gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
637678430	465	45.51	5	461	1	408	1.0e-125	443	COG0593	Chromosomal replication initiation ATPase DnaA	408
637678431	368	43.17	4	368	3	364	2.0e-85	309	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
637678432	834	59.45	16	598	3	559	0.0e+00	842	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
637678433	149	45.93	12	144	2	136	2.0e-35	141	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
637678434	150	58.9	1	146	1	145	4.0e-50	190	COG1490	D-Tyr-tRNAtyr deacylase	145
637678435	271	26.8	5	251	1	226	4.0e-26	112	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
637678436	379	47.26	9	342	16	360	3.0e-95	342	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
637678438	346	34.39	2	335	1	335	2.0e-56	213	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
637678439	339	38.6	19	335	1	314	4.0e-57	215	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
637678442	540	40.96	1	540	3	530	0.0e+00	581	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
637678445	235	40.59	1	231	3	241	3.0e-55	208	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
637678446	304	32.77	1	294	1	289	5.0e-38	151	COG0583	DNA-binding transcriptional regulator, LysR family	297
637678447	848	31.97	12	644	1	569	2.0e-130	460	COG0550	DNA topoisomerase IA	570
637678448	358	44.63	4	357	3	350	1.0e-97	350	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
637678450	167	52.98	1	164	1	168	1.0e-57	215	COG0242	Peptide deformylase	168
637678451	307	51.63	1	301	2	307	6.0e-105	374	COG0223	Methionyl-tRNA formyltransferase	307
637678452	280	35.11	7	280	33	297	1.0e-40	160	COG0501	Zn-dependent protease with chaperone function	302
637678453	116	47.06	1	102	1	98	3.0e-25	106	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
637678454	193	37.56	2	188	1	183	1.0e-27	116	COG0693	Putative intracellular protease/amidase	188
637678455	131	37.4	3	125	15	126	6.0e-22	96.5	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
637678457	419	37.5	94	417	3	353	2.0e-73	269	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
637678459	718	34.2	1	708	6	712	0.0e+00	486	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
637678460	421	30.59	1	413	4	456	4.0e-64	239	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
637678461	355	53.12	1	351	2	350	9.0e-122	430	COG0407	Uroporphyrinogen-III decarboxylase	352
637678462	666	41.28	7	666	1	730	0.0e+00	619	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
637678465	234	36.19	4	213	4	210	2.0e-48	185	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
637678466	297	37.58	1	296	7	305	2.0e-48	186	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
637678471	120	37.39	3	117	5	116	9.0e-23	98.9	COG3450	Predicted enzyme of the cupin superfamily	116
637678472	238	23.89	5	226	25	226	2.0e-16	80.1	COG0860	N-acetylmuramoyl-L-alanine amidase	231
637678473	337	32.75	1	337	1	286	1.0e-68	253	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
637678474	603	41.03	30	588	16	594	0.0e+00	514	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
637678475	1220	55.7	329	1190	1	842	0.0e+00	1081	COG1410	Methionine synthase I, cobalamin-binding domain	842
637678475	1220	56.4	4	328	3	311	7.0e-113	402	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
637678477	132	26.36	1	129	1	106	2.0e-11	61.5	COG0607	Rhodanese-related sulfurtransferase	110
637678478	400	22.47	36	391	38	377	6.0e-20	92.2	COG2814	Predicted arabinose efflux permease, MFS family	394
637678479	498	56.24	15	497	1	489	0.0e+00	577	COG0606	Predicted ATPase with chaperone activity	490
637678480	80	48.05	1	74	10	86	6.0e-14	69.3	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
637678482	112	75	1	112	1	112	2.0e-39	154	COG0347	Nitrogen regulatory protein PII	112
637678483	499	55.07	67	499	2	404	5.0e-113	401	COG0004	Ammonia channel protein AmtB	409
637678484	180	19.31	3	163	1	202	1.0e-10	59.8	COG1335	Nicotinamidase-related amidase	205
637678485	289	55.94	4	289	3	287	1.0e-117	415	COG0788	Formyltetrahydrofolate hydrolase	287
637678486	203	24.15	1	192	5	208	4.0e-18	84.6	COG0560	Phosphoserine phosphatase	212
637678488	287	23.78	1	268	4	284	9.0e-21	94.2	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
637678489	104	37.5	1	104	1	104	5.0e-19	86.1	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
637678490	635	44.36	1	522	3	530	0.0e+00	522	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
637678492	404	28.96	28	355	25	344	1.0e-49	191	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
637678493	345	45.45	1	339	5	339	1.0e-99	356	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
637678494	166	35.44	5	157	3	159	1.0e-26	112	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
637678501	210	33.33	11	205	3	206	1.0e-32	133	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
637678502	203	48.28	1	203	1	190	6.0e-68	250	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
637678503	176	31.61	13	167	8	161	3.0e-17	81.5	COG4769	Uncharacterized membrane protein	181
637678504	124	28.21	7	117	8	122	4.0e-15	73.4	COG5341	Uncharacterized protein	132
637678505	285	50.88	5	283	1	284	5.0e-97	347	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
637678506	389	49.87	12	388	10	389	6.0e-121	427	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
637678507	257	24.31	22	233	43	254	7.0e-23	101	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
637678508	219	37.68	18	218	43	247	6.0e-46	177	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
637678509	1201	32.42	797	1052	1	222	2.0e-44	175	COG2049	Allophanate hydrolase subunit 1	223
637678509	1201	41.32	448	763	1	306	2.0e-84	307	COG1984	Allophanate hydrolase subunit 2	314
637678510	600	34.91	1	444	2	465	1.0e-82	301	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
637678511	151	41.04	8	140	2	135	1.0e-28	119	COG0864	Metal-responsive transcriptional regulator, contains CopG/Arc/MetJ DNA-binding domain	136
637678512	453	34.78	2	449	1	440	2.0e-96	346	COG0174	Glutamine synthetase	443
637678513	252	37.96	1	236	1	243	5.0e-39	154	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
637678514	307	50.4	31	282	2	246	4.0e-92	331	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
637678515	318	34.67	87	311	36	253	3.0e-38	152	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
637678516	332	27.48	14	268	12	271	1.0e-27	117	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
637678518	304	25.58	15	224	20	231	1.0e-19	90.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
637678522	227	27.56	5	225	2	251	4.0e-22	98.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
637678524	666	55.66	1	663	1	644	0.0e+00	837	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
637678525	261	38.08	1	258	3	257	2.0e-41	162	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
637678526	205	47.6	1	203	1	208	1.0e-61	229	COG2808	Predicted FMN-binding regulatory protein PaiB	209
637678527	535	46.08	12	535	1	526	0.0e+00	651	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
637678528	199	39.09	1	193	14	204	4.0e-40	157	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
637678529	201	40.7	1	199	6	203	2.0e-46	178	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
637678530	273	25.49	12	145	6	158	7.0e-06	44.6	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
637678531	378	47.92	1	375	3	386	3.0e-99	355	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
637678532	304	21.99	13	294	18	281	7.0e-06	44.9	COG5006	Threonine/homoserine efflux transporter RhtA	292
637678533	396	40.59	3	393	2	388	7.0e-74	271	COG0183	Acetyl-CoA acetyltransferase	392
637678534	387	40.1	175	367	2	198	4.0e-56	212	COG0288	Carbonic anhydrase	207
637678535	390	43.15	6	390	1	391	2.0e-88	319	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
637678536	148	28.78	7	145	4	140	3.0e-17	80.8	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
637678537	130	29.27	8	128	1	121	3.0e-12	64.4	COG0789	DNA-binding transcriptional regulator, MerR family	124
637678538	341	22.14	16	275	5	234	3.0e-15	76	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
637678539	611	52.64	149	602	7	444	0.0e+00	541	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
637678541	415	22.55	126	410	66	365	2.0e-17	83.9	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
637678542	151	32.03	11	138	7	131	1.0e-16	78.8	COG3154	Predicted lipid carrier protein YhbT, SCP2 domain	168
637678543	300	26.07	2	286	1	299	3.0e-41	162	COG0826	Collagenase-like protease, PrtC family	347
637678544	335	35.91	5	335	7	312	3.0e-71	262	COG0826	Collagenase-like protease, PrtC family	347
637678547	370	44.93	19	370	14	377	2.0e-76	279	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
637678548	636	34.22	4	624	3	599	0.0e+00	462	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
637678549	173	33.53	8	171	1	167	2.0e-18	85.2	COG2891	Cell shape-determining protein MreD	167
637678550	311	32.75	10	291	1	284	6.0e-50	191	COG1792	Cell shape-determining protein MreC	284
637678551	347	66.57	5	346	1	341	2.0e-129	455	COG1077	Actin-like ATPase involved in cell morphogenesis	342
637678552	95	45.26	1	95	1	95	2.0e-22	97.6	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
637678553	485	53.46	1	482	4	475	0.0e+00	514	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
637678555	484	57.53	1	483	3	481	0.0e+00	689	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
637678557	213	36.97	2	209	1	201	1.0e-46	179	COG0461	Orotate phosphoribosyltransferase	201
637678558	259	42.86	2	258	1	261	1.0e-77	283	COG0708	Exonuclease III	261
637678559	104	42.31	1	104	1	104	8.0e-19	85.3	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
637678560	135	22.31	1	129	1	129	6.0e-08	49.9	COG5393	Uncharacterized membrane protein YqjE	131
637678565	374	53.12	4	372	9	368	1.0e-128	453	COG2021	Homoserine acetyltransferase	368
637678567	679	23.56	1	546	1	570	1.0e-33	138	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
637678569	301	25	53	293	65	317	1.0e-19	90.7	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
637678570	197	38.69	1	197	11	207	4.0e-38	150	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
637678572	263	28.41	2	261	49	312	6.0e-33	134	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
637678573	300	31.63	11	290	20	312	1.0e-36	146	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
637678574	330	30.14	1	328	5	352	1.0e-49	190	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
637678575	304	45.19	9	302	4	315	1.0e-71	263	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
637678576	324	28.64	89	294	1	207	2.0e-26	113	COG0778	Nitroreductase	207
637678579	487	53.4	5	487	3	486	0.0e+00	607	COG1492	Cobyric acid synthase	486
637678582	188	53.04	4	184	1	174	3.0e-54	204	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
637678583	348	38.95	6	348	10	337	3.0e-69	255	COG2038	NaMN:DMB phosphoribosyltransferase	347
637678584	256	33.89	9	247	5	239	8.0e-35	140	COG0368	Cobalamin synthase	246
637678586	185	34.41	15	183	2	187	2.0e-23	102	COG0406	Broad specificity phosphatase PhoE	208
637678587	367	32.76	19	365	1	330	1.0e-55	210	COG0859	ADP-heptose:LPS heptosyltransferase	334
637678588	381	25.51	1	381	1	380	5.0e-31	128	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
637678589	585	40.94	8	581	1	567	0.0e+00	479	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
637678590	361	27.46	1	361	3	381	5.0e-34	138	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
637678591	276	21.57	7	245	1	244	4.0e-13	68.9	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
637678592	382	26.14	35	378	1	331	2.0e-36	146	COG0859	ADP-heptose:LPS heptosyltransferase	334
637678593	398	30.95	53	398	40	379	4.0e-36	145	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
637678594	381	25.14	28	370	3	330	4.0e-34	139	COG0859	ADP-heptose:LPS heptosyltransferase	334
637678595	379	26.98	43	379	51	381	5.0e-31	128	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
637678596	440	19.91	16	437	22	424	5.0e-08	52.8	COG3307	O-antigen ligase	424
637678597	319	28.03	1	316	2	329	6.0e-33	135	COG0859	ADP-heptose:LPS heptosyltransferase	334
637678598	906	42.23	1	287	10	305	1.0e-73	271	COG0258	5'-3' exonuclease	310
637678598	906	56.81	307	906	1	593	0.0e+00	774	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
637678599	242	41.3	44	224	13	196	2.0e-45	176	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
637678601	308	34.92	1	300	5	318	3.0e-45	175	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
637678602	248	21.9	27	247	41	282	3.0e-06	45.7	COG5473	Uncharacterized membrane protein	290
637678604	217	38.68	5	215	5	196	4.0e-46	177	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
637678605	121	47.75	1	111	1	111	4.0e-31	126	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
637678606	156	47.74	1	154	1	155	1.0e-46	179	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
637678607	201	45.05	1	201	3	192	2.0e-56	212	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
637678611	257	40.86	1	254	3	257	4.0e-57	214	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
637678612	651	36.58	78	625	1	522	0.0e+00	465	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
637678613	369	23.55	1	334	8	356	3.0e-13	69.8	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
637678614	423	43.01	1	370	3	345	7.0e-104	371	COG0826	Collagenase-like protease, PrtC family	347
637678615	483	47.2	3	483	2	483	0.0e+00	493	COG1530	Ribonuclease G or E	487
637678616	291	38.84	52	288	2	232	4.0e-51	194	COG0412	Dienelactone hydrolase	236
637678621	274	40.29	1	274	13	288	3.0e-68	252	COG0685	5,10-methylenetetrahydrofolate reductase	291
637678622	273	49.8	29	273	4	242	2.0e-68	252	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
637678623	115	50	1	115	1	116	1.0e-13	68.6	COG1950	Uncharacterized membrane protein YvlD, DUF360 family	120
637678624	470	55.41	4	462	2	420	0.0e+00	626	COG0499	S-adenosylhomocysteine hydrolase	420
637678625	401	37.5	30	353	1	344	2.0e-71	263	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
637678626	387	70.62	1	387	2	388	0.0e+00	667	COG0192	S-adenosylmethionine synthetase	388
637678627	280	36.81	2	280	22	308	3.0e-53	202	COG1560	Lauroyl/myristoyl acyltransferase	308
637678628	291	46.62	1	291	13	308	1.0e-76	280	COG1560	Lauroyl/myristoyl acyltransferase	308
637678629	168	22	3	145	8	151	2.0e-09	55.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
637678630	276	53.28	3	276	1	272	2.0e-95	342	COG0253	Diaminopimelate epimerase	272
637678631	223	28.11	1	217	1	215	6.0e-37	147	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
637678632	295	56.27	4	295	10	299	4.0e-95	341	COG4973	Site-specific recombinase XerC	299
637678634	396	44.16	4	396	1	393	6.0e-110	391	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
637678637	298	24.66	10	297	22	297	2.0e-25	110	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
637678638	189	31.47	12	183	16	212	2.0e-27	116	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
637678639	254	24.21	4	253	12	263	2.0e-13	70.1	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
637678641	178	69.89	3	178	1	176	3.0e-75	274	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
637678642	446	68.01	1	446	1	444	0.0e+00	671	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
637678643	295	27.96	10	295	5	308	9.0e-24	104	COG0679	Predicted permease	311
637678644	122	55.56	1	90	9	98	1.0e-22	98.5	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
637678645	420	47.25	1	394	1	394	8.0e-118	417	COG0019	Diaminopimelate decarboxylase	394
637678646	105	35.58	1	102	1	103	1.0e-21	94.9	COG1965	Iron-binding protein CyaY, frataxin homolog	106
637678647	771	46.07	8	768	2	784	0.0e+00	853	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
637678648	361	42.94	6	359	2	354	2.0e-89	323	COG4972	Tfp pilus assembly protein, ATPase PilM	354
637678649	189	41.88	1	160	4	163	6.0e-33	133	COG3166	Tfp pilus assembly protein PilN	206
637678650	227	42.5	26	223	14	210	1.0e-49	189	COG3167	Tfp pilus assembly protein PilO	211
637678651	181	30.68	1	176	1	169	4.0e-32	130	COG3168	Tfp pilus assembly protein PilP	170
637678652	715	30.73	26	710	21	709	6.0e-99	355	COG4796	Type II secretory pathway, component HofQ	709
637678653	183	51.18	16	182	3	172	8.0e-53	199	COG0703	Shikimate kinase	172
637678654	364	60.22	5	360	1	355	0.0e+00	478	COG0337	3-dehydroquinate synthetase	360
637678655	1544	57.67	715	1225	3	485	0.0e+00	655	COG0069	Glutamate synthase domain 2	485
637678656	488	41.68	23	485	2	455	0.0e+00	482	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
637678658	452	56.77	1	452	3	460	0.0e+00	624	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
637678660	683	36.1	1	677	1	692	0.0e+00	544	COG0480	Translation elongation factor EF-G, a GTPase	697
637678661	1214	32.34	469	801	3	327	1.0e-44	175	COG0642	Signal transduction histidine kinase	336
637678662	243	42.22	10	228	3	225	6.0e-52	197	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
637678663	673	26.46	289	540	95	335	5.0e-27	116	COG0642	Signal transduction histidine kinase	336
637678664	545	35.83	18	536	10	523	3.0e-115	409	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
637678665	592	32.55	36	454	7	391	2.0e-67	250	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
637678666	547	28.05	464	544	23	96	9.0e-06	45.7	COG2440	Ferredoxin-like protein FixX	99
637678666	547	30.97	10	460	2	396	3.0e-73	270	COG0644	Dehydrogenase (flavoprotein)	396
637678667	211	23.83	11	201	15	206	9.0e-13	67.2	COG1584	Succinate-acetate transporter protein	207
637678668	355	35.56	160	335	16	181	2.0e-31	129	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
637678669	360	48.06	28	344	49	383	6.0e-103	367	COG1219	ATP-dependent protease Clp, ATPase subunit	408
637678670	738	32.27	269	575	28	327	5.0e-42	166	COG0642	Signal transduction histidine kinase	336
637678671	546	41.97	13	536	4	499	4.0e-123	435	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
637678672	296	25.69	6	288	1	285	9.0e-17	81.1	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
637678675	412	29.71	34	382	1	255	1.0e-33	137	COG0584	Glycerophosphoryl diester phosphodiesterase	257
637678676	252	47.7	1	234	7	245	3.0e-51	195	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
637678678	1005	32.75	156	495	1	330	2.0e-39	158	COG0642	Signal transduction histidine kinase	336
637678679	276	23.55	10	265	13	288	1.0e-25	110	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
637678680	355	34.91	246	350	16	121	1.0e-16	81.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
637678681	1116	31.62	45	180	10	143	2.0e-29	124	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
637678681	1116	37.12	187	445	1	259	4.0e-69	257	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
637678681	1116	38.33	550	1116	3	548	0.0e+00	531	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
637678682	1066	33.21	648	923	72	336	5.0e-38	153	COG0642	Signal transduction histidine kinase	336
637678684	442	25.88	15	437	4	453	5.0e-40	158	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
637678686	224	24.53	7	215	1	212	1.0e-20	93.8	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
637678687	655	35.75	14	618	16	611	0.0e+00	462	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
637678688	260	43.65	7	258	2	250	2.0e-81	295	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
637678689	304	33.11	1	299	3	293	5.0e-38	151	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
637678690	358	33.03	22	350	1	314	3.0e-40	159	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
637678691	440	20.33	39	400	21	357	2.0e-12	67.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637678692	291	50.62	29	269	4	237	1.0e-79	290	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
637678693	409	32.54	1	401	8	427	7.0e-61	228	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
637678695	392	39.03	11	388	6	396	5.0e-90	324	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
637678698	286	36.55	6	286	2	290	6.0e-39	154	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
637678699	146	32.65	1	146	1	140	1.0e-13	69.2	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
637678700	299	35.71	1	299	3	310	2.0e-28	120	COG0679	Predicted permease	311
637678702	221	39.25	2	215	1	208	8.0e-43	167	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
637678703	697	27.33	267	577	20	332	5.0e-35	143	COG0642	Signal transduction histidine kinase	336
637678705	1150	31.94	22	706	1	637	0.0e+00	606	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
637678706	462	40.09	21	461	10	458	3.0e-93	336	COG0277	FAD/FMN-containing dehydrogenase	459
637678708	460	35.65	33	383	1	356	3.0e-52	199	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637678709	319	43.56	12	314	2	293	3.0e-57	215	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
637678710	353	43.95	8	346	2	312	3.0e-50	192	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
637678711	253	54.94	2	253	1	250	3.0e-84	304	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
637678712	234	58.97	1	233	3	236	1.0e-88	319	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
637678713	277	38.68	32	274	1	217	4.0e-39	155	COG0850	Septum formation inhibitor MinC	219
637678714	271	64.21	1	271	1	270	3.0e-116	411	COG2894	Septum formation inhibitor-activating ATPase MinD	272
637678715	85	46.43	1	84	1	83	5.0e-20	89.1	COG0851	Septum formation topological specificity factor MinE	88
637678716	210	21.83	77	209	1	139	2.0e-13	69	COG3650	Uncharacterized membrane protein	149
637678717	336	33.33	9	92	12	98	8.0e-13	68.2	COG0633	Ferredoxin	102
637678717	336	33.78	100	324	5	219	3.0e-47	182	COG0543	NAD(P)H-flavin reductase	252
637678718	296	21.9	3	289	2	306	2.0e-17	83.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
637678719	138	44.76	1	138	8	149	4.0e-30	123	COG1981	Uncharacterized membrane protein	149
637678720	380	39.47	1	377	2	381	5.0e-97	348	COG0116	23S rRNA G2445 N2-methylase RlmL	381
637678721	431	32.15	1	431	6	471	6.0e-80	291	COG0427	Acyl-CoA hydrolase	501
