gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
644987595	461	52.88	6	457	1	408	0.0e+00	474	COG0593	Chromosomal replication initiation ATPase DnaA	408
644987596	367	38.86	1	367	1	364	2.0e-85	309	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
644987597	369	32.43	1	359	1	362	5.0e-80	291	COG1195	Recombinational DNA repair ATPase RecF	363
644987598	808	65.36	2	561	1	558	0.0e+00	900	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
644987599	311	27.65	16	279	20	264	4.0e-61	228	COG2326	Polyphosphate kinase 2, PPK2 family	270
644987600	67	34.33	1	67	3	69	9.0e-08	48.4	COG3360	Flavin-binding protein dodecin	71
644987601	487	27.52	17	482	5	520	1.0e-33	138	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
644987602	659	40.57	156	643	4	494	0.0e+00	470	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
644987603	80	43.75	1	80	10	89	7.0e-13	65.4	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
644987604	121	36.29	2	120	4	127	2.0e-14	71.1	COG3094	Uncharacterized membrane protein SirB2	129
644987605	217	34.52	19	214	7	201	1.0e-40	160	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
644987607	718	40.51	314	623	2	305	4.0e-86	312	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
644987608	389	41.83	2	388	1	392	3.0e-91	328	COG0183	Acetyl-CoA acetyltransferase	392
644987611	674	43.12	5	655	2	655	0.0e+00	572	COG0210	Superfamily I DNA or RNA helicase	655
644987612	287	26.85	1	208	11	216	2.0e-24	106	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644987617	127	36.36	31	126	20	108	3.0e-13	67.6	COG0607	Rhodanese-related sulfurtransferase	110
644987618	111	39.6	10	109	2	101	3.0e-08	50.6	COG0640	DNA-binding transcriptional regulator, ArsR family	110
644987619	487	26.21	3	452	8	405	2.0e-64	240	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
644987622	163	32.53	1	161	17	182	3.0e-25	107	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644987641	206	23.66	7	182	9	178	1.0e-16	80.1	COG4725	N6-adenosine-specific RNA methylase IME4	198
644987654	111	55	1	60	1	59	1.0e-12	65.3	COG3422	Uncharacterized conserved protein YegP, UPF0339 family	59
644987655	143	28.19	2	127	5	150	4.0e-11	60.8	COG4502	5'(3')-deoxyribonucleotidase	180
644987656	86	25.97	5	79	1	77	7.0e-08	48.8	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
644987659	661	19.24	1	488	1	458	5.0e-29	123	COG3593	Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains	581
644987660	610	21.54	24	584	9	615	2.0e-48	187	COG0210	Superfamily I DNA or RNA helicase	655
644987670	495	32.74	157	493	2	329	8.0e-36	145	COG0642	Signal transduction histidine kinase	336
644987671	220	46.67	5	220	3	226	1.0e-53	202	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644987673	500	32.22	315	491	1	173	2.0e-27	117	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644987675	249	43.58	70	247	9	181	3.0e-39	155	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644987678	158	54.46	8	108	11	111	4.0e-27	114	COG4628	Uncharacterized conserved protein, DUF2132 family	136
644987679	129	35.71	1	112	1	112	9.0e-21	92.6	COG1725	DNA-binding transcriptional regulator YhcF, GntR family	125
644987680	335	32.46	24	283	4	271	2.0e-50	193	COG1131	ABC-type multidrug transport system, ATPase component	293
644987682	694	21.74	57	666	4	619	4.0e-40	159	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
644987683	434	43.45	1	430	29	460	8.0e-113	400	COG0513	Superfamily II DNA and RNA helicase	513
644987684	150	34.86	1	103	1	109	3.0e-14	71.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
644987685	190	22.15	14	170	5	152	9.0e-06	43.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
644987687	70	60.87	1	69	1	69	4.0e-19	86.1	COG3655	DNA-binding transcriptional regulator, XRE family	73
644987688	436	21.79	25	336	35	390	3.0e-21	97	COG1680	CubicO group peptidase, beta-lactamase class C family	390
644987689	358	18.9	26	316	18	358	6.0e-25	108	COG1680	CubicO group peptidase, beta-lactamase class C family	390
644987690	492	23.08	64	371	50	365	4.0e-32	132	COG1680	CubicO group peptidase, beta-lactamase class C family	390
644987691	352	25.36	31	348	36	382	2.0e-28	120	COG1680	CubicO group peptidase, beta-lactamase class C family	390
644987692	717	66.94	2	717	14	729	0.0e+00	1168	COG0376	Catalase (peroxidase I)	730
644987695	181	31.69	3	179	1	181	2.0e-26	112	COG3038	Cytochrome b561	181
644987699	198	51.98	17	193	29	199	1.0e-61	229	COG3738	Uncharacterized protein YijF, DUF1287 family	200
644987700	136	36.09	4	127	21	151	7.0e-20	89.6	COG0782	Transcription elongation factor, GreA/GreB family	151
644987701	94	60.92	6	92	5	91	2.0e-21	94	COG3461	Uncharacterized protein	103
644987702	393	40.33	214	393	1	180	4.0e-39	156	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644987704	263	29.9	1	263	2	291	3.0e-48	185	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
644987706	222	23.62	1	199	1	184	1.0e-18	86.6	COG0431	NAD(P)H-dependent FMN reductase	184
644987707	673	37.02	453	633	3	177	3.0e-35	143	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644987708	908	41.18	6	898	19	917	0.0e+00	769	COG0474	Magnesium-transporting ATPase (P-type)	917
644987709	452	48.24	272	440	3	171	3.0e-43	169	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644987710	171	38.41	16	166	12	158	7.0e-21	93.8	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
644987711	179	45.36	1	178	3	185	4.0e-29	121	COG1971	Putative Mn2+ efflux pump MntP	190
644987712	398	30.26	43	377	2	346	2.0e-55	209	COG1253	Hemolysin or related protein, contains CBS domains	429
644987714	218	28.25	54	215	67	243	9.0e-25	106	COG3751	Proline 4-hydroxylase (includes Rps23 Pro-64 3,4-dihydroxylase Tpa1), contains SM-20 domain	252
644987715	350	42.81	4	309	2	300	8.0e-85	307	COG0031	Cysteine synthase	300
644987716	128	41.41	1	125	1	124	7.0e-25	106	COG3603	Uncharacterized protein	128
644987717	154	37.88	43	154	15	143	6.0e-20	90.4	COG3296	Uncharacterized conserved protein, Tic20 family	143
644987718	615	65.58	127	586	2	431	0.0e+00	755	COG0422	Thiamine biosynthesis protein ThiC	432
644987719	351	26.84	1	327	5	356	3.0e-32	132	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644987720	65	42.42	1	65	3	68	1.0e-10	58.3	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
644987721	257	53.12	1	253	7	261	7.0e-102	363	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
644987722	493	40	7	259	4	256	6.0e-59	222	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
644987723	117	28.85	13	114	4	101	2.0e-11	61.5	COG0607	Rhodanese-related sulfurtransferase	110
644987724	184	26	36	178	7	153	2.0e-15	75.3	COG3402	Uncharacterized membrane protein YdbS, contains bPH2 (bacterial pleckstrin homology) domain	161
644987725	496	22.36	9	487	6	487	8.0e-49	188	COG3428	Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain	494
644987726	398	48.33	4	391	2	388	4.0e-127	448	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
644987727	341	33.99	1	340	1	350	4.0e-80	291	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
644987728	153	46	1	146	2	150	2.0e-39	155	COG2153	Predicted N-acyltransferase, GNAT family	155
644987729	199	25.12	1	198	8	214	6.0e-09	54.3	COG0705	Membrane associated serine protease, rhomboid family	228
644987730	102	31.68	1	98	3	103	8.0e-18	81.9	COG0607	Rhodanese-related sulfurtransferase	110
644987732	536	50.1	1	515	1	515	0.0e+00	596	COG3634	Alkyl hydroperoxide reductase subunit AhpF	520
644987733	187	50.53	1	184	2	188	4.0e-64	237	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
644987734	300	27.61	2	296	1	292	2.0e-34	139	COG0583	DNA-binding transcriptional regulator, LysR family	297
644987735	186	27.51	1	185	1	171	8.0e-18	83.5	COG3161	4-hydroxybenzoate synthetase (chorismate-pyruvate lyase)	174
644987736	286	40.78	1	281	5	286	1.0e-49	190	COG0382	4-hydroxybenzoate polyprenyltransferase	289
644987737	850	39.24	5	782	2	770	0.0e+00	650	COG2937	Glycerol-3-phosphate O-acyltransferase	810
644987738	408	32.76	9	408	1	394	1.0e-79	290	COG0019	Diaminopimelate decarboxylase	394
644987739	523	32.65	1	519	9	528	5.0e-105	375	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644987743	225	59.01	1	222	1	220	4.0e-87	314	COG0036	Pentose-5-phosphate-3-epimerase	220
644987744	286	56.54	91	281	2	188	2.0e-80	292	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
644987745	211	32.66	10	207	13	210	4.0e-36	144	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
644987746	132	35.04	1	131	2	137	2.0e-27	114	COG1765	Uncharacterized OsmC-related protein	137
644987747	133	20	8	126	1	138	5.0e-07	47.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644987748	874	24.04	54	874	69	927	7.0e-68	252	COG5373	Uncharacterized membrane protein	931
644987749	743	68.54	17	743	12	730	0.0e+00	1117	COG0376	Catalase (peroxidase I)	730
644987750	146	36.73	48	143	33	129	9.0e-24	102	COG3474	Cytochrome c2	135
644987752	264	33.83	9	262	5	273	2.0e-57	215	COG0169	Shikimate 5-dehydrogenase	283
644987753	450	27.21	4	448	6	462	7.0e-34	138	COG1757	Na+/H+ antiporter NhaC	485
644987757	408	35.26	1	397	1	397	1.0e-68	253	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
644987758	426	30.81	68	425	20	378	3.0e-38	153	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
644987759	250	23.6	6	249	3	246	8.0e-24	103	COG1587	Uroporphyrinogen-III synthase	248
644987760	311	56.77	5	305	3	305	1.0e-111	396	COG0181	Porphobilinogen deaminase	307
644987761	234	41.49	1	229	1	241	3.0e-46	178	COG3279	DNA-binding response regulator, LytR/AlgR family	244
644987762	346	25.3	19	343	122	453	4.0e-30	125	COG2972	Sensor histidine kinase YesM	456
644987763	552	44.05	296	547	2	252	4.0e-72	266	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644987764	222	29.52	1	222	1	207	2.0e-36	145	COG0400	Predicted esterase	207
644987765	105	48.57	1	103	1	105	2.0e-26	110	COG1965	Iron-binding protein CyaY, frataxin homolog	106
644987767	276	48.91	3	276	1	272	3.0e-90	324	COG0253	Diaminopimelate epimerase	272
644987768	225	34.76	15	222	7	215	3.0e-30	125	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
644987769	299	53.54	1	297	6	299	9.0e-97	346	COG4973	Site-specific recombinase XerC	299
644987770	221	22.33	10	219	1	210	2.0e-21	96.1	COG1011	FMN phosphatase YigB, HAD superfamily	229
644987772	317	37.96	1	317	1	313	9.0e-74	270	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
644987773	254	28.19	32	252	34	260	2.0e-24	106	COG3971	2-keto-4-pentenoate hydratase	264
644987774	726	45.12	10	651	3	649	0.0e+00	604	COG0210	Superfamily I DNA or RNA helicase	655
644987781	371	42.7	5	366	1	357	5.0e-102	364	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
644987782	272	41.35	1	264	3	262	2.0e-72	265	COG0796	Glutamate racemase	269
644987783	462	49.34	8	462	6	447	8.0e-112	397	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
644987784	196	38.12	4	184	2	181	2.0e-36	145	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
644987785	559	25.09	94	361	84	371	3.0e-34	140	COG1680	CubicO group peptidase, beta-lactamase class C family	390
644987786	114	27.12	1	107	1	118	5.0e-11	59.5	COG3070	Transcriptional regulator of competence genes, TfoX/Sxy family	121
644987789	202	35.96	1	202	4	205	8.0e-39	153	COG4339	Predicted metal-dependent phosphohydrolase, HD superfamily	208
644987792	573	18.09	1	568	4	591	4.0e-22	99.7	COG5293	Uncharacterized protein YydD, contains DUF2326 domain	591
644987794	348	29.39	11	273	1	277	2.0e-27	117	COG0515	Serine/threonine protein kinase	384
644987798	476	37.68	7	471	4	433	2.0e-97	349	COG1030	Membrane-bound serine protease (ClpP class)	436
644987800	91	61.36	1	88	1	88	2.0e-31	127	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
644987801	355	46.8	1	351	2	340	3.0e-104	371	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
644987802	609	18.67	112	609	36	458	4.0e-23	103	COG0471	Di- and tricarboxylate transporter	461
644987803	233	49.55	13	231	2	223	2.0e-68	252	COG0220	tRNA G46 methylase TrmB	227
644987805	410	42.49	8	391	34	414	2.0e-109	389	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
644987806	210	49.51	1	205	1	194	3.0e-61	228	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
644987809	285	47.94	12	277	3	265	7.0e-69	254	COG0345	Pyrroline-5-carboxylate reductase	266
644987810	227	51.54	2	227	1	227	5.0e-71	260	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
644987811	344	65.8	1	344	3	347	0.0e+00	534	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
644987812	379	64.15	1	370	5	375	0.0e+00	555	COG5008	Tfp pilus assembly protein, ATPase PilU	375
644987813	753	40.08	488	739	3	251	5.0e-65	242	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644987814	145	40.15	8	143	2	138	5.0e-36	143	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
644987815	187	50.26	1	187	7	194	3.0e-60	224	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
644987816	303	22.96	105	296	54	244	4.0e-11	62.5	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
644987817	316	38.2	5	314	3	315	2.0e-67	249	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
644987820	182	26.95	41	181	21	161	4.0e-22	98.1	COG0835	Chemotaxis signal transduction protein	165
644987821	781	37.1	339	682	67	408	7.0e-42	166	COG0840	Methyl-accepting chemotaxis protein	408
644987822	291	33.94	17	289	4	265	4.0e-54	205	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
644987823	2213	35.58	1551	2072	183	711	5.0e-104	373	COG0643	Chemotaxis protein histidine kinase CheA	716
644987826	242	40.89	1	241	1	246	5.0e-66	244	COG1385	16S rRNA U1498 N3-methylase RsmE	246
644987827	449	44.91	2	449	1	447	0.0e+00	542	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
644987829	465	55	1	457	2	420	0.0e+00	625	COG0499	S-adenosylhomocysteine hydrolase	420
644987830	386	70.69	1	386	1	388	0.0e+00	688	COG0192	S-adenosylmethionine synthetase	388
644987834	212	44.33	8	210	2	202	6.0e-57	214	COG2941	Demethoxyubiquinone hydroxylase, CLK1/Coq7/Cat5 family	204
644987836	197	23.67	1	195	1	203	3.0e-17	81.8	COG0625	Glutathione S-transferase	211
644987837	110	35.14	1	110	1	109	7.0e-14	68.9	COG3784	Uncharacterized conserved protein YdbL, DUF1318 family	109
644987840	427	60	1	426	1	428	0.0e+00	613	COG0151	Phosphoribosylamine-glycine ligase	428
644987841	521	62.12	6	521	1	515	0.0e+00	786	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
644987842	101	51.32	26	101	23	98	4.0e-20	89.7	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
644987843	329	48.92	4	323	2	321	2.0e-99	355	COG0042	tRNA-dihydrouridine synthase	323
644987845	295	44.48	1	294	2	300	4.0e-83	301	COG2264	Ribosomal protein L11 methylase PrmA	300
644987847	449	66.37	1	444	1	445	0.0e+00	626	COG0439	Biotin carboxylase	449
644987848	151	43.84	6	151	1	139	6.0e-27	113	COG0511	Biotin carboxyl carrier protein	140
644987849	146	51.39	3	146	2	144	9.0e-50	189	COG0757	3-dehydroquinate dehydratase	146
644987850	236	32.27	17	227	8	226	6.0e-30	124	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644987851	328	30.24	9	297	7	292	2.0e-11	63.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
644987853	635	38.1	45	632	30	567	3.0e-129	455	COG4232	Thiol:disulfide interchange protein	569
644987854	301	34.02	13	295	27	313	4.0e-46	178	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
644987857	179	30.33	22	141	7	127	9.0e-13	66.8	COG0526	Thiol-disulfide isomerase or thioredoxin	127
644987858	117	38.89	9	116	2	104	1.0e-22	98.4	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
644987859	174	34.71	3	172	2	146	2.0e-29	121	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
644987860	96	63.16	1	95	1	95	1.0e-32	131	COG0234	Co-chaperonin GroES (HSP10)	96
644987861	545	48.09	1	533	2	524	0.0e+00	501	COG0459	Chaperonin GroEL (HSP60 family)	524
644987864	210	43.08	1	192	1	195	3.0e-59	221	COG0288	Carbonic anhydrase	207
644987866	459	28.57	99	326	73	313	3.0e-35	142	COG0226	ABC-type phosphate transport system, periplasmic component	318
644987868	582	25.56	173	561	2	398	8.0e-31	128	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
644987869	229	31.84	45	223	1	178	1.0e-25	109	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644987871	388	31.47	8	290	1	244	1.0e-56	214	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
644987872	519	56.26	4	518	2	517	0.0e+00	540	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
644987873	188	39.77	9	174	6	175	1.0e-43	169	COG3175	Cytochrome c oxidase assembly protein Cox11	195
644987874	291	35.19	59	291	6	206	3.0e-40	159	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
644987875	218	33.91	1	218	3	228	2.0e-36	145	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
644987878	335	26.28	18	330	23	337	7.0e-32	131	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
644987879	438	36.9	115	385	76	343	9.0e-54	204	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
644987880	455	33.33	116	396	59	343	8.0e-54	204	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
644987881	429	34.35	83	376	64	343	1.0e-54	207	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
644987882	118	49.15	1	118	4	121	4.0e-30	122	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
644987883	186	67.97	3	155	12	164	4.0e-77	280	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
644987884	231	43.59	5	199	9	169	5.0e-43	167	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
644987885	417	59.23	1	417	9	398	0.0e+00	609	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
644987886	164	45.22	7	163	2	156	1.0e-47	182	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
644987887	431	60.1	7	416	14	422	0.0e+00	617	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
644987888	747	35.47	1	667	1	612	0.0e+00	513	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
644987889	346	51.04	1	337	4	332	6.0e-92	330	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
644987890	163	40	3	163	2	161	2.0e-41	161	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
644987891	226	48.24	1	170	1	166	1.0e-33	136	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
644987892	100	55	1	100	2	100	5.0e-22	95.9	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
644987893	672	45.1	7	667	1	606	0.0e+00	468	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
644987894	505	50.2	3	502	1	492	0.0e+00	490	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
644987895	476	43.25	4	476	4	474	2.0e-97	349	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
644987897	150	48.3	4	150	7	153	3.0e-41	161	COG0779	Ribosome maturation factor RimP	153
644987898	497	48.98	160	354	1	190	7.0e-48	185	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
644987899	870	64.23	368	870	2	507	0.0e+00	670	COG0532	Translation initiation factor IF-2, a GTPase	509
644987900	122	50.85	1	118	2	118	5.0e-28	116	COG0858	Ribosome-binding factor A	118
644987901	308	38.03	3	303	3	271	9.0e-63	234	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
644987902	184	22.37	8	152	46	192	1.0e-05	43	COG0400	Predicted esterase	207
644987903	89	64.04	1	89	1	89	4.0e-28	116	COG0184	Ribosomal protein S15P/S13E	89
644987904	706	61.53	1	694	2	692	0.0e+00	969	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
644987905	734	31.37	9	505	5	507	7.0e-93	335	COG3227	Zn-dependent metalloprotease	507
644987908	466	24.31	1	452	2	471	3.0e-38	153	COG0591	Na+/proline symporter	493
644987909	446	51.24	1	440	1	436	0.0e+00	551	COG0621	tRNA A37 methylthiotransferase MiaB	437
644987910	346	52.52	1	333	8	344	4.0e-116	411	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
644987911	169	43.12	8	165	2	150	1.0e-33	135	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
644987912	285	51.44	2	278	9	282	4.0e-91	327	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
644987913	505	32.24	1	505	5	512	2.0e-84	306	COG0815	Apolipoprotein N-acyltransferase	518
644987917	881	53.82	10	880	3	814	0.0e+00	1071	COG0495	Leucyl-tRNA synthetase	814
644987918	167	26.99	1	162	1	158	8.0e-11	60.3	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
644987919	364	28.14	3	329	1	334	4.0e-45	175	COG1466	DNA polymerase III, delta subunit	334
644987920	224	37.44	6	214	2	195	6.0e-45	174	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
644987921	115	51.92	1	104	1	104	5.0e-33	132	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
644987922	156	45.81	1	155	1	155	7.0e-56	209	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
644987923	632	34.02	5	625	1	599	4.0e-125	442	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
644987924	374	45.43	14	372	5	375	1.0e-80	293	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
644987925	344	33.53	1	330	1	336	1.0e-71	263	COG2951	Membrane-bound lytic murein transglycosylase B	343
644987926	300	42.79	11	228	6	212	3.0e-44	172	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
644987927	389	44.01	8	389	8	386	2.0e-113	402	COG1686	D-alanyl-D-alanine carboxypeptidase	389
644987928	299	30.39	1	277	1	276	3.0e-53	202	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
644987929	89	45.78	9	89	8	90	8.0e-17	78.4	COG2921	Putative lipoic acid-binding regulatory protein	90
644987930	224	53.59	1	207	5	213	9.0e-79	286	COG0321	Lipoate-protein ligase B	221
644987931	341	64.05	36	340	1	305	0.0e+00	494	COG0320	Lipoate synthase	306
644987932	160	50.93	1	160	1	161	2.0e-42	165	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
644987933	220	28.36	7	192	1	196	5.0e-26	111	COG0625	Glutathione S-transferase	211
644987937	253	33.5	12	208	9	208	1.0e-23	103	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
644987938	215	32.69	9	214	2	208	8.0e-28	117	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644987939	467	30.3	170	464	42	329	2.0e-40	160	COG0642	Signal transduction histidine kinase	336
644987940	232	42.67	2	231	1	229	4.0e-59	221	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644987943	644	43.71	67	621	1	525	0.0e+00	673	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
644987944	282	52.98	1	282	1	285	1.0e-102	366	COG0414	Panthothenate synthetase	285
644987945	264	54.58	5	263	3	263	7.0e-94	337	COG0413	Ketopantoate hydroxymethyltransferase	268
644987946	217	37.75	10	204	5	208	8.0e-42	163	COG1428	Deoxyadenosine/deoxycytidine kinase	216
