gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
650822445	399	50.65	13	391	10	387	4.0e-121	428	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
650822446	354	60.12	6	351	3	343	0.0e+00	514	COG0418	Dihydroorotase	344
650822447	599	42.43	5	500	2	530	0.0e+00	491	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
650822449	357	47.42	1	325	3	312	1.0e-101	363	COG0275	16S rRNA C1402 N4-methylase RsmH	314
650822450	101	27.85	1	79	20	98	2.0e-12	64.2	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
650822451	578	33.06	5	563	1	599	1.0e-115	410	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
650822452	934	42.06	500	922	27	451	5.0e-115	409	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
650822453	390	38.93	22	390	2	316	1.0e-53	203	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
650822454	509	42.01	16	502	11	447	2.0e-109	390	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
650822455	397	40.94	20	396	10	380	5.0e-78	285	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
650822456	357	43.18	5	355	2	357	6.0e-85	307	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
650822457	468	52.34	1	467	3	456	0.0e+00	548	COG0773	UDP-N-acetylmuramate-alanine ligase	459
650822458	315	44.79	4	306	1	317	1.0e-90	326	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
650822459	263	28.03	6	263	26	265	3.0e-30	125	COG1589	Cell division septal protein FtsQ	269
650822460	408	47.95	3	408	2	416	1.0e-124	439	COG0849	Cell division ATPase FtsA	418
650822461	389	52.56	11	319	9	319	1.0e-86	313	COG0206	Cell division GTPase FtsZ	338
650822462	307	56.62	1	301	1	296	4.0e-115	408	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
650822465	912	57.46	1	905	1	822	0.0e+00	1074	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
650822466	492	38.2	49	491	3	447	3.0e-103	369	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
650822467	117	41.03	1	117	16	131	2.0e-32	130	COG1607	Acyl-CoA hydrolase	157
650822468	400	46.92	11	397	11	391	3.0e-121	428	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
650822469	256	43.48	1	250	20	260	5.0e-58	217	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
650822470	620	31.28	6	238	4	243	4.0e-47	183	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
650822471	735	27.91	98	679	106	692	1.0e-75	278	COG1501	Alpha-glucosidase, glycosyl hydrolase family GH31	772
650822475	320	54.23	3	319	20	338	8.0e-111	393	COG1135	ABC-type methionine transport system, ATPase component	339
650822476	219	56.74	5	219	8	222	3.0e-66	244	COG2011	ABC-type methionine transport system, permease component	222
650822477	261	60.9	1	261	3	268	4.0e-92	331	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
650822478	251	38.58	1	250	1	267	1.0e-38	153	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650822480	279	43.55	90	275	37	217	2.0e-37	149	COG0765	ABC-type amino acid transport system, permease component	222
650822481	242	61.25	2	241	1	239	1.0e-103	369	COG1126	ABC-type polar amino acid transport system, ATPase component	240
650822485	362	42.65	28	356	13	346	3.0e-83	302	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
650822486	793	28.57	59	760	57	762	2.0e-105	377	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
650822488	261	45.7	4	257	3	258	7.0e-79	287	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
650822489	409	49.77	1	215	1	206	3.0e-59	222	COG2715	Spore maturation protein SpmA (function unknown)	206
650822490	745	29.11	84	450	30	382	1.0e-46	181	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650822491	131	26.95	1	125	1	138	1.0e-13	68.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650822492	290	24.22	60	282	16	216	1.0e-33	137	COG1451	Predicted metal-dependent hydrolase	223
650822493	244	31.76	13	241	5	231	6.0e-28	117	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
650822494	182	43.02	1	172	5	172	4.0e-46	177	COG0241	Histidinol phosphatase or a related phosphatase	181
650822495	717	41.91	11	716	4	690	0.0e+00	626	COG0751	Glycyl-tRNA synthetase, beta subunit	691
650822496	302	75.77	1	293	4	295	0.0e+00	541	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
650822497	255	42.41	1	252	3	257	4.0e-49	188	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650822498	508	48.37	1	303	1	297	4.0e-104	372	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
650822500	284	42.6	9	282	1	273	4.0e-71	261	COG3777	Hydroxyacyl-ACP dehydratase HTD2, hotdog domain	273
650822501	408	43.65	17	408	5	396	1.0e-111	396	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650822502	270	41.37	7	270	1	275	1.0e-53	203	COG2301	Citrate lyase beta subunit	283
650822503	163	50.31	1	157	1	159	1.0e-39	156	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
650822504	453	35.01	30	437	1	412	2.0e-77	283	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
650822505	233	31.51	1	219	1	200	4.0e-35	141	COG0560	Phosphoserine phosphatase	212
650822508	350	54.87	6	341	1	337	1.0e-127	449	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
650822509	310	48.23	1	309	1	308	2.0e-90	326	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
650822510	624	41.56	6	623	3	638	0.0e+00	613	COG0323	DNA mismatch repair ATPase MutL	638
650822511	432	35.97	173	425	14	231	9.0e-53	201	COG0860	N-acetylmuramoyl-L-alanine amidase	231
650822513	269	33.45	1	269	3	280	2.0e-25	109	COG0679	Predicted permease	311
650822514	328	42.54	6	320	1	312	5.0e-73	268	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650822516	297	25.93	6	297	5	294	3.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
650822519	323	36.34	1	322	1	319	2.0e-75	276	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650822520	698	35.43	7	623	3	596	2.0e-99	356	COG1042	Acyl-CoA synthetase (NDP forming)	598
650822521	324	38.29	5	320	2	316	2.0e-70	259	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650822522	111	28.85	6	102	26	126	4.0e-08	50	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
650822523	381	28.5	2	374	1	389	7.0e-46	178	COG0183	Acetyl-CoA acetyltransferase	392
650822524	233	30.3	4	233	17	246	8.0e-33	133	COG1414	DNA-binding transcriptional regulator, IclR family	246
650822528	163	40.67	10	158	2	151	7.0e-36	143	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
650822529	282	53.87	1	282	18	300	3.0e-100	358	COG4974	Site-specific recombinase XerD	300
650822530	251	40.89	6	251	12	257	2.0e-54	205	COG0725	ABC-type molybdate transport system, periplasmic component	258
650822531	229	52.23	1	223	2	225	2.0e-58	218	COG4149	ABC-type molybdate transport system, permease component	225
650822533	272	40	10	139	1	130	2.0e-28	119	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
650822533	272	44.93	203	271	1	69	1.0e-14	73.8	COG3585	Molybdopterin-binding protein	69
650822535	1119	22.56	13	1097	10	1129	4.0e-76	280	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
650822536	636	39.83	1	458	1	456	2.0e-120	426	COG2812	DNA polymerase III, gamma/tau subunits	515
650822537	108	54.72	1	105	2	105	6.0e-24	102	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
650822538	202	51.81	8	200	4	196	2.0e-70	258	COG0353	Recombinational DNA repair protein RecR	198
650822539	346	26.15	1	341	1	330	4.0e-34	139	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
650822540	269	44.19	4	261	2	247	2.0e-81	295	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
650822541	253	38.06	2	247	12	257	5.0e-48	184	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
650822542	361	42.56	38	326	1	284	9.0e-78	284	COG1533	DNA repair photolyase	297
650822543	379	27.08	3	376	2	377	3.0e-47	182	COG3214	Uncharacterized conserved protein YcaQ, contains winged helix DNA-binding domain	400
650822544	319	37.58	5	314	1	238	1.0e-60	227	COG0176	Transaldolase	239
650822545	365	59.95	1	365	8	366	0.0e+00	544	COG0505	Carbamoylphosphate synthase small subunit	368
650822546	1080	69.48	13	415	1	393	0.0e+00	566	COG0458	Carbamoylphosphate synthase large subunit	400
650822547	253	30.8	4	243	8	256	1.0e-34	140	COG0300	Short-chain dehydrogenase	265
650822548	211	34.16	3	196	2	201	9.0e-35	140	COG0406	Broad specificity phosphatase PhoE	208
650822549	444	37.89	16	432	2	433	7.0e-75	274	COG2233	Xanthine/uracil permease	451
650822550	503	41.56	4	307	3	296	1.0e-83	304	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
650822551	328	38.12	6	325	3	317	4.0e-66	245	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650822552	430	38.46	1	426	10	438	4.0e-115	408	COG0015	Adenylosuccinate lyase	438
650822553	268	28.7	33	262	8	234	7.0e-34	137	COG2188	DNA-binding transcriptional regulator, GntR family	236
650822554	158	51.32	6	157	1	150	1.0e-36	145	COG0782	Transcription elongation factor, GreA/GreB family	151
650822555	190	38.71	6	98	2	94	2.0e-18	86	COG1534	RNA-binding protein YhbY	97
650822556	211	48.31	4	210	1	202	7.0e-61	227	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
650822557	631	60.47	9	598	1	593	0.0e+00	763	COG0465	ATP-dependent Zn proteases	596
650822558	261	50.76	1	260	11	270	4.0e-76	277	COG0294	Dihydropteroate synthase	274
650822559	448	44.98	1	443	4	456	2.0e-114	405	COG1109	Phosphomannomutase	464
650822560	260	36.68	13	258	27	284	2.0e-43	169	COG3176	Putative hemolysin	292
650822561	496	40.77	4	486	4	491	4.0e-114	405	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
650822562	690	51.16	3	688	4	686	0.0e+00	842	COG0855	Polyphosphate kinase	696
650822563	347	36.53	10	325	28	317	4.0e-61	228	COG0226	ABC-type phosphate transport system, periplasmic component	318
650822564	312	43.59	1	306	9	308	3.0e-73	268	COG0573	ABC-type phosphate transport system, permease component	310
650822565	286	41.81	7	286	1	287	1.0e-68	253	COG0581	ABC-type phosphate transport system, permease component	292
650822566	258	66.8	6	258	2	253	3.0e-128	451	COG1117	ABC-type phosphate transport system, ATPase component	253
650822569	342	38.38	245	342	24	122	2.0e-14	73.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650822570	536	32.35	2	531	1	527	7.0e-115	407	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650822571	268	29.23	1	258	2	256	4.0e-40	158	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650822572	403	26.88	20	379	1	366	5.0e-34	139	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650822573	136	35.29	1	134	6	139	2.0e-08	51.5	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
650822575	545	33.46	17	543	1	524	0.0e+00	462	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
650822577	529	52.89	1	238	8	249	3.0e-69	256	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
650822578	629	20.71	6	623	19	646	2.0e-64	241	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
650822579	446	29.83	66	421	5	363	3.0e-43	169	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650822580	626	35.31	1	302	1	293	6.0e-36	146	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650822581	259	45.34	3	245	4	250	4.0e-74	271	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650822582	248	51.87	9	248	1	237	3.0e-77	281	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650822583	1184	34.24	26	716	1	634	0.0e+00	647	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
650822586	372	41.62	1	369	18	387	7.0e-62	231	COG2814	Predicted arabinose efflux permease, MFS family	394
650822587	297	31.42	4	294	1	288	6.0e-41	161	COG0583	DNA-binding transcriptional regulator, LysR family	297
650822588	219	18.75	3	219	2	255	2.0e-08	52.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650822589	614	35.15	36	604	13	567	7.0e-117	414	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650822590	136	35.65	15	129	1	109	1.0e-15	75.3	COG0607	Rhodanese-related sulfurtransferase	110
650822591	100	48.96	3	98	2	95	4.0e-23	99.2	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
650822593	339	31.21	3	295	2	292	1.0e-41	164	COG0583	DNA-binding transcriptional regulator, LysR family	297
650822594	407	28.84	14	380	9	370	3.0e-28	119	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
650822595	1060	46.21	2	1039	1	1009	0.0e+00	977	COG0841	Multidrug efflux pump subunit AcrB	1009
650822596	489	40.34	15	488	1	454	3.0e-59	223	COG1538	Outer membrane protein TolC	457
650822597	338	18.86	83	310	5	212	8.0e-14	71.4	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650822599	310	27.21	3	302	2	297	4.0e-33	135	COG0583	DNA-binding transcriptional regulator, LysR family	297
650822600	382	27.57	3	381	13	406	8.0e-55	208	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
650822601	245	29.84	3	244	8	255	7.0e-05	41.1	COG0730	Uncharacterized membrane protein YfcA	258
650822602	172	30.18	1	168	1	162	1.0e-32	132	COG2062	Phosphohistidine phosphatase SixA	163
650822603	345	26.2	12	338	8	324	5.0e-28	118	COG3274	Surface polysaccharide O-acyltransferase, integral membrane enzyme	332
650822604	403	45.8	16	402	6	395	2.0e-123	436	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
650822605	239	37.14	12	220	17	225	9.0e-30	124	COG1802	DNA-binding transcriptional regulator, GntR family	230
650822607	268	33.72	7	265	1	257	1.0e-38	153	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650822608	510	39.28	1	509	7	527	5.0e-112	398	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650822609	330	31.56	1	330	2	330	3.0e-57	215	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650822610	162	30.32	3	156	5	159	2.0e-16	78.4	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
650822611	438	35.43	52	432	1	377	3.0e-74	272	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650822612	487	33.48	53	487	1	438	7.0e-72	264	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
650822616	283	55.07	1	283	1	294	1.0e-97	349	COG2321	Predicted metalloprotease	295
650822617	208	36.23	2	207	1	206	2.0e-45	175	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
650822618	216	35.68	3	197	11	199	6.0e-16	77.7	COG1994	Zn-dependent protease (includes SpoIVFB)	230
650822619	301	51.19	12	301	5	297	2.0e-87	315	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
650822620	381	26.96	8	381	2	342	2.0e-36	147	COG3317	Uncharacterized lipoprotein	342
650822621	465	58.13	214	459	2	244	2.0e-83	303	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
650822622	567	41.53	10	557	10	509	0.0e+00	475	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
650822623	603	49.05	26	603	16	587	0.0e+00	588	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
650822624	395	36.07	1	389	3	378	6.0e-71	261	COG2850	Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain	383
650822625	873	46.46	4	870	1	843	0.0e+00	922	COG0249	DNA mismatch repair ATPase MutS	843
650822633	1118	25.09	535	1118	28	577	6.0e-35	143	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
650822634	156	38.1	31	155	29	154	2.0e-26	111	COG3915	Uncharacterized protein	155
650822636	220	33.33	13	173	3	170	2.0e-23	102	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650822638	437	28.46	1	378	1	376	6.0e-41	162	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650822639	249	42.8	3	244	23	262	4.0e-58	218	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
650822642	250	46.55	5	235	1	228	9.0e-70	256	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
650822643	328	26.32	15	320	8	327	6.0e-46	178	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
650822647	285	31.11	9	276	34	303	2.0e-33	136	COG0668	Small-conductance mechanosensitive channel	316
650822648	236	28.38	3	227	9	235	1.0e-28	119	COG1414	DNA-binding transcriptional regulator, IclR family	246
650822649	317	42.31	3	313	7	316	5.0e-69	254	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650822650	223	52.78	2	217	1	214	4.0e-70	257	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
650822651	212	50.7	1	212	3	214	1.0e-66	246	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
650822652	257	41.9	5	257	2	239	5.0e-56	211	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
650822653	260	47.1	1	255	4	256	8.0e-66	243	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
650822654	521	50.2	1	243	8	254	4.0e-67	249	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
650822655	292	39.31	4	290	2	268	7.0e-65	240	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
650822656	258	41.48	10	234	1	220	2.0e-46	179	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
650822657	169	49.4	6	169	1	158	3.0e-50	190	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
650822660	483	47.96	1	483	1	464	0.0e+00	564	COG0215	Cysteinyl-tRNA synthetase	464
650822662	320	64.13	4	318	3	317	0.0e+00	480	COG0825	Acetyl-CoA carboxylase alpha subunit	317
650822663	342	31.36	30	311	21	290	2.0e-37	149	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
650822664	420	41.77	1	414	1	447	4.0e-111	395	COG0527	Aspartokinase	447
650822666	396	20.8	139	379	56	303	3.0e-05	43.4	COG0582	Integrase	309
650822671	254	29.41	1	250	2	254	6.0e-30	124	COG1192	Cellulose biosynthesis protein BcsQ	259
650822672	308	21.98	34	260	2	224	2.0e-10	60.3	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
650822677	332	35.48	210	332	4	124	1.0e-12	68	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650822678	1596	32.85	987	1596	32	577	4.0e-60	227	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
650822682	98	40.24	1	82	2	83	7.0e-17	78.8	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
650822690	645	29.26	1	184	2	176	6.0e-12	66.5	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
650822693	97	30.53	1	94	2	95	5.0e-10	55.8	COG3668	Plasmid stabilization system protein ParE	98
650822694	85	45.24	1	83	1	80	1.0e-07	48.5	COG4691	Plasmid stability protein	80
650822695	141	33.57	1	140	3	133	2.0e-16	78.7	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
650822696	187	28.32	1	182	40	265	2.0e-24	105	COG0863	DNA modification methylase	302
650822703	552	25.44	41	552	55	554	2.0e-72	267	COG2831	Hemolysin activation/secretion protein	554
650822705	139	36.76	4	139	1	136	2.0e-26	111	COG0848	Biopolymer transport protein ExbD	137
650822710	340	19.68	35	340	16	318	1.0e-10	61.3	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
650822716	172	26.59	1	171	9	180	4.0e-12	64.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650822717	327	33.44	13	326	8	318	5.0e-39	155	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
650822720	177	23.84	1	168	5	176	4.0e-12	64.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650822721	329	33.44	15	324	10	314	6.0e-39	154	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
650822723	467	42.78	21	371	2	344	3.0e-69	256	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
650822727	361	22.9	8	347	18	338	5.0e-21	95.8	COG3765	LPS O-antigen chain length determinant protein, WzzB/FepE family	347
650822729	169	31.1	7	169	15	177	5.0e-14	70.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650822730	326	32.92	8	321	3	314	2.0e-41	163	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
650822733	172	28.92	9	172	17	181	2.0e-12	65.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650822735	326	34.84	18	321	13	314	2.0e-42	166	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
650822746	559	22.22	129	549	155	587	1.0e-24	108	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
650822752	154	28.78	18	154	12	149	3.0e-10	58.1	COG5642	Uncharacterized conserved protein, DUF2384 family	149
650822753	350	25.33	52	329	16	309	1.0e-11	64	COG5534	Plasmid replication initiator protein	383
650822755	349	31	34	327	15	288	3.0e-42	165	COG0630	Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase	312
650822756	399	30.39	34	384	4	358	3.0e-41	162	COG2948	Type IV secretory pathway, VirB10 components	360
650822757	270	27.51	4	268	5	264	3.0e-33	135	COG3504	Type IV secretory pathway, VirB9 components	265
650822760	228	33.94	7	222	15	230	6.0e-33	134	COG3736	Type IV secretory pathway, component VirB8	239
650822768	691	35.9	1	681	118	787	3.0e-122	432	COG3451	Type IV secretory pathway, VirB4 component	796
650822776	370	22.55	12	366	50	390	5.0e-27	115	COG1459	Type II secretory pathway, component PulF	397
650822777	567	24.52	95	553	67	498	6.0e-50	192	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
650822784	762	50.13	16	758	3	713	0.0e+00	738	COG2217	Cation transport ATPase	713
650822785	136	32.76	4	118	2	114	3.0e-18	84	COG0789	DNA-binding transcriptional regulator, MerR family	124
650822786	713	42.46	2	707	5	710	0.0e+00	654	COG2217	Cation transport ATPase	713
650822787	232	42.92	1	230	2	241	2.0e-45	176	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
650822788	197	36.18	2	197	8	202	9.0e-33	133	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
650822789	168	64.81	1	162	1	162	3.0e-50	190	COG5472	Predicted small integral membrane protein	164
650822791	206	24.73	23	197	5	186	3.0e-29	122	COG2930	Lipid-binding SYLF domain	227
650822792	350	24.56	17	344	17	339	3.0e-15	76.3	COG3515	Predicted component of the type VI protein secretion system	346
650822793	183	55.9	6	165	3	163	5.0e-53	200	COG3516	Predicted component of the type VI protein secretion system	169
650822794	503	61.97	4	500	2	495	0.0e+00	775	COG3517	Predicted component of the type VI protein secretion system	495
650822795	156	24.4	1	156	5	162	9.0e-18	83	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
650822796	179	34.42	19	171	5	151	8.0e-23	100	COG3518	Predicted component of the type VI protein secretion system	157
650822797	629	45.95	1	629	1	621	0.0e+00	599	COG3519	Type VI protein secretion system component VasA	621
650822798	359	36.88	23	339	4	321	4.0e-66	245	COG3520	Predicted component of the type VI protein secretion system	335
650822799	894	39.35	33	893	1	785	0.0e+00	754	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
650822802	185	32.17	24	160	4	144	2.0e-25	108	COG3521	Predicted component of the type VI protein secretion system	159
650822803	443	47.87	1	443	2	446	2.0e-119	423	COG3522	Predicted component of the type VI protein secretion system	446
650822804	443	41.18	13	267	6	260	1.0e-58	220	COG3455	Type VI protein secretion system component VasF	262
650822805	1204	36.53	4	1201	5	1184	0.0e+00	814	COG3523	Type VI protein secretion system component VasK	1188
650822809	782	37.84	2	542	10	547	0.0e+00	514	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
650822812	357	20.93	71	328	14	237	5.0e-19	89.1	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
650822816	351	30.03	2	340	9	345	5.0e-54	205	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
650822817	172	28	2	151	4	152	1.0e-16	79.9	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
650822818	439	37.25	3	438	5	447	4.0e-82	299	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
650822819	216	24.77	1	216	7	223	5.0e-26	111	COG1802	DNA-binding transcriptional regulator, GntR family	230
650822820	291	40.64	1	281	3	285	6.0e-75	274	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
650822821	493	44.42	19	490	1	466	0.0e+00	468	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650822822	399	43.39	1	398	1	392	3.0e-124	438	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
650822823	471	33.19	1	458	6	454	7.0e-88	318	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
650822824	239	31.82	42	231	1	198	5.0e-24	104	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
650822825	204	22.88	50	201	7	158	2.0e-16	79.3	COG3109	sRNA-binding protein	208
650822826	194	48.86	1	176	1	176	1.0e-48	186	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
650822827	386	39.89	10	380	1	349	1.0e-107	383	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
650822828	309	27.62	16	182	22	187	4.0e-08	52.7	COG2236	Hypoxanthine phosphoribosyltransferase	192
650822829	385	29.6	13	369	25	393	9.0e-55	208	COG2124	Cytochrome P450	411
650822831	183	48.22	1	183	3	194	4.0e-54	204	COG2094	3-methyladenine DNA glycosylase Mpg	200
650822832	69	50	4	69	2	67	6.0e-20	89	COG1278	Cold shock protein, CspA family	67
650822833	347	44.51	13	342	7	339	2.0e-91	329	COG1816	Adenosine deaminase	345
650822834	309	39.34	1	242	4	242	3.0e-57	215	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
650822835	252	37.8	2	248	1	251	5.0e-42	164	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650822836	352	35.96	9	350	2	333	2.0e-67	250	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650822837	223	43.66	3	211	1	213	4.0e-48	184	COG0765	ABC-type amino acid transport system, permease component	222
650822838	217	47.14	4	212	10	219	2.0e-54	205	COG0765	ABC-type amino acid transport system, permease component	222
650822839	268	32.46	13	268	6	273	3.0e-33	135	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650822840	264	60.17	22	262	1	240	9.0e-114	402	COG1126	ABC-type polar amino acid transport system, ATPase component	240
650822841	257	22.62	27	223	20	238	7.0e-08	51.4	COG1082	Sugar phosphate isomerase/epimerase	274
650822842	314	40.95	6	311	1	305	1.0e-48	186	COG0524	Sugar or nucleoside kinase, ribokinase family	311
650822843	325	39.94	3	315	2	317	2.0e-80	292	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
650822844	206	47.57	1	206	4	209	2.0e-54	205	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
650822845	123	40.98	2	123	1	121	2.0e-18	84.5	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
650822846	546	26.42	70	445	26	390	2.0e-45	177	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650822847	211	29.25	63	204	43	184	3.0e-13	68.7	COG1525	Endonuclease YncB, thermonuclease family	192
650822848	749	21.35	15	683	10	542	2.0e-35	144	COG0747	ABC-type transport system, periplasmic component	556
650822849	325	34.04	1	325	1	316	3.0e-52	199	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
650822850	485	36.8	222	471	59	288	2.0e-45	177	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
650822851	579	49.47	18	579	4	536	0.0e+00	609	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
650822852	155	38.26	3	151	1	140	1.0e-33	135	COG5319	Uncharacterized protein	142
650822853	185	43.41	1	128	3	131	1.0e-32	132	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
650822855	301	39.51	2	285	1	276	5.0e-62	231	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
650822857	370	41.8	6	364	4	365	1.0e-84	306	COG4394	Uncharacterized protein	370
650822859	865	76.91	3	865	1	852	0.0e+00	1481	COG1049	Aconitase B	852
650822860	91	31.91	1	91	5	98	4.0e-12	63	COG2388	Predicted acetyltransferase, GNAT superfamily	99
650822862	485	46.84	6	478	3	453	4.0e-130	458	COG2079	2-methylcitrate dehydratase PrpD	453
650822863	398	64.96	5	394	2	376	0.0e+00	517	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
650822864	864	50.34	1	859	1	861	0.0e+00	1101	COG1048	Aconitase A	861
650822865	385	48.81	16	385	17	390	1.0e-122	433	COG0372	Citrate synthase	390
650822866	300	61.67	9	295	5	289	2.0e-99	355	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
650822867	648	40.31	71	643	3	557	0.0e+00	464	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
650822868	319	35.86	14	308	5	304	6.0e-56	211	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
650822869	329	31.8	6	329	1	312	1.0e-67	250	COG0039	Malate/lactate dehydrogenase	313
650822870	256	39.41	18	252	1	233	7.0e-49	187	COG2188	DNA-binding transcriptional regulator, GntR family	236
650822871	104	26.85	1	104	23	130	6.0e-07	46.1	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
650822872	126	32.23	6	126	1	116	1.0e-15	75.6	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
650822873	591	51.64	8	577	2	562	0.0e+00	616	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
650822874	238	54.89	5	238	1	232	5.0e-84	304	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
650822875	86	31.08	8	81	14	87	2.0e-10	57.6	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
650822876	434	51.36	30	432	1	386	0.0e+00	470	COG0372	Citrate synthase	390
650822877	295	28.57	3	294	1	290	1.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
650822879	765	54.23	2	435	12	432	0.0e+00	548	COG0281	Malic enzyme	432
650822880	956	59.19	6	946	3	905	0.0e+00	1315	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
650822881	398	53.83	2	397	1	404	2.0e-109	389	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
650822882	475	46.78	1	465	1	454	0.0e+00	510	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
650822883	363	46.94	1	358	9	367	8.0e-119	420	COG1485	Predicted ATPase	367
650822884	452	41.28	7	322	4	314	5.0e-84	305	COG0180	Tryptophanyl-tRNA synthetase	314
650822886	804	57.79	33	804	9	778	0.0e+00	945	COG2183	Transcriptional accessory protein Tex/SPT6	780
650822887	676	36.94	10	672	1	650	3.0e-123	436	COG1199	Rad3-related DNA helicase	654
650822888	258	36.93	1	241	11	241	7.0e-58	217	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
650822889	319	45.21	17	304	2	287	8.0e-72	264	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
650822890	257	45.16	11	255	5	247	2.0e-66	246	COG1496	Copper oxidase (laccase) domain	249
650822891	543	46.97	79	540	1	444	0.0e+00	494	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
650822892	245	39.92	1	242	3	250	1.0e-47	183	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650822893	187	39.38	3	186	2	192	7.0e-46	176	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
650822894	372	48.53	7	372	12	384	8.0e-124	437	COG3146	Predicted N-acyltransferase	387
650822895	370	32.24	5	304	1	290	6.0e-47	181	COG0523	GTPase, G3E family	323
650822897	249	46.2	1	183	4	184	6.0e-38	151	COG1386	Chromosome segregation and condensation protein ScpB	184
650822898	598	46.56	154	393	4	247	3.0e-65	243	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
650822899	164	37.61	3	114	9	125	3.0e-22	98	COG0779	Ribosome maturation factor RimP	153
650822900	494	52.04	159	353	1	190	6.0e-46	178	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
650822901	988	59.41	489	988	3	507	0.0e+00	641	COG0532	Translation initiation factor IF-2, a GTPase	509
650822902	136	38.46	7	120	1	117	1.0e-22	98.7	COG0858	Ribosome-binding factor A	118
650822904	606	65.45	1	605	1	603	0.0e+00	963	COG1217	Predicted membrane GTPase involved in stress response	603
650822905	479	49.05	4	476	1	467	0.0e+00	537	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650822906	208	38.97	1	192	1	195	6.0e-41	160	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
650822907	860	55.07	264	860	2	593	0.0e+00	737	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
650822908	265	40.25	26	261	5	234	2.0e-47	182	COG0412	Dienelactone hydrolase	236
650822909	293	33.56	1	292	15	298	2.0e-39	156	COG0501	Zn-dependent protease with chaperone function	302
650822910	296	22.14	1	265	18	288	4.0e-05	42.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
650822911	289	37.59	1	289	8	285	5.0e-62	231	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
650822912	383	21.99	14	383	2	361	1.0e-35	144	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
650822913	95	39.44	25	95	11	81	1.0e-07	48	COG1722	Exonuclease VII small subunit	81
650822914	304	37.05	7	303	2	321	2.0e-61	229	COG0142	Geranylgeranyl pyrophosphate synthase	322
650822915	594	60.97	1	589	29	625	0.0e+00	872	COG1154	Deoxyxylulose-5-phosphate synthase	627
650822916	273	41.22	12	269	6	278	2.0e-60	225	COG1469	GTP cyclohydrolase FolE2	289
650822917	126	50.89	2	112	1	112	2.0e-33	134	COG0360	Ribosomal protein S6	112
650822919	90	59.46	10	83	2	75	5.0e-21	92.6	COG0238	Ribosomal protein S18	75
650822920	151	53.02	1	149	1	147	2.0e-38	151	COG0359	Ribosomal protein L9	148
650822921	460	48.75	16	456	1	435	0.0e+00	537	COG0305	Replicative DNA helicase	435
650822922	329	49.85	4	328	1	325	4.0e-95	341	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
650822923	545	51.61	82	545	3	436	0.0e+00	521	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
650822924	155	49.67	1	152	1	153	1.0e-51	195	COG1225	Peroxiredoxin	157
650822925	149	32.64	1	144	5	127	7.0e-22	96.5	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
650822926	395	42.46	8	390	5	391	2.0e-106	379	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
650822927	434	51.05	1	324	1	333	6.0e-103	367	COG0460	Homoserine dehydrogenase	333
650822928	469	31	1	466	1	411	4.0e-90	325	COG0498	Threonine synthase	411
650822930	287	43.32	1	274	7	283	2.0e-63	235	COG1562	Phytoene/squalene synthetase	288
650822931	312	25.76	19	312	16	284	4.0e-32	132	COG1562	Phytoene/squalene synthetase	288
650822932	376	43.65	1	373	1	357	1.0e-100	359	COG0787	Alanine racemase	360
650822933	238	41.6	1	232	3	249	2.0e-41	162	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650822934	454	59.74	2	452	1	455	0.0e+00	616	COG1066	Predicted ATP-dependent serine protease	456
650822935	258	28.96	1	258	1	254	5.0e-11	62	COG0730	Uncharacterized membrane protein YfcA	258
650822936	833	37.25	10	832	5	829	0.0e+00	580	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
650822938	366	43.85	10	366	15	363	5.0e-85	308	COG0687	Spermidine/putrescine-binding periplasmic protein	363
650822939	376	47.91	18	375	5	351	5.0e-113	401	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
650822940	305	49.48	10	300	6	285	5.0e-69	254	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
650822941	267	47.74	3	267	7	265	8.0e-57	213	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
650822942	118	33.9	2	118	1	116	2.0e-24	104	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
650822943	226	49.13	3	224	2	227	2.0e-65	242	COG0120	Ribose 5-phosphate isomerase	227
650822944	261	40.91	1	220	5	224	6.0e-40	157	COG0704	Phosphate uptake regulator	240
650822945	90	60	1	90	1	90	2.0e-32	130	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
650822947	392	33.84	4	388	2	390	2.0e-57	216	COG0183	Acetyl-CoA acetyltransferase	392
650822948	516	34.98	1	506	11	527	4.0e-107	382	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650822949	363	22.09	7	346	1	332	1.0e-33	137	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650822950	175	23.53	11	163	12	161	1.0e-05	43	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
650822951	438	34.13	59	433	7	376	9.0e-71	261	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650822952	268	39.7	4	264	2	251	1.0e-39	156	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650822953	473	33.96	59	322	1	264	1.0e-57	217	COG0548	Acetylglutamate kinase	265
