	COG0840	Methyl-accepting chemotaxis protein	408
644850791	298	28.37	7	294	3	288	2.0e-39	156	COG0583	DNA-binding transcriptional regulator, LysR family	297
644850792	443	34.18	17	439	10	391	7.0e-78	284	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
644850793	483	23.85	13	457	7	392	5.0e-53	202	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
644850794	329	28.53	3	314	2	303	5.0e-17	81.9	COG3547	Transposase	303
644850795	505	49.5	11	505	14	514	0.0e+00	538	COG2978	p-Aminobenzoyl-glutamate transporter AbgT	516
644850796	156	47.92	28	123	1	96	3.0e-13	68	COG1846	DNA-binding transcriptional regulator, MarR family	126
644850797	141	53.15	1	141	1	143	9.0e-42	162	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
644850798	336	37.06	29	336	6	312	5.0e-54	205	COG0657	Acetyl esterase/lipase	312
644850799	272	57.83	24	272	3	240	2.0e-102	365	COG1126	ABC-type polar amino acid transport system, ATPase component	240
644850800	311	38.03	55	288	6	221	4.0e-41	162	COG0765	ABC-type amino acid transport system, permease component	222
644850802	315	28.1	60	296	32	265	1.0e-25	110	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644850803	458	27.06	42	426	10	336	7.0e-45	175	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
644850804	329	27.16	16	324	8	329	7.0e-33	134	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
644850807	84	76.06	1	71	1	71	9.0e-26	108	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
644850808	432	26.73	1	411	3	406	2.0e-34	140	COG1457	Purine-cytosine permease or related protein	442
644850810	95	74.63	4	70	5	71	1.0e-23	101	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
644850811	172	44.77	1	172	1	160	2.0e-50	191	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
644850812	617	43.69	1	544	6	550	0.0e+00	555	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
644850813	135	35.04	1	131	3	139	5.0e-26	110	COG5435	Uncharacterized protein	147
644850814	1475	21.54	576	1349	11	692	4.0e-36	147	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
644850817	533	40.63	194	532	112	457	8.0e-94	338	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644850859	670	30.29	1	619	1	570	0.0e+00	495	COG0550	DNA topoisomerase IA	570
644850872	70	41.79	3	69	2	68	9.0e-15	71.9	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
644850873	308	32.3	1	308	3	324	1.0e-56	213	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
644850875	379	56.18	10	347	2	337	3.0e-115	408	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
644850876	513	47.67	234	505	8	284	1.0e-68	254	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
644850877	160	55.7	4	151	1	149	3.0e-48	184	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
644850878	560	39.32	169	402	37	231	2.0e-52	200	COG0860	N-acetylmuramoyl-L-alanine amidase	231
644850879	649	40.46	1	649	1	637	0.0e+00	592	COG0323	DNA mismatch repair ATPase MutL	638
644850880	313	52.29	9	311	2	305	8.0e-105	373	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
644850881	99	71.43	1	76	1	77	1.0e-25	108	COG1923	sRNA-binding regulator protein Hfq	77
644850882	433	53.12	6	421	1	409	0.0e+00	466	COG2262	50S ribosomal subunit-associated GTPase HflX	411
644850883	420	34.83	74	354	3	289	4.0e-53	202	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
644850884	331	27.63	1	326	2	288	1.0e-42	167	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
644850885	66	64.52	1	62	1	62	6.0e-14	69.1	COG3242	Uncharacterized conserved protein YjeT, DUF2065 family	62
644850886	432	65.58	2	430	1	429	0.0e+00	668	COG0104	Adenylosuccinate synthase	430
644850887	460	41.96	2	449	9	457	0.0e+00	522	COG0773	UDP-N-acetylmuramate-alanine ligase	459
644850888	334	66.87	1	332	1	326	0.0e+00	498	COG0158	Fructose-1,6-bisphosphatase	326
644850889	143	47.48	3	140	1	139	4.0e-44	170	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
644850890	187	53.72	1	187	11	194	6.0e-66	243	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
644850891	317	43.56	2	315	1	316	7.0e-79	287	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
644850892	244	46.37	1	242	1	246	2.0e-71	262	COG1385	16S rRNA U1498 N3-methylase RsmE	246
644850893	233	73.31	1	232	1	234	3.0e-96	344	COG2356	Endonuclease I	237
644850894	170	49.34	12	163	1	151	3.0e-46	177	COG3091	Predicted Zn-dependent metalloprotease, SprT family	156
644850895	384	71.32	1	383	2	388	0.0e+00	699	COG0192	S-adenosylmethionine synthetase	388
644850897	658	69.28	10	658	5	652	0.0e+00	1029	COG1166	Arginine decarboxylase (spermidine biosynthesis)	652
644850898	397	18.25	9	395	21	422	6.0e-13	69.1	COG0738	Fucose permease	422
644850899	664	68.07	1	664	3	663	0.0e+00	1070	COG0021	Transketolase	663
644850901	338	49.85	2	335	1	331	7.0e-117	413	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
644850902	387	57.39	1	386	2	395	0.0e+00	499	COG0126	3-phosphoglycerate kinase	395
644850903	358	35.09	17	356	5	284	1.0e-88	320	COG0191	Fructose/tagatose bisphosphate aldolase	286
644850904	292	35.29	13	292	24	312	4.0e-41	161	COG0668	Small-conductance mechanosensitive channel	316
644850905	272	40.73	20	267	1	245	1.0e-60	226	COG1414	DNA-binding transcriptional regulator, IclR family	246
644850906	251	43.21	11	249	3	243	6.0e-60	224	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
644850907	297	26.67	4	296	1	297	8.0e-23	101	COG0583	DNA-binding transcriptional regulator, LysR family	297
644850908	220	53.54	1	218	1	226	4.0e-76	277	COG0120	Ribose 5-phosphate isomerase	227
644850909	410	44.41	8	335	1	323	6.0e-91	328	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
644850910	333	31.14	4	332	2	325	2.0e-61	229	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
644850911	298	34.26	5	285	3	286	3.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
644850912	568	39.79	174	525	32	408	4.0e-46	179	COG0840	Methyl-accepting chemotaxis protein	408
644850913	554	47.42	3	536	1	529	0.0e+00	567	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644850914	643	28.86	344	634	1	295	1.0e-32	135	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
644850915	110	63.16	12	106	7	101	3.0e-28	116	COG2973	Trp operon repressor	103
644850916	179	47.73	1	171	1	173	4.0e-49	187	COG1986	Non-canonical (house-cleaning) NTP pyrophosphatase, all-alpha NTP-PPase family	175
644850917	216	35.9	1	193	2	195	6.0e-41	160	COG0406	Broad specificity phosphatase PhoE	208
644850918	288	36.63	6	106	21	121	1.0e-21	97.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644850919	158	61.78	1	157	3	156	1.0e-59	222	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
644850920	238	38.89	4	235	1	228	7.0e-52	197	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644850921	233	39.83	1	232	3	242	5.0e-55	207	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
644850922	818	45.24	1	460	3	445	0.0e+00	465	COG0527	Aspartokinase	447
644850923	309	43.69	1	309	3	298	5.0e-102	364	COG0083	Homoserine kinase	299
644850924	429	32.04	1	426	1	410	1.0e-96	346	COG0498	Threonine synthase	411
644850925	260	64.06	1	256	1	252	5.0e-92	330	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
644850926	317	38.73	5	315	1	239	2.0e-68	252	COG0176	Transaldolase	239
644850927	381	44.65	203	359	20	177	1.0e-36	147	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644850928	195	43.18	4	178	8	169	1.0e-46	179	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
644850929	445	21.28	72	414	63	381	2.0e-09	57.1	COG2814	Predicted arabinose efflux permease, MFS family	394
644850930	190	66.31	6	186	19	205	5.0e-54	203	COG1584	Succinate-acetate transporter protein	207
644850931	636	60.89	1	605	4	579	0.0e+00	672	COG0443	Molecular chaperone DnaK (HSP70)	579
644850932	377	64.46	1	374	1	371	0.0e+00	525	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
644850933	401	58.93	8	399	1	389	1.0e-116	413	COG3004	Na+/H+ antiporter NhaA	390
644850934	296	21.95	4	285	1	283	2.0e-24	106	COG0583	DNA-binding transcriptional regulator, LysR family	297
644850935	87	64.37	1	87	1	87	1.0e-14	71.5	COG0268	Ribosomal protein S20	88
644850936	313	52.12	1	307	1	303	2.0e-103	368	COG0196	FAD synthase	304
644850937	941	51.37	2	935	1	933	0.0e+00	1277	COG0060	Isoleucyl-tRNA synthetase	933
644850938	170	45.51	3	166	2	164	1.0e-38	152	COG0597	Lipoprotein signal peptidase	167
644850939	152	42.36	5	148	3	145	7.0e-38	149	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
644850940	316	66.78	1	295	2	294	2.0e-128	451	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
644850941	305	46.77	3	305	2	311	8.0e-94	337	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
644850942	273	58.49	6	270	3	266	1.0e-98	353	COG0289	Dihydrodipicolinate reductase	266
644850943	381	62.7	3	380	2	368	0.0e+00	594	COG0505	Carbamoylphosphate synthase small subunit	368
644850944	1074	70.96	13	408	1	393	0.0e+00	584	COG0458	Carbamoylphosphate synthase large subunit	400
644850945	204	35.75	1	204	2	206	1.0e-27	116	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644850946	260	39.75	4	244	8	250	7.0e-60	223	COG2966	Uncharacterized membrane protein YjjP, DUF1212 family	250
644850947	156	48.7	5	156	2	155	4.0e-31	127	COG3610	Uncharacterized membrane protein YjjB, DUF3815 family	156
644850948	160	45.83	3	160	2	167	2.0e-39	155	COG0262	Dihydrofolate reductase	167
644850949	634	49.04	23	634	23	616	0.0e+00	602	COG3211	Secreted phosphatase, PhoX family	616
644850950	281	24.59	146	263	34	155	9.0e-11	61.2	COG0639	Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family	155
644850951	125	64	1	125	2	126	8.0e-50	188	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
644850952	272	50.58	11	268	4	258	1.0e-89	323	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
644850953	333	56.06	5	331	1	329	5.0e-119	421	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
644850954	430	22.03	4	340	1	320	3.0e-18	86.7	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
644850955	807	39.33	13	807	1	784	0.0e+00	647	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
644850957	217	41.52	1	217	71	289	1.0e-58	219	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644850958	967	27.55	59	944	8	834	5.0e-64	240	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
644850959	790	34.73	7	790	5	788	0.0e+00	615	COG0417	DNA polymerase elongation subunit (family B)	792
644850963	182	36.48	24	178	1	155	4.0e-33	134	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
644850968	255	36.41	8	200	8	202	5.0e-32	131	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
644850970	554	48.64	4	552	3	550	0.0e+00	615	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
644850971	230	62.17	1	229	1	230	3.0e-84	304	COG3840	ABC-type thiamine transport system, ATPase component	231
644850972	537	37.73	1	537	1	539	7.0e-84	305	COG1178	ABC-type Fe3+ transport system, permease component	540
644850973	327	63.96	1	327	4	336	5.0e-129	454	COG4143	ABC-type thiamine transport system, periplasmic component	336
644850974	555	52.46	1	550	1	564	0.0e+00	581	COG4533	DNA-binding transcriptional regulator SgrR  of sgrS sRNA, contains a MarR-type HTH domain and a periplasmic-type solute-binding domain	564
644850976	466	62.39	1	466	5	471	0.0e+00	664	COG3033	Tryptophanase	471
644850978	300	33.33	6	298	14	262	1.0e-44	173	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
644850979	329	28.53	3	314	2	303	5.0e-17	81.9	COG3547	Transposase	303
644850980	200	58.21	1	200	1	191	6.0e-82	296	COG0066	3-isopropylmalate dehydratase small subunit	191
644850981	466	60.13	1	465	1	422	0.0e+00	644	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
644850982	363	57.26	2	362	1	348	0.0e+00	464	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
644850983	524	50.12	3	414	1	409	2.0e-126	446	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
644850984	601	42.74	8	601	15	609	0.0e+00	636	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
644850985	573	51.68	3	565	1	549	0.0e+00	683	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
644850986	163	56.79	1	162	3	163	2.0e-48	185	COG0440	Acetolactate synthase, small subunit	163
644850987	334	30.72	1	329	1	327	3.0e-61	229	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644850990	152	51.97	1	152	1	146	2.0e-46	178	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
644850991	313	56.47	1	312	1	313	6.0e-116	410	COG0275	16S rRNA C1402 N4-methylase RsmH	314
644850992	107	65.71	1	105	1	105	3.0e-30	123	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
644850993	587	39.6	8	566	2	598	0.0e+00	469	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
644850994	494	49.05	21	493	9	475	0.0e+00	489	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
644850995	453	48.13	2	450	1	451	0.0e+00	465	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
644850996	360	46.97	20	360	1	316	4.0e-62	232	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
644850997	437	49.01	1	437	3	447	0.0e+00	481	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
644850998	400	46.05	29	389	13	374	4.0e-88	318	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
644850999	363	45.38	6	353	1	355	7.0e-104	370	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
644851000	486	55.56	13	477	1	455	0.0e+00	606	COG0773	UDP-N-acetylmuramate-alanine ligase	459
644851002	284	33.21	1	268	3	269	9.0e-52	197	COG1589	Cell division septal protein FtsQ	269
644851003	418	51.43	8	418	6	418	0.0e+00	486	COG0849	Cell division ATPase FtsA	418
644851004	383	56.97	2	337	3	338	3.0e-102	365	COG0206	Cell division GTPase FtsZ	338
644851005	305	70.53	1	302	1	300	0.0e+00	491	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
644851006	174	31.29	2	164	1	162	7.0e-32	130	COG4701	Uncharacterized protein	162
644851008	897	62.27	2	889	1	822	0.0e+00	1142	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
644851009	132	33.61	7	121	11	129	1.0e-12	65.8	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
644851010	73	59.38	9	72	1	64	7.0e-18	82.4	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
644851011	249	61.07	7	249	1	244	3.0e-83	301	COG4582	Cell division protein ZapD, interacts with FtsZ	244
644851012	208	44.28	1	201	1	201	1.0e-58	219	COG0237	Dephospho-CoA kinase	201
644851013	346	25.12	139	345	2	168	2.0e-26	113	COG0516	IMP dehydrogenase/GMP reductase	170
644851014	401	37.44	4	398	1	396	2.0e-84	306	COG1459	Type II secretory pathway, component PulF	397
644851015	473	44.38	10	469	21	499	0.0e+00	464	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
644851016	147	34.15	3	123	4	125	1.0e-20	92.7	COG4969	Tfp pilus assembly protein, major pilin PilA	125
644851017	296	53.96	22	295	5	277	4.0e-94	337	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
644851018	287	60.41	1	287	5	284	2.0e-80	292	COG3248	Nucleoside-specific outer membrane channel protein Tsx	284
644851020	284	55.86	1	284	1	282	1.0e-69	256	COG3725	Membrane protein required for beta-lactamase induction	282
644851021	448	55.01	1	447	3	451	0.0e+00	539	COG1113	L-asparagine transporter and related permeases	462
644851022	254	41.22	1	242	1	241	3.0e-44	171	COG2186	DNA-binding transcriptional regulator, FadR family	241
644851023	887	75.59	1	887	1	887	0.0e+00	1507	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
644851024	626	44.16	201	626	1	403	3.0e-97	349	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
644851025	474	52.52	3	456	1	454	0.0e+00	498	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
644851026	392	24.89	111	339	9	179	2.0e-12	67.3	COG0412	Dienelactone hydrolase	236
644851027	443	26.54	1	387	3	390	3.0e-43	169	COG2079	2-methylcitrate dehydratase PrpD	453
644851028	865	84.44	1	861	1	852	0.0e+00	1545	COG1049	Aconitase B	852
644851029	120	69.17	1	119	1	120	3.0e-40	156	COG3112	Uncharacterized protein YacL, UPF0231 family	121
644851030	537	28.72	162	518	26	408	7.0e-33	135	COG0840	Methyl-accepting chemotaxis protein	408
644851031	227	30.12	1	224	2	249	4.0e-29	121	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644851032	157	32.69	1	153	1	154	8.0e-25	106	COG2731	Beta-galactosidase, beta subunit	154
644851033	391	37.72	1	390	1	377	9.0e-63	234	COG4692	Predicted neuraminidase (sialidase)	381
644851034	472	18.42	9	440	5	459	3.0e-23	103	COG0591	Na+/proline symporter	493
644851035	294	38.01	1	290	1	288	3.0e-69	255	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
644851036	378	35.79	1	378	4	377	4.0e-84	305	COG1454	Alcohol dehydrogenase, class IV	377
644851037	428	32.48	8	423	1	413	2.0e-58	219	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
644851038	326	50.76	1	326	2	326	3.0e-104	371	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
644851039	276	40.96	25	272	6	253	8.0e-60	223	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
644851041	505	29.4	39	497	8	486	2.0e-81	296	COG2368	Aromatic ring hydroxylase	493
644851042	292	38.62	5	292	14	302	4.0e-70	258	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
644851043	284	43.37	4	281	1	274	5.0e-35	141	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
644851044	239	38.56	7	236	5	240	2.0e-59	222	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
644851046	303	35.09	17	296	6	290	1.0e-45	177	COG2971	BadF-type ATPase, related to human N-acetylglucosamine kinase	301
644851047	435	23.6	7	333	10	343	2.0e-29	123	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
644851049	369	43.3	53	363	33	347	1.0e-71	263	COG4225	Rhamnogalacturonyl hydrolase YesR	357
644851050	366	53.39	1	353	1	338	2.0e-129	455	COG3839	ABC-type sugar transport system, ATPase component	338
644851051	333	42.05	34	333	8	294	3.0e-53	202	COG1175	ABC-type sugar transport system, permease component	295
644851052	350	44.13	108	350	38	281	3.0e-56	212	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
644851053	343	33.24	2	341	1	330	2.0e-59	222	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644851055	345	19.7	24	155	5	126	4.0e-06	46.1	COG3415	Transposase	138
644851062	139	30	12	131	1	116	5.0e-16	76.9	COG3628	Phage baseplate assembly protein W	116
644851063	99	47.06	1	99	1	98	1.0e-10	58	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
644851064	596	21.33	16	361	10	350	9.0e-36	145	COG3500	Phage protein D	350
644851074	209	25.73	1	204	1	198	5.0e-09	54.5	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
644851075	192	20.77	3	185	1	173	3.0e-20	92	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
644851079	182	45	5	182	2	167	2.0e-39	155	COG0629	Single-stranded DNA-binding protein	167
644851080	943	69.57	1	942	3	935	0.0e+00	1598	COG0178	Excinuclease UvrABC ATPase subunit	935
644851081	139	47.48	1	138	2	137	6.0e-41	159	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
644851082	536	40.46	357	524	9	180	1.0e-40	161	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644851083	561	39.37	194	516	61	408	3.0e-48	187	COG0840	Methyl-accepting chemotaxis protein	408
644851084	333	17.87	15	326	1	297	1.0e-46	180	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
644851090	397	57.58	1	396	1	395	0.0e+00	582	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
644851092	158	37.75	1	151	3	152	7.0e-26	110	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644851093	457	54.26	8	451	10	455	0.0e+00	532	COG1113	L-asparagine transporter and related permeases	462
644851094	255	26.59	1	255	1	267	1.0e-25	110	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644851096	358	51.24	1	358	2	360	2.0e-122	432	COG0787	Alanine racemase	360
644851097	467	50.11	21	461	1	435	0.0e+00	561	COG0305	Replicative DNA helicase	435
644851098	331	43.16	2	327	1	326	1.0e-78	286	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
644851099	459	24.51	7	456	4	410	6.0e-42	165	COG2124	Cytochrome P450	411
644851101	344	39.09	20	341	5	317	1.0e-84	306	COG0042	tRNA-dihydrouridine synthase	323
644851103	294	34.02	6	293	2	288	2.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
644851104	378	25.43	41	378	4	299	2.0e-28	120	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
644851105	169	53.66	47	168	44	166	1.0e-34	139	COG4925	Uncharacterized protein	166
644851106	400	36.48	21	397	12	392	9.0e-53	201	COG2814	Predicted arabinose efflux permease, MFS family	394
644851107	319	33.77	6	302	2	294	9.0e-32	131	COG0583	DNA-binding transcriptional regulator, LysR family	297
644851109	102	42.11	1	95	1	95	1.0e-19	88	COG5470	Uncharacterized conserved protein, DUF1330 family	96
644851110	178	27.37	1	176	1	189	5.0e-27	114	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
644851111	235	33.9	1	235	1	236	1.0e-47	183	COG2188	DNA-binding transcriptional regulator, GntR family	236
644851112	350	23.43	52	347	1	299	3.0e-35	142	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
644851114	280	46.79	1	275	1	278	5.0e-77	281	COG4132	ABC-type uncharacterized transport system, permease component	282
644851116	261	33.06	12	258	16	260	9.0e-39	153	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
644851117	330	46.57	1	330	3	351	9.0e-105	373	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644851118	446	21.41	117	436	43	348	4.0e-37	149	COG3177	Fic family protein	348
644851119	309	28.33	5	300	2	297	5.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
644851120	420	38.35	1	397	2	394	2.0e-95	343	COG0019	Diaminopimelate decarboxylase	394
644851121	336	39.22	2	333	1	333	4.0e-84	304	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644851122	108	38.24	1	102	1	102	1.0e-20	91.8	COG1447	Phosphotransferase system cellobiose-specific component IIA	105
644851123	448	39.86	14	442	15	432	2.0e-94	339	COG1455	Phosphotransferase system cellobiose-specific component IIC	432
644851124	478	39.43	6	463	2	449	9.0e-115	407	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
644851125	105	49.52	1	105	1	101	2.0e-27	114	COG1440	Phosphotransferase system cellobiose-specific component IIB	102
644851126	255	35.04	10	236	9	239	5.0e-42	164	COG2186	DNA-binding transcriptional regulator, FadR family	241
644851128	155	42.41	1	154	1	154	1.0e-38	151	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
644851131	238	26.06	7	193	13	194	3.0e-26	111	COG2184	Fido, protein-threonine AMPylation domain	201
644851132	337	43.54	2	333	1	333	3.0e-88	318	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644851134	638	31.62	101	448	7	376	7.0e-61	228	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
644851135	496	44.76	12	496	2	458	0.0e+00	558	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
644851136	465	46.37	1	463	1	455	0.0e+00	543	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
644851137	732	31.05	196	715	1	527	3.0e-81	296	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644851139	151	49.34	1	151	1	152	4.0e-48	183	COG2153	Predicted N-acyltransferase, GNAT family	155
644851140	463	40.66	273	454	3	180	2.0e-44	173	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644851141	379	44.27	6	378	34	412	1.0e-119	423	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
644851142	197	57.14	1	195	1	191	2.0e-66	244	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
644851143	100	51.02	6	99	4	101	6.0e-25	105	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
644851144	184	33.33	89	183	1	96	7.0e-07	47.1	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
644851145	273	44.4	5	271	3	265	6.0e-69	254	COG0345	Pyrroline-5-carboxylate reductase	266
644851146	241	56.28	10	239	2	228	4.0e-86	311	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
644851147	340	57.35	1	339	3	341	2.0e-128	452	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
644851149	417	30.17	3	405	11	400	4.0e-56	212	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
644851151	528	33.33	166	518	31	408	1.0e-46	180	COG0840	Methyl-accepting chemotaxis protein	408
644851152	141	47.76	1	131	1	134	2.0e-34	138	COG1959	DNA-binding transcriptional regulator, IscR family	150
644851153	822	50.7	17	724	3	706	0.0e+00	781	COG0557	Exoribonuclease R	706
644851154	244	48.36	1	243	20	258	3.0e-70	258	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
644851155	505	38.52	116	495	4	408	5.0e-47	182	COG0840	Methyl-accepting chemotaxis protein	408
644851158	646	33.82	327	644	66	408	7.0e-49	189	COG0840	Methyl-accepting chemotaxis protein	408
644851159	249	25.46	8	249	30	298	2.0e-18	86.7	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
644851160	130	52.68	2	112	1	112	2.0e-34	137	COG0360	Ribosomal protein S6	112
644851161	106	67.96	1	103	1	103	7.0e-38	148	COG2965	Primosomal replication protein N	103
644851162	75	72.06	1	68	8	75	2.0e-20	90.7	COG0238	Ribosomal protein S18	75
644851163	149	57.05	1	149	1	147	1.0e-42	165	COG0359	Ribosomal protein L9	148
644851164	124	43.86	5	116	4	116	3.0e-25	106	COG3189	Uncharacterized conserved protein YeaO, DUF488 family	117
644851165	234	33.2	1	234	1	242	3.0e-32	132	COG3061	Cell envelope opacity-associated protein A (function unknown)	242
644851166	206	51.46	1	206	1	205	1.0e-61	229	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
644851168	221	64.71	1	221	1	221	4.0e-89	321	COG2846	Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains	221
644851169	648	35.44	3	565	1	517	4.0e-118	419	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
644851170	246	58.2	1	244	8	262	4.0e-83	301	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
644851172	438	36.03	1	429	3	426	3.0e-103	369	COG1253	Hemolysin or related protein, contains CBS domains	429
644851173	213	55.81	41	212	3	171	6.0e-71	260	COG0225	Peptide methionine sulfoxide reductase MsrA	174
644851174	594	46.1	25	594	18	594	0.0e+00	569	COG0729	Outer membrane translocation and assembly module TamA	594
644851175	1246	42.42	2	1246	12	1278	0.0e+00	968	COG2911	Autotransporter translocation and assembly factor TamB	1278
644851176	120	49.15	3	115	4	119	3.0e-25	106	COG2105	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family	120
644851177	176	61.71	1	175	1	171	2.0e-59	221	COG0221	Inorganic pyrophosphatase	171
644851178	542	32.19	136	517	2	408	1.0e-45	177	COG0840	Methyl-accepting chemotaxis protein	408
644851179	213	50.5	1	193	1	200	9.0e-58	216	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
644851180	120	48.28	1	115	2	117	8.0e-34	135	COG1539	Dihydroneopterin aldolase	121
644851181	273	54.78	3	273	2	268	3.0e-71	262	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
644851182	415	39.04	1	391	23	405	4.0e-84	305	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
644851183	207	48.78	2	206	1	205	6.0e-59	220	COG3103	Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family	205
644851184	443	44.92	1	443	1	432	6.0e-98	351	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
644851185	966	55.48	33	965	28	954	0.0e+00	1060	COG1391	Glutamine synthetase adenylyltransferase	963
644851186	475	63	1	473	1	465	0.0e+00	717	COG2870	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase	467
644851187	682	58.87	12	682	5	667	0.0e+00	935	COG0272	NAD-dependent DNA ligase	667
644851188	73	78.57	1	70	1	69	5.0e-24	102	COG3530	Uncharacterized conserved protein, DUF3820 family	71
644851191	511	32.46	193	509	65	406	1.0e-44	174	COG0840	Methyl-accepting chemotaxis protein	408
644851192	524	48.18	115	524	1	381	1.0e-130	460	COG2721	Altronate dehydratase	381
644851193	450	22.79	18	435	27	433	4.0e-29	122	COG2271	Sugar phosphate permease	448
644851194	461	27.71	16	423	1	372	1.0e-59	224	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644851195	446	28.16	8	415	1	371	1.0e-59	224	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644851196	256	55.12	4	256	2	255	4.0e-97	347	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
644851197	294	51.4	1	285	1	286	8.0e-81	294	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
644851198	380	68.7	1	377	1	377	0.0e+00	522	COG1929	Glycerate kinase	378
644851199	922	37.31	254	520	78	333	2.0e-42	168	COG0642	Signal transduction histidine kinase	336
644851200	444	39.4	13	431	1	432	5.0e-112	398	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
644851201	745	53.4	9	742	1	701	0.0e+00	921	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
644851203	545	67.77	3	543	1	533	0.0e+00	917	COG0504	CTP synthase (UTP-ammonia lyase)	533
644851204	432	69.14	1	431	1	423	0.0e+00	628	COG0148	Enolase	423
644851205	524	27.86	1	474	4	462	3.0e-74	273	COG2211	Na+/melibiose symporter or related transporter	467
644851206	379	41.23	31	379	4	354	5.0e-95	341	COG4225	Rhamnogalacturonyl hydrolase YesR	357
644851207	324	24.02	89	292	29	212	5.0e-16	78.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644851208	223	35.24	1	223	2	212	8.0e-49	187	COG0602	Organic radical activating enzyme	212
644851209	122	45.74	1	120	1	127	5.0e-32	129	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
644851211	429	26.91	1	426	8	432	8.0e-44	171	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
644851213	607	57.82	17	607	1	587	0.0e+00	693	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
644851214	571	44.67	14	565	5	509	0.0e+00	547	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
644851215	244	38.78	7	244	1	243	1.0e-56	213	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
644851216	473	54.07	1	209	1	209	9.0e-60	224	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
644851216	473	64.49	213	455	2	244	2.0e-87	316	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
644851217	302	39.35	1	302	11	261	2.0e-62	232	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
644851218	475	67.13	22	453	1	431	0.0e+00	678	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
644851219	204	65.64	11	204	1	195	2.0e-85	308	COG0529	Adenylylsulfate kinase or related kinase	197
644851221	117	50.55	1	91	24	114	2.0e-23	100	COG2919	Cell division protein FtsB	117
644851222	235	50.44	10	230	4	228	1.0e-71	262	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
644851223	165	66.46	1	158	1	158	5.0e-66	243	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
644851224	352	37.95	7	342	11	396	2.0e-84	306	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
644851225	208	52.68	4	206	1	205	3.0e-68	251	COG2518	Protein-L-isoaspartate O-methyltransferase	209
644851226	404	31.4	111	402	4	262	3.0e-31	129	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
644851227	330	44.83	7	322	20	336	1.0e-75	276	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
644851228	572	47.9	1	568	1	500	0.0e+00	611	COG0442	Prolyl-tRNA synthetase	500
644851229	235	57.32	1	157	2	150	3.0e-52	198	COG1720	tRNA (Thr-GGU) A37 N-methylase	156
644851231	271	57.04	4	271	3	268	1.0e-91	329	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
644851232	217	59.45	1	217	6	222	3.0e-72	265	COG2011	ABC-type methionine transport system, permease component	222
644851233	343	63.85	1	342	1	339	0.0e+00	477	COG1135	ABC-type methionine transport system, ATPase component	339
644851234	188	52.38	1	188	1	181	3.0e-59	221	COG0241	Histidinol phosphatase or a related phosphatase	181
644851241	433	21.59	79	429	63	390	4.0e-12	66.4	COG2814	Predicted arabinose efflux permease, MFS family	394
644851242	109	60.22	15	107	9	100	7.0e-22	95.5	COG5544	Uncharacterized conserved protein YfiM, DUF2279 family	101
644851243	451	25.22	2	451	32	438	3.0e-47	183	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
644851244	888	44.9	3	626	1	598	0.0e+00	557	COG1042	Acyl-CoA synthetase (NDP forming)	598
644851245	238	66.06	2	222	1	220	2.0e-78	285	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
644851248	397	36.08	144	396	6	258	9.0e-61	227	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
644851250	391	43.02	10	352	1	344	6.0e-90	324	COG1566	Multidrug resistance efflux pump	352
644851251	170	31.36	44	161	11	126	2.0e-08	52.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
644851253	237	48.21	4	226	8	226	3.0e-38	151	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
644851254	399	25.58	1	386	1	383	1.0e-23	104	COG2814	Predicted arabinose efflux permease, MFS family	394
644851255	332	28.1	1	330	4	300	4.0e-56	212	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
644851256	400	62.5	103	382	9	288	4.0e-103	368	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
644851257	400	65.4	1	396	1	386	0.0e+00	516	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
644851258	494	39.66	13	475	20	486	2.0e-121	429	COG1953	Cytosine/uracil/thiamine/allantoin permease	497
644851259	247	34.95	14	217	15	219	2.0e-33	135	COG1802	DNA-binding transcriptional regulator, GntR family	230
644851260	245	49.12	6	232	3	230	4.0e-60	224	COG4126	Asp/Glu/hydantoin racemase	230
644851261	315	23.13	11	311	1	267	3.0e-27	116	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
644851262	448	17.56	35	425	1	369	1.0e-32	134	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
644851265	470	38.78	1	461	2	475	8.0e-99	354	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
644851267	529	36.08	4	529	11	539	1.0e-119	423	COG0405	Gamma-glutamyltranspeptidase	539
644851268	279	25.98	1	275	2	281	1.0e-43	170	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
644851269	240	27.53	2	237	24	270	2.0e-28	119	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644851270	221	45.97	7	216	8	218	2.0e-48	185	COG0765	ABC-type amino acid transport system, permease component	222
644851271	218	42.59	2	216	7	222	8.0e-51	193	COG0765	ABC-type amino acid transport system, permease component	222
644851272	243	57.26	2	242	1	240	2.0e-104	371	COG1126	ABC-type polar amino acid transport system, ATPase component	240
644851273	414	36.75	11	409	3	383	2.0e-105	376	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
644851274	416	22.2	9	412	1	403	8.0e-34	138	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644851275	255	34.33	2	255	1	267	7.0e-46	177	COG0388	Predicted amidohydrolase	274
644851276	385	34.95	21	385	20	388	4.0e-84	305	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
644851277	204	33.67	10	201	12	194	3.0e-34	138	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
644851278	236	48.08	1	208	3	209	2.0e-65	241	COG4229	Enolase-phosphatase E1 involved in merthionine salvage	229
644851279	180	46.11	1	179	1	174	1.0e-50	192	COG1791	Acireductone dioxygenase (methionine salvage), cupin superfamily	181
644851280	343	49.7	13	329	11	334	4.0e-102	364	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
644851281	400	44.44	33	380	37	387	2.0e-96	345	COG4857	5-Methylthioribose kinase, methionine salvage pathway	408
644851282	814	27.78	120	507	5	382	6.0e-46	179	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644851283	193	56.98	2	179	1	176	7.0e-66	243	COG0279	Phosphoheptose isomerase	176
644851284	255	50.79	1	254	1	247	5.0e-88	317	COG0121	Predicted glutamine amidotransferase	252
644851285	241	46.72	14	237	24	252	4.0e-64	237	COG3034	Murein L,D-transpeptidase YafK	298
644851286	352	41.41	2	347	1	352	9.0e-86	310	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
644851287	486	36.46	6	485	1	414	7.0e-106	378	COG2195	Di- or tripeptidase	414
644851289	152	18.67	1	144	14	179	5.0e-24	103	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
644851292	367	55.83	1	367	3	369	0.0e+00	472	COG0263	Glutamate 5-kinase	369
644851293	417	60.67	1	417	4	417	0.0e+00	595	COG0014	Gamma-glutamyl phosphate reductase	417
644851297	82	68.57	5	74	7	76	9.0e-22	95.1	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
