gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
638021406	450	43.82	18	444	1	407	3.0e-113	402	COG0593	Chromosomal replication initiation ATPase DnaA	408
638021407	633	24.57	351	633	21	301	8.0e-06	46.1	COG1413	HEAT repeat	335
638021409	203	34.62	72	199	4	132	3.0e-15	75.3	COG5502	Uncharacterized conserved protein, DUF2267 family	135
638021412	411	22.44	55	405	50	390	3.0e-09	56.8	COG2814	Predicted arabinose efflux permease, MFS family	394
638021414	189	35.07	31	163	8	140	3.0e-13	68.5	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
638021416	259	31.88	22	250	17	240	2.0e-42	166	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
638021418	631	30.1	53	353	34	311	3.0e-42	167	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
638021419	322	33.13	4	317	1	316	4.0e-51	195	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
638021420	570	26.87	24	298	1	279	3.0e-33	137	COG0515	Serine/threonine protein kinase	384
638021425	935	26.53	17	291	1	279	4.0e-31	130	COG0515	Serine/threonine protein kinase	384
638021426	631	33.7	10	631	70	705	1.0e-114	407	COG0557	Exoribonuclease R	706
638021432	320	22.7	6	166	21	174	5.0e-10	58.9	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
638021436	256	23.78	75	254	32	206	1.0e-11	63.8	COG0560	Phosphoserine phosphatase	212
638021437	336	30.24	5	330	3	328	7.0e-33	134	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
638021438	253	35.08	1	248	9	256	2.0e-38	152	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
638021439	259	50.86	2	233	17	248	3.0e-83	301	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
638021442	361	30.35	1	360	1	350	2.0e-36	146	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
638021443	621	30.05	17	619	16	610	2.0e-103	370	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
638021454	347	31.14	8	330	5	335	1.0e-44	173	COG5351	Uncharacterized protein	367
638021457	414	30.03	81	404	33	363	1.0e-45	177	COG4850	Phosphatidate phosphatase APP1	373
638021458	720	52.23	25	712	3	691	0.0e+00	827	COG0855	Polyphosphate kinase	696
638021462	758	32.19	453	741	44	329	2.0e-38	154	COG0642	Signal transduction histidine kinase	336
638021463	298	20.15	25	292	18	236	8.0e-07	47.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
638021464	119	21.93	3	114	11	124	6.0e-10	56.2	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
638021466	450	32.97	20	448	1	432	3.0e-72	266	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
638021470	346	27.53	124	301	5	170	1.0e-11	64.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638021471	477	22.16	5	198	11	201	3.0e-07	50.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638021473	254	22.3	91	238	26	165	4.0e-08	52.4	COG3652	Predicted outer membrane protein	170
638021474	154	26.56	28	154	14	139	5.0e-14	70.8	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
638021475	150	34.15	27	149	19	138	1.0e-19	89.3	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
638021477	1057	23.38	626	1015	10	400	2.0e-33	138	COG1228	Imidazolonepropionase or related amidohydrolase	406
638021478	154	34.57	1	152	3	157	1.0e-20	92.7	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
638021480	292	37.85	12	255	3	249	5.0e-39	154	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638021481	222	24.12	23	221	4	201	8.0e-06	44.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638021483	538	41.01	12	538	1	526	0.0e+00	532	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
638021484	664	50.3	3	660	1	645	0.0e+00	720	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
638021489	400	26.7	9	389	5	382	2.0e-28	120	COG2814	Predicted arabinose efflux permease, MFS family	394
638021490	356	44.14	11	333	6	322	2.0e-83	302	COG3491	Isopenicillin N synthase and related dioxygenases	322
638021491	214	36.73	22	208	14	208	2.0e-24	106	COG0625	Glutathione S-transferase	211
638021493	378	35.26	8	366	12	365	8.0e-25	108	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
638021494	1046	49.03	1	1025	2	1009	0.0e+00	947	COG0841	Multidrug efflux pump subunit AcrB	1009
638021495	122	28.71	2	100	13	108	9.0e-10	55.7	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
638021496	358	27.97	94	325	85	291	1.0e-19	90.9	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
638021497	768	30.04	362	628	93	335	5.0e-33	136	COG0642	Signal transduction histidine kinase	336
638021498	248	26.61	34	243	70	270	1.0e-12	67.2	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
638021499	409	22.26	50	341	37	321	5.0e-16	79.3	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
638021502	501	23.26	139	467	58	395	9.0e-17	81.9	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
638021506	308	25.94	9	237	6	236	3.0e-15	76.2	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
638021507	583	22.19	44	371	31	385	1.0e-14	75.2	COG2814	Predicted arabinose efflux permease, MFS family	394
638021509	408	28.16	22	408	1	419	1.0e-32	134	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
638021510	405	30.55	19	405	2	419	2.0e-36	146	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
638021512	415	31.63	24	415	30	438	1.0e-56	213	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
638021515	560	22.58	139	458	7	366	3.0e-14	74.2	COG3517	Predicted component of the type VI protein secretion system	495
638021518	446	45.29	115	443	120	459	5.0e-90	325	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638021519	924	25.85	48	363	2	285	5.0e-33	137	COG0515	Serine/threonine protein kinase	384
638021523	494	39.34	14	487	2	472	2.0e-103	369	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638021524	454	26.84	246	433	19	192	1.0e-29	124	COG0807	GTP cyclohydrolase II	193
638021526	211	57.62	3	211	1	210	2.0e-78	285	COG0035	Uracil phosphoribosyltransferase	210
638021533	433	28.27	1	408	10	437	2.0e-42	167	COG0038	H+/Cl- antiporter ClcA	443
638021538	541	28.79	16	540	20	515	1.0e-43	171	COG0815	Apolipoprotein N-acyltransferase	518
638021540	507	23.47	1	504	1	539	4.0e-48	186	COG2303	Choline dehydrogenase or related flavoprotein	542
638021549	282	32.41	45	256	1	209	2.0e-22	99	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
638021550	1074	24.46	5	1057	1	984	1.0e-68	255	COG4717	Uncharacterized protein YhaN	984
638021551	417	25.62	4	342	2	344	2.0e-30	127	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
638021555	452	21.64	113	450	1	330	3.0e-20	93.3	COG0642	Signal transduction histidine kinase	336
638021557	295	61.11	6	293	5	292	7.0e-73	267	COG5006	Threonine/homoserine efflux transporter RhtA	292
638021560	261	29.23	1	258	1	282	1.0e-22	100	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638021562	231	34.2	10	231	17	244	2.0e-38	152	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
638021563	219	31.34	10	207	23	209	1.0e-24	106	COG4117	Thiosulfate reductase cytochrome b subunit	221
638021566	573	64.88	5	565	4	558	0.0e+00	726	COG2060	K+-transporting ATPase, A chain	560
638021567	686	69.74	6	686	2	681	0.0e+00	1008	COG2216	High-affinity K+ transport system, ATPase chain B	681
638021568	211	54.21	1	189	1	190	7.0e-64	237	COG2156	K+-transporting ATPase, c chain	190
638021570	615	27.04	144	611	5	453	4.0e-54	206	COG5002	Signal transduction histidine kinase	459
638021574	453	46.37	5	448	2	454	1.0e-120	427	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638021576	530	31.41	184	530	66	408	2.0e-35	143	COG0840	Methyl-accepting chemotaxis protein	408
638021577	551	53.56	2	547	10	553	0.0e+00	703	COG2759	Formyltetrahydrofolate synthetase	554
638021578	642	28.84	272	638	100	447	6.0e-51	195	COG5002	Signal transduction histidine kinase	459
638021579	293	39.11	1	243	5	251	4.0e-14	72.4	COG0730	Uncharacterized membrane protein YfcA	258
638021580	203	34.95	17	117	7	108	8.0e-14	70.7	COG0607	Rhodanese-related sulfurtransferase	110
638021581	234	32.59	1	195	13	235	8.0e-23	100	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
638021582	460	40.55	43	455	123	558	5.0e-105	375	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
638021583	443	20.11	49	402	1	344	1.0e-28	121	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
638021588	643	22.91	67	623	2	571	1.0e-24	108	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
638021590	710	22.36	163	396	101	337	2.0e-14	75	COG4219	Signal transducer regulating beta-lactamase production, contains  metallopeptidase domain	337
638021591	143	30.83	22	141	5	122	2.0e-15	75.3	COG3682	Predicted transcriptional regulator	123
638021592	252	20.48	17	216	68	257	3.0e-06	45.9	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
638021596	967	28.99	461	818	5	353	1.0e-37	152	COG3852	Signal transduction histidine kinase, nitrogen specific	363
638021597	635	32.83	287	616	11	329	4.0e-42	166	COG0642	Signal transduction histidine kinase	336
638021599	171	29.38	11	170	8	148	5.0e-07	47.6	COG0782	Transcription elongation factor, GreA/GreB family	151
638021600	93	46.99	8	88	11	93	6.0e-15	72.3	COG0607	Rhodanese-related sulfurtransferase	110
638021601	318	20.87	54	306	46	292	3.0e-08	53	COG5006	Threonine/homoserine efflux transporter RhtA	292
638021602	314	30.32	58	311	9	282	2.0e-30	126	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638021603	431	25.16	1	410	1	473	4.0e-28	119	COG1233	Phytoene dehydrogenase-related protein	487
638021604	321	30	1	178	9	174	3.0e-22	99.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638021606	280	27.11	9	256	2	272	3.0e-22	99.1	COG0682	Prolipoprotein diacylglyceryltransferase	287
638021611	798	33.21	521	789	37	296	1.0e-22	102	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
638021612	248	34.09	1	246	1	250	1.0e-32	133	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638021613	406	44.1	20	406	69	458	5.0e-106	378	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
638021614	158	42.38	1	150	4	154	6.0e-31	126	COG1522	DNA-binding transcriptional regulator, Lrp family	154
638021615	247	21.61	13	208	5	201	5.0e-14	71.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638021616	331	45.02	1	330	1	323	4.0e-81	295	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
638021617	519	39.96	1	514	11	530	5.0e-121	428	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
638021621	396	29.56	78	340	18	280	1.0e-25	110	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638021623	345	36.78	3	345	1	326	2.0e-57	216	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
638021626	505	44.68	1	501	10	524	2.0e-120	426	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
638021628	553	34.53	188	549	48	406	2.0e-47	184	COG0840	Methyl-accepting chemotaxis protein	408
638021629	122	24.07	14	67	7	60	6.0e-06	42.9	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
638021630	508	36.53	104	373	73	329	2.0e-42	167	COG0642	Signal transduction histidine kinase	336
638021633	220	23.22	12	220	18	227	3.0e-22	98.8	COG5012	Methanogenic corrinoid protein MtbC1	227
638021634	182	26.06	25	182	16	180	1.0e-11	62.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638021636	368	37.94	1	368	1	364	6.0e-75	274	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
638021638	424	30	261	400	4	140	9.0e-10	58.4	COG3918	Uncharacterized membrane protein	153
638021644	369	47.77	100	256	1	156	2.0e-38	153	COG4335	3-methyladenine DNA glycosylase AlkC	167
638021646	380	37.3	1	369	1	362	7.0e-78	284	COG1195	Recombinational DNA repair ATPase RecF	363
638021649	250	45.31	2	246	17	261	8.0e-50	190	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
638021650	272	47.64	20	272	6	258	1.0e-78	286	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
638021651	402	24.05	11	295	4	274	3.0e-15	76.7	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
638021655	431	24.71	1	431	2	406	5.0e-25	109	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
638021656	386	42.6	1	383	4	381	1.0e-93	337	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
638021660	715	27.67	4	413	2	392	3.0e-49	190	COG0475	Kef-type K+ transport system, membrane component KefB	397
638021661	272	23.84	125	270	2	151	1.0e-10	60.7	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
638021664	815	59.03	17	571	5	559	0.0e+00	828	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
638021665	942	22.64	28	380	1	355	5.0e-39	157	COG0515	Serine/threonine protein kinase	384
638021669	390	37.91	1	389	2	350	1.0e-72	267	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
638021670	258	32.71	28	241	12	212	7.0e-27	114	COG5637	Uncharacterized membrane protein	217
638021672	1076	14.73	476	1075	176	767	9.0e-14	73.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
638021673	141	32.31	1	130	1	125	2.0e-20	91.8	COG0848	Biopolymer transport protein ExbD	137
638021674	135	35.66	5	133	9	136	4.0e-22	97.2	COG0848	Biopolymer transport protein ExbD	137
638021675	250	29.72	9	217	2	210	3.0e-25	108	COG0811	Biopolymer transport protein ExbB/TolQ	216
638021676	269	28.78	66	268	54	244	7.0e-07	48.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
638021678	463	35.59	1	454	1	450	2.0e-95	343	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
638021679	120	32.63	10	104	3	96	8.0e-14	69.1	COG0858	Ribosome-binding factor A	118
638021680	384	31.49	12	384	6	432	4.0e-67	249	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
638021682	175	33.14	6	173	4	175	4.0e-32	131	COG1913	Predicted Zn-dependent protease	181
638021686	735	26.36	289	715	1	386	4.0e-69	256	COG0247	Fe-S oxidoreductase	388
638021689	774	29.45	21	288	10	265	4.0e-22	100	COG4233	Thiol-disulfide interchange protein, contains DsbC and DsbD domains	273
638021689	774	31.53	325	752	138	568	6.0e-69	255	COG4232	Thiol:disulfide interchange protein	569
638021690	193	26.8	24	171	5	148	3.0e-13	68.3	COG1225	Peroxiredoxin	157
638021695	305	39.86	16	286	58	329	4.0e-46	178	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
638021696	313	30.42	6	313	12	342	7.0e-40	157	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
638021698	339	34.43	183	304	9	128	4.0e-25	109	COG3871	General stress protein 26 (function unknown)	145
638021700	397	23.66	1	397	1	400	4.0e-38	152	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
638021703	336	43.63	1	311	1	310	1.0e-90	326	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
638021704	714	30.34	390	710	25	336	3.0e-40	160	COG0642	Signal transduction histidine kinase	336
638021705	439	26.41	48	343	14	332	4.0e-20	93	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
638021709	511	22.02	88	416	37	324	3.0e-16	80.5	COG0714	MoxR-like ATPase	329
638021711	209	39.34	9	209	1	211	4.0e-31	128	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
638021713	358	29.48	6	357	3	358	4.0e-51	195	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
638021716	399	46.51	7	377	8	378	5.0e-106	378	COG3146	Predicted N-acyltransferase	387
638021717	264	23.6	2	237	46	273	4.0e-20	92.3	COG1398	Fatty-acid desaturase	289
638021718	443	41.43	10	442	9	446	9.0e-123	433	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
638021724	204	31.55	17	203	22	208	7.0e-22	97.3	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
638021725	386	29.48	48	375	20	348	4.0e-32	132	COG0628	Predicted PurR-regulated permease PerM	355
638021726	174	56.65	2	174	1	170	4.0e-51	194	COG4675	Microcystin-dependent protein  (function unknown)	170
638021728	169	22.02	1	159	5	165	1.0e-06	46.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
638021731	196	34.78	9	191	1	179	3.0e-22	98.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638021732	409	43.07	255	390	53	189	6.0e-25	108	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
638021734	294	31.53	2	288	12	296	1.0e-41	163	COG0258	5'-3' exonuclease	310
638021735	698	34.01	439	683	96	334	5.0e-39	156	COG0642	Signal transduction histidine kinase	336
638021736	133	32.54	8	133	9	128	1.0e-17	82.3	COG2346	Truncated hemoglobin YjbI	133
638021737	309	32.3	23	277	28	278	1.0e-31	130	COG1398	Fatty-acid desaturase	289
638021739	562	32.36	254	561	35	331	4.0e-43	169	COG0642	Signal transduction histidine kinase	336
638021740	653	58.06	34	653	13	627	0.0e+00	808	COG3158	K+ transporter	627
638021743	245	34.69	1	243	1	230	2.0e-41	162	COG1768	Predicted phosphohydrolase	230
638021746	869	29.81	480	840	98	447	7.0e-49	189	COG5002	Signal transduction histidine kinase	459
638021750	223	25.56	5	218	3	224	3.0e-23	102	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
638021751	329	31.8	44	326	15	318	1.0e-48	187	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
638021752	486	27.34	7	144	22	159	5.0e-10	59.6	COG1716	Forkhead associated (FHA) domain, binds pSer, pThr, pTyr	191
638021757	966	47.13	9	965	1	930	0.0e+00	1098	COG0060	Isoleucyl-tRNA synthetase	933
638021764	254	36.6	99	249	6	158	2.0e-32	132	COG1656	Uncharacterized conserved protein, contains PIN domain	165
638021765	473	23.36	231	449	28	251	2.0e-06	47.7	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
638021767	198	31.25	6	197	11	163	2.0e-29	122	COG0597	Lipoprotein signal peptidase	167
638021768	202	29.26	7	194	12	161	1.0e-26	112	COG0597	Lipoprotein signal peptidase	167
638021769	365	21.41	1	357	1	286	4.0e-30	125	COG0682	Prolipoprotein diacylglyceryltransferase	287
638021773	275	32.82	7	263	7	259	6.0e-44	171	COG0300	Short-chain dehydrogenase	265
638021777	441	40.81	22	440	43	451	2.0e-98	352	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
638021783	109	47.62	1	105	2	106	2.0e-19	87.4	COG2076	Multidrug transporter EmrE and related cation transporters	106
638021784	470	45.83	13	416	4	405	1.0e-112	400	COG1252	NADH dehydrogenase, FAD-containing subunit	405
638021785	129	24.37	8	126	15	125	5.0e-07	46.8	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
638021789	165	43.21	6	164	10	171	4.0e-42	163	COG0684	Regulator of RNase E activity RraA	210
638021790	325	45.65	12	324	6	311	1.0e-76	279	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
638021794	431	57.91	1	429	2	431	0.0e+00	577	COG0001	Glutamate-1-semialdehyde aminotransferase	432
638021795	642	20.62	2	370	6	381	6.0e-39	156	COG0515	Serine/threonine protein kinase	384
638021799	411	46.63	227	397	1	173	7.0e-39	155	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
638021801	303	33.48	48	275	22	243	2.0e-37	149	COG0356	FoF1-type ATP synthase, membrane subunit a	246
638021803	172	34.39	1	157	2	158	3.0e-14	71.4	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
638021804	369	56.95	1	369	1	372	0.0e+00	487	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
638021806	434	33.8	95	425	28	379	8.0e-60	224	COG0372	Citrate synthase	390
638021808	167	32.79	20	141	22	143	2.0e-18	85	COG3837	Uncharacterized conserved protein, cupin superfamily	161
638021811	265	43.51	5	242	4	225	9.0e-52	197	COG2013	Uncharacterized conserved protein, AIM24 family	227
638021813	379	31.69	109	375	5	282	8.0e-36	144	COG1408	Predicted phosphohydrolase, MPP superfamily	284
638021814	364	52.86	12	361	4	351	2.0e-123	435	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
638021820	371	44.87	19	355	80	405	3.0e-87	315	COG1915	Uncharacterized conserved protein, contains Saccharopine dehydrogenase N-terminal (SDHN) domain	415
638021821	604	30.79	56	468	14	392	1.0e-53	205	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638021831	261	23.56	62	247	7	213	2.0e-09	56.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
638021833	708	52.39	1	704	8	690	0.0e+00	817	COG1523	Pullulanase/glycogen debranching enzyme	697
638021837	237	46.88	30	218	17	206	2.0e-48	185	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
638021839	824	21.35	14	798	11	727	8.0e-54	205	COG1033	Predicted exporter protein, RND superfamily	727
638021840	989	21.36	176	973	1	727	1.0e-56	215	COG1033	Predicted exporter protein, RND superfamily	727
638021843	349	27.87	48	339	5	304	4.0e-37	148	COG0492	Thioredoxin reductase	305
638021844	291	34.13	165	290	1	126	4.0e-21	95.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638021849	411	21.17	263	394	1	137	1.0e-05	44.5	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
638021849	411	27.55	73	265	3	192	4.0e-11	62.7	COG0558	Phosphatidylglycerophosphate synthase	192
638021851	444	23.81	13	401	5	347	1.0e-33	138	COG1260	Myo-inositol-1-phosphate synthase	362
638021852	175	36.59	17	139	12	134	1.0e-27	116	COG3871	General stress protein 26 (function unknown)	145
638021855	336	38.53	4	334	3	339	1.0e-86	313	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
638021856	111	24.53	5	110	3	98	2.0e-08	50.6	COG1544	Ribosome-associated translation inhibitor RaiA	110
638021862	467	27.56	27	454	11	384	2.0e-42	167	COG0006	Xaa-Pro aminopeptidase	384
638021866	346	45.15	1	322	1	326	5.0e-79	288	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
638021867	325	28.48	4	322	1	311	9.0e-17	81.3	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
638021868	349	19.38	23	340	4	316	1.0e-16	80.5	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
638021871	90	61.04	11	87	4	80	4.0e-23	99.6	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
638021877	230	27.4	21	225	6	212	3.0e-31	128	COG0602	Organic radical activating enzyme	212
638021878	277	41.57	19	272	18	270	5.0e-68	251	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
638021879	128	23.4	1	125	1	138	5.0e-12	63.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
638021882	396	33.61	40	386	1	335	2.0e-47	183	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
638021895	129	25.21	8	126	15	125	9.0e-08	49.5	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
638021900	636	49.14	1	636	1	597	0.0e+00	762	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
638021901	171	34.39	14	170	3	154	2.0e-27	115	COG1522	DNA-binding transcriptional regulator, Lrp family	154
638021904	453	28.26	3	452	9	438	8.0e-67	248	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
638021913	762	22.74	166	762	40	617	6.0e-47	182	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
638021914	201	26.47	19	154	8	133	4.0e-09	55	COG3415	Transposase	138
638021916	958	22.12	356	958	49	699	3.0e-30	128	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
638021917	191	31.52	24	184	31	194	1.0e-14	73.4	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
638021919	150	26.35	9	149	1	138	2.0e-10	58.9	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
638021923	1274	28.25	21	312	1	277	5.0e-39	157	COG0515	Serine/threonine protein kinase	384
638021925	421	26.65	4	373	1	372	6.0e-19	89	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
638021926	1063	36.06	3	1018	2	1006	0.0e+00	821	COG0841	Multidrug efflux pump subunit AcrB	1009
638021927	654	22.1	49	601	34	495	2.0e-23	104	COG1640	4-alpha-glucanotransferase	520
638021929	434	29.8	30	428	13	391	7.0e-54	205	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
638021930	452	16.39	18	427	11	486	5.0e-38	152	COG3202	ATP/ADP translocase	509
638021931	391	22.58	51	360	2	314	5.0e-20	92.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638021933	1560	29.94	1	633	4	551	9.0e-117	415	COG0550	DNA topoisomerase IA	570
638021935	486	35.9	53	486	1	438	2.0e-71	264	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
638021938	386	34.11	32	361	48	370	6.0e-53	201	COG1219	ATP-dependent protease Clp, ATPase subunit	408
638021939	621	32.43	27	548	36	570	1.0e-111	397	COG0296	1,4-alpha-glucan branching enzyme	628
638021941	526	21.78	63	506	10	389	1.0e-25	111	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
638021946	190	36.55	1	184	1	196	6.0e-32	130	COG0625	Glutathione S-transferase	211
638021950	556	26.53	7	364	1	361	3.0e-37	149	COG0515	Serine/threonine protein kinase	384
638021951	248	19.16	20	230	43	243	3.0e-07	49	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
638021952	310	41.18	3	304	2	293	3.0e-69	255	COG1131	ABC-type multidrug transport system, ATPase component	293
638021954	475	40.38	16	475	8	457	2.0e-108	386	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
638021957	559	44.67	5	540	2	530	0.0e+00	543	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
638021958	302	44.79	5	158	21	183	5.0e-20	92	COG3409	Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases	185
638021959	305	31.33	4	298	13	293	1.0e-43	170	COG0501	Zn-dependent protease with chaperone function	302
638021964	285	25.66	34	285	10	260	9.0e-31	127	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
638021969	755	26.82	409	749	4	336	1.0e-33	138	COG0642	Signal transduction histidine kinase	336
638021972	135	29.93	1	128	2	137	6.0e-20	89.9	COG0394	Protein-tyrosine-phosphatase	139
638021973	139	32.97	1	85	1	91	2.0e-09	55.1	COG3293	Transposase	124
638021975	273	21.81	83	270	61	241	3.0e-10	59.4	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
638021978	247	58.62	7	180	2	175	7.0e-59	220	COG0290	Translation initiation factor IF-3	176
638021979	299	25.69	33	244	26	258	1.0e-14	73.9	COG4676	Uncharacterized conserved protein YfaP, DUF2135 family	268
638021980	222	25	53	218	38	212	2.0e-11	63.1	COG3234	Uncharacterized conserved protein YfaT, DUF1175 family	215
638021982	1572	22.11	191	1564	266	1620	4.0e-72	267	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
638021990	430	25.12	1	428	1	399	4.0e-32	132	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
638021993	252	40.5	1	241	1	240	8.0e-68	250	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
638021994	498	36.62	2	275	15	298	5.0e-62	232	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
638021994	498	54.64	293	486	24	217	1.0e-57	217	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
638021999	323	24.84	1	312	12	322	7.0e-19	88.1	COG1612	Heme A synthase	323
638022003	565	27.21	261	559	14	315	3.0e-30	126	COG0668	Small-conductance mechanosensitive channel	316
638022004	471	40.65	1	457	14	471	2.0e-116	412	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638022006	234	33.15	48	223	43	219	7.0e-09	54.4	COG0671	Membrane-associated phospholipid phosphatase	232
638022007	586	24.68	40	326	25	330	3.0e-31	130	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
638022011	494	27.56	70	360	1	305	2.0e-41	164	COG0515	Serine/threonine protein kinase	384
638022012	357	23.16	58	350	69	419	3.0e-25	109	COG1793	ATP-dependent DNA ligase	444
638022013	162	48.1	6	160	1	157	7.0e-46	176	COG3265	Gluconate kinase	161
638022014	213	34.8	12	211	1	196	2.0e-33	135	COG0288	Carbonic anhydrase	207
638022015	566	48.48	1	329	1	322	1.0e-85	311	COG2376	Dihydroxyacetone kinase	323
638022019	540	43.7	1	534	3	530	0.0e+00	570	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
638022022	479	35.25	1	448	24	466	4.0e-93	335	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638022023	483	34.68	12	455	31	469	7.0e-93	334	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638022026	232	31.06	14	229	1	234	2.0e-22	99.5	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
638022028	257	31.86	114	225	14	126	1.0e-15	76.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638022029	316	21.26	33	265	44	292	4.0e-10	59	COG3239	Fatty acid desaturase	343
638022030	134	27.27	26	80	4	58	2.0e-06	44.8	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
638022032	319	33.33	57	303	7	254	2.0e-42	166	COG1192	Cellulose biosynthesis protein BcsQ	259
638022036	784	28.99	515	720	35	225	8.0e-21	96	COG2114	Adenylate cyclase, class 3	227
638022037	184	55	2	181	7	181	6.0e-53	200	COG3803	Uncharacterized conserved protein, DUF924 family	182
638022038	189	36.94	35	189	2	158	6.0e-26	110	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
638022040	569	28.91	139	550	49	447	1.0e-57	218	COG5002	Signal transduction histidine kinase	459
638022041	882	25.12	39	840	25	853	2.0e-90	327	COG0308	Aminopeptidase N	859
638022043	360	18.59	31	340	5	253	2.0e-08	53.8	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
638022050	611	30.77	171	307	8	147	1.0e-16	82	COG4935	Regulatory P domain of the subtilisin-like proprotein convertases and other proteases	177
638022051	167	40	34	148	1	115	2.0e-13	68.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
638022052	145	51.09	9	144	7	143	3.0e-37	147	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
638022056	600	40.37	66	597	1	534	2.0e-116	413	COG1574	Predicted amidohydrolase YtcJ	535
638022058	257	34.45	1	236	2	209	3.0e-25	109	COG0705	Membrane associated serine protease, rhomboid family	228
638022060	307	41.91	3	304	1	292	3.0e-79	288	COG1234	Ribonuclease BN, tRNA processing enzyme	292
638022062	255	18	10	209	2	201	8.0e-06	44.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638022063	369	26.22	31	369	22	368	5.0e-16	79	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
638022064	1038	34.02	3	1012	2	1009	0.0e+00	808	COG0841	Multidrug efflux pump subunit AcrB	1009
638022068	188	36	8	179	10	183	2.0e-33	135	COG1628	Endonuclease V homolog, UPF0215 family	185
638022069	67	71.64	1	67	1	67	2.0e-24	104	COG1278	Cold shock protein, CspA family	67
638022071	106	39.36	12	104	3	94	1.0e-13	68.1	COG3357	Predicted transcriptional regulator containing an HTH domain fused to a Zn-ribbon	97
638022072	162	22.15	4	143	1	149	1.0e-11	62.8	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
638022073	186	24.2	16	160	6	147	6.0e-11	60.9	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
638022075	323	43.65	1	316	1	313	4.0e-79	288	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
638022077	125	46.55	6	121	1	116	3.0e-30	123	COG3795	Uncharacterized conserved protein	123
638022078	411	53.73	2	411	1	414	8.0e-104	370	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
638022080	467	29.49	21	444	4	401	5.0e-59	222	COG2124	Cytochrome P450	411
638022081	252	60.71	1	252	1	252	3.0e-110	391	COG4604	ABC-type enterochelin transport system, ATPase component	252
638022082	322	54.02	12	322	6	316	2.0e-85	309	COG4605	ABC-type enterochelin transport system, permease component	316
638022083	320	59.38	1	320	4	321	2.0e-101	362	COG4606	ABC-type enterochelin transport system, permease component	321
638022084	301	51.37	8	297	28	319	2.0e-93	335	COG4607	ABC-type enterochelin transport system, periplasmic component	320
638022086	470	21.76	8	408	4	380	1.0e-16	81.7	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
638022092	684	20.94	150	490	23	376	4.0e-22	100	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
638022093	815	18.91	424	815	4	419	8.0e-15	76.3	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
638022094	347	26.2	25	344	14	314	2.0e-46	179	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
638022097	316	36.31	1	311	2	309	3.0e-54	205	COG0657	Acetyl esterase/lipase	312
638022101	447	43.3	4	446	2	446	1.0e-105	376	COG2031	Short chain fatty acids transporter	446
638022102	707	23.83	12	702	2	660	1.0e-26	115	COG1289	Uncharacterized membrane protein YccC	674
638022103	531	30.69	156	528	102	457	8.0e-52	198	COG5002	Signal transduction histidine kinase	459
638022104	310	34.62	195	297	14	117	3.0e-13	69.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638022106	491	29.96	247	470	4	235	2.0e-21	97.1	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
638022109	1967	34.87	1213	1514	59	336	4.0e-40	161	COG0642	Signal transduction histidine kinase	336
638022110	278	28.1	15	278	3	267	5.0e-35	141	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
638022118	252	39.84	8	250	3	248	5.0e-58	217	COG1131	ABC-type multidrug transport system, ATPase component	293
638022119	267	19.05	42	251	73	282	4.0e-06	45.7	COG0842	ABC-type multidrug transport system, permease component	286
638022121	348	30.42	74	313	1	280	7.0e-28	118	COG0515	Serine/threonine protein kinase	384
638022122	434	32.11	14	414	21	418	1.0e-67	250	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
638022124	292	27.45	65	255	1	203	2.0e-11	63.5	COG0412	Dienelactone hydrolase	236
638022126	282	30.57	35	246	4	262	8.0e-21	94.7	COG3483	Tryptophan 2,3-dioxygenase (vermilion)	262
638022128	981	36.43	301	579	65	335	7.0e-43	169	COG0642	Signal transduction histidine kinase	336
638022129	381	30.21	7	378	11	379	1.0e-34	140	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
638022131	614	33.56	315	605	43	334	7.0e-40	159	COG0642	Signal transduction histidine kinase	336
638022143	587	37.98	7	579	1	560	6.0e-119	421	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
638022145	375	57.53	8	374	3	369	9.0e-130	456	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
638022148	208	29.44	7	200	29	217	2.0e-22	99.3	COG0543	NAD(P)H-flavin reductase	252
638022150	589	25.5	67	402	1	345	3.0e-42	166	COG0515	Serine/threonine protein kinase	384
638022154	648	48.57	62	375	47	355	2.0e-89	324	COG4962	Pilus assembly protein, ATPase of CpaF family	355
638022155	225	59.46	4	223	1	222	3.0e-92	331	COG0692	Uracil DNA glycosylase	223
638022156	270	23.1	12	264	15	278	9.0e-13	67.6	COG1946	Acyl-CoA thioesterase	289
638022159	485	23.96	72	476	5	384	9.0e-27	115	COG0006	Xaa-Pro aminopeptidase	384
638022161	942	57.19	18	875	2	804	0.0e+00	1011	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
638022163	278	28.09	8	264	1	292	5.0e-18	85.2	COG0524	Sugar or nucleoside kinase, ribokinase family	311
638022165	327	28.07	37	314	1	280	1.0e-34	141	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
638022166	521	37.34	3	521	6	538	5.0e-74	272	COG1178	ABC-type Fe3+ transport system, permease component	540
638022167	352	45.38	1	347	3	349	1.0e-95	343	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
638022169	275	34.58	1	233	1	228	1.0e-39	156	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
638022174	279	43.33	5	207	2	211	2.0e-39	156	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
638022175	451	34.93	15	449	5	431	7.0e-75	274	COG1030	Membrane-bound serine protease (ClpP class)	436
638022176	436	21.32	41	414	7	379	7.0e-18	85.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638022177	301	22.15	6	301	1	294	1.0e-24	107	COG0583	DNA-binding transcriptional regulator, LysR family	297
638022180	1280	30.56	310	684	12	398	2.0e-59	225	COG1061	Superfamily II DNA or RNA helicase	442
638022184	484	32.26	48	473	5	435	2.0e-72	266	COG0612	Predicted Zn-dependent peptidase	438
638022185	486	28.57	42	462	12	436	4.0e-58	219	COG0612	Predicted Zn-dependent peptidase	438
638022190	602	32.47	40	460	6	387	2.0e-57	217	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638022199	301	32	11	299	15	306	2.0e-20	93.1	COG0679	Predicted permease	311
638022210	269	32.72	1	269	1	265	7.0e-48	184	COG0300	Short-chain dehydrogenase	265
638022211	226	35.41	18	222	7	210	3.0e-28	118	COG0811	Biopolymer transport protein ExbB/TolQ	216
638022212	144	37.78	1	134	2	135	1.0e-22	98.7	COG0848	Biopolymer transport protein ExbD	137
638022213	266	29.41	47	266	56	244	6.0e-09	54.8	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
638022214	920	23.77	261	771	56	584	6.0e-15	76.9	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
638022217	257	29.55	8	257	17	276	2.0e-15	76.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638022219	448	34.76	12	430	14	405	3.0e-77	282	COG2312	Erythromycin esterase homolog	405
638022224	220	20.59	16	212	3	190	7.0e-07	47.7	COG3226	DNA-binding transcriptional regulator YbjK	204
638022232	426	28.1	1	230	8	247	6.0e-22	99	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
638022233	434	46.67	60	416	27	386	2.0e-103	369	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
638022237	328	36.25	1	324	1	326	2.0e-54	206	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
638022242	669	24.01	8	660	114	765	7.0e-72	265	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
638022244	334	31.36	5	328	8	320	2.0e-56	213	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
638022247	871	22.19	260	794	69	642	6.0e-26	113	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
638022252	298	27.86	16	270	6	266	1.0e-16	80.8	COG5607	CHAD domain (function unknown)	283
638022253	176	32.74	4	170	2	164	6.0e-29	120	COG0221	Inorganic pyrophosphatase	171
638022254	488	48.98	1	488	2	488	0.0e+00	603	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
638022255	208	35.75	1	200	1	200	3.0e-34	138	COG0625	Glutathione S-transferase	211
638022256	280	30.62	1	248	3	245	2.0e-31	129	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638022257	183	34.9	9	157	8	155	4.0e-33	134	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
638022262	580	25.32	19	391	2	377	2.0e-42	167	COG0515	Serine/threonine protein kinase	384
638022264	199	30.05	2	187	37	227	2.0e-14	72.5	COG2114	Adenylate cyclase, class 3	227
638022265	215	27.18	10	209	5	209	2.0e-22	99.5	COG0625	Glutathione S-transferase	211
638022267	274	19.86	11	269	13	283	4.0e-07	49	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
638022268	199	24.62	1	181	1	195	4.0e-16	78	COG1011	FMN phosphatase YigB, HAD superfamily	229
638022269	631	27.4	267	631	49	408	3.0e-39	157	COG0840	Methyl-accepting chemotaxis protein	408
638022273	497	34.84	39	309	1	278	8.0e-47	181	COG0515	Serine/threonine protein kinase	384
638022275	474	27.8	221	461	78	292	2.0e-19	90.8	COG2382	Enterochelin esterase or related enzyme	299
638022277	1550	21.58	189	553	11	410	6.0e-20	94.4	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
638022278	220	28.57	11	206	6	200	4.0e-07	48.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638022279	465	32.39	198	465	2	283	9.0e-43	168	COG1408	Predicted phosphohydrolase, MPP superfamily	284
638022280	1466	29.76	220	580	60	468	2.0e-48	189	COG5184	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	476
638022282	361	28.33	63	347	10	298	3.0e-29	122	COG2382	Enterochelin esterase or related enzyme	299
638022283	299	47.16	2	298	2	294	4.0e-88	318	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
638022285	361	32.16	19	359	4	320	5.0e-42	165	COG0142	Geranylgeranyl pyrophosphate synthase	322
638022286	517	33.61	5	492	1	480	3.0e-89	322	COG1233	Phytoene dehydrogenase-related protein	487
638022287	336	40.68	17	310	13	282	9.0e-47	180	COG1562	Phytoene/squalene synthetase	288
638022288	485	28.49	1	485	1	487	3.0e-61	229	COG1233	Phytoene dehydrogenase-related protein	487
638022295	299	32.95	6	93	1	88	2.0e-10	60.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
638022297	1305	23.85	992	1304	5	314	3.0e-22	101	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
638022298	607	41.62	235	603	107	464	1.0e-90	327	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638022302	425	28.57	5	385	19	415	3.0e-15	76.7	COG0531	Amino acid transporter	466
638022303	479	34.51	40	444	4	421	1.0e-81	297	COG0174	Glutamine synthetase	443
638022306	245	38.1	3	240	1	249	2.0e-34	139	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638022307	464	24.18	9	399	5	381	7.0e-33	135	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
638022308	426	37.59	17	421	13	397	3.0e-96	345	COG3844	Kynureninase	407
638022309	338	26.9	26	334	16	293	4.0e-23	102	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
638022311	143	34.56	8	141	7	129	7.0e-25	106	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
638022312	480	44.89	4	480	1	469	0.0e+00	501	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638022314	260	46.09	1	256	4	259	4.0e-71	261	COG0300	Short-chain dehydrogenase	265
638022316	261	36.4	1	260	1	261	1.0e-53	203	COG3971	2-keto-4-pentenoate hydratase	264
638022317	553	38.1	57	541	3	470	1.0e-81	297	COG4529	Uncharacterized NAD(P)/FAD-binding protein YdhS	474
638022321	473	31.21	44	323	1	292	6.0e-43	168	COG0515	Serine/threonine protein kinase	384
638022323	592	26.12	33	590	14	617	2.0e-39	157	COG1297	Uncharacterized membrane protein, oligopeptide transporter (OPT) family	624
638022324	1337	28.07	39	304	1	277	1.0e-31	133	COG0515	Serine/threonine protein kinase	384
638022325	500	45.25	49	401	10	347	1.0e-63	237	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
638022326	228	41.67	98	228	2	128	1.0e-21	96.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
638022327	266	39.48	1	266	1	262	1.0e-60	226	COG3823	Glutamine cyclotransferase	262
638022328	455	51.66	1	448	3	453	0.0e+00	485	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638022329	492	24.93	131	490	12	336	1.0e-38	154	COG0642	Signal transduction histidine kinase	336
638022334	182	42.37	56	172	15	124	3.0e-11	61.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
638022338	277	32.37	92	262	6	175	1.0e-20	94	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638022340	555	40.87	30	551	1	517	0.0e+00	479	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
638022341	389	20.42	13	370	20	376	1.0e-20	94.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638022342	474	55.34	7	473	4	468	0.0e+00	652	COG0362	6-phosphogluconate dehydrogenase	473
638022343	223	40.71	11	221	9	233	2.0e-50	192	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
638022344	514	54.31	23	511	3	480	0.0e+00	633	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
638022346	241	34.86	9	221	1	210	2.0e-24	106	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
638022349	414	25.06	1	409	1	390	1.0e-41	164	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
638022350	1302	20.96	521	1287	171	908	1.0e-27	119	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
638022351	308	27.15	16	284	2	277	3.0e-33	136	COG0515	Serine/threonine protein kinase	384
638022356	311	34.85	55	308	1	250	1.0e-41	163	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
638022357	277	45.32	12	277	9	268	1.0e-82	299	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
638022358	205	61.11	1	198	24	221	8.0e-66	243	COG2011	ABC-type methionine transport system, permease component	222
638022359	330	52.8	1	329	1	339	5.0e-113	401	COG1135	ABC-type methionine transport system, ATPase component	339
638022360	376	47.56	10	371	7	395	4.0e-119	421	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
638022361	366	50.65	1	357	6	392	5.0e-124	437	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
638022362	824	31.97	461	824	2	333	4.0e-57	216	COG0460	Homoserine dehydrogenase	333
638022362	824	37.04	2	458	6	446	1.0e-88	321	COG0527	Aspartokinase	447
638022368	379	31.23	36	358	43	364	1.0e-54	207	COG1858	Cytochrome c peroxidase	364
638022369	470	28.81	47	465	47	438	3.0e-32	133	COG0038	H+/Cl- antiporter ClcA	443
638022370	863	44	62	111	3	51	2.0e-10	61.9	COG3350	Uncharacterized conserved protein, YHS domain	53
638022370	863	48.02	140	860	13	709	0.0e+00	717	COG2217	Cation transport ATPase	713
638022372	363	24.49	24	355	26	367	2.0e-33	136	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
638022374	1040	41.3	1	1024	2	1027	0.0e+00	858	COG3696	Cu/Ag efflux pump CusA	1027
638022375	399	36.13	61	395	41	372	1.0e-22	100	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
638022376	420	25.92	1	419	11	445	5.0e-23	102	COG1538	Outer membrane protein TolC	457
638022379	1066	47.79	12	1049	2	1027	0.0e+00	1084	COG3696	Cu/Ag efflux pump CusA	1027
638022380	393	33.13	75	369	37	355	1.0e-26	114	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
638022381	456	25.18	41	445	22	444	1.0e-23	104	COG1538	Outer membrane protein TolC	457
638022383	321	41.33	14	307	5	300	3.0e-69	255	COG0031	Cysteine synthase	300
638022384	486	29.92	237	486	85	329	2.0e-33	137	COG0642	Signal transduction histidine kinase	336
638022386	351	42.05	6	351	8	350	6.0e-93	334	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
638022387	390	23.34	3	340	1	325	2.0e-26	113	COG0644	Dehydrogenase (flavoprotein)	396
638022388	1455	36.98	31	886	8	810	0.0e+00	701	COG1201	Lhr-like helicase	814
638022389	869	23.6	127	606	25	491	1.0e-19	92.4	COG1404	Serine protease, subtilisin family	508
638022391	187	38.85	25	179	17	173	2.0e-25	108	COG2322	Uncharacterized membrane protein YozB, DUF420 family	177
638022394	476	19.9	18	420	9	358	2.0e-09	57.7	COG4102	Uncharacterized conserved protein, DUF1501 family	418
638022401	462	32.68	1	451	1	421	2.0e-56	213	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
638022403	380	34.48	1	379	8	409	3.0e-51	196	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
638022404	1188	42.01	27	1186	8	1139	0.0e+00	1156	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
638022416	710	27.85	1	447	15	458	2.0e-48	187	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
638022416	710	37.67	482	699	30	251	1.0e-40	161	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
638022417	416	27.66	11	398	2	380	4.0e-32	132	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638022418	378	23.72	5	375	3	381	1.0e-25	110	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638022420	368	24.52	10	366	23	376	4.0e-22	99.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638022421	383	23.81	16	382	17	381	6.0e-30	125	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638022422	411	26.59	1	408	3	381	5.0e-30	125	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638022423	392	23.04	28	390	21	381	4.0e-26	112	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638022424	382	18.72	11	379	4	373	2.0e-14	73.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638022426	506	24.13	15	467	5	464	1.0e-21	97.9	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