650822954	1290	37.12	6	916	9	815	0.0e+00	693	COG1643	HrpA-like RNA helicase	845
650822955	1163	47.29	7	1159	1	1139	0.0e+00	1260	COG0587	DNA polymerase III, alpha subunit	1139
650822956	366	25.71	4	364	3	381	3.0e-34	139	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650822958	248	18.68	1	248	3	247	8.0e-16	77.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
650822962	383	23.59	7	381	2	381	3.0e-27	116	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650822963	238	40.68	1	236	1	220	9.0e-36	143	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
650822964	254	28.69	13	253	1	223	5.0e-21	94.9	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
650822965	318	26.23	7	294	4	292	3.0e-25	109	COG0859	ADP-heptose:LPS heptosyltransferase	334
650822966	591	40.03	22	591	1	567	2.0e-126	446	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650822968	487	44.56	3	487	2	483	0.0e+00	479	COG1530	Ribonuclease G or E	487
650822982	393	43.02	3	360	4	348	1.0e-80	293	COG1566	Multidrug resistance efflux pump	352
650822983	466	32.6	10	465	1	452	2.0e-55	210	COG1538	Outer membrane protein TolC	457
650822984	183	39.34	47	167	4	125	9.0e-19	86.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
650822985	292	20.75	2	289	8	282	5.0e-07	48.6	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
650822986	450	20.82	53	409	2	300	6.0e-35	142	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
650822987	306	32.42	4	293	1	289	4.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
650822988	354	36.81	31	352	10	334	4.0e-59	221	COG2855	Uncharacterized membrane protein YadS	334
650822989	124	34.65	1	120	1	127	6.0e-14	69.5	COG3094	Uncharacterized membrane protein SirB2	129
650822990	663	38.96	13	649	1	589	0.0e+00	539	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
650822991	288	23.68	1	261	10	252	9.0e-24	104	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650822992	124	28.07	1	56	1	57	2.0e-07	47.6	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
650822993	183	57.14	1	181	1	182	3.0e-56	211	COG3803	Uncharacterized conserved protein, DUF924 family	182
650822994	515	45.04	5	515	35	546	0.0e+00	483	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
650822995	175	51.88	1	160	55	214	6.0e-48	183	COG2846	Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains	221
650822996	759	49.93	4	743	2	712	0.0e+00	707	COG3256	Nitric oxide reductase large subunit	717
650822997	543	43.26	15	543	18	547	3.0e-119	422	COG0659	Sulfate permease or related transporter, MFS superfamily	554
650823001	389	30.48	155	350	48	253	2.0e-19	90.4	COG2890	Methylase of polypeptide chain release factors	280
650823003	434	21.48	59	427	4	381	2.0e-19	90.9	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
650823004	512	62.02	15	509	3	493	0.0e+00	742	COG0554	Glycerol kinase	499
650823005	284	40.71	30	282	1	252	1.0e-65	243	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
650823006	360	38.11	1	347	2	338	1.0e-81	297	COG3839	ABC-type sugar transport system, ATPase component	338
650823007	358	38.59	1	354	1	338	1.0e-86	313	COG3839	ABC-type sugar transport system, ATPase component	338
650823008	297	32.18	1	286	1	289	5.0e-46	178	COG1175	ABC-type sugar transport system, permease component	295
650823009	271	38.2	10	271	14	280	3.0e-49	188	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650823010	102	53.95	1	75	6	81	1.0e-15	74.7	COG5477	Predicted small integral membrane protein	97
650823011	576	20.59	55	518	21	432	2.0e-21	97.4	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650823012	528	40.82	24	511	12	513	3.0e-129	455	COG0578	Glycerol-3-phosphate dehydrogenase	532
650823013	192	32.61	8	187	14	197	3.0e-24	105	COG0791	Cell wall-associated hydrolase, NlpC family	197
650823014	443	51.64	1	426	1	413	0.0e+00	564	COG1004	UDP-glucose 6-dehydrogenase	414
650823016	209	32.96	1	179	4	180	1.0e-42	166	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
650823017	384	36.07	17	376	2	363	1.0e-98	353	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
650823023	321	26.01	1	318	1	296	5.0e-35	141	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
650823024	342	47.77	4	339	2	331	4.0e-105	374	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
650823025	693	34.36	79	369	10	280	2.0e-60	227	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
650823026	127	21.28	5	123	3	138	7.0e-07	46.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650823036	190	44.04	5	180	4	196	1.0e-29	123	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650823037	144	38.68	8	110	1	106	1.0e-17	82.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
650823039	91	46.15	22	86	2	66	1.0e-12	64.6	COG2608	Copper chaperone CopZ	71
650823041	561	38.5	101	546	7	454	6.0e-110	391	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
650823042	121	26.42	4	109	1	106	1.0e-08	52.4	COG0789	DNA-binding transcriptional regulator, MerR family	124
650823045	204	38.61	1	187	2	198	2.0e-27	115	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650823049	626	15.24	21	393	1	315	1.0e-10	62.4	COG1106	ATPase/GTPase, AAA15 family	371
650823056	687	27.23	292	678	2	402	5.0e-33	136	COG3464	Transposase	402
650823060	564	30.42	42	489	22	482	3.0e-113	402	COG0069	Glutamate synthase domain 2	485
650823061	144	34.85	21	142	23	152	9.0e-19	86.1	COG2153	Predicted N-acyltransferase, GNAT family	155
650823062	399	23.5	18	375	2	366	1.0e-42	167	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650823063	330	21.48	5	296	1	294	9.0e-20	91.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
650823065	819	44.64	28	749	4	704	0.0e+00	691	COG0557	Exoribonuclease R	706
650823066	249	45.61	9	246	26	257	2.0e-60	225	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
650823067	409	36.41	5	409	7	424	1.0e-109	390	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
650823068	90	63.33	1	90	2	91	6.0e-24	102	COG0776	Bacterial nucleoid DNA-binding protein	94
650823071	303	28.81	11	303	5	294	3.0e-30	125	COG0583	DNA-binding transcriptional regulator, LysR family	297
650823072	472	32.27	5	469	3	468	5.0e-92	331	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
650823073	325	38.46	12	323	9	318	4.0e-62	232	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650823074	296	36.32	95	294	41	241	6.0e-09	55.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
650823075	293	37.74	59	270	1	210	6.0e-37	147	COG0811	Biopolymer transport protein ExbB/TolQ	216
650823076	177	37.5	5	140	2	137	1.0e-32	132	COG0848	Biopolymer transport protein ExbD	137
650823077	224	44.98	1	221	1	228	2.0e-54	205	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650823078	367	29.04	22	353	1	328	2.0e-37	150	COG0642	Signal transduction histidine kinase	336
650823080	129	31.68	6	106	1	101	1.0e-17	82.2	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
650823081	93	47.73	4	91	2	89	6.0e-11	59.4	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
650823082	162	33.55	8	162	5	158	4.0e-30	124	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
650823083	544	29.53	7	532	3	500	3.0e-51	196	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
650823084	114	49.11	1	112	1	111	3.0e-25	106	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
650823085	978	43.43	3	524	1	515	6.0e-120	425	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
650823087	473	37.64	33	464	7	416	7.0e-112	397	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
650823088	122	44.74	1	114	1	114	1.0e-22	98.3	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
650823089	227	29.72	11	218	1	212	5.0e-31	128	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
650823092	401	23.02	7	380	5	333	1.0e-42	167	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
650823093	349	36.8	19	349	7	312	4.0e-77	281	COG0826	Collagenase-like protease, PrtC family	347
650823094	295	22.04	2	291	1	301	4.0e-42	165	COG0826	Collagenase-like protease, PrtC family	347
650823095	205	50.48	1	205	17	224	2.0e-46	179	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
650823096	161	34.62	6	135	6	134	1.0e-19	89.6	COG3154	Predicted lipid carrier protein YhbT, SCP2 domain	168
650823097	250	28.99	17	215	14	217	3.0e-31	128	COG1180	Pyruvate-formate lyase-activating enzyme	260
650823099	573	27.49	5	573	95	681	0.0e+00	545	COG1328	Anaerobic ribonucleoside-triphosphate reductase	700
650823101	479	22.27	7	452	4	470	8.0e-26	111	COG0591	Na+/proline symporter	493
650823102	260	35.69	13	258	6	251	2.0e-32	133	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650823103	435	28.61	24	414	4	336	2.0e-47	183	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
650823104	180	43.75	1	175	4	179	1.0e-40	159	COG3038	Cytochrome b561	181
650823105	464	41.46	2	406	1	382	8.0e-111	394	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
650823106	368	27.49	4	345	24	393	4.0e-72	265	COG0019	Diaminopimelate decarboxylase	394
650823108	648	49.77	11	648	1	616	0.0e+00	620	COG3211	Secreted phosphatase, PhoX family	616
650823109	149	24.81	2	121	1	126	2.0e-07	48.8	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
650823110	233	35.71	1	227	3	251	1.0e-36	146	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650823111	327	38.54	12	325	7	318	6.0e-72	264	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650823112	292	48.99	1	290	1	295	2.0e-76	279	COG3246	Uncharacterized conserved protein, DUF849 family	298
650823113	264	35.8	19	260	2	243	2.0e-46	179	COG1414	DNA-binding transcriptional regulator, IclR family	246
650823114	248	28.46	1	247	2	254	6.0e-39	154	COG1192	Cellulose biosynthesis protein BcsQ	259
650823115	510	25.37	212	476	13	270	6.0e-22	99.3	COG5607	CHAD domain (function unknown)	283
650823117	298	39.53	3	296	1	279	6.0e-56	211	COG2301	Citrate lyase beta subunit	283
650823118	385	39.21	1	378	4	379	1.0e-88	320	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650823120	352	37.46	2	342	57	396	7.0e-75	274	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650823121	378	39.28	8	377	2	386	7.0e-78	284	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650823122	418	31.74	4	413	18	465	1.0e-64	240	COG0427	Acyl-CoA hydrolase	501
650823123	257	28.4	17	256	1	243	2.0e-38	152	COG1414	DNA-binding transcriptional regulator, IclR family	246
650823124	183	31.82	5	158	3	152	4.0e-15	74.6	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
650823125	428	35.53	50	428	2	379	1.0e-63	237	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650823126	343	27.49	4	343	2	331	2.0e-34	139	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650823127	341	24.56	2	340	1	332	8.0e-38	151	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650823128	388	41.67	1	388	1	393	5.0e-83	301	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650823129	153	41.33	1	149	12	158	7.0e-34	136	COG2030	Acyl dehydratase	159
650823130	422	23.49	18	411	12	398	4.0e-14	73	COG2223	Nitrate/nitrite transporter NarK	417
650823132	296	40.34	69	295	1	235	1.0e-45	177	COG0412	Dienelactone hydrolase	236
650823134	422	28.61	1	390	17	370	5.0e-50	192	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
650823135	343	32.22	17	342	1	329	7.0e-65	241	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650823136	224	35.2	32	223	1	195	1.0e-36	146	COG0288	Carbonic anhydrase	207
650823137	178	40.22	3	178	44	215	2.0e-26	112	COG3122	Uncharacterized conserved protein YaiL, DUF2058 family	215
650823138	659	25.82	62	333	41	292	7.0e-24	106	COG0501	Zn-dependent protease with chaperone function	302
650823139	198	43.46	6	196	5	185	3.0e-45	174	COG1704	Uncharacterized conserved protein	185
650823141	146	24.09	1	136	5	139	2.0e-12	65.7	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
650823142	311	35.91	6	297	1	283	2.0e-43	170	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
650823144	445	36.17	8	428	1	403	7.0e-128	450	COG0137	Argininosuccinate synthase	403
650823145	314	52.3	12	308	7	309	1.0e-117	416	COG0078	Ornithine carbamoyltransferase	310
650823147	343	36.96	30	342	3	323	7.0e-80	290	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
650823148	87	55.17	1	87	1	87	9.0e-11	58.4	COG0268	Ribosomal protein S20	88
650823149	518	47.97	1	515	7	516	2.0e-104	373	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
650823150	252	32.58	1	248	1	251	5.0e-31	128	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650823151	218	42.27	1	216	1	177	2.0e-47	182	COG0563	Adenylate kinase or related kinase	178
650823152	254	55.51	1	254	2	246	2.0e-87	315	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
650823153	68	70.91	1	55	1	55	3.0e-16	76.8	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
650823154	359	40.31	14	328	10	314	2.0e-71	263	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
650823155	136	31.65	1	135	1	135	1.0e-18	85.3	COG0848	Biopolymer transport protein ExbD	137
650823156	202	28.08	1	201	12	214	1.0e-30	126	COG0811	Biopolymer transport protein ExbB/TolQ	216
650823158	444	47.22	8	437	5	433	2.0e-117	416	COG1570	Exonuclease VII, large subunit	440
650823159	192	54.82	1	191	2	198	2.0e-72	265	COG0605	Superoxide dismutase	204
650823160	401	43.03	5	401	4	392	2.0e-87	316	COG0183	Acetyl-CoA acetyltransferase	392
650823161	176	43.22	57	174	4	121	4.0e-34	137	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
650823162	80	62.69	14	80	1	67	3.0e-25	106	COG1278	Cold shock protein, CspA family	67
650823163	107	49.04	1	104	4	107	2.0e-29	120	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
650823164	771	46.75	1	742	1	777	0.0e+00	867	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
650823165	421	33.82	5	417	17	418	1.0e-71	264	COG2995	Uncharacterized paraquat-inducible protein A	418
650823166	564	35.14	20	555	2	539	2.0e-114	406	COG3008	Paraquat-inducible protein B	553
650823167	219	29.84	13	201	9	188	7.0e-19	87.3	COG3009	Uncharacterized lipoprotein YmbA	190
650823168	1271	60.48	521	1271	1	769	0.0e+00	958	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
650823169	385	34.36	24	374	3	357	3.0e-54	206	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650823170	310	44.12	1	306	3	294	6.0e-52	198	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650823171	362	44.35	17	352	7	312	6.0e-54	205	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
650823172	276	56.52	14	265	1	250	2.0e-86	312	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650823173	244	55.08	5	239	1	236	7.0e-89	320	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650823174	149	50.34	1	148	1	147	5.0e-48	183	COG0756	dUTPase	148
650823175	212	31.86	4	204	1	204	6.0e-31	127	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
650823176	401	44.44	4	396	2	391	3.0e-99	355	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
650823177	182	38.69	14	177	2	165	9.0e-36	143	COG0597	Lipoprotein signal peptidase	167
650823178	947	46.44	1	941	1	933	0.0e+00	1137	COG0060	Isoleucyl-tRNA synthetase	933
650823179	300	44.59	1	296	19	304	5.0e-83	301	COG0196	FAD synthase	304
650823180	226	53	10	209	2	200	2.0e-71	262	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
650823181	474	40.32	142	451	44	355	2.0e-73	269	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
650823182	402	39.29	4	255	31	282	8.0e-74	271	COG1398	Fatty-acid desaturase	289
650823183	761	44.49	3	660	1	650	0.0e+00	579	COG0210	Superfamily I DNA or RNA helicase	655
650823184	644	45.15	1	526	3	530	0.0e+00	514	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
650823185	298	39.85	10	270	1	248	1.0e-51	196	COG2890	Methylase of polypeptide chain release factors	280
650823186	378	35.71	7	376	16	407	2.0e-82	299	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
650823187	273	49.28	3	273	2	270	3.0e-79	288	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
650823188	418	30.94	25	417	4	392	2.0e-66	246	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
650823190	326	40.14	43	326	20	307	3.0e-67	249	COG1560	Lauroyl/myristoyl acyltransferase	308
650823191	436	39.23	1	434	1	438	4.0e-84	305	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
650823192	218	71.79	24	218	3	197	5.0e-87	313	COG0740	ATP-dependent protease ClpP, protease subunit	200
650823193	435	68.98	16	417	1	402	0.0e+00	671	COG1219	ATP-dependent protease Clp, ATPase subunit	408
650823194	824	64.77	10	797	6	781	0.0e+00	1157	COG0466	ATP-dependent Lon protease, bacterial type	782
650823196	130	43.75	1	64	2	63	5.0e-09	53.5	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
650823197	60	45.9	1	60	7	66	4.0e-11	59.6	COG1724	Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family	66
650823199	220	46.05	4	216	3	199	8.0e-51	193	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
650823200	400	60.61	4	399	1	396	0.0e+00	593	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
650823201	677	64.15	16	675	2	660	0.0e+00	1064	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
650823202	154	36.55	1	145	10	139	1.0e-25	109	COG0394	Protein-tyrosine-phosphatase	139
650823203	171	40	1	145	1	141	5.0e-38	150	COG1959	DNA-binding transcriptional regulator, IscR family	150
650823204	403	58.35	4	387	1	386	0.0e+00	538	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
650823205	128	46.21	1	126	5	145	1.0e-32	132	COG0822	NifU homolog involved in Fe-S cluster formation	150
650823206	107	52.78	1	107	3	110	3.0e-36	143	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
650823208	1118	26.25	519	1118	1	577	2.0e-37	151	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
650823211	290	40.35	1	285	3	266	4.0e-66	245	COG1291	Flagellar motor component MotA	266
650823212	310	29.12	10	267	1	244	1.0e-43	170	COG1360	Flagellar motor protein MotB	244
650823213	686	42.36	6	682	5	711	0.0e+00	622	COG0643	Chemotaxis protein histidine kinase CheA	716
650823214	166	40.24	1	164	2	163	2.0e-36	145	COG0835	Chemotaxis signal transduction protein	165
650823215	545	38.1	171	544	10	408	8.0e-52	198	COG0840	Methyl-accepting chemotaxis protein	408
650823216	279	41.26	19	276	1	263	2.0e-66	245	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
650823217	351	54.09	3	342	1	341	1.0e-110	393	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
650823219	215	61.35	12	215	12	217	7.0e-59	220	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
650823220	386	45.71	1	361	1	361	1.0e-118	420	COG1377	Flagellar biosynthesis protein FlhB	363
650823221	704	56.58	16	701	18	695	0.0e+00	853	COG1298	Flagellar biosynthesis pathway, component FlhA	696
650823222	769	29.9	1	366	1	407	7.0e-64	239	COG1419	Flagellar biosynthesis GTPase FlhF	407
650823223	158	22.67	5	153	2	143	4.0e-06	44.2	COG3418	Flagellar biosynthesis/type III secretory pathway chaperone	146
650823225	236	30.91	18	236	5	220	1.0e-27	116	COG1261	Flagella basal body P-ring formation protein FlgA	220
650823226	137	45.74	9	136	8	131	1.0e-29	121	COG1815	Flagellar basal body rod protein FlgB	133
650823227	138	59.42	1	138	1	137	3.0e-40	157	COG1558	Flagellar basal body rod protein FlgC	137
650823228	228	36.56	1	227	5	221	3.0e-34	138	COG1843	Flagellar hook assembly protein FlgD	222
650823229	412	39.77	1	412	3	422	2.0e-81	296	COG1749	Flagellar hook protein FlgE	423
650823230	248	47.45	1	248	1	251	1.0e-64	239	COG4787	Flagellar basal body rod protein FlgF	251
650823231	261	54.72	1	261	1	263	7.0e-80	290	COG4786	Flagellar basal body rod protein FlgG	265
650823232	227	42.17	6	224	2	230	4.0e-54	204	COG2063	Flagellar basal body L-ring protein FlgH	230
650823233	384	57.54	27	384	11	365	7.0e-117	414	COG1706	Flagellar basal body P-ring protein FlgI	365
650823234	326	39.67	140	316	1	178	1.0e-37	150	COG1705	Flagellum-specific peptidoglycan hydrolase FlgJ	201
650823235	553	33.27	1	553	4	552	1.0e-83	304	COG1256	Flagellar hook-associated protein FlgK	552
650823236	412	19.61	1	408	1	355	5.0e-24	105	COG1344	Flagellin and related hook-associated protein FlgL	360
650823237	434	37.89	17	371	29	408	5.0e-50	192	COG0840	Methyl-accepting chemotaxis protein	408
650823239	570	34.89	168	549	2	408	9.0e-49	188	COG0840	Methyl-accepting chemotaxis protein	408
650823240	262	41.7	2	260	1	258	6.0e-45	174	COG1684	Flagellar biosynthesis protein FliR	258
650823241	89	53.41	1	88	1	88	4.0e-15	73.3	COG1987	Flagellar biosynthesis protein FliQ	89
650823242	257	54.69	12	256	4	248	2.0e-74	272	COG1338	Flagellar biosynthetic protein FliP	248
650823243	116	43.64	6	114	24	129	1.0e-16	78.4	COG3190	Flagellar biogenesis protein FliO	137
650823244	188	40.85	33	174	4	136	8.0e-26	110	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
650823245	330	42.38	5	330	3	327	3.0e-86	312	COG1868	Flagellar motor switch protein FliM	332
650823246	161	30	2	161	7	159	7.0e-20	90.3	COG1580	Flagellar basal body-associated protein FliL	159
650823247	436	21.67	32	436	32	417	1.0e-10	61.2	COG3144	Flagellar hook-length control protein FliK	417
650823248	141	33.09	2	140	10	148	2.0e-11	61.8	COG2882	Flagellar biosynthesis chaperone FliJ	148
650823249	496	55.53	11	480	1	441	0.0e+00	595	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
650823250	249	32.19	16	246	8	231	2.0e-25	109	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
650823251	333	46.2	6	333	12	339	1.0e-81	296	COG1536	Flagellar motor switch protein FliG	339
650823252	563	39.34	12	559	14	545	3.0e-115	409	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
650823253	110	34.55	1	110	2	105	4.0e-11	60	COG1677	Flagellar hook-basal body complex protein FliE	105
650823254	99	43.68	11	96	6	92	4.0e-20	89.5	COG2257	Type III secretion system substrate exporter, FlhB-like	92
650823257	144	40.16	12	133	4	120	8.0e-25	106	COG1516	Flagellin-specific chaperone FliS	132
650823258	471	33.33	1	466	4	482	5.0e-50	192	COG1345	Flagellar capping protein FliD	483
650823260	255	39.32	7	238	27	245	1.0e-46	180	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
650823261	444	35.69	3	271	2	270	4.0e-33	135	COG1344	Flagellin and related hook-associated protein FlgL	360
650823262	295	38.74	159	269	3	104	1.0e-18	87.2	COG1803	Methylglyoxal synthase	142
650823263	912	30.36	372	912	77	577	1.0e-55	212	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
650823264	506	57.54	5	506	2	502	0.0e+00	698	COG1190	Lysyl-tRNA synthetase (class II)	502
650823265	250	28.45	1	233	3	224	2.0e-26	112	COG0300	Short-chain dehydrogenase	265
650823266	359	64.85	122	359	1	239	2.0e-99	356	COG1186	Protein chain release factor B	239
650823267	359	17.96	28	356	10	317	4.0e-15	76.1	COG1275	Tellurite resistance protein TehA and related permeases	329
650823268	426	49.34	47	423	1	377	5.0e-94	338	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650823269	182	39.74	7	162	13	166	7.0e-25	106	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
650823270	334	39.16	3	334	1	332	2.0e-96	346	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650823271	286	39.71	10	281	3	267	2.0e-53	202	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
650823272	414	48.46	188	414	60	286	1.0e-61	230	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
650823273	355	24.44	1	351	2	354	2.0e-36	146	COG0687	Spermidine/putrescine-binding periplasmic protein	363
650823274	373	44.66	9	363	5	350	2.0e-114	405	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
650823275	418	25.07	1	311	1	320	1.0e-30	127	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
650823276	1173	20	392	1158	208	971	9.0e-29	123	COG4717	Uncharacterized protein YhaN	984
650823278	204	30.83	53	183	45	177	1.0e-19	89.9	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
650823279	257	49.8	1	246	2	248	1.0e-79	289	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
650823280	331	28.96	1	323	2	322	1.0e-34	141	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
650823281	257	33.47	11	256	10	255	9.0e-32	130	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
650823282	281	25.1	19	261	6	260	2.0e-07	50	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650823283	312	48.24	121	290	2	162	2.0e-42	166	COG1045	Serine acetyltransferase	194
650823285	251	39.42	18	121	1	103	1.0e-22	100	COG1733	DNA-binding transcriptional regulator, HxlR family	120
650823286	314	40.88	162	287	1	134	7.0e-29	121	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
650823287	326	49.21	1	314	1	315	4.0e-74	271	COG0385	Predicted Na+-dependent transporter	319
650823288	342	25.88	31	341	3	290	4.0e-08	52.6	COG5006	Threonine/homoserine efflux transporter RhtA	292
650823289	574	40.56	54	553	13	489	7.0e-109	388	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
650823290	313	23.6	80	297	59	308	2.0e-19	90.1	COG4255	Uncharacterized protein	318
650823291	423	44	1	422	3	407	2.0e-103	369	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
650823292	238	45.74	10	231	2	224	3.0e-75	274	COG1136	ABC-type lipoprotein export system, ATPase component	226
650823293	272	40.91	1	263	2	254	5.0e-67	247	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
650823294	323	35.96	4	320	3	317	6.0e-57	214	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650823296	416	28.53	1	367	3	347	3.0e-40	159	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
650823297	138	27.93	28	137	14	124	4.0e-09	53.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
650823298	832	28.75	508	826	6	293	5.0e-52	199	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
650823299	410	42.15	53	409	2	357	4.0e-101	361	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
650823300	357	56.51	13	345	2	323	0.0e+00	478	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
650823301	431	39.12	2	431	1	404	6.0e-99	354	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
650823302	471	44.52	1	461	2	454	1.0e-126	446	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
650823303	287	22.11	1	287	12	280	1.0e-11	64	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650823304	256	45.26	1	231	22	249	9.0e-48	183	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
650823305	193	41.18	40	191	1	151	3.0e-34	138	COG0782	Transcription elongation factor, GreA/GreB family	151
650823306	1357	33.99	171	1023	2	735	0.0e+00	673	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
650823307	486	30.32	255	475	1	170	2.0e-34	141	COG0516	IMP dehydrogenase/GMP reductase	170
650823309	399	23.26	1	377	4	388	2.0e-09	57.5	COG2814	Predicted arabinose efflux permease, MFS family	394
650823310	528	68.1	203	528	1	315	0.0e+00	552	COG0519	GMP synthase, PP-ATPase domain/subunit	315
650823311	400	19.29	84	391	5	309	3.0e-07	50.3	COG0582	Integrase	309
650823312	96	38.6	24	80	14	70	2.0e-09	53.8	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
650823313	317	30.07	44	317	3	281	7.0e-31	127	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650823314	365	21.59	1	345	1	328	1.0e-28	120	COG3203	Outer membrane protein (porin)	354
650823318	437	22.35	12	433	7	391	1.0e-13	71.8	COG2814	Predicted arabinose efflux permease, MFS family	394
650823319	779	38.18	3	381	39	409	2.0e-54	207	COG3903	Predicted ATPase	414
650823324	1053	36.19	228	655	11	411	5.0e-60	226	COG3903	Predicted ATPase	414
650823325	227	14.01	9	206	1	205	3.0e-22	98.7	COG1335	Nicotinamidase-related amidase	205
650823326	91	53.41	1	88	1	88	8.0e-23	98.5	COG4317	Xanthosine utilization system component, XapX domain	93
650823327	631	43.49	5	538	4	533	0.0e+00	538	COG1574	Predicted amidohydrolase YtcJ	535
650823330	203	42.23	1	198	3	206	2.0e-42	165	COG0655	Multimeric flavodoxin WrbA	207
650823334	527	37.11	112	269	3	157	4.0e-25	109	COG3436	Transposase	157
650823336	532	40	116	274	2	157	1.0e-24	108	COG3436	Transposase	157
650823340	295	23	13	292	1	281	2.0e-17	83.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650823341	208	15.59	15	193	1	185	1.0e-18	86.4	COG1335	Nicotinamidase-related amidase	205
650823342	98	36.71	1	79	1	78	1.0e-12	65	COG1359	Quinol monooxygenase YgiN	100
650823343	101	36.84	7	100	5	98	4.0e-15	73	COG2388	Predicted acetyltransferase, GNAT superfamily	99
650823346	528	22.69	65	399	61	384	1.0e-12	68.3	COG2814	Predicted arabinose efflux permease, MFS family	394
650823348	296	38.77	1	272	7	275	2.0e-60	225	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
650823349	246	42.63	2	243	1	249	2.0e-38	152	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650823350	133	28.32	22	132	19	128	1.0e-13	68.8	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
650823352	683	34.84	19	672	1	642	7.0e-128	451	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
650823353	376	24.06	2	369	8	381	3.0e-16	79.9	COG2814	Predicted arabinose efflux permease, MFS family	394
650823354	313	31.02	3	300	2	296	1.0e-38	153	COG0583	DNA-binding transcriptional regulator, LysR family	297
650823356	129	36.92	3	129	1	129	4.0e-25	106	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
650823357	335	48.94	7	334	12	339	3.0e-99	355	COG2130	NADPH-dependent curcumin reductase CurA	340
650823358	315	43.84	1	271	3	259	2.0e-66	246	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
650823361	532	40	116	274	2	157	1.0e-24	108	COG3436	Transposase	157
650823363	328	29.63	34	324	3	295	2.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
650823366	136	23.74	6	130	1	136	2.0e-06	45.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650823368	491	39.46	8	483	3	472	2.0e-109	389	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650823370	299	32.67	7	298	2	291	1.0e-54	206	COG4823	Abortive infection bacteriophage resistance protein	299
650823372	637	63.98	136	605	2	432	0.0e+00	743	COG0422	Thiamine biosynthesis protein ThiC	432
650823374	313	20.99	135	313	69	243	9.0e-14	71.2	COG3279	DNA-binding response regulator, LytR/AlgR family	244
650823375	381	27.32	2	361	6	365	2.0e-36	147	COG1680	CubicO group peptidase, beta-lactamase class C family	390
650823377	527	28.53	16	379	2	365	1.0e-39	158	COG1680	CubicO group peptidase, beta-lactamase class C family	390
650823379	153	56.67	1	150	2	149	2.0e-47	181	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
650823380	338	31.4	7	334	2	276	5.0e-46	178	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
650823381	200	26	12	191	7	198	7.0e-19	87.3	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
650823382	756	24.26	38	756	24	722	3.0e-70	260	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
650823383	155	49.67	1	152	3	155	5.0e-54	203	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
650823384	254	20.68	1	234	4	227	2.0e-16	79.9	COG1011	FMN phosphatase YigB, HAD superfamily	229
650823390	847	42.42	37	591	8	565	0.0e+00	478	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
650823391	286	32.32	5	196	41	234	3.0e-38	152	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
650823392	124	29.09	27	120	23	127	3.0e-06	44.2	COG3474	Cytochrome c2	135
650823393	286	31.09	183	286	19	133	4.0e-06	45.7	COG3474	Cytochrome c2	135
650823394	331	38.55	85	328	1	248	7.0e-53	201	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650823396	322	35.33	3	318	4	316	2.0e-68	252	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650823397	287	41.05	2	283	1	284	2.0e-56	213	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
650823398	132	45.45	15	132	2	122	6.0e-25	106	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
650823399	219	32.73	1	219	4	222	4.0e-34	137	COG1802	DNA-binding transcriptional regulator, GntR family	230
650823400	310	35.21	38	304	1	255	5.0e-52	198	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
650823401	261	38.22	9	258	3	251	1.0e-39	156	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650823402	227	54.59	17	221	2	206	2.0e-72	265	COG1535	Isochorismate hydrolase	218
650823403	467	20.33	100	397	19	302	1.0e-09	58.3	COG3391	DNA-binding beta-propeller fold protein YncE	381
650823404	1322	34.95	244	887	1	642	1.0e-108	388	COG1020	Non-ribosomal peptide synthetase component F	642
650823405	70	40.58	1	69	3	71	1.0e-11	61.5	COG3433	Aryl carrier domain	74
650823406	548	54.9	1	541	4	540	0.0e+00	697	COG1021	Non-ribosomal peptide synthetase component E (peptide arylation enzyme)	542
650823407	270	25.47	5	268	9	261	7.0e-28	117	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
650823408	376	26.42	1	347	10	319	3.0e-36	146	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
650823409	261	40.16	1	253	2	254	5.0e-60	224	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
650823410	350	42.56	18	350	1	332	6.0e-54	205	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
650823411	257	27.12	1	230	1	236	1.0e-19	90.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650823413	153	30.67	1	144	5	154	8.0e-23	99.8	COG1522	DNA-binding transcriptional regulator, Lrp family	154
650823414	299	25.68	1	283	1	279	2.0e-09	56.7	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
650823415	119	32.76	1	116	5	120	8.0e-13	65.9	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
650823416	241	47.56	15	239	6	229	2.0e-48	185	COG1346	Putative effector of murein hydrolase	230
650823417	553	32.85	9	553	1	534	3.0e-112	399	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650823418	160	49.38	1	160	4	165	1.0e-43	168	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
650823419	298	39.02	9	293	5	291	2.0e-61	229	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
650823421	308	38.31	1	305	1	292	1.0e-71	263	COG1131	ABC-type multidrug transport system, ATPase component	293
650823422	494	41.52	222	487	11	284	6.0e-53	202	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
650823423	282	19.52	6	212	7	178	5.0e-03	35.3	COG0560	Phosphoserine phosphatase	212
650823424	152	58.16	1	141	12	152	5.0e-44	170	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
650823425	316	39.67	25	315	13	312	4.0e-67	248	COG1619	Muramoyltetrapeptide carboxypeptidase LdcA (peptidoglycan recycling)	313
650823426	533	41.04	1	532	3	530	0.0e+00	568	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
650823427	200	32.99	1	188	3	196	6.0e-44	170	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
650823429	430	61.02	1	428	5	435	3.0e-120	425	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
650823430	354	56.1	1	344	1	338	1.0e-122	433	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
650823431	212	47.29	7	209	2	200	7.0e-43	166	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
