gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
647803263	306	28.48	3	298	2	295	2.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
647803264	257	30.59	5	255	2	251	2.0e-32	132	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647803265	211	29.35	36	209	4	182	2.0e-14	72.7	COG3803	Uncharacterized conserved protein, DUF924 family	182
647803266	390	33.33	20	388	15	380	4.0e-53	202	COG4292	Low temperature requirement protein LtrA (function unknown)	387
647803271	466	44.06	3	462	1	461	0.0e+00	488	COG1904	Glucuronate isomerase	463
647803273	784	32.25	31	730	34	711	0.0e+00	550	COG1501	Alpha-glucosidase, glycosyl hydrolase family GH31	772
647803274	433	53.3	51	429	1	378	7.0e-94	337	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647803275	171	31.9	4	166	11	170	3.0e-18	85	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647803277	324	34.15	2	324	6	330	8.0e-75	274	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647803279	243	39.57	5	225	10	236	1.0e-42	166	COG2186	DNA-binding transcriptional regulator, FadR family	241
647803280	389	54.97	1	382	1	355	0.0e+00	462	COG1312	D-mannonate dehydratase	362
647803281	244	48.5	12	240	21	253	2.0e-73	268	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
647803282	317	45.49	32	314	43	330	3.0e-51	195	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
647803283	336	23.37	1	330	7	312	3.0e-27	116	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
647803293	312	35.02	18	292	6	276	2.0e-61	229	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
647803295	513	39.13	305	509	1	207	3.0e-47	183	COG0400	Predicted esterase	207
647803296	104	37.78	7	95	8	96	2.0e-18	84.2	COG2388	Predicted acetyltransferase, GNAT superfamily	99
647803297	179	39.13	2	179	1	179	1.0e-32	132	COG0431	NAD(P)H-dependent FMN reductase	184
647803299	396	23.71	23	395	20	386	6.0e-23	102	COG4292	Low temperature requirement protein LtrA (function unknown)	387
647803301	317	33.89	18	314	2	297	8.0e-38	150	COG0583	DNA-binding transcriptional regulator, LysR family	297
647803306	271	22.03	30	257	4	221	9.0e-09	54.2	COG2801	Transposase InsO and inactivated derivatives	232
647803309	157	27.92	1	153	2	149	6.0e-23	100	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
647803310	124	34.31	10	109	8	109	8.0e-10	56	COG0640	DNA-binding transcriptional regulator, ArsR family	110
647803319	117	18.58	9	114	14	124	5.0e-07	46.4	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
647803324	144	52.9	1	136	1	138	8.0e-51	192	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
647803325	241	54.31	1	115	1	116	1.0e-31	130	COG5507	Uncharacterized  conserved protein YbaA, DUF1428 family	117
647803326	218	35	7	101	2	101	2.0e-18	86.2	COG1733	DNA-binding transcriptional regulator, HxlR family	120
647803329	148	22.6	3	142	5	149	2.0e-12	65.1	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
647803330	118	34.51	4	115	2	110	6.0e-19	86.2	COG3791	Uncharacterized conserved protein	133
647803335	387	28.73	106	378	1	259	1.0e-43	171	COG1192	Cellulose biosynthesis protein BcsQ	259
647803336	333	25.1	45	280	1	230	1.0e-18	87.7	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
647803343	311	29.65	1	311	10	322	1.0e-39	157	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
647803344	334	42.27	13	328	2	307	9.0e-47	181	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
647803345	501	50.4	1	491	4	499	0.0e+00	558	COG1129	ABC-type sugar transport system, ATPase component	500
647803346	380	27.35	11	370	3	334	1.0e-44	173	COG0673	Predicted dehydrogenase	342
647803347	370	25.23	25	343	1	274	5.0e-31	128	COG1082	Sugar phosphate isomerase/epimerase	274
647803348	352	45.07	24	352	1	333	1.0e-76	279	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
647803355	456	39.2	109	435	57	408	7.0e-41	162	COG0840	Methyl-accepting chemotaxis protein	408
647803359	239	25.74	5	238	84	301	2.0e-13	69.9	COG3547	Transposase	303
647803371	692	24.15	227	690	31	499	5.0e-06	46.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
647803374	271	22.03	30	257	4	221	9.0e-09	54.2	COG2801	Transposase InsO and inactivated derivatives	232
647803375	336	30.98	4	325	1	301	2.0e-34	140	COG3547	Transposase	303
647803381	137	21.77	21	137	2	118	2.0e-07	48.6	COG3293	Transposase	124
647803382	129	30.16	3	128	1	122	7.0e-10	56.3	COG3293	Transposase	124
647803383	96	41.24	1	96	1	97	2.0e-23	100	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
647803384	97	37.23	5	97	1	94	2.0e-21	94.2	COG3549	Plasmid maintenance system killer protein	94
647803397	159	45.99	20	155	18	153	1.0e-25	109	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
647803398	441	20.92	46	394	49	382	3.0e-11	63.7	COG2814	Predicted arabinose efflux permease, MFS family	394
647803399	86	31.82	4	86	2	89	9.0e-13	65.2	COG1937	DNA-binding transcriptional regulator, FrmR family	89
647803404	272	62.41	122	262	3	143	2.0e-51	196	COG4275	Uncharacterized protein	143
647803405	430	38.92	10	192	2	186	2.0e-31	130	COG2059	Chromate transport protein ChrA	195
647803423	225	19.92	1	222	2	257	3.0e-15	75.2	COG1192	Cellulose biosynthesis protein BcsQ	259
647803426	271	22.03	30	257	4	221	9.0e-09	54.2	COG2801	Transposase InsO and inactivated derivatives	232
647803435	141	30.71	2	134	9	148	3.0e-13	68	COG1525	Endonuclease YncB, thermonuclease family	192
647803437	139	33.58	1	137	3	129	5.0e-18	83.7	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
647803444	758	18.03	92	525	62	528	2.0e-35	144	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
647803450	263	39.83	13	244	13	247	7.0e-43	167	COG1484	DNA replication protein DnaC	254
647803451	526	27.94	22	289	7	257	5.0e-19	89.7	COG4584	Transposase	278
647803456	265	24.15	1	265	1	262	4.0e-28	118	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
647803457	427	29.41	73	427	22	371	6.0e-55	208	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
647803458	217	33.48	1	216	24	243	5.0e-55	207	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
647803460	542	33.55	121	272	11	157	3.0e-22	100	COG3436	Transposase	157
647803470	402	29.54	1	234	2	227	2.0e-25	110	COG1216	Glycosyltransferase, GT2 family	305
647803477	479	44.71	3	340	2	333	3.0e-97	349	COG0836	Mannose-1-phosphate guanylyltransferase	333
647803478	388	40.14	1	388	1	414	2.0e-118	419	COG1004	UDP-glucose 6-dehydrogenase	414
647803479	292	53.68	4	288	1	282	1.0e-110	392	COG1209	dTDP-glucose pyrophosphorylase	286
647803480	290	48.07	10	289	1	281	2.0e-79	289	COG1091	dTDP-4-dehydrorhamnose reductase	281
647803483	402	28.95	11	367	2	365	2.0e-25	110	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
647803484	182	50.85	1	175	1	173	4.0e-54	204	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
647803486	415	16.62	1	390	1	363	6.0e-16	78.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647803487	312	33.13	8	310	1	312	9.0e-44	170	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647803488	372	69.38	1	356	2	345	0.0e+00	577	COG1089	GDP-D-mannose dehydratase	345
647803491	411	46.75	15	404	7	404	4.0e-89	321	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
647803492	119	42.86	1	119	1	119	2.0e-25	107	COG3795	Uncharacterized conserved protein	123
647803495	323	54.59	17	210	7	202	6.0e-56	211	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
647803499	220	27.89	22	207	32	200	2.0e-19	89.6	COG5620	Uncharacterized protein	200
647803503	345	29.57	4	338	3	311	1.0e-48	187	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647803509	312	20.06	4	312	1	286	2.0e-06	46.7	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
647803510	204	30.35	5	202	41	222	8.0e-33	133	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
647803511	290	20.08	13	233	4	254	5.0e-11	62.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647803512	370	23	83	280	48	239	5.0e-17	82.5	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
647803520	632	40.69	16	622	1	578	0.0e+00	505	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
647803526	466	36.33	44	305	73	324	2.0e-37	150	COG0642	Signal transduction histidine kinase	336
647803527	603	36.46	418	594	1	179	1.0e-30	128	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
647803532	724	47.28	347	714	5	355	7.0e-105	375	COG4362	Nitric oxide synthase, oxygenase domain	355
647803533	263	39.83	13	244	13	247	7.0e-43	167	COG1484	DNA replication protein DnaC	254
647803534	526	27.94	22	289	7	257	5.0e-19	89.7	COG4584	Transposase	278
647803536	117	34.51	2	112	1	113	6.0e-13	66.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
647803542	285	43.61	18	280	1	263	3.0e-70	258	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
647803543	162	32.28	1	158	2	156	1.0e-32	132	COG0835	Chemotaxis signal transduction protein	165
647803544	711	35.69	4	693	8	709	0.0e+00	559	COG0643	Chemotaxis protein histidine kinase CheA	716
647803548	785	40.35	414	730	67	408	1.0e-54	208	COG0840	Methyl-accepting chemotaxis protein	408
647803550	187	43.71	3	164	2	162	4.0e-41	160	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
647803552	523	33.08	1	519	1	528	2.0e-102	366	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
647803553	268	37.27	5	268	11	281	4.0e-47	181	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
647803554	291	39.38	1	291	3	294	8.0e-54	203	COG1175	ABC-type sugar transport system, permease component	295
647803555	425	30.48	1	424	7	433	3.0e-40	159	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
647803556	356	49.85	9	335	3	336	3.0e-112	398	COG3839	ABC-type sugar transport system, ATPase component	338
647803558	355	33.22	10	295	2	266	2.0e-61	229	COG1018	Ferredoxin-NADP reductase	266
647803559	408	36.27	18	398	5	358	3.0e-75	275	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
647803561	318	22.71	2	313	6	332	7.0e-21	95	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647803564	466	31.33	70	466	5	379	3.0e-53	203	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647803570	255	34.05	18	247	10	230	4.0e-36	145	COG1183	Phosphatidylserine synthase	234
647803571	233	46.01	8	217	25	236	4.0e-56	211	COG0688	Phosphatidylserine decarboxylase	239
647803574	163	25.2	36	162	1	125	3.0e-07	48	COG1846	DNA-binding transcriptional regulator, MarR family	126
647803575	706	18.67	41	706	8	768	7.0e-20	93.1	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647803577	349	59.46	8	337	1	311	5.0e-114	404	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
647803578	909	58.06	1	866	8	842	0.0e+00	1156	COG1410	Methionine synthase I, cobalamin-binding domain	842
647803579	160	39.02	37	159	15	137	1.0e-18	85.7	COG3011	Predicted thiol-disulfide oxidoreductase YuxK, DCC family	137
647803581	506	45.9	19	501	1	472	0.0e+00	496	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647803585	798	38.67	159	797	13	650	0.0e+00	561	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
647803586	307	27.21	19	306	2	294	1.0e-28	120	COG0583	DNA-binding transcriptional regulator, LysR family	297
647803589	176	30.77	4	155	3	155	2.0e-18	85.8	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
647803592	268	36.15	10	262	35	294	2.0e-40	159	COG0668	Small-conductance mechanosensitive channel	316
647803594	374	65.41	1	370	1	370	0.0e+00	525	COG0686	Alanine dehydrogenase	371
647803595	153	42.76	1	152	4	154	4.0e-34	137	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647803596	305	60.84	17	275	8	270	2.0e-100	358	COG2326	Polyphosphate kinase 2, PPK2 family	270
647803597	223	35.62	1	158	10	164	2.0e-18	86.2	COG0558	Phosphatidylglycerophosphate synthase	192
647803598	81	41.98	3	81	4	84	1.0e-12	65	COG1977	Molybdopterin converting factor, small subunit	84
647803599	148	45.95	1	147	4	149	5.0e-35	140	COG0314	Molybdopterin synthase catalytic subunit	149
647803602	638	29.17	457	600	45	188	2.0e-22	101	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
647803603	320	35.37	26	319	7	289	8.0e-44	171	COG0382	4-hydroxybenzoate polyprenyltransferase	289
647803604	246	35.48	6	245	5	246	8.0e-53	200	COG1385	16S rRNA U1498 N3-methylase RsmE	246
647803607	456	53.11	10	456	10	456	0.0e+00	544	COG3572	Gamma-glutamylcysteine synthetase	456
647803611	202	49.74	17	200	10	200	2.0e-41	161	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
647803612	436	39.59	1	435	1	423	1.0e-98	353	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
647803614	319	46.95	5	306	4	310	2.0e-99	356	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
647803616	219	49.46	36	219	11	194	1.0e-59	223	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
647803618	1137	25.51	11	1031	1	1005	4.0e-127	450	COG0841	Multidrug efflux pump subunit AcrB	1009
647803619	487	28.94	82	349	58	314	7.0e-20	92.3	COG1566	Multidrug resistance efflux pump	352
647803620	180	45.78	10	173	5	169	1.0e-48	186	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
647803621	207	43.14	4	203	3	205	7.0e-23	100	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
647803622	199	31.07	1	190	4	203	8.0e-18	83.8	COG2129	Predicted phosphoesterase, related to the Icc protein	226
647803623	255	42.78	72	252	7	200	7.0e-40	157	COG1573	Uracil-DNA glycosylase	202
647803624	319	47.83	6	212	4	209	1.0e-58	220	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
647803626	570	33.57	35	444	7	386	2.0e-63	237	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647803627	347	19.62	28	292	11	242	7.0e-19	88.4	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647803630	480	41.98	75	473	13	413	3.0e-75	276	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
647803631	144	43.36	28	139	9	121	2.0e-23	101	COG1321	Mn-dependent transcriptional regulator, DtxR family	154
647803634	114	28.43	13	113	6	107	1.0e-05	42.1	COG4392	Branched-chain amino acid transport protein	107
647803635	242	30.84	1	225	3	225	2.0e-30	125	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
647803636	293	31.35	28	272	16	265	7.0e-48	184	COG1526	Formate dehydrogenase assembly factor FdhD	266
647803638	212	40.28	1	211	2	192	1.0e-38	153	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
647803639	163	44.72	1	157	2	159	3.0e-36	144	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
647803641	419	45.61	22	416	7	404	4.0e-96	345	COG0303	Molybdopterin biosynthesis enzyme	404
647803642	170	25.33	1	149	12	154	1.0e-10	59.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
647803644	156	53.33	6	155	1	150	1.0e-40	158	COG0782	Transcription elongation factor, GreA/GreB family	151
647803647	151	34.17	7	121	1	120	3.0e-18	84.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
647803648	549	32.46	9	463	2	396	2.0e-74	273	COG0644	Dehydrogenase (flavoprotein)	396
647803649	572	23.53	301	521	43	222	1.0e-09	58.5	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
647803650	274	40.21	1	274	1	284	2.0e-63	235	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
647803651	336	37.42	17	336	3	322	5.0e-77	281	COG0142	Geranylgeranyl pyrophosphate synthase	322
647803653	262	31.6	9	236	5	235	4.0e-40	158	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
647803656	312	28.09	6	298	1	295	2.0e-30	126	COG0583	DNA-binding transcriptional regulator, LysR family	297
647803658	240	41.13	3	237	6	250	7.0e-44	170	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647803659	391	47.77	1	391	1	392	2.0e-86	313	COG0183	Acetyl-CoA acetyltransferase	392
647803661	279	31.38	28	263	2	239	8.0e-44	170	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
647803663	187	39.67	46	165	10	127	3.0e-11	61.8	COG0526	Thiol-disulfide isomerase or thioredoxin	127
647803664	463	57.86	6	463	2	458	0.0e+00	634	COG0165	Argininosuccinate lyase	459
647803667	421	46.73	1	394	1	394	5.0e-116	411	COG0019	Diaminopimelate decarboxylase	394
647803672	225	46.36	1	219	1	216	2.0e-65	242	COG2884	ABC-type ATPase involved in cell division	223
647803673	297	25.18	18	291	17	293	2.0e-24	106	COG2177	Cell division protein FtsX	297
647803674	249	27.02	8	248	1	240	3.0e-23	102	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
647803675	204	31.14	4	162	1	163	6.0e-24	104	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
647803678	465	50.54	1	455	2	454	0.0e+00	498	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
647803680	136	28.03	5	136	1	125	8.0e-10	56.4	COG3686	Uncharacterized conserved protein, MAPEG superfamily	125
647803682	501	52.08	103	500	1	404	3.0e-108	386	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
647803683	984	53.57	7	984	1	906	0.0e+00	1273	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
647803685	295	65.65	1	294	1	291	1.0e-118	419	COG0074	Succinyl-CoA synthetase, alpha subunit	293
647803686	279	22.75	5	205	5	211	4.0e-21	95.4	COG3306	Glycosyltransferase involved in LPS biosynthesis, GR25 family	255
647803687	397	59.4	1	397	1	386	0.0e+00	524	COG0045	Succinyl-CoA synthetase, beta subunit	387
647803689	320	44.3	4	318	1	313	3.0e-102	364	COG0039	Malate/lactate dehydrogenase	313
647803693	284	42.7	10	281	1	280	2.0e-56	213	COG2301	Citrate lyase beta subunit	283
647803695	67	62.12	1	65	3	68	6.0e-21	92.4	COG5515	Uncharacterized protein	70
647803696	376	29.75	1	152	8	156	2.0e-13	70.1	COG2030	Acyl dehydratase	159
647803697	191	23.08	1	171	2	183	5.0e-15	74.5	COG0406	Broad specificity phosphatase PhoE	208
647803698	127	39.02	9	127	3	125	1.0e-13	68.8	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
647803699	123	26.09	9	122	3	117	4.0e-10	57.1	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
647803700	602	53.71	8	579	3	561	0.0e+00	623	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
647803703	259	51.93	26	257	1	230	3.0e-84	304	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
647803708	505	34.23	1	484	1	510	9.0e-99	354	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
647803709	405	32.72	43	405	24	394	2.0e-74	273	COG0019	Diaminopimelate decarboxylase	394
647803710	285	36.56	1	277	3	263	3.0e-58	218	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
647803711	234	52.59	1	232	2	233	2.0e-89	321	COG0813	Purine-nucleoside phosphorylase	236
647803712	106	32.11	5	106	20	127	6.0e-08	49.2	COG2916	DNA-binding protein H-NS	128
647803713	661	45.1	14	499	69	548	0.0e+00	492	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
647803716	426	29.06	37	410	1	326	3.0e-50	192	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647803719	245	35.15	3	237	7	242	1.0e-38	153	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647803721	305	30.36	12	291	5	257	2.0e-16	79.7	COG0730	Uncharacterized membrane protein YfcA	258
647803722	335	46.57	1	335	2	304	2.0e-74	273	COG1079	ABC-type uncharacterized transport system, permease component	304
647803723	364	41.24	3	355	7	350	1.0e-69	257	COG4603	ABC-type uncharacterized transport system, permease component	356
647803724	509	54.38	4	503	3	501	0.0e+00	646	COG3845	ABC-type uncharacterized transport system, ATPase component	501
647803725	331	43.88	2	327	14	344	1.0e-74	273	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
647803726	145	28.29	13	145	26	177	5.0e-16	77	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
647803727	215	33.03	7	205	2	219	8.0e-32	130	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
647803729	187	53.16	109	185	6	84	2.0e-24	105	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
647803733	225	45.58	1	215	9	211	2.0e-72	265	COG0321	Lipoate-protein ligase B	221
647803734	360	52.46	1	345	1	338	2.0e-117	415	COG3839	ABC-type sugar transport system, ATPase component	338
647803735	310	29.49	6	310	1	305	2.0e-33	136	COG0524	Sugar or nucleoside kinase, ribokinase family	311
647803736	340	24.56	17	339	7	337	9.0e-40	157	COG2222	Fructoselysine-6-P-deglycase FrlB and related proteins with duplicated sugar isomerase (SIS) domain	340
647803737	281	35.48	6	280	8	281	2.0e-49	189	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
647803738	294	39.72	8	294	10	295	3.0e-59	222	COG1175	ABC-type sugar transport system, permease component	295
647803739	409	26.19	1	406	8	425	1.0e-42	167	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
647803740	396	22.19	88	379	1	297	1.0e-26	114	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
647803741	308	27.81	1	307	1	300	1.0e-34	140	COG0524	Sugar or nucleoside kinase, ribokinase family	311
647803747	393	38.54	5	386	10	389	3.0e-90	325	COG1686	D-alanyl-D-alanine carboxypeptidase	389
647803748	214	41.55	8	213	3	208	8.0e-54	203	COG0125	Thymidylate kinase	208
647803750	267	47.08	5	259	2	256	2.0e-76	279	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
647803751	265	31.48	3	261	3	261	8.0e-40	157	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
647803752	310	31.19	1	310	1	308	7.0e-33	134	COG0679	Predicted permease	311
647803753	181	54.39	4	173	6	165	7.0e-62	230	COG0678	Peroxiredoxin	165
647803754	463	23.27	17	458	13	409	4.0e-30	126	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647803755	521	31.79	4	517	1	536	4.0e-83	302	COG0405	Gamma-glutamyltranspeptidase	539
647803756	327	48.33	1	300	1	258	6.0e-96	344	COG4608	ABC-type oligopeptide transport system, ATPase component	309
647803757	331	56.07	5	321	1	316	1.0e-118	419	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
647803758	298	51.06	16	298	9	288	1.0e-68	253	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647803759	305	45.89	1	305	1	316	5.0e-81	294	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647803760	507	26.59	1	507	11	553	9.0e-69	254	COG0747	ABC-type transport system, periplasmic component	556
647803761	253	37.34	11	251	1	240	9.0e-41	160	COG1414	DNA-binding transcriptional regulator, IclR family	246
647803763	240	38.1	8	236	1	226	3.0e-48	185	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647803764	326	29.3	48	315	24	295	6.0e-41	161	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
647803765	257	47.47	1	257	3	258	5.0e-79	287	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
647803766	264	31.58	4	264	17	282	3.0e-38	151	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
647803767	269	37.04	5	269	13	282	1.0e-48	186	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
647803768	395	35.66	24	389	20	391	9.0e-84	304	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
647803769	427	39.11	8	426	9	431	4.0e-115	408	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
647803770	316	31.04	2	312	21	351	5.0e-51	195	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
647803771	473	44.96	1	449	1	451	1.0e-118	420	COG1115	Na+/alanine symporter	452
647803772	307	23.08	13	291	5	281	5.0e-29	121	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
647803774	280	28.14	3	276	6	293	8.0e-24	104	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
647803775	770	31.41	135	479	1	336	8.0e-41	162	COG0642	Signal transduction histidine kinase	336
647803776	269	40.3	1	267	7	274	8.0e-41	160	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
647803777	249	41.34	1	235	2	254	5.0e-69	254	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
647803779	349	38.57	2	349	6	318	2.0e-67	249	COG4531	ABC-type Zn2+ transport system, periplasmic component/surface adhesin	318
647803781	341	56.73	1	341	1	340	0.0e+00	482	COG3938	Proline racemase	341
647803782	412	27.23	1	412	3	381	1.0e-39	157	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647803783	308	30.98	1	307	7	332	7.0e-60	224	COG3938	Proline racemase	341
647803784	319	28.96	5	297	4	289	7.0e-48	184	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
647803785	429	37.89	48	427	3	378	4.0e-65	242	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647803787	337	23.3	8	337	5	331	4.0e-39	155	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647803789	614	39.77	246	562	67	408	5.0e-44	172	COG0840	Methyl-accepting chemotaxis protein	408
647803791	295	27.61	2	294	1	291	2.0e-28	119	COG0583	DNA-binding transcriptional regulator, LysR family	297
647803792	580	41.79	195	580	15	416	2.0e-112	400	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
647803793	924	37.75	3	919	4	940	0.0e+00	821	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
647803799	1070	31.3	758	1008	7	265	4.0e-38	154	COG1018	Ferredoxin-NADP reductase	266
647803802	396	25.47	11	373	9	366	6.0e-25	109	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
647803803	1036	48.49	4	1023	5	1008	0.0e+00	898	COG0841	Multidrug efflux pump subunit AcrB	1009
647803805	439	20.52	46	391	49	383	6.0e-11	62.5	COG2814	Predicted arabinose efflux permease, MFS family	394
647803806	495	17.44	74	488	42	455	2.0e-18	87.6	COG0277	FAD/FMN-containing dehydrogenase	459
647803812	380	36.71	3	311	1	341	1.0e-68	254	COG2951	Membrane-bound lytic murein transglycosylase B	343
647803814	357	21.07	4	343	15	344	1.0e-15	77.8	COG0687	Spermidine/putrescine-binding periplasmic protein	363
647803815	142	40.71	3	141	2	140	3.0e-32	131	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
647803816	229	26.87	1	225	2	225	9.0e-26	110	COG1011	FMN phosphatase YigB, HAD superfamily	229
647803817	282	27.34	1	272	1	272	1.0e-16	80.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647803818	325	43.69	1	323	6	326	9.0e-87	313	COG1171	Threonine dehydratase	347
647803819	263	24.56	1	256	2	279	5.0e-20	91.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647803821	165	36.88	1	160	4	162	6.0e-28	116	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
647803822	361	36.99	1	338	1	344	1.0e-73	270	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
647803823	233	25.59	9	217	9	219	6.0e-33	134	COG2188	DNA-binding transcriptional regulator, GntR family	236
647803824	785	39.89	2	348	1	353	4.0e-89	323	COG1062	Zn-dependent alcohol dehydrogenase	366
647803825	105	40.4	7	105	2	100	8.0e-09	52.1	COG0640	DNA-binding transcriptional regulator, ArsR family	110
647803826	282	44.49	13	280	4	264	5.0e-77	281	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
647803827	1046	24.32	43	485	1	425	3.0e-40	161	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647803829	196	29.57	1	173	2	185	5.0e-11	61	COG0693	Putative intracellular protease/amidase	188
647803830	154	48.03	1	152	2	152	5.0e-34	137	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647803831	962	28.8	21	695	1	636	0.0e+00	489	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
647803835	590	51.45	1	545	2	539	0.0e+00	624	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
647803836	639	22.71	3	618	1	545	6.0e-52	199	COG0747	ABC-type transport system, periplasmic component	556
647803837	342	32.84	3	339	1	317	1.0e-59	223	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647803838	385	43.98	145	385	53	287	4.0e-63	235	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647803841	785	27.36	446	759	3	311	5.0e-34	140	COG0668	Small-conductance mechanosensitive channel	316
647803842	406	41.49	16	399	10	391	7.0e-92	331	COG4671	Predicted glycosyl transferase	400
647803843	414	23.58	92	412	53	380	1.0e-27	117	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647803844	368	24.67	72	366	85	381	4.0e-20	92.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647803845	194	30.24	1	194	2	206	2.0e-27	115	COG0406	Broad specificity phosphatase PhoE	208
647803846	379	31.28	1	378	10	393	4.0e-52	198	COG4671	Predicted glycosyl transferase	400
647803849	380	50.79	5	380	1	377	9.0e-113	400	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
647803851	190	46.7	11	189	4	184	7.0e-39	153	COG3709	Ribose 1,5-bisphosphokinase PhnN	192
647803852	234	64.07	8	234	4	234	1.0e-89	322	COG4778	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL	235
647803853	314	25.85	1	314	4	322	2.0e-47	183	COG0598	Mg2+ and Co2+ transporter CorA	322
647803854	256	75.2	3	256	5	258	2.0e-117	415	COG4107	ABC-type phosphonate transport system, ATPase component	258
647803855	293	75.27	1	282	9	291	0.0e+00	487	COG3627	Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase	291
647803856	367	66.94	1	367	1	367	0.0e+00	530	COG3626	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI	367
647803857	191	36.92	3	189	2	196	3.0e-36	145	COG3625	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH	196
647803858	150	55.63	3	150	1	151	2.0e-40	158	COG3624	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG	151
647803859	240	36.17	3	237	1	234	1.0e-50	193	COG2188	DNA-binding transcriptional regulator, GntR family	236
647803860	204	27.12	3	174	15	190	5.0e-22	97.7	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
647803861	436	39.35	218	430	69	283	2.0e-51	197	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
647803862	292	36.53	15	284	17	281	6.0e-48	184	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
647803863	300	33.11	4	299	15	295	1.0e-58	220	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
647803864	272	50.39	1	257	3	258	2.0e-88	318	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
647803865	310	33.55	1	302	1	297	5.0e-32	132	COG0583	DNA-binding transcriptional regulator, LysR family	297
647803866	257	44.28	1	201	1	198	3.0e-46	178	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647803867	227	53.78	5	227	2	220	1.0e-78	285	COG0036	Pentose-5-phosphate-3-epimerase	220
647803868	162	32.28	37	162	16	140	2.0e-14	72.4	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
647803869	410	37.28	5	406	3	401	9.0e-99	353	COG5441	Uncharacterized protein, UPF0261 family	401
647803870	447	50.11	1	447	30	469	1.0e-124	440	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647803871	539	38.01	1	490	4	495	4.0e-100	359	COG3333	TctA family transporter	504
647803873	314	25.79	5	313	3	315	3.0e-32	132	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
647803874	259	34.82	2	247	1	246	7.0e-41	160	COG1414	DNA-binding transcriptional regulator, IclR family	246
647803875	455	40.81	11	454	5	444	9.0e-129	453	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
647803877	429	30.11	5	427	18	442	5.0e-66	245	COG0174	Glutamine synthetase	443
647803879	419	28.29	24	418	21	411	2.0e-55	210	COG2124	Cytochrome P450	411
647803880	236	32.73	39	200	29	192	7.0e-20	91.1	COG0518	GMP synthase - Glutamine amidotransferase domain	198
647803881	216	33.65	4	213	17	223	7.0e-28	117	COG1802	DNA-binding transcriptional regulator, GntR family	230
647803882	330	46.99	31	295	1	264	3.0e-92	332	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
647803883	94	56.86	3	94	8	109	2.0e-28	116	COG3460	1,2-phenylacetyl-CoA epoxidase, PaaB subunit	117
647803884	254	38.89	6	254	18	265	8.0e-59	220	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
647803886	356	28.23	1	293	2	266	1.0e-45	177	COG1018	Ferredoxin-NADP reductase	266
647803887	287	27.86	10	285	5	282	3.0e-49	188	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
647803892	423	61.23	1	423	1	421	0.0e+00	584	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
647803894	180	23.49	1	163	2	165	3.0e-11	61.8	COG1247	L-amino acid N-acyltransferase YncA	169
647803895	434	52.73	13	433	8	425	0.0e+00	527	COG0141	Histidinol dehydrogenase	425
647803896	159	56.69	3	159	10	160	7.0e-50	189	COG5328	Uncharacterized protein, UPF0262 family	160
647803897	151	26.9	5	145	2	139	1.0e-22	99.6	COG0394	Protein-tyrosine-phosphatase	139
647803900	292	28.31	1	266	3	254	2.0e-26	112	COG0388	Predicted amidohydrolase	274
647803901	72	69.44	1	72	1	72	5.0e-24	102	COG0361	Translation initiation factor IF-1	75
647803902	193	47.37	1	187	3	191	1.0e-55	209	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
647803903	340	25.19	5	340	3	395	2.0e-27	116	COG1530	Ribonuclease G or E	487
647803904	60	34.55	3	53	10	64	1.0e-07	47.7	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
647803912	386	44.76	4	383	1	380	1.0e-110	393	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
647803914	238	35.81	13	224	13	227	3.0e-31	128	COG1802	DNA-binding transcriptional regulator, GntR family	230
647803915	325	33.12	7	325	9	319	6.0e-59	221	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
647803917	500	52.12	1	494	1	493	0.0e+00	505	COG3333	TctA family transporter	504
647803918	150	31.3	19	133	3	117	4.0e-11	61.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
647803919	692	25.66	44	689	74	745	1.0e-64	241	COG4774	Outer membrane receptor for monomeric catechols	750
647803920	1002	32.74	559	999	2	446	1.0e-103	371	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
647803921	362	29.38	7	336	16	349	4.0e-52	199	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
647803922	441	41.16	1	439	2	447	2.0e-88	319	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
647803923	167	35.48	3	157	7	161	2.0e-31	128	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
647803924	340	26.85	43	332	1	295	1.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
647803925	301	29.63	6	299	2	289	1.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
647803926	553	39.6	1	551	1	535	0.0e+00	487	COG2303	Choline dehydrogenase or related flavoprotein	542
647803927	197	33.33	17	194	1	178	4.0e-31	128	COG1386	Chromosome segregation and condensation protein ScpB	184
647803929	304	25.61	23	288	22	267	7.0e-13	68.3	COG4974	Site-specific recombinase XerD	300
647803930	310	23.17	27	272	1	230	2.0e-06	46.8	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
647803931	456	28.9	131	390	2	209	3.0e-28	119	COG1192	Cellulose biosynthesis protein BcsQ	259
647803933	504	40.24	12	500	22	527	3.0e-113	402	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647803936	438	36.75	52	432	1	377	8.0e-78	284	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647803937	182	27.33	16	176	4	161	6.0e-16	77.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647803938	328	25.22	1	327	1	329	3.0e-41	162	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647803939	218	40.09	3	218	15	230	3.0e-32	132	COG1802	DNA-binding transcriptional regulator, GntR family	230
647803940	407	72.28	6	407	8	410	0.0e+00	671	COG2871	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF	410
647803941	202	71.29	1	202	1	198	7.0e-72	263	COG2209	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE	198
647803942	217	71.22	2	206	4	208	2.0e-85	308	COG1347	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD	208
647803943	270	45.67	20	268	8	260	4.0e-69	254	COG2869	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC	264
647803944	399	54.75	2	394	1	399	2.0e-112	399	COG1805	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB	400
647803945	447	49.78	5	447	3	447	0.0e+00	480	COG1726	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA	447
647803946	343	39.13	1	342	2	336	2.0e-83	302	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
647803948	345	33.99	1	343	1	350	1.0e-64	240	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
647803949	294	32.77	166	284	5	122	2.0e-19	89.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647803950	303	36.07	7	303	14	317	9.0e-41	161	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
647803952	500	53.61	1	494	8	500	0.0e+00	609	COG1129	ABC-type sugar transport system, ATPase component	500
647803953	322	52.94	17	320	3	307	1.0e-59	223	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
647803954	243	34.69	2	241	1	245	9.0e-61	226	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647803955	241	38.04	1	239	1	251	4.0e-36	144	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647803956	349	33.06	106	344	9	244	7.0e-47	181	COG0095	Lipoate-protein ligase A	248
647803957	275	33.94	1	274	1	267	2.0e-45	176	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
647803958	230	36.7	7	224	5	222	4.0e-41	161	COG2011	ABC-type methionine transport system, permease component	222
647803961	1042	44.08	1	1026	1	1007	0.0e+00	880	COG0841	Multidrug efflux pump subunit AcrB	1009
647803962	361	33.33	1	359	15	372	8.0e-29	121	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
647803963	271	29.39	31	246	11	237	2.0e-32	132	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
647803965	417	23.9	1	414	9	430	8.0e-36	145	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
647803966	316	31.66	1	316	12	281	1.0e-52	200	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
647803967	336	35.33	16	332	4	290	3.0e-53	202	COG1175	ABC-type sugar transport system, permease component	295
647803968	382	48.91	1	366	1	338	4.0e-108	385	COG3839	ABC-type sugar transport system, ATPase component	338
647803969	295	33.56	4	284	1	285	8.0e-26	111	COG0583	DNA-binding transcriptional regulator, LysR family	297
647803970	476	29.42	1	433	1	459	1.0e-50	194	COG3119	Arylsulfatase A or related enzyme	475
647803971	164	25.4	27	151	1	126	2.0e-10	59.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
647803972	317	25.71	1	315	1	315	3.0e-25	109	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