644987947	176	48.32	11	159	3	151	2.0e-47	181	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
644987948	456	35.56	36	448	2	412	7.0e-83	301	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
644987950	148	58.33	29	148	1	120	2.0e-31	128	COG1734	RNA polymerase-binding transcription factor DksA	120
644987951	241	48.55	1	241	1	231	2.0e-74	272	COG1489	DNA-binding protein, stimulates sugar fermentation	235
644987953	105	29.81	3	105	7	105	4.0e-15	73.1	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
644987956	193	62.57	8	193	8	193	9.0e-70	256	COG0807	GTP cyclohydrolase II	193
644987958	176	24.42	15	168	12	183	7.0e-08	50.4	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644987961	174	20.26	19	166	13	165	2.0e-07	49.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644987964	602	37.22	411	589	2	180	3.0e-37	150	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644987965	183	28.65	3	168	2	177	4.0e-26	111	COG1514	2'-5' RNA ligase	180
644987966	773	38.43	159	717	57	597	0.0e+00	488	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
644987967	142	23.93	20	131	23	138	8.0e-11	59.6	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
644987969	459	24.93	5	362	1	343	3.0e-32	133	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
644987970	425	35.18	13	425	13	401	1.0e-96	346	COG3844	Kynureninase	407
644987972	339	24.55	6	332	9	290	1.0e-27	117	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
644987974	140	33.33	7	137	9	128	6.0e-23	99	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
644987975	161	64.81	1	161	4	165	3.0e-56	211	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
644987976	643	36.13	44	636	7	586	2.0e-128	453	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
644987980	481	43.33	4	481	1	470	0.0e+00	498	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644987981	263	35.5	4	260	1	251	2.0e-39	156	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644987983	100	41.46	8	89	5	86	1.0e-17	81.1	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
644987984	93	30.11	3	93	2	94	2.0e-13	67.6	COG3549	Plasmid maintenance system killer protein	94
644987985	424	62.5	1	423	4	426	0.0e+00	627	COG0001	Glutamate-1-semialdehyde aminotransferase	432
644987986	353	39.94	18	338	3	316	3.0e-84	305	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
644987987	62	60	3	52	1	50	7.0e-14	68.7	COG1773	Rubredoxin	55
644987988	168	29.61	21	155	2	153	2.0e-20	91.9	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
644987991	203	36.65	13	199	15	203	1.0e-38	153	COG3647	Uncharacterized membrane protein YjdF	205
644987992	289	28.57	45	255	1	200	1.0e-27	117	COG0625	Glutathione S-transferase	211
644987993	166	37.58	1	160	17	181	3.0e-24	104	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644987995	109	48.08	8	109	5	108	8.0e-26	108	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
644987997	443	45.05	47	228	1	174	3.0e-52	200	COG0225	Peptide methionine sulfoxide reductase MsrA	174
644987998	289	48.29	1	263	3	262	6.0e-71	261	COG3739	Uncharacterized membrane protein YoaT, DUF817 family	263
644987999	139	45.07	1	139	8	149	1.0e-33	135	COG1981	Uncharacterized membrane protein	149
644988000	591	31.34	6	419	12	421	2.0e-63	237	COG0038	H+/Cl- antiporter ClcA	443
644988002	175	38.58	4	130	15	137	8.0e-20	90	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
644988003	108	55.56	1	108	3	110	3.0e-37	146	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
644988004	368	48.92	1	368	4	370	7.0e-116	410	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
644988006	398	42.01	1	398	1	401	1.0e-111	396	COG0162	Tyrosyl-tRNA synthetase	401
644988015	598	41.04	4	473	25	504	1.0e-119	424	COG0513	Superfamily II DNA and RNA helicase	513
644988017	430	30	51	430	31	402	1.0e-60	227	COG1228	Imidazolonepropionase or related amidohydrolase	406
644988018	346	36.39	7	342	7	290	1.0e-68	253	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
644988019	325	38.98	94	324	4	238	2.0e-50	193	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
644988020	282	24.2	1	268	1	248	6.0e-26	111	COG1521	Pantothenate kinase type III	251
644988025	396	83.08	1	396	1	394	0.0e+00	698	COG0050	Translation elongation factor EF-Tu, a GTPase	394
644988027	123	38.81	52	118	6	72	4.0e-09	53.9	COG0690	Preprotein translocase subunit SecE	73
644988028	177	57.95	1	176	1	176	8.0e-57	212	COG0250	Transcription antitermination factor NusG	178
644988029	142	73.76	2	142	1	140	4.0e-52	196	COG0080	Ribosomal protein L11	141
644988030	231	59.65	1	225	1	228	1.0e-75	276	COG0081	Ribosomal protein L1	228
644988031	175	41.71	1	174	1	175	1.0e-34	139	COG0244	Ribosomal protein L10	175
644988032	125	64.8	1	125	1	124	1.0e-25	108	COG0222	Ribosomal protein L7/L12	124
644988034	1406	52.01	13	854	1	808	0.0e+00	902	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
644988035	124	77.24	1	123	7	129	3.0e-48	183	COG0048	Ribosomal protein S12	129
644988036	157	63.09	2	150	1	148	2.0e-53	201	COG0049	Ribosomal protein S7	148
644988037	699	67.29	1	698	1	691	0.0e+00	1006	COG0480	Translation elongation factor EF-G, a GTPase	697
644988038	396	83.08	1	396	1	394	0.0e+00	698	COG0050	Translation elongation factor EF-Tu, a GTPase	394
644988039	103	71.57	1	102	1	102	5.0e-38	149	COG0051	Ribosomal protein S10	104
644988040	210	61.14	3	210	2	212	2.0e-75	275	COG0087	Ribosomal protein L3	218
644988041	200	48.22	9	200	15	211	5.0e-52	197	COG0088	Ribosomal protein L4	214
644988042	98	54.35	8	98	3	94	2.0e-24	103	COG0089	Ribosomal protein L23	94
644988043	275	68.36	1	274	1	275	1.0e-113	402	COG0090	Ribosomal protein L2	275
644988044	93	67.74	1	93	1	93	8.0e-36	141	COG0185	Ribosomal protein S19	93
644988045	110	60.91	1	110	9	118	3.0e-33	133	COG0091	Ribosomal protein L22	120
644988046	233	60.87	12	233	1	230	3.0e-75	274	COG0092	Ribosomal protein S3	233
644988047	135	60.29	1	132	2	137	1.0e-44	172	COG0197	Ribosomal protein L16/L10AE	146
644988048	63	50	2	61	4	63	2.0e-08	50.6	COG0255	Ribosomal protein L29	69
644988049	85	60.76	7	85	8	86	4.0e-24	102	COG0186	Ribosomal protein S17	87
644988050	122	73.77	1	122	1	122	7.0e-50	188	COG0093	Ribosomal protein L14	122
644988051	105	57.01	1	105	2	103	8.0e-18	81.9	COG0198	Ribosomal protein L24	104
644988052	180	66.29	2	179	1	178	1.0e-75	275	COG0094	Ribosomal protein L5	180
644988053	101	56.67	42	101	2	61	7.0e-18	82.2	COG0199	Ribosomal protein S14	61
644988054	130	58.78	1	129	1	131	3.0e-44	170	COG0096	Ribosomal protein S8	132
644988055	176	57.39	1	175	1	176	9.0e-63	232	COG0097	Ribosomal protein L6P/L9E	178
644988056	117	49.17	1	117	6	125	5.0e-26	109	COG0256	Ribosomal protein L18	125
644988057	167	62.5	7	166	20	179	8.0e-57	212	COG0098	Ribosomal protein S5	181
644988058	60	56.36	6	60	1	55	2.0e-13	67.1	COG1841	Ribosomal protein L30/L7E	55
644988059	145	55.33	1	145	1	150	4.0e-31	126	COG0200	Ribosomal protein L15	152
644988060	446	51.85	5	431	7	432	2.0e-121	429	COG0201	Preprotein translocase subunit SecY	436
644988062	118	61.34	1	118	1	119	5.0e-39	152	COG0099	Ribosomal protein S13	121
644988063	129	72.87	1	129	1	129	4.0e-49	186	COG0100	Ribosomal protein S11	129
644988064	206	62.98	1	206	1	205	7.0e-57	213	COG0522	Ribosomal protein S4 or related protein	205
644988065	326	55.84	6	321	1	314	4.0e-95	341	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
644988066	134	72.41	1	116	1	116	2.0e-47	181	COG0203	Ribosomal protein L17	116
644988069	308	45.97	1	298	1	296	2.0e-76	279	COG1230	Co/Zn/Cd efflux system component	296
644988071	202	41.18	13	194	12	197	1.0e-51	196	COG4764	Uncharacterized protein	197
644988072	417	67.56	7	415	6	412	0.0e+00	664	COG0112	Glycine/serine hydroxymethyltransferase	413
644988073	153	60.78	1	153	1	153	2.0e-56	211	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
644988074	372	61.38	3	147	2	146	3.0e-56	212	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
644988075	202	45.23	1	198	1	196	4.0e-63	234	COG0307	Riboflavin synthase alpha chain	204
644988076	372	58.82	1	204	1	203	5.0e-85	308	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
644988077	161	48.2	17	155	14	152	3.0e-44	171	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
644988078	142	47.62	1	140	1	147	3.0e-33	134	COG0781	Transcription termination factor NusB	151
644988079	323	43.52	1	321	3	317	2.0e-86	312	COG0611	Thiamine monophosphate kinase	317
644988080	157	49.32	8	152	13	159	6.0e-33	133	COG1267	Phosphatidylglycerophosphatase A	160
644988086	619	60.16	6	610	2	616	0.0e+00	926	COG1154	Deoxyxylulose-5-phosphate synthase	627
644988087	296	39.39	5	295	5	321	3.0e-65	242	COG0142	Geranylgeranyl pyrophosphate synthase	322
644988088	81	42.86	5	81	1	77	6.0e-09	52.3	COG1722	Exonuclease VII small subunit	81
644988089	574	31.85	37	546	1	472	2.0e-102	366	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
644988090	615	20.53	1	569	4	619	3.0e-30	127	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
644988093	636	45.03	1	526	1	527	0.0e+00	540	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644988094	197	34.81	1	181	7	184	7.0e-37	146	COG2840	DNA-nicking endonuclease, Smr domain	184
644988096	344	22.11	29	327	14	314	4.0e-26	112	COG3528	Uncharacterized protein	330
644988097	162	40.79	7	157	1	151	9.0e-31	126	COG0782	Transcription elongation factor, GreA/GreB family	151
644988100	192	42.16	5	189	12	180	6.0e-47	180	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
644988101	740	23.77	4	740	16	753	2.0e-87	317	COG4772	Outer membrane receptor for Fe3+-dicitrate	753
644988103	112	34.78	15	105	12	103	1.0e-14	71.5	COG3098	Uncharacterized conserved protein YqcC, DUF446 family	109
644988104	120	33.33	3	119	2	116	2.0e-11	61.2	COG1734	RNA polymerase-binding transcription factor DksA	120
644988105	135	46.59	20	107	3	88	7.0e-23	99.6	COG3695	Alkylated DNA nucleotide flippase Atl1, participates in nucleotide excision repair, Ada-like DNA-binding domain	103
644988110	448	41.36	7	446	2	456	4.0e-110	391	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644988111	176	36.16	1	176	4	177	7.0e-34	136	COG3038	Cytochrome b561	181
644988112	283	31.37	10	279	3	239	2.0e-53	202	COG0688	Phosphatidylserine decarboxylase	239
644988113	335	41.28	38	328	3	290	1.0e-75	277	COG1162	Putative ribosome biogenesis GTPase RsgA	301
644988114	122	41.67	14	109	1	95	8.0e-20	89.2	COG2154	Pterin-4a-carbinolamine dehydratase	101
644988115	182	70.39	1	179	1	179	1.0e-83	302	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
644988116	502	34.64	225	502	15	283	5.0e-51	195	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
644988117	159	45.95	4	151	1	148	4.0e-40	157	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
644988118	440	34.66	100	376	2	228	3.0e-48	186	COG0860	N-acetylmuramoyl-L-alanine amidase	231
644988119	586	36.87	3	532	4	571	0.0e+00	461	COG0323	DNA mismatch repair ATPase MutL	638
644988120	317	52.65	10	311	2	301	3.0e-107	381	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
644988121	114	67.53	1	76	1	77	9.0e-27	111	COG1923	sRNA-binding regulator protein Hfq	77
644988122	433	50.38	8	404	3	394	1.0e-121	430	COG2262	50S ribosomal subunit-associated GTPase HflX	411
644988123	355	29.3	60	324	5	274	8.0e-42	164	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
644988124	294	29.27	4	283	3	278	7.0e-37	147	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
644988125	61	38.33	1	60	1	60	5.0e-08	49.5	COG3242	Uncharacterized conserved protein YjeT, DUF2065 family	62
644988126	433	62.09	4	432	3	430	0.0e+00	636	COG0104	Adenylosuccinate synthase	430
644988127	390	29.92	6	383	10	379	9.0e-52	197	COG2311	Uncharacterized membrane protein YeiB	394
644988129	267	41.25	10	246	13	243	2.0e-46	179	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
644988130	222	19.51	1	221	8	234	2.0e-06	46	COG3208	Surfactin synthase thioesterase subunit	244
644988132	157	35.29	2	153	1	153	2.0e-19	88.9	COG5528	Uncharacterized membrane protein	155
644988134	189	34.09	1	132	3	131	7.0e-26	110	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
644988135	496	26.03	16	491	32	489	2.0e-65	243	COG2939	Carboxypeptidase C (cathepsin A)	498
644988137	476	73.46	6	475	8	478	0.0e+00	686	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
644988138	207	56.42	1	197	1	218	2.0e-84	304	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
644988140	303	22.82	83	225	5	150	1.0e-15	77.7	COG2010	Cytochrome c, mono- and diheme variants	150
644988141	469	35.78	25	430	1	375	1.0e-79	290	COG0348	Polyferredoxin	386
644988142	170	32.24	10	158	3	149	9.0e-27	113	COG3198	Uncharacterized protein	172
644988143	811	36.23	100	808	3	713	0.0e+00	595	COG2217	Cation transport ATPase	713
644988144	68	41.27	1	63	1	58	9.0e-09	51.8	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
644988145	242	37.72	9	224	5	230	7.0e-32	130	COG2836	Sulfite exporter TauE/SafE	232
644988146	335	34.82	1	331	6	310	3.0e-81	295	COG0078	Ornithine carbamoyltransferase	310
644988147	403	39.66	1	399	2	402	1.0e-105	377	COG0137	Argininosuccinate synthase	403
644988148	367	26.57	4	364	10	403	3.0e-42	166	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644988149	440	32.7	36	285	2	263	2.0e-50	193	COG0548	Acetylglutamate kinase	265
644988150	316	34.38	7	315	1	344	7.0e-72	264	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
644988151	443	36.39	12	402	2	388	4.0e-100	358	COG0165	Argininosuccinate lyase	459
644988152	458	41.15	14	447	1	415	4.0e-124	438	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
644988153	237	35.82	24	223	12	212	5.0e-36	144	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
644988156	166	27.56	9	161	12	165	2.0e-18	85.4	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
644988157	487	52.97	16	486	1	464	0.0e+00	585	COG2870	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase	467
644988159	805	48.31	20	727	2	705	0.0e+00	719	COG0557	Exoribonuclease R	706
644988160	246	41.06	1	244	20	257	2.0e-61	229	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
644988163	317	39.09	3	306	1	306	3.0e-85	308	COG1984	Allophanate hydrolase subunit 2	314
644988164	230	49.77	11	225	5	219	2.0e-66	245	COG2049	Allophanate hydrolase subunit 1	223
644988165	252	38.62	7	252	4	249	6.0e-66	243	COG1540	Lactam utilization protein B (function unknown)	252
644988166	407	27.94	8	407	20	416	2.0e-43	170	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
644988167	330	60.62	7	325	3	322	8.0e-127	446	COG2502	Asparagine synthetase A	330
644988168	156	31.97	6	151	5	151	7.0e-27	113	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644988170	327	23.67	7	324	61	393	4.0e-08	52.5	COG1459	Type II secretory pathway, component PulF	397
644988172	134	45.05	2	111	1	111	9.0e-31	125	COG0360	Ribosomal protein S6	112
644988173	75	69.12	1	68	8	75	1.0e-22	98	COG0238	Ribosomal protein S18	75
644988174	151	53.69	1	149	1	148	2.0e-40	158	COG0359	Ribosomal protein L9	148
644988175	132	31.58	1	131	2	131	2.0e-16	78.5	COG3791	Uncharacterized conserved protein	133
644988177	132	37.88	1	132	6	137	1.0e-31	128	COG3011	Predicted thiol-disulfide oxidoreductase YuxK, DCC family	137
644988181	461	47.85	15	453	1	435	0.0e+00	503	COG0305	Replicative DNA helicase	435
644988182	364	47.09	1	357	2	358	4.0e-114	404	COG0787	Alanine racemase	360
644988183	137	40.15	1	136	2	136	3.0e-37	147	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
644988185	298	30.36	1	298	15	296	2.0e-44	172	COG0501	Zn-dependent protease with chaperone function	302
644988187	330	34.24	5	326	9	321	2.0e-72	266	COG0042	tRNA-dihydrouridine synthase	323
644988191	394	44.53	149	392	80	315	8.0e-63	234	COG2829	Outer membrane phospholipase A	317
644988192	475	21.26	13	468	10	403	3.0e-24	106	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644988193	286	22.17	33	232	22	223	2.0e-16	79.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644988194	244	44.02	39	244	57	263	5.0e-59	220	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
644988195	143	31.65	7	143	6	144	9.0e-26	109	COG2847	Copper(I)-binding protein	151
644988196	340	27.19	24	337	31	356	3.0e-54	205	COG5345	Uncharacterized protein	358
644988197	182	35.43	15	182	3	177	2.0e-28	118	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644988199	176	56	1	175	1	171	1.0e-54	205	COG0221	Inorganic pyrophosphatase	171
644988200	667	47	1	667	2	699	0.0e+00	615	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
644988202	495	29.59	117	284	47	209	1.0e-22	101	COG0705	Membrane associated serine protease, rhomboid family	228
644988204	421	25.59	10	384	7	344	3.0e-46	179	COG0205	6-phosphofructokinase	347
644988205	451	42.55	2	450	9	459	0.0e+00	473	COG0773	UDP-N-acetylmuramate-alanine ligase	459
644988206	216	46.19	16	212	3	187	4.0e-65	241	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
644988207	310	36.63	1	302	1	292	2.0e-74	272	COG1131	ABC-type multidrug transport system, ATPase component	293
644988208	253	19.64	25	247	43	256	3.0e-07	49.4	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
644988209	197	27.89	9	189	11	200	2.0e-24	105	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
644988213	393	57.61	1	393	1	391	0.0e+00	516	COG3007	Trans-2-enoyl-CoA reductase	398
644988215	639	23.16	2	638	13	642	9.0e-64	238	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
644988218	388	44.25	98	377	2	283	1.0e-85	310	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
644988219	348	41.38	1	345	2	339	1.0e-111	396	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
644988220	460	37.77	1	460	26	486	4.0e-109	388	COG0513	Superfamily II DNA and RNA helicase	513
644988223	422	18.8	1	412	1	362	4.0e-13	69.7	COG1106	ATPase/GTPase, AAA15 family	371
644988227	363	63.17	1	363	1	372	0.0e+00	512	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
644988228	197	52.91	3	191	1	188	5.0e-69	253	COG0193	Peptidyl-tRNA hydrolase	190
644988229	229	45.26	3	97	1	93	6.0e-23	101	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
644988230	316	57.78	1	314	2	313	3.0e-119	421	COG0462	Phosphoribosylpyrophosphate synthetase	314
644988232	295	41.26	17	293	5	286	2.0e-77	282	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
644988233	208	25.24	1	206	4	205	4.0e-26	111	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
644988235	420	44.79	1	419	1	414	2.0e-117	416	COG0373	Glutamyl-tRNA reductase	414
644988236	364	67.49	2	362	1	363	0.0e+00	557	COG0216	Protein chain release factor A	363
644988237	286	43.51	4	285	1	278	1.0e-68	253	COG2890	Methylase of polypeptide chain release factors	280
644988238	347	65.99	5	346	1	342	0.0e+00	469	COG1077	Actin-like ATPase involved in cell morphogenesis	342
644988239	262	34.01	1	244	24	270	4.0e-44	171	COG1792	Cell shape-determining protein MreC	284
644988240	165	33.33	10	164	7	162	2.0e-17	82.2	COG2891	Cell shape-determining protein MreD	167
644988241	205	47.62	1	188	1	187	2.0e-58	218	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
644988242	498	45.47	4	498	3	483	0.0e+00	470	COG1530	Ribonuclease G or E	487
644988243	1319	20.28	9	1253	1	1267	4.0e-97	350	COG3164	Uncharacterized conserved protein YhdP, contains DUF3971 and AsmA2 domains	1271
644988244	273	32.6	3	270	1	263	1.0e-55	210	COG0388	Predicted amidohydrolase	274
644988245	478	38.96	21	476	3	454	8.0e-118	417	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
644988246	171	42.33	3	165	18	180	3.0e-33	134	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
644988247	702	20.64	2	650	6	626	1.0e-31	131	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
644988248	454	35.92	26	453	4	452	1.0e-74	273	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
644988249	459	37.39	7	458	2	447	5.0e-109	388	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
644988250	283	46.69	1	282	1	286	3.0e-91	328	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
644988251	169	28.29	3	152	2	152	3.0e-18	85	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
644988252	95	57.73	1	95	1	97	1.0e-24	104	COG1544	Ribosome-associated translation inhibitor RaiA	110
644988253	495	36.46	1	490	1	441	6.0e-100	358	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
644988254	241	69.01	1	241	2	243	1.0e-105	376	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
644988256	185	24.42	12	182	11	180	1.0e-15	76.5	COG3117	Lipopolysaccharide export system protein LptC	188
644988257	193	57.06	14	183	1	170	1.0e-62	232	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
644988258	326	57.43	10	210	1	202	8.0e-66	244	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
644988259	327	42.2	1	327	8	319	3.0e-49	189	COG0530	Ca2+/Na+ antiporter	320
644988260	81	55.26	3	78	4	79	4.0e-22	96.1	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
644988261	419	66.03	1	418	1	418	0.0e+00	634	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
644988262	388	35.11	37	385	14	339	1.0e-51	197	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
644988264	228	36.23	1	205	1	201	5.0e-36	144	COG3647	Uncharacterized membrane protein YjdF	205
644988266	212	45.5	7	204	8	204	2.0e-52	199	COG2945	Alpha/beta superfamily hydrolase	210
644988267	367	52.63	7	366	10	367	0.0e+00	464	COG1485	Predicted ATPase	367
644988269	113	33.33	17	112	3	90	1.0e-05	41.7	COG0776	Bacterial nucleoid DNA-binding protein	94
644988270	142	65.03	1	142	1	143	5.0e-56	209	COG0102	Ribosomal protein L13	148
644988271	129	66.67	1	129	2	130	8.0e-48	182	COG0103	Ribosomal protein S9	130
644988272	195	32.29	1	192	2	168	2.0e-27	115	COG0723	Rieske Fe-S protein	177
644988273	403	49.48	1	385	3	373	6.0e-87	314	COG1290	Cytochrome b subunit of the bc complex	381
644988274	281	28.87	1	281	6	250	4.0e-43	168	COG2857	Cytochrome c1	250
644988275	210	33	10	194	1	198	1.0e-30	126	COG0625	Glutathione S-transferase	211
644988276	155	46.36	5	155	6	155	2.0e-39	155	COG2969	Stringent starvation protein B	155
644988277	175	35.95	25	175	44	196	1.0e-24	106	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
644988278	195	63.13	1	179	1	176	7.0e-67	246	COG0279	Phosphoheptose isomerase	176
644988279	122	41.88	3	119	1	114	6.0e-33	132	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