644851299	291	18.6	19	246	1	252	5.0e-19	88.8	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
644851314	78	40.74	25	78	11	64	1.0e-06	44.9	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
644851317	535	35.89	5	531	3	486	3.0e-90	325	COG0286	Type I restriction-modification system, DNA methylase subunit	489
644851320	990	27.5	1	963	4	953	1.0e-122	434	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
644851321	288	43.73	1	288	1	295	5.0e-78	284	COG3596	Predicted GTPase	296
644851326	349	24.52	1	147	4	157	4.0e-16	79.2	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
644851328	306	31.21	2	295	1	292	4.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
644851329	148	26.49	1	145	1	143	7.0e-20	90	COG1959	DNA-binding transcriptional regulator, IscR family	150
644851330	215	37.14	1	208	2	196	8.0e-33	133	COG2085	Predicted dinucleotide-binding enzyme	211
644851331	299	28.24	16	270	12	266	9.0e-22	97.7	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
644851335	275	31.13	1	105	16	121	3.0e-16	79.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644851335	275	35.93	111	272	2	168	5.0e-32	131	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
644851338	372	24.37	6	371	4	383	3.0e-28	120	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
644851341	346	30.86	2	333	12	328	1.0e-48	187	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
644851343	207	41.92	1	198	2	198	2.0e-55	208	COG1182	FMN-dependent NADH-azoreductase	202
644851344	102	26.09	1	86	1	92	9.0e-06	41.8	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
644851345	563	61.36	3	559	1	553	0.0e+00	716	COG3275	Sensor histidine kinase, LytS/YehU family	557
644851346	241	46.91	1	239	1	243	2.0e-55	209	COG3279	DNA-binding response regulator, LytR/AlgR family	244
644851347	715	41.89	33	706	1	574	0.0e+00	582	COG1966	Carbon starvation protein CstA	575
644851348	67	67.16	1	67	1	65	1.0e-22	98.1	COG2879	Uncharacterized short protein YbdD, DUF466 family	65
644851349	322	41.67	6	319	1	320	3.0e-72	265	COG0523	GTPase, G3E family	323
644851350	347	30.51	221	338	2	116	2.0e-12	66.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644851351	459	25.81	4	417	14	432	1.0e-43	171	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644851352	562	26.43	1	518	1	458	7.0e-94	338	COG4690	Dipeptidase	464
644851353	474	22.27	236	442	53	223	1.0e-12	68	COG0688	Phosphatidylserine decarboxylase	239
644851354	330	40.38	1	311	4	309	7.0e-48	184	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
644851355	345	45.52	61	337	39	315	8.0e-48	184	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
644851356	500	49.8	9	500	8	499	0.0e+00	592	COG1129	ABC-type sugar transport system, ATPase component	500
644851357	318	34.08	8	314	18	320	6.0e-42	164	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
644851360	515	52.2	33	501	15	487	0.0e+00	621	COG0753	Catalase	496
644851361	257	41.38	1	255	3	251	1.0e-43	169	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644851363	209	38.46	3	208	2	208	1.0e-28	119	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644851364	177	41.57	1	177	4	181	3.0e-44	171	COG3038	Cytochrome b561	181
644851366	156	24.82	1	132	12	149	5.0e-08	50.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
644851367	162	54.94	1	162	1	161	2.0e-51	195	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
644851368	358	66.2	1	283	1	279	1.0e-88	319	COG0468	RecA/RadA recombinase	279
644851369	162	35.62	5	162	23	166	1.0e-25	109	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
644851370	875	58.92	1	875	4	879	0.0e+00	1202	COG0013	Alanyl-tRNA synthetase	879
644851371	61	67.21	1	61	1	61	1.0e-19	88	COG1551	sRNA-binding carbon storage regulator CsrA	73
644851376	188	38.17	4	185	1	185	1.0e-38	152	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
644851377	142	38.78	1	139	13	158	2.0e-22	98.4	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
644851378	520	67.64	1	514	1	515	0.0e+00	744	COG2918	Gamma-glutamylcysteine synthetase	518
644851379	171	64.2	1	162	1	161	8.0e-70	256	COG1854	S-ribosylhomocysteine lyase LuxS, autoinducer biosynthesis	161
644851380	264	54.75	1	262	2	262	2.0e-69	255	COG4137	ABC-type uncharacterized transport system, permease component	265
644851381	453	63.36	1	452	1	451	0.0e+00	642	COG0541	Signal recognition particle GTPase	451
644851382	82	59.76	1	82	1	81	2.0e-26	110	COG0228	Ribosomal protein S16	87
644851383	182	49.72	7	182	1	172	2.0e-55	208	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
644851384	251	58.26	1	241	1	240	1.0e-108	385	COG0336	tRNA G37 N-methylase TrmD	240
644851385	115	70.54	3	114	4	115	5.0e-42	162	COG0335	Ribosomal protein L19	115
644851388	354	62.46	2	349	1	348	0.0e+00	563	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
644851389	372	30.96	100	353	4	279	7.0e-56	211	COG0287	Prephenate dehydrogenase	279
644851390	393	42.14	112	389	4	279	2.0e-91	329	COG0077	Prephenate dehydratase	279
644851391	111	44.34	1	104	1	106	3.0e-28	116	COG1544	Ribosome-associated translation inhibitor RaiA	110
644851392	243	49.59	2	242	1	234	7.0e-67	247	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
644851393	325	46.2	6	303	1	289	2.0e-80	292	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644851394	246	52.82	5	246	1	248	4.0e-81	294	COG1496	Copper oxidase (laccase) domain	249
644851395	857	56.61	5	854	1	780	0.0e+00	996	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
644851401	263	40.07	1	260	41	305	4.0e-50	191	COG3021	Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily	309
644851402	465	23.93	61	249	52	285	9.0e-12	65.2	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
644851403	251	29.2	4	221	17	251	2.0e-21	96.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644851405	154	61.44	3	152	2	154	2.0e-55	208	COG0328	Ribonuclease HI	154
644851406	244	37.14	1	242	8	240	6.0e-47	180	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
644851408	320	46.2	6	320	23	348	8.0e-98	350	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
644851409	715	39.47	15	714	16	654	0.0e+00	631	COG0209	Ribonucleotide reductase alpha subunit	696
644851410	136	62.22	2	136	1	135	6.0e-50	189	COG1780	Protein involved in ribonucleotide reduction	141
644851411	77	33.78	1	70	1	74	2.0e-09	53.8	COG0695	Glutaredoxin	80
644851412	264	43.33	3	181	1	135	6.0e-38	151	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
644851413	287	52.48	3	283	1	280	2.0e-94	338	COG0421	Spermidine synthase	282
644851415	535	27.39	1	532	7	533	2.0e-48	187	COG1178	ABC-type Fe3+ transport system, permease component	540
644851416	354	34.27	4	346	3	352	2.0e-78	286	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644851419	177	63.84	1	177	3	177	7.0e-71	259	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
644851420	213	51.46	1	202	1	206	2.0e-64	238	COG0288	Carbonic anhydrase	207
644851421	307	38.41	1	301	1	292	2.0e-75	276	COG1131	ABC-type multidrug transport system, ATPase component	293
644851422	256	20.89	28	252	43	256	2.0e-08	53.2	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
644851423	126	57.6	2	126	1	125	1.0e-49	188	COG0853	Aspartate 1-decarboxylase	126
644851424	284	58.1	1	282	1	284	9.0e-112	396	COG0414	Panthothenate synthetase	285
644851425	264	58.71	3	264	1	264	2.0e-105	375	COG0413	Ketopantoate hydroxymethyltransferase	268
644851426	162	53.46	1	159	1	158	9.0e-51	192	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
644851428	151	54.17	32	151	1	120	3.0e-29	121	COG1734	RNA polymerase-binding transcription factor DksA	120
644851429	239	51.72	1	232	1	228	4.0e-83	301	COG1489	DNA-binding protein, stimulates sugar fermentation	235
644851430	177	32.96	6	175	2	179	1.0e-32	132	COG1514	2'-5' RNA ligase	180
644851431	825	42.82	5	823	50	845	0.0e+00	728	COG1643	HrpA-like RNA helicase	845
644851432	833	39.57	165	816	27	660	0.0e+00	567	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
644851433	426	66.35	3	426	6	429	0.0e+00	640	COG0001	Glutamate-1-semialdehyde aminotransferase	432
644851434	114	55.96	6	114	2	110	6.0e-39	152	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
644851435	272	27.07	24	269	50	314	1.0e-29	123	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
644851436	233	54.31	1	230	3	234	6.0e-66	244	COG0775	Nucleoside phosphorylase	234
644851437	505	33.4	2	505	1	412	2.0e-93	336	COG0232	dGTP triphosphohydrolase	412
644851438	482	41.24	7	393	1	345	2.0e-71	264	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
644851439	385	60.53	5	384	2	375	9.0e-126	443	COG3835	Sugar diacid utilization regulator	376
644851440	336	68.92	9	333	22	346	0.0e+00	514	COG1613	ABC-type sulfate transport system, periplasmic component	348
644851441	270	54.1	1	265	1	268	9.0e-69	253	COG0555	ABC-type sulfate transport system, permease component	274
644851442	294	56.1	2	288	4	286	1.0e-98	353	COG4208	ABC-type sulfate transport system, permease component	287
644851443	330	54.31	1	324	1	339	2.0e-111	395	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
644851444	433	33.49	1	425	1	428	6.0e-71	261	COG1455	Phosphotransferase system cellobiose-specific component IIC	432
644851446	314	33.68	217	310	25	119	1.0e-13	71	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644851448	322	27.92	61	317	66	312	1.0e-27	117	COG0657	Acetyl esterase/lipase	312
644851449	101	47.52	1	101	1	101	6.0e-26	108	COG1440	Phosphotransferase system cellobiose-specific component IIB	102
644851450	105	41.75	1	103	3	105	2.0e-22	97.2	COG1447	Phosphotransferase system cellobiose-specific component IIA	105
644851455	471	44.4	2	463	9	472	0.0e+00	520	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
644851456	422	61.76	1	421	6	424	0.0e+00	633	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
644851459	228	64.41	1	222	1	222	1.0e-104	372	COG0692	Uracil DNA glycosylase	223
644851460	127	84.25	1	127	1	127	8.0e-61	225	COG3445	Autonomous glycyl radical cofactor GrcA	127
644851461	450	42.07	1	446	26	476	1.0e-107	383	COG0513	Superfamily II DNA and RNA helicase	513
644851462	265	34.71	26	265	12	248	1.0e-55	209	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
644851463	534	58.81	11	532	9	508	0.0e+00	719	COG0029	Aspartate oxidase	518
644851464	191	37.1	7	191	2	181	5.0e-32	130	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644851465	221	54.17	1	216	5	213	9.0e-42	163	COG3073	Negative regulator of sigma E activity	213
644851466	316	53.46	1	314	1	318	3.0e-98	351	COG3026	Negative regulator of sigma E activity	320
644851467	156	51.68	1	149	1	149	3.0e-41	160	COG3086	Positive regulator of sigma E activity	150
644851468	599	70.9	1	597	6	603	0.0e+00	1087	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
644851470	226	54.59	1	224	3	230	1.0e-78	286	COG0571	dsRNA-specific ribonuclease	235
644851471	301	54.52	3	300	1	298	2.0e-117	415	COG1159	GTPase Era, involved in 16S rRNA processing	298
644851472	244	43.22	5	231	8	243	9.0e-55	207	COG1381	Recombinational DNA repair protein (RecF pathway)	251
644851473	243	67.9	4	243	1	243	5.0e-96	343	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
644851474	126	47.58	2	125	1	124	1.0e-36	144	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
644851476	258	26.78	34	254	18	248	5.0e-31	128	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644851477	505	45.25	321	498	4	181	3.0e-44	173	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644851479	726	32.46	27	715	12	696	0.0e+00	477	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
644851481	313	65.75	12	303	2	293	3.0e-119	421	COG2103	N-acetylmuramic acid 6-phosphate (MurNAc-6-P) etherase	298
644851482	168	58.22	5	149	6	151	6.0e-51	193	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
644851483	485	63.16	21	474	1	456	0.0e+00	615	COG4623	Membrane-bound lytic murein transglycosylase MltF	473
644851484	1295	38.88	159	964	1	730	0.0e+00	784	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
644851485	477	29.5	139	473	2	329	2.0e-35	144	COG0642	Signal transduction histidine kinase	336
644851487	445	45.57	3	445	1	463	0.0e+00	489	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644851488	112	75.89	1	112	1	112	5.0e-40	156	COG0347	Nitrogen regulatory protein PII	112
644851489	366	30	24	361	77	405	9.0e-57	214	COG4677	Pectin methylesterase and related acyl-CoA thioesterases	405
644851490	551	19.92	277	540	10	215	2.0e-06	48	COG2755	Lysophospholipase L1 or related esterase	216
644851491	385	31.51	25	385	21	344	3.0e-44	173	COG3866	Pectate lyase	345
644851492	405	27.79	26	405	5	344	5.0e-41	162	COG3866	Pectate lyase	345
644851493	392	31.05	47	392	35	344	4.0e-43	169	COG3866	Pectate lyase	345
644851494	395	60	1	148	1	150	1.0e-57	217	COG1017	Hemoglobin-like flavoprotein	150
644851495	417	70.7	5	416	4	412	0.0e+00	700	COG0112	Glycine/serine hydroxymethyltransferase	413
644851497	220	46.86	14	219	7	213	4.0e-61	227	COG3683	ABC-type uncharacterized transport system, periplasmic component	213
644851498	345	37.81	16	335	3	303	8.0e-61	227	COG2215	ABC-type nickel/cobalt efflux system, permease component RcnA	303
644851499	373	25.6	15	342	28	319	3.0e-41	163	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
644851500	263	41.5	6	254	3	254	3.0e-62	231	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
644851501	360	43.15	28	360	2	333	7.0e-53	201	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
644851502	374	25.99	21	342	29	317	1.0e-33	137	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
644851503	267	50.77	1	258	1	260	2.0e-82	298	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
644851504	249	51.43	1	245	1	242	1.0e-86	313	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
644851505	164	41.61	1	148	1	149	7.0e-39	153	COG1959	DNA-binding transcriptional regulator, IscR family	150
644851506	404	63.94	3	388	1	386	0.0e+00	579	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
644851507	128	51.72	1	126	5	146	4.0e-37	146	COG0822	NifU homolog involved in Fe-S cluster formation	150
644851508	107	58.33	1	107	3	110	2.0e-36	143	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
644851509	172	40.94	1	170	1	171	1.0e-25	109	COG1076	DnaJ-domain-containing proteins 1	174
644851510	616	47.24	19	602	5	579	0.0e+00	563	COG0443	Molecular chaperone DnaK (HSP70)	579
644851511	111	46.23	1	104	1	102	3.0e-20	90.5	COG0633	Ferredoxin	102
644851512	66	79.69	3	66	1	64	6.0e-23	98.9	COG2975	Fe-S-cluster formation regulator IscX/YfhJ	64
644851513	431	39.92	1	431	23	485	2.0e-124	439	COG0260	Leucyl aminopeptidase	485
644851515	284	42.45	8	284	11	283	9.0e-76	277	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
644851516	143	61.94	3	136	2	135	4.0e-55	206	COG0105	Nucleoside diphosphate kinase	135
644851517	392	57.75	25	376	1	349	0.0e+00	479	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
644851518	251	44.25	25	250	25	250	1.0e-52	199	COG3063	Tfp pilus assembly protein PilF	250
644851519	327	37.1	16	293	3	284	2.0e-48	186	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
644851520	373	62.33	7	367	1	361	0.0e+00	540	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
644851521	424	50	2	424	1	429	0.0e+00	515	COG0124	Histidyl-tRNA synthetase	429
644851522	206	51.22	1	204	1	205	4.0e-52	197	COG2976	Putative negative regulator of RcsB-dependent stress response	207
644851523	393	29.44	1	390	4	368	8.0e-48	184	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
644851524	497	52.52	1	473	2	444	0.0e+00	580	COG1160	Predicted GTPases	444
644851528	461	54.16	5	449	1	440	0.0e+00	539	COG1570	Exonuclease VII, large subunit	440
644851529	487	31.36	257	476	1	170	3.0e-34	139	COG0516	IMP dehydrogenase/GMP reductase	170
644851530	525	68.03	207	525	1	315	0.0e+00	553	COG0519	GMP synthase, PP-ATPase domain/subunit	315
644851532	418	22.98	84	387	1	303	3.0e-08	53.4	COG0582	Integrase	309
644851535	129	37.74	45	97	12	64	1.0e-07	48.8	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
644851537	103	58.25	1	100	3	104	3.0e-30	123	COG5489	Uncharacterized conserved protein, DUF736 family	107
644851539	502	24.8	9	501	20	412	5.0e-66	245	COG0232	dGTP triphosphohydrolase	412
644851540	340	28.48	3	330	1	302	6.0e-33	135	COG3547	Transposase	303
644851541	261	32.72	87	243	1	159	2.0e-12	66.6	COG5419	Uncharacterized protein	160
644851543	270	56.36	5	266	21	311	8.0e-69	253	COG5534	Plasmid replication initiator protein	383
644851544	243	46.81	3	237	16	250	6.0e-49	187	COG5314	Conjugal transfer/entry exclusion protein	252
644851545	387	34.25	1	378	27	452	5.0e-58	218	COG3846	Type IV secretory pathway, TrbL components	452
644851546	234	57.08	1	226	1	226	2.0e-83	301	COG3701	Type IV secretory pathway, TrbF components	228
644851547	293	35.11	77	293	41	256	1.0e-42	166	COG3504	Type IV secretory pathway, VirB9 components	265
644851548	412	34.51	15	406	3	360	4.0e-59	222	COG2948	Type IV secretory pathway, VirB10 components	360
644851549	103	31.96	3	99	2	95	4.0e-07	46.6	COG3668	Plasmid stabilization system protein ParE	98
644851551	133	59.06	7	133	1	127	9.0e-25	105	COG2916	DNA-binding protein H-NS	128
644851554	81	70.83	4	75	6	77	3.0e-22	97	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
644851557	1423	22.18	561	1311	11	669	7.0e-35	143	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
644851558	135	34.31	1	131	3	139	4.0e-26	110	COG5435	Uncharacterized protein	147
644851559	617	44.06	1	544	6	550	0.0e+00	559	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
644851560	172	44.77	1	172	1	160	2.0e-50	191	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
644851563	215	24.73	21	206	17	196	3.0e-08	52.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644851565	297	25.9	1	296	3	301	3.0e-43	168	COG0492	Thioredoxin reductase	305
644851566	125	28.38	25	96	1	74	4.0e-06	43.4	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
644851567	128	24.62	1	127	5	132	9.0e-13	65.7	COG0824	Acyl-CoA thioesterase FadM	137
644851568	136	44.55	1	101	3	103	2.0e-25	108	COG1733	DNA-binding transcriptional regulator, HxlR family	120
644851570	211	40.87	1	204	4	207	3.0e-51	195	COG0288	Carbonic anhydrase	207
644851571	319	58.39	157	317	1	160	5.0e-56	211	COG3272	Uncharacterized conserved protein YbgA, DUF1722 family	163
644851572	406	44.76	120	405	3	283	7.0e-84	304	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
644851573	247	36.03	4	240	8	247	1.0e-53	203	COG3496	Uncharacterized conserved protein, DUF1365 family	261
644851574	420	41.67	1	416	9	425	6.0e-121	427	COG2907	Predicted NAD/FAD-binding protein	447
644851575	239	24.9	1	238	6	257	2.0e-28	119	COG0300	Short-chain dehydrogenase	265
644851577	242	29.67	3	93	1	91	7.0e-13	67.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
644851579	239	55.07	7	233	4	229	2.0e-69	255	COG3819	Uncharacterized membrane protein	229
644851580	328	50.92	3	328	1	313	9.0e-87	313	COG3817	Uncharacterized membrane protein	313
644851582	130	19.86	1	125	2	137	6.0e-07	46.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644851583	222	35.65	7	221	6	221	3.0e-41	161	COG0765	ABC-type amino acid transport system, permease component	222
644851584	241	47.48	2	239	1	237	2.0e-79	288	COG1126	ABC-type polar amino acid transport system, ATPase component	240
644851585	233	33.99	12	213	17	219	5.0e-37	147	COG0765	ABC-type amino acid transport system, permease component	222
644851586	252	24.51	6	252	12	264	2.0e-26	113	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644851587	264	55.25	11	264	1	257	4.0e-73	268	COG2145	Hydroxyethylthiazole kinase, sugar kinase family	265
644851588	267	50.94	1	267	1	263	2.0e-93	335	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
644851589	284	24.73	36	284	1	274	1.0e-22	100	COG1082	Sugar phosphate isomerase/epimerase	274
644851590	326	38.11	1	325	1	328	3.0e-76	278	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644851591	384	26.94	1	384	3	342	2.0e-50	193	COG0673	Predicted dehydrogenase	342
644851592	356	26.06	20	324	13	273	3.0e-29	123	COG1082	Sugar phosphate isomerase/epimerase	274
644851594	259	31.78	4	257	3	259	1.0e-59	223	COG3622	Hydroxypyruvate isomerase	260
644851595	135	66.67	10	135	12	137	1.0e-31	128	COG3223	Phosphate starvation-inducible membrane PsiE (function unknown)	138
644851596	458	42.17	1	394	4	347	9.0e-112	397	COG0826	Collagenase-like protease, PrtC family	347
644851597	320	50.46	1	312	1	324	8.0e-111	393	COG0435	Glutathionyl-hydroquinone reductase	324
644851598	243	48.68	16	239	3	229	2.0e-61	228	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644851599	452	34.11	151	450	35	330	2.0e-40	160	COG0642	Signal transduction histidine kinase	336
644851600	467	20.78	5	413	8	359	1.0e-12	67.9	COG2814	Predicted arabinose efflux permease, MFS family	394
644851601	1029	38.72	2	1011	1	1009	0.0e+00	967	COG0841	Multidrug efflux pump subunit AcrB	1009
644851602	1046	38.68	19	1031	3	1009	0.0e+00	960	COG0841	Multidrug efflux pump subunit AcrB	1009
644851603	419	35.52	60	390	37	367	1.0e-33	137	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644851604	393	46.77	3	393	2	403	2.0e-110	392	COG1972	Nucleoside permease NupC	404
644851605	320	46.88	8	320	4	309	8.0e-81	294	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
644851606	355	27.05	140	346	1	190	3.0e-27	116	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
644851607	164	51.18	1	164	1	169	1.0e-40	158	COG5404	Cell division inhibitor SulA, prevents FtsZ ring assembly	169
644851608	209	37.19	2	121	1	121	1.0e-17	83	COG3070	Transcriptional regulator of competence genes, TfoX/Sxy family	121
644851609	731	35.28	9	703	2	658	5.0e-112	399	COG1289	Uncharacterized membrane protein YccC	674
644851610	148	69.18	1	146	1	145	3.0e-52	197	COG3304	Uncharacterized membrane protein YccF, DUF307 family	145
644851612	152	68.09	8	148	1	141	1.0e-62	232	COG1803	Methylglyoxal synthase	142
644851613	215	38.43	6	213	4	216	8.0e-38	150	COG3110	Uncharacterized conserved protein YccT, UPF0319 family	216
644851614	137	60.58	1	137	4	140	2.0e-49	187	COG1832	Predicted CoA-binding protein	140
644851615	102	38.68	1	102	10	114	1.0e-25	107	COG3785	Heat shock protein HspQ	116
644851616	92	51.61	1	92	1	92	9.0e-24	101	COG1254	Acylphosphatase	92
644851617	109	79.82	1	109	3	111	2.0e-48	183	COG2920	Sulfur relay (sulfurtransferase) protein, DsrC/TusE family	111
644851618	219	35.37	1	219	4	232	1.0e-26	113	COG0670	Integral membrane protein, interacts with FtsH	233
644851623	385	20.69	1	385	9	382	3.0e-12	66.7	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
644851626	174	24.57	3	140	7	181	2.0e-12	65.2	COG1335	Nicotinamidase-related amidase	205
644851628	143	34	1	143	3	151	8.0e-15	73.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
644851630	509	47.26	11	497	2	492	0.0e+00	511	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
644851631	689	50.79	2	685	6	692	0.0e+00	868	COG0855	Polyphosphate kinase	696
644851632	743	43.01	1	739	2	733	0.0e+00	653	COG4590	ABC-type uncharacterized transport system, permease component	733
644851633	548	33.7	1	271	8	280	1.0e-63	238	COG4985	ABC-type phosphate transport system, auxiliary component	289
644851634	271	70.08	18	271	1	253	7.0e-124	436	COG1117	ABC-type phosphate transport system, ATPase component	253
644851636	456	50.18	171	451	1	262	1.0e-88	321	COG1760	L-serine deaminase	262
644851637	427	37.23	17	426	7	412	2.0e-73	270	COG0814	Amino acid permease	415
644851638	356	44.59	1	350	1	375	1.0e-116	413	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
644851639	169	65.03	7	169	2	162	2.0e-58	218	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
644851640	240	53.33	4	240	1	236	4.0e-73	267	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
644851641	164	51.2	1	164	1	158	4.0e-52	196	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
644851642	143	30.25	20	136	17	133	6.0e-07	46.9	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
644851643	461	60.3	1	461	1	464	0.0e+00	705	COG0215	Cysteinyl-tRNA synthetase	464
644851644	70	42.86	1	70	1	70	7.0e-19	85.2	COG2501	Ribosome-associated protein YbcJ, S4-like RNA binding protein	73
644851645	289	59.01	4	286	1	283	7.0e-115	406	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
644851646	646	32.55	275	632	23	406	3.0e-41	163	COG0840	Methyl-accepting chemotaxis protein	408
644851647	266	40.82	1	264	6	271	3.0e-72	265	COG3741	N-formylglutamate amidohydrolase	272
644851648	404	41.83	5	402	3	399	5.0e-96	345	COG1228	Imidazolonepropionase or related amidohydrolase	406
644851649	454	28.89	46	441	53	421	3.0e-56	212	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
644851651	285	27.49	1	285	3	269	5.0e-30	124	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644851652	240	47.16	7	233	1	229	1.0e-56	213	COG4215	ABC-type arginine transport system, permease component	230
644851653	238	51.54	3	228	2	228	3.0e-58	218	COG4160	ABC-type arginine/histidine transport system, permease component	228
644851654	260	66.27	3	257	1	255	4.0e-111	394	COG4598	ABC-type histidine transport system, ATPase component	256
644851655	523	49.8	8	496	7	496	0.0e+00	586	COG2986	Histidine ammonia-lyase	498
644851656	247	33.47	14	247	1	236	2.0e-54	205	COG2188	DNA-binding transcriptional regulator, GntR family	236
644851658	518	58.91	9	502	6	498	0.0e+00	602	COG2986	Histidine ammonia-lyase	498
644851659	563	75.76	6	562	3	555	0.0e+00	957	COG2987	Urocanate hydratase	561
644851660	228	31.05	9	226	13	230	5.0e-37	147	COG1802	DNA-binding transcriptional regulator, GntR family	230
644851661	490	49.79	12	488	1	473	0.0e+00	538	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
644851663	340	34.66	1	337	1	350	6.0e-70	258	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
644851664	404	32.38	9	389	23	371	5.0e-81	295	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644851669	369	54.37	1	355	1	338	9.0e-130	456	COG3839	ABC-type sugar transport system, ATPase component	338
644851670	417	42.39	26	415	39	420	4.0e-101	361	COG2182	Maltose-binding periplasmic protein MalE	420
644851671	435	34.31	125	430	1	291	2.0e-56	213	COG1175	ABC-type sugar transport system, permease component	295
644851672	299	50	21	299	3	282	5.0e-91	327	COG3833	ABC-type maltose transport system, permease component	282
644851673	399	53.25	1	399	2	392	0.0e+00	516	COG3867	Arabinogalactan endo-1,4-beta-galactosidase	403
644851674	685	42.57	2	682	4	672	0.0e+00	669	COG1874	Beta-galactosidase GanA	673
644851675	104	36.36	25	99	1	77	3.0e-12	63.4	COG1264	Phosphotransferase system IIB components	88
644851676	423	40.55	1	423	1	429	8.0e-109	387	COG4580	Maltoporin (phage lambda and maltose receptor)	429
644851677	357	33.23	6	334	1	332	4.0e-67	248	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644851679	373	54.67	1	373	9	383	9.0e-122	430	COG2850	Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain	383
644851680	109	36.73	13	109	8	105	1.0e-07	48.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
644851681	307	29.39	3	294	2	292	2.0e-30	126	COG0583	DNA-binding transcriptional regulator, LysR family	297
644851682	170	48.84	40	168	1	120	5.0e-35	140	COG4922	Predicted SnoaL-like aldol condensation-catalyzing enzyme	129
644851683	395	24.53	74	383	15	306	6.0e-46	178	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
644851684	491	37.36	311	490	1	181	3.0e-41	163	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644851688	814	27.37	1	796	15	808	1.0e-93	338	COG3264	Small-conductance mechanosensitive channel	835
644851689	286	38.79	3	277	2	276	5.0e-63	234	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
644851690	407	41.28	14	395	5	390	7.0e-106	377	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
644851693	272	24.42	30	268	28	275	1.0e-29	123	COG3031	Type II secretory pathway, component PulC	275
644851694	716	29.74	13	669	18	563	2.0e-88	320	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
644851695	498	54.08	10	497	15	500	0.0e+00	565	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
644851696	408	43.73	1	407	1	397	6.0e-100	357	COG1459	Type II secretory pathway, component PulF	397
644851697	153	40.69	3	136	5	149	2.0e-22	98.2	COG2165	Type II secretory pathway, pseudopilin PulG	149
644851700	246	31.44	2	193	3	190	8.0e-29	120	COG4795	Type II secretory pathway, component PulJ	194
644851701	356	32.67	1	345	1	312	6.0e-48	185	COG3156	Type II secretory pathway, component PulK	323
644851702	400	26.4	8	397	2	388	3.0e-47	182	COG3297	Type II secretory pathway, component PulL	390
644851703	162	33.76	4	160	24	179	7.0e-17	80.1	COG3149	Type II secretory pathway, component PulM	181
644851704	283	45.56	13	281	2	247	3.0e-33	135	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
644851706	190	41.86	18	182	4	175	3.0e-40	158	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
644851708	352	42.7	1	352	3	360	5.0e-88	318	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
644851709	138	32.12	1	136	1	137	3.0e-28	117	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
644851710	252	35.63	5	249	1	251	9.0e-38	150	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644851711	291	67.13	1	216	1	216	2.0e-90	325	COG1535	Isochorismate hydrolase	218
644851712	542	63.48	1	530	4	535	0.0e+00	736	COG1021	Non-ribosomal peptide synthetase component E (peptide arylation enzyme)	542
644851713	395	43.95	19	389	44	423	1.0e-108	386	COG1169	Isochorismate synthase EntC	423
644851714	740	25.89	25	739	23	718	1.0e-66	248	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
644851715	430	34.46	132	424	17	296	9.0e-50	191	COG2382	Enterochelin esterase or related enzyme	299
644851716	72	62.12	7	72	4	69	6.0e-20	88.9	COG3251	Uncharacterized conserved protein YbdZ, MbtH family	71
644851717	2877	40.39	1812	2460	2	642	1.0e-118	423	COG1020	Non-ribosomal peptide synthetase component F	642
644851719	265	49.42	4	260	2	258	3.0e-94	337	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
644851720	344	56.23	1	344	1	345	3.0e-77	282	COG4779	ABC-type enterobactin transport system, permease component	346
644851721	358	45.45	33	356	1	329	1.0e-53	203	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
644851722	424	21.28	21	403	13	389	3.0e-07	50.2	COG2814	Predicted arabinose efflux permease, MFS family	394
644851723	348	53.87	21	343	7	319	3.0e-101	362	COG4592	ABC-type Fe2+-enterobactin transport system, periplasmic component	319
644851727	269	44.53	1	269	2	274	3.0e-69	255	COG2503	Predicted secreted acid phosphatase	274
644851729	257	36.73	64	207	48	190	1.0e-21	96.9	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
644851731	253	53.78	4	251	6	249	2.0e-78	285	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
644851732	523	38.08	25	499	1	429	4.0e-113	402	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
644851733	417	48.42	3	417	1	440	9.0e-115	407	COG2067	Long-chain fatty acid transport protein	440
644851734	98	67.35	1	98	1	98	1.0e-28	117	COG3691	Uncharacterized conserved protein YfcZ, UPF0381/DUF406 family	98
644851735	439	33.72	14	437	1	391	1.0e-59	224	COG0183	Acetyl-CoA acetyltransferase	392
644851736	732	43.66	321	600	2	284	2.0e-82	301	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
644851737	161	38.27	1	156	2	162	1.0e-32	132	COG2062	Phosphohistidine phosphatase SixA	163
644851738	181	51.93	1	176	1	181	4.0e-52	197	COG2840	DNA-nicking endonuclease, Smr domain	184
644851739	310	41.38	14	301	1	279	4.0e-66	245	COG2890	Methylase of polypeptide chain release factors	280
644851740	361	61.04	2	361	1	366	0.0e+00	545	COG0082	Chorismate synthase	369
644851741	269	58.46	1	269	10	281	3.0e-103	368	COG3770	Murein endopeptidase	284
644851742	266	35.69	7	255	3	256	6.0e-20	91.6	COG0730	Uncharacterized membrane protein YfcA	258
644851743	187	77.97	11	187	3	179	6.0e-86	309	COG3101	Elongation factor P hydroxylase (EF-P beta-lysylation pathway)	180
644851745	303	27.8	1	294	1	293	9.0e-28	117	COG0583	DNA-binding transcriptional regulator, LysR family	297
644851746	472	35.35	4	445	32	468	1.0e-89	324	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644851747	225	31.25	20	225	11	183	2.0e-20	92.9	COG0693	Putative intracellular protease/amidase	188
644851748	209	26.79	5	209	4	209	2.0e-23	102	COG0625	Glutathione S-transferase	211
644851749	141	52.82	1	140	1	142	3.0e-42	164	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
644851750	105	27.18	1	103	5	107	3.0e-11	59.8	COG4392	Branched-chain amino acid transport protein	107
644851751	246	33.33	13	239	3	233	2.0e-30	125	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
644851752	277	33.33	156	277	1	123	3.0e-21	96.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644851753	672	41.98	1	243	1	240	2.0e-82	300	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
644851754	406	46	1	404	2	411	3.0e-118	418	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644851756	505	55.18	1	501	1	500	0.0e+00	565	COG3333	TctA family transporter	504
644851758	325	38.04	1	325	1	319	5.0e-79	287	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
644851759	224	44.93	1	218	1	226	8.0e-49	187	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644851760	463	32.91	150	458	20	327	4.0e-34	139	COG0642	Signal transduction histidine kinase	336
644851761	377	36.7	1	295	2	323	3.0e-56	212	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
644851762	336	43.15	4	331	1	334	4.0e-92	331	COG0136	Aspartate-semialdehyde dehydrogenase	334
644851763	276	53.26	14	274	3	263	2.0e-93	335	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
644851764	221	41.46	15	218	1	203	9.0e-38	150	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
644851765	303	66.2	1	285	1	287	3.0e-123	434	COG0777	Acetyl-CoA carboxylase beta subunit	294
644851766	422	47.04	7	416	1	423	1.0e-129	457	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
644851767	285	43.71	1	283	1	226	9.0e-29	120	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
644851768	163	44.79	1	162	1	163	2.0e-28	118	COG1286	Uncharacterized membrane protein, required for colicin V production	182
644851769	505	55.1	1	485	4	470	0.0e+00	641	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
644851770	189	62.11	1	188	2	188	7.0e-77	279	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
644851771	259	32.97	1	259	1	270	7.0e-38	150	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644851772	229	55.26	1	225	2	229	9.0e-76	276	COG4215	ABC-type arginine transport system, permease component	230
644851773	238	59.29	7	232	1	226	3.0e-80	291	COG4160	ABC-type arginine/histidine transport system, permease component	228
644851774	257	79.6	4	253	5	253	9.0e-117	413	COG4598	ABC-type histidine transport system, ATPase component	256
644851775	302	55.25	3	297	1	294	1.0e-113	402	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
644851776	209	34.62	1	202	1	201	5.0e-36	144	COG0625	Glutathione S-transferase	211
644851777	183	40	1	167	2	158	1.0e-37	149	COG0622	Predicted phosphodiesterase	172
644851778	203	19.79	10	188	3	185	1.0e-07	49.9	COG1443	Isopentenyldiphosphate isomerase	185
644851779	713	57.06	391	711	1	325	4.0e-117	416	COG0280	Phosphotransacetylase	327
644851780	400	56.28	4	399	1	393	0.0e+00	572	COG0282	Acetate kinase	396
644851781	151	73.15	3	151	1	149	6.0e-60	222	COG3092	Uncharacterized membrane protein YfbV, UPF0208 family	149
644851782	164	80.49	1	164	5	168	4.0e-75	273	COG3013	Uncharacterized protein YfbU, UPF0304 family	168