637678725	314	60.39	8	314	1	306	0.0e+00	471	COG0320	Lipoate synthase	306
637678726	205	56.65	1	201	9	211	7.0e-73	266	COG0321	Lipoate-protein ligase B	221
637678727	89	42.68	8	89	9	90	1.0e-22	98	COG2921	Putative lipoic acid-binding regulatory protein	90
637678728	291	32.27	9	283	4	279	3.0e-48	185	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
637678729	391	44.01	12	391	5	386	3.0e-103	368	COG1686	D-alanyl-D-alanine carboxypeptidase	389
637678730	302	26.33	4	301	1	295	1.0e-22	100	COG0583	DNA-binding transcriptional regulator, LysR family	297
637678731	292	34.92	1	289	15	293	9.0e-41	160	COG0501	Zn-dependent protease with chaperone function	302
637678732	420	25.37	23	411	33	441	1.0e-23	104	COG1538	Outer membrane protein TolC	457
637678733	379	28.31	37	364	33	356	1.0e-17	84.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
637678734	1036	50.05	1	1029	1	1018	0.0e+00	1213	COG3696	Cu/Ag efflux pump CusA	1027
637678735	112	37.5	1	104	1	102	1.0e-18	84.8	COG0347	Nitrogen regulatory protein PII	112
637678736	306	18.63	33	190	15	174	5.0e-09	55.4	COG2203	GAF domain	175
637678739	263	44.73	1	261	5	277	2.0e-65	242	COG0682	Prolipoprotein diacylglyceryltransferase	287
637678740	618	53.48	1	614	8	575	0.0e+00	785	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
637678741	205	41.06	1	203	1	207	9.0e-28	116	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
637678742	101	45.83	7	101	11	106	7.0e-14	69	COG4654	Cytochrome c551/c552	110
637678746	396	83.84	1	396	1	394	0.0e+00	726	COG0050	Translation elongation factor EF-Tu, a GTPase	394
637678748	117	42.42	38	103	2	67	5.0e-07	46.5	COG0690	Preprotein translocase subunit SecE	73
637678749	177	56.82	1	176	1	176	5.0e-54	203	COG0250	Transcription antitermination factor NusG	178
637678750	143	69.5	2	142	1	140	1.0e-52	198	COG0080	Ribosomal protein L11	141
637678751	231	61.4	1	227	1	228	2.0e-77	282	COG0081	Ribosomal protein L1	228
637678752	165	46.58	1	159	1	161	3.0e-31	128	COG0244	Ribosomal protein L10	175
637678753	123	66.94	1	123	1	124	2.0e-25	108	COG0222	Ribosomal protein L7/L12	124
637678755	1403	49.83	20	855	7	808	0.0e+00	874	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
637678756	125	78.05	1	123	7	129	2.0e-49	187	COG0048	Ribosomal protein S12	129
637678757	156	62.84	2	149	1	148	7.0e-52	196	COG0049	Ribosomal protein S7	148
637678758	697	66	1	697	1	691	0.0e+00	1014	COG0480	Translation elongation factor EF-G, a GTPase	697
637678759	396	83.84	1	396	1	394	0.0e+00	726	COG0050	Translation elongation factor EF-Tu, a GTPase	394
637678760	103	72.82	1	103	1	103	4.0e-38	149	COG0051	Ribosomal protein S10	104
637678761	212	57.08	2	212	1	212	5.0e-71	260	COG0087	Ribosomal protein L3	218
637678762	207	41.9	1	207	2	211	2.0e-55	208	COG0088	Ribosomal protein L4	214
637678763	100	51.61	6	97	1	93	5.0e-20	89.5	COG0089	Ribosomal protein L23	94
637678764	275	60.73	1	274	1	275	1.0e-106	379	COG0090	Ribosomal protein L2	275
637678765	91	68.48	1	91	1	92	4.0e-35	139	COG0185	Ribosomal protein S19	93
637678766	109	60.19	1	108	9	116	3.0e-33	133	COG0091	Ribosomal protein L22	120
637678767	261	54.94	12	240	1	233	1.0e-78	286	COG0092	Ribosomal protein S3	233
637678768	137	61.03	1	134	2	137	1.0e-46	178	COG0197	Ribosomal protein L16/L10AE	146
637678769	64	56.67	2	61	4	63	4.0e-08	49.5	COG0255	Ribosomal protein L29	69
637678770	88	65.38	8	85	8	85	1.0e-20	91.4	COG0186	Ribosomal protein S17	87
637678771	122	73.77	1	122	1	122	1.0e-49	188	COG0093	Ribosomal protein L14	122
637678772	106	52.83	1	105	1	104	3.0e-19	86.9	COG0198	Ribosomal protein L24	104
637678773	179	65.92	1	179	1	179	8.0e-75	272	COG0094	Ribosomal protein L5	180
637678774	101	67.21	41	101	1	61	2.0e-17	81	COG0199	Ribosomal protein S14	61
637678775	131	59.54	1	130	1	131	6.0e-45	172	COG0096	Ribosomal protein S8	132
637678776	176	54.24	1	175	1	176	1.0e-55	209	COG0097	Ribosomal protein L6P/L9E	178
637678777	118	51.24	1	118	5	125	6.0e-28	116	COG0256	Ribosomal protein L18	125
637678778	175	51.14	1	175	5	180	1.0e-50	192	COG0098	Ribosomal protein S5	181
637678779	60	51.85	6	59	1	54	6.0e-13	65.9	COG1841	Ribosomal protein L30/L7E	55
637678780	144	50.68	1	142	1	148	1.0e-29	122	COG0200	Ribosomal protein L15	152
637678781	440	52.55	5	429	7	432	0.0e+00	466	COG0201	Preprotein translocase subunit SecY	436
637678782	72	65.28	1	72	1	72	3.0e-23	99.9	COG0361	Translation initiation factor IF-1	75
637678784	120	61.98	1	120	1	121	2.0e-41	160	COG0099	Ribosomal protein S13	121
637678785	129	68.99	1	129	1	129	5.0e-47	179	COG0100	Ribosomal protein S11	129
637678786	209	50.95	1	209	1	205	7.0e-52	197	COG0522	Ribosomal protein S4 or related protein	205
637678787	324	53.5	6	318	1	313	7.0e-95	340	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
637678788	132	70.69	1	116	1	116	2.0e-44	171	COG0203	Ribosomal protein L17	116
637678790	605	61.09	97	591	1	496	0.0e+00	661	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
637678791	151	45.8	20	150	2	131	1.0e-33	135	COG1607	Acyl-CoA hydrolase	157
637678792	401	34.62	1	401	1	440	6.0e-76	278	COG2067	Long-chain fatty acid transport protein	440
637678794	265	20.65	25	264	20	264	3.0e-06	46.2	COG3087	Cell division protein FtsN	264
637678797	127	51.56	1	126	2	129	2.0e-29	121	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
637678798	683	51.91	1	676	3	677	0.0e+00	824	COG1200	RecG-like helicase	677
637678799	286	29.29	1	285	1	295	2.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
637678800	400	17.74	21	391	24	394	4.0e-13	69.8	COG2814	Predicted arabinose efflux permease, MFS family	394
637678801	327	33.73	2	325	1	326	1.0e-51	197	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
637678802	67	50	1	64	1	64	4.0e-16	76.1	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
637678803	355	44.2	1	354	3	353	4.0e-103	368	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
637678805	295	24.83	5	295	1	280	3.0e-19	89.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
637678806	437	58.23	203	437	1	237	3.0e-86	312	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
637678807	253	52.78	1	251	2	250	6.0e-83	300	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
637678808	310	36.81	8	308	8	314	1.0e-44	173	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
637678809	291	40.2	1	290	2	297	2.0e-44	173	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
637678810	349	26.14	1	84	4	91	5.0e-08	52.4	COG0633	Ferredoxin	102
637678810	349	29.46	107	345	8	243	4.0e-36	145	COG1018	Ferredoxin-NADP reductase	266
637678812	554	20.78	93	525	42	437	1.0e-27	118	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
637678813	264	38.93	1	261	2	257	2.0e-50	192	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
637678814	519	47.74	22	308	6	292	1.0e-82	301	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
637678815	156	28.87	9	146	1	141	1.0e-16	78.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
637678816	441	56.41	14	439	15	437	0.0e+00	492	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
637678817	401	41.75	1	401	1	392	1.0e-85	310	COG0183	Acetyl-CoA acetyltransferase	392
637678818	381	30.52	18	378	2	358	3.0e-46	179	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637678819	337	45.32	37	302	1	265	2.0e-92	333	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
637678820	97	64.36	7	97	9	109	2.0e-31	127	COG3460	1,2-phenylacetyl-CoA epoxidase, PaaB subunit	117
637678821	260	41.76	3	260	19	265	2.0e-55	209	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
637678822	166	30.53	6	96	15	108	8.0e-17	79.9	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
637678823	365	28.04	5	300	4	265	4.0e-45	175	COG1018	Ferredoxin-NADP reductase	266
637678823	365	29.76	278	355	6	89	7.0e-09	55.4	COG0633	Ferredoxin	102
637678824	257	41.25	1	254	3	257	4.0e-57	214	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
637678825	259	36.92	1	258	3	257	8.0e-42	164	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
637678826	265	34.01	12	258	1	246	1.0e-42	166	COG1414	DNA-binding transcriptional regulator, IclR family	246
637678827	203	47.7	5	178	3	176	2.0e-51	195	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
637678828	352	31.85	55	345	5	284	9.0e-52	197	COG3327	DNA-binding transcriptional regulator PaaX (phenylacetic acid degradation)	291
637678831	1727	33.33	106	1697	89	1618	0.0e+00	920	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
637678832	780	44.94	15	779	2	731	0.0e+00	691	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
637678833	1094	29.66	5	648	6	526	1.0e-102	368	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
637678841	103	36.67	14	103	13	102	3.0e-08	50.2	COG0640	DNA-binding transcriptional regulator, ArsR family	110
637678842	713	31.03	199	712	3	527	3.0e-80	293	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
637678842	713	31.48	2	211	35	250	1.0e-20	95.8	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
637678847	252	22.44	18	252	31	284	3.0e-08	52.1	COG0682	Prolipoprotein diacylglyceryltransferase	287
637678849	474	28.94	14	472	15	505	4.0e-70	259	COG1964	Uncharacterized Fe-S cluster-containing enzyme, radical SAM superfamily	514
637678853	296	38.54	3	289	3	289	2.0e-49	189	COG0382	4-hydroxybenzoate polyprenyltransferase	289
637678855	487	57.91	1	487	1	475	0.0e+00	659	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
637678857	457	20.79	70	437	6	363	2.0e-44	173	COG0641	Sulfatase maturation enzyme AslB, radical SAM superfamily	378
637678860	787	30.56	353	639	60	336	1.0e-39	158	COG0642	Signal transduction histidine kinase	336
637678860	787	37.4	657	785	2	130	7.0e-23	103	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
637678863	479	31.71	2	468	6	467	2.0e-77	283	COG2027	D-alanyl-D-alanine carboxypeptidase	470
637678864	715	25.74	312	542	1	232	3.0e-11	64.2	COG2202	PAS domain	232
637678864	715	47.8	530	710	1	181	4.0e-45	176	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
637678865	96	65.96	1	94	1	94	1.0e-32	131	COG0234	Co-chaperonin GroES (HSP10)	96
637678866	550	48.45	1	533	1	523	0.0e+00	493	COG0459	Chaperonin GroEL (HSP60 family)	524
637678867	102	42.16	1	102	2	102	2.0e-19	87.2	COG3162	Uncharacterized membrane protein, DUF485 family	102
637678868	559	51.41	33	551	2	529	0.0e+00	500	COG4147	Na+(or H+)/acetate symporter ActP	529
637678869	223	44.78	1	221	1	229	5.0e-57	214	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
637678870	501	32.19	162	480	20	334	2.0e-47	183	COG0642	Signal transduction histidine kinase	336
637678874	160	31.39	10	137	2	138	2.0e-22	98.4	COG2062	Phosphohistidine phosphatase SixA	163
637678875	372	62.5	95	342	23	270	1.0e-102	366	COG2326	Polyphosphate kinase 2, PPK2 family	270
637678876	163	28.03	32	162	20	136	1.0e-11	62.7	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
637678878	296	39.44	31	276	6	251	7.0e-55	207	COG0631	Serine/threonine protein phosphatase PrpC	262
637678879	457	31.89	9	308	2	318	6.0e-46	178	COG0515	Serine/threonine protein kinase	384
637678881	591	47.41	115	575	2	454	0.0e+00	465	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
637678882	546	44.24	117	546	1	403	6.0e-94	338	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
637678883	891	64.02	13	889	8	885	0.0e+00	1356	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
637678886	199	26.7	24	199	34	207	4.0e-22	98	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
637678887	624	42.95	1	608	2	627	0.0e+00	532	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
637678888	203	32.34	6	203	5	200	1.0e-25	109	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
637678889	284	64.54	4	284	1	282	1.0e-112	399	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
637678890	166	68.15	5	161	1	155	1.0e-56	212	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
637678891	109	48.57	1	105	2	106	4.0e-18	83.2	COG2076	Multidrug transporter EmrE and related cation transporters	106
637678892	386	48.63	12	374	2	361	5.0e-122	431	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
637678893	331	45.67	2	208	10	210	5.0e-59	221	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
637678894	112	42.39	22	111	6	97	1.0e-20	91.9	COG2154	Pterin-4a-carbinolamine dehydratase	101
637678897	468	43.31	1	464	105	560	1.0e-122	433	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
637678898	465	21.4	4	459	6	438	3.0e-62	233	COG2610	H+/gluconate symporter or related permease	442
637678899	667	57.14	17	539	2	518	0.0e+00	687	COG4670	Acyl CoA:acetate/3-ketoacid CoA transferase	527
637678900	378	32.36	41	372	27	367	4.0e-17	82.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
637678901	1027	32.23	2	1007	1	1009	0.0e+00	755	COG0841	Multidrug efflux pump subunit AcrB	1009
637678902	835	39.39	705	834	4	130	2.0e-20	94.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
637678903	1218	21.08	7	1197	18	1274	4.0e-70	260	COG2911	Autotransporter translocation and assembly factor TamB	1278
637678904	559	28.26	1	559	11	594	3.0e-72	266	COG0729	Outer membrane translocation and assembly module TamA	594
637678905	686	31.41	8	679	9	665	5.0e-98	352	COG4389	Site-specific recombinase	677
637678906	217	31.79	44	216	27	190	1.0e-25	110	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
637678907	729	34.7	23	324	3	297	4.0e-43	170	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
637678910	1134	21.36	23	1093	18	1111	7.0e-78	286	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
637678911	250	22.18	1	247	4	265	1.0e-19	90.5	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
637678913	555	37.22	27	555	15	547	1.0e-124	440	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
637678914	124	56.41	7	123	2	118	2.0e-30	124	COG0818	Diacylglycerol kinase	123
637678915	941	68.48	1	939	3	935	0.0e+00	1579	COG0178	Excinuclease UvrABC ATPase subunit	935
637678916	261	23.79	2	261	17	301	1.0e-22	100	COG0501	Zn-dependent protease with chaperone function	302
637678918	319	34.72	1	286	1	283	8.0e-29	121	COG0583	DNA-binding transcriptional regulator, LysR family	297
637678919	443	48.7	1	443	1	459	0.0e+00	495	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
637678920	616	49.19	1	614	1	603	0.0e+00	579	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
637678921	251	24.31	1	251	4	256	1.0e-13	70.4	COG0730	Uncharacterized membrane protein YfcA	258
637678922	433	44.88	3	410	1	403	6.0e-90	324	COG1301	Na+/H+-dicarboxylate symporter	415
637678923	474	66.52	3	465	1	463	0.0e+00	726	COG1027	Aspartate ammonia-lyase	471
637678924	407	23.14	8	391	1	382	9.0e-17	81.8	COG2814	Predicted arabinose efflux permease, MFS family	394
637678925	156	44.31	2	156	1	167	8.0e-36	142	COG0629	Single-stranded DNA-binding protein	167
637678926	282	22.89	8	280	7	287	4.0e-21	95.4	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
637678927	630	58.25	1	630	1	627	0.0e+00	800	COG3158	K+ transporter	627
637678930	185	55.63	37	173	10	151	1.0e-51	196	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
637678931	266	42.24	9	261	5	280	7.0e-62	230	COG1469	GTP cyclohydrolase FolE2	289
637678932	439	45.31	3	426	7	425	9.0e-119	420	COG2907	Predicted NAD/FAD-binding protein	447
637678933	254	36.89	4	244	6	247	1.0e-46	180	COG3496	Uncharacterized conserved protein, DUF1365 family	261
637678934	394	45.64	114	393	2	283	7.0e-78	284	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
637678936	407	25.65	5	400	13	437	1.0e-35	144	COG2211	Na+/melibiose symporter or related transporter	467
637678938	251	29.69	9	248	5	259	9.0e-35	140	COG0300	Short-chain dehydrogenase	265
637678942	222	39.29	2	194	1	195	3.0e-31	128	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
637678943	196	53.41	6	181	4	176	6.0e-57	213	COG0279	Phosphoheptose isomerase	176
637678945	120	47.71	12	116	4	112	3.0e-26	110	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
637678946	279	52.19	5	277	4	275	1.0e-86	312	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
637678948	366	63.85	23	365	2	343	0.0e+00	527	COG0418	Dihydroorotase	344
637678951	87	63.38	1	71	1	71	1.0e-21	94.5	COG0361	Translation initiation factor IF-1	75
637678952	293	21.36	1	278	10	318	3.0e-22	99.4	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
637678953	568	32.78	31	451	3	396	3.0e-97	349	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
637678954	158	45.1	1	153	4	154	4.0e-32	130	COG1522	DNA-binding transcriptional regulator, Lrp family	154
637678958	391	59.8	1	391	1	392	0.0e+00	510	COG3825	Uncharacterized conserved protein,  contains von Willebrand factor type A (vWA) domain	393
637678959	301	24.56	16	286	12	278	4.0e-34	138	COG0714	MoxR-like ATPase	329
637678961	384	31.3	141	348	44	258	6.0e-18	85.4	COG2890	Methylase of polypeptide chain release factors	280
637678962	128	56.03	13	128	25	138	3.0e-32	130	COG4315	Predicted lipoprotein with conserved Yx(FWY)xxD motif (function unknown)	138
637678963	166	41.36	2	156	17	178	3.0e-25	108	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
637678964	264	34.34	1	261	1	256	2.0e-32	133	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
637678966	382	31.13	13	382	1	365	2.0e-47	183	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637678969	657	45	296	653	1	342	1.0e-91	331	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
637678970	578	36.32	1	578	1	567	6.0e-120	424	COG0358	DNA primase (bacterial type)	568
637678971	148	55.41	1	147	1	148	3.0e-32	131	COG1610	Uncharacterized conserved protein YqeY	148
637678972	70	61.9	1	63	1	63	5.0e-08	49.5	COG0828	Ribosomal protein S21	67
637678973	358	54.68	15	354	1	339	1.0e-122	433	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
637678975	166	63.69	3	159	2	158	3.0e-63	234	COG2077	Peroxiredoxin	158
637678976	198	49.49	1	193	3	200	9.0e-45	173	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
637678977	116	34.48	1	115	2	117	2.0e-20	91	COG1539	Dihydroneopterin aldolase	121
637678978	163	34.21	10	160	2	153	7.0e-31	126	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
637678980	302	58.02	12	302	9	300	3.0e-101	361	COG4974	Site-specific recombinase XerD	300
637678981	162	34.78	17	158	12	167	9.0e-31	126	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
637678982	391	36.48	14	391	1	392	3.0e-80	292	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
637678983	418	57.63	6	417	4	416	0.0e+00	570	COG0014	Gamma-glutamyl phosphate reductase	417
637678985	335	33.23	3	334	1	333	3.0e-53	202	COG1466	DNA polymerase III, delta subunit	334
637678986	172	27.11	1	164	1	162	6.0e-21	93.8	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
637678987	876	49.03	7	876	1	814	0.0e+00	1013	COG0495	Leucyl-tRNA synthetase	814
637678989	713	44.73	8	640	3	651	0.0e+00	592	COG0210	Superfamily I DNA or RNA helicase	655
637678990	252	30.29	11	250	1	221	6.0e-21	94.5	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
637678991	324	48.47	4	324	3	326	2.0e-78	286	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
637678992	441	28.57	21	326	5	321	1.0e-35	144	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
637678993	208	25	1	205	2	250	2.0e-20	92.6	COG1192	Cellulose biosynthesis protein BcsQ	259
637678994	1026	37.69	604	870	72	326	4.0e-42	167	COG0642	Signal transduction histidine kinase	336
637678995	303	32.09	3	294	1	291	2.0e-27	116	COG0583	DNA-binding transcriptional regulator, LysR family	297
637678996	235	41.06	1	234	1	245	3.0e-48	185	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
637678997	184	27.88	1	182	3	205	3.0e-20	91.7	COG0655	Multimeric flavodoxin WrbA	207
637679000	375	19.18	89	370	96	376	4.0e-12	66.2	COG4692	Predicted neuraminidase (sialidase)	381
637679001	262	38.37	4	259	2	257	3.0e-47	182	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
637679002	1156	45.96	3	1128	1	1119	0.0e+00	1247	COG0587	DNA polymerase III, alpha subunit	1139
637679004	505	26.75	7	335	85	408	2.0e-39	157	COG0840	Methyl-accepting chemotaxis protein	408
637679006	221	54.87	23	217	1	194	5.0e-75	274	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
637679007	481	42.92	1	481	5	488	2.0e-106	379	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
637679010	503	30.83	18	502	2	487	1.0e-55	210	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
637679011	485	43.04	1	477	1	480	1.0e-95	344	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
637679013	112	72.73	4	112	3	112	4.0e-43	166	COG2824	Uncharacterized Zn-ribbon-containing protein	112
637679014	563	41.5	1	552	1	551	1.0e-113	404	COG0659	Sulfate permease or related transporter, MFS superfamily	554
637679017	696	36.94	589	695	13	123	1.0e-22	101	COG0073	tRNA-binding EMAP/Myf domain	123
637679017	696	41.42	1	555	3	558	0.0e+00	626	COG0143	Methionyl-tRNA synthetase	558
637679018	227	42.54	1	223	1	227	4.0e-50	191	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
637679019	363	41.82	43	314	4	265	3.0e-60	226	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
637679020	188	42.19	2	188	1	181	4.0e-60	223	COG0717	Deoxycytidine triphosphate deaminase	183
637679021	742	42.23	138	742	1	556	0.0e+00	602	COG1982	Arginine/lysine/ornithine decarboxylase	557
637679022	163	45.78	4	163	2	167	1.0e-40	159	COG0262	Dihydrofolate reductase	167
637679023	485	48.44	6	478	3	476	0.0e+00	487	COG0297	Glycogen synthase	487
637679024	526	48.95	44	518	3	446	0.0e+00	504	COG0166	Glucose-6-phosphate isomerase	446
637679025	856	29.62	20	796	5	749	0.0e+00	558	COG0058	Glucan phosphorylase	750
637679026	657	16.52	2	455	1	432	3.0e-20	93.9	COG1449	Alpha-amylase/alpha-mannosidase, GH57 family	615
637679027	551	26.47	3	533	5	499	5.0e-56	212	COG1449	Alpha-amylase/alpha-mannosidase, GH57 family	615
637679028	440	54.55	27	432	2	386	0.0e+00	527	COG0448	ADP-glucose pyrophosphorylase	393
637679029	621	53.97	1	620	5	628	0.0e+00	714	COG0296	1,4-alpha-glucan branching enzyme	628
637679033	245	33.63	24	244	7	226	3.0e-36	145	COG4291	Uncharacterized membrane protein	228
637679035	309	37.14	3	309	9	320	5.0e-66	244	COG0837	Glucokinase	320
637679036	264	73.68	1	264	3	268	1.0e-124	439	COG0207	Thymidylate synthase	268