650823432	252	53.6	1	244	1	250	8.0e-85	306	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
650823433	272	49.51	69	271	5	206	3.0e-58	218	COG2518	Protein-L-isoaspartate O-methyltransferase	209
650823434	263	33.09	62	263	3	267	8.0e-27	114	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
650823439	472	62.42	15	461	1	447	0.0e+00	632	COG0165	Argininosuccinate lyase	459
650823440	430	18.13	91	414	19	316	6.0e-17	82.2	COG0668	Small-conductance mechanosensitive channel	316
650823441	112	71.43	1	112	1	112	2.0e-38	150	COG0347	Nitrogen regulatory protein PII	112
650823442	178	47.75	1	178	1	178	1.0e-53	202	COG4681	Uncharacterized conserved protein YaeQ, suppresses RfaH defect	181
650823443	198	25.29	10	181	6	169	4.0e-13	68	COG3161	4-hydroxybenzoate synthetase (chorismate-pyruvate lyase)	174
650823444	244	39.29	2	244	1	240	3.0e-54	205	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
650823445	284	47.31	3	280	2	274	2.0e-91	329	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
650823446	259	35.69	10	253	5	257	1.0e-39	156	COG0584	Glycerophosphoryl diester phosphodiesterase	257
650823448	217	32.52	34	215	10	215	4.0e-25	108	COG2755	Lysophospholipase L1 or related esterase	216
650823449	222	61.82	5	221	7	226	3.0e-73	268	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
650823450	433	32.36	54	429	3	376	1.0e-62	234	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650823451	168	21.15	1	155	5	157	7.0e-10	56.9	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
650823452	323	27.91	2	323	6	329	1.0e-46	180	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650823454	756	41.77	57	754	17	701	0.0e+00	801	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
650823455	67	47.83	1	66	1	69	7.0e-12	62.2	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
650823456	202	53.04	1	181	8	187	4.0e-65	240	COG0194	Guanylate kinase	191
650823458	220	36.81	26	205	15	194	2.0e-29	122	COG3963	Phospholipid N-methyltransferase	194
650823459	262	43.4	1	259	1	261	4.0e-81	294	COG0708	Exonuclease III	261
650823461	393	41.34	1	393	1	392	2.0e-86	313	COG0183	Acetyl-CoA acetyltransferase	392
650823462	242	22.57	2	208	26	249	5.0e-22	98.1	COG0421	Spermidine synthase	282
650823463	322	53.54	1	322	1	322	2.0e-85	309	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
650823464	297	62.5	1	296	1	293	1.0e-88	319	COG4120	ABC-type uncharacterized transport system, permease component	293
650823465	264	66.92	1	263	1	263	2.0e-107	382	COG1101	ABC-type uncharacterized transport system, ATPase component	263
650823467	433	38.46	8	378	6	369	3.0e-30	126	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
650823468	1064	50.15	1	1026	2	1007	0.0e+00	960	COG0841	Multidrug efflux pump subunit AcrB	1009
650823469	510	41.77	16	488	1	455	4.0e-71	262	COG1538	Outer membrane protein TolC	457
650823470	244	62.24	2	239	1	241	2.0e-86	312	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
650823471	191	23.3	1	190	1	206	4.0e-12	64.6	COG0778	Nitroreductase	207
650823472	479	31.65	7	454	6	454	5.0e-86	312	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
650823473	196	37	4	195	10	207	3.0e-34	138	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
650823474	687	48.99	1	687	7	682	0.0e+00	780	COG0339	Zn-dependent oligopeptidase	683
650823475	283	59.79	4	283	1	281	7.0e-107	380	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
650823476	208	53.3	9	205	6	202	9.0e-66	243	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
650823479	903	65.95	15	900	8	884	0.0e+00	1343	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
650823480	572	43.6	131	572	5	403	4.0e-97	348	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
650823481	581	51.1	115	565	5	454	0.0e+00	477	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
650823482	469	39.19	6	468	1	423	5.0e-115	408	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
650823483	251	21.81	17	248	8	222	1.0e-08	53.5	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
650823484	162	34.36	1	162	1	163	2.0e-19	88.4	COG1286	Uncharacterized membrane protein, required for colicin V production	182
650823485	499	49.59	1	483	4	468	0.0e+00	578	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
650823486	155	23.53	3	155	18	170	2.0e-05	41.9	COG1495	Disulfide bond formation protein DsbB	170
650823487	852	41.75	2	848	17	862	0.0e+00	750	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
650823488	269	49.03	1	256	1	253	4.0e-91	327	COG0024	Methionine aminopeptidase	255
650823489	249	59.76	4	249	6	248	6.0e-95	340	COG0052	Ribosomal protein S2	252
650823490	292	53.38	1	290	1	296	9.0e-85	306	COG0264	Translation elongation factor EF-Ts	296
650823491	238	62.23	6	237	5	237	3.0e-87	314	COG0528	Uridylate kinase	238
650823492	186	53.76	1	186	2	187	1.0e-62	232	COG0233	Ribosome recycling factor	187
650823493	250	51.97	16	244	17	245	2.0e-83	302	COG0020	Undecaprenyl pyrophosphate synthase	245
650823494	287	32.73	1	275	1	254	2.0e-30	126	COG0575	CDP-diglyceride synthetase	265
650823495	400	52.55	4	395	2	379	0.0e+00	495	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
650823496	444	33.48	1	443	1	374	1.0e-48	187	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
650823497	778	40.68	16	778	7	766	0.0e+00	627	COG4775	Outer membrane protein assembly factor BamA	766
650823498	187	34.39	33	185	11	167	2.0e-18	85.8	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
650823499	361	43.32	25	361	10	336	1.0e-85	309	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
650823500	150	53.42	3	146	4	144	1.0e-42	165	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
650823501	264	55.56	3	263	4	260	7.0e-99	353	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
650823502	415	38.13	3	415	2	380	3.0e-97	349	COG0763	Lipid A disaccharide synthetase	381
650823503	220	57.45	21	205	2	189	9.0e-62	230	COG0164	Ribonuclease HII	199
650823504	264	33.33	4	260	1	255	1.0e-43	170	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
650823505	277	46.74	8	277	4	273	7.0e-83	300	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
650823506	788	48.48	1	788	2	737	0.0e+00	744	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
650823507	200	21.08	1	185	6	188	2.0e-10	59.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650823509	1048	52.71	1	1029	2	1009	0.0e+00	993	COG0841	Multidrug efflux pump subunit AcrB	1009
650823510	475	40.26	9	474	1	457	2.0e-70	260	COG1538	Outer membrane protein TolC	457
650823511	435	35.73	4	416	2	397	5.0e-90	325	COG1252	NADH dehydrogenase, FAD-containing subunit	405
650823512	241	45.16	85	237	15	167	9.0e-34	137	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
650823513	155	56.38	1	149	6	153	2.0e-52	198	COG0691	tmRNA-binding protein	153
650823514	128	47.66	1	127	17	144	7.0e-39	152	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
650823515	104	45.36	3	99	2	98	1.0e-15	74.6	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
650823516	384	43.26	1	382	1	392	4.0e-87	315	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650823517	381	30.73	7	210	4	196	7.0e-34	138	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650823518	294	47.1	2	293	1	286	2.0e-73	269	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
650823519	348	28.61	8	346	17	304	4.0e-43	169	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
650823520	338	39.17	1	335	4	339	3.0e-93	335	COG1559	Cell division protein YceG, involved in septum cleavage	342
650823521	216	43.2	2	207	1	205	6.0e-54	203	COG0125	Thymidylate kinase	208
650823523	256	49.22	1	253	2	256	5.0e-81	294	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
650823526	232	32.21	1	201	1	201	2.0e-36	146	COG0625	Glutathione S-transferase	211
650823527	164	61.49	1	161	2	162	3.0e-72	263	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
650823528	187	34.16	26	181	1	156	3.0e-30	124	COG1225	Peroxiredoxin	157
650823530	374	52.94	18	371	1	345	3.0e-109	388	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
650823531	310	71.38	33	308	12	287	3.0e-115	408	COG4208	ABC-type sulfate transport system, permease component	287
650823532	287	63.3	14	280	5	271	1.0e-76	280	COG0555	ABC-type sulfate transport system, permease component	274
650823533	336	72.48	10	335	22	348	0.0e+00	514	COG1613	ABC-type sulfate transport system, periplasmic component	348
650823534	449	36.73	1	447	2	433	5.0e-107	381	COG4091	Predicted homoserine dehydrogenase, contains C-terminal SAF domain	438
650823536	475	47.91	3	451	2	455	0.0e+00	496	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
650823537	335	43.9	1	335	3	345	7.0e-74	270	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
650823539	66	32.35	1	65	3	70	5.0e-08	49.2	COG2608	Copper chaperone CopZ	71
650823540	149	59.46	1	147	2	149	2.0e-50	191	COG3241	Azurin	151
650823541	291	38.18	1	272	7	274	2.0e-61	229	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
650823542	344	25.79	1	336	1	380	1.0e-31	130	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650823543	292	37.39	14	248	1	234	5.0e-62	231	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
650823544	140	39.29	6	117	5	116	1.0e-31	129	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
650823545	327	64.71	1	322	1	320	0.0e+00	500	COG0435	Glutathionyl-hydroquinone reductase	324
650823546	189	44.5	1	189	1	191	7.0e-41	160	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
650823547	190	33.51	9	188	6	191	4.0e-26	111	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
650823548	168	43.03	2	165	16	180	2.0e-32	131	COG3038	Cytochrome b561	181
650823549	307	33.56	9	299	4	291	1.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
650823550	401	35.39	10	186	6	183	4.0e-32	132	COG2059	Chromate transport protein ChrA	195
650823551	428	47.06	1	424	3	424	3.0e-86	312	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
650823552	128	31.48	2	103	35	136	2.0e-14	71.8	COG0394	Protein-tyrosine-phosphatase	139
650823553	173	33.81	9	142	6	139	2.0e-26	111	COG0394	Protein-tyrosine-phosphatase	139
650823554	113	35.87	1	92	10	99	1.0e-11	61.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650823555	252	30.77	38	229	1	183	1.0e-35	143	COG0431	NAD(P)H-dependent FMN reductase	184
650823556	555	40.5	190	521	51	408	6.0e-35	142	COG0840	Methyl-accepting chemotaxis protein	408
650823558	309	36.48	3	304	1	291	1.0e-61	230	COG1230	Co/Zn/Cd efflux system component	296
650823559	468	32.22	140	464	9	328	7.0e-40	158	COG0642	Signal transduction histidine kinase	336
650823560	227	43.61	1	222	1	226	6.0e-56	210	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650823562	292	42.55	19	292	57	321	7.0e-68	250	COG3667	Uncharacterized protein involved in copper resistance	321
650823565	138	44.07	3	119	7	122	1.0e-32	132	COG3019	Uncharacterized conserved protein	149
650823566	199	32	1	198	5	203	7.0e-34	137	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
650823567	321	32.18	1	317	4	316	5.0e-67	248	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650823568	418	37.56	1	401	7	396	3.0e-93	335	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650823569	234	35.92	1	201	1	200	9.0e-39	153	COG0625	Glutathione S-transferase	211
650823570	336	27.48	1	312	1	297	7.0e-32	131	COG0583	DNA-binding transcriptional regulator, LysR family	297
650823571	413	40.34	1	412	2	396	1.0e-92	333	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650823572	313	29.79	13	302	2	288	9.0e-34	137	COG0583	DNA-binding transcriptional regulator, LysR family	297
650823573	261	38.75	18	254	14	251	3.0e-41	162	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650823574	321	41.53	8	320	9	319	1.0e-71	263	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650823575	396	44.9	6	396	8	386	2.0e-115	409	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650823579	493	35.98	1	486	8	533	4.0e-108	385	COG0659	Sulfate permease or related transporter, MFS superfamily	554
650823580	180	31.43	7	171	1	175	3.0e-18	84.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650823583	251	47.68	1	237	38	270	4.0e-74	271	COG3220	Uncharacterized conserved protein, UPF0276 family	282
650823585	132	30.77	3	123	23	139	2.0e-07	48.1	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
650823586	685	22.08	4	377	1	377	8.0e-41	162	COG1680	CubicO group peptidase, beta-lactamase class C family	390
650823587	249	36.87	57	248	1	195	5.0e-36	144	COG0288	Carbonic anhydrase	207
650823588	321	26.72	205	320	14	124	8.0e-10	58	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650823589	479	37.25	1	478	6	487	1.0e-75	277	COG0168	Trk-type K+ transport system, membrane component	499
650823590	465	31.62	1	232	1	225	3.0e-36	146	COG0569	Trk K+ transport system, NAD-binding component	225
650823591	317	30.69	1	197	2	203	2.0e-26	113	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
650823592	399	32.25	34	399	12	367	5.0e-54	205	COG0387	Ca2+/H+ antiporter	368
650823593	129	28.45	4	119	12	127	3.0e-20	90.9	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
650823594	131	33.33	1	119	1	120	7.0e-23	99.4	COG0789	DNA-binding transcriptional regulator, MerR family	124
650823595	412	27.37	8	389	1	383	1.0e-43	171	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
650823599	150	41.1	15	148	5	149	4.0e-18	84.3	COG2165	Type II secretory pathway, pseudopilin PulG	149
650823602	204	21.54	1	188	4	184	3.0e-15	75	COG4795	Type II secretory pathway, component PulJ	194
650823603	310	29.26	20	301	5	308	2.0e-34	139	COG3156	Type II secretory pathway, component PulK	323
650823605	199	22.42	16	179	13	169	1.0e-08	53.5	COG3149	Type II secretory pathway, component PulM	181
650823607	792	29.68	100	743	30	561	2.0e-95	343	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
650823608	473	51.34	1	472	16	500	0.0e+00	542	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
650823609	402	42.04	1	402	1	397	6.0e-101	361	COG1459	Type II secretory pathway, component PulF	397
650823610	719	27.83	34	473	5	364	1.0e-34	142	COG3119	Arylsulfatase A or related enzyme	475
650823611	364	31.71	44	361	53	314	7.0e-37	148	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
650823615	235	41.67	6	229	4	229	7.0e-53	200	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650823616	485	26.36	157	483	18	336	2.0e-27	117	COG0642	Signal transduction histidine kinase	336
650823618	501	56.49	1	500	1	501	0.0e+00	594	COG3333	TctA family transporter	504
650823619	182	36.31	5	179	2	176	2.0e-30	125	COG0431	NAD(P)H-dependent FMN reductase	184
650823620	75	38.89	2	73	18	89	3.0e-15	73.3	COG1254	Acylphosphatase	92
650823621	141	29.73	1	141	5	151	1.0e-14	72.3	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
650823622	390	47.41	43	386	56	394	4.0e-98	351	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
650823623	339	50.89	1	337	1	300	3.0e-113	401	COG1023	6-phosphogluconate dehydrogenase (decarboxylating)	300
650823625	254	44.65	7	210	4	218	3.0e-35	142	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
650823626	465	41.79	9	457	4	433	7.0e-95	341	COG1030	Membrane-bound serine protease (ClpP class)	436
650823627	120	49.57	5	119	4	117	2.0e-32	130	COG3189	Uncharacterized conserved protein YeaO, DUF488 family	117
650823628	465	66.59	5	465	4	462	0.0e+00	752	COG0114	Fumarate hydratase class II	462
650823629	349	43.71	4	335	1	328	2.0e-99	356	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
650823630	515	38.2	25	501	3	470	1.0e-124	440	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650823631	381	53.72	1	375	1	376	2.0e-122	432	COG1929	Glycerate kinase	378
650823632	325	39.81	6	321	1	321	2.0e-81	296	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
650823633	618	28.45	56	612	69	617	1.0e-78	288	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
650823634	210	36.71	9	207	1	205	3.0e-27	114	COG0625	Glutathione S-transferase	211
650823635	233	58.55	1	232	3	236	4.0e-93	334	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650823636	255	55.34	2	254	1	250	1.0e-93	335	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650823637	408	45.48	79	404	4	312	1.0e-57	217	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
650823638	308	45.72	5	307	3	297	3.0e-53	202	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650823639	373	36.77	20	370	2	360	1.0e-63	236	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650823640	277	44.65	6	274	3	266	1.0e-61	230	COG0345	Pyrroline-5-carboxylate reductase	266
650823641	435	28.28	1	430	5	433	6.0e-48	185	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650823642	294	44.86	2	291	1	290	3.0e-57	215	COG1175	ABC-type sugar transport system, permease component	295
650823643	280	39.13	4	276	6	276	1.0e-56	213	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650823645	361	54.08	1	354	1	338	4.0e-122	431	COG3839	ABC-type sugar transport system, ATPase component	338
650823646	374	35.83	21	373	2	361	3.0e-63	236	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650823647	174	45.75	22	174	4	156	5.0e-44	170	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
650823648	316	34.67	1	298	1	289	5.0e-38	152	COG0583	DNA-binding transcriptional regulator, LysR family	297
650823649	699	50.44	13	692	8	677	0.0e+00	792	COG1200	RecG-like helicase	677
650823650	128	47.29	1	128	2	128	1.0e-28	118	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
650823651	258	32.09	1	255	2	266	5.0e-50	191	COG1018	Ferredoxin-NADP reductase	266
650823652	347	25.56	48	346	1	299	4.0e-40	159	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
650823653	555	33.09	7	555	4	537	3.0e-75	276	COG1178	ABC-type Fe3+ transport system, permease component	540
650823655	502	44.71	1	501	4	457	0.0e+00	484	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
650823656	349	43.84	4	349	11	357	5.0e-81	294	COG3852	Signal transduction histidine kinase, nitrogen specific	363
650823657	470	51.05	2	470	1	443	0.0e+00	517	COG0174	Glutamine synthetase	443
650823658	416	43.72	26	415	18	410	9.0e-108	383	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
650823659	197	51.53	1	195	4	193	3.0e-62	231	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
650823660	307	28.28	5	299	1	293	6.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
650823662	386	38.46	9	386	10	393	1.0e-84	307	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650823663	450	31.03	1	444	3	443	1.0e-76	280	COG2079	2-methylcitrate dehydratase PrpD	453
650823664	271	56.12	36	271	9	230	6.0e-72	264	COG0689	Ribonuclease PH	230
650823665	319	36.22	1	319	1	290	9.0e-60	223	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
650823667	361	27.58	1	358	8	354	4.0e-31	128	COG0628	Predicted PurR-regulated permease PerM	355
650823668	311	31.48	37	305	5	231	7.0e-33	134	COG0775	Nucleoside phosphorylase	234
650823669	427	24.62	36	415	30	388	7.0e-12	65.6	COG2807	Cyanate permease	395
650823670	306	29.77	8	301	4	292	2.0e-34	139	COG0583	DNA-binding transcriptional regulator, LysR family	297
650823671	356	47.47	1	355	1	347	1.0e-122	433	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
650823674	257	39.22	1	245	1	253	4.0e-52	198	COG3332	Uncharacterized conserved protein, contains NRDE domain	270
650823675	222	24.62	6	175	3	190	3.0e-12	65.7	COG0400	Predicted esterase	207
650823678	1039	36.15	3	1008	1	1041	0.0e+00	950	COG0587	DNA polymerase III, alpha subunit	1139
650823679	152	45.64	4	151	2	147	3.0e-26	111	COG1610	Uncharacterized conserved protein YqeY	148
650823681	359	41.53	1	347	3	356	1.0e-87	317	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
650823682	217	29.77	3	212	2	216	3.0e-34	138	COG0569	Trk K+ transport system, NAD-binding component	225
650823683	455	32.15	23	451	56	499	4.0e-59	222	COG0168	Trk-type K+ transport system, membrane component	499
650823686	789	38.25	13	579	7	564	6.0e-104	372	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
650823687	132	21.97	1	125	16	147	4.0e-03	34.2	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
650823688	128	37.72	1	114	1	114	8.0e-20	89.5	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
650823689	420	37.06	1	418	80	504	1.0e-60	227	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
650823691	98	39.53	6	91	1	86	3.0e-06	43.6	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
650823692	138	36.19	1	103	3	107	2.0e-19	88.4	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
650823693	467	24.68	159	459	34	327	2.0e-21	97.5	COG0642	Signal transduction histidine kinase	336
650823694	436	37.81	7	434	6	452	4.0e-99	355	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
650823697	675	22.73	45	278	1	223	2.0e-14	75.1	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
650823698	442	31.51	21	440	2	437	3.0e-53	202	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
650823702	312	26.98	20	271	5	241	3.0e-28	119	COG1462	Curli biogenesis system outer membrane secretion channel CsgG	252
650823705	245	25.33	4	228	3	207	2.0e-24	105	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
650823706	184	38.68	77	182	7	109	7.0e-22	97.3	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
650823707	151	40.14	6	150	1	147	1.0e-33	135	COG0822	NifU homolog involved in Fe-S cluster formation	150
650823708	417	55.53	18	412	10	405	0.0e+00	480	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
650823709	435	28.1	7	421	1	407	3.0e-70	259	COG0719	Fe-S cluster assembly scaffold protein SufB	412
650823710	256	60.87	1	252	3	251	2.0e-100	358	COG0396	Fe-S cluster assembly ATPase SufC	251
650823711	495	43.08	50	493	1	412	8.0e-122	430	COG0719	Fe-S cluster assembly scaffold protein SufB	412
650823712	164	29.63	2	135	1	134	3.0e-24	105	COG1959	DNA-binding transcriptional regulator, IscR family	150
650823714	592	60.4	91	584	1	495	0.0e+00	648	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
650823715	319	32.78	3	299	1	297	5.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
650823718	326	36.25	7	324	1	318	4.0e-64	238	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650823719	174	31.21	9	171	3	174	2.0e-18	85.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650823720	321	24.87	118	301	59	235	3.0e-12	66.2	COG5343	Anti-sigma-K factor RskA	240
650823721	461	49.65	174	457	2	262	4.0e-85	309	COG1760	L-serine deaminase	262
650823722	137	34.78	1	115	8	119	1.0e-16	79.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650823723	140	24.53	19	123	1	105	2.0e-12	65.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
650823724	106	47.31	6	98	1	93	1.0e-27	114	COG0776	Bacterial nucleoid DNA-binding protein	94
650823725	803	38.68	143	802	1	650	0.0e+00	559	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
650823726	340	52.52	5	337	6	335	1.0e-114	406	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
650823727	119	72.03	1	118	1	118	5.0e-39	152	COG0292	Ribosomal protein L20	118
650823728	62	61.29	1	62	4	65	8.0e-10	55.2	COG0291	Ribosomal protein L35	65
650823730	350	37.01	14	343	6	340	9.0e-86	310	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
650823731	505	51.72	15	500	1	485	0.0e+00	535	COG0606	Predicted ATPase with chaperone activity	490
650823732	92	39.73	8	77	16	88	3.0e-11	60	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
650823734	112	68.75	1	112	1	112	2.0e-42	163	COG0347	Nitrogen regulatory protein PII	112
650823735	408	55.64	1	407	1	403	4.0e-119	421	COG0004	Ammonia channel protein AmtB	409
650823736	585	46.86	18	573	3	555	0.0e+00	598	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
650823737	89	45.98	1	87	1	87	1.0e-19	87.9	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
650823738	135	27.93	1	109	1	107	4.0e-14	70.3	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
650823739	329	37.69	1	318	1	316	3.0e-60	226	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
650823740	163	66.67	1	156	21	176	7.0e-59	219	COG0290	Translation initiation factor IF-3	176
650823741	648	58.19	57	641	10	585	0.0e+00	779	COG0441	Threonyl-tRNA synthetase	589
650823744	674	25.81	47	673	83	718	2.0e-57	217	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
650823745	431	21.11	37	415	36	388	7.0e-12	65.6	COG2814	Predicted arabinose efflux permease, MFS family	394
650823746	705	34.9	21	696	5	675	0.0e+00	520	COG1770	Protease II	682
650823748	219	41.59	4	212	1	205	2.0e-53	202	COG0135	Phosphoribosylanthranilate isomerase	208
650823750	209	53.18	1	173	1	173	3.0e-53	201	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
650823751	267	50	2	249	5	252	7.0e-85	307	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
650823753	364	30.47	1	359	12	332	6.0e-80	291	COG0136	Aspartate-semialdehyde dehydrogenase	334
650823754	358	52.05	1	358	2	346	1.0e-120	426	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
650823755	216	53.81	1	210	1	189	1.0e-72	265	COG0066	3-isopropylmalate dehydratase small subunit	191
650823756	467	55.53	1	466	1	422	0.0e+00	618	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
650823759	352	56.15	2	352	1	357	0.0e+00	510	COG0082	Chorismate synthase	369
650823760	491	46.48	1	491	1	488	0.0e+00	549	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
650823761	130	48.7	13	125	19	131	5.0e-22	96.5	COG3308	Uncharacterized membrane protein	131
650823762	468	31.23	46	304	17	284	3.0e-42	166	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
650823763	153	34.75	7	121	1	116	3.0e-13	67.9	COG0517	CBS domain	117
650823764	334	35.67	12	304	12	301	6.0e-69	254	COG0042	tRNA-dihydrouridine synthase	323
650823766	433	36.36	12	425	23	434	4.0e-100	358	COG1257	Hydroxymethylglutaryl-CoA reductase	436
650823767	401	26.85	21	375	2	364	2.0e-48	186	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650823768	321	31.08	1	318	5	322	1.0e-53	204	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
650823770	196	24.47	7	193	13	200	3.0e-07	48.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650823771	606	33.78	10	606	15	608	0.0e+00	467	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
650823772	287	53.09	22	264	1	237	2.0e-82	299	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650823773	396	25.75	29	358	2	331	4.0e-34	139	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650823774	345	39.38	20	336	4	313	3.0e-42	166	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
650823775	293	35.69	2	292	1	297	1.0e-37	150	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650823776	276	51.19	6	257	3	250	1.0e-86	312	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650823779	282	32.72	62	278	89	305	3.0e-36	145	COG4965	Flp pilus assembly protein TadB	309
650823780	577	52.63	209	531	32	349	3.0e-103	369	COG4962	Pilus assembly protein, ATPase of CpaF family	355
650823781	474	33.67	20	399	27	407	1.0e-52	200	COG4964	Flp pilus assembly protein, secretin CpaC	455
650823782	326	29.52	7	222	4	227	1.0e-18	87.3	COG3745	Flp pilus assembly protein CpaB	276
650823787	252	38.01	36	252	9	219	8.0e-44	170	COG4122	Predicted O-methyltransferase YrrM	219
650823788	260	27.64	1	255	4	269	7.0e-35	141	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
650823789	194	41.15	3	193	5	191	2.0e-44	172	COG3709	Ribose 1,5-bisphosphokinase PhnN	192
650823790	381	61.01	5	381	1	377	0.0e+00	510	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
650823791	234	60.79	1	227	1	227	3.0e-89	321	COG4778	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL	235
650823792	256	77.56	3	256	5	258	1.0e-116	412	COG4107	ABC-type phosphonate transport system, ATPase component	258
650823793	290	75.09	8	288	6	286	0.0e+00	501	COG3627	Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase	291
650823794	365	72.73	1	351	1	351	0.0e+00	550	COG3626	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI	367
650823795	193	45.79	4	189	5	194	9.0e-50	189	COG3625	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH	196
650823796	156	53.38	13	155	4	151	2.0e-37	148	COG3624	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG	151
650823797	240	30.08	3	234	1	236	4.0e-38	151	COG2188	DNA-binding transcriptional regulator, GntR family	236
650823798	225	49.77	9	225	62	282	2.0e-60	225	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
650823799	334	37.16	3	286	1	291	2.0e-68	253	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
650823800	278	57.48	3	255	2	250	9.0e-86	310	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
650823803	234	43.52	21	233	56	265	5.0e-64	237	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
650823804	178	55.43	1	175	1	171	2.0e-52	198	COG0221	Inorganic pyrophosphatase	171
650823805	511	29.53	1	382	1	380	1.0e-49	191	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
650823806	432	25.42	6	419	2	389	2.0e-29	123	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
650823807	271	31.3	9	238	3	220	2.0e-26	113	COG1587	Uroporphyrinogen-III synthase	248
650823808	315	56.11	7	308	3	305	1.0e-108	386	COG0181	Porphobilinogen deaminase	307
650823810	237	25	10	233	17	254	2.0e-30	125	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
650823811	293	61.22	1	293	1	289	5.0e-109	387	COG0074	Succinyl-CoA synthetase, alpha subunit	293
650823812	386	57.47	1	386	1	385	0.0e+00	516	COG0045	Succinyl-CoA synthetase, beta subunit	387
650823814	764	61.4	434	762	2	328	1.0e-125	444	COG0620	Methionine synthase II (cobalamin-independent)	330
650823815	306	30.77	2	298	1	295	1.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
650823816	172	36.49	29	172	22	169	2.0e-24	105	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
650823817	355	67.38	11	289	6	279	3.0e-89	322	COG0468	RecA/RadA recombinase	279
650823818	229	43.23	1	221	1	228	4.0e-52	198	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650823819	499	29.74	156	497	2	334	5.0e-38	152	COG0642	Signal transduction histidine kinase	336
650823821	565	21.71	19	338	1	290	3.0e-08	54.1	COG2814	Predicted arabinose efflux permease, MFS family	394
650823822	299	44.52	1	298	1	301	1.0e-92	333	COG2974	DNA recombination-dependent growth factor C	303
650823823	430	41.43	87	401	7	314	2.0e-83	303	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
650823825	723	34.16	41	717	38	731	6.0e-102	365	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
650823826	2003	21.76	545	1991	291	1614	5.0e-88	320	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
650823828	333	28.96	3	324	71	402	6.0e-28	118	COG3464	Transposase	402
650823833	69	54.69	6	69	4	67	4.0e-22	96	COG1278	Cold shock protein, CspA family	67
650823836	168	37.66	1	154	1	147	5.0e-32	130	COG1959	DNA-binding transcriptional regulator, IscR family	150
650823839	262	54.65	1	254	5	262	1.0e-85	309	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
650823840	400	21.41	49	397	56	394	8.0e-07	48.7	COG2814	Predicted arabinose efflux permease, MFS family	394
650823841	124	32.71	14	120	23	126	8.0e-08	49.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
650823845	120	44.55	2	111	9	117	4.0e-15	73.3	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
650823846	633	53.65	19	633	16	627	0.0e+00	721	COG3158	K+ transporter	627
650823850	385	55.91	4	384	17	397	4.0e-99	355	COG3135	Predicted benzoate:H+ symporter BenE	402
650823851	254	58.06	5	252	4	251	2.0e-93	335	COG1540	Lactam utilization protein B (function unknown)	252
650823852	749	46.8	391	747	1	342	8.0e-97	348	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
650823854	622	43.34	1	410	26	423	7.0e-103	368	COG0358	DNA primase (bacterial type)	568
650823855	70	60.94	1	64	1	64	4.0e-07	46.8	COG0828	Ribosomal protein S21	67
650823856	180	36.08	7	163	1	150	1.0e-25	109	COG2236	Hypoxanthine phosphoribosyltransferase	192
650823857	443	57.71	15	441	2	429	0.0e+00	624	COG0104	Adenylosuccinate synthase	430
650823858	388	37.02	3	384	1	385	6.0e-66	244	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
650823859	302	29.79	3	279	2	278	2.0e-44	173	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
650823860	433	26.25	82	378	5	291	5.0e-45	175	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
650823861	365	53.43	1	350	4	353	2.0e-113	402	COG2262	50S ribosomal subunit-associated GTPase HflX	411
650823862	78	70.27	3	75	2	75	4.0e-24	102	COG1923	sRNA-binding regulator protein Hfq	77
650823863	361	39.83	5	359	2	354	4.0e-84	305	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
650823864	478	44.26	7	474	3	442	0.0e+00	527	COG1160	Predicted GTPases	444
650823865	385	23.69	9	360	6	348	9.0e-23	101	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
650823866	211	36.49	1	210	1	207	1.0e-34	139	COG2976	Putative negative regulator of RcsB-dependent stress response	207
650823867	429	46.17	6	426	2	425	0.0e+00	461	COG0124	Histidyl-tRNA synthetase	429
650823868	434	45.1	21	428	3	361	3.0e-125	442	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
650823870	386	50.27	7	368	2	348	5.0e-121	427	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
650823871	141	60	2	136	1	135	4.0e-54	203	COG0105	Nucleoside diphosphate kinase	135
650823872	950	49.84	13	949	1	875	0.0e+00	1149	COG0525	Valyl-tRNA synthetase	877
650823873	696	33.76	7	618	4	594	7.0e-88	318	COG1042	Acyl-CoA synthetase (NDP forming)	598
650823874	265	33.73	4	255	2	254	1.0e-39	156	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650823875	396	35.81	19	393	2	372	1.0e-70	260	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
650823876	327	40.51	9	324	4	317	1.0e-70	259	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650823878	191	49.47	1	190	60	239	4.0e-66	244	COG0336	tRNA G37 N-methylase TrmD	240
650823879	191	28.95	2	191	9	172	5.0e-32	130	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
650823880	84	59.74	1	77	1	76	8.0e-25	105	COG0228	Ribosomal protein S16	87
650823881	85	35.21	14	84	7	77	3.0e-13	66.8	COG0425	TusA-related sulfurtransferase	78
650823882	873	57.16	1	872	6	879	0.0e+00	1179	COG0013	Alanyl-tRNA synthetase	879
650823891	440	22.92	15	437	11	430	2.0e-33	137	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650823892	417	27.27	1	417	5	377	7.0e-39	155	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
650823893	344	30.74	102	332	7	222	4.0e-46	178	COG0543	NAD(P)H-flavin reductase	252
650823894	767	41.11	17	755	10	733	0.0e+00	704	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
650823895	640	44.43	1	638	14	632	0.0e+00	716	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