644851783	218	38.1	3	207	2	211	9.0e-39	153	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
644851784	611	20.51	22	611	1	458	2.0e-47	183	COG0471	Di- and tricarboxylate transporter	461
644851785	199	40.1	1	195	3	193	2.0e-43	168	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
644851786	404	37.38	8	402	1	392	4.0e-97	348	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
644851788	309	27.96	11	275	1	277	3.0e-30	125	COG0583	DNA-binding transcriptional regulator, LysR family	297
644851789	147	44.26	4	125	1	122	2.0e-33	134	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
644851790	224	56.78	17	214	1	194	6.0e-73	267	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
644851791	599	57.14	201	599	1	398	0.0e+00	609	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
644851792	176	46.79	21	176	2	157	3.0e-57	214	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
644851793	449	57.28	4	429	2	423	0.0e+00	648	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
644851794	908	37.58	1	783	1	693	0.0e+00	711	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
644851795	324	54.41	1	322	1	329	7.0e-103	367	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
644851796	180	42.68	10	172	12	170	3.0e-40	157	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
644851797	183	38.65	1	163	4	166	2.0e-24	105	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
644851798	100	61	1	100	1	100	4.0e-26	109	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
644851799	616	43.09	4	612	1	606	5.0e-122	432	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
644851800	532	50.59	20	525	2	493	0.0e+00	515	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
644851801	485	45.3	4	481	1	470	7.0e-98	351	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
644851802	730	19.94	72	717	26	449	3.0e-46	180	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
644851803	293	39.13	2	293	1	291	2.0e-58	219	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
644851804	530	43.18	1	530	3	530	0.0e+00	586	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644851805	375	49.46	1	368	1	354	2.0e-119	422	COG1740	Ni,Fe-hydrogenase I small subunit	355
644851806	338	32.46	37	227	11	173	9.0e-37	147	COG0437	Fe-S-cluster-containing dehydrogenase component	203
644851807	399	53.6	3	390	2	399	4.0e-89	321	COG5557	Ni/Fe-hydrogenase 2 integral membrane subunit HybB	401
644851808	568	54.66	2	568	1	545	0.0e+00	664	COG0374	Ni,Fe-hydrogenase I large subunit	545
644851809	166	38.99	1	157	2	160	2.0e-31	128	COG0680	Ni,Fe-hydrogenase maturation factor	160
644851811	114	53.51	1	114	1	113	3.0e-32	130	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
644851812	394	46.63	177	380	1	201	6.0e-69	254	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
644851813	95	56	1	75	1	71	5.0e-20	89.2	COG0298	Hydrogenase maturation factor	82
644851814	371	57.03	1	369	1	363	0.0e+00	507	COG0409	Hydrogenase maturation factor	364
644851815	342	52.02	8	342	1	339	9.0e-99	353	COG0309	Hydrogenase maturation factor	339
644851816	329	28.53	3	314	2	303	5.0e-17	81.9	COG3547	Transposase	303
644851817	766	46.73	12	763	1	750	0.0e+00	833	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
644851819	241	36.07	34	214	11	190	6.0e-38	151	COG0518	GMP synthase - Glutamine amidotransferase domain	198
644851820	472	35.29	1	472	1	457	3.0e-105	375	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644851822	1016	27.52	2	735	1	598	8.0e-97	349	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
644851823	300	46.12	21	238	2	202	1.0e-58	220	COG0437	Fe-S-cluster-containing dehydrogenase component	203
644851824	211	56.25	1	205	1	208	3.0e-65	241	COG2864	Cytochrome b subunit of formate dehydrogenase	218
644851825	329	28.53	3	314	2	303	5.0e-17	81.9	COG3547	Transposase	303
644851826	432	19.67	14	428	21	437	3.0e-20	93.3	COG2271	Sugar phosphate permease	448
644851827	311	62.14	1	304	1	305	1.0e-106	379	COG3058	Formate dehydrogenase maturation protein FdhE	308
644851830	545	26.3	30	544	2	549	6.0e-72	265	COG3507	Beta-xylosidase	549
644851833	432	29.05	16	369	2	335	6.0e-52	198	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
644851834	310	36.29	51	305	1	250	1.0e-45	176	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
644851835	264	45.56	5	263	2	248	2.0e-87	315	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
644851836	1386	48.03	414	1222	1	793	0.0e+00	972	COG1251	NAD(P)H-nitrite reductase, large subunit	793
644851837	882	32.61	5	692	42	763	3.0e-127	449	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
644851838	276	52.28	18	258	1	239	2.0e-81	295	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
644851839	181	37.57	5	181	2	175	3.0e-31	128	COG0431	NAD(P)H-dependent FMN reductase	184
644851844	258	33.46	1	255	4	268	5.0e-35	141	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644851845	391	34.49	26	391	23	393	1.0e-84	306	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
644851846	319	26.51	31	319	1	296	7.0e-27	114	COG0583	DNA-binding transcriptional regulator, LysR family	297
644851847	338	36.94	6	336	2	313	1.0e-77	283	COG1619	Muramoyltetrapeptide carboxypeptidase LdcA (peptidoglycan recycling)	313
644851848	532	35.05	130	509	1	408	3.0e-48	186	COG0840	Methyl-accepting chemotaxis protein	408
644851850	587	48.85	27	587	10	539	0.0e+00	621	COG0405	Gamma-glutamyltranspeptidase	539
644851851	415	20.35	1	389	2	381	2.0e-33	137	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
644851853	187	24.34	1	186	5	193	2.0e-11	62.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644851854	367	35.4	6	340	33	358	9.0e-28	117	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644851855	480	38.18	16	476	1	456	2.0e-57	216	COG1538	Outer membrane protein TolC	457
644851856	383	31.76	116	366	9	250	2.0e-39	157	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
644851857	326	41.9	1	325	1	315	1.0e-85	309	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
644851862	411	22.43	20	395	4	324	7.0e-35	141	COG0270	Site-specific DNA-cytosine methylase	328
644851864	314	47.62	30	312	2	295	2.0e-77	282	COG4227	Antirestriction protein ArdC	316
644851865	78	45	1	78	1	80	1.0e-12	64.7	COG5302	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid	80
644851870	338	29.07	1	311	3	292	6.0e-45	174	COG0630	Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase	312
644851871	400	22.81	30	394	4	360	9.0e-34	138	COG2948	Type IV secretory pathway, VirB10 components	360
644851872	296	19.39	21	281	27	245	8.0e-18	84.7	COG3504	Type IV secretory pathway, VirB9 components	265
644851873	227	31.22	6	223	20	232	1.0e-29	123	COG3736	Type IV secretory pathway, component VirB8	239
644851875	342	21.41	32	319	72	393	7.0e-06	45	COG3704	Type IV secretory pathway, VirB6 components	406
644851878	915	32.68	112	911	18	788	1.0e-130	461	COG3451	Type IV secretory pathway, VirB4 component	796
644851884	402	50.64	10	400	1	379	2.0e-110	392	COG3328	Transposase (or an inactivated derivative)	379
644851887	64	54.1	1	61	8	68	5.0e-16	76.1	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
644851890	95	63.64	4	80	6	82	6.0e-22	95.5	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
644851892	172	44.77	1	172	1	160	2.0e-50	191	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
644851893	617	43.69	1	544	6	550	0.0e+00	558	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
644851894	135	35.04	1	131	3	139	5.0e-26	110	COG5435	Uncharacterized protein	147
644851895	1457	20.97	576	1352	11	695	8.0e-35	143	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
644851899	103	56.6	1	103	3	107	2.0e-32	130	COG5489	Uncharacterized conserved protein, DUF736 family	107
644851900	90	70.27	11	84	7	80	1.0e-22	98.2	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
644851903	423	19.8	103	401	27	309	1.0e-10	61.5	COG0582	Integrase	309
644851906	469	53.91	17	463	11	454	0.0e+00	523	COG1113	L-asparagine transporter and related permeases	462
644851909	220	41.78	2	213	1	211	4.0e-52	197	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644851910	610	51.49	5	608	3	581	0.0e+00	682	COG0322	Excinuclease UvrABC, nuclease subunit	581
644851911	182	41.21	1	181	10	190	5.0e-29	120	COG0558	Phosphatidylglycerophosphate synthase	192
644851919	163	41.51	7	163	29	179	2.0e-34	138	COG4678	Muramidase (phage lambda lysozyme)	180
644851923	125	37.11	26	122	3	98	5.0e-08	50	COG3783	Soluble cytochrome b562	100
644851924	478	33.04	23	476	9	455	5.0e-66	245	COG0534	Na+-driven multidrug efflux pump	455
644851927	574	36.36	149	530	3	408	3.0e-50	193	COG0840	Methyl-accepting chemotaxis protein	408
644851930	295	47.89	1	284	3	265	6.0e-73	267	COG1291	Flagellar motor component MotA	266
644851931	376	38.31	7	265	1	244	3.0e-53	202	COG1360	Flagellar motor protein MotB	244
644851932	672	44.08	1	664	6	711	0.0e+00	654	COG0643	Chemotaxis protein histidine kinase CheA	716
644851933	165	46.31	13	161	14	162	4.0e-37	147	COG0835	Chemotaxis signal transduction protein	165
644851934	566	39.95	166	518	31	408	5.0e-54	205	COG0840	Methyl-accepting chemotaxis protein	408
644851935	290	51.46	27	289	1	268	3.0e-79	288	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
644851936	350	58.67	3	344	1	345	4.0e-119	421	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
644851938	214	68.2	1	214	1	217	1.0e-76	279	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
644851939	383	48.21	1	363	1	363	1.0e-128	453	COG1377	Flagellar biosynthesis protein FlhB	363
644851940	698	60.23	2	695	1	696	0.0e+00	928	COG1298	Flagellar biosynthesis pathway, component FlhA	696
644851942	145	42.76	1	145	2	146	8.0e-24	102	COG3418	Flagellar biosynthesis/type III secretory pathway chaperone	146
644851943	99	43.16	1	95	1	93	6.0e-11	59.2	COG2747	Negative regulator of flagellin synthesis (anti-sigma28 factor)	93
644851944	222	38.5	10	221	8	219	5.0e-41	160	COG1261	Flagella basal body P-ring formation protein FlgA	220
644851945	139	46.72	2	137	1	133	4.0e-34	137	COG1815	Flagellar basal body rod protein FlgB	133
644851946	134	71.53	1	134	1	137	2.0e-48	184	COG1558	Flagellar basal body rod protein FlgC	137
644851947	223	44.39	1	223	1	222	3.0e-41	161	COG1843	Flagellar hook assembly protein FlgD	222
644851948	405	47.27	1	405	3	422	8.0e-86	311	COG1749	Flagellar hook protein FlgE	423
644851949	251	65.34	1	251	1	251	8.0e-90	323	COG4787	Flagellar basal body rod protein FlgF	251
644851950	260	55.68	1	260	1	263	8.0e-85	306	COG4786	Flagellar basal body rod protein FlgG	265
644851951	239	54.39	14	236	3	230	3.0e-67	248	COG2063	Flagellar basal body L-ring protein FlgH	230
644851952	369	61.6	8	369	7	365	2.0e-124	439	COG1706	Flagellar basal body P-ring protein FlgI	365
644851953	317	42.29	143	317	33	201	8.0e-44	170	COG1705	Flagellum-specific peptidoglycan hydrolase FlgJ	201
644851954	640	33.33	1	497	3	486	1.0e-69	258	COG1256	Flagellar hook-associated protein FlgK	552
644851955	309	18.11	1	309	1	358	6.0e-20	91.7	COG1344	Flagellin and related hook-associated protein FlgL	360
644851956	260	47.41	9	259	8	258	2.0e-47	182	COG1684	Flagellar biosynthesis protein FliR	258
644851957	89	55.06	1	89	1	89	3.0e-19	86.7	COG1987	Flagellar biosynthesis protein FliQ	89
644851958	258	55.92	15	257	4	248	4.0e-77	281	COG1338	Flagellar biosynthetic protein FliP	248
644851959	138	36.88	1	138	2	135	2.0e-23	101	COG3190	Flagellar biogenesis protein FliO	137
644851960	138	44.96	1	126	8	136	5.0e-24	103	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
644851961	338	48.52	1	335	1	331	2.0e-100	359	COG1868	Flagellar motor switch protein FliM	332
644851962	162	37.82	8	162	9	159	1.0e-33	135	COG1580	Flagellar basal body-associated protein FliL	159
644851963	443	24.15	3	443	2	417	9.0e-18	85.1	COG3144	Flagellar hook-length control protein FliK	417
644851964	146	44.83	1	145	1	145	2.0e-18	85.3	COG2882	Flagellar biosynthesis chaperone FliJ	148
644851965	456	59.33	4	453	1	440	0.0e+00	626	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
644851966	251	34.38	64	251	43	229	2.0e-39	156	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
644851967	330	51.96	1	330	9	339	2.0e-89	322	COG1536	Flagellar motor switch protein FliG	339
644851968	568	43.84	12	567	9	545	0.0e+00	482	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
644851969	104	42.45	1	104	2	105	5.0e-12	62.6	COG1677	Flagellar hook-basal body complex protein FliE	105
644851971	136	49.61	1	127	1	122	2.0e-32	131	COG1516	Flagellin-specific chaperone FliS	132
644851972	473	36.19	25	472	12	483	3.0e-46	179	COG1345	Flagellar capping protein FliD	483
644851973	275	34.09	3	266	2	263	2.0e-23	102	COG1344	Flagellin and related hook-associated protein FlgL	360
644851974	1144	27.72	661	1131	148	618	1.0e-59	225	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
644851975	374	36.6	1	371	2	373	8.0e-93	334	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
644851977	375	25.68	8	375	1	340	7.0e-35	141	COG0673	Predicted dehydrogenase	342
644851980	345	19.26	22	154	1	134	7.0e-08	51.9	COG3415	Transposase	138
644851982	240	45.99	5	239	17	247	9.0e-61	226	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
644851985	262	45.95	4	262	81	329	4.0e-76	277	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
644851986	534	36.63	193	511	66	408	3.0e-40	160	COG0840	Methyl-accepting chemotaxis protein	408
644851989	212	28.12	1	160	1	151	2.0e-32	132	COG0698	Ribose 5-phosphate isomerase RpiB	151
644851990	172	36.08	13	168	1	147	2.0e-38	151	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
644851991	576	37.88	6	570	30	646	0.0e+00	502	COG1067	Predicted ATP-dependent protease	647
644851992	157	73.83	1	149	1	149	8.0e-54	202	COG3120	Macrodomain Ter protein organizer, MatP/YcbG family	149
644851995	554	36.76	131	513	1	408	1.0e-44	174	COG0840	Methyl-accepting chemotaxis protein	408
644851996	495	28.48	38	492	2	437	5.0e-45	175	COG3182	Uncharacterized iron-regulated membrane protein	442
644851997	522	58.94	16	522	25	530	0.0e+00	740	COG3131	Periplasmic glucans biosynthesis protein	534
644851998	849	65.42	64	839	1	734	0.0e+00	1007	COG2943	Membrane glycosyltransferase	736
644851999	306	52.29	4	306	3	307	5.0e-94	337	COG1560	Lauroyl/myristoyl acyltransferase	308
644852000	353	41.88	20	339	1	308	8.0e-99	354	COG1054	Predicted sulfurtransferase	308
644852001	192	42.05	1	192	1	192	5.0e-47	180	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
644852002	184	44.69	3	181	1	179	8.0e-45	173	COG3038	Cytochrome b561	181
644852005	347	66.67	8	346	5	343	0.0e+00	556	COG0418	Dihydroorotase	344
644852006	95	34.38	1	95	2	97	1.0e-16	78.1	COG1359	Quinol monooxygenase YgiN	100
644852007	1058	55.87	1	493	1	487	0.0e+00	568	COG1530	Ribonuclease G or E	487
644852008	320	45	8	304	1	289	3.0e-77	281	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644852009	200	44.56	7	198	2	192	1.0e-58	219	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
644852010	173	41.01	1	173	1	176	4.0e-34	137	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
644852011	56	49.12	1	56	1	57	2.0e-11	60.3	COG0333	Ribosomal protein L32	57
644852012	348	52.46	3	347	1	338	3.0e-122	431	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
644852013	316	56.39	1	316	2	322	7.0e-116	410	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
644852014	309	57.1	1	309	1	310	3.0e-106	378	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
644852015	244	47.43	1	241	1	250	5.0e-49	188	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644852016	78	64.1	1	78	3	80	4.0e-12	63	COG0236	Acyl carrier protein	80
644852017	412	57.97	2	412	1	411	0.0e+00	485	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644852018	267	27.68	1	261	3	272	4.0e-45	175	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
644852019	343	46.39	1	330	6	337	1.0e-111	396	COG1559	Cell division protein YceG, involved in septum cleavage	342
644852020	215	49.04	2	207	1	205	6.0e-57	213	COG0125	Thymidylate kinase	208
644852022	264	52.69	1	256	1	256	1.0e-81	296	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
644852023	477	39	1	397	1	393	7.0e-73	268	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
644852024	353	38.46	1	347	4	346	3.0e-72	265	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
644852025	116	35.34	3	116	1	113	8.0e-25	105	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
644852026	127	39.37	1	127	1	123	3.0e-24	103	COG5633	Uncharacterized conserved protein YcfL	123
644852027	197	39.5	1	197	4	200	5.0e-38	150	COG3417	Outer membrane lipoprotein LpoB, binds and activates PBP1b	200
644852028	290	24.15	22	280	5	261	8.0e-24	104	COG0510	Thiamine kinase and related kinases	269
644852029	365	45.15	26	319	6	296	2.0e-78	286	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
644852030	180	49.21	1	180	1	189	1.0e-61	229	COG3150	Predicted esterase YcpF, UPF0227 family	191
644852031	435	42.38	7	424	4	405	5.0e-120	424	COG1252	NADH dehydrogenase, FAD-containing subunit	405
644852032	179	83.8	1	179	1	179	3.0e-71	261	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
644852033	357	28.49	7	341	3	333	2.0e-51	196	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644852034	432	22.45	14	432	20	442	5.0e-28	119	COG2271	Sugar phosphate permease	448
644852035	791	33.51	24	787	27	772	0.0e+00	620	COG1501	Alpha-glucosidase, glycosyl hydrolase family GH31	772
644852036	271	36.76	10	256	9	260	1.0e-42	167	COG2162	Arylamine N-acetyltransferase	275
644852037	449	21.84	1	449	6	418	4.0e-61	229	COG0443	Molecular chaperone DnaK (HSP70)	579
644852038	501	38.25	253	501	8	252	3.0e-64	239	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644852039	1150	55.26	12	1149	6	1139	0.0e+00	1524	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
644852040	401	42.58	1	401	1	408	1.0e-104	373	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
644852041	235	48.88	6	227	1	223	5.0e-77	280	COG1136	ABC-type lipoprotein export system, ATPase component	226
644852042	415	41.83	3	415	2	408	3.0e-108	385	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
644852043	310	38.59	1	301	7	306	2.0e-53	203	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
644852044	276	46.15	27	264	1	242	1.0e-71	263	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
644852046	333	68.24	13	330	6	323	3.0e-97	348	COG4139	ABC-type cobalamin transport system, permease component	326
644852047	183	46.99	1	183	1	162	1.0e-61	229	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
644852048	236	50.22	8	232	25	245	1.0e-69	256	COG4138	ABC-type cobalamin transport system, ATPase component	248
644852050	243	24.26	12	236	18	249	4.0e-14	71.9	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644852051	483	48.75	7	483	10	488	0.0e+00	605	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
644852052	563	44.75	1	563	1	561	0.0e+00	534	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
644852053	182	53.3	1	182	1	182	1.0e-64	239	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
644852054	212	35.65	1	209	12	227	2.0e-34	138	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644852056	396	62.12	1	396	1	396	0.0e+00	619	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
644852057	376	42.41	2	376	1	354	1.0e-56	213	COG3203	Outer membrane protein (porin)	354
644852058	379	46.13	2	379	1	354	6.0e-60	224	COG3203	Outer membrane protein (porin)	354
644852059	466	46.48	1	466	2	435	0.0e+00	544	COG0017	Aspartyl/asparaginyl-tRNA synthetase	435
644852060	401	38.73	1	399	3	381	5.0e-96	344	COG1488	Nicotinic acid phosphoribosyltransferase	405
644852061	871	43	1	864	5	859	0.0e+00	745	COG0308	Aminopeptidase N	859
644852064	267	48.78	14	251	1	246	3.0e-73	268	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
644852065	263	49.8	1	255	2	256	7.0e-62	230	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
644852066	382	40.34	8	353	1	332	6.0e-57	215	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
644852067	319	31.8	1	318	1	326	3.0e-46	179	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
644852068	184	39.78	1	178	1	181	6.0e-29	120	COG0431	NAD(P)H-dependent FMN reductase	184
644852069	335	44.3	45	335	3	288	9.0e-91	327	COG0167	Dihydroorotate dehydrogenase	310
644852071	367	57.46	1	267	1	266	3.0e-89	322	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
644852072	707	51.17	1	384	2	381	0.0e+00	464	COG0116	23S rRNA G2445 N2-methylase RlmL	381
644852073	649	44.8	1	531	1	528	0.0e+00	541	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644852074	422	48.26	10	410	17	409	2.0e-125	442	COG2995	Uncharacterized paraquat-inducible protein A	418
644852075	548	44.18	1	547	4	552	0.0e+00	611	COG3008	Paraquat-inducible protein B	553
644852076	186	45.26	1	184	1	188	2.0e-37	148	COG3009	Uncharacterized lipoprotein YmbA	190
644852077	55	76.36	1	55	1	55	6.0e-16	75.8	COG3130	Ribosome modulation factor	55
644852078	350	61.03	1	348	2	350	0.0e+00	536	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
644852080	273	50.36	1	273	2	273	2.0e-87	315	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
644852081	792	49.74	8	790	2	736	0.0e+00	769	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
644852082	370	25.63	1	353	2	347	2.0e-32	133	COG0628	Predicted PurR-regulated permease PerM	355
644852083	1019	32.76	31	543	11	459	1.0e-79	292	COG0277	FAD/FMN-containing dehydrogenase	459
644852084	140	29.93	1	136	1	137	1.0e-26	112	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
644852086	124	36.7	17	124	2	110	3.0e-33	133	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
644852087	499	41.52	42	497	1	412	4.0e-121	428	COG0719	Fe-S cluster assembly scaffold protein SufB	412
644852088	248	57.83	1	248	3	247	2.0e-101	362	COG0396	Fe-S cluster assembly ATPase SufC	251
644852089	430	27.88	31	421	22	410	1.0e-77	283	COG0719	Fe-S cluster assembly scaffold protein SufB	412
644852090	417	52.1	13	414	3	405	0.0e+00	480	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
644852091	148	48.12	14	145	8	140	5.0e-40	156	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
644852092	333	37.73	22	238	21	232	1.0e-33	137	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
644852093	78	69.23	1	78	1	78	5.0e-16	75.9	COG4238	Outer membrane murein-binding lipoprotein Lpp	78
644852094	470	55.79	1	470	4	477	0.0e+00	586	COG0469	Pyruvate kinase	477
644852096	636	29.74	94	471	3	392	1.0e-64	241	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
644852097	465	48.07	3	462	2	456	0.0e+00	571	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
644852098	532	31.97	102	532	13	429	4.0e-87	316	COG4580	Maltoporin (phage lambda and maltose receptor)	429
644852099	394	26.73	80	394	2	297	7.0e-57	214	COG2382	Enterochelin esterase or related enzyme	299
644852101	151	20.91	28	136	21	130	8.0e-07	46.5	COG3631	Ketosteroid isomerase-related protein	133
644852102	280	28.06	10	242	4	252	7.0e-14	71.5	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
644852103	307	35.4	189	301	14	126	4.0e-22	98.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644852106	457	34.8	2	455	10	455	8.0e-74	271	COG0534	Na+-driven multidrug efflux pump	455
644852107	217	46.92	1	211	1	204	1.0e-71	263	COG0307	Riboflavin synthase alpha chain	204
644852108	383	50.35	97	371	1	282	8.0e-95	340	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
644852109	341	45.67	2	335	1	333	8.0e-97	347	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644852111	324	39.16	175	315	56	197	1.0e-30	127	COG0791	Cell wall-associated hydrolase, NlpC family	197
644852112	116	65.71	2	105	1	105	2.0e-45	173	COG0278	Glutaredoxin-related protein	105
644852113	226	34.78	8	210	1	229	2.0e-27	115	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
644852114	135	26.24	1	125	1	138	2.0e-13	68.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644852115	145	30.09	14	126	5	116	1.0e-10	59.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
644852116	155	67.33	5	154	6	154	5.0e-37	147	COG3133	Outer membrane lipoprotein SlyB	154
644852117	370	62.33	1	367	2	370	1.0e-129	456	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
644852118	102	40.82	8	102	15	111	2.0e-20	90.5	COG3895	Membrane-bound inhibitor of C-type lysozyme	112
644852119	232	58.29	23	232	4	214	6.0e-87	313	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
644852120	424	50.47	1	423	1	401	0.0e+00	488	COG0162	Tyrosyl-tRNA synthetase	401
644852121	286	52.63	2	286	1	280	1.0e-96	346	COG2240	Pyridoxal/pyridoxine/pyridoxamine kinase	281
644852122	204	31.88	1	198	1	205	4.0e-29	121	COG0625	Glutathione S-transferase	211
644852123	897	64	8	891	3	860	0.0e+00	1224	COG1048	Aconitase A	861
644852124	539	35.47	1	538	2	562	6.0e-115	408	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
644852125	197	68.04	1	194	1	193	3.0e-76	277	COG0807	GTP cyclohydrolase II	193
644852126	257	21.96	36	233	1	214	1.0e-05	43.7	COG0671	Membrane-associated phospholipid phosphatase	232
644852127	102	75.58	1	86	1	86	1.0e-29	121	COG3771	Uncharacterized membrane protein YciS, DUF1049 family	97
644852128	389	66.07	1	389	1	389	0.0e+00	549	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
644852129	244	48.25	17	244	14	237	1.0e-69	256	COG0284	Orotidine-5'-phosphate decarboxylase	240
644852130	108	54.81	8	108	1	103	4.0e-24	102	COG0023	Translation initiation factor 1 (eIF-1/SUI1)	104
644852132	231	38.96	1	231	4	218	1.0e-58	219	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
644852134	688	43.77	32	685	1	575	0.0e+00	591	COG1966	Carbon starvation protein CstA	575
644852135	305	44.16	1	305	1	298	1.0e-101	363	COG4989	Predicted oxidoreductase	298
644852136	643	75.19	1	643	1	645	0.0e+00	1084	COG4776	Exoribonuclease II	645
644852137	157	28.76	2	154	1	134	1.0e-15	75.9	COG5346	Uncharacterized membrane protein	136
644852139	769	22.4	9	761	9	765	3.0e-102	366	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
644852140	263	60.38	1	260	1	259	1.0e-109	389	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
644852141	271	78.65	2	268	1	267	1.0e-119	422	COG4167	ABC-type antimicrobial peptide transport system, ATPase component	267
644852142	330	82.37	1	329	1	329	0.0e+00	598	COG4170	ABC-type antimicrobial peptide transport system, ATPase component	330
644852143	296	70.27	1	296	1	296	2.0e-111	395	COG4171	ABC-type antimicrobial peptide transport system, permease component	296
644852144	321	74.14	1	321	1	321	6.0e-127	447	COG4168	ABC-type antimicrobial peptide transport system, permease component	321
644852145	582	26.69	14	555	1	560	3.0e-79	289	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
644852146	330	47.27	1	326	73	398	9.0e-88	317	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain	403
644852147	221	44.2	1	221	1	224	6.0e-26	111	COG1842	Phage shock protein A	225
644852149	119	42.65	5	71	1	68	5.0e-16	76.4	COG1983	Phage shock protein PspC (stress-responsive transcriptional regulator)	70
644852150	471	66.52	7	471	2	467	0.0e+00	690	COG3106	Predicted ATPase, YcjX-like family	467
644852151	359	56.73	4	343	1	341	2.0e-106	378	COG3768	Uncharacterized membrane protein YcjF, UPF0283 family	350
644852152	472	21.08	80	460	43	386	2.0e-08	54.4	COG2814	Predicted arabinose efflux permease, MFS family	394
644852153	520	18.87	39	509	12	403	2.0e-26	114	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644852154	536	66.28	16	530	1	511	0.0e+00	713	COG3283	Transcriptional regulator of aromatic amino acids metabolism	511
644852157	182	30.51	1	175	2	178	9.0e-22	96.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644852158	777	26.92	15	750	5	744	4.0e-73	270	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
644852161	167	63.69	3	159	2	158	3.0e-64	237	COG2077	Peroxiredoxin	158
644852163	560	39.64	23	559	4	562	7.0e-123	434	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
644852165	327	23.05	12	327	2	322	5.0e-57	215	COG0598	Mg2+ and Co2+ transporter CorA	322
644852166	313	34.43	17	283	1	266	1.0e-54	207	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
644852169	654	35.94	226	609	4	408	1.0e-50	195	COG0840	Methyl-accepting chemotaxis protein	408
644852170	92	33.33	6	92	5	85	3.0e-07	47	COG3042	Putative hemolysin	85
644852171	330	47.18	1	330	1	323	1.0e-97	349	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
644852172	517	28.5	160	513	30	406	3.0e-44	173	COG0840	Methyl-accepting chemotaxis protein	408
644852175	201	53.47	1	199	1	202	2.0e-69	255	COG1182	FMN-dependent NADH-azoreductase	202
644852176	1295	40.8	18	956	1	845	0.0e+00	832	COG1643	HrpA-like RNA helicase	845
644852177	516	35.25	3	514	2	519	6.0e-90	325	COG1620	L-lactate permease	522
644852178	272	27.68	1	269	1	251	2.0e-45	176	COG3591	V8-like Glu-specific endopeptidase	251
644852181	451	30.7	108	428	11	334	2.0e-39	156	COG0642	Signal transduction histidine kinase	336
644852182	248	40.33	2	242	1	229	1.0e-51	196	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644852184	571	38.96	24	561	16	546	2.0e-103	370	COG0659	Sulfate permease or related transporter, MFS superfamily	554
644852185	366	40.38	4	366	1	366	2.0e-70	259	COG0387	Ca2+/H+ antiporter	368
644852186	224	48.92	34	218	1	184	3.0e-49	188	COG3703	Cation transport regulator ChaC	190
644852187	346	41.23	22	346	9	314	1.0e-68	253	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644852188	286	49.3	1	282	2	285	6.0e-69	254	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644852189	282	42.34	8	276	1	271	1.0e-70	260	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
644852190	227	42.99	5	225	2	221	4.0e-61	228	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
644852191	531	23.27	5	522	21	553	3.0e-50	193	COG0747	ABC-type transport system, periplasmic component	556
644852194	515	31.28	151	515	21	407	1.0e-48	187	COG0840	Methyl-accepting chemotaxis protein	408
644852196	562	33.09	138	517	4	408	5.0e-50	192	COG0840	Methyl-accepting chemotaxis protein	408
644852197	604	37.14	427	599	1	173	3.0e-36	147	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644852199	446	31.97	20	430	11	408	4.0e-79	288	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
644852201	391	30.73	13	380	5	349	8.0e-56	211	COG3500	Phage protein D	350
644852202	165	48.95	2	144	1	141	3.0e-40	157	COG3499	Phage protein U	147
644852206	172	50	1	172	1	169	3.0e-44	171	COG3498	Phage tail tube protein FII	169
644852207	389	53.94	1	387	2	394	1.0e-125	443	COG3497	Phage tail sheath protein FI	394
644852210	184	44.06	1	184	2	203	2.0e-33	135	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
644852212	188	38.55	1	175	7	184	1.0e-36	146	COG2840	DNA-nicking endonuclease, Smr domain	184
644852213	448	21.11	44	431	49	431	1.0e-16	81.8	COG2271	Sugar phosphate permease	448
644852214	451	23.22	49	393	64	380	6.0e-14	72.7	COG4222	Uncharacterized conserved protein	391
644852216	203	49.51	1	201	1	204	1.0e-58	219	COG4385	Bacteriophage P2-related tail formation protein	206
644852217	302	61.26	1	302	5	306	4.0e-99	354	COG3948	Phage-related baseplate assembly protein	306
644852218	116	50	3	100	2	99	1.0e-28	118	COG3628	Phage baseplate assembly protein W	116
644852219	217	39.2	18	216	2	183	6.0e-41	160	COG4540	Phage P2 baseplate assembly protein gpV	184
644852221	67	48.53	1	67	3	70	2.0e-18	83.9	COG5004	P2-like prophage tail protein X	70
644852230	667	39.53	253	609	27	408	6.0e-55	209	COG0840	Methyl-accepting chemotaxis protein	408
644852232	482	38.97	27	312	71	354	3.0e-75	276	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
644852233	876	45.98	1	568	1	553	0.0e+00	578	COG3008	Paraquat-inducible protein B	553
644852234	454	52.27	59	452	12	407	5.0e-124	438	COG2995	Uncharacterized paraquat-inducible protein A	418
644852235	168	61.69	1	154	10	163	3.0e-55	207	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
644852236	243	62.96	1	243	1	208	2.0e-62	232	COG3109	sRNA-binding protein	208
644852237	673	35.53	122	589	1	406	2.0e-95	343	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
644852239	422	21.98	1	367	9	340	1.0e-17	84.8	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
644852240	215	46.38	8	214	3	208	3.0e-52	198	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644852241	603	42.33	7	594	1	573	0.0e+00	508	COG3850	Signal transduction histidine kinase, nitrate/nitrite-specific	574
644852242	463	42.66	25	460	2	404	1.0e-93	337	COG2223	Nitrate/nitrite transporter NarK	417
644852243	335	23.38	75	267	12	203	9.0e-15	74.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644852244	296	31	3	296	2	295	1.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
644852245	1257	77.1	1	1235	1	1227	0.0e+00	2153	COG5013	Nitrate reductase alpha subunit	1227
644852246	520	78.82	1	508	1	510	0.0e+00	943	COG1140	Nitrate reductase beta subunit	513
644852247	239	47.49	1	179	4	178	9.0e-39	153	COG2180	Nitrate reductase assembly protein NarJ, required for insertion of molybdenum cofactor	179
644852248	225	58.67	3	225	1	225	7.0e-69	253	COG2181	Nitrate reductase gamma subunit	228
644852249	382	50	5	382	4	377	1.0e-122	433	COG1454	Alcohol dehydrogenase, class IV	377
644852251	125	36.67	5	123	7	126	8.0e-24	102	COG3654	Prophage maintenance system killer protein	132
644852253	343	31.61	1	339	1	330	5.0e-70	258	COG0620	Methionine synthase II (cobalamin-independent)	330
644852255	76	29.69	1	64	1	64	6.0e-08	49.2	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
644852256	364	45.15	1	360	2	352	1.0e-113	403	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644852257	495	39.29	17	488	1	454	2.0e-109	390	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644852258	421	50.93	1	420	16	444	0.0e+00	493	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
644852259	486	48.53	11	484	1	471	0.0e+00	520	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644852260	343	26.94	5	340	16	363	7.0e-52	197	COG0687	Spermidine/putrescine-binding periplasmic protein	363
644852261	423	42.96	147	423	12	287	3.0e-64	239	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
644852262	278	44.14	21	276	12	267	4.0e-59	221	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
644852263	297	32	3	295	2	297	6.0e-30	124	COG0583	DNA-binding transcriptional regulator, LysR family	297
644852264	200	32.51	5	198	3	204	6.0e-27	114	COG0625	Glutathione S-transferase	211
644852266	259	34.78	6	257	1	253	6.0e-51	194	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
644852267	263	34.1	6	262	3	260	2.0e-57	216	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
644852268	392	19.58	32	383	21	401	7.0e-08	52.1	COG0738	Fucose permease	422
644852269	270	26.87	1	266	2	264	4.0e-32	132	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
644852270	661	41.55	261	608	36	408	2.0e-55	210	COG0840	Methyl-accepting chemotaxis protein	408
644852271	409	69.6	1	398	1	397	0.0e+00	564	COG1133	ABC-type long-chain fatty acid transport system, fused permease and ATPase components	405
644852273	361	33.05	1	348	6	352	4.0e-67	248	COG1377	Flagellar biosynthesis protein FlhB	363
644852274	267	30.38	5	241	1	235	5.0e-25	108	COG4791	Type III secretory pathway, component EscT	259
644852275	86	49.35	9	85	12	88	2.0e-11	60.6	COG4794	Type III secretory pathway, component EscS	89
644852276	217	47.39	7	217	3	213	5.0e-55	207	COG4790	Type III secretory pathway, component EscR	214
644852277	387	20.8	253	373	12	135	7.0e-08	51.9	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
