gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
644107475	309	35.53	1	303	12	302	2.0e-65	242	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
644107476	296	41.67	8	270	4	263	7.0e-39	154	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
644107477	241	38.5	5	222	4	229	1.0e-63	236	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
644107479	381	25	241	379	3	146	8.0e-19	88.5	COG4639	Predicted kinase	168
644107482	354	30.74	94	345	9	252	1.0e-36	147	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
644107483	366	23.79	16	365	36	421	2.0e-20	93.7	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
644107485	244	24.37	4	119	1	119	1.0e-13	70.5	COG0789	DNA-binding transcriptional regulator, MerR family	124
644107486	406	31.39	173	389	18	239	3.0e-42	166	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644107492	195	56.54	3	193	1	190	3.0e-75	274	COG0193	Peptidyl-tRNA hydrolase	190
644107495	315	59.81	1	314	2	314	2.0e-122	431	COG0462	Phosphoribosylpyrophosphate synthetase	314
644107496	290	51.03	8	285	5	289	2.0e-92	332	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
644107497	231	49.76	25	231	1	206	5.0e-58	217	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
644107498	418	51.67	1	418	1	412	0.0e+00	468	COG0373	Glutamyl-tRNA reductase	414
644107499	360	69.7	1	359	1	363	0.0e+00	564	COG0216	Protein chain release factor A	363
644107500	281	46.59	1	277	1	278	4.0e-78	284	COG2890	Methylase of polypeptide chain release factors	280
644107501	133	56.59	5	132	1	129	5.0e-30	123	COG3094	Uncharacterized membrane protein SirB2	129
644107502	269	52.04	1	269	2	269	7.0e-82	297	COG2912	Regulator of sirC expression, contains transglutaminase-like and TPR domains	269
644107503	284	69.04	2	282	1	279	0.0e+00	480	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
644107504	514	50.93	29	503	12	493	0.0e+00	620	COG0753	Catalase	496
644107507	509	63.19	2	365	1	356	0.0e+00	466	COG3288	NAD/NADP transhydrogenase alpha subunit	356
644107508	462	58.91	1	462	1	463	0.0e+00	639	COG1282	NAD/NADP transhydrogenase beta subunit	463
644107509	317	24.68	155	303	7	154	1.0e-11	63.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
644107510	248	35.92	31	235	7	212	2.0e-38	153	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
644107511	175	41.32	3	167	1	167	1.0e-45	175	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
644107513	439	24.83	1	436	2	432	2.0e-41	164	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
644107514	174	54.55	1	174	6	179	5.0e-47	180	COG2032	Cu/Zn superoxide dismutase	179
644107515	409	45.14	121	408	1	283	2.0e-80	293	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
644107516	241	37.7	3	235	7	249	2.0e-55	209	COG3496	Uncharacterized conserved protein, DUF1365 family	261
644107519	820	42.21	17	819	9	820	0.0e+00	766	COG4458	Uncharacterized protein	821
644107520	995	58.74	1	995	1	1014	0.0e+00	1405	COG4457	Uncharacterized protein	1014
644107522	229	52.17	1	229	1	230	9.0e-71	259	COG4305	Peptidoglycan-binding domain, expansin	232
644107523	142	38.62	4	142	1	143	3.0e-30	124	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
644107524	131	33	31	130	1	100	5.0e-10	56.9	COG3783	Soluble cytochrome b562	100
644107525	184	30.68	7	182	6	181	5.0e-20	90.9	COG3226	DNA-binding transcriptional regulator YbjK	204
644107526	398	21.86	15	327	21	349	4.0e-15	76	COG0738	Fucose permease	422
644107528	657	35.04	301	645	42	408	3.0e-50	194	COG0840	Methyl-accepting chemotaxis protein	408
644107529	293	22.33	3	293	1	297	4.0e-22	98.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
644107531	111	30.84	3	108	5	109	8.0e-15	72.4	COG4538	Uncharacterized protein	112
644107532	130	25	16	126	12	116	1.0e-06	45.4	COG4994	Uncharacterized protein	120
644107543	385	41.18	1	384	47	406	3.0e-95	342	COG1649	Uncharacterized lipoprotein YddW, UPF0748 family	418
644107546	460	47.2	30	455	27	446	0.0e+00	485	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
644107547	498	30.37	37	492	5	447	2.0e-87	316	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
644107549	76	30.77	1	52	1	52	9.0e-09	51.9	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
644107553	284	39.34	1	266	1	270	4.0e-51	195	COG3769	Predicted mannosyl-3-phosphoglycerate phosphatase, HAD superfamily	274
644107555	394	30.26	48	388	14	351	2.0e-56	213	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
644107556	249	57.5	2	240	8	246	1.0e-87	315	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
644107560	495	19.11	17	418	13	360	8.0e-15	75.6	COG2814	Predicted arabinose efflux permease, MFS family	394
644107561	221	51.77	1	221	1	223	5.0e-61	227	COG0132	Dethiobiotin synthetase	223
644107562	405	27.83	80	405	1	314	4.0e-52	199	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
644107563	298	34.01	3	296	1	288	1.0e-37	150	COG0583	DNA-binding transcriptional regulator, LysR family	297
644107564	422	25	42	417	9	384	4.0e-26	112	COG2814	Predicted arabinose efflux permease, MFS family	394
644107566	465	69.41	2	462	1	461	0.0e+00	797	COG0114	Fumarate hydratase class II	462
644107568	519	33.06	3	491	1	471	5.0e-77	282	COG5339	Uncharacterized conserved protein YdgA, DUF945 family	479
644107569	325	21.17	4	315	8	332	4.0e-22	99.1	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
644107570	338	40.65	1	334	6	341	2.0e-88	319	COG1816	Adenosine deaminase	345
644107571	154	53.33	18	152	23	153	8.0e-44	169	COG4875	Uncharacterized protein	156
644107572	330	39.82	1	329	1	316	8.0e-66	244	COG0385	Predicted Na+-dependent transporter	319
644107573	348	30.14	4	347	3	342	3.0e-51	195	COG0673	Predicted dehydrogenase	342
644107574	310	29.37	165	290	2	127	1.0e-22	100	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644107575	313	40.45	1	311	2	314	7.0e-57	214	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
644107576	507	49.6	1	496	2	498	0.0e+00	628	COG1129	ABC-type sugar transport system, ATPase component	500
644107577	327	24.31	5	325	13	320	7.0e-31	128	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
644107578	561	41.83	5	557	3	533	0.0e+00	597	COG1069	Ribulose kinase	544
644107579	501	68.47	1	498	1	495	0.0e+00	754	COG2160	L-arabinose isomerase	497
644107581	193	79.79	1	193	1	193	1.0e-66	245	COG4657	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfA subunit	193
644107582	192	67.71	1	192	1	192	6.0e-69	253	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
644107583	753	59.62	11	536	1	528	0.0e+00	651	COG4656	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfC subunit	529
644107584	351	63.22	2	349	1	335	3.0e-113	401	COG4658	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfD subunit	338
644107585	209	62.05	3	197	2	195	1.0e-70	259	COG4659	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit	195
644107586	235	79.25	1	212	1	212	1.0e-87	316	COG4660	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfE subunit	212
644107587	211	56.87	1	211	1	211	1.0e-85	309	COG0177	Endonuclease III	211
644107588	490	45.29	1	476	14	497	1.0e-129	456	COG3104	Dipeptide/tripeptide permease	498
644107589	324	27.33	1	298	1	294	1.0e-38	153	COG0583	DNA-binding transcriptional regulator, LysR family	297
644107590	866	48.17	3	594	1	569	0.0e+00	679	COG0550	DNA topoisomerase IA	570
644107592	348	32.27	40	341	8	310	2.0e-58	219	COG0616	Periplasmic serine protease, ClpP class	317
644107593	253	30.56	10	247	3	250	1.0e-42	166	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644107594	196	57.58	1	196	1	198	5.0e-76	277	COG2109	ATP:corrinoid adenosyltransferase	198
644107595	294	48.02	1	247	1	248	4.0e-72	265	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
644107596	206	46.83	2	205	1	204	1.0e-60	225	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
644107597	294	50	13	268	3	254	3.0e-66	245	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
644107598	520	42.97	10	518	2	462	0.0e+00	467	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
644107599	192	50	1	190	1	191	6.0e-65	240	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
644107600	332	49.7	1	330	4	334	3.0e-105	375	COG0547	Anthranilate phosphoribosyltransferase	338
644107601	455	53.75	6	254	1	253	4.0e-88	318	COG0134	Indole-3-glycerol phosphate synthase	254
644107602	396	68.43	1	396	2	396	0.0e+00	697	COG0133	Tryptophan synthase beta chain	396
644107603	268	49.25	1	268	1	265	2.0e-91	328	COG0159	Tryptophan synthase alpha chain	265
644107605	210	60.83	1	210	1	213	1.0e-65	242	COG3047	Outer membrane protein W	213
644107607	189	61.11	1	180	1	180	3.0e-60	224	COG2917	Intracellular septation protein A	180
644107608	140	57.69	1	130	3	129	6.0e-46	176	COG1607	Acyl-CoA hydrolase	157
644107609	252	35.09	10	235	1	228	2.0e-17	82.9	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
644107610	98	54.08	1	98	1	92	2.0e-22	97.3	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
644107611	557	27.06	180	531	32	406	4.0e-34	140	COG0840	Methyl-accepting chemotaxis protein	408
644107612	486	37.83	47	486	1	438	5.0e-88	318	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
644107613	107	77.57	1	107	2	108	4.0e-39	153	COG3099	Uncharacterized conserved protein YciU, UPF0263 family	108
644107614	344	47.6	7	319	1	262	2.0e-98	352	COG4608	ABC-type oligopeptide transport system, ATPase component	309
644107615	331	58.81	13	326	1	315	2.0e-129	455	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
644107616	302	41.81	17	302	2	287	3.0e-69	255	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644107617	306	43.35	1	306	1	315	1.0e-84	306	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644107618	545	41.61	6	544	3	562	1.0e-128	453	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
644107619	556	41.89	16	555	2	562	3.0e-130	459	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
644107620	891	48.06	451	862	1	377	9.0e-125	441	COG1454	Alcohol dehydrogenase, class IV	377
644107621	168	53.89	1	166	33	199	6.0e-61	226	COG1435	Thymidine kinase	201
644107622	135	63.57	7	135	1	127	7.0e-32	129	COG2916	DNA-binding protein H-NS	128
644107623	303	57.53	5	301	1	291	9.0e-116	409	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
644107624	338	40.32	3	124	1	124	2.0e-19	89.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
644107625	301	35.46	1	301	7	295	2.0e-54	206	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
644107626	155	49.68	1	155	1	151	2.0e-47	181	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
644107627	282	51.93	3	282	2	286	1.0e-110	393	COG0788	Formyltetrahydrofolate hydrolase	287
644107629	208	46.57	1	203	5	208	7.0e-52	196	COG2860	Uncharacterized membrane protein YeiH	209
644107630	268	47.04	1	268	1	261	2.0e-90	325	COG0708	Exonuclease III	261
644107632	641	34.58	1	609	1	557	0.0e+00	535	COG0550	DNA topoisomerase IA	570
644107633	183	28.43	1	182	3	204	3.0e-17	81.5	COG0778	Nitroreductase	207
644107634	616	37.78	272	582	4	317	1.0e-70	261	COG0616	Periplasmic serine protease, ClpP class	317
644107635	339	37.32	1	333	17	351	1.0e-84	306	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
644107636	215	31.65	1	214	4	205	1.0e-33	136	COG1335	Nicotinamidase-related amidase	205
644107637	92	70	1	89	1	90	2.0e-32	130	COG3139	Uncharacterized conserved protein YeaC, DUF1315 family	90
644107638	121	58.47	1	117	16	133	4.0e-49	186	COG0229	Peptide methionine sulfoxide reductase MsrB	140
644107639	331	67.27	2	331	1	332	0.0e+00	482	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
644107640	289	49.83	3	289	1	286	6.0e-90	324	COG0676	D-hexose-6-phosphate mutarotase	287
644107641	283	36.55	1	283	2	276	1.0e-73	269	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
644107642	242	41.8	1	242	15	258	2.0e-55	209	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
644107643	644	71.49	1	644	1	649	0.0e+00	923	COG2766	Predicted Ser/Thr protein kinase	649
644107644	424	70.52	1	423	1	421	0.0e+00	589	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
644107646	399	21.95	24	388	34	391	6.0e-15	75.6	COG2814	Predicted arabinose efflux permease, MFS family	394
644107647	417	32.48	1	417	5	383	1.0e-50	194	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644107648	249	31.02	6	244	88	330	1.0e-35	143	COG0205	6-phosphofructokinase	347
644107649	99	34.38	3	96	1	92	4.0e-13	66.4	COG3414	Phosphotransferase system, galactitol-specific IIB component	93
644107650	445	37.28	1	444	4	467	1.0e-79	290	COG3037	Ascorbate-specific PTS system EIIC-type component UlaA	481
644107652	145	27.08	7	145	5	146	3.0e-20	90.8	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
644107654	277	28.67	3	274	24	300	1.0e-66	246	COG3684	Tagatose-1,6-bisphosphate aldolase	306
644107655	519	73.79	20	515	3	492	0.0e+00	747	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
644107656	239	28.93	1	233	1	241	3.0e-36	145	COG2186	DNA-binding transcriptional regulator, FadR family	241
644107657	526	74.17	4	517	3	516	0.0e+00	776	COG3067	Na+/H+ antiporter NhaB	516
644107658	176	42.44	1	168	1	170	2.0e-29	122	COG1495	Disulfide bond formation protein DsbB	170
644107661	148	61.49	1	148	6	153	1.0e-58	218	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
644107662	218	42.92	1	209	37	253	1.0e-64	239	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
644107663	85	71.95	1	82	11	92	1.0e-30	124	COG3100	Uncharacterized conserved protein YcgL, UPF0745 family	103
644107664	228	49.78	6	227	1	217	3.0e-62	231	COG0850	Septum formation inhibitor MinC	219
644107665	270	75.93	1	270	1	269	6.0e-126	443	COG2894	Septum formation inhibitor-activating ATPase MinD	272
644107666	94	54.22	12	94	7	88	3.0e-24	103	COG0851	Septum formation topological specificity factor MinE	88
644107667	374	48.78	6	373	1	361	9.0e-105	373	COG0349	Ribonuclease D	361
644107668	561	39.53	13	550	1	522	0.0e+00	479	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644107669	207	53.4	17	206	4	191	5.0e-54	204	COG3065	Starvation-inducible outer membrane lipoprotein	191
644107670	233	44.3	4	228	2	219	2.0e-55	208	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
644107671	639	44.09	10	637	1	649	0.0e+00	542	COG1199	Rad3-related DNA helicase	654
644107672	114	33.06	1	114	8	128	6.0e-25	106	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
644107673	100	67.8	19	77	1	59	2.0e-12	64.3	COG3140	Uncharacterized conserved protein YoaH, UPF0181 family	60
644107674	480	41.1	28	476	7	461	0.0e+00	481	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
644107675	197	18.54	26	167	1	147	2.0e-06	46.1	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
644107676	454	51.79	171	450	2	262	3.0e-90	325	COG1760	L-serine deaminase	262
644107677	518	54.66	1	243	8	254	1.0e-72	267	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
644107678	322	62.89	161	319	1	159	7.0e-58	217	COG3444	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB	159
644107679	265	55.85	2	265	1	264	3.0e-69	255	COG3715	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC	265
644107680	280	56.93	5	278	2	269	8.0e-108	383	COG3716	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID	269
644107681	152	61.18	1	152	1	152	1.0e-45	175	COG4811	Uncharacterized membrane protein YobD, UPF0266 family	152
644107682	190	52.63	1	188	1	190	8.0e-46	176	COG1971	Putative Mn2+ efflux pump MntP	190
644107684	69	70.15	3	69	1	67	1.0e-24	104	COG1278	Cold shock protein, CspA family	67
644107685	304	40.47	8	304	6	303	6.0e-85	307	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
644107686	296	49.4	10	260	5	254	1.0e-87	316	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
644107687	287	41.97	1	273	1	274	6.0e-51	194	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
644107688	285	44.7	3	265	1	264	5.0e-55	208	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
644107689	286	64.79	1	284	1	284	9.0e-118	416	COG3001	Fructosamine-3-kinase	286
644107691	221	35.94	7	217	2	214	8.0e-42	163	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
644107694	253	38.04	6	251	1	251	1.0e-47	183	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644107696	296	43.86	4	284	8	290	6.0e-54	204	COG1175	ABC-type sugar transport system, permease component	295
644107697	301	36.4	20	300	1	281	4.0e-62	231	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
644107698	375	47.55	1	368	1	338	4.0e-116	411	COG3839	ABC-type sugar transport system, ATPase component	338
644107699	430	26.85	1	427	5	432	4.0e-45	175	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
644107701	317	21.9	1	309	3	307	2.0e-23	103	COG0657	Acetyl esterase/lipase	312
644107702	191	34.34	1	161	1	159	1.0e-21	96.7	COG1988	Membrane-bound metal-dependent hydrolase YbcI, DUF457 family	190
644107703	464	73.64	1	459	2	458	0.0e+00	586	COG1823	L-cystine uptake protein TcyP, sodium:dicarboxylate symporter family	458
644107705	274	44.4	16	274	2	262	3.0e-77	282	COG0171	NH3-dependent NAD+ synthetase	268
644107707	572	44.31	1	571	3	567	0.0e+00	493	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
644107709	98	50.54	2	94	1	93	3.0e-28	116	COG0776	Bacterial nucleoid DNA-binding protein	94
644107710	795	49.62	143	794	1	650	0.0e+00	726	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
644107711	327	59.16	1	325	3	335	0.0e+00	464	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
644107712	118	83.05	1	118	1	118	3.0e-40	156	COG0292	Ribosomal protein L20	118
644107713	65	67.69	1	65	1	65	3.0e-12	63.3	COG0291	Ribosomal protein L35	65
644107715	642	54.84	34	641	1	589	0.0e+00	807	COG0441	Threonyl-tRNA synthetase	589
644107716	466	54.63	10	461	4	457	0.0e+00	528	COG1113	L-asparagine transporter and related permeases	462
644107718	263	44.31	14	258	1	246	1.0e-68	252	COG1414	DNA-binding transcriptional regulator, IclR family	246
644107719	388	18.11	1	367	58	407	1.0e-38	154	COG0823	Periplasmic component of the Tol biopolymer transport system	425
644107720	293	32.08	2	288	22	295	6.0e-45	174	COG0501	Zn-dependent protease with chaperone function	302
644107721	282	22.91	15	279	1	256	4.0e-24	105	COG0584	Glycerophosphoryl diester phosphodiesterase	257
644107722	445	25.34	1	435	3	431	2.0e-49	190	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
644107723	407	21.84	26	387	31	401	9.0e-08	51.8	COG2223	Nitrate/nitrite transporter NarK	417
644107724	249	37.6	1	249	2	243	3.0e-53	201	COG3279	DNA-binding response regulator, LytR/AlgR family	244
644107725	575	41.81	1	549	4	554	0.0e+00	579	COG3275	Sensor histidine kinase, LytS/YehU family	557
644107728	244	25	16	244	6	213	2.0e-24	105	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
644107729	116	33.33	7	113	32	132	3.0e-17	80.4	COG5566	Transcriptional regulator, Middle operon regulator (Mor) family	137
644107730	417	67.32	10	417	2	406	0.0e+00	616	COG0538	Isocitrate dehydrogenase	407
644107731	208	38.34	21	205	55	233	2.0e-43	168	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
644107732	148	22.96	4	136	9	143	6.0e-08	50.4	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
644107733	368	61.54	4	365	1	355	0.0e+00	506	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
644107734	212	71.98	2	208	1	206	8.0e-72	263	COG2915	Regulator of phage lambda lysogenization HflD, binds to CII and stimulates its degradation	207
644107735	456	35.09	12	456	1	436	5.0e-120	424	COG0015	Adenylosuccinate lyase	438
644107736	229	40.87	1	224	1	229	1.0e-54	206	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644107737	484	26.9	171	483	21	336	8.0e-33	135	COG0642	Signal transduction histidine kinase	336
644107738	373	60	1	373	9	383	0.0e+00	472	COG2850	Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain	383
644107739	410	47.82	1	405	4	412	7.0e-129	453	COG2195	Di- or tripeptidase	414
644107740	371	50.29	9	357	4	342	1.0e-115	409	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644107741	286	49.83	1	285	1	287	2.0e-67	249	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
644107742	258	46.48	4	258	10	265	8.0e-59	220	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
644107743	347	47.73	7	347	13	363	2.0e-88	319	COG0687	Spermidine/putrescine-binding periplasmic protein	363
644107744	210	31.55	1	206	22	174	1.0e-25	110	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
644107745	288	30.48	185	288	15	119	3.0e-11	62.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644107746	671	36	122	569	1	404	1.0e-94	341	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
644107747	257	56.81	1	257	1	208	1.0e-57	216	COG3109	sRNA-binding protein	208
644107748	168	59.09	1	154	10	163	2.0e-57	215	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
644107749	426	52.94	32	421	17	407	2.0e-128	453	COG2995	Uncharacterized paraquat-inducible protein A	418
644107750	879	46.68	1	569	1	553	0.0e+00	596	COG3008	Paraquat-inducible protein B	553
644107751	484	36.57	8	312	53	354	3.0e-73	269	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
644107753	223	35.02	15	223	90	300	4.0e-43	168	COG3921	Uncharacterized conserved protein	300
644107754	355	38.92	1	348	4	347	7.0e-74	270	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
644107757	70	68.66	4	70	1	67	4.0e-25	105	COG1278	Cold shock protein, CspA family	67
644107759	168	53.29	1	167	1	167	2.0e-58	218	COG1528	Ferritin	167
644107762	683	54.87	1	676	4	680	0.0e+00	903	COG1770	Protease II	682
644107763	392	71.57	1	392	1	394	0.0e+00	624	COG0027	Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	394
644107764	213	54.5	4	213	2	211	4.0e-64	237	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
644107765	491	55.97	5	489	3	482	0.0e+00	700	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
644107766	289	44.44	1	278	3	281	3.0e-71	261	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
644107767	480	51.35	2	479	1	477	0.0e+00	581	COG0469	Pyruvate kinase	477
644107768	323	36.27	11	315	2	307	2.0e-87	315	COG1560	Lauroyl/myristoyl acyltransferase	308
644107770	333	60	6	330	4	317	1.0e-118	419	COG4531	ABC-type Zn2+ transport system, periplasmic component/surface adhesin	318
644107771	252	47.06	1	236	1	254	2.0e-75	275	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
644107772	261	43.41	1	258	10	267	2.0e-45	175	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
644107773	319	30.74	3	296	2	306	3.0e-37	149	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644107774	442	36.19	8	432	4	430	2.0e-98	352	COG1455	Phosphotransferase system cellobiose-specific component IIC	432
644107775	114	41.18	13	114	1	102	1.0e-22	98.7	COG1447	Phosphotransferase system cellobiose-specific component IIA	105
644107776	459	22.3	75	459	24	429	2.0e-27	117	COG4580	Maltoporin (phage lambda and maltose receptor)	429
644107777	336	70.12	4	331	1	328	0.0e+00	546	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
644107778	205	48.56	1	205	1	201	2.0e-63	235	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
644107779	173	59.49	5	161	1	158	3.0e-58	217	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
644107780	247	61.57	1	241	1	241	1.0e-98	352	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
644107781	147	25.53	1	136	6	141	9.0e-10	56.1	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
644107782	598	63.28	1	586	1	585	0.0e+00	931	COG0173	Aspartyl-tRNA synthetase	585
644107783	405	39.85	1	405	1	404	6.0e-85	308	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
644107784	270	35.48	1	265	3	263	7.0e-47	180	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
644107785	131	67.72	1	127	5	131	1.0e-39	155	COG3788	Uncharacterized membrane protein YecN, MAPEG domain	131
644107788	252	49.39	1	243	1	240	3.0e-80	291	COG3142	Copper homeostasis protein CutC	241
644107789	182	57.39	3	178	10	185	7.0e-62	229	COG3102	Uncharacterized conserved protein YecM, predicted metalloenzyme	185
644107791	576	42.05	1	576	1	577	0.0e+00	638	COG0018	Arginyl-tRNA synthetase	577
644107792	511	54.58	1	510	7	518	0.0e+00	465	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
644107793	321	27.13	22	321	5	332	3.0e-42	165	COG0673	Predicted dehydrogenase	342
644107794	210	68.84	1	210	1	213	1.0e-74	272	COG3132	Uncharacterized conserved protein YceH, UPF0502 family	215
644107795	194	28.8	12	194	4	186	3.0e-27	115	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644107796	401	20	63	392	65	390	1.0e-10	61.8	COG2814	Predicted arabinose efflux permease, MFS family	394
644107797	215	65.12	1	215	1	215	4.0e-84	304	COG2999	Glutaredoxin 2	215
644107799	192	44.5	1	187	7	204	4.0e-36	144	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
644107800	245	30.42	2	235	1	237	2.0e-49	189	COG1387	Histidinol phosphatase or related hydrolase of the PHP family	237
644107801	449	49.1	1	444	34	471	0.0e+00	484	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644107802	559	49.36	1	535	6	539	0.0e+00	526	COG2303	Choline dehydrogenase or related flavoprotein	542
644107803	217	34.86	1	213	5	218	5.0e-44	170	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
644107804	172	37.34	13	168	1	147	1.0e-37	149	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
644107805	508	47.18	24	502	155	646	0.0e+00	489	COG1067	Predicted ATP-dependent protease	647
644107806	152	76.51	1	149	1	149	3.0e-53	200	COG3120	Macrodomain Ter protein organizer, MatP/YcbG family	149
644107807	361	25.62	150	352	1	190	1.0e-28	120	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
644107808	168	54.34	1	168	1	169	1.0e-42	166	COG5404	Cell division inhibitor SulA, prevents FtsZ ring assembly	169
644107809	206	35.9	6	121	5	121	5.0e-18	84.6	COG3070	Transcriptional regulator of competence genes, TfoX/Sxy family	121
644107810	711	36.57	9	701	3	658	7.0e-120	425	COG1289	Uncharacterized membrane protein YccC	674
644107811	148	71.03	1	145	1	144	4.0e-51	193	COG3304	Uncharacterized membrane protein YccF, DUF307 family	145
644107813	152	69.01	8	149	1	142	7.0e-63	232	COG1803	Methylglyoxal synthase	142
644107814	174	36.26	2	170	1	167	2.0e-26	112	COG3110	Uncharacterized conserved protein YccT, UPF0319 family	216
644107815	137	61.31	1	137	4	140	2.0e-49	187	COG1832	Predicted CoA-binding protein	140
644107816	102	41.51	1	102	10	114	5.0e-26	109	COG3785	Heat shock protein HspQ	116
644107817	92	49.46	1	92	1	92	2.0e-23	100	COG1254	Acylphosphatase	92
644107818	109	78.9	1	109	3	111	5.0e-48	182	COG2920	Sulfur relay (sulfurtransferase) protein, DsrC/TusE family	111
644107819	219	37.12	1	219	4	232	3.0e-28	118	COG0670	Integral membrane protein, interacts with FtsH	233
644107822	140	26.4	1	125	6	120	2.0e-08	51.6	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
644107823	174	24	3	140	7	181	2.0e-14	72.2	COG1335	Nicotinamidase-related amidase	205
644107825	142	34.23	1	142	4	151	9.0e-13	66.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
644107828	514	38.73	104	473	14	408	2.0e-42	167	COG0840	Methyl-accepting chemotaxis protein	408
644107829	507	25.11	35	491	2	429	1.0e-45	178	COG3182	Uncharacterized iron-regulated membrane protein	442
644107830	522	59.14	16	522	25	530	0.0e+00	740	COG3131	Periplasmic glucans biosynthesis protein	534
644107831	854	66.58	71	846	1	735	0.0e+00	1027	COG2943	Membrane glycosyltransferase	736
644107832	306	51.63	4	306	3	307	8.0e-91	327	COG1560	Lauroyl/myristoyl acyltransferase	308
644107833	364	44.51	1	341	3	336	3.0e-97	348	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
644107834	359	43.44	20	339	1	308	1.0e-101	363	COG1054	Predicted sulfurtransferase	308
644107835	192	46.91	2	192	1	192	5.0e-52	197	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
644107836	184	47.78	3	182	1	180	3.0e-45	174	COG3038	Cytochrome b561	181
644107840	347	65.7	4	347	1	344	0.0e+00	558	COG0418	Dihydroorotase	344
644107841	95	35	1	80	2	81	2.0e-14	70.8	COG1359	Quinol monooxygenase YgiN	100
644107842	1111	55.8	1	490	4	487	0.0e+00	566	COG1530	Ribonuclease G or E	487
644107843	318	42.47	8	303	1	288	6.0e-75	274	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644107844	194	39.18	1	193	2	193	9.0e-58	216	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
644107845	173	41.01	1	173	1	176	5.0e-34	137	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
644107846	56	50.88	1	56	1	57	6.0e-12	62.6	COG0333	Ribosomal protein L32	57
644107847	348	55.36	3	347	1	338	3.0e-125	441	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
644107848	317	58.88	1	317	2	322	1.0e-122	433	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
644107849	309	55.81	1	309	1	310	2.0e-107	382	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
644107850	244	46.64	1	241	1	250	2.0e-48	185	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644107851	78	64.1	1	78	3	80	2.0e-11	61.1	COG0236	Acyl carrier protein	80
644107852	401	57.57	1	401	12	411	0.0e+00	488	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644107853	265	31	1	261	3	272	5.0e-46	177	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
644107854	339	45.13	1	335	4	342	8.0e-111	393	COG1559	Cell division protein YceG, involved in septum cleavage	342
644107855	219	48.82	1	209	1	208	4.0e-60	224	COG0125	Thymidylate kinase	208
644107857	265	49.62	1	256	1	256	1.0e-80	292	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
644107858	477	39.81	1	396	1	392	6.0e-73	268	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
644107861	116	40.18	3	112	1	109	2.0e-25	107	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
644107862	126	39.13	12	126	9	123	2.0e-22	97.8	COG5633	Uncharacterized conserved protein YcfL	123
644107863	193	42.35	1	192	4	198	1.0e-43	169	COG3417	Outer membrane lipoprotein LpoB, binds and activates PBP1b	200
644107864	294	22.64	29	289	7	264	1.0e-23	103	COG0510	Thiamine kinase and related kinases	269
644107865	338	39.61	1	338	9	356	9.0e-83	300	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
644107866	180	51.83	1	180	1	189	1.0e-66	245	COG3150	Predicted esterase YcpF, UPF0227 family	191
644107867	434	41.13	3	423	1	405	1.0e-120	426	COG1252	NADH dehydrogenase, FAD-containing subunit	405
644107868	175	85.55	1	173	5	177	7.0e-72	262	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
644107869	397	39.28	11	395	6	392	6.0e-54	205	COG2814	Predicted arabinose efflux permease, MFS family	394
644107870	402	21.88	38	396	39	394	1.0e-07	51.7	COG2814	Predicted arabinose efflux permease, MFS family	394
644107871	196	25.67	1	184	2	188	9.0e-08	50.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644107872	450	21.41	1	449	6	418	2.0e-56	213	COG0443	Molecular chaperone DnaK (HSP70)	579
644107873	1149	55.84	12	1148	7	1139	0.0e+00	1521	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
644107874	400	41.61	1	400	1	408	5.0e-102	364	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
644107875	235	49.33	6	227	1	223	8.0e-78	283	COG1136	ABC-type lipoprotein export system, ATPase component	226
644107876	415	41.59	3	415	2	408	3.0e-107	382	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
644107877	304	32.8	1	301	7	306	4.0e-53	201	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
644107878	261	47.18	12	251	1	244	1.0e-74	272	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
644107879	238	26.29	16	223	1	212	2.0e-23	102	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
644107882	345	69.28	25	343	6	324	5.0e-104	371	COG4139	ABC-type cobalamin transport system, permease component	326
644107883	183	48.09	1	183	1	162	2.0e-61	228	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
644107884	258	51.19	6	257	1	248	1.0e-75	276	COG4138	ABC-type cobalamin transport system, ATPase component	248
644107885	151	48.2	19	149	59	197	4.0e-26	110	COG0791	Cell wall-associated hydrolase, NlpC family	197
644107886	338	42.11	9	248	9	248	7.0e-59	220	COG0095	Lipoate-protein ligase A	248
644107887	483	48.66	2	483	5	488	0.0e+00	615	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
644107888	265	55.64	12	265	4	259	4.0e-87	314	COG4559	ABC-type hemin transport system, ATPase component	259
644107889	334	44.88	8	333	5	334	3.0e-59	222	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
644107890	272	49.23	15	270	38	297	1.0e-68	253	COG4558	ABC-type hemin transport system, periplasmic component	300
644107891	349	58.65	4	343	8	344	3.0e-122	431	COG3720	Putative heme degradation protein	349
644107892	440	40.62	1	440	1	440	0.0e+00	513	COG1486	Alpha-galactosidase/6-phospho-beta-glucosidase, family 4 of glycosyl hydrolase	442
644107893	529	31.03	1	427	8	393	6.0e-53	202	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
644107894	237	40.18	2	225	8	231	4.0e-49	188	COG2188	DNA-binding transcriptional regulator, GntR family	236
644107895	591	41.37	43	554	1	494	1.0e-97	350	COG0366	Glycosidase	505
644107896	348	61.89	1	348	2	350	0.0e+00	567	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
644107897	273	50.71	1	273	2	273	9.0e-90	323	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
644107898	792	50.06	9	792	3	738	0.0e+00	757	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
644107899	347	40.52	1	344	2	337	6.0e-88	318	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
644107900	369	25.28	1	354	1	347	4.0e-30	125	COG0628	Predicted PurR-regulated permease PerM	355
644107901	1017	33.14	31	543	11	459	1.0e-80	295	COG0277	FAD/FMN-containing dehydrogenase	459
644107902	138	33.58	1	136	1	137	2.0e-29	121	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
644107904	123	46.79	16	123	2	110	6.0e-35	139	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
644107905	499	40.22	42	497	1	412	1.0e-120	427	COG0719	Fe-S cluster assembly scaffold protein SufB	412
644107906	248	61.45	1	248	3	247	1.0e-102	366	COG0396	Fe-S cluster assembly ATPase SufC	251
644107907	448	27.76	49	436	24	410	1.0e-76	280	COG0719	Fe-S cluster assembly scaffold protein SufB	412
644107908	407	50.61	1	404	1	405	0.0e+00	477	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
644107909	138	51.08	1	138	5	143	5.0e-46	176	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
644107910	340	35.15	1	238	1	232	4.0e-37	148	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
644107911	78	83.33	1	78	1	78	2.0e-19	87.4	COG4238	Outer membrane murein-binding lipoprotein Lpp	78
644107912	470	54.74	1	470	4	477	0.0e+00	579	COG0469	Pyruvate kinase	477
644107915	633	28.03	97	455	3	373	3.0e-63	237	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
644107915	633	49.01	484	633	5	155	2.0e-49	191	COG2190	Phosphotransferase system IIA component	156
644107916	464	48.71	4	462	3	456	0.0e+00	575	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
644107917	546	30.46	104	546	3	429	1.0e-84	308	COG4580	Maltoporin (phage lambda and maltose receptor)	429
644107918	394	25.62	79	394	5	297	1.0e-54	207	COG2382	Enterochelin esterase or related enzyme	299
644107919	337	23.01	40	249	3	227	2.0e-17	83.4	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
644107920	477	76.62	17	477	35	496	0.0e+00	736	COG3303	Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit	501
644107922	223	41.29	27	223	1	200	7.0e-56	210	COG0437	Fe-S-cluster-containing dehydrogenase component	203
644107923	320	55.97	5	319	3	304	1.0e-68	253	COG3301	Formate-dependent nitrite reductase, membrane component NrfD	305
644107924	624	44.62	3	622	1	641	0.0e+00	506	COG1138	Cytochrome c biogenesis factor	648
644107925	133	41.35	1	133	4	136	2.0e-37	147	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
644107926	285	33.21	17	285	5	281	3.0e-37	148	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
644107927	210	59.11	1	200	2	204	1.0e-68	252	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
644107928	218	65.14	1	218	4	221	4.0e-49	187	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
644107929	246	45.75	1	243	34	280	2.0e-45	175	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
644107930	73	63.64	4	69	2	67	8.0e-17	78.8	COG3114	Heme exporter protein D	67
644107931	160	59.72	1	144	1	138	1.0e-46	179	COG2332	Cytochrome c-type biogenesis protein CcmE	153
644107932	651	60.09	1	648	1	648	0.0e+00	712	COG1138	Cytochrome c biogenesis factor	648
644107933	185	31.54	34	159	1	127	4.0e-13	68	COG0526	Thiol-disulfide isomerase or thioredoxin	127
644107934	152	46.67	1	145	1	150	2.0e-41	161	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
644107935	289	31.19	2	289	1	286	1.0e-42	166	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
644107936	200	64.21	10	199	1	189	2.0e-77	281	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
644107940	828	31.79	2	828	1	764	0.0e+00	589	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
644107941	106	48.15	1	81	2	81	2.0e-15	74.2	COG3062	Cytoplasmic chaperone NapD for the signal peptide of periplasmic nitrate reductase NapAB	94
644107943	572	45.6	2	554	1	566	0.0e+00	556	COG3850	Signal transduction histidine kinase, nitrate/nitrite-specific	574
644107944	210	47.32	7	206	1	205	3.0e-48	184	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644107945	320	28.66	1	320	5	310	4.0e-29	122	COG0679	Predicted permease	311
644107946	295	29.3	13	272	1	269	4.0e-27	115	COG0583	DNA-binding transcriptional regulator, LysR family	297
644107949	104	47.12	1	104	2	105	1.0e-17	81.3	COG2076	Multidrug transporter EmrE and related cation transporters	106
644107950	263	27.38	1	262	2	261	4.0e-33	135	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
644107951	257	36.9	7	257	2	253	5.0e-55	208	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
644107952	421	32.06	149	419	1	284	3.0e-32	132	COG1408	Predicted phosphohydrolase, MPP superfamily	284
644107953	724	67.26	1	723	7	730	0.0e+00	1153	COG0376	Catalase (peroxidase I)	730
644107955	153	27.27	23	131	17	126	1.0e-09	55.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
644107956	284	31.77	1	271	1	275	5.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
644107957	68	46.27	1	67	1	65	4.0e-15	73	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
644107958	232	37.23	1	231	1	230	1.0e-56	213	COG1794	Aspartate/glutamate racemase	230
644107959	231	41.99	1	231	1	218	2.0e-53	202	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
644107960	478	58.96	4	464	1	459	0.0e+00	648	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
644107962	517	35.19	4	515	3	519	4.0e-89	322	COG1620	L-lactate permease	522
644107964	457	34.07	4	455	12	455	3.0e-72	266	COG0534	Na+-driven multidrug efflux pump	455
644107965	211	48.34	1	211	1	204	7.0e-70	257	COG0307	Riboflavin synthase alpha chain	204
644107966	383	48.23	97	371	1	282	4.0e-93	335	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
644107967	341	46.27	2	335	1	333	1.0e-95	343	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644107968	283	35.29	110	274	29	197	2.0e-32	133	COG0791	Cell wall-associated hydrolase, NlpC family	197
644107969	116	61.9	2	105	1	105	3.0e-44	170	COG0278	Glutaredoxin-related protein	105
644107970	223	34.6	8	217	1	236	7.0e-28	117	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
644107971	135	25.36	1	125	1	138	4.0e-13	67.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644107972	79	48.65	5	78	1	74	8.0e-15	72	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
644107973	145	29.27	14	135	5	126	2.0e-10	58.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
644107974	155	72.67	5	154	6	154	9.0e-38	149	COG3133	Outer membrane lipoprotein SlyB	154
644107975	370	61.89	1	368	2	371	1.0e-130	460	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
644107976	105	46.91	26	103	33	111	5.0e-19	85.9	COG3895	Membrane-bound inhibitor of C-type lysozyme	112
644107977	243	59.43	33	243	3	214	6.0e-88	317	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
644107978	425	51.42	3	424	2	401	0.0e+00	484	COG0162	Tyrosyl-tRNA synthetase	401
644107979	286	55.99	2	285	1	280	7.0e-97	347	COG2240	Pyridoxal/pyridoxine/pyridoxamine kinase	281
644107980	202	30.65	1	190	1	197	2.0e-28	118	COG0625	Glutathione S-transferase	211
644107981	434	42.41	3	416	1	405	5.0e-86	311	COG1301	Na+/H+-dicarboxylate symporter	415
644107982	890	65.77	5	890	1	860	0.0e+00	1250	COG1048	Aconitase A	861
