gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
2904474042	309	98.7	1	306	1	303	0.0e+00	505.1	COG1897	Homoserine trans-succinylase	307
2904474043	532	97.4	1	532	12	572	0.0e+00	649.5	COG2225	Malate synthase	545
2904474044	440	38.98	249	435	289	472	0.0e+00	277	COG2224	Isocitrate lyase	433
2904474044	440	55.08	1	257	3	262	0.0e+00	370.9	COG2224	Isocitrate lyase	433
2904474045	570	98.44	1	570	4	572	0.0e+00	980.2	COG4579	Isocitrate dehydrogenase kinase/phosphatase	578
2904474046	280	99.59	30	277	1	245	6.7e-85	278	COG1414	DNA-binding transcriptional regulator, IclR family	246
2904474047	1227	98.72	1	327	4	311	0.0e+00	435.7	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
2904474047	1227	99.88	328	1192	2	857	0.0e+00	1401.6	COG1410	Methionine synthase I, cobalamin-binding domain	842
2904474048	236	96.23	1	235	8	237	4.2e-61	200.8	COG2188	DNA-binding transcriptional regulator, GntR family	236
2904474049	352	98.01	54	349	4	298	1.7e-50	166.3	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2904474050	265	65.69	1	262	42	355	4.0e-38	120.8	COG1524	Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily	450
2904474051	280	98.94	1	279	1	279	7.9e-113	370.8	COG4132	ABC-type uncharacterized transport system, permease component	282
2904474052	261	94.76	1	261	9	261	3.7e-54	178.1	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2904474053	330	96.6	1	328	4	344	3.1e-116	382.2	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2904474054	218	93.4	1	218	5	202	2.4e-57	188.1	COG0560	Phosphoserine phosphatase	212
2904474055	550	99.07	1	534	5	534	0.0e+00	621.4	COG1283	Na+/phosphate symporter	533
2904474056	305	93.83	1	305	10	313	4.0e-94	309.7	COG0385	Predicted Na+-dependent transporter	319
2904474057	462	99.32	11	462	3	442	0.0e+00	436.3	COG0527	Aspartokinase	447
2904474059	548	99.34	43	538	4	453	0.0e+00	687.8	COG0166	Glucose-6-phosphate isomerase	446
2904474060	122	87.68	1	122	17	137	9.1e-53	172.2	COG3223	Phosphate starvation-inducible membrane PsiE (function unknown)	138
2904474061	179	96.05	9	173	6	175	3.0e-47	154.6	COG3161	4-hydroxybenzoate synthetase (chorismate-pyruvate lyase)	174
2904474062	292	97.93	2	288	5	288	4.3e-99	325.3	COG0382	4-hydroxybenzoate polyprenyltransferase	289
2904474063	827	99.38	1	808	1	805	0.0e+00	1265.4	COG2937	Glycerol-3-phosphate O-acyltransferase	810
2904474064	122	96.75	1	122	2	120	3.3e-47	153.6	COG0818	Diacylglycerol kinase	123
2904474065	202	99.01	1	200	1	201	2.5e-73	240.3	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2904474066	454	95.43	7	452	16	454	1.2e-96	318.1	COG0534	Na+-driven multidrug efflux pump	455
2904474067	69	94.03	1	65	4	66	8.0e-29	93.9	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2904474068	184	94.48	19	167	5	141	1.7e-44	145.6	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2904474069	335	96	4	330	9	320	3.2e-97	319.7	COG0042	tRNA-dihydrouridine synthase	323
2904474070	78	46.81	1	77	10	75	1.2e-04	16.7	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
2904474071	327	99.09	2	327	2	329	3.9e-100	329.7	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2904474072	468	99.31	22	462	2	434	0.0e+00	581.7	COG0305	Replicative DNA helicase	435
2904474073	359	99.45	1	358	2	363	0.0e+00	435	COG0787	Alanine racemase	360
2904474074	259	92.93	1	259	11	273	1.2e-31	104.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904474075	154	93.67	1	153	5	152	1.7e-28	94	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2904474076	210	66.1	18	210	15	207	7.3e-39	127.8	COG1284	Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains	289
2904474077	67	6.72	37	66	250	267	8.1e-14	9.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904474077	67	14.93	5	47	2	41	8.1e-14	39	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904474078	397	99.75	1	397	1	395	0.0e+00	565.6	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
2904474079	261	98.03	6	258	4	252	4.3e-79	259.9	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2904474080	298	98.42	3	297	2	312	2.5e-67	221.4	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2904474081	298	99.3	2	287	2	285	1.0e-97	321.1	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2904474082	292	97.71	1	292	7	305	3.1e-122	401.8	COG3684	Tagatose-1,6-bisphosphate aldolase	306
2904474083	413	99.48	1	399	1	386	0.0e+00	473.2	COG2942	Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family	388
2904474084	678	86.35	1	677	8	684	0.0e+00	605.6	COG1501	Alpha-glucosidase, glycosyl hydrolase family GH31	772
2904474085	461	97.63	6	461	2	455	0.0e+00	516.7	COG2211	Na+/melibiose symporter or related transporter	467
2904474086	471	96.77	4	466	7	456	0.0e+00	515.1	COG2211	Na+/melibiose symporter or related transporter	467
2904474087	117	98.32	1	117	1	117	1.4e-39	129.3	COG2315	Predicted DNA-binding protein with ?double-wing? structural motif, MmcQ/YjbR family	118
2904474088	306	24.71	181	236	65	107	1.6e-21	8.1	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2904474088	306	91.38	5	195	1	159	1.6e-21	62.5	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2904474089	206	93.95	4	203	2	203	3.7e-41	135.6	COG0625	Glutathione S-transferase	211
2904474090	305	98.67	2	296	2	298	5.1e-67	221	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904474091	394	96.67	78	394	9	298	1.2e-82	271.7	COG2382	Enterochelin esterase or related enzyme	299
2904474092	346	55.96	48	202	89	210	2.1e-04	14.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2904474094	951	99.68	1	942	3	940	0.0e+00	1514.7	COG0178	Excinuclease UvrABC ATPase subunit	935
2904474095	180	99.42	3	180	2	171	7.8e-60	196.5	COG0629	Single-stranded DNA-binding protein	167
2904474096	466	87.74	72	466	24	395	3.2e-35	115.6	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2904474097	284	97.01	7	284	4	295	1.1e-53	177.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904474101	385	87.02	1	357	3	344	3.5e-51	169	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2904474103	161	24.85	12	157	168	290	3.1e-06	20.4	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
2904474104	300	98.67	2	298	2	298	6.0e-72	237.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904474105	246	98.88	2	246	3	267	1.9e-73	241.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904474106	84	84.15	4	82	4	72	2.1e-08	28.7	COG2336	Antitoxin component of the MazEF toxin-antitoxin module	82
2904474107	114	94.59	2	108	2	106	4.0e-24	79.2	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
2904474108	126	75.36	67	124	4	55	2.0e-09	15.8	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2904474108	126	78.26	1	65	1	54	2.0e-09	14	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2904474109	301	94.02	1	288	10	292	1.7e-31	103.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2904474110	292	77.27	162	290	22	123	3.8e-28	91	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904474111	177	80.75	2	165	5	155	3.3e-28	93.1	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2904474112	207	94.42	2	205	1	203	2.0e-46	152.8	COG0625	Glutathione S-transferase	211
2904474113	371	76.95	1	306	1	247	1.2e-27	91.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2904474114	285	88.32	1	280	27	268	7.1e-65	213.2	COG1718	Serine/threonine-protein kinase RIO1	268
2904474115	246	86.52	1	239	33	263	9.3e-42	137.3	COG0725	ABC-type molybdate transport system, periplasmic component	258
2904474116	362	96.91	4	332	11	324	4.6e-70	230.6	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2904474117	210	98.56	2	209	2	206	8.1e-58	189.3	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2904474118	267	98.07	5	261	1	254	7.8e-65	212.8	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2904474119	520	91.53	68	517	36	424	1.8e-92	304.8	COG0840	Methyl-accepting chemotaxis protein	408
2904474120	697	69.68	134	690	179	640	4.3e-102	336.2	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2904474121	222	94.88	1	217	5	208	1.1e-43	143.9	COG0625	Glutathione S-transferase	211
2904474122	455	98.65	13	453	4	440	0.0e+00	482	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
2904474123	549	98.39	1	449	6	434	1.2e-124	410.2	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
2904474124	292	97.67	1	292	1	294	2.0e-70	232.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904474125	140	94.53	12	139	5	125	2.1e-36	118.6	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
2904474126	229	96.96	2	229	6	228	3.0e-78	256.5	COG1346	Putative effector of murein hydrolase	230
2904474127	253	99.59	12	252	1	241	8.3e-118	386	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2904474128	369	93.86	105	366	13	226	2.2e-65	214.3	COG0765	ABC-type amino acid transport system, permease component	222
2904474129	392	97.98	1	392	9	397	0.0e+00	611.5	COG4597	ABC-type amino acid transport system, permease component	397
2904474130	341	91.17	1	269	5	262	5.7e-44	144.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904474132	306	99.35	1	306	2	307	4.3e-114	375.1	COG1560	Lauroyl/myristoyl acyltransferase	308
2904474133	142	87.5	6	138	10	135	1.1e-19	65.4	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2904474134	98	100	1	98	1	98	1.4e-54	177	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
2904474135	286	87.38	1	286	39	322	4.3e-102	335.9	COG0042	tRNA-dihydrouridine synthase	323
2904474136	250	96.4	1	250	7	247	6.1e-90	295.3	COG3338	Carbonic anhydrase	250
2904474137	294	99.34	1	293	2	303	1.4e-105	347.4	COG2264	Ribosomal protein L11 methylase PrmA	300
2904474138	481	99.37	3	476	2	471	0.0e+00	766.3	COG4145	Na+/panthothenate symporter	473
2904474139	82	98.75	3	82	1	79	2.1e-39	128.3	COG3924	Uncharacterized membrane protein YhdT	80
2904474140	449	99.11	1	448	1	446	0.0e+00	700.1	COG0439	Biotin carboxylase	449
2904474141	154	99.32	6	154	1	146	5.2e-48	157.9	COG0511	Biotin carboxyl carrier protein	140
2904474142	150	97.95	5	150	2	144	4.8e-66	215.1	COG0757	3-dehydroquinate dehydratase	146
2904474143	200	92.45	2	200	5	200	2.6e-69	227.4	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
2904474144	333	96.19	18	306	5	282	1.5e-93	307.2	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2904474145	644	96.89	394	644	5	253	3.3e-46	151.2	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2904474145	644	97.27	205	383	5	182	3.6e-19	62.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904474146	347	99.12	5	346	2	339	0.0e+00	528.9	COG1077	Actin-like ATPase involved in cell morphogenesis	342
2904474147	335	99.65	3	296	1	285	2.2e-102	336.2	COG1792	Cell shape-determining protein MreC	284
2904474148	162	96.41	2	162	3	163	1.7e-58	191.5	COG2891	Cell shape-determining protein MreD	167
2904474149	197	95.88	1	189	2	187	1.7e-68	224	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
2904474150	489	98.77	2	489	3	485	0.0e+00	624.8	COG1530	Ribonuclease G or E	487
2904474151	1275	99.84	1	1271	2	1270	0.0e+00	1551.2	COG3164	Uncharacterized conserved protein YhdP, contains DUF3971 and AsmA2 domains	1271
2904474153	481	99.34	15	480	3	455	0.0e+00	526.2	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2904474154	312	98.34	2	297	2	297	1.9e-69	228.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904474156	293	90.62	1	287	26	344	1.3e-82	270.4	COG1566	Multidrug resistance efflux pump	352
2904474157	652	96.94	2	652	10	674	3.9e-129	426.1	COG1289	Uncharacterized membrane protein YccC	674
2904474158	193	95.79	11	192	2	183	4.4e-52	170.9	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2904474159	486	98.33	16	485	3	473	0.0e+00	585.7	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2904474161	99	98.9	3	90	1	90	1.6e-30	99.4	COG2732	Barstar, RNAse (barnase) inhibitor	91
2904474162	183	97.86	1	183	1	183	2.2e-84	276	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
2904474163	446	99.34	12	446	3	455	0.0e+00	451.3	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2904474164	128	100	29	128	1	100	6.9e-34	110.7	COG3783	Soluble cytochrome b562	100
2904474165	136	71.71	2	127	44	152	2.5e-25	83.5	COG0782	Transcription elongation factor, GreA/GreB family	151
2904474171	377	92.75	2	377	18	375	0.0e+00	462.4	COG3964	Predicted amidohydrolase	386
2904474172	375	91.14	1	374	11	370	5.1e-91	299.7	COG1921	Seryl-tRNA(Sec) selenium transferase	395
2904474174	639	88.8	4	520	6	449	1.3e-89	295.6	COG3711	Transcriptional antiterminator	491
2904474175	90	97.75	2	90	2	88	1.3e-31	102.9	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
2904474176	284	99.65	1	282	1	285	2.6e-124	408.5	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
2904474177	156	97.37	8	156	2	149	6.9e-42	137	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
2904474178	95	88.18	1	95	1	97	3.1e-39	128.1	COG1544	Ribosome-associated translation inhibitor RaiA	110
2904474179	477	99.78	1	477	1	447	0.0e+00	590.4	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
2904474180	241	99.18	1	241	3	243	6.5e-122	399.6	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
2904474181	185	95.38	5	177	5	169	1.2e-60	198	COG1934	Lipopolysaccharide export system protein LptA	173
2904474182	189	96.79	2	188	6	186	8.4e-60	196	COG3117	Lipopolysaccharide export system protein LptC	188
2904474183	188	98.82	19	188	2	169	1.1e-77	253.7	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
2904474184	328	27.27	200	265	130	180	9.7e-05	3.5	COG3620	Predicted transcriptional regulator with C-terminal CBS domains	187
2904474184	328	28.34	256	327	65	117	9.7e-05	11.4	COG3620	Predicted transcriptional regulator with C-terminal CBS domains	187
2904474184	328	99.5	12	212	2	202	1.4e-86	283	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
2904474185	325	97.89	1	319	8	331	2.7e-83	273.8	COG0530	Ca2+/Na+ antiporter	320
2904474186	267	98.86	1	262	2	261	4.6e-110	361.2	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
2904474187	260	96.25	1	260	8	264	9.2e-103	337.4	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2904474188	186	42.7	1	179	1	158	5.7e-49	161.4	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2904474189	211	98.51	1	201	3	201	3.4e-81	266.1	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
2904474190	104	97.98	1	97	1	97	4.5e-32	104.6	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
2904474191	84	100	1	80	1	80	2.1e-41	134.4	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
2904474192	419	99.52	1	419	1	419	0.0e+00	642.6	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
2904474193	350	98.08	1	350	4	361	1.9e-102	337.4	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2904474194	456	22.74	362	453	266	348	0.0e+00	35.7	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2904474194	456	96.16	4	367	11	361	0.0e+00	401.3	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2904474195	133	93.48	1	132	6	134	1.2e-59	194.5	COG3105	Uncharacterized membrane-anchored protein YhcB, DUF1043 family	138
2904474196	379	97.58	1	378	9	371	0.0e+00	468.5	COG1485	Predicted ATPase	367
2904474197	142	96.62	1	142	1	143	3.9e-67	219	COG0102	Ribosomal protein L13	148
2904474198	130	96.24	1	130	6	133	7.2e-58	189	COG0103	Ribosomal protein S9	130
2904474199	213	99.07	11	210	1	213	4.7e-49	161.4	COG0625	Glutathione S-transferase	211
2904474200	162	98.71	1	162	3	155	3.1e-70	229.6	COG2969	Stringent starvation protein B	155
2904474201	472	97.82	23	472	3	450	0.0e+00	572.5	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2904474202	1485	99.34	1178	1485	2	303	1.7e-107	353.3	COG0070	Glutamate synthase domain 3	301
2904474202	1485	99.46	1	376	2	371	0.0e+00	494.6	COG0067	Glutamate synthase domain 1	371
2904474202	1485	99.59	692	1173	2	488	0.0e+00	691.3	COG0069	Glutamate synthase domain 2	485
2904474203	779	46.95	3	167	69	253	3.2e-72	2.6	COG0642	Signal transduction histidine kinase	336
2904474203	779	57.92	524	667	7	123	1.3e-08	29	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2904474203	779	62.94	235	511	138	385	3.2e-72	236.5	COG0642	Signal transduction histidine kinase	336
2904474203	779	90.4	661	778	3	115	3.5e-23	76.8	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2904474204	240	28.47	8	239	61	263	9.3e-70	230.1	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2904474205	191	96.45	1	191	7	196	1.0e-64	212.7	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2904474206	196	98.87	1	179	2	176	2.1e-78	256.4	COG0279	Phosphoheptose isomerase	176
2904474207	122	98.25	8	121	2	113	4.1e-40	130.6	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
2904474208	678	99.34	1	677	5	605	0.0e+00	766.5	COG3107	Outer membrane lipoprotein LpoA, binds and activates PBP1a	604
2904474209	289	98.9	9	285	3	271	5.8e-109	357.6	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
2904474212	234	88.21	1	234	1	247	2.8e-47	155.8	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2904474213	301	98.01	7	300	2	296	2.4e-50	166.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904474214	327	99.69	1	326	1	321	0.0e+00	507.4	COG0435	Glutathionyl-hydroquinone reductase	324
2904474215	130	92.36	1	130	9	141	1.6e-36	120.2	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2904474217	135	95.42	1	133	6	130	7.3e-49	159.4	COG5393	Uncharacterized membrane protein YqjE	131
2904474218	100	93.27	1	100	8	104	4.9e-39	127.6	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2904474219	126	15.84	26	125	507	602	9.1e-02	5.2	COG0443	Molecular chaperone DnaK (HSP70)	579
2904474221	226	94.71	13	219	9	205	2.5e-59	194.4	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2904474222	258	96.68	1	234	5	237	1.5e-66	218.4	COG2186	DNA-binding transcriptional regulator, FadR family	241
2904474223	430	92.22	3	420	25	439	1.5e-36	120.3	COG2271	Sugar phosphate permease	448
2904474224	470	99.78	3	467	1	463	0.0e+00	718.3	COG1904	Glucuronate isomerase	463
2904474225	483	98.95	1	482	6	474	0.0e+00	444	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
2904474226	496	19.6	1	95	142	219	0.0e+00	5.2	COG2721	Altronate dehydratase	381
2904474226	496	99.5	102	496	3	398	0.0e+00	560.2	COG2721	Altronate dehydratase	381
2904474227	184	69.49	30	127	32	113	1.4e-03	13.1	COG3080	Fumarate reductase subunit D	118
2904474228	559	88.78	75	537	48	506	7.6e-51	168	COG0366	Glycosidase	505
2904474229	397	90.74	1	397	40	441	3.7e-46	152.7	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2904474230	293	95.64	2	292	6	290	4.9e-77	253.4	COG1175	ABC-type sugar transport system, permease component	295
2904474231	281	98.23	1	280	6	283	1.7e-79	261.5	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2904474232	350	100	1	350	1	353	1.3e-49	161.3	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2904474233	263	98.56	1	263	3	276	7.2e-46	151.1	COG1082	Sugar phosphate isomerase/epimerase	274
2904474234	352	98.58	8	352	3	348	3.4e-83	274.2	COG0673	Predicted dehydrogenase	342
2904474235	748	96.77	1	739	9	756	0.0e+00	768.4	COG1554	Trehalose and maltose hydrolase (possible phosphorylase)	772
2904474236	227	97.29	6	225	3	217	5.1e-50	164.7	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2904474237	362	99.43	1	354	1	348	0.0e+00	488.8	COG3839	ABC-type sugar transport system, ATPase component	338
2904474239	343	98.8	3	340	1	330	6.4e-93	305.9	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904474240	243	93.73	1	243	1	239	7.7e-113	370.2	COG3484	Predicted proteasome-type protease	255
2904474241	264	89.35	1	263	11	312	1.9e-46	153.2	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2904474242	313	98.72	1	313	1	309	5.0e-82	270.2	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2904474243	467	95.29	1	467	19	483	0.0e+00	686.8	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
2904474244	128	94.85	1	128	6	134	2.6e-42	138.3	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2904474245	154	99.35	1	153	1	152	1.7e-62	203.9	COG1781	Aspartate carbamoyltransferase, regulatory subunit	153
2904474246	314	99.05	4	313	2	313	1.9e-119	392.6	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
2904474248	168	96	8	156	3	146	3.0e-34	112.4	COG1438	Arginine repressor	150
2904474249	467	97.93	1	467	8	481	0.0e+00	592.2	COG1288	Uncharacterized membrane protein YfcC, ion transporter superfamily	481
2904474250	335	99.04	2	333	3	310	0.0e+00	442.3	COG0078	Ornithine carbamoyltransferase	310
2904474251	303	99.04	4	302	3	311	1.1e-115	380.2	COG0549	Carbamate kinase	312
2904474252	406	99.26	1	406	4	407	0.0e+00	493.4	COG2235	Arginine deiminase	409
2904474253	157	98.7	2	155	1	152	1.3e-50	165.4	COG2731	Beta-galactosidase, beta subunit	154
2904474254	600	86.85	86	561	51	499	1.5e-39	130.5	COG0366	Glycosidase	505
2904474255	335	98.71	1	333	4	310	0.0e+00	446.2	COG0078	Ornithine carbamoyltransferase	310
2904474256	141	99.26	4	141	2	135	1.3e-67	220.5	COG3076	Regulator of RNase E activity RraB	135
2904474257	477	98.7	2	477	2	458	0.0e+00	633.6	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2904474258	510	93.26	6	92	2	84	1.5e-26	86	COG1264	Phosphotransferase system IIB components	88
2904474258	510	95.71	91	509	4	405	2.0e-60	199.1	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
2904474259	246	90.07	1	246	10	263	3.5e-63	207.6	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2904474260	167	80.42	4	151	13	164	6.1e-17	56.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2904474261	396	98.63	1	396	5	363	8.6e-114	372.5	COG4269	Uncharacterized membrane protein YjgN, DUF898 family	364
2904474262	341	66.03	46	341	103	308	4.5e-25	82.8	COG0501	Zn-dependent protease with chaperone function	302
2904474263	171	98.93	1	171	3	187	1.2e-27	91.3	COG3539	Pilin (type 1 fimbria component protein)	184
2904474264	169	100	1	169	1	187	4.2e-23	76.6	COG3539	Pilin (type 1 fimbria component protein)	184
2904474265	229	94.14	1	228	13	237	5.9e-66	216.4	COG3121	P pilus assembly protein, chaperone PapD	235
2904474266	871	98.81	25	871	11	838	0.0e+00	909.1	COG3188	Outer membrane usher protein FimD/PapC	835
2904474267	318	86.63	142	318	26	187	1.6e-15	52	COG3539	Pilin (type 1 fimbria component protein)	184
2904474268	343	98.34	41	343	1	296	1.5e-32	107.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904474269	951	99.66	1	950	2	881	0.0e+00	1277.4	COG0525	Valyl-tRNA synthetase	877
2904474270	161	97.22	1	148	1	140	2.3e-46	151.6	COG2927	DNA polymerase III, chi subunit	144
2904474271	503	99.79	1	498	1	486	0.0e+00	611.2	COG0260	Leucyl aminopeptidase	485
2904474272	364	98.63	1	352	3	362	3.4e-101	333.3	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
2904474273	356	99.18	2	356	2	363	7.2e-113	371.7	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
2904474274	375	91.34	2	372	11	379	6.5e-69	227.2	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2904474276	306	93.71	2	306	16	313	6.6e-75	246.9	COG0657	Acetyl esterase/lipase	312
2904474278	378	91.67	4	374	8	337	1.3e-33	110.5	COG3203	Outer membrane protein (porin)	354
2904474281	424	78.36	39	422	58	401	2.6e-81	267.2	COG4268	5-methylcytosine-specific restriction endonuclease McrBC, regulatory subunit McrC	439
2904474282	523	4.85	182	220	305	334	3.0e-41	8.1	COG1401	5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB	601
2904474282	523	12.92	26	162	93	172	3.0e-41	3.6	COG1401	5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB	601
2904474282	523	13.09	327	467	511	591	3.0e-41	63.5	COG1401	5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB	601
2904474282	523	17.61	215	330	267	375	3.0e-41	55.3	COG1401	5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB	601
2904474283	558	96.94	11	556	4	541	0.0e+00	513.1	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2904474284	260	98.72	26	259	4	234	5.5e-86	282	COG3527	Alpha-acetolactate decarboxylase	234
2904474285	290	94.02	1	287	1	283	4.1e-68	224.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904474286	165	60.8	22	164	76	196	9.4e-38	124.6	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2904474287	426	95.08	224	415	9	182	1.0e-50	165.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904474289	427	98.08	11	427	4	411	2.7e-125	412.6	COG0814	Amino acid permease	415
2904474290	455	28	2	97	50	126	2.1e-125	20	COG1760	L-serine deaminase	262
2904474290	455	100	169	450	1	275	2.1e-125	391.4	COG1760	L-serine deaminase	262
2904474291	550	68.9	342	549	3	228	2.3e-92	17.9	COG2376	Dihydroxyacetone kinase	323
2904474291	550	99.09	2	330	2	326	2.3e-92	291.8	COG2376	Dihydroxyacetone kinase	323
2904474293	724	99.4	48	669	1	495	0.0e+00	587.9	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
2904474294	104	100	1	104	1	105	1.3e-44	145	COG3254	L-rhamnose mutarotase	105
2904474295	382	99.21	2	382	4	379	0.0e+00	462.3	COG1454	Alcohol dehydrogenase, class IV	377
2904474296	274	96.88	5	273	6	222	1.0e-64	212.3	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2904474297	418	99.76	1	418	1	418	0.0e+00	811.6	COG4806	L-rhamnose isomerase	419
2904474298	494	97.21	1	493	2	489	2.1e-103	341	COG1070	Sugar (pentulose or hexulose) kinase	502
2904474299	275	80.3	151	275	20	125	4.4e-29	94.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904474300	290	93.94	149	281	4	127	6.4e-26	84.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904474302	291	97.81	97	275	4	182	2.5e-50	165.3	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904474307	312	98.01	2	300	3	297	2.1e-67	222.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904474308	330	97.81	1	316	1	313	6.9e-112	367.7	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2904474309	348	97.68	37	337	7	301	1.5e-103	340.2	COG2813	16S rRNA G1207 methylase RsmC	300
2904474310	137	99.25	2	133	2	133	2.8e-53	173.9	COG3050	DNA polymerase III, psi subunit	133
2904474311	147	91.01	1	147	12	183	6.6e-33	108.6	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2904474312	107	27.81	1	84	7	58	1.3e-11	38.9	COG3620	Predicted transcriptional regulator with C-terminal CBS domains	187
2904474314	529	99.43	2	529	4	528	0.0e+00	906.4	COG4108	Peptide chain release factor RF-3	528
2904474316	197	98.48	1	197	3	196	1.9e-56	185.7	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2904474317	53	96.3	1	53	1	52	2.8e-27	89.1	COG5487	Uncharacterized membrane protein YtjA, UPF0391 family	54
2904474318	410	98.97	14	309	2	290	9.7e-121	396.8	COG4667	Predicted phospholipase, patatin/cPLA2 family	292
2904474319	261	98.83	3	258	3	256	3.2e-70	230.6	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
2904474321	259	96.93	4	255	4	224	3.4e-82	269.5	COG0274	Deoxyribose-phosphate aldolase	228
2904474322	442	99.31	1	439	3	435	0.0e+00	600	COG0213	Thymidine phosphorylase	435
2904474323	407	98.99	1	407	1	393	0.0e+00	613.3	COG1015	Phosphopentomutase	397
2904474324	239	99.15	1	236	1	234	3.5e-120	393.8	COG0813	Purine-nucleoside phosphorylase	236
2904474325	448	48.31	1	91	30	86	9.4e-04	12.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2904474326	262	98.61	1	218	1	213	7.6e-94	307.3	COG3726	Uncharacterized membrane protein affecting hemolysin expression	214
2904474327	321	98.58	107	317	3	211	1.2e-73	241.5	COG0560	Phosphoserine phosphatase	212
2904474328	460	98.9	1	460	4	454	0.0e+00	669.9	COG1066	Predicted ATP-dependent serine protease	456
2904474329	419	98.93	224	412	1	185	1.0e-89	293.2	COG3172	Nicotinamide riboside kinase	187
2904474329	419	99.42	62	224	2	173	4.2e-53	173.3	COG1056	Nicotinamide mononucleotide adenylyltransferase	172
2904474332	333	97.58	3	333	8	330	1.2e-71	235.9	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2904474333	302	97.34	4	295	3	295	1.2e-74	246	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904474334	555	99.44	3	537	3	534	0.0e+00	584.4	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2904474335	226	67.5	134	198	18	71	1.8e-14	45.2	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2904474336	912	95.96	1	911	35	961	0.0e+00	843.4	COG0474	Magnesium-transporting ATPase (P-type)	917
2904474337	642	99.34	344	635	2	302	4.1e-68	224.8	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2904474338	111	94.17	6	108	5	101	1.7e-42	138.2	COG2973	Trp operon repressor	103
2904474339	177	98.86	1	173	1	173	2.0e-61	201.2	COG1986	Non-canonical (house-cleaning) NTP pyrophosphatase, all-alpha NTP-PPase family	175
2904474340	215	96.65	1	209	2	203	5.4e-56	183.8	COG0406	Broad specificity phosphatase PhoE	208
2904474341	287	78.03	1	128	24	126	2.1e-27	89.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904474341	287	96.18	127	287	4	154	1.0e-06	22.8	COG3708	Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain	157
2904474342	160	89.7	1	160	10	157	4.8e-72	235.1	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
2904474343	238	98.71	4	235	2	230	4.7e-71	232.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904474344	228	95.97	1	228	4	241	3.9e-70	230.5	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
2904474346	819	98.8	463	819	2	331	2.1e-104	342.8	COG0460	Homoserine dehydrogenase	333
2904474346	819	99.1	1	462	4	442	0.0e+00	480.7	COG0527	Aspartokinase	447
2904474347	309	98.67	1	309	3	299	2.7e-106	349.3	COG0083	Homoserine kinase	299
2904474348	429	99.52	1	426	1	417	0.0e+00	439.3	COG0498	Threonine synthase	411
2904474349	257	99.6	1	257	1	252	5.1e-107	351.4	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
2904474350	475	98.89	1	448	4	450	0.0e+00	510	COG1115	Na+/alanine symporter	452
2904474351	317	99.34	5	315	2	303	2.2e-115	379.7	COG0176	Transaldolase	239
2904474352	195	95.88	1	178	7	169	2.4e-62	203.6	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
2904474353	440	50.91	239	436	8	202	3.3e-30	12.2	COG0477	MFS family permease	338
2904474353	440	74.93	10	284	3	289	3.3e-30	93.4	COG0477	MFS family permease	338
2904474354	181	84.54	1	170	32	206	4.7e-70	229.5	COG1584	Succinate-acetate transporter protein	207
2904474355	633	99.01	1	605	6	605	0.0e+00	845.3	COG0443	Molecular chaperone DnaK (HSP70)	579
2904474357	377	99.74	1	374	1	384	0.0e+00	520	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2904474358	391	98.47	1	391	4	390	0.0e+00	555.5	COG3004	Na+/H+ antiporter NhaA	390
2904474359	274	89.04	1	271	20	287	1.0e-34	114.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904474360	87	97.73	1	87	1	86	3.8e-35	114.7	COG0268	Ribosomal protein S20	88
2904474362	295	94.14	1	290	18	306	4.9e-115	378.1	COG0196	FAD synthase	304
2904474363	938	99.68	2	932	2	945	0.0e+00	1203.6	COG0060	Isoleucyl-tRNA synthetase	933
2904474364	168	94.61	1	167	5	162	7.3e-54	175.9	COG0597	Lipoprotein signal peptidase	167
2904474365	156	82.49	3	155	2	147	1.0e-49	162.6	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
2904474366	317	96.27	1	296	2	285	7.1e-127	416.7	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
2904474367	291	94.82	3	286	17	309	6.0e-48	157.6	COG3386	Sugar lactone lactonase YvrE	307
2904474368	381	98.89	6	381	5	360	8.6e-42	137.6	COG3203	Outer membrane protein (porin)	354
2904474369	273	99.63	4	270	2	267	5.6e-108	354.7	COG0289	Dihydrodipicolinate reductase	266
2904474370	383	99.19	2	380	2	369	0.0e+00	540.5	COG0505	Carbamoylphosphate synthase small subunit	368
2904474371	1074	96.1	565	952	1	394	0.0e+00	302	COG0458	Carbamoylphosphate synthase large subunit	400
2904474371	1074	99.51	13	428	1	408	0.0e+00	734.4	COG0458	Carbamoylphosphate synthase large subunit	400
2904474374	184	97.38	1	172	3	188	3.4e-50	164.8	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
2904474375	617	73.09	390	587	28	190	9.0e-32	103.5	COG1226	Voltage-gated potassium channel Kch	212
2904474375	617	96.75	2	394	6	392	3.6e-99	326.3	COG0475	Kef-type K+ transport system, membrane component KefB	397
2904474376	204	98.08	1	204	2	205	6.4e-57	186.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2904474377	269	97.2	10	255	8	250	2.5e-86	283	COG2966	Uncharacterized membrane protein YjjP, DUF1212 family	250
2904474378	154	98.08	2	154	2	154	4.9e-53	173.6	COG3610	Uncharacterized membrane protein YjjB, DUF3815 family	156
2904474379	161	98.82	2	160	2	169	3.6e-52	170.9	COG0262	Dihydrofolate reductase	167
2904474380	284	100	69	264	1	158	2.5e-29	96.9	COG0639	Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family	155
2904474381	125	97.62	1	125	3	125	7.6e-59	191.5	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
2904474382	275	97.31	9	269	5	257	3.5e-93	305.7	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
2904474383	335	98.79	6	334	3	329	0.0e+00	436.3	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
2904474384	431	47.38	274	428	164	317	1.6e-117	180.6	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2904474384	431	81.85	4	280	3	268	1.6e-117	211.4	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2904474385	791	99.75	6	791	3	796	0.0e+00	820.1	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
2904474386	273	100	69	267	1	174	7.0e-68	222.3	COG1076	DnaJ-domain-containing proteins 1	174
2904474387	1258	60.94	334	722	14	414	8.7e-35	99.8	COG3468	Type V secretory pathway, adhesin AidA	644
2904474387	1258	81	637	1212	37	569	8.7e-35	6.3	COG3468	Type V secretory pathway, adhesin AidA	644
2904474388	233	77.4	1	233	65	290	3.2e-79	260.7	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2904474389	965	88.11	49	881	2	794	2.9e-104	344.3	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
2904474390	780	96.83	1	780	15	778	0.0e+00	518	COG0417	DNA polymerase elongation subunit (family B)	792
2904474391	255	93.27	2	206	12	205	2.4e-50	165.3	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2904474392	236	99.57	1	231	1	230	2.4e-109	358.4	COG3840	ABC-type thiamine transport system, ATPase component	231
2904474393	536	98.53	1	536	4	539	0.0e+00	506.8	COG1178	ABC-type Fe3+ transport system, permease component	540
2904474394	327	97.63	1	327	8	337	0.0e+00	473.9	COG4143	ABC-type thiamine transport system, periplasmic component	336
2904474396	553	100	1	550	1	564	0.0e+00	666.6	COG4533	DNA-binding transcriptional regulator SgrR  of sgrS sRNA, contains a MarR-type HTH domain and a periplasmic-type solute-binding domain	564
2904474398	387	48.04	203	385	8	191	1.6e-21	38.5	COG0477	MFS family permease	338
2904474398	387	58.22	4	231	8	230	1.6e-21	37.1	COG0477	MFS family permease	338
2904474400	200	99.48	1	200	1	192	7.4e-85	277.9	COG0066	3-isopropylmalate dehydratase small subunit	191
2904474401	466	99.53	1	466	2	428	0.0e+00	662.8	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
2904474402	363	99.14	2	362	2	346	0.0e+00	468.1	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2904474403	529	99.52	3	414	2	412	0.0e+00	518.5	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2904474405	315	97.01	22	314	2	293	4.1e-43	142.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904474406	598	97.39	1	598	13	609	0.0e+00	623	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2904474407	572	99.82	3	568	1	554	0.0e+00	772.9	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2904474408	163	98.77	1	162	3	162	4.9e-68	222.3	COG0440	Acetolactate synthase, small subunit	163
2904474409	334	98.5	1	334	2	330	4.6e-80	263.7	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904474410	152	98.63	1	152	1	144	2.6e-56	183.7	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
2904474411	313	98.73	1	313	3	313	1.9e-125	412.9	COG0275	16S rRNA C1402 N4-methylase RsmH	314
2904474412	106	98.08	2	105	3	104	9.3e-45	145.3	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
2904474413	587	99.21	7	566	4	630	0.0e+00	475.7	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2904474414	495	99.38	4	494	2	482	0.0e+00	593.3	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
2904474415	453	99.56	2	450	2	453	0.0e+00	537.9	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
2904474416	360	98.77	20	360	2	323	3.6e-118	388.6	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2904474417	438	99.33	1	438	2	448	0.0e+00	494.6	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
2904474418	401	95.55	11	395	12	376	0.0e+00	431.1	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
2904474419	355	99.16	6	355	2	356	7.5e-129	424.2	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
2904474420	491	99.13	13	481	3	459	0.0e+00	609.4	COG0773	UDP-N-acetylmuramate-alanine ligase	459
2904474421	306	99.06	1	306	3	317	2.7e-106	349.5	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
2904474422	278	98.52	1	269	3	269	6.8e-82	269	COG1589	Cell division septal protein FtsQ	269
2904474423	418	99.31	1	418	4	434	0.0e+00	530.2	COG0849	Cell division ATPase FtsA	418
2904474424	384	91.38	1	369	4	321	0.0e+00	471.1	COG0206	Cell division GTPase FtsZ	338
2904474425	305	99.34	1	302	1	299	0.0e+00	475	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
2904474426	174	98.15	2	163	2	160	1.3e-57	188.6	COG4701	Uncharacterized protein	162
2904474428	905	99.88	2	897	2	840	0.0e+00	1305.3	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
2904474429	133	75	3	130	19	147	4.0e-24	79.8	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2904474430	65	98.46	1	65	1	64	1.4e-32	105.8	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
2904474431	250	100	7	250	1	244	1.0e-121	399.4	COG4582	Cell division protein ZapD, interacts with FtsZ	244
2904474432	198	98.01	1	198	1	197	6.8e-66	216.3	COG0237	Dephospho-CoA kinase	201
2904474433	347	33.03	1	113	14	85	2.5e-47	22	COG0516	IMP dehydrogenase/GMP reductase	170
2904474433	347	93.58	138	343	4	207	2.5e-47	131.3	COG0516	IMP dehydrogenase/GMP reductase	170
2904474434	406	99.25	11	406	3	397	3.6e-119	392.3	COG1459	Type II secretory pathway, component PulF	397
2904474435	498	97.05	6	494	15	507	0.0e+00	577.2	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2904474436	148	100	1	134	1	128	1.3e-30	100.6	COG4969	Tfp pilus assembly protein, major pilin PilA	125
2904474437	297	97.5	18	297	5	277	3.1e-107	352.1	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
2904474438	190	67.43	1	183	3	178	2.6e-66	217.8	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
2904474439	284	100	1	284	1	282	5.1e-113	371.4	COG3725	Membrane protein required for beta-lactamase induction	282
2904474440	324	97.53	1	322	2	317	0.0e+00	572.4	COG3940	Beta-xylosidase, GH43 family	324
2904474441	480	97.42	1	465	5	457	0.0e+00	511.8	COG2211	Na+/melibiose symporter or related transporter	467
2904474442	456	97.4	1	456	5	454	0.0e+00	628.7	COG1113	L-asparagine transporter and related permeases	462
2904474443	256	97.1	1	242	6	239	2.0e-66	218.2	COG2186	DNA-binding transcriptional regulator, FadR family	241
2904474445	887	99.89	1	887	1	886	0.0e+00	1580.2	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
2904474446	632	25.12	106	211	3	111	0.0e+00	93.9	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2904474446	632	26.73	1	111	1	116	0.0e+00	99	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2904474446	632	99.31	208	632	3	433	0.0e+00	483.8	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2904474447	474	99.56	3	456	3	455	0.0e+00	561.2	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2904474449	370	97.1	75	369	2	302	1.6e-47	156	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2904474450	276	74.17	7	271	11	211	2.4e-39	129.8	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2904474451	363	98.87	1	354	4	352	2.1e-120	396.6	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2904474452	287	93.4	1	286	11	279	1.9e-52	172.8	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2904474453	278	95.51	3	275	6	260	2.3e-63	208.2	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2904474454	362	97.92	1	362	6	381	6.4e-91	299.6	COG4134	ABC-type uncharacterized transport system YnjBCD, periplasmic component	384
2904474455	174	100	1	174	1	187	2.3e-42	139.4	COG3539	Pilin (type 1 fimbria component protein)	184
2904474456	213	86.19	1	211	31	236	3.3e-73	240.3	COG3121	P pilus assembly protein, chaperone PapD	235
2904474457	813	96.66	2	813	29	838	0.0e+00	881.4	COG3188	Outer membrane usher protein FimD/PapC	835
2904474458	327	66.31	11	158	43	166	5.8e-27	8.8	COG3539	Pilin (type 1 fimbria component protein)	184
2904474458	327	85.56	151	327	27	186	5.8e-27	85.6	COG3539	Pilin (type 1 fimbria component protein)	184
2904474461	865	99.77	1	861	2	851	0.0e+00	1590.8	COG1049	Aconitase B	852
2904474462	121	98.35	1	120	1	119	2.8e-56	183.3	COG3112	Uncharacterized protein YacL, UPF0231 family	121
2904474463	296	96.35	1	293	7	296	6.7e-37	121.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2904474465	264	100	3	183	1	137	5.6e-56	182.2	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
2904474466	291	98.94	7	289	2	280	6.4e-115	377.4	COG0421	Spermidine synthase	282
2904474468	534	99.59	3	534	1	482	0.0e+00	433.7	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904474469	182	100	1	176	1	176	4.2e-91	298	COG3730	Phosphotransferase system sorbitol-specific component IIC	176
2904474470	321	99.09	1	321	4	328	0.0e+00	535.5	COG3732	Phosphotransferase system sorbitol-specific component IIBC	328
2904474471	120	95.93	1	120	2	119	3.3e-49	160.2	COG3731	Phosphotransferase system sorbitol-specific component IIA	123
2904474472	259	98.13	1	258	5	267	4.0e-55	181.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904474473	120	89.84	1	120	8	122	5.8e-34	111.6	COG4578	DNA-binding transcriptional regulator of glucitol operon	128
2904474474	257	99.21	1	253	1	252	7.3e-86	282.2	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2904474477	178	95.53	1	176	5	175	1.3e-79	260	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
2904474480	163	98.1	1	163	1	155	8.9e-36	117.6	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2904474481	110	87.5	3	68	4	59	1.4e-03	12.2	COG4068	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	64
2904474482	94	8.92	10	89	152	212	4.8e-04	12.6	COG5427	Uncharacterized membrane protein	684
2904474483	386	98.87	9	381	3	352	6.0e-105	345.1	COG3500	Phage protein D	350
2904474484	156	97.28	1	146	1	143	1.5e-54	177.9	COG3499	Phage protein U	147
2904474485	824	14.1	508	746	656	826	6.0e-31	33.8	COG5283	Phage-related tail protein	1213
2904474485	824	15.66	1	206	55	244	6.0e-31	71.6	COG5283	Phage-related tail protein	1213
2904474485	824	27.37	198	575	372	703	6.0e-31	2.3	COG5283	Phage-related tail protein	1213
2904474488	169	100	1	169	1	169	3.9e-61	200	COG3498	Phage tail tube protein FII	169
2904474489	389	21.15	1	91	3	101	0.0e+00	94.8	COG3497	Phage tail sheath protein FI	394
2904474489	389	65.38	87	387	160	465	0.0e+00	353.7	COG3497	Phage tail sheath protein FI	394
2904474491	831	25.55	165	365	271	420	1.7e-72	7.3	COG5301	Phage-related tail fibre protein	587
2904474491	831	33.22	1	212	4	198	1.7e-72	239.7	COG5301	Phage-related tail fibre protein	587
2904474492	175	85.92	1	175	2	178	2.4e-65	214.5	COG4385	Bacteriophage P2-related tail formation protein	206
2904474493	302	98.69	1	302	5	306	8.2e-126	413.6	COG3948	Phage-related baseplate assembly protein	306
2904474494	116	88.79	1	115	2	104	4.0e-38	124	COG3628	Phage baseplate assembly protein W	116
2904474495	213	96.74	13	212	1	178	2.4e-52	170.9	COG4540	Phage P2 baseplate assembly protein gpV	184
2904474500	152	76.43	5	149	24	130	3.3e-07	24.7	COG5005	Mu-like prophage protein gpG	140
2904474503	169	94.74	24	169	7	150	1.6e-42	139.1	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
2904474505	67	97.14	1	67	3	70	5.5e-30	97.4	COG5004	P2-like prophage tail protein X	70
2904474510	588	97.85	8	301	7	279	1.4e-55	182.7	COG5484	Uncharacterized protein YjcR	279
2904474511	343	25.61	2	142	29	154	6.2e-92	112.3	COG5518	Bacteriophage capsid portal protein	492
2904474511	343	49.39	138	342	191	433	6.2e-92	189.8	COG5518	Bacteriophage capsid portal protein	492
2904474514	102	50.77	2	101	5	70	8.6e-08	27.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2904474516	524	13.14	371	405	7	24	2.1e-03	1.9	COG1591	Holliday junction resolvase, archaeal type	137
2904474516	524	25.55	413	515	38	72	2.1e-03	7.6	COG1591	Holliday junction resolvase, archaeal type	137
2904474519	73	55	1	72	53	118	5.9e-11	37	COG1734	RNA polymerase-binding transcription factor DksA	120
2904474523	99	68.12	4	80	5	51	2.9e-04	14.9	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2904474524	335	17.33	250	321	241	292	8.1e-29	46.4	COG4974	Site-specific recombinase XerD	300
2904474524	335	47.33	83	240	51	192	8.1e-29	46.9	COG4974	Site-specific recombinase XerD	300
2904474525	218	99.52	1	203	1	207	3.5e-77	253.2	COG0288	Carbonic anhydrase	207
2904474526	307	99.67	1	302	1	305	1.2e-92	305.1	COG1131	ABC-type multidrug transport system, ATPase component	293
2904474527	256	92.49	1	255	22	292	2.4e-23	77.2	COG0842	ABC-type multidrug transport system, permease component	286
2904474528	126	96.83	2	126	2	123	2.9e-57	186.4	COG0853	Aspartate 1-decarboxylase	126
2904474529	284	98.6	1	283	3	283	6.7e-119	390.5	COG0414	Panthothenate synthetase	285
2904474530	264	97.76	3	264	3	264	1.1e-114	376.6	COG0413	Ketopantoate hydroxymethyltransferase	268
2904474531	228	98.71	1	219	1	229	4.4e-75	246.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904474532	461	80.46	94	460	67	383	9.0e-49	161.6	COG0642	Signal transduction histidine kinase	336
2904474533	159	95.65	1	159	1	154	1.0e-59	195.1	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
2904474534	568	95.18	137	556	2	396	0.0e+00	435.2	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
2904474535	291	62.92	1	291	8	309	2.2e-82	272.1	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2904474536	151	99.17	32	151	1	119	1.7e-46	152	COG1734	RNA polymerase-binding transcription factor DksA	120
2904474537	244	97.45	1	239	1	229	2.8e-97	319.1	COG1489	DNA-binding protein, stimulates sugar fermentation	235
2904474538	180	98.9	5	176	2	181	2.3e-41	136	COG1514	2'-5' RNA ligase	180
2904474539	814	93.92	1	812	53	870	0.0e+00	830	COG1643	HrpA-like RNA helicase	845
2904474540	879	99.44	130	865	2	710	0.0e+00	691.1	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2904474541	740	99.25	10	740	7	795	4.8e-125	413.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904474542	270	97.67	15	270	3	254	7.1e-94	308.2	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
2904474543	300	77.78	34	298	55	306	8.5e-38	124.6	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2904474544	662	96.72	345	662	8	331	0.0e+00	268.7	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2904474544	662	97.01	2	331	8	332	0.0e+00	211.3	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2904474545	426	98.38	1	426	4	428	0.0e+00	658.9	COG0001	Glutamate-1-semialdehyde aminotransferase	432
2904474546	474	98.2	4	453	7	443	1.1e-120	397.6	COG0038	H+/Cl- antiporter ClcA	443
2904474547	119	98.18	10	119	3	110	1.3e-44	145	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2904474549	270	82.41	11	268	52	318	6.6e-47	154.5	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2904474550	234	98.73	1	230	3	236	5.7e-84	275.5	COG0775	Nucleoside phosphorylase	234
2904474551	504	97.39	2	504	11	420	0.0e+00	447.1	COG0232	dGTP triphosphohydrolase	412
2904474552	483	22.47	393	481	266	347	0.0e+00	44.9	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2904474552	483	95.34	3	396	16	363	0.0e+00	416.3	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2904474553	386	99.2	4	385	2	374	0.0e+00	527.6	COG3835	Sugar diacid utilization regulator	376
2904474554	457	92.67	1	445	21	437	7.5e-38	124.8	COG2271	Sugar phosphate permease	448
2904474555	447	98.93	8	416	3	371	3.3e-88	290.3	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2904474556	445	99.2	7	414	2	371	3.7e-90	296.6	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2904474557	272	98.59	4	272	2	281	3.5e-75	247	COG0169	Shikimate 5-dehydrogenase	283
2904474558	217	96.5	2	211	3	195	1.2e-61	202.5	COG3145	Alkylated DNA repair dioxygenase AlkB	194
2904474559	159	95.52	1	63	2	65	1.6e-08	28.3	COG1278	Cold shock protein, CspA family	67
2904474560	322	52.87	18	167	81	172	4.8e-30	21.1	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2904474560	322	92.53	160	322	14	174	4.8e-30	85.3	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2904474561	815	92.48	35	803	63	837	4.3e-128	423	COG3188	Outer membrane usher protein FimD/PapC	835
2904474562	265	92.89	1	259	7	228	4.3e-44	144.7	COG3121	P pilus assembly protein, chaperone PapD	235
2904474563	181	87.93	3	181	22	174	1.3e-36	119.9	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2904474564	172	93.68	1	172	12	174	1.9e-44	146.2	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2904474565	181	94.83	3	181	10	174	1.1e-30	101.3	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2904474566	498	41.25	264	496	13	170	5.9e-28	8.8	COG0477	MFS family permease	338
2904474566	498	82.25	7	296	4	318	5.9e-28	86.2	COG0477	MFS family permease	338
2904474567	298	97.01	2	291	2	293	9.9e-81	266	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904474568	697	24.73	639	697	41	85	2.8e-10	30.1	COG3979	Chitodextrinase	181
2904474568	697	56.59	512	622	3	105	2.8e-10	15.3	COG3979	Chitodextrinase	181
2904474568	697	97.97	18	483	8	442	3.3e-109	359.5	COG3325	Chitinase, GH18 family	441
2904474569	115	50.68	1	90	35	109	6.1e-18	59	COG3710	DNA-binding winged helix-turn-helix (wHTH) domain	148
2904474570	180	66.01	2	179	6	172	2.4e-45	149.4	COG3926	Lysozyme family protein	252
2904474571	313	97.34	9	312	2	294	3.7e-30	100	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904474573	594	26.37	533	594	40	87	7.5e-44	28.4	COG3979	Chitodextrinase	181
2904474573	594	80.22	5	224	37	182	7.5e-44	121.3	COG3979	Chitodextrinase	181
2904474574	380	82.32	39	376	60	385	1.5e-70	232.4	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2904474575	274	91.67	31	272	19	227	5.8e-69	226.5	COG0765	ABC-type amino acid transport system, permease component	222
2904474576	272	93.99	1	270	10	275	2.0e-50	166	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904474577	219	94.3	2	219	14	228	3.9e-51	168.5	COG4291	Uncharacterized membrane protein	228
2904474579	212	96.63	1	206	6	206	2.0e-25	83.5	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2904474580	268	84.85	141	264	14	125	9.4e-23	74.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904474581	453	93.9	8	451	9	470	7.9e-73	239.8	COG0531	Amino acid transporter	466
2904474582	107	97.2	1	105	3	106	1.2e-07	26.4	COG4392	Branched-chain amino acid transport protein	107
2904474583	222	87.03	10	221	17	224	3.4e-45	148.6	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
2904474584	182	48.46	8	125	8	70	4.0e-16	54.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2904474587	84	56.41	6	84	18	83	6.5e-04	14.1	COG3462	Uncharacterized membrane protein	117
2904474588	321	98.19	1	320	6	331	9.7e-26	84.7	COG3274	Surface polysaccharide O-acyltransferase, integral membrane enzyme	332
2904474589	1021	99.61	2	1015	4	1013	0.0e+00	845.8	COG0841	Multidrug efflux pump subunit AcrB	1009
2904474590	361	92.56	5	354	19	379	1.8e-36	120.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904474591	903	95.65	2	901	37	960	0.0e+00	829.3	COG0474	Magnesium-transporting ATPase (P-type)	917
2904474593	157	57.5	88	149	20	65	6.0e-10	32.4	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2904474594	228	85.6	2	227	19	238	5.7e-21	68.8	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2904474600	476	96	241	476	10	225	9.2e-82	266.7	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2904474601	378	97.99	39	286	4	247	1.5e-78	257.7	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2904474602	144	99.32	1	143	2	148	4.1e-47	154.4	COG0394	Protein-tyrosine-phosphatase	139
2904474603	720	80.07	476	719	36	264	1.1e-47	156.3	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2904474603	720	96.34	1	452	6	453	8.2e-87	285.9	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2904474605	386	95.84	3	385	12	403	1.9e-31	104.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904474606	491	92.47	1	488	9	487	3.8e-42	138.6	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
2904474607	161	68.42	5	161	50	179	3.9e-33	109.2	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2904474608	387	50.12	4	382	137	341	4.0e-10	34.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904474610	473	93.02	345	471	9	128	1.6e-37	121.9	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2904474610	473	99.7	1	336	1	334	0.0e+00	470.1	COG0836	Mannose-1-phosphate guanylyltransferase	333
2904474611	459	96.65	1	459	11	472	1.2e-123	407.8	COG1109	Phosphomannomutase	464
2904474612	384	73.59	7	371	88	388	4.7e-34	113	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904474613	356	99.42	1	349	1	342	1.7e-116	383.4	COG1089	GDP-D-mannose dehydratase	345
2904474614	337	93.27	1	327	14	318	1.7e-58	192.3	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2904474615	535	89.88	122	521	43	424	1.3e-100	332.1	COG0840	Methyl-accepting chemotaxis protein	408
2904474616	434	95.95	19	429	15	417	3.6e-125	412.1	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
2904474617	320	97.53	1	314	8	323	1.2e-80	265.7	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2904474618	415	86.39	1	389	65	483	8.6e-89	292.8	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2904474619	253	98.44	3	253	3	255	2.9e-84	277	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2904474620	404	55.67	4	71	34	87	6.5e-03	10	COG1534	RNA-binding protein YhbY	97
2904474620	404	99.05	102	404	1	313	4.6e-75	246.8	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2904474621	309	83.95	1	275	2	252	8.5e-53	173.3	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2904474622	217	91.56	53	208	13	153	1.8e-41	135.7	COG2731	Beta-galactosidase, beta subunit	154
2904474623	438	91.78	2	434	24	436	3.5e-42	139	COG2271	Sugar phosphate permease	448
2904474626	720	99.66	100	719	2	592	0.0e+00	817.9	COG1982	Arginine/lysine/ornithine decarboxylase	557
2904474627	364	95.4	5	318	9	319	4.8e-56	184.8	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2904474628	376	95.98	41	286	9	247	7.1e-74	242.2	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2904474629	126	78.38	1	121	32	147	2.0e-24	80.8	COG0394	Protein-tyrosine-phosphatase	139
2904474630	716	79.37	477	715	40	266	7.5e-44	143.7	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2904474630	716	96.99	6	457	12	462	3.0e-78	257.6	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2904474631	371	76.35	1	363	5	372	3.1e-43	142.3	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2904474633	361	81.42	2	307	3	335	7.6e-28	92.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904474634	193	57.89	28	192	64	173	8.6e-17	53.3	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2904474635	394	72.37	1	388	87	382	9.1e-27	89.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904474637	377	72.13	10	376	111	405	1.2e-26	88.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904474638	359	99.34	46	353	2	302	2.1e-69	229	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2904474639	90	100	1	90	1	90	5.2e-51	165.1	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
2904474640	358	97.46	6	353	9	353	0.0e+00	459.1	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
2904474641	239	99.12	17	239	1	225	4.6e-86	282.4	COG0220	tRNA G46 methylase TrmB	227
2904474642	108	90.76	1	108	9	116	3.2e-53	173.4	COG3171	Uncharacterized conserved protein YggL, DUF469 family	119
2904474643	308	98.38	2	308	6	309	0.0e+00	447.3	COG2066	Glutaminase	309
2904474645	378	91.43	1	378	31	414	0.0e+00	438.2	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
2904474646	202	98.97	1	198	1	193	1.9e-75	247.1	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
2904474647	101	89.22	6	100	10	100	7.0e-34	110.1	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
2904474648	184	81.25	1	91	11	88	4.9e-41	49.6	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
2904474648	184	94.79	89	183	5	95	4.9e-41	90.4	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
2904474649	273	99.25	3	272	2	267	1.2e-87	288.1	COG0345	Pyrroline-5-carboxylate reductase	266
2904474650	239	99.56	7	235	2	229	5.2e-89	292.2	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
2904474651	340	94.33	1	340	3	335	0.0e+00	445.5	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
2904474652	142	97.16	3	142	2	138	1.8e-49	161.8	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
2904474653	187	94.85	1	187	11	194	3.6e-71	233	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
2904474654	316	99.05	2	315	1	312	1.6e-102	336.9	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2904474655	243	100	1	241	1	246	3.6e-87	286	COG1385	16S rRNA U1498 N3-methylase RsmE	246
2904474656	237	95.36	4	236	9	234	1.5e-110	362.7	COG2356	Endonuclease I	237
2904474657	150	89.74	1	146	14	153	1.3e-55	181.6	COG3091	Predicted Zn-dependent metalloprotease, SprT family	156
2904474658	464	41.51	284	459	46	204	7.7e-44	25.1	COG0477	MFS family permease	338
2904474658	464	84.33	14	311	7	329	7.7e-44	125.6	COG0477	MFS family permease	338
2904474659	249	92.89	1	245	13	234	1.5e-11	38	COG3121	P pilus assembly protein, chaperone PapD	235
2904474665	211	47.7	2	197	70	183	7.7e-08	26.1	COG3121	P pilus assembly protein, chaperone PapD	235
2904474666	383	98.71	1	383	4	387	0.0e+00	657.1	COG0192	S-adenosylmethionine synthetase	388
2904474667	660	99.39	6	659	4	651	0.0e+00	1038.7	COG1166	Arginine decarboxylase (spermidine biosynthesis)	652
2904474668	374	82.89	193	374	33	187	5.6e-20	66.6	COG3539	Pilin (type 1 fimbria component protein)	184
2904474669	193	97.86	1	193	5	187	4.4e-16	53.7	COG3539	Pilin (type 1 fimbria component protein)	184
2904474670	194	98.4	3	194	4	187	2.1e-14	48.2	COG3539	Pilin (type 1 fimbria component protein)	184
2904474671	192	93.05	3	192	14	187	2.1e-17	58	COG3539	Pilin (type 1 fimbria component protein)	184
2904474672	878	95.7	25	875	29	830	0.0e+00	808.9	COG3188	Outer membrane usher protein FimD/PapC	835