650823897	418	70.1	1	418	4	420	0.0e+00	690	COG1158	Transcription termination factor Rho	422
650823898	447	45.92	20	447	1	411	0.0e+00	512	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
650823900	925	39.25	9	922	49	953	0.0e+00	712	COG1391	Glutamine synthetase adenylyltransferase	963
650823901	226	59.11	15	216	3	204	2.0e-84	305	COG1636	Predicted ATPase, Adenine nucleotide alpha hydrolases (AANH) superfamily	204
650823902	864	55.44	5	862	1	784	0.0e+00	952	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
650823903	76	44.87	1	76	1	78	2.0e-12	64.2	COG2336	Antitoxin component of the MazEF toxin-antitoxin module	82
650823904	112	30.63	5	109	1	110	2.0e-14	70.8	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
650823905	225	33.02	1	214	1	214	7.0e-32	130	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
650823908	499	35.55	49	468	1	382	1.0e-78	287	COG0348	Polyferredoxin	386
650823909	307	32.54	88	208	4	126	7.0e-15	75	COG2010	Cytochrome c, mono- and diheme variants	150
650823910	57	21.15	1	52	7	58	7.0e-05	39	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
650823911	218	58.33	10	204	3	218	1.0e-80	292	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
650823912	494	71.73	5	482	2	482	0.0e+00	695	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
650823913	50	42.55	3	49	2	48	2.0e-08	51	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
650823915	441	75.98	1	430	1	433	0.0e+00	666	COG2224	Isocitrate lyase	433
650823916	295	46.46	22	145	5	130	2.0e-38	152	COG2904	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, N-terminal domain	137
650823917	430	20.71	1	414	10	429	6.0e-19	89.1	COG2271	Sugar phosphate permease	448
650823918	188	39.89	1	187	12	192	6.0e-23	100	COG0558	Phosphatidylglycerophosphate synthase	192
650823919	607	47.93	5	606	3	581	0.0e+00	613	COG0322	Excinuclease UvrABC, nuclease subunit	581
650823920	352	44.55	9	322	2	312	2.0e-76	279	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
650823921	151	36.92	11	139	2	126	2.0e-29	121	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
650823923	438	54.88	1	438	2	437	0.0e+00	526	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
650823924	158	26.09	20	153	3	139	1.0e-16	79.3	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
650823925	261	44.19	1	256	2	256	3.0e-54	205	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650823926	554	21.3	89	525	38	437	6.0e-30	125	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650823927	360	29.75	1	270	2	264	6.0e-41	162	COG1018	Ferredoxin-NADP reductase	266
650823928	169	34.65	8	105	12	111	1.0e-19	89.2	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
650823929	254	38.82	3	254	18	265	1.0e-57	216	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
650823930	95	58.1	1	95	5	109	4.0e-31	126	COG3460	1,2-phenylacetyl-CoA epoxidase, PaaB subunit	117
650823931	330	47.01	31	297	1	265	8.0e-92	330	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
650823932	290	35.04	2	255	13	260	2.0e-54	206	COG3327	DNA-binding transcriptional regulator PaaX (phenylacetic acid degradation)	291
650823933	169	62.72	1	169	13	181	2.0e-72	264	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
650823934	414	25.5	122	413	12	295	2.0e-21	97.7	COG0501	Zn-dependent protease with chaperone function	302
650823935	300	40.4	6	300	12	298	4.0e-74	271	COG1162	Putative ribosome biogenesis GTPase RsgA	301
650823936	248	19.58	83	216	17	155	2.0e-07	50	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
650823937	129	61.86	1	118	3	115	9.0e-36	142	COG0335	Ribosomal protein L19	115
650823939	213	37.11	4	191	3	193	8.0e-57	213	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
650823940	607	34.1	34	463	6	392	7.0e-62	232	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650823941	309	58.73	1	309	1	310	1.0e-84	306	COG2025	Electron transfer flavoprotein, alpha subunit	313
650823942	249	51.74	1	248	1	259	9.0e-71	260	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
650823943	307	45.54	1	307	2	312	4.0e-79	288	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
650823944	402	31.34	47	397	15	340	2.0e-59	223	COG2951	Membrane-bound lytic murein transglycosylase B	343
650823945	306	47.19	9	302	2	300	2.0e-97	349	COG0031	Cysteine synthase	300
650823947	331	27.73	1	331	2	314	3.0e-40	159	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650823949	417	32.52	7	415	5	387	2.0e-82	299	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
650823950	107	31.65	1	79	22	98	6.0e-08	49.1	COG5416	Uncharacterized integral membrane protein	98
650823951	103	52.7	4	77	20	93	2.0e-24	103	COG0776	Bacterial nucleoid DNA-binding protein	94
650823952	571	56.39	13	559	3	541	0.0e+00	594	COG0539	Ribosomal protein S1	541
650823953	226	51.83	9	224	5	222	2.0e-66	245	COG0283	Cytidylate kinase	222
650823954	441	41.31	17	439	15	425	4.0e-109	388	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
650823955	302	38.52	16	295	4	279	1.0e-58	220	COG0287	Prephenate dehydrogenase	279
650823956	379	44.78	19	377	6	353	2.0e-85	309	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
650823957	361	46.69	94	359	3	273	3.0e-91	328	COG0077	Prephenate dehydratase	279
650823958	375	54.52	1	375	4	365	3.0e-127	448	COG1932	Phosphoserine aminotransferase	365
650823959	864	56.47	1	840	17	804	0.0e+00	1036	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
650823960	192	36.32	1	190	3	190	1.0e-33	136	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
650823961	244	58.2	1	241	1	240	8.0e-89	319	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
650823962	226	38.91	1	218	3	220	2.0e-41	162	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
650823965	410	75.13	7	400	3	396	0.0e+00	524	COG3633	Na+/serine symporter	407
650823967	216	42.36	1	203	2	202	6.0e-56	210	COG1182	FMN-dependent NADH-azoreductase	202
650823968	444	42.6	6	382	49	433	2.0e-103	369	COG0513	Superfamily II DNA and RNA helicase	513
650823969	224	57.73	27	220	1	193	5.0e-70	257	COG0807	GTP cyclohydrolase II	193
650823970	234	51.05	1	232	1	237	1.0e-79	289	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650823971	612	42.57	359	605	2	250	2.0e-66	247	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650823972	291	39.73	2	291	1	296	3.0e-47	182	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650823973	448	26.84	47	423	2	366	5.0e-43	169	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650823981	278	42.45	2	277	23	299	2.0e-71	262	COG3285	Eukaryotic-type DNA primase	299
650823985	623	46.35	11	613	26	638	3.0e-122	432	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
650823986	311	32.04	6	308	8	316	2.0e-51	196	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
650823987	642	22.88	58	400	42	387	2.0e-34	141	COG1680	CubicO group peptidase, beta-lactamase class C family	390
650823995	458	34.58	16	458	1	435	8.0e-102	364	COG0015	Adenylosuccinate lyase	438
650823996	229	34.33	26	221	1	198	2.0e-33	136	COG0625	Glutathione S-transferase	211
650823997	269	30.55	1	269	2	257	7.0e-11	61.6	COG0730	Uncharacterized membrane protein YfcA	258
650823998	379	55.22	18	378	5	352	1.0e-129	456	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
650823999	412	30.17	16	407	2	385	2.0e-60	226	COG0247	Fe-S oxidoreductase	388
650824000	365	23.88	7	365	43	459	3.0e-34	139	COG0277	FAD/FMN-containing dehydrogenase	459
650824001	497	39.39	22	473	1	459	3.0e-94	339	COG0277	FAD/FMN-containing dehydrogenase	459
650824002	470	38.9	27	468	8	457	1.0e-90	327	COG0277	FAD/FMN-containing dehydrogenase	459
650824003	364	67.81	1	350	1	351	0.0e+00	568	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
650824004	301	26.98	21	293	3	275	3.0e-25	109	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650824005	223	39.17	3	219	11	222	3.0e-46	178	COG0765	ABC-type amino acid transport system, permease component	222
650824006	230	42.79	13	226	8	222	3.0e-46	178	COG0765	ABC-type amino acid transport system, permease component	222
650824007	279	55.42	24	272	1	237	5.0e-99	354	COG1126	ABC-type polar amino acid transport system, ATPase component	240
650824008	306	15.85	36	260	10	222	2.0e-10	60	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
650824009	131	27.78	11	116	14	117	7.0e-05	39.6	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
650824010	436	36.53	1	419	16	447	3.0e-108	385	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
650824012	182	37.17	22	134	1	113	3.0e-12	65	COG1846	DNA-binding transcriptional regulator, MarR family	126
650824013	485	42.24	25	484	1	454	2.0e-120	425	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
650824014	258	38.82	7	256	17	262	3.0e-56	211	COG0388	Predicted amidohydrolase	274
650824015	124	25.81	2	123	16	128	3.0e-09	54.2	COG2916	DNA-binding protein H-NS	128
650824017	897	35.35	1	890	4	859	0.0e+00	575	COG0308	Aminopeptidase N	859
650824018	336	54.52	3	334	1	323	3.0e-125	441	COG0158	Fructose-1,6-bisphosphatase	326
650824019	328	45.09	6	326	2	325	2.0e-75	276	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
650824020	288	25.35	13	287	15	293	3.0e-09	55.9	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
650824021	355	47.31	5	355	4	348	6.0e-122	430	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
650824022	516	28.1	17	437	3	461	1.0e-33	138	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
650824023	247	57.44	1	241	1	241	6.0e-94	337	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
650824024	429	55.76	1	429	1	428	0.0e+00	575	COG0151	Phosphoribosylamine-glycine ligase	428
650824025	302	61.74	7	302	9	303	1.0e-121	429	COG0408	Coproporphyrinogen III oxidase	303
650824026	200	38	1	195	1	195	4.0e-40	158	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
650824027	131	44.95	1	109	1	109	2.0e-32	131	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
650824028	156	43.87	1	155	1	155	3.0e-51	194	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
650824029	479	48.12	1	478	2	477	0.0e+00	554	COG0469	Pyruvate kinase	477
650824030	206	46.27	6	205	5	187	2.0e-54	205	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
650824031	213	31.6	2	208	3	204	2.0e-40	159	COG0288	Carbonic anhydrase	207
650824032	396	25	41	396	16	352	4.0e-31	129	COG0628	Predicted PurR-regulated permease PerM	355
650824033	353	26.71	10	345	17	342	5.0e-30	125	COG0628	Predicted PurR-regulated permease PerM	355
650824037	160	46.67	1	150	7	156	2.0e-44	171	COG1607	Acyl-CoA hydrolase	157
650824038	402	45.43	9	401	6	396	2.0e-112	399	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650824039	259	37.84	1	256	3	257	5.0e-43	167	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650824040	427	49.87	49	425	2	378	7.0e-89	321	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650824041	180	32.7	12	169	4	161	7.0e-19	87.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
650824042	340	40.48	17	340	1	331	2.0e-80	292	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650824043	401	41.16	14	389	8	381	5.0e-95	341	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
650824044	245	39.27	7	224	5	222	4.0e-37	148	COG1802	DNA-binding transcriptional regulator, GntR family	230
650824045	1002	31.57	28	532	8	458	3.0e-65	244	COG0277	FAD/FMN-containing dehydrogenase	459
650824046	224	43.4	4	210	15	225	1.0e-38	153	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
650824047	432	52.45	46	432	1	379	8.0e-89	320	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650824049	327	36.53	9	325	12	332	9.0e-69	254	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650824050	490	43.4	16	490	1	467	1.0e-120	427	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650824051	391	44.53	10	384	4	374	4.0e-112	398	COG1454	Alcohol dehydrogenase, class IV	377
650824052	351	39.83	2	345	3	346	6.0e-92	331	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
650824053	157	44.16	1	154	60	210	6.0e-35	140	COG0684	Regulator of RNase E activity RraA	210
650824054	300	34.04	5	282	4	279	5.0e-35	141	COG0583	DNA-binding transcriptional regulator, LysR family	297
650824057	313	38.24	6	239	4	236	3.0e-55	209	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
650824058	433	26.93	22	368	1	338	8.0e-31	128	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650824059	374	44	1	374	1	366	2.0e-114	406	COG1062	Zn-dependent alcohol dehydrogenase	366
650824060	250	41.34	4	249	3	251	5.0e-51	194	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650824061	478	43.76	2	472	1	465	1.0e-128	453	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650824062	221	40.83	1	218	3	218	2.0e-49	188	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650824063	246	36.8	1	246	1	250	2.0e-61	228	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650824064	307	30.55	2	306	7	313	8.0e-25	108	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
650824065	301	32.2	1	293	1	290	1.0e-36	147	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650824066	188	28.45	55	168	7	117	2.0e-11	62.3	COG0727	Fe-S-cluster containining protein	132
650824067	233	31.75	21	226	2	200	1.0e-33	136	COG0625	Glutathione S-transferase	211
650824068	523	22.65	8	523	1	531	1.0e-60	227	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
650824069	334	34.06	4	326	1	318	1.0e-57	216	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650824070	443	22.73	11	350	1	300	3.0e-32	133	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
650824071	175	29.01	6	166	5	155	1.0e-16	79.6	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
650824072	476	45.99	2	474	1	467	1.0e-130	460	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650824073	541	41.13	1	531	33	574	0.0e+00	542	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
650824074	332	43.34	4	321	3	324	2.0e-90	325	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
650824076	108	37.74	1	105	1	102	5.0e-10	56.2	COG0633	Ferredoxin	102
650824077	383	27.6	2	332	18	352	4.0e-43	168	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
650824078	252	41.07	18	237	11	231	9.0e-37	147	COG2186	DNA-binding transcriptional regulator, FadR family	241
650824079	330	35.09	3	324	1	317	9.0e-57	213	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650824081	331	38.71	19	328	12	317	8.0e-67	247	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650824082	515	25.7	1	515	2	530	1.0e-79	291	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
650824083	453	43.68	3	449	1	444	0.0e+00	517	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
650824084	289	32.3	4	289	1	288	1.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
650824086	374	36.46	2	369	1	368	1.0e-68	253	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
650824087	303	31.62	5	291	3	286	2.0e-44	172	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
650824088	1223	53.26	703	1221	1	522	0.0e+00	676	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
650824089	292	41.13	17	292	5	276	2.0e-63	236	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
650824092	484	23.94	3	484	1	479	8.0e-50	191	COG5339	Uncharacterized conserved protein YdgA, DUF945 family	479
650824093	199	43.15	1	196	6	201	2.0e-43	168	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
650824094	215	34.58	1	210	1	206	3.0e-32	131	COG0625	Glutathione S-transferase	211
650824095	298	67.27	2	278	17	294	3.0e-111	394	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
650824096	141	35.46	2	141	10	141	2.0e-26	111	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
650824097	225	48.62	8	225	7	224	6.0e-62	230	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
650824099	88	40.7	1	85	1	75	4.0e-15	73	COG0254	Ribosomal protein L31	75
650824100	584	19.76	17	506	4	457	3.0e-13	70.5	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
650824101	469	28.67	11	466	13	450	7.0e-50	191	COG0534	Na+-driven multidrug efflux pump	455
650824102	421	52.43	1	388	2	383	8.0e-130	457	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
650824103	283	50.35	1	283	2	284	2.0e-82	299	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
650824104	355	30.93	21	351	2	302	1.0e-49	190	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
650824105	418	48.75	108	388	10	280	2.0e-84	306	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
650824107	406	17.66	40	404	37	394	5.0e-16	79.1	COG2814	Predicted arabinose efflux permease, MFS family	394
650824109	66	72.31	1	64	13	77	3.0e-17	80.3	COG0227	Ribosomal protein L28	77
650824110	56	58	5	54	1	50	3.0e-09	53.3	COG0267	Ribosomal protein L33	50
650824111	885	46.34	1	884	1	813	0.0e+00	966	COG0495	Leucyl-tRNA synthetase	814
650824112	230	30.38	22	175	7	159	3.0e-15	75.3	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
650824113	350	30.56	10	346	6	333	9.0e-50	190	COG1466	DNA polymerase III, delta subunit	334
650824114	430	56.01	15	429	1	416	0.0e+00	560	COG0014	Gamma-glutamyl phosphate reductase	417
650824115	138	51.06	1	137	8	148	1.0e-35	142	COG1981	Uncharacterized membrane protein	149
650824116	478	37.67	99	470	3	378	3.0e-97	349	COG0116	23S rRNA G2445 N2-methylase RlmL	381
650824118	170	21.43	1	167	6	172	5.0e-05	40.9	COG1714	Uncharacterized membrane protein YckC, RDD family	172
650824119	450	25.98	13	442	1	419	8.0e-71	261	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
650824120	307	40.6	1	291	3	286	7.0e-69	254	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
650824123	428	66.04	1	427	1	423	0.0e+00	645	COG0148	Enolase	423
650824124	147	31.15	15	135	5	126	1.0e-12	65.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
650824125	537	20.34	21	432	11	362	3.0e-13	70.2	COG2814	Predicted arabinose efflux permease, MFS family	394
650824126	280	64	1	275	5	273	2.0e-121	428	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
650824127	550	60.88	2	546	1	533	0.0e+00	868	COG0504	CTP synthase (UTP-ammonia lyase)	533
650824128	597	28.93	177	552	14	381	2.0e-55	211	COG0006	Xaa-Pro aminopeptidase	384
650824129	217	62.44	3	214	6	214	8.0e-78	283	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
650824130	235	60.91	1	220	1	219	2.0e-84	305	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
650824131	146	30.53	20	146	10	137	5.0e-22	96.9	COG0824	Acyl-CoA thioesterase FadM	137
650824132	548	31.29	6	461	1	396	6.0e-71	261	COG0644	Dehydrogenase (flavoprotein)	396
650824133	301	22.45	9	296	7	292	2.0e-09	56.7	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
650824134	659	43.78	75	645	1	528	0.0e+00	640	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
650824135	443	23.7	27	433	12	432	8.0e-49	188	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
650824136	106	51.4	1	104	31	137	1.0e-22	98.4	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
650824138	130	33.67	5	102	1	94	2.0e-15	74.6	COG4378	Uncharacterized protein	103
650824139	317	29.51	1	303	1	294	4.0e-32	132	COG0583	DNA-binding transcriptional regulator, LysR family	297
650824140	497	39.09	9	486	3	472	1.0e-115	410	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650824141	403	25.27	17	375	1	363	3.0e-39	156	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650824143	306	26.6	2	289	1	292	2.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
650824144	371	31.68	1	359	1	363	2.0e-41	163	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
650824145	499	48.32	1	499	1	484	0.0e+00	504	COG0260	Leucyl aminopeptidase	485
650824146	143	29.45	1	143	1	142	1.0e-18	85.7	COG2927	DNA polymerase III, chi subunit	144
650824147	235	39.19	16	234	13	233	8.0e-28	117	COG0670	Integral membrane protein, interacts with FtsH	233
650824148	307	35.19	2	288	3	285	2.0e-53	203	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
650824151	295	46.13	2	295	1	296	2.0e-93	335	COG1159	GTPase Era, involved in 16S rRNA processing	298
650824152	252	50.88	1	220	5	228	1.0e-63	236	COG0571	dsRNA-specific ribonuclease	235
650824153	295	29.56	72	181	8	166	6.0e-14	71.6	COG0681	Signal peptidase I	166
650824154	597	69.06	1	597	6	603	0.0e+00	1035	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
650824155	496	38.02	14	392	1	347	3.0e-68	253	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
650824156	333	23.84	11	329	2	318	1.0e-42	167	COG3026	Negative regulator of sigma E activity	320
650824157	166	27.1	20	141	10	162	1.0e-06	46.6	COG3073	Negative regulator of sigma E activity	213
650824158	199	35.64	7	194	2	182	7.0e-33	133	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650824160	409	56.42	1	409	1	411	0.0e+00	509	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
650824161	79	65.38	1	78	3	80	1.0e-11	61.5	COG0236	Acyl carrier protein	80
650824162	247	46.61	6	245	3	250	1.0e-43	170	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650824163	311	52.43	1	307	2	310	6.0e-93	334	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
650824164	324	55.35	1	324	1	322	8.0e-109	387	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
650824165	360	51.79	6	340	2	337	2.0e-114	405	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
650824166	60	42.11	1	56	1	57	6.0e-11	59.1	COG0333	Ribosomal protein L32	57
650824168	192	40.31	1	189	3	192	2.0e-50	191	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
650824169	239	30.77	1	234	1	222	1.0e-40	159	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
650824170	257	42.31	7	256	2	254	2.0e-65	242	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
650824171	212	40.61	15	211	4	198	9.0e-37	146	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
650824172	287	38.15	2	260	17	271	9.0e-55	207	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
650824175	217	35.94	1	213	1	217	5.0e-43	168	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
650824176	322	39.31	23	309	5	289	5.0e-68	251	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
650824178	962	50.81	1	490	1	487	0.0e+00	522	COG1530	Ribonuclease G or E	487
650824179	291	58.22	1	291	1	292	3.0e-117	414	COG0777	Acetyl-CoA carboxylase beta subunit	294
650824180	282	46.15	6	250	2	248	2.0e-74	272	COG0159	Tryptophan synthase alpha chain	265
650824181	354	70.74	1	352	42	392	0.0e+00	628	COG0133	Tryptophan synthase beta chain	396
650824183	770	45.07	31	769	11	699	0.0e+00	707	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
650824185	117	30.33	1	116	7	128	1.0e-22	98.1	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
650824186	413	36.27	23	413	9	379	4.0e-89	322	COG1488	Nicotinic acid phosphoribosyltransferase	405
650824187	107	37.88	4	65	5	68	4.0e-08	49.8	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
650824189	408	56.65	1	406	1	406	0.0e+00	583	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
650824191	210	55.71	1	210	1	210	3.0e-83	301	COG0177	Endonuclease III	211
650824192	263	46.4	9	254	1	250	4.0e-79	287	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650824193	236	47.26	2	236	1	237	3.0e-75	274	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650824194	403	22.47	23	379	3	366	1.0e-38	154	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650824195	295	40.14	7	294	1	293	7.0e-48	184	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650824196	323	36.74	5	314	9	308	1.0e-43	170	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
650824198	258	53.11	9	248	2	237	1.0e-82	300	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650824199	617	52.38	343	591	2	250	6.0e-86	312	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650824200	345	32.76	1	345	1	296	2.0e-34	139	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650824201	389	32.11	18	388	1	365	2.0e-42	166	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650824202	131	59.23	3	131	1	130	4.0e-58	216	COG0229	Peptide methionine sulfoxide reductase MsrB	140
650824203	194	44.2	3	183	2	180	2.0e-43	168	COG2917	Intracellular septation protein A	180
650824204	87	41.67	1	84	1	82	1.0e-14	71.5	COG0271	Stress-induced morphogen (activity unknown)	90
650824205	258	25	27	258	66	299	2.0e-07	50.1	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
650824206	698	56.56	11	696	7	667	0.0e+00	906	COG0272	NAD-dependent DNA ligase	667
650824207	340	16.62	1	318	1	318	5.0e-03	35.8	COG3115	Cell division protein ZipA, interacts with FtsZ	324
650824208	1174	33.19	1	1172	1	1163	0.0e+00	570	COG1196	Chromosome segregation ATPase	1163
650824210	286	42.13	91	280	5	200	1.0e-36	147	COG1573	Uracil-DNA glycosylase	202
650824211	381	31.25	9	216	36	218	8.0e-28	118	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
650824212	244	46.78	11	242	2	229	2.0e-65	242	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650824213	480	27.54	176	470	39	334	7.0e-33	135	COG0642	Signal transduction histidine kinase	336
650824214	182	37.57	1	182	2	181	9.0e-46	176	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
650824215	160	62.99	5	158	1	154	5.0e-59	220	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
650824216	263	34.85	5	263	1	226	2.0e-44	172	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
650824217	1158	49.91	22	1157	3	1133	0.0e+00	1343	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
650824218	283	50	73	280	6	212	7.0e-53	200	COG0560	Phosphoserine phosphatase	212
650824219	825	26.28	25	792	50	805	7.0e-91	328	COG3264	Small-conductance mechanosensitive channel	835
650824220	493	44.65	3	488	1	472	6.0e-96	344	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
650824221	495	49.9	4	495	1	491	0.0e+00	521	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
650824222	666	44.75	7	660	1	606	0.0e+00	488	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
650824223	102	61	3	102	2	100	2.0e-21	94	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
650824224	212	38.32	1	167	1	166	6.0e-22	97.6	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
650824225	162	43.98	2	162	1	161	6.0e-43	166	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
650824226	357	48.39	14	354	3	332	2.0e-95	342	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
650824227	777	38.9	1	736	1	693	0.0e+00	593	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
650824228	455	61.85	28	448	5	424	0.0e+00	636	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
650824229	164	38.99	3	161	5	160	1.0e-42	165	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
650824230	418	59.33	1	418	9	398	0.0e+00	610	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
650824231	203	48.85	11	184	14	171	2.0e-45	175	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
650824232	158	64.74	3	158	13	168	7.0e-74	269	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
650824233	119	52.94	1	119	3	121	2.0e-31	127	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
650824234	361	28.34	1	361	1	354	6.0e-38	151	COG3203	Outer membrane protein (porin)	354
650824240	106	29.47	7	98	9	101	3.0e-07	46.8	COG3702	Type IV secretory pathway, VirB3 components	105
650824241	814	34.78	1	801	4	788	0.0e+00	519	COG3451	Type IV secretory pathway, VirB4 component	796
650824246	228	31.34	8	222	16	229	3.0e-34	138	COG3736	Type IV secretory pathway, component VirB8	239
650824247	295	30.71	5	268	6	262	7.0e-37	147	COG3504	Type IV secretory pathway, VirB9 components	265
650824248	375	31.51	87	374	50	360	1.0e-47	184	COG2948	Type IV secretory pathway, VirB10 components	360
650824249	339	32.23	30	323	23	294	2.0e-46	180	COG0630	Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase	312
650824265	673	47.46	6	673	69	711	0.0e+00	691	COG2217	Cation transport ATPase	713
650824266	303	27.03	1	292	1	292	3.0e-27	115	COG0583	DNA-binding transcriptional regulator, LysR family	297
650824267	412	32.99	13	398	5	394	3.0e-89	322	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
650824268	299	27.14	1	274	1	270	2.0e-35	143	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650824270	196	42.35	1	196	33	221	4.0e-41	161	COG0765	ABC-type amino acid transport system, permease component	222
650824271	244	59.92	1	242	2	240	1.0e-105	375	COG1126	ABC-type polar amino acid transport system, ATPase component	240
650824272	138	45.76	3	119	7	122	2.0e-33	134	COG3019	Uncharacterized conserved protein	149
650824274	169	36.2	11	169	3	157	5.0e-22	97.4	COG4454	Uncharacterized copper-binding protein, cupredoxin-like subfamily	158
650824275	405	38.65	80	405	40	321	1.0e-68	253	COG3667	Uncharacterized protein involved in copper resistance	321
650824277	175	50.57	1	173	13	188	2.0e-36	145	COG1971	Putative Mn2+ efflux pump MntP	190
650824281	66	32.31	1	62	3	67	7.0e-06	42.3	COG2608	Copper chaperone CopZ	71
650824284	227	44.05	1	222	1	226	5.0e-56	210	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650824285	471	30.54	140	469	9	333	1.0e-38	154	COG0642	Signal transduction histidine kinase	336
650824286	111	27.27	1	108	23	132	7.0e-09	52.4	COG3335	Transposase	132
650824287	134	30.43	1	113	2	116	2.0e-06	44.9	COG3415	Transposase	138
650824290	202	24.75	1	196	8	200	3.0e-16	78.5	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
650824291	205	28.33	61	180	41	149	4.0e-09	55	COG2010	Cytochrome c, mono- and diheme variants	150
650824293	549	31.25	85	545	3	482	4.0e-118	418	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
650824294	523	36.58	24	511	21	518	4.0e-86	312	COG0815	Apolipoprotein N-acyltransferase	518
650824296	766	39.89	40	743	4	710	0.0e+00	641	COG2217	Cation transport ATPase	713
650824303	205	40.98	2	183	40	220	2.0e-18	85.7	COG0785	Cytochrome c biogenesis protein CcdA	220
650824304	167	27.56	11	136	2	127	2.0e-13	69.2	COG0526	Thiol-disulfide isomerase or thioredoxin	127
650824305	285	30.9	1	280	1	281	8.0e-26	111	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
650824306	151	40.91	1	144	1	153	3.0e-33	134	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
650824307	174	23.44	28	152	2	127	8.0e-09	53.4	COG0526	Thiol-disulfide isomerase or thioredoxin	127
650824308	653	56.64	1	643	1	648	0.0e+00	632	COG1138	Cytochrome c biogenesis factor	648
650824309	148	51.09	2	138	3	139	2.0e-42	164	COG2332	Cytochrome c-type biogenesis protein CcmE	153
650824310	60	42.31	1	52	1	52	2.0e-06	44.5	COG3114	Heme exporter protein D	67
650824311	210	39.11	2	202	71	272	2.0e-30	125	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
650824312	206	53.4	1	206	16	221	7.0e-37	147	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
650824313	205	48.47	1	196	1	195	1.0e-50	192	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
650824319	160	48.68	7	82	4	78	3.0e-15	74.9	COG1314	Preprotein translocase subunit SecG	86
650824320	233	48.31	1	233	12	246	1.0e-67	249	COG0149	Triosephosphate isomerase	251
650824321	325	43.64	1	325	1	326	4.0e-78	284	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
650824322	649	59.46	16	649	22	654	0.0e+00	855	COG2015	Alkyl sulfatase BDS1 and related hydrolases, metallo-beta-lactamase superfamily	655
650824324	844	24.21	264	649	4	403	1.0e-17	86.1	COG4262	Predicted spermidine synthase with an N-terminal membrane domain	508
650824325	541	33.62	41	472	3	459	2.0e-79	290	COG3119	Arylsulfatase A or related enzyme	475
650824328	510	23.64	28	265	27	252	2.0e-06	47.6	COG1240	Mg-chelatase subunit ChlD	261
650824332	322	41.16	1	321	9	328	1.0e-59	223	COG0714	MoxR-like ATPase	329
650824333	381	29.92	1	362	6	310	3.0e-42	166	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
650824334	325	23.38	20	325	16	304	4.0e-25	108	COG4313	Uncharacterized conserved protein	304
650824335	89	19.3	3	88	14	127	1.0e-03	35.4	COG2916	DNA-binding protein H-NS	128
650824342	443	23.67	180	442	36	312	4.0e-09	56.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
650824344	506	22.49	62	474	47	451	1.0e-18	88.3	COG1538	Outer membrane protein TolC	457
650824348	232	42.08	1	230	2	241	3.0e-45	175	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
650824349	571	26.69	6	564	1	540	2.0e-56	214	COG2985	Uncharacterized membrane protein YbjL, putative transporter	544
650824354	102	44.76	1	101	10	114	1.0e-26	111	COG4744	Uncharacterized protein	121
650824355	178	19.08	1	170	32	201	2.0e-11	62.3	COG0811	Biopolymer transport protein ExbB/TolQ	216
650824356	1328	32.68	69	1273	59	1308	0.0e+00	821	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
650824357	659	35.43	11	659	13	699	0.0e+00	501	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
650824358	747	43.54	8	747	20	750	0.0e+00	727	COG4774	Outer membrane receptor for monomeric catechols	750
650824359	715	62.55	1	697	1	690	0.0e+00	992	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
650824360	89	56.18	1	89	1	89	4.0e-27	112	COG0184	Ribosomal protein S15P/S13E	89
650824362	300	39.83	9	241	4	233	6.0e-51	194	COG1183	Phosphatidylserine synthase	234
650824363	223	43.24	1	215	18	238	3.0e-51	195	COG0688	Phosphatidylserine decarboxylase	239
650824364	338	66.07	1	336	3	338	0.0e+00	542	COG0059	Ketol-acid reductoisomerase	338
650824365	163	57.14	1	161	3	163	7.0e-49	186	COG0440	Acetolactate synthase, small subunit	163
650824366	573	47.97	2	566	1	549	0.0e+00	643	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
650824367	238	24.52	45	199	16	169	5.0e-06	45	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650824368	233	50.42	1	233	2	237	2.0e-78	285	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650824369	256	46.99	2	248	1	249	1.0e-78	286	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650824370	314	34.41	1	305	1	307	8.0e-41	161	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
650824371	285	40	3	281	10	292	6.0e-41	161	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650824372	406	35.14	21	365	1	344	1.0e-51	197	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650824373	543	35.13	19	543	11	531	4.0e-114	405	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650824375	342	26.25	5	316	12	309	4.0e-25	108	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
650824376	398	33.83	1	394	1	393	4.0e-68	252	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650824377	255	40.78	5	251	1	251	2.0e-42	166	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650824378	744	18.86	7	683	1	626	5.0e-23	103	COG1289	Uncharacterized membrane protein YccC	674
650824379	263	52.11	1	261	1	252	1.0e-76	279	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
