gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
651495799	188	50.27	2	185	1	178	3.0e-56	211	COG0241	Histidinol phosphatase or a related phosphatase	181
651495800	345	62.21	1	343	1	339	0.0e+00	469	COG1135	ABC-type methionine transport system, ATPase component	339
651495801	230	53.6	9	230	2	222	2.0e-67	248	COG2011	ABC-type methionine transport system, permease component	222
651495802	276	48.74	1	276	1	268	3.0e-81	294	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
651495806	1416	50.52	15	854	2	808	0.0e+00	906	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
651495808	123	70.97	1	123	1	124	3.0e-22	97.2	COG0222	Ribosomal protein L7/L12	124
651495809	163	51.22	1	160	1	163	2.0e-38	151	COG0244	Ribosomal protein L10	175
651495810	129	53.08	1	129	3	129	6.0e-35	139	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
651495811	248	47.43	1	248	1	248	2.0e-74	272	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
651495812	227	49.25	24	222	1	176	1.0e-45	176	COG3477	Uncharacterized membrane protein YagU, involved in acid resistance, DUF1440 family	176
651495813	317	40.32	5	315	1	239	1.0e-66	246	COG0176	Transaldolase	239
651495814	541	37.48	4	540	9	562	2.0e-121	429	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
651495815	306	47.78	1	306	1	315	5.0e-84	304	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
651495816	311	43.36	27	311	3	287	2.0e-73	269	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
651495817	323	57.05	4	318	1	316	1.0e-127	449	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
651495818	332	49.84	7	317	1	260	2.0e-98	352	COG4608	ABC-type oligopeptide transport system, ATPase component	309
651495819	289	39.93	1	289	4	300	1.0e-79	290	COG2990	Uncharacterized protein VirK/YbjX	300
651495820	209	57.5	10	208	1	200	1.0e-73	269	COG0218	GTP-binding protein EngB required for normal cell division	200
651495821	509	58.91	15	502	1	490	0.0e+00	653	COG0606	Predicted ATPase with chaperone activity	490
651495822	194	48.94	100	192	1	93	7.0e-27	113	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
651495823	180	43.26	3	180	55	223	1.0e-43	169	COG1040	Predicted amidophosphoribosyltransferases	225
651495829	870	54.32	1	602	2	611	0.0e+00	856	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
651495830	437	19.24	44	436	43	393	3.0e-05	43.7	COG2814	Predicted arabinose efflux permease, MFS family	394
651495831	225	41.74	3	220	1	205	1.0e-54	206	COG0352	Thiamine monophosphate synthase	211
651495832	269	54.85	2	268	1	263	8.0e-100	356	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
651495833	264	51.52	1	264	2	265	1.0e-89	322	COG2145	Hydroxyethylthiazole kinase, sugar kinase family	265
651495834	216	43.06	1	215	2	217	1.0e-62	232	COG0819	Thiaminase	218
651495835	314	30.72	1	309	6	319	7.0e-42	164	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
651495836	245	38.93	1	242	8	251	5.0e-46	178	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
651495837	241	40.08	1	241	3	246	6.0e-61	227	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
651495838	281	65	2	281	1	279	4.0e-125	440	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
651495839	138	54.4	12	135	10	134	2.0e-27	114	COG3223	Phosphate starvation-inducible membrane PsiE (function unknown)	138
651495840	629	49.86	272	628	1	342	3.0e-96	346	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
651495841	628	41.86	39	622	2	568	0.0e+00	494	COG0358	DNA primase (bacterial type)	568
651495842	71	59.7	1	67	1	67	1.0e-07	48	COG0828	Ribosomal protein S21	67
651495843	342	58.6	1	342	1	340	0.0e+00	480	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
651495845	193	48.7	1	192	3	195	9.0e-75	272	COG1435	Thymidine kinase	201
651495846	406	35.85	1	401	6	415	2.0e-59	223	COG0814	Amino acid permease	415
651495847	128	41.41	1	128	1	127	4.0e-23	100	COG3111	Predicted periplasmic protein YdeI with OB-fold, BOF family	128
651495849	675	59.52	9	675	5	666	0.0e+00	974	COG0272	NAD-dependent DNA ligase	667
651495850	344	35.47	1	343	2	316	2.0e-71	262	COG3115	Cell division protein ZipA, interacts with FtsZ	324
651495851	282	54.1	5	248	2	245	9.0e-79	287	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
651495852	316	55.66	3	308	1	300	2.0e-104	372	COG0031	Cysteine synthase	300
651495853	257	39.78	1	257	1	269	9.0e-39	154	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
651495854	238	43.18	19	237	7	221	3.0e-53	201	COG0765	ABC-type amino acid transport system, permease component	222
651495855	256	60.33	1	242	2	236	2.0e-101	361	COG1126	ABC-type polar amino acid transport system, ATPase component	240
651495856	247	44.53	1	246	5	238	1.0e-50	193	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
651495857	503	69.8	1	500	1	499	0.0e+00	852	COG0554	Glycerol kinase	499
651495867	772	62.1	1	770	3	780	0.0e+00	1050	COG2183	Transcriptional accessory protein Tex/SPT6	780
651495868	158	42.76	7	157	1	151	2.0e-38	151	COG0782	Transcription elongation factor, GreA/GreB family	151
651495870	238	71.49	1	235	2	236	9.0e-111	393	COG0813	Purine-nucleoside phosphorylase	236
651495871	415	63.33	1	408	1	403	0.0e+00	473	COG1972	Nucleoside permease NupC	404
651495872	262	26.72	11	255	21	242	1.0e-35	143	COG1180	Pyruvate-formate lyase-activating enzyme	260
651495873	119	49.48	22	118	1	97	5.0e-29	119	COG3691	Uncharacterized conserved protein YfcZ, UPF0381/DUF406 family	98
651495874	334	55.66	1	312	3	314	3.0e-117	414	COG0180	Tryptophanyl-tRNA synthetase	314
651495875	207	51.46	1	203	1	204	2.0e-59	222	COG2915	Regulator of phage lambda lysogenization HflD, binds to CII and stimulates its degradation	207
651495876	455	33.99	12	455	1	435	1.0e-117	416	COG0015	Adenylosuccinate lyase	438
651495877	137	30.08	2	134	8	140	1.0e-17	82.2	COG4125	Uncharacterized membrane protein	149
651495878	384	46.72	45	383	14	361	1.0e-86	313	COG0687	Spermidine/putrescine-binding periplasmic protein	363
651495879	431	28.72	30	412	2	387	6.0e-66	245	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
651495880	150	35.1	1	150	3	153	4.0e-28	117	COG1522	DNA-binding transcriptional regulator, Lrp family	154
651495881	330	74.55	1	330	1	330	0.0e+00	585	COG2502	Asparagine synthetase A	330
651495882	387	24.58	207	384	56	222	1.0e-16	81	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
651495883	425	31.31	23	422	4	385	3.0e-66	245	COG0247	Fe-S oxidoreductase	388
651495884	429	52.91	1	429	1	418	0.0e+00	579	COG3075	Anaerobic glycerol-3-phosphate dehydrogenase	421
651495885	583	36.87	38	557	12	532	0.0e+00	505	COG0578	Glycerol-3-phosphate dehydrogenase	532
651495886	480	49.06	1	477	1	448	0.0e+00	545	COG2271	Sugar phosphate permease	448
651495888	361	36.75	29	360	3	257	1.0e-43	170	COG0584	Glycerophosphoryl diester phosphodiesterase	257
651495891	222	48.21	25	219	9	182	7.0e-55	207	COG3059	Uncharacterized membrane protein YkgB	182
651495892	1297	40.12	160	987	1	741	0.0e+00	803	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
651495894	715	13.27	114	712	153	778	4.0e-09	57.2	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
651495895	228	43.69	7	228	2	217	4.0e-56	211	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
651495896	223	60.81	1	222	1	220	2.0e-89	321	COG0036	Pentose-5-phosphate-3-epimerase	220
651495897	554	30.99	1	491	2	496	4.0e-72	266	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
651495898	109	45.28	1	106	1	106	1.0e-17	81.3	COG2076	Multidrug transporter EmrE and related cation transporters	106
651495899	381	51.61	10	381	7	373	9.0e-124	437	COG0641	Sulfatase maturation enzyme AslB, radical SAM superfamily	378
651495900	197	28.72	19	197	23	208	1.0e-25	109	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
651495901	481	26.01	1	466	5	473	4.0e-81	295	COG3119	Arylsulfatase A or related enzyme	475
651495902	582	49.38	13	570	2	555	0.0e+00	690	COG4146	Uncharacterized membrane permease YidK, sodium:solute symporter family	571
651495903	264	22.81	1	259	2	252	2.0e-12	66.6	COG0730	Uncharacterized membrane protein YfcA	258
651495908	173	58.48	1	166	1	170	6.0e-53	200	COG4635	Protoporphyrinogen IX oxidase, menaquinone-dependent (flavodoxin domain)	175
651495909	473	44.42	1	472	15	487	8.0e-99	354	COG0168	Trk-type K+ transport system, membrane component	499
651495910	203	41.67	1	203	1	203	6.0e-52	197	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
651495911	79	37.66	4	79	2	78	3.0e-20	89.9	COG0425	TusA-related sulfurtransferase	78
651495913	619	43.94	1	455	1	447	3.0e-125	442	COG3276	Selenocysteine-specific translation elongation factor	447
651495914	460	54.34	75	460	15	395	2.0e-116	412	COG1921	Seryl-tRNA(Sec) selenium transferase	395
651495916	700	67.76	1	700	1	693	0.0e+00	1015	COG0480	Translation elongation factor EF-G, a GTPase	697
651495917	169	64.19	15	162	1	148	2.0e-56	211	COG0049	Ribosomal protein S7	148
651495918	124	77.24	1	123	7	129	3.0e-49	187	COG0048	Ribosomal protein S12	129
651495919	461	30.7	13	453	2	443	1.0e-59	224	COG0038	H+/Cl- antiporter ClcA	443
651495920	328	35.46	1	304	1	301	3.0e-80	292	COG0042	tRNA-dihydrouridine synthase	323
651495921	215	62.31	15	213	4	201	1.0e-82	299	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
651495922	379	64.17	178	364	1	186	4.0e-81	295	COG3172	Nicotinamide riboside kinase	187
651495923	226	21.9	2	189	6	186	3.0e-04	39.1	COG2129	Predicted phosphoesterase, related to the Icc protein	226
651495927	670	46.6	1	651	1	655	0.0e+00	612	COG0210	Superfamily I DNA or RNA helicase	655
651495928	70	50	1	68	1	72	2.0e-15	74.6	COG5645	Uncharacterized conserved protein YceK	80
651495929	158	56.41	1	156	2	157	4.0e-60	223	COG0669	Phosphopantetheine adenylyltransferase	159
651495930	422	50.24	1	414	9	419	0.0e+00	508	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
651495931	252	20.61	1	249	2	257	6.0e-18	84.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
651495932	263	56.7	3	262	2	251	2.0e-81	296	COG0149	Triosephosphate isomerase	251
651495934	295	62.59	1	294	6	299	3.0e-128	451	COG4973	Site-specific recombinase XerC	299
651495935	780	43.34	3	778	4	784	0.0e+00	683	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
651495936	185	58.79	5	185	2	183	2.0e-80	291	COG2818	3-methyladenine DNA glycosylase Tag	188
651495937	272	37.68	1	269	6	279	7.0e-70	257	COG0169	Shikimate 5-dehydrogenase	283
651495938	183	37.84	3	183	16	197	3.0e-44	171	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
651495939	180	40.3	48	180	7	139	2.0e-25	109	COG0551	ssDNA-binding Zn-finger and Zn-ribbon domains of topoisomerase 1	140
651495940	638	46.73	1	526	3	530	0.0e+00	561	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
651495941	345	23.6	8	328	2	316	5.0e-40	158	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
651495942	105	33.03	1	105	2	110	8.0e-19	85.4	COG0607	Rhodanese-related sulfurtransferase	110
651495943	295	36.64	1	289	5	292	2.0e-62	233	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
651495944	292	31.16	1	291	1	287	1.0e-39	157	COG0583	DNA-binding transcriptional regulator, LysR family	297
651495945	493	38.62	19	363	1	338	3.0e-119	422	COG0059	Ketol-acid reductoisomerase	338
651495946	230	41.79	35	227	62	248	2.0e-51	195	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
651495948	227	66.08	1	227	2	228	2.0e-102	364	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
651495949	410	43.9	6	410	10	419	1.0e-90	326	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
651495950	280	47.79	28	252	29	250	2.0e-72	265	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
651495951	209	44.17	5	206	1	206	7.0e-50	190	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
651495952	834	49.4	1	829	1	832	0.0e+00	1096	COG3072	Adenylate cyclase	853
651495953	310	61.44	5	309	2	307	5.0e-120	424	COG0181	Porphobilinogen deaminase	307
651495954	253	30.2	1	245	2	242	6.0e-39	154	COG1587	Uroporphyrinogen-III synthase	248
651495955	432	43.78	15	411	3	391	1.0e-84	307	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
651495956	428	45.02	1	402	1	393	5.0e-118	418	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
651495957	219	40.78	11	215	16	221	4.0e-47	181	COG0765	ABC-type amino acid transport system, permease component	222
651495958	222	34.26	5	220	8	218	9.0e-44	170	COG0765	ABC-type amino acid transport system, permease component	222
651495959	254	58.4	2	239	1	237	5.0e-104	370	COG1126	ABC-type polar amino acid transport system, ATPase component	240
651495960	285	36.36	5	269	2	265	4.0e-32	132	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
651495967	162	31.13	9	159	8	153	7.0e-25	106	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
651495969	95	36.73	1	95	1	96	3.0e-18	83.4	COG2168	Sulfur transfer complex TusBCD TusB component, DsrH family	96
651495970	119	56.3	1	119	2	118	6.0e-34	136	COG2923	Sulfur relay (sulfurtransferase) complex TusC component, DsrF/TusC family	118
651495971	126	46.83	1	126	1	126	8.0e-39	152	COG1553	Sulfur relay (sulfurtransferase) complex TusBCD TusD component, DsrE family	126
651495972	221	64.09	7	221	1	220	1.0e-76	279	COG2964	Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains	220
651495973	240	44.5	29	237	3	205	5.0e-51	194	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
651495974	73	62.5	2	73	1	72	2.0e-14	70.7	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
651495975	370	43.66	14	367	2	351	3.0e-107	381	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
651495976	289	22.54	4	286	5	286	3.0e-34	139	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
651495977	283	30.8	10	272	3	260	2.0e-41	162	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
651495978	363	25.6	12	331	5	333	2.0e-51	196	COG4134	ABC-type uncharacterized transport system YnjBCD, periplasmic component	384
651495979	461	27.45	12	461	4	457	4.0e-48	185	COG0471	Di- and tricarboxylate transporter	461
651495981	408	18.02	13	404	9	393	2.0e-18	86.8	COG2814	Predicted arabinose efflux permease, MFS family	394
651495982	240	28.63	5	236	3	235	1.0e-36	147	COG2186	DNA-binding transcriptional regulator, FadR family	241
651495983	358	26.39	7	357	4	341	1.0e-50	194	COG0673	Predicted dehydrogenase	342
651495984	368	25.54	1	364	3	342	7.0e-49	188	COG0673	Predicted dehydrogenase	342
651495987	210	55.45	2	210	4	214	7.0e-80	290	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
651495988	558	37.67	9	558	1	555	3.0e-101	362	COG0747	ABC-type transport system, periplasmic component	556
651495990	169	46.91	4	161	1	159	3.0e-45	174	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
651495991	314	46.52	1	312	1	316	4.0e-108	384	COG3026	Negative regulator of sigma E activity	320
651495992	193	45.13	1	191	5	199	5.0e-48	184	COG3073	Negative regulator of sigma E activity	213
651495993	191	36.36	6	191	1	181	7.0e-33	133	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
651495994	85	41.46	1	82	10	91	4.0e-21	92.6	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
651495995	563	58.88	231	563	1	337	2.0e-98	353	COG1299	Phosphotransferase system, fructose-specific IIC component	343
651495996	314	46.62	4	313	1	310	1.0e-94	339	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
651495997	506	57.75	2	143	1	142	1.0e-47	184	COG4668	Mannitol/fructose-specific phosphotransferase system, IIA domain	142
651495999	436	34.94	1	430	1	426	3.0e-96	345	COG1253	Hemolysin or related protein, contains CBS domains	429
651496001	260	51.54	1	257	1	256	9.0e-81	293	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
651496003	210	45.41	1	205	1	205	6.0e-58	217	COG0125	Thymidylate kinase	208
651496004	349	44.9	1	343	9	342	2.0e-112	399	COG1559	Cell division protein YceG, involved in septum cleavage	342
651496005	310	23.46	1	310	1	315	8.0e-19	88.2	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
651496006	195	55.93	17	193	2	176	2.0e-64	238	COG2065	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	179
651496007	1159	50.91	5	1157	2	1139	0.0e+00	1381	COG0587	DNA polymerase III, alpha subunit	1139
651496008	152	19.14	1	140	14	175	1.0e-22	99.2	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
651496009	482	34.31	6	482	1	412	1.0e-95	344	COG2195	Di- or tripeptidase	414
651496010	282	32.52	2	282	22	296	8.0e-44	170	COG0501	Zn-dependent protease with chaperone function	302
651496011	188	46.77	4	188	4	186	7.0e-49	186	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
651496012	88	72.73	1	88	1	88	3.0e-36	143	COG3084	Uncharacterized protein YihD, DUF1040 family	88
651496014	113	63.96	3	113	1	110	1.0e-41	161	COG3085	Uncharacterized conserved protein YifE, UPF0438 family	112
651496015	363	32.34	2	356	79	432	6.0e-84	304	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
651496017	146	52.05	1	146	1	143	1.0e-46	178	COG3086	Positive regulator of sigma E activity	150
651496018	439	29.2	1	438	7	456	9.0e-32	131	COG0531	Amino acid transporter	466
651496019	720	45.89	99	718	1	557	0.0e+00	685	COG1982	Arginine/lysine/ornithine decarboxylase	557
651496021	342	53.01	10	341	1	309	3.0e-128	451	COG0078	Ornithine carbamoyltransferase	310
651496022	657	38.18	7	574	1	517	2.0e-122	433	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
651496023	504	39.25	6	458	3	439	9.0e-109	387	COG0733	Na+-dependent transporter, SNF family	439
651496024	212	40.27	1	212	1	220	1.0e-35	143	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
651496025	551	48.36	1	547	2	549	0.0e+00	614	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
651496026	81	49.32	10	80	1	73	4.0e-13	66.5	COG3978	Acetolactate synthase small subunit, contains ACT domain	86
651496029	612	53.75	1	611	8	575	0.0e+00	806	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
651496030	513	53.76	10	352	3	347	2.0e-125	442	COG1171	Threonine dehydratase	347
651496031	142	51.11	1	134	1	135	2.0e-34	138	COG0355	FoF1-type ATP synthase, epsilon subunit	135
651496032	457	76.56	1	457	1	465	0.0e+00	836	COG0055	FoF1-type ATP synthase, beta subunit	468
651496033	289	52.45	5	289	1	286	5.0e-102	364	COG0224	FoF1-type ATP synthase, gamma subunit	287
651496034	513	66.67	1	513	1	502	0.0e+00	833	COG0056	FoF1-type ATP synthase, alpha subunit	504
651496035	177	45.51	1	176	1	178	4.0e-43	167	COG0712	FoF1-type ATP synthase, delta subunit	178
651496036	156	46.75	3	156	5	158	2.0e-19	88.4	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
651496037	84	41.03	1	78	2	79	2.0e-05	41	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
651496038	262	44.49	5	258	8	244	2.0e-51	196	COG0356	FoF1-type ATP synthase, membrane subunit a	246
651496039	124	39.2	1	123	1	125	9.0e-18	82.6	COG3312	FoF1-type ATP synthase assembly protein I	128
651496040	203	45.97	1	203	1	211	5.0e-59	220	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
651496041	165	39.42	62	165	11	114	2.0e-23	102	COG1733	DNA-binding transcriptional regulator, HxlR family	120
651496042	283	31.88	4	268	1	275	3.0e-30	125	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
651496043	629	66.88	3	626	1	621	0.0e+00	1014	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
651496044	145	32.89	1	145	2	151	3.0e-25	107	COG0716	Flavodoxin	151
651496045	88	51.9	17	88	1	79	1.0e-10	58.2	COG3074	Cell division protein ZapB, interacts with FtsZ	79
651496046	352	67.27	16	348	1	332	0.0e+00	485	COG1494	Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase or related protein	332
651496047	860	50.81	6	858	2	843	0.0e+00	987	COG0249	DNA mismatch repair ATPase MutS	843
651496048	238	34.06	10	238	1	221	1.0e-44	173	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
651496049	453	38.11	12	451	1	433	0.0e+00	469	COG0621	tRNA A37 methylthiotransferase MiaB	437
651496051	371	32.97	1	370	1	334	5.0e-100	358	COG0136	Aspartate-semialdehyde dehydrogenase	334