2904474673	244	96.65	2	244	7	237	2.1e-74	244.1	COG3121	P pilus assembly protein, chaperone PapD	235
2904474674	195	99.47	1	195	2	187	2.3e-20	67.7	COG3539	Pilin (type 1 fimbria component protein)	184
2904474675	250	89.74	1	250	29	308	1.1e-42	140.9	COG0501	Zn-dependent protease with chaperone function	302
2904474676	664	99.4	1	664	4	662	0.0e+00	1052.5	COG0021	Transketolase	663
2904474677	338	98.51	2	337	2	331	4.0e-130	428.3	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
2904474678	387	98.99	1	386	4	397	0.0e+00	515.8	COG0126	3-phosphoglycerate kinase	395
2904474679	359	98.61	12	359	3	286	2.6e-103	339.6	COG0191	Fructose/tagatose bisphosphate aldolase	286
2904474680	360	99.7	6	337	1	333	1.5e-95	314.6	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904474681	1032	99.52	40	926	3	837	0.0e+00	953.9	COG3250	Beta-galactosidase/beta-glucuronidase	808
2904474682	422	50.65	221	419	17	210	4.8e-16	16.7	COG0477	MFS family permease	338
2904474682	422	61.36	6	255	3	237	4.8e-16	41.3	COG0477	MFS family permease	338
2904474683	295	85.67	4	292	30	322	1.6e-73	242.1	COG0668	Small-conductance mechanosensitive channel	316
2904474684	205	99.5	1	202	1	201	5.7e-80	262.1	COG1279	Arginine exporter protein ArgO	202
2904474685	252	97.54	1	239	6	243	1.2e-83	274.9	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
2904474686	280	85.07	1	261	6	233	6.6e-50	164.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904474687	302	97.34	9	302	2	294	8.6e-73	240.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904474688	300	98.34	4	299	1	296	7.4e-46	151.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904474689	220	99.12	1	219	1	226	1.8e-84	276.8	COG0120	Ribose 5-phosphate isomerase	227
2904474690	412	99.08	8	336	2	324	1.7e-112	369.7	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2904474691	136	17.26	6	136	416	516	3.3e-01	4.5	COG2812	DNA polymerase III, gamma/tau subunits	515
2904474692	198	97.91	8	198	4	190	4.6e-60	197.3	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
2904474694	109	94.29	2	104	2	100	3.5e-34	111.5	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
2904474695	190	97.31	3	190	1	181	3.6e-82	269	COG3079	Uncharacterized conserved protein YgfB, UPF0149 family	186
2904474696	438	94.62	1	430	21	389	1.6e-103	341.1	COG0006	Xaa-Pro aminopeptidase	384
2904474697	392	99.24	1	391	3	392	6.1e-108	356.1	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2904474698	408	99.49	2	395	2	392	2.4e-118	390.3	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2904474699	365	97.92	1	364	4	380	7.3e-122	401.1	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
2904474700	128	96.95	1	128	3	129	6.7e-53	172.3	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
2904474701	957	21.73	244	381	242	349	0.0e+00	18.5	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2904474701	957	95.37	447	930	18	491	0.0e+00	739.3	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2904474702	247	98.13	1	247	5	267	2.0e-67	222	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904474703	285	99.21	1	264	1	252	5.1e-83	272.8	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2904474704	328	95.11	1	326	6	316	5.4e-64	210.4	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2904474705	510	98.8	7	510	4	498	0.0e+00	593.3	COG1129	ABC-type sugar transport system, ATPase component	500
2904474706	329	96.87	4	325	7	315	6.6e-84	275.7	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2904474707	361	96.55	22	349	7	314	2.0e-75	247.8	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2904474708	226	97.27	1	226	3	216	4.2e-72	236.2	COG0036	Pentose-5-phosphate-3-epimerase	220
2904474709	314	96.13	1	300	5	302	1.6e-48	159.7	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2904474710	310	98.42	5	307	1	311	1.7e-73	241.7	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2904474713	290	96.31	1	290	8	294	1.6e-76	252	COG1175	ABC-type sugar transport system, permease component	295
2904474714	299	96.47	15	299	11	283	3.1e-72	237.7	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2904474715	275	66.33	1	256	1	262	1.5e-23	78	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2904474716	369	99.43	2	356	1	348	0.0e+00	434.9	COG3839	ABC-type sugar transport system, ATPase component	338
2904474717	435	97.74	1	425	9	441	1.2e-66	220.3	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2904474718	202	74.74	12	182	5	149	2.4e-22	74.3	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
2904474719	216	91.88	2	216	17	231	5.6e-76	249	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
2904474720	430	95.18	1	428	6	420	0.0e+00	453	COG3486	Lysine/ornithine N-monooxygenase	436
2904474721	293	98.29	2	293	5	291	2.0e-70	231.9	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
2904474722	289	97.01	1	287	2	293	7.1e-53	174.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904474723	400	97.2	15	390	2	383	7.3e-79	259.9	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2904474724	264	97.53	1	262	2	277	2.3e-55	182.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904474726	184	86.15	6	148	2	113	2.3e-20	67.8	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2904474727	173	97.04	1	169	3	166	4.4e-56	183.8	COG1247	L-amino acid N-acyltransferase YncA	169
2904474728	365	95.24	16	203	6	185	8.3e-72	234.2	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
2904474728	365	97.02	202	364	5	167	4.3e-49	160.9	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2904474729	177	82.54	1	155	10	165	1.2e-18	61.9	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2904474730	234	88.24	19	207	21	185	3.2e-31	103.1	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2904474731	284	99.31	1	284	1	286	1.6e-104	343.6	COG0191	Fructose/tagatose bisphosphate aldolase	286
2904474732	349	99.72	1	346	1	352	2.0e-79	261.2	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2904474733	455	99.1	1	444	3	444	0.0e+00	607.3	COG3775	Phosphotransferase system, galactitol-specific IIC component	446
2904474734	94	98.92	2	94	2	93	1.5e-28	93.7	COG3414	Phosphotransferase system, galactitol-specific IIB component	93
2904474735	160	85.53	3	146	11	140	1.3e-26	87.3	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
2904474736	431	98.59	1	422	4	423	0.0e+00	699.6	COG4573	Tagatose-1,6-bisphosphate aldolase non-catalytic subunit AgaZ/GatZ	426
2904474737	260	99.21	1	260	1	252	2.5e-79	260.8	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2904474738	259	96.47	2	259	6	278	4.4e-59	194.5	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904474739	955	95.27	126	524	16	438	3.3e-85	281.1	COG3325	Chitinase, GH18 family	441
2904474740	176	35.09	106	166	73	112	2.0e-21	10.5	COG0607	Rhodanese-related sulfurtransferase	110
2904474740	176	96.49	1	108	3	112	2.0e-21	58.7	COG0607	Rhodanese-related sulfurtransferase	110
2904474741	105	84.75	9	105	11	110	3.1e-12	41.3	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2904474743	363	76.72	17	344	75	331	1.7e-29	97.7	COG0582	Integrase	309
2904474751	267	98.19	1	264	2	273	5.0e-81	266.2	COG0338	Site-specific DNA-adenine methylase	274
2904474756	595	98.92	1	307	1	276	5.1e-37	121.6	COG5484	Uncharacterized protein YjcR	279
2904474757	279	79.17	198	269	4	60	4.7e-04	14	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
2904474763	229	20.71	152	221	96	124	2.2e-05	10.5	COG5005	Mu-like prophage protein gpG	140
2904474763	229	34.29	6	82	22	69	2.2e-05	6.9	COG5005	Mu-like prophage protein gpG	140
2904474772	394	60.85	21	336	51	266	4.3e-12	39.9	COG3299	Uncharacterized phage protein gp47/JayE	353
2904474783	160	97.39	4	160	4	152	1.7e-66	217	COG0691	tmRNA-binding protein	153
2904474784	144	98.63	1	144	1	144	3.4e-59	193	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
2904474785	94	92.93	1	94	3	94	3.5e-43	140.5	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
2904474786	114	77.33	1	114	4	119	5.4e-43	141	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
2904474787	553	99.46	1	553	1	555	0.0e+00	697.3	COG0497	DNA repair ATPase RecN	557
2904474788	292	99.3	6	289	2	284	3.1e-94	309.6	COG0061	NAD kinase	281
2904474789	195	97.96	1	194	4	195	6.0e-61	200.1	COG0576	Molecular chaperone GrpE (heat shock protein)	193
2904474790	226	97.75	1	223	4	220	5.4e-100	328	COG0692	Uracil DNA glycosylase	223
2904474791	127	100	1	127	1	127	4.5e-80	260.6	COG3445	Autonomous glycyl radical cofactor GrcA	127
2904474792	442	81.54	1	442	27	450	0.0e+00	468.9	COG0513	Superfamily II DNA and RNA helicase	513
2904474793	248	96.77	4	248	8	247	1.4e-69	228.2	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
2904474794	511	93.85	1	511	22	509	0.0e+00	698.5	COG0029	Aspartate oxidase	518
2904474795	229	92.47	40	229	8	179	4.0e-52	170.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2904474796	215	98.12	1	210	5	213	2.3e-91	299.9	COG3073	Negative regulator of sigma E activity	213
2904474797	316	99.06	1	316	1	317	1.6e-128	422.8	COG3026	Negative regulator of sigma E activity	320
2904474798	158	98.67	1	150	1	148	1.0e-54	178.9	COG3086	Positive regulator of sigma E activity	150
2904474800	599	99	1	597	6	602	0.0e+00	1025.9	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
2904474801	325	88.07	52	313	9	163	2.5e-33	103.3	COG0681	Signal peptidase I	166
2904474803	203	86.44	1	203	27	230	4.1e-80	262.7	COG0571	dsRNA-specific ribonuclease	235
2904474804	301	99.33	3	300	2	297	6.7e-128	420.3	COG1159	GTPase Era, involved in 16S rRNA processing	298
2904474805	245	95.24	2	238	8	247	8.8e-73	239	COG1381	Recombinational DNA repair protein (RecF pathway)	251
2904474806	243	99.18	4	243	2	242	4.2e-111	364.4	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
2904474807	126	97.64	2	126	2	125	2.1e-43	141.9	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
2904474808	84	52.42	2	77	42	106	1.4e-13	45	COG1145	Ferredoxin	99
2904474809	282	98.58	1	282	3	280	9.3e-84	275.2	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2904474810	301	97.99	7	301	3	294	0.0e+00	463.7	COG2103	N-acetylmuramic acid 6-phosphate (MurNAc-6-P) etherase	298
2904474811	461	88.76	9	94	2	80	4.8e-23	74.6	COG1264	Phosphotransferase system IIB components	88
2904474811	461	92.62	109	461	7	395	2.1e-58	192.4	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
2904474812	212	89.15	3	212	5	193	2.8e-29	95.7	COG0560	Phosphoserine phosphatase	212
2904474813	185	97.39	10	160	4	152	1.3e-59	194.7	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2904474814	486	95.35	21	483	1	451	0.0e+00	689.4	COG4623	Membrane-bound lytic murein transglycosylase MltF	473
2904474815	1296	97.89	158	973	2	742	0.0e+00	959.5	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
2904474815	1296	99.18	1039	1296	2	243	6.6e-94	307.6	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
2904474819	335	86.17	8	325	41	339	8.1e-40	131.1	COG3239	Fatty acid desaturase	343
2904474820	268	70.1	43	256	85	295	7.1e-23	75.5	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
2904474821	281	95.82	1	281	10	284	9.0e-87	285.2	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2904474822	182	91.98	1	181	8	179	1.1e-29	98.3	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2904474823	263	44.62	36	154	10	67	9.1e-10	33.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2904474824	256	53.56	1	203	41	168	2.7e-27	89.6	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2904474825	306	99.01	1	303	1	300	5.8e-116	381.3	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
2904474827	192	94.85	9	192	9	192	9.1e-59	192.6	COG3963	Phospholipid N-methyltransferase	194
2904474828	174	96.51	1	173	2	167	5.2e-51	167.3	COG0703	Shikimate kinase	172
2904474830	260	99.19	2	250	2	245	6.1e-51	167	COG1414	DNA-binding transcriptional regulator, IclR family	246
2904474831	525	24.92	4	189	19	174	4.7e-47	65.2	COG1297	Uncharacterized membrane protein, oligopeptide transporter (OPT) family	624
2904474831	525	64.7	163	525	213	617	4.7e-47	88.7	COG1297	Uncharacterized membrane protein, oligopeptide transporter (OPT) family	624
2904474834	96	100	1	94	1	94	4.1e-49	159.3	COG3123	Uncharacterized conserved protein YaiE, UPF0345 family	94
2904474835	304	99.67	2	304	1	302	0.0e+00	487	COG2974	DNA recombination-dependent growth factor C	303
2904474836	306	95.16	1	305	9	303	5.8e-77	253.1	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2904474837	437	96.41	5	436	15	444	9.9e-126	414.1	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2904474838	336	94.03	3	333	11	325	1.2e-64	212.3	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2904474839	361	86.36	230	361	12	125	8.3e-28	90.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904474840	273	97.21	24	272	3	246	1.6e-67	221.9	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2904474841	254	96.51	1	254	7	255	5.6e-66	217	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2904474842	337	92.54	9	335	8	317	4.3e-36	118.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2904474843	1082	99.89	1	1080	1	948	0.0e+00	481.5	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2904474844	412	98.51	1	404	1	398	8.7e-77	253.4	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
2904474845	229	98.71	3	228	2	230	5.5e-87	285.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904474846	439	81.73	14	427	64	385	2.2e-67	222.3	COG0642	Signal transduction histidine kinase	336
2904474847	110	80.77	5	110	19	102	3.4e-21	69.5	COG2944	DNA-binding transcriptional regulator YiaG, XRE-type HTH domain	104
2904474848	131	97.56	4	131	2	121	4.9e-25	82.5	COG4737	Uncharacterized protein	123
2904474849	367	98.49	4	365	3	328	5.8e-81	266.4	COG0620	Methionine synthase II (cobalamin-independent)	330
2904474850	439	99.07	4	432	2	428	0.0e+00	534	COG1114	Branched-chain amino acid permeases	431
2904474851	474	98.05	10	470	5	457	0.0e+00	632.5	COG1113	L-asparagine transporter and related permeases	462
2904474852	583	96.33	13	575	10	534	0.0e+00	669.7	COG0405	Gamma-glutamyltranspeptidase	539
2904474853	200	98.96	1	196	2	191	1.0e-79	260.8	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
2904474854	193	100	1	193	1	193	1.5e-90	296.7	COG3124	Acyl carrier protein phosphodiesterase	193
2904474855	356	99.43	1	349	1	347	0.0e+00	499.9	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
2904474856	374	98.12	3	373	2	366	0.0e+00	605.5	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
2904474857	110	94.85	13	110	5	96	5.7e-36	116.9	COG1862	Preprotein translocase subunit YajC	97
2904474858	615	99.81	75	615	2	523	0.0e+00	655.4	COG0342	Preprotein translocase subunit SecD	506
2904474859	324	99.03	10	316	2	306	1.4e-118	389.8	COG0341	Preprotein translocase subunit SecF	305
2904474861	149	94.87	1	149	1	148	3.4e-68	222.8	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
2904474862	378	96.58	8	153	5	145	1.6e-63	206.3	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
2904474862	378	98.18	154	377	2	217	5.3e-68	222.8	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
2904474863	156	99.34	1	153	1	151	2.0e-64	210.3	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
2904474864	137	92.81	1	137	10	151	2.1e-50	165	COG0781	Transcription termination factor NusB	151
2904474865	328	100	1	322	1	320	1.4e-122	403	COG0611	Thiamine monophosphate kinase	317
2904474866	186	95.03	22	178	8	160	9.6e-59	192.5	COG1267	Phosphatidylglycerophosphatase A	160
2904474867	324	97.19	1	321	1	311	2.7e-109	359.2	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2904474868	620	99.04	6	620	2	622	0.0e+00	953.4	COG1154	Deoxyxylulose-5-phosphate synthase	627
2904474869	309	99.09	11	309	3	327	7.8e-86	280.9	COG0142	Geranylgeranyl pyrophosphate synthase	322
2904474870	80	96.3	1	80	2	79	1.3e-31	102.7	COG1722	Exonuclease VII small subunit	81
2904474871	482	67.54	390	482	20	96	1.8e-14	46.8	COG0607	Rhodanese-related sulfurtransferase	110
2904474871	482	99.48	1	384	2	383	0.0e+00	446.6	COG0301	Adenylyl- and sulfurtransferase ThiI, participates in tRNA 4-thiouridine and thiamine biosynthesis	383
2904474872	202	97.96	1	178	3	194	3.9e-31	102.7	COG0693	Putative intracellular protease/amidase	188
2904474873	303	99.03	1	296	1	306	2.1e-78	258	COG1893	Ketopantoate reductase	307
2904474875	163	98.18	1	163	4	165	4.0e-79	258.9	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
2904474876	432	60.68	1	395	3	215	1.1e-53	173.9	COG0673	Predicted dehydrogenase	342
2904474877	454	49.61	219	433	22	211	4.1e-34	24.9	COG0477	MFS family permease	338
2904474877	454	77.81	11	316	2	299	4.1e-34	88.5	COG0477	MFS family permease	338
2904474878	294	91.86	1	289	19	300	7.1e-109	358.2	COG0109	Polyprenyltransferase (heme O synthase)	304
2904474879	110	99.11	1	110	1	111	2.3e-45	147.4	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
2904474880	204	92.49	1	204	16	212	2.8e-72	236.9	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2904474881	663	99.82	38	608	2	569	0.0e+00	786.2	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2904474882	319	98.82	10	267	3	253	2.2e-86	283.3	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2904474883	492	56.92	266	490	53	270	1.7e-20	14.3	COG0477	MFS family permease	338
2904474883	492	85.9	9	325	2	330	1.7e-20	58.2	COG0477	MFS family permease	338
2904474884	192	93.63	1	192	14	204	4.1e-85	278.5	COG3056	Uncharacterized lipoprotein YajG	204
2904474885	104	95.56	1	87	3	88	3.1e-33	108.3	COG0271	Stress-induced morphogen (activity unknown)	90
2904474886	434	99.11	1	434	1	444	0.0e+00	545.4	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
2904474887	207	96	13	207	2	193	1.6e-94	309.6	COG0740	ATP-dependent protease ClpP, protease subunit	200
2904474888	424	98.53	16	423	1	403	0.0e+00	688.3	COG1219	ATP-dependent protease Clp, ATPase subunit	408
2904474890	784	98.72	2	779	4	777	0.0e+00	1190.8	COG0466	ATP-dependent Lon protease, bacterial type	782
2904474891	91	95.74	1	91	2	91	1.3e-36	119.1	COG0776	Bacterial nucleoid DNA-binding protein	94
2904474892	626	16.31	463	523	260	312	1.4e-37	4.7	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2904474892	626	93.23	8	416	6	308	1.4e-37	118.5	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2904474893	127	60.76	9	127	62	157	1.3e-28	94.6	COG1555	DNA uptake protein ComE and related DNA-binding proteins	149
2904474894	133	93.53	1	131	8	137	2.9e-39	128.6	COG0824	Acyl-CoA thioesterase FadM	137
2904474895	232	95.95	1	226	2	214	1.9e-86	283.3	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
2904474896	570	99.65	1	563	3	564	0.0e+00	537.6	COG4533	DNA-binding transcriptional regulator SgrR  of sgrS sRNA, contains a MarR-type HTH domain and a periplasmic-type solute-binding domain	564
2904474897	273	98.53	1	265	2	269	3.1e-65	215	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
2904474898	347	98.34	12	322	5	301	2.3e-81	267.3	COG0031	Cysteine synthase	300
2904474899	151	96.2	1	151	6	157	2.0e-43	142.6	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2904474900	590	99.49	1	574	3	591	0.0e+00	529	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2904474901	599	99.32	13	583	2	589	0.0e+00	517.6	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2904474903	112	100	1	112	1	112	1.3e-48	158.5	COG0347	Nitrogen regulatory protein PII	112
2904474904	429	98.3	28	429	2	406	0.0e+00	520.3	COG0004	Ammonia channel protein AmtB	409
2904474905	288	98.62	1	288	1	286	2.1e-128	421.8	COG1946	Acyl-CoA thioesterase	289
2904474906	193	95.6	1	164	1	152	1.1e-49	162.3	COG3126	Uncharacterized lipoprotein YbaY	158
2904474907	102	98.06	1	102	2	102	5.3e-45	146.2	COG3695	Alkylated DNA nucleotide flippase Atl1, participates in nucleotide excision repair, Ada-like DNA-binding domain	103
2904474909	449	99.1	13	448	3	441	3.5e-117	386.6	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
2904474910	595	98.29	3	588	9	582	0.0e+00	545.9	COG1001	Adenine deaminase	584
2904474911	318	98.01	11	308	2	296	1.1e-54	180.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904474915	253	88.58	9	242	3	227	2.2e-69	227.9	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
2904474916	285	97.46	3	281	7	275	4.1e-70	230.5	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2904474917	292	96.72	1	292	10	304	1.1e-85	281.8	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
2904474918	46	100	1	41	1	38	2.3e-22	72	COG0257	Ribosomal protein L36	38
2904474919	84	96	1	84	1	72	1.5e-28	93.2	COG0254	Ribosomal protein L31	75
2904474920	1050	99.8	1	1032	2	1013	0.0e+00	1260.5	COG0841	Multidrug efflux pump subunit AcrB	1009
2904474921	391	96.92	1	378	9	386	1.1e-78	259.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904474922	212	94.74	1	210	6	203	7.2e-30	99.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904474923	1111	98.83	206	1108	2	843	0.0e+00	956.1	COG3264	Small-conductance mechanosensitive channel	835
2904474925	178	99.43	1	176	2	176	4.7e-53	174	COG3923	Primosomal replication protein N''	175
2904474926	122	98.32	1	118	1	117	1.4e-45	148.6	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
2904474927	183	96.65	4	182	4	176	2.5e-65	213.5	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
2904474928	687	95.16	190	683	1	492	7.4e-69	222.2	COG0366	Glycosidase	505
2904474929	649	99.32	1	590	1	581	0.0e+00	607.8	COG2812	DNA polymerase III, gamma/tau subunits	515
2904474931	109	100	1	106	1	105	8.0e-46	148.9	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
2904474932	201	99.49	1	199	1	197	1.3e-83	273.6	COG0353	Recombinational DNA repair protein RecR	198
2904474933	623	99.36	3	623	1	622	0.0e+00	916.1	COG0326	Molecular chaperone, HSP90 family	623
2904474934	214	99.46	1	214	1	184	3.7e-74	243.2	COG0563	Adenylate kinase or related kinase	178
2904474935	320	98.75	1	320	2	318	5.9e-116	381.4	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
2904474936	439	99.68	40	437	2	316	7.6e-83	272.3	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2904474937	563	99.51	1	408	1	406	0.0e+00	674.6	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
2904474938	403	48.3	214	402	9	193	2.4e-23	30.6	COG0477	MFS family permease	338
2904474938	403	74.67	17	254	5	290	2.4e-23	52.6	COG0477	MFS family permease	338
2904474939	159	98.71	1	157	1	153	2.3e-55	180.8	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
2904474941	268	93.98	1	268	12	292	1.8e-85	281.1	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
2904474942	847	10.4	1	90	4	79	0.0e+00	16.6	COG2217	Cation transport ATPase	713
2904474942	847	99.45	104	841	3	729	0.0e+00	845.9	COG2217	Cation transport ATPase	713
2904474943	134	95.45	1	119	1	126	6.5e-31	101.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
2904474944	151	97.16	6	149	4	140	1.4e-45	149.4	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
2904474945	306	96.68	4	297	7	297	6.5e-92	302.2	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2904474946	285	92.79	1	285	23	305	8.0e-116	381.3	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2904474947	258	94.72	1	257	6	256	1.0e-51	169.8	COG0300	Short-chain dehydrogenase	265
2904474948	195	97.74	6	195	2	217	4.7e-43	142.1	COG2755	Lysophospholipase L1 or related esterase	216
2904474949	228	99.56	1	228	1	227	3.3e-112	367.9	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
2904474950	814	99.28	2	812	6	828	0.0e+00	1080.4	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
2904474951	354	97.87	1	350	1	368	8.5e-121	393.2	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
2904474952	169	96.34	4	169	5	162	8.1e-74	240.9	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
2904474954	210	100	1	203	1	203	7.4e-89	291.2	COG4445	tRNA isopentenyl-2-thiomethyl-A-37 hydroxylase MiaE (synthesis of 2-methylthio-cis-ribozeatin)	203
2904474955	240	99.17	4	240	1	239	1.8e-84	277.2	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
2904474956	164	98.73	1	164	2	156	9.0e-55	179.4	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
2904474957	463	99.78	1	463	1	464	0.0e+00	631	COG0215	Cysteinyl-tRNA synthetase	464
2904474958	290	94.81	12	288	1	274	1.4e-65	215.8	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
2904474959	727	88.1	1	274	37	310	3.1e-37	122.5	COG3447	Integral membrane sensor domain MASE1	308
2904474959	727	96.17	518	699	5	180	2.6e-50	164.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904474960	479	96.04	37	479	15	450	0.0e+00	480.1	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
2904474962	734	65.57	302	486	5	124	3.6e-07	23.7	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904474962	734	94.94	484	733	6	249	3.5e-69	226.4	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2904474963	514	99.6	11	498	2	494	0.0e+00	575.3	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
2904474964	689	98.86	1	689	7	697	0.0e+00	916.1	COG0855	Polyphosphate kinase	696
2904474966	191	91.44	2	172	13	183	5.4e-41	135	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2904474967	212	99	2	201	1	198	1.0e-81	267.6	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
2904474968	345	97.97	4	345	2	339	0.0e+00	513	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
2904474969	208	99.52	1	208	2	210	3.2e-92	302.3	COG0035	Uracil phosphoribosyltransferase	210
2904474970	430	94.96	2	425	11	443	0.0e+00	433.8	COG2233	Xanthine/uracil permease	451
2904474971	238	56.12	3	238	91	333	3.2e-59	195.3	COG0593	Chromosomal replication initiation ATPase DnaA	408
2904474972	118	96.58	3	118	3	115	3.0e-38	124.9	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2904474973	512	95.05	3	511	25	485	0.0e+00	600.4	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2904474974	354	96.67	4	353	2	349	1.4e-93	308.1	COG0628	Predicted PurR-regulated permease PerM	355
2904474975	155	96.82	1	154	2	153	6.3e-64	208.7	COG1225	Peroxiredoxin	157
2904474976	188	98.86	4	179	2	175	1.1e-76	250.7	COG2716	Glycine cleavage system regulatory protein	176
2904474977	293	97.66	1	293	4	295	2.6e-114	375.4	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2904474978	359	100	16	354	1	343	1.8e-118	390	COG3317	Uncharacterized lipoprotein	342
2904474979	237	94.18	1	237	6	264	1.6e-80	264.5	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
2904474980	290	98.31	1	290	1	291	1.1e-130	429.6	COG2321	Predicted metalloprotease	295
2904474981	150	96.03	3	150	3	147	2.7e-61	200.1	COG2707	Uncharacterized membrane protein, DUF441 family	151
2904474982	661	93.61	2	659	24	741	0.0e+00	563.6	COG1444	tRNA(Met) C34 N-acetyltransferase TmcA	758
2904474983	216	95.22	1	211	8	206	1.3e-44	146.5	COG0400	Predicted esterase	207
2904474984	366	98.92	1	365	4	369	2.2e-111	366.5	COG1932	Phosphoserine aminotransferase	365
2904474987	224	86.78	1	210	27	236	2.6e-43	142.7	COG1876	LD-carboxypeptidase LdcB, LAS superfamily	241
2904474988	375	96.17	1	375	14	415	4.9e-106	349.7	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2904474989	127	96.58	8	125	4	116	1.2e-34	113.4	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2904474990	1051	99.8	1	1030	2	1013	0.0e+00	1252.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2904474991	96	96.84	3	96	2	93	3.5e-44	143.2	COG4519	Uncharacterized protein	95
2904474992	196	90.7	40	196	11	166	5.0e-20	66.4	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2904474994	355	23.76	4	106	24	66	1.2e-07	10	COG5342	Invasion protein IalB, involved in pathogenesis	181
2904474994	355	23.76	113	164	137	179	1.2e-07	14.4	COG5342	Invasion protein IalB, involved in pathogenesis	181
2904474995	72	94.52	1	72	2	70	1.3e-29	96.1	COG2501	Ribosome-associated protein YbcJ, S4-like RNA binding protein	73
2904474996	290	98.94	4	286	1	281	3.6e-123	404.3	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
2904474997	303	97.14	3	303	2	307	2.0e-78	258	COG0039	Malate/lactate dehydrogenase	313
2904474999	215	74.57	1	161	42	214	1.2e-11	36.7	COG0671	Membrane-associated phospholipid phosphatase	232
2904475000	552	97.14	1	552	12	555	4.9e-112	369.9	COG2831	Hemolysin activation/secretion protein	554
2904475001	1518	86.58	57	951	38	953	1.2e-22	74.5	COG3210	Large exoprotein involved in heme utilization or adhesion	1013
2904475004	237	98.68	10	237	3	227	4.5e-50	164.5	COG5587	Uncharacterized conserved protein, DUF2461 family	228
2904475007	471	51.7	251	465	6	203	2.4e-35	21.6	COG0477	MFS family permease	338
2904475007	471	85.12	19	316	4	329	2.4e-35	106	COG0477	MFS family permease	338
2904475008	184	88.42	12	184	10	177	8.5e-48	156.9	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2904475009	135	96.18	1	129	5	130	4.2e-32	105.1	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2904475010	322	96.17	135	311	5	180	5.7e-39	128	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904475012	173	81.99	9	169	27	158	7.7e-41	133.5	COG3837	Uncharacterized conserved protein, cupin superfamily	161
2904475015	699	99.41	9	693	3	674	0.0e+00	730.2	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
2904475016	376	92.59	1	346	25	324	6.6e-49	161.3	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2904475017	247	99.58	1	247	1	236	8.8e-56	183.9	COG3416	Uncharacterized protein	233
2904475019	69	97.01	3	69	2	66	3.8e-37	120.6	COG1278	Cold shock protein, CspA family	67
2904475020	395	48.56	212	394	4	189	8.0e-36	21.3	COG0477	MFS family permease	338
2904475020	395	68.93	7	234	8	271	8.0e-36	101.2	COG0477	MFS family permease	338
2904475021	218	67.46	7	215	6	146	4.1e-21	70.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904475022	127	97.62	1	125	2	124	7.5e-37	120.5	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
2904475024	140	72.22	5	139	40	156	4.6e-13	44.1	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904475025	448	94.08	21	445	12	440	7.8e-57	187.1	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2904475027	264	95.32	1	263	3	267	3.6e-63	207.4	COG0388	Predicted amidohydrolase	274
2904475028	302	94.35	1	295	10	276	2.5e-33	110	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904475029	327	94.3	37	294	12	226	5.9e-72	236.2	COG0765	ABC-type amino acid transport system, permease component	222
2904475030	265	98.76	15	265	3	241	8.9e-111	363.1	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2904475031	68	69.15	1	68	1	65	1.8e-19	64.4	COG1826	Sec-independent protein translocase protein TatA	94
2904475032	321	98.69	13	321	2	303	0.0e+00	488.7	COG0320	Lipoate synthase	306
2904475033	227	93.78	1	221	6	216	7.2e-85	278.1	COG0321	Lipoate-protein ligase B	221
2904475034	87	98.89	1	87	2	90	1.1e-43	142	COG2921	Putative lipoic acid-binding regulatory protein	90
2904475035	402	96.18	3	401	16	393	0.0e+00	451.9	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2904475036	383	88.71	3	247	13	232	6.1e-61	200.1	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
2904475037	370	97.12	2	370	6	376	1.6e-127	419.6	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
2904475038	634	98.26	7	622	6	626	0.0e+00	575.8	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2904475039	156	99.36	1	155	2	156	8.0e-61	199.1	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
2904475040	105	88.7	2	105	4	105	2.4e-42	137.6	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
2904475041	225	98.49	12	225	3	198	5.1e-65	213.4	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
2904475042	318	91.62	1	307	27	332	1.9e-94	311	COG1466	DNA polymerase III, delta subunit	334
2904475043	155	65.19	1	141	56	173	5.0e-44	144.4	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
2904475044	860	100	1	859	1	823	0.0e+00	1142.9	COG0495	Leucyl-tRNA synthetase	814
2904475045	166	57.63	1	163	68	169	4.6e-04	14.7	COG1592	Rubrerythrin	166
2904475046	241	99.17	1	240	2	241	3.3e-114	374.3	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2904475047	225	90.79	3	225	18	224	1.3e-67	222	COG0765	ABC-type amino acid transport system, permease component	222
2904475048	246	93.42	3	241	13	225	1.7e-65	215.2	COG0765	ABC-type amino acid transport system, permease component	222
2904475049	298	97.88	1	279	3	279	1.4e-57	189.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904475050	509	97.69	1	509	8	515	0.0e+00	549.3	COG0815	Apolipoprotein N-acyltransferase	518
2904475051	292	99.32	1	292	1	291	0.0e+00	506.5	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
2904475052	157	98.05	4	153	3	153	2.7e-54	177.3	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
2904475053	352	96.18	1	335	11	337	0.0e+00	487.6	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
2904475054	461	96.83	1	429	14	440	0.0e+00	513.8	COG0621	tRNA A37 methylthiotransferase MiaB	437
2904475055	394	98.98	6	394	2	390	2.9e-108	357.1	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2904475062	554	99.82	1	553	1	547	0.0e+00	630.9	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2904475063	250	94.44	1	250	9	263	1.0e-78	258.8	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
2904475064	407	97.42	82	404	4	305	6.6e-66	216.7	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2904475065	380	99.21	2	380	1	378	0.0e+00	483.5	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
2904475066	266	100	1	249	1	240	3.2e-80	263.3	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
2904475067	679	92.13	421	505	3	84	5.8e-24	77	COG1264	Phosphotransferase system IIB components	88
2904475067	679	95.48	1	410	4	404	2.9e-118	389.6	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
2904475067	679	96.79	524	678	4	154	3.6e-57	186.3	COG2190	Phosphotransferase system IIA component	156
2904475068	556	99.58	20	529	3	480	0.0e+00	512.3	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2904475070	113	51.9	1	78	4	44	1.5e-03	12.2	COG4238	Outer membrane murein-binding lipoprotein Lpp	78
2904475071	151	91.72	1	142	7	139	1.6e-53	174.7	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2904475072	175	99.35	1	168	1	152	1.6e-54	178.7	COG0716	Flavodoxin	151
2904475073	554	87.76	88	516	53	425	8.1e-109	359.2	COG0840	Methyl-accepting chemotaxis protein	408
2904475075	256	94.24	1	256	16	293	5.1e-39	128.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904475076	184	100	1	184	1	181	5.0e-90	294.5	COG3057	Negative regulator of replication initiation	181
2904475077	547	99.81	25	547	1	523	0.0e+00	824.3	COG0033	Phosphoglucomutase	524
2904475078	238	72.26	74	221	4	102	3.7e-27	88.6	COG1695	DNA-binding transcriptional regulator, PadR family	138
2904475079	229	98.28	6	229	2	229	1.6e-76	251	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904475080	898	99.44	1	891	3	894	0.0e+00	1173.4	COG2205	K+-sensing histidine kinase KdpD	890
2904475081	197	99.47	5	194	2	189	4.1e-75	246	COG2156	K+-transporting ATPase, c chain	190
2904475082	688	99.56	2	688	2	680	0.0e+00	1137.7	COG2216	High-affinity K+ transport system, ATPase chain B	681
2904475083	562	99.29	2	558	4	559	0.0e+00	838.5	COG2060	K+-transporting ATPase, A chain	560
2904475086	317	96.79	2	155	5	155	1.8e-45	148.4	COG1683	Uncharacterized conserved protein YbbK, DUF523 family	156
2904475086	317	98.16	156	317	1	160	1.4e-71	233.7	COG3272	Uncharacterized conserved protein YbgA, DUF1722 family	163
2904475087	476	99.78	1	472	2	463	0.0e+00	597.9	COG0415	Deoxyribodipyrimidine photolyase	461
2904475088	327	89.89	4	326	35	354	3.3e-99	326.4	COG5212	cAMP phosphodiesterase	356
2904475089	247	99.61	1	247	1	253	2.6e-74	244	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
2904475090	478	48.04	192	419	8	191	3.5e-24	47.6	COG0477	MFS family permease	338
2904475090	478	49.61	3	204	3	192	3.5e-24	38	COG0477	MFS family permease	338
2904475091	221	94.27	6	221	2	215	3.2e-81	266.3	COG2049	Allophanate hydrolase subunit 1	223
2904475092	309	98.73	2	308	1	312	1.2e-128	422.9	COG1984	Allophanate hydrolase subunit 2	314
2904475093	245	98.41	1	245	3	250	2.5e-108	355.5	COG1540	Lactam utilization protein B (function unknown)	252
2904475094	216	99.52	2	209	2	207	2.5e-89	292.9	COG2039	Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)	207
2904475095	264	99.64	1	264	1	273	2.9e-63	208.5	COG0266	Formamidopyrimidine-DNA glycosylase	273
2904475096	938	89.21	352	938	72	658	2.1e-37	123.6	COG3468	Type V secretory pathway, adhesin AidA	644
2904475097	427	98.23	27	427	4	392	0.0e+00	547.3	COG0372	Citrate synthase	390
2904475098	125	96.24	3	125	1	128	8.0e-35	114.4	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
2904475099	115	97.44	1	115	2	115	7.7e-39	126.5	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
2904475100	588	98.59	1	577	3	560	0.0e+00	785.9	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2904475101	238	98.72	1	238	1	232	1.1e-90	297.2	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
2904475102	935	99.89	6	934	1	922	0.0e+00	1477.5	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
2904475103	409	99.31	2	408	3	433	0.0e+00	511	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2904475104	388	99.74	1	388	1	382	0.0e+00	558	COG0045	Succinyl-CoA synthetase, beta subunit	387
2904475105	290	98.64	1	290	1	290	0.0e+00	448	COG0074	Succinyl-CoA synthetase, alpha subunit	293
2904475106	522	99.12	1	519	1	452	0.0e+00	658.8	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
2904475107	379	99.71	1	374	1	344	1.6e-128	423.3	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
2904475108	37	97.3	1	37	1	36	3.3e-22	72.7	COG4890	Predicted outer membrane lipoprotein	37
2904475109	97	98.97	1	97	1	96	1.1e-41	135.8	COG3790	Predicted membrane protein, encoded in cydAB operon	97
2904475110	134	94.24	1	134	4	134	7.7e-49	159.7	COG0824	Acyl-CoA thioesterase FadM	137
2904475111	229	99.54	9	224	1	215	5.5e-77	253	COG0811	Biopolymer transport protein ExbB/TolQ	216
2904475112	143	97.84	1	143	1	136	2.9e-40	131.9	COG0848	Biopolymer transport protein ExbD	137
2904475113	403	99.48	3	402	3	388	1.9e-116	379.9	COG3064	Membrane protein involved in colicin uptake	387
2904475114	430	99.07	5	430	5	429	0.0e+00	518.1	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2904475115	170	90.95	1	170	15	195	6.1e-49	161.3	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2904475117	263	99.24	1	263	1	262	1.4e-81	268.7	COG1729	Periplasmic TolA-binding protein (function unknown)	262
2904475123	354	95.69	5	343	14	324	7.8e-124	407.1	COG0379	Quinolinate synthase	324
2904475124	242	97.75	1	241	4	220	9.4e-85	278	COG3201	Nicotinamide riboside transporter PnuC	222
2904475125	317	94.31	2	288	18	299	8.3e-111	364.1	COG1230	Co/Zn/Cd efflux system component	296
2904475126	109	30.92	1	92	3	79	4.8e-04	14.1	COG1651	Protein-disulfide isomerase	244
2904475127	350	99.43	1	350	2	350	0.0e+00	574	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
2904475128	157	56.17	9	142	66	156	1.1e-08	30	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904475129	107	15.86	2	85	331	402	7.0e-03	9.2	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
2904475132	250	99.13	3	232	2	229	5.4e-106	347.8	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
2904475134	348	97.76	5	347	5	310	2.5e-87	287.3	COG2017	Galactose mutarotase or related enzyme	308
2904475135	382	98.73	1	382	5	392	0.0e+00	515.5	COG0153	Galactokinase	390
2904475136	349	99.71	9	346	1	340	0.0e+00	496.8	COG1085	Galactose-1-phosphate uridylyltransferase	338
2904475137	338	99.7	1	336	1	328	0.0e+00	468	COG1087	UDP-glucose 4-epimerase	329
2904475138	315	98.01	7	298	2	296	1.3e-58	193.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475140	489	82.1	2	218	38	248	4.0e-127	100.7	COG1119	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA	257
2904475140	489	98.83	230	486	2	255	4.0e-127	310.4	COG1119	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA	257
2904475141	260	91.3	122	191	3	65	1.1e-21	37.7	COG3585	Molybdopterin-binding protein	69
2904475141	260	91.3	193	259	6	68	1.1e-21	31.7	COG3585	Molybdopterin-binding protein	69
2904475141	260	100	1	130	1	131	2.9e-48	157.1	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
2904475143	257	94.01	4	257	15	265	4.5e-78	256.4	COG0725	ABC-type molybdate transport system, periplasmic component	258
2904475144	229	98.67	3	228	2	223	1.1e-97	320.1	COG4149	ABC-type molybdate transport system, permease component	225
2904475145	353	99.72	1	353	1	351	0.0e+00	541.7	COG4148	ABC-type molybdate transport system, ATPase component	352
2904475146	87	51.54	1	85	2	68	7.4e-14	47.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2904475147	89	86.59	1	78	5	75	6.1e-36	116.4	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
2904475148	273	99.26	1	273	1	270	2.2e-71	235.2	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
2904475149	332	99.71	1	330	1	345	1.2e-107	354.4	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
2904475150	503	81.88	38	498	78	425	2.0e-111	367.5	COG0840	Methyl-accepting chemotaxis protein	408
2904475151	426	96.79	2	424	7	398	1.7e-101	334.3	COG4677	Pectin methylesterase and related acyl-CoA thioesterases	405
2904475152	160	86.03	1	160	24	177	4.2e-57	187	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
2904475153	231	93.88	14	230	10	193	3.7e-47	154.9	COG0693	Putative intracellular protease/amidase	188
2904475154	345	98.53	1	344	5	339	0.0e+00	499.6	COG2130	NADPH-dependent curcumin reductase CurA	340
2904475155	237	100	1	237	1	237	6.8e-119	390	COG3700	Acid phosphatase (class B)	237
2904475156	259	96.47	1	259	4	276	3.9e-56	184.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904475157	380	95.45	3	380	13	390	2.2e-102	337.3	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2904475158	317	98.34	13	302	2	297	1.2e-56	187	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475159	425	97.99	1	425	4	441	0.0e+00	577	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2904475160	345	93.79	1	328	12	328	0.0e+00	457.7	COG0502	Biotin synthase or related enzyme	335
2904475161	383	98.97	1	381	2	387	9.9e-129	423.6	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
2904475162	263	61.51	2	209	9	155	1.1e-26	87.6	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2904475163	226	99.1	1	226	1	221	1.9e-81	267.3	COG0132	Dethiobiotin synthetase	223
2904475164	236	98.73	1	236	3	236	5.3e-74	242.7	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2904475165	668	99.4	1	668	2	660	0.0e+00	1122.8	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
2904475166	122	50	1	108	10	77	2.9e-34	112.7	COG4628	Uncharacterized conserved protein, DUF2132 family	136
2904475167	174	85.44	2	155	5	180	4.2e-24	78.6	COG1335	Nicotinamidase-related amidase	205
2904475168	302	95.33	3	302	3	308	3.3e-87	286.8	COG0391	Archaeal 2-phospho-L-lactate transferase/Bacterial gluconeogenesis factor, CofD/UPF0052 family	323
2904475170	328	100	3	328	1	325	3.1e-117	385.4	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
2904475171	170	95.88	3	170	6	168	5.5e-57	186.2	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
2904475172	163	99.36	1	158	1	155	1.8e-70	230.1	COG0315	Molybdenum cofactor biosynthesis enzyme	157
2904475173	81	100	1	81	1	84	5.0e-25	82.5	COG1977	Molybdopterin converting factor, small subunit	84
2904475174	150	97.99	1	149	2	147	2.7e-57	187.1	COG0314	Molybdopterin synthase catalytic subunit	149
2904475175	236	99.57	1	236	1	231	1.0e-73	242	COG0670	Integral membrane protein, interacts with FtsH	233
2904475176	400	51.96	204	399	4	202	7.0e-52	73.3	COG0477	MFS family permease	338
2904475176	400	54.57	4	218	4	212	7.0e-52	101.8	COG0477	MFS family permease	338
2904475177	470	84.62	1	470	29	468	0.0e+00	509.7	COG0513	Superfamily II DNA and RNA helicase	513
2904475178	215	93.15	6	215	9	212	1.1e-56	186.6	COG2345	Predicted transcriptional regulator, ArsR family	218
2904475179	481	52.22	263	476	8	207	3.4e-34	25.9	COG0477	MFS family permease	338
2904475179	481	82.77	13	323	6	322	3.4e-34	90.7	COG0477	MFS family permease	338
2904475180	310	93.23	1	309	10	312	7.0e-91	299	COG0042	tRNA-dihydrouridine synthase	323
2904475181	310	76.34	1	309	7	306	7.4e-85	279.7	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2904475183	219	12.67	27	197	672	819	7.0e-11	34.2	COG1196	Chromosome segregation ATPase	1163
2904475184	196	19.87	26	89	171	232	4.2e-01	5.4	COG0501	Zn-dependent protease with chaperone function	302
2904475184	196	20.83	110	196	23	87	4.2e-01	3.8	COG0501	Zn-dependent protease with chaperone function	302
2904475185	563	99.36	9	557	2	467	3.2e-52	172.2	COG0277	FAD/FMN-containing dehydrogenase	459
2904475186	278	96.12	22	278	2	249	6.0e-99	324.7	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
2904475187	310	96.01	1	310	11	299	1.5e-84	278.2	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
2904475188	287	93.31	1	284	19	283	1.7e-81	267.9	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
2904475189	307	91.2	6	284	25	283	9.7e-76	248.9	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
2904475190	373	97.66	1	373	9	384	0.0e+00	461.7	COG2850	Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain	383
2904475191	459	95.2	1	459	19	474	0.0e+00	478	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2904475192	109	40.46	15	96	43	95	1.6e-05	19.1	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2904475193	365	99.37	2	351	2	317	2.1e-120	395.9	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
2904475194	113	95.6	16	113	2	88	2.8e-25	82.6	COG5606	Predicted DNA-binding protein, XRE-type HTH domain	91
2904475195	119	93.1	1	114	7	114	6.6e-37	120.6	COG4679	Phage-related protein	116
2904475197	85	18.65	1	77	6	66	8.6e-04	12.6	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2904475198	85	19.27	1	79	6	68	3.1e-04	14.1	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2904475201	219	81.34	9	211	13	182	1.1e-20	69.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904475202	279	93.33	1	279	11	290	8.2e-85	279.1	COG3662	Uncharacterized conserved protein, DUF2236 family	300
2904475203	507	98.26	1	507	7	513	0.0e+00	646.8	COG2978	p-Aminobenzoyl-glutamate transporter AbgT	516
2904475204	488	98.73	12	463	4	391	2.1e-107	353.8	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2904475205	438	98.98	2	435	3	391	5.3e-112	369	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2904475206	298	97.67	5	298	2	295	1.5e-58	193.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475208	498	49.87	292	485	2	192	2.9e-29	12	COG0477	MFS family permease	338
2904475208	498	54.57	48	294	6	214	2.9e-29	90.6	COG0477	MFS family permease	338
2904475209	312	95.67	3	307	14	300	1.8e-105	346.6	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
2904475210	389	95.07	155	389	5	216	4.1e-76	249.8	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
2904475211	314	99.04	1	310	1	311	1.6e-129	426	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
2904475212	252	95.52	24	248	8	220	4.1e-70	230.1	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
2904475213	58	20.23	2	53	72	106	2.8e-03	12.1	COG1495	Disulfide bond formation protein DsbB	170
2904475214	305	96.35	5	298	8	297	1.0e-43	143.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2904475218	410	97.55	122	408	7	285	3.6e-98	322.4	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2904475219	238	92.72	1	238	6	247	1.9e-71	234.4	COG3496	Uncharacterized conserved protein, DUF1365 family	261
2904475220	452	94.85	1	451	9	432	0.0e+00	469.7	COG2907	Predicted NAD/FAD-binding protein	447
2904475221	238	77.61	1	226	7	214	7.3e-39	128.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904475223	286	76.52	4	153	1	101	1.4e-24	77.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
2904475224	189	83.85	11	154	2	110	1.7e-17	58.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2904475225	179	68.78	10	178	53	182	1.6e-13	45.4	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2904475226	336	96.24	18	336	6	312	6.4e-79	259.4	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2904475227	500	98.4	1	497	6	498	0.0e+00	551.7	COG1129	ABC-type sugar transport system, ATPase component	500
2904475229	369	33.16	246	365	110	173	6.9e-36	20.4	COG4950	N-terminal domain of uncharacterized protein YciW (function unknown)	193
2904475229	369	86.01	2	165	18	183	6.9e-36	96.3	COG4950	N-terminal domain of uncharacterized protein YciW (function unknown)	193
2904475230	353	94.75	7	328	17	341	2.6e-45	149	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2904475231	539	98.73	8	538	4	548	0.0e+00	642.6	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2904475232	287	89.26	7	287	25	290	5.9e-79	259.4	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904475233	319	99.37	1	310	1	316	3.5e-87	287.1	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904475234	546	97.06	1	545	10	570	3.4e-85	281.3	COG0747	ABC-type transport system, periplasmic component	556
2904475235	448	96.27	12	442	9	447	7.2e-119	391.3	COG2233	Xanthine/uracil permease	451
2904475236	201	90.27	23	200	6	172	2.1e-48	158.6	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2904475237	196	93.98	7	194	4	206	3.8e-31	102.8	COG0778	Nitroreductase	207
2904475238	279	91.86	2	259	23	293	3.6e-34	113	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904475239	128	88.24	3	128	15	134	1.0e-30	100.8	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2904475240	250	98.06	33	244	1	202	3.6e-55	181.3	COG1335	Nicotinamidase-related amidase	205
2904475241	363	98.54	6	356	3	340	1.2e-74	245.7	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2904475242	229	85.17	18	227	7	184	6.0e-28	93.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904475243	329	78.68	1	178	1	155	8.9e-15	49.2	COG1988	Membrane-bound metal-dependent hydrolase YbcI, DUF457 family	190
2904475244	1576	94.01	1156	1574	9	432	4.4e-80	263.1	COG5368	Uncharacterized protein	451
2904475245	464	96.54	10	464	6	451	0.0e+00	638.3	COG1113	L-asparagine transporter and related permeases	462
2904475249	556	97.09	29	466	1	401	1.6e-123	407	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2904475250	252	78.79	125	252	22	125	2.4e-25	83	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904475251	57	51.92	1	57	3	56	9.0e-03	11.3	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2904475253	228	99.53	12	220	1	210	4.6e-65	213.5	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2904475254	611	99.5	4	609	4	598	0.0e+00	789.4	COG0322	Excinuclease UvrABC, nuclease subunit	581
2904475255	182	92.78	1	182	11	190	8.1e-52	170.6	COG0558	Phosphatidylglycerophosphate synthase	192
2904475259	88	62.32	5	68	14	56	2.3e-04	15.4	COG3529	Predicted nucleic-acid-binding protein, contains Zn-ribbon domain	66
2904475261	254	97.64	3	254	3	250	4.6e-69	227.1	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2904475262	158	93.51	2	153	5	148	3.5e-33	108.6	COG3449	DNA gyrase inhibitor GyrI	154
2904475270	148	93.71	1	144	6	154	9.2e-19	63.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2904475271	264	97.56	16	254	1	240	1.3e-50	166	COG1414	DNA-binding transcriptional regulator, IclR family	246
2904475272	533	95.04	19	526	5	368	6.1e-18	47.8	COG0477	MFS family permease	338
2904475273	344	91.76	3	344	18	340	2.7e-101	332.9	COG1566	Multidrug resistance efflux pump	352
2904475274	394	86.89	1	375	18	355	2.2e-08	27.5	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2904475275	522	95.51	3	522	20	530	0.0e+00	787.2	COG3131	Periplasmic glucans biosynthesis protein	534
2904475276	856	99.59	64	838	3	735	0.0e+00	1223.1	COG2943	Membrane glycosyltransferase	736
2904475277	81	93.75	7	81	4	78	6.5e-23	75.1	COG5645	Uncharacterized conserved protein YceK	80
2904475281	412	48.56	212	409	4	189	2.3e-47	58.5	COG0477	MFS family permease	338
2904475281	412	51.7	16	221	2	199	2.3e-47	104.4	COG0477	MFS family permease	338
2904475282	144	86.11	6	142	12	135	1.9e-18	61.5	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2904475283	311	99.03	2	307	4	308	6.9e-118	387.6	COG1560	Lauroyl/myristoyl acyltransferase	308
2904475284	365	93.39	1	357	3	341	6.0e-115	378.6	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2904475285	351	98.7	20	339	2	305	5.0e-111	365	COG1054	Predicted sulfurtransferase	308
2904475286	192	99.48	2	192	2	193	1.8e-65	214.5	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
2904475287	181	98.9	3	181	1	179	1.5e-58	191.8	COG3038	Cytochrome b561	181
2904475288	380	93.08	3	371	27	389	1.6e-55	183	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904475289	1031	99.7	1	1024	3	1013	0.0e+00	1089.6	COG0841	Multidrug efflux pump subunit AcrB	1009
2904475290	347	95	2	344	10	351	1.0e-78	259.1	COG0628	Predicted PurR-regulated permease PerM	355
2904475293	222	32.7	1	95	1	69	4.2e-15	10.3	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2904475293	222	32.7	95	194	135	203	4.2e-15	38.2	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2904475294	371	97.16	1	371	3	379	1.7e-51	170.1	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2904475297	349	99.13	4	347	3	343	0.0e+00	542.3	COG0418	Dihydroorotase	344
2904475299	95	91.92	1	95	3	93	1.8e-26	86.5	COG1359	Quinol monooxygenase YgiN	100
2904475300	1091	99.39	1	490	4	489	0.0e+00	683.9	COG1530	Ribonuclease G or E	487
2904475302	320	98.63	7	304	4	291	8.2e-87	285.6	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2904475303	197	98.45	4	197	2	192	2.0e-61	201	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
2904475304	174	99.44	1	173	1	178	2.7e-54	178.3	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
2904475305	55	96.49	1	55	1	55	8.7e-26	84.4	COG0333	Ribosomal protein L32	57
2904475306	344	98.53	3	344	2	335	0.0e+00	446	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
2904475307	304	95.09	1	304	16	325	1.6e-128	422.6	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2904475308	309	98.24	1	309	2	335	8.3e-97	318.6	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
2904475309	244	99.63	1	243	1	267	7.1e-80	262.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904475310	78	96.3	1	78	3	80	1.5e-30	99.6	COG0236	Acyl carrier protein	80
2904475311	413	99.28	2	413	2	412	0.0e+00	548.9	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2904475312	265	91.93	1	264	14	275	2.5e-55	182.7	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2904475313	341	97.09	1	337	8	341	2.1e-122	402.9	COG1559	Cell division protein YceG, involved in septum cleavage	342
2904475314	216	99.52	1	209	1	207	8.3e-70	229.1	COG0125	Thymidylate kinase	208
2904475315	339	48.89	11	332	32	317	1.1e-29	98.2	COG2812	DNA polymerase III, gamma/tau subunits	515
2904475316	266	99.22	1	258	2	256	8.9e-91	298.1	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
2904475317	477	87.64	399	477	3	80	7.4e-28	90.4	COG1264	Phosphotransferase system IIB components	88
2904475317	477	97.86	1	403	2	412	0.0e+00	434.2	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
2904475318	117	74.47	3	114	2	106	3.9e-34	111.9	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2904475319	122	96.75	1	122	5	123	1.2e-33	110.3	COG5633	Uncharacterized conserved protein YcfL	123
2904475320	196	97.5	1	196	4	198	4.4e-50	164.5	COG3417	Outer membrane lipoprotein LpoB, binds and activates PBP1b	200
2904475321	285	93.62	23	284	6	269	2.6e-32	106.7	COG0510	Thiamine kinase and related kinases	269
2904475322	347	76.02	3	347	7	323	2.5e-96	317.7	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2904475323	180	96.91	1	180	4	191	1.7e-73	241.1	COG3150	Predicted esterase YcpF, UPF0227 family	191
2904475324	434	98.78	3	423	2	406	0.0e+00	484.6	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2904475325	178	97.77	1	178	1	175	8.4e-92	300.5	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
2904475326	1147	98.95	7	1147	9	1136	0.0e+00	1557	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
2904475327	400	100	1	400	1	410	0.0e+00	448.8	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2904475328	234	98.23	6	230	2	223	3.6e-89	292.2	COG1136	ABC-type lipoprotein export system, ATPase component	226
2904475329	416	99.02	4	415	4	409	0.0e+00	471.5	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2904475330	275	98.05	27	272	3	254	7.9e-76	248.8	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
2904475331	409	99.04	1	407	4	415	0.0e+00	479.5	COG2195	Di- or tripeptidase	414
2904475333	212	12.21	25	212	684	778	4.8e-11	36.4	COG5295	Autotransporter adhesin	715
2904475337	160	98.1	1	160	1	155	9.8e-42	136.9	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2904475341	75	14.63	6	61	280	328	4.5e-09	29.8	COG0582	Integrase	309
2904475342	199	98.12	1	199	3	211	1.9e-52	172.7	COG0655	Multimeric flavodoxin WrbA	207
2904475343	62	40	16	60	44	75	1.8e-06	22.5	COG5302	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid	80
2904475345	701	99.31	1	701	1	724	0.0e+00	975	COG0480	Translation elongation factor EF-G, a GTPase	697
2904475346	117	77.97	1	106	13	104	1.6e-10	35.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2904475347	303	98.34	2	303	2	297	1.4e-66	219.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475348	185	85.28	8	184	6	173	1.0e-36	120.9	COG2059	Chromate transport protein ChrA	195
2904475349	172	87.31	1	172	5	176	1.2e-33	110.9	COG2059	Chromate transport protein ChrA	195
2904475350	653	89.21	74	568	1	372	1.4e-62	203.3	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2904475351	227	96.36	6	227	8	219	1.3e-58	192.2	COG4122	Predicted O-methyltransferase YrrM	219
2904475352	703	97.36	1	703	22	795	1.5e-105	349	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904475353	196	90.91	1	196	14	203	1.9e-21	72.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904475354	374	94.6	4	373	8	340	2.5e-93	306.6	COG1566	Multidrug resistance efflux pump	352
2904475355	517	42.04	273	515	8	168	8.8e-31	18.4	COG0477	MFS family permease	338
2904475355	517	75.2	19	311	4	291	8.8e-31	88.6	COG0477	MFS family permease	338
2904475356	282	89.26	1	213	27	242	6.0e-60	197.2	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2904475357	476	10.08	412	476	437	485	0.0e+00	40.9	COG1785	Alkaline phosphatase	482