650824380	260	37.4	1	258	2	251	2.0e-42	166	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650824383	333	28.96	3	324	71	402	6.0e-28	118	COG3464	Transposase	402
650824385	624	44.62	29	610	13	633	0.0e+00	596	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
650824387	262	38.31	3	257	1	250	6.0e-32	131	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650824388	450	54.44	1	446	1	425	0.0e+00	547	COG0172	Seryl-tRNA synthetase	429
650824389	443	56.43	3	442	1	436	0.0e+00	567	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
650824390	211	33.33	10	211	10	211	2.0e-34	138	COG2834	Outer membrane lipoprotein-sorting protein	211
650824392	319	49.53	5	319	2	305	2.0e-92	332	COG0492	Thioredoxin reductase	305
650824393	181	38.41	1	164	19	178	4.0e-27	114	COG2840	DNA-nicking endonuclease, Smr domain	184
650824394	365	51.46	1	341	1	333	2.0e-94	339	COG2603	tRNA 2-selenouridine synthase SelU, contains rhodanese domain	334
650824395	418	65.61	11	418	2	406	0.0e+00	612	COG0538	Isocitrate dehydrogenase	407
650824397	120	40.87	1	115	1	103	8.0e-15	72.7	COG2863	Cytochrome c553	121
650824398	117	39.64	7	117	1	101	6.0e-14	69.6	COG2863	Cytochrome c553	121
650824399	305	22.04	11	305	2	300	8.0e-35	141	COG0714	MoxR-like ATPase	329
650824400	206	29.05	21	194	10	187	5.0e-17	81.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650824401	390	60.46	1	390	1	392	0.0e+00	498	COG3825	Uncharacterized conserved protein,  contains von Willebrand factor type A (vWA) domain	393
650824402	924	27.78	46	447	16	424	9.0e-55	209	COG0612	Predicted Zn-dependent peptidase	438
650824403	374	63.3	1	374	1	370	0.0e+00	503	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
650824404	638	60.46	1	606	4	579	0.0e+00	663	COG0443	Molecular chaperone DnaK (HSP70)	579
650824405	200	38.22	11	197	7	193	3.0e-32	131	COG0576	Molecular chaperone GrpE (heat shock protein)	193
650824406	377	39.51	53	375	4	320	3.0e-94	338	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
650824407	335	40.06	1	331	4	341	1.0e-80	293	COG1420	Transcriptional regulator of heat shock response	346
650824408	299	41.67	4	290	1	281	2.0e-64	239	COG0061	NAD kinase	281
650824409	551	44.24	1	551	1	556	0.0e+00	527	COG0497	DNA repair ATPase RecN	557
650824410	141	48.91	5	141	10	145	1.0e-35	142	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
650824411	178	30.43	1	108	3	117	3.0e-20	91.6	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
650824412	263	54.75	1	261	3	264	2.0e-87	315	COG0289	Dihydrodipicolinate reductase	266
650824413	366	32.34	33	366	6	287	7.0e-66	244	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
650824415	280	24.25	1	268	30	292	2.0e-04	40.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
650824418	269	42.51	1	240	20	264	7.0e-63	233	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
650824421	280	25.12	41	253	3	214	3.0e-33	135	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
650824422	301	29.66	11	295	1	287	5.0e-33	135	COG0583	DNA-binding transcriptional regulator, LysR family	297
650824423	360	55.11	1	352	1	338	8.0e-128	450	COG3839	ABC-type sugar transport system, ATPase component	338
650824424	439	20.37	26	438	12	431	3.0e-26	113	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650824425	300	40	4	297	2	295	2.0e-54	206	COG1175	ABC-type sugar transport system, permease component	295
650824426	301	41.42	35	300	14	281	4.0e-58	218	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650824427	260	39.83	11	242	4	237	3.0e-38	152	COG2186	DNA-binding transcriptional regulator, FadR family	241
650824428	324	23.62	1	320	1	307	9.0e-37	147	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650824429	428	44.84	3	427	1	412	4.0e-97	348	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
650824430	210	36.57	1	210	3	213	7.0e-41	160	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
650824431	257	58.2	1	256	1	256	1.0e-104	373	COG3622	Hydroxypyruvate isomerase	260
650824432	314	38.68	4	289	1	285	2.0e-62	232	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
650824433	295	50.7	2	285	1	286	3.0e-86	311	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
650824434	141	28.36	1	128	5	132	9.0e-12	63	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
650824435	145	34.48	1	133	8	151	2.0e-27	115	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
650824436	213	47.06	27	209	9	194	2.0e-65	242	COG4764	Uncharacterized protein	197
650824438	569	55.24	3	557	2	535	0.0e+00	666	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
650824439	277	49.28	1	276	11	288	2.0e-62	232	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
650824440	329	51.58	12	327	5	314	4.0e-85	308	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
650824441	541	34.06	11	541	4	555	1.0e-88	321	COG0747	ABC-type transport system, periplasmic component	556
650824442	309	35.53	3	306	2	302	4.0e-59	221	COG1893	Ketopantoate reductase	307
650824444	402	38.17	23	402	36	420	1.0e-89	323	COG1169	Isochorismate synthase EntC	423
650824445	324	35.56	7	321	5	317	3.0e-58	219	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650824446	127	53.76	4	96	8	100	5.0e-20	90	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
650824448	252	34.77	1	247	4	248	6.0e-41	161	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650824449	519	31.44	39	492	35	432	2.0e-60	227	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
650824452	216	47.93	1	216	6	222	1.0e-48	186	COG2011	ABC-type methionine transport system, permease component	222
650824454	150	35.21	1	136	4	145	2.0e-22	98.2	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
650824455	250	51.53	12	238	2	221	5.0e-70	257	COG2360	Leu/Phe-tRNA-protein transferase	221
650824456	242	42.86	12	236	10	240	2.0e-68	252	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
650824457	346	44.52	51	346	3	290	9.0e-82	297	COG0167	Dihydroorotate dehydrogenase	310
650824460	326	37.5	7	325	4	319	8.0e-74	270	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650824461	270	41.3	25	266	1	246	5.0e-51	194	COG1414	DNA-binding transcriptional regulator, IclR family	246
650824462	270	30.27	12	267	3	253	3.0e-50	192	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
650824465	455	49.61	5	382	22	398	1.0e-118	420	COG0513	Superfamily II DNA and RNA helicase	513
650824466	114	25.74	9	108	4	104	9.0e-08	49	COG4392	Branched-chain amino acid transport protein	107
650824467	248	34.36	14	238	7	226	2.0e-26	112	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
650824468	306	39.93	7	296	1	284	2.0e-68	252	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
650824469	70	42.55	17	63	18	62	3.0e-07	46.9	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
650824470	140	20.34	7	120	14	129	4.0e-04	37.2	COG4319	Ketosteroid isomerase homolog	137
650824471	363	37.53	2	360	12	338	2.0e-77	282	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
650824472	461	35.06	1	461	36	481	3.0e-74	272	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
650824473	287	22.31	7	251	10	253	1.0e-14	73.8	COG3336	Cytochrome c oxidase assembly factor CtaG	299
650824476	384	33.92	4	379	1	383	1.0e-44	174	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
650824477	353	45.4	1	324	2	322	8.0e-94	337	COG0042	tRNA-dihydrouridine synthase	323
650824479	530	61.02	3	530	2	515	0.0e+00	736	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
650824480	182	59.06	4	152	1	149	5.0e-50	190	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
650824481	192	46.5	1	188	1	200	2.0e-54	205	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
650824482	322	45	1	316	2	321	4.0e-96	344	COG1171	Threonine dehydratase	347
650824483	339	69.57	6	327	9	330	0.0e+00	531	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
650824484	605	48.6	1	604	1	585	0.0e+00	682	COG0514	Superfamily II DNA helicase RecQ	590
650824486	595	36.92	29	434	22	430	2.0e-65	244	COG0038	H+/Cl- antiporter ClcA	443
650824487	233	47.37	7	233	2	227	1.0e-59	223	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650824488	444	24.92	144	444	23	332	3.0e-31	129	COG0642	Signal transduction histidine kinase	336
650824489	349	28.78	19	337	6	336	5.0e-34	138	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
650824490	427	31.29	3	419	21	442	2.0e-59	223	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
650824491	588	31.82	49	563	7	472	2.0e-91	330	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
650824492	267	35.29	15	267	2	219	3.0e-42	165	COG0850	Septum formation inhibitor MinC	219
650824493	271	66.42	1	271	1	270	4.0e-118	417	COG2894	Septum formation inhibitor-activating ATPase MinD	272
650824494	86	54.65	1	86	1	86	3.0e-23	99	COG0851	Septum formation topological specificity factor MinE	88
650824496	180	22.77	4	161	1	202	1.0e-09	56	COG1335	Nicotinamidase-related amidase	205
650824497	557	47.9	3	540	1	530	0.0e+00	567	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
650824499	314	19.53	7	303	4	291	2.0e-19	89.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
650824501	1911	42.24	1	989	2	932	0.0e+00	1080	COG0178	Excinuclease UvrABC ATPase subunit	935
650824503	223	23.45	8	206	30	252	5.0e-22	97.8	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
650824504	110	57.8	3	110	1	109	4.0e-24	102	COG1742	Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily	109
650824506	293	37.46	1	290	1	259	1.0e-65	243	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
650824507	216	44.63	37	208	7	182	6.0e-46	177	COG3703	Cation transport regulator ChaC	190
650824508	218	58.49	10	218	4	214	3.0e-77	281	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
650824509	174	36.88	8	162	4	159	2.0e-26	112	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
650824510	374	34.13	4	370	3	375	3.0e-76	279	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
650824511	282	52.3	1	282	5	287	5.0e-112	397	COG0788	Formyltetrahydrofolate hydrolase	287
650824512	572	45.42	31	571	8	538	0.0e+00	544	COG0405	Gamma-glutamyltranspeptidase	539
650824513	294	28.77	1	287	3	291	5.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
650824514	589	35.93	38	573	4	537	0.0e+00	506	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
650824515	397	37.4	15	397	1	393	4.0e-81	295	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650824516	139	35.2	9	132	34	154	9.0e-22	95.9	COG2030	Acyl dehydratase	159
650824517	267	24.45	32	267	19	282	2.0e-17	83.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650824518	346	40.89	1	224	5	211	2.0e-51	196	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
650824519	393	51.34	15	386	3	367	2.0e-117	415	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
650824520	174	60.26	11	166	2	155	9.0e-52	196	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
650824521	293	33.68	10	291	1	245	7.0e-63	234	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
650824522	354	48.48	1	329	1	286	6.0e-100	357	COG0191	Fructose/tagatose bisphosphate aldolase	286
650824523	201	45.76	2	177	11	169	2.0e-44	171	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
650824524	397	52.22	1	395	1	394	0.0e+00	464	COG0126	3-phosphoglycerate kinase	395
650824525	337	59.76	2	337	1	333	6.0e-125	440	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
650824526	671	58.81	1	671	9	662	0.0e+00	977	COG0021	Transketolase	663
650824527	247	37.4	4	245	1	245	2.0e-57	215	COG1385	16S rRNA U1498 N3-methylase RsmE	246
650824528	155	25.3	36	118	1	80	6.0e-06	43.7	COG2732	Barstar, RNAse (barnase) inhibitor	91
650824529	400	24.49	10	346	12	289	1.0e-19	90.9	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
650824530	764	53.79	1	432	13	432	0.0e+00	544	COG0281	Malic enzyme	432
650824532	385	40.77	6	384	1	389	2.0e-100	359	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
650824534	514	53.7	1	514	1	475	0.0e+00	624	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
650824536	139	25.21	2	120	13	129	1.0e-08	52.2	COG5393	Uncharacterized membrane protein YqjE	131
650824537	105	39.22	4	105	3	104	2.0e-18	84.2	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
650824539	212	56.94	1	208	2	210	2.0e-73	268	COG0035	Uracil phosphoribosyltransferase	210
650824540	486	27.78	24	486	6	466	5.0e-65	242	COG2027	D-alanyl-D-alanine carboxypeptidase	470
650824542	346	54.81	5	340	1	342	5.0e-127	447	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
650824543	380	60.65	8	378	1	365	0.0e+00	541	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
650824544	114	40.59	14	114	1	97	7.0e-21	92.6	COG1862	Preprotein translocase subunit YajC	97
650824545	624	51.38	110	615	17	506	0.0e+00	474	COG0342	Preprotein translocase subunit SecD	506
650824546	311	44.77	1	305	1	304	3.0e-81	295	COG0341	Preprotein translocase subunit SecF	305
650824548	113	28.7	1	111	20	130	1.0e-04	38.8	COG2010	Cytochrome c, mono- and diheme variants	150
650824549	407	23.49	9	286	4	252	3.0e-31	129	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
650824550	497	49.44	47	487	1	436	0.0e+00	544	COG0621	tRNA A37 methylthiotransferase MiaB	437
650824551	337	50.91	8	331	12	330	4.0e-102	364	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
650824552	164	47.29	34	159	22	150	8.0e-32	129	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
650824554	267	43.82	3	267	28	293	2.0e-76	279	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
650824555	542	36.1	2	539	9	514	2.0e-90	326	COG0815	Apolipoprotein N-acyltransferase	518
650824556	272	37.37	4	190	5	188	1.0e-31	130	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
650824560	236	23.53	16	233	4	204	4.0e-15	75	COG0778	Nitroreductase	207
650824562	715	22.7	6	715	4	768	2.0e-51	197	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
650824564	760	54.48	1	432	13	432	0.0e+00	553	COG0281	Malic enzyme	432
650824565	327	22.88	17	321	1	297	9.0e-19	87.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
650824566	347	60.26	22	326	14	318	5.0e-117	414	COG0502	Biotin synthase or related enzyme	335
650824567	483	26.59	36	371	43	380	1.0e-08	54.8	COG2814	Predicted arabinose efflux permease, MFS family	394
650824568	168	48.81	1	167	1	165	8.0e-60	222	COG0678	Peroxiredoxin	165
650824570	165	57.42	9	163	2	155	7.0e-55	206	COG0315	Molybdenum cofactor biosynthesis enzyme	157
650824571	83	27.59	5	83	1	84	1.0e-08	51.5	COG1977	Molybdopterin converting factor, small subunit	84
650824572	156	43.45	1	145	5	146	5.0e-39	153	COG0314	Molybdopterin synthase catalytic subunit	149
650824573	172	41.46	8	169	3	165	8.0e-45	173	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
650824574	401	41.15	1	399	6	404	4.0e-106	378	COG0303	Molybdopterin biosynthesis enzyme	404
650824575	209	38.65	2	205	1	190	2.0e-35	142	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
650824576	360	45.97	26	360	4	322	2.0e-100	359	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
650824577	368	32.84	154	351	24	219	1.0e-34	140	COG1910	Periplasmic molybdate-binding protein/domain	223
650824578	168	34.64	11	163	3	155	3.0e-36	144	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
650824579	523	52.64	96	510	1	416	0.0e+00	556	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
650824580	981	44.87	19	943	2	959	0.0e+00	1172	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
650824581	286	44.12	7	278	2	262	5.0e-71	261	COG1526	Formate dehydrogenase assembly factor FdhD	266
650824585	159	38.67	6	153	4	151	5.0e-19	87.3	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
650824586	113	40	4	108	2	105	1.0e-23	101	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
650824587	201	42.77	26	190	4	168	4.0e-44	171	COG1247	L-amino acid N-acyltransferase YncA	169
650824588	134	29.63	9	114	16	123	4.0e-16	76.9	COG2346	Truncated hemoglobin YjbI	133
650824589	399	30.23	20	399	12	393	1.0e-46	181	COG3213	Uncharacterized protein involved in response to NO	396
650824590	151	44.27	1	130	1	131	5.0e-30	123	COG1959	DNA-binding transcriptional regulator, IscR family	150
650824591	146	30.84	27	133	1	104	3.0e-05	41.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
650824592	399	41.36	1	321	3	318	9.0e-81	294	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
650824593	542	41.42	8	541	2	538	0.0e+00	551	COG0405	Gamma-glutamyltranspeptidase	539
650824594	292	28.38	3	292	2	293	5.0e-29	121	COG0583	DNA-binding transcriptional regulator, LysR family	297
650824595	427	20.4	39	410	54	429	2.0e-08	54	COG2271	Sugar phosphate permease	448
650824596	132	38.18	20	129	8	116	2.0e-19	88	COG3671	Uncharacterized membrane protein	125
650824597	363	59.68	1	363	1	372	0.0e+00	491	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
650824599	198	50	4	193	1	187	1.0e-63	235	COG0193	Peptidyl-tRNA hydrolase	190
650824600	207	45.16	1	93	2	93	2.0e-24	105	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
650824601	290	59.31	1	288	26	313	4.0e-111	394	COG0462	Phosphoribosylpyrophosphate synthetase	314
650824603	307	45.74	1	276	1	271	2.0e-74	272	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
650824604	194	24.87	15	192	12	201	2.0e-15	75.8	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
650824605	258	46.15	1	257	18	273	3.0e-76	278	COG0266	Formamidopyrimidine-DNA glycosylase	273
650824606	317	21	38	246	30	236	2.0e-12	66.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650824607	556	24.93	21	397	1	377	1.0e-53	204	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
650824609	433	64.04	2	432	1	426	0.0e+00	556	COG3508	Homogentisate 1,2-dioxygenase	427
650824610	439	23.05	110	402	37	266	8.0e-25	108	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
650824611	480	38.38	16	479	1	456	1.0e-94	340	COG0277	FAD/FMN-containing dehydrogenase	459
650824612	463	36.28	12	452	10	457	3.0e-100	358	COG1109	Phosphomannomutase	464
650824613	764	25.2	407	764	22	380	3.0e-32	134	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650824614	378	26.87	1	371	3	380	4.0e-33	135	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650824615	638	29.84	1	615	1	524	6.0e-89	322	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
650824616	374	27.44	9	372	4	375	9.0e-33	134	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650824617	450	25	22	425	13	421	5.0e-31	129	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
650824618	341	35.87	20	341	4	313	6.0e-49	188	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650824619	424	41.77	5	415	9	423	5.0e-126	444	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
650824620	379	25.37	10	340	7	319	4.0e-31	129	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
650824621	229	42.18	20	229	1	204	1.0e-50	193	COG2941	Demethoxyubiquinone hydroxylase, CLK1/Coq7/Cat5 family	204
650824623	203	23.08	4	203	5	205	7.0e-17	80.8	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
650824624	198	28.21	67	183	44	149	2.0e-09	55.7	COG2010	Cytochrome c, mono- and diheme variants	150
650824625	197	35.84	7	177	13	181	5.0e-41	160	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
650824626	556	32.81	99	527	15	462	1.0e-117	416	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
650824628	140	39.86	1	138	2	136	1.0e-29	122	COG1765	Uncharacterized OsmC-related protein	137
650824629	264	65.41	1	264	3	268	7.0e-118	416	COG0207	Thymidylate synthase	268
650824630	166	44.58	5	163	1	166	6.0e-38	150	COG0262	Dihydrofolate reductase	167
650824631	477	30.57	13	475	1	452	3.0e-89	322	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
650824632	441	40.72	1	440	1	444	0.0e+00	483	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
650824633	968	61.8	461	927	24	496	0.0e+00	699	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
650824634	126	55.47	1	125	3	130	1.0e-34	138	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
650824635	364	47.49	1	361	1	374	1.0e-99	356	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
650824636	422	45.65	9	421	4	405	1.0e-122	433	COG2081	Predicted flavoprotein YhiN	408
650824637	753	41.21	142	752	1	557	0.0e+00	582	COG1982	Arginine/lysine/ornithine decarboxylase	557
650824638	187	40.31	3	187	2	181	2.0e-56	212	COG0717	Deoxycytidine triphosphate deaminase	183
650824639	1205	20.51	60	1200	145	1275	5.0e-49	190	COG2911	Autotransporter translocation and assembly factor TamB	1278
650824640	590	22.36	33	590	39	594	1.0e-56	214	COG0729	Outer membrane translocation and assembly module TamA	594
650824641	361	40.59	44	309	5	262	2.0e-54	206	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
650824643	690	36.47	1	562	3	554	0.0e+00	558	COG0143	Methionyl-tRNA synthetase	558
650824644	305	41.81	3	300	1	298	4.0e-68	251	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
650824645	512	22.28	9	362	1	385	2.0e-18	87.6	COG2814	Predicted arabinose efflux permease, MFS family	394
650824646	253	36.18	9	251	1	246	2.0e-39	156	COG1414	DNA-binding transcriptional regulator, IclR family	246
650824647	594	42.76	5	576	7	572	0.0e+00	591	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
650824648	344	40.06	7	342	2	332	9.0e-85	307	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650824649	426	51.19	47	425	1	378	3.0e-91	328	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650824650	166	31.93	1	166	12	177	1.0e-18	86.1	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
650824651	390	57.22	1	388	1	379	0.0e+00	466	COG3970	Fumarylacetoacetate (FAA) hydrolase family protein	379
650824656	273	47.3	57	273	4	225	7.0e-67	247	COG0220	tRNA G46 methylase TrmB	227
650824657	310	24.92	11	305	2	277	2.0e-13	70.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650824658	68	42.65	1	68	1	68	8.0e-14	68.7	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
650824659	471	54.39	1	466	1	451	0.0e+00	584	COG0541	Signal recognition particle GTPase	451
650824660	281	35.51	6	281	4	264	2.0e-36	146	COG4137	ABC-type uncharacterized transport system, permease component	265
650824663	637	59.71	7	632	1	618	0.0e+00	822	COG0326	Molecular chaperone, HSP90 family	623
650824664	759	48.52	4	746	2	714	0.0e+00	715	COG3256	Nitric oxide reductase large subunit	717
650824665	48	37.5	1	40	2	41	2.0e-03	34.2	COG5510	Predicted small secreted protein	44
650824666	428	39.47	46	425	1	378	9.0e-78	284	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650824667	186	34.94	16	181	2	164	5.0e-15	74.2	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
650824668	330	30.06	6	330	8	329	2.0e-51	196	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650824670	419	35.71	27	413	1	391	6.0e-85	308	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650824671	316	27.91	1	299	1	297	1.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
650824673	362	24.22	86	359	35	298	2.0e-12	66.8	COG4974	Site-specific recombinase XerD	300
650824686	360	17	6	297	45	338	5.0e-14	72.3	COG3704	Type IV secretory pathway, VirB6 components	406
650824689	375	29.01	5	366	2	346	4.0e-61	228	COG3177	Fic family protein	348
650824691	425	30.94	54	405	59	419	1.0e-64	241	COG4268	5-methylcytosine-specific restriction endonuclease McrBC, regulatory subunit McrC	439
650824692	520	33.9	1	517	3	489	5.0e-106	378	COG0286	Type I restriction-modification system, DNA methylase subunit	489
650824693	439	20.33	5	427	1	391	4.0e-22	99.7	COG0732	Restriction endonuclease S subunit	391
650824695	1074	33.4	1	1045	6	962	0.0e+00	639	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
650824697	639	29.08	13	638	1	642	3.0e-82	300	COG0210	Superfamily I DNA or RNA helicase	655
650824700	532	40	116	274	2	157	1.0e-24	108	COG3436	Transposase	157
650824702	466	37.11	51	208	3	157	7.0e-25	109	COG3436	Transposase	157
650824706	519	29.02	1	453	1	472	2.0e-59	223	COG3119	Arylsulfatase A or related enzyme	475
650824707	338	39.16	26	334	10	316	1.0e-61	230	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650824708	490	45.32	18	485	2	465	3.0e-129	455	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650824709	224	29.3	1	212	5	201	9.0e-17	80.4	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
650824710	319	30.23	15	314	1	295	2.0e-28	119	COG0583	DNA-binding transcriptional regulator, LysR family	297
650824718	792	66.12	16	384	13	361	5.0e-129	455	COG4951	Uncharacterized protein	361
650824719	149	38.52	24	144	5	120	8.0e-18	83.1	COG5499	Antitoxin component HigA of the HigAB toxin-antitoxin module, contains an N-terminal HTH domain	120
650824720	183	34.74	91	183	1	95	4.0e-19	87.7	COG4680	mRNA-degrading endonuclease (mRNA interferase) HigB, toxic component of the HigAB toxin-antitoxin module	98
650824723	212	52.17	1	207	1	204	3.0e-74	271	COG2808	Predicted FMN-binding regulatory protein PaiB	209
650824724	387	33.33	22	387	12	367	5.0e-55	208	COG0387	Ca2+/H+ antiporter	368
650824728	311	29.14	12	288	8	277	5.0e-47	181	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
650824730	390	42.26	7	383	2	380	6.0e-94	338	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650824732	332	32.2	1	322	24	377	2.0e-64	239	COG1454	Alcohol dehydrogenase, class IV	377
650824733	334	36.48	14	330	1	316	1.0e-64	240	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650824734	303	34.24	1	290	1	290	2.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
650824736	145	61.81	1	144	1	144	9.0e-55	205	COG1490	D-Tyr-tRNAtyr deacylase	145
650824737	162	26.03	1	146	2	133	6.0e-17	80.5	COG3791	Uncharacterized conserved protein	133
650824738	289	31.12	8	273	21	306	4.0e-34	138	COG2367	Beta-lactamase class A	329
650824742	165	31.55	1	165	6	166	8.0e-10	56.6	COG3652	Predicted outer membrane protein	170
650824744	226	34.98	1	226	1	242	9.0e-33	133	COG3279	DNA-binding response regulator, LytR/AlgR family	244
650824749	209	34	4	202	24	222	1.0e-25	110	COG1802	DNA-binding transcriptional regulator, GntR family	230
650824750	206	41.05	3	191	9	197	1.0e-37	150	COG0684	Regulator of RNase E activity RraA	210
650824751	329	38.92	12	325	5	316	5.0e-65	241	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650824752	588	20.93	92	588	34	458	8.0e-33	135	COG0471	Di- and tricarboxylate transporter	461
650824753	330	37.85	13	326	1	316	1.0e-75	277	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650824754	345	39.77	2	345	43	369	1.0e-70	260	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
650824756	232	32.6	7	231	12	236	8.0e-39	154	COG2186	DNA-binding transcriptional regulator, FadR family	241
650824758	252	28.22	10	247	1	239	7.0e-30	124	COG1414	DNA-binding transcriptional regulator, IclR family	246
650824759	267	32.7	1	259	2	256	2.0e-40	159	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650824760	694	33.87	5	620	4	596	3.0e-91	329	COG1042	Acyl-CoA synthetase (NDP forming)	598
650824761	321	38.56	3	319	2	318	2.0e-68	253	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650824762	373	34.78	16	372	33	392	3.0e-55	209	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650824764	238	32.46	11	234	8	233	2.0e-31	129	COG2186	DNA-binding transcriptional regulator, FadR family	241
650824766	290	44.85	20	288	9	261	6.0e-72	264	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
650824767	321	45.34	1	321	1	319	4.0e-71	261	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650824768	202	24.46	1	182	3	186	5.0e-08	51.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650824769	380	22.86	1	378	8	387	9.0e-11	61.8	COG2814	Predicted arabinose efflux permease, MFS family	394
650824771	302	34.26	195	302	18	125	2.0e-20	93.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650824772	416	40.1	14	395	7	390	1.0e-61	230	COG2814	Predicted arabinose efflux permease, MFS family	394
650824773	255	36.11	7	252	6	249	2.0e-41	162	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650824774	330	33.02	11	327	4	317	2.0e-56	213	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650824775	450	24.74	37	411	2	375	2.0e-41	164	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
650824776	673	35.63	3	575	2	562	0.0e+00	462	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
650824777	676	37.04	2	673	8	674	0.0e+00	528	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
650824778	158	21.81	2	153	58	244	5.0e-08	50.6	COG1414	DNA-binding transcriptional regulator, IclR family	246
650824779	322	38.73	7	321	8	319	7.0e-61	227	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650824780	325	28.81	13	303	4	295	4.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
650824781	413	39.57	28	399	3	348	1.0e-91	330	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
650824782	144	26.24	11	140	1	134	6.0e-23	99	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
650824785	148	30.87	3	144	7	149	2.0e-16	78.2	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
650824786	111	67.8	1	59	1	59	3.0e-17	80.3	COG3422	Uncharacterized conserved protein YegP, UPF0339 family	59
650824787	324	35.74	6	323	4	319	7.0e-61	227	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650824788	214	36.97	1	206	20	230	2.0e-29	122	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
650824789	109	33.65	4	107	2	105	5.0e-10	56.4	COG1687	Branched-chain amino acid transport protein AzlD	106
650824790	222	24.41	9	220	16	227	3.0e-22	99	COG1802	DNA-binding transcriptional regulator, GntR family	230
650824791	283	37.08	4	266	12	264	5.0e-60	224	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
650824793	451	34.27	28	439	43	468	5.0e-76	278	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
650824794	507	50	262	506	1	240	2.0e-91	329	COG1126	ABC-type polar amino acid transport system, ATPase component	240
650824795	293	25.55	20	284	5	271	5.0e-25	108	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650824796	483	31.45	14	481	4	460	8.0e-47	181	COG0471	Di- and tricarboxylate transporter	461
650824797	294	25.61	9	293	3	280	5.0e-21	95.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650824798	215	41.09	1	201	1	190	3.0e-49	188	COG0066	3-isopropylmalate dehydratase small subunit	191
650824799	473	48.3	7	472	2	423	0.0e+00	538	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
650824800	296	33.45	5	291	4	290	7.0e-33	134	COG0583	DNA-binding transcriptional regulator, LysR family	297
650824801	413	22.77	30	408	18	392	6.0e-11	62.1	COG2814	Predicted arabinose efflux permease, MFS family	394
650824802	322	33.97	3	317	1	314	8.0e-65	240	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650824804	472	21.66	1	466	6	419	2.0e-26	113	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
650824805	307	31.01	1	283	1	282	7.0e-26	111	COG0583	DNA-binding transcriptional regulator, LysR family	297
650824807	321	38.77	3	321	1	322	9.0e-79	287	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
650824809	223	25.49	23	221	62	257	6.0e-17	81.1	COG3455	Type VI protein secretion system component VasF	262
650824810	465	29.07	8	465	6	446	8.0e-47	181	COG3522	Predicted component of the type VI protein secretion system	446
650824811	235	21.01	9	143	2	126	3.0e-06	45.7	COG3521	Predicted component of the type VI protein secretion system	159
650824814	315	27.34	39	293	3	238	1.0e-15	77.6	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
650824815	880	25	585	844	7	236	9.0e-24	106	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
650824816	831	23.99	22	574	23	546	2.0e-65	244	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
650824817	890	42.86	12	848	1	766	0.0e+00	759	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
650824818	346	28.32	1	328	1	335	2.0e-35	143	COG3520	Predicted component of the type VI protein secretion system	335
650824819	574	33.81	4	574	7	621	5.0e-99	355	COG3519	Type VI protein secretion system component VasA	621
650824820	121	27.48	1	120	26	155	4.0e-10	56.9	COG3518	Predicted component of the type VI protein secretion system	157
650824822	495	53.02	1	494	1	492	0.0e+00	679	COG3517	Predicted component of the type VI protein secretion system	495
650824823	172	41.32	3	167	6	169	5.0e-40	157	COG3516	Predicted component of the type VI protein secretion system	169
650824828	125	47.97	7	125	18	138	1.0e-32	131	COG4315	Predicted lipoprotein with conserved Yx(FWY)xxD motif (function unknown)	138
650824829	949	28.47	39	582	133	635	3.0e-96	347	COG0209	Ribonucleotide reductase alpha subunit	696
650824830	171	49.13	1	170	9	179	4.0e-42	164	COG2032	Cu/Zn superoxide dismutase	179
650824833	299	41.43	30	239	11	202	2.0e-55	209	COG0437	Fe-S-cluster-containing dehydrogenase component	203
650824834	215	48.31	4	208	1	206	2.0e-51	195	COG2864	Cytochrome b subunit of formate dehydrogenase	218
650824835	312	40.65	3	309	4	308	3.0e-66	245	COG3058	Formate dehydrogenase maturation protein FdhE	308
650824836	482	55.19	85	479	12	394	5.0e-107	381	COG1921	Seryl-tRNA(Sec) selenium transferase	395
650824837	641	38.78	1	474	1	446	9.0e-98	351	COG3276	Selenocysteine-specific translation elongation factor	447
650824838	353	49.28	8	353	3	346	1.0e-100	360	COG0709	Selenophosphate synthase	346
650824839	308	55.37	1	304	1	302	1.0e-83	303	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
650824841	255	34.82	9	255	1	246	8.0e-45	173	COG1414	DNA-binding transcriptional regulator, IclR family	246
650824842	468	22.32	1	465	2	442	2.0e-47	183	COG2610	H+/gluconate symporter or related permease	442
650824843	358	48.42	7	196	1	187	1.0e-54	207	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
650824844	418	26.42	9	418	6	381	1.0e-42	167	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
650824847	375	25.28	25	371	29	361	3.0e-57	216	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
650824848	259	44.93	29	253	1	220	2.0e-68	252	COG0692	Uracil DNA glycosylase	223
650824851	260	28.5	27	231	4	209	1.0e-36	146	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
650824852	204	28.92	1	197	1	201	2.0e-23	102	COG0625	Glutathione S-transferase	211
650824853	322	37.19	1	319	1	317	3.0e-61	229	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650824854	298	24.75	3	297	1	297	3.0e-18	86.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
650824855	210	39.6	10	209	1	202	5.0e-31	127	COG1279	Arginine exporter protein ArgO	202
650824857	291	42.31	38	290	4	256	6.0e-65	240	COG0171	NH3-dependent NAD+ synthetase	268
650824858	402	18.88	30	395	50	438	7.0e-15	75.2	COG2271	Sugar phosphate permease	448
650824859	561	51.78	6	559	10	571	0.0e+00	715	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