644988280	612	27.35	1	610	2	603	9.0e-87	315	COG3107	Outer membrane lipoprotein LpoA, binds and activates PBP1a	604
644988281	288	51.46	15	287	5	275	3.0e-91	328	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
644988284	316	49.35	1	304	4	309	1.0e-109	389	COG2066	Glutaminase	309
644988285	151	42.96	1	142	1	140	3.0e-39	154	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
644988286	311	54.46	1	310	1	312	6.0e-113	400	COG0275	16S rRNA C1402 N4-methylase RsmH	314
644988287	119	37.8	32	113	24	105	6.0e-12	63	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
644988288	586	36.05	3	565	1	597	5.0e-121	428	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
644988289	533	37.28	30	532	5	475	3.0e-116	412	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
644988290	465	45.71	2	451	1	450	6.0e-120	424	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
644988291	359	45.95	20	359	1	316	1.0e-56	213	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
644988292	444	43.18	9	444	8	446	2.0e-113	402	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
644988293	408	43.73	18	386	6	374	1.0e-85	310	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
644988294	372	43.25	3	362	1	357	3.0e-96	345	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
644988295	489	53.45	15	475	1	455	0.0e+00	606	COG0773	UDP-N-acetylmuramate-alanine ligase	459
644988296	312	42.59	5	308	1	317	4.0e-75	274	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
644988297	262	24.61	7	257	15	265	1.0e-27	117	COG1589	Cell division septal protein FtsQ	269
644988298	408	53.16	8	408	6	417	0.0e+00	473	COG0849	Cell division ATPase FtsA	418
644988299	391	60.13	12	322	9	319	3.0e-100	358	COG0206	Cell division GTPase FtsZ	338
644988300	304	65.17	1	289	1	290	4.0e-126	444	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
644988302	306	29.36	83	305	28	262	2.0e-28	120	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
644988303	903	60.09	1	892	2	820	0.0e+00	1097	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
644988304	133	24.19	1	119	6	128	8.0e-08	49.6	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
644988305	65	50.91	1	55	2	56	6.0e-13	65.8	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
644988307	291	48.06	10	290	2	278	9.0e-87	313	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
644988308	101	41.67	1	96	1	95	2.0e-16	77.3	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
644988310	569	17.21	8	407	19	405	3.0e-07	50.5	COG3307	O-antigen ligase	424
644988311	570	46.83	69	570	6	500	0.0e+00	560	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
644988312	414	41.71	17	414	1	396	2.0e-110	392	COG1459	Type II secretory pathway, component PulF	397
644988313	302	41.44	11	301	2	254	6.0e-35	141	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
644988314	199	46.73	1	199	1	199	2.0e-52	198	COG0237	Dephospho-CoA kinase	201
644988315	255	35.48	8	255	2	244	9.0e-47	180	COG4582	Cell division protein ZapD, interacts with FtsZ	244
644988316	289	25.23	1	211	1	210	6.0e-14	71.9	COG3725	Membrane protein required for beta-lactamase induction	282
644988317	898	69.31	17	897	7	886	0.0e+00	1410	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
644988318	559	43.5	138	559	5	403	1.0e-100	360	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
644988319	472	52.2	5	455	4	454	0.0e+00	500	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
644988320	313	21.93	11	304	8	285	2.0e-09	57.1	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
644988321	763	23.88	172	763	58	618	9.0e-60	225	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
644988322	364	26.61	22	363	49	399	6.0e-58	218	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
644988323	697	48.62	52	697	7	654	0.0e+00	747	COG3590	Predicted metalloendopeptidase	654
644988324	151	29.93	11	146	1	135	1.0e-21	95.7	COG0824	Acyl-CoA thioesterase FadM	137
644988325	305	32.53	19	264	1	242	4.0e-49	188	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
644988326	409	54.5	1	200	1	193	4.0e-56	212	COG2715	Spore maturation protein SpmA (function unknown)	206
644988329	358	46.05	7	355	5	358	8.0e-101	360	COG2933	23S rRNA C2498 (ribose-2'-O)-methylase RlmM	358
644988330	278	53.38	2	133	4	136	3.0e-46	178	COG2904	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, N-terminal domain	137
644988331	624	41.21	18	624	3	587	0.0e+00	506	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
644988332	568	41.62	10	563	2	509	0.0e+00	504	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
644988333	237	36.24	9	230	15	241	1.0e-54	206	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
644988334	484	57.32	215	460	1	244	2.0e-91	330	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
644988335	575	40.61	184	575	117	498	3.0e-74	273	COG3104	Dipeptide/tripeptide permease	498
644988336	207	29.02	8	197	5	194	1.0e-29	123	COG3145	Alkylated DNA repair dioxygenase AlkB	194
644988337	344	25.4	34	341	16	324	7.0e-51	194	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
644988339	1138	22.4	1	1129	1	1129	4.0e-85	310	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
644988340	180	28.65	5	177	4	181	5.0e-24	103	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644988341	616	38.16	32	609	1	586	0.0e+00	535	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
644988342	172	18.9	34	159	9	127	4.0e-06	44.6	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
644988343	365	66.53	128	365	1	239	3.0e-99	355	COG1186	Protein chain release factor B	239
644988344	499	60.44	1	499	1	501	0.0e+00	720	COG1190	Lysyl-tRNA synthetase (class II)	502
644988346	615	38.78	30	609	1	588	0.0e+00	530	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
644988347	214	22.54	35	207	1	153	1.0e-17	83.4	COG1225	Peroxiredoxin	157
644988348	312	30.11	28	305	17	282	1.0e-45	176	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
644988349	84	39.24	1	78	10	88	3.0e-15	73.7	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
644988351	537	56.27	15	537	8	514	0.0e+00	691	COG0029	Aspartate oxidase	518
644988352	196	32.09	6	192	1	181	2.0e-33	135	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644988353	232	21.18	11	162	1	170	1.0e-06	47.3	COG3073	Negative regulator of sigma E activity	213
644988355	163	30.46	6	156	1	149	8.0e-26	109	COG3086	Positive regulator of sigma E activity	150
644988356	432	44.88	10	329	12	340	9.0e-65	241	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
644988357	602	70.85	5	600	7	603	0.0e+00	1063	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
644988360	229	54.05	7	223	7	227	4.0e-67	247	COG0571	dsRNA-specific ribonuclease	235
644988361	299	53.87	3	298	2	297	1.0e-114	406	COG1159	GTPase Era, involved in 16S rRNA processing	298
644988362	239	34.15	1	237	2	246	6.0e-33	134	COG1381	Recombinational DNA repair protein (RecF pathway)	251
644988363	249	66.94	5	243	1	242	2.0e-94	338	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
644988364	127	52	1	125	1	125	3.0e-36	143	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
644988366	276	33.65	3	211	2	202	5.0e-34	138	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644988367	161	62.5	1	160	2	161	1.0e-67	248	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
644988368	464	18.73	57	441	4	382	1.0e-21	98.1	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
644988369	161	30.43	10	145	5	139	7.0e-16	76.8	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
644988370	91	40.96	1	83	6	88	1.0e-08	51.3	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
644988371	124	34.26	2	108	1	108	8.0e-19	86.1	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
644988372	321	21.83	173	310	11	152	1.0e-06	47.7	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
644988373	121	39.45	9	114	6	113	3.0e-17	80.6	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
644988374	492	36.55	2	471	1	471	8.0e-59	221	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
644988375	506	30.08	8	498	1	480	1.0e-54	208	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
644988377	563	29.81	1	443	2	484	3.0e-48	186	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
644988381	240	26.67	1	234	3	240	5.0e-38	151	COG2186	DNA-binding transcriptional regulator, FadR family	241
644988383	384	35.71	135	375	60	310	3.0e-50	192	COG0616	Periplasmic serine protease, ClpP class	317
644988385	629	28.15	165	628	162	617	2.0e-64	240	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
644988387	436	42.42	1	426	6	407	6.0e-90	324	COG1301	Na+/H+-dicarboxylate symporter	415
644988388	125	43.33	4	122	3	122	7.0e-25	106	COG3682	Predicted transcriptional regulator	123
644988389	671	25.96	18	299	13	324	3.0e-33	137	COG4219	Signal transducer regulating beta-lactamase production, contains  metallopeptidase domain	337
644988390	456	58.71	7	454	2	440	0.0e+00	596	COG3724	Succinylarginine dihydrolase	442
644988391	491	36.38	9	463	3	455	1.0e-103	370	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644988392	340	50.6	1	336	2	336	2.0e-118	418	COG3138	Arginine/ornithine N-succinyltransferase beta subunit	336
644988393	406	53	5	403	3	397	0.0e+00	543	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
644988394	224	42.92	7	224	2	213	2.0e-44	172	COG3047	Outer membrane protein W	213
644988395	211	39.52	23	208	4	213	3.0e-27	115	COG2755	Lysophospholipase L1 or related esterase	216
644988396	244	61.88	4	224	6	228	3.0e-81	294	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
644988397	832	35.91	1	832	3	829	0.0e+00	603	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
644988398	876	46.57	3	606	1	570	0.0e+00	646	COG0550	DNA topoisomerase IA	570
644988399	342	43.67	45	337	3	290	2.0e-84	306	COG0167	Dihydroorotate dehydrogenase	310
644988400	718	38.28	1	383	3	377	1.0e-102	368	COG0116	23S rRNA G2445 N2-methylase RlmL	381
644988404	823	28.82	124	511	5	382	9.0e-50	192	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644988405	384	51.83	5	384	1	377	7.0e-118	417	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
644988407	152	29.63	10	152	14	173	3.0e-16	77.7	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
644988409	434	18.91	57	402	1	316	3.0e-22	99	COG0668	Small-conductance mechanosensitive channel	316
644988410	529	70.36	9	529	6	528	0.0e+00	879	COG4108	Peptide chain release factor RF-3	528
644988411	265	41.8	11	264	1	256	2.0e-65	242	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
644988413	587	43.15	90	584	16	500	0.0e+00	495	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
644988414	496	44.13	28	484	11	467	1.0e-126	447	COG4623	Membrane-bound lytic murein transglycosylase MltF	473
644988415	1298	36.32	162	990	2	743	0.0e+00	730	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
644988420	252	28	23	240	16	239	2.0e-46	178	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644988421	522	46.05	5	521	3	518	0.0e+00	509	COG2918	Gamma-glutamylcysteine synthetase	518
644988422	529	44.8	18	511	7	487	3.0e-86	312	COG0591	Na+/proline symporter	493
644988424	393	70.56	1	393	1	394	0.0e+00	612	COG0027	Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	394
644988425	140	39.29	9	140	7	146	2.0e-21	95.1	COG0071	Molecular chaperone IbpA, HSP20 family	146
644988426	151	33.56	1	144	2	150	5.0e-16	76.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
644988427	830	22.01	10	827	2	726	2.0e-79	291	COG1033	Predicted exporter protein, RND superfamily	727
644988428	426	50.36	5	416	1	415	0.0e+00	475	COG4536	Mg2+ and Co2+ transporter CorB, contains DUF21, CBS pair, and CorC-HlyC domains	423
644988429	263	26.24	1	262	3	265	2.0e-22	99.5	COG4137	ABC-type uncharacterized transport system, permease component	265
644988430	466	62.78	1	454	1	451	0.0e+00	606	COG0541	Signal recognition particle GTPase	451
644988432	105	45.19	1	104	2	88	4.0e-21	92.8	COG3809	Predicted nucleic acid-binding protein, contains Zn-finger domain	88
644988433	81	61.73	1	81	1	80	1.0e-25	108	COG0228	Ribosomal protein S16	87
644988434	173	44.12	1	168	1	169	8.0e-44	169	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
644988435	255	52.85	1	245	1	239	5.0e-97	347	COG0336	tRNA G37 N-methylase TrmD	240
644988436	118	68.75	3	114	4	115	4.0e-40	156	COG0335	Ribosomal protein L19	115
644988437	295	54.21	1	295	4	300	4.0e-107	381	COG4974	Site-specific recombinase XerD	300
644988438	252	21.18	1	249	4	244	3.0e-22	98.7	COG1651	Protein-disulfide isomerase	244
644988440	584	41.11	41	560	1	491	1.0e-107	383	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
644988442	279	36.33	22	279	36	302	2.0e-40	159	COG0668	Small-conductance mechanosensitive channel	316
644988443	447	33.56	1	430	3	436	6.0e-104	371	COG0621	tRNA A37 methylthiotransferase MiaB	437
644988444	950	34.21	267	531	81	334	1.0e-41	165	COG0642	Signal transduction histidine kinase	336
644988447	448	34.17	13	441	3	432	4.0e-105	375	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
644988449	242	42.17	1	242	19	265	1.0e-34	140	COG0428	Zinc transporter ZupT	266
644988450	736	47.17	17	733	7	700	0.0e+00	740	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
644988453	147	55.1	1	147	2	146	1.0e-50	192	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
644988454	545	63.94	2	537	1	528	0.0e+00	884	COG0504	CTP synthase (UTP-ammonia lyase)	533
644988455	286	59.85	1	274	5	278	4.0e-120	424	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
644988456	424	68.88	2	422	3	420	0.0e+00	653	COG0148	Enolase	423
644988457	107	40	1	90	24	113	7.0e-13	65.7	COG2919	Cell division protein FtsB	117
644988458	232	45.54	5	226	2	222	2.0e-64	239	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
644988459	282	32.76	1	282	1	289	4.0e-55	208	COG0040	ATP phosphoribosyltransferase	290
644988460	560	31.96	8	342	22	352	3.0e-55	209	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
644988461	198	48.17	10	198	5	195	1.0e-63	236	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
644988462	202	38.19	11	199	2	198	1.0e-46	179	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
644988463	265	55.21	4	261	1	256	1.0e-88	319	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
644988464	412	29.66	1	223	3	238	9.0e-43	168	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
644988465	405	37.41	21	404	22	420	2.0e-99	356	COG0141	Histidinol dehydrogenase	425
644988466	162	58.23	2	159	1	158	1.0e-58	218	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
644988467	351	31.22	13	351	17	405	4.0e-57	215	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
644988468	256	53.17	1	246	1	252	7.0e-87	313	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
644988469	222	50	19	221	5	206	3.0e-64	238	COG2518	Protein-L-isoaspartate O-methyltransferase	209
644988470	194	33.95	3	163	1	158	9.0e-22	96.9	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
644988471	334	29.89	68	334	4	267	7.0e-33	134	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
644988473	87	46.43	4	87	2	83	1.0e-16	78.5	COG0271	Stress-induced morphogen (activity unknown)	90
644988474	99	46.94	1	98	1	92	7.0e-22	95.4	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
644988475	219	29.19	25	209	1	180	2.0e-17	82.9	COG2917	Intracellular septation protein A	180
644988476	276	39.13	1	252	2	250	1.0e-43	170	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
644988477	207	42.51	2	207	1	205	1.0e-56	212	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
644988478	124	33.33	4	121	11	127	6.0e-17	79.6	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
644988479	158	38.64	20	142	12	136	9.0e-29	119	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
644988480	119	50.86	4	119	3	117	3.0e-34	137	COG5507	Uncharacterized  conserved protein YbaA, DUF1428 family	117
644988481	205	28.78	1	198	1	200	6.0e-27	114	COG0625	Glutathione S-transferase	211
644988482	133	33.33	20	128	1	111	1.0e-08	52.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
644988483	391	33.16	1	370	12	314	1.0e-80	294	COG0180	Tryptophanyl-tRNA synthetase	314
644988484	305	42.8	47	283	1	243	4.0e-48	185	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
644988485	312	54.12	8	176	11	176	1.0e-41	163	COG1386	Chromosome segregation and condensation protein ScpB	184
644988487	267	47.01	1	244	1	247	2.0e-67	249	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
644988488	711	52.19	35	691	8	664	0.0e+00	846	COG0855	Polyphosphate kinase	696
644988489	518	37.7	26	505	5	491	1.0e-104	373	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
644988490	249	35.48	11	244	3	246	2.0e-44	172	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644988491	230	41.56	3	229	1	227	7.0e-48	183	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644988492	670	21.47	328	650	3	317	1.0e-21	98.7	COG0642	Signal transduction histidine kinase	336
644988494	221	33.78	3	221	2	220	2.0e-39	155	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
644988495	239	56.54	5	238	6	241	1.0e-87	316	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
644988496	444	36.93	5	412	2	404	8.0e-84	304	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
644988497	879	57.04	1	841	1	802	0.0e+00	1040	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
644988498	361	52.49	1	360	3	363	1.0e-124	439	COG1932	Phosphoserine aminotransferase	365
644988499	102	59.26	1	81	1	75	9.0e-21	91.6	COG3813	Uncharacterized protein	84
644988500	731	53.24	49	728	5	680	0.0e+00	855	COG1770	Protease II	682
644988501	366	39.44	8	363	1	350	6.0e-94	338	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
644988502	228	53.67	6	222	2	215	2.0e-71	262	COG0283	Cytidylate kinase	222
644988503	555	58.62	1	550	1	540	0.0e+00	599	COG0539	Ribosomal protein S1	541
644988504	100	49.45	1	91	2	91	2.0e-29	120	COG0776	Bacterial nucleoid DNA-binding protein	94
644988505	97	26.67	1	90	1	90	2.0e-07	48	COG3771	Uncharacterized membrane protein YciS, DUF1049 family	97
644988506	391	43.08	4	391	5	389	2.0e-113	402	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
644988507	231	50.22	1	229	9	234	7.0e-70	257	COG0284	Orotidine-5'-phosphate decarboxylase	240
644988509	206	22.95	23	199	47	224	3.0e-07	48.6	COG0705	Membrane associated serine protease, rhomboid family	228
644988513	496	32.89	1	489	8	534	1.0e-102	367	COG0659	Sulfate permease or related transporter, MFS superfamily	554
644988514	283	19.18	164	283	6	151	6.0e-07	48.4	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
644988516	392	43.54	8	391	2	388	2.0e-109	389	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
644988517	662	66.62	1	661	1	661	0.0e+00	1083	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
644988518	213	23.74	6	201	9	202	3.0e-12	65.3	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
644988519	167	28	5	166	2	176	8.0e-25	106	COG0250	Transcription antitermination factor NusG	178
644988520	267	46.59	8	262	6	263	4.0e-73	268	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
644988521	911	27.27	117	306	23	219	4.0e-23	104	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
644988523	328	20.45	9	324	3	346	4.0e-16	79.2	COG3765	LPS O-antigen chain length determinant protein, WzzB/FepE family	347
644988524	338	33.23	3	304	7	313	4.0e-31	128	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
644988525	371	59.14	1	369	4	368	0.0e+00	494	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
644988526	417	49.65	5	416	11	423	0.0e+00	506	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
644988527	163	29.93	15	158	28	173	1.0e-18	86.1	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
644988529	432	18.96	1	422	5	419	3.0e-15	76.7	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
644988534	352	24.47	5	350	2	381	1.0e-27	117	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644988538	240	36.07	5	240	7	249	5.0e-50	191	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
644988539	302	36.18	7	302	17	261	8.0e-56	211	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
644988540	473	62.3	19	453	1	431	0.0e+00	629	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
644988541	582	17.62	111	581	57	458	2.0e-19	90.8	COG0471	Di- and tricarboxylate transporter	461
644988542	198	66.84	3	198	1	196	3.0e-90	324	COG0529	Adenylylsulfate kinase or related kinase	197
644988544	211	54.5	1	211	1	211	4.0e-84	304	COG0177	Endonuclease III	211
644988545	233	65.4	4	214	2	212	4.0e-76	277	COG4660	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfE subunit	212
644988546	213	44.39	4	199	2	195	2.0e-52	198	COG4659	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit	195
644988547	358	53.04	5	349	6	338	6.0e-100	357	COG4658	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfD subunit	338
644988548	539	50.1	12	527	3	513	0.0e+00	526	COG4656	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfC subunit	529
644988549	195	62.36	1	176	2	179	7.0e-63	233	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
644988550	193	80.83	1	193	1	193	3.0e-68	251	COG4657	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfA subunit	193
644988552	212	40.95	2	210	1	210	4.0e-49	187	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644988553	612	48.01	11	610	1	581	0.0e+00	621	COG0322	Excinuclease UvrABC, nuclease subunit	581
644988554	188	41.62	1	185	11	192	3.0e-24	104	COG0558	Phosphatidylglycerophosphate synthase	192
644988558	606	37.42	3	604	2	550	0.0e+00	472	COG3975	Predicted metalloprotease, contains C-terminal PDZ domain	558
644988559	271	40.81	1	269	1	261	7.0e-78	284	COG0708	Exonuclease III	261
644988562	335	31.83	5	331	1	309	5.0e-42	165	COG0524	Sugar or nucleoside kinase, ribokinase family	311
644988563	152	36.05	1	138	2	139	5.0e-20	90.3	COG2062	Phosphohistidine phosphatase SixA	163
644988564	262	28.99	27	260	2	230	6.0e-23	101	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
644988565	304	35.99	16	302	2	279	4.0e-55	208	COG2890	Methylase of polypeptide chain release factors	280
644988566	181	46.91	8	165	3	163	1.0e-41	162	COG3101	Elongation factor P hydroxylase (EF-P beta-lysylation pathway)	180
644988567	373	39.57	1	371	1	355	3.0e-73	269	COG3199	Predicted polyphosphate- or ATP-dependent NAD kinase	355