651496053	311	30.23	14	309	1	291	8.0e-53	201	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
651496054	484	34.26	15	483	4	461	3.0e-53	203	COG0471	Di- and tricarboxylate transporter	461
651496063	458	56.62	1	458	5	470	0.0e+00	687	COG3033	Tryptophanase	471
651496064	404	36.43	1	399	8	415	2.0e-51	196	COG0814	Amino acid permease	415
651496065	225	31.72	1	223	6	217	1.0e-40	159	COG2964	Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains	220
651496076	393	70.05	1	393	1	394	0.0e+00	636	COG0027	Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	394
651496077	167	66.05	1	162	1	161	3.0e-72	264	COG1854	S-ribosylhomocysteine lyase LuxS, autoinducer biosynthesis	161
651496078	159	33.54	1	157	1	156	2.0e-20	91.5	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
651496079	199	29.1	9	195	1	189	1.0e-39	156	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
651496081	514	43.75	18	507	1	492	0.0e+00	465	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
651496082	1299	36.44	14	1299	1	1278	0.0e+00	975	COG2911	Autotransporter translocation and assembly factor TamB	1278
651496083	578	40.85	1	578	6	594	0.0e+00	526	COG0729	Outer membrane translocation and assembly module TamA	594
651496084	144	61.38	1	144	1	145	5.0e-59	219	COG1490	D-Tyr-tRNAtyr deacylase	145
651496085	274	28.89	6	263	19	288	5.0e-35	141	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
651496086	157	49.67	6	155	2	151	3.0e-56	210	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
651496087	221	40.28	4	217	1	210	1.0e-51	196	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
651496088	499	26.64	19	496	6	520	4.0e-37	149	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
651496089	266	61.11	14	265	2	248	2.0e-97	348	COG2820	Uridine phosphorylase	248
651496090	271	36.62	1	269	1	282	2.0e-71	262	COG0169	Shikimate 5-dehydrogenase	283
651496092	265	55.14	72	256	2	186	4.0e-70	257	COG1045	Serine acetyltransferase	194
651496093	335	51.96	5	335	1	329	4.0e-126	444	COG0240	Glycerol-3-phosphate dehydrogenase	329
651496094	169	49.69	6	166	1	157	3.0e-50	191	COG1952	Preprotein translocase subunit SecB	157
651496095	148	34.86	38	146	1	109	3.0e-20	91.1	COG0607	Rhodanese-related sulfurtransferase	110
651496096	349	44.38	11	348	5	348	1.0e-94	339	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
651496097	433	58.81	1	433	1	436	0.0e+00	493	COG2704	Anaerobic C4-dicarboxylate transporter	436
651496099	507	45.24	5	504	7	481	0.0e+00	499	COG1288	Uncharacterized membrane protein YfcC, ion transporter superfamily	481
651496100	411	20.52	55	399	58	377	1.0e-06	47.9	COG2814	Predicted arabinose efflux permease, MFS family	394
651496101	599	33.57	45	595	15	567	2.0e-101	364	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
651496102	574	33.15	15	568	15	567	1.0e-97	350	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
651496103	672	15.94	10	672	44	768	8.0e-31	129	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
651496104	197	18.99	18	196	19	197	3.0e-08	52	COG1309	DNA-binding transcriptional regulator, AcrR family	201
651496105	296	36.18	1	289	5	295	4.0e-77	281	COG2990	Uncharacterized protein VirK/YbjX	300
651496106	805	67.98	2	782	1	782	0.0e+00	1217	COG0466	ATP-dependent Lon protease, bacterial type	782
651496107	382	43.7	1	379	29	409	4.0e-116	411	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
651496108	219	57.71	1	219	1	226	2.0e-76	278	COG0120	Ribose 5-phosphate isomerase	227
651496109	419	43.5	18	345	1	323	2.0e-89	323	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
651496111	159	36.54	1	154	2	157	1.0e-28	119	COG0680	Ni,Fe-hydrogenase maturation factor	160
651496112	569	53.35	4	569	1	545	0.0e+00	655	COG0374	Ni,Fe-hydrogenase I large subunit	545
651496113	408	46.82	3	384	4	390	9.0e-77	281	COG5557	Ni/Fe-hydrogenase 2 integral membrane subunit HybB	401
651496114	345	29.63	36	251	11	203	1.0e-38	154	COG0437	Fe-S-cluster-containing dehydrogenase component	203
651496115	382	50.56	14	370	13	354	8.0e-114	403	COG1740	Ni,Fe-hydrogenase I small subunit	355
651496116	379	40.37	1	377	73	448	1.0e-89	323	COG2271	Sugar phosphate permease	448
651496117	808	66.97	7	557	2	552	0.0e+00	927	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
651496118	776	20.16	39	776	51	768	4.0e-43	170	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
651496119	593	40.68	29	583	1	557	0.0e+00	607	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
651496120	552	32.47	11	551	2	541	7.0e-94	338	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
651496121	311	60.49	5	290	1	283	2.0e-104	372	COG1072	Panthothenate kinase	283
651496126	272	34.69	5	272	2	264	1.0e-46	180	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
651496127	131	38.4	1	124	1	125	6.0e-17	79.8	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
651496128	170	39.16	25	166	22	163	3.0e-32	131	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
651496129	351	62.72	1	283	1	279	7.0e-87	314	COG0468	RecA/RadA recombinase	279
651496130	280	44.96	4	280	13	290	4.0e-88	317	COG4667	Predicted phospholipase, patatin/cPLA2 family	292
651496131	222	29.17	9	128	5	121	5.0e-15	74.6	COG3070	Transcriptional regulator of competence genes, TfoX/Sxy family	121
651496133	175	57.74	7	170	1	168	2.0e-56	211	COG0242	Peptide deformylase	168
651496134	318	50.98	3	307	1	301	8.0e-117	413	COG0223	Methionyl-tRNA formyltransferase	307
651496135	445	39.72	102	444	1	355	1.0e-89	323	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
651496137	458	37.07	1	230	1	225	2.0e-46	180	COG0569	Trk K+ transport system, NAD-binding component	225
651496138	128	59.26	1	128	1	130	2.0e-37	147	COG1970	Large-conductance mechanosensitive channel	130
651496139	158	69.43	2	158	1	157	2.0e-67	248	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
651496140	227	47.37	1	224	1	228	1.0e-72	265	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
651496141	92	46.67	1	90	24	113	2.0e-18	84.2	COG2919	Cell division protein FtsB	117
651496142	272	57.09	1	272	1	274	5.0e-91	327	COG2503	Predicted secreted acid phosphatase	274
651496143	207	21.83	1	195	2	197	1.0e-07	50	COG1309	DNA-binding transcriptional regulator, AcrR family	201
651496144	301	30.64	1	295	1	293	5.0e-42	165	COG0583	DNA-binding transcriptional regulator, LysR family	297
651496145	241	68.26	1	162	1	165	3.0e-70	258	COG0678	Peroxiredoxin	165
651496147	349	54.68	9	347	1	337	3.0e-109	388	COG1085	Galactose-1-phosphate uridylyltransferase	338
651496148	239	31.02	22	237	12	220	4.0e-36	145	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
651496149	400	15.58	80	400	98	445	9.0e-04	38.6	COG2211	Na+/melibiose symporter or related transporter	467
651496150	273	20.56	1	269	4	259	1.0e-09	57	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
651496152	208	26.47	20	205	12	215	7.0e-18	84	COG0705	Membrane associated serine protease, rhomboid family	228
651496153	251	38.74	1	251	1	253	2.0e-62	232	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
651496154	158	62.58	1	154	2	155	1.0e-67	248	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
651496155	194	45.99	12	194	1	186	8.0e-61	226	COG0742	16S rRNA G966 N2-methylase RsmD	187
651496156	485	55.85	145	479	3	339	2.0e-114	406	COG0552	Signal recognition particle GTPase	340
651496157	218	59.63	1	218	1	217	6.0e-93	333	COG2884	ABC-type ATPase involved in cell division	223
651496158	310	38.08	8	309	1	297	8.0e-73	267	COG2177	Cell division protein FtsX	297
651496159	1348	24.67	826	1348	196	715	2.0e-11	65.6	COG5295	Autotransporter adhesin	715
651496160	120	74.51	18	119	1	102	9.0e-41	158	COG0051	Ribosomal protein S10	104
651496161	208	64.15	1	208	1	212	1.0e-76	279	COG0087	Ribosomal protein L3	218
651496162	200	46.19	1	200	2	211	9.0e-55	206	COG0088	Ribosomal protein L4	214
651496163	99	53.19	6	98	1	94	4.0e-23	99.5	COG0089	Ribosomal protein L23	94
651496164	273	66.18	1	273	1	275	1.0e-111	396	COG0090	Ribosomal protein L2	275
651496165	91	71.43	1	91	1	91	3.0e-37	146	COG0185	Ribosomal protein S19	93
651496166	110	70.91	1	110	9	118	5.0e-35	139	COG0091	Ribosomal protein L22	120
651496167	235	63.44	12	235	1	227	6.0e-80	290	COG0092	Ribosomal protein S3	233
651496168	136	62.5	1	133	2	137	2.0e-46	178	COG0197	Ribosomal protein L16/L10AE	146
651496169	63	56.45	2	63	4	65	3.0e-10	56.8	COG0255	Ribosomal protein L29	69
651496170	85	58.33	1	84	4	87	1.0e-22	97.6	COG0186	Ribosomal protein S17	87
651496171	123	75.61	1	123	1	122	2.0e-49	187	COG0093	Ribosomal protein L14	122
651496172	103	54.29	1	103	1	103	1.0e-19	88.4	COG0198	Ribosomal protein L24	104
651496173	179	65.92	1	179	1	179	8.0e-79	286	COG0094	Ribosomal protein L5	180
651496174	101	65.57	41	101	1	61	1.0e-17	81.8	COG0199	Ribosomal protein S14	61
651496175	130	56.49	1	129	1	131	4.0e-45	173	COG0096	Ribosomal protein S8	132
651496176	177	55.37	1	176	1	176	2.0e-60	225	COG0097	Ribosomal protein L6P/L9E	178
651496177	117	51.67	1	117	6	125	1.0e-28	118	COG0256	Ribosomal protein L18	125
651496178	166	59.28	1	166	14	180	1.0e-57	215	COG0098	Ribosomal protein S5	181
651496179	59	58.18	5	59	1	55	3.0e-13	66.7	COG1841	Ribosomal protein L30/L7E	55
651496180	144	56	1	144	1	150	8.0e-33	132	COG0200	Ribosomal protein L15	152
651496181	441	50	1	432	1	432	6.0e-128	451	COG0201	Preprotein translocase subunit SecY	436
651496182	37	73.68	1	37	1	38	3.0e-04	36.7	COG0257	Ribosomal protein L36	38
651496183	129	70.54	1	129	1	129	2.0e-50	190	COG0100	Ribosomal protein S11	129
651496184	206	63.94	1	206	1	205	9.0e-61	226	COG0522	Ribosomal protein S4 or related protein	205
651496185	329	59.12	8	323	1	313	2.0e-99	355	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
651496186	127	72.41	1	116	1	116	2.0e-46	177	COG0203	Ribosomal protein L17	116
651496187	219	41.74	9	219	73	289	5.0e-60	224	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
651496188	920	25.46	61	915	10	856	1.0e-50	195	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
651496189	238	35.19	26	236	2	217	4.0e-46	178	COG3201	Nicotinamide riboside transporter PnuC	222
651496190	232	35.86	4	232	13	248	1.0e-63	236	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
651496192	443	43.11	1	443	26	472	9.0e-105	374	COG0513	Superfamily II DNA and RNA helicase	513
651496195	484	65.19	4	476	3	473	0.0e+00	816	COG0362	6-phosphogluconate dehydrogenase	473
651496197	86	48.19	2	82	3	85	3.0e-22	96.5	COG4545	Glutaredoxin-related protein	85
651496198	232	53.91	1	230	1	230	1.0e-81	296	COG1794	Aspartate/glutamate racemase	230
651496205	232	36.78	1	232	1	236	1.0e-54	206	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
651496206	493	53.89	5	485	7	483	0.0e+00	688	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
651496207	268	37.09	1	268	2	276	2.0e-80	292	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
651496208	666	61.21	5	630	11	624	0.0e+00	656	COG1297	Uncharacterized membrane protein, oligopeptide transporter (OPT) family	624
651496209	182	17.09	35	182	2	157	3.0e-05	41.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
651496210	153	57.89	25	119	5	99	9.0e-28	116	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
651496212	209	47.88	45	209	7	169	6.0e-44	170	COG2862	Uncharacterized membrane protein YqhA	169
651496213	536	36.68	67	523	1	433	1.0e-84	307	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
651496214	235	58.23	1	235	1	237	8.0e-101	359	COG3700	Acid phosphatase (class B)	237
651496215	176	77.84	1	176	4	178	2.0e-78	284	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
651496216	444	75.23	1	444	1	444	0.0e+00	728	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
651496217	222	51.74	12	182	1	172	1.0e-49	190	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
651496218	236	32.91	1	233	1	235	7.0e-32	130	COG3471	Predicted secreted (periplasmic) protein	235
651496219	142	59.29	1	140	1	132	2.0e-38	151	COG3076	Regulator of RNase E activity RraB	135
651496220	340	36.43	10	339	15	401	5.0e-85	308	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
651496221	246	56.35	1	244	1	252	5.0e-91	327	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
651496222	191	30.06	3	165	1	161	6.0e-28	117	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
651496224	405	29.78	144	404	3	263	1.0e-36	147	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
651496225	571	47.54	1	567	1	500	0.0e+00	594	COG0442	Prolyl-tRNA synthetase	500
651496226	224	62.39	1	215	3	220	9.0e-78	283	COG0274	Deoxyribose-phosphate aldolase	228
651496227	171	21.55	38	153	9	107	4.0e-06	44.5	COG0526	Thiol-disulfide isomerase or thioredoxin	127
651496228	327	32.6	21	327	2	310	2.0e-48	186	COG0451	Nucleoside-diphosphate-sugar epimerase	314
651496229	347	38.29	1	346	2	331	1.0e-75	277	COG0859	ADP-heptose:LPS heptosyltransferase	334
651496232	317	33.43	1	317	2	331	2.0e-64	239	COG0859	ADP-heptose:LPS heptosyltransferase	334
651496233	374	19.37	1	374	1	354	5.0e-15	75.8	COG3203	Outer membrane protein (porin)	354
651496234	288	48.25	5	284	2	286	1.0e-92	333	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
651496235	288	29.59	32	284	2	256	7.0e-37	147	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
651496236	538	65.73	9	538	8	529	0.0e+00	843	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
651496238	413	29.02	12	406	14	428	3.0e-51	196	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
651496241	255	46.06	1	253	1	254	2.0e-88	319	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
651496242	327	41.34	9	327	3	330	9.0e-54	204	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
651496243	329	42.47	1	328	1	329	1.0e-49	190	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
651496244	296	47.7	1	295	4	307	4.0e-94	338	COG4594	ABC-type Fe3+-citrate transport system, periplasmic component	310
651496245	288	19.01	1	279	1	277	4.0e-04	39.1	COG5006	Threonine/homoserine efflux transporter RhtA	292
651496246	353	51.72	38	207	1	174	2.0e-61	230	COG0225	Peptide methionine sulfoxide reductase MsrA	174
651496247	158	24.35	29	143	17	127	3.0e-07	48.4	COG0526	Thiol-disulfide isomerase or thioredoxin	127
651496248	181	26.7	6	175	2	177	5.0e-16	77.5	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
651496250	287	53.43	11	286	1	269	2.0e-98	352	COG3716	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID	269
651496251	265	50.76	1	261	2	262	5.0e-67	247	COG3715	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC	265
651496252	327	51.97	166	317	2	153	3.0e-47	182	COG3444	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB	159
651496254	158	40.28	1	144	2	143	8.0e-21	93.3	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
651496257	261	40.45	1	261	6	267	9.0e-68	250	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
651496258	122	33.65	21	122	2	105	1.0e-14	71.9	COG0607	Rhodanese-related sulfurtransferase	110
651496259	293	35.52	2	290	5	276	2.0e-56	212	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
651496260	129	28.18	9	118	9	114	5.0e-08	49.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
651496264	411	39.01	1	408	38	454	7.0e-105	374	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
651496265	293	20.58	42	284	14	235	1.0e-13	70.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
651496266	587	42.2	4	389	2	385	1.0e-66	247	COG0475	Kef-type K+ transport system, membrane component KefB	397
651496268	679	24.31	1	678	1	665	0.0e+00	825	COG4688	Uncharacterized protein	665
651496271	155	42.51	2	155	1	167	1.0e-37	149	COG0629	Single-stranded DNA-binding protein	167
651496272	943	69.46	1	942	3	935	0.0e+00	1614	COG0178	Excinuclease UvrABC ATPase subunit	935
651496276	357	28.24	14	347	14	347	1.0e-41	164	COG3177	Fic family protein	348
651496278	389	41.37	15	349	8	343	1.0e-92	333	COG1566	Multidrug resistance efflux pump	352
651496279	291	33.68	1	290	5	290	2.0e-60	226	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
651496280	163	33.33	12	161	4	152	7.0e-30	123	COG1522	DNA-binding transcriptional regulator, Lrp family	154
651496281	394	60.67	6	394	4	390	0.0e+00	468	COG3004	Na+/H+ antiporter NhaA	390
651496282	467	43.32	35	467	1	431	1.0e-102	367	COG1114	Branched-chain amino acid permeases	431
651496283	246	49.59	5	246	24	260	6.0e-70	257	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
651496284	781	49.51	21	732	1	706	0.0e+00	775	COG0557	Exoribonuclease R	706
651496285	87	63.22	1	87	1	87	3.0e-11	60.3	COG0268	Ribosomal protein S20	88
651496286	524	47.06	1	523	5	517	3.0e-118	419	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
651496287	308	51.79	1	307	1	304	1.0e-103	369	COG0196	FAD synthase	304
651496288	941	52.69	4	935	2	933	0.0e+00	1311	COG0060	Isoleucyl-tRNA synthetase	933
651496289	277	54.67	1	276	1	289	3.0e-100	358	COG2321	Predicted metalloprotease	295
651496291	432	47.51	1	432	1	441	2.0e-115	409	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
651496292	193	75.13	1	193	1	193	3.0e-86	311	COG0740	ATP-dependent protease ClpP, protease subunit	200
651496293	412	70.07	11	411	1	398	0.0e+00	680	COG1219	ATP-dependent protease Clp, ATPase subunit	408
651496294	138	42.47	60	132	1	73	2.0e-09	55	COG0690	Preprotein translocase subunit SecE	73
651496295	185	53.41	8	183	1	176	2.0e-53	202	COG0250	Transcription antitermination factor NusG	178
651496296	142	72.14	2	141	1	139	2.0e-50	191	COG0080	Ribosomal protein L11	141
651496297	229	57.89	1	227	1	228	6.0e-82	297	COG0081	Ribosomal protein L1	228
651496298	381	35.22	1	381	1	384	4.0e-95	341	COG1979	Alcohol dehydrogenase YqhD, Fe-dependent ADH family	384
651496299	393	45.25	1	393	1	387	2.0e-123	436	COG0754	Glutathionylspermidine synthase	387
651496301	235	25.53	7	235	1	225	9.0e-25	107	COG1011	FMN phosphatase YigB, HAD superfamily	229
651496302	139	42.03	1	138	5	138	1.0e-48	185	COG4316	Uncharacterized protein	138
651496303	212	28.37	67	201	1	139	4.0e-19	88.2	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
651496304	436	67.36	1	435	1	423	0.0e+00	626	COG0148	Enolase	423
651496309	545	67.59	3	540	1	530	0.0e+00	919	COG0504	CTP synthase (UTP-ammonia lyase)	533
651496310	456	59.04	4	456	1	459	0.0e+00	676	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
651496311	163	45.78	1	163	4	165	1.0e-34	139	COG0597	Lipoprotein signal peptidase	167
651496312	314	69.49	1	295	2	294	7.0e-130	456	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
651496314	207	53.81	10	205	1	190	1.0e-62	232	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
651496315	105	53.77	1	105	1	106	1.0e-27	114	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
651496316	145	33.33	20	145	29	149	7.0e-17	79.8	COG1555	DNA uptake protein ComE and related DNA-binding proteins	149
651496317	284	52.35	9	284	2	260	8.0e-72	263	COG2116	Formate/nitrite transporter FocA, FNT family	265
651496318	770	65.32	5	769	4	755	0.0e+00	1116	COG1882	Pyruvate-formate lyase	755
651496320	256	36.9	6	256	10	257	4.0e-71	261	COG1180	Pyruvate-formate lyase-activating enzyme	260
651496322	188	43.51	1	131	1	131	9.0e-40	156	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
651496323	340	49.7	4	340	2	339	4.0e-123	434	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
651496324	456	32.55	205	456	1	242	3.0e-25	109	COG3061	Cell envelope opacity-associated protein A (function unknown)	242
651496326	234	41.49	4	234	8	248	3.0e-52	198	COG1381	Recombinational DNA repair protein (RecF pathway)	251
651496327	436	35.94	13	430	1	432	7.0e-111	394	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
651496328	761	53.37	21	761	1	701	0.0e+00	896	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
651496329	118	53.85	1	117	2	118	3.0e-35	139	COG0818	Diacylglycerol kinase	123
651496330	428	29.19	12	427	1	441	2.0e-51	196	COG2610	H+/gluconate symporter or related permease	442