647803974	521	35.11	31	515	21	483	6.0e-67	248	COG3333	TctA family transporter	504
647803976	408	40.62	42	391	21	374	1.0e-88	320	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
647803977	183	31.65	6	162	34	179	3.0e-14	71.5	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
647803979	86	47.06	2	86	5	88	4.0e-18	83.1	COG4327	Uncharacterized membrane protein	101
647803980	594	36.64	5	587	8	529	8.0e-122	431	COG4147	Na+(or H+)/acetate symporter ActP	529
647803981	602	33.67	5	595	7	604	3.0e-125	442	COG2905	Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains	610
647803984	301	31.65	4	277	2	273	2.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
647803985	577	29.24	72	447	25	391	3.0e-49	190	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647803986	398	47.86	1	391	1	395	4.0e-113	401	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
647803987	377	27.47	8	325	3	319	1.0e-25	111	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
647803988	643	41.14	1	639	2	642	3.0e-98	353	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
647803989	399	41.71	1	397	1	390	3.0e-85	308	COG0183	Acetyl-CoA acetyltransferase	392
647803991	432	39.9	9	429	7	394	5.0e-96	344	COG4214	ABC-type xylose transport system, permease component	394
647803992	342	46.06	1	333	1	341	1.0e-90	326	COG4213	ABC-type xylose transport system, periplasmic component	341
647803993	404	29.11	82	394	1	312	4.0e-43	169	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
647803997	527	21.74	7	501	7	511	4.0e-40	159	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647803999	164	40.49	3	162	14	176	4.0e-26	110	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
647804001	326	42.64	1	325	8	318	2.0e-46	179	COG0530	Ca2+/Na+ antiporter	320
647804002	110	52.88	1	104	1	103	6.0e-28	115	COG3492	Uncharacterized protein	104
647804003	264	32.97	1	264	6	267	1.0e-44	173	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
647804005	286	36.62	3	280	2	279	7.0e-58	217	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
647804006	330	34.08	7	330	1	355	3.0e-48	186	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
647804007	333	38.66	23	330	31	335	2.0e-63	236	COG3367	Uncharacterized conserved protein, NAD-dependent epimerase/dehydratase family	339
647804009	330	37.33	28	327	3	279	1.0e-61	230	COG2301	Citrate lyase beta subunit	283
647804012	150	46	1	150	3	151	6.0e-33	133	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647804013	218	28.78	19	216	1	205	2.0e-22	99.6	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
647804014	277	32.03	127	277	2	154	2.0e-25	109	COG3449	DNA gyrase inhibitor GyrI	154
647804015	320	58.73	1	315	1	314	4.0e-123	434	COG0825	Acetyl-CoA carboxylase alpha subunit	317
647804016	137	35.34	9	135	8	140	5.0e-20	90.4	COG4405	Uncharacterized protein YhfF	140
647804018	191	20.74	8	191	12	199	1.0e-06	46.6	COG3226	DNA-binding transcriptional regulator YbjK	204
647804019	331	53.39	1	326	1	338	3.0e-124	438	COG3839	ABC-type sugar transport system, ATPase component	338
647804020	344	24.29	1	341	3	342	9.0e-39	154	COG0673	Predicted dehydrogenase	342
647804021	279	43.06	1	279	1	281	2.0e-54	206	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
647804022	304	34.98	1	301	3	293	4.0e-42	165	COG1175	ABC-type sugar transport system, permease component	295
647804023	412	24	1	411	12	433	1.0e-37	150	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
647804024	296	39.6	1	296	1	298	4.0e-63	235	COG2103	N-acetylmuramic acid 6-phosphate (MurNAc-6-P) etherase	298
647804025	330	35.69	44	318	7	289	3.0e-37	149	COG2971	BadF-type ATPase, related to human N-acetylglucosamine kinase	301
647804026	251	42.37	15	247	3	236	3.0e-53	202	COG2188	DNA-binding transcriptional regulator, GntR family	236
647804027	342	39.88	4	341	1	340	2.0e-75	276	COG2222	Fructoselysine-6-P-deglycase FrlB and related proteins with duplicated sugar isomerase (SIS) domain	340
647804028	380	41.69	5	380	1	374	3.0e-90	325	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
647804029	354	44.31	100	354	14	266	6.0e-63	234	COG1526	Formate dehydrogenase assembly factor FdhD	266
647804030	767	22.51	19	764	13	765	1.0e-97	351	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
647804031	152	58.28	1	149	4	154	4.0e-56	210	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
647804032	750	21.28	37	743	24	720	1.0e-56	215	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
647804034	146	23.57	1	140	1	136	2.0e-08	52.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
647804036	559	29.7	37	542	22	535	1.0e-72	267	COG0747	ABC-type transport system, periplasmic component	556
647804039	326	47.68	1	322	1	317	1.0e-84	307	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647804040	313	45.89	22	313	15	287	7.0e-68	250	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647804041	324	55.03	5	317	1	315	2.0e-116	412	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
647804042	321	43.59	1	311	2	265	1.0e-89	322	COG4608	ABC-type oligopeptide transport system, ATPase component	309
647804043	263	29.06	4	263	2	264	2.0e-39	156	COG0345	Pyrroline-5-carboxylate reductase	266
647804044	206	20.22	1	175	2	179	5.0e-07	48.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647804045	681	35.85	1	366	1	363	1.0e-87	317	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
647804047	302	30.97	16	294	57	361	8.0e-54	204	COG1858	Cytochrome c peroxidase	364
647804049	281	21.54	3	259	2	261	1.0e-14	74	COG1344	Flagellin and related hook-associated protein FlgL	360
647804050	99	32.65	1	98	3	100	2.0e-19	87.7	COG1359	Quinol monooxygenase YgiN	100
647804051	509	30.54	1	497	3	500	6.0e-86	311	COG1070	Sugar (pentulose or hexulose) kinase	502
647804052	312	45.54	8	311	9	321	3.0e-76	278	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
647804053	491	45.86	1	483	4	498	0.0e+00	521	COG1129	ABC-type sugar transport system, ATPase component	500
647804054	336	40.38	1	313	1	316	6.0e-47	181	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
647804055	327	40.62	1	317	2	314	5.0e-46	178	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
647804056	338	28.21	1	311	4	316	9.0e-38	151	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
647804057	413	44.29	1	413	1	404	3.0e-115	408	COG3347	Rhamnose utilisation protein RhaD, predicted bifunctional aldolase and dehydrogenase	404
647804058	504	30.27	4	449	5	471	1.0e-72	267	COG3119	Arylsulfatase A or related enzyme	475
647804060	348	27.79	1	327	2	321	2.0e-39	156	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647804062	501	34.44	55	355	2	301	6.0e-53	202	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647804063	366	30.33	35	366	2	332	3.0e-67	249	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
647804065	194	37.63	4	194	7	200	1.0e-39	156	COG4430	Uncharacterized conserved protein YdeI, YjbR/CyaY-like superfamily, DUF1801 family	200
647804067	141	29.73	2	133	1	148	7.0e-18	83.2	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
647804068	108	38.71	9	100	18	110	6.0e-10	56	COG0640	DNA-binding transcriptional regulator, ArsR family	110
647804070	139	29.17	16	129	30	149	7.0e-09	53.2	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
647804071	123	27.45	1	102	9	110	1.0e-07	49	COG0640	DNA-binding transcriptional regulator, ArsR family	110
647804072	298	28.86	5	295	1	292	7.0e-27	114	COG0583	DNA-binding transcriptional regulator, LysR family	297
647804073	395	46.81	11	385	6	380	2.0e-97	349	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
647804074	378	47.29	1	377	1	387	1.0e-78	287	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647804080	788	64.31	84	747	1	663	0.0e+00	1084	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
647804081	451	26.57	1	441	9	404	1.0e-55	210	COG0232	dGTP triphosphohydrolase	412
647804082	348	26.11	3	348	2	381	2.0e-23	103	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647804083	227	36.93	4	226	7	246	4.0e-57	214	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
647804084	295	19.24	7	291	2	292	1.0e-06	47.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
647804085	655	29.14	342	631	2	289	3.0e-22	100	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
647804086	290	50.68	1	290	4	297	9.0e-89	320	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
647804087	292	30	11	165	19	178	4.0e-20	92.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
647804088	153	41.54	18	145	47	176	5.0e-20	90.6	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
647804089	329	35.29	8	328	14	333	9.0e-55	207	COG2855	Uncharacterized membrane protein YadS	334
647804091	564	32.9	1	534	28	533	2.0e-103	370	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
647804092	488	34.65	14	488	1	458	8.0e-94	338	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
647804093	107	30.43	1	92	10	99	3.0e-09	53.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
647804094	333	23.95	28	333	10	315	2.0e-27	116	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
647804095	193	23.2	10	184	7	186	2.0e-17	82.3	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
647804096	466	35.79	9	464	1	444	2.0e-112	399	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
647804099	270	24.37	1	252	2	280	2.0e-26	113	COG3246	Uncharacterized conserved protein, DUF849 family	298
647804100	442	44.89	1	442	10	448	0.0e+00	471	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
647804101	349	45.72	18	347	3	340	2.0e-81	296	COG2008	Threonine aldolase	342
647804102	253	30.3	1	253	1	254	3.0e-39	155	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
647804103	199	49.74	8	199	6	198	2.0e-64	238	COG0353	Recombinational DNA repair protein RecR	198
647804104	114	51.49	5	105	1	101	1.0e-19	88.3	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
647804105	314	37.12	51	312	63	325	4.0e-54	205	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
647804106	181	28.9	1	148	3	175	1.0e-22	99.9	COG1335	Nicotinamidase-related amidase	205
647804107	625	43.18	33	522	2	472	1.0e-126	447	COG2812	DNA polymerase III, gamma/tau subunits	515
647804110	631	28.98	23	548	25	508	2.0e-75	276	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
647804111	327	37.38	14	323	1	279	1.0e-62	234	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
647804115	1126	34.24	25	1112	2	1097	0.0e+00	948	COG0587	DNA polymerase III, alpha subunit	1139
647804116	433	25.96	1	272	55	336	1.0e-13	71.5	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
647804118	203	20.92	8	203	4	199	5.0e-06	44.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647804120	264	60.08	2	259	1	256	1.0e-102	366	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
647804121	409	46.6	1	407	2	411	9.0e-113	400	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
647804122	169	32.28	13	168	1	146	3.0e-33	134	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
647804123	142	30.15	1	134	1	133	2.0e-21	94.6	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
647804126	440	50.79	5	440	3	437	0.0e+00	516	COG0621	tRNA A37 methylthiotransferase MiaB	437
647804129	338	46.95	8	335	6	332	3.0e-94	338	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
647804131	170	35.71	1	167	1	153	2.0e-30	125	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
647804133	503	32.1	1	500	11	517	7.0e-72	264	COG0815	Apolipoprotein N-acyltransferase	518
647804134	393	57.04	2	393	1	386	0.0e+00	559	COG0192	S-adenosylmethionine synthetase	388
647804137	255	33.62	30	253	3	224	1.0e-48	186	COG0220	tRNA G46 methylase TrmB	227
647804138	209	25.47	1	207	4	204	9.0e-21	93.5	COG0778	Nitroreductase	207
647804139	203	48.18	1	202	3	222	3.0e-58	218	COG0283	Cytidylate kinase	222
647804140	167	17.11	3	145	2	153	1.0e-05	43.1	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
647804141	450	43.51	14	445	9	428	4.0e-106	378	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
647804143	558	53.27	7	554	2	541	0.0e+00	558	COG0539	Ribosomal protein S1	541
647804144	217	54.69	29	217	2	193	4.0e-69	254	COG3443	Periplasmic Zn/Cd-binding protein ZinT	193
647804145	95	50.54	1	93	2	93	9.0e-27	111	COG0776	Bacterial nucleoid DNA-binding protein	94
647804147	215	44.08	5	215	3	208	3.0e-51	194	COG0135	Phosphoribosylanthranilate isomerase	208
647804149	291	22.22	15	287	1	297	1.0e-15	77	COG0583	DNA-binding transcriptional regulator, LysR family	297
647804151	419	72.66	11	405	1	391	0.0e+00	705	COG0133	Tryptophan synthase beta chain	396
647804152	818	34.23	15	409	3	400	1.0e-93	338	COG0004	Ammonia channel protein AmtB	409
647804153	106	32.38	1	105	1	100	4.0e-18	83.1	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
647804154	243	49.18	1	181	2	184	2.0e-65	242	COG0193	Peptidyl-tRNA hydrolase	190
647804156	209	36.96	8	99	4	93	3.0e-13	68.7	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
647804158	402	22.39	31	402	22	418	6.0e-10	59.1	COG0738	Fucose permease	422
647804159	387	38.68	7	386	1	357	9.0e-96	344	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
647804161	453	32.14	21	299	71	335	2.0e-38	153	COG0642	Signal transduction histidine kinase	336
647804162	267	51.15	5	263	1	262	5.0e-87	314	COG0159	Tryptophan synthase alpha chain	265
647804165	365	59.25	1	365	1	372	0.0e+00	486	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
647804166	307	38.66	1	307	1	311	5.0e-75	274	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
647804167	582	33.4	57	568	94	620	3.0e-90	326	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
647804168	297	50.85	2	295	5	299	1.0e-113	403	COG1054	Predicted sulfurtransferase	308
647804169	201	31.82	5	193	4	184	4.0e-32	131	COG1335	Nicotinamidase-related amidase	205
647804171	429	29.65	8	419	1	376	2.0e-72	266	COG1488	Nicotinic acid phosphoribosyltransferase	405
647804173	536	51.87	1	523	3	536	0.0e+00	621	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
647804174	271	48.31	2	266	21	286	1.0e-61	230	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647804176	315	45.57	1	314	1	316	8.0e-84	303	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647804177	492	33.4	7	492	23	555	3.0e-78	286	COG0747	ABC-type transport system, periplasmic component	556
647804178	276	59.7	10	270	3	265	9.0e-97	346	COG0413	Ketopantoate hydroxymethyltransferase	268
647804179	280	46.07	5	280	3	282	1.0e-86	312	COG0414	Panthothenate synthetase	285
647804180	397	61.32	1	380	4	383	0.0e+00	612	COG0554	Glycerol kinase	499
647804181	417	25.91	1	354	3	344	7.0e-32	132	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647804182	184	37.42	21	169	20	172	3.0e-23	101	COG1443	Isopentenyldiphosphate isomerase	185
647804183	155	36.03	8	140	14	134	6.0e-21	93.5	COG3474	Cytochrome c2	135
647804185	150	46.67	1	150	1	148	3.0e-43	167	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
647804186	504	34.95	8	458	3	453	2.0e-116	412	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
647804187	281	34.19	1	281	3	315	1.0e-61	230	COG0627	S-formylglutathione hydrolase FrmB	316
647804188	310	31.07	1	306	2	307	8.0e-28	118	COG0679	Predicted permease	311
647804189	205	19.9	2	202	1	199	8.0e-09	53.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647804190	237	38.82	1	85	10	94	3.0e-08	52.5	COG0640	DNA-binding transcriptional regulator, ArsR family	110
647804193	472	37.34	15	465	7	480	6.0e-109	388	COG0260	Leucyl aminopeptidase	485
647804195	216	28.86	18	213	14	202	6.0e-37	147	COG0288	Carbonic anhydrase	207
647804197	340	54.3	2	332	1	333	1.0e-117	416	COG0136	Aspartate-semialdehyde dehydrogenase	334
647804200	650	33.58	27	570	4	535	4.0e-92	332	COG1574	Predicted amidohydrolase YtcJ	535
647804201	254	51.97	1	254	1	254	2.0e-86	312	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
647804202	266	51.32	1	265	2	261	2.0e-74	272	COG3971	2-keto-4-pentenoate hydratase	264
647804203	285	41.25	46	284	33	265	5.0e-60	224	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
647804204	470	27.17	14	454	1	436	2.0e-80	293	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
647804205	326	23	7	176	1	197	5.0e-08	52.2	COG2514	Catechol-2,3-dioxygenase	265
647804206	503	47.75	25	489	3	465	0.0e+00	505	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647804207	131	32.48	1	117	1	117	5.0e-22	96.5	COG3232	5-carboxymethyl-2-hydroxymuconate isomerase	127
647804208	156	33.04	40	151	12	123	1.0e-10	59.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
647804209	462	39.34	52	459	10	422	1.0e-79	291	COG2379	Glycerate-2-kinase	422
647804210	276	60.82	6	273	3	264	4.0e-113	401	COG3257	Uncharacterized protein, possibly involved in glyoxylate utilization	264
647804211	479	39.12	8	459	2	444	2.0e-83	303	COG2233	Xanthine/uracil permease	451
647804212	168	44.05	2	166	1	168	4.0e-41	160	COG3194	Ureidoglycolate hydrolase (allantoin degradation)	168
647804213	471	59.64	306	471	10	172	2.0e-58	220	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
647804215	118	61.02	1	118	7	124	4.0e-45	173	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
647804216	304	29.93	4	301	3	297	3.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
647804217	419	64.22	3	410	1	405	0.0e+00	531	COG3748	Uncharacterized membrane protein	407
647804218	434	31.62	32	433	21	420	7.0e-77	281	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
647804237	291	53.15	1	285	1	286	2.0e-99	356	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
647804241	252	48.66	1	252	1	259	4.0e-68	251	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
647804242	190	58.85	1	190	1	184	3.0e-56	211	COG2096	Cob(I)alamin adenosyltransferase	184
647804244	276	27.35	3	243	7	231	7.0e-33	134	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647804246	782	42.12	14	777	4	739	0.0e+00	743	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
647804249	391	79.04	1	391	1	394	0.0e+00	691	COG0050	Translation elongation factor EF-Tu, a GTPase	394
647804252	65	37.04	5	58	19	72	2.0e-07	47.3	COG0690	Preprotein translocase subunit SecE	73
647804253	177	49.15	1	176	1	177	3.0e-42	164	COG0250	Transcription antitermination factor NusG	178
647804254	407	22.45	1	388	1	372	1.0e-23	104	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647804255	141	64.03	2	140	1	138	3.0e-48	183	COG0080	Ribosomal protein L11	141
647804256	232	61.95	1	225	1	226	6.0e-75	274	COG0081	Ribosomal protein L1	228
647804258	172	39.88	1	171	3	175	7.0e-34	136	COG0244	Ribosomal protein L10	175
647804259	124	54.03	1	123	2	123	1.0e-18	85.7	COG0222	Ribosomal protein L7/L12	124
647804261	1410	50.99	21	850	6	808	0.0e+00	898	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
647804263	293	26.28	153	285	4	140	3.0e-06	46.3	COG2510	Uncharacterized membrane protein	140
647804266	123	73.98	1	123	7	129	1.0e-47	181	COG0048	Ribosomal protein S12	129
647804267	156	61.49	2	149	1	148	3.0e-54	204	COG0049	Ribosomal protein S7	148
647804268	706	61.1	1	705	1	691	0.0e+00	934	COG0480	Translation elongation factor EF-G, a GTPase	697
647804271	304	26.6	1	303	11	310	6.0e-36	144	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
647804275	104	73.08	1	104	1	104	1.0e-39	154	COG0051	Ribosomal protein S10	104
647804276	239	54.38	2	215	1	217	4.0e-74	271	COG0087	Ribosomal protein L3	218
647804277	205	40.95	1	205	2	211	2.0e-46	179	COG0088	Ribosomal protein L4	214
647804278	98	54.26	7	98	1	94	4.0e-21	93	COG0089	Ribosomal protein L23	94
647804280	280	62.04	1	274	1	274	1.0e-107	382	COG0090	Ribosomal protein L2	275
647804281	92	58.06	1	92	1	93	7.0e-35	138	COG0185	Ribosomal protein S19	93
647804282	126	53.1	12	124	8	120	8.0e-30	122	COG0091	Ribosomal protein L22	120
647804283	239	62.56	12	221	1	211	4.0e-78	284	COG0092	Ribosomal protein S3	233
647804284	137	63.04	1	136	2	139	2.0e-48	184	COG0197	Ribosomal protein L16/L10AE	146
647804285	235	27.67	21	223	1	203	1.0e-28	119	COG0625	Glutathione S-transferase	211
647804287	236	18.7	3	235	17	262	1.0e-13	70.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
647804289	346	30.67	13	322	6	331	2.0e-48	186	COG3608	Predicted deacylase	331
647804290	66	58.46	2	66	4	68	5.0e-10	56	COG0255	Ribosomal protein L29	69
647804291	76	56	1	75	6	80	8.0e-19	85.3	COG0186	Ribosomal protein S17	87
647804292	122	76.23	1	122	1	122	3.0e-47	180	COG0093	Ribosomal protein L14	122
647804293	101	50.48	1	101	1	103	5.0e-19	86.1	COG0198	Ribosomal protein L24	104
647804294	187	60.11	8	185	1	177	2.0e-69	254	COG0094	Ribosomal protein L5	180
647804295	101	49.18	41	101	1	61	2.0e-15	74.1	COG0199	Ribosomal protein S14	61
647804296	130	52.67	1	130	3	132	5.0e-42	163	COG0096	Ribosomal protein S8	132
647804297	177	57.06	1	176	1	176	2.0e-56	211	COG0097	Ribosomal protein L6P/L9E	178
647804298	119	55	4	119	7	125	2.0e-28	117	COG0256	Ribosomal protein L18	125
647804300	187	59.32	1	177	5	181	3.0e-58	218	COG0098	Ribosomal protein S5	181
647804301	62	52.73	5	59	1	55	4.0e-12	63.2	COG1841	Ribosomal protein L30/L7E	55
647804302	246	25.53	10	242	9	238	1.0e-25	109	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
647804305	156	47.74	1	150	1	151	2.0e-27	114	COG0200	Ribosomal protein L15	152
647804306	454	48.72	14	434	10	431	1.0e-117	416	COG0201	Preprotein translocase subunit SecY	436
647804307	193	43.98	3	192	2	178	2.0e-42	165	COG0563	Adenylate kinase or related kinase	178
647804308	122	65.29	1	121	1	121	2.0e-44	170	COG0099	Ribosomal protein S13	121
647804309	129	68.22	1	129	1	129	7.0e-47	179	COG0100	Ribosomal protein S11	129
647804310	338	47.66	9	329	1	317	6.0e-94	337	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
647804311	141	62.07	1	116	1	116	6.0e-44	169	COG0203	Ribosomal protein L17	116
647804312	112	62.5	3	110	1	112	3.0e-40	156	COG2824	Uncharacterized Zn-ribbon-containing protein	112
647804313	299	24.84	1	286	1	294	1.0e-30	127	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647804315	465	28.41	2	435	6	444	2.0e-45	176	COG0534	Na+-driven multidrug efflux pump	455
647804316	364	65.53	8	357	4	351	0.0e+00	535	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
647804317	465	39.67	5	367	2	347	1.0e-62	234	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
647804318	443	54.29	18	442	6	436	0.0e+00	571	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
647804320	464	29.76	10	464	1	450	4.0e-61	229	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
647804321	126	46.46	1	125	1	126	1.0e-15	75.2	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
647804322	348	35.29	4	323	1	289	6.0e-68	251	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
647804323	222	36.11	6	216	5	217	4.0e-37	147	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
647804324	234	45.12	1	213	27	241	9.0e-51	193	COG5387	Chaperone required for the assembly of the mitochondrial F1-ATPase	264
647804325	378	30.11	40	312	2	275	3.0e-27	116	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
647804326	422	43.74	2	422	3	397	8.0e-95	341	COG4597	ABC-type amino acid transport system, permease component	397
647804327	442	35.41	233	441	19	222	3.0e-42	166	COG0765	ABC-type amino acid transport system, permease component	222
647804328	263	64.44	23	261	3	240	7.0e-115	406	COG1126	ABC-type polar amino acid transport system, ATPase component	240
647804329	141	25.33	1	132	13	162	2.0e-07	48.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
647804331	165	31.29	5	161	4	163	2.0e-24	104	COG2062	Phosphohistidine phosphatase SixA	163
647804333	286	52.29	31	286	4	265	7.0e-79	287	COG0548	Acetylglutamate kinase	265
647804334	243	35.8	1	241	3	250	4.0e-38	151	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647804335	470	38.72	22	467	4	441	3.0e-76	279	COG3182	Uncharacterized iron-regulated membrane protein	442
647804337	216	47.69	21	215	1	195	3.0e-62	231	COG0218	GTP-binding protein EngB required for normal cell division	200
647804338	245	23.55	3	245	2	262	3.0e-19	89.2	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
647804339	611	36.01	272	601	6	313	3.0e-67	250	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
647804340	496	38	229	478	3	249	4.0e-61	229	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
647804341	311	30.18	40	311	1	263	5.0e-47	181	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
647804343	113	46.15	31	108	6	83	1.0e-21	95	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
647804344	106	39.62	1	103	7	108	3.0e-13	66.8	COG0594	RNase P protein component	117
647804347	245	27.84	21	214	9	201	5.0e-18	85	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
647804348	471	36	2	439	1	448	7.0e-103	368	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
647804349	461	24.85	123	456	1	329	2.0e-32	134	COG0642	Signal transduction histidine kinase	336
647804350	221	33.03	1	214	12	229	5.0e-27	114	COG1802	DNA-binding transcriptional regulator, GntR family	230
647804352	335	29.73	2	254	8	261	2.0e-23	103	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
647804356	304	19.93	28	296	24	307	4.0e-09	55.9	COG3344	Retron-type reverse transcriptase	328
647804371	489	26.59	64	231	59	226	9.0e-16	78.8	COG2357	ppGpp synthetase catalytic domain (RelA/SpoT-type nucleotidyltranferase)	231
647804373	325	20.91	119	295	56	267	6.0e-06	45.4	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
647804375	304	30.43	6	300	3	292	7.0e-35	141	COG0583	DNA-binding transcriptional regulator, LysR family	297
647804380	189	29.38	4	186	3	196	1.0e-29	123	COG0406	Broad specificity phosphatase PhoE	208
647804381	350	47.58	1	350	1	350	1.0e-109	390	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
647804382	584	28.89	35	573	13	534	5.0e-66	245	COG1178	ABC-type Fe3+ transport system, permease component	540
647804383	440	29.77	39	293	1	255	4.0e-27	115	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
647804384	416	31.3	1	411	1	457	2.0e-77	283	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
647804386	415	23.24	46	307	7	288	2.0e-23	104	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
647804387	474	26.8	109	458	42	431	1.0e-32	134	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
647804390	192	32.76	20	188	2	174	3.0e-22	98.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
647804396	416	24.31	17	412	30	416	5.0e-39	155	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
647804397	318	45.85	1	318	6	329	4.0e-69	255	COG0714	MoxR-like ATPase	329
647804400	352	55.56	11	350	2	339	1.0e-120	426	COG1135	ABC-type methionine transport system, ATPase component	339
647804401	224	62.21	1	217	6	222	3.0e-71	261	COG2011	ABC-type methionine transport system, permease component	222
647804402	258	54.79	4	258	8	268	1.0e-92	332	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
647804403	207	22.66	6	206	2	198	2.0e-12	66.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647804404	346	23.12	9	340	11	336	8.0e-27	114	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
647804405	222	32.08	1	209	1	204	2.0e-30	126	COG2085	Predicted dinucleotide-binding enzyme	211
647804406	257	40.23	4	257	2	246	1.0e-53	203	COG1478	F420-0:Gamma-glutamyl ligase (F420 biosynthesis)	257
647804407	217	28.21	10	204	3	181	1.0e-16	80.4	COG1920	2-phospho-L-lactate guanylyltransferase, coenzyme F420 biosynthesis enzyme, CobY/MobA/RfbA family	210
647804408	322	27.07	8	315	9	312	8.0e-44	171	COG0391	Archaeal 2-phospho-L-lactate transferase/Bacterial gluconeogenesis factor, CofD/UPF0052 family	323
647804409	425	42.43	21	389	4	367	9.0e-101	360	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
647804410	380	26.9	17	348	34	367	1.0e-60	227	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
647804411	524	52.85	2	370	1	356	2.0e-111	397	COG3288	NAD/NADP transhydrogenase alpha subunit	356
647804412	477	52.27	1	473	1	460	0.0e+00	547	COG1282	NAD/NADP transhydrogenase beta subunit	463
647804413	416	25.24	14	414	4	409	1.0e-53	203	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647804414	486	35.65	5	446	3	430	3.0e-112	398	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
647804415	496	43.1	22	493	20	486	7.0e-119	421	COG1953	Cytosine/uracil/thiamine/allantoin permease	497
647804416	97	57.29	1	95	1	96	5.0e-26	109	COG5470	Uncharacterized conserved protein, DUF1330 family	96
647804419	359	19.08	92	349	12	260	1.0e-11	64.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
647804420	345	20.09	105	335	40	261	1.0e-10	61.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
647804421	826	40.07	17	293	18	294	2.0e-64	241	COG3452	Extracellular (periplasmic) sensor domain CHASE (specificity unknown)	297
647804422	260	51.74	3	256	2	258	2.0e-76	279	COG4559	ABC-type hemin transport system, ATPase component	259
647804423	362	43.32	26	360	3	333	3.0e-56	212	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
647804424	281	50.18	7	281	23	299	6.0e-73	267	COG4558	ABC-type hemin transport system, periplasmic component	300
647804425	351	43.64	1	345	1	345	8.0e-97	347	COG3720	Putative heme degradation protein	349
647804426	667	21.14	2	667	3	699	3.0e-27	117	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
647804428	226	27.96	14	199	11	195	1.0e-22	100	COG0811	Biopolymer transport protein ExbB/TolQ	216
647804429	130	28	1	120	1	122	2.0e-09	54.8	COG0848	Biopolymer transport protein ExbD	137
647804430	131	21.64	1	127	1	133	4.0e-06	44.1	COG0848	Biopolymer transport protein ExbD	137
647804431	291	22.27	69	288	19	237	2.0e-10	60.5	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
647804433	310	29.05	3	293	1	292	2.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
647804434	415	25.41	1	415	2	384	3.0e-35	143	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647804435	325	26.14	1	324	4	328	1.0e-43	170	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647804437	434	30.77	54	429	3	376	3.0e-61	229	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647804438	910	36.16	514	853	44	408	3.0e-42	167	COG0840	Methyl-accepting chemotaxis protein	408
647804439	696	41.67	290	573	1	287	1.0e-70	261	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
647804440	392	37.25	1	390	1	390	3.0e-74	272	COG0183	Acetyl-CoA acetyltransferase	392
647804441	264	28.23	13	256	2	246	9.0e-30	124	COG1414	DNA-binding transcriptional regulator, IclR family	246
647804442	242	34.25	26	240	22	238	4.0e-37	148	COG5255	Uncharacterized protein	239
647804443	320	35.53	4	318	9	318	7.0e-56	211	COG0837	Glucokinase	320
647804445	232	37.61	12	222	18	233	8.0e-29	120	COG2186	DNA-binding transcriptional regulator, FadR family	241
647804446	278	28.31	5	270	1	253	4.0e-08	52.3	COG0730	Uncharacterized membrane protein YfcA	258
647804447	413	29.75	97	403	1	311	1.0e-36	148	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
647804448	338	28.31	1	325	10	316	8.0e-39	154	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
647804449	355	38.36	36	352	5	311	4.0e-51	195	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
647804451	212	27.05	1	203	61	267	1.0e-43	169	COG1072	Panthothenate kinase	283
647804452	221	53.81	1	221	1	221	1.0e-78	286	COG3822	D-lyxose ketol-isomerase	225
647804453	177	24	2	165	1	171	6.0e-19	87.2	COG0563	Adenylate kinase or related kinase	178
647804454	291	22.55	1	282	1	296	1.0e-20	93.5	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647804455	134	31.11	2	133	1	132	5.0e-16	77	COG3791	Uncharacterized conserved protein	133
647804456	215	49.03	9	213	3	208	2.0e-52	198	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
647804457	603	41.25	9	601	4	571	0.0e+00	601	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
647804458	483	51.13	5	479	2	481	0.0e+00	612	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
647804459	536	46.56	38	528	1	446	0.0e+00	488	COG0166	Glucose-6-phosphate isomerase	446
647804461	217	49	4	201	5	196	1.0e-59	222	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
647804462	214	38.6	1	214	2	229	9.0e-42	163	COG0830	Urease accessory protein UreF	229
647804463	168	43.36	14	153	14	155	1.0e-26	112	COG2371	Urease accessory protein UreE	155
647804465	570	75.57	2	570	1	568	0.0e+00	1026	COG0804	Urease alpha subunit	568
647804467	101	65.35	1	101	1	101	9.0e-43	164	COG0832	Urease beta subunit	106
647804468	195	53.44	9	195	16	200	2.0e-23	101	COG2370	Hydrogenase/urease accessory protein HupE	201
647804469	100	71	1	100	1	100	8.0e-42	161	COG0831	Urease gamma subunit	100
647804470	259	35.91	2	257	16	269	1.0e-45	176	COG0829	Urease accessory protein UreH	269
647804471	370	51.08	1	365	5	369	5.0e-111	394	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
647804473	668	34.12	9	496	18	519	1.0e-94	341	COG2936	Predicted acyl esterase	563
647804476	234	24.31	48	219	49	221	3.0e-07	48.8	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
647804477	354	41.32	85	322	35	265	2.0e-53	203	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
647804483	202	24.86	18	192	10	190	6.0e-20	90.8	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
647804485	1003	30.99	27	670	2	615	4.0e-105	376	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
647804486	197	44.77	1	164	8	157	4.0e-36	144	COG0437	Fe-S-cluster-containing dehydrogenase component	203
647804487	404	29.34	156	395	2	213	2.0e-36	146	COG2864	Cytochrome b subunit of formate dehydrogenase	218
647804488	428	32.81	300	425	9	134	2.0e-20	93.9	COG3474	Cytochrome c2	135
647804490	450	40.83	16	450	3	456	2.0e-110	393	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
647804492	246	21.92	1	210	2	205	1.0e-15	77.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647804493	240	28.97	4	240	5	256	1.0e-37	149	COG0300	Short-chain dehydrogenase	265
647804495	405	19.57	13	399	25	437	4.0e-22	99.5	COG2211	Na+/melibiose symporter or related transporter	467
647804497	386	41.46	106	384	1	283	3.0e-71	262	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
647804498	257	35.43	8	254	2	249	2.0e-35	142	COG3496	Uncharacterized conserved protein, DUF1365 family	261
647804499	436	41.88	5	436	3	436	8.0e-105	374	COG2907	Predicted NAD/FAD-binding protein	447
647804500	185	36.16	13	184	5	180	2.0e-25	109	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
647804501	211	35.35	4	210	1	215	6.0e-31	127	COG3806	Anti-sigma factor ChrR, cupin superfamily	216
647804502	334	61.98	2	332	1	332	1.0e-127	449	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
647804504	577	20.04	89	533	43	488	3.0e-28	120	COG0366	Glycosidase	505
647804505	85	63.53	1	85	1	85	3.0e-25	106	COG3811	Uncharacterized protein YjhX, UPF0386 family	85
647804506	163	50.88	1	163	4	169	2.0e-35	142	COG3153	Predicted N-acetyltransferase YhbS	171
647804508	259	37.6	4	237	8	263	5.0e-29	121	COG3769	Predicted mannosyl-3-phosphoglycerate phosphatase, HAD superfamily	274
647804509	555	38.67	27	551	14	512	9.0e-106	378	COG1292	Choline-glycine betaine transporter	537
647804511	232	42.74	8	231	31	262	7.0e-64	237	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
647804514	491	41.67	15	488	1	473	7.0e-123	434	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
647804515	335	54.68	1	329	1	338	5.0e-124	437	COG3839	ABC-type sugar transport system, ATPase component	338
647804516	276	37.86	1	276	2	281	6.0e-49	188	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
647804517	288	32.28	5	285	7	290	1.0e-42	166	COG1175	ABC-type sugar transport system, permease component	295
647804519	436	23.89	6	425	14	424	2.0e-36	147	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
647804520	343	29.85	8	342	2	328	2.0e-56	212	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
647804521	758	34.3	414	732	65	408	6.0e-44	172	COG0840	Methyl-accepting chemotaxis protein	408
647804522	924	22.81	503	779	68	330	5.0e-21	97.2	COG0642	Signal transduction histidine kinase	336
647804524	285	29.17	23	247	6	243	5.0e-18	85.1	COG3327	DNA-binding transcriptional regulator PaaX (phenylacetic acid degradation)	291
647804525	676	28.4	6	507	1	472	1.0e-65	244	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647804526	261	42.69	1	258	3	257	2.0e-48	186	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647804527	151	33.08	3	131	1	132	3.0e-18	84.7	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
647804528	436	55.87	14	436	15	438	0.0e+00	514	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
647804529	198	21.58	1	190	2	189	6.0e-09	54.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647804532	624	30.13	467	617	39	189	1.0e-15	78.3	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
647804533	342	49.84	3	318	1	314	3.0e-103	368	COG0180	Tryptophanyl-tRNA synthetase	314
647804534	228	20.18	3	226	7	223	1.0e-05	43.6	COG0705	Membrane associated serine protease, rhomboid family	228
647804535	515	36.7	1	509	4	518	7.0e-82	298	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