638022427	316	27.8	4	274	3	264	9.0e-30	124	COG1216	Glycosyltransferase, GT2 family	305
638022428	304	24.81	1	266	2	266	2.0e-22	99.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
638022430	340	37.14	24	336	10	306	8.0e-47	181	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
638022431	675	20.53	42	556	3	517	9.0e-36	145	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
638022432	376	25.13	22	367	13	380	5.0e-16	79.1	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
638022433	381	26.03	1	377	1	380	1.0e-26	114	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638022434	495	30.28	1	319	2	314	6.0e-47	182	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
638022439	432	57.31	1	416	1	413	0.0e+00	552	COG1004	UDP-glucose 6-dehydrogenase	414
638022440	395	27.82	1	395	9	384	3.0e-22	99.9	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
638022444	182	27.74	5	158	2	155	3.0e-18	84.9	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
638022447	440	53.99	3	440	5	441	0.0e+00	526	COG3724	Succinylarginine dihydrolase	442
638022448	317	37.38	1	301	3	301	9.0e-55	207	COG1560	Lauroyl/myristoyl acyltransferase	308
638022451	247	61.48	1	243	1	243	2.0e-99	355	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
638022452	505	40.67	3	505	1	444	5.0e-112	398	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
638022453	216	29.73	25	202	4	186	9.0e-21	93.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638022455	221	35.58	1	102	1	104	1.0e-19	90.3	COG1544	Ribosome-associated translation inhibitor RaiA	110
638022456	153	33.33	2	152	1	152	5.0e-27	113	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
638022458	153	58.62	1	145	1	145	6.0e-54	203	COG1490	D-Tyr-tRNAtyr deacylase	145
638022460	748	33.04	39	487	19	465	1.0e-70	261	COG2027	D-alanyl-D-alanine carboxypeptidase	470
638022461	165	41.07	3	165	1	167	2.0e-36	145	COG0629	Single-stranded DNA-binding protein	167
638022463	294	37.85	1	285	3	283	7.0e-56	210	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
638022464	343	30.48	11	342	37	402	2.0e-64	239	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
638022465	247	26.62	85	235	7	154	1.0e-18	86.9	COG2236	Hypoxanthine phosphoribosyltransferase	192
638022466	638	37.13	1	473	1	441	4.0e-78	286	COG3276	Selenocysteine-specific translation elongation factor	447
638022468	482	50.11	12	477	6	460	0.0e+00	469	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638022470	519	40.12	8	513	2	470	4.0e-84	305	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
638022471	577	41.15	4	540	1	496	2.0e-130	459	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
638022472	731	38.91	10	724	1	606	2.0e-116	413	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
638022473	100	57.58	1	99	1	99	8.0e-22	95.1	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
638022474	168	39.39	1	165	1	163	9.0e-15	73.3	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
638022475	446	55.09	1	431	2	424	0.0e+00	588	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
638022476	162	44.52	18	161	13	156	8.0e-39	153	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
638022478	516	25.87	239	494	2	279	4.0e-25	109	COG0515	Serine/threonine protein kinase	384
638022479	399	34.18	6	80	1	79	3.0e-12	66.7	COG3830	ACT domain, binds amino acids and other small ligands	90
638022479	399	55.92	176	385	2	212	9.0e-57	214	COG0560	Phosphoserine phosphatase	212
638022482	147	33.33	18	146	20	146	6.0e-20	90.1	COG0071	Molecular chaperone IbpA, HSP20 family	146
638022484	201	47.02	24	191	1	168	6.0e-50	190	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
638022485	278	51.29	7	277	5	275	7.0e-101	360	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
638022486	546	63.48	6	538	1	533	0.0e+00	872	COG0504	CTP synthase (UTP-ammonia lyase)	533
638022487	588	42.11	16	585	2	565	0.0e+00	486	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
638022488	282	41.1	1	280	2	279	4.0e-71	261	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
638022490	246	45.34	3	245	1	246	7.0e-72	263	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
638022491	376	38.56	1	365	3	373	2.0e-85	309	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
638022492	329	37.7	16	313	2	288	5.0e-62	231	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
638022493	478	58.04	15	469	2	459	0.0e+00	639	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
638022495	96	46.15	3	92	2	92	1.0e-19	87.9	COG1534	RNA-binding protein YhbY	97
638022498	256	35.25	8	249	7	250	4.0e-14	72	COG0730	Uncharacterized membrane protein YfcA	258
638022501	505	56.64	4	484	2	481	0.0e+00	662	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
638022503	520	61.28	12	520	16	526	0.0e+00	704	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
638022504	282	36.41	71	254	48	231	8.0e-41	160	COG5031	Ubiquinone biosynthesis protein Coq4	235
638022505	385	30.21	7	234	4	224	4.0e-24	105	COG1994	Zn-dependent protease (includes SpoIVFB)	230
638022509	675	28.81	137	312	51	217	3.0e-24	107	COG0705	Membrane associated serine protease, rhomboid family	228
638022513	1031	24.21	643	1025	24	393	8.0e-22	99	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
638022514	264	42.25	6	262	5	262	2.0e-69	256	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
638022517	457	17.11	26	455	27	435	8.0e-09	55.7	COG4908	Uncharacterized protein, contains a NRPS condensation (elongation) domain	439
638022518	466	48.6	8	465	6	456	0.0e+00	495	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638022519	510	30.68	172	500	1	333	5.0e-34	139	COG0642	Signal transduction histidine kinase	336
638022521	570	29.03	415	567	12	148	3.0e-08	54.4	COG1714	Uncharacterized membrane protein YckC, RDD family	172
638022522	88	39.29	1	84	1	82	9.0e-06	42	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
638022523	244	40	1	237	3	241	2.0e-49	189	COG1385	16S rRNA U1498 N3-methylase RsmE	246
638022524	433	35.48	202	417	19	216	8.0e-28	118	COG2114	Adenylate cyclase, class 3	227
638022525	171	23.93	1	161	1	162	2.0e-07	48.8	COG4539	Uncharacterized membrane protein YGL010W	180
638022526	163	24.82	13	145	11	149	3.0e-11	61.5	COG4539	Uncharacterized membrane protein YGL010W	180
638022527	348	32.79	224	344	1	121	1.0e-16	81.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638022529	288	35.88	4	288	3	299	2.0e-58	219	COG2264	Ribosomal protein L11 methylase PrmA	300
638022531	934	32.53	71	478	19	432	2.0e-76	281	COG0612	Predicted Zn-dependent peptidase	438
638022533	401	38.24	18	401	35	410	3.0e-91	329	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
638022541	354	37.24	5	331	10	341	2.0e-58	219	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
638022542	172	35.04	2	137	1	134	2.0e-24	105	COG1959	DNA-binding transcriptional regulator, IscR family	150
638022543	478	42.73	35	476	1	412	1.0e-123	436	COG0719	Fe-S cluster assembly scaffold protein SufB	412
638022544	262	65.18	1	246	1	243	3.0e-99	354	COG0396	Fe-S cluster assembly ATPase SufC	251
638022545	446	30.09	20	435	7	410	1.0e-76	280	COG0719	Fe-S cluster assembly scaffold protein SufB	412
638022546	407	56.16	2	404	1	404	0.0e+00	499	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
638022547	152	44.2	7	143	3	139	2.0e-30	125	COG0822	NifU homolog involved in Fe-S cluster formation	150
638022548	184	42	84	183	14	110	6.0e-25	107	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
638022549	223	35.68	6	179	2	185	1.0e-26	113	COG0693	Putative intracellular protease/amidase	188
638022550	351	49.36	31	341	6	307	2.0e-81	296	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
638022552	1259	21.24	361	647	98	391	3.0e-06	48.7	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
638022553	612	33.57	20	272	1	278	8.0e-45	175	COG0515	Serine/threonine protein kinase	384
638022554	196	21.94	27	179	25	173	4.0e-09	54.6	COG2203	GAF domain	175
638022556	476	29.71	187	457	68	335	5.0e-30	126	COG0642	Signal transduction histidine kinase	336
638022557	447	52.11	1	440	2	451	0.0e+00	478	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638022561	526	28.26	164	346	2	177	3.0e-11	63.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638022564	137	45.26	1	136	2	136	8.0e-38	149	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
638022565	244	31.14	15	242	5	207	4.0e-26	111	COG0400	Predicted esterase	207
638022566	248	46.47	74	236	1	154	2.0e-45	176	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
638022572	498	47.6	3	494	9	507	0.0e+00	494	COG4262	Predicted spermidine synthase with an N-terminal membrane domain	508
638022574	785	31.45	36	572	3	471	4.0e-86	313	COG3119	Arylsulfatase A or related enzyme	475
638022578	450	49.78	1	449	1	458	3.0e-122	432	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638022581	722	34.13	473	721	5	253	5.0e-43	169	COG1877	Trehalose-6-phosphatase	266
638022581	722	51.06	1	465	14	482	0.0e+00	531	COG0380	Trehalose-6-phosphate synthase	486
638022583	251	39.06	2	248	4	258	3.0e-46	178	COG2162	Arylamine N-acetyltransferase	275
638022586	901	25.39	45	855	19	830	6.0e-96	345	COG0308	Aminopeptidase N	859
638022587	264	24.68	47	201	41	196	6.0e-07	48.3	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
638022592	669	23.53	33	632	60	578	1.0e-23	105	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
638022598	870	35.22	422	782	18	384	2.0e-62	234	COG5545	Predicted P-loop ATPase and inactivated derivatives	517
638022601	471	36.61	63	466	29	401	2.0e-57	216	COG5323	Large terminase phage packaging protein	410
638022622	596	23.99	16	384	1	384	2.0e-30	127	COG0515	Serine/threonine protein kinase	384
638022625	513	57.2	2	512	1	507	0.0e+00	662	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
638022627	385	29.43	16	380	5	432	3.0e-73	269	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
638022628	154	41.29	1	154	1	155	5.0e-41	160	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
638022629	121	42.61	7	121	1	113	5.0e-28	116	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
638022634	477	50.87	6	466	1	455	0.0e+00	505	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638022636	247	20.87	41	244	28	225	2.0e-17	83.1	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
638022637	599	27.49	256	596	69	407	1.0e-39	158	COG0840	Methyl-accepting chemotaxis protein	408
638022638	497	29.9	192	483	34	329	2.0e-36	147	COG0642	Signal transduction histidine kinase	336
638022639	183	25.14	3	181	1	167	3.0e-21	95	COG0262	Dihydrofolate reductase	167
638022643	455	56.21	1	455	1	455	0.0e+00	598	COG1066	Predicted ATP-dependent serine protease	456
638022644	346	55.1	28	339	9	319	2.0e-110	392	COG0502	Biotin synthase or related enzyme	335
638022645	391	51.3	9	387	5	388	3.0e-113	401	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
638022646	227	38.18	9	226	4	222	3.0e-48	185	COG0132	Dethiobiotin synthetase	223
638022648	388	25.38	2	386	1	389	1.0e-40	160	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
638022649	476	25.45	58	384	3	312	4.0e-26	112	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
638022651	597	58.46	1	595	1	606	0.0e+00	832	COG1274	Phosphoenolpyruvate carboxykinase, GTP-dependent	608
638022652	620	19.49	91	597	33	458	1.0e-23	105	COG0471	Di- and tricarboxylate transporter	461
638022653	207	38.67	18	198	12	189	1.0e-29	123	COG4445	tRNA isopentenyl-2-thiomethyl-A-37 hydroxylase MiaE (synthesis of 2-methylthio-cis-ribozeatin)	203
638022654	300	19.13	30	298	5	267	3.0e-09	56.1	COG3393	Predicted acetyltransferase, GNAT family	268
638022659	290	23.53	7	271	1	224	3.0e-15	76.2	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
638022660	531	25.84	318	526	32	213	5.0e-16	79.8	COG2114	Adenylate cyclase, class 3	227
638022662	359	44.25	8	353	3	349	4.0e-100	358	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
638022666	214	36.36	1	206	43	243	9.0e-32	130	COG3279	DNA-binding response regulator, LytR/AlgR family	244
638022669	656	32.49	4	431	1	420	4.0e-83	302	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
638022669	656	38.89	484	637	6	165	2.0e-31	131	COG0066	3-isopropylmalate dehydratase small subunit	191
638022670	356	46.59	3	350	5	348	8.0e-102	364	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
638022671	421	32.06	30	411	3	376	1.0e-61	230	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
638022672	604	20.14	29	450	4	369	2.0e-21	97.9	COG0644	Dehydrogenase (flavoprotein)	396
638022673	709	34.91	125	693	13	567	7.0e-110	391	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
638022675	521	28.06	12	521	1	555	3.0e-70	259	COG2192	Predicted carbamoyl transferase, NodU family	555
638022676	395	23.95	33	256	15	227	1.0e-07	51.5	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
638022677	343	29.39	1	324	5	319	5.0e-29	121	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
638022678	2108	35.58	837	1499	1	642	7.0e-102	366	COG1020	Non-ribosomal peptide synthetase component F	642
638022680	471	30.37	10	464	1	444	4.0e-72	266	COG1232	Protoporphyrinogen oxidase	444
638022681	229	30.41	1	188	6	193	3.0e-24	105	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638022682	220	60.21	30	220	24	214	5.0e-74	270	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
638022683	477	45.08	1	476	1	480	0.0e+00	468	COG0297	Glycogen synthase	487
638022684	304	26.33	9	287	1	282	3.0e-32	132	COG0515	Serine/threonine protein kinase	384
638022688	455	32.02	1	426	1	424	1.0e-75	277	COG1253	Hemolysin or related protein, contains CBS domains	429
638022698	234	56.59	14	216	3	206	3.0e-74	271	COG2360	Leu/Phe-tRNA-protein transferase	221
638022703	671	26.18	51	670	12	607	9.0e-55	208	COG4206	Outer membrane cobalamin receptor protein	608
638022705	362	51.93	17	351	10	342	3.0e-105	375	COG3720	Putative heme degradation protein	349
638022706	300	37.54	1	290	3	293	1.0e-50	193	COG4558	ABC-type hemin transport system, periplasmic component	300
638022707	362	47.46	28	360	9	330	8.0e-50	191	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
638022708	267	53.49	2	259	1	257	2.0e-71	262	COG4559	ABC-type hemin transport system, ATPase component	259
638022709	400	39.16	70	400	2	318	6.0e-73	268	COG2826	Transposase and inactivated derivatives, IS30 family	318
638022727	550	22.4	1	546	3	535	3.0e-57	216	COG2303	Choline dehydrogenase or related flavoprotein	542
638022736	232	46.67	8	231	3	226	1.0e-64	239	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638022738	669	21.74	387	637	17	320	4.0e-07	50.4	COG1858	Cytochrome c peroxidase	364
638022738	669	24.59	33	390	34	381	2.0e-11	65.2	COG3391	DNA-binding beta-propeller fold protein YncE	381
638022741	335	51.66	1	331	2	329	2.0e-112	399	COG0240	Glycerol-3-phosphate dehydrogenase	329
638022743	550	52.79	186	541	3	358	1.0e-105	377	COG2262	50S ribosomal subunit-associated GTPase HflX	411
638022744	377	52.83	9	377	1	369	2.0e-117	416	COG0263	Glutamate 5-kinase	369
638022746	340	25.83	1	332	4	310	6.0e-24	105	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
638022747	309	27.1	5	305	4	304	2.0e-29	123	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
638022749	453	34.32	69	452	35	437	6.0e-64	238	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
638022750	909	61.52	3	908	1	861	0.0e+00	1217	COG1048	Aconitase A	861
638022760	299	30.93	1	277	5	294	2.0e-57	216	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
638022762	267	27.72	6	266	1	282	1.0e-24	107	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638022764	272	44.89	9	231	4	228	1.0e-62	233	COG1131	ABC-type multidrug transport system, ATPase component	293
638022768	653	32.35	31	648	37	677	2.0e-117	416	COG0339	Zn-dependent oligopeptidase	683
638022769	260	38.89	8	258	3	253	4.0e-58	218	COG1099	Predicted metal-dependent hydrolase, TIM-barrel fold	254
638022770	602	45.8	45	600	15	538	0.0e+00	528	COG0405	Gamma-glutamyltranspeptidase	539
638022772	466	54.13	4	459	3	459	0.0e+00	590	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
638022773	611	53.59	1	611	1	597	0.0e+00	790	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
638022775	363	63.54	1	285	1	279	6.0e-86	311	COG0468	RecA/RadA recombinase	279
638022777	185	29.38	10	179	10	186	4.0e-17	81.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638022778	783	51.77	5	752	11	769	0.0e+00	794	COG2183	Transcriptional accessory protein Tex/SPT6	780
638022780	618	23.23	3	595	7	619	5.0e-87	315	COG0326	Molecular chaperone, HSP90 family	623
638022781	279	34.26	41	276	1	247	9.0e-36	144	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
638022783	725	25.55	11	638	1	593	3.0e-25	110	COG1289	Uncharacterized membrane protein YccC	674
638022784	531	27.1	70	365	53	335	8.0e-11	62.2	COG1413	HEAT repeat	335
638022786	312	56.72	5	306	3	307	5.0e-105	374	COG0223	Methionyl-tRNA formyltransferase	307
638022787	307	37.96	1	128	1	136	3.0e-23	102	COG0757	3-dehydroquinate dehydratase	146
638022788	438	22.14	2	125	12	142	6.0e-08	52.6	COG0781	Transcription termination factor NusB	151
638022788	438	38.83	92	436	1	353	4.0e-70	258	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
638022789	302	29.93	1	292	1	290	6.0e-42	164	COG0583	DNA-binding transcriptional regulator, LysR family	297
638022791	365	19.9	1	349	2	400	1.0e-16	81.3	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
638022792	348	35.42	38	306	3	263	6.0e-51	194	COG0300	Short-chain dehydrogenase	265
638022794	373	31.52	54	368	60	389	3.0e-58	219	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
638022799	247	37.8	1	244	6	251	3.0e-44	171	COG0631	Serine/threonine protein phosphatase PrpC	262
638022801	609	28.57	232	609	35	408	2.0e-37	150	COG0840	Methyl-accepting chemotaxis protein	408
638022803	253	41.54	1	250	1	249	1.0e-37	149	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638022808	310	34.95	5	288	3	289	2.0e-58	219	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
638022809	339	24.17	4	241	3	241	2.0e-18	86.7	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
638022812	300	56.25	12	298	4	291	4.0e-115	407	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
638022814	208	34.12	1	208	1	204	3.0e-31	128	COG0625	Glutathione S-transferase	211
638022815	795	44.04	56	791	4	727	0.0e+00	703	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
638022816	1850	18.28	586	1469	151	1009	1.0e-20	97	COG1196	Chromosome segregation ATPase	1163
638022817	177	51.81	1	164	2	167	6.0e-55	206	COG0242	Peptide deformylase	168
638022818	238	47.34	11	217	3	209	4.0e-67	247	COG0177	Endonuclease III	211
638022819	341	49.13	3	341	1	342	3.0e-89	321	COG2008	Threonine aldolase	342
638022821	89	41.57	1	89	2	90	5.0e-17	79	COG0776	Bacterial nucleoid DNA-binding protein	94
638022823	387	20.69	41	323	4	265	8.0e-09	55	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
638022824	287	34.91	5	235	6	222	6.0e-36	145	COG1183	Phosphatidylserine synthase	234
638022825	421	36.29	1	243	2	243	2.0e-53	203	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
638022825	421	46.54	258	416	5	162	4.0e-42	165	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
638022828	342	60.28	1	284	1	279	2.0e-81	296	COG0468	RecA/RadA recombinase	279
638022829	461	50	11	408	4	400	5.0e-117	415	COG1252	NADH dehydrogenase, FAD-containing subunit	405
638022830	547	50.2	14	509	1	490	0.0e+00	527	COG0606	Predicted ATPase with chaperone activity	490
638022833	166	32.65	1	147	1	137	2.0e-21	95.3	COG0848	Biopolymer transport protein ExbD	137
638022834	138	32.61	1	138	2	136	5.0e-22	96.8	COG0848	Biopolymer transport protein ExbD	137
638022835	227	33.66	14	215	17	211	1.0e-28	119	COG0811	Biopolymer transport protein ExbB/TolQ	216
638022836	250	24.23	25	249	36	244	7.0e-10	57.8	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
638022839	514	24.13	28	427	1	420	4.0e-30	126	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
638022844	192	46.88	5	192	8	199	5.0e-39	154	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
638022845	433	43.09	22	392	5	375	4.0e-96	345	COG0116	23S rRNA G2445 N2-methylase RlmL	381
638022846	96	29.11	1	79	1	79	8.0e-09	51.9	COG1359	Quinol monooxygenase YgiN	100
638022847	1063	23.08	91	749	26	632	7.0e-70	259	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
638022849	95	51.58	1	95	1	95	6.0e-22	95.7	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
638022850	486	55.58	1	485	2	475	0.0e+00	501	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
638022851	479	56.85	1	479	1	482	0.0e+00	702	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
638022853	320	32.32	6	319	4	322	8.0e-59	220	COG3491	Isopenicillin N synthase and related dioxygenases	322
638022854	693	32.04	58	319	1	278	5.0e-46	179	COG0515	Serine/threonine protein kinase	384
638022856	104	47.57	3	104	1	103	2.0e-27	114	COG0261	Ribosomal protein L21	103
638022857	91	60.92	1	87	1	87	4.0e-28	116	COG0211	Ribosomal protein L27	87
638022858	485	55.86	1	365	1	366	0.0e+00	502	COG0536	GTPase involved in cell partioning and DNA repair	369
638022860	219	28.88	29	214	29	211	7.0e-20	90.8	COG2834	Outer membrane lipoprotein-sorting protein	211
638022863	476	40.09	7	444	3	437	4.0e-124	438	COG0621	tRNA A37 methylthiotransferase MiaB	437
638022865	165	49.09	1	165	4	165	1.0e-39	156	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
638022866	546	41.74	2	544	9	555	0.0e+00	525	COG0595	mRNA degradation ribonuclease J1/J2	555
638022867	1175	28.62	292	576	2	281	5.0e-35	144	COG0515	Serine/threonine protein kinase	384
638022869	448	19.17	62	298	51	267	1.0e-12	68.1	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
638022871	966	30.85	22	597	137	774	8.0e-89	322	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
638022873	180	33.09	10	144	1	132	3.0e-17	81.5	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
638022882	492	31.38	11	369	5	379	3.0e-48	186	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
638022884	357	24.68	32	312	46	354	3.0e-19	89.5	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
638022888	435	29.77	32	395	22	405	8.0e-30	125	COG1404	Serine protease, subtilisin family	508
638022890	235	42.33	11	225	1	212	3.0e-55	208	COG1515	Deoxyinosine 3'endonuclease (endonuclease V)	212
638022891	781	21.42	9	560	2	538	7.0e-32	132	COG2303	Choline dehydrogenase or related flavoprotein	542
638022892	190	28.12	60	186	5	132	4.0e-10	58	COG5502	Uncharacterized conserved protein, DUF2267 family	135
638022897	222	27.22	53	210	37	175	4.0e-08	52	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638022901	255	31.52	71	254	1	180	1.0e-10	60.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638022902	161	21.13	12	151	3	140	5.0e-09	53.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
638022903	783	43.72	13	691	1	649	0.0e+00	550	COG0210	Superfamily I DNA or RNA helicase	655
638022905	363	24.23	84	356	18	302	8.0e-14	71.8	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
638022906	355	41.67	2	335	4	339	8.0e-80	291	COG1816	Adenosine deaminase	345
638022907	259	40.77	3	256	1	251	9.0e-35	140	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638022908	474	32.95	48	473	19	431	2.0e-60	226	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
638022911	409	48.66	1	409	3	388	0.0e+00	463	COG0448	ADP-glucose pyrophosphorylase	393
638022914	342	30.18	1	322	1	311	7.0e-40	158	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638022915	1470	29.47	1249	1449	50	253	2.0e-18	89.2	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
638022915	1470	30.33	559	1099	14	597	5.0e-96	346	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
638022917	221	30.84	4	217	6	202	2.0e-31	128	COG0560	Phosphoserine phosphatase	212
638022918	326	25.81	1	324	1	312	2.0e-35	143	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638022920	1013	41.31	23	1010	2	888	0.0e+00	829	COG3280	Maltooligosyltrehalose synthase	889
638022921	713	52.4	8	709	14	691	0.0e+00	825	COG1523	Pullulanase/glycogen debranching enzyme	697
638022922	316	27.95	62	311	14	254	7.0e-39	154	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
638022923	128	48.8	4	128	2	126	4.0e-39	153	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
638022924	364	38.89	5	343	3	317	9.0e-85	307	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
638022932	333	54.77	17	214	13	210	5.0e-62	231	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
638022933	473	35.14	7	148	4	146	5.0e-19	89.4	COG4276	Ligand-binding SRPBCC domain	153
638022933	473	43.14	166	463	1	296	2.0e-79	290	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
638022934	309	39.09	1	304	4	293	9.0e-68	250	COG1131	ABC-type multidrug transport system, ATPase component	293
638022935	240	23.59	1	182	2	196	6.0e-06	44.7	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
638022940	706	29.39	361	706	2	334	4.0e-43	170	COG0642	Signal transduction histidine kinase	336
638022941	504	23.28	26	384	1	375	5.0e-36	146	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
638022941	504	31.25	422	498	11	90	4.0e-10	60	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
638022943	224	35.11	1	214	51	273	5.0e-44	171	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
638022945	465	29.91	17	436	20	444	2.0e-36	147	COG0531	Amino acid transporter	466
638022947	429	29.41	39	419	32	393	7.0e-53	201	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
638022949	158	42.04	1	157	1	156	2.0e-35	141	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
638022950	174	20.71	3	169	2	165	3.0e-06	45.2	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
638022951	184	46.74	1	177	2	182	6.0e-63	233	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
638022952	531	39.92	14	520	32	545	1.0e-111	397	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
638022954	297	36.63	5	287	1	303	3.0e-57	215	COG1984	Allophanate hydrolase subunit 2	314
638022955	432	36.92	236	432	2	213	1.0e-36	148	COG2049	Allophanate hydrolase subunit 1	223
638022955	432	42.06	4	238	1	251	2.0e-54	206	COG1540	Lactam utilization protein B (function unknown)	252
638022957	378	32.84	1	374	1	400	1.0e-70	260	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
638022958	306	54.03	4	298	3	299	8.0e-102	363	COG0031	Cysteine synthase	300
638022959	281	46.34	96	259	4	162	4.0e-42	165	COG1045	Serine acetyltransferase	194
638022960	552	39.92	14	536	1	524	0.0e+00	461	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
638022961	133	39.17	1	120	1	120	6.0e-21	93	COG3070	Transcriptional regulator of competence genes, TfoX/Sxy family	121
638022962	311	34.77	1	298	1	297	9.0e-34	137	COG0583	DNA-binding transcriptional regulator, LysR family	297
638022964	313	30.84	22	306	2	306	5.0e-40	158	COG0515	Serine/threonine protein kinase	384
638022966	156	38.73	11	150	18	151	5.0e-16	77.2	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
638022967	596	22.51	77	278	9	229	2.0e-06	48	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
638022968	395	26.18	8	346	15	342	5.0e-31	128	COG0628	Predicted PurR-regulated permease PerM	355
638022970	415	24.26	282	413	8	143	2.0e-13	70.6	COG3610	Uncharacterized membrane protein YjjB, DUF3815 family	156
638022970	415	30.21	21	253	16	250	6.0e-33	135	COG2966	Uncharacterized membrane protein YjjP, DUF1212 family	250
638022973	266	40.74	31	263	5	244	1.0e-53	203	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
638022975	274	29.32	5	254	4	265	4.0e-24	105	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
638022976	189	60.11	1	186	3	189	1.0e-78	285	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
638022977	484	43.53	28	478	1	455	3.0e-124	439	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
638022981	525	28.42	8	380	3	377	9.0e-48	184	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
638022982	315	25.47	1	303	1	306	1.0e-21	97.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638022983	314	21.39	80	271	41	229	1.0e-12	67.6	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
638022984	316	40.98	8	305	4	293	4.0e-70	258	COG1131	ABC-type multidrug transport system, ATPase component	293
638022985	341	32.18	140	340	80	281	1.0e-16	81.1	COG0842	ABC-type multidrug transport system, permease component	286
638022987	388	25.77	46	388	48	391	1.0e-33	137	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
638022990	1237	27.97	26	556	2	531	4.0e-67	250	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
638022992	430	20.77	1	429	3	407	3.0e-24	106	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
638022994	5544	41.2	3386	4043	1	642	1.0e-127	454	COG1020	Non-ribosomal peptide synthetase component F	642
638022997	332	22.92	12	317	28	352	2.0e-26	113	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
638023001	444	30.54	16	440	26	451	3.0e-52	199	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
638023004	68	68.66	1	67	1	67	2.0e-22	97.5	COG1278	Cold shock protein, CspA family	67
638023007	804	23.3	119	748	121	758	2.0e-46	181	COG0417	DNA polymerase elongation subunit (family B)	792
638023010	478	27.15	36	470	4	433	4.0e-54	206	COG0612	Predicted Zn-dependent peptidase	438
638023011	473	31.57	54	459	18	432	8.0e-65	241	COG0612	Predicted Zn-dependent peptidase	438
638023017	410	24.23	69	388	40	422	4.0e-27	116	COG3325	Chitinase, GH18 family	441
638023020	209	34.43	11	190	4	184	6.0e-25	107	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638023023	655	20.13	14	453	3	443	4.0e-25	110	COG0531	Amino acid transporter	466
638023026	366	31.58	13	343	2	315	3.0e-44	172	COG1088	dTDP-D-glucose 4,6-dehydratase	340
638023027	690	23.6	80	469	54	439	5.0e-17	83.2	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
638023030	151	27.85	1	151	1	150	7.0e-20	90	COG1959	DNA-binding transcriptional regulator, IscR family	150
638023031	318	29.3	6	316	2	282	1.0e-23	104	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638023032	309	38.67	118	288	38	210	1.0e-16	80.7	COG3714	Uncharacterized membrane protein YhhN	212
638023033	177	48.54	3	167	2	171	5.0e-41	160	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
638023036	523	34.6	6	489	2	489	3.0e-93	335	COG2272	Carboxylesterase type B	491
638023040	300	27.92	63	300	44	279	4.0e-26	112	COG1398	Fatty-acid desaturase	289
638023041	249	28.79	19	216	4	201	3.0e-11	62.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638023046	122	36.45	6	112	3	107	5.0e-15	73.5	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
638023048	187	35.8	12	183	1	176	6.0e-22	97.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638023052	237	23.03	86	222	13	164	9.0e-09	53.9	COG2453	Protein-tyrosine phosphatase	180
638023053	281	25.2	34	274	24	236	7.0e-12	64.6	COG0412	Dienelactone hydrolase	236
638023054	373	33.77	63	364	35	328	2.0e-46	180	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
638023058	692	47.65	17	690	11	700	0.0e+00	571	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
638023061	329	24.7	12	323	4	314	4.0e-23	102	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638023063	631	25.25	124	611	1	450	1.0e-52	201	COG0277	FAD/FMN-containing dehydrogenase	459
638023065	340	23.61	19	323	35	313	3.0e-25	109	COG1899	Deoxyhypusine synthase	318
638023066	388	25.32	99	387	17	332	2.0e-25	110	COG0642	Signal transduction histidine kinase	336
638023067	224	37.83	1	223	1	229	7.0e-44	170	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638023069	759	24.82	210	741	50	602	4.0e-40	159	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
638023070	301	37.62	1	298	1	297	2.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
638023071	195	52.24	66	195	1	132	5.0e-40	157	COG5649	Uncharacterized protein	132
638023075	869	21.03	199	861	27	600	5.0e-19	90.4	COG4206	Outer membrane cobalamin receptor protein	608
638023077	314	31.58	40	303	13	257	2.0e-39	156	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
638023078	349	28.86	27	319	6	279	2.0e-16	80.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638023079	144	29.2	13	143	5	129	2.0e-13	68.8	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
638023081	819	25.5	546	818	118	419	7.0e-19	89.8	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
638023085	377	18.66	103	369	62	296	1.0e-11	64.7	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
638023087	437	20.54	4	405	22	342	8.0e-28	118	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
638023096	1049	28.71	87	369	2	289	1.0e-38	156	COG0515	Serine/threonine protein kinase	384
638023097	304	35.22	2	296	1	297	1.0e-28	120	COG0583	DNA-binding transcriptional regulator, LysR family	297
638023098	312	26.02	74	304	15	246	8.0e-19	87.9	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
638023101	282	31.75	31	282	1	231	9.0e-20	91.2	COG2801	Transposase InsO and inactivated derivatives	232
638023104	117	25.23	12	113	17	123	1.0e-07	48.8	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
638023105	289	23.02	136	260	2	127	3.0e-09	56	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638023112	293	36.12	2	289	1	297	8.0e-33	134	COG0583	DNA-binding transcriptional regulator, LysR family	297
638023114	388	20.77	4	338	8	363	1.0e-09	57.6	COG2311	Uncharacterized membrane protein YeiB	394
638023115	98	55.13	14	91	1	78	9.0e-21	91.5	COG3811	Uncharacterized protein YjhX, UPF0386 family	85
638023121	386	26.1	21	383	10	379	3.0e-18	86.8	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
638023128	478	20.46	17	447	1	400	1.0e-25	111	COG2124	Cytochrome P450	411
638023131	498	38.6	34	485	8	453	6.0e-91	328	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
638023132	212	46.15	1	195	37	228	2.0e-62	232	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
638023136	159	49.36	1	154	1	156	7.0e-53	199	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
638023137	718	24.29	65	713	45	720	4.0e-48	186	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
638023139	255	46.25	6	253	2	251	5.0e-47	181	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638023141	351	37.69	25	337	4	315	4.0e-79	288	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
638023142	314	30.33	13	308	5	297	5.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
638023143	343	36.24	6	343	1	350	2.0e-61	229	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
638023145	171	38.94	50	161	14	125	5.0e-10	57.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
638023151	185	20.11	3	182	1	162	1.0e-09	56.5	COG0262	Dihydrofolate reductase	167
638023171	405	25.07	18	382	14	350	1.0e-18	88.1	COG1566	Multidrug resistance efflux pump	352
638023172	909	26.71	304	863	14	566	2.0e-58	221	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
638023173	703	24.2	190	702	15	522	9.0e-43	169	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
638023174	499	27.21	59	494	16	450	3.0e-37	150	COG1538	Outer membrane protein TolC	457
638023176	336	27.39	16	321	20	313	8.0e-26	111	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
638023180	247	25.42	57	225	19	188	2.0e-06	46.1	COG2801	Transposase InsO and inactivated derivatives	232
638023181	453	33.33	2	401	1	366	1.0e-46	180	COG5659	SRSO17 transposase	385
638023182	184	21.84	10	180	8	162	5.0e-15	74.2	COG0262	Dihydrofolate reductase	167
638023189	1656	43.1	1	1636	1	1518	0.0e+00	1559	COG4889	Predicted helicase	1518
638023191	204	29.86	54	192	14	152	2.0e-07	49.7	COG1714	Uncharacterized membrane protein YckC, RDD family	172
638023196	334	34.18	4	309	3	316	5.0e-52	198	COG5351	Uncharacterized protein	367
638023200	129	44.07	10	125	4	120	2.0e-17	81.1	COG2105	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family	120
638023226	427	25.75	33	357	25	340	4.0e-16	79.6	COG3500	Phage protein D	350
638023245	427	24.89	9	208	9	226	2.0e-25	110	COG0338	Site-specific DNA-adenine methylase	274
638023249	674	27.73	94	597	6	467	4.0e-56	213	COG5518	Bacteriophage capsid portal protein	492
638023258	391	23.44	9	245	1	253	8.0e-10	58.5	COG2887	RecB family exonuclease	269
638023263	938	32.48	608	932	69	414	2.0e-46	181	COG1061	Superfamily II DNA or RNA helicase	442
638023268	515	36.44	12	234	1	210	5.0e-29	122	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
638023276	662	26.67	18	279	1	270	3.0e-32	133	COG0515	Serine/threonine protein kinase	384
638023285	597	44.67	1	594	5	589	6.0e-113	401	COG5293	Uncharacterized protein YydD, contains DUF2326 domain	591
638023289	427	38.76	133	425	49	354	2.0e-63	236	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
638023290	303	35.69	8	301	2	312	6.0e-64	237	COG1619	Muramoyltetrapeptide carboxypeptidase LdcA (peptidoglycan recycling)	313
638023291	393	30.05	21	382	58	386	1.0e-27	118	COG1680	CubicO group peptidase, beta-lactamase class C family	390
638023292	474	40.94	1	468	7	459	4.0e-113	401	COG0773	UDP-N-acetylmuramate-alanine ligase	459
638023293	136	27.52	5	112	20	127	3.0e-11	60.7	COG0526	Thiol-disulfide isomerase or thioredoxin	127
638023294	273	45.67	12	260	7	260	1.0e-63	236	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
638023295	204	32.85	1	202	2	206	2.0e-28	118	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
638023301	490	24.39	174	416	1	227	1.0e-12	68.1	COG3063	Tfp pilus assembly protein PilF	250
638023305	195	28.65	7	180	5	170	8.0e-15	73.8	COG2229	Signal recognition particle receptor subunit beta, a GTPase	187
638023306	159	23.93	14	129	4	119	2.0e-06	45.6	COG2018	Predicted regulator of Ras-like GTPase activity, Roadblock/LC7/MglB family	119
638023309	646	25	25	357	2	338	1.0e-40	161	COG0515	Serine/threonine protein kinase	384
638023310	197	54.31	1	197	2	198	3.0e-73	267	COG0353	Recombinational DNA repair protein RecR	198
638023311	105	35.35	1	99	2	100	3.0e-17	80.3	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
638023312	402	47.58	1	391	1	393	1.0e-119	423	COG2812	DNA polymerase III, gamma/tau subunits	515
638023316	154	53.74	1	146	6	152	2.0e-47	181	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
638023320	426	58.41	1	425	1	427	0.0e+00	554	COG0172	Seryl-tRNA synthetase	429
638023321	1628	24.88	1362	1564	20	228	7.0e-11	64.2	COG3063	Tfp pilus assembly protein PilF	250
638023322	437	25.27	3	435	2	442	1.0e-39	157	COG1232	Protoporphyrinogen oxidase	444
638023323	236	21.46	1	232	1	222	5.0e-11	61.7	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
638023325	314	28.93	88	274	42	226	2.0e-18	86.5	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
638023326	307	21.94	5	302	3	302	5.0e-26	111	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638023331	241	40.18	1	223	1	224	7.0e-51	193	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
638023333	320	48.58	4	320	1	305	8.0e-90	323	COG0492	Thioredoxin reductase	305
638023334	394	41.79	6	390	9	394	2.0e-98	352	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
638023335	164	55.86	1	144	13	157	9.0e-49	186	COG0315	Molybdenum cofactor biosynthesis enzyme	157
638023337	274	34.43	3	274	2	269	1.0e-36	146	COG2912	Regulator of sirC expression, contains transglutaminase-like and TPR domains	269
638023342	147	40.74	14	147	9	139	6.0e-28	116	COG1832	Predicted CoA-binding protein	140
638023347	1152	40.28	307	1151	1	842	0.0e+00	784	COG1410	Methionine synthase I, cobalamin-binding domain	842
638023347	1152	50.16	1	306	5	311	3.0e-93	337	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
638023352	390	44.83	35	381	9	340	7.0e-95	341	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
638023353	275	32.45	10	272	3	265	6.0e-51	194	COG0300	Short-chain dehydrogenase	265
638023355	288	42.41	29	285	11	256	2.0e-72	266	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
638023356	265	38.52	1	257	3	255	2.0e-66	245	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
638023362	190	42.86	1	188	2	190	1.0e-46	179	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
638023363	437	33.05	317	431	12	128	1.0e-10	61.1	COG3824	Predicted Zn-dependent protease, minimal metalloprotease (MMP)-like domain	136
638023364	398	38.78	14	396	2	391	3.0e-74	272	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
638023368	691	45.94	4	646	1	647	0.0e+00	556	COG0210	Superfamily I DNA or RNA helicase	655
638023369	151	54.86	7	149	2	143	1.0e-46	178	COG0102	Ribosomal protein L13	148
638023370	133	64.8	9	133	6	130	1.0e-48	184	COG0103	Ribosomal protein S9	130
638023371	491	53.11	24	377	3	353	1.0e-128	453	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
638023373	168	32.52	1	162	9	167	1.0e-12	66.1	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
638023374	261	28.46	11	259	3	247	4.0e-31	128	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
638023376	240	25.11	2	227	32	247	1.0e-12	66.9	COG3063	Tfp pilus assembly protein PilF	250
638023378	352	43.36	11	347	7	341	1.0e-76	280	COG0709	Selenophosphate synthase	346
638023379	269	35.71	12	249	26	228	8.0e-43	167	COG0860	N-acetylmuramoyl-L-alanine amidase	231
638023380	237	48.32	1	237	8	230	5.0e-60	224	COG0689	Ribonuclease PH	230
638023381	197	51.31	6	194	3	190	1.0e-58	219	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
638023389	425	37.56	1	423	1	424	2.0e-75	276	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
638023390	206	72.25	6	196	4	194	2.0e-84	305	COG0740	ATP-dependent protease ClpP, protease subunit	200
638023391	427	70.83	17	423	1	408	0.0e+00	669	COG1219	ATP-dependent protease Clp, ATPase subunit	408
638023392	689	36.5	19	676	1	648	0.0e+00	464	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
638023393	817	62.81	10	784	2	774	0.0e+00	1121	COG0466	ATP-dependent Lon protease, bacterial type	782
638023394	526	24.95	2	490	48	536	2.0e-50	194	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
638023395	294	26.75	1	290	2	314	1.0e-23	103	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
638023398	181	42.08	1	179	10	192	3.0e-39	154	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
638023399	85	45	2	81	1	77	2.0e-18	84.2	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
638023400	106	50	2	101	1	102	2.0e-35	140	COG0278	Glutaredoxin-related protein	105
638023402	516	28.29	99	497	23	384	7.0e-47	182	COG0006	Xaa-Pro aminopeptidase	384
638023403	254	29.72	1	244	2	246	7.0e-36	144	COG1385	16S rRNA U1498 N3-methylase RsmE	246
638023404	396	29.57	7	187	30	213	4.0e-26	112	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
638023406	199	33.7	12	190	2	182	9.0e-25	106	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638023408	342	36.51	33	337	74	383	4.0e-70	258	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
638023409	231	37.44	21	217	7	202	1.0e-37	150	COG1573	Uracil-DNA glycosylase	202
638023410	253	40.56	1	244	5	252	2.0e-42	166	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638023411	381	53.06	1	381	6	396	0.0e+00	497	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
638023416	146	44.3	1	146	14	158	9.0e-28	115	COG2030	Acyl dehydratase	159
638023417	455	51.46	3	310	1	300	4.0e-102	365	COG0031	Cysteine synthase	300
638023418	346	32.23	27	342	16	343	2.0e-40	160	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
638023419	342	27.76	1	332	2	320	3.0e-60	225	COG1208	NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins	358
638023420	254	38.67	1	251	6	251	3.0e-60	225	COG0631	Serine/threonine protein phosphatase PrpC	262
638023421	118	37.5	21	118	21	123	3.0e-16	77.3	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
638023422	167	44.08	9	159	3	154	1.0e-46	179	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
638023427	331	50.3	1	331	1	334	9.0e-114	403	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
638023428	283	43.02	12	274	1	257	3.0e-69	255	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
638023430	214	38.35	4	200	5	210	1.0e-42	166	COG1428	Deoxyadenosine/deoxycytidine kinase	216
638023431	305	59.7	4	271	1	268	9.0e-105	373	COG0413	Ketopantoate hydroxymethyltransferase	268
638023432	292	54.77	5	284	3	283	5.0e-97	347	COG0414	Panthothenate synthetase	285
638023433	162	50.67	13	162	2	151	7.0e-48	183	COG0691	tmRNA-binding protein	153
638023435	569	27.71	5	376	2	384	5.0e-36	146	COG0515	Serine/threonine protein kinase	384
638023436	112	36.26	17	107	6	94	8.0e-17	78.8	COG3536	Uncharacterized conserved protein, DUF971 family	120
638023437	568	34.22	265	560	24	321	4.0e-54	206	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
638023440	267	45.22	1	265	2	263	8.0e-53	200	COG0388	Predicted amidohydrolase	274
638023441	161	48.37	9	161	5	153	5.0e-38	150	COG0779	Ribosome maturation factor RimP	153
638023442	566	55.08	191	376	1	181	1.0e-46	181	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