650824860	156	40.28	13	156	5	148	8.0e-21	93.1	COG3399	Uncharacterized protein	148
650824861	249	38.04	1	249	1	250	2.0e-38	153	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650824864	334	37.42	14	330	5	316	4.0e-62	232	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650824865	246	65.29	4	245	1	240	4.0e-116	410	COG1126	ABC-type polar amino acid transport system, ATPase component	240
650824866	365	41.59	138	363	2	222	5.0e-51	195	COG0765	ABC-type amino acid transport system, permease component	222
650824867	394	49.37	1	394	3	397	6.0e-122	431	COG4597	ABC-type amino acid transport system, permease component	397
650824868	338	29.81	1	259	2	261	4.0e-28	118	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650824869	223	48.85	1	217	1	217	8.0e-69	253	COG2884	ABC-type ATPase involved in cell division	223
650824870	302	32.21	4	301	2	292	7.0e-41	161	COG2177	Cell division protein FtsX	297
650824871	359	41.36	1	353	1	340	4.0e-95	341	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
650824872	378	41.73	6	375	5	373	1.0e-75	277	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
650824873	638	35.45	12	622	10	599	6.0e-127	448	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
650824874	191	28.48	29	183	3	160	8.0e-12	63.7	COG2891	Cell shape-determining protein MreD	167
650824875	294	30.82	8	285	1	279	1.0e-45	176	COG1792	Cell shape-determining protein MreC	284
650824876	335	65.27	1	332	9	339	6.0e-126	443	COG1077	Actin-like ATPase involved in cell morphogenesis	342
650824877	102	38.24	1	102	1	95	2.0e-19	87.6	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
650824878	510	49.5	13	508	9	475	2.0e-128	453	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
650824879	484	55.03	1	484	4	481	0.0e+00	679	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
650824880	223	38.53	7	221	3	201	2.0e-45	175	COG0461	Orotate phosphoribosyltransferase	201
650824881	122	30.16	2	121	16	139	6.0e-07	46.5	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
650824882	260	40.6	2	258	1	261	2.0e-79	289	COG0708	Exonuclease III	261
650824883	204	50.25	1	202	5	207	3.0e-54	204	COG2860	Uncharacterized membrane protein YeiH	209
650824884	410	23.33	72	398	70	384	2.0e-04	41	COG2814	Predicted arabinose efflux permease, MFS family	394
650824886	417	50.27	29	400	10	368	1.0e-127	449	COG2021	Homoserine acetyltransferase	368
650824889	522	46.59	7	513	8	515	0.0e+00	520	COG2918	Gamma-glutamylcysteine synthetase	518
650824890	189	49.74	1	186	1	189	6.0e-40	157	COG1971	Putative Mn2+ efflux pump MntP	190
650824891	194	28.27	1	190	5	189	7.0e-35	140	COG5553	Predicted metal-dependent enzyme of the double-stranded beta helix superfamily	191
650824892	239	31.22	1	226	3	237	2.0e-28	119	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650824893	387	49.6	7	380	8	380	2.0e-110	392	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650824894	255	41.3	3	247	1	246	5.0e-53	201	COG1414	DNA-binding transcriptional regulator, IclR family	246
650824895	412	29.32	15	390	28	371	1.0e-51	197	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
650824896	115	33.64	7	115	15	124	9.0e-14	68.9	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
650824897	328	37.42	16	327	8	319	7.0e-63	234	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650824898	499	33.91	1	495	10	525	8.0e-98	351	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650824899	248	38.37	1	245	3	257	1.0e-41	162	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650824900	327	29.39	2	323	1	324	2.0e-50	192	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
650824902	251	49.8	1	243	3	244	1.0e-71	262	COG3967	Short-chain dehydrogenase involved in D-alanine esterification of teichoic acids	245
650824903	140	41.67	30	137	13	119	1.0e-23	102	COG1733	DNA-binding transcriptional regulator, HxlR family	120
650824904	113	65.18	2	113	1	112	3.0e-45	173	COG2824	Uncharacterized Zn-ribbon-containing protein	112
650824906	309	49.21	185	309	3	126	4.0e-18	85.5	COG3245	Cytochrome c5	126
650824907	511	46.48	3	286	2	285	2.0e-90	326	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
650824908	406	50.12	1	406	1	392	1.0e-126	447	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650824909	327	31.23	13	313	13	328	5.0e-61	228	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
650824911	717	39.31	11	695	1	649	0.0e+00	530	COG0210	Superfamily I DNA or RNA helicase	655
650824912	703	40.24	24	703	3	730	0.0e+00	647	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
650824913	358	49.43	8	357	5	352	1.0e-115	410	COG0407	Uroporphyrinogen-III decarboxylase	352
650824915	141	48.89	1	134	1	135	2.0e-28	118	COG0355	FoF1-type ATP synthase, epsilon subunit	135
650824916	473	72.9	1	472	1	465	0.0e+00	806	COG0055	FoF1-type ATP synthase, beta subunit	468
650824917	303	44.82	5	303	1	286	3.0e-89	321	COG0224	FoF1-type ATP synthase, gamma subunit	287
650824918	513	67.65	1	510	1	499	0.0e+00	808	COG0056	FoF1-type ATP synthase, alpha subunit	504
650824919	180	37.99	1	178	1	177	4.0e-34	137	COG0712	FoF1-type ATP synthase, delta subunit	178
650824920	124	33.06	1	124	35	158	3.0e-04	37.5	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
650824922	80	41.33	3	77	5	79	4.0e-05	39.8	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
650824923	293	32.88	2	293	1	246	8.0e-40	157	COG0356	FoF1-type ATP synthase, membrane subunit a	246
650824925	258	41.86	1	255	2	257	1.0e-58	219	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650824926	597	40.48	8	585	3	532	0.0e+00	464	COG3975	Predicted metalloprotease, contains C-terminal PDZ domain	558
650824927	300	26.98	8	300	4	304	8.0e-27	114	COG0492	Thioredoxin reductase	305
650824928	119	26.96	5	119	4	118	2.0e-16	77.9	COG1539	Dihydroneopterin aldolase	121
650824929	323	33.2	31	277	1	243	3.0e-48	185	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
650824930	799	30	462	775	1	315	2.0e-31	131	COG0668	Small-conductance mechanosensitive channel	316
650824931	190	54.45	3	190	1	190	7.0e-73	266	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
650824932	108	62.86	1	105	1	105	3.0e-42	163	COG0278	Glutaredoxin-related protein	105
650824933	285	46.86	10	278	5	272	7.0e-67	247	COG2890	Methylase of polypeptide chain release factors	280
650824934	355	63.87	1	353	5	361	0.0e+00	528	COG0216	Protein chain release factor A	363
650824935	406	45.86	1	399	17	409	1.0e-115	410	COG0373	Glutamyl-tRNA reductase	414
650824937	435	21.3	87	408	3	308	6.0e-06	45.7	COG0582	Integrase	309
650824939	520	37.89	105	263	1	157	2.0e-25	110	COG3436	Transposase	157
650824940	508	44.06	21	503	1	472	0.0e+00	491	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650824941	419	21.61	25	405	8	383	1.0e-10	61.4	COG2807	Cyanate permease	395
650824943	346	25	130	329	34	211	2.0e-15	76.6	COG0543	NAD(P)H-flavin reductase	252
650824944	337	25.51	3	285	2	294	6.0e-41	161	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
650824945	299	51.97	5	291	2	304	2.0e-86	312	COG4569	Acetaldehyde dehydrogenase (acetylating)	310
650824946	426	37.73	48	426	2	376	2.0e-59	223	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650824947	157	23.19	4	141	22	157	3.0e-07	48	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
650824948	397	22.66	48	302	22	267	4.0e-29	122	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650824950	410	21.35	20	368	5	346	3.0e-31	129	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
650824951	303	27.39	49	289	1	240	3.0e-36	145	COG1414	DNA-binding transcriptional regulator, IclR family	246
650824966	137	38.79	14	129	1	116	4.0e-18	84.1	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
650824967	598	54.06	9	580	3	560	0.0e+00	612	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
650824968	259	55.02	29	257	4	230	1.0e-84	306	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
650824973	90	35.71	1	84	3	82	1.0e-13	68.4	COG3905	Predicted transcriptional regulator	83
650824974	97	30.85	1	93	1	89	1.0e-05	41.2	COG3668	Plasmid stabilization system protein ParE	98
650824977	153	25.66	2	153	32	182	1.0e-16	79.3	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
650824978	236	33.18	24	229	4	214	9.0e-38	150	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
650824979	634	41.47	9	614	93	713	0.0e+00	576	COG2217	Cation transport ATPase	713
650824980	73	33.8	1	71	1	71	4.0e-09	53.1	COG2608	Copper chaperone CopZ	71
650824987	75	27.85	1	71	5	83	2.0e-05	40.5	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
650824988	111	26.26	5	103	3	96	1.0e-07	48.1	COG3668	Plasmid stabilization system protein ParE	98
650824991	137	37.98	5	132	11	135	2.0e-12	65	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
650824992	264	36	24	262	1	243	4.0e-41	161	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
650824993	321	27.33	3	297	2	292	3.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
650824994	494	33.15	1	488	6	534	4.0e-101	362	COG0659	Sulfate permease or related transporter, MFS superfamily	554
650824995	400	45.25	1	396	2	390	3.0e-117	415	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
650824996	281	38.35	11	272	5	260	5.0e-51	194	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
650824999	673	20.22	17	673	54	768	5.0e-29	123	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
650825001	773	28.66	346	679	2	330	5.0e-38	153	COG0642	Signal transduction histidine kinase	336
650825004	266	30.77	120	262	52	187	8.0e-25	107	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
650825005	2139	22.18	1555	2139	135	715	1.0e-05	47.5	COG5295	Autotransporter adhesin	715
650825008	413	37.1	13	410	6	408	2.0e-102	366	COG2081	Predicted flavoprotein YhiN	408
650825010	384	50	5	384	6	392	3.0e-97	348	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650825011	239	22.67	1	239	1	244	3.0e-19	89.1	COG1651	Protein-disulfide isomerase	244
650825012	389	33.67	5	387	4	382	6.0e-53	201	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
650825013	429	32.81	54	426	1	371	1.0e-73	270	COG2821	Membrane-bound lytic murein transglycosylase	373
650825014	124	57.85	4	124	6	126	5.0e-46	176	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
650825015	233	56.05	6	228	3	220	5.0e-86	310	COG0036	Pentose-5-phosphate-3-epimerase	220
650825016	241	38.57	12	234	2	220	9.0e-42	163	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
650825017	506	46.3	18	499	1	458	0.0e+00	473	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
650825018	187	62.23	1	187	3	190	2.0e-82	298	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
650825019	343	49.4	7	340	6	338	3.0e-108	385	COG0547	Anthranilate phosphoribosyltransferase	338
650825020	264	54.65	5	262	1	254	1.0e-85	309	COG0134	Indole-3-glycerol phosphate synthase	254
650825021	492	44.78	257	486	36	265	7.0e-75	275	COG2326	Polyphosphate kinase 2, PPK2 family	270
650825022	164	22.22	11	136	1	135	2.0e-19	88.9	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
650825023	550	41.19	1	485	29	511	1.0e-120	427	COG0513	Superfamily II DNA and RNA helicase	513
650825024	555	35.87	16	548	3	531	2.0e-120	426	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
650825025	313	29.04	1	302	1	296	7.0e-27	114	COG0583	DNA-binding transcriptional regulator, LysR family	297
650825026	325	38.85	9	322	6	317	1.0e-69	256	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650825027	324	31.15	3	321	1	310	2.0e-54	205	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
650825029	392	36.74	39	380	16	364	2.0e-70	260	COG1565	SAM-dependent methyltransferase, MidA family	370
650825031	721	30.46	414	705	3	296	1.0e-30	128	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
650825032	212	31	12	204	8	187	2.0e-25	109	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
650825033	281	40.88	8	277	17	287	7.0e-68	250	COG0685	5,10-methylenetetrahydrofolate reductase	291
650825034	112	50.45	1	110	2	112	3.0e-12	64	COG1950	Uncharacterized membrane protein YvlD, DUF360 family	120
650825035	475	56.67	14	467	4	420	0.0e+00	636	COG0499	S-adenosylhomocysteine hydrolase	420
650825037	407	70.91	24	407	3	386	0.0e+00	668	COG0192	S-adenosylmethionine synthetase	388
650825038	283	32.53	2	281	21	308	2.0e-56	212	COG1560	Lauroyl/myristoyl acyltransferase	308
650825039	296	38.41	8	296	20	307	4.0e-64	238	COG1560	Lauroyl/myristoyl acyltransferase	308
650825040	166	53.85	11	166	2	155	2.0e-54	205	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
650825041	246	33.48	19	240	11	224	7.0e-33	134	COG1040	Predicted amidophosphoribosyltransferases	225
650825044	795	31.36	22	772	8	706	3.0e-129	456	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
650825046	451	34.75	117	450	4	354	8.0e-74	271	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
650825047	438	35.33	2	438	1	436	0.0e+00	468	COG0621	tRNA A37 methylthiotransferase MiaB	437
650825049	319	48.89	1	315	2	300	7.0e-91	327	COG0223	Methionyl-tRNA formyltransferase	307
650825050	170	57.74	1	165	1	168	1.0e-57	215	COG0242	Peptide deformylase	168
650825051	389	39.1	8	383	4	350	1.0e-86	313	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
650825054	131	37.98	1	127	3	130	3.0e-22	97.7	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
650825055	312	32.11	11	300	1	294	2.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
650825056	204	29.31	4	175	3	176	2.0e-11	62.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650825057	140	27.1	21	116	18	124	1.0e-06	45.7	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
650825058	163	29.13	31	156	1	124	5.0e-11	60.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
650825060	338	31.58	1	259	1	261	3.0e-26	112	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650825061	424	29.15	1	418	8	433	4.0e-55	209	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
650825062	276	49.79	12	254	2	237	1.0e-77	283	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650825064	354	31.87	22	340	1	308	3.0e-37	149	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
650825065	309	32.04	1	308	3	297	2.0e-35	142	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650825066	265	42.86	12	263	2	250	4.0e-79	287	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650825067	658	35.41	16	620	17	611	2.0e-128	453	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
650825068	224	24.76	13	215	7	212	2.0e-20	92.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
650825069	320	38.05	1	317	2	317	3.0e-62	232	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650825070	431	52.37	11	431	1	413	0.0e+00	507	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
650825071	302	34.98	8	302	17	261	3.0e-47	182	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
650825072	256	40.67	52	256	39	243	6.0e-52	197	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
650825073	429	50.36	18	428	1	411	0.0e+00	504	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
650825074	248	16.26	2	215	60	304	2.0e-08	52.8	COG1216	Glycosyltransferase, GT2 family	305
650825076	446	47.15	1	440	4	459	6.0e-130	457	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
650825078	456	41.59	7	456	6	443	7.0e-113	401	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
650825079	257	60.16	3	253	2	252	1.0e-102	366	COG4598	ABC-type histidine transport system, ATPase component	256
650825080	270	33.96	9	270	18	275	5.0e-36	144	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650825081	237	46.43	12	234	5	228	2.0e-53	202	COG4215	ABC-type arginine transport system, permease component	230
650825082	225	43.24	2	223	1	222	2.0e-56	212	COG4160	ABC-type arginine/histidine transport system, permease component	228
650825083	331	45.18	6	329	19	347	4.0e-80	291	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
650825084	306	24.36	38	301	16	285	3.0e-38	152	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
650825085	343	35.13	1	340	1	350	2.0e-77	283	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
650825086	423	46.41	28	416	3	388	2.0e-115	409	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
650825088	332	46.89	11	332	2	319	3.0e-98	352	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
650825089	293	48.5	34	292	1	264	2.0e-35	143	COG0428	Zinc transporter ZupT	266
650825090	136	32.59	3	136	8	140	6.0e-19	86.6	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
650825091	463	34.89	6	431	3	422	4.0e-75	275	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
650825092	274	50.94	9	273	1	267	6.0e-92	330	COG0413	Ketopantoate hydroxymethyltransferase	268
650825093	278	51.44	3	275	1	278	1.0e-99	356	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
650825094	469	20.55	16	452	10	385	6.0e-12	65.6	COG2814	Predicted arabinose efflux permease, MFS family	394
650825095	70	37.14	1	70	4	72	9.0e-08	48.4	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
650825096	937	59.94	5	936	1	860	0.0e+00	1181	COG1048	Aconitase A	861
650825099	298	26.85	2	296	1	293	2.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
650825100	270	61.26	11	262	12	261	6.0e-98	350	COG4336	Uncharacterized protein YcsI, UPF0317 family	265
650825101	352	22.49	1	327	1	312	2.0e-27	116	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650825102	207	23.38	21	174	12	158	2.0e-08	53	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
650825103	427	37.47	49	426	3	378	9.0e-65	241	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650825105	447	36.34	4	446	8	467	1.0e-90	327	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
650825106	320	39.17	9	320	10	321	1.0e-65	243	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
650825107	677	38.87	21	675	5	640	6.0e-125	441	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
650825108	227	31.94	6	221	8	221	3.0e-32	131	COG1802	DNA-binding transcriptional regulator, GntR family	230
650825109	579	48.49	5	556	10	571	0.0e+00	617	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
650825110	275	43.92	2	254	3	257	4.0e-66	244	COG3622	Hydroxypyruvate isomerase	260
650825111	340	26.02	1	336	1	332	3.0e-32	132	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650825112	181	28.39	18	172	4	156	3.0e-10	58.4	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
650825113	430	34.05	57	428	8	377	2.0e-68	253	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650825115	227	19.4	27	227	2	201	1.0e-10	60	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650825116	385	42.12	11	356	6	336	4.0e-95	341	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
650825118	242	49.37	8	242	1	237	9.0e-77	280	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650825119	250	47.37	1	244	4	250	3.0e-76	278	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650825120	280	37.8	17	251	9	251	2.0e-40	159	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650825121	327	33.98	13	315	8	314	1.0e-39	156	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
650825122	300	36.75	23	298	13	293	5.0e-42	165	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650825123	425	26.37	39	399	6	358	7.0e-36	145	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650825124	500	38.03	1	496	10	527	2.0e-114	406	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650825125	390	37.53	1	390	1	393	4.0e-72	265	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650825126	460	22.55	6	375	5	372	1.0e-32	134	COG2079	2-methylcitrate dehydratase PrpD	453
650825127	433	33.26	1	432	1	403	1.0e-73	270	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
650825128	262	43.02	1	257	1	256	1.0e-57	216	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650825129	323	56.52	3	322	1	322	4.0e-124	438	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
650825130	322	42.81	4	318	23	342	3.0e-81	295	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
650825131	183	53.89	2	179	1	180	2.0e-57	215	COG2096	Cob(I)alamin adenosyltransferase	184
650825132	321	29.39	27	316	1	292	5.0e-32	131	COG0583	DNA-binding transcriptional regulator, LysR family	297
650825133	224	38.73	18	221	11	210	9.0e-44	170	COG0684	Regulator of RNase E activity RraA	210
650825134	337	39.08	1	324	3	316	9.0e-77	280	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
650825135	334	38.2	13	332	1	317	4.0e-73	268	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650825136	402	34.24	18	384	1	344	4.0e-72	265	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
650825142	402	15.11	65	393	59	384	9.0e-10	58.3	COG2814	Predicted arabinose efflux permease, MFS family	394
650825143	388	35.54	11	385	11	367	3.0e-64	239	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
650825144	403	22.55	30	395	35	380	4.0e-11	62.9	COG2814	Predicted arabinose efflux permease, MFS family	394
650825147	288	39.3	8	286	14	296	2.0e-58	219	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
650825148	272	43.67	1	245	2	246	1.0e-71	262	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
650825149	278	40.58	4	278	19	282	4.0e-49	188	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
650825150	258	43.75	2	254	27	282	6.0e-49	187	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
650825151	147	34.23	1	147	12	158	2.0e-20	92.1	COG2030	Acyl dehydratase	159
650825152	105	34.29	1	104	1	101	1.0e-11	61.6	COG0633	Ferredoxin	102
650825154	240	18.97	47	219	13	184	1.0e-09	57	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650825155	83	39.02	1	82	26	102	5.0e-09	52.7	COG0633	Ferredoxin	102
650825156	253	39.3	1	250	4	257	1.0e-45	176	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650825157	431	35.12	82	413	100	461	7.0e-59	221	COG0427	Acyl-CoA hydrolase	501
650825158	265	32.28	15	264	2	251	4.0e-31	128	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650825159	377	22.7	27	348	21	335	5.0e-28	118	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
650825160	281	35.34	141	253	3	118	5.0e-16	78.6	COG2030	Acyl dehydratase	159
650825161	355	29.71	2	350	24	390	2.0e-40	159	COG0183	Acetyl-CoA acetyltransferase	392
650825162	133	29.01	1	125	8	137	3.0e-16	77.7	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
650825163	256	41.7	5	252	1	250	2.0e-43	169	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650825165	323	35.4	1	319	1	317	1.0e-67	250	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650825166	536	34.51	9	533	12	528	1.0e-98	353	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650825167	388	38.89	1	388	1	393	9.0e-80	290	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650825168	410	37.72	10	398	3	394	7.0e-82	297	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650825169	318	31.52	6	158	7	171	1.0e-29	123	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
650825170	423	33.81	3	413	15	409	1.0e-67	250	COG2124	Cytochrome P450	411
650825171	251	42.97	1	247	1	249	6.0e-44	171	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650825173	323	20.34	22	304	3	287	3.0e-22	99.2	COG0668	Small-conductance mechanosensitive channel	316
650825174	525	29.63	126	232	3	109	3.0e-10	60.3	COG0607	Rhodanese-related sulfurtransferase	110
650825175	195	23.78	27	165	22	156	6.0e-08	50.8	COG5553	Predicted metal-dependent enzyme of the double-stranded beta helix superfamily	191
650825176	310	22.68	1	288	7	291	7.0e-19	88.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
650825177	236	39.57	8	232	2	229	1.0e-44	173	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650825178	434	23.73	112	417	15	326	8.0e-24	105	COG0642	Signal transduction histidine kinase	336
650825179	117	23.77	1	115	17	138	7.0e-03	32.6	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
650825180	349	31.64	19	288	4	271	5.0e-22	99.1	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
650825181	501	27.63	3	409	5	385	5.0e-33	136	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
650825183	320	37.14	8	316	4	317	3.0e-53	202	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650825184	250	38.52	1	247	2	250	5.0e-41	161	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650825185	579	34.54	18	567	3	537	1.0e-119	424	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
650825186	223	26.24	1	220	5	224	6.0e-35	140	COG1802	DNA-binding transcriptional regulator, GntR family	230
650825188	308	26.16	12	306	7	288	7.0e-17	81.6	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
650825189	336	38.19	1	335	26	357	8.0e-90	324	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
650825191	296	23.95	7	279	12	311	4.0e-15	75.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650825194	248	30.17	9	237	6	237	3.0e-35	141	COG1414	DNA-binding transcriptional regulator, IclR family	246
650825195	264	20.37	18	262	16	281	2.0e-13	69.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650825196	465	33.9	2	450	55	523	4.0e-90	325	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650825197	396	36.32	19	382	9	386	5.0e-67	248	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650825198	428	40.58	51	424	2	378	4.0e-69	255	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650825199	181	26.45	26	179	18	169	4.0e-12	64.6	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
650825200	329	23.87	1	323	1	322	4.0e-36	145	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650825201	159	35.67	1	155	2	156	2.0e-19	88.2	COG2030	Acyl dehydratase	159
650825204	267	29.06	136	250	11	127	5.0e-13	68.8	COG0526	Thiol-disulfide isomerase or thioredoxin	127
650825205	277	30.04	5	253	20	286	4.0e-20	92.3	COG0657	Acetyl esterase/lipase	312
650825206	399	40.71	4	391	1	377	1.0e-99	356	COG1454	Alcohol dehydrogenase, class IV	377
650825207	227	33.79	12	227	11	223	5.0e-27	114	COG1802	DNA-binding transcriptional regulator, GntR family	230
650825208	545	49.5	19	515	2	500	0.0e+00	567	COG1129	ABC-type sugar transport system, ATPase component	500
650825209	308	38.03	4	308	15	310	1.0e-48	187	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650825210	319	29.41	1	319	4	322	3.0e-44	172	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650825211	195	28.5	3	194	2	188	7.0e-27	113	COG0693	Putative intracellular protease/amidase	188
650825212	295	30.88	45	255	1	200	5.0e-30	125	COG0625	Glutathione S-transferase	211
650825213	228	30.26	1	223	1	227	2.0e-31	129	COG1011	FMN phosphatase YigB, HAD superfamily	229
650825214	205	23.74	1	197	6	201	1.0e-09	56.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650825217	436	34.41	59	429	10	376	5.0e-61	228	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650825218	196	22.29	16	179	2	161	1.0e-10	59.9	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
650825219	316	22.26	1	288	16	306	4.0e-37	148	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650825220	560	35.69	8	547	5	549	5.0e-107	382	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
650825221	702	36.13	7	695	1	674	0.0e+00	482	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
650825222	141	38.03	1	140	58	199	1.0e-31	128	COG5631	Predicted transcription regulator, contains HTH domain, MarR family	199
650825225	610	54.01	1	610	1	597	0.0e+00	773	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
650825226	172	36.24	11	159	7	154	3.0e-26	111	COG1522	DNA-binding transcriptional regulator, Lrp family	154
650825227	350	22.7	74	350	103	380	1.0e-23	104	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650825228	462	20.23	21	453	8	389	3.0e-12	66.8	COG2814	Predicted arabinose efflux permease, MFS family	394
650825229	457	56.21	1	456	2	458	0.0e+00	644	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
650825231	276	24.68	108	255	12	159	1.0e-08	54.2	COG1443	Isopentenyldiphosphate isomerase	185
650825232	372	34	20	266	16	237	4.0e-56	212	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
650825233	531	59.96	19	530	2	517	0.0e+00	577	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
650825236	291	33.78	66	290	10	205	3.0e-35	142	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
650825239	264	26.69	1	261	4	248	4.0e-25	108	COG3346	Cytochrome oxidase assembly protein ShyY1	252
650825240	213	21.86	15	209	1	206	3.0e-07	48.9	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
650825241	342	27.73	9	338	15	319	4.0e-40	158	COG1612	Heme A synthase	323
650825242	296	44.44	8	295	14	301	2.0e-76	279	COG0109	Polyprenyltransferase (heme O synthase)	304
650825243	200	38.34	10	200	13	204	4.0e-42	164	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
650825244	869	33.95	6	429	7	418	5.0e-55	210	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
650825245	293	38.51	1	292	42	332	3.0e-64	238	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
650825246	385	29.97	18	365	1	343	1.0e-42	167	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650825247	289	37.1	8	288	6	314	1.0e-64	239	COG0627	S-formylglutathione hydrolase FrmB	316
650825248	368	65.76	1	368	1	366	0.0e+00	562	COG1062	Zn-dependent alcohol dehydrogenase	366
650825250	409	30.17	5	398	51	437	1.0e-49	190	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
650825251	289	27.2	47	265	50	286	2.0e-20	93.4	COG0657	Acetyl esterase/lipase	312
650825252	284	29.25	4	284	10	258	4.0e-35	142	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
650825253	596	63.8	1	592	1	584	0.0e+00	911	COG0173	Aspartyl-tRNA synthetase	585
650825254	230	50.26	4	194	6	200	2.0e-57	215	COG2928	Uncharacterized membrane protein	222
650825255	101	46.67	1	75	8	81	9.0e-19	85.1	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
650825257	318	34.26	24	311	1	289	2.0e-43	169	COG0382	4-hydroxybenzoate polyprenyltransferase	289
650825258	398	44.27	8	397	65	455	1.0e-102	367	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
650825260	343	28.86	1	326	22	349	1.0e-37	150	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
650825261	203	25.59	5	203	34	244	3.0e-19	88.5	COG3751	Proline 4-hydroxylase (includes Rps23 Pro-64 3,4-dihydroxylase Tpa1), contains SM-20 domain	252
650825262	240	28.57	9	235	2	225	2.0e-35	142	COG1794	Aspartate/glutamate racemase	230
650825263	244	63.64	1	242	2	240	8.0e-105	373	COG1126	ABC-type polar amino acid transport system, ATPase component	240
650825264	229	40.97	3	229	4	222	2.0e-46	178	COG0765	ABC-type amino acid transport system, permease component	222
650825265	251	41.63	19	239	13	222	4.0e-45	174	COG0765	ABC-type amino acid transport system, permease component	222
650825266	299	31.05	1	271	2	271	3.0e-37	149	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650825267	332	50.3	1	328	1	319	9.0e-92	330	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
650825268	301	21.14	1	296	1	287	1.0e-18	87	COG0583	DNA-binding transcriptional regulator, LysR family	297
650825269	532	18.54	30	385	39	383	2.0e-13	71	COG2814	Predicted arabinose efflux permease, MFS family	394
650825270	310	48.52	4	305	2	298	1.0e-88	319	COG3246	Uncharacterized conserved protein, DUF849 family	298
650825271	260	38.61	5	254	1	248	2.0e-40	159	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650825272	239	30.87	4	233	6	230	9.0e-30	123	COG1802	DNA-binding transcriptional regulator, GntR family	230
650825273	463	46.24	4	452	3	453	0.0e+00	468	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
650825274	420	41.88	1	420	1	403	2.0e-94	339	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
650825275	161	22.46	11	145	6	138	4.0e-08	51	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650825276	733	38.96	404	725	4	324	6.0e-98	352	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
650825277	275	43.08	22	270	2	251	5.0e-43	168	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650825278	241	49.37	7	241	1	237	2.0e-84	305	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650825279	259	47.39	11	255	2	250	1.0e-77	283	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650825280	410	29.97	1	302	1	305	5.0e-40	158	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
650825281	313	33.54	1	313	3	294	4.0e-42	165	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650825282	412	23.18	17	379	2	359	4.0e-31	129	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650825283	244	41.04	2	241	1	250	4.0e-46	178	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650825284	241	39.06	9	237	7	236	2.0e-41	162	COG2186	DNA-binding transcriptional regulator, FadR family	241
650825285	531	41	1	530	5	538	0.0e+00	467	COG2303	Choline dehydrogenase or related flavoprotein	542
650825286	267	34.9	4	253	2	255	8.0e-56	210	COG0169	Shikimate 5-dehydrogenase	283
650825288	245	33.63	1	226	6	230	7.0e-34	137	COG1802	DNA-binding transcriptional regulator, GntR family	230
650825289	399	30.71	19	381	4	356	5.0e-43	168	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650825290	288	41.52	1	284	3	291	3.0e-43	168	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650825291	593	46.43	350	588	2	250	5.0e-70	258	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650825292	234	51.28	1	233	3	236	3.0e-89	321	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650825293	333	37.38	14	329	10	326	9.0e-74	270	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
650825294	253	43.63	1	251	1	251	4.0e-41	161	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650825295	328	40.62	9	328	5	326	9.0e-59	221	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
650825296	101	28.42	5	99	3	96	1.0e-11	61.4	COG5470	Uncharacterized conserved protein, DUF1330 family	96
650825297	263	30.94	1	262	1	262	5.0e-29	121	COG3971	2-keto-4-pentenoate hydratase	264
650825298	483	32.86	4	480	2	475	3.0e-77	283	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
650825299	443	42.12	1	439	6	465	4.0e-107	382	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
650825300	371	35.54	18	371	2	364	6.0e-57	214	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650825301	237	52.12	1	235	3	237	1.0e-80	292	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650825302	253	52.61	3	250	5	250	5.0e-85	307	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650825303	309	36.84	1	296	2	304	6.0e-43	168	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
650825304	291	42.57	1	290	3	297	2.0e-44	172	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650825305	353	35.91	12	344	1	331	5.0e-73	268	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650825306	442	26.73	7	384	1	400	5.0e-41	162	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