644852280	459	50.79	10	453	1	438	0.0e+00	522	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
644852282	700	42.45	7	691	1	688	0.0e+00	628	COG4789	Type III secretory pathway, component EscV	689
644852284	184	28.65	13	183	7	176	3.0e-22	98.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644852286	213	39.71	5	212	1	209	3.0e-45	175	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644852290	261	40.25	8	242	4	232	7.0e-49	187	COG4669	Type III secretory pathway, lipoprotein EscJ	246
644852293	435	46.78	64	356	41	333	1.0e-79	290	COG2951	Membrane-bound lytic murein transglycosylase B	343
644852298	691	25.59	32	545	26	555	4.0e-62	233	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
644852302	131	43.9	7	128	17	138	3.0e-28	117	COG4101	Uncharacterized protein, RmlC-like cupin domain	142
644852303	558	32.42	20	558	13	554	6.0e-103	368	COG2831	Hemolysin activation/secretion protein	554
644852309	369	38.06	44	331	19	298	4.0e-62	232	COG4974	Site-specific recombinase XerD	300
644852315	369	38.06	44	331	19	298	4.0e-62	232	COG4974	Site-specific recombinase XerD	300
644852319	87	35.8	3	79	5	85	9.0e-07	45.1	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
644852320	103	38.54	1	95	2	97	4.0e-14	69.7	COG3668	Plasmid stabilization system protein ParE	98
644852321	79	20.27	7	79	2	75	1.0e-05	41.3	COG1918	Fe2+ transport system protein FeoA	75
644852322	75	43.84	1	73	1	72	4.0e-11	59.4	COG1918	Fe2+ transport system protein FeoA	75
644852323	774	41.8	4	733	3	650	0.0e+00	649	COG0370	Fe2+ transport system protein B	653
644852326	423	46.51	1	408	3	414	7.0e-129	453	COG2195	Di- or tripeptidase	414
644852327	373	58.93	1	373	9	383	0.0e+00	465	COG2850	Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain	383
644852328	483	24.55	156	482	7	336	4.0e-35	143	COG0642	Signal transduction histidine kinase	336
644852329	222	41.41	1	221	1	226	1.0e-52	199	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644852330	455	35.09	12	455	1	435	1.0e-119	423	COG0015	Adenylosuccinate lyase	438
644852331	210	66.02	2	207	1	206	4.0e-72	264	COG2915	Regulator of phage lambda lysogenization HflD, binds to CII and stimulates its degradation	207
644852332	372	61.81	6	367	1	355	0.0e+00	511	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
644852333	152	26.09	4	116	9	123	2.0e-09	55.4	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
644852335	417	67.07	10	417	2	406	0.0e+00	618	COG0538	Isocitrate dehydrogenase	407
644852337	294	32.31	2	289	22	295	2.0e-44	173	COG0501	Zn-dependent protease with chaperone function	302
644852338	388	15.9	1	387	58	425	4.0e-35	142	COG0823	Periplasmic component of the Tol biopolymer transport system	425
644852339	263	43.09	14	258	1	246	2.0e-69	255	COG1414	DNA-binding transcriptional regulator, IclR family	246
644852341	642	55.01	34	641	1	589	0.0e+00	811	COG0441	Threonyl-tRNA synthetase	589
644852342	180	66.67	4	180	1	176	7.0e-65	239	COG0290	Translation initiation factor IF-3	176
644852343	65	67.69	1	65	1	65	3.0e-11	60.2	COG0291	Ribosomal protein L35	65
644852344	118	82.2	1	118	1	118	2.0e-40	157	COG0292	Ribosomal protein L20	118
644852345	327	58.86	1	325	3	335	0.0e+00	465	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
644852346	795	48.63	143	794	1	650	0.0e+00	726	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
644852347	99	50.54	2	94	1	93	2.0e-28	116	COG0776	Bacterial nucleoid DNA-binding protein	94
644852350	274	44.57	17	274	3	262	1.0e-76	279	COG0171	NH3-dependent NAD+ synthetase	268
644852352	463	73.96	1	457	2	457	0.0e+00	603	COG1823	L-cystine uptake protein TcyP, sodium:dicarboxylate symporter family	458
644852353	192	35.76	1	160	1	158	5.0e-20	90.9	COG1988	Membrane-bound metal-dependent hydrolase YbcI, DUF457 family	190
644852354	308	22.18	43	297	52	307	1.0e-20	94.2	COG0657	Acetyl esterase/lipase	312
644852356	430	26.56	1	426	5	432	1.0e-44	174	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
644852357	375	47.01	1	368	1	338	2.0e-116	412	COG3839	ABC-type sugar transport system, ATPase component	338
644852358	300	36.04	19	299	1	281	3.0e-61	228	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
644852359	296	43.86	4	284	8	290	4.0e-54	205	COG1175	ABC-type sugar transport system, permease component	295
644852361	253	37.25	6	251	1	251	2.0e-47	182	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644852362	278	70.14	1	278	1	278	0.0e+00	460	COG3717	5-keto 4-deoxyuronate isomerase	278
644852363	110	28.71	8	105	19	119	6.0e-10	56	COG1917	Cupin domain protein related to quercetin dioxygenase	131
644852365	285	61.27	1	284	1	284	6.0e-112	396	COG3001	Fructosamine-3-kinase	286
644852367	69	70.15	3	69	1	67	2.0e-24	104	COG1278	Cold shock protein, CspA family	67
644852369	190	53.19	1	186	1	188	9.0e-45	173	COG1971	Putative Mn2+ efflux pump MntP	190
644852370	152	57.89	1	152	1	152	2.0e-41	161	COG4811	Uncharacterized membrane protein YobD, UPF0266 family	152
644852371	278	58.67	6	276	5	269	4.0e-108	384	COG3716	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID	269
644852372	265	55.85	2	265	1	264	4.0e-68	251	COG3715	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC	265
644852373	318	64.78	157	315	1	159	4.0e-58	218	COG3444	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB	159
644852374	517	53.85	1	243	8	254	4.0e-73	269	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
644852375	453	53.76	171	449	3	262	2.0e-91	329	COG1760	L-serine deaminase	262
644852376	217	18.84	34	162	1	134	2.0e-07	49.2	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
644852377	456	41.28	27	455	24	459	0.0e+00	470	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
644852378	62	76.27	1	58	1	59	6.0e-11	59.3	COG3140	Uncharacterized conserved protein YoaH, UPF0181 family	60
644852379	115	33.61	1	115	8	129	6.0e-24	102	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
644852380	649	43.87	20	648	1	650	0.0e+00	534	COG1199	Rad3-related DNA helicase	654
644852381	233	43.42	4	228	2	219	1.0e-54	206	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
644852382	209	46.52	19	204	4	189	4.0e-52	197	COG3065	Starvation-inducible outer membrane lipoprotein	191
644852383	567	40.29	24	563	1	524	0.0e+00	461	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644852384	373	50.82	6	370	1	359	6.0e-108	384	COG0349	Ribonuclease D	361
644852385	97	60.47	1	86	1	85	4.0e-26	109	COG0851	Septum formation topological specificity factor MinE	88
644852386	270	75.93	1	270	1	269	4.0e-125	440	COG2894	Septum formation inhibitor-activating ATPase MinD	272
644852387	232	48.46	6	231	1	217	3.0e-60	225	COG0850	Septum formation inhibitor MinC	219
644852388	90	62.22	1	90	11	100	8.0e-30	121	COG3100	Uncharacterized conserved protein YcgL, UPF0745 family	103
644852389	218	44.75	1	209	37	253	1.0e-64	239	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
644852390	148	60.14	1	148	6	153	1.0e-57	215	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
644852391	176	42.44	1	168	1	170	8.0e-30	123	COG1495	Disulfide bond formation protein DsbB	170
644852392	239	28.51	1	233	1	241	6.0e-38	150	COG2186	DNA-binding transcriptional regulator, FadR family	241
644852393	511	73.39	13	508	2	491	0.0e+00	742	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
644852394	416	31.62	1	416	5	382	3.0e-49	189	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644852395	402	50.64	10	400	1	379	2.0e-110	392	COG3328	Transposase (or an inactivated derivative)	379
644852399	87	35.8	3	79	5	85	9.0e-07	45.1	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
644852400	373	24.11	66	308	1	250	1.0e-18	87.5	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
644852405	224	26.4	1	183	2	193	3.0e-17	82.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644852411	1162	38.99	14	1144	6	1068	0.0e+00	839	COG1330	Exonuclease V gamma subunit	1078
644852412	1224	31.66	5	1189	3	1139	0.0e+00	690	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
644852413	681	29.11	6	680	41	689	5.0e-92	332	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
644852414	457	46.46	1	373	28	407	2.0e-114	406	COG0513	Superfamily II DNA and RNA helicase	513
644852415	373	40.69	1	363	3	356	2.0e-83	302	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
644852417	305	29.04	4	301	1	296	4.0e-38	152	COG0583	DNA-binding transcriptional regulator, LysR family	297
644852419	268	36.7	3	185	4	191	6.0e-38	151	COG0300	Short-chain dehydrogenase	265
644852421	478	24.81	2	442	18	548	2.0e-58	220	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
644852423	346	60.18	6	337	10	342	2.0e-118	419	COG3720	Putative heme degradation protein	349
644852424	227	44.3	1	223	1	227	5.0e-54	204	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644852425	481	26.54	165	471	18	319	2.0e-33	137	COG0642	Signal transduction histidine kinase	336
644852427	185	33.33	7	177	4	155	9.0e-11	60.2	COG4960	Flp pilus assembly protein, protease CpaA	168
644852428	308	27.74	1	308	1	269	3.0e-24	105	COG3745	Flp pilus assembly protein CpaB	276
644852429	474	35.51	19	456	4	415	1.0e-71	264	COG4964	Flp pilus assembly protein, secretin CpaC	455
644852430	223	26.76	9	211	6	214	4.0e-11	61.6	COG5461	Type IV pilus biogenesis protein CpaD/CtpE	224
644852431	401	26.2	135	401	92	359	6.0e-22	98.9	COG4963	Flp pilus assembly protein, ATPase CpaE	366
644852432	458	56.4	87	430	17	355	5.0e-110	391	COG4962	Pilus assembly protein, ATPase of CpaF family	355
644852433	325	27.27	5	323	1	307	1.0e-34	140	COG4965	Flp pilus assembly protein TadB	309
644852435	283	26.61	14	258	12	247	8.0e-14	71.2	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
644852440	605	19.11	39	503	1	457	3.0e-16	80.6	COG1538	Outer membrane protein TolC	457
644852445	363	43.47	1	362	1	362	5.0e-96	344	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
644852446	260	40.46	1	258	4	265	8.0e-65	240	COG0300	Short-chain dehydrogenase	265
644852447	270	32.12	1	264	3	258	1.0e-41	163	COG0300	Short-chain dehydrogenase	265
644852449	334	37.83	1	333	1	326	1.0e-60	227	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
644852450	363	61.56	1	363	1	372	0.0e+00	527	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
644852451	195	55.5	3	193	1	190	8.0e-74	269	COG0193	Peptidyl-tRNA hydrolase	190
644852453	300	25.59	6	298	2	291	6.0e-32	131	COG0583	DNA-binding transcriptional regulator, LysR family	297
644852454	261	32.21	52	257	12	188	3.0e-26	112	COG0693	Putative intracellular protease/amidase	188
644852455	315	60.44	1	314	2	314	3.0e-123	435	COG0462	Phosphoribosylpyrophosphate synthetase	314
644852456	290	49.13	7	280	5	287	5.0e-90	324	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
644852457	206	50.72	1	206	1	206	1.0e-52	199	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
644852458	418	50.48	1	418	1	412	0.0e+00	475	COG0373	Glutamyl-tRNA reductase	414
644852459	360	68.32	1	359	1	363	0.0e+00	564	COG0216	Protein chain release factor A	363
644852460	283	45.55	1	279	1	280	7.0e-78	284	COG2890	Methylase of polypeptide chain release factors	280
644852462	269	53.16	1	269	2	269	2.0e-82	299	COG2912	Regulator of sirC expression, contains transglutaminase-like and TPR domains	269
644852463	284	65.48	2	282	1	279	0.0e+00	469	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
644852465	509	63.19	2	365	1	356	0.0e+00	465	COG3288	NAD/NADP transhydrogenase alpha subunit	356
644852466	457	59.53	2	457	7	463	0.0e+00	633	COG1282	NAD/NADP transhydrogenase beta subunit	463
644852467	323	24.05	155	303	7	154	1.0e-11	64.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
644852468	250	36.41	31	235	7	212	5.0e-39	154	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
644852469	179	43.71	3	167	1	167	1.0e-45	176	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
644852472	653	38.93	256	605	34	408	5.0e-51	196	COG0840	Methyl-accepting chemotaxis protein	408
644852473	425	34.41	3	422	11	441	9.0e-65	241	COG3037	Ascorbate-specific PTS system EIIC-type component UlaA	481
644852474	168	58.49	7	164	5	163	3.0e-63	234	COG3479	Phenolic acid decarboxylase	175
644852475	298	26.09	7	278	2	277	2.0e-22	99.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
644852476	374	25.73	76	368	1	306	4.0e-39	156	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
644852477	359	45.1	1	356	3	352	4.0e-100	358	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644852478	284	26.24	1	281	10	284	4.0e-27	115	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
644852479	277	31.2	7	272	6	266	3.0e-37	148	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
644852480	377	29.35	35	326	21	323	2.0e-45	176	COG4134	ABC-type uncharacterized transport system YnjBCD, periplasmic component	384
644852481	252	32.81	13	251	2	250	2.0e-31	129	COG0584	Glycerophosphoryl diester phosphodiesterase	257
644852482	254	38.6	4	224	1	228	3.0e-47	182	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
644852484	612	20.75	13	603	7	536	3.0e-41	163	COG2303	Choline dehydrogenase or related flavoprotein	542
644852486	844	39.42	9	843	1	820	0.0e+00	741	COG4458	Uncharacterized protein	821
644852487	996	58.64	1	996	1	1014	0.0e+00	1369	COG4457	Uncharacterized protein	1014
644852490	285	37.18	1	269	2	275	4.0e-29	121	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
644852492	575	56.46	10	571	13	577	0.0e+00	686	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
644852493	448	19.19	27	368	16	277	1.0e-08	54.6	COG1566	Multidrug resistance efflux pump	352
644852494	466	25.06	28	444	45	455	2.0e-34	140	COG1538	Outer membrane protein TolC	457
644852498	207	22.56	5	199	10	197	1.0e-11	63.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644852500	231	58.96	21	231	22	231	1.0e-74	272	COG4305	Peptidoglycan-binding domain, expansin	232
644852501	322	30.48	1	310	2	316	4.0e-40	158	COG1275	Tellurite resistance protein TehA and related permeases	329
644852502	334	24.19	1	334	5	331	3.0e-31	129	COG3274	Surface polysaccharide O-acyltransferase, integral membrane enzyme	332
644852503	114	31.9	1	114	1	104	1.0e-15	75.3	COG2315	Predicted DNA-binding protein with ?double-wing? structural motif, MmcQ/YjbR family	118
644852504	297	31.97	5	294	2	288	9.0e-35	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
644852505	134	25.2	1	126	1	126	8.0e-10	56.1	COG4319	Ketosteroid isomerase homolog	137
644852510	160	44.23	1	103	1	104	8.0e-22	96.6	COG1733	DNA-binding transcriptional regulator, HxlR family	120
644852511	329	27.13	4	250	2	224	4.0e-19	89.2	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
644852512	273	39.33	9	266	9	273	6.0e-46	177	COG3769	Predicted mannosyl-3-phosphoglycerate phosphatase, HAD superfamily	274
644852514	249	55	2	240	8	246	5.0e-86	310	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
644852516	223	50.45	1	219	1	221	4.0e-61	227	COG0132	Dethiobiotin synthetase	223
644852517	405	29.36	80	405	1	314	3.0e-50	192	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
644852518	304	34.8	3	295	1	288	2.0e-38	152	COG0583	DNA-binding transcriptional regulator, LysR family	297
644852519	425	24.4	43	414	10	381	7.0e-23	102	COG2814	Predicted arabinose efflux permease, MFS family	394
644852521	465	69.91	2	463	1	462	0.0e+00	782	COG0114	Fumarate hydratase class II	462
644852522	394	34.96	1	389	3	310	4.0e-85	308	COG1482	Mannose-6-phosphate isomerase, class I	312
644852523	517	31.3	4	490	1	474	4.0e-75	275	COG5339	Uncharacterized conserved protein YdgA, DUF945 family	479
644852524	154	38.16	1	152	3	153	6.0e-32	130	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644852526	337	38.87	1	334	6	339	7.0e-87	314	COG1816	Adenosine deaminase	345
644852527	152	50.98	4	151	2	154	2.0e-47	181	COG4875	Uncharacterized protein	156
644852528	333	39.27	1	331	1	318	1.0e-67	250	COG0385	Predicted Na+-dependent transporter	319
644852529	349	30.62	4	348	3	342	5.0e-52	198	COG0673	Predicted dehydrogenase	342
644852530	316	29.27	165	287	2	124	6.0e-22	98.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644852531	328	40.45	16	326	2	314	7.0e-59	221	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
644852532	507	50.8	1	496	2	498	0.0e+00	636	COG1129	ABC-type sugar transport system, ATPase component	500
644852533	327	24	5	325	13	320	1.0e-31	131	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
644852534	561	41.71	5	561	3	537	0.0e+00	599	COG1069	Ribulose kinase	544
644852535	503	66.67	1	498	1	495	0.0e+00	747	COG2160	L-arabinose isomerase	497
644852538	193	80.31	1	193	1	193	4.0e-68	250	COG4657	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfA subunit	193
644852539	196	64.4	1	190	1	191	1.0e-67	249	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
644852540	673	59.43	11	536	1	529	0.0e+00	649	COG4656	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfC subunit	529
644852541	350	59.31	2	350	1	336	2.0e-111	396	COG4658	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfD subunit	338
644852542	210	65.31	3	198	1	195	4.0e-75	274	COG4659	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit	195
644852543	230	76.89	1	212	1	212	7.0e-86	310	COG4660	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfE subunit	212
644852544	211	55.24	1	210	1	210	8.0e-85	306	COG0177	Endonuclease III	211
644852545	324	26.67	1	298	1	294	2.0e-37	150	COG0583	DNA-binding transcriptional regulator, LysR family	297
644852546	867	48.75	3	595	1	569	0.0e+00	686	COG0550	DNA topoisomerase IA	570
644852550	348	32.47	45	341	5	310	2.0e-58	219	COG0616	Periplasmic serine protease, ClpP class	317
644852551	253	29.37	10	247	3	250	4.0e-40	158	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644852552	196	58.59	1	196	1	198	6.0e-76	276	COG2109	ATP:corrinoid adenosyltransferase	198
644852553	301	47.81	1	246	1	247	4.0e-71	261	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
644852554	206	44.39	2	205	1	204	2.0e-60	225	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
644852555	290	51.56	13	268	3	254	1.0e-67	249	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
644852556	520	42.77	17	518	9	462	0.0e+00	463	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
644852557	192	49.48	1	190	1	191	1.0e-67	249	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
644852558	332	51.51	1	330	4	334	7.0e-110	390	COG0547	Anthranilate phosphoribosyltransferase	338
644852559	461	52.17	6	254	1	253	3.0e-90	326	COG0134	Indole-3-glycerol phosphate synthase	254
644852560	396	68.53	1	394	2	394	0.0e+00	691	COG0133	Tryptophan synthase beta chain	396
644852561	269	46.82	1	267	1	264	3.0e-89	321	COG0159	Tryptophan synthase alpha chain	265
644852564	210	63.13	1	210	1	213	2.0e-66	245	COG3047	Outer membrane protein W	213
644852565	120	29.2	1	111	6	115	3.0e-11	60.4	COG0727	Fe-S-cluster containining protein	132
644852567	186	60.56	1	180	1	180	2.0e-57	215	COG2917	Intracellular septation protein A	180
644852568	140	57.25	1	131	3	130	1.0e-47	182	COG1607	Acyl-CoA hydrolase	157
644852569	249	29.82	10	232	1	228	4.0e-15	75.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
644852570	98	58.16	1	98	1	92	5.0e-25	105	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
644852571	566	29.37	181	533	33	408	5.0e-37	149	COG0840	Methyl-accepting chemotaxis protein	408
644852573	486	37.17	47	486	1	438	1.0e-88	320	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
644852574	107	76.64	1	107	2	108	4.0e-41	159	COG3099	Uncharacterized conserved protein YciU, UPF0263 family	108
644852576	329	58.36	11	323	1	314	1.0e-129	456	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
644852577	302	42.61	20	302	5	287	3.0e-71	261	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644852578	306	44.3	1	306	1	315	3.0e-84	305	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644852579	547	41.46	6	546	2	562	2.0e-130	459	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
644852580	214	44.02	5	213	1	203	3.0e-43	168	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
644852581	900	20.52	1	445	30	472	5.0e-62	233	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644852581	900	47.09	451	862	1	377	1.0e-124	440	COG1454	Alcohol dehydrogenase, class IV	377
644852582	199	49.49	1	197	3	199	2.0e-74	271	COG1435	Thymidine kinase	201
644852583	135	68.22	7	135	1	127	8.0e-31	125	COG2916	DNA-binding protein H-NS	128
644852584	303	58.05	5	300	1	290	9.0e-116	409	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
644852586	304	37	1	288	7	280	3.0e-54	205	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
644852587	155	49.68	1	155	1	151	4.0e-49	187	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
644852588	283	51.75	3	283	2	287	1.0e-109	389	COG0788	Formyltetrahydrofolate hydrolase	287
644852590	206	48.53	1	203	5	208	5.0e-53	200	COG2860	Uncharacterized membrane protein YeiH	209
644852591	268	48.52	1	268	1	261	5.0e-92	331	COG0708	Exonuclease III	261
644852593	641	34.26	1	609	1	557	0.0e+00	533	COG0550	DNA topoisomerase IA	570
644852594	183	28.22	1	183	3	204	1.0e-16	80	COG0778	Nitroreductase	207
644852595	616	36.83	272	582	4	317	2.0e-67	250	COG0616	Periplasmic serine protease, ClpP class	317
644852596	339	36.44	1	333	17	351	1.0e-85	310	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
644852597	213	29.95	1	213	4	204	3.0e-32	131	COG1335	Nicotinamidase-related amidase	205
644852598	91	71.11	1	88	1	90	7.0e-29	118	COG3139	Uncharacterized conserved protein YeaC, DUF1315 family	90
644852599	138	59.5	12	132	11	131	2.0e-52	198	COG0229	Peptide methionine sulfoxide reductase MsrB	140
644852600	331	66.97	2	331	1	332	0.0e+00	479	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
644852601	290	50.17	4	290	2	286	3.0e-91	328	COG0676	D-hexose-6-phosphate mutarotase	287
644852602	283	40.78	1	276	2	268	8.0e-71	260	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
644852603	249	39.68	5	249	12	258	2.0e-53	202	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
644852604	644	70.88	1	644	1	649	0.0e+00	918	COG2766	Predicted Ser/Thr protein kinase	649
644852605	431	71.36	7	431	1	422	0.0e+00	583	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
644852606	267	40.47	1	242	1	256	4.0e-65	241	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
644852608	502	24.52	1	466	7	523	3.0e-50	193	COG0747	ABC-type transport system, periplasmic component	556
644852609	582	31.58	25	316	13	309	4.0e-35	143	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644852610	82	59.26	1	81	1	80	4.0e-09	52.7	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
644852617	106	34.83	17	100	19	106	5.0e-09	52.6	COG1662	Transposase and inactivated derivatives, IS1 family	121
644852621	169	54.27	1	164	1	164	2.0e-57	215	COG1528	Ferritin	167
644852622	291	35.29	5	291	2	287	5.0e-30	125	COG1276	Putative copper export protein	289
644852623	126	36.29	6	126	4	125	9.0e-19	85.8	COG2372	Copper-binding protein CopC (methionine-rich)	127
644852626	683	55	1	677	4	680	0.0e+00	885	COG1770	Protease II	682
644852627	393	71.07	1	392	1	394	0.0e+00	632	COG0027	Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	394
644852628	213	54.11	4	209	2	207	8.0e-63	233	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
644852629	491	55.97	5	489	3	482	0.0e+00	702	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
644852630	289	45.16	1	278	3	281	1.0e-72	266	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
644852631	480	52.39	2	479	1	477	0.0e+00	578	COG0469	Pyruvate kinase	477
644852634	328	38.24	14	318	2	307	2.0e-88	319	COG1560	Lauroyl/myristoyl acyltransferase	308
644852635	470	29.57	128	453	3	274	4.0e-35	142	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
644852636	340	52.92	14	338	10	317	1.0e-111	396	COG4531	ABC-type Zn2+ transport system, periplasmic component/surface adhesin	318
644852637	252	45.49	1	236	1	254	2.0e-74	272	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
644852638	261	46.12	1	258	10	267	6.0e-45	174	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
644852639	336	70.73	4	331	1	328	0.0e+00	545	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
644852640	205	47.34	1	205	1	201	1.0e-63	236	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
644852642	303	54.14	5	294	13	302	2.0e-97	348	COG3376	High-affinity nickel permease	342
644852643	173	61.15	5	160	1	157	3.0e-58	217	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
644852644	247	60.74	1	241	1	241	8.0e-100	356	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
644852645	149	22.63	1	136	6	141	9.0e-11	59.6	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
644852646	596	62.77	1	586	1	585	0.0e+00	931	COG0173	Aspartyl-tRNA synthetase	585
644852647	270	35.13	1	265	3	263	1.0e-47	183	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
644852648	131	65.35	1	127	5	131	1.0e-37	148	COG3788	Uncharacterized membrane protein YecN, MAPEG domain	131
644852652	254	48.57	1	243	1	240	3.0e-76	278	COG3142	Copper homeostasis protein CutC	241
644852653	190	60.69	13	185	13	185	4.0e-65	240	COG3102	Uncharacterized conserved protein YecM, predicted metalloenzyme	185
644852654	576	41.2	1	576	1	577	0.0e+00	613	COG0018	Arginyl-tRNA synthetase	577
644852655	530	35.34	186	508	62	408	5.0e-36	145	COG0840	Methyl-accepting chemotaxis protein	408
644852656	511	53.5	1	510	7	518	1.0e-124	440	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
644852657	307	28.18	1	305	1	330	2.0e-44	172	COG0673	Predicted dehydrogenase	342
644852658	214	68.66	1	213	1	215	5.0e-76	277	COG3132	Uncharacterized conserved protein YceH, UPF0502 family	215
644852659	194	29.35	12	194	4	186	7.0e-26	110	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644852660	398	20.42	60	389	65	390	1.0e-10	61.4	COG2814	Predicted arabinose efflux permease, MFS family	394
644852661	215	58.14	1	215	1	215	3.0e-75	274	COG2999	Glutaredoxin 2	215
644852663	200	41.03	9	188	7	199	4.0e-34	138	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
644852664	245	32.5	2	235	1	237	3.0e-49	189	COG1387	Histidinol phosphatase or related hydrolase of the PHP family	237
644852666	215	24.59	32	209	13	194	3.0e-06	45.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644852667	319	29.01	9	269	3	246	5.0e-17	82.3	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
644852668	307	36.04	190	300	17	127	2.0e-20	93.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644852669	384	38.67	8	364	6	358	8.0e-85	307	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
644852670	233	27.75	1	205	2	227	2.0e-29	123	COG0300	Short-chain dehydrogenase	265
644852673	308	27.76	6	296	5	273	5.0e-30	125	COG0388	Predicted amidohydrolase	274
644852674	311	26.33	9	299	1	293	4.0e-24	105	COG0583	DNA-binding transcriptional regulator, LysR family	297
644852675	251	37.3	1	251	1	252	6.0e-55	207	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
644852677	212	32.07	24	195	45	228	1.0e-31	129	COG3719	Ribonuclease I	249
644852679	370	36.93	7	354	6	335	3.0e-78	285	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
644852680	134	39.66	6	121	3	118	9.0e-27	112	COG1733	DNA-binding transcriptional regulator, HxlR family	120
644852681	551	33.09	3	551	1	449	2.0e-71	263	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
644852682	446	22.67	41	424	3	385	4.0e-32	132	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644852684	1478	82.68	1	1478	1	1478	0.0e+00	2142	COG3096	Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Escherichia coli str. K-12 substr. MG1655	1480
644852685	244	75.93	3	243	1	238	1.0e-101	362	COG3095	Chromosome condensin MukBEF, MukE localization factor	238
644852686	440	86.36	1	440	1	440	0.0e+00	737	COG3006	Chromosome condensin MukBEF complex, kleisin-like MukF subunit	440
644852688	258	30.71	16	253	1	223	5.0e-24	104	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
644852691	250	66.8	1	250	2	245	2.0e-104	372	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
644852692	60	70.18	1	57	1	57	1.0e-17	81.4	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
644852693	337	54.23	1	313	4	319	1.0e-102	366	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
644852694	582	40.49	10	582	1	567	0.0e+00	484	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
644852695	793	34.69	499	779	10	292	8.0e-62	232	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
644852697	112	83.33	5	106	3	104	7.0e-32	128	COG2926	Uncharacterized conserved protein YeeX, DUF496 family	109
644852698	476	70.53	1	475	2	475	0.0e+00	757	COG2925	Exonuclease I	475
644852699	453	25.22	5	437	1	442	1.0e-29	124	COG0531	Amino acid transporter	466
644852701	250	29.18	16	247	6	231	1.0e-36	146	COG5581	c-di-GMP-binding flagellar brake protein YcgR, contains PilZNR and PilZ domains	233
644852702	302	46.32	40	302	15	286	2.0e-57	215	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
644852703	180	37.93	1	174	1	174	1.0e-39	155	COG3697	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase)	182
644852704	509	67.06	1	506	1	513	0.0e+00	776	COG3051	Citrate lyase, alpha subunit	513
644852705	301	45.1	17	300	1	281	3.0e-78	285	COG2301	Citrate lyase beta subunit	283
644852706	96	51.55	1	96	1	97	7.0e-25	105	COG3052	Citrate lyase, gamma subunit	98
644852707	347	51.82	15	343	11	338	3.0e-115	408	COG3053	Citrate lyase synthetase	352
644852708	294	35.29	21	278	1	265	4.0e-60	224	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
644852709	455	40	29	454	14	438	4.0e-97	348	COG3493	Na+/citrate or Na+/malate symporter	438
644852710	531	39.7	2	528	7	531	1.0e-121	430	COG3290	Sensor histidine kinase regulating citrate/malate metabolism	537
644852711	241	39.29	17	240	2	224	2.0e-58	219	COG4565	Response regulator of citrate/malate metabolism	224
644852712	655	38.01	262	607	38	408	1.0e-50	195	COG0840	Methyl-accepting chemotaxis protein	408
644852713	273	23.49	2	266	1	296	6.0e-23	101	COG0451	Nucleoside-diphosphate-sugar epimerase	314
644852714	299	57.24	5	299	1	290	2.0e-104	372	COG0040	ATP phosphoribosyltransferase	290
644852715	436	54.21	11	433	1	425	0.0e+00	564	COG0141	Histidinol dehydrogenase	425
644852716	356	39.72	6	354	1	354	1.0e-87	317	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
644852717	355	63.08	164	355	1	195	7.0e-84	304	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
644852718	196	55.72	1	196	2	202	1.0e-78	285	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
644852719	245	52.03	1	245	3	241	4.0e-79	287	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
644852720	258	54.62	1	258	1	256	3.0e-111	394	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
644852721	204	55.05	1	108	2	109	4.0e-40	157	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
644852723	94	49.46	1	93	2	93	9.0e-29	118	COG0776	Bacterial nucleoid DNA-binding protein	94
644852724	569	60.8	13	562	1	541	0.0e+00	613	COG0539	Ribosomal protein S1	541
644852725	229	60.09	4	225	3	221	4.0e-80	290	COG0283	Cytidylate kinase	222
644852726	429	48.73	3	426	2	425	0.0e+00	495	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
644852727	361	61.81	1	361	3	365	0.0e+00	524	COG1932	Phosphoserine aminotransferase	365
644852728	587	44.89	1	418	4	396	4.0e-115	408	COG1944	Ribosomal protein S12 methylthiotransferase accessory factor YcaO	398
644852729	285	52.13	5	285	1	264	2.0e-69	255	COG2116	Formate/nitrite transporter FocA, FNT family	265
644852730	760	67.5	2	759	1	755	0.0e+00	1121	COG1882	Pyruvate-formate lyase	755
644852731	246	37.25	1	246	15	257	1.0e-71	262	COG1180	Pyruvate-formate lyase-activating enzyme	260
644852732	313	20.47	6	299	1	292	3.0e-24	106	COG0583	DNA-binding transcriptional regulator, LysR family	297
644852733	382	20.63	14	381	14	394	8.0e-10	58.3	COG2814	Predicted arabinose efflux permease, MFS family	394
644852734	302	27.8	8	296	7	297	1.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
644852735	291	24.48	41	230	30	219	6.0e-17	81.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644852736	214	47.14	1	209	1	208	6.0e-59	220	COG3531	Predicted protein-disulfide isomerase , contains CxxC motif	212
644852737	204	42.56	3	195	7	198	4.0e-40	158	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
644852738	431	60.14	1	431	1	426	0.0e+00	596	COG0172	Seryl-tRNA synthetase	429
644852740	402	50.64	10	400	1	379	2.0e-110	392	COG3328	Transposase (or an inactivated derivative)	379
644852741	434	56.88	3	433	4	436	0.0e+00	584	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
644852743	204	44.76	1	203	4	211	1.0e-42	165	COG2834	Outer membrane lipoprotein-sorting protein	211
644852744	1202	38.44	557	1200	232	856	0.0e+00	508	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
644852745	164	49.35	8	161	2	154	7.0e-38	150	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644852746	318	52.68	4	318	1	305	2.0e-94	339	COG0492	Thioredoxin reductase	305
644852747	589	52.3	23	587	1	557	0.0e+00	622	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
644852748	573	59.55	1	571	1	571	0.0e+00	620	COG4987	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components	573
644852749	242	59.09	13	230	3	221	6.0e-85	307	COG2360	Leu/Phe-tRNA-protein transferase	221
644852750	72	72.22	1	72	1	72	1.0e-25	107	COG0361	Translation initiation factor IF-1	75
644852751	758	48.07	1	745	1	785	0.0e+00	872	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
644852752	106	58.49	1	106	2	107	2.0e-34	137	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
644852753	73	58.21	1	67	1	67	3.0e-23	99.8	COG1278	Cold shock protein, CspA family	67
644852754	553	45.27	1	553	1	580	0.0e+00	485	COG3593	Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains	581
644852755	550	44.74	1	549	4	561	0.0e+00	657	COG1151	Hydroxylamine reductase (hybrid-cluster protein)	576
644852756	335	34.55	5	276	1	266	2.0e-57	216	COG1018	Ferredoxin-NADP reductase	266
644852757	489	24.91	7	285	1	275	3.0e-26	113	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
644852758	289	42.64	21	280	9	257	4.0e-63	235	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
644852759	108	57.94	1	107	1	107	2.0e-32	130	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
644852760	249	85.54	8	249	1	242	3.0e-121	427	COG4161	ABC-type arginine transport system, ATPase component	242
644852761	243	40	1	243	4	265	9.0e-45	173	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644852762	238	51.71	4	237	7	230	1.0e-69	256	COG4215	ABC-type arginine transport system, permease component	230
644852763	223	53.36	1	221	6	228	9.0e-68	250	COG4160	ABC-type arginine/histidine transport system, permease component	228
644852764	249	41.09	4	249	12	266	2.0e-45	175	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644852765	376	34.57	2	368	68	432	7.0e-90	324	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
644852767	281	46.15	1	272	2	267	3.0e-57	215	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
644852768	319	48.29	23	314	1	281	4.0e-75	275	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
644852769	375	51.65	13	375	1	352	2.0e-124	438	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644852770	369	48.38	1	369	4	363	1.0e-97	350	COG0687	Spermidine/putrescine-binding periplasmic protein	363
644852772	300	36.19	1	289	1	314	2.0e-64	239	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
644852773	240	30.1	1	181	2	207	6.0e-21	94.6	COG0778	Nitroreductase	207
644852774	85	36.59	4	85	4	80	6.0e-17	78.9	COG0695	Glutaredoxin	80