644107985	544	36.83	7	543	2	562	2.0e-114	406	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
644107986	197	67.53	1	194	1	193	2.0e-74	271	COG0807	GTP cyclohydrolase II	193
644107987	258	20.09	36	233	1	214	7.0e-09	54.8	COG0671	Membrane-associated phospholipid phosphatase	232
644107988	313	39.34	5	305	12	314	2.0e-48	186	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
644107989	210	36.32	16	200	13	202	4.0e-36	144	COG5618	Predicted periplasmic lipoprotein	206
644107990	517	48.13	12	516	1	500	0.0e+00	554	COG1129	ABC-type sugar transport system, ATPase component	500
644107991	365	41.39	24	353	3	316	6.0e-57	215	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
644107992	276	55.83	6	244	5	243	5.0e-92	330	COG3959	Transketolase, N-terminal subunit	243
644107993	314	40.06	1	311	3	312	6.0e-94	337	COG3958	Transketolase, C-terminal subunit	312
644107994	496	45.49	3	496	4	499	0.0e+00	543	COG0554	Glycerol kinase	499
644107995	332	23.6	14	328	56	385	1.0e-15	77.4	COG4952	L-rhamnose isomerase	430
644107996	314	41.27	1	314	6	317	7.0e-74	270	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
644107997	101	76.4	1	89	1	89	2.0e-29	120	COG3771	Uncharacterized membrane protein YciS, DUF1049 family	97
644107998	389	69.15	1	389	1	389	0.0e+00	561	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
644107999	247	49.35	11	241	8	234	4.0e-70	257	COG0284	Orotidine-5'-phosphate decarboxylase	240
644108000	111	59.62	11	111	1	103	3.0e-25	106	COG0023	Translation initiation factor 1 (eIF-1/SUI1)	104
644108002	231	37.66	1	231	4	218	1.0e-59	223	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
644108003	687	43.47	32	685	1	575	0.0e+00	585	COG1966	Carbon starvation protein CstA	575
644108004	393	38.92	1	385	11	394	2.0e-63	237	COG2814	Predicted arabinose efflux permease, MFS family	394
644108005	167	40.52	16	165	1	153	8.0e-26	110	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644108006	305	44.79	1	305	1	298	4.0e-103	368	COG4989	Predicted oxidoreductase	298
644108007	644	75.5	1	644	1	645	0.0e+00	1106	COG4776	Exoribonuclease II	645
644108008	770	23.33	45	761	39	765	8.0e-103	368	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
644108009	300	29.37	1	300	1	295	4.0e-26	112	COG0583	DNA-binding transcriptional regulator, LysR family	297
644108010	356	24.85	6	341	2	333	6.0e-45	175	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644108011	436	22.45	15	436	20	445	8.0e-28	118	COG2271	Sugar phosphate permease	448
644108012	788	33.64	25	785	28	770	0.0e+00	621	COG1501	Alpha-glucosidase, glycosyl hydrolase family GH31	772
644108013	958	37.72	7	344	5	339	3.0e-81	297	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
644108014	327	36.84	14	315	37	337	3.0e-74	272	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
644108015	262	61.15	1	260	1	259	6.0e-110	390	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
644108016	271	79.7	2	267	1	266	3.0e-121	427	COG4167	ABC-type antimicrobial peptide transport system, ATPase component	267
644108017	330	85.15	1	330	1	330	0.0e+00	621	COG4170	ABC-type antimicrobial peptide transport system, ATPase component	330
644108018	296	74.66	1	296	1	296	3.0e-117	414	COG4171	ABC-type antimicrobial peptide transport system, permease component	296
644108019	321	74.14	1	321	1	321	1.0e-126	446	COG4168	ABC-type antimicrobial peptide transport system, permease component	321
644108020	562	27.74	8	537	5	555	5.0e-80	292	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
644108024	329	47.58	5	329	77	402	3.0e-89	321	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain	403
644108025	221	42.86	1	221	1	224	8.0e-29	120	COG1842	Phage shock protein A	225
644108027	121	41.27	8	69	3	65	4.0e-15	73.7	COG1983	Phage shock protein PspC (stress-responsive transcriptional regulator)	70
644108030	2599	16.08	622	1570	71	1013	3.0e-13	72.8	COG3210	Large exoprotein involved in heme utilization or adhesion	1013
644108031	171	44.44	19	152	14	147	1.0e-32	132	COG2994	ACP:hemolysin acyltransferase (hemolysin-activating protein)	148
644108032	580	40.59	38	580	18	554	0.0e+00	478	COG2831	Hemolysin activation/secretion protein	554
644108033	465	69.53	1	465	2	467	0.0e+00	729	COG3106	Predicted ATPase, YcjX-like family	467
644108034	347	58.84	4	346	1	345	4.0e-114	404	COG3768	Uncharacterized membrane protein YcjF, UPF0283 family	350
644108035	514	19.87	58	508	30	402	2.0e-34	140	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644108036	522	68.22	1	515	1	511	0.0e+00	731	COG3283	Transcriptional regulator of aromatic amino acids metabolism	511
644108037	167	61.15	3	159	2	158	2.0e-63	235	COG2077	Peroxiredoxin	158
644108039	538	40.04	10	537	12	562	1.0e-121	430	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
644108040	327	24.22	12	327	2	322	1.0e-57	217	COG0598	Mg2+ and Co2+ transporter CorA	322
644108042	311	35.02	17	287	1	270	1.0e-54	207	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
644108045	271	26.26	1	92	2	100	2.0e-12	66.6	COG0633	Ferredoxin	102
644108046	113	34.07	23	113	5	85	1.0e-09	55	COG3042	Putative hemolysin	85
644108047	330	47.76	1	328	1	321	4.0e-96	344	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
644108048	517	32.17	194	513	62	406	2.0e-42	167	COG0840	Methyl-accepting chemotaxis protein	408
644108049	517	29.13	160	515	30	408	4.0e-45	176	COG0840	Methyl-accepting chemotaxis protein	408
644108052	201	53.96	1	199	1	202	7.0e-71	260	COG1182	FMN-dependent NADH-azoreductase	202
644108053	1295	39.85	18	956	1	845	0.0e+00	843	COG1643	HrpA-like RNA helicase	845
644108055	592	40.47	333	589	2	255	1.0e-69	258	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644108056	288	27.57	1	271	1	251	6.0e-50	191	COG3591	V8-like Glu-specific endopeptidase	251
644108058	437	28.02	100	430	3	335	4.0e-36	146	COG0642	Signal transduction histidine kinase	336
644108059	245	40.59	2	238	1	228	4.0e-52	198	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644108060	191	27.72	1	181	1	184	2.0e-21	95.8	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
644108061	267	17.37	8	263	4	253	1.0e-05	43.9	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
644108062	158	31.97	3	145	27	173	1.0e-19	89.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644108063	240	24.8	4	238	3	251	3.0e-27	115	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644108065	572	40.29	20	561	12	546	2.0e-108	386	COG0659	Sulfate permease or related transporter, MFS superfamily	554
644108066	366	42.01	5	366	2	366	9.0e-71	260	COG0387	Ca2+/H+ antiporter	368
644108067	267	35.6	7	253	17	265	2.0e-45	176	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
644108068	227	44.2	34	213	1	179	6.0e-48	183	COG3703	Cation transport regulator ChaC	190
644108070	425	21.16	5	348	11	319	2.0e-19	90.6	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
644108071	216	44.71	9	216	3	209	1.0e-51	196	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644108072	623	42.35	28	610	1	569	0.0e+00	537	COG3850	Signal transduction histidine kinase, nitrate/nitrite-specific	574
644108073	477	43.37	39	476	1	405	2.0e-96	346	COG2223	Nitrate/nitrite transporter NarK	417
644108075	1253	77.67	1	1235	1	1227	0.0e+00	2178	COG5013	Nitrate reductase alpha subunit	1227
644108076	521	84.09	1	507	1	509	0.0e+00	963	COG1140	Nitrate reductase beta subunit	513
644108077	239	50.56	1	180	4	179	2.0e-44	172	COG2180	Nitrate reductase assembly protein NarJ, required for insertion of molybdenum cofactor	179
644108078	229	59.11	7	229	1	225	3.0e-67	248	COG2181	Nitrate reductase gamma subunit	228
644108079	290	22.98	45	288	46	286	3.0e-08	53	COG5006	Threonine/homoserine efflux transporter RhtA	292
644108080	187	29.84	43	166	5	125	3.0e-09	55.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
644108081	380	34.63	7	366	13	357	2.0e-63	236	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
644108082	312	37.06	1	301	4	316	3.0e-65	242	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
644108083	324	46.25	1	316	1	320	1.0e-107	383	COG1171	Threonine dehydratase	347
644108084	207	26.79	5	207	6	214	7.0e-37	146	COG2964	Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains	220
644108086	421	31.59	3	359	4	354	2.0e-65	243	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
644108088	82	53.09	1	81	1	80	3.0e-08	50.4	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
644108089	364	46.8	1	358	2	350	2.0e-113	402	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644108090	497	37.24	17	490	1	456	1.0e-108	387	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644108091	421	50.58	1	421	16	445	0.0e+00	490	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
644108092	488	50	17	488	3	471	0.0e+00	536	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644108093	359	26.27	11	357	3	363	3.0e-51	196	COG0687	Spermidine/putrescine-binding periplasmic protein	363
644108094	422	44.49	143	414	9	279	6.0e-64	238	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
644108095	272	44.66	15	267	12	264	9.0e-57	213	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
644108096	244	32.68	5	242	6	250	3.0e-38	151	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644108099	519	34.95	141	506	17	408	2.0e-50	193	COG0840	Methyl-accepting chemotaxis protein	408
644108100	55	78.18	1	55	1	55	6.0e-17	78.9	COG3130	Ribosome modulation factor	55
644108101	188	45.83	1	188	1	190	8.0e-43	166	COG3009	Uncharacterized lipoprotein YmbA	190
644108102	546	45.39	9	546	12	552	0.0e+00	616	COG3008	Paraquat-inducible protein B	553
644108103	414	47.56	2	410	20	418	2.0e-125	442	COG2995	Uncharacterized paraquat-inducible protein A	418
644108105	642	44.57	1	537	1	528	0.0e+00	545	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644108106	705	53.28	1	380	2	377	0.0e+00	477	COG0116	23S rRNA G2445 N2-methylase RlmL	381
644108107	367	60.07	1	267	1	266	8.0e-92	330	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
644108109	336	44.3	46	336	3	288	5.0e-90	324	COG0167	Dihydroorotate dehydrogenase	310
644108110	871	43.12	1	864	5	859	0.0e+00	732	COG0308	Aminopeptidase N	859
644108111	401	37.25	1	399	3	381	2.0e-98	352	COG1488	Nicotinic acid phosphoribosyltransferase	405
644108112	466	47.33	1	466	2	435	0.0e+00	546	COG0017	Aspartyl/asparaginyl-tRNA synthetase	435
644108113	370	52.8	2	370	1	354	2.0e-65	243	COG3203	Outer membrane protein (porin)	354
644108114	396	62.88	1	396	1	396	0.0e+00	626	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
644108115	215	35.68	1	213	12	252	7.0e-34	137	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644108116	182	54.95	1	182	1	182	7.0e-67	246	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
644108117	578	44.96	25	578	34	561	0.0e+00	539	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
644108118	1479	82.76	1	1479	1	1479	0.0e+00	2136	COG3096	Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Escherichia coli str. K-12 substr. MG1655	1480
644108119	240	80.25	3	240	1	237	4.0e-107	380	COG3095	Chromosome condensin MukBEF, MukE localization factor	238
644108120	441	85.03	1	441	1	440	0.0e+00	721	COG3006	Chromosome condensin MukBEF complex, kleisin-like MukF subunit	440
644108122	282	31.82	16	254	1	222	6.0e-26	111	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
644108125	250	64.8	1	250	2	245	3.0e-104	371	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
644108126	60	66.67	1	57	1	57	3.0e-18	83.3	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
644108127	333	55.41	1	308	4	314	4.0e-105	374	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
644108128	582	39.27	10	582	1	567	0.0e+00	473	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
644108129	757	36.79	458	743	2	292	2.0e-64	241	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
644108130	105	82.52	3	105	2	104	3.0e-31	126	COG2926	Uncharacterized conserved protein YeeX, DUF496 family	109
644108131	252	57.94	1	252	1	252	2.0e-107	382	COG4604	ABC-type enterochelin transport system, ATPase component	252
644108132	335	55.37	26	332	7	313	4.0e-82	298	COG4605	ABC-type enterochelin transport system, permease component	316
644108133	320	61.29	9	317	10	319	2.0e-99	355	COG4606	ABC-type enterochelin transport system, permease component	321
644108134	321	47.5	2	319	4	320	3.0e-100	358	COG4607	ABC-type enterochelin transport system, periplasmic component	320
644108135	475	73.84	1	474	3	475	0.0e+00	765	COG2925	Exonuclease I	475
644108136	456	26.52	16	445	9	447	2.0e-31	130	COG0531	Amino acid transporter	466
644108138	251	32.05	16	248	6	233	4.0e-39	155	COG5581	c-di-GMP-binding flagellar brake protein YcgR, contains PilZNR and PilZ domains	233
644108140	301	44.8	31	300	7	285	2.0e-60	225	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
644108141	175	40.96	6	171	11	176	2.0e-41	162	COG3697	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase)	182
644108142	509	70	18	506	24	513	0.0e+00	778	COG3051	Citrate lyase, alpha subunit	513
644108143	291	44.6	7	291	1	282	9.0e-76	277	COG2301	Citrate lyase beta subunit	283
644108144	96	50.52	1	96	1	97	9.0e-25	105	COG3052	Citrate lyase, gamma subunit	98
644108145	354	49.09	24	350	20	338	3.0e-107	382	COG3053	Citrate lyase synthetase	352
644108146	294	37.32	10	278	1	265	1.0e-62	233	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
644108147	456	39.67	33	455	18	438	2.0e-98	353	COG3493	Na+/citrate or Na+/malate symporter	438
644108148	531	36.59	1	531	4	534	8.0e-121	427	COG3290	Sensor histidine kinase regulating citrate/malate metabolism	537
644108149	233	37.67	8	230	2	222	4.0e-55	208	COG4565	Response regulator of citrate/malate metabolism	224
644108150	644	39.62	262	607	38	408	5.0e-51	196	COG0840	Methyl-accepting chemotaxis protein	408
644108151	650	38.01	264	609	38	408	4.0e-48	186	COG0840	Methyl-accepting chemotaxis protein	408
644108152	278	23.49	2	267	1	296	7.0e-24	104	COG0451	Nucleoside-diphosphate-sugar epimerase	314
644108153	299	57.24	5	299	1	290	3.0e-102	364	COG0040	ATP phosphoribosyltransferase	290
644108154	444	52.8	19	441	1	425	0.0e+00	560	COG0141	Histidinol dehydrogenase	425
644108155	357	43.14	7	352	1	351	1.0e-91	330	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
644108156	355	61.03	164	355	1	195	5.0e-85	308	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
644108157	196	55.22	1	196	2	202	1.0e-77	282	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
644108158	245	51.22	1	245	3	241	6.0e-80	290	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
644108159	258	54.62	1	258	1	256	2.0e-110	392	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
644108160	210	53.33	8	111	3	106	3.0e-39	155	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
644108161	94	48.39	1	93	2	93	3.0e-28	116	COG0776	Bacterial nucleoid DNA-binding protein	94
644108162	557	59.35	1	550	1	541	0.0e+00	612	COG0539	Ribosomal protein S1	541
644108163	225	60.09	4	225	3	222	4.0e-78	284	COG0283	Cytidylate kinase	222
644108164	429	50.58	3	426	2	425	0.0e+00	494	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
644108165	361	60.99	1	361	3	365	0.0e+00	520	COG1932	Phosphoserine aminotransferase	365
644108166	587	45.84	1	418	4	396	1.0e-116	413	COG1944	Ribosomal protein S12 methylthiotransferase accessory factor YcaO	398
644108167	286	52.13	5	285	1	264	5.0e-69	254	COG2116	Formate/nitrite transporter FocA, FNT family	265
644108168	760	67.24	2	759	1	755	0.0e+00	1118	COG1882	Pyruvate-formate lyase	755
644108169	246	37.65	1	246	15	257	9.0e-74	269	COG1180	Pyruvate-formate lyase-activating enzyme	260
644108171	369	46.85	1	365	1	357	1.0e-113	403	COG3535	Uncharacterized conserved protein, DUF917 family	357
644108172	434	30.58	18	418	7	413	1.0e-38	154	COG1457	Purine-cytosine permease or related protein	442
644108173	313	24	6	303	1	296	2.0e-27	116	COG0583	DNA-binding transcriptional regulator, LysR family	297
644108174	384	18.97	9	383	15	418	3.0e-09	56.4	COG0738	Fucose permease	422
644108175	431	61.75	1	431	1	426	0.0e+00	595	COG0172	Seryl-tRNA synthetase	429
644108176	447	62.5	4	442	1	435	0.0e+00	635	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
644108177	203	45.45	1	202	5	211	5.0e-44	170	COG2834	Outer membrane lipoprotein-sorting protein	211
644108178	1162	35.92	440	1160	157	856	0.0e+00	520	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
644108179	164	49.35	8	161	2	154	7.0e-38	150	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644108180	320	51.6	5	314	2	301	9.0e-94	337	COG0492	Thioredoxin reductase	305
644108181	588	54.77	23	586	1	557	0.0e+00	626	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
644108182	573	57.99	1	571	1	571	0.0e+00	629	COG4987	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components	573
644108183	234	57.08	13	229	3	220	2.0e-79	288	COG2360	Leu/Phe-tRNA-protein transferase	221
644108184	72	72.22	1	72	1	72	1.0e-25	107	COG0361	Translation initiation factor IF-1	75
644108185	481	36.54	17	477	3	458	1.0e-98	353	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644108187	757	48.63	1	746	1	786	0.0e+00	872	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
644108188	106	56.6	1	106	2	107	6.0e-33	132	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
644108190	73	59.09	1	66	1	66	2.0e-23	100	COG1278	Cold shock protein, CspA family	67
644108191	554	45.53	1	554	1	580	0.0e+00	489	COG3593	Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains	581
644108192	299	58.86	1	299	1	297	1.0e-73	270	COG2431	Uncharacterized membrane protein YbjE, DUF340 family	297
644108193	550	45	1	548	4	560	0.0e+00	650	COG1151	Hydroxylamine reductase (hybrid-cluster protein)	576
644108194	341	35.64	11	282	1	266	2.0e-56	213	COG1018	Ferredoxin-NADP reductase	266
644108196	478	28.37	6	284	1	275	4.0e-34	139	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
644108197	275	42.8	13	271	9	257	6.0e-66	244	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
644108198	107	54.21	1	107	1	107	1.0e-33	134	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
644108199	242	85.54	1	242	1	242	3.0e-123	434	COG4161	ABC-type arginine transport system, ATPase component	242
644108200	243	36.9	4	243	17	265	3.0e-43	168	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644108201	238	51.71	4	237	7	230	3.0e-69	255	COG4215	ABC-type arginine transport system, permease component	230
644108202	222	53.36	1	221	6	228	1.0e-69	255	COG4160	ABC-type arginine/histidine transport system, permease component	228
644108203	243	40	1	243	4	265	5.0e-43	167	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644108204	377	35.77	9	368	73	432	1.0e-89	323	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
644108206	281	45.96	1	271	2	266	1.0e-57	216	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
644108207	321	50.34	32	321	8	286	4.0e-76	278	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
644108208	377	52.75	15	377	1	352	2.0e-125	442	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644108209	369	47.18	1	369	1	363	2.0e-95	342	COG0687	Spermidine/putrescine-binding periplasmic protein	363
644108211	303	34.28	1	292	1	317	5.0e-64	237	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
644108212	239	27.27	1	181	2	207	4.0e-19	88.5	COG0778	Nitroreductase	207
644108213	88	31.76	1	85	1	80	6.0e-17	78.9	COG0695	Glutaredoxin	80
644108215	562	50.72	5	558	1	543	0.0e+00	584	COG2985	Uncharacterized membrane protein YbjL, putative transporter	544
644108216	222	58.04	1	222	5	228	3.0e-73	268	COG0274	Deoxyribose-phosphate aldolase	228
644108217	257	35.97	3	253	1	250	3.0e-59	222	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
644108218	401	51.09	33	396	31	389	1.0e-116	413	COG1686	D-alanyl-D-alanine carboxypeptidase	389
644108220	219	57.48	3	216	9	222	9.0e-68	250	COG2011	ABC-type methionine transport system, permease component	222
644108221	338	56.34	1	336	1	337	8.0e-119	420	COG1135	ABC-type methionine transport system, ATPase component	339
644108222	281	40.66	1	271	1	268	1.0e-67	250	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
644108223	205	30.35	2	198	1	200	4.0e-35	141	COG0625	Glutathione S-transferase	211
644108224	388	44.29	44	388	58	397	5.0e-93	334	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
644108225	437	38.84	4	437	3	436	0.0e+00	481	COG0621	tRNA A37 methylthiotransferase MiaB	437
644108226	259	64.32	1	225	13	234	8.0e-89	319	COG2949	Uncharacterized periplasmic protein SanA, affects membrane permeability for vancomycin	235
644108227	391	42.49	8	384	5	381	3.0e-70	259	COG2311	Uncharacterized membrane protein YeiB	394
644108228	220	47.67	29	219	6	195	9.0e-67	246	COG0302	GTP cyclohydrolase I	195
644108229	522	36.17	130	480	33	408	2.0e-47	184	COG0840	Methyl-accepting chemotaxis protein	408
644108230	296	35.62	1	285	1	290	2.0e-37	149	COG0583	DNA-binding transcriptional regulator, LysR family	297
644108231	373	69.65	4	372	1	366	0.0e+00	574	COG1062	Zn-dependent alcohol dehydrogenase	366
644108232	281	37.42	1	278	3	312	7.0e-76	277	COG0627	S-formylglutathione hydrolase FrmB	316
644108234	214	27.44	1	210	1	201	2.0e-26	112	COG0625	Glutathione S-transferase	211
644108236	362	36.09	6	361	2	358	3.0e-80	292	COG0371	Glycerol dehydrogenase or related enzyme, iron-containing ADH family	360
644108237	503	45.02	1	500	1	500	0.0e+00	528	COG1129	ABC-type sugar transport system, ATPase component	500
644108238	331	41.72	20	331	7	311	6.0e-49	188	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
644108239	329	38.2	10	324	1	313	4.0e-79	288	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
644108240	697	39.81	2	697	11	699	0.0e+00	619	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
644108241	491	53.78	5	491	31	518	0.0e+00	618	COG0833	Amino acid permease	541
644108242	290	33.9	3	288	1	289	3.0e-37	149	COG0583	DNA-binding transcriptional regulator, LysR family	297
644108243	329	45.68	1	324	19	333	4.0e-77	282	COG2855	Uncharacterized membrane protein YadS	334
644108244	281	49.64	1	278	1	274	2.0e-94	338	COG0648	Endonuclease IV	280
644108245	563	63.64	226	560	1	339	7.0e-99	354	COG1299	Phosphotransferase system, fructose-specific IIC component	343
644108246	312	48.39	4	312	1	310	1.0e-107	383	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
644108247	377	60.56	2	143	1	142	3.0e-52	199	COG4668	Mannitol/fructose-specific phosphotransferase system, IIA domain	142
644108248	430	19.37	45	425	6	383	2.0e-08	54.1	COG2814	Predicted arabinose efflux permease, MFS family	394
644108250	190	36.84	1	133	3	131	2.0e-30	125	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
644108251	333	30.56	3	330	1	316	3.0e-62	232	COG0523	GTPase, G3E family	323
644108253	193	30.96	2	184	1	197	7.0e-26	110	COG0791	Cell wall-associated hydrolase, NlpC family	197
644108254	602	29.04	1	595	5	562	9.0e-89	321	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
644108255	365	73.97	1	365	1	364	0.0e+00	586	COG4174	ABC-type microcin C transport system, permease component YejB	364
644108256	341	71.76	1	340	1	340	0.0e+00	518	COG4239	ABC-type microcin C transport system, permease component YejE	341
644108257	538	64.52	1	526	1	527	0.0e+00	785	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
644108259	396	20.45	1	396	4	392	3.0e-19	89.9	COG2814	Predicted arabinose efflux permease, MFS family	394
644108260	231	41.67	1	231	3	242	2.0e-66	245	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
644108262	586	32.63	1	368	33	400	1.0e-72	268	COG1061	Superfamily II DNA or RNA helicase	442
644108263	94	53.19	1	94	1	93	2.0e-22	97.3	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
644108264	382	33.92	8	345	15	323	8.0e-54	204	COG3503	Uncharacterized membrane protein	323
644108265	336	77.84	1	334	1	334	0.0e+00	527	COG3081	Nucleoid-associated protein YejK (function unknown)	335
644108266	76	73.24	1	71	1	71	2.0e-23	100	COG3082	Uncharacterized conserved protein YejL, UPF0352 family	74
644108267	582	57.33	1	582	1	600	0.0e+00	707	COG3083	Membrane-anchored periplasmic protein YejM, alkaline phosphatase superfamily	600
644108269	394	86.29	1	394	1	394	0.0e+00	727	COG0050	Translation elongation factor EF-Tu, a GTPase	394
644108270	704	67.71	1	704	1	693	0.0e+00	1015	COG0480	Translation elongation factor EF-G, a GTPase	697
644108271	156	61.49	2	149	1	148	4.0e-54	203	COG0049	Ribosomal protein S7	148
644108272	124	76.42	1	123	7	129	6.0e-50	189	COG0048	Ribosomal protein S12	129
644108273	95	57.29	1	95	1	96	3.0e-22	96.9	COG2168	Sulfur transfer complex TusBCD TusB component, DsrH family	96
644108274	119	57.14	1	119	1	118	2.0e-38	151	COG2923	Sulfur relay (sulfurtransferase) complex TusC component, DsrF/TusC family	118
644108275	129	53.12	2	129	1	126	2.0e-39	154	COG1553	Sulfur relay (sulfurtransferase) complex TusBCD TusD component, DsrE family	126
644108276	240	62.73	19	235	1	220	8.0e-78	283	COG2964	Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains	220
644108277	542	41.38	3	542	7	549	0.0e+00	501	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
644108278	222	42.48	1	216	1	225	2.0e-54	205	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644108279	364	27.27	31	354	2	327	1.0e-29	124	COG0642	Signal transduction histidine kinase	336
644108280	422	65.38	7	422	6	412	0.0e+00	662	COG0112	Glycine/serine hydroxymethyltransferase	413
644108281	270	48.7	25	254	2	228	2.0e-79	289	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
644108282	497	33.82	20	496	1	456	3.0e-103	369	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644108284	277	55.24	45	253	2	205	1.0e-54	206	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
644108285	72	48.61	1	72	1	72	3.0e-11	59.9	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
644108286	194	52.17	1	183	1	174	3.0e-48	184	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
644108287	64	55.56	2	64	4	66	7.0e-15	72.4	COG3529	Predicted nucleic-acid-binding protein, contains Zn-ribbon domain	66
644108288	183	34.92	6	179	2	189	1.0e-40	158	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
644108289	635	46.31	1	519	3	527	0.0e+00	545	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644108290	200	31.03	1	198	1	203	6.0e-20	90.7	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644108291	346	57.32	5	326	19	345	2.0e-112	398	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
644108292	78	80	1	70	1	70	3.0e-26	110	COG3089	Uncharacterized conserved protein YheU, UPF0270 family	72
644108293	289	86.51	1	289	1	289	0.0e+00	524	COG3954	Phosphoribulokinase	289
644108294	135	52.21	1	132	2	136	7.0e-34	136	COG1765	Uncharacterized OsmC-related protein	137
644108295	210	36.95	9	210	13	214	9.0e-40	156	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
644108296	408	54.93	1	405	1	401	0.0e+00	567	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
644108297	191	60.73	1	191	3	190	2.0e-82	297	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
644108303	425	24.8	1	363	1	341	2.0e-06	47.3	COG3866	Pectate lyase	345
644108304	190	49.69	30	190	1	158	4.0e-51	194	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
644108305	269	50.2	10	261	1	252	2.0e-83	302	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
644108306	274	51.31	1	263	2	268	3.0e-93	334	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
644108307	307	51.61	31	307	9	287	1.0e-73	270	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644108308	346	45.32	13	343	2	312	2.0e-82	299	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644108309	520	26.19	2	518	27	552	5.0e-64	239	COG0747	ABC-type transport system, periplasmic component	556
644108310	384	30.1	1	384	1	371	2.0e-54	206	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644108312	850	50.43	1	810	1	793	0.0e+00	1058	COG1251	NAD(P)H-nitrite reductase, large subunit	793
644108313	122	37.61	1	108	2	105	2.0e-19	88.1	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
644108314	459	57.44	215	454	3	243	3.0e-89	322	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
644108315	238	47.16	12	238	1	229	4.0e-60	224	COG4215	ABC-type arginine transport system, permease component	230
644108316	244	51.75	1	227	1	228	3.0e-65	241	COG4160	ABC-type arginine/histidine transport system, permease component	228
644108317	254	64.03	1	253	2	254	6.0e-111	393	COG4598	ABC-type histidine transport system, ATPase component	256
644108318	289	29.59	3	288	2	269	5.0e-33	134	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644108319	485	23.6	26	459	8	392	1.0e-52	201	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
644108320	334	52.83	1	312	3	314	1.0e-115	409	COG0180	Tryptophanyl-tRNA synthetase	314
644108321	234	44.14	4	225	1	220	1.0e-50	193	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
644108322	225	58.56	1	222	1	220	5.0e-87	314	COG0036	Pentose-5-phosphate-3-epimerase	220
644108323	270	50	3	269	1	271	1.0e-75	276	COG0338	Site-specific DNA-adenine methylase	274
644108324	338	36.89	38	336	9	291	8.0e-36	144	COG3266	Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain	292
644108325	361	59	1	361	1	359	0.0e+00	500	COG0337	3-dehydroquinate synthetase	360
644108326	173	54.71	4	173	2	169	3.0e-55	207	COG0703	Shikimate kinase	172
644108330	189	27.12	4	179	7	182	4.0e-12	64.6	COG3166	Tfp pilus assembly protein PilN	206
644108332	851	53.04	1	849	2	786	0.0e+00	1056	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
644108336	228	22.37	7	222	1	227	3.0e-23	101	COG1011	FMN phosphatase YigB, HAD superfamily	229
644108337	136	57.14	5	102	2	99	5.0e-26	110	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
644108338	289	49.12	1	279	2	286	2.0e-95	342	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
644108339	539	65.19	4	539	3	529	0.0e+00	836	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
644108340	453	29.87	142	445	22	336	8.0e-36	145	COG0642	Signal transduction histidine kinase	336
644108341	239	42.92	5	236	1	229	4.0e-63	234	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644108343	386	22.73	13	357	8	319	3.0e-38	153	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
644108344	416	20.81	58	402	59	394	2.0e-13	70.2	COG2814	Predicted arabinose efflux permease, MFS family	394
644108346	338	41.37	2	303	1	300	4.0e-73	268	COG0031	Cysteine synthase	300
644108347	467	23.46	46	449	21	390	8.0e-40	158	COG0019	Diaminopimelate decarboxylase	394
644108348	688	23.71	9	688	43	768	2.0e-38	154	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644108350	633	22.08	26	573	19	544	6.0e-53	202	COG4264	Siderophore synthetase component	602
644108351	293	33.67	8	289	3	275	4.0e-48	185	COG2301	Citrate lyase beta subunit	283
644108352	159	42.11	6	156	1	150	7.0e-37	146	COG0782	Transcription elongation factor, GreA/GreB family	151
644108353	555	36.04	153	520	19	408	8.0e-44	172	COG0840	Methyl-accepting chemotaxis protein	408
644108354	428	45.73	28	424	2	386	2.0e-118	419	COG0372	Citrate synthase	390
644108355	777	61.1	1	777	6	780	0.0e+00	1051	COG2183	Transcriptional accessory protein Tex/SPT6	780
644108356	262	35.54	13	252	1	242	2.0e-49	189	COG1414	DNA-binding transcriptional regulator, IclR family	246
644108358	278	64.03	1	278	1	278	7.0e-122	430	COG3717	5-keto 4-deoxyuronate isomerase	278
644108359	349	41.59	27	344	18	342	9.0e-81	294	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
644108362	267	23.92	5	264	51	313	2.0e-14	72.9	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
644108363	92	23.96	1	89	1	96	3.0e-10	57	COG0633	Ferredoxin	102
644108365	273	20.8	15	272	14	277	3.0e-11	62.7	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
644108366	250	31.54	1	239	6	244	5.0e-33	134	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
644108367	503	24.21	57	452	75	455	9.0e-26	112	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
644108370	230	37.67	6	224	4	225	7.0e-56	210	COG1136	ABC-type lipoprotein export system, ATPase component	226
644108372	581	31.91	116	578	52	482	1.0e-78	288	COG1785	Alkaline phosphatase	482
644108373	327	30.15	6	324	11	323	4.0e-55	208	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
644108374	204	32.85	1	204	1	207	1.0e-21	96.9	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644108375	1038	54.46	1	1029	2	1009	0.0e+00	1047	COG0841	Multidrug efflux pump subunit AcrB	1009
644108376	255	28.21	1	255	9	281	4.0e-22	98.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644108377	233	41.03	1	233	7	224	1.0e-47	183	COG1040	Predicted amidophosphoribosyltransferases	225
644108378	191	50.54	98	189	1	93	2.0e-27	115	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
644108379	694	40.21	127	685	1	516	0.0e+00	504	COG1640	4-alpha-glucanotransferase	520
644108380	840	45.76	45	840	7	750	0.0e+00	811	COG0058	Glucan phosphorylase	750
644108381	252	42.06	1	252	1	252	7.0e-76	277	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
644108382	276	30.15	93	272	15	213	1.0e-23	103	COG0705	Membrane associated serine protease, rhomboid family	228
644108383	107	33.33	1	95	1	99	7.0e-16	75.7	COG0607	Rhodanese-related sulfurtransferase	110
644108384	499	50.4	1	489	10	506	0.0e+00	581	COG0578	Glycerol-3-phosphate dehydrogenase	532
644108385	815	50.43	9	812	1	750	0.0e+00	928	COG0058	Glucan phosphorylase	750
644108386	479	51.65	1	476	1	478	0.0e+00	523	COG0297	Glycogen synthase	487
644108387	425	53.28	15	425	1	389	0.0e+00	541	COG0448	ADP-glucose pyrophosphorylase	393
644108388	658	50	1	656	9	692	0.0e+00	773	COG1523	Pullulanase/glycogen debranching enzyme	697
644108389	725	60.38	98	721	1	626	0.0e+00	806	COG0296	1,4-alpha-glucan branching enzyme	628
644108390	572	62.66	4	558	1	551	0.0e+00	740	COG3275	Sensor histidine kinase, LytS/YehU family	557
644108392	367	34.15	1	367	1	334	6.0e-100	358	COG0136	Aspartate-semialdehyde dehydrogenase	334
644108393	197	42.42	1	196	4	201	1.0e-35	143	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
644108394	458	42.63	13	458	3	442	4.0e-83	302	COG2610	H+/gluconate symporter or related permease	442
644108395	170	62.5	9	168	1	159	7.0e-64	236	COG3265	Gluconate kinase	161
644108396	331	34.35	6	331	1	329	5.0e-75	274	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644108397	231	37.8	1	231	1	245	3.0e-57	214	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
644108400	786	21.55	504	781	60	328	3.0e-18	87.9	COG0642	Signal transduction histidine kinase	336
644108405	342	21.43	11	233	12	208	8.0e-10	58.1	COG0412	Dienelactone hydrolase	236
644108406	399	21.82	8	391	6	382	1.0e-15	77.9	COG2814	Predicted arabinose efflux permease, MFS family	394
644108407	1029	28.46	7	1015	1	1009	0.0e+00	810	COG0841	Multidrug efflux pump subunit AcrB	1009
644108408	369	27.76	1	361	4	372	4.0e-20	92.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644108409	200	18.69	3	200	2	199	2.0e-08	52.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644108410	505	33.67	13	505	1	456	7.0e-49	188	COG1538	Outer membrane protein TolC	457
644108411	261	40.38	1	259	1	260	4.0e-61	228	COG0300	Short-chain dehydrogenase	265
644108413	599	51.84	1	598	4	601	0.0e+00	818	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
644108414	499	31.14	24	498	17	528	3.0e-82	299	COG0659	Sulfate permease or related transporter, MFS superfamily	554
644108416	330	55.14	6	324	1	316	5.0e-120	424	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
644108417	287	49.45	1	270	15	287	3.0e-61	228	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644108418	318	47	1	315	1	317	3.0e-82	298	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644108419	521	25.75	8	507	18	539	8.0e-61	228	COG0747	ABC-type transport system, periplasmic component	556
644108420	405	30.71	17	382	10	389	2.0e-54	207	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
644108421	268	38.82	5	259	2	256	4.0e-48	184	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
644108422	293	40.79	14	289	9	284	6.0e-46	178	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
644108423	365	47.65	1	360	3	352	4.0e-111	394	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644108424	361	29.97	1	318	1	318	1.0e-41	164	COG0687	Spermidine/putrescine-binding periplasmic protein	363
644108425	664	39.18	2	574	1	562	0.0e+00	470	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
644108426	693	36.8	10	684	4	671	0.0e+00	475	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
644108427	497	21.89	22	481	10	406	2.0e-25	110	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644108429	393	34.05	13	378	30	371	5.0e-69	254	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644108430	277	24.62	10	259	6	264	7.0e-23	101	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644108431	469	25.49	8	461	5	441	7.0e-47	182	COG2079	2-methylcitrate dehydratase PrpD	453
644108432	225	42.52	5	218	6	219	8.0e-52	196	COG0765	ABC-type amino acid transport system, permease component	222
644108433	221	47.2	5	218	6	219	1.0e-55	209	COG0765	ABC-type amino acid transport system, permease component	222
644108434	282	57.26	30	277	2	239	2.0e-96	345	COG1126	ABC-type polar amino acid transport system, ATPase component	240
644108435	305	31.94	21	303	1	281	8.0e-49	187	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
644108436	684	25.58	363	533	59	224	4.0e-11	63.9	COG2849	Antitoxin component YwqK of the YwqJK toxin-antitoxin module	230
644108437	305	27.48	5	304	1	297	1.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
644108438	402	22.73	10	307	8	311	3.0e-19	89.9	COG2814	Predicted arabinose efflux permease, MFS family	394
644108439	210	38.5	7	205	6	204	1.0e-31	129	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644108440	158	75.82	6	158	2	154	6.0e-67	246	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
644108441	189	21.62	1	183	6	190	3.0e-09	55.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644108442	350	32.23	52	349	38	331	2.0e-36	146	COG0642	Signal transduction histidine kinase	336
644108443	175	36.16	1	173	53	225	8.0e-37	146	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644108445	375	28.57	1	374	4	372	6.0e-29	122	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644108446	1032	49.17	1	1018	2	1003	0.0e+00	979	COG0841	Multidrug efflux pump subunit AcrB	1009
644108447	135	29	11	110	21	120	6.0e-19	86.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644108448	362	38.51	1	345	3	338	4.0e-93	335	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
644108449	101	31.07	1	101	2	104	1.0e-06	44.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
644108450	515	35.86	1	489	3	502	2.0e-100	359	COG1070	Sugar (pentulose or hexulose) kinase	502
644108451	342	37.46	1	338	2	312	6.0e-72	264	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
644108452	313	32.59	5	311	1	311	4.0e-42	165	COG0524	Sugar or nucleoside kinase, ribokinase family	311
644108453	332	40.07	27	332	14	316	1.0e-41	163	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
644108454	330	36.04	21	327	13	312	4.0e-36	145	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
644108455	515	47.07	15	509	9	500	0.0e+00	552	COG1129	ABC-type sugar transport system, ATPase component	500
644108456	309	27.52	14	301	32	317	5.0e-24	105	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
644108457	173	40.7	1	170	1	166	7.0e-42	163	COG1791	Acireductone dioxygenase (methionine salvage), cupin superfamily	181
644108458	154	65.13	1	152	1	152	8.0e-59	219	COG4807	Uncharacterized conserved protein YehS, DUF1456 family	155
644108460	277	53.31	20	261	4	243	1.0e-83	302	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
644108461	902	30.96	3	696	38	761	0.0e+00	462	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
644108462	1410	32.43	1283	1391	3	106	9.0e-11	63.8	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
644108462	1410	47.17	432	1240	1	793	0.0e+00	947	COG1251	NAD(P)H-nitrite reductase, large subunit	793
644108463	264	45	4	263	1	248	6.0e-86	310	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