2904475357	476	79.22	11	434	12	396	0.0e+00	438.3	COG1785	Alkaline phosphatase	482
2904475358	303	94.43	3	300	7	294	1.7e-87	287.7	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2904475359	396	92.33	42	396	15	339	4.2e-102	335.6	COG1566	Multidrug resistance efflux pump	352
2904475360	522	38.64	267	516	11	158	4.2e-45	14.8	COG0477	MFS family permease	338
2904475360	522	71.28	11	277	6	278	4.2e-45	140.1	COG0477	MFS family permease	338
2904475361	554	98.04	44	529	2	452	3.1e-124	409.5	COG1538	Outer membrane protein TolC	457
2904475362	302	78.03	159	289	25	127	2.2e-25	82.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904475363	277	96.27	1	258	3	260	1.7e-53	176.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904475364	335	96.04	14	335	14	328	3.5e-78	256.9	COG0598	Mg2+ and Co2+ transporter CorA	322
2904475366	111	91.67	1	108	6	104	4.3e-12	40.7	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
2904475367	417	87.83	5	414	40	443	3.7e-23	75.7	COG1538	Outer membrane protein TolC	457
2904475368	414	15.13	4	155	38	96	8.1e-32	19.8	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904475368	414	58.46	157	405	149	376	8.1e-32	91	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904475369	1043	99.71	1	1043	1	1027	0.0e+00	1402.2	COG3696	Cu/Ag efflux pump CusA	1027
2904475370	808	90.96	11	807	51	825	9.3e-128	421.6	COG3264	Small-conductance mechanosensitive channel	835
2904475372	553	99.63	1	551	1	544	0.0e+00	807.8	COG4615	ABC-type siderophore export system, fused ATPase and permease components	546
2904475374	96	13.1	2	93	347	401	4.8e-05	16.9	COG2223	Nitrate/nitrite transporter NarK	417
2904475375	225	63.79	13	209	106	297	1.9e-24	81.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475376	428	99.52	1	419	2	414	0.0e+00	485.4	COG2733	Uncharacterized membrane-anchored protein YjiN, DUF445 family	415
2904475377	365	98.6	2	362	4	355	1.1e-103	341.1	COG0371	Glycerol dehydrogenase or related enzyme, iron-containing ADH family	360
2904475379	552	100	1	542	1	535	0.0e+00	756.7	COG3131	Periplasmic glucans biosynthesis protein	534
2904475381	283	80.3	154	282	20	125	3.7e-28	91.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904475382	612	95.41	1	463	21	457	7.4e-118	388.1	COG4289	Uncharacterized protein	458
2904475383	429	45.43	220	416	22	195	6.0e-12	24.1	COG0477	MFS family permease	338
2904475383	429	62.66	7	251	8	247	6.0e-12	19	COG0477	MFS family permease	338
2904475385	204	75	125	195	15	74	3.4e-13	42.8	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2904475386	566	90.59	63	528	41	425	1.1e-112	372	COG0840	Methyl-accepting chemotaxis protein	408
2904475389	69	100	3	69	1	67	3.7e-37	120.6	COG1278	Cold shock protein, CspA family	67
2904475390	307	70.4	78	274	18	174	4.3e-05	17.4	COG1226	Voltage-gated potassium channel Kch	212
2904475392	352	98.83	3	348	4	340	3.7e-130	428	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2904475393	333	91.67	1	331	13	342	4.1e-25	82.4	COG0628	Predicted PurR-regulated permease PerM	355
2904475394	219	98.04	13	216	3	202	1.5e-90	296.6	COG1636	Predicted ATPase, Adenine nucleotide alpha hydrolases (AANH) superfamily	204
2904475395	229	96.51	1	227	3	223	1.3e-102	336.4	COG3819	Uncharacterized membrane protein	229
2904475396	316	99.68	1	315	2	313	1.3e-126	416.4	COG3817	Uncharacterized membrane protein	313
2904475398	263	99.23	4	263	3	260	1.4e-77	254.8	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
2904475399	544	98.02	1	544	5	549	0.0e+00	581.9	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
2904475400	298	95.35	6	297	2	288	4.8e-46	152.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475401	168	89.71	2	167	5	161	1.0e-77	254.1	COG3479	Phenolic acid decarboxylase	175
2904475402	337	95.93	47	337	9	291	3.6e-40	132.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904475403	507	93.38	4	507	24	517	1.5e-79	258.9	COG4943	Environmental sensor c-di-GMP phosphodiesterase, contains periplasmic CSS-motif sensor and cytoplasmic EAL domain	524
2904475404	280	96.62	19	280	3	259	4.6e-110	361.6	COG3228	Mlc titration factor MtfA, regulates ptsG expression	266
2904475406	246	99.25	2	244	2	267	2.5e-50	165.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904475407	1029	99.9	7	1015	1	1013	0.0e+00	921.6	COG0841	Multidrug efflux pump subunit AcrB	1009
2904475408	369	95.64	1	361	15	387	6.4e-44	145.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904475409	187	79.9	1	186	15	181	6.5e-19	63.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904475410	483	97.83	13	482	2	451	9.5e-103	338.7	COG1538	Outer membrane protein TolC	457
2904475411	261	79.85	1	236	1	214	6.5e-22	72.6	COG0345	Pyrroline-5-carboxylate reductase	266
2904475412	272	95.9	1	246	3	259	1.2e-54	179.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904475413	260	98.11	1	258	4	263	3.0e-78	257	COG0300	Short-chain dehydrogenase	265
2904475414	363	98.62	1	363	3	360	5.0e-110	362.5	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2904475415	187	84.69	1	182	12	188	1.0e-18	62.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904475416	227	89.96	3	225	24	238	1.1e-47	156.8	COG2188	DNA-binding transcriptional regulator, GntR family	236
2904475417	260	97.17	2	260	2	276	6.7e-62	203.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904475418	325	90	2	325	32	337	2.0e-84	277.9	COG2222	Fructoselysine-6-P-deglycase FrlB and related proteins with duplicated sugar isomerase (SIS) domain	340
2904475419	270	94.3	2	267	2	299	3.0e-33	109.4	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2904475420	179	81.86	1	179	40	215	4.0e-88	289.3	COG3122	Uncharacterized conserved protein YaiL, DUF2058 family	215
2904475422	334	87.38	33	333	3	286	7.0e-58	185.1	COG3491	Isopenicillin N synthase and related dioxygenases	322
2904475423	478	97.17	3	467	6	417	5.4e-71	233.5	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2904475424	329	94.63	2	324	9	325	1.4e-29	97.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2904475425	307	96.68	5	301	6	296	8.3e-47	154.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475426	324	92.16	5	263	19	265	4.5e-48	158.1	COG1018	Ferredoxin-NADP reductase	266
2904475427	426	89.86	20	425	24	404	2.5e-27	89.5	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2904475428	153	91.18	2	151	12	135	4.6e-17	54.6	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2904475429	293	97.19	12	263	6	247	1.2e-66	219	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
2904475430	327	89.85	1	317	13	313	6.0e-31	102.1	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2904475431	275	96.81	22	273	5	247	8.1e-88	288.3	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2904475432	271	96.51	6	267	8	256	5.6e-66	216.9	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2904475433	466	93.18	28	450	31	467	7.5e-43	139.6	COG0277	FAD/FMN-containing dehydrogenase	459
2904475434	736	98.64	11	736	10	737	0.0e+00	1224.9	COG0376	Catalase (peroxidase I)	730
2904475435	341	95.04	8	335	8	333	6.9e-54	177.3	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2904475436	276	84.09	153	276	12	122	1.6e-21	70.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904475437	675	88.05	13	654	9	612	1.7e-72	238.8	COG1289	Uncharacterized membrane protein YccC	674
2904475439	305	92.9	7	300	16	342	4.3e-77	251.9	COG1566	Multidrug resistance efflux pump	352
2904475440	460	48.3	265	459	8	192	1.9e-37	26.6	COG0477	MFS family permease	338
2904475440	460	83.55	16	296	7	326	1.9e-37	100.9	COG0477	MFS family permease	338
2904475443	475	98.9	1	472	4	454	5.2e-126	415.3	COG2079	2-methylcitrate dehydratase PrpD	453
2904475444	295	98.34	1	290	1	296	3.0e-43	142.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475445	404	91	28	403	13	366	2.1e-54	178.8	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2904475446	278	73.85	10	275	26	217	1.8e-30	100.6	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2904475448	187	96.82	33	183	3	154	1.0e-37	123.8	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
2904475449	260	95.25	2	257	13	293	2.7e-38	126.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904475450	323	93.23	181	321	8	131	2.4e-17	56.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2904475450	323	95.76	3	174	3	160	7.3e-39	127	COG0835	Chemotaxis signal transduction protein	165
2904475451	325	99.7	1	323	1	330	5.7e-77	253.7	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2904475452	222	93.3	15	221	3	197	2.7e-20	68.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904475453	445	97.38	12	410	6	339	6.1e-88	289.4	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2904475454	328	95.92	10	327	8	336	5.0e-44	145	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2904475455	394	96.95	7	390	10	390	4.6e-129	425	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2904475456	310	89.4	2	302	21	273	1.2e-39	130.5	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904475457	171	85.19	1	140	16	153	1.7e-11	39.1	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904475458	305	94.74	27	285	11	226	2.4e-62	204.7	COG0765	ABC-type amino acid transport system, permease component	222
2904475459	281	98.76	31	281	3	241	9.5e-102	333.5	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2904475460	134	92.19	5	132	3	120	3.9e-45	147	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
2904475461	231	97.83	1	227	5	229	1.4e-92	303.6	COG1346	Putative effector of murein hydrolase	230
2904475462	320	24.23	192	320	291	384	5.1e-51	48.5	COG1344	Flagellin and related hook-associated protein FlgL	360
2904475462	320	52.58	1	233	1	204	5.1e-51	126.6	COG1344	Flagellin and related hook-associated protein FlgL	360
2904475463	550	99.83	1	550	1	587	0.0e+00	472.2	COG1256	Flagellar hook-associated protein FlgK	552
2904475464	316	80	1	316	50	273	2.3e-76	251.3	COG1705	Flagellum-specific peptidoglycan hydrolase FlgJ	201
2904475465	368	98.36	3	368	7	365	0.0e+00	497.8	COG1706	Flagellar basal body P-ring protein FlgI	365
2904475466	243	97.84	15	240	6	231	3.9e-83	272.8	COG2063	Flagellar basal body L-ring protein FlgH	230
2904475467	260	98.87	1	260	1	262	8.5e-107	350.9	COG4786	Flagellar basal body rod protein FlgG	265
2904475468	251	100	1	251	1	251	1.3e-111	366.6	COG4787	Flagellar basal body rod protein FlgF	251
2904475469	414	99.36	1	414	3	471	1.6e-121	401	COG1749	Flagellar hook protein FlgE	423
2904475470	234	96.41	1	234	8	222	1.7e-64	211.9	COG1843	Flagellar hook assembly protein FlgD	222
2904475471	134	100	1	134	1	138	3.7e-57	186.7	COG1558	Flagellar basal body rod protein FlgC	137
2904475472	136	98.52	2	136	2	134	2.1e-50	164.9	COG1815	Flagellar basal body rod protein FlgB	133
2904475473	243	91.36	20	243	18	218	6.7e-56	183.8	COG1261	Flagella basal body P-ring formation protein FlgA	220
2904475474	100	97.85	1	96	2	92	5.4e-23	75.9	COG2747	Negative regulator of flagellin synthesis (anti-sigma28 factor)	93
2904475475	150	98.63	1	150	2	145	8.7e-36	117.5	COG3418	Flagellar biosynthesis/type III secretory pathway chaperone	146
2904475477	694	99.43	2	694	3	695	0.0e+00	992	COG1298	Flagellar biosynthesis pathway, component FlhA	696
2904475478	384	98.9	1	363	3	361	0.0e+00	457.4	COG1377	Flagellar biosynthesis protein FlhB	363
2904475479	214	94.01	1	214	14	217	6.5e-102	334.2	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2904475480	129	91.73	1	127	4	125	1.7e-31	103.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2904475481	349	98.58	3	346	1	347	0.0e+00	488.1	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2904475482	290	98.52	27	289	1	266	4.9e-90	295.7	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2904475483	556	91.76	67	513	36	425	1.8e-105	348.2	COG0840	Methyl-accepting chemotaxis protein	408
2904475484	564	93.65	46	517	27	424	5.8e-116	382.5	COG0840	Methyl-accepting chemotaxis protein	408
2904475487	491	45.17	252	486	6	178	1.8e-36	5.4	COG0477	MFS family permease	338
2904475487	491	89.03	1	283	6	346	1.8e-36	117	COG0477	MFS family permease	338
2904475488	337	97.23	12	335	7	322	5.2e-94	309	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2904475492	421	97.59	1	360	3	367	6.2e-81	266.7	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2904475493	140	59.61	9	140	80	200	9.4e-33	107.8	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2904475496	129	74	1	126	12	122	5.6e-08	26.8	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
2904475498	78	33.75	1	58	1	27	2.1e-03	12.2	COG5645	Uncharacterized conserved protein YceK	80
2904475501	1061	6.42	870	1006	1020	1089	0.0e+00	13.7	COG4733	Phage-related protein, tail component	952
2904475501	1061	82.66	8	926	2	902	0.0e+00	1020.1	COG4733	Phage-related protein, tail component	952
2904475502	196	99	1	196	2	200	9.1e-58	189.4	COG4723	Phage-related protein, tail component	198
2904475504	111	73.68	1	108	2	85	3.5e-04	13.3	COG5294	Uncharacterized protein YxeA	113
2904475507	236	96.3	1	126	6	135	4.7e-32	105.1	COG1310	Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif	134
2904475508	552	13.85	1	67	9	40	4.7e-78	19.4	COG4672	Phage-related protein	231
2904475508	552	83.12	336	552	39	230	4.7e-78	234.6	COG4672	Phage-related protein	231
2904475509	118	99.1	1	114	1	110	2.9e-23	76.5	COG4718	Phage-related protein	111
2904475510	783	21.67	1	205	21	215	2.2e-114	88.2	COG5281	Phage-related minor tail protein	833
2904475510	783	51.11	279	776	438	897	2.2e-114	295.8	COG5281	Phage-related minor tail protein	833
2904475513	245	72.06	1	245	24	268	3.7e-53	175.2	COG5492	Uncharacterized conserved protein YjdB, contains Ig-like domain	329
2904475517	108	99.07	1	108	1	106	1.5e-31	103	COG5471	Predicted phage recombinase, RecA/RadA family	107
2904475518	676	88	7	202	24	199	1.5e-57	188.6	COG0740	ATP-dependent protease ClpP, protease subunit	200
2904475519	492	97.43	5	492	2	493	0.0e+00	627.6	COG5511	Bacteriophage capsid protein	492
2904475521	641	89.94	1	633	59	639	0.0e+00	767.2	COG5525	Phage terminase, large subunit GpA	611
2904475526	168	50.52	1	152	108	254	3.4e-05	17.6	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
2904475527	176	98.68	16	175	2	151	3.7e-46	151	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
2904475529	347	84.82	1	345	14	270	5.7e-42	130.3	COG0863	DNA modification methylase	302
2904475530	130	22.42	34	130	302	388	3.4e-29	96.2	COG3064	Membrane protein involved in colicin uptake	387
2904475533	231	97.78	96	229	2	133	1.8e-38	125.3	COG3645	Phage antirepressor protein YoqD, KilAC domain	135
2904475534	125	94.7	1	120	6	130	8.8e-22	72.1	COG4570	Holliday junction resolvase RusA (prophage-encoded endonuclease)	132
2904475535	154	8.7	39	72	6	31	8.3e-03	6.2	COG1405	Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB	285
2904475535	154	20.74	73	148	68	129	8.3e-03	6.1	COG1405	Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB	285
2904475540	305	63.29	35	98	23	72	1.3e-04	15.3	COG1654	Biotin operon repressor	79
2904475543	72	54.17	8	71	14	65	1.9e-04	15.8	COG4197	DNA-binding transcriptional regulator YdaS, prophage-encoded, Cro superfamily	96
2904475544	222	90.15	8	219	19	201	1.6e-34	113.6	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2904475547	381	94.93	76	380	7	324	1.3e-20	68.5	COG0582	Integrase	309
2904475548	165	88.48	5	163	15	160	1.3e-51	168.7	COG0835	Chemotaxis signal transduction protein	165
2904475549	680	20.42	1	177	4	157	0.0e+00	112.5	COG0643	Chemotaxis protein histidine kinase CheA	716
2904475549	680	67.11	167	679	242	747	0.0e+00	605.6	COG0643	Chemotaxis protein histidine kinase CheA	716
2904475550	367	98.52	9	268	4	269	4.9e-71	233.5	COG1360	Flagellar motor protein MotB	244
2904475551	296	98.5	1	285	4	266	3.8e-100	328.5	COG1291	Flagellar motor component MotA	266
2904475555	274	94.39	1	272	1	303	5.1e-36	119.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2904475557	289	97.95	1	289	7	293	1.3e-112	370.3	COG0040	ATP phosphoribosyltransferase	290
2904475558	437	98.6	10	434	5	427	0.0e+00	589.3	COG0141	Histidinol dehydrogenase	425
2904475559	377	97.78	12	359	2	354	6.4e-116	381.3	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2904475560	360	95.08	2	185	5	178	9.5e-63	204.8	COG0241	Histidinol phosphatase or a related phosphatase	181
2904475560	360	99.49	169	360	2	195	2.1e-88	289.3	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
2904475561	196	98.53	1	196	2	202	8.4e-78	255.2	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
2904475562	245	98.76	1	245	3	240	2.4e-91	299.6	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
2904475563	257	99.61	1	257	1	256	6.3e-115	377.2	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
2904475564	213	93.75	124	213	1	90	1.9e-35	115.1	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
2904475564	213	94.64	9	119	5	110	5.8e-39	126.5	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
2904475565	469	98.95	1	469	1	469	0.0e+00	785	COG0362	6-phosphogluconate dehydrogenase	473
2904475567	272	97.36	6	272	8	265	2.0e-67	221.5	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2904475568	463	96.02	23	265	2	242	4.1e-89	292.3	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
2904475569	1211	89	807	1194	6	369	1.9e-32	64.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904475569	1211	94.38	380	801	11	396	1.9e-32	40.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904475570	298	96.49	5	298	6	307	4.8e-28	92.4	COG1216	Glycosyltransferase, GT2 family	305
2904475571	277	78.27	7	267	4	248	6.1e-36	118.2	COG1216	Glycosyltransferase, GT2 family	305
2904475572	290	98.58	1	285	1	278	5.8e-98	321.8	COG1091	dTDP-4-dehydrorhamnose reductase	281
2904475573	178	96.61	1	175	5	175	5.2e-69	225.6	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
2904475574	354	98.57	1	354	1	345	0.0e+00	557.8	COG1088	dTDP-D-glucose 4,6-dehydratase	340
2904475575	290	98.97	1	289	2	289	2.2e-123	405.3	COG1209	dTDP-glucose pyrophosphorylase	286
2904475576	295	97.93	1	295	5	288	4.4e-122	401.1	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
2904475577	529	97.95	76	526	8	436	1.2e-112	371	COG1253	Hemolysin or related protein, contains CBS domains	429
2904475578	616	95.57	1	616	1	647	1.7e-88	292.3	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2904475579	193	99.46	1	192	1	184	5.6e-60	196.6	COG0717	Deoxycytidine triphosphate deaminase	183
2904475580	213	94.5	1	213	3	208	1.4e-88	290.4	COG0572	Uridine kinase	218
2904475581	370	95.8	46	324	12	285	2.5e-94	309.7	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2904475582	676	76.06	557	675	8	115	5.5e-36	117	COG0073	tRNA-binding EMAP/Myf domain	123
2904475582	676	99.46	2	548	3	558	0.0e+00	719.1	COG0143	Methionyl-tRNA synthetase	558
2904475583	90	84.13	25	86	10	62	2.1e-12	40.9	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2904475584	472	99.12	1	471	3	454	0.0e+00	433.3	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2904475585	296	97.01	7	296	2	293	1.2e-64	213.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475586	93	47.01	3	86	12	66	6.2e-04	13.9	COG3462	Uncharacterized membrane protein	117
2904475587	527	97.23	14	523	7	568	2.4e-92	304.8	COG0747	ABC-type transport system, periplasmic component	556
2904475588	315	99.37	1	315	1	316	9.5e-98	321.9	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904475589	275	88.26	1	270	26	288	2.1e-73	241.1	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904475590	547	99.46	1	523	2	550	0.0e+00	608.8	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2904475591	675	89.91	1	567	15	522	2.7e-129	426.8	COG2936	Predicted acyl esterase	563
2904475592	148	93.33	1	120	1	112	9.6e-27	87.2	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2904475593	264	97.74	4	263	6	264	2.1e-76	250.9	COG0300	Short-chain dehydrogenase	265
2904475594	229	79.12	4	229	55	270	2.1e-71	235	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2904475597	493	98.48	16	481	5	459	0.0e+00	604.9	COG1113	L-asparagine transporter and related permeases	462
2904475598	282	58	1	276	205	494	5.5e-63	207.6	COG3711	Transcriptional antiterminator	491
2904475599	465	98.7	2	464	2	458	0.0e+00	592.3	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2904475600	624	84.27	4	89	3	77	1.8e-26	85.7	COG1264	Phosphotransferase system IIB components	88
2904475600	624	88.46	471	623	5	142	2.1e-50	164.2	COG2190	Phosphotransferase system IIA component	156
2904475600	624	95.71	91	474	4	405	1.2e-64	212.9	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
2904475601	257	99.25	5	253	2	267	2.3e-75	247.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904475602	299	95.35	4	298	4	290	5.0e-64	211.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475603	470	96.13	4	453	8	454	0.0e+00	473	COG2211	Na+/melibiose symporter or related transporter	467
2904475604	792	99.76	23	472	1	416	8.1e-94	309.3	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2904475605	335	98.8	4	335	2	329	0.0e+00	547.2	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
2904475606	204	99	1	204	2	200	5.6e-73	239.1	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
2904475607	173	97.52	5	163	1	157	1.0e-67	221.2	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
2904475608	247	99.59	1	242	1	242	9.8e-102	334	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
2904475609	148	75	1	143	21	149	3.4e-20	67.1	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2904475610	598	99.66	1	586	1	584	0.0e+00	873.6	COG0173	Aspartyl-tRNA synthetase	585
2904475611	191	98.06	3	191	1	202	4.2e-41	135.4	COG1335	Nicotinamidase-related amidase	205
2904475612	272	96.62	1	269	3	259	1.4e-66	219.2	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
2904475613	131	96.18	1	127	5	130	1.2e-52	171.4	COG3788	Uncharacterized membrane protein YecN, MAPEG domain	131
2904475614	247	78.24	43	247	49	235	2.8e-11	37.2	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2904475615	323	68.1	32	320	36	225	1.5e-12	42.5	COG0500	SAM-dependent methyltransferase	257
2904475618	167	74.22	4	146	25	119	1.1e-03	12.8	COG3755	Uncharacterized conserved protein YecT, DUF1311 family	127
2904475619	252	99.59	1	244	1	240	4.1e-90	295.7	COG3142	Copper homeostasis protein CutC	241
2904475620	382	99.22	2	381	2	384	7.7e-113	371.6	COG1168	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	388
2904475621	186	97.3	1	182	6	185	1.2e-75	247.4	COG3102	Uncharacterized conserved protein YecM, predicted metalloenzyme	185
2904475622	577	99.83	1	577	2	581	0.0e+00	685.4	COG0018	Arginyl-tRNA synthetase	577
2904475623	511	99.03	1	510	5	517	0.0e+00	670.8	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
2904475624	303	96.01	1	303	3	339	7.0e-52	170.9	COG0673	Predicted dehydrogenase	342
2904475625	219	100	1	217	1	215	4.0e-105	344.8	COG3132	Uncharacterized conserved protein YceH, UPF0502 family	215
2904475626	195	95.72	5	194	6	184	3.0e-48	158.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2904475627	370	49.09	2	204	46	233	2.9e-21	54	COG0477	MFS family permease	338
2904475627	370	51.17	169	369	10	205	2.9e-21	20.7	COG0477	MFS family permease	338
2904475628	215	98.6	1	215	1	212	2.2e-100	329	COG2999	Glutaredoxin 2	215
2904475630	194	94.61	1	185	7	199	2.9e-58	190.9	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
2904475631	246	99.17	3	236	2	241	2.0e-60	198.8	COG1387	Histidinol phosphatase or related hydrolase of the PHP family	237
2904475632	313	87.73	15	313	41	326	6.2e-68	223.2	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2904475633	493	98.2	1	490	8	497	1.1e-80	266.2	COG3104	Dipeptide/tripeptide permease	498
2904475636	326	98.77	1	326	2	321	3.1e-110	362.5	COG2988	Succinylglutamate desuccinylase	324
2904475637	447	99.77	1	447	1	441	0.0e+00	721.7	COG3724	Succinylarginine dihydrolase	442
2904475638	492	96.24	4	474	3	463	1.2e-129	427.1	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2904475639	357	100	1	338	1	336	0.0e+00	496.8	COG3138	Arginine/ornithine N-succinyltransferase beta subunit	336
2904475640	406	97.53	3	406	6	400	0.0e+00	544.9	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2904475641	328	91.74	1	314	11	310	3.0e-69	227.7	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2904475642	512	98.4	14	512	6	498	0.0e+00	591.6	COG1129	ABC-type sugar transport system, ATPase component	500
2904475643	329	97.18	3	327	7	316	3.2e-87	286.7	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2904475644	317	94.67	6	317	11	312	1.5e-82	271.3	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2904475645	546	98.17	1	546	1	535	0.0e+00	699.3	COG1069	Ribulose kinase	544
2904475646	202	92.57	8	201	8	194	1.8e-53	175.1	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
2904475647	477	99.34	1	476	1	453	0.0e+00	452.2	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2904475648	169	99.38	1	162	2	160	3.8e-38	125.4	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
2904475649	688	99.51	32	685	1	608	0.0e+00	869.5	COG1966	Carbon starvation protein CstA	575
2904475650	101	96.92	34	100	3	65	2.4e-28	91.9	COG2879	Uncharacterized short protein YbdD, DUF466 family	65
2904475652	308	83.72	1	295	1	252	3.1e-59	195.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475653	261	98.88	3	260	3	267	2.8e-55	182	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904475654	299	26.29	1	73	18	78	1.7e-52	58.4	COG1802	DNA-binding transcriptional regulator, GntR family	230
2904475654	299	90.52	75	297	14	223	1.7e-52	117.3	COG1802	DNA-binding transcriptional regulator, GntR family	230
2904475655	272	96.11	4	271	3	274	3.0e-46	152.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904475656	237	92.11	1	218	18	227	1.7e-72	237.9	COG0765	ABC-type amino acid transport system, permease component	222
2904475657	247	98.76	6	246	3	241	1.0e-103	339.9	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2904475658	387	96.41	4	387	14	416	2.4e-92	304.3	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2904475659	365	88.2	8	363	35	363	2.2e-52	172.1	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2904475660	394	96.67	16	393	3	379	9.7e-85	279.1	COG0006	Xaa-Pro aminopeptidase	384
2904475661	306	96.99	7	300	3	292	9.6e-58	189.4	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2904475662	400	45.98	119	400	286	531	4.7e-57	187.8	COG0504	CTP synthase (UTP-ammonia lyase)	533
2904475663	402	98.99	8	402	4	395	1.2e-114	377.6	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2904475666	216	75.85	1	204	1	201	8.8e-61	199.7	COG3342	Uncharacterized conserved protein, Ntn-hydrolase superfamily	265
2904475667	515	94.64	2	515	23	569	2.1e-125	414	COG0747	ABC-type transport system, periplasmic component	556
2904475668	311	97.48	1	311	6	315	1.1e-118	390.4	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904475669	598	84.62	316	597	1	275	6.0e-107	351.4	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2904475669	598	94.3	3	290	16	296	9.3e-92	301.1	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904475670	261	46.92	1	261	290	548	2.7e-95	314.3	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2904475671	257	97.1	6	250	5	238	2.3e-38	126.1	COG2186	DNA-binding transcriptional regulator, FadR family	241
2904475673	234	96.51	1	228	6	226	1.1e-77	254.5	COG3382	B3/B4 domain (DNA/RNA-binding domain of Phe-tRNA-synthetase)	229
2904475674	198	53.85	19	134	3	72	1.2e-12	43	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2904475675	304	90.71	74	302	17	182	1.4e-43	143.1	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904475676	345	99.34	46	344	2	300	1.2e-57	189.8	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2904475677	562	98.16	17	562	6	539	2.0e-127	420.1	COG1178	ABC-type Fe3+ transport system, permease component	540
2904475678	231	61.47	1	230	3	219	5.2e-85	280	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2904475679	160	96.91	1	160	4	160	3.1e-67	219.2	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
2904475680	201	86.54	1	199	4	183	7.6e-15	49.4	COG0125	Thymidylate kinase	208
2904475681	98	88.12	1	95	8	96	2.1e-21	70.3	COG1605	Chorismate mutase	101
2904475682	179	62.02	47	178	77	205	6.2e-26	84.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2904475684	207	94.83	6	174	4	168	2.3e-41	135.7	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2904475686	352	97.5	1	322	1	312	1.7e-111	366.3	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2904475687	92	72.83	1	92	17	83	1.6e-09	32.5	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
2904475688	191	93.72	2	175	2	180	2.1e-35	116.4	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
2904475689	299	96.35	4	299	3	292	1.6e-65	216.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475690	311	89.73	1	306	1	297	1.0e-40	134.1	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2904475691	160	81.95	21	152	22	130	8.8e-15	49	COG1846	DNA-binding transcriptional regulator, MarR family	126
2904475692	52	10.43	2	52	401	448	2.6e-16	52.7	COG1538	Outer membrane protein TolC	457
2904475694	351	81.93	8	294	5	267	1.4e-21	71.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2904475695	298	98.01	3	293	2	296	4.7e-54	178.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475696	142	74.1	11	139	41	163	3.8e-16	53.2	COG4925	Uncharacterized protein	166
2904475697	342	97.4	20	342	8	307	4.7e-50	164.5	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
2904475698	398	98.23	6	397	3	390	4.0e-116	381.9	COG2814	Predicted arabinose efflux permease, MFS family	394
2904475699	296	97.34	3	296	2	294	3.5e-68	224.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475700	170	65.08	3	161	41	163	2.8e-09	31.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2904475701	290	98.34	1	290	1	296	2.1e-49	163.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475702	420	95.7	10	415	12	389	1.5e-34	113.1	COG2814	Predicted arabinose efflux permease, MFS family	394
2904475704	262	50.51	1	260	6	154	2.5e-14	47.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904475705	1024	99.8	11	1014	1	1012	0.0e+00	858.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2904475706	380	94.87	12	377	12	381	3.4e-45	148.8	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904475708	261	97.67	2	261	7	258	3.0e-36	119.5	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
2904475711	477	94.57	2	477	26	495	0.0e+00	463.8	COG1621	Sucrose-6-phosphate hydrolase SacC, GH32 family	486
2904475712	413	49.35	210	410	8	196	1.4e-09	16.3	COG0477	MFS family permease	338
2904475712	413	59.53	3	245	5	232	1.4e-09	19.4	COG0477	MFS family permease	338
2904475713	338	99.1	2	335	2	332	9.7e-75	246.1	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904475714	257	98.51	4	255	4	267	1.5e-46	153.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904475715	302	98.01	2	301	2	296	8.5e-71	233.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475716	232	70.89	5	232	82	288	2.2e-62	205.3	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2904475717	439	45.17	250	439	17	189	5.1e-35	23.8	COG0477	MFS family permease	338
2904475717	439	65.54	19	299	2	252	5.1e-35	94	COG0477	MFS family permease	338
2904475718	213	93.95	2	211	3	204	1.8e-49	162.7	COG0625	Glutathione S-transferase	211
2904475719	482	99.58	202	462	1	236	4.5e-73	239.5	COG0775	Nucleoside phosphorylase	234
2904475720	476	96.52	9	475	14	457	3.9e-119	392.2	COG0534	Na+-driven multidrug efflux pump	455
2904475721	229	98.21	7	229	1	220	3.6e-67	220.3	COG4565	Response regulator of citrate/malate metabolism	224
2904475722	481	84.17	1	461	80	531	0.0e+00	455.6	COG3290	Sensor histidine kinase regulating citrate/malate metabolism	537
2904475723	454	97.72	15	453	10	438	1.3e-130	430.2	COG3493	Na+/citrate or Na+/malate symporter	438
2904475724	295	88.64	8	279	31	272	2.0e-75	248	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2904475725	364	92.61	8	355	14	339	9.1e-125	410.2	COG3053	Citrate lyase synthetase	352
2904475726	96	98.98	1	96	1	97	1.1e-36	119.5	COG3052	Citrate lyase, gamma subunit	98
2904475727	291	99.3	7	291	1	283	4.6e-102	335.2	COG2301	Citrate lyase beta subunit	283
2904475728	508	93.76	4	506	33	513	0.0e+00	835.3	COG3051	Citrate lyase, alpha subunit	513
2904475729	179	90.16	2	179	11	175	2.9e-51	167.6	COG3697	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase)	182
2904475730	279	97.59	8	279	4	286	5.2e-69	227	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
2904475731	182	95.58	6	178	6	178	1.1e-46	152.7	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
2904475732	158	88.19	4	155	4	130	3.8e-23	75.8	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
2904475733	356	99.4	6	333	2	333	3.3e-87	287.1	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904475734	418	100	1	418	1	430	0.0e+00	476.8	COG4580	Maltoporin (phage lambda and maltose receptor)	429
2904475735	105	87.64	25	105	3	80	7.5e-22	71.2	COG1264	Phosphotransferase system IIB components	88
2904475736	689	97.95	5	684	14	682	0.0e+00	764.5	COG1874	Beta-galactosidase GanA	673
2904475737	403	95.79	1	403	7	393	0.0e+00	565.5	COG3867	Arabinogalactan endo-1,4-beta-galactosidase	403
2904475738	283	98.25	1	283	6	285	2.9e-113	372.1	COG3833	ABC-type maltose transport system, permease component	282
2904475739	435	43.3	9	111	13	54	7.8e-02	14.7	COG2314	Uncharacterized membrane protein YozV, TM2 domain	95
2904475739	435	96.64	122	433	8	295	1.4e-89	294.8	COG1175	ABC-type sugar transport system, permease component	295
2904475740	408	92.43	1	406	31	421	1.1e-121	400.8	COG2182	Maltose-binding periplasmic protein MalE	420
2904475741	367	99.71	1	354	1	349	0.0e+00	467.2	COG3839	ABC-type sugar transport system, ATPase component	338
2904475742	319	92.33	7	318	12	312	4.6e-87	285.9	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2904475743	110	98.17	1	110	1	107	1.1e-56	183.7	COG2926	Uncharacterized conserved protein YeeX, DUF496 family	109
2904475744	365	46.21	2	347	356	672	7.9e-50	163.9	COG1289	Uncharacterized membrane protein YccC	674
2904475745	475	99.16	1	474	5	475	0.0e+00	805	COG2925	Exonuclease I	475
2904475746	458	94.72	7	456	3	468	3.0e-73	241.2	COG0531	Amino acid transporter	466
2904475748	480	98.43	31	479	7	445	2.6e-121	399.6	COG0174	Glutamine synthetase	443
2904475749	267	97.95	15	261	3	241	2.5e-74	244	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
2904475750	185	60.77	7	116	3	81	2.1e-16	54.8	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2904475751	437	98.71	36	417	4	386	1.7e-79	261.9	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2904475753	575	99.13	2	575	2	570	0.0e+00	844.5	COG3263	NhaP-type Na+/H+ and K+/H+ antiporter with C-terminal TrkAC and CorC domains	574
2904475754	110	42.67	1	109	8	71	6.0e-10	31.4	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
2904475755	167	94.48	2	164	10	163	9.2e-49	159.3	COG4297	Uncharacterized protein YjlB	163
2904475756	541	93.88	57	538	25	423	6.5e-78	256.9	COG0840	Methyl-accepting chemotaxis protein	408
2904475757	356	97.45	1	355	6	349	4.2e-108	356	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2904475758	589	98.16	6	589	7	540	0.0e+00	473.6	COG1178	ABC-type Fe3+ transport system, permease component	540
2904475759	362	99	59	362	1	298	6.8e-57	187.1	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2904475760	296	93.46	1	292	2	301	2.8e-34	113.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2904475761	305	86.36	176	303	10	123	2.9e-29	95.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904475764	224	99.14	1	224	1	230	3.7e-56	184.4	COG0670	Integral membrane protein, interacts with FtsH	233
2904475765	109	98.2	1	109	3	111	1.2e-55	180.8	COG2920	Sulfur relay (sulfurtransferase) protein, DsrC/TusE family	111
2904475766	92	97.85	1	92	3	93	1.5e-30	99.8	COG1254	Acylphosphatase	92
2904475767	397	99.49	5	396	2	392	0.0e+00	474.8	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
2904475768	105	90.52	1	105	10	114	3.1e-39	128	COG3785	Heat shock protein HspQ	116
2904475769	137	95.71	1	137	5	138	2.3e-57	186.6	COG1832	Predicted CoA-binding protein	140
2904475770	219	93.98	2	219	4	206	1.6e-47	155.7	COG3110	Uncharacterized conserved protein YccT, UPF0319 family	216
2904475771	153	97.89	8	149	2	140	2.3e-69	225.9	COG1803	Methylglyoxal synthase	142
2904475772	684	9.24	65	191	102	163	1.2e-81	6	COG0210	Superfamily I DNA or RNA helicase	655
2904475772	684	21.46	542	684	520	663	1.2e-81	79.3	COG0210	Superfamily I DNA or RNA helicase	655
2904475772	684	48.44	195	544	2	326	1.2e-81	185.6	COG0210	Superfamily I DNA or RNA helicase	655
2904475773	153	99.31	1	146	1	144	9.8e-69	224.1	COG3304	Uncharacterized membrane protein YccF, DUF307 family	145
2904475774	713	98.69	7	712	2	678	0.0e+00	685.5	COG1289	Uncharacterized membrane protein YccC	674
2904475775	210	97.52	3	123	4	121	7.7e-24	77.6	COG3070	Transcriptional regulator of competence genes, TfoX/Sxy family	121
2904475776	168	100	1	168	1	169	3.7e-60	196.8	COG5404	Cell division inhibitor SulA, prevents FtsZ ring assembly	169
2904475777	358	92.46	145	349	14	197	1.8e-51	169.1	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2904475778	153	100	1	149	1	149	3.6e-80	261.5	COG3120	Macrodomain Ter protein organizer, MatP/YcbG family	149
2904475779	588	70.52	49	574	182	626	3.9e-123	406.4	COG1067	Predicted ATP-dependent protease	647
2904475780	172	96.62	13	168	5	147	1.1e-44	146.1	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2904475781	188	98.42	1	188	1	187	1.2e-65	214.9	COG3009	Uncharacterized lipoprotein YmbA	190
2904475782	550	99.28	1	550	4	552	0.0e+00	661.4	COG3008	Paraquat-inducible protein B	553
2904475783	403	93.06	1	399	28	416	0.0e+00	509.1	COG2995	Uncharacterized paraquat-inducible protein A	418
2904475784	634	18.69	516	627	231	330	0.0e+00	5.3	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2904475784	634	99.63	1	533	1	533	0.0e+00	585.6	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2904475785	706	24.67	548	687	258	351	0.0e+00	6	COG0116	23S rRNA G2445 N2-methylase RlmL	381
2904475785	706	98.95	1	384	2	378	0.0e+00	497.2	COG0116	23S rRNA G2445 N2-methylase RlmL	381
2904475786	367	81.55	277	367	10	93	6.8e-17	54.5	COG0633	Ferredoxin	102
2904475786	367	98.52	1	272	4	269	2.5e-106	349.1	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
2904475788	336	91.94	41	336	4	288	7.6e-111	364.2	COG0167	Dihydroorotate dehydrogenase	310
2904475789	193	95.65	1	184	1	176	2.0e-41	135.9	COG0431	NAD(P)H-dependent FMN reductase	184
2904475790	324	95.82	6	324	5	325	1.6e-71	235.4	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2904475791	384	98.54	8	356	1	338	1.8e-87	287.8	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2904475792	263	97.67	1	256	6	257	2.3e-93	306.6	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2904475793	260	96.81	10	250	4	246	3.7e-88	289.3	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2904475794	871	99.42	1	864	5	866	0.0e+00	994.8	COG0308	Aminopeptidase N	859
2904475795	401	91.95	1	401	6	382	1.1e-115	380.9	COG1488	Nicotinic acid phosphoribosyltransferase	405
2904475796	466	98.4	1	466	7	437	0.0e+00	579.2	COG0017	Aspartyl/asparaginyl-tRNA synthetase	435
2904475797	370	100	2	370	1	360	6.3e-121	398	COG3203	Outer membrane protein (porin)	354
2904475798	396	100	1	396	1	396	0.0e+00	594.9	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
2904475799	215	90.38	1	213	19	253	1.0e-51	170.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2904475800	183	98.38	1	183	1	182	2.1e-72	237.3	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
2904475801	614	88.17	20	614	68	574	0.0e+00	674.7	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
2904475802	1482	99.66	1	1480	1	1475	0.0e+00	2810.8	COG3096	Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Escherichia coli str. K-12 substr. MG1655	1480
2904475803	243	99.16	3	242	2	237	0.0e+00	453.4	COG3095	Chromosome condensin MukBEF, MukE localization factor	238
2904475804	440	100	1	440	1	440	0.0e+00	880.9	COG3006	Chromosome condensin MukBEF complex, kleisin-like MukF subunit	440
2904475805	261	70.49	5	234	59	230	1.1e-16	54.7	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2904475806	259	98.27	16	253	2	228	7.9e-44	144.1	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
2904475807	297	75.52	6	294	56	271	1.3e-08	28.3	COG3001	Fructosamine-3-kinase	286
2904475808	252	97.98	1	252	2	243	1.9e-112	368.6	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
2904475809	60	96.97	1	60	1	64	3.9e-26	85	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
2904475810	407	96.26	1	404	1	386	0.0e+00	492.5	COG3214	Uncharacterized conserved protein YcaQ, contains winged helix DNA-binding domain	400
2904475811	70	95.52	3	70	3	66	6.8e-22	71.6	COG1278	Cold shock protein, CspA family	67
2904475813	69	97.01	3	69	2	66	4.3e-34	110.7	COG1278	Cold shock protein, CspA family	67
2904475814	329	97.92	1	327	4	332	3.9e-125	411.6	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
2904475815	582	99.83	10	582	1	591	0.0e+00	623.5	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2904475816	409	98.69	105	397	5	305	2.3e-88	289.9	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
2904475817	333	71.16	1	333	24	361	1.5e-51	170.2	COG0658	Predicted membrane metal-binding protein	453
2904475818	94	95.74	1	94	2	91	1.1e-34	112.9	COG0776	Bacterial nucleoid DNA-binding protein	94
2904475819	569	99.64	13	562	1	548	0.0e+00	799	COG0539	Ribosomal protein S1	541
2904475820	232	95.98	2	226	5	219	7.1e-88	287.9	COG0283	Cytidylate kinase	222
2904475821	435	96.74	9	434	11	426	0.0e+00	536.3	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
2904475822	361	99.19	1	361	3	369	0.0e+00	521.6	COG1932	Phosphoserine aminotransferase	365
2904475823	587	98.5	1	422	4	398	0.0e+00	511.3	COG1944	Ribosomal protein S12 methylthiotransferase accessory factor YcaO	398
2904475824	285	98.49	5	285	3	263	8.5e-105	343.6	COG2116	Formate/nitrite transporter FocA, FNT family	265
2904475825	760	99.21	2	759	6	754	0.0e+00	1229	COG1882	Pyruvate-formate lyase	755
2904475826	246	97.58	1	246	3	244	5.3e-88	288.5	COG1180	Pyruvate-formate lyase-activating enzyme	260
2904475827	365	44.91	1	178	17	188	1.1e-27	58.7	COG0477	MFS family permease	338
2904475827	365	48.3	177	360	10	194	1.1e-27	39.1	COG0477	MFS family permease	338
2904475828	190	53.23	113	189	39	104	9.9e-17	22.1	COG1145	Ferredoxin	99
2904475828	190	55.65	26	125	37	105	9.9e-17	39	COG1145	Ferredoxin	99
2904475829	202	93.63	1	198	9	199	1.4e-63	208	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
2904475830	285	100	4	285	1	281	8.8e-102	334.5	COG3302	DMSO reductase anchor subunit	281
2904475831	205	91.71	1	202	10	197	2.9e-64	210.4	COG0437	Fe-S-cluster-containing dehydrogenase component	203
2904475832	815	99.75	14	815	2	809	0.0e+00	716.7	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2904475833	818	99.75	14	818	2	809	0.0e+00	702.7	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2904475834	430	99.07	1	430	1	427	0.0e+00	623.4	COG0172	Seryl-tRNA synthetase	429
2904475835	447	97.94	3	443	8	435	0.0e+00	639.6	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
2904475836	203	97.65	1	202	5	212	4.6e-60	197.1	COG2834	Outer membrane lipoprotein-sorting protein	211
2904475837	1148	99.57	7	1148	1	928	0.0e+00	1154.1	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2904475838	164	94.3	7	162	4	152	2.6e-49	161.5	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2904475839	322	98.7	4	318	2	304	5.6e-126	413.9	COG0492	Thioredoxin reductase	305
2904475840	588	99.28	23	587	1	555	0.0e+00	711.3	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
2904475841	574	99.48	2	574	1	570	0.0e+00	766.1	COG4987	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components	573
2904475842	244	97.29	11	230	2	216	8.8e-91	296.7	COG2360	Leu/Phe-tRNA-protein transferase	221
2904475843	72	96	1	72	1	72	1.2e-38	124.8	COG0361	Translation initiation factor IF-1	75
2904475844	760	41.37	413	748	469	801	0.0e+00	452.6	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2904475844	760	49.94	1	420	2	403	0.0e+00	512.9	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2904475845	106	90.65	2	106	10	106	3.0e-45	146.8	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
2904475846	73	97.01	1	67	1	65	1.0e-33	109.4	COG1278	Cold shock protein, CspA family	67
2904475847	329	95.02	9	315	15	300	6.8e-85	278.9	COG2990	Uncharacterized protein VirK/YbjX	300
2904475848	577	3.87	1	26	1	23	0.0e+00	13.8	COG3593	Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains	581
2904475848	577	95.79	42	577	25	593	0.0e+00	506.4	COG3593	Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains	581
2904475849	299	99.67	1	299	1	298	3.0e-117	385.5	COG2431	Uncharacterized membrane protein YbjE, DUF340 family	297
2904475850	550	96.71	1	550	4	561	0.0e+00	690.1	COG1151	Hydroxylamine reductase (hybrid-cluster protein)	576
2904475851	337	98.51	12	278	5	268	3.4e-70	230.5	COG1018	Ferredoxin-NADP reductase	266
2904475852	573	98.92	2	551	3	551	0.0e+00	567.7	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2904475853	337	99.42	1	334	2	342	3.0e-126	415.2	COG2008	Threonine aldolase	342
2904475854	531	99.64	55	333	2	276	7.0e-54	177	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2904475855	344	99.07	1	333	2	319	3.0e-58	191.9	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2904475856	282	95.79	11	276	12	261	1.3e-89	294.1	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
2904475857	108	99.07	1	108	1	107	2.3e-45	147.5	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
2904475859	249	100	8	249	1	242	0.0e+00	473.7	COG4161	ABC-type arginine transport system, ATPase component	242
2904475860	243	94.7	1	243	5	272	1.0e-73	242.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904475861	238	96.52	1	237	7	228	4.1e-97	318.2	COG4215	ABC-type arginine transport system, permease component	230
2904475862	222	97.37	1	221	6	227	2.5e-92	302.7	COG4160	ABC-type arginine/histidine transport system, permease component	228
2904475863	244	94.35	1	244	6	272	2.7e-71	234.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904475864	294	45.99	184	273	9	71	5.3e-45	21	COG0295	Cytidine deaminase	134
2904475864	294	94.89	42	172	7	136	5.3e-45	124.3	COG0295	Cytidine deaminase	134
2904475865	565	99.77	50	561	1	441	0.0e+00	499.1	COG0281	Malic enzyme	432
2904475866	307	94.89	1	226	13	235	1.7e-105	345.6	COG2949	Uncharacterized periplasmic protein SanA, affects membrane permeability for vancomycin	235
2904475867	336	100	1	336	1	336	0.0e+00	611.2	COG4211	ABC-type glucose/galactose transport system, permease component	336
2904475868	510	98.8	10	509	5	499	0.0e+00	664.5	COG1129	ABC-type sugar transport system, ATPase component	500
2904475869	332	95.41	1	332	7	318	2.1e-80	264.3	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2904475870	343	99.4	2	336	1	332	1.8e-103	340.5	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904475871	384	96.53	1	384	11	399	1.1e-112	371.4	COG2311	Uncharacterized membrane protein YeiB	394
2904475872	221	95.94	21	220	8	196	9.7e-76	247.5	COG0302	GTP cyclohydrolase I	195
2904475873	375	46.21	194	373	8	184	2.2e-05	7.1	COG0477	MFS family permease	338
2904475873	375	79.9	1	303	8	313	2.2e-05	10.1	COG0477	MFS family permease	338
2904475874	309	97.67	1	288	1	294	1.5e-58	192.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475875	374	100	4	372	1	366	0.0e+00	570.2	COG1062	Zn-dependent alcohol dehydrogenase	366
2904475876	285	97.84	1	284	4	320	1.7e-90	297.7	COG0627	S-formylglutathione hydrolase FrmB	316
2904475877	306	96.98	20	306	8	296	4.5e-104	341.7	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904475878	306	99.37	1	306	1	316	1.2e-118	390.4	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904475879	518	98.27	1	518	4	571	2.0e-118	391.1	COG0747	ABC-type transport system, periplasmic component	556
2904475880	618	99.28	8	571	4	551	0.0e+00	740.3	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2904475881	334	99.03	15	332	2	306	1.9e-112	369.8	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
2904475882	399	96.22	3	397	12	418	1.8e-20	65	COG0738	Fucose permease	422
2904475883	939	68.24	219	938	197	645	2.2e-32	106.9	COG3468	Type V secretory pathway, adhesin AidA	644
2904475884	77	24.8	1	74	2	64	3.7e-22	73.3	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2904475885	413	98.53	1	411	4	404	0.0e+00	498.8	COG0303	Molybdopterin biosynthesis enzyme	404
2904475886	253	98.47	5	253	2	258	8.7e-87	284.7	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
2904475887	531	98.88	1	530	4	532	0.0e+00	620.8	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2904475888	295	98.59	1	295	5	284	6.4e-123	404	COG3248	Nucleoside-specific outer membrane channel protein Tsx	284
2904475890	95	59.73	2	95	60	148	9.0e-28	91.4	COG5642	Uncharacterized conserved protein, DUF2384 family	149
2904475891	152	92.26	1	152	13	167	9.4e-32	104.6	COG5654	Uncharacterized conserved protein, contains RES domain	163
2904475892	146	94.7	1	145	6	148	1.4e-30	100.5	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
2904475893	145	96.69	1	145	1	146	2.6e-27	89.8	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
2904475894	310	99.67	7	308	1	300	3.2e-67	221.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475895	152	96.13	5	152	3	151	2.0e-56	184.3	COG2153	Predicted N-acyltransferase, GNAT family	155
2904475896	561	97.89	1	545	7	562	0.0e+00	529.9	COG2303	Choline dehydrogenase or related flavoprotein	542
2904475897	489	98.96	7	484	2	475	0.0e+00	591.3	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2904475898	199	83.25	1	197	12	185	2.1e-20	68.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904475899	684	99.44	9	567	3	538	0.0e+00	704.8	COG1292	Choline-glycine betaine transporter	537
2904475900	291	97.97	7	291	5	293	1.1e-40	134.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904475901	468	99.07	1	468	3	427	0.0e+00	583.6	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
2904475902	202	96.89	1	202	1	187	1.1e-63	208.8	COG0066	3-isopropylmalate dehydratase small subunit	191
2904475903	304	98.01	10	304	4	298	5.4e-67	220.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475904	370	97.42	7	324	7	308	8.0e-54	177.1	COG3021	Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily	309
2904475905	558	98.38	1	558	6	552	0.0e+00	488.2	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
2904475906	478	88.83	46	476	39	388	9.5e-59	193.9	COG0642	Signal transduction histidine kinase	336
2904475907	224	99.14	1	223	1	230	1.2e-81	267.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904475909	213	87.33	2	203	21	213	2.8e-62	204.3	COG4117	Thiosulfate reductase cytochrome b subunit	221
2904475910	254	87.2	21	254	4	255	5.3e-64	210.4	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2904475911	177	100	1	177	1	236	1.5e-32	107.4	COG3637	Opacity protein and related surface antigens	199
2904475912	328	98.29	27	317	5	291	6.4e-117	383.8	COG5006	Threonine/homoserine efflux transporter RhtA	292
2904475914	187	75.61	4	187	46	200	5.6e-49	161.1	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
2904475915	193	93.55	18	193	4	177	4.0e-42	138.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2904475916	225	93.33	1	224	13	236	1.4e-42	139.1	COG5343	Anti-sigma-K factor RskA	240
2904475917	167	98.73	14	167	3	157	2.3e-49	161.6	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
2904475919	268	91.7	7	266	17	259	1.7e-55	182	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2904475920	221	87.25	1	220	26	244	2.3e-71	234.3	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
2904475923	767	81.06	6	628	4	294	1.9e-28	90.7	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2904475926	423	96.28	2	400	6	393	3.7e-118	388.8	COG3562	Capsule polysaccharide modification protein KpsS	403
2904475927	679	98.37	1	676	6	668	0.0e+00	708.3	COG3563	Capsule polysaccharide export protein KpsC/LpsZ	671
2904475928	558	40.96	415	545	112	213	3.3e-37	15.3	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2904475928	558	86.35	47	279	20	234	3.3e-37	106.4	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2904475929	362	92.74	6	362	27	371	3.2e-83	273.9	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
2904475930	88	68.33	1	81	36	117	6.1e-19	62.9	COG1734	RNA polymerase-binding transcription factor DksA	120
2904475931	247	96.11	1	247	1	272	2.9e-73	240.9	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904475932	219	93.86	1	219	13	226	1.2e-72	238.5	COG0765	ABC-type amino acid transport system, permease component	222
2904475933	240	99.17	1	240	2	241	6.1e-112	366.8	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2904475936	436	49.17	5	131	121	239	8.9e-25	39.4	COG2202	PAS domain	232
2904475936	436	49.17	128	253	122	240	8.9e-25	38.9	COG2202	PAS domain	232
2904475937	322	98.29	33	322	2	288	3.0e-117	385.5	COG3129	23S rRNA A1618 N6-methylase RlmF	292
2904475938	209	92.97	3	201	8	179	1.2e-40	133.2	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2904475939	620	19.03	332	478	382	495	3.7e-23	34.2	COG1164	Oligoendopeptidase F	598
2904475939	620	52.42	15	338	4	317	3.7e-23	40.2	COG1164	Oligoendopeptidase F	598
2904475940	113	99.11	2	113	2	112	1.1e-53	174.2	COG2824	Uncharacterized Zn-ribbon-containing protein	112
2904475941	320	93.24	1	320	2	318	4.2e-75	247.1	COG0547	Anthranilate phosphoribosyltransferase	338
2904475942	724	98.53	12	706	2	669	0.0e+00	510.6	COG1199	Rad3-related DNA helicase	654
2904475943	369	100	1	369	1	360	5.9e-118	388.2	COG3203	Outer membrane protein (porin)	354
2904475945	268	94.22	1	268	17	277	4.0e-92	302.6	COG2503	Predicted secreted acid phosphatase	274
2904475946	279	97.29	18	272	2	252	5.7e-73	239.4	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
2904475947	360	98.21	22	360	5	333	2.1e-93	307.1	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2904475948	491	88.46	1	491	37	519	0.0e+00	694.9	COG0833	Amino acid permease	541
2904475949	290	97.67	3	290	1	294	5.5e-63	207.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904475950	368	97.9	20	364	7	333	1.0e-123	406.5	COG2855	Uncharacterized membrane protein YadS	334
2904475951	288	98.94	1	284	1	279	8.1e-105	344.2	COG0648	Endonuclease IV	280
2904475952	566	45.08	14	100	52	106	5.8e-50	19.3	COG1445	Phosphotransferase system fructose-specific component IIB	122
2904475952	566	92.62	104	223	2	114	5.8e-50	144.7	COG1445	Phosphotransferase system fructose-specific component IIB	122
2904475952	566	98.55	227	565	3	341	0.0e+00	449.7	COG1299	Phosphotransferase system, fructose-specific IIC component	343
2904475953	311	99.35	4	311	1	308	1.5e-120	396	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
2904475954	376	89.44	148	279	5	131	6.3e-66	19.3	COG4668	Mannitol/fructose-specific phosphotransferase system, IIA domain	142
2904475954	376	97.75	285	375	2	88	1.4e-31	99.1	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
2904475954	376	100	2	143	1	142	6.3e-66	193.5	COG4668	Mannitol/fructose-specific phosphotransferase system, IIA domain	142
2904475955	404	48.56	211	393	4	189	3.7e-19	30.7	COG0477	MFS family permease	338
2904475955	404	50.65	4	216	8	201	3.7e-19	40.4	COG0477	MFS family permease	338
2904475956	84	56.34	1	72	11	90	5.2e-06	20.7	COG0727	Fe-S-cluster containining protein	132
2904475957	190	98.47	1	133	3	131	9.4e-37	119.1	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
2904475958	489	99.58	10	487	3	474	0.0e+00	583.2	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
2904475959	243	94.61	1	227	10	237	2.2e-66	217.8	COG2186	DNA-binding transcriptional regulator, FadR family	241
2904475960	103	25.67	1	93	8	55	7.2e-05	16.8	COG3539	Pilin (type 1 fimbria component protein)	184
2904475961	324	95.4	2	323	2	312	4.4e-69	227.5	COG0523	GTPase, G3E family	323
2904475962	237	96.12	24	232	4	226	1.6e-21	71.2	COG0671	Membrane-associated phospholipid phosphatase	232
2904475963	150	47.79	15	144	131	249	5.0e-41	135.8	COG0791	Cell wall-associated hydrolase, NlpC family	197
2904475964	527	23.25	9	163	14	136	6.4e-77	10.4	COG4943	Environmental sensor c-di-GMP phosphodiesterase, contains periplasmic CSS-motif sensor and cytoplasmic EAL domain	524
2904475964	527	52.74	224	524	243	521	6.4e-77	241.6	COG4943	Environmental sensor c-di-GMP phosphodiesterase, contains periplasmic CSS-motif sensor and cytoplasmic EAL domain	524
2904475965	601	98.26	1	594	10	573	0.0e+00	496.4	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2904475966	364	99.45	1	364	2	363	0.0e+00	637.7	COG4174	ABC-type microcin C transport system, permease component YejB	364
2904475967	347	98.53	3	343	3	338	0.0e+00	549.3	COG4239	ABC-type microcin C transport system, permease component YejE	341
2904475968	540	98.88	5	536	4	531	0.0e+00	838.8	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
2904475971	551	97.36	8	551	6	558	1.3e-63	206.6	COG2303	Choline dehydrogenase or related flavoprotein	542
2904475972	467	27.44	2	101	42	86	6.9e-38	14.8	COG2010	Cytochrome c, mono- and diheme variants	150
2904475972	467	59.15	309	427	62	158	6.9e-38	46.9	COG2010	Cytochrome c, mono- and diheme variants	150
2904475972	467	98.78	106	281	1	162	6.9e-38	67.2	COG2010	Cytochrome c, mono- and diheme variants	150
2904475973	247	91.04	1	240	4	247	3.7e-54	178.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904475974	254	99.25	5	252	2	267	1.1e-68	225.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904475975	327	98.5	6	327	1	329	6.6e-81	266.3	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904475976	450	90.44	2	418	28	434	3.4e-38	125.7	COG2271	Sugar phosphate permease	448
2904475977	401	47.78	208	399	5	187	1.4e-36	13.6	COG0477	MFS family permease	338