651496331	376	67.47	1	375	1	375	0.0e+00	532	COG1929	Glycerate kinase	378
651496332	297	55.52	1	297	3	300	7.0e-117	413	COG4974	Site-specific recombinase XerD	300
651496333	386	18.21	1	374	10	382	2.0e-03	37.5	COG2814	Predicted arabinose efflux permease, MFS family	394
651496334	272	46.99	7	270	4	265	1.0e-73	269	COG0345	Pyrroline-5-carboxylate reductase	266
651496335	303	59.54	1	302	1	303	2.0e-116	412	COG2974	DNA recombination-dependent growth factor C	303
651496336	616	72.23	6	610	1	603	0.0e+00	1053	COG1217	Predicted membrane GTPase involved in stress response	603
651496337	472	48.31	5	471	1	441	0.0e+00	518	COG0174	Glutamine synthetase	443
651496338	373	28.34	9	372	16	343	8.0e-53	201	COG3765	LPS O-antigen chain length determinant protein, WzzB/FepE family	347
651496340	296	16.55	1	296	2	280	2.0e-11	63.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
651496341	358	24.4	1	357	1	373	1.0e-27	117	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651496342	366	25.33	1	364	3	376	2.0e-33	136	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651496343	386	22.97	33	386	28	376	2.0e-28	120	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651496344	301	25.19	3	235	1	264	6.0e-26	111	COG0451	Nucleoside-diphosphate-sugar epimerase	314
651496345	182	39.78	1	181	40	225	2.0e-44	171	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
651496346	638	41.99	24	635	1	588	0.0e+00	606	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
651496347	415	21.07	17	405	32	414	5.0e-11	62.5	COG3307	O-antigen ligase	424
651496348	337	64.48	3	336	1	320	0.0e+00	540	COG1088	dTDP-D-glucose 4,6-dehydratase	340
651496349	433	38.84	1	428	28	480	8.0e-122	430	COG0260	Leucyl aminopeptidase	485
651496350	139	66.67	1	135	1	135	2.0e-57	214	COG0105	Nucleoside diphosphate kinase	135
651496351	243	34.85	1	230	2	242	6.0e-57	214	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
651496352	325	38.34	11	324	9	334	1.0e-39	157	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
651496354	640	27.19	1	640	1	608	2.0e-70	261	COG4206	Outer membrane cobalamin receptor protein	608
651496355	302	80.6	4	302	1	297	0.0e+00	562	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
651496356	217	40.48	2	201	1	202	2.0e-41	162	COG5514	Uncharacterized protein	203
651496357	86	51.81	2	82	3	85	2.0e-24	103	COG4545	Glutaredoxin-related protein	85
651496360	121	48.76	1	121	8	126	1.0e-35	141	COG2852	Very-short-patch-repair endonuclease	129
651496361	156	19.18	3	148	5	137	1.0e-17	82.7	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
651496362	688	59.19	1	688	1	690	0.0e+00	944	COG0751	Glycyl-tRNA synthetase, beta subunit	691
651496366	351	25.81	11	345	1	332	6.0e-61	228	COG0859	ADP-heptose:LPS heptosyltransferase	334
651496367	114	36.46	11	106	19	114	1.0e-14	71.6	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
651496369	614	35.16	26	607	1	567	8.0e-116	411	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
651496370	174	42.7	1	174	1	176	1.0e-35	143	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
651496371	56	54.39	1	56	1	57	1.0e-11	61.4	COG0333	Ribosomal protein L32	57
651496372	339	47.77	3	339	1	334	1.0e-111	396	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
651496373	317	58.07	1	317	1	322	1.0e-115	409	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
651496374	312	56.96	1	309	1	309	3.0e-105	375	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
651496375	242	46.61	1	239	3	250	2.0e-53	201	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651496376	76	68.42	1	76	4	79	5.0e-12	62.6	COG0236	Acyl carrier protein	80
651496378	414	41.33	1	413	2	412	1.0e-111	396	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
651496379	242	44.62	1	241	4	250	2.0e-44	172	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
651496380	150	35.48	6	126	7	130	4.0e-22	97.4	COG4706	Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain	161
651496381	406	30.77	9	402	11	409	4.0e-65	242	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
651496383	758	23.42	15	758	20	781	1.0e-56	215	COG4258	Predicted exporter	788
651496384	194	19.39	1	186	7	193	1.0e-05	43.1	COG2834	Outer membrane lipoprotein-sorting protein	211
651496385	147	25.86	9	123	6	119	1.0e-16	79.1	COG0824	Acyl-CoA thioesterase FadM	137
651496386	312	32.68	8	309	1	300	5.0e-50	191	COG4261	Predicted acyltransferase, LPLAT superfamily	309
651496387	242	17.7	2	237	1	235	1.0e-07	50.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
651496388	435	19.68	13	421	36	519	2.0e-25	110	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
651496389	185	32.22	14	183	15	194	1.0e-24	105	COG4648	Uncharacterized membrane protein	201
651496390	560	19.43	14	430	37	518	5.0e-32	132	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
651496391	83	24.36	1	78	1	78	2.0e-06	44.1	COG0236	Acyl carrier protein	80
651496392	87	25	1	84	4	79	2.0e-04	37.2	COG0236	Acyl carrier protein	80
651496393	257	23.14	27	255	6	247	1.0e-14	73.4	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
651496398	328	20.94	24	325	50	409	1.0e-20	94.2	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
651496399	96	27.59	7	93	1	79	8.0e-04	35.3	COG0236	Acyl carrier protein	80
651496400	413	22.86	201	408	81	284	5.0e-12	66.1	COG0842	ABC-type multidrug transport system, permease component	286
651496401	240	40.85	1	231	4	237	7.0e-61	227	COG1131	ABC-type multidrug transport system, ATPase component	293
651496405	386	20.16	7	380	4	319	1.0e-36	147	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
651496408	180	51.19	4	171	2	167	4.0e-58	217	COG0703	Shikimate kinase	172
651496409	362	60.56	1	360	1	359	0.0e+00	510	COG0337	3-dehydroquinate synthetase	360
651496410	284	48	14	283	1	272	9.0e-73	267	COG0338	Site-specific DNA-adenine methylase	274
651496413	898	59.12	1	888	2	822	0.0e+00	1089	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
651496414	134	25.9	1	134	4	141	3.0e-10	57.7	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
651496415	554	19.29	4	554	30	631	1.0e-58	221	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
651496416	345	31.88	4	345	1	332	6.0e-51	194	COG1466	DNA polymerase III, delta subunit	334
651496417	167	45.83	2	167	1	168	5.0e-48	183	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
651496418	862	53.23	1	859	1	814	0.0e+00	1093	COG0495	Leucyl-tRNA synthetase	814
651496419	95	45.45	1	95	3	101	7.0e-22	95.4	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
651496420	181	43.82	91	178	7	95	1.0e-05	43.2	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
651496421	315	33.13	1	315	4	322	8.0e-66	244	COG0598	Mg2+ and Co2+ transporter CorA	322
651496422	199	35	1	199	7	204	2.0e-51	195	COG3056	Uncharacterized lipoprotein YajG	204
651496423	113	43.68	11	96	2	88	2.0e-21	94.3	COG0271	Stress-induced morphogen (activity unknown)	90
651496424	447	73.21	1	447	1	447	0.0e+00	727	COG1726	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA	447
651496425	411	68.64	2	406	1	400	0.0e+00	525	COG1805	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB	400
651496426	263	58.71	1	263	2	262	1.0e-91	329	COG2869	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC	264
651496427	209	82.78	1	209	1	208	8.0e-92	329	COG1347	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD	208
651496428	198	83.33	1	198	1	198	6.0e-79	286	COG2209	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE	198
651496429	411	86.83	2	411	1	410	0.0e+00	781	COG2871	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF	410
651496430	346	45.64	2	343	1	337	8.0e-104	370	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
651496431	86	57.33	1	75	1	75	9.0e-25	105	COG2991	Uncharacterized protein	77
651496432	384	60.99	22	383	1	356	0.0e+00	505	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
651496433	449	45.35	21	449	1	411	0.0e+00	514	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
651496434	340	61.85	9	333	5	327	0.0e+00	529	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
651496435	264	52.02	2	246	1	248	8.0e-68	250	COG0805	Sec-independent protein secretion pathway component TatC	255
651496436	201	39.22	1	102	1	94	2.0e-12	65.8	COG1826	Sec-independent protein translocase protein TatA	94
651496437	76	41.33	1	75	1	75	2.0e-11	61.1	COG1826	Sec-independent protein translocase protein TatA	94
651496440	603	26.01	10	595	1	516	2.0e-70	260	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
651496443	420	79.52	1	420	4	421	0.0e+00	725	COG1158	Transcription termination factor Rho	422
651496444	457	54.7	1	457	3	458	0.0e+00	655	COG0165	Argininosuccinate lyase	459
651496448	615	18.85	213	568	81	425	3.0e-18	87.4	COG0286	Type I restriction-modification system, DNA methylase subunit	489
651496451	345	21.15	42	142	31	129	8.0e-05	41.5	COG3677	Transposase	129
651496455	163	68.71	1	163	4	165	3.0e-62	230	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
651496456	314	47.39	100	309	2	212	3.0e-62	232	COG0560	Phosphoserine phosphatase	212
651496457	232	33.02	17	228	9	214	5.0e-41	161	COG3726	Uncharacterized membrane protein affecting hemolysin expression	214
651496458	665	67.92	1	665	3	662	0.0e+00	1084	COG0021	Transketolase	663
651496459	456	52.67	1	447	2	449	0.0e+00	512	COG1115	Na+/alanine symporter	452
651496460	107	45.71	1	103	1	105	6.0e-26	109	COG1544	Ribosome-associated translation inhibitor RaiA	110
651496462	464	56.21	21	461	1	443	0.0e+00	594	COG4623	Membrane-bound lytic murein transglycosylase MltF	473
651496463	612	38.61	6	516	30	513	2.0e-124	439	COG0513	Superfamily II DNA and RNA helicase	513
651496464	283	52.55	2	275	26	297	7.0e-108	383	COG4785	Lipoprotein NlpI, contains TPR repeats	297
651496465	712	65.08	1	693	2	692	0.0e+00	1014	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
651496467	155	41.67	1	155	1	154	2.0e-42	165	COG2731	Beta-galactosidase, beta subunit	154
651496468	73	43.66	4	73	7	76	8.0e-12	62.2	COG0425	TusA-related sulfurtransferase	78
651496470	434	56.48	1	431	1	432	0.0e+00	473	COG3681	L-cysteine desulfidase	433
651496471	104	22.12	2	101	10	109	5.0e-07	46.2	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
651496472	932	60.67	336	932	3	593	0.0e+00	808	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
651496473	101	47.83	4	95	2	93	6.0e-16	75.7	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
651496474	241	62.44	38	241	1	204	4.0e-88	317	COG1636	Predicted ATPase, Adenine nucleotide alpha hydrolases (AANH) superfamily	204
651496477	331	38.46	14	331	3	322	4.0e-80	291	COG0142	Geranylgeranyl pyrophosphate synthase	322
651496478	103	63.11	1	103	1	103	2.0e-34	136	COG0261	Ribosomal protein L21	103
651496479	85	77.65	1	85	1	84	9.0e-30	121	COG0211	Ribosomal protein L27	87
651496480	183	25	9	139	5	136	1.0e-03	36.7	COG2510	Uncharacterized membrane protein	140
651496482	390	60.65	1	368	1	369	0.0e+00	537	COG0536	GTPase involved in cell partioning and DNA repair	369
651496483	45	60	1	40	1	38	3.0e-04	36.7	COG0257	Ribosomal protein L36	38
651496484	88	37.93	1	87	1	75	4.0e-18	82.6	COG0254	Ribosomal protein L31	75
651496485	160	59.48	7	159	2	153	2.0e-54	204	COG0691	tmRNA-binding protein	153
651496486	237	41.2	4	234	1	228	2.0e-54	205	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
651496487	589	44.67	2	585	1	566	0.0e+00	583	COG4232	Thiol:disulfide interchange protein	569
651496488	132	33.08	7	132	11	138	4.0e-11	60.4	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
651496489	532	65.41	5	532	1	515	0.0e+00	824	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
651496490	427	63.64	1	427	1	427	0.0e+00	634	COG0151	Phosphoribosylamine-glycine ligase	428
651496491	412	22.44	16	397	20	409	8.0e-25	108	COG2848	Uncharacterized conserved protein, UPF0210 family	445
651496495	421	65.3	6	419	5	412	0.0e+00	673	COG0112	Glycine/serine hydroxymethyltransferase	413
651496496	569	33.46	317	569	7	275	8.0e-28	118	COG0790	TPR repeat	292
651496497	91	35.96	2	90	4	92	4.0e-11	59.9	COG3326	Uncharacterized membrane protein YsdA, DUF1294 family	94
651496498	177	38.01	1	168	1	169	7.0e-27	113	COG1495	Disulfide bond formation protein DsbB	170
651496499	512	75.68	1	512	3	516	0.0e+00	803	COG3067	Na+/H+ antiporter NhaB	516
651496500	293	22.5	59	289	3	241	8.0e-35	140	COG2186	DNA-binding transcriptional regulator, FadR family	241
651496501	263	44.94	20	261	1	246	4.0e-75	274	COG1385	16S rRNA U1498 N3-methylase RsmE	246
651496502	186	46.81	1	186	10	194	9.0e-62	229	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
651496503	139	42.75	2	138	1	138	8.0e-43	165	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
651496504	245	51.39	1	245	1	249	2.0e-85	309	COG1496	Copper oxidase (laccase) domain	249
651496505	324	45.36	6	302	2	289	4.0e-80	291	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
651496506	273	37.5	12	270	1	254	8.0e-61	227	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
651496508	856	58.36	5	853	1	780	0.0e+00	991	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
651496509	201	43.18	9	183	8	169	8.0e-49	186	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
651496510	112	69.64	1	112	1	112	4.0e-40	156	COG0347	Nitrogen regulatory protein PII	112
651496511	346	27.67	5	346	11	355	7.0e-34	138	COG0628	Predicted PurR-regulated permease PerM	355
651496512	324	48.2	17	320	1	305	6.0e-87	314	COG0341	Preprotein translocase subunit SecF	305
651496513	616	47.71	75	616	1	506	0.0e+00	479	COG0342	Preprotein translocase subunit SecD	506
651496514	96	44.79	1	96	3	97	6.0e-25	105	COG1862	Preprotein translocase subunit YajC	97
651496515	75	30.51	3	60	6	64	1.0e-07	48.3	COG0425	TusA-related sulfurtransferase	78
651496517	382	61.6	3	377	1	370	0.0e+00	561	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
651496518	363	55.8	1	359	1	348	0.0e+00	513	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
651496519	116	20.91	17	107	14	123	9.0e-04	35.7	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
651496520	459	41.21	1	396	1	347	2.0e-113	403	COG0826	Collagenase-like protease, PrtC family	347
651496521	438	47.37	1	436	3	436	6.0e-103	367	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
651496522	176	41.38	2	175	1	171	1.0e-47	182	COG0221	Inorganic pyrophosphatase	171
651496524	1077	19.81	572	1077	82	577	1.0e-12	69.3	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
651496525	338	47.63	1	336	1	329	0.0e+00	499	COG1087	UDP-glucose 4-epimerase	329
651496527	214	41.74	1	214	1	178	2.0e-51	195	COG0563	Adenylate kinase or related kinase	178
651496529	320	64.61	13	320	1	306	0.0e+00	514	COG0320	Lipoate synthase	306
651496530	213	56.8	6	209	11	213	5.0e-84	303	COG0321	Lipoate-protein ligase B	221
651496531	92	52.22	5	92	1	90	2.0e-26	110	COG2921	Putative lipoic acid-binding regulatory protein	90
651496532	395	48.48	1	394	2	389	7.0e-117	414	COG1686	D-alanyl-D-alanine carboxypeptidase	389
651496533	202	45.45	17	188	28	200	2.0e-41	162	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
651496534	371	41.89	12	369	9	377	3.0e-79	289	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
651496535	658	36.72	16	627	4	595	0.0e+00	493	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
651496536	155	54.19	1	154	1	155	1.0e-64	238	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
651496537	102	45.1	1	102	4	105	2.0e-32	130	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
651496538	550	53.09	1	549	1	543	0.0e+00	588	COG2985	Uncharacterized membrane protein YbjL, putative transporter	544
651496539	596	41.75	13	589	1	593	0.0e+00	623	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
651496540	351	66.37	7	348	2	341	0.0e+00	463	COG1077	Actin-like ATPase involved in cell morphogenesis	342
651496541	354	38.38	3	272	1	271	2.0e-67	249	COG1792	Cell shape-determining protein MreC	284
651496542	162	45.06	1	161	1	162	4.0e-19	87.6	COG2891	Cell shape-determining protein MreD	167
651496543	419	45.66	1	398	21	418	9.0e-111	393	COG0513	Superfamily II DNA and RNA helicase	513
651496544	97	30.59	5	89	5	88	6.0e-16	75.7	COG2388	Predicted acetyltransferase, GNAT superfamily	99
651496545	68	60	1	65	1	65	3.0e-18	83.2	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
651496546	207	40.2	1	204	1	200	1.0e-51	196	COG0237	Dephospho-CoA kinase	201
651496547	225	24.69	1	220	2	238	8.0e-07	47.7	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
651496548	407	32.35	4	407	1	397	1.0e-75	277	COG1459	Type II secretory pathway, component PulF	397
651496549	459	42.5	26	457	21	499	0.0e+00	471	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
651496550	165	37.3	25	149	1	125	3.0e-24	105	COG4969	Tfp pilus assembly protein, major pilin PilA	125
651496551	187	50.81	3	183	1	180	8.0e-61	226	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
651496552	197	23.38	6	153	8	152	3.0e-12	65.4	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
651496553	264	28.52	1	264	3	253	3.0e-11	62.3	COG0730	Uncharacterized membrane protein YfcA	258
651496554	269	43.77	1	264	1	278	3.0e-64	238	COG0682	Prolipoprotein diacylglyceryltransferase	287
651496555	283	39.58	1	283	3	268	3.0e-91	328	COG0207	Thymidylate synthase	268
651496556	172	52.67	1	150	3	152	9.0e-53	199	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
651496557	219	64.38	1	219	4	222	3.0e-103	367	COG0692	Uracil DNA glycosylase	223
651496558	127	85.83	1	127	1	127	2.0e-64	237	COG3445	Autonomous glycyl radical cofactor GrcA	127
651496560	607	71.24	10	606	6	603	0.0e+00	1085	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
651496561	349	29.73	86	210	9	156	8.0e-15	75	COG0681	Signal peptidase I	166
651496562	227	50.66	4	227	8	232	7.0e-70	257	COG0571	dsRNA-specific ribonuclease	235
651496563	304	54.21	9	304	3	298	6.0e-117	413	COG1159	GTPase Era, involved in 16S rRNA processing	298
651496564	201	28.5	14	201	1	190	6.0e-16	77.4	COG0558	Phosphatidylglycerophosphate synthase	192
651496566	310	54.07	3	309	2	302	1.0e-102	366	COG4589	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase	303
651496567	407	37.53	11	406	1	393	9.0e-100	357	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
651496568	426	37.91	11	423	4	422	9.0e-100	357	COG1169	Isochorismate synthase EntC	423
651496569	568	46.69	1	566	1	566	0.0e+00	690	COG1165	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase	566
651496571	253	23.08	7	245	21	277	2.0e-16	79.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
651496572	438	19.11	68	428	63	386	1.0e-06	48.3	COG2814	Predicted arabinose efflux permease, MFS family	394
651496573	364	25.83	7	359	4	330	6.0e-59	221	COG0620	Methionine synthase II (cobalamin-independent)	330
651496574	400	48.53	4	399	3	405	0.0e+00	490	COG2081	Predicted flavoprotein YhiN	408
651496575	351	49.26	1	136	1	136	5.0e-46	178	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
651496576	176	21.71	30	153	1	127	3.0e-09	55.3	COG0526	Thiol-disulfide isomerase or thioredoxin	127
651496577	634	47.98	1	631	1	641	0.0e+00	600	COG1138	Cytochrome c biogenesis factor	648
651496578	321	51.55	3	321	1	305	1.0e-73	270	COG3301	Formate-dependent nitrite reductase, membrane component NrfD	305
651496579	225	45.73	31	225	3	200	6.0e-56	210	COG0437	Fe-S-cluster-containing dehydrogenase component	203
651496581	510	59.21	1	504	14	497	0.0e+00	726	COG3303	Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit	501
651496583	239	41	1	239	1	227	4.0e-47	181	COG1811	Uncharacterized membrane protein YqgA, affects biofilm formation	228
651496584	271	54.58	1	269	1	273	1.0e-103	369	COG0266	Formamidopyrimidine-DNA glycosylase	273
651496585	56	56	5	54	1	50	1.0e-10	58.3	COG0267	Ribosomal protein L33	50
651496586	78	64.94	1	76	1	77	9.0e-22	95	COG0227	Ribosomal protein L28	77