647804536	907	38.92	25	904	1	867	0.0e+00	749	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
647804537	394	22.26	66	363	26	340	1.0e-10	61.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
647804538	338	47.1	60	334	2	274	2.0e-80	292	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
647804539	124	36.7	16	122	5	113	4.0e-15	73.7	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
647804540	311	39.81	1	311	1	316	2.0e-64	239	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
647804541	295	32.59	1	295	1	311	1.0e-34	140	COG0657	Acetyl esterase/lipase	312
647804542	500	53.07	14	497	1	485	0.0e+00	564	COG0606	Predicted ATPase with chaperone activity	490
647804543	226	26.63	12	205	8	205	4.0e-15	75.2	COG0625	Glutathione S-transferase	211
647804544	193	28.34	1	177	1	185	1.0e-21	96.4	COG0406	Broad specificity phosphatase PhoE	208
647804545	181	46.86	13	179	1	175	1.0e-45	175	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
647804546	292	38.13	13	286	74	337	4.0e-52	198	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
647804547	288	21.03	30	266	41	269	2.0e-12	66.6	COG3016	Uncharacterized iron-regulated protein	295
647804548	403	48.48	1	392	1	387	5.0e-107	381	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
647804550	836	39.26	212	476	4	267	3.0e-61	230	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
647804551	163	44	8	157	4	146	3.0e-36	144	COG0756	dUTPase	148
647804552	358	48	102	347	5	254	2.0e-71	262	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
647804553	263	32.21	1	258	4	265	5.0e-32	131	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
647804554	268	41.67	38	265	12	222	1.0e-51	197	COG0765	ABC-type amino acid transport system, permease component	222
647804555	671	44.07	1	670	3	683	0.0e+00	727	COG0339	Zn-dependent oligopeptidase	683
647804556	308	33.23	2	308	6	324	2.0e-52	199	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
647804557	136	55.56	1	135	3	137	5.0e-49	186	COG3565	Predicted dioxygenase of extradiol dioxygenase family	138
647804558	282	30.9	1	273	1	285	6.0e-22	98.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
647804559	379	40.22	20	379	13	374	1.0e-75	277	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
647804560	648	31.89	3	603	1	585	2.0e-111	396	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
647804562	315	29.45	14	279	8	279	3.0e-35	142	COG1792	Cell shape-determining protein MreC	284
647804563	348	61.42	9	344	3	339	2.0e-121	428	COG1077	Actin-like ATPase involved in cell morphogenesis	342
647804565	259	42.42	2	259	1	262	6.0e-64	237	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
647804566	589	37.96	279	577	85	408	1.0e-43	171	COG0840	Methyl-accepting chemotaxis protein	408
647804567	737	63.36	6	736	5	739	0.0e+00	1012	COG2838	Monomeric isocitrate dehydrogenase	744
647804568	429	22.12	62	399	40	369	1.0e-16	81.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647804569	201	39.33	30	201	4	171	2.0e-38	152	COG3807	SH3-like domain	171
647804570	328	45.57	5	326	2	324	1.0e-92	333	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
647804571	598	44.12	59	597	11	538	0.0e+00	537	COG0405	Gamma-glutamyltranspeptidase	539
647804572	468	38.19	26	465	8	456	1.0e-91	330	COG0277	FAD/FMN-containing dehydrogenase	459
647804575	835	33.5	432	832	1	378	9.0e-80	292	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
647804576	321	21.19	159	299	8	158	4.0e-07	49.3	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
647804579	361	27.49	1	350	4	374	2.0e-32	133	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647804580	315	37.66	14	307	10	313	3.0e-63	235	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
647804581	203	25.53	20	203	7	191	2.0e-08	52.7	COG0558	Phosphatidylglycerophosphate synthase	192
647804583	391	36.47	34	364	9	345	1.0e-65	243	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
647804584	306	50	9	306	8	304	8.0e-70	257	COG1079	ABC-type uncharacterized transport system, permease component	304
647804585	360	43.02	2	352	1	347	3.0e-69	255	COG4603	ABC-type uncharacterized transport system, permease component	356
647804586	506	47.11	4	497	2	501	0.0e+00	577	COG3845	ABC-type uncharacterized transport system, ATPase component	501
647804587	318	26.16	12	306	4	256	1.0e-27	117	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
647804588	789	56.78	3	788	19	777	0.0e+00	982	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
647804591	607	35.6	96	579	15	526	7.0e-93	334	COG0659	Sulfate permease or related transporter, MFS superfamily	554
647804592	206	27.72	3	175	7	190	1.0e-22	99	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
647804593	201	31.55	9	195	4	176	1.0e-28	120	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
647804594	166	39.88	1	159	3	164	3.0e-29	121	COG3153	Predicted N-acetyltransferase YhbS	171
647804598	162	40.13	1	157	1	138	3.0e-30	124	COG5319	Uncharacterized protein	142
647804599	213	29.27	1	183	6	204	2.0e-22	99.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647804601	149	50.68	6	149	2	147	5.0e-45	173	COG0698	Ribose 5-phosphate isomerase RpiB	151
647804603	316	64	7	305	4	291	0.0e+00	497	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
647804605	687	43.18	1	687	3	691	0.0e+00	733	COG0751	Glycyl-tRNA synthetase, beta subunit	691
647804607	854	24.58	22	840	20	739	5.0e-110	392	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
647804609	306	27.83	26	137	3	117	6.0e-11	61.8	COG1539	Dihydroneopterin aldolase	121
647804610	331	49.81	71	331	8	265	5.0e-71	261	COG0294	Dihydropteroate synthase	274
647804611	483	44.64	33	483	2	462	1.0e-115	410	COG1109	Phosphomannomutase	464
647804613	340	63.02	1	338	3	338	0.0e+00	510	COG0059	Ketol-acid reductoisomerase	338
647804614	151	37.09	1	151	5	154	4.0e-23	100	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647804615	152	40.41	1	146	3	147	3.0e-24	104	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647804616	374	26.27	24	373	29	364	2.0e-55	210	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
647804617	399	31.39	7	397	4	384	8.0e-52	197	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647804619	214	21.52	6	213	1	222	2.0e-19	89.6	COG1011	FMN phosphatase YigB, HAD superfamily	229
647804620	222	34.08	1	220	4	226	2.0e-30	125	COG1802	DNA-binding transcriptional regulator, GntR family	230
647804621	596	23.4	173	573	1	403	2.0e-37	150	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
647804622	386	54.76	8	385	1	366	0.0e+00	519	COG0505	Carbamoylphosphate synthase small subunit	368
647804623	157	51.66	1	151	1	147	3.0e-37	147	COG1610	Uncharacterized conserved protein YqeY	148
647804624	172	26.03	21	162	20	160	1.0e-08	53	COG5488	Uncharacterized membrane protein	164
647804625	552	52.35	14	541	3	515	0.0e+00	547	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
647804627	138	45.26	6	138	1	137	1.0e-33	135	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
647804628	131	20.86	3	125	2	138	3.0e-06	44	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
647804629	527	50.61	12	420	1	409	1.0e-118	420	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
647804630	510	50.79	4	507	2	505	0.0e+00	610	COG3046	Uncharacterized protein related to deoxyribodipyrimidine photolyase	505
647804632	481	36.84	154	286	7	139	8.0e-18	85.4	COG4642	Uncharacterized conserved protein	139
647804633	552	38.14	260	541	1	268	4.0e-62	232	COG0171	NH3-dependent NAD+ synthetase	268
647804634	433	29.98	15	432	1	382	5.0e-50	192	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647804635	312	26.04	99	287	30	212	8.0e-13	68	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647804636	441	38.48	3	433	11	456	3.0e-102	365	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
647804637	394	26.99	1	371	23	405	1.0e-45	177	COG4325	Uncharacterized membrane protein	464
647804639	155	37.59	1	140	1	140	1.0e-30	125	COG1959	DNA-binding transcriptional regulator, IscR family	150
647804640	846	36.43	9	844	2	828	0.0e+00	535	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
647804641	234	53.98	5	228	3	228	3.0e-75	274	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
647804642	225	31.25	28	212	10	211	1.0e-17	83.4	COG2755	Lysophospholipase L1 or related esterase	216
647804644	307	34.82	1	303	2	306	4.0e-72	265	COG4286	Uncharacterized protein, UPF0160 family	306
647804652	547	34.5	11	542	1	521	0.0e+00	529	COG1384	Lysyl-tRNA synthetase, class I	521
647804654	497	31.33	65	453	41	442	2.0e-43	170	COG2027	D-alanyl-D-alanine carboxypeptidase	470
647804655	201	35.79	11	196	1	170	6.0e-37	147	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
647804658	555	44.92	5	537	1	530	0.0e+00	574	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
647804660	211	49	5	203	3	202	8.0e-62	230	COG4136	ABC-type uncharacterized transport system YnjBCD, ATPase component	213
647804661	565	36.5	16	563	10	550	5.0e-93	335	COG4135	ABC-type uncharacterized transport system YnjBCD, permease component	551
647804662	399	44.25	1	399	1	384	8.0e-87	314	COG4134	ABC-type uncharacterized transport system YnjBCD, periplasmic component	384
647804663	351	48.08	41	347	14	324	6.0e-111	394	COG0379	Quinolinate synthase	324
647804664	531	47.02	4	517	2	518	0.0e+00	499	COG0029	Aspartate oxidase	518
647804665	282	51.61	6	282	1	277	4.0e-89	321	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
647804666	310	31.88	3	295	2	295	5.0e-32	132	COG0583	DNA-binding transcriptional regulator, LysR family	297
647804667	191	77.63	40	191	3	154	6.0e-67	246	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
647804668	217	35.61	12	210	1	203	3.0e-28	118	COG0625	Glutathione S-transferase	211
647804669	313	17.3	8	190	1	158	2.0e-08	53.9	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
647804670	764	42.22	394	748	4	352	2.0e-103	370	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
647804671	249	34.32	10	238	9	233	2.0e-34	139	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647804672	164	28.57	32	143	6	116	6.0e-11	60.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
647804673	267	34.65	12	264	10	257	3.0e-44	172	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647804674	385	42.82	12	377	12	386	6.0e-64	238	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647804675	537	34.24	34	537	5	517	2.0e-108	386	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
647804676	376	31.09	12	352	1	357	7.0e-38	151	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
647804677	306	40.2	6	306	6	294	4.0e-39	155	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
647804678	327	36.79	6	318	4	307	2.0e-39	156	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
647804679	249	46	2	247	1	250	1.0e-70	259	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
647804680	228	46.84	1	228	1	237	8.0e-67	246	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
647804681	134	23.88	1	132	5	137	2.0e-19	88.4	COG0824	Acyl-CoA thioesterase FadM	137
647804682	131	36.36	1	130	3	128	2.0e-20	91.5	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
647804683	332	37.01	1	332	1	326	2.0e-55	209	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647804686	824	37.98	219	471	13	267	4.0e-59	223	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
647804687	279	62.78	18	279	1	262	1.0e-96	346	COG3483	Tryptophan 2,3-dioxygenase (vermilion)	262
647804688	396	51.3	5	385	21	406	7.0e-124	437	COG3844	Kynureninase	407
647804690	116	28.07	10	116	2	115	1.0e-16	78.1	COG1733	DNA-binding transcriptional regulator, HxlR family	120
647804691	254	26.02	7	250	7	228	4.0e-35	141	COG2243	Precorrin-2 methylase	234
647804693	232	33.76	1	230	3	233	3.0e-33	135	COG5446	Uncharacterized membrane protein, predicted cobalt tansporter CbtA	233
647804695	118	33.04	4	103	22	135	2.0e-10	58.1	COG5469	Predicted metal-binding protein	143
647804696	245	44.02	1	234	2	231	2.0e-57	215	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
647804697	438	47.17	6	437	1	439	0.0e+00	473	COG1797	Cobyrinic acid a,c-diamide synthase	451
647804698	264	51	1	249	3	252	2.0e-91	329	COG2875	Precorrin-4 methylase	254
647804700	402	42.16	222	402	3	186	3.0e-44	173	COG2242	Precorrin-6B methylase 2	187
647804701	253	39.69	1	250	2	249	1.0e-52	200	COG2099	Precorrin-6x reductase	257
647804702	265	44.35	7	253	3	245	2.0e-74	272	COG1010	Precorrin-3B methylase	249
647804703	245	39.17	9	245	2	234	1.0e-55	209	COG2243	Precorrin-2 methylase	234
647804704	209	49.76	2	205	1	203	1.0e-57	216	COG2082	Precorrin isomerase	210
647804705	385	23.65	11	366	36	460	3.0e-37	149	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
647804707	344	34.71	7	336	1	313	6.0e-72	264	COG0523	GTPase, G3E family	323
647804708	159	37.7	12	127	18	138	6.0e-22	97	COG5469	Predicted metal-binding protein	143
647804709	215	54.27	17	215	2	198	4.0e-69	254	COG2109	ATP:corrinoid adenosyltransferase	198
647804710	526	46.18	12	517	14	499	0.0e+00	507	COG0578	Glycerol-3-phosphate dehydrogenase	532
647804711	264	40.32	1	253	1	253	4.0e-61	228	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
647804713	357	42.06	4	356	8	364	3.0e-76	278	COG3490	Uncharacterized protein	366
647804714	338	28.53	7	338	8	359	8.0e-36	144	COG3489	Predicted periplasmic lipoprotein	359
647804715	502	55.86	28	502	6	481	0.0e+00	578	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
647804716	161	58.97	1	156	1	156	3.0e-52	197	COG2193	Bacterioferritin (cytochrome b1)	157
647804717	422	63.49	1	422	19	446	0.0e+00	516	COG3487	Uncharacterized iron-regulated protein	446
647804720	280	30.98	3	276	2	297	6.0e-25	108	COG0583	DNA-binding transcriptional regulator, LysR family	297
647804721	298	22.78	28	298	5	250	1.0e-11	64	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
647804722	429	21.38	10	423	1	388	4.0e-07	49.8	COG2814	Predicted arabinose efflux permease, MFS family	394
647804723	194	37.77	3	190	2	184	2.0e-44	172	COG3575	Uncharacterized protein	184
647804724	573	41.4	1	565	4	554	0.0e+00	566	COG0143	Methionyl-tRNA synthetase	558
647804727	562	31.49	3	504	9	516	4.0e-53	202	COG2268	Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain	548
647804729	413	19.71	46	383	49	390	3.0e-07	50.2	COG2814	Predicted arabinose efflux permease, MFS family	394
647804730	133	27.45	23	124	7	102	1.0e-09	55.3	COG0607	Rhodanese-related sulfurtransferase	110
647804731	348	36.54	1	348	1	315	6.0e-67	247	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
647804732	343	40.37	9	325	5	326	8.0e-74	270	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
647804733	305	50.67	5	299	1	297	8.0e-99	353	COG3246	Uncharacterized conserved protein, DUF849 family	298
647804734	186	37.21	14	185	7	171	4.0e-34	137	COG3040	Bacterial lipocalin	174
647804735	491	30.77	1	295	2	293	6.0e-55	208	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
647804738	333	20.55	40	327	38	325	4.0e-25	109	COG3239	Fatty acid desaturase	343
647804742	143	43.1	18	133	10	125	1.0e-31	129	COG5349	Uncharacterized conserved protein, DUF983 family	126
647804744	206	39.56	22	200	1	181	2.0e-25	109	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
647804747	467	32.14	17	459	3	433	2.0e-58	220	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
647804749	230	31.17	1	230	2	220	9.0e-25	107	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
647804750	519	49.33	1	518	9	526	0.0e+00	563	COG5598	Trimethylamine:corrinoid methyltransferase	526
647804753	342	41.67	147	322	3	181	4.0e-36	145	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
647804754	693	27.28	8	687	35	765	1.0e-100	360	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
647804755	434	36.8	14	420	1	411	5.0e-90	325	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
647804758	580	39.8	59	547	7	484	4.0e-95	342	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
647804759	327	52.35	12	317	2	317	5.0e-105	374	COG1494	Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase or related protein	332
647804760	428	46.81	4	324	3	331	1.0e-90	327	COG0460	Homoserine dehydrogenase	333
647804762	209	25.41	14	198	1	185	3.0e-09	55.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647804766	303	39.2	1	299	2	276	7.0e-59	220	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
647804769	451	41.14	16	451	5	456	8.0e-109	387	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
647804770	484	33.7	10	468	18	469	8.0e-77	281	COG1757	Na+/H+ antiporter NhaC	485
647804771	311	38.22	1	308	4	316	2.0e-62	232	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
647804772	424	27.74	9	410	5	370	2.0e-36	147	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647804773	216	37.21	31	115	1	86	5.0e-08	51.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
647804776	464	27.92	17	449	18	448	1.0e-39	157	COG0534	Na+-driven multidrug efflux pump	455
647804782	476	37.29	6	476	1	410	4.0e-95	342	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
647804785	421	30.69	32	405	1	384	6.0e-53	202	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647804786	92	43.37	1	80	2	84	9.0e-21	91.9	COG4311	Sarcosine oxidase delta subunit	97
647804787	981	37.12	589	981	2	379	9.0e-86	312	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
647804788	185	24.74	2	183	4	189	1.0e-15	76.1	COG4583	Sarcosine oxidase gamma subunit	189
647804790	669	42	3	421	2	404	3.0e-103	369	COG0358	DNA primase (bacterial type)	568
647804791	664	52.24	333	663	10	342	7.0e-96	345	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
647804795	143	41.13	4	143	3	137	1.0e-36	145	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
647804796	155	53.55	1	155	1	155	2.0e-52	197	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
647804797	366	41.18	146	364	1	217	5.0e-53	202	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
647804798	679	37.79	51	675	30	671	3.0e-118	419	COG3563	Capsule polysaccharide export protein KpsC/LpsZ	671
647804799	378	29	83	280	48	239	7.0e-24	105	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
647804800	434	33.85	11	399	12	398	1.0e-67	250	COG3562	Capsule polysaccharide modification protein KpsS	403
647804802	201	45.73	1	197	1	191	3.0e-59	221	COG0307	Riboflavin synthase alpha chain	204
647804805	380	59.7	23	223	3	202	2.0e-75	276	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
647804806	174	40.67	9	154	3	152	8.0e-33	133	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
647804807	164	32.88	20	163	9	149	2.0e-20	92.3	COG0781	Transcription termination factor NusB	151
647804809	549	46.98	41	549	7	502	0.0e+00	485	COG1292	Choline-glycine betaine transporter	537
647804811	182	49.59	39	161	26	148	1.0e-30	126	COG5321	Uncharacterized protein	164
647804816	345	42.38	6	330	2	289	4.0e-75	275	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
647804818	542	24.21	1	489	5	459	1.0e-54	208	COG3119	Arylsulfatase A or related enzyme	475
647804819	268	29.07	6	261	1	246	5.0e-24	104	COG1414	DNA-binding transcriptional regulator, IclR family	246
647804820	436	29.34	38	416	2	386	2.0e-44	173	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647804821	133	28.32	16	127	1	107	2.0e-12	64.9	COG0607	Rhodanese-related sulfurtransferase	110
647804825	206	53.37	1	205	1	205	2.0e-57	215	COG0522	Ribosomal protein S4 or related protein	205
647804828	155	23.38	1	150	1	150	5.0e-06	44.1	COG1247	L-amino acid N-acyltransferase YncA	169
647804829	153	36.36	1	153	2	154	3.0e-29	120	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647804830	487	29.9	51	464	22	404	1.0e-70	260	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
647804833	362	40.61	6	361	2	356	7.0e-87	314	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
647804834	307	40.21	5	289	1	279	5.0e-68	251	COG0287	Prephenate dehydrogenase	279
647804835	275	27.33	4	275	2	300	1.0e-32	133	COG3921	Uncharacterized conserved protein	300
647804836	337	20.94	2	334	14	338	5.0e-08	52.3	COG4093	Uncharacterized protein	338
647804837	175	51.72	4	175	13	184	2.0e-43	168	COG3703	Cation transport regulator ChaC	190
647804839	784	26.73	585	784	44	243	1.0e-25	112	COG1360	Flagellar motor protein MotB	244
647804842	778	46.55	4	760	2	784	0.0e+00	849	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
647804843	271	28.93	28	244	26	252	3.0e-19	89.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647804845	188	38.2	8	185	2	178	2.0e-31	128	COG0712	FoF1-type ATP synthase, delta subunit	178
647804846	513	66.47	1	513	1	501	0.0e+00	789	COG0056	FoF1-type ATP synthase, alpha subunit	504
647804847	291	45.17	5	291	1	286	3.0e-83	301	COG0224	FoF1-type ATP synthase, gamma subunit	287
647804848	474	74.47	4	472	2	468	0.0e+00	800	COG0055	FoF1-type ATP synthase, beta subunit	468
647804849	137	29.01	4	132	3	133	3.0e-18	84.5	COG0355	FoF1-type ATP synthase, epsilon subunit	135
647804853	814	47.98	71	813	1	709	0.0e+00	713	COG2217	Cation transport ATPase	713
647804855	292	21.37	35	277	38	280	3.0e-08	53	COG5006	Threonine/homoserine efflux transporter RhtA	292
647804856	235	32.41	19	229	16	222	5.0e-22	98	COG2045	Phosphosulfolactate phosphohydrolase or related enzyme	230
647804857	340	54.21	5	324	3	314	6.0e-107	380	COG0462	Phosphoribosylpyrophosphate synthetase	314
647804858	204	37.24	4	196	6	197	1.0e-31	130	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
647804859	278	22.89	1	274	1	278	2.0e-14	73.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647804860	156	55.17	12	156	9	150	1.0e-45	175	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
647804863	325	27.91	20	318	1	295	5.0e-32	132	COG0583	DNA-binding transcriptional regulator, LysR family	297
647804864	333	27.25	1	330	2	328	1.0e-36	146	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647804865	187	26.44	14	187	7	174	6.0e-09	54.2	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647804866	428	41.76	50	425	5	377	1.0e-69	257	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647804867	342	34.87	1	337	4	309	2.0e-62	232	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
647804868	116	33.93	12	116	18	129	1.0e-26	111	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
647804869	414	21.65	1	409	4	380	2.0e-26	113	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647804870	806	31.17	415	806	2	379	2.0e-80	294	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
647804871	1145	19.79	273	1134	171	975	5.0e-33	137	COG4717	Uncharacterized protein YhaN	984
647804872	411	25.96	2	386	1	390	1.0e-32	134	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
647804874	384	25.75	16	375	1	353	2.0e-38	153	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
647804875	304	27.46	9	298	1	293	3.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
647804876	270	33.33	37	252	4	216	1.0e-34	140	COG2049	Allophanate hydrolase subunit 1	223
647804877	341	37.86	5	305	1	306	4.0e-58	218	COG1984	Allophanate hydrolase subunit 2	314
647804878	257	51.2	3	252	2	251	3.0e-77	281	COG1540	Lactam utilization protein B (function unknown)	252
647804879	604	67.18	124	575	4	432	0.0e+00	738	COG0422	Thiamine biosynthesis protein ThiC	432
647804881	325	53.65	8	320	11	323	3.0e-110	391	COG0502	Biotin synthase or related enzyme	335
647804883	154	48.91	1	137	3	137	3.0e-43	167	COG1832	Predicted CoA-binding protein	140
647804886	262	30.77	15	258	10	252	3.0e-43	168	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
647804888	105	50.55	4	94	1	91	7.0e-23	98.7	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
647804889	316	64.31	64	315	1	255	2.0e-112	398	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
647804890	147	37.5	22	124	12	115	2.0e-15	75.3	COG3439	Uncharacterized conserved protein, DUF302 family	137
647804893	240	53.97	1	239	2	239	3.0e-81	295	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
647804895	129	39.84	3	129	40	162	4.0e-19	87	COG4731	Uncharacterized conserved protein, DUF2147 family	162
647804897	178	26.83	1	161	3	153	6.0e-10	57.2	COG1225	Peroxiredoxin	157
647804898	248	33.33	132	247	6	122	4.0e-15	75.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647804899	212	47.64	1	212	2	204	2.0e-66	245	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
647804900	202	20.62	3	196	1	192	5.0e-10	58.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647804902	195	63.59	1	195	3	195	3.0e-82	297	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
647804904	450	40.72	1	443	10	449	0.0e+00	461	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
647804911	198	27.81	35	198	16	199	7.0e-10	57.3	COG3637	Opacity protein and related surface antigens	199
647804912	1146	62.97	4	1146	7	1148	0.0e+00	1756	COG1038	Pyruvate carboxylase	1149
647804914	386	35.31	10	378	1	344	2.0e-66	246	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
647804916	811	42.65	29	693	1	649	0.0e+00	622	COG0210	Superfamily I DNA or RNA helicase	655
647804917	155	22.7	8	143	2	138	1.0e-05	42.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
647804919	356	43.04	101	326	47	265	1.0e-52	201	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
647804921	360	43.97	19	360	1	316	8.0e-57	214	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
647804922	463	42.45	3	455	2	450	4.0e-104	371	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
647804923	494	38.57	22	489	8	475	1.0e-102	366	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
647804924	593	32.21	48	578	16	596	1.0e-97	351	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
647804926	329	47.6	8	310	3	314	3.0e-96	345	COG0275	16S rRNA C1402 N4-methylase RsmH	314
647804927	285	30.46	122	272	1	140	3.0e-23	102	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
647804943	142	31.39	1	137	1	135	7.0e-16	76.6	COG4387	Mu-like prophage protein gp36	139
647804945	298	46.75	1	297	2	308	1.0e-83	303	COG4397	Mu-like prophage major head subunit gpT	308
647804947	372	26.06	39	365	24	356	2.0e-16	80.5	COG4388	Mu-like prophage I protein	357
647804949	159	21.05	7	158	8	136	5.0e-09	54.2	COG5005	Mu-like prophage protein gpG	140
647804951	553	31.52	39	545	33	513	1.0e-68	254	COG4383	Mu-like prophage protein gp29	517
647804953	563	34.64	21	551	2	509	6.0e-102	365	COG4373	Mu-like prophage FluMu protein gp28	509
647804971	217	28.26	40	216	31	212	2.0e-21	95.5	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
647804972	227	33.19	1	227	1	226	4.0e-30	125	COG2135	Putative SOS response-associated peptidase YedK	226
647804976	207	29.3	1	205	2	213	4.0e-27	114	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
647804983	217	36.53	7	173	1	167	9.0e-41	160	COG2518	Protein-L-isoaspartate O-methyltransferase	209
647804984	494	26.04	62	461	52	457	3.0e-30	126	COG1538	Outer membrane protein TolC	457
647804986	488	51.43	3	482	1	486	0.0e+00	561	COG1492	Cobyric acid synthase	486
647804988	230	43.51	44	174	1	131	6.0e-38	150	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
647804990	248	34.12	2	230	20	274	2.0e-43	169	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
647804991	614	36.41	4	576	1	567	8.0e-118	417	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647804993	405	34.67	13	400	7	382	2.0e-70	259	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
647804995	371	33.88	7	366	3	355	7.0e-69	254	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
647804996	265	34.09	2	261	1	255	2.0e-36	145	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647804998	488	37.18	146	467	66	408	3.0e-43	169	COG0840	Methyl-accepting chemotaxis protein	408
647804999	300	42.99	9	300	7	324	5.0e-70	257	COG3588	Fructose-bisphosphate aldolase class 1	332
647805002	547	58.64	3	545	2	531	0.0e+00	838	COG0504	CTP synthase (UTP-ammonia lyase)	533
647805003	121	37.97	1	78	1	79	1.0e-10	58.7	COG1314	Preprotein translocase subunit SecG	86
647805007	437	58.35	1	436	1	430	0.0e+00	626	COG0104	Adenylosuccinate synthase	430
647805010	223	28.06	11	196	3	198	2.0e-21	96.1	COG1564	Thiamine pyrophosphokinase	212
647805011	325	21.14	14	307	9	291	5.0e-06	45.6	COG5006	Threonine/homoserine efflux transporter RhtA	292
647805012	299	32.06	1	262	2	263	4.0e-30	125	COG4757	Predicted alpha/beta hydrolase	281
647805013	184	21.79	1	179	8	185	9.0e-08	50.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647805014	457	48.76	171	453	1	262	8.0e-81	294	COG1760	L-serine deaminase	262
647805015	235	33.8	7	214	4	205	6.0e-24	104	COG0625	Glutathione S-transferase	211
647805017	262	51.71	6	237	1	226	8.0e-68	250	COG0120	Ribose 5-phosphate isomerase	227
647805019	145	50	1	142	6	145	3.0e-41	160	COG4125	Uncharacterized membrane protein	149
647805021	451	36.87	1	444	1	453	1.0e-115	410	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
647805022	386	26.69	90	366	7	281	3.0e-41	162	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
647805023	294	33.11	3	291	2	291	2.0e-37	149	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
647805025	498	42.46	27	380	12	341	2.0e-67	250	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
647805028	222	31.6	6	210	2	213	5.0e-28	118	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
647805030	107	37.38	1	106	1	102	4.0e-16	76.6	COG0633	Ferredoxin	102
647805032	156	18.31	13	148	12	140	1.0e-07	49.1	COG3153	Predicted N-acetyltransferase YhbS	171
647805033	420	51.65	1	420	1	423	0.0e+00	521	COG0151	Phosphoribosylamine-glycine ligase	428
647805034	502	42.76	13	471	2	430	3.0e-119	422	COG1570	Exonuclease VII, large subunit	440
647805037	388	45.9	67	383	12	340	1.0e-95	343	COG0552	Signal recognition particle GTPase	340
647805040	212	36.51	21	208	2	177	1.0e-31	129	COG2917	Intracellular septation protein A	180
647805045	395	45.48	1	395	2	396	7.0e-122	430	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
647805046	367	29.18	75	341	4	277	3.0e-42	165	COG1469	GTP cyclohydrolase FolE2	289
647805048	482	35.28	3	482	2	488	2.0e-76	280	COG0168	Trk-type K+ transport system, membrane component	499
647805049	412	41.23	1	409	1	447	1.0e-113	403	COG0527	Aspartokinase	447
647805050	746	46.17	13	746	5	746	0.0e+00	691	COG3605	Signal transduction protein containing GAF and PtsI domains	756
647805051	570	36.09	14	565	2	550	0.0e+00	492	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
647805052	207	35.15	1	193	1	200	1.0e-36	146	COG0625	Glutathione S-transferase	211
647805054	396	33.33	18	383	16	383	2.0e-57	216	COG3853	Uncharacterized conserved protein YaaN involved in tellurite resistance	386
647805056	410	43.64	63	290	4	239	3.0e-60	226	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
647805057	150	53.52	6	147	11	152	2.0e-42	165	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
647805058	274	28.36	1	268	1	269	3.0e-19	88.9	COG3570	Streptomycin 6-kinase	274
647805059	193	25.33	2	151	11	160	3.0e-08	52.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647805060	97	22.47	1	84	3	91	1.0e-05	41.4	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
647805061	200	55.19	11	186	1	183	3.0e-66	244	COG2818	3-methyladenine DNA glycosylase Tag	188
647805063	389	29.79	6	389	5	383	2.0e-70	259	COG0006	Xaa-Pro aminopeptidase	384
647805064	230	30.2	1	230	7	250	2.0e-27	116	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
647805066	95	47.37	1	95	1	95	2.0e-22	97.2	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
647805067	495	49	1	493	1	475	0.0e+00	474	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
647805071	55	46.81	7	53	4	50	7.0e-08	49.1	COG0267	Ribosomal protein L33	50
647805074	259	40.86	5	257	3	228	9.0e-30	124	COG0670	Integral membrane protein, interacts with FtsH	233
647805076	305	29	4	286	1	297	6.0e-27	115	COG0583	DNA-binding transcriptional regulator, LysR family	297
647805077	324	37.99	1	318	1	326	4.0e-57	215	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647805078	124	18.97	8	120	1	116	2.0e-06	44.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
647805079	264	33.33	8	262	3	260	2.0e-49	189	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
647805080	446	35.43	1	423	1	413	7.0e-71	261	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
647805081	429	32.8	26	395	17	383	6.0e-75	275	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
647805082	462	41.48	19	462	3	448	1.0e-110	393	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
647805083	195	36.46	13	193	3	191	2.0e-27	116	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
647805084	279	25.22	19	222	25	238	2.0e-07	50.4	COG3751	Proline 4-hydroxylase (includes Rps23 Pro-64 3,4-dihydroxylase Tpa1), contains SM-20 domain	252
647805086	281	52.22	12	281	1	266	8.0e-96	343	COG1692	Calcineurin-like phosphoesterase	266
647805089	592	20.97	121	592	54	458	9.0e-29	122	COG0471	Di- and tricarboxylate transporter	461
647805090	154	31.62	6	139	2	136	2.0e-15	75.5	COG3187	Heat shock protein HslJ	142
647805091	156	48	1	147	10	159	7.0e-41	159	COG3236	Predicted NAD-dependent protein-ADP-ribosyltransferase YbiA, DUF1768 family	162
647805092	557	67.34	10	553	6	547	0.0e+00	796	COG3573	Predicted oxidoreductase	552
647805093	591	19.78	132	591	73	458	1.0e-28	121	COG0471	Di- and tricarboxylate transporter	461
647805096	246	61.83	1	240	1	241	3.0e-96	344	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
647805099	297	27.95	9	295	5	297	9.0e-18	84.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
647805100	209	51.49	10	209	1	201	5.0e-50	190	COG1279	Arginine exporter protein ArgO	202
647805101	313	38.27	18	292	6	276	5.0e-62	231	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
647805102	529	36.07	8	519	4	502	1.0e-100	360	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
647805104	150	32.82	5	135	2	132	9.0e-21	93	COG5502	Uncharacterized conserved protein, DUF2267 family	135
647805105	310	20	22	291	14	282	1.0e-05	44.1	COG5006	Threonine/homoserine efflux transporter RhtA	292
647805106	335	36.51	1	125	11	135	3.0e-20	92.8	COG5480	Uncharacterized membrane protein	147
647805107	196	20.62	1	193	4	197	3.0e-07	48.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647805108	402	20.1	1	373	52	463	7.0e-29	121	COG1292	Choline-glycine betaine transporter	537
647805109	485	46.85	9	480	1	471	0.0e+00	504	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647805110	551	54.06	1	536	6	541	0.0e+00	524	COG2303	Choline dehydrogenase or related flavoprotein	542
647805112	79	45.59	12	79	2	69	2.0e-10	57.2	COG2841	Uncharacterized conserved protein YdcH, DUF465 family	72
647805113	462	54.1	142	461	3	331	2.0e-110	392	COG3800	Predicted transcriptional regulator	332
647805114	397	19.9	1	392	3	391	3.0e-19	89.9	COG2814	Predicted arabinose efflux permease, MFS family	394
647805115	510	58.19	1	510	11	526	0.0e+00	715	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
647805124	676	54.79	1	676	1	644	0.0e+00	874	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
647805128	709	62.82	6	545	3	548	0.0e+00	730	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
647805130	162	19.57	16	140	1	138	4.0e-06	44.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
647805132	181	44.24	9	170	4	168	2.0e-34	138	COG1247	L-amino acid N-acyltransferase YncA	169
647805133	235	25.86	51	221	1	173	7.0e-20	91.2	COG1076	DnaJ-domain-containing proteins 1	174
647805135	299	26.82	5	298	1	297	6.0e-24	105	COG0583	DNA-binding transcriptional regulator, LysR family	297
647805139	548	29.31	49	479	1	442	1.0e-72	267	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
647805141	380	29.81	1	359	8	349	3.0e-40	159	COG0628	Predicted PurR-regulated permease PerM	355
647805143	589	36.9	188	438	97	335	3.0e-43	170	COG0642	Signal transduction histidine kinase	336
647805144	451	41.28	1	438	1	498	0.0e+00	468	COG0442	Prolyl-tRNA synthetase	500
647805145	281	61.87	1	278	2	277	1.0e-121	429	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
647805151	427	38.73	6	427	1	408	8.0e-91	327	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
647805152	227	45.5	6	226	2	222	2.0e-68	252	COG1136	ABC-type lipoprotein export system, ATPase component	226
647805155	304	46.69	10	294	2	287	2.0e-77	282	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
647805156	389	45.22	1	380	7	390	5.0e-109	388	COG0372	Citrate synthase	390
647805157	503	34.86	13	488	1	452	1.0e-104	373	COG2079	2-methylcitrate dehydratase PrpD	453
647805159	461	57.53	134	461	1	332	3.0e-114	405	COG3800	Predicted transcriptional regulator	332
647805160	385	41.49	1	385	9	382	1.0e-62	233	COG3448	CBS-domain-containing membrane protein	382
647805162	293	27.7	7	291	1	296	8.0e-34	137	COG0583	DNA-binding transcriptional regulator, LysR family	297
647805163	380	27.65	13	380	23	384	1.0e-36	147	COG1680	CubicO group peptidase, beta-lactamase class C family	390
647805165	183	36.46	1	182	3	193	8.0e-27	113	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