644852777	562	50.54	5	558	1	543	0.0e+00	572	COG2985	Uncharacterized membrane protein YbjL, putative transporter	544
644852778	256	35.04	3	256	1	252	9.0e-57	213	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
644852779	402	49.48	14	397	11	389	4.0e-117	414	COG1686	D-alanyl-D-alanine carboxypeptidase	389
644852780	272	16.12	21	272	16	280	3.0e-13	69.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644852781	220	57.94	3	216	9	222	3.0e-70	258	COG2011	ABC-type methionine transport system, permease component	222
644852782	338	55.75	1	336	1	337	2.0e-119	422	COG1135	ABC-type methionine transport system, ATPase component	339
644852783	281	41.54	1	258	1	258	2.0e-70	259	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
644852784	205	30.5	2	197	1	199	2.0e-31	129	COG0625	Glutathione S-transferase	211
644852785	374	45.11	30	373	59	397	1.0e-90	326	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
644852786	467	38.75	33	467	2	436	0.0e+00	494	COG0621	tRNA A37 methylthiotransferase MiaB	437
644852787	251	63	1	225	13	234	5.0e-85	307	COG2949	Uncharacterized periplasmic protein SanA, affects membrane permeability for vancomycin	235
644852788	382	40.72	2	380	16	394	1.0e-65	244	COG2311	Uncharacterized membrane protein YeiB	394
644852789	222	46.46	25	220	1	195	2.0e-65	242	COG0302	GTP cyclohydrolase I	195
644852790	559	39.26	192	515	60	408	4.0e-53	202	COG0840	Methyl-accepting chemotaxis protein	408
644852791	555	38.74	177	515	45	408	2.0e-52	200	COG0840	Methyl-accepting chemotaxis protein	408
644852792	557	38.46	177	515	45	408	6.0e-51	195	COG0840	Methyl-accepting chemotaxis protein	408
644852793	539	35.44	177	515	45	408	3.0e-44	173	COG0840	Methyl-accepting chemotaxis protein	408
644852794	287	34.71	1	284	1	289	5.0e-33	134	COG0583	DNA-binding transcriptional regulator, LysR family	297
644852795	373	69.92	4	372	1	366	0.0e+00	574	COG1062	Zn-dependent alcohol dehydrogenase	366
644852796	281	38.91	1	279	3	313	1.0e-70	259	COG0627	S-formylglutathione hydrolase FrmB	316
644852798	361	35.56	6	358	2	355	1.0e-78	287	COG0371	Glycerol dehydrogenase or related enzyme, iron-containing ADH family	360
644852799	503	45.42	1	500	1	500	0.0e+00	524	COG1129	ABC-type sugar transport system, ATPase component	500
644852800	335	40.62	18	335	1	311	2.0e-48	186	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
644852801	395	44.5	1	389	1	391	4.0e-69	255	COG2814	Predicted arabinose efflux permease, MFS family	394
644852802	490	53.94	11	490	37	517	0.0e+00	614	COG0833	Amino acid permease	541
644852803	292	34.71	3	287	1	288	2.0e-39	156	COG0583	DNA-binding transcriptional regulator, LysR family	297
644852804	361	46.65	15	357	2	334	1.0e-75	277	COG2855	Uncharacterized membrane protein YadS	334
644852805	283	47.16	1	280	1	276	2.0e-96	345	COG0648	Endonuclease IV	280
644852808	563	63.93	227	561	1	339	5.0e-99	355	COG1299	Phosphotransferase system, fructose-specific IIC component	343
644852809	312	48.06	4	312	1	310	5.0e-108	384	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
644852810	379	59.86	2	143	1	142	3.0e-51	195	COG4668	Mannitol/fructose-specific phosphotransferase system, IIA domain	142
644852811	393	21.5	4	388	2	383	2.0e-08	54.4	COG2814	Predicted arabinose efflux permease, MFS family	394
644852813	190	34.59	1	133	3	131	4.0e-29	121	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
644852814	325	29.61	3	325	1	316	1.0e-62	233	COG0523	GTPase, G3E family	323
644852815	191	33.5	2	182	1	197	2.0e-26	112	COG0791	Cell wall-associated hydrolase, NlpC family	197
644852816	603	29	1	596	5	562	1.0e-84	308	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
644852817	365	75.62	1	365	1	364	0.0e+00	583	COG4174	ABC-type microcin C transport system, permease component YejB	364
644852818	341	71.47	1	340	1	340	0.0e+00	518	COG4239	ABC-type microcin C transport system, permease component YejE	341
644852819	530	65.28	1	529	1	530	0.0e+00	785	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
644852821	393	20.89	11	393	14	390	8.0e-19	88.3	COG2814	Predicted arabinose efflux permease, MFS family	394
644852822	232	40.93	1	228	3	239	6.0e-67	247	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
644852824	591	31.87	1	373	33	400	6.0e-76	278	COG1061	Superfamily II DNA or RNA helicase	442
644852825	95	50.53	1	95	1	93	6.0e-22	95.7	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
644852826	405	22.29	58	382	63	397	2.0e-09	57.5	COG2223	Nitrate/nitrite transporter NarK	417
644852827	245	36.99	1	245	2	243	4.0e-54	204	COG3279	DNA-binding response regulator, LytR/AlgR family	244
644852828	566	42.04	5	550	2	549	0.0e+00	578	COG3275	Sensor histidine kinase, LytS/YehU family	557
644852829	336	76.95	1	334	1	334	0.0e+00	521	COG3081	Nucleoid-associated protein YejK (function unknown)	335
644852830	76	67.12	1	73	1	72	1.0e-20	90.8	COG3082	Uncharacterized conserved protein YejL, UPF0352 family	74
644852831	590	57.14	1	590	1	600	0.0e+00	701	COG3083	Membrane-anchored periplasmic protein YejM, alkaline phosphatase superfamily	600
644852833	300	36.03	3	292	2	296	2.0e-41	162	COG0583	DNA-binding transcriptional regulator, LysR family	297
644852834	248	37.8	3	247	2	251	1.0e-45	176	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644852835	224	29.05	6	202	1	201	1.0e-26	112	COG0625	Glutathione S-transferase	211
644852836	81	46.97	1	66	2	67	8.0e-12	62.3	COG3905	Predicted transcriptional regulator	83
644852837	94	31.25	1	94	2	96	2.0e-10	57.4	COG3668	Plasmid stabilization system protein ParE	98
644852838	160	58.12	1	159	2	161	5.0e-67	246	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
644852842	251	46.94	1	244	1	243	1.0e-62	232	COG3967	Short-chain dehydrogenase involved in D-alanine esterification of teichoic acids	245
644852845	143	41.03	2	118	1	117	8.0e-33	132	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
644852846	427	46.35	1	424	3	424	4.0e-90	325	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
644852848	116	50	1	115	3	120	3.0e-24	103	COG3759	Uncharacterized membrane protein	121
644852852	113	67.57	1	111	1	111	3.0e-28	116	COG3136	Uncharacterized membrane protein, GlpM family	111
644852853	434	41.24	1	427	1	397	6.0e-91	328	COG4677	Pectin methylesterase and related acyl-CoA thioesterases	405
644852855	481	21.45	111	481	86	456	3.0e-24	106	COG1538	Outer membrane protein TolC	457
644852856	393	24.1	20	391	3	417	5.0e-23	102	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
644852857	247	44.39	30	247	1	223	3.0e-64	238	COG1136	ABC-type lipoprotein export system, ATPase component	226
644852859	162	40.6	18	148	19	146	4.0e-22	97.4	COG0071	Molecular chaperone IbpA, HSP20 family	146
644852860	431	21.57	16	409	12	401	3.0e-12	66.4	COG1457	Purine-cytosine permease or related protein	442
644852861	335	42.72	13	335	1	312	2.0e-85	309	COG1984	Allophanate hydrolase subunit 2	314
644852862	294	33.47	8	252	1	219	2.0e-54	205	COG2049	Allophanate hydrolase subunit 1	223
644852865	260	47.41	4	252	3	251	6.0e-87	314	COG1540	Lactam utilization protein B (function unknown)	252
644852866	304	31.53	3	294	2	291	9.0e-35	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
644852867	393	35.09	10	386	10	387	1.0e-63	237	COG2807	Cyanate permease	395
644852868	163	35.66	32	159	1	126	7.0e-12	63.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
644852869	170	36.63	1	170	1	199	2.0e-19	88.9	COG3637	Opacity protein and related surface antigens	199
644852870	293	60.14	5	288	4	288	4.0e-69	255	COG5006	Threonine/homoserine efflux transporter RhtA	292
644852871	167	35.71	17	167	4	156	3.0e-34	137	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
644852872	248	35.34	1	246	1	266	2.0e-37	149	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644852873	219	47.96	1	218	1	220	1.0e-51	196	COG0765	ABC-type amino acid transport system, permease component	222
644852874	240	64.17	1	240	2	240	6.0e-108	383	COG1126	ABC-type polar amino acid transport system, ATPase component	240
644852877	621	15.65	15	559	1	543	4.0e-26	113	COG1164	Oligoendopeptidase F	598
644852878	322	28.09	1	319	2	318	7.0e-66	244	COG0547	Anthranilate phosphoribosyltransferase	338
644852879	701	31.61	13	701	2	645	3.0e-116	413	COG1199	Rad3-related DNA helicase	654
644852881	769	35.31	49	455	1	388	2.0e-83	304	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
644852882	446	35.03	8	445	1	447	1.0e-108	386	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
644852883	258	39.24	1	237	1	232	2.0e-52	199	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
644852884	228	27.55	10	196	7	201	7.0e-20	90.7	COG0625	Glutathione S-transferase	211
644852885	319	35.4	3	318	3	315	1.0e-64	240	COG1686	D-alanyl-D-alanine carboxypeptidase	389
644852886	179	33.33	8	178	1	175	3.0e-29	121	COG1437	Adenylate cyclase class IV, CYTH domain (includes archaeal enzymes of unknown function)	178
644852887	135	25.55	3	112	1	137	6.0e-09	53.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644852888	311	39.43	1	311	11	318	4.0e-77	281	COG0042	tRNA-dihydrouridine synthase	323
644852889	531	34.97	9	531	26	554	5.0e-95	341	COG0747	ABC-type transport system, periplasmic component	556
644852890	413	38.35	7	410	5	414	3.0e-99	355	COG2195	Di- or tripeptidase	414
644852894	455	44.49	1	455	29	487	1.0e-119	423	COG0513	Superfamily II DNA and RNA helicase	513
644852895	334	27.66	3	282	12	287	5.0e-33	135	COG1566	Multidrug resistance efflux pump	352
644852896	583	46.43	331	551	4	227	8.0e-71	261	COG1131	ABC-type multidrug transport system, ATPase component	293
644852897	381	34.13	172	379	75	282	6.0e-19	88.8	COG0842	ABC-type multidrug transport system, permease component	286
644852898	374	31.02	71	372	1	282	2.0e-24	106	COG0842	ABC-type multidrug transport system, permease component	286
644852899	256	38.19	11	256	8	257	1.0e-51	196	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
644852900	401	30.4	3	364	54	427	1.0e-55	210	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
644852901	322	25.56	9	318	3	296	3.0e-16	79.6	COG3547	Transposase	303
644852902	236	47.7	1	234	1	228	2.0e-38	152	COG0670	Integral membrane protein, interacts with FtsH	233
644852903	344	37.1	1	336	3	342	2.0e-85	309	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644852904	530	34.32	22	530	3	539	3.0e-72	266	COG1178	ABC-type Fe3+ transport system, permease component	540
644852905	338	25.33	47	338	1	299	8.0e-42	164	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
644852906	150	46.62	1	148	2	149	1.0e-50	192	COG0314	Molybdopterin synthase catalytic subunit	149
644852907	81	47.62	1	81	1	84	6.0e-17	79.2	COG1977	Molybdopterin converting factor, small subunit	84
644852908	160	68.35	1	158	1	157	1.0e-62	232	COG0315	Molybdenum cofactor biosynthesis enzyme	157
644852909	170	47.02	5	170	2	168	3.0e-48	184	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
644852910	340	49.24	15	340	1	322	2.0e-107	382	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
644852912	335	43.31	1	335	3	345	5.0e-73	268	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
644852913	471	49.23	3	453	1	456	0.0e+00	502	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
644852917	306	38.51	3	302	1	309	5.0e-70	257	COG0391	Archaeal 2-phospho-L-lactate transferase/Bacterial gluconeogenesis factor, CofD/UPF0052 family	323
644852919	670	70.9	1	670	1	663	0.0e+00	1117	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
644852920	226	50.88	1	226	1	223	2.0e-71	261	COG0132	Dethiobiotin synthetase	223
644852922	384	44.87	1	384	1	388	5.0e-117	414	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
644852923	346	59.52	1	329	7	335	1.0e-124	439	COG0502	Biotin synthase or related enzyme	335
644852924	427	47.39	1	421	1	441	0.0e+00	545	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
644852925	658	30.12	80	499	1	353	6.0e-43	169	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
644852926	136	44.83	5	120	1	116	5.0e-30	123	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
644852927	231	53.07	1	228	3	230	1.0e-64	239	COG1346	Putative effector of murein hydrolase	230
644852929	295	41.54	52	172	7	134	4.0e-31	128	COG0295	Cytidine deaminase	134
644852930	565	35.27	50	561	1	432	0.0e+00	461	COG0281	Malic enzyme	432
644852931	411	48.04	1	406	1	404	3.0e-127	448	COG0303	Molybdopterin biosynthesis enzyme	404
644852932	252	49.21	3	250	1	254	1.0e-71	263	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
644852933	131	33.88	10	130	8	128	8.0e-31	125	COG1607	Acyl-CoA hydrolase	157
644852934	350	18.95	1	275	4	280	2.0e-10	60.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
644852935	184	30	1	184	3	207	2.0e-22	99.1	COG0655	Multimeric flavodoxin WrbA	207
644852936	57	57.69	1	51	4	55	3.0e-09	53.6	COG0401	Uncharacterized membrane protein YqaE, homolog of Blt101, UPF0057 family	56
644852942	255	58.1	1	249	5	256	3.0e-80	291	COG3228	Mlc titration factor MtfA, regulates ptsG expression	266
644852944	172	44.77	1	172	1	160	2.0e-50	191	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
644852945	618	44.53	1	536	6	542	0.0e+00	556	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
644852946	174	41.41	4	96	3	98	6.0e-11	60.7	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
644852949	294	22.46	14	244	7	224	1.0e-07	51.1	COG2801	Transposase InsO and inactivated derivatives	232
644852951	931	22.15	79	828	8	665	3.0e-28	121	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
644852956	133	59.06	7	133	1	127	2.0e-24	105	COG2916	DNA-binding protein H-NS	128
644852958	183	30.07	1	141	2	144	4.0e-17	81.4	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
644852959	144	32.17	1	141	2	144	1.0e-12	66	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
644852960	311	29.64	7	308	1	297	3.0e-33	135	COG0583	DNA-binding transcriptional regulator, LysR family	297
644852962	103	31.96	3	99	2	95	4.0e-07	46.6	COG3668	Plasmid stabilization system protein ParE	98
644852963	329	28.53	3	314	2	303	5.0e-17	81.9	COG3547	Transposase	303
644852964	244	58.92	3	243	1	240	8.0e-110	389	COG1126	ABC-type polar amino acid transport system, ATPase component	240
644852965	256	44.09	10	229	4	222	5.0e-55	207	COG0765	ABC-type amino acid transport system, permease component	222
644852966	231	37.72	1	227	1	220	2.0e-45	176	COG0765	ABC-type amino acid transport system, permease component	222
644852967	250	39.43	1	237	1	246	3.0e-62	232	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
644852969	307	29	1	299	1	297	3.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
644852970	400	42.61	6	400	1	393	5.0e-105	374	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
644852971	256	51.79	1	251	1	251	3.0e-84	304	COG1540	Lactam utilization protein B (function unknown)	252
644852972	326	50.79	2	315	1	307	1.0e-98	353	COG1984	Allophanate hydrolase subunit 2	314
644852973	229	45.71	22	228	5	214	3.0e-55	208	COG2049	Allophanate hydrolase subunit 1	223
644852974	278	33.09	1	259	2	270	2.0e-34	139	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644852977	320	41.44	201	311	17	127	1.0e-21	97.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644852978	382	37.79	1	382	1	384	1.0e-105	376	COG1979	Alcohol dehydrogenase YqhD, Fe-dependent ADH family	384
644852979	316	40.98	14	316	1	303	5.0e-85	308	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
644852980	298	49.8	10	256	5	250	3.0e-86	312	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
644852981	285	40.88	1	273	1	274	1.0e-48	186	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
644852982	275	46.86	3	272	1	271	1.0e-54	206	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
644852983	310	30.24	7	294	1	284	4.0e-25	108	COG0583	DNA-binding transcriptional regulator, LysR family	297
644852984	302	36.03	1	283	2	298	1.0e-45	177	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
644852986	319	27.19	1	318	1	309	2.0e-20	93.4	COG0679	Predicted permease	311
644852988	277	27.78	5	244	54	288	2.0e-41	162	COG0777	Acetyl-CoA carboxylase beta subunit	294
644852990	285	34.07	16	275	8	280	2.0e-35	142	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
644852992	325	36.09	5	168	3	159	2.0e-28	120	COG0835	Chemotaxis signal transduction protein	165
644852993	595	55.78	1	554	1	538	0.0e+00	703	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
644852994	306	46.62	11	306	1	288	2.0e-65	243	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644852995	324	48.61	1	322	1	317	2.0e-83	302	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644852996	322	42.17	2	312	1	310	4.0e-80	291	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
644852997	316	43.27	3	313	2	310	5.0e-83	301	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
644852998	512	29.87	21	509	42	549	3.0e-75	276	COG0747	ABC-type transport system, periplasmic component	556
644852999	299	25.58	4	298	1	297	1.0e-25	110	COG0583	DNA-binding transcriptional regulator, LysR family	297
644853000	254	43.14	1	254	1	251	8.0e-63	233	COG2134	CDP-diacylglycerol pyrophosphatase	252
644853001	308	22.04	3	305	1	296	4.0e-23	102	COG0583	DNA-binding transcriptional regulator, LysR family	297
644853002	364	26.16	14	349	4	333	9.0e-29	121	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
644853003	566	44.84	55	302	2	253	3.0e-45	176	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
644853004	267	49.19	8	253	2	243	2.0e-81	295	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
644853008	223	56.68	6	222	6	222	1.0e-68	253	COG2011	ABC-type methionine transport system, permease component	222
644853009	263	57.09	1	262	1	268	4.0e-97	347	COG1135	ABC-type methionine transport system, ATPase component	339
644853010	268	49.45	1	265	1	267	2.0e-78	285	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
644853011	344	47.38	4	326	3	322	5.0e-98	351	COG3491	Isopenicillin N synthase and related dioxygenases	322
644853012	257	31.66	1	257	1	232	6.0e-33	134	COG3416	Uncharacterized protein	233
644853013	315	21.89	3	297	1	289	2.0e-25	109	COG0583	DNA-binding transcriptional regulator, LysR family	297
644853016	773	21.27	19	773	9	768	1.0e-33	138	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644853017	345	27.06	9	343	2	327	1.0e-28	120	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
644853018	285	25.6	78	284	42	244	2.0e-11	63.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
644853019	232	38.61	14	210	11	212	8.0e-37	147	COG0811	Biopolymer transport protein ExbB/TolQ	216
644853020	133	38.06	1	133	1	134	4.0e-27	113	COG0848	Biopolymer transport protein ExbD	137
644853021	528	42.21	283	526	12	254	3.0e-46	180	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
644853022	470	37.02	287	467	1	177	2.0e-39	157	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644853023	282	27.01	1	126	2	137	1.0e-06	47.6	COG3153	Predicted N-acetyltransferase YhbS	171
644853024	443	29.26	14	437	1	387	7.0e-51	195	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644853025	268	24.01	2	268	34	333	3.0e-41	162	COG4870	Cysteine protease, C1A family	372
644853029	373	26.14	98	361	3	231	6.0e-24	105	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
644853033	709	37.09	5	695	3	687	0.0e+00	642	COG3345	Alpha-galactosidase	687
644853034	340	34.22	1	337	1	333	9.0e-63	234	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644853035	213	54.85	1	204	1	205	1.0e-57	216	COG2864	Cytochrome b subunit of formate dehydrogenase	218
644853036	302	41.28	21	238	2	202	5.0e-58	218	COG0437	Fe-S-cluster-containing dehydrogenase component	203
644853037	1015	28.19	2	735	1	598	6.0e-97	349	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
644853038	351	35.27	69	322	7	252	1.0e-42	167	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
644853039	119	50.89	7	118	1	110	3.0e-32	130	COG4226	Predicted nuclease of the RNAse H fold, HicB family	111
644853040	207	42.33	39	201	35	195	2.0e-32	132	COG0684	Regulator of RNase E activity RraA	210
644853041	281	51.16	2	259	1	258	3.0e-94	338	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
644853042	349	43.21	30	348	8	330	2.0e-54	206	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
644853043	340	44.65	17	338	7	331	3.0e-56	212	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
644853044	272	31.72	1	264	51	311	9.0e-38	150	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
644853045	329	28.53	3	314	2	303	5.0e-17	81.9	COG3547	Transposase	303
644853046	637	23.16	6	628	4	596	8.0e-54	205	COG4264	Siderophore synthetase component	602
644853047	258	37.05	1	251	2	252	7.0e-59	220	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
644853048	618	31.09	20	611	10	598	1.0e-110	394	COG4264	Siderophore synthetase component	602
644853050	418	30.41	13	395	18	394	2.0e-65	243	COG0019	Diaminopimelate decarboxylase	394
644853051	628	24.83	13	571	17	575	7.0e-50	192	COG4264	Siderophore synthetase component	602
644853052	704	19.22	14	704	39	768	3.0e-34	140	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644853053	460	43.08	1	453	2	446	0.0e+00	494	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
644853054	298	35.82	7	284	7	283	2.0e-49	189	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
644853055	288	34.15	1	284	13	282	2.0e-51	195	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
644853056	310	35.85	1	309	2	298	2.0e-64	239	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
644853057	286	50.77	25	283	1	249	5.0e-86	311	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
644853058	306	31.8	4	305	2	297	1.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
644853059	302	30.91	9	289	3	310	1.0e-55	210	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
644853060	249	28.68	1	245	4	259	2.0e-33	136	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
644853061	186	53.37	1	175	4	180	2.0e-49	188	COG3709	Ribose 1,5-bisphosphokinase PhnN	192
644853062	389	62.7	12	389	1	377	0.0e+00	516	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
644853063	240	70.67	9	233	3	227	1.0e-98	352	COG4778	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL	235
644853064	273	78.57	26	272	5	256	2.0e-116	412	COG4107	ABC-type phosphonate transport system, ATPase component	258
644853065	284	83.39	1	283	6	288	0.0e+00	529	COG3627	Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase	291
644853066	363	73.95	1	356	1	357	0.0e+00	546	COG3626	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI	367
644853067	191	50.78	1	190	4	196	2.0e-54	205	COG3625	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH	196
644853068	149	52	1	148	2	151	2.0e-41	161	COG3624	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG	151
644853069	239	37.34	8	239	5	236	3.0e-49	188	COG2188	DNA-binding transcriptional regulator, GntR family	236
644853070	159	41.88	1	156	1	156	8.0e-39	153	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
644853073	472	45.99	31	454	2	401	1.0e-128	453	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
644853074	478	47.58	7	478	1	469	0.0e+00	488	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644853075	453	56.31	9	451	1	436	0.0e+00	549	COG2704	Anaerobic C4-dicarboxylate transporter	436
644853076	329	26.24	1	253	4	262	2.0e-39	156	COG0673	Predicted dehydrogenase	342
644853077	438	49.88	1	429	1	415	9.0e-107	380	COG1301	Na+/H+-dicarboxylate symporter	415
644853078	317	30	1	298	1	294	3.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
644853079	91	56.25	1	80	1	75	5.0e-19	86.1	COG0298	Hydrogenase maturation factor	82
644853080	208	44.74	1	188	1	156	3.0e-35	141	COG1142	Fe-S-cluster-containing hydrogenase component 2	165
644853081	679	37.6	18	511	10	486	2.0e-70	260	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
644853082	315	46.23	10	313	7	309	6.0e-56	211	COG0650	Formate hydrogenlyase subunit 4	309
644853083	479	36.83	5	478	1	473	3.0e-77	282	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
644853084	216	43.32	1	216	2	218	2.0e-36	145	COG4237	Hydrogenase-4 membrane subunit HyfE	218
644853085	553	36.22	1	510	1	504	6.0e-63	235	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
644853086	575	56.12	185	558	8	382	0.0e+00	488	COG3261	Ni,Fe-hydrogenase III large subunit	382
644853087	189	32.48	1	150	19	171	4.0e-28	117	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
644853088	263	61.22	29	175	1	147	2.0e-61	229	COG3260	Ni,Fe-hydrogenase III small subunit	148
644853090	165	35.03	18	165	6	160	8.0e-21	93.4	COG0680	Ni,Fe-hydrogenase maturation factor	160
644853093	180	49.44	1	180	1	165	8.0e-42	163	COG1142	Fe-S-cluster-containing hydrogenase component 2	165
644853094	716	41.47	1	699	261	957	0.0e+00	681	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
644853095	402	25.69	4	401	1	381	4.0e-45	175	COG2865	Predicted transcriptional regulator, contains HTH domain	467
644853097	723	48.39	194	718	33	549	0.0e+00	504	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
644853098	429	43.06	5	420	7	412	7.0e-90	324	COG1301	Na+/H+-dicarboxylate symporter	415
644853099	213	19.17	11	203	4	192	1.0e-06	47	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644853101	297	24.05	5	292	1	289	7.0e-28	117	COG0583	DNA-binding transcriptional regulator, LysR family	297
644853102	252	28.57	18	238	3	224	8.0e-48	183	COG1794	Aspartate/glutamate racemase	230
644853103	357	41.74	6	333	1	331	2.0e-75	276	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644853104	1036	42.84	53	930	6	808	0.0e+00	677	COG3250	Beta-galactosidase/beta-glucuronidase	808
644853107	255	44.27	6	253	2	251	2.0e-43	169	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644853108	358	28.09	42	358	3	298	1.0e-30	127	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
644853109	416	38.82	13	401	7	393	1.0e-62	233	COG2814	Predicted arabinose efflux permease, MFS family	394
644853110	307	35.94	179	306	1	127	3.0e-23	102	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644853111	203	19.89	39	203	2	186	8.0e-17	80.3	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
644853112	390	33.9	42	389	2	339	2.0e-88	319	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
644853113	232	50	1	223	3	226	2.0e-84	305	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
644853114	263	64.08	19	263	2	246	2.0e-104	371	COG4674	ABC-type uncharacterized transport system, ATPase component	249
644853115	358	37.09	25	356	4	312	3.0e-50	192	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
644853116	525	42.81	226	522	3	295	5.0e-66	245	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
644853117	423	33.77	21	396	1	366	8.0e-71	261	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
644853118	233	25.57	1	218	4	221	2.0e-29	122	COG1802	DNA-binding transcriptional regulator, GntR family	230
644853119	1204	44.37	1	554	1	603	0.0e+00	541	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
644853120	601	32.26	2	447	1	467	2.0e-81	296	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
644853123	110	41.41	6	104	4	98	1.0e-28	118	COG3615	Uncharacterized protein/domain, possibly involved in tellurite resistance	99
644853124	209	21.81	15	199	6	173	1.0e-17	83.5	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
644853126	300	40	14	113	23	122	2.0e-21	96.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644853127	151	26.61	18	140	2	124	1.0e-12	66.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
644853129	270	41.64	6	269	1	269	1.0e-76	279	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
644853130	285	38.95	10	274	18	284	4.0e-59	221	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644853131	311	42.19	1	310	1	317	7.0e-72	264	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644853132	524	30.31	7	522	18	551	7.0e-74	271	COG0747	ABC-type transport system, periplasmic component	556
644853134	732	76.94	1	732	12	730	0.0e+00	1241	COG0376	Catalase (peroxidase I)	730
644853135	138	42.97	5	132	1	128	2.0e-24	104	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
644853136	231	55.95	1	227	3	229	1.0e-67	249	COG1346	Putative effector of murein hydrolase	230
644853137	265	38.79	151	265	3	118	1.0e-19	90.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644853138	382	50.88	97	372	1	283	4.0e-97	348	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
644853140	475	54.51	4	464	1	459	0.0e+00	618	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
644853141	231	40.69	1	231	1	218	6.0e-55	207	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
644853142	578	34.55	2	485	1	510	4.0e-97	349	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644853143	254	32.27	4	251	2	251	3.0e-14	72.4	COG0730	Uncharacterized membrane protein YfcA	258
644853144	374	32.06	22	358	2	334	6.0e-36	145	COG0642	Signal transduction histidine kinase	336
644853145	245	43.04	18	243	3	227	3.0e-50	192	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644853146	420	29.29	33	406	1	368	5.0e-32	132	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644853147	1044	50.34	1	1022	2	1007	0.0e+00	965	COG0841	Multidrug efflux pump subunit AcrB	1009
644853148	288	25.09	1	271	2	266	6.0e-22	98.4	COG2162	Arylamine N-acetyltransferase	275
644853150	304	27.84	1	286	1	291	2.0e-33	136	COG0583	DNA-binding transcriptional regulator, LysR family	297
644853151	501	21.71	65	451	52	394	3.0e-11	63.7	COG2814	Predicted arabinose efflux permease, MFS family	394
644853152	75	80.82	1	73	1	73	2.0e-23	100	COG3813	Uncharacterized protein	84
644853153	437	42.48	61	437	11	352	1.0e-90	327	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
644853154	373	69.15	1	373	1	376	0.0e+00	483	COG2822	Iron uptake system EfeUOB, periplasmic (or lipoprotein) component EfeO/EfeM	376
644853155	281	40.6	1	267	7	304	9.0e-48	184	COG0672	High-affinity Fe2+/Pb2+ permease	383
644853157	329	38.39	23	327	31	333	2.0e-68	252	COG3367	Uncharacterized conserved protein, NAD-dependent epimerase/dehydratase family	339
644853158	336	31.71	1	305	3	328	2.0e-43	170	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644853159	286	34.86	3	281	2	281	2.0e-57	215	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
644853160	192	21.59	1	176	5	180	5.0e-08	51.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644853163	455	24.5	144	431	33	282	3.0e-10	60.1	COG0790	TPR repeat	292
644853165	1165	34.12	18	1165	13	1188	0.0e+00	793	COG3523	Type VI protein secretion system component VasK	1188
644853166	479	25.2	228	479	34	285	1.0e-15	77.8	COG3515	Predicted component of the type VI protein secretion system	346
644853169	872	39.1	12	871	1	784	0.0e+00	743	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
644853170	258	44.87	27	257	26	259	1.0e-62	233	COG3455	Type VI protein secretion system component VasF	262
644853171	445	53.14	1	444	1	446	0.0e+00	513	COG3522	Predicted component of the type VI protein secretion system	446
644853172	178	32.93	11	176	9	159	7.0e-31	126	COG3521	Predicted component of the type VI protein secretion system	159
644853173	409	36.45	7	406	3	428	1.0e-69	256	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
644853174	337	44.59	21	333	17	328	7.0e-82	297	COG3520	Predicted component of the type VI protein secretion system	335
644853175	588	37.86	1	585	3	618	0.0e+00	515	COG3519	Type VI protein secretion system component VasA	621
644853176	143	32.88	7	141	7	152	8.0e-20	89.6	COG3518	Predicted component of the type VI protein secretion system	157
644853177	492	55.06	1	492	4	493	0.0e+00	728	COG3517	Predicted component of the type VI protein secretion system	495
644853178	167	47.83	9	167	9	168	2.0e-43	168	COG3516	Predicted component of the type VI protein secretion system	169
644853179	385	45.71	6	385	9	392	5.0e-115	408	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
644853183	1673	22.12	852	1563	2	660	3.0e-34	141	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
644853188	1679	21.43	852	1578	2	675	3.0e-35	145	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
644853194	456	42.86	1	100	1	98	7.0e-13	68.8	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
644853195	678	42.75	1	542	6	547	0.0e+00	531	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
644853196	172	44.77	1	172	1	160	2.0e-50	191	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
644853197	485	26.24	205	464	1	233	1.0e-46	181	COG0775	Nucleoside phosphorylase	234
644853199	161	46.36	11	161	6	156	5.0e-42	163	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
644853200	380	30.58	28	378	5	346	6.0e-63	235	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
644853201	808	19.78	77	808	49	699	8.0e-33	136	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
644853202	264	50.19	9	263	2	258	8.0e-73	267	COG4559	ABC-type hemin transport system, ATPase component	259
644853203	329	45.09	7	329	8	332	2.0e-51	196	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
644853204	271	46.04	1	266	17	294	2.0e-62	232	COG4558	ABC-type hemin transport system, periplasmic component	300
644853205	343	59.53	5	343	10	349	2.0e-121	429	COG3720	Putative heme degradation protein	349
644853207	316	34.97	1	304	7	300	6.0e-51	194	COG2990	Uncharacterized protein VirK/YbjX	300
644853208	253	37.4	15	253	7	251	4.0e-40	158	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644853209	298	30.14	85	290	15	219	1.0e-20	94	COG1802	DNA-binding transcriptional regulator, GntR family	230
644853216	468	70.43	1	468	1	469	0.0e+00	809	COG0362	6-phosphogluconate dehydrogenase	473
644853217	299	49.83	1	299	2	291	8.0e-98	350	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
644853218	388	39.52	1	388	1	414	2.0e-124	439	COG1004	UDP-glucose 6-dehydrogenase	414
644853219	335	30.14	1	335	1	314	2.0e-52	199	COG0451	Nucleoside-diphosphate-sugar epimerase	314
644853220	457	38.44	1	456	4	459	1.0e-108	386	COG1109	Phosphomannomutase	464
644853221	476	52.52	4	338	2	332	3.0e-129	455	COG0836	Mannose-1-phosphate guanylyltransferase	333
644853222	278	20.22	1	256	2	266	7.0e-07	48.2	COG1216	Glycosyltransferase, GT2 family	305
644853223	423	19.43	1	422	2	423	7.0e-15	75.5	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
644853225	285	51.4	1	285	1	281	2.0e-91	329	COG1091	dTDP-4-dehydrorhamnose reductase	281
644853226	178	62.29	1	175	1	173	7.0e-62	229	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
644853227	289	58.74	1	286	1	283	1.0e-115	409	COG1209	dTDP-glucose pyrophosphorylase	286
644853228	354	66.57	1	352	1	338	0.0e+00	577	COG1088	dTDP-D-glucose 4,6-dehydratase	340
644853229	468	43.97	238	468	1	226	2.0e-71	263	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
644853231	343	26.63	10	343	29	376	6.0e-30	125	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644853232	400	18.18	2	384	1	378	3.0e-14	73.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644853233	382	20.25	2	381	1	379	2.0e-18	87	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644853234	723	28.98	15	455	9	458	1.0e-56	214	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
644853235	144	37.06	1	142	1	138	4.0e-30	123	COG0394	Protein-tyrosine-phosphatase	139
644853236	378	48.54	48	286	9	239	4.0e-54	205	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
644853237	529	51.87	1	237	8	248	1.0e-71	264	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
644853238	604	26.92	1	596	4	621	6.0e-61	229	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
644853239	193	47.15	1	192	1	183	1.0e-52	199	COG0717	Deoxycytidine triphosphate deaminase	183