651496587	221	53.46	5	221	8	224	4.0e-73	267	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
651496588	400	52.27	2	396	1	389	2.0e-119	422	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
651496589	151	56.95	1	151	1	148	4.0e-54	203	COG0756	dUTPase	148
651496590	217	19.53	28	196	10	175	4.0e-06	45.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
651496591	72	61.11	1	72	1	72	2.0e-22	97	COG3089	Uncharacterized conserved protein YheU, UPF0270 family	72
651496592	222	31.37	20	222	12	214	2.0e-38	152	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
651496593	488	37.68	1	403	3	393	1.0e-69	257	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
651496594	278	63.32	50	276	1	229	3.0e-95	341	COG3010	Putative N-acetylmannosamine-6-phosphate epimerase	229
651496595	312	33.76	12	306	6	314	1.0e-50	193	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
651496596	288	41.05	3	287	1	281	4.0e-64	238	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
651496597	292	32.88	1	292	2	295	5.0e-71	261	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
651496598	267	40.24	1	249	1	238	4.0e-67	248	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
651496599	381	50.79	2	379	1	378	5.0e-123	434	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
651496600	360	41.21	1	357	1	363	7.0e-114	404	COG1195	Recombinational DNA repair ATPase RecF	363
651496601	367	42.23	2	367	1	364	1.0e-96	346	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
651496602	455	48.76	7	451	1	408	0.0e+00	463	COG0593	Chromosomal replication initiation ATPase DnaA	408
651496603	44	84.09	1	44	1	44	3.0e-03	33.7	COG0230	Ribosomal protein L34	44
651496604	111	41.44	1	110	7	117	2.0e-23	100	COG0594	RNase P protein component	117
651496605	87	63.64	3	79	1	77	1.0e-28	118	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
651496606	542	48.21	245	542	4	307	7.0e-82	298	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
651496607	452	55.36	1	452	3	454	0.0e+00	570	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
651496608	185	48.13	1	182	1	187	8.0e-35	139	COG1971	Putative Mn2+ efflux pump MntP	190
651496610	116	44.35	4	116	2	113	2.0e-27	114	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
651496611	115	31.2	1	114	1	121	2.0e-13	68.1	COG5633	Uncharacterized conserved protein YcfL	123
651496612	347	40.62	1	347	5	352	1.0e-81	296	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
651496613	390	34.72	1	382	64	432	4.0e-91	328	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
651496614	277	48.91	4	276	1	274	7.0e-53	200	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
651496615	283	45.96	1	271	1	272	1.0e-51	196	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
651496616	298	48.21	6	256	3	252	8.0e-90	323	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
651496617	293	44.22	4	293	11	303	9.0e-83	300	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
651496620	382	57.46	14	365	1	349	0.0e+00	470	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
651496621	180	44.38	9	180	7	184	2.0e-43	168	COG3063	Tfp pilus assembly protein PilF	250
651496622	342	28.81	13	304	2	276	3.0e-35	142	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
651496623	368	63.71	8	368	1	361	0.0e+00	542	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
651496624	423	49.77	2	423	1	428	0.0e+00	512	COG0124	Histidyl-tRNA synthetase	429
651496625	204	45.85	1	204	1	205	5.0e-44	170	COG2976	Putative negative regulator of RcsB-dependent stress response	207
651496626	147	23.29	6	147	37	182	7.0e-16	76.6	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
651496627	214	58.85	1	205	2	200	1.0e-76	279	COG0605	Superoxide dismutase	204
651496628	213	54.33	5	210	1	207	2.0e-75	275	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
651496629	221	65.45	1	220	2	221	1.0e-52	199	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
651496630	246	41.87	1	245	34	279	2.0e-45	175	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
651496631	67	47.76	1	67	1	67	8.0e-21	91.9	COG3114	Heme exporter protein D	67
651496632	176	56.25	1	160	1	153	5.0e-55	207	COG2332	Cytochrome c-type biogenesis protein CcmE	153
651496633	649	58.42	1	646	1	646	0.0e+00	740	COG1138	Cytochrome c biogenesis factor	648
651496634	181	29.23	33	157	1	127	6.0e-11	60.7	COG0526	Thiol-disulfide isomerase or thioredoxin	127
651496635	154	46.1	1	152	2	153	6.0e-48	183	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
651496636	305	33.77	1	299	1	287	1.0e-64	240	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
651496637	132	25.71	6	129	1	138	7.0e-10	56.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
651496641	415	40.81	1	415	1	441	6.0e-91	327	COG2233	Xanthine/uracil permease	451
651496642	208	62.68	1	208	2	210	2.0e-80	292	COG0035	Uracil phosphoribosyltransferase	210
651496644	747	48.8	3	747	1	717	0.0e+00	692	COG3256	Nitric oxide reductase large subunit	717
651496646	463	64.89	1	449	1	448	0.0e+00	629	COG0541	Signal recognition particle GTPase	451
651496647	261	37.4	1	261	3	258	6.0e-44	171	COG4137	ABC-type uncharacterized transport system, permease component	265
651496648	431	60	14	431	1	418	0.0e+00	571	COG4536	Mg2+ and Co2+ transporter CorB, contains DUF21, CBS pair, and CorC-HlyC domains	423
651496649	322	66.04	2	318	26	343	6.0e-124	437	COG0709	Selenophosphate synthase	346
651496650	605	41.79	1	597	12	610	0.0e+00	678	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
651496651	339	63.72	2	337	1	333	0.0e+00	463	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
651496652	229	60.53	22	211	1	186	3.0e-76	278	COG0194	Guanylate kinase	191
651496653	88	50	1	65	1	66	4.0e-11	59.9	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
651496654	706	41.38	1	702	6	701	0.0e+00	810	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
651496655	693	55.28	1	686	1	677	0.0e+00	933	COG1200	RecG-like helicase	677
651496656	263	41.73	1	263	3	266	3.0e-80	292	COG0796	Glutamate racemase	269
651496657	977	47.56	1	976	1	954	0.0e+00	1085	COG1391	Glutamine synthetase adenylyltransferase	963
651496658	317	52.19	7	302	1	294	3.0e-104	371	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
651496659	615	39.9	3	596	4	615	0.0e+00	584	COG0323	DNA mismatch repair ATPase MutL	638
651496660	537	37.22	26	248	44	227	9.0e-48	185	COG0860	N-acetylmuramoyl-L-alanine amidase	231
651496661	156	50	4	156	1	149	5.0e-44	170	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
651496664	200	75.69	19	199	1	181	2.0e-88	317	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
651496665	345	41.85	31	343	3	301	1.0e-100	359	COG1162	Putative ribosome biogenesis GTPase RsgA	301
651496666	85	53.09	1	81	1	81	3.0e-24	103	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
651496667	575	60.03	1	573	2	574	0.0e+00	808	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
651496668	166	53.55	14	166	2	156	7.0e-47	180	COG2190	Phosphotransferase system IIA component	156
651496670	1008	29.19	39	897	7	808	2.0e-113	403	COG3250	Beta-galactosidase/beta-glucuronidase	808
651496671	87	39.51	1	81	1	76	2.0e-17	80.8	COG0695	Glutaredoxin	80
651496672	299	33.44	1	298	1	316	1.0e-64	240	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
651496674	464	68.83	1	462	1	461	0.0e+00	799	COG0114	Fumarate hydratase class II	462
651496676	143	47.55	3	143	2	141	4.0e-36	143	COG2927	DNA polymerase III, chi subunit	144
651496678	104	77.45	2	103	4	105	4.0e-42	162	COG3097	Uncharacterized protein YqfB, UPF0267 family	106
651496681	968	55.73	21	967	1	877	0.0e+00	1248	COG0525	Valyl-tRNA synthetase	877
651496682	1025	30.84	28	543	8	459	5.0e-80	293	COG0277	FAD/FMN-containing dehydrogenase	459
651496683	366	30.98	183	365	16	190	4.0e-29	122	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
651496684	193	46.07	1	190	1	185	2.0e-50	191	COG1704	Uncharacterized conserved protein	185
651496685	149	35.71	1	148	59	212	2.0e-33	135	COG3762	Uncharacterized membrane protein	213
651496686	266	36.5	7	266	5	271	3.0e-52	199	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
651496687	108	61.54	1	103	2	105	2.0e-43	166	COG0278	Glutaredoxin-related protein	105
651496688	332	47.92	1	332	4	336	2.0e-97	349	COG4143	ABC-type thiamine transport system, periplasmic component	336
651496689	534	32.58	10	533	9	535	5.0e-79	289	COG1178	ABC-type Fe3+ transport system, permease component	540
651496690	209	62.02	1	208	1	208	8.0e-85	306	COG3840	ABC-type thiamine transport system, ATPase component	231
651496691	338	54.29	13	336	6	329	2.0e-119	422	COG0502	Biotin synthase or related enzyme	335
651496692	266	46.92	1	258	1	260	4.0e-82	298	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
651496693	172	16.07	3	170	8	148	1.0e-05	43.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
651496694	241	27.5	3	239	2	194	2.0e-29	122	COG4795	Type II secretory pathway, component PulJ	194
651496697	1119	38.39	1	1119	1	1073	0.0e+00	923	COG1330	Exonuclease V gamma subunit	1078
651496698	149	59.73	1	149	1	149	5.0e-59	220	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
651496699	376	69.66	5	149	2	146	2.0e-62	233	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
651496700	340	39.12	9	337	4	341	6.0e-59	221	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
651496701	197	37.5	6	195	6	191	5.0e-36	144	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
651496702	256	53.49	4	132	2	130	4.0e-40	158	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
651496703	253	44.53	7	252	14	256	6.0e-57	214	COG0725	ABC-type molybdate transport system, periplasmic component	258
651496704	238	59.73	7	232	1	225	5.0e-72	264	COG4149	ABC-type molybdate transport system, permease component	225
651496705	351	59.43	1	350	1	350	0.0e+00	512	COG4148	ABC-type molybdate transport system, ATPase component	352
651496706	442	63.27	1	439	5	445	0.0e+00	531	COG1823	L-cystine uptake protein TcyP, sodium:dicarboxylate symporter family	458
651496707	378	61.54	1	375	1	371	0.0e+00	496	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
651496708	422	57.35	1	421	6	426	0.0e+00	626	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
651496709	132	25.49	1	131	6	157	1.0e-16	78.5	COG3708	Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain	157
651496710	633	62.38	1	605	4	579	0.0e+00	674	COG0443	Molecular chaperone DnaK (HSP70)	579
651496711	499	25.75	3	492	1	479	3.0e-55	209	COG5339	Uncharacterized conserved protein YdgA, DUF945 family	479
651496712	152	61.87	10	148	3	141	4.0e-62	230	COG1803	Methylglyoxal synthase	142
651496713	888	68.8	1	888	1	887	0.0e+00	1410	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
651496714	630	43.02	196	630	1	403	8.0e-103	368	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
651496715	474	54.05	3	456	1	454	0.0e+00	498	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
651496716	183	30.73	12	180	21	197	2.0e-24	105	COG0791	Cell wall-associated hydrolase, NlpC family	197
651496719	413	64.81	1	412	2	405	0.0e+00	559	COG3633	Na+/serine symporter	407
651496720	482	46.09	226	477	1	253	7.0e-77	281	COG1119	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA	257
651496721	304	42.67	4	296	2	291	2.0e-54	206	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
651496722	151	41.38	6	149	1	140	2.0e-22	98.4	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
651496723	201	33.5	1	195	1	189	1.0e-45	176	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
651496724	194	41.41	9	192	1	198	4.0e-36	144	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
651496725	881	56.32	3	868	2	804	0.0e+00	1023	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
651496726	598	42.72	10	432	1	398	1.0e-124	440	COG1944	Ribosomal protein S12 methylthiotransferase accessory factor YcaO	398
651496727	112	56.14	2	58	1	57	2.0e-13	67.2	COG3422	Uncharacterized conserved protein YegP, UPF0339 family	59
651496729	233	24.8	3	215	17	247	3.0e-20	92.6	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
651496730	440	45.71	1	431	1	411	8.0e-119	420	COG0373	Glutamyl-tRNA reductase	414
651496731	247	35.34	1	243	5	248	5.0e-46	177	COG3698	Uncharacterized protein YigE, DUF2233 family	250
651496736	527	74.38	1	527	2	528	0.0e+00	931	COG4108	Peptide chain release factor RF-3	528
651496741	346	21.16	42	275	2	236	3.0e-12	66.6	COG0790	TPR repeat	292
651496743	289	34.62	6	288	1	246	3.0e-68	252	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
651496744	276	19.8	1	264	1	296	2.0e-16	79.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
651496745	444	35.61	9	430	1	403	0.0e+00	469	COG0137	Argininosuccinate synthase	403
651496746	358	48.88	1	353	1	342	2.0e-106	379	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
651496747	271	58.87	6	270	18	282	2.0e-89	322	COG4208	ABC-type sulfate transport system, permease component	287
651496748	273	52.81	2	268	6	272	2.0e-61	229	COG0555	ABC-type sulfate transport system, permease component	274
651496749	335	44.78	5	328	14	348	3.0e-96	345	COG1613	ABC-type sulfate transport system, periplasmic component	348
651496750	476	61.32	214	454	4	244	2.0e-88	319	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
651496751	245	38.37	6	245	5	242	5.0e-54	204	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
651496752	307	32.06	1	307	9	261	2.0e-49	189	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
651496753	427	56.44	3	427	2	413	0.0e+00	577	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
651496754	601	53.47	15	601	5	587	0.0e+00	643	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
651496755	588	42.7	12	572	1	509	0.0e+00	521	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
651496756	144	48.25	1	143	4	145	3.0e-37	147	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
651496757	174	40	1	168	1	151	2.0e-31	128	COG0716	Flavodoxin	151
651496758	261	22.26	8	260	9	281	7.0e-27	114	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
651496759	213	47.14	1	210	1	181	1.0e-64	239	COG3057	Negative regulator of replication initiation	181
651496760	450	26.21	1	447	13	525	2.0e-72	266	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
651496761	1114	37.11	207	1106	2	823	0.0e+00	697	COG3264	Small-conductance mechanosensitive channel	835
651496762	357	62.15	2	357	1	357	0.0e+00	545	COG0082	Chorismate synthase	369
651496763	290	57.19	6	290	1	284	1.0e-120	426	COG3770	Murein endopeptidase	284
651496764	255	32.43	2	254	1	258	2.0e-17	83.5	COG0730	Uncharacterized membrane protein YfcA	258
651496765	319	37.13	16	318	2	308	3.0e-88	318	COG1560	Lauroyl/myristoyl acyltransferase	308
651496766	180	52.51	1	179	1	179	6.0e-52	197	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
651496767	714	40	1	457	1	473	2.0e-123	437	COG2812	DNA polymerase III, gamma/tau subunits	515
651496768	282	49.83	1	280	1	303	5.0e-80	291	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
651496769	417	58.51	1	417	4	417	0.0e+00	597	COG0014	Gamma-glutamyl phosphate reductase	417
651496771	220	56.25	1	208	4	208	1.0e-64	239	COG2860	Uncharacterized membrane protein YeiH	209
651496773	292	24.16	17	284	21	284	2.0e-04	40.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
651496774	72	52.94	1	68	1	68	7.0e-13	65.7	COG2841	Uncharacterized conserved protein YdcH, DUF465 family	72
651496775	429	59.03	1	429	1	427	0.0e+00	593	COG0172	Seryl-tRNA synthetase	429
651496776	314	28.93	5	314	5	322	3.0e-38	152	COG1275	Tellurite resistance protein TehA and related permeases	329
651496777	237	32.62	1	233	6	236	4.0e-44	171	COG2188	DNA-binding transcriptional regulator, GntR family	236
651496778	501	37.21	1	501	11	519	3.0e-130	459	COG1640	4-alpha-glucanotransferase	520
651496779	755	39.69	8	752	17	747	0.0e+00	718	COG0058	Glucan phosphorylase	750
651496780	263	21.27	1	261	10	255	8.0e-20	91.2	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
651496781	554	27.06	2	455	1	391	9.0e-53	201	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
651496782	659	58.33	1	658	1	644	0.0e+00	1056	COG4776	Exoribonuclease II	645
651496783	285	64.86	24	282	1	258	3.0e-112	398	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
651496784	252	45.45	2	252	1	250	4.0e-74	271	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
651496785	311	50.48	5	310	2	307	5.0e-95	341	COG1560	Lauroyl/myristoyl acyltransferase	308
651496786	476	61.05	1	475	1	467	0.0e+00	720	COG2870	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase	467
651496787	662	19.01	1	662	1	608	2.0e-33	137	COG4206	Outer membrane cobalamin receptor protein	608
651496789	332	28.03	1	291	7	308	4.0e-26	112	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
651496790	337	45.27	6	337	1	331	4.0e-57	215	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
651496791	249	37.65	3	248	2	248	3.0e-70	258	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
651496792	244	31.56	4	242	14	256	2.0e-37	148	COG0725	ABC-type molybdate transport system, periplasmic component	258
651496793	265	37.64	1	262	4	266	3.0e-53	202	COG0555	ABC-type sulfate transport system, permease component	274
651496795	281	33.68	1	281	2	280	7.0e-71	260	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
651496796	346	26.52	16	323	29	319	1.0e-42	167	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
651496797	337	40.83	3	333	2	333	3.0e-53	202	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
651496798	258	37.94	4	242	2	253	1.0e-63	236	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
651496799	238	26.94	1	235	29	254	7.0e-28	117	COG0725	ABC-type molybdate transport system, periplasmic component	258
651496800	679	59.32	1	679	8	683	0.0e+00	993	COG0339	Zn-dependent oligopeptidase	683
651496801	154	41.59	31	143	1	113	3.0e-22	98	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
651496802	520	30.38	52	518	33	562	4.0e-72	265	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
651496804	1149	30.54	615	1138	7	519	2.0e-78	287	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
651496805	343	32.9	29	332	5	284	2.0e-62	233	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
651496807	296	28.77	6	292	1	292	4.0e-40	158	COG0583	DNA-binding transcriptional regulator, LysR family	297
651496808	362	67.4	1	362	1	355	0.0e+00	598	COG2933	23S rRNA C2498 (ribose-2'-O)-methylase RlmM	358
651496810	504	46.86	6	491	4	492	1.0e-91	330	COG0591	Na+/proline symporter	493
651496811	491	48.67	5	491	3	483	0.0e+00	519	COG1530	Ribonuclease G or E	487
651496813	465	33.7	1	450	4	444	1.0e-66	247	COG0534	Na+-driven multidrug efflux pump	455
651496814	227	48.69	24	214	1	188	6.0e-69	253	COG0307	Riboflavin synthase alpha chain	204
651496818	108	67.59	1	108	1	108	5.0e-39	152	COG3512	CRISPR/Cas system-associated protein Cas2, endoribonuclease	116
651496819	305	24.07	1	305	2	324	1.0e-45	177	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
651496820	1054	46.34	5	1054	2	1087	0.0e+00	1136	COG3513	CRISPR/Cas system Type II  associated protein, contains McrA/HNH and RuvC-like nuclease domains	1088
651496821	201	23.38	1	201	8	205	1.0e-30	126	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
651496822	97	52.69	4	96	1	92	1.0e-26	111	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
651496823	264	53.26	1	261	2	262	6.0e-97	347	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
651496824	296	66.55	1	289	1	290	5.0e-127	447	COG0777	Acetyl-CoA carboxylase beta subunit	294
651496825	438	40.86	7	438	1	422	1.0e-120	426	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
651496826	294	51.35	3	294	1	294	1.0e-101	363	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
651496827	155	49.33	5	151	3	150	2.0e-40	158	COG1438	Arginine repressor	150