650825308	323	27.38	1	319	1	314	3.0e-35	142	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650825310	286	20.47	1	244	11	249	2.0e-08	53.8	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
650825311	298	30.54	8	297	1	296	2.0e-35	143	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
650825312	282	36.5	9	264	16	278	5.0e-47	181	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
650825315	356	37.16	24	350	1	322	1.0e-78	287	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
650825316	289	28.67	2	287	1	290	1.0e-36	146	COG0583	DNA-binding transcriptional regulator, LysR family	297
650825318	555	17.69	9	527	145	641	4.0e-46	179	COG4688	Uncharacterized protein	665
650825320	510	29.43	4	293	23	319	3.0e-45	176	COG3344	Retron-type reverse transcriptase	328
650825322	465	35.58	73	455	1	316	2.0e-69	256	COG2826	Transposase and inactivated derivatives, IS30 family	318
650825325	534	39.75	119	277	1	157	1.0e-25	111	COG3436	Transposase	157
650825327	669	19.66	1	576	1	559	2.0e-49	191	COG4688	Uncharacterized protein	665
650825330	162	48.21	2	162	1	167	2.0e-38	151	COG0629	Single-stranded DNA-binding protein	167
650825331	402	22.35	41	395	30	382	1.0e-18	88.3	COG2814	Predicted arabinose efflux permease, MFS family	394
650825332	948	63.71	1	948	3	935	0.0e+00	1517	COG0178	Excinuclease UvrABC ATPase subunit	935
650825333	375	42.72	4	372	9	409	8.0e-95	340	COG0232	dGTP triphosphohydrolase	412
650825334	362	55.74	1	355	1	356	4.0e-122	431	COG0337	3-dehydroquinate synthetase	360
650825335	198	47.9	28	194	4	169	1.0e-50	193	COG0703	Shikimate kinase	172
650825336	810	43.48	23	789	1	791	0.0e+00	794	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
650825338	420	46.19	6	395	3	394	5.0e-119	421	COG0019	Diaminopimelate decarboxylase	394
650825339	452	32.59	186	451	53	281	2.0e-26	114	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
650825340	685	27.83	25	443	1	346	7.0e-61	229	COG1333	Cytochrome c biogenesis protein ResB	478
650825341	233	35.97	18	156	6	121	7.0e-14	71.2	COG2863	Cytochrome c553	121
650825342	207	40.98	1	203	1	198	7.0e-55	207	COG0218	GTP-binding protein EngB required for normal cell division	200
650825343	337	62.01	9	337	4	330	0.0e+00	510	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
650825344	68	51.47	1	68	1	68	3.0e-17	80	COG3360	Flavin-binding protein dodecin	71
650825345	678	37.91	29	660	2	566	2.0e-113	403	COG4232	Thiol:disulfide interchange protein	569
650825346	109	48.04	6	107	2	103	1.0e-26	111	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
650825347	127	75.86	1	116	1	116	2.0e-45	174	COG0203	Ribosomal protein L17	116
650825348	329	52.2	6	323	1	313	7.0e-97	347	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
650825350	154	56.13	1	154	51	205	5.0e-46	177	COG0522	Ribosomal protein S4 or related protein	205
650825351	133	64.66	1	133	1	129	2.0e-45	174	COG0100	Ribosomal protein S11	129
650825352	121	59.5	1	120	1	121	2.0e-37	147	COG0099	Ribosomal protein S13	121
650825353	37	65.79	1	37	1	38	1.0e-04	38.6	COG0257	Ribosomal protein L36	38
650825354	72	66.67	1	72	1	72	2.0e-25	107	COG0361	Translation initiation factor IF-1	75
650825355	441	50.94	13	429	15	432	2.0e-129	455	COG0201	Preprotein translocase subunit SecY	436
650825356	146	53.42	5	144	2	147	2.0e-30	124	COG0200	Ribosomal protein L15	152
650825357	61	54.55	6	60	1	55	6.0e-12	62.4	COG1841	Ribosomal protein L30/L7E	55
650825358	173	56.71	11	173	17	180	1.0e-51	196	COG0098	Ribosomal protein S5	181
650825359	121	50.82	1	121	6	125	1.0e-25	108	COG0256	Ribosomal protein L18	125
650825360	177	49.43	1	176	1	176	5.0e-57	213	COG0097	Ribosomal protein L6P/L9E	178
650825361	131	59.54	1	130	1	131	2.0e-47	181	COG0096	Ribosomal protein S8	132
650825362	101	57.38	41	101	1	61	5.0e-16	76	COG0199	Ribosomal protein S14	61
650825363	179	64.25	1	179	1	179	2.0e-72	265	COG0094	Ribosomal protein L5	180
650825364	106	54.29	1	103	2	104	6.0e-17	79.2	COG0198	Ribosomal protein L24	104
650825365	122	70.49	1	122	1	122	2.0e-47	181	COG0093	Ribosomal protein L14	122
650825366	475	41.7	6	473	2	466	0.0e+00	498	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650825367	432	34.42	5	423	3	388	7.0e-69	254	COG0183	Acetyl-CoA acetyltransferase	392
650825368	654	42.51	309	583	4	289	4.0e-70	259	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
650825369	552	37.8	18	552	4	522	0.0e+00	472	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650825370	93	57.5	12	91	7	86	4.0e-22	96.1	COG0186	Ribosomal protein S17	87
650825371	63	50	2	63	4	65	9.0e-08	48.3	COG0255	Ribosomal protein L29	69
650825372	138	63.24	1	134	2	137	1.0e-47	181	COG0197	Ribosomal protein L16/L10AE	146
650825373	267	55.65	12	240	1	230	4.0e-79	288	COG0092	Ribosomal protein S3	233
650825374	109	60.19	1	108	9	116	9.0e-32	128	COG0091	Ribosomal protein L22	120
650825375	91	71.43	1	91	1	91	3.0e-36	143	COG0185	Ribosomal protein S19	93
650825376	275	58.55	1	274	1	275	2.0e-105	375	COG0090	Ribosomal protein L2	275
650825377	98	56.52	6	96	1	92	7.0e-22	95.3	COG0089	Ribosomal protein L23	94
650825378	206	40.95	1	206	2	211	1.0e-53	203	COG0088	Ribosomal protein L4	214
650825379	229	54.79	12	229	1	218	5.0e-73	267	COG0087	Ribosomal protein L3	218
650825381	654	54.38	373	646	12	283	2.0e-95	343	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
650825382	398	24.02	12	391	11	385	5.0e-14	72.5	COG2814	Predicted arabinose efflux permease, MFS family	394
650825383	103	75.73	1	103	1	103	4.0e-39	152	COG0051	Ribosomal protein S10	104
650825384	397	83.38	1	397	1	394	0.0e+00	700	COG0050	Translation elongation factor EF-Tu, a GTPase	394
650825385	700	66.29	1	700	1	693	0.0e+00	1005	COG0480	Translation elongation factor EF-G, a GTPase	697
650825386	156	60.81	2	149	1	148	2.0e-55	208	COG0049	Ribosomal protein S7	148
650825388	235	39.91	1	226	1	226	2.0e-47	182	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650825389	368	23.17	34	335	1	324	1.0e-29	124	COG4254	Uncharacterized conserved protein, contains LysM and FecR  domains	339
650825390	651	25.25	12	379	1	400	4.0e-44	173	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
650825391	1415	48.51	13	853	1	808	0.0e+00	868	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
650825393	126	66.67	1	126	1	124	3.0e-22	97.2	COG0222	Ribosomal protein L7/L12	124
650825394	174	42.86	1	173	1	175	4.0e-35	141	COG0244	Ribosomal protein L10	175
650825395	231	59.65	1	227	1	228	1.0e-76	279	COG0081	Ribosomal protein L1	228
650825396	143	71.13	2	143	1	141	2.0e-51	195	COG0080	Ribosomal protein L11	141
650825397	177	59.09	1	176	1	176	7.0e-53	199	COG0250	Transcription antitermination factor NusG	178
650825398	126	32.39	48	118	1	71	1.0e-08	51.9	COG0690	Preprotein translocase subunit SecE	73
650825400	397	83.38	1	397	1	394	0.0e+00	700	COG0050	Translation elongation factor EF-Tu, a GTPase	394
650825404	436	52.24	1	436	1	446	4.0e-126	445	COG2031	Short chain fatty acids transporter	446
650825405	306	39.92	39	274	6	225	7.0e-33	134	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
650825406	268	40.78	6	258	4	257	2.0e-58	219	COG1192	Cellulose biosynthesis protein BcsQ	259
650825407	223	35.81	6	215	1	208	3.0e-43	168	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
650825408	638	63.72	3	635	1	621	0.0e+00	963	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
650825409	68	65.15	3	68	2	67	5.0e-24	102	COG1278	Cold shock protein, CspA family	67
650825410	389	32.98	18	387	21	386	1.0e-81	296	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
650825411	209	31.58	17	187	14	172	3.0e-18	85	COG2184	Fido, protein-threonine AMPylation domain	201
650825413	488	46.63	3	488	1	454	0.0e+00	508	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
650825414	98	31.52	1	90	1	91	8.0e-12	61.8	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
650825416	477	61.51	2	475	14	490	0.0e+00	724	COG0753	Catalase	496
650825417	237	49.37	3	237	1	237	2.0e-77	281	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650825418	247	44.98	1	245	2	250	7.0e-74	270	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650825419	337	39.37	13	320	1	314	8.0e-44	171	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
650825420	306	37.22	1	303	1	292	3.0e-35	142	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650825421	400	30.68	29	384	2	365	6.0e-45	175	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650825422	264	41.57	1	261	1	251	7.0e-36	144	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650825424	525	34.04	23	512	15	529	1.0e-97	350	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650825425	330	40	4	327	2	317	1.0e-74	273	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650825426	247	25	9	246	1	240	3.0e-31	128	COG1414	DNA-binding transcriptional regulator, IclR family	246
650825427	565	41.25	273	565	6	306	3.0e-68	253	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
650825428	152	34.75	35	152	1	110	6.0e-10	56.8	COG0594	RNase P protein component	117
650825430	466	46.49	7	462	1	408	3.0e-123	435	COG0593	Chromosomal replication initiation ATPase DnaA	408
650825431	369	40.11	7	369	6	364	2.0e-81	296	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
650825432	816	60	13	574	6	562	0.0e+00	872	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
650825433	254	31.5	32	230	10	209	1.0e-34	140	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
650825434	454	46.74	7	449	7	442	4.0e-98	352	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
650825435	190	32.77	1	177	1	175	7.0e-31	126	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
650825436	354	37.22	1	352	4	355	4.0e-82	298	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
650825442	386	21.74	13	380	16	322	3.0e-33	136	COG0598	Mg2+ and Co2+ transporter CorA	322
650825443	169	56.29	1	167	26	191	1.0e-51	195	COG3812	Uncharacterized protein	193
650825444	318	35.2	5	318	4	319	1.0e-58	220	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650825446	495	51.83	1	492	1	492	0.0e+00	512	COG3333	TctA family transporter	504
650825448	235	26.53	9	233	16	254	3.0e-31	128	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
650825449	334	43.15	1	334	4	338	3.0e-92	331	COG2130	NADPH-dependent curcumin reductase CurA	340
650825450	63	56.9	1	58	14	71	3.0e-19	86.9	COG3530	Uncharacterized conserved protein, DUF3820 family	71
650825451	300	32.35	57	294	44	272	8.0e-35	140	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
650825452	141	51.75	1	141	1	143	5.0e-43	166	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
650825453	201	46.81	16	198	1	188	3.0e-67	247	COG2818	3-methyladenine DNA glycosylase Tag	188
650825454	224	30.73	17	216	1	201	1.0e-20	93.7	COG0625	Glutathione S-transferase	211
650825455	581	40.22	35	571	28	574	0.0e+00	517	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
650825456	84	35.38	1	65	1	65	6.0e-08	49.2	COG2608	Copper chaperone CopZ	71
650825458	271	44.92	20	255	4	238	2.0e-68	252	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
650825460	128	38.68	7	110	2	106	1.0e-22	98.5	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
650825461	810	59.06	1	806	1	791	0.0e+00	1119	COG1251	NAD(P)H-nitrite reductase, large subunit	793
650825462	286	50.78	4	261	3	248	2.0e-87	315	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
650825463	257	35.43	3	252	6	250	1.0e-43	170	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
650825464	435	27.4	28	377	1	335	7.0e-48	185	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
650825466	387	39.2	9	374	1	351	5.0e-72	265	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
650825468	270	37.73	8	270	2	274	7.0e-43	167	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650825469	220	47.69	2	216	6	221	2.0e-55	208	COG0765	ABC-type amino acid transport system, permease component	222
650825470	290	31.6	3	286	2	261	1.0e-41	163	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
650825471	296	25.61	33	276	48	276	3.0e-05	43	COG5006	Threonine/homoserine efflux transporter RhtA	292
650825472	396	45.25	1	396	7	401	0.0e+00	462	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
650825473	321	32.71	1	320	1	319	2.0e-62	232	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650825474	688	15.22	13	333	1	288	7.0e-11	62.7	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
650825475	272	27.53	26	271	1	246	1.0e-34	140	COG1414	DNA-binding transcriptional regulator, IclR family	246
650825476	719	46.17	254	719	105	544	0.0e+00	523	COG2225	Malate synthase	545
650825477	305	28.33	6	299	5	297	1.0e-36	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
650825478	246	32.7	21	229	10	219	5.0e-33	134	COG1802	DNA-binding transcriptional regulator, GntR family	230
650825479	242	30.13	7	241	8	238	5.0e-28	118	COG3473	Maleate cis-trans isomerase	238
650825480	433	36.05	52	430	1	376	8.0e-68	251	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650825481	207	21.01	22	158	22	159	3.0e-09	55.3	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
650825482	351	25.17	1	277	2	280	2.0e-26	113	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650825483	467	36.42	5	455	1	430	5.0e-95	341	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
650825484	256	41.11	6	250	19	266	5.0e-62	231	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
650825485	167	51.01	6	153	4	151	1.0e-48	185	COG3194	Ureidoglycolate hydrolase (allantoin degradation)	168
650825486	175	52.2	13	171	10	168	8.0e-48	183	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
650825487	493	53.23	1	490	4	493	0.0e+00	615	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
650825488	781	58.4	3	775	1	774	0.0e+00	1108	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
650825489	268	30.04	3	267	2	257	7.0e-39	154	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
650825490	447	33.09	42	443	22	420	5.0e-77	281	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
650825491	346	56.06	15	343	6	334	7.0e-129	453	COG4266	Allantoicase	334
650825492	312	24.51	5	304	2	267	3.0e-30	125	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
650825493	117	52.99	1	117	8	124	4.0e-44	169	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
650825494	412	44.1	1	408	1	399	3.0e-102	365	COG3748	Uncharacterized membrane protein	407
650825495	95	48.24	11	95	12	96	1.0e-27	114	COG2154	Pterin-4a-carbinolamine dehydratase	101
650825496	313	34.39	1	312	2	311	6.0e-34	138	COG0679	Predicted permease	311
650825497	499	25.57	219	477	1	233	2.0e-39	157	COG0775	Nucleoside phosphorylase	234
650825498	181	41.52	16	181	3	170	5.0e-34	137	COG3613	Nucleoside 2-deoxyribosyltransferase	172
650825499	343	36.73	1	340	2	332	3.0e-79	289	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650825500	432	39.9	51	431	1	379	1.0e-71	264	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650825501	176	26.8	24	176	9	159	4.0e-17	81.1	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
650825503	581	51.25	9	564	1	543	0.0e+00	605	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
650825504	905	55.81	36	900	2	853	0.0e+00	1071	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
650825505	198	45.39	39	190	4	154	5.0e-36	144	COG1522	DNA-binding transcriptional regulator, Lrp family	154
650825506	326	42.12	1	326	1	330	9.0e-85	307	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650825507	164	29.73	1	148	2	149	5.0e-17	80.8	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
650825508	424	46.42	45	421	1	377	9.0e-94	337	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650825509	894	32.59	3	627	1	569	0.0e+00	465	COG0550	DNA topoisomerase IA	570
650825510	863	23.03	690	860	10	187	9.0e-19	89.6	COG4929	Uncharacterized membrane-anchored protein	190
650825512	153	36.94	1	153	1	157	1.0e-19	89.6	COG2922	Uncharacterized conserved protein Smg, DUF494 family	157
650825513	672	54.83	1	672	1	645	0.0e+00	814	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
650825514	535	45.52	12	535	1	526	0.0e+00	648	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
650825515	393	43.6	2	393	1	392	7.0e-80	291	COG0183	Acetyl-CoA acetyltransferase	392
650825516	627	44.37	16	608	3	573	0.0e+00	653	COG4579	Isocitrate dehydrogenase kinase/phosphatase	578
650825517	392	41.58	6	388	1	387	4.0e-94	338	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650825518	129	28.46	6	126	1	121	8.0e-14	69.4	COG0789	DNA-binding transcriptional regulator, MerR family	124
650825519	356	23.77	52	295	31	236	5.0e-19	89.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650825520	233	35.5	25	223	19	216	2.0e-26	112	COG1802	DNA-binding transcriptional regulator, GntR family	230
650825521	422	40.66	13	408	3	396	5.0e-106	378	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650825522	524	35.63	9	503	5	507	2.0e-102	366	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
650825524	533	37.5	17	526	13	519	3.0e-109	389	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
650825526	274	36.76	1	272	15	285	1.0e-55	210	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
650825527	325	26.96	9	323	5	318	4.0e-44	172	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
650825528	629	40.42	12	624	20	638	2.0e-110	393	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
650825529	569	31.68	14	557	3	530	2.0e-104	373	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
650825530	497	45.17	17	489	1	468	0.0e+00	473	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650825531	236	33.78	10	233	1	223	2.0e-28	119	COG1802	DNA-binding transcriptional regulator, GntR family	230
650825532	336	25.75	1	327	4	321	4.0e-29	122	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
650825533	266	45.67	9	259	2	248	2.0e-76	278	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
650825534	292	31.75	41	291	11	258	4.0e-39	155	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
650825535	254	25.2	12	253	3	252	3.0e-04	38.8	COG0730	Uncharacterized membrane protein YfcA	258
650825536	208	49.26	8	208	7	208	7.0e-24	103	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
650825537	399	39	8	397	7	396	3.0e-103	369	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
650825538	209	19.7	12	201	47	243	1.0e-07	49.8	COG1651	Protein-disulfide isomerase	244
650825539	232	19.39	1	231	1	260	3.0e-13	68.9	COG3087	Cell division protein FtsN	264
650825540	561	39.59	6	561	4	577	0.0e+00	525	COG0018	Arginyl-tRNA synthetase	577
650825541	1276	17.85	378	962	37	677	2.0e-08	56	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
650825544	266	41.64	5	266	13	281	2.0e-50	193	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650825545	293	38.78	1	293	1	294	3.0e-58	218	COG1175	ABC-type sugar transport system, permease component	295
650825546	431	30.45	1	430	4	433	1.0e-42	167	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650825547	354	49.71	1	340	1	336	1.0e-115	409	COG3839	ABC-type sugar transport system, ATPase component	338
650825548	264	29.09	1	264	1	265	8.0e-28	117	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
650825549	349	37.24	10	335	1	331	5.0e-68	251	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650825550	567	32.36	33	440	3	383	7.0e-94	338	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
650825552	454	43.33	1	446	15	441	7.0e-103	367	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
650825553	87	46.94	1	49	1	49	5.0e-09	52.6	COG2906	Bacterioferritin-associated ferredoxin	63
650825555	158	66.03	1	156	1	156	1.0e-58	218	COG2193	Bacterioferritin (cytochrome b1)	157
650825557	535	59.58	1	526	3	528	0.0e+00	765	COG4108	Peptide chain release factor RF-3	528
650825558	209	40.2	1	203	1	204	8.0e-30	123	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
650825559	477	41.08	1	477	25	500	4.0e-116	411	COG0513	Superfamily II DNA and RNA helicase	513
650825560	203	43.55	1	186	1	179	2.0e-51	195	COG1704	Uncharacterized conserved protein	185
650825561	297	42.42	1	297	4	271	8.0e-53	200	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
650825566	83	48.78	1	81	1	82	6.0e-06	42.3	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
650825567	529	29.87	4	511	13	534	1.0e-69	257	COG0747	ABC-type transport system, periplasmic component	556
650825568	193	29.51	17	190	1	178	4.0e-18	85	COG1514	2'-5' RNA ligase	180
650825572	240	31.44	22	214	3	194	6.0e-30	124	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
650825574	304	24.91	46	304	37	290	1.0e-03	37.6	COG5006	Threonine/homoserine efflux transporter RhtA	292
650825575	311	28.67	34	311	40	324	1.0e-51	196	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
650825577	249	31.88	1	224	4	230	2.0e-34	139	COG2186	DNA-binding transcriptional regulator, FadR family	241
650825578	529	37.21	74	522	2	469	1.0e-87	317	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
650825579	405	28.93	19	368	2	349	1.0e-32	134	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650825580	296	39	1	295	4	296	2.0e-46	179	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650825581	323	39.61	19	314	7	314	7.0e-43	168	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
650825582	244	40.16	1	236	2	250	4.0e-64	238	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650825583	244	43.57	3	242	1	237	9.0e-62	230	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650825584	701	23.41	2	699	29	768	2.0e-42	167	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
650825585	812	42.45	14	810	1	773	0.0e+00	742	COG4993	Glucose dehydrogenase	773
650825588	333	28.96	3	324	71	402	6.0e-28	118	COG3464	Transposase	402
650825591	255	61.02	1	253	1	254	2.0e-89	322	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
650825592	160	37.89	1	160	3	155	3.0e-33	134	COG2969	Stringent starvation protein B	155
650825593	216	37.13	16	206	1	201	2.0e-30	126	COG0625	Glutathione S-transferase	211
650825594	281	31.84	18	281	21	250	1.0e-45	177	COG2857	Cytochrome c1	250
650825595	462	45.73	10	441	5	372	1.0e-88	320	COG1290	Cytochrome b subunit of the bc complex	381
650825596	214	33.85	21	211	9	170	4.0e-27	114	COG0723	Rieske Fe-S protein	177
650825597	153	46.62	6	153	2	129	3.0e-33	134	COG1970	Large-conductance mechanosensitive channel	130
650825598	258	36.86	7	258	4	250	2.0e-58	219	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
650825599	381	44.74	36	375	16	341	2.0e-69	256	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
650825600	268	47.86	3	256	1	255	3.0e-55	208	COG0805	Sec-independent protein secretion pathway component TatC	255
650825601	156	29.79	1	94	1	94	7.0e-12	63.4	COG1826	Sec-independent protein translocase protein TatA	94
650825602	76	29.33	1	75	1	75	4.0e-13	66.1	COG1826	Sec-independent protein translocase protein TatA	94
650825603	122	43.52	3	110	1	104	2.0e-25	107	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
650825604	115	51.09	10	101	1	89	2.0e-21	94.5	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
650825605	134	57.66	1	111	1	111	1.0e-43	168	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
650825606	267	65.76	10	266	1	256	1.0e-111	396	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
650825607	247	51.44	1	243	2	240	5.0e-80	290	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
650825608	217	43.84	1	217	1	204	2.0e-67	248	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
650825609	195	58.97	1	195	3	195	8.0e-80	289	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
650825610	438	55.01	4	431	1	421	0.0e+00	545	COG0141	Histidinol dehydrogenase	425
650825611	224	50.24	10	216	3	208	1.0e-57	216	COG0040	ATP phosphoribosyltransferase	290
650825612	421	64.13	1	419	1	421	0.0e+00	603	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
650825613	82	42.31	3	79	1	78	2.0e-21	93.8	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
650825614	264	20	38	257	45	253	2.0e-10	59.8	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
650825615	267	42.91	3	267	1	252	4.0e-67	247	COG1131	ABC-type multidrug transport system, ATPase component	293
650825616	219	33.67	21	214	5	198	8.0e-34	137	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
650825617	285	38.4	10	254	1	244	4.0e-58	218	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
650825619	262	47.13	2	262	6	265	4.0e-59	221	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
650825620	275	52.14	7	262	5	261	6.0e-89	320	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
650825621	61	40	1	59	7	66	6.0e-11	59.2	COG1724	Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family	66
650825622	138	37.7	5	65	4	64	1.0e-06	45.4	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
650825624	487	44.26	23	485	2	457	0.0e+00	487	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
650825625	1498	57.8	652	1167	5	483	0.0e+00	666	COG0069	Glutamate synthase domain 2	485
650825630	211	37.85	2	209	1	211	8.0e-31	127	COG0625	Glutathione S-transferase	211
650825631	312	29.9	6	293	2	287	1.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
650825632	203	39.05	1	202	2	205	2.0e-34	139	COG2085	Predicted dinucleotide-binding enzyme	211
650825633	324	41.54	4	324	3	326	1.0e-65	243	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
650825637	445	29.69	12	429	1	369	7.0e-43	168	COG1680	CubicO group peptidase, beta-lactamase class C family	390
650825639	805	37.82	11	320	3	304	4.0e-71	263	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
650825640	398	42.01	7	398	4	392	3.0e-82	299	COG0183	Acetyl-CoA acetyltransferase	392
650825641	273	23.51	16	261	22	287	8.0e-20	90.9	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
650825642	193	50.54	1	184	1	172	2.0e-55	208	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
650825643	307	45.89	1	292	1	267	4.0e-77	281	COG1091	dTDP-4-dehydrorhamnose reductase	281
650825644	518	40.89	35	505	3	445	2.0e-111	396	COG0166	Glucose-6-phosphate isomerase	446
650825645	85	60.56	1	71	1	71	2.0e-21	93.7	COG0361	Translation initiation factor IF-1	75
650825646	297	21.92	2	289	4	277	9.0e-05	41.3	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
650825647	340	64.86	2	333	1	318	0.0e+00	531	COG1088	dTDP-D-glucose 4,6-dehydratase	340
650825648	407	17.72	19	407	41	423	3.0e-14	73.3	COG3307	O-antigen ligase	424
650825649	375	22.76	1	367	1	381	2.0e-22	100	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650825650	424	25.65	1	423	6	415	7.0e-10	59	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
650825651	472	46.02	4	335	2	333	3.0e-117	415	COG0836	Mannose-1-phosphate guanylyltransferase	333
650825653	643	28.83	15	403	13	381	5.0e-27	116	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650825654	346	62.83	4	339	3	341	0.0e+00	531	COG1089	GDP-D-mannose dehydratase	345
650825655	296	30.6	4	296	3	313	2.0e-31	129	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650825656	382	24.87	1	382	1	381	5.0e-32	132	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650825657	265	35.91	7	265	11	263	6.0e-40	158	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
650825658	406	47.01	1	247	1	249	5.0e-83	301	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
650825660	1066	23.5	12	408	9	381	3.0e-28	121	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650825666	532	40	116	274	2	157	1.0e-24	108	COG3436	Transposase	157
650825669	554	44.38	139	297	1	157	8.0e-28	119	COG3436	Transposase	157
650825675	313	20.31	1	256	1	249	3.0e-19	89.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
650825677	291	57.09	3	291	1	286	1.0e-114	406	COG1209	dTDP-glucose pyrophosphorylase	286
650825678	357	61.36	1	351	1	339	0.0e+00	536	COG1088	dTDP-D-glucose 4,6-dehydratase	340
650825680	459	47.77	229	452	1	218	3.0e-65	242	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
650825682	298	22.82	1	296	1	287	3.0e-25	109	COG0583	DNA-binding transcriptional regulator, LysR family	297
650825683	312	51.29	1	308	21	319	7.0e-84	304	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
650825684	332	32.82	9	330	2	317	7.0e-49	188	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650825686	423	25	48	419	37	406	1.0e-31	131	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
650825687	108	27.55	4	101	3	96	2.0e-05	40.8	COG3668	Plasmid stabilization system protein ParE	98
650825691	329	36.99	10	326	1	317	4.0e-66	245	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650825692	224	32.38	11	219	11	204	8.0e-26	110	COG0684	Regulator of RNase E activity RraA	210
650825693	312	26.13	5	309	7	293	1.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
650825694	268	33.46	4	267	1	255	1.0e-40	160	COG1712	Predicted dinucleotide-utilizing enzyme	255
650825695	261	36.4	3	257	1	250	1.0e-32	133	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650825698	684	43.53	29	668	1	588	0.0e+00	630	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
650825699	398	42.23	1	386	2	371	1.0e-112	400	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
650825700	198	46.52	1	182	39	225	3.0e-59	221	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
650825701	377	22.22	1	365	1	366	2.0e-26	113	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650825703	458	25.11	42	446	11	435	5.0e-38	152	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
650825704	382	25.32	5	378	3	378	9.0e-31	128	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650825705	630	29.97	1	601	1	517	3.0e-98	352	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
650825706	376	26.51	10	370	4	376	2.0e-33	136	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650825707	412	18.18	14	392	1	352	4.0e-08	53	COG2327	Polysaccharide pyruvyl transferase family protein WcaK	385
650825708	490	26.4	1	472	1	480	8.0e-21	95.6	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
650825709	743	26.53	13	477	4	458	5.0e-46	179	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
650825710	147	33.79	1	144	2	139	5.0e-30	123	COG0394	Protein-tyrosine-phosphatase	139
650825711	372	36.97	73	283	45	239	2.0e-36	147	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
650825714	272	38.52	2	268	49	317	1.0e-52	200	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650825715	293	25	23	290	6	279	7.0e-34	137	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
650825716	383	26.77	6	378	1	390	5.0e-46	178	COG0183	Acetyl-CoA acetyltransferase	392
650825717	696	42.25	294	573	2	285	1.0e-80	294	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
650825718	244	30.59	30	244	16	228	3.0e-21	95.5	COG1802	DNA-binding transcriptional regulator, GntR family	230
650825719	414	41.88	17	410	7	396	1.0e-103	370	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650825720	519	36.4	2	514	3	511	3.0e-91	329	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
650825723	800	24.65	233	800	77	577	1.0e-34	142	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
650825724	173	53.76	1	173	2	174	1.0e-57	215	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
650825726	308	24.9	55	294	45	276	4.0e-08	52.6	COG5006	Threonine/homoserine efflux transporter RhtA	292
650825727	332	31.78	2	312	1	313	2.0e-55	209	COG0859	ADP-heptose:LPS heptosyltransferase	334
650825728	661	51.18	1	550	6	537	0.0e+00	611	COG1292	Choline-glycine betaine transporter	537
650825729	444	33.41	3	437	2	417	7.0e-89	321	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
650825730	159	52.26	1	153	2	151	3.0e-54	204	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
650825731	501	40.52	1	488	1	484	5.0e-71	262	COG0591	Na+/proline symporter	493
650825732	297	29.89	25	297	1	279	6.0e-51	194	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
650825733	384	45.53	1	379	20	396	2.0e-113	402	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650825734	262	35.06	10	257	8	256	2.0e-37	149	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650825735	272	26.41	1	270	2	281	6.0e-24	104	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650825736	332	37.61	1	332	1	331	3.0e-81	295	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650825737	157	36.49	1	148	5	152	2.0e-18	85.4	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
650825738	421	44.65	48	421	1	374	7.0e-86	311	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650825739	255	33.63	9	233	2	226	9.0e-36	143	COG1802	DNA-binding transcriptional regulator, GntR family	230
650825740	144	32.61	9	144	1	136	7.0e-23	99.6	COG0824	Acyl-CoA thioesterase FadM	137
650825741	279	57.51	1	272	1	272	4.0e-112	397	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
650825743	285	25.29	1	249	1	232	1.0e-27	116	COG1521	Pantothenate kinase type III	251
650825744	291	30.89	32	285	1	236	1.0e-36	147	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
650825745	214	34.62	4	211	3	204	4.0e-39	154	COG2945	Alpha/beta superfamily hydrolase	210
650825746	418	43.97	50	418	15	386	8.0e-102	364	COG1686	D-alanyl-D-alanine carboxypeptidase	389
650825747	287	34.04	8	285	1	281	7.0e-48	184	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
650825748	94	38.37	9	94	5	90	4.0e-22	96.5	COG2921	Putative lipoic acid-binding regulatory protein	90
650825749	225	45.33	8	220	16	211	1.0e-64	239	COG0321	Lipoate-protein ligase B	221
650825750	261	33.59	2	258	1	257	4.0e-48	184	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650825751	330	63.31	25	330	1	306	0.0e+00	482	COG0320	Lipoate synthase	306
650825752	306	28.52	1	290	1	284	6.0e-26	111	COG0583	DNA-binding transcriptional regulator, LysR family	297
650825753	538	30.97	16	521	31	536	2.0e-73	270	COG0747	ABC-type transport system, periplasmic component	556
650825754	325	42.99	1	320	1	315	7.0e-81	294	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
650825755	315	46.88	28	315	5	286	6.0e-68	251	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
650825756	327	53.14	7	322	1	315	6.0e-118	417	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
650825757	344	45.45	5	322	3	266	7.0e-94	337	COG4608	ABC-type oligopeptide transport system, ATPase component	309
650825758	377	25.52	24	377	26	407	3.0e-31	129	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
650825759	308	26.76	5	299	1	297	2.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