638023444	1072	57	569	1072	2	508	0.0e+00	635	COG0532	Translation initiation factor IF-2, a GTPase	509
638023445	202	36.56	1	93	1	93	1.0e-16	79.9	COG1550	Uncharacterized conserved protein YlxP, DUF503 family	95
638023446	119	37.29	1	117	1	117	1.0e-26	111	COG0858	Ribosome-binding factor A	118
638023447	289	39.79	2	289	15	270	3.0e-63	235	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
638023448	89	65.17	1	89	1	89	1.0e-25	107	COG0184	Ribosomal protein S15P/S13E	89
638023449	722	56.85	1	692	4	690	0.0e+00	873	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
638023451	338	30.08	91	331	25	266	4.0e-31	128	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
638023452	151	55.86	7	151	4	147	1.0e-45	175	COG0756	dUTPase	148
638023453	842	20.26	55	405	2	382	5.0e-33	136	COG0515	Serine/threonine protein kinase	384
638023453	842	22.35	657	841	51	314	2.0e-14	74.8	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
638023454	340	28	31	316	12	306	4.0e-24	105	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
638023455	437	49.77	1	434	1	437	0.0e+00	503	COG0015	Adenylosuccinate lyase	438
638023456	319	34.31	26	294	8	247	4.0e-56	211	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
638023458	243	33.47	5	242	3	241	4.0e-39	154	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
638023460	419	35.01	33	363	19	347	6.0e-56	212	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
638023464	178	32.11	50	158	22	127	2.0e-12	65.7	COG0526	Thiol-disulfide isomerase or thioredoxin	127
638023466	639	30.22	425	605	10	190	9.0e-30	125	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
638023467	538	22.17	63	479	23	428	2.0e-39	157	COG0612	Predicted Zn-dependent peptidase	438
638023468	454	26.5	24	450	7	435	4.0e-57	215	COG0612	Predicted Zn-dependent peptidase	438
638023471	341	32.6	2	314	1	318	4.0e-53	201	COG5351	Uncharacterized protein	367
638023472	354	21.05	7	271	7	303	2.0e-06	47.2	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
638023477	436	28.52	17	303	31	326	4.0e-27	116	COG3344	Retron-type reverse transcriptase	328
638023487	148	47.24	21	147	10	136	9.0e-25	106	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
638023488	224	37.3	6	187	15	199	4.0e-31	128	COG1484	DNA replication protein DnaC	254
638023493	293	25.11	57	275	19	230	3.0e-11	62.7	COG2801	Transposase InsO and inactivated derivatives	232
638023499	303	33.9	7	300	1	291	3.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
638023506	470	26.72	3	360	8	383	3.0e-38	153	COG1680	CubicO group peptidase, beta-lactamase class C family	390
638023507	372	44.51	11	337	2	314	2.0e-80	293	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
638023510	331	26.6	16	327	35	318	3.0e-36	145	COG1899	Deoxyhypusine synthase	318
638023514	304	27.97	7	267	3	244	2.0e-15	76.9	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
638023518	971	19.01	139	762	56	734	3.0e-17	84.6	COG1643	HrpA-like RNA helicase	845
638023520	701	25.43	314	650	20	354	2.0e-29	125	COG1680	CubicO group peptidase, beta-lactamase class C family	390
638023521	205	59.47	12	201	2	184	1.0e-47	182	COG3644	Uncharacterized protein	194
638023522	341	44.84	1	338	4	339	9.0e-94	337	COG2130	NADPH-dependent curcumin reductase CurA	340
638023524	295	26.46	9	292	1	285	3.0e-25	109	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
638023526	654	29.38	10	305	2	317	1.0e-41	164	COG0515	Serine/threonine protein kinase	384
638023529	587	46.09	261	585	109	453	1.0e-88	320	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638023532	386	28.07	212	377	32	201	2.0e-10	60.7	COG0666	Ankyrin repeat	235
638023534	175	38.41	1	163	28	190	7.0e-31	127	COG3812	Uncharacterized protein	193
638023538	512	30.42	31	313	1	278	1.0e-31	131	COG4584	Transposase	278
638023539	253	30.92	1	246	5	253	1.0e-40	160	COG1484	DNA replication protein DnaC	254
638023546	597	25.22	16	333	1	329	2.0e-31	131	COG0515	Serine/threonine protein kinase	384
638023547	405	25.46	50	366	1	282	9.0e-16	78.3	COG0515	Serine/threonine protein kinase	384
638023549	321	44.48	6	305	3	305	4.0e-70	258	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
638023550	231	31.31	1	210	2	211	1.0e-32	133	COG2085	Predicted dinucleotide-binding enzyme	211
638023554	288	30.82	5	154	19	177	1.0e-20	94	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638023556	571	21	9	366	20	383	1.0e-15	78.5	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
638023558	502	41.28	118	501	23	396	2.0e-81	296	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
638023570	328	34.07	51	319	46	312	7.0e-41	161	COG0657	Acetyl esterase/lipase	312
638023573	233	29.17	66	232	18	181	5.0e-12	64.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638023576	218	40	40	213	4	177	2.0e-24	105	COG1268	Biotin transporter BioY	184
638023578	494	29.1	9	457	7	435	9.0e-76	278	COG3303	Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit	501
638023579	164	22.56	12	148	16	178	3.0e-12	64.6	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
638023581	405	21.86	20	378	28	386	1.0e-12	67.9	COG2814	Predicted arabinose efflux permease, MFS family	394
638023584	261	30.25	137	254	1	119	5.0e-16	78.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638023585	311	29.97	11	295	7	286	2.0e-06	47.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
638023590	325	21.51	76	321	75	305	9.0e-12	64.6	COG3021	Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily	309
638023591	580	41.09	2	545	7	542	6.0e-100	358	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
638023594	292	55.33	3	292	1	282	4.0e-102	364	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
638023600	341	31.56	30	311	14	276	6.0e-42	165	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
638023601	419	21.41	11	400	9	410	6.0e-08	52.5	COG0738	Fucose permease	422
638023602	182	33.15	2	182	6	186	5.0e-25	107	COG3226	DNA-binding transcriptional regulator YbjK	204
638023604	617	27.24	19	587	20	495	2.0e-58	220	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
638023605	225	14.08	13	210	1	205	4.0e-16	78.3	COG1335	Nicotinamidase-related amidase	205
638023606	213	16.02	15	212	1	205	4.0e-21	94.9	COG1335	Nicotinamidase-related amidase	205
638023607	189	40.56	7	180	3	175	1.0e-31	129	COG0431	NAD(P)H-dependent FMN reductase	184
638023608	317	37.16	1	316	1	326	6.0e-47	181	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
638023614	482	18.34	27	474	1	458	6.0e-32	132	COG0277	FAD/FMN-containing dehydrogenase	459
638023615	721	32.08	118	523	27	443	3.0e-47	183	COG2319	WD40 repeat	466
638023617	394	55.08	1	392	2	385	0.0e+00	480	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
638023618	277	61.9	2	274	9	281	4.0e-88	317	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
638023619	309	39.01	37	308	18	296	6.0e-57	214	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
638023623	496	29.17	14	354	1	353	4.0e-44	172	COG0515	Serine/threonine protein kinase	384
638023628	583	67.24	1	409	1	402	0.0e+00	464	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
638023629	1155	30.74	154	447	1	277	2.0e-63	238	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
638023629	1155	31.5	18	144	12	137	2.0e-27	119	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
638023630	327	50.46	4	321	2	321	2.0e-91	329	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
638023631	730	61.54	595	724	10	139	2.0e-43	171	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
638023631	730	61.91	34	562	17	548	0.0e+00	720	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
638023632	626	29.82	18	489	3	505	1.0e-78	287	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
638023633	255	43.06	8	150	6	140	1.0e-32	133	COG0328	Ribonuclease HI	154
638023634	213	30.81	7	203	5	212	1.0e-30	126	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
638023635	357	37.29	6	354	4	325	6.0e-54	204	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
638023636	809	19.35	416	807	1	417	4.0e-16	80.6	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
638023641	361	38.71	30	332	7	300	1.0e-70	260	COG1162	Putative ribosome biogenesis GTPase RsgA	301
638023642	455	28.79	25	324	5	320	2.0e-24	107	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
638023646	819	31.75	466	816	3	329	1.0e-67	252	COG0460	Homoserine dehydrogenase	333
638023646	819	41.47	1	461	3	445	2.0e-112	400	COG0527	Aspartokinase	447
638023648	341	37.54	6	337	5	326	3.0e-57	215	COG0306	Phosphate/sulfate permease	326
638023649	208	28.91	4	206	7	216	1.0e-21	96.5	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
638023650	336	42.32	1	336	1	326	2.0e-68	252	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
638023651	332	36.14	1	325	5	320	2.0e-75	276	COG0042	tRNA-dihydrouridine synthase	323
638023653	509	41.46	7	478	2	469	1.0e-113	403	COG0427	Acyl-CoA hydrolase	501
638023654	737	43.8	46	725	3	683	0.0e+00	784	COG0339	Zn-dependent oligopeptidase	683
638023655	272	55.3	9	271	2	263	3.0e-86	311	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
638023656	546	21.94	136	521	9	422	1.0e-29	124	COG3325	Chitinase, GH18 family	441
638023657	488	22.99	46	488	13	408	6.0e-43	169	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
638023659	507	24.89	114	336	60	249	5.0e-07	49.6	COG3063	Tfp pilus assembly protein PilF	250
638023666	466	48.57	15	466	14	435	0.0e+00	530	COG0017	Aspartyl/asparaginyl-tRNA synthetase	435
638023671	458	31.13	10	457	2	409	1.0e-59	224	COG2124	Cytochrome P450	411
638023673	239	60.94	1	233	1	233	8.0e-94	336	COG0813	Purine-nucleoside phosphorylase	236
638023676	418	43.06	1	409	27	444	3.0e-102	365	COG0513	Superfamily II DNA and RNA helicase	513
638023677	192	24.82	50	183	3	132	9.0e-11	60.3	COG1569	Predicted nucleic acid-binding protein, contains PIN domain	142
638023681	337	41.16	1	336	1	326	1.0e-64	240	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
638023682	607	33.33	3	213	38	237	7.0e-36	145	COG1718	Serine/threonine-protein kinase RIO1	268
638023685	472	41.81	5	448	4	454	7.0e-126	444	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
638023687	247	30.32	12	229	11	228	4.0e-19	88.4	COG3541	Predicted nucleotidyltransferase	248
638023688	398	22.47	58	382	23	377	5.0e-14	72.3	COG1680	CubicO group peptidase, beta-lactamase class C family	390
638023691	243	32.55	1	241	2	253	1.0e-44	173	COG3228	Mlc titration factor MtfA, regulates ptsG expression	266
638023692	317	59.72	12	294	6	282	5.0e-100	357	COG1072	Panthothenate kinase	283
638023693	463	37.31	5	462	15	470	4.0e-106	378	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638023696	157	45.16	1	153	2	152	3.0e-40	157	COG2153	Predicted N-acyltransferase, GNAT family	155
638023697	357	33.14	20	356	16	351	4.0e-41	162	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
638023698	287	35.04	17	284	2	245	3.0e-47	182	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
638023701	562	43.9	5	550	3	501	0.0e+00	476	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
638023702	608	47.28	23	608	3	587	0.0e+00	574	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
638023703	570	50.45	12	459	1	428	0.0e+00	533	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
638023704	305	35.74	9	305	16	261	3.0e-51	195	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
638023705	266	53.56	6	243	3	241	1.0e-70	260	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
638023706	221	36.06	12	215	4	210	7.0e-37	147	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
638023707	240	40.25	2	237	5	241	4.0e-54	204	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
638023715	284	37.82	5	275	7	278	1.0e-46	180	COG3687	Predicted metal-dependent hydrolase	280
638023716	1302	37.81	165	992	1	741	0.0e+00	728	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
638023716	1302	41.31	1045	1302	1	231	4.0e-68	254	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
638023717	140	55.97	4	136	1	134	4.0e-56	210	COG0229	Peptide methionine sulfoxide reductase MsrB	140
638023720	586	21.51	16	411	20	480	4.0e-11	63.4	COG1297	Uncharacterized membrane protein, oligopeptide transporter (OPT) family	624
638023721	517	19.92	189	432	11	215	1.0e-11	64.8	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
638023724	432	25.71	14	323	4	302	1.0e-23	104	COG3919	Predicted ATP-dependent carboligase, ATP-grasp superfamily	415
638023725	480	30.77	49	449	11	394	2.0e-63	236	COG0019	Diaminopimelate decarboxylase	394
638023726	292	20.2	11	292	1	287	2.0e-15	76.7	COG1216	Glycosyltransferase, GT2 family	305
638023727	249	34.31	12	245	17	253	3.0e-43	168	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
638023729	385	28.01	15	385	2	377	2.0e-34	140	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638023730	562	32.25	23	533	3	472	2.0e-98	353	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
638023731	469	29.61	3	343	30	384	4.0e-48	185	COG1680	CubicO group peptidase, beta-lactamase class C family	390
638023734	164	16.77	3	156	10	163	6.0e-08	50.4	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638023736	277	38.08	4	258	5	261	8.0e-52	197	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
638023737	186	20.73	2	164	8	168	1.0e-07	50	COG2203	GAF domain	175
638023738	166	29.7	2	166	3	167	1.0e-26	113	COG3663	G:T/U-mismatch repair DNA glycosylase	169
638023739	315	38.19	4	312	2	309	3.0e-76	279	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
638023740	467	24.94	57	463	27	406	5.0e-33	135	COG1228	Imidazolonepropionase or related amidohydrolase	406
638023741	205	48.15	43	203	4	163	4.0e-44	171	COG4297	Uncharacterized protein YjlB	163
638023742	429	30.2	49	429	30	404	4.0e-48	185	COG1228	Imidazolonepropionase or related amidohydrolase	406
638023744	124	54.03	1	124	1	123	2.0e-22	97.6	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
638023749	450	48.36	24	450	11	435	0.0e+00	477	COG1362	Aspartyl aminopeptidase	437
638023750	677	47.67	13	658	63	715	0.0e+00	661	COG2943	Membrane glycosyltransferase	736
638023752	529	46.92	18	529	12	528	0.0e+00	578	COG3131	Periplasmic glucans biosynthesis protein	534
638023755	1767	41.38	1	914	3	930	0.0e+00	889	COG0178	Excinuclease UvrABC ATPase subunit	935
638023756	196	50	40	195	3	162	1.0e-56	212	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
638023762	213	36.02	26	211	1	180	5.0e-22	97.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638023764	387	32.47	2	381	12	376	1.0e-39	157	COG1944	Ribosomal protein S12 methylthiotransferase accessory factor YcaO	398
638023765	387	43.58	9	226	4	219	4.0e-46	178	COG3482	Uncharacterized protein	237
638023766	687	20.05	24	399	2	383	3.0e-24	107	COG0515	Serine/threonine protein kinase	384
638023768	260	25.19	13	260	20	278	8.0e-13	67.7	COG0863	DNA modification methylase	302
638023770	425	36.93	1	416	6	405	4.0e-76	278	COG1301	Na+/H+-dicarboxylate symporter	415
638023771	161	46.3	1	161	1	162	7.0e-42	163	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
638023772	631	22.86	45	627	11	617	5.0e-41	162	COG1297	Uncharacterized membrane protein, oligopeptide transporter (OPT) family	624
638023774	642	42.83	1	535	1	529	0.0e+00	503	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
638023775	704	51.07	1	695	1	694	0.0e+00	831	COG0480	Translation elongation factor EF-G, a GTPase	697
638023778	467	36.92	1	455	2	453	4.0e-113	401	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
638023782	268	38.93	26	260	5	244	7.0e-52	197	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
638023783	240	39.66	1	236	1	235	8.0e-47	180	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
638023784	1913	25.65	372	1907	135	1621	0.0e+00	536	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
638023786	796	38.47	11	792	1	731	0.0e+00	549	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
638023791	274	34.19	34	265	12	243	1.0e-49	190	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
638023795	433	19.95	5	429	7	405	2.0e-31	130	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
638023797	247	47.56	10	233	1	224	4.0e-75	274	COG1136	ABC-type lipoprotein export system, ATPase component	226
638023804	278	29.82	6	225	24	247	5.0e-27	115	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
638023806	272	31.93	12	245	11	234	2.0e-30	126	COG4669	Type III secretory pathway, lipoprotein EscJ	246
638023808	223	28.93	45	222	40	234	2.0e-12	66.5	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
638023809	437	58.89	5	436	9	440	0.0e+00	586	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
638023812	467	21.54	33	345	16	319	1.0e-18	88.4	COG1868	Flagellar motor switch protein FliM	332
638023812	467	32	363	462	34	133	2.0e-14	74.3	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
638023813	287	21.43	157	281	14	136	6.0e-08	51.8	COG3190	Flagellar biogenesis protein FliO	137
638023814	231	44.75	13	231	2	213	9.0e-53	200	COG4790	Type III secretory pathway, component EscR	214
638023815	87	56.79	7	87	9	89	4.0e-17	79.4	COG1987	Flagellar biosynthesis protein FliQ	89
638023816	272	30.59	18	272	10	258	2.0e-26	112	COG1684	Flagellar biosynthesis protein FliR	258
638023817	359	40.96	1	353	2	355	5.0e-93	334	COG1377	Flagellar biosynthesis protein FlhB	363
638023830	707	48.41	12	704	11	686	0.0e+00	700	COG4789	Type III secretory pathway, component EscV	689
638023831	356	30.77	72	225	4	157	6.0e-12	65.4	COG1716	Forkhead associated (FHA) domain, binds pSer, pThr, pTyr	191
638023834	268	31.74	14	178	2	166	7.0e-12	64.8	COG1714	Uncharacterized membrane protein YckC, RDD family	172
638023837	513	25.54	104	486	71	485	3.0e-47	183	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
638023839	338	32.51	95	297	2	202	3.0e-27	116	COG1300	Uncharacterized membrane protein SpoIIM, required for sporulation	207
638023841	427	32.78	1	423	7	416	2.0e-52	200	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
638023842	332	48.43	22	332	13	329	1.0e-67	250	COG0714	MoxR-like ATPase	329
638023846	566	52.51	195	566	43	418	8.0e-126	444	COG1158	Transcription termination factor Rho	422
638023847	832	39.71	521	792	45	306	9.0e-53	202	COG0616	Periplasmic serine protease, ClpP class	317
638023850	643	49.38	3	643	1	635	0.0e+00	799	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
638023851	813	45.37	51	787	4	730	0.0e+00	737	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
638023856	218	24.79	1	217	9	246	1.0e-23	103	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
638023860	288	32.17	32	145	8	121	2.0e-13	69.6	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
638023866	167	37.13	5	164	13	179	3.0e-25	108	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638023867	546	48.59	195	543	107	460	1.0e-106	380	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638023870	533	20.68	4	341	12	352	4.0e-21	96.5	COG4972	Tfp pilus assembly protein, ATPase PilM	354
638023876	141	29.25	9	132	2	148	4.0e-10	57.4	COG2165	Type II secretory pathway, pseudopilin PulG	149
638023878	418	40.77	1	417	1	396	8.0e-100	357	COG1459	Type II secretory pathway, component PulF	397
638023879	605	49.9	99	603	5	500	0.0e+00	548	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
638023880	863	25.3	68	733	36	572	8.0e-66	245	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
638023881	314	19.59	22	306	19	268	2.0e-15	77	COG3031	Type II secretory pathway, component PulC	275
638023882	468	49.78	1	449	2	453	0.0e+00	493	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638023884	448	36.84	4	448	2	454	7.0e-87	314	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
638023885	493	42.3	34	490	4	454	1.0e-111	397	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
638023886	704	28.03	49	194	1	157	2.0e-10	61.9	COG1716	Forkhead associated (FHA) domain, binds pSer, pThr, pTyr	191
638023890	323	29.97	1	309	5	316	6.0e-39	155	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
638023895	135	46.85	16	126	11	120	4.0e-26	110	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
638023896	415	37.66	45	280	20	256	5.0e-44	172	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
638023898	337	33.13	1	327	1	326	9.0e-50	190	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
638023899	158	38.71	2	156	1	155	7.0e-34	136	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
638023900	380	45.33	11	373	3	363	1.0e-108	386	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
638023901	165	65.16	6	160	2	154	3.0e-55	207	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
638023902	604	38.35	8	597	17	611	0.0e+00	500	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
638023903	476	19.3	58	454	1	393	2.0e-20	93.8	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
638023908	427	25.2	35	410	43	383	2.0e-17	83.7	COG2814	Predicted arabinose efflux permease, MFS family	394
638023909	345	43.36	9	345	2	333	2.0e-85	309	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
638023911	548	33.1	113	528	2	412	7.0e-66	245	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
638023912	406	51.91	6	339	1	341	8.0e-88	317	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
638023913	137	47.45	1	136	1	137	1.0e-42	165	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
638023914	316	37.97	8	296	3	289	2.0e-61	229	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
638023916	710	31.63	5	278	1	279	4.0e-41	163	COG0515	Serine/threonine protein kinase	384
638023919	325	30.43	1	320	5	309	3.0e-36	145	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
638023920	320	29.07	7	262	3	245	7.0e-20	91.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638023921	263	51.09	18	246	15	243	2.0e-79	289	COG0020	Undecaprenyl pyrophosphate synthase	245
638023922	276	32.71	7	270	1	263	1.0e-32	133	COG0575	CDP-diglyceride synthetase	265
638023925	255	29.69	11	237	2	219	9.0e-25	107	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
638023926	344	33.82	5	340	2	334	8.0e-57	214	COG0136	Aspartate-semialdehyde dehydrogenase	334
638023930	226	34.52	8	87	1	84	1.0e-09	56.9	COG1977	Molybdopterin converting factor, small subunit	84
638023930	226	53.19	87	226	1	141	3.0e-42	165	COG0314	Molybdopterin synthase catalytic subunit	149
638023932	411	21.52	6	396	4	391	3.0e-13	69.8	COG2814	Predicted arabinose efflux permease, MFS family	394
638023933	530	31.1	1	340	3	374	2.0e-34	140	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
638023934	140	40.58	4	133	6	142	1.0e-26	112	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
638023936	658	47.42	84	643	1	528	0.0e+00	676	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
638023937	451	33.95	39	417	12	382	2.0e-72	266	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
638023938	209	38.65	1	205	1	206	1.0e-36	146	COG0406	Broad specificity phosphatase PhoE	208
638023940	293	58.33	82	269	1	191	5.0e-60	224	COG0164	Ribonuclease HII	199
638023943	591	39.59	5	581	1	551	7.0e-124	438	COG3975	Predicted metalloprotease, contains C-terminal PDZ domain	558
638023944	472	38.75	157	472	39	355	7.0e-69	254	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
638023948	566	38.43	1	216	4	208	1.0e-36	148	COG0125	Thymidylate kinase	208
638023952	762	29.39	8	283	1	281	4.0e-35	143	COG0515	Serine/threonine protein kinase	384
638023953	110	35.71	1	110	1	110	3.0e-12	63.8	COG0607	Rhodanese-related sulfurtransferase	110
638023954	399	40.57	27	130	3	108	8.0e-18	85	COG0607	Rhodanese-related sulfurtransferase	110
638023954	399	57.14	134	380	3	254	3.0e-75	275	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
638023955	108	52.78	1	108	3	110	4.0e-30	122	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
638023956	172	42.58	1	155	1	155	2.0e-40	158	COG1607	Acyl-CoA hydrolase	157
638023957	213	31.58	10	173	5	173	4.0e-29	121	COG1428	Deoxyadenosine/deoxycytidine kinase	216
638023958	273	31.6	12	269	3	257	1.0e-33	136	COG0584	Glycerophosphoryl diester phosphodiesterase	257
638023962	841	23.04	33	408	1	377	7.0e-34	139	COG0515	Serine/threonine protein kinase	384
638023969	310	53.21	1	310	17	324	5.0e-120	424	COG0379	Quinolinate synthase	324
638023972	970	40.94	289	540	83	329	9.0e-44	172	COG0642	Signal transduction histidine kinase	336
638023973	462	40.96	13	443	18	498	5.0e-107	381	COG3104	Dipeptide/tripeptide permease	498
638023974	484	26	11	451	18	487	2.0e-58	220	COG3104	Dipeptide/tripeptide permease	498
638023975	966	60.38	5	944	4	935	0.0e+00	1424	COG0178	Excinuclease UvrABC ATPase subunit	935
638023977	185	39.52	9	173	2	168	5.0e-44	170	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
638023978	530	34.6	209	490	1	276	2.0e-40	160	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
638023978	530	39.34	4	186	6	179	9.0e-42	165	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
638023981	273	25.5	5	142	18	163	3.0e-09	56.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
638023982	1079	16.76	79	1070	107	1078	2.0e-30	128	COG3857	ATP-dependent helicase/DNAse subunit B	1108
638023983	1220	23.92	4	1115	9	1081	2.0e-84	307	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
638023984	436	59.31	1	435	1	430	0.0e+00	617	COG0104	Adenylosuccinate synthase	430
638023988	256	27.13	5	191	19	195	2.0e-15	76.7	COG3361	Uncharacterized protein YqjF, DUF2071 family	240
638023992	822	35	540	797	39	285	1.0e-52	201	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
638023993	164	38.99	2	160	2	159	8.0e-38	149	COG1329	RNA polymerase-interacting regulator, CarD/CdnL/TRCF family	166
638023996	504	52.49	21	498	2	462	0.0e+00	604	COG0215	Cysteinyl-tRNA synthetase	464
638023997	575	23.54	148	562	13	431	3.0e-35	143	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
638023998	704	64.11	1	666	2	663	0.0e+00	1062	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
638023999	646	43.93	1	609	1	581	0.0e+00	559	COG0322	Excinuclease UvrABC, nuclease subunit	581
638024007	227	51.54	4	224	2	228	5.0e-73	267	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
638024008	196	56.15	8	191	5	191	8.0e-59	220	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
638024009	364	26.59	15	182	1	173	8.0e-13	68.1	COG2203	GAF domain	175
638024009	364	38.8	166	347	2	181	2.0e-34	139	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638024011	286	26.79	10	271	7	271	1.0e-37	150	COG1792	Cell shape-determining protein MreC	284
638024013	679	30.77	9	627	7	594	5.0e-101	362	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
638024014	375	37.2	5	375	14	375	4.0e-74	272	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
638024017	242	43.28	2	236	22	259	6.0e-73	267	COG2326	Polyphosphate kinase 2, PPK2 family	270
638024020	271	25.49	4	258	4	255	6.0e-21	94.9	COG4137	ABC-type uncharacterized transport system, permease component	265
638024021	441	43.1	1	418	1	414	6.0e-101	361	COG0373	Glutamyl-tRNA reductase	414
638024022	314	54.64	2	302	1	302	2.0e-103	369	COG0181	Porphobilinogen deaminase	307
638024023	256	39.84	7	253	1	247	5.0e-38	151	COG1587	Uroporphyrinogen-III synthase	248
638024024	615	45.86	119	613	13	498	0.0e+00	496	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
638024027	794	21.43	1	653	1	498	6.0e-51	196	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
638024029	487	24.16	39	462	23	439	6.0e-29	122	COG2271	Sugar phosphate permease	448
638024032	389	50.29	8	352	11	357	4.0e-113	401	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
638024033	328	56.04	3	324	1	323	0.0e+00	462	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
638024034	527	46.31	127	526	5	402	2.0e-95	343	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
638024041	479	39.34	1	476	6	470	6.0e-125	441	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
638024045	259	33.81	24	233	8	202	1.0e-29	123	COG0560	Phosphoserine phosphatase	212
638024046	685	34.28	29	297	2	275	3.0e-48	187	COG0515	Serine/threonine protein kinase	384
638024047	188	27.34	61	186	32	156	2.0e-10	59.2	COG0835	Chemotaxis signal transduction protein	165
638024048	485	34.47	8	262	1	264	4.0e-52	199	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
638024049	538	29.08	147	538	20	408	3.0e-41	163	COG0840	Methyl-accepting chemotaxis protein	408
638024051	194	28.1	41	183	1	151	4.0e-17	81.5	COG0835	Chemotaxis signal transduction protein	165
638024052	848	31.21	1	719	1	715	7.0e-106	378	COG0643	Chemotaxis protein histidine kinase CheA	716
638024053	290	17.06	36	273	54	297	8.0e-06	44.8	COG0642	Signal transduction histidine kinase	336
638024055	439	51.25	6	439	1	436	0.0e+00	559	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
638024056	591	26.71	105	543	19	437	2.0e-39	157	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
638024060	372	26.29	13	183	11	173	8.0e-13	68.4	COG2229	Signal recognition particle receptor subunit beta, a GTPase	187
638024061	63	45.61	1	55	1	57	1.0e-10	58	COG0227	Ribosomal protein L28	77
638024062	526	19.43	35	514	3	479	1.0e-11	65.1	COG1233	Phytoene dehydrogenase-related protein	487
638024063	229	34.6	7	216	1	210	3.0e-38	152	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
638024064	360	34.8	1	202	3	198	7.0e-37	148	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638024065	145	50	1	145	5	150	9.0e-37	145	COG1683	Uncharacterized conserved protein YbbK, DUF523 family	156
638024066	224	53.27	6	204	1	199	8.0e-73	266	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
638024067	345	60.64	1	343	2	343	0.0e+00	477	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
638024068	216	27.81	13	196	26	212	1.0e-24	106	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
638024070	283	60.99	1	282	1	281	2.0e-112	398	COG0777	Acetyl-CoA carboxylase beta subunit	294
638024071	410	46.02	2	401	28	423	1.0e-109	390	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
638024077	233	21.95	7	211	2	201	7.0e-12	64.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638024078	260	41.8	1	254	2	255	2.0e-47	182	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638024079	329	31.43	97	297	43	252	9.0e-27	114	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
638024081	254	40.41	3	232	10	251	1.0e-38	153	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
638024089	843	33.17	561	762	28	216	3.0e-22	101	COG2114	Adenylate cyclase, class 3	227
638024092	254	30.12	22	187	15	147	2.0e-25	109	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
638024093	482	40.65	48	415	19	332	5.0e-72	265	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
638024095	415	52.58	27	414	10	397	0.0e+00	470	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
638024097	634	23.7	121	504	5	402	9.0e-24	105	COG3119	Arylsulfatase A or related enzyme	475
638024099	187	57.14	17	162	18	163	1.0e-52	199	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
638024100	123	50.85	6	123	5	122	2.0e-27	114	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
638024101	523	28.07	154	520	46	408	5.0e-36	145	COG0840	Methyl-accepting chemotaxis protein	408
638024103	296	21.26	93	266	19	180	4.0e-07	48.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638024104	1038	29.39	67	342	2	277	1.0e-36	149	COG0515	Serine/threonine protein kinase	384
638024105	272	39.29	1	250	3	254	5.0e-40	157	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
638024106	144	24.35	25	136	15	129	1.0e-09	56.2	COG1765	Uncharacterized OsmC-related protein	137
638024108	696	50.46	6	658	3	652	0.0e+00	834	COG1166	Arginine decarboxylase (spermidine biosynthesis)	652
638024109	399	43.8	52	388	47	390	1.0e-98	353	COG1219	ATP-dependent protease Clp, ATPase subunit	408
638024113	535	47.27	6	516	7	494	0.0e+00	473	COG0443	Molecular chaperone DnaK (HSP70)	579
638024114	277	20.14	1	266	1	242	1.0e-06	47.3	COG0121	Predicted glutamine amidotransferase	252
638024115	153	30.07	15	145	7	144	6.0e-11	60.4	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
638024116	154	30.25	30	140	8	125	4.0e-09	54.6	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
638024119	109	47.37	1	95	2	96	2.0e-24	104	COG5470	Uncharacterized conserved protein, DUF1330 family	96
638024123	480	43.48	1	229	98	326	2.0e-54	207	COG1796	DNA polymerase/3'-5' exonuclease PolX	326
638024124	105	32.04	1	100	3	104	6.0e-11	59.2	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
638024125	155	52	7	154	12	161	1.0e-43	168	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
638024139	711	55.07	203	703	1	481	2.0e-128	453	COG0464	AAA+-type ATPase, SpoVK/Ycf46/Vps4 family	494
638024144	238	46.46	14	234	3	226	9.0e-55	206	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638024146	310	22.89	66	292	14	258	5.0e-08	52.1	COG0031	Cysteine synthase	300
638024149	800	16.71	412	798	2	417	8.0e-18	86.3	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
638024151	1077	27.56	544	917	103	447	3.0e-45	177	COG5002	Signal transduction histidine kinase	459
638024152	354	53.37	1	354	10	362	2.0e-120	426	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
638024153	437	68.54	12	436	3	427	0.0e+00	595	COG3508	Homogentisate 1,2-dioxygenase	427
638024154	126	31.13	20	125	6	103	1.0e-15	75.4	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
638024155	470	31.94	19	449	19	447	2.0e-62	233	COG0534	Na+-driven multidrug efflux pump	455
638024161	749	36.51	1	745	106	931	0.0e+00	714	COG0178	Excinuclease UvrABC ATPase subunit	935
638024162	1555	27.43	821	1152	18	334	2.0e-28	122	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
638024162	1555	30.42	13	305	7	307	1.0e-31	133	COG0223	Methionyl-tRNA formyltransferase	307
638024164	2088	29.24	1146	1372	7	239	3.0e-15	79.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638024164	2088	42.62	9	911	1	894	0.0e+00	741	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638024166	344	31.78	6	325	4	308	6.0e-36	145	COG0470	DNA polymerase III, delta prime subunit	324
638024169	266	34.57	1	232	1	233	2.0e-30	125	COG3332	Uncharacterized conserved protein, contains NRDE domain	270
638024170	703	39.18	1	554	3	558	0.0e+00	561	COG0143	Methionyl-tRNA synthetase	558
638024170	703	48.25	597	702	10	123	1.0e-21	98.9	COG0073	tRNA-binding EMAP/Myf domain	123
638024172	258	46.72	1	255	1	256	1.0e-76	279	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
638024174	466	25.15	17	349	1	287	2.0e-22	100	COG3481	3'-5' exoribonuclease YhaM, can participate in 23S rRNA maturation,  HD superfamily	287
638024175	385	32.23	11	384	2	392	6.0e-60	224	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
638024177	531	33.33	6	530	1	483	8.0e-94	338	COG2509	Uncharacterized FAD-dependent dehydrogenase	486
638024179	217	30.56	19	126	11	118	1.0e-17	83.7	COG0818	Diacylglycerol kinase	123
638024181	336	61.93	2	331	1	330	0.0e+00	467	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
638024182	395	58.9	1	395	3	393	0.0e+00	518	COG0126	3-phosphoglycerate kinase	395
638024183	256	56.4	6	255	2	247	2.0e-83	302	COG0149	Triosephosphate isomerase	251
638024184	132	37.18	1	78	1	77	2.0e-12	64.8	COG1314	Preprotein translocase subunit SecG	86
638024196	344	25.88	34	334	14	319	2.0e-20	93.7	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
638024197	260	42.08	2	258	5	258	9.0e-42	163	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
638024198	272	48.41	20	271	1	246	9.0e-73	267	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
638024199	209	25.83	87	204	5	124	4.0e-13	68	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
638024200	123	40.86	9	99	16	108	4.0e-10	57.1	COG0640	DNA-binding transcriptional regulator, ArsR family	110
638024201	158	22.64	2	154	4	144	3.0e-11	61.2	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
638024205	473	24.42	20	299	2	288	3.0e-30	126	COG0515	Serine/threonine protein kinase	384
638024206	514	27.85	32	487	1	456	3.0e-60	226	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638024207	294	34.67	1	294	1	296	1.0e-27	117	COG0583	DNA-binding transcriptional regulator, LysR family	297
638024208	545	40.22	1	531	2	535	0.0e+00	479	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
638024209	477	40.42	6	475	1	468	4.0e-107	382	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638024210	208	38.89	6	202	4	200	2.0e-47	182	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
638024211	444	47.54	18	443	12	436	0.0e+00	487	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
638024216	464	24.22	344	464	5	129	4.0e-06	46.6	COG4935	Regulatory P domain of the subtilisin-like proprotein convertases and other proteases	177
638024217	484	35.6	4	474	2	475	1.0e-96	347	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
638024218	733	39.21	20	725	1	709	0.0e+00	634	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
638024222	1107	28.99	172	1081	92	962	0.0e+00	514	COG4403	Lantibiotic modifying enzyme	963
638024225	606	41.21	17	590	18	586	0.0e+00	509	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
638024226	419	35.08	35	406	1	347	2.0e-69	256	COG3191	L-aminopeptidase/D-esterase	348
638024234	199	23.08	1	169	6	174	1.0e-05	43.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638024236	195	22.04	14	191	6	191	1.0e-06	46.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638024237	604	24.95	57	536	1	433	6.0e-54	206	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
638024240	397	34.45	24	346	20	347	8.0e-40	158	COG0628	Predicted PurR-regulated permease PerM	355
638024243	187	27.59	33	176	2	138	1.0e-19	89.9	COG2193	Bacterioferritin (cytochrome b1)	157
638024244	535	31.09	13	530	6	502	3.0e-87	316	COG1070	Sugar (pentulose or hexulose) kinase	502
638024245	509	30.8	47	464	15	436	2.0e-65	244	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
638024246	392	38.56	10	392	2	377	1.0e-81	297	COG1454	Alcohol dehydrogenase, class IV	377
638024247	105	23.33	6	95	4	93	5.0e-13	66.1	COG1359	Quinol monooxygenase YgiN	100
638024249	804	19.38	94	700	1	665	2.0e-13	72	COG3899	Predicted ATPase	849
638024250	381	21.46	150	378	13	200	2.0e-06	47.2	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
638024251	227	28.07	1	222	2	229	7.0e-28	117	COG1011	FMN phosphatase YigB, HAD superfamily	229
638024253	438	28.02	18	412	10	398	1.0e-62	234	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
638024256	449	34.85	1	64	2	67	5.0e-10	59.6	COG3831	WGR domain, predicted DNA-binding domain in MolR	85
638024257	451	32.93	9	90	12	85	3.0e-14	73.4	COG3831	WGR domain, predicted DNA-binding domain in MolR	85
638024260	340	22.8	22	339	11	315	1.0e-21	97.9	COG0714	MoxR-like ATPase	329
638024263	706	30.72	249	693	150	588	4.0e-59	223	COG0465	ATP-dependent Zn proteases	596
638024266	202	29.17	11	163	1	167	8.0e-17	80.4	COG0602	Organic radical activating enzyme	212
638024271	823	23.15	4	812	1	761	3.0e-57	217	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
638024275	779	24.94	9	382	2	376	2.0e-39	158	COG0515	Serine/threonine protein kinase	384
638024276	791	23.87	11	366	1	363	9.0e-40	159	COG0515	Serine/threonine protein kinase	384
638024279	514	56.73	1	514	3	515	0.0e+00	696	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
638024281	421	55.82	4	415	2	421	0.0e+00	490	COG0151	Phosphoribosylamine-glycine ligase	428
638024282	370	25.75	1	365	1	363	1.0e-32	134	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
638024283	371	22.65	4	360	3	364	4.0e-31	129	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
638024285	387	27.27	19	374	2	379	1.0e-27	117	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638024286	381	23.2	1	369	1	380	9.0e-23	101	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638024287	464	45.18	238	464	1	226	4.0e-68	252	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
638024290	930	26.37	56	714	83	689	8.0e-98	352	COG0209	Ribonucleotide reductase alpha subunit	696
638024291	113	49.12	48	104	1	57	5.0e-13	66.5	COG3411	(2Fe-2S) ferredoxin	64
638024292	599	38.95	188	598	13	436	3.0e-88	319	COG3325	Chitinase, GH18 family	441
638024294	228	30.94	47	224	2	182	1.0e-20	93.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638024302	367	41.02	4	293	24	307	1.0e-61	230	COG3397	Predicted carbohydrate-binding protein, contains CBM5 and CBM33 domains	308
638024311	183	19.9	10	163	5	200	9.0e-09	53.7	COG1335	Nicotinamidase-related amidase	205
638024312	290	26.97	16	282	9	269	8.0e-25	107	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
638024313	270	30.74	21	269	2	254	4.0e-49	188	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
638024315	309	26.05	1	306	6	303	1.0e-36	147	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
638024318	113	38.83	6	105	2	104	2.0e-14	70.8	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
638024319	185	35.14	1	184	15	195	3.0e-42	164	COG0302	GTP cyclohydrolase I	195
638024320	472	43.48	19	467	1	457	9.0e-88	317	COG0277	FAD/FMN-containing dehydrogenase	459
638024322	620	38.28	18	619	17	613	0.0e+00	539	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
638024327	392	45.48	1	390	1	390	1.0e-96	346	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
638024329	199	38.74	74	184	16	126	6.0e-15	74.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
638024330	1046	37.06	1	1006	2	1009	0.0e+00	854	COG0841	Multidrug efflux pump subunit AcrB	1009
638024331	373	28.38	7	371	1	367	8.0e-18	85.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
638024332	379	39.06	1	375	1	384	1.0e-86	314	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638024333	431	51.59	2	405	1	400	2.0e-100	359	COG1301	Na+/H+-dicarboxylate symporter	415
638024336	213	46.15	15	208	13	205	8.0e-49	186	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
638024337	2008	18.77	398	2004	216	1618	3.0e-66	248	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
638024339	420	38.07	13	419	5	400	1.0e-96	347	COG0162	Tyrosyl-tRNA synthetase	401
638024340	262	51.35	1	257	1	257	1.0e-83	303	COG1692	Calcineurin-like phosphoesterase	266
638024341	212	34.22	18	201	5	189	5.0e-35	140	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
638024343	332	27.03	16	327	1	318	3.0e-37	149	COG0515	Serine/threonine protein kinase	384
638024346	381	45.95	1	381	2	383	3.0e-117	415	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
638024347	343	30.95	3	327	2	332	3.0e-42	166	COG0618	nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs	332
638024350	315	39.59	11	303	1	282	6.0e-68	251	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
638024352	312	30.4	26	287	25	261	9.0e-31	127	COG0714	MoxR-like ATPase	329
638024354	1395	20.02	241	1081	178	1009	3.0e-23	105	COG1196	Chromosome segregation ATPase	1163
638024355	1030	26.29	6	351	41	381	2.0e-29	125	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638024356	784	28.1	202	345	15	166	3.0e-06	47.7	COG3330	Uncharacterized conserved protein	215
638024357	529	48.39	4	528	3	503	0.0e+00	524	COG1543	Predicted glycosyl hydrolase, contains GH57 and DUF1957 domains	504
638024358	493	43.68	25	383	2	345	1.0e-64	241	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
638024359	197	25.6	4	196	10	213	4.0e-16	78.4	COG2755	Lysophospholipase L1 or related esterase	216
638024360	645	48.24	436	604	11	177	2.0e-40	161	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638024362	243	43.57	3	240	14	246	2.0e-56	212	COG1496	Copper oxidase (laccase) domain	249
638024365	1242	36.14	19	302	4	282	9.0e-49	189	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
638024365	1242	37.31	1096	1224	3	136	1.0e-27	119	COG0551	ssDNA-binding Zn-finger and Zn-ribbon domains of topoisomerase 1	140
638024365	1242	48.84	465	1058	2	569	0.0e+00	652	COG0550	DNA topoisomerase IA	570
638024366	260	25.38	50	245	19	212	7.0e-16	77.7	COG0811	Biopolymer transport protein ExbB/TolQ	216
638024367	173	20.65	1	155	1	122	1.0e-07	49.8	COG0848	Biopolymer transport protein ExbD	137
638024369	130	27.43	9	121	6	116	1.0e-09	55.4	COG1734	RNA polymerase-binding transcription factor DksA	120
638024370	457	55.71	5	438	3	435	0.0e+00	561	COG1206	Folate-dependent tRNA-U54 methylase TrmFO/GidA	439
638024373	300	48.01	1	300	2	300	1.0e-85	310	COG4974	Site-specific recombinase XerD	300
638024375	175	65.14	1	175	1	175	3.0e-70	257	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
638024376	459	61.87	1	459	1	444	0.0e+00	619	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
638024377	414	54.23	15	413	2	398	0.0e+00	523	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
638024379	613	48.75	1	557	1	533	0.0e+00	514	COG0443	Molecular chaperone DnaK (HSP70)	579
638024381	159	22.01	1	158	15	155	3.0e-07	48.2	COG2030	Acyl dehydratase	159
638024382	131	26.28	2	130	23	155	7.0e-12	62.8	COG2030	Acyl dehydratase	159
638024383	380	25.13	12	352	2	373	2.0e-27	116	COG3320	Thioester reductase domain of alpha aminoadipate reductase Lys2 and NRPSs	382
638024384	198	43.94	1	197	2	196	2.0e-47	182	COG0237	Dephospho-CoA kinase	201
638024387	206	40.49	1	202	1	198	9.0e-54	203	COG0218	GTP-binding protein EngB required for normal cell division	200