651496828	311	37.89	1	310	1	312	2.0e-72	266	COG0039	Malate/lactate dehydrogenase	313
651496830	315	61.08	1	315	2	314	2.0e-121	429	COG0462	Phosphoribosylpyrophosphate synthetase	314
651496831	311	52.63	23	294	5	289	7.0e-92	330	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
651496832	231	39.9	24	229	3	203	4.0e-59	221	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
651496833	414	35.78	1	400	23	412	2.0e-83	303	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
651496834	208	45.1	7	208	1	204	3.0e-56	211	COG3103	Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family	205
651496836	226	40.36	4	226	1	217	1.0e-53	203	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
651496837	340	30.23	1	336	1	354	8.0e-80	290	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
651496838	459	60.7	1	458	1	455	0.0e+00	685	COG1066	Predicted ATP-dependent serine protease	456
651496839	159	48	9	158	6	154	4.0e-35	140	COG1522	DNA-binding transcriptional regulator, Lrp family	154
651496840	929	30.06	14	924	10	853	0.0e+00	549	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
651496841	208	42.86	1	204	4	211	1.0e-40	159	COG2834	Outer membrane lipoprotein-sorting protein	211
651496842	446	61.36	4	442	1	436	0.0e+00	637	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
651496843	376	46.24	17	376	2	363	2.0e-84	306	COG0687	Spermidine/putrescine-binding periplasmic protein	363
651496844	256	43.87	2	253	9	261	6.0e-60	224	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
651496845	286	48.24	1	282	1	284	7.0e-66	243	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
651496846	400	50.55	34	396	1	352	3.0e-120	425	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
651496847	411	43.73	7	406	5	408	2.0e-115	409	COG2195	Di- or tripeptidase	414
651496848	209	31.51	1	209	12	248	3.0e-33	134	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
651496849	186	50	1	186	1	185	2.0e-57	215	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
651496851	689	33.33	129	567	1	400	4.0e-90	326	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
651496852	215	51.44	14	215	1	208	7.0e-56	210	COG3109	sRNA-binding protein	208
651496853	394	48.34	2	392	29	411	2.0e-127	449	COG2995	Uncharacterized paraquat-inducible protein A	418
651496854	885	42.51	11	580	2	553	0.0e+00	603	COG3008	Paraquat-inducible protein B	553
651496855	181	51.46	4	174	3	170	2.0e-58	218	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
651496856	311	56.93	3	203	1	202	2.0e-69	256	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
651496858	344	42.49	1	343	8	354	1.0e-93	336	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
651496860	192	38.61	1	192	1	189	5.0e-43	167	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
651496861	569	26.42	23	334	18	323	9.0e-14	72.3	COG1479	Uncharacterized conserved protein, contains ParB-like and HNH nuclease domains	409
651496862	178	56.98	1	178	1	178	4.0e-80	290	COG3101	Elongation factor P hydroxylase (EF-P beta-lysylation pathway)	180
651496863	360	68.78	1	358	1	362	0.0e+00	571	COG0216	Protein chain release factor A	363
651496864	292	44.56	1	292	1	278	7.0e-74	270	COG2890	Methylase of polypeptide chain release factors	280
651496865	267	42.21	1	258	2	264	1.0e-65	243	COG2912	Regulator of sirC expression, contains transglutaminase-like and TPR domains	269
651496866	284	64.41	2	282	1	279	0.0e+00	484	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
651496867	315	39.43	1	310	1	313	6.0e-86	311	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
651496868	393	39.13	1	393	1	408	2.0e-88	319	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
651496869	430	43.15	5	430	3	447	0.0e+00	542	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
651496870	380	42.19	1	380	4	384	5.0e-119	421	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
651496871	215	79.91	1	214	1	214	2.0e-103	368	COG2830	Uncharacterized protein	214
651496873	213	43.46	1	188	1	187	1.0e-57	215	COG0132	Dethiobiotin synthetase	223
651496874	227	49.1	5	225	1	222	2.0e-78	285	COG1136	ABC-type lipoprotein export system, ATPase component	226
651496875	416	41.87	1	415	3	407	2.0e-106	380	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
651496876	136	45.99	2	134	1	136	1.0e-37	148	COG3105	Uncharacterized membrane-anchored protein YhcB, DUF1043 family	138
651496877	149	28.69	33	149	7	128	4.0e-28	117	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
651496880	669	38.49	1	251	3	252	5.0e-80	292	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
651496881	406	48.91	1	405	2	412	6.0e-124	437	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
651496882	574	49.38	3	565	1	550	0.0e+00	674	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
651496883	163	56.17	1	162	3	163	3.0e-49	187	COG0440	Acetolactate synthase, small subunit	163
651496885	221	40.54	1	221	4	217	4.0e-47	181	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
651496886	432	63.11	2	431	1	430	0.0e+00	673	COG0104	Adenylosuccinate synthase	430
651496887	450	37.83	4	450	3	446	6.0e-113	401	COG0527	Aspartokinase	447
651496888	233	51.58	12	229	4	224	2.0e-74	272	COG2949	Uncharacterized periplasmic protein SanA, affects membrane permeability for vancomycin	235
651496889	361	51.67	1	358	12	367	0.0e+00	467	COG2021	Homoserine acetyltransferase	368
651496890	184	27.23	1	184	3	204	3.0e-16	78.5	COG0778	Nitroreductase	207
651496891	620	38.41	270	544	4	276	2.0e-62	233	COG0616	Periplasmic serine protease, ClpP class	317
651496892	267	57.2	1	264	2	265	3.0e-113	401	COG4167	ABC-type antimicrobial peptide transport system, ATPase component	267
651496893	351	67.27	1	330	1	330	0.0e+00	597	COG4170	ABC-type antimicrobial peptide transport system, ATPase component	330
651496894	295	51.86	1	295	2	296	2.0e-115	409	COG4171	ABC-type antimicrobial peptide transport system, permease component	296
651496895	321	46.11	1	321	1	320	3.0e-114	405	COG4168	ABC-type antimicrobial peptide transport system, permease component	321
651496896	566	24.07	1	566	4	562	7.0e-69	255	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
651496897	469	58.12	1	468	1	466	0.0e+00	706	COG3106	Predicted ATPase, YcjX-like family	467
651496898	186	54.55	2	186	1	179	3.0e-50	191	COG2032	Cu/Zn superoxide dismutase	179
651496900	92	37.14	24	92	2	71	4.0e-09	53.1	COG2608	Copper chaperone CopZ	71
651496902	368	20.42	32	356	15	318	2.0e-30	126	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
651496903	355	40.06	3	351	4	350	7.0e-104	370	COG3768	Uncharacterized membrane protein YcjF, UPF0283 family	350
651496904	364	64.44	127	364	1	239	3.0e-102	365	COG1186	Protein chain release factor B	239
651496906	228	26.07	6	228	13	244	2.0e-27	116	COG1651	Protein-disulfide isomerase	244
651496907	575	41.49	31	550	1	491	1.0e-115	410	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
651496909	229	51.08	1	229	3	233	7.0e-62	230	COG0775	Nucleoside phosphorylase	234
651496911	226	58.82	2	221	3	220	2.0e-79	288	COG0283	Cytidylate kinase	222
651496912	549	59.01	1	542	1	541	0.0e+00	604	COG0539	Ribosomal protein S1	541
651496913	94	52.75	1	91	2	91	3.0e-26	110	COG0776	Bacterial nucleoid DNA-binding protein	94
651496914	107	54.17	12	107	1	96	1.0e-27	114	COG3771	Uncharacterized membrane protein YciS, DUF1049 family	97
651496915	392	54.1	1	389	1	382	0.0e+00	519	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
651496916	230	51.74	1	230	10	235	8.0e-76	276	COG0284	Orotidine-5'-phosphate decarboxylase	240
651496917	112	56.73	12	112	1	103	1.0e-23	101	COG0023	Translation initiation factor 1 (eIF-1/SUI1)	104
651496918	118	35.59	1	111	5	122	2.0e-14	71.1	COG3094	Uncharacterized membrane protein SirB2	129
651496919	556	48.8	4	536	1	528	0.0e+00	588	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
651496920	210	45.63	6	209	10	213	7.0e-56	210	COG3683	ABC-type uncharacterized transport system, periplasmic component	213
651496921	325	39.86	20	315	22	303	9.0e-61	227	COG2215	ABC-type nickel/cobalt efflux system, permease component RcnA	303
651496922	220	28.44	6	220	2	206	3.0e-34	138	COG0778	Nitroreductase	207
651496923	247	25.86	14	245	1	217	7.0e-25	107	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
651496924	318	27.27	21	318	28	318	3.0e-47	182	COG5039	Exopolysaccharide biosynthesis protein EpsI, predicted pyruvyl transferase	339
651496925	512	16.89	4	436	17	450	1.0e-06	48.3	COG0534	Na+-driven multidrug efflux pump	455
651496931	589	24.36	92	551	17	470	1.0e-58	221	COG3378	Phage- or plasmid-associated DNA primase	517
651496932	406	20.9	93	394	1	303	6.0e-09	55.7	COG0582	Integrase	309
651496934	465	49.89	1	464	13	477	0.0e+00	554	COG0469	Pyruvate kinase	477
651496935	468	48.42	18	459	1	434	0.0e+00	534	COG0305	Replicative DNA helicase	435
651496936	360	48.9	3	360	2	360	1.0e-121	430	COG0787	Alanine racemase	360
651496937	549	53.96	49	539	4	446	0.0e+00	563	COG0166	Glucose-6-phosphate isomerase	446
651496938	414	18.16	34	409	10	383	7.0e-11	62.1	COG2814	Predicted arabinose efflux permease, MFS family	394
651496940	484	37.95	9	470	5	471	3.0e-111	395	COG1621	Sucrose-6-phosphate hydrolase SacC, GH32 family	486
651496941	203	23.38	1	193	1	195	2.0e-16	79.1	COG0625	Glutathione S-transferase	211
651496942	308	34.78	4	308	1	309	2.0e-55	210	COG0524	Sugar or nucleoside kinase, ribokinase family	311
651496943	395	46.53	1	394	1	400	9.0e-122	430	COG0162	Tyrosyl-tRNA synthetase	401
651496944	238	50.84	1	237	2	235	7.0e-84	303	COG1489	DNA-binding protein, stimulates sugar fermentation	235
651496945	248	27.42	2	246	4	234	1.0e-18	86.6	COG2859	Uncharacterized protein	237
651496946	220	33.63	8	220	11	233	1.0e-26	113	COG0670	Integral membrane protein, interacts with FtsH	233
651496948	949	61.83	21	949	1	906	0.0e+00	1413	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
651496949	408	53.53	1	407	1	404	1.0e-120	426	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
651496950	392	26.18	2	381	16	408	1.0e-42	167	COG1457	Purine-cytosine permease or related protein	442
651496951	388	62.05	1	388	1	387	0.0e+00	531	COG0045	Succinyl-CoA synthetase, beta subunit	387
651496952	289	72.76	1	289	1	290	1.0e-121	429	COG0074	Succinyl-CoA synthetase, alpha subunit	293
651496953	207	46.6	2	206	1	204	1.0e-62	232	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
651496954	336	46.03	53	299	1	248	9.0e-72	264	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
651496955	327	27.67	5	301	1	294	2.0e-39	156	COG0583	DNA-binding transcriptional regulator, LysR family	297
651496957	314	41.24	23	311	1	280	2.0e-63	236	COG2890	Methylase of polypeptide chain release factors	280
651496958	169	46.24	4	169	9	180	2.0e-47	182	COG2840	DNA-nicking endonuclease, Smr domain	184
651496959	577	43.59	1	577	1	577	0.0e+00	636	COG0018	Arginyl-tRNA synthetase	577
651496960	189	43.33	9	188	11	183	3.0e-54	204	COG3102	Uncharacterized conserved protein YecM, predicted metalloenzyme	185
651496962	154	55.41	1	147	1	148	8.0e-39	153	COG3133	Outer membrane lipoprotein SlyB	154
651496963	275	55.71	1	273	1	271	4.0e-89	321	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
651496964	286	60.42	1	96	4	99	2.0e-39	156	COG3615	Uncharacterized protein/domain, possibly involved in tellurite resistance	99
651496965	682	42.6	2	547	1	558	0.0e+00	675	COG0143	Methionyl-tRNA synthetase	558
651496966	370	42.45	49	323	3	265	8.0e-62	231	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
651496967	240	37.32	36	240	3	203	6.0e-39	154	COG0406	Broad specificity phosphatase PhoE	208
651496968	455	27.17	14	455	1	448	7.0e-66	245	COG1538	Outer membrane protein TolC	457
651496969	643	54.42	3	226	1	226	2.0e-79	290	COG1136	ABC-type lipoprotein export system, ATPase component	226
651496970	393	25.97	7	390	16	369	1.0e-31	131	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
651496971	557	36.15	28	536	1	472	1.0e-115	410	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
651496972	146	54.86	1	143	5	146	1.0e-52	198	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
651496974	729	60.03	100	727	1	628	0.0e+00	841	COG0296	1,4-alpha-glucan branching enzyme	628
651496975	672	49.63	1	643	8	669	0.0e+00	747	COG1523	Pullulanase/glycogen debranching enzyme	697
651496976	440	49.04	18	432	2	393	0.0e+00	521	COG0448	ADP-glucose pyrophosphorylase	393
651496977	479	47.54	1	478	1	480	0.0e+00	522	COG0297	Glycogen synthase	487
651496978	821	49.69	14	816	1	750	0.0e+00	901	COG0058	Glucan phosphorylase	750
651496979	157	61.44	1	153	1	152	7.0e-52	196	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
651496980	145	47.22	9	145	5	148	3.0e-36	143	COG0781	Transcription termination factor NusB	151
651496981	326	46.46	1	323	1	317	1.0e-96	346	COG0611	Thiamine monophosphate kinase	317
651496982	164	41.14	2	157	4	159	8.0e-34	136	COG1267	Phosphatidylglycerophosphatase A	160
651496983	208	29.27	1	203	6	208	8.0e-23	100	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
651496984	270	56.93	1	267	1	266	6.0e-99	353	COG0289	Dihydrodipicolinate reductase	266
651496985	82	33.33	1	81	5	94	1.0e-12	65.1	COG0633	Ferredoxin	102
651496987	123	40.77	2	123	1	128	1.0e-27	115	COG3111	Predicted periplasmic protein YdeI with OB-fold, BOF family	128
651496988	240	42.92	19	234	1	225	6.0e-59	220	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
651496989	451	31.74	155	442	35	322	3.0e-34	139	COG0642	Signal transduction histidine kinase	336
651496994	151	49.01	1	151	3	153	2.0e-48	184	COG0779	Ribosome maturation factor RimP	153
651496995	495	46.94	157	351	1	190	3.0e-48	186	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
651496996	839	65.09	336	839	1	507	0.0e+00	690	COG0532	Translation initiation factor IF-2, a GTPase	509
651496997	128	49.12	7	120	6	118	1.0e-29	121	COG0858	Ribosome-binding factor A	118
651496998	304	40.53	5	302	5	271	1.0e-74	273	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
651496999	374	29.33	97	353	2	279	1.0e-57	217	COG0287	Prephenate dehydrogenase	279
651497000	279	61.76	1	135	1	136	3.0e-53	202	COG2904	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, N-terminal domain	137
651497001	261	65.9	1	261	1	256	1.0e-110	392	COG5595	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	256
651497002	124	37.9	1	124	15	138	7.0e-33	132	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
651497003	400	45.81	1	397	1	405	3.0e-114	405	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
651497004	171	30.72	12	163	23	188	9.0e-29	119	COG1525	Endonuclease YncB, thermonuclease family	192
651497005	138	40.62	3	130	1	128	4.0e-21	93.7	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
651497006	230	42.92	1	226	3	228	2.0e-58	218	COG1346	Putative effector of murein hydrolase	230
651497007	450	40.27	1	450	9	408	7.0e-122	430	COG0232	dGTP triphosphohydrolase	412
651497008	647	45.19	1	533	1	530	0.0e+00	554	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
651497009	456	44.25	5	455	2	432	4.0e-111	395	COG0733	Na+-dependent transporter, SNF family	439
651497010	211	58.85	1	209	1	209	2.0e-87	314	COG0177	Endonuclease III	211
651497011	236	74.27	31	236	5	210	1.0e-86	312	COG4660	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfE subunit	212
651497012	208	56.7	5	197	2	195	9.0e-70	256	COG4659	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit	195
651497013	360	57.46	4	357	3	338	2.0e-110	392	COG4658	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfD subunit	338
651497014	778	57.12	11	544	1	527	0.0e+00	666	COG4656	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfC subunit	529
651497015	194	56.99	1	189	5	197	1.0e-63	235	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
651497016	192	79.17	1	192	1	192	1.0e-68	252	COG4657	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfA subunit	193
651497017	717	28.29	1	711	3	666	4.0e-120	425	COG1289	Uncharacterized membrane protein YccC	674
651497018	218	41.47	2	218	1	216	6.0e-58	217	COG3110	Uncharacterized conserved protein YccT, UPF0319 family	216
651497019	89	52.87	1	86	4	90	1.0e-22	98	COG1254	Acylphosphatase	92
651497020	106	49.52	1	105	3	106	1.0e-26	111	COG3098	Uncharacterized conserved protein YqcC, DUF446 family	109
651497021	238	37	2	225	78	289	3.0e-53	202	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
651497023	69	49.25	1	67	1	67	5.0e-21	92.9	COG1278	Cold shock protein, CspA family	67
651497024	149	60.4	1	149	1	149	7.0e-49	186	COG3120	Macrodomain Ter protein organizer, MatP/YcbG family	149
651497025	600	38.05	32	593	71	646	0.0e+00	491	COG1067	Predicted ATP-dependent protease	647
651497026	177	35.44	18	173	1	147	3.0e-36	144	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
651497027	159	56.33	1	158	1	155	3.0e-47	181	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
651497028	317	25.53	5	313	2	334	4.0e-51	195	COG0136	Aspartate-semialdehyde dehydrogenase	334
651497029	435	55.5	1	435	1	436	3.0e-120	425	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
651497030	118	32.03	2	118	1	126	7.0e-23	99.2	COG1553	Sulfur relay (sulfurtransferase) complex TusBCD TusD component, DsrE family	126
651497031	1031	36.41	27	1026	2	962	0.0e+00	636	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
651497034	378	19.95	10	374	5	390	2.0e-14	73.9	COG0732	Restriction endonuclease S subunit	391
651497035	514	37.07	5	514	1	486	2.0e-102	366	COG0286	Type I restriction-modification system, DNA methylase subunit	489
651497036	1213	31.83	1	1185	1	1139	0.0e+00	680	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
651497037	644	26.67	1	641	32	694	4.0e-104	372	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
651497038	215	55.81	1	215	1	215	1.0e-79	289	COG2999	Glutaredoxin 2	215
651497040	256	39.18	1	241	7	250	7.0e-54	203	COG2966	Uncharacterized membrane protein YjjP, DUF1212 family	250
651497041	153	51.61	1	153	1	155	8.0e-30	123	COG3610	Uncharacterized membrane protein YjjB, DUF3815 family	156
651497042	91	32.14	9	91	7	79	7.0e-04	35.7	COG5645	Uncharacterized conserved protein YceK	80
651497043	418	26.38	129	342	16	249	2.0e-15	77.4	COG0790	TPR repeat	292
651497044	376	25.51	126	352	15	257	3.0e-13	69.7	COG0790	TPR repeat	292
651497045	184	46.15	25	180	1	156	1.0e-46	178	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
651497046	532	28.99	13	529	5	550	1.0e-68	254	COG0747	ABC-type transport system, periplasmic component	556
651497047	317	42.04	4	315	1	314	1.0e-74	273	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
651497048	658	49.32	339	619	1	286	1.0e-98	354	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
651497051	186	44.25	12	185	35	205	3.0e-45	174	COG1859	RNA:NAD 2'-phosphotransferase, TPT1/KptA family	211
651497052	291	38.1	52	168	9	132	2.0e-32	133	COG0295	Cytidine deaminase	134
651497053	776	61.75	443	774	1	330	9.0e-127	448	COG0620	Methionine synthase II (cobalamin-independent)	330
651497054	794	36.48	8	794	19	699	0.0e+00	533	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
651497055	340	25.38	1	305	1	319	4.0e-33	135	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
651497058	69	62.32	1	69	1	69	1.0e-14	71.5	COG3585	Molybdopterin-binding protein	69
651497059	344	27.78	1	309	1	319	2.0e-38	153	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
651497060	262	37.84	1	257	2	253	9.0e-64	236	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
651497061	328	43.98	1	325	1	330	1.0e-51	197	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
651497063	1012	52.14	1	1012	1	1013	0.0e+00	1310	COG4457	Uncharacterized protein	1014
651497067	248	33.18	10	222	1	208	5.0e-45	174	COG1136	ABC-type lipoprotein export system, ATPase component	226
651497068	402	17.04	20	402	23	408	1.0e-11	64.5	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