644108464	305	36.14	56	300	11	250	3.0e-45	176	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
644108465	419	29.2	26	360	10	335	3.0e-49	189	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
644108469	379	46.3	1	374	1	346	2.0e-86	312	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
644108471	121	42.06	15	120	11	117	3.0e-18	83.8	COG2149	Uncharacterized membrane protein YidH, DUF202 family	120
644108473	309	64.4	1	304	1	305	2.0e-105	375	COG3058	Formate dehydrogenase maturation protein FdhE	308
644108475	483	37.5	1	476	3	459	2.0e-110	392	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644108476	240	32.04	23	201	11	188	8.0e-34	137	COG0518	GMP synthase - Glutamine amidotransferase domain	198
644108478	209	23	1	203	1	204	2.0e-06	45.7	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
644108479	166	62.03	5	162	18	175	6.0e-57	213	COG3721	Putative heme iron utilization protein	176
644108480	437	28.12	25	430	7	416	3.0e-82	299	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
644108481	722	24.3	1	603	1	563	1.0e-41	165	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
644108482	274	42.58	22	274	44	298	4.0e-61	228	COG4558	ABC-type hemin transport system, periplasmic component	300
644108483	522	43.45	1	522	11	530	0.0e+00	581	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644108484	298	37.04	5	297	4	290	3.0e-65	242	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
644108485	186	22.16	22	182	9	175	2.0e-13	69.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644108487	472	28.46	96	463	1	376	3.0e-68	252	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
644108488	565	42.7	13	529	1	505	3.0e-111	396	COG0366	Glycosidase	505
644108489	103	43.01	12	103	12	104	2.0e-20	91.1	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
644108490	485	45.51	4	481	1	470	1.0e-99	357	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
644108491	511	52.27	1	505	4	494	0.0e+00	531	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
644108492	615	43.48	4	611	1	606	3.0e-125	442	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
644108493	100	62	1	100	1	100	1.0e-25	107	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
644108494	186	37.2	1	163	4	166	9.0e-25	106	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
644108495	180	42.07	10	172	12	170	1.0e-41	162	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
644108496	324	53.8	1	322	1	329	8.0e-105	373	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
644108497	911	37.45	4	786	1	693	0.0e+00	704	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
644108498	449	58.39	4	426	2	420	0.0e+00	656	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
644108499	181	47.13	25	181	1	157	3.0e-58	217	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
644108500	599	55.39	201	599	1	398	0.0e+00	602	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
644108501	224	56.78	17	214	1	194	2.0e-74	271	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
644108502	146	45.9	4	125	1	122	3.0e-33	134	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
644108503	316	28.42	11	281	1	283	1.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
644108504	404	37.38	8	402	1	392	1.0e-97	349	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
644108505	199	40.61	1	195	3	193	3.0e-43	168	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
644108506	610	20.85	21	610	1	458	2.0e-48	187	COG0471	Di- and tricarboxylate transporter	461
644108507	218	38.97	3	210	2	214	3.0e-38	151	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
644108508	164	83.54	1	164	5	168	2.0e-75	274	COG3013	Uncharacterized protein YfbU, UPF0304 family	168
644108509	151	75.84	3	151	1	149	2.0e-61	227	COG3092	Uncharacterized membrane protein YfbV, UPF0208 family	149
644108510	400	55.53	4	399	1	393	0.0e+00	565	COG0282	Acetate kinase	396
644108511	707	56.44	386	706	1	325	3.0e-117	416	COG0280	Phosphotransacetylase	327
644108512	286	63.36	25	286	4	263	1.0e-94	339	COG3739	Uncharacterized membrane protein YoaT, DUF817 family	263
644108513	222	21.19	27	175	1	147	8.0e-07	47.3	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
644108514	183	40.57	1	167	2	158	1.0e-36	145	COG0622	Predicted phosphodiesterase	172
644108515	208	36.54	1	202	1	201	6.0e-39	154	COG0625	Glutathione S-transferase	211
644108516	123	29.31	9	123	4	119	1.0e-21	95.3	COG1539	Dihydroneopterin aldolase	121
644108517	301	53.36	3	300	1	297	1.0e-115	409	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
644108518	257	76.68	1	253	2	253	3.0e-117	414	COG4598	ABC-type histidine transport system, ATPase component	256
644108520	528	38.46	179	517	45	408	7.0e-47	182	COG0840	Methyl-accepting chemotaxis protein	408
644108521	176	60.57	1	175	1	171	6.0e-59	220	COG0221	Inorganic pyrophosphatase	171
644108522	118	48.72	3	114	4	120	2.0e-25	108	COG2105	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family	120
644108523	1345	43.61	25	1345	1	1278	0.0e+00	1025	COG2911	Autotransporter translocation and assembly factor TamB	1278
644108524	613	47.78	36	613	10	594	0.0e+00	577	COG0729	Outer membrane translocation and assembly module TamA	594
644108525	212	54.65	40	211	3	171	3.0e-71	261	COG0225	Peptide methionine sulfoxide reductase MsrA	174
644108526	449	37.56	8	437	2	426	5.0e-103	368	COG1253	Hemolysin or related protein, contains CBS domains	429
644108528	189	63.1	1	187	1	184	8.0e-71	259	COG3054	Predicted transcriptional regulator	184
644108529	246	56.64	1	244	8	262	3.0e-84	304	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
644108530	650	34.8	1	565	2	517	2.0e-118	419	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
644108531	127	42.02	3	121	2	120	2.0e-29	121	COG1733	DNA-binding transcriptional regulator, HxlR family	120
644108532	184	28.85	1	182	3	205	1.0e-21	96.4	COG0655	Multimeric flavodoxin WrbA	207
644108534	555	47.42	2	555	1	557	0.0e+00	634	COG3961	TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase	557
644108535	221	65.16	1	221	1	221	6.0e-89	320	COG2846	Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains	221
644108536	206	50	1	206	1	205	5.0e-63	233	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
644108539	120	49.12	5	117	4	117	4.0e-28	116	COG3189	Uncharacterized conserved protein YeaO, DUF488 family	117
644108540	150	56	1	150	1	148	2.0e-42	164	COG0359	Ribosomal protein L9	148
644108541	75	72.06	1	68	8	75	4.0e-20	89.5	COG0238	Ribosomal protein S18	75
644108543	130	52.68	2	112	1	112	9.0e-36	142	COG0360	Ribosomal protein S6	112
644108544	250	25.09	1	250	22	298	2.0e-16	79.8	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
644108545	646	33.82	329	646	66	408	2.0e-48	187	COG0840	Methyl-accepting chemotaxis protein	408
644108546	373	29.75	1	368	1	432	7.0e-91	327	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
644108547	207	32.21	2	204	1	207	3.0e-49	188	COG1186	Protein chain release factor B	239
644108549	132	56.06	1	132	2	133	2.0e-32	131	COG3766	Uncharacterized membrane protein YjfL, UPF0719 family	133
644108552	243	47.13	1	243	20	258	9.0e-70	256	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
644108553	818	50	15	724	1	706	0.0e+00	765	COG0557	Exoribonuclease R	706
644108554	141	47.01	1	131	1	134	3.0e-34	137	COG1959	DNA-binding transcriptional regulator, IscR family	150
644108555	523	32.8	166	518	31	408	2.0e-41	164	COG0840	Methyl-accepting chemotaxis protein	408
644108556	610	41.99	430	609	1	178	2.0e-38	154	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644108557	338	56.93	1	331	3	333	1.0e-126	446	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
644108558	237	55.6	2	232	1	228	9.0e-84	303	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
644108559	275	43.87	5	272	1	264	2.0e-69	255	COG0345	Pyrroline-5-carboxylate reductase	266
644108560	184	36.46	89	183	1	96	1.0e-06	46.7	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
644108561	96	47	1	96	3	102	8.0e-25	105	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
644108562	197	56.85	1	196	1	192	1.0e-68	252	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
644108563	380	44.82	6	380	34	414	2.0e-119	422	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
644108565	112	34.04	17	109	3	96	1.0e-12	64.7	COG3668	Plasmid stabilization system protein ParE	98
644108568	151	51.97	1	151	1	152	4.0e-49	187	COG2153	Predicted N-acyltransferase, GNAT family	155
644108570	723	30.24	194	713	1	527	2.0e-81	297	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644108571	157	18.9	9	135	4	127	4.0e-09	54.5	COG3153	Predicted N-acetyltransferase YhbS	171
644108572	255	34.62	10	236	9	239	1.0e-43	169	COG2186	DNA-binding transcriptional regulator, FadR family	241
644108573	105	49.52	1	105	1	101	3.0e-27	113	COG1440	Phosphotransferase system cellobiose-specific component IIB	102
644108574	478	37.45	6	474	2	460	5.0e-109	388	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
644108575	445	38.86	3	442	4	432	5.0e-92	331	COG1455	Phosphotransferase system cellobiose-specific component IIC	432
644108576	114	37.62	11	111	4	104	5.0e-21	92.9	COG1447	Phosphotransferase system cellobiose-specific component IIA	105
644108577	337	38.44	3	333	2	333	5.0e-87	314	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644108579	318	22.66	31	282	39	281	6.0e-08	51.8	COG5006	Threonine/homoserine efflux transporter RhtA	292
644108580	420	37.62	1	397	2	394	6.0e-94	338	COG0019	Diaminopimelate decarboxylase	394
644108581	307	29.24	4	300	1	297	4.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
644108582	306	28.81	8	297	7	297	3.0e-32	132	COG0583	DNA-binding transcriptional regulator, LysR family	297
644108583	293	20.66	46	256	30	240	1.0e-19	90.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644108584	218	48.6	4	216	2	212	4.0e-59	221	COG3531	Predicted protein-disulfide isomerase , contains CxxC motif	212
644108585	187	29.51	3	181	9	189	5.0e-24	104	COG4282	Cell wall assembly regulator SMI1	191
644108589	340	37.42	22	331	11	312	3.0e-85	308	COG0042	tRNA-dihydrouridine synthase	323
644108592	462	23.73	7	451	4	402	2.0e-41	164	COG2124	Cytochrome P450	411
644108593	328	42.86	2	327	1	326	3.0e-74	272	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
644108594	468	49.89	22	462	1	435	0.0e+00	561	COG0305	Replicative DNA helicase	435
644108595	360	49.04	1	358	2	360	4.0e-120	424	COG0787	Alanine racemase	360
644108597	159	37.75	1	151	3	152	2.0e-25	108	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644108599	397	58.08	1	396	1	395	0.0e+00	580	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
644108600	165	26.44	1	162	51	220	7.0e-22	97	COG1451	Predicted metal-dependent hydrolase	223
644108606	326	19.4	15	309	1	277	4.0e-46	178	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
644108607	1098	20.62	177	1008	3	668	4.0e-61	230	COG1203	CRISPR/Cas system-associated endonuclease/helicase Cas3	733
644108612	944	69.14	1	942	3	935	0.0e+00	1599	COG0178	Excinuclease UvrABC ATPase subunit	935
644108613	180	46.33	5	180	2	167	3.0e-39	154	COG0629	Single-stranded DNA-binding protein	167
644108614	331	32.74	2	331	1	329	5.0e-65	241	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644108615	476	44.2	21	467	26	477	0.0e+00	479	COG1621	Sucrose-6-phosphate hydrolase SacC, GH32 family	486
644108621	345	31.88	2	344	1	332	1.0e-58	220	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644108622	349	46.19	131	349	59	281	3.0e-55	209	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
644108623	332	42.05	33	332	8	294	9.0e-54	204	COG1175	ABC-type sugar transport system, permease component	295
644108624	363	55.52	1	352	1	338	4.0e-129	454	COG3839	ABC-type sugar transport system, ATPase component	338
644108625	368	43.03	47	359	33	347	2.0e-70	259	COG4225	Rhamnogalacturonyl hydrolase YesR	357
644108631	470	54.19	13	466	5	455	0.0e+00	530	COG1113	L-asparagine transporter and related permeases	462
644108635	218	41.71	2	211	1	211	2.0e-52	199	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644108636	610	51.15	3	608	1	581	0.0e+00	690	COG0322	Excinuclease UvrABC, nuclease subunit	581
644108637	182	41.21	1	181	10	190	4.0e-26	111	COG0558	Phosphatidylglycerophosphate synthase	192
644108641	419	19.75	84	401	1	309	6.0e-11	62.3	COG0582	Integrase	309
644108644	1011	18.27	614	987	48	430	8.0e-09	56.9	COG5002	Signal transduction histidine kinase	459
644108645	390	30.18	1	390	2	326	2.0e-53	203	COG0270	Site-specific DNA-cytosine methylase	328
644108649	291	31.65	1	288	5	300	4.0e-60	225	COG3440	Predicted restriction endonuclease	301
644108652	99	35.11	5	97	4	95	2.0e-08	51.1	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
644108658	769	40.33	1	545	6	550	0.0e+00	554	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
644108659	172	43.6	1	172	1	160	1.0e-49	188	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
644108661	68	38.33	9	67	10	69	4.0e-12	63.4	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
644108664	291	34.83	29	291	30	295	2.0e-45	176	COG3596	Predicted GTPase	296
644108677	384	37.78	206	381	4	181	7.0e-40	158	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644108679	573	42.73	214	532	65	408	2.0e-46	180	COG0840	Methyl-accepting chemotaxis protein	408
644108680	288	23.81	28	279	36	285	2.0e-08	53.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
644108683	295	48.77	1	285	3	266	2.0e-74	272	COG1291	Flagellar motor component MotA	266
644108684	351	38.78	7	267	1	244	1.0e-54	207	COG1360	Flagellar motor protein MotB	244
644108685	671	44.86	1	668	2	716	0.0e+00	663	COG0643	Chemotaxis protein histidine kinase CheA	716
644108686	165	47.2	1	161	3	162	3.0e-38	151	COG0835	Chemotaxis signal transduction protein	165
644108687	561	38	143	517	9	408	7.0e-54	205	COG0840	Methyl-accepting chemotaxis protein	408
644108688	290	52.92	27	289	1	268	1.0e-81	296	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
644108689	350	57.23	3	344	1	345	4.0e-119	421	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
644108691	214	74.38	12	214	15	217	3.0e-77	281	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
644108692	383	50.96	1	363	1	363	2.0e-127	449	COG1377	Flagellar biosynthesis protein FlhB	363
644108693	694	59.03	2	691	1	695	0.0e+00	917	COG1298	Flagellar biosynthesis pathway, component FlhA	696
644108695	145	41.26	1	143	2	144	7.0e-26	109	COG3418	Flagellar biosynthesis/type III secretory pathway chaperone	146
644108696	98	46.24	1	93	1	92	3.0e-11	60	COG2747	Negative regulator of flagellin synthesis (anti-sigma28 factor)	93
644108697	222	36.77	1	221	1	219	3.0e-45	174	COG1261	Flagella basal body P-ring formation protein FlgA	220
644108698	138	50.36	2	137	1	133	3.0e-35	140	COG1815	Flagellar basal body rod protein FlgB	133
644108699	134	64.23	1	134	1	137	4.0e-46	176	COG1558	Flagellar basal body rod protein FlgC	137
644108700	227	42.29	1	227	1	222	9.0e-42	163	COG1843	Flagellar hook assembly protein FlgD	222
644108701	400	45.48	1	400	3	422	3.0e-89	322	COG1749	Flagellar hook protein FlgE	423
644108702	251	68.8	1	250	1	250	5.0e-93	334	COG4787	Flagellar basal body rod protein FlgF	251
644108703	260	53.79	1	260	1	263	5.0e-86	310	COG4786	Flagellar basal body rod protein FlgG	265
644108704	237	53.04	12	234	1	230	9.0e-64	236	COG2063	Flagellar basal body L-ring protein FlgH	230
644108705	369	61.33	8	369	7	365	3.0e-125	441	COG1706	Flagellar basal body P-ring protein FlgI	365
644108706	320	45.71	146	320	33	201	3.0e-45	175	COG1705	Flagellum-specific peptidoglycan hydrolase FlgJ	201
644108707	564	39.12	1	564	3	552	9.0e-99	354	COG1256	Flagellar hook-associated protein FlgK	552
644108708	317	21.91	1	315	1	355	2.0e-30	126	COG1344	Flagellin and related hook-associated protein FlgL	360
644108709	261	50.78	2	259	1	258	5.0e-49	188	COG1684	Flagellar biosynthesis protein FliR	258
644108710	89	56.18	1	89	1	89	3.0e-19	87.1	COG1987	Flagellar biosynthesis protein FliQ	89
644108711	258	56.68	11	257	2	248	6.0e-77	280	COG1338	Flagellar biosynthetic protein FliP	248
644108712	112	46.43	3	112	24	135	5.0e-23	99.6	COG3190	Flagellar biogenesis protein FliO	137
644108713	137	45.74	1	125	8	136	6.0e-25	106	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
644108714	337	51.34	1	333	1	330	2.0e-101	362	COG1868	Flagellar motor switch protein FliM	332
644108715	159	32.5	1	159	5	159	1.0e-30	125	COG1580	Flagellar basal body-associated protein FliL	159
644108716	431	24.24	8	431	8	417	1.0e-21	97.8	COG3144	Flagellar hook-length control protein FliK	417
644108717	148	43.92	1	148	1	148	5.0e-17	80.3	COG2882	Flagellar biosynthesis chaperone FliJ	148
644108718	456	59.56	4	453	1	440	0.0e+00	626	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
644108719	241	33.9	8	241	13	229	9.0e-36	143	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
644108720	330	52.27	1	330	9	339	3.0e-90	325	COG1536	Flagellar motor switch protein FliG	339
644108721	574	42.66	12	573	9	545	0.0e+00	475	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
644108722	104	45.28	1	104	2	105	7.0e-15	72.3	COG1677	Flagellar hook-basal body complex protein FliE	105
644108724	136	46.51	1	129	1	124	3.0e-34	137	COG1516	Flagellin-specific chaperone FliS	132
644108725	474	34.42	1	474	3	480	4.0e-61	229	COG1345	Flagellar capping protein FliD	483
644108726	290	31.01	3	289	2	277	2.0e-24	106	COG1344	Flagellin and related hook-associated protein FlgL	360
644108727	1087	27.66	480	1049	10	593	7.0e-68	252	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
644108728	370	40.17	16	365	15	367	3.0e-89	322	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
644108735	230	45.89	1	229	23	247	1.0e-58	219	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
644108737	262	45.56	4	262	81	329	2.0e-77	282	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
644108738	381	46.33	1	380	67	460	1.0e-99	356	COG1109	Phosphomannomutase	464
644108739	110	52.27	1	88	1	85	7.0e-16	75.6	COG1314	Preprotein translocase subunit SecG	86
644108741	338	44.61	6	338	9	338	2.0e-93	335	COG2130	NADPH-dependent curcumin reductase CurA	340
644108743	1357	34.4	275	921	1	640	2.0e-126	447	COG1020	Non-ribosomal peptide synthetase component F	642
644108744	1833	41.03	8	885	2	874	0.0e+00	781	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
644108751	153	47.3	7	150	6	151	3.0e-35	141	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
644108753	204	26.7	1	201	1	206	2.0e-27	115	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644108755	150	55.63	1	150	3	153	5.0e-49	186	COG0779	Ribosome maturation factor RimP	153
644108756	509	48.02	164	364	2	190	2.0e-48	187	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
644108757	899	66.07	397	899	2	508	0.0e+00	696	COG0532	Translation initiation factor IF-2, a GTPase	509
644108758	132	48.74	1	119	1	117	5.0e-31	126	COG0858	Ribosome-binding factor A	118
644108759	314	38.91	1	311	4	271	8.0e-72	264	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
644108760	89	61.8	1	89	1	89	2.0e-28	117	COG0184	Ribosomal protein S15P/S13E	89
644108761	706	66.04	1	692	1	690	0.0e+00	1026	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
644108762	294	82.15	1	294	1	297	9.0e-127	446	COG4785	Lipoprotein NlpI, contains TPR repeats	297
644108763	627	43.22	5	471	28	503	6.0e-124	438	COG0513	Superfamily II DNA and RNA helicase	513
644108764	333	25.24	31	331	20	333	6.0e-44	171	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
644108765	292	25.24	2	290	1	302	2.0e-52	199	COG0826	Collagenase-like protease, PrtC family	347
644108766	331	37.39	1	331	7	312	1.0e-84	307	COG0826	Collagenase-like protease, PrtC family	347
644108767	174	57.14	6	166	1	160	2.0e-48	185	COG3154	Predicted lipid carrier protein YhbT, SCP2 domain	168
644108768	180	46.41	1	179	4	171	2.0e-38	151	COG3153	Predicted N-acetyltransferase YhbS	171
644108769	99	50	6	89	1	84	8.0e-24	101	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
644108770	492	24.89	34	460	1	392	5.0e-54	205	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
644108771	259	39.75	4	242	1	216	1.0e-56	213	COG0274	Deoxyribose-phosphate aldolase	228
644108773	442	51.94	1	439	1	435	0.0e+00	545	COG0213	Thymidine phosphorylase	435
644108774	407	63.64	1	407	1	393	0.0e+00	611	COG1015	Phosphopentomutase	397
644108775	239	71.19	1	236	1	236	4.0e-111	394	COG0813	Purine-nucleoside phosphorylase	236
644108776	582	38.3	2	547	24	586	0.0e+00	475	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
644108777	831	42.61	137	831	57	719	0.0e+00	584	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
644108778	320	38.49	8	320	13	322	2.0e-58	219	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
644108779	180	28.65	7	175	12	182	2.0e-24	105	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644108782	147	30.3	1	146	11	173	3.0e-18	84.7	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
644108783	137	61.36	3	133	2	133	9.0e-38	148	COG3050	DNA polymerase III, psi subunit	133
644108784	349	48.15	40	334	1	297	9.0e-92	330	COG2813	16S rRNA G1207 methylase RsmC	300
644108785	330	45.65	1	318	1	316	6.0e-92	331	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
644108786	305	32.45	8	304	3	297	1.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
644108791	300	34.98	1	300	1	297	8.0e-40	157	COG0583	DNA-binding transcriptional regulator, LysR family	297
644108792	260	42.92	27	259	2	234	5.0e-70	257	COG3527	Alpha-acetolactate decarboxylase	234
644108793	559	35.54	12	550	3	539	4.0e-129	455	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
644108794	487	22.67	79	323	1	211	7.0e-19	88.9	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
644108795	383	45.95	3	383	2	377	6.0e-114	404	COG1454	Alcohol dehydrogenase, class IV	377
644108796	371	46.75	1	367	4	375	1.0e-103	370	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
644108797	130	58.46	1	129	2	131	1.0e-41	161	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
644108798	957	65.03	471	925	28	490	0.0e+00	738	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
644108799	156	23.94	1	130	2	138	2.0e-06	45.3	COG1247	L-amino acid N-acyltransferase YncA	169
644108800	290	36.21	1	290	6	295	9.0e-53	200	COG1175	ABC-type sugar transport system, permease component	295
644108801	301	36.75	24	301	1	281	7.0e-51	194	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
644108802	274	25.19	1	250	1	251	2.0e-25	109	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
644108803	362	50.29	1	350	1	338	8.0e-116	410	COG3839	ABC-type sugar transport system, ATPase component	338
644108804	435	27.04	6	425	13	433	5.0e-37	149	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
644108806	714	38.1	4	694	2	687	0.0e+00	658	COG3345	Alpha-galactosidase	687
644108807	334	30.03	1	330	1	328	2.0e-59	223	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644108808	202	27.4	12	153	1	145	2.0e-13	69.3	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
644108809	215	56.46	10	215	16	223	5.0e-49	187	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
644108810	333	37.15	12	333	1	305	3.0e-70	258	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
644108811	88	48.24	1	85	10	94	1.0e-23	101	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
644108813	311	60.49	31	311	2	287	9.0e-116	410	COG3129	23S rRNA A1618 N6-methylase RlmF	292
644108815	172	33.53	1	168	2	151	2.0e-29	122	COG0716	Flavodoxin	151
644108816	128	23.85	1	127	5	132	3.0e-13	67.2	COG0824	Acyl-CoA thioesterase FadM	137
644108817	442	20.83	73	431	71	431	8.0e-10	58.7	COG2271	Sugar phosphate permease	448
644108818	299	62.46	1	299	1	300	7.0e-118	416	COG4974	Site-specific recombinase XerD	300
644108819	238	28.4	1	232	4	244	1.0e-33	136	COG1651	Protein-disulfide isomerase	244
644108820	584	42.99	37	561	4	491	4.0e-114	405	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
644108821	293	65.27	56	293	1	239	5.0e-102	364	COG1186	Protein chain release factor B	239
644108822	505	63	9	505	4	502	0.0e+00	757	COG1190	Lysyl-tRNA synthetase (class II)	502
644108823	251	30.43	135	248	6	120	5.0e-19	88.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644108824	227	23.96	1	215	2	207	1.0e-09	56.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644108826	132	32	4	128	8	132	4.0e-24	103	COG4319	Ketosteroid isomerase homolog	137
644108828	307	50.99	7	307	6	308	6.0e-90	324	COG1560	Lauroyl/myristoyl acyltransferase	308
644108831	465	20.62	8	424	13	372	1.0e-12	67.9	COG2814	Predicted arabinose efflux permease, MFS family	394
644108832	455	36.72	153	455	35	333	3.0e-42	166	COG0642	Signal transduction histidine kinase	336
644108833	242	45.18	13	238	3	229	6.0e-62	230	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644108834	217	26.74	6	185	4	190	3.0e-25	108	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
644108835	183	37.22	7	181	1	180	5.0e-29	120	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644108836	319	51.69	1	312	1	324	2.0e-115	409	COG0435	Glutathionyl-hydroquinone reductase	324
644108837	453	42.2	1	389	4	347	1.0e-112	400	COG0826	Collagenase-like protease, PrtC family	347
644108838	299	38.69	1	298	2	301	3.0e-66	245	COG1597	Diacylglycerol kinase family enzyme	301
644108839	135	70.4	11	135	13	137	4.0e-33	133	COG3223	Phosphate starvation-inducible membrane PsiE (function unknown)	138
644108840	267	54.31	1	267	1	263	3.0e-97	348	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
644108841	264	51.75	11	264	1	257	9.0e-75	273	COG2145	Hydroxyethylthiazole kinase, sugar kinase family	265
644108842	339	34.8	1	339	1	339	5.0e-96	344	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
644108843	307	29.94	133	299	5	181	2.0e-31	129	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644108844	230	31.17	1	228	23	252	3.0e-14	72.4	COG0730	Uncharacterized membrane protein YfcA	258
644108845	323	32.08	30	320	1	289	8.0e-38	151	COG0583	DNA-binding transcriptional regulator, LysR family	297
644108851	489	22.68	34	293	55	292	7.0e-17	82.4	COG0790	TPR repeat	292
644108852	114	44.23	2	105	8	107	2.0e-24	104	COG4679	Phage-related protein	116
644108853	105	30.43	1	92	1	91	2.0e-10	57.3	COG5606	Predicted DNA-binding protein, XRE-type HTH domain	91
644108854	71	79.37	5	67	7	69	9.0e-22	95.1	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
644108855	114	50	33	112	20	99	4.0e-22	96.5	COG3657	Putative component of the toxin-antitoxin plasmid stabilization module	100
644108856	112	39.58	12	107	4	94	6.0e-20	89.2	COG3636	DNA-binding prophage protein	100
644108857	239	26.53	51	237	6	201	3.0e-10	59.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644108858	307	38.96	1	304	1	324	7.0e-60	224	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
644108859	292	32.47	15	288	9	308	3.0e-53	202	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
644108860	525	43.69	8	206	2	198	2.0e-59	223	COG0518	GMP synthase - Glutamine amidotransferase domain	198
644108860	525	68.03	207	525	1	315	0.0e+00	560	COG0519	GMP synthase, PP-ATPase domain/subunit	315
644108861	488	30.91	257	476	1	170	4.0e-34	139	COG0516	IMP dehydrogenase/GMP reductase	170
644108862	438	55.32	1	423	23	440	0.0e+00	516	COG1570	Exonuclease VII, large subunit	440
644108866	147	48.89	1	135	4	138	2.0e-34	138	COG4101	Uncharacterized protein, RmlC-like cupin domain	142
644108867	319	29.68	6	313	2	307	2.0e-36	146	COG0679	Predicted permease	311
644108868	495	53.16	1	471	2	444	0.0e+00	585	COG1160	Predicted GTPases	444
644108869	393	28.43	1	390	4	368	3.0e-52	199	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
644108870	206	52.66	1	206	1	207	2.0e-49	188	COG2976	Putative negative regulator of RcsB-dependent stress response	207
644108871	424	50	2	424	1	429	0.0e+00	518	COG0124	Histidyl-tRNA synthetase	429
644108872	373	63.06	7	366	1	360	0.0e+00	540	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
644108873	332	38.57	12	298	1	284	4.0e-48	185	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
644108874	251	42.04	9	250	6	250	9.0e-56	210	COG3063	Tfp pilus assembly protein PilF	250
644108875	418	56.9	51	402	1	349	0.0e+00	479	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
644108877	142	61.94	3	136	2	135	2.0e-55	208	COG0105	Nucleoside diphosphate kinase	135
644108878	526	33.09	18	423	22	388	2.0e-54	207	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
644108879	453	36.42	3	446	1	442	9.0e-120	424	COG1486	Alpha-galactosidase/6-phospho-beta-glucosidase, family 4 of glycosyl hydrolase	442
644108880	289	43.86	5	288	2	282	3.0e-78	285	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
644108881	262	26.91	1	221	2	224	3.0e-31	128	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
644108883	435	39.07	1	435	23	485	4.0e-123	435	COG0260	Leucyl aminopeptidase	485
644108884	66	76.56	3	66	1	64	2.0e-22	97.3	COG2975	Fe-S-cluster formation regulator IscX/YfhJ	64
644108885	111	46.23	1	104	1	102	1.0e-19	88.2	COG0633	Ferredoxin	102
644108886	616	46.74	18	602	4	579	0.0e+00	542	COG0443	Molecular chaperone DnaK (HSP70)	579
644108887	172	39.53	1	171	1	172	7.0e-26	110	COG1076	DnaJ-domain-containing proteins 1	174
644108888	107	57.41	1	107	3	110	4.0e-36	142	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
644108889	128	53.47	1	125	5	145	4.0e-37	146	COG0822	NifU homolog involved in Fe-S cluster formation	150
644108890	404	63.43	3	388	1	386	0.0e+00	577	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
644108891	164	43.06	1	143	1	144	1.0e-39	155	COG1959	DNA-binding transcriptional regulator, IscR family	150
644108892	241	54.43	1	237	1	234	6.0e-87	313	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
644108893	267	50.38	1	258	1	260	8.0e-82	296	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
644108894	372	26.14	1	340	1	317	2.0e-36	146	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
644108895	360	44.05	28	360	2	333	3.0e-53	202	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
644108896	266	37.94	9	257	3	254	5.0e-64	237	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
644108898	555	33.08	140	510	8	406	1.0e-43	171	COG0840	Methyl-accepting chemotaxis protein	408
644108900	375	24.55	15	344	26	319	2.0e-40	160	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
644108901	366	35.12	21	356	2	303	2.0e-61	229	COG2215	ABC-type nickel/cobalt efflux system, permease component RcnA	303
644108902	219	47.14	10	218	4	213	6.0e-65	240	COG3683	ABC-type uncharacterized transport system, periplasmic component	213
644108904	417	69.73	5	416	4	412	0.0e+00	692	COG0112	Glycine/serine hydroxymethyltransferase	413
644108905	396	59.33	1	148	1	150	1.0e-57	217	COG1017	Hemoglobin-like flavoprotein	150
644108907	368	29.27	17	360	65	405	9.0e-64	237	COG4677	Pectin methylesterase and related acyl-CoA thioesterases	405
644108908	112	75	1	112	1	112	4.0e-40	156	COG0347	Nitrogen regulatory protein PII	112
644108909	445	45.45	3	444	1	462	0.0e+00	487	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644108911	478	30.42	151	478	14	334	5.0e-35	142	COG0642	Signal transduction histidine kinase	336
644108912	1295	38.88	158	967	1	733	0.0e+00	784	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
644108913	502	62.28	42	495	1	456	0.0e+00	626	COG4623	Membrane-bound lytic murein transglycosylase MltF	473
644108914	168	60.69	6	149	7	151	2.0e-50	192	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
644108915	212	21.9	5	211	3	194	4.0e-26	111	COG0560	Phosphoserine phosphatase	212
644108916	308	67.58	13	305	1	293	3.0e-118	418	COG2103	N-acetylmuramic acid 6-phosphate (MurNAc-6-P) etherase	298
644108918	650	27.57	410	647	1	242	4.0e-35	143	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644108921	149	49.32	4	149	1	145	4.0e-37	147	COG1934	Lipopolysaccharide export system protein LptA	173
644108922	188	45.74	2	188	1	187	4.0e-47	181	COG3117	Lipopolysaccharide export system protein LptC	188
644108923	188	61.18	19	188	1	170	3.0e-65	240	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
644108924	363	57.92	47	247	1	202	1.0e-70	260	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
644108925	321	50	1	318	8	318	3.0e-59	222	COG0530	Ca2+/Na+ antiporter	320
644108926	270	58.02	1	261	1	262	8.0e-105	373	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
644108927	260	50.38	1	260	7	265	2.0e-72	265	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
644108929	209	56.22	1	199	3	202	2.0e-65	241	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
644108930	96	45.92	1	95	1	98	9.0e-19	84.9	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
644108931	84	73.75	1	80	1	80	3.0e-31	126	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
644108932	420	66.9	1	418	1	420	0.0e+00	657	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
644108933	365	39.82	39	365	27	344	4.0e-60	225	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
644108934	456	46.83	7	368	1	347	1.0e-77	284	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
644108935	134	71.88	1	128	6	133	5.0e-49	186	COG3105	Uncharacterized membrane-anchored protein YhcB, DUF1043 family	138
644108936	383	49.87	4	382	2	367	0.0e+00	462	COG1485	Predicted ATPase	367
644108937	142	64.34	1	142	1	143	1.0e-56	211	COG0102	Ribosomal protein L13	148
644108938	130	67.69	1	130	1	130	2.0e-48	184	COG0103	Ribosomal protein S9	130
644108939	442	20.15	61	440	65	447	7.0e-11	62.1	COG2271	Sugar phosphate permease	448
644108940	348	32.95	10	348	4	350	5.0e-63	234	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
644108941	257	36.86	7	254	1	251	4.0e-45	175	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644108942	234	29.6	4	222	3	225	5.0e-41	160	COG2186	DNA-binding transcriptional regulator, FadR family	241
644108943	414	30.29	20	397	32	371	2.0e-62	233	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644108944	213	36.19	11	206	1	208	5.0e-32	131	COG0625	Glutathione S-transferase	211
644108945	167	63.64	3	167	2	155	8.0e-53	199	COG2969	Stringent starvation protein B	155
644108946	257	42.41	5	255	7	251	1.0e-43	170	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644108947	472	47.03	24	470	2	450	0.0e+00	503	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
644108948	1486	59.26	692	1174	1	485	0.0e+00	655	COG0069	Glutamate synthase domain 2	485
644108949	309	53.7	1	306	2	311	4.0e-123	434	COG1242	Radical SAM superfamily enzyme	312
644108951	217	69.59	1	217	1	217	6.0e-90	323	COG3155	Enhancing lycopene biosynthesis protein 2	217
644108954	190	53.12	1	190	5	196	2.0e-42	165	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
644108955	196	65.92	1	179	1	176	6.0e-65	240	COG0279	Phosphoheptose isomerase	176
644108958	673	48.96	1	672	1	603	0.0e+00	539	COG3107	Outer membrane lipoprotein LpoA, binds and activates PBP1a	604
644108959	295	58.63	8	285	1	275	2.0e-104	372	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
644108960	261	54.14	1	261	3	267	2.0e-88	318	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
644108961	386	64.52	1	386	1	387	0.0e+00	561	COG0754	Glutathionylspermidine synthase	387
644108962	224	44.71	1	207	2	196	2.0e-50	192	COG5463	Uncharacterized conserved protein YgiB, involved in bioifilm formation, UPF0441/DUF1190 family	198
644108963	463	31.82	25	436	45	455	8.0e-50	191	COG1538	Outer membrane protein TolC	457
644108965	143	70.5	1	139	6	144	5.0e-54	203	COG3151	Uncharacterized protein YqiB, DUF1249 family	147
644108966	275	35.25	15	275	1	270	3.0e-38	152	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
644108967	193	51.6	3	190	1	188	2.0e-71	261	COG3150	Predicted esterase YcpF, UPF0227 family	191
644108968	631	48.28	1	629	1	632	0.0e+00	877	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
644108970	286	43.71	1	283	2	286	3.0e-88	318	COG0191	Fructose/tagatose bisphosphate aldolase	286
644108971	283	38.54	1	283	2	286	7.0e-61	227	COG0191	Fructose/tagatose bisphosphate aldolase	286
644108972	363	46.36	11	346	1	343	5.0e-79	288	COG1299	Phosphotransferase system, fructose-specific IIC component	343
644108973	104	52.94	1	102	2	103	2.0e-25	107	COG1445	Phosphotransferase system fructose-specific component IIB	122
644108974	159	34.64	2	153	1	152	1.0e-26	112	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
644108975	516	20.89	5	513	2	472	2.0e-33	137	COG3711	Transcriptional antiterminator	491
644108976	551	61.82	13	549	1	522	0.0e+00	550	COG1620	L-lactate permease	522
644108977	258	42.68	3	239	6	241	2.0e-48	186	COG2186	DNA-binding transcriptional regulator, FadR family	241
644108978	377	45.14	8	376	3	349	5.0e-106	378	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
644108979	756	42.89	1	745	1	747	0.0e+00	791	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
644108980	245	32.92	5	238	1	236	5.0e-36	144	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
644108981	471	39.29	5	468	1	449	1.0e-83	303	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
644108982	224	35.87	1	220	10	232	2.0e-42	166	COG2188	DNA-binding transcriptional regulator, GntR family	236
644108983	275	46.21	1	270	1	276	2.0e-95	342	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
644108984	387	64.86	1	387	1	384	0.0e+00	585	COG1979	Alcohol dehydrogenase YqhD, Fe-dependent ADH family	384
644108985	246	31.55	1	186	2	207	6.0e-25	107	COG0778	Nitroreductase	207
644108987	336	36.22	205	331	1	127	1.0e-22	101	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644108988	219	36.08	25	217	13	206	1.0e-31	130	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
644108989	396	36.29	7	395	9	396	5.0e-114	404	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
644108990	430	55.38	46	426	1	379	3.0e-103	369	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
644108991	168	26.95	1	167	1	166	4.0e-22	97.7	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
644108992	325	38.25	1	325	2	330	6.0e-84	304	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
644108993	239	42.13	10	222	1	216	3.0e-43	168	COG0811	Biopolymer transport protein ExbB/TolQ	216
644108994	141	48.46	10	139	8	137	4.0e-35	140	COG0848	Biopolymer transport protein ExbD	137
644108995	339	34.73	7	338	1	331	1.0e-65	243	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644108996	460	44.28	9	456	20	486	9.0e-127	447	COG1621	Sucrose-6-phosphate hydrolase SacC, GH32 family	486
644108997	456	32.53	95	452	1	375	2.0e-68	253	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
644108998	511	23.71	81	511	16	429	1.0e-30	128	COG4580	Maltoporin (phage lambda and maltose receptor)	429
644109002	378	18.44	1	378	1	388	1.0e-06	47.6	COG3966	Poly D-alanine transfer protein DltD, involved inesterification of teichoic acids	415
644109004	297	35.93	5	294	2	288	7.0e-38	151	COG0583	DNA-binding transcriptional regulator, LysR family	297
644109005	146	33.86	14	138	6	131	3.0e-18	84.5	COG1917	Cupin domain protein related to quercetin dioxygenase	131
644109006	107	38.61	1	100	3	103	5.0e-18	82.5	COG1447	Phosphotransferase system cellobiose-specific component IIA	105
644109007	338	25.99	47	338	1	299	2.0e-40	159	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
644109008	525	33.27	16	509	2	522	6.0e-64	238	COG1178	ABC-type Fe3+ transport system, permease component	540
644109009	356	36.26	1	354	5	350	4.0e-87	315	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644109012	556	36.11	1	527	1	535	2.0e-64	240	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
644109013	297	16.97	1	271	19	261	8.0e-12	64.7	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
644109014	677	39.24	1	305	2	305	2.0e-82	300	COG0223	Methionyl-tRNA formyltransferase	307
644109015	327	33.45	4	280	1	275	2.0e-22	100	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
644109016	382	47.78	1	380	2	374	3.0e-125	441	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
644109017	388	39.95	1	375	1	392	6.0e-122	431	COG1004	UDP-glucose 6-dehydrogenase	414
644109019	287	57.65	4	284	1	281	5.0e-113	400	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