644988568	187	33.86	4	177	2	189	9.0e-35	140	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
644988569	630	40.15	1	397	2	390	5.0e-62	232	COG0475	Kef-type K+ transport system, membrane component KefB	397
644988570	238	39.53	1	237	1	250	2.0e-37	149	COG0390	ABC-type iron transport system FetAB, permease component	256
644988571	290	38.19	1	287	2	276	2.0e-60	225	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
644988574	635	33.62	32	259	19	241	4.0e-47	183	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
644988575	185	56.59	4	185	14	195	2.0e-74	271	COG0302	GTP cyclohydrolase I	195
644988576	361	30.75	1	289	2	318	6.0e-46	178	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
644988578	69	61.54	6	69	3	67	7.0e-21	92.1	COG1278	Cold shock protein, CspA family	67
644988579	458	33.04	10	458	36	493	5.0e-97	348	COG0513	Superfamily II DNA and RNA helicase	513
644988580	83	52.94	12	79	3	70	2.0e-16	77.6	COG3530	Uncharacterized conserved protein, DUF3820 family	71
644988581	422	32.96	61	417	3	312	6.0e-65	241	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
644988584	288	30.48	1	286	1	289	3.0e-38	152	COG0583	DNA-binding transcriptional regulator, LysR family	297
644988585	477	55.53	2	467	1	422	0.0e+00	605	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
644988586	213	54.72	1	212	1	191	9.0e-75	273	COG0066	3-isopropylmalate dehydratase small subunit	191
644988587	358	52.34	1	358	2	346	2.0e-124	438	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
644988588	208	42.11	6	195	3	191	4.0e-43	167	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
644988589	223	49.11	1	223	3	221	9.0e-40	156	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
644988590	251	39.75	1	241	31	272	5.0e-37	147	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
644988592	163	46.9	1	145	1	145	2.0e-41	161	COG2332	Cytochrome c-type biogenesis protein CcmE	153
644988593	662	51.46	1	648	1	644	0.0e+00	656	COG1138	Cytochrome c biogenesis factor	648
644988594	188	21.88	33	157	2	127	2.0e-08	52.2	COG0526	Thiol-disulfide isomerase or thioredoxin	127
644988595	148	42.22	1	133	2	136	7.0e-34	136	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
644988598	281	53.7	7	273	3	272	4.0e-88	317	COG3220	Uncharacterized conserved protein, UPF0276 family	282
644988599	261	28.69	12	261	6	235	4.0e-34	138	COG3219	Uncharacterized protein	237
644988600	242	42.68	1	241	3	246	7.0e-70	257	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
644988603	298	49.66	4	298	1	295	9.0e-100	356	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
644988604	457	53.57	173	452	1	261	1.0e-88	320	COG1760	L-serine deaminase	262
644988606	472	38.43	29	471	22	456	4.0e-126	444	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
644988607	501	49.84	1	302	2	297	4.0e-106	378	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
644988608	294	56.29	2	287	5	289	7.0e-100	357	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
644988609	379	46.37	1	379	8	390	2.0e-121	428	COG0372	Citrate synthase	390
644988610	863	50.06	1	860	1	861	0.0e+00	1081	COG1048	Aconitase A	861
644988612	394	63.17	6	394	1	378	0.0e+00	514	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
644988615	347	30.18	29	300	44	309	4.0e-39	155	COG4257	Streptogramin lyase	353
644988618	832	22.82	85	600	60	448	9.0e-36	146	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
644988619	427	22.9	27	406	4	383	4.0e-54	205	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644988620	481	42.58	8	478	1	452	5.0e-127	448	COG2079	2-methylcitrate dehydratase PrpD	453
644988622	388	30.55	48	387	9	311	7.0e-48	185	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
644988623	89	27.06	1	77	36	120	3.0e-07	46.9	COG1734	RNA polymerase-binding transcription factor DksA	120
644988624	305	27.02	23	300	17	286	1.0e-36	147	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644988627	251	22.33	3	215	7	205	4.0e-19	88.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644988628	166	22.52	1	144	9	154	4.0e-08	51.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
644988630	142	38.73	3	141	22	162	1.0e-29	122	COG4067	Uncharacterized conserved protein	162
644988631	304	33.44	1	291	1	313	1.0e-57	217	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
644988633	773	40.53	1	523	1	509	5.0e-122	432	COG2812	DNA polymerase III, gamma/tau subunits	515
644988634	109	54.72	1	105	1	104	3.0e-23	100	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
644988635	199	55.33	1	197	2	198	7.0e-76	276	COG0353	Recombinational DNA repair protein RecR	198
644988636	210	36.57	1	209	5	217	3.0e-40	158	COG4122	Predicted O-methyltransferase YrrM	219
644988637	536	23.92	73	411	22	325	1.0e-16	81.6	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
644988639	634	59.62	5	632	2	621	0.0e+00	804	COG0326	Molecular chaperone, HSP90 family	623
644988648	218	40.72	1	217	1	178	1.0e-44	173	COG0563	Adenylate kinase or related kinase	178
644988649	330	45.92	1	330	3	320	9.0e-101	360	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
644988650	653	37.04	11	648	1	648	1.0e-129	457	COG1199	Rad3-related DNA helicase	654
644988651	235	39.74	2	227	1	218	1.0e-42	166	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
644988652	241	31.64	1	173	5	179	4.0e-31	128	COG3065	Starvation-inducible outer membrane lipoprotein	191
644988653	467	31.78	18	466	10	455	2.0e-61	230	COG0534	Na+-driven multidrug efflux pump	455
644988654	390	38.33	4	347	11	344	4.0e-68	252	COG2850	Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain	383
644988655	454	33.19	12	454	1	435	8.0e-114	404	COG0015	Adenylosuccinate lyase	438
644988658	870	77.33	1	858	1	850	0.0e+00	1454	COG1049	Aconitase B	852
644988659	132	42.4	5	129	6	128	8.0e-20	89.2	COG3788	Uncharacterized membrane protein YecN, MAPEG domain	131
644988660	861	17.56	1	267	2	275	2.0e-15	78.5	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644988662	218	62.21	3	218	6	222	4.0e-80	290	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
644988663	238	56.28	5	219	2	216	8.0e-78	283	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
644988665	669	52.77	1	666	1	644	0.0e+00	825	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
644988666	284	36.59	28	272	14	256	2.0e-47	182	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
644988667	536	45.44	12	536	1	526	0.0e+00	653	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
644988668	382	48.84	1	379	3	386	1.0e-103	370	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644988669	392	42.64	2	389	1	388	2.0e-82	299	COG0183	Acetyl-CoA acetyltransferase	392
644988670	386	44.7	5	382	1	387	6.0e-101	361	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644988671	127	33.91	14	126	1	113	5.0e-11	60.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
644988672	60	59.18	1	49	1	49	5.0e-12	62.7	COG3130	Ribosome modulation factor	55
644988674	1645	30.23	46	1637	53	1617	0.0e+00	797	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
644988675	787	42.02	19	786	6	732	0.0e+00	674	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
644988676	365	57.06	1	342	1	347	0.0e+00	498	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
644988677	373	61.19	3	373	1	371	0.0e+00	557	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
644988678	104	47.92	6	101	1	96	1.0e-24	104	COG1862	Preprotein translocase subunit YajC	97
644988679	639	47.15	117	639	16	506	3.0e-122	432	COG0342	Preprotein translocase subunit SecD	506
644988680	312	48.85	1	305	1	304	1.0e-85	309	COG0341	Preprotein translocase subunit SecF	305
644988681	384	30.33	85	382	7	303	9.0e-33	134	COG0668	Small-conductance mechanosensitive channel	316
644988683	455	39.37	19	453	4	435	0.0e+00	468	COG0621	tRNA A37 methylthiotransferase MiaB	437
644988684	460	31.22	142	344	4	201	1.0e-42	167	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
644988685	180	22.94	7	165	9	166	1.0e-11	62.7	COG4970	Tfp pilus assembly protein FimT	181
644988686	442	32.53	4	442	3	457	7.0e-93	334	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644988688	539	44.8	257	526	4	268	4.0e-74	272	COG0171	NH3-dependent NAD+ synthetase	268
644988689	112	75.89	1	112	1	112	3.0e-40	156	COG0347	Nitrogen regulatory protein PII	112
644988690	268	39.75	19	262	3	236	1.0e-52	199	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
644988691	324	46.69	8	304	2	289	1.0e-76	280	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644988692	241	50.2	4	241	3	249	3.0e-72	265	COG1496	Copper oxidase (laccase) domain	249
644988693	248	26.98	6	190	2	190	1.0e-15	76.9	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
644988694	862	56.4	5	862	1	783	0.0e+00	973	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
644988695	399	38.15	1	398	1	396	2.0e-66	246	COG3213	Uncharacterized protein involved in response to NO	396
644988701	266	39.73	11	232	6	225	3.0e-49	188	COG1183	Phosphatidylserine synthase	234
644988707	188	25.27	8	181	2	182	2.0e-23	102	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644988710	204	38.42	5	204	3	205	1.0e-43	169	COG2915	Regulator of phage lambda lysogenization HflD, binds to CII and stimulates its degradation	207
644988711	367	61.88	6	365	1	355	0.0e+00	505	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
644988712	167	28.7	5	119	10	124	7.0e-14	70.4	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
644988714	740	74.53	3	740	5	742	0.0e+00	1236	COG2838	Monomeric isocitrate dehydrogenase	744
644988719	422	25.77	9	356	4	347	4.0e-46	179	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
644988722	335	43.44	1	335	1	342	1.0e-92	333	COG2008	Threonine aldolase	342
644988723	202	25.25	1	196	2	198	5.0e-07	47.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644988724	378	34.63	10	289	17	289	3.0e-60	225	COG1398	Fatty-acid desaturase	289
644988725	315	50.48	5	315	2	302	2.0e-95	342	COG0492	Thioredoxin reductase	305
644988728	68	64.18	3	68	1	67	7.0e-22	95.6	COG1278	Cold shock protein, CspA family	67
644988731	377	65.95	1	370	1	370	0.0e+00	529	COG0686	Alanine dehydrogenase	371
644988732	165	48.7	7	160	2	154	8.0e-37	146	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644988734	227	28.5	3	214	1	211	2.0e-27	116	COG2834	Outer membrane lipoprotein-sorting protein	211
644988735	451	58.35	8	444	5	436	0.0e+00	611	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
644988736	127	40.48	2	126	1	126	5.0e-18	83.3	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
644988737	422	61.27	1	422	1	420	0.0e+00	574	COG0172	Seryl-tRNA synthetase	429
644988739	226	34.07	126	215	2	92	6.0e-13	67.6	COG0607	Rhodanese-related sulfurtransferase	110
644988740	127	28.97	17	123	19	124	1.0e-08	52.2	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
644988741	285	31.58	2	282	1	272	9.0e-53	200	COG0388	Predicted amidohydrolase	274
644988742	327	40.42	3	325	12	344	8.0e-86	310	COG2957	Agmatine/peptidylarginine deiminase	346
644988743	644	53.67	4	644	20	651	0.0e+00	796	COG1166	Arginine decarboxylase (spermidine biosynthesis)	652
644988744	287	47.22	1	287	1	281	2.0e-85	308	COG0421	Spermidine synthase	282
644988745	157	38.94	47	156	15	126	2.0e-28	118	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
644988746	290	20.38	31	279	38	282	1.0e-05	44.1	COG5006	Threonine/homoserine efflux transporter RhtA	292
644988748	345	32.22	1	345	27	407	4.0e-82	298	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
644988749	506	35.96	28	494	13	472	8.0e-107	381	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644988752	380	33.24	1	351	1	360	1.0e-66	247	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
644988754	1140	52.21	18	1140	14	1134	0.0e+00	1361	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
644988757	657	34.55	430	620	1	180	2.0e-34	141	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644988758	623	29.36	5	403	7	419	5.0e-53	202	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
644988759	405	33.67	55	344	50	343	1.0e-54	207	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
644988761	119	48.48	4	69	2	67	4.0e-16	76.6	COG3139	Uncharacterized conserved protein YeaC, DUF1315 family	90
644988764	339	35.1	1	333	17	351	4.0e-76	278	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
644988769	730	16.06	11	730	31	768	2.0e-29	125	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644988771	203	23.2	19	195	30	210	2.0e-13	69.1	COG3201	Nicotinamide riboside transporter PnuC	222
644988773	444	43.49	37	440	6	392	1.0e-112	400	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
644988774	806	28.79	120	507	5	382	1.0e-50	195	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644988776	1311	35.22	52	980	7	845	0.0e+00	671	COG1643	HrpA-like RNA helicase	845
644988777	426	27.54	54	416	63	432	8.0e-56	211	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
644988779	267	44.98	6	254	6	242	2.0e-56	212	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
644988780	1165	35.5	1	1163	1	1163	0.0e+00	593	COG1196	Chromosome segregation ATPase	1163
644988781	322	28.57	7	318	6	324	2.0e-40	159	COG3115	Cell division protein ZipA, interacts with FtsZ	324
644988782	667	59.22	1	667	4	665	0.0e+00	923	COG0272	NAD-dependent DNA ligase	667
644988784	951	52.13	1	491	1	487	0.0e+00	533	COG1530	Ribonuclease G or E	487
644988785	316	41	9	304	1	288	1.0e-71	263	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644988786	213	34.91	4	210	2	213	2.0e-39	156	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
644988789	417	32.79	7	413	10	431	1.0e-50	193	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
644988791	178	50.33	27	173	6	156	3.0e-46	178	COG1225	Peroxiredoxin	157
644988792	184	33.55	10	155	1	152	3.0e-22	98.1	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644988793	172	52.25	1	172	3	174	7.0e-46	176	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
644988794	251	38	2	246	43	283	9.0e-50	190	COG3001	Fructosamine-3-kinase	286
644988797	194	47.09	4	191	3	189	7.0e-56	210	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
644988798	174	31.51	31	172	31	174	2.0e-13	69.2	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
644988799	54	52.73	1	54	1	55	3.0e-10	56.8	COG0333	Ribosomal protein L32	57
644988800	345	48.66	3	339	2	334	9.0e-115	406	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
644988801	320	56.21	1	320	1	322	2.0e-121	429	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
644988802	309	56.13	1	309	1	310	2.0e-101	362	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
644988803	248	48.03	1	245	1	250	1.0e-53	203	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644988804	79	69.74	1	76	3	78	3.0e-11	60.3	COG0236	Acyl carrier protein	80
644988805	412	55.21	2	412	1	411	0.0e+00	502	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644988806	281	23.4	14	281	5	283	1.0e-28	120	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
644988807	334	37.65	2	333	9	339	1.0e-90	326	COG1559	Cell division protein YceG, involved in septum cleavage	342
644988808	216	48.76	6	205	2	201	2.0e-60	225	COG0125	Thymidylate kinase	208
644988810	116	57.14	6	116	7	117	5.0e-37	146	COG3215	Tfp pilus assembly protein PilZ	117
644988811	264	52.69	1	258	2	256	3.0e-81	295	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
644988812	950	26.39	506	930	6	436	2.0e-57	218	COG0612	Predicted Zn-dependent peptidase	438
644988817	1121	28.93	38	293	2	277	6.0e-32	133	COG0515	Serine/threonine protein kinase	384
644988819	212	41.9	2	211	1	209	3.0e-51	194	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644988821	826	23.33	93	533	90	489	1.0e-15	78.9	COG1404	Serine protease, subtilisin family	508
644988822	392	38.01	15	391	1	392	1.0e-79	290	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644988824	727	37.44	152	579	10	387	2.0e-81	297	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
644988826	323	27.61	27	322	25	321	3.0e-48	185	COG0598	Mg2+ and Co2+ transporter CorA	322
644988829	128	47.66	7	113	17	123	2.0e-27	114	COG4273	Uncharacterized protein, contains metal-binding DGC domain	135
644988830	679	28.89	10	667	1	667	0.0e+00	608	COG1328	Anaerobic ribonucleoside-triphosphate reductase	700
644988832	249	28.95	15	198	17	204	1.0e-29	123	COG1180	Pyruvate-formate lyase-activating enzyme	260
644988833	240	25.47	13	221	1	211	1.0e-27	116	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
644988835	438	42.82	1	380	4	346	3.0e-109	388	COG0826	Collagenase-like protease, PrtC family	347
644988836	274	49.24	1	261	26	288	3.0e-86	311	COG3186	Phenylalanine-4-hydroxylase	291
644988837	181	25.18	5	136	2	138	5.0e-11	61	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644988838	356	44.44	11	356	15	359	4.0e-88	318	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
644988839	247	44.44	1	246	2	253	2.0e-63	236	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
644988841	304	40.14	18	290	5	276	2.0e-63	236	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
644988842	251	41.73	1	249	1	251	5.0e-55	207	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644988845	126	28.23	7	124	9	127	1.0e-06	45.7	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
644988846	441	25.68	4	433	11	442	7.0e-18	85.6	COG0531	Amino acid transporter	466
644988847	269	22.89	8	267	5	283	2.0e-29	123	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
644988848	441	28.52	217	441	71	313	6.0e-26	112	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
644988849	313	39.74	12	307	19	317	5.0e-72	264	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
644988851	144	46.38	8	144	18	155	5.0e-22	96.9	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
644988852	468	21.46	23	453	7	404	3.0e-33	136	COG1228	Imidazolonepropionase or related amidohydrolase	406
644988853	147	41.18	13	146	11	141	3.0e-13	67.7	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
644988854	302	34.11	4	299	3	297	5.0e-46	178	COG0583	DNA-binding transcriptional regulator, LysR family	297
644988855	479	22.48	160	472	35	380	7.0e-32	132	COG1680	CubicO group peptidase, beta-lactamase class C family	390
644988857	175	31.36	9	170	4	172	5.0e-24	104	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644988859	91	31.33	1	83	4	84	1.0e-11	61.5	COG3630	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit	84
644988860	601	61.73	1	471	1	466	0.0e+00	707	COG5016	Pyruvate/oxaloacetate carboxyltransferase	472
644988861	432	62.96	1	432	1	375	0.0e+00	472	COG1883	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit	375
644988863	370	29.03	278	370	34	125	3.0e-13	69.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644988864	207	32.52	3	207	2	206	2.0e-26	112	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644988874	313	19.35	20	313	24	294	6.0e-08	52.1	COG4974	Site-specific recombinase XerD	300
644988877	410	21.82	53	398	85	445	4.0e-12	65.9	COG1538	Outer membrane protein TolC	457
644988878	436	25.91	108	419	33	356	5.0e-18	85.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644988879	1064	45.48	1	1062	1	1025	0.0e+00	1045	COG3696	Cu/Ag efflux pump CusA	1027
644988880	135	36.36	1	109	1	110	2.0e-19	87.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
644988882	295	36.59	1	282	8	292	8.0e-61	227	COG1230	Co/Zn/Cd efflux system component	296
644988883	545	36.28	85	530	7	454	6.0e-108	385	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
644988884	91	41.43	22	91	2	71	1.0e-08	51.5	COG2608	Copper chaperone CopZ	71
644988886	130	39.47	2	111	1	114	1.0e-16	78.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
644988887	125	26.61	1	124	2	123	3.0e-15	73.8	COG3682	Predicted transcriptional regulator	123
644988889	440	16.92	53	433	44	444	5.0e-23	102	COG1538	Outer membrane protein TolC	457
644988891	1042	47.97	1	1032	1	1021	0.0e+00	1154	COG3696	Cu/Ag efflux pump CusA	1027
644988895	351	27.01	9	141	18	151	5.0e-10	59.1	COG4244	Uncharacterized membrane protein	160
644988901	193	35	9	188	12	167	5.0e-30	124	COG0723	Rieske Fe-S protein	177
644988902	422	30.83	1	411	5	391	6.0e-36	145	COG0475	Kef-type K+ transport system, membrane component KefB	397
644988903	450	34.37	131	449	18	330	1.0e-38	154	COG0642	Signal transduction histidine kinase	336
644988904	230	44.54	1	224	1	228	1.0e-59	222	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644988907	591	26.79	9	423	1	363	4.0e-57	216	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
644988909	443	31.42	1	357	2	365	1.0e-18	88.3	COG0531	Amino acid transporter	466
644988911	180	44.8	42	166	28	149	1.0e-34	139	COG3019	Uncharacterized conserved protein	149
644988912	440	19.16	26	423	41	438	3.0e-17	83.3	COG1538	Outer membrane protein TolC	457
644988913	539	29.65	95	380	41	353	1.0e-25	111	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644988914	1040	50.14	1	1040	1	1025	0.0e+00	1217	COG3696	Cu/Ag efflux pump CusA	1027
644988915	142	23.28	1	115	1	116	1.0e-13	68.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
644988916	766	46.29	26	761	3	710	0.0e+00	730	COG2217	Cation transport ATPase	713
644988920	213	24.49	14	208	1	185	7.0e-17	80.9	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
644988922	510	31.26	102	502	4	419	3.0e-90	326	COG0213	Thymidine phosphorylase	435
644988923	303	28.88	8	278	6	279	2.0e-51	196	COG0462	Phosphoribosylpyrophosphate synthetase	314
644988924	451	36.61	1	435	1	409	4.0e-82	298	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
644988927	375	31.84	8	368	5	391	1.0e-70	260	COG0282	Acetate kinase	396
644988928	788	22.31	71	784	29	754	2.0e-109	390	COG3957	Phosphoketolase	793
644988929	377	33.77	21	377	57	438	1.0e-56	214	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
644988934	99	33.33	24	86	5	66	2.0e-07	47.3	COG2608	Copper chaperone CopZ	71
644988940	162	55.77	1	156	3	157	2.0e-56	211	COG0315	Molybdenum cofactor biosynthesis enzyme	157
644988941	81	38.1	1	81	1	84	3.0e-14	70	COG1977	Molybdopterin converting factor, small subunit	84
644988942	164	47.22	3	146	6	144	2.0e-40	158	COG0314	Molybdopterin synthase catalytic subunit	149
644988943	199	32.64	8	199	5	189	7.0e-35	140	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
644988944	360	38.5	3	360	1	352	5.0e-76	278	COG4148	ABC-type molybdate transport system, ATPase component	352