651497069	525	20.65	76	300	59	310	2.0e-15	77.5	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
651497074	109	69.72	1	109	3	111	7.0e-47	178	COG2920	Sulfur relay (sulfurtransferase) protein, DsrC/TusE family	111
651497075	309	32.75	16	297	1	280	1.0e-54	207	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
651497077	166	62.96	1	162	1	162	1.0e-58	218	COG1528	Ferritin	167
651497078	161	56.52	1	161	1	161	4.0e-59	220	COG1528	Ferritin	167
651497079	473	63.98	1	472	5	475	0.0e+00	790	COG2925	Exonuclease I	475
651497081	1505	69.09	37	1505	1	1471	0.0e+00	2198	COG3096	Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Escherichia coli str. K-12 substr. MG1655	1480
651497082	250	65.71	1	245	1	236	1.0e-103	369	COG3095	Chromosome condensin MukBEF, MukE localization factor	238
651497083	444	68.92	1	444	1	440	0.0e+00	744	COG3006	Chromosome condensin MukBEF complex, kleisin-like MukF subunit	440
651497085	257	34.95	34	238	7	212	3.0e-40	159	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
651497086	307	25	154	304	3	152	7.0e-14	71.5	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
651497087	277	37.22	1	263	1	264	4.0e-69	254	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
651497090	268	28.87	31	268	7	229	1.0e-16	80.8	COG2801	Transposase InsO and inactivated derivatives	232
651497091	186	31.89	1	181	15	198	3.0e-37	148	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
651497092	868	47.76	3	597	1	567	0.0e+00	668	COG0550	DNA topoisomerase IA	570
651497093	299	30.03	4	290	3	289	6.0e-41	161	COG0583	DNA-binding transcriptional regulator, LysR family	297
651497094	275	47.86	2	256	1	254	5.0e-67	248	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
651497095	339	44.11	50	339	5	289	3.0e-87	315	COG0167	Dihydroorotate dehydrogenase	310
651497096	869	40.16	1	863	7	859	0.0e+00	710	COG0308	Aminopeptidase N	859
651497097	164	61.73	3	164	1	160	8.0e-62	229	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
651497098	366	39.63	11	361	1	375	1.0e-120	426	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
651497100	396	62.88	1	396	1	396	0.0e+00	640	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
651497102	613	23.96	17	458	34	471	1.0e-38	154	COG2189	Adenine specific DNA methylase Mod	590
651497103	150	48.32	1	149	1	149	6.0e-48	183	COG0314	Molybdopterin synthase catalytic subunit	149
651497104	81	44.05	1	81	1	84	6.0e-17	78.8	COG1977	Molybdopterin converting factor, small subunit	84
651497105	186	68.35	27	184	1	157	2.0e-64	238	COG0315	Molybdenum cofactor biosynthesis enzyme	157
651497106	337	49.23	13	337	1	322	2.0e-116	412	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
651497107	314	38.06	13	312	4	309	9.0e-67	247	COG0391	Archaeal 2-phospho-L-lactate transferase/Bacterial gluconeogenesis factor, CofD/UPF0052 family	323
651497108	483	41.45	1	384	2	383	4.0e-106	378	COG0301	Adenylyl- and sulfurtransferase ThiI, participates in tRNA 4-thiouridine and thiamine biosynthesis	383
651497109	80	50	1	80	1	80	2.0e-11	60.3	COG1722	Exonuclease VII small subunit	81
651497110	297	41.34	8	297	6	322	1.0e-66	246	COG0142	Geranylgeranyl pyrophosphate synthase	322
651497111	617	63.74	3	617	1	624	0.0e+00	975	COG1154	Deoxyxylulose-5-phosphate synthase	627
651497112	117	81.2	1	117	1	117	1.0e-39	155	COG0292	Ribosomal protein L20	118
651497113	65	61.54	1	65	1	65	4.0e-10	56.4	COG0291	Ribosomal protein L35	65
651497114	450	25.19	203	450	55	279	2.0e-14	73.9	COG0790	TPR repeat	292
651497115	154	68.83	1	154	23	175	4.0e-58	217	COG0290	Translation initiation factor IF-3	176
651497116	272	39.93	5	267	9	280	3.0e-83	301	COG0676	D-hexose-6-phosphate mutarotase	287
651497117	643	54.77	34	640	1	588	0.0e+00	806	COG0441	Threonyl-tRNA synthetase	589
651497118	193	47.26	1	190	2	202	9.0e-57	213	COG1182	FMN-dependent NADH-azoreductase	202
651497119	516	36.35	9	516	2	462	1.0e-129	457	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
651497120	194	48.97	1	190	1	191	3.0e-68	251	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
651497122	333	51.04	1	333	2	335	6.0e-111	394	COG0547	Anthranilate phosphoribosyltransferase	338
651497123	478	51.35	16	272	1	254	8.0e-87	314	COG0134	Indole-3-glycerol phosphate synthase	254
651497124	252	57.68	3	242	7	246	4.0e-89	320	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
651497125	398	67.34	2	396	1	394	0.0e+00	694	COG0133	Tryptophan synthase beta chain	396
651497126	268	45.15	1	268	1	264	1.0e-85	309	COG0159	Tryptophan synthase alpha chain	265
651497128	148	50.97	1	148	1	155	9.0e-57	212	COG2969	Stringent starvation protein B	155
651497129	212	32.54	11	205	1	206	3.0e-33	135	COG0625	Glutathione S-transferase	211
651497130	130	66.92	1	130	1	130	1.0e-47	181	COG0103	Ribosomal protein S9	130
651497131	142	64.34	1	142	1	143	3.0e-56	210	COG0102	Ribosomal protein L13	148
651497132	296	47.78	7	292	1	291	7.0e-83	300	COG0685	5,10-methylenetetrahydrofolate reductase	291
651497134	110	44.68	14	107	1	94	4.0e-24	103	COG0776	Bacterial nucleoid DNA-binding protein	94
651497135	796	48.63	143	795	1	650	0.0e+00	711	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
651497136	329	54.49	1	327	3	335	3.0e-125	441	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
651497137	287	50.7	1	285	1	284	6.0e-101	360	COG3001	Fructosamine-3-kinase	286
651497141	467	47.66	1	467	1	435	0.0e+00	547	COG0017	Aspartyl/asparaginyl-tRNA synthetase	435
651497142	230	48.31	1	203	1	207	6.0e-62	230	COG0288	Carbonic anhydrase	207
651497143	246	41.67	3	239	2	223	5.0e-63	234	COG0132	Dethiobiotin synthetase	223
651497144	88	53.41	1	88	11	98	3.0e-27	113	COG3100	Uncharacterized conserved protein YcgL, UPF0745 family	103
651497146	163	33.14	1	158	2	163	2.0e-34	138	COG2062	Phosphohistidine phosphatase SixA	163
651497147	444	47.16	1	443	4	459	2.0e-122	433	COG1109	Phosphomannomutase	464
651497148	275	50.76	15	275	8	267	2.0e-81	296	COG0294	Dihydropteroate synthase	274
651497149	635	58.33	9	603	1	596	0.0e+00	779	COG0465	ATP-dependent Zn proteases	596
651497150	210	58.62	7	209	1	203	7.0e-73	266	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
651497151	99	56.25	4	98	2	97	3.0e-28	116	COG1534	RNA-binding protein YhbY	97
651497152	158	53.59	6	158	1	151	5.0e-44	170	COG0782	Transcription elongation factor, GreA/GreB family	151
651497153	479	41.26	8	479	3	470	0.0e+00	471	COG2027	D-alanyl-D-alanine carboxypeptidase	470
651497154	505	51.53	1	486	4	470	0.0e+00	627	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
651497155	163	44.79	1	162	3	165	2.0e-28	118	COG1286	Uncharacterized membrane protein, required for colicin V production	182
651497156	148	50.68	3	148	8	149	1.0e-47	182	COG3092	Uncharacterized membrane protein YfbV, UPF0208 family	149
651497157	401	54.23	3	401	1	394	0.0e+00	551	COG0282	Acetate kinase	396
651497158	483	56.44	162	482	1	325	1.0e-106	380	COG0280	Phosphotransacetylase	327
651497159	383	42.43	14	381	1	360	6.0e-92	331	COG0349	Ribonuclease D	361
651497160	562	35.78	14	561	2	531	0.0e+00	473	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
651497161	180	29.41	1	179	5	188	2.0e-43	168	COG3065	Starvation-inducible outer membrane lipoprotein	191
651497162	236	40.09	5	231	2	219	4.0e-47	181	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
651497163	640	41.96	9	638	1	651	0.0e+00	538	COG1199	Rad3-related DNA helicase	654
651497167	354	29.69	1	310	6	315	3.0e-42	166	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
651497168	437	64.49	11	437	4	430	0.0e+00	654	COG0001	Glutamate-1-semialdehyde aminotransferase	432
651497169	861	47.98	1	861	1	861	0.0e+00	1016	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
651497170	267	53.91	1	254	1	255	3.0e-96	344	COG0024	Methionine aminopeptidase	255
651497171	115	55.45	6	115	1	110	1.0e-39	154	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
651497172	132	50.42	16	132	1	119	8.0e-39	152	COG3112	Uncharacterized protein YacL, UPF0231 family	121
651497173	799	35.36	87	771	5	659	0.0e+00	554	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
651497174	634	38.95	272	628	32	383	5.0e-75	276	COG0672	High-affinity Fe2+/Pb2+ permease	383
651497175	173	70.11	1	171	3	176	9.0e-73	266	COG3470	Uncharacterized protein probably involved in high-affinity Fe2+ transport	179
651497176	464	42.62	1	413	1	405	3.0e-115	408	COG4393	Uncharacterized membrane protein	405
651497177	446	21.21	16	445	3	419	1.0e-27	117	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
651497178	377	22.11	6	377	3	408	8.0e-22	98.4	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
651497179	223	49.12	5	221	1	226	3.0e-74	271	COG1136	ABC-type lipoprotein export system, ATPase component	226
651497180	159	25.68	27	158	5	150	2.0e-06	45.6	COG1225	Peroxiredoxin	157
651497181	107	29.63	1	107	1	101	6.0e-13	65.8	COG2863	Cytochrome c553	121
651497184	146	31.36	1	112	11	128	2.0e-17	81.6	COG3794	Plastocyanin	128
651497185	257	38.13	1	253	2	258	8.0e-57	213	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
651497186	349	38.92	19	348	2	332	3.0e-49	189	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
651497187	371	25.15	5	341	15	319	3.0e-35	143	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
651497188	380	38.19	35	320	63	324	3.0e-60	226	COG1858	Cytochrome c peroxidase	364
651497189	379	34.54	23	379	11	341	5.0e-75	274	COG2951	Membrane-bound lytic murein transglycosylase B	343
651497191	293	20.2	1	271	4	294	6.0e-14	71.7	COG1216	Glycosyltransferase, GT2 family	305
651497193	256	26.72	3	256	9	253	2.0e-32	132	COG3306	Glycosyltransferase involved in LPS biosynthesis, GR25 family	255
651497194	336	46.59	2	336	1	333	4.0e-99	355	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
651497195	879	54.01	4	879	5	910	0.0e+00	1187	COG2352	Phosphoenolpyruvate carboxylase	910
651497196	112	59.26	6	112	1	108	6.0e-35	139	COG3099	Uncharacterized conserved protein YciU, UPF0263 family	108
651497197	337	50	5	337	3	339	4.0e-95	341	COG0309	Hydrogenase maturation factor	339
651497198	370	57.14	1	370	1	363	0.0e+00	489	COG0409	Hydrogenase maturation factor	364
651497199	268	46.34	66	266	2	199	4.0e-63	234	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
651497200	113	46.02	1	113	1	113	1.0e-24	104	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
651497201	137	34.91	1	105	1	106	4.0e-17	80.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
651497202	227	25.66	1	227	1	264	1.0e-26	113	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
651497204	203	31.68	1	196	1	199	9.0e-22	96.9	COG0310	ABC-type Co2+ transport system, permease component	204
651497205	214	29.95	9	203	18	214	3.0e-10	58.8	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
651497206	213	41.04	1	207	1	212	1.0e-48	186	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
651497209	152	32.17	5	138	5	145	2.0e-19	88.1	COG0680	Ni,Fe-hydrogenase maturation factor	160
651497211	258	60	29	173	1	145	1.0e-58	219	COG3260	Ni,Fe-hydrogenase III small subunit	148
651497212	215	34.29	1	135	19	157	2.0e-26	112	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
651497213	576	57.11	181	558	4	381	0.0e+00	480	COG3261	Ni,Fe-hydrogenase III large subunit	382
651497214	512	33.13	5	493	9	490	9.0e-50	191	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
651497215	212	38.97	2	212	6	218	2.0e-31	128	COG4237	Hydrogenase-4 membrane subunit HyfE	218
651497216	481	37.65	5	477	1	473	6.0e-78	285	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
651497217	320	41.69	14	318	6	309	7.0e-53	201	COG0650	Formate hydrogenlyase subunit 4	309
651497218	673	32.87	6	498	3	480	5.0e-67	249	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
651497219	214	40.1	16	205	1	155	6.0e-36	144	COG1142	Fe-S-cluster-containing hydrogenase component 2	165
651497220	91	58.02	1	81	1	77	6.0e-20	88.8	COG0298	Hydrogenase maturation factor	82
651497221	755	48.82	5	751	2	745	0.0e+00	836	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
651497222	306	48.16	5	303	1	297	2.0e-69	256	COG2431	Uncharacterized membrane protein YbjE, DUF340 family	297
651497223	363	64.86	11	360	2	351	0.0e+00	592	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
651497225	463	46.22	6	374	2	345	4.0e-79	289	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
651497226	678	70.06	7	674	2	659	0.0e+00	1124	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
651497230	267	47.96	1	267	1	260	7.0e-89	320	COG0708	Exonuclease III	261
651497231	436	31.09	12	435	1	421	1.0e-53	204	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
651497232	225	36.7	1	206	76	283	2.0e-46	179	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
651497233	486	34.73	47	486	1	438	2.0e-74	273	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
651497234	506	35.73	6	504	1	485	5.0e-75	275	COG1757	Na+/H+ antiporter NhaC	485
651497235	134	42.19	7	134	1	127	3.0e-21	94.3	COG2916	DNA-binding protein H-NS	128
651497236	278	51.94	2	278	5	286	9.0e-114	403	COG0788	Formyltetrahydrofolate hydrolase	287
651497237	432	46.22	1	432	2	428	0.0e+00	492	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
651497238	391	20.5	32	385	36	392	3.0e-22	99.9	COG2814	Predicted arabinose efflux permease, MFS family	394
651497239	218	44.33	27	218	4	194	3.0e-63	235	COG0302	GTP cyclohydrolase I	195
651497240	405	46.65	1	402	6	404	0.0e+00	472	COG0303	Molybdopterin biosynthesis enzyme	404
651497241	240	53.72	3	239	2	243	6.0e-68	250	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
651497243	434	25.21	162	399	1	189	3.0e-13	70.1	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
651497244	89	36	16	89	2	76	2.0e-14	70.7	COG0425	TusA-related sulfurtransferase	78
651497246	459	58.35	1	457	1	463	0.0e+00	655	COG1282	NAD/NADP transhydrogenase beta subunit	463
651497247	513	62.26	3	365	2	356	0.0e+00	464	COG3288	NAD/NADP transhydrogenase alpha subunit	356
651497248	482	39.74	17	481	2	454	4.0e-122	431	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
651497249	282	56.68	3	279	2	273	2.0e-104	371	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
651497250	573	41.85	1	572	2	604	0.0e+00	595	COG3107	Outer membrane lipoprotein LpoA, binds and activates PBP1a	604
651497251	119	46.09	5	119	1	113	6.0e-34	136	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
651497252	194	40.78	1	179	1	176	4.0e-52	197	COG0279	Phosphoheptose isomerase	176
651497253	193	49.23	1	193	2	196	8.0e-47	180	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
651497254	756	36.75	41	755	1	654	0.0e+00	618	COG0209	Ribonucleotide reductase alpha subunit	696
651497256	376	36.27	2	372	1	347	9.0e-93	334	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
651497257	502	63.76	1	502	1	501	0.0e+00	731	COG1190	Lysyl-tRNA synthetase (class II)	502
651497258	381	23.35	15	377	4	330	5.0e-58	218	COG0620	Methionine synthase II (cobalamin-independent)	330
651497259	420	30.1	1	399	4	397	2.0e-72	266	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
651497260	408	40.86	7	406	10	430	1.0e-72	267	COG1457	Purine-cytosine permease or related protein	442
651497261	397	28.54	1	396	9	416	6.0e-59	222	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
651497262	245	58	1	245	1	250	3.0e-101	361	COG1540	Lactam utilization protein B (function unknown)	252
651497263	309	48.73	2	309	1	314	6.0e-111	393	COG1984	Allophanate hydrolase subunit 2	314
651497264	213	49.53	3	212	1	214	5.0e-70	257	COG2049	Allophanate hydrolase subunit 1	223
651497265	334	63.86	1	332	1	326	0.0e+00	495	COG0158	Fructose-1,6-bisphosphatase	326
651497266	359	33.61	3	359	1	363	1.0e-66	247	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
651497267	363	36.19	1	351	2	363	3.0e-60	226	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
651497268	491	47.98	1	491	1	485	0.0e+00	562	COG0260	Leucyl aminopeptidase	485
651497269	283	29.18	58	280	73	305	3.0e-26	112	COG3021	Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily	309
651497270	224	58.11	1	222	1	220	7.0e-76	276	COG2846	Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains	221
651497271	645	25.53	4	640	6	644	1.0e-102	367	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
651497272	429	57.55	6	427	13	423	0.0e+00	567	COG0281	Malic enzyme	432
651497273	209	42.92	1	207	1	209	7.0e-64	236	COG3955	Uncharacterized protein, DUF1919 family	211
651497274	232	39	1	232	3	243	2.0e-67	249	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
651497275	399	17.55	36	394	39	388	7.0e-17	81.8	COG2814	Predicted arabinose efflux permease, MFS family	394
651497276	508	63.79	11	492	12	495	0.0e+00	745	COG0753	Catalase	496
651497277	479	51.89	13	457	4	452	0.0e+00	536	COG1115	Na+/alanine symporter	452
651497278	305	33.33	1	302	7	306	3.0e-54	205	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
651497280	246	19.72	35	239	2	218	2.0e-06	46	COG0671	Membrane-associated phospholipid phosphatase	232
651497281	215	60	2	196	1	193	3.0e-75	274	COG0807	GTP cyclohydrolase II	193
651497283	225	45.62	8	219	1	212	4.0e-73	267	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
651497285	632	48.28	1	631	2	633	0.0e+00	851	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
651497286	397	18.3	5	332	1	393	2.0e-13	70.9	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
651497287	751	42.88	1	744	1	745	0.0e+00	784	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
651497288	404	57.04	1	397	1	397	7.0e-127	447	COG0786	Na+/glutamate symporter	404
651497289	1149	56	18	1149	8	1135	0.0e+00	1519	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
651497291	614	32.63	27	582	82	695	0.0e+00	469	COG1444	tRNA(Met) C34 N-acetyltransferase TmcA	758
651497292	588	30.6	5	319	18	327	8.0e-41	162	COG0642	Signal transduction histidine kinase	336
651497294	304	43.64	79	303	3	237	2.0e-55	209	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
651497295	487	30	257	476	1	170	3.0e-35	143	COG0516	IMP dehydrogenase/GMP reductase	170
651497296	519	67.61	202	519	2	315	0.0e+00	560	COG0519	GMP synthase, PP-ATPase domain/subunit	315
651497297	310	23.55	11	310	9	311	5.0e-15	75.3	COG0679	Predicted permease	311
651497299	109	57.01	2	108	1	106	3.0e-28	116	COG1687	Branched-chain amino acid transport protein AzlD	106
651497300	241	29.83	3	239	1	238	2.0e-43	169	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
651497301	309	31.67	6	302	1	296	3.0e-37	149	COG0583	DNA-binding transcriptional regulator, LysR family	297
651497304	350	46.88	2	348	1	352	2.0e-115	409	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
651497305	685	32.6	129	670	1	531	2.0e-96	347	COG1178	ABC-type Fe3+ transport system, permease component	540
651497306	345	44.88	48	344	4	299	1.0e-73	270	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
651497307	346	44.95	45	345	1	299	1.0e-70	260	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
651497308	213	55.87	1	213	3	211	1.0e-73	269	COG0572	Uridine kinase	218
651497309	193	43.01	1	192	1	183	3.0e-50	191	COG0717	Deoxycytidine triphosphate deaminase	183
651497311	392	35.53	1	392	1	394	2.0e-70	260	COG2814	Predicted arabinose efflux permease, MFS family	394
651497312	327	52.43	10	318	3	266	2.0e-106	379	COG4608	ABC-type oligopeptide transport system, ATPase component	309
651497313	327	57.86	3	317	1	315	1.0e-122	433	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
651497314	298	50.69	10	298	4	288	8.0e-75	274	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
651497315	334	49.25	1	334	1	316	3.0e-92	332	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
651497316	725	46.46	8	656	1	655	0.0e+00	616	COG0210	Superfamily I DNA or RNA helicase	655
651497317	348	37.21	44	339	1	296	6.0e-57	214	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