637679038	196	46.33	4	179	7	169	3.0e-45	175	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
637679039	179	46.39	1	165	15	180	2.0e-37	148	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
637679040	447	38.82	15	447	2	454	4.0e-95	341	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
637679041	362	62.78	1	357	1	360	0.0e+00	493	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
637679042	175	52.6	21	174	3	156	2.0e-49	188	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
637679043	487	71.06	10	439	9	440	0.0e+00	556	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
637679044	197	55.81	1	172	1	172	4.0e-51	194	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
637679045	218	38.35	8	211	1	205	5.0e-37	147	COG0406	Broad specificity phosphatase PhoE	208
637679046	416	65.78	3	415	2	413	0.0e+00	643	COG0112	Glycine/serine hydroxymethyltransferase	413
637679047	154	57.14	1	154	1	154	5.0e-47	180	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
637679048	367	43.38	148	361	1	216	4.0e-52	199	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
637679048	367	71.72	3	147	2	146	3.0e-61	229	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
637679049	253	49.01	1	248	3	254	5.0e-70	257	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
637679051	480	44.33	10	387	1	369	7.0e-95	341	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
637679052	477	31.73	19	473	2	417	4.0e-57	215	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
637679053	98	36.96	4	94	8	99	1.0e-08	51.3	COG0640	DNA-binding transcriptional regulator, ArsR family	110
637679054	141	47.57	36	137	7	109	2.0e-23	101	COG0607	Rhodanese-related sulfurtransferase	110
637679055	86	55.7	3	80	1	79	1.0e-19	88.1	COG0695	Glutaredoxin	80
637679056	152	56.64	3	145	7	149	4.0e-45	173	COG1952	Preprotein translocase subunit SecB	157
637679058	329	48.33	1	327	2	329	3.0e-107	382	COG0240	Glycerol-3-phosphate dehydrogenase	329
637679059	154	58.82	1	152	2	153	2.0e-59	221	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
637679060	247	40.99	29	246	8	225	2.0e-43	169	COG1040	Predicted amidophosphoribosyltransferases	225
637679061	327	55.19	20	325	13	318	1.0e-116	413	COG0502	Biotin synthase or related enzyme	335
637679062	297	26.29	12	183	9	176	2.0e-14	73.4	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
637679063	221	41.24	7	200	5	196	3.0e-36	145	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
637679064	317	38.43	20	288	1	266	5.0e-55	208	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
637679065	279	27.71	40	279	39	279	1.0e-20	94.3	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
637679066	143	36.84	12	123	6	117	3.0e-15	74	COG0517	CBS domain	117
637679067	211	44.8	7	131	2	120	5.0e-21	94.7	COG2863	Cytochrome c553	121
637679068	220	43.43	1	198	1	197	1.0e-59	223	COG0218	GTP-binding protein EngB required for normal cell division	200
637679069	334	60.86	8	334	5	329	0.0e+00	512	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
637679070	202	22.91	1	179	6	181	3.0e-07	48.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
637679071	212	25.73	1	193	2	206	1.0e-20	93	COG1011	FMN phosphatase YigB, HAD superfamily	229
637679072	295	55.76	26	292	1	263	4.0e-86	311	COG0548	Acetylglutamate kinase	265
637679073	138	35.51	1	138	13	144	8.0e-21	92.8	COG0071	Molecular chaperone IbpA, HSP20 family	146
637679074	150	19.46	1	147	5	152	2.0e-08	51.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
637679077	599	64.86	1	589	1	585	0.0e+00	942	COG0173	Aspartyl-tRNA synthetase	585
637679078	209	48.28	6	207	6	208	1.0e-59	222	COG2928	Uncharacterized membrane protein	222
637679079	83	40.91	1	66	8	72	5.0e-14	69.3	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
637679080	284	46.95	12	272	6	242	4.0e-37	148	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
637679081	408	41.77	16	408	3	396	3.0e-108	385	COG1459	Type II secretory pathway, component PulF	397
637679082	571	47.42	70	570	5	499	0.0e+00	550	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
637679083	423	41.23	5	423	1	419	9.0e-115	407	COG4536	Mg2+ and Co2+ transporter CorB, contains DUF21, CBS pair, and CorC-HlyC domains	423
637679084	279	40.6	45	278	34	265	7.0e-46	177	COG4137	ABC-type uncharacterized transport system, permease component	265
637679085	455	58.28	1	452	1	450	0.0e+00	585	COG0541	Signal recognition particle GTPase	451
637679086	203	23.7	1	203	61	271	2.0e-11	62.5	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
637679087	576	45.61	1	566	1	495	0.0e+00	572	COG0442	Prolyl-tRNA synthetase	500
637679088	182	20.13	13	162	17	161	5.0e-07	47.7	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
637679090	207	45.59	4	207	2	204	6.0e-55	207	COG2941	Demethoxyubiquinone hydroxylase, CLK1/Coq7/Cat5 family	204
637679091	142	42.03	1	138	2	135	1.0e-31	128	COG1765	Uncharacterized OsmC-related protein	137
637679092	142	62.24	1	142	1	143	9.0e-53	198	COG0102	Ribosomal protein L13	148
637679093	130	62.31	1	130	1	130	1.0e-44	171	COG0103	Ribosomal protein S9	130
637679095	133	31.93	1	119	9	122	1.0e-19	89.2	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
637679096	116	57.8	7	115	1	109	4.0e-41	159	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
637679102	318	23.83	31	262	31	241	1.0e-13	70.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
637679103	255	53.17	5	252	9	255	4.0e-83	301	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
637679105	341	38.96	23	341	1	322	2.0e-79	289	COG0142	Geranylgeranyl pyrophosphate synthase	322
637679109	537	28.96	268	518	72	325	4.0e-28	119	COG0642	Signal transduction histidine kinase	336
637679110	451	47.25	13	451	3	457	0.0e+00	481	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
637679112	386	39.8	6	386	1	391	2.0e-95	343	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
637679113	614	64.03	5	597	9	594	0.0e+00	891	COG1274	Phosphoenolpyruvate carboxykinase, GTP-dependent	608
637679114	759	45.71	434	758	5	323	1.0e-97	351	COG0280	Phosphotransacetylase	327
637679114	759	55.79	5	433	16	432	0.0e+00	557	COG0281	Malic enzyme	432
637679116	242	38.59	2	237	7	246	4.0e-52	198	COG1414	DNA-binding transcriptional regulator, IclR family	246
637679118	480	43.95	6	474	1	459	0.0e+00	505	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
637679120	318	40.19	15	315	15	318	8.0e-73	267	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
637679122	544	31.46	189	544	57	408	2.0e-49	190	COG0840	Methyl-accepting chemotaxis protein	408
637679124	71	47.89	1	71	1	71	9.0e-14	68.7	COG2501	Ribosome-associated protein YbcJ, S4-like RNA binding protein	73
637679126	214	20.47	8	212	2	216	3.0e-11	62.2	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
637679127	349	36.15	6	345	1	326	2.0e-51	196	COG0306	Phosphate/sulfate permease	326
637679128	346	32.06	7	345	3	324	4.0e-35	142	COG1275	Tellurite resistance protein TehA and related permeases	329
637679129	471	37.83	27	403	1	353	8.0e-74	271	COG0348	Polyferredoxin	386
637679130	454	38.33	23	450	118	556	2.0e-94	339	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
637679131	427	24.24	1	409	4	411	3.0e-34	139	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
637679134	203	47.15	6	198	4	196	4.0e-56	210	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
637679135	136	35	27	105	15	94	3.0e-07	47.5	COG0640	DNA-binding transcriptional regulator, ArsR family	110
637679136	389	50	7	383	3	385	1.0e-99	357	COG3004	Na+/H+ antiporter NhaA	390
637679138	429	27.27	13	288	40	310	1.0e-18	88.3	COG3344	Retron-type reverse transcriptase	328
637679140	104	49.52	1	104	6	106	5.0e-19	85.9	COG4654	Cytochrome c551/c552	110
637679141	184	25.27	8	183	9	190	3.0e-16	78.3	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
637679142	171	28	27	151	1	125	1.0e-10	59.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
637679143	165	27.84	1	161	11	186	3.0e-27	114	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
637679145	439	30.42	16	424	15	428	6.0e-40	158	COG0038	H+/Cl- antiporter ClcA	443
637679146	111	39.78	1	93	10	99	8.0e-08	49	COG0640	DNA-binding transcriptional regulator, ArsR family	110
637679147	164	33.33	2	140	1	136	2.0e-25	108	COG0394	Protein-tyrosine-phosphatase	139
637679148	355	41.33	9	352	1	336	1.0e-75	277	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
637679152	226	42.92	2	223	1	225	5.0e-56	210	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
637679153	381	30.09	65	379	21	331	3.0e-39	156	COG0642	Signal transduction histidine kinase	336
637679154	636	25.99	24	446	18	447	1.0e-43	171	COG1538	Outer membrane protein TolC	457
637679155	209	38.73	1	204	23	174	7.0e-34	137	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
637679156	516	53.97	1	514	7	518	2.0e-117	416	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
637679159	255	34.98	1	251	1	251	2.0e-33	136	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
637679160	812	41.57	93	808	2	709	0.0e+00	659	COG2217	Cation transport ATPase	713
637679161	63	50.85	1	59	1	57	1.0e-13	68.4	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
637679162	475	72.4	5	471	8	478	0.0e+00	677	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
637679163	211	55.22	3	211	2	223	4.0e-82	297	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
637679164	58	25.45	1	55	5	59	7.0e-08	49.1	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
637679165	299	25	86	224	5	149	5.0e-11	62.3	COG2010	Cytochrome c, mono- and diheme variants	150
637679166	472	38.5	31	415	2	361	7.0e-76	278	COG0348	Polyferredoxin	386
637679167	173	38.51	12	157	3	149	4.0e-32	130	COG3198	Uncharacterized protein	172
637679170	157	31.03	9	147	1	145	3.0e-19	88.2	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
637679171	285	37.19	1	284	3	266	6.0e-56	211	COG1291	Flagellar motor component MotA	266
637679172	316	32.72	11	279	1	244	3.0e-45	175	COG1360	Flagellar motor protein MotB	244
637679173	405	22.19	16	345	68	402	2.0e-18	87	COG0840	Methyl-accepting chemotaxis protein	408
637679175	784	38.95	1	780	2	713	0.0e+00	619	COG0643	Chemotaxis protein histidine kinase CheA	716
637679176	166	43.15	20	165	19	164	2.0e-35	141	COG0835	Chemotaxis signal transduction protein	165
637679177	792	37.33	387	736	34	408	2.0e-52	201	COG0840	Methyl-accepting chemotaxis protein	408
637679178	945	38.57	560	897	46	408	4.0e-59	223	COG0840	Methyl-accepting chemotaxis protein	408
637679179	300	44.19	37	294	2	263	1.0e-73	270	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
637679180	201	42.24	15	173	1	161	4.0e-48	184	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
637679181	350	51.15	4	350	1	345	3.0e-101	362	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
637679182	101	28.09	13	101	16	104	5.0e-12	62.7	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
637679183	322	43.12	5	162	3	154	2.0e-29	123	COG0835	Chemotaxis signal transduction protein	165
637679184	311	38.99	10	166	3	159	3.0e-27	116	COG0835	Chemotaxis signal transduction protein	165
637679186	287	47.32	85	287	15	217	5.0e-53	201	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
637679187	639	39.03	70	620	169	706	2.0e-122	433	COG0643	Chemotaxis protein histidine kinase CheA	716
637679188	379	45.18	3	364	1	363	4.0e-109	388	COG1377	Flagellar biosynthesis protein FlhB	363
637679189	694	57.16	1	693	2	696	0.0e+00	855	COG1298	Flagellar biosynthesis pathway, component FlhA	696
637679190	487	27.16	1	462	1	402	1.0e-70	260	COG1419	Flagellar biosynthesis GTPase FlhF	407
637679191	296	28.3	23	283	3	259	8.0e-26	111	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
637679192	248	41.7	1	233	16	244	2.0e-54	205	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
637679193	246	41.3	1	246	1	247	1.0e-62	232	COG1291	Flagellar motor component MotA	266
637679194	257	37.3	1	242	1	240	2.0e-50	192	COG1360	Flagellar motor protein MotB	244
637679195	154	24.49	1	145	2	137	1.0e-06	45.8	COG3418	Flagellar biosynthesis/type III secretory pathway chaperone	146
637679197	225	29.52	1	225	1	220	7.0e-27	113	COG1261	Flagella basal body P-ring formation protein FlgA	220
637679198	135	41.67	1	130	1	130	5.0e-25	106	COG1815	Flagellar basal body rod protein FlgB	133
637679199	137	59.12	1	136	1	137	3.0e-43	167	COG1558	Flagellar basal body rod protein FlgC	137
637679200	229	41.23	1	228	1	221	3.0e-33	135	COG1843	Flagellar hook assembly protein FlgD	222
637679201	442	40.45	1	442	3	422	9.0e-77	281	COG1749	Flagellar hook protein FlgE	423
637679202	247	50.4	1	246	1	251	3.0e-73	268	COG4787	Flagellar basal body rod protein FlgF	251
637679203	260	57.95	1	260	1	263	1.0e-82	299	COG4786	Flagellar basal body rod protein FlgG	265
637679204	219	39.04	2	216	3	230	5.0e-46	177	COG2063	Flagellar basal body L-ring protein FlgH	230
637679205	364	52.45	9	364	4	365	4.0e-107	381	COG1706	Flagellar basal body P-ring protein FlgI	365
637679206	324	40.24	151	314	18	180	2.0e-39	156	COG1705	Flagellum-specific peptidoglycan hydrolase FlgJ	201
637679207	683	33.72	1	426	3	409	8.0e-65	242	COG1256	Flagellar hook-associated protein FlgK	552
637679208	326	21.97	3	324	1	355	7.0e-25	108	COG1344	Flagellin and related hook-associated protein FlgL	360
637679210	260	40.55	2	255	1	253	3.0e-39	155	COG1684	Flagellar biosynthesis protein FliR	258
637679211	83	55.42	1	83	7	89	4.0e-16	76.3	COG1987	Flagellar biosynthesis protein FliQ	89
637679212	248	56.68	1	246	1	247	2.0e-74	272	COG1338	Flagellar biosynthetic protein FliP	248
637679213	136	31.13	31	132	25	130	7.0e-15	73	COG3190	Flagellar biogenesis protein FliO	137
637679214	147	41.09	8	135	8	136	1.0e-22	98.9	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
637679215	338	44.92	3	325	2	324	9.0e-94	337	COG1868	Flagellar motor switch protein FliM	332
637679216	187	29.35	4	187	1	159	3.0e-21	94.9	COG1580	Flagellar basal body-associated protein FliL	159
637679218	151	33.79	1	145	1	145	1.0e-11	63	COG2882	Flagellar biosynthesis chaperone FliJ	148
637679219	472	56.43	15	472	3	439	0.0e+00	594	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
637679220	231	24.67	1	224	2	227	5.0e-21	95	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
637679221	334	49.1	1	331	6	337	3.0e-85	308	COG1536	Flagellar motor switch protein FliG	339
637679222	584	38.25	19	579	10	542	2.0e-116	413	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
637679223	397	33.97	136	390	76	332	4.0e-34	139	COG0642	Signal transduction histidine kinase	336
637679224	457	48.04	7	453	6	458	0.0e+00	477	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
637679225	107	49.38	27	107	26	105	2.0e-13	67.7	COG1677	Flagellar hook-basal body complex protein FliE	105
637679226	264	21.63	57	260	33	233	7.0e-10	58	COG5581	c-di-GMP-binding flagellar brake protein YcgR, contains PilZNR and PilZ domains	233
637679227	93	49.4	8	89	6	88	2.0e-20	90.7	COG2257	Type III secretion system substrate exporter, FlhB-like	92
637679230	135	46.34	7	129	5	122	5.0e-26	110	COG1516	Flagellin-specific chaperone FliS	132
637679231	452	31.9	1	448	3	483	1.0e-34	140	COG1345	Flagellar capping protein FliD	483
637679232	122	36.08	28	122	24	120	1.0e-15	75.3	COG1334	Uncharacterized conserved protein, FlaG/YvyC family	120
637679233	273	30.92	4	264	2	263	9.0e-24	103	COG1344	Flagellin and related hook-associated protein FlgL	360
637679234	796	25.38	59	254	51	246	4.0e-10	60.8	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
637679234	796	29.06	231	787	15	616	3.0e-77	283	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
637679236	585	40.91	409	582	4	178	2.0e-37	151	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
637679239	172	36.15	13	139	1	124	9.0e-26	109	COG3617	Prophage antirepressor	176
637679254	266	32.93	13	261	1	246	8.0e-41	160	COG1414	DNA-binding transcriptional regulator, IclR family	246
637679255	206	26.85	1	206	2	257	6.0e-19	87.6	COG1192	Cellulose biosynthesis protein BcsQ	259
637679262	537	39.85	1	508	1	514	1.0e-121	430	COG2812	DNA polymerase III, gamma/tau subunits	515
637679263	107	51.89	1	104	2	105	2.0e-23	101	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
637679264	199	56.92	1	195	2	196	2.0e-75	275	COG0353	Recombinational DNA repair protein RecR	198
637679265	198	36.55	1	197	2	171	6.0e-31	127	COG0723	Rieske Fe-S protein	177
637679266	433	47.98	20	414	8	372	1.0e-88	320	COG1290	Cytochrome b subunit of the bc complex	381
637679267	239	35.83	1	239	5	250	2.0e-49	189	COG2857	Cytochrome c1	250
637679268	198	34.17	2	185	1	198	1.0e-29	123	COG0625	Glutathione S-transferase	211
637679269	143	44.87	1	143	3	155	7.0e-38	149	COG2969	Stringent starvation protein B	155
637679270	907	34.98	3	703	39	763	0.0e+00	509	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
637679271	329	28.17	1	317	2	316	4.0e-50	192	COG0547	Anthranilate phosphoribosyltransferase	338
637679272	814	59.46	1	809	1	791	0.0e+00	1098	COG1251	NAD(P)H-nitrite reductase, large subunit	793
637679273	103	38.1	1	103	2	105	5.0e-24	102	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
637679275	270	31.34	1	262	3	259	1.0e-34	140	COG2116	Formate/nitrite transporter FocA, FNT family	265
637679276	574	25	269	558	1	305	2.0e-28	121	COG0515	Serine/threonine protein kinase	384
637679276	574	25.68	1	241	4	255	9.0e-26	112	COG0631	Serine/threonine protein phosphatase PrpC	262
637679281	404	38.65	5	392	6	406	3.0e-83	302	COG2223	Nitrate/nitrite transporter NarK	417
637679282	562	32.68	7	241	8	260	2.0e-45	177	COG0631	Serine/threonine protein phosphatase PrpC	262
637679283	406	24.36	4	390	1	382	2.0e-15	77.2	COG2814	Predicted arabinose efflux permease, MFS family	394
637679285	191	42.11	1	190	5	194	4.0e-39	154	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
637679286	425	26.9	30	367	6	335	1.0e-47	184	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
637679287	312	34.13	62	309	10	252	9.0e-46	177	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
637679288	266	49.61	4	261	3	248	1.0e-86	313	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
637679289	646	29.8	4	643	1	571	4.0e-101	362	COG3850	Signal transduction histidine kinase, nitrate/nitrite-specific	574
637679290	221	44.08	5	215	1	208	4.0e-55	207	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
637679292	258	30.29	10	204	21	227	2.0e-30	125	COG0421	Spermidine synthase	282
637679294	680	31.61	312	678	46	406	4.0e-50	193	COG0840	Methyl-accepting chemotaxis protein	408
637679295	646	44.75	1	536	1	528	0.0e+00	514	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
637679296	402	22.98	13	388	11	382	9.0e-12	64.9	COG2807	Cyanate permease	395
637679298	213	33.33	1	212	12	230	5.0e-31	127	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
637679300	205	41.55	9	199	68	274	5.0e-46	177	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
637679301	332	69.4	12	328	1	317	0.0e+00	515	COG0825	Acetyl-CoA carboxylase alpha subunit	317
637679302	323	34.3	7	274	1	276	2.0e-44	172	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
637679303	292	54.27	1	291	4	296	7.0e-90	323	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
637679304	374	31.66	1	373	1	341	7.0e-53	201	COG3317	Uncharacterized lipoprotein	342
637679305	255	33.33	1	252	3	264	5.0e-29	121	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
637679308	432	37.5	4	425	7	432	4.0e-98	351	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
637679309	230	36.41	17	229	18	233	2.0e-25	109	COG0670	Integral membrane protein, interacts with FtsH	233
637679311	382	21.18	3	323	4	276	2.0e-25	110	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
637679312	152	31.25	1	144	1	122	1.0e-22	99.2	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
637679313	278	24.91	19	274	13	248	6.0e-14	71.5	COG0731	Wyosine [tRNA(Phe)-imidazoG37] synthetase, radical SAM superfamily	296
637679315	149	33.64	14	120	9	116	3.0e-10	57.8	COG0517	CBS domain	117
637679316	366	56.71	2	359	1	364	0.0e+00	510	COG0082	Chorismate synthase	369
637679317	88	36.23	12	80	2	70	1.0e-09	54.9	COG2841	Uncharacterized conserved protein YdcH, DUF465 family	72
637679318	395	22.06	32	373	41	383	4.0e-07	49.8	COG2814	Predicted arabinose efflux permease, MFS family	394
637679319	468	56.26	1	468	1	423	0.0e+00	613	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
637679321	212	52.61	1	211	1	190	4.0e-74	270	COG0066	3-isopropylmalate dehydratase small subunit	191
637679322	350	53.35	1	350	4	345	5.0e-124	437	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
637679323	377	32.8	1	375	1	334	8.0e-92	330	COG0136	Aspartate-semialdehyde dehydrogenase	334
637679324	1036	28.22	3	766	8	696	7.0e-64	239	COG3170	Tfp pilus assembly protein FimV	755
637679326	262	48.44	1	256	2	257	9.0e-90	323	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
637679327	208	46.41	2	204	1	208	2.0e-56	212	COG0135	Phosphoribosylanthranilate isomerase	208
637679328	399	70.3	5	398	1	393	0.0e+00	690	COG0133	Tryptophan synthase beta chain	396
637679329	268	50.19	1	265	1	265	3.0e-82	298	COG0159	Tryptophan synthase alpha chain	265
637679330	289	59.23	1	287	1	286	2.0e-116	412	COG0777	Acetyl-CoA carboxylase beta subunit	294
637679331	436	44.29	1	436	4	425	1.0e-118	420	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
637679332	239	26.58	17	235	8	222	5.0e-12	64.7	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
637679333	163	27.33	1	160	1	161	4.0e-17	81.1	COG1286	Uncharacterized membrane protein, required for colicin V production	182
637679334	505	56.09	4	476	16	468	0.0e+00	594	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
637679335	393	48.98	6	393	5	395	2.0e-129	456	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
637679336	425	44.99	1	423	29	451	7.0e-117	414	COG0513	Superfamily II DNA and RNA helicase	513
637679337	569	45.96	63	566	2	500	0.0e+00	509	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
637679338	406	37.81	1	402	1	395	4.0e-92	331	COG1459	Type II secretory pathway, component PulF	397
637679342	176	21.48	22	151	2	136	8.0e-08	50.4	COG4970	Tfp pilus assembly protein FimT	181
637679352	275	38.64	1	262	9	269	8.0e-44	170	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