638024389	426	18.87	14	371	23	387	4.0e-08	52.8	COG3307	O-antigen ligase	424
638024390	377	28.5	6	374	3	380	9.0e-34	138	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638024391	363	44.16	50	358	2	310	8.0e-84	304	COG0167	Dihydroorotate dehydrogenase	310
638024392	331	28.27	7	331	15	327	4.0e-43	168	COG1816	Adenosine deaminase	345
638024393	211	37.5	31	211	2	180	1.0e-28	119	COG2840	DNA-nicking endonuclease, Smr domain	184
638024395	288	59.86	4	281	1	279	1.0e-106	379	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
638024396	269	27.7	16	205	20	229	2.0e-24	106	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
638024397	316	29.75	1	312	1	310	1.0e-40	160	COG1397	ADP-ribosylglycohydrolase	314
638024402	290	42.61	11	289	14	290	2.0e-69	255	COG0685	5,10-methylenetetrahydrofolate reductase	291
638024403	362	47.57	1	360	2	371	7.0e-110	390	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
638024404	129	52.71	1	127	1	129	1.0e-39	155	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
638024405	971	56.15	6	443	2	445	0.0e+00	601	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
638024405	971	62.66	475	934	29	496	0.0e+00	726	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
638024406	305	36.81	13	297	4	290	6.0e-63	234	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
638024411	383	45.57	8	383	5	388	7.0e-90	324	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638024413	362	36.48	4	356	2	334	2.0e-70	260	COG0136	Aspartate-semialdehyde dehydrogenase	334
638024414	111	40.91	4	65	5	68	1.0e-08	51.3	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
638024417	158	28.87	21	158	17	152	1.0e-11	62.6	COG2153	Predicted N-acyltransferase, GNAT family	155
638024418	854	32.4	5	853	48	844	0.0e+00	523	COG1643	HrpA-like RNA helicase	845
638024420	234	24.09	4	222	2	211	2.0e-19	89.8	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
638024422	130	22.31	13	127	13	133	6.0e-06	43.3	COG2210	Peroxiredoxin family protein	137
638024424	333	28.71	1	290	1	316	1.0e-35	143	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
638024426	282	42.59	16	277	3	258	1.0e-59	223	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
638024431	396	81.31	1	396	1	394	0.0e+00	703	COG0050	Translation elongation factor EF-Tu, a GTPase	394
638024432	54	60	4	53	1	50	4.0e-09	52.9	COG0267	Ribosomal protein L33	50
638024435	180	49.72	1	177	1	176	2.0e-49	188	COG0250	Transcription antitermination factor NusG	178
638024436	148	61.22	2	148	2	140	3.0e-44	170	COG0080	Ribosomal protein L11	141
638024437	237	58.26	1	229	1	227	1.0e-73	269	COG0081	Ribosomal protein L1	228
638024438	173	38.37	1	172	3	174	5.0e-33	134	COG0244	Ribosomal protein L10	175
638024439	122	60.98	1	122	2	124	1.0e-25	108	COG0222	Ribosomal protein L7/L12	124
638024441	1403	49.88	20	844	7	808	0.0e+00	873	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
638024447	253	25.65	1	226	1	228	4.0e-15	75.4	COG3063	Tfp pilus assembly protein PilF	250
638024449	244	30.83	3	240	5	242	1.0e-32	133	COG1381	Recombinational DNA repair protein (RecF pathway)	251
638024450	340	37.76	14	335	1	311	4.0e-47	181	COG0524	Sugar or nucleoside kinase, ribokinase family	311
638024452	162	26.51	1	162	1	156	2.0e-09	55	COG3708	Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain	157
638024454	606	25.85	35	601	12	612	2.0e-36	147	COG1297	Uncharacterized membrane protein, oligopeptide transporter (OPT) family	624
638024455	1274	32.73	46	302	7	277	4.0e-39	157	COG0515	Serine/threonine protein kinase	384
638024457	457	28.28	22	299	1	290	2.0e-37	150	COG0515	Serine/threonine protein kinase	384
638024458	449	45.45	115	447	116	456	6.0e-92	331	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638024459	122	31.82	5	109	3	111	4.0e-17	80.1	COG3801	Uncharacterized protein	124
638024461	390	32.51	106	387	58	329	5.0e-42	165	COG0642	Signal transduction histidine kinase	336
638024462	772	25.79	23	384	1	365	1.0e-36	148	COG0515	Serine/threonine protein kinase	384
638024463	330	69.39	1	290	5	298	0.0e+00	523	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
638024464	703	43.2	1	696	2	690	0.0e+00	700	COG0751	Glycyl-tRNA synthetase, beta subunit	691
638024469	482	26.39	6	453	10	403	2.0e-45	177	COG4964	Flp pilus assembly protein, secretin CpaC	455
638024470	595	51.56	205	556	6	353	5.0e-114	405	COG4962	Pilus assembly protein, ATPase of CpaF family	355
638024472	908	49	316	908	6	593	0.0e+00	597	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
638024478	330	33.16	93	287	1	196	8.0e-21	94.6	COG1300	Uncharacterized membrane protein SpoIIM, required for sporulation	207
638024479	269	28.4	26	185	5	157	5.0e-11	62.1	COG1714	Uncharacterized membrane protein YckC, RDD family	172
638024480	229	29.9	21	223	14	208	2.0e-28	119	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
638024481	71	39.68	6	68	8	70	6.0e-16	75.5	COG3251	Uncharacterized conserved protein YbdZ, MbtH family	71
638024484	318	33.65	1	317	1	305	5.0e-61	228	COG1893	Ketopantoate reductase	307
638024487	363	41.88	11	351	18	359	1.0e-64	240	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
638024489	125	31.09	1	119	3	117	2.0e-17	81.3	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
638024492	735	33.43	55	719	2	648	3.0e-107	383	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
638024493	494	29.13	30	472	19	448	2.0e-46	180	COG2027	D-alanyl-D-alanine carboxypeptidase	470
638024496	234	21.23	19	224	8	217	6.0e-09	54.5	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
638024501	850	26.38	145	532	16	389	2.0e-24	108	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
638024505	381	25.98	259	381	1	127	4.0e-10	59.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638024506	1273	40.5	3	478	7	482	3.0e-115	410	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
638024506	1273	53.54	479	1266	2	781	0.0e+00	949	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
638024507	278	37.09	3	269	2	274	6.0e-49	187	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
638024510	442	32.46	14	435	2	394	1.0e-57	217	COG2311	Uncharacterized membrane protein YeiB	394
638024511	210	52.17	4	210	3	208	6.0e-75	273	COG0177	Endonuclease III	211
638024514	295	30.27	6	295	3	290	2.0e-37	149	COG0583	DNA-binding transcriptional regulator, LysR family	297
638024515	134	33.82	1	134	3	129	1.0e-13	69.2	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
638024516	728	34.8	1	459	1	449	4.0e-77	282	COG4303	Ethanolamine ammonia-lyase, large subunit	453
638024517	297	54.92	4	297	1	282	7.0e-113	400	COG0447	1,4-Dihydroxy-2-naphthoyl-CoA synthase	282
638024519	256	33.17	49	253	20	223	3.0e-33	135	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
638024523	703	48.55	55	703	6	654	0.0e+00	786	COG3590	Predicted metalloendopeptidase	654
638024525	569	40.52	62	366	3	297	5.0e-85	308	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
638024525	569	43.09	381	568	1	184	7.0e-59	222	COG1838	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain	184
638024532	314	55.37	1	304	1	300	7.0e-87	314	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
638024533	348	62.87	6	346	3	340	0.0e+00	476	COG2130	NADPH-dependent curcumin reductase CurA	340
638024534	356	29.57	34	331	2	280	1.0e-33	137	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
638024535	313	27.57	4	297	2	272	1.0e-27	117	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
638024536	307	21.37	80	307	87	309	4.0e-14	72.7	COG3021	Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily	309
638024540	1242	35.59	20	901	41	843	0.0e+00	641	COG1643	HrpA-like RNA helicase	845
638024545	596	23.74	16	388	1	384	1.0e-30	128	COG0515	Serine/threonine protein kinase	384
638024546	384	24.92	22	334	1	277	2.0e-17	83.3	COG0515	Serine/threonine protein kinase	384
638024549	176	45.1	25	176	1	151	1.0e-31	129	COG0782	Transcription elongation factor, GreA/GreB family	151
638024551	439	49.77	1	439	1	436	0.0e+00	470	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
638024552	101	35.8	17	97	7	86	5.0e-13	66.1	COG2921	Putative lipoic acid-binding regulatory protein	90
638024554	363	22.51	24	356	4	293	1.0e-13	71.1	COG1597	Diacylglycerol kinase family enzyme	301
638024555	636	61.31	1	596	4	577	0.0e+00	669	COG0443	Molecular chaperone DnaK (HSP70)	579
638024557	136	27.87	4	125	1	122	8.0e-10	56	COG3011	Predicted thiol-disulfide oxidoreductase YuxK, DCC family	137
638024558	843	24.21	21	264	21	262	2.0e-12	68.6	COG0714	MoxR-like ATPase	329
638024563	120	45	1	120	1	119	1.0e-19	88.9	COG1734	RNA polymerase-binding transcription factor DksA	120
638024565	547	34.38	17	319	1	311	2.0e-47	184	COG0515	Serine/threonine protein kinase	384
638024567	753	46.31	12	753	3	701	0.0e+00	868	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
638024568	131	48.06	3	130	1	127	2.0e-32	131	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
638024569	551	32.6	371	541	67	244	3.0e-23	103	COG1651	Protein-disulfide isomerase	244
638024570	76	31.94	6	76	7	78	5.0e-11	59.1	COG0425	TusA-related sulfurtransferase	78
638024571	302	32.79	5	302	4	291	4.0e-57	215	COG1131	ABC-type multidrug transport system, ATPase component	293
638024577	553	48.21	6	422	7	416	6.0e-122	431	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638024578	437	21.58	7	251	20	296	4.0e-09	56.5	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638024578	437	24.5	273	419	12	157	1.0e-09	58.1	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
638024580	372	38.71	99	346	44	273	3.0e-56	212	COG2876	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	286
638024581	273	41.54	4	270	1	272	1.0e-75	276	COG0077	Prephenate dehydratase	279
638024582	379	38.04	1	91	4	95	8.0e-15	75	COG1605	Chorismate mutase	101
638024582	379	39.29	99	377	2	278	5.0e-71	261	COG0077	Prephenate dehydratase	279
638024584	142	36.77	3	141	1	155	2.0e-32	131	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
638024586	190	37.43	25	190	36	204	8.0e-27	113	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
638024588	465	22.47	4	420	15	458	3.0e-25	110	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
638024589	231	35.24	13	217	23	229	5.0e-33	134	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
638024590	455	45.75	244	454	18	225	9.0e-62	231	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
638024591	325	43.6	1	319	4	323	1.0e-64	240	COG0391	Archaeal 2-phospho-L-lactate transferase/Bacterial gluconeogenesis factor, CofD/UPF0052 family	323
638024592	358	21.5	5	323	38	352	6.0e-14	71.9	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
638024593	389	23.4	46	380	61	373	1.0e-26	114	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
638024594	397	23.41	10	397	25	401	2.0e-17	83.9	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
638024596	174	34.9	1	149	3	150	7.0e-27	113	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
638024597	303	26.03	2	233	1	236	2.0e-18	87	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
638024599	403	29.32	15	403	10	378	3.0e-23	103	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
638024600	252	22.89	40	230	52	238	4.0e-07	48.8	COG3751	Proline 4-hydroxylase (includes Rps23 Pro-64 3,4-dihydroxylase Tpa1), contains SM-20 domain	252
638024601	155	34.68	33	154	1	124	3.0e-12	65	COG1846	DNA-binding transcriptional regulator, MarR family	126
638024602	245	64.1	1	117	1	117	1.0e-40	159	COG5507	Uncharacterized  conserved protein YbaA, DUF1428 family	117
638024611	297	43.24	9	295	13	307	6.0e-63	234	COG3386	Sugar lactone lactonase YvrE	307
638024613	183	29.13	31	155	2	127	9.0e-16	76.9	COG0526	Thiol-disulfide isomerase or thioredoxin	127
638024614	673	37.29	1	646	1	639	4.0e-118	419	COG1138	Cytochrome c biogenesis factor	648
638024615	158	30.57	1	154	1	152	2.0e-21	95	COG2332	Cytochrome c-type biogenesis protein CcmE	153
638024617	237	29.86	12	217	61	271	1.0e-22	100	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
638024618	233	35.1	12	218	1	207	4.0e-24	105	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
638024619	219	37.67	8	218	3	217	5.0e-45	174	COG1131	ABC-type multidrug transport system, ATPase component	293
638024621	506	16.55	13	424	7	423	5.0e-13	69.4	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
638024622	176	44.3	6	161	33	187	1.0e-31	129	COG1045	Serine acetyltransferase	194
638024623	363	21.87	1	315	1	339	3.0e-15	76.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638024624	394	18.13	70	380	43	371	1.0e-09	58.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638024628	212	35.47	7	202	6	205	1.0e-26	113	COG0352	Thiamine monophosphate synthase	211
638024629	261	61.39	1	259	1	259	2.0e-103	368	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
638024630	88	45.45	23	88	3	68	3.0e-16	76.4	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
638024633	377	29.49	24	324	2	281	3.0e-25	109	COG0515	Serine/threonine protein kinase	384
638024634	354	32.73	33	353	3	312	6.0e-53	201	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
638024638	228	26.22	39	198	12	174	1.0e-08	53.6	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
638024639	265	32.86	1	260	2	282	1.0e-23	104	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638024640	326	36.54	29	326	25	322	2.0e-58	219	COG0598	Mg2+ and Co2+ transporter CorA	322
638024642	277	21.15	25	266	6	261	7.0e-16	77.8	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
638024643	403	45.8	11	401	1	391	1.0e-102	366	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
638024645	210	27.84	15	205	12	205	1.0e-16	79.6	COG2945	Alpha/beta superfamily hydrolase	210
638024646	597	30.93	75	481	66	480	1.0e-24	108	COG1404	Serine protease, subtilisin family	508
638024648	367	20.85	1	207	11	219	3.0e-08	53	COG1266	Membrane protease YdiL, CAAX protease family	226
638024649	851	27.57	123	842	88	791	6.0e-92	332	COG2937	Glycerol-3-phosphate O-acyltransferase	810
638024650	573	35.59	7	573	5	577	0.0e+00	462	COG0018	Arginyl-tRNA synthetase	577
638024653	391	41.56	1	380	2	350	1.0e-98	353	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
638024655	164	35.47	5	162	1	171	6.0e-19	87	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
638024656	123	78.05	1	123	7	129	1.0e-47	181	COG0048	Ribosomal protein S12	129
638024657	156	60.14	2	149	1	148	1.0e-53	202	COG0049	Ribosomal protein S7	148
638024658	691	61.83	1	686	1	681	0.0e+00	940	COG0480	Translation elongation factor EF-G, a GTPase	697
638024659	396	81.06	1	396	1	394	0.0e+00	702	COG0050	Translation elongation factor EF-Tu, a GTPase	394
638024660	102	72.28	1	101	1	101	1.0e-38	151	COG0051	Ribosomal protein S10	104
638024661	207	44.08	1	207	1	211	1.0e-45	176	COG0088	Ribosomal protein L4	214
638024662	97	53.76	3	94	1	93	6.0e-20	89.1	COG0089	Ribosomal protein L23	94
638024663	281	62.82	1	276	1	275	1.0e-104	372	COG0090	Ribosomal protein L2	275
638024664	95	67.03	1	91	1	91	7.0e-35	138	COG0185	Ribosomal protein S19	93
638024665	114	53.51	1	114	9	120	1.0e-26	111	COG0091	Ribosomal protein L22	120
638024666	220	63.18	12	210	1	201	8.0e-76	276	COG0092	Ribosomal protein S3	233
638024667	139	61.76	1	134	2	137	5.0e-46	176	COG0197	Ribosomal protein L16/L10AE	146
638024669	108	48.86	19	106	5	86	2.0e-16	77.6	COG0186	Ribosomal protein S17	87
638024670	122	73.77	1	122	1	122	6.0e-48	182	COG0093	Ribosomal protein L14	122
638024671	111	41.07	1	111	2	104	2.0e-11	61.1	COG0198	Ribosomal protein L24	104
638024672	174	59.2	1	174	6	179	4.0e-67	247	COG0094	Ribosomal protein L5	180
638024673	61	47.54	1	61	1	61	6.0e-13	65.6	COG0199	Ribosomal protein S14	61
638024674	138	52.9	1	138	1	132	2.0e-45	174	COG0096	Ribosomal protein S8	132
638024675	188	47.06	1	186	1	177	9.0e-46	176	COG0097	Ribosomal protein L6P/L9E	178
638024676	148	52.89	31	148	5	125	2.0e-32	131	COG0256	Ribosomal protein L18	125
638024677	173	65.82	7	163	19	176	1.0e-53	202	COG0098	Ribosomal protein S5	181
638024678	89	49.09	3	57	1	55	2.0e-10	57.4	COG1841	Ribosomal protein L30/L7E	55
638024679	175	49.66	4	148	3	151	1.0e-31	129	COG0200	Ribosomal protein L15	152
638024680	448	45.6	1	432	5	430	8.0e-111	394	COG0201	Preprotein translocase subunit SecY	436
638024681	215	40.85	1	213	1	178	1.0e-44	172	COG0563	Adenylate kinase or related kinase	178
638024682	72	72.22	1	72	1	72	1.0e-25	108	COG0361	Translation initiation factor IF-1	75
638024683	38	76.32	1	38	1	38	1.0e-05	41.3	COG0257	Ribosomal protein L36	38
638024684	127	64.46	1	121	1	121	4.0e-43	166	COG0099	Ribosomal protein S13	121
638024685	146	71.09	19	146	2	129	2.0e-45	175	COG0100	Ribosomal protein S11	129
638024686	208	52.38	1	208	1	205	3.0e-54	204	COG0522	Ribosomal protein S4 or related protein	205
638024687	340	52.04	13	331	1	315	7.0e-98	350	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
638024688	139	59.48	1	116	1	116	2.0e-36	144	COG0203	Ribosomal protein L17	116
638024690	459	27.32	230	410	34	214	1.0e-09	58.1	COG3063	Tfp pilus assembly protein PilF	250
638024691	264	35.09	4	227	1	223	3.0e-31	128	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
638024692	204	33.18	1	204	1	210	2.0e-43	169	COG1428	Deoxyadenosine/deoxycytidine kinase	216
638024695	303	26.46	13	302	2	288	7.0e-11	61.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
638024696	303	49.5	3	301	11	308	1.0e-84	306	COG2313	Pseudouridine-5'-phosphate glycosidase (pseudoU degradation)	310
638024697	161	48.65	11	157	10	154	9.0e-42	162	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
638024698	245	42.32	5	241	8	241	2.0e-64	239	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
638024699	536	25.13	6	376	2	382	1.0e-42	168	COG0515	Serine/threonine protein kinase	384
638024700	657	44.22	1	530	1	524	0.0e+00	517	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
638024703	747	34.29	423	694	91	356	1.0e-41	165	COG3852	Signal transduction histidine kinase, nitrogen specific	363
638024704	801	30.13	480	789	2	289	3.0e-24	107	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
638024705	67	65.67	1	67	1	67	5.0e-23	99.1	COG1278	Cold shock protein, CspA family	67
638024706	465	48.18	82	454	18	390	7.0e-85	307	COG1921	Seryl-tRNA(Sec) selenium transferase	395
638024707	192	31.2	44	167	21	143	4.0e-13	68	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
638024708	317	28.82	16	302	3	235	1.0e-30	126	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
638024711	346	49.66	12	301	7	288	1.0e-74	273	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
638024712	436	22.3	133	424	34	319	7.0e-27	115	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
638024715	821	32.08	24	501	2	493	2.0e-75	277	COG1297	Uncharacterized membrane protein, oligopeptide transporter (OPT) family	624
638024719	322	28.38	26	308	4	298	2.0e-18	86.4	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
638024720	326	41.03	9	326	3	329	2.0e-57	216	COG0714	MoxR-like ATPase	329
638024729	224	51.87	1	213	1	213	8.0e-67	246	COG0087	Ribosomal protein L3	218
638024738	615	59.97	4	605	2	603	0.0e+00	870	COG1217	Predicted membrane GTPase involved in stress response	603
638024739	313	28.07	11	291	2	282	3.0e-27	115	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638024741	335	42.62	25	327	2	295	5.0e-76	277	COG1230	Co/Zn/Cd efflux system component	296
638024743	185	44.62	1	183	2	184	4.0e-48	184	COG0742	16S rRNA G966 N2-methylase RsmD	187
638024744	160	62.03	1	157	2	159	6.0e-64	236	COG0669	Phosphopantetheine adenylyltransferase	159
638024745	396	42.57	5	396	1	393	2.0e-106	379	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
638024747	1083	67.51	13	409	1	395	0.0e+00	549	COG0458	Carbamoylphosphate synthase large subunit	400
638024748	361	40.59	1	330	3	341	1.0e-78	287	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
638024749	383	19.22	12	339	7	303	2.0e-09	57	COG3239	Fatty acid desaturase	343
638024750	160	26.62	13	160	11	148	8.0e-12	63.6	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
638024754	201	37.13	1	167	2	152	2.0e-41	162	COG0242	Peptide deformylase	168
638024756	306	25.41	56	285	44	273	2.0e-16	80.1	COG1234	Ribonuclease BN, tRNA processing enzyme	292
638024757	385	31.68	6	376	2	376	3.0e-49	189	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
638024762	134	39.18	10	103	6	101	3.0e-19	87.7	COG3695	Alkylated DNA nucleotide flippase Atl1, participates in nucleotide excision repair, Ada-like DNA-binding domain	103
638024763	176	29.33	12	148	11	156	1.0e-10	60	COG1716	Forkhead associated (FHA) domain, binds pSer, pThr, pTyr	191
638024764	172	50	10	161	1	151	1.0e-35	142	COG0782	Transcription elongation factor, GreA/GreB family	151
638024765	669	50.08	3	646	36	668	0.0e+00	775	COG1200	RecG-like helicase	677
638024766	212	50.76	10	206	10	203	1.0e-56	213	COG2518	Protein-L-isoaspartate O-methyltransferase	209
638024768	446	37.76	30	407	22	377	6.0e-75	275	COG0498	Threonine synthase	411
638024769	373	41.1	221	373	13	173	1.0e-28	120	COG0807	GTP cyclohydrolase II	193
638024769	373	61.39	7	208	3	203	3.0e-83	302	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
638024771	221	43.19	14	219	3	203	3.0e-44	171	COG0125	Thymidylate kinase	208
638024774	821	46	22	71	2	50	2.0e-09	58.5	COG3350	Uncharacterized conserved protein, YHS domain	53
638024774	821	51.65	151	818	77	709	0.0e+00	759	COG2217	Cation transport ATPase	713
638024775	197	33.17	1	195	1	190	3.0e-24	105	COG3544	Uncharacterized conserved protein, DUF305 family	190
638024776	345	24.29	33	337	40	339	2.0e-14	73.3	COG3391	DNA-binding beta-propeller fold protein YncE	381
638024777	466	47.21	1	465	1	464	0.0e+00	508	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638024778	491	31.87	159	491	1	332	4.0e-40	159	COG0642	Signal transduction histidine kinase	336
638024779	481	31.41	15	475	4	448	4.0e-65	242	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
638024781	761	50.81	16	752	1	709	0.0e+00	718	COG2217	Cation transport ATPase	713
638024783	486	22.2	49	458	11	444	8.0e-16	78.7	COG1538	Outer membrane protein TolC	457
638024784	440	23.62	68	407	30	358	1.0e-36	147	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
638024785	211	28.32	10	178	4	176	2.0e-20	92.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638024786	74	40.3	6	72	3	69	7.0e-11	58.9	COG2608	Copper chaperone CopZ	71
638024787	793	30.97	32	554	1	461	3.0e-79	290	COG3119	Arylsulfatase A or related enzyme	475
638024788	344	26.67	1	329	3	326	1.0e-44	174	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
638024789	146	30.83	17	145	4	136	2.0e-18	85.5	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
638024790	502	24.22	62	456	41	455	1.0e-22	101	COG1538	Outer membrane protein TolC	457
638024792	178	47.62	7	173	13	179	5.0e-45	173	COG3911	Predicted ATPase	183
638024795	210	34.42	1	202	1	208	1.0e-34	140	COG2808	Predicted FMN-binding regulatory protein PaiB	209
638024796	246	34.58	6	208	4	217	2.0e-36	146	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
638024798	191	32.43	17	191	3	187	2.0e-20	92.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638024799	714	45.4	60	714	6	654	0.0e+00	654	COG3590	Predicted metalloendopeptidase	654
638024801	330	25.15	10	328	21	335	5.0e-30	125	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
638024802	216	23.98	1	195	1	196	1.0e-10	59.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638024803	400	21.93	22	393	31	394	3.0e-17	83.3	COG2814	Predicted arabinose efflux permease, MFS family	394
638024805	422	26.95	51	410	19	372	6.0e-30	125	COG4645	Uncharacterized protein	410
638024808	1029	43.19	1	1022	1	1021	0.0e+00	887	COG3696	Cu/Ag efflux pump CusA	1027
638024809	226	43.91	1	224	1	229	9.0e-55	206	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638024810	452	27.49	124	450	2	328	4.0e-34	139	COG0642	Signal transduction histidine kinase	336
638024811	850	38.6	21	849	109	933	0.0e+00	878	COG0178	Excinuclease UvrABC ATPase subunit	935
638024812	737	26.9	431	720	119	405	5.0e-36	146	COG0840	Methyl-accepting chemotaxis protein	408
638024814	349	26.2	60	347	55	314	7.0e-25	108	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
638024815	360	28.23	15	331	11	338	1.0e-39	157	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
638024818	164	27.03	1	148	1	133	1.0e-16	79.3	COG3791	Uncharacterized conserved protein	133
638024819	388	32.27	23	356	1	342	1.0e-53	204	COG0673	Predicted dehydrogenase	342
638024820	501	30.56	219	464	3	251	2.0e-32	134	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638024821	2216	28.57	209	514	2	304	4.0e-29	125	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
638024822	361	18.09	19	316	11	305	1.0e-16	80.9	COG3239	Fatty acid desaturase	343
638024824	508	57.66	6	501	4	498	0.0e+00	609	COG2986	Histidine ammonia-lyase	498
638024825	425	44.91	1	403	1	447	3.0e-109	389	COG0527	Aspartokinase	447
638024828	393	27.87	56	379	53	398	2.0e-29	123	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
638024831	692	36.65	25	655	3	639	4.0e-123	435	COG0210	Superfamily I DNA or RNA helicase	655
638024832	540	41.02	1	480	1	463	1.0e-111	397	COG0443	Molecular chaperone DnaK (HSP70)	579
638024836	319	27.03	56	307	1	246	4.0e-37	149	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
638024842	417	27.25	3	342	17	347	1.0e-31	130	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
638024843	258	28.49	17	195	5	179	3.0e-25	108	COG2091	Phosphopantetheinyl transferase	223
638024844	270	42.37	29	263	1	234	2.0e-57	215	COG3208	Surfactin synthase thioesterase subunit	244
638024845	185	47.78	1	179	18	195	2.0e-56	211	COG0529	Adenylylsulfate kinase or related kinase	197
638024846	529	24	245	489	3	242	2.0e-22	101	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
638024853	342	25.48	31	339	31	330	9.0e-29	121	COG3239	Fatty acid desaturase	343
638024856	422	34.83	1	400	1	391	3.0e-66	246	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
638024857	348	45.04	1	347	4	352	5.0e-110	391	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
638024859	127	48.39	1	93	2	93	4.0e-25	107	COG0776	Bacterial nucleoid DNA-binding protein	94
638024860	304	18.78	91	292	42	251	8.0e-07	48.1	COG3087	Cell division protein FtsN	264
638024861	120	30.09	6	113	19	127	2.0e-08	50.8	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
638024864	319	38.94	4	311	1	310	3.0e-52	199	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638024865	314	43.27	1	305	1	311	5.0e-64	238	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638024866	603	68.49	1	603	2	602	0.0e+00	1039	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
638024867	418	26.99	174	288	3	165	3.0e-14	73.1	COG0681	Signal peptidase I	166
638024868	297	49.01	1	293	7	308	1.0e-98	353	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
638024869	437	45.79	4	430	2	425	7.0e-124	437	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
638024870	374	60.8	2	374	1	364	0.0e+00	535	COG0505	Carbamoylphosphate synthase small subunit	368
638024872	466	50.42	1	466	4	477	0.0e+00	531	COG0469	Pyruvate kinase	477
638024873	228	40.15	34	169	1	137	4.0e-21	94.9	COG1259	Bifunctional DNase/RNase	151
638024876	618	37.77	18	610	17	610	0.0e+00	488	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
638024877	433	51.5	33	430	3	390	4.0e-127	448	COG0372	Citrate synthase	390
638024878	430	29.61	8	426	5	428	3.0e-51	196	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
638024879	326	35.19	1	311	37	348	2.0e-58	219	COG0337	3-dehydroquinate synthetase	360
638024880	339	48.31	1	330	2	350	1.0e-101	362	COG0082	Chorismate synthase	369
638024881	211	24.52	2	207	4	263	4.0e-14	71.9	COG0169	Shikimate 5-dehydrogenase	283
638024882	153	32.37	2	134	7	144	1.0e-11	62.9	COG0703	Shikimate kinase	172
638024883	229	43.81	4	226	12	235	2.0e-60	225	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
638024884	303	58.43	23	288	20	286	6.0e-94	337	COG2876	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	286
638024885	436	37.16	34	430	44	421	1.0e-69	257	COG1169	Isochorismate synthase EntC	423
638024886	589	40.55	2	581	1	563	0.0e+00	462	COG1165	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase	566
638024887	285	31.29	2	265	9	282	9.0e-20	90.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638024888	307	42.95	16	306	5	299	5.0e-62	231	COG1575	1,4-dihydroxy-2-naphthoate octaprenyltransferase	303
638024889	386	32.03	1	380	1	356	3.0e-49	189	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
638024890	482	40.12	8	482	17	527	6.0e-93	335	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
638024891	541	28.95	4	374	1	372	3.0e-47	183	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
638024894	432	60.51	6	432	2	406	0.0e+00	570	COG0538	Isocitrate dehydrogenase	407
638024895	314	45.02	7	313	1	308	3.0e-91	329	COG0039	Malate/lactate dehydrogenase	313
638024896	626	38.82	10	613	11	559	1.0e-130	460	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
638024897	269	34.45	12	248	1	229	4.0e-59	221	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
638024898	386	61.6	1	386	1	385	0.0e+00	527	COG0045	Succinyl-CoA synthetase, beta subunit	387
638024899	299	68.03	1	293	1	291	2.0e-116	412	COG0074	Succinyl-CoA synthetase, alpha subunit	293
638024900	145	62.96	2	136	1	135	2.0e-54	204	COG0105	Nucleoside diphosphate kinase	135
638024901	378	47.25	26	368	4	343	4.0e-112	398	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
638024902	86	53.01	2	83	1	83	4.0e-24	102	COG0228	Ribosomal protein S16	87
638024903	94	46.05	3	78	1	76	4.0e-18	82.9	COG1837	Predicted RNA-binding protein YlqC, contains KH domain, UPF0109 family	76
638024904	188	36.47	1	169	1	170	5.0e-31	127	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
638024905	247	57.81	7	241	3	237	5.0e-88	317	COG0336	tRNA G37 N-methylase TrmD	240
638024906	127	56.76	1	111	1	111	8.0e-33	132	COG0335	Ribosomal protein L19	115
638024908	126	39.32	9	124	1	114	3.0e-23	100	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
638024909	276	48.19	1	275	3	275	5.0e-82	297	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
638024911	388	24.3	143	347	48	255	8.0e-16	78.3	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
638024912	474	48.81	1	460	4	456	0.0e+00	518	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638024913	294	23.19	10	285	2	265	1.0e-45	177	COG1659	Uncharacterized protein, linocin/CFP29 family	267
638024915	565	30.8	26	547	11	509	2.0e-65	243	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
638024916	548	33.53	49	542	1	469	7.0e-81	295	COG0539	Ribosomal protein S1	541
638024920	314	25.88	8	231	3	223	3.0e-09	56.5	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
638024923	548	36.69	36	527	3	473	2.0e-83	303	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
638024928	722	25.11	15	457	20	458	5.0e-38	153	COG2268	Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain	548
638024930	233	36.24	17	227	9	220	7.0e-37	147	COG4305	Peptidoglycan-binding domain, expansin	232
638024931	592	28.77	209	490	3	292	5.0e-20	93.1	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
638024935	307	27.76	7	267	2	245	6.0e-23	101	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638024939	67	68.66	1	67	1	67	8.0e-24	101	COG1278	Cold shock protein, CspA family	67
638024941	251	44.78	56	243	5	204	1.0e-40	160	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
638024945	367	29.66	12	365	9	355	8.0e-37	148	COG0628	Predicted PurR-regulated permease PerM	355
638024946	235	29.2	1	226	7	201	2.0e-25	109	COG1573	Uracil-DNA glycosylase	202
638024948	642	51.18	51	640	3	581	0.0e+00	689	COG0441	Threonyl-tRNA synthetase	589
638024950	115	66.09	1	115	2	116	7.0e-32	129	COG0292	Ribosomal protein L20	118
638024951	349	51.72	5	348	6	335	5.0e-118	417	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
638024952	815	43.09	154	814	1	650	0.0e+00	608	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
638024953	129	44.57	1	92	2	93	7.0e-27	112	COG0776	Bacterial nucleoid DNA-binding protein	94
638024956	182	43.1	4	118	9	124	2.0e-26	112	COG3727	G:T-mismatch repair DNA endonuclease, very short patch repair protein	150
638024957	401	34.38	8	382	11	368	3.0e-45	175	COG5659	SRSO17 transposase	385
638024963	716	24.78	385	715	2	330	2.0e-23	104	COG0642	Signal transduction histidine kinase	336
638024964	436	28.52	17	303	31	326	4.0e-27	116	COG3344	Retron-type reverse transcriptase	328
638024968	253	30.92	1	246	5	253	1.0e-40	160	COG1484	DNA replication protein DnaC	254
638024969	512	30.42	31	313	1	278	1.0e-31	131	COG4584	Transposase	278
638024970	501	33.46	24	273	23	269	3.0e-26	113	COG4584	Transposase	278
638024971	253	38.91	3	239	9	247	3.0e-39	155	COG1484	DNA replication protein DnaC	254
638024972	401	34.38	8	382	11	368	3.0e-45	175	COG5659	SRSO17 transposase	385
638024974	4567	43.46	275	930	1	642	0.0e+00	493	COG1020	Non-ribosomal peptide synthetase component F	642
638024975	1580	39.76	57	1118	6	1059	0.0e+00	788	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638024976	1507	29.12	1140	1319	7	182	9.0e-13	70.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638024976	1507	39.98	13	1088	4	1045	0.0e+00	791	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638024977	1096	41.86	42	1073	2	1005	0.0e+00	790	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638024979	228	24.65	8	212	1	200	2.0e-11	62.9	COG0625	Glutathione S-transferase	211
638024984	250	41.53	10	241	2	233	6.0e-45	174	COG3208	Surfactin synthase thioesterase subunit	244
638024985	425	26.62	10	419	1	381	1.0e-39	157	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638024986	1026	42.97	5	1011	1	1003	0.0e+00	798	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638024987	1540	47.27	16	900	2	881	0.0e+00	808	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638024988	343	28.21	22	329	16	331	9.0e-41	161	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
638024990	5741	46.53	2354	3008	1	642	0.0e+00	517	COG1020	Non-ribosomal peptide synthetase component F	642
638024991	4375	26.06	1751	2075	18	334	1.0e-25	114	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
638024991	4375	40.02	10	994	6	990	0.0e+00	734	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638024991	4375	44.33	2515	3159	1	642	0.0e+00	487	COG1020	Non-ribosomal peptide synthetase component F	642
638024992	11939	46.97	2383	3034	1	642	0.0e+00	521	COG1020	Non-ribosomal peptide synthetase component F	642
638024994	640	19.02	231	555	78	312	6.0e-16	79.6	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
638024995	271	45.14	13	267	12	265	2.0e-63	235	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
638024996	424	33.72	22	421	5	432	2.0e-79	289	COG0001	Glutamate-1-semialdehyde aminotransferase	432
638024997	408	27.13	6	392	7	389	6.0e-30	125	COG2814	Predicted arabinose efflux permease, MFS family	394
638024998	450	65.84	5	441	4	445	0.0e+00	647	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
638024999	1454	34.55	1083	1439	1	382	3.0e-59	224	COG3320	Thioester reductase domain of alpha aminoadipate reductase Lys2 and NRPSs	382
638024999	1454	34.7	236	885	1	642	4.0e-96	347	COG1020	Non-ribosomal peptide synthetase component F	642
638025000	299	51.63	1	215	1	215	3.0e-79	288	COG1535	Isochorismate hydrolase	218
638025000	299	53.73	222	288	1	67	1.0e-17	84.2	COG3433	Aryl carrier domain	74
638025001	548	61.42	5	535	4	537	0.0e+00	757	COG1021	Non-ribosomal peptide synthetase component E (peptide arylation enzyme)	542
638025002	414	39.55	17	406	28	421	8.0e-98	350	COG1169	Isochorismate synthase EntC	423
638025003	257	42.53	1	254	1	251	2.0e-35	142	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638025004	836	18.06	497	835	56	419	9.0e-13	69.4	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
638025006	845	19.54	441	845	1	419	4.0e-19	90.6	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
638025008	384	34.05	23	380	3	368	3.0e-48	186	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
638025009	1067	25.79	600	1001	9	384	3.0e-42	167	COG0247	Fe-S oxidoreductase	388
638025009	1067	28.19	48	562	8	458	5.0e-61	230	COG0277	FAD/FMN-containing dehydrogenase	459
638025010	594	34.33	4	563	3	548	4.0e-120	425	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
638025015	158	30.77	26	142	13	123	7.0e-09	53.4	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
638025016	186	29.1	1	181	6	191	3.0e-29	121	COG4430	Uncharacterized conserved protein YdeI, YjbR/CyaY-like superfamily, DUF1801 family	200
638025017	296	29.05	125	295	5	183	4.0e-20	92.3	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638025018	334	36.22	23	334	45	313	1.0e-45	177	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
638025021	106	45.71	1	105	2	106	7.0e-19	85.5	COG2076	Multidrug transporter EmrE and related cation transporters	106
638025022	376	32.09	92	355	2	252	2.0e-42	166	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
638025024	510	28.73	149	510	51	408	5.0e-37	149	COG0840	Methyl-accepting chemotaxis protein	408
638025026	101	51.22	13	94	1	82	3.0e-17	80.2	COG5552	Uncharacterized protein	88
638025027	1028	48.78	1	1017	1	1019	0.0e+00	1082	COG3696	Cu/Ag efflux pump CusA	1027
638025028	520	31.98	170	502	25	361	2.0e-29	124	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
638025031	169	27.42	17	139	4	127	8.0e-09	53.8	COG0526	Thiol-disulfide isomerase or thioredoxin	127
638025034	332	28.88	1	319	1	317	2.0e-42	166	COG0142	Geranylgeranyl pyrophosphate synthase	322
638025035	198	25.64	23	178	3	154	2.0e-14	72.3	COG1510	DNA-binding transcriptional regulator GbsR, MarR family	177
638025038	734	57.21	102	733	1	628	0.0e+00	750	COG0296	1,4-alpha-glucan branching enzyme	628
638025039	444	34.81	127	443	96	431	4.0e-56	212	COG3281	Predicted trehalose synthase	438
638025040	551	35.62	11	513	1	505	5.0e-85	309	COG0366	Glycosidase	505
638025042	199	39.33	16	193	1	176	1.0e-24	106	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638025048	476	45.4	132	475	120	460	2.0e-94	339	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638025049	633	23.31	16	396	2	380	1.0e-38	155	COG0515	Serine/threonine protein kinase	384
638025050	730	21.97	237	687	3	495	2.0e-39	157	COG0366	Glycosidase	505
638025053	242	21.22	1	236	2	244	1.0e-09	57	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
638025055	105	36.84	1	76	8	81	2.0e-10	57.4	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
638025057	172	45.71	24	163	2	140	5.0e-34	137	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
638025058	171	33.62	34	149	14	126	1.0e-09	56.1	COG0526	Thiol-disulfide isomerase or thioredoxin	127
638025059	93	33.33	1	93	21	113	3.0e-10	56.5	COG2919	Cell division protein FtsB	117
638025061	756	41.38	326	756	29	481	2.0e-98	353	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
638025063	199	27.71	27	189	31	194	3.0e-08	51.8	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
638025065	718	21.49	26	381	2	375	7.0e-24	106	COG0515	Serine/threonine protein kinase	384
638025066	223	39.17	7	223	2	211	1.0e-44	172	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
638025067	437	33.88	21	437	14	435	2.0e-75	276	COG0612	Predicted Zn-dependent peptidase	438
638025068	479	32.18	38	462	7	436	7.0e-72	265	COG0612	Predicted Zn-dependent peptidase	438
638025069	234	36.49	3	218	77	289	2.0e-42	165	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
638025072	271	45.8	10	271	2	263	3.0e-57	215	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
638025073	245	49.37	1	239	8	246	3.0e-83	301	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
638025074	509	22.07	1	281	1	282	3.0e-20	93.6	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
638025075	308	23.2	2	293	1	309	5.0e-15	75.6	COG0524	Sugar or nucleoside kinase, ribokinase family	311
638025078	280	33.33	8	276	1	239	5.0e-45	175	COG0688	Phosphatidylserine decarboxylase	239
638025079	425	42.56	3	421	2	428	2.0e-125	442	COG0124	Histidyl-tRNA synthetase	429
638025085	308	51.02	8	300	2	295	3.0e-83	301	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
638025086	248	33.33	61	233	12	183	2.0e-18	86.4	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
638025087	326	40.21	27	313	9	299	7.0e-63	234	COG3781	Predicted membrane chloride channel, bestrophin family	306
638025093	428	33.71	81	424	5	355	8.0e-56	211	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
638025097	324	32.87	35	319	6	256	7.0e-47	181	COG1830	Fructose-bisphosphate aldolase class Ia, DhnA family	265
638025098	584	20.79	121	577	11	443	6.0e-27	116	COG1538	Outer membrane protein TolC	457
638025099	201	27.89	1	179	13	201	6.0e-19	87.6	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
638025100	333	30	1	333	1	314	1.0e-37	150	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638025102	512	44.53	18	388	15	388	3.0e-107	382	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
638025103	885	21.71	60	853	5	727	4.0e-46	180	COG1033	Predicted exporter protein, RND superfamily	727
638025105	396	36.05	20	394	20	390	1.0e-87	317	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
638025110	654	19.76	44	263	24	267	9.0e-06	45.8	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
638025111	258	41.34	1	252	4	255	3.0e-46	179	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638025113	513	44.31	13	513	20	526	0.0e+00	549	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
638025114	381	46.91	1	379	1	388	1.0e-96	346	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638025116	260	45.65	10	239	2	229	3.0e-61	228	COG0571	dsRNA-specific ribonuclease	235
638025117	268	45.66	73	238	1	158	5.0e-43	168	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
638025118	198	42.69	29	193	1	156	1.0e-40	160	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
638025119	314	50	4	314	1	296	4.0e-99	354	COG1159	GTPase Era, involved in 16S rRNA processing	298
638025120	459	52.6	1	442	2	439	0.0e+00	534	COG1160	Predicted GTPases	444
638025124	294	25.46	2	243	3	268	5.0e-22	98.5	COG3359	Uncharacterized conserved protein YprB, contains RNaseH-like and TPR domains	278
638025127	806	19.2	413	806	1	419	3.0e-21	97.9	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
638025129	517	47.45	6	195	2	195	8.0e-57	215	COG0518	GMP synthase - Glutamine amidotransferase domain	198
638025129	517	70.75	200	517	2	315	0.0e+00	535	COG0519	GMP synthase, PP-ATPase domain/subunit	315
638025131	485	32.42	255	473	1	169	2.0e-34	140	COG0516	IMP dehydrogenase/GMP reductase	170
638025131	485	37.5	94	199	5	116	6.0e-15	76	COG0517	CBS domain	117
638025132	772	42.77	177	672	4	478	3.0e-122	433	COG0443	Molecular chaperone DnaK (HSP70)	579
638025133	14274	42.18	6432	7366	6	932	0.0e+00	765	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638025135	259	27.27	1	209	3	208	6.0e-30	124	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
638025137	171	52.63	1	171	2	171	7.0e-56	209	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
638025138	462	46.07	1	437	2	437	0.0e+00	464	COG0621	tRNA A37 methylthiotransferase MiaB	437
638025140	493	24.84	25	493	7	395	1.0e-31	131	COG3552	Uncharacterized conserved protein, contains von Willebrand factor type A (vWA) domain	395
638025141	431	32.95	9	423	5	432	1.0e-77	284	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
638025143	218	61.75	3	218	6	222	4.0e-82	297	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
638025144	232	61.93	1	218	1	218	4.0e-86	310	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
638025145	393	45.93	3	393	2	391	5.0e-84	305	COG0183	Acetyl-CoA acetyltransferase	392
638025146	799	23.4	403	799	58	442	4.0e-25	110	COG2319	WD40 repeat	466
638025147	570	53.61	14	566	1	540	0.0e+00	535	COG0539	Ribosomal protein S1	541
638025149	381	49.49	1	381	1	391	1.0e-94	340	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638025151	380	48.33	1	380	1	389	5.0e-101	361	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638025153	258	49.42	1	253	2	256	1.0e-53	203	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638025154	282	50.88	1	282	1	283	2.0e-90	326	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
638025157	361	43.37	40	315	1	265	3.0e-55	209	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
638025163	360	40.82	11	352	2	331	7.0e-71	261	COG0430	RNA 3'-terminal phosphate cyclase	341
638025164	645	30.9	46	641	16	562	6.0e-82	298	COG2936	Predicted acyl esterase	563
638025165	477	50.65	10	470	4	457	0.0e+00	463	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638025166	451	24.4	110	439	2	334	6.0e-33	135	COG0642	Signal transduction histidine kinase	336
638025167	203	29.59	15	202	6	198	3.0e-34	138	COG4430	Uncharacterized conserved protein YdeI, YjbR/CyaY-like superfamily, DUF1801 family	200
638025169	435	22.92	130	416	109	391	5.0e-10	59.4	COG2814	Predicted arabinose efflux permease, MFS family	394