644853240	213	54.93	1	213	1	209	1.0e-75	275	COG0572	Uridine kinase	218
644853241	369	42.45	49	323	3	265	3.0e-60	226	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
644853242	677	42.78	2	548	1	558	0.0e+00	685	COG0143	Methionyl-tRNA synthetase	558
644853245	358	22.82	14	306	6	297	3.0e-23	102	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
644853246	416	46.72	6	416	8	370	2.0e-122	432	COG5276	Uncharacterized conserved protein	370
644853247	331	46.13	1	329	1	346	9.0e-101	360	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
644853248	273	34.07	1	269	1	259	9.0e-54	203	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
644853249	352	69.32	1	352	1	352	0.0e+00	497	COG4148	ABC-type molybdate transport system, ATPase component	352
644853250	229	59.29	3	228	1	225	4.0e-69	254	COG4149	ABC-type molybdate transport system, permease component	225
644853251	261	43.37	9	256	12	256	3.0e-60	225	COG0725	ABC-type molybdate transport system, periplasmic component	258
644853253	269	59.23	1	130	1	130	4.0e-41	161	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
644853254	489	50.39	230	486	1	257	7.0e-82	298	COG1119	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA	257
644853255	338	48.52	1	336	1	329	0.0e+00	490	COG1087	UDP-glucose 4-epimerase	329
644853256	362	57.35	9	344	1	336	3.0e-120	425	COG1085	Galactose-1-phosphate uridylyltransferase	338
644853257	383	54.9	1	382	3	389	0.0e+00	484	COG0153	Galactokinase	390
644853258	356	37.13	16	352	6	307	2.0e-54	206	COG2017	Galactose mutarotase or related enzyme	308
644853260	136	29.89	49	133	23	108	5.0e-08	50.1	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
644853261	419	19.85	22	418	37	448	1.0e-10	61.3	COG1538	Outer membrane protein TolC	457
644853262	507	24.92	88	385	32	356	6.0e-18	85.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644853263	1045	51.1	1	1044	1	1027	0.0e+00	1232	COG3696	Cu/Ag efflux pump CusA	1027
644853264	250	66.09	3	232	1	230	4.0e-102	364	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
644853265	350	69.43	1	349	1	350	0.0e+00	599	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
644853266	241	39.66	4	239	8	222	4.0e-45	175	COG3201	Nicotinamide riboside transporter PnuC	222
644853267	349	47.16	12	345	5	324	4.0e-113	401	COG0379	Quinolinate synthase	324
644853268	239	36.13	1	238	1	227	7.0e-40	157	COG1811	Uncharacterized membrane protein YqgA, affects biofilm formation	228
644853271	272	48.91	1	272	1	261	2.0e-58	219	COG1729	Periplasmic TolA-binding protein (function unknown)	262
644853272	168	32.97	1	168	3	187	7.0e-36	143	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
644853273	428	49.88	9	428	1	425	7.0e-114	404	COG0823	Periplasmic component of the Tol biopolymer transport system	425
644853274	399	52.38	1	398	1	387	2.0e-18	87.2	COG3064	Membrane protein involved in colicin uptake	387
644853275	141	39.01	1	141	2	135	3.0e-28	117	COG0848	Biopolymer transport protein ExbD	137
644853276	228	43.52	9	224	1	216	1.0e-51	196	COG0811	Biopolymer transport protein ExbB/TolQ	216
644853277	134	39.55	1	134	1	133	1.0e-31	128	COG0824	Acyl-CoA thioesterase FadM	137
644853278	96	64.89	3	96	4	97	9.0e-28	114	COG3790	Predicted membrane protein, encoded in cydAB operon	97
644853279	38	57.14	1	35	1	35	1.0e-06	45	COG4890	Predicted outer membrane lipoprotein	37
644853280	379	48.41	1	374	1	346	2.0e-93	336	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
644853282	290	70.45	1	290	1	291	3.0e-124	438	COG0074	Succinyl-CoA synthetase, alpha subunit	293
644853283	388	65.38	1	388	1	387	0.0e+00	554	COG0045	Succinyl-CoA synthetase, beta subunit	387
644853284	408	51.94	2	407	1	404	1.0e-117	417	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
644853285	935	65.88	6	934	1	906	0.0e+00	1455	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
644853286	238	55.04	1	237	1	231	1.0e-84	306	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
644853287	588	55.36	3	573	2	561	0.0e+00	657	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
644853288	115	44.35	1	115	2	116	8.0e-19	85.6	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
644853289	129	44.88	7	129	1	127	2.0e-17	81.5	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
644853290	428	54.34	27	428	1	390	0.0e+00	501	COG0372	Citrate synthase	390
644853291	245	62.65	1	244	2	250	1.0e-92	332	COG1540	Lactam utilization protein B (function unknown)	252
644853292	309	54.02	2	307	1	311	2.0e-112	398	COG1984	Allophanate hydrolase subunit 2	314
644853293	219	52.31	6	219	1	216	2.0e-68	252	COG2049	Allophanate hydrolase subunit 1	223
644853294	247	42.8	1	247	1	250	1.0e-71	262	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
644853295	476	51.05	1	471	1	461	0.0e+00	519	COG0415	Deoxyribodipyrimidine photolyase	461
644853296	319	65.43	158	319	1	161	2.0e-58	219	COG3272	Uncharacterized conserved protein YbgA, DUF1722 family	163
644853298	561	66.01	6	556	5	559	0.0e+00	725	COG2060	K+-transporting ATPase, A chain	560
644853299	688	72.86	3	688	2	681	0.0e+00	1057	COG2216	High-affinity K+ transport system, ATPase chain B	681
644853300	191	57.67	1	187	2	190	1.0e-59	222	COG2156	K+-transporting ATPase, c chain	190
644853301	909	52.43	4	906	1	889	0.0e+00	1053	COG2205	K+-sensing histidine kinase KdpD	890
644853302	229	43.61	7	229	2	227	5.0e-57	214	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644853303	142	45.77	1	142	1	140	3.0e-22	97.6	COG2510	Uncharacterized membrane protein	140
644853304	547	68.89	25	547	1	524	0.0e+00	769	COG0033	Phosphoglucomutase	524
644853305	179	70.72	1	179	1	181	1.0e-71	262	COG3057	Negative regulator of replication initiation	181
644853306	260	23.84	1	259	2	281	4.0e-18	85.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644853308	564	36.12	136	517	2	408	9.0e-52	198	COG0840	Methyl-accepting chemotaxis protein	408
644853309	175	45.88	1	168	1	151	3.0e-34	138	COG0716	Flavodoxin	151
644853310	148	49.31	1	144	5	145	2.0e-38	151	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
644853311	552	36.02	20	529	1	472	2.0e-116	413	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
644853312	490	34.94	1	403	3	393	4.0e-70	259	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
644853313	266	40.4	1	249	1	238	2.0e-64	239	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
644853314	383	53.52	1	380	1	379	1.0e-129	456	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
644853315	407	30.28	82	406	2	314	1.0e-51	197	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
644853316	554	37.57	1	553	1	542	0.0e+00	488	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
644853323	109	47.12	1	104	2	105	1.0e-21	95.1	COG2076	Multidrug transporter EmrE and related cation transporters	106
644853324	388	32.06	1	388	1	385	5.0e-78	285	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
644853325	476	51.13	3	442	1	436	0.0e+00	557	COG0621	tRNA A37 methylthiotransferase MiaB	437
644853326	350	55.82	7	340	15	348	2.0e-122	432	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
644853327	161	49.02	4	153	1	153	8.0e-41	159	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
644853328	289	76.71	1	289	1	292	1.0e-121	429	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
644853329	509	42.31	1	509	5	514	4.0e-121	428	COG0815	Apolipoprotein N-acyltransferase	518
644853330	297	29.29	3	276	1	273	2.0e-35	143	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644853331	246	33.05	9	241	2	222	2.0e-46	179	COG0765	ABC-type amino acid transport system, permease component	222
644853332	224	42.41	2	222	1	217	5.0e-48	184	COG0765	ABC-type amino acid transport system, permease component	222
644853333	241	63.75	1	240	2	240	2.0e-109	388	COG1126	ABC-type polar amino acid transport system, ATPase component	240
644853335	860	53.58	1	859	1	814	0.0e+00	1108	COG0495	Leucyl-tRNA synthetase	814
644853336	184	52.49	1	180	1	178	6.0e-47	180	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
644853337	343	36.53	4	334	1	333	4.0e-69	255	COG1466	DNA polymerase III, delta subunit	334
644853338	219	48.58	9	219	3	196	3.0e-58	218	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
644853339	105	52.38	1	105	1	105	2.0e-36	143	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
644853340	156	50.97	1	155	1	155	3.0e-62	230	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
644853341	636	36.23	6	619	1	593	0.0e+00	488	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
644853342	370	45.16	11	370	9	379	3.0e-85	309	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
644853343	381	35.22	5	228	7	233	3.0e-41	162	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
644853344	403	50.25	11	402	3	389	3.0e-117	415	COG1686	D-alanyl-D-alanine carboxypeptidase	389
644853345	87	74.16	1	87	2	90	4.0e-33	132	COG2921	Putative lipoic acid-binding regulatory protein	90
644853346	244	57	14	218	9	215	9.0e-80	289	COG0321	Lipoate-protein ligase B	221
644853347	321	66.02	13	321	1	306	0.0e+00	500	COG0320	Lipoate synthase	306
644853349	262	35.42	1	262	3	271	3.0e-47	181	COG0388	Predicted amidohydrolase	274
644853350	127	44	1	124	1	125	8.0e-22	96	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
644853351	69	71.64	3	69	1	67	9.0e-26	108	COG1278	Cold shock protein, CspA family	67
644853352	127	39.5	1	116	1	115	1.0e-29	122	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
644853353	375	34.17	1	375	11	408	1.0e-85	310	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644853354	224	36.67	3	206	27	235	2.0e-42	165	COG1876	LD-carboxypeptidase LdcB, LAS superfamily	241
644853356	228	24.53	1	209	3	207	6.0e-29	120	COG0400	Predicted esterase	207
644853357	676	35.05	3	662	19	736	0.0e+00	516	COG1444	tRNA(Met) C34 N-acetyltransferase TmcA	758
644853358	150	59.86	4	150	2	148	2.0e-34	138	COG2707	Uncharacterized membrane protein, DUF441 family	151
644853359	237	54.81	1	237	1	239	5.0e-83	300	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
644853360	346	49.27	6	344	1	342	2.0e-93	336	COG3317	Uncharacterized lipoprotein	342
644853361	292	50.34	1	292	4	297	5.0e-96	344	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
644853362	204	59.09	19	194	1	176	1.0e-60	225	COG2716	Glycine cleavage system regulatory protein	176
644853363	155	53.25	1	154	1	154	6.0e-57	213	COG1225	Peroxiredoxin	157
644853364	487	49.69	1	486	1	484	0.0e+00	482	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
644853365	118	41.38	3	118	1	115	3.0e-34	137	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
644853367	429	40.63	6	417	7	444	7.0e-83	301	COG2233	Xanthine/uracil permease	451
644853368	208	65.07	1	208	2	210	4.0e-80	290	COG0035	Uracil phosphoribosyltransferase	210
644853369	345	66.76	4	344	1	343	0.0e+00	530	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
644853370	212	53.5	2	201	1	200	1.0e-79	289	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
644853371	332	40.36	2	332	1	332	2.0e-86	313	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644853372	331	32.62	6	331	14	317	1.0e-39	157	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
644853373	506	47.8	7	503	2	498	0.0e+00	649	COG1129	ABC-type sugar transport system, ATPase component	500
644853374	336	84.52	1	336	1	336	0.0e+00	481	COG4211	ABC-type glucose/galactose transport system, permease component	336
644853375	273	36.62	1	273	1	272	1.0e-35	143	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644853376	281	45.12	59	272	8	222	1.0e-53	203	COG0765	ABC-type amino acid transport system, permease component	222
644853377	369	29.36	17	339	33	319	3.0e-40	159	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
644853378	721	22.8	14	721	17	719	1.0e-66	248	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
644853379	186	32	8	172	10	184	3.0e-23	101	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644853380	810	49.64	1	808	6	829	0.0e+00	847	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
644853381	228	74.12	1	228	1	228	3.0e-92	331	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
644853382	182	33	2	182	13	215	2.0e-25	108	COG2755	Lysophospholipase L1 or related esterase	216
644853383	258	30.53	1	255	5	257	2.0e-39	156	COG0300	Short-chain dehydrogenase	265
644853384	286	53.19	6	286	23	304	9.0e-82	296	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
644853385	397	43.32	1	245	1	245	2.0e-69	257	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
644853387	462	31.2	1	456	10	524	3.0e-75	275	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644853388	322	71.34	1	320	1	321	0.0e+00	481	COG1441	O-succinylbenzoate synthase	321
644853389	285	74.82	6	285	1	282	0.0e+00	523	COG0447	1,4-Dihydroxy-2-naphthoyl-CoA synthase	282
644853390	263	23.95	11	250	19	279	5.0e-14	71.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644853391	558	47.26	1	555	1	561	0.0e+00	621	COG1165	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase	566
644853392	441	43.31	33	439	24	422	2.0e-99	356	COG1169	Isochorismate synthase EntC	423
644853393	889	26.27	418	671	91	336	3.0e-21	97.5	COG0642	Signal transduction histidine kinase	336
644853394	216	32.7	4	210	1	208	4.0e-40	157	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644853395	955	36.48	454	696	97	332	3.0e-41	164	COG0642	Signal transduction histidine kinase	336
644853396	877	59.69	1	842	1	803	0.0e+00	1083	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
644853397	249	60.09	19	248	11	242	1.0e-92	332	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
644853398	762	35.3	41	745	1	648	0.0e+00	601	COG0209	Ribonucleotide reductase alpha subunit	696
644853399	376	35.83	2	371	1	346	8.0e-93	334	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
644853400	86	26.88	1	85	2	94	1.0e-10	57.8	COG0633	Ferredoxin	102
644853401	304	41.67	1	293	2	291	2.0e-52	199	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
644853402	151	51.45	10	147	5	139	1.0e-27	115	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
644853403	137	33.02	1	105	1	106	6.0e-20	90.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
644853404	939	43.15	193	931	1	712	0.0e+00	720	COG2217	Cation transport ATPase	713
644853405	270	32.98	1	265	9	290	6.0e-54	204	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
644853406	159	56.96	1	158	1	155	7.0e-41	159	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
644853407	467	28.78	16	450	55	536	5.0e-51	195	COG5434	Polygalacturonase	542
644853408	529	36.78	191	512	61	408	1.0e-45	177	COG0840	Methyl-accepting chemotaxis protein	408
644853409	550	33.87	11	549	3	514	4.0e-97	349	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
644853410	561	75.74	6	409	5	408	0.0e+00	522	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
644853411	320	47.52	1	319	1	317	9.0e-108	383	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
644853412	214	42.2	1	214	1	178	6.0e-50	190	COG0563	Adenylate kinase or related kinase	178
644853413	629	65.39	3	628	1	619	0.0e+00	878	COG0326	Molecular chaperone, HSP90 family	623
644853414	201	57.79	1	199	1	198	1.0e-84	305	COG0353	Recombinational DNA repair protein RecR	198
644853415	109	59.81	1	106	1	105	3.0e-27	113	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
644853416	678	45.63	1	508	1	513	0.0e+00	488	COG2812	DNA polymerase III, gamma/tau subunits	515
644853417	182	51.96	3	181	1	179	4.0e-50	190	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
644853418	122	48.74	1	118	1	119	9.0e-24	102	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
644853419	256	47.98	6	252	5	203	2.0e-66	246	COG4445	tRNA isopentenyl-2-thiomethyl-A-37 hydroxylase MiaE (synthesis of 2-methylthio-cis-ribozeatin)	203
644853420	177	51.15	1	174	1	174	1.0e-26	113	COG3923	Primosomal replication protein N''	175
644853422	1133	42.18	233	1121	1	823	0.0e+00	726	COG3264	Small-conductance mechanosensitive channel	835
644853423	216	24.15	1	207	2	201	2.0e-12	65.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644853424	396	37.24	3	382	2	372	3.0e-38	152	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644853425	1047	55.81	1	1029	2	1009	0.0e+00	1075	COG0841	Multidrug efflux pump subunit AcrB	1009
644853426	83	38.55	1	82	1	72	2.0e-16	77.6	COG0254	Ribosomal protein L31	75
644853430	108	60.4	4	104	3	103	1.0e-33	134	COG3695	Alkylated DNA nucleotide flippase Atl1, participates in nucleotide excision repair, Ada-like DNA-binding domain	103
644853431	185	43.29	1	164	1	158	6.0e-28	117	COG3126	Uncharacterized lipoprotein YbaY	158
644853432	287	63.16	1	285	1	285	1.0e-111	396	COG1946	Acyl-CoA thioesterase	289
644853433	430	54.7	30	429	2	403	5.0e-116	411	COG0004	Ammonia channel protein AmtB	409
644853434	112	66.96	1	112	1	112	2.0e-38	150	COG0347	Nitrogen regulatory protein PII	112
644853435	597	39.16	8	576	1	565	3.0e-120	426	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
644853436	588	37.8	1	574	1	567	2.0e-129	456	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
644853437	153	43.05	1	151	5	154	2.0e-37	147	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644853438	349	28.34	13	322	2	300	3.0e-80	292	COG0031	Cysteine synthase	300
644853439	231	49.07	1	213	2	211	1.0e-75	276	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
644853441	626	27.31	194	414	93	317	2.0e-06	48.6	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
644853442	90	62.22	1	90	2	91	9.0e-29	118	COG0776	Bacterial nucleoid DNA-binding protein	94
644853443	787	71.67	2	778	1	780	0.0e+00	1248	COG0466	ATP-dependent Lon protease, bacterial type	782
644853444	424	75.25	16	419	1	403	0.0e+00	714	COG1219	ATP-dependent protease Clp, ATPase subunit	408
644853445	207	76.29	14	207	1	194	8.0e-90	322	COG0740	ATP-dependent protease ClpP, protease subunit	200
644853446	434	48.18	1	430	1	439	8.0e-113	400	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
644853447	104	60	1	84	3	87	5.0e-25	105	COG0271	Stress-induced morphogen (activity unknown)	90
644853448	192	60.42	1	192	14	204	2.0e-59	221	COG3056	Uncharacterized lipoprotein YajG	204
644853449	489	23.15	77	411	75	394	2.0e-09	57.9	COG2814	Predicted arabinose efflux permease, MFS family	394
644853450	317	46.88	12	267	2	247	1.0e-71	263	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
644853451	663	55.57	38	608	1	566	0.0e+00	633	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
644853452	204	50	6	204	12	209	9.0e-51	193	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
644853453	110	66.06	1	108	1	109	2.0e-25	107	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
644853454	297	44.64	1	289	16	302	2.0e-82	299	COG0109	Polyprenyltransferase (heme O synthase)	304
644853455	457	21.68	4	388	1	384	3.0e-24	106	COG2814	Predicted arabinose efflux permease, MFS family	394
644853456	163	74.23	1	163	4	165	3.0e-62	230	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
644853457	306	38.71	1	299	1	307	9.0e-64	237	COG1893	Ketopantoate reductase	307
644853458	198	31.75	1	178	1	188	8.0e-26	110	COG0693	Putative intracellular protease/amidase	188
644853459	482	41.19	1	384	2	383	8.0e-115	407	COG0301	Adenylyl- and sulfurtransferase ThiI, participates in tRNA 4-thiouridine and thiamine biosynthesis	383
644853460	82	51.9	2	80	3	81	3.0e-12	63.4	COG1722	Exonuclease VII small subunit	81
644853461	303	37.72	3	303	2	322	5.0e-64	237	COG0142	Geranylgeranyl pyrophosphate synthase	322
644853462	620	62.86	8	620	2	623	0.0e+00	971	COG1154	Deoxyxylulose-5-phosphate synthase	627
644853463	170	48.39	15	166	8	160	6.0e-41	160	COG1267	Phosphatidylglycerophosphatase A	160
644853464	324	52.62	1	322	1	317	3.0e-99	355	COG0611	Thiamine monophosphate kinase	317
644853465	139	54.48	2	139	6	150	5.0e-39	153	COG0781	Transcription termination factor NusB	151
644853466	157	62.91	1	151	1	150	1.0e-52	198	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
644853467	370	74.66	1	146	1	146	3.0e-66	245	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
644853468	149	59.73	1	149	1	149	6.0e-57	213	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
644853469	903	33.98	35	903	6	917	0.0e+00	707	COG0474	Magnesium-transporting ATPase (P-type)	917
644853471	323	50.16	8	314	1	304	5.0e-92	331	COG0341	Preprotein translocase subunit SecF	305
644853472	604	51.93	64	604	1	506	0.0e+00	476	COG0342	Preprotein translocase subunit SecD	506
644853473	111	44.9	14	111	1	97	1.0e-26	111	COG1862	Preprotein translocase subunit YajC	97
644853474	387	65.77	3	373	1	370	0.0e+00	586	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
644853475	357	60.91	3	351	1	348	0.0e+00	522	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
644853476	201	62.18	1	193	1	193	1.0e-67	249	COG3124	Acyl carrier protein phosphodiesterase	193
644853477	200	57.65	1	196	2	194	4.0e-75	274	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
644853478	450	54.69	2	449	6	452	0.0e+00	519	COG1113	L-asparagine transporter and related permeases	462
644853479	440	53.6	5	433	1	431	5.0e-127	448	COG1114	Branched-chain amino acid permeases	431
644853480	368	23.97	5	367	2	327	1.0e-59	224	COG0620	Methionine synthase II (cobalamin-independent)	330
644853481	324	33.12	1	301	13	318	4.0e-49	188	COG0226	ABC-type phosphate transport system, periplasmic component	318
644853482	440	32.64	98	422	111	447	9.0e-48	184	COG5002	Signal transduction histidine kinase	459
644853483	229	47.37	4	227	2	227	8.0e-63	233	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644853484	410	27.8	1	402	1	388	3.0e-59	222	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
644853485	1227	22.24	1	785	1	777	1.0e-41	165	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
644853486	303	35.28	1	299	7	305	3.0e-56	211	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
644853487	303	70.53	2	303	1	302	3.0e-128	451	COG2974	DNA recombination-dependent growth factor C	303
644853488	596	37.18	275	596	64	408	1.0e-49	191	COG0840	Methyl-accepting chemotaxis protein	408
644853489	94	71.28	1	94	1	94	7.0e-35	138	COG3123	Uncharacterized conserved protein YaiE, UPF0345 family	94
644853490	173	38.24	1	169	1	167	5.0e-45	173	COG0703	Shikimate kinase	172
644853491	348	41.74	11	345	5	346	1.0e-85	309	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
644853492	366	24.86	8	361	2	327	3.0e-50	192	COG0620	Methionine synthase II (cobalamin-independent)	330
644853493	395	22.37	87	305	16	236	5.0e-15	75.7	COG1647	Esterase/lipase	243
644853494	218	33.18	1	213	5	202	2.0e-38	152	COG0560	Phosphoserine phosphatase	212
644853495	313	30.46	1	300	1	297	9.0e-32	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
644853496	475	21.6	16	457	12	409	1.0e-32	134	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644853497	424	19.15	49	423	43	391	5.0e-08	52.5	COG2814	Predicted arabinose efflux permease, MFS family	394
644853499	176	42.35	3	171	1	169	3.0e-41	161	COG1247	L-amino acid N-acyltransferase YncA	169
644853500	293	31.16	4	291	1	290	8.0e-38	150	COG0583	DNA-binding transcriptional regulator, LysR family	297
644853505	241	41.67	62	234	1	180	2.0e-37	149	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644853506	113	69.64	2	113	1	112	7.0e-45	172	COG2824	Uncharacterized Zn-ribbon-containing protein	112
644853508	587	28.67	5	279	14	290	3.0e-33	137	COG3207	Pyoverdine/dityrosine biosynthesis protein Dit1	330
644853509	226	31.46	5	215	5	217	2.0e-33	136	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
644853510	335	37.55	58	327	45	317	6.0e-46	178	COG3207	Pyoverdine/dityrosine biosynthesis protein Dit1	330
644853511	206	39.55	27	203	7	173	8.0e-36	143	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
644853512	282	31.09	164	281	1	119	5.0e-15	75.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644853513	296	28.43	5	290	1	298	3.0e-42	165	COG1893	Ketopantoate reductase	307
644853514	197	21.81	4	190	14	201	2.0e-06	46.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644853515	246	43.78	4	243	3	249	2.0e-37	149	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644853516	183	41.82	63	170	7	116	4.0e-14	71.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
644853517	244	33.16	1	191	2	194	1.0e-28	120	COG2085	Predicted dinucleotide-binding enzyme	211
644853518	237	25.12	15	221	1	192	4.0e-14	71.9	COG0778	Nitroreductase	207
644853519	852	53.39	5	849	1	842	0.0e+00	1029	COG0249	DNA mismatch repair ATPase MutS	843
644853521	182	61.8	1	178	1	178	4.0e-68	250	COG4681	Uncharacterized conserved protein YaeQ, suppresses RfaH defect	181
644853523	86	62.65	3	85	1	83	4.0e-26	109	COG4568	Transcriptional antiterminator Rof (Rho-off)	84
644853524	442	32.54	5	291	4	287	7.0e-46	178	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
644853525	129	27.54	5	128	1	138	6.0e-11	59.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644853526	319	67.92	2	319	1	315	0.0e+00	512	COG0825	Acetyl-CoA carboxylase alpha subunit	317
644853527	1160	51.63	3	1158	1	1139	0.0e+00	1406	COG0587	DNA polymerase III, alpha subunit	1139
644853528	198	60.53	13	198	2	191	1.0e-68	252	COG0164	Ribonuclease HII	199
644853529	383	56.2	5	379	1	378	0.0e+00	488	COG0763	Lipid A disaccharide synthetase	381
644853530	262	62.31	3	262	1	260	3.0e-111	394	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
644853531	151	59.86	7	151	3	147	3.0e-49	187	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
644853532	340	56.05	1	337	1	338	2.0e-110	392	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
644853533	165	49.4	1	165	1	168	1.0e-25	109	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
644853534	805	45.72	1	805	1	766	0.0e+00	777	COG4775	Outer membrane protein assembly factor BamA	766
644853536	285	35.11	1	281	1	264	3.0e-39	155	COG0575	CDP-diglyceride synthetase	265
644853537	253	55.7	9	245	9	245	6.0e-91	327	COG0020	Undecaprenyl pyrophosphate synthase	245
644853538	397	60.35	1	395	1	382	0.0e+00	565	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
644853539	185	63.78	1	185	3	187	1.0e-67	249	COG0233	Ribosome recycling factor	187
644853540	243	60.92	5	241	1	238	2.0e-93	335	COG0528	Uridylate kinase	238
644853541	285	60.14	1	284	1	296	2.0e-94	339	COG0264	Translation elongation factor EF-Ts	296
644853542	241	64.68	1	235	1	234	6.0e-101	360	COG0052	Ribosomal protein S2	252
644853543	264	51.56	1	254	1	255	5.0e-96	344	COG0024	Methionine aminopeptidase	255
644853544	893	59.33	23	890	2	866	0.0e+00	1116	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
644853545	274	56.07	1	273	1	271	5.0e-88	317	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
644853547	150	30.72	1	148	1	151	5.0e-25	107	COG0716	Flavodoxin	151
644853548	260	39.65	2	225	78	289	3.0e-55	208	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644853549	106	46.15	1	104	1	104	8.0e-28	115	COG3098	Uncharacterized conserved protein YqcC, DUF446 family	109
644853551	454	33.17	136	338	4	201	1.0e-44	174	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
644853552	253	38.37	4	246	12	267	1.0e-56	213	COG0258	5'-3' exonuclease	310
644853553	366	76.97	1	356	1	356	0.0e+00	597	COG2933	23S rRNA C2498 (ribose-2'-O)-methylase RlmM	358
644853554	128	54.4	2	126	1	124	2.0e-26	111	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
644853555	308	27.33	6	298	1	297	3.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
644853557	401	47.41	3	398	2	405	1.0e-117	416	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
644853558	147	47.18	5	146	1	142	1.0e-41	162	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
644853559	277	62.17	1	267	1	262	2.0e-105	375	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
644853561	337	33.64	3	330	1	323	1.0e-62	233	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
644853562	159	22.73	6	133	1	118	2.0e-06	45.6	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
644853563	170	23.39	3	163	9	179	7.0e-15	73.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644853564	387	48.53	1	361	1	369	5.0e-115	408	COG2821	Membrane-bound lytic murein transglycosylase	373
644853567	412	35.27	170	410	25	231	4.0e-51	195	COG0860	N-acetylmuramoyl-L-alanine amidase	231
644853568	441	43.01	23	290	1	264	1.0e-79	290	COG0548	Acetylglutamate kinase	265
644853569	967	50.37	21	955	2	936	0.0e+00	982	COG1025	Secreted/periplasmic Zn-dependent peptidases, insulinase-like	937
644853572	200	28.93	5	198	1	194	5.0e-22	97.8	COG4795	Type II secretory pathway, component PulJ	194
644853573	163	15.89	3	153	2	142	3.0e-09	55.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
644853574	264	68.42	1	264	3	268	8.0e-120	423	COG0207	Thymidylate synthase	268
644853575	287	48.12	1	285	1	279	2.0e-75	276	COG0682	Prolipoprotein diacylglyceryltransferase	287
644853576	749	57.41	2	749	1	756	0.0e+00	953	COG3605	Signal transduction protein containing GAF and PtsI domains	756
644853577	175	23.57	2	152	4	151	4.0e-12	64.6	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
644853578	228	76.75	1	228	1	228	2.0e-102	365	COG3066	DNA mismatch repair protein MutH	229
644853579	238	47.95	1	238	7	250	9.0e-57	213	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
644853581	346	41.83	1	346	1	316	4.0e-85	308	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
644853583	114	63.06	1	111	9	119	3.0e-38	150	COG3171	Uncharacterized conserved protein YggL, DUF469 family	119
644853584	239	52.68	17	237	1	224	2.0e-76	278	COG0220	tRNA G46 methylase TrmB	227
644853585	361	53.16	1	347	5	342	2.0e-122	432	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
644853586	90	82.95	1	88	1	88	8.0e-40	155	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
644853587	360	21.68	46	353	1	296	7.0e-37	148	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
644853588	485	48.27	14	475	1	458	0.0e+00	511	COG1113	L-asparagine transporter and related permeases	462
644853589	717	45.85	97	710	1	551	0.0e+00	668	COG1982	Arginine/lysine/ornithine decarboxylase	557
644853592	204	59.3	3	200	1	176	4.0e-56	211	COG3477	Uncharacterized membrane protein YagU, involved in acid resistance, DUF1440 family	176
644853597	175	21.35	9	172	2	174	3.0e-14	71.5	COG0563	Adenylate kinase or related kinase	178
644853598	131	43.14	15	116	9	110	6.0e-25	106	COG1733	DNA-binding transcriptional regulator, HxlR family	120
644853600	1020	29.98	10	1011	1	1007	0.0e+00	741	COG0841	Multidrug efflux pump subunit AcrB	1009
644853601	381	28.81	29	381	13	371	2.0e-25	110	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644853602	389	31.96	76	389	23	330	4.0e-38	152	COG0642	Signal transduction histidine kinase	336
644853603	231	43.16	4	231	1	228	2.0e-49	189	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644853604	261	23.81	34	261	35	258	4.0e-22	98.4	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
644853605	369	21.58	2	255	1	272	2.0e-17	83.8	COG3320	Thioester reductase domain of alpha aminoadipate reductase Lys2 and NRPSs	382
644853607	753	31.66	7	750	46	761	2.0e-130	459	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
644853608	177	62.28	1	167	4	169	1.0e-49	189	COG2862	Uncharacterized membrane protein YqhA	169
644853610	248	42.34	6	247	9	249	8.0e-42	163	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644853612	289	26.24	81	280	25	224	9.0e-25	107	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
644853613	280	60.5	12	130	14	132	2.0e-43	169	COG2904	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, N-terminal domain	137
644853614	311	27.76	3	295	2	293	3.0e-31	129	COG0583	DNA-binding transcriptional regulator, LysR family	297
644853615	361	46.07	6	361	4	347	3.0e-124	438	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
644853617	397	25.82	5	397	12	393	3.0e-20	93.3	COG2814	Predicted arabinose efflux permease, MFS family	394
644853618	431	27.36	20	431	2	431	2.0e-35	144	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
644853619	290	44.29	1	288	4	292	8.0e-65	240	COG1175	ABC-type sugar transport system, permease component	295
644853620	275	43.43	4	273	7	278	1.0e-48	186	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
644853621	368	50.86	1	349	1	338	2.0e-122	432	COG3839	ABC-type sugar transport system, ATPase component	338
644853622	255	20.36	1	231	2	276	4.0e-16	78.6	COG1234	Ribonuclease BN, tRNA processing enzyme	292
644853623	328	34.65	6	328	1	326	1.0e-60	226	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644853624	300	24.91	2	291	1	287	1.0e-28	120	COG0583	DNA-binding transcriptional regulator, LysR family	297
644853625	324	27.9	54	323	54	312	2.0e-27	116	COG0657	Acetyl esterase/lipase	312
644853626	232	39.9	33	228	1	197	1.0e-51	196	COG0437	Fe-S-cluster-containing dehydrogenase component	203
644853627	318	43.71	4	318	6	305	7.0e-50	191	COG3301	Formate-dependent nitrite reductase, membrane component NrfD	305
644853628	457	22.19	4	367	12	381	6.0e-12	66	COG2814	Predicted arabinose efflux permease, MFS family	394
644853630	523	23.05	44	518	1	412	3.0e-26	113	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
644853631	217	47	5	203	4	190	2.0e-45	175	COG3145	Alkylated DNA repair dioxygenase AlkB	194
644853632	329	28.53	3	314	2	303	5.0e-17	81.9	COG3547	Transposase	303
644853633	224	40.65	13	217	68	280	5.0e-45	174	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
644853634	154	49.26	13	148	6	141	3.0e-41	160	COG4125	Uncharacterized membrane protein	149
644853635	288	26.21	6	286	4	290	6.0e-29	121	COG0583	DNA-binding transcriptional regulator, LysR family	297
644853636	547	43.83	38	344	1	297	7.0e-100	358	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
644853637	508	52.12	3	508	27	546	0.0e+00	556	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
644853638	494	43.22	5	394	7	388	5.0e-129	455	COG0426	Flavorubredoxin	388
644853640	287	54.74	1	95	5	99	4.0e-32	132	COG3615	Uncharacterized protein/domain, possibly involved in tellurite resistance	99
644853641	217	60.29	11	214	1	203	4.0e-80	290	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
644853642	94	47.87	1	94	10	103	7.0e-20	88.5	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
644853643	417	24.13	1	407	4	433	1.0e-24	107	COG0531	Amino acid transporter	466
644853644	308	51.23	2	303	1	323	7.0e-79	287	COG3115	Cell division protein ZipA, interacts with FtsZ	324
644853645	256	62.71	12	247	7	242	5.0e-79	287	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
644853646	322	61.81	4	308	1	300	7.0e-111	393	COG0031	Cysteine synthase	300
644853647	85	51.19	1	84	1	84	7.0e-25	105	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
644853648	575	63.35	1	573	2	574	0.0e+00	812	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
644853649	169	55.13	16	169	1	156	4.0e-48	184	COG2190	Phosphotransferase system IIA component	156
644853650	186	41.75	1	102	1	103	8.0e-21	93.5	COG1733	DNA-binding transcriptional regulator, HxlR family	120
644853651	321	31.37	64	318	7	257	3.0e-40	159	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
644853652	465	27.51	132	465	3	331	4.0e-42	166	COG0642	Signal transduction histidine kinase	336
644853653	232	44.74	7	232	1	226	2.0e-59	222	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644853654	293	49.16	3	289	4	300	2.0e-101	362	COG0031	Cysteine synthase	300
644853655	299	41.61	1	299	22	343	1.0e-83	303	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
644853656	431	27.18	12	416	14	409	4.0e-33	136	COG1457	Purine-cytosine permease or related protein	442
644853659	95	70.37	1	81	1	81	6.0e-25	105	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