647805167	397	26.67	3	389	9	373	3.0e-51	196	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
647805168	436	28.68	35	397	1	369	3.0e-50	193	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647805169	455	36.6	12	454	3	443	2.0e-103	369	COG0174	Glutamine synthetase	443
647805170	226	28.92	1	192	2	194	8.0e-31	127	COG0518	GMP synthase - Glutamine amidotransferase domain	198
647805171	439	37.16	7	429	16	434	6.0e-100	358	COG0174	Glutamine synthetase	443
647805178	68	58.82	1	68	1	67	1.0e-20	91	COG1278	Cold shock protein, CspA family	67
647805179	210	25	6	209	5	197	5.0e-15	74.5	COG3916	N-acyl-L-homoserine lactone synthetase	209
647805180	588	30.6	122	433	32	336	1.0e-38	154	COG0642	Signal transduction histidine kinase	336
647805182	600	39.62	23	595	3	567	0.0e+00	464	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647805183	136	35.2	6	127	5	127	8.0e-17	79.6	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
647805184	628	33.33	19	577	5	533	2.0e-98	353	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647805185	308	33.22	22	293	18	304	6.0e-46	178	COG0657	Acetyl esterase/lipase	312
647805189	545	44.51	1	529	1	539	0.0e+00	589	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
647805190	271	38.08	3	259	19	278	2.0e-54	206	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647805191	318	38.92	5	318	2	317	2.0e-74	272	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647805192	528	26.65	12	525	1	556	1.0e-80	294	COG0747	ABC-type transport system, periplasmic component	556
647805194	156	61.38	1	145	1	145	7.0e-59	219	COG1490	D-Tyr-tRNAtyr deacylase	145
647805196	448	32.58	58	362	6	315	1.0e-60	227	COG4260	Membrane protease subunit, stomatin/prohibitin family, contains C-terminal Zn-ribbon domain	345
647805197	395	33.85	11	392	28	407	2.0e-70	259	COG2124	Cytochrome P450	411
647805198	583	34.39	7	574	2	599	1.0e-93	337	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
647805199	417	36.72	10	417	4	463	9.0e-89	320	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
647805200	334	35.63	1	332	1	331	1.0e-82	300	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647805202	225	27.4	1	219	1	177	2.0e-23	102	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647805203	458	42.32	54	450	7	378	2.0e-92	333	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647805205	490	36.77	1	477	28	513	9.0e-111	394	COG0513	Superfamily II DNA and RNA helicase	513
647805207	535	53.24	10	532	4	527	0.0e+00	728	COG4108	Peptide chain release factor RF-3	528
647805208	97	26.92	1	97	1	104	9.0e-07	45.3	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
647805211	259	33.21	3	255	1	251	4.0e-29	121	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647805212	372	33.13	111	270	6	164	6.0e-27	115	COG4335	3-methyladenine DNA glycosylase AlkC	167
647805213	400	38.74	46	400	3	352	7.0e-90	324	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
647805215	234	39.82	6	224	4	221	2.0e-44	172	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
647805218	162	27.17	1	92	1	89	8.0e-10	56.5	COG1826	Sec-independent protein translocase protein TatA	94
647805219	296	37.77	5	282	1	247	1.0e-47	183	COG0805	Sec-independent protein secretion pathway component TatC	255
647805220	369	50	73	333	11	272	3.0e-91	329	COG2607	Predicted ATPase, AAA+ superfamily	287
647805221	454	23.89	182	394	3	249	3.0e-13	70.2	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
647805222	215	50.5	16	214	10	208	1.0e-57	216	COG2518	Protein-L-isoaspartate O-methyltransferase	209
647805223	260	39.69	1	257	1	248	1.0e-69	256	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
647805224	215	28.18	1	215	4	220	1.0e-22	100	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647805227	506	48.46	1	482	4	467	0.0e+00	542	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
647805230	454	56.5	2	444	4	447	0.0e+00	590	COG1066	Predicted ATP-dependent serine protease	456
647805233	252	49.41	1	250	4	255	1.0e-83	302	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
647805234	260	42.64	3	260	8	265	1.0e-53	203	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
647805235	345	42.46	1	343	2	358	6.0e-86	311	COG0787	Alanine racemase	360
647805236	505	39.79	29	495	1	434	4.0e-123	435	COG0305	Replicative DNA helicase	435
647805237	226	35.47	17	217	7	201	2.0e-38	152	COG0461	Orotate phosphoribosyltransferase	201
647805238	346	60.87	1	345	1	343	0.0e+00	513	COG0418	Dihydroorotase	344
647805245	318	26.14	10	298	1	281	8.0e-33	134	COG0714	MoxR-like ATPase	329
647805246	429	43.72	10	406	6	392	2.0e-82	299	COG3552	Uncharacterized conserved protein, contains von Willebrand factor type A (vWA) domain	395
647805247	337	39.55	24	334	7	259	1.0e-44	174	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
647805250	161	57.52	1	153	1	153	8.0e-57	212	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
647805251	618	37.02	7	603	1	557	2.0e-122	433	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
647805253	261	37.01	1	261	1	280	1.0e-48	186	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
647805254	143	66.91	1	139	34	172	4.0e-53	200	COG0290	Translation initiation factor IF-3	176
647805256	290	27.68	30	288	9	266	3.0e-40	158	COG1018	Ferredoxin-NADP reductase	266
647805258	253	36.48	14	248	4	247	6.0e-50	191	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
647805259	555	36.35	1	545	1	509	5.0e-129	455	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
647805261	272	45.49	22	254	1	231	2.0e-61	229	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
647805263	115	38.18	1	109	46	154	5.0e-14	69.7	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647805267	509	27.94	5	272	7	257	5.0e-19	89.4	COG4584	Transposase	278
647805268	263	39.83	13	244	13	247	7.0e-43	167	COG1484	DNA replication protein DnaC	254
647805273	387	34.37	4	382	3	382	3.0e-69	256	COG3214	Uncharacterized conserved protein YcaQ, contains winged helix DNA-binding domain	400
647805274	904	33.33	1	386	1	396	5.0e-87	316	COG0004	Ammonia channel protein AmtB	409
647805276	197	20.92	1	194	2	196	7.0e-06	43.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647805277	327	37.19	8	327	6	322	1.0e-64	240	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
647805278	310	31.91	1	307	1	303	1.0e-40	160	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647805279	254	20.97	1	248	5	210	4.0e-09	55.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647805280	421	23.02	15	416	17	431	8.0e-42	165	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
647805283	285	25.62	15	242	6	241	2.0e-30	126	COG0338	Site-specific DNA-adenine methylase	274
647805284	266	26.35	12	266	6	281	8.0e-18	84.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647805286	318	44.35	42	288	9	254	3.0e-61	229	COG3739	Uncharacterized membrane protein YoaT, DUF817 family	263
647805289	251	29.64	3	251	25	276	6.0e-50	190	COG0061	NAD kinase	281
647805290	473	32.15	5	463	3	468	8.0e-75	274	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
647805291	69	41.54	1	65	3	67	8.0e-08	48.8	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
647805292	630	37.57	44	600	1	522	0.0e+00	522	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
647805293	759	54.5	7	436	15	432	0.0e+00	544	COG0281	Malic enzyme	432
647805295	139	42.11	6	138	2	134	4.0e-32	130	COG0295	Cytidine deaminase	134
647805296	438	46.14	1	437	2	434	3.0e-115	408	COG0213	Thymidine phosphorylase	435
647805297	404	50.61	1	403	1	393	3.0e-126	445	COG1015	Phosphopentomutase	397
647805298	210	61.84	5	210	4	210	1.0e-82	298	COG0035	Uracil phosphoribosyltransferase	210
647805301	336	34.49	23	334	20	325	9.0e-59	221	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647805303	362	39.73	1	362	4	359	2.0e-92	332	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
647805304	391	37.37	4	389	8	394	1.0e-64	240	COG2814	Predicted arabinose efflux permease, MFS family	394
647805305	223	29.22	10	219	9	249	1.0e-17	83.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647805307	293	29.19	1	293	1	292	2.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
647805311	184	46.82	10	181	12	183	6.0e-46	177	COG3911	Predicted ATPase	183
647805312	733	43.61	325	627	2	305	2.0e-82	300	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
647805313	403	36.82	1	403	1	392	1.0e-70	260	COG0183	Acetyl-CoA acetyltransferase	392
647805314	225	27.86	16	210	1	198	4.0e-25	107	COG0625	Glutathione S-transferase	211
647805315	387	41.51	14	387	5	386	8.0e-85	307	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647805317	593	34.29	79	456	43	393	3.0e-67	250	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647805318	133	39.29	7	116	2	111	5.0e-13	66.7	COG0789	DNA-binding transcriptional regulator, MerR family	124
647805319	122	29.09	6	113	1	109	1.0e-09	55.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
647805320	140	29.5	1	139	4	139	1.0e-20	92.4	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
647805321	172	21.52	13	169	4	141	8.0e-13	67	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
647805322	441	30.89	1	432	7	442	5.0e-53	202	COG0534	Na+-driven multidrug efflux pump	455
647805324	352	44.62	43	348	1	308	8.0e-79	287	COG0167	Dihydroorotate dehydrogenase	310
647805325	112	53.15	2	111	5	115	1.0e-26	111	COG3502	Uncharacterized conserved protein, DUF952 family	115
647805326	526	35.4	1	515	1	501	2.0e-89	323	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
647805329	156	36.44	23	140	5	122	5.0e-11	60.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
647805331	298	35.34	10	257	9	250	2.0e-30	126	COG2603	tRNA 2-selenouridine synthase SelU, contains rhodanese domain	334
647805332	720	26.72	7	371	1	391	5.0e-45	176	COG1252	NADH dehydrogenase, FAD-containing subunit	405
647805333	125	32.99	1	97	2	98	9.0e-19	85.7	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
647805334	89	37.5	1	88	2	89	2.0e-07	47.4	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
647805335	165	37.11	7	165	1	158	1.0e-30	126	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
647805336	546	33.33	1	515	1	500	1.0e-59	224	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
647805338	953	40.94	3	573	1	563	3.0e-117	416	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
647805339	157	25.23	44	154	7	108	2.0e-10	58.8	COG0607	Rhodanese-related sulfurtransferase	110
647805340	277	27.31	1	257	11	279	1.0e-19	90.8	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
647805342	630	36.44	14	612	28	639	0.0e+00	467	COG2943	Membrane glycosyltransferase	736
647805343	508	43.88	4	507	1	527	0.0e+00	470	COG3131	Periplasmic glucans biosynthesis protein	534
647805344	425	25.63	30	421	16	378	6.0e-31	128	COG4645	Uncharacterized protein	410
647805346	399	48.16	13	391	4	378	1.0e-113	403	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
647805347	537	32.35	7	532	4	534	6.0e-99	354	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
647805348	164	17.36	39	158	16	136	4.0e-06	44.5	COG3439	Uncharacterized conserved protein, DUF302 family	137
647805349	335	43.59	22	332	9	320	6.0e-84	304	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
647805350	218	67.86	19	214	2	197	3.0e-79	287	COG0740	ATP-dependent protease ClpP, protease subunit	200
647805351	395	75.3	16	349	1	335	0.0e+00	615	COG1219	ATP-dependent protease Clp, ATPase subunit	408
647805353	237	28.89	17	237	16	236	4.0e-29	121	COG0412	Dienelactone hydrolase	236
647805354	123	32.8	1	116	2	126	5.0e-17	79.9	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
647805356	128	47.15	12	128	2	118	1.0e-24	105	COG3761	NADH:ubiquinone oxidoreductase 17.2 kD subunit	118
647805358	145	31.13	3	145	6	155	6.0e-17	80.1	COG4765	Uncharacterized protein	164
647805359	210	52.13	1	184	21	206	3.0e-64	238	COG2360	Leu/Phe-tRNA-protein transferase	221
647805360	449	63.25	1	447	1	449	0.0e+00	613	COG0439	Biotin carboxylase	449
647805361	167	40.65	13	167	1	139	3.0e-21	94.7	COG0511	Biotin carboxyl carrier protein	140
647805363	251	50	21	251	4	237	7.0e-72	263	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
647805364	251	40.96	1	249	2	250	6.0e-75	273	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
647805365	399	28.69	16	372	2	305	3.0e-36	146	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
647805366	340	31.16	1	337	3	295	4.0e-46	178	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
647805367	448	27.15	35	413	1	360	8.0e-39	154	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
647805368	443	25.42	161	433	23	315	1.0e-16	81.5	COG3800	Predicted transcriptional regulator	332
647805371	896	21.14	1	521	2	487	3.0e-45	177	COG0591	Na+/proline symporter	493
647805373	142	45.8	1	131	1	130	2.0e-31	128	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
647805377	88	55.42	6	88	3	85	3.0e-15	73.8	COG3750	Uncharacterized conserved protein, UPF0335 family	85
647805379	434	34.77	3	325	1	310	4.0e-82	298	COG0167	Dihydroorotate dehydrogenase	310
647805380	204	24.32	2	184	1	179	6.0e-12	64.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647805381	416	26.42	14	414	4	409	1.0e-49	190	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647805382	484	34.08	1	445	1	430	1.0e-114	407	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
647805383	282	48.64	26	282	1	248	5.0e-86	310	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
647805384	305	32.22	64	302	28	255	1.0e-35	143	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
647805385	281	34.5	25	280	3	258	3.0e-44	172	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
647805386	328	24.92	5	319	12	322	2.0e-31	129	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
647805388	166	35.33	17	161	10	159	2.0e-25	108	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
647805389	222	44.33	7	209	3	169	4.0e-48	184	COG0563	Adenylate kinase or related kinase	178
647805390	652	43.11	70	634	1	528	0.0e+00	648	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
647805391	294	23.23	6	253	7	250	3.0e-21	96.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647805392	852	21.61	191	616	36	468	5.0e-09	56.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
647805394	461	43.89	136	429	88	406	1.0e-47	184	COG0840	Methyl-accepting chemotaxis protein	408
647805397	307	25.52	15	246	2	237	3.0e-19	89.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647805398	442	26.23	126	432	2	320	9.0e-33	134	COG0642	Signal transduction histidine kinase	336
647805400	309	24.92	3	298	2	297	7.0e-30	124	COG0583	DNA-binding transcriptional regulator, LysR family	297
647805401	322	22.54	81	293	15	209	1.0e-14	74.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647805402	348	62.72	5	340	1	337	7.0e-127	447	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
647805403	201	49.74	5	193	1	187	2.0e-62	231	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
647805404	385	40.76	4	369	1	361	3.0e-89	322	COG0349	Ribonuclease D	361
647805406	136	50.38	4	135	10	142	1.0e-37	148	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
647805408	232	48.21	3	225	4	227	1.0e-65	242	COG5012	Methanogenic corrinoid protein MtbC1	227
647805409	360	43.1	47	336	8	292	3.0e-78	285	COG1533	DNA repair photolyase	297
647805410	344	32.17	3	299	1	311	6.0e-65	241	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
647805411	635	22.73	105	600	31	528	2.0e-28	121	COG2898	Lysylphosphatidylglycerol synthetase, C-terminal domain, DUF2156 family	538
647805412	105	58.25	1	100	1	101	3.0e-21	93.2	COG5467	Uncharacterized protein	104
647805413	253	53.75	1	239	1	237	4.0e-86	311	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
647805414	76	56.41	1	75	2	79	2.0e-21	94.1	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
647805415	222	52.23	1	215	3	226	2.0e-84	305	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
647805417	600	34.62	33	590	5	600	3.0e-102	366	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
647805418	416	34.27	1	414	1	461	1.0e-84	307	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
647805419	229	31.47	1	197	1	196	1.0e-30	127	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
647805420	952	47.94	272	683	73	485	2.0e-112	400	COG1530	Ribonuclease G or E	487
647805422	292	47.71	54	270	10	220	1.0e-31	130	COG0785	Cytochrome c biogenesis protein CcdA	220
647805424	449	24.17	2	449	6	410	2.0e-45	176	COG2124	Cytochrome P450	411
647805428	465	66.23	2	463	1	462	0.0e+00	748	COG0114	Fumarate hydratase class II	462
647805431	160	44.59	5	160	6	156	9.0e-37	146	COG3814	Uncharacterized protein	157
647805432	428	43.43	9	181	2	176	3.0e-32	133	COG2059	Chromate transport protein ChrA	195
647805434	243	35.39	1	241	1	240	8.0e-30	123	COG2186	DNA-binding transcriptional regulator, FadR family	241
647805435	257	38.65	19	256	32	282	1.0e-33	136	COG5486	Predicted metal-binding membrane protein	283
647805436	214	39.51	13	213	5	206	6.0e-50	190	COG5588	Uncharacterized protein	207
647805437	371	29.78	11	365	2	364	1.0e-53	203	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
647805438	331	32.93	2	328	1	325	4.0e-51	195	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647805439	427	27.42	23	427	3	403	3.0e-60	226	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
647805440	474	39.15	6	471	3	461	1.0e-108	386	COG0415	Deoxyribodipyrimidine photolyase	461
647805443	344	49.04	3	312	1	300	1.0e-99	356	COG0031	Cysteine synthase	300
647805444	836	27.12	55	812	68	835	5.0e-101	362	COG3264	Small-conductance mechanosensitive channel	835
647805446	275	27.67	5	257	2	246	4.0e-41	162	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
647805447	267	36.02	2	260	1	255	4.0e-44	171	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647805449	207	31.28	11	200	5	192	3.0e-26	111	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
647805450	373	51.77	3	369	2	360	1.0e-115	409	COG0337	3-dehydroquinate synthetase	360
647805451	196	42.26	21	188	2	168	9.0e-50	190	COG0703	Shikimate kinase	172
647805454	317	42.35	6	310	4	300	6.0e-79	287	COG4974	Site-specific recombinase XerD	300
647805455	437	45.56	11	435	1	416	4.0e-127	448	COG4536	Mg2+ and Co2+ transporter CorB, contains DUF21, CBS pair, and CorC-HlyC domains	423
647805456	805	32.16	417	805	1	379	3.0e-84	307	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
647805457	177	39.43	3	177	1	167	7.0e-35	140	COG0629	Single-stranded DNA-binding protein	167
647805461	378	36.89	19	325	54	338	1.0e-64	240	COG1858	Cytochrome c peroxidase	364
647805463	695	46.48	11	331	1	315	3.0e-103	369	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
647805465	350	31.27	1	350	1	316	1.0e-59	223	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647805466	555	25.17	24	554	2	553	2.0e-54	207	COG0747	ABC-type transport system, periplasmic component	556
647805467	178	30.77	68	171	23	126	1.0e-12	66	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647805468	287	36.33	12	277	6	282	8.0e-62	230	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
647805469	249	60.26	16	249	5	238	6.0e-89	320	COG0528	Uridylate kinase	238
647805470	187	48.04	10	187	9	187	1.0e-54	206	COG0233	Ribosome recycling factor	187
647805471	256	55.9	26	254	17	245	2.0e-85	308	COG0020	Undecaprenyl pyrophosphate synthase	245
647805472	261	28.08	13	256	1	260	2.0e-24	106	COG0575	CDP-diglyceride synthetase	265
647805473	390	46.79	1	388	1	383	1.0e-124	440	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
647805474	450	32.73	13	450	1	373	3.0e-45	176	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
647805476	778	31.97	3	778	1	766	0.0e+00	479	COG4775	Outer membrane protein assembly factor BamA	766
647805478	160	52.03	9	155	1	145	4.0e-42	163	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
647805479	261	50.97	1	256	3	259	1.0e-86	313	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
647805480	262	38.2	2	257	7	273	2.0e-44	172	COG3494	Uncharacterized conserved protein, DUF1009 family	279
647805481	403	41.39	18	402	2	381	5.0e-98	351	COG0763	Lipid A disaccharide synthetase	381
647805482	381	42.98	18	377	1	352	4.0e-111	394	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
647805484	239	40.17	1	224	1	228	1.0e-54	206	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647805485	739	48.72	1	737	2	667	0.0e+00	813	COG0272	NAD-dependent DNA ligase	667
647805486	696	49.7	6	668	3	664	0.0e+00	775	COG1200	RecG-like helicase	677
647805488	150	25.76	10	140	6	137	5.0e-20	90.4	COG0822	NifU homolog involved in Fe-S cluster formation	150
647805489	129	59.63	9	116	2	110	5.0e-41	159	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
647805492	446	56.05	1	445	2	437	0.0e+00	622	COG1206	Folate-dependent tRNA-U54 methylase TrmFO/GidA	439
647805493	140	35.34	25	140	26	140	4.0e-19	87	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
647805494	284	47.5	4	283	3	280	5.0e-80	291	COG0421	Spermidine synthase	282
647805497	471	28.17	16	462	1	453	8.0e-66	244	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
647805498	152	55.41	1	147	1	148	1.0e-52	198	COG0102	Ribosomal protein L13	148
647805499	161	57.81	34	161	3	130	2.0e-45	174	COG0103	Ribosomal protein S9	130
647805500	716	37.07	340	689	34	408	1.0e-50	195	COG0840	Methyl-accepting chemotaxis protein	408
647805501	205	23.62	1	199	3	201	5.0e-09	54.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647805502	289	55.56	20	269	19	270	8.0e-90	323	COG2326	Polyphosphate kinase 2, PPK2 family	270
647805504	312	51.82	1	302	1	303	3.0e-126	445	COG1897	Homoserine trans-succinylase	307
647805510	520	67.4	202	520	1	315	0.0e+00	544	COG0519	GMP synthase, PP-ATPase domain/subunit	315
647805511	514	50.1	3	513	12	525	0.0e+00	608	COG5598	Trimethylamine:corrinoid methyltransferase	526
647805514	316	60.2	10	308	9	306	0.0e+00	471	COG0320	Lipoate synthase	306
647805515	380	36.39	6	380	11	390	4.0e-74	272	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
647805516	178	55.11	1	176	1	175	7.0e-60	223	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
647805517	148	46.62	1	148	1	144	2.0e-43	168	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
647805518	159	53.9	4	156	11	162	1.0e-39	155	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
647805519	165	33.77	5	155	18	159	2.0e-18	85.3	COG1267	Phosphatidylglycerophosphatase A	160
647805520	382	57.96	226	382	1	157	3.0e-60	225	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
647805521	328	41.61	2	320	1	319	3.0e-83	302	COG0042	tRNA-dihydrouridine synthase	323
647805522	362	37.28	13	354	11	352	4.0e-77	281	COG3852	Signal transduction histidine kinase, nitrogen specific	363
647805523	459	35.39	1	457	3	463	1.0e-93	337	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
647805524	759	38.83	33	741	8	707	0.0e+00	538	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
647805525	472	44.3	1	449	4	456	0.0e+00	469	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
647805526	458	33.19	1	231	1	225	2.0e-38	153	COG0569	Trk K+ transport system, NAD-binding component	225
647805527	529	25.55	33	528	8	487	2.0e-32	133	COG0168	Trk-type K+ transport system, membrane component	499
647805528	79	63.01	6	78	5	77	1.0e-27	115	COG1923	sRNA-binding regulator protein Hfq	77
647805529	423	47.77	20	400	12	387	2.0e-101	362	COG2262	50S ribosomal subunit-associated GTPase HflX	411
647805530	823	29.06	6	807	3	757	5.0e-103	369	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
647805531	290	47.9	2	287	1	286	3.0e-85	308	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
647805532	190	23.26	23	186	11	182	1.0e-14	73.1	COG2930	Lipid-binding SYLF domain	227
647805533	332	60.49	8	330	5	327	0.0e+00	483	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
647805535	1151	45.22	2	1140	8	1136	0.0e+00	1270	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
647805536	407	23.32	16	396	14	386	8.0e-17	81.8	COG2814	Predicted arabinose efflux permease, MFS family	394
647805537	233	39.25	8	219	6	219	3.0e-54	205	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
647805538	502	26.72	14	502	8	527	2.0e-70	260	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647805539	209	26.36	26	134	1	110	3.0e-08	51.9	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
647805541	608	23.73	7	605	6	556	3.0e-66	246	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
647805542	257	41.06	1	255	1	251	3.0e-46	178	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647805543	342	22.62	3	338	10	297	2.0e-28	120	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
647805544	234	41.04	17	228	2	211	6.0e-56	210	COG2928	Uncharacterized membrane protein	222
647805545	302	60.2	4	302	11	309	2.0e-105	375	COG2313	Pseudouridine-5'-phosphate glycosidase (pseudoU degradation)	310
647805546	321	26.6	30	316	1	289	2.0e-21	96.8	COG0524	Sugar or nucleoside kinase, ribokinase family	311
647805547	210	31.55	9	208	4	205	5.0e-24	104	COG0352	Thiamine monophosphate synthase	211
647805549	249	41.28	8	242	5	234	3.0e-59	221	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
647805550	381	34.8	33	371	3	315	1.0e-44	174	COG1612	Heme A synthase	323
647805551	489	40.28	1	485	4	497	0.0e+00	468	COG2317	Zn-dependent carboxypeptidase, M32 family	497
647805553	928	50.06	33	920	2	804	0.0e+00	954	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
647805554	89	56.18	1	89	2	90	3.0e-29	119	COG5425	Usg protein (tryptophan operon, function unknown)	90
647805555	223	30.43	1	223	1	230	5.0e-37	147	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
647805556	157	29.13	30	153	11	137	2.0e-15	75.3	COG0824	Acyl-CoA thioesterase FadM	137
647805560	164	25.89	35	146	7	118	2.0e-08	51.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
647805562	412	22.72	10	412	4	408	3.0e-41	163	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647805564	441	29.77	99	441	10	308	4.0e-23	102	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
647805565	336	29.72	14	336	9	295	2.0e-38	153	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
647805566	237	47.48	3	237	1	237	1.0e-76	279	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
647805567	263	44	1	250	4	250	8.0e-77	280	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
647805568	397	28.83	17	334	1	322	2.0e-28	120	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
647805569	368	40.62	29	368	53	397	8.0e-74	271	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
647805570	334	47.04	12	331	5	325	1.0e-98	353	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
647805571	456	63.29	1	443	2	443	0.0e+00	677	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
647805573	298	41.89	3	298	2	290	3.0e-70	258	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
647805574	147	52.52	8	146	2	137	2.0e-49	187	COG0194	Guanylate kinase	191
647805576	173	49.71	1	173	2	174	2.0e-57	215	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
647805577	393	39.84	15	391	19	395	2.0e-98	352	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
647805579	346	22.62	4	331	22	318	3.0e-32	132	COG0226	ABC-type phosphate transport system, periplasmic component	318
647805580	492	42.02	187	491	11	310	2.0e-68	253	COG0573	ABC-type phosphate transport system, permease component	310
647805581	441	37.64	173	441	30	292	3.0e-61	229	COG0581	ABC-type phosphate transport system, permease component	292
647805582	255	66.67	1	255	1	253	7.0e-129	453	COG1117	ABC-type phosphate transport system, ATPase component	253
647805583	236	43.04	1	230	4	233	1.0e-40	159	COG0704	Phosphate uptake regulator	240
647805584	229	48.46	6	228	1	225	3.0e-59	221	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647805585	303	25.59	9	300	1	296	2.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
647805588	800	33.76	417	797	1	379	7.0e-82	299	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
647805589	295	23.24	10	283	6	277	5.0e-32	131	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
647805590	323	47.15	8	323	6	319	8.0e-89	320	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
647805592	143	30	1	143	4	152	2.0e-10	58.4	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
647805593	406	51.24	1	399	2	400	3.0e-130	458	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
647805596	426	27.74	28	410	17	399	3.0e-53	202	COG0719	Fe-S cluster assembly scaffold protein SufB	412
647805597	251	64.54	1	251	3	248	2.0e-100	358	COG0396	Fe-S cluster assembly ATPase SufC	251
647805599	104	58.1	1	103	1	105	9.0e-28	114	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
647805600	506	41.65	48	504	1	412	8.0e-124	437	COG0719	Fe-S cluster assembly scaffold protein SufB	412
647805601	347	41.78	2	346	1	382	5.0e-95	341	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
647805602	142	33.86	3	129	13	137	3.0e-23	101	COG1959	DNA-binding transcriptional regulator, IscR family	150
647805603	193	48.78	29	192	1	164	2.0e-49	188	COG1329	RNA polymerase-interacting regulator, CarD/CdnL/TRCF family	166
647805604	112	43.94	4	65	5	68	7.0e-08	49.4	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
647805605	124	50.53	1	94	1	94	7.0e-23	99.2	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
647805609	318	25.9	17	315	6	295	7.0e-39	154	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
647805612	606	35.18	19	606	6	597	0.0e+00	499	COG1164	Oligoendopeptidase F	598
647805614	89	27.06	1	77	36	120	2.0e-07	47.3	COG1734	RNA polymerase-binding transcription factor DksA	120
647805615	329	30.36	2	326	1	332	4.0e-45	175	COG0673	Predicted dehydrogenase	342
647805616	390	30.7	60	387	5	309	1.0e-46	180	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
647805618	298	39.37	7	289	60	335	2.0e-66	246	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
647805619	312	29.35	12	304	3	291	1.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
647805620	389	23.71	1	381	1	379	8.0e-56	211	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647805621	262	31.77	8	259	9	282	4.0e-23	101	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647805622	134	36.07	12	130	2	123	7.0e-19	86.2	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
647805623	240	44.49	1	236	3	226	1.0e-63	236	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
647805624	205	45.97	1	205	18	226	9.0e-53	199	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
647805625	277	30.07	1	271	1	293	2.0e-46	179	COG3246	Uncharacterized conserved protein, DUF849 family	298
647805626	357	32.84	11	341	1	335	4.0e-69	255	COG0015	Adenylosuccinate lyase	438
647805628	176	31.82	3	175	1	175	9.0e-22	96.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
647805630	478	24.95	1	465	1	447	1.0e-48	187	COG0527	Aspartokinase	447
647805632	428	36.59	3	420	13	447	8.0e-97	347	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
647805634	167	34.15	17	139	1	122	7.0e-12	63.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
647805636	1136	28.64	729	1124	13	424	2.0e-51	198	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
647805639	274	32.3	10	266	1	253	4.0e-42	165	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
647805640	322	34.34	36	322	1	295	5.0e-46	178	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
647805641	568	32.19	8	563	2	539	3.0e-72	266	COG1178	ABC-type Fe3+ transport system, permease component	540
647805642	347	41.76	1	340	1	329	4.0e-101	361	COG3839	ABC-type sugar transport system, ATPase component	338
647805644	170	31.44	1	170	7	198	3.0e-20	91.8	COG0406	Broad specificity phosphatase PhoE	208
647805647	697	26.58	89	364	1	295	1.0e-33	138	COG0515	Serine/threonine protein kinase	384
647805648	261	37.8	9	251	8	261	4.0e-47	181	COG0631	Serine/threonine protein phosphatase PrpC	262
647805649	221	24.17	4	212	7	214	4.0e-13	68.6	COG3913	Uncharacterized protein	227
647805650	1210	30.9	19	1209	10	1187	0.0e+00	671	COG3523	Type VI protein secretion system component VasK	1188
647805651	519	29.37	81	349	2	258	8.0e-43	168	COG3455	Type VI protein secretion system component VasF	262
647805652	444	34.68	1	440	1	444	3.0e-92	332	COG3522	Predicted component of the type VI protein secretion system	446
647805656	437	26.8	1	429	1	423	9.0e-48	184	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
647805658	174	48.73	5	161	3	158	5.0e-37	147	COG3516	Predicted component of the type VI protein secretion system	169
647805659	497	47.99	1	497	1	494	0.0e+00	586	COG3517	Predicted component of the type VI protein secretion system	495
647805660	165	27.38	1	163	1	162	1.0e-30	126	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
647805662	197	29.29	53	191	19	154	7.0e-09	54.2	COG3518	Predicted component of the type VI protein secretion system	157
647805663	642	32.35	1	642	1	621	8.0e-96	344	COG3519	Type VI protein secretion system component VasA	621
647805664	373	32.76	35	324	23	313	9.0e-42	164	COG3520	Predicted component of the type VI protein secretion system	335
647805665	907	37.42	12	904	1	783	0.0e+00	671	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
647805670	137	34.62	3	132	13	142	6.0e-25	106	COG5480	Uncharacterized membrane protein	147
647805673	208	22.9	1	203	4	216	3.0e-15	75.4	COG0811	Biopolymer transport protein ExbB/TolQ	216
647805678	554	28.23	160	283	25	148	5.0e-10	59.9	COG5616	TolB amino-terminal domain (function unknown)	152
647805680	133	32.79	1	116	1	122	2.0e-20	91.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
647805682	371	65.95	2	371	1	366	0.0e+00	543	COG1062	Zn-dependent alcohol dehydrogenase	366
647805683	505	54.9	14	503	7	478	0.0e+00	578	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
647805684	438	48.39	1	432	1	415	6.0e-121	427	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
647805685	644	64.14	4	644	3	649	0.0e+00	847	COG2766	Predicted Ser/Thr protein kinase	649
647805687	431	19.63	23	429	19	449	2.0e-16	80.6	COG1538	Outer membrane protein TolC	457
647805688	834	30.95	158	825	30	696	0.0e+00	474	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
647805689	390	21.62	18	368	14	341	2.0e-16	80.4	COG1566	Multidrug resistance efflux pump	352
647805692	276	30.28	116	252	2	138	5.0e-23	101	COG0394	Protein-tyrosine-phosphatase	139
647805693	332	50	5	329	5	331	5.0e-101	361	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
647805695	344	44.84	1	335	9	337	6.0e-76	277	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
647805696	123	36.64	1	122	1	131	1.0e-23	102	COG3791	Uncharacterized conserved protein	133
647805697	73	34.85	1	63	1	66	2.0e-13	66.9	COG0695	Glutaredoxin	80
647805698	140	58.16	1	137	1	141	1.0e-44	171	COG1780	Protein involved in ribonucleotide reduction	141
647805699	710	38.52	8	709	14	654	0.0e+00	650	COG0209	Ribonucleotide reductase alpha subunit	696
647805700	325	50	13	325	26	348	5.0e-99	354	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
647805702	682	37	2	545	4	550	2.0e-123	437	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
647805705	511	43.01	25	501	1	472	0.0e+00	464	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647805706	303	41.49	10	289	4	282	2.0e-52	199	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
647805707	302	32.08	9	299	6	293	2.0e-27	116	COG0583	DNA-binding transcriptional regulator, LysR family	297
647805708	379	46.23	4	379	8	391	2.0e-104	372	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
647805710	260	45.83	72	239	2	168	7.0e-40	157	COG1045	Serine acetyltransferase	194
647805711	220	28.3	10	219	9	219	1.0e-23	103	COG1802	DNA-binding transcriptional regulator, GntR family	230
647805712	233	31.34	11	224	9	223	2.0e-40	159	COG1451	Predicted metal-dependent hydrolase	223
647805714	176	46.15	38	176	3	144	8.0e-35	140	COG5458	Uncharacterized protein	144
647805715	230	28.51	1	228	1	209	2.0e-36	145	COG0040	ATP phosphoribosyltransferase	290
647805716	363	28.65	2	362	15	389	5.0e-26	112	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
647805717	504	34.23	14	496	6	429	3.0e-98	353	COG0124	Histidyl-tRNA synthetase	429
647805720	1166	43.72	4	1164	1	1139	0.0e+00	1156	COG0587	DNA polymerase III, alpha subunit	1139
647805722	290	41.77	5	248	18	262	2.0e-63	235	COG0005	Purine nucleoside phosphorylase	262
647805723	179	50	5	178	6	179	5.0e-47	180	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
647805724	160	54.17	16	158	38	181	7.0e-41	159	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
647805725	200	23.38	45	197	29	182	4.0e-10	58.1	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
647805726	480	37.25	34	480	15	457	4.0e-79	289	COG0277	FAD/FMN-containing dehydrogenase	459
647805727	196	32.97	6	189	1	184	3.0e-23	101	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
647805728	420	39.1	3	412	17	438	1.0e-86	313	COG0612	Predicted Zn-dependent peptidase	438