638025171	332	32.41	4	327	2	309	9.0e-47	181	COG0385	Predicted Na+-dependent transporter	319
638025175	523	19.93	1	512	2	534	4.0e-31	129	COG2303	Choline dehydrogenase or related flavoprotein	542
638025176	787	23.15	1	511	4	528	2.0e-39	158	COG2303	Choline dehydrogenase or related flavoprotein	542
638025178	150	27.4	11	133	3	148	1.0e-08	52.7	COG2165	Type II secretory pathway, pseudopilin PulG	149
638025179	233	30.73	1	185	1	187	7.0e-25	107	COG0518	GMP synthase - Glutamine amidotransferase domain	198
638025182	289	52.6	1	289	1	289	3.0e-101	361	COG1946	Acyl-CoA thioesterase	289
638025183	307	32.29	8	294	37	316	2.0e-42	166	COG0385	Predicted Na+-dependent transporter	319
638025185	160	47.44	1	155	1	155	2.0e-35	142	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
638025187	779	37.07	1	745	20	765	0.0e+00	518	COG1205	ATP-dependent helicase YprA,  contains C-terminal metal-binding DUF1998 domain	851
638025188	419	36.68	4	413	4	422	7.0e-60	225	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
638025193	745	44.63	3	237	2	243	2.0e-67	250	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
638025194	329	43.93	72	242	2	172	3.0e-34	139	COG1386	Chromosome segregation and condensation protein ScpB	184
638025195	289	38.67	24	276	2	244	2.0e-38	153	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
638025196	347	40.72	1	328	6	314	2.0e-81	295	COG0180	Tryptophanyl-tRNA synthetase	314
638025198	310	53.56	1	294	5	299	7.0e-98	350	COG4974	Site-specific recombinase XerD	300
638025200	203	42.65	3	203	1	203	7.0e-51	193	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
638025201	432	22.17	26	429	1	396	4.0e-12	66.4	COG0475	Kef-type K+ transport system, membrane component KefB	397
638025205	257	25.6	19	220	12	217	4.0e-16	78.8	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
638025206	358	24.9	42	281	4	246	3.0e-16	79.7	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
638025207	207	22.14	27	155	3	128	3.0e-06	45.3	COG4319	Ketosteroid isomerase homolog	137
638025210	319	22.36	16	305	21	341	1.0e-23	103	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
638025211	597	34.33	4	563	3	548	9.0e-121	427	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
638025212	119	43.36	1	113	1	112	8.0e-22	95.7	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
638025213	501	39.41	6	499	4	501	1.0e-66	247	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
638025214	157	32.45	7	157	8	158	4.0e-22	97.6	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
638025215	93	35.8	5	85	3	83	2.0e-10	57.4	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
638025216	123	37.96	1	106	3	110	3.0e-16	77.6	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
638025219	207	34.15	2	206	15	205	6.0e-27	114	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
638025220	545	44.44	20	524	5	516	4.0e-124	438	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
638025221	346	33.33	10	234	19	247	1.0e-39	157	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
638025226	474	22.84	48	451	17	392	3.0e-17	83.5	COG5557	Ni/Fe-hydrogenase 2 integral membrane subunit HybB	401
638025227	988	26.81	748	979	2	193	4.0e-35	144	COG0437	Fe-S-cluster-containing dehydrogenase component	203
638025229	426	43.1	8	410	3	407	5.0e-87	315	COG1301	Na+/H+-dicarboxylate symporter	415
638025230	405	29.14	41	363	1	296	5.0e-33	135	COG3491	Isopenicillin N synthase and related dioxygenases	322
638025232	421	20.35	64	396	59	392	6.0e-11	62.5	COG2814	Predicted arabinose efflux permease, MFS family	394
638025233	1164	57.35	3	1163	4	1147	0.0e+00	1561	COG1038	Pyruvate carboxylase	1149
638025234	156	33.33	9	156	30	174	6.0e-13	67	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
638025235	784	22.48	23	778	38	834	5.0e-53	203	COG3188	Outer membrane usher protein FimD/PapC	835
638025236	255	18.7	21	245	19	232	1.0e-13	70.4	COG3121	P pilus assembly protein, chaperone PapD	235
638025237	185	36	12	185	14	174	1.0e-10	59.6	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
638025238	599	34.88	335	592	4	231	3.0e-47	183	COG0860	N-acetylmuramoyl-L-alanine amidase	231
638025244	185	39.66	15	183	5	178	4.0e-30	124	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
638025246	76	55.71	5	74	10	79	9.0e-09	51.9	COG0236	Acyl carrier protein	80
638025248	671	23.89	40	665	2	530	1.0e-48	188	COG1574	Predicted amidohydrolase YtcJ	535
638025249	893	47.85	11	889	4	842	0.0e+00	896	COG0249	DNA mismatch repair ATPase MutS	843
638025250	449	43.03	26	447	7	390	2.0e-101	362	COG3004	Na+/H+ antiporter NhaA	390
638025251	563	36.44	1	496	2	505	3.0e-101	362	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
638025255	1041	38.89	2	1006	1	1008	0.0e+00	886	COG0841	Multidrug efflux pump subunit AcrB	1009
638025256	395	35.23	26	373	22	372	4.0e-25	109	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
638025257	469	29.23	34	461	16	443	2.0e-26	114	COG1538	Outer membrane protein TolC	457
638025260	232	35.12	1	230	2	243	1.0e-45	176	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
638025261	257	35.16	1	254	9	264	1.0e-29	123	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
638025262	248	35.71	8	243	26	262	6.0e-31	127	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
638025263	235	38.68	2	235	13	251	3.0e-40	158	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
638025264	336	23.76	8	301	12	297	3.0e-15	76.3	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
638025265	602	37.96	28	566	13	513	1.0e-117	417	COG0513	Superfamily II DNA and RNA helicase	513
638025266	442	22.95	3	425	4	389	5.0e-37	148	COG3182	Uncharacterized iron-regulated membrane protein	442
638025267	299	23.29	51	299	8	244	6.0e-10	58.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
638025268	162	24.8	1	124	4	124	2.0e-06	45	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
638025269	1521	57.98	708	1199	1	483	0.0e+00	632	COG0069	Glutamate synthase domain 2	485
638025270	486	43.29	22	477	1	457	1.0e-128	453	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
638025272	315	28.63	63	312	2	254	1.0e-35	143	COG1192	Cellulose biosynthesis protein BcsQ	259
638025273	102	41.67	19	102	23	106	2.0e-16	77.5	COG4654	Cytochrome c551/c552	110
638025274	385	28.8	14	383	1	372	8.0e-24	105	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
638025275	1055	29.79	2	1039	1	1009	0.0e+00	636	COG0841	Multidrug efflux pump subunit AcrB	1009
638025277	526	23.12	7	519	11	539	3.0e-38	153	COG2303	Choline dehydrogenase or related flavoprotein	542
638025279	172	22.58	2	142	4	157	3.0e-08	51.5	COG1443	Isopentenyldiphosphate isomerase	185
638025280	332	24.4	43	288	22	264	8.0e-24	104	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
638025281	346	28.73	159	328	22	201	1.0e-18	87.7	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
638025282	175	29.56	1	158	3	155	8.0e-23	100	COG0597	Lipoprotein signal peptidase	167
638025284	3037	30.85	499	1601	1	1059	0.0e+00	587	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638025285	5150	30.36	2989	4032	3	1030	0.0e+00	683	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638025286	485	19.75	44	365	11	296	2.0e-27	117	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
638025287	8982	29.63	6674	7724	6	1053	0.0e+00	630	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638025289	366	27.05	40	363	16	333	9.0e-34	138	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
638025291	247	29.55	1	242	2	247	5.0e-33	134	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638025292	262	31.35	9	254	2	252	9.0e-31	127	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638025293	417	30.19	10	412	6	410	5.0e-64	238	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
638025294	657	43.29	365	652	5	302	2.0e-74	273	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
638025295	487	29.96	37	484	1	410	9.0e-64	238	COG2124	Cytochrome P450	411
638025296	171	29.94	15	167	12	162	8.0e-24	103	COG0597	Lipoprotein signal peptidase	167
638025297	416	28.54	9	416	3	377	4.0e-64	239	COG3425	3-hydroxy-3-methylglutaryl CoA synthase	377
638025300	420	28.95	4	419	3	377	3.0e-79	289	COG3425	3-hydroxy-3-methylglutaryl CoA synthase	377
638025302	168	23.7	11	166	5	177	2.0e-08	52.2	COG0250	Transcription antitermination factor NusG	178
638025303	292	18.73	22	267	12	248	6.0e-22	98.2	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
638025304	529	27.33	40	192	15	174	6.0e-11	62.7	COG2203	GAF domain	175
638025307	727	32.23	147	413	1	298	2.0e-43	171	COG0515	Serine/threonine protein kinase	384
638025308	577	32.35	330	566	2	217	3.0e-32	133	COG2114	Adenylate cyclase, class 3	227
638025310	544	23.84	1	396	23	406	5.0e-45	175	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
638025311	221	32.78	41	219	1	180	4.0e-25	108	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638025314	466	22.71	177	464	6	335	2.0e-15	77.9	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
638025315	505	30.65	116	486	2	385	8.0e-57	215	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
638025316	318	23.55	60	307	2	239	2.0e-10	60.3	COG3591	V8-like Glu-specific endopeptidase	251
638025317	286	37.4	3	259	1	261	6.0e-48	184	COG0300	Short-chain dehydrogenase	265
638025318	153	35.33	1	148	2	151	4.0e-17	80.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
638025321	263	29.58	20	255	6	244	1.0e-24	107	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
638025322	260	42.8	1	256	1	260	4.0e-70	258	COG0708	Exonuclease III	261
638025324	322	25.93	37	302	19	279	2.0e-14	73.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638025330	553	25.94	52	441	12	391	4.0e-36	146	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638025334	1013	40.59	1	990	2	1043	0.0e+00	989	COG0587	DNA polymerase III, alpha subunit	1139
638025335	160	36.03	10	145	7	139	2.0e-14	71.9	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
638025336	368	38.7	4	292	3	272	3.0e-42	166	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
638025338	500	28.57	1	500	1	518	1.0e-72	267	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
638025339	324	34.76	1	318	1	308	2.0e-51	195	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638025342	470	22.05	7	309	39	354	4.0e-12	66.5	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
638025345	827	56.09	33	802	10	781	0.0e+00	1032	COG0466	ATP-dependent Lon protease, bacterial type	782
638025351	287	21.43	30	275	15	230	8.0e-17	81.2	COG0860	N-acetylmuramoyl-L-alanine amidase	231
638025352	4528	41.63	3432	4081	1	642	7.0e-128	454	COG1020	Non-ribosomal peptide synthetase component F	642
638025353	3780	41.64	2491	3139	1	642	5.0e-128	454	COG1020	Non-ribosomal peptide synthetase component F	642
638025353	3780	45.69	12	905	6	893	0.0e+00	755	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638025354	1777	39.71	920	1584	1	642	1.0e-117	418	COG1020	Non-ribosomal peptide synthetase component F	642
638025355	326	46.18	1	325	1	315	1.0e-91	330	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
638025356	377	31.98	204	364	37	202	2.0e-09	57.3	COG1573	Uracil-DNA glycosylase	202
638025362	177	29.56	8	163	2	160	4.0e-17	81.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638025368	361	39.84	1	361	3	346	9.0e-80	290	COG0205	6-phosphofructokinase	347
638025369	643	28.93	12	308	2	312	2.0e-42	167	COG0515	Serine/threonine protein kinase	384
638025371	630	35.66	107	617	7	548	6.0e-110	391	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
638025377	619	36.58	1	617	1	634	0.0e+00	464	COG0323	DNA mismatch repair ATPase MutL	638
638025378	320	22.84	12	319	2	306	4.0e-20	92.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638025379	573	32.46	343	558	40	254	2.0e-19	91.5	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
638025383	504	29.05	196	371	33	204	4.0e-21	96.4	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
638025385	711	31.68	397	689	3	288	9.0e-19	89.4	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
638025386	220	30.66	3	210	1	210	6.0e-24	104	COG0625	Glutathione S-transferase	211
638025387	166	31.36	1	118	1	116	6.0e-19	87	COG1733	DNA-binding transcriptional regulator, HxlR family	120
638025388	230	49.1	6	227	5	222	3.0e-61	228	COG0283	Cytidylate kinase	222
638025389	363	44.57	8	362	5	352	9.0e-92	330	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
638025390	322	66.35	9	320	5	316	0.0e+00	484	COG0825	Acetyl-CoA carboxylase alpha subunit	317
638025392	655	29.58	7	308	4	301	6.0e-36	146	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
638025393	484	52.42	1	446	2	454	0.0e+00	519	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638025395	150	47.76	6	132	7	140	1.0e-40	158	COG2131	Deoxycytidylate deaminase	164
638025397	748	21.65	26	746	20	646	1.0e-33	138	COG2766	Predicted Ser/Thr protein kinase	649
638025398	506	43.8	5	504	6	480	2.0e-128	452	COG0443	Molecular chaperone DnaK (HSP70)	579
638025399	689	29.89	48	310	2	277	2.0e-39	157	COG0515	Serine/threonine protein kinase	384
638025401	828	47.68	8	827	5	814	0.0e+00	953	COG0495	Leucyl-tRNA synthetase	814
638025402	510	34.84	19	503	1	475	8.0e-75	274	COG1233	Phytoene dehydrogenase-related protein	487
638025403	1764	22.74	1445	1764	46	330	3.0e-29	125	COG0642	Signal transduction histidine kinase	336
638025403	1764	33.02	299	1143	2	849	0.0e+00	465	COG3899	Predicted ATPase	849
638025404	425	64.18	12	425	1	404	0.0e+00	631	COG1219	ATP-dependent protease Clp, ATPase subunit	408
638025407	281	33.47	11	256	4	246	2.0e-43	170	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
638025413	298	45.56	17	275	6	261	1.0e-70	259	COG1606	ATP-utilizing enzyme, PP-loop superfamily	269
638025414	257	37.99	1	177	18	196	5.0e-46	178	COG0529	Adenylylsulfate kinase or related kinase	197
638025415	137	26.83	5	127	5	118	8.0e-08	49.8	COG1310	Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif	134
638025417	90	27.96	1	90	1	84	1.0e-07	48.4	COG1977	Molybdopterin converting factor, small subunit	84
638025418	79	31.17	1	76	1	76	2.0e-08	50.6	COG0425	TusA-related sulfurtransferase	78
638025419	255	47.37	17	203	27	216	3.0e-47	182	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
638025421	427	28.84	59	423	1	364	1.0e-45	177	COG4585	Signal transduction histidine kinase	365
638025422	246	37.55	17	245	1	210	8.0e-46	177	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
638025424	293	32.99	1	284	3	289	8.0e-62	230	COG1131	ABC-type multidrug transport system, ATPase component	293
638025427	2152	31.89	1749	1926	4	187	2.0e-13	73.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638025427	2152	42.39	10	1080	4	1043	0.0e+00	814	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638025428	3048	42.23	1772	2414	1	642	0.0e+00	474	COG1020	Non-ribosomal peptide synthetase component F	642
638025429	4465	45.44	3363	4005	1	642	0.0e+00	486	COG1020	Non-ribosomal peptide synthetase component F	642
638025430	154	31.76	6	152	5	150	2.0e-07	48.8	COG5528	Uncharacterized membrane protein	155
638025431	501	41.94	1	473	29	507	1.0e-123	436	COG0513	Superfamily II DNA and RNA helicase	513
638025432	702	54.12	1	701	1	692	0.0e+00	799	COG0480	Translation elongation factor EF-G, a GTPase	697
638025436	398	33.93	134	397	6	283	7.0e-39	154	COG1408	Predicted phosphohydrolase, MPP superfamily	284
638025437	254	47.49	3	254	9	265	8.0e-35	140	COG0428	Zinc transporter ZupT	266
638025438	174	35.06	1	169	6	179	1.0e-24	105	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638025443	385	26.59	10	339	16	342	5.0e-33	135	COG0628	Predicted PurR-regulated permease PerM	355
638025446	450	40.28	15	361	1	341	2.0e-74	273	COG3191	L-aminopeptidase/D-esterase	348
638025447	729	29.57	380	666	24	313	2.0e-42	167	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
638025450	335	62.69	12	335	1	327	0.0e+00	506	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
638025452	307	33.88	6	304	3	292	5.0e-60	224	COG1131	ABC-type multidrug transport system, ATPase component	293
638025460	311	30.64	6	300	2	292	2.0e-26	113	COG0583	DNA-binding transcriptional regulator, LysR family	297
638025461	312	36.08	21	308	3	276	7.0e-53	200	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
638025463	423	20.85	96	401	42	315	2.0e-22	100	COG0668	Small-conductance mechanosensitive channel	316
638025473	547	28.61	100	475	1	367	7.0e-38	152	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
638025474	414	36.89	1	407	16	411	4.0e-69	255	COG2124	Cytochrome P450	411
638025477	1399	35.07	516	896	42	442	1.0e-52	202	COG2319	WD40 repeat	466
638025483	488	22.17	33	449	4	397	4.0e-36	146	COG0415	Deoxyribodipyrimidine photolyase	461
638025485	593	39.41	9	273	4	265	1.0e-55	211	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
638025486	334	38.56	39	332	39	344	3.0e-60	225	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
638025488	417	33.23	94	415	89	407	6.0e-31	128	COG0840	Methyl-accepting chemotaxis protein	408
638025490	160	32.67	3	151	6	153	3.0e-21	95	COG0835	Chemotaxis signal transduction protein	165
638025491	290	29.91	166	272	4	108	6.0e-15	74.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
638025493	374	58.33	1	372	1	371	0.0e+00	483	COG0686	Alanine dehydrogenase	371
638025494	213	35.16	1	182	4	177	2.0e-31	129	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638025495	302	21.93	1	256	2	252	2.0e-12	67	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
638025498	256	47.64	1	253	1	251	4.0e-75	274	COG1521	Pantothenate kinase type III	251
638025499	334	42.98	94	327	1	233	2.0e-63	236	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
638025503	550	23.6	229	470	16	276	3.0e-08	53.7	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
638025505	343	29.23	1	342	12	367	4.0e-41	162	COG2021	Homoserine acetyltransferase	368
638025506	211	48.77	3	205	7	209	6.0e-63	233	COG0572	Uridine kinase	218
638025507	562	23.1	27	299	7	268	7.0e-21	95.7	COG3220	Uncharacterized conserved protein, UPF0276 family	282
638025511	232	45.06	5	232	1	228	8.0e-55	207	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638025512	526	26.04	194	525	6	334	7.0e-32	132	COG0642	Signal transduction histidine kinase	336
638025518	330	48.51	10	310	7	300	1.0e-91	330	COG0031	Cysteine synthase	300
638025519	410	29.19	20	408	2	417	3.0e-38	152	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
638025520	412	28.16	26	412	1	419	1.0e-30	127	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
638025521	250	50.45	10	227	1	220	3.0e-79	288	COG1136	ABC-type lipoprotein export system, ATPase component	226
638025522	419	30.9	56	312	50	346	4.0e-25	109	COG1566	Multidrug resistance efflux pump	352
638025523	448	24.11	5	448	8	451	7.0e-29	121	COG1538	Outer membrane protein TolC	457
638025525	839	46.27	252	839	148	784	0.0e+00	620	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
638025526	271	28.46	2	257	15	279	8.0e-18	84.3	COG5495	Predicted oxidoreductase, contains short-chain dehydrogenase (SDR) and DUF2520 domains	289
638025532	190	32.81	7	184	5	195	1.0e-35	142	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
638025534	406	42.89	12	405	21	409	3.0e-112	398	COG3876	Uncharacterized conserved protein YbbC, DUF1343 family	409
638025535	456	27.75	15	199	38	227	5.0e-21	96	COG2114	Adenylate cyclase, class 3	227
638025537	801	31.23	7	799	1	753	6.0e-115	408	COG1193	dsDNA-specific endonuclease/ATPase MutS2	753
638025539	266	22.16	49	237	21	204	3.0e-08	52.7	COG2091	Phosphopantetheinyl transferase	223
638025543	450	52.43	1	447	4	454	0.0e+00	472	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638025544	429	33.33	200	427	94	330	8.0e-30	125	COG0642	Signal transduction histidine kinase	336
638025545	431	31.84	30	428	44	443	1.0e-35	144	COG1538	Outer membrane protein TolC	457
638025546	227	47.79	2	225	1	226	6.0e-82	297	COG1136	ABC-type lipoprotein export system, ATPase component	226
638025547	482	24.58	61	294	52	341	8.0e-17	81.9	COG1566	Multidrug resistance efflux pump	352
638025548	401	30.95	16	401	1	419	8.0e-38	151	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
638025553	253	35.63	3	243	5	246	2.0e-42	166	COG0300	Short-chain dehydrogenase	265
638025554	399	32.75	132	399	2	283	2.0e-39	157	COG1408	Predicted phosphohydrolase, MPP superfamily	284
638025557	1182	43.07	156	802	57	704	0.0e+00	560	COG0557	Exoribonuclease R	706
638025559	410	48.02	7	407	6	402	3.0e-99	355	COG0303	Molybdopterin biosynthesis enzyme	404
638025560	224	55.21	19	210	3	193	1.0e-62	232	COG0807	GTP cyclohydrolase II	193
638025561	277	20.86	1	277	4	269	1.0e-32	133	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
638025562	357	27.56	220	345	4	125	1.0e-09	58.1	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
638025562	357	40.89	1	225	8	220	3.0e-59	222	COG0321	Lipoate-protein ligase B	221
638025564	416	48.79	2	413	1	403	2.0e-108	385	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
638025565	309	55.22	1	297	7	302	1.0e-115	409	COG0320	Lipoate synthase	306
638025566	465	45.95	1	455	1	454	0.0e+00	495	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
638025569	202	43.48	109	199	1	87	4.0e-14	71.7	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
638025569	202	57.43	4	102	8	107	3.0e-33	135	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
638025570	259	36.08	8	253	5	259	6.0e-46	177	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
638025571	253	61.81	1	250	1	254	4.0e-99	354	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
638025572	178	40.74	3	173	7	195	1.0e-44	172	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
638025573	238	34.06	1	228	2	230	1.0e-51	196	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
638025574	197	46.34	1	196	2	204	1.0e-52	199	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
638025575	345	42.09	5	345	3	353	8.0e-68	251	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
638025576	437	49.64	16	433	2	419	8.0e-124	437	COG0141	Histidinol dehydrogenase	425
638025577	286	44.14	1	285	1	289	9.0e-76	277	COG0040	ATP phosphoribosyltransferase	290
638025578	372	36.25	1	371	2	386	8.0e-44	171	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
638025579	411	35.73	1	354	7	360	1.0e-70	261	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
638025580	334	42.64	16	331	1	321	3.0e-86	312	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
638025581	112	31.82	2	112	12	143	1.0e-11	61.9	COG3296	Uncharacterized conserved protein, Tic20 family	143
638025582	624	67.98	141	594	1	432	0.0e+00	770	COG0422	Thiamine biosynthesis protein ThiC	432
638025583	143	42.98	4	122	1	117	3.0e-17	81	COG0517	CBS domain	117
638025584	463	26.75	29	462	10	461	6.0e-26	112	COG0471	Di- and tricarboxylate transporter	461
638025587	471	51.75	1	449	2	454	0.0e+00	505	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638025589	143	27.73	24	142	7	123	1.0e-15	76.1	COG3682	Predicted transcriptional regulator	123
638025590	638	20.7	21	328	11	321	3.0e-14	74.2	COG4219	Signal transducer regulating beta-lactamase production, contains  metallopeptidase domain	337
638025591	368	31.21	45	367	13	330	2.0e-38	153	COG0642	Signal transduction histidine kinase	336
638025594	296	30.82	3	292	1	288	6.0e-29	121	COG0583	DNA-binding transcriptional regulator, LysR family	297
638025596	435	36.71	209	414	10	216	2.0e-39	157	COG5637	Uncharacterized membrane protein	217
638025597	226	55.3	6	222	4	220	9.0e-64	236	COG1926	Predicted phosphoribosyltransferase	220
638025598	707	25.44	421	696	59	333	1.0e-29	125	COG0642	Signal transduction histidine kinase	336
638025599	455	42.95	1	450	2	461	2.0e-119	422	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638025601	620	32.88	463	608	44	188	6.0e-24	106	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
638025603	485	21.53	23	445	17	397	4.0e-17	83.1	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
638025604	594	27.71	141	297	1	165	6.0e-06	46.2	COG2203	GAF domain	175
638025604	594	35.06	428	589	2	175	4.0e-17	83.2	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638025608	452	50	1	452	1	455	0.0e+00	471	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638025609	702	34.34	439	698	81	336	5.0e-35	143	COG0642	Signal transduction histidine kinase	336
638025610	228	24.31	7	187	6	184	4.0e-14	72	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638025611	265	34.63	8	224	7	220	3.0e-33	135	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
638025612	246	24.47	4	224	2	224	1.0e-13	70.2	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
638025613	345	38.08	1	342	4	337	3.0e-74	272	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
638025614	418	35.02	4	414	2	374	8.0e-86	311	COG3425	3-hydroxy-3-methylglutaryl CoA synthase	377
638025615	162	38.35	20	151	11	143	5.0e-25	107	COG0071	Molecular chaperone IbpA, HSP20 family	146
638025617	810	36.02	146	800	26	713	0.0e+00	471	COG2217	Cation transport ATPase	713
638025623	436	32.27	70	436	39	406	2.0e-66	246	COG4826	Serine protease inhibitor	410
638025637	262	43.91	19	247	1	226	5.0e-54	204	COG3208	Surfactin synthase thioesterase subunit	244
638025639	1843	44.88	27	1107	1	1032	0.0e+00	890	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638025641	387	31.11	1	303	1	309	7.0e-39	155	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
638025642	359	16.71	4	333	10	339	2.0e-13	70	COG3621	Patatin-like phospholipase/acyl hydrolase	394
638025643	1435	29.63	1146	1412	1	257	4.0e-26	114	COG3319	Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase	257
638025643	1435	39.64	299	957	1	642	5.0e-124	440	COG1020	Non-ribosomal peptide synthetase component F	642
638025644	1829	43.93	32	1096	3	1032	0.0e+00	840	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638025645	1853	48.54	38	995	5	950	0.0e+00	851	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638025646	2973	25.41	2584	2761	4	188	4.0e-10	62.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638025646	2973	33.18	299	958	1	642	8.0e-116	413	COG1020	Non-ribosomal peptide synthetase component F	642
638025646	2973	40.42	1149	2227	1	1041	0.0e+00	841	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638025649	847	20.95	7	401	4	386	1.0e-13	72.4	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
638025650	461	19.89	1	347	38	369	9.0e-28	118	COG1524	Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily	450
638025651	379	43.04	1	379	1	388	4.0e-80	291	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638025652	504	30.4	1	503	11	527	1.0e-76	281	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
638025653	1229	16.34	8	1118	6	1039	2.0e-08	56.1	COG2911	Autotransporter translocation and assembly factor TamB	1278
638025656	269	33.15	5	188	1	182	1.0e-24	107	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638025659	347	37.69	21	345	6	334	2.0e-53	203	COG2855	Uncharacterized membrane protein YadS	334
638025660	532	28	11	487	2	517	1.0e-62	234	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
638025661	118	44.32	33	117	12	99	7.0e-16	75.7	COG0607	Rhodanese-related sulfurtransferase	110
638025662	253	23.69	4	236	3	247	2.0e-09	56.2	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
638025663	175	37.8	6	169	15	178	4.0e-22	97.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638025666	233	29.86	1	192	13	232	1.0e-22	100	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
638025668	264	34.14	3	248	8	255	2.0e-11	63.1	COG0730	Uncharacterized membrane protein YfcA	258
638025674	509	43.99	117	507	42	410	1.0e-109	390	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
638025677	477	45	70	374	29	346	1.0e-59	224	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
638025678	209	33.71	29	203	19	192	3.0e-20	91.9	COG0576	Molecular chaperone GrpE (heat shock protein)	193
638025680	674	51.06	28	636	4	594	0.0e+00	647	COG0465	ATP-dependent Zn proteases	596
638025682	135	27.91	1	124	7	130	2.0e-06	44.6	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
638025684	1296	30.39	36	298	1	277	6.0e-39	157	COG0515	Serine/threonine protein kinase	384
638025685	459	47.73	133	457	126	456	8.0e-91	328	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638025687	792	24.02	36	781	11	765	1.0e-93	337	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
638025689	551	70.38	3	549	10	555	0.0e+00	901	COG2987	Urocanate hydratase	561
638025691	421	38.06	21	418	15	406	1.0e-78	287	COG1228	Imidazolonepropionase or related amidohydrolase	406
638025692	277	27.73	1	247	1	233	7.0e-23	101	COG0121	Predicted glutamine amidotransferase	252
638025694	152	41.89	2	148	1	147	2.0e-30	124	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
638025695	511	42.23	1	204	1	203	2.0e-41	164	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
638025695	511	46.38	225	499	10	275	4.0e-59	222	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
638025696	126	38.1	3	124	2	126	5.0e-24	103	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
638025697	247	59.66	10	244	2	239	3.0e-81	294	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
638025698	458	47.52	8	457	5	462	4.0e-116	412	COG1109	Phosphomannomutase	464
638025699	291	50.74	13	280	2	265	2.0e-71	262	COG0294	Dihydropteroate synthase	274
638025700	134	22.73	1	129	1	132	5.0e-12	63.5	COG1765	Uncharacterized OsmC-related protein	137
638025701	182	45.35	2	172	21	192	2.0e-43	168	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
638025702	293	34.58	1	288	1	290	5.0e-38	151	COG0583	DNA-binding transcriptional regulator, LysR family	297
638025703	231	39.34	1	231	1	243	1.0e-50	193	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
638025704	308	41.79	10	287	3	276	1.0e-69	256	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
638025705	638	58.46	12	602	5	596	0.0e+00	734	COG0465	ATP-dependent Zn proteases	596
638025706	451	33.9	21	245	16	247	9.0e-36	144	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
638025711	938	20.85	207	938	6	768	1.0e-34	142	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
638025715	263	24.87	55	240	45	228	3.0e-10	59.1	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
638025716	258	37.65	5	250	3	250	3.0e-35	142	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638025717	389	25.31	62	374	24	325	2.0e-21	97.2	COG0515	Serine/threonine protein kinase	384
638025719	613	27.15	17	293	1	289	2.0e-34	141	COG0515	Serine/threonine protein kinase	384
638025730	275	40	1	274	1	295	6.0e-60	224	COG3246	Uncharacterized conserved protein, DUF849 family	298
638025732	261	22.32	8	240	18	225	6.0e-19	88	COG5012	Methanogenic corrinoid protein MtbC1	227
638025735	511	52.71	26	501	16	495	0.0e+00	634	COG0753	Catalase	496
638025739	186	49.48	2	180	10	201	1.0e-46	179	COG1573	Uracil-DNA glycosylase	202
638025740	143	35.25	5	143	4	140	3.0e-20	90.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
638025741	406	50.63	6	401	2	387	5.0e-109	388	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
638025744	424	26.45	272	421	1	150	1.0e-14	74.5	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
638025744	424	39	6	258	9	257	2.0e-54	206	COG0631	Serine/threonine protein phosphatase PrpC	262
638025747	314	22.57	86	309	65	267	7.0e-18	84.9	COG1834	N-Dimethylarginine dimethylaminohydrolase	267
638025748	2742	37.62	1253	1653	35	432	3.0e-98	355	COG0001	Glutamate-1-semialdehyde aminotransferase	432
638025748	2742	40.03	1897	2554	1	642	0.0e+00	479	COG1020	Non-ribosomal peptide synthetase component F	642
638025748	2742	45.88	116	1168	1	1025	0.0e+00	910	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638025750	581	31.16	10	577	12	531	1.0e-88	321	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
638025751	109	57.41	3	109	1	108	1.0e-24	104	COG1742	Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily	109
638025755	320	24.23	141	320	46	237	5.0e-16	78.9	COG3510	Cephalosporin hydroxylase	237
638025759	3906	31.37	14	575	11	530	3.0e-84	309	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
638025759	3906	45.56	914	1582	1	642	0.0e+00	510	COG1020	Non-ribosomal peptide synthetase component F	642
638025760	2502	39.88	1235	1893	1	642	1.0e-120	429	COG1020	Non-ribosomal peptide synthetase component F	642
638025760	2502	44.33	7	928	1	918	0.0e+00	777	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638025761	211	41.98	8	210	31	237	2.0e-44	172	COG3510	Cephalosporin hydroxylase	237
638025765	126	27.12	3	120	9	122	4.0e-11	60.7	COG3607	Predicted lactoylglutathione lyase	133
638025767	190	46.77	2	186	1	185	4.0e-35	141	COG2119	Putative Ca2+/H+ antiporter, TMEM165/GDT1 family	190
638025772	243	26.56	5	242	2	241	3.0e-33	135	COG4464	Tyrosine-protein phosphatase YwqE	254
638025773	97	42.86	26	88	2	64	7.0e-13	65.5	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
638025774	329	42.17	1	327	1	325	8.0e-62	231	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
638025776	345	29.43	15	342	10	304	2.0e-43	169	COG0010	Arginase family enzyme	305
638025778	448	43.9	9	350	12	341	2.0e-64	239	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
638025779	724	20.16	6	350	2	354	4.0e-20	93.7	COG0515	Serine/threonine protein kinase	384
638025780	419	39.61	7	417	6	382	6.0e-69	254	COG3268	Uncharacterized conserved protein, related to short-chain dehydrogenases	382
638025790	1109	29.61	271	650	73	449	9.0e-48	186	COG5002	Signal transduction histidine kinase	459
638025791	222	40.37	1	217	1	201	6.0e-47	180	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
638025794	311	30.8	79	309	3	265	4.0e-33	135	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
638025795	262	51.6	7	249	2	250	1.0e-81	296	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
638025796	432	65.19	1	428	1	423	0.0e+00	633	COG0148	Enolase	423
638025797	347	24.39	8	325	4	301	9.0e-21	94.6	COG1397	ADP-ribosylglycohydrolase	314
638025799	141	25.71	1	137	1	138	4.0e-10	57.5	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
638025800	321	60.54	1	319	1	329	3.0e-119	421	COG1494	Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase or related protein	332
638025801	142	41.22	1	130	5	132	2.0e-30	124	COG0824	Acyl-CoA thioesterase FadM	137
638025804	294	51.43	4	281	3	280	1.0e-82	299	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
638025805	1306	55.06	7	932	1	876	0.0e+00	1210	COG0525	Valyl-tRNA synthetase	877
638025808	457	42.22	258	436	1	178	4.0e-35	142	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638025810	517	24.09	1	265	68	334	9.0e-27	115	COG0642	Signal transduction histidine kinase	336
638025812	547	48.63	1	532	1	523	0.0e+00	499	COG0459	Chaperonin GroEL (HSP60 family)	524
638025814	372	20.99	13	252	19	250	2.0e-06	47.3	COG3063	Tfp pilus assembly protein PilF	250
638025814	372	30.51	254	370	16	132	6.0e-14	72.3	COG3824	Predicted Zn-dependent protease, minimal metalloprotease (MMP)-like domain	136
638025815	325	23.85	4	311	3	308	3.0e-22	99.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638025816	213	24.88	4	208	3	201	2.0e-10	59.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638025818	282	31.35	31	282	1	231	1.0e-19	90.4	COG2801	Transposase InsO and inactivated derivatives	232
638025819	1186	20.51	277	980	34	657	2.0e-31	132	COG1204	Replicative superfamily II helicase	766
638025823	388	25.76	40	387	2	336	5.0e-23	102	COG0515	Serine/threonine protein kinase	384
638025824	160	30.65	59	120	7	68	3.0e-07	47.9	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
638025826	650	25.17	17	293	1	289	1.0e-32	135	COG0515	Serine/threonine protein kinase	384
638025835	344	37.95	9	202	41	233	6.0e-24	104	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
638025844	358	21.36	66	351	55	339	1.0e-11	64.2	COG3500	Phage protein D	350
638025847	133	36.17	32	125	19	109	3.0e-11	61.1	COG3628	Phage baseplate assembly protein W	116
638025855	235	23.83	5	230	2	218	2.0e-20	93.1	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
638025856	915	19.61	1	719	1	762	1.0e-13	72.8	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
638025857	375	21.61	2	369	1	387	1.0e-18	87.9	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
638025866	418	16.98	20	417	5	409	5.0e-08	52.7	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
638025868	1515	40.73	1149	1509	1	382	6.0e-81	296	COG3320	Thioester reductase domain of alpha aminoadipate reductase Lys2 and NRPSs	382
638025868	1515	44.66	302	949	1	642	0.0e+00	484	COG1020	Non-ribosomal peptide synthetase component F	642
638025869	2146	29.73	1473	1752	16	309	6.0e-31	131	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
638025869	2146	30.51	1769	1941	7	182	1.0e-11	67.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638025869	2146	45.49	33	1124	1	1052	0.0e+00	900	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638025870	5182	48.97	3361	4331	1	958	0.0e+00	880	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638025871	1857	45.09	34	1089	1	1034	0.0e+00	864	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638025872	1862	46.55	33	983	1	941	0.0e+00	842	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638025873	2417	49.53	165	1013	4	853	0.0e+00	749	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
638025875	2154	28.4	1428	1751	16	336	6.0e-33	138	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
638025875	2154	30.63	6	583	4	534	6.0e-84	307	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
638025877	405	22.73	206	362	4	192	2.0e-08	53.9	COG3179	Predicted chitinase	206
638025886	178	37.95	5	169	24	189	1.0e-37	148	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
638025887	489	21.02	8	453	9	490	1.0e-30	128	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
638025890	183	25.52	1	181	11	182	2.0e-13	68.8	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
638025893	369	30.26	1	360	1	380	3.0e-34	139	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
638025900	1056	28.42	396	667	3	279	6.0e-39	156	COG0515	Serine/threonine protein kinase	384
638025902	917	21.33	248	896	3	669	4.0e-37	150	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
638025904	838	31	257	451	28	224	1.0e-07	52.7	COG3063	Tfp pilus assembly protein PilF	250
638025906	405	24	35	244	2	225	4.0e-08	53.1	COG1994	Zn-dependent protease (includes SpoIVFB)	230
638025907	336	28.24	5	334	12	344	3.0e-54	205	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
638025908	352	38.87	1	348	1	322	1.0e-84	307	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
638025909	165	20.98	20	153	1	123	1.0e-06	46	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
638025912	367	21.26	178	367	9	214	1.0e-11	64.6	COG2755	Lysophospholipase L1 or related esterase	216
638025914	889	41.55	5	889	3	910	0.0e+00	717	COG2352	Phosphoenolpyruvate carboxylase	910
638025916	849	25.17	35	746	113	938	4.0e-83	303	COG4581	Superfamily II RNA helicase	1041
638025919	916	46.13	28	657	1	598	0.0e+00	548	COG1042	Acyl-CoA synthetase (NDP forming)	598
638025923	457	49.23	1	448	1	450	0.0e+00	480	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638025924	171	32.22	2	170	9	188	1.0e-26	113	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
638025926	288	23.55	4	277	11	282	5.0e-17	82.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638025927	283	26.79	43	236	36	239	3.0e-10	59.2	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
638025928	389	48.47	5	363	1	357	1.0e-118	420	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
638025929	532	37.45	1	526	3	529	0.0e+00	522	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
638025931	359	30.1	9	287	15	303	2.0e-42	166	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
638025934	552	34.93	10	282	2	287	1.0e-45	178	COG0515	Serine/threonine protein kinase	384
638025935	2091	38.15	1706	2049	1	339	3.0e-72	268	COG3320	Thioester reductase domain of alpha aminoadipate reductase Lys2 and NRPSs	382
638025935	2091	40.18	853	1502	1	642	6.0e-123	437	COG1020	Non-ribosomal peptide synthetase component F	642
638025936	456	26.25	24	430	9	413	1.0e-48	188	COG0112	Glycine/serine hydroxymethyltransferase	413
638025938	1095	37.85	232	899	1	642	9.0e-124	438	COG1020	Non-ribosomal peptide synthetase component F	642
638025939	2048	41.78	300	955	1	642	0.0e+00	482	COG1020	Non-ribosomal peptide synthetase component F	642
638025940	559	22.96	54	475	4	443	5.0e-35	142	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
638025941	1515	38.58	235	883	4	642	3.0e-106	381	COG1020	Non-ribosomal peptide synthetase component F	642
638025943	675	21.23	71	535	4	485	2.0e-26	114	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
638025944	3292	31.86	4	574	3	534	2.0e-81	299	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
638025944	3292	42.3	1984	2635	1	642	9.0e-128	453	COG1020	Non-ribosomal peptide synthetase component F	642
638025950	149	28.39	1	147	2	148	3.0e-14	71.6	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
638025952	477	19.18	10	426	1	359	1.0e-13	71.8	COG2814	Predicted arabinose efflux permease, MFS family	394
638025953	183	56.32	1	174	1	173	2.0e-61	228	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
638025954	295	58.48	3	291	1	286	6.0e-117	413	COG1209	dTDP-glucose pyrophosphorylase	286
638025955	300	34.25	1	290	1	276	1.0e-55	210	COG1091	dTDP-4-dehydrorhamnose reductase	281
638025956	341	59.12	1	334	1	340	0.0e+00	508	COG1088	dTDP-D-glucose 4,6-dehydratase	340
638025957	546	23.68	3	368	7	380	5.0e-23	102	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638025959	750	25.06	35	422	11	381	7.0e-27	116	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638025962	780	20.65	412	651	2	243	2.0e-14	75.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
638025964	1275	26.22	572	834	1	261	7.0e-24	107	COG1216	Glycosyltransferase, GT2 family	305
638025965	437	50.2	5	249	1	240	2.0e-82	299	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
638025966	260	33.33	1	258	6	261	1.0e-40	159	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
638025969	201	36.13	5	192	12	192	9.0e-21	93.5	COG0558	Phosphatidylglycerophosphate synthase	192
638025970	498	23.91	316	496	29	202	6.0e-10	59.1	COG2013	Uncharacterized conserved protein, AIM24 family	227
638025972	529	50.38	1	528	4	512	0.0e+00	607	COG0029	Aspartate oxidase	518
638025973	217	30.14	7	197	15	221	2.0e-09	56.3	COG0705	Membrane associated serine protease, rhomboid family	228
638025974	197	42.16	1	181	12	195	1.0e-41	163	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
638025976	188	38.67	8	187	2	176	4.0e-31	127	COG0461	Orotate phosphoribosyltransferase	201
638025977	489	26.02	290	478	2	192	8.0e-07	49.1	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
638025981	279	36.43	1	279	6	295	1.0e-45	176	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
638025982	624	27.59	93	293	39	241	4.0e-08	53.4	COG3063	Tfp pilus assembly protein PilF	250
638025983	836	32.24	566	747	1	173	7.0e-22	99.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638025985	246	55.97	4	246	1	243	6.0e-82	297	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
638025986	583	44.13	1	583	1	627	0.0e+00	626	COG1154	Deoxyxylulose-5-phosphate synthase	627
638025987	297	38.18	5	297	2	322	6.0e-60	224	COG0142	Geranylgeranyl pyrophosphate synthase	322
638025989	118	42.62	24	84	12	72	6.0e-08	49.6	COG1722	Exonuclease VII small subunit	81
638025990	500	41.56	2	474	5	425	1.0e-105	376	COG1570	Exonuclease VII, large subunit	440
638025994	281	29.69	53	281	81	309	3.0e-40	159	COG4965	Flp pilus assembly protein TadB	309
638025995	271	25.98	8	270	6	268	1.0e-17	83.5	COG3745	Flp pilus assembly protein CpaB	276
638026005	223	36.27	20	212	1	182	3.0e-30	125	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638026007	350	62.09	3	308	1	302	0.0e+00	460	COG4608	ABC-type oligopeptide transport system, ATPase component	309
638026008	327	54.15	1	324	1	316	8.0e-125	440	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
638026012	240	32.86	6	214	12	213	1.0e-26	113	COG0811	Biopolymer transport protein ExbB/TolQ	216
638026013	150	37.68	12	149	7	135	1.0e-22	98.7	COG0848	Biopolymer transport protein ExbD	137
638026014	614	30.73	39	470	6	392	6.0e-67	248	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638026015	221	28.86	1	144	9	157	3.0e-16	79	COG2030	Acyl dehydratase	159
638026016	149	22.83	21	146	37	158	1.0e-09	55.9	COG2030	Acyl dehydratase	159
638026017	325	25.58	1	322	3	339	4.0e-36	145	COG3804	Uncharacterized protein	350
638026018	371	35.04	3	342	16	357	3.0e-64	239	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
638026019	148	48.2	9	142	2	140	2.0e-41	161	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
638026021	311	47.66	1	311	9	329	7.0e-69	254	COG0714	MoxR-like ATPase	329
638026022	445	32.87	11	441	4	416	4.0e-45	176	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