637679354	552	32.11	11	545	5	523	8.0e-101	361	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
637679355	278	27.38	13	263	1	246	1.0e-31	130	COG1414	DNA-binding transcriptional regulator, IclR family	246
637679356	216	26.64	1	212	14	223	1.0e-24	106	COG1802	DNA-binding transcriptional regulator, GntR family	230
637679357	586	23.4	8	373	2	344	2.0e-31	130	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
637679358	379	29.25	15	362	1	346	9.0e-38	151	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637679360	402	17.9	1	386	1	392	4.0e-21	96	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
637679361	183	35.29	32	181	13	162	3.0e-25	108	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
637679362	377	30.52	13	367	1	353	2.0e-40	160	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637679363	263	46.27	10	263	8	262	1.0e-66	246	COG3971	2-keto-4-pentenoate hydratase	264
637679364	304	57.65	1	293	1	304	4.0e-98	351	COG4569	Acetaldehyde dehydrogenase (acetylating)	310
637679365	343	21.43	6	330	1	334	2.0e-42	166	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
637679366	951	35.6	356	677	3	313	2.0e-45	178	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
637679366	951	51.6	702	950	2	250	1.0e-80	295	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
637679367	248	54.58	2	238	1	237	4.0e-81	294	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
637679368	194	22.22	1	177	7	182	4.0e-10	58.4	COG3945	Hemerythrin-like domain	189
637679369	289	29.24	25	289	9	281	9.0e-31	127	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
637679370	205	43.37	10	201	12	205	2.0e-47	182	COG3647	Uncharacterized membrane protein YjdF	205
637679371	617	49.5	15	615	1	586	0.0e+00	709	COG0514	Superfamily II DNA helicase RecQ	590
637679372	242	42.27	3	219	1	216	8.0e-45	173	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
637679373	163	52.12	1	163	1	157	2.0e-52	198	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
637679374	190	48.8	23	187	1	157	2.0e-48	185	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
637679375	431	24.37	158	428	44	297	3.0e-21	96.6	COG3034	Murein L,D-transpeptidase YafK	298
637679377	456	57.02	1	455	1	463	0.0e+00	663	COG0215	Cysteinyl-tRNA synthetase	464
637679378	382	23.74	25	379	5	357	3.0e-48	186	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637679379	382	23.97	22	379	1	357	5.0e-41	162	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637679380	378	62.17	1	376	1	369	0.0e+00	503	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
637679381	645	59.64	1	606	4	579	0.0e+00	655	COG0443	Molecular chaperone DnaK (HSP70)	579
637679382	184	44.71	19	184	24	193	2.0e-34	138	COG0576	Molecular chaperone GrpE (heat shock protein)	193
637679383	454	27.08	6	321	1	330	3.0e-38	153	COG0515	Serine/threonine protein kinase	384
637679384	539	32.62	166	539	40	408	2.0e-46	180	COG0840	Methyl-accepting chemotaxis protein	408
637679387	367	45.43	14	341	2	320	2.0e-100	359	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
637679388	342	40.88	1	337	3	341	1.0e-84	306	COG1420	Transcriptional regulator of heat shock response	346
637679389	309	41.72	18	304	1	281	2.0e-67	249	COG0061	NAD kinase	281
637679390	557	46.42	1	553	1	557	0.0e+00	520	COG0497	DNA repair ATPase RecN	557
637679391	201	38.59	13	195	1	183	8.0e-27	113	COG2119	Putative Ca2+/H+ antiporter, TMEM165/GDT1 family	190
637679392	147	45.32	5	143	10	145	6.0e-33	133	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
637679393	160	35.96	1	109	2	115	3.0e-22	98.2	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
637679394	268	55.3	5	267	4	266	1.0e-90	326	COG0289	Dihydrodipicolinate reductase	266
637679395	852	37.18	145	420	62	326	7.0e-44	173	COG0642	Signal transduction histidine kinase	336
637679396	385	62.8	7	376	1	364	0.0e+00	589	COG0505	Carbamoylphosphate synthase small subunit	368
637679397	1068	70	13	412	1	397	0.0e+00	582	COG0458	Carbamoylphosphate synthase large subunit	400
637679398	172	52.94	20	172	1	151	5.0e-41	160	COG0782	Transcription elongation factor, GreA/GreB family	151
637679400	120	43.68	4	90	2	88	1.0e-20	92.2	COG1534	RNA-binding protein YhbY	97
637679401	205	53.77	4	202	1	199	2.0e-70	258	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
637679402	626	61	9	600	1	596	0.0e+00	769	COG0465	ATP-dependent Zn proteases	596
637679403	279	44.74	14	275	6	267	4.0e-67	248	COG0294	Dihydropteroate synthase	274
637679404	450	45.67	1	447	5	459	2.0e-113	403	COG1109	Phosphomannomutase	464
637679405	249	53.78	1	249	1	248	6.0e-79	287	COG0149	Triosephosphate isomerase	251
637679406	123	54.43	4	82	1	78	2.0e-15	74.1	COG1314	Preprotein translocase subunit SecG	86
637679408	124	52.42	1	124	4	121	1.0e-29	121	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
637679409	158	68.59	3	158	13	168	5.0e-75	272	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
637679410	201	42.78	1	180	2	171	4.0e-41	161	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
637679411	417	58.51	1	417	9	398	0.0e+00	602	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
637679412	157	46.45	1	155	4	155	1.0e-47	182	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
637679413	442	58.73	1	423	3	424	0.0e+00	644	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
637679414	777	37.33	1	736	1	693	0.0e+00	591	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
637679415	349	49.26	11	346	4	332	1.0e-97	349	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
637679416	162	46.34	4	162	3	161	4.0e-44	170	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
637679417	198	42.17	1	166	1	164	1.0e-27	116	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
637679418	103	57	4	103	2	100	3.0e-19	86.7	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
637679419	682	42.46	5	677	1	606	0.0e+00	498	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
637679420	494	52.23	2	494	1	492	0.0e+00	524	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
637679421	494	44.21	8	490	3	471	7.0e-95	341	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
637679422	180	24.67	44	179	9	156	8.0e-06	43.8	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
637679423	964	33.56	49	604	133	689	1.0e-123	438	COG0209	Ribonucleotide reductase alpha subunit	696
637679424	681	30.07	4	143	3	143	4.0e-20	93.9	COG2703	Hemerythrin	144
637679425	746	48.53	233	741	1	500	0.0e+00	509	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
637679427	214	23.28	1	182	1	174	3.0e-09	55.3	COG2229	Signal recognition particle receptor subunit beta, a GTPase	187
637679429	438	35.9	1	372	8	353	9.0e-66	244	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
637679430	1187	30.71	365	604	1	232	2.0e-11	65.8	COG2202	PAS domain	232
637679432	1064	35.45	551	817	71	327	5.0e-40	160	COG0642	Signal transduction histidine kinase	336
637679433	393	45.34	5	391	3	393	6.0e-122	430	COG0282	Acetate kinase	396
637679434	472	30.26	192	463	23	323	2.0e-58	220	COG0280	Phosphotransacetylase	327
637679434	472	30.28	12	146	14	155	2.0e-16	80.9	COG2030	Acyl dehydratase	159
637679437	261	49.8	11	261	4	254	7.0e-83	300	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
637679438	632	28.03	5	161	3	159	1.0e-25	111	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
637679438	632	44.65	225	596	45	423	1.0e-118	421	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
637679441	487	42.83	16	475	4	437	1.0e-113	403	COG3259	Coenzyme F420-reducing hydrogenase, alpha subunit	441
637679442	166	23.77	3	118	2	118	2.0e-06	45.7	COG0680	Ni,Fe-hydrogenase maturation factor	160
637679443	381	44.97	13	365	8	360	7.0e-101	361	COG1932	Phosphoserine aminotransferase	365
637679445	328	28.24	10	252	17	275	2.0e-22	100	COG1566	Multidrug resistance efflux pump	352
637679446	920	44.09	270	546	4	282	3.0e-72	267	COG1131	ABC-type multidrug transport system, ATPase component	293
637679447	374	27.27	84	368	15	282	7.0e-19	88.4	COG0842	ABC-type multidrug transport system, permease component	286
637679450	147	36.91	1	147	4	151	3.0e-21	94.3	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
637679451	470	35.55	1	466	1	423	2.0e-85	310	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
637679452	582	42.48	130	581	7	445	5.0e-126	445	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
637679458	126	37.98	1	125	1	129	5.0e-19	86.9	COG3094	Uncharacterized membrane protein SirB2	129
637679459	661	38.79	23	660	15	601	1.0e-129	457	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
637679461	282	23.16	5	282	4	269	2.0e-09	56.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
637679462	312	33.11	22	303	1	294	3.0e-29	122	COG3391	DNA-binding beta-propeller fold protein YncE	381
637679463	177	41.01	1	173	3	180	3.0e-28	118	COG3038	Cytochrome b561	181
637679464	497	29.85	154	487	20	336	2.0e-36	147	COG0642	Signal transduction histidine kinase	336
637679465	112	48.51	10	110	6	104	4.0e-17	79.8	COG4654	Cytochrome c551/c552	110
637679466	123	57.52	1	113	3	114	9.0e-39	152	COG3564	Uncharacterized conserved protein, DUF779 family	116
637679467	506	45.17	19	500	1	471	0.0e+00	492	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
637679468	655	32.37	202	504	27	326	2.0e-40	160	COG0642	Signal transduction histidine kinase	336
637679469	597	21.86	30	401	108	470	1.0e-22	101	COG5184	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	476
637679474	523	22.49	69	476	12	361	7.0e-18	85.6	COG2814	Predicted arabinose efflux permease, MFS family	394
637679475	778	47.49	24	740	4	736	0.0e+00	804	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
637679476	679	38.26	28	664	4	599	4.0e-119	422	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
637679477	715	31.26	10	712	4	672	0.0e+00	463	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
637679478	774	30.41	50	663	3	556	0.0e+00	518	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
637679479	167	54.88	2	165	3	164	1.0e-64	238	COG4647	Acetone carboxylase, gamma subunit	165
637679480	463	58.45	1	219	1	218	2.0e-82	300	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
637679480	463	61.71	242	463	8	224	4.0e-81	295	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
637679481	125	29.91	9	124	5	104	1.0e-07	49	COG4654	Cytochrome c551/c552	110
637679482	593	28	9	590	112	752	2.0e-107	383	COG4993	Glucose dehydrogenase	773
637679484	256	27.46	7	143	4	145	2.0e-08	52.7	COG5501	Predicted secreted protein	148
637679485	312	23.08	57	270	30	244	3.0e-15	76	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
637679487	769	16.83	11	766	29	768	1.0e-27	118	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
637679489	215	45.24	9	215	2	211	3.0e-43	168	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
637679490	298	27.54	1	272	4	261	2.0e-12	66.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
637679493	215	40.65	1	213	5	215	1.0e-47	182	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
637679495	245	28.44	25	233	1	210	5.0e-27	114	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
637679498	338	22.66	67	320	17	291	2.0e-10	60.2	COG4974	Site-specific recombinase XerD	300
637679505	320	38.81	27	311	12	295	5.0e-61	228	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
637679506	726	21.77	29	724	47	768	1.0e-42	168	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
637679509	247	31.55	31	235	7	212	4.0e-33	134	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
637679510	471	37.84	27	461	7	416	4.0e-110	391	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
637679511	223	50.22	1	221	1	223	3.0e-32	131	COG2836	Sulfite exporter TauE/SafE	232
637679512	141	32.43	1	141	6	151	1.0e-13	68.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
637679513	735	51.86	11	724	4	713	0.0e+00	726	COG2217	Cation transport ATPase	713
637679515	68	42.65	1	68	1	68	1.0e-10	58.1	COG2608	Copper chaperone CopZ	71
637679516	348	47.7	1	348	1	346	2.0e-98	352	COG0709	Selenophosphate synthase	346
637679517	720	30.43	26	720	18	750	1.0e-106	380	COG4774	Outer membrane receptor for monomeric catechols	750
637679518	337	27.92	39	335	1	297	1.0e-42	167	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
637679519	381	27.51	6	379	6	365	5.0e-26	112	COG3490	Uncharacterized protein	366
637679520	67	56.86	1	51	1	51	3.0e-08	50.3	COG2906	Bacterioferritin-associated ferredoxin	63
637679523	160	61.78	1	157	1	156	1.0e-49	188	COG2193	Bacterioferritin (cytochrome b1)	157
637679524	161	52.87	1	157	1	156	4.0e-44	170	COG2193	Bacterioferritin (cytochrome b1)	157
637679525	470	40	1	466	3	453	6.0e-103	368	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
637679527	201	26.14	26	201	34	207	1.0e-19	90	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
637679528	451	35.43	24	393	1	361	1.0e-60	227	COG0348	Polyferredoxin	386
637679530	649	30.08	11	647	6	651	1.0e-111	397	COG0370	Fe2+ transport system protein B	653
637679531	402	22.28	7	398	5	393	2.0e-09	57.1	COG2814	Predicted arabinose efflux permease, MFS family	394
637679532	331	42.12	24	330	15	320	2.0e-72	266	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
637679533	891	21.94	711	862	14	151	2.0e-08	55.7	COG0835	Chemotaxis signal transduction protein	165
637679535	269	22.11	10	268	25	298	5.0e-17	82	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
637679536	261	45.02	3	250	18	263	4.0e-69	254	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
637679537	136	37.84	5	114	1	111	8.0e-13	66.3	COG1950	Uncharacterized membrane protein YvlD, DUF360 family	120
637679538	214	27.14	1	191	1	197	4.0e-22	98.1	COG2135	Putative SOS response-associated peptidase YedK	226
637679539	403	25.38	2	395	3	387	2.0e-34	140	COG2814	Predicted arabinose efflux permease, MFS family	394
637679540	154	25.42	30	143	29	135	3.0e-06	45	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
637679541	230	44.05	6	229	1	226	3.0e-57	215	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
637679542	902	54.09	5	894	5	889	0.0e+00	999	COG2205	K+-sensing histidine kinase KdpD	890
637679543	321	37.27	3	321	3	322	2.0e-63	236	COG0598	Mg2+ and Co2+ transporter CorA	322
637679545	188	31.08	39	184	2	149	5.0e-25	107	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
637679547	191	58.73	1	188	1	189	4.0e-65	240	COG2156	K+-transporting ATPase, c chain	190
637679548	688	71.7	2	688	1	681	0.0e+00	1030	COG2216	High-affinity K+ transport system, ATPase chain B	681
637679549	592	60.74	2	588	1	560	0.0e+00	729	COG2060	K+-transporting ATPase, A chain	560
637679551	218	27.36	12	204	11	211	9.0e-22	97.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
637679552	160	60.62	1	160	1	160	3.0e-71	260	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
637679556	215	27.64	19	212	32	220	2.0e-28	119	COG1418	HD superfamily phosphodieaserase, includes HD domain of RNase Y	222
637679558	399	23.96	12	395	14	390	3.0e-24	106	COG2814	Predicted arabinose efflux permease, MFS family	394
637679559	334	27.52	34	317	22	316	2.0e-37	149	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
637679560	305	30.38	5	291	4	292	9.0e-06	44.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
637679561	360	39.57	1	359	3	359	4.0e-86	311	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
637679562	194	24.19	1	186	6	189	2.0e-12	65.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
637679564	240	27.5	44	237	32	220	4.0e-29	121	COG1418	HD superfamily phosphodieaserase, includes HD domain of RNase Y	222
637679570	593	21.75	162	589	94	574	5.0e-21	96.3	COG3972	Superfamily I DNA and RNA helicases	660
637679572	267	27.93	3	260	9	298	2.0e-20	93.1	COG0672	High-affinity Fe2+/Pb2+ permease	383
637679575	181	52.75	1	177	1	179	3.0e-56	210	COG3470	Uncharacterized protein probably involved in high-affinity Fe2+ transport	179
637679576	141	36.69	1	139	1	137	3.0e-32	130	COG0848	Biopolymer transport protein ExbD	137
637679577	247	35.71	14	222	1	209	1.0e-33	137	COG0811	Biopolymer transport protein ExbB/TolQ	216
637679579	58	35	1	58	4	63	2.0e-06	44.2	COG4256	Hemin uptake protein HemP	63
637679580	606	41.44	3	480	26	505	4.0e-123	435	COG0513	Superfamily II DNA and RNA helicase	513
637679581	264	53.03	1	262	1	264	4.0e-77	281	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
637679582	348	42.82	5	348	2	316	6.0e-80	291	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
637679584	212	32.09	4	211	3	217	2.0e-28	118	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
637679585	335	36.86	10	335	4	326	4.0e-64	238	COG0306	Phosphate/sulfate permease	326
637679586	73	42.65	6	73	1	67	8.0e-07	45.4	COG5481	Uncharacterized protein	67
637679588	185	43.14	31	182	1	151	9.0e-33	133	COG0782	Transcription elongation factor, GreA/GreB family	151
637679594	636	60.86	8	630	1	618	0.0e+00	828	COG0326	Molecular chaperone, HSP90 family	623
637679596	466	37.13	1	466	21	494	2.0e-105	376	COG0513	Superfamily II DNA and RNA helicase	513
637679597	446	25.99	16	440	10	428	4.0e-56	212	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
637679599	181	21.37	19	135	4	115	8.0e-07	46.9	COG0727	Fe-S-cluster containining protein	132
637679601	180	26.22	8	159	55	216	3.0e-20	91.7	COG1451	Predicted metal-dependent hydrolase	223
637679602	388	25.98	28	380	38	379	6.0e-08	52.5	COG2814	Predicted arabinose efflux permease, MFS family	394
637679603	306	32	3	297	4	297	2.0e-33	136	COG0583	DNA-binding transcriptional regulator, LysR family	297
637679604	250	28.63	1	250	1	254	2.0e-10	59.6	COG0730	Uncharacterized membrane protein YfcA	258
637679605	70	50	1	70	1	70	5.0e-22	95.8	COG3530	Uncharacterized conserved protein, DUF3820 family	71
637679607	418	24.34	66	368	115	407	3.0e-20	93.5	COG0840	Methyl-accepting chemotaxis protein	408
637679608	101	25.88	1	85	8	92	5.0e-06	42.9	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
637679609	741	36.47	1	724	6	715	0.0e+00	549	COG0643	Chemotaxis protein histidine kinase CheA	716
637679610	541	34.07	130	498	1	408	3.0e-38	153	COG0840	Methyl-accepting chemotaxis protein	408
637679611	184	38.26	22	170	19	163	9.0e-33	133	COG0835	Chemotaxis signal transduction protein	165
637679612	197	43.45	20	162	14	157	8.0e-36	143	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
637679613	270	38.01	9	269	1	265	6.0e-65	240	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
637679614	170	30.82	9	165	8	164	2.0e-26	111	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
637679615	359	47.19	4	358	1	345	8.0e-98	350	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
637679618	622	41.68	124	618	16	500	0.0e+00	491	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
637679622	210	59.33	1	209	1	209	2.0e-85	308	COG0177	Endonuclease III	211
637679624	357	36.63	46	334	47	345	7.0e-75	274	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
637679625	230	49.77	5	214	1	212	1.0e-53	203	COG4660	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfE subunit	212
637679626	222	42.71	14	212	5	195	3.0e-42	165	COG4659	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit	195
637679627	338	49.55	5	334	6	334	5.0e-84	304	COG4658	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfD subunit	338
637679628	570	45.86	4	529	3	528	0.0e+00	483	COG4656	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfC subunit	529
637679629	180	56.91	1	177	4	184	1.0e-54	205	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
637679630	194	60.42	1	192	1	192	1.0e-60	226	COG4657	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfA subunit	193
637679631	347	46.58	45	345	2	294	3.0e-85	308	COG0167	Dihydroorotate dehydrogenase	310
637679632	462	33.09	56	459	41	455	3.0e-40	159	COG1538	Outer membrane protein TolC	457
637679633	412	29.45	1	305	5	310	9.0e-27	114	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
637679634	235	47.79	5	228	1	226	2.0e-75	275	COG1136	ABC-type lipoprotein export system, ATPase component	226
637679635	406	31.19	17	406	1	419	2.0e-35	143	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
637679636	419	22.49	24	356	2	338	4.0e-24	106	COG1252	NADH dehydrogenase, FAD-containing subunit	405
637679637	472	27.14	15	219	42	236	2.0e-13	70.8	COG3063	Tfp pilus assembly protein PilF	250
637679638	256	22.09	1	254	1	256	3.0e-23	102	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
637679639	404	43.1	1	404	1	412	2.0e-97	349	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
637679641	272	23.89	13	257	20	242	3.0e-20	92.2	COG1647	Esterase/lipase	243
637679642	148	21.77	26	148	39	161	4.0e-09	54.2	COG4731	Uncharacterized conserved protein, DUF2147 family	162
637679643	429	24.25	46	424	45	443	6.0e-21	95.6	COG1538	Outer membrane protein TolC	457
637679644	397	27.71	59	386	28	356	5.0e-19	89	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
637679645	1033	42.08	1	1030	1	1026	0.0e+00	931	COG3696	Cu/Ag efflux pump CusA	1027
637679646	205	28.63	1	203	1	223	4.0e-23	101	COG3416	Uncharacterized protein	233
637679647	221	44.3	1	220	1	227	8.0e-50	190	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
637679648	469	29.84	161	464	35	336	3.0e-39	156	COG0642	Signal transduction histidine kinase	336
637679649	167	36.36	1	165	1	144	9.0e-27	113	COG3019	Uncharacterized conserved protein	149
637679651	621	57.46	1	621	7	627	0.0e+00	784	COG3158	K+ transporter	627
637679652	92	43.96	1	89	1	91	4.0e-20	89.5	COG1254	Acylphosphatase	92
637679654	180	26.45	1	152	4	154	9.0e-22	96.6	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
637679656	281	45.32	5	281	8	271	1.0e-48	187	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
637679657	201	48.91	9	192	10	185	3.0e-55	208	COG1704	Uncharacterized conserved protein	185
637679658	149	39.47	1	149	12	159	5.0e-26	110	COG2030	Acyl dehydratase	159
637679659	314	35.58	9	266	42	303	3.0e-31	129	COG2843	Poly-gamma-glutamate biosynthesis protein CapA/YwtB (capsule formation), metallophosphatase superfamily	372
637679661	228	32.85	91	225	16	151	5.0e-15	74.7	COG3126	Uncharacterized lipoprotein YbaY	158
637679662	247	48.95	9	241	5	243	2.0e-76	279	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