647805729	463	32.98	1	460	1	411	2.0e-89	323	COG0498	Threonine synthase	411
647805730	220	32.91	2	219	11	244	2.0e-33	135	COG3346	Cytochrome oxidase assembly protein ShyY1	252
647805731	271	39.05	58	267	10	209	4.0e-39	155	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
647805732	195	55.95	7	173	11	178	4.0e-60	224	COG3175	Cytochrome c oxidase assembly protein Cox11	195
647805734	313	46.1	1	307	1	301	7.0e-80	290	COG0109	Polyprenyltransferase (heme O synthase)	304
647805735	337	27.57	68	336	16	238	4.0e-49	188	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
647805736	473	41.36	21	470	8	453	6.0e-113	401	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
647805737	382	34.77	16	380	1	349	2.0e-75	276	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
647805738	884	46.61	1	582	1	554	0.0e+00	600	COG0550	DNA topoisomerase IA	570
647805740	141	28.45	14	116	11	124	1.0e-06	45.7	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
647805741	234	56.42	1	218	1	217	2.0e-80	291	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
647805742	208	60.19	3	206	6	211	2.0e-73	268	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
647805747	267	31.34	24	238	42	253	2.0e-26	112	COG3745	Flp pilus assembly protein CpaB	276
647805748	442	36.26	11	440	30	453	7.0e-88	318	COG4964	Flp pilus assembly protein, secretin CpaC	455
647805749	207	33.33	29	167	50	189	9.0e-23	100	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
647805750	414	24.75	107	403	55	341	2.0e-28	120	COG4963	Flp pilus assembly protein, ATPase CpaE	366
647805751	483	56.15	82	439	1	353	9.0e-122	430	COG4962	Pilus assembly protein, ATPase of CpaF family	355
647805752	322	26.27	8	322	1	309	9.0e-39	154	COG4965	Flp pilus assembly protein TadB	309
647805753	323	28.97	74	323	69	319	3.0e-19	89.5	COG2064	Pilus assembly protein TadC	320
647805758	142	30.53	10	140	9	137	2.0e-19	88.6	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
647805759	300	54.67	4	292	1	282	5.0e-108	384	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
647805760	120	31.58	24	117	2	96	2.0e-10	58	COG1605	Chorismate mutase	101
647805761	558	67.69	5	558	1	554	0.0e+00	896	COG2759	Formyltetrahydrofolate synthetase	554
647805764	637	55.93	8	598	1	594	0.0e+00	718	COG0465	ATP-dependent Zn proteases	596
647805765	426	34.58	1	208	1	211	3.0e-36	146	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
647805766	281	27.48	59	277	50	261	2.0e-20	92.8	COG1729	Periplasmic TolA-binding protein (function unknown)	262
647805767	166	34.27	5	160	10	187	3.0e-28	118	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
647805768	441	36.16	7	439	2	424	3.0e-80	292	COG0823	Periplasmic component of the Tol biopolymer transport system	425
647805770	162	43.18	15	146	2	132	1.0e-35	142	COG0848	Biopolymer transport protein ExbD	137
647805771	231	43.72	19	231	1	215	9.0e-47	180	COG0811	Biopolymer transport protein ExbB/TolQ	216
647805772	128	42.97	1	128	4	131	1.0e-31	128	COG0824	Acyl-CoA thioesterase FadM	137
647805774	125	23.66	6	98	6	91	2.0e-06	44.6	COG1694	NTP pyrophosphatase, house-cleaning of non-canonical NTPs	102
647805775	339	66.35	15	332	14	331	0.0e+00	495	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
647805776	229	40.89	1	225	1	200	1.0e-48	186	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
647805777	188	57.05	27	181	1	156	2.0e-50	191	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
647805780	289	33.88	1	289	1	299	2.0e-52	199	COG2264	Ribosomal protein L11 methylase PrmA	300
647805782	735	45.9	17	734	4	730	0.0e+00	711	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
647805783	217	48.05	1	217	8	238	2.0e-64	239	COG0176	Transaldolase	239
647805784	237	21.4	9	237	6	218	8.0e-14	70.7	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
647805785	311	37.3	10	311	2	300	3.0e-58	218	COG4974	Site-specific recombinase XerD	300
647805786	254	24	24	245	2	222	2.0e-28	119	COG1183	Phosphatidylserine synthase	234
647805788	278	44.05	20	271	1	247	1.0e-78	286	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
647805789	478	41.61	36	478	19	466	9.0e-118	417	COG3106	Predicted ATPase, YcjX-like family	467
647805790	154	23.78	2	125	1	140	9.0e-07	46.4	COG1247	L-amino acid N-acyltransferase YncA	169
647805791	326	32.26	20	326	31	340	3.0e-45	176	COG3768	Uncharacterized membrane protein YcjF, UPF0283 family	350
647805795	989	43.5	10	988	1	930	0.0e+00	1035	COG0060	Isoleucyl-tRNA synthetase	933
647805798	949	60.76	463	917	29	496	0.0e+00	690	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
647805800	119	55.37	1	119	9	129	2.0e-34	137	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
647805801	374	41.04	1	374	2	376	3.0e-93	335	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
647805803	352	44.11	24	348	2	329	2.0e-82	299	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
647805804	610	26.83	6	610	1	594	4.0e-62	232	COG0729	Outer membrane translocation and assembly module TamA	594
647805805	1335	20.06	7	1335	18	1278	1.0e-66	249	COG2911	Autotransporter translocation and assembly factor TamB	1278
647805806	327	20.74	13	317	55	376	4.0e-14	72.7	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
647805807	260	31.39	17	237	15	233	4.0e-35	141	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
647805809	2148	36.95	10	1073	1	1036	0.0e+00	719	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
647805810	349	25.59	9	299	8	286	2.0e-33	137	COG1216	Glycosyltransferase, GT2 family	305
647805812	236	39.41	32	227	26	226	9.0e-36	143	COG2977	4'-phosphopantetheinyl transferase EntD (siderophore biosynthesis)	228
647805815	280	21.53	8	216	4	208	3.0e-13	69.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
647805817	450	24.78	8	449	2	449	7.0e-18	85.5	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
647805818	438	16.9	14	345	7	358	1.0e-11	64.3	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
647805819	385	25.71	176	378	33	232	9.0e-15	74.7	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
647805820	246	41.92	52	245	41	224	3.0e-49	188	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
647805821	342	33.86	214	339	2	127	7.0e-15	74.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647805824	373	34.04	6	368	2	378	1.0e-67	250	COG0116	23S rRNA G2445 N2-methylase RlmL	381
647805825	577	19.79	52	519	21	433	2.0e-20	94.7	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
647805826	358	36.26	1	353	2	338	2.0e-87	316	COG3839	ABC-type sugar transport system, ATPase component	338
647805827	357	42.12	1	347	1	335	2.0e-97	349	COG3839	ABC-type sugar transport system, ATPase component	338
647805828	287	31.6	1	286	5	292	4.0e-46	178	COG1175	ABC-type sugar transport system, permease component	295
647805829	265	35.47	6	265	16	280	4.0e-45	174	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
647805830	92	54.35	1	92	6	97	2.0e-16	77.4	COG5477	Predicted small integral membrane protein	97
647805831	131	30.43	10	124	4	118	2.0e-14	71.4	COG3682	Predicted transcriptional regulator	123
647805832	380	18.58	3	346	2	335	1.0e-08	54.2	COG4219	Signal transducer regulating beta-lactamase production, contains  metallopeptidase domain	337
647805835	89	39.77	1	88	1	88	4.0e-18	83.3	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
647805836	134	34.33	1	130	1	134	1.0e-21	95.4	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
647805837	300	44.88	18	294	2	283	7.0e-80	290	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
647805839	577	30.26	233	577	7	329	1.0e-38	154	COG0642	Signal transduction histidine kinase	336
647805840	233	42.92	3	233	2	228	2.0e-56	212	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647805841	532	59.88	11	530	9	525	0.0e+00	739	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
647805842	227	18.57	25	221	10	209	4.0e-06	45.3	COG2755	Lysophospholipase L1 or related esterase	216
647805843	565	43.26	179	564	4	387	9.0e-79	288	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647805845	304	39.15	19	298	19	297	3.0e-62	232	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
647805846	182	41.86	7	175	3	167	3.0e-30	124	COG0431	NAD(P)H-dependent FMN reductase	184
647805847	221	41.57	42	219	13	190	7.0e-32	130	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
647805849	283	38.69	115	273	1	168	2.0e-34	139	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
647805850	214	55.12	10	214	6	210	1.0e-75	276	COG0177	Endonuclease III	211
647805851	330	27.85	7	316	2	295	4.0e-38	152	COG0524	Sugar or nucleoside kinase, ribokinase family	311
647805852	781	36.07	376	731	7	408	1.0e-53	204	COG0840	Methyl-accepting chemotaxis protein	408
647805853	162	30.71	32	158	3	126	6.0e-13	67.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
647805856	168	21.74	11	165	1	151	9.0e-08	50	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
647805857	675	43.25	2	355	1	362	2.0e-99	356	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
647805858	353	32.4	1	353	1	328	2.0e-46	180	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
647805859	301	34.23	3	295	2	293	6.0e-45	174	COG0583	DNA-binding transcriptional regulator, LysR family	297
647805861	115	31.43	1	102	1	105	3.0e-16	77.3	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
647805862	300	28.71	104	298	3	204	4.0e-22	98.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
647805864	190	29.31	12	182	3	176	2.0e-20	92.2	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
647805866	240	38.52	5	238	3	246	1.0e-54	206	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
647805867	242	53.48	11	240	1	226	4.0e-75	274	COG1489	DNA-binding protein, stimulates sugar fermentation	235
647805868	293	34.16	16	288	24	304	4.0e-39	155	COG0668	Small-conductance mechanosensitive channel	316
647805870	271	50.6	13	260	3	253	7.0e-83	300	COG0024	Methionine aminopeptidase	255
647805871	221	27.6	7	221	1	219	2.0e-33	136	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
647805872	188	43.16	1	183	2	186	4.0e-47	180	COG0742	16S rRNA G966 N2-methylase RsmD	187
647805873	403	31.07	4	403	1	408	6.0e-53	201	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
647805874	161	44.85	1	161	2	165	6.0e-46	176	COG0678	Peroxiredoxin	165
647805875	289	22.76	41	280	40	277	9.0e-07	47.7	COG5607	CHAD domain (function unknown)	283
647805877	97	48.45	1	97	2	96	5.0e-25	105	COG2154	Pterin-4a-carbinolamine dehydratase	101
647805878	395	54.76	4	390	6	387	0.0e+00	465	COG3146	Predicted N-acyltransferase	387
647805880	153	30.77	10	152	5	129	1.0e-17	82.3	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
647805882	587	47.26	12	575	13	577	0.0e+00	627	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
647805883	253	39.42	9	247	7	242	1.0e-49	190	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
647805884	196	21.46	1	196	1	202	3.0e-16	78.4	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
647805885	77	54.1	14	74	2	62	3.0e-18	83.3	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
647805887	167	52.67	17	166	3	151	5.0e-49	186	COG0691	tmRNA-binding protein	153
647805890	396	54.71	2	383	15	395	1.0e-88	320	COG3135	Predicted benzoate:H+ symporter BenE	402
647805891	614	54.07	1	612	8	574	0.0e+00	777	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
647805896	460	29.08	74	452	1	378	1.0e-46	181	COG0006	Xaa-Pro aminopeptidase	384
647805898	490	45.84	21	487	2	466	0.0e+00	506	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647805899	143	23.88	6	134	2	133	1.0e-09	56	COG1017	Hemoglobin-like flavoprotein	150
647805903	155	33.1	1	138	7	145	3.0e-24	104	COG0071	Molecular chaperone IbpA, HSP20 family	146
647805904	281	21.18	14	207	17	210	1.0e-11	64.2	COG3591	V8-like Glu-specific endopeptidase	251
647805905	439	28.12	20	420	6	387	1.0e-66	247	COG0247	Fe-S oxidoreductase	388
647805907	369	27	8	368	37	455	7.0e-29	121	COG0277	FAD/FMN-containing dehydrogenase	459
647805908	482	37.53	20	468	1	458	1.0e-83	304	COG0277	FAD/FMN-containing dehydrogenase	459
647805909	240	36.61	14	232	6	229	2.0e-40	159	COG3821	Uncharacterized membrane protein	234
647805911	156	43.4	1	155	1	155	2.0e-40	158	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
647805912	119	49.51	9	111	2	104	3.0e-31	126	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
647805915	467	58.09	2	467	1	422	0.0e+00	627	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
647805916	201	52.74	1	201	1	189	2.0e-74	272	COG0066	3-isopropylmalate dehydratase small subunit	191
647805918	357	51.61	4	340	9	335	7.0e-115	407	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
647805919	327	30.73	8	174	45	222	3.0e-24	106	COG2114	Adenylate cyclase, class 3	227
647805920	121	62.5	1	120	1	118	1.0e-38	151	COG0292	Ribosomal protein L20	118
647805921	66	50	1	64	1	64	3.0e-09	53.3	COG0291	Ribosomal protein L35	65
647805923	481	48	1	468	1	475	0.0e+00	547	COG0469	Pyruvate kinase	477
647805924	288	44.36	36	287	24	280	4.0e-48	185	COG5473	Uncharacterized membrane protein	290
647805925	334	45.15	9	330	1	326	2.0e-74	273	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647805926	232	30.22	16	196	29	210	2.0e-27	116	COG5590	Ubiquinone biosynthesis protein COQ9	229
647805928	630	45.94	26	627	5	581	0.0e+00	619	COG0322	Excinuclease UvrABC, nuclease subunit	581
647805929	258	35.02	1	245	6	250	4.0e-28	118	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647805930	314	40.84	1	310	9	314	2.0e-43	169	COG0530	Ca2+/Na+ antiporter	320
647805931	298	37.15	47	293	61	311	8.0e-55	207	COG0616	Periplasmic serine protease, ClpP class	317
647805933	253	24.66	24	246	42	253	3.0e-09	55.9	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
647805934	309	36.25	1	306	1	293	5.0e-67	247	COG1131	ABC-type multidrug transport system, ATPase component	293
647805935	195	44.59	15	161	1	146	2.0e-30	125	COG3427	Carbon monoxide dehydrogenase subunit G	146
647805936	347	43.6	1	342	4	346	1.0e-98	353	COG0407	Uroporphyrinogen-III decarboxylase	352
647805937	318	48.21	11	316	3	302	4.0e-91	328	COG0181	Porphobilinogen deaminase	307
647805938	316	23.08	11	316	27	321	3.0e-25	109	COG3239	Fatty acid desaturase	343
647805939	290	43.53	52	280	40	269	6.0e-61	227	COG3757	Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family	269
647805940	300	42.81	6	299	1	278	2.0e-88	319	COG0408	Coproporphyrinogen III oxidase	303
647805941	267	32.06	3	257	1	251	4.0e-38	151	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647805943	328	36.53	62	323	29	299	9.0e-55	207	COG2813	16S rRNA G1207 methylase RsmC	300
647805944	107	53.77	1	106	2	107	1.0e-31	127	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
647805945	237	25.94	3	236	2	229	4.0e-18	85.3	COG1011	FMN phosphatase YigB, HAD superfamily	229
647805946	559	34.89	31	391	5	360	3.0e-76	279	COG1686	D-alanyl-D-alanine carboxypeptidase	389
647805947	52	46.15	1	52	1	52	6.0e-10	56	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
647805948	727	42.4	31	727	3	708	0.0e+00	591	COG2217	Cation transport ATPase	713
647805949	158	35.19	1	157	1	162	2.0e-26	112	COG5456	Nitrogen fixation protein FixH	166
647805950	476	33.65	19	436	1	383	2.0e-75	276	COG0348	Polyferredoxin	386
647805951	294	25.42	7	292	1	295	2.0e-28	120	COG0583	DNA-binding transcriptional regulator, LysR family	297
647805953	294	29.81	65	222	3	150	2.0e-15	76.2	COG2010	Cytochrome c, mono- and diheme variants	150
647805954	65	32.14	2	57	1	56	1.0e-07	48.3	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
647805955	242	63.2	6	236	2	224	5.0e-99	353	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
647805956	534	69.17	54	533	2	480	0.0e+00	680	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
647805958	261	32.37	41	244	12	214	1.0e-31	130	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
647805959	445	31	12	438	7	416	2.0e-98	353	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
647805960	530	63.71	1	526	1	529	0.0e+00	772	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
647805961	368	55.98	1	367	2	341	2.0e-122	432	COG4239	ABC-type microcin C transport system, permease component YejE	341
647805962	362	67.03	1	361	1	364	0.0e+00	547	COG4174	ABC-type microcin C transport system, permease component YejB	364
647805963	646	25.08	29	637	9	562	1.0e-66	248	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
647805964	166	46.46	43	165	7	131	2.0e-29	122	COG3474	Cytochrome c2	135
647805965	276	41.58	1	276	1	278	2.0e-77	282	COG0077	Prephenate dehydratase	279
647805966	627	47.24	20	627	5	615	0.0e+00	557	COG3211	Secreted phosphatase, PhoX family	616
647805967	241	28.19	1	217	4	229	5.0e-32	131	COG1381	Recombinational DNA repair protein (RecF pathway)	251
647805968	109	32.41	3	104	2	109	7.0e-11	58.9	COG5447	Uncharacterized protein	115
647805969	301	45.15	1	298	2	298	3.0e-101	361	COG1159	GTPase Era, involved in 16S rRNA processing	298
647805970	228	40.69	1	227	2	232	3.0e-58	218	COG0571	dsRNA-specific ribonuclease	235
647805971	278	26.71	18	140	16	163	1.0e-12	66.9	COG0681	Signal peptidase I	166
647805972	139	41.98	1	131	1	127	2.0e-35	141	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
647805974	252	57.61	6	248	1	243	7.0e-81	293	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
647805976	234	28.5	1	200	1	180	2.0e-24	105	COG3216	Uncharacterized conserved protein, DUF2062 family	184
647805979	117	54.05	1	72	1	74	1.0e-11	61.9	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
647805980	195	38.33	16	194	6	160	1.0e-30	126	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
647805981	189	42.22	6	182	6	178	3.0e-36	144	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
647805983	556	66.38	6	234	1	229	4.0e-99	355	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
647805987	161	60.13	7	156	7	154	1.0e-46	179	COG0328	Ribonuclease HI	154
647805988	207	41.83	1	207	3	209	3.0e-42	164	COG2860	Uncharacterized membrane protein YeiH	209
647805991	308	49.35	1	299	2	307	2.0e-103	369	COG0223	Methionyl-tRNA formyltransferase	307
647805992	165	41.67	1	165	1	168	4.0e-39	154	COG0242	Peptide deformylase	168
647805993	169	46.11	1	165	1	167	2.0e-46	178	COG0242	Peptide deformylase	168
647805994	174	53.29	1	167	2	168	2.0e-57	215	COG0242	Peptide deformylase	168
647805995	390	41.22	1	390	2	388	4.0e-117	415	COG1168	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	388
647805997	324	67.8	1	323	1	320	0.0e+00	523	COG0435	Glutathionyl-hydroquinone reductase	324
647805998	332	25.43	20	331	2	348	6.0e-41	161	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
647805999	303	45.14	1	302	3	315	1.0e-65	243	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
647806000	398	40.5	14	330	21	339	1.0e-79	290	COG2951	Membrane-bound lytic murein transglycosylase B	343
647806001	1151	31.62	1	1150	1	1163	0.0e+00	535	COG1196	Chromosome segregation ATPase	1163
647806002	404	44.62	27	404	87	457	1.0e-99	356	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
647806004	273	40.28	1	208	1	207	2.0e-38	152	COG2186	DNA-binding transcriptional regulator, FadR family	241
647806005	185	32.68	31	183	10	161	1.0e-10	59.5	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
647806006	181	29.5	27	165	2	140	1.0e-10	59.9	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
647806008	267	35.19	52	264	31	244	7.0e-33	134	COG0356	FoF1-type ATP synthase, membrane subunit a	246
647806009	113	36.04	3	112	6	114	8.0e-15	72.3	COG5336	FoF1-type ATP synthase assembly protein I	116
647806011	109	33.75	1	79	11	90	6.0e-08	49.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
647806013	292	25.08	3	292	2	296	1.0e-27	117	COG0583	DNA-binding transcriptional regulator, LysR family	297
647806014	193	42.5	4	192	3	202	4.0e-49	187	COG1182	FMN-dependent NADH-azoreductase	202
647806015	175	38.51	12	172	2	157	6.0e-32	130	COG3760	Uncharacterized protein	164
647806017	519	52.55	6	456	1	448	0.0e+00	536	COG0541	Signal recognition particle GTPase	451
647806018	176	23.81	5	162	3	170	3.0e-13	68.1	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
647806019	201	23.46	6	174	2	180	6.0e-11	61.1	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
647806020	102	30.85	8	100	2	95	2.0e-12	63.8	COG1605	Chorismate mutase	101
647806021	119	68.54	2	90	1	87	2.0e-26	110	COG0228	Ribosomal protein S16	87
647806022	217	26.09	17	192	2	185	9.0e-18	83.9	COG0778	Nitroreductase	207
647806024	171	39.52	6	169	5	171	1.0e-39	155	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
647806026	294	53.16	105	293	45	232	9.0e-76	277	COG0336	tRNA G37 N-methylase TrmD	240
647806028	110	69.49	1	59	1	59	4.0e-15	73.4	COG3422	Uncharacterized conserved protein YegP, UPF0339 family	59
647806029	141	33.33	4	105	1	108	2.0e-11	62.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
647806030	400	19.65	1	397	1	393	4.0e-07	49.8	COG2814	Predicted arabinose efflux permease, MFS family	394
647806031	123	63.79	1	116	3	114	2.0e-37	148	COG0335	Ribosomal protein L19	115
647806032	73	40	1	73	1	72	2.0e-15	74.1	COG0254	Ribosomal protein L31	75
647806033	269	21.19	1	250	1	249	2.0e-19	89.9	COG1192	Cellulose biosynthesis protein BcsQ	259
647806035	415	30.22	186	410	7	213	2.0e-25	110	COG2114	Adenylate cyclase, class 3	227
647806036	152	25.4	19	143	1	126	2.0e-10	58.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
647806037	451	58.87	23	443	5	424	0.0e+00	544	COG3508	Homogentisate 1,2-dioxygenase	427
647806038	418	19.69	39	361	1	250	6.0e-23	102	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
647806039	316	14.78	15	237	6	228	2.0e-10	60.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647806040	535	22.92	25	404	2	377	2.0e-49	190	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647806042	211	35.47	6	203	3	201	3.0e-25	108	COG0625	Glutathione S-transferase	211
647806043	395	26.11	30	336	7	260	3.0e-20	93.4	COG0391	Archaeal 2-phospho-L-lactate transferase/Bacterial gluconeogenesis factor, CofD/UPF0052 family	323
647806044	740	41.57	94	718	26	627	0.0e+00	488	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
647806045	112	62.5	1	112	1	112	3.0e-36	143	COG0347	Nitrogen regulatory protein PII	112
647806046	440	37.35	38	437	5	405	2.0e-80	293	COG0004	Ammonia channel protein AmtB	409
647806047	214	35.81	5	198	16	229	2.0e-39	155	COG3719	Ribonuclease I	249
647806048	255	47.01	4	252	5	230	4.0e-61	228	COG3820	Uncharacterized protein	230
647806050	283	45.58	1	283	6	285	5.0e-84	304	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
647806051	394	49.11	1	392	1	395	0.0e+00	474	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
647806052	258	36.15	3	257	2	260	2.0e-71	262	COG3622	Hydroxypyruvate isomerase	260
647806053	333	34.32	1	326	4	340	4.0e-50	191	COG0673	Predicted dehydrogenase	342
647806054	371	35.22	1	371	2	340	1.0e-55	210	COG0673	Predicted dehydrogenase	342
647806055	276	26.14	18	276	6	264	2.0e-34	139	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
647806056	308	26.28	4	306	14	322	1.0e-33	137	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
647806057	368	34.59	21	363	4	312	2.0e-48	186	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
647806059	637	54.19	332	636	1	310	3.0e-115	409	COG3892	Myo-inositol catabolism protein IolC	310
647806060	609	63.13	1	606	2	614	0.0e+00	902	COG3962	TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism	617
647806061	301	29.97	5	291	1	271	8.0e-31	128	COG1082	Sugar phosphate isomerase/epimerase	274
647806062	268	59.7	1	267	1	268	4.0e-109	387	COG3718	5-deoxy-D-glucuronate isomerase	270
647806063	366	35.31	12	357	1	348	2.0e-68	252	COG3191	L-aminopeptidase/D-esterase	348
647806064	283	42.09	5	282	4	263	2.0e-57	215	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
647806065	296	50.18	15	294	12	283	1.0e-61	230	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
647806066	361	48.48	1	360	2	352	1.0e-109	389	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
647806067	343	35.69	4	343	11	363	3.0e-57	215	COG0687	Spermidine/putrescine-binding periplasmic protein	363
647806068	319	25	79	316	42	281	1.0e-25	110	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
647806069	209	40.89	10	202	14	215	8.0e-28	117	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647806070	249	36.56	5	228	6	231	1.0e-42	166	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647806072	448	36.11	6	448	2	454	2.0e-82	299	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
647806073	266	34.34	3	258	2	260	2.0e-42	166	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
647806074	398	26.75	17	388	46	419	3.0e-32	133	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
647806075	333	42.34	3	327	6	327	6.0e-73	267	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
647806076	230	24.8	3	228	7	243	8.0e-18	84.1	COG1651	Protein-disulfide isomerase	244
647806077	175	33.1	36	168	50	180	3.0e-15	75	COG5389	Uncharacterized protein	181
647806078	353	42.37	1	351	1	340	2.0e-96	345	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
647806080	488	26.01	96	466	17	408	8.0e-36	145	COG0840	Methyl-accepting chemotaxis protein	408
647806081	464	29.22	244	462	20	214	1.0e-27	118	COG2114	Adenylate cyclase, class 3	227
647806082	385	34.27	32	310	16	298	4.0e-57	215	COG0863	DNA modification methylase	302
647806083	208	56.15	23	205	2	188	1.0e-60	226	COG0164	Ribonuclease HII	199
647806088	517	29.49	301	513	13	213	1.0e-28	121	COG2114	Adenylate cyclase, class 3	227
647806089	505	35.44	23	493	12	471	1.0e-103	370	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647806090	373	26.46	4	362	3	379	6.0e-66	244	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
647806091	142	35.42	1	141	6	149	3.0e-21	94.4	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647806092	251	43.48	1	250	1	250	6.0e-61	227	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
647806093	679	45.62	1	590	2	584	0.0e+00	633	COG0514	Superfamily II DNA helicase RecQ	590
647806096	461	31.74	1	459	1	433	2.0e-70	259	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
647806097	307	47.27	54	306	36	276	1.0e-72	266	COG3770	Murein endopeptidase	284
647806098	309	33.96	56	305	73	337	3.0e-27	115	COG4246	Uncharacterized protein	340
647806099	210	33.8	9	200	30	220	1.0e-21	96.9	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
647806101	340	40.92	1	331	9	331	9.0e-62	230	COG3191	L-aminopeptidase/D-esterase	348
647806104	206	23.27	1	187	2	201	6.0e-15	74.6	COG1011	FMN phosphatase YigB, HAD superfamily	229
647806105	305	32.7	1	299	2	316	6.0e-48	184	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
647806107	412	20.84	35	411	38	394	1.0e-13	71.4	COG2814	Predicted arabinose efflux permease, MFS family	394
647806109	357	44.63	1	356	6	365	5.0e-109	387	COG1485	Predicted ATPase	367
647806110	250	35.77	7	248	4	249	5.0e-49	187	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
647806111	423	44.34	1	423	2	422	3.0e-105	375	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
647806112	320	54.2	1	284	1	286	1.0e-108	386	COG0777	Acetyl-CoA carboxylase beta subunit	294
647806114	1029	23.45	15	481	1	444	5.0e-40	160	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647806119	354	45.99	2	188	1	187	7.0e-57	214	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
647806128	627	52.35	302	619	1	316	3.0e-117	416	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
647806129	315	48.73	1	314	1	314	1.0e-88	320	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647806130	528	34.94	1	528	1	553	6.0e-94	338	COG0747	ABC-type transport system, periplasmic component	556
647806131	224	38	1	193	1	199	3.0e-31	128	COG3342	Uncharacterized conserved protein, Ntn-hydrolase superfamily	265
647806132	262	30.49	15	256	4	241	3.0e-28	118	COG2186	DNA-binding transcriptional regulator, FadR family	241
647806133	406	22.49	23	406	22	409	1.0e-30	127	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647806134	741	24.82	61	462	57	482	3.0e-08	54.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
647806135	457	40.04	4	457	2	446	0.0e+00	495	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
647806136	491	45.55	23	491	4	470	0.0e+00	480	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647806137	159	35.53	1	152	4	154	2.0e-30	124	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647806138	330	44.34	1	327	1	326	9.0e-87	313	COG3608	Predicted deacylase	331
647806139	339	31.1	16	334	4	326	3.0e-45	176	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
647806141	335	22.92	5	330	11	312	3.0e-28	119	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
647806142	346	40.73	24	346	5	333	1.0e-48	187	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
647806143	253	43.87	1	248	1	253	2.0e-75	275	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
647806144	140	38.68	9	112	23	128	1.0e-20	92.4	COG3794	Plastocyanin	128
647806147	279	40.24	31	275	1	246	1.0e-54	206	COG1414	DNA-binding transcriptional regulator, IclR family	246
647806148	396	38.34	1	385	2	382	6.0e-104	371	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
647806149	321	39.69	4	318	2	321	6.0e-84	304	COG1171	Threonine dehydratase	347
647806150	387	32.53	21	382	10	368	5.0e-59	222	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
647806151	321	36.7	1	321	4	329	3.0e-60	225	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
647806152	302	28.57	4	299	3	296	2.0e-37	149	COG0583	DNA-binding transcriptional regulator, LysR family	297
647806153	487	62.45	2	481	4	483	0.0e+00	669	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
647806154	777	73.02	7	777	12	778	0.0e+00	1241	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
647806155	283	31.46	5	262	6	257	1.0e-30	127	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
647806156	527	21.24	11	383	1	388	9.0e-13	68.7	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
647806157	161	34.67	1	150	6	154	7.0e-25	106	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647806158	348	29.77	39	344	24	313	1.0e-44	173	COG1171	Threonine dehydratase	347
647806159	387	29.67	5	387	2	384	3.0e-53	202	COG0006	Xaa-Pro aminopeptidase	384
647806160	251	34.67	11	233	3	224	7.0e-35	140	COG3473	Maleate cis-trans isomerase	238
647806161	367	36.31	8	363	11	379	2.0e-67	249	COG0006	Xaa-Pro aminopeptidase	384
647806162	529	26.12	1	523	4	548	6.0e-55	209	COG0747	ABC-type transport system, periplasmic component	556
647806164	347	44.48	22	347	9	314	3.0e-80	292	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647806165	301	53.82	28	300	15	289	2.0e-75	275	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647806166	279	55.22	6	269	1	268	2.0e-97	349	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
647806167	249	50.81	1	241	1	245	5.0e-82	297	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
647806170	165	45.83	19	162	11	154	6.0e-32	130	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
647806171	273	22.69	149	263	7	124	1.0e-09	57.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
647806173	185	34.55	1	159	12	176	1.0e-28	119	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
647806174	569	31.09	343	531	8	194	3.0e-28	120	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
647806177	195	28.9	20	192	21	188	5.0e-18	84.5	COG3932	Uncharacterized conserved protein	209
647806181	342	29.36	13	333	15	340	1.0e-29	124	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
647806183	395	44.44	4	395	6	396	2.0e-102	365	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
647806184	506	47.5	1	500	3	497	9.0e-125	440	COG3333	TctA family transporter	504
647806186	326	31.15	7	326	3	318	6.0e-57	214	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
647806187	221	42.04	1	218	1	225	5.0e-49	187	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647806188	461	28.34	157	461	30	330	7.0e-34	138	COG0642	Signal transduction histidine kinase	336
647806189	340	23.47	62	338	9	296	1.0e-17	84.4	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
647806190	794	27.2	8	793	74	868	0.0e+00	680	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
647806191	400	48.85	1	392	2	393	0.0e+00	468	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
647806192	152	44.97	1	149	6	153	1.0e-34	138	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647806193	627	35.92	1	617	1	624	3.0e-123	436	COG3525	N-acetyl-beta-hexosaminidase	732
647806196	270	49.81	4	262	1	263	2.0e-91	329	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
647806197	302	39.29	1	277	11	287	1.0e-55	210	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647806198	325	36.31	1	325	2	316	6.0e-71	261	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647806199	551	25.5	3	526	16	542	3.0e-57	216	COG0747	ABC-type transport system, periplasmic component	556
647806201	1136	33.33	296	657	5	328	1.0e-42	169	COG0642	Signal transduction histidine kinase	336
647806202	173	28.4	9	170	8	169	8.0e-17	80	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647806203	428	46.84	46	425	1	379	3.0e-85	309	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647806204	347	33.74	1	324	2	321	3.0e-59	222	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647806205	488	53.56	1	488	1	488	0.0e+00	537	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
647806206	351	39.94	1	346	12	368	2.0e-84	306	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
647806207	308	34.38	6	306	2	311	3.0e-45	175	COG0524	Sugar or nucleoside kinase, ribokinase family	311
647806208	129	46.43	19	127	18	129	2.0e-28	118	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
647806209	445	46.58	2	372	1	374	2.0e-97	349	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
647806210	381	22.76	9	376	22	419	2.0e-26	113	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
647806211	506	56.08	2	505	1	507	0.0e+00	629	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
647806214	207	33.65	1	207	1	207	1.0e-21	96.5	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
647806215	168	22.76	1	133	2	140	3.0e-06	44.9	COG1247	L-amino acid N-acyltransferase YncA	169
647806216	309	40.39	4	307	3	292	8.0e-71	260	COG1131	ABC-type multidrug transport system, ATPase component	293
647806217	60	39.13	5	50	14	58	3.0e-08	50.4	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
647806220	935	52.04	328	935	3	593	0.0e+00	740	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
647806222	255	42.15	1	255	1	260	2.0e-65	242	COG3622	Hydroxypyruvate isomerase	260
647806223	197	52.85	12	195	9	201	3.0e-60	224	COG3816	Uncharacterized protein	205
647806224	335	43.48	12	324	9	321	5.0e-61	228	COG0714	MoxR-like ATPase	329
647806228	284	26.81	44	273	30	257	4.0e-23	101	COG3971	2-keto-4-pentenoate hydratase	264
647806229	726	44.88	52	724	4	733	0.0e+00	584	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
647806231	1764	35.55	325	1711	123	1515	0.0e+00	835	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
647806232	753	34.53	121	452	17	333	8.0e-44	172	COG0642	Signal transduction histidine kinase	336
647806233	452	48.57	2	441	1	453	2.0e-120	426	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
647806234	422	39.67	2	421	1	404	8.0e-101	360	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
647806235	337	59.59	3	336	1	323	0.0e+00	490	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
647806236	413	45.08	55	413	1	358	3.0e-108	385	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
647806237	356	29.2	5	352	29	408	8.0e-64	237	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
647806238	170	41.89	23	170	7	153	9.0e-28	116	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647806239	381	43.01	7	381	4	377	2.0e-116	412	COG1454	Alcohol dehydrogenase, class IV	377
647806240	460	34.72	4	457	15	469	1.0e-100	360	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647806241	450	38.48	1	448	1	442	6.0e-112	398	COG0174	Glutamine synthetase	443
647806242	344	23.21	4	334	3	346	2.0e-26	113	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
647806244	439	32.89	1	438	2	447	1.0e-63	237	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
647806245	195	24.32	5	187	4	167	4.0e-16	78.4	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
647806246	254	42.91	7	251	7	252	1.0e-65	243	COG3931	Predicted N-formylglutamate amidohydrolase	263
647806247	285	29.08	3	280	4	281	2.0e-45	176	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
647806249	373	31.51	9	368	6	387	2.0e-39	157	COG0183	Acetyl-CoA acetyltransferase	392
647806250	738	69.9	8	738	14	730	0.0e+00	1113	COG0376	Catalase (peroxidase I)	730
647806251	307	35.12	4	300	1	297	2.0e-38	152	COG0583	DNA-binding transcriptional regulator, LysR family	297
647806252	262	41.67	1	259	1	257	2.0e-48	185	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647806253	679	29.52	1	604	1	598	7.0e-86	312	COG1042	Acyl-CoA synthetase (NDP forming)	598