638026025	351	24.4	49	334	1	244	2.0e-24	106	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
638026026	308	32.14	1	307	3	294	9.0e-42	164	COG1597	Diacylglycerol kinase family enzyme	301
638026027	606	52.53	10	601	1	584	0.0e+00	794	COG0173	Aspartyl-tRNA synthetase	585
638026030	75	34.88	11	53	4	46	6.0e-08	49.2	COG3350	Uncharacterized conserved protein, YHS domain	53
638026031	573	42.44	50	549	8	491	4.0e-110	392	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
638026033	392	42.75	129	383	51	305	3.0e-64	239	COG0341	Preprotein translocase subunit SecF	305
638026034	590	41.2	58	590	36	506	8.0e-105	374	COG0342	Preprotein translocase subunit SecD	506
638026035	118	45.98	9	95	1	87	6.0e-21	93	COG1862	Preprotein translocase subunit YajC	97
638026036	378	59.07	4	366	1	361	0.0e+00	492	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
638026037	371	52.38	13	369	2	342	2.0e-127	449	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
638026041	410	49.86	24	389	3	369	6.0e-118	417	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
638026042	456	31.55	38	390	5	329	2.0e-62	233	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
638026043	941	27.42	9	299	1	295	6.0e-38	153	COG0515	Serine/threonine protein kinase	384
638026048	209	51.58	7	196	1	188	3.0e-62	231	COG0194	Guanylate kinase	191
638026049	292	38.01	1	292	1	290	1.0e-64	239	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
638026050	323	29.14	1	295	4	298	4.0e-31	129	COG0859	ADP-heptose:LPS heptosyltransferase	334
638026051	55	39.13	4	49	8	53	7.0e-06	42.1	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
638026054	397	35.04	10	379	5	315	9.0e-54	204	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
638026055	342	21.36	1	296	3	316	4.0e-14	72.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638026056	335	22.92	3	335	52	380	2.0e-25	110	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638026057	427	39.39	1	415	1	415	7.0e-89	321	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
638026058	382	24.77	43	235	1	214	2.0e-12	67	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
638026059	594	38.47	2	587	1	567	8.0e-118	417	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
638026061	383	45.79	4	379	1	380	5.0e-108	384	COG0763	Lipid A disaccharide synthetase	381
638026063	208	40.78	3	208	2	201	5.0e-35	141	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
638026066	268	37.59	3	267	6	276	3.0e-48	185	COG3494	Uncharacterized conserved protein, DUF1009 family	279
638026067	258	55.04	1	258	3	260	3.0e-94	338	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
638026068	153	58.22	1	144	4	147	3.0e-47	180	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
638026069	354	42.18	10	345	6	338	5.0e-83	301	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
638026070	187	27.38	10	175	5	170	1.0e-09	56.9	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
638026071	746	31.97	3	746	28	766	0.0e+00	483	COG4775	Outer membrane protein assembly factor BamA	766
638026072	224	45.5	3	223	1	222	1.0e-72	266	COG1136	ABC-type lipoprotein export system, ATPase component	226
638026073	789	33.25	371	789	25	408	9.0e-76	278	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
638026074	517	56.14	20	514	9	500	0.0e+00	667	COG1190	Lysyl-tRNA synthetase (class II)	502
638026076	208	42.08	25	207	2	179	3.0e-29	121	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638026077	373	57.02	126	360	1	235	9.0e-89	320	COG1186	Protein chain release factor B	239
638026079	294	42.76	134	275	2	145	2.0e-37	150	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
638026080	837	29.31	33	803	15	693	6.0e-114	405	COG1480	Membrane-associated HD superfamily phosphohydrolase	700
638026081	361	52.96	11	325	10	330	1.0e-98	353	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
638026088	831	49.28	1	830	1	814	0.0e+00	951	COG0495	Leucyl-tRNA synthetase	814
638026089	956	15.29	83	748	53	639	8.0e-12	66.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
638026091	296	44.44	1	287	1	286	3.0e-64	238	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
638026093	249	45.23	1	237	1	241	8.0e-63	233	COG1131	ABC-type multidrug transport system, ATPase component	293
638026095	345	45.09	7	345	2	347	8.0e-86	310	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
638026096	290	38.89	14	281	2	265	7.0e-62	230	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
638026097	659	31.69	300	566	20	303	9.0e-13	69.2	COG1413	HEAT repeat	335
638026099	174	39.31	17	161	8	152	2.0e-28	118	COG0835	Chemotaxis signal transduction protein	165
638026100	188	34.48	43	187	19	153	1.0e-23	102	COG0835	Chemotaxis signal transduction protein	165
638026101	862	37.21	218	852	98	707	2.0e-122	433	COG0643	Chemotaxis protein histidine kinase CheA	716
638026104	140	41.18	1	134	7	142	6.0e-33	133	COG0781	Transcription termination factor NusB	151
638026105	167	52.6	5	158	4	152	2.0e-43	168	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
638026106	220	52.68	1	204	1	204	3.0e-67	248	COG0307	Riboflavin synthase alpha chain	204
638026107	387	48.15	169	383	1	212	5.0e-50	192	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
638026107	387	57.86	29	168	7	146	5.0e-53	202	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
638026108	168	58.97	1	156	1	156	6.0e-53	200	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
638026109	418	64.25	1	413	1	412	0.0e+00	636	COG0112	Glycine/serine hydroxymethyltransferase	413
638026110	147	53.38	1	146	1	148	2.0e-43	168	COG0698	Ribose 5-phosphate isomerase RpiB	151
638026111	417	58.13	2	417	1	411	0.0e+00	492	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
638026112	80	63.75	1	80	1	80	1.0e-12	64.6	COG0236	Acyl carrier protein	80
638026113	249	49.8	4	247	3	250	3.0e-54	205	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638026114	313	58.71	1	308	1	310	2.0e-96	345	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
638026115	353	46.83	1	328	2	329	4.0e-102	365	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
638026116	62	48.28	1	58	1	56	6.0e-09	52.2	COG0333	Ribosomal protein L32	57
638026117	200	26	50	199	50	176	2.0e-14	72.7	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
638026120	226	48.03	3	226	2	228	3.0e-54	205	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638026121	454	34.41	83	444	83	447	5.0e-62	232	COG5002	Signal transduction histidine kinase	459
638026122	316	19.9	2	197	1	152	4.0e-07	49.2	COG0622	Predicted phosphodiesterase	172
638026123	164	34.16	8	158	4	163	1.0e-12	66.1	COG2062	Phosphohistidine phosphatase SixA	163
638026124	150	32.8	27	147	1	122	7.0e-11	59.9	COG4272	Uncharacterized membrane protein	125
638026125	280	32.5	1	279	1	256	6.0e-14	71.6	COG0730	Uncharacterized membrane protein YfcA	258
638026126	246	30.99	1	210	4	207	3.0e-38	152	COG0288	Carbonic anhydrase	207
638026127	515	34.01	20	478	24	509	3.0e-73	269	COG0659	Sulfate permease or related transporter, MFS superfamily	554
638026128	447	42.7	1	446	3	453	2.0e-112	399	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638026129	549	23.76	256	549	41	333	7.0e-24	105	COG0642	Signal transduction histidine kinase	336
638026130	229	49.78	2	227	1	229	1.0e-56	212	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638026131	273	36.69	17	272	37	313	2.0e-45	176	COG0226	ABC-type phosphate transport system, periplasmic component	318
638026132	332	42.33	25	316	12	299	2.0e-60	226	COG0573	ABC-type phosphate transport system, permease component	310
638026133	303	45	2	298	8	291	1.0e-56	213	COG0581	ABC-type phosphate transport system, permease component	292
638026134	247	72.87	1	247	8	253	3.0e-125	441	COG1117	ABC-type phosphate transport system, ATPase component	253
638026135	228	40.37	4	220	7	224	3.0e-39	155	COG0704	Phosphate uptake regulator	240
638026136	402	21.32	1	371	9	382	1.0e-21	97.7	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
638026138	427	39.34	2	426	13	429	2.0e-90	326	COG1253	Hemolysin or related protein, contains CBS domains	429
638026143	754	43.06	1	550	1	545	0.0e+00	537	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
638026144	205	23.85	9	138	3	130	1.0e-14	73.4	COG3521	Predicted component of the type VI protein secretion system	159
638026145	455	33.86	1	439	1	435	2.0e-73	270	COG3522	Predicted component of the type VI protein secretion system	446
638026146	238	30.23	6	216	43	255	3.0e-24	105	COG3455	Type VI protein secretion system component VasF	262
638026147	1231	27.95	5	1206	23	1184	0.0e+00	527	COG3523	Type VI protein secretion system component VasK	1188
638026150	164	42.59	2	161	5	165	2.0e-38	152	COG3516	Predicted component of the type VI protein secretion system	169
638026151	494	51.81	1	494	2	493	0.0e+00	658	COG3517	Predicted component of the type VI protein secretion system	495
638026152	163	26.22	1	160	1	155	6.0e-19	87.3	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
638026153	131	28.87	3	127	8	149	1.0e-14	72.3	COG3518	Predicted component of the type VI protein secretion system	157
638026154	583	37	2	583	5	621	6.0e-111	395	COG3519	Type VI protein secretion system component VasA	621
638026155	323	32.92	2	316	23	324	7.0e-45	174	COG3520	Predicted component of the type VI protein secretion system	335
638026156	885	40.92	15	877	1	777	0.0e+00	753	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
638026159	185	25.71	49	169	2	135	4.0e-12	64.9	COG1225	Peroxiredoxin	157
638026160	455	20.85	28	348	16	321	1.0e-21	98.2	COG2273	Beta-glucanase, GH16 family	355
638026161	355	48.74	1	352	1	345	2.0e-94	339	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
638026162	275	67.29	7	272	12	277	1.0e-99	356	COG4208	ABC-type sulfate transport system, permease component	287
638026163	280	55.97	6	273	5	272	1.0e-71	263	COG0555	ABC-type sulfate transport system, permease component	274
638026164	336	66.47	3	333	17	346	0.0e+00	504	COG1613	ABC-type sulfate transport system, periplasmic component	348
638026166	1149	30.45	228	825	133	785	4.0e-93	336	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
638026167	1127	31.92	216	793	153	785	8.0e-96	346	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
638026168	836	30.9	248	827	136	777	4.0e-90	326	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
638026169	193	56.78	1	192	2	199	6.0e-72	263	COG0605	Superoxide dismutase	204
638026170	166	28.75	10	158	5	164	3.0e-20	91.6	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
638026172	753	25.61	46	752	31	725	3.0e-70	260	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
638026173	153	50.97	1	153	2	156	8.0e-56	209	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
638026175	884	55.16	83	870	2	786	0.0e+00	933	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
638026179	487	19.95	1	405	6	359	1.0e-11	64.8	COG2814	Predicted arabinose efflux permease, MFS family	394
638026181	557	37.29	92	550	8	473	4.0e-96	345	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
638026183	302	40.49	18	297	1	273	7.0e-58	217	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
638026184	404	24.61	42	354	1	277	4.0e-17	82.9	COG0515	Serine/threonine protein kinase	384
638026185	596	26.13	16	304	1	298	2.0e-30	127	COG0515	Serine/threonine protein kinase	384
638026194	334	27.8	52	310	34	294	2.0e-19	90.7	COG4974	Site-specific recombinase XerD	300
638026196	548	48.25	1	453	1	445	0.0e+00	480	COG0541	Signal recognition particle GTPase	451
638026210	478	19.8	147	424	54	337	4.0e-08	53	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
638026214	108	47.12	2	105	1	104	9.0e-30	121	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
638026216	868	23.91	575	830	20	299	4.0e-08	54.1	COG3391	DNA-binding beta-propeller fold protein YncE	381
638026217	397	33.78	1	397	1	447	1.0e-77	283	COG0527	Aspartokinase	447
638026218	240	45.68	1	240	4	246	1.0e-67	249	COG1131	ABC-type multidrug transport system, ATPase component	293
638026219	267	21.43	1	210	1	196	1.0e-07	50.5	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
638026220	523	19	10	521	19	536	1.0e-07	51.5	COG3225	ABC-type uncharacterized transport system involved in gliding motility, auxiliary component	538
638026222	234	24.89	2	234	7	214	1.0e-10	60.7	COG2129	Predicted phosphoesterase, related to the Icc protein	226
638026228	545	62.76	24	542	1	520	0.0e+00	692	COG0033	Phosphoglucomutase	524
638026230	78	47.06	1	66	1	68	2.0e-11	60.3	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
638026234	96	62.5	1	96	1	96	8.0e-30	121	COG0234	Co-chaperonin GroES (HSP10)	96
638026235	549	49.54	1	532	2	524	0.0e+00	497	COG0459	Chaperonin GroEL (HSP60 family)	524
638026236	85	51.25	2	80	1	80	2.0e-20	90.8	COG0695	Glutaredoxin	80
638026239	459	27.01	7	142	51	186	2.0e-10	60.7	COG1716	Forkhead associated (FHA) domain, binds pSer, pThr, pTyr	191
638026239	459	40.72	128	454	135	464	1.0e-76	281	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638026241	1200	34.96	1	1189	1	1159	0.0e+00	626	COG1196	Chromosome segregation ATPase	1163
638026243	463	38.37	3	442	2	428	2.0e-98	353	COG1253	Hemolysin or related protein, contains CBS domains	429
638026244	271	29.69	17	204	41	230	5.0e-14	71.9	COG3063	Tfp pilus assembly protein PilF	250
638026245	405	31.63	93	379	68	356	8.0e-35	141	COG2843	Poly-gamma-glutamate biosynthesis protein CapA/YwtB (capsule formation), metallophosphatase superfamily	372
638026247	362	53.24	1	352	5	359	0.0e+00	466	COG0216	Protein chain release factor A	363
638026248	293	47.84	7	283	2	274	3.0e-68	251	COG2890	Methylase of polypeptide chain release factors	280
638026249	420	62.56	1	420	1	420	0.0e+00	587	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
638026256	139	32.97	1	85	1	91	2.0e-09	55.1	COG3293	Transposase	124
638026259	421	36.21	13	414	21	410	7.0e-68	251	COG2124	Cytochrome P450	411
638026265	385	28.9	149	343	46	254	9.0e-21	95.1	COG2890	Methylase of polypeptide chain release factors	280
638026270	469	30.17	4	460	9	450	2.0e-49	190	COG1231	Monoamine oxidase	450
638026275	401	25	138	401	41	315	4.0e-26	112	COG0627	S-formylglutathione hydrolase FrmB	316
638026282	584	21.16	1	573	1	542	9.0e-34	138	COG2303	Choline dehydrogenase or related flavoprotein	542
638026285	345	40.2	22	317	1	291	1.0e-61	230	COG1533	DNA repair photolyase	297
638026286	82	46.34	1	82	1	81	2.0e-06	43.9	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
638026288	362	46.98	1	362	4	365	3.0e-116	411	COG1932	Phosphoserine aminotransferase	365
638026289	212	34.09	32	205	6	178	7.0e-18	84	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638026295	281	46.18	10	280	1	274	9.0e-77	280	COG3220	Uncharacterized conserved protein, UPF0276 family	282
638026298	539	38.58	159	480	3	321	3.0e-73	269	COG3800	Predicted transcriptional regulator	332
638026301	260	38.25	1	250	5	254	2.0e-17	83.1	COG0730	Uncharacterized membrane protein YfcA	258
638026303	531	46.31	18	504	13	484	0.0e+00	463	COG0260	Leucyl aminopeptidase	485
638026306	361	29.46	143	356	23	243	4.0e-27	116	COG1651	Protein-disulfide isomerase	244
638026307	314	65.14	8	288	4	287	7.0e-115	407	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
638026309	343	63.19	10	335	5	330	0.0e+00	495	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
638026312	202	41.09	1	199	1	201	3.0e-44	171	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
638026313	191	46.3	4	165	1	160	7.0e-38	150	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
638026314	249	52.48	1	241	1	241	1.0e-84	306	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
638026317	458	44.52	1	458	1	457	7.0e-117	414	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638026321	338	45.88	1	337	2	341	2.0e-86	312	COG0430	RNA 3'-terminal phosphate cyclase	341
638026322	411	36.7	17	411	6	432	4.0e-103	368	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
638026323	540	60.22	7	540	2	530	0.0e+00	669	COG4650	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain	531
638026324	472	19.19	91	431	59	369	5.0e-11	62.8	COG0006	Xaa-Pro aminopeptidase	384
638026327	200	35.33	23	188	15	175	1.0e-17	83.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638026328	535	27.38	188	529	2	334	4.0e-31	129	COG0642	Signal transduction histidine kinase	336
638026329	290	26.15	4	278	3	277	2.0e-18	86.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638026330	188	23.12	1	160	6	165	3.0e-07	48.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638026331	252	28.1	8	251	12	282	1.0e-16	80.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638026332	243	31.93	1	238	4	231	9.0e-30	123	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
638026333	298	24.46	64	292	67	292	4.0e-08	52.6	COG5006	Threonine/homoserine efflux transporter RhtA	292
638026335	194	27.6	12	194	29	220	4.0e-24	104	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
638026338	142	54.14	5	137	6	137	5.0e-34	136	COG3011	Predicted thiol-disulfide oxidoreductase YuxK, DCC family	137
638026339	506	33.86	66	499	163	568	1.0e-62	234	COG4232	Thiol:disulfide interchange protein	569
638026341	458	51.48	8	442	1	386	0.0e+00	515	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
638026342	133	51.72	1	126	5	146	1.0e-36	145	COG0822	NifU homolog involved in Fe-S cluster formation	150
638026343	113	52.73	4	113	1	110	2.0e-36	143	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
638026344	195	37.76	13	146	2	141	5.0e-12	64.6	COG1076	DnaJ-domain-containing proteins 1	174
638026345	615	44.35	19	601	7	579	0.0e+00	506	COG0443	Molecular chaperone DnaK (HSP70)	579
638026346	125	38.24	1	99	1	100	3.0e-11	60.8	COG0633	Ferredoxin	102
638026356	154	31.85	4	151	13	164	1.0e-17	82.8	COG4304	Uncharacterized protein	166
638026357	359	25.45	6	329	4	296	5.0e-26	112	COG1577	Mevalonate kinase	307
638026358	332	40.31	6	325	5	324	1.0e-72	266	COG3407	Mevalonate pyrophosphate decarboxylase	329
638026359	310	34.04	8	282	1	279	3.0e-49	188	COG1577	Mevalonate kinase	307
638026360	442	34.02	2	429	9	434	6.0e-94	338	COG1257	Hydroxymethylglutaryl-CoA reductase	436
638026361	352	36.09	6	351	10	360	3.0e-62	232	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
638026362	128	20	1	106	5	114	6.0e-06	43.3	COG2210	Peroxiredoxin family protein	137
638026363	802	22.38	105	801	37	752	2.0e-72	267	COG4772	Outer membrane receptor for Fe3+-dicitrate	753
638026365	438	19.71	90	429	39	351	2.0e-11	64.3	COG3489	Predicted periplasmic lipoprotein	359
638026367	300	39.25	1	282	23	296	2.0e-41	163	COG0501	Zn-dependent protease with chaperone function	302
638026370	462	23.18	8	454	1	439	8.0e-23	102	COG1538	Outer membrane protein TolC	457
638026371	377	30.75	1	351	14	370	7.0e-21	95.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
638026372	1048	49.42	1	1027	1	1009	0.0e+00	990	COG0841	Multidrug efflux pump subunit AcrB	1009
638026375	443	33.41	5	418	17	438	1.0e-66	247	COG0612	Predicted Zn-dependent peptidase	438
638026376	441	23.5	206	413	35	243	6.0e-06	45.7	COG3063	Tfp pilus assembly protein PilF	250
638026379	145	61.82	20	129	5	114	1.0e-40	158	COG3564	Uncharacterized conserved protein, DUF779 family	116
638026380	506	44.56	19	501	1	472	0.0e+00	509	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638026381	737	35.18	54	731	12	604	2.0e-95	344	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
638026385	1223	31.36	111	371	2	282	8.0e-39	156	COG0515	Serine/threonine protein kinase	384
638026388	529	36.71	113	477	107	453	4.0e-73	269	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638026394	283	39.35	6	277	2	270	9.0e-66	243	COG0253	Diaminopimelate epimerase	272
638026395	2014	19.58	549	1389	173	1013	2.0e-20	96.6	COG1196	Chromosome segregation ATPase	1163
638026397	785	35.75	37	749	1	693	0.0e+00	576	COG0209	Ribonucleotide reductase alpha subunit	696
638026398	349	32.4	24	342	29	343	1.0e-67	250	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
638026403	336	35.22	4	311	3	318	1.0e-53	203	COG5351	Uncharacterized protein	367
638026407	211	45.41	4	209	2	207	8.0e-33	133	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
638026408	278	35.39	18	246	1	241	3.0e-44	171	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
638026409	177	50.6	10	177	10	177	5.0e-57	213	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
638026410	271	27.76	24	267	4	207	4.0e-17	82.1	COG0035	Uracil phosphoribosyltransferase	210
638026411	199	41.79	6	194	1	201	1.0e-58	219	COG1435	Thymidine kinase	201
638026413	99	51.22	1	81	1	82	3.0e-24	103	COG2088	DNA-binding protein SpoVG, cell septation regulator	95
638026414	316	58.15	4	315	3	313	6.0e-120	423	COG0462	Phosphoribosylpyrophosphate synthetase	314
638026415	220	42.11	5	99	1	93	4.0e-18	84.9	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
638026416	191	50.52	1	191	2	190	4.0e-65	240	COG0193	Peptidyl-tRNA hydrolase	190
638026417	158	32.69	11	114	1	103	2.0e-14	72.2	COG0360	Ribosomal protein S6	112
638026418	131	59.7	58	124	9	75	8.0e-22	96.1	COG0238	Ribosomal protein S18	75
638026419	147	46.94	1	147	1	147	4.0e-36	144	COG0359	Ribosomal protein L9	148
638026422	256	36.11	6	255	4	244	9.0e-42	163	COG3279	DNA-binding response regulator, LytR/AlgR family	244
638026423	456	46.29	11	454	1	435	1.0e-124	440	COG0305	Replicative DNA helicase	435
638026424	246	37.2	1	244	2	246	1.0e-39	156	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
638026425	254	42.98	13	252	2	241	4.0e-62	231	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
638026426	218	41.71	6	215	1	210	3.0e-42	165	COG0352	Thiamine monophosphate synthase	211
638026431	874	57.91	5	861	1	783	0.0e+00	963	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
638026433	338	25.23	9	325	2	331	2.0e-43	170	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
638026434	461	43.67	37	461	26	481	4.0e-116	411	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
638026435	442	30.53	14	429	3	390	9.0e-49	188	COG2311	Uncharacterized membrane protein YeiB	394
638026436	437	44.74	33	436	7	391	1.0e-101	363	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
638026438	138	40.54	27	137	9	119	3.0e-27	114	COG1733	DNA-binding transcriptional regulator, HxlR family	120
638026439	287	34.53	3	272	1	275	5.0e-24	104	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
638026440	183	24.31	3	182	1	176	6.0e-06	43.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638026442	144	32.45	1	140	1	150	2.0e-20	91.4	COG1438	Arginine repressor	150
638026443	335	34.23	1	331	6	307	1.0e-64	240	COG0078	Ornithine carbamoyltransferase	310
638026444	308	44.2	22	297	1	265	2.0e-66	246	COG0548	Acetylglutamate kinase	265
638026445	353	28.5	1	349	13	409	9.0e-43	167	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
638026446	449	39.07	1	426	1	427	4.0e-98	351	COG0165	Argininosuccinate lyase	459
638026447	396	40.15	1	396	1	399	4.0e-98	351	COG0137	Argininosuccinate synthase	403
638026449	355	40.06	4	355	3	349	4.0e-86	311	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
638026450	266	27.48	11	229	7	223	3.0e-17	82.7	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
638026451	536	30.97	5	414	9	425	1.0e-54	207	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
638026452	302	34.46	9	146	2	149	1.0e-10	60.4	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
638026454	265	47.18	1	248	1	247	1.0e-80	293	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
638026455	408	23.69	15	396	1	378	9.0e-35	141	COG0515	Serine/threonine protein kinase	384
638026456	328	36.57	8	315	75	378	7.0e-62	230	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
638026457	441	28.9	3	422	2	421	2.0e-33	137	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
638026459	261	35.19	5	112	1	108	8.0e-19	87.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
638026462	341	24.07	23	339	9	327	3.0e-18	86.4	COG0642	Signal transduction histidine kinase	336
638026463	488	47.17	1	477	4	462	7.0e-128	451	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638026464	248	31.25	45	236	22	212	9.0e-29	120	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
638026466	525	28.57	12	287	24	259	3.0e-35	143	COG3186	Phenylalanine-4-hydroxylase	291
638026467	303	26.01	10	300	3	289	1.0e-15	77.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
638026468	662	23.79	103	635	62	586	6.0e-44	172	COG3083	Membrane-anchored periplasmic protein YejM, alkaline phosphatase superfamily	600
638026471	573	30.11	137	413	22	280	4.0e-10	60.3	COG1413	HEAT repeat	335
638026474	399	42.04	12	396	2	390	6.0e-89	321	COG0183	Acetyl-CoA acetyltransferase	392
638026475	792	26.7	491	694	20	204	4.0e-18	87.1	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638026475	792	32.91	3	318	1	298	3.0e-65	243	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
638026476	584	21.53	20	575	27	634	2.0e-59	223	COG0308	Aminopeptidase N	859
638026477	294	30.11	27	294	15	270	2.0e-46	179	COG0863	DNA modification methylase	302
638026478	73	45.33	1	71	1	75	4.0e-17	79.5	COG0254	Ribosomal protein L31	75
638026481	323	23.24	128	311	77	261	2.0e-16	80.4	COG1729	Periplasmic TolA-binding protein (function unknown)	262
638026482	440	36.19	10	268	7	268	1.0e-44	174	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
638026483	352	42.45	4	347	1	347	3.0e-78	285	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
638026485	798	29.66	5	662	7	714	4.0e-96	346	COG0643	Chemotaxis protein histidine kinase CheA	716
638026486	605	29.19	250	595	66	408	3.0e-41	163	COG0840	Methyl-accepting chemotaxis protein	408
638026487	595	27.72	204	589	30	408	2.0e-42	167	COG0840	Methyl-accepting chemotaxis protein	408
638026489	145	24.82	8	141	15	155	2.0e-15	75.3	COG0835	Chemotaxis signal transduction protein	165
638026491	498	47.7	1	497	3	462	0.0e+00	515	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638026493	470	23.54	79	461	21	399	2.0e-32	134	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
638026496	249	36.99	11	180	13	185	8.0e-23	100	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
638026498	129	35.88	5	129	12	141	2.0e-09	55	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
638026499	224	47.79	1	222	1	223	5.0e-58	217	COG2135	Putative SOS response-associated peptidase YedK	226
638026501	472	30.02	23	469	29	412	9.0e-63	234	COG0232	dGTP triphosphohydrolase	412
638026503	540	21.72	1	519	4	537	4.0e-38	152	COG2303	Choline dehydrogenase or related flavoprotein	542
638026505	585	41.46	11	584	1	567	4.0e-129	455	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
638026506	807	19.23	22	404	4	417	5.0e-18	87.1	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
638026509	325	18.92	13	319	6	331	1.0e-16	80.5	COG0859	ADP-heptose:LPS heptosyltransferase	334
638026510	501	22.12	98	421	15	324	8.0e-33	135	COG0641	Sulfatase maturation enzyme AslB, radical SAM superfamily	378
638026512	565	25.51	5	240	9	232	3.0e-14	73.7	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
638026514	846	30.11	40	295	2	277	1.0e-45	178	COG0515	Serine/threonine protein kinase	384
638026514	846	35.33	362	509	3	152	8.0e-22	99.6	COG5616	TolB amino-terminal domain (function unknown)	152
638026516	256	48.28	1	256	1	261	3.0e-90	324	COG0708	Exonuclease III	261
638026517	242	26.46	30	210	63	250	7.0e-07	47.7	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
638026523	274	25.28	8	247	10	273	1.0e-25	110	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
638026524	110	54.72	1	106	1	106	2.0e-21	94	COG2076	Multidrug transporter EmrE and related cation transporters	106
638026526	119	22.41	1	116	1	110	2.0e-08	51	COG1544	Ribosome-associated translation inhibitor RaiA	110
638026530	351	30.74	81	348	35	315	8.0e-11	61.5	COG1413	HEAT repeat	335
638026532	476	35.58	316	474	27	187	4.0e-28	119	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
638026533	344	34.73	14	342	19	397	2.0e-63	236	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
638026535	272	26.02	54	239	29	223	6.0e-18	84.9	COG1651	Protein-disulfide isomerase	244
638026536	353	34.31	1	327	19	351	4.0e-64	238	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
638026537	307	42.11	129	299	9	178	3.0e-39	156	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638026540	175	47.97	25	172	1	148	1.0e-33	136	COG1610	Uncharacterized conserved protein YqeY	148
638026541	606	30.22	5	582	2	567	1.0e-86	314	COG0358	DNA primase (bacterial type)	568
638026542	708	55.06	374	707	9	342	1.0e-88	321	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
638026543	147	42.7	39	125	6	92	2.0e-16	78.4	COG3695	Alkylated DNA nucleotide flippase Atl1, participates in nucleotide excision repair, Ada-like DNA-binding domain	103
638026545	453	33.33	2	401	1	366	1.0e-46	180	COG5659	SRSO17 transposase	385
638026546	248	41.9	4	247	1	251	2.0e-40	159	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638026547	105	45.71	1	105	2	106	1.0e-16	78.6	COG2076	Multidrug transporter EmrE and related cation transporters	106
638026548	194	22.92	1	191	6	191	5.0e-08	51.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638026549	490	35.05	177	478	26	332	8.0e-37	148	COG0642	Signal transduction histidine kinase	336
638026550	224	44.1	1	224	1	228	4.0e-47	181	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638026551	385	17.96	44	372	2	298	5.0e-13	69.3	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
638026553	436	28.52	17	303	31	326	4.0e-27	116	COG3344	Retron-type reverse transcriptase	328
638026557	596	30.36	353	594	12	246	1.0e-29	125	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
638026558	499	32.04	185	464	1	264	1.0e-34	141	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
638026560	270	26.1	1	247	1	234	3.0e-28	119	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
638026562	637	33.28	28	627	1	562	5.0e-92	332	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
638026567	476	38.63	13	471	5	407	2.0e-87	316	COG2262	50S ribosomal subunit-associated GTPase HflX	411
638026568	423	44.6	1	420	29	451	3.0e-103	369	COG0513	Superfamily II DNA and RNA helicase	513
638026570	303	35.36	40	293	31	288	5.0e-51	195	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
638026576	199	31.79	24	190	9	181	2.0e-25	108	COG2320	GrpB domain, predicted nucleotidyltransferase, UPF0157 family	185
638026582	202	46.24	5	190	3	182	7.0e-49	186	COG3059	Uncharacterized membrane protein YkgB	182
638026583	216	23.73	40	216	4	177	1.0e-10	60.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638026589	246	25.76	45	240	13	206	3.0e-16	78.8	COG0400	Predicted esterase	207
638026591	343	36.71	4	340	1	310	4.0e-67	248	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
638026601	189	26.47	6	171	12	181	1.0e-15	76.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638026602	315	49.66	9	300	2	292	2.0e-74	272	COG1230	Co/Zn/Cd efflux system component	296
638026605	414	18.31	49	389	66	423	1.0e-05	44.8	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
638026613	601	36.92	27	583	14	567	2.0e-115	410	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
638026614	586	37.39	1	566	3	565	4.0e-107	382	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
638026631	561	25.08	246	557	46	324	1.0e-17	85	COG5276	Uncharacterized conserved protein	370
638026636	711	26.27	110	709	2	619	4.0e-71	263	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
638026642	902	28.21	8	899	3	891	3.0e-108	386	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
638026643	182	37.04	6	163	2	160	1.0e-22	99.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638026647	66	64.18	1	66	1	67	9.0e-22	95.2	COG1278	Cold shock protein, CspA family	67
638026650	226	50.22	4	225	2	229	3.0e-59	221	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638026651	466	31.75	137	461	8	336	1.0e-34	141	COG0642	Signal transduction histidine kinase	336
638026653	274	30	57	274	71	283	1.0e-08	54.1	COG0842	ABC-type multidrug transport system, permease component	286
638026654	330	40.59	13	313	3	293	2.0e-67	249	COG1131	ABC-type multidrug transport system, ATPase component	293
638026655	294	42.91	1	294	7	301	2.0e-66	245	COG0109	Polyprenyltransferase (heme O synthase)	304
638026659	620	21.57	2	613	4	548	2.0e-41	164	COG0443	Molecular chaperone DnaK (HSP70)	579
638026660	925	22.28	1	595	5	554	6.0e-45	176	COG0443	Molecular chaperone DnaK (HSP70)	579
638026662	595	28.14	4	580	1	508	2.0e-62	233	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
638026663	416	26.42	9	341	15	360	2.0e-35	143	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)	364
638026664	324	59.48	3	320	2	343	0.0e+00	492	COG1089	GDP-D-mannose dehydratase	345
638026665	308	30.18	2	300	4	335	2.0e-47	183	COG1089	GDP-D-mannose dehydratase	345
638026667	173	38.27	5	163	12	162	6.0e-35	140	COG3236	Predicted NAD-dependent protein-ADP-ribosyltransferase YbiA, DUF1768 family	162
638026669	361	30.57	4	361	3	380	3.0e-35	142	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638026670	746	25.63	43	347	67	378	1.0e-24	108	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638026672	273	22.27	2	221	1	204	5.0e-12	65.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
638026675	165	30.32	1	153	2	154	7.0e-18	83.4	COG2062	Phosphohistidine phosphatase SixA	163
638026676	110	29.67	2	91	1	88	3.0e-10	57.2	COG1965	Iron-binding protein CyaY, frataxin homolog	106
638026677	546	25.77	381	539	29	181	2.0e-13	70.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638026678	185	49.73	1	185	3	187	6.0e-56	210	COG0233	Ribosome recycling factor	187
638026679	250	65.11	11	244	5	238	5.0e-91	327	COG0528	Uridylate kinase	238
638026681	312	63.87	7	244	4	240	4.0e-98	351	COG0052	Ribosomal protein S2	252
638026683	340	30.97	17	334	8	350	1.0e-36	147	COG2933	23S rRNA C2498 (ribose-2'-O)-methylase RlmM	358
638026686	265	42.8	13	264	6	252	2.0e-58	219	COG0631	Serine/threonine protein phosphatase PrpC	262
638026687	578	45.97	1	554	1	557	0.0e+00	496	COG0497	DNA repair ATPase RecN	557
638026689	184	48.47	11	173	2	164	4.0e-45	174	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
638026690	276	23.51	1	265	1	282	6.0e-07	48.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638026693	202	25.39	1	193	4	194	4.0e-07	48.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638026694	403	26.15	67	388	72	386	1.0e-09	57.9	COG2814	Predicted arabinose efflux permease, MFS family	394
638026695	166	48.73	1	158	1	158	5.0e-46	177	COG0669	Phosphopantetheine adenylyltransferase	159
638026696	248	21.51	3	242	2	273	3.0e-12	65.8	COG1234	Ribonuclease BN, tRNA processing enzyme	292
638026697	588	27.51	9	586	37	626	6.0e-76	278	COG0296	1,4-alpha-glucan branching enzyme	628
638026698	536	31.86	16	508	2	502	5.0e-71	262	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
638026699	258	30.61	11	255	1	223	2.0e-20	93.3	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
638026700	305	39.22	26	304	1	281	2.0e-62	233	COG0061	NAD kinase	281
638026701	485	46.45	7	471	5	464	0.0e+00	499	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638026705	282	31.75	7	278	4	257	4.0e-35	142	COG3394	Predicted glycoside hydrolase or deacetylase ChbG, UPF0249 family	257
638026708	746	44.12	14	216	7	206	1.0e-40	161	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638026708	746	44.76	347	628	1	285	4.0e-77	282	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
638026709	433	38.07	9	432	1	391	8.0e-71	261	COG0183	Acetyl-CoA acetyltransferase	392
638026710	348	52.45	1	341	6	352	8.0e-108	383	COG0407	Uroporphyrinogen-III decarboxylase	352
638026711	789	23.52	242	639	3	493	8.0e-37	149	COG0366	Glycosidase	505
638026713	813	35.48	55	766	26	670	3.0e-126	446	COG1523	Pullulanase/glycogen debranching enzyme	697
638026714	362	54.07	1	344	1	338	3.0e-125	441	COG3839	ABC-type sugar transport system, ATPase component	338
638026715	726	30.83	15	377	32	402	2.0e-58	220	COG2182	Maltose-binding periplasmic protein MalE	420
638026715	726	37.04	427	720	3	289	2.0e-59	224	COG1175	ABC-type sugar transport system, permease component	295
638026716	282	39.93	1	282	5	282	7.0e-67	247	COG3833	ABC-type maltose transport system, permease component	282
638026722	150	29.66	2	127	11	154	2.0e-09	55.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638026723	379	32.03	94	334	4	247	4.0e-37	149	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
638026726	377	19.27	39	352	2	314	7.0e-19	88.5	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638026734	287	30.4	18	283	16	281	9.0e-15	74.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638026739	468	17.75	1	396	1	350	2.0e-33	137	COG1858	Cytochrome c peroxidase	364
638026743	137	59.68	5	128	7	130	9.0e-42	162	COG5649	Uncharacterized protein	132
638026744	356	33.72	1	343	22	342	3.0e-63	235	COG3049	Penicillin V acylase or related amidase, Ntn superfamily	353
638026747	420	49.64	9	418	6	414	5.0e-104	371	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
638026748	125	27.35	6	122	9	118	1.0e-11	61.8	COG3795	Uncharacterized conserved protein	123
638026749	619	19.81	147	448	22	292	3.0e-09	57.2	COG0501	Zn-dependent protease with chaperone function	302
638026755	209	35.46	64	201	5	142	9.0e-16	77	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
638026756	788	33.49	370	788	25	408	4.0e-76	279	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
638026757	420	26.9	35	416	24	405	1.0e-37	151	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
638026758	153	41.67	6	112	9	116	5.0e-30	123	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
638026760	229	48.58	1	212	2	212	9.0e-53	200	COG1926	Predicted phosphoribosyltransferase	220
638026762	358	32.21	1	349	17	369	2.0e-55	209	COG2843	Poly-gamma-glutamate biosynthesis protein CapA/YwtB (capsule formation), metallophosphatase superfamily	372
638026763	497	50.11	41	497	2	432	0.0e+00	488	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
638026764	140	31.94	4	140	1	137	7.0e-13	66.5	COG1371	SHS2 domain protein implicated in nucleic acid metabolism	137
638026765	483	27.83	14	209	27	247	4.0e-14	73	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
638026765	483	39.8	360	456	12	109	1.0e-15	78	COG0607	Rhodanese-related sulfurtransferase	110
638026775	567	36.52	147	566	67	506	1.0e-85	311	COG3227	Zn-dependent metalloprotease	507
638026781	669	29.4	275	656	2	428	2.0e-49	190	COG5184	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	476
638026782	249	30.86	1	246	1	266	1.0e-41	163	COG1018	Ferredoxin-NADP reductase	266
638026793	692	30.1	27	688	1	648	2.0e-99	357	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
638026794	362	25.45	12	288	23	286	5.0e-28	119	COG3239	Fatty acid desaturase	343
638026796	358	36.83	11	315	23	337	6.0e-60	224	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
638026797	160	23.62	28	150	7	133	7.0e-14	70.3	COG0824	Acyl-CoA thioesterase FadM	137
638026802	298	24.27	1	286	1	297	1.0e-21	97	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638026804	208	25.6	4	206	1	205	7.0e-18	84.1	COG0625	Glutathione S-transferase	211
638026809	916	23.15	30	438	1	410	7.0e-38	153	COG0612	Predicted Zn-dependent peptidase	438
638026812	186	34.38	28	183	17	176	2.0e-24	105	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
638026813	311	25.72	1	304	1	297	5.0e-23	101	COG0583	DNA-binding transcriptional regulator, LysR family	297
638026816	578	33.44	262	578	25	332	8.0e-40	158	COG0642	Signal transduction histidine kinase	336
638026819	336	31.01	1	157	1	154	1.0e-11	64.3	COG1988	Membrane-bound metal-dependent hydrolase YbcI, DUF457 family	190
638026822	236	50.46	14	230	7	220	3.0e-64	238	COG0120	Ribose 5-phosphate isomerase	227
638026825	298	28.18	7	293	2	289	1.0e-20	93.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
638026827	360	21.27	142	359	52	240	4.0e-07	49.1	COG3591	V8-like Glu-specific endopeptidase	251
638026829	122	34.19	3	119	1	116	6.0e-30	122	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
638026833	294	27.78	42	290	76	323	6.0e-35	141	COG2845	Uncharacterized protein	354
638026835	254	53.31	1	242	2	237	3.0e-89	321	COG1126	ABC-type polar amino acid transport system, ATPase component	240
638026836	481	27.24	1	255	9	275	6.0e-32	132	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
638026836	481	48.57	274	481	12	221	8.0e-56	211	COG0765	ABC-type amino acid transport system, permease component	222
638026837	138	51.11	1	135	2	136	1.0e-25	109	COG2510	Uncharacterized membrane protein	140
638026839	197	30.43	8	190	2	181	2.0e-15	76.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638026848	309	25.5	8	303	20	291	2.0e-33	136	COG3016	Uncharacterized iron-regulated protein	295
638026849	306	38.64	3	294	1	289	2.0e-63	236	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
638026852	405	26.18	36	375	10	363	1.0e-25	111	COG1680	CubicO group peptidase, beta-lactamase class C family	390
638026855	319	31.11	10	315	31	335	8.0e-43	167	COG1075	Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold	336
638026856	350	27.94	77	341	16	282	6.0e-28	118	COG5380	Lipase chaperone LimK	283
638026857	132	38.17	1	128	1	129	4.0e-23	100	COG3791	Uncharacterized conserved protein	133
638026859	153	52.38	1	147	2	146	3.0e-45	174	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
638026860	159	42.64	27	145	11	136	1.0e-29	122	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
638026862	202	46.02	1	198	1	226	6.0e-71	260	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
638026864	197	28.57	2	147	3	148	2.0e-15	76.1	COG3945	Hemerythrin-like domain	189
638026865	457	37.7	24	445	7	413	2.0e-109	389	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
638026866	646	21.5	2	464	3	463	2.0e-16	81.2	COG3593	Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains	581
638026867	479	30.48	32	381	4	334	9.0e-46	178	COG0348	Polyferredoxin	386
638026868	176	30.23	36	162	10	131	3.0e-08	51.5	COG2010	Cytochrome c, mono- and diheme variants	150
638026870	793	43.84	549	763	1	217	3.0e-60	227	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
638026870	793	58.7	1	490	4	482	0.0e+00	626	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
638026872	842	29.21	90	816	4	702	2.0e-103	370	COG2217	Cation transport ATPase	713
638026873	237	33.52	24	191	7	183	1.0e-12	66.8	COG2836	Sulfite exporter TauE/SafE	232
638026874	241	21.78	29	228	2	201	3.0e-12	65.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638026875	186	33.33	5	181	51	223	5.0e-33	134	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
638026876	207	22.22	1	189	1	187	4.0e-08	51.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638026877	291	33.45	12	287	7	280	2.0e-43	169	COG4757	Predicted alpha/beta hydrolase	281
638026878	259	38.43	1	254	3	256	3.0e-42	165	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638026881	357	30.35	10	344	3	342	6.0e-43	168	COG0673	Predicted dehydrogenase	342
638026883	182	20.87	66	180	28	137	1.0e-06	46.5	COG2010	Cytochrome c, mono- and diheme variants	150
638026885	492	21.69	45	446	19	393	2.0e-18	87.7	COG5557	Ni/Fe-hydrogenase 2 integral membrane subunit HybB	401
638026886	992	28.07	755	980	6	191	2.0e-34	141	COG0437	Fe-S-cluster-containing dehydrogenase component	203
638026888	205	26.03	1	195	2	211	4.0e-07	48.3	COG2181	Nitrate reductase gamma subunit	228
638026891	369	40.54	9	353	4	362	8.0e-74	271	COG1858	Cytochrome c peroxidase	364
638026894	388	24.04	31	309	8	268	7.0e-06	45.3	COG3503	Uncharacterized membrane protein	323
638026895	192	34.04	1	140	1	141	6.0e-23	100	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
638026897	383	42.6	3	383	2	393	6.0e-86	311	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
638026899	371	48.94	4	328	1	329	2.0e-92	332	COG1929	Glycerate kinase	378
638026902	833	43.21	19	536	22	539	0.0e+00	479	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
638026904	481	24.39	4	394	13	354	2.0e-30	127	COG1488	Nicotinic acid phosphoribosyltransferase	405
638026906	245	35.23	12	204	1	171	2.0e-32	132	COG0221	Inorganic pyrophosphatase	171
638026907	245	34.15	40	241	36	234	3.0e-29	122	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
638026908	346	43.7	1	341	1	318	3.0e-88	318	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
638026911	349	21.64	14	347	13	338	2.0e-22	100	COG4260	Membrane protease subunit, stomatin/prohibitin family, contains C-terminal Zn-ribbon domain	345
638026913	305	38.03	1	302	2	293	3.0e-72	265	COG1131	ABC-type multidrug transport system, ATPase component	293
638026919	508	26.19	2	197	12	221	3.0e-17	83.6	COG0705	Membrane associated serine protease, rhomboid family	228
638026922	260	39.92	15	254	10	255	1.0e-36	146	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638026926	405	54.49	11	333	12	333	8.0e-98	350	COG0206	Cell division GTPase FtsZ	338
638026927	2699	29.25	2542	2688	44	189	3.0e-26	116	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