637679663	234	50.47	11	222	3	213	1.0e-73	269	COG2360	Leu/Phe-tRNA-protein transferase	221
637679664	359	41.39	1	353	3	352	4.0e-103	368	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
637679665	545	33.7	9	544	12	537	2.0e-77	283	COG1178	ABC-type Fe3+ transport system, permease component	540
637679667	337	27.24	39	337	1	299	2.0e-39	156	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
637679668	169	34.55	3	163	36	197	4.0e-31	127	COG0791	Cell wall-associated hydrolase, NlpC family	197
637679669	331	31.02	4	328	1	326	2.0e-50	193	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
637679671	630	36.14	45	614	1	528	0.0e+00	529	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
637679672	512	40.49	18	497	5	492	1.0e-114	407	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
637679673	368	36.09	100	365	4	267	2.0e-51	196	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
637679674	251	52.63	1	247	3	249	6.0e-81	293	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
637679675	308	23.82	1	308	1	312	9.0e-25	107	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
637679677	207	20.97	17	202	1	184	5.0e-10	57.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
637679678	249	49.62	1	249	1	260	9.0e-71	260	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
637679679	310	54.89	1	310	1	311	7.0e-83	300	COG2025	Electron transfer flavoprotein, alpha subunit	313
637679680	221	33.51	31	218	28	215	6.0e-23	101	COG3235	Uncharacterized membrane protein	223
637679682	593	35.12	35	460	6	392	7.0e-69	255	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
637679683	127	49.09	2	110	1	110	4.0e-37	146	COG0360	Ribosomal protein S6	112
637679684	94	34.21	1	75	19	94	1.0e-11	61.5	COG2965	Primosomal replication protein N	103
637679685	91	60.27	12	84	3	75	2.0e-18	84.5	COG0238	Ribosomal protein S18	75
637679686	148	55.41	1	148	1	147	4.0e-41	160	COG0359	Ribosomal protein L9	148
637679687	469	53.39	19	460	1	434	0.0e+00	547	COG0305	Replicative DNA helicase	435
637679689	475	49.57	13	475	1	436	0.0e+00	520	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
637679690	162	53.33	13	162	6	155	5.0e-52	196	COG1225	Peroxiredoxin	157
637679691	734	21.4	17	689	3	561	4.0e-39	156	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
637679693	222	38.46	1	218	3	220	2.0e-40	159	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
637679694	232	59.83	1	230	9	241	1.0e-86	312	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
637679695	219	31.79	46	218	27	190	9.0e-26	110	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
637679696	444	38.72	9	420	3	414	8.0e-86	311	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
637679697	879	56.91	1	844	1	803	0.0e+00	1057	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
637679698	361	56.63	1	359	3	363	0.0e+00	480	COG1932	Phosphoserine aminotransferase	365
637679699	363	45.26	2	95	3	96	7.0e-19	88.5	COG1605	Chorismate mutase	101
637679699	363	51.09	93	361	2	275	2.0e-92	332	COG0077	Prephenate dehydratase	279
637679700	362	43.25	7	362	2	352	1.0e-89	323	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
637679701	289	40.14	4	285	3	279	4.0e-66	244	COG0287	Prephenate dehydrogenase	279
637679702	279	23.24	3	279	95	419	8.0e-23	100	COG1793	ATP-dependent DNA ligase	444
637679703	334	45.07	2	333	3	329	0.0e+00	478	COG1087	UDP-glucose 4-epimerase	329
637679704	354	63.74	1	352	1	340	0.0e+00	553	COG1088	dTDP-D-glucose 4,6-dehydratase	340
637679705	296	60.21	5	293	1	286	2.0e-121	429	COG1209	dTDP-glucose pyrophosphorylase	286
637679706	177	62.13	1	169	1	165	7.0e-60	223	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
637679708	392	41.86	3	387	5	372	5.0e-108	384	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
637679710	312	25.6	23	291	15	298	6.0e-24	105	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
637679711	675	31.71	246	651	8	431	1.0e-69	257	COG0001	Glutamate-1-semialdehyde aminotransferase	432
637679711	675	37.66	1	227	2	229	1.0e-57	218	COG1861	Spore coat polysaccharide biosynthesis protein SpsF, cytidylyltransferase family	241
637679712	359	24.72	1	353	1	318	1.0e-39	157	COG3980	Spore coat polysaccharide biosynthesis protein SpsG, predicted glycosyltransferase	318
637679713	418	25.71	3	167	12	186	5.0e-18	85.8	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
637679714	348	50.14	2	346	1	346	4.0e-118	417	COG2089	Sialic acid synthase SpsE, contains C-terminal SAF domain	347
637679715	223	28.27	3	190	11	200	3.0e-23	102	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
637679717	512	20.53	1	487	3	477	1.0e-17	84.8	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
637679720	398	28.45	57	391	38	375	6.0e-33	135	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
637679721	325	33.67	20	308	8	306	5.0e-39	155	COG0451	Nucleoside-diphosphate-sugar epimerase	314
637679723	365	24.47	12	337	2	314	1.0e-34	140	COG0451	Nucleoside-diphosphate-sugar epimerase	314
637679724	158	20.78	9	157	8	159	9.0e-13	66.5	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
637679725	310	26.32	1	296	1	299	8.0e-26	111	COG0451	Nucleoside-diphosphate-sugar epimerase	314
637679726	309	22.81	19	301	1	273	1.0e-19	90.6	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
637679727	402	25.06	21	400	3	381	2.0e-30	127	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
637679728	405	24.37	91	401	72	381	2.0e-24	107	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
637679729	284	28.72	1	280	1	276	1.0e-45	176	COG1091	dTDP-4-dehydrorhamnose reductase	281
637679731	372	35.77	1	371	3	383	1.0e-99	356	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
637679732	396	19.55	1	396	1	376	1.0e-20	94.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
637679733	373	27.27	12	295	8	284	8.0e-31	128	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
637679734	429	25.53	6	427	7	421	6.0e-17	82.5	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
637679736	307	30.5	1	277	4	275	1.0e-37	150	COG1216	Glycosyltransferase, GT2 family	305
637679737	359	20	1	353	3	381	2.0e-15	77	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
637679738	650	28.34	1	625	1	519	1.0e-93	337	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
637679739	387	25.41	27	383	31	381	1.0e-28	120	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
637679740	186	40.32	1	184	40	225	1.0e-53	202	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
637679741	617	46.42	20	573	3	539	0.0e+00	563	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
637679742	643	44.89	13	425	14	426	6.0e-119	421	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
637679742	643	54.75	424	642	1	221	6.0e-69	255	COG0283	Cytidylate kinase	222
637679743	559	57.2	1	541	2	534	0.0e+00	601	COG0539	Ribosomal protein S1	541
637679744	94	51.61	1	93	2	93	3.0e-27	113	COG0776	Bacterial nucleoid DNA-binding protein	94
637679745	96	32.88	9	81	27	98	1.0e-08	51.4	COG5416	Uncharacterized integral membrane protein	98
637679746	390	42.67	10	385	6	387	1.0e-105	376	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
637679747	439	53.88	1	425	1	414	0.0e+00	556	COG1004	UDP-glucose 6-dehydrogenase	414
637679749	332	27.43	1	331	1	311	3.0e-39	155	COG0451	Nucleoside-diphosphate-sugar epimerase	314
637679750	299	51.32	1	294	1	300	3.0e-102	364	COG0031	Cysteine synthase	300
637679751	261	35.91	1	181	1	131	5.0e-24	105	COG3298	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	164
637679752	182	53.14	1	175	1	171	2.0e-55	208	COG0221	Inorganic pyrophosphatase	171
637679753	538	31.6	1	244	2	249	8.0e-39	155	COG0388	Predicted amidohydrolase	274
637679753	538	42.7	256	527	5	268	2.0e-70	260	COG0171	NH3-dependent NAD+ synthetase	268
637679754	112	75	1	112	1	112	1.0e-40	158	COG0347	Nitrogen regulatory protein PII	112
637679755	256	37.85	77	253	9	184	3.0e-31	128	COG2840	DNA-nicking endonuclease, Smr domain	184
637679756	320	50.32	6	319	2	305	2.0e-92	333	COG0492	Thioredoxin reductase	305
637679757	220	34.29	12	217	1	210	1.0e-34	139	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
637679759	208	35.24	2	206	1	208	1.0e-37	149	COG2834	Outer membrane lipoprotein-sorting protein	211
637679760	192	26.67	1	189	7	201	2.0e-41	162	COG1573	Uracil-DNA glycosylase	202
637679761	437	57.31	11	436	9	436	0.0e+00	565	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
637679763	427	60.14	1	424	1	425	0.0e+00	592	COG0172	Seryl-tRNA synthetase	429
637679764	511	34.69	35	470	25	459	1.0e-80	294	COG4623	Membrane-bound lytic murein transglycosylase MltF	473
637679767	529	29.79	17	522	2	488	7.0e-76	278	COG0286	Type I restriction-modification system, DNA methylase subunit	489
637679768	275	30.35	66	265	36	224	2.0e-15	76.6	COG2801	Transposase InsO and inactivated derivatives	232
637679771	1077	28.79	14	1035	1	962	0.0e+00	489	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
637679774	273	40	1	60	2	61	6.0e-10	58.3	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
637679775	187	40.39	4	186	2	202	1.0e-26	112	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
637679779	325	34.34	1	325	1	316	3.0e-51	195	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
637679780	468	38.11	223	466	62	285	1.0e-46	180	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
637679781	658	47.91	1	596	6	531	0.0e+00	599	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
637679789	464	42.34	1	464	7	470	0.0e+00	489	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
637679791	84	30.77	1	78	2	73	3.0e-10	56.8	COG3655	DNA-binding transcriptional regulator, XRE family	73
637679793	411	19.53	96	386	13	297	2.0e-08	54.2	COG0582	Integrase	309
637679796	113	41.94	10	102	1	93	4.0e-24	103	COG0776	Bacterial nucleoid DNA-binding protein	94
637679798	400	29.69	275	400	1	126	3.0e-18	86.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
637679799	278	31.18	13	272	6	279	2.0e-26	113	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
637679800	178	37.42	9	171	41	198	2.0e-28	118	COG5631	Predicted transcription regulator, contains HTH domain, MarR family	199
637679801	161	24.44	17	145	2	134	7.0e-12	63.4	COG2703	Hemerythrin	144
637679804	250	29.06	3	233	1	230	8.0e-26	110	COG4126	Asp/Glu/hydantoin racemase	230
637679805	510	36.59	36	505	7	474	2.0e-86	313	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
637679806	373	20	2	322	59	373	3.0e-13	69.8	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
637679807	211	25	1	207	3	202	1.0e-21	96.6	COG0778	Nitroreductase	207
637679808	147	42.42	15	146	8	139	3.0e-24	104	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
637679809	97	32.26	3	95	2	94	1.0e-15	74.6	COG1359	Quinol monooxygenase YgiN	100
637679810	330	35.29	212	330	8	124	1.0e-13	70.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
637679813	174	34.42	15	163	5	157	2.0e-27	115	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
637679814	391	20.32	9	391	10	440	4.0e-26	112	COG2067	Long-chain fatty acid transport protein	440
637679816	374	30.85	8	361	3	326	4.0e-45	175	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
637679818	790	20.44	1	771	1	726	6.0e-63	236	COG1033	Predicted exporter protein, RND superfamily	727
637679822	262	45.91	7	262	6	262	5.0e-66	244	COG3971	2-keto-4-pentenoate hydratase	264
637679823	304	54.22	1	294	1	305	4.0e-96	344	COG4569	Acetaldehyde dehydrogenase (acetylating)	310
637679824	341	22.62	6	330	1	334	3.0e-43	169	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
637679825	250	38.34	4	248	2	251	1.0e-45	176	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
637679826	451	21.43	19	416	2	367	1.0e-23	104	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
637679827	349	27.66	10	100	1	92	3.0e-09	56.2	COG0633	Ferredoxin	102
637679827	349	28.27	114	348	3	233	5.0e-34	138	COG1018	Ferredoxin-NADP reductase	266
637679828	466	40.93	4	464	2	475	5.0e-109	388	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
637679829	298	29.24	30	294	10	282	2.0e-30	126	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
637679831	544	35.26	231	542	98	406	4.0e-49	189	COG0840	Methyl-accepting chemotaxis protein	408
637679840	341	30.46	6	328	3	303	9.0e-37	147	COG3547	Transposase	303
637679847	199	37.77	11	193	10	197	3.0e-38	151	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
637679850	212	25.25	4	194	1	199	7.0e-16	77.6	COG0625	Glutathione S-transferase	211
637679852	216	27.66	7	132	5	143	2.0e-16	79.2	COG0328	Ribonuclease HI	154
637679856	67	64.18	1	67	1	67	6.0e-26	109	COG1278	Cold shock protein, CspA family	67
637679857	309	29.1	14	200	19	207	8.0e-23	101	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
637679857	309	30.3	207	302	5	101	1.0e-05	44.1	COG0607	Rhodanese-related sulfurtransferase	110
637679858	304	40.5	23	296	5	275	1.0e-66	246	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
637679859	199	46.27	1	198	2	202	7.0e-55	206	COG1182	FMN-dependent NADH-azoreductase	202
637679860	303	35.45	7	301	1	292	1.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
637679865	258	54.36	18	212	4	193	6.0e-65	240	COG1045	Serine acetyltransferase	194
637679866	378	41.69	6	364	3	368	3.0e-90	325	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
637679867	683	34.46	411	677	102	365	6.0e-44	172	COG4585	Signal transduction histidine kinase	365
637679868	216	39.05	4	212	1	210	8.0e-47	180	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
637679869	116	29.9	19	115	12	108	1.0e-06	45.1	COG4654	Cytochrome c551/c552	110
637679872	655	18.33	383	622	1	218	8.0e-06	46	COG2864	Cytochrome b subunit of formate dehydrogenase	218
637679873	399	29.08	4	281	3	279	2.0e-30	126	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
637679874	134	30.23	7	134	5	132	2.0e-09	55.4	COG2703	Hemerythrin	144
637679880	80	35.82	9	75	3	66	8.0e-06	41.9	COG5554	Nitrogen fixation protein	69
637679881	522	30.02	34	509	3	444	3.0e-82	299	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
637679882	490	35.86	22	487	1	456	1.0e-96	347	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
637679883	296	71.94	4	281	1	278	1.0e-124	439	COG1348	Nitrogenase subunit NifH, an ATPase	278
637679888	125	27.91	2	124	4	131	7.0e-11	59.6	COG2703	Hemerythrin	144
637679889	122	19.64	3	114	1	104	5.0e-07	46.9	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
637679892	201	54.46	1	201	9	202	5.0e-65	240	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
637679893	228	36.24	1	228	1	229	1.0e-46	179	COG0830	Urease accessory protein UreF	229
637679894	175	46.9	3	147	11	150	2.0e-29	122	COG2371	Urease accessory protein UreE	155
637679895	569	79.19	5	569	3	568	0.0e+00	1031	COG0804	Urease alpha subunit	568
637679896	101	69.31	1	101	1	101	1.0e-42	164	COG0832	Urease beta subunit	106
637679897	100	77.78	1	99	1	99	9.0e-44	168	COG0831	Urease gamma subunit	100
637679898	288	38.85	11	286	1	269	8.0e-67	247	COG0829	Urease accessory protein UreH	269
637679901	386	45.4	63	386	8	318	3.0e-84	305	COG2826	Transposase and inactivated derivatives, IS30 family	318
637679902	230	51.11	1	222	3	227	1.0e-85	309	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
637679903	278	67.36	37	278	5	246	8.0e-105	373	COG4674	ABC-type uncharacterized transport system, ATPase component	249
637679904	371	32.52	43	365	20	314	1.0e-50	193	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
637679905	525	40.07	233	522	10	295	1.0e-60	227	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
637679908	398	27.37	6	357	4	354	9.0e-45	174	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637679909	794	34.15	357	639	63	335	2.0e-40	161	COG0642	Signal transduction histidine kinase	336
637679910	147	52.03	1	147	4	151	2.0e-49	188	COG1513	Cyanate lyase	151
637679911	420	32.89	23	396	4	366	2.0e-69	256	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637679912	545	61.08	25	543	3	520	0.0e+00	666	COG0033	Phosphoglucomutase	524
637679913	308	44.07	244	302	2	60	3.0e-11	63.1	COG2771	DNA-binding transcriptional regulator, CsgD family	65
637679914	1131	28.79	577	904	11	335	4.0e-45	177	COG0642	Signal transduction histidine kinase	336
637679915	326	28.57	25	300	2	301	1.0e-34	140	COG1397	ADP-ribosylglycohydrolase	314
637679917	120	25.23	11	116	9	96	8.0e-08	49.3	COG0633	Ferredoxin	102
637679918	95	31.87	1	89	1	91	6.0e-10	55.8	COG0633	Ferredoxin	102
637679919	423	40.6	8	406	2	388	2.0e-109	389	COG0426	Flavorubredoxin	388
637679920	159	27.19	4	115	3	116	9.0e-10	56.3	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
637679922	500	18.83	45	417	6	320	3.0e-25	110	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
637679925	186	29.61	1	178	1	151	2.0e-20	92.4	COG0716	Flavodoxin	151
637679926	108	34.44	13	99	9	98	3.0e-12	63.8	COG0607	Rhodanese-related sulfurtransferase	110
637679930	348	33.33	2	325	19	313	6.0e-35	141	COG1612	Heme A synthase	323
637679931	298	46.85	13	298	16	301	5.0e-72	264	COG0109	Polyprenyltransferase (heme O synthase)	304
637679933	228	28.76	7	226	18	240	5.0e-31	128	COG3346	Cytochrome oxidase assembly protein ShyY1	252
637679935	290	34.05	59	290	4	206	2.0e-36	146	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
637679936	203	38.71	9	189	8	178	3.0e-47	181	COG3175	Cytochrome c oxidase assembly protein Cox11	195
637679938	531	52.68	14	530	1	517	0.0e+00	517	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
637679939	401	23.94	265	401	16	144	1.0e-08	54.6	COG2010	Cytochrome c, mono- and diheme variants	150
637679939	401	29.89	26	284	2	231	6.0e-51	195	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
637679940	192	43.92	5	191	17	205	1.0e-42	166	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
637679941	101	35.64	1	101	2	98	3.0e-18	83.1	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
637679943	281	32.72	3	271	2	269	6.0e-47	181	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
637679944	248	29.53	1	246	4	255	3.0e-40	158	COG0725	ABC-type molybdate transport system, periplasmic component	258
637679945	272	42.54	7	140	2	130	3.0e-28	119	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
637679945	272	45.59	203	270	1	68	2.0e-11	63	COG3585	Molybdopterin-binding protein	69
637679946	142	46.27	74	140	2	68	3.0e-11	61.5	COG3585	Molybdopterin-binding protein	69
637679951	177	33.9	1	175	1	151	5.0e-24	104	COG0716	Flavodoxin	151
637679953	109	50	51	104	4	57	6.0e-13	66.1	COG3411	(2Fe-2S) ferredoxin	64
637679955	549	39.85	25	549	17	550	9.0e-127	447	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
637679956	531	23.62	279	524	81	327	4.0e-20	92.9	COG0642	Signal transduction histidine kinase	336
637679957	229	40.62	34	221	3	193	4.0e-43	167	COG4659	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit	195
637679958	224	47.34	4	210	2	208	1.0e-55	209	COG4660	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfE subunit	212
637679959	180	28.38	26	173	6	144	1.0e-17	83	COG3086	Positive regulator of sigma E activity	150
637679960	193	56.32	1	190	1	190	3.0e-52	198	COG4657	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfA subunit	193
637679961	177	42.37	1	173	4	180	4.0e-39	154	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
637679962	503	41.22	14	501	9	496	2.0e-116	413	COG4656	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfC subunit	529
637679963	357	42.82	9	349	5	338	4.0e-74	272	COG4658	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfD subunit	338
637679964	90	40.48	1	84	4	87	2.0e-17	80.7	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
637679965	380	47.35	4	362	1	356	3.0e-94	338	COG3288	NAD/NADP transhydrogenase alpha subunit	356
637679967	456	42.4	7	452	6	463	6.0e-114	404	COG1282	NAD/NADP transhydrogenase beta subunit	463
637679968	370	32.79	253	370	28	149	7.0e-08	52	COG1555	DNA uptake protein ComE and related DNA-binding proteins	149
637679969	466	33.63	14	454	14	449	1.0e-85	310	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
637679973	467	26.43	8	447	24	452	5.0e-61	229	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
637679975	155	29.51	5	123	1	122	4.0e-14	71.1	COG3086	Positive regulator of sigma E activity	150
637679981	107	43.93	1	107	4	110	1.0e-31	127	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
637679982	298	34.57	214	290	3	83	9.0e-11	61.1	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
637679982	298	41.84	2	123	5	143	2.0e-27	116	COG0822	NifU homolog involved in Fe-S cluster formation	150
637679983	404	52.59	4	386	1	385	0.0e+00	495	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
637679986	263	32.92	31	262	1	243	1.0e-51	196	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
637679987	201	39.7	8	201	19	216	5.0e-35	140	COG4117	Thiosulfate reductase cytochrome b subunit	221
637679988	190	30.73	17	190	2	179	5.0e-20	90.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
637679989	205	40.2	2	205	10	213	2.0e-32	131	COG4944	Uncharacterized protein	213
637679990	156	71.9	4	156	2	154	1.0e-61	228	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
637679991	205	26.63	7	174	4	167	2.0e-19	89.3	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
637679992	180	28	5	172	2	176	2.0e-14	72.1	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
637679993	313	34.8	3	293	2	292	2.0e-36	146	COG0583	DNA-binding transcriptional regulator, LysR family	297
637679994	327	31.93	2	325	1	326	2.0e-51	196	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
637679995	212	23.68	23	210	12	201	5.0e-11	61.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
637679996	298	26.94	4	298	1	295	7.0e-25	108	COG0583	DNA-binding transcriptional regulator, LysR family	297
637680004	258	31.34	1	255	2	266	5.0e-51	194	COG1018	Ferredoxin-NADP reductase	266
637680005	307	28.23	3	291	1	290	6.0e-32	131	COG0583	DNA-binding transcriptional regulator, LysR family	297
637680008	127	14.68	13	120	11	119	2.0e-08	51.4	COG1539	Dihydroneopterin aldolase	121
637680009	185	33.55	7	149	1	151	7.0e-20	90.4	COG0262	Dihydrofolate reductase	167
637680011	238	23.63	5	186	9	184	6.0e-10	58.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
637680012	784	28.24	89	470	18	382	9.0e-45	175	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