647806254	104	70.21	7	100	2	94	2.0e-36	143	COG3526	Predicted selenoprotein, Rdx family	99
647806255	387	44.44	1	387	1	392	4.0e-86	311	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647806256	315	37.9	9	313	8	321	8.0e-60	224	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
647806258	139	26.09	1	115	1	115	3.0e-23	100	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
647806259	601	47.74	3	596	1	583	0.0e+00	629	COG1001	Adenine deaminase	584
647806260	488	23.74	211	466	1	233	6.0e-41	162	COG0775	Nucleoside phosphorylase	234
647806261	97	45.65	4	95	1	92	1.0e-16	77.9	COG0776	Bacterial nucleoid DNA-binding protein	94
647806263	149	61.76	2	137	1	136	3.0e-56	210	COG0229	Peptide methionine sulfoxide reductase MsrB	140
647806264	171	47.34	4	166	6	174	1.0e-58	219	COG0225	Peptide methionine sulfoxide reductase MsrA	174
647806265	668	29.92	1	628	1	635	9.0e-80	291	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
647806266	347	45.75	7	345	2	337	1.0e-88	320	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
647806267	221	32.84	4	201	3	200	8.0e-31	127	COG0625	Glutathione S-transferase	211
647806269	1510	54.4	717	1201	2	484	0.0e+00	601	COG0069	Glutamate synthase domain 2	485
647806270	480	43.07	24	477	1	456	2.0e-124	440	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
647806271	267	36.19	1	266	4	268	2.0e-45	176	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
647806272	329	32.56	3	259	1	247	5.0e-25	108	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
647806275	118	45.28	9	114	8	113	3.0e-29	120	COG1733	DNA-binding transcriptional regulator, HxlR family	120
647806276	154	43.41	30	154	1	129	1.0e-32	132	COG4922	Predicted SnoaL-like aldol condensation-catalyzing enzyme	129
647806277	600	36.97	281	585	81	408	4.0e-39	156	COG0840	Methyl-accepting chemotaxis protein	408
647806278	367	56.11	2	358	1	355	0.0e+00	501	COG0082	Chorismate synthase	369
647806279	325	53.89	1	325	4	336	2.0e-99	356	COG4143	ABC-type thiamine transport system, periplasmic component	336
647806280	523	30.91	3	520	1	535	4.0e-58	219	COG1178	ABC-type Fe3+ transport system, permease component	540
647806281	225	52.38	16	224	22	231	4.0e-64	237	COG3840	ABC-type thiamine transport system, ATPase component	231
647806282	200	25.12	1	200	1	206	1.0e-17	83.3	COG0625	Glutathione S-transferase	211
647806283	186	35.29	1	186	1	166	1.0e-37	149	COG0723	Rieske Fe-S protein	177
647806284	442	45.91	9	408	1	372	3.0e-87	316	COG1290	Cytochrome b subunit of the bc complex	381
647806285	263	31.94	3	256	2	248	4.0e-36	145	COG2857	Cytochrome c1	250
647806286	173	25.45	4	149	25	189	8.0e-20	90.1	COG3896	Chloramphenicol 3-O-phosphotransferase	205
647806287	419	37.93	8	419	10	433	1.0e-117	416	COG0621	tRNA A37 methylthiotransferase MiaB	437
647806288	275	41.7	2	265	1	270	2.0e-74	272	COG0253	Diaminopimelate epimerase	272
647806300	487	20.53	75	475	44	455	9.0e-26	111	COG1538	Outer membrane protein TolC	457
647806301	452	24.59	57	413	13	358	3.0e-33	136	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
647806302	238	41.25	1	159	1	156	6.0e-28	117	COG4454	Uncharacterized copper-binding protein, cupredoxin-like subfamily	158
647806305	716	38.66	356	674	65	408	3.0e-40	160	COG0840	Methyl-accepting chemotaxis protein	408
647806325	685	38.68	4	554	6	550	1.0e-122	434	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
647806326	391	23.27	115	370	20	284	2.0e-10	60.6	COG4974	Site-specific recombinase XerD	300
647806330	321	23.62	89	317	45	291	7.0e-09	55.2	COG4974	Site-specific recombinase XerD	300
647806335	238	27.68	41	210	17	186	2.0e-12	66.3	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
647806342	434	26.1	1	361	1	372	6.0e-35	142	COG3950	Predicted ATP-binding protein involved in virulence	440
647806346	611	23.99	18	586	2	528	2.0e-60	227	COG4626	Phage terminase-like protein, large subunit, contains N-terminal HTH domain	546
647806347	441	25.44	4	393	2	392	7.0e-38	152	COG4695	Phage portal protein BeeE	398
647806348	197	32.75	6	171	3	170	2.0e-22	99.3	COG3740	Phage head maturation protease	194
647806349	447	23.13	75	447	31	421	7.0e-27	115	COG4653	Predicted phage phi-C31 gp36 major capsid-like protein	422
647806366	240	40.79	92	239	1	152	3.0e-36	145	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
647806369	267	27.89	2	241	1	244	1.0e-19	90.4	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
647806370	316	29.24	13	310	1	297	5.0e-40	158	COG1597	Diacylglycerol kinase family enzyme	301
647806371	476	35.78	14	474	8	467	9.0e-111	394	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647806372	501	27.86	8	493	2	467	7.0e-59	221	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647806373	335	40.73	1	328	2	328	7.0e-88	317	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
647806374	239	29.82	9	235	2	228	2.0e-24	106	COG1802	DNA-binding transcriptional regulator, GntR family	230
647806375	303	28.67	1	289	2	288	6.0e-39	154	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
647806376	391	34.44	39	391	22	370	4.0e-68	252	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
647806377	327	40.48	1	327	2	332	3.0e-77	282	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647806378	187	25.14	1	174	4	177	1.0e-12	66.5	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647806379	426	50	48	425	1	378	5.0e-91	328	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647806380	497	31.19	5	438	1	426	8.0e-57	214	COG3898	Uncharacterized membrane-anchored protein	531
647806382	245	24.08	5	229	1	242	2.0e-17	83.2	COG1587	Uroporphyrinogen-III synthase	248
647806383	365	48.41	5	350	1	336	9.0e-112	396	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
647806384	320	45.73	1	320	2	329	2.0e-89	322	COG0240	Glycerol-3-phosphate dehydrogenase	329
647806385	90	39.13	1	89	1	92	8.0e-15	71.9	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
647806386	140	50	1	140	2	155	2.0e-47	181	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
647806389	461	53.39	1	453	1	420	0.0e+00	615	COG0499	S-adenosylhomocysteine hydrolase	420
647806391	208	27.27	26	207	1	186	7.0e-23	100	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
647806393	184	72.32	9	184	6	182	3.0e-65	241	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
647806394	207	36.82	3	200	1	200	5.0e-31	127	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
647806395	465	21.81	106	448	10	334	8.0e-18	85.6	COG0642	Signal transduction histidine kinase	336
647806397	158	45.14	7	149	2	142	7.0e-33	133	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
647806398	332	36.65	11	327	2	350	7.0e-54	204	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
647806400	977	31.62	9	697	1	697	1.0e-76	281	COG3893	Inactivated superfamily I helicase	697
647806401	1121	25.94	7	1103	6	1139	0.0e+00	514	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
647806404	185	63.07	9	183	2	175	1.0e-65	242	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
647806406	436	61.07	1	436	1	444	0.0e+00	636	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
647806407	373	33.33	13	324	2	320	3.0e-50	192	COG4782	Esterase/lipase superfamily enzyme	377
647806408	200	31.16	1	198	2	180	8.0e-21	93.8	COG2840	DNA-nicking endonuclease, Smr domain	184
647806409	352	34.24	5	340	4	365	3.0e-69	255	COG2821	Membrane-bound lytic murein transglycosylase	373
647806410	218	23.53	1	218	44	279	2.0e-26	112	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
647806411	165	36.81	3	165	5	155	1.0e-24	105	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
647806412	163	37.97	6	163	2	156	1.0e-35	142	COG1952	Preprotein translocase subunit SecB	157
647806413	243	34.3	1	240	13	238	2.0e-41	162	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
647806414	198	34.17	2	197	1	199	1.0e-37	149	COG0237	Dephospho-CoA kinase	201
647806415	276	42.24	1	274	1	277	2.0e-78	286	COG0169	Shikimate 5-dehydrogenase	283
647806416	199	30.81	1	197	1	190	1.0e-39	156	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
647806417	151	41.22	4	150	1	147	4.0e-28	117	COG1981	Uncharacterized membrane protein	149
647806419	423	70.71	4	423	2	420	0.0e+00	681	COG1158	Transcription termination factor Rho	422
647806420	428	39.29	1	428	4	454	1.0e-110	393	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
647806421	624	56.01	3	615	2	616	0.0e+00	856	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
647806422	205	38.95	11	193	15	200	2.0e-39	155	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
647806423	267	42.13	7	258	2	251	1.0e-56	213	COG1192	Cellulose biosynthesis protein BcsQ	259
647806424	299	39.06	42	293	7	240	1.0e-33	136	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
647806426	384	41.07	1	384	27	412	2.0e-102	366	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
647806427	204	45.31	9	199	3	188	2.0e-54	205	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
647806428	237	53.39	1	235	8	228	3.0e-70	258	COG0689	Ribonuclease PH	230
647806429	354	40.29	11	354	4	344	6.0e-86	311	COG1420	Transcriptional regulator of heat shock response	346
647806430	187	40.7	14	185	24	193	5.0e-30	124	COG0576	Molecular chaperone GrpE (heat shock protein)	193
647806431	879	47.39	2	875	5	843	0.0e+00	877	COG0249	DNA mismatch repair ATPase MutS	843
647806432	282	21.09	2	273	1	273	2.0e-14	72.8	COG1344	Flagellin and related hook-associated protein FlgL	360
647806433	751	57.14	5	428	15	427	0.0e+00	585	COG0281	Malic enzyme	432
647806434	290	36.63	3	286	2	304	1.0e-39	156	COG0524	Sugar or nucleoside kinase, ribokinase family	311
647806435	221	49.34	27	176	1	152	1.0e-52	200	COG0225	Peptide methionine sulfoxide reductase MsrA	174
647806436	93	33.33	1	93	21	119	2.0e-11	61.2	COG3255	Putative sterol carrier protein	134
647806437	128	37.93	15	128	29	144	2.0e-24	104	COG5480	Uncharacterized membrane protein	147
647806438	153	41.48	19	153	7	141	4.0e-27	113	COG5579	Uncharacterized protein, DUF1810 family	143
647806439	407	56.97	1	407	1	403	0.0e+00	585	COG0137	Argininosuccinate synthase	403
647806441	408	46.15	10	338	14	347	5.0e-100	357	COG1171	Threonine dehydratase	347
647806444	147	24.35	18	127	10	119	1.0e-05	42.7	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
647806445	325	30.25	10	318	4	283	1.0e-60	227	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
647806446	199	17.76	34	176	7	153	1.0e-05	43.4	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
647806447	386	29.66	6	382	4	404	1.0e-54	207	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
647806448	612	34.25	24	604	6	567	3.0e-120	426	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647806449	614	33.86	35	601	15	567	5.0e-108	385	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647806450	414	31.02	8	406	6	431	6.0e-67	248	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
647806453	164	22.29	9	162	48	204	3.0e-15	74.5	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
647806457	353	42.64	25	350	5	320	2.0e-99	356	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
647806459	243	39.74	12	240	7	223	3.0e-34	138	COG1040	Predicted amidophosphoribosyltransferases	225
647806460	85	57.5	2	80	1	80	2.0e-22	97	COG0695	Glutaredoxin	80
647806461	277	37.14	1	275	2	266	5.0e-50	191	COG0388	Predicted amidohydrolase	274
647806462	146	24.3	31	137	17	122	2.0e-08	51.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
647806463	247	51.82	1	247	5	242	7.0e-82	296	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
647806464	326	22.38	25	306	3	265	9.0e-17	81.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647806466	244	40.52	52	203	6	153	5.0e-37	148	COG0779	Ribosome maturation factor RimP	153
647806467	538	54.12	166	358	3	190	6.0e-50	192	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
647806468	205	41.67	14	97	7	88	2.0e-17	82.7	COG2740	Predicted RNA-binding protein YlxR, DUF448 family	95
647806469	837	58.07	332	837	1	508	0.0e+00	625	COG0532	Translation initiation factor IF-2, a GTPase	509
647806470	136	35.85	1	106	2	106	1.0e-09	55.8	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
647806471	408	49.63	8	408	2	404	2.0e-122	432	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
647806472	283	21.89	29	275	48	311	4.0e-17	82.5	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
647806473	897	54.35	4	887	1	820	0.0e+00	1026	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
647806475	517	23.12	58	359	22	311	1.0e-15	78.2	COG0226	ABC-type phosphate transport system, periplasmic component	318
647806476	447	18.09	19	275	2	292	7.0e-15	75.8	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647806477	155	58.71	1	155	1	155	9.0e-39	152	COG5528	Uncharacterized membrane protein	155
647806478	642	56.83	7	633	2	623	0.0e+00	851	COG1154	Deoxyxylulose-5-phosphate synthase	627
647806479	287	39.33	5	287	3	322	1.0e-51	196	COG0142	Geranylgeranyl pyrophosphate synthase	322
647806480	81	36.11	1	72	1	72	2.0e-10	57.6	COG1722	Exonuclease VII small subunit	81
647806481	308	43.41	1	303	2	309	5.0e-78	284	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
647806482	233	37.83	6	233	1	228	2.0e-52	198	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647806483	170	21.93	43	156	13	126	2.0e-09	55.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
647806484	288	36.97	8	288	1	282	4.0e-66	244	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
647806486	142	41.73	6	142	7	143	5.0e-31	126	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
647806487	143	42.74	20	142	4	126	1.0e-11	62.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
647806489	220	27.19	1	203	1	217	5.0e-28	118	COG1230	Co/Zn/Cd efflux system component	296
647806490	138	39.81	2	108	1	108	4.0e-20	90.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
647806491	315	21.22	32	305	8	312	8.0e-15	75	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647806492	93	37.23	1	93	1	93	1.0e-14	71.2	COG3553	Uncharacterized protein	96
647806493	298	44.63	3	296	23	320	1.0e-75	276	COG4607	ABC-type enterochelin transport system, periplasmic component	320
647806494	316	45.25	1	314	4	319	1.0e-80	293	COG4606	ABC-type enterochelin transport system, permease component	321
647806495	314	43.87	5	314	7	316	2.0e-70	259	COG4605	ABC-type enterochelin transport system, permease component	316
647806496	250	46.99	1	249	1	249	1.0e-83	302	COG4604	ABC-type enterochelin transport system, ATPase component	252
647806497	239	40.68	178	236	5	63	1.0e-07	50.3	COG3411	(2Fe-2S) ferredoxin	64
647806498	322	24.91	27	297	29	288	4.0e-23	102	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
647806499	328	42.73	1	328	6	333	4.0e-50	192	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
647806500	260	37.9	5	244	1	248	3.0e-56	212	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
647806501	724	33.54	400	699	84	408	5.0e-38	153	COG0840	Methyl-accepting chemotaxis protein	408
647806502	279	25.27	11	279	1	243	5.0e-31	128	COG1360	Flagellar motor protein MotB	244
647806503	422	31.81	6	422	4	423	1.0e-53	204	COG1749	Flagellar hook protein FlgE	423
647806504	482	21.4	1	480	1	548	1.0e-38	154	COG1256	Flagellar hook-associated protein FlgK	552
647806505	335	15.1	10	335	7	357	1.0e-08	54.3	COG1344	Flagellin and related hook-associated protein FlgL	360
647806506	367	50.68	1	366	1	364	2.0e-106	379	COG1706	Flagellar basal body P-ring protein FlgI	365
647806507	248	43.9	1	246	5	248	5.0e-57	214	COG1338	Flagellar biosynthetic protein FliP	248
647806510	571	28.12	15	566	10	545	9.0e-75	274	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
647806511	185	25.88	23	184	9	158	7.0e-08	50.6	COG1580	Flagellar basal body-associated protein FliL	159
647806513	204	20.96	33	198	18	183	1.0e-05	43.1	COG3334	Flagellar motility protein MotE, a chaperone for MotC folding	192
647806514	289	34.74	1	285	3	265	7.0e-53	200	COG1291	Flagellar motor component MotA	266
647806516	679	40.27	3	677	27	693	0.0e+00	612	COG1298	Flagellar biosynthesis pathway, component FlhA	696
647806517	259	29.15	23	243	17	239	6.0e-25	107	COG1684	Flagellar biosynthesis protein FliR	258
647806518	363	36.01	2	362	1	358	9.0e-80	290	COG1377	Flagellar biosynthesis protein FlhB	363
647806521	223	41.44	40	220	55	230	3.0e-45	175	COG2063	Flagellar basal body L-ring protein FlgH	230
647806523	261	46.79	1	261	2	264	9.0e-72	263	COG4786	Flagellar basal body rod protein FlgG	265
647806524	238	32.43	6	235	6	264	4.0e-43	168	COG4786	Flagellar basal body rod protein FlgG	265
647806525	92	33.71	2	90	1	89	2.0e-08	50.9	COG1987	Flagellar biosynthesis protein FliQ	89
647806526	98	36.49	26	98	32	105	3.0e-08	49.9	COG1677	Flagellar hook-basal body complex protein FliE	105
647806527	130	36.96	1	129	1	137	2.0e-27	114	COG1558	Flagellar basal body rod protein FlgC	137
647806528	138	25.4	17	138	8	133	5.0e-15	73.8	COG1815	Flagellar basal body rod protein FlgB	133
647806529	447	42.99	4	441	3	440	1.0e-118	420	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
647806531	134	29.69	2	129	3	128	2.0e-15	74.6	COG5443	Flagellar biosynthesis regulator FlbT	148
647806532	123	27	21	119	17	115	1.0e-09	55.8	COG5442	Flagellar biosynthesis regulator FlaF	115
647806533	282	21.15	3	273	2	280	5.0e-16	78.6	COG1344	Flagellin and related hook-associated protein FlgL	360
647806537	231	25.69	5	219	3	220	4.0e-25	108	COG1843	Flagellar hook assembly protein FlgD	222
647806538	295	26.29	46	241	35	263	8.0e-08	51.2	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
647806539	435	24.81	35	420	1	387	1.0e-42	167	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647806540	272	49.24	2	262	7	267	2.0e-61	229	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
647806541	293	48.96	6	293	12	286	5.0e-73	267	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
647806542	379	49.18	17	379	1	352	2.0e-120	425	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
647806543	362	40.72	3	362	12	363	3.0e-86	312	COG0687	Spermidine/putrescine-binding periplasmic protein	363
647806544	228	32.89	4	226	1	224	4.0e-31	128	COG1802	DNA-binding transcriptional regulator, GntR family	230
647806545	465	44.49	10	456	2	449	0.0e+00	518	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
647806546	366	45.68	9	366	4	352	6.0e-111	394	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
647806547	368	22.49	6	365	11	362	1.0e-31	130	COG0687	Spermidine/putrescine-binding periplasmic protein	363
647806548	541	44.49	315	541	62	286	8.0e-65	241	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
647806549	391	37.55	127	387	14	267	1.0e-52	200	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
647806550	455	48.51	52	383	7	338	2.0e-86	313	COG2951	Membrane-bound lytic murein transglycosylase B	343
647806551	230	41.96	1	222	4	226	8.0e-44	170	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
647806552	237	21.21	13	237	5	204	2.0e-09	56.4	COG0625	Glutathione S-transferase	211
647806553	761	39.61	1	711	1	706	0.0e+00	579	COG0557	Exoribonuclease R	706
647806554	140	38.85	8	140	15	152	8.0e-23	99.6	COG2153	Predicted N-acyltransferase, GNAT family	155
647806555	381	30.38	5	381	14	408	3.0e-68	252	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647806560	247	29	16	244	2	231	2.0e-36	146	COG2188	DNA-binding transcriptional regulator, GntR family	236
647806562	454	27.39	1	440	3	420	1.0e-56	214	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
647806563	405	40.73	1	404	1	402	5.0e-88	318	COG1228	Imidazolonepropionase or related amidohydrolase	406
647806564	507	58.75	1	497	3	496	0.0e+00	592	COG2986	Histidine ammonia-lyase	498
647806565	258	46.51	3	255	10	266	2.0e-81	295	COG3741	N-formylglutamate amidohydrolase	272
647806566	560	75.89	1	560	2	557	0.0e+00	984	COG2987	Urocanate hydratase	561
647806567	129	32.84	12	128	1	133	6.0e-14	69.9	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
647806568	275	49.82	4	275	2	270	5.0e-85	307	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
647806570	208	32.7	1	207	4	214	2.0e-28	119	COG1802	DNA-binding transcriptional regulator, GntR family	230
647806571	317	37.94	7	307	12	322	2.0e-61	229	COG1171	Threonine dehydratase	347
647806572	282	39.72	64	273	9	200	2.0e-43	169	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
647806575	397	50.27	23	383	1	349	5.0e-115	407	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
647806578	335	39.76	4	331	7	338	5.0e-69	254	COG4448	L-asparaginase II	339
647806579	252	32.03	3	252	1	255	9.0e-12	64.3	COG0730	Uncharacterized membrane protein YfcA	258
647806580	291	46.19	74	283	3	212	7.0e-55	207	COG0560	Phosphoserine phosphatase	212
647806581	381	33.51	7	375	1	363	2.0e-99	356	COG1932	Phosphoserine aminotransferase	365
647806582	531	46.93	1	324	2	323	7.0e-94	338	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
647806584	348	35.13	6	345	1	350	1.0e-71	263	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
647806585	394	50.13	5	388	3	388	6.0e-124	437	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
647806587	391	40.84	1	391	1	392	2.0e-80	293	COG0183	Acetyl-CoA acetyltransferase	392
647806588	508	40.52	9	508	9	507	2.0e-119	423	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
647806589	250	49.37	13	250	1	238	3.0e-81	294	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
647806590	283	48.24	1	283	1	273	7.0e-92	330	COG0266	Formamidopyrimidine-DNA glycosylase	273
647806591	258	45.7	1	253	2	256	1.0e-59	223	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647806592	87	56.98	1	86	1	86	3.0e-14	69.9	COG0268	Ribosomal protein S20	88
647806593	470	42.73	6	466	1	408	4.0e-114	405	COG0593	Chromosomal replication initiation ATPase DnaA	408
647806594	373	41.82	1	373	1	364	3.0e-85	309	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
647806595	365	34.6	2	361	1	363	5.0e-73	268	COG1195	Recombinational DNA repair ATPase RecF	363
647806596	206	32.83	8	203	6	203	1.0e-15	76.5	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
647806597	195	27.38	1	168	2	169	1.0e-09	57	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647806598	217	27.04	24	216	1	187	2.0e-26	112	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
647806599	805	62.9	8	564	3	556	0.0e+00	879	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
647806600	271	42.6	51	271	2	224	1.0e-64	239	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
647806601	385	54.69	1	382	1	371	0.0e+00	460	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
647806602	641	62.15	1	603	4	579	0.0e+00	696	COG0443	Molecular chaperone DnaK (HSP70)	579
647806603	200	40.21	3	194	11	194	2.0e-34	139	COG3145	Alkylated DNA repair dioxygenase AlkB	194
647806604	273	16.8	2	255	1	249	1.0e-10	60.6	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
647806605	265	46.67	4	265	6	271	2.0e-67	249	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
647806606	266	37.31	1	265	2	247	1.0e-54	206	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
647806607	297	53.68	3	286	2	284	4.0e-110	391	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
647806608	327	48.61	4	324	3	325	1.0e-127	449	COG1087	UDP-glucose 4-epimerase	329
647806613	154	35.76	2	150	1	151	5.0e-26	110	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
647806614	187	32.14	1	110	1	110	4.0e-18	84.5	COG1544	Ribosome-associated translation inhibitor RaiA	110
647806615	252	64.85	15	251	5	243	1.0e-101	362	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
647806616	165	30.67	20	159	12	160	2.0e-19	88.4	COG1934	Lipopolysaccharide export system protein LptA	173
647806620	287	28.33	153	271	1	120	2.0e-18	86.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647806621	713	21.7	6	713	17	719	6.0e-51	195	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
647806623	228	33.95	14	223	2	216	5.0e-35	141	COG0569	Trk K+ transport system, NAD-binding component	225
647806624	448	32.29	20	444	68	499	5.0e-61	229	COG0168	Trk-type K+ transport system, membrane component	499
647806627	483	40.89	1	482	5	498	3.0e-114	405	COG1070	Sugar (pentulose or hexulose) kinase	502
647806628	436	67.58	1	436	1	438	0.0e+00	750	COG2115	Xylose isomerase	438
647806629	333	33.97	23	332	19	305	9.0e-44	170	COG2017	Galactose mutarotase or related enzyme	308
647806630	435	27.58	3	346	28	324	1.0e-37	151	COG1858	Cytochrome c peroxidase	364
647806631	516	30.99	8	458	4	403	1.0e-57	217	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
647806632	401	29.18	1	389	3	402	6.0e-33	135	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
647806633	256	52.85	2	246	1	245	2.0e-87	316	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
647806634	285	53.05	4	278	1	276	1.0e-97	349	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
647806635	305	55	23	301	6	285	2.0e-75	275	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647806636	330	41.98	5	328	9	312	2.0e-78	285	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647806637	532	27.34	3	516	13	537	2.0e-66	247	COG0747	ABC-type transport system, periplasmic component	556
647806638	349	41.74	6	349	3	313	4.0e-77	281	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
647806639	158	39.87	1	153	3	154	5.0e-32	130	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647806640	346	38.33	1	346	4	338	1.0e-89	323	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
647806641	536	44.53	13	524	11	502	3.0e-128	452	COG1292	Choline-glycine betaine transporter	537
647806642	218	27.57	1	213	8	216	1.0e-18	86.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
647806643	480	34.27	22	475	31	485	3.0e-82	299	COG1953	Cytosine/uracil/thiamine/allantoin permease	497
647806644	567	44.27	1	567	3	563	0.0e+00	492	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647806646	398	32.68	1	393	1	408	1.0e-87	317	COG2081	Predicted flavoprotein YhiN	408
647806647	196	27.94	2	193	1	203	6.0e-20	91	COG0625	Glutathione S-transferase	211
647806648	342	25.15	22	340	19	334	6.0e-19	88.5	COG1466	DNA polymerase III, delta subunit	334
647806649	177	21.94	20	167	15	167	1.0e-05	43.5	COG5468	Predicted secreted (periplasmic) protein	172
647806650	881	45.25	1	881	2	814	0.0e+00	908	COG0495	Leucyl-tRNA synthetase	814
647806653	218	45.33	1	216	5	228	1.0e-66	246	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
647806655	362	56.84	173	362	6	193	9.0e-61	227	COG0807	GTP cyclohydrolase II	193
647806656	228	44.35	5	228	1	227	2.0e-50	192	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647806658	262	36.84	5	262	3	261	4.0e-68	251	COG0708	Exonuclease III	261
647806660	311	40.32	1	310	8	304	6.0e-60	224	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
647806661	214	40.28	1	211	2	215	4.0e-39	154	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
647806662	61	56.6	9	61	2	54	4.0e-13	66.4	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
647806663	405	42.96	1	394	2	387	8.0e-74	271	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647806664	443	37.61	1	442	1	467	4.0e-85	308	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
647806665	392	31.49	10	391	7	389	1.0e-63	237	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
647806666	994	34.59	289	994	206	856	0.0e+00	472	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
647806667	198	22.28	1	195	5	203	6.0e-18	84.3	COG2834	Outer membrane lipoprotein-sorting protein	211
647806668	256	45.74	69	252	11	194	7.0e-52	197	COG4764	Uncharacterized protein	197
647806669	108	61.39	6	106	13	113	2.0e-33	134	COG3785	Heat shock protein HspQ	116
647806670	525	38.3	11	525	11	539	0.0e+00	461	COG0405	Gamma-glutamyltranspeptidase	539
647806671	146	23.44	8	134	9	131	1.0e-15	75.8	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
647806672	114	32.11	1	107	3	111	7.0e-10	55.8	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
647806673	390	42.22	1	389	1	391	6.0e-75	274	COG0183	Acetyl-CoA acetyltransferase	392
647806674	156	47.92	4	147	15	156	5.0e-42	163	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
647806675	209	24.64	1	201	1	207	2.0e-15	76.1	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
647806676	126	41.73	3	126	2	128	3.0e-25	107	COG3791	Uncharacterized conserved protein	133
647806677	311	46.37	9	297	4	292	4.0e-78	285	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
647806678	118	27.43	4	116	7	109	7.0e-07	45.8	COG3895	Membrane-bound inhibitor of C-type lysozyme	112
647806679	217	42.22	1	217	65	289	9.0e-56	209	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
647806680	237	30.65	110	232	2	125	2.0e-16	79.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647806681	518	43.74	45	511	3	465	5.0e-129	454	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647806682	216	38.05	1	198	1	194	6.0e-53	200	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
647806683	288	25.89	1	265	2	283	4.0e-32	131	COG1216	Glycosyltransferase, GT2 family	305
647806684	712	60.14	1	697	1	692	0.0e+00	948	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
647806686	404	39.47	6	375	1	321	2.0e-85	309	COG0523	GTPase, G3E family	323
647806687	652	19.13	10	652	37	768	2.0e-21	97.7	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647806688	89	61.8	1	89	1	89	2.0e-27	113	COG0184	Ribosomal protein S15P/S13E	89
647806689	284	25.36	13	284	7	280	7.0e-16	78.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647806692	185	34.55	14	178	3	165	7.0e-31	127	COG4333	Uncharacterized protein	167
647806693	302	38.74	3	301	4	271	1.0e-64	240	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
647806694	257	45.27	3	245	9	248	2.0e-66	246	COG3698	Uncharacterized protein YigE, DUF2233 family	250
647806695	131	32.77	12	128	3	118	2.0e-17	81.4	COG0858	Ribosome-binding factor A	118
647806696	269	54.37	7	269	5	266	5.0e-80	290	COG0289	Dihydrodipicolinate reductase	266
647806697	64	52.38	3	64	22	84	4.0e-11	59.7	COG5508	Uncharacterized protein	84
647806698	436	34.18	107	433	3	353	9.0e-67	248	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
647806700	581	31.11	27	561	40	564	4.0e-72	266	COG5360	Uncharacterized conserved protein, heparinase superfamily	566
647806701	529	60.76	6	529	1	515	0.0e+00	739	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
647806702	160	30.07	6	158	13	160	7.0e-19	86.8	COG0597	Lipoprotein signal peptidase	167
647806704	477	32.32	55	476	16	436	2.0e-72	266	COG0612	Predicted Zn-dependent peptidase	438
647806705	457	29.82	30	457	3	438	4.0e-71	262	COG0612	Predicted Zn-dependent peptidase	438
647806706	780	45.69	33	482	1	463	1.0e-125	444	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647806707	354	33.84	82	343	1	227	9.0e-55	207	COG0274	Deoxyribose-phosphate aldolase	228
647806708	320	31.82	1	304	1	302	7.0e-57	214	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
647806709	267	50.62	23	261	5	245	7.0e-83	300	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
647806710	400	38.38	19	289	19	274	2.0e-41	163	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
647806711	308	30.14	10	301	15	272	5.0e-28	118	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
647806712	643	44.5	22	642	2	637	0.0e+00	632	COG0323	DNA mismatch repair ATPase MutL	638
647806713	411	28.42	13	393	34	413	4.0e-55	209	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
647806714	438	25.11	204	426	1	211	1.0e-23	104	COG2114	Adenylate cyclase, class 3	227
647806716	380	21.64	24	349	26	353	7.0e-31	128	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
647806717	350	24.01	9	331	8	326	6.0e-13	68.7	COG0686	Alanine dehydrogenase	371
647806718	204	33.17	1	200	1	203	1.0e-27	116	COG0625	Glutathione S-transferase	211
647806719	218	25.12	1	209	2	208	1.0e-16	80.3	COG0406	Broad specificity phosphatase PhoE	208
647806721	239	36.96	8	235	1	228	1.0e-43	169	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647806722	634	28.63	275	515	93	336	4.0e-21	96.8	COG0642	Signal transduction histidine kinase	336
647806723	661	31.46	1	621	1	611	1.0e-121	430	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
647806724	261	47.01	8	258	3	250	7.0e-87	314	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
647806725	328	27.78	5	327	3	297	2.0e-32	133	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
647806728	358	31.78	31	350	10	314	1.0e-37	150	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
647806729	427	18.37	15	391	3	359	4.0e-14	73.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
647806730	278	52.05	13	256	1	237	5.0e-81	294	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
647806731	405	30.79	1	392	9	422	4.0e-50	192	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
647806733	559	32.43	19	559	5	536	3.0e-74	273	COG1178	ABC-type Fe3+ transport system, permease component	540
647806734	287	29.6	3	250	1	275	4.0e-43	168	COG0523	GTPase, G3E family	323
647806735	336	28.16	38	335	1	298	4.0e-43	168	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
647806738	311	37.32	26	301	1	262	4.0e-56	211	COG3741	N-formylglutamate amidohydrolase	272
647806739	378	45.8	2	339	7	351	8.0e-80	291	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
647806740	139	25.93	5	136	12	143	5.0e-08	50.4	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
647806742	243	41.74	6	233	10	235	3.0e-44	172	COG0284	Orotidine-5'-phosphate decarboxylase	240
647806743	872	55.56	5	854	1	781	0.0e+00	955	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
647806744	496	27.07	25	478	21	485	2.0e-85	310	COG0069	Glutamate synthase domain 2	485
647806745	302	48.4	56	273	66	269	5.0e-57	214	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
647806746	199	45.74	14	199	11	198	5.0e-37	147	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
647806757	567	36.79	31	567	6	551	6.0e-124	438	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
647806758	223	46.02	1	221	1	225	5.0e-57	214	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647806759	454	27.53	140	452	21	327	4.0e-31	129	COG0642	Signal transduction histidine kinase	336
647806762	299	28.57	173	291	2	120	4.0e-21	95.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647806763	693	25.17	11	690	26	745	9.0e-58	218	COG4774	Outer membrane receptor for monomeric catechols	750
647806764	340	25.16	14	324	8	308	6.0e-30	124	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
647806765	348	47.15	20	346	1	332	2.0e-54	206	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
647806766	349	44.82	20	345	18	345	2.0e-54	206	COG4779	ABC-type enterobactin transport system, permease component	346
647806767	278	53.91	10	265	3	258	6.0e-92	330	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
647806768	498	21.54	187	497	7	327	2.0e-31	130	COG0642	Signal transduction histidine kinase	336
647806769	230	46.7	4	226	2	227	7.0e-59	220	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647806771	345	62.08	20	344	13	339	1.0e-130	459	COG4150	ABC-type sulfate transport system, periplasmic component	341
647806772	280	55.56	6	275	3	272	1.0e-64	240	COG0555	ABC-type sulfate transport system, permease component	274
647806773	266	56.03	2	258	19	275	7.0e-81	293	COG4208	ABC-type sulfate transport system, permease component	287
647806775	185	24.21	1	185	1	186	1.0e-07	50	COG3009	Uncharacterized lipoprotein YmbA	190
647806776	677	30.42	3	494	18	501	8.0e-80	292	COG3008	Paraquat-inducible protein B	553
647806781	458	50.33	1	446	1	447	0.0e+00	480	COG1115	Na+/alanine symporter	452
647806782	506	27.18	7	497	2	472	2.0e-64	240	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647806783	229	39.11	1	224	6	229	1.0e-33	136	COG1802	DNA-binding transcriptional regulator, GntR family	230
647806784	342	40.41	9	340	4	339	5.0e-82	298	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
647806786	495	48.74	19	494	3	469	0.0e+00	491	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647806787	292	32.4	1	287	1	285	2.0e-48	186	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
647806788	362	43.73	35	360	2	328	5.0e-88	317	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647806789	175	29.94	1	167	5	171	4.0e-23	101	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647806790	427	51.44	46	426	1	379	4.0e-87	315	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647806791	435	52.02	1	435	1	446	4.0e-122	431	COG2031	Short chain fatty acids transporter	446
647806792	270	27.44	4	256	3	254	5.0e-23	101	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
647806793	340	45.98	3	338	6	351	1.0e-100	360	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
647806794	262	29.62	3	259	7	264	9.0e-30	124	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
647806795	267	34.47	9	267	14	274	4.0e-33	135	COG0555	ABC-type sulfate transport system, permease component	274