2904475977	401	83.03	7	321	5	322	1.4e-36	114.1	COG0477	MFS family permease	338
2904475978	235	95.93	1	232	3	238	1.6e-76	250.8	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2904475979	587	92.61	2	479	36	486	7.4e-113	372.1	COG1061	Superfamily II DNA or RNA helicase	442
2904475980	96	97.85	1	96	3	93	1.0e-32	106.5	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
2904475981	334	99.1	1	334	1	332	0.0e+00	589	COG3081	Nucleoid-associated protein YejK (function unknown)	335
2904475982	75	100	1	74	1	74	6.0e-43	139.1	COG3082	Uncharacterized conserved protein YejL, UPF0352 family	74
2904475983	593	100	1	593	1	600	0.0e+00	853	COG3083	Membrane-anchored periplasmic protein YejM, alkaline phosphatase superfamily	600
2904475984	321	99.38	1	311	3	322	3.3e-123	405	COG0435	Glutathionyl-hydroquinone reductase	324
2904475986	590	99.05	4	563	4	629	6.6e-122	401.9	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2904475988	128	72.73	4	121	30	125	2.2e-25	83.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904475989	375	100	1	375	1	360	8.3e-115	377.8	COG3203	Outer membrane protein (porin)	354
2904475991	389	96.67	9	381	12	388	2.1e-40	133.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904475992	725	96.62	7	710	13	699	0.0e+00	643.4	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2904475993	458	91.09	13	443	31	449	1.4e-68	225.8	COG1538	Outer membrane protein TolC	457
2904475994	4599	56	711	780	29	84	1.1e-03	4.9	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
2904475995	897	54.4	779	887	20	87	1.2e-08	29.8	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2904475995	897	74.37	262	680	99	391	1.4e-26	85.2	COG0642	Signal transduction histidine kinase	336
2904475996	216	96.68	4	209	1	204	4.7e-50	164.2	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2904475997	930	62.09	797	927	9	121	2.6e-07	24.1	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2904475997	930	84.77	256	675	56	389	4.7e-75	247.1	COG0642	Signal transduction histidine kinase	336
2904475998	883	99.75	1	842	2	812	0.0e+00	1245	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
2904475999	240	97.95	1	240	4	242	1.7e-104	342.6	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2904476000	1225	99.7	604	1225	3	658	3.3e-81	268.2	COG3468	Type V secretory pathway, adhesin AidA	644
2904476002	760	99.08	58	758	2	757	0.0e+00	525	COG0209	Ribonucleotide reductase alpha subunit	696
2904476003	376	98.54	2	371	3	339	5.5e-104	342	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
2904476004	86	87.38	1	86	5	94	1.4e-20	67.3	COG0633	Ferredoxin	102
2904476005	401	95.72	1	394	1	246	1.3e-98	323.3	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
2904476007	477	95.41	1	477	13	490	0.0e+00	747.8	COG0753	Catalase	496
2904476008	457	95.42	4	455	17	558	2.2e-65	210.2	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2904476009	333	100	1	330	1	321	0.0e+00	495.1	COG1441	O-succinylbenzoate synthase	321
2904476010	285	98.94	6	285	3	281	0.0e+00	521.3	COG0447	1,4-Dihydroxy-2-naphthoyl-CoA synthase	282
2904476011	277	92.54	3	267	22	294	9.7e-32	105.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904476012	557	98.94	1	557	3	564	0.0e+00	692.4	COG1165	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase	566
2904476013	445	93.65	10	438	26	423	0.0e+00	441.5	COG1169	Isochorismate synthase EntC	423
2904476014	102	98.08	1	102	2	103	2.1e-35	116.1	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2904476016	486	98.53	4	486	3	471	0.0e+00	527.4	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
2904476017	509	98.59	1	508	4	494	0.0e+00	648.4	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
2904476018	615	99.68	4	611	2	616	0.0e+00	648.4	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2904476019	100	100	1	100	1	100	1.0e-41	135.3	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
2904476020	186	97.62	1	162	4	167	1.4e-51	168.8	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
2904476021	180	90.86	1	174	11	169	1.0e-54	179.1	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
2904476022	325	99.4	1	325	1	331	0.0e+00	454.1	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
2904476023	908	99.86	1	783	1	730	0.0e+00	885.1	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
2904476025	453	97.88	6	433	9	423	0.0e+00	639.7	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2904476026	178	94.58	14	178	7	163	2.0e-64	210.2	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2904476027	599	97.78	20	201	4	179	2.3e-57	187.8	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
2904476027	599	99.75	201	599	2	398	0.0e+00	558.1	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
2904476028	224	97.42	17	214	4	192	2.0e-83	272.6	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
2904476029	147	98.36	6	127	2	121	1.8e-42	138.5	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
2904476030	314	92.36	11	306	1	278	2.0e-53	176.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476031	404	99.49	8	403	3	396	6.5e-121	398.3	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2904476032	199	97.94	1	195	3	192	1.8e-61	202	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
2904476033	610	99.38	15	610	1	480	1.9e-130	429.9	COG0471	Di- and tricarboxylate transporter	461
2904476034	217	96.83	2	212	2	215	1.3e-50	166.7	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2904476035	164	97.62	1	164	5	168	2.1e-91	298.8	COG3013	Uncharacterized protein YfbU, UPF0304 family	168
2904476036	151	97.32	3	151	5	149	7.1e-74	241.2	COG3092	Uncharacterized membrane protein YfbV, UPF0208 family	149
2904476038	400	98.99	4	400	2	395	0.0e+00	560.8	COG0282	Acetate kinase	396
2904476039	719	40.81	379	561	215	365	0.0e+00	29.2	COG0857	BioD-like N-terminal domain of phosphotransacetylase	354
2904476039	719	98.65	1	380	2	366	0.0e+00	509	COG0857	BioD-like N-terminal domain of phosphotransacetylase	354
2904476040	317	99.04	7	317	3	311	4.2e-125	410.8	COG3958	Transketolase, C-terminal subunit	312
2904476041	277	97.94	1	240	6	243	9.6e-96	314	COG3959	Transketolase, N-terminal subunit	243
2904476042	458	97.93	1	458	3	475	0.0e+00	514.3	COG3037	Ascorbate-specific PTS system EIIC-type component UlaA	481
2904476043	96	97.85	3	92	2	92	6.8e-25	81.9	COG3414	Phosphotransferase system, galactitol-specific IIB component	93
2904476044	147	97.37	1	147	1	148	1.0e-36	120.3	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
2904476045	338	98.8	13	338	1	330	8.6e-92	302.3	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904476046	210	77.33	27	165	13	145	3.1e-15	50.6	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2904476047	209	97.67	1	209	1	210	1.1e-58	193	COG0625	Glutathione S-transferase	211
2904476048	298	98.99	3	298	1	294	2.2e-117	386	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
2904476049	531	93.08	4	531	35	572	0.0e+00	453.3	COG0747	ABC-type transport system, periplasmic component	556
2904476050	410	98.56	5	410	5	414	2.9e-112	369.8	COG2195	Di- or tripeptidase	414
2904476051	257	98.05	1	257	3	253	0.0e+00	479.3	COG4598	ABC-type histidine transport system, ATPase component	256
2904476052	237	96.49	7	234	8	227	1.1e-97	320.3	COG4160	ABC-type arginine/histidine transport system, permease component	228
2904476053	228	99.13	1	226	2	229	3.2e-96	315.4	COG4215	ABC-type arginine transport system, permease component	230
2904476054	260	94.35	1	260	10	276	1.2e-64	212.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904476055	190	98.43	1	190	2	189	2.7e-83	272.7	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
2904476056	505	98.72	1	485	4	467	0.0e+00	653.2	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
2904476057	163	88.46	1	163	1	161	3.5e-61	200.7	COG1286	Uncharacterized membrane protein, required for colicin V production	182
2904476058	257	99.16	1	255	2	237	2.8e-66	214.5	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
2904476059	428	98.6	7	425	2	424	0.0e+00	478.1	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
2904476060	304	97.96	1	292	1	288	0.0e+00	450.3	COG0777	Acetyl-CoA carboxylase beta subunit	294
2904476061	226	98.56	18	226	2	206	1.1e-67	221.8	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2904476062	276	94.01	14	274	3	253	4.7e-87	285.9	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
2904476063	336	99.7	4	331	2	336	7.2e-99	325.7	COG0136	Aspartate-semialdehyde dehydrogenase	334
2904476064	377	94.79	1	297	4	312	3.0e-73	238.2	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2904476065	234	79.55	95	234	21	125	5.3e-24	78.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904476066	298	95.68	1	294	9	296	8.4e-43	141.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2904476068	150	83.33	26	134	19	113	4.8e-14	46.6	COG0607	Rhodanese-related sulfurtransferase	110
2904476069	495	97.15	24	491	6	448	4.8e-130	428.7	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2904476070	357	87.74	1	356	32	403	7.9e-46	150.6	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
2904476071	490	98.19	15	483	3	437	3.0e-68	224.9	COG3182	Uncharacterized iron-regulated membrane protein	442
2904476073	406	99.28	1	403	2	412	0.0e+00	455.6	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2904476074	676	95.36	263	665	7	376	8.5e-50	164	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2904476074	676	96.46	1	253	2	246	9.1e-96	314	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
2904476076	185	96.11	6	184	3	175	3.6e-98	320.5	COG3101	Elongation factor P hydroxylase (EF-P beta-lysylation pathway)	180
2904476077	266	98.07	6	257	4	257	5.4e-61	200.4	COG0730	Uncharacterized membrane protein YfcA	258
2904476078	283	96.13	9	283	6	278	4.0e-127	417.3	COG3770	Murein endopeptidase	284
2904476079	361	97.3	2	361	2	361	0.0e+00	543	COG0082	Chorismate synthase	369
2904476080	310	97.91	14	301	2	282	7.0e-75	246.1	COG2890	Methylase of polypeptide chain release factors	280
2904476081	179	97.83	1	177	1	180	1.6e-66	218.3	COG2840	DNA-nicking endonuclease, Smr domain	184
2904476082	162	97.55	1	160	2	160	5.5e-47	153.9	COG2062	Phosphohistidine phosphatase SixA	163
2904476083	733	17.63	661	728	220	277	6.8e-114	12.6	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2904476083	733	91.7	19	305	12	254	5.4e-63	206.5	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2904476083	733	99.39	321	661	3	329	6.8e-114	360.3	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2904476084	437	99.49	12	436	2	393	1.7e-113	374	COG0183	Acetyl-CoA acetyltransferase	392
2904476085	110	96.94	14	110	4	98	1.0e-45	148.7	COG3691	Uncharacterized conserved protein YfcZ, UPF0381/DUF406 family	98
2904476086	425	99.77	3	425	2	444	0.0e+00	492.1	COG2067	Long-chain fatty acid transport protein	440
2904476087	255	97.61	1	255	6	250	1.4e-93	307.1	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
2904476088	404	97.23	2	294	3	283	2.0e-77	254.4	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
2904476089	161	95.42	1	156	6	151	8.4e-55	178.7	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
2904476090	183	90.67	12	159	13	148	1.2e-14	49.1	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2904476091	657	99.85	1	649	1	645	0.0e+00	944.5	COG1138	Cytochrome c biogenesis factor	648
2904476092	164	95.42	1	159	2	147	4.8e-63	205.6	COG2332	Cytochrome c-type biogenesis protein CcmE	153
2904476093	86	95.52	3	69	1	64	2.5e-33	108.4	COG3114	Heme exporter protein D	67
2904476094	245	84.75	1	243	36	274	4.5e-75	247.1	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
2904476095	219	98.64	1	219	3	220	1.2e-94	310.4	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
2904476096	213	97.13	1	212	3	205	2.8e-86	282.8	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
2904476097	305	97.36	26	286	7	264	9.8e-64	209	COG2116	Formate/nitrite transporter FocA, FNT family	265
2904476099	392	92.24	83	386	11	319	4.9e-46	151.7	COG0582	Integrase	309
2904476104	894	84.97	2	338	4	314	1.5e-87	287.9	COG4643	Uncharacterized domain associated with phage/plasmid primase	366
2904476104	894	92.04	332	893	38	569	1.0e-114	378.2	COG5519	Uncharcterized protein, DUF927 family	562
2904476113	72	85.71	4	72	9	68	2.0e-25	81.8	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2904476115	272	98.52	5	272	5	270	2.2e-103	339.4	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
2904476116	175	98.22	1	168	2	167	2.2e-52	171.7	COG1247	L-amino acid N-acyltransferase YncA	169
2904476117	512	96.77	1	480	5	454	4.8e-102	336.2	COG2211	Na+/melibiose symporter or related transporter	467
2904476118	341	99.72	2	341	1	350	7.2e-69	227.2	COG0673	Predicted dehydrogenase	342
2904476119	355	70.09	24	351	24	269	2.7e-30	100.2	COG0673	Predicted dehydrogenase	342
2904476120	391	98.86	1	346	3	349	9.3e-80	263	COG0673	Predicted dehydrogenase	342
2904476122	353	99.1	5	342	2	332	6.9e-57	187.5	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904476123	281	96.28	43	264	3	209	1.9e-48	159.4	COG0625	Glutathione S-transferase	211
2904476124	301	98.73	69	296	2	235	7.7e-67	219.5	COG0412	Dienelactone hydrolase	236
2904476127	293	95.02	8	292	2	287	1.7e-48	160.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476128	107	75.81	3	106	18	111	1.8e-28	93.5	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2904476129	135	53.62	1	48	1	37	6.7e-06	3.2	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2904476129	135	55.07	72	134	17	54	6.7e-06	15.2	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2904476131	695	32	1	181	32	207	0.0e+00	27	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2904476131	695	94.36	165	695	28	546	0.0e+00	617.3	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2904476132	340	99.41	6	340	3	339	1.3e-115	380.1	COG0309	Hydrogenase maturation factor	339
2904476133	390	99.73	1	370	1	366	0.0e+00	522.5	COG0409	Hydrogenase maturation factor	364
2904476134	92	91.46	1	84	1	75	8.1e-29	93.8	COG0298	Hydrogenase maturation factor	82
2904476135	259	97.47	59	259	5	197	2.1e-68	223.8	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
2904476136	114	98.26	1	114	1	113	2.6e-38	125.1	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
2904476138	209	94.01	7	196	1	157	7.7e-53	172.7	COG1142	Fe-S-cluster-containing hydrogenase component 2	165
2904476139	634	97.63	9	542	3	496	5.4e-104	342.6	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
2904476140	317	97.09	11	315	10	309	2.4e-94	310.1	COG0650	Formate hydrogenlyase subunit 4	309
2904476141	574	96.97	10	173	6	165	5.7e-71	231.4	COG3262	Ni,Fe-hydrogenase III component G	165
2904476141	574	98.95	178	558	3	378	0.0e+00	527.8	COG3261	Ni,Fe-hydrogenase III large subunit	382
2904476142	185	74.29	1	152	21	150	5.2e-39	127.8	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
2904476143	265	96.62	31	178	3	145	1.8e-67	219.5	COG3260	Ni,Fe-hydrogenase III small subunit	148
2904476145	161	90.62	5	156	3	147	4.5e-38	125.3	COG0680	Ni,Fe-hydrogenase maturation factor	160
2904476146	181	95.21	1	178	1	159	3.7e-57	186.8	COG1142	Fe-S-cluster-containing hydrogenase component 2	165
2904476147	723	69.63	1	718	261	941	0.0e+00	719.6	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2904476148	775	99.34	6	763	3	749	0.0e+00	853.7	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
2904476149	341	95.03	2	338	15	339	0.0e+00	448.7	COG3376	High-affinity nickel permease	342
2904476153	216	90.52	10	215	17	207	4.7e-31	102.3	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2904476156	277	95.29	1	270	1	243	1.3e-81	268.3	COG1462	Curli biogenesis system outer membrane secretion channel CsgG	252
2904476157	152	29.41	3	129	5	44	1.2e-05	16.9	COG3631	Ketosteroid isomerase-related protein	133
2904476159	174	97.24	1	174	4	179	8.7e-57	186.1	COG3038	Cytochrome b561	181
2904476160	208	86.03	1	204	25	178	1.4e-44	146.2	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
2904476161	280	76.52	162	280	23	123	3.7e-21	69.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904476162	419	98.23	11	397	5	393	9.4e-129	424.1	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2904476163	179	94.12	2	179	9	184	3.4e-36	119.4	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2904476164	577	98.92	4	569	1	551	0.0e+00	656.3	COG3275	Sensor histidine kinase, LytS/YehU family	557
2904476165	256	98.39	1	256	3	246	2.7e-73	241.2	COG3279	DNA-binding response regulator, LytR/AlgR family	244
2904476166	323	98.44	1	316	5	319	0.0e+00	457.4	COG0837	Glucokinase	320
2904476167	420	91.01	1	414	10	414	1.3e-49	163.4	COG0038	H+/Cl- antiporter ClcA	443
2904476168	232	99.57	1	231	1	229	1.7e-98	323.3	COG1794	Aspartate/glutamate racemase	230
2904476169	157	95.97	5	153	4	146	3.6e-63	206.3	COG4125	Uncharacterized membrane protein	149
2904476170	295	96.01	4	286	4	292	6.7e-59	194.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476171	552	99.46	2	552	2	556	0.0e+00	679.6	COG3961	TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase	557
2904476172	329	97.19	13	329	1	311	2.2e-100	330	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2904476174	409	97.86	3	409	5	415	0.0e+00	449.2	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
2904476175	395	99.51	2	395	2	404	0.0e+00	500.6	COG1972	Nucleoside permease NupC	404
2904476178	263	96.23	1	257	5	259	1.1e-79	261.3	COG2116	Formate/nitrite transporter FocA, FNT family	265
2904476179	472	97.92	1	463	9	478	0.0e+00	546.2	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2904476184	269	81.29	1	251	55	293	4.8e-79	260	COG4302	Ethanolamine ammonia-lyase, small subunit	294
2904476185	460	97.35	1	453	3	443	0.0e+00	706	COG4303	Ethanolamine ammonia-lyase, large subunit	453
2904476186	469	91.87	2	464	9	460	1.8e-72	238.7	COG0531	Amino acid transporter	466
2904476187	186	97.85	2	183	4	185	1.4e-64	211.2	COG3575	Uncharacterized protein	184
2904476188	113	11.04	16	102	22	91	2.9e-04	13.5	COG5280	Phage-related minor tail protein	634
2904476189	308	97.67	3	298	2	295	8.0e-68	223.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476190	329	96.91	1	326	6	319	9.4e-109	357.8	COG0385	Predicted Na+-dependent transporter	319
2904476191	80	98.59	1	72	1	70	8.7e-40	129.1	COG3530	Uncharacterized conserved protein, DUF3820 family	71
2904476192	673	99.26	1	672	5	673	0.0e+00	973	COG0272	NAD-dependent DNA ligase	667
2904476193	332	99.38	2	332	1	322	3.9e-109	359.7	COG3115	Cell division protein ZipA, interacts with FtsZ	324
2904476195	266	95.6	5	253	5	243	9.4e-109	357.1	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
2904476196	321	99.01	4	308	3	301	3.6e-121	398.2	COG0031	Cysteine synthase	300
2904476197	85	94.38	1	85	1	84	3.8e-36	117.5	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
2904476198	575	99.65	1	573	2	573	0.0e+00	830.4	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
2904476199	169	97.44	16	169	4	155	5.2e-63	205.7	COG2190	Phosphotransferase system IIA component	156
2904476200	449	79.44	108	449	76	388	4.1e-54	178.9	COG0642	Signal transduction histidine kinase	336
2904476201	227	98.71	1	227	1	229	1.1e-78	258.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904476202	294	98.34	1	290	5	301	5.8e-110	361.4	COG0031	Cysteine synthase	300
2904476203	364	98.57	1	352	1	345	0.0e+00	472.5	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
2904476204	291	94.43	2	289	12	282	0.0e+00	435.4	COG4208	ABC-type sulfate transport system, permease component	287
2904476205	276	98.18	1	274	4	272	1.8e-108	355.9	COG0555	ABC-type sulfate transport system, permease component	274
2904476206	340	95.6	1	338	15	340	0.0e+00	589.3	COG4150	ABC-type sulfate transport system, periplasmic component	341
2904476207	299	90.98	1	299	22	354	2.2e-94	310.9	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
2904476210	133	100	2	133	1	128	6.7e-50	162.9	COG3111	Predicted periplasmic protein YdeI with OB-fold, BOF family	128
2904476211	141	64.02	2	130	43	163	3.4e-23	76.7	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2904476212	294	78.2	9	286	57	264	5.5e-73	240	COG0860	N-acetylmuramoyl-L-alanine amidase	231
2904476213	316	98.68	2	304	5	303	0.0e+00	502.1	COG0408	Coproporphyrinogen III oxidase	303
2904476214	149	98	1	149	2	148	1.0e-61	201.6	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
2904476215	315	98.72	1	311	3	311	1.4e-120	396.7	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
2904476216	759	96.61	1	433	15	441	0.0e+00	597.8	COG0281	Malic enzyme	432
2904476216	759	99.69	430	758	1	326	1.3e-124	409.7	COG0280	Phosphotransacetylase	327
2904476217	316	99.34	4	314	2	303	1.1e-109	361.1	COG0176	Transaldolase	239
2904476218	664	99.25	1	664	5	662	0.0e+00	1045	COG0021	Transketolase	663
2904476219	451	71.45	1	451	7	439	3.5e-80	264.4	COG0443	Molecular chaperone DnaK (HSP70)	579
2904476220	318	97.5	2	317	1	312	1.1e-100	330.9	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2904476221	491	48.83	271	481	5	191	3.3e-38	18.9	COG0477	MFS family permease	338
2904476221	491	98.96	20	331	2	380	3.3e-38	113.8	COG0477	MFS family permease	338
2904476222	461	85.28	38	459	56	391	1.7e-64	213.1	COG0642	Signal transduction histidine kinase	336
2904476223	239	98.71	12	235	2	230	2.8e-77	253.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904476224	115	93.22	54	111	4	58	1.9e-44	59.5	COG3422	Uncharacterized conserved protein YegP, UPF0339 family	59
2904476224	115	96.61	2	60	3	59	1.9e-44	90.4	COG3422	Uncharacterized conserved protein YegP, UPF0339 family	59
2904476225	461	98.86	5	397	5	350	0.0e+00	518.5	COG0826	Collagenase-like protease, PrtC family	347
2904476227	295	97.68	1	294	6	300	2.5e-84	277.1	COG1597	Diacylglycerol kinase family enzyme	301
2904476228	520	97.42	3	476	4	456	1.9e-108	357.1	COG2211	Na+/melibiose symporter or related transporter	467
2904476229	337	96.56	1	337	5	341	8.4e-97	318.6	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
2904476230	404	98.39	1	389	4	370	8.4e-116	381.1	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2904476231	337	100	1	337	1	353	8.3e-93	305.2	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2904476232	429	92.44	1	425	22	437	1.5e-44	146.9	COG2271	Sugar phosphate permease	448
2904476233	184	25.74	110	144	7	32	1.1e-22	13.6	COG1605	Chorismate mutase	101
2904476233	184	76.24	26	106	24	100	1.1e-22	59	COG1605	Chorismate mutase	101
2904476234	657	98.58	4	657	7	632	0.0e+00	876.1	COG3533	Uncharacterized conserved protein, DUF1680 family	589
2904476235	469	96.56	20	469	5	453	5.8e-130	428.2	COG2211	Na+/melibiose symporter or related transporter	467
2904476236	278	75.76	154	276	26	125	1.6e-21	70.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904476237	228	92.67	1	225	12	226	5.0e-63	207	COG1802	DNA-binding transcriptional regulator, GntR family	230
2904476239	266	99.24	1	266	2	262	1.4e-102	336.8	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
2904476240	269	94.72	11	268	4	254	1.2e-93	307.5	COG2145	Hydroxyethylthiazole kinase, sugar kinase family	265
2904476242	339	77.16	5	288	9	285	1.2e-22	75.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2904476243	212	36.89	19	183	63	152	2.2e-13	44.1	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2904476244	302	91.36	5	298	21	316	8.3e-08	21.4	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2904476245	590	41.13	9	435	61	285	2.0e-07	21.1	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
2904476246	144	73.46	6	137	34	152	3.3e-10	34.9	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904476248	297	97.34	7	297	1	293	2.7e-47	156.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476249	257	98.95	1	220	1	189	2.1e-68	224.2	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
2904476250	444	90.71	269	444	9	174	3.0e-54	177.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904476251	525	98.99	7	206	2	197	5.2e-79	258.7	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2904476251	525	99.68	207	525	2	316	0.0e+00	514.9	COG0519	GMP synthase, PP-ATPase domain/subunit	315
2904476252	488	94.04	1	211	7	211	2.4e-122	175.2	COG0516	IMP dehydrogenase/GMP reductase	170
2904476252	488	99.54	257	476	1	217	2.4e-122	231.5	COG0516	IMP dehydrogenase/GMP reductase	170
2904476253	457	98.43	5	449	4	441	0.0e+00	590.9	COG1570	Exonuclease VII, large subunit	440
2904476254	787	92.98	17	786	44	772	0.0e+00	657.1	COG1501	Alpha-glucosidase, glycosyl hydrolase family GH31	772
2904476255	437	93.78	4	436	22	443	4.9e-35	115.4	COG2271	Sugar phosphate permease	448
2904476256	360	99.1	5	342	2	332	3.3e-62	205	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904476257	344	53.8	19	344	237	512	3.9e-104	344	COG3227	Zn-dependent metalloprotease	507
2904476259	76	16.67	24	47	14	22	2.6e-03	3.5	COG4338	Uncharacterized protein	54
2904476259	76	25.93	1	24	12	25	2.6e-03	12.1	COG4338	Uncharacterized protein	54
2904476260	318	98.72	5	315	3	311	2.4e-61	201.9	COG0679	Predicted permease	311
2904476261	494	99.55	1	470	2	444	0.0e+00	619.1	COG1160	Predicted GTPases	444
2904476262	393	96.97	1	392	10	393	1.2e-74	245.9	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
2904476263	206	99.04	1	206	2	207	4.3e-71	233.3	COG2976	Putative negative regulator of RcsB-dependent stress response	207
2904476264	424	98.84	2	423	2	428	0.0e+00	502.6	COG0124	Histidyl-tRNA synthetase	429
2904476265	373	98.92	7	366	2	367	0.0e+00	492.9	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
2904476266	330	99.66	12	296	2	291	1.2e-72	239.1	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
2904476267	253	96.4	6	252	10	250	3.3e-83	273.4	COG3063	Tfp pilus assembly protein PilF	250
2904476268	399	99.71	31	382	1	348	0.0e+00	503.5	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
2904476269	141	98.52	2	136	2	134	2.6e-60	196.5	COG0105	Nucleoside diphosphate kinase	135
2904476271	436	67.97	25	436	155	485	0.0e+00	465.1	COG0260	Leucyl aminopeptidase	485
2904476272	389	98.7	3	388	2	382	0.0e+00	555.1	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
2904476273	164	90.67	1	149	1	136	9.6e-52	169.3	COG1959	DNA-binding transcriptional regulator, IscR family	150
2904476274	245	97.18	1	245	1	241	3.6e-96	315.9	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
2904476275	267	99.23	1	258	1	257	1.5e-93	307.2	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2904476276	339	97.76	14	326	3	308	1.9e-88	290.9	COG2215	ABC-type nickel/cobalt efflux system, permease component RcnA	303
2904476277	223	95.37	10	222	11	216	3.1e-71	233.8	COG3683	ABC-type uncharacterized transport system, periplasmic component	213
2904476278	426	10.4	9	108	74	125	5.2e-36	4.5	COG3711	Transcriptional antiterminator	491
2904476278	426	35	173	418	252	426	5.2e-36	112.6	COG3711	Transcriptional antiterminator	491
2904476279	386	50.65	202	386	9	202	3.2e-06	10.9	COG0477	MFS family permease	338
2904476279	386	83.03	3	318	2	319	3.2e-06	12.5	COG0477	MFS family permease	338
2904476280	417	98.8	2	417	5	414	0.0e+00	656.6	COG0112	Glycine/serine hydroxymethyltransferase	413
2904476281	396	87.69	148	395	1	235	1.1e-73	240.9	COG1018	Ferredoxin-NADP reductase	266
2904476281	396	99.33	1	148	1	149	4.2e-65	212.7	COG1017	Hemoglobin-like flavoprotein	150
2904476283	419	35.98	7	108	33	91	5.7e-32	13	COG2010	Cytochrome c, mono- and diheme variants	150
2904476283	419	48.17	293	408	56	134	5.7e-32	29.2	COG2010	Cytochrome c, mono- and diheme variants	150
2904476283	419	98.78	116	291	1	162	5.7e-32	68	COG2010	Cytochrome c, mono- and diheme variants	150
2904476284	533	97.36	1	532	6	558	6.4e-74	243	COG2303	Choline dehydrogenase or related flavoprotein	542
2904476286	112	100	1	112	1	112	8.4e-52	168.8	COG0347	Nitrogen regulatory protein PII	112
2904476287	445	99.14	3	445	3	465	0.0e+00	562	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904476289	479	85.28	67	479	56	391	3.9e-63	208.8	COG0642	Signal transduction histidine kinase	336
2904476293	648	97.63	7	616	5	621	0.0e+00	528	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2904476295	258	93.56	4	256	17	292	6.3e-31	101.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904476296	416	50.91	224	410	9	203	2.1e-20	30.6	COG0477	MFS family permease	338
2904476296	416	57.96	11	252	4	225	2.1e-20	40.9	COG0477	MFS family permease	338
2904476298	448	99.2	5	418	2	371	5.8e-75	246.7	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2904476299	445	50.91	236	439	8	202	2.5e-25	20.6	COG0477	MFS family permease	338
2904476299	445	59.53	13	278	6	233	2.5e-25	67.8	COG0477	MFS family permease	338
2904476303	70	98.51	4	70	1	66	2.4e-35	114.8	COG1278	Cold shock protein, CspA family	67
2904476307	520	94.54	347	519	8	180	1.2e-53	175	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904476308	159	70.77	1	142	4	95	2.1e-14	48.9	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2904476309	163	60.13	38	154	38	129	1.8e-14	47.7	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
2904476310	302	98.01	2	294	2	296	1.5e-75	249	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476311	364	84.65	2	363	34	375	1.8e-65	215.9	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2904476312	414	96.96	2	389	7	389	1.3e-94	311.2	COG2814	Predicted arabinose efflux permease, MFS family	394
2904476314	35	21.09	2	32	2	28	2.4e-02	9.3	COG4578	DNA-binding transcriptional regulator of glucitol operon	128
2904476316	684	87.92	6	683	80	727	2.9e-115	380.1	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
2904476317	1227	99.74	1	1193	4	1152	0.0e+00	837.8	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2904476318	1152	99.72	4	1149	2	1077	0.0e+00	1029.7	COG1330	Exonuclease V gamma subunit	1078
2904476320	365	92.84	1	362	3	339	1.9e-106	350.7	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2904476321	300	98.01	7	300	1	295	6.3e-51	168.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476322	101	93.94	1	98	4	96	1.5e-48	157.3	COG3526	Predicted selenoprotein, Rdx family	99
2904476323	286	93.67	3	286	1	296	2.1e-50	165.9	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2904476324	285	98.58	4	284	4	281	3.4e-74	243.8	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2904476325	323	96.24	14	323	7	313	4.0e-105	345.6	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2904476326	497	98.8	1	495	5	499	0.0e+00	616.4	COG1129	ABC-type sugar transport system, ATPase component	500
2904476327	348	91.74	1	339	27	326	3.6e-73	240.6	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2904476328	326	71.63	3	325	70	377	3.4e-22	73.1	COG4952	L-rhamnose isomerase	430
2904476329	595	88.24	139	595	51	425	2.0e-103	341.1	COG0840	Methyl-accepting chemotaxis protein	408
2904476330	260	81.58	10	208	32	186	5.8e-32	104.7	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2904476331	385	96.44	2	385	12	390	5.8e-123	405.1	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2904476332	504	80.94	52	489	78	421	4.9e-89	293.8	COG0840	Methyl-accepting chemotaxis protein	408
2904476333	77	86.21	1	77	10	84	2.1e-19	64.1	COG3042	Putative hemolysin	85
2904476337	283	98.23	1	275	4	280	3.5e-106	348.5	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2904476338	119	32.5	1	117	1	104	5.3e-37	121.8	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2904476339	297	96.68	4	296	2	292	1.9e-70	232.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476341	64	3.93	2	62	653	680	1.6e-03	11.3	COG1328	Anaerobic ribonucleoside-triphosphate reductase	700
2904476343	509	68.71	193	451	4	227	1.6e-32	107.1	COG5529	Pyocin large subunit	326
2904476343	509	71	4	99	17	87	3.0e-10	34.7	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
2904476350	325	91.53	12	322	23	292	6.5e-28	92.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904476351	292	76.54	28	291	26	224	1.5e-27	91	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2904476352	297	98.01	2	297	2	296	3.0e-74	244.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476353	417	98.8	1	417	5	416	0.0e+00	602.8	COG0014	Gamma-glutamyl phosphate reductase	417
2904476354	367	98.65	1	367	5	369	0.0e+00	488.7	COG0263	Glutamate 5-kinase	369
2904476356	416	92.21	54	412	2	285	2.8e-29	96.6	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
2904476357	152	91.06	1	144	15	177	4.1e-31	102	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
2904476358	486	99.76	6	485	1	415	0.0e+00	489.1	COG2195	Di- or tripeptidase	414
2904476359	352	97.06	2	349	1	363	2.5e-111	366.7	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2904476360	241	75.67	1	240	14	240	1.9e-82	271.3	COG3034	Murein L,D-transpeptidase YafK	298
2904476361	255	97.66	1	255	1	250	7.5e-95	311.7	COG0121	Predicted glutamine amidotransferase	252
2904476362	193	99.44	2	179	2	177	9.4e-79	257.6	COG0279	Phosphoheptose isomerase	176
2904476363	822	18.8	481	617	323	397	1.6e-90	26.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2904476363	822	94.74	80	500	4	381	1.6e-90	276.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2904476365	156	100	1	155	1	155	1.1e-69	227.5	COG4807	Uncharacterized conserved protein YehS, DUF1456 family	155
2904476366	399	92.4	4	398	29	405	5.0e-123	405.2	COG4857	5-Methylthioribose kinase, methionine salvage pathway	408
2904476367	342	95.09	4	339	9	337	9.6e-116	380.7	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
2904476368	181	95.58	1	181	1	173	2.6e-61	200.7	COG1791	Acireductone dioxygenase (methionine salvage), cupin superfamily	181
2904476369	228	96.07	1	226	3	222	1.1e-81	268.2	COG4229	Enolase-phosphatase E1 involved in merthionine salvage	229
2904476370	204	82.14	2	204	12	195	3.5e-41	135.5	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2904476371	386	96.21	9	386	10	390	7.0e-104	342.2	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2904476372	257	96.4	2	257	2	269	6.2e-57	187.1	COG0388	Predicted amidohydrolase	274
2904476373	168	86.53	1	168	26	192	4.9e-62	203.5	COG3812	Uncharacterized protein	193
2904476374	422	60.25	166	399	93	239	2.0e-09	29.2	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
2904476375	111	93.55	1	111	9	124	1.7e-33	109.8	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
2904476376	164	93.18	1	164	8	171	7.4e-20	66	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
2904476377	424	97.37	14	422	11	417	2.9e-45	149.4	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2904476378	412	98.43	9	410	5	381	9.1e-119	391.1	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
2904476379	250	99.17	2	242	2	241	5.4e-108	354	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2904476380	217	93.42	1	216	13	225	1.7e-64	212	COG0765	ABC-type amino acid transport system, permease component	222
2904476381	221	92.98	1	219	13	224	1.1e-65	215.7	COG0765	ABC-type amino acid transport system, permease component	222
2904476382	263	96.47	1	261	3	275	3.1e-49	162.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904476383	279	98.58	1	275	3	280	2.9e-56	185	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2904476384	528	96.33	3	528	20	544	0.0e+00	469	COG0405	Gamma-glutamyltranspeptidase	539
2904476385	64	43.75	11	62	8	49	2.4e-03	12.6	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
2904476386	467	97.71	1	462	4	473	2.0e-125	413.8	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2904476388	312	94.4	12	310	14	266	1.1e-45	150.3	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2904476389	252	99.13	5	233	3	230	6.8e-78	255.5	COG4126	Asp/Glu/hydantoin racemase	230
2904476390	244	88.79	13	226	17	222	7.2e-49	160.5	COG1802	DNA-binding transcriptional regulator, GntR family	230
2904476391	500	93.43	3	495	22	490	0.0e+00	523.2	COG1953	Cytosine/uracil/thiamine/allantoin permease	497
2904476393	245	92.91	1	245	16	251	2.1e-63	209	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2904476394	361	98.27	1	361	6	345	0.0e+00	453.5	COG2957	Agmatine/peptidylarginine deiminase	346
2904476395	294	97.12	2	288	2	271	4.5e-74	243.2	COG0388	Predicted amidohydrolase	274
2904476396	155	94.87	2	152	2	149	9.1e-64	208.4	COG0328	Ribonuclease HI	154
2904476397	241	36.56	9	229	110	211	7.0e-08	27.5	COG0500	SAM-dependent methyltransferase	257
2904476398	251	91.92	1	222	20	258	3.4e-48	158.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2904476399	351	30.61	298	351	90	134	3.0e-22	33.7	COG1388	LysM repeat	124
2904476399	351	37.41	162	298	88	142	3.0e-22	40.1	COG1388	LysM repeat	124
2904476400	259	84.52	1	255	48	309	2.2e-80	264.6	COG3021	Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily	309
2904476401	391	97.22	1	388	10	393	0.0e+00	440.7	COG2814	Predicted arabinose efflux permease, MFS family	394
2904476402	298	97.34	4	298	5	297	1.0e-66	220	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476403	267	94.33	1	267	13	278	7.9e-96	314.6	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2904476404	228	80.27	3	208	18	196	6.9e-33	108	COG2091	Phosphopantetheinyl transferase	223
2904476405	409	99.52	1	409	2	413	1.7e-123	406.8	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2904476406	243	98.51	1	243	4	267	1.9e-62	205.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904476407	159	91.93	1	156	9	156	1.0e-36	120.6	COG4706	Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain	161
2904476408	390	98.07	1	390	8	413	4.9e-85	280.1	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2904476410	768	97.97	2	767	16	787	0.0e+00	759.6	COG4258	Predicted exporter	788
2904476411	201	84.98	1	195	12	192	2.6e-06	21.4	COG2834	Outer membrane lipoprotein-sorting protein	211
2904476412	147	90.65	11	145	5	130	6.3e-36	117.7	COG0824	Acyl-CoA thioesterase FadM	137
2904476413	573	97.41	253	570	3	303	6.9e-114	374	COG4261	Predicted acyltransferase, LPLAT superfamily	309
2904476414	114	62.84	7	112	37	129	3.7e-13	43.7	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2904476415	459	14.49	11	107	17	96	5.1e-40	6.6	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2904476415	459	20.11	324	459	431	541	5.1e-40	46	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2904476415	459	33.88	126	317	182	368	5.1e-40	75.6	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2904476416	175	87.06	1	175	15	189	5.7e-48	157.8	COG4648	Uncharacterized membrane protein	201
2904476417	84	98.77	1	80	1	80	6.3e-21	68.8	COG0236	Acyl carrier protein	80
2904476418	85	92.59	1	85	5	79	6.3e-19	62.4	COG0236	Acyl carrier protein	80
2904476419	270	87.36	32	269	12	239	2.8e-27	89.7	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2904476426	67	26.55	16	67	81	110	9.0e-04	13.4	COG3952	Uncharacterized N-terminal domain of lipid-A-disaccharide synthase	113
2904476427	180	97.37	20	179	4	151	1.7e-49	161.7	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
2904476431	505	70.59	1	498	129	584	0.0e+00	592.6	COG5525	Phage terminase, large subunit GpA	611
2904476432	455	82.99	141	437	46	323	5.1e-22	72.9	COG0582	Integrase	309
2904476433	78	74.29	10	77	11	62	3.0e-17	56.5	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2904476435	63	30.63	3	57	69	102	1.1e-06	22.3	COG4226	Predicted nuclease of the RNAse H fold, HicB family	111
2904476441	237	74.24	13	137	10	107	6.2e-06	20	COG2250	HEPN domain	132
2904476443	646	90.5	1	184	17	197	2.8e-53	174.7	COG0740	ATP-dependent protease ClpP, protease subunit	200
2904476444	154	43.68	4	154	84	159	2.5e-04	14	COG4220	Phage DNA packaging protein, Nu1 subunit of terminase	174
2904476447	492	97.43	5	492	2	493	0.0e+00	626.5	COG5511	Bacteriophage capsid protein	492
2904476448	676	87.5	11	202	25	199	6.7e-57	186.4	COG0740	ATP-dependent protease ClpP, protease subunit	200
2904476449	108	99.07	1	108	1	106	2.8e-31	102.1	COG5471	Predicted phage recombinase, RecA/RadA family	107
2904476453	245	72.06	1	245	24	268	6.8e-50	164.4	COG5492	Uncharacterized conserved protein YjdB, contains Ig-like domain	329
2904476456	776	22	1	218	21	218	2.5e-110	88.4	COG5281	Phage-related minor tail protein	833
2904476456	776	45.78	279	765	444	855	2.5e-110	282.1	COG5281	Phage-related minor tail protein	833
2904476458	113	99.1	1	112	1	110	1.3e-25	84	COG4718	Phage-related protein	111
2904476459	245	95.24	1	245	9	228	3.2e-65	213.9	COG4672	Phage-related protein	231
2904476460	239	89.63	1	127	5	125	2.5e-21	70.3	COG1310	Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif	134
2904476461	205	97.51	1	205	5	200	8.2e-58	189.5	COG4723	Phage-related protein, tail component	198
2904476462	1205	94.04	11	1120	2	1026	0.0e+00	931.1	COG4733	Phage-related protein, tail component	952
2904476465	334	92.71	1	333	3	320	5.5e-32	105.7	COG3594	Fucose 4-O-acetylase or related acetyltransferase	343
2904476466	202	66.81	1	161	59	213	4.9e-12	38	COG0671	Membrane-associated phospholipid phosphatase	232
2904476470	63	70	1	57	16	64	1.1e-04	15.3	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2904476472	167	45.28	1	167	198	360	2.1e-55	182.6	COG3203	Outer membrane protein (porin)	354
2904476473	161	89.33	1	153	4	137	1.2e-19	65.1	COG1959	DNA-binding transcriptional regulator, IscR family	150
2904476474	1050	99.8	2	1037	2	1013	0.0e+00	1145.1	COG0841	Multidrug efflux pump subunit AcrB	1009
2904476475	407	93.08	12	390	13	375	3.0e-64	211.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904476476	118	76.52	2	112	25	125	1.4e-30	100.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904476477	253	99.25	6	252	2	267	5.4e-68	223.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904476478	212	98.68	1	159	1	149	1.6e-40	132.4	COG0698	Ribose 5-phosphate isomerase RpiB	151
2904476479	106	72.52	2	106	30	124	9.6e-21	68.4	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2904476480	393	11.42	322	389	266	314	1.5e-43	20.1	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2904476480	393	12.82	13	116	247	301	1.5e-43	38.4	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2904476480	393	53.38	103	355	169	397	1.5e-43	86.9	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2904476481	500	49.35	256	466	8	196	2.8e-44	47.2	COG0477	MFS family permease	338
2904476481	500	75.46	23	291	4	292	2.8e-44	106.7	COG0477	MFS family permease	338
2904476482	493	82.59	10	492	26	452	1.1e-40	128.4	COG0366	Glycosidase	505
2904476485	561	97.03	1	559	7	594	0.0e+00	479.9	COG0443	Molecular chaperone DnaK (HSP70)	579
2904476486	178	70.33	1	176	26	172	4.0e-15	51.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904476487	226	92.86	14	226	10	191	4.9e-41	134.9	COG0693	Putative intracellular protease/amidase	188
2904476488	349	99.26	41	349	2	268	2.8e-102	335.9	COG1830	Fructose-bisphosphate aldolase class Ia, DhnA family	265
2904476489	791	99.27	11	791	5	819	0.0e+00	755.3	COG4458	Uncharacterized protein	821
2904476490	990	99.9	1	990	1	1013	0.0e+00	1502.4	COG4457	Uncharacterized protein	1014
2904476493	296	96.99	1	296	4	293	3.3e-68	224	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2904476494	481	47.26	275	478	11	191	4.0e-39	22.7	COG0477	MFS family permease	338
2904476494	481	78.59	21	309	6	306	4.0e-39	109	COG0477	MFS family permease	338
2904476495	240	86.64	1	240	27	227	1.2e-31	104.3	COG2045	Phosphosulfolactate phosphohydrolase or related enzyme	230
2904476496	307	94.35	5	296	12	295	5.4e-40	131.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2904476497	415	99.19	1	415	4	370	0.0e+00	511.4	COG5276	Uncharacterized conserved protein	370
2904476498	355	91.13	1	326	9	306	6.6e-41	134.4	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2904476499	360	98.32	5	359	2	352	1.6e-100	330.5	COG0371	Glycerol dehydrogenase or related enzyme, iron-containing ADH family	360
2904476502	163	98.1	1	163	1	155	3.7e-33	109	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2904476504	326	97.34	18	326	7	299	1.7e-76	251.5	COG2990	Uncharacterized protein VirK/YbjX	300
2904476505	521	97.42	1	478	5	457	2.3e-109	360.3	COG2211	Na+/melibiose symporter or related transporter	467
2904476509	904	96.48	1	904	27	958	0.0e+00	724.1	COG0474	Magnesium-transporting ATPase (P-type)	917
2904476510	557	99.07	13	548	4	533	0.0e+00	481.5	COG1283	Na+/phosphate symporter	533
2904476512	264	93.28	6	263	8	257	7.6e-64	209.7	COG1877	Trehalose-6-phosphatase	266
2904476513	468	95.93	1	465	14	484	0.0e+00	521.6	COG0380	Trehalose-6-phosphate synthase	486
2904476514	556	97.13	6	556	14	555	0.0e+00	725	COG1626	Neutral trehalase	558
2904476515	296	97.34	5	293	2	294	1.3e-45	150.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476516	242	96.53	1	242	6	255	4.1e-23	76.2	COG0730	Uncharacterized membrane protein YfcA	258
2904476517	132	89.78	2	130	11	133	2.9e-30	99.3	COG4319	Ketosteroid isomerase homolog	137
2904476518	329	90.29	5	304	2	252	7.8e-41	130.4	COG0388	Predicted amidohydrolase	274
2904476519	291	95.02	1	289	2	287	1.0e-53	177.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476520	154	69.75	10	143	41	153	1.2e-06	23.5	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904476521	131	93.81	1	127	1	91	9.4e-33	105.1	COG3141	dsDNA-binding SOS-regulon protein, induction by DNA damage requires cAMP	97
2904476522	210	89.45	11	203	16	210	2.8e-07	24.3	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2904476523	464	9.23	310	428	333	368	2.1e-10	9.5	COG0006	Xaa-Pro aminopeptidase	384
2904476523	464	60.51	24	285	7	242	2.1e-10	23.2	COG0006	Xaa-Pro aminopeptidase	384
2904476524	736	97.78	9	736	17	720	0.0e+00	842.5	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
2904476525	425	91.78	1	425	23	413	0.0e+00	470.4	COG1649	Uncharacterized lipoprotein YddW, UPF0748 family	418
2904476526	106	64.41	2	102	16	91	1.7e-21	71.1	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2904476527	429	99.53	1	424	3	424	0.0e+00	475.9	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
2904476528	143	98.29	2	118	2	116	2.9e-37	121.6	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2904476529	517	97.8	1	506	9	496	3.3e-126	416.2	COG3104	Dipeptide/tripeptide permease	498
2904476530	363	89.2	1	334	36	324	9.5e-42	137.7	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2904476531	709	97.61	13	709	20	795	4.9e-97	320.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904476532	302	97.52	11	291	7	281	5.9e-57	187.1	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2904476535	301	98.88	52	299	2	266	9.6e-66	216.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904476536	105	51.91	4	101	59	126	9.4e-20	65.3	COG5455	Periplasmic regulator RcnB of Ni and Co efflux	129
2904476537	539	99.26	8	538	4	536	0.0e+00	631.3	COG3290	Sensor histidine kinase regulating citrate/malate metabolism	537
2904476538	239	99.55	2	229	1	223	5.1e-88	288.6	COG4565	Response regulator of citrate/malate metabolism	224
2904476539	320	86.69	4	311	37	329	2.9e-92	303.2	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
2904476540	925	68.89	363	466	41	133	4.0e-13	42.9	COG3976	Uncharacterized protein, contains FMN-binding domain	135
2904476540	925	72.79	477	925	5	416	5.1e-80	263.1	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2904476540	925	93.66	1	364	5	344	9.3e-100	328.2	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2904476541	503	98.14	14	503	8	481	1.3e-116	384.2	COG0471	Di- and tricarboxylate transporter	461
2904476542	548	98.92	359	548	2	184	9.1e-76	246.4	COG1838	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain	184
2904476542	548	99.33	38	344	2	298	2.5e-109	359	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
2904476543	314	96.81	1	314	5	307	2.9e-41	135.9	COG0679	Predicted permease	311
2904476544	561	99.77	46	557	1	441	0.0e+00	497.3	COG0281	Malic enzyme	432
2904476548	225	76.12	1	212	4	207	4.3e-32	106	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904476549	200	92.82	5	200	4	197	7.3e-20	66.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904476550	307	98.64	26	306	2	292	1.6e-38	127.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904476551	412	47.26	221	409	14	194	3.3e-16	15.7	COG0477	MFS family permease	338
2904476551	412	71.28	14	277	2	274	3.3e-16	41.2	COG0477	MFS family permease	338
2904476552	577	96.82	2	502	2	519	2.9e-121	392.2	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2904476553	244	66.07	11	237	38	222	7.1e-33	108.5	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2904476554	414	98.8	3	410	6	416	6.6e-109	358.6	COG0814	Amino acid permease	415
2904476556	284	98.55	4	276	2	273	3.0e-90	296.6	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2904476557	284	99.28	1	273	1	274	2.0e-88	290.6	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2904476558	259	93.31	4	253	4	240	1.3e-92	304	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
2904476559	313	96.72	14	313	10	304	6.6e-101	331.6	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
2904476560	155	77.92	32	155	2	121	1.5e-39	129.1	COG1321	Mn-dependent transcriptional regulator, DtxR family	154
2904476563	270	99.26	1	266	1	270	8.1e-62	203.8	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
2904476564	390	47.26	17	200	10	190	6.7e-12	19.7	COG0477	MFS family permease	338
2904476564	390	48.04	210	389	6	189	6.7e-12	25.3	COG0477	MFS family permease	338
2904476565	332	16.13	249	317	226	275	2.0e-14	4.7	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2904476565	332	44.19	98	247	26	162	2.0e-14	40.7	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2904476566	131	99.32	1	126	2	146	9.4e-11	35.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2904476567	295	69.06	10	263	77	355	2.7e-32	105.4	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2904476569	624	98.56	1	624	8	625	0.0e+00	862.5	COG3158	K+ transporter	627
2904476572	856	99.63	11	846	2	803	0.0e+00	900.3	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2904476574	208	73.11	2	207	48	240	4.1e-14	46.9	COG3455	Type VI protein secretion system component VasF	262
2904476575	464	98.43	2	462	4	442	4.7e-65	214.1	COG3522	Predicted component of the type VI protein secretion system	446
2904476576	191	69.57	1	140	10	121	5.6e-09	29.3	COG3521	Predicted component of the type VI protein secretion system	159
2904476577	352	94.62	6	344	9	342	1.3e-23	72.1	COG3515	Predicted component of the type VI protein secretion system	346
2904476578	99	99	1	99	1	99	8.4e-27	87.7	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
2904476580	637	94.12	5	562	20	563	4.7e-129	425.5	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2904476581	315	90.75	1	313	20	323	1.1e-55	183.5	COG3520	Predicted component of the type VI protein secretion system	335
2904476582	600	99.03	2	599	3	617	0.0e+00	442.4	COG3519	Type VI protein secretion system component VasA	621
2904476583	138	64.97	1	119	9	110	2.8e-12	40.7	COG3518	Predicted component of the type VI protein secretion system	157
2904476584	163	92.41	1	161	4	149	4.1e-18	60.1	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2904476585	493	97.58	1	492	11	493	0.0e+00	653.6	COG3517	Predicted component of the type VI protein secretion system	495
2904476586	159	87.57	1	155	3	150	1.7e-51	168.6	COG3516	Predicted component of the type VI protein secretion system	169
2904476587	191	98.95	1	189	1	188	5.9e-66	216	COG1971	Putative Mn2+ efflux pump MntP	190
2904476588	323	97.34	3	302	1	293	7.1e-63	207.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476589	339	90.29	1	331	2	308	8.3e-45	147.4	COG0859	ADP-heptose:LPS heptosyltransferase	334
2904476590	360	98.24	35	356	3	336	5.5e-39	128.6	COG0859	ADP-heptose:LPS heptosyltransferase	334
2904476592	286	94.38	6	286	10	311	1.0e-65	207.4	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2904476593	304	98.01	6	304	1	295	1.3e-45	150.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476594	148	93.13	12	142	5	126	3.0e-15	50.6	COG5485	Predicted ester cyclase	131
2904476595	95	6.34	2	83	770	823	4.2e-04	12.9	COG3264	Small-conductance mechanosensitive channel	835
2904476596	386	99.47	2	382	3	379	0.0e+00	477.6	COG1454	Alcohol dehydrogenase, class IV	377
2904476598	223	80.38	2	217	9	176	1.7e-18	62.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904476599	334	78.12	1	294	13	287	9.3e-59	192.7	COG1566	Multidrug resistance efflux pump	352
2904476600	581	77.78	329	581	3	240	0.0e+00	288.8	COG1131	ABC-type multidrug transport system, ATPase component	293
2904476600	581	98.37	6	309	5	305	0.0e+00	257.3	COG1131	ABC-type multidrug transport system, ATPase component	293
2904476601	378	93.86	81	378	15	289	1.7e-37	123.7	COG0842	ABC-type multidrug transport system, permease component	286
2904476602	368	94.88	70	368	12	289	4.5e-38	125.3	COG0842	ABC-type multidrug transport system, permease component	286
2904476603	267	99.25	1	266	1	266	9.0e-62	203.3	COG0345	Pyrroline-5-carboxylate reductase	266
2904476604	392	96.69	1	385	10	389	1.9e-122	403.4	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2904476605	233	91.38	4	227	12	223	2.7e-53	175	COG1802	DNA-binding transcriptional regulator, GntR family	230
2904476606	375	93.44	12	367	5	346	1.5e-53	176.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2904476607	297	98.01	1	297	5	299	2.1e-52	172.8	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2904476608	295	91.02	1	295	26	319	9.0e-64	210.1	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2904476609	259	99.21	1	250	3	254	1.3e-82	271.2	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2904476610	239	98.73	1	236	3	236	2.9e-80	263.2	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2904476612	337	17.53	45	140	37	90	1.1e-07	6.5	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2904476612	337	22.4	169	304	217	285	1.1e-07	17.2	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2904476613	139	66.5	1	139	67	201	1.8e-38	126.6	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2904476614	420	98.66	1	360	3	371	8.4e-74	243	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2904476615	478	98.49	2	478	3	458	0.0e+00	590.7	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2904476616	717	99.51	34	709	1	608	0.0e+00	880.6	COG1966	Carbon starvation protein CstA	575
2904476617	67	100	1	67	1	65	7.0e-38	122.9	COG2879	Uncharacterized short protein YbdD, DUF466 family	65
2904476618	323	98.47	4	318	1	321	5.1e-91	299.6	COG0523	GTPase, G3E family	323
2904476619	239	98.79	1	239	1	245	5.4e-71	233.6	COG3279	DNA-binding response regulator, LytR/AlgR family	244
2904476620	562	99.28	3	562	2	554	0.0e+00	831.1	COG3275	Sensor histidine kinase, LytS/YehU family	557
2904476621	226	75.75	1	218	71	298	9.0e-24	79.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476622	283	96.95	9	280	7	292	1.2e-41	137.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904476623	200	94.42	1	200	1	203	8.2e-25	82.3	COG0625	Glutathione S-transferase	211
2904476624	368	95.06	1	336	17	324	1.3e-53	176.7	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2904476625	63	20	1	63	23	77	4.6e-05	17.7	COG0575	CDP-diglyceride synthetase	265
2904476626	595	93.68	1	590	20	612	0.0e+00	504	COG0296	1,4-alpha-glucan branching enzyme	628
2904476627	836	20.02	1	180	2	179	0.0e+00	254.5	COG3280	Maltooligosyltrehalose synthase	889
2904476627	836	67.6	170	833	234	834	0.0e+00	748.7	COG3280	Maltooligosyltrehalose synthase	889
2904476628	358	85.67	25	358	29	321	8.2e-53	173.9	COG0668	Small-conductance mechanosensitive channel	316
2904476629	490	95.68	26	490	9	451	7.6e-117	384.8	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
2904476630	461	94.84	10	457	22	444	0.0e+00	491	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2904476632	295	90.72	5	295	25	327	3.1e-57	188.5	COG2367	Beta-lactamase class A	329
2904476633	554	94.82	77	516	23	425	2.3e-109	360.9	COG0840	Methyl-accepting chemotaxis protein	408
2904476634	529	99.46	1	521	1	549	0.0e+00	580.1	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2904476635	271	87.58	2	264	27	287	2.0e-74	244.3	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904476636	339	98.74	25	339	3	316	1.3e-89	295	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904476637	514	94.98	2	511	14	562	3.6e-82	271.2	COG0747	ABC-type transport system, periplasmic component	556
2904476638	300	96.33	2	300	9	297	1.8e-63	208.8	COG2040	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)	300
2904476639	740	98.33	8	740	13	720	0.0e+00	865.3	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
2904476640	345	99.37	7	345	3	318	7.4e-93	305.5	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
2904476641	303	97.8	1	303	4	270	4.6e-43	141.7	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2904476642	255	97.11	7	246	7	241	5.5e-79	259.2	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
2904476644	396	94.41	17	362	17	354	8.8e-68	223.1	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2904476645	730	10.4	445	563	553	650	3.1e-73	3.3	COG1025	Secreted/periplasmic Zn-dependent peptidases, insulinase-like	937
2904476645	730	12.95	548	688	744	865	3.1e-73	51.4	COG1025	Secreted/periplasmic Zn-dependent peptidases, insulinase-like	937
2904476645	730	32.48	3	318	25	330	3.1e-73	183.2	COG1025	Secreted/periplasmic Zn-dependent peptidases, insulinase-like	937
2904476646	375	91.8	190	374	14	181	6.3e-53	173.1	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904476647	387	97.51	6	385	2	353	0.0e+00	457	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2904476648	88	30.62	2	82	157	235	7.1e-32	104.8	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
2904476651	441	97.14	18	430	8	415	3.0e-101	333.2	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
2904476652	170	91.48	1	165	12	172	5.2e-69	225.7	COG3721	Putative heme iron utilization protein	176
2904476653	207	47.1	3	175	4	133	9.4e-11	33.4	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2904476655	449	95.74	35	441	1	382	1.3e-63	209.4	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
2904476656	157	56.52	80	150	5	43	3.1e-07	23.5	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2904476657	106	98.11	1	105	2	105	1.4e-35	116.3	COG2076	Multidrug transporter EmrE and related cation transporters	106