638026928	410	51.56	5	410	3	418	1.0e-122	433	COG0849	Cell division ATPase FtsA	418
638026929	299	22.34	30	297	10	267	2.0e-24	107	COG1589	Cell division septal protein FtsQ	269
638026930	318	43.13	14	311	1	313	2.0e-75	276	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
638026931	310	45.55	21	310	2	290	3.0e-76	278	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
638026932	472	53.2	17	465	9	458	0.0e+00	567	COG0773	UDP-N-acetylmuramate-alanine ligase	459
638026933	383	43.82	2	354	1	351	6.0e-95	341	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
638026934	388	41.71	13	370	13	372	4.0e-78	285	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
638026935	455	45.63	1	455	1	446	4.0e-113	401	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
638026936	392	37.2	28	392	5	316	6.0e-50	191	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
638026937	466	44.55	21	458	18	450	6.0e-106	378	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
638026938	507	43	23	504	9	475	9.0e-122	430	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
638026939	672	35.37	5	571	1	599	7.0e-121	428	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
638026941	304	52.26	6	304	5	313	1.0e-97	350	COG0275	16S rRNA C1402 N4-methylase RsmH	314
638026942	128	26.73	24	123	17	117	9.0e-08	49.2	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
638026943	150	44.7	1	132	1	131	6.0e-34	136	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
638026945	601	40.74	35	427	5	389	9.0e-77	281	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638026946	117	38.95	4	97	19	110	1.0e-09	55.2	COG0640	DNA-binding transcriptional regulator, ArsR family	110
638026947	219	22.73	25	140	7	138	5.0e-07	48.1	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
638026949	778	28.48	12	301	1	293	3.0e-38	154	COG0515	Serine/threonine protein kinase	384
638026951	316	32.08	12	170	7	165	1.0e-28	120	COG1329	RNA polymerase-interacting regulator, CarD/CdnL/TRCF family	166
638026952	170	23.64	13	165	18	176	4.0e-08	51.1	COG1913	Predicted Zn-dependent protease	181
638026954	616	18.33	73	487	58	442	5.0e-07	50.1	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
638026958	394	47.62	18	394	7	377	1.0e-111	396	COG1454	Alcohol dehydrogenase, class IV	377
638026959	449	36.9	2	448	4	443	1.0e-101	364	COG0174	Glutamine synthetase	443
638026960	251	36.61	26	207	14	189	6.0e-35	141	COG0518	GMP synthase - Glutamine amidotransferase domain	198
638026963	424	28.38	32	400	14	343	7.0e-36	145	COG0628	Predicted PurR-regulated permease PerM	355
638026965	420	67.77	1	420	1	420	0.0e+00	663	COG1158	Transcription termination factor Rho	422
638026966	672	54.46	1	668	1	666	0.0e+00	881	COG0272	NAD-dependent DNA ligase	667
638026967	99	48.86	8	95	3	90	1.0e-22	98	COG1254	Acylphosphatase	92
638026969	936	42.31	342	754	70	482	1.0e-98	354	COG1530	Ribonuclease G or E	487
638026970	461	26.35	44	306	21	296	3.0e-29	123	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
638026971	117	40.22	1	92	2	93	8.0e-22	95.6	COG0776	Bacterial nucleoid DNA-binding protein	94
638026972	688	41.93	4	681	2	686	0.0e+00	595	COG4789	Type III secretory pathway, component EscV	689
638026973	349	32.56	1	338	5	351	3.0e-68	252	COG1377	Flagellar biosynthesis protein FlhB	363
638026974	264	30.61	17	259	10	253	2.0e-19	89.9	COG4791	Type III secretory pathway, component EscT	259
638026975	89	46.43	1	84	1	84	4.0e-13	66.3	COG1987	Flagellar biosynthesis protein FliQ	89
638026976	218	45.33	5	218	2	213	1.0e-51	196	COG4790	Type III secretory pathway, component EscR	214
638026978	416	21.92	46	289	30	283	5.0e-11	62.6	COG1868	Flagellar motor switch protein FliM	332
638026980	267	31.09	1	235	1	234	5.0e-30	124	COG4669	Type III secretory pathway, lipoprotein EscJ	246
638026991	336	22.59	29	282	12	251	7.0e-07	48.4	COG1240	Mg-chelatase subunit ChlD	261
638026994	329	41.64	13	329	9	328	1.0e-67	250	COG0714	MoxR-like ATPase	329
638026995	296	30.26	40	293	19	282	2.0e-15	76.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638027000	537	39.02	113	527	148	559	2.0e-89	323	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
638027006	163	27.81	1	159	2	187	3.0e-22	98.1	COG4929	Uncharacterized membrane-anchored protein	190
638027007	246	29.58	20	231	3	205	2.0e-15	76.5	COG5398	Heme oxygenase	238
638027010	262	31.62	10	256	16	266	4.0e-13	68.8	COG0428	Zinc transporter ZupT	266
638027011	418	21.37	67	388	56	415	4.0e-24	105	COG3014	Uncharacterized protein	449
638027012	202	22.75	3	194	4	200	1.0e-11	63.1	COG3417	Outer membrane lipoprotein LpoB, binds and activates PBP1b	200
638027015	552	21.05	261	544	34	316	5.0e-22	99.6	COG0668	Small-conductance mechanosensitive channel	316
638027017	520	17.83	34	374	7	369	5.0e-09	56.3	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
638027018	676	25.89	562	673	1	110	1.0e-09	58.7	COG1388	LysM repeat	124
638027021	483	24.68	226	458	56	273	7.0e-26	112	COG1864	DNA/RNA endonuclease G, NUC1	281
638027024	840	22.45	15	378	1	368	2.0e-37	151	COG0515	Serine/threonine protein kinase	384
638027027	233	47.11	1	222	1	224	1.0e-69	256	COG1136	ABC-type lipoprotein export system, ATPase component	226
638027030	395	25.37	55	383	16	322	3.0e-14	72.9	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
638027031	245	24.41	1	213	3	211	5.0e-10	58.4	COG1842	Phage shock protein A	225
638027032	488	26.55	150	487	2	328	2.0e-33	137	COG0642	Signal transduction histidine kinase	336
638027033	448	39.81	1	418	1	413	6.0e-79	288	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
638027034	134	46.09	5	132	3	130	3.0e-36	143	COG0295	Cytidine deaminase	134
638027038	434	54.73	1	433	2	434	0.0e+00	535	COG0213	Thymidine phosphorylase	435
638027039	396	35.95	1	392	6	345	8.0e-62	231	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
638027040	485	52.4	2	478	28	501	0.0e+00	568	COG3845	ABC-type uncharacterized transport system, ATPase component	501
638027041	371	45.98	1	346	8	337	5.0e-60	225	COG4603	ABC-type uncharacterized transport system, permease component	356
638027042	309	44.66	1	307	3	303	3.0e-59	222	COG1079	ABC-type uncharacterized transport system, permease component	304
638027043	399	26.64	130	398	74	333	7.0e-23	101	COG0642	Signal transduction histidine kinase	336
638027045	575	32.06	40	538	2	442	9.0e-85	308	COG1109	Phosphomannomutase	464
638027046	130	27.03	1	111	1	108	1.0e-10	58.9	COG1734	RNA polymerase-binding transcription factor DksA	120
638027047	227	57.6	9	223	7	223	2.0e-67	248	COG0274	Deoxyribose-phosphate aldolase	228
638027048	398	33.45	6	294	20	287	2.0e-52	200	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
638027049	447	29.89	43	313	38	287	3.0e-46	179	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
638027055	243	28.99	1	237	2	239	2.0e-22	99	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
638027056	147	30.41	16	147	3	147	7.0e-22	96.6	COG0328	Ribonuclease HI	154
638027057	340	40.83	7	336	2	317	1.0e-55	210	COG4127	Predicted restriction endonuclease, Mrr-cat superfamily	318
638027059	426	55.31	7	420	3	412	2.0e-117	415	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
638027062	463	46.29	133	463	4	340	5.0e-97	348	COG0552	Signal recognition particle GTPase	340
638027067	507	30.16	1	364	4	360	5.0e-43	169	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
638027068	326	41.64	1	299	1	316	9.0e-68	250	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
638027071	458	45.98	39	378	27	368	8.0e-90	324	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
638027072	286	23.94	24	284	2	282	3.0e-20	92.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638027073	397	25.59	12	393	1	418	5.0e-36	145	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
638027074	300	35.74	4	300	3	297	2.0e-36	146	COG2177	Cell division protein FtsX	297
638027075	230	57.73	1	220	1	220	7.0e-83	300	COG2884	ABC-type ATPase involved in cell division	223
638027078	271	48.85	8	269	7	267	4.0e-83	301	COG0796	Glutamate racemase	269
638027080	236	34.11	21	232	5	211	1.0e-32	133	COG0811	Biopolymer transport protein ExbB/TolQ	216
638027081	153	48.91	1	137	1	137	2.0e-37	148	COG0848	Biopolymer transport protein ExbD	137
638027082	262	18.81	33	250	17	233	8.0e-08	51.3	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
638027083	431	33.41	5	428	3	425	1.0e-63	237	COG0823	Periplasmic component of the Tol biopolymer transport system	425
638027085	394	24.88	3	394	6	404	5.0e-48	185	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
638027087	422	21.63	34	407	42	432	2.0e-23	104	COG2271	Sugar phosphate permease	448
638027088	439	31.88	1	200	33	227	8.0e-17	81.9	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
638027090	1031	22.18	179	1031	26	765	6.0e-54	206	COG4775	Outer membrane protein assembly factor BamA	766
638027091	1294	16.31	83	1275	101	1268	3.0e-27	118	COG2911	Autotransporter translocation and assembly factor TamB	1278
638027092	314	35.61	1	261	7	266	2.0e-35	143	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
638027095	199	40.12	36	197	1	139	4.0e-23	101	COG0511	Biotin carboxyl carrier protein	140
638027096	192	49.22	5	132	4	131	9.0e-38	149	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
638027099	901	27.81	239	893	67	708	1.0e-64	242	COG4796	Type II secretory pathway, component HofQ	709
638027100	200	29.51	67	181	47	167	3.0e-09	55	COG3168	Tfp pilus assembly protein PilP	170
638027101	205	25.74	5	204	13	211	2.0e-20	92.7	COG3167	Tfp pilus assembly protein PilO	211
638027102	225	26.32	1	150	3	152	1.0e-10	60.3	COG3166	Tfp pilus assembly protein PilN	206
638027103	395	31.09	38	388	8	351	1.0e-60	227	COG4972	Tfp pilus assembly protein, ATPase PilM	354
638027104	474	50.75	5	469	5	460	0.0e+00	475	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638027106	335	45.41	13	229	2	218	6.0e-30	125	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
638027107	255	18.71	1	255	1	278	1.0e-07	50.1	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
638027108	326	35.08	13	314	5	292	1.0e-67	250	COG1131	ABC-type multidrug transport system, ATPase component	293
638027111	478	46.92	14	467	6	457	5.0e-130	458	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638027112	525	30.95	202	525	8	354	8.0e-42	165	COG3852	Signal transduction histidine kinase, nitrogen specific	363
638027113	417	40.1	19	417	4	397	9.0e-108	384	COG1459	Type II secretory pathway, component PulF	397
638027114	372	54.42	1	351	2	351	0.0e+00	468	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
638027115	566	50	60	557	3	494	0.0e+00	556	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
638027116	308	42.57	14	304	14	304	3.0e-80	292	COG0196	FAD synthase	304
638027117	206	32.46	13	199	29	219	2.0e-30	125	COG0220	tRNA G46 methylase TrmB	227
638027118	347	39.76	17	347	125	435	2.0e-66	246	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
638027122	988	29.31	283	958	5	638	8.0e-73	269	COG1199	Rad3-related DNA helicase	654
638027126	1798	20.95	1072	1671	12	659	3.0e-20	95.7	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
638027128	324	33.43	2	320	46	357	2.0e-47	183	COG1858	Cytochrome c peroxidase	364
638027129	898	52.11	1	895	2	878	0.0e+00	1057	COG0013	Alanyl-tRNA synthetase	879
638027131	1293	32.16	774	1217	7	436	3.0e-57	217	COG0443	Molecular chaperone DnaK (HSP70)	579
638027133	445	41.53	12	430	10	439	3.0e-90	325	COG3572	Gamma-glutamylcysteine synthetase	456
638027134	272	27.85	19	250	5	237	3.0e-13	69.1	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
638027135	1072	43.09	129	490	32	391	2.0e-81	298	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
638027137	241	36.55	1	237	6	254	6.0e-37	147	COG0584	Glycerophosphoryl diester phosphodiesterase	257
638027138	89	23.94	15	85	1	71	1.0e-06	44.6	COG1826	Sec-independent protein translocase protein TatA	94
638027142	273	32.94	7	258	1	250	2.0e-41	163	COG1192	Cellulose biosynthesis protein BcsQ	259
638027144	319	22.75	23	243	3	249	2.0e-23	103	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
638027145	371	24.31	12	368	1	306	8.0e-34	138	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
638027150	151	53.28	1	136	2	138	2.0e-42	164	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
638027153	687	30.71	23	683	13	649	9.0e-127	447	COG2766	Predicted Ser/Thr protein kinase	649
638027154	369	29.21	7	367	17	417	3.0e-69	255	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
638027155	497	32.86	9	487	15	487	8.0e-105	374	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
638027156	423	31.94	170	380	47	260	2.0e-31	130	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
638027158	834	47.64	29	827	7	748	0.0e+00	860	COG0058	Glucan phosphorylase	750
638027159	158	23.42	14	121	5	113	8.0e-07	46.5	COG4319	Ketosteroid isomerase homolog	137
638027163	687	33.44	54	673	26	669	4.0e-129	455	COG0339	Zn-dependent oligopeptidase	683
638027165	267	35.46	11	254	3	251	8.0e-37	147	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638027166	878	43.54	5	334	6	335	6.0e-84	306	COG0826	Collagenase-like protease, PrtC family	347
638027167	345	28.02	1	239	2	254	2.0e-27	116	COG0287	Prephenate dehydrogenase	279
638027167	345	37.65	255	338	6	90	1.0e-12	67.7	COG1605	Chorismate mutase	101
638027168	275	36.47	4	269	3	255	1.0e-54	206	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638027171	1185	50.74	1	1146	2	1106	0.0e+00	1304	COG0587	DNA polymerase III, alpha subunit	1139
638027176	288	32.43	1	72	2	75	2.0e-09	56.9	COG3831	WGR domain, predicted DNA-binding domain in MolR	85
638027177	334	27.78	4	332	1	314	6.0e-33	135	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638027178	402	27.39	37	402	22	389	4.0e-49	189	COG4552	Predicted acetyltransferase	389
638027179	990	20.35	1	505	1	493	1.0e-39	158	COG0591	Na+/proline symporter	493
638027180	460	49.68	1	459	4	460	0.0e+00	480	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638027183	654	41.8	69	623	1	522	0.0e+00	630	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
638027184	94	41.03	9	85	14	91	3.0e-12	63.3	COG3162	Uncharacterized membrane protein, DUF485 family	102
638027185	544	51.23	14	514	5	529	0.0e+00	462	COG4147	Na+(or H+)/acetate symporter ActP	529
638027187	237	27.93	1	193	13	233	7.0e-20	91.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
638027189	192	43.5	22	190	6	179	9.0e-35	140	COG2032	Cu/Zn superoxide dismutase	179
638027190	759	22.02	378	576	61	254	1.0e-08	55.8	COG5426	Uncharacterized membrane protein	254
638027197	278	39.63	1	266	73	334	9.0e-51	194	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
638027198	808	34.77	31	509	31	504	8.0e-103	368	COG0513	Superfamily II DNA and RNA helicase	513
638027199	170	31.07	18	119	2	104	8.0e-09	53.5	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
638027200	409	49.25	9	409	9	410	1.0e-130	459	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
638027201	405	53.64	1	341	6	346	1.0e-110	393	COG1171	Threonine dehydratase	347
638027204	204	45.55	2	191	3	192	1.0e-44	173	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
638027205	291	44.57	36	287	10	264	6.0e-59	221	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
638027210	398	37.91	8	396	2	390	1.0e-77	283	COG0183	Acetyl-CoA acetyltransferase	392
638027212	218	40.61	1	195	5	201	1.0e-31	129	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
638027217	139	58.77	2	114	3	116	2.0e-37	148	COG3189	Uncharacterized conserved protein YeaO, DUF488 family	117
638027218	551	33.13	47	534	5	472	5.0e-87	315	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638027219	282	22.62	3	281	4	304	3.0e-28	119	COG2017	Galactose mutarotase or related enzyme	308
638027220	379	39.16	49	379	2	318	5.0e-74	271	COG2826	Transposase and inactivated derivatives, IS30 family	318
638027221	301	28.52	13	298	1	289	7.0e-24	104	COG0583	DNA-binding transcriptional regulator, LysR family	297
638027222	411	31.02	1	400	1	384	4.0e-65	241	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638027223	274	33.64	6	223	9	223	1.0e-42	166	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
638027224	357	33.03	13	338	2	313	2.0e-49	190	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
638027225	230	25.99	1	220	2	203	4.0e-17	81.8	COG0406	Broad specificity phosphatase PhoE	208
638027226	306	34.94	132	294	1	166	5.0e-34	138	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
638027229	439	37.5	95	411	54	367	1.0e-61	230	COG2021	Homoserine acetyltransferase	368
638027230	365	27.45	127	324	3	204	3.0e-18	86.5	COG0569	Trk K+ transport system, NAD-binding component	225
638027232	182	36.76	1	68	1	68	3.0e-12	65.4	COG1826	Sec-independent protein translocase protein TatA	94
638027233	425	22.78	1	395	3	391	2.0e-32	133	COG2814	Predicted arabinose efflux permease, MFS family	394
638027234	723	34.87	332	635	104	404	5.0e-39	156	COG0840	Methyl-accepting chemotaxis protein	408
638027235	347	42.86	7	344	1	339	1.0e-85	310	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
638027236	253	32.82	1	252	1	259	3.0e-45	175	COG0300	Short-chain dehydrogenase	265
638027237	288	24.72	10	272	2	232	3.0e-16	79.6	COG0284	Orotidine-5'-phosphate decarboxylase	240
638027238	843	39.9	14	825	1	766	0.0e+00	669	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
638027239	318	38.69	1	303	1	287	5.0e-67	247	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
638027242	325	23.1	29	307	54	405	6.0e-29	121	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
638027243	351	25.94	55	341	1	292	1.0e-10	61.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
638027244	188	24.48	24	158	1	139	8.0e-08	50.7	COG1247	L-amino acid N-acyltransferase YncA	169
638027246	321	47.81	4	319	3	312	5.0e-80	291	COG2025	Electron transfer flavoprotein, alpha subunit	313
638027247	265	45.82	1	264	1	259	7.0e-61	227	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
638027248	395	44.85	18	395	1	388	2.0e-98	352	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638027249	223	52.4	1	216	8	236	4.0e-67	247	COG0176	Transaldolase	239
638027250	352	51.05	35	223	2	191	8.0e-51	194	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
638027252	174	46.79	4	158	3	157	4.0e-41	161	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
638027253	256	44.92	9	256	11	266	2.0e-68	252	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
638027254	271	51.49	1	267	2	266	4.0e-79	287	COG0289	Dihydrodipicolinate reductase	266
638027255	295	46.96	1	293	2	296	3.0e-81	295	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
638027256	413	50.51	1	390	1	394	7.0e-112	397	COG0019	Diaminopimelate decarboxylase	394
638027259	290	34.67	1	267	1	273	3.0e-56	212	COG0266	Formamidopyrimidine-DNA glycosylase	273
638027261	348	31.38	1	287	6	295	2.0e-50	192	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
638027262	295	36.61	2	250	16	262	2.0e-51	195	COG0005	Purine nucleoside phosphorylase	262
638027264	215	44.39	15	209	11	194	3.0e-42	165	COG3145	Alkylated DNA repair dioxygenase AlkB	194
638027265	267	74.12	40	267	9	236	2.0e-96	345	COG3826	Uncharacterized protein	236
638027266	325	26.92	22	307	11	292	3.0e-09	56	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
638027267	339	40.76	7	336	4	337	3.0e-67	249	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
638027268	186	55.14	1	185	5	184	1.0e-56	212	COG2096	Cob(I)alamin adenosyltransferase	184
638027269	267	67.04	3	267	2	268	3.0e-115	408	COG0207	Thymidylate synthase	268
638027270	159	42.17	2	159	1	166	1.0e-39	156	COG0262	Dihydrofolate reductase	167
638027276	326	29.77	77	268	27	234	3.0e-17	83	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
638027277	431	29.16	3	420	6	408	3.0e-54	206	COG1078	HD superfamily phosphohydrolase	421
638027278	376	33.99	101	344	78	317	3.0e-31	129	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
638027279	155	28.79	1	128	4	128	3.0e-06	44.5	COG3153	Predicted N-acetyltransferase YhbS	171
638027281	696	45.43	5	693	1	666	0.0e+00	675	COG1331	Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains	667
638027283	343	25.64	4	213	5	238	8.0e-22	98.4	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
638027286	329	18.83	13	328	43	412	2.0e-09	56.6	COG5379	S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase	414
638027287	319	21.61	11	304	15	315	1.0e-28	120	COG3239	Fatty acid desaturase	343
638027290	213	30	17	212	11	206	1.0e-29	123	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
638027293	267	32.47	26	246	10	237	5.0e-36	144	COG4021	tRNA(His) 5'-end guanylyltransferase	249
638027294	185	25.53	32	159	4	142	5.0e-11	61.2	COG4639	Predicted kinase	168
638027297	639	34.04	6	619	93	742	1.0e-81	298	COG1112	Superfamily I DNA and/or RNA helicase	767
638027299	284	28.2	25	284	19	280	4.0e-17	82.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638027301	401	29.69	19	292	2	279	2.0e-33	137	COG0515	Serine/threonine protein kinase	384
638027302	133	31.73	17	119	1	101	2.0e-15	75.1	COG3791	Uncharacterized conserved protein	133
638027303	274	26.36	12	264	36	285	3.0e-29	122	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
638027305	284	33.07	10	257	1	244	3.0e-44	172	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
638027306	389	28.69	18	381	8	359	4.0e-41	162	COG0349	Ribonuclease D	361
638027307	939	26.54	81	929	6	853	4.0e-92	333	COG0308	Aminopeptidase N	859
638027308	213	41.47	3	213	4	218	3.0e-45	175	COG4122	Predicted O-methyltransferase YrrM	219
638027313	501	44.88	9	495	10	497	0.0e+00	525	COG2317	Zn-dependent carboxypeptidase, M32 family	497
638027317	541	54.27	1	526	1	524	0.0e+00	742	COG4108	Peptide chain release factor RF-3	528
638027318	131	37.69	1	129	2	130	2.0e-24	104	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
638027320	231	43.48	8	228	2	229	4.0e-51	194	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638027321	463	28.12	118	462	4	335	3.0e-31	129	COG0642	Signal transduction histidine kinase	336
638027325	318	35.31	18	317	35	320	2.0e-57	216	COG4607	ABC-type enterochelin transport system, periplasmic component	320
638027326	268	41.13	4	268	2	260	1.0e-45	176	COG3694	ABC-type uncharacterized transport system, permease component	260
638027327	267	30.94	6	267	4	268	5.0e-33	135	COG4587	ABC-type uncharacterized transport system, permease component	268
638027328	335	45.2	1	323	3	325	8.0e-96	343	COG4586	ABC-type uncharacterized transport system, ATPase component	325
638027331	322	24.91	21	305	2	265	2.0e-18	86.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638027332	296	31.68	40	239	21	218	1.0e-19	90.4	COG4377	Uncharacterized membrane protein YhfC	258
638027333	611	32.13	283	601	23	319	7.0e-49	189	COG3469	Chitinase	332
638027334	1021	31.71	66	331	2	273	1.0e-40	162	COG0515	Serine/threonine protein kinase	384
638027336	468	26.86	13	466	9	409	2.0e-52	200	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
638027341	345	25.18	66	345	6	231	2.0e-17	83.8	COG1018	Ferredoxin-NADP reductase	266
638027342	250	32.71	36	245	53	254	7.0e-22	97.7	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
638027343	383	37.97	13	376	4	372	3.0e-70	259	COG0116	23S rRNA G2445 N2-methylase RlmL	381
638027344	559	42.06	336	559	60	289	2.0e-51	197	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
638027346	188	58.33	119	188	13	84	6.0e-21	93.9	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
638027349	403	47.76	25	402	9	386	8.0e-114	404	COG3146	Predicted N-acyltransferase	387
638027350	107	51.14	18	105	20	107	2.0e-25	107	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
638027351	765	46.16	8	760	4	786	0.0e+00	814	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
638027352	531	28.69	165	530	47	408	1.0e-35	144	COG0840	Methyl-accepting chemotaxis protein	408
638027353	355	40.12	7	340	2	344	2.0e-73	269	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
638027354	714	31.73	52	570	188	699	3.0e-83	303	COG0643	Chemotaxis protein histidine kinase CheA	716
638027355	182	21.34	23	182	2	164	7.0e-11	60.3	COG0835	Chemotaxis signal transduction protein	165
638027356	413	32.23	10	245	4	244	1.0e-41	164	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
638027359	272	43.3	1	258	2	258	1.0e-73	270	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
638027360	963	51.94	4	954	5	903	0.0e+00	1153	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
638027361	398	50.12	1	397	1	404	7.0e-112	397	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
638027362	68	70.15	1	67	1	67	8.0e-24	101	COG1278	Cold shock protein, CspA family	67
638027363	734	25.39	116	734	19	617	1.0e-58	221	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
638027367	289	28.41	13	271	49	316	1.0e-32	133	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
638027368	545	33.57	28	296	2	273	6.0e-44	172	COG0515	Serine/threonine protein kinase	384
638027369	682	22.09	14	650	21	657	1.0e-41	165	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
638027372	208	40.8	4	204	6	205	3.0e-40	158	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
638027373	329	42.2	20	299	1	265	2.0e-60	226	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
638027374	262	21.32	16	237	38	288	1.0e-14	74	COG3239	Fatty acid desaturase	343
638027376	654	51.19	8	633	3	619	0.0e+00	734	COG0326	Molecular chaperone, HSP90 family	623
638027378	485	34.23	153	485	3	329	8.0e-46	178	COG0642	Signal transduction histidine kinase	336
638027380	470	44.37	30	453	7	390	2.0e-97	350	COG3004	Na+/H+ antiporter NhaA	390
638027381	292	27.6	48	279	14	256	7.0e-25	108	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
638027382	139	52.31	7	136	3	132	2.0e-43	168	COG3607	Predicted lactoylglutathione lyase	133
638027383	326	31.35	1	183	5	168	7.0e-28	118	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638027385	464	25.21	50	464	2	484	2.0e-21	97.5	COG1233	Phytoene dehydrogenase-related protein	487
638027386	341	58.74	55	335	1	286	5.0e-100	358	COG2876	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	286
638027387	338	54.49	1	334	2	334	8.0e-107	380	COG0547	Anthranilate phosphoribosyltransferase	338
638027388	262	47.08	7	256	1	254	1.0e-66	246	COG0134	Indole-3-glycerol phosphate synthase	254
638027389	212	49.52	3	207	2	207	2.0e-52	198	COG0135	Phosphoribosylanthranilate isomerase	208
638027390	401	67.19	8	388	7	386	0.0e+00	623	COG0133	Tryptophan synthase beta chain	396
638027391	263	46.77	5	263	4	265	4.0e-74	271	COG0159	Tryptophan synthase alpha chain	265
638027395	201	35.61	9	201	3	204	2.0e-31	128	COG0406	Broad specificity phosphatase PhoE	208
638027396	187	59.89	1	184	3	189	8.0e-74	269	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
638027397	497	47.5	21	494	1	460	1.0e-128	453	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
638027398	350	23.96	39	348	44	424	2.0e-35	143	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
638027399	531	30.44	65	526	6	442	4.0e-66	246	COG1793	ATP-dependent DNA ligase	444
638027400	860	31.9	55	851	10	796	0.0e+00	534	COG1201	Lhr-like helicase	814
638027401	217	32.98	22	208	14	203	9.0e-25	106	COG1407	Metallophosphoesterase superfamily enzyme	235
638027404	1064	26.75	819	1043	10	193	3.0e-38	154	COG0437	Fe-S-cluster-containing dehydrogenase component	203
638027405	479	22.03	50	450	23	392	7.0e-20	92.3	COG5557	Ni/Fe-hydrogenase 2 integral membrane subunit HybB	401
638027410	293	21.4	11	219	1	193	4.0e-17	82.4	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
638027411	348	32.19	7	232	16	243	2.0e-41	162	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
638027412	556	43.46	33	544	7	525	1.0e-126	447	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
638027413	222	31.19	5	222	4	206	6.0e-31	127	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
638027422	328	45.35	2	324	12	343	3.0e-75	275	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
638027425	159	27.74	9	159	1	148	2.0e-06	45.2	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
638027426	459	38.39	45	456	1	411	3.0e-79	289	COG1061	Superfamily II DNA or RNA helicase	442
638027427	401	24.87	1	367	1	356	5.0e-28	118	COG3372	Predicted nuclease of restriction endonuclease-like (RecB) superfamily, implicated in nucleotide excision repair	396
638027430	276	21.86	1	266	1	268	6.0e-14	71.5	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
638027431	744	35.99	81	519	46	507	5.0e-78	286	COG3227	Zn-dependent metalloprotease	507
638027432	325	41.77	1	322	1	326	2.0e-59	222	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
638027434	370	27.02	2	359	1	273	2.0e-25	110	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
638027435	194	40	1	193	4	193	5.0e-25	107	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
638027437	214	35.68	7	210	5	217	9.0e-35	140	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
638027439	1095	24.74	63	251	47	214	2.0e-09	58.6	COG2114	Adenylate cyclase, class 3	227
638027439	1095	34.5	294	716	10	406	5.0e-31	130	COG3903	Predicted ATPase	414
638027442	565	21.46	99	331	1	232	3.0e-09	57.3	COG2202	PAS domain	232
638027445	271	46.54	4	256	7	266	5.0e-68	251	COG4295	Uncharacterized protein	285
638027447	202	33.64	1	201	1	211	2.0e-32	132	COG0625	Glutathione S-transferase	211
638027448	119	24.81	1	116	2	125	3.0e-07	47.6	COG3607	Predicted lactoylglutathione lyase	133
638027451	453	33.33	2	401	1	366	1.0e-46	180	COG5659	SRSO17 transposase	385
638027453	276	23.57	3	273	1	297	7.0e-13	68.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
638027460	185	19.79	3	185	1	165	5.0e-10	57.6	COG0262	Dihydrofolate reductase	167
638027463	480	29.26	24	472	29	457	2.0e-61	230	COG5361	Uncharacterized conserved protein	458
638027465	482	22.86	43	481	8	456	2.0e-32	134	COG0277	FAD/FMN-containing dehydrogenase	459
638027470	218	38.97	1	213	1	209	5.0e-47	180	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
638027471	1080	22.99	51	667	42	604	5.0e-22	100	COG3292	Periplasmic ligand-binding sensor domain	671
638027476	113	71.82	4	113	3	112	2.0e-44	170	COG2824	Uncharacterized Zn-ribbon-containing protein	112
638027477	388	42.73	2	220	10	219	1.0e-29	124	COG0785	Cytochrome c biogenesis protein CcdA	220
638027478	302	30.33	7	302	3	292	1.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
638027480	260	36.33	4	251	2	249	7.0e-33	134	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638027481	326	26.9	12	318	3	298	8.0e-32	131	COG2040	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)	300
638027482	247	43.29	9	239	7	236	2.0e-55	209	COG2188	DNA-binding transcriptional regulator, GntR family	236
638027483	288	29.18	1	280	2	256	2.0e-12	66.2	COG0730	Uncharacterized membrane protein YfcA	258
638027487	306	33.56	7	290	26	313	2.0e-50	193	COG1171	Threonine dehydratase	347
638027488	299	31.74	5	294	2	288	1.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
638027489	614	33.23	1	596	12	606	1.0e-103	370	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
638027490	361	28.45	1	347	1	333	2.0e-33	136	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
638027491	341	40.06	1	312	1	310	3.0e-70	258	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
638027494	177	24.86	8	172	1	177	7.0e-11	60.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638027497	458	21.92	16	456	43	457	9.0e-18	85.2	COG1538	Outer membrane protein TolC	457
638027498	1047	27.9	2	1019	1	1004	0.0e+00	563	COG0841	Multidrug efflux pump subunit AcrB	1009
638027499	374	26.98	8	371	2	365	1.0e-25	110	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
638027502	463	49.75	32	429	1	401	5.0e-114	404	COG0004	Ammonia channel protein AmtB	409
638027503	227	25.32	15	164	12	152	6.0e-10	57.7	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
638027504	671	32.06	19	286	2	277	2.0e-43	171	COG0515	Serine/threonine protein kinase	384
638027507	471	53.19	176	457	1	262	3.0e-88	319	COG1760	L-serine deaminase	262
638027509	716	56.63	16	520	1	496	0.0e+00	691	COG0753	Catalase	496
638027513	848	22.01	65	319	11	229	3.0e-11	64.3	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
638027514	557	27.7	19	539	12	520	5.0e-55	209	COG4365	Uncharacterized protein YllA, UPF0747 family	537
638027515	268	28.17	1	246	2	236	5.0e-28	118	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
638027516	387	28.87	7	381	6	378	6.0e-35	142	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638027520	311	38.91	1	310	4	332	5.0e-77	281	COG3938	Proline racemase	341
638027521	378	31.78	1	367	2	381	5.0e-37	148	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
638027523	425	27.97	6	306	5	293	7.0e-21	95.4	COG0492	Thioredoxin reductase	305
638027524	296	37.97	1	291	2	295	6.0e-64	237	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
638027525	524	26.48	16	494	11	466	2.0e-46	180	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638027527	271	34.31	153	254	19	120	2.0e-19	90.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638027530	295	40.14	8	281	64	333	2.0e-56	212	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
638027532	274	31.33	1	238	1	235	5.0e-37	148	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
638027536	124	34.26	1	106	3	110	8.0e-10	56	COG0640	DNA-binding transcriptional regulator, ArsR family	110
638027543	244	47.77	1	244	1	245	2.0e-73	268	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
638027544	427	25.53	100	425	14	336	1.0e-30	127	COG0642	Signal transduction histidine kinase	336
638027545	183	50.55	1	182	4	182	3.0e-46	177	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
638027552	98	28.57	1	98	12	97	7.0e-07	45.6	COG0640	DNA-binding transcriptional regulator, ArsR family	110
638027553	394	32.12	1	384	9	393	2.0e-54	206	COG2814	Predicted arabinose efflux permease, MFS family	394
638027562	158	51.61	1	149	3	151	2.0e-45	175	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
638027565	538	33.33	365	532	26	186	2.0e-31	131	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
638027570	195	33.73	5	169	2	167	3.0e-06	45.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638027575	179	25	1	177	1	188	1.0e-07	49.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638027576	386	33.96	99	359	1	252	3.0e-44	172	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
638027580	427	19.4	154	419	69	305	8.0e-08	52.1	COG3344	Retron-type reverse transcriptase	328
638027581	139	34.75	10	126	4	117	6.0e-16	76.6	COG3791	Uncharacterized conserved protein	133
638027582	442	29.67	21	384	23	338	4.0e-54	205	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
638027584	411	27.53	6	397	1	386	3.0e-41	163	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
638027585	602	30.02	18	542	14	510	2.0e-80	293	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
638027587	139	32.97	1	85	1	91	2.0e-09	55.1	COG3293	Transposase	124
638027591	597	21.67	12	248	43	252	3.0e-15	77	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
638027592	117	44.21	1	93	15	109	2.0e-06	44.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
638027593	170	35.57	19	164	6	147	5.0e-21	94	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
638027594	387	30.23	90	385	8	312	4.0e-27	115	COG0657	Acetyl esterase/lipase	312
638027598	278	26.7	1	218	3	223	7.0e-21	94.8	COG1378	Sugar-specific transcriptional regulator TrmB	247
638027600	501	29.79	224	500	12	295	6.0e-35	142	COG2342	Endo alpha-1,4 polygalactosaminidase, GH114 family (was erroneously annotated as Cys-tRNA synthetase)	300
638027601	395	34.5	134	388	17	265	3.0e-32	133	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
638027602	512	30.42	31	313	1	278	1.0e-31	131	COG4584	Transposase	278
638027603	253	30.92	1	246	5	253	1.0e-40	160	COG1484	DNA replication protein DnaC	254
638027606	381	23.42	102	322	2	220	4.0e-16	79.3	COG4912	3-methyladenine DNA glycosylase AlkD	222
638027609	401	34.38	8	382	11	368	3.0e-45	175	COG5659	SRSO17 transposase	385
638027613	219	59.45	3	219	1	215	1.0e-88	319	COG0036	Pentose-5-phosphate-3-epimerase	220
638027615	477	53.56	1	475	4	477	0.0e+00	560	COG0469	Pyruvate kinase	477
638027619	435	31.64	5	420	1	451	2.0e-73	269	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
638027620	337	44.55	1	314	1	318	2.0e-83	302	COG0042	tRNA-dihydrouridine synthase	323
638027621	475	25.33	1	221	5	215	4.0e-10	59.6	COG1994	Zn-dependent protease (includes SpoIVFB)	230
638027622	354	37.29	43	273	48	283	5.0e-49	188	COG1398	Fatty-acid desaturase	289
638027623	677	37.26	94	514	1	414	1.0e-58	221	COG0038	H+/Cl- antiporter ClcA	443
638027624	396	22.28	37	383	14	379	6.0e-23	102	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638027625	170	38.71	18	140	1	120	2.0e-17	81.9	COG5628	Predicted acetyltransferase	143
638027626	176	36.57	16	142	4	135	6.0e-27	113	COG1225	Peroxiredoxin	157
638027627	430	30.47	1	404	2	416	3.0e-38	153	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
638027628	691	24.21	4	331	2	332	5.0e-33	136	COG0515	Serine/threonine protein kinase	384
638027629	340	35.37	48	339	21	309	6.0e-44	171	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
638027630	249	32.68	4	245	3	257	4.0e-35	141	COG3394	Predicted glycoside hydrolase or deacetylase ChbG, UPF0249 family	257
638027632	134	45.95	21	131	28	138	3.0e-33	133	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
638027633	389	33.33	42	297	2	277	1.0e-44	174	COG0515	Serine/threonine protein kinase	384
638027635	377	30.95	26	363	61	438	7.0e-44	171	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
638027638	505	38.19	6	446	1	446	2.0e-85	310	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
638027639	406	34.89	1	402	2	350	1.0e-71	263	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
638027640	364	31.59	27	362	16	343	9.0e-50	191	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
638027641	242	31.9	6	230	7	234	1.0e-29	123	COG0300	Short-chain dehydrogenase	265
638027642	185	31.58	12	68	4	60	6.0e-08	51	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
638027651	719	25	301	556	72	329	1.0e-18	88.7	COG0642	Signal transduction histidine kinase	336
638027653	334	52.03	3	334	2	345	7.0e-117	413	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
638027654	104	33.33	24	104	23	102	1.0e-11	61.4	COG0023	Translation initiation factor 1 (eIF-1/SUI1)	104
638027657	356	31.58	6	354	10	369	4.0e-47	182	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
638027662	403	38.14	20	210	2	195	7.0e-33	135	COG2059	Chromate transport protein ChrA	195
638027663	219	29.63	4	216	1	209	2.0e-27	115	COG0625	Glutathione S-transferase	211
638027664	326	22.6	4	326	1	266	1.0e-34	140	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
638027671	417	38.27	21	341	5	321	2.0e-76	279	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
638027672	468	40.22	13	466	1	456	3.0e-82	299	COG0277	FAD/FMN-containing dehydrogenase	459
638027684	242	28.86	25	223	5	194	2.0e-08	53.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638027686	242	42.51	1	242	1	236	1.0e-53	203	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
638027687	475	38.3	1	471	1	474	7.0e-101	361	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
638027688	345	45.83	1	332	3	319	1.0e-87	316	COG0205	6-phosphofructokinase	347
638027689	547	35.34	1	542	1	534	4.0e-118	418	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
638027698	426	25.7	145	417	6	284	4.0e-31	129	COG1408	Predicted phosphohydrolase, MPP superfamily	284
638027699	223	37.5	6	215	4	219	1.0e-44	173	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
638027700	368	48.35	8	363	3	346	9.0e-112	396	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
638027701	294	40.64	4	250	14	262	3.0e-64	238	COG0005	Purine nucleoside phosphorylase	262
638027702	269	19.35	53	258	70	285	2.0e-08	52.8	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
638027703	1089	28.92	186	1082	102	960	0.0e+00	524	COG4403	Lantibiotic modifying enzyme	963
638027705	411	36.14	1	407	3	409	4.0e-55	209	COG4102	Uncharacterized conserved protein, DUF1501 family	418
638027708	160	43.92	12	157	4	140	2.0e-32	132	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
638027709	256	21.16	1	241	10	211	1.0e-12	67.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
638027710	403	41.56	5	396	4	412	7.0e-90	324	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
638027711	340	27.58	1	316	1	359	2.0e-35	143	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
638027712	163	30.95	28	148	14	137	8.0e-13	66.8	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
638027713	249	33.47	15	248	3	250	1.0e-22	100	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638027714	258	44.27	11	257	2	251	2.0e-46	179	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638027715	411	42.48	1	410	1	412	1.0e-104	373	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
638027716	411	34.31	12	409	4	409	7.0e-63	234	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
638027717	227	50.45	2	224	1	224	1.0e-73	269	COG1136	ABC-type lipoprotein export system, ATPase component	226
638027718	408	21.88	4	405	7	405	8.0e-32	131	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
638027724	524	21.52	12	393	2	378	6.0e-26	112	COG1680	CubicO group peptidase, beta-lactamase class C family	390
638027725	574	36.71	154	574	113	496	2.0e-76	280	COG5267	Uncharacterized conserved protein, DUF1800 family	496
638027728	233	46.96	8	232	3	229	3.0e-52	198	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638027729	607	27.63	274	602	1	328	4.0e-29	123	COG0642	Signal transduction histidine kinase	336
638027731	218	42.86	36	215	29	210	4.0e-44	171	COG2173	D-alanyl-D-alanine dipeptidase	211
638027732	230	52.17	1	228	1	221	4.0e-72	264	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
638027735	830	34.52	13	276	2	277	1.0e-46	181	COG0515	Serine/threonine protein kinase	384
638027740	240	34.3	33	239	5	211	4.0e-48	184	COG0177	Endonuclease III	211
638027743	1216	27.82	111	367	2	279	1.0e-36	149	COG0515	Serine/threonine protein kinase	384
638027747	660	26.93	52	473	5	393	3.0e-33	136	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638027748	161	27.83	31	145	4	115	6.0e-06	43.8	COG4922	Predicted SnoaL-like aldol condensation-catalyzing enzyme	129
638027750	478	28.05	19	471	22	478	2.0e-57	217	COG4784	Putative Zn-dependent protease	479
638027753	203	68.18	1	198	2	199	4.0e-82	297	COG0740	ATP-dependent protease ClpP, protease subunit	200
638027754	466	69.06	5	463	2	460	0.0e+00	769	COG0114	Fumarate hydratase class II	462
638027755	133	27.12	47	103	5	63	6.0e-07	46.7	COG1983	Phage shock protein PspC (stress-responsive transcriptional regulator)	70
638027756	541	47.15	28	541	25	545	0.0e+00	578	COG2225	Malate synthase	545
638027757	428	72.12	21	428	20	433	0.0e+00	626	COG2224	Isocitrate lyase	433
638027764	427	25.34	1	421	15	443	2.0e-53	203	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
638027765	531	23.84	131	405	6	327	2.0e-23	103	COG1680	CubicO group peptidase, beta-lactamase class C family	390
638027768	341	34.69	1	340	1	336	5.0e-58	218	COG3138	Arginine/ornithine N-succinyltransferase beta subunit	336
638027770	1048	24.43	73	461	11	401	1.0e-33	138	COG0840	Methyl-accepting chemotaxis protein	408
638027770	1048	28.99	577	1042	54	553	1.0e-60	228	COG0747	ABC-type transport system, periplasmic component	556
638027772	206	25.77	8	201	11	203	1.0e-20	93	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
638027773	358	34.69	2	338	3	341	1.0e-66	246	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
638027775	217	40.32	22	207	1	176	1.0e-27	116	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638027776	194	48.97	1	184	3	193	6.0e-48	183	COG2094	3-methyladenine DNA glycosylase Mpg	200
638027777	516	31.71	6	507	12	512	1.0e-88	321	COG1640	4-alpha-glucanotransferase	520
638027778	715	21.46	38	662	172	752	9.0e-50	192	COG4775	Outer membrane protein assembly factor BamA	766
638027779	1556	18.22	262	1548	125	1272	4.0e-31	131	COG2911	Autotransporter translocation and assembly factor TamB	1278
638027781	312	33.56	8	299	3	295	3.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
638027788	328	34.86	1	325	2	293	2.0e-67	249	COG1131	ABC-type multidrug transport system, ATPase component	293
638027790	316	48.6	2	311	15	326	3.0e-57	215	COG0714	MoxR-like ATPase	329
638027792	303	29.69	169	295	1	127	4.0e-15	75.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638027794	160	37.61	37	145	14	122	9.0e-17	80	COG4270	Uncharacterized membrane protein	131
638027795	332	44.34	1	322	1	316	2.0e-78	286	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
638027796	240	32.54	18	222	7	210	1.0e-26	113	COG0811	Biopolymer transport protein ExbB/TolQ	216
638027797	144	36.76	1	134	1	135	5.0e-22	96.8	COG0848	Biopolymer transport protein ExbD	137
638027798	268	27.31	54	268	47	244	1.0e-10	60.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