644109020	70	41.43	1	70	1	70	1.0e-18	84.5	COG2501	Ribosome-associated protein YbcJ, S4-like RNA binding protein	73
644109021	461	60.09	1	461	1	464	0.0e+00	709	COG0215	Cysteinyl-tRNA synthetase	464
644109022	143	26.61	15	136	12	133	1.0e-07	48.8	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
644109023	164	50.6	1	164	1	158	8.0e-52	196	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
644109024	240	52.92	4	240	1	236	2.0e-72	265	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
644109025	169	63.19	7	169	2	162	4.0e-61	227	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
644109026	356	43.54	1	350	1	375	3.0e-116	411	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
644109027	429	38.41	17	429	7	415	8.0e-75	274	COG0814	Amino acid permease	415
644109028	455	50.18	170	450	1	262	5.0e-91	328	COG1760	L-serine deaminase	262
644109030	271	65.35	18	271	1	253	5.0e-122	430	COG1117	ABC-type phosphate transport system, ATPase component	253
644109031	548	34.88	1	279	8	288	9.0e-70	258	COG4985	ABC-type phosphate transport system, auxiliary component	289
644109032	702	43.84	2	698	22	733	0.0e+00	662	COG4590	ABC-type uncharacterized transport system, permease component	733
644109033	690	51.3	2	685	6	692	0.0e+00	869	COG0855	Polyphosphate kinase	696
644109034	511	46.56	12	499	1	492	0.0e+00	507	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
644109036	81	58.97	4	81	1	77	1.0e-19	88.1	COG5639	Uncharacterized protein	77
644109037	425	32.6	13	419	1	360	4.0e-61	229	COG2948	Type IV secretory pathway, VirB10 components	360
644109038	334	39.43	52	327	1	251	3.0e-57	215	COG3504	Type IV secretory pathway, VirB9 components	265
644109039	234	64.04	1	228	1	228	1.0e-89	322	COG3701	Type IV secretory pathway, TrbF components	228
644109040	463	39.78	1	458	27	452	5.0e-78	285	COG3846	Type IV secretory pathway, TrbL components	452
644109042	247	50.62	7	247	12	252	9.0e-55	206	COG5314	Conjugal transfer/entry exclusion protein	252
644109043	816	37.19	1	797	3	796	0.0e+00	704	COG3451	Type IV secretory pathway, VirB4 component	796
644109044	89	47.06	7	88	8	92	8.0e-26	108	COG5268	Type IV secretory pathway, TrbD component	93
644109045	128	48.15	22	128	3	108	2.0e-16	78	COG3838	Type IV secretory pathway, VirB2 components (pilins)	108
644109046	356	42.54	21	327	38	348	2.0e-84	306	COG4962	Pilus assembly protein, ATPase of CpaF family	355
644109048	668	40	1	575	4	579	0.0e+00	598	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
644109050	314	34.24	1	291	1	289	4.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
644109052	206	27.27	53	195	42	181	7.0e-10	57.7	COG3506	Regulation of enolase protein 1 (function unknown), concanavalin A-like superfamily	189
644109053	393	20.69	21	377	22	397	7.0e-17	82.2	COG0738	Fucose permease	422
644109054	897	35.95	9	882	107	933	0.0e+00	831	COG0178	Excinuclease UvrABC ATPase subunit	935
644109055	394	46.53	1	388	11	394	2.0e-68	253	COG2814	Predicted arabinose efflux permease, MFS family	394
644109056	234	28.9	1	217	1	202	4.0e-36	144	COG1182	FMN-dependent NADH-azoreductase	202
644109057	307	27.21	9	296	1	292	2.0e-30	126	COG0583	DNA-binding transcriptional regulator, LysR family	297
644109058	662	46.25	74	390	1	320	5.0e-74	272	COG3843	Type IV secretory pathway, VirD2 components (relaxase)	326
644109060	199	53.89	19	198	2	173	3.0e-47	181	COG4959	Type IV secretory pathway, protease TraF	173
644109063	212	30.28	1	210	3	253	3.0e-30	125	COG1192	Cellulose biosynthesis protein BcsQ	259
644109065	282	55.05	1	279	7	312	1.0e-80	293	COG5534	Plasmid replication initiator protein	383
644109067	268	36.2	87	248	1	160	5.0e-22	98.2	COG5419	Uncharacterized protein	160
644109069	96	38.46	29	80	6	57	4.0e-08	49.4	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
644109071	104	56.19	1	103	3	107	2.0e-34	136	COG5489	Uncharacterized conserved protein, DUF736 family	107
644109078	575	25.36	138	555	141	519	9.0e-28	118	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
644109080	286	47.53	46	207	1	159	1.0e-48	186	COG4804	Predicted nuclease of restriction endonuclease-like (RecB) superfamily,  DUF1016 family	159
644109083	450	21.15	21	430	41	453	3.0e-38	153	COG1538	Outer membrane protein TolC	457
644109084	744	32.75	45	733	12	696	0.0e+00	525	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
644109086	504	43.02	321	498	4	181	2.0e-43	170	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644109087	211	23.85	2	205	34	246	1.0e-22	99.6	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644109089	126	48.8	2	126	1	125	2.0e-37	147	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
644109090	243	69.96	4	243	1	243	2.0e-97	348	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
644109091	245	42.21	5	239	8	251	2.0e-54	205	COG1381	Recombinational DNA repair protein (RecF pathway)	251
644109092	301	55.22	5	300	3	298	1.0e-119	422	COG1159	GTPase Era, involved in 16S rRNA processing	298
644109093	226	55.02	1	224	3	230	3.0e-78	284	COG0571	dsRNA-specific ribonuclease	235
644109095	599	70.74	1	597	6	603	0.0e+00	1082	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
644109096	150	52.38	1	147	1	147	1.0e-41	162	COG3086	Positive regulator of sigma E activity	150
644109097	320	52.02	1	318	1	318	6.0e-98	350	COG3026	Negative regulator of sigma E activity	320
644109098	215	57.55	1	210	5	213	2.0e-51	195	COG3073	Negative regulator of sigma E activity	213
644109099	191	36.56	7	191	2	181	6.0e-32	130	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644109100	533	57.79	1	532	1	509	0.0e+00	720	COG0029	Aspartate oxidase	518
644109101	248	35.1	8	248	5	248	2.0e-58	218	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
644109102	441	43.24	1	439	26	466	1.0e-108	387	COG0513	Superfamily II DNA and RNA helicase	513
644109103	127	82.68	1	127	1	127	1.0e-60	224	COG3445	Autonomous glycyl radical cofactor GrcA	127
644109104	228	68.02	1	222	1	222	3.0e-106	377	COG0692	Uracil DNA glycosylase	223
644109107	360	30.11	96	355	1	255	1.0e-46	180	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
644109108	471	43.43	2	463	9	472	0.0e+00	512	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
644109113	368	36.91	1	357	1	340	5.0e-78	284	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
644109114	144	26.67	5	137	1	133	4.0e-07	47.7	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
644109115	330	53.87	1	325	1	340	6.0e-111	394	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
644109116	293	58.87	6	287	5	286	3.0e-102	364	COG4208	ABC-type sulfate transport system, permease component	287
644109117	270	55.22	1	265	1	268	1.0e-68	253	COG0555	ABC-type sulfate transport system, permease component	274
644109118	336	66.67	6	332	19	345	0.0e+00	511	COG1613	ABC-type sulfate transport system, periplasmic component	348
644109119	385	59.58	5	385	2	376	2.0e-126	445	COG3835	Sugar diacid utilization regulator	376
644109120	482	43.75	6	388	2	340	7.0e-71	261	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
644109121	503	31.96	2	503	1	412	8.0e-92	331	COG0232	dGTP triphosphohydrolase	412
644109122	232	55.6	1	230	3	234	4.0e-63	234	COG0775	Nucleoside phosphorylase	234
644109123	276	26.62	22	265	52	312	2.0e-32	133	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
644109126	115	59.09	6	115	1	110	1.0e-38	151	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
644109127	426	66.35	3	426	6	429	0.0e+00	638	COG0001	Glutamate-1-semialdehyde aminotransferase	432
644109128	207	31.88	2	204	1	204	6.0e-30	124	COG0625	Glutathione S-transferase	211
644109129	488	36	7	477	1	456	5.0e-93	335	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644109130	196	23.38	5	192	8	208	1.0e-14	73.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644109131	672	43.26	398	672	50	331	3.0e-44	173	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
644109132	308	26.42	36	292	43	301	2.0e-27	116	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
644109133	265	46.85	10	263	1	254	2.0e-86	312	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
644109134	825	38.82	131	807	5	648	0.0e+00	560	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
644109135	820	42.05	5	818	50	845	0.0e+00	712	COG1643	HrpA-like RNA helicase	845
644109136	176	34.83	6	174	2	178	3.0e-34	138	COG1514	2'-5' RNA ligase	180
644109137	234	54.74	1	232	1	228	5.0e-83	300	COG1489	DNA-binding protein, stimulates sugar fermentation	235
644109138	151	55	32	151	1	120	3.0e-29	121	COG1734	RNA polymerase-binding transcription factor DksA	120
644109140	452	38.82	21	442	2	412	5.0e-100	358	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
644109141	177	56.96	3	160	2	158	3.0e-54	204	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
644109142	265	58.87	3	265	1	264	1.0e-105	376	COG0413	Ketopantoate hydroxymethyltransferase	268
644109143	284	57.04	1	282	1	284	3.0e-111	394	COG0414	Panthothenate synthetase	285
644109144	126	59.2	2	126	1	125	5.0e-51	192	COG0853	Aspartate 1-decarboxylase	126
644109145	256	19.13	18	247	35	252	2.0e-09	56.3	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
644109146	312	37.29	1	302	1	293	9.0e-74	270	COG1131	ABC-type multidrug transport system, ATPase component	293
644109147	213	49.51	1	202	1	206	8.0e-64	236	COG0288	Carbonic anhydrase	207
644109148	178	63.64	1	176	3	176	1.0e-70	258	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
644109151	361	36.36	7	347	5	352	7.0e-88	317	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644109152	540	28.81	1	534	7	530	2.0e-56	213	COG1178	ABC-type Fe3+ transport system, permease component	540
644109154	287	52.48	4	284	2	281	1.0e-95	343	COG0421	Spermidine synthase	282
644109155	264	42.78	3	181	1	135	4.0e-37	148	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
644109157	79	26.25	1	76	1	80	2.0e-12	63.8	COG0695	Glutaredoxin	80
644109158	135	64.93	1	134	1	134	5.0e-55	206	COG1780	Protein involved in ribonucleotide reduction	141
644109159	693	38.78	1	692	24	654	0.0e+00	650	COG0209	Ribonucleotide reductase alpha subunit	696
644109160	320	48.17	7	320	24	348	8.0e-103	367	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
644109162	245	37.14	1	242	8	240	9.0e-46	176	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
644109163	154	64.71	3	152	2	154	3.0e-54	204	COG0328	Ribonuclease HI	154
644109165	251	30.68	4	222	17	252	9.0e-26	110	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644109166	457	24.23	61	242	52	278	4.0e-09	56.3	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
644109170	265	61.66	1	251	5	256	4.0e-87	314	COG3228	Mlc titration factor MtfA, regulates ptsG expression	266
644109171	128	37.61	5	120	11	127	1.0e-22	98.5	COG3755	Uncharacterized conserved protein YecT, DUF1311 family	127
644109172	55	60.38	1	52	4	56	2.0e-09	53.6	COG0401	Uncharacterized membrane protein YqaE, homolog of Blt101, UPF0057 family	56
644109173	490	41.67	322	487	13	179	7.0e-43	168	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644109174	300	39.46	13	299	4	296	5.0e-59	221	COG1597	Diacylglycerol kinase family enzyme	301
644109175	199	63.32	1	199	2	200	4.0e-81	293	COG3560	Fatty acid repression mutant protein (predicted oxidoreductase)	200
644109176	251	49.8	2	248	1	253	4.0e-71	261	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
644109177	411	46.38	7	406	5	402	4.0e-130	458	COG0303	Molybdopterin biosynthesis enzyme	404
644109178	633	55.34	25	586	5	539	0.0e+00	686	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
644109179	514	33.81	1	514	2	554	1.0e-87	317	COG0747	ABC-type transport system, periplasmic component	556
644109180	306	51.43	1	305	1	315	1.0e-92	333	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644109181	301	49.82	22	301	8	288	6.0e-75	274	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644109182	565	35.47	50	561	1	432	9.0e-130	457	COG0281	Malic enzyme	432
644109183	296	40.77	52	172	7	134	1.0e-30	127	COG0295	Cytidine deaminase	134
644109184	231	53.51	1	228	3	230	9.0e-67	246	COG1346	Putative effector of murein hydrolase	230
644109185	135	45.45	8	128	4	124	6.0e-28	116	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
644109188	332	50.63	1	314	1	318	1.0e-123	436	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
644109189	345	58.72	4	328	11	335	5.0e-124	437	COG0502	Biotin synthase or related enzyme	335
644109190	385	43.15	1	381	1	387	6.0e-119	420	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
644109192	226	52.94	1	221	1	218	1.0e-70	259	COG0132	Dethiobiotin synthetase	223
644109193	670	71.49	1	670	1	663	0.0e+00	1117	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
644109196	302	41.75	3	302	1	309	2.0e-74	272	COG0391	Archaeal 2-phospho-L-lactate transferase/Bacterial gluconeogenesis factor, CofD/UPF0052 family	323
644109197	340	48.77	15	340	1	322	7.0e-108	383	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
644109198	172	44.64	5	170	2	168	2.0e-46	178	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
644109199	164	66.88	6	162	2	157	2.0e-60	225	COG0315	Molybdenum cofactor biosynthesis enzyme	157
644109200	81	47.62	1	81	1	84	1.0e-17	81.1	COG1977	Molybdopterin converting factor, small subunit	84
644109201	150	49.66	1	149	1	149	1.0e-48	185	COG0314	Molybdopterin synthase catalytic subunit	149
644109202	235	46.86	1	233	1	228	3.0e-38	151	COG0670	Integral membrane protein, interacts with FtsH	233
644109203	378	37.86	171	375	76	281	3.0e-23	103	COG0842	ABC-type multidrug transport system, permease component	286
644109204	391	29.63	93	389	4	282	8.0e-22	98.4	COG0842	ABC-type multidrug transport system, permease component	286
644109205	580	46.72	331	556	4	232	4.0e-68	252	COG1131	ABC-type multidrug transport system, ATPase component	293
644109206	342	27.78	1	332	11	346	1.0e-34	140	COG1566	Multidrug resistance efflux pump	352
644109207	701	18.26	26	701	49	768	1.0e-35	145	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644109208	339	30.19	20	322	15	315	7.0e-42	164	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
644109209	329	46.69	1	327	2	331	5.0e-53	201	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
644109210	343	40.23	1	342	4	343	1.0e-50	194	COG4779	ABC-type enterobactin transport system, permease component	346
644109211	283	49.42	17	273	2	258	5.0e-92	330	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
644109212	269	22.38	54	262	71	249	1.0e-13	70.8	COG4114	Ferric iron reductase protein FhuF, involved in iron transport	251
644109213	471	43.31	1	470	29	500	4.0e-119	421	COG0513	Superfamily II DNA and RNA helicase	513
644109216	409	37.96	7	409	5	413	5.0e-104	371	COG2195	Di- or tripeptidase	414
644109217	531	36.07	9	531	26	554	8.0e-97	348	COG0747	ABC-type transport system, periplasmic component	556
644109218	187	56.45	1	185	20	204	4.0e-74	270	COG1636	Predicted ATPase, Adenine nucleotide alpha hydrolases (AANH) superfamily	204
644109219	310	40.32	1	309	11	316	7.0e-80	290	COG0042	tRNA-dihydrouridine synthase	323
644109220	470	43.19	9	460	39	504	0.0e+00	488	COG0833	Amino acid permease	541
644109221	315	52.16	8	307	3	294	2.0e-88	319	COG2040	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)	300
644109224	180	32.96	8	180	1	177	4.0e-29	121	COG1437	Adenylate cyclase class IV, CYTH domain (includes archaeal enzymes of unknown function)	178
644109227	315	33.66	6	308	1	305	2.0e-61	229	COG1686	D-alanyl-D-alanine carboxypeptidase	389
644109228	768	36.88	48	456	1	390	2.0e-83	304	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
644109229	179	34.09	1	170	1	176	2.0e-35	141	COG1443	Isopentenyldiphosphate isomerase	185
644109231	215	32.68	14	215	3	206	6.0e-19	87.6	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644109232	281	26.89	160	277	4	122	1.0e-16	80.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644109234	699	31.41	13	699	2	642	7.0e-120	424	COG1199	Rad3-related DNA helicase	654
644109237	565	53.62	2	565	15	578	0.0e+00	669	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
644109238	432	19.28	4	364	9	287	4.0e-10	59.6	COG1566	Multidrug resistance efflux pump	352
644109239	455	26	18	438	41	455	5.0e-33	135	COG1538	Outer membrane protein TolC	457
644109247	475	42.41	153	472	81	391	2.0e-86	313	COG3497	Phage tail sheath protein FI	394
644109248	174	43.03	10	174	7	169	2.0e-50	192	COG3498	Phage tail tube protein FII	169
644109249	98	21.78	1	96	1	101	4.0e-06	43.1	COG0633	Ferredoxin	102
644109250	984	19.73	111	888	11	785	8.0e-22	99	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
644109255	336	49.51	12	318	4	265	8.0e-103	367	COG4608	ABC-type oligopeptide transport system, ATPase component	309
644109256	326	54.72	3	317	1	315	1.0e-122	433	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
644109257	300	52.56	9	300	1	288	1.0e-79	290	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644109258	339	48.97	1	339	1	317	4.0e-96	344	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644109259	535	36.36	1	535	2	553	7.0e-104	371	COG0747	ABC-type transport system, periplasmic component	556
644109260	447	44.18	27	444	15	435	5.0e-113	401	COG3493	Na+/citrate or Na+/malate symporter	438
644109264	240	46.72	2	230	1	224	5.0e-68	250	COG4565	Response regulator of citrate/malate metabolism	224
644109265	550	44.69	9	543	1	532	0.0e+00	537	COG3290	Sensor histidine kinase regulating citrate/malate metabolism	537
644109266	470	36.54	7	468	4	460	2.0e-54	207	COG0471	Di- and tricarboxylate transporter	461
644109267	552	56.26	1	551	1	544	0.0e+00	593	COG2985	Uncharacterized membrane protein YbjL, putative transporter	544
644109268	150	35.46	1	135	7	146	8.0e-26	109	COG0071	Molecular chaperone IbpA, HSP20 family	146
644109269	137	35.46	1	137	7	146	1.0e-28	118	COG0071	Molecular chaperone IbpA, HSP20 family	146
644109270	118	53.73	19	85	12	77	8.0e-17	79.2	COG5645	Uncharacterized conserved protein YceK	80
644109273	470	47.93	10	464	3	454	0.0e+00	550	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
644109274	440	39.49	8	429	4	427	1.0e-104	374	COG1455	Phosphotransferase system cellobiose-specific component IIC	432
644109275	87	53.66	1	82	21	102	5.0e-21	92.6	COG1440	Phosphotransferase system cellobiose-specific component IIB	102
644109277	340	33.02	26	340	4	326	2.0e-43	169	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
644109278	380	40.11	8	355	1	334	1.0e-55	210	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
644109279	264	46.69	1	257	2	258	2.0e-60	226	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
644109280	266	48.39	20	259	1	248	8.0e-78	283	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
644109282	429	23.19	11	421	25	433	5.0e-32	132	COG2271	Sugar phosphate permease	448
644109283	382	38.44	1	366	1	372	3.0e-81	295	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644109284	205	33.98	1	205	7	210	6.0e-49	187	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
644109285	298	41.64	1	296	2	302	2.0e-70	259	COG3734	2-keto-3-deoxy-galactonokinase	306
644109286	232	37.89	7	232	10	235	2.0e-47	182	COG2186	DNA-binding transcriptional regulator, FadR family	241
644109287	139	45.61	19	132	3	115	2.0e-28	118	COG4683	Uncharacterized protein	120
644109289	599	55.36	1	560	1	539	0.0e+00	717	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
644109290	302	46.76	9	301	1	285	6.0e-68	251	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644109291	325	45.82	1	322	1	317	7.0e-83	300	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644109292	323	43.63	3	313	2	311	6.0e-83	301	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
644109293	317	47.6	2	313	1	310	1.0e-91	330	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
644109294	294	39.58	1	286	2	288	1.0e-64	240	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
644109295	516	32.95	24	512	42	549	5.0e-81	295	COG0747	ABC-type transport system, periplasmic component	556
644109296	298	25.33	3	296	1	296	5.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
644109297	271	36.16	1	270	1	263	9.0e-54	203	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
644109299	480	46.84	5	477	3	454	0.0e+00	601	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
644109300	114	45	9	108	6	105	4.0e-22	96.4	COG1447	Phosphotransferase system cellobiose-specific component IIA	105
644109301	437	43.81	8	421	4	419	1.0e-105	376	COG1455	Phosphotransferase system cellobiose-specific component IIC	432
644109302	86	51.16	1	86	16	101	2.0e-20	90.7	COG1440	Phosphotransferase system cellobiose-specific component IIB	102
644109303	337	40.77	2	335	1	333	4.0e-85	308	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644109304	638	38.23	303	637	48	408	3.0e-53	203	COG0840	Methyl-accepting chemotaxis protein	408
644109305	122	35.59	6	121	4	117	2.0e-18	84.7	COG3791	Uncharacterized conserved protein	133
644109306	396	22.05	31	384	53	428	2.0e-16	80.6	COG2271	Sugar phosphate permease	448
644109307	805	63.8	1	556	2	555	0.0e+00	915	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
644109308	361	42.15	1	356	1	362	2.0e-108	386	COG1195	Recombinational DNA repair ATPase RecF	363
644109309	366	44.41	1	366	1	364	3.0e-106	378	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
644109310	465	56.58	6	461	1	408	0.0e+00	509	COG0593	Chromosomal replication initiation ATPase DnaA	408
644109312	119	49.56	6	117	1	113	2.0e-26	111	COG0594	RNase P protein component	117
644109313	85	62.86	9	78	7	76	2.0e-26	110	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
644109314	544	51.79	247	544	4	308	3.0e-80	293	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
644109315	454	54.47	1	454	1	454	0.0e+00	573	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
644109316	341	56.5	11	338	1	322	2.0e-116	412	COG3943	Uncharacterized conserved protein	329
644109317	181	28.4	12	91	4	84	3.0e-06	44.9	COG3077	Antitoxin component of the RelBE or YafQ-DinJ toxin-antitoxin module	88
644109318	284	35.38	1	269	2	275	1.0e-33	137	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
644109319	136	43	25	124	11	110	4.0e-26	110	COG1733	DNA-binding transcriptional regulator, HxlR family	120
644109320	183	22.64	1	159	6	164	2.0e-06	45.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644109322	219	65.09	7	217	5	216	8.0e-83	299	COG4380	Uncharacterized protein	216
644109323	119	49.12	6	119	9	121	2.0e-32	130	COG4259	Uncharacterized protein	121
644109324	223	50.42	1	223	1	238	1.0e-56	212	COG1462	Curli biogenesis system outer membrane secretion channel CsgG	252
644109325	626	45.06	200	626	2	429	0.0e+00	468	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
644109327	676	43.32	2	548	1	558	0.0e+00	691	COG0143	Methionyl-tRNA synthetase	558
644109328	369	42.86	47	323	1	265	4.0e-61	228	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
644109329	213	53.99	1	213	1	209	2.0e-74	272	COG0572	Uridine kinase	218
644109330	193	48.19	1	192	1	183	3.0e-54	204	COG0717	Deoxycytidine triphosphate deaminase	183
644109331	611	27.22	1	606	4	629	2.0e-74	273	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
644109332	450	68.23	1	444	1	446	0.0e+00	460	COG3069	C4-dicarboxylate transporter	451
644109333	528	51.87	1	237	8	248	1.0e-72	267	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
644109334	358	28.16	1	305	6	311	3.0e-35	142	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
644109335	378	46.56	40	286	1	239	2.0e-58	219	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
644109336	144	34.97	1	142	1	138	5.0e-32	129	COG0394	Protein-tyrosine-phosphatase	139
644109337	724	26.64	8	454	3	458	2.0e-58	220	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
644109338	291	60.07	1	288	1	285	1.0e-114	406	COG1209	dTDP-glucose pyrophosphorylase	286
644109341	370	41.11	2	368	1	370	1.0e-97	349	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
644109342	416	17.94	1	416	5	414	2.0e-09	57.4	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
644109346	332	21.26	11	260	5	254	7.0e-11	61.7	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
644109347	304	25.25	1	297	1	299	8.0e-32	131	COG1216	Glycosyltransferase, GT2 family	305
644109348	383	51.88	3	368	2	373	0.0e+00	467	COG0562	UDP-galactopyranose mutase	374
644109349	281	54.61	1	281	1	277	2.0e-93	335	COG1091	dTDP-4-dehydrorhamnose reductase	281
644109350	178	59.43	1	175	1	173	4.0e-60	224	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
644109351	289	56.75	1	289	1	286	2.0e-116	412	COG1209	dTDP-glucose pyrophosphorylase	286
644109352	298	51.34	1	298	2	290	3.0e-97	348	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
644109353	468	70.43	1	468	1	469	0.0e+00	807	COG0362	6-phosphogluconate dehydrogenase	473
644109358	185	33.77	32	107	24	100	2.0e-10	58.8	COG1605	Chorismate mutase	101
644109360	474	46.2	6	472	1	458	0.0e+00	524	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
644109362	255	38.64	81	255	6	181	1.0e-36	146	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644109364	367	23.72	60	302	1	250	3.0e-20	93.2	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
644109365	101	37.11	1	97	3	99	3.0e-20	89.6	COG1359	Quinol monooxygenase YgiN	100
644109366	285	35.84	8	282	3	271	1.0e-49	190	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
644109367	503	39.18	4	486	1	471	5.0e-124	438	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644109368	643	55.99	1	643	2	617	0.0e+00	895	COG3962	TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism	617
644109370	328	32.26	1	328	3	340	1.0e-52	200	COG0673	Predicted dehydrogenase	342
644109371	312	32.92	1	311	3	322	5.0e-44	171	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
644109372	515	48.92	1	506	4	498	0.0e+00	617	COG1129	ABC-type sugar transport system, ATPase component	500
644109373	343	50	22	342	5	315	1.0e-67	250	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
644109374	377	32	1	375	1	342	2.0e-55	209	COG0673	Predicted dehydrogenase	342
644109375	634	59.53	339	634	6	303	6.0e-122	432	COG3892	Myo-inositol catabolism protein IolC	310
644109376	296	31.88	5	292	1	274	1.0e-40	160	COG1082	Sugar phosphate isomerase/epimerase	274
644109377	278	60.37	1	269	1	269	3.0e-113	401	COG3718	5-deoxy-D-glucuronate isomerase	270
644109378	106	30.61	4	101	3	97	6.0e-10	55.8	COG3668	Plasmid stabilization system protein ParE	98
644109379	92	28.57	4	87	2	85	4.0e-08	49.7	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
644109381	565	34	19	557	9	532	4.0e-75	275	COG1178	ABC-type Fe3+ transport system, permease component	540
644109382	349	26.77	50	348	1	299	9.0e-43	167	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
644109384	487	41.94	6	485	3	456	0.0e+00	528	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
644109385	621	42.14	466	605	1	140	2.0e-42	167	COG2190	Phosphotransferase system IIA component	156
644109388	196	24.34	2	186	6	173	9.0e-20	90.4	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
644109389	293	31.03	1	285	6	291	1.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
644109390	212	40.57	1	211	1	211	7.0e-48	183	COG2910	Putative NADH-flavin reductase	211
644109391	554	35.42	11	551	1	531	2.0e-106	380	COG4615	ABC-type siderophore export system, fused ATPase and permease components	546
644109392	719	29.24	184	450	2	257	1.0e-33	138	COG3319	Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase	257
644109393	285	43.28	21	285	3	267	4.0e-81	294	COG0796	Glutamate racemase	269
644109394	625	54.78	2	625	1	608	0.0e+00	700	COG4206	Outer membrane cobalamin receptor protein	608
644109395	367	31.99	1	359	75	432	2.0e-85	309	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
644109397	209	23.08	1	193	3	196	1.0e-05	43.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644109398	468	38.73	7	460	3	454	0.0e+00	464	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
644109399	302	34.46	1	294	1	292	9.0e-44	170	COG0583	DNA-binding transcriptional regulator, LysR family	297
644109400	298	48.98	9	294	1	291	9.0e-86	310	COG0685	5,10-methylenetetrahydrofolate reductase	291
644109401	811	32.89	13	454	3	445	2.0e-101	363	COG0527	Aspartokinase	447
644109402	386	49.87	6	384	9	396	0.0e+00	471	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
644109403	105	93.33	1	105	1	105	9.0e-53	198	COG3060	Transcriptional regulator of met regulon	105
644109404	265	39.22	10	258	1	254	1.0e-60	226	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
644109405	320	27.76	1	320	4	318	2.0e-37	150	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
644109406	336	40.42	7	336	3	332	4.0e-45	175	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
644109407	59	46.67	1	59	7	65	4.0e-11	59.9	COG1724	Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family	66
644109408	136	52.54	1	59	2	59	2.0e-11	61.9	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
644109409	71	59.46	1	71	1	74	8.0e-21	91.9	COG0254	Ribosomal protein L31	75
644109410	732	50.61	1	731	1	729	0.0e+00	886	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
644109411	347	42.64	10	341	1	333	9.0e-96	343	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644109412	252	45.31	1	252	18	264	1.0e-42	167	COG3087	Cell division protein FtsN	264
644109413	176	73.71	1	175	4	178	1.0e-75	275	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
644109414	443	76.35	1	443	1	444	0.0e+00	730	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
644109415	305	46.67	7	305	5	300	9.0e-73	267	COG1575	1,4-dihydroxy-2-naphthoate octaprenyltransferase	303
644109416	161	44.17	4	161	12	174	8.0e-44	169	COG0684	Regulator of RNase E activity RraA	210
644109417	79	86.08	1	79	1	79	6.0e-13	65.9	COG3074	Cell division protein ZapB, interacts with FtsZ	79
644109418	279	51.56	7	259	2	241	1.0e-57	216	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
644109419	452	68.44	1	450	51	499	0.0e+00	751	COG0554	Glycerol kinase	499
644109420	339	70.73	1	328	1	327	0.0e+00	488	COG1494	Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase or related protein	332
644109421	248	31.34	1	248	2	266	7.0e-47	180	COG1018	Ferredoxin-NADP reductase	266
644109422	140	31.47	1	138	5	124	2.0e-16	78.4	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
644109424	255	58.27	1	253	1	251	4.0e-84	304	COG0149	Triosephosphate isomerase	251
644109425	367	50.41	6	366	4	346	8.0e-128	450	COG2957	Agmatine/peptidylarginine deiminase	346
644109426	294	33.8	2	283	1	268	8.0e-55	207	COG0388	Predicted amidohydrolase	274
644109427	252	51.22	1	246	2	243	5.0e-80	290	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
644109428	531	41.22	287	531	13	256	2.0e-44	174	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
644109429	133	36.57	1	133	1	134	9.0e-28	115	COG0848	Biopolymer transport protein ExbD	137
644109430	238	40.5	14	209	11	210	1.0e-36	146	COG0811	Biopolymer transport protein ExbB/TolQ	216
644109431	292	27.57	49	291	5	244	6.0e-14	71.7	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
644109432	320	28.97	8	319	13	328	4.0e-31	128	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
644109433	761	18.25	22	759	15	768	1.0e-28	122	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644109436	309	22.11	3	294	1	289	6.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
644109437	320	55.72	1	320	1	341	1.0e-116	413	COG0205	6-phosphofructokinase	347
644109438	300	39.19	1	295	3	298	4.0e-72	265	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
644109439	395	40.05	1	390	3	394	5.0e-66	245	COG2814	Predicted arabinose efflux permease, MFS family	394
644109440	174	34.69	5	150	7	153	4.0e-15	74.6	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
644109441	232	44.83	3	232	2	229	2.0e-60	225	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644109442	456	33.54	140	455	17	331	3.0e-40	159	COG0642	Signal transduction histidine kinase	336
644109445	196	43.41	2	194	1	205	4.0e-47	181	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644109446	501	61.94	5	495	1	493	0.0e+00	581	COG3851	Signal transduction histidine kinase, glucose-6-phosphate specific	497
644109447	446	51.45	1	445	1	448	0.0e+00	519	COG2271	Sugar phosphate permease	448
644109448	457	45.08	4	457	3	447	4.0e-125	441	COG2271	Sugar phosphate permease	448
644109449	154	55.19	1	153	2	154	2.0e-59	221	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
644109451	318	31.94	7	315	1	308	4.0e-36	145	COG0679	Predicted permease	311
644109452	249	35.43	7	248	5	256	3.0e-45	175	COG0584	Glycerophosphoryl diester phosphodiesterase	257
644109453	357	53.28	1	351	1	338	3.0e-127	448	COG3839	ABC-type sugar transport system, ATPase component	338
644109454	281	41.67	5	277	7	276	5.0e-56	211	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
644109455	295	40.34	4	291	2	290	8.0e-58	217	COG1175	ABC-type sugar transport system, permease component	295
644109456	444	27.21	6	439	5	433	2.0e-50	193	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
644109458	119	45.74	26	119	2	93	2.0e-22	97.7	COG4453	Uncharacterized conserved protein, DUF1778 family	95
644109461	141	37.3	1	126	1	122	2.0e-25	108	COG4737	Uncharacterized protein	123
644109462	99	33.67	1	98	15	104	2.0e-13	67.3	COG2944	DNA-binding transcriptional regulator YiaG, XRE-type HTH domain	104
644109463	252	45.06	1	252	1	252	3.0e-68	252	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
644109465	173	46.01	7	166	3	161	2.0e-40	158	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
644109466	192	43.23	1	189	4	192	2.0e-47	182	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
644109467	89	77.27	1	88	1	88	4.0e-37	146	COG3084	Uncharacterized protein YihD, DUF1040 family	88
644109468	328	33.33	1	325	1	331	7.0e-68	251	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
644109470	929	60.73	330	929	2	593	0.0e+00	822	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
644109471	203	56.92	1	194	6	200	5.0e-71	260	COG0218	GTP-binding protein EngB required for normal cell division	200
644109473	184	53.29	13	175	14	169	5.0e-29	120	COG3078	Ribosome assembly protein YihI, activator of Der GTPase	169
644109476	457	42.43	14	447	1	416	1.0e-123	436	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
644109479	470	52.23	1	470	2	457	0.0e+00	566	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644109480	349	62.92	1	349	1	356	0.0e+00	471	COG3852	Signal transduction histidine kinase, nitrogen specific	363
644109482	469	50.63	1	469	1	443	0.0e+00	529	COG0174	Glutamine synthetase	443
644109483	607	72.59	1	602	1	601	0.0e+00	1046	COG1217	Predicted membrane GTPase involved in stress response	603
644109484	203	21.21	1	187	5	201	4.0e-19	88	COG1011	FMN phosphatase YigB, HAD superfamily	229
644109485	145	58.62	1	145	1	145	2.0e-60	224	COG1490	D-Tyr-tRNAtyr deacylase	145
644109486	313	33.62	35	145	39	152	5.0e-08	52.2	COG2153	Predicted N-acyltransferase, GNAT family	155
644109488	462	42.63	18	462	2	438	7.0e-104	371	COG2233	Xanthine/uracil permease	451
644109489	693	57.16	1	686	1	677	0.0e+00	908	COG1200	RecG-like helicase	677
644109491	699	46.1	1	697	6	701	0.0e+00	921	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
644109492	91	50	1	73	1	74	8.0e-13	65.3	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
644109493	207	58.42	1	190	1	187	2.0e-77	281	COG0194	Guanylate kinase	191
644109494	563	28.08	29	562	1	581	2.0e-121	430	COG0272	NAD-dependent DNA ligase	667
644109495	559	28.95	1	558	4	548	3.0e-122	432	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
644109497	174	29.65	1	174	1	199	7.0e-19	87	COG3637	Opacity protein and related surface antigens	199
644109498	535	28.22	3	514	2	514	2.0e-73	270	COG4943	Environmental sensor c-di-GMP phosphodiesterase, contains periplasmic CSS-motif sensor and cytoplasmic EAL domain	524
644109499	399	54.7	1	395	1	403	0.0e+00	563	COG2081	Predicted flavoprotein YhiN	408
644109502	145	23.03	1	141	3	154	1.0e-11	62.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
644109503	447	45.79	21	447	1	411	0.0e+00	519	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
644109504	437	23.44	30	400	1	372	1.0e-34	141	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644109505	631	31.83	1	488	1	497	8.0e-75	275	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
644109507	680	61.82	1	680	8	683	0.0e+00	992	COG0339	Zn-dependent oligopeptidase	683
644109508	849	19.56	103	849	22	768	1.0e-40	162	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644109509	170	31.14	1	164	5	171	2.0e-22	98.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644109510	329	35.96	17	329	11	322	3.0e-59	222	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
644109511	273	24.1	21	269	8	244	2.0e-14	73.3	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
644109513	563	34.66	6	560	3	571	3.0e-109	389	COG0443	Molecular chaperone DnaK (HSP70)	579
644109514	905	19.83	789	898	5	124	1.0e-05	46	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
644109516	280	66.31	2	280	1	279	4.0e-122	430	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
644109517	450	39.74	1	450	1	454	5.0e-130	458	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
644109518	95	39.33	1	88	1	89	1.0e-13	68.4	COG2026	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system	90
644109520	260	31.91	3	259	48	259	7.0e-35	140	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
644109521	251	27.95	1	251	4	241	6.0e-25	107	COG1651	Protein-disulfide isomerase	244
644109522	234	26.49	7	190	14	191	8.0e-19	87.4	COG4282	Cell wall assembly regulator SMI1	191
644109523	207	33.66	5	207	4	208	1.0e-28	119	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644109524	290	26.53	6	290	2	291	2.0e-24	106	COG0583	DNA-binding transcriptional regulator, LysR family	297
644109525	169	58.75	8	166	6	165	2.0e-62	231	COG3479	Phenolic acid decarboxylase	175
644109526	345	24.73	156	340	1	174	1.0e-15	77.5	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
644109527	344	26.84	13	325	6	334	1.0e-29	124	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
644109528	557	52.62	14	539	4	535	0.0e+00	615	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
644109529	286	43.32	9	283	4	280	8.0e-59	220	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644109530	314	40.38	1	307	1	314	2.0e-64	239	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644109531	545	25.45	11	545	14	554	2.0e-61	230	COG0747	ABC-type transport system, periplasmic component	556
644109534	380	24.76	73	277	16	219	2.0e-24	106	COG1647	Esterase/lipase	243
644109535	244	35.65	1	223	9	235	7.0e-48	184	COG2186	DNA-binding transcriptional regulator, FadR family	241
644109536	398	57.87	1	394	1	362	0.0e+00	524	COG1312	D-mannonate dehydratase	362
644109538	402	28.87	51	399	98	478	5.0e-35	142	COG5434	Polygalacturonase	542
644109539	389	22.46	10	321	10	289	6.0e-15	75.4	COG1566	Multidrug resistance efflux pump	352
644109540	712	34.86	3	698	7	695	0.0e+00	561	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
644109541	468	24.16	25	451	1	447	2.0e-39	156	COG1538	Outer membrane protein TolC	457
644109543	548	64.4	1	545	1	544	0.0e+00	674	COG4615	ABC-type siderophore export system, fused ATPase and permease components	546
644109544	346	43.66	15	343	11	346	1.0e-83	303	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
644109545	173	37.79	1	171	1	169	5.0e-47	180	COG0703	Shikimate kinase	172
644109546	94	73.4	1	94	1	94	3.0e-37	146	COG3123	Uncharacterized conserved protein YaiE, UPF0345 family	94
644109548	333	44.65	4	321	6	309	2.0e-83	302	COG1397	ADP-ribosylglycohydrolase	314
644109549	325	31.83	18	318	1	307	2.0e-36	146	COG0524	Sugar or nucleoside kinase, ribokinase family	311
644109550	248	37.5	20	247	4	235	5.0e-52	197	COG2188	DNA-binding transcriptional regulator, GntR family	236
644109551	596	33.25	213	596	2	408	9.0e-47	182	COG0840	Methyl-accepting chemotaxis protein	408
644109552	309	69.81	2	309	1	302	7.0e-126	443	COG2974	DNA recombination-dependent growth factor C	303
644109553	303	34.95	1	299	7	305	1.0e-56	213	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