644853660	424	26.34	1	420	1	395	4.0e-40	159	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
644853662	553	40.78	2	549	23	586	0.0e+00	512	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
644853663	913	25.68	6	441	1	422	1.0e-44	175	COG0612	Predicted Zn-dependent peptidase	438
644853665	194	26.15	1	188	49	243	1.0e-15	76.3	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
644853666	141	33.33	1	123	12	149	6.0e-12	63.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
644853667	312	68.32	1	302	2	303	0.0e+00	485	COG0408	Coproporphyrinogen III oxidase	303
644853668	150	54.36	1	149	1	147	7.0e-50	189	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
644853669	759	57.47	1	433	13	432	0.0e+00	603	COG0281	Malic enzyme	432
644853670	194	22.62	36	190	2	160	5.0e-06	44.6	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
644853671	411	44.77	8	411	6	414	2.0e-86	313	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
644853672	195	43.01	2	194	5	193	3.0e-39	155	COG0576	Molecular chaperone GrpE (heat shock protein)	193
644853673	292	47.55	6	289	1	281	9.0e-79	287	COG0061	NAD kinase	281
644853674	553	50.99	1	553	1	554	0.0e+00	631	COG0497	DNA repair ATPase RecN	557
644853675	114	42.02	1	114	4	121	2.0e-27	114	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
644853676	97	66.67	1	96	1	96	1.0e-31	128	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
644853677	144	59.44	1	142	1	143	2.0e-55	207	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
644853678	160	61.44	8	160	2	153	1.0e-56	212	COG0691	tmRNA-binding protein	153
644853682	305	31.23	10	293	1	298	7.0e-34	137	COG3866	Pectate lyase	345
644853685	303	20	7	300	5	323	5.0e-10	58.8	COG3156	Type II secretory pathway, component PulK	323
644853686	181	21.76	2	179	3	191	2.0e-11	62.3	COG4795	Type II secretory pathway, component PulJ	194
644853688	138	32.87	10	136	7	149	2.0e-15	75.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
644853689	401	39.9	1	401	1	396	1.0e-79	290	COG1459	Type II secretory pathway, component PulF	397
644853690	491	48.45	8	487	22	500	0.0e+00	506	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
644853691	696	25.39	33	673	23	580	2.0e-74	273	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
644853693	469	29.77	27	416	13	402	4.0e-43	169	COG0534	Na+-driven multidrug efflux pump	455
644853694	492	37.85	13	477	1	448	2.0e-54	206	COG1538	Outer membrane protein TolC	457
644853695	205	22.61	8	203	2	200	1.0e-08	53.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644853696	371	28.03	1	362	5	372	2.0e-18	86.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644853697	1021	28.27	7	1015	1	1009	0.0e+00	807	COG0841	Multidrug efflux pump subunit AcrB	1009
644853698	268	29.2	1	265	3	260	2.0e-43	169	COG0300	Short-chain dehydrogenase	265
644853699	428	51.18	5	426	1	412	3.0e-123	435	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644853700	273	40.44	3	184	7	189	2.0e-39	156	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
644853701	128	41.12	21	127	13	119	3.0e-25	107	COG1733	DNA-binding transcriptional regulator, HxlR family	120
644853703	211	27.23	1	204	1	205	2.0e-16	79.2	COG2910	Putative NADH-flavin reductase	211
644853704	260	24.63	1	259	3	271	2.0e-32	133	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644853706	381	37.97	43	380	9	341	1.0e-75	277	COG2951	Membrane-bound lytic murein transglycosylase B	343
644853707	329	28.53	3	314	2	303	5.0e-17	81.9	COG3547	Transposase	303
644853708	275	58.52	1	269	1	269	2.0e-110	392	COG3718	5-deoxy-D-glucuronate isomerase	270
644853709	296	31.65	5	291	1	273	2.0e-41	163	COG1082	Sugar phosphate isomerase/epimerase	274
644853710	647	55.45	339	647	6	303	7.0e-121	428	COG3892	Myo-inositol catabolism protein IolC	310
644853711	377	31.02	1	373	1	340	2.0e-53	203	COG0673	Predicted dehydrogenase	342
644853712	346	48.14	25	345	5	315	1.0e-65	243	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
644853713	521	48.23	6	512	3	498	0.0e+00	612	COG1129	ABC-type sugar transport system, ATPase component	500
644853714	312	33.87	7	311	16	322	1.0e-46	180	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
644853715	328	31.96	1	328	3	340	2.0e-52	199	COG0673	Predicted dehydrogenase	342
644853716	249	51.24	5	245	2	233	1.0e-78	286	COG3910	Predicted ATPase	233
644853718	643	54.43	1	643	2	617	0.0e+00	872	COG3962	TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism	617
644853719	503	39.79	4	486	1	471	7.0e-120	424	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644853720	285	34.75	8	285	3	275	8.0e-50	190	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
644853721	366	42.21	2	351	1	317	1.0e-93	336	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
644853722	94	24.73	1	91	3	91	5.0e-14	69.5	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
644853726	477	38.66	6	463	8	462	2.0e-107	383	COG2211	Na+/melibiose symporter or related transporter	467
644853727	522	27.07	13	514	15	542	1.0e-52	201	COG3507	Beta-xylosidase	549
644853729	181	31.46	2	173	1	177	3.0e-25	108	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644853731	1177	40.16	1	383	3	361	9.0e-98	352	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
644853732	358	35.42	3	237	2	232	4.0e-36	145	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
644853733	244	27.12	37	208	11	186	2.0e-17	83.1	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644853734	151	30.65	20	142	4	126	1.0e-09	55.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
644853735	373	30.75	15	373	10	340	1.0e-49	190	COG1566	Multidrug resistance efflux pump	352
644853737	498	49.58	19	495	1	473	0.0e+00	544	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
644853738	106	62.32	34	102	1	69	1.0e-20	91.5	COG3655	DNA-binding transcriptional regulator, XRE family	73
644853739	508	28.03	1	471	5	466	6.0e-84	305	COG2211	Na+/melibiose symporter or related transporter	467
644853740	336	20.94	1	332	8	339	2.0e-08	53.8	COG0628	Predicted PurR-regulated permease PerM	355
644853741	268	50.6	12	261	3	252	4.0e-84	304	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
644853742	297	50.75	23	286	1	268	4.0e-93	334	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
644853743	301	53.28	30	301	14	287	6.0e-73	267	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644853744	352	45.07	18	352	1	315	4.0e-84	305	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644853745	536	26.81	1	534	6	552	8.0e-68	251	COG0747	ABC-type transport system, periplasmic component	556
644853746	384	31.52	1	382	1	369	1.0e-59	223	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644853749	653	44.6	68	631	1	528	0.0e+00	673	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
644853750	103	64.08	1	103	1	102	6.0e-32	128	COG3162	Uncharacterized membrane protein, DUF485 family	102
644853751	552	58.91	30	544	1	529	0.0e+00	561	COG4147	Na+(or H+)/acetate symporter ActP	529
644853752	548	37.95	1	440	6	422	1.0e-70	261	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
644853753	455	45.58	14	453	2	436	9.0e-105	374	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
644853754	306	50	6	306	6	308	4.0e-91	328	COG1560	Lauroyl/myristoyl acyltransferase	308
644853755	142	38.46	76	140	4	68	7.0e-10	56.5	COG3585	Molybdopterin-binding protein	69
644853756	290	38.62	1	290	6	295	1.0e-53	203	COG1175	ABC-type sugar transport system, permease component	295
644853757	295	36.46	24	295	7	281	2.0e-48	186	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
644853758	273	27.13	1	234	1	236	2.0e-23	103	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
644853759	361	50.86	1	349	1	338	7.0e-115	407	COG3839	ABC-type sugar transport system, ATPase component	338
644853760	440	28.38	1	430	1	433	1.0e-38	154	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
644853761	182	46.02	3	173	42	217	4.0e-46	177	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
644853762	324	31.38	1	312	1	311	2.0e-39	156	COG0451	Nucleoside-diphosphate-sugar epimerase	314
644853763	630	41.9	19	626	1	585	0.0e+00	618	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
644853764	94	32.99	1	93	3	98	2.0e-07	47.5	COG2963	Transposase and inactivated derivatives	116
644853765	125	43.52	10	117	10	117	6.0e-28	116	COG1733	DNA-binding transcriptional regulator, HxlR family	120
644853766	327	21.85	46	278	6	225	3.0e-08	52.7	COG2801	Transposase InsO and inactivated derivatives	232
644853768	338	47.63	1	336	1	329	1.0e-126	446	COG1087	UDP-glucose 4-epimerase	329
644853769	377	26.45	1	120	1	121	6.0e-23	101	COG5433	Predicted transposase YbfD/YdcC associated with H repeats	121
644853770	381	23.03	27	378	33	380	2.0e-29	123	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644853772	377	27.27	1	120	1	121	5.0e-23	102	COG5433	Predicted transposase YbfD/YdcC associated with H repeats	121
644853776	376	15.18	1	356	1	344	4.0e-12	66.1	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644853777	339	17.01	13	292	5	289	2.0e-06	47.1	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
644853780	275	20.64	1	268	1	270	8.0e-12	64.5	COG1082	Sugar phosphate isomerase/epimerase	274
644853787	331	21.85	50	282	6	225	4.0e-08	52.7	COG2801	Transposase InsO and inactivated derivatives	232
644853790	322	25.56	9	318	3	296	2.0e-16	80.3	COG3547	Transposase	303
644853792	223	24.54	1	214	2	207	7.0e-10	57.6	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644853793	505	64	9	505	4	502	0.0e+00	759	COG1190	Lysyl-tRNA synthetase (class II)	502
644853794	365	65.69	128	365	1	239	1.0e-101	363	COG1186	Protein chain release factor B	239
644853795	576	43.65	38	553	4	491	8.0e-119	421	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
644853796	238	26.34	1	232	4	244	2.0e-35	143	COG1651	Protein-disulfide isomerase	244
644853797	299	63.79	1	299	1	300	1.0e-118	419	COG4974	Site-specific recombinase XerD	300
644853798	441	20.05	72	432	71	433	1.0e-09	58.3	COG2271	Sugar phosphate permease	448
644853799	172	33.53	1	168	2	151	5.0e-29	120	COG0716	Flavodoxin	151
644853801	90	52.94	3	87	10	94	4.0e-25	106	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
644853802	326	39.51	5	326	1	305	1.0e-69	257	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
644853803	216	59.81	10	215	16	223	5.0e-50	191	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
644853804	202	28.28	13	153	2	145	7.0e-13	67.3	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
644853805	218	44.86	4	217	2	208	2.0e-29	123	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644853806	957	57.65	8	446	1	450	0.0e+00	604	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
644853806	957	65.02	457	928	16	493	0.0e+00	742	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
644853807	135	58.46	1	129	2	131	5.0e-41	159	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
644853808	366	46.58	1	362	4	375	5.0e-105	374	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
644853809	383	45.05	2	383	1	377	3.0e-112	398	COG1454	Alcohol dehydrogenase, class IV	377
644853810	559	36.83	12	550	3	539	7.0e-130	457	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
644853811	262	41.88	28	261	1	234	2.0e-69	255	COG3527	Alpha-acetolactate decarboxylase	234
644853812	297	34.16	1	279	1	275	5.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
644853817	300	32.78	5	298	4	295	6.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
644853818	331	41.3	1	318	1	316	1.0e-88	320	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
644853819	342	48.66	40	335	1	298	6.0e-92	331	COG2813	16S rRNA G1207 methylase RsmC	300
644853820	137	57.14	2	133	1	133	3.0e-36	143	COG3050	DNA polymerase III, psi subunit	133
644853821	147	27.88	1	146	11	173	4.0e-17	80.4	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
644853823	241	73.73	1	236	1	236	3.0e-112	398	COG0813	Purine-nucleoside phosphorylase	236
644853824	407	64.36	1	404	1	390	0.0e+00	609	COG1015	Phosphopentomutase	397
644853825	443	51.83	1	438	1	434	0.0e+00	541	COG0213	Thymidine phosphorylase	435
644853826	259	38.25	4	254	1	227	1.0e-55	209	COG0274	Deoxyribose-phosphate aldolase	228
644853827	100	46.67	8	97	5	94	4.0e-24	102	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
644853828	167	50.3	1	167	4	171	6.0e-41	160	COG3153	Predicted N-acetyltransferase YhbS	171
644853829	174	55.56	6	167	1	161	1.0e-45	175	COG3154	Predicted lipid carrier protein YhbT, SCP2 domain	168
644853830	332	37.09	1	332	7	312	9.0e-82	297	COG0826	Collagenase-like protease, PrtC family	347
644853831	292	24.44	2	292	1	304	2.0e-53	203	COG0826	Collagenase-like protease, PrtC family	347
644853832	339	26.04	15	333	2	336	4.0e-43	168	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
644853833	624	42.74	3	479	26	508	7.0e-125	441	COG0513	Superfamily II DNA and RNA helicase	513
644853834	294	79.8	1	294	1	297	2.0e-127	448	COG4785	Lipoprotein NlpI, contains TPR repeats	297
644853835	706	66.18	1	692	1	690	0.0e+00	1033	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
644853836	89	61.8	1	89	1	89	4.0e-28	116	COG0184	Ribosomal protein S15P/S13E	89
644853837	318	38.59	1	311	4	271	1.0e-71	263	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
644853838	133	50	1	120	1	118	3.0e-31	127	COG0858	Ribosome-binding factor A	118
644853839	905	67.13	402	905	1	508	0.0e+00	698	COG0532	Translation initiation factor IF-2, a GTPase	509
644853840	496	51.53	157	351	1	190	3.0e-51	196	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
644853841	154	58	6	154	4	153	3.0e-51	193	COG0779	Ribosome maturation factor RimP	153
644853844	111	49.44	1	89	1	85	2.0e-16	77.9	COG1314	Preprotein translocase subunit SecG	86
644853845	445	45.97	1	444	4	460	2.0e-123	436	COG1109	Phosphomannomutase	464
644853846	277	48.87	15	277	8	269	4.0e-81	294	COG0294	Dihydropteroate synthase	274
644853847	650	62.06	9	604	1	596	0.0e+00	804	COG0465	ATP-dependent Zn proteases	596
644853848	209	59.9	7	208	1	202	1.0e-76	279	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
644853849	97	59.79	2	97	1	97	6.0e-27	112	COG1534	RNA-binding protein YhbY	97
644853850	158	55.92	6	157	1	150	9.0e-46	176	COG0782	Transcription elongation factor, GreA/GreB family	151
644853851	477	44.77	1	476	1	470	0.0e+00	482	COG2027	D-alanyl-D-alanine carboxypeptidase	470
644853852	391	62.16	1	368	1	368	0.0e+00	545	COG0536	GTPase involved in cell partioning and DNA repair	369
644853854	85	81.18	1	85	1	84	6.0e-32	128	COG0211	Ribosomal protein L27	87
644853855	103	62.14	1	103	1	103	2.0e-34	137	COG0261	Ribosomal protein L21	103
644853856	323	38.53	4	323	1	322	1.0e-80	293	COG0142	Geranylgeranyl pyrophosphate synthase	322
644853859	313	36.11	1	312	1	313	3.0e-67	248	COG0039	Malate/lactate dehydrogenase	313
644853860	156	51.33	6	152	3	150	3.0e-42	164	COG1438	Arginine repressor	150
644853861	337	57.02	1	337	1	340	0.0e+00	464	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
644853862	71	61.19	1	67	1	67	2.0e-06	44.5	COG0828	Ribosomal protein S21	67
644853863	584	42.51	4	573	1	556	0.0e+00	512	COG0358	DNA primase (bacterial type)	568
644853864	611	50.7	254	610	1	342	7.0e-101	361	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
644853866	287	45.31	1	238	1	243	1.0e-58	219	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
644853867	287	38.13	7	259	9	265	4.0e-60	224	COG0300	Short-chain dehydrogenase	265
644853868	349	39.06	1	316	1	309	2.0e-70	259	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
644853869	193	19.37	1	191	2	191	7.0e-09	53.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644853870	323	35.65	1	315	24	337	2.0e-72	266	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
644853871	925	36.34	5	364	4	362	1.0e-82	301	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
644853872	475	33.57	32	445	55	466	1.0e-79	291	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644853873	349	43.04	34	345	26	336	5.0e-91	328	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
644853874	423	37.23	26	290	55	328	5.0e-50	192	COG3344	Retron-type reverse transcriptase	328
644853876	158	40.4	1	151	2	149	8.0e-20	90	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
644853877	463	44.42	2	455	1	445	4.0e-126	445	COG2271	Sugar phosphate permease	448
644853878	447	51.25	8	442	3	441	0.0e+00	515	COG2271	Sugar phosphate permease	448
644853879	505	66.6	7	498	3	493	0.0e+00	604	COG3851	Signal transduction histidine kinase, glucose-6-phosphate specific	497
644853880	196	44.88	2	194	1	205	3.0e-48	184	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644853882	385	35.9	72	383	2	300	4.0e-84	305	COG2813	16S rRNA G1207 methylase RsmC	300
644853883	317	30.49	77	317	18	250	5.0e-39	155	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
644853885	496	53.54	103	496	1	381	0.0e+00	536	COG2721	Altronate dehydratase	381
644853886	483	32.72	4	482	3	473	5.0e-113	401	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
644853887	469	59.14	3	467	1	463	0.0e+00	683	COG1904	Glucuronate isomerase	463
644853888	433	25.94	5	413	24	435	1.0e-29	124	COG2271	Sugar phosphate permease	448
644853889	259	33.19	1	233	3	238	8.0e-48	184	COG2186	DNA-binding transcriptional regulator, FadR family	241
644853890	224	33.85	26	216	14	205	1.0e-32	133	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
644853892	101	56.38	8	101	11	104	3.0e-24	103	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
644853893	132	57.25	1	131	1	131	4.0e-24	103	COG5393	Uncharacterized membrane protein YqjE	131
644853895	131	39.23	5	131	12	141	2.0e-14	71.2	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
644853896	328	69.63	1	326	1	323	0.0e+00	526	COG0435	Glutathionyl-hydroquinone reductase	324
644853897	298	24.57	7	295	1	291	1.0e-24	107	COG0583	DNA-binding transcriptional regulator, LysR family	297
644853898	235	33.33	1	233	1	242	1.0e-41	163	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
644853899	169	31.72	8	152	3	145	7.0e-33	133	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
644853900	203	49.75	1	199	1	199	7.0e-58	216	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
644853901	121	56.67	1	120	2	121	2.0e-33	134	COG0818	Diacylglycerol kinase	123
644853902	825	65.85	1	809	1	809	0.0e+00	1080	COG2937	Glycerol-3-phosphate O-acyltransferase	810
644853903	294	42.86	16	294	9	288	9.0e-56	210	COG0382	4-hydroxybenzoate polyprenyltransferase	289
644853904	171	32.56	9	166	2	173	8.0e-26	110	COG3161	4-hydroxybenzoate synthetase (chorismate-pyruvate lyase)	174
644853905	548	49.27	1	530	1	520	0.0e+00	496	COG0459	Chaperonin GroEL (HSP60 family)	524
644853906	97	64.95	1	97	1	96	2.0e-28	117	COG0234	Co-chaperonin GroES (HSP10)	96
644853907	166	44.3	1	155	1	158	3.0e-37	147	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
644853908	479	73.83	4	473	3	471	0.0e+00	796	COG1027	Aspartate ammonia-lyase	471
644853909	433	61.01	1	433	1	436	0.0e+00	514	COG2704	Anaerobic C4-dicarboxylate transporter	436
644853910	126	44.23	23	126	1	104	5.0e-33	133	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
644853911	572	49.91	6	572	1	569	0.0e+00	587	COG4232	Thiol:disulfide interchange protein	569
644853912	191	23.49	3	167	14	179	8.0e-06	43.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644853914	419	16.29	98	400	22	309	1.0e-08	55	COG0582	Integrase	309
644853918	72	33.33	7	72	15	80	1.0e-11	61.6	COG5302	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid	80
644853920	280	19.6	6	248	5	239	1.0e-17	84.2	COG0338	Site-specific DNA-adenine methylase	274
644853921	573	17.43	8	321	2	348	1.0e-08	55.5	COG1106	ATPase/GTPase, AAA15 family	371
644853923	97	49.47	2	96	1	95	8.0e-19	85.4	COG4453	Uncharacterized conserved protein, DUF1778 family	95
644853927	370	23.12	4	365	1	377	4.0e-30	125	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644853928	403	23.88	1	403	1	381	4.0e-33	135	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644853929	329	22.26	6	312	55	372	9.0e-15	74.6	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
644853932	710	23.08	7	453	3	456	1.0e-39	158	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
644853933	185	31.75	5	185	19	201	5.0e-25	107	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
644853935	468	43.97	238	468	1	226	4.0e-67	249	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
644853936	396	39.89	42	386	11	364	3.0e-74	272	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644853937	340	34.45	17	339	1	328	1.0e-73	270	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644853938	143	36.84	1	113	1	114	1.0e-20	92.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
644853939	785	41.7	79	776	2	712	0.0e+00	671	COG2217	Cation transport ATPase	713
644853940	384	26.32	1	333	3	336	2.0e-34	139	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
644853941	322	33.85	6	255	8	261	1.0e-41	163	COG1018	Ferredoxin-NADP reductase	266
644853942	344	22.58	1	337	1	356	1.0e-26	114	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
644853943	312	23.99	9	302	7	297	2.0e-23	103	COG0583	DNA-binding transcriptional regulator, LysR family	297
644853944	166	31.58	1	166	5	173	2.0e-13	68.4	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
644853945	110	35.9	1	110	8	124	4.0e-22	96.5	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
644853946	220	33.13	13	173	20	181	1.0e-24	106	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
644853947	274	40	40	264	21	239	1.0e-57	216	COG5255	Uncharacterized protein	239
644853948	520	71.92	1	520	1	519	0.0e+00	839	COG3634	Alkyl hydroperoxide reductase subunit AhpF	520
644853949	187	48.94	1	184	2	188	2.0e-62	231	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
644853950	332	44.88	5	332	2	329	9.0e-52	197	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
644853951	330	23.42	1	327	1	315	7.0e-33	134	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
644853952	271	40	7	255	1	254	3.0e-58	218	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
644853955	572	36.12	149	530	2	408	6.0e-51	195	COG0840	Methyl-accepting chemotaxis protein	408
644853956	250	52.34	1	233	1	233	7.0e-73	267	COG3967	Short-chain dehydrogenase involved in D-alanine esterification of teichoic acids	245
644853957	239	35.81	23	236	14	225	4.0e-42	164	COG2977	4'-phosphopantetheinyl transferase EntD (siderophore biosynthesis)	228
644853958	290	40.32	30	281	3	254	3.0e-75	275	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
644853960	218	31.68	17	217	5	195	1.0e-26	113	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
644853961	529	74.76	3	529	2	528	0.0e+00	936	COG4108	Peptide chain release factor RF-3	528
644853962	226	61.24	1	208	1	208	7.0e-64	237	COG3726	Uncharacterized membrane protein affecting hemolysin expression	214
644853963	325	50.24	108	317	2	212	1.0e-57	216	COG0560	Phosphoserine phosphatase	212
644853964	461	62.47	1	461	1	456	0.0e+00	686	COG1066	Predicted ATP-dependent serine protease	456
644853965	418	74.73	225	410	2	186	2.0e-77	283	COG3172	Nicotinamide riboside kinase	187
644853966	204	40	17	204	5	190	9.0e-45	173	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
644853967	109	43.81	3	107	1	105	8.0e-21	91.9	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
644853968	196	62.5	5	196	1	186	1.0e-65	242	COG3079	Uncharacterized conserved protein YgfB, UPF0149 family	186
644853969	442	33.01	11	420	1	374	1.0e-76	280	COG0006	Xaa-Pro aminopeptidase	384
644853970	392	37.06	1	390	3	386	5.0e-74	271	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
644853971	403	37.97	2	392	1	385	3.0e-77	282	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
644853977	542	28.11	9	542	6	554	1.0e-71	264	COG0747	ABC-type transport system, periplasmic component	556
644853978	321	39.23	14	313	6	314	1.0e-64	240	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644853979	303	44.96	22	298	5	282	1.0e-56	213	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644853980	566	48.01	6	552	2	533	0.0e+00	577	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
644853982	278	40.59	174	274	22	122	1.0e-20	93.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644853983	490	27.85	1	468	1	485	3.0e-84	306	COG1070	Sugar (pentulose or hexulose) kinase	502
644853984	418	81.1	1	418	1	418	0.0e+00	715	COG4806	L-rhamnose isomerase	419
644853985	276	25.66	2	264	1	214	2.0e-34	139	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
644853986	104	57.14	1	104	1	105	4.0e-35	139	COG3254	L-rhamnose mutarotase	105
644853987	530	34.99	164	520	26	408	9.0e-40	158	COG0840	Methyl-accepting chemotaxis protein	408
644853988	268	40.89	15	261	1	244	2.0e-52	199	COG1414	DNA-binding transcriptional regulator, IclR family	246
644853989	236	28.85	12	216	22	222	1.0e-26	113	COG1418	HD superfamily phosphodieaserase, includes HD domain of RNase Y	222
644853991	486	39.92	5	486	1	488	3.0e-88	319	COG0168	Trk-type K+ transport system, membrane component	499
644853992	176	34.62	23	99	23	100	1.0e-10	60	COG1605	Chorismate mutase	101
644853993	174	40.27	24	172	5	152	3.0e-30	125	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644853996	363	28.99	8	348	1	371	3.0e-74	272	COG4637	Predicted ATPase	373
644853997	338	54.33	1	335	1	323	3.0e-118	418	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
644853998	310	28.81	1	300	1	297	9.0e-31	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
644853999	472	22.66	6	458	1	409	1.0e-27	117	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644854001	324	56.15	1	314	1	312	3.0e-119	421	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
644854002	308	49.46	26	301	10	281	2.0e-65	243	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644854003	305	46.82	1	303	1	314	2.0e-82	299	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644854004	514	26.43	6	514	1	553	1.0e-69	257	COG0747	ABC-type transport system, periplasmic component	556
644854009	265	40.38	4	262	2	250	7.0e-53	200	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644854010	503	41.6	1	496	2	494	0.0e+00	505	COG0554	Glycerol kinase	499
644854011	355	44.38	7	334	4	316	1.0e-58	220	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
644854012	532	45.47	28	531	1	500	0.0e+00	551	COG1129	ABC-type sugar transport system, ATPase component	500
644854013	207	28.37	5	205	15	206	1.0e-17	83.6	COG5618	Predicted periplasmic lipoprotein	206
644854014	311	33.44	1	310	9	321	6.0e-45	174	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
644854015	267	34.9	19	265	1	251	5.0e-43	168	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644854016	307	35.76	1	294	5	304	1.0e-72	267	COG3958	Transketolase, C-terminal subunit	312
644854017	267	48.55	1	236	5	243	4.0e-73	268	COG3959	Transketolase, N-terminal subunit	243
644854018	263	39.13	11	263	3	253	3.0e-56	212	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
644854019	386	29.84	1	374	2	373	8.0e-41	161	COG4637	Predicted ATPase	373
644854023	207	42	3	202	2	200	1.0e-45	176	COG1279	Arginine exporter protein ArgO	202
644854027	411	24.78	1	339	2	325	4.0e-34	139	COG0644	Dehydrogenase (flavoprotein)	396
644854028	439	35.35	12	419	24	447	3.0e-108	385	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
644854029	446	31.38	14	436	3	411	3.0e-92	332	COG3486	Lysine/ornithine N-monooxygenase	436
644854031	133	35.14	13	121	1	110	1.0e-16	78.8	COG0607	Rhodanese-related sulfurtransferase	110
644854032	294	29.43	4	288	18	309	1.0e-25	110	COG0657	Acetyl esterase/lipase	312
644854033	310	18.44	28	298	43	356	1.0e-07	50.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
644854034	352	24.03	10	348	6	365	6.0e-29	121	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644854038	157	19.72	1	137	10	148	3.0e-09	54.6	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
644854043	436	30.08	28	414	32	419	2.0e-71	263	COG4268	5-methylcytosine-specific restriction endonuclease McrBC, regulatory subunit McrC	439
644854045	1174	26.38	251	1171	2	873	2.0e-130	460	COG4096	Type I site-specific restriction endonuclease, part of a restriction-modification system	875
644854046	533	25.62	1	496	2	487	3.0e-63	236	COG0286	Type I restriction-modification system, DNA methylase subunit	489
644854047	459	21.87	10	412	1	391	4.0e-23	102	COG0732	Restriction endonuclease S subunit	391
644854050	282	39.92	20	280	25	276	5.0e-55	208	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
644854051	285	26.72	36	280	37	278	7.0e-12	64.9	COG5006	Threonine/homoserine efflux transporter RhtA	292
644854053	306	23.1	7	296	1	288	4.0e-23	102	COG0583	DNA-binding transcriptional regulator, LysR family	297
644854054	134	38.35	1	132	1	131	1.0e-27	115	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
644854055	76	50	4	76	3	74	3.0e-16	76.9	COG4456	Virulence-associated protein VagC (function unknown)	74
644854056	357	22.35	3	332	8	283	9.0e-23	101	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
644854063	290	30.54	1	289	5	301	2.0e-58	219	COG3440	Predicted restriction endonuclease	301
644854066	107	61.17	4	106	1	103	3.0e-32	130	COG2944	DNA-binding transcriptional regulator YiaG, XRE-type HTH domain	104
644854067	119	56.1	1	117	1	123	8.0e-37	145	COG4737	Uncharacterized protein	123
644854068	67	57.14	1	63	7	69	3.0e-15	73.4	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
644854070	678	41.69	1	312	1	314	3.0e-66	246	COG4643	Uncharacterized domain associated with phage/plasmid primase	366
644854071	444	30.83	41	420	6	384	8.0e-58	218	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
644854073	418	20.86	84	403	1	309	4.0e-09	56.5	COG0582	Integrase	309
644854074	83	46.34	2	83	12	93	6.0e-18	82.3	COG4453	Uncharacterized conserved protein, DUF1778 family	95
644854076	88	75.38	6	70	7	71	1.0e-22	98.2	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
644854077	681	40.88	1	333	1	333	3.0e-69	256	COG4643	Uncharacterized domain associated with phage/plasmid primase	366
644854079	67	57.14	1	63	7	69	3.0e-15	73.4	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
644854084	281	21.32	5	275	4	257	1.0e-26	114	COG1192	Cellulose biosynthesis protein BcsQ	259
644854086	419	18.58	85	402	1	309	2.0e-07	50.3	COG0582	Integrase	309
644854088	356	35.08	2	356	1	362	4.0e-62	232	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
644854089	370	36.91	1	352	2	364	3.0e-60	225	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
644854090	502	51.9	1	497	1	485	0.0e+00	592	COG0260	Leucyl aminopeptidase	485
644854091	149	51.33	1	148	1	143	1.0e-38	152	COG2927	DNA polymerase III, chi subunit	144
644854092	951	55.19	1	950	1	877	0.0e+00	1243	COG0525	Valyl-tRNA synthetase	877
644854093	539	36.1	167	515	35	408	7.0e-50	192	COG0840	Methyl-accepting chemotaxis protein	408
644854094	355	26.63	20	348	6	366	1.0e-43	170	COG2021	Homoserine acetyltransferase	368
644854096	195	30.25	18	127	2	120	5.0e-07	48.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
644854097	167	20.75	1	151	2	160	2.0e-09	55.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644854098	475	23.2	313	460	30	207	1.0e-06	48.4	COG4735	Uncharacterized protein YaaW, UPF0174 family	211
644854100	142	76.98	4	142	1	135	2.0e-38	151	COG3076	Regulator of RNase E activity RraB	135
644854101	338	52.55	1	333	1	310	0.0e+00	464	COG0078	Ornithine carbamoyltransferase	310
644854102	478	47.7	1	477	1	456	0.0e+00	567	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
644854103	155	41.18	1	153	1	153	2.0e-46	178	COG2731	Beta-galactosidase, beta subunit	154
644854104	311	54.57	1	308	1	314	6.0e-114	404	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
644854105	154	59.48	1	152	1	152	1.0e-54	205	COG1781	Aspartate carbamoyltransferase, regulatory subunit	153
644854106	128	50.39	1	128	3	129	5.0e-33	133	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
644854108	446	29.29	1	445	3	468	2.0e-69	256	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
644854109	563	21	37	542	1	445	2.0e-21	97.7	COG1231	Monoamine oxidase	450
644854111	531	44.12	1	521	2	539	0.0e+00	540	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
644854112	271	39.53	5	259	21	278	5.0e-53	201	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644854113	314	41.4	2	313	4	317	4.0e-70	258	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644854114	513	27.11	1	512	6	556	5.0e-71	262	COG0747	ABC-type transport system, periplasmic component	556
644854115	302	31.07	3	300	8	298	2.0e-46	179	COG2040	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)	300
644854116	712	44.55	1	706	1	699	0.0e+00	888	COG1328	Anaerobic ribonucleoside-triphosphate reductase	700
644854117	154	34.34	1	154	2	167	3.0e-30	124	COG0602	Organic radical activating enzyme	212
644854118	150	56.64	6	148	1	143	2.0e-51	194	COG3787	Uncharacterized conserved protein YhbP, UPF0306 family	145
644854122	307	35.42	4	305	1	305	8.0e-54	204	COG0524	Sugar or nucleoside kinase, ribokinase family	311
644854123	538	24.77	111	538	18	429	3.0e-31	130	COG4580	Maltoporin (phage lambda and maltose receptor)	429
644854124	456	32.27	95	452	1	375	6.0e-66	245	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
644854125	470	46.5	24	447	26	463	4.0e-130	458	COG1621	Sucrose-6-phosphate hydrolase SacC, GH32 family	486
644854126	339	36.23	7	338	1	331	7.0e-67	247	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644854127	139	44.44	3	137	1	135	8.0e-36	142	COG0848	Biopolymer transport protein ExbD	137
644854128	296	44.39	67	277	1	214	9.0e-45	174	COG0811	Biopolymer transport protein ExbB/TolQ	216
644854129	397	37.78	4	395	6	396	3.0e-117	415	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
644854130	219	34.87	26	219	14	208	1.0e-31	130	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
644854131	304	40	180	299	8	127	2.0e-23	103	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644854132	387	65.37	1	387	1	384	0.0e+00	599	COG1979	Alcohol dehydrogenase YqhD, Fe-dependent ADH family	384
644854133	281	48.38	2	271	1	276	4.0e-96	344	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
644854134	470	39.75	5	470	1	450	1.0e-82	300	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
644854135	245	29.17	5	238	1	236	1.0e-33	136	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
644854136	758	42.62	1	758	1	755	0.0e+00	799	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
644854137	193	34.33	3	193	2	189	1.0e-39	155	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
644854138	298	34.78	4	297	2	295	2.0e-36	146	COG0583	DNA-binding transcriptional regulator, LysR family	297
644854139	631	48.52	1	631	1	635	0.0e+00	877	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
644854140	193	52.11	3	192	1	190	3.0e-73	267	COG3150	Predicted esterase YcpF, UPF0227 family	191
644854141	275	35.61	15	275	1	270	2.0e-37	149	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
644854142	140	73.38	1	139	6	144	8.0e-53	199	COG3151	Uncharacterized protein YqiB, DUF1249 family	147
644854144	470	30.05	7	436	27	455	4.0e-52	199	COG1538	Outer membrane protein TolC	457
644854145	254	37.98	1	204	2	192	2.0e-36	145	COG5463	Uncharacterized conserved protein YgiB, involved in bioifilm formation, UPF0441/DUF1190 family	198
644854146	386	62.98	1	386	1	387	0.0e+00	546	COG0754	Glutathionylspermidine synthase	387
644854147	262	52.06	1	262	4	267	6.0e-86	310	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