644988945	226	43.12	6	223	4	221	2.0e-57	215	COG4149	ABC-type molybdate transport system, permease component	225
644988946	239	27.8	4	234	15	255	3.0e-28	118	COG0725	ABC-type molybdate transport system, periplasmic component	258
644988947	332	44.04	7	332	2	322	4.0e-99	354	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
644988949	225	48	3	225	1	224	3.0e-58	218	COG2181	Nitrate reductase gamma subunit	228
644988950	243	40.22	1	179	4	178	7.0e-36	144	COG2180	Nitrate reductase assembly protein NarJ, required for insertion of molybdenum cofactor	179
644988951	518	74.41	1	512	1	510	0.0e+00	927	COG1140	Nitrate reductase beta subunit	513
644988952	1250	73.1	1	1233	1	1227	0.0e+00	2125	COG5013	Nitrate reductase alpha subunit	1227
644988954	415	37.59	5	413	9	409	2.0e-92	332	COG2223	Nitrate/nitrite transporter NarK	417
644988955	584	34.89	1	578	13	571	2.0e-112	400	COG3850	Signal transduction histidine kinase, nitrate/nitrite-specific	574
644988956	214	43.75	6	213	1	208	3.0e-52	198	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644988957	408	40.05	4	408	1	402	9.0e-112	397	COG0303	Molybdopterin biosynthesis enzyme	404
644988958	189	48.17	10	171	4	166	2.0e-50	192	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
644988959	247	46.43	1	246	2	253	4.0e-67	248	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
644988960	467	21.43	36	463	3	419	2.0e-36	146	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
644988962	535	47.9	34	529	7	500	0.0e+00	494	COG1292	Choline-glycine betaine transporter	537
644988965	750	45.84	8	748	1	713	0.0e+00	758	COG2217	Cation transport ATPase	713
644988967	126	41.32	2	114	1	121	6.0e-16	76.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
644988968	113	41.67	1	84	13	96	3.0e-11	60.6	COG0640	DNA-binding transcriptional regulator, ArsR family	110
644988969	157	36.17	1	136	3	137	1.0e-26	112	COG0394	Protein-tyrosine-phosphatase	139
644988970	339	48.22	1	337	9	336	2.0e-84	306	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
644988972	248	35.66	3	248	10	257	2.0e-37	149	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
644988973	504	34.77	97	494	3	416	4.0e-97	349	COG0213	Thymidine phosphorylase	435
644988974	294	28.81	6	289	8	299	3.0e-51	195	COG0462	Phosphoribosylpyrophosphate synthetase	314
644988975	531	26.81	5	404	7	410	7.0e-47	182	COG1283	Na+/phosphate symporter	533
644988976	462	33.18	1	431	1	394	7.0e-75	274	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
644988978	477	43.74	9	477	2	468	0.0e+00	507	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644988979	588	33.5	1	588	3	577	4.0e-130	458	COG0018	Arginyl-tRNA synthetase	577
644988980	162	43.59	2	157	1	139	2.0e-35	141	COG0394	Protein-tyrosine-phosphatase	139
644988981	256	59.52	5	256	3	247	2.0e-93	335	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
644988982	61	59.65	1	57	1	57	9.0e-16	75.3	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
644988983	321	45.69	9	300	4	313	1.0e-86	313	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
644988984	582	39.44	10	582	1	567	0.0e+00	474	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
644988985	140	32.59	3	136	7	137	3.0e-23	101	COG0848	Biopolymer transport protein ExbD	137
644988986	217	28.1	1	209	2	211	7.0e-30	123	COG0811	Biopolymer transport protein ExbB/TolQ	216
644988990	780	30.19	479	773	4	293	8.0e-53	202	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
644988991	213	26.82	1	176	4	182	2.0e-38	152	COG3216	Uncharacterized conserved protein, DUF2062 family	184
644988992	228	52.68	6	228	1	224	2.0e-74	272	COG1136	ABC-type lipoprotein export system, ATPase component	226
644988993	414	45.93	1	414	1	408	2.0e-101	362	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
644988995	119	26.37	27	116	3	93	2.0e-09	54.3	COG5626	Uncharacterized protein	97
644988996	336	40.3	4	326	6	328	3.0e-70	258	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
644988998	486	41.95	308	480	6	177	9.0e-41	161	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644988999	231	46.89	25	231	16	224	1.0e-49	189	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
644989002	673	42.15	1	355	1	362	6.0e-108	385	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
644989003	619	36.75	267	568	6	303	1.0e-60	228	COG0616	Periplasmic serine protease, ClpP class	317
644989005	150	49.66	1	145	6	148	2.0e-38	151	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
644989006	88	44.32	1	88	11	98	9.0e-20	88.5	COG3100	Uncharacterized conserved protein YcgL, UPF0745 family	103
644989007	384	35.56	18	345	1	329	4.0e-67	249	COG0349	Ribonuclease D	361
644989008	552	37.96	15	552	3	523	0.0e+00	477	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644989009	288	21.94	15	284	9	281	6.0e-19	88.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644989010	288	23.79	45	270	26	223	5.0e-09	55.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644989012	486	32.98	14	476	23	466	1.0e-65	244	COG1757	Na+/H+ antiporter NhaC	485
644989013	434	21.67	21	406	1	398	8.0e-16	78.9	COG1228	Imidazolonepropionase or related amidohydrolase	406
644989014	475	28.5	54	447	13	403	4.0e-56	212	COG1228	Imidazolonepropionase or related amidohydrolase	406
644989015	466	42.09	1	461	1	439	2.0e-93	336	COG0733	Na+-dependent transporter, SNF family	439
644989017	565	32.7	36	450	7	387	2.0e-68	253	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644989018	561	49.85	5	333	2	329	4.0e-109	389	COG1115	Na+/alanine symporter	452
644989019	369	45.64	12	344	1	341	3.0e-90	325	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
644989021	453	23.96	150	451	15	327	2.0e-31	130	COG0642	Signal transduction histidine kinase	336
644989022	224	42.79	1	223	1	228	3.0e-55	208	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644989024	183	34.53	47	174	35	170	6.0e-14	70.8	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
644989025	83	49.4	1	83	1	82	1.0e-05	41.6	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
644989026	546	33.83	7	541	16	611	2.0e-117	416	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
644989027	152	22.83	27	147	33	148	1.0e-05	42.6	COG2153	Predicted N-acyltransferase, GNAT family	155
644989029	789	49.36	1	786	1	734	0.0e+00	737	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
644989030	273	41.94	1	273	2	273	2.0e-74	272	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
644989031	342	36.93	37	341	28	323	2.0e-68	252	COG2988	Succinylglutamate desuccinylase	324
644989032	288	25.63	54	287	41	277	8.0e-26	111	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
644989033	501	27.79	84	481	29	416	4.0e-47	182	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
644989037	448	28.24	6	263	17	274	2.0e-41	163	COG3452	Extracellular (periplasmic) sensor domain CHASE (specificity unknown)	297
644989038	400	20	1	333	9	350	1.0e-13	71.1	COG1566	Multidrug resistance efflux pump	352
644989039	788	20.68	421	785	9	406	4.0e-18	87.2	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
644989040	252	43.81	22	241	1	226	1.0e-70	259	COG1136	ABC-type lipoprotein export system, ATPase component	226
644989044	70	41.18	1	68	2	69	5.0e-13	66	COG2501	Ribosome-associated protein YbcJ, S4-like RNA binding protein	73
644989048	71	63.08	1	65	1	65	6.0e-20	89.2	COG1551	sRNA-binding carbon storage regulator CsrA	73
644989049	875	57.26	1	874	6	879	0.0e+00	1169	COG0013	Alanyl-tRNA synthetase	879
644989050	156	40	14	156	26	170	4.0e-24	104	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
644989051	346	64.91	1	282	3	279	3.0e-89	322	COG0468	RecA/RadA recombinase	279
644989052	173	44.08	15	166	8	157	5.0e-44	170	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
644989053	864	47.27	13	861	3	843	0.0e+00	891	COG0249	DNA mismatch repair ATPase MutS	843
644989054	107	41.54	4	64	5	67	9.0e-08	48.6	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
644989055	704	19.2	293	666	18	380	5.0e-16	80.2	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
644989059	424	22.3	1	402	3	387	8.0e-30	125	COG1252	NADH dehydrogenase, FAD-containing subunit	405
644989060	400	49.74	9	394	8	394	0.0e+00	481	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
644989061	162	42.76	8	159	4	154	5.0e-34	137	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644989063	703	24.77	44	678	2	619	6.0e-71	262	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
644989064	103	35.56	9	96	3	92	2.0e-09	53.8	COG1605	Chorismate mutase	101
644989067	222	40.55	11	222	75	289	1.0e-50	192	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644989070	187	29.19	3	181	2	182	7.0e-21	93.8	COG3150	Predicted esterase YcpF, UPF0227 family	191
644989071	338	21.86	6	335	4	310	7.0e-18	85.1	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
644989073	241	49.11	14	237	3	221	2.0e-78	286	COG2360	Leu/Phe-tRNA-protein transferase	221
644989074	252	41.53	3	244	2	249	5.0e-67	247	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
644989075	72	70.83	1	72	1	72	2.0e-25	107	COG0361	Translation initiation factor IF-1	75
644989076	755	47.75	1	745	1	785	0.0e+00	854	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
644989077	115	60.23	25	112	20	107	6.0e-31	125	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
644989079	178	32.52	16	176	2	161	3.0e-29	121	COG2062	Phosphohistidine phosphatase SixA	163
644989080	174	43.1	1	174	1	169	1.0e-33	136	COG2862	Uncharacterized membrane protein YqhA	169
644989081	110	50.85	1	59	1	59	2.0e-12	64.6	COG3422	Uncharacterized conserved protein YegP, UPF0339 family	59
644989082	197	28.14	13	175	11	177	4.0e-11	61.4	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
644989083	185	56.55	14	181	2	167	7.0e-66	243	COG0225	Peptide methionine sulfoxide reductase MsrA	174
644989087	472	45.28	2	464	9	472	0.0e+00	499	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
644989089	463	37.66	9	462	1	456	1.0e-93	337	COG0277	FAD/FMN-containing dehydrogenase	459
644989091	1127	24.61	891	1081	2	178	2.0e-20	95.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644989093	506	52.05	1	483	4	470	0.0e+00	604	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
644989094	174	40.26	1	154	1	154	3.0e-28	118	COG1286	Uncharacterized membrane protein, required for colicin V production	182
644989095	255	26.95	1	250	1	225	6.0e-17	81.2	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
644989096	436	37.38	5	425	2	423	7.0e-98	351	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
644989097	288	61.81	1	287	1	288	2.0e-115	408	COG0777	Acetyl-CoA carboxylase beta subunit	294
644989098	264	50	1	264	1	264	1.0e-89	322	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
644989099	767	24.72	3	766	15	753	1.0e-55	212	COG3170	Tfp pilus assembly protein FimV	755
644989100	339	55.92	3	335	1	334	2.0e-115	409	COG0136	Aspartate-semialdehyde dehydrogenase	334
644989102	888	36.02	1	882	3	859	0.0e+00	614	COG0308	Aminopeptidase N	859
644989104	363	41.19	15	352	5	356	2.0e-97	349	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
644989105	326	58.2	4	325	2	324	2.0e-130	458	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
644989106	572	32.75	238	568	56	395	2.0e-53	204	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
644989108	692	43.88	25	692	4	648	0.0e+00	679	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
644989109	278	37.08	5	267	2	267	4.0e-70	258	COG0263	Glutamate 5-kinase	369
644989110	267	39.47	6	267	2	267	5.0e-75	274	COG0263	Glutamate 5-kinase	369
644989111	428	48.79	14	424	3	414	0.0e+00	510	COG0014	Gamma-glutamyl phosphate reductase	417
644989115	64	65.62	1	64	1	64	3.0e-20	90	COG2975	Fe-S-cluster formation regulator IscX/YfhJ	64
644989116	112	46.23	1	104	1	102	5.0e-19	86.3	COG0633	Ferredoxin	102
644989117	617	44.31	18	603	4	579	0.0e+00	506	COG0443	Molecular chaperone DnaK (HSP70)	579
644989118	177	30.23	6	175	1	170	5.0e-16	77.7	COG1076	DnaJ-domain-containing proteins 1	174
644989119	107	61.11	1	107	3	110	8.0e-36	141	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
644989120	127	53.1	1	126	5	146	6.0e-38	149	COG0822	NifU homolog involved in Fe-S cluster formation	150
644989121	404	59.85	3	388	1	386	0.0e+00	556	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
644989122	155	40.69	1	144	1	145	3.0e-38	151	COG1959	DNA-binding transcriptional regulator, IscR family	150
644989123	284	56.25	1	192	3	193	7.0e-71	260	COG1045	Serine acetyltransferase	194
644989124	277	46.39	15	277	1	241	8.0e-75	274	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
644989125	258	46.54	1	256	1	260	6.0e-70	257	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
644989127	309	55.24	1	309	1	310	2.0e-92	332	COG2025	Electron transfer flavoprotein, alpha subunit	313
644989128	249	49.23	1	249	1	260	6.0e-69	254	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
644989129	546	32.9	1	458	2	396	8.0e-73	268	COG0644	Dehydrogenase (flavoprotein)	396
644989131	215	31.19	2	215	1	210	4.0e-31	128	COG0625	Glutathione S-transferase	211
644989132	329	23.46	4	326	1	266	4.0e-37	148	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
644989133	376	23.1	1	375	7	421	2.0e-88	319	COG3508	Homogentisate 1,2-dioxygenase	427
644989134	353	56.62	3	353	12	359	1.0e-126	446	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
644989135	267	53.26	5	262	27	287	4.0e-95	341	COG3186	Phenylalanine-4-hydroxylase	291
644989136	646	25	346	628	3	288	3.0e-26	113	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
644989139	221	62.96	6	220	5	220	4.0e-94	337	COG0692	Uracil DNA glycosylase	223
644989142	469	22.77	14	455	11	421	4.0e-52	199	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
644989143	409	39.36	10	408	4	395	1.0e-99	357	COG1228	Imidazolonepropionase or related amidohydrolase	406
644989144	141	38.36	1	138	3	147	1.0e-26	112	COG3241	Azurin	151
644989145	401	37.34	141	372	5	237	3.0e-59	222	COG3741	N-formylglutamate amidohydrolase	272
644989146	243	30.93	1	234	1	236	8.0e-51	193	COG2188	DNA-binding transcriptional regulator, GntR family	236
644989147	561	74.95	5	559	4	558	0.0e+00	985	COG2987	Urocanate hydratase	561
644989148	510	57.31	1	499	1	498	0.0e+00	646	COG2986	Histidine ammonia-lyase	498
644989150	190	29.48	5	170	1	173	2.0e-23	101	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
644989151	519	26.96	67	519	6	421	9.0e-59	221	COG5316	Uncharacterized protein	421
644989152	914	30.02	37	447	16	433	7.0e-60	226	COG0612	Predicted Zn-dependent peptidase	438
644989153	290	72.16	1	290	1	291	2.0e-122	431	COG0074	Succinyl-CoA synthetase, alpha subunit	293
644989154	388	65.64	1	388	1	387	0.0e+00	551	COG0045	Succinyl-CoA synthetase, beta subunit	387
644989155	416	50	1	415	1	404	3.0e-113	402	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
644989156	939	58.72	5	938	1	906	0.0e+00	1294	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
644989157	232	58.97	1	232	3	232	3.0e-85	308	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
644989158	592	51.38	8	577	2	561	0.0e+00	625	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
644989159	117	35.65	3	117	2	116	1.0e-16	78.7	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
644989160	125	34.65	4	125	2	128	1.0e-11	62.2	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
644989161	429	55.09	28	429	2	390	0.0e+00	493	COG0372	Citrate synthase	390
644989162	359	28.87	5	340	1	262	5.0e-42	165	COG3483	Tryptophan 2,3-dioxygenase (vermilion)	262
644989163	141	54.61	1	141	1	138	4.0e-45	173	COG3565	Predicted dioxygenase of extradiol dioxygenase family	138
644989164	171	53.99	7	169	3	162	2.0e-54	205	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
644989165	65	46.43	10	65	4	58	3.0e-10	56.9	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
644989166	465	45.73	1	465	3	435	0.0e+00	537	COG0017	Aspartyl/asparaginyl-tRNA synthetase	435
644989168	183	24.38	1	183	5	205	2.0e-14	72.3	COG0778	Nitroreductase	207
644989174	686	24.4	25	686	1	620	2.0e-96	347	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
644989175	405	22.72	1	378	1	366	9.0e-17	81.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644989176	1061	24.74	10	1036	1	1006	0.0e+00	554	COG0841	Multidrug efflux pump subunit AcrB	1009
644989177	481	48.43	1	477	3	477	0.0e+00	540	COG0469	Pyruvate kinase	477
644989178	298	26.12	7	139	5	137	3.0e-06	46	COG2510	Uncharacterized membrane protein	140
644989179	353	33.33	1	151	8	158	1.0e-18	87.5	COG2030	Acyl dehydratase	159
644989180	301	32.62	12	287	1	277	1.0e-55	210	COG2301	Citrate lyase beta subunit	283
644989181	550	27.98	19	541	1	516	3.0e-104	373	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
644989182	373	26.64	46	346	8	283	8.0e-23	101	COG2301	Citrate lyase beta subunit	283
644989183	330	25.17	28	321	7	283	4.0e-30	125	COG2301	Citrate lyase beta subunit	283
644989184	587	36.94	21	583	14	567	1.0e-114	407	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
644989192	243	21.94	1	236	1	228	5.0e-33	134	COG1018	Ferredoxin-NADP reductase	266
644989194	130	46.46	3	129	2	126	7.0e-30	122	COG1553	Sulfur relay (sulfurtransferase) complex TusBCD TusD component, DsrE family	126
644989195	122	39.5	4	122	2	118	2.0e-21	94.5	COG2923	Sulfur relay (sulfurtransferase) complex TusC component, DsrF/TusC family	118
644989196	91	35.44	17	90	19	96	2.0e-09	54.5	COG2168	Sulfur transfer complex TusBCD TusB component, DsrH family	96
644989197	108	66.33	11	108	14	111	2.0e-37	147	COG2920	Sulfur relay (sulfurtransferase) protein, DsrC/TusE family	111
644989198	218	30.85	1	200	3	202	5.0e-30	124	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
644989199	157	50.61	1	157	2	165	4.0e-52	197	COG0678	Peroxiredoxin	165
644989200	580	41.39	42	580	11	539	0.0e+00	564	COG0405	Gamma-glutamyltranspeptidase	539
644989201	59	45.16	1	59	2	63	1.0e-10	57.9	COG1983	Phage shock protein PspC (stress-responsive transcriptional regulator)	70
644989202	398	39.86	103	382	1	278	4.0e-76	278	COG0077	Prephenate dehydratase	279
644989203	353	57.85	12	352	3	346	0.0e+00	508	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
644989205	324	52.82	2	301	7	307	9.0e-118	416	COG1054	Predicted sulfurtransferase	308
644989207	226	31.08	4	225	10	221	6.0e-36	144	COG1451	Predicted metal-dependent hydrolase	223
644989208	97	50.6	1	83	3	83	1.0e-20	91.5	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
644989210	331	29.94	6	328	4	330	4.0e-50	192	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
644989211	229	33.64	5	209	2	209	2.0e-29	122	COG2928	Uncharacterized membrane protein	222
644989212	399	44.88	16	393	6	384	8.0e-109	387	COG3146	Predicted N-acyltransferase	387
644989213	735	44.93	55	733	2	681	0.0e+00	767	COG0339	Zn-dependent oligopeptidase	683
644989217	189	31.37	91	189	12	112	3.0e-18	85	COG2824	Uncharacterized Zn-ribbon-containing protein	112
644989218	348	19.29	2	344	4	386	6.0e-17	81.9	COG3182	Uncharacterized iron-regulated membrane protein	442
644989219	709	16.38	1	709	14	768	4.0e-31	130	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644989222	182	45.36	2	182	1	180	3.0e-50	191	COG2096	Cob(I)alamin adenosyltransferase	184
644989223	654	22.29	32	649	19	603	1.0e-42	168	COG4206	Outer membrane cobalamin receptor protein	608
644989224	1227	55.47	326	1193	2	842	0.0e+00	1146	COG1410	Methionine synthase I, cobalamin-binding domain	842
644989226	454	18.72	16	443	18	438	2.0e-17	84.4	COG1538	Outer membrane protein TolC	457
644989227	538	26.69	87	381	32	353	2.0e-26	114	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644989228	1043	49.18	1	1034	1	1017	0.0e+00	1183	COG3696	Cu/Ag efflux pump CusA	1027
644989229	307	42.91	22	298	9	288	6.0e-71	261	COG0685	5,10-methylenetetrahydrofolate reductase	291
644989230	824	27.27	27	459	3	445	8.0e-72	265	COG0527	Aspartokinase	447
644989231	392	48.71	7	382	10	396	0.0e+00	473	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
644989232	340	28.77	34	338	17	367	1.0e-51	197	COG2021	Homoserine acetyltransferase	368
644989233	98	78.31	4	86	3	85	7.0e-36	141	COG3060	Transcriptional regulator of met regulon	105
644989234	315	53.97	2	299	1	300	8.0e-101	360	COG0031	Cysteine synthase	300
644989235	335	24.75	1	297	1	293	2.0e-39	156	COG0583	DNA-binding transcriptional regulator, LysR family	297
644989236	307	31.15	64	305	18	238	1.0e-47	183	COG4798	Predicted methyltransferase	238
644989237	353	46.88	9	343	1	324	6.0e-109	387	COG0379	Quinolinate synthase	324
644989238	717	19.64	74	690	4	642	6.0e-38	152	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
644989239	441	23.95	1	404	1	356	1.0e-48	187	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
644989240	375	33.77	6	375	3	372	2.0e-54	206	COG2866	Murein tripeptide amidase MpaA	374
644989241	410	19.32	192	393	38	230	3.0e-08	53.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
644989242	229	45.33	5	227	3	225	2.0e-53	202	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644989244	269	30.96	5	224	2	240	2.0e-29	122	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
644989245	359	19.1	8	355	6	342	6.0e-26	111	COG3317	Uncharacterized lipoprotein	342
644989246	293	47.59	1	288	4	293	6.0e-84	304	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
644989247	155	53.55	1	155	1	155	7.0e-57	212	COG1225	Peroxiredoxin	157
644989248	473	48.71	8	473	1	436	0.0e+00	506	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
644989249	562	28.91	8	366	10	385	1.0e-49	191	COG1680	CubicO group peptidase, beta-lactamase class C family	390
644989250	376	35.33	7	355	4	350	4.0e-42	165	COG0628	Predicted PurR-regulated permease PerM	355
644989251	503	34.99	11	490	2	479	4.0e-86	312	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
644989252	158	28.69	15	134	2	123	6.0e-09	53.8	COG0526	Thiol-disulfide isomerase or thioredoxin	127
644989254	397	23.1	1	275	9	298	1.0e-30	127	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
644989255	117	44.74	4	117	3	116	8.0e-30	122	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
644989256	198	29.81	1	198	3	207	1.0e-31	129	COG0655	Multimeric flavodoxin WrbA	207
644989258	364	57.66	2	357	1	354	0.0e+00	486	COG0082	Chorismate synthase	369