644109554	1227	21.78	1	744	1	756	2.0e-37	152	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
644109555	412	25.85	1	406	1	388	3.0e-55	209	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
644109556	229	47.16	3	227	1	227	1.0e-63	236	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644109557	440	32.05	98	422	111	447	3.0e-47	182	COG5002	Signal transduction histidine kinase	459
644109558	312	32.28	1	301	14	318	6.0e-50	191	COG0226	ABC-type phosphate transport system, periplasmic component	318
644109559	368	22.38	4	365	1	329	8.0e-57	214	COG0620	Methionine synthase II (cobalamin-independent)	330
644109560	439	53.13	4	432	1	431	2.0e-127	449	COG1114	Branched-chain amino acid permeases	431
644109561	424	20.07	110	407	51	316	7.0e-22	98.8	COG0668	Small-conductance mechanosensitive channel	316
644109562	200	57.14	1	196	2	194	1.0e-74	272	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
644109563	193	61.14	1	193	1	193	1.0e-70	258	COG3124	Acyl carrier protein phosphodiesterase	193
644109564	355	58.92	1	349	1	348	0.0e+00	520	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
644109565	348	21.55	118	322	69	291	3.0e-09	56.4	COG4974	Site-specific recombinase XerD	300
644109586	237	26.09	25	229	7	194	2.0e-26	112	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
644109591	458	36.07	3	427	5	427	7.0e-76	278	COG0305	Replicative DNA helicase	435
644109605	159	45.7	12	159	2	152	1.0e-31	129	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
644109631	381	64.86	3	372	1	369	0.0e+00	584	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
644109632	110	43.88	13	110	1	97	5.0e-25	106	COG1862	Preprotein translocase subunit YajC	97
644109633	604	51.74	64	604	1	506	0.0e+00	482	COG0342	Preprotein translocase subunit SecD	506
644109634	324	51.96	10	315	1	304	4.0e-89	321	COG0341	Preprotein translocase subunit SecF	305
644109636	149	59.73	1	149	1	149	1.0e-56	212	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
644109637	378	76.06	12	153	5	146	5.0e-64	238	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
644109638	158	59.62	1	156	1	152	2.0e-51	195	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
644109639	139	51.72	2	139	6	150	1.0e-36	145	COG0781	Transcription termination factor NusB	151
644109640	326	52.8	4	322	4	317	5.0e-101	361	COG0611	Thiamine monophosphate kinase	317
644109641	178	46.88	16	172	3	160	5.0e-40	157	COG1267	Phosphatidylglycerophosphatase A	160
644109642	621	63.93	8	620	2	622	0.0e+00	983	COG1154	Deoxyxylulose-5-phosphate synthase	627
644109643	303	37.57	3	303	2	322	4.0e-65	241	COG0142	Geranylgeranyl pyrophosphate synthase	322
644109644	82	49.37	2	80	3	81	2.0e-13	67.3	COG1722	Exonuclease VII small subunit	81
644109646	482	41.45	1	384	2	383	2.0e-114	406	COG0301	Adenylyl- and sulfurtransferase ThiI, participates in tRNA 4-thiouridine and thiamine biosynthesis	383
644109647	196	30.16	1	178	1	188	3.0e-21	95.2	COG0693	Putative intracellular protease/amidase	188
644109648	302	36.88	1	288	1	300	9.0e-62	230	COG1893	Ketopantoate reductase	307
644109649	163	69.94	1	163	4	165	3.0e-62	230	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
644109650	454	22.65	29	387	30	384	6.0e-22	99.1	COG2814	Predicted arabinose efflux permease, MFS family	394
644109651	296	44.79	1	288	17	302	5.0e-81	294	COG0109	Polyprenyltransferase (heme O synthase)	304
644109652	110	63.55	2	108	3	109	3.0e-24	103	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
644109653	204	48.51	4	204	10	209	2.0e-51	195	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
644109654	663	54.36	38	608	1	566	0.0e+00	628	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
644109655	320	47.66	12	267	2	247	1.0e-71	263	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
644109656	495	22.71	89	403	83	386	2.0e-09	57.5	COG2814	Predicted arabinose efflux permease, MFS family	394
644109657	192	63.54	1	192	14	204	3.0e-62	231	COG3056	Uncharacterized lipoprotein YajG	204
644109658	104	56.47	1	84	3	87	2.0e-25	107	COG0271	Stress-induced morphogen (activity unknown)	90
644109659	434	49.55	1	430	1	439	5.0e-115	408	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
644109660	207	74.61	14	206	1	193	2.0e-89	321	COG0740	ATP-dependent protease ClpP, protease subunit	200
644109661	424	74.75	16	419	1	403	0.0e+00	715	COG1219	ATP-dependent protease Clp, ATPase subunit	408
644109662	793	71.45	2	779	1	781	0.0e+00	1253	COG0466	ATP-dependent Lon protease, bacterial type	782
644109663	90	62.22	1	90	2	91	4.0e-29	119	COG0776	Bacterial nucleoid DNA-binding protein	94
644109664	626	22.22	153	409	53	320	9.0e-06	45.9	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
644109665	121	29.73	11	121	40	149	8.0e-13	65.9	COG1555	DNA uptake protein ComE and related DNA-binding proteins	149
644109666	132	38.76	5	132	10	136	7.0e-26	109	COG0824	Acyl-CoA thioesterase FadM	137
644109667	231	51.87	1	213	2	211	1.0e-78	286	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
644109668	342	29.3	13	322	2	300	3.0e-80	292	COG0031	Cysteine synthase	300
644109670	153	41.72	1	151	5	154	6.0e-36	143	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644109671	589	37.46	1	574	1	567	2.0e-127	450	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
644109672	592	39.09	8	578	1	567	3.0e-120	426	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
644109674	112	66.96	1	112	1	112	2.0e-38	150	COG0347	Nitrogen regulatory protein PII	112
644109675	428	55.31	27	427	1	403	1.0e-118	419	COG0004	Ammonia channel protein AmtB	409
644109676	287	62.19	1	283	1	283	3.0e-107	381	COG1946	Acyl-CoA thioesterase	289
644109677	193	46.34	1	164	1	158	1.0e-29	122	COG3126	Uncharacterized lipoprotein YbaY	158
644109678	106	58.42	4	104	3	103	5.0e-33	132	COG3695	Alkylated DNA nucleotide flippase Atl1, participates in nucleotide excision repair, Ada-like DNA-binding domain	103
644109681	82	39.76	1	82	1	72	9.0e-17	78.4	COG0254	Ribosomal protein L31	75
644109685	451	21.72	192	437	41	302	4.0e-08	52.8	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644109688	302	51.19	3	297	2	289	1.0e-57	216	COG5464	Predicted transposase YdaD	289
644109689	552	58.54	30	544	1	529	0.0e+00	562	COG4147	Na+(or H+)/acetate symporter ActP	529
644109690	103	66.02	1	103	1	102	2.0e-32	130	COG3162	Uncharacterized membrane protein, DUF485 family	102
644109691	653	45.66	68	631	1	528	0.0e+00	677	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
644109694	789	26.19	99	788	35	718	5.0e-71	262	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
644109695	174	27.74	17	168	17	171	1.0e-23	102	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644109696	315	31.31	12	314	12	321	4.0e-42	165	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
644109697	336	21.41	2	332	6	339	3.0e-09	56.1	COG0628	Predicted PurR-regulated permease PerM	355
644109698	508	28.51	3	465	7	460	6.0e-87	315	COG2211	Na+/melibiose symporter or related transporter	467
644109700	495	48.54	14	490	1	473	0.0e+00	536	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
644109701	426	63.12	1	423	6	426	0.0e+00	624	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
644109702	357	37.5	1	235	2	232	8.0e-38	151	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
644109703	265	35.74	1	255	3	263	7.0e-48	184	COG0388	Predicted amidohydrolase	274
644109704	178	42.13	1	177	4	181	7.0e-37	146	COG3038	Cytochrome b561	181
644109705	1177	40.16	1	379	3	357	2.0e-97	351	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
644109707	308	21.96	8	303	1	292	2.0e-24	107	COG0583	DNA-binding transcriptional regulator, LysR family	297
644109708	165	20.37	1	159	5	166	3.0e-06	45	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
644109709	208	35.89	1	208	1	208	6.0e-27	114	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644109710	260	25.56	1	253	3	265	7.0e-30	124	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644109714	194	31.49	1	179	1	174	8.0e-32	130	COG2184	Fido, protein-threonine AMPylation domain	201
644109715	94	39.33	1	88	1	89	9.0e-14	68.4	COG2026	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system	90
644109718	88	29.76	1	84	7	90	1.0e-07	48.4	COG4453	Uncharacterized conserved protein, DUF1778 family	95
644109719	73	35.38	5	68	26	90	5.0e-07	46	COG2026	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system	90
644109722	775	26.78	336	775	44	512	4.0e-85	309	COG3378	Phage- or plasmid-associated DNA primase	517
644109726	61	57.14	1	56	14	69	2.0e-13	67.6	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
644109731	398	22.9	97	395	6	309	1.0e-11	64.6	COG0582	Integrase	309
644109732	160	62.75	8	160	2	153	4.0e-58	217	COG0691	tmRNA-binding protein	153
644109733	148	56.85	1	145	1	146	2.0e-54	204	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
644109734	93	69.57	1	92	4	95	5.0e-28	115	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
644109736	111	44.44	1	111	4	120	5.0e-30	122	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
644109737	553	50.63	1	553	1	554	0.0e+00	619	COG0497	DNA repair ATPase RecN	557
644109738	292	47.2	6	289	1	281	3.0e-81	295	COG0061	NAD kinase	281
644109739	195	46.43	1	193	1	192	3.0e-43	168	COG0576	Molecular chaperone GrpE (heat shock protein)	193
644109740	391	46.98	1	391	20	415	2.0e-83	302	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
644109741	67	42.42	1	66	1	66	3.0e-16	76.5	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
644109742	388	19.21	16	386	13	388	6.0e-08	52.5	COG2814	Predicted arabinose efflux permease, MFS family	394
644109743	365	37.4	5	361	4	358	1.0e-86	313	COG0371	Glycerol dehydrogenase or related enzyme, iron-containing ADH family	360
644109745	421	22.02	1	421	5	432	3.0e-30	126	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
644109746	292	40.27	3	292	1	290	2.0e-55	209	COG1175	ABC-type sugar transport system, permease component	295
644109747	270	35.38	2	270	5	281	1.0e-43	169	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
644109748	361	52.81	1	356	1	338	1.0e-123	436	COG3839	ABC-type sugar transport system, ATPase component	338
644109749	507	42.57	20	340	27	357	7.0e-80	291	COG3867	Arabinogalactan endo-1,4-beta-galactosidase	403
644109750	345	27.56	2	337	1	328	3.0e-49	189	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644109752	475	44.16	7	467	2	454	0.0e+00	502	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
644109753	639	29.52	100	456	2	376	4.0e-58	219	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
644109753	639	48.67	489	637	4	153	5.0e-45	176	COG2190	Phosphotransferase system IIA component	156
644109756	258	44.94	14	257	13	259	7.0e-63	234	COG3455	Type VI protein secretion system component VasF	262
644109757	445	53.59	1	444	1	446	0.0e+00	521	COG3522	Predicted component of the type VI protein secretion system	446
644109758	173	32.16	2	171	5	159	3.0e-31	127	COG3521	Predicted component of the type VI protein secretion system	159
644109759	406	34.5	7	403	3	428	9.0e-65	241	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
644109760	332	43.95	16	328	17	328	1.0e-82	299	COG3520	Predicted component of the type VI protein secretion system	335
644109761	588	38.41	1	585	3	618	0.0e+00	511	COG3519	Type VI protein secretion system component VasA	621
644109762	143	32.19	7	141	7	152	1.0e-19	88.9	COG3518	Predicted component of the type VI protein secretion system	157
644109763	492	54.25	1	492	4	493	0.0e+00	729	COG3517	Predicted component of the type VI protein secretion system	495
644109764	167	44.72	9	167	9	168	8.0e-43	166	COG3516	Predicted component of the type VI protein secretion system	169
644109774	417	60.67	1	417	4	417	0.0e+00	594	COG0014	Gamma-glutamyl phosphate reductase	417
644109775	367	56.79	1	366	3	368	0.0e+00	467	COG0263	Glutamate 5-kinase	369
644109777	699	25.43	465	632	65	235	1.0e-05	45.3	COG0666	Ankyrin repeat	235
644109779	111	25.62	1	110	1	119	6.0e-12	62.6	COG3232	5-carboxymethyl-2-hydroxymuconate isomerase	127
644109781	152	18.67	1	144	14	179	3.0e-24	104	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
644109782	486	35.77	6	483	1	412	1.0e-104	373	COG2195	Di- or tripeptidase	414
644109783	352	43.66	2	347	1	352	2.0e-91	329	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
644109786	244	45.76	1	233	5	240	1.0e-64	239	COG3034	Murein L,D-transpeptidase YafK	298
644109787	255	49.41	1	255	1	248	9.0e-86	309	COG0121	Predicted glutamine amidotransferase	252
644109788	193	58.1	2	179	1	176	2.0e-66	245	COG0279	Phosphoheptose isomerase	176
644109789	815	27.48	119	507	11	382	1.0e-44	175	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644109791	400	43.01	32	397	36	407	6.0e-101	361	COG4857	5-Methylthioribose kinase, methionine salvage pathway	408
644109792	344	49.7	13	331	11	336	2.0e-103	369	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
644109793	181	47.22	1	179	1	174	3.0e-50	191	COG1791	Acireductone dioxygenase (methionine salvage), cupin superfamily	181
644109794	229	47.64	1	212	3	213	4.0e-66	244	COG4229	Enolase-phosphatase E1 involved in merthionine salvage	229
644109795	205	30.73	1	201	3	194	2.0e-31	128	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
644109796	385	36.56	21	385	20	388	3.0e-88	318	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
644109797	255	33.33	2	255	1	267	8.0e-47	180	COG0388	Predicted amidohydrolase	274
644109798	420	23.82	15	413	2	403	2.0e-34	140	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644109799	414	36.75	11	409	3	383	3.0e-103	368	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
644109800	247	58.09	2	242	1	240	1.0e-103	369	COG1126	ABC-type polar amino acid transport system, ATPase component	240
644109801	218	40.74	2	216	7	222	4.0e-51	194	COG0765	ABC-type amino acid transport system, permease component	222
644109802	221	46.79	3	216	1	218	2.0e-48	186	COG0765	ABC-type amino acid transport system, permease component	222
644109803	268	28.41	9	268	3	273	6.0e-30	124	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644109804	279	27.76	1	275	2	281	2.0e-46	179	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
644109805	528	37.62	10	527	17	538	8.0e-120	424	COG0405	Gamma-glutamyltranspeptidase	539
644109807	472	37.23	7	460	2	467	1.0e-100	360	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
644109809	130	15.6	1	125	2	137	1.0e-06	46	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644109810	400	66.92	1	396	1	386	0.0e+00	528	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
644109811	417	60	119	403	6	290	3.0e-106	378	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
644109812	334	29.73	1	332	3	300	8.0e-56	210	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
644109813	386	31.13	36	383	3	345	3.0e-63	236	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
644109814	406	24.81	9	402	3	393	6.0e-23	102	COG2814	Predicted arabinose efflux permease, MFS family	394
644109815	243	43.7	5	241	2	234	4.0e-37	148	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
644109817	133	36.08	34	130	11	105	3.0e-08	50.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
644109818	391	43.75	17	351	8	343	2.0e-91	329	COG1566	Multidrug resistance efflux pump	352
644109820	394	43.78	3	394	2	403	1.0e-102	366	COG1972	Nucleoside permease NupC	404
644109822	383	38.06	139	383	15	259	2.0e-62	233	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
644109824	237	64	1	225	1	224	3.0e-78	284	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
644109825	803	45	3	625	1	598	0.0e+00	560	COG1042	Acyl-CoA synthetase (NDP forming)	598
644109826	488	47.79	13	484	4	471	0.0e+00	536	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
644109827	340	31.96	2	339	1	340	1.0e-79	290	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
644109828	342	33.33	16	314	1	298	2.0e-64	239	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
644109829	159	22.52	1	150	9	159	1.0e-11	62.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
644109830	427	40.69	50	425	5	378	5.0e-78	285	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
644109831	228	33.49	1	211	5	215	8.0e-38	150	COG1802	DNA-binding transcriptional regulator, GntR family	230
644109832	453	20.53	8	405	31	389	5.0e-15	75.8	COG4222	Uncharacterized conserved protein	391
644109834	446	20.84	73	429	76	429	4.0e-21	96.5	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
644109835	227	24	9	181	21	194	5.0e-19	88.1	COG0811	Biopolymer transport protein ExbB/TolQ	216
644109836	746	19.92	48	746	68	768	4.0e-33	136	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644109837	246	28.72	41	232	41	233	6.0e-07	48.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
644109838	134	26.87	1	133	3	134	1.0e-18	85.7	COG0848	Biopolymer transport protein ExbD	137
644109839	397	23.63	49	394	51	390	4.0e-20	92.6	COG2814	Predicted arabinose efflux permease, MFS family	394
644109841	438	27	12	420	14	423	1.0e-34	141	COG1457	Purine-cytosine permease or related protein	442
644109843	297	34.56	1	293	1	295	4.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
644109844	308	31.83	1	308	1	311	3.0e-33	135	COG0679	Predicted permease	311
644109845	754	44.61	26	754	21	719	0.0e+00	696	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
644109846	449	25.12	5	418	1	371	8.0e-49	188	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644109847	448	19.41	43	429	45	432	3.0e-14	73.7	COG2271	Sugar phosphate permease	448
644109848	249	53.72	5	245	2	233	2.0e-78	285	COG3910	Predicted ATPase	233
644109850	189	32.42	17	188	6	183	3.0e-17	81.7	COG3539	Pilin (type 1 fimbria component protein)	184
644109853	249	36.44	8	238	10	235	6.0e-44	170	COG3121	P pilus assembly protein, chaperone PapD	235
644109854	832	33.85	21	832	18	835	0.0e+00	603	COG3188	Outer membrane usher protein FimD/PapC	835
644109855	182	29.79	1	182	1	184	5.0e-16	77.9	COG3539	Pilin (type 1 fimbria component protein)	184
644109856	261	31.19	1	106	1	107	1.0e-08	53.4	COG3710	DNA-binding winged helix-turn-helix (wHTH) domain	148
644109858	190	24.08	1	190	6	193	6.0e-11	60.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644109861	133	24.29	8	130	2	138	2.0e-09	54.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644109862	184	25.3	3	168	13	177	4.0e-09	54.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644109863	205	21.83	1	194	3	195	3.0e-07	48.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644109864	195	30.6	1	181	1	172	3.0e-30	124	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
644109866	395	40.36	14	395	8	391	1.0e-61	230	COG2814	Predicted arabinose efflux permease, MFS family	394
644109867	318	36.79	208	313	18	123	1.0e-20	94.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644109872	75	30.43	3	71	11	79	4.0e-09	53.2	COG5302	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid	80
644109875	80	75.38	3	67	5	69	7.0e-23	98.6	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
644109878	717	46.38	97	716	1	557	0.0e+00	680	COG1982	Arginine/lysine/ornithine decarboxylase	557
644109879	483	48.71	13	478	1	462	0.0e+00	513	COG1113	L-asparagine transporter and related permeases	462
644109880	246	29.46	1	234	3	237	4.0e-22	98.4	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
644109882	407	62.59	8	407	5	399	0.0e+00	539	COG5441	Uncharacterized protein, UPF0261 family	401
644109883	277	73.8	7	277	6	276	2.0e-118	418	COG5564	Predicted TIM-barrel enzyme	276
644109884	328	26.53	8	328	38	357	3.0e-36	145	COG4188	Predicted dienelactone hydrolase	365
644109885	363	31.97	225	346	4	122	2.0e-14	74.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644109886	357	22.33	46	353	1	296	2.0e-38	153	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
644109887	90	76.4	1	89	1	89	1.0e-39	154	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
644109888	368	52.14	1	350	5	340	4.0e-122	431	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
644109889	239	50.88	17	239	1	226	4.0e-77	281	COG0220	tRNA G46 methylase TrmB	227
644109890	114	64.86	1	111	9	119	1.0e-38	151	COG3171	Uncharacterized conserved protein YggL, DUF469 family	119
644109892	353	39.89	1	353	1	316	1.0e-84	306	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
644109894	238	47.93	1	236	7	248	5.0e-54	204	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
644109895	231	74.89	1	227	1	227	6.0e-103	367	COG3066	DNA mismatch repair protein MutH	229
644109896	177	22.93	2	152	4	151	4.0e-11	61.5	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
644109897	721	58.3	1	721	1	729	0.0e+00	932	COG3605	Signal transduction protein containing GAF and PtsI domains	756
644109899	160	50.94	1	158	1	158	2.0e-40	158	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
644109900	97	63.92	1	97	1	96	9.0e-29	118	COG0234	Co-chaperonin GroES (HSP10)	96
644109901	548	49.45	1	534	1	524	0.0e+00	496	COG0459	Chaperonin GroEL (HSP60 family)	524
644109902	205	35.09	44	202	1	171	1.0e-30	126	COG3161	4-hydroxybenzoate synthetase (chorismate-pyruvate lyase)	174
644109903	287	42.71	1	287	1	288	2.0e-55	209	COG0382	4-hydroxybenzoate polyprenyltransferase	289
644109904	825	67.28	1	808	1	808	0.0e+00	1105	COG2937	Glycerol-3-phosphate O-acyltransferase	810
644109905	121	54.17	1	120	2	121	1.0e-32	131	COG0818	Diacylglycerol kinase	123
644109906	202	51.24	1	198	1	199	5.0e-58	217	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
644109907	69	42.86	1	63	3	65	8.0e-10	55.3	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
644109908	169	31.97	6	152	1	145	3.0e-32	131	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
644109909	232	34.01	1	230	1	242	5.0e-40	158	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
644109910	298	24.32	7	298	1	294	2.0e-25	109	COG0583	DNA-binding transcriptional regulator, LysR family	297
644109911	331	68	1	325	1	322	0.0e+00	520	COG0435	Glutathionyl-hydroquinone reductase	324
644109912	131	42.75	4	131	11	141	1.0e-15	75.4	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
644109914	131	68.29	7	129	8	130	5.0e-34	136	COG5393	Uncharacterized membrane protein YqjE	131
644109915	101	56.12	4	101	7	104	1.0e-25	108	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
644109918	227	35.38	26	219	14	208	4.0e-33	135	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
644109919	258	33.19	1	232	3	238	4.0e-47	181	COG2186	DNA-binding transcriptional regulator, FadR family	241
644109920	433	22.95	5	416	24	438	2.0e-29	123	COG2271	Sugar phosphate permease	448
644109921	469	60.22	3	467	1	463	0.0e+00	687	COG1904	Glucuronate isomerase	463
644109922	488	32.05	1	487	1	473	2.0e-115	410	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
644109923	496	53.54	103	496	1	381	0.0e+00	525	COG2721	Altronate dehydratase	381
644109925	407	79.5	1	400	8	407	0.0e+00	565	COG3633	Na+/serine symporter	407
644109926	317	33.6	76	317	17	250	8.0e-42	164	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
644109927	332	28.48	1	293	3	308	5.0e-44	171	COG0673	Predicted dehydrogenase	342
644109928	379	36.51	72	375	2	300	2.0e-83	303	COG2813	16S rRNA G1207 methylase RsmC	300
644109929	691	44.6	4	356	3	362	7.0e-109	388	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
644109931	162	35.44	1	158	2	157	1.0e-20	92.7	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
644109934	640	29.38	104	452	10	380	2.0e-57	217	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
644109934	640	44.81	486	638	1	154	3.0e-45	177	COG2190	Phosphotransferase system IIA component	156
644109935	576	24.76	31	476	1	473	1.0e-41	164	COG3119	Arylsulfatase A or related enzyme	475
644109936	487	27.05	30	475	4	461	3.0e-51	196	COG3119	Arylsulfatase A or related enzyme	475
644109937	407	47.5	2	400	1	377	1.0e-109	390	COG0641	Sulfatase maturation enzyme AslB, radical SAM superfamily	378
644109938	564	30.53	43	462	3	443	5.0e-55	209	COG3119	Arylsulfatase A or related enzyme	475
644109939	462	45.4	1	461	1	456	0.0e+00	558	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
644109941	254	32.06	51	253	12	185	3.0e-23	102	COG0693	Putative intracellular protease/amidase	188
644109942	300	25.84	6	299	2	292	3.0e-32	132	COG0583	DNA-binding transcriptional regulator, LysR family	297
644109945	167	32.14	1	167	1	168	1.0e-36	145	COG3663	G:T/U-mismatch repair DNA glycosylase	169
644109946	611	50.42	254	610	1	342	1.0e-99	357	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
644109947	584	43.73	4	573	1	556	0.0e+00	512	COG0358	DNA primase (bacterial type)	568
644109948	71	61.19	1	67	1	67	2.0e-06	44.5	COG0828	Ribosomal protein S21	67
644109949	337	57.31	1	337	1	340	0.0e+00	461	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
644109950	156	53.33	6	152	3	150	5.0e-43	166	COG1438	Arginine repressor	150
644109951	312	36.84	1	311	1	312	8.0e-68	250	COG0039	Malate/lactate dehydrogenase	313
644109952	87	70.73	1	82	1	82	9.0e-25	105	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
644109956	323	39.76	4	323	1	322	8.0e-83	300	COG0142	Geranylgeranyl pyrophosphate synthase	322
644109957	103	61.17	1	103	1	103	3.0e-34	136	COG0261	Ribosomal protein L21	103
644109958	85	75.29	1	85	1	84	1.0e-31	128	COG0211	Ribosomal protein L27	87
644109960	390	62.1	1	369	1	369	0.0e+00	539	COG0536	GTPase involved in cell partioning and DNA repair	369
644109961	477	46.33	1	475	1	469	0.0e+00	486	COG2027	D-alanyl-D-alanine carboxypeptidase	470
644109962	158	56.58	6	157	1	150	3.0e-45	174	COG0782	Transcription elongation factor, GreA/GreB family	151
644109963	97	58.76	2	97	1	97	5.0e-27	112	COG1534	RNA-binding protein YhbY	97
644109964	209	60.4	7	208	1	202	1.0e-76	279	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
644109965	646	61.56	6	601	1	596	0.0e+00	796	COG0465	ATP-dependent Zn proteases	596
644109966	277	50.38	15	277	8	269	4.0e-82	298	COG0294	Dihydropteroate synthase	274
644109969	233	50	9	231	1	224	3.0e-76	278	COG1136	ABC-type lipoprotein export system, ATPase component	226
644109976	81	75.38	5	69	7	71	2.0e-21	93.6	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
644109979	444	21.74	82	400	2	307	8.0e-08	52.3	COG0582	Integrase	309
644109982	308	31.82	33	308	39	324	1.0e-49	190	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
644109985	180	41.3	1	179	2	185	1.0e-50	192	COG1704	Uncharacterized conserved protein	185
644109986	349	44.13	1	346	2	339	4.0e-110	391	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
644109987	205	36.71	1	203	3	208	5.0e-26	111	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644109988	294	24.15	4	284	1	292	1.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
644109989	388	20.05	2	374	1	381	2.0e-10	60.6	COG2807	Cyanate permease	395
644109990	272	39.36	26	272	4	247	6.0e-64	237	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
644109991	254	33.99	2	254	6	257	4.0e-41	161	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
644109992	339	24.92	12	339	1	323	6.0e-31	128	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
644109996	231	29.44	1	230	2	229	6.0e-27	114	COG1011	FMN phosphatase YigB, HAD superfamily	229
644109997	379	35.16	1	360	31	394	9.0e-43	168	COG2814	Predicted arabinose efflux permease, MFS family	394
644109999	105	26	6	105	19	104	2.0e-07	47.5	COG0640	DNA-binding transcriptional regulator, ArsR family	110
644110005	180	77.78	1	180	2	181	5.0e-88	316	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
644110006	349	38.34	30	342	3	299	9.0e-97	347	COG1162	Putative ribosome biogenesis GTPase RsgA	301
644110007	342	32.13	8	283	1	238	1.0e-55	210	COG0688	Phosphatidylserine decarboxylase	239
644110008	1107	36.36	195	1093	1	816	0.0e+00	647	COG3264	Small-conductance mechanosensitive channel	835
644110009	325	70.46	1	325	1	322	0.0e+00	490	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
644110010	598	54.23	1	572	2	562	0.0e+00	647	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
644110011	245	47.88	6	240	1	234	5.0e-86	310	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
644110012	131	64.34	2	130	1	129	2.0e-43	168	COG3029	Fumarate reductase subunit C	129
644110013	118	74.58	1	118	1	118	2.0e-40	157	COG3080	Fumarate reductase subunit D	118
644110014	194	48.19	29	194	6	171	7.0e-54	203	COG3040	Bacterial lipocalin	174
644110017	188	48.85	1	131	1	131	7.0e-42	163	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
644110018	335	53.17	2	330	18	347	3.0e-124	438	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
644110020	549	54.27	49	538	4	446	0.0e+00	565	COG0166	Glucose-6-phosphate isomerase	446
644110021	458	36.95	12	458	2	446	2.0e-117	416	COG0527	Aspartokinase	447
644110022	565	44.34	19	548	5	530	0.0e+00	473	COG1283	Na+/phosphate symporter	533
644110023	484	36.42	11	483	5	461	3.0e-58	219	COG0471	Di- and tricarboxylate transporter	461
644110024	701	26.81	15	701	42	719	5.0e-69	256	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
644110025	318	29.41	198	315	1	119	1.0e-17	84.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644110026	1227	63.51	328	1192	1	842	0.0e+00	1224	COG1410	Methionine synthase I, cobalamin-binding domain	842
644110027	276	41.32	28	269	1	240	2.0e-63	236	COG1414	DNA-binding transcriptional regulator, IclR family	246
644110028	598	77.31	1	573	1	573	0.0e+00	939	COG4579	Isocitrate dehydrogenase kinase/phosphatase	578
644110029	435	74.94	1	435	1	433	0.0e+00	671	COG2224	Isocitrate lyase	433
644110030	532	49.54	1	531	6	541	0.0e+00	653	COG2225	Malate synthase	545
644110031	309	68.32	1	303	1	303	0.0e+00	505	COG1897	Homoserine trans-succinylase	307
644110033	424	48.82	2	423	1	413	2.0e-125	442	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
644110034	218	39.05	14	218	4	208	4.0e-44	171	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
644110035	262	55.25	1	257	1	257	5.0e-105	374	COG3622	Hydroxypyruvate isomerase	260
644110036	452	41.56	5	452	2	442	5.0e-72	265	COG2610	H+/gluconate symporter or related permease	442
644110037	552	34.45	153	515	24	408	1.0e-42	168	COG0840	Methyl-accepting chemotaxis protein	408
644110038	560	35.79	182	521	43	408	6.0e-43	169	COG0840	Methyl-accepting chemotaxis protein	408
644110039	396	38.33	2	396	53	453	6.0e-91	328	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644110040	233	61.7	1	233	3	237	4.0e-93	334	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
644110041	256	60.87	3	255	1	250	3.0e-97	348	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
644110042	424	50.15	87	411	4	310	3.0e-62	232	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
644110043	308	47.7	5	307	3	297	3.0e-58	218	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
644110044	370	40.17	17	369	1	361	3.0e-72	265	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
644110046	285	39.86	10	285	63	333	1.0e-69	256	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
644110047	322	43.67	22	321	2	296	2.0e-75	275	COG2177	Cell division protein FtsX	297
644110048	223	65.92	1	223	1	223	8.0e-96	342	COG2884	ABC-type ATPase involved in cell division	223
644110049	503	56.51	171	500	3	340	5.0e-114	405	COG0552	Signal recognition particle GTPase	340
644110050	191	53.76	12	191	1	186	6.0e-64	236	COG0742	16S rRNA G966 N2-methylase RsmD	187
644110051	92	60.44	1	91	2	91	2.0e-17	80.3	COG3776	Uncharacterized conserved protein YhhL, DUF1145 family	91
644110053	106	52.29	1	106	1	109	6.0e-40	155	COG4517	Uncharacterized protein	109
644110054	209	41.71	1	209	2	212	9.0e-30	123	COG3714	Uncharacterized membrane protein YhhN	212
644110055	787	41.62	92	786	1	711	0.0e+00	657	COG2217	Cation transport ATPase	713
644110056	80	45.33	7	80	3	77	5.0e-20	89.5	COG0425	TusA-related sulfurtransferase	78
644110057	225	43.89	1	215	14	233	3.0e-44	172	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
644110059	398	19.59	6	389	1	383	2.0e-10	60.6	COG2814	Predicted arabinose efflux permease, MFS family	394
644110060	338	28.04	29	322	1	289	3.0e-41	162	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
644110061	310	32.49	5	305	1	297	5.0e-49	188	COG0524	Sugar or nucleoside kinase, ribokinase family	311
644110062	505	23.49	22	445	6	409	9.0e-39	154	COG0612	Predicted Zn-dependent peptidase	438
644110063	430	52.78	2	409	1	405	8.0e-107	381	COG1301	Na+/H+-dicarboxylate symporter	415
644110064	383	27.63	232	374	27	176	6.0e-08	52	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644110069	245	25.2	1	237	2	251	4.0e-21	94.9	COG1192	Cellulose biosynthesis protein BcsQ	259
644110070	899	26.43	222	686	1	431	5.0e-51	196	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
644110072	371	50.56	4	354	4	351	2.0e-90	325	COG3405	Endo-1,4-beta-D-glucanase Y	360
644110074	560	32.56	1	553	1	552	2.0e-101	363	COG2831	Hemolysin activation/secretion protein	554
644110079	580	49.91	16	580	6	539	0.0e+00	614	COG0405	Gamma-glutamyltranspeptidase	539
644110082	416	78.37	1	416	1	416	0.0e+00	728	COG3977	Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase	417
644110083	147	40.14	1	147	1	135	1.0e-39	155	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
644110085	173	48.26	1	172	1	161	7.0e-40	156	COG1142	Fe-S-cluster-containing hydrogenase component 2	165
644110086	247	26.03	1	208	2	219	2.0e-19	89.3	COG2091	Phosphopantetheinyl transferase	223
644110087	445	60.65	12	441	3	434	2.0e-122	432	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
644110088	221	33.04	3	217	1	221	6.0e-39	154	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
644110091	247	41.13	11	241	8	217	3.0e-47	181	COG0765	ABC-type amino acid transport system, permease component	222
644110092	278	34.56	1	263	2	272	6.0e-39	154	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644110093	331	33.33	11	317	4	298	4.0e-49	188	COG2990	Uncharacterized protein VirK/YbjX	300
644110094	403	56.84	13	392	21	400	3.0e-96	345	COG3135	Predicted benzoate:H+ symporter BenE	402
644110095	188	34.12	9	92	2	86	7.0e-09	53.9	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
644110096	242	39.41	6	240	5	240	2.0e-47	182	COG0704	Phosphate uptake regulator	240
644110097	257	65.75	4	257	1	253	3.0e-127	448	COG1117	ABC-type phosphate transport system, ATPase component	253
644110098	295	52.26	15	294	4	289	5.0e-73	267	COG0581	ABC-type phosphate transport system, permease component	292
644110099	319	45.71	7	316	9	310	1.0e-74	273	COG0573	ABC-type phosphate transport system, permease component	310
644110100	346	37.57	1	326	12	318	2.0e-60	226	COG0226	ABC-type phosphate transport system, periplasmic component	318
644110102	408	42.41	1	408	2	412	6.0e-110	391	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644110103	243	40.87	1	243	4	251	6.0e-44	171	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644110104	160	47.5	1	157	6	157	8.0e-30	123	COG4706	Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain	161
644110105	385	32.05	1	381	4	409	9.0e-70	257	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644110107	773	48.08	19	773	10	788	0.0e+00	611	COG4258	Predicted exporter	788
644110108	201	19.4	1	201	9	199	5.0e-08	51.1	COG2834	Outer membrane lipoprotein-sorting protein	211
644110109	140	24.8	9	132	6	128	9.0e-23	99.2	COG0824	Acyl-CoA thioesterase FadM	137
644110110	570	51.6	251	562	3	305	6.0e-93	335	COG4261	Predicted acyltransferase, LPLAT superfamily	309
644110111	129	26.21	28	120	43	145	5.0e-09	53.7	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
644110112	451	23.63	27	451	37	524	2.0e-37	150	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
644110113	186	45.21	2	185	6	193	4.0e-34	137	COG4648	Uncharacterized membrane protein	201
644110114	82	31.25	1	80	1	80	4.0e-09	53	COG0236	Acyl carrier protein	80
644110116	263	24.79	32	261	2	229	4.0e-19	88.4	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
644110120	610	52.94	1	610	1	597	0.0e+00	802	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
644110121	456	58.82	4	456	1	459	0.0e+00	672	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
644110123	139	53.38	4	135	3	135	2.0e-36	144	COG0355	FoF1-type ATP synthase, epsilon subunit	135
644110124	460	78.71	1	460	1	465	0.0e+00	837	COG0055	FoF1-type ATP synthase, beta subunit	468
644110125	287	59.09	5	287	1	286	6.0e-106	377	COG0224	FoF1-type ATP synthase, gamma subunit	287
644110126	513	65.89	1	513	1	502	0.0e+00	824	COG0056	FoF1-type ATP synthase, alpha subunit	504
644110127	177	44.38	1	176	1	178	4.0e-42	164	COG0712	FoF1-type ATP synthase, delta subunit	178
644110128	156	49.02	4	156	6	158	2.0e-18	85.3	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
644110129	79	37.18	1	78	1	78	1.0e-05	41.7	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
644110130	266	47.23	1	266	1	246	1.0e-53	203	COG0356	FoF1-type ATP synthase, membrane subunit a	246
644110131	127	53.12	1	127	2	128	1.0e-17	82.2	COG3312	FoF1-type ATP synthase assembly protein I	128
644110132	206	45.5	1	204	1	211	2.0e-61	228	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
644110133	629	66.4	3	626	1	621	0.0e+00	1019	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
644110134	147	31.37	1	146	1	151	3.0e-22	97.8	COG0716	Flavodoxin	151
644110135	153	35.57	6	153	5	153	3.0e-29	121	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644110136	330	75.45	1	330	1	330	0.0e+00	559	COG2502	Asparagine synthetase A	330
644110137	492	35.1	17	486	2	435	8.0e-102	364	COG2425	Uncharacterized protein, contains a von Willebrand factor type A (vWA) domain	437
644110138	499	29.56	1	309	5	320	1.0e-44	174	COG0714	MoxR-like ATPase	329
644110139	622	62.86	1	622	7	627	0.0e+00	861	COG3158	K+ transporter	627
644110140	449	31.29	130	449	8	327	9.0e-38	151	COG0642	Signal transduction histidine kinase	336
644110141	220	43.91	1	220	1	229	1.0e-55	209	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644110142	131	54.96	1	131	1	127	8.0e-35	138	COG3111	Predicted periplasmic protein YdeI with OB-fold, BOF family	128
644110143	139	64.75	1	139	1	135	7.0e-50	189	COG1869	D-ribose pyranose/furanose isomerase RbsD	135
644110144	501	56.85	1	493	5	499	0.0e+00	672	COG1129	ABC-type sugar transport system, ATPase component	500
644110145	322	54.43	10	322	1	311	7.0e-66	244	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
644110146	295	41.67	3	295	10	309	1.0e-47	183	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
644110147	308	42.36	5	307	1	310	3.0e-59	222	COG0524	Sugar or nucleoside kinase, ribokinase family	311
644110148	328	46.2	1	328	3	330	7.0e-100	357	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644110149	97	37.89	2	96	5	99	7.0e-10	55.6	COG0640	DNA-binding transcriptional regulator, ArsR family	110
644110150	764	47.8	23	764	7	699	0.0e+00	743	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
644110151	327	30.58	207	327	2	122	5.0e-19	88.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644110152	442	26.29	1	384	3	388	4.0e-44	172	COG2079	2-methylcitrate dehydratase PrpD	453
644110154	392	25.93	107	374	1	203	1.0e-14	74.7	COG0412	Dienelactone hydrolase	236
644110156	394	38.64	14	392	11	393	5.0e-47	181	COG2814	Predicted arabinose efflux permease, MFS family	394
644110157	364	23.98	1	364	53	386	3.0e-33	136	COG1680	CubicO group peptidase, beta-lactamase class C family	390
644110158	298	33.77	3	297	2	296	1.0e-37	150	COG0583	DNA-binding transcriptional regulator, LysR family	297
644110159	474	53.83	3	456	1	454	0.0e+00	503	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
644110160	629	45.12	203	629	1	403	1.0e-98	354	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
644110161	887	76.72	1	887	1	887	0.0e+00	1517	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
644110162	254	41.63	1	242	1	241	2.0e-43	169	COG2186	DNA-binding transcriptional regulator, FadR family	241
644110163	452	55.85	2	452	3	455	0.0e+00	539	COG1113	L-asparagine transporter and related permeases	462
644110164	477	40.95	1	460	4	467	3.0e-128	452	COG2211	Na+/melibiose symporter or related transporter	467