644854148	295	58.99	8	285	1	275	2.0e-105	375	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
644854149	682	45.55	1	682	1	604	0.0e+00	486	COG3107	Outer membrane lipoprotein LpoA, binds and activates PBP1a	604
644854150	118	54.39	3	115	1	113	9.0e-31	125	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
644854151	196	67.6	1	179	1	176	2.0e-66	244	COG0279	Phosphoheptose isomerase	176
644854152	191	53.65	1	191	5	196	1.0e-44	172	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
644854155	217	70.05	1	217	1	217	1.0e-88	319	COG3155	Enhancing lycopene biosynthesis protein 2	217
644854157	314	54.17	6	312	2	312	4.0e-125	441	COG1242	Radical SAM superfamily enzyme	312
644854158	1486	60.29	692	1174	1	485	0.0e+00	664	COG0069	Glutamate synthase domain 2	485
644854159	472	46.37	24	470	2	450	0.0e+00	511	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
644854161	167	63.03	3	167	2	155	1.0e-53	202	COG2969	Stringent starvation protein B	155
644854162	213	36.67	11	206	1	208	3.0e-31	128	COG0625	Glutathione S-transferase	211
644854163	130	66.15	1	130	1	130	3.0e-47	180	COG0103	Ribosomal protein S9	130
644854164	142	64.34	1	142	1	143	1.0e-56	212	COG0102	Ribosomal protein L13	148
644854165	376	50.93	1	375	6	367	3.0e-130	458	COG1485	Predicted ATPase	367
644854166	134	66.92	1	130	6	135	2.0e-47	180	COG3105	Uncharacterized membrane-anchored protein YhcB, DUF1043 family	138
644854167	456	48.6	6	360	2	339	2.0e-76	280	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
644854168	354	42.99	35	354	23	345	1.0e-67	250	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
644854169	420	65.95	1	418	1	420	0.0e+00	653	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
644854170	84	71.25	1	80	1	80	5.0e-30	122	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
644854171	97	46.46	1	97	1	99	2.0e-18	84.1	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
644854172	217	54.37	1	206	3	202	2.0e-63	235	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
644854174	260	49.03	1	259	7	264	9.0e-71	260	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
644854175	269	59.77	1	260	3	263	1.0e-105	376	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
644854176	320	51.1	1	319	8	320	3.0e-60	225	COG0530	Ca2+/Na+ antiporter	320
644854177	328	57.43	12	212	1	202	2.0e-71	262	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
644854178	188	64.71	19	188	1	170	2.0e-67	248	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
644854179	189	47.31	2	186	1	185	6.0e-46	177	COG3117	Lipopolysaccharide export system protein LptC	188
644854180	189	50.3	13	177	9	172	6.0e-44	170	COG1934	Lipopolysaccharide export system protein LptA	173
644854181	241	72.73	1	241	2	243	1.0e-114	405	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
644854182	477	54.49	1	477	1	444	0.0e+00	507	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
644854183	95	58.76	1	95	1	97	7.0e-25	105	COG1544	Ribosome-associated translation inhibitor RaiA	110
644854184	162	36.18	8	157	1	150	2.0e-28	118	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
644854185	284	61.46	1	282	1	286	2.0e-109	388	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
644854186	90	44.94	2	90	1	88	7.0e-19	85.6	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
644854187	136	34.85	3	127	21	151	2.0e-17	81.9	COG0782	Transcription elongation factor, GreA/GreB family	151
644854188	446	38.67	15	445	2	448	2.0e-95	343	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
644854189	182	69.95	1	182	1	183	4.0e-57	214	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
644854192	649	27.85	1	647	3	662	2.0e-66	247	COG1289	Uncharacterized membrane protein YccC	674
644854193	315	36.87	1	291	2	337	3.0e-56	212	COG1566	Multidrug resistance efflux pump	352
644854195	314	28.43	3	296	2	295	3.0e-39	155	COG0583	DNA-binding transcriptional regulator, LysR family	297
644854196	481	42.09	18	480	2	454	6.0e-122	431	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
644854197	1284	50.16	8	1278	2	1270	0.0e+00	1198	COG3164	Uncharacterized conserved protein YhdP, contains DUF3971 and AsmA2 domains	1271
644854198	489	50.72	4	489	3	483	0.0e+00	540	COG1530	Ribonuclease G or E	487
644854199	197	54.4	1	181	2	183	2.0e-58	218	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
644854200	162	50	10	162	10	163	5.0e-25	107	COG2891	Cell shape-determining protein MreD	167
644854201	383	38.91	3	276	1	275	2.0e-75	276	COG1792	Cell shape-determining protein MreC	284
644854202	347	70.06	5	346	1	342	0.0e+00	495	COG1077	Actin-like ATPase involved in cell morphogenesis	342
644854203	648	22.58	403	645	6	252	8.0e-30	125	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644854204	328	32.23	1	324	1	326	2.0e-55	209	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
644854205	333	42.96	18	304	1	271	3.0e-65	242	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
644854206	199	49.75	1	199	1	198	4.0e-42	164	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
644854207	150	60.69	6	150	2	146	2.0e-59	221	COG0757	3-dehydroquinate dehydratase	146
644854208	155	50.33	6	155	1	139	1.0e-25	109	COG0511	Biotin carboxyl carrier protein	140
644854209	447	65.7	1	444	1	445	0.0e+00	640	COG0439	Biotin carboxylase	449
644854210	80	68.75	1	80	1	80	8.0e-28	115	COG3924	Uncharacterized membrane protein YhdT	80
644854211	483	66.38	4	476	2	473	0.0e+00	572	COG4145	Na+/panthothenate symporter	473
644854212	295	54.18	1	293	2	300	9.0e-101	359	COG2264	Ribosomal protein L11 methylase PrmA	300
644854213	321	48.15	1	321	2	322	7.0e-99	353	COG0042	tRNA-dihydrouridine synthase	323
644854214	98	91.84	1	98	1	98	2.0e-37	147	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
644854215	350	43.43	1	348	2	339	5.0e-116	411	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
644854217	131	36.22	1	125	6	131	4.0e-20	90.3	COG1917	Cupin domain protein related to quercetin dioxygenase	131
644854218	297	32.99	5	294	2	288	3.0e-38	152	COG0583	DNA-binding transcriptional regulator, LysR family	297
644854219	407	19.6	12	404	2	390	1.0e-15	78.3	COG2814	Predicted arabinose efflux permease, MFS family	394
644854221	380	20.44	115	380	30	258	8.0e-12	65	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
644854222	256	39.1	1	254	2	267	5.0e-39	154	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644854223	221	51.6	1	218	3	221	6.0e-57	213	COG0765	ABC-type amino acid transport system, permease component	222
644854224	343	26.62	4	275	1	273	1.0e-28	120	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644854225	392	59.64	4	392	10	397	0.0e+00	491	COG4597	ABC-type amino acid transport system, permease component	397
644854226	364	37.89	135	361	1	222	9.0e-50	191	COG0765	ABC-type amino acid transport system, permease component	222
644854227	253	62.08	13	252	2	240	3.0e-117	414	COG1126	ABC-type polar amino acid transport system, ATPase component	240
644854232	529	67.23	6	529	1	515	0.0e+00	819	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
644854233	429	62.47	1	427	1	427	0.0e+00	641	COG0151	Phosphoribosylamine-glycine ligase	428
644854235	90	60	1	90	2	91	3.0e-27	113	COG0776	Bacterial nucleoid DNA-binding protein	94
644854236	196	84.02	1	194	1	194	2.0e-90	325	COG3068	Uncharacterized protein YjaG, DUF416 family	194
644854237	224	48.36	1	213	4	212	9.0e-68	249	COG1515	Deoxyinosine 3'endonuclease (endonuclease V)	212
644854238	357	56.94	1	352	2	352	0.0e+00	462	COG0407	Uroporphyrinogen-III decarboxylase	352
644854239	257	51.53	1	254	10	271	1.0e-88	319	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
644854240	149	50.66	1	148	1	152	1.0e-33	135	COG3160	Regulator of sigma D	162
644854241	655	69.35	159	616	1	432	0.0e+00	768	COG0422	Thiamine biosynthesis protein ThiC	432
644854242	211	44.67	11	207	14	207	2.0e-48	185	COG0352	Thiamine monophosphate synthase	211
644854243	249	53.39	1	245	2	252	5.0e-68	251	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
644854244	66	37.88	1	66	3	68	1.0e-10	58.3	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
644854245	259	65.22	1	252	7	259	3.0e-103	368	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
644854246	381	27.2	24	372	3	359	9.0e-81	294	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
644854247	476	37.74	1	465	3	453	2.0e-104	373	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644854255	1407	52.61	20	853	7	808	0.0e+00	933	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
644854257	121	66.94	1	121	1	124	2.0e-22	98	COG0222	Ribosomal protein L7/L12	124
644854258	165	46.63	1	162	1	162	1.0e-36	145	COG0244	Ribosomal protein L10	175
644854259	234	61.84	1	227	1	228	2.0e-81	295	COG0081	Ribosomal protein L1	228
644854260	142	71.63	2	142	1	140	2.0e-51	194	COG0080	Ribosomal protein L11	141
644854261	181	54.86	6	180	2	176	2.0e-58	218	COG0250	Transcription antitermination factor NusG	178
644854262	127	52.05	49	121	1	73	1.0e-12	65	COG0690	Preprotein translocase subunit SecE	73
644854263	394	86.8	1	394	1	394	0.0e+00	728	COG0050	Translation elongation factor EF-Tu, a GTPase	394
644854269	316	60.84	10	295	4	283	4.0e-110	391	COG1072	Panthothenate kinase	283
644854270	319	43.93	84	319	1	238	3.0e-59	222	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
644854271	345	36.64	6	337	7	291	3.0e-82	299	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
644854276	179	61.36	1	175	1	175	4.0e-60	224	COG4635	Protoporphyrinogen IX oxidase, menaquinone-dependent (flavodoxin domain)	175
644854277	483	49.4	1	483	1	488	6.0e-108	384	COG0168	Trk-type K+ transport system, membrane component	499
644854278	204	38.92	1	202	1	202	8.0e-49	186	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
644854279	443	20.88	13	438	11	375	1.0e-37	151	COG0006	Xaa-Pro aminopeptidase	384
644854280	729	44.48	315	612	5	300	2.0e-90	327	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
644854281	387	47.03	1	387	1	392	1.0e-94	340	COG0183	Acetyl-CoA acetyltransferase	392
644854284	233	31.14	1	227	5	224	8.0e-44	170	COG0543	NAD(P)H-flavin reductase	252
644854285	498	59.1	4	492	1	477	0.0e+00	683	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
644854286	162	24.57	1	161	2	176	3.0e-28	118	COG0250	Transcription antitermination factor NusG	178
644854287	340	60.37	9	336	5	330	0.0e+00	523	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
644854288	264	36.54	1	258	3	255	8.0e-65	240	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
644854289	255	54.72	1	251	2	255	2.0e-63	236	COG0805	Sec-independent protein secretion pathway component TatC	255
644854290	190	44.79	1	96	1	94	3.0e-16	78.9	COG1826	Sec-independent protein translocase protein TatA	94
644854291	84	33.33	1	83	1	84	2.0e-12	63.8	COG1826	Sec-independent protein translocase protein TatA	94
644854292	545	46.55	1	517	2	517	0.0e+00	531	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
644854293	202	50.25	1	199	1	199	8.0e-50	190	COG3165	Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain	204
644854294	251	60	13	251	1	238	3.0e-86	311	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
644854295	513	41.57	57	489	14	440	3.0e-92	332	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
644854296	457	57.11	1	457	3	458	0.0e+00	638	COG0165	Argininosuccinate lyase	459
644854297	257	42.05	1	256	2	264	5.0e-64	237	COG0548	Acetylglutamate kinase	265
644854298	334	52.62	1	333	2	342	9.0e-125	440	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
644854299	383	34.31	1	383	8	409	2.0e-67	250	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644854305	364	29.67	117	357	26	254	2.0e-26	113	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
644854307	879	58.49	2	879	3	910	0.0e+00	1210	COG2352	Phosphoenolpyruvate carboxylase	910
644854309	174	33.33	3	147	5	134	1.0e-23	102	COG3600	Uncharacterized phage-associated protein	154
644854310	260	33.07	12	256	1	249	1.0e-34	140	COG2365	Protein tyrosine/serine phosphatase	249
644854311	253	62.15	1	251	3	248	2.0e-87	315	COG2820	Uridine phosphorylase	248
644854312	275	41.63	36	275	1	236	2.0e-57	216	COG0412	Dienelactone hydrolase	236
644854313	756	65.06	422	753	1	330	3.0e-129	456	COG0620	Methionine synthase II (cobalamin-independent)	330
644854314	312	30.67	2	294	1	296	3.0e-34	139	COG0583	DNA-binding transcriptional regulator, LysR family	297
644854315	318	23.45	19	301	8	292	3.0e-07	49.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
644854317	273	58.03	76	268	2	194	1.0e-70	259	COG1045	Serine acetyltransferase	194
644854318	339	56.4	8	335	4	329	6.0e-124	437	COG0240	Glycerol-3-phosphate dehydrogenase	329
644854319	179	59.6	26	176	5	155	2.0e-58	218	COG1952	Preprotein translocase subunit SecB	157
644854320	143	37.61	35	143	2	110	5.0e-17	80.4	COG0607	Rhodanese-related sulfurtransferase	110
644854321	424	48.43	13	424	10	420	9.0e-95	340	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
644854322	309	48.74	4	240	10	247	4.0e-72	265	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
644854323	342	34.56	2	341	1	350	6.0e-76	278	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
644854324	398	47.94	5	391	3	388	8.0e-125	440	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
644854325	310	30.94	1	309	2	311	1.0e-48	187	COG0451	Nucleoside-diphosphate-sugar epimerase	314
644854326	350	38.51	1	346	2	333	1.0e-77	283	COG0859	ADP-heptose:LPS heptosyltransferase	334
644854327	323	32.72	1	322	2	318	4.0e-67	248	COG0859	ADP-heptose:LPS heptosyltransferase	334
644854328	361	33.62	10	356	2	330	1.0e-53	204	COG0859	ADP-heptose:LPS heptosyltransferase	334
644854329	372	22.9	1	372	1	378	2.0e-29	123	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644854331	368	27.1	32	318	3	310	5.0e-31	129	COG0859	ADP-heptose:LPS heptosyltransferase	334
644854332	374	25.39	6	371	3	380	6.0e-38	151	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644854333	427	55.11	4	422	1	419	0.0e+00	528	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
644854334	263	22.73	2	252	1	261	4.0e-14	72.1	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
644854335	159	60.76	1	158	1	158	2.0e-68	251	COG0669	Phosphopantetheine adenylyltransferase	159
644854336	269	57.51	1	269	1	273	4.0e-98	351	COG0266	Formamidopyrimidine-DNA glycosylase	273
644854337	55	62	4	53	1	50	4.0e-10	56.4	COG0267	Ribosomal protein L33	50
644854338	78	66.23	1	76	1	77	8.0e-22	95.4	COG0227	Ribosomal protein L28	77
644854339	221	49.09	2	221	5	224	2.0e-72	265	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
644854340	418	51.26	14	410	1	392	4.0e-120	425	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
644854341	152	51.66	2	152	1	148	3.0e-54	204	COG0756	dUTPase	148
644854342	198	26.82	1	179	3	178	1.0e-06	46.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644854343	213	40.09	3	211	1	201	4.0e-51	194	COG0461	Orotate phosphoribosyltransferase	201
644854344	238	58.4	1	237	8	230	2.0e-79	289	COG0689	Ribonuclease PH	230
644854345	130	51.89	23	128	11	116	2.0e-20	91.5	COG2149	Uncharacterized membrane protein YidH, DUF202 family	120
644854347	335	37.72	1	325	4	329	6.0e-68	251	COG3367	Uncharacterized conserved protein, NAD-dependent epimerase/dehydratase family	339
644854348	321	28.18	1	307	1	328	7.0e-39	154	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644854349	640	54.37	21	581	4	539	0.0e+00	690	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
644854350	518	30.3	4	512	13	547	1.0e-82	301	COG0747	ABC-type transport system, periplasmic component	556
644854351	306	50	1	306	1	316	4.0e-88	318	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644854352	300	49.47	21	300	8	288	2.0e-72	265	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644854353	351	39.48	20	346	1	347	3.0e-72	265	COG3191	L-aminopeptidase/D-esterase	348
644854354	273	42.96	1	269	1	268	9.0e-61	227	COG2362	D-aminopeptidase	274
644854355	320	53.46	1	318	2	307	1.0e-91	329	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
644854356	159	40.51	1	154	1	154	9.0e-32	129	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
644854360	493	22.63	11	493	1	455	3.0e-32	133	COG1538	Outer membrane protein TolC	457
644854361	406	23.92	29	406	2	419	1.0e-27	117	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
644854362	233	49.55	9	229	1	222	7.0e-76	277	COG1136	ABC-type lipoprotein export system, ATPase component	226
644854367	503	24.7	2	317	32	363	5.0e-21	96.2	COG1680	CubicO group peptidase, beta-lactamase class C family	390
644854368	246	51	1	246	3	252	5.0e-83	300	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
644854369	276	54.48	2	265	1	268	3.0e-96	344	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
644854370	300	52.71	26	300	11	287	2.0e-75	275	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644854371	336	44.92	11	335	9	313	2.0e-82	299	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644854372	531	27.11	1	525	11	547	6.0e-67	248	COG0747	ABC-type transport system, periplasmic component	556
644854373	360	40.99	18	360	2	313	1.0e-79	289	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
644854374	302	24.41	1	294	1	297	3.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
644854375	287	57.59	1	287	1	290	2.0e-91	329	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
644854378	73	35.48	12	73	9	70	4.0e-08	49.9	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
644854380	280	40	35	149	1	98	4.0e-20	92.3	COG3561	Phage anti-repressor protein	110
644854385	899	34.17	357	896	25	561	3.0e-113	403	COG5519	Uncharcterized protein, DUF927 family	562
644854390	316	33.77	4	305	3	284	3.0e-54	205	COG4823	Abortive infection bacteriophage resistance protein	299
644854394	365	49.58	5	363	8	346	3.0e-126	445	COG2957	Agmatine/peptidylarginine deiminase	346
644854395	294	34.15	3	284	2	269	5.0e-55	208	COG0388	Predicted amidohydrolase	274
644854396	320	55.72	1	320	1	341	2.0e-114	405	COG0205	6-phosphofructokinase	347
644854397	300	41.55	1	295	3	298	2.0e-77	282	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
644854404	646	26.83	1	565	1	504	6.0e-59	222	COG5301	Phage-related tail fibre protein	587
644854410	232	43.53	3	232	2	229	2.0e-59	222	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644854411	456	35.62	156	455	33	331	5.0e-39	155	COG0642	Signal transduction histidine kinase	336
644854414	179	19.19	11	170	1	160	1.0e-08	53	COG0563	Adenylate kinase or related kinase	178
644854415	154	56.86	1	152	2	153	3.0e-59	220	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
644854417	318	31.94	7	315	1	308	9.0e-36	144	COG0679	Predicted permease	311
644854418	247	37.15	7	247	5	255	1.0e-46	179	COG0584	Glycerophosphoryl diester phosphodiesterase	257
644854419	358	52.71	1	351	1	338	1.0e-127	450	COG3839	ABC-type sugar transport system, ATPase component	338
644854420	282	38.63	5	278	7	276	1.0e-55	210	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
644854421	295	43.79	4	291	2	290	9.0e-58	217	COG1175	ABC-type sugar transport system, permease component	295
644854422	439	27.42	10	434	14	433	1.0e-48	187	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
644854423	560	34.91	144	518	10	406	6.0e-43	169	COG0840	Methyl-accepting chemotaxis protein	408
644854424	559	33.01	132	517	1	408	1.0e-43	171	COG0840	Methyl-accepting chemotaxis protein	408
644854425	542	32.44	132	515	1	406	6.0e-43	169	COG0840	Methyl-accepting chemotaxis protein	408
644854426	157	42.5	1	156	1	156	4.0e-39	153	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
644854428	267	28.14	103	264	5	152	1.0e-14	73.8	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
644854430	545	30.98	132	515	1	406	6.0e-34	139	COG0840	Methyl-accepting chemotaxis protein	408
644854431	394	39.95	5	394	65	453	3.0e-92	332	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644854432	233	62.13	1	233	3	237	6.0e-93	333	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
644854433	256	61.26	3	255	1	250	3.0e-97	347	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
644854434	424	50.3	87	410	4	309	3.0e-61	229	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
644854435	308	48.03	5	307	3	297	9.0e-60	223	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
644854436	370	39.66	17	366	1	358	3.0e-70	259	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
644854439	285	39.36	9	285	62	333	2.0e-72	265	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
644854440	321	42.52	21	321	2	297	6.0e-76	277	COG2177	Cell division protein FtsX	297
644854441	222	67.12	1	222	1	222	6.0e-95	340	COG2884	ABC-type ATPase involved in cell division	223
644854442	452	58.68	124	449	10	340	7.0e-116	411	COG0552	Signal recognition particle GTPase	340
644854443	207	49.73	12	192	1	185	2.0e-60	225	COG0742	16S rRNA G966 N2-methylase RsmD	187
644854444	95	58.89	1	90	1	89	3.0e-19	86.8	COG3776	Uncharacterized conserved protein YhhL, DUF1145 family	91
644854445	108	48.18	1	107	1	108	2.0e-36	143	COG4517	Uncharacterized protein	109
644854446	81	42.11	6	80	2	77	8.0e-21	91.9	COG0425	TusA-related sulfurtransferase	78
644854447	222	42.08	1	215	14	233	6.0e-42	164	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
644854449	405	21.12	9	392	1	383	4.0e-09	56.4	COG2814	Predicted arabinose efflux permease, MFS family	394
644854450	328	29.79	25	314	1	285	8.0e-39	154	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
644854451	67	49.25	1	67	1	67	2.0e-17	80.7	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
644854452	310	31.23	5	305	1	297	2.0e-47	182	COG0524	Sugar or nucleoside kinase, ribokinase family	311
644854453	341	58.49	11	325	1	313	7.0e-116	410	COG3943	Uncharacterized conserved protein	329
644854454	485	20.59	22	452	6	416	5.0e-36	146	COG0612	Predicted Zn-dependent peptidase	438
644854455	428	53.4	2	408	1	404	9.0e-106	377	COG1301	Na+/H+-dicarboxylate symporter	415
644854460	696	23.81	90	523	16	425	8.0e-46	178	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
644854461	271	25.67	1	253	2	258	8.0e-24	104	COG1192	Cellulose biosynthesis protein BcsQ	259
644854469	159	36.48	1	154	1	154	8.0e-33	133	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
644854470	335	49.51	13	319	4	265	9.0e-102	363	COG4608	ABC-type oligopeptide transport system, ATPase component	309
644854471	326	54.4	3	317	1	315	9.0e-123	433	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
644854472	300	52.74	10	300	2	288	5.0e-80	291	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644854473	339	49.56	1	339	1	317	2.0e-97	349	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644854474	535	35.84	1	535	2	553	5.0e-104	371	COG0747	ABC-type transport system, periplasmic component	556
644854475	483	43.15	49	483	1	438	6.0e-114	404	COG3493	Na+/citrate or Na+/malate symporter	438
644854476	450	37.23	53	317	55	328	9.0e-51	194	COG3344	Retron-type reverse transcriptase	328
644854477	240	48.03	2	230	1	224	7.0e-69	253	COG4565	Response regulator of citrate/malate metabolism	224
644854478	537	44.28	1	530	1	532	0.0e+00	530	COG3290	Sensor histidine kinase regulating citrate/malate metabolism	537
644854479	470	35.82	7	469	4	461	1.0e-53	203	COG0471	Di- and tricarboxylate transporter	461
644854480	149	34.29	1	133	7	145	6.0e-24	103	COG0071	Molecular chaperone IbpA, HSP20 family	146
644854481	137	34.04	1	137	7	146	7.0e-28	116	COG0071	Molecular chaperone IbpA, HSP20 family	146
644854482	123	44.44	11	82	4	74	8.0e-15	72.6	COG5645	Uncharacterized conserved protein YceK	80
644854486	231	37.34	1	226	1	231	8.0e-40	157	COG2186	DNA-binding transcriptional regulator, FadR family	241
644854487	394	58.88	1	394	1	362	0.0e+00	527	COG1312	D-mannonate dehydratase	362
644854488	279	36.53	9	278	1	263	8.0e-56	210	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
644854489	144	25	1	141	3	154	7.0e-12	63.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
644854493	394	56.44	1	393	1	403	0.0e+00	555	COG2081	Predicted flavoprotein YhiN	408
644854494	482	23.04	28	419	23	377	8.0e-36	145	COG3950	Predicted ATP-binding protein involved in virulence	440
644854497	287	28.67	1	286	10	255	1.0e-30	127	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
644854498	367	48.26	1	344	1	338	3.0e-109	388	COG3839	ABC-type sugar transport system, ATPase component	338
644854499	348	35.12	107	347	51	281	3.0e-40	159	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
644854500	305	33.1	18	295	16	292	4.0e-35	142	COG1175	ABC-type sugar transport system, permease component	295
644854501	456	23.35	2	451	6	420	3.0e-59	223	COG2182	Maltose-binding periplasmic protein MalE	420
644854502	367	29.18	75	364	5	306	8.0e-35	141	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
644854504	456	61.01	12	447	8	443	0.0e+00	641	COG3048	D-serine dehydratase	443
644854505	141	19.85	5	128	15	150	2.0e-07	48.4	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644854506	325	18.77	11	321	10	333	6.0e-19	88.3	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
644854508	426	21.79	1	423	3	432	3.0e-28	120	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
644854509	295	34.75	17	294	2	281	2.0e-48	185	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
644854510	302	40.42	14	299	4	290	3.0e-59	222	COG1175	ABC-type sugar transport system, permease component	295
644854512	389	28.23	17	386	14	382	2.0e-18	87.6	COG2814	Predicted arabinose efflux permease, MFS family	394
644854513	296	30.98	3	293	2	292	5.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
644854514	392	19.53	1	372	4	381	1.0e-07	51.4	COG2814	Predicted arabinose efflux permease, MFS family	394
644854516	264	33.85	1	253	2	261	2.0e-40	159	COG0300	Short-chain dehydrogenase	265
644854519	560	29.7	1	559	4	549	7.0e-117	414	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
644854520	560	30.19	25	559	1	581	2.0e-122	433	COG0272	NAD-dependent DNA ligase	667
644854521	207	60.53	1	190	1	187	1.0e-78	285	COG0194	Guanylate kinase	191
644854522	91	50	1	73	1	74	2.0e-12	64.2	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
644854523	700	45.89	1	698	6	701	0.0e+00	922	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
644854525	693	57.12	10	686	11	677	0.0e+00	899	COG1200	RecG-like helicase	677
644854526	462	43.18	19	462	3	438	2.0e-105	376	COG2233	Xanthine/uracil permease	451
644854528	313	33.62	35	145	39	152	2.0e-07	50.3	COG2153	Predicted N-acyltransferase, GNAT family	155
644854529	145	62.07	1	145	1	145	5.0e-62	229	COG1490	D-Tyr-tRNAtyr deacylase	145
644854530	203	20.2	1	187	5	201	9.0e-18	83.8	COG1011	FMN phosphatase YigB, HAD superfamily	229
644854531	607	73.34	1	604	1	603	0.0e+00	1063	COG1217	Predicted membrane GTPase involved in stress response	603
644854532	469	51.89	1	469	1	443	0.0e+00	532	COG0174	Glutamine synthetase	443
644854534	349	63.48	1	349	1	356	0.0e+00	475	COG3852	Signal transduction histidine kinase, nitrogen specific	363
644854535	470	52.23	1	470	2	457	0.0e+00	568	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644854537	457	40.6	14	447	1	416	2.0e-123	436	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
644854538	177	51.76	1	169	1	167	2.0e-32	132	COG3078	Ribosome assembly protein YihI, activator of Der GTPase	169
644854539	214	58.59	6	202	3	200	1.0e-76	279	COG0218	GTP-binding protein EngB required for normal cell division	200
644854540	928	61.56	329	928	2	593	0.0e+00	833	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
644854542	328	32.44	1	325	1	331	5.0e-60	224	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
644854543	89	77.27	1	88	1	88	3.0e-38	150	COG3084	Uncharacterized protein YihD, DUF1040 family	88
644854544	191	47.12	1	188	4	191	9.0e-51	193	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
644854545	172	46.63	4	163	2	160	2.0e-37	148	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
644854550	341	45	1	339	3	333	3.0e-96	345	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644854551	310	42.54	7	310	1	311	1.0e-57	216	COG0524	Sugar or nucleoside kinase, ribokinase family	311
644854552	296	42.52	3	296	10	310	7.0e-48	184	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
644854553	322	55.77	10	318	1	307	2.0e-65	243	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
644854554	501	56.05	1	493	5	499	0.0e+00	660	COG1129	ABC-type sugar transport system, ATPase component	500
644854555	139	64.75	1	139	1	135	2.0e-49	187	COG1869	D-ribose pyranose/furanose isomerase RbsD	135
644854556	133	47.33	2	132	1	128	5.0e-35	139	COG3111	Predicted periplasmic protein YdeI with OB-fold, BOF family	128
644854557	223	44.78	1	220	1	229	6.0e-57	214	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644854558	449	30.67	130	449	8	327	4.0e-33	136	COG0642	Signal transduction histidine kinase	336
644854559	622	63.02	1	622	7	627	0.0e+00	855	COG3158	K+ transporter	627
644854560	498	26.69	1	305	5	329	4.0e-45	176	COG0714	MoxR-like ATPase	329
644854561	491	34.53	17	485	2	434	3.0e-100	359	COG2425	Uncharacterized protein, contains a von Willebrand factor type A (vWA) domain	437
644854562	154	35.14	8	154	6	153	1.0e-30	125	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644854563	147	27.45	1	146	1	151	2.0e-24	105	COG0716	Flavodoxin	151
644854564	629	67.52	3	626	1	621	0.0e+00	1024	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
644854565	206	45.97	1	204	1	211	2.0e-62	231	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
644854567	127	52.76	1	126	2	127	3.0e-17	80.7	COG3312	FoF1-type ATP synthase assembly protein I	128
644854568	263	46.99	3	263	6	246	6.0e-53	201	COG0356	FoF1-type ATP synthase, membrane subunit a	246
644854570	156	49.35	3	156	5	158	5.0e-18	83.8	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
644854571	177	43.26	1	176	1	178	2.0e-43	168	COG0712	FoF1-type ATP synthase, delta subunit	178
644854572	513	66.28	1	513	1	502	0.0e+00	825	COG0056	FoF1-type ATP synthase, alpha subunit	504
644854573	287	59.44	5	287	1	286	1.0e-106	379	COG0224	FoF1-type ATP synthase, gamma subunit	287
644854574	460	78.28	1	460	1	465	0.0e+00	838	COG0055	FoF1-type ATP synthase, beta subunit	468
644854575	140	55.47	1	136	1	135	6.0e-37	146	COG0355	FoF1-type ATP synthase, epsilon subunit	135
644854577	456	59.69	4	456	1	459	0.0e+00	653	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
644854578	611	54.32	1	611	1	597	0.0e+00	816	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
644854585	346	37.87	1	326	12	318	5.0e-58	218	COG0226	ABC-type phosphate transport system, periplasmic component	318
644854586	326	45.31	9	323	4	310	6.0e-74	271	COG0573	ABC-type phosphate transport system, permease component	310
644854587	295	52.8	15	293	4	288	1.0e-72	266	COG0581	ABC-type phosphate transport system, permease component	292
644854588	258	64.96	5	258	1	253	2.0e-127	448	COG1117	ABC-type phosphate transport system, ATPase component	253
644854589	242	39.06	6	237	5	237	2.0e-47	182	COG0704	Phosphate uptake regulator	240
644854590	278	37.13	1	263	2	272	3.0e-39	155	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644854591	247	42.79	13	241	8	217	2.0e-50	192	COG0765	ABC-type amino acid transport system, permease component	222
644854592	252	39.27	8	226	4	221	7.0e-45	174	COG0765	ABC-type amino acid transport system, permease component	222
644854593	223	34.53	3	217	1	221	1.0e-40	159	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
644854594	445	61.81	12	441	3	434	2.0e-122	433	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
644854595	246	27.8	1	214	2	222	5.0e-19	88.1	COG2091	Phosphopantetheinyl transferase	223
644854596	177	50	1	164	1	152	3.0e-38	151	COG1142	Fe-S-cluster-containing hydrogenase component 2	165
644854597	667	44.3	197	644	1	448	0.0e+00	492	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
644854598	223	50.42	1	223	1	238	1.0e-56	212	COG1462	Curli biogenesis system outer membrane secretion channel CsgG	252
644854599	117	50.93	9	116	12	118	1.0e-32	131	COG4259	Uncharacterized protein	121
644854600	219	62.44	6	217	4	216	4.0e-79	287	COG4380	Uncharacterized protein	216
644854601	380	50.13	1	380	2	374	1.0e-127	450	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
644854602	327	30.47	9	282	4	275	8.0e-24	104	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
644854603	663	43	1	302	2	307	2.0e-91	330	COG0223	Methionyl-tRNA formyltransferase	307
644854604	299	17.88	1	268	19	259	3.0e-11	63.1	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
644854605	552	33.78	11	524	14	533	3.0e-59	223	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
644854609	203	58.37	4	203	3	211	4.0e-74	270	COG2910	Putative NADH-flavin reductase	211
644854610	128	45.54	14	125	8	119	1.0e-30	125	COG1733	DNA-binding transcriptional regulator, HxlR family	120
644854611	362	48.73	7	357	16	361	2.0e-107	382	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
644854612	257	21.93	1	254	7	247	3.0e-14	72.5	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
644854613	325	37.86	8	315	15	322	7.0e-76	277	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
644854617	570	23.99	2	525	1	452	9.0e-47	181	COG0286	Type I restriction-modification system, DNA methylase subunit	489
644854619	933	29.8	4	920	12	875	0.0e+00	513	COG4096	Type I site-specific restriction endonuclease, part of a restriction-modification system	875
644854620	439	35.82	33	416	1	384	3.0e-65	242	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
644854622	205	28.57	1	204	1	202	2.0e-17	82.9	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
644854625	1027	22.38	10	784	4	698	4.0e-72	267	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
644854627	462	21.81	25	454	1	391	5.0e-20	92.8	COG0732	Restriction endonuclease S subunit	391
644854628	708	29.65	9	485	7	432	5.0e-59	222	COG0286	Type I restriction-modification system, DNA methylase subunit	489
644854631	271	33.19	38	269	20	232	1.0e-18	87	COG2801	Transposase InsO and inactivated derivatives	232
644854632	93	34.04	3	90	4	96	4.0e-06	43.3	COG2963	Transposase and inactivated derivatives	116
644854636	379	26.14	148	369	58	291	3.0e-17	83.3	COG4974	Site-specific recombinase XerD	300
644854637	454	53.81	1	454	1	454	0.0e+00	580	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
644854638	543	50	247	543	5	308	4.0e-78	285	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
644854639	85	60.53	3	78	1	76	2.0e-26	110	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
644854640	119	49.57	6	119	1	115	3.0e-27	113	COG0594	RNase P protein component	117
645945297	622	20.67	85	407	1	309	1.0e-06	48.8	COG0582	Integrase	309
645945309	432	24.92	109	426	82	390	4.0e-23	102	COG0732	Restriction endonuclease S subunit	391
645945314	472	39.29	43	464	1	412	4.0e-100	359	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
645945320	284	35.11	60	284	20	229	3.0e-22	99.3	COG2801	Transposase InsO and inactivated derivatives	232
645945326	1047	51.07	1	1021	2	1006	0.0e+00	955	COG0841	Multidrug efflux pump subunit AcrB	1009
645945334	82	51.35	8	81	1	74	4.0e-18	82.7	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
645945341	156	45.45	1	156	6	179	7.0e-33	133	COG2032	Cu/Zn superoxide dismutase	179
645945350	69	75.38	4	68	6	70	1.0e-21	95.1	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
645945358	99	47.06	1	68	2	69	3.0e-12	63.5	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
645945393	272	33.49	59	272	20	229	8.0e-21	94.3	COG2801	Transposase InsO and inactivated derivatives	232