644989259	442	35.43	1	424	3	425	5.0e-99	354	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
644989261	301	42.05	1	264	2	262	2.0e-74	272	COG0159	Tryptophan synthase alpha chain	265
644989262	403	65.19	17	401	8	392	0.0e+00	635	COG0133	Tryptophan synthase beta chain	396
644989263	486	47.04	5	246	1	253	1.0e-74	274	COG0134	Indole-3-glycerol phosphate synthase	254
644989264	334	44.74	1	332	5	336	5.0e-103	367	COG0547	Anthranilate phosphoribosyltransferase	338
644989265	206	51.04	1	189	2	191	2.0e-62	231	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
644989266	543	40.94	148	524	106	460	3.0e-101	362	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
644989267	344	59.12	63	335	13	286	1.0e-100	360	COG2876	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	286
644989268	236	28.29	2	211	1	250	6.0e-24	104	COG1192	Cellulose biosynthesis protein BcsQ	259
644989273	188	25	21	154	4	146	9.0e-06	43.5	COG4970	Tfp pilus assembly protein FimT	181
644989274	136	32.09	6	133	2	135	5.0e-16	77	COG4968	Tfp pilus assembly protein PilE	139
644989275	166	26.06	9	162	9	172	4.0e-15	74.7	COG4970	Tfp pilus assembly protein FimT	181
644989280	311	64.07	1	295	2	294	9.0e-121	426	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
644989281	145	40.14	1	142	1	141	1.0e-24	105	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
644989282	177	37.79	1	172	1	166	7.0e-32	130	COG0597	Lipoprotein signal peptidase	167
644989283	938	49.58	2	932	1	933	0.0e+00	1176	COG0060	Isoleucyl-tRNA synthetase	933
644989284	313	47.74	1	310	1	304	5.0e-91	328	COG0196	FAD synthase	304
644989286	510	45.6	1	508	6	515	3.0e-111	395	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
644989287	86	65.12	1	86	1	86	9.0e-13	65.3	COG0268	Ribosomal protein S20	88
644989288	147	30.91	27	136	12	121	4.0e-09	54.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
644989290	183	20.47	55	181	4	110	7.0e-06	43.7	COG1416	Intracellular sulfur oxidation protein, DsrE/DsrF family	112
644989291	424	58.99	1	355	1	351	0.0e+00	478	COG0536	GTPase involved in cell partioning and DNA repair	369
644989292	84	79.27	1	82	1	81	1.0e-28	117	COG0211	Ribosomal protein L27	87
644989293	197	59.8	1	102	1	102	2.0e-34	138	COG0261	Ribosomal protein L21	103
644989294	323	40.8	5	323	1	322	1.0e-75	276	COG0142	Geranylgeranyl pyrophosphate synthase	322
644989295	533	62.59	6	533	9	529	0.0e+00	809	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
644989296	783	33.05	546	780	4	239	3.0e-53	203	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644989298	583	41.12	32	242	25	236	1.0e-27	118	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
644989299	119	29.35	26	117	34	122	3.0e-12	63.9	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
644989301	210	31.52	3	182	11	192	7.0e-16	77.4	COG0558	Phosphatidylglycerophosphate synthase	192
644989302	355	22.05	14	268	10	257	9.0e-22	97.8	COG3249	Uncharacterized protein	343
644989303	187	28.74	14	187	3	174	2.0e-46	178	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
644989304	221	39.47	29	218	1	190	3.0e-39	154	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
644989305	345	65.12	4	345	1	344	0.0e+00	506	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
644989306	207	52.02	3	200	2	199	3.0e-79	288	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
644989309	188	39.06	2	188	1	181	4.0e-58	217	COG0717	Deoxycytidine triphosphate deaminase	183
644989310	362	40.36	44	313	2	265	3.0e-58	219	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
644989311	674	41.46	1	548	1	558	0.0e+00	637	COG0143	Methionyl-tRNA synthetase	558
644989316	580	49.81	45	580	11	539	0.0e+00	630	COG0405	Gamma-glutamyltranspeptidase	539
644989317	93	32.56	1	84	7	92	8.0e-09	51.9	COG1605	Chorismate mutase	101
644989318	329	36.9	1	329	7	312	3.0e-76	278	COG0826	Collagenase-like protease, PrtC family	347
644989319	293	24.59	2	290	1	301	7.0e-38	151	COG0826	Collagenase-like protease, PrtC family	347
644989320	182	34.18	19	176	1	149	3.0e-20	91.5	COG3154	Predicted lipid carrier protein YhbT, SCP2 domain	168
644989321	695	15.37	52	695	75	768	2.0e-14	75	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644989322	151	45.03	1	149	1	150	3.0e-37	147	COG3727	G:T-mismatch repair DNA endonuclease, very short patch repair protein	150
644989326	419	31.76	96	416	3	326	1.0e-57	217	COG0270	Site-specific DNA-cytosine methylase	328
644989329	116	28.28	19	116	1	98	2.0e-11	60.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
644989330	100	46.24	2	94	1	93	3.0e-28	116	COG0776	Bacterial nucleoid DNA-binding protein	94
644989331	792	42.79	145	791	1	650	0.0e+00	658	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
644989332	348	52.94	14	346	6	335	2.0e-124	439	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
644989333	119	74.58	1	118	1	118	1.0e-40	158	COG0292	Ribosomal protein L20	118
644989334	65	58.73	1	63	1	63	7.0e-09	52.1	COG0291	Ribosomal protein L35	65
644989335	179	60.57	5	179	2	176	5.0e-58	216	COG0290	Translation initiation factor IF-3	176
644989336	639	56.01	34	639	1	588	0.0e+00	798	COG0441	Threonyl-tRNA synthetase	589
644989337	150	28.03	1	130	1	132	3.0e-16	78.1	COG3791	Uncharacterized conserved protein	133
644989338	96	36.17	1	94	2	94	2.0e-20	90.4	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
644989339	251	23.74	3	250	2	258	8.0e-10	57.7	COG0730	Uncharacterized membrane protein YfcA	258
644989340	234	37.55	1	234	2	246	4.0e-47	181	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
644989342	361	34.59	163	346	2	180	1.0e-39	157	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644989345	338	40.64	7	338	5	345	1.0e-73	270	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
644989346	477	46.29	3	441	1	441	0.0e+00	472	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
644989348	639	19.05	29	624	15	596	3.0e-22	100	COG4206	Outer membrane cobalamin receptor protein	608
644989351	130	24.82	1	125	1	138	1.0e-12	65.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644989352	346	65.01	1	343	2	344	0.0e+00	533	COG0418	Dihydroorotase	344
644989353	200	27.84	4	194	1	179	8.0e-18	83.7	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
644989355	319	43.81	9	316	2	307	4.0e-77	281	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
644989357	570	20.53	50	568	2	533	3.0e-19	90.6	COG2303	Choline dehydrogenase or related flavoprotein	542
644989358	201	57.65	1	196	1	193	6.0e-74	270	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
644989359	319	20.67	11	309	1	296	3.0e-26	112	COG0583	DNA-binding transcriptional regulator, LysR family	297
644989360	188	30.19	1	187	1	205	3.0e-27	114	COG0655	Multimeric flavodoxin WrbA	207
644989361	76	40.98	1	61	1	61	5.0e-12	62.6	COG2906	Bacterioferritin-associated ferredoxin	63
644989362	159	73.72	1	156	1	156	3.0e-57	213	COG2193	Bacterioferritin (cytochrome b1)	157
644989363	226	34.82	1	225	6	252	2.0e-36	145	COG0584	Glycerophosphoryl diester phosphodiesterase	257
644989365	109	58.25	1	102	1	103	2.0e-42	163	COG0278	Glutaredoxin-related protein	105
644989366	356	40.51	8	352	4	352	4.0e-97	348	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644989367	957	35.86	186	926	1	651	0.0e+00	585	COG0209	Ribonucleotide reductase alpha subunit	696
644989368	421	34.23	85	419	10	339	5.0e-93	334	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
644989374	182	27.22	3	181	2	181	2.0e-24	105	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644989376	478	23.2	7	331	5	365	5.0e-33	135	COG1680	CubicO group peptidase, beta-lactamase class C family	390
644989379	187	22.73	1	180	3	190	3.0e-10	58.4	COG4929	Uncharacterized membrane-anchored protein	190
644989380	444	23.32	9	372	3	377	3.0e-12	66.9	COG4872	Uncharacterized membrane protein	394
644989382	193	54.77	1	193	2	199	1.0e-71	262	COG0605	Superoxide dismutase	204
644989384	303	23.53	28	268	21	260	5.0e-19	88.5	COG0421	Spermidine synthase	282
644989386	391	53.87	1	390	1	393	0.0e+00	492	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
644989388	321	48.72	3	308	1	300	3.0e-104	371	COG0031	Cysteine synthase	300
644989389	745	31.59	401	742	3	321	6.0e-57	216	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
644989391	515	52.39	15	514	15	516	0.0e+00	542	COG2978	p-Aminobenzoyl-glutamate transporter AbgT	516
644989392	273	36	24	271	6	252	6.0e-63	234	COG3228	Mlc titration factor MtfA, regulates ptsG expression	266
644989394	395	51.72	1	395	1	403	0.0e+00	515	COG2081	Predicted flavoprotein YhiN	408
644989396	150	31.01	15	141	9	129	8.0e-18	83.1	COG1765	Uncharacterized OsmC-related protein	137
644989399	453	47.94	1	453	1	459	0.0e+00	542	COG0114	Fumarate hydratase class II	462
644989400	75	34.29	6	75	5	72	2.0e-07	47.2	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
644989401	433	23.39	217	429	63	280	2.0e-13	70.3	COG0842	ABC-type multidrug transport system, permease component	286
644989402	281	41.38	1	277	4	293	4.0e-73	267	COG1131	ABC-type multidrug transport system, ATPase component	293
644989403	161	38.75	1	158	1	149	3.0e-37	147	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
644989405	287	29.41	1	287	15	300	2.0e-27	116	COG1575	1,4-dihydroxy-2-naphthoate octaprenyltransferase	303
644989406	96	36.17	1	94	2	94	2.0e-20	90.7	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
644989408	301	38.72	1	295	1	297	3.0e-62	232	COG2974	DNA recombination-dependent growth factor C	303
644989409	206	46.57	1	204	1	204	6.0e-58	217	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
644989414	105	59.22	1	103	2	104	4.0e-20	89.7	COG2076	Multidrug transporter EmrE and related cation transporters	106
644989415	296	23.39	7	295	1	291	2.0e-26	112	COG0583	DNA-binding transcriptional regulator, LysR family	297
644989416	202	25	1	201	5	247	8.0e-14	70.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644989418	105	59.22	1	103	2	104	4.0e-20	89.7	COG2076	Multidrug transporter EmrE and related cation transporters	106
644989423	275	23.63	44	275	31	258	2.0e-15	76.5	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
644989425	330	37.76	186	328	45	186	2.0e-26	113	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
644989427	570	35.31	59	561	58	551	5.0e-92	331	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
644989430	227	35.89	1	226	1	236	2.0e-46	178	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
644989433	1001	31.35	16	719	28	760	2.0e-121	430	COG4412	Bacillopeptidase F, M6 metalloprotease family	760
644989437	70	44.62	5	69	2	66	4.0e-15	72.9	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
644989439	598	41.27	14	585	3	586	0.0e+00	541	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
644989440	161	28.08	17	156	13	151	7.0e-07	47	COG1714	Uncharacterized membrane protein YckC, RDD family	172
644989442	354	27.22	1	352	1	360	2.0e-40	160	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
644989443	370	27.6	1	353	2	363	3.0e-39	156	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
644989444	496	49	1	496	1	485	0.0e+00	551	COG0260	Leucyl aminopeptidase	485
644989445	142	33.8	1	139	1	138	1.0e-25	109	COG2927	DNA polymerase III, chi subunit	144
644989446	179	30.39	4	179	15	194	6.0e-23	100	COG3963	Phospholipid N-methyltransferase	194
644989447	923	57.34	1	921	1	876	0.0e+00	1258	COG0525	Valyl-tRNA synthetase	877
644989450	853	34.33	499	852	30	394	3.0e-79	290	COG0019	Diaminopimelate decarboxylase	394
644989450	853	34.68	9	453	5	446	4.0e-90	326	COG0527	Aspartokinase	447
644989451	159	50.66	1	151	1	152	1.0e-46	178	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
644989452	525	69.91	207	525	1	315	0.0e+00	550	COG0519	GMP synthase, PP-ATPase domain/subunit	315
644989453	487	31.22	255	475	1	169	1.0e-34	141	COG0516	IMP dehydrogenase/GMP reductase	170
644989454	451	48.39	15	448	3	433	0.0e+00	479	COG1570	Exonuclease VII, large subunit	440
644989456	467	48.77	1	444	2	444	0.0e+00	544	COG1160	Predicted GTPases	444
644989457	388	24.09	3	336	4	359	4.0e-33	136	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
644989458	207	33.01	2	205	3	207	1.0e-29	122	COG2976	Putative negative regulator of RcsB-dependent stress response	207
644989459	423	49.76	2	408	1	415	0.0e+00	490	COG0124	Histidyl-tRNA synthetase	429
644989460	379	65.55	7	362	1	357	0.0e+00	530	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
644989461	303	21.28	15	271	3	284	4.0e-26	112	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
644989462	263	32.18	1	261	1	248	4.0e-43	168	COG3063	Tfp pilus assembly protein PilF	250
644989463	374	55.93	5	356	1	349	2.0e-128	452	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
644989464	143	67.41	2	136	1	135	5.0e-58	216	COG0105	Nucleoside diphosphate kinase	135
644989466	224	55.11	1	223	1	219	2.0e-77	282	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
644989467	213	32.27	1	209	1	212	4.0e-36	144	COG0602	Organic radical activating enzyme	212
644989468	243	27.97	1	243	2	261	2.0e-26	112	COG1729	Periplasmic TolA-binding protein (function unknown)	262
644989469	172	34.59	40	171	55	187	1.0e-26	112	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
644989470	454	39.91	9	452	3	424	1.0e-91	330	COG0823	Periplasmic component of the Tol biopolymer transport system	425
644989472	142	40.29	1	139	1	132	2.0e-28	118	COG0848	Biopolymer transport protein ExbD	137
644989473	237	42.72	23	235	1	213	2.0e-50	192	COG0811	Biopolymer transport protein ExbB/TolQ	216
644989474	139	39.71	1	136	1	133	2.0e-30	124	COG0824	Acyl-CoA thioesterase FadM	137
644989475	339	70.82	4	332	1	329	0.0e+00	529	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
644989476	657	43.89	1	534	3	530	0.0e+00	530	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644989478	145	26.32	13	144	8	139	5.0e-15	73.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
644989484	343	38.65	176	337	12	173	1.0e-34	140	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644989485	205	45.37	1	203	1	200	7.0e-54	203	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
644989486	176	57.05	5	159	1	152	6.0e-50	190	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
644989487	247	60.17	1	240	1	240	2.0e-93	335	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
644989488	590	61.97	5	588	1	585	0.0e+00	918	COG0173	Aspartyl-tRNA synthetase	585
644989490	701	15.9	59	701	71	768	4.0e-18	87.3	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644989491	409	29.53	18	398	6	408	5.0e-75	275	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644989492	549	39.59	22	549	2	532	9.0e-120	424	COG1574	Predicted amidohydrolase YtcJ	535
644989494	571	45.18	1	567	1	500	0.0e+00	586	COG0442	Prolyl-tRNA synthetase	500
644989496	408	24	9	306	13	258	4.0e-23	102	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
644989499	423	32.13	25	294	23	286	4.0e-41	162	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
644989500	319	67.51	2	318	1	317	0.0e+00	495	COG0825	Acetyl-CoA carboxylase alpha subunit	317
644989501	461	36.76	1	185	2	179	3.0e-46	179	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
644989502	160	41.32	5	158	2	168	3.0e-42	164	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
644989503	212	30.86	27	181	29	190	1.0e-26	113	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
644989507	225	32.85	20	224	11	182	7.0e-26	110	COG0693	Putative intracellular protease/amidase	188
644989508	126	20.14	1	115	1	136	6.0e-06	43.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644989510	475	22.8	35	440	10	398	2.0e-30	127	COG1228	Imidazolonepropionase or related amidohydrolase	406
644989512	344	60.7	1	341	4	340	0.0e+00	490	COG2130	NADPH-dependent curcumin reductase CurA	340
644989515	175	46.15	3	54	6	57	1.0e-07	49.4	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
644989517	1161	50.18	2	1120	1	1107	0.0e+00	1331	COG0587	DNA polymerase III, alpha subunit	1139
644989518	191	60.32	6	190	1	189	7.0e-65	240	COG0164	Ribonuclease HII	199
644989519	397	45.33	17	388	3	374	1.0e-118	419	COG0763	Lipid A disaccharide synthetase	381
644989520	252	54.12	2	252	6	260	2.0e-96	345	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
644989521	156	55.48	11	154	3	145	3.0e-47	181	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
644989522	349	51.94	4	336	5	338	6.0e-96	344	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
644989523	166	29.17	1	166	3	169	9.0e-16	76.5	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
644989524	823	34.55	4	823	3	766	0.0e+00	551	COG4775	Outer membrane protein assembly factor BamA	766
644989526	399	55.58	6	398	2	385	0.0e+00	527	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
644989527	296	32.07	1	289	1	265	1.0e-26	113	COG0575	CDP-diglyceride synthetase	265
644989528	240	54.31	10	234	14	245	3.0e-87	314	COG0020	Undecaprenyl pyrophosphate synthase	245
644989529	185	61.62	1	185	3	187	2.0e-59	221	COG0233	Ribosome recycling factor	187
644989530	238	60.17	4	238	3	238	5.0e-88	317	COG0528	Uridylate kinase	238
644989531	289	59.66	1	288	2	296	1.0e-92	332	COG0264	Translation elongation factor EF-Ts	296
644989532	244	61.13	1	244	1	246	3.0e-98	351	COG0052	Ribosomal protein S2	252
644989534	299	28.08	27	284	24	280	1.0e-27	117	COG1398	Fatty-acid desaturase	289
644989539	116	57.39	2	116	3	117	3.0e-40	157	COG5507	Uncharacterized  conserved protein YbaA, DUF1428 family	117
644989540	278	53.43	1	275	1	255	1.0e-94	339	COG0024	Methionine aminopeptidase	255
644989541	882	41.74	13	881	4	862	0.0e+00	764	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
644989542	274	51.26	1	270	2	269	6.0e-81	294	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
644989543	121	33.33	3	120	1	115	6.0e-25	106	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
644989544	381	34.42	1	377	12	409	6.0e-78	284	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644989545	237	25	1	202	21	220	2.0e-18	86.6	COG1876	LD-carboxypeptidase LdcB, LAS superfamily	241
644989547	464	26.51	5	461	3	455	8.0e-42	165	COG0471	Di- and tricarboxylate transporter	461
644989548	246	34.26	1	246	3	253	7.0e-49	187	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
644989549	233	37.39	1	227	13	234	1.0e-43	169	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
644989550	149	60.67	1	147	1	150	9.0e-52	195	COG0328	Ribonuclease HI	154
644989552	265	25.48	3	230	16	248	1.0e-18	87.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644989553	516	32.26	355	469	1	121	3.0e-09	57.2	COG1388	LysM repeat	124
644989554	414	18.96	1	413	4	400	3.0e-18	86.6	COG1668	ABC-type Na+ efflux pump, permease component	407
644989555	264	43.56	38	262	17	241	4.0e-61	228	COG4555	ABC-type Na+ transport system, ATPase component NatA	245
644989556	360	29.69	55	346	57	348	2.0e-48	187	COG3768	Uncharacterized membrane protein YcjF, UPF0283 family	350
644989557	466	40.98	1	466	2	467	4.0e-128	451	COG3106	Predicted ATPase, YcjX-like family	467
644989561	133	31.78	4	130	6	133	4.0e-16	77.2	COG0848	Biopolymer transport protein ExbD	137
644989566	558	28.35	1	545	2	556	6.0e-90	325	COG0747	ABC-type transport system, periplasmic component	556
644989567	319	39.29	1	317	1	315	6.0e-65	241	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644989568	287	47.45	9	282	19	292	3.0e-67	248	COG4171	ABC-type antimicrobial peptide transport system, permease component	296
644989569	326	50.47	3	319	1	315	7.0e-106	377	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
644989571	624	22.26	119	392	31	292	7.0e-06	46.2	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
644989574	90	68.89	1	90	2	91	3.0e-28	116	COG0776	Bacterial nucleoid DNA-binding protein	94
644989575	802	67.44	5	778	5	780	0.0e+00	1179	COG0466	ATP-dependent Lon protease, bacterial type	782
644989576	422	71.57	14	421	1	405	0.0e+00	688	COG1219	ATP-dependent protease Clp, ATPase subunit	408
644989578	444	15.96	17	390	17	446	3.0e-17	83.3	COG3202	ATP/ADP translocase	509
644989579	205	70.83	12	203	3	194	1.0e-83	302	COG0740	ATP-dependent protease ClpP, protease subunit	200
644989580	432	43.38	1	426	1	438	4.0e-102	365	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
644989585	284	61.21	4	284	1	281	2.0e-111	395	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
644989588	319	51.8	15	319	7	303	2.0e-88	319	COG4589	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase	303
644989589	196	27.81	15	196	1	185	1.0e-12	66.2	COG0558	Phosphatidylglycerophosphate synthase	192
644989591	465	58.67	1	465	1	464	0.0e+00	681	COG0215	Cysteinyl-tRNA synthetase	464
644989592	171	49.69	8	168	2	156	4.0e-50	190	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
644989593	238	38.63	4	232	2	229	3.0e-49	188	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
644989594	188	50.29	10	184	12	178	1.0e-43	169	COG3803	Uncharacterized conserved protein, DUF924 family	182
644989596	240	44.14	8	221	2	223	3.0e-49	188	COG3340	Peptidase E	224
644989597	205	52.91	1	205	1	203	3.0e-59	221	COG4445	tRNA isopentenyl-2-thiomethyl-A-37 hydroxylase MiaE (synthesis of 2-methylthio-cis-ribozeatin)	203
644989598	674	21.27	235	541	14	314	5.0e-21	96.7	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
644989599	316	22.85	37	316	4	301	3.0e-20	92.9	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
644989600	305	41.64	1	303	11	327	8.0e-65	240	COG0714	MoxR-like ATPase	329
644989604	715	41.98	322	610	5	296	2.0e-82	301	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
644989605	439	32.11	15	439	2	392	4.0e-63	236	COG0183	Acetyl-CoA acetyltransferase	392
644989606	319	41.77	1	319	9	328	6.0e-65	241	COG0714	MoxR-like ATPase	329
644989612	252	31.66	1	246	1	247	2.0e-32	132	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644989614	1612	44.04	1	1607	1	1592	0.0e+00	1685	COG2902	NAD-specific glutamate dehydrogenase	1592
644989615	882	19.41	12	619	7	563	5.0e-44	173	COG1033	Predicted exporter protein, RND superfamily	727
644989616	335	20.94	11	327	11	325	2.0e-24	107	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
644989621	285	31.63	1	282	1	293	5.0e-48	184	COG1131	ABC-type multidrug transport system, ATPase component	293
644989622	124	35.48	1	124	2	124	1.0e-19	88.4	COG1725	DNA-binding transcriptional regulator YhcF, GntR family	125