2904476658	284	83.39	1	280	1	251	3.1e-41	136.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476659	237	99.13	1	237	1	227	6.7e-69	226.2	COG1811	Uncharacterized membrane protein YqgA, affects biofilm formation	228
2904476660	170	89.01	1	170	20	189	4.7e-69	226.2	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
2904476661	499	89.23	11	493	3	433	1.8e-81	267.5	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
2904476662	488	84.26	93	488	56	387	1.6e-61	203.2	COG0642	Signal transduction histidine kinase	336
2904476663	240	99.14	5	235	1	230	2.8e-83	273.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904476664	208	88.24	7	208	20	214	3.5e-61	200.9	COG4117	Thiosulfate reductase cytochrome b subunit	221
2904476665	267	88.24	34	267	3	257	8.9e-57	186.8	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2904476669	266	98.71	12	265	4	309	1.8e-89	294.3	COG0024	Methionine aminopeptidase	255
2904476670	160	83.21	7	136	2	115	5.3e-29	94.3	COG1695	DNA-binding transcriptional regulator, PadR family	138
2904476671	270	95.11	7	270	8	260	2.3e-67	221.4	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
2904476672	203	79.9	1	202	8	174	1.8e-24	81.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904476673	806	88.18	20	806	95	795	2.4e-63	209.2	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904476675	205	45.45	2	205	219	408	1.1e-28	94.6	COG2995	Uncharacterized paraquat-inducible protein A	418
2904476676	207	46.89	2	207	216	411	6.9e-66	217.2	COG2995	Uncharacterized paraquat-inducible protein A	418
2904476677	531	95.48	1	531	19	546	0.0e+00	454	COG3008	Paraquat-inducible protein B	553
2904476678	193	96.32	3	191	7	189	2.7e-33	109.4	COG3009	Uncharacterized lipoprotein YmbA	190
2904476679	163	86.86	11	140	4	122	4.6e-26	85.2	COG1695	DNA-binding transcriptional regulator, PadR family	138
2904476680	379	95.9	2	366	15	388	1.4e-75	249	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904476681	1038	99.9	1	1027	1	1013	0.0e+00	1182	COG0841	Multidrug efflux pump subunit AcrB	1009
2904476682	457	97.61	11	457	1	449	1.8e-122	403.8	COG1538	Outer membrane protein TolC	457
2904476683	128	86.52	1	128	11	132	1.3e-42	139.2	COG0229	Peptide methionine sulfoxide reductase MsrB	140
2904476684	805	99.74	1	805	3	774	0.0e+00	896.5	COG4775	Outer membrane protein assembly factor BamA	766
2904476685	312	98.42	4	312	2	312	7.0e-76	249.6	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2904476686	526	96.51	83	526	15	429	3.0e-41	136.1	COG4580	Maltoporin (phage lambda and maltose receptor)	429
2904476687	457	93.57	95	457	2	394	2.1e-82	271.6	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
2904476687	457	96.63	4	91	3	88	8.9e-28	90.1	COG1264	Phosphotransferase system IIB components	88
2904476688	469	90.34	2	464	22	470	4.2e-127	416.7	COG1621	Sucrose-6-phosphate hydrolase SacC, GH32 family	486
2904476689	341	97.9	7	336	2	328	7.4e-75	246.5	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904476690	272	47.28	6	270	3	263	2.3e-70	231.9	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2904476691	271	91.76	11	268	18	251	1.2e-71	235.3	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
2904476692	412	49.09	208	411	5	192	1.5e-20	14	COG0477	MFS family permease	338
2904476692	412	62.14	6	248	8	245	1.5e-20	59.6	COG0477	MFS family permease	338
2904476693	502	93.77	1	474	4	545	3.8e-49	160.7	COG0747	ABC-type transport system, periplasmic component	556
2904476694	595	76.17	336	587	55	281	5.7e-39	128.3	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904476694	595	90.88	25	318	10	298	1.9e-43	143.6	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904476695	326	73.68	6	183	16	113	7.3e-16	52	COG1846	DNA-binding transcriptional regulator, MarR family	126
2904476696	836	96.89	15	600	11	570	2.4e-72	238.2	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2904476699	84	80	1	84	13	92	5.1e-16	53.2	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
2904476701	1122	65.24	233	1103	414	1190	8.7e-111	365.3	COG3523	Type VI protein secretion system component VasK	1188
2904476702	177	93.79	6	177	8	158	6.4e-30	98.2	COG3521	Predicted component of the type VI protein secretion system	159
2904476703	591	99.68	1	591	1	619	7.6e-106	349.3	COG3519	Type VI protein secretion system component VasA	621
2904476704	361	94.03	35	361	19	333	1.3e-78	258.8	COG3520	Predicted component of the type VI protein secretion system	335
2904476705	261	99.22	4	255	1	253	3.5e-96	315.8	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
2904476706	288	85.54	14	288	1	278	1.0e-98	324.7	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2904476707	301	91.28	10	301	24	295	4.7e-102	335.2	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904476708	353	97.8	17	353	5	315	7.0e-108	355	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904476709	547	95.5	6	536	17	568	3.2e-86	284.6	COG0747	ABC-type transport system, periplasmic component	556
2904476710	384	93.3	1	384	23	370	3.2e-79	260.7	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2904476711	220	87.4	1	218	21	242	1.8e-37	123.8	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2904476712	301	98.34	4	299	1	296	1.0e-40	134.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476713	473	49.09	269	469	6	193	8.3e-38	37	COG0477	MFS family permease	338
2904476713	473	81.2	16	289	5	315	8.3e-38	93.5	COG0477	MFS family permease	338
2904476714	229	73.48	1	229	5	234	5.0e-73	240.7	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2904476715	123	18.8	1	45	1	25	9.5e-08	6.1	COG3607	Predicted lactoylglutathione lyase	133
2904476715	123	36.09	50	121	75	122	9.5e-08	18.9	COG3607	Predicted lactoylglutathione lyase	133
2904476716	79	94.05	1	79	1	79	9.8e-42	134.6	COG3813	Uncharacterized protein	84
2904476718	219	64.78	3	203	101	295	1.2e-22	75.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476719	327	19.9	233	325	292	367	5.2e-60	20.3	COG3268	Uncharacterized conserved protein, related to short-chain dehydrogenases	382
2904476719	327	63.87	1	242	8	251	5.2e-60	176.7	COG3268	Uncharacterized conserved protein, related to short-chain dehydrogenases	382
2904476720	134	98.63	1	126	2	145	4.0e-06	22	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2904476721	247	98.13	1	246	5	267	1.0e-61	203.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904476722	300	75	170	297	22	120	3.0e-21	69.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904476723	105	20.12	1	93	117	184	4.9e-11	36.3	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
2904476724	799	99.87	10	795	2	773	0.0e+00	1161.7	COG4993	Glucose dehydrogenase	773
2904476725	717	91.32	7	714	67	792	4.0e-78	258.1	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904476726	252	90.85	7	250	23	290	1.6e-19	64.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904476727	325	20.8	4	273	251	493	1.3e-06	20.2	COG1196	Chromosome segregation ATPase	1163
2904476729	479	98.96	6	479	2	475	0.0e+00	561.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2904476730	274	74.24	158	274	27	124	5.8e-28	91.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904476731	330	86.85	1	328	18	301	2.4e-64	211.5	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2904476732	504	99.4	1	499	3	500	0.0e+00	628.3	COG1129	ABC-type sugar transport system, ATPase component	500
2904476733	337	96.87	2	318	8	316	2.2e-90	296.9	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2904476734	340	94.98	25	339	9	311	4.9e-84	276.1	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2904476735	257	73.68	2	257	13	278	2.1e-50	166.1	COG3177	Fic family protein	348
2904476736	307	98.06	1	307	1	303	3.4e-70	231	COG1893	Ketopantoate reductase	307
2904476737	160	98.1	1	160	1	155	1.1e-40	133.5	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2904476740	177	97.79	1	177	4	180	6.6e-52	170.1	COG3038	Cytochrome b561	181
2904476741	115	86.72	1	114	17	127	5.9e-33	108.5	COG2916	DNA-binding protein H-NS	128
2904476743	294	96.01	1	290	1	289	9.7e-62	203.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476744	461	95.62	2	461	19	476	0.0e+00	479.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2904476745	344	70.6	1	343	99	439	2.4e-75	248.2	COG3037	Ascorbate-specific PTS system EIIC-type component UlaA	481
2904476749	100	72.16	30	100	4	73	1.6e-21	70.8	COG2314	Uncharacterized membrane protein YozV, TM2 domain	95
2904476750	398	99.75	1	397	1	397	0.0e+00	666.4	COG3007	Trans-2-enoyl-CoA reductase	398
2904476752	366	22.58	188	294	34	61	5.7e-14	26.3	COG1145	Ferredoxin	99
2904476752	366	42.74	289	365	39	91	5.7e-14	25	COG1145	Ferredoxin	99
2904476753	485	38.38	301	473	51	197	6.7e-46	21.9	COG0477	MFS family permease	338
2904476753	485	85.12	23	325	5	330	6.7e-46	133.9	COG0477	MFS family permease	338
2904476754	224	91.81	3	222	12	224	1.8e-55	182.1	COG1802	DNA-binding transcriptional regulator, GntR family	230
2904476755	374	90.16	170	369	17	181	2.2e-44	145.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904476756	419	95.52	2	417	19	444	2.6e-125	412.7	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2904476757	349	93.43	8	339	12	324	6.0e-64	210	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2904476758	247	98.88	3	246	3	267	8.2e-58	190.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904476759	279	96.25	11	275	7	263	9.4e-90	294.5	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2904476760	421	17.01	22	109	9	57	3.3e-87	5.8	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2904476760	421	93.75	135	420	13	282	3.3e-87	281.3	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2904476761	342	96.03	1	340	15	377	3.1e-67	221.4	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2904476762	422	95.52	1	422	18	443	0.0e+00	515.8	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2904476763	518	99.12	20	496	3	454	0.0e+00	463.9	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2904476764	362	98.87	1	359	3	351	2.6e-130	429.1	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2904476765	208	20.45	2	74	2	55	3.5e-37	76	COG1192	Cellulose biosynthesis protein BcsQ	259
2904476765	208	55.3	56	208	113	258	3.5e-37	46.5	COG1192	Cellulose biosynthesis protein BcsQ	259
2904476768	328	58.33	1	250	18	220	1.4e-28	94.1	COG5527	Protein involved in initiation of plasmid replication	342
2904476773	249	83.45	3	240	39	275	1.5e-37	123.8	COG2801	Transposase InsO and inactivated derivatives	232
2904476775	163	98.1	1	163	1	155	1.8e-36	119.7	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2904476776	63	13.84	2	57	305	353	2.0e-06	21.4	COG3500	Phage protein D	350
2904476778	73	30.13	2	67	1	47	3.5e-04	15	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
2904476779	570	95.67	15	565	10	562	5.8e-99	326.7	COG0747	ABC-type transport system, periplasmic component	556
2904476780	319	99.37	1	319	1	316	6.2e-110	361.8	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904476781	315	96.64	17	313	10	297	6.8e-94	308.3	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904476782	334	98.46	5	320	2	321	6.5e-126	413.9	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2904476783	321	97.81	3	315	3	315	2.8e-120	395.6	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2904476784	291	91.36	2	282	18	292	7.7e-46	151.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476785	290	87.18	13	279	33	270	4.9e-75	246.8	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2904476786	471	86.52	3	88	4	80	7.9e-23	74.1	COG1264	Phosphotransferase system IIB components	88
2904476786	471	93.33	96	467	8	399	6.0e-58	190.9	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
2904476787	399	96.51	2	383	12	371	1.3e-83	275.1	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2904476788	236	90.38	1	214	9	224	2.3e-42	139.3	COG2188	DNA-binding transcriptional regulator, GntR family	236
2904476789	98	54.62	16	98	9	79	2.2e-12	42.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2904476791	84	13.03	9	68	340	391	1.5e-04	15	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
2904476796	825	99.74	10	823	3	773	0.0e+00	919	COG4993	Glucose dehydrogenase	773
2904476797	295	95.02	3	293	2	287	5.0e-38	125.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476798	519	97.4	1	518	7	569	9.5e-112	369	COG0747	ABC-type transport system, periplasmic component	556
2904476799	294	97.99	1	294	2	294	2.4e-82	270.4	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2904476800	316	99.04	2	314	3	312	4.6e-99	326	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
2904476801	320	99.04	1	312	2	311	1.2e-92	304.9	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
2904476802	324	99.37	1	322	1	316	6.9e-107	351.8	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904476803	305	92.28	7	305	22	296	6.0e-99	325	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904476804	601	99.46	2	562	3	551	0.0e+00	727.5	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2904476805	319	65.03	77	305	113	324	8.7e-10	29.6	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2904476806	86	92.59	1	80	6	80	1.2e-10	35.7	COG0236	Acyl carrier protein	80
2904476808	450	92.83	6	448	16	442	1.5e-28	93.6	COG0534	Na+-driven multidrug efflux pump	455
2904476809	351	22.71	224	323	219	285	3.6e-20	17.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904476809	351	36.95	93	253	24	132	3.6e-20	47.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904476810	181	39.08	6	148	192	318	3.0e-19	63.4	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2904476811	416	92.82	10	411	10	371	2.1e-23	77.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904476812	263	96.9	26	258	2	220	5.3e-85	278.4	COG1136	ABC-type lipoprotein export system, ATPase component	226
2904476813	809	28.04	619	809	368	510	1.9e-41	74.5	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2904476813	809	74.51	52	404	120	499	1.9e-41	61.8	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2904476814	470	98.29	1	470	1	459	0.0e+00	512.8	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904476815	437	51.26	34	437	343	707	2.0e-46	153.1	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
2904476816	229	56.95	35	207	46	172	1.1e-29	97.5	COG2091	Phosphopantetheinyl transferase	223
2904476818	351	92.42	14	350	18	334	2.1e-45	149.4	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2904476819	438	83.14	3	423	48	397	6.9e-43	141.2	COG2124	Cytochrome P450	411
2904476822	376	18.8	269	365	314	388	8.8e-29	11	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2904476822	376	49.87	41	261	66	264	8.8e-29	84.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2904476824	243	22.37	131	232	223	288	7.0e-13	25.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904476824	243	45.08	3	168	25	157	7.0e-13	21.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904476828	504	94.57	5	502	18	539	3.4e-51	160.3	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2904476829	517	61.27	6	427	248	644	1.3e-51	170.2	COG1020	Non-ribosomal peptide synthetase component F	642
2904476830	84	70.37	2	80	23	79	1.4e-07	25.8	COG0236	Acyl carrier protein	80
2904476831	526	97.18	1	522	8	559	1.1e-102	338.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2904476834	435	97.47	8	404	11	395	1.4e-91	301.3	COG0019	Diaminopimelate decarboxylase	394
2904476836	111	96.23	2	107	4	105	2.9e-30	99.2	COG2076	Multidrug transporter EmrE and related cation transporters	106
2904476837	403	97.22	9	398	6	389	2.4e-96	316.9	COG2814	Predicted arabinose efflux permease, MFS family	394
2904476838	270	97.78	1	270	7	270	1.1e-102	337.1	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
2904476840	111	93.75	1	111	7	111	4.1e-22	72.8	COG4538	Uncharacterized protein	112
2904476841	59	38.33	1	53	5	27	1.2e-06	22.5	COG5475	Uncharacterized conserved protein YodC, DUF2158 family	60
2904476842	143	97.9	4	142	2	141	2.3e-41	135.6	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2904476846	90	80.6	8	69	5	58	2.5e-12	40.8	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2904476847	199	43.37	4	197	54	174	2.6e-08	28.8	COG0500	SAM-dependent methyltransferase	257
2904476848	413	88.72	146	405	15	242	4.9e-43	140.9	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2904476853	180	83.42	1	170	5	160	6.3e-34	112	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2904476854	304	98.34	2	301	2	297	3.1e-72	238.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476855	462	51.96	251	459	8	206	5.1e-37	23.6	COG0477	MFS family permease	338
2904476855	462	69.97	3	255	8	275	5.1e-37	104.4	COG0477	MFS family permease	338
2904476856	129	95.38	1	129	3	126	3.8e-35	115.6	COG4460	Uncharacterized protein	130
2904476857	423	28.05	3	108	50	95	6.1e-43	17.5	COG2010	Cytochrome c, mono- and diheme variants	150
2904476857	423	64.63	290	423	55	160	6.1e-43	50	COG2010	Cytochrome c, mono- and diheme variants	150
2904476857	423	98.78	113	287	1	162	6.1e-43	76	COG2010	Cytochrome c, mono- and diheme variants	150
2904476858	589	97.89	2	587	4	559	8.6e-56	184.1	COG2303	Choline dehydrogenase or related flavoprotein	542
2904476860	340	98.5	15	340	1	329	5.9e-88	289.6	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904476861	106	98.04	3	102	2	101	1.5e-35	115.7	COG1440	Phosphotransferase system cellobiose-specific component IIB	102
2904476862	452	99.08	1	448	1	430	0.0e+00	487	COG1455	Phosphotransferase system cellobiose-specific component IIC	432
2904476863	115	97.14	13	115	2	103	3.4e-40	130.6	COG1447	Phosphotransferase system cellobiose-specific component IIA	105
2904476864	278	65.15	127	277	40	125	6.8e-22	71.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904476865	447	99.55	2	442	2	441	0.0e+00	521.6	COG1486	Alpha-galactosidase/6-phospho-beta-glucosidase, family 4 of glycosyl hydrolase	442
2904476866	252	100	1	252	1	257	2.9e-102	336	COG3394	Predicted glycoside hydrolase or deacetylase ChbG, UPF0249 family	257
2904476867	296	96.44	5	294	3	300	8.8e-50	163.8	COG1893	Ketopantoate reductase	307
2904476868	275	94.68	1	275	9	293	3.4e-20	66.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2904476869	302	98.01	6	300	5	299	6.5e-59	194.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904476870	626	99.25	4	542	4	534	0.0e+00	568.9	COG1574	Predicted amidohydrolase YtcJ	535
2904476871	188	93.85	1	188	2	184	2.7e-44	145.2	COG3224	Antibiotic biosynthesis monooxygenase (ABM) superfamily enzyme	195
2904476872	138	87.5	10	135	9	113	2.0e-39	128.1	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2904476873	285	99.64	1	269	2	276	3.1e-72	237.6	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2904476875	178	57.84	1	177	2	108	8.5e-18	59.4	COG0563	Adenylate kinase or related kinase	178
2904476876	177	94.09	1	176	2	176	2.4e-65	214	COG1443	Isopentenyldiphosphate isomerase	185
2904476879	160	96.84	1	160	1	153	4.9e-41	134.6	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2904476880	127	81.2	1	125	21	128	8.7e-23	75.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
2904476881	459	96.77	1	458	6	455	0.0e+00	436.3	COG2211	Na+/melibiose symporter or related transporter	467
2904476882	679	72.19	28	676	116	681	0.0e+00	548.2	COG1501	Alpha-glucosidase, glycosyl hydrolase family GH31	772
2904476883	168	88.65	41	168	5	129	9.4e-51	165.5	COG0229	Peptide methionine sulfoxide reductase MsrB	140
2904476884	242	92.53	54	236	4	164	6.2e-61	199.5	COG0225	Peptide methionine sulfoxide reductase MsrA	174
2904476887	260	67.57	1	139	11	110	1.6e-15	47.2	COG3710	DNA-binding winged helix-turn-helix (wHTH) domain	148
2904476888	376	52.27	92	370	138	321	2.6e-57	185.5	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2904476889	186	95.34	2	184	5	188	2.8e-26	86.4	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
2904476890	343	99.4	1	339	3	331	2.5e-91	300.5	COG0620	Methionine synthase II (cobalamin-independent)	330
2904476892	111	94.34	1	101	2	101	7.7e-19	61.9	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
2904476893	130	83.8	1	128	5	123	4.7e-10	33.7	COG4747	Uncharacterized conserved protein, contains tandem ACT domains	142
2904476894	236	72.88	7	135	9	94	1.1e-13	45.2	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2904476895	401	48.56	203	399	10	195	7.5e-12	15.3	COG0477	MFS family permease	338
2904476895	401	50.39	2	204	3	195	7.5e-12	30.3	COG0477	MFS family permease	338
2904476896	412	95.27	11	411	8	410	2.3e-124	409.2	COG0738	Fucose permease	422
2904476897	114	97.14	2	111	3	104	2.1e-14	47.9	COG3254	L-rhamnose mutarotase	105
2904476898	258	98.88	3	254	3	267	4.3e-58	191.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904476899	284	97.14	1	276	8	279	1.0e-53	177.1	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2904476900	425	92.76	1	425	23	368	1.0e-84	278.4	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2904476901	280	97.8	10	280	5	271	2.5e-90	297	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2904476902	246	99.63	1	245	1	267	3.2e-65	214.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904476903	253	94.61	1	253	3	230	3.8e-56	176.9	COG2186	DNA-binding transcriptional regulator, FadR family	241
2904476904	49	11.25	1	46	53	79	2.6e-03	11.8	COG3398	Predicted transcriptional regulator, containsd two HTH domains	240
2904476905	334	98.26	1	334	6	344	8.4e-114	374.8	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
2904476906	477	97.59	3	453	2	446	0.0e+00	562.3	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
2904476907	412	96.96	13	400	6	388	2.2e-101	333.4	COG2814	Predicted arabinose efflux permease, MFS family	394
2904476908	321	76.52	172	321	20	120	1.1e-24	80.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904476909	299	96.61	7	296	10	294	5.0e-39	128.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904476910	251	75	184	249	17	76	3.0e-19	62.3	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2904476911	312	98.74	3	312	3	316	4.4e-105	345.8	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904476912	286	92.28	1	286	19	293	3.9e-90	296.2	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904476913	325	97.85	3	315	5	322	1.9e-118	389.4	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2904476914	349	95.31	11	320	3	307	7.4e-108	354.9	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2904476915	504	96.02	4	504	17	571	6.9e-114	376	COG0747	ABC-type transport system, periplasmic component	556
2904476916	498	50.39	255	494	22	214	3.2e-38	29.9	COG0477	MFS family permease	338
2904476916	498	72.58	4	304	4	281	3.2e-38	97.8	COG0477	MFS family permease	338
2904476917	192	88.52	1	192	12	196	1.1e-19	66.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904476919	335	97.97	1	335	6	343	4.8e-113	372.3	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
2904476920	474	98.25	3	453	2	449	0.0e+00	566	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
2904476922	461	94.33	2	345	19	351	1.2e-41	137.7	COG3515	Predicted component of the type VI protein secretion system	346
2904476923	142	92.36	1	142	7	151	9.3e-27	87.8	COG3518	Predicted component of the type VI protein secretion system	157
2904476924	180	90.68	1	179	5	150	9.6e-30	97.6	COG3521	Predicted component of the type VI protein secretion system	159
2904476925	365	95.82	1	347	1	321	2.8e-72	238.1	COG3520	Predicted component of the type VI protein secretion system	335
2904476926	587	99.68	1	587	1	619	0.0e+00	572.1	COG3519	Type VI protein secretion system component VasA	621
2904476932	835	94.98	8	601	13	561	8.9e-86	282.3	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2904476933	534	98.3	14	423	5	351	3.3e-69	227.9	COG3515	Predicted component of the type VI protein secretion system	346
2904476936	88	85	1	88	15	99	1.5e-22	74.1	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
2904476943	848	94.64	15	612	23	569	2.7e-87	287	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2904476947	885	98.26	11	879	2	792	0.0e+00	952.5	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2904476948	163	98.1	1	163	1	155	4.8e-49	160.6	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2904476949	564	60.3	367	549	79	198	3.1e-39	129.3	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2904476950	217	78.79	7	216	46	253	1.7e-43	143.1	COG3455	Type VI protein secretion system component VasF	262
2904476951	445	99.33	1	444	3	445	4.7e-121	398.9	COG3522	Predicted component of the type VI protein secretion system	446
2904476952	513	93.13	3	513	34	494	0.0e+00	720.7	COG3517	Predicted component of the type VI protein secretion system	495
2904476953	164	95.86	1	164	5	166	3.9e-60	196.7	COG3516	Predicted component of the type VI protein secretion system	169
2904476955	477	91.76	17	474	36	425	1.4e-104	345	COG0840	Methyl-accepting chemotaxis protein	408
2904476956	447	81.65	36	447	78	424	5.2e-94	310.2	COG0840	Methyl-accepting chemotaxis protein	408
2904476958	374	82.69	40	342	45	321	3.7e-24	80	COG0582	Integrase	309
2904476959	713	19.26	461	580	59	105	5.5e-14	20.3	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2904476959	713	25	566	656	103	163	5.5e-14	23.8	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2904476959	713	75.38	165	461	62	312	1.7e-25	83.7	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2904476961	478	17.7	331	399	150	186	3.7e-08	8	COG0400	Predicted esterase	207
2904476961	478	24.88	92	170	85	136	3.7e-08	17.3	COG0400	Predicted esterase	207
2904476963	288	79.55	2	123	21	125	5.2e-25	81.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904476964	259	99.63	1	257	1	267	5.9e-71	233.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904476967	223	56.11	1	223	1	202	2.8e-72	238	COG3203	Outer membrane protein (porin)	354
2904476968	374	86.27	43	373	36	324	1.0e-18	62.3	COG0582	Integrase	309
2904476972	275	93.68	6	274	17	268	6.0e-88	289.2	COG5532	Uncharacterized conserved protein YfdQ, DUF2303 family	269
2904476974	63	44.23	3	62	24	69	4.5e-04	13.7	COG4888	Transcription elongation factor Elf1, contains Zn-ribbon domain	104
2904476977	224	96.06	10	224	5	199	1.0e-40	133.6	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2904476978	67	47.92	2	61	10	55	1.9e-04	15.7	COG4197	DNA-binding transcriptional regulator YdaS, prophage-encoded, Cro superfamily	96
2904476988	172	84.71	1	169	1	144	1.7e-29	96.8	COG4283	Uncharacterized protein	170
2904476990	103	98.04	1	101	1	100	6.3e-18	59.2	COG1440	Phosphotransferase system cellobiose-specific component IIB	102
2904476992	278	94.57	17	278	15	258	2.0e-45	149.6	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
2904476993	225	98.28	1	219	2	229	9.0e-68	222.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904476994	445	71.83	50	445	106	388	2.8e-60	199.3	COG0642	Signal transduction histidine kinase	336
2904476998	155	65.08	9	148	45	167	5.1e-13	43.6	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2904476999	302	97.67	2	296	1	294	1.9e-58	192.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904477000	201	99.07	1	201	1	213	3.6e-38	125.9	COG0625	Glutathione S-transferase	211
2904477002	542	99.28	1	535	3	550	0.0e+00	626.1	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2904477003	289	95.82	4	289	11	285	1.6e-41	136.5	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2904477004	332	98.48	2	325	4	328	9.6e-52	170.5	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2904477005	333	97.52	3	330	4	318	9.6e-92	301.7	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
2904477006	460	93.06	6	450	16	404	7.4e-44	144.5	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2904477007	304	99.37	1	304	1	316	2.6e-113	372.9	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904477008	281	89.6	2	281	25	291	3.5e-90	296.3	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904477009	497	92.91	3	492	21	557	9.8e-109	358.9	COG0747	ABC-type transport system, periplasmic component	556
2904477010	221	92.24	1	219	8	221	5.3e-50	164.3	COG1802	DNA-binding transcriptional regulator, GntR family	230
2904477011	503	97.1	19	503	12	480	6.9e-110	362	COG0471	Di- and tricarboxylate transporter	461
2904477013	925	67.41	364	466	42	132	9.9e-16	51.2	COG3976	Uncharacterized protein, contains FMN-binding domain	135
2904477013	925	72.61	477	925	6	416	3.5e-83	273.6	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2904477013	925	91.74	2	363	4	336	9.8e-95	311.5	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2904477014	295	97.67	2	295	2	295	7.9e-68	223.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904477015	214	97.16	1	205	2	206	4.2e-42	138.1	COG2085	Predicted dinucleotide-binding enzyme	211
2904477016	225	75	6	225	50	247	6.3e-41	134.6	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
2904477017	221	94.74	1	216	12	227	1.7e-57	188.9	COG0765	ABC-type amino acid transport system, permease component	222
2904477018	217	91.67	2	217	17	225	3.5e-59	194.4	COG0765	ABC-type amino acid transport system, permease component	222
2904477019	215	78.03	2	214	43	248	3.7e-22	72.9	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
2904477020	209	75.38	4	208	50	248	1.8e-45	149.3	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
2904477021	278	94.7	1	272	6	273	2.5e-48	159	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904477022	283	98.94	4	281	3	281	3.1e-52	171.7	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2904477023	333	75.31	180	299	34	155	1.8e-11	37.6	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904477023	333	82.71	8	144	16	125	9.1e-15	48.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
2904477024	516	66.67	20	513	203	644	8.2e-99	325.7	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2904477025	227	94.91	1	212	8	212	1.6e-32	107.4	COG0778	Nitroreductase	207
2904477026	2849	25	1539	1837	288	551	0.0e+00	85.2	COG3459	Cellobiose phosphorylase	1056
2904477026	2849	99.43	1757	2844	2	1051	0.0e+00	960.2	COG3459	Cellobiose phosphorylase	1056
2904477027	232	99.14	4	232	1	230	2.4e-70	230.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904477028	394	81.47	17	394	69	389	6.2e-50	165.2	COG0642	Signal transduction histidine kinase	336
2904477029	735	97.74	13	735	19	795	3.0e-68	225.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904477032	769	83.33	487	625	22	141	2.6e-08	25.8	COG3793	Tellurite resistance protein	144
2904477034	732	67.63	1	624	2	586	8.8e-109	359.1	COG1201	Lhr-like helicase	814
2904477036	1209	21.05	639	726	54	105	3.0e+00	4.9	COG3879	Uncharacterized conserved protein YlxW, UPF0749 family	247
2904477036	1209	25.91	724	816	35	98	3.0e+00	2.1	COG3879	Uncharacterized conserved protein YlxW, UPF0749 family	247
2904477039	111	55.17	1	53	7	38	7.9e-04	13.3	COG5567	Predicted small periplasmic lipoprotein YifL (function unknown0	58
2904477046	150	62.95	2	150	83	223	9.4e-51	166.7	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
2904477047	308	75.52	28	304	60	312	4.8e-32	105.9	COG0582	Integrase	309
2904477048	242	21.88	78	105	7	20	1.6e-03	3.9	COG2093	RNA polymerase subunit RPABC4/transcription elongation factor Spt4	64
2904477048	242	34.38	127	157	6	27	1.6e-03	7.7	COG2093	RNA polymerase subunit RPABC4/transcription elongation factor Spt4	64
2904477050	61	80	1	61	9	64	6.4e-23	75	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2904477053	629	20	1	114	9	99	2.2e-25	50.1	COG1479	Uncharacterized conserved protein, contains ParB-like and HNH nuclease domains	409
2904477053	629	43.3	192	446	193	389	2.2e-25	31.2	COG1479	Uncharacterized conserved protein, contains ParB-like and HNH nuclease domains	409
2904477055	1092	25.46	564	906	254	377	9.9e-12	7.5	COG1061	Superfamily II DNA or RNA helicase	442
2904477055	1092	31.01	227	432	37	187	9.9e-12	26.3	COG1061	Superfamily II DNA or RNA helicase	442
2904477058	672	14.19	401	480	212	254	6.1e-11	19.3	COG0863	DNA modification methylase	302
2904477058	672	39.27	94	316	16	134	6.1e-11	15.2	COG0863	DNA modification methylase	302
2904477059	1023	99.7	1	1023	1	981	0.0e+00	852	COG3587	Restriction endonuclease	985
2904477060	397	97.01	83	384	8	332	1.7e-35	117.1	COG0582	Integrase	309
2904477061	363	100	1	363	1	372	0.0e+00	510.4	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
2904477062	493	91.65	4	485	19	534	2.0e-115	376.7	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2904477063	652	37.87	159	399	49	162	8.4e-24	23.1	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2904477063	652	81.73	302	602	10	255	8.4e-24	56.2	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2904477064	344	91.69	38	335	9	284	9.6e-41	134.2	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2904477065	347	92.69	13	342	9	287	4.3e-32	105.7	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2904477066	634	87.41	2	632	90	728	0.0e+00	570.3	COG2217	Cation transport ATPase	713
2904477067	196	98.94	3	193	2	188	2.9e-74	243	COG0193	Peptidyl-tRNA hydrolase	190
2904477069	315	98.74	1	314	5	318	0.0e+00	443.5	COG0462	Phosphoribosylpyrophosphate synthetase	314
2904477070	287	98.28	1	276	5	289	3.6e-98	322.6	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
2904477071	207	99.03	1	207	1	204	8.7e-77	251.7	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
2904477072	420	99.28	1	420	1	411	0.0e+00	530.4	COG0373	Glutamyl-tRNA reductase	414
2904477073	360	99.72	1	359	1	362	0.0e+00	560.6	COG0216	Protein chain release factor A	363
2904477074	289	97.91	1	278	4	284	2.2e-85	280.5	COG2890	Methylase of polypeptide chain release factors	280
2904477075	96	73.64	1	95	35	129	9.1e-39	126.8	COG3094	Uncharacterized membrane protein SirB2	129
2904477076	269	99.63	1	269	2	270	2.6e-98	322.9	COG2912	Regulator of sirC expression, contains transglutaminase-like and TPR domains	269
2904477077	284	98.92	1	282	3	278	0.0e+00	457	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
2904477078	555	94.32	11	555	11	541	0.0e+00	491.1	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2904477079	235	91.98	19	206	16	187	3.0e-25	83.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2904477080	440	43.29	1	106	43	113	1.7e-42	16.1	COG2010	Cytochrome c, mono- and diheme variants	150
2904477080	440	57.32	296	426	66	159	1.7e-42	52.1	COG2010	Cytochrome c, mono- and diheme variants	150
2904477080	440	99.39	111	285	1	163	1.7e-42	72.2	COG2010	Cytochrome c, mono- and diheme variants	150
2904477081	534	97.36	1	534	6	558	1.7e-65	215.2	COG2303	Choline dehydrogenase or related flavoprotein	542
2904477083	158	92.2	26	158	8	137	8.4e-24	78.5	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2904477084	659	94.61	1	173	1	158	2.1e-52	171.6	COG1142	Fe-S-cluster-containing hydrogenase component 2	165
2904477084	659	97.82	200	649	1	448	0.0e+00	517.2	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2904477085	517	86.39	1	379	32	380	1.6e-31	104.2	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2904477086	257	97.25	10	256	5	252	1.3e-89	294.3	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
2904477087	276	83.69	2	272	1	272	1.9e-102	336.8	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2904477088	308	93.96	19	308	16	295	1.4e-100	330.4	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904477089	337	97.48	4	337	6	315	2.2e-107	353.4	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904477090	531	94.12	2	531	28	571	1.3e-81	269.5	COG0747	ABC-type transport system, periplasmic component	556
2904477091	370	99.69	12	370	1	317	4.8e-96	315.9	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
2904477093	524	39.94	385	524	57	201	0.0e+00	73.3	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2904477093	524	100	17	380	1	363	0.0e+00	564.9	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2904477094	463	100	1	463	1	470	0.0e+00	775.2	COG1282	NAD/NADP transhydrogenase beta subunit	463
2904477095	319	94.34	150	303	9	158	3.0e-34	82.5	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2904477095	319	97.48	1	149	3	157	3.0e-34	29.4	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2904477096	262	94.04	29	248	12	216	2.4e-50	165.3	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2904477097	341	16.41	12	64	174	215	7.0e-69	4.1	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2904477097	341	96.88	55	341	2	249	7.0e-69	226.4	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2904477099	271	97.45	1	270	5	271	8.9e-77	252.1	COG3769	Predicted mannosyl-3-phosphoglycerate phosphatase, HAD superfamily	274
2904477100	188	95.11	1	175	9	183	3.8e-48	158.3	COG2840	DNA-nicking endonuclease, Smr domain	184
2904477101	346	98.52	6	343	5	337	2.8e-111	365.8	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
2904477102	760	97.87	50	758	7	695	0.0e+00	884.8	COG1523	Pullulanase/glycogen debranching enzyme	697
2904477103	314	95.41	1	314	14	325	2.2e-84	277.5	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2904477104	293	88.37	1	273	25	290	3.5e-55	182.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904477105	647	99.84	1	647	1	644	0.0e+00	1119.8	COG4776	Exoribonuclease II	645
2904477106	768	95.68	9	759	35	809	0.0e+00	456.2	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2904477107	389	96.69	1	389	8	387	4.5e-125	412.2	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2904477108	419	52.74	216	417	3	204	4.9e-24	42.9	COG0477	MFS family permease	338
2904477108	419	59.53	8	249	11	238	4.9e-24	40.1	COG0477	MFS family permease	338
2904477110	240	68.31	1	227	7	228	1.0e-33	110.9	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2904477111	312	92.54	1	312	16	325	2.2e-60	199	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2904477112	365	94.75	8	354	17	341	9.3e-70	229.6	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2904477113	297	97.34	1	295	1	293	3.5e-57	188.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904477114	201	97.91	1	194	5	191	1.6e-50	166.1	COG5553	Predicted metal-dependent enzyme of the double-stranded beta helix superfamily	191
2904477115	539	78.95	273	380	5	94	3.8e-46	33.8	COG0607	Rhodanese-related sulfurtransferase	110
2904477115	539	85.09	8	117	12	108	3.8e-46	36.2	COG0607	Rhodanese-related sulfurtransferase	110
2904477115	539	90.35	137	244	8	110	3.8e-46	53.2	COG0607	Rhodanese-related sulfurtransferase	110
2904477115	539	92.11	382	487	9	113	3.8e-46	21.8	COG0607	Rhodanese-related sulfurtransferase	110
2904477116	88	26.91	1	84	167	233	1.0e-03	13.3	COG3541	Predicted nucleotidyltransferase	248
2904477119	108	99.08	1	108	1	108	7.2e-41	133.2	COG1742	Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily	109
2904477120	301	94.68	6	300	7	291	7.9e-46	151.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904477122	412	93.91	1	411	24	439	0.0e+00	549.5	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
2904477123	249	96.75	1	240	8	245	9.1e-106	347.3	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2904477124	351	97.81	1	322	1	313	4.0e-109	358.6	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2904477125	364	99.71	1	354	1	349	0.0e+00	438.6	COG3839	ABC-type sugar transport system, ATPase component	338
2904477126	317	94.62	10	314	3	301	3.6e-48	158.4	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2904477127	279	97.17	1	278	9	283	1.1e-72	239.2	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2904477128	300	96.31	1	297	6	292	1.8e-94	310.7	COG1175	ABC-type sugar transport system, permease component	295
2904477129	416	96.61	1	416	12	439	2.0e-73	242.6	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2904477130	391	97.1	79	383	1	301	1.1e-58	192.7	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2904477132	450	95.75	11	447	12	417	4.8e-117	385.2	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2904477133	222	81.34	1	205	7	176	6.9e-20	66.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904477134	467	97.77	1	467	8	489	0.0e+00	613.8	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
2904477135	799	98.85	7	786	4	775	0.0e+00	1244.1	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
2904477136	256	92.69	4	256	2	280	7.2e-69	226	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2904477137	355	88.67	1	347	4	316	1.1e-105	348	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2904477138	332	97.34	47	331	1	293	5.7e-55	180.9	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2904477139	576	98.16	16	571	7	540	2.3e-119	393.4	COG1178	ABC-type Fe3+ transport system, permease component	540
2904477141	231	91.38	1	220	9	220	3.8e-50	164.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
2904477142	257	98.83	1	255	1	253	1.1e-100	330.7	COG0390	ABC-type iron transport system FetAB, permease component	256
2904477143	223	93.27	5	222	3	210	1.2e-89	293.6	COG4619	ABC-type iron transport system FetAB, ATPase component	223
2904477144	513	99.79	3	489	1	481	0.0e+00	464.1	COG5339	Uncharacterized conserved protein YdgA, DUF945 family	479
2904477145	393	98.92	1	391	3	368	2.5e-129	425.7	COG1482	Mannose-6-phosphate isomerase, class I	312
2904477146	465	99.57	2	463	2	461	0.0e+00	776.7	COG0114	Fumarate hydratase class II	462
2904477149	188	97.87	4	186	3	186	5.1e-70	229.2	COG2818	3-methyladenine DNA glycosylase Tag	188
2904477150	320	96	1	320	7	318	9.9e-85	278.7	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2904477152	101	93.4	1	101	4	102	2.8e-44	144.1	COG3097	Uncharacterized protein YqfB, UPF0267 family	106
2904477153	245	66.33	1	236	2	263	6.0e-15	49.7	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2904477154	120	34.78	23	112	40	95	7.8e-06	19.6	COG3837	Uncharacterized conserved protein, cupin superfamily	161
2904477155	201	38.61	24	199	148	264	5.2e-35	115.9	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2904477156	329	96.62	1	328	9	322	3.1e-85	280.3	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2904477157	336	99.1	1	335	1	332	0.0e+00	460.8	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
2904477158	137	97.26	4	126	4	145	9.2e-14	47	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2904477159	152	90.98	21	151	11	131	3.5e-16	53.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
2904477160	69	13.07	12	69	299	344	4.3e-15	49.6	COG1566	Multidrug resistance efflux pump	352
2904477161	342	99.08	3	327	4	325	2.4e-119	392.8	COG3491	Isopenicillin N synthase and related dioxygenases	322
2904477163	293	99.3	6	290	2	285	1.8e-70	231.7	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2904477165	343	98.2	6	343	2	329	6.4e-85	279.6	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904477166	537	86.52	448	532	6	82	5.4e-26	82.4	COG1264	Phosphotransferase system IIB components	88
2904477166	537	95.95	5	447	5	407	1.7e-114	377.1	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
2904477167	391	99.22	2	391	2	384	0.0e+00	462.6	COG1168	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	388
2904477168	332	96.24	1	332	6	338	2.8e-104	343.2	COG1816	Adenosine deaminase	345
2904477169	339	97.53	1	332	2	317	2.1e-106	350	COG0385	Predicted Na+-dependent transporter	319
2904477170	348	99.15	2	346	2	349	1.3e-75	249.2	COG0673	Predicted dehydrogenase	342
2904477171	451	94.96	2	450	7	439	9.8e-88	288.9	COG2079	2-methylcitrate dehydratase PrpD	453
2904477172	300	71.64	4	277	75	266	8.5e-18	58.6	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2904477173	284	71.27	40	280	74	264	1.1e-24	81.1	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2904477174	273	96.11	1	267	6	277	7.1e-42	137.9	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904477175	254	99.17	3	253	2	241	1.2e-108	356.1	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2904477176	290	92.54	28	284	16	226	9.0e-69	225.7	COG0765	ABC-type amino acid transport system, permease component	222
2904477177	475	99.13	4	462	4	458	0.0e+00	555.7	COG0165	Argininosuccinate lyase	459
2904477178	326	97.67	26	322	2	295	1.5e-35	117.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904477179	335	94.33	10	335	11	326	1.7e-53	176.3	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2904477180	269	94.57	13	269	12	255	3.1e-73	240.7	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2904477181	256	98.01	1	253	2	247	2.0e-97	319.8	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2904477182	446	96.04	9	440	14	425	0.0e+00	477.6	COG0141	Histidinol dehydrogenase	425
2904477184	256	99.25	10	254	2	267	5.2e-70	230.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904477185	361	98.6	2	359	4	355	3.0e-64	211.3	COG0371	Glycerol dehydrogenase or related enzyme, iron-containing ADH family	360
2904477186	383	96.95	8	383	2	351	7.5e-104	341.6	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2904477187	388	99.17	22	387	2	359	4.8e-100	329.2	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2904477188	562	98.4	2	562	5	556	0.0e+00	985.2	COG2987	Urocanate hydratase	561
2904477189	516	97.99	8	506	5	492	0.0e+00	676.1	COG2986	Histidine ammonia-lyase	498
2904477190	261	97.61	3	258	4	248	8.6e-97	317.7	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2904477191	293	96.51	38	292	6	254	1.0e-70	232.3	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2904477192	326	94.03	3	326	8	322	1.7e-48	159.9	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2904477193	193	71.13	1	189	10	147	1.6e-50	166.1	COG3758	Various environmental stresses-induced protein Ves (function unknown)	193
2904477194	457	86.32	7	445	56	421	3.6e-86	283.4	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2904477195	272	97.07	32	268	5	236	2.1e-68	224.5	COG2188	DNA-binding transcriptional regulator, GntR family	236
2904477196	419	98.03	14	418	4	402	5.5e-130	428.1	COG1228	Imidazolonepropionase or related amidohydrolase	406
2904477197	279	95.59	7	273	8	267	5.6e-98	321.6	COG3741	N-formylglutamate amidohydrolase	272
2904477198	1096	19.2	372	448	36	83	2.0e-09	12.8	COG3063	Tfp pilus assembly protein PilF	250
2904477198	1096	25.6	255	347	34	97	2.0e-09	15.5	COG3063	Tfp pilus assembly protein PilF	250
2904477198	1096	26	20	128	152	216	2.0e-09	7.6	COG3063	Tfp pilus assembly protein PilF	250
2904477198	1096	26.4	355	432	38	103	2.0e-09	12.8	COG3063	Tfp pilus assembly protein PilF	250
2904477198	1096	27.6	457	546	70	138	2.0e-09	3.6	COG3063	Tfp pilus assembly protein PilF	250
2904477198	1096	28	130	254	152	221	2.0e-09	9.9	COG3063	Tfp pilus assembly protein PilF	250
2904477198	1096	36.8	573	693	12	103	2.0e-09	7.7	COG3063	Tfp pilus assembly protein PilF	250
2904477200	871	96.04	215	698	4	488	1.9e-87	288.5	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2904477201	247	98.48	1	235	2	261	4.1e-25	83.2	COG1192	Cellulose biosynthesis protein BcsQ	259
2904477206	232	92.95	1	232	8	231	3.6e-58	191.1	COG2186	DNA-binding transcriptional regulator, FadR family	241
2904477207	394	99.45	1	394	1	360	0.0e+00	533.1	COG1312	D-mannonate dehydratase	362
2904477208	311	86.36	152	299	13	126	8.7e-32	103.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904477209	334	97.49	21	333	5	315	1.6e-91	300.6	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2904477210	528	98.8	20	517	5	499	0.0e+00	641.4	COG1129	ABC-type sugar transport system, ATPase component	500
2904477212	328	96.33	1	327	10	324	2.9e-51	168.5	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2904477213	559	96.88	3	558	3	530	0.0e+00	652.1	COG1069	Ribulose kinase	544
2904477214	501	99.6	1	500	1	495	0.0e+00	828.2	COG2160	L-arabinose isomerase	497
2904477215	249	62.61	16	249	4	224	9.2e-91	299	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2904477216	333	86.05	52	329	2	260	1.2e-50	166.6	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2904477217	552	98.53	1	552	4	539	3.4e-100	330.2	COG1178	ABC-type Fe3+ transport system, permease component	540
2904477218	497	48.3	266	492	10	194	4.2e-45	19	COG0477	MFS family permease	338
2904477218	497	84.33	16	301	4	326	4.2e-45	133.4	COG0477	MFS family permease	338
2904477220	228	98.65	1	222	2	221	2.3e-61	201.5	COG0132	Dethiobiotin synthetase	223
2904477221	407	97.42	80	406	3	304	1.2e-64	212.2	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2904477222	299	97.34	4	299	2	294	3.2e-71	234.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904477223	430	48.04	252	430	8	191	2.1e-31	22.1	COG0477	MFS family permease	338
2904477223	430	72.58	44	301	2	279	2.1e-31	87.6	COG0477	MFS family permease	338
2904477224	364	99.43	1	354	1	348	0.0e+00	454.3	COG3839	ABC-type sugar transport system, ATPase component	338
2904477225	280	93.99	6	279	18	283	7.7e-83	272.3	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2904477226	307	94.3	13	305	10	290	1.8e-92	304	COG1175	ABC-type sugar transport system, permease component	295
2904477227	426	97.52	1	421	9	440	1.1e-68	226.9	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2904477228	392	97.98	7	391	7	395	2.0e-117	386.5	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2904477229	237	92.95	9	237	11	234	2.1e-51	168.9	COG2186	DNA-binding transcriptional regulator, FadR family	241
2904477230	402	93.89	10	392	4	372	1.7e-69	229.2	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2904477231	455	99.34	1	455	1	451	0.0e+00	670	COG3069	C4-dicarboxylate transporter	451
2904477232	146	10.35	8	144	824	923	3.4e-02	6.3	COG0474	Magnesium-transporting ATPase (P-type)	917
2904477233	193	99.48	1	193	1	192	1.5e-101	332.7	COG4657	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfA subunit	193
2904477234	188	93.94	1	188	3	188	1.7e-84	276.9	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
2904477235	701	98.87	11	634	2	524	0.0e+00	703.6	COG4656	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfC subunit	529
2904477236	350	99.11	2	350	2	336	0.0e+00	490.3	COG4658	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfD subunit	338
2904477237	210	97.95	2	197	3	193	1.1e-79	261.1	COG4659	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit	195
2904477238	232	99.53	1	212	1	211	2.3e-103	338.5	COG4660	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfE subunit	212
2904477239	212	98.58	1	211	1	208	2.8e-87	285.6	COG0177	Endonuclease III	211
2904477241	309	96.01	1	300	1	289	1.6e-43	143.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904477242	326	91.19	3	319	23	312	1.4e-66	219.4	COG0657	Acetyl esterase/lipase	312
2904477243	291	86.58	1	291	41	311	9.6e-101	331.4	COG2215	ABC-type nickel/cobalt efflux system, permease component RcnA	303
2904477244	90	98.88	1	89	1	88	1.1e-30	100.2	COG1937	DNA-binding transcriptional regulator, FrmR family	89
2904477245	472	97.38	24	472	2	410	0.0e+00	496.2	COG2223	Nitrate/nitrite transporter NarK	417
2904477246	596	98.78	8	590	4	570	0.0e+00	578.1	COG3850	Signal transduction histidine kinase, nitrate/nitrite-specific	574
2904477247	216	98.1	7	216	2	208	9.5e-69	225.4	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2904477250	587	97.54	1	587	6	559	1.2e-73	243.1	COG2303	Choline dehydrogenase or related flavoprotein	542
2904477251	411	18.29	6	72	54	83	3.2e-42	12.1	COG2010	Cytochrome c, mono- and diheme variants	150
2904477251	411	67.07	286	411	53	162	3.2e-42	59	COG2010	Cytochrome c, mono- and diheme variants	150
2904477251	411	99.39	110	283	1	163	3.2e-42	68.6	COG2010	Cytochrome c, mono- and diheme variants	150
2904477253	243	99.14	2	237	2	231	4.0e-67	220.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904477254	447	83.76	37	429	61	390	6.3e-59	194.6	COG0642	Signal transduction histidine kinase	336
2904477255	493	98.79	1	493	6	496	0.0e+00	655.1	COG2317	Zn-dependent carboxypeptidase, M32 family	497
2904477256	122	9.55	7	122	283	354	1.7e+00	1.6	COG0643	Chemotaxis protein histidine kinase CheA	716
2904477257	293	87.55	14	279	31	255	4.0e-57	187.7	COG3591	V8-like Glu-specific endopeptidase	251
2904477258	1291	100	18	953	1	871	0.0e+00	1069.6	COG1643	HrpA-like RNA helicase	845
2904477259	205	99.5	1	199	1	201	5.7e-76	248.6	COG1182	FMN-dependent NADH-azoreductase	202
2904477260	117	95.41	8	117	6	109	9.2e-43	139.4	COG3784	Uncharacterized conserved protein YdbL, DUF1318 family	109
2904477263	328	99.08	1	328	1	324	1.6e-102	337	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2904477264	309	61.27	40	299	29	270	1.9e-10	32.8	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2904477265	271	96.82	1	271	9	282	8.4e-70	229.7	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2904477266	303	95.3	9	302	10	293	1.3e-84	278.1	COG1175	ABC-type sugar transport system, permease component	295
2904477267	426	98.19	4	425	7	441	2.3e-62	206	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2904477268	367	99.14	1	346	1	347	7.1e-121	398	COG3839	ABC-type sugar transport system, ATPase component	338
2904477269	140	98.62	1	140	1	143	1.1e-35	116.9	COG3187	Heat shock protein HslJ	142
2904477270	93	93.1	3	93	5	85	4.5e-16	53.2	COG3042	Putative hemolysin	85
2904477271	1176	80.82	680	762	3	61	1.0e-10	34.7	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2904477271	1176	94.12	415	621	4	195	7.7e-49	159.2	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
2904477271	1176	97.32	806	1168	2	292	1.0e-104	343.9	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
2904477271	1176	99.21	1	400	3	381	5.8e-124	408.1	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
2904477273	432	72.58	7	284	12	289	2.6e-21	70.9	COG0477	MFS family permease	338
2904477274	288	76.52	157	284	25	125	7.6e-19	61.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904477275	236	94.19	6	236	7	233	2.1e-59	195	COG2186	DNA-binding transcriptional regulator, FadR family	241
2904477276	258	99.25	3	256	2	267	1.6e-61	202.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904477279	599	94.8	1	514	4	477	6.5e-55	180.5	COG0591	Na+/proline symporter	493
2904477280	81	15.33	5	76	5	27	4.3e-03	10.8	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
2904477281	77	24.39	3	74	6	35	4.3e-04	14.8	COG5633	Uncharacterized conserved protein YcfL	123
2904477282	311	82.47	17	290	1	254	1.0e-74	245.5	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
2904477285	327	91.16	12	327	30	328	4.4e-58	190.8	COG0598	Mg2+ and Co2+ transporter CorA	322
2904477286	311	97.34	10	305	3	295	3.0e-67	221.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904477287	400	95.44	10	400	12	388	1.5e-31	103.5	COG2814	Predicted arabinose efflux permease, MFS family	394
2904477288	544	98.26	9	542	9	572	0.0e+00	524.7	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2904477289	325	87.4	1	321	3	328	5.7e-66	217	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2904477290	167	99.37	2	159	2	158	7.9e-71	230.8	COG2077	Peroxiredoxin	158
2904477291	524	99.81	1	516	1	514	0.0e+00	868	COG3283	Transcriptional regulator of aromatic amino acids metabolism	511
2904477292	269	99.61	1	268	1	258	2.1e-86	283.7	COG0708	Exonuclease III	261
2904477293	131	71.51	2	128	18	140	3.0e-20	66.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2904477295	649	98.09	1	618	1	564	0.0e+00	565.6	COG0550	DNA topoisomerase IA	570
2904477296	183	89.35	1	177	3	195	8.9e-23	75.5	COG0778	Nitroreductase	207
2904477297	617	36.56	83	260	85	201	4.1e-99	21.3	COG0616	Periplasmic serine protease, ClpP class	317
2904477297	617	95.62	267	598	2	307	4.1e-99	303	COG0616	Periplasmic serine protease, ClpP class	317
2904477298	337	93.3	1	333	24	357	2.8e-107	353	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
2904477299	209	96.12	1	209	4	201	1.5e-57	188.9	COG1335	Nicotinamidase-related amidase	205
2904477300	90	97.78	1	88	1	88	2.0e-43	141	COG3139	Uncharacterized conserved protein YeaC, DUF1315 family	90
2904477301	137	88.65	2	137	8	132	1.9e-60	197	COG0229	Peptide methionine sulfoxide reductase MsrB	140
2904477302	332	98.81	2	332	1	331	0.0e+00	495.5	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
2904477303	289	98.97	3	289	2	289	1.2e-104	343.8	COG0676	D-hexose-6-phosphate mutarotase	287
2904477304	284	93.97	1	283	3	267	1.2e-86	284.3	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2904477305	249	93.8	1	249	17	258	7.3e-77	252.8	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
2904477306	644	99.85	1	644	1	649	0.0e+00	1035.1	COG2766	Predicted Ser/Thr protein kinase	649
2904477307	424	99.53	1	424	1	422	0.0e+00	683.9	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
2904477317	252	16.45	1	236	295	468	1.8e+00	.1	COG3210	Large exoprotein involved in heme utilization or adhesion	1013
2904477318	190	84.19	2	190	24	204	2.1e-70	230.6	COG1859	RNA:NAD 2'-phosphotransferase, TPT1/KptA family	211
2904477320	374	45.98	120	187	21	60	8.5e-05	15.3	COG2359	Stage V sporulation protein SpoVS  (function unknown)	87
2904477322	131	33.18	33	129	31	102	2.6e-03	11.6	COG1777	Predicted transcriptional regulator	217
2904477324	540	96.07	1	540	19	556	0.0e+00	454.8	COG2831	Hemolysin activation/secretion protein	554
2904477325	254	96.56	2	254	10	262	1.0e-93	307.9	COG3137	Putative salt-induced outer membrane protein YdiY	262
2904477326	276	97.45	15	276	3	269	1.5e-83	274.5	COG0171	NH3-dependent NAD+ synthetase	268
2904477328	398	48.3	198	396	8	192	5.5e-31	12.3	COG0477	MFS family permease	338
2904477328	398	69.19	1	225	3	267	5.5e-31	93.6	COG0477	MFS family permease	338
2904477329	357	99.45	1	357	2	363	1.2e-119	393.7	COG0787	Alanine racemase	360
2904477330	433	96.91	1	424	5	380	8.3e-92	302.5	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2904477333	276	97.29	6	276	7	293	3.9e-48	158.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904477334	511	98.19	7	511	6	492	0.0e+00	816.5	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
2904477335	240	98.34	1	233	1	237	3.3e-70	230.5	COG2186	DNA-binding transcriptional regulator, FadR family	241
2904477336	525	99.61	1	516	1	514	0.0e+00	939.7	COG3067	Na+/H+ antiporter NhaB	516
2904477337	176	98.27	1	168	1	170	3.8e-50	164.5	COG1495	Disulfide bond formation protein DsbB	170