644110165	319	69.11	5	317	3	316	0.0e+00	509	COG3940	Beta-xylosidase, GH43 family	324
644110166	284	56.21	1	284	1	282	2.0e-74	272	COG3725	Membrane protein required for beta-lactamase induction	282
644110168	286	65.41	1	286	5	284	1.0e-81	296	COG3248	Nucleoside-specific outer membrane channel protein Tsx	284
644110169	296	55.4	22	295	5	277	1.0e-94	339	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
644110170	148	36.28	1	111	1	113	4.0e-20	90.8	COG4969	Tfp pilus assembly protein, major pilin PilA	125
644110171	498	45.38	15	489	21	500	0.0e+00	507	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
644110172	401	34.92	4	398	1	396	1.0e-86	313	COG1459	Type II secretory pathway, component PulF	397
644110173	346	24.88	141	345	4	168	1.0e-27	117	COG0516	IMP dehydrogenase/GMP reductase	170
644110174	208	42.71	1	199	1	199	2.0e-55	208	COG0237	Dephospho-CoA kinase	201
644110175	250	68.44	7	250	1	244	2.0e-90	325	COG4582	Cell division protein ZapD, interacts with FtsZ	244
644110176	64	62.9	1	62	1	62	2.0e-16	77	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
644110177	131	32.35	1	128	4	136	5.0e-15	73.5	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
644110178	900	62.58	3	892	2	822	0.0e+00	1131	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
644110180	175	29.63	2	163	1	162	3.0e-36	144	COG4701	Uncharacterized protein	162
644110181	310	70.53	6	307	1	300	0.0e+00	493	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
644110182	383	56.97	2	337	3	338	2.0e-102	366	COG0206	Cell division GTPase FtsZ	338
644110183	418	49.05	8	418	6	418	0.0e+00	481	COG0849	Cell division ATPase FtsA	418
644110184	281	33.58	1	265	3	265	2.0e-49	189	COG1589	Cell division septal protein FtsQ	269
644110185	306	50.94	1	306	1	317	4.0e-93	334	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
644110186	486	54.91	13	477	1	455	0.0e+00	609	COG0773	UDP-N-acetylmuramate-alanine ligase	459
644110187	363	45.66	6	353	1	355	2.0e-105	375	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
644110188	400	45.5	29	389	13	374	9.0e-86	310	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
644110189	438	48.68	1	438	2	447	0.0e+00	480	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
644110190	360	47.55	20	360	1	316	2.0e-63	236	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
644110191	453	48.13	2	450	1	451	0.0e+00	474	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
644110192	495	48.33	21	494	9	475	0.0e+00	496	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
644110193	587	39.43	8	566	2	598	0.0e+00	469	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
644110194	106	63.81	1	105	1	105	1.0e-30	124	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
644110195	314	57.99	1	314	1	314	1.0e-119	423	COG0275	16S rRNA C1402 N4-methylase RsmH	314
644110196	152	48.03	1	152	1	146	3.0e-46	177	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
644110199	253	61.67	13	252	2	240	2.0e-116	411	COG1126	ABC-type polar amino acid transport system, ATPase component	240
644110200	362	37	133	359	1	222	8.0e-49	188	COG0765	ABC-type amino acid transport system, permease component	222
644110201	392	59.64	4	392	10	397	0.0e+00	514	COG4597	ABC-type amino acid transport system, permease component	397
644110202	341	25.94	2	261	1	261	2.0e-28	120	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644110203	221	49.77	1	218	3	221	1.0e-56	213	COG0765	ABC-type amino acid transport system, permease component	222
644110204	255	38.11	1	253	3	267	4.0e-38	151	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644110206	133	49.28	1	132	3	140	3.0e-36	143	COG4405	Uncharacterized protein YhfF	140
644110208	281	39.08	4	177	6	176	3.0e-37	148	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
644110209	258	30.86	3	251	10	261	5.0e-43	168	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
644110210	98	90.82	1	98	1	98	2.0e-37	147	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
644110211	321	46.6	1	321	2	322	6.0e-98	350	COG0042	tRNA-dihydrouridine synthase	323
644110212	244	50	1	243	1	247	1.0e-74	273	COG3338	Carbonic anhydrase	250
644110213	295	52.51	1	293	2	300	4.0e-100	358	COG2264	Ribosomal protein L11 methylase PrmA	300
644110214	483	70.09	3	470	1	467	0.0e+00	592	COG4145	Na+/panthothenate symporter	473
644110215	80	72.5	1	80	1	80	2.0e-30	123	COG3924	Uncharacterized membrane protein YhdT	80
644110217	142	43.08	76	140	4	68	1.0e-10	58.8	COG3585	Molybdopterin-binding protein	69
644110218	345	29.39	42	313	49	316	9.0e-28	118	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
644110219	331	44.94	1	330	2	331	3.0e-48	186	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
644110220	252	41.46	8	252	4	248	3.0e-69	254	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
644110222	282	35.13	1	274	2	273	6.0e-64	237	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
644110223	655	19.06	1	655	12	699	5.0e-31	129	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
644110224	447	65.47	1	444	1	445	0.0e+00	640	COG0439	Biotin carboxylase	449
644110225	155	48	6	155	1	139	1.0e-26	112	COG0511	Biotin carboxyl carrier protein	140
644110226	150	62.76	6	150	2	146	4.0e-60	223	COG0757	3-dehydroquinate dehydratase	146
644110227	199	55.78	1	199	1	198	3.0e-43	168	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
644110228	333	43.64	18	304	1	271	3.0e-68	252	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
644110229	325	29.52	1	324	1	326	2.0e-56	212	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
644110230	624	24	379	623	6	254	8.0e-32	132	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644110231	347	69.77	5	346	1	342	0.0e+00	494	COG1077	Actin-like ATPase involved in cell morphogenesis	342
644110232	327	39.86	3	277	1	276	9.0e-74	270	COG1792	Cell shape-determining protein MreC	284
644110234	162	48.7	10	162	10	163	1.0e-25	109	COG2891	Cell shape-determining protein MreD	167
644110235	197	54.79	1	187	2	189	2.0e-62	231	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
644110236	489	50.92	4	489	3	483	0.0e+00	534	COG1530	Ribonuclease G or E	487
644110237	1259	52.41	1	1257	18	1269	0.0e+00	1264	COG3164	Uncharacterized conserved protein YhdP, contains DUF3971 and AsmA2 domains	1271
644110238	481	41.79	17	480	1	454	9.0e-119	420	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
644110240	305	27.7	1	290	6	295	2.0e-40	159	COG0583	DNA-binding transcriptional regulator, LysR family	297
644110242	321	34.76	6	308	1	348	3.0e-58	219	COG1566	Multidrug resistance efflux pump	352
644110243	662	27.18	10	661	1	663	1.0e-79	291	COG1289	Uncharacterized membrane protein YccC	674
644110244	484	49.15	14	481	1	467	0.0e+00	510	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644110245	183	70.65	1	183	1	184	3.0e-57	214	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
644110246	446	40.22	15	445	2	448	1.0e-96	347	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
644110247	136	32.09	1	127	19	151	8.0e-20	89.6	COG0782	Transcription elongation factor, GreA/GreB family	151
644110248	90	49.44	2	90	1	88	7.0e-19	85.2	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
644110249	285	61.46	1	282	1	286	2.0e-110	392	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
644110250	151	37.75	2	150	1	149	1.0e-26	112	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
644110251	95	56.7	1	95	1	97	1.0e-24	104	COG1544	Ribosome-associated translation inhibitor RaiA	110
644110252	477	53.65	1	477	1	444	0.0e+00	506	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
644110253	241	71.49	1	241	2	243	2.0e-112	398	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
644110256	217	58.53	1	217	6	222	1.0e-74	272	COG2011	ABC-type methionine transport system, permease component	222
644110257	271	57.74	9	271	6	268	2.0e-92	332	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
644110259	238	53.09	1	162	2	155	5.0e-51	194	COG1720	tRNA (Thr-GGU) A37 N-methylase	156
644110260	572	48.08	1	568	1	500	0.0e+00	602	COG0442	Prolyl-tRNA synthetase	500
644110261	330	45.25	27	328	38	342	4.0e-76	278	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
644110262	344	33.21	89	342	3	262	5.0e-34	138	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
644110263	208	54.63	4	206	1	205	7.0e-70	256	COG2518	Protein-L-isoaspartate O-methyltransferase	209
644110265	348	37.02	7	341	12	399	2.0e-81	295	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
644110266	165	67.3	1	159	1	159	3.0e-67	247	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
644110267	237	44.4	9	235	3	228	5.0e-66	244	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
644110268	111	51.65	1	91	24	114	4.0e-23	100	COG2919	Cell division protein FtsB	117
644110269	261	31.14	1	261	1	273	2.0e-32	132	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644110270	254	36.73	8	252	10	222	9.0e-55	206	COG0765	ABC-type amino acid transport system, permease component	222
644110271	240	67.08	1	240	2	240	1.0e-110	392	COG1126	ABC-type polar amino acid transport system, ATPase component	240
644110273	205	65.99	10	205	1	197	3.0e-85	307	COG0529	Adenylylsulfate kinase or related kinase	197
644110274	496	66.2	43	474	1	431	0.0e+00	677	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
644110275	302	39.03	1	302	11	261	5.0e-62	231	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
644110276	480	64.08	220	462	2	244	7.0e-89	321	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
644110277	459	24.63	26	417	36	432	1.0e-43	171	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644110278	344	31.5	218	344	2	124	3.0e-14	73	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644110279	345	46.33	1	336	4	339	1.0e-101	363	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
644110280	714	54.6	391	711	1	325	1.0e-111	397	COG0280	Phosphotransacetylase	327
644110281	244	40.59	13	244	7	243	2.0e-55	209	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
644110282	577	43.4	20	571	5	509	0.0e+00	529	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
644110283	609	56.11	17	609	1	587	0.0e+00	679	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
644110284	574	21.28	246	523	69	335	3.0e-11	64	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
644110285	246	26.18	14	243	16	248	5.0e-35	141	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644110287	430	24.88	5	427	13	432	1.0e-43	170	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
644110289	120	44.96	1	120	1	127	3.0e-30	123	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
644110290	223	37.44	1	223	2	212	2.0e-51	195	COG0602	Organic radical activating enzyme	212
644110291	327	23.32	71	293	11	212	1.0e-16	80.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644110292	248	40.32	6	247	9	249	2.0e-38	152	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644110293	379	41.62	32	379	5	354	8.0e-97	347	COG4225	Rhamnogalacturonyl hydrolase YesR	357
644110294	519	28.27	1	474	4	462	4.0e-74	272	COG2211	Na+/melibiose symporter or related transporter	467
644110295	296	24.48	1	289	1	288	9.0e-26	110	COG0583	DNA-binding transcriptional regulator, LysR family	297
644110296	472	33.71	3	445	31	468	2.0e-90	326	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644110297	225	29.33	20	225	11	183	4.0e-21	95.2	COG0693	Putative intracellular protease/amidase	188
644110298	358	26.9	14	324	9	316	9.0e-36	144	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
644110299	731	19.81	53	731	41	768	3.0e-29	124	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644110300	431	69.14	1	431	1	423	0.0e+00	629	COG0148	Enolase	423
644110301	545	67.77	3	543	1	533	0.0e+00	919	COG0504	CTP synthase (UTP-ammonia lyase)	533
644110308	165	36.84	14	162	2	153	4.0e-23	100	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644110309	338	27.57	1	338	51	391	3.0e-33	136	COG2814	Predicted arabinose efflux permease, MFS family	394
644110317	194	40.7	18	182	4	175	3.0e-40	158	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
644110318	460	42.55	1	369	26	401	1.0e-110	393	COG0513	Superfamily II DNA and RNA helicase	513
644110319	244	25.83	5	240	32	254	5.0e-24	104	COG0725	ABC-type molybdate transport system, periplasmic component	258
644110320	256	38.89	5	243	2	252	2.0e-60	225	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
644110321	339	43.4	4	337	2	334	9.0e-55	207	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
644110322	354	27.74	23	327	34	319	4.0e-45	175	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
644110323	341	22.9	15	335	3	334	4.0e-31	129	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
644110324	281	45.67	19	271	7	236	2.0e-32	132	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
644110326	164	31.85	4	160	24	179	2.0e-17	82.4	COG3149	Type II secretory pathway, component PulM	181
644110327	425	25.31	27	422	7	388	6.0e-42	165	COG3297	Type II secretory pathway, component PulL	390
644110328	328	37.15	1	320	1	316	2.0e-56	212	COG3156	Type II secretory pathway, component PulK	323
644110329	186	26.37	1	181	14	190	3.0e-22	98.1	COG4795	Type II secretory pathway, component PulJ	194
644110332	166	37.7	18	132	5	126	2.0e-16	78.9	COG2165	Type II secretory pathway, pseudopilin PulG	149
644110333	408	43.98	1	407	1	397	9.0e-102	363	COG1459	Type II secretory pathway, component PulF	397
644110334	498	53.35	7	497	12	500	0.0e+00	551	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
644110335	684	32.56	36	631	16	561	8.0e-99	355	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
644110337	659	26.84	47	634	3	532	7.0e-65	242	COG5434	Polygalacturonase	542
644110338	522	29.81	203	517	95	344	1.0e-38	154	COG3866	Pectate lyase	345
644110341	413	42.31	14	395	5	390	1.0e-106	380	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
644110342	326	27.73	1	326	3	355	5.0e-44	171	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644110343	284	34.4	3	279	2	278	3.0e-60	225	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
644110344	817	25.9	9	800	22	808	8.0e-96	345	COG3264	Small-conductance mechanosensitive channel	835
644110348	566	18.71	14	282	114	389	3.0e-09	57	COG0732	Restriction endonuclease S subunit	391
644110349	490	32.16	1	487	5	489	2.0e-83	303	COG0286	Type I restriction-modification system, DNA methylase subunit	489
644110350	477	25.71	4	345	1	348	8.0e-50	191	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
644110351	292	26.62	24	287	13	286	1.0e-45	177	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
644110354	321	24.92	6	320	64	383	5.0e-29	121	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
644110356	433	38.5	5	425	10	444	3.0e-118	418	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
644110357	508	37.92	149	508	24	408	9.0e-45	175	COG0840	Methyl-accepting chemotaxis protein	408
644110360	340	52.79	1	338	1	337	7.0e-117	413	COG1135	ABC-type methionine transport system, ATPase component	339
644110361	219	57.48	3	216	9	222	8.0e-66	243	COG2011	ABC-type methionine transport system, permease component	222
644110362	358	28.53	1	349	13	366	3.0e-62	232	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644110364	269	44.03	1	266	5	268	9.0e-69	253	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
644110366	466	21.21	16	457	12	409	3.0e-30	126	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644110367	308	29.87	1	296	1	293	1.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
644110368	359	32.39	1	353	6	356	5.0e-69	255	COG1377	Flagellar biosynthesis protein FlhB	363
644110369	267	32.49	3	239	1	235	6.0e-29	121	COG4791	Type III secretory pathway, component EscT	259
644110370	86	44.44	2	82	5	85	9.0e-10	55.2	COG4794	Type III secretory pathway, component EscS	89
644110371	217	48.82	7	217	3	213	3.0e-53	201	COG4790	Type III secretory pathway, component EscR	214
644110372	385	20.51	245	361	24	135	4.0e-07	49.6	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
644110375	455	50	16	450	10	438	0.0e+00	512	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
644110377	700	42.16	7	692	1	689	0.0e+00	634	COG4789	Type III secretory pathway, component EscV	689
644110380	180	28.57	21	179	16	176	2.0e-20	92.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644110382	213	35.89	5	212	1	209	2.0e-45	175	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644110384	526	27.18	14	514	16	512	1.0e-77	284	COG4943	Environmental sensor c-di-GMP phosphodiesterase, contains periplasmic CSS-motif sensor and cytoplasmic EAL domain	524
644110387	255	39.75	7	244	9	238	5.0e-47	181	COG4669	Type III secretory pathway, lipoprotein EscJ	246
644110392	689	25.66	24	555	7	568	6.0e-61	229	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
644110403	221	33.64	1	218	5	223	4.0e-31	128	COG1802	DNA-binding transcriptional regulator, GntR family	230
644110404	565	33.63	18	565	8	554	3.0e-106	379	COG2831	Hemolysin activation/secretion protein	554
644110407	163	56.79	1	162	3	163	4.0e-51	193	COG0440	Acetolactate synthase, small subunit	163
644110408	572	51.42	3	564	1	549	0.0e+00	680	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
644110409	601	41.74	8	601	16	610	0.0e+00	630	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
644110410	532	50.6	3	414	1	409	8.0e-129	454	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
644110411	363	55.07	2	362	1	348	1.0e-130	459	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
644110412	466	60.77	1	465	1	422	0.0e+00	645	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
644110413	200	59.5	1	199	1	190	2.0e-82	298	COG0066	3-isopropylmalate dehydratase small subunit	191
644110414	103	28.28	1	99	5	103	4.0e-09	52.9	COG4392	Branched-chain amino acid transport protein	107
644110415	222	29.41	3	222	15	235	1.0e-32	133	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
644110416	278	29.51	157	277	1	122	8.0e-19	88	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644110417	539	36.61	198	538	43	408	5.0e-47	182	COG0840	Methyl-accepting chemotaxis protein	408
644110418	79	34.29	10	79	11	80	1.0e-08	51.6	COG5302	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid	80
644110421	552	48.94	1	549	1	564	0.0e+00	571	COG4533	DNA-binding transcriptional regulator SgrR  of sgrS sRNA, contains a MarR-type HTH domain and a periplasmic-type solute-binding domain	564
644110423	301	29.57	3	298	2	295	1.0e-39	157	COG0583	DNA-binding transcriptional regulator, LysR family	297
644110424	338	64.65	13	337	5	335	1.0e-128	453	COG4143	ABC-type thiamine transport system, periplasmic component	336
644110425	535	36.76	1	534	1	537	1.0e-89	324	COG1178	ABC-type Fe3+ transport system, permease component	540
644110426	236	64.35	1	230	1	230	3.0e-88	318	COG3840	ABC-type thiamine transport system, ATPase component	231
644110427	540	26.85	33	539	1	549	1.0e-80	294	COG3507	Beta-xylosidase	549
644110428	554	47.91	4	552	3	550	0.0e+00	618	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
644110430	256	35.32	8	206	8	208	1.0e-33	136	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
644110431	552	39.11	372	544	1	178	2.0e-37	151	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644110432	788	33.95	4	788	4	788	0.0e+00	642	COG0417	DNA polymerase elongation subunit (family B)	792
644110433	967	27.22	59	944	8	835	3.0e-66	247	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
644110434	217	44.04	7	217	73	289	2.0e-59	221	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644110435	296	26.13	69	290	1	174	3.0e-24	106	COG1076	DnaJ-domain-containing proteins 1	174
644110436	787	43.09	1	787	1	784	0.0e+00	681	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
644110437	431	21.45	1	340	1	320	4.0e-18	86.3	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
644110438	333	56.27	8	331	4	329	2.0e-121	428	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
644110439	272	52.51	11	268	4	258	7.0e-91	327	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
644110440	125	64.8	1	125	2	126	1.0e-49	188	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
644110441	285	23.77	146	263	34	155	1.0e-11	64.3	COG0639	Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family	155
644110443	174	42.07	10	154	2	145	5.0e-20	90.6	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
644110444	301	22.71	7	299	1	293	2.0e-21	96.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
644110445	160	46.43	3	160	2	167	1.0e-41	162	COG0262	Dihydrofolate reductase	167
644110446	156	47.1	4	156	1	155	3.0e-31	127	COG3610	Uncharacterized membrane protein YjjB, DUF3815 family	156
644110447	257	38.93	3	243	8	250	3.0e-59	222	COG2966	Uncharacterized membrane protein YjjP, DUF1212 family	250
644110448	204	35.75	1	204	2	206	1.0e-28	119	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644110450	229	44.4	1	229	4	234	4.0e-48	184	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
644110452	581	39.22	72	439	1	384	1.0e-75	277	COG0458	Carbamoylphosphate synthase large subunit	400
644110453	514	70.2	13	408	1	393	0.0e+00	574	COG0458	Carbamoylphosphate synthase large subunit	400
644110454	382	63.03	3	378	2	366	0.0e+00	594	COG0505	Carbamoylphosphate synthase small subunit	368
644110455	273	56.55	4	270	1	266	2.0e-99	355	COG0289	Dihydrodipicolinate reductase	266
644110456	316	66.78	1	295	2	294	2.0e-127	449	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
644110457	157	35.86	5	149	3	146	1.0e-37	148	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
644110458	170	49.07	1	158	3	159	7.0e-37	146	COG0597	Lipoprotein signal peptidase	167
644110459	921	51.77	1	915	16	933	0.0e+00	1271	COG0060	Isoleucyl-tRNA synthetase	933
644110460	281	51.46	2	275	34	303	1.0e-87	316	COG0196	FAD synthase	304
644110461	87	63.22	1	87	1	87	1.0e-14	71.5	COG0268	Ribosomal protein S20	88
644110462	304	20.49	4	288	1	286	4.0e-25	108	COG0583	DNA-binding transcriptional regulator, LysR family	297
644110463	395	62.08	1	385	7	388	2.0e-118	419	COG3004	Na+/H+ antiporter NhaA	390
644110464	378	64.29	1	375	1	371	0.0e+00	515	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
644110465	635	59.41	1	605	4	579	0.0e+00	661	COG0443	Molecular chaperone DnaK (HSP70)	579
644110466	191	64.71	6	186	19	205	1.0e-52	199	COG1584	Succinate-acetate transporter protein	207
644110467	445	19.5	65	423	56	387	3.0e-10	60.2	COG2814	Predicted arabinose efflux permease, MFS family	394
644110468	195	44.57	4	177	8	168	2.0e-46	179	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
644110469	281	37.8	112	274	10	172	3.0e-33	136	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644110470	317	38.22	5	314	1	238	2.0e-67	249	COG0176	Transaldolase	239
644110471	257	68.48	1	257	1	253	5.0e-96	344	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
644110472	429	34.6	1	409	1	404	3.0e-99	355	COG0498	Threonine synthase	411
644110473	309	43.04	1	309	3	298	2.0e-102	366	COG0083	Homoserine kinase	299
644110474	819	45.02	1	460	3	445	0.0e+00	464	COG0527	Aspartokinase	447
644110475	228	43.35	5	228	7	238	9.0e-59	220	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
644110476	238	38.03	4	235	1	228	1.0e-51	196	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644110477	160	65.38	1	156	3	155	1.0e-59	222	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
644110478	295	36.63	6	106	21	121	2.0e-21	96.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644110479	216	36.41	1	193	2	195	1.0e-41	163	COG0406	Broad specificity phosphatase PhoE	208
644110480	179	47.19	1	173	1	175	2.0e-51	195	COG1986	Non-canonical (house-cleaning) NTP pyrophosphatase, all-alpha NTP-PPase family	175
644110481	115	64.58	10	105	5	100	4.0e-29	120	COG2973	Trp operon repressor	103
644110482	644	28.2	346	637	1	296	6.0e-36	146	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
644110484	555	48.15	3	536	1	529	0.0e+00	569	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644110485	567	40.16	175	525	33	408	4.0e-45	176	COG0840	Methyl-accepting chemotaxis protein	408
644110486	302	35.81	5	291	3	292	6.0e-36	144	COG0583	DNA-binding transcriptional regulator, LysR family	297
644110487	333	29.17	1	332	1	325	3.0e-53	202	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
644110488	410	41.87	8	336	1	324	5.0e-89	321	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
644110489	219	55.07	1	219	1	227	2.0e-77	281	COG0120	Ribose 5-phosphate isomerase	227
644110490	297	26.4	4	296	1	297	3.0e-21	96.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
644110491	242	45.45	2	240	4	243	5.0e-58	217	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
644110492	204	54.46	1	202	1	202	2.0e-58	218	COG1279	Arginine exporter protein ArgO	202
644110493	286	34.98	13	286	26	308	7.0e-40	157	COG0668	Small-conductance mechanosensitive channel	316
644110494	358	34.5	17	356	5	284	1.0e-87	317	COG0191	Fructose/tagatose bisphosphate aldolase	286
644110495	387	57.14	1	386	2	395	0.0e+00	495	COG0126	3-phosphoglycerate kinase	395
644110496	338	51.19	2	336	1	332	5.0e-120	424	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
644110499	343	33.43	1	340	1	350	4.0e-79	288	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
644110500	315	48.33	6	244	11	250	2.0e-72	265	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
644110501	433	50.61	26	433	13	420	2.0e-94	339	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
644110502	143	37.61	35	143	2	110	2.0e-18	84.6	COG0607	Rhodanese-related sulfurtransferase	110
644110503	156	59.48	3	155	5	157	4.0e-58	217	COG1952	Preprotein translocase subunit SecB	157
644110504	339	55.62	7	335	3	329	2.0e-124	438	COG0240	Glycerol-3-phosphate dehydrogenase	329
644110505	273	58.55	76	268	2	194	7.0e-71	260	COG1045	Serine acetyltransferase	194
644110507	299	23.18	1	282	9	292	5.0e-08	52.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
644110508	311	29	2	294	1	296	2.0e-34	139	COG0583	DNA-binding transcriptional regulator, LysR family	297
644110509	754	64.05	422	752	1	329	0.0e+00	463	COG0620	Methionine synthase II (cobalamin-independent)	330
644110510	542	36.03	131	513	1	408	2.0e-49	190	COG0840	Methyl-accepting chemotaxis protein	408
644110511	553	35.29	131	513	1	408	9.0e-50	191	COG0840	Methyl-accepting chemotaxis protein	408
644110512	275	40.16	37	275	2	236	8.0e-59	220	COG0412	Dienelactone hydrolase	236
644110513	256	62.45	1	253	1	248	8.0e-89	319	COG2820	Uridine phosphorylase	248
644110514	260	33.6	12	255	1	248	7.0e-38	150	COG2365	Protein tyrosine/serine phosphatase	249
644110515	879	59.04	2	879	3	910	0.0e+00	1218	COG2352	Phosphoenolpyruvate carboxylase	910
644110516	462	26.2	97	454	2	372	3.0e-48	186	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
644110517	416	27.53	13	400	3	372	4.0e-60	225	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644110518	237	32.38	7	211	12	221	1.0e-33	136	COG2188	DNA-binding transcriptional regulator, GntR family	236
644110519	381	33.01	1	381	10	409	6.0e-66	244	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644110520	334	50.58	1	333	2	342	7.0e-123	433	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
644110521	257	41.67	1	256	2	264	7.0e-66	243	COG0548	Acetylglutamate kinase	265
644110522	457	57.33	1	457	3	458	0.0e+00	641	COG0165	Argininosuccinate lyase	459
644110523	520	45.89	72	472	29	423	1.0e-94	340	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
644110524	251	59.17	13	251	1	238	5.0e-86	310	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
644110525	207	46.34	1	205	1	200	3.0e-49	188	COG3165	Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain	204
644110526	546	46.27	1	518	2	517	0.0e+00	525	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
644110527	86	32.56	1	85	1	86	1.0e-12	64.6	COG1826	Sec-independent protein translocase protein TatA	94
644110528	197	42.86	1	91	1	90	2.0e-16	79.6	COG1826	Sec-independent protein translocase protein TatA	94
644110529	250	53.75	1	250	2	254	4.0e-63	234	COG0805	Sec-independent protein secretion pathway component TatC	255
644110530	260	38.31	1	259	3	256	3.0e-70	258	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
644110531	340	60	7	336	3	330	0.0e+00	535	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
644110532	162	24.57	1	161	2	176	2.0e-24	105	COG0250	Transcription antitermination factor NusG	178
644110533	498	59.02	4	491	1	476	0.0e+00	694	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
644110534	233	32.27	1	219	5	216	1.0e-44	173	COG0543	NAD(P)H-flavin reductase	252
644110535	387	45.79	1	387	1	392	1.0e-92	333	COG0183	Acetyl-CoA acetyltransferase	392
644110536	729	42	314	612	4	300	8.0e-91	328	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
644110537	443	20.81	10	438	8	375	2.0e-36	146	COG0006	Xaa-Pro aminopeptidase	384
644110538	203	41.33	1	195	1	195	6.0e-47	180	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
644110539	179	60	1	174	1	174	2.0e-63	235	COG4635	Protoporphyrinogen IX oxidase, menaquinone-dependent (flavodoxin domain)	175
644110547	249	47.52	11	249	8	249	2.0e-75	275	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
644110550	416	22.3	1	414	6	414	2.0e-10	60.5	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
644110551	376	44.97	1	376	5	372	1.0e-117	416	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
644110553	357	68.27	4	355	1	338	0.0e+00	580	COG1088	dTDP-D-glucose 4,6-dehydratase	340
644110554	420	52.94	5	420	11	424	0.0e+00	546	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
644110555	376	60.8	1	372	4	371	0.0e+00	522	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
644110556	348	47.35	7	346	9	339	1.0e-97	350	COG3765	LPS O-antigen chain length determinant protein, WzzB/FepE family	347
644110557	360	27.86	1	313	5	318	1.0e-42	167	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
644110558	419	79.71	1	419	4	421	0.0e+00	733	COG1158	Transcription termination factor Rho	422
644110560	429	40.97	1	427	21	445	1.0e-110	393	COG0513	Superfamily II DNA and RNA helicase	513
644110561	498	43.06	7	487	4	492	3.0e-130	459	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
644110562	673	47.35	1	650	1	655	0.0e+00	616	COG0210	Superfamily I DNA or RNA helicase	655
644110564	494	48.69	3	481	1	491	1.0e-93	337	COG0591	Na+/proline symporter	493
644110565	295	33.44	3	295	2	292	9.0e-35	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
644110566	220	36.41	1	188	2	192	2.0e-32	132	COG2085	Predicted dinucleotide-binding enzyme	211
644110567	492	41.04	19	362	1	338	3.0e-124	439	COG0059	Ketol-acid reductoisomerase	338
644110568	296	34.24	1	294	1	289	1.0e-38	153	COG0583	DNA-binding transcriptional regulator, LysR family	297
644110570	247	25.66	5	225	4	226	2.0e-19	90.1	COG5587	Uncharacterized conserved protein, DUF2461 family	228
644110571	514	51.15	9	351	1	347	1.0e-115	410	COG1171	Threonine dehydratase	347
644110572	616	54.94	1	614	8	575	0.0e+00	799	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
644110573	308	45.24	5	296	1	284	2.0e-76	279	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
644110574	86	61.63	1	86	1	86	2.0e-22	97	COG3978	Acetolactate synthase small subunit, contains ACT domain	86
644110575	548	52.36	1	543	2	549	0.0e+00	642	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
644110576	508	60.49	15	499	1	490	0.0e+00	625	COG0606	Predicted ATPase with chaperone activity	490
644110577	112	83.04	1	112	1	112	1.0e-42	164	COG3085	Uncharacterized conserved protein YifE, UPF0438 family	112
644110578	275	30.07	1	267	1	284	5.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
644110579	320	36.36	1	318	4	316	3.0e-46	179	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
644110580	336	41.69	9	325	1	309	9.0e-48	184	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
644110581	506	49.2	1	498	3	500	0.0e+00	580	COG1129	ABC-type sugar transport system, ATPase component	500
644110582	318	34.92	5	315	15	321	5.0e-45	174	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
644110586	481	39.22	24	479	5	453	2.0e-110	392	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
644110587	454	31.28	19	453	2	453	5.0e-76	278	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
644110588	140	37.23	3	139	1	137	1.0e-25	109	COG0848	Biopolymer transport protein ExbD	137
644110589	246	35.98	9	222	1	214	8.0e-37	147	COG0811	Biopolymer transport protein ExbB/TolQ	216
644110590	293	23.4	57	291	15	243	2.0e-13	69.8	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
644110591	317	38.68	2	314	10	322	1.0e-55	210	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
644110592	173	25.81	12	163	17	171	9.0e-17	80.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644110593	791	23.14	112	791	17	719	5.0e-63	236	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
644110594	600	39.75	15	560	31	586	1.0e-128	453	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
644110596	254	48.95	7	242	2	233	4.0e-73	268	COG3910	Predicted ATPase	233
644110597	979	21.92	439	979	2	577	7.0e-26	113	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
644110598	75	63.16	1	75	1	76	1.0e-19	88.2	COG3813	Uncharacterized protein	84
644110599	205	23.86	11	205	14	203	2.0e-23	102	COG0400	Predicted esterase	207
644110600	556	37.25	134	516	1	408	4.0e-50	192	COG0840	Methyl-accepting chemotaxis protein	408
644110601	392	49.26	3	392	2	392	2.0e-92	333	COG0183	Acetyl-CoA acetyltransferase	392
644110602	215	55.81	1	211	5	219	2.0e-74	272	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
644110603	218	52.29	1	218	1	218	4.0e-73	267	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
644110606	440	46.15	1	440	1	432	2.0e-103	369	COG2851	Mg2+/citrate symporter	433
644110607	322	33.55	26	321	1	297	3.0e-41	162	COG0583	DNA-binding transcriptional regulator, LysR family	297
644110609	224	37.79	2	212	26	241	1.0e-44	172	COG1876	LD-carboxypeptidase LdcB, LAS superfamily	241
644110610	375	32.91	1	375	11	408	2.0e-82	299	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644110611	125	33.87	1	122	1	116	1.0e-25	108	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
644110612	322	21.77	77	322	2	239	5.0e-20	92	COG5571	Uncharacterized protein YhjY, contains autotransporter beta-barrel domain	239
644110615	236	58.33	4	231	2	228	4.0e-87	314	COG1794	Aspartate/glutamate racemase	230
644110616	69	71.64	3	69	1	67	2.0e-25	107	COG1278	Cold shock protein, CspA family	67
644110617	127	42.4	1	124	1	125	1.0e-19	88.3	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
644110619	321	67.64	13	321	1	306	0.0e+00	505	COG0320	Lipoate synthase	306
644110620	224	60.98	6	208	11	215	6.0e-82	297	COG0321	Lipoate-protein ligase B	221
644110621	87	76.4	1	87	2	90	1.0e-33	134	COG2921	Putative lipoic acid-binding regulatory protein	90
644110622	403	50.25	10	402	1	389	7.0e-120	424	COG1686	D-alanyl-D-alanine carboxypeptidase	389
644110623	372	37.07	5	230	7	233	1.0e-42	167	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
644110624	370	44.35	11	370	9	379	2.0e-80	293	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
644110625	634	36.98	6	617	1	593	0.0e+00	482	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
644110626	156	52.26	1	155	1	155	7.0e-63	232	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
644110627	105	52.38	1	105	1	105	4.0e-37	146	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
644110628	229	45.67	22	228	6	195	1.0e-55	210	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
644110629	341	36.83	4	334	1	333	2.0e-65	242	COG1466	DNA polymerase III, delta subunit	334
644110630	184	55.87	4	181	3	178	2.0e-47	181	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
644110631	860	53.58	1	859	1	814	0.0e+00	1109	COG0495	Leucyl-tRNA synthetase	814
644110634	67	70.15	1	67	1	65	9.0e-23	98.4	COG2879	Uncharacterized short protein YbdD, DUF466 family	65
644110635	285	37.41	2	285	33	322	1.0e-60	227	COG0523	GTPase, G3E family	323
644110637	159	55.7	1	158	1	155	4.0e-41	160	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
644110638	272	37.41	4	265	12	289	3.0e-58	218	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
644110639	907	44.52	172	905	3	713	0.0e+00	736	COG2217	Cation transport ATPase	713
644110640	135	35.85	1	105	1	106	5.0e-19	86.7	COG0789	DNA-binding transcriptional regulator, MerR family	124
644110641	151	44.76	7	149	1	140	3.0e-29	121	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
644110642	304	41	1	293	2	291	1.0e-54	207	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
644110643	86	26.67	5	86	6	95	7.0e-11	58.9	COG0633	Ferredoxin	102
644110644	376	36.1	2	371	1	346	7.0e-94	337	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
644110645	761	35.57	41	748	1	651	0.0e+00	598	COG0209	Ribonucleotide reductase alpha subunit	696
644110646	239	61.54	6	236	8	240	5.0e-94	337	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
644110647	517	44.31	113	513	9	389	4.0e-110	391	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
644110648	879	60.28	1	842	1	803	0.0e+00	1082	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
644110650	216	33.17	4	204	1	202	9.0e-40	157	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644110651	765	23.23	288	540	91	335	1.0e-17	85.6	COG0642	Signal transduction histidine kinase	336
644110653	389	20	40	379	33	377	3.0e-06	46.7	COG2814	Predicted arabinose efflux permease, MFS family	394
644110654	440	39.45	8	439	1	423	1.0e-102	366	COG1169	Isochorismate synthase EntC	423
644110655	560	47.97	1	557	1	563	0.0e+00	638	COG1165	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase	566
644110656	253	22.39	5	250	16	282	2.0e-13	69.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644110657	285	76.24	6	285	1	282	0.0e+00	522	COG0447	1,4-Dihydroxy-2-naphthoyl-CoA synthase	282
644110658	323	70.4	1	321	1	321	0.0e+00	493	COG1441	O-succinylbenzoate synthase	321
644110659	484	26.74	1	470	10	527	2.0e-73	269	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644110662	402	41.56	1	398	7	415	7.0e-62	231	COG0814	Amino acid permease	415
644110663	397	40.82	1	239	1	242	2.0e-68	253	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
644110664	286	52.84	6	286	23	304	3.0e-82	298	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
644110665	256	30.92	1	255	5	257	2.0e-40	159	COG0300	Short-chain dehydrogenase	265
644110666	197	37.44	9	195	4	214	2.0e-27	115	COG2755	Lysophospholipase L1 or related esterase	216
644110667	243	70.67	19	243	4	228	7.0e-89	320	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
644110668	809	49.52	1	807	6	829	0.0e+00	861	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
644110669	329	28.62	3	314	2	303	6.0e-15	75.3	COG3547	Transposase	303
644110670	191	31.46	8	175	10	187	8.0e-25	106	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644110671	704	23.96	13	704	29	719	6.0e-66	246	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
644110674	208	62.74	1	208	2	203	1.0e-76	279	COG0605	Superoxide dismutase	204
644110675	277	50.99	25	275	13	264	8.0e-84	303	COG1526	Formate dehydrogenase assembly factor FdhD	266
644110676	511	44.06	24	506	1	472	0.0e+00	518	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644110677	330	49.24	1	330	1	331	1.0e-75	276	COG3274	Surface polysaccharide O-acyltransferase, integral membrane enzyme	332
644110678	485	42.31	1	485	5	498	2.0e-128	452	COG1070	Sugar (pentulose or hexulose) kinase	502
644110679	440	78.03	1	437	2	438	0.0e+00	776	COG2115	Xylose isomerase	438
644110680	331	63.13	1	331	1	339	5.0e-117	414	COG4213	ABC-type xylose transport system, periplasmic component	341
644110681	513	50.3	1	504	5	500	0.0e+00	619	COG1129	ABC-type sugar transport system, ATPase component	500
644110682	393	58.44	14	393	10	394	3.0e-120	425	COG4214	ABC-type xylose transport system, permease component	394
644110683	392	23.6	18	278	72	329	1.0e-31	130	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644110684	191	30.81	1	171	1	185	2.0e-22	99.1	COG0693	Putative intracellular protease/amidase	188