644989623	338	30.34	76	334	68	331	7.0e-36	144	COG2855	Uncharacterized membrane protein YadS	334
644989624	296	38.83	9	293	1	277	2.0e-60	226	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
644989626	316	51.72	3	316	6	322	1.0e-96	346	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
644989627	187	44.27	1	131	1	131	7.0e-38	150	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
644989628	349	42.94	7	344	3	342	2.0e-96	346	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
644989630	689	24.31	251	429	2	181	9.0e-21	96	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644989631	293	46.6	80	284	6	211	2.0e-50	192	COG0560	Phosphoserine phosphatase	212
644989633	746	42.91	4	744	6	747	0.0e+00	774	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
644989634	629	47.02	1	629	1	632	0.0e+00	834	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
644989635	274	25.1	15	251	1	247	5.0e-28	118	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
644989636	158	34.51	5	146	7	140	5.0e-21	93.9	COG3151	Uncharacterized protein YqiB, DUF1249 family	147
644989638	222	37.74	11	222	1	209	4.0e-56	211	COG2518	Protein-L-isoaspartate O-methyltransferase	209
644989639	457	25.59	28	451	45	454	9.0e-47	181	COG1538	Outer membrane protein TolC	457
644989640	423	44.55	10	423	1	419	2.0e-119	423	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
644989641	97	58.06	5	97	2	94	3.0e-29	119	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
644989642	143	50.35	1	142	1	143	2.0e-44	171	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
644989643	157	59.6	7	157	2	151	9.0e-57	212	COG0691	tmRNA-binding protein	153
644989645	570	26.45	12	303	2	308	8.0e-39	155	COG0515	Serine/threonine protein kinase	384
644989647	267	34.39	2	237	1	249	1.0e-45	176	COG0631	Serine/threonine protein phosphatase PrpC	262
644989648	190	29.21	1	170	9	184	6.0e-22	97.4	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
644989649	269	24.75	9	266	24	313	6.0e-28	117	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
644989653	322	48.43	1	317	8	318	9.0e-54	204	COG0530	Ca2+/Na+ antiporter	320
644989654	485	30.09	54	474	24	443	4.0e-50	192	COG1538	Outer membrane protein TolC	457
644989656	237	43.11	6	229	2	224	3.0e-62	231	COG1136	ABC-type lipoprotein export system, ATPase component	226
644989657	400	19.16	12	397	26	404	2.0e-10	60.7	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
644989658	393	26.65	9	369	1	352	7.0e-26	111	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644989659	202	25.13	1	187	1	185	2.0e-11	62.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644989660	148	40.94	1	148	1	149	1.0e-31	128	COG1959	DNA-binding transcriptional regulator, IscR family	150
644989661	139	39.82	27	138	6	118	2.0e-17	81.8	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
644989662	433	28.81	26	373	23	376	1.0e-25	111	COG3213	Uncharacterized protein involved in response to NO	396
644989663	229	50.23	6	222	1	217	2.0e-70	259	COG2846	Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains	221
644989664	759	47.31	4	746	2	714	0.0e+00	698	COG3256	Nitric oxide reductase large subunit	717
644989665	720	16.93	8	720	32	768	1.0e-31	132	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644989666	447	42.32	17	433	7	428	2.0e-120	426	COG3486	Lysine/ornithine N-monooxygenase	436
644989667	620	31.7	12	589	12	599	3.0e-108	386	COG4264	Siderophore synthetase component	602
644989669	609	24.03	9	592	26	601	1.0e-60	227	COG4264	Siderophore synthetase component	602
644989672	522	18.6	27	426	11	422	3.0e-26	113	COG3182	Uncharacterized iron-regulated membrane protein	442
644989673	283	38.94	6	282	10	312	1.0e-71	263	COG0627	S-formylglutathione hydrolase FrmB	316
644989674	374	72.09	6	374	1	366	0.0e+00	588	COG1062	Zn-dependent alcohol dehydrogenase	366
644989676	670	26.89	1	609	1	509	1.0e-91	331	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
644989677	356	29.41	42	351	5	316	3.0e-56	212	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
644989679	473	24.83	9	436	3	449	6.0e-35	142	COG0591	Na+/proline symporter	493
644989681	404	24.18	25	397	33	408	1.0e-37	150	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644989682	182	30.41	15	180	6	175	5.0e-26	110	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644989683	231	28.64	12	221	17	232	3.0e-26	112	COG5343	Anti-sigma-K factor RskA	240
644989688	159	39.44	1	138	7	145	8.0e-26	109	COG0071	Molecular chaperone IbpA, HSP20 family	146
644989689	655	24.92	38	655	63	619	2.0e-57	217	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
644989690	278	52.17	25	277	12	259	2.0e-86	312	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
644989693	432	33.44	1	298	1	297	4.0e-50	192	COG1893	Ketopantoate reductase	307
644989697	200	20	12	196	3	201	5.0e-18	84.6	COG0778	Nitroreductase	207
644989699	806	23.59	229	806	95	618	6.0e-58	219	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
644989700	571	22.17	156	569	17	434	3.0e-43	170	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
644989701	548	33.94	384	548	18	180	7.0e-30	126	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644989702	269	34.88	12	266	7	259	2.0e-50	192	COG0300	Short-chain dehydrogenase	265
644989703	429	50.36	6	420	4	409	0.0e+00	487	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
644989704	301	28.96	6	297	1	297	3.0e-44	172	COG0583	DNA-binding transcriptional regulator, LysR family	297
644989705	317	42.41	3	315	11	317	1.0e-82	299	COG4874	Uncharacterized protein	318
644989707	469	20.48	42	440	10	404	9.0e-18	85.4	COG1228	Imidazolonepropionase or related amidohydrolase	406
644989708	435	24.16	14	430	3	382	3.0e-41	163	COG5505	Uncharacterized membrane protein	384
644989709	155	25.16	1	153	1	154	8.0e-12	63.4	COG4539	Uncharacterized membrane protein YGL010W	180
644989710	135	58.21	1	132	1	129	3.0e-40	157	COG1970	Large-conductance mechanosensitive channel	130
644989711	287	30.36	5	285	14	315	4.0e-42	165	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
644989713	319	33.23	3	310	6	318	1.0e-46	180	COG0226	ABC-type phosphate transport system, periplasmic component	318
644989715	745	18.94	5	745	5	768	9.0e-43	168	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644989716	174	35.22	12	168	1	145	3.0e-32	131	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
644989717	405	48.43	1	404	2	412	2.0e-122	433	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644989719	428	27.86	73	422	86	443	5.0e-49	188	COG5002	Signal transduction histidine kinase	459
644989720	230	45.22	4	230	2	228	3.0e-66	244	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644989721	243	37.61	10	243	8	237	1.0e-42	166	COG0704	Phosphate uptake regulator	240
644989722	281	75.81	34	281	7	253	0.0e+00	468	COG1117	ABC-type phosphate transport system, ATPase component	253
644989723	535	42.75	263	530	49	292	7.0e-70	258	COG0581	ABC-type phosphate transport system, permease component	292
644989724	746	46.82	19	746	9	733	0.0e+00	712	COG4590	ABC-type uncharacterized transport system, permease component	733
644989725	378	30.91	1	378	5	426	5.0e-44	172	COG3746	Phosphate-selective porin	426
644989731	364	26.5	42	240	13	182	1.0e-17	84.8	COG0693	Putative intracellular protease/amidase	188
644989733	228	38.5	6	225	3	227	2.0e-52	199	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644989734	413	24.39	126	397	27	312	3.0e-18	86.8	COG0642	Signal transduction histidine kinase	336
644989735	361	24.8	9	249	44	292	1.0e-13	71.1	COG0668	Small-conductance mechanosensitive channel	316
644989736	233	19.07	1	233	2	231	8.0e-13	67.6	COG0670	Integral membrane protein, interacts with FtsH	233
644989737	154	45.78	5	154	2	167	6.0e-38	149	COG0629	Single-stranded DNA-binding protein	167
644989738	454	23.48	4	393	1	390	4.0e-20	93	COG2814	Predicted arabinose efflux permease, MFS family	394
644989739	941	67.06	1	941	3	934	0.0e+00	1582	COG0178	Excinuclease UvrABC ATPase subunit	935
644989740	271	25.58	3	258	11	254	4.0e-25	108	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
644989741	566	45.86	431	557	2	134	2.0e-37	151	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
644989742	555	46.59	3	537	1	530	0.0e+00	570	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644989744	207	23.89	26	196	48	227	4.0e-15	75	COG0220	tRNA G46 methylase TrmB	227
644989746	454	58.46	1	454	1	453	0.0e+00	625	COG1066	Predicted ATP-dependent serine protease	456
644989747	459	44.27	6	437	2	435	0.0e+00	470	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
644989750	277	42.65	9	275	1	271	1.0e-63	236	COG0338	Site-specific DNA-adenine methylase	274
644989751	200	47.42	8	195	15	207	1.0e-48	185	COG3571	Predicted hydrolase of the alpha/beta-hydrolase fold	213
644989752	126	50	4	125	1	122	7.0e-31	126	COG0818	Diacylglycerol kinase	123
644989754	236	37.56	4	214	1	205	9.0e-50	190	COG0132	Dethiobiotin synthetase	223
644989757	258	26.22	6	256	13	279	8.0e-22	97.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644989758	389	49.87	3	379	5	385	4.0e-123	435	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
644989759	374	56.78	20	334	9	323	1.0e-117	416	COG0502	Biotin synthase or related enzyme	335
644989760	235	40.54	16	235	10	223	2.0e-46	179	COG1040	Predicted amidophosphoribosyltransferases	225
644989763	442	30.28	9	441	18	450	8.0e-55	208	COG0534	Na+-driven multidrug efflux pump	455
644989768	192	38.38	1	99	4	100	2.0e-27	115	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
644989769	460	30.11	7	459	2	445	6.0e-78	284	COG0527	Aspartokinase	447
644989770	77	38.89	22	75	10	61	3.0e-08	50	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
644989771	959	41.08	15	957	24	958	0.0e+00	749	COG1391	Glutamine synthetase adenylyltransferase	963
644989772	195	50	1	192	2	185	5.0e-53	200	COG1704	Uncharacterized conserved protein	185
644989773	644	22.83	18	326	9	293	3.0e-20	93.8	COG0501	Zn-dependent protease with chaperone function	302
644989776	498	28.42	1	465	1	419	1.0e-50	194	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
644989777	224	35.59	3	224	1	216	7.0e-44	170	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
644989778	426	32.48	9	242	2	231	3.0e-32	133	COG0306	Phosphate/sulfate permease	326
644989779	196	27.8	6	195	4	204	1.0e-15	76.5	COG3103	Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family	205
644989780	1052	51.33	454	1052	7	593	0.0e+00	764	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
644989781	479	34.3	6	308	55	354	1.0e-71	264	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
644989782	957	24.78	28	477	1	436	1.0e-41	165	COG0612	Predicted Zn-dependent peptidase	438
644989784	563	38.49	1	250	9	257	9.0e-52	198	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
644989786	411	32.99	1	388	23	402	2.0e-73	270	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
644989787	274	36.13	1	274	4	270	8.0e-56	210	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
644989789	404	35.41	46	387	12	359	3.0e-70	259	COG1565	SAM-dependent methyltransferase, MidA family	370
644989790	238	32.93	1	235	2	249	3.0e-34	138	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644989791	167	33.75	1	155	1	158	7.0e-27	113	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
644989792	117	37.29	1	117	2	119	2.0e-28	117	COG1539	Dihydroneopterin aldolase	121
644989793	196	41.88	10	193	10	200	2.0e-44	171	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
644989795	392	21.57	1	388	6	391	8.0e-15	75.2	COG2814	Predicted arabinose efflux permease, MFS family	394
644989798	340	53.33	1	340	1	338	1.0e-126	446	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
644989799	71	58.21	1	67	1	67	3.0e-06	43.7	COG0828	Ribosomal protein S21	67
644989800	148	53.06	2	147	1	147	5.0e-37	146	COG1610	Uncharacterized conserved protein YqeY	148
644989801	592	38.8	4	585	2	567	4.0e-129	455	COG0358	DNA primase (bacterial type)	568
644989802	616	50.14	259	615	1	342	5.0e-94	338	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
644989806	76	63.51	1	73	1	74	9.0e-19	84.9	COG4572	Cation transport regulator ChaB	76
644989809	332	20.66	39	280	65	257	4.0e-10	59.3	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
644989810	450	20.59	26	433	13	403	3.0e-15	76.9	COG1228	Imidazolonepropionase or related amidohydrolase	406
644989811	751	25	8	265	1	272	6.0e-23	103	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644989811	751	40.66	501	739	15	254	5.0e-63	236	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644989816	313	29.12	30	306	26	304	3.0e-44	172	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
644989818	354	28.4	12	348	5	324	1.0e-52	200	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
644989823	229	21.7	8	212	3	214	3.0e-17	82.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
644989824	1034	25.12	1	1020	2	1004	0.0e+00	594	COG0841	Multidrug efflux pump subunit AcrB	1009
644989825	408	23.5	44	388	33	368	4.0e-15	76.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644989826	944	26.3	88	921	29	847	7.0e-106	379	COG0308	Aminopeptidase N	859
644989827	399	15.36	55	369	55	358	8.0e-08	51.7	COG2814	Predicted arabinose efflux permease, MFS family	394
644989828	913	25.06	59	893	29	850	4.0e-107	383	COG0308	Aminopeptidase N	859
644989831	901	55.7	8	899	5	861	0.0e+00	1126	COG1048	Aconitase A	861
644989832	368	24.23	18	343	3	247	6.0e-43	168	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
644989833	96	42.71	1	96	1	95	2.0e-24	103	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
644989835	269	28	65	264	1	174	8.0e-28	117	COG1076	DnaJ-domain-containing proteins 1	174
644989837	344	39.81	34	329	37	344	2.0e-70	259	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
644989838	786	28.28	91	780	55	780	3.0e-105	376	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
644989839	427	20.99	2	335	1	319	3.0e-13	69.7	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
644989840	332	49.7	6	331	5	331	4.0e-103	368	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
644989841	269	50.4	11	259	3	250	4.0e-89	321	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
644989843	213	37.26	3	211	1	201	2.0e-50	192	COG0461	Orotate phosphoribosyltransferase	201
644989845	197	20.79	1	178	5	180	1.0e-07	50	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644989846	806	35.73	356	802	9	464	5.0e-99	355	COG1109	Phosphomannomutase	464
644989847	399	46.97	2	395	1	387	2.0e-111	395	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
644989848	224	54.02	1	224	1	224	4.0e-75	274	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
644989849	78	66.23	1	76	1	77	1.0e-20	91.5	COG0227	Ribosomal protein L28	77
644989850	51	46.94	1	49	2	50	2.0e-10	57.5	COG0267	Ribosomal protein L33	50
644989851	269	54.21	1	269	1	273	5.0e-95	341	COG0266	Formamidopyrimidine-DNA glycosylase	273
644989852	138	23.14	16	136	13	131	2.0e-13	67.9	COG0848	Biopolymer transport protein ExbD	137
644989853	138	22.73	1	132	3	131	9.0e-17	79.5	COG0848	Biopolymer transport protein ExbD	137
644989855	123	28.1	4	120	11	127	2.0e-12	64.6	COG0727	Fe-S-cluster containining protein	132
644989856	253	26.75	17	243	14	250	5.0e-24	104	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
644989858	160	58.49	1	159	1	159	1.0e-62	232	COG0669	Phosphopantetheine adenylyltransferase	159
644989859	517	21.39	16	515	5	538	5.0e-55	209	COG2303	Choline dehydrogenase or related flavoprotein	542
644989861	460	32.05	1	437	38	472	4.0e-88	318	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644989862	332	42.81	7	332	19	341	3.0e-83	302	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
644989863	355	54.8	1	353	1	352	0.0e+00	462	COG0407	Uroporphyrinogen-III decarboxylase	352
644989865	360	48.41	15	359	13	358	1.0e-112	399	COG0337	3-dehydroquinate synthetase	360
644989866	174	50.3	3	171	1	168	1.0e-50	192	COG0703	Shikimate kinase	172
644989867	701	32.44	32	697	16	709	4.0e-107	382	COG4796	Type II secretory pathway, component HofQ	709
644989868	186	32.95	12	184	5	166	7.0e-29	120	COG3168	Tfp pilus assembly protein PilP	170
644989869	209	39.71	1	209	5	200	2.0e-46	178	COG3167	Tfp pilus assembly protein PilO	211
644989870	191	29.61	1	179	4	182	4.0e-24	104	COG3166	Tfp pilus assembly protein PilN	206
644989871	355	48.16	3	355	2	354	2.0e-101	362	COG4972	Tfp pilus assembly protein, ATPase PilM	354
644989872	879	42.91	5	825	1	795	0.0e+00	843	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
644989873	69	57.75	1	67	1	71	8.0e-21	91.9	COG0254	Ribosomal protein L31	75
644989879	730	47.33	6	728	2	729	0.0e+00	787	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
644989881	179	72.88	3	179	1	177	4.0e-76	277	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
644989882	444	68.01	1	444	2	444	0.0e+00	685	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
644989884	134	50.43	7	122	3	119	2.0e-34	137	COG3536	Uncharacterized conserved protein, DUF971 family	120
644989885	255	59.58	17	255	1	238	7.0e-85	306	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
644989886	209	24.12	4	202	5	203	4.0e-29	121	COG3165	Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain	204
644989887	548	43.13	1	520	1	516	0.0e+00	510	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
644989888	112	41.35	2	105	1	104	2.0e-26	110	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
644989889	86	33.33	3	86	4	87	1.0e-10	58.4	COG1826	Sec-independent protein translocase protein TatA	94
644989890	124	29.59	3	100	2	93	1.0e-11	61.9	COG1826	Sec-independent protein translocase protein TatA	94
644989891	250	43.48	1	250	2	254	2.0e-52	199	COG0805	Sec-independent protein secretion pathway component TatC	255
644989893	451	21.35	48	407	7	346	7.0e-09	55.5	COG0006	Xaa-Pro aminopeptidase	384
644989894	427	45.6	246	426	1	181	4.0e-50	192	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644989895	194	20.77	12	193	13	194	1.0e-13	70.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644989896	374	36.74	4	361	15	366	4.0e-30	126	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644989897	1046	46.36	1	1026	2	1009	0.0e+00	938	COG0841	Multidrug efflux pump subunit AcrB	1009
644989898	466	34.29	12	461	1	445	4.0e-64	239	COG1538	Outer membrane protein TolC	457
644989899	348	27.65	12	347	17	352	3.0e-30	126	COG0628	Predicted PurR-regulated permease PerM	355
644989900	268	40.08	7	266	1	256	8.0e-71	260	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
644989901	625	26.5	392	622	3	221	4.0e-25	110	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
644989903	145	57.93	1	145	1	145	2.0e-54	205	COG1490	D-Tyr-tRNAtyr deacylase	145
644989905	607	68.94	1	602	1	601	0.0e+00	1017	COG1217	Predicted membrane GTPase involved in stress response	603
644989906	700	39.78	516	696	1	179	1.0e-38	155	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644989907	698	36.21	519	692	6	177	4.0e-36	146	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644989908	362	18.86	16	332	2	338	4.0e-35	142	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
644989909	77	37.33	1	74	2	76	4.0e-15	73	COG0425	TusA-related sulfurtransferase	78
644989914	469	49.37	1	469	1	443	0.0e+00	521	COG0174	Glutamine synthetase	443
644989916	356	37.07	5	345	11	356	1.0e-65	243	COG3852	Signal transduction histidine kinase, nitrogen specific	363
644989918	153	58.55	1	151	2	153	1.0e-61	228	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
644989919	334	56.4	6	333	3	329	1.0e-118	419	COG0240	Glycerol-3-phosphate dehydrogenase	329
644989920	169	43.62	19	167	8	156	4.0e-38	151	COG1952	Preprotein translocase subunit SecB	157
644989921	87	50	2	79	1	80	2.0e-20	90.4	COG0695	Glutaredoxin	80
644989922	141	33.03	34	141	1	109	2.0e-19	88.1	COG0607	Rhodanese-related sulfurtransferase	110
644989923	154	43.57	9	147	5	137	9.0e-26	109	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
644989924	303	42.37	5	293	5	289	5.0e-49	188	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
644989925	511	60.31	4	510	2	509	0.0e+00	723	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
644989926	369	31.81	10	369	28	419	2.0e-60	226	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
644989927	416	40.83	27	379	20	375	1.0e-88	320	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
644989930	181	21.62	44	181	11	156	1.0e-06	46.5	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
644989931	224	20.8	12	224	1	224	2.0e-15	76.1	COG1011	FMN phosphatase YigB, HAD superfamily	229
644989933	160	24.84	8	158	28	178	2.0e-12	65.4	COG3149	Type II secretory pathway, component PulM	181
644989934	411	21.41	5	410	7	390	7.0e-18	85.4	COG3297	Type II secretory pathway, component PulL	390
644989935	361	25.98	19	345	5	302	2.0e-30	127	COG3156	Type II secretory pathway, component PulK	323
644989936	234	22.8	11	202	9	192	9.0e-15	73.9	COG4795	Type II secretory pathway, component PulJ	194
644989939	156	38.26	2	144	1	149	4.0e-19	87.4	COG2165	Type II secretory pathway, pseudopilin PulG	149
644989940	407	42.47	1	405	1	396	4.0e-101	361	COG1459	Type II secretory pathway, component PulF	397
644989941	511	51.85	28	510	20	500	0.0e+00	573	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
644989942	708	31.46	38	655	38	561	2.0e-85	310	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
644989943	316	21	17	292	8	268	9.0e-19	87.8	COG3031	Type II secretory pathway, component PulC	275
644989944	128	61.54	7	97	9	99	1.0e-24	105	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
644989945	290	39.1	1	279	3	286	1.0e-66	246	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
644989946	434	29.9	157	434	42	330	4.0e-38	152	COG0642	Signal transduction histidine kinase	336
644989947	240	44.64	6	237	1	229	5.0e-62	230	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644989948	773	55.77	1	773	7	779	0.0e+00	958	COG2183	Transcriptional accessory protein Tex/SPT6	780
644989949	170	35.19	4	163	11	166	5.0e-18	84.3	COG1495	Disulfide bond formation protein DsbB	170
644989951	108	50.53	7	101	10	104	3.0e-26	110	COG4323	Uncharacterized protein	105
644989952	328	42.2	54	270	2	205	9.0e-44	170	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