647806796	339	29.04	46	339	1	297	3.0e-38	152	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
647806797	362	37.31	7	336	1	333	1.0e-64	240	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
647806798	155	40.14	1	146	9	152	6.0e-29	120	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
647806801	343	34.01	1	340	1	333	5.0e-62	231	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
647806802	449	17.43	51	448	33	429	2.0e-18	87.4	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
647806803	335	35.69	43	335	2	292	2.0e-51	196	COG1175	ABC-type sugar transport system, permease component	295
647806804	382	37.19	142	382	45	281	3.0e-49	189	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
647806805	550	39.61	23	518	1	495	1.0e-100	360	COG0366	Glycosidase	505
647806806	365	52.26	1	354	1	335	1.0e-114	406	COG3839	ABC-type sugar transport system, ATPase component	338
647806816	645	35.47	1	532	7	542	2.0e-116	413	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
647806817	231	24.4	1	207	6	191	8.0e-12	64.1	COG0684	Regulator of RNase E activity RraA	210
647806818	231	25.19	1	231	21	282	6.0e-13	68.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647806822	344	35.14	5	335	1	330	2.0e-70	259	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
647806823	254	36.47	10	252	1	251	8.0e-38	150	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647806825	443	40.38	6	426	13	425	3.0e-117	415	COG0141	Histidinol dehydrogenase	425
647806826	183	28.68	17	152	2	131	1.0e-09	56.1	COG5485	Predicted ester cyclase	131
647806828	384	33.57	107	383	12	281	9.0e-38	151	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
647806829	340	24.85	1	340	7	295	2.0e-27	117	COG1175	ABC-type sugar transport system, permease component	295
647806830	402	20.99	1	390	3	425	1.0e-13	71.6	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
647806831	348	53.06	1	343	1	338	1.0e-121	429	COG3839	ABC-type sugar transport system, ATPase component	338
647806835	219	24.76	11	201	1	203	8.0e-15	74.1	COG0625	Glutathione S-transferase	211
647806840	128	36.28	16	127	13	122	7.0e-14	69.7	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
647806841	326	40.38	1	313	1	315	2.0e-81	296	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
647806842	311	26.78	15	300	3	297	3.0e-23	102	COG0583	DNA-binding transcriptional regulator, LysR family	297
647806843	210	26.94	1	190	29	210	2.0e-11	62.6	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
647806844	311	48.2	4	308	2	302	3.0e-89	321	COG4589	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase	303
647806846	215	25.26	20	211	3	185	2.0e-09	55.8	COG0558	Phosphatidylglycerophosphate synthase	192
647806847	109	21.74	2	109	1	112	1.0e-06	45.1	COG3293	Transposase	124
647806848	251	24.21	1	249	2	252	4.0e-06	45.4	COG0730	Uncharacterized membrane protein YfcA	258
647806855	427	22.6	35	418	39	445	2.0e-27	117	COG1538	Outer membrane protein TolC	457
647806856	715	32.28	9	700	9	697	0.0e+00	508	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
647806857	379	21.18	5	319	7	293	2.0e-16	80.4	COG1566	Multidrug resistance efflux pump	352
647806859	412	18.92	5	406	2	381	4.0e-19	89.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647806860	212	37.8	10	212	2	209	9.0e-37	147	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
647806868	652	47.76	9	652	1	635	0.0e+00	804	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
647806869	202	32.06	49	178	46	172	6.0e-13	67.9	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
647806870	212	20.85	7	210	11	213	9.0e-11	60.7	COG3683	ABC-type uncharacterized transport system, periplasmic component	213
647806871	327	31.43	10	324	4	298	3.0e-36	145	COG2215	ABC-type nickel/cobalt efflux system, permease component RcnA	303
647806872	472	37.59	17	453	17	447	4.0e-63	235	COG0534	Na+-driven multidrug efflux pump	455
647806875	408	46.9	16	407	3	392	8.0e-117	413	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
647806877	92	30.12	10	92	9	90	4.0e-13	66.4	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
647806878	165	26.36	28	155	1	126	3.0e-07	48	COG1846	DNA-binding transcriptional regulator, MarR family	126
647806882	248	57.44	7	248	3	240	1.0e-93	336	COG1126	ABC-type polar amino acid transport system, ATPase component	240
647806883	224	42.52	9	222	11	222	6.0e-50	190	COG0765	ABC-type amino acid transport system, permease component	222
647806884	277	34.19	28	277	1	271	4.0e-39	155	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
647806885	274	23.92	66	263	25	233	5.0e-12	65.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
647806886	127	21.43	8	126	10	134	4.0e-09	53.7	COG0848	Biopolymer transport protein ExbD	137
647806887	126	29.82	16	125	18	131	2.0e-09	54.8	COG0848	Biopolymer transport protein ExbD	137
647806888	321	34.39	124	302	13	200	2.0e-20	93.5	COG0811	Biopolymer transport protein ExbB/TolQ	216
647806889	356	27.2	110	348	13	259	4.0e-28	118	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
647806890	260	50.59	5	259	1	255	5.0e-90	324	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
647806891	344	41.23	2	341	7	345	2.0e-50	193	COG4779	ABC-type enterobactin transport system, permease component	346
647806892	342	39.7	14	341	1	333	2.0e-45	176	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
647806893	334	28.72	38	312	48	319	6.0e-30	125	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
647806895	221	24.77	1	214	5	210	6.0e-18	84.4	COG1802	DNA-binding transcriptional regulator, GntR family	230
647806896	338	22.55	5	337	7	329	1.0e-23	104	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
647806897	255	47.56	3	248	4	248	6.0e-79	287	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
647806898	269	38.58	15	268	1	254	6.0e-49	187	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
647806899	296	31.53	77	294	2	221	3.0e-28	119	COG1910	Periplasmic molybdate-binding protein/domain	223
647806900	273	45.02	2	272	7	275	7.0e-76	277	COG2998	ABC-type tungstate transport system, permease component	280
647806901	252	34.47	25	247	3	237	1.0e-45	176	COG1126	ABC-type polar amino acid transport system, ATPase component	240
647806902	235	45.37	11	226	10	225	2.0e-43	168	COG4662	ABC-type tungstate transport system, periplasmic component	227
647806905	367	55.68	1	366	1	348	1.0e-120	426	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
647806910	709	18.31	85	709	99	768	4.0e-30	126	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647806913	305	29.11	11	301	5	287	5.0e-24	105	COG0583	DNA-binding transcriptional regulator, LysR family	297
647806914	351	48.14	3	350	4	338	2.0e-109	389	COG4213	ABC-type xylose transport system, periplasmic component	341
647806915	506	51.29	1	503	5	497	0.0e+00	599	COG1129	ABC-type sugar transport system, ATPase component	500
647806916	411	50	6	410	5	394	1.0e-106	379	COG4214	ABC-type xylose transport system, permease component	394
647806917	580	43.36	11	568	10	574	0.0e+00	640	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
647806918	307	19.16	1	306	4	337	4.0e-22	98.8	COG0673	Predicted dehydrogenase	342
647806919	305	28.04	1	290	1	287	4.0e-42	165	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
647806920	497	27.71	2	489	5	472	7.0e-60	225	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647806921	299	40.73	1	294	2	302	2.0e-57	216	COG3734	2-keto-3-deoxy-galactonokinase	306
647806922	201	34	1	200	11	209	2.0e-44	172	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
647806923	284	37.5	1	282	12	307	2.0e-56	212	COG3386	Sugar lactone lactonase YvrE	307
647806924	538	36.41	1	537	3	562	2.0e-108	386	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
647806925	305	41.01	1	305	1	315	1.0e-77	283	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647806926	304	42.36	17	304	6	287	1.0e-66	246	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647806927	322	54.55	3	317	1	316	1.0e-122	432	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
647806928	332	43.37	4	324	1	316	5.0e-94	337	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
647806929	202	24.73	3	184	1	180	1.0e-11	63.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647806930	353	43.32	8	342	14	340	8.0e-72	264	COG1566	Multidrug resistance efflux pump	352
647806932	206	33.33	26	206	23	205	1.0e-22	99	COG3932	Uncharacterized conserved protein	209
647806936	175	54.86	2	175	1	170	2.0e-48	185	COG4675	Microcystin-dependent protein  (function unknown)	170
647806937	172	51.74	2	171	1	169	3.0e-50	190	COG4675	Microcystin-dependent protein  (function unknown)	170
647806938	181	55.29	15	181	1	170	1.0e-52	199	COG4675	Microcystin-dependent protein  (function unknown)	170
647806944	304	26.35	7	297	1	292	2.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
647806945	358	27.03	1	358	1	363	1.0e-41	164	COG0687	Spermidine/putrescine-binding periplasmic protein	363
647806946	370	48.48	6	365	4	352	1.0e-106	380	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
647806947	288	34.72	11	272	10	273	2.0e-51	196	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
647806948	286	31.79	6	284	4	263	1.0e-37	150	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
647806949	258	40.08	12	255	14	257	4.0e-50	191	COG0725	ABC-type molybdate transport system, periplasmic component	258
647806950	231	58.3	7	228	3	224	2.0e-60	226	COG4149	ABC-type molybdate transport system, permease component	225
647806951	363	47.46	5	355	4	352	6.0e-96	344	COG4148	ABC-type molybdate transport system, ATPase component	352
647806952	226	44.4	1	223	3	234	1.0e-55	210	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
647806953	196	34.25	1	196	2	213	3.0e-15	75	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
647806954	179	48.88	1	178	5	179	1.0e-25	109	COG1268	Biotin transporter BioY	184
647806955	269	32.78	26	265	1	240	4.0e-34	138	COG1414	DNA-binding transcriptional regulator, IclR family	246
647806956	498	39.22	1	484	1	472	6.0e-106	378	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
647806957	534	24.01	1	529	6	547	1.0e-61	231	COG0747	ABC-type transport system, periplasmic component	556
647806958	313	47.62	1	313	1	315	1.0e-87	316	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647806959	295	46.18	9	293	2	289	1.0e-61	230	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647806960	561	52.42	10	539	1	535	0.0e+00	628	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
647806961	388	46.89	9	388	9	392	2.0e-115	409	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
647806962	380	23.12	14	379	14	407	4.0e-26	112	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647806963	258	38.27	11	251	6	248	1.0e-42	166	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
647806964	242	38.49	12	242	10	246	2.0e-51	195	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
647806965	225	38.14	12	223	7	215	2.0e-46	178	COG0819	Thiaminase	218
647806966	311	32.48	4	304	13	319	2.0e-38	153	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
647806967	318	44.65	1	210	8	222	5.0e-50	191	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
647806968	198	37.82	6	198	17	207	8.0e-50	190	COG0352	Thiamine monophosphate synthase	211
647806969	256	52.53	1	256	7	262	6.0e-91	327	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
647806970	64	43.94	1	64	3	68	1.0e-09	55.2	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
647806971	324	27.98	6	313	9	367	4.0e-26	112	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647806972	267	56.65	4	265	5	263	1.0e-89	322	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
647806973	487	40.9	17	481	2	466	5.0e-126	444	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647806974	321	29.73	16	310	1	290	2.0e-31	129	COG0583	DNA-binding transcriptional regulator, LysR family	297
647806975	260	39.54	1	258	1	252	1.0e-52	199	COG1712	Predicted dinucleotide-utilizing enzyme	255
647806976	317	28.1	16	317	5	297	1.0e-39	157	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
647806979	326	32.19	10	326	14	332	2.0e-52	199	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647806980	179	25.16	11	168	14	152	2.0e-12	65.7	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647806981	419	44.53	44	418	1	374	1.0e-81	297	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647806995	400	28.88	4	397	1	408	4.0e-54	205	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647806996	494	43.03	1	492	3	497	2.0e-116	413	COG3333	TctA family transporter	504
647806998	323	34.46	1	321	1	318	3.0e-49	188	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
647806999	303	27.46	2	293	1	291	6.0e-26	111	COG0583	DNA-binding transcriptional regulator, LysR family	297
647807000	336	41.27	14	328	4	309	3.0e-46	179	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
647807001	500	43.84	1	491	5	496	0.0e+00	527	COG1129	ABC-type sugar transport system, ATPase component	500
647807002	356	27.3	52	339	28	317	4.0e-26	112	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
647807003	323	43.34	3	323	1	311	4.0e-87	314	COG1984	Allophanate hydrolase subunit 2	314
647807004	291	34.55	5	250	1	219	4.0e-52	198	COG2049	Allophanate hydrolase subunit 1	223
647807007	286	45.38	32	278	4	250	5.0e-81	294	COG1540	Lactam utilization protein B (function unknown)	252
647807008	305	30.17	1	292	1	290	4.0e-40	158	COG0583	DNA-binding transcriptional regulator, LysR family	297
647807010	425	51.04	1	423	16	447	0.0e+00	504	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
647807011	489	47.35	17	485	1	467	0.0e+00	531	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647807012	344	25.67	7	344	3	401	9.0e-43	167	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
647807013	211	22.49	7	211	3	208	2.0e-26	112	COG1186	Protein chain release factor B	239
647807017	557	24.07	108	518	4	421	3.0e-18	87	COG1404	Serine protease, subtilisin family	508
647807018	224	27.6	1	216	1	211	2.0e-23	102	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
647807024	124	26.47	1	102	9	110	2.0e-07	48.3	COG0640	DNA-binding transcriptional regulator, ArsR family	110
647807025	148	26.39	1	138	6	149	9.0e-16	76.3	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
647807026	577	31.11	2	567	1	547	4.0e-95	342	COG0659	Sulfate permease or related transporter, MFS superfamily	554
647807027	559	46.92	1	129	1	130	1.0e-34	141	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
647807028	294	21.43	8	253	8	250	3.0e-22	99.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647807032	221	25.12	6	211	1	213	7.0e-24	104	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
647807033	512	48.75	43	476	2	440	0.0e+00	484	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
647807034	333	43.02	1	333	3	345	2.0e-70	259	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
647807035	539	44.96	4	533	1	528	0.0e+00	553	COG1069	Ribulose kinase	544
647807037	282	22.85	4	253	1	265	4.0e-29	122	COG1082	Sugar phosphate isomerase/epimerase	274
647807038	336	37.86	20	327	11	313	3.0e-45	176	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
647807039	330	34.47	5	325	4	316	6.0e-46	178	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
647807040	501	47.31	3	501	1	499	0.0e+00	546	COG1129	ABC-type sugar transport system, ATPase component	500
647807041	335	28.75	1	310	2	313	5.0e-40	158	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
647807042	342	27.98	10	337	2	323	1.0e-47	184	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
647807044	542	55.12	1	531	3	537	0.0e+00	658	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
647807045	279	50.18	1	277	11	289	3.0e-66	245	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647807046	323	46.42	1	321	1	315	1.0e-86	313	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647807047	524	31.69	1	524	7	555	4.0e-80	292	COG0747	ABC-type transport system, periplasmic component	556
647807048	253	34.1	34	247	8	223	3.0e-34	138	COG1802	DNA-binding transcriptional regulator, GntR family	230
647807049	342	31.99	1	337	4	309	4.0e-52	199	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
647807051	445	23.24	1	445	69	530	2.0e-51	197	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
647807052	429	26.39	9	423	2	408	4.0e-44	172	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647807053	369	30.21	27	355	1	321	8.0e-45	174	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
647807054	441	37.92	2	439	1	447	2.0e-120	426	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
647807055	379	22.57	20	358	12	354	3.0e-23	103	COG0628	Predicted PurR-regulated permease PerM	355
647807057	158	43.92	8	155	6	152	8.0e-31	126	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647807058	1131	47.96	434	1127	9	766	0.0e+00	735	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
647807059	256	36.4	1	222	2	221	9.0e-27	114	COG0705	Membrane associated serine protease, rhomboid family	228
647807060	128	27.73	1	115	1	117	3.0e-16	77.4	COG3791	Uncharacterized conserved protein	133
647807061	261	44.53	7	260	5	260	3.0e-65	242	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
647807062	301	30.23	3	301	1	297	1.0e-32	134	COG0583	DNA-binding transcriptional regulator, LysR family	297
647807063	289	40.21	4	279	15	289	1.0e-63	236	COG0685	5,10-methylenetetrahydrofolate reductase	291
647807064	160	28.46	28	157	10	138	2.0e-19	88.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
647807065	337	23.19	31	288	6	273	7.0e-09	55	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
647807068	769	34.08	12	763	8	731	0.0e+00	497	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
647807069	1047	42.36	22	1045	1	877	0.0e+00	1004	COG0525	Valyl-tRNA synthetase	877
647807070	97	42.71	1	95	1	96	1.0e-21	94.6	COG5470	Uncharacterized conserved protein, DUF1330 family	96
647807071	156	22.07	1	142	6	147	2.0e-07	48.4	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
647807072	147	34.04	3	143	7	147	1.0e-14	72.3	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
647807075	259	60.32	6	256	5	256	2.0e-100	358	COG4598	ABC-type histidine transport system, ATPase component	256
647807076	235	29.96	4	229	17	262	1.0e-27	116	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
647807077	260	32.38	2	245	20	228	2.0e-35	142	COG4215	ABC-type arginine transport system, permease component	230
647807078	268	33.94	35	252	12	226	5.0e-36	144	COG4160	ABC-type arginine/histidine transport system, permease component	228
647807079	585	44.74	125	580	2	444	1.0e-126	447	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
647807080	423	42.93	5	413	1	415	4.0e-103	368	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
647807082	302	24.12	13	238	23	279	2.0e-14	73.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647807083	141	25.2	8	124	7	126	3.0e-08	51.1	COG3607	Predicted lactoylglutathione lyase	133
647807086	648	52.37	36	647	1	585	0.0e+00	733	COG0441	Threonyl-tRNA synthetase	589
647807087	101	52.94	3	80	10	94	4.0e-14	69.8	COG5572	Uncharacterized membrane protein	104
647807088	286	47.01	11	276	3	266	1.0e-84	306	COG3220	Uncharacterized conserved protein, UPF0276 family	282
647807091	105	29.91	1	97	3	109	8.0e-15	72.1	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
647807092	68	58.82	1	68	1	67	3.0e-21	93.7	COG1278	Cold shock protein, CspA family	67
647807093	160	42.07	1	137	1	145	7.0e-31	126	COG0262	Dihydrofolate reductase	167
647807094	277	60.93	1	277	3	268	3.0e-107	381	COG0207	Thymidylate synthase	268
647807095	142	27.54	3	122	1	138	1.0e-11	62.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
647807104	219	36.02	11	219	5	212	7.0e-22	97.6	COG0368	Cobalamin synthase	246
647807105	336	45.05	10	334	2	334	3.0e-73	269	COG2038	NaMN:DMB phosphoribosyltransferase	347
647807106	625	35.48	1	414	4	393	2.0e-57	217	COG0475	Kef-type K+ transport system, membrane component KefB	397
647807108	156	39.47	5	156	4	154	2.0e-30	125	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647807109	366	49.18	4	366	3	363	2.0e-119	422	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
647807111	238	35.04	7	232	12	242	3.0e-35	141	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
647807112	430	56.64	7	428	6	426	0.0e+00	598	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
647807115	147	38.28	24	145	31	158	5.0e-21	93.6	COG2030	Acyl dehydratase	159
647807117	291	29.06	8	268	1	252	2.0e-39	156	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
647807118	681	34.21	2	489	37	513	3.0e-94	339	COG0513	Superfamily II DNA and RNA helicase	513
647807119	174	33.04	44	157	12	125	1.0e-11	63.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
647807120	224	32.86	82	221	11	145	2.0e-17	82.8	COG4335	3-methyladenine DNA glycosylase AlkC	167
647807123	306	38.94	3	304	4	304	2.0e-61	229	COG1227	Inorganic pyrophosphatase/exopolyphosphatase	311
647807125	302	27.93	11	298	17	296	2.0e-27	116	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
647807126	316	29.27	29	313	22	297	7.0e-35	141	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
647807127	232	43.72	7	219	3	214	5.0e-50	190	COG5482	Uncharacterized protein	229
647807128	95	61.7	1	94	1	94	2.0e-30	124	COG0234	Co-chaperonin GroES (HSP10)	96
647807129	547	50.18	1	535	1	524	0.0e+00	507	COG0459	Chaperonin GroEL (HSP60 family)	524
647807133	385	34.38	26	363	17	363	3.0e-51	196	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
647807134	365	51.43	11	356	1	350	2.0e-123	436	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
647807135	162	63.69	5	161	4	158	4.0e-57	213	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
647807136	308	33.78	13	302	1	291	2.0e-44	173	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
647807137	152	31.01	21	147	3	129	3.0e-16	77.8	COG3791	Uncharacterized conserved protein	133
647807141	137	37.8	14	135	21	146	4.0e-22	97	COG0071	Molecular chaperone IbpA, HSP20 family	146
647807142	74	53.33	15	74	9	67	2.0e-07	47.3	COG5481	Uncharacterized protein	67
647807143	572	44.92	26	398	24	387	4.0e-115	408	COG2046	ATP sulfurylase (sulfate adenylyltransferase)	397
647807144	560	31.18	363	547	45	217	1.0e-22	101	COG2114	Adenylate cyclase, class 3	227
647807145	331	52.09	23	331	2	304	2.0e-90	325	COG0492	Thioredoxin reductase	305
647807146	166	38.71	1	155	1	154	6.0e-33	133	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647807149	255	40.39	1	255	1	247	8.0e-64	237	COG1496	Copper oxidase (laccase) domain	249
647807150	357	39.4	1	355	2	367	5.0e-79	288	COG1565	SAM-dependent methyltransferase, MidA family	370
647807151	302	37.54	1	293	1	274	1.0e-58	220	COG0682	Prolipoprotein diacylglyceryltransferase	287
647807152	83	37.35	1	83	8	90	2.0e-11	60.8	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
647807153	166	33.73	1	166	1	166	1.0e-31	129	COG5465	Uncharacterized protein	166
647807154	275	47.19	15	274	4	265	2.0e-58	219	COG0345	Pyrroline-5-carboxylate reductase	266
647807155	116	33.63	1	107	8	119	5.0e-15	73.1	COG0073	tRNA-binding EMAP/Myf domain	123
647807156	322	41.74	9	322	5	321	2.0e-76	279	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
647807157	200	37.31	1	192	3	195	6.0e-66	243	COG1435	Thymidine kinase	201
647807160	248	33.5	41	235	1	184	6.0e-35	141	COG0431	NAD(P)H-dependent FMN reductase	184
647807161	374	28.61	1	371	1	321	1.0e-67	250	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
647807162	160	37.14	42	142	20	124	2.0e-07	49.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
647807163	353	22.83	1	346	6	366	9.0e-16	77.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
647807164	1017	26.41	2	1004	1	1008	0.0e+00	670	COG0841	Multidrug efflux pump subunit AcrB	1009
647807165	1120	65.44	13	420	1	393	0.0e+00	553	COG0458	Carbamoylphosphate synthase large subunit	400
647807166	375	37.23	19	366	78	449	5.0e-89	321	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
647807167	215	26.94	27	215	42	260	5.0e-22	97.8	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
647807168	594	49.66	4	592	1	585	0.0e+00	807	COG0173	Aspartyl-tRNA synthetase	585
647807173	91	30	1	80	1	80	9.0e-08	48.8	COG5454	Predicted secreted protein	89
647807174	384	22.97	76	367	4	296	3.0e-20	93.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
647807175	113	37.5	2	113	17	125	8.0e-25	105	COG2343	Uncharacterized conserved protein, DUF427 family	132
647807176	594	26.49	150	522	1	367	1.0e-49	191	COG0006	Xaa-Pro aminopeptidase	384
647807177	625	52.53	1	608	11	618	0.0e+00	594	COG4547	Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib...	620
647807178	233	23.79	3	222	4	229	9.0e-19	87.2	COG1794	Aspartate/glutamate racemase	230
647807179	328	19.21	20	312	1	289	4.0e-38	152	COG0714	MoxR-like ATPase	329
647807182	84	55.13	4	80	5	79	4.0e-16	76.2	COG0271	Stress-induced morphogen (activity unknown)	90
647807184	414	36.03	12	412	10	414	1.0e-77	284	COG2195	Di- or tripeptidase	414
647807186	467	33.04	27	466	3	435	1.0e-117	417	COG0621	tRNA A37 methylthiotransferase MiaB	437
647807187	680	17.53	31	638	3	646	1.0e-30	128	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
647807188	498	28.9	18	490	2	462	2.0e-77	283	COG1109	Phosphomannomutase	464
647807189	277	58.03	1	274	2	275	2.0e-118	418	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
647807190	532	23.82	191	529	32	370	2.0e-31	130	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
647807191	219	27.73	1	216	24	241	5.0e-40	157	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
647807192	222	28.06	30	218	13	202	1.0e-36	146	COG1573	Uracil-DNA glycosylase	202
647807194	290	28.5	47	254	4	200	4.0e-26	112	COG0625	Glutathione S-transferase	211
647807198	209	41.35	1	207	1	208	2.0e-23	103	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
647807199	297	29.41	172	289	2	120	1.0e-14	74.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647807200	127	24.27	19	121	26	127	2.0e-14	71.6	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
647807201	136	69.4	3	136	2	135	3.0e-52	197	COG4954	Uncharacterized protein	135
647807202	196	44.85	1	192	1	166	1.0e-34	139	COG5352	Uncharacterized protein	169
647807203	274	22	23	267	16	253	3.0e-10	59.4	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
647807204	308	21.83	11	288	6	289	3.0e-07	49.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
647807205	391	54.1	5	391	17	402	0.0e+00	483	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
647807206	308	50.16	1	307	6	310	9.0e-117	413	COG0078	Ornithine carbamoyltransferase	310
647807207	314	23.97	6	308	3	294	2.0e-10	59.9	COG1893	Ketopantoate reductase	307
647807209	155	25.95	21	143	8	138	1.0e-07	49.2	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
647807210	829	36.97	3	829	48	845	0.0e+00	596	COG1643	HrpA-like RNA helicase	845
647807212	342	46.01	9	333	1	323	3.0e-85	308	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
647807213	96	65.75	1	73	1	73	2.0e-22	97.7	COG0227	Ribosomal protein L28	77
647807215	166	45.86	1	155	1	151	2.0e-26	112	COG2847	Copper(I)-binding protein	151
647807216	233	46.61	1	228	12	246	4.0e-67	247	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
647807217	145	40.82	1	144	2	138	5.0e-29	120	COG0394	Protein-tyrosine-phosphatase	139
647807218	321	25.45	7	280	2	273	3.0e-21	95.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
647807220	599	66	1	599	3	602	0.0e+00	1024	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
647807221	472	36.17	3	461	1	443	8.0e-106	377	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
647807222	391	47.54	1	389	2	403	2.0e-126	445	COG2081	Predicted flavoprotein YhiN	408
647807224	389	32.08	16	375	5	373	2.0e-59	223	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
647807225	365	35.91	4	362	1	357	6.0e-67	248	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
647807226	469	50	6	468	2	458	0.0e+00	557	COG0773	UDP-N-acetylmuramate-alanine ligase	459
647807229	308	42.28	10	303	2	287	4.0e-79	288	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
647807230	308	42.72	12	305	4	317	2.0e-75	276	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
647807231	299	31.55	83	286	58	262	1.0e-17	83.9	COG1589	Cell division septal protein FtsQ	269
647807232	444	33.72	18	444	2	418	4.0e-92	332	COG0849	Cell division ATPase FtsA	418
647807233	564	57.83	10	322	7	318	5.0e-108	385	COG0206	Cell division GTPase FtsZ	338
647807234	315	45.02	3	291	1	289	4.0e-85	308	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
647807235	283	37.15	9	261	1	253	1.0e-57	216	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
647807236	549	43.06	1	547	1	553	0.0e+00	502	COG0497	DNA repair ATPase RecN	557
647807237	564	31.04	39	458	18	434	1.0e-52	200	COG0038	H+/Cl- antiporter ClcA	443
647807238	230	25.63	3	230	9	244	4.0e-15	75.3	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
647807239	192	22.82	5	191	2	206	2.0e-11	62.3	COG0778	Nitroreductase	207
647807241	92	35.14	19	89	12	85	5.0e-10	56.1	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
647807246	502	53.97	16	502	1	481	0.0e+00	684	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
647807247	781	57.2	6	781	9	780	0.0e+00	938	COG2183	Transcriptional accessory protein Tex/SPT6	780
647807250	854	33.68	4	843	3	855	0.0e+00	553	COG0308	Aminopeptidase N	859
647807252	477	52.27	1	473	1	460	0.0e+00	547	COG1282	NAD/NADP transhydrogenase beta subunit	463
647807253	524	52.85	2	370	1	356	3.0e-111	396	COG3288	NAD/NADP transhydrogenase alpha subunit	356
647807254	258	39.36	1	247	2	243	5.0e-56	211	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
647807255	709	45.13	242	708	105	544	0.0e+00	471	COG2225	Malate synthase	545
647807256	426	36.64	3	424	7	417	4.0e-72	265	COG4949	Uncharacterized membrane-anchored protein	424
647807257	330	38.66	20	330	4	289	1.0e-63	236	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
647807258	335	39.4	1	334	1	315	4.0e-77	281	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
647807259	565	23.13	1	562	14	553	3.0e-61	229	COG0747	ABC-type transport system, periplasmic component	556
647807261	645	52.96	44	600	4	539	0.0e+00	675	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
647807262	388	27.75	1	388	9	408	8.0e-56	211	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647807263	388	51.3	8	383	8	387	6.0e-116	410	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
647807264	387	49.48	8	382	8	387	8.0e-120	423	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
647807268	433	39.71	15	430	4	419	3.0e-102	365	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
647807269	335	45.21	4	335	1	322	6.0e-101	360	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
647807271	225	23.98	6	225	13	212	2.0e-10	59.2	COG4912	3-methyladenine DNA glycosylase AlkD	222
647807272	602	52.48	1	602	1	597	0.0e+00	743	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
647807273	449	52.95	1	435	1	456	0.0e+00	557	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
647807274	225	35	1	217	4	219	2.0e-32	132	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
647807276	401	28.27	11	388	9	366	4.0e-51	195	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
647807279	387	44.82	6	382	1	386	1.0e-93	336	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647807281	200	41.23	5	200	3	213	9.0e-40	156	COG3047	Outer membrane protein W	213
647807282	508	34.48	16	505	2	522	2.0e-110	393	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
647807283	534	45.9	11	534	1	526	0.0e+00	632	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
647807284	645	55.96	1	643	1	645	0.0e+00	756	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
647807286	261	36.29	1	258	3	257	6.0e-42	164	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647807287	121	53.72	1	121	1	121	5.0e-32	129	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
647807288	177	69.48	21	174	12	165	6.0e-76	276	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
647807289	201	54.25	26	177	27	176	2.0e-45	175	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
647807290	405	59.18	15	405	9	398	0.0e+00	608	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
647807292	410	43.83	12	173	2	160	3.0e-50	192	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
647807294	432	58.96	1	422	5	424	0.0e+00	649	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
647807297	672	45.81	6	664	3	684	0.0e+00	632	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
647807299	345	48.36	2	333	1	331	7.0e-93	334	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
647807300	164	46.91	8	164	5	161	6.0e-46	176	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
647807302	198	47.9	1	167	5	166	8.0e-26	110	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
647807303	101	66.34	1	101	1	100	5.0e-23	99.4	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
647807304	702	48.49	4	495	3	474	4.0e-123	435	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
647807305	521	52.18	4	502	5	491	0.0e+00	525	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
647807306	478	43.67	2	459	2	456	2.0e-89	323	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
647807307	249	34.44	13	249	1	235	7.0e-43	167	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
647807308	260	43.48	1	253	1	251	9.0e-64	236	COG1521	Pantothenate kinase type III	251
647807309	555	37.12	9	551	12	554	1.0e-122	433	COG0595	mRNA degradation ribonuclease J1/J2	555
647807310	121	38.66	1	119	7	123	4.0e-28	116	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
647807311	254	51.79	9	254	1	250	7.0e-74	270	COG0149	Triosephosphate isomerase	251
647807312	117	46.3	7	112	2	109	4.0e-33	133	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
647807313	120	50	25	119	15	110	1.0e-26	111	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
647807315	295	33.8	17	294	7	291	4.0e-34	138	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
647807316	471	30.28	167	456	1	316	3.0e-55	209	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
647807317	376	57.1	7	372	1	366	0.0e+00	519	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
647807318	366	40.05	9	364	5	362	6.0e-86	311	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
647807320	802	66.58	7	777	8	782	0.0e+00	1155	COG0466	ATP-dependent Lon protease, bacterial type	782
647807324	362	24.91	90	334	28	278	6.0e-12	65.2	COG4974	Site-specific recombinase XerD	300
647807332	276	26.74	1	276	1	281	2.0e-29	123	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647807333	153	34.65	20	118	1	101	4.0e-16	77.5	COG0789	DNA-binding transcriptional regulator, MerR family	124
647807335	428	36.49	8	351	4	335	1.0e-81	297	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
647807336	124	35.96	1	113	1	114	5.0e-17	80.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
647807337	350	25	9	332	2	332	1.0e-31	130	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
647807338	432	33.56	10	432	11	445	1.0e-67	250	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
647807339	166	34.19	1	154	10	164	4.0e-23	100	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
647807342	525	35.97	14	520	8	527	2.0e-102	366	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647807343	402	32.48	1	385	1	384	7.0e-62	231	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647807344	250	39.79	6	191	3	190	7.0e-37	147	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647807345	224	24.31	24	204	17	192	4.0e-09	55.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647807346	408	43.22	16	401	5	390	9.0e-80	290	COG0183	Acetyl-CoA acetyltransferase	392
647807347	335	44.07	9	332	1	325	9.0e-74	270	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647807349	159	43.07	20	153	7	139	5.0e-31	127	COG1720	tRNA (Thr-GGU) A37 N-methylase	156
647807350	260	30.35	6	258	15	258	9.0e-33	133	COG0725	ABC-type molybdate transport system, periplasmic component	258
647807351	351	30.61	12	296	30	309	8.0e-32	131	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
647807352	340	44.41	16	340	5	334	6.0e-56	211	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
647807353	273	41.63	1	256	2	255	1.0e-75	276	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
647807354	69	60.87	1	69	1	69	7.0e-13	65.7	COG3585	Molybdopterin-binding protein	69
647807356	113	32.67	1	99	8	108	4.0e-09	53.3	COG0640	DNA-binding transcriptional regulator, ArsR family	110
647807357	155	28.57	1	153	2	149	3.0e-23	101	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
647807358	214	27.84	27	204	14	207	4.0e-19	88.3	COG0625	Glutathione S-transferase	211
647807360	713	32.77	266	652	1	408	2.0e-49	191	COG0840	Methyl-accepting chemotaxis protein	408