651497318	269	47.98	22	267	19	265	4.0e-85	307	COG1526	Formate dehydrogenase assembly factor FdhD	266
651497321	311	45.45	25	244	1	202	8.0e-60	224	COG0437	Fe-S-cluster-containing dehydrogenase component	203
651497322	238	53.21	6	221	1	217	2.0e-63	235	COG2864	Cytochrome b subunit of formate dehydrogenase	218
651497323	302	56.63	1	301	1	308	9.0e-113	400	COG3058	Formate dehydrogenase maturation protein FdhE	308
651497324	146	28.92	1	146	11	176	2.0e-18	84.7	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
651497325	134	37.31	1	133	1	127	2.0e-30	124	COG3050	DNA polymerase III, psi subunit	133
651497327	330	41.75	39	329	4	298	7.0e-91	327	COG2813	16S rRNA G1207 methylase RsmC	300
651497328	165	36.69	1	163	23	171	1.0e-33	136	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
651497329	117	62.39	1	109	1	109	9.0e-27	112	COG2926	Uncharacterized conserved protein YeeX, DUF496 family	109
651497330	360	56.04	1	360	3	365	0.0e+00	496	COG1932	Phosphoserine aminotransferase	365
651497331	369	41.64	7	367	2	356	7.0e-96	344	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
651497332	165	62.66	1	158	1	158	1.0e-62	232	COG2077	Peroxiredoxin	158
651497333	261	26.82	1	259	2	261	5.0e-48	184	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
651497334	154	50.33	4	153	1	153	4.0e-42	163	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
651497335	362	48.27	1	346	13	348	7.0e-115	407	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
651497336	757	30.77	1	477	3	518	9.0e-125	441	COG2918	Gamma-glutamylcysteine synthetase	518
651497337	332	28.66	39	332	1	299	8.0e-38	151	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
651497338	506	33.02	1	504	4	532	5.0e-83	302	COG1178	ABC-type Fe3+ transport system, permease component	540
651497339	350	41.5	1	341	2	342	7.0e-97	347	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
651497340	239	50.21	1	236	7	245	1.0e-55	210	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
651497341	608	51.89	1	606	2	581	0.0e+00	675	COG0322	Excinuclease UvrABC, nuclease subunit	581
651497342	254	61.66	2	254	1	243	5.0e-103	367	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
651497343	59	52.73	5	59	1	55	1.0e-10	58.3	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
651497344	337	49.85	12	334	6	333	1.0e-107	383	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
651497345	582	40.77	9	582	1	567	0.0e+00	486	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
651497346	800	38.93	540	790	41	293	6.0e-65	242	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
651497347	145	54.17	26	145	1	120	2.0e-31	128	COG1734	RNA polymerase-binding transcription factor DksA	120
651497348	430	36.88	7	425	1	412	9.0e-96	343	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
651497349	167	49.06	1	159	1	159	4.0e-52	197	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
651497350	452	63	1	444	2	446	3.0e-129	455	COG3069	C4-dicarboxylate transporter	451
651497352	1305	38.97	43	965	9	844	0.0e+00	851	COG1643	HrpA-like RNA helicase	845
651497353	127	52.03	5	127	5	122	4.0e-24	103	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
651497354	150	61.9	4	149	1	147	2.0e-30	124	COG2707	Uncharacterized membrane protein, DUF441 family	151
651497355	635	37.88	9	398	8	396	4.0e-71	262	COG0475	Kef-type K+ transport system, membrane component KefB	397
651497356	711	47.89	1	379	2	376	0.0e+00	486	COG0116	23S rRNA G2445 N2-methylase RlmL	381
651497357	343	48.94	16	343	4	318	2.0e-114	406	COG4531	ABC-type Zn2+ transport system, periplasmic component/surface adhesin	318
651497358	253	57.31	1	253	3	257	3.0e-99	354	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
651497359	375	44.33	5	375	2	364	2.0e-112	399	COG2821	Membrane-bound lytic murein transglycosylase	373
651497362	168	61.31	1	168	1	168	2.0e-49	188	COG5413	Uncharacterized integral membrane protein	168
651497363	451	42.98	1	451	7	458	0.0e+00	528	COG0773	UDP-N-acetylmuramate-alanine ligase	459
651497364	396	37.66	1	396	2	396	3.0e-123	435	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
651497365	202	57.65	3	198	2	194	2.0e-76	278	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
651497366	185	41.53	1	182	10	191	1.0e-27	116	COG0558	Phosphatidylglycerophosphate synthase	192
651497370	474	54.18	1	440	1	436	0.0e+00	573	COG0621	tRNA A37 methylthiotransferase MiaB	437
651497371	274	33.81	14	274	1	270	1.0e-37	150	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
651497372	207	26.99	48	199	6	158	3.0e-04	38.4	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
651497373	439	53.42	1	438	1	433	0.0e+00	538	COG1570	Exonuclease VII, large subunit	440
651497374	403	39.14	9	403	10	383	6.0e-116	411	COG2850	Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain	383
651497375	108	57.58	1	99	1	99	2.0e-32	130	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
651497376	138	45.65	1	138	2	139	2.0e-26	111	COG2510	Uncharacterized membrane protein	140
651497377	194	62.3	3	193	1	190	5.0e-76	277	COG0193	Peptidyl-tRNA hydrolase	190
651497378	363	65.05	1	363	1	372	0.0e+00	538	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
651497379	286	54.55	1	286	1	286	3.0e-107	381	COG1946	Acyl-CoA thioesterase	289
651497380	153	55.26	3	151	2	153	3.0e-49	187	COG0328	Ribonuclease HI	154
651497381	253	35.66	4	245	12	242	1.0e-47	183	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
651497384	506	50.62	1	481	1	444	0.0e+00	579	COG1160	Predicted GTPases	444
651497386	179	54.55	1	176	3	175	3.0e-63	234	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
651497387	461	36.18	30	461	3	454	3.0e-91	329	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
651497388	178	62.57	1	178	5	183	4.0e-51	194	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
651497389	215	36.27	14	215	2	187	6.0e-44	170	COG3117	Lipopolysaccharide export system protein LptC	188
651497390	172	44.19	1	172	2	171	8.0e-43	166	COG1934	Lipopolysaccharide export system protein LptA	173
651497391	241	73.97	1	241	2	243	3.0e-114	404	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
651497392	172	31.79	2	150	1	147	7.0e-24	103	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
651497393	282	52.43	1	282	1	286	6.0e-110	390	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
651497394	226	41.1	1	219	24	241	4.0e-52	197	COG1876	LD-carboxypeptidase LdcB, LAS superfamily	241
651497395	377	34.51	1	375	11	407	1.0e-83	303	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
651497396	651	16.76	16	651	39	768	2.0e-23	104	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
651497399	114	38.79	1	114	2	116	1.0e-26	111	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
651497400	172	24.62	2	172	1	199	6.0e-14	70.4	COG3637	Opacity protein and related surface antigens	199
651497401	170	49.04	14	170	1	156	8.0e-47	179	COG3091	Predicted Zn-dependent metalloprotease, SprT family	156
651497402	384	70.54	1	383	2	388	0.0e+00	695	COG0192	S-adenosylmethionine synthetase	388
651497403	196	43.68	6	192	1	189	1.0e-59	222	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
651497405	188	20.54	2	188	29	252	9.0e-14	70.1	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
651497406	558	48.39	1	558	1	556	0.0e+00	614	COG0497	DNA repair ATPase RecN	557
651497407	296	44.21	9	292	1	279	1.0e-77	283	COG0061	NAD kinase	281
651497408	195	39.47	6	195	3	191	4.0e-36	144	COG0576	Molecular chaperone GrpE (heat shock protein)	193
651497409	708	43.98	4	708	3	699	0.0e+00	898	COG1328	Anaerobic ribonucleoside-triphosphate reductase	700
651497410	193	24.49	1	190	7	202	1.0e-43	169	COG1573	Uracil-DNA glycosylase	202
651497411	478	30.24	33	478	8	457	2.0e-58	220	COG0471	Di- and tricarboxylate transporter	461
651497412	436	44.92	1	436	1	443	1.0e-88	320	COG2233	Xanthine/uracil permease	451
651497413	285	42.51	1	285	19	304	2.0e-73	269	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
651497414	327	53.33	15	327	2	304	5.0e-94	338	COG0492	Thioredoxin reductase	305
651497415	586	50.27	23	583	1	557	0.0e+00	637	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
651497416	576	54.5	1	575	1	572	0.0e+00	649	COG4987	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components	573
651497418	155	31.93	1	154	2	167	6.0e-35	140	COG0602	Organic radical activating enzyme	212
651497419	262	34.35	1	262	1	255	1.0e-65	242	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
651497420	183	49.71	15	183	1	157	4.0e-54	203	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
651497421	482	59.44	24	482	1	464	0.0e+00	710	COG0215	Cysteinyl-tRNA synthetase	464
651497424	151	31.91	4	143	5	142	5.0e-19	87.4	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
651497425	95	68.42	1	95	1	95	2.0e-08	50.5	COG3767	Uncharacterized low-complexity protein	95
651497426	306	61.44	1	306	2	282	6.0e-110	390	COG3220	Uncharacterized conserved protein, UPF0276 family	282
651497427	237	50	4	235	1	232	2.0e-78	285	COG3219	Uncharacterized protein	237
651497430	195	25.57	20	195	18	179	4.0e-24	104	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
651497432	186	53.98	3	178	2	177	3.0e-62	231	COG3054	Predicted transcriptional regulator	184
651497433	123	64.29	17	123	1	112	5.0e-39	153	COG2824	Uncharacterized Zn-ribbon-containing protein	112
651497434	385	41.99	103	382	2	279	3.0e-93	335	COG0077	Prephenate dehydratase	279
651497435	546	33.82	2	532	1	501	4.0e-93	335	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
651497436	305	70.53	1	302	1	300	0.0e+00	503	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
651497437	435	46.89	8	361	5	335	2.0e-95	343	COG0206	Cell division GTPase FtsZ	338
651497438	424	45.71	6	424	4	414	8.0e-125	440	COG0849	Cell division ATPase FtsA	418
651497439	261	30.23	6	260	7	258	2.0e-40	159	COG1589	Cell division septal protein FtsQ	269
651497440	316	48.42	14	315	1	316	4.0e-93	334	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
651497441	475	54.18	12	475	1	459	0.0e+00	597	COG0773	UDP-N-acetylmuramate-alanine ligase	459
651497442	350	48.46	3	350	1	356	1.0e-105	376	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
651497443	394	43.63	23	385	13	376	3.0e-84	305	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
651497444	437	43.68	1	435	1	444	0.0e+00	472	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
651497445	360	47.35	27	360	6	316	1.0e-61	230	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
651497446	456	43.6	2	454	1	451	2.0e-130	459	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
651497447	489	45.14	2	489	1	475	0.0e+00	488	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
651497448	606	34.33	28	585	1	599	1.0e-116	414	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
651497449	106	46.67	2	106	1	105	1.0e-27	115	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
651497450	322	56.37	12	320	7	311	1.0e-118	419	COG0275	16S rRNA C1402 N4-methylase RsmH	314
651497451	152	43.42	1	152	1	146	4.0e-44	170	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
651497452	524	36.56	1	517	3	562	2.0e-122	433	COG1966	Carbon starvation protein CstA	575
651497454	685	24.27	245	650	20	457	2.0e-23	104	COG0464	AAA+-type ATPase, SpoVK/Ycf46/Vps4 family	494
651497456	250	23.69	13	246	16	247	2.0e-16	79.3	COG0631	Serine/threonine protein phosphatase PrpC	262
651497457	281	23.81	4	269	1	241	2.0e-26	112	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
651497460	236	42.04	1	234	7	250	1.0e-57	216	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
651497461	296	22.58	1	134	2	150	9.0e-11	61.2	COG4502	5'(3')-deoxyribonucleotidase	180
651497462	328	18.03	23	324	11	294	3.0e-09	56.2	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
651497463	227	52.7	2	221	6	227	6.0e-68	250	COG4160	ABC-type arginine/histidine transport system, permease component	228
651497464	223	49.34	1	220	2	228	3.0e-68	251	COG4215	ABC-type arginine transport system, permease component	230
651497465	239	36.69	4	237	18	263	1.0e-34	139	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
651497466	245	71.6	1	243	1	242	2.0e-118	418	COG4161	ABC-type arginine transport system, ATPase component	242
651497467	208	58.66	16	193	1	176	3.0e-69	254	COG0279	Phosphoheptose isomerase	176
651497470	369	47.73	1	369	2	396	2.0e-130	458	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
651497486	615	20.45	421	597	27	195	1.0e-08	55.8	COG3179	Predicted chitinase	206
651497489	115	18.25	4	112	2	125	1.0e-04	38.4	COG3755	Uncharacterized conserved protein YecT, DUF1311 family	127
651497493	568	27.87	323	566	7	204	2.0e-28	120	COG3179	Predicted chitinase	206
651497498	865	38.52	13	864	2	783	0.0e+00	688	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
651497508	171	38.24	1	170	1	158	6.0e-41	160	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
651497509	1228	27.12	22	1202	8	1188	0.0e+00	666	COG3523	Type VI protein secretion system component VasK	1188
651497512	281	33.2	42	278	19	259	4.0e-47	182	COG3455	Type VI protein secretion system component VasF	262
651497513	448	39.82	1	445	1	446	4.0e-108	385	COG3522	Predicted component of the type VI protein secretion system	446
651497516	332	29.22	14	319	21	323	2.0e-50	193	COG3520	Predicted component of the type VI protein secretion system	335
651497517	583	33.55	1	583	3	621	4.0e-125	442	COG3519	Type VI protein secretion system component VasA	621
651497518	138	28.1	27	137	33	153	3.0e-12	64.6	COG3518	Predicted component of the type VI protein secretion system	157
651497519	494	54.08	3	490	6	491	0.0e+00	700	COG3517	Predicted component of the type VI protein secretion system	495
651497520	165	46.99	2	165	5	168	5.0e-41	160	COG3516	Predicted component of the type VI protein secretion system	169
651497521	89	43.04	6	83	14	92	2.0e-12	64.2	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
651497522	684	39.23	1	544	6	550	0.0e+00	522	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
651497528	462	40.72	122	461	1	359	7.0e-97	348	COG1858	Cytochrome c peroxidase	364
651497529	295	28.15	1	295	2	288	3.0e-42	165	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
651497530	417	32.31	86	371	1	291	2.0e-52	199	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
651497531	280	31.42	45	261	2	218	6.0e-35	141	COG2091	Phosphopantetheinyl transferase	223
651497532	424	34.32	1	424	1	410	1.0e-100	360	COG0498	Threonine synthase	411
651497533	314	42.04	1	314	3	298	1.0e-100	359	COG0083	Homoserine kinase	299
651497534	815	42.3	1	460	3	445	4.0e-126	445	COG0527	Aspartokinase	447
651497536	234	54.55	1	231	1	228	2.0e-80	291	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
651497537	426	64.22	1	422	1	421	0.0e+00	639	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
651497538	94	49.37	10	88	1	79	1.0e-23	101	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
651497539	111	43.27	4	107	1	99	5.0e-21	92.6	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
651497540	215	45.81	5	207	1	202	7.0e-57	213	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
651497542	261	47.89	1	261	7	266	5.0e-70	257	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
651497543	264	61.92	1	259	4	263	3.0e-109	387	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
651497544	513	36.02	10	509	18	517	3.0e-115	409	COG0815	Apolipoprotein N-acyltransferase	518
651497545	298	68.64	1	286	1	285	3.0e-118	418	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
651497546	341	39.94	4	340	1	305	5.0e-66	244	COG2017	Galactose mutarotase or related enzyme	308
651497549	348	60.23	11	348	1	338	2.0e-118	418	COG1085	Galactose-1-phosphate uridylyltransferase	338
651497550	366	41.03	33	360	1	329	3.0e-86	312	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
651497551	331	32.04	1	331	8	317	1.0e-43	170	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
651497552	508	48.1	8	505	1	498	0.0e+00	649	COG1129	ABC-type sugar transport system, ATPase component	500
651497553	336	82.74	1	336	1	336	0.0e+00	497	COG4211	ABC-type glucose/galactose transport system, permease component	336
651497555	64	76.56	1	64	1	64	2.0e-21	93.9	COG2975	Fe-S-cluster formation regulator IscX/YfhJ	64
651497556	113	45.28	1	104	1	102	2.0e-17	80.9	COG0633	Ferredoxin	102
651497557	618	47.41	18	602	4	579	0.0e+00	547	COG0443	Molecular chaperone DnaK (HSP70)	579
651497559	173	38.01	4	173	3	173	4.0e-26	111	COG1076	DnaJ-domain-containing proteins 1	174
651497560	122	60.91	14	122	1	110	3.0e-40	156	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
651497561	127	52.41	1	126	5	146	7.0e-36	142	COG0822	NifU homolog involved in Fe-S cluster formation	150
651497562	404	60.87	3	388	1	386	0.0e+00	565	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
651497563	151	46.38	1	137	1	138	1.0e-40	158	COG1959	DNA-binding transcriptional regulator, IscR family	150
651497564	239	51.43	1	239	1	241	1.0e-78	285	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
651497569	427	47.67	10	425	1	425	1.0e-105	377	COG0823	Periplasmic component of the Tol biopolymer transport system	425
651497570	415	44.23	1	412	3	387	7.0e-33	135	COG3064	Membrane protein involved in colicin uptake	387
651497571	157	36.5	21	157	6	135	9.0e-25	106	COG0848	Biopolymer transport protein ExbD	137
651497572	228	40.74	10	225	1	216	2.0e-51	195	COG0811	Biopolymer transport protein ExbB/TolQ	216
651497573	142	44.19	14	142	6	133	2.0e-34	138	COG0824	Acyl-CoA thioesterase FadM	137
651497574	96	34.78	1	92	3	94	7.0e-15	72.2	COG3790	Predicted membrane protein, encoded in cydAB operon	97
651497575	379	47.62	1	374	1	346	2.0e-84	306	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
651497578	335	71.08	4	335	1	332	0.0e+00	552	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
651497579	203	51.71	1	203	1	201	3.0e-61	228	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
651497580	190	61.78	5	160	1	157	3.0e-58	218	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
651497582	246	61.98	1	240	1	241	2.0e-99	355	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
651497583	152	21.88	12	137	14	139	7.0e-11	60	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
651497584	422	23.67	1	422	1	416	4.0e-40	159	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
651497587	590	61.59	2	587	1	585	0.0e+00	939	COG0173	Aspartyl-tRNA synthetase	585
651497589	867	27.01	1	676	1	638	1.0e-37	152	COG4984	Uncharacterized membrane protein	644
651497590	442	49.55	1	439	1	438	0.0e+00	480	COG2271	Sugar phosphate permease	448
651497591	135	27.66	1	125	1	138	3.0e-15	74.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
651497592	229	32.07	13	222	3	238	9.0e-24	103	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
651497593	450	61.78	3	450	1	444	0.0e+00	549	COG2056	Predicted histidine transporter YuiF, NhaC family	444
651497594	193	26.74	1	185	1	174	4.0e-14	71.2	COG3923	Primosomal replication protein N''	175
651497598	573	16.67	16	573	159	715	9.0e-04	39	COG5295	Autotransporter adhesin	715
651497600	399	24.16	118	366	34	296	3.0e-16	80.3	COG4974	Site-specific recombinase XerD	300
651497602	937	54.56	1	491	1	487	0.0e+00	544	COG1530	Ribonuclease G or E	487
651497603	326	41.2	13	309	1	289	1.0e-75	276	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
651497604	94	68.83	1	76	1	77	7.0e-26	108	COG1923	sRNA-binding regulator protein Hfq	77
651497605	451	48.44	34	448	4	411	2.0e-125	442	COG2262	50S ribosomal subunit-associated GTPase HflX	411
651497607	302	47.89	20	301	39	320	1.0e-83	303	COG4607	ABC-type enterochelin transport system, periplasmic component	320
651497608	253	64.54	3	253	2	252	4.0e-104	371	COG4604	ABC-type enterochelin transport system, ATPase component	252
651497609	319	52.23	4	317	3	316	9.0e-83	300	COG4605	ABC-type enterochelin transport system, permease component	316