644989954	126	40.65	1	121	1	122	1.0e-13	68.3	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
644989955	499	37.46	16	298	18	308	3.0e-63	236	COG1560	Lauroyl/myristoyl acyltransferase	308
644989956	456	29.52	14	444	11	446	8.0e-50	191	COG0534	Na+-driven multidrug efflux pump	455
644989957	216	29.38	3	205	1	206	6.0e-32	130	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
644989958	315	47.39	23	309	17	299	1.0e-81	296	COG0109	Polyprenyltransferase (heme O synthase)	304
644989959	369	26.57	4	350	19	309	7.0e-37	148	COG1612	Heme A synthase	323
644989961	261	22.83	8	254	3	243	1.0e-22	100	COG3346	Cytochrome oxidase assembly protein ShyY1	252
644989965	360	30.58	9	292	1	288	4.0e-51	195	COG0859	ADP-heptose:LPS heptosyltransferase	334
644989966	217	25.86	13	126	13	126	6.0e-14	71.1	COG3710	DNA-binding winged helix-turn-helix (wHTH) domain	148
644989972	633	33.76	138	633	5	542	6.0e-102	365	COG1982	Arginine/lysine/ornithine decarboxylase	557
644989979	152	43.33	1	90	1	85	7.0e-14	70.2	COG1314	Preprotein translocase subunit SecG	86
644989980	250	50.4	1	249	1	247	1.0e-74	272	COG0149	Triosephosphate isomerase	251
644989981	448	58.71	1	448	1	447	0.0e+00	614	COG1726	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA	447
644989982	401	62.25	2	396	1	399	6.0e-127	447	COG1805	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB	400
644989983	253	50.58	2	253	5	261	2.0e-79	289	COG2869	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC	264
644989984	211	70.73	4	208	3	207	2.0e-81	294	COG1347	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD	208
644989985	202	77.72	1	202	1	198	4.0e-75	274	COG2209	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE	198
644989986	408	75.25	1	408	3	410	0.0e+00	714	COG2871	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF	410
644989987	335	36.87	1	334	3	337	9.0e-79	287	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
644989989	72	50	4	59	3	58	6.0e-15	72.7	COG2991	Uncharacterized protein	77
644989991	377	38.36	210	368	31	184	5.0e-35	142	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
644989992	443	48.26	1	443	4	461	3.0e-123	435	COG1109	Phosphomannomutase	464
644989993	271	49.25	7	271	5	268	5.0e-72	264	COG0294	Dihydropteroate synthase	274
644989994	641	58.64	9	608	1	596	0.0e+00	759	COG0465	ATP-dependent Zn proteases	596
644989995	206	59.11	4	206	1	203	2.0e-73	268	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
644989996	109	47.92	15	109	2	97	4.0e-23	99.5	COG1534	RNA-binding protein YhbY	97
644989997	227	44.74	5	227	3	229	3.0e-54	205	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644989998	434	24.7	115	434	18	334	6.0e-34	138	COG0642	Signal transduction histidine kinase	336
644989999	344	26.17	47	340	1	283	1.0e-54	207	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
644990000	266	31.82	1	261	10	272	1.0e-42	167	COG3752	Steroid 5-alpha reductase family enzyme	272
644990002	438	39.58	143	425	6	283	3.0e-79	289	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
644990003	271	32.09	2	267	5	259	1.0e-48	186	COG3496	Uncharacterized conserved protein, DUF1365 family	261
644990004	420	39.23	1	413	9	421	6.0e-109	387	COG2907	Predicted NAD/FAD-binding protein	447
644990005	303	33.33	27	301	20	289	1.0e-47	183	COG1398	Fatty-acid desaturase	289
644990008	459	40.73	5	459	3	458	2.0e-120	425	COG0415	Deoxyribodipyrimidine photolyase	461
644990009	315	45.28	155	313	1	159	8.0e-47	180	COG3272	Uncharacterized conserved protein YbgA, DUF1722 family	163
644990011	160	50.65	6	159	1	150	1.0e-39	155	COG0782	Transcription elongation factor, GreA/GreB family	151
644990012	1074	68.59	13	410	1	395	0.0e+00	577	COG0458	Carbamoylphosphate synthase large subunit	400
644990013	388	61.83	16	387	3	366	0.0e+00	587	COG0505	Carbamoylphosphate synthase small subunit	368
644990014	267	49.62	1	265	2	266	6.0e-82	297	COG0289	Dihydrodipicolinate reductase	266
644990015	206	27.44	27	206	1	215	9.0e-17	80.3	COG2755	Lysophospholipase L1 or related esterase	216
644990016	665	34.32	24	625	3	620	1.0e-94	341	COG1297	Uncharacterized membrane protein, oligopeptide transporter (OPT) family	624
644990017	311	28.42	6	294	2	290	1.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
644990019	312	39.37	6	306	19	366	6.0e-53	201	COG3329	Uncharacterized conserved protein	372
644990020	165	57.42	7	161	2	154	2.0e-53	202	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
644990021	390	38.19	16	372	3	361	1.0e-94	340	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
644990022	375	61.97	1	372	1	371	0.0e+00	502	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
644990023	642	62.54	1	604	4	579	0.0e+00	675	COG0443	Molecular chaperone DnaK (HSP70)	579
644990026	238	39.83	5	237	7	238	3.0e-62	231	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
644990033	215	33.77	1	153	3	147	1.0e-27	116	COG3758	Various environmental stresses-induced protein Ves (function unknown)	193
644990034	207	42.79	1	207	1	191	5.0e-29	120	COG0576	Molecular chaperone GrpE (heat shock protein)	193
644990035	342	38.19	1	340	1	342	2.0e-80	293	COG1420	Transcriptional regulator of heat shock response	346
644990036	291	42.55	10	289	3	281	1.0e-73	269	COG0061	NAD kinase	281
644990037	552	45.42	1	552	1	555	0.0e+00	529	COG0497	DNA repair ATPase RecN	557
644990039	268	35.4	2	268	1	255	2.0e-15	76.2	COG0730	Uncharacterized membrane protein YfcA	258
644990040	264	48.01	1	263	6	280	8.0e-64	237	COG0682	Prolipoprotein diacylglyceryltransferase	287
644990041	264	70.68	1	264	3	268	4.0e-120	424	COG0207	Thymidylate synthase	268
644990042	171	45.93	6	169	1	167	2.0e-39	155	COG0262	Dihydrofolate reductase	167
644990043	199	26.34	8	199	2	199	2.0e-18	86.2	COG3764	Sortase (surface protein transpeptidase)	210
644990045	132	32.12	1	132	1	137	6.0e-23	99.6	COG3304	Uncharacterized membrane protein YccF, DUF307 family	145
644990046	169	24.5	5	148	6	156	4.0e-14	71.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644990047	325	33.02	5	324	1	310	1.0e-57	216	COG0039	Malate/lactate dehydrogenase	313
644990048	700	50.59	16	693	11	677	0.0e+00	814	COG1200	RecG-like helicase	677
644990049	305	29.76	1	287	1	281	4.0e-40	159	COG0583	DNA-binding transcriptional regulator, LysR family	297
644990051	407	37.62	3	406	2	390	7.0e-67	248	COG2311	Uncharacterized membrane protein YeiB	394
644990053	128	46.51	1	127	2	130	1.0e-30	125	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
644990054	705	42.88	4	703	6	700	0.0e+00	832	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
644990055	82	45.71	1	69	1	70	8.0e-12	61.9	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
644990056	217	56.45	11	196	2	186	1.0e-74	272	COG0194	Guanylate kinase	191
644990057	288	49.31	1	288	1	290	1.0e-82	299	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
644990058	269	18.92	158	263	45	155	7.0e-06	44.6	COG0639	Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family	155
644990059	125	56	1	125	2	126	1.0e-42	165	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
644990060	260	60.56	1	250	1	246	2.0e-93	335	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
644990061	142	35.82	5	138	6	137	1.0e-19	88.9	COG5331	Uncharacterized protein	139
644990062	160	46.58	1	160	1	161	3.0e-37	147	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
644990063	238	59.24	1	237	8	230	7.0e-80	290	COG0689	Ribonuclease PH	230
644990066	598	21.32	214	543	54	328	9.0e-15	75.8	COG5276	Uncharacterized conserved protein	370
644990068	397	53	1	395	14	406	0.0e+00	464	COG0281	Malic enzyme	432
644990070	506	27.2	21	477	10	477	9.0e-86	311	COG0069	Glutamate synthase domain 2	485
644990071	210	27.23	8	208	1	182	3.0e-22	98.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644990073	106	30.63	1	106	11	121	6.0e-16	75.8	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
644990074	133	47.2	4	128	10	133	5.0e-31	126	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
644990076	223	20.98	13	151	17	150	2.0e-10	59.6	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
644990077	223	53.74	8	221	13	226	3.0e-69	254	COG3066	DNA mismatch repair protein MutH	229
644990082	961	51.33	15	450	1	449	0.0e+00	576	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
644990082	961	59.51	452	930	9	496	0.0e+00	711	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
644990083	129	58.46	1	129	2	131	1.0e-41	161	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
644990084	362	45.62	1	359	4	374	1.0e-107	383	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
644990085	153	29.84	31	152	33	153	3.0e-16	78	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
644990086	548	33.09	16	547	1	533	5.0e-85	308	COG1178	ABC-type Fe3+ transport system, permease component	540
644990087	359	23.93	64	357	1	297	8.0e-40	157	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
644990088	98	20	1	93	1	100	2.0e-09	53.8	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
644990090	397	33.59	6	397	1	385	1.0e-74	274	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
644990093	412	36.07	2	400	1	385	4.0e-75	275	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
644990094	438	32.56	6	430	10	384	1.0e-73	271	COG0006	Xaa-Pro aminopeptidase	384
644990095	183	30.9	3	178	8	182	4.0e-22	97.7	COG3079	Uncharacterized conserved protein YgfB, UPF0149 family	186
644990097	108	37.76	6	103	1	98	2.0e-14	71.1	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
644990099	212	33.85	5	196	2	190	3.0e-35	141	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
644990100	154	61.04	1	154	2	152	6.0e-57	212	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
644990101	219	54.63	1	219	1	227	8.0e-74	270	COG0120	Ribose 5-phosphate isomerase	227
644990104	451	44.03	4	450	2	457	1.0e-127	450	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644990105	665	17.48	387	658	46	327	2.0e-15	78.3	COG0642	Signal transduction histidine kinase	336
644990107	409	41.99	8	335	1	323	2.0e-87	316	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
644990108	354	46.36	1	329	1	286	6.0e-101	361	COG0191	Fructose/tagatose bisphosphate aldolase	286
644990109	392	56.22	1	391	2	395	0.0e+00	482	COG0126	3-phosphoglycerate kinase	395
644990110	333	57.36	2	330	1	330	2.0e-123	435	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
644990111	672	62.69	13	672	8	663	0.0e+00	1065	COG0021	Transketolase	663
644990113	218	61.11	1	216	1	215	7.0e-83	299	COG3155	Enhancing lycopene biosynthesis protein 2	217
644990114	693	35.65	6	691	5	664	0.0e+00	486	COG1331	Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains	667
644990115	242	35.19	5	234	1	233	3.0e-52	198	COG3821	Uncharacterized membrane protein	234
644990117	205	41.94	1	123	2	119	6.0e-20	90.8	COG2863	Cytochrome c553	121
644990118	207	49.74	1	194	2	196	8.0e-65	240	COG0218	GTP-binding protein EngB required for normal cell division	200
644990121	915	58.97	316	915	1	593	0.0e+00	772	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
644990122	496	51.79	1	496	1	494	0.0e+00	658	COG3517	Predicted component of the type VI protein secretion system	495
644990123	172	44.38	1	169	1	169	1.0e-44	172	COG3516	Predicted component of the type VI protein secretion system	169
644990124	358	25.77	8	352	9	344	1.0e-15	77.4	COG3515	Predicted component of the type VI protein secretion system	346
644990125	275	36.55	14	252	7	254	5.0e-46	178	COG0631	Serine/threonine protein phosphatase PrpC	262
644990126	266	26.47	7	238	7	216	1.0e-19	90.6	COG3913	Uncharacterized protein	227
644990127	1183	32.36	11	1183	8	1187	0.0e+00	750	COG3523	Type VI protein secretion system component VasK	1188
644990128	439	34.23	11	268	1	260	6.0e-46	178	COG3455	Type VI protein secretion system component VasF	262
644990129	447	38.74	2	444	4	446	3.0e-100	359	COG3522	Predicted component of the type VI protein secretion system	446
644990130	153	24.63	4	136	1	134	2.0e-16	78.4	COG3521	Predicted component of the type VI protein secretion system	159
644990131	466	28.67	4	460	3	424	1.0e-55	211	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
644990132	695	21.04	69	447	2	372	6.0e-26	112	COG0515	Serine/threonine protein kinase	384
644990133	293	21.3	7	271	44	305	5.0e-25	108	COG2988	Succinylglutamate desuccinylase	324
644990135	436	25.9	21	269	6	250	5.0e-25	109	COG2966	Uncharacterized membrane protein YjjP, DUF1212 family	250
644990137	770	19.39	91	770	42	768	3.0e-27	117	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644990138	162	30.67	1	161	1	160	5.0e-15	73.9	COG5472	Predicted small integral membrane protein	164
644990140	591	20.59	87	591	28	458	6.0e-26	112	COG0471	Di- and tricarboxylate transporter	461
644990141	310	47.28	1	293	1	293	2.0e-73	268	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
644990142	153	30.82	8	152	6	136	7.0e-19	86.6	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
644990143	147	41.23	29	142	19	121	4.0e-24	103	COG3245	Cytochrome c5	126
644990145	390	43.02	18	359	1	337	2.0e-87	316	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
644990146	225	29.11	13	222	13	225	6.0e-14	71.1	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
644990147	135	22.3	1	133	8	148	4.0e-12	63.9	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
644990157	1068	25.12	662	1047	12	400	2.0e-36	148	COG1228	Imidazolonepropionase or related amidohydrolase	406
644990158	624	36.72	446	621	5	180	2.0e-37	150	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644990159	158	50	4	157	3	156	8.0e-47	179	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
644990160	84	41.1	10	81	5	77	1.0e-18	84.9	COG0425	TusA-related sulfurtransferase	78
644990161	197	44.33	3	195	2	195	2.0e-56	212	COG3816	Uncharacterized protein	205
644990164	182	58.89	3	180	2	181	2.0e-71	262	COG2818	3-methyladenine DNA glycosylase Tag	188
644990165	308	78.52	1	298	1	298	0.0e+00	555	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
644990166	690	50.94	1	690	1	691	0.0e+00	804	COG0751	Glycyl-tRNA synthetase, beta subunit	691
644990167	182	39.87	10	166	6	163	2.0e-41	161	COG0241	Histidinol phosphatase or a related phosphatase	181
644990168	264	20.24	8	218	4	248	1.0e-08	53.8	COG0451	Nucleoside-diphosphate-sugar epimerase	314
644990169	244	32.11	36	244	52	262	5.0e-26	111	COG3137	Putative salt-induced outer membrane protein YdiY	262
644990170	178	48.3	1	176	2	170	8.0e-56	209	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
644990173	342	30.63	65	342	20	298	2.0e-39	156	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
644990175	454	38.6	6	454	3	454	2.0e-118	419	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
644990177	132	34.92	2	123	3	128	3.0e-25	107	COG0615	Glycerol-3-phosphate cytidylyltransferase, cytidylyltransferase family	140
644990178	270	20.08	11	264	5	266	2.0e-14	72.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
644990179	681	52.72	1	679	8	681	0.0e+00	882	COG0339	Zn-dependent oligopeptidase	683
644990180	513	30.49	1	510	1	502	2.0e-98	353	COG1070	Sugar (pentulose or hexulose) kinase	502
644990182	202	21.69	1	189	2	184	1.0e-13	70.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644990184	833	19.42	8	822	4	720	3.0e-60	227	COG1033	Predicted exporter protein, RND superfamily	727
644990186	188	42.47	5	188	11	196	1.0e-44	172	COG3310	Uncharacterized protein	196
644990187	240	20.52	1	240	4	266	7.0e-11	61.1	COG0428	Zinc transporter ZupT	266
644990188	199	28.93	1	193	7	202	3.0e-40	158	COG1573	Uracil-DNA glycosylase	202
644990189	282	33.07	37	271	24	278	6.0e-40	157	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644990192	203	45.36	25	200	1	183	1.0e-51	196	COG0742	16S rRNA G966 N2-methylase RsmD	187
644990193	427	52.68	94	420	5	340	1.0e-110	393	COG0552	Signal recognition particle GTPase	340
644990194	227	61.19	1	219	1	219	1.0e-90	325	COG2884	ABC-type ATPase involved in cell division	223
644990195	322	35.22	21	321	1	296	6.0e-55	208	COG2177	Cell division protein FtsX	297
644990196	192	45.26	1	189	3	188	1.0e-44	173	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
644990197	283	34.39	5	283	57	332	2.0e-65	242	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
644990198	264	21.93	1	263	4	262	2.0e-17	83.5	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644990202	85	33.33	5	82	1	78	4.0e-07	46.5	COG0236	Acyl carrier protein	80
644990203	188	35.8	12	184	15	190	4.0e-26	111	COG4648	Uncharacterized membrane protein	201
644990204	447	22.75	91	447	132	520	1.0e-21	97.7	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
644990205	124	17.12	6	115	25	133	1.0e-05	42.1	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
644990206	578	43.87	253	561	2	306	4.0e-85	309	COG4261	Predicted acyltransferase, LPLAT superfamily	309
644990207	516	36.96	8	511	4	496	2.0e-128	452	COG2986	Histidine ammonia-lyase	498
644990208	149	26.87	16	148	7	137	2.0e-20	91.9	COG0824	Acyl-CoA thioesterase FadM	137
644990210	787	27.11	10	774	16	779	2.0e-86	314	COG4258	Predicted exporter	788
644990211	433	20.75	7	430	3	390	2.0e-33	137	COG0644	Dehydrogenase (flavoprotein)	396
644990213	396	30.43	3	395	1	410	1.0e-68	253	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644990214	162	35.29	20	137	12	130	2.0e-19	88.9	COG4706	Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain	161
644990215	241	40.08	1	241	4	251	4.0e-44	171	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644990216	405	38.59	1	405	2	411	1.0e-104	373	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644990217	249	33.05	7	240	1	227	6.0e-39	154	COG0543	NAD(P)H-flavin reductase	252
644990218	493	59.22	1	488	1	476	0.0e+00	676	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
644990220	418	77.51	1	418	4	420	0.0e+00	717	COG1158	Transcription termination factor Rho	422
644990222	420	44.82	1	381	21	399	4.0e-100	358	COG0513	Superfamily II DNA and RNA helicase	513
644990225	165	40.91	1	154	3	156	1.0e-28	119	COG1607	Acyl-CoA hydrolase	157
644990226	295	25.81	8	283	8	273	4.0e-33	135	COG4757	Predicted alpha/beta hydrolase	281
644990229	164	22.08	1	151	7	159	2.0e-09	55.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
644990230	176	55.43	2	176	1	170	2.0e-51	194	COG4675	Microcystin-dependent protein  (function unknown)	170
644990231	173	50	2	172	1	169	2.0e-51	194	COG4675	Microcystin-dependent protein  (function unknown)	170
644990232	168	48.82	2	168	1	170	1.0e-46	179	COG4675	Microcystin-dependent protein  (function unknown)	170
644990236	295	31.39	1	295	3	309	2.0e-23	103	COG0679	Predicted permease	311
644990237	332	61.77	6	332	5	329	0.0e+00	519	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
644990238	308	62.88	9	306	10	303	2.0e-127	448	COG0408	Coproporphyrinogen III oxidase	303
644990239	187	39.04	6	187	13	196	1.0e-38	153	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
644990240	168	53.46	6	164	5	161	8.0e-44	169	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
644990241	276	30.63	143	251	18	127	3.0e-10	59.1	COG0526	Thiol-disulfide isomerase or thioredoxin	127
644990242	159	36	5	152	1	147	6.0e-23	100	COG2922	Uncharacterized conserved protein Smg, DUF494 family	157
644990243	363	39.01	1	363	1	350	4.0e-87	314	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
644990245	175	57.14	1	164	1	168	6.0e-57	213	COG0242	Peptide deformylase	168
644990246	319	52.84	4	302	1	299	8.0e-112	396	COG0223	Methionyl-tRNA formyltransferase	307
644990247	443	38.48	100	442	1	355	6.0e-80	291	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
644990248	457	38.96	1	229	1	225	3.0e-46	180	COG0569	Trk K+ transport system, NAD-binding component	225
644990249	482	46.57	1	482	1	488	7.0e-99	354	COG0168	Trk-type K+ transport system, membrane component	499
644990250	301	29.87	12	300	16	308	2.0e-54	206	COG1560	Lauroyl/myristoyl acyltransferase	308
644990252	609	54.83	1	609	1	597	0.0e+00	790	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
644990253	462	57.08	1	453	1	459	0.0e+00	608	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
644990254	141	45.74	4	131	3	131	5.0e-27	113	COG0355	FoF1-type ATP synthase, epsilon subunit	135
644990255	458	76.99	1	458	1	465	0.0e+00	823	COG0055	FoF1-type ATP synthase, beta subunit	468
644990256	286	52.8	5	286	1	286	2.0e-98	352	COG0224	FoF1-type ATP synthase, gamma subunit	287
644990257	515	67.45	3	515	1	502	0.0e+00	823	COG0056	FoF1-type ATP synthase, alpha subunit	504
644990258	178	45.2	1	176	1	177	4.0e-39	154	COG0712	FoF1-type ATP synthase, delta subunit	178
644990259	156	43.31	1	156	2	158	2.0e-19	88.8	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
644990260	88	38.46	1	78	2	79	3.0e-06	43.7	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
644990261	282	41.84	1	282	1	246	6.0e-51	194	COG0356	FoF1-type ATP synthase, membrane subunit a	246
644990262	126	31.15	4	124	3	124	1.0e-08	52.2	COG3312	FoF1-type ATP synthase assembly protein I	128
644990263	298	39.76	38	289	1	240	3.0e-33	135	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
644990264	258	41.73	1	252	1	253	3.0e-61	228	COG1192	Cellulose biosynthesis protein BcsQ	259
644990265	214	34.58	8	214	1	214	2.0e-47	182	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
644990266	628	65.44	3	626	1	621	0.0e+00	996	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
644990269	453	27.54	40	436	10	403	3.0e-42	166	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
644990270	452	49.78	1	452	1	454	0.0e+00	529	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
644990271	536	44.95	241	536	5	306	1.0e-69	257	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
644990272	74	57.75	1	71	5	75	4.0e-28	116	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
644990273	128	42.34	15	125	1	111	4.0e-19	86.9	COG0594	RNase P protein component	117
645946644	167	25	1	163	18	185	1.0e-13	69.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
645946645	263	21.71	1	263	4	305	8.0e-16	77.5	COG0385	Predicted Na+-dependent transporter	319
645946654	244	45.93	6	244	4	242	5.0e-72	264	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
645946655	211	28.28	24	209	14	211	2.0e-19	89.5	COG0625	Glutathione S-transferase	211