637680013	435	35.5	12	431	4	388	2.0e-70	260	COG0183	Acetyl-CoA acetyltransferase	392
637680014	315	23.89	1	310	1	281	2.0e-31	129	COG1307	Fatty acid-binding protein DegV (function unknown)	282
637680015	637	37.79	301	587	4	302	3.0e-63	237	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
637680015	637	39.29	10	199	8	200	1.0e-33	138	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
637680016	442	34.32	12	442	11	440	6.0e-76	278	COG2067	Long-chain fatty acid transport protein	440
637680017	799	33.77	6	304	3	293	2.0e-60	228	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
637680018	399	39.07	6	397	2	390	3.0e-77	282	COG0183	Acetyl-CoA acetyltransferase	392
637680021	553	37.52	13	551	1	523	0.0e+00	467	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
637680022	315	32.02	1	310	3	332	4.0e-63	234	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
637680023	597	32	34	454	5	387	2.0e-66	247	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
637680026	203	28.57	55	199	51	187	1.0e-22	100	COG3672	Predicted transglutaminase-like cysteine proteinase	191
637680029	164	30.17	30	145	14	127	2.0e-12	65.7	COG0526	Thiol-disulfide isomerase or thioredoxin	127
637680032	284	32.3	1	248	4	257	1.0e-43	170	COG1131	ABC-type multidrug transport system, ATPase component	293
637680035	452	29.51	69	428	30	384	1.0e-47	184	COG3420	Nitrous oxidase accessory protein NosD, contains tandem CASH domains	408
637680037	241	29.9	141	237	18	111	5.0e-12	65	COG2863	Cytochrome c553	121
637680038	102	35	3	102	7	101	3.0e-15	73.5	COG2863	Cytochrome c553	121
637680039	760	33.01	49	641	56	637	3.0e-75	277	COG4263	Nitrous oxide reductase	637
637680040	218	39.52	2	211	1	210	8.0e-49	187	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
637680042	841	36.4	341	611	65	327	8.0e-42	166	COG0642	Signal transduction histidine kinase	336
637680043	760	33.01	49	641	56	637	3.0e-75	277	COG4263	Nitrous oxide reductase	637
637680045	200	39.6	1	200	8	207	3.0e-43	168	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
637680046	160	46.76	14	152	9	147	1.0e-29	122	COG2847	Copper(I)-binding protein	151
637680048	462	35.37	150	458	21	327	6.0e-42	165	COG0642	Signal transduction histidine kinase	336
637680049	223	43.42	1	220	1	227	1.0e-51	196	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
637680050	195	51.63	1	184	2	182	3.0e-52	197	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
637680052	126	46.96	13	124	17	129	2.0e-22	97.7	COG3474	Cytochrome c2	135
637680053	177	55.56	6	176	13	182	6.0e-50	190	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
637680055	220	37.62	1	100	1	97	2.0e-13	69.3	COG2863	Cytochrome c553	121
637680058	434	47.63	14	432	13	433	0.0e+00	475	COG1362	Aspartyl aminopeptidase	437
637680060	238	35.74	1	232	13	243	2.0e-45	175	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
637680061	148	63.89	7	147	4	147	1.0e-47	182	COG0328	Ribonuclease HI	154
637680063	265	29.27	6	217	18	248	2.0e-18	86.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
637680068	444	31.18	5	434	1	419	2.0e-65	243	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
637680070	790	28.82	8	321	2	332	1.0e-34	142	COG0515	Serine/threonine protein kinase	384
637680071	257	39.53	5	257	12	254	6.0e-61	227	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
637680072	318	51.54	17	306	2	289	2.0e-84	306	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
637680073	245	57.72	3	240	2	247	2.0e-77	282	COG1496	Copper oxidase (laccase) domain	249
637680074	255	31.74	34	254	40	265	6.0e-20	91.1	COG0428	Zinc transporter ZupT	266
637680076	593	50.34	144	590	5	445	0.0e+00	532	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
637680077	246	40	1	243	4	250	4.0e-49	188	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
637680078	247	41.83	1	244	3	250	1.0e-47	183	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
637680080	186	35.09	6	173	10	180	3.0e-37	148	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
637680081	873	34.32	455	724	70	329	2.0e-41	164	COG0642	Signal transduction histidine kinase	336
637680082	318	23.82	1	315	1	358	3.0e-29	122	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
637680083	274	66.18	5	274	8	282	8.0e-118	416	COG0447	1,4-Dihydroxy-2-naphthoyl-CoA synthase	282
637680084	160	41.54	1	127	1	130	8.0e-21	93.5	COG2703	Hemerythrin	144
637680087	556	49.73	4	554	1	550	0.0e+00	595	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
637680089	802	32.99	362	654	44	327	7.0e-41	163	COG0642	Signal transduction histidine kinase	336
637680090	425	28.19	201	348	34	180	3.0e-11	63.2	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
637680094	510	48.06	1	307	2	297	1.0e-105	377	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
637680094	510	55.06	320	497	1	178	6.0e-65	242	COG1838	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain	184
637680095	179	50	2	165	1	160	6.0e-37	146	COG2862	Uncharacterized membrane protein YqhA	169
637680096	654	45.04	69	642	1	528	0.0e+00	659	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
637680098	903	25.11	1	467	2	455	4.0e-52	200	COG0591	Na+/proline symporter	493
637680102	646	28.94	25	646	8	610	2.0e-107	383	COG2905	Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains	610
637680105	83	39.24	5	83	10	88	9.0e-15	71.9	COG4327	Uncharacterized membrane protein	101
637680112	302	30.2	3	296	1	294	2.0e-22	99.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
637680113	416	39.26	1	393	10	394	2.0e-89	323	COG0019	Diaminopimelate decarboxylase	394
637680116	73	47.83	5	73	26	94	2.0e-19	87.1	COG0776	Bacterial nucleoid DNA-binding protein	94
637680121	275	30.35	66	265	36	224	2.0e-15	76.6	COG2801	Transposase InsO and inactivated derivatives	232
637680125	342	37.13	27	328	7	300	7.0e-47	181	COG5377	Phage-related protein, predicted endonuclease	319
637680127	94	43.96	1	91	1	90	1.0e-22	97.9	COG0776	Bacterial nucleoid DNA-binding protein	94
637680128	128	31.36	5	121	8	125	1.0e-13	69.2	COG2703	Hemerythrin	144
637680134	652	28.27	322	649	19	333	8.0e-34	139	COG0642	Signal transduction histidine kinase	336
637680136	233	25.94	12	220	1	210	2.0e-26	112	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
637680137	133	28.46	4	125	2	123	2.0e-09	54.6	COG2703	Hemerythrin	144
637680138	234	44.89	6	229	2	224	5.0e-65	241	COG1136	ABC-type lipoprotein export system, ATPase component	226
637680139	397	16.71	14	397	2	418	1.0e-08	54.8	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
637680141	201	24.88	1	201	2	200	3.0e-09	55.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
637680142	419	21	89	404	1	309	1.0e-10	61.1	COG0582	Integrase	309
637680145	145	40.44	2	137	1	136	2.0e-21	95	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
637680146	395	49.1	11	393	17	398	3.0e-128	451	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
637680148	268	52.11	1	259	1	260	3.0e-74	271	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
637680149	254	48.39	6	253	1	241	2.0e-69	255	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
637680150	299	27.8	35	281	13	266	1.0e-22	100	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
637680151	717	19.26	4	717	12	768	2.0e-18	88.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
637680152	326	51.38	7	258	1	249	4.0e-86	311	COG1010	Precorrin-3B methylase	249
637680155	267	37.97	8	243	1	232	9.0e-40	157	COG2243	Precorrin-2 methylase	234
637680156	428	28.12	9	232	4	210	1.0e-27	118	COG2241	Precorrin-6B methylase 1	210
637680156	428	43.92	237	425	2	186	1.0e-44	174	COG2242	Precorrin-6B methylase 2	187
637680157	393	41.1	32	393	11	367	3.0e-73	269	COG1903	Cobalamin biosynthesis protein CbiD	367
637680158	225	42.03	14	219	8	209	1.0e-43	169	COG2082	Precorrin isomerase	210
637680159	303	31.82	7	246	5	236	1.0e-23	104	COG2138	Sirohydrochlorin ferrochelatase	245
637680160	269	47.27	1	256	1	252	1.0e-75	276	COG2875	Precorrin-4 methylase	254
637680161	291	44.68	4	237	2	235	2.0e-64	239	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
637680162	246	24.5	1	246	1	249	2.0e-13	69.3	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
637680163	116	39.81	1	102	2	94	9.0e-22	95.4	COG1930	ABC-type cobalt transport system, periplasmic component	97
637680164	225	45.07	1	213	1	203	3.0e-36	145	COG0310	ABC-type Co2+ transport system, permease component	204
637680165	320	24.91	15	295	6	265	5.0e-13	69	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
637680166	305	20.79	1	303	4	266	5.0e-16	79	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
637680167	231	36.56	3	227	4	229	5.0e-52	197	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
637680169	375	31.07	9	338	18	346	9.0e-44	171	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
637680170	335	22.15	15	327	14	319	5.0e-06	45.4	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
637680172	436	27.33	4	425	2	441	1.0e-74	274	COG1232	Protoporphyrinogen oxidase	444
637680173	309	24.52	1	230	1	257	1.0e-19	90.8	COG0451	Nucleoside-diphosphate-sugar epimerase	314
637680175	250	22.75	1	248	3	255	1.0e-27	116	COG0300	Short-chain dehydrogenase	265
637680176	432	20.56	31	411	53	433	4.0e-28	119	COG0277	FAD/FMN-containing dehydrogenase	459
637680177	503	29.01	210	494	12	287	1.0e-31	131	COG0382	4-hydroxybenzoate polyprenyltransferase	289
637680178	275	30.35	66	265	36	224	2.0e-15	76.6	COG2801	Transposase InsO and inactivated derivatives	232
637680183	90	58.89	1	90	2	91	8.0e-27	111	COG0776	Bacterial nucleoid DNA-binding protein	94
637680184	804	66.11	4	781	1	782	0.0e+00	1157	COG0466	ATP-dependent Lon protease, bacterial type	782
637680185	420	74.14	13	418	1	405	0.0e+00	700	COG1219	ATP-dependent protease Clp, ATPase subunit	408
637680186	209	76.8	16	209	3	196	2.0e-88	318	COG0740	ATP-dependent protease ClpP, protease subunit	200
637680187	434	38.91	1	434	1	441	9.0e-95	341	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
637680189	484	28.84	9	483	2	411	9.0e-68	251	COG2195	Di- or tripeptidase	414
637680192	299	40.52	12	279	2	257	4.0e-53	201	COG2890	Methylase of polypeptide chain release factors	280
637680193	377	36.11	1	374	11	406	4.0e-77	282	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
637680194	395	50.43	1	348	5	353	2.0e-113	402	COG5008	Tfp pilus assembly protein, ATPase PilU	375
637680195	272	50.91	5	271	4	269	8.0e-80	290	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
637680196	396	31.51	5	396	4	392	8.0e-74	271	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
637680200	157	45.24	1	125	5	129	1.0e-31	128	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
637680201	1167	33.11	1	1164	1	1163	0.0e+00	528	COG1196	Chromosome segregation ATPase	1163
637680203	683	57.82	1	678	1	666	0.0e+00	917	COG0272	NAD-dependent DNA ligase	667
637680204	289	61.72	1	289	1	289	3.0e-124	438	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
637680205	182	36	9	182	4	178	2.0e-49	188	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
637680207	256	42.34	1	244	18	260	4.0e-59	221	COG0005	Purine nucleoside phosphorylase	262
637680208	852	42.05	2	845	10	854	0.0e+00	820	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
637680209	266	53.88	1	255	1	252	5.0e-95	340	COG0024	Methionine aminopeptidase	255
637680210	320	49.83	18	314	1	281	4.0e-89	321	COG1091	dTDP-4-dehydrorhamnose reductase	281
637680211	248	58.75	3	242	4	242	1.0e-91	329	COG0052	Ribosomal protein S2	252
637680212	299	53.02	1	294	1	296	6.0e-79	287	COG0264	Translation elongation factor EF-Ts	296
637680213	238	61.02	2	236	1	236	2.0e-88	319	COG0528	Uridylate kinase	238
637680214	198	50.81	14	198	3	187	2.0e-60	225	COG0233	Ribosome recycling factor	187
637680215	253	53.88	15	243	14	245	2.0e-84	305	COG0020	Undecaprenyl pyrophosphate synthase	245
637680216	276	33.94	1	273	1	265	2.0e-27	116	COG0575	CDP-diglyceride synthetase	265
637680217	398	58.27	6	397	2	385	0.0e+00	541	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
637680219	761	41.29	3	761	4	766	0.0e+00	636	COG4775	Outer membrane protein assembly factor BamA	766
637680220	156	34.39	2	154	13	169	8.0e-17	80	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
637680221	347	49.55	8	340	3	338	7.0e-92	330	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
637680222	144	57.93	1	143	4	145	2.0e-47	181	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
637680223	256	58.82	2	256	6	260	6.0e-106	376	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
637680224	382	47.91	4	382	1	380	4.0e-114	404	COG0763	Lipid A disaccharide synthetase	381
637680225	196	60	10	195	1	190	4.0e-62	230	COG0164	Ribonuclease HII	199
637680226	255	32.2	4	255	1	258	4.0e-44	171	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
637680227	272	47.25	6	272	3	269	4.0e-83	301	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
637680228	918	51.09	7	918	4	910	0.0e+00	1053	COG2352	Phosphoenolpyruvate carboxylase	910
637680229	148	33.11	1	146	4	151	5.0e-14	70.4	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
637680230	150	36	1	149	4	152	6.0e-15	73.5	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
637680231	578	43.95	12	573	1	522	2.0e-130	459	COG1620	L-lactate permease	522
637680232	923	31.07	7	513	1	456	5.0e-65	243	COG0277	FAD/FMN-containing dehydrogenase	459
637680233	480	46.17	13	475	2	458	0.0e+00	531	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
637680234	222	28.38	1	221	1	218	1.0e-27	116	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
637680236	255	39.66	8	241	9	241	3.0e-44	172	COG2186	DNA-binding transcriptional regulator, FadR family	241
637680237	791	49.75	1	790	1	739	0.0e+00	730	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
637680239	319	25.78	7	298	4	346	6.0e-25	108	COG3240	Phospholipase/lecithinase/hemolysin	370
637680240	449	28.07	29	425	13	428	3.0e-46	180	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
637680241	1169	27.46	598	937	2	334	2.0e-39	159	COG0642	Signal transduction histidine kinase	336
637680242	227	22.22	29	198	4	169	3.0e-06	45.7	COG1514	2'-5' RNA ligase	180
637680245	252	40.59	15	252	1	233	5.0e-60	224	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
637680246	659	41.99	1	589	2	562	0.0e+00	492	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
637680247	272	17.83	33	161	13	132	5.0e-09	55.3	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
637680248	641	36.2	8	637	1	646	0.0e+00	464	COG1199	Rad3-related DNA helicase	654
637680251	168	51.55	1	157	2	159	1.0e-45	175	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
637680252	402	44.94	1	400	6	404	6.0e-105	374	COG0303	Molybdopterin biosynthesis enzyme	404
637680253	82	42.86	2	82	1	84	6.0e-15	72.3	COG1977	Molybdopterin converting factor, small subunit	84
637680254	307	36.52	1	279	12	299	3.0e-58	219	COG1161	Ribosome biogenesis GTPase A	322
637680256	279	25.35	4	209	10	218	9.0e-22	97.7	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
637680259	151	22.41	23	138	3	109	3.0e-11	61.5	COG0607	Rhodanese-related sulfurtransferase	110
637680261	184	50.29	1	173	1	172	8.0e-54	203	COG4681	Uncharacterized conserved protein YaeQ, suppresses RfaH defect	181
637680265	629	39.04	6	326	5	330	1.0e-68	254	COG0826	Collagenase-like protease, PrtC family	347
637680268	554	47.42	6	536	1	530	0.0e+00	575	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
637680271	482	30.69	183	482	38	331	2.0e-29	124	COG0642	Signal transduction histidine kinase	336
637680273	469	48.92	11	460	5	462	0.0e+00	471	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
637680279	147	31.2	10	134	5	128	3.0e-25	107	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
637680281	627	41.2	1	461	1	446	7.0e-111	395	COG3276	Selenocysteine-specific translation elongation factor	447
637680283	185	21.47	5	179	4	186	1.0e-10	59.8	COG0655	Multimeric flavodoxin WrbA	207
637680284	444	24.79	46	379	4	337	2.0e-29	123	COG1252	NADH dehydrogenase, FAD-containing subunit	405
637680285	465	53.67	69	463	16	395	4.0e-103	368	COG1921	Seryl-tRNA(Sec) selenium transferase	395
637680286	302	40.53	1	300	6	306	2.0e-73	269	COG3058	Formate dehydrogenase maturation protein FdhE	308
637680287	206	46.12	2	203	1	205	1.0e-46	179	COG2864	Cytochrome b subunit of formate dehydrogenase	218
637680288	295	38.25	19	235	3	202	8.0e-55	207	COG0437	Fe-S-cluster-containing dehydrogenase component	203
637680291	447	44.64	1	447	29	482	4.0e-113	402	COG0513	Superfamily II DNA and RNA helicase	513
637680292	117	37.01	2	117	1	126	2.0e-21	94.2	COG1553	Sulfur relay (sulfurtransferase) complex TusBCD TusD component, DsrE family	126
637680293	582	29.97	88	433	2	335	2.0e-43	170	COG0642	Signal transduction histidine kinase	336
637680294	362	27.9	10	355	84	432	5.0e-65	241	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
637680295	518	38.79	246	516	1	280	5.0e-46	179	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
637680296	275	39.69	1	257	2	258	6.0e-65	240	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
637680297	293	34.68	5	291	1	296	2.0e-53	203	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
637680298	465	46.94	26	465	2	456	0.0e+00	460	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
637680300	160	24.42	3	153	2	163	9.0e-14	69.6	COG4314	Nitrous oxide reductase accessory protein NosL	176
637680302	233	35	13	222	5	219	2.0e-20	93	COG2836	Sulfite exporter TauE/SafE	232
637680303	165	30	1	159	13	172	8.0e-22	96.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
637680304	306	31.79	13	298	12	313	4.0e-43	168	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
637680305	787	34.12	98	787	35	719	4.0e-126	445	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
637680306	188	24.68	8	154	4	154	9.0e-06	43.8	COG4314	Nitrous oxide reductase accessory protein NosL	176
637680307	808	49.65	100	808	5	709	0.0e+00	704	COG2217	Cation transport ATPase	713
637680310	162	26.32	21	162	1	150	2.0e-11	61.8	COG1225	Peroxiredoxin	157
637680312	224	44	1	223	1	222	8.0e-65	240	COG1136	ABC-type lipoprotein export system, ATPase component	226
637680315	185	36.04	1	185	8	204	3.0e-38	151	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
637680318	267	35.43	14	263	1	248	7.0e-53	200	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
637680321	805	41.69	72	798	15	731	0.0e+00	680	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
637680322	880	37.86	1	880	26	915	0.0e+00	722	COG0474	Magnesium-transporting ATPase (P-type)	917
637680326	638	19.14	197	549	48	399	8.0e-20	92.3	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
637680329	344	21.6	5	339	7	296	3.0e-27	116	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
637680330	96	34.07	1	91	1	91	1.0e-15	74.5	COG5470	Uncharacterized conserved protein, DUF1330 family	96
637680333	275	23.85	49	271	53	289	2.0e-20	93.5	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
637680334	316	32.78	1	315	1	342	2.0e-71	262	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
637680335	293	37.98	37	291	6	292	1.0e-46	180	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
637680337	278	31.86	1	220	21	243	1.0e-50	193	COG1718	Serine/threonine-protein kinase RIO1	268
637680338	662	42.92	14	659	3	631	0.0e+00	717	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
637680339	216	23.39	1	214	3	203	8.0e-23	100	COG0778	Nitroreductase	207
637680340	308	52.96	1	294	1	297	6.0e-76	277	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
637680342	397	21.64	29	372	8	358	1.0e-16	81	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
637680344	398	35.94	12	398	6	432	7.0e-101	361	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
637680345	180	21.43	42	147	6	111	1.0e-06	46.4	COG3427	Carbon monoxide dehydrogenase subunit G	146
637680346	1029	44.8	1	1021	1	1021	0.0e+00	1004	COG3696	Cu/Ag efflux pump CusA	1027
637680347	375	27.4	1	357	8	357	1.0e-19	90.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
637680348	413	28.54	7	400	27	435	9.0e-25	108	COG1538	Outer membrane protein TolC	457
637680349	229	45.65	1	222	1	229	4.0e-50	191	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
637680350	467	31.48	162	462	35	336	2.0e-38	153	COG0642	Signal transduction histidine kinase	336
637680351	137	40.58	1	137	2	137	1.0e-38	151	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
637680353	179	42.94	1	175	1	172	1.0e-45	175	COG3040	Bacterial lipocalin	174
637680354	142	21.8	12	142	4	134	6.0e-10	56.8	COG0824	Acyl-CoA thioesterase FadM	137
637680356	402	24.16	39	401	53	436	4.0e-18	86	COG2271	Sugar phosphate permease	448
637680357	273	37.8	142	267	1	127	4.0e-19	88.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
637680358	196	62.7	3	186	1	185	6.0e-76	276	COG2818	3-methyladenine DNA glycosylase Tag	188
637680360	132	55.73	3	132	1	131	7.0e-54	202	COG0229	Peptide methionine sulfoxide reductase MsrB	140
637680361	310	36.22	183	309	1	127	8.0e-22	98	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
637680362	152	52.29	1	152	3	155	4.0e-56	210	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
637680363	732	28.59	50	732	36	727	2.0e-108	387	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
637680364	331	36.45	7	327	2	273	1.0e-50	193	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
637680365	199	33.33	1	187	3	190	2.0e-27	115	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
637680366	231	28.43	26	225	21	215	3.0e-14	72	COG3318	Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C motif	216
637680367	865	35.77	439	711	64	326	9.0e-40	159	COG0642	Signal transduction histidine kinase	336
637680368	671	26.21	30	443	22	395	3.0e-38	153	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
637680371	489	40.17	34	391	8	345	3.0e-65	243	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
637680373	547	30.11	176	547	41	408	5.0e-39	156	COG0840	Methyl-accepting chemotaxis protein	408
637680374	160	42.86	1	160	5	169	4.0e-28	117	COG3613	Nucleoside 2-deoxyribosyltransferase	172
637680375	120	31.58	11	120	8	121	1.0e-19	88.2	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