638027799	163	33.07	37	160	1	125	9.0e-12	63.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
638027800	467	27.57	1	422	23	443	4.0e-30	126	COG1538	Outer membrane protein TolC	457
638027804	941	40.63	27	921	23	915	0.0e+00	786	COG0474	Magnesium-transporting ATPase (P-type)	917
638027805	361	32.12	5	358	2	341	6.0e-49	188	COG0673	Predicted dehydrogenase	342
638027809	219	28.95	49	197	1	138	1.0e-09	57.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
638027810	171	59.24	8	160	4	158	7.0e-48	183	COG2077	Peroxiredoxin	158
638027811	310	34.08	1	310	6	306	6.0e-42	164	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
638027812	183	41.71	4	178	1	168	8.0e-32	130	COG0431	NAD(P)H-dependent FMN reductase	184
638027813	456	36.04	5	450	9	460	5.0e-102	365	COG1109	Phosphomannomutase	464
638027814	686	30	44	295	8	280	5.0e-33	136	COG0515	Serine/threonine protein kinase	384
638027815	354	45.35	3	331	2	333	2.0e-110	392	COG0836	Mannose-1-phosphate guanylyltransferase	333
638027817	471	31.73	8	397	7	393	9.0e-66	244	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
638027818	472	30.12	38	460	34	454	3.0e-54	206	COG4325	Uncharacterized membrane protein	464
638027819	629	33.76	12	560	2	544	1.0e-95	344	COG0659	Sulfate permease or related transporter, MFS superfamily	554
638027820	580	35.87	12	561	7	549	1.0e-102	367	COG0659	Sulfate permease or related transporter, MFS superfamily	554
638027821	553	34.2	18	461	2	438	5.0e-81	295	COG3119	Arylsulfatase A or related enzyme	475
638027822	426	26.07	18	250	17	250	9.0e-22	98.4	COG2966	Uncharacterized membrane protein YjjP, DUF1212 family	250
638027824	144	45.24	1	124	1	123	2.0e-35	141	COG3795	Uncharacterized conserved protein	123
638027828	297	42.44	1	269	4	270	5.0e-63	234	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
638027829	156	34.85	3	134	1	127	2.0e-20	91.5	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
638027830	476	55.6	8	468	1	420	0.0e+00	614	COG0499	S-adenosylhomocysteine hydrolase	420
638027831	396	64.52	1	383	1	387	0.0e+00	616	COG0192	S-adenosylmethionine synthetase	388
638027832	191	21.54	7	182	8	199	3.0e-09	55.3	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
638027833	712	27.25	49	711	31	674	4.0e-103	369	COG4389	Site-specific recombinase	677
638027834	894	18.54	17	871	5	727	7.0e-45	176	COG1033	Predicted exporter protein, RND superfamily	727
638027837	54	50	4	53	1	50	6.0e-09	52.5	COG0267	Ribosomal protein L33	50
638027838	415	40.05	10	379	1	323	3.0e-87	315	COG0523	GTPase, G3E family	323
638027840	78	51.95	1	76	1	77	3.0e-17	79.9	COG0227	Ribosomal protein L28	77
638027841	101	57.38	41	101	1	61	4.0e-13	66	COG0199	Ribosomal protein S14	61
638027843	617	45.86	10	576	2	567	0.0e+00	599	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
638027844	96	44.83	9	95	2	88	5.0e-20	89.5	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
638027846	238	27.86	5	204	4	195	8.0e-13	67.5	COG3715	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC	265
638027847	161	26.75	1	153	2	156	2.0e-28	118	COG3444	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB	159
638027848	139	41.01	1	137	1	139	6.0e-24	103	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
638027849	167	43.67	4	156	1	156	6.0e-39	153	COG1225	Peroxiredoxin	157
638027854	306	23.91	82	304	57	261	1.0e-05	44.2	COG0061	NAD kinase	281
638027856	336	27.49	107	295	3	197	7.0e-13	68.3	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
638027858	392	23.88	10	371	1	362	7.0e-37	148	COG0515	Serine/threonine protein kinase	384
638027860	669	16.58	1	661	16	766	3.0e-17	84.2	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
638027862	408	37.46	84	397	4	314	2.0e-51	196	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
638027864	546	26.24	1	523	14	544	4.0e-65	242	COG0747	ABC-type transport system, periplasmic component	556
638027865	326	39.38	1	325	2	316	4.0e-73	268	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
638027866	586	35.84	1	275	11	287	4.0e-53	203	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
638027866	586	44.28	301	567	1	271	9.0e-88	318	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
638027867	331	44.12	2	303	1	302	6.0e-95	341	COG4608	ABC-type oligopeptide transport system, ATPase component	309
638027868	456	42.49	1	454	1	459	0.0e+00	464	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
638027874	951	25.63	85	391	2	288	6.0e-35	143	COG0515	Serine/threonine protein kinase	384
638027877	287	48.07	7	287	2	286	7.0e-94	337	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
638027878	321	40.58	2	313	1	308	7.0e-77	280	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
638027879	116	40	2	116	1	112	2.0e-26	110	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
638027882	260	45.64	3	242	1	241	3.0e-68	251	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
638027883	1243	25.51	39	415	2	382	6.0e-37	150	COG0515	Serine/threonine protein kinase	384
638027884	561	23.56	330	553	9	219	1.0e-13	72.1	COG2114	Adenylate cyclase, class 3	227
638027885	163	31.85	1	150	9	155	5.0e-11	61	COG0723	Rieske Fe-S protein	177
638027888	361	40.76	21	356	3	331	5.0e-44	171	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
638027889	299	26.45	15	292	7	315	9.0e-31	127	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
638027891	669	22.39	1	642	1	604	1.0e-40	161	COG4206	Outer membrane cobalamin receptor protein	608
638027896	481	20.85	215	468	33	271	5.0e-07	49.6	COG3386	Sugar lactone lactonase YvrE	307
638027897	395	26.33	7	393	2	379	2.0e-34	140	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
638027898	864	37.76	560	851	54	336	2.0e-38	154	COG0642	Signal transduction histidine kinase	336
638027901	567	22.49	25	504	1	455	9.0e-53	201	COG4690	Dipeptidase	464
638027904	187	34.17	46	165	7	126	4.0e-12	64.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
638027908	144	37.76	7	104	10	106	2.0e-14	71.9	COG4828	Uncharacterized membrane protein	113
638027909	273	24	101	250	26	165	4.0e-09	55.5	COG3652	Predicted outer membrane protein	170
638027911	730	29.14	74	727	3	616	2.0e-98	354	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
638027912	218	31.51	14	218	3	221	5.0e-38	151	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
638027914	1146	38.94	600	1124	2	506	5.0e-115	409	COG0443	Molecular chaperone DnaK (HSP70)	579
638027916	339	28.74	1	337	4	337	4.0e-53	202	COG1559	Cell division protein YceG, involved in septum cleavage	342
638027917	263	42.46	7	257	6	255	6.0e-40	157	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638027919	342	42.38	23	341	9	326	6.0e-64	238	COG0714	MoxR-like ATPase	329
638027925	361	25.56	220	351	2	125	8.0e-15	75	COG3597	Uncharacterized conserved protein, DUF697 family	139
638027926	461	42.55	1	456	29	489	4.0e-109	388	COG0513	Superfamily II DNA and RNA helicase	513
638027928	500	28.93	10	236	3	242	1.0e-21	98.3	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
638027930	369	39.53	12	353	8	339	1.0e-69	256	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
638027933	274	60.78	1	153	1	153	3.0e-54	205	COG1225	Peroxiredoxin	157
638027937	334	22.12	125	326	16	222	1.0e-05	44.5	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
638027938	490	25.83	193	489	1	288	3.0e-26	113	COG0382	4-hydroxybenzoate polyprenyltransferase	289
638027939	464	19.76	29	426	53	446	5.0e-34	139	COG0277	FAD/FMN-containing dehydrogenase	459
638027940	245	25.6	1	243	6	255	6.0e-32	131	COG0300	Short-chain dehydrogenase	265
638027942	424	34.36	160	413	2	245	1.0e-39	158	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
638027943	365	28.69	1	342	1	345	2.0e-30	126	COG0644	Dehydrogenase (flavoprotein)	396
638027944	592	30.69	9	567	1	534	1.0e-75	278	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
638027945	85	31.94	3	73	9	80	1.0e-07	48	COG0236	Acyl carrier protein	80
638027946	210	39.16	29	193	5	169	2.0e-43	168	COG1755	Uncharacterized protein YpbQ, isoprenylcysteine carboxyl methyltransferase (ICMT) family	172
638027947	360	47.06	11	360	2	352	2.0e-100	359	COG3424	Predicted naringenin-chalcone synthase	356
638027951	356	41.6	3	351	2	349	1.0e-74	273	COG4148	ABC-type molybdate transport system, ATPase component	352
638027952	224	47.93	8	223	9	225	1.0e-53	203	COG4149	ABC-type molybdate transport system, permease component	225
638027953	252	43.72	4	248	12	258	4.0e-50	191	COG0725	ABC-type molybdate transport system, periplasmic component	258
638027954	169	36.04	45	155	16	126	2.0e-12	65.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
638027955	531	42.59	54	419	16	345	4.0e-64	239	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
638027956	292	29.41	84	252	17	181	3.0e-14	72.5	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
638027959	287	32.18	34	271	3	259	3.0e-27	115	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
638027961	184	25.33	1	150	24	173	4.0e-06	44.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638027963	483	31.04	1	483	1	499	5.0e-112	398	COG0442	Prolyl-tRNA synthetase	500
638027964	185	36.52	1	178	1	172	7.0e-27	113	COG1514	2'-5' RNA ligase	180
638027967	255	46.88	1	253	2	255	4.0e-68	251	COG4106	Trans-aconitate methyltransferase	257
638027969	246	55.32	12	245	2	236	2.0e-88	318	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
638027970	294	50.74	14	283	2	249	6.0e-88	317	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
638027971	330	41.72	1	315	8	311	2.0e-45	176	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
638027972	306	46.08	1	305	3	297	2.0e-51	196	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
638027973	401	35.62	44	401	2	365	2.0e-58	220	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
638027977	356	30.06	35	326	2	303	4.0e-34	139	COG0515	Serine/threonine protein kinase	384
638027979	607	58.21	1	602	4	577	0.0e+00	660	COG0443	Molecular chaperone DnaK (HSP70)	579
638027980	255	34.72	25	216	3	193	3.0e-36	145	COG0576	Molecular chaperone GrpE (heat shock protein)	193
638027987	3146	20.7	2160	2788	3	659	7.0e-21	98.4	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
638027989	260	26.02	36	231	2	180	8.0e-14	71.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638027996	462	30.92	9	158	1	151	1.0e-14	74.5	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
638027997	393	45.6	6	388	1	379	3.0e-96	345	COG1641	Uncharacterized conserved protein, DUF111 family	387
638027998	250	50.4	4	247	1	250	3.0e-69	255	COG1691	NCAIR mutase (PurE)-related protein	254
638027999	200	30.96	7	200	8	201	2.0e-19	89.2	COG1776	Chemotaxis protein CheY-P-specific phosphatase CheC	203
638028000	857	35.99	336	855	155	706	2.0e-111	397	COG0643	Chemotaxis protein histidine kinase CheA	716
638028002	140	32.59	1	128	18	151	3.0e-18	84.2	COG0835	Chemotaxis signal transduction protein	165
638028003	245	25.47	18	118	4	105	6.0e-06	44.9	COG2315	Predicted DNA-binding protein with ?double-wing? structural motif, MmcQ/YjbR family	118
638028004	413	29.43	29	395	60	406	5.0e-31	128	COG0840	Methyl-accepting chemotaxis protein	408
638028005	315	42.99	1	309	2	317	2.0e-75	275	COG0611	Thiamine monophosphate kinase	317
638028007	465	45.76	7	465	12	481	5.0e-120	424	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
638028010	502	35.06	138	483	6	335	1.0e-45	177	COG0642	Signal transduction histidine kinase	336
638028011	298	28.24	72	237	12	169	1.0e-10	60.7	COG2229	Signal recognition particle receptor subunit beta, a GTPase	187
638028012	178	24.52	36	178	19	173	9.0e-12	63.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
638028013	574	49	195	542	5	353	3.0e-105	376	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
638028014	369	52.74	6	352	5	351	5.0e-119	421	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
638028015	129	31.4	6	125	7	124	9.0e-12	62.6	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
638028016	187	19.21	8	184	5	163	7.0e-10	57.2	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
638028021	238	28.89	30	158	17	150	3.0e-10	59.1	COG4244	Uncharacterized membrane protein	160
638028022	260	47.04	1	251	1	253	7.0e-78	283	COG0024	Methionine aminopeptidase	255
638028024	761	23.02	106	735	28	587	9.0e-37	149	COG4206	Outer membrane cobalamin receptor protein	608
638028025	662	36.07	19	643	5	639	4.0e-118	419	COG1199	Rad3-related DNA helicase	654
638028030	238	30.7	1	212	3	215	2.0e-30	126	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
638028032	304	35.5	1	302	6	296	9.0e-53	200	COG1597	Diacylglycerol kinase family enzyme	301
638028034	343	41.76	4	342	3	342	3.0e-85	309	COG1420	Transcriptional regulator of heat shock response	346
638028035	312	27.02	33	312	7	289	9.0e-06	44.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
638028036	301	36.81	1	299	1	324	5.0e-47	181	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
638028039	297	37.37	1	294	1	297	6.0e-66	244	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
638028040	260	31.92	28	233	5	216	1.0e-40	160	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
638028042	671	33.52	313	656	113	452	2.0e-44	174	COG5002	Signal transduction histidine kinase	459
638028043	2478	29.75	1668	2018	8	336	4.0e-43	172	COG0642	Signal transduction histidine kinase	336
638028045	759	14.74	5	759	15	768	9.0e-07	49.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
638028052	300	30.6	21	299	1	260	3.0e-44	172	COG3358	Uncharacterized conserved protein, DUF1684 family	262
638028053	387	37.31	1	372	1	390	1.0e-62	233	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
638028054	256	39.53	6	254	4	250	3.0e-40	158	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638028055	389	24.74	162	351	27	210	6.0e-06	45.8	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
638028061	553	23.86	32	414	50	387	3.0e-27	117	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
638028067	211	35.26	11	200	1	180	7.0e-31	127	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638028070	301	60.6	5	297	2	302	3.0e-116	411	COG0408	Coproporphyrinogen III oxidase	303
638028073	268	30.95	1	250	1	241	5.0e-35	141	COG1647	Esterase/lipase	243
638028074	242	47.77	9	231	1	224	2.0e-74	272	COG1136	ABC-type lipoprotein export system, ATPase component	226
638028075	846	19.14	477	846	2	419	4.0e-20	94	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
638028075	846	24.94	20	387	26	406	3.0e-25	111	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
638028076	412	39.57	13	386	1	354	3.0e-79	289	COG5621	Predicted secreted hydrolase	354
638028079	496	56.05	1	496	1	493	0.0e+00	710	COG0554	Glycerol kinase	499
638028081	103	40.4	4	100	2	100	9.0e-20	88.4	COG2154	Pterin-4a-carbinolamine dehydratase	101
638028085	362	29.18	1	359	6	404	1.0e-38	154	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
638028086	216	25.12	10	205	4	198	2.0e-08	53.1	COG3806	Anti-sigma factor ChrR, cupin superfamily	216
638028087	280	40.78	34	276	30	271	8.0e-52	197	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
638028091	480	27.46	80	470	58	440	2.0e-51	197	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
638028092	239	20.92	1	238	3	218	2.0e-16	79.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
638028093	699	34.03	1	377	1	381	1.0e-52	201	COG0475	Kef-type K+ transport system, membrane component KefB	397
638028097	344	67.56	9	341	5	339	6.0e-128	450	COG1077	Actin-like ATPase involved in cell morphogenesis	342
638028099	337	38.48	5	336	1	325	1.0e-57	217	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
638028100	305	36.82	10	301	8	297	1.0e-36	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
638028103	307	43.58	1	296	1	294	1.0e-78	286	COG3781	Predicted membrane chloride channel, bestrophin family	306
638028106	430	32.86	9	352	12	327	5.0e-41	162	COG4748	Uncharacterized protein	365
638028107	342	24.1	60	319	36	309	3.0e-10	59.4	COG0385	Predicted Na+-dependent transporter	319
638028108	762	41.28	7	748	5	740	0.0e+00	548	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
638028110	351	40.73	1	351	2	350	1.0e-68	253	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
638028112	479	32.24	40	461	16	437	2.0e-45	177	COG0534	Na+-driven multidrug efflux pump	455
638028113	210	42.03	1	206	1	203	7.0e-46	177	COG0522	Ribosomal protein S4 or related protein	205
638028114	333	22.48	35	329	2	281	7.0e-13	68.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638028119	695	40.83	27	694	4	648	0.0e+00	663	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
638028121	243	43.27	33	237	18	220	1.0e-41	163	COG4340	Uncharacterized protein	226
638028122	344	26.78	3	283	1	284	3.0e-17	83	COG3594	Fucose 4-O-acetylase or related acetyltransferase	343
638028130	850	28.57	13	837	19	855	3.0e-115	409	COG0308	Aminopeptidase N	859
638028134	390	25.19	8	390	7	402	2.0e-25	110	COG1668	ABC-type Na+ efflux pump, permease component	407
638028135	245	51.03	1	243	1	243	2.0e-80	291	COG4555	ABC-type Na+ transport system, ATPase component NatA	245
638028138	130	57.52	3	115	2	114	7.0e-44	169	COG0853	Aspartate 1-decarboxylase	126
638028141	238	39.45	78	186	14	120	7.0e-08	51.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
638028150	195	24.62	6	193	1	198	6.0e-16	77.6	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
638028151	415	31.67	12	221	21	239	1.0e-24	108	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
638028153	876	15.97	134	845	2	756	1.0e-15	78.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
638028155	464	28.03	134	446	30	334	3.0e-35	143	COG0642	Signal transduction histidine kinase	336
638028159	630	24.64	2	278	1	267	1.0e-27	118	COG0388	Predicted amidohydrolase	274
638028159	630	30.6	327	552	5	224	3.0e-33	137	COG0171	NH3-dependent NAD+ synthetase	268
638028160	221	31.55	17	198	12	198	5.0e-21	94.6	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
638028166	406	24.88	120	318	38	240	5.0e-06	46.1	COG3063	Tfp pilus assembly protein PilF	250
638028167	219	36.11	1	214	2	217	7.0e-38	150	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
638028168	194	19.86	32	176	14	132	3.0e-06	45.2	COG0848	Biopolymer transport protein ExbD	137
638028170	245	28.87	32	225	18	209	1.0e-18	87	COG0811	Biopolymer transport protein ExbB/TolQ	216
638028172	407	51.47	85	219	1	136	5.0e-52	198	COG0229	Peptide methionine sulfoxide reductase MsrB	140
638028172	407	53.99	245	407	6	165	3.0e-65	242	COG0225	Peptide methionine sulfoxide reductase MsrA	174
638028176	120	42.52	1	118	3	127	3.0e-30	123	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
638028177	249	60.25	3	240	9	246	8.0e-89	320	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
638028180	374	26.75	53	370	79	401	7.0e-47	181	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
638028181	302	25.98	16	293	1	271	3.0e-12	65.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638028182	271	32.16	21	245	15	230	3.0e-31	128	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
638028183	259	34.87	7	256	6	251	1.0e-30	126	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638028184	279	26.21	155	253	25	127	2.0e-06	46.6	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
638028184	279	31.48	21	128	3	104	7.0e-13	67.9	COG1539	Dihydroneopterin aldolase	121
638028185	244	39.13	1	241	2	251	4.0e-37	148	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638028188	167	35.95	30	164	1	150	2.0e-19	88.4	COG0782	Transcription elongation factor, GreA/GreB family	151
638028189	224	34.04	2	224	1	235	3.0e-40	158	COG0412	Dienelactone hydrolase	236
638028203	543	33.33	340	502	33	189	3.0e-27	116	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
638028208	298	25.19	4	268	5	263	2.0e-18	86.9	COG1834	N-Dimethylarginine dimethylaminohydrolase	267
638028211	221	21.98	14	195	1	182	1.0e-06	47	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638028212	301	29.57	13	258	17	271	1.0e-30	127	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
638028213	529	34.04	21	475	3	443	5.0e-84	305	COG0166	Glucose-6-phosphate isomerase	446
638028214	256	45.31	3	252	1	250	1.0e-39	156	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638028216	664	35.84	16	664	18	699	0.0e+00	467	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
638028217	342	26.41	1	331	1	335	1.0e-31	130	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
638028218	445	38.67	1	427	2	437	1.0e-98	353	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
638028221	342	23.08	10	327	6	314	2.0e-23	103	COG1397	ADP-ribosylglycohydrolase	314
638028223	148	42.75	1	137	1	137	4.0e-30	123	COG1959	DNA-binding transcriptional regulator, IscR family	150
638028224	332	29.32	91	332	5	246	6.0e-28	118	COG1018	Ferredoxin-NADP reductase	266
638028224	332	34.21	14	84	20	95	7.0e-09	55.1	COG0633	Ferredoxin	102
638028225	126	34.48	6	117	6	117	7.0e-17	79.6	COG2346	Truncated hemoglobin YjbI	133
638028226	136	32.09	1	132	1	133	9.0e-23	99.2	COG0355	FoF1-type ATP synthase, epsilon subunit	135
638028228	481	73.01	7	481	2	468	0.0e+00	785	COG0055	FoF1-type ATP synthase, beta subunit	468
638028229	285	20.34	21	278	2	283	4.0e-18	85.5	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
638028230	294	46.92	5	294	1	287	5.0e-83	300	COG0224	FoF1-type ATP synthase, gamma subunit	287
638028232	225	38.78	25	215	23	216	1.0e-35	143	COG2949	Uncharacterized periplasmic protein SanA, affects membrane permeability for vancomycin	235
638028239	607	28.82	21	602	5	565	2.0e-79	290	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
638028243	591	23.82	210	590	33	406	8.0e-33	135	COG0840	Methyl-accepting chemotaxis protein	408
638028246	529	32.48	7	508	2	487	2.0e-76	280	COG1233	Phytoene dehydrogenase-related protein	487
638028247	574	41.67	324	574	94	336	6.0e-44	172	COG0642	Signal transduction histidine kinase	336
638028253	159	40.14	7	151	19	165	2.0e-24	105	COG0835	Chemotaxis signal transduction protein	165
638028254	569	36.9	8	272	1	265	4.0e-60	226	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
638028255	200	27.01	56	187	18	154	1.0e-12	66.5	COG0835	Chemotaxis signal transduction protein	165
638028256	547	29.31	140	545	18	406	6.0e-41	162	COG0840	Methyl-accepting chemotaxis protein	408
638028258	353	42.69	7	352	3	348	6.0e-80	291	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
638028260	595	45.34	1	391	5	396	5.0e-69	255	COG0475	Kef-type K+ transport system, membrane component KefB	397
638028261	501	30.99	252	491	101	336	3.0e-37	150	COG0642	Signal transduction histidine kinase	336
638028264	324	20.73	12	274	38	310	2.0e-14	73.6	COG3239	Fatty acid desaturase	343
638028265	348	44.9	7	348	2	344	1.0e-79	290	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
638028266	273	38.2	11	270	4	265	1.0e-47	183	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
638028267	788	31.34	313	660	3	326	2.0e-14	75.3	COG1413	HEAT repeat	335
638028268	821	23.94	177	531	54	405	2.0e-16	81.6	COG0840	Methyl-accepting chemotaxis protein	408
638028269	148	32.87	1	143	16	158	1.0e-25	109	COG0835	Chemotaxis signal transduction protein	165
638028270	683	30.49	1	660	4	705	1.0e-91	331	COG0643	Chemotaxis protein histidine kinase CheA	716
638028272	656	29.65	313	655	8	336	2.0e-37	151	COG0642	Signal transduction histidine kinase	336
638028273	149	30	12	148	5	139	1.0e-17	82.7	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
638028277	411	29.66	80	405	19	336	2.0e-40	160	COG0642	Signal transduction histidine kinase	336
638028278	300	31.98	66	292	39	281	5.0e-31	128	COG1408	Predicted phosphohydrolase, MPP superfamily	284
638028281	145	37.6	7	130	18	137	2.0e-08	52.3	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
638028284	436	24.92	138	436	41	334	7.0e-29	122	COG0642	Signal transduction histidine kinase	336
638028285	187	54.86	12	186	10	182	4.0e-51	194	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
638028287	287	23.91	41	214	43	225	1.0e-16	81.1	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
638028288	159	38.53	4	106	1	109	6.0e-13	67.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
638028291	468	31.28	16	445	37	469	1.0e-84	307	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638028292	725	45.41	1	207	1	199	4.0e-36	146	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638028292	725	47.04	321	605	4	285	4.0e-82	299	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
638028293	403	40.67	2	403	1	392	1.0e-80	293	COG0183	Acetyl-CoA acetyltransferase	392
638028298	419	25.07	57	409	4	336	8.0e-39	154	COG0642	Signal transduction histidine kinase	336
638028307	766	28.61	441	766	21	335	1.0e-34	141	COG0642	Signal transduction histidine kinase	336
638028315	460	26.54	87	329	23	282	6.0e-25	109	COG0714	MoxR-like ATPase	329
638028318	96	36.26	1	91	1	87	9.0e-14	68.3	COG1343	CRISPR/Cas system-associated endoribonuclease Cas2	89
638028319	342	35.4	4	341	2	327	5.0e-68	251	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
638028320	213	22.46	12	194	19	190	7.0e-21	94.3	COG1468	CRISPR/Cas system-associated exonuclease Cas4, RecB family	190
638028321	304	34.24	1	290	1	264	3.0e-37	149	COG3649	CRISPR/Cas system type I-B associated protein Csh2, Cas7 group, RAMP superfamily	283
638028325	237	38.3	1	235	1	227	1.0e-60	226	COG4947	Esterase/lipase superfamily enzyme	227
638028326	464	32.89	12	454	10	443	1.0e-54	207	COG0534	Na+-driven multidrug efflux pump	455
638028327	730	26.38	90	631	50	542	8.0e-45	175	COG4880	Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats	603
638028329	608	37.65	4	587	6	557	1.0e-115	410	COG0443	Molecular chaperone DnaK (HSP70)	579
638028330	182	33.89	1	180	2	178	6.0e-33	133	COG0712	FoF1-type ATP synthase, delta subunit	178
638028331	492	25.35	209	490	53	332	5.0e-25	109	COG0642	Signal transduction histidine kinase	336
638028332	552	67.25	38	547	1	503	0.0e+00	799	COG0056	FoF1-type ATP synthase, alpha subunit	504
638028339	236	26.77	7	199	3	199	1.0e-16	79.9	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
638028341	295	30.65	66	263	49	243	2.0e-30	126	COG1360	Flagellar motor protein MotB	244
638028344	397	27.65	2	396	7	439	2.0e-57	217	COG2067	Long-chain fatty acid transport protein	440
638028347	348	45.92	3	329	1	314	8.0e-83	300	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
638028353	164	28.14	1	162	30	193	7.0e-18	83.4	COG1515	Deoxyinosine 3'endonuclease (endonuclease V)	212
638028355	158	25.2	26	151	1	118	6.0e-13	66.9	COG4911	Uncharacterized protein	123
638028357	306	26.28	9	280	3	271	3.0e-26	112	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
638028361	458	32.79	6	427	7	437	2.0e-73	269	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
638028362	320	38.6	1	319	2	330	9.0e-63	234	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
638028364	218	56.98	41	212	1	170	2.0e-70	258	COG0225	Peptide methionine sulfoxide reductase MsrA	174
638028366	240	42.13	5	238	7	236	1.0e-62	233	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
638028368	127	45.92	2	99	6	103	9.0e-21	92.3	COG4323	Uncharacterized protein	105
638028370	116	47.66	8	114	10	116	1.0e-23	102	COG1733	DNA-binding transcriptional regulator, HxlR family	120
638028371	200	23.27	9	196	1	201	2.0e-19	88.9	COG0778	Nitroreductase	207
638028373	154	26.95	8	148	3	135	1.0e-21	96.1	COG0824	Acyl-CoA thioesterase FadM	137
638028376	486	39.16	15	485	2	456	7.0e-100	358	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
638028382	291	33.06	168	291	3	126	8.0e-22	98	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638028386	1021	30.14	66	336	2	281	5.0e-44	173	COG0515	Serine/threonine protein kinase	384
638028388	331	50	87	329	5	250	4.0e-87	315	COG0024	Methionine aminopeptidase	255
638028394	183	49.72	1	181	1	162	3.0e-59	220	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
638028397	283	40.65	1	279	7	316	1.0e-70	259	COG0627	S-formylglutathione hydrolase FrmB	316
638028398	369	72.36	1	369	1	366	0.0e+00	564	COG1062	Zn-dependent alcohol dehydrogenase	366
638028399	91	51.11	1	90	1	89	7.0e-19	85.7	COG1937	DNA-binding transcriptional regulator, FrmR family	89
638028407	346	34.82	101	343	24	264	8.0e-41	161	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
638028408	644	32.31	13	636	25	674	3.0e-127	449	COG0339	Zn-dependent oligopeptidase	683
638028413	276	41.7	65	276	15	236	5.0e-39	154	COG0412	Dienelactone hydrolase	236
638028414	259	44.95	40	235	7	204	1.0e-42	167	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
638028418	344	30.77	64	299	9	254	5.0e-33	135	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
638028419	557	34.17	10	557	9	539	3.0e-55	209	COG1178	ABC-type Fe3+ transport system, permease component	540
638028423	484	33.94	47	484	15	450	6.0e-68	252	COG0534	Na+-driven multidrug efflux pump	455
638028424	353	37.33	185	334	1	149	2.0e-26	113	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
638028426	415	19.53	161	370	31	218	3.0e-10	60.3	COG3591	V8-like Glu-specific endopeptidase	251
638028427	533	32.02	204	533	21	332	5.0e-40	159	COG0642	Signal transduction histidine kinase	336
638028428	376	25.63	19	365	28	365	6.0e-34	138	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
638028436	356	28.84	17	328	3	318	7.0e-46	177	COG5351	Uncharacterized protein	367
638028442	174	47.2	1	161	1	160	2.0e-37	148	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
638028443	635	28.19	140	635	36	588	1.0e-60	228	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
638028447	477	49.68	19	477	1	460	0.0e+00	467	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638028448	225	48.17	5	220	1	218	1.0e-66	245	COG1136	ABC-type lipoprotein export system, ATPase component	226
638028449	238	50.44	14	237	1	226	2.0e-76	278	COG1136	ABC-type lipoprotein export system, ATPase component	226
638028450	809	19.86	420	809	9	419	5.0e-19	90.2	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
638028451	414	23.13	4	305	5	288	4.0e-15	76.5	COG1566	Multidrug resistance efflux pump	352
638028452	519	42.99	4	513	12	525	4.0e-120	425	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
638028453	514	30.08	249	481	4	246	3.0e-24	106	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
638028455	183	42.08	1	182	1	183	2.0e-52	198	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
638028456	398	30	260	397	4	134	5.0e-17	82.3	COG1765	Uncharacterized OsmC-related protein	137
638028457	178	29.03	43	164	2	125	2.0e-13	69.2	COG1371	SHS2 domain protein implicated in nucleic acid metabolism	137
638028458	230	26.27	12	223	3	236	4.0e-09	55	COG0412	Dienelactone hydrolase	236
638028459	227	42.66	1	215	2	219	1.0e-36	146	COG1926	Predicted phosphoribosyltransferase	220
638028460	301	42.09	7	300	6	301	2.0e-83	302	COG0462	Phosphoribosylpyrophosphate synthetase	314
638028461	250	37.85	1	247	3	253	1.0e-46	179	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638028462	917	26.96	47	896	8	858	3.0e-102	366	COG0308	Aminopeptidase N	859
638028463	361	35.05	57	344	23	306	3.0e-47	182	COG1560	Lauroyl/myristoyl acyltransferase	308
638028464	409	33.51	23	408	4	359	7.0e-70	258	COG0787	Alanine racemase	360
638028466	992	27.8	81	350	2	290	4.0e-35	143	COG0515	Serine/threonine protein kinase	384
638028468	443	22	313	442	5	154	2.0e-09	57.3	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
638028469	338	48.21	1	332	1	324	2.0e-91	329	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
638028470	448	40.93	7	405	13	405	2.0e-92	333	COG1488	Nicotinic acid phosphoribosyltransferase	405
638028475	741	27.75	21	382	4	385	1.0e-36	148	COG1680	CubicO group peptidase, beta-lactamase class C family	390
638028480	515	45.95	132	514	124	499	5.0e-114	405	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
638028486	352	27.1	13	336	21	369	7.0e-14	71.8	COG4671	Predicted glycosyl transferase	400
638028490	413	24.62	9	397	3	379	5.0e-29	122	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638028491	397	26.61	6	392	2	378	7.0e-32	131	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638028493	354	16.42	56	323	8	186	6.0e-06	45.6	COG1335	Nicotinamidase-related amidase	205
638028496	229	39.73	4	145	3	144	3.0e-26	112	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
638028497	342	23.19	62	316	60	279	7.0e-12	65	COG1597	Diacylglycerol kinase family enzyme	301
638028498	334	34.68	6	252	5	251	1.0e-50	193	COG0300	Short-chain dehydrogenase	265
638028507	248	43.55	1	248	1	242	1.0e-41	163	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
638028509	323	29.87	247	316	14	89	4.0e-07	49.3	COG0633	Ferredoxin	102
638028509	323	36.16	1	263	2	266	1.0e-51	196	COG1018	Ferredoxin-NADP reductase	266
638028510	1379	25.64	37	672	10	648	9.0e-52	199	COG3292	Periplasmic ligand-binding sensor domain	671
638028512	781	25.51	15	336	2	327	5.0e-40	159	COG0515	Serine/threonine protein kinase	384
638028515	152	28.83	35	144	26	135	4.0e-08	51.1	COG5502	Uncharacterized conserved protein, DUF2267 family	135
638028517	387	30.37	5	345	1	327	4.0e-46	179	COG1858	Cytochrome c peroxidase	364
638028518	176	29.94	15	173	16	182	1.0e-16	79.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638028529	337	55.52	1	332	1	338	3.0e-121	428	COG3839	ABC-type sugar transport system, ATPase component	338
638028530	265	45.53	6	250	1	246	9.0e-74	270	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
638028535	266	30.38	2	259	13	267	2.0e-25	109	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
638028536	275	27.56	1	265	2	281	6.0e-26	111	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638028542	488	25	67	480	43	439	2.0e-24	107	COG1538	Outer membrane protein TolC	457
638028543	385	29.3	1	363	2	369	1.0e-22	100	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
638028544	1040	48.45	1	1027	1	1008	0.0e+00	969	COG0841	Multidrug efflux pump subunit AcrB	1009
638028545	643	25.08	341	622	2	293	1.0e-25	111	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
638028546	322	33.54	1	321	1	323	3.0e-51	195	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
638028548	275	31.64	13	265	8	251	2.0e-18	86.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638028555	1208	28.04	58	309	2	277	1.0e-30	129	COG0515	Serine/threonine protein kinase	384
638028556	222	38.1	14	221	4	209	3.0e-39	155	COG3932	Uncharacterized conserved protein	209
638028563	97	34.62	6	81	1	78	6.0e-09	52.6	COG1343	CRISPR/Cas system-associated endoribonuclease Cas2	89
638028564	568	22.46	40	211	24	190	2.0e-08	54.6	COG1468	CRISPR/Cas system-associated exonuclease Cas4, RecB family	190
638028564	568	32.31	235	557	8	317	7.0e-43	168	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
638028573	619	25.57	29	303	2	289	3.0e-24	107	COG0515	Serine/threonine protein kinase	384
638028574	396	35.5	44	379	4	341	1.0e-41	164	COG0628	Predicted PurR-regulated permease PerM	355
638028577	361	40.64	21	270	1	235	3.0e-49	189	COG4279	Uncharacterized conserved protein, contains Zn finger domain	266
638028578	1093	31.41	340	1059	76	866	1.0e-107	384	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
638028583	317	31.21	2	308	1	295	1.0e-46	180	COG1336	CRISPR/Cas system CMR subunit Cmr4, Cas7 group, RAMP superfamily	298
638028586	496	20	26	433	7	343	2.0e-17	84	COG1367	CRISPR/Cas system CMR-associated protein Cmr1, group 7 of RAMP superfamily	393
638028593	182	30.22	1	180	6	182	8.0e-18	83.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638028597	269	45.11	10	268	16	281	5.0e-59	221	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
638028598	292	46.94	3	292	1	294	6.0e-69	254	COG1175	ABC-type sugar transport system, permease component	295
638028599	426	27.13	1	419	2	427	6.0e-48	185	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
638028602	429	32.68	23	428	17	411	3.0e-66	246	COG2124	Cytochrome P450	411
638028603	350	19.94	1	350	1	342	2.0e-20	93.6	COG3239	Fatty acid desaturase	343
638028606	200	30.29	9	170	14	186	2.0e-10	59.3	COG0558	Phosphatidylglycerophosphate synthase	192
638028608	439	32.58	265	434	67	243	7.0e-23	101	COG1651	Protein-disulfide isomerase	244
638028611	459	23.95	134	436	35	295	5.0e-15	76.1	COG3491	Isopenicillin N synthase and related dioxygenases	322
638028612	411	40.2	103	396	77	368	2.0e-73	269	COG2821	Membrane-bound lytic murein transglycosylase	373
638028614	273	30.92	3	239	2	241	6.0e-31	128	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638028615	558	25.45	78	457	24	393	2.0e-43	170	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638028616	294	29.29	3	294	1	297	3.0e-27	115	COG0583	DNA-binding transcriptional regulator, LysR family	297
638028617	313	20.47	97	311	30	210	1.0e-10	61	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
638028618	328	26.59	10	327	9	309	1.0e-28	120	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
638028619	271	30.63	12	260	14	282	1.0e-27	117	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638028620	216	25.77	18	211	4	195	1.0e-08	53.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638028622	535	22.46	13	323	6	320	2.0e-08	54.6	COG4219	Signal transducer regulating beta-lactamase production, contains  metallopeptidase domain	337
638028623	133	32.77	14	132	4	122	3.0e-22	97.2	COG3682	Predicted transcriptional regulator	123
638028624	526	30.29	12	387	3	378	4.0e-54	206	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
638028626	301	31.89	5	301	2	295	3.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
638028627	349	42.41	1	346	1	339	2.0e-118	418	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
638028629	410	27.69	15	398	8	377	6.0e-25	108	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
638028630	204	39.88	25	197	5	176	1.0e-21	96.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638028632	601	23	60	554	18	497	3.0e-11	63.9	COG1404	Serine protease, subtilisin family	508
638028633	565	44.32	23	552	1	525	6.0e-122	431	COG0578	Glycerol-3-phosphate dehydrogenase	532
638028635	803	18.67	134	770	10	592	1.0e-14	75.8	COG4206	Outer membrane cobalamin receptor protein	608
638028643	66	40.91	3	66	7	72	4.0e-06	43	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
638028651	168	41.92	1	161	2	168	2.0e-40	158	COG0242	Peptide deformylase	168
638028657	370	30.43	4	369	3	321	9.0e-45	174	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
638028660	288	25.61	1	279	5	274	4.0e-32	132	COG0714	MoxR-like ATPase	329
638028661	402	41.6	1	392	1	393	2.0e-80	293	COG3825	Uncharacterized conserved protein,  contains von Willebrand factor type A (vWA) domain	393
638028662	687	54.33	2	681	1	663	0.0e+00	920	COG0021	Transketolase	663
638028665	545	24.09	223	541	22	324	2.0e-17	83.9	COG5276	Uncharacterized conserved protein	370
638028666	673	27.43	6	179	3	170	1.0e-12	68.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638028666	673	31.84	284	673	14	432	4.0e-63	236	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
638028667	842	32.64	199	574	87	446	3.0e-50	193	COG5002	Signal transduction histidine kinase	459
638028671	543	37.65	286	531	94	330	2.0e-38	153	COG0642	Signal transduction histidine kinase	336
638028673	390	27.27	21	310	2	294	6.0e-32	132	COG0515	Serine/threonine protein kinase	384
638028674	458	24.34	29	321	2	277	9.0e-22	98.7	COG0515	Serine/threonine protein kinase	384
638028680	406	44.55	8	406	2	399	0.0e+00	487	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
638028681	314	23.15	9	313	3	295	1.0e-14	74.2	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
638028682	374	25.18	14	286	3	245	1.0e-25	110	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
638028683	380	39.83	237	352	2	116	3.0e-18	86.7	COG0517	CBS domain	117
638028684	272	23.72	4	150	10	164	1.0e-10	61	COG0723	Rieske Fe-S protein	177
638028684	272	27.27	184	268	17	103	2.0e-07	50	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
638028685	192	28.47	4	142	2	139	5.0e-07	48	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
638028690	364	38.81	194	363	4	203	5.0e-32	132	COG3179	Predicted chitinase	206
638028691	259	27.92	61	256	15	205	6.0e-30	124	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
638028697	453	27.92	146	298	8	152	3.0e-09	57.3	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
638028699	497	32.35	260	497	7	214	6.0e-32	132	COG2114	Adenylate cyclase, class 3	227
638028701	999	37.06	717	999	53	331	2.0e-39	158	COG0642	Signal transduction histidine kinase	336
638028703	291	53.44	21	282	3	262	5.0e-86	311	COG3483	Tryptophan 2,3-dioxygenase (vermilion)	262
638028707	312	30.89	1	307	1	324	1.0e-37	150	COG0506	Proline dehydrogenase	391
638028708	597	30.86	4	586	15	605	5.0e-105	375	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
638028714	208	42.86	14	199	6	188	2.0e-29	122	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
638028715	416	41.63	3	406	6	403	1.0e-88	320	COG0303	Molybdopterin biosynthesis enzyme	404
638028716	466	39.88	5	165	3	161	6.0e-26	112	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
638028716	466	40.36	183	462	6	266	1.0e-61	230	COG1526	Formate dehydrogenase assembly factor FdhD	266
638028717	494	45.49	266	493	3	225	3.0e-64	239	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
638028718	490	20.17	1	465	6	474	9.0e-18	85.2	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
638028719	219	32.76	51	219	36	204	1.0e-22	99.8	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
638028723	507	20.56	48	488	17	458	6.0e-19	89.4	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
638028724	414	24.08	1	393	6	398	1.0e-29	124	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
638028732	139	32.97	1	85	1	91	2.0e-09	55.1	COG3293	Transposase	124
638028734	700	25.87	297	629	1	339	3.0e-24	107	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
638028736	265	28.17	5	264	1	282	6.0e-24	104	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638028737	446	27.08	77	441	61	443	1.0e-20	94.4	COG1538	Outer membrane protein TolC	457
638028738	1057	39.86	1	1019	1	1021	0.0e+00	922	COG3696	Cu/Ag efflux pump CusA	1027
638028739	367	31.43	30	367	22	367	2.0e-14	73.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
638028740	501	30.27	132	496	1	333	6.0e-35	142	COG0642	Signal transduction histidine kinase	336
638028741	451	43.97	6	447	5	451	3.0e-122	432	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638028742	484	29	147	473	62	381	2.0e-31	130	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638028744	439	40.42	6	438	29	451	2.0e-97	349	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
638028746	412	32.09	130	411	88	378	4.0e-34	139	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638028749	337	28.97	5	242	1	247	1.0e-22	100	COG1216	Glycosyltransferase, GT2 family	305
638028752	271	40	15	262	4	249	3.0e-55	208	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
638028755	212	28.49	38	212	6	181	2.0e-14	72.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638028763	322	45.9	1	318	2	329	9.0e-79	287	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
638028765	588	35.25	23	453	8	435	3.0e-58	220	COG0038	H+/Cl- antiporter ClcA	443
638028771	448	34.19	167	448	28	314	9.0e-39	154	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
638028772	341	56.63	30	338	13	319	7.0e-99	353	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
638028774	150	34.38	17	144	8	135	6.0e-22	96.9	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
638028775	296	37.55	38	289	4	240	4.0e-35	141	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
638028776	283	43.25	23	272	3	253	8.0e-60	223	COG1192	Cellulose biosynthesis protein BcsQ	259
638028792	217	36.28	6	217	1	213	4.0e-39	154	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
638028793	615	52.31	1	603	1	617	0.0e+00	773	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
638028794	420	22.68	36	401	34	394	7.0e-18	85.3	COG2814	Predicted arabinose efflux permease, MFS family	394
638028795	259	25.35	5	256	2	282	4.0e-18	85.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638028796	953	29.55	58	471	7	427	7.0e-60	226	COG0612	Predicted Zn-dependent peptidase	438
638028797	680	33.33	345	635	28	308	1.0e-51	198	COG0616	Periplasmic serine protease, ClpP class	317
638028800	108	34.41	8	98	18	110	1.0e-09	55.2	COG0640	DNA-binding transcriptional regulator, ArsR family	110
638028801	146	28.47	5	137	9	149	1.0e-10	58.9	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
638028804	219	30.12	42	204	31	194	9.0e-12	64.1	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
638028805	442	40.57	2	442	1	454	9.0e-107	380	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
638028808	603	36.48	280	588	5	304	3.0e-54	206	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
638028809	72	59.15	2	72	4	74	5.0e-22	95.8	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
638028810	140	37.1	18	139	1	117	1.0e-12	65.7	COG0594	RNase P protein component	117