650825760	251	39.06	5	249	3	251	6.0e-43	167	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650825761	282	47.93	2	243	3	243	3.0e-84	305	COG3959	Transketolase, N-terminal subunit	243
650825762	333	47.21	29	332	10	312	3.0e-101	361	COG3958	Transketolase, C-terminal subunit	312
650825763	322	43.73	1	321	1	327	4.0e-87	314	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650825764	178	29.82	8	178	2	172	5.0e-17	80.8	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
650825765	419	47.59	46	419	1	373	6.0e-82	298	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650825766	283	38.41	1	274	11	285	2.0e-60	226	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
650825767	390	47.37	8	386	4	377	2.0e-105	376	COG1454	Alcohol dehydrogenase, class IV	377
650825768	487	47.39	1	477	3	470	0.0e+00	516	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650825769	293	26.38	3	285	10	312	2.0e-26	112	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
650825770	237	29.72	9	220	1	212	1.0e-38	153	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
650825771	490	21.82	2	347	34	406	3.0e-20	93.7	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
650825772	527	32.06	1	508	4	534	6.0e-84	305	COG0747	ABC-type transport system, periplasmic component	556
650825773	308	46.89	1	304	19	317	6.0e-81	294	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
650825774	283	47.5	1	280	15	285	8.0e-68	250	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
650825775	327	52.68	9	322	1	314	1.0e-116	413	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
650825776	338	46.25	18	320	1	263	1.0e-90	327	COG4608	ABC-type oligopeptide transport system, ATPase component	309
650825777	286	34.86	7	286	2	267	6.0e-43	168	COG3741	N-formylglutamate amidohydrolase	272
650825779	297	30	20	294	5	280	4.0e-38	152	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
650825780	441	42.95	1	439	10	445	0.0e+00	489	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
650825784	100	35.96	11	98	19	106	4.0e-12	63.1	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
650825785	443	65.01	4	443	2	444	0.0e+00	653	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
650825786	177	66.86	3	177	1	175	9.0e-74	269	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
650825787	331	39.81	10	331	7	330	1.0e-85	309	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650825789	427	48.29	47	427	2	379	8.0e-86	311	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650825790	287	38.03	2	285	5	287	1.0e-70	259	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
650825791	185	30.73	5	182	47	223	1.0e-17	82.8	COG1802	DNA-binding transcriptional regulator, GntR family	230
650825794	330	34.62	16	326	7	317	1.0e-58	220	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650825795	139	32.33	6	138	9	139	1.0e-19	88.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
650825796	399	23.4	23	397	27	392	1.0e-09	57.9	COG2814	Predicted arabinose efflux permease, MFS family	394
650825797	557	42.94	1	536	3	523	0.0e+00	524	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
650825798	269	41.98	3	262	5	265	5.0e-65	241	COG2162	Arylamine N-acetyltransferase	275
650825799	147	54.17	29	147	1	120	4.0e-22	97.4	COG1734	RNA polymerase-binding transcription factor DksA	120
650825800	368	39.72	11	367	1	321	1.0e-86	313	COG0523	GTPase, G3E family	323
650825802	156	34.31	16	152	5	140	8.0e-28	116	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
650825804	238	40.09	4	229	3	234	8.0e-64	237	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
650825805	301	40.74	10	278	7	272	6.0e-37	147	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
650825806	363	30.88	19	358	2	303	6.0e-67	247	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
650825807	316	48.42	3	315	5	299	9.0e-85	306	COG4973	Site-specific recombinase XerC	299
650825808	229	33.94	5	220	2	217	1.0e-30	126	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
650825809	290	50.18	1	275	6	272	7.0e-88	317	COG0253	Diaminopimelate epimerase	272
650825810	332	37.81	10	329	1	317	2.0e-69	255	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650825811	339	46.63	1	339	4	329	4.0e-97	348	COG0240	Glycerol-3-phosphate dehydrogenase	329
650825812	174	45.33	9	158	3	152	1.0e-39	155	COG1952	Preprotein translocase subunit SecB	157
650825813	82	44	1	74	5	79	4.0e-14	69.6	COG0695	Glutaredoxin	80
650825814	136	33.33	34	135	5	109	8.0e-17	79.6	COG0607	Rhodanese-related sulfurtransferase	110
650825816	249	66.09	1	230	1	230	1.0e-101	363	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
650825817	475	29.98	10	475	16	420	5.0e-47	182	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
650825818	501	41.93	11	417	10	402	2.0e-90	326	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
650825819	253	24.39	25	215	5	204	3.0e-16	79.2	COG1011	FMN phosphatase YigB, HAD superfamily	229
650825820	286	50.37	17	284	1	264	1.0e-82	299	COG0548	Acetylglutamate kinase	265
650825821	164	22.69	27	145	10	127	1.0e-09	56.1	COG0526	Thiol-disulfide isomerase or thioredoxin	127
650825822	234	40.84	8	196	5	195	8.0e-31	127	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
650825823	191	54.91	3	175	7	176	1.0e-56	212	COG0279	Phosphoheptose isomerase	176
650825824	160	40.68	44	160	1	114	9.0e-27	113	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
650825825	314	44.13	27	307	3	275	4.0e-83	301	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
650825826	327	38.26	1	226	1	219	3.0e-40	159	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
650825827	290	47.92	2	282	1	281	3.0e-87	315	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
650825828	309	40.51	1	308	2	308	1.0e-75	276	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
650825829	151	31.79	3	151	1	151	2.0e-24	104	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
650825830	109	40.91	1	108	1	110	3.0e-22	96.5	COG1544	Ribosome-associated translation inhibitor RaiA	110
650825831	274	62.7	20	204	3	183	3.0e-76	278	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
650825832	212	27.75	16	205	2	171	2.0e-19	89.2	COG1934	Lipopolysaccharide export system protein LptA	173
650825833	207	18.71	11	181	10	176	4.0e-11	61.9	COG3117	Lipopolysaccharide export system protein LptC	188
650825834	199	47.56	22	185	1	164	3.0e-51	194	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
650825835	329	56.22	12	211	1	201	9.0e-61	227	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
650825836	183	45.09	8	180	7	179	1.0e-44	172	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
650825837	1312	21.74	899	1291	1	387	1.0e-45	179	COG0247	Fe-S oxidoreductase	388
650825838	241	57.92	1	240	2	240	3.0e-105	374	COG1126	ABC-type polar amino acid transport system, ATPase component	240
650825839	226	37	2	225	1	220	4.0e-41	161	COG0765	ABC-type amino acid transport system, permease component	222
650825840	237	30.9	1	233	1	222	2.0e-46	178	COG0765	ABC-type amino acid transport system, permease component	222
650825841	308	28.16	16	286	4	273	3.0e-33	135	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650825843	306	26.25	5	300	1	297	2.0e-31	129	COG0583	DNA-binding transcriptional regulator, LysR family	297
650825844	173	33.12	11	170	7	158	4.0e-19	88	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
650825845	502	51.3	1	341	4	347	2.0e-117	416	COG1171	Threonine dehydratase	347
650825847	392	23.08	131	389	78	322	7.0e-11	61.8	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
650825848	673	36.9	405	670	99	365	2.0e-46	181	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
650825849	821	25	415	809	5	388	1.0e-18	89.1	COG2814	Predicted arabinose efflux permease, MFS family	394
650825850	388	37.4	27	388	7	360	8.0e-72	264	COG0787	Alanine racemase	360
650825851	147	23.26	1	129	2	128	6.0e-12	63.5	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
650825852	590	26.02	20	450	4	442	2.0e-46	180	COG2233	Xanthine/uracil permease	451
650825853	259	30.62	49	257	6	214	1.0e-34	140	COG2091	Phosphopantetheinyl transferase	223
650825854	2335	32.38	241	896	1	642	8.0e-97	350	COG1020	Non-ribosomal peptide synthetase component F	642
650825855	1098	31.27	262	914	1	642	4.0e-93	336	COG1020	Non-ribosomal peptide synthetase component F	642
650825856	108	22.92	4	99	3	89	4.0e-05	40	COG1359	Quinol monooxygenase YgiN	100
650825859	265	27.43	30	263	8	234	4.0e-20	92.2	COG3208	Surfactin synthase thioesterase subunit	244
650825860	936	32.85	208	761	18	567	2.0e-109	390	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650825861	715	30.9	1	572	1	530	5.0e-80	292	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650825862	2990	41.34	48	1058	6	1024	0.0e+00	723	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
650825864	112	31.25	1	110	3	114	2.0e-10	57.7	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
650825865	328	43.57	3	320	1	310	6.0e-94	337	COG1984	Allophanate hydrolase subunit 2	314
650825866	245	50	16	244	1	223	3.0e-60	225	COG2049	Allophanate hydrolase subunit 1	223
650825867	143	56.83	5	143	1	138	7.0e-49	186	COG3565	Predicted dioxygenase of extradiol dioxygenase family	138
650825868	431	29.27	76	431	97	455	1.0e-45	177	COG5002	Signal transduction histidine kinase	459
650825869	233	48.68	5	228	3	228	8.0e-66	243	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650825870	262	53.81	26	258	1	235	4.0e-80	291	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
650825872	314	23.67	54	307	2	279	4.0e-17	82.3	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
650825873	208	25.79	18	205	15	203	2.0e-19	89.6	COG3165	Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain	204
650825874	518	45.17	1	512	4	511	0.0e+00	470	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
650825878	425	36.71	31	425	4	396	6.0e-108	384	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650825879	297	28.37	8	294	6	290	2.0e-32	132	COG0583	DNA-binding transcriptional regulator, LysR family	297
650825880	450	28.33	34	444	45	455	3.0e-38	152	COG1538	Outer membrane protein TolC	457
650825881	233	42.99	19	231	1	209	1.0e-50	193	COG2518	Protein-L-isoaspartate O-methyltransferase	209
650825882	273	52.04	1	269	2	263	4.0e-85	307	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
650825883	265	56.98	5	262	6	260	2.0e-97	348	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
650825884	319	25.7	9	308	1	319	1.0e-27	117	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
650825885	658	32.8	42	657	5	607	2.0e-105	376	COG4206	Outer membrane cobalamin receptor protein	608
650825887	1257	55.38	339	1226	1	842	0.0e+00	1099	COG1410	Methionine synthase I, cobalamin-binding domain	842
650825890	290	40.5	48	283	1	238	7.0e-43	167	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
650825891	283	49.3	1	280	1	282	5.0e-92	331	COG0414	Panthothenate synthetase	285
650825894	254	38.38	72	254	68	250	6.0e-14	71.6	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
650825895	215	36.95	1	203	2	197	1.0e-42	166	COG0237	Dephospho-CoA kinase	201
650825898	391	33.14	43	390	25	371	3.0e-32	132	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
650825899	1035	40.08	2	1016	1	1009	0.0e+00	920	COG0841	Multidrug efflux pump subunit AcrB	1009
650825900	1036	36.83	2	1018	1	1009	0.0e+00	877	COG0841	Multidrug efflux pump subunit AcrB	1009
650825901	521	36.61	76	510	24	457	3.0e-59	223	COG1538	Outer membrane protein TolC	457
650825902	323	27.37	130	319	4	187	3.0e-27	116	COG0352	Thiamine monophosphate synthase	211
650825903	288	57.29	1	287	1	281	2.0e-100	358	COG2607	Predicted ATPase, AAA+ superfamily	287
650825904	308	39.68	1	308	11	322	8.0e-74	270	COG0142	Geranylgeranyl pyrophosphate synthase	322
650825906	333	28.96	3	324	71	402	6.0e-28	118	COG3464	Transposase	402
650825908	222	32.27	1	219	10	228	4.0e-31	128	COG1802	DNA-binding transcriptional regulator, GntR family	230
650825909	396	26.7	15	390	28	371	1.0e-48	187	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
650825910	319	39.94	1	312	2	312	2.0e-71	262	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
650825911	202	48.6	1	179	1	179	6.0e-51	193	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
650825913	360	48.9	1	356	1	362	5.0e-118	417	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
650825914	165	61.59	11	161	11	160	6.0e-55	206	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
650825915	198	25.68	8	189	11	193	5.0e-09	54.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650825916	185	22.81	67	180	24	129	2.0e-05	42.3	COG1765	Uncharacterized OsmC-related protein	137
650825917	349	41.19	1	349	1	316	8.0e-86	310	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650825918	107	18.81	1	101	2	98	2.0e-04	37.3	COG3668	Plasmid stabilization system protein ParE	98
650825920	326	35.37	1	324	1	324	6.0e-56	211	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
650825921	546	37.91	7	546	1	539	1.0e-126	446	COG2303	Choline dehydrogenase or related flavoprotein	542
650825922	344	36.56	8	337	19	349	1.0e-72	267	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
650825924	446	44.32	4	445	6	444	5.0e-89	321	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
650825925	731	45.09	399	719	1	322	8.0e-97	348	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
650825926	240	37.94	3	236	1	249	9.0e-36	143	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650825927	231	29.96	1	227	1	222	9.0e-29	120	COG1802	DNA-binding transcriptional regulator, GntR family	230
650825928	390	41.38	1	390	1	403	1.0e-91	330	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
650825929	158	50	1	157	1	157	7.0e-42	163	COG2193	Bacterioferritin (cytochrome b1)	157
650825931	283	27.53	26	267	1	244	3.0e-38	152	COG1414	DNA-binding transcriptional regulator, IclR family	246
650825932	707	34.68	18	633	3	597	7.0e-95	341	COG1042	Acyl-CoA synthetase (NDP forming)	598
650825933	380	43.08	1	380	1	390	6.0e-81	294	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650825934	383	27.72	2	382	1	390	3.0e-47	182	COG0183	Acetyl-CoA acetyltransferase	392
650825935	132	37.61	15	122	18	125	2.0e-21	95	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
650825938	326	36.16	6	323	1	317	7.0e-62	231	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650825939	294	28.62	3	294	4	294	5.0e-35	141	COG0583	DNA-binding transcriptional regulator, LysR family	297
650825940	388	26.52	1	385	1	368	8.0e-46	177	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
650825941	311	42.56	26	311	26	312	6.0e-57	214	COG0657	Acetyl esterase/lipase	312
650825942	327	33.44	12	327	5	319	4.0e-56	212	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650825943	327	36.99	6	324	1	317	1.0e-68	253	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650825944	294	36.43	1	288	85	372	2.0e-57	216	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
650825945	351	34.56	7	324	2	324	5.0e-72	265	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
650825946	298	35.66	8	292	3	286	2.0e-56	212	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
650825947	486	50.11	15	479	5	466	0.0e+00	540	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650825948	262	38.79	5	232	4	233	3.0e-36	145	COG2186	DNA-binding transcriptional regulator, FadR family	241
650825949	369	32.24	36	362	33	365	2.0e-46	179	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
650825950	372	41.6	1	372	20	393	1.0e-59	224	COG2814	Predicted arabinose efflux permease, MFS family	394
650825952	398	21.27	2	398	5	411	1.0e-12	67.6	COG2223	Nitrate/nitrite transporter NarK	417
650825953	321	40.99	1	320	1	319	7.0e-64	237	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650825954	264	40.38	1	259	3	254	5.0e-52	197	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650825956	384	32.66	10	384	4	389	7.0e-47	181	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650825957	340	24.23	1	325	8	392	6.0e-14	72.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650825958	412	49.25	13	411	1	396	2.0e-116	413	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650825959	261	37.08	1	239	1	234	3.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
650825960	284	38.03	1	283	5	261	5.0e-56	211	COG3228	Mlc titration factor MtfA, regulates ptsG expression	266
650825961	252	33.87	3	248	4	246	6.0e-40	157	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
650825962	235	37.11	23	216	14	201	3.0e-31	128	COG3647	Uncharacterized membrane protein YjdF	205
650825963	399	19.57	22	391	23	390	8.0e-09	55.2	COG2814	Predicted arabinose efflux permease, MFS family	394
650825964	566	21.29	13	476	4	481	3.0e-31	130	COG0591	Na+/proline symporter	493
650825966	950	45.71	8	950	3	910	0.0e+00	937	COG2352	Phosphoenolpyruvate carboxylase	910
650825967	220	40.64	27	213	3	185	3.0e-30	125	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
650825970	428	30.37	11	427	4	382	6.0e-50	192	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
650825971	170	38.82	15	166	2	152	7.0e-34	136	COG1522	DNA-binding transcriptional regulator, Lrp family	154
650825972	393	52.85	10	377	2	368	1.0e-125	443	COG0263	Glutamate 5-kinase	369
650825973	368	57.45	1	366	1	361	0.0e+00	479	COG0536	GTPase involved in cell partioning and DNA repair	369
650825974	348	21.88	52	348	66	381	4.0e-18	86.2	COG1680	CubicO group peptidase, beta-lactamase class C family	390
650825976	86	74.42	1	86	1	85	3.0e-29	119	COG0211	Ribosomal protein L27	87
650825977	103	53.4	1	103	1	103	1.0e-32	131	COG0261	Ribosomal protein L21	103
650825978	408	44.36	2	408	1	404	0.0e+00	466	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
650825979	187	28.81	55	172	4	120	5.0e-13	67.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
650825980	779	40	407	760	4	352	9.0e-101	361	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
650825981	262	43.41	7	257	3	249	7.0e-46	177	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650825982	283	35.16	26	280	8	257	2.0e-46	179	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650825983	395	44.85	44	393	42	393	4.0e-66	245	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650825984	552	30.48	35	549	5	522	5.0e-109	388	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
650825985	135	28.8	10	133	9	129	2.0e-17	81.9	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
650825986	425	61.97	1	425	4	429	0.0e+00	604	COG0001	Glutamate-1-semialdehyde aminotransferase	432
650825987	216	38.32	5	216	2	207	3.0e-38	151	COG0352	Thiamine monophosphate synthase	211
650825988	264	27.07	4	263	1	260	4.0e-24	105	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
650825989	197	49.48	9	197	6	194	6.0e-54	203	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
650825990	137	42.11	8	131	3	135	2.0e-31	128	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
650825991	249	23.83	4	243	1	255	2.0e-22	99	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
650825993	392	27.61	1	368	1	358	1.0e-33	137	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
650825995	272	40.88	2	270	12	281	2.0e-68	252	COG0169	Shikimate 5-dehydrogenase	283
650825996	292	19.84	20	265	9	227	9.0e-04	37.8	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
650825997	628	20.1	13	565	1	571	6.0e-39	155	COG0557	Exoribonuclease R	706
650825998	201	33.68	1	193	1	186	3.0e-40	158	COG3150	Predicted esterase YcpF, UPF0227 family	191
650825999	452	39.05	2	452	9	457	2.0e-127	449	COG0773	UDP-N-acetylmuramate-alanine ligase	459
650826000	169	28.23	29	150	4	125	8.0e-12	63.4	COG0526	Thiol-disulfide isomerase or thioredoxin	127
650826001	144	60	4	143	2	140	1.0e-54	205	COG0757	3-dehydroquinate dehydratase	146
650826002	145	47.59	6	144	1	138	3.0e-25	107	COG0511	Biotin carboxyl carrier protein	140
650826003	448	63.92	1	447	1	448	0.0e+00	613	COG0439	Biotin carboxylase	449
650826004	306	41.75	3	305	6	300	7.0e-77	281	COG2264	Ribosomal protein L11 methylase PrmA	300
650826006	318	27.04	4	305	1	309	3.0e-36	146	COG0524	Sugar or nucleoside kinase, ribokinase family	311
650826007	166	45.71	28	165	15	154	1.0e-25	109	COG3133	Outer membrane lipoprotein SlyB	154
650826008	187	34.04	95	185	1	94	3.0e-04	38.2	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
650826011	387	38.46	49	385	8	339	5.0e-100	358	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
650826012	973	36.1	185	919	1	647	0.0e+00	579	COG0209	Ribonucleotide reductase alpha subunit	696
650826013	1176	29.2	21	686	2	633	0.0e+00	485	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
650826014	150	44	1	150	6	154	3.0e-34	137	COG1522	DNA-binding transcriptional regulator, Lrp family	154
650826016	469	40.13	1	466	2	466	0.0e+00	481	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
650826018	224	32.29	3	224	1	207	2.0e-39	156	COG0400	Predicted esterase	207
650826019	197	46.41	18	197	13	185	9.0e-37	146	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
650826020	455	37.67	20	454	3	453	1.0e-81	296	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
650826021	366	51.94	1	356	1	360	1.0e-128	453	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
650826022	176	64.34	35	176	1	143	2.0e-54	205	COG0102	Ribosomal protein L13	148
650826023	130	60	1	130	1	130	4.0e-47	179	COG0103	Ribosomal protein S9	130
650826024	378	50.86	33	378	3	349	1.0e-118	420	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
650826026	122	56.48	13	120	1	108	2.0e-39	153	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
650826027	370	50	1	370	2	370	2.0e-95	342	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
650826029	409	39.45	14	407	5	400	7.0e-114	404	COG0162	Tyrosyl-tRNA synthetase	401
650826030	212	32.35	1	204	23	174	1.0e-31	129	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
650826031	414	66.59	6	413	5	412	0.0e+00	639	COG0112	Glycine/serine hydroxymethyltransferase	413
650826032	153	58.78	1	148	1	148	2.0e-51	195	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
650826033	374	59.72	3	146	6	146	7.0e-48	184	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
650826034	210	46.95	1	210	1	201	3.0e-58	218	COG0307	Riboflavin synthase alpha chain	204
650826035	301	27.09	1	296	1	289	7.0e-24	104	COG0583	DNA-binding transcriptional regulator, LysR family	297
650826036	558	40.32	1	556	3	535	0.0e+00	481	COG2303	Choline dehydrogenase or related flavoprotein	542
650826037	235	27.27	1	219	9	221	4.0e-27	115	COG1802	DNA-binding transcriptional regulator, GntR family	230
650826038	289	46.75	61	287	44	266	7.0e-68	251	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
650826039	342	37.61	10	335	6	332	8.0e-78	284	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650826040	462	38.88	14	462	1	458	1.0e-89	323	COG0277	FAD/FMN-containing dehydrogenase	459
650826041	167	35.8	1	162	5	166	6.0e-22	97.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
650826042	426	53.17	47	424	1	378	1.0e-97	350	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650826044	333	28.96	3	324	71	402	6.0e-28	118	COG3464	Transposase	402
650826048	93	35.71	5	88	26	102	7.0e-12	62.3	COG2944	DNA-binding transcriptional regulator YiaG, XRE-type HTH domain	104
650826049	580	42.41	1	565	1	573	0.0e+00	617	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
650826050	155	30.82	14	154	1	138	3.0e-21	94.7	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
650826051	118	48.74	1	114	17	135	4.0e-30	123	COG3474	Cytochrome c2	135
650826052	191	22.82	45	177	19	163	1.0e-05	43.5	COG1633	Rubrerythrin	176
650826053	242	34.55	16	206	1	182	6.0e-26	111	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650826054	313	34.3	2	310	10	317	5.0e-59	221	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650826056	267	36.11	17	266	7	255	3.0e-41	162	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
650826057	254	29.84	5	250	1	246	4.0e-30	124	COG1414	DNA-binding transcriptional regulator, IclR family	246
650826059	357	29.75	1	149	1	154	3.0e-12	66.6	COG1988	Membrane-bound metal-dependent hydrolase YbcI, DUF457 family	190
650826061	308	50	1	305	2	303	2.0e-115	408	COG1054	Predicted sulfurtransferase	308
650826062	202	25.41	2	175	14	194	4.0e-13	67.9	COG0625	Glutathione S-transferase	211
650826063	260	64.31	1	255	1	253	1.0e-105	376	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
650826065	234	34.47	1	176	44	244	5.0e-18	84.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650826067	154	60.14	3	147	1	148	5.0e-51	193	COG0328	Ribonuclease HI	154
650826068	371	35.49	30	362	18	372	1.0e-28	120	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
650826069	1029	41.82	3	1004	2	1007	0.0e+00	958	COG0841	Multidrug efflux pump subunit AcrB	1009
650826070	236	32.76	1	230	13	240	2.0e-41	162	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
650826074	223	28	1	220	21	230	6.0e-26	110	COG1018	Ferredoxin-NADP reductase	266
650826075	362	38.26	1	342	3	335	1.0e-90	326	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
650826076	101	31.96	1	95	2	98	5.0e-08	49.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650826078	423	32.56	1	423	38	457	2.0e-85	309	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
650826080	144	25	1	134	11	158	1.0e-10	59.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
650826081	167	32.9	9	157	6	159	3.0e-26	111	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
650826082	464	21.84	24	423	4	336	1.0e-43	171	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
650826083	421	23.84	31	389	3	363	5.0e-35	142	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650826084	296	27.05	1	288	1	290	6.0e-30	125	COG0583	DNA-binding transcriptional regulator, LysR family	297
650826086	404	24.93	21	377	1	364	5.0e-44	172	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650826087	310	46.05	5	305	3	298	8.0e-85	307	COG3246	Uncharacterized conserved protein, DUF849 family	298
650826089	520	25.41	6	485	6	458	5.0e-51	196	COG3119	Arylsulfatase A or related enzyme	475
650826090	327	33.23	3	324	2	318	2.0e-51	196	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650826091	178	30.17	31	146	1	116	7.0e-12	63.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
650826092	304	33.11	12	300	5	295	5.0e-46	178	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
650826093	574	34.24	19	566	2	545	0.0e+00	480	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
650826094	329	41.74	5	325	1	317	9.0e-66	244	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
650826095	320	28.62	1	296	1	294	1.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
650826096	396	36.58	18	396	3	358	1.0e-78	287	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
650826097	520	43.13	106	520	1	381	4.0e-117	415	COG2721	Altronate dehydratase	381
650826099	310	35.53	1	305	5	290	4.0e-53	201	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
650826100	701	22.85	1	701	3	768	5.0e-33	136	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
650826102	333	20.42	49	331	42	290	7.0e-14	71.6	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
650826103	178	23.28	1	116	17	127	2.0e-04	38.9	COG4101	Uncharacterized protein, RmlC-like cupin domain	142
650826104	142	41.6	16	139	15	129	1.0e-21	95.7	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
650826105	487	43.24	8	486	2	468	0.0e+00	470	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650826106	479	70.65	2	478	1	463	0.0e+00	626	COG1282	NAD/NADP transhydrogenase beta subunit	463
650826108	372	54.92	2	366	1	355	7.0e-111	393	COG3288	NAD/NADP transhydrogenase alpha subunit	356
650826110	425	67.14	1	423	6	426	0.0e+00	651	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
650826114	168	57.59	1	158	2	159	3.0e-62	231	COG0669	Phosphopantetheine adenylyltransferase	159
650826115	199	38.62	6	185	2	187	4.0e-41	161	COG0742	16S rRNA G966 N2-methylase RsmD	187
650826116	378	48.36	56	377	10	340	5.0e-94	338	COG0552	Signal recognition particle GTPase	340
650826118	269	44.05	20	269	32	282	1.0e-45	176	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
650826119	268	35.12	1	237	37	278	5.0e-41	161	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
650826120	256	48.21	3	253	2	248	2.0e-74	272	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
650826121	330	25.83	49	313	24	293	2.0e-35	143	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
650826122	275	31.2	18	267	1	246	3.0e-43	168	COG1414	DNA-binding transcriptional regulator, IclR family	246
650826123	399	57.84	25	228	1	203	6.0e-79	288	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
650826124	174	48	5	150	3	152	2.0e-40	158	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
650826125	166	41.96	21	160	8	150	6.0e-32	130	COG0781	Transcription termination factor NusB	151
650826126	322	42.81	6	321	4	317	3.0e-75	275	COG0611	Thiamine monophosphate kinase	317
650826127	174	34.42	16	167	7	159	5.0e-22	97.7	COG1267	Phosphatidylglycerophosphatase A	160
650826128	168	51.3	13	166	13	161	3.0e-43	167	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
650826129	271	29.25	18	265	14	240	7.0e-30	124	COG0284	Orotidine-5'-phosphate decarboxylase	240
650826130	128	45.08	7	128	1	122	3.0e-26	110	COG0818	Diacylglycerol kinase	123
650826131	548	48.74	1	538	1	524	0.0e+00	490	COG0459	Chaperonin GroEL (HSP60 family)	524
650826132	95	59.57	1	94	1	94	1.0e-29	121	COG0234	Co-chaperonin GroES (HSP10)	96
650826133	391	22.98	14	329	5	300	2.0e-27	117	COG0644	Dehydrogenase (flavoprotein)	396
650826137	270	42.91	1	266	1	265	1.0e-62	233	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
650826138	361	37.71	11	359	1	349	9.0e-69	254	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
650826139	226	49.78	1	226	3	229	2.0e-76	278	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
650826140	739	38.4	29	738	28	750	0.0e+00	606	COG4774	Outer membrane receptor for monomeric catechols	750
650826142	237	41.52	15	233	3	225	3.0e-47	182	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650826143	430	22.71	121	426	26	327	1.0e-26	114	COG0642	Signal transduction histidine kinase	336
650826146	214	36.11	36	207	2	177	3.0e-29	122	COG0431	NAD(P)H-dependent FMN reductase	184
650826147	293	26.32	9	292	6	288	3.0e-03	36.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
650826148	150	41.1	2	147	4	149	4.0e-26	110	COG3556	Uncharacterized membrane protein	150
650826149	384	49.35	1	382	12	393	6.0e-88	317	COG2807	Cyanate permease	395
650826150	187	50.53	1	184	2	188	4.0e-67	247	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
650826151	532	73.7	1	518	1	520	0.0e+00	851	COG3634	Alkyl hydroperoxide reductase subunit AhpF	520
650826153	712	30.08	1	629	1	640	1.0e-83	304	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
650826155	507	48.51	1	495	1	501	0.0e+00	595	COG3845	ABC-type uncharacterized transport system, ATPase component	501
650826156	352	45.43	3	351	2	349	6.0e-78	284	COG4603	ABC-type uncharacterized transport system, permease component	356
650826157	305	46.71	1	303	4	302	1.0e-71	263	COG1079	ABC-type uncharacterized transport system, permease component	304
650826158	363	38.3	1	333	4	342	1.0e-76	280	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
650826159	331	37.73	1	319	1	316	1.0e-77	283	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650826160	178	34.4	54	176	14	138	1.0e-17	83.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
650826161	172	34.96	51	172	26	148	6.0e-19	87.3	COG2847	Copper(I)-binding protein	151
650826162	267	24.91	5	265	3	282	2.0e-18	86.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650826163	227	25.13	27	225	63	259	2.0e-21	96.2	COG1729	Periplasmic TolA-binding protein (function unknown)	262
650826164	165	27.88	1	165	25	189	1.0e-23	102	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
650826165	436	40.71	22	435	2	425	8.0e-84	304	COG0823	Periplasmic component of the Tol biopolymer transport system	425
650826167	148	37.76	4	142	2	137	5.0e-25	107	COG0848	Biopolymer transport protein ExbD	137
650826168	224	42.06	12	224	1	214	1.0e-45	176	COG0811	Biopolymer transport protein ExbB/TolQ	216
650826169	141	42.42	10	141	6	136	7.0e-33	133	COG0824	Acyl-CoA thioesterase FadM	137
650826170	577	45.23	1	572	1	500	0.0e+00	552	COG0442	Prolyl-tRNA synthetase	500
650826172	229	40.97	1	219	1	226	2.0e-46	178	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650826173	472	25.96	136	471	16	334	7.0e-33	135	COG0642	Signal transduction histidine kinase	336
650826174	301	46.5	15	300	1	286	6.0e-86	311	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
650826175	501	55.29	1	500	1	501	0.0e+00	587	COG3333	TctA family transporter	504
650826179	241	31.8	5	234	3	233	2.0e-23	102	COG3471	Predicted secreted (periplasmic) protein	235
650826180	261	48.73	1	259	5	277	1.0e-67	249	COG0682	Prolipoprotein diacylglyceryltransferase	287
650826181	118	40.62	10	105	9	104	4.0e-15	73.6	COG4654	Cytochrome c551/c552	110
650826182	175	46.78	1	167	5	174	3.0e-57	214	COG0225	Peptide methionine sulfoxide reductase MsrA	174
650826184	370	59.02	4	367	10	360	0.0e+00	471	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
650826185	144	43.75	1	144	15	154	2.0e-30	125	COG1522	DNA-binding transcriptional regulator, Lrp family	154
650826192	121	31.07	14	116	19	116	3.0e-13	67.2	COG3671	Uncharacterized membrane protein	125
650826209	139	22.89	1	139	3	167	9.0e-13	66.3	COG0629	Single-stranded DNA-binding protein	167
650826220	79	30.51	1	58	8	64	2.0e-03	34.1	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
650826222	327	24.12	81	314	34	281	2.0e-09	57.1	COG4974	Site-specific recombinase XerD	300
650826226	190	45.45	36	176	8	149	7.0e-33	133	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
650826246	108	33.64	1	107	3	109	9.0e-22	95	COG5614	Bacteriophage head-tail adaptor	109
650826249	404	25.18	20	404	18	422	1.0e-33	137	COG4653	Predicted phage phi-C31 gp36 major capsid-like protein	422
650826250	240	31.76	27	191	26	192	6.0e-27	114	COG0740	ATP-dependent protease ClpP, protease subunit	200
650826251	431	27.99	49	407	40	387	3.0e-43	169	COG4695	Phage portal protein BeeE	398
650826252	506	25.73	8	506	37	546	2.0e-61	230	COG4626	Phage terminase-like protein, large subunit, contains N-terminal HTH domain	546
650826263	244	25.54	24	240	24	245	5.0e-25	108	COG1484	DNA replication protein DnaC	254