637680376	155	47.4	1	152	3	155	5.0e-42	163	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
637680377	349	20.74	15	336	1	271	3.0e-19	89.8	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
637680382	300	37.08	197	284	18	106	3.0e-11	63	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
637680383	182	22.67	3	165	1	153	7.0e-10	57.2	COG1225	Peroxiredoxin	157
637680384	304	33.33	1	296	1	296	3.0e-56	212	COG1893	Ketopantoate reductase	307
637680385	268	22.26	8	266	18	293	2.0e-13	69.7	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
637680390	1155	22.22	1	729	1	713	6.0e-38	153	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
637680391	414	29.51	1	400	1	382	1.0e-51	197	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
637680392	524	40.93	8	516	1	530	2.0e-120	426	COG0578	Glycerol-3-phosphate dehydrogenase	532
637680393	502	63.78	3	499	1	497	0.0e+00	767	COG0554	Glycerol kinase	499
637680396	1309	35.17	161	1005	1	743	0.0e+00	684	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
637680396	1309	41.63	1057	1309	2	231	3.0e-71	264	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
637680397	207	25.9	26	182	21	179	4.0e-10	58.3	COG0740	ATP-dependent protease ClpP, protease subunit	200
637680399	186	43.98	13	178	4	168	3.0e-42	164	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
637680400	188	23.33	69	187	4	110	5.0e-08	51.1	COG0607	Rhodanese-related sulfurtransferase	110
637680403	476	34.97	7	472	5	455	1.0e-98	353	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
637680405	1015	36.22	889	1014	2	126	9.0e-21	96.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
637680405	1015	38.8	623	871	93	334	3.0e-45	178	COG0642	Signal transduction histidine kinase	336
637680406	265	60.92	1	261	1	259	8.0e-103	366	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
637680407	548	31.95	5	460	1	396	2.0e-73	270	COG0644	Dehydrogenase (flavoprotein)	396
637680408	136	33.08	9	135	6	133	3.0e-24	104	COG0824	Acyl-CoA thioesterase FadM	137
637680409	448	31.75	2	443	6	410	2.0e-68	253	COG0232	dGTP triphosphohydrolase	412
637680410	201	49.75	1	194	2	198	3.0e-52	198	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
637680412	479	22.83	14	309	19	325	3.0e-06	46.9	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
637680413	1027	39.44	4	1012	2	1059	0.0e+00	1009	COG0587	DNA polymerase III, alpha subunit	1139
637680417	588	24.74	3	379	4	390	5.0e-38	152	COG1680	CubicO group peptidase, beta-lactamase class C family	390
637680418	249	58.38	1	197	3	193	3.0e-69	254	COG1045	Serine acetyltransferase	194
637680419	167	40.85	1	141	1	142	1.0e-36	145	COG1959	DNA-binding transcriptional regulator, IscR family	150
637680420	385	48.97	3	384	1	385	4.0e-121	428	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
637680421	405	61.44	5	389	1	386	0.0e+00	557	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
637680422	127	53.42	1	127	5	147	3.0e-37	147	COG0822	NifU homolog involved in Fe-S cluster formation	150
637680423	107	57.41	1	107	3	110	3.0e-38	149	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
637680424	175	38.95	5	174	1	171	5.0e-19	87.3	COG1076	DnaJ-domain-containing proteins 1	174
637680425	629	46.4	17	606	3	579	0.0e+00	544	COG0443	Molecular chaperone DnaK (HSP70)	579
637680426	114	35.85	1	104	1	102	3.0e-15	73.6	COG0633	Ferredoxin	102
637680427	64	58.06	1	62	1	62	5.0e-20	89.3	COG2975	Fe-S-cluster formation regulator IscX/YfhJ	64
637680428	131	64.35	14	128	10	124	2.0e-41	161	COG3651	Uncharacterized conserved protein, DUF2237 family	125
637680433	279	51.71	73	277	6	210	7.0e-53	200	COG0560	Phosphoserine phosphatase	212
637680435	341	56.46	1	333	16	347	0.0e+00	497	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
637680436	1147	48.6	15	1146	7	1134	0.0e+00	1346	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
637680438	549	26.09	42	524	7	431	2.0e-52	200	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
637680440	370	37.69	53	311	5	260	7.0e-66	244	COG1180	Pyruvate-formate lyase-activating enzyme	260
637680441	180	33.7	3	179	8	190	9.0e-31	126	COG2078	Uncharacterized conserved protein, AMMECR1 domain	203
637680442	267	32.49	5	260	4	278	7.0e-45	174	COG1355	Predicted class III extradiol dioxygenase, MEMO1 family	279
637680443	418	32.97	39	407	1	360	3.0e-34	140	COG3174	Uncharacterized membrane protein, DUF4010 family	371
637680444	228	48.26	1	225	2	227	2.0e-62	232	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
637680445	160	62.03	3	160	1	158	3.0e-62	230	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
637680446	193	33.33	17	190	2	176	3.0e-25	108	COG1514	2'-5' RNA ligase	180
637680449	280	33.47	1	240	8	246	2.0e-33	135	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
637680450	433	29.05	122	433	9	331	4.0e-32	132	COG0642	Signal transduction histidine kinase	336
637680451	243	44.21	8	239	1	229	1.0e-62	233	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
637680452	229	38.22	1	218	1	218	3.0e-36	145	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
637680453	153	32.69	1	137	5	160	1.0e-16	79.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
637680454	260	41.97	72	252	9	201	2.0e-38	152	COG1573	Uracil-DNA glycosylase	202
637680456	300	32.44	4	299	4	295	1.0e-39	157	COG0583	DNA-binding transcriptional regulator, LysR family	297
637680457	370	46.69	5	360	3	357	1.0e-99	356	COG0787	Alanine racemase	360
637680458	453	61.27	1	451	1	455	0.0e+00	642	COG1066	Predicted ATP-dependent serine protease	456
637680460	827	37.06	3	826	6	829	0.0e+00	563	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
637680461	132	23.31	1	128	1	133	8.0e-10	56.1	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
637680463	195	25.73	25	195	18	188	6.0e-18	84.1	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
637680464	708	28.11	334	701	10	364	9.0e-43	169	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
637680465	320	22.01	57	310	25	268	1.0e-18	87.1	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
637680466	115	23	1	99	3	100	9.0e-12	62.3	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
637680468	129	36.43	1	129	3	128	5.0e-28	116	COG2346	Truncated hemoglobin YjbI	133
637680469	613	64.74	5	611	4	601	0.0e+00	957	COG1217	Predicted membrane GTPase involved in stress response	603
637680470	357	43.56	34	357	2	322	5.0e-100	358	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
637680474	402	58.88	6	399	2	395	0.0e+00	565	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
637680475	690	66.32	14	680	1	663	0.0e+00	1082	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
637680476	160	40.26	1	154	1	139	1.0e-33	136	COG0394	Protein-tyrosine-phosphatase	139
637680477	870	51.83	1	490	1	487	0.0e+00	517	COG1530	Ribonuclease G or E	487
637680478	334	40.54	13	305	5	289	2.0e-70	259	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
637680479	119	32.17	1	115	1	106	1.0e-14	71.5	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
637680480	320	30	13	314	2	301	2.0e-56	213	COG0616	Periplasmic serine protease, ClpP class	317
637680481	235	32.77	1	235	3	225	2.0e-47	182	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
637680482	193	40.72	1	193	1	192	5.0e-50	190	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
637680483	187	26.59	26	185	6	176	1.0e-15	76.5	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
637680484	59	41.07	1	55	1	56	4.0e-11	59.9	COG0333	Ribosomal protein L32	57
637680485	339	51.79	4	335	3	338	2.0e-120	425	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
637680486	319	58.7	1	319	2	322	6.0e-117	413	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
637680487	308	52.13	1	303	2	306	7.0e-92	330	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
637680488	248	45.24	3	245	2	250	2.0e-47	182	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
637680489	78	62.82	1	78	3	80	4.0e-12	63	COG0236	Acyl carrier protein	80
637680490	411	58.11	3	411	2	411	0.0e+00	499	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
637680492	525	55.66	5	524	9	514	0.0e+00	660	COG0029	Aspartate oxidase	518
637680493	199	38.5	7	193	2	181	7.0e-33	133	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
637680494	147	26.67	13	145	6	140	3.0e-11	61.1	COG3086	Positive regulator of sigma E activity	150
637680495	473	42.82	26	363	33	347	3.0e-72	266	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
637680497	596	71.36	1	596	6	602	0.0e+00	1047	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
637680498	262	30.97	40	145	9	163	3.0e-13	69.2	COG0681	Signal peptidase I	166
637680500	222	52.75	8	220	13	229	2.0e-65	242	COG0571	dsRNA-specific ribonuclease	235
637680501	294	50.84	1	294	1	296	3.0e-101	361	COG1159	GTPase Era, involved in 16S rRNA processing	298
637680502	242	33.2	4	242	2	246	1.0e-36	146	COG1381	Recombinational DNA repair protein (RecF pathway)	251
637680503	251	57.32	2	247	1	242	4.0e-77	281	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
637680504	125	44.8	1	124	1	125	1.0e-32	131	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
637680505	339	38.57	2	339	1	343	4.0e-66	245	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
637680506	185	44.96	1	128	3	131	7.0e-33	133	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
637680507	360	45.5	5	357	4	366	4.0e-100	358	COG4394	Uncharacterized protein	370
637680508	215	29.84	31	215	29	200	8.0e-24	103	COG1573	Uracil-DNA glycosylase	202
637680509	603	50.41	1	602	1	581	0.0e+00	636	COG0322	Excinuclease UvrABC, nuclease subunit	581
637680510	192	43.16	1	189	10	192	2.0e-23	102	COG0558	Phosphatidylglycerophosphate synthase	192
637680515	152	40.79	1	152	1	142	1.0e-34	138	COG5319	Uncharacterized protein	142
637680516	341	30.46	6	328	3	303	2.0e-36	146	COG3547	Transposase	303
637680518	439	23.7	10	213	3	213	2.0e-19	90.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
637680520	868	39.7	229	491	4	266	7.0e-71	262	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
637680521	2932	41.08	1837	2922	2	1051	0.0e+00	918	COG3459	Cellobiose phosphorylase	1056
637680524	95	60.92	6	92	5	91	1.0e-22	97.8	COG3461	Uncharacterized protein	103
637680531	187	28.49	14	182	3	181	9.0e-19	87	COG2930	Lipid-binding SYLF domain	227
637680533	343	27.46	67	342	43	312	4.0e-28	118	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
637680536	366	22.04	22	332	7	234	6.0e-25	108	COG0176	Transaldolase	239
637680537	788	70.26	7	784	14	792	0.0e+00	1201	COG3957	Phosphoketolase	793
637680539	315	33.79	1	302	1	349	6.0e-61	227	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
637680541	141	37.86	4	140	9	143	8.0e-22	96.2	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
637680542	542	29.14	33	507	4	460	3.0e-75	276	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
637680543	479	56.33	1	473	1	471	0.0e+00	675	COG0362	6-phosphogluconate dehydrogenase	473
637680544	487	48.55	6	474	6	481	0.0e+00	577	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
637680545	232	33.61	4	227	1	238	5.0e-42	164	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
637680546	449	26.81	1	445	2	422	4.0e-35	142	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
637680547	192	38.07	4	177	1	169	9.0e-31	126	COG0431	NAD(P)H-dependent FMN reductase	184
637680549	135	27.03	2	111	10	120	4.0e-17	80.5	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
637680552	852	35.03	26	843	42	917	0.0e+00	607	COG0474	Magnesium-transporting ATPase (P-type)	917
637680555	475	36.84	92	475	49	438	2.0e-64	240	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
637680562	235	43.81	10	232	1	226	2.0e-29	122	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
637680563	343	35.32	92	340	75	313	2.0e-53	203	COG2829	Outer membrane phospholipase A	317
637680564	211	43.2	1	202	4	205	6.0e-50	190	COG0288	Carbonic anhydrase	207
637680566	237	43.62	1	237	2	244	1.0e-48	186	COG3279	DNA-binding response regulator, LytR/AlgR family	244
637680567	577	57.48	6	558	2	550	0.0e+00	668	COG3275	Sensor histidine kinase, LytS/YehU family	557
637680568	604	37.12	4	596	3	568	0.0e+00	492	COG1966	Carbon starvation protein CstA	575
637680569	751	60.48	11	750	8	755	0.0e+00	964	COG1882	Pyruvate-formate lyase	755
637680570	264	37.76	25	262	17	254	1.0e-56	213	COG1180	Pyruvate-formate lyase-activating enzyme	260
637680571	493	29.07	204	482	16	325	3.0e-48	186	COG0280	Phosphotransacetylase	327
637680571	493	31.21	19	168	2	158	4.0e-18	86.7	COG2030	Acyl dehydratase	159
637680572	403	45.11	9	399	4	396	6.0e-122	431	COG0282	Acetate kinase	396
637680573	316	41.61	35	307	6	261	2.0e-50	193	COG2116	Formate/nitrite transporter FocA, FNT family	265
637680576	214	30.05	5	205	39	244	1.0e-25	109	COG1360	Flagellar motor protein MotB	244
637680578	680	40.96	142	388	89	326	6.0e-42	166	COG0642	Signal transduction histidine kinase	336
637680580	548	29	6	522	10	531	1.0e-74	274	COG2831	Hemolysin activation/secretion protein	554
637680581	493	35.15	19	180	1	161	4.0e-26	112	COG3666	Transposase	161
637680582	183	25.88	19	180	20	188	6.0e-16	77.2	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
637680583	163	28.8	17	141	1	125	9.0e-10	56.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
637680584	405	20.3	1	385	4	394	8.0e-12	65.2	COG0475	Kef-type K+ transport system, membrane component KefB	397
637680585	260	37.18	2	233	1	219	7.0e-47	180	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
637680586	424	21.87	28	353	2	344	5.0e-13	69.2	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
637680587	384	37.81	14	376	2	366	2.0e-86	313	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
637680588	420	19.79	53	392	1	367	3.0e-12	66.9	COG1680	CubicO group peptidase, beta-lactamase class C family	390
637680589	259	27.03	1	257	2	253	5.0e-10	58.5	COG0730	Uncharacterized membrane protein YfcA	258
637680590	472	45.26	1	469	1	475	0.0e+00	563	COG0469	Pyruvate kinase	477
637680591	426	59.19	5	422	4	422	0.0e+00	518	COG2379	Glycerate-2-kinase	422
637680592	443	21.38	18	434	17	432	2.0e-26	114	COG2271	Sugar phosphate permease	448
637680593	180	42.77	5	177	10	181	2.0e-38	152	COG3803	Uncharacterized conserved protein, DUF924 family	182
637680595	387	36.66	12	373	1	347	1.0e-71	263	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
637680596	226	34.62	17	198	4	182	1.0e-25	109	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
637680598	140	38.14	15	127	15	131	1.0e-27	115	COG3474	Cytochrome c2	135
637680599	543	27.62	116	281	1	181	9.0e-14	72.1	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
637680599	543	46	293	541	2	251	2.0e-67	250	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
637680600	231	28.85	20	227	8	207	2.0e-26	112	COG0400	Predicted esterase	207
637680601	311	29.01	1	291	1	287	2.0e-36	146	COG0583	DNA-binding transcriptional regulator, LysR family	297
637680603	204	46.58	29	189	1	156	2.0e-49	188	COG0242	Peptide deformylase	168
637680604	170	47.13	1	167	2	175	2.0e-46	178	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
637680605	331	75.56	17	330	32	346	0.0e+00	523	COG1613	ABC-type sulfate transport system, periplasmic component	348
637680606	97	33.33	6	97	8	100	6.0e-10	56	COG0640	DNA-binding transcriptional regulator, ArsR family	110
637680609	324	58.31	5	309	2	299	2.0e-102	365	COG0031	Cysteine synthase	300
637680610	176	29.84	52	175	6	108	1.0e-11	62.6	COG0607	Rhodanese-related sulfurtransferase	110
637680614	93	37.8	1	82	1	82	4.0e-17	79.6	COG4378	Uncharacterized protein	103
637680615	371	64.15	1	371	1	371	0.0e+00	524	COG0686	Alanine dehydrogenase	371
637680616	712	33.11	154	589	16	401	9.0e-73	268	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
637680617	350	22.67	46	334	2	279	2.0e-20	93.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
637680618	442	49.78	1	442	2	462	0.0e+00	502	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
637680619	120	35.04	1	115	1	117	3.0e-17	80.7	COG3232	5-carboxymethyl-2-hydroxymuconate isomerase	127
637680620	591	46.39	2	583	10	603	0.0e+00	506	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
637680621	263	51.98	1	252	1	248	3.0e-90	325	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
637680622	271	41.95	2	268	6	256	1.0e-53	203	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
637680623	326	25.74	1	326	3	335	2.0e-31	129	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
637680624	411	32.18	74	411	17	364	4.0e-55	209	COG4269	Uncharacterized membrane protein YjgN, DUF898 family	364
637680625	327	26.3	83	327	15	298	1.0e-16	81.1	COG0501	Zn-dependent protease with chaperone function	302
637680627	142	21.95	16	137	11	131	1.0e-08	52.6	COG3439	Uncharacterized conserved protein, DUF302 family	137
637680628	385	49.74	6	382	3	383	7.0e-128	450	COG1979	Alcohol dehydrogenase YqhD, Fe-dependent ADH family	384
637680629	205	22.55	1	204	2	201	5.0e-10	58.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
637680630	391	30.91	6	357	2	365	8.0e-34	138	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
637680631	1040	47.82	1	1023	2	1008	0.0e+00	992	COG0841	Multidrug efflux pump subunit AcrB	1009
637680632	475	39.57	15	472	1	449	1.0e-65	244	COG1538	Outer membrane protein TolC	457
637680638	933	29.6	656	905	1	220	2.0e-31	131	COG4253	Uncharacterized conserved protein, DUF2345 family	278
637680638	933	30.13	13	643	3	549	8.0e-103	368	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
637680640	899	40.97	11	899	1	784	0.0e+00	780	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
637680641	354	36.31	1	346	1	327	8.0e-64	237	COG3520	Predicted component of the type VI protein secretion system	335
637680642	610	38	1	609	2	620	0.0e+00	489	COG3519	Type VI protein secretion system component VasA	621
637680643	159	43.51	1	152	3	155	4.0e-26	110	COG3518	Predicted component of the type VI protein secretion system	157
637680644	178	28.81	1	173	2	159	2.0e-26	111	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
637680645	494	55.89	1	492	4	494	0.0e+00	706	COG3517	Predicted component of the type VI protein secretion system	495
637680646	170	46.39	5	170	2	167	9.0e-47	179	COG3516	Predicted component of the type VI protein secretion system	169
637680648	189	26.15	18	147	7	134	5.0e-13	67.6	COG3521	Predicted component of the type VI protein secretion system	159
637680649	447	32	1	446	2	445	6.0e-90	324	COG3522	Predicted component of the type VI protein secretion system	446
637680650	257	26.34	3	242	21	258	6.0e-37	147	COG3455	Type VI protein secretion system component VasF	262
637680651	911	33.28	9	586	5	535	3.0e-105	376	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
637680651	911	35.37	610	903	1	273	2.0e-44	174	COG4253	Uncharacterized conserved protein, DUF2345 family	278
637680654	365	24.93	4	359	4	346	3.0e-32	132	COG3515	Predicted component of the type VI protein secretion system	346
637680655	261	32.52	96	258	26	187	1.0e-24	106	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
637680656	327	28.5	12	225	11	216	3.0e-18	86.3	COG3913	Uncharacterized protein	227
637680657	1270	29.4	7	1216	7	1171	0.0e+00	724	COG3523	Type VI protein secretion system component VasK	1188
637680659	88	47.62	1	84	10	92	6.0e-16	75.8	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
637680663	257	54.12	1	252	2	255	5.0e-87	314	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
637680664	120	50.43	4	120	2	117	4.0e-36	143	COG3215	Tfp pilus assembly protein PilZ	117
637680665	339	31.19	17	339	19	319	2.0e-33	136	COG0470	DNA polymerase III, delta prime subunit	324
637680666	204	50.5	1	200	1	202	5.0e-60	223	COG0125	Thymidylate kinase	208
637680667	331	40.95	1	331	5	341	5.0e-98	351	COG1559	Cell division protein YceG, involved in septum cleavage	342
637680668	339	30.04	32	313	6	273	1.0e-52	200	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
637680669	249	48.22	1	238	1	253	2.0e-61	229	COG3332	Uncharacterized conserved protein, contains NRDE domain	270
637680671	146	61.15	1	138	12	150	9.0e-45	172	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
637680677	267	32.55	7	248	3	254	1.0e-42	166	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
637680680	650	20.49	1	590	20	595	4.0e-28	120	COG4928	Predicted P-loop ATPase, KAP-like	646
637680688	667	23.29	42	250	27	236	8.0e-07	49.5	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
637680689	226	36.67	14	190	2	180	4.0e-32	131	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
637680690	1669	30.3	393	908	1	545	3.0e-64	241	COG4646	Adenine-specific DNA methylase, N12 class	637
637680693	224	28.7	1	218	1	204	5.0e-21	94.7	COG2135	Putative SOS response-associated peptidase YedK	226
637680707	436	21.93	2	413	1	389	4.0e-17	82.9	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
637680713	91	38.1	25	87	2	64	5.0e-10	56.1	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
637680714	119	37.5	18	81	5	68	4.0e-07	46.7	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
637680715	203	51.31	13	202	1	190	2.0e-42	165	COG2119	Putative Ca2+/H+ antiporter, TMEM165/GDT1 family	190
637680716	350	23.32	11	289	8	290	2.0e-11	64.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
637680717	429	27.27	13	288	40	310	1.0e-18	88.3	COG3344	Retron-type reverse transcriptase	328
637680718	111	22.52	1	110	1	102	3.0e-06	43.6	COG0347	Nitrogen regulatory protein PII	112
637680719	1032	45.82	1	1026	1	1026	0.0e+00	1068	COG3696	Cu/Ag efflux pump CusA	1027
637680720	398	32.34	60	389	32	363	1.0e-26	114	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
637680721	436	25.62	31	422	39	443	2.0e-26	114	COG1538	Outer membrane protein TolC	457
637680723	144	33.33	2	114	1	111	7.0e-18	83.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
637680724	743	42.19	51	742	4	709	0.0e+00	656	COG2217	Cation transport ATPase	713
637680725	463	34.02	130	462	1	328	3.0e-40	159	COG0642	Signal transduction histidine kinase	336
637680726	225	46.96	1	225	1	229	2.0e-58	218	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
637680728	149	49.64	9	147	7	144	1.0e-41	162	COG3019	Uncharacterized conserved protein	149