2904477339	369	93.61	2	358	15	351	1.1e-62	206.2	COG0628	Predicted PurR-regulated permease PerM	355
2904477342	305	93.04	1	303	3	336	5.3e-41	135.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2904477344	250	83.1	16	248	41	276	1.1e-47	156.8	COG2801	Transposase InsO and inactivated derivatives	232
2904477346	84	64.96	1	82	7	82	2.0e-06	20.5	COG2963	Transposase and inactivated derivatives	116
2904477347	149	96.08	1	149	6	152	3.0e-69	226	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
2904477348	218	75.09	2	216	57	261	1.0e-75	248.9	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2904477349	391	95.97	13	365	13	345	3.3e-114	375.9	COG2951	Membrane-bound lytic murein transglycosylase B	343
2904477350	87	81.55	1	87	14	97	2.2e-41	134.3	COG3100	Uncharacterized conserved protein YcgL, UPF0745 family	103
2904477351	194	86.03	1	194	32	228	1.2e-62	206.2	COG0850	Septum formation inhibitor MinC	219
2904477352	270	98.53	1	270	1	268	0.0e+00	453.5	COG2894	Septum formation inhibitor-activating ATPase MinD	272
2904477353	89	97.73	1	89	1	86	6.6e-37	119.7	COG0851	Septum formation topological specificity factor MinE	88
2904477354	373	99.72	6	372	1	361	6.2e-130	427.8	COG0349	Ribonuclease D	361
2904477355	565	97.71	14	563	6	560	0.0e+00	498.8	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2904477356	210	97.38	13	209	5	190	5.5e-67	218.7	COG3065	Starvation-inducible outer membrane lipoprotein	191
2904477357	233	99.1	3	230	2	220	6.5e-75	246.2	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
2904477358	637	98.97	5	636	3	673	0.0e+00	619.5	COG1199	Rad3-related DNA helicase	654
2904477359	114	91.91	1	114	9	133	4.7e-23	75.8	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2904477360	213	99.05	3	213	2	210	1.4e-85	280.2	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
2904477361	491	99.18	3	490	3	484	0.0e+00	678.6	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
2904477362	294	99.29	4	283	2	281	6.2e-96	315	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2904477363	480	99.79	2	479	2	478	0.0e+00	603.3	COG0469	Pyruvate kinase	477
2904477364	522	88.98	49	519	43	454	1.8e-110	363.6	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
2904477365	436	97.94	5	433	3	429	0.0e+00	520.8	COG3486	Lysine/ornithine N-monooxygenase	436
2904477366	794	78.61	16	183	18	164	2.2e-11	37.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2904477366	794	98.67	198	792	8	601	0.0e+00	564.8	COG4264	Siderophore synthetase component	602
2904477367	406	47.78	215	406	13	195	9.5e-29	11.4	COG0477	MFS family permease	338
2904477367	406	62.66	12	242	7	246	9.5e-29	87.3	COG0477	MFS family permease	338
2904477368	326	99.03	12	318	3	307	8.8e-103	337.9	COG1560	Lauroyl/myristoyl acyltransferase	308
2904477369	423	98.1	80	409	3	312	4.7e-71	234.4	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2904477370	329	99.39	19	329	2	326	0.0e+00	433.2	COG4531	ABC-type Zn2+ transport system, periplasmic component/surface adhesin	318
2904477371	252	98.82	1	236	4	254	3.5e-85	279.6	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
2904477372	261	93.84	1	261	12	270	1.8e-84	277.6	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2904477373	443	34.4	300	443	279	428	9.6e-63	68	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
2904477373	443	55.96	1	260	20	263	9.6e-63	143.9	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
2904477377	229	90.87	5	228	6	224	9.8e-61	199.3	COG2186	DNA-binding transcriptional regulator, FadR family	241
2904477378	336	99.1	2	333	1	331	1.2e-121	400.2	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904477379	309	99.68	5	308	1	315	2.9e-86	283.6	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2904477380	296	94.5	1	296	3	311	1.3e-90	297.8	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2904477381	323	96.55	9	323	5	312	4.1e-114	375	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2904477382	501	98.8	1	494	6	500	0.0e+00	669.1	COG1129	ABC-type sugar transport system, ATPase component	500
2904477383	139	100	1	139	1	135	1.1e-59	194.6	COG1869	D-ribose pyranose/furanose isomerase RbsD	135
2904477384	622	98.88	1	622	8	627	0.0e+00	929.8	COG3158	K+ transporter	627
2904477385	502	95.15	1	320	6	319	5.4e-70	229.8	COG0714	MoxR-like ATPase	329
2904477386	489	99.78	16	488	2	448	0.0e+00	475.1	COG2425	Uncharacterized protein, contains a von Willebrand factor type A (vWA) domain	437
2904477387	153	92.41	3	152	5	150	3.3e-37	122.1	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2904477388	147	98.69	1	146	1	151	1.5e-32	107.3	COG0716	Flavodoxin	151
2904477389	629	99.2	3	626	2	620	0.0e+00	999.9	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
2904477390	206	97.67	1	206	2	211	3.0e-75	246.6	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
2904477391	132	95.31	6	132	6	127	7.3e-40	130.3	COG3312	FoF1-type ATP synthase assembly protein I	128
2904477392	260	98.41	2	260	5	252	1.8e-94	310.1	COG0356	FoF1-type ATP synthase, membrane subunit a	246
2904477393	79	97.5	1	79	2	79	1.7e-23	76.9	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
2904477394	135	83.85	1	135	24	158	2.7e-44	144.9	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2904477395	177	100	1	176	1	178	3.6e-62	203.7	COG0712	FoF1-type ATP synthase, delta subunit	178
2904477396	513	99.4	1	513	1	501	0.0e+00	810.6	COG0056	FoF1-type ATP synthase, alpha subunit	504
2904477397	287	99.65	5	287	1	287	4.4e-118	388.4	COG0224	FoF1-type ATP synthase, gamma subunit	287
2904477398	460	99.15	1	460	1	464	0.0e+00	813.7	COG0055	FoF1-type ATP synthase, beta subunit	468
2904477399	140	99.26	1	136	1	134	1.6e-49	161.5	COG0355	FoF1-type ATP synthase, epsilon subunit	135
2904477400	456	99.13	4	456	3	457	0.0e+00	653.3	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
2904477401	609	100	1	609	1	615	0.0e+00	798.5	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
2904477402	290	99.19	5	239	2	245	4.5e-73	239.6	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2904477403	346	96	1	326	13	324	5.3e-94	309.3	COG0226	ABC-type phosphate transport system, periplasmic component	318
2904477404	318	95.86	2	316	13	313	1.6e-114	376.2	COG0573	ABC-type phosphate transport system, permease component	310
2904477405	295	97.28	12	295	4	289	2.8e-104	342.5	COG0581	ABC-type phosphate transport system, permease component	292
2904477406	255	98.82	2	255	4	254	1.3e-125	412	COG1117	ABC-type phosphate transport system, ATPase component	253
2904477407	243	97.96	1	239	2	241	8.7e-74	242.2	COG0704	Phosphate uptake regulator	240
2904477408	230	81.34	20	227	13	182	1.2e-13	46.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904477409	258	92.45	1	251	17	273	4.0e-47	155.1	COG1082	Sugar phosphate isomerase/epimerase	274
2904477410	221	98.19	3	216	2	218	1.6e-49	162.9	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2904477411	445	99.32	10	443	3	442	0.0e+00	571.9	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
2904477412	189	96.2	6	188	2	178	6.7e-58	189.6	COG0431	NAD(P)H-dependent FMN reductase	184
2904477413	241	81.17	1	215	33	213	2.9e-24	79.8	COG2091	Phosphopantetheinyl transferase	223
2904477414	631	81.88	137	631	78	425	2.3e-105	347.7	COG0840	Methyl-accepting chemotaxis protein	408
2904477415	295	97.67	2	295	2	295	5.0e-68	224.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904477416	199	81.34	1	198	7	224	8.1e-17	53.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904477417	454	99.78	1	454	2	454	0.0e+00	574.3	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
2904477418	544	98.1	246	544	2	310	3.0e-110	363.1	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
2904477419	85	80.43	4	85	7	80	6.8e-36	115.2	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
2904477420	108	90.68	1	108	7	113	1.7e-35	116	COG0594	RNase P protein component	117
2904477421	46	100	1	44	1	44	2.6e-27	88.9	COG0230	Ribosomal protein L34	44
2904477422	463	100	6	459	1	433	0.0e+00	643.1	COG0593	Chromosomal replication initiation ATPase DnaA	408
2904477424	366	100	1	366	1	365	0.0e+00	448.3	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
2904477425	362	99.72	1	358	1	362	1.3e-124	410.2	COG1195	Recombinational DNA repair ATPase RecF	363
2904477426	804	99.69	1	804	3	641	0.0e+00	1000.6	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
2904477427	271	99.63	1	270	1	271	3.1e-74	244.3	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
2904477429	125	83.75	1	86	9	75	7.3e-27	87.4	COG5645	Uncharacterized conserved protein YceK	80
2904477430	136	94.52	1	136	8	145	1.6e-37	122.8	COG0071	Molecular chaperone IbpA, HSP20 family	146
2904477432	144	94.52	1	133	8	145	4.4e-29	95.5	COG0071	Molecular chaperone IbpA, HSP20 family	146
2904477434	416	99.52	1	416	1	415	0.0e+00	753.3	COG3977	Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase	417
2904477436	325	99.69	1	320	1	326	2.0e-105	346.5	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2904477437	430	91.78	3	423	26	438	3.4e-39	129	COG2271	Sugar phosphate permease	448
2904477438	249	18.35	12	105	19	69	3.0e-08	6.2	COG1082	Sugar phosphate isomerase/epimerase	274
2904477438	249	25.54	118	246	171	241	3.0e-08	19.9	COG1082	Sugar phosphate isomerase/epimerase	274
2904477439	344	99.4	13	344	1	332	1.2e-81	268.8	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904477440	428	52.22	228	425	8	207	1.5e-14	23.2	COG0477	MFS family permease	338
2904477440	428	52.48	15	242	3	203	1.5e-14	29.3	COG0477	MFS family permease	338
2904477441	708	98.84	2	693	2	681	0.0e+00	721.5	COG3345	Alpha-galactosidase	687
2904477442	335	99.1	1	335	2	332	4.8e-74	243.8	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904477443	220	92.96	23	219	14	198	3.4e-55	181.6	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2904477444	147	60.32	1	126	51	164	2.6e-08	26.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2904477445	190	98.4	3	189	2	186	8.5e-85	277.3	COG2818	3-methyladenine DNA glycosylase Tag	188
2904477446	668	93.87	8	398	17	368	7.9e-73	239.8	COG3240	Phospholipase/lecithinase/hemolysin	370
2904477446	668	99.58	426	668	2	239	3.1e-66	217.4	COG5571	Uncharacterized protein YhjY, contains autotransporter beta-barrel domain	239
2904477447	82	70.93	4	80	2	62	2.5e-09	31.1	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
2904477448	94	95.6	1	90	1	87	2.6e-22	73.1	COG2026	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system	90
2904477449	311	98.99	3	302	3	297	0.0e+00	552.5	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
2904477450	689	99.86	1	689	1	690	0.0e+00	929.1	COG0751	Glycyl-tRNA synthetase, beta subunit	691
2904477452	264	98.39	5	262	4	248	2.6e-33	109.8	COG1651	Protein-disulfide isomerase	244
2904477454	514	90.42	200	474	7	157	4.2e-49	159.9	COG2131	Deoxycytidylate deaminase	164
2904477455	637	97.18	496	637	2	139	1.1e-56	183.8	COG4668	Mannitol/fructose-specific phosphotransferase system, IIA domain	142
2904477455	637	98.94	1	471	3	470	0.0e+00	790.3	COG2213	Phosphotransferase system, mannitol-specific IIBC component	472
2904477456	382	92.62	1	382	17	455	2.5e-109	360.4	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
2904477457	182	98.28	1	176	2	172	1.4e-81	266.7	COG3722	DNA-binding transcriptional regulator, MltR family	174
2904477459	202	95.67	3	197	8	206	2.7e-38	125.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2904477460	499	98.46	8	481	4	452	1.1e-116	384.5	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2904477462	223	97.2	1	211	4	211	2.0e-67	221.2	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
2904477463	648	91.53	192	612	37	425	2.7e-113	373.9	COG0840	Methyl-accepting chemotaxis protein	408
2904477464	206	98.05	1	206	2	202	6.8e-82	268.6	COG0605	Superoxide dismutase	204
2904477465	280	94.76	16	280	13	265	1.7e-95	313.5	COG1526	Formate dehydrogenase assembly factor FdhD	266
2904477466	1015	99.88	2	1015	1	809	0.0e+00	687	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2904477467	303	96.59	18	240	5	202	1.4e-61	201.8	COG0437	Fe-S-cluster-containing dehydrogenase component	203
2904477468	217	98.17	1	215	1	214	1.6e-86	283.6	COG2864	Cytochrome b subunit of formate dehydrogenase	218
2904477469	304	99.35	1	304	1	306	4.6e-120	395	COG3058	Formate dehydrogenase maturation protein FdhE	308
2904477470	213	94.88	1	207	1	204	2.2e-39	129.7	COG0625	Glutathione S-transferase	211
2904477471	512	99.37	25	507	2	477	0.0e+00	591.7	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2904477472	412	96.34	12	407	7	375	5.1e-28	91.8	COG0477	MFS family permease	338
2904477473	331	99.7	1	331	1	331	2.6e-107	352.9	COG3274	Surface polysaccharide O-acyltransferase, integral membrane enzyme	332
2904477474	304	91.38	1	302	7	303	2.9e-69	227.7	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2904477475	184	38.35	1	80	4	82	9.7e-27	21.8	COG1335	Nicotinamidase-related amidase	205
2904477475	184	41.26	63	172	104	188	9.7e-27	67.9	COG1335	Nicotinamidase-related amidase	205
2904477476	198	97.96	6	179	2	193	9.3e-26	85.1	COG0693	Putative intracellular protease/amidase	188
2904477477	343	98.58	5	343	5	352	1.9e-78	257.9	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2904477478	400	95.78	1	394	15	400	0.0e+00	487.3	COG3135	Predicted benzoate:H+ symporter BenE	402
2904477479	188	56.49	65	183	33	106	1.9e-08	28	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2904477479	188	79.71	3	69	5	59	3.0e-08	27.1	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2904477480	150	80.86	8	149	21	151	6.9e-13	43.3	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904477481	160	50.79	10	159	76	171	7.8e-15	49.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2904477483	159	98.1	1	159	1	155	1.6e-35	116.6	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2904477486	209	93.02	6	208	8	207	2.1e-37	123.2	COG0625	Glutathione S-transferase	211
2904477487	148	53.09	7	124	67	152	5.0e-11	37.5	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904477488	211	98.08	2	211	4	207	4.6e-57	186.7	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2904477490	82	97.56	1	82	1	80	3.4e-29	95.2	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
2904477493	232	94.94	1	229	3	227	6.1e-91	297.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2904477494	265	97.66	13	265	4	253	7.8e-126	412.8	COG4674	ABC-type uncharacterized transport system, ATPase component	249
2904477495	357	94.12	15	357	18	321	9.0e-92	301.8	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2904477496	522	98.34	222	521	4	299	1.1e-98	324.6	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2904477497	422	98.36	14	396	5	364	2.3e-76	251.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2904477498	240	92.67	4	225	8	222	6.0e-51	167.2	COG1802	DNA-binding transcriptional regulator, GntR family	230
2904477499	1209	22.14	1026	1207	501	643	0.0e+00	63.8	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2904477499	1209	68.42	1	449	1	442	0.0e+00	616.5	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2904477499	1209	97.47	449	777	1	308	2.3e-99	326.1	COG1984	Allophanate hydrolase subunit 2	314
2904477500	616	96.67	12	464	9	473	1.2e-104	345	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2904477502	97	96.97	1	96	1	96	3.4e-17	57.2	COG3668	Plasmid stabilization system protein ParE	98
2904477503	481	95.13	69	437	4	296	2.7e-61	201.3	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2904477504	152	82.71	25	151	5	114	3.7e-28	92.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
2904477505	140	97.9	1	140	4	143	4.0e-49	160.7	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2904477506	556	97.48	1	556	9	550	0.0e+00	532.3	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
2904477509	114	76.92	10	103	5	74	9.3e-12	39.4	COG2002	Bifunctional DNA-binding transcriptional regulator of stationary/sporulation/toxin gene expression and antitoxin component of the YhaV-PrlF toxin-antitoxin module	89
2904477511	459	95.61	1	451	10	445	1.7e-65	215.5	COG2079	2-methylcitrate dehydratase PrpD	453
2904477512	260	96.86	14	260	2	248	3.4e-91	299.4	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
2904477513	288	83.38	5	281	1	271	3.0e-101	332.8	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2904477514	311	94.97	25	311	12	294	8.4e-101	331	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904477515	361	98.11	24	360	6	317	9.2e-108	354.5	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904477516	532	95.33	2	532	18	568	6.2e-81	267.2	COG0747	ABC-type transport system, periplasmic component	556
2904477517	479	97.96	8	451	8	392	6.9e-89	292.7	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2904477518	308	97.67	1	307	1	294	7.1e-45	148.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904477519	535	95.85	1	535	18	571	0.0e+00	493.7	COG0747	ABC-type transport system, periplasmic component	556
2904477520	339	99.69	1	339	1	317	1.2e-130	429.8	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904477521	304	95.64	12	304	12	296	1.4e-105	346.7	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904477522	341	99.08	15	331	1	322	4.3e-128	421	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2904477523	340	97.81	8	319	2	314	3.0e-122	402	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2904477524	202	92.79	4	202	9	201	7.4e-30	98.4	COG2184	Fido, protein-threonine AMPylation domain	201
2904477525	155	60	30	149	6	83	8.6e-15	49.7	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2904477526	337	91.11	1	336	13	340	1.4e-65	215.6	COG3405	Endo-1,4-beta-D-glucanase Y	360
2904477528	1320	20.4	677	751	47	97	7.4e-12	21	COG3063	Tfp pilus assembly protein PilF	250
2904477528	1320	26.4	264	434	42	107	7.4e-12	16.1	COG3063	Tfp pilus assembly protein PilF	250
2904477528	1320	27.2	3	110	27	94	7.4e-12	9	COG3063	Tfp pilus assembly protein PilF	250
2904477528	1320	28.8	536	632	20	91	7.4e-12	3.8	COG3063	Tfp pilus assembly protein PilF	250
2904477528	1320	39.6	381	560	130	228	7.4e-12	6.5	COG3063	Tfp pilus assembly protein PilF	250
2904477531	699	94.46	70	534	4	480	4.3e-78	257.7	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2904477532	267	96.21	1	252	3	256	1.6e-27	91.2	COG1192	Cellulose biosynthesis protein BcsQ	259
2904477534	646	30.05	205	271	7	61	7.0e-10	4.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904477534	646	52.46	279	382	88	183	7.0e-10	25.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904477534	646	95.33	393	646	4	248	1.7e-72	237.2	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2904477535	427	97.13	2	425	3	408	0.0e+00	540.4	COG1301	Na+/H+-dicarboxylate symporter	415
2904477536	504	91.99	19	468	6	407	4.2e-65	214	COG0612	Predicted Zn-dependent peptidase	438
2904477537	312	95.57	5	309	1	302	3.7e-68	224	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2904477538	67	94.2	1	67	1	65	4.4e-30	97.5	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2904477539	258	90.27	17	257	17	248	5.5e-35	114.7	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2904477540	684	100	1	675	1	677	0.0e+00	741.9	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2904477541	256	99.21	1	252	1	250	8.3e-104	340.5	COG2134	CDP-diacylglycerol pyrophosphatase	252
2904477542	440	48.3	242	438	9	193	9.6e-43	44	COG0477	MFS family permease	338
2904477542	440	66.32	20	299	4	257	9.6e-43	100.8	COG0477	MFS family permease	338
2904477543	374	98.02	32	346	4	300	2.8e-71	234.3	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2904477544	299	96.68	2	296	3	293	1.1e-73	242.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904477545	252	98.88	1	252	3	267	1.7e-56	186.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904477546	248	97.42	2	245	5	231	1.2e-56	185.8	COG5581	c-di-GMP-binding flagellar brake protein YcgR, contains PilZNR and PilZ domains	233
2904477547	192	97.24	6	190	5	180	3.5e-45	147.9	COG3038	Cytochrome b561	181
2904477548	180	26.63	20	162	237	334	1.1e-08	30	COG0457	Tetratricopeptide (TPR) repeat	291
2904477549	151	76.88	2	148	37	179	4.1e-32	105.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2904477550	258	96.5	6	258	8	255	2.0e-12	41.5	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2904477551	549	99.53	25	499	2	429	0.0e+00	505.6	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
2904477552	550	99.77	25	499	2	430	0.0e+00	479.5	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
2904477553	483	89.02	1	451	49	486	1.6e-39	130	COG0531	Amino acid transporter	466
2904477554	150	95.45	1	148	2	148	4.1e-31	101.9	COG2731	Beta-galactosidase, beta subunit	154
2904477555	1018	98.45	28	885	12	837	0.0e+00	786.1	COG3250	Beta-galactosidase/beta-glucuronidase	808
2904477556	349	99.1	25	349	1	331	2.2e-76	251	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904477559	417	90.18	1	413	12	415	3.2e-63	208	COG1457	Purine-cytosine permease or related protein	442
2904477560	223	76.49	4	208	43	234	3.2e-31	102	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2904477561	717	99.27	37	717	5	682	0.0e+00	840.9	COG0339	Zn-dependent oligopeptidase	683
2904477562	352	98.21	183	347	3	167	7.0e-52	170.2	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2904477562	352	99.47	1	187	1	188	4.1e-65	213.1	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
2904477563	250	85.91	1	250	3	252	7.6e-62	203.4	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
2904477564	401	36.81	216	400	59	199	2.4e-21	12.9	COG0477	MFS family permease	338
2904477564	401	79.9	2	279	4	309	2.4e-21	60.1	COG0477	MFS family permease	338
2904477566	361	98.08	1	361	3	360	0.0e+00	435	COG4748	Uncharacterized protein	365
2904477567	233	90.43	23	230	5	193	8.5e-25	82.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904477568	499	50.39	270	498	2	194	5.6e-51	23.7	COG0477	MFS family permease	338
2904477568	499	71.54	17	271	4	277	5.6e-51	150.6	COG0477	MFS family permease	338
2904477569	615	98.65	23	610	8	591	0.0e+00	462.8	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2904477570	375	97.42	1	374	10	386	0.0e+00	506.6	COG3146	Predicted N-acyltransferase	387
2904477571	211	96.63	1	204	4	204	2.5e-64	211.1	COG0288	Carbonic anhydrase	207
2904477572	180	89.08	1	169	6	160	4.0e-61	200.3	COG0225	Peptide methionine sulfoxide reductase MsrA	174
2904477573	60	85.51	1	60	1	59	5.2e-19	62.1	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2904477574	101	15.76	3	100	229	286	4.9e-04	15	COG0457	Tetratricopeptide (TPR) repeat	291
2904477575	421	90.68	1	421	7	444	1.2e-115	381.2	COG3037	Ascorbate-specific PTS system EIIC-type component UlaA	481
2904477576	100	98.92	3	94	2	93	5.6e-21	69.2	COG3414	Phosphotransferase system, galactitol-specific IIB component	93
2904477577	124	81.58	1	124	25	148	5.2e-33	108.3	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
2904477578	198	18.39	15	158	253	309	5.6e-06	19.9	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2904477579	311	98.04	2	301	2	301	1.4e-94	310.8	COG3684	Tagatose-1,6-bisphosphate aldolase	306
2904477580	310	95.62	2	307	12	317	1.0e-68	225.8	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
2904477582	971	52.72	476	620	34	159	4.7e-05	3.5	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2904477582	971	53.56	258	411	26	153	4.7e-05	12.5	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2904477582	971	53.56	604	745	15	142	4.7e-05	3.3	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2904477582	971	53.97	112	267	24	152	4.7e-05	17.4	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2904477582	971	55.65	556	702	16	148	4.7e-05	5.1	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2904477582	971	59.41	410	568	15	156	4.7e-05	4.5	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2904477582	971	98.54	761	969	4	206	1.8e-21	71.5	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
2904477583	273	98.64	1	273	3	293	1.8e-49	163.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904477584	213	96.6	7	203	1	199	2.5e-24	80.5	COG1335	Nicotinamidase-related amidase	205
2904477585	139	79.17	11	135	14	127	1.2e-22	75	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2904477586	528	49.61	225	456	11	200	1.0e-20	20.7	COG0477	MFS family permease	338
2904477586	528	71.54	14	286	4	277	1.0e-20	56.7	COG0477	MFS family permease	338
2904477587	302	97.01	3	296	2	293	4.9e-53	175.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904477588	102	38.97	3	95	8	83	4.1e-20	66.1	COG3224	Antibiotic biosynthesis monooxygenase (ABM) superfamily enzyme	195
2904477589	283	32.61	15	213	3	197	6.7e-28	91.8	COG0322	Excinuclease UvrABC, nuclease subunit	581
2904477591	450	99.78	1	450	1	454	0.0e+00	495.7	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2904477593	292	100	14	292	1	279	0.0e+00	450.1	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
2904477594	692	99.27	1	692	5	682	0.0e+00	991.5	COG0339	Zn-dependent oligopeptidase	683
2904477596	146	98.11	1	141	3	158	7.2e-25	83	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2904477598	501	99.15	12	501	3	353	0.0e+00	447	COG0306	Phosphate/sulfate permease	326
2904477599	399	99.26	1	398	2	405	0.0e+00	554.6	COG2081	Predicted flavoprotein YhiN	408
2904477602	78	45.57	1	78	82	153	2.6e-14	47.8	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2904477604	551	90.59	29	512	40	424	1.0e-99	328.9	COG0840	Methyl-accepting chemotaxis protein	408
2904477606	403	88.61	1	379	18	375	1.3e-44	147.3	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2904477607	568	43.69	269	466	63	190	1.1e-41	32.2	COG3176	Putative hemolysin	292
2904477607	568	69.62	45	265	65	268	1.1e-41	103	COG3176	Putative hemolysin	292
2904477608	408	50.39	215	406	10	202	7.8e-19	25.1	COG0477	MFS family permease	338
2904477608	408	71.54	15	247	4	277	7.8e-19	40.5	COG0477	MFS family permease	338
2904477609	169	90.37	1	165	12	180	4.4e-20	66.8	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2904477613	231	88.57	1	231	1	248	1.1e-71	236	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2904477615	107	98.04	1	102	1	100	3.4e-37	121	COG1440	Phosphotransferase system cellobiose-specific component IIB	102
2904477616	442	98.39	5	434	4	430	0.0e+00	432.3	COG1455	Phosphotransferase system cellobiose-specific component IIC	432
2904477617	460	98.7	2	460	2	458	0.0e+00	569.5	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2904477618	305	92.81	2	304	1	310	9.9e-51	167.2	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904477619	333	97.9	8	333	3	329	6.7e-93	305.9	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904477620	171	98.76	9	170	1	159	2.9e-71	232.5	COG3265	Gluconate kinase	161
2904477621	438	99.78	1	438	2	449	0.0e+00	539.9	COG2610	H+/gluconate symporter or related permease	442
2904477622	110	83.52	8	96	8	83	7.3e-05	17.1	COG2026	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system	90
2904477623	96	72.12	2	91	26	100	2.7e-21	69.7	COG2944	DNA-binding transcriptional regulator YiaG, XRE-type HTH domain	104
2904477624	197	97.07	1	197	5	203	1.2e-65	215.1	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
2904477625	367	99.7	1	367	1	335	7.5e-115	378.2	COG0136	Aspartate-semialdehyde dehydrogenase	334
2904477626	727	14.38	5	103	17	107	0.0e+00	1.9	COG0296	1,4-alpha-glucan branching enzyme	628
2904477626	727	99.68	100	725	2	632	0.0e+00	858.3	COG0296	1,4-alpha-glucan branching enzyme	628
2904477627	674	97.73	1	671	11	698	0.0e+00	798.8	COG1523	Pullulanase/glycogen debranching enzyme	697
2904477628	425	97.45	15	425	5	386	0.0e+00	526.7	COG0448	ADP-glucose pyrophosphorylase	393
2904477629	478	98.57	1	478	1	482	0.0e+00	575.8	COG0297	Glycogen synthase	487
2904477630	815	99.6	7	812	4	752	0.0e+00	1013.4	COG0058	Glucan phosphorylase	750
2904477631	503	94.79	2	502	12	520	0.0e+00	622	COG0578	Glycerol-3-phosphate dehydrogenase	532
2904477632	252	98.03	1	252	2	250	9.1e-90	294.9	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2904477633	277	93.42	60	277	3	215	7.6e-37	121.6	COG0705	Membrane associated serine protease, rhomboid family	228
2904477637	396	98.24	5	396	5	394	0.0e+00	449.2	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2904477638	106	91.23	1	104	3	106	3.5e-24	79.4	COG0607	Rhodanese-related sulfurtransferase	110
2904477639	251	99.21	1	251	1	252	5.8e-70	230	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2904477640	354	99.62	31	332	2	265	3.4e-94	309.3	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
2904477641	467	99.17	1	465	1	479	0.0e+00	604.2	COG3037	Ascorbate-specific PTS system EIIC-type component UlaA	481
2904477642	102	97.85	2	94	2	92	3.0e-31	102.2	COG3414	Phosphotransferase system, galactitol-specific IIB component	93
2904477643	156	95.39	3	153	3	147	3.1e-43	141.3	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
2904477644	218	98.62	3	218	3	216	3.1e-87	285.9	COG0269	3-keto-L-gulonate-6-phosphate decarboxylase	217
2904477645	286	98.61	1	282	3	285	0.0e+00	460.1	COG3623	L-ribulose-5-phosphate 3-epimerase UlaE	287
2904477646	229	97.32	1	229	6	223	2.3e-70	231	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2904477647	804	98.8	2	804	9	751	0.0e+00	925.4	COG0058	Glucan phosphorylase	750
2904477648	691	99.43	131	691	1	526	0.0e+00	629.6	COG1640	4-alpha-glucanotransferase	520
2904477649	191	88.42	1	92	3	86	1.8e-03	12.4	COG4841	Uncharacterized protein YneR	95
2904477649	191	98.92	98	189	1	92	2.9e-32	104	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
2904477650	229	97.32	1	227	6	223	5.6e-72	236.3	COG1040	Predicted amidophosphoribosyltransferases	225
2904477651	260	91.86	2	256	22	292	1.2e-33	111.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904477654	285	96.9	13	284	4	284	2.3e-52	171.2	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
2904477656	280	79.93	3	252	53	287	3.7e-59	194.4	COG0777	Acetyl-CoA carboxylase beta subunit	294
2904477658	320	98.4	1	318	1	308	2.9e-41	135.7	COG0679	Predicted permease	311
2904477660	311	92.65	1	293	3	317	3.3e-43	141.7	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
2904477663	306	97.01	6	305	2	293	2.5e-47	156.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904477665	772	99.69	1	721	1	652	0.0e+00	873.3	COG0370	Fe2+ transport system protein B	653
2904477666	74	93.33	1	74	4	73	4.1e-22	72.5	COG1918	Fe2+ transport system protein FeoA	75
2904477667	776	98.98	1	775	6	779	0.0e+00	1139.2	COG2183	Transcriptional accessory protein Tex/SPT6	780
2904477668	157	99.34	6	156	1	151	4.0e-54	177.1	COG0782	Transcription elongation factor, GreA/GreB family	151
2904477669	2005	99.76	277	1997	2	1630	0.0e+00	1490.1	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
2904477670	789	99.32	12	787	5	733	0.0e+00	752.6	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
2904477671	371	92.51	177	371	13	185	1.6e-20	67.7	COG3539	Pilin (type 1 fimbria component protein)	184
2904477672	836	98.57	10	836	12	837	0.0e+00	945.8	COG3188	Outer membrane usher protein FimD/PapC	835
2904477673	228	95.82	1	227	9	237	1.6e-74	244.5	COG3121	P pilus assembly protein, chaperone PapD	235
2904477674	182	98.4	1	182	4	187	2.5e-30	100.1	COG3539	Pilin (type 1 fimbria component protein)	184
2904477676	239	99.14	5	236	1	230	2.5e-85	279.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904477677	453	81.73	6	443	68	389	2.2e-54	178.8	COG0642	Signal transduction histidine kinase	336
2904477678	159	97.73	1	140	2	130	2.1e-13	45	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
2904477679	70	52.5	1	70	1	42	4.3e-18	60.1	COG4691	Plasmid stability protein	80
2904477680	540	98.68	4	540	7	528	0.0e+00	851.6	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
2904477681	294	99.65	1	280	1	286	1.4e-107	353.6	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
2904477682	134	95	1	105	4	98	9.4e-37	119.8	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
2904477683	229	97.4	7	222	4	228	7.2e-31	102.1	COG1011	FMN phosphatase YigB, HAD superfamily	229
2904477686	185	84.3	33	180	12	156	6.1e-17	56.3	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2904477687	851	97.86	1	850	2	779	0.0e+00	1110	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
2904477689	187	87.98	1	184	4	186	1.7e-13	44.8	COG3166	Tfp pilus assembly protein PilN	206
2904477691	420	60.42	4	419	282	713	1.8e-126	417.4	COG4796	Type II secretory pathway, component HofQ	709
2904477692	161	91.86	1	161	11	168	7.1e-60	196.2	COG0703	Shikimate kinase	172
2904477693	360	99.17	1	360	1	357	0.0e+00	480.8	COG0337	3-dehydroquinate synthetase	360
2904477694	349	99.34	28	348	3	302	6.3e-80	263.5	COG3266	Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain	292
2904477695	271	98.56	3	271	2	274	3.7e-97	319.2	COG0338	Site-specific DNA-adenine methylase	274
2904477696	225	99.09	1	222	1	218	1.5e-93	306.2	COG0036	Pentose-5-phosphate-3-epimerase	220
2904477697	232	95.5	7	225	9	220	1.8e-64	212	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2904477698	338	99.05	1	316	4	317	1.8e-115	379.8	COG0180	Tryptophanyl-tRNA synthetase	314
2904477699	464	97.63	1	210	1	206	2.6e-65	213.6	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
2904477699	464	99.18	213	455	2	243	1.7e-102	336.2	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2904477700	116	98.13	1	109	2	106	2.9e-23	76.1	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2904477701	850	100	1	810	1	801	0.0e+00	1163.7	COG1251	NAD(P)H-nitrite reductase, large subunit	793
2904477702	427	94.58	2	425	14	414	7.8e-99	325.2	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2904477703	188	98.09	28	188	2	155	1.2e-54	178.9	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
2904477704	507	86.22	20	446	3	465	2.2e-99	327.9	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
2904477707	200	97.12	1	200	3	204	4.7e-56	184.1	COG2184	Fido, protein-threonine AMPylation domain	201
2904477708	191	97.91	1	191	3	189	7.6e-80	261.2	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
2904477709	405	97.04	1	404	7	399	0.0e+00	556.7	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2904477710	691	99.56	3	688	2	684	0.0e+00	507.6	COG1289	Uncharacterized membrane protein YccC	674
2904477711	210	93.12	6	210	16	218	1.1e-54	179.5	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2904477712	135	97.81	1	133	2	135	2.5e-47	154.6	COG1765	Uncharacterized OsmC-related protein	137
2904477713	289	100	1	289	1	289	0.0e+00	583.2	COG3954	Phosphoribulokinase	289
2904477714	304	96.01	2	294	4	292	3.8e-51	168.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904477715	168	90.48	1	161	3	154	4.2e-63	206	COG3194	Ureidoglycolate hydrolase (allantoin degradation)	168
2904477716	269	99.59	22	267	1	245	2.1e-80	263.5	COG1414	DNA-binding transcriptional regulator, IclR family	246
2904477717	593	100	1	592	1	592	0.0e+00	1210.3	COG3960	Glyoxylate carboligase	592
2904477718	258	99.23	1	258	1	258	1.7e-120	395.8	COG3622	Hydroxypyruvate isomerase	260
2904477719	292	99.65	1	284	1	285	2.4e-112	369.1	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2904477720	484	94.22	1	483	18	490	0.0e+00	560.1	COG1953	Cytosine/uracil/thiamine/allantoin permease	497
2904477721	453	99.3	3	443	2	429	0.0e+00	476.9	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2904477722	428	92.76	2	428	19	441	1.4e-67	222.3	COG2233	Xanthine/uracil permease	451
2904477723	381	99.47	1	378	1	376	0.0e+00	514	COG1929	Glycerate kinase	378
2904477724	263	99.62	1	263	1	263	2.1e-102	336.6	COG3257	Uncharacterized protein, possibly involved in glyoxylate utilization	264
2904477725	408	98.56	5	408	5	416	3.1e-65	215.1	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2904477726	349	98.28	1	344	4	346	7.8e-123	404.1	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
2904477727	555	98.98	18	361	1	291	1.2e-71	234.8	COG0074	Succinyl-CoA synthetase, alpha subunit	293
2904477730	299	99.36	2	297	2	311	1.9e-110	363	COG0549	Carbamate kinase	312
2904477731	81	98.61	1	72	2	72	7.2e-38	122.8	COG3089	Uncharacterized conserved protein YheU, UPF0270 family	72
2904477732	331	95.11	1	326	16	346	3.6e-129	424.8	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
2904477733	200	96.63	1	200	3	203	2.5e-41	135.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2904477734	638	99.07	1	522	3	532	0.0e+00	617.3	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2904477735	184	97.91	5	179	2	188	5.9e-56	183.7	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
2904477736	615	75.34	411	598	28	195	1.2e-33	108.1	COG1226	Voltage-gated potassium channel Kch	212
2904477736	615	97.75	14	406	9	399	9.6e-107	351.3	COG0475	Kef-type K+ transport system, membrane component KefB	397
2904477737	67	95.65	1	67	4	69	1.1e-36	119.2	COG3529	Predicted nucleic-acid-binding protein, contains Zn-ribbon domain	66
2904477738	201	99.44	1	177	1	176	1.1e-63	208.3	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
2904477739	72	98.61	1	72	2	72	1.1e-30	100.3	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
2904477740	284	99.51	50	263	2	206	1.8e-75	247.9	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
2904477741	240	99.09	19	235	2	219	2.0e-94	309.6	COG2964	Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains	220
2904477742	130	99.21	3	130	2	126	4.6e-47	153.5	COG1553	Sulfur relay (sulfurtransferase) complex TusBCD TusD component, DsrE family	126
2904477743	119	100	1	119	1	118	3.8e-48	156.7	COG2923	Sulfur relay (sulfurtransferase) complex TusC component, DsrF/TusC family	118
2904477744	95	100	1	95	1	96	1.3e-31	102.8	COG2168	Sulfur transfer complex TusBCD TusB component, DsrH family	96
2904477745	124	95.35	1	123	7	129	4.0e-63	205.1	COG0048	Ribosomal protein S12	129
2904477746	156	99.32	2	149	2	148	8.9e-64	207.9	COG0049	Ribosomal protein S7	148
2904477747	704	99.31	1	704	1	724	0.0e+00	982.2	COG0480	Translation elongation factor EF-G, a GTPase	697
2904477748	394	99.49	1	394	2	393	0.0e+00	762.1	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2904477749	159	99.36	1	157	1	156	1.4e-72	237	COG2193	Bacterioferritin (cytochrome b1)	157
2904477750	277	94.14	21	276	9	249	2.6e-67	221.4	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
2904477751	152	82.32	1	152	26	174	8.2e-20	65.7	COG3149	Type II secretory pathway, component PulM	181
2904477752	391	97.44	4	390	6	385	2.9e-62	204.9	COG3297	Type II secretory pathway, component PulL	390
2904477753	328	97.53	1	327	1	316	1.7e-61	202.6	COG3156	Type II secretory pathway, component PulK	323
2904477754	227	96.02	1	196	6	198	8.5e-26	85.3	COG4795	Type II secretory pathway, component PulJ	194
2904477755	115	32.05	1	109	10	59	3.0e-06	21.9	COG2165	Type II secretory pathway, pseudopilin PulG	149
2904477756	173	31.41	2	156	6	54	4.2e-11	36.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
2904477757	151	90.38	9	146	5	145	2.4e-33	110.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
2904477758	405	99.75	1	405	1	397	1.2e-118	390.6	COG1459	Type II secretory pathway, component PulF	397
2904477759	508	91.93	7	498	41	507	0.0e+00	608.5	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2904477760	567	81.49	1	537	101	602	0.0e+00	449.9	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
2904477762	555	99.81	33	547	1	535	0.0e+00	698.8	COG4147	Na+(or H+)/acetate symporter ActP	529
2904477763	103	99.02	1	103	1	101	1.3e-43	141.5	COG3162	Uncharacterized membrane protein, DUF485 family	102
2904477764	653	100	68	632	1	552	0.0e+00	816.8	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2904477765	192	98.4	1	192	4	187	5.6e-36	118.6	COG3539	Pilin (type 1 fimbria component protein)	184
2904477766	833	96.18	5	832	16	821	0.0e+00	758.6	COG3188	Outer membrane usher protein FimD/PapC	835
2904477767	245	97.91	1	231	6	239	3.7e-68	223.6	COG3121	P pilus assembly protein, chaperone PapD	235
2904477769	90	47.83	25	82	5	37	3.9e-06	20.7	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2904477771	291	81.08	1	158	11	130	5.7e-20	65.2	COG3710	DNA-binding winged helix-turn-helix (wHTH) domain	148
2904477772	342	96.81	7	339	4	306	6.6e-87	285.6	COG1619	Muramoyltetrapeptide carboxypeptidase LdcA (peptidoglycan recycling)	313
2904477773	438	49.61	226	433	6	195	1.2e-39	29.9	COG0477	MFS family permease	338
2904477773	438	74.67	4	260	5	290	1.2e-39	107.6	COG0477	MFS family permease	338
2904477774	386	99.2	1	376	1	370	1.5e-83	274.9	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2904477776	191	64.59	1	187	15	149	2.6e-08	29.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904477777	578	99.67	1	578	1	609	0.0e+00	719.2	COG4232	Thiol:disulfide interchange protein	569
2904477778	433	99.77	1	433	1	435	0.0e+00	623.9	COG2704	Anaerobic C4-dicarboxylate transporter	436
2904477779	478	99.58	2	473	2	470	0.0e+00	811.9	COG1027	Aspartate ammonia-lyase	471
2904477780	163	96.89	1	159	2	157	3.2e-53	173.8	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
2904477781	97	98.96	1	97	1	95	1.4e-37	122.2	COG0234	Co-chaperonin GroES (HSP10)	96
2904477782	548	98.55	1	538	1	542	0.0e+00	621.5	COG0459	Chaperonin GroEL (HSP60 family)	524
2904477784	342	89.19	2	342	12	341	0.0e+00	452.8	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
2904477785	188	99.24	1	131	1	130	7.1e-50	162.4	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
2904477786	42	95.45	1	42	1	42	1.5e-15	51.1	COG5510	Predicted small secreted protein	44
2904477787	44	100	1	44	1	44	2.8e-20	66.3	COG5510	Predicted small secreted protein	44
2904477788	174	96.57	1	174	5	173	1.3e-67	220.9	COG3040	Bacterial lipocalin	174
2904477789	119	99.15	1	119	1	117	4.1e-57	185.9	COG3080	Fumarate reductase subunit D	118
2904477790	136	98.45	7	135	2	128	1.4e-59	194.1	COG3029	Fumarate reductase subunit C	129
2904477791	244	97.45	5	239	3	231	5.2e-93	304.7	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
2904477792	599	99.29	1	573	5	566	0.0e+00	749.6	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2904477793	325	99.69	1	325	1	321	0.0e+00	516.6	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
2904477794	454	96.05	1	453	6	443	2.1e-126	416.2	COG2233	Xanthine/uracil permease	451
2904477795	452	97.64	3	447	4	417	1.8e-105	347.2	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2904477796	1122	97.65	197	1118	2	833	0.0e+00	953.3	COG3264	Small-conductance mechanosensitive channel	835
2904477797	325	98.84	8	283	2	256	3.9e-87	285.6	COG0688	Phosphatidylserine decarboxylase	239
2904477798	345	98.34	28	342	4	300	2.7e-107	352.6	COG1162	Putative ribosome biogenesis GTPase RsgA	301
2904477799	184	99.46	1	184	1	183	2.5e-94	308.2	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
2904477803	384	100	9	352	1	341	0.0e+00	531.5	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
2904477804	504	96.53	224	501	9	286	9.7e-93	304.3	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
2904477804	504	99.02	14	213	2	204	7.9e-64	209	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
2904477805	155	96.64	4	151	3	146	1.1e-53	175.3	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
2904477806	588	36.73	523	588	81	134	3.5e-24	44.8	COG1388	LysM repeat	124
2904477806	588	38.78	434	534	79	135	3.5e-24	40	COG1388	LysM repeat	124
2904477806	588	94.36	78	427	15	265	3.9e-83	272.8	COG0860	N-acetylmuramoyl-L-alanine amidase	231
2904477807	639	97.98	1	639	1	632	0.0e+00	619.4	COG0323	DNA mismatch repair ATPase MutL	638
2904477808	313	96.1	8	313	3	298	7.1e-122	400.5	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
2904477809	102	97.4	1	76	1	75	1.1e-39	128.1	COG1923	sRNA-binding regulator protein Hfq	77
2904477810	434	98.79	6	423	3	409	0.0e+00	534.9	COG2262	50S ribosomal subunit-associated GTPase HflX	411
2904477811	432	97.01	84	374	6	297	2.1e-76	251.2	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2904477812	332	96.68	1	332	8	298	2.3e-89	294	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2904477813	66	98.39	1	62	1	61	2.4e-30	98.8	COG3242	Uncharacterized conserved protein YjeT, DUF2065 family	62
2904477814	432	99.53	2	431	2	429	0.0e+00	650.2	COG0104	Adenylosuccinate synthase	430
2904477815	125	79.33	1	124	17	135	4.7e-36	118.4	COG1959	DNA-binding transcriptional regulator, IscR family	150
2904477816	832	99.86	15	729	2	711	0.0e+00	892.1	COG0557	Exoribonuclease R	706
2904477817	247	91.25	1	245	22	261	2.6e-88	290.1	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2904477818	543	90.73	39	450	36	397	1.2e-75	249.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2904477820	649	91.53	191	646	37	425	9.1e-96	316.2	COG0840	Methyl-accepting chemotaxis protein	408
2904477821	249	22.4	5	87	32	100	1.2e-16	24	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
2904477821	249	48.05	81	249	160	307	1.2e-16	30.1	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
2904477822	130	99.11	2	112	1	111	7.4e-45	145.8	COG0360	Ribosomal protein S6	112
2904477823	75	84.81	1	68	13	79	1.5e-31	103.2	COG0238	Ribosomal protein S18	75
2904477824	150	99.32	1	150	1	147	2.0e-57	187.8	COG0359	Ribosomal protein L9	148
2904477825	207	71.9	2	207	67	240	3.6e-51	168	COG3061	Cell envelope opacity-associated protein A (function unknown)	242
2904477826	206	98.06	1	206	4	205	7.2e-75	245.8	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
2904477827	221	99.55	1	221	1	220	4.1e-101	331.8	COG2846	Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains	221
2904477828	649	98.11	3	566	11	528	0.0e+00	564.4	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
2904477829	248	92.39	1	247	8	262	1.1e-90	297.9	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
2904477830	185	100	1	184	1	184	7.9e-85	277.6	COG3054	Predicted transcriptional regulator	184
2904477832	449	98.4	1	431	4	434	0.0e+00	434	COG1253	Hemolysin or related protein, contains CBS domains	429
2904477833	212	91.95	39	211	4	163	1.0e-70	231.4	COG0225	Peptide methionine sulfoxide reductase MsrA	174
2904477834	578	97.01	3	578	19	603	0.0e+00	680.4	COG0729	Outer membrane translocation and assembly module TamA	594
2904477835	1271	99.48	1	1271	8	1334	0.0e+00	1217.1	COG2911	Autotransporter translocation and assembly factor TamB	1278
2904477836	99	82.5	1	96	21	119	3.0e-29	96.2	COG2105	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family	120
2904477837	176	100	1	175	1	172	1.9e-72	236.9	COG0221	Inorganic pyrophosphatase	171
2904477839	523	91.76	3	517	36	425	3.3e-103	338.8	COG0840	Methyl-accepting chemotaxis protein	408
2904477840	334	99.39	1	332	1	326	0.0e+00	497.9	COG0158	Fructose-1,6-bisphosphatase	326
2904477841	461	98.26	1	453	8	460	0.0e+00	519	COG0773	UDP-N-acetylmuramate-alanine ligase	459
2904477844	156	98.67	4	152	2	149	1.7e-52	171.8	COG1438	Arginine repressor	150
2904477845	312	99.68	1	312	1	314	5.3e-93	305.9	COG0039	Malate/lactate dehydrogenase	313
2904477846	90	95.12	1	82	3	80	9.7e-37	119.1	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
2904477848	310	96.65	1	310	11	327	1.2e-108	357.3	COG0142	Geranylgeranyl pyrophosphate synthase	322
2904477849	103	99.03	1	103	1	102	1.5e-45	148.3	COG0261	Ribosomal protein L21	103
2904477850	85	95.4	1	85	1	83	3.6e-45	146.2	COG0211	Ribosomal protein L27	87
2904477851	318	98.01	3	308	4	298	4.3e-38	125.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2904477852	390	98.62	1	365	1	358	0.0e+00	511	COG0536	GTPase involved in cell partioning and DNA repair	369
2904477853	363	84.01	3	354	47	377	3.9e-51	169	COG0642	Signal transduction histidine kinase	336
2904477854	220	98.71	1	218	1	229	1.0e-77	254.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904477855	477	100	1	476	1	476	0.0e+00	574.7	COG2027	D-alanyl-D-alanine carboxypeptidase	470
2904477857	158	99.34	6	158	1	151	3.5e-63	206.5	COG0782	Transcription elongation factor, GreA/GreB family	151
2904477858	98	98.97	2	98	1	96	7.4e-38	122.9	COG1534	RNA-binding protein YhbY	97
2904477859	209	98.54	7	209	1	202	1.1e-84	277.6	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
2904477860	647	99.33	6	601	1	597	0.0e+00	935.1	COG0465	ATP-dependent Zn proteases	596
2904477861	270	95.32	2	270	9	273	9.5e-110	360.4	COG0294	Dihydropteroate synthase	274
2904477862	446	97.49	1	446	9	474	0.0e+00	474.4	COG1109	Phosphomannomutase	464
2904477863	111	98.92	1	97	1	92	2.0e-34	111.6	COG1314	Preprotein translocase subunit SecG	86
2904477868	150	97.4	1	150	5	154	3.8e-61	199.7	COG0779	Ribosome maturation factor RimP	153
2904477869	502	94.97	157	374	2	190	7.2e-76	248.6	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
2904477870	897	99.47	394	897	2	559	0.0e+00	577.6	COG0532	Translation initiation factor IF-2, a GTPase	509
2904477871	137	97.48	1	125	3	118	2.0e-41	135	COG0858	Ribosome-binding factor A	118
2904477872	314	98.71	2	311	4	309	1.4e-103	340.8	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
2904477875	89	100	1	89	1	89	4.1e-38	123.7	COG0184	Ribosomal protein S15P/S13E	89
2904477877	707	99.42	1	694	3	692	0.0e+00	1089.2	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
2904477878	294	100	1	294	1	297	0.0e+00	528.5	COG4785	Lipoprotein NlpI, contains TPR repeats	297
2904477879	640	94.62	1	533	26	517	0.0e+00	544.8	COG0513	Superfamily II DNA and RNA helicase	513
2904477880	341	96.5	16	333	6	336	3.1e-69	227.8	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2904477881	324	76.99	1	292	17	287	2.8e-38	125.7	COG1566	Multidrug resistance efflux pump	352
2904477882	390	66.21	132	379	81	274	2.3e-04	14.4	COG0842	ABC-type multidrug transport system, permease component	286
2904477883	387	71.32	162	375	66	254	3.6e-01	3.4	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2904477884	293	72	4	292	2	253	2.9e-64	211.5	COG0826	Collagenase-like protease, PrtC family	347
2904477885	331	87.71	1	331	6	312	1.1e-111	367.5	COG0826	Collagenase-like protease, PrtC family	347
2904477886	157	88.69	1	156	12	160	2.5e-63	207	COG3154	Predicted lipid carrier protein YhbT, SCP2 domain	168
2904477887	167	97.66	1	167	4	170	1.8e-57	188.3	COG3153	Predicted N-acetyltransferase YhbS	171
2904477888	90	81.05	1	85	9	85	3.8e-23	75.6	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
2904477889	144	95.17	6	144	2	139	5.4e-51	166.6	COG3787	Uncharacterized conserved protein YhbP, UPF0306 family	145
2904477890	213	67.39	2	211	4	189	1.6e-30	100.8	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2904477891	212	90.53	7	184	17	188	1.9e-33	109.8	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2904477892	191	92.71	1	185	4	181	1.2e-69	227.8	COG3709	Ribose 1,5-bisphosphokinase PhnN	192
2904477893	378	100	1	378	1	377	0.0e+00	581.4	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
2904477894	235	97.87	1	234	1	230	8.1e-122	399.3	COG4778	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL	235
2904477895	263	98.45	7	263	3	256	0.0e+00	483.9	COG4107	ABC-type phosphonate transport system, ATPase component	258
2904477896	291	97.59	1	290	4	287	0.0e+00	595.2	COG3627	Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase	291
2904477897	360	98.09	1	360	1	360	0.0e+00	638.7	COG3626	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI	367
2904477898	193	98.47	1	192	4	196	1.6e-68	224.5	COG3625	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH	196
2904477899	147	96.69	1	147	5	150	1.5e-62	204.3	COG3624	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG	151
2904477900	241	98.33	3	241	5	239	2.5e-66	217.8	COG2188	DNA-binding transcriptional regulator, GntR family	236
2904477901	114	93.1	1	111	8	115	8.4e-40	129.9	COG4679	Phage-related protein	116
2904477902	95	91.21	1	91	4	86	3.1e-34	111.4	COG5606	Predicted DNA-binding protein, XRE-type HTH domain	91
2904477903	53	40	15	53	49	80	2.1e-08	28.5	COG5302	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid	80
2904477904	154	74.19	2	154	5	165	5.6e-33	109.2	COG0602	Organic radical activating enzyme	212
2904477905	727	99.72	16	722	2	711	0.0e+00	788	COG1328	Anaerobic ribonucleoside-triphosphate reductase	700
2904477906	547	98.45	11	526	2	510	0.0e+00	553.3	COG0366	Glycosidase	505
2904477907	472	94.05	96	470	2	396	7.5e-80	263.1	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
2904477907	472	98.88	6	92	1	88	1.8e-26	85.7	COG1264	Phosphotransferase system IIB components	88
2904477908	318	96.71	7	317	2	324	7.4e-73	239.9	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904477909	900	93.89	25	898	45	951	0.0e+00	749.2	COG0474	Magnesium-transporting ATPase (P-type)	917
2904477910	324	18.75	9	71	198	245	4.9e-74	5.3	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2904477910	324	94.92	59	323	12	254	4.9e-74	243.2	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2904477911	248	79.8	7	226	30	187	2.1e-38	126.4	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2904477912	328	95.44	1	323	3	337	7.3e-68	223.7	COG0673	Predicted dehydrogenase	342
2904477913	168	73.13	1	164	55	220	1.5e-37	123.7	COG1451	Predicted metal-dependent hydrolase	223
2904477914	383	97.68	71	379	7	301	5.4e-96	315.4	COG2813	16S rRNA G1207 methylase RsmC	300
2904477915	678	99.17	7	362	3	362	1.2e-115	380.7	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2904477916	288	89.81	19	280	10	247	3.4e-25	83	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2904477917	672	64.25	162	668	218	643	2.1e-111	367.2	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2904477918	765	99.76	46	464	1	416	3.0e-111	366.4	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2904477920	908	99.44	1	905	6	894	0.0e+00	1193.9	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
2904477921	800	99.2	1	800	6	751	0.0e+00	943.5	COG0058	Glucan phosphorylase	750
2904477922	696	99.62	132	694	1	527	0.0e+00	668.3	COG1640	4-alpha-glucanotransferase	520
2904477923	296	98.25	1	296	6	285	1.7e-105	346.7	COG3833	ABC-type maltose transport system, permease component	282
2904477924	514	95.97	54	514	8	293	3.6e-95	313.2	COG1175	ABC-type sugar transport system, permease component	295
2904477925	399	97.16	1	399	5	415	4.8e-129	425.2	COG2182	Maltose-binding periplasmic protein MalE	420
2904477926	369	99.71	1	356	1	349	0.0e+00	470.6	COG3839	ABC-type sugar transport system, ATPase component	338
2904477927	432	100	1	432	1	430	0.0e+00	617	COG4580	Maltoporin (phage lambda and maltose receptor)	429
2904477929	279	81.82	158	277	18	125	9.3e-24	77.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904477930	145	91.11	12	143	6	128	3.9e-12	40.7	COG4954	Uncharacterized protein	135
2904477931	232	40.95	33	206	111	205	7.6e-14	46.8	COG0671	Membrane-associated phospholipid phosphatase	232
2904477932	161	97.02	2	159	5	167	5.5e-52	170.9	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2904477933	447	99.27	21	447	3	411	0.0e+00	546.8	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
2904477934	756	97.29	17	756	20	700	0.0e+00	893	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
2904477935	447	96	117	433	11	298	7.7e-73	239.2	COG2382	Enterochelin esterase or related enzyme	299
2904477936	265	98.45	7	264	3	256	2.4e-100	329.4	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
2904477937	342	92.2	12	342	27	345	4.5e-128	421.3	COG4779	ABC-type enterobactin transport system, permease component	346
2904477938	333	97.01	2	329	6	330	3.3e-86	283.6	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2904477939	322	95.92	3	320	13	318	0.0e+00	455	COG4592	ABC-type Fe2+-enterobactin transport system, periplasmic component	319
2904477941	380	52.27	1	234	1	138	2.2e-02	5.5	COG1729	Periplasmic TolA-binding protein (function unknown)	262
2904477942	332	90.45	23	331	24	326	3.4e-31	103.2	COG0582	Integrase	309
2904477944	87	8.2	1	66	9	49	3.8e-03	10.4	COG3711	Transcriptional antiterminator	491
2904477950	74	31.67	1	72	82	119	1.5e-12	42.5	COG1734	RNA polymerase-binding transcription factor DksA	120
2904477951	288	98.56	3	271	2	274	4.3e-77	253.4	COG0338	Site-specific DNA-adenine methylase	274
2904477956	343	25.81	2	141	28	154	9.7e-92	112	COG5518	Bacteriophage capsid portal protein	492
2904477956	343	49.39	137	342	191	433	9.7e-92	189.4	COG5518	Bacteriophage capsid portal protein	492
2904477957	588	97.85	8	301	7	279	6.0e-55	180.5	COG5484	Uncharacterized protein YjcR	279
2904477962	67	97.14	1	67	3	70	2.4e-30	98.5	COG5004	P2-like prophage tail protein X	70
2904477963	69	30.3	1	67	27	76	7.2e-04	13.9	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
2904477964	169	94.74	23	169	7	150	3.5e-43	141.1	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
2904477967	152	74.29	6	151	24	127	2.7e-06	21.7	COG5005	Mu-like prophage protein gpG	140
2904477969	213	97.83	13	212	1	180	9.9e-52	168.9	COG4540	Phage P2 baseplate assembly protein gpV	184
2904477970	116	87.93	1	115	4	105	1.4e-39	128.7	COG3628	Phage baseplate assembly protein W	116
2904477971	302	98.69	1	302	5	306	8.5e-126	413.6	COG3948	Phage-related baseplate assembly protein	306
2904477972	175	85.92	1	175	2	178	3.5e-65	214	COG4385	Bacteriophage P2-related tail formation protein	206
2904477975	389	20.94	1	90	3	100	0.0e+00	94.7	COG3497	Phage tail sheath protein FI	394
2904477975	389	65.81	86	387	160	467	0.0e+00	359.5	COG3497	Phage tail sheath protein FI	394
2904477976	169	100	1	169	1	169	1.5e-60	198.1	COG3498	Phage tail tube protein FII	169
2904477979	830	12.7	566	741	673	826	1.8e-28	43.4	COG5283	Phage-related tail protein	1213
2904477979	830	21.52	1	550	55	315	1.8e-28	51.4	COG5283	Phage-related tail protein	1213
2904477980	156	97.96	1	146	1	144	8.5e-55	178.8	COG3499	Phage protein U	147
2904477981	387	98.59	9	381	3	351	1.0e-105	347.9	COG3500	Phage protein D	350
2904477982	50	17.42	6	49	139	169	1.3e-03	13.4	COG1772	Uncharacterized protein	178
2904477984	167	98.82	1	167	1	167	1.2e-45	150.3	COG3663	G:T/U-mismatch repair DNA glycosylase	169
2904477988	612	23.46	95	252	8	87	0.0e+00	4.2	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2904477988	612	26.98	33	149	8	99	0.0e+00	9.7	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2904477988	612	99.71	255	611	2	341	0.0e+00	455.4	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2904477989	582	97.32	4	582	1	580	0.0e+00	652.8	COG0358	DNA primase (bacterial type)	568