644110685	448	35.22	8	428	1	403	2.0e-130	459	COG0137	Argininosuccinate synthase	403
644110686	216	34.34	1	196	1	198	2.0e-50	192	COG3916	N-acyl-L-homoserine lactone synthetase	209
644110687	242	42.19	175	238	2	65	3.0e-10	59.2	COG2771	DNA-binding transcriptional regulator, CsgD family	65
644110688	400	40.55	2	396	32	398	8.0e-84	304	COG4677	Pectin methylesterase and related acyl-CoA thioesterases	405
644110689	331	39.94	6	320	15	327	2.0e-79	289	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
644110690	129	39.81	22	127	1	105	5.0e-11	60.3	COG0607	Rhodanese-related sulfurtransferase	110
644110693	113	65.74	1	108	1	108	1.0e-27	114	COG3136	Uncharacterized membrane protein, GlpM family	111
644110694	337	32.19	16	335	5	320	2.0e-58	219	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
644110695	342	25.8	1	334	1	313	3.0e-38	152	COG0451	Nucleoside-diphosphate-sugar epimerase	314
644110697	428	22.25	1	426	1	436	7.0e-65	241	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
644110699	374	30.5	39	235	60	257	7.0e-21	95.2	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
644110700	379	21.14	10	354	2	321	9.0e-17	81.7	COG3239	Fatty acid desaturase	343
644110701	366	19.71	68	341	63	303	3.0e-15	76.3	COG3239	Fatty acid desaturase	343
644110703	479	44.09	7	478	2	469	0.0e+00	480	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644110704	386	47.48	7	382	2	355	1.0e-107	383	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
644110705	166	36.9	5	166	17	182	3.0e-31	127	COG2320	GrpB domain, predicted nucleotidyltransferase, UPF0157 family	185
644110706	389	26.88	10	354	17	351	3.0e-34	139	COG0628	Predicted PurR-regulated permease PerM	355
644110711	127	40	5	123	7	126	6.0e-25	106	COG3654	Prophage maintenance system killer protein	132
644110715	287	58.28	1	287	1	290	3.0e-91	328	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
644110716	302	24.08	1	294	1	297	5.0e-30	125	COG0583	DNA-binding transcriptional regulator, LysR family	297
644110717	315	51.75	1	314	1	307	3.0e-88	318	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
644110718	273	42.96	1	269	1	268	5.0e-60	224	COG2362	D-aminopeptidase	274
644110719	358	39.77	26	352	1	347	9.0e-74	270	COG3191	L-aminopeptidase/D-esterase	348
644110720	299	52.67	20	299	8	288	9.0e-74	270	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644110721	254	47.73	1	254	53	316	6.0e-73	267	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644110722	114	49.56	2	114	1	113	7.0e-33	132	COG0698	Ribose 5-phosphate isomerase RpiB	151
644110724	460	22.43	23	449	1	405	9.0e-19	88.4	COG2223	Nitrate/nitrite transporter NarK	417
644110725	590	39.09	1	329	1	322	4.0e-75	275	COG2376	Dihydroxyacetone kinase	323
644110726	259	34.77	3	252	1	247	3.0e-53	202	COG0149	Triosephosphate isomerase	251
644110727	275	20.82	1	244	3	260	4.0e-13	68.7	COG1082	Sugar phosphate isomerase/epimerase	274
644110729	320	39.81	6	318	8	319	9.0e-86	310	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
644110731	759	57.01	1	433	13	432	0.0e+00	596	COG0281	Malic enzyme	432
644110732	424	39.51	18	420	6	415	5.0e-65	242	COG0814	Amino acid permease	415
644110733	150	55.7	1	149	2	148	9.0e-53	199	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
644110734	310	67.44	1	300	4	303	0.0e+00	477	COG0408	Coproporphyrinogen III oxidase	303
644110735	141	35.66	1	126	12	152	1.0e-12	66.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
644110736	316	23.83	105	310	30	243	3.0e-15	76.3	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
644110738	924	25.12	31	460	13	430	9.0e-42	166	COG0612	Predicted Zn-dependent peptidase	438
644110739	557	39.93	2	556	23	593	0.0e+00	511	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
644110741	299	40.68	1	299	22	343	5.0e-81	294	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
644110742	342	75.07	1	340	1	341	0.0e+00	546	COG4150	ABC-type sulfate transport system, periplasmic component	341
644110743	284	56.04	10	282	2	274	3.0e-72	265	COG0555	ABC-type sulfate transport system, permease component	274
644110744	288	62.98	19	280	15	276	6.0e-102	363	COG4208	ABC-type sulfate transport system, permease component	287
644110745	293	48.82	3	289	4	300	1.0e-100	359	COG0031	Cysteine synthase	300
644110746	650	52.73	5	222	1	220	8.0e-79	288	COG1136	ABC-type lipoprotein export system, ATPase component	226
644110747	399	28.53	13	386	17	358	9.0e-30	124	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644110748	226	47.37	1	226	1	226	3.0e-60	224	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644110749	455	25.53	126	455	3	332	4.0e-37	149	COG0642	Signal transduction histidine kinase	336
644110750	169	55.77	16	169	1	156	2.0e-48	185	COG2190	Phosphotransferase system IIA component	156
644110751	575	63.53	1	573	2	574	0.0e+00	810	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
644110752	85	50	1	84	1	84	6.0e-24	102	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
644110753	322	61.17	4	308	1	300	5.0e-112	397	COG0031	Cysteine synthase	300
644110754	276	64.71	29	266	6	243	6.0e-85	307	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
644110755	351	45.89	1	351	1	324	2.0e-79	289	COG3115	Cell division protein ZipA, interacts with FtsZ	324
644110756	417	23.46	1	407	4	441	2.0e-24	106	COG0531	Amino acid transporter	466
644110757	93	52.22	1	90	10	99	2.0e-20	90.8	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
644110758	217	62.19	14	214	4	203	5.0e-80	290	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
644110759	286	55.79	1	95	5	99	4.0e-33	135	COG3615	Uncharacterized protein/domain, possibly involved in tellurite resistance	99
644110761	321	34.73	5	166	3	157	8.0e-27	114	COG0835	Chemotaxis signal transduction protein	165
644110762	729	45.16	5	729	1	699	0.0e+00	727	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
644110764	414	22.63	37	394	37	382	2.0e-18	87.2	COG2814	Predicted arabinose efflux permease, MFS family	394
644110765	279	31.34	44	254	1	200	2.0e-27	116	COG0625	Glutathione S-transferase	211
644110766	117	48.72	1	117	2	118	5.0e-35	139	COG4683	Uncharacterized protein	120
644110768	334	42.86	11	333	6	332	1.0e-77	283	COG1171	Threonine dehydratase	347
644110769	112	31.13	1	106	8	99	3.0e-10	57.1	COG0640	DNA-binding transcriptional regulator, ArsR family	110
644110770	130	42.72	17	119	13	115	3.0e-25	107	COG1733	DNA-binding transcriptional regulator, HxlR family	120
644110772	211	26.67	1	203	1	204	2.0e-13	69.2	COG2910	Putative NADH-flavin reductase	211
644110773	411	24.08	20	365	16	362	6.0e-18	85.6	COG2814	Predicted arabinose efflux permease, MFS family	394
644110774	162	26.85	15	116	1	108	5.0e-12	64	COG0789	DNA-binding transcriptional regulator, MerR family	124
644110775	478	41.86	4	474	3	454	0.0e+00	558	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
644110779	179	81.67	1	179	40	215	5.0e-58	217	COG3122	Uncharacterized conserved protein YaiL, DUF2058 family	215
644110780	343	31.71	1	339	1	330	1.0e-69	257	COG0620	Methionine synthase II (cobalamin-independent)	330
644110783	111	32.14	1	110	1	104	7.0e-11	59.1	COG2105	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family	120
644110784	296	29.77	5	290	1	298	4.0e-45	175	COG1893	Ketopantoate reductase	307
644110785	242	27.47	3	93	1	91	6.0e-13	68.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
644110787	239	27.63	1	239	6	258	1.0e-29	123	COG0300	Short-chain dehydrogenase	265
644110788	420	42.24	1	416	9	424	2.0e-122	432	COG2907	Predicted NAD/FAD-binding protein	447
644110789	240	38.15	3	240	7	254	2.0e-56	212	COG3496	Uncharacterized conserved protein, DUF1365 family	261
644110790	406	44.76	120	405	3	283	9.0e-83	300	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
644110794	319	60.74	157	319	1	162	2.0e-55	209	COG3272	Uncharacterized conserved protein YbgA, DUF1722 family	163
644110796	284	34.22	60	284	20	229	5.0e-22	98.5	COG2801	Transposase InsO and inactivated derivatives	232
644110799	303	34.84	19	234	21	232	1.0e-33	137	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
644110801	183	11.19	5	134	1	132	1.0e-05	43.1	COG3335	Transposase	132
644110802	349	20.77	2	349	51	415	3.0e-13	69.5	COG0738	Fucose permease	422
644110803	196	33.14	15	186	11	182	2.0e-22	98.9	COG3226	DNA-binding transcriptional regulator YbjK	204
644110804	453	22.49	105	450	12	379	6.0e-43	168	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
644110805	475	43.16	6	472	1	460	0.0e+00	486	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
644110807	217	27.53	1	216	11	257	1.0e-26	112	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
644110808	309	36.62	1	309	1	310	1.0e-61	230	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
644110809	476	54.95	2	473	5	479	0.0e+00	655	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
644110810	128	50.39	1	128	3	129	5.0e-34	136	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
644110811	154	57.24	1	151	1	151	5.0e-53	200	COG1781	Aspartate carbamoyltransferase, regulatory subunit	153
644110812	311	54.6	1	306	1	312	2.0e-113	402	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
644110813	154	39.22	1	153	1	153	1.0e-46	178	COG2731	Beta-galactosidase, beta subunit	154
644110818	141	76.81	4	141	1	135	9.0e-40	155	COG3076	Regulator of RNase E activity RraB	135
644110819	167	22.86	9	148	1	122	9.0e-09	53.3	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
644110820	393	37.06	1	393	4	364	2.0e-79	289	COG4269	Uncharacterized membrane protein YjgN, DUF898 family	364
644110821	345	20.22	97	344	39	299	1.0e-16	80.7	COG0501	Zn-dependent protease with chaperone function	302
644110822	366	26.93	23	356	1	366	2.0e-46	180	COG2021	Homoserine acetyltransferase	368
644110823	539	35.99	177	515	45	408	1.0e-46	180	COG0840	Methyl-accepting chemotaxis protein	408
644110824	592	41.77	31	592	1	554	0.0e+00	511	COG2831	Hemolysin activation/secretion protein	554
644110825	2361	17.09	448	1374	36	1005	1.0e-09	60.5	COG3210	Large exoprotein involved in heme utilization or adhesion	1013
644110828	180	48.89	2	180	29	205	2.0e-55	208	COG1859	RNA:NAD 2'-phosphotransferase, TPT1/KptA family	211
644110833	216	28.57	1	211	1	222	3.0e-27	114	COG2323	Uncharacterized membrane protein YcaP, DUF421 family	224
644110834	951	55.25	1	950	1	877	0.0e+00	1238	COG0525	Valyl-tRNA synthetase	877
644110835	149	50.67	1	148	1	143	9.0e-39	152	COG2927	DNA polymerase III, chi subunit	144
644110836	503	51.2	1	498	1	485	0.0e+00	593	COG0260	Leucyl aminopeptidase	485
644110837	371	35.28	1	349	2	361	3.0e-60	226	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
644110838	358	35.64	2	358	1	362	2.0e-64	239	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
644110841	373	55.2	1	373	9	383	2.0e-121	428	COG2850	Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain	383
644110843	397	18.25	98	381	5	284	5.0e-08	52.6	COG0842	ABC-type multidrug transport system, permease component	286
644110846	403	36.46	2	392	1	385	2.0e-81	296	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
644110847	392	35.53	1	390	3	386	9.0e-74	270	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
644110848	441	32.86	13	430	3	384	2.0e-76	280	COG0006	Xaa-Pro aminopeptidase	384
644110849	195	60.62	3	195	1	186	6.0e-64	236	COG3079	Uncharacterized conserved protein YgfB, UPF0149 family	186
644110850	109	42.86	3	107	1	105	3.0e-21	93.4	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
644110851	215	38.78	19	212	1	190	4.0e-45	174	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
644110852	417	76.47	225	411	2	187	4.0e-78	285	COG3172	Nicotinamide riboside kinase	187
644110853	460	61.3	1	460	1	456	0.0e+00	675	COG1066	Predicted ATP-dependent serine protease	456
644110854	325	49.53	107	317	1	212	9.0e-59	220	COG0560	Phosphoserine phosphatase	212
644110855	231	63.21	1	211	1	211	3.0e-66	244	COG3726	Uncharacterized membrane protein affecting hemolysin expression	214
644110857	529	74	3	529	2	528	0.0e+00	923	COG4108	Peptide chain release factor RF-3	528
644110858	202	37.72	37	202	31	195	1.0e-26	113	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
644110861	265	42.97	7	261	2	256	2.0e-77	282	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
644110862	425	56.26	1	423	1	403	0.0e+00	479	COG1972	Nucleoside permease NupC	404
644110863	238	34.42	22	236	13	226	1.0e-42	166	COG2977	4'-phosphopantetheinyl transferase EntD (siderophore biosynthesis)	228
644110864	657	34.38	15	657	6	699	8.0e-124	438	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
644110865	416	25.07	25	391	30	382	7.0e-23	101	COG2814	Predicted arabinose efflux permease, MFS family	394
644110866	398	41.38	22	392	46	422	5.0e-110	391	COG1169	Isochorismate synthase EntC	423
644110867	541	62.22	1	537	4	541	0.0e+00	760	COG1021	Non-ribosomal peptide synthetase component E (peptide arylation enzyme)	542
644110868	291	67.96	1	206	1	206	2.0e-88	319	COG1535	Isochorismate hydrolase	218
644110869	1047	29.73	232	878	1	642	4.0e-89	323	COG1020	Non-ribosomal peptide synthetase component F	642
644110870	256	39.08	10	253	1	251	1.0e-41	163	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644110871	2117	35.97	303	951	4	640	1.0e-109	392	COG1020	Non-ribosomal peptide synthetase component F	642
644110872	700	33.73	133	626	149	642	3.0e-70	260	COG1020	Non-ribosomal peptide synthetase component F	642
644110873	502	18.86	14	478	1	457	3.0e-16	80.2	COG1538	Outer membrane protein TolC	457
644110876	272	62.41	1	266	1	261	2.0e-108	385	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
644110877	151	49.31	6	149	1	144	3.0e-42	164	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
644110878	401	48.77	2	398	1	405	3.0e-123	435	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
644110880	307	26.42	6	297	1	297	2.0e-37	150	COG0583	DNA-binding transcriptional regulator, LysR family	297
644110881	131	52.8	2	126	1	124	2.0e-27	114	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
644110882	366	76.26	1	358	1	358	0.0e+00	594	COG2933	23S rRNA C2498 (ribose-2'-O)-methylase RlmM	358
644110883	260	38.76	4	246	12	267	2.0e-56	212	COG0258	5'-3' exonuclease	310
644110884	454	32.68	136	338	4	201	8.0e-45	175	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
644110885	282	69.12	2	137	1	136	6.0e-56	211	COG2904	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, N-terminal domain	137
644110887	558	28.65	21	558	5	532	1.0e-78	287	COG1574	Predicted amidohydrolase YtcJ	535
644110888	140	27.03	19	129	12	120	3.0e-09	54.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
644110889	116	54.63	1	108	1	108	4.0e-27	113	COG3098	Uncharacterized conserved protein YqcC, DUF446 family	109
644110890	261	35.4	2	224	78	288	7.0e-53	200	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644110891	151	29.61	1	147	1	150	2.0e-22	98.5	COG0716	Flavodoxin	151
644110893	275	54.64	2	274	1	271	5.0e-88	317	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
644110894	937	58.53	66	933	2	866	0.0e+00	1123	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
644110895	264	51.95	1	254	1	255	2.0e-96	345	COG0024	Methionine aminopeptidase	255
644110896	241	64.26	1	235	1	234	5.0e-101	360	COG0052	Ribosomal protein S2	252
644110897	283	61.49	1	282	1	296	2.0e-90	325	COG0264	Translation elongation factor EF-Ts	296
644110898	241	62.87	5	240	1	237	8.0e-94	336	COG0528	Uridylate kinase	238
644110899	185	62.16	1	185	3	187	5.0e-68	250	COG0233	Ribosome recycling factor	187
644110900	398	58.9	1	398	1	385	0.0e+00	554	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
644110901	253	52.65	1	245	1	245	1.0e-91	329	COG0020	Undecaprenyl pyrophosphate synthase	245
644110902	285	36.17	1	281	1	264	3.0e-38	152	COG0575	CDP-diglyceride synthetase	265
644110904	809	46.36	1	809	1	766	0.0e+00	772	COG4775	Outer membrane protein assembly factor BamA	766
644110905	165	50	1	165	1	168	5.0e-26	110	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
644110906	340	55.46	1	337	1	338	2.0e-110	392	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
644110907	151	58.5	7	151	3	147	3.0e-48	184	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
644110908	262	65.77	3	262	1	260	9.0e-114	403	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
644110909	383	55.38	5	381	1	380	0.0e+00	485	COG0763	Lipid A disaccharide synthetase	381
644110910	198	62.11	13	198	2	191	2.0e-69	255	COG0164	Ribonuclease HII	199
644110911	1160	52.06	3	1158	1	1139	0.0e+00	1415	COG0587	DNA polymerase III, alpha subunit	1139
644110914	420	53.57	1	417	1	416	0.0e+00	490	COG3075	Anaerobic glycerol-3-phosphate dehydrogenase	421
644110915	556	39.15	10	537	12	532	0.0e+00	475	COG0578	Glycerol-3-phosphate dehydrogenase	532
644110917	449	53.11	1	447	1	446	0.0e+00	537	COG2271	Sugar phosphate permease	448
644110918	355	37.84	22	354	1	257	3.0e-46	179	COG0584	Glycerophosphoryl diester phosphodiesterase	257
644110919	266	35.07	1	265	2	262	1.0e-58	220	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
644110920	345	33.76	37	344	1	294	3.0e-55	209	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
644110921	206	38.65	1	204	1	207	4.0e-32	131	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644110922	207	32.86	1	207	2	207	2.0e-27	115	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644110923	608	59.66	13	604	5	589	0.0e+00	784	COG0514	Superfamily II DNA helicase RecQ	590
644110924	290	60.51	32	290	42	317	9.0e-93	333	COG2829	Outer membrane phospholipase A	317
644110925	162	30.46	12	161	1	136	7.0e-15	73.5	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
644110926	309	62.8	3	295	2	293	6.0e-89	320	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
644110927	345	47.65	2	339	10	349	1.0e-64	240	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
644110928	316	34.37	1	316	4	322	4.0e-65	241	COG0598	Mg2+ and Co2+ transporter CorA	322
644110929	248	33.47	12	246	3	218	7.0e-42	163	COG1878	Kynurenine formamidase	218
644110930	720	46.67	8	653	1	655	0.0e+00	624	COG0210	Superfamily I DNA or RNA helicase	655
644110931	238	26.5	10	238	4	226	4.0e-26	111	COG1011	FMN phosphatase YigB, HAD superfamily	229
644110932	311	69.23	11	309	1	299	7.0e-127	447	COG4973	Site-specific recombinase XerC	299
644110933	234	52.47	12	232	2	218	8.0e-58	217	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
644110934	274	55.84	1	274	1	272	3.0e-106	378	COG0253	Diaminopimelate epimerase	272
644110935	61	39.62	7	59	1	53	7.0e-07	45.4	COG5567	Predicted small periplasmic lipoprotein YifL (function unknown0	58
644110936	106	57.14	1	105	1	105	5.0e-37	145	COG1965	Iron-binding protein CyaY, frataxin homolog	106
644110937	390	22.06	48	386	54	385	4.0e-06	46	COG2814	Predicted arabinose efflux permease, MFS family	394
644110938	852	75.64	1	847	1	851	0.0e+00	1304	COG3072	Adenylate cyclase	853
644110939	313	64.69	6	307	4	306	2.0e-122	431	COG0181	Porphobilinogen deaminase	307
644110940	246	32.65	1	245	2	241	6.0e-46	177	COG1587	Uroporphyrinogen-III synthase	248
644110941	376	53.74	1	372	1	371	3.0e-85	308	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
644110942	399	57.11	3	396	1	394	4.0e-121	428	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
644110943	385	42.26	10	380	10	390	4.0e-107	381	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
644110944	253	59.09	1	242	2	239	7.0e-98	350	COG1126	ABC-type polar amino acid transport system, ATPase component	240
644110945	223	44.5	12	220	15	221	8.0e-51	193	COG0765	ABC-type amino acid transport system, permease component	222
644110947	263	29.67	1	262	1	272	6.0e-35	141	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644110948	180	18.75	3	145	12	154	2.0e-06	45.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
644110949	332	40.87	1	321	114	436	9.0e-87	314	COG0015	Adenylosuccinate lyase	438
644110950	534	69.66	12	534	1	524	0.0e+00	774	COG0033	Phosphoglucomutase	524
644110951	142	47.89	1	142	1	140	2.0e-24	104	COG2510	Uncharacterized membrane protein	140
644110952	226	44.69	5	226	3	227	5.0e-58	217	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644110953	920	52.95	4	916	1	889	0.0e+00	1050	COG2205	K+-sensing histidine kinase KdpD	890
644110954	191	57.45	1	186	2	189	3.0e-59	221	COG2156	K+-transporting ATPase, c chain	190
644110955	714	73.58	28	714	1	681	0.0e+00	1082	COG2216	High-affinity K+ transport system, ATPase chain B	681
644110956	562	65.18	3	557	1	559	0.0e+00	701	COG2060	K+-transporting ATPase, A chain	560
644110958	319	72.22	158	319	1	161	1.0e-59	223	COG3272	Uncharacterized conserved protein YbgA, DUF1722 family	163
644110959	492	51.06	7	476	3	461	0.0e+00	537	COG0415	Deoxyribodipyrimidine photolyase	461
644110960	247	44.4	1	247	1	250	1.0e-75	276	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
644110961	218	56.02	6	218	1	216	2.0e-72	265	COG2049	Allophanate hydrolase subunit 1	223
644110962	314	51.58	2	312	1	311	1.0e-108	386	COG1984	Allophanate hydrolase subunit 2	314
644110963	245	58	1	245	2	251	3.0e-89	321	COG1540	Lactam utilization protein B (function unknown)	252
644110964	215	60.68	2	207	1	206	9.0e-77	279	COG2039	Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)	207
644110965	263	32.73	1	263	1	273	2.0e-58	219	COG0266	Formamidopyrimidine-DNA glycosylase	273
644110966	141	17.69	4	133	1	138	5.0e-06	43.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644110967	428	54.77	27	423	1	386	0.0e+00	499	COG0372	Citrate synthase	390
644110968	129	44.09	7	129	1	127	3.0e-17	80.7	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
644110969	115	46.09	1	115	2	116	4.0e-20	89.9	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
644110970	588	56.84	3	559	2	546	0.0e+00	663	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
644110971	238	56.72	1	237	1	231	1.0e-84	306	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
644110972	935	64.16	6	934	1	906	0.0e+00	1441	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
644110973	408	50.49	2	407	1	404	1.0e-117	416	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
644110974	388	64.36	1	388	1	387	0.0e+00	548	COG0045	Succinyl-CoA synthetase, beta subunit	387
644110975	290	71.13	1	290	1	291	5.0e-125	440	COG0074	Succinyl-CoA synthetase, alpha subunit	293
644110977	379	47.09	1	374	1	346	2.0e-93	336	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
644110979	97	65.98	1	97	1	97	4.0e-30	123	COG3790	Predicted membrane protein, encoded in cydAB operon	97
644110980	134	38.06	1	134	1	133	3.0e-33	133	COG0824	Acyl-CoA thioesterase FadM	137
644110981	225	44.44	6	221	1	216	8.0e-53	200	COG0811	Biopolymer transport protein ExbB/TolQ	216
644110982	141	39.01	1	141	2	135	9.0e-29	119	COG0848	Biopolymer transport protein ExbD	137
644110984	176	62.35	7	176	1	170	1.0e-60	226	COG4160	ABC-type arginine/histidine transport system, permease component	228
644110985	229	56.14	1	225	2	229	2.0e-76	278	COG4215	ABC-type arginine transport system, permease component	230
644110986	259	32.72	1	258	1	269	9.0e-37	147	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644110987	190	63.16	1	188	2	188	3.0e-76	277	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
644110988	505	55.1	1	485	4	470	0.0e+00	637	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
644110989	166	44.31	1	166	1	167	1.0e-30	126	COG1286	Uncharacterized membrane protein, required for colicin V production	182
644110990	252	49.8	1	250	1	226	2.0e-37	149	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
644110991	422	44.26	7	420	1	427	3.0e-129	455	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
644110992	305	65.62	1	286	1	288	3.0e-123	435	COG0777	Acetyl-CoA carboxylase beta subunit	294
644110994	220	42.16	14	216	1	202	1.0e-37	150	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
644110995	283	56.15	24	283	3	262	4.0e-94	338	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
644110996	336	44.35	4	331	1	334	3.0e-94	338	COG0136	Aspartate-semialdehyde dehydrogenase	334
644110997	378	37.42	1	286	2	314	1.0e-53	204	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
644111000	405	45.65	1	404	2	412	3.0e-118	418	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644111001	675	41.43	5	255	5	252	3.0e-84	306	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
644111003	181	80.23	5	181	3	179	1.0e-87	315	COG3101	Elongation factor P hydroxylase (EF-P beta-lysylation pathway)	180
644111004	266	36.58	6	256	2	257	2.0e-21	96.6	COG0730	Uncharacterized membrane protein YfcA	258
644111005	281	59.78	8	280	5	280	1.0e-103	369	COG3770	Murein endopeptidase	284
644111006	361	61.58	2	361	1	366	0.0e+00	555	COG0082	Chorismate synthase	369
644111007	310	40.69	14	301	1	279	2.0e-65	242	COG2890	Methylase of polypeptide chain release factors	280
644111008	180	48.37	1	178	1	184	8.0e-52	196	COG2840	DNA-nicking endonuclease, Smr domain	184
644111009	160	39.62	1	153	2	158	2.0e-33	135	COG2062	Phosphohistidine phosphatase SixA	163
644111010	182	30.29	11	182	10	174	2.0e-07	49.2	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
644111011	178	31.18	9	178	10	174	5.0e-13	67.7	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
644111012	261	22.88	1	235	3	211	3.0e-27	115	COG3121	P pilus assembly protein, chaperone PapD	235
644111013	788	24.84	46	783	61	835	6.0e-114	405	COG3188	Outer membrane usher protein FimD/PapC	835
644111014	335	25.71	166	333	2	173	2.0e-10	60.4	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
644111015	738	44.52	328	606	2	283	8.0e-88	318	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
644111016	437	35.09	12	435	1	391	4.0e-63	235	COG0183	Acetyl-CoA acetyltransferase	392
644111019	744	52.72	9	740	1	700	0.0e+00	917	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
644111020	449	39.35	20	436	3	432	2.0e-111	396	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
644111021	931	32.76	177	526	1	335	2.0e-40	161	COG0642	Signal transduction histidine kinase	336
644111022	811	37.42	12	811	1	764	0.0e+00	520	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
644111023	208	47.06	1	202	8	203	2.0e-54	205	COG0437	Fe-S-cluster-containing dehydrogenase component	203
644111024	258	34.42	1	258	2	276	2.0e-36	146	COG3302	DMSO reductase anchor subunit	281
644111025	197	35.35	1	194	7	204	4.0e-37	147	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
644111027	381	67.2	1	378	1	378	0.0e+00	527	COG1929	Glycerate kinase	378
644111028	294	50.35	1	285	1	286	4.0e-81	294	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
644111029	256	54.33	4	256	2	255	2.0e-94	338	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
644111030	446	27.43	8	415	1	371	5.0e-58	218	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644111031	450	27.62	8	420	1	372	2.0e-57	216	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644111032	450	22.01	18	435	27	433	6.0e-27	115	COG2271	Sugar phosphate permease	448
644111034	524	47.91	119	524	5	381	7.0e-130	457	COG2721	Altronate dehydratase	381
644111036	496	34.31	179	494	66	406	6.0e-45	175	COG0840	Methyl-accepting chemotaxis protein	408
644111040	73	75.71	1	70	1	69	2.0e-22	97.3	COG3530	Uncharacterized conserved protein, DUF3820 family	71
644111041	684	59.85	14	683	7	667	0.0e+00	946	COG0272	NAD-dependent DNA ligase	667
644111042	478	62.79	1	473	1	465	0.0e+00	723	COG2870	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase	467
644111043	951	53.03	1	950	12	956	0.0e+00	1093	COG1391	Glutamine synthetase adenylyltransferase	963
644111044	445	46.74	1	441	1	431	1.0e-96	347	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
644111045	633	35.41	216	628	1	383	5.0e-72	265	COG0672	High-affinity Fe2+/Pb2+ permease	383
644111046	175	69.1	1	175	1	178	1.0e-72	265	COG3470	Uncharacterized protein probably involved in high-affinity Fe2+ transport	179
644111047	465	47.78	1	405	1	405	2.0e-125	442	COG4393	Uncharacterized membrane protein	405
644111048	429	22.56	15	429	2	419	3.0e-28	119	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
644111049	379	21.71	7	379	1	408	1.0e-24	108	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
644111050	238	48.23	17	233	1	226	6.0e-75	273	COG1136	ABC-type lipoprotein export system, ATPase component	226
644111051	165	29.91	27	141	7	123	5.0e-12	64.2	COG0526	Thiol-disulfide isomerase or thioredoxin	127
644111052	325	22.08	1	307	5	287	5.0e-06	45.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
644111053	277	29.84	149	271	1	121	3.0e-16	79.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644111054	317	31.21	1	296	1	292	3.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
644111056	438	49.41	1	421	1	407	4.0e-105	375	COG1301	Na+/H+-dicarboxylate symporter	415
644111057	367	33.96	1	314	2	313	7.0e-49	188	COG0371	Glycerol dehydrogenase or related enzyme, iron-containing ADH family	360
644111058	288	35.06	38	287	12	258	7.0e-46	177	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
644111059	288	47.58	12	259	2	243	6.0e-75	274	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
644111060	341	23.19	9	332	6	321	3.0e-22	99.5	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
644111061	354	36.69	23	353	11	343	2.0e-79	289	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
644111062	337	33.04	10	335	10	334	9.0e-47	181	COG4521	ABC-type taurine transport system, periplasmic component	334
644111063	257	37.89	1	256	6	257	4.0e-48	185	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
644111064	267	49.22	9	264	1	248	3.0e-89	321	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
644111065	337	53.19	1	327	1	319	5.0e-92	331	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
644111066	238	31.2	6	237	4	229	2.0e-40	159	COG1794	Aspartate/glutamate racemase	230
644111067	446	55.63	2	444	1	436	0.0e+00	538	COG2704	Anaerobic C4-dicarboxylate transporter	436
644111068	451	25.59	28	448	38	457	3.0e-40	159	COG1538	Outer membrane protein TolC	457
644111069	452	20.43	38	434	20	346	2.0e-14	74.2	COG1566	Multidrug resistance efflux pump	352
644111070	619	55.18	6	572	7	575	0.0e+00	720	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
644111072	792	17.82	49	792	71	768	4.0e-28	120	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644111074	240	31.34	14	228	15	230	2.0e-30	125	COG1802	DNA-binding transcriptional regulator, GntR family	230
644111075	245	50.44	6	232	3	230	3.0e-61	228	COG4126	Asp/Glu/hydantoin racemase	230
644111076	319	22.62	16	314	3	267	2.0e-25	110	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
644111078	451	46.59	11	449	3	436	4.0e-106	378	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
644111079	548	39.19	1	444	6	426	4.0e-74	272	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
644111080	236	40.87	1	225	1	229	5.0e-53	201	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644111081	499	31.49	211	496	45	327	1.0e-33	137	COG0642	Signal transduction histidine kinase	336
644111083	183	32.18	2	175	1	155	3.0e-11	61.4	COG4960	Flp pilus assembly protein, protease CpaA	168
644111084	314	27.04	1	314	1	269	6.0e-19	88.5	COG3745	Flp pilus assembly protein CpaB	276
644111085	479	36.05	26	461	2	415	4.0e-76	279	COG4964	Flp pilus assembly protein, secretin CpaC	455
644111086	228	23.74	11	216	3	214	4.0e-07	48.5	COG5461	Type IV pilus biogenesis protein CpaD/CtpE	224
644111087	399	26.2	133	399	93	359	5.0e-17	82.3	COG4963	Flp pilus assembly protein, ATPase CpaE	366
644111088	467	55.3	90	438	12	355	2.0e-110	392	COG4962	Pilus assembly protein, ATPase of CpaF family	355
644111089	326	28.71	8	324	4	307	1.0e-34	140	COG4965	Flp pilus assembly protein TadB	309
644111095	3183	22.07	1437	1783	14	332	8.0e-09	58.4	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
644111101	489	30.33	2	484	17	509	2.0e-66	246	COG0659	Sulfate permease or related transporter, MFS superfamily	554
644111102	211	38.24	1	203	1	199	4.0e-42	164	COG0288	Carbonic anhydrase	207
644111103	649	34.46	274	633	23	408	5.0e-41	162	COG0840	Methyl-accepting chemotaxis protein	408
644111104	903	33.37	32	902	32	917	0.0e+00	698	COG0474	Magnesium-transporting ATPase (P-type)	917
644111105	525	34.46	160	516	26	408	8.0e-40	158	COG0840	Methyl-accepting chemotaxis protein	408
644111106	104	56.19	1	104	1	105	2.0e-35	140	COG3254	L-rhamnose mutarotase	105
644111107	274	26.54	7	264	6	214	3.0e-34	139	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
644111108	420	79.9	1	418	1	418	0.0e+00	713	COG4806	L-rhamnose isomerase	419
644111109	496	26.88	1	483	1	500	9.0e-83	301	COG1070	Sugar (pentulose or hexulose) kinase	502
644111111	277	32.52	153	275	2	124	2.0e-18	86.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644111112	96	32.14	8	91	4	83	1.0e-08	51.1	COG3905	Predicted transcriptional regulator	83
644111114	569	48.55	20	567	3	533	0.0e+00	564	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
644111115	288	44.44	6	282	4	282	2.0e-55	209	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644111116	318	40.06	11	311	5	314	3.0e-65	241	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644111117	537	28.16	11	536	13	553	2.0e-67	250	COG0747	ABC-type transport system, periplasmic component	556
644111118	204	60.61	4	200	2	176	5.0e-54	204	COG3477	Uncharacterized membrane protein YagU, involved in acid resistance, DUF1440 family	176
644111120	168	59.15	1	164	4	166	1.0e-43	168	COG2862	Uncharacterized membrane protein YqhA	169
644111121	345	65.79	1	342	2	339	0.0e+00	509	COG2130	NADPH-dependent curcumin reductase CurA	340
644111124	159	38.85	1	153	1	153	3.0e-33	134	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
644111126	430	49.06	7	430	2	425	2.0e-115	409	COG0823	Periplasmic component of the Tol biopolymer transport system	425
644111127	170	32.43	1	170	3	187	8.0e-36	143	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
644111128	258	52.31	1	255	1	258	7.0e-59	220	COG1729	Periplasmic TolA-binding protein (function unknown)	262
644111131	238	36.13	1	238	2	228	9.0e-40	157	COG1811	Uncharacterized membrane protein YqgA, affects biofilm formation	228
644111133	353	47.51	4	343	2	324	8.0e-120	423	COG0379	Quinolinate synthase	324
644111134	241	44.3	4	239	8	222	7.0e-47	180	COG3201	Nicotinamide riboside transporter PnuC	222
644111135	320	50.69	3	289	11	296	2.0e-80	292	COG1230	Co/Zn/Cd efflux system component	296
644111136	351	68.95	1	350	1	351	0.0e+00	591	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
644111137	250	65.22	3	232	1	230	2.0e-101	362	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
644111138	1045	52.5	1	1037	1	1020	0.0e+00	1252	COG3696	Cu/Ag efflux pump CusA	1027
644111139	500	26.14	90	387	32	356	8.0e-23	102	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644111140	419	18.54	24	417	39	447	3.0e-11	63.6	COG1538	Outer membrane protein TolC	457
644111141	117	25.45	7	114	4	108	7.0e-07	45.8	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
644111143	348	38.64	10	345	6	305	2.0e-59	222	COG2017	Galactose mutarotase or related enzyme	308
644111144	339	47.34	1	336	1	329	0.0e+00	490	COG1087	UDP-glucose 4-epimerase	329
644111145	491	50	230	486	1	257	1.0e-82	300	COG1119	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA	257
644111146	263	60.77	1	130	1	130	8.0e-40	157	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
644111148	256	46.56	10	255	14	256	2.0e-61	229	COG0725	ABC-type molybdate transport system, periplasmic component	258
644111149	229	58.41	3	228	1	225	2.0e-72	265	COG4149	ABC-type molybdate transport system, permease component	225
644111150	284	22.99	31	280	2	274	2.0e-21	96.4	COG1082	Sugar phosphate isomerase/epimerase	274
644111151	326	37.2	1	325	1	328	3.0e-75	275	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644111152	383	29.02	1	383	3	342	1.0e-52	200	COG0673	Predicted dehydrogenase	342
644111153	356	24.06	7	324	1	273	6.0e-30	125	COG1082	Sugar phosphate isomerase/epimerase	274
644111155	321	59.18	1	315	4	319	2.0e-125	442	COG0837	Glucokinase	320
644111157	61	67.21	1	61	1	61	1.0e-19	88	COG1551	sRNA-binding carbon storage regulator CsrA	73
644111158	875	59.03	1	875	4	879	0.0e+00	1215	COG0013	Alanyl-tRNA synthetase	879
644111159	164	37.2	3	164	21	166	6.0e-25	107	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
644111160	357	65.16	1	283	1	279	9.0e-88	317	COG0468	RecA/RadA recombinase	279
644111161	164	52.76	1	163	1	162	4.0e-50	190	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
644111165	224	34.68	2	223	1	203	2.0e-36	145	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
644111167	211	43.26	1	211	1	215	5.0e-56	210	COG2999	Glutaredoxin 2	215
644111170	284	59.06	3	276	42	317	8.0e-80	290	COG3207	Pyoverdine/dityrosine biosynthesis protein Dit1	330
644111173	1703	20.69	844	1580	2	660	2.0e-36	149	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
644111177	456	43.75	21	100	26	98	2.0e-11	64.6	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
644111178	678	39.78	1	545	6	550	0.0e+00	532	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
644111179	172	44.19	1	172	1	160	1.0e-49	189	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
644111181	451	24.22	152	430	41	282	1.0e-12	67.8	COG0790	TPR repeat	292
644111184	241	65	1	240	2	240	3.0e-112	397	COG1126	ABC-type polar amino acid transport system, ATPase component	240
644111185	224	40.62	2	222	1	217	1.0e-46	179	COG0765	ABC-type amino acid transport system, permease component	222
644111186	246	33.48	9	241	2	222	5.0e-48	184	COG0765	ABC-type amino acid transport system, permease component	222
644111187	298	29.08	3	278	1	275	2.0e-35	142	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644111188	509	40.04	4	509	8	514	6.0e-121	427	COG0815	Apolipoprotein N-acyltransferase	518
644111189	292	80.82	1	292	1	292	5.0e-128	450	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
644111190	159	48.37	4	153	1	153	2.0e-41	161	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
644111191	380	52.91	26	368	6	348	3.0e-122	431	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
644111192	474	51.58	1	440	1	436	0.0e+00	558	COG0621	tRNA A37 methylthiotransferase MiaB	437
644111193	388	32.65	1	387	1	384	3.0e-77	282	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
644111195	328	27.47	117	322	65	294	5.0e-21	95.7	COG4974	Site-specific recombinase XerD	300
644111205	554	37.39	1	553	1	542	0.0e+00	483	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
644111206	407	29.36	81	406	1	314	2.0e-47	183	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
644111207	381	53.16	1	377	1	376	0.0e+00	465	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
644111208	266	42.23	1	249	1	238	3.0e-65	242	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
644111209	498	35.66	1	403	3	393	7.0e-70	258	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
644111210	552	36.59	20	529	1	472	5.0e-115	408	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
644111211	149	50.35	1	143	5	144	2.0e-37	148	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
644111212	175	45.29	1	168	1	151	2.0e-33	135	COG0716	Flavodoxin	151
644111213	555	34.98	137	517	3	408	8.0e-51	195	COG0840	Methyl-accepting chemotaxis protein	408
644111216	255	24.45	4	254	9	281	3.0e-21	95.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644111218	178	71.58	1	178	1	181	1.0e-73	269	COG3057	Negative regulator of replication initiation	181
644111219	127	53.42	49	121	1	73	6.0e-13	66.6	COG0690	Preprotein translocase subunit SecE	73
644111220	181	54.86	6	180	2	176	2.0e-57	215	COG0250	Transcription antitermination factor NusG	178
644111221	142	71.63	2	142	1	140	5.0e-51	193	COG0080	Ribosomal protein L11	141
644111222	234	60.53	1	227	1	228	3.0e-81	294	COG0081	Ribosomal protein L1	228
644111223	165	46.63	1	162	1	162	3.0e-36	144	COG0244	Ribosomal protein L10	175
644111224	121	66.94	1	121	1	124	3.0e-23	100	COG0222	Ribosomal protein L7/L12	124
644111226	1407	52.61	20	853	7	808	0.0e+00	928	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