651497610	330	60.44	14	329	4	319	5.0e-99	354	COG4606	ABC-type enterochelin transport system, permease component	321
651497611	491	38.14	271	459	65	258	1.0e-36	147	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
651497612	264	38.98	12	246	2	254	4.0e-76	277	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
651497613	261	44.57	1	258	10	267	2.0e-46	179	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
651497614	315	68.57	2	315	1	315	0.0e+00	506	COG0825	Acetyl-CoA carboxylase alpha subunit	317
651497615	288	48.43	2	288	1	281	2.0e-92	332	COG2240	Pyridoxal/pyridoxine/pyridoxamine kinase	281
651497616	430	31.07	17	287	23	289	3.0e-44	173	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
651497617	223	69.27	1	218	9	226	7.0e-104	369	COG3066	DNA mismatch repair protein MutH	229
651497618	197	38.69	21	177	1	168	2.0e-41	162	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
651497619	455	45.92	1	455	2	440	2.0e-109	390	COG2067	Long-chain fatty acid transport protein	440
651497620	95	56.84	1	95	4	98	2.0e-27	113	COG3691	Uncharacterized conserved protein YfcZ, UPF0381/DUF406 family	98
651497621	345	65.8	3	345	1	345	0.0e+00	532	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
651497622	212	53.5	2	201	1	200	3.0e-77	281	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
651497624	184	51.67	1	180	1	180	2.0e-52	198	COG2917	Intracellular septation protein A	180
651497625	154	48.23	7	147	4	141	2.0e-45	174	COG1607	Acyl-CoA hydrolase	157
651497626	99	61.22	2	99	1	92	3.0e-26	109	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
651497628	102	49.51	1	99	1	103	7.0e-29	118	COG2973	Trp operon repressor	103
651497631	480	45.19	8	474	3	472	0.0e+00	524	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
651497636	330	20.12	21	328	58	356	5.0e-37	148	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
651497637	580	47.61	1	580	1	600	0.0e+00	709	COG3083	Membrane-anchored periplasmic protein YejM, alkaline phosphatase superfamily	600
651497638	72	58.57	1	70	1	70	4.0e-19	86.2	COG3082	Uncharacterized conserved protein YejL, UPF0352 family	74
651497639	338	60.36	1	338	1	335	0.0e+00	502	COG3081	Nucleoid-associated protein YejK (function unknown)	335
651497640	137	38.46	1	137	4	145	1.0e-30	125	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
651497641	235	43.35	3	233	2	226	3.0e-59	221	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
651497642	467	28.43	158	467	34	333	3.0e-38	153	COG0642	Signal transduction histidine kinase	336
651497643	722	40.83	5	718	2	709	0.0e+00	678	COG2217	Cation transport ATPase	713
651497644	69	52.17	1	69	1	69	5.0e-12	62.7	COG2608	Copper chaperone CopZ	71
651497645	128	35.48	1	123	1	124	5.0e-20	90.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
651497646	105	86.67	1	105	1	105	3.0e-51	193	COG3060	Transcriptional regulator of met regulon	105
651497647	295	58.64	1	295	5	291	4.0e-118	417	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
651497648	63	63.49	1	63	1	63	7.0e-17	78.8	COG1551	sRNA-binding carbon storage regulator CsrA	73
651497649	874	57.64	1	874	5	879	0.0e+00	1206	COG0013	Alanyl-tRNA synthetase	879
651497650	141	27.81	1	140	4	154	2.0e-11	61.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
651497651	430	31.13	24	425	6	384	3.0e-71	262	COG0006	Xaa-Pro aminopeptidase	384
651497652	182	51.09	1	182	4	186	5.0e-59	220	COG3079	Uncharacterized conserved protein YgfB, UPF0149 family	186
651497653	548	49.08	1	530	1	519	0.0e+00	490	COG0459	Chaperonin GroEL (HSP60 family)	524
651497654	96	59.38	1	96	1	95	9.0e-28	114	COG0234	Co-chaperonin GroES (HSP10)	96
651497655	472	73.52	1	472	1	471	0.0e+00	816	COG1027	Aspartate ammonia-lyase	471
651497659	200	59.26	12	197	1	189	5.0e-65	240	COG0164	Ribonuclease HII	199
651497660	389	54.69	6	386	2	381	0.0e+00	470	COG0763	Lipid A disaccharide synthetase	381
651497661	262	62.69	3	262	1	260	1.0e-109	389	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
651497662	149	58.74	9	149	3	144	2.0e-47	181	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
651497663	341	54.28	2	340	1	338	1.0e-112	400	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
651497664	202	34.21	1	190	1	170	4.0e-17	81.5	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
651497665	795	40.48	1	795	3	766	0.0e+00	714	COG4775	Outer membrane protein assembly factor BamA	766
651497667	288	37.85	1	287	1	265	3.0e-36	145	COG0575	CDP-diglyceride synthetase	265
651497668	239	57.33	7	238	14	245	2.0e-94	338	COG0020	Undecaprenyl pyrophosphate synthase	245
651497669	399	58.19	3	398	1	383	0.0e+00	556	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
651497670	185	64.86	1	185	3	187	6.0e-65	240	COG0233	Ribosome recycling factor	187
651497671	237	59.07	2	237	1	237	7.0e-92	330	COG0528	Uridylate kinase	238
651497672	519	26.18	3	449	36	489	4.0e-68	252	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
651497673	283	57.09	1	281	1	296	1.0e-92	332	COG0264	Translation elongation factor EF-Ts	296
651497674	251	64.58	12	251	1	239	4.0e-99	354	COG0052	Ribosomal protein S2	252
651497676	418	43.78	1	413	3	415	3.0e-75	275	COG0814	Amino acid permease	415
651497677	259	23.11	42	248	79	301	2.0e-24	106	COG0501	Zn-dependent protease with chaperone function	302
651497678	1034	38.74	2	1010	1	1007	0.0e+00	878	COG0841	Multidrug efflux pump subunit AcrB	1009
651497679	398	29.31	47	316	32	321	4.0e-26	112	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
651497680	192	20	1	192	1	195	2.0e-12	65.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
651497681	287	34.31	20	287	11	262	4.0e-29	122	COG3087	Cell division protein FtsN	264
651497682	729	47.83	1	728	1	730	0.0e+00	856	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
651497683	248	48	28	248	1	225	5.0e-70	257	COG0220	tRNA G46 methylase TrmB	227
651497684	113	70.64	2	110	11	119	8.0e-44	168	COG3171	Uncharacterized conserved protein YggL, DUF469 family	119
651497686	87	47.56	5	86	1	81	1.0e-14	71.5	COG3062	Cytoplasmic chaperone NapD for the signal peptide of periplasmic nitrate reductase NapAB	94
651497687	828	30.69	2	828	1	764	0.0e+00	560	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
651497690	142	38.13	4	139	15	153	9.0e-35	139	COG3043	Nitrate reductase cytochrome c-type subunit	155
651497691	212	57.67	6	193	2	190	2.0e-65	242	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
651497692	629	29.74	251	620	33	385	1.0e-86	314	COG0754	Glutathionylspermidine synthase	387
651497693	357	31.56	117	355	15	254	1.0e-43	170	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
651497694	455	25.59	20	442	56	437	7.0e-55	208	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
651497695	289	31.52	14	285	2	239	5.0e-61	228	COG0688	Phosphatidylserine decarboxylase	239
651497696	210	51.71	6	210	1	205	3.0e-62	231	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
651497698	369	56.52	3	369	4	369	0.0e+00	490	COG0263	Glutamate 5-kinase	369
651497699	177	46.75	18	176	1	167	2.0e-41	161	COG0262	Dihydrofolate reductase	167
651497700	441	50	1	438	1	442	0.0e+00	484	COG2271	Sugar phosphate permease	448
651497701	321	57.65	1	320	1	340	7.0e-116	410	COG0205	6-phosphofructokinase	347
651497703	258	59.14	1	257	1	253	4.0e-90	324	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
651497704	367	39.84	1	367	1	350	5.0e-97	348	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
651497705	515	48.67	3	414	1	409	9.0e-123	434	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
651497706	358	57.73	1	358	1	345	0.0e+00	468	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
651497707	469	59.36	1	466	1	422	0.0e+00	637	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
651497708	200	57.71	1	200	1	191	2.0e-80	291	COG0066	3-isopropylmalate dehydratase small subunit	191
651497709	1230	58.99	327	1199	1	842	0.0e+00	1173	COG1410	Methionine synthase I, cobalamin-binding domain	842
651497714	473	36.84	98	468	4	375	3.0e-74	272	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
651497716	115	52.87	1	87	1	86	9.0e-18	82.2	COG1314	Preprotein translocase subunit SecG	86
651497717	647	32.06	1	626	1	569	0.0e+00	521	COG0550	DNA topoisomerase IA	570
651497718	200	56.28	1	199	1	198	1.0e-85	309	COG0353	Recombinational DNA repair protein RecR	198
651497719	109	62.62	1	106	1	105	2.0e-27	113	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
651497720	363	29.35	114	363	12	284	2.0e-24	107	COG1408	Predicted phosphohydrolase, MPP superfamily	284
651497721	456	52.3	170	452	1	262	1.0e-89	323	COG1760	L-serine deaminase	262
651497722	412	37.47	7	412	5	412	3.0e-74	272	COG0814	Amino acid permease	415
651497725	359	22.65	49	353	1	296	2.0e-32	133	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
651497726	90	82.22	1	90	1	90	8.0e-41	158	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
651497727	372	48.51	1	368	1	342	7.0e-120	423	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
651497728	70	61.64	1	70	1	73	9.0e-22	95.3	COG0254	Ribosomal protein L31	75
651497729	701	17.91	66	701	103	768	5.0e-32	133	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
651497730	755	42.56	35	755	32	699	0.0e+00	600	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
651497731	235	38.4	1	231	10	233	4.0e-36	145	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
651497732	438	21.13	46	433	37	389	1.0e-16	81.4	COG2814	Predicted arabinose efflux permease, MFS family	394
651497733	275	45.49	1	255	1	249	4.0e-80	291	COG0121	Predicted glutamine amidotransferase	252
651497734	456	39.26	1	456	1	454	1.0e-126	447	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
651497735	139	33.09	2	136	1	136	2.0e-29	121	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
651497736	323	44.62	2	322	1	318	4.0e-101	361	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
651497737	361	18.26	2	361	3	354	4.0e-33	135	COG3203	Outer membrane protein (porin)	354
651497738	333	68.77	17	333	7	322	0.0e+00	478	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
651497739	603	51.82	6	575	3	562	0.0e+00	614	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
651497740	256	45.93	6	250	2	234	4.0e-85	307	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
651497741	136	59.23	6	135	2	128	3.0e-42	164	COG3029	Fumarate reductase subunit C	129
651497742	114	61.02	1	114	1	118	3.0e-37	146	COG3080	Fumarate reductase subunit D	118
651497744	149	53.69	1	149	1	147	4.0e-43	167	COG0359	Ribosomal protein L9	148
651497745	76	73.53	1	68	8	75	3.0e-21	93	COG0238	Ribosomal protein S18	75
651497746	108	64.36	8	108	3	103	3.0e-37	146	COG2965	Primosomal replication protein N	103
651497747	125	52.73	2	110	1	110	9.0e-35	138	COG0360	Ribosomal protein S6	112
651497748	72	69.44	1	72	1	72	7.0e-26	108	COG0361	Translation initiation factor IF-1	75
651497749	225	26.07	2	206	1	206	6.0e-25	107	COG3306	Glycosyltransferase involved in LPS biosynthesis, GR25 family	255
651497750	343	21.78	31	339	1	320	1.0e-31	130	COG0859	ADP-heptose:LPS heptosyltransferase	334
651497751	287	51.32	11	274	4	259	3.0e-95	341	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
651497752	381	17.14	4	380	1	380	2.0e-15	77.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
651497753	296	30.71	1	279	3	282	1.0e-50	193	COG1442	Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase	325
651497754	282	36.47	7	268	4	255	3.0e-47	182	COG3306	Glycosyltransferase involved in LPS biosynthesis, GR25 family	255
651497755	275	16.98	109	263	16	155	5.0e-10	58.5	COG0639	Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family	155
651497757	444	39.31	1	433	3	405	5.0e-114	404	COG1252	NADH dehydrogenase, FAD-containing subunit	405
651497758	285	60.28	4	284	1	282	1.0e-111	396	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
651497762	580	37	23	578	10	553	2.0e-111	396	COG0659	Sulfate permease or related transporter, MFS superfamily	554
651497763	238	59.24	1	237	8	230	5.0e-81	294	COG0689	Ribonuclease PH	230
651497764	213	36.32	3	211	1	201	1.0e-50	192	COG0461	Orotate phosphoribosyltransferase	201
651497765	288	27.36	71	282	1	174	5.0e-31	128	COG1076	DnaJ-domain-containing proteins 1	174
651497766	307	38.34	1	307	11	314	4.0e-76	278	COG0042	tRNA-dihydrouridine synthase	323
651497767	283	40.56	33	279	1	246	9.0e-62	230	COG3338	Carbonic anhydrase	250
651497768	285	57.3	12	285	1	272	9.0e-110	390	COG0253	Diaminopimelate epimerase	272
651497769	208	44.71	1	206	1	201	9.0e-57	213	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
651497770	827	60.3	10	812	1	809	0.0e+00	1094	COG2937	Glycerol-3-phosphate O-acyltransferase	810
651497771	461	31.53	14	460	8	457	6.0e-60	225	COG0471	Di- and tricarboxylate transporter	461
651497772	166	40.24	3	166	11	179	8.0e-45	173	COG0684	Regulator of RNase E activity RraA	210
651497773	303	44.88	1	303	3	300	5.0e-77	281	COG1575	1,4-dihydroxy-2-naphthoate octaprenyltransferase	303
651497774	245	53.75	2	161	1	152	2.0e-50	192	COG1720	tRNA (Thr-GGU) A37 N-methylase	156
651497775	348	34.29	4	348	1	342	2.0e-33	136	COG0628	Predicted PurR-regulated permease PerM	355
651497776	116	40.52	1	116	1	115	3.0e-27	113	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
651497777	84	67.8	15	72	5	63	3.0e-14	70	COG3036	Stalled ribosome alternative rescue factor ArfA	66
651497779	333	30.79	1	332	4	342	1.0e-68	253	COG3317	Uncharacterized lipoprotein	342
651497780	298	51.69	4	298	1	296	8.0e-93	333	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
651497781	155	55.48	1	155	1	155	6.0e-57	213	COG1225	Peroxiredoxin	157
651497783	158	39.53	2	127	11	137	2.0e-23	101	COG0848	Biopolymer transport protein ExbD	137
651497784	266	32.95	7	265	1	241	1.0e-26	113	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
651497785	99	75.76	1	99	1	98	1.0e-35	141	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
651497786	326	43.69	1	322	2	323	9.0e-96	343	COG0042	tRNA-dihydrouridine synthase	323
651497787	295	53.51	1	293	2	300	3.0e-101	361	COG2264	Ribosomal protein L11 methylase PrmA	300
651497788	291	20.82	18	284	31	285	9.0e-09	54.5	COG5006	Threonine/homoserine efflux transporter RhtA	292
651497789	474	69.28	3	474	1	471	0.0e+00	593	COG4145	Na+/panthothenate symporter	473
651497790	84	55	3	82	1	80	7.0e-29	118	COG3924	Uncharacterized membrane protein YhdT	80
651497793	448	66.74	1	446	1	447	0.0e+00	643	COG0439	Biotin carboxylase	449
651497794	151	54.11	6	151	1	139	3.0e-26	111	COG0511	Biotin carboxyl carrier protein	140
651497796	150	58.62	6	150	2	146	1.0e-57	215	COG0757	3-dehydroquinate dehydratase	146
651497797	329	64.31	4	327	2	321	0.0e+00	518	COG1441	O-succinylbenzoate synthase	321
651497798	297	77.3	18	297	1	282	0.0e+00	527	COG0447	1,4-Dihydroxy-2-naphthoyl-CoA synthase	282
651497800	389	43.78	17	385	3	349	4.0e-105	375	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
651497801	552	31.16	44	545	2	464	9.0e-89	321	COG1109	Phosphomannomutase	464
651497802	302	63.61	9	302	1	294	5.0e-116	410	COG2103	N-acetylmuramic acid 6-phosphate (MurNAc-6-P) etherase	298
651497803	372	52.83	3	372	6	371	2.0e-128	452	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
651497804	232	42.54	4	231	2	217	5.0e-50	191	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
651497805	470	56.8	4	464	1	459	0.0e+00	644	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
651497807	533	36.09	1	531	2	520	1.0e-113	403	COG1620	L-lactate permease	522
651497808	279	35.57	1	279	13	305	5.0e-67	247	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
651497809	287	56.21	1	287	1	290	2.0e-90	325	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
651497810	404	36.19	1	399	8	415	2.0e-55	210	COG0814	Amino acid permease	415
651497812	261	46.24	1	261	11	272	2.0e-83	302	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
651497813	371	57.22	18	369	2	352	0.0e+00	460	COG0407	Uroporphyrinogen-III decarboxylase	352
651497814	196	59.79	1	194	2	194	5.0e-78	283	COG3068	Uncharacterized protein YjaG, DUF416 family	194
651497815	90	63.33	1	90	2	91	1.0e-25	107	COG0776	Bacterial nucleoid DNA-binding protein	94
651497816	260	44.27	9	258	2	253	6.0e-57	214	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
651497817	610	57.28	1	610	1	597	0.0e+00	832	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
651497818	234	52.79	5	234	1	232	2.0e-72	265	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
651497819	240	31.38	6	238	2	236	2.0e-35	143	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
651497820	478	30.88	15	478	1	449	9.0e-72	264	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
651497822	119	34.45	2	119	1	104	1.0e-19	88.8	COG2315	Predicted DNA-binding protein with ?double-wing? structural motif, MmcQ/YjbR family	118
651497823	325	22.87	1	320	1	315	2.0e-18	86.8	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
651497824	265	26.61	21	265	9	255	9.0e-30	124	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
651497825	230	35.93	1	216	3	232	2.0e-40	158	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
651497826	365	30.89	5	364	16	396	1.0e-60	227	COG3213	Uncharacterized protein involved in response to NO	396
651497827	127	33.33	1	121	1	123	6.0e-18	82.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
651497828	231	35.24	32	229	3	212	6.0e-42	164	COG1230	Co/Zn/Cd efflux system component	296
651497829	118	47.41	1	115	2	117	2.0e-32	131	COG1539	Dihydroneopterin aldolase	121
651497830	199	48	1	193	1	200	3.0e-56	211	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
651497831	293	37.68	13	291	54	331	1.0e-69	256	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
651497832	103	60.58	1	103	1	104	1.0e-37	147	COG4390	Uncharacterized protein	106
651497833	341	37.54	2	333	7	291	2.0e-89	322	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
651497834	567	44.06	4	563	2	567	0.0e+00	588	COG3850	Signal transduction histidine kinase, nitrate/nitrite-specific	574
651497835	404	22.31	9	396	12	387	4.0e-22	99.5	COG2814	Predicted arabinose efflux permease, MFS family	394
651497838	237	41.24	58	237	41	228	4.0e-53	201	COG3719	Ribonuclease I	249
651497839	386	57.64	1	385	2	395	0.0e+00	496	COG0126	3-phosphoglycerate kinase	395
651497840	359	34.99	17	357	5	284	6.0e-90	324	COG0191	Fructose/tagatose bisphosphate aldolase	286
651497841	414	23.43	8	414	21	423	1.0e-18	87.5	COG3307	O-antigen ligase	424
651497842	342	25.51	1	338	2	334	1.0e-58	220	COG0859	ADP-heptose:LPS heptosyltransferase	334
651497843	221	42.86	10	218	2	204	1.0e-43	169	COG2364	Uncharacterized membrane protein YczE	210
651497845	621	58.31	15	613	2	589	0.0e+00	779	COG0514	Superfamily II DNA helicase RecQ	590
651497846	101	51.43	1	101	1	105	1.0e-32	131	COG1965	Iron-binding protein CyaY, frataxin homolog	106
651497847	41	41.86	1	41	1	43	7.0e-04	35.4	COG5567	Predicted small periplasmic lipoprotein YifL (function unknown0	58
651497848	416	50.25	1	391	1	394	5.0e-128	451	COG0019	Diaminopimelate decarboxylase	394
651497849	455	39.86	12	443	1	414	3.0e-121	428	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
651497851	185	48.66	1	185	1	169	7.0e-35	140	COG3078	Ribosome assembly protein YihI, activator of Der GTPase	169
651497855	116	67.86	3	114	4	115	5.0e-41	159	COG0335	Ribosomal protein L19	115
651497856	246	58.68	1	241	1	240	3.0e-110	391	COG0336	tRNA G37 N-methylase TrmD	240
651497857	175	55.03	8	175	9	172	7.0e-53	200	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
651497858	81	62.96	1	81	1	80	2.0e-27	114	COG0228	Ribosomal protein S16	87
651497861	367	83.92	1	367	28	394	0.0e+00	668	COG0050	Translation elongation factor EF-Tu, a GTPase	394
651497862	212	23.18	7	200	3	233	1.0e-17	82.9	COG1192	Cellulose biosynthesis protein BcsQ	259