2904477990	71	100	1	67	1	67	8.9e-33	106.6	COG0828	Ribosomal protein S21	67
2904477991	337	98.55	1	337	1	339	0.0e+00	452.1	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
2904477992	209	99.51	1	193	2	205	7.1e-70	229.4	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
2904477993	118	96.69	1	117	2	118	1.0e-42	139.5	COG1539	Dihydroneopterin aldolase	121
2904477994	275	98.53	3	275	3	271	1.1e-102	337.5	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
2904477995	411	91.33	1	397	24	402	9.1e-104	342.3	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
2904477996	206	99.62	1	205	1	261	2.2e-53	165.5	COG3103	Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family	205
2904477997	435	99.33	1	433	1	445	0.0e+00	490	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
2904477998	945	94.18	7	945	48	954	0.0e+00	1261	COG1391	Glutamine synthetase adenylyltransferase	963
2904477999	475	99.79	1	475	1	471	0.0e+00	735	COG2870	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase	467
2904478000	416	88.62	1	415	9	444	3.4e-52	171.7	COG0531	Amino acid transporter	466
2904478001	90	85.44	1	90	10	97	2.7e-39	128	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
2904478003	217	98.03	11	214	3	201	6.8e-86	281.3	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
2904478005	263	98.14	1	263	4	267	5.2e-101	332	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
2904478006	386	99.75	1	386	1	396	0.0e+00	585	COG0754	Glutathionylspermidine synthase	387
2904478007	223	98.53	1	223	2	202	5.8e-78	255.8	COG5463	Uncharacterized conserved protein YgiB, involved in bioifilm formation, UPF0441/DUF1190 family	198
2904478008	497	96.96	1	439	12	457	5.2e-104	342.9	COG1538	Outer membrane protein TolC	457
2904478009	210	90.7	42	203	3	158	6.4e-20	66.1	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2904478010	141	95.24	1	141	6	145	5.0e-78	254.5	COG3151	Uncharacterized protein YqiB, DUF1249 family	147
2904478011	276	90.13	15	276	2	357	3.4e-50	165.9	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2904478012	193	97.94	1	193	3	192	3.6e-86	282.5	COG3150	Predicted esterase YcpF, UPF0227 family	191
2904478013	631	99.22	1	631	2	637	0.0e+00	776	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
2904478014	101	92.93	1	101	3	94	1.5e-22	73.9	COG1359	Quinol monooxygenase YgiN	100
2904478015	195	98.95	2	193	2	190	3.1e-56	184.6	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
2904478016	757	92.99	1	755	1	756	0.0e+00	866.3	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
2904478017	245	89.66	2	245	4	237	4.6e-56	184.5	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2904478018	471	99.79	5	470	1	483	6.9e-106	349.8	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904478019	274	97.52	2	273	3	277	7.5e-108	354	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2904478020	346	99.12	8	346	3	340	6.5e-106	348.5	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2904478021	312	91.67	173	300	9	129	4.3e-31	101.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904478022	219	93.27	12	219	14	207	3.1e-58	191	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2904478023	397	98.49	1	395	6	396	2.1e-122	403.1	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2904478024	430	99.47	46	426	2	378	0.0e+00	491.4	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2904478025	170	90.96	1	170	5	165	1.1e-40	133.4	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2904478026	325	98.8	1	325	2	329	2.6e-103	340.2	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2904478027	313	98.15	84	296	1	212	2.6e-64	211.5	COG0811	Biopolymer transport protein ExbB/TolQ	216
2904478028	144	98.56	1	139	1	137	3.5e-48	157.6	COG0848	Biopolymer transport protein ExbD	137
2904478029	523	22.86	2	98	134	224	0.0e+00	13.1	COG2721	Altronate dehydratase	381
2904478029	523	99.75	113	523	2	398	0.0e+00	544.9	COG2721	Altronate dehydratase	381
2904478030	447	91.78	3	447	25	437	3.9e-40	132.3	COG2271	Sugar phosphate permease	448
2904478031	256	99.22	3	256	2	254	4.9e-108	354.6	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
2904478032	294	100	1	285	1	286	1.7e-111	366.4	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2904478033	379	99.74	1	378	1	377	0.0e+00	562.3	COG1929	Glycerate kinase	378
2904478034	435	98.92	26	435	5	371	2.5e-79	261	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
2904478035	916	42.86	685	799	74	133	4.4e-45	6.3	COG4999	Uncharacterized domain of BarA-like signal transduction histidine kinase	140
2904478035	916	82.74	20	523	64	389	1.4e-76	253.1	COG0642	Signal transduction histidine kinase	336
2904478035	916	87.86	525	660	4	126	4.4e-45	141	COG4999	Uncharacterized domain of BarA-like signal transduction histidine kinase	140
2904478035	916	88	799	914	3	112	4.5e-19	59.6	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2904478036	456	99.54	12	440	3	436	4.0e-117	386.1	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
2904478037	745	99.45	9	742	5	724	0.0e+00	922.6	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2904478038	267	51.84	2	267	235	487	2.2e-76	252.2	COG3956	Uncharacterized conserved protein YabN, contains tetrapyrrole methylase and MazG-like pyrophosphatase domain	488
2904478039	545	99.63	3	543	2	534	0.0e+00	855.5	COG0504	CTP synthase (UTP-ammonia lyase)	533
2904478040	434	97.41	1	432	1	414	0.0e+00	665.9	COG0148	Enolase	423
2904478041	279	94.68	6	278	4	270	9.1e-66	216.2	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2904478042	517	87.64	440	517	3	80	1.9e-24	79.2	COG1264	Phosphotransferase system IIB components	88
2904478042	517	95.71	11	444	8	409	0.0e+00	448.9	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
2904478043	232	96.94	1	231	7	228	7.0e-91	297.7	COG3010	Putative N-acetylmannosamine-6-phosphate epimerase	229
2904478044	228	99.08	5	228	2	216	1.6e-65	215.7	COG0602	Organic radical activating enzyme	212
2904478045	119	76.97	1	118	1	117	3.7e-35	115.5	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
2904478046	334	46.65	23	294	34	179	1.8e-08	28	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2904478047	583	99.33	1	583	5	597	0.0e+00	723	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
2904478048	583	98.25	23	578	8	512	0.0e+00	613.7	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2904478049	245	89.55	8	245	10	249	1.3e-62	205.9	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2904478050	345	54.65	2	300	89	329	2.8e-32	106.5	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
2904478051	474	98.58	1	210	2	209	5.1e-72	235.7	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
2904478051	474	99.18	214	457	2	243	4.2e-103	338.2	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2904478052	302	94.78	1	302	15	268	1.2e-93	307.8	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2904478053	475	98.39	22	455	1	427	0.0e+00	691.3	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
2904478054	207	98.98	12	207	1	195	4.7e-90	294.7	COG0529	Adenylylsulfate kinase or related kinase	197
2904478056	106	78.81	1	94	25	117	2.9e-34	111.8	COG2919	Cell division protein FtsB	117
2904478057	239	97.41	7	236	4	229	1.1e-82	271.1	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
2904478058	157	98.11	1	157	1	156	2.2e-73	240	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
2904478059	354	38.73	2	188	15	179	1.4e-99	206.4	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
2904478059	354	40.38	177	352	251	422	1.4e-99	120.8	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
2904478060	254	99.61	1	245	1	255	3.5e-92	302.8	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
2904478061	208	93.84	5	208	6	203	5.0e-83	272.1	COG2518	Protein-L-isoaspartate O-methyltransferase	209
2904478062	340	96.2	85	340	2	305	3.0e-52	172.2	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2904478063	328	88.86	2	325	29	331	1.3e-108	357.8	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2904478064	851	99.65	6	849	4	854	0.0e+00	1103.8	COG0249	DNA mismatch repair ATPase MutS	843
2904478066	367	97.69	1	367	4	342	2.7e-119	392.9	COG2951	Membrane-bound lytic murein transglycosylase B	343
2904478067	164	97.55	1	163	2	160	9.7e-66	214.6	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
2904478068	354	99.31	1	283	2	290	9.7e-127	416.2	COG0468	RecA/RadA recombinase	279
2904478069	229	86.63	31	229	17	165	2.6e-56	183.2	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
2904478070	875	99.43	1	875	5	881	0.0e+00	1220.2	COG0013	Alanyl-tRNA synthetase	879
2904478071	61	82.19	1	61	1	60	3.5e-35	114.5	COG1551	sRNA-binding carbon storage regulator CsrA	73
2904478076	188	84.16	4	187	1	186	3.1e-53	175.2	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2904478077	142	90.68	1	142	15	160	6.1e-46	150.6	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
2904478078	523	99.42	1	518	2	516	0.0e+00	801.2	COG2918	Gamma-glutamylcysteine synthetase	518
2904478080	171	98.14	1	162	1	158	7.8e-76	247.6	COG1854	S-ribosylhomocysteine lyase LuxS, autoinducer biosynthesis	161
2904478081	429	99.53	5	426	2	422	0.0e+00	651.1	COG4536	Mg2+ and Co2+ transporter CorB, contains DUF21, CBS pair, and CorC-HlyC domains	423
2904478082	263	99.25	1	263	2	264	2.5e-109	359.5	COG4137	ABC-type uncharacterized transport system, permease component	265
2904478083	453	98.89	1	452	1	447	0.0e+00	667	COG0541	Signal recognition particle GTPase	451
2904478084	111	86.67	30	111	1	78	2.0e-33	108.6	COG0228	Ribosomal protein S16	87
2904478085	182	96.55	1	182	5	172	2.6e-66	216.9	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
2904478086	257	99.59	1	244	1	243	1.4e-106	349.3	COG0336	tRNA G37 N-methylase TrmD	240
2904478087	115	95.08	1	114	6	121	5.2e-51	166.2	COG0335	Ribosomal protein L19	115
2904478088	59	30.13	2	55	1	47	2.9e-04	14.1	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
2904478089	366	97.74	9	361	3	348	3.2e-84	277.2	COG3500	Phage protein D	350
2904478090	156	98.64	1	147	1	145	1.4e-49	161.9	COG3499	Phage protein U	147
2904478094	169	100	1	169	1	169	2.7e-62	203.8	COG3498	Phage tail tube protein FII	169
2904478095	389	20.94	1	90	3	100	0.0e+00	94.7	COG3497	Phage tail sheath protein FI	394
2904478095	389	66.03	85	387	159	467	0.0e+00	364.9	COG3497	Phage tail sheath protein FI	394
2904478098	175	85.92	1	175	2	178	1.9e-66	218.2	COG4385	Bacteriophage P2-related tail formation protein	206
2904478099	302	98.69	1	302	5	306	0.0e+00	432.7	COG3948	Phage-related baseplate assembly protein	306
2904478100	116	89.66	1	114	1	104	6.1e-42	136.3	COG3628	Phage baseplate assembly protein W	116
2904478101	213	98.91	13	213	1	182	1.1e-55	182	COG4540	Phage P2 baseplate assembly protein gpV	184
2904478103	142	14.79	3	126	56	118	1.2e-04	15.7	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
2904478104	169	95.39	23	169	6	150	2.0e-48	158.3	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
2904478106	67	97.14	1	67	3	70	1.7e-28	92.7	COG5004	P2-like prophage tail protein X	70
2904478109	73	58.33	1	72	49	118	1.9e-11	38.9	COG1734	RNA polymerase-binding transcription factor DksA	120
2904478111	196	62.2	4	75	15	65	3.2e-04	14.4	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
2904478112	358	98.58	2	352	2	347	0.0e+00	542.5	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
2904478113	373	93.07	1	95	7	100	4.8e-29	94.4	COG1605	Chorismate mutase	101
2904478113	373	99.28	97	353	3	279	3.7e-78	256.7	COG0287	Prephenate dehydrogenase	279
2904478114	384	93.07	1	96	7	100	6.3e-26	84.3	COG1605	Chorismate mutase	101
2904478114	384	98.57	101	381	3	278	2.7e-101	332.7	COG0077	Prephenate dehydratase	279
2904478116	114	97.27	1	108	1	107	8.9e-37	120.3	COG1544	Ribosome-associated translation inhibitor RaiA	110
2904478117	244	91.73	2	244	2	234	4.7e-94	308.9	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
2904478118	325	98.97	6	303	4	292	7.1e-94	308.8	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2904478119	218	88.45	1	218	29	250	7.1e-78	255.8	COG1496	Copper oxidase (laccase) domain	249
2904478121	857	99.13	5	857	2	799	0.0e+00	1163.6	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2904478124	116	92.5	1	113	6	116	5.4e-14	46.8	COG4994	Uncharacterized protein	120
2904478125	262	92.75	3	261	3	258	3.6e-61	201.6	COG2162	Arylamine N-acetyltransferase	275
2904478126	462	96.93	1	460	13	454	8.0e-111	365.4	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2904478127	306	96.35	1	298	9	298	2.4e-39	129.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2904478128	280	96.47	1	262	3	275	1.4e-54	179.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904478129	236	93.83	25	236	1	213	3.7e-67	220.2	COG2049	Allophanate hydrolase subunit 1	223
2904478130	333	98.42	7	327	1	311	6.3e-110	361.3	COG1984	Allophanate hydrolase subunit 2	314
2904478131	296	85.58	5	294	1	279	5.0e-58	191.3	COG3547	Transposase	303
2904478133	104	48.98	1	104	74	169	1.5e-30	100.6	COG1045	Serine acetyltransferase	194
2904478134	631	64.05	300	461	87	241	4.2e-26	34.2	COG2202	PAS domain	232
2904478134	631	73.97	24	298	64	242	4.2e-26	50.5	COG2202	PAS domain	232
2904478134	631	95.63	449	630	6	180	1.5e-47	156.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904478135	343	81.82	201	330	21	128	2.3e-16	53.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904478137	557	63.8	88	551	218	640	1.0e-101	335.3	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2904478138	288	94.31	1	286	3	284	1.3e-82	271.2	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2904478139	201	98.6	1	201	1	212	1.0e-48	160.5	COG0625	Glutathione S-transferase	211
2904478140	286	99.29	2	286	1	279	2.5e-105	346.1	COG2240	Pyridoxal/pyridoxine/pyridoxamine kinase	281
2904478141	424	99.5	1	424	2	403	0.0e+00	512.1	COG0162	Tyrosyl-tRNA synthetase	401
2904478142	221	98.6	4	221	4	214	4.4e-91	298.4	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
2904478143	103	78.76	1	103	23	111	1.2e-26	87.1	COG3895	Membrane-bound inhibitor of C-type lysozyme	112
2904478144	372	99.2	1	368	2	372	0.0e+00	519.7	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
2904478146	156	100	1	154	1	154	1.4e-64	211.1	COG3133	Outer membrane lipoprotein SlyB	154
2904478147	103	71.43	2	98	37	131	7.5e-22	72.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
2904478149	285	92.9	1	285	11	337	1.8e-88	290	COG1566	Multidrug resistance efflux pump	352
2904478150	683	96.94	11	674	10	674	3.9e-120	396.5	COG1289	Uncharacterized membrane protein YccC	674
2904478151	298	98.32	2	298	6	298	0.0e+00	455.8	COG4989	Predicted oxidoreductase	298
2904478152	79	98.65	5	78	1	73	5.9e-30	97.7	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
2904478153	382	98.07	18	382	2	357	8.4e-111	365.1	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2904478154	135	100	1	125	1	146	3.1e-25	84.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2904478155	227	95.28	8	224	3	244	7.9e-24	78.4	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2904478156	119	96.19	2	105	4	104	1.6e-48	157.2	COG0278	Glutaredoxin-related protein	105
2904478158	299	87.55	9	290	32	249	2.4e-52	172.7	COG0791	Cell wall-associated hydrolase, NlpC family	197
2904478161	341	99.1	2	335	1	331	1.9e-120	396.6	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904478162	301	96.01	5	297	5	293	2.0e-57	189.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904478163	403	47	196	387	11	190	9.8e-28	11.3	COG0477	MFS family permease	338
2904478163	403	54.83	2	214	5	214	9.8e-28	84.9	COG0477	MFS family permease	338
2904478164	383	98.6	97	372	4	285	1.1e-113	373.4	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2904478165	217	96.59	1	211	1	198	9.6e-78	254.3	COG0307	Riboflavin synthase alpha chain	204
2904478166	457	95.65	2	455	15	454	5.0e-123	405.2	COG0534	Na+-driven multidrug efflux pump	455
2904478170	470	99.37	1	470	4	478	0.0e+00	635.9	COG0469	Pyruvate kinase	477
2904478171	78	100	1	78	1	79	9.1e-41	132.7	COG4238	Outer membrane murein-binding lipoprotein Lpp	78
2904478173	337	97.52	1	239	7	242	5.6e-59	194.6	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2904478174	137	91.67	1	137	10	141	1.4e-54	178.1	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
2904478175	406	99.27	1	405	1	406	0.0e+00	529.2	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
2904478176	433	70.28	100	426	115	419	3.3e-61	201.7	COG0719	Fe-S cluster assembly scaffold protein SufB	412
2904478177	248	97.22	1	248	3	247	5.5e-109	357.6	COG0396	Fe-S cluster assembly ATPase SufC	251
2904478178	507	99.77	43	505	1	433	0.0e+00	520.8	COG0719	Fe-S cluster assembly scaffold protein SufB	412
2904478179	123	98.18	15	123	3	110	1.0e-37	122.9	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2904478181	139	96.45	3	139	3	138	3.0e-37	121.8	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2904478182	1018	97.87	16	543	10	468	6.7e-112	368.8	COG0277	FAD/FMN-containing dehydrogenase	459
2904478182	1018	98.75	568	1018	3	398	1.1e-79	262.5	COG0247	Fe-S oxidoreductase	388
2904478184	365	96.11	1	360	11	356	1.1e-69	229.5	COG0628	Predicted PurR-regulated permease PerM	355
2904478186	791	98.98	9	791	5	783	0.0e+00	941.7	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
2904478187	269	97.8	1	269	6	272	3.7e-101	332.6	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
2904478188	348	98.86	1	348	3	349	0.0e+00	539.4	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
2904478189	345	97.71	1	345	9	349	0.0e+00	508.8	COG3720	Putative heme degradation protein	349
2904478190	276	92	1	276	22	297	6.7e-92	301.9	COG4558	ABC-type hemin transport system, periplasmic component	300
2904478191	342	97.31	10	337	5	330	1.3e-99	327.6	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2904478192	262	98.84	7	262	3	258	4.1e-110	361.3	COG4559	ABC-type hemin transport system, ATPase component	259
2904478193	484	98.39	1	484	9	497	0.0e+00	642.7	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
2904478194	242	88.72	7	241	19	246	1.4e-17	57.7	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2904478196	337	95.62	3	247	12	251	1.1e-73	241.8	COG0095	Lipoate-protein ligase A	248
2904478197	159	50.6	28	157	124	249	8.0e-43	141.7	COG0791	Cell wall-associated hydrolase, NlpC family	197
2904478198	129	37.87	1	129	183	296	4.7e-12	40.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2904478199	110	24.58	1	109	69	142	3.0e-11	37.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2904478200	556	97.44	1	528	12	544	8.8e-108	355.9	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
2904478201	299	89.55	1	293	19	258	6.1e-23	75.1	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2904478202	660	93.83	1	294	2	290	2.7e-96	316.6	COG0223	Methionyl-tRNA formyltransferase	307
2904478202	660	97.82	312	653	3	316	1.0e-62	206.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2904478203	326	93.31	7	315	4	338	1.3e-40	134.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2904478204	380	98.93	1	380	3	373	0.0e+00	463.8	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2904478206	253	98.39	3	253	3	246	1.9e-100	329.8	COG4138	ABC-type cobalamin transport system, ATPase component	248
2904478207	183	98.77	1	183	2	161	1.1e-68	223.1	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
2904478208	335	98.47	6	333	5	325	0.0e+00	508.8	COG4139	ABC-type cobalamin transport system, permease component	326
2904478210	52	6.29	8	51	72	92	9.1e-02	5.3	COG4371	Uncharacterized membrane protein	334
2904478211	98	96.81	2	95	2	92	2.6e-37	121.4	COG0776	Bacterial nucleoid DNA-binding protein	94
2904478212	795	100	143	794	1	652	0.0e+00	786.3	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
2904478213	327	98.81	1	325	5	337	0.0e+00	438.1	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
2904478215	118	99.15	1	118	1	117	3.4e-58	189.4	COG0292	Ribosomal protein L20	118
2904478216	65	100	1	65	1	65	1.9e-31	102.8	COG0291	Ribosomal protein L35	65
2904478217	116	63.07	1	116	65	175	1.6e-48	159	COG0290	Translation initiation factor IF-3	176
2904478218	642	99.66	34	641	2	593	0.0e+00	905.6	COG0441	Threonyl-tRNA synthetase	589
2904478219	226	98.05	5	222	4	204	4.1e-65	213.3	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
2904478220	211	54.46	9	207	137	301	2.6e-38	126.8	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2904478221	289	99.65	1	286	1	285	0.0e+00	441.6	COG3001	Fructosamine-3-kinase	286
2904478223	221	95.93	6	219	2	213	5.2e-52	171.2	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2904478224	278	100	1	278	1	278	0.0e+00	491.3	COG3717	5-keto 4-deoxyuronate isomerase	278
2904478225	253	98.88	6	252	3	267	3.1e-69	227.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904478226	185	79.7	1	183	1	157	1.2e-40	133.8	COG1988	Membrane-bound metal-dependent hydrolase YbcI, DUF457 family	190
2904478227	463	99.56	1	458	2	457	0.0e+00	745.4	COG1823	L-cystine uptake protein TcyP, sodium:dicarboxylate symporter family	458
2904478228	114	33.13	5	114	1	108	1.3e-20	68.5	COG3547	Transposase	303
2904478229	401	99.49	6	400	2	395	5.2e-123	405.3	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2904478230	307	98.01	1	298	2	296	1.7e-58	193.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904478231	146	53.74	11	141	67	145	1.4e-10	36.4	COG0511	Biotin carboxyl carrier protein	140
2904478232	260	98.81	1	252	1	249	4.4e-96	315.4	COG1540	Lactam utilization protein B (function unknown)	252
2904478233	249	97.97	1	237	4	244	5.5e-75	246.6	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2904478234	231	92.98	1	229	15	226	4.1e-66	217.3	COG0765	ABC-type amino acid transport system, permease component	222
2904478235	249	94.74	3	229	12	227	4.8e-70	230	COG0765	ABC-type amino acid transport system, permease component	222
2904478236	245	98.76	3	243	2	240	2.9e-113	371.3	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2904478237	117	87.39	1	117	1	104	2.5e-31	102.7	COG2315	Predicted DNA-binding protein with ?double-wing? structural motif, MmcQ/YjbR family	118
2904478239	289	89.13	1	283	1	246	1.8e-41	136.7	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2904478241	291	98.01	1	286	1	295	1.2e-58	193.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904478242	437	97.42	30	418	3	380	1.9e-42	140.3	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2904478243	218	97.3	1	217	7	222	4.0e-89	292.2	COG2011	ABC-type methionine transport system, permease component	222
2904478244	384	99.12	44	379	2	338	1.1e-126	417	COG1135	ABC-type methionine transport system, ATPase component	339
2904478245	280	97.04	14	280	9	270	1.6e-95	313.5	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
2904478246	768	97.42	26	753	3	643	4.8e-38	125.6	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
2904478247	238	99.16	3	237	2	236	4.4e-102	334.6	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2904478248	297	99.21	6	289	3	254	3.6e-110	361.4	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2904478249	429	96.28	95	422	8	318	8.2e-98	322.1	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2904478250	304	98.67	1	303	3	299	4.2e-97	319.7	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2904478251	374	96.45	18	374	4	356	2.1e-95	314.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2904478252	71	20.78	1	52	1	32	3.4e-04	15	COG3133	Outer membrane lipoprotein SlyB	154
2904478253	609	89.41	230	608	44	423	1.4e-105	348.6	COG0840	Methyl-accepting chemotaxis protein	408
2904478254	324	97.88	1	323	3	325	0.0e+00	452.5	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
2904478255	699	95.36	19	698	3	680	0.0e+00	674.2	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2904478256	428	78.98	11	362	19	296	7.8e-30	93.7	COG1566	Multidrug resistance efflux pump	352
2904478258	355	99.14	4	353	3	349	0.0e+00	493.2	COG3768	Uncharacterized membrane protein YcjF, UPF0283 family	350
2904478259	465	99.78	1	465	2	460	0.0e+00	763.9	COG3106	Predicted ATPase, YcjX-like family	467
2904478261	119	92.75	6	74	2	65	4.1e-22	72	COG1983	Phage shock protein PspC (stress-responsive transcriptional regulator)	70
2904478262	75	28.37	1	67	29	87	3.4e-04	14.7	COG3166	Tfp pilus assembly protein PilN	206
2904478263	223	98.67	1	222	1	223	1.4e-65	215.4	COG1842	Phage shock protein A	225
2904478264	335	77.47	1	331	95	431	2.0e-123	407	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain	403
2904478266	396	99.69	5	375	1	325	3.1e-106	349.8	COG0523	GTPase, G3E family	323
2904478267	560	95.82	1	550	12	561	5.8e-112	369.5	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2904478268	321	100	1	321	1	321	0.0e+00	547.2	COG4168	ABC-type antimicrobial peptide transport system, permease component	321
2904478269	296	100	1	296	1	296	0.0e+00	502.6	COG4171	ABC-type antimicrobial peptide transport system, permease component	296
2904478270	330	100	1	330	1	330	0.0e+00	678.6	COG4170	ABC-type antimicrobial peptide transport system, ATPase component	330
2904478271	269	99.25	2	268	2	266	0.0e+00	502.7	COG4167	ABC-type antimicrobial peptide transport system, ATPase component	267
2904478272	400	24.35	305	390	105	151	1.3e-55	7.8	COG4950	N-terminal domain of uncharacterized protein YciW (function unknown)	193
2904478272	400	96.89	15	202	3	189	1.3e-55	175.4	COG4950	N-terminal domain of uncharacterized protein YciW (function unknown)	193
2904478273	503	98.6	2	491	5	496	0.0e+00	572.3	COG3104	Dipeptide/tripeptide permease	498
2904478274	334	99.08	5	325	1	323	2.9e-59	195.3	COG3547	Transposase	303
2904478275	263	99.59	14	258	1	245	3.3e-88	289.1	COG1414	DNA-binding transcriptional regulator, IclR family	246
2904478276	465	49.09	264	460	8	195	2.3e-40	31.5	COG0477	MFS family permease	338
2904478276	465	78.07	13	295	4	302	2.3e-40	104.4	COG0477	MFS family permease	338
2904478277	293	95.83	1	293	8	306	1.8e-85	281.4	COG0501	Zn-dependent protease with chaperone function	302
2904478278	690	99.02	129	600	2	405	0.0e+00	447.6	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
2904478279	229	100	1	229	1	211	3.0e-105	344.6	COG3109	sRNA-binding protein	208
2904478280	165	92.64	1	154	11	161	1.9e-66	217.1	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
2904478281	415	97.85	1	415	9	417	0.0e+00	560.8	COG2995	Uncharacterized paraquat-inducible protein A	418
2904478282	876	11.57	554	630	204	267	0.0e+00	40.4	COG3008	Paraquat-inducible protein B	553
2904478282	876	41.77	625	864	43	273	0.0e+00	160.6	COG3008	Paraquat-inducible protein B	553
2904478282	876	99.82	1	568	1	552	0.0e+00	676.8	COG3008	Paraquat-inducible protein B	553
2904478283	489	86.03	1	318	50	357	4.9e-93	306.7	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
2904478283	489	92.31	349	478	11	130	1.7e-41	135	COG3270	Ribosome biogenesis protein, NOL1/NOP2/fmu family	127
2904478284	573	28.93	130	242	118	187	4.3e-44	22.3	COG2202	PAS domain	232
2904478284	573	53.72	2	137	111	240	4.3e-44	54.9	COG2202	PAS domain	232
2904478284	573	59.09	222	383	100	242	4.3e-44	64.9	COG2202	PAS domain	232
2904478284	573	94.54	378	564	9	181	1.6e-49	161.7	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904478287	130	94.29	1	129	9	140	2.5e-44	145.1	COG4405	Uncharacterized protein YhfF	140
2904478290	392	96.95	7	392	10	390	0.0e+00	444.7	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2904478291	232	67	19	232	92	292	1.1e-57	190.7	COG3921	Uncharacterized conserved protein	300
2904478292	208	18.77	1	63	4	67	2.7e-56	55.7	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2904478292	208	43.11	61	207	194	340	2.7e-56	134.8	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2904478293	551	91.76	39	517	36	425	6.8e-110	362.5	COG0840	Methyl-accepting chemotaxis protein	408
2904478294	659	97.1	3	659	19	654	0.0e+00	927	COG2015	Alkyl sulfatase BDS1 and related hydrolases, metallo-beta-lactamase superfamily	655
2904478296	303	93.44	1	301	11	295	3.1e-85	280.4	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2904478300	294	98.62	5	294	2	286	4.2e-69	227.6	COG1276	Putative copper export protein	289
2904478301	127	96.06	3	127	4	125	2.0e-39	129.3	COG2372	Copper-binding protein CopC (methionine-rich)	127
2904478302	168	98.2	1	167	2	165	1.2e-70	231	COG1528	Ferritin	167
2904478304	318	93.9	16	317	4	280	8.7e-44	144.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904478306	679	99.41	1	679	3	681	0.0e+00	976.9	COG1770	Protease II	682
2904478308	460	71.54	1	399	29	400	0.0e+00	452.9	COG0513	Superfamily II DNA and RNA helicase	513
2904478309	392	99.49	1	392	2	393	0.0e+00	662.4	COG0027	Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	394
2904478310	60	98.33	1	59	1	59	1.4e-26	86.5	COG3140	Uncharacterized conserved protein YoaH, UPF0181 family	60
2904478311	458	95.93	6	457	13	460	0.0e+00	492.8	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2904478312	200	85.47	32	182	11	157	1.8e-17	58	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2904478313	454	29.09	2	94	47	126	0.0e+00	22	COG1760	L-serine deaminase	262
2904478313	454	100	169	450	1	275	0.0e+00	420.5	COG1760	L-serine deaminase	262
2904478314	530	94.9	11	521	22	523	1.0e-84	278.6	COG4943	Environmental sensor c-di-GMP phosphodiesterase, contains periplasmic CSS-motif sensor and cytoplasmic EAL domain	524
2904478315	515	98.63	72	511	3	434	2.7e-108	356.6	COG1253	Hemolysin or related protein, contains CBS domains	429
2904478316	320	95.1	2	142	2	137	6.6e-48	155.8	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
2904478316	320	100	160	318	1	159	7.0e-67	218.6	COG3444	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB	159
2904478317	265	99.62	2	264	1	264	2.8e-102	335.8	COG3715	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC	265
2904478318	280	98.89	4	278	4	271	6.6e-127	416.6	COG3716	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID	269
2904478319	152	100	1	152	1	152	1.4e-64	211.3	COG4811	Uncharacterized membrane protein YobD, UPF0266 family	152
2904478320	190	98.42	1	188	2	188	1.2e-67	221.6	COG1971	Putative Mn2+ efflux pump MntP	190
2904478321	273	63.8	20	269	42	219	1.2e-15	52.6	COG0500	SAM-dependent methyltransferase	257
2904478322	233	80.08	8	232	45	245	3.4e-56	184.6	COG1496	Copper oxidase (laccase) domain	249
2904478324	69	98.51	3	69	2	67	5.7e-37	120.1	COG1278	Cold shock protein, CspA family	67
2904478325	329	91.32	64	328	3	244	1.5e-66	218.7	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
2904478334	523	96.69	1	522	19	573	0.0e+00	519.3	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2904478337	69	34.29	14	69	14	49	1.7e-03	13	COG5548	Uncharacterized membrane protein, UPF0136 family	105
2904478339	417	99.75	8	417	1	407	0.0e+00	643.7	COG0538	Isocitrate dehydrogenase	407
2904478340	178	67.89	1	177	65	231	5.9e-66	216.4	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2904478341	148	76.74	1	131	13	144	5.2e-19	63.2	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2904478342	369	99.16	4	365	2	355	0.0e+00	525.7	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
2904478343	208	99.52	2	208	1	206	3.6e-98	321.7	COG2915	Regulator of phage lambda lysogenization HflD, binds to CII and stimulates its degradation	207
2904478344	456	99.32	12	456	1	436	0.0e+00	487.5	COG0015	Adenylosuccinate lyase	438
2904478345	224	98.71	1	224	1	229	7.2e-78	255.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904478346	485	83.25	120	485	63	390	5.8e-42	138.9	COG0642	Signal transduction histidine kinase	336
2904478347	373	97.92	1	373	9	385	0.0e+00	508.1	COG2850	Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain	383
2904478350	542	97.24	1	541	15	543	0.0e+00	714.4	COG2985	Uncharacterized membrane protein YbjL, putative transporter	544
2904478352	88	96.25	1	85	3	79	1.2e-22	74.4	COG0695	Glutaredoxin	80
2904478353	240	97.69	1	181	6	216	1.1e-33	111	COG0778	Nitroreductase	207
2904478354	300	99.05	1	292	1	312	5.4e-87	285.4	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2904478356	369	96.56	1	369	13	377	5.4e-117	385.4	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2904478357	377	98.58	16	377	4	351	0.0e+00	442.8	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2904478358	317	97.22	20	317	4	283	9.4e-114	374	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2904478359	281	98.13	1	273	5	266	1.2e-95	314.1	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2904478361	376	84.86	1	369	67	436	1.3e-104	345	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
2904478362	247	93.41	1	245	15	255	6.0e-84	275.9	COG1684	Flagellar biosynthesis protein FliR	258
2904478363	89	98.88	1	89	1	88	4.1e-38	123.9	COG1987	Flagellar biosynthesis protein FliQ	89
2904478364	260	95.98	11	259	10	248	3.3e-104	342	COG1338	Flagellar biosynthetic protein FliP	248
2904478365	145	88.57	14	145	13	136	3.9e-34	111.9	COG3190	Flagellar biogenesis protein FliO	137
2904478366	138	80.85	1	126	28	141	1.7e-39	130.2	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
2904478367	340	99.4	1	339	2	332	7.1e-126	414.1	COG1868	Flagellar motor switch protein FliM	332
2904478368	166	93.08	3	166	11	158	2.8e-40	131.9	COG1580	Flagellar basal body-associated protein FliL	159
2904478369	462	95.43	13	462	21	438	2.1e-36	118.5	COG3144	Flagellar hook-length control protein FliK	417
2904478370	148	98.65	1	147	1	146	6.0e-43	140.7	COG2882	Flagellar biosynthesis chaperone FliJ	148
2904478371	454	99.1	4	454	3	440	0.0e+00	647.8	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
2904478372	261	93.83	25	261	8	235	1.8e-61	202	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
2904478373	330	96.76	1	330	12	340	1.3e-126	416.9	COG1536	Flagellar motor switch protein FliG	339
2904478374	569	97.45	9	567	14	547	0.0e+00	658.5	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
2904478375	104	98.11	1	104	3	106	3.9e-31	102.1	COG1677	Flagellar hook-basal body complex protein FliE	105
2904478377	289	95.75	1	289	13	305	3.7e-101	332.7	COG3781	Predicted membrane chloride channel, bestrophin family	306
2904478379	154	70.37	4	131	38	151	4.9e-14	47.1	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904478384	173	66.22	92	172	17	65	4.3e-04	14.2	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
2904478386	52	92.86	1	52	4	55	2.4e-23	76.2	COG0401	Uncharacterized membrane protein YqaE, homolog of Blt101, UPF0057 family	56
2904478388	215	81.82	75	205	17	124	3.5e-17	56.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904478390	145	96.21	1	139	1	127	1.0e-41	136.3	COG1516	Flagellin-specific chaperone FliS	132
2904478391	478	99.2	2	475	4	497	1.5e-115	381.4	COG1345	Flagellar capping protein FliD	483
2904478392	426	100	3	426	1	388	3.4e-114	376.5	COG1344	Flagellin and related hook-associated protein FlgL	360
2904478393	240	92.46	2	239	19	251	3.1e-86	283.4	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
2904478395	336	99.07	10	336	3	322	1.5e-127	419.5	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
2904478396	266	94.35	3	266	8	274	7.7e-75	246.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904478397	222	93.42	2	218	15	227	3.3e-88	289.4	COG0765	ABC-type amino acid transport system, permease component	222
2904478398	250	99.17	2	248	2	241	8.9e-110	359.9	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2904478399	1324	99.5	104	526	3	403	0.0e+00	584.2	COG0506	Proline dehydrogenase	391
2904478399	1324	99.74	529	1324	3	773	0.0e+00	1227.1	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
2904478400	494	99.4	3	488	1	497	0.0e+00	537.7	COG0591	Na+/proline symporter	493
2904478401	283	79.22	1	274	7	330	1.1e-76	252.5	COG0672	High-affinity Fe2+/Pb2+ permease	383
2904478402	375	98.66	1	373	6	373	0.0e+00	567.8	COG2822	Iron uptake system EfeUOB, periplasmic (or lipoprotein) component EfeO/EfeM	376
2904478403	431	97.27	47	431	9	364	4.8e-121	398.5	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
2904478404	382	76.69	30	375	60	263	2.1e-70	231.5	COG0860	N-acetylmuramoyl-L-alanine amidase	231
2904478406	262	72.65	1	262	80	326	6.5e-109	358.5	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
2904478407	366	98.38	7	366	5	368	2.1e-105	346.7	COG0387	Ca2+/H+ antiporter	368
2904478408	77	98.68	1	76	1	75	3.0e-39	127.6	COG4572	Cation transport regulator ChaB	76
2904478409	229	92.11	37	220	8	182	5.6e-69	225.7	COG3703	Cation transport regulator ChaC	190
2904478410	522	95.85	1	522	18	571	7.3e-73	240.7	COG0747	ABC-type transport system, periplasmic component	556
2904478411	350	96.54	18	350	9	315	3.8e-94	309.9	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904478412	292	91.28	2	292	24	295	9.9e-96	314.5	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904478413	294	83.69	16	293	6	277	3.3e-87	286.7	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2904478414	225	86.27	4	225	5	224	4.9e-81	266.1	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
2904478415	525	96.54	1	525	14	571	6.7e-68	224.3	COG0747	ABC-type transport system, periplasmic component	556
2904478416	105	88.46	2	104	3	94	2.6e-36	117.8	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
2904478417	104	96.81	4	99	3	93	5.1e-29	94.8	COG3549	Plasmid maintenance system killer protein	94
2904478419	567	91.91	7	441	18	426	1.2e-80	265.4	COG0038	H+/Cl- antiporter ClcA	443
2904478420	339	92.68	15	337	23	326	9.5e-48	156.8	COG0598	Mg2+ and Co2+ transporter CorA	322
2904478421	1254	100	1	1235	1	1242	0.0e+00	2237.8	COG5013	Nitrate reductase alpha subunit	1227
2904478422	511	99.61	1	511	1	511	0.0e+00	963.4	COG1140	Nitrate reductase beta subunit	513
2904478423	240	95.56	1	180	5	176	2.1e-59	194.4	COG2180	Nitrate reductase assembly protein NarJ, required for insertion of molybdenum cofactor	179
2904478424	226	98.68	4	226	1	225	4.8e-91	298.9	COG2181	Nitrate reductase gamma subunit	228
2904478425	79	32.26	5	75	125	184	1.2e-06	22.3	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
2904478426	287	97.19	2	284	3	279	7.3e-70	230.2	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2904478429	570	99.16	1	570	4	590	0.0e+00	586.6	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2904478431	359	100	2	359	1	360	1.0e-111	367.8	COG3203	Outer membrane protein (porin)	354
2904478432	336	81.71	46	336	61	337	9.2e-84	275.3	COG3367	Uncharacterized conserved protein, NAD-dependent epimerase/dehydratase family	339
2904478433	321	91.96	1	321	5	347	3.6e-56	184.8	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2904478434	622	99.28	1	582	4	551	0.0e+00	719.5	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2904478435	514	93.94	1	512	17	559	5.5e-108	356.6	COG0747	ABC-type transport system, periplasmic component	556
2904478436	306	99.37	1	306	1	316	5.7e-110	361.9	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904478437	303	92.95	13	303	20	296	2.7e-100	329.4	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904478438	359	96.84	24	353	8	344	7.4e-91	299	COG3191	L-aminopeptidase/D-esterase	348
2904478439	273	98.18	1	273	1	269	1.2e-76	251.8	COG2362	D-aminopeptidase	274
2904478440	299	98.34	1	293	1	296	7.4e-56	184.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904478441	362	98.88	3	359	3	355	7.3e-56	183.6	COG0371	Glycerol dehydrogenase or related enzyme, iron-containing ADH family	360
2904478442	284	98.23	2	284	4	280	8.6e-70	229.3	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2904478443	440	48.04	242	437	6	189	1.6e-43	39.1	COG0477	MFS family permease	338
2904478443	440	76.5	16	288	2	294	1.6e-43	108	COG0477	MFS family permease	338
2904478445	254	78.88	2	239	52	249	2.8e-32	106.7	COG4114	Ferric iron reductase protein FhuF, involved in iron transport	251
2904478446	304	97.66	2	302	4	295	5.6e-87	285.5	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2904478447	535	96.88	6	535	17	544	0.0e+00	548.1	COG0405	Gamma-glutamyltranspeptidase	539
2904478448	291	93.96	6	291	16	295	7.8e-103	337.7	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904478449	314	99.37	1	314	1	316	1.0e-120	397.3	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904478450	505	92.56	3	496	27	561	1.5e-112	371.5	COG0747	ABC-type transport system, periplasmic component	556
2904478451	371	97.19	5	317	3	313	2.7e-115	379.3	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2904478452	340	99.38	11	326	1	323	3.5e-129	424.7	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2904478453	244	94.19	6	240	7	233	1.1e-49	163.2	COG2186	DNA-binding transcriptional regulator, FadR family	241
2904478454	694	63.8	161	692	220	642	5.5e-128	422	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2904478455	342	98.8	2	335	2	331	2.8e-105	346.6	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904478456	490	88.76	6	92	4	82	4.6e-28	90.4	COG1264	Phosphotransferase system IIB components	88
2904478456	490	95.48	105	485	12	412	2.7e-66	218.3	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
2904478457	476	98.49	3	475	3	458	0.0e+00	613	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2904478459	304	97.76	5	296	5	310	3.8e-27	86.2	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2904478462	88	9.86	4	31	10	23	4.0e-08	8.9	COG0727	Fe-S-cluster containining protein	132
2904478462	88	22.54	19	87	63	94	4.0e-08	24.9	COG0727	Fe-S-cluster containining protein	132
2904478464	420	98.51	11	361	3	332	7.0e-74	243.2	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2904478465	302	94.96	43	302	6	250	3.6e-68	223.9	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2904478466	265	98.41	5	264	2	248	1.4e-94	310.5	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2904478467	1391	51.44	1	413	1	412	0.0e+00	399.9	COG1251	NAD(P)H-nitrite reductase, large subunit	793
2904478467	1391	96.26	1267	1377	3	105	1.1e-14	47.5	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2904478467	1391	99.63	418	1226	1	798	0.0e+00	1029.6	COG1251	NAD(P)H-nitrite reductase, large subunit	793
2904478468	890	87.3	830	889	3	57	5.0e-12	39	COG2906	Bacterioferritin-associated ferredoxin	63
2904478468	890	94.32	1	700	43	806	0.0e+00	569.2	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2904478469	295	96.72	27	275	2	237	2.3e-96	316.3	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2904478470	280	96.47	10	274	7	279	2.5e-62	205	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904478471	276	99.17	24	265	2	241	1.1e-106	349.7	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2904478472	257	88.16	5	242	18	218	3.5e-52	171.3	COG0765	ABC-type amino acid transport system, permease component	222
2904478473	230	85.53	12	227	24	218	2.9e-44	145.5	COG0765	ABC-type amino acid transport system, permease component	222
2904478474	548	98.91	1	536	5	550	0.0e+00	591.4	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2904478475	279	89.6	2	278	25	291	7.1e-85	278.7	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904478476	331	97.8	18	323	5	315	9.0e-89	292.1	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904478477	540	96.54	1	536	6	563	1.8e-82	272.4	COG0747	ABC-type transport system, periplasmic component	556
2904478478	445	97.38	15	415	10	343	1.7e-87	287.9	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2904478479	186	75.31	9	149	34	155	7.7e-06	20.8	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904478480	177	85.19	4	150	18	155	3.6e-07	25.1	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904478482	73	56.1	20	73	5	50	1.8e-21	70.1	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
2904478484	241	88.93	1	239	1	249	4.9e-62	204.2	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2904478485	30	9.63	1	30	1	29	3.1e-09	30.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904478486	263	87.04	1	260	36	297	6.2e-61	201	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904478487	255	15.72	16	101	15	61	2.4e-19	12.3	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
2904478487	255	40.8	65	254	130	251	2.4e-19	51.5	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
2904478488	282	74.24	155	279	28	125	7.5e-26	84.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904478489	349	93.95	1	343	16	310	7.1e-106	348.3	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
2904478490	216	90.58	3	216	19	220	6.6e-49	160.5	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
2904478491	235	89.24	6	224	20	218	3.4e-51	167.9	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
2904478492	294	97.67	1	290	7	299	4.2e-65	214.1	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
2904478493	514	99.4	3	498	2	496	0.0e+00	527.2	COG2986	Histidine ammonia-lyase	498
2904478494	400	98.75	1	400	6	401	0.0e+00	450	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2904478495	297	86.93	1	294	2	287	3.1e-79	257.2	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2904478496	256	98.11	1	253	6	265	1.4e-72	238.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2904478497	249	96.23	12	247	6	235	1.4e-62	205.5	COG2188	DNA-binding transcriptional regulator, GntR family	236
2904478498	352	98.53	1	345	5	340	5.6e-124	407.8	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2904478499	308	96.68	5	301	5	295	7.3e-36	118.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2904478500	195	85.65	1	193	12	190	1.1e-20	69.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904478501	143	95.97	1	143	7	149	7.6e-17	56.3	COG1981	Uncharacterized membrane protein	149
2904478504	179	98.76	12	173	1	159	7.6e-66	214.8	COG3265	Gluconate kinase	161
2904478505	445	99.33	3	445	2	447	0.0e+00	437.4	COG2610	H+/gluconate symporter or related permease	442
2904478506	604	98.62	3	604	5	574	0.0e+00	680.6	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2904478507	212	98.58	3	212	2	209	1.3e-82	270.5	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
2904478508	386	46.34	36	357	80	313	9.0e-23	74.9	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2904478509	189	83.17	1	189	28	200	1.3e-26	87.6	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2904478510	225	27.02	1	158	2	98	1.3e-22	74.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2904478511	542	78	2	290	8	326	1.3e-28	90.4	COG0672	High-affinity Fe2+/Pb2+ permease	383
2904478512	407	94.91	14	401	16	369	4.1e-63	207.8	COG2822	Iron uptake system EfeUOB, periplasmic (or lipoprotein) component EfeO/EfeM	376
2904478513	423	92.9	41	423	21	360	2.0e-77	255	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
2904478514	150	28.04	23	146	119	171	2.4e-11	37.9	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2904478516	91	29.86	1	87	192	274	5.5e-02	6.1	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
2904478518	188	95.63	1	188	5	179	3.8e-70	229.3	COG0241	Histidinol phosphatase or a related phosphatase	181
2904478519	343	99.71	1	342	1	339	0.0e+00	488.1	COG1135	ABC-type methionine transport system, ATPase component	339
2904478520	217	97.75	1	217	6	222	8.6e-96	314	COG2011	ABC-type methionine transport system, permease component	222
2904478521	271	98.52	1	271	5	270	2.9e-113	371.7	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
2904478523	235	94.87	1	173	4	151	4.6e-59	192.7	COG1720	tRNA (Thr-GGU) A37 N-methylase	156
2904478524	572	99.62	1	568	1	525	0.0e+00	742	COG0442	Prolyl-tRNA synthetase	500
2904478525	225	98.31	1	221	2	176	1.4e-56	184.1	COG3015	Uncharacterized lipoprotein NlpE involved in copper resistance	178
2904478526	136	53.97	2	136	104	232	1.8e-34	113.5	COG1186	Protein chain release factor B	239
2904478527	186	98.9	1	181	1	179	2.4e-91	298.7	COG4681	Uncharacterized conserved protein YaeQ, suppresses RfaH defect	181
2904478528	66	14.03	3	64	114	144	5.2e-04	14	COG4649	Uncharacterized protein	221
2904478529	86	98.81	3	86	1	83	1.0e-43	141.9	COG4568	Transcriptional antiterminator Rof (Rho-off)	84
2904478530	109	69.63	2	109	21	114	7.7e-28	91.6	COG2863	Cytochrome c553	121
2904478531	447	96.75	7	306	8	305	1.3e-67	222.1	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
2904478532	129	99.32	5	128	2	146	1.2e-21	72.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2904478533	715	99.49	121	711	2	591	0.0e+00	771.4	COG1982	Arginine/lysine/ornithine decarboxylase	557
2904478534	319	98.74	2	319	2	314	0.0e+00	512.1	COG0825	Acetyl-CoA carboxylase alpha subunit	317
2904478535	1160	99.83	3	1158	2	1156	0.0e+00	1508.6	COG0587	DNA polymerase III, alpha subunit	1139
2904478536	198	94.55	12	198	2	192	1.3e-71	235.3	COG0164	Ribonuclease HII	199
2904478537	382	99.47	5	382	2	379	0.0e+00	495.2	COG0763	Lipid A disaccharide synthetase	381
2904478538	262	99.62	3	262	2	260	1.1e-122	402.6	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
2904478539	151	97.97	5	151	2	146	2.9e-60	196.7	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2904478540	340	99.41	1	337	2	337	0.0e+00	467.4	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
2904478541	165	98.24	1	165	2	168	9.1e-52	169.9	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
2904478542	806	100	1	806	1	774	0.0e+00	961.5	COG4775	Outer membrane protein assembly factor BamA	766
2904478543	451	55.47	4	228	2	224	5.5e-125	207.9	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
2904478543	451	63.93	210	451	144	400	5.5e-125	210.3	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
2904478544	282	98.18	1	282	2	271	3.6e-82	270.4	COG0575	CDP-diglyceride synthetase	265
2904478545	252	94.05	1	243	16	252	9.0e-100	327.5	COG0020	Undecaprenyl pyrophosphate synthase	245
2904478546	398	98.96	1	397	1	382	0.0e+00	561.3	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
2904478547	185	97.86	1	185	4	186	7.5e-80	261.1	COG0233	Ribosome recycling factor	187
2904478548	243	99.16	6	241	2	237	5.2e-99	324.9	COG0528	Uridylate kinase	238
2904478549	283	100	1	282	1	297	8.0e-117	383.8	COG0264	Translation elongation factor EF-Ts	296
2904478550	241	88.67	1	241	6	232	7.1e-108	353.8	COG0052	Ribosomal protein S2	252
2904478552	263	99.68	1	254	1	309	1.7e-91	301	COG0024	Methionine aminopeptidase	255
2904478553	896	99.31	28	896	5	865	0.0e+00	1242.2	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
2904478554	274	99.63	1	273	1	271	2.0e-108	356.4	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
2904478556	149	98.69	1	148	1	151	5.2e-28	92.7	COG0716	Flavodoxin	151
2904478557	259	70.89	1	225	83	289	1.4e-67	222.3	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2904478558	104	96.33	1	104	1	105	2.2e-39	128.5	COG3098	Uncharacterized conserved protein YqcC, DUF446 family	109
2904478559	412	51.7	217	410	9	206	6.9e-42	35.5	COG0477	MFS family permease	338
2904478559	412	76.24	14	258	3	294	6.9e-42	111.5	COG0477	MFS family permease	338
2904478562	281	99.27	2	138	1	136	7.5e-67	217	COG2904	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, N-terminal domain	137
2904478563	454	95.61	131	347	3	198	2.5e-55	181.2	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2904478564	250	74.31	2	249	37	279	5.3e-64	210.8	COG0258	5'-3' exonuclease	310
2904478565	368	99.72	1	358	1	357	0.0e+00	646.6	COG2933	23S rRNA C2498 (ribose-2'-O)-methylase RlmM	358
2904478566	131	98.39	2	126	2	123	8.6e-47	152.7	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
2904478567	306	98.67	6	298	2	298	6.3e-70	230.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904478569	74	31.71	1	72	1	39	1.9e-03	12.8	COG5633	Uncharacterized conserved protein YcfL	123
2904478570	401	98.29	1	399	3	404	0.0e+00	463.3	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
2904478571	144	96.53	2	144	3	141	1.2e-47	155.5	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
2904478572	271	98.48	1	268	4	263	9.7e-120	393	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
2904478573	370	98.42	1	362	1	373	0.0e+00	442.1	COG2821	Membrane-bound lytic murein transglycosylase	373
2904478577	392	95.49	30	386	12	265	1.6e-80	264.7	COG0860	N-acetylmuramoyl-L-alanine amidase	231
2904478578	441	94.77	295	441	1	145	5.9e-58	188.6	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
2904478578	441	100	23	291	1	265	3.4e-93	305.7	COG0548	Acetylglutamate kinase	265
2904478579	961	99.26	22	958	4	938	0.0e+00	1086.5	COG1025	Secreted/periplasmic Zn-dependent peptidases, insulinase-like	937
2904478580	114	64.24	1	112	8	113	5.0e-17	56.6	COG4967	Tfp pilus assembly protein PilV	162
2904478582	195	94.03	1	194	6	194	2.0e-42	139.7	COG4795	Type II secretory pathway, component PulJ	194
2904478583	153	90.38	1	148	10	150	1.3e-06	23.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
2904478584	264	99.27	1	264	3	273	1.9e-129	425	COG0207	Thymidylate synthase	268
2904478585	289	97.22	1	288	1	280	2.6e-106	348.9	COG0682	Prolipoprotein diacylglyceryltransferase	287
2904478586	735	98.15	1	735	15	756	0.0e+00	1158.8	COG3605	Signal transduction protein containing GAF and PtsI domains	756
2904478587	175	87.79	2	152	12	162	1.7e-24	80.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2904478588	228	99.13	1	228	1	227	4.4e-130	426	COG3066	DNA mismatch repair protein MutH	229
2904478590	346	98.75	1	346	1	316	1.1e-107	354	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2904478591	391	96.61	2	387	3	372	5.1e-17	56.4	COG0477	MFS family permease	338
2904478592	721	81.23	1	216	37	248	1.4e-25	83.8	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2904478592	721	98.06	198	720	3	559	6.1e-84	276.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2904478594	752	93.09	6	752	53	806	0.0e+00	509.7	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2904478595	335	99.1	2	333	1	331	1.2e-109	361	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904478596	149	70.76	1	141	7	127	1.7e-11	38.6	COG3153	Predicted N-acetyltransferase YhbS	171
2904478597	257	94.19	5	238	8	234	7.6e-60	196.4	COG2186	DNA-binding transcriptional regulator, FadR family	241
2904478598	105	99.02	1	105	1	101	3.7e-35	114.5	COG1440	Phosphotransferase system cellobiose-specific component IIB	102
2904478599	478	98.27	5	472	3	457	4.1e-130	428.8	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2904478600	447	97.24	1	446	8	429	2.5e-130	429.3	COG1455	Phosphotransferase system cellobiose-specific component IIC	432
2904478601	105	94.29	1	105	4	102	2.5e-32	105.5	COG1447	Phosphotransferase system cellobiose-specific component IIA	105
2904478602	419	97.47	2	397	11	395	4.8e-113	372	COG0019	Diaminopimelate decarboxylase	394
2904478603	307	98.34	4	299	2	297	3.0e-55	182.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904478604	387	97.22	1	383	10	393	0.0e+00	430.5	COG2814	Predicted arabinose efflux permease, MFS family	394
2904478605	305	98.01	2	297	6	300	3.1e-63	208.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904478606	289	78.46	21	272	29	232	1.1e-19	64.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2904478607	238	22.83	11	195	134	217	1.8e-04	16.3	COG0457	Tetratricopeptide (TPR) repeat	291
2904478608	581	94.07	1	579	25	595	0.0e+00	646.6	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
2904478609	246	97.91	1	242	5	238	2.9e-61	201.3	COG2188	DNA-binding transcriptional regulator, GntR family	236
2904478610	533	86.52	453	532	3	79	1.2e-18	61.4	COG1264	Phosphotransferase system IIB components	88
2904478610	533	95.95	1	456	11	413	1.7e-113	374	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
2904478611	377	94.87	1	358	13	382	1.0e-68	226.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904478612	1049	99.61	1	1028	2	1011	0.0e+00	1143.4	COG0841	Multidrug efflux pump subunit AcrB	1009
2904478613	467	97.61	16	467	2	450	1.2e-128	424.1	COG1538	Outer membrane protein TolC	457
2904478614	85	97.75	1	85	2	88	1.2e-22	74.3	COG3077	Antitoxin component of the RelBE or YafQ-DinJ toxin-antitoxin module	88
2904478615	89	86.59	1	82	3	73	7.8e-37	119.3	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
2904478616	122	87.6	2	121	13	125	3.1e-31	102.2	COG2852	Very-short-patch-repair endonuclease	129
2904478618	482	98.26	32	482	1	452	5.1e-116	382.5	COG1538	Outer membrane protein TolC	457
2904478619	1041	99.9	2	1017	1	1013	0.0e+00	1091.7	COG0841	Multidrug efflux pump subunit AcrB	1009
2904478620	1066	99.7	2	1050	3	1013	0.0e+00	1113.5	COG0841	Multidrug efflux pump subunit AcrB	1009
2904478621	447	95.64	4	400	9	381	7.7e-74	243	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904478622	276	98.77	6	252	2	242	2.8e-68	224.2	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
2904478623	181	54.55	17	181	95	226	1.9e-35	117	COG1876	LD-carboxypeptidase LdcB, LAS superfamily	241
2904478624	184	89.3	4	184	15	181	2.5e-33	110.1	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2904478625	394	98.23	1	392	5	392	7.3e-116	381.3	COG2814	Predicted arabinose efflux permease, MFS family	394
2904478626	138	54.81	1	96	5	78	7.3e-04	14	COG4954	Uncharacterized protein	135
2904478627	158	94.94	1	155	1	150	1.5e-39	129.9	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2904478628	367	95.17	2	367	14	387	1.1e-82	272.3	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2904478629	155	88.89	3	155	17	160	2.6e-38	125.9	COG0700	Spore maturation protein SpmB (function unknown)	162
2904478630	226	52.46	6	222	109	332	2.1e-26	86.8	COG3314	Uncharacterized membrane protein YjiH, contains nucleoside recognition GATE domain	427
2904478631	379	95.69	5	376	15	414	1.6e-53	176.4	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2904478632	304	97.34	6	304	5	297	1.3e-45	150.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904478633	453	98.51	8	428	4	400	0.0e+00	468.2	COG0137	Argininosuccinate synthase	403
2904478634	83	95.12	1	80	4	81	5.1e-38	123.2	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
2904478636	509	98.82	1	507	6	508	0.0e+00	742.7	COG1190	Lysyl-tRNA synthetase (class II)	502