644111227	416	18.98	51	402	63	381	1.0e-05	44.8	COG2814	Predicted arabinose efflux permease, MFS family	394
644111229	478	36.79	1	469	3	457	2.0e-109	390	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644111230	373	27.47	20	368	3	359	1.0e-79	290	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
644111231	260	66.4	1	252	7	259	2.0e-104	372	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
644111233	66	34.85	1	66	3	68	1.0e-11	61.4	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
644111234	259	49	12	256	3	253	8.0e-70	256	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
644111235	213	43.15	13	209	14	207	3.0e-50	191	COG0352	Thiamine monophosphate synthase	211
644111236	651	68.7	154	611	1	432	0.0e+00	766	COG0422	Thiamine biosynthesis protein ThiC	432
644111237	153	62.5	1	152	1	152	1.0e-46	178	COG3160	Regulator of sigma D	162
644111238	260	49.25	1	258	10	275	8.0e-87	313	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
644111239	354	56.94	1	352	2	352	0.0e+00	465	COG0407	Uroporphyrinogen-III decarboxylase	352
644111240	229	51.43	5	214	7	212	3.0e-67	248	COG1515	Deoxyinosine 3'endonuclease (endonuclease V)	212
644111241	196	80.93	1	194	1	194	5.0e-89	320	COG3068	Uncharacterized protein YjaG, DUF416 family	194
644111242	90	58.89	1	90	2	91	4.0e-27	112	COG0776	Bacterial nucleoid DNA-binding protein	94
644111244	428	62.79	1	428	1	428	0.0e+00	645	COG0151	Phosphoribosylamine-glycine ligase	428
644111245	529	66.67	6	529	1	515	0.0e+00	813	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
644111247	317	32.06	6	316	11	318	2.0e-50	193	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
644111248	169	32.3	3	163	14	171	1.0e-18	86.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644111250	474	45.78	4	474	2	469	0.0e+00	469	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644111251	438	47.4	39	422	30	399	4.0e-127	448	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
644111252	514	36.29	25	483	3	467	2.0e-89	323	COG2272	Carboxylesterase type B	491
644111254	335	33.04	219	329	5	116	2.0e-16	80.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644111255	500	21.01	29	434	2	373	2.0e-11	64.5	COG2814	Predicted arabinose efflux permease, MFS family	394
644111257	486	27	206	465	1	233	1.0e-47	184	COG0775	Nucleoside phosphorylase	234
644111258	592	29.8	27	315	9	302	2.0e-34	141	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644111259	503	21.92	1	469	5	523	1.0e-46	181	COG0747	ABC-type transport system, periplasmic component	556
644111260	415	20.94	11	400	10	397	6.0e-08	52.2	COG2223	Nitrate/nitrite transporter NarK	417
644111262	257	36.73	7	239	21	264	7.0e-60	223	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
644111263	298	50.68	3	292	2	288	2.0e-58	219	COG5464	Predicted transposase YdaD	289
644111265	268	49.19	10	257	1	244	2.0e-83	302	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
644111266	569	42.45	62	305	9	253	2.0e-47	183	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
644111267	402	24.86	44	386	1	333	2.0e-29	123	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
644111268	318	24.59	9	312	1	297	3.0e-25	109	COG0583	DNA-binding transcriptional regulator, LysR family	297
644111269	251	43.03	1	251	1	251	2.0e-68	252	COG2134	CDP-diacylglycerol pyrophosphatase	252
644111273	141	52.11	1	140	1	142	9.0e-41	159	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
644111274	149	42.06	21	146	1	125	1.0e-13	69.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
644111275	474	39.14	33	473	7	448	6.0e-107	381	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
644111276	387	49.87	6	386	4	389	2.0e-126	445	COG0153	Galactokinase	390
644111277	346	54.68	8	345	1	338	1.0e-116	413	COG1085	Galactose-1-phosphate uridylyltransferase	338
644111278	297	38.44	1	293	39	332	8.0e-74	270	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644111280	435	36.36	3	435	6	429	7.0e-86	311	COG4580	Maltoporin (phage lambda and maltose receptor)	429
644111282	360	54.8	1	354	1	338	1.0e-125	443	COG3839	ABC-type sugar transport system, ATPase component	338
644111283	410	44.23	6	408	18	419	4.0e-105	375	COG2182	Maltose-binding periplasmic protein MalE	420
644111284	443	32.9	133	439	1	292	3.0e-55	209	COG1175	ABC-type sugar transport system, permease component	295
644111285	282	52.33	5	282	4	282	1.0e-89	323	COG3833	ABC-type maltose transport system, permease component	282
644111286	404	53.58	1	404	2	392	0.0e+00	514	COG3867	Arabinogalactan endo-1,4-beta-galactosidase	403
644111287	686	41.13	1	683	2	672	0.0e+00	651	COG1874	Beta-galactosidase GanA	673
644111288	113	34.12	30	112	1	85	1.0e-14	71.9	COG1264	Phosphotransferase system IIB components	88
644111289	585	18.33	21	569	1	459	1.0e-41	164	COG0277	FAD/FMN-containing dehydrogenase	459
644111290	321	45.82	6	321	2	310	5.0e-81	294	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
644111291	398	45.66	5	398	2	403	1.0e-109	390	COG1972	Nucleoside permease NupC	404
644111292	411	34.46	47	396	22	369	4.0e-30	126	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644111293	1040	39.86	13	1025	3	1009	0.0e+00	956	COG0841	Multidrug efflux pump subunit AcrB	1009
644111299	373	24.33	66	314	1	259	7.0e-19	88.6	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
644111305	335	26.32	1	335	1	336	5.0e-32	131	COG0673	Predicted dehydrogenase	342
644111306	597	33.55	1	442	4	466	1.0e-79	291	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
644111307	1204	46.01	1	536	1	539	0.0e+00	539	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
644111308	257	30	2	220	3	221	5.0e-31	128	COG1802	DNA-binding transcriptional regulator, GntR family	230
644111309	422	33.51	26	395	6	365	3.0e-71	262	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
644111310	529	44.93	233	526	6	295	9.0e-68	251	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
644111311	362	36.72	29	360	4	312	5.0e-49	188	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
644111312	290	70.2	46	290	2	246	3.0e-111	394	COG4674	ABC-type uncharacterized transport system, ATPase component	249
644111313	232	51.11	1	224	3	227	2.0e-84	305	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
644111315	274	57.6	25	274	2	240	3.0e-101	361	COG1126	ABC-type polar amino acid transport system, ATPase component	240
644111316	314	37.18	58	291	6	221	7.0e-42	164	COG0765	ABC-type amino acid transport system, permease component	222
644111318	327	27.08	77	311	34	265	3.0e-26	112	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644111319	311	26.91	66	305	34	275	6.0e-24	105	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644111322	513	28.68	19	507	35	547	2.0e-77	283	COG0747	ABC-type transport system, periplasmic component	556
644111323	616	54.26	9	572	1	539	0.0e+00	684	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
644111324	322	29.48	1	308	2	328	1.0e-35	144	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644111325	238	56.96	1	236	8	229	1.0e-78	285	COG0689	Ribonuclease PH	230
644111326	213	39.62	3	211	1	201	1.0e-50	192	COG0461	Orotate phosphoribosyltransferase	201
644111327	198	25.7	1	179	3	178	2.0e-06	45.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644111328	152	50.33	2	152	1	148	5.0e-53	200	COG0756	dUTPase	148
644111329	425	52	22	420	2	392	8.0e-121	427	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
644111330	221	50.23	3	221	6	224	1.0e-69	256	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
644111331	78	64.94	1	76	1	77	3.0e-21	93.4	COG0227	Ribosomal protein L28	77
644111332	55	62	4	53	1	50	2.0e-10	57.5	COG0267	Ribosomal protein L33	50
644111333	269	59.34	1	269	1	273	4.0e-101	361	COG0266	Formamidopyrimidine-DNA glycosylase	273
644111334	329	19.72	2	288	1	289	4.0e-18	86	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
644111335	162	61.64	1	159	1	159	2.0e-66	244	COG0669	Phosphopantetheine adenylyltransferase	159
644111336	425	57.48	2	420	1	419	0.0e+00	543	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
644111338	366	38.87	2	362	1	367	7.0e-94	337	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
644111340	256	21.05	2	254	1	263	2.0e-14	72.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
644111343	339	30.65	27	339	2	320	8.0e-65	240	COG1442	Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase	325
644111344	374	19.84	1	368	1	371	1.0e-24	107	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644111345	356	31.79	9	351	2	334	8.0e-57	214	COG0859	ADP-heptose:LPS heptosyltransferase	334
644111347	327	33.53	1	323	2	333	2.0e-67	249	COG0859	ADP-heptose:LPS heptosyltransferase	334
644111348	349	39.42	1	343	2	330	5.0e-77	281	COG0859	ADP-heptose:LPS heptosyltransferase	334
644111349	310	28.8	1	309	2	311	9.0e-47	180	COG0451	Nucleoside-diphosphate-sugar epimerase	314
644111351	291	69.07	1	291	25	315	0.0e+00	483	COG0825	Acetyl-CoA carboxylase alpha subunit	317
644111352	129	27.54	7	128	3	138	2.0e-09	54.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644111353	455	31.72	14	295	9	287	1.0e-46	181	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
644111354	84	67.86	1	84	1	84	1.0e-26	111	COG4568	Transcriptional antiterminator Rof (Rho-off)	84
644111356	184	61.67	1	180	1	180	5.0e-70	257	COG4681	Uncharacterized conserved protein YaeQ, suppresses RfaH defect	181
644111357	231	43.59	57	212	24	169	8.0e-33	134	COG3015	Uncharacterized lipoprotein NlpE involved in copper resistance	178
644111358	840	53.71	1	838	9	843	0.0e+00	1034	COG0249	DNA mismatch repair ATPase MutS	843
644111359	183	30.6	2	179	5	182	1.0e-21	96.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644111360	393	42.01	2	388	1	388	2.0e-116	412	COG1168	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	388
644111364	255	50.39	1	255	1	256	4.0e-91	327	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
644111365	319	44.68	1	319	2	330	4.0e-54	205	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
644111366	331	41.77	9	331	6	330	3.0e-52	199	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
644111367	304	49.84	1	297	5	308	1.0e-101	363	COG4594	ABC-type Fe3+-citrate transport system, periplasmic component	310
644111368	782	38.75	58	782	1	753	0.0e+00	747	COG4772	Outer membrane receptor for Fe3+-dicitrate	753
644111369	318	36.84	1	317	1	322	4.0e-67	248	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
644111370	185	27.38	12	176	4	171	7.0e-26	110	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644111371	538	30.04	15	537	6	524	3.0e-98	352	COG4943	Environmental sensor c-di-GMP phosphodiesterase, contains periplasmic CSS-motif sensor and cytoplasmic EAL domain	524
644111372	113	71.17	2	112	1	111	6.0e-46	175	COG2824	Uncharacterized Zn-ribbon-containing protein	112
644111374	361	34.53	1	356	3	339	1.0e-85	309	COG2951	Membrane-bound lytic murein transglycosylase B	343
644111376	298	29.59	3	294	1	290	1.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
644111377	235	41.67	62	234	1	180	1.0e-37	149	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644111381	250	22.83	1	250	26	301	3.0e-28	118	COG0501	Zn-dependent protease with chaperone function	302
644111383	660	68.56	10	659	5	652	0.0e+00	1025	COG1166	Arginine decarboxylase (spermidine biosynthesis)	652
644111384	383	72.09	1	383	2	388	0.0e+00	698	COG0192	S-adenosylmethionine synthetase	388
644111385	156	53.02	1	149	4	151	5.0e-46	177	COG3091	Predicted Zn-dependent metalloprotease, SprT family	156
644111386	232	70.21	1	232	1	235	8.0e-94	336	COG2356	Endonuclease I	237
644111387	244	45.97	1	242	1	246	6.0e-72	264	COG1385	16S rRNA U1498 N3-methylase RsmE	246
644111388	319	43.43	2	316	1	317	7.0e-78	284	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
644111389	187	55.32	1	187	11	194	9.0e-67	246	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
644111390	139	48.91	4	139	2	138	6.0e-44	169	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
644111391	334	66.87	1	332	1	326	0.0e+00	500	COG0158	Fructose-1,6-bisphosphatase	326
644111392	461	41.56	2	451	9	459	0.0e+00	531	COG0773	UDP-N-acetylmuramate-alanine ligase	459
644111393	432	64.65	2	430	1	429	0.0e+00	665	COG0104	Adenylosuccinate synthase	430
644111394	66	67.74	1	62	1	62	7.0e-14	69.1	COG3242	Uncharacterized conserved protein YjeT, DUF2065 family	62
644111395	331	26.51	1	325	2	288	1.0e-43	171	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
644111396	419	33.45	77	357	2	288	4.0e-52	199	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
644111397	426	54.46	8	422	3	410	0.0e+00	469	COG2262	50S ribosomal subunit-associated GTPase HflX	411
644111398	99	71.43	1	76	1	77	2.0e-26	110	COG1923	sRNA-binding regulator protein Hfq	77
644111399	313	53.09	8	311	1	305	3.0e-106	378	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
644111400	669	40.92	1	669	1	637	0.0e+00	596	COG0323	DNA mismatch repair ATPase MutL	638
644111401	556	37.6	169	410	29	231	2.0e-51	197	COG0860	N-acetylmuramoyl-L-alanine amidase	231
644111402	160	52.38	4	149	1	147	6.0e-48	183	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
644111403	522	48.25	228	506	1	284	9.0e-71	261	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
644111404	292	60.52	24	292	2	271	8.0e-99	353	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
644111405	976	36.12	253	900	7	642	3.0e-124	439	COG1020	Non-ribosomal peptide synthetase component F	642
644111408	1043	43.99	54	934	6	808	0.0e+00	686	COG3250	Beta-galactosidase/beta-glucuronidase	808
644111409	358	40.36	6	332	1	330	1.0e-73	270	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644111410	349	47.73	3	348	1	352	2.0e-118	419	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644111411	692	33.39	145	686	12	540	6.0e-93	335	COG1178	ABC-type Fe3+ transport system, permease component	540
644111412	344	43.09	45	342	2	298	1.0e-71	263	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
644111413	441	47.81	2	430	5	437	0.0e+00	463	COG2271	Sugar phosphate permease	448
644111414	524	42.5	11	519	8	496	3.0e-130	458	COG3851	Signal transduction histidine kinase, glucose-6-phosphate specific	497
644111415	209	40.76	2	208	1	211	8.0e-49	187	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644111416	270	51.84	1	270	1	268	4.0e-86	311	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
644111417	314	33.75	5	305	28	341	3.0e-42	165	COG3866	Pectate lyase	345
644111418	238	33.93	5	225	4	225	4.0e-49	188	COG1794	Aspartate/glutamate racemase	230
644111419	299	21.03	5	291	1	288	2.0e-30	126	COG0583	DNA-binding transcriptional regulator, LysR family	297
644111420	395	44.85	2	378	38	410	3.0e-85	309	COG1301	Na+/H+-dicarboxylate symporter	415
644111422	505	43.48	5	394	7	388	0.0e+00	462	COG0426	Flavorubredoxin	388
644111423	512	50.38	3	512	27	546	0.0e+00	564	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
644111424	547	42.86	38	344	1	297	6.0e-101	361	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
644111425	292	27.7	6	292	4	296	1.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
644111426	177	51.75	22	164	1	143	5.0e-47	180	COG4125	Uncharacterized membrane protein	149
644111427	220	36.27	16	207	71	273	1.0e-42	165	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
644111428	259	23.67	16	182	19	172	1.0e-14	73.3	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
644111429	371	51.37	14	196	7	187	5.0e-55	208	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
644111430	218	42.19	4	194	3	182	6.0e-42	164	COG3145	Alkylated DNA repair dioxygenase AlkB	194
644111431	509	23.72	30	505	1	413	1.0e-24	108	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
644111432	115	24.24	15	113	38	134	1.0e-05	41.6	COG3976	Uncharacterized protein, contains FMN-binding domain	135
644111433	458	20.39	1	303	9	304	2.0e-10	61	COG2814	Predicted arabinose efflux permease, MFS family	394
644111434	320	43.96	1	320	3	305	1.0e-52	200	COG3301	Formate-dependent nitrite reductase, membrane component NrfD	305
644111435	232	41.97	34	224	2	193	5.0e-50	191	COG0437	Fe-S-cluster-containing dehydrogenase component	203
644111436	300	25.68	2	294	1	290	1.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
644111437	404	31.35	9	389	23	371	2.0e-80	293	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644111438	340	33.24	1	337	1	350	1.0e-67	250	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
644111439	426	20.63	50	416	74	432	2.0e-12	67.1	COG2271	Sugar phosphate permease	448
644111440	858	57.39	5	858	1	784	0.0e+00	992	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
644111441	241	51.82	1	241	2	248	3.0e-77	281	COG1496	Copper oxidase (laccase) domain	249
644111442	325	46.86	6	303	1	289	6.0e-81	294	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644111443	244	47.54	2	243	1	234	6.0e-66	244	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
644111444	112	43.64	1	108	1	110	1.0e-27	114	COG1544	Ribosome-associated translation inhibitor RaiA	110
644111445	386	41.58	104	381	4	279	8.0e-92	330	COG0077	Prephenate dehydratase	279
644111446	373	30.63	97	353	1	279	1.0e-55	210	COG0287	Prephenate dehydrogenase	279
644111447	357	62.96	2	351	1	350	0.0e+00	563	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
644111448	238	45.9	1	238	1	244	4.0e-54	204	COG3279	DNA-binding response regulator, LytR/AlgR family	244
644111451	115	68.75	3	114	4	115	1.0e-41	161	COG0335	Ribosomal protein L19	115
644111452	251	57.44	1	241	1	240	2.0e-107	382	COG0336	tRNA G37 N-methylase TrmD	240
644111453	182	49.43	10	182	4	172	3.0e-54	204	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
644111454	82	58.54	1	82	1	81	2.0e-26	110	COG0228	Ribosomal protein S16	87
644111455	453	63.8	1	452	1	451	0.0e+00	642	COG0541	Signal recognition particle GTPase	451
644111456	264	53.99	1	262	2	262	4.0e-71	261	COG4137	ABC-type uncharacterized transport system, permease component	265
644111457	171	63.58	1	162	1	161	2.0e-69	254	COG1854	S-ribosylhomocysteine lyase LuxS, autoinducer biosynthesis	161
644111458	517	67.95	1	517	1	517	0.0e+00	760	COG2918	Gamma-glutamylcysteine synthetase	518
644111459	142	40.27	1	141	13	160	2.0e-21	94.9	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
644111460	188	38.38	4	185	1	185	9.0e-39	153	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
644111461	429	41.08	93	428	1	353	6.0e-97	348	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
644111462	458	37.5	1	230	1	225	1.0e-47	184	COG0569	Trk K+ transport system, NAD-binding component	225
644111463	137	62.96	1	133	1	130	5.0e-41	159	COG1970	Large-conductance mechanosensitive channel	130
644111464	70	57.38	2	62	3	63	1.0e-15	74.7	COG3036	Stalled ribosome alternative rescue factor ArfA	66
644111465	130	73.28	1	116	1	116	2.0e-47	180	COG0203	Ribosomal protein L17	116
644111466	329	58.81	8	323	1	313	3.0e-97	348	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
644111467	206	62.5	1	206	1	205	2.0e-59	222	COG0522	Ribosomal protein S4 or related protein	205
644111468	129	71.32	1	129	1	129	2.0e-49	187	COG0100	Ribosomal protein S11	129
644111469	118	64.71	1	118	1	119	7.0e-42	162	COG0099	Ribosomal protein S13	121
644111470	38	76.32	1	38	1	38	9.0e-06	42.1	COG0257	Ribosomal protein L36	38
644111471	443	54.44	1	434	1	432	1.0e-130	460	COG0201	Preprotein translocase subunit SecY	436
644111472	144	54	1	144	1	150	2.0e-33	134	COG0200	Ribosomal protein L15	152
644111473	59	60	5	59	1	55	9.0e-15	71.7	COG1841	Ribosomal protein L30/L7E	55
644111474	166	62.2	4	166	17	180	9.0e-59	219	COG0098	Ribosomal protein S5	181
644111475	117	51.67	1	117	6	125	9.0e-30	121	COG0256	Ribosomal protein L18	125
644111476	177	56.5	1	176	1	176	1.0e-59	222	COG0097	Ribosomal protein L6P/L9E	178
644111477	130	60.31	1	129	1	131	1.0e-46	178	COG0096	Ribosomal protein S8	132
644111478	101	63.93	41	101	1	61	2.0e-17	80.3	COG0199	Ribosomal protein S14	61
644111479	179	68.16	1	179	1	179	5.0e-81	293	COG0094	Ribosomal protein L5	180
644111480	104	53.33	1	103	1	103	7.0e-19	85.3	COG0198	Ribosomal protein L24	104
644111481	123	76.42	1	123	1	122	1.0e-49	188	COG0093	Ribosomal protein L14	122
644111482	84	53.66	1	82	4	85	2.0e-24	103	COG0186	Ribosomal protein S17	87
644111483	63	54.84	2	63	4	65	5.0e-10	56	COG0255	Ribosomal protein L29	69
644111484	136	63.24	1	133	2	137	2.0e-47	181	COG0197	Ribosomal protein L16/L10AE	146
644111485	233	63.68	12	233	1	223	2.0e-79	289	COG0092	Ribosomal protein S3	233
644111486	110	65.45	1	110	9	118	2.0e-34	137	COG0091	Ribosomal protein L22	120
644111487	92	71.74	1	92	1	92	8.0e-38	148	COG0185	Ribosomal protein S19	93
644111488	273	68.73	1	273	1	275	3.0e-113	401	COG0090	Ribosomal protein L2	275
644111489	100	61.7	7	99	1	94	9.0e-23	98.3	COG0089	Ribosomal protein L23	94
644111490	201	45.71	1	201	2	211	5.0e-55	207	COG0088	Ribosomal protein L4	214
644111491	209	62.26	1	209	1	212	9.0e-77	279	COG0087	Ribosomal protein L3	218
644111492	103	74.51	1	102	1	102	1.0e-38	151	COG0051	Ribosomal protein S10	104
644111494	157	69.43	1	157	1	157	2.0e-59	221	COG2193	Bacterioferritin (cytochrome b1)	157
644111495	64	46.88	1	64	1	63	1.0e-12	64.9	COG2906	Bacterioferritin-associated ferredoxin	63
644111497	397	35.25	3	381	2	371	2.0e-36	147	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644111498	213	22.04	1	186	2	179	5.0e-13	68.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644111500	178	50.86	1	175	1	174	9.0e-27	113	COG3923	Primosomal replication protein N''	175
644111501	131	48.74	1	118	1	119	8.0e-27	112	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
644111502	184	51.96	5	183	1	179	6.0e-50	190	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
644111503	690	41.76	1	521	1	496	0.0e+00	488	COG2812	DNA polymerase III, gamma/tau subunits	515
644111504	109	62.62	1	106	1	105	7.0e-27	112	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
644111505	201	57.29	1	199	1	198	2.0e-85	308	COG0353	Recombinational DNA repair protein RecR	198
644111506	629	65.23	3	628	1	619	0.0e+00	881	COG0326	Molecular chaperone, HSP90 family	623
644111507	214	41.74	1	214	1	178	1.0e-48	186	COG0563	Adenylate kinase or related kinase	178
644111508	320	48.6	1	318	1	316	2.0e-110	392	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
644111509	561	75.25	1	408	1	408	0.0e+00	530	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
644111510	549	35.34	11	548	5	514	3.0e-96	345	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
644111518	178	33.64	1	106	2	107	1.0e-13	69.6	COG0607	Rhodanese-related sulfurtransferase	110
644111519	466	34.23	15	461	10	449	4.0e-67	248	COG0534	Na+-driven multidrug efflux pump	455
644111520	389	33.07	1	383	1	386	3.0e-63	235	COG2807	Cyanate permease	395
644111521	171	33.67	1	171	1	199	9.0e-19	86.6	COG3637	Opacity protein and related surface antigens	199
644111522	295	59.93	1	290	1	292	3.0e-78	285	COG5006	Threonine/homoserine efflux transporter RhtA	292
644111523	183	19.13	1	179	1	178	1.0e-12	66.4	COG0563	Adenylate kinase or related kinase	178
644111524	167	36.31	14	167	1	156	9.0e-37	146	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
644111525	248	37.4	4	246	13	266	7.0e-39	154	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644111526	219	46.61	1	218	1	220	1.0e-50	193	COG0765	ABC-type amino acid transport system, permease component	222
644111527	240	64.17	1	240	2	240	2.0e-106	378	COG1126	ABC-type polar amino acid transport system, ATPase component	240
644111528	622	15.7	15	617	1	597	8.0e-27	115	COG1164	Oligoendopeptidase F	598
644111529	322	30.56	1	319	2	318	2.0e-64	239	COG0547	Anthranilate phosphoribosyltransferase	338
644111531	181	35.22	25	180	5	163	1.0e-30	126	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
644111532	398	44.27	10	382	8	391	2.0e-113	402	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
644111533	326	25.77	16	326	8	331	2.0e-35	143	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
644111534	168	25.84	1	165	1	170	2.0e-16	79.3	COG4283	Uncharacterized protein	170
644111535	206	25	1	179	2	184	9.0e-18	83.7	COG0693	Putative intracellular protease/amidase	188
644111537	338	37.72	1	332	3	333	7.0e-77	281	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644111538	486	29.6	108	469	12	386	2.0e-58	220	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
644111539	476	46.95	6	476	4	458	0.0e+00	581	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
644111540	266	35.63	6	262	3	260	1.0e-57	216	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
644111541	128	20.44	1	125	1	136	2.0e-09	54.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644111542	184	60.87	1	184	10	193	4.0e-71	260	COG3443	Periplasmic Zn/Cd-binding protein ZinT	193
644111544	407	40.58	14	383	1	323	2.0e-89	323	COG0523	GTPase, G3E family	323
644111551	300	28.43	4	300	3	291	1.0e-33	137	COG0583	DNA-binding transcriptional regulator, LysR family	297
644111557	79	71.43	3	72	5	74	1.0e-23	101	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
644111560	576	51.03	1	576	1	569	0.0e+00	616	COG4232	Thiol:disulfide interchange protein	569
644111561	110	45.63	8	110	2	104	3.0e-34	136	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
644111562	433	61.7	1	433	1	436	0.0e+00	513	COG2704	Anaerobic C4-dicarboxylate transporter	436
644111563	388	74.08	1	382	90	471	0.0e+00	662	COG1027	Aspartate ammonia-lyase	471
644111565	320	44.31	1	317	1	324	1.0e-94	339	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
644111567	187	60	1	184	1	185	7.0e-78	282	COG2818	3-methyladenine DNA glycosylase Tag	188
644111568	268	29	1	262	2	251	1.0e-10	60.8	COG0730	Uncharacterized membrane protein YfcA	258
644111569	304	81	3	302	1	298	0.0e+00	575	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
644111570	689	55.86	1	689	1	690	0.0e+00	943	COG0751	Glycyl-tRNA synthetase, beta subunit	691
644111572	635	73.62	1	467	1	470	0.0e+00	736	COG2213	Phosphotransferase system, mannitol-specific IIBC component	472
644111573	382	32.21	2	382	17	455	2.0e-89	322	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
644111574	176	64.2	1	176	2	173	9.0e-59	219	COG3722	DNA-binding transcriptional regulator, MltR family	174
644111578	1193	40.49	6	1150	5	1139	0.0e+00	851	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
644111579	621	31.63	1	612	32	692	2.0e-109	389	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
644111580	340	33.84	15	339	1	328	3.0e-72	265	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644111581	398	38.57	42	393	11	371	1.0e-72	267	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644111582	441	41.48	23	290	1	264	2.0e-78	286	COG0548	Acetylglutamate kinase	265
644111583	378	35.27	135	375	25	231	4.0e-52	199	COG0860	N-acetylmuramoyl-L-alanine amidase	231
644111587	370	50.68	2	355	10	370	2.0e-117	415	COG2821	Membrane-bound lytic murein transglycosylase	373
644111590	212	54	2	201	1	200	2.0e-81	295	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
644111591	345	67.87	4	334	1	333	0.0e+00	525	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
644111592	208	65.55	1	208	2	210	5.0e-80	290	COG0035	Uracil phosphoribosyltransferase	210
644111593	429	39.78	6	424	7	451	1.0e-83	304	COG2233	Xanthine/uracil permease	451
644111595	125	41.38	10	125	3	117	6.0e-34	136	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
644111596	478	51.37	4	477	13	484	0.0e+00	489	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
644111597	155	52.29	1	153	1	153	3.0e-56	210	COG1225	Peroxiredoxin	157
644111598	183	55.68	5	180	1	176	4.0e-58	217	COG2716	Glycine cleavage system regulatory protein	176
644111599	292	50.68	1	292	4	297	4.0e-94	338	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
644111600	345	53.94	6	344	1	342	5.0e-99	354	COG3317	Uncharacterized lipoprotein	342
644111601	237	53.97	1	237	1	239	3.0e-82	298	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
644111602	150	60.96	4	149	2	147	4.0e-36	143	COG2707	Uncharacterized membrane protein, DUF441 family	151
644111604	383	23.3	61	357	3	304	8.0e-14	71.9	COG0582	Integrase	309
644111606	71	30.77	1	65	6	69	6.0e-07	45.7	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
644111609	868	34.82	346	868	39	562	3.0e-108	386	COG5519	Uncharcterized protein, DUF927 family	562
644111612	81	46.97	1	66	2	67	5.0e-12	62.7	COG3905	Predicted transcriptional regulator	83
644111613	94	32.29	1	94	2	96	2.0e-10	57.8	COG3668	Plasmid stabilization system protein ParE	98
644111616	435	25.21	1	332	2	343	1.0e-29	124	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
644111618	301	35.4	5	290	6	289	7.0e-46	177	COG2971	BadF-type ATPase, related to human N-acetylglucosamine kinase	301
644111620	236	41.33	1	220	4	228	6.0e-61	227	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
644111621	284	44.2	7	281	4	274	1.0e-34	140	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
644111622	292	36.9	5	292	14	302	2.0e-66	246	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
644111624	271	40.73	25	271	6	252	3.0e-59	222	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
644111625	326	49.24	1	326	2	326	3.0e-103	368	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
644111626	442	30.96	13	437	5	413	2.0e-56	213	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
644111631	322	33.33	200	319	1	120	7.0e-20	91.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644111632	612	33.63	26	589	8	567	7.0e-109	388	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
644111633	590	31.58	38	587	18	567	2.0e-97	350	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
644111634	245	41.54	176	240	1	65	1.0e-10	60.8	COG2771	DNA-binding transcriptional regulator, CsgD family	65
644111635	204	22.5	4	203	9	201	2.0e-07	49.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644111636	214	26.7	7	194	4	184	4.0e-19	88.1	COG3009	Uncharacterized lipoprotein YmbA	190
644111637	548	35.73	4	526	6	539	4.0e-111	395	COG3008	Paraquat-inducible protein B	553
644111639	2707	44.23	273	932	1	642	0.0e+00	530	COG1020	Non-ribosomal peptide synthetase component F	642
644111640	1138	39.79	294	941	1	642	2.0e-125	444	COG1020	Non-ribosomal peptide synthetase component F	642
644111642	183	33.06	40	162	19	142	2.0e-17	82.3	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
644111643	103	34.34	1	99	1	98	1.0e-19	88.1	COG4680	mRNA-degrading endonuclease (mRNA interferase) HigB, toxic component of the HigAB toxin-antitoxin module	98
644111644	138	35.77	16	138	1	120	2.0e-24	105	COG5499	Antitoxin component HigA of the HigAB toxin-antitoxin module, contains an N-terminal HTH domain	120
644111646	450	27.49	33	433	23	436	2.0e-48	186	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
644111647	423	25.85	24	406	5	382	2.0e-20	93.7	COG2814	Predicted arabinose efflux permease, MFS family	394
644111648	148	38.66	2	119	1	119	3.0e-25	107	COG1733	DNA-binding transcriptional regulator, HxlR family	120
644111650	217	24.54	2	216	1	213	3.0e-19	88.4	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
644111651	154	36.14	1	154	2	167	1.0e-32	132	COG0602	Organic radical activating enzyme	212
644111652	712	44.41	1	706	1	699	0.0e+00	888	COG1328	Anaerobic ribonucleoside-triphosphate reductase	700
644111653	245	56.43	1	241	1	240	4.0e-88	317	COG3484	Predicted proteasome-type protease	255
644111656	331	26.88	12	289	1	275	6.0e-29	121	COG0583	DNA-binding transcriptional regulator, LysR family	297
644111657	505	31.94	33	223	10	186	2.0e-21	97.2	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
644111661	105	30.59	5	89	6	90	2.0e-11	60.8	COG5606	Predicted DNA-binding protein, XRE-type HTH domain	91
644111664	525	62.55	1	523	1	526	0.0e+00	737	COG4650	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain	531
644111665	382	33.99	16	382	4	401	1.0e-112	399	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
644111666	288	47.97	1	288	1	281	1.0e-72	266	COG0682	Prolipoprotein diacylglyceryltransferase	287
644111667	264	69.17	1	264	3	268	5.0e-121	426	COG0207	Thymidylate synthase	268
644111671	169	30	2	169	26	194	2.0e-17	82.3	COG4795	Type II secretory pathway, component PulJ	194
644111675	1042	50.67	1	1037	91	1072	0.0e+00	1042	COG1330	Exonuclease V gamma subunit	1078
644111676	900	52.11	26	899	5	878	0.0e+00	982	COG1025	Secreted/periplasmic Zn-dependent peptidases, insulinase-like	937
644111677	353	23.41	15	353	2	330	8.0e-26	111	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
644111678	396	25.91	69	395	1	328	1.0e-56	214	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644111679	147	30.46	1	147	1	149	3.0e-26	111	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
644111680	95	31.18	1	91	2	93	1.0e-10	58.3	COG3414	Phosphotransferase system, galactitol-specific IIB component	93
644111681	419	50.57	1	419	5	441	1.0e-113	403	COG3037	Ascorbate-specific PTS system EIIC-type component UlaA	481
644111682	221	32.89	1	216	8	235	3.0e-49	188	COG0176	Transaldolase	239
644111683	119	62.71	1	117	1	118	3.0e-38	150	COG3112	Uncharacterized protein YacL, UPF0231 family	121
644111684	865	85.37	1	861	1	852	0.0e+00	1554	COG1049	Aconitase B	852
644111687	266	35.96	1	266	1	256	6.0e-56	211	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
644111690	332	43.84	1	330	1	346	2.0e-102	366	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
644111691	416	46.96	6	416	8	370	6.0e-121	427	COG5276	Uncharacterized conserved protein	370
644111692	358	23.55	1	305	4	297	2.0e-20	93.3	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
644111693	211	54.46	1	211	1	212	2.0e-58	218	COG2864	Cytochrome b subunit of formate dehydrogenase	218
644111694	302	42.66	21	238	2	202	2.0e-58	219	COG0437	Fe-S-cluster-containing dehydrogenase component	203
644111697	269	32.19	35	173	3	144	7.0e-14	71.2	COG4675	Microcystin-dependent protein  (function unknown)	170
644111701	309	22.76	1	122	1	123	2.0e-07	50.3	COG3499	Phage protein U	147
644111703	386	30.75	15	354	1	346	2.0e-61	229	COG3500	Phage protein D	350
644111704	193	40.76	5	186	6	184	7.0e-34	137	COG4540	Phage P2 baseplate assembly protein gpV	184
644111705	115	32.43	8	115	5	115	2.0e-24	103	COG3628	Phage baseplate assembly protein W	116
644111706	367	32.63	35	365	1	305	3.0e-62	232	COG3948	Phage-related baseplate assembly protein	306
644111708	193	24.59	3	182	2	164	3.0e-19	88.5	COG4385	Bacteriophage P2-related tail formation protein	206
644111712	294	37.76	1	292	1	290	7.0e-69	254	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
644111713	316	41.07	9	315	7	323	7.0e-79	287	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
644111714	424	19.72	1	413	34	448	2.0e-31	130	COG2271	Sugar phosphate permease	448
644111715	457	17.73	1	413	8	447	9.0e-22	98.4	COG0591	Na+/proline symporter	493
644111716	395	38.35	1	394	1	378	2.0e-60	226	COG4692	Predicted neuraminidase (sialidase)	381
644111717	155	31.65	1	155	1	154	9.0e-24	103	COG2731	Beta-galactosidase, beta subunit	154
644111718	229	34.29	7	226	6	249	3.0e-29	121	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644111719	2738	38.95	1368	2021	1	642	2.0e-122	435	COG1020	Non-ribosomal peptide synthetase component F	642
644111721	437	59.17	1	435	1	433	0.0e+00	478	COG2851	Mg2+/citrate symporter	433
644111724	487	36.68	120	443	60	408	3.0e-48	186	COG0840	Methyl-accepting chemotaxis protein	408
644111728	296	21.25	8	292	14	257	4.0e-22	98.5	COG3504	Type IV secretory pathway, VirB9 components	265
644111729	227	31.65	8	223	22	232	4.0e-31	128	COG3736	Type IV secretory pathway, component VirB8	239
644111731	346	18.46	32	337	72	387	8.0e-07	48.5	COG3704	Type IV secretory pathway, VirB6 components	406
644111735	182	46.37	4	182	2	173	7.0e-54	203	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
644111737	275	42.34	7	273	9	281	6.0e-75	274	COG0169	Shikimate 5-dehydrogenase	283
644111738	189	38.54	2	189	9	197	1.0e-50	192	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
644111739	185	37.04	50	177	1	135	2.0e-22	99.1	COG0551	ssDNA-binding Zn-finger and Zn-ribbon domains of topoisomerase 1	140
644111740	157	73.25	1	157	1	157	1.0e-57	215	COG2922	Uncharacterized conserved protein Smg, DUF494 family	157
644111741	364	44.58	21	352	35	350	3.0e-92	332	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
644111742	170	55.36	1	164	1	168	1.0e-55	209	COG0242	Peptide deformylase	168
644111743	315	53.64	4	305	1	302	3.0e-118	418	COG0223	Methionyl-tRNA formyltransferase	307
644111747	488	23.47	18	488	14	455	6.0e-32	132	COG1538	Outer membrane protein TolC	457
644111751	512	42.31	176	512	121	457	4.0e-92	332	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644111752	790	40.63	8	789	70	784	0.0e+00	710	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
644111755	527	38.08	29	503	1	429	2.0e-111	396	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
644111756	253	55.16	4	252	6	250	6.0e-82	297	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
644111758	345	35.74	6	337	7	291	2.0e-80	292	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
644111759	319	43.1	84	319	1	238	3.0e-60	225	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
644111760	316	61.54	10	295	4	283	2.0e-108	386	COG1072	Panthothenate kinase	283
644111767	1611	37.27	346	995	1	641	3.0e-119	423	COG1020	Non-ribosomal peptide synthetase component F	642
644111768	1541	39.16	237	883	1	641	1.0e-125	445	COG1020	Non-ribosomal peptide synthetase component F	642
644111770	520	70.58	1	520	1	519	0.0e+00	829	COG3634	Alkyl hydroperoxide reductase subunit AhpF	520
644111771	187	49.47	1	184	2	188	2.0e-63	235	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
644111774	78	45	1	78	1	80	1.0e-12	65.1	COG5302	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid	80
644111787	212	27.5	1	160	1	151	7.0e-33	133	COG0698	Ribose 5-phosphate isomerase RpiB	151
644111788	677	43.93	5	562	2	537	0.0e+00	584	COG1292	Choline-glycine betaine transporter	537
644111789	195	21.51	1	171	4	174	3.0e-11	62	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644111791	728	21.33	25	723	27	756	2.0e-40	161	COG4694	Wobble nucleotide-excising tRNase	758
644111793	206	49.76	1	205	1	205	2.0e-64	238	COG3103	Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family	205
644111794	414	36.52	1	391	23	405	2.0e-84	306	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
644111795	272	56.62	2	272	1	268	6.0e-72	264	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
644111796	117	46.61	1	117	2	119	7.0e-34	135	COG1539	Dihydroneopterin aldolase	121
644111797	211	51.5	1	193	1	200	3.0e-59	221	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
644111799	617	42.41	1	544	6	550	0.0e+00	559	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
644111800	135	35.04	1	131	3	139	2.0e-25	108	COG5435	Uncharacterized protein	147
644111801	474	41.89	130	202	25	97	3.0e-08	53.8	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
644111803	473	19.95	37	456	46	444	2.0e-31	130	COG1538	Outer membrane protein TolC	457
644111804	429	73.52	1	423	50	471	0.0e+00	717	COG1027	Aspartate ammonia-lyase	471
644111806	78	45	1	78	1	80	1.0e-12	64.3	COG5302	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid	80
644111809	286	47.46	7	279	12	287	7.0e-56	210	COG5006	Threonine/homoserine efflux transporter RhtA	292
644111810	164	33.12	6	159	2	154	2.0e-23	102	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644111812	451	23.84	3	451	38	438	4.0e-51	196	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
644111833	187	54.79	1	187	1	180	1.0e-60	225	COG0241	Histidinol phosphatase or a related phosphatase	181
644111843	90	72.97	11	84	7	80	2.0e-23	100	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
644111847	90	69.62	6	84	2	80	8.0e-24	102	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
644111848	98	73.47	1	98	1	98	7.0e-31	125	COG3691	Uncharacterized conserved protein YfcZ, UPF0381/DUF406 family	98
644111851	316	37.46	4	314	1	239	3.0e-67	249	COG0176	Transaldolase	239
644111854	406	38.78	1	406	66	473	2.0e-101	363	COG1953	Cytosine/uracil/thiamine/allantoin permease	497