647807364	207	39.78	28	207	20	200	6.0e-41	160	COG4430	Uncharacterized conserved protein YdeI, YjbR/CyaY-like superfamily, DUF1801 family	200
647807365	555	32.56	1	555	1	534	4.0e-102	365	COG1574	Predicted amidohydrolase YtcJ	535
647807366	341	34.2	4	341	14	361	7.0e-68	251	COG0687	Spermidine/putrescine-binding periplasmic protein	363
647807367	266	38.58	1	266	1	263	3.0e-56	211	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
647807368	311	42.91	16	311	1	286	2.0e-68	252	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
647807369	360	52.21	1	360	5	352	2.0e-117	415	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
647807372	919	40.56	565	862	86	408	7.0e-42	166	COG0840	Methyl-accepting chemotaxis protein	408
647807373	310	23.51	15	309	5	280	8.0e-22	97.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647807374	239	31.9	1	232	4	226	2.0e-31	128	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
647807375	258	30.74	4	253	10	278	1.0e-33	136	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
647807376	242	32.07	9	241	3	236	3.0e-39	155	COG2188	DNA-binding transcriptional regulator, GntR family	236
647807377	315	33.44	4	315	8	319	5.0e-52	198	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
647807379	498	43.78	1	498	4	499	5.0e-118	418	COG3333	TctA family transporter	504
647807382	295	25.94	6	291	1	292	3.0e-30	125	COG0583	DNA-binding transcriptional regulator, LysR family	297
647807383	536	43.01	1	536	5	537	2.0e-111	396	COG2303	Choline dehydrogenase or related flavoprotein	542
647807384	391	30.27	21	388	15	372	6.0e-51	195	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
647807385	494	43.04	22	492	2	467	6.0e-129	454	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647807387	677	46	98	658	1	563	0.0e+00	648	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
647807393	334	34.46	14	325	2	314	4.0e-50	192	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647807394	334	47.65	5	321	1	319	3.0e-123	434	COG1087	UDP-glucose 4-epimerase	329
647807395	615	21.19	50	452	12	422	7.0e-38	152	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
647807396	303	38.81	41	302	84	351	2.0e-61	229	COG4124	Beta-mannanase	355
647807400	224	37.43	34	212	29	205	3.0e-25	108	COG0684	Regulator of RNase E activity RraA	210
647807402	252	36.9	1	252	5	255	5.0e-41	161	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
647807403	301	23.55	11	299	4	282	8.0e-17	81.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647807404	276	43.28	1	263	2	259	2.0e-45	176	COG0388	Predicted amidohydrolase	274
647807406	363	22.73	58	360	1	295	8.0e-21	95.2	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
647807407	577	29.14	18	572	4	533	2.0e-54	207	COG1178	ABC-type Fe3+ transport system, permease component	540
647807408	357	45.96	1	353	3	350	4.0e-100	358	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
647807409	303	29.67	3	297	1	296	9.0e-31	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
647807410	434	23.34	1	429	7	433	6.0e-44	172	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
647807411	293	38.36	3	292	2	292	2.0e-53	202	COG1175	ABC-type sugar transport system, permease component	295
647807412	283	32.39	1	281	3	278	3.0e-49	188	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
647807413	351	56.1	1	344	1	338	9.0e-130	456	COG3839	ABC-type sugar transport system, ATPase component	338
647807414	314	30.74	17	299	6	257	8.0e-32	131	COG0584	Glycerophosphoryl diester phosphodiesterase	257
647807415	303	30.26	36	301	1	256	9.0e-32	131	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
647807416	548	36.26	2	536	4	533	1.0e-93	337	COG1283	Na+/phosphate symporter	533
647807417	191	31.22	5	183	3	186	3.0e-23	101	COG0406	Broad specificity phosphatase PhoE	208
647807419	302	30.95	5	296	2	290	5.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
647807420	306	25.66	7	304	24	298	8.0e-25	107	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
647807421	322	28.9	13	309	31	298	2.0e-27	116	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
647807422	342	21.3	7	342	1	312	2.0e-27	116	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
647807424	322	25.99	1	320	4	322	2.0e-26	113	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
647807427	263	39.83	13	244	13	247	7.0e-43	167	COG1484	DNA replication protein DnaC	254
647807428	509	27.94	5	272	7	257	5.0e-19	89.4	COG4584	Transposase	278
647807430	269	57.84	1	267	1	268	4.0e-106	377	COG3718	5-deoxy-D-glucuronate isomerase	270
647807432	142	45.87	8	114	20	128	2.0e-20	92	COG3794	Plastocyanin	128
647807433	399	45.62	7	391	10	395	1.0e-68	254	COG3213	Uncharacterized protein involved in response to NO	396
647807434	226	28	6	224	3	215	3.0e-22	98.9	COG4094	Uncharacterized membrane protein	219
647807437	624	36.79	4	620	2	635	1.0e-100	360	COG4548	Nitric oxide reductase activation protein	637
647807438	266	26.53	19	245	31	271	6.0e-27	114	COG0714	MoxR-like ATPase	329
647807442	231	28.64	8	220	1	213	4.0e-31	128	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
647807444	462	33.57	29	455	7	416	4.0e-98	351	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
647807445	288	26.35	14	266	26	312	9.0e-21	94.5	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
647807446	382	21.98	45	375	77	428	3.0e-23	103	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
647807447	233	45.5	1	220	3	222	1.0e-71	262	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
647807448	117	39.37	1	117	2	126	2.0e-27	114	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
647807449	235	28.33	1	231	2	212	1.0e-46	179	COG0602	Organic radical activating enzyme	212
647807450	154	42.28	1	147	1	149	8.0e-47	179	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
647807451	241	53.51	1	113	1	114	4.0e-34	138	COG5507	Uncharacterized  conserved protein YbaA, DUF1428 family	117
647807452	217	37.63	14	101	9	101	4.0e-17	81.6	COG1733	DNA-binding transcriptional regulator, HxlR family	120
647807457	131	46.83	1	126	3	128	3.0e-35	140	COG1607	Acyl-CoA hydrolase	157
647807459	411	44.22	5	399	1	388	3.0e-116	412	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
647807460	405	18.51	30	327	4	278	3.0e-14	73.2	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
647807461	377	56.51	12	372	1	361	0.0e+00	502	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
647807462	254	28.4	7	250	1	243	5.0e-28	118	COG1651	Protein-disulfide isomerase	244
647807463	442	29.12	22	439	62	478	2.0e-55	209	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
647807464	389	34.02	15	389	4	393	2.0e-80	293	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
647807465	416	30.8	141	403	3	227	1.0e-39	157	COG0860	N-acetylmuramoyl-L-alanine amidase	231
647807468	835	43.65	1	782	1	765	0.0e+00	787	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
647807469	374	60.25	126	362	1	239	9.0e-90	324	COG1186	Protein chain release factor B	239
647807470	209	33.17	6	206	5	208	2.0e-16	79.2	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
647807471	459	36.6	1	456	3	467	4.0e-101	361	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
647807472	268	34.13	18	263	30	281	3.0e-33	135	COG5473	Uncharacterized membrane protein	290
647807476	186	54.72	28	186	4	160	4.0e-46	177	COG0440	Acetolactate synthase, small subunit	163
647807477	583	50.62	4	564	1	549	0.0e+00	642	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
647807478	214	43.33	6	209	2	211	1.0e-52	199	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
647807479	474	47.23	12	459	5	448	9.0e-126	444	COG4564	Signal transduction histidine kinase	459
647807480	361	38.94	1	352	1	357	3.0e-85	308	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
647807483	127	20.44	4	125	3	138	3.0e-06	44	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
647807484	274	49.8	1	246	1	251	1.0e-78	286	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
647807488	938	35	30	879	42	932	0.0e+00	625	COG1391	Glutamine synthetase adenylyltransferase	963
647807491	405	37.22	16	405	2	393	1.0e-81	297	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
647807493	328	25.83	8	324	2	331	3.0e-41	162	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
647807497	394	63.8	1	394	1	392	0.0e+00	534	COG3825	Uncharacterized conserved protein,  contains von Willebrand factor type A (vWA) domain	393
647807500	279	23.21	3	279	20	298	3.0e-36	145	COG0714	MoxR-like ATPase	329
647807501	158	54.17	38	157	1	120	4.0e-25	107	COG1734	RNA polymerase-binding transcription factor DksA	120
647807502	389	30.38	4	363	1	364	1.0e-43	170	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647807503	333	45.45	1	259	1	252	2.0e-78	285	COG0708	Exonuclease III	261
647807508	107	47.71	1	106	1	109	8.0e-30	121	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
647807509	380	42.46	4	376	11	408	3.0e-98	351	COG0232	dGTP triphosphohydrolase	412
647807510	580	37.54	1	580	1	577	0.0e+00	512	COG0018	Arginyl-tRNA synthetase	577
647807512	364	35.29	4	337	6	313	8.0e-52	197	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
647807513	265	33.74	22	265	2	243	1.0e-34	140	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
647807514	227	45.71	26	196	6	179	2.0e-44	172	COG1386	Chromosome segregation and condensation protein ScpB	184
647807516	398	30.99	1	380	4	387	3.0e-32	133	COG2814	Predicted arabinose efflux permease, MFS family	394
647807517	174	37.33	13	159	2	151	6.0e-25	107	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647807518	359	26.82	179	357	20	182	3.0e-27	116	COG0717	Deoxycytidine triphosphate deaminase	183
647807520	701	32.63	10	104	2	95	5.0e-15	76.7	COG0789	DNA-binding transcriptional regulator, MerR family	124
647807521	109	41.76	14	104	1	91	7.0e-26	108	COG0776	Bacterial nucleoid DNA-binding protein	94
647807522	323	54.43	2	323	1	322	1.0e-109	389	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
647807523	375	46.41	17	349	4	333	2.0e-97	349	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
647807524	68	50	1	56	1	56	1.0e-16	78.4	COG0333	Ribosomal protein L32	57
647807526	155	28.67	6	144	5	146	1.0e-12	66.2	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
647807527	258	26.04	12	258	25	288	3.0e-18	85.8	COG3176	Putative hemolysin	292
647807528	601	36.41	5	502	2	528	1.0e-126	447	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
647807529	251	34.22	1	249	1	251	3.0e-30	125	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647807531	415	45.85	6	413	2	400	8.0e-120	423	COG0162	Tyrosyl-tRNA synthetase	401
647807532	375	36.6	10	367	4	371	3.0e-69	255	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
647807533	150	49.29	6	142	5	141	1.0e-34	138	COG3542	Predicted sugar epimerase, cupin superfamily	162
647807534	495	44.79	25	495	5	488	0.0e+00	530	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
647807535	442	45.19	1	442	28	469	3.0e-114	405	COG0513	Superfamily II DNA and RNA helicase	513
647807538	138	51.52	1	132	4	135	4.0e-36	143	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
647807539	335	19.24	39	323	3	292	1.0e-05	44.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
647807542	439	69.88	15	439	1	422	0.0e+00	659	COG0148	Enolase	423
647807545	313	54.98	3	313	2	310	6.0e-112	397	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
647807547	387	46.79	1	383	2	388	3.0e-115	408	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
647807548	321	33.89	28	314	3	301	3.0e-56	212	COG0010	Arginase family enzyme	305
647807549	315	43.93	15	312	2	304	5.0e-65	241	COG0010	Arginase family enzyme	305
647807551	444	61.88	93	444	1	362	0.0e+00	511	COG0216	Protein chain release factor A	363
647807552	278	43.17	3	276	1	275	2.0e-55	209	COG2890	Methylase of polypeptide chain release factors	280
647807554	280	47.91	18	279	1	256	2.0e-75	275	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
647807555	326	51.06	3	325	1	330	1.0e-96	346	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
647807556	425	16.85	27	297	7	281	3.0e-08	53.2	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
647807557	733	21.63	2	726	7	772	3.0e-65	243	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
647807558	368	26.68	1	368	2	364	2.0e-36	147	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
647807559	379	25.62	1	357	1	358	6.0e-30	125	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
647807560	490	45.81	11	488	2	485	7.0e-128	450	COG0260	Leucyl aminopeptidase	485
647807561	154	34	1	148	1	144	2.0e-22	98.8	COG2927	DNA polymerase III, chi subunit	144
647807562	193	38.42	1	191	12	213	2.0e-38	152	COG3577	Predicted aspartyl protease	215
647807563	207	46.31	1	203	1	199	8.0e-35	140	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
647807564	620	43.07	1	514	3	525	0.0e+00	500	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
647807565	529	31.93	1	358	30	407	2.0e-40	160	COG3673	Uncharacterized protein, PA2063/DUF2235 family	423
647807567	402	22.77	8	385	12	386	1.0e-19	91.4	COG2814	Predicted arabinose efflux permease, MFS family	394
647807568	140	58.96	2	135	1	134	1.0e-53	202	COG0105	Nucleoside diphosphate kinase	135
647807570	488	26.79	49	317	1	275	3.0e-23	103	COG0836	Mannose-1-phosphate guanylyltransferase	333
647807577	317	28.35	1	316	1	245	1.0e-28	120	COG4422	Bacteriophage protein gp37	250
647807587	240	26.43	1	215	8	223	9.0e-22	97.2	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
647807606	473	28.69	8	466	1	435	3.0e-60	226	COG0305	Replicative DNA helicase	435
647807632	184	26.15	1	183	43	228	5.0e-10	57.7	COG0860	N-acetylmuramoyl-L-alanine amidase	231
647807635	214	36.06	11	213	1	208	2.0e-41	162	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
647807636	155	38.71	1	154	1	154	5.0e-33	133	COG3915	Uncharacterized protein	155
647807637	825	37.22	314	578	79	336	4.0e-37	150	COG0642	Signal transduction histidine kinase	336
647807640	273	21.03	11	262	6	227	1.0e-09	57.3	COG2801	Transposase InsO and inactivated derivatives	232
647807642	336	39.6	16	310	12	301	9.0e-73	267	COG0042	tRNA-dihydrouridine synthase	323
647807644	78	40	9	78	4	71	5.0e-09	52.7	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
647807645	157	50	16	152	1	138	5.0e-40	156	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
647807646	413	26.67	1	315	1	287	6.0e-23	101	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
647807647	414	26.65	29	404	1	387	1.0e-51	197	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647807650	110	50.59	1	83	1	84	1.0e-21	94.6	COG4311	Sarcosine oxidase delta subunit	97
647807651	1011	36.59	614	1011	2	379	5.0e-90	326	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
647807652	182	28.67	33	174	46	186	1.0e-11	63	COG4583	Sarcosine oxidase gamma subunit	189
647807654	199	50	1	198	2	197	4.0e-63	233	COG0605	Superoxide dismutase	204
647807656	150	30.28	4	145	6	137	3.0e-24	104	COG5622	Protein required for attachment to host cells	139
647807657	180	37.16	1	179	12	193	2.0e-33	135	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
647807659	602	59.96	99	594	1	497	0.0e+00	652	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
647807662	162	35.56	6	139	3	137	1.0e-25	109	COG3837	Uncharacterized conserved protein, cupin superfamily	161
647807664	611	41.93	257	553	87	408	6.0e-49	189	COG0840	Methyl-accepting chemotaxis protein	408
647807665	192	24.48	5	147	1	137	1.0e-16	79.9	COG1695	DNA-binding transcriptional regulator, PadR family	138
647807667	1270	22.66	3	1189	1	1005	0.0e+00	489	COG0841	Multidrug efflux pump subunit AcrB	1009
647807669	229	30.39	12	210	4	206	2.0e-15	76.6	COG4649	Uncharacterized protein	221
647807670	442	22.13	73	409	28	370	3.0e-21	96.8	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
647807673	492	42.19	1	474	2	444	0.0e+00	521	COG1160	Predicted GTPases	444
647807674	216	39	7	206	4	199	2.0e-27	116	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
647807675	317	22.05	1	316	19	327	1.0e-24	107	COG3239	Fatty acid desaturase	343
647807677	430	52.56	1	426	1	428	0.0e+00	519	COG0172	Seryl-tRNA synthetase	429
647807679	94	47.83	3	94	6	96	7.0e-22	95.3	COG1862	Preprotein translocase subunit YajC	97
647807680	554	45.79	51	554	18	506	3.0e-123	435	COG0342	Preprotein translocase subunit SecD	506
647807681	322	45.54	3	305	1	294	3.0e-76	278	COG0341	Preprotein translocase subunit SecF	305
647807683	117	42.28	1	116	5	127	6.0e-21	92.7	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
647807685	204	39.9	1	191	2	209	1.0e-42	166	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
647807686	218	53	1	217	4	220	5.0e-36	144	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
647807687	244	36.73	6	230	41	265	2.0e-25	109	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
647807689	178	25.78	32	155	1	126	8.0e-10	56.8	COG0526	Thiol-disulfide isomerase or thioredoxin	127
647807690	234	39.76	1	233	4	251	6.0e-40	157	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647807692	915	59.69	8	914	1	861	0.0e+00	1177	COG1048	Aconitase A	861
647807693	235	34.98	1	232	17	253	2.0e-43	169	COG5429	Uncharacterized protein	261
647807694	305	28.92	25	304	23	308	4.0e-44	171	COG1560	Lauroyl/myristoyl acyltransferase	308
647807695	367	27.08	33	366	7	337	7.0e-25	108	COG1536	Flagellar motor switch protein FliG	339
647807699	434	48.63	1	434	1	438	0.0e+00	511	COG0015	Adenylosuccinate lyase	438
647807701	423	27.34	267	403	4	134	1.0e-20	94.3	COG1765	Uncharacterized OsmC-related protein	137
647807703	299	24.59	11	294	4	307	1.0e-18	87.3	COG3021	Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily	309
647807704	447	22.94	47	438	1	377	5.0e-35	142	COG0006	Xaa-Pro aminopeptidase	384
647807711	468	46.11	1	468	1	443	0.0e+00	496	COG0174	Glutamine synthetase	443
647807712	112	75.89	1	112	1	112	4.0e-40	156	COG0347	Nitrogen regulatory protein PII	112
647807713	355	35.65	1	230	1	203	2.0e-44	173	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
647807716	927	32.84	1	927	1	852	0.0e+00	932	COG1049	Aconitase B	852
647807717	796	33.17	338	731	1	408	3.0e-52	200	COG0840	Methyl-accepting chemotaxis protein	408
647807718	1241	31.58	252	514	1	264	3.0e-55	210	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
647807721	131	28.57	1	125	5	130	4.0e-16	77.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
647807725	444	41.35	2	439	1	441	1.0e-83	304	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
647807726	313	40.45	146	313	2	179	3.0e-28	119	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
647807727	652	34.72	9	580	1	517	4.0e-107	382	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
647807728	229	43.4	1	225	4	238	5.0e-42	164	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
647807730	282	21.05	3	279	2	286	3.0e-16	79.3	COG1344	Flagellin and related hook-associated protein FlgL	360
647807731	280	21.4	3	277	2	286	5.0e-17	82	COG1344	Flagellin and related hook-associated protein FlgL	360
647807732	283	23.66	3	273	2	280	2.0e-17	83.6	COG1344	Flagellin and related hook-associated protein FlgL	360
647807733	205	44.22	1	147	1	147	3.0e-40	158	COG0359	Ribosomal protein L9	148
647807734	75	71.64	4	70	9	75	8.0e-20	88.4	COG0238	Ribosomal protein S18	75
647807735	117	43.64	4	113	3	112	1.0e-24	104	COG0360	Ribosomal protein S6	112
647807737	191	45.31	1	191	1	192	8.0e-41	160	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
647807738	257	31.73	1	255	9	278	7.0e-41	160	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
647807739	260	17.98	1	245	3	262	1.0e-05	43.9	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
647807740	410	32.81	5	196	3	181	1.0e-28	121	COG3038	Cytochrome b561	181
647807741	311	54.55	1	308	2	307	3.0e-88	318	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
647807742	245	48.82	2	243	1	251	5.0e-48	184	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647807744	77	60	1	75	3	77	4.0e-12	63	COG0236	Acyl carrier protein	80
647807745	247	39.58	1	239	2	241	4.0e-54	204	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
647807746	422	57.45	1	420	2	411	0.0e+00	470	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
647807747	384	34.29	1	380	4	342	9.0e-82	297	COG1559	Cell division protein YceG, involved in septum cleavage	342
647807749	478	53.33	74	478	29	410	3.0e-104	372	COG5323	Large terminase phage packaging protein	410
647807750	401	41.78	20	395	12	384	8.0e-77	281	COG4695	Phage portal protein BeeE	398
647807752	190	27.38	27	179	26	189	4.0e-21	94.7	COG3740	Phage head maturation protease	194
647807753	398	34.05	1	396	3	419	1.0e-73	270	COG4653	Predicted phage phi-C31 gp36 major capsid-like protein	422
647807755	112	29.36	1	109	3	106	6.0e-07	46.1	COG5614	Bacteriophage head-tail adaptor	109
647807757	137	50	1	136	1	136	5.0e-40	156	COG5437	Predicted secreted protein	138
647807761	210	42.7	26	210	1	184	4.0e-49	187	COG5448	Uncharacterized protein	184
647807765	68	54.41	1	68	1	67	2.0e-18	84	COG1278	Cold shock protein, CspA family	67
647807767	268	51.89	84	268	5	189	1.0e-63	236	COG1045	Serine acetyltransferase	194
647807768	441	43.44	1	440	1	402	2.0e-96	346	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
647807769	459	53.73	138	458	3	323	0.0e+00	463	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
647807770	337	50.45	3	334	15	348	7.0e-112	397	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
647807772	99	28.24	13	97	26	107	4.0e-06	43	COG2919	Cell division protein FtsB	117
647807773	122	44.34	16	121	1	106	3.0e-27	113	COG4551	Predicted protein tyrosine phosphatase	109
647807774	590	39.45	311	574	118	406	4.0e-30	126	COG0840	Methyl-accepting chemotaxis protein	408
647807775	396	51.26	4	395	5	391	0.0e+00	478	COG0126	3-phosphoglycerate kinase	395
647807776	168	42.77	10	166	1	158	7.0e-41	160	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
647807777	182	41.03	31	182	9	158	9.0e-40	156	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
647807779	176	29.17	37	153	7	126	2.0e-17	81.9	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
647807780	443	33.33	181	440	10	268	1.0e-36	147	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
647807781	280	45.56	7	275	4	267	7.0e-70	257	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
647807782	153	58.17	1	153	3	155	5.0e-57	213	COG1225	Peroxiredoxin	157
647807784	369	52.97	21	369	1	344	1.0e-128	453	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
647807785	424	19.66	37	378	44	394	2.0e-08	53.7	COG2814	Predicted arabinose efflux permease, MFS family	394
647807786	192	44.44	2	181	7	182	4.0e-45	174	COG3803	Uncharacterized conserved protein, DUF924 family	182
647807788	464	45.9	6	453	5	453	0.0e+00	468	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
647807789	400	21.78	52	394	48	391	3.0e-08	53.3	COG2814	Predicted arabinose efflux permease, MFS family	394
647807790	972	66.77	14	963	4	935	0.0e+00	1545	COG0178	Excinuclease UvrABC ATPase subunit	935
647807794	290	45.58	1	285	1	286	7.0e-67	247	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
647807795	346	27.35	1	244	4	242	4.0e-32	132	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647807796	381	43.3	1	377	1	387	4.0e-90	325	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647807797	616	32.85	63	604	68	620	1.0e-98	354	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
647807799	481	36.53	6	465	3	469	1.0e-105	377	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647807800	298	22.59	3	293	1	297	3.0e-24	106	COG0583	DNA-binding transcriptional regulator, LysR family	297
647807802	165	50	1	162	2	158	1.0e-52	199	COG0669	Phosphopantetheine adenylyltransferase	159
647807804	333	54.82	2	330	1	331	4.0e-116	411	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
647807805	319	48.66	2	299	4	292	1.0e-79	290	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
647807806	673	50.37	17	672	10	662	0.0e+00	827	COG0021	Transketolase	663
647807808	170	25.56	1	90	1	90	1.0e-06	46.1	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
647807809	120	55.24	1	104	1	105	5.0e-39	152	COG0278	Glutaredoxin-related protein	105
647807811	78	37.5	1	78	1	85	1.0e-12	65	COG0271	Stress-induced morphogen (activity unknown)	90
647807812	721	50.55	6	709	14	733	0.0e+00	847	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
647807813	301	32.01	1	294	1	297	1.0e-37	150	COG0583	DNA-binding transcriptional regulator, LysR family	297
647807814	1139	30.23	16	693	1	634	0.0e+00	524	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
647807815	292	23.04	30	257	30	254	9.0e-18	84.2	COG3176	Putative hemolysin	292
647807816	269	31.02	1	269	6	264	2.0e-51	195	COG0796	Glutamate racemase	269
647807818	342	44	1	342	1	349	1.0e-96	346	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
647807819	147	45.77	5	144	4	145	4.0e-34	137	COG2332	Cytochrome c-type biogenesis protein CcmE	153
647807822	654	50.62	1	645	1	648	0.0e+00	599	COG1138	Cytochrome c biogenesis factor	648
647807823	155	41.78	9	154	10	151	1.0e-34	138	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
647807825	259	39.38	1	256	2	257	4.0e-49	188	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647807827	431	53.58	28	431	1	390	0.0e+00	495	COG0372	Citrate synthase	390
647807828	466	37.47	1	464	6	469	9.0e-116	410	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
647807829	673	24.41	18	484	10	447	1.0e-31	131	COG0658	Predicted membrane metal-binding protein	453
647807830	232	39.22	1	232	3	200	2.0e-51	195	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
647807831	390	44.7	1	390	6	401	9.0e-95	340	COG0303	Molybdopterin biosynthesis enzyme	404
647807833	156	61.54	1	156	2	156	5.0e-55	207	COG0315	Molybdenum cofactor biosynthesis enzyme	157
647807834	269	54.09	6	262	1	254	6.0e-83	300	COG0134	Indole-3-glycerol phosphate synthase	254
647807835	234	47.14	22	224	15	223	2.0e-67	249	COG0692	Uracil DNA glycosylase	223
647807836	340	50.44	2	338	1	338	4.0e-102	364	COG0547	Anthranilate phosphoribosyltransferase	338
647807837	193	59.04	1	187	3	189	1.0e-75	275	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
647807839	499	25.62	303	487	44	241	6.0e-08	52.6	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
647807840	503	46.67	21	498	1	461	0.0e+00	485	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
647807842	391	28.49	32	389	30	388	8.0e-63	234	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
647807843	176	34.64	16	165	6	149	2.0e-18	85.4	COG2236	Hypoxanthine phosphoribosyltransferase	192
647807844	268	68.48	5	261	3	259	8.0e-117	413	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
647807845	201	49.25	4	201	18	214	2.0e-63	235	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
647807846	180	29.23	12	76	3	67	2.0e-10	59	COG1278	Cold shock protein, CspA family	67
647807847	156	42.24	36	151	12	126	3.0e-30	124	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
647807850	1055	19.21	6	631	91	583	2.0e-57	217	COG0209	Ribonucleotide reductase alpha subunit	696
647807853	457	44.73	3	441	1	460	0.0e+00	536	COG0215	Cysteinyl-tRNA synthetase	464
647807854	542	34.19	3	431	1	409	3.0e-95	343	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
647807855	258	23.93	1	253	4	282	4.0e-13	68.5	COG1562	Phytoene/squalene synthetase	288
647807856	405	19.4	1	393	1	388	2.0e-06	47.5	COG2814	Predicted arabinose efflux permease, MFS family	394
647807857	210	40.09	20	210	72	283	6.0e-38	150	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
647807858	217	27.96	5	215	9	206	2.0e-27	116	COG0400	Predicted esterase	207
647807859	227	36.79	3	187	64	238	2.0e-43	168	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
647807860	194	39.46	33	176	1	146	1.0e-23	103	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
647807861	348	40.3	10	330	4	330	8.0e-84	304	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
647807862	309	36.54	5	302	23	305	2.0e-55	209	COG0010	Arginase family enzyme	305
647807863	145	31.97	1	144	6	152	6.0e-18	83.6	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647807864	154	30.52	2	150	10	163	3.0e-12	64.7	COG1495	Disulfide bond formation protein DsbB	170
647807865	192	35.4	1	161	1	158	2.0e-21	95.7	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
647807870	323	30.7	4	307	80	408	2.0e-24	106	COG0840	Methyl-accepting chemotaxis protein	408
647807871	349	51.88	1	344	1	338	7.0e-122	430	COG3839	ABC-type sugar transport system, ATPase component	338
647807872	302	31.6	16	300	2	278	8.0e-48	184	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
647807873	293	36.43	1	289	1	290	1.0e-47	183	COG1175	ABC-type sugar transport system, permease component	295
647807874	435	24.31	6	430	13	433	2.0e-41	164	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
647807875	329	38.68	7	324	5	319	2.0e-76	279	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
647807876	354	51.49	20	354	19	354	4.0e-99	355	COG5621	Predicted secreted hydrolase	354
647807878	220	41.82	2	215	1	220	4.0e-63	234	COG1136	ABC-type lipoprotein export system, ATPase component	226
647807880	287	28.57	11	287	17	293	1.0e-32	133	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
647807882	238	45.93	31	238	3	203	1.0e-58	219	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
647807886	321	19.57	39	305	17	283	4.0e-23	102	COG0685	5,10-methylenetetrahydrofolate reductase	291
647807892	202	55.34	1	102	1	102	9.0e-30	123	COG0261	Ribosomal protein L21	103
647807893	89	63.22	1	87	1	87	2.0e-29	120	COG0211	Ribosomal protein L27	87
647807894	178	27.17	12	176	5	177	3.0e-17	81.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
647807895	348	58.33	1	342	1	348	0.0e+00	472	COG0536	GTPase involved in cell partioning and DNA repair	369
647807896	368	52.16	3	368	2	368	1.0e-114	406	COG0263	Glutamate 5-kinase	369
647807897	421	55.66	9	421	3	417	0.0e+00	544	COG0014	Gamma-glutamyl phosphate reductase	417
647807898	198	29.9	1	197	7	209	5.0e-21	94.7	COG5385	Uncharacterized protein	214
647807900	253	34.8	4	246	34	283	8.0e-39	153	COG3176	Putative hemolysin	292
647807901	283	29.15	26	240	1	220	5.0e-20	91.9	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
647807903	256	57.14	3	254	1	252	3.0e-101	361	COG0052	Ribosomal protein S2	252
647807904	291	56	1	291	2	296	3.0e-83	301	COG0264	Translation elongation factor EF-Ts	296
647807906	149	54.79	2	147	1	146	1.0e-54	205	COG0757	3-dehydroquinate dehydratase	146
647807907	236	31.55	27	225	27	231	3.0e-18	85.5	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647807910	143	45.65	6	143	47	184	1.0e-34	138	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
647807911	540	34.23	23	539	58	557	1.0e-92	333	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
647807912	357	38.14	2	355	4	338	8.0e-69	254	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
647807914	402	43.1	1	402	2	411	1.0e-107	383	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
647807915	214	28.03	54	208	24	176	5.0e-17	81.2	COG5342	Invasion protein IalB, involved in pathogenesis	181
647807917	514	26.87	25	508	8	519	1.0e-33	138	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
647807918	559	30.14	331	548	1	170	3.0e-35	143	COG0516	IMP dehydrogenase/GMP reductase	170
647807919	382	45.83	1	382	4	383	3.0e-110	392	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
647807920	714	39.47	37	713	1	613	0.0e+00	545	COG3894	Uncharacterized 2Fe-2 and 4Fe-4S clusters-containing protein, contains DUF4445 domain	614
647807921	393	30.23	113	393	46	355	1.0e-53	204	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
647807922	769	31.2	370	630	89	336	2.0e-36	147	COG0642	Signal transduction histidine kinase	336
647807924	357	64.54	15	293	6	279	3.0e-87	315	COG0468	RecA/RadA recombinase	279
647807926	903	51.4	20	903	5	878	0.0e+00	1109	COG0013	Alanyl-tRNA synthetase	879
647807927	95	51.61	1	92	2	94	1.0e-22	97.6	COG5470	Uncharacterized conserved protein, DUF1330 family	96
647807928	258	30.65	1	241	1	238	7.0e-47	180	COG0121	Predicted glutamine amidotransferase	252
647807929	606	60.76	1	604	3	602	0.0e+00	933	COG1217	Predicted membrane GTPase involved in stress response	603
647807930	109	45.19	1	104	2	105	1.0e-17	81.7	COG2076	Multidrug transporter EmrE and related cation transporters	106
647807931	388	31.91	199	335	6	142	8.0e-14	71.9	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
647807933	173	56.02	2	167	49	207	5.0e-54	204	COG2945	Alpha/beta superfamily hydrolase	210
647807937	112	30.23	20	100	19	98	3.0e-06	43.8	COG5489	Uncharacterized conserved protein, DUF736 family	107
647807943	505	38.7	4	505	1	488	5.0e-106	378	COG0286	Type I restriction-modification system, DNA methylase subunit	489
647807944	400	20.99	47	392	34	391	2.0e-21	97.4	COG0732	Restriction endonuclease S subunit	391
647807946	894	28.46	29	785	19	707	4.0e-107	382	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
647807948	238	25.65	6	235	3	215	2.0e-29	122	COG1451	Predicted metal-dependent hydrolase	223
647807952	198	35.96	18	193	1	176	2.0e-32	132	COG1386	Chromosome segregation and condensation protein ScpB	184
647807954	341	28.1	36	324	23	281	1.0e-16	80.6	COG4974	Site-specific recombinase XerD	300
647807957	332	26.89	53	285	1	230	1.0e-17	84.2	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
647807959	403	30.66	121	392	3	258	2.0e-47	183	COG1192	Cellulose biosynthesis protein BcsQ	259
647807960	112	30.23	20	100	19	98	3.0e-06	44.1	COG5489	Uncharacterized conserved protein, DUF736 family	107
647807970	99	33.33	1	96	1	96	7.0e-16	75.5	COG3668	Plasmid stabilization system protein ParE	98
647807971	83	36.05	1	82	2	87	5.0e-07	45.8	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
647807978	483	21.49	80	456	23	281	1.0e-18	88.3	COG4974	Site-specific recombinase XerD	300
647807980	369	28.78	27	353	9	285	2.0e-33	136	COG4974	Site-specific recombinase XerD	300
647807981	695	27.41	244	559	3	295	2.0e-18	87.6	COG4974	Site-specific recombinase XerD	300
647807986	723	26.78	30	208	4	174	7.0e-11	63	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
647807987	505	43.81	112	498	4	378	2.0e-116	412	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
647807988	233	37	4	228	13	238	5.0e-38	151	COG2186	DNA-binding transcriptional regulator, FadR family	241
647807989	230	34.95	1	199	1	200	1.0e-35	143	COG0625	Glutathione S-transferase	211
647807990	549	26.97	98	539	25	456	9.0e-52	198	COG0277	FAD/FMN-containing dehydrogenase	459
647807991	331	29.7	23	324	15	315	2.0e-43	169	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
647807993	510	39.44	1	497	1	489	2.0e-105	376	COG3333	TctA family transporter	504
647807994	268	34.71	23	262	1	242	2.0e-42	165	COG1414	DNA-binding transcriptional regulator, IclR family	246
647807995	482	48.4	14	480	2	467	0.0e+00	517	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647807996	465	39.75	7	462	3	466	9.0e-103	367	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647808003	142	20.66	17	136	1	116	6.0e-10	56.8	COG2963	Transposase and inactivated derivatives	116
647808012	391	45.88	5	382	6	386	5.0e-86	311	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647808013	418	38.89	20	414	6	395	2.0e-91	329	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
647808015	627	42.93	13	620	27	636	7.0e-122	431	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
647808016	349	27.89	16	348	11	321	1.0e-38	153	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
647808019	245	33.88	1	239	6	249	4.0e-41	161	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647808021	252	49.43	1	252	1	259	4.0e-68	251	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
647808022	309	54.92	2	309	1	310	3.0e-85	308	COG2025	Electron transfer flavoprotein, alpha subunit	313
647808028	93	39.74	16	93	24	100	4.0e-06	42.9	COG3838	Type IV secretory pathway, VirB2 components (pilins)	108
647808031	797	30.54	30	797	13	787	6.0e-115	408	COG3451	Type IV secretory pathway, VirB4 component	796
647808038	226	35.35	15	226	27	236	4.0e-31	128	COG3736	Type IV secretory pathway, component VirB8	239
647808039	240	33.06	4	230	7	236	5.0e-33	134	COG3504	Type IV secretory pathway, VirB9 components	265
647808041	372	33.09	104	371	74	351	3.0e-37	149	COG2948	Type IV secretory pathway, VirB10 components	360
647808045	481	21.99	18	308	26	258	3.0e-20	93.2	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
647808048	390	44.53	5	383	2	380	6.0e-104	371	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
647808049	608	18.33	25	433	18	402	4.0e-17	83.4	COG1479	Uncharacterized conserved protein, contains ParB-like and HNH nuclease domains	409
647808061	1045	30.2	86	578	111	591	4.0e-75	276	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