2904478637	364	99.16	127	364	1	237	3.8e-116	380.8	COG1186	Protein chain release factor B	239
2904478638	577	95.63	35	554	7	488	0.0e+00	540.2	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
2904478639	225	85.54	2	218	34	246	5.4e-44	144.9	COG1651	Protein-disulfide isomerase	244
2904478640	319	99	21	319	4	300	0.0e+00	431.8	COG4974	Site-specific recombinase XerD	300
2904478641	172	98.69	1	168	2	152	4.4e-41	135.1	COG0716	Flavodoxin	151
2904478643	94	91.49	1	91	7	92	4.2e-33	107.5	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
2904478644	330	99.68	7	328	2	308	3.5e-87	287.1	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
2904478645	176	98.88	2	171	2	178	8.2e-26	85.2	COG1437	Adenylate cyclase class IV, CYTH domain (includes archaeal enzymes of unknown function)	178
2904478646	314	98.39	3	312	1	305	2.7e-97	319.6	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
2904478648	295	81.82	1	136	18	125	2.7e-24	79.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904478648	295	100	137	295	1	154	2.5e-46	150.9	COG3449	DNA gyrase inhibitor GyrI	154
2904478650	398	49.87	211	396	5	195	1.4e-20	32	COG0477	MFS family permease	338
2904478650	398	71.8	9	242	2	276	1.4e-20	40	COG0477	MFS family permease	338
2904478651	101	95.19	1	101	6	104	3.1e-33	109	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2904478653	483	98.68	14	483	2	451	2.3e-128	423.1	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2904478654	143	69.35	4	143	53	181	2.3e-37	123.2	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2904478655	79	97.5	1	76	1	78	7.4e-18	58.9	COG0695	Glutaredoxin	80
2904478656	134	93.01	1	134	3	135	4.4e-61	199.2	COG1780	Protein involved in ribonucleotide reduction	141
2904478657	720	99.48	16	719	4	762	0.0e+00	685.1	COG0209	Ribonucleotide reductase alpha subunit	696
2904478658	327	93.86	1	325	20	340	1.1e-98	324.7	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
2904478659	347	97.81	14	339	1	313	7.1e-100	328.2	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2904478660	152	52.21	7	146	120	249	2.9e-39	130.1	COG0791	Cell wall-associated hydrolase, NlpC family	197
2904478661	451	97.27	11	450	12	438	4.2e-130	428.5	COG3493	Na+/citrate or Na+/malate symporter	438
2904478662	550	98.7	1	544	4	533	0.0e+00	506	COG3290	Sensor histidine kinase regulating citrate/malate metabolism	537
2904478663	237	98.66	7	231	2	222	4.8e-71	233	COG4565	Response regulator of citrate/malate metabolism	224
2904478664	398	99.48	1	395	2	387	0.0e+00	577.3	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
2904478665	399	96.91	95	384	7	288	3.8e-121	398	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
2904478666	336	96.39	4	336	10	303	1.2e-85	281.5	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
2904478667	331	98.36	1	331	4	303	3.9e-95	312.7	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
2904478668	60	89.39	1	60	7	65	3.9e-13	43.5	COG1724	Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family	66
2904478669	143	43.84	9	75	25	56	1.5e-05	18.7	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
2904478670	394	96.71	1	392	3	384	6.9e-38	124.4	COG2814	Predicted arabinose efflux permease, MFS family	394
2904478671	253	93.72	6	247	10	233	2.4e-68	224.3	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
2904478672	112	94.39	1	109	3	103	7.7e-08	26.7	COG4392	Branched-chain amino acid transport protein	107
2904478673	173	91.73	25	164	11	132	2.9e-25	83	COG1846	DNA-binding transcriptional regulator, MarR family	126
2904478674	484	98.7	15	484	2	455	5.3e-94	309.9	COG1538	Outer membrane protein TolC	457
2904478675	391	96.59	7	363	6	345	4.1e-124	407.8	COG1566	Multidrug resistance efflux pump	352
2904478676	511	51.7	260	508	9	206	5.3e-46	22.6	COG0477	MFS family permease	338
2904478676	511	72.58	9	279	3	280	5.3e-46	133.3	COG0477	MFS family permease	338
2904478677	367	95.06	108	367	12	261	2.1e-73	241	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2904478678	139	28.2	25	139	44	129	6.6e-30	99.1	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2904478679	234	98.7	2	234	2	229	3.0e-98	322.3	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
2904478680	906	75.4	707	878	14	154	1.5e-10	35.1	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2904478680	906	100	3	625	1	634	0.0e+00	737.9	COG1042	Acyl-CoA synthetase (NDP forming)	598
2904478681	452	90.72	1	452	42	481	3.8e-70	231.2	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2904478682	432	48.83	238	431	8	194	7.2e-41	31.7	COG0477	MFS family permease	338
2904478682	432	63.45	18	276	7	249	7.2e-41	110	COG0477	MFS family permease	338
2904478683	179	97.71	1	175	1	171	1.3e-79	260.2	COG4635	Protoporphyrinogen IX oxidase, menaquinone-dependent (flavodoxin domain)	175
2904478684	483	97.86	1	483	1	503	0.0e+00	487.3	COG0168	Trk-type K+ transport system, membrane component	499
2904478685	203	96.04	1	200	2	195	1.4e-60	198.2	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
2904478686	443	94.62	9	442	13	381	5.1e-58	190	COG0006	Xaa-Pro aminopeptidase	384
2904478687	730	23.71	607	713	188	265	1.8e-121	31.1	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2904478687	730	94.72	4	302	7	257	2.8e-62	204	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2904478687	730	97.57	311	649	3	323	1.8e-121	375.5	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2904478688	387	99.75	1	387	1	393	0.0e+00	473.6	COG0183	Acetyl-CoA acetyltransferase	392
2904478689	233	93	1	232	9	247	9.6e-61	199.4	COG0543	NAD(P)H-flavin reductase	252
2904478690	496	99.59	1	489	1	481	0.0e+00	754.5	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
2904478691	241	93.75	1	214	1	210	5.3e-39	128	COG3340	Peptidase E	224
2904478692	162	98.91	1	162	2	182	5.4e-22	72.6	COG0250	Transcription antitermination factor NusG	178
2904478693	259	98.83	1	255	3	256	1.5e-70	231.8	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
2904478694	255	96.53	1	252	4	253	1.3e-94	310.7	COG0805	Sec-independent protein secretion pathway component TatC	255
2904478695	215	42.55	71	185	27	66	2.3e-23	6.6	COG1826	Sec-independent protein translocase protein TatA	94
2904478695	215	94.68	1	102	2	90	2.3e-23	77	COG1826	Sec-independent protein translocase protein TatA	94
2904478696	88	92.55	1	88	1	87	4.0e-23	76.1	COG1826	Sec-independent protein translocase protein TatA	94
2904478697	543	98.63	1	517	4	508	0.0e+00	614	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
2904478698	204	98.04	1	204	2	201	7.2e-76	248.6	COG3165	Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain	204
2904478699	251	99.58	13	251	1	238	7.8e-103	337	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2904478700	513	93.32	53	500	17	435	0.0e+00	503	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
2904478701	175	78.85	6	175	6	169	1.6e-43	142.9	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2904478702	253	98.79	1	253	4	248	7.2e-111	363.5	COG2820	Uridine phosphorylase	248
2904478703	760	97.6	71	580	9	497	0.0e+00	742.3	COG0753	Catalase	496
2904478704	275	98.73	36	275	2	235	6.7e-87	285.1	COG0412	Dienelactone hydrolase	236
2904478705	220	96.71	1	220	8	301	4.7e-54	173.6	COG0176	Transaldolase	239
2904478706	834	94.38	2	91	3	86	2.1e-20	66.1	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
2904478706	834	96.71	686	834	4	150	3.9e-38	123.9	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
2904478706	834	98.95	117	686	4	571	0.0e+00	706.1	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
2904478707	359	98.55	10	349	2	340	1.0e-125	413.5	COG1299	Phosphotransferase system, fructose-specific IIC component	343
2904478708	109	85.25	1	109	2	105	5.2e-44	143.7	COG1445	Phosphotransferase system fructose-specific component IIB	122
2904478709	765	99.47	1	765	5	755	0.0e+00	804.8	COG1882	Pyruvate-formate lyase	755
2904478710	295	96.37	20	294	4	242	3.9e-66	216.8	COG1180	Pyruvate-formate lyase-activating enzyme	260
2904478711	114	86.89	2	112	3	108	2.6e-40	131.6	COG1445	Phosphotransferase system fructose-specific component IIB	122
2904478712	287	81.06	132	286	23	129	2.9e-28	92.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904478713	759	87.92	10	339	17	307	0.0e+00	46.8	COG0620	Methionine synthase II (cobalamin-independent)	330
2904478713	759	99.7	426	757	2	331	0.0e+00	470.2	COG0620	Methionine synthase II (cobalamin-independent)	330
2904478714	311	98.67	2	294	2	298	7.4e-64	210.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904478715	299	95.35	1	286	10	296	9.2e-40	131	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2904478716	100	33.63	3	99	124	199	8.5e-03	10.2	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
2904478718	246	95.2	1	245	7	264	4.1e-52	171.8	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2904478719	357	99.71	1	351	1	349	0.0e+00	468.6	COG3839	ABC-type sugar transport system, ATPase component	338
2904478720	281	95.41	1	281	10	279	3.2e-90	296.7	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2904478721	295	95.64	3	295	10	294	9.6e-82	268.9	COG1175	ABC-type sugar transport system, permease component	295
2904478722	437	97.74	1	432	10	442	5.9e-82	270.7	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2904478723	159	97.47	1	159	1	154	2.3e-33	109.6	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2904478726	395	86.84	1	395	55	450	9.6e-120	394.7	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2904478727	233	98.73	1	233	3	236	9.4e-103	336.7	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2904478728	256	99.61	2	255	2	254	1.6e-112	369.2	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2904478729	429	97.83	85	415	6	321	2.3e-109	360	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2904478730	308	99	4	307	3	300	2.3e-98	323.7	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2904478731	370	95.9	15	369	5	355	4.5e-93	306.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2904478732	126	32.72	5	125	62	114	2.0e-03	13.5	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904478733	285	78.59	1	285	63	330	1.8e-93	308.1	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2904478734	326	99.33	25	326	2	296	3.6e-109	358.6	COG2177	Cell division protein FtsX	297
2904478735	220	96.86	1	219	1	216	5.7e-104	340.9	COG2884	ABC-type ATPase involved in cell division	223
2904478736	493	86.11	11	490	50	359	0.0e+00	429.7	COG0552	Signal recognition particle GTPase	340
2904478737	203	98.94	12	192	1	186	4.5e-66	216.2	COG0742	16S rRNA G966 N2-methylase RsmD	187
2904478738	92	93.41	1	91	3	87	4.1e-32	104.6	COG3776	Uncharacterized conserved protein YhhL, DUF1145 family	91
2904478739	208	99.06	1	208	2	211	2.5e-67	221.1	COG3714	Uncharacterized membrane protein YhhN	212
2904478740	784	99.45	91	784	3	729	0.0e+00	737.6	COG2217	Cation transport ATPase	713
2904478741	86	92.5	5	81	5	78	6.1e-27	87.7	COG0425	TusA-related sulfurtransferase	78
2904478742	223	96.9	1	215	5	223	1.2e-79	261.2	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
2904478744	450	99.11	1	449	2	447	0.0e+00	643.2	COG2271	Sugar phosphate permease	448
2904478746	358	99.71	1	349	1	349	0.0e+00	443.9	COG3839	ABC-type sugar transport system, ATPase component	338
2904478747	454	94.77	1	452	12	464	4.9e-115	379.2	COG1109	Phosphomannomutase	464
2904478748	327	95.51	1	327	12	330	4.1e-69	227.6	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904478749	420	99.1	1	420	4	442	3.2e-49	162.9	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2904478750	290	93.96	2	289	14	293	3.0e-60	198.3	COG1175	ABC-type sugar transport system, permease component	295
2904478751	293	95.76	5	293	9	279	9.0e-74	242.6	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2904478752	516	96.32	10	504	2	499	2.1e-96	317.3	COG0366	Glycosidase	505
2904478753	355	97.76	1	353	3	308	1.6e-113	373	COG2152	Predicted glycosyl hydrolase, GH43/DUF377 family	314
2904478755	451	80	1	450	109	556	5.7e-113	372.9	COG2831	Hemolysin activation/secretion protein	554
2904478757	86	10.33	8	74	370	423	2.7e-01	4	COG0342	Preprotein translocase subunit SecD	506
2904478765	269	98.9	1	267	2	270	1.2e-70	232.7	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
2904478766	330	97.4	22	330	4	303	6.1e-80	262.8	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2904478767	206	99.52	1	205	1	207	1.2e-57	188.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2904478768	205	98.56	1	205	2	206	4.4e-56	183.6	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2904478769	610	99.34	8	607	4	601	0.0e+00	828.9	COG0514	Superfamily II DNA helicase RecQ	590
2904478770	292	94.32	1	292	18	316	4.5e-120	395	COG2829	Outer membrane phospholipase A	317
2904478771	160	93.62	6	160	5	136	4.6e-33	108.1	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2904478772	304	98.31	1	295	5	294	7.3e-119	390.7	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
2904478773	355	98.86	2	349	2	349	3.3e-115	378.8	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
2904478774	316	96.04	1	316	14	328	4.2e-72	237	COG0598	Mg2+ and Co2+ transporter CorA	322
2904478775	158	48.09	15	129	46	108	1.0e-05	16.6	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2904478776	720	98.81	8	652	2	664	0.0e+00	778.8	COG0210	Superfamily I DNA or RNA helicase	655
2904478777	238	98.27	7	238	2	228	5.4e-36	118.8	COG1011	FMN phosphatase YigB, HAD superfamily	229
2904478778	303	98.33	3	301	5	298	0.0e+00	490.9	COG4973	Site-specific recombinase XerC	299
2904478779	234	99.08	11	232	3	218	2.7e-84	276.5	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
2904478780	274	99.63	1	274	1	270	9.1e-112	367.2	COG0253	Diaminopimelate epimerase	272
2904478781	67	81.03	1	56	1	47	8.8e-19	61.6	COG5567	Predicted small periplasmic lipoprotein YifL (function unknown0	58
2904478782	852	98.83	1	850	2	844	0.0e+00	1478.7	COG3072	Adenylate cyclase	853
2904478783	313	98.7	3	308	3	305	2.7e-128	421.6	COG0181	Porphobilinogen deaminase	307
2904478784	249	98.4	1	248	2	247	2.4e-62	204.6	COG1587	Uroporphyrinogen-III synthase	248
2904478785	383	94.95	1	383	1	376	0.0e+00	469.6	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
2904478786	398	99.25	1	398	1	397	0.0e+00	542.2	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
2904478792	464	97.84	1	463	4	455	0.0e+00	634.4	COG1113	L-asparagine transporter and related permeases	462
2904478793	246	96.84	1	246	4	248	5.9e-89	291.9	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
2904478796	416	40.25	1	213	7	200	1.3e-39	90.5	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2904478796	416	45.85	199	416	248	468	1.3e-39	46	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2904478797	376	98.13	1	376	5	372	2.7e-127	419.3	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2904478798	236	87.04	85	236	17	157	1.6e-14	48.3	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904478799	420	95.18	1	420	10	424	0.0e+00	566.4	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
2904478800	376	96.35	1	376	4	373	0.0e+00	529.5	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
2904478801	350	96	1	349	10	345	2.3e-113	373.2	COG3765	LPS O-antigen chain length determinant protein, WzzB/FepE family	347
2904478802	312	83.13	1	269	51	321	3.2e-61	201.8	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2904478803	419	98.82	1	419	4	420	0.0e+00	738.5	COG1158	Transcription termination factor Rho	422
2904478804	108	34.43	1	108	24	128	1.1e-26	88.7	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2904478806	425	78.27	1	424	28	434	0.0e+00	463.2	COG0513	Superfamily II DNA and RNA helicase	513
2904478807	496	99.8	4	487	2	495	0.0e+00	521.2	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
2904478808	674	99.4	1	650	2	668	0.0e+00	763.4	COG0210	Superfamily I DNA or RNA helicase	655
2904478809	93	30.15	1	93	169	266	7.0e-30	99	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2904478810	491	39.35	355	489	198	330	0.0e+00	66.8	COG0059	Ketol-acid reductoisomerase	338
2904478810	491	99.11	19	362	2	336	0.0e+00	438.4	COG0059	Ketol-acid reductoisomerase	338
2904478811	293	96.68	1	293	1	291	2.9e-65	215.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904478812	514	97.98	10	349	7	345	0.0e+00	443.2	COG1171	Threonine dehydratase	347
2904478813	616	98.27	1	614	10	577	0.0e+00	792.1	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2904478814	309	99.3	5	296	2	284	3.5e-99	326.6	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2904478815	87	100	1	85	1	86	1.0e-41	135.3	COG3978	Acetolactate synthase small subunit, contains ACT domain	86
2904478816	548	99.64	1	546	2	554	0.0e+00	711.1	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2904478818	412	50.65	204	403	9	202	4.3e-43	45.8	COG0477	MFS family permease	338
2904478818	412	68.93	3	239	8	271	4.3e-43	103.6	COG0477	MFS family permease	338
2904478819	511	99.8	15	502	1	491	0.0e+00	648.4	COG0606	Predicted ATPase with chaperone activity	490
2904478820	79	70.54	1	79	34	112	6.6e-36	117.5	COG3085	Uncharacterized conserved protein YifE, UPF0438 family	112
2904478821	203	72.43	1	197	74	291	2.3e-17	57.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904478822	328	95.3	1	321	9	312	2.1e-79	261	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2904478823	332	94.04	6	330	13	312	1.2e-80	265.1	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2904478824	502	99	4	502	5	500	0.0e+00	605.5	COG1129	ABC-type sugar transport system, ATPase component	500
2904478825	318	94.8	1	316	13	322	4.0e-76	250.2	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2904478828	177	96.91	5	169	2	158	2.3e-47	155.5	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
2904478829	195	97.42	3	190	3	191	3.9e-60	196.9	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
2904478830	89	100	1	88	1	88	1.8e-45	147.8	COG3084	Uncharacterized protein YihD, DUF1040 family	88
2904478831	328	99.7	1	325	1	334	4.6e-82	269.8	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2904478832	207	63.05	13	201	76	232	4.6e-11	35.7	COG1651	Protein-disulfide isomerase	244
2904478833	934	93.88	1	312	9	315	5.6e-98	322.1	COG0258	5'-3' exonuclease	310
2904478833	934	99.66	333	934	3	597	0.0e+00	842.7	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
2904478835	216	98	5	203	3	198	1.5e-75	247.4	COG0218	GTP-binding protein EngB required for normal cell division	200
2904478836	183	99.41	1	174	1	169	8.0e-55	179.6	COG3078	Ribosome assembly protein YihI, activator of Der GTPase	169
2904478837	457	99.52	14	447	2	419	0.0e+00	485.7	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
2904478838	470	97.43	1	470	6	460	0.0e+00	646.9	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904478839	349	97.25	1	349	4	356	0.0e+00	521.4	COG3852	Signal transduction histidine kinase, nitrogen specific	363
2904478840	469	99.55	1	469	2	445	0.0e+00	585.6	COG0174	Glutamine synthetase	443
2904478841	607	99.5	1	604	2	601	0.0e+00	1044.1	COG1217	Predicted membrane GTPase involved in stress response	603
2904478842	195	85.71	1	193	6	203	1.7e-33	110.8	COG1011	FMN phosphatase YigB, HAD superfamily	229
2904478843	289	93.07	1	289	14	295	2.1e-77	254.8	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2904478844	145	100	1	145	1	145	2.8e-65	213.5	COG1490	D-Tyr-tRNAtyr deacylase	145
2904478845	310	57.52	23	135	33	120	1.5e-11	38.2	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
2904478845	310	92.2	158	301	10	139	1.6e-06	20.1	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2904478847	463	95.83	16	463	5	441	0.0e+00	501.2	COG2233	Xanthine/uracil permease	451
2904478848	403	99.51	1	401	2	405	0.0e+00	528.3	COG0786	Na+/glutamate symporter	404
2904478849	413	93.78	1	404	26	432	3.5e-124	409	COG1455	Phosphotransferase system cellobiose-specific component IIC	432
2904478850	693	98.97	1	686	6	676	0.0e+00	905.8	COG1200	RecG-like helicase	677
2904478851	232	63.12	1	168	97	262	1.6e-49	162	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2904478852	702	98.76	2	700	9	723	0.0e+00	979.3	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2904478853	91	97.3	1	73	1	72	1.1e-28	93.3	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
2904478854	207	96.41	1	198	5	192	9.5e-85	277.5	COG0194	Guanylate kinase	191
2904478855	567	86.05	29	566	4	583	6.5e-102	336	COG0272	NAD-dependent DNA ligase	667
2904478856	205	97.61	1	205	4	207	1.3e-84	277.4	COG2860	Uncharacterized membrane protein YeiH	209
2904478857	206	86.12	8	206	9	188	8.2e-24	79.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904478858	424	99.28	2	423	3	413	0.0e+00	502.1	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2904478859	287	100	1	287	1	290	5.7e-117	384.8	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
2904478860	238	96.97	1	237	8	231	5.0e-102	334.5	COG0689	Ribonuclease PH	230
2904478861	213	99.51	3	211	2	203	4.9e-73	239.5	COG0461	Orotate phosphoribosyltransferase	201
2904478862	735	98.29	44	731	1	633	3.4e-96	317.6	COG4984	Uncharacterized membrane protein	644
2904478863	178	97.89	1	177	4	189	3.6e-39	128.7	COG4929	Uncharacterized membrane-anchored protein	190
2904478864	198	70.33	1	190	6	152	5.7e-22	73.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904478865	152	99.33	2	152	1	148	1.5e-60	197.5	COG0756	dUTPase	148
2904478866	406	99.5	5	401	2	400	0.0e+00	486.7	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
2904478867	226	98.66	3	226	4	224	6.8e-86	281.7	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
2904478868	66	81.82	1	64	14	76	2.7e-28	92.4	COG0227	Ribosomal protein L28	77
2904478869	55	100	3	53	1	51	8.7e-28	90.9	COG0267	Ribosomal protein L33	50
2904478870	269	100	1	269	1	274	1.4e-106	350.7	COG0266	Formamidopyrimidine-DNA glycosylase	273
2904478871	160	98.74	1	159	2	158	5.1e-71	232.1	COG0669	Phosphopantetheine adenylyltransferase	159
2904478872	255	27.86	3	192	3	102	8.0e-22	73.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2904478873	403	94.98	1	398	22	418	0.0e+00	529.5	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
2904478874	381	96.33	8	381	12	405	1.2e-32	108.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904478875	342	97.06	1	342	7	336	2.6e-86	284.5	COG0859	ADP-heptose:LPS heptosyltransferase	334
2904478876	335	66.85	8	333	2	241	1.2e-33	111.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2904478877	428	89.98	7	415	24	409	6.4e-14	45.4	COG3307	O-antigen ligase	424
2904478878	334	81.42	27	332	4	279	6.5e-61	200.7	COG1442	Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase	325
2904478879	365	85.59	26	331	5	295	6.0e-30	98.9	COG0859	ADP-heptose:LPS heptosyltransferase	334
2904478880	329	99.12	1	324	2	338	3.2e-85	280.9	COG0859	ADP-heptose:LPS heptosyltransferase	334
2904478881	349	99.12	1	347	2	338	1.1e-98	325.1	COG0859	ADP-heptose:LPS heptosyltransferase	334
2904478882	310	98.13	1	309	2	316	3.7e-71	234.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2904478883	398	99.49	3	391	2	389	0.0e+00	474.4	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
2904478884	340	100	1	340	1	353	1.8e-102	337	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2904478886	407	94.62	5	405	12	398	1.8e-31	104.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904478887	264	78.04	1	204	54	252	7.4e-84	274.9	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
2904478888	430	94.84	10	430	22	425	0.0e+00	489.7	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
2904478889	514	99.61	3	513	2	508	0.0e+00	776.8	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
2904478890	143	95.61	35	143	5	113	3.1e-26	85.9	COG0607	Rhodanese-related sulfurtransferase	110
2904478891	83	98.75	2	79	2	80	2.5e-28	92.6	COG0695	Glutaredoxin	80
2904478892	156	97.45	1	155	4	156	5.2e-71	231.8	COG1952	Preprotein translocase subunit SecB	157
2904478893	339	99.7	5	335	2	329	0.0e+00	432.5	COG0240	Glycerol-3-phosphate dehydrogenase	329
2904478894	273	95.41	71	268	7	193	2.2e-81	266.1	COG1045	Serine acetyltransferase	194
2904478895	157	98.7	1	154	1	152	2.8e-70	229.5	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
2904478896	456	81.73	104	456	68	389	2.3e-66	219.5	COG0642	Signal transduction histidine kinase	336
2904478897	233	98.71	2	233	2	230	1.4e-83	274.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904478898	169	90.62	1	158	9	153	7.8e-38	124.6	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
2904478899	328	98.04	1	328	1	350	5.7e-123	404.7	COG0205	6-phosphofructokinase	347
2904478900	329	90.26	4	329	31	345	0.0e+00	548.8	COG1613	ABC-type sulfate transport system, periplasmic component	348
2904478901	255	99.6	1	253	1	251	8.4e-102	334.3	COG0149	Triosephosphate isomerase	251
2904478903	140	93.75	1	140	8	142	8.3e-38	124	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
2904478904	248	99.25	1	248	3	268	1.6e-57	189.3	COG1018	Ferredoxin-NADP reductase	266
2904478905	397	73.37	4	273	5	285	8.9e-25	82.4	COG0477	MFS family permease	338
2904478906	336	99.1	1	333	1	330	0.0e+00	517.9	COG1494	Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase or related protein	332
2904478907	507	99	5	505	4	499	0.0e+00	813.5	COG0554	Glycerol kinase	499
2904478908	282	97.96	3	259	5	244	4.0e-82	269.4	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
2904478909	79	100	1	79	1	79	4.0e-41	133.9	COG3074	Cell division protein ZapB, interacts with FtsZ	79
2904478910	161	78.77	1	161	8	174	6.2e-57	187	COG0684	Regulator of RNase E activity RraA	210
2904478911	308	96.37	8	308	8	299	1.7e-106	350	COG1575	1,4-dihydroxy-2-naphthoate octaprenyltransferase	303
2904478912	444	100	1	444	1	444	0.0e+00	755.9	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
2904478913	176	96.63	1	175	5	176	2.4e-89	292	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
2904478914	280	52.06	150	280	128	266	1.1e-78	135.7	COG3087	Cell division protein FtsN	264
2904478914	280	56.55	1	163	18	168	1.1e-78	128.5	COG3087	Cell division protein FtsN	264
2904478915	342	99.7	10	341	1	333	1.8e-119	393.3	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904478916	731	99.86	1	731	1	733	0.0e+00	930.4	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
2904478917	70	92	1	70	1	69	6.2e-32	104.2	COG0254	Ribosomal protein L31	75
2904478918	105	100	1	105	1	105	9.3e-70	225.8	COG3060	Transcriptional regulator of met regulon	105
2904478919	386	97.98	1	384	8	396	0.0e+00	491.9	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2904478920	811	98.2	457	811	2	329	6.8e-98	322.3	COG0460	Homoserine dehydrogenase	333
2904478920	811	99.1	9	456	4	442	1.3e-106	351.2	COG0527	Aspartokinase	447
2904478921	302	98.98	9	294	4	293	2.7e-113	372.3	COG0685	5,10-methylenetetrahydrofolate reductase	291
2904478922	881	99.89	1	881	2	913	0.0e+00	1261.6	COG2352	Phosphoenolpyruvate carboxylase	910
2904478923	381	96.89	1	381	13	417	2.1e-82	271.9	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2904478924	334	97.71	1	334	2	342	6.3e-127	417.8	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
2904478925	257	98.87	1	257	3	264	8.2e-86	281.8	COG0548	Acetylglutamate kinase	265
2904478926	457	98.91	1	457	4	457	0.0e+00	673.3	COG0165	Argininosuccinate lyase	459
2904478927	253	91.25	171	247	2	74	4.8e-21	68.6	COG0695	Glutaredoxin	80
2904478927	253	98.8	2	163	3	166	5.4e-76	247.7	COG0678	Peroxiredoxin	165
2904478928	307	98.34	1	299	1	296	2.6e-73	241.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904478929	466	99.56	3	458	3	455	0.0e+00	476.7	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2904478930	226	89.47	1	198	7	193	1.1e-21	72.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904478931	119	41.81	10	119	47	143	6.2e-04	13.6	COG0670	Integral membrane protein, interacts with FtsH	233
2904478933	528	96.99	1	478	5	455	4.6e-101	332.9	COG2211	Na+/melibiose symporter or related transporter	467
2904478934	379	98.04	28	379	3	352	1.7e-121	399.9	COG4225	Rhamnogalacturonyl hydrolase YesR	357
2904478935	366	82.34	1	359	78	436	9.2e-101	332.3	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
2904478937	625	100	3	625	1	613	0.0e+00	844.4	COG4206	Outer membrane cobalamin receptor protein	608
2904478938	293	97.01	22	293	4	263	5.1e-91	298.9	COG0796	Glutamate racemase	269
2904478941	282	98.95	2	282	3	286	4.5e-122	401.4	COG0788	Formyltetrahydrofolate hydrolase	287
2904478942	154	99.34	1	154	2	151	1.2e-65	214.8	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
2904478943	303	90.6	1	301	8	296	3.4e-83	274.1	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2904478944	337	91.73	3	161	4	125	1.6e-32	106	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2904478945	447	100	1	425	1	418	0.0e+00	544.5	COG1004	UDP-glucose 6-dehydrogenase	414
2904478946	335	99.07	1	335	2	319	8.0e-93	305.9	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2904478947	135	99.22	7	135	1	127	1.3e-54	178.6	COG2916	DNA-binding protein H-NS	128
2904478948	213	95.52	10	206	3	194	8.4e-78	255	COG1435	Thymidine kinase	201
2904478949	889	92.28	1	445	36	477	3.1e-82	270.7	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2904478949	889	100	451	862	1	379	0.0e+00	494.9	COG1454	Alcohol dehydrogenase, class IV	377
2904478950	214	96.59	6	213	7	204	2.9e-73	239.9	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
2904478951	546	99.3	3	545	4	573	0.0e+00	570.7	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2904478952	306	99.37	1	306	1	316	1.1e-110	364.4	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904478953	302	94.63	9	302	15	296	4.6e-97	318.9	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904478954	341	95.38	23	337	1	310	0.0e+00	431.6	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2904478955	345	95.62	19	334	2	307	3.8e-124	408.4	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2904478957	107	99.07	1	107	2	108	1.8e-58	190.1	COG3099	Uncharacterized conserved protein YciU, UPF0263 family	108
2904478958	486	99.79	47	486	1	484	7.4e-107	352.4	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2904478960	53	59.02	6	49	22	57	2.4e-06	21.9	COG2888	Predicted RNA-binding protein involved in translation, contains  Zn-ribbon domain, DUF1610 family	61
2904478961	96	97.73	1	96	3	88	7.8e-30	97.5	COG3809	Predicted nucleic acid-binding protein, contains Zn-finger domain	88
2904478962	98	100	1	98	1	92	1.1e-33	110	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
2904478963	243	97.08	10	239	7	272	2.2e-35	116.8	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2904478965	146	80.89	1	140	4	130	3.2e-53	173.9	COG1607	Acyl-CoA hydrolase	157
2904478966	179	98.89	1	179	1	178	2.7e-80	263.3	COG2917	Intracellular septation protein A	180
2904478968	77	44.37	1	69	61	123	2.8e-08	28.6	COG0727	Fe-S-cluster containining protein	132
2904478969	210	97.71	1	210	6	218	2.4e-79	260.5	COG3047	Outer membrane protein W	213
2904478970	104	38.58	12	104	120	195	1.4e-23	78.5	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2904478971	268	99.62	1	268	1	264	1.9e-104	342.7	COG0159	Tryptophan synthase alpha chain	265
2904478972	396	98.23	1	396	5	393	0.0e+00	670.5	COG0133	Tryptophan synthase beta chain	396
2904478973	454	99.04	256	454	2	208	5.4e-65	212.1	COG0135	Phosphoribosylanthranilate isomerase	208
2904478973	454	99.61	7	256	1	253	4.4e-103	337.1	COG0134	Indole-3-glycerol phosphate synthase	254
2904478974	337	97.35	3	337	5	335	3.2e-129	425.1	COG0547	Anthranilate phosphoribosyltransferase	338
2904478975	192	98.95	1	190	2	190	5.9e-72	235.6	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
2904478976	520	97.64	10	518	10	465	0.0e+00	518.2	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2904478978	309	98.84	22	284	3	257	1.2e-92	304.5	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
2904478979	206	95.28	2	206	2	203	1.2e-69	228	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
2904478980	439	98.78	149	395	2	244	7.1e-85	278.2	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2904478981	184	98.86	1	182	2	174	1.4e-63	208.1	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
2904478982	250	97.19	3	250	3	244	4.2e-66	217.6	COG0368	Cobalamin synthase	246
2904478983	198	94.26	1	198	3	199	9.7e-57	186.4	COG0406	Broad specificity phosphatase PhoE	208
2904478984	347	94.57	2	346	3	333	3.6e-98	322.9	COG2038	NaMN:DMB phosphoribosyltransferase	347
2904478985	196	99.49	1	196	2	198	7.2e-83	271.6	COG2109	ATP:corrinoid adenosyltransferase	198
2904478986	253	96.27	8	247	3	260	2.4e-52	172.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904478988	347	96.56	33	346	10	318	1.6e-81	268.5	COG0616	Periplasmic serine protease, ClpP class	317
2904478990	865	19.62	575	632	21	51	2.3e-43	17	COG0551	ssDNA-binding Zn-finger and Zn-ribbon domains of topoisomerase 1	140
2904478990	865	98.1	636	858	3	157	2.3e-43	124.1	COG0551	ssDNA-binding Zn-finger and Zn-ribbon domains of topoisomerase 1	140
2904478990	865	99.65	3	594	1	573	0.0e+00	740.2	COG0550	DNA topoisomerase IA	570
2904478991	324	98.67	1	300	1	297	2.9e-60	198.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904478992	890	99.43	4	890	4	868	0.0e+00	1322.6	COG1048	Aconitase A	861
2904478993	196	99.49	1	194	2	196	2.8e-85	279.3	COG0807	GTP cyclohydrolase II	193
2904478994	251	90.09	36	242	5	213	2.2e-26	88	COG0671	Membrane-associated phospholipid phosphatase	232
2904478995	103	94.85	1	97	1	92	3.2e-45	146.8	COG3771	Uncharacterized membrane protein YciS, DUF1049 family	97
2904478996	389	99.74	1	389	1	388	0.0e+00	607.5	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
2904478997	95	35.71	14	80	95	149	4.2e-04	12.9	COG1321	Mn-dependent transcriptional regulator, DtxR family	154
2904478998	242	95	1	242	7	234	2.0e-85	280.3	COG0284	Orotidine-5'-phosphate decarboxylase	240
2904478999	109	97.14	9	109	2	103	1.5e-34	112.6	COG0023	Translation initiation factor 1 (eIF-1/SUI1)	104
2904479000	72	25.7	17	72	68	113	2.8e-01	4.7	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
2904479001	231	98.21	1	231	4	223	1.1e-74	245.1	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2904479002	247	98.03	1	247	4	252	5.2e-74	243.4	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2904479003	810	99.47	5	810	4	754	0.0e+00	903.8	COG1882	Pyruvate-formate lyase	755
2904479004	299	94.76	1	299	7	241	8.6e-77	252	COG1180	Pyruvate-formate lyase-activating enzyme	260
2904479005	221	95.07	1	219	8	296	9.4e-55	177.5	COG0176	Transaldolase	239
2904479007	547	99.2	26	537	3	500	0.0e+00	442.8	COG1070	Sugar (pentulose or hexulose) kinase	502
2904479008	324	98.12	11	324	5	318	1.3e-89	294.6	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
2904479009	520	99.2	11	508	4	500	0.0e+00	550	COG1129	ABC-type sugar transport system, ATPase component	500
2904479010	358	97.81	1	318	4	315	8.2e-91	298.5	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2904479011	341	97.49	1	320	1	311	2.8e-84	277.1	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2904479012	333	92.66	1	312	12	314	6.9e-69	226.5	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2904479013	291	98.14	28	281	4	267	4.5e-85	279.6	COG1830	Fructose-bisphosphate aldolase class Ia, DhnA family	265
2904479014	96	88.89	1	95	5	92	5.2e-26	84.9	COG1359	Quinol monooxygenase YgiN	100
2904479015	483	98.21	1	483	5	497	0.0e+00	547.9	COG1070	Sugar (pentulose or hexulose) kinase	502
2904479016	439	99.32	1	437	4	438	0.0e+00	820.9	COG2115	Xylose isomerase	438
2904479017	328	97.65	1	328	6	338	0.0e+00	471.1	COG4213	ABC-type xylose transport system, periplasmic component	341
2904479018	513	98.6	3	509	6	499	0.0e+00	630.9	COG1129	ABC-type sugar transport system, ATPase component	500
2904479019	399	96.7	14	399	14	394	0.0e+00	528.7	COG4214	ABC-type xylose transport system, permease component	394
2904479020	395	78.74	4	280	68	330	1.4e-44	146.7	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2904479021	774	96.94	8	757	1	760	0.0e+00	780.1	COG1501	Alpha-glucosidase, glycosyl hydrolase family GH31	772
2904479022	455	97.2	1	455	5	456	0.0e+00	509.2	COG2211	Na+/melibiose symporter or related transporter	467
2904479023	357	94.19	1	326	4	311	1.7e-41	136.5	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2904479024	383	91.28	4	383	35	411	8.2e-109	358.6	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2904479025	427	46.48	240	425	8	185	8.1e-31	12.2	COG0477	MFS family permease	338
2904479025	427	71.54	21	270	2	275	8.1e-31	96.4	COG0477	MFS family permease	338
2904479026	473	96.17	8	457	12	413	6.1e-46	151.6	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2904479027	307	97.67	1	299	4	297	3.8e-55	182	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904479028	237	94.34	1	232	5	204	6.1e-38	124.6	COG0560	Phosphoserine phosphatase	212
2904479029	113	99.1	2	112	2	111	1.7e-53	174.1	COG3136	Uncharacterized membrane protein, GlpM family	111
2904479030	403	93.89	4	397	22	390	2.3e-129	426.3	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2904479031	201	76.29	2	198	41	217	1.8e-31	104.4	COG0671	Membrane-associated phospholipid phosphatase	232
2904479032	171	66.14	1	162	39	163	5.7e-13	43.6	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2904479034	370	100	2	370	1	360	1.2e-117	387.4	COG3203	Outer membrane protein (porin)	354
2904479036	106	68.87	11	104	28	100	2.2e-05	18.6	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
2904479040	177	50.2	24	177	121	245	9.8e-12	39.3	COG1651	Protein-disulfide isomerase	244
2904479043	88	100	1	85	1	84	8.0e-28	89.8	COG4115	Toxin component of the Txe-Axe toxin-antitoxin module, Txe/YoeB family	84
2904479044	81	94.19	1	81	3	83	3.0e-23	76	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
2904479045	378	43.28	44	337	57	201	6.3e-07	23.2	COG0582	Integrase	309
2904479046	159	79.01	6	153	26	153	3.4e-07	25.4	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904479047	86	88.42	1	86	9	92	1.2e-30	99.6	COG4453	Uncharacterized conserved protein, DUF1778 family	95
2904479048	113	28.72	1	113	24	133	2.5e-05	18.5	COG0477	MFS family permease	338
2904479049	486	91.8	283	484	14	181	1.1e-46	153	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904479050	1174	72.53	664	769	22	87	4.4e-12	39	COG1144	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit	91
2904479050	1174	97.55	415	623	5	203	4.6e-44	144.3	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
2904479050	1174	99.48	3	398	2	381	1.1e-130	430.3	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
2904479050	1174	99.67	797	1172	2	299	4.3e-100	328.4	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
2904479051	177	98.69	1	176	1	151	1.1e-28	93.8	COG0716	Flavodoxin	151
2904479054	76	24.65	1	75	208	277	9.4e-22	72.2	COG2801	Transposase InsO and inactivated derivatives	232
2904479055	69	22.54	2	69	133	196	1.7e-10	35.2	COG2801	Transposase InsO and inactivated derivatives	232
2904479057	88	6.37	5	86	616	663	3.9e-03	9.9	COG4772	Outer membrane receptor for Fe3+-dicitrate	753
2904479058	88	10.49	2	68	236	278	1.7e-03	11.9	COG3464	Transposase	402
2904479060	211	24.24	1	73	6	69	1.2e-27	51	COG1192	Cellulose biosynthesis protein BcsQ	259
2904479060	211	54.55	58	211	112	255	1.2e-27	40.7	COG1192	Cellulose biosynthesis protein BcsQ	259
2904479066	318	96.01	5	311	2	314	5.3e-54	178	COG3547	Transposase	303
2904479068	412	19.94	10	163	75	139	1.7e-11	11.8	COG3547	Transposase	303
2904479068	412	57.98	185	387	134	322	1.7e-11	28.5	COG3547	Transposase	303
2904479069	207	90.91	1	204	2	191	3.5e-40	132.3	COG0406	Broad specificity phosphatase PhoE	208
2904479070	123	85.04	9	120	15	122	2.0e-06	22.3	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2904479072	176	84.49	1	176	7	164	8.5e-27	89	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2904479073	590	87.43	117	344	17	176	1.3e-03	11.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904479073	590	96.89	330	585	5	253	1.5e-76	250.2	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2904479077	159	66.23	1	155	77	227	6.6e-63	206.6	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
2904479078	424	99.8	45	424	2	510	8.8e-41	130.4	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2904479079	494	92.17	20	494	31	454	2.0e-54	178.7	COG1538	Outer membrane protein TolC	457
2904479080	424	69.6	67	329	50	294	2.1e-31	103.2	COG1566	Multidrug resistance efflux pump	352
2904479085	363	99.15	9	362	3	352	4.3e-126	415.2	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2904479086	264	94.38	1	264	10	261	2.9e-49	162.1	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2904479087	316	98.58	35	316	5	282	5.0e-113	371.5	COG4132	ABC-type uncharacterized transport system, permease component	282
2904479088	369	86.38	59	363	1	260	2.8e-51	168.9	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2904479089	272	98.03	14	263	4	252	6.0e-65	213.5	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2904479090	509	11.72	386	449	412	467	3.7e-24	3.2	COG1524	Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily	450
2904479090	509	56.9	3	302	40	311	3.7e-24	71.2	COG1524	Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily	450
2904479091	297	27.65	23	234	42	122	2.4e-08	28	COG1408	Predicted phosphohydrolase, MPP superfamily	284
2904479092	98	79.8	1	94	2	80	2.4e-23	76.1	COG1359	Quinol monooxygenase YgiN	100
2904479094	68	81.16	1	65	1	56	1.6e-04	14.6	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2904479095	230	89.47	19	226	11	197	2.1e-20	68.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904479096	406	96.71	5	403	11	392	3.9e-23	76	COG2814	Predicted arabinose efflux permease, MFS family	394
2904479097	136	96.45	1	136	2	137	1.3e-33	110.5	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2904479098	34	11.73	5	34	167	189	2.3e-03	12.3	COG0693	Putative intracellular protease/amidase	188
2904479099	72	21.25	1	67	1	68	4.9e-08	26.6	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2904479100	162	48.35	2	159	49	180	4.2e-44	145.4	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2904479101	165	23.07	1	165	521	684	1.1e-55	183.6	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2904479102	176	49.4	15	176	123	245	6.9e-08	26.8	COG1651	Protein-disulfide isomerase	244
2904479103	145	82.19	3	145	3	122	5.9e-08	28.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2904479105	171	79.89	4	170	18	168	5.8e-18	59.7	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2904479107	176	83.96	1	176	7	163	1.1e-26	88.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2904479108	300	96.68	8	300	4	294	2.9e-67	221.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904479109	343	99.7	10	341	1	330	1.9e-84	278	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2904479110	79	63.64	1	74	25	87	8.4e-13	42.5	COG1359	Quinol monooxygenase YgiN	100
2904479111	150	77.78	9	141	29	154	2.5e-07	25.9	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904479112	154	33.14	3	143	44	100	1.1e-13	46	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2904479113	271	97.74	5	266	6	264	1.7e-80	264.3	COG0300	Short-chain dehydrogenase	265
2904479114	253	88.66	1	248	1	219	1.9e-69	228.3	COG3967	Short-chain dehydrogenase involved in D-alanine esterification of teichoic acids	245
2904479115	399	97.47	2	392	9	393	1.6e-69	228.7	COG2814	Predicted arabinose efflux permease, MFS family	394
2904479116	311	95.08	1	311	9	317	2.8e-93	306.9	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2904479117	302	79.55	170	302	21	125	8.3e-24	78	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904479118	177	83.87	3	172	23	178	1.5e-18	61.9	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2904479120	121	22.67	3	120	43	81	4.8e-13	43.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2904479122	1034	99.7	1	1024	3	1013	0.0e+00	1120.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2904479123	293	33.78	10	220	4	203	4.0e-03	9.4	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2904479125	233	98.28	5	233	3	230	1.6e-64	211.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904479126	357	84.52	5	356	56	388	1.4e-38	127.8	COG0642	Signal transduction histidine kinase	336
2904479129	232	92.95	1	232	10	233	1.4e-64	212.2	COG2186	DNA-binding transcriptional regulator, FadR family	241
2904479130	298	96.73	1	298	6	301	5.4e-91	299.2	COG3734	2-keto-3-deoxy-galactonokinase	306
2904479131	205	95.26	1	205	8	208	2.0e-65	214.5	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
2904479132	382	90.88	1	365	30	368	4.4e-111	365.6	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2904479133	397	44.65	1	180	31	201	3.5e-23	69.4	COG0477	MFS family permease	338
2904479133	397	50.13	190	395	3	194	3.5e-23	13.2	COG0477	MFS family permease	338
2904479134	316	99.08	5	316	2	325	1.1e-93	307.9	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2904479135	88	89.89	4	88	1	80	1.1e-14	48.4	COG1264	Phosphotransferase system IIB components	88
2904479136	311	96.01	5	308	6	294	1.2e-41	137.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904479137	421	93.68	1	420	27	441	2.1e-59	196.5	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2904479138	326	96.98	24	326	7	295	6.1e-98	322.2	COG1175	ABC-type sugar transport system, permease component	295
2904479139	281	99.29	2	280	3	283	4.8e-80	263.3	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2904479140	453	98.42	1	453	3	437	2.9e-82	266.4	COG1486	Alpha-galactosidase/6-phospho-beta-glucosidase, family 4 of glycosyl hydrolase	442
2904479141	369	99.71	1	357	1	349	0.0e+00	468.4	COG3839	ABC-type sugar transport system, ATPase component	338
2904479142	551	97.68	13	520	1	505	0.0e+00	524.2	COG0366	Glycosidase	505
2904479143	552	96.32	8	528	1	498	0.0e+00	508.9	COG0366	Glycosidase	505
2904479145	290	97.52	4	286	4	278	1.1e-31	104.1	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2904479146	193	85.78	2	185	30	210	3.2e-65	214	COG2173	D-alanyl-D-alanine dipeptidase	211
2904479147	526	96.02	7	526	17	571	2.7e-114	377.5	COG0747	ABC-type transport system, periplasmic component	556
2904479148	338	98.43	3	338	4	316	2.2e-120	396.1	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904479149	303	94.97	14	303	15	297	1.1e-97	321	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904479150	342	99.38	9	327	1	323	2.0e-122	402.6	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2904479151	318	94.69	3	316	3	305	1.7e-100	330.8	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2904479152	294	96.85	5	283	1	277	4.4e-31	102.4	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2904479153	374	99.21	1	361	1	375	0.0e+00	460.5	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
2904479154	241	94.81	11	222	9	209	1.8e-64	211.4	COG0684	Regulator of RNase E activity RraA	210
2904479155	248	97.15	1	248	5	243	6.6e-56	184.2	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
2904479156	409	31.56	8	108	2	96	4.1e-76	103.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904479156	409	97.34	109	406	2	294	4.1e-76	152.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904479157	370	62.59	10	368	136	391	7.8e-26	86.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904479158	417	91.61	1	407	8	400	1.6e-13	43.8	COG3307	O-antigen ligase	424
2904479159	146	96.58	3	146	2	142	3.4e-62	202.8	COG0757	3-dehydroquinate dehydratase	146
2904479160	277	98.21	1	275	5	279	2.7e-40	133	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2904479162	459	51.96	247	452	4	202	1.1e-40	37.2	COG0477	MFS family permease	338
2904479162	459	54.57	20	254	6	214	1.1e-40	103.1	COG0477	MFS family permease	338
2904479163	279	97.79	1	271	1	265	3.8e-71	234	COG0253	Diaminopimelate epimerase	272
2904479164	189	92.51	7	188	7	179	1.5e-33	110.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2904479165	309	94.84	1	308	8	301	9.3e-51	167.1	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2904479166	288	93.29	3	288	17	294	2.0e-96	316.8	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904479167	306	99.06	1	306	1	315	6.8e-114	374.9	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904479168	514	95.67	1	512	10	562	4.2e-107	353.7	COG0747	ABC-type transport system, periplasmic component	556
2904479169	379	96.45	68	374	3	301	4.2e-53	174.7	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2904479170	477	99.19	1	470	1	491	0.0e+00	463.6	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
2904479171	610	99.46	9	570	3	551	0.0e+00	743.7	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2904479173	529	99.81	6	529	2	515	0.0e+00	811.2	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
2904479174	429	99.77	1	428	1	428	0.0e+00	614.2	COG0151	Phosphoribosylamine-glycine ligase	428
2904479176	90	95.74	1	90	2	91	1.1e-37	122.6	COG0776	Bacterial nucleoid DNA-binding protein	94
2904479177	196	100	1	194	1	194	1.8e-110	361.3	COG3068	Uncharacterized protein YjaG, DUF416 family	194
2904479178	226	96.24	1	214	8	212	7.6e-78	255.3	COG1515	Deoxyinosine 3'endonuclease (endonuclease V)	212
2904479179	354	98.87	1	352	4	352	0.0e+00	492.9	COG0407	Uroporphyrinogen-III decarboxylase	352
2904479180	258	92.25	2	258	18	279	1.1e-100	331.2	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
2904479181	171	94.44	1	162	1	153	4.4e-69	225.8	COG3160	Regulator of sigma D	162
2904479183	654	99.54	154	611	2	433	0.0e+00	745.2	COG0422	Thiamine biosynthesis protein ThiC	432
2904479184	217	91	2	213	15	206	1.6e-69	227.5	COG0352	Thiamine monophosphate synthase	211
2904479185	249	98.08	1	248	2	257	5.9e-80	262.5	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
2904479186	66	97.06	1	66	3	68	4.0e-18	59.9	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
2904479187	259	96.95	1	255	7	260	4.0e-122	400.8	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
2904479188	392	94.65	19	375	10	363	7.0e-88	289.1	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
2904479189	1406	40.69	894	1375	416	745	0.0e+00	32.9	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2904479189	1406	99.51	11	853	3	809	0.0e+00	1011.6	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2904479190	1342	99.54	1	1342	3	1083	0.0e+00	1544.4	COG0085	DNA-directed RNA polymerase, beta subunit/140 kD subunit	1060
2904479192	121	100	1	121	1	125	2.1e-47	155.1	COG0222	Ribosomal protein L7/L12	124
2904479193	165	92.61	1	165	1	163	2.0e-55	181.5	COG0244	Ribosomal protein L10	175
2904479194	234	99.57	1	227	1	229	1.4e-98	323.4	COG0081	Ribosomal protein L1	228
2904479195	142	99.29	2	142	1	140	1.4e-65	214.1	COG0080	Ribosomal protein L11	141
2904479196	181	98.36	5	181	2	181	5.9e-69	225.9	COG0250	Transcription antitermination factor NusG	178
2904479197	127	94.52	49	121	5	73	9.0e-27	87.1	COG0690	Preprotein translocase subunit SecE	73
2904479198	394	99.75	1	394	1	393	0.0e+00	764	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2904479203	178	75.31	17	167	31	152	7.8e-08	27.5	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904479204	316	98.94	7	292	4	282	8.9e-121	396.5	COG1072	Panthothenate kinase	283
2904479205	319	97.47	1	79	1	77	5.1e-28	89.4	COG1654	Biotin operon repressor	79
2904479205	319	98.74	84	319	2	237	4.0e-75	246.9	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
2904479206	350	97.62	6	342	6	292	3.1e-101	332.4	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
2904479207	84	12.5	2	84	16	92	2.4e-15	50.5	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
2904479208	277	70.29	14	261	83	276	2.5e-26	82.5	COG3031	Type II secretory pathway, component PulC	275
2904479209	506	48.91	32	251	136	269	5.8e-12	38.3	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
2904479211	103	98.08	1	103	1	102	2.1e-48	156	COG0051	Ribosomal protein S10	104
2904479212	209	97.36	1	209	1	221	3.0e-81	265.7	COG0087	Ribosomal protein L3	218
2904479213	201	96.31	1	201	5	213	7.7e-75	244.2	COG0088	Ribosomal protein L4	214
2904479214	100	96.81	7	99	2	92	4.1e-36	116.8	COG0089	Ribosomal protein L23	94
2904479215	274	99.64	1	273	1	274	0.0e+00	432	COG0090	Ribosomal protein L2	275
2904479216	92	98.92	1	92	1	92	1.9e-44	142.8	COG0185	Ribosomal protein S19	93
2904479217	110	91.28	1	110	10	145	1.1e-45	148.5	COG0091	Ribosomal protein L22	120
2904479218	232	93.99	12	232	1	219	9.7e-101	329.1	COG0092	Ribosomal protein S3	233
2904479219	111	74.5	1	111	30	140	4.7e-51	165.7	COG0197	Ribosomal protein L16/L10AE	146
2904479220	63	94.12	1	63	1	64	7.9e-28	89.6	COG0255	Ribosomal protein L29	69
2904479221	84	93.1	1	83	5	85	3.7e-40	129.1	COG0186	Ribosomal protein S17	87
2904479222	123	100	1	123	1	123	1.5e-59	192.7	COG0093	Ribosomal protein L14	122
2904479223	104	97.22	1	104	2	106	9.4e-31	99.7	COG0198	Ribosomal protein L24	104
2904479224	179	99.44	1	179	1	179	3.0e-84	274.4	COG0094	Ribosomal protein L5	180
2904479225	101	100	41	101	1	61	2.0e-29	94.1	COG0199	Ribosomal protein S14	61
2904479226	130	99.25	1	130	1	132	7.2e-53	171.3	COG0096	Ribosomal protein S8	132
2904479227	177	98.88	1	177	1	177	2.7e-69	225.6	COG0097	Ribosomal protein L6P/L9E	178
2904479228	117	96.03	1	117	6	126	4.4e-44	143.3	COG0256	Ribosomal protein L18	125
2904479229	166	88.59	1	166	20	182	4.9e-72	234.4	COG0098	Ribosomal protein S5	181
2904479230	59	100	5	59	1	55	6.6e-29	92.7	COG1841	Ribosomal protein L30/L7E	55
2904479231	144	98.05	1	144	1	151	1.2e-45	148.7	COG0200	Ribosomal protein L15	152
2904479232	443	97.73	1	437	6	435	0.0e+00	556.7	COG0201	Preprotein translocase subunit SecY	436
2904479233	38	100	1	38	1	38	1.3e-24	79.4	COG0257	Ribosomal protein L36	38
2904479235	118	97.52	1	118	1	118	5.4e-52	168.5	COG0099	Ribosomal protein S13	121
2904479236	129	99.23	1	129	2	130	5.7e-63	204.3	COG0100	Ribosomal protein S11	129
2904479237	206	100	1	206	1	210	1.3e-68	224.1	COG0522	Ribosomal protein S4 or related protein	205
2904479238	329	99.69	8	328	1	318	1.5e-128	421.6	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
2904479239	129	100	1	116	1	116	2.7e-56	182	COG0203	Ribosomal protein L17	116
2904479241	138	96.97	2	121	1	128	6.8e-34	110.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
2904479242	66	81.82	1	63	1	54	3.5e-24	76.7	COG3036	Stalled ribosome alternative rescue factor ArfA	66
2904479243	138	100	1	133	1	131	7.6e-54	174.9	COG1970	Large-conductance mechanosensitive channel	130
2904479244	458	98.66	233	455	1	221	1.3e-118	133	COG0569	Trk K+ transport system, NAD-binding component	225
2904479244	458	99.55	1	230	1	223	1.3e-118	259	COG0569	Trk K+ transport system, NAD-binding component	225
2904479245	364	99.44	28	364	1	356	4.3e-109	358.4	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
2904479246	311	98.05	1	308	2	303	3.3e-130	427.1	COG0223	Methionyl-tRNA formyltransferase	307
2904479247	170	99.41	1	164	1	168	7.3e-66	214	COG0242	Peptide deformylase	168
2904479248	389	98.05	1	377	7	358	1.3e-109	359.7	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
2904479249	157	100	1	157	1	157	2.3e-77	251.5	COG2922	Uncharacterized conserved protein Smg, DUF494 family	157
2904479250	186	28.48	1	57	18	62	4.0e-48	41.2	COG0551	ssDNA-binding Zn-finger and Zn-ribbon domains of topoisomerase 1	140
2904479250	186	85.44	50	182	22	156	4.0e-48	118.3	COG0551	ssDNA-binding Zn-finger and Zn-ribbon domains of topoisomerase 1	140
2904479251	189	88.21	1	189	12	198	2.2e-58	190.1	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
2904479252	275	97.18	1	275	6	281	6.9e-90	294.2	COG0169	Shikimate 5-dehydrogenase	283
2904479253	180	95.48	2	180	3	171	1.0e-65	213.7	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2904479256	235	98.67	1	232	1	223	1.2e-62	204.3	COG2135	Putative SOS response-associated peptidase YedK	226
2904479257	150	14.74	26	58	131	158	1.2e-22	16	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2904479257	150	17.37	7	45	72	104	1.2e-22	7.3	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2904479257	150	49.47	56	149	83	176	1.2e-22	57	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2904479258	510	79.15	1	359	11	363	4.1e-43	136.6	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2904479259	89	93.94	1	88	5	97	3.2e-20	65.7	COG4095	Uncharacterized conserved protein, contains PQ loop repeat	89
2904479260	338	94.3	1	338	6	336	3.4e-39	128.5	COG0673	Predicted dehydrogenase	342
2904479261	277	97.06	19	277	5	268	2.9e-26	85.7	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
2904479262	411	96	45	411	13	372	1.8e-81	267.3	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2904479263	264	77.27	140	264	22	123	5.9e-21	67.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904479264	396	97.47	1	394	7	392	2.0e-123	405.4	COG2807	Cyanate permease	395
2904479265	305	98.01	2	300	3	297	1.2e-72	238.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904479266	465	34.91	16	179	3	150	1.7e-65	85.3	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2904479266	465	43.87	221	439	234	419	1.7e-65	130.7	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2904479267	155	93.38	1	149	5	145	3.4e-34	111.1	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
2904479268	283	88.35	3	281	23	295	2.2e-51	167.9	COG3386	Sugar lactone lactonase YvrE	307
2904479269	476	97.55	107	432	1	318	2.0e-97	319.2	COG4644	Transposase and inactivated derivatives, TnpA family	323
2904479271	260	59.4	5	247	120	318	7.3e-27	87.9	COG0582	Integrase	309
2904479272	210	91.74	6	209	9	219	1.0e-19	64.2	COG1266	Membrane protease YdiL, CAAX protease family	226
2904479274	424	80.11	9	357	18	299	2.6e-21	67.5	COG1566	Multidrug resistance efflux pump	352
2904479275	699	95.92	19	699	2	683	0.0e+00	682.2	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2904479276	528	93.99	315	517	10	181	4.8e-45	146.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904479280	344	99.08	6	329	3	325	1.3e-65	215.1	COG3547	Transposase	303
2904479281	276	92.25	4	265	17	278	9.1e-45	146.3	COG2801	Transposase InsO and inactivated derivatives	232
2904479283	87	76.92	1	85	7	96	5.7e-08	20.7	COG2963	Transposase and inactivated derivatives	116