637680729	112	37.11	5	100	7	95	5.0e-09	53.1	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
637680730	424	24.29	11	421	22	443	6.0e-24	105	COG1538	Outer membrane protein TolC	457
637680731	546	31.8	104	412	32	354	3.0e-25	110	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
637680731	546	33.33	441	522	22	104	7.0e-10	59.3	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
637680732	1051	50.43	1	1040	1	1025	0.0e+00	1198	COG3696	Cu/Ag efflux pump CusA	1027
637680734	772	45.65	23	67	5	50	8.0e-10	59.6	COG3350	Uncharacterized conserved protein, YHS domain	53
637680734	772	46.11	79	771	45	709	0.0e+00	695	COG2217	Cation transport ATPase	713
637680739	153	37.9	23	146	6	127	2.0e-26	111	COG1815	Flagellar basal body rod protein FlgB	133
637680742	167	44.19	10	52	5	47	6.0e-09	53.8	COG3350	Uncharacterized conserved protein, YHS domain	53
637680744	216	21.54	16	209	2	185	5.0e-14	71.2	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
637680748	116	38.3	22	114	8	101	3.0e-09	53.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
637680752	275	30.35	66	265	36	224	2.0e-15	76.6	COG2801	Transposase InsO and inactivated derivatives	232
637680758	336	25.71	17	322	12	296	1.0e-23	103	COG4643	Uncharacterized domain associated with phage/plasmid primase	366
637680760	269	40.8	91	261	4	177	4.0e-33	135	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
637680762	144	50	4	143	1	140	7.0e-33	133	COG2510	Uncharacterized membrane protein	140
637680763	471	27.3	119	452	3	332	4.0e-38	153	COG0642	Signal transduction histidine kinase	336
637680764	221	42.61	1	220	1	228	1.0e-50	192	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
637680765	252	47.15	4	249	7	252	8.0e-57	213	COG4705	Uncharacterized membrane-anchored protein	258
637680767	260	50.81	1	247	1	247	2.0e-67	249	COG4705	Uncharacterized membrane-anchored protein	258
637680778	225	29.11	62	217	31	187	3.0e-15	75.6	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
637680784	272	20.38	5	263	2	243	2.0e-10	59.5	COG1651	Protein-disulfide isomerase	244
637680786	855	18.39	36	801	18	751	9.0e-32	132	COG3451	Type IV secretory pathway, VirB4 component	796
637680788	198	25.52	61	198	28	169	3.0e-11	62.3	COG4959	Type IV secretory pathway, protease TraF	173
637680803	544	44.76	3	205	1	197	2.0e-54	207	COG0518	GMP synthase - Glutamine amidotransferase domain	198
637680803	544	65.38	207	544	1	315	0.0e+00	526	COG0519	GMP synthase, PP-ATPase domain/subunit	315
637680804	487	30.32	256	476	1	170	6.0e-33	135	COG0516	IMP dehydrogenase/GMP reductase	170
637680806	108	55.67	3	99	2	98	2.0e-26	110	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
637680807	147	43.15	1	145	1	146	5.0e-37	146	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
637680808	149	60.4	1	149	6	153	4.0e-52	197	COG0691	tmRNA-binding protein	153
637680809	211	36.54	5	210	2	209	1.0e-48	186	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
637680812	537	38.6	3	535	2	544	1.0e-119	423	COG1165	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase	566
637680813	283	57.36	9	137	6	134	2.0e-48	186	COG2904	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, N-terminal domain	137
637680814	860	47.44	7	856	1	842	0.0e+00	925	COG0249	DNA mismatch repair ATPase MutS	843
637680816	166	42.17	3	163	1	161	1.0e-33	135	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
637680817	705	35.42	7	245	12	248	2.0e-34	141	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
637680817	705	41.98	302	592	1	292	6.0e-82	299	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
637680818	517	38.05	7	515	3	525	6.0e-117	414	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
637680819	395	36.32	4	394	1	392	3.0e-66	245	COG0183	Acetyl-CoA acetyltransferase	392
637680820	378	48.45	1	377	1	388	2.0e-92	332	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
637680821	266	42.42	1	263	2	257	1.0e-46	179	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
637680822	610	35.3	1	605	9	610	0.0e+00	492	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
637680823	269	53.53	6	246	3	237	5.0e-81	294	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
637680824	389	25.6	21	351	1	331	2.0e-35	144	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637680825	348	37.62	21	337	5	313	1.0e-43	170	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
637680826	292	35.02	1	291	1	297	6.0e-37	147	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
637680827	278	50.79	6	259	1	250	2.0e-86	312	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
637680828	335	34.65	236	335	23	123	2.0e-15	76.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
637680829	156	50	1	156	2	157	3.0e-47	181	COG1225	Peroxiredoxin	157
637680830	94	47.19	1	89	24	112	2.0e-16	77.3	COG2919	Cell division protein FtsB	117
637680831	427	69.48	1	426	1	423	0.0e+00	666	COG0148	Enolase	423
637680832	278	61.68	1	274	5	276	7.0e-120	423	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
637680833	546	64.22	2	544	1	533	0.0e+00	872	COG0504	CTP synthase (UTP-ammonia lyase)	533
637680835	383	25.21	6	360	3	305	7.0e-37	148	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
637680838	303	32	1	299	4	293	1.0e-63	236	COG1131	ABC-type multidrug transport system, ATPase component	293
637680839	410	27.83	195	404	79	281	1.0e-11	64.9	COG0842	ABC-type multidrug transport system, permease component	286
637680841	359	28.47	1	358	1	410	7.0e-40	158	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
637680843	286	42.56	2	286	22	304	8.0e-54	203	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
637680844	300	33.45	1	279	5	296	7.0e-61	227	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
637680845	901	33.87	774	896	2	123	1.0e-20	95.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
637680845	901	36.13	487	759	70	335	5.0e-41	163	COG0642	Signal transduction histidine kinase	336
637680846	506	33.5	3	199	1	202	4.0e-37	149	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
637680846	506	41.84	218	490	10	283	3.0e-55	209	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
637680847	287	51.25	9	286	2	278	7.0e-85	307	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
637680849	475	32.01	1	473	1	410	3.0e-91	329	COG0498	Threonine synthase	411
637680852	358	33.02	13	217	15	226	2.0e-22	100	COG0705	Membrane associated serine protease, rhomboid family	228
637680853	436	50.15	1	320	1	329	5.0e-100	358	COG0460	Homoserine dehydrogenase	333
637680854	414	36.63	9	403	2	393	1.0e-96	346	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
637680855	138	40.65	16	136	5	126	7.0e-27	113	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
637680856	479	51.91	4	342	2	333	6.0e-125	441	COG0836	Mannose-1-phosphate guanylyltransferase	333
637680856	479	54.33	351	477	1	127	5.0e-37	149	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
637680858	253	49.77	3	222	1	220	4.0e-74	271	COG1136	ABC-type lipoprotein export system, ATPase component	226
637680861	406	23.44	5	404	3	407	3.0e-41	163	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
637680862	404	24.58	1	400	1	406	4.0e-44	172	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
637680864	207	30.05	18	205	20	206	1.0e-21	96.3	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
637680865	480	19.09	1	417	46	456	2.0e-26	114	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
637680866	323	35.35	108	320	40	249	4.0e-27	115	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
637680868	358	31.18	1	262	9	269	4.0e-36	145	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
637680869	390	37.84	12	372	6	365	5.0e-88	318	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
637680872	406	19.44	3	387	1	366	8.0e-19	88.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
637680874	387	27.18	8	381	4	381	3.0e-34	139	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
637680875	635	29.94	1	632	1	541	4.0e-106	379	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
637680876	406	29.63	2	403	1	381	8.0e-35	141	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
637680877	368	25.79	7	360	2	381	3.0e-36	145	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
637680878	451	25.93	33	450	14	438	9.0e-51	194	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
637680880	672	20.69	359	610	2	291	5.0e-23	103	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
637680881	492	21.92	1	438	5	450	1.0e-13	72.1	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
637680883	391	24.09	1	363	1	379	1.0e-23	104	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
637680885	388	22.45	47	379	40	367	1.0e-19	91.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
637680886	342	19.25	2	316	17	308	1.0e-12	67.6	COG3594	Fucose 4-O-acetylase or related acetyltransferase	343
637680888	527	37.81	19	415	4	395	2.0e-73	270	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
637680892	276	22.78	39	267	11	232	1.0e-15	77.3	COG2801	Transposase InsO and inactivated derivatives	232
637680893	358	20.17	8	357	17	365	6.0e-14	72.1	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
637680894	555	20.7	35	543	105	535	1.0e-39	158	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
637680900	553	32.47	22	549	7	527	1.0e-93	337	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
637680901	412	35.47	12	412	1	394	2.0e-79	290	COG0019	Diaminopimelate decarboxylase	394
637680902	460	47.64	270	460	40	226	6.0e-60	225	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
637680904	451	45.95	8	450	6	456	7.0e-126	444	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
637680906	426	37.53	1	421	9	433	4.0e-113	401	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
637680907	300	24.91	13	271	13	278	5.0e-17	82.1	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
637680915	141	50.42	22	140	1	119	6.0e-28	116	COG1734	RNA polymerase-binding transcription factor DksA	120
637680916	715	64.36	1	693	1	690	0.0e+00	1014	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
637680917	89	64.04	1	89	1	89	3.0e-28	116	COG0184	Ribosomal protein S15P/S13E	89
637680918	299	42.23	4	297	8	271	6.0e-67	247	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
637680919	123	43.64	8	115	6	115	3.0e-26	110	COG0858	Ribosome-binding factor A	118
637680920	904	62.92	402	904	1	507	0.0e+00	673	COG0532	Translation initiation factor IF-2, a GTPase	509
637680921	490	52.55	158	352	1	190	1.0e-48	188	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
637680922	146	40.94	1	145	8	153	5.0e-30	123	COG0779	Ribosome maturation factor RimP	153
637680923	340	46.43	84	328	1	247	6.0e-69	254	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
637680924	178	47.19	1	177	4	179	3.0e-43	167	COG1386	Chromosome segregation and condensation protein ScpB	184
637680925	283	43.37	39	281	1	248	3.0e-45	175	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
637680926	96	54.44	7	96	22	111	3.0e-21	93.1	COG3952	Uncharacterized N-terminal domain of lipid-A-disaccharide synthase	113
637680928	217	31.94	6	216	13	221	8.0e-13	67.3	COG1994	Zn-dependent protease (includes SpoIVFB)	230
637680929	208	40.58	2	207	1	206	4.0e-56	211	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
637680930	295	41.57	21	274	3	253	7.0e-50	191	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
637680931	363	49.6	1	361	4	375	1.0e-107	383	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
637680932	128	55.2	1	123	2	126	2.0e-37	148	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
637680933	963	55.51	10	442	1	445	0.0e+00	596	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
637680933	963	61.05	470	934	28	496	0.0e+00	710	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
637680935	335	33.24	1	307	2	344	2.0e-67	249	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
637680936	306	31.58	1	301	7	298	7.0e-45	174	COG0010	Arginase family enzyme	305
637680937	213	48.78	7	207	4	208	2.0e-47	182	COG3132	Uncharacterized conserved protein YceH, UPF0502 family	215
637680940	86	41.77	1	79	1	79	3.0e-21	93.4	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
637680941	455	35.9	142	447	21	327	5.0e-39	155	COG0642	Signal transduction histidine kinase	336
637680942	223	44.49	1	221	1	226	2.0e-56	212	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
637680944	306	44.75	1	293	1	293	4.0e-79	288	COG3781	Predicted membrane chloride channel, bestrophin family	306
637680945	105	32.32	3	98	5	103	2.0e-12	63.9	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
637680946	416	22.59	3	413	20	443	5.0e-20	92.5	COG1538	Outer membrane protein TolC	457
637680947	504	28.74	84	399	23	352	8.0e-22	99	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
637680947	504	30.85	410	502	18	107	4.0e-08	53.1	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
637680948	1044	51	1	1041	1	1024	0.0e+00	1186	COG3696	Cu/Ag efflux pump CusA	1027
637680952	274	51.98	8	256	4	254	8.0e-89	320	COG0024	Methionine aminopeptidase	255
637680955	331	36.48	9	295	17	318	6.0e-54	204	COG0226	ABC-type phosphate transport system, periplasmic component	318
637680957	600	20.26	7	293	9	299	2.0e-17	84.6	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
637680958	211	50	4	205	1	200	2.0e-57	215	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
637680959	698	22.16	139	304	4	150	8.0e-09	56.1	COG2010	Cytochrome c, mono- and diheme variants	150
637680959	698	49.43	442	698	15	275	1.0e-79	291	COG3258	Cytochrome c	293
637680960	174	31.36	35	152	5	110	4.0e-12	64.9	COG1416	Intracellular sulfur oxidation protein, DsrE/DsrF family	112
637680962	292	29.01	3	291	1	290	5.0e-33	135	COG0583	DNA-binding transcriptional regulator, LysR family	297
637680963	336	47.63	1	335	4	334	5.0e-60	225	COG2855	Uncharacterized membrane protein YadS	334
637680965	422	24.66	114	392	1	274	8.0e-12	65.3	COG4973	Site-specific recombinase XerC	299
637680982	406	43.27	1	405	1	447	2.0e-120	426	COG0527	Aspartokinase	447
637680983	321	42.31	17	321	4	312	1.0e-80	293	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
637680984	315	46.18	2	291	1	301	7.0e-64	237	COG0714	MoxR-like ATPase	329
637680985	316	21.85	34	316	4	302	2.0e-18	86.8	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
637680987	347	34.74	1	330	10	339	7.0e-72	264	COG2951	Membrane-bound lytic murein transglycosylase B	343
637680988	309	43.75	40	308	70	341	7.0e-65	241	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
637680989	304	30.8	45	304	1	267	3.0e-33	136	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
637680990	216	50	11	216	1	206	3.0e-55	208	COG2518	Protein-L-isoaspartate O-methyltransferase	209
637680991	246	53.97	1	246	1	252	4.0e-87	314	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
637680993	481	20.68	191	408	79	296	1.0e-06	48.3	COG4974	Site-specific recombinase XerD	300
637681001	137	27.54	1	134	3	132	8.0e-16	76	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
637681013	1669	30	393	908	1	545	4.0e-68	254	COG4646	Adenine-specific DNA methylase, N12 class	637
637681026	645	19.81	1	515	1	496	3.0e-27	117	COG3593	Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains	581
637681027	553	22.75	134	549	187	649	3.0e-39	157	COG0210	Superfamily I DNA or RNA helicase	655
637681028	445	20.62	2	408	1	390	2.0e-15	77.1	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
637681030	126	53.33	1	90	2	90	6.0e-25	105	COG0776	Bacterial nucleoid DNA-binding protein	94
637681033	91	32.81	24	87	1	64	9.0e-09	51.9	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
637681040	336	23.49	17	322	12	296	3.0e-18	86.6	COG4643	Uncharacterized domain associated with phage/plasmid primase	366
637681042	323	40.18	1	323	1	322	8.0e-82	297	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
637681044	191	57.92	1	183	1	182	5.0e-64	237	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
637681045	282	20.45	62	281	19	230	1.0e-15	77.3	COG3253	Chlorite dismutase	230
637681046	237	22.47	62	237	37	202	4.0e-07	48.8	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
637681048	333	33.25	9	288	4	384	3.0e-68	252	COG1140	Nitrate reductase beta subunit	513
637681050	468	42.46	5	465	2	462	1.0e-121	430	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
637681051	623	30.37	274	615	2	336	4.0e-37	149	COG0642	Signal transduction histidine kinase	336
637681052	671	27.78	433	666	1	230	1.0e-08	55.4	COG2202	PAS domain	232
637681054	213	38.5	1	213	1	213	4.0e-33	134	COG4944	Uncharacterized protein	213
637681055	190	30.17	17	190	2	179	6.0e-18	84	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
637681056	198	40.61	7	198	21	216	2.0e-37	148	COG4117	Thiosulfate reductase cytochrome b subunit	221
637681057	262	32.1	30	261	1	243	3.0e-50	192	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
637681064	448	42.67	10	448	6	461	1.0e-126	447	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
637681065	484	26.32	188	479	43	328	1.0e-27	117	COG0642	Signal transduction histidine kinase	336
637681066	292	30.03	13	290	4	295	1.0e-36	147	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
637681067	231	42.41	13	198	8	191	3.0e-47	181	COG0437	Fe-S-cluster-containing dehydrogenase component	203
637681068	285	24.91	7	279	9	301	1.0e-15	77.6	COG3301	Formate-dependent nitrite reductase, membrane component NrfD	305
637681069	879	28.6	5	823	1	765	2.0e-108	387	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
637681070	280	22.51	32	213	9	185	1.0e-07	50.4	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
637681076	327	46.77	5	327	1	322	3.0e-96	345	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
637681078	318	20.06	1	315	5	332	3.0e-23	102	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
637681081	1039	39.24	1	1026	1	1022	0.0e+00	893	COG3696	Cu/Ag efflux pump CusA	1027
637681084	432	21.72	24	428	27	445	6.0e-14	72.5	COG1538	Outer membrane protein TolC	457
637681086	145	42.47	1	144	1	146	2.0e-36	145	COG3019	Uncharacterized conserved protein	149
637681089	112	23.42	1	111	1	102	3.0e-08	50.2	COG0347	Nitrogen regulatory protein PII	112
637681090	1032	46.48	1	1022	1	1022	0.0e+00	1059	COG3696	Cu/Ag efflux pump CusA	1027
637681091	399	32.63	61	390	32	363	3.0e-26	113	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
637681092	432	25.37	31	422	39	443	1.0e-25	111	COG1538	Outer membrane protein TolC	457
637681094	166	37.65	1	166	1	166	3.0e-30	124	COG0597	Lipoprotein signal peptidase	167
637681095	739	41.77	47	739	6	710	0.0e+00	639	COG2217	Cation transport ATPase	713
637681096	112	51.38	4	111	1	109	1.0e-23	101	COG1742	Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily	109
637681097	162	34.45	1	118	1	119	2.0e-20	92.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
637681098	185	32.7	6	156	17	175	3.0e-24	105	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
637681099	136	24.27	31	130	32	133	2.0e-09	55	COG1765	Uncharacterized OsmC-related protein	137
637681100	350	52.87	3	350	4	342	9.0e-95	340	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
637681101	590	32.52	8	315	2	318	1.0e-47	184	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
637681103	129	26.15	1	122	18	139	3.0e-12	64.1	COG0394	Protein-tyrosine-phosphatase	139
637681104	168	34.97	5	142	2	136	3.0e-27	114	COG0394	Protein-tyrosine-phosphatase	139
637681105	112	37.23	1	94	10	100	9.0e-10	55.6	COG0640	DNA-binding transcriptional regulator, ArsR family	110
637681109	225	24.03	67	217	35	187	2.0e-15	76	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
637681117	855	18.14	36	801	18	751	2.0e-31	131	COG3451	Type IV secretory pathway, VirB4 component	796
637681119	196	27.59	59	196	28	169	4.0e-13	68.4	COG4959	Type IV secretory pathway, protease TraF	173
637681135	125	30.1	22	124	1	100	1.0e-11	62.5	COG0789	DNA-binding transcriptional regulator, MerR family	124
637681136	100	49.45	2	92	1	91	5.0e-27	112	COG0776	Bacterial nucleoid DNA-binding protein	94
637681137	794	42.34	143	793	1	650	0.0e+00	611	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
637681138	348	54.73	1	346	3	335	3.0e-124	438	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
637681139	119	73.73	1	118	1	118	3.0e-38	150	COG0292	Ribosomal protein L20	118
637681140	65	56.92	1	65	1	65	3.0e-10	56.8	COG0291	Ribosomal protein L35	65
637681141	137	70.37	1	135	42	176	1.0e-50	191	COG0290	Translation initiation factor IF-3	176
637681142	638	55.96	34	636	1	585	0.0e+00	795	COG0441	Threonyl-tRNA synthetase	589
637681145	335	21.57	7	318	2	308	2.0e-08	53.8	COG2404	Oligoribonuclease NrnB or cAMP/cGMP phosphodiesterase, DHH superfamily	339
637681151	221	47.53	1	218	1	221	7.0e-60	223	COG2135	Putative SOS response-associated peptidase YedK	226
637681160	309	27.04	9	299	12	296	8.0e-20	91.2	COG4643	Uncharacterized domain associated with phage/plasmid primase	366
637681161	504	31.65	1	356	33	400	8.0e-52	198	COG1061	Superfamily II DNA or RNA helicase	442
637681170	404	22.73	85	384	1	303	5.0e-08	52.7	COG0582	Integrase	309
637681172	269	29.81	4	266	19	282	1.0e-37	150	COG1562	Phytoene/squalene synthetase	288
637681173	277	44.29	1	277	7	286	2.0e-64	239	COG1562	Phytoene/squalene synthetase	288
637681174	410	23.45	1	405	1	461	8.0e-31	128	COG3349	Uncharacterized conserved protein, contains NAD-binding domain and a Fe-S cluster	485
637681175	576	38.95	38	566	7	522	0.0e+00	492	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
637681179	405	33.14	16	352	1	335	1.0e-46	180	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637681180	224	60.18	1	224	1	226	6.0e-78	283	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
637681181	200	35.85	14	200	2	213	6.0e-18	84.2	COG2755	Lysophospholipase L1 or related esterase	216
637681182	353	32.67	17	266	18	260	3.0e-33	135	COG2603	tRNA 2-selenouridine synthase SelU, contains rhodanese domain	334
637681184	135	29.6	5	127	4	127	2.0e-20	91.2	COG1765	Uncharacterized OsmC-related protein	137
637681185	905	43.35	4	632	1	595	0.0e+00	518	COG1042	Acyl-CoA synthetase (NDP forming)	598
637681187	468	44.2	32	445	4	391	6.0e-96	344	COG2262	50S ribosomal subunit-associated GTPase HflX	411
637681188	427	51.22	17	426	3	411	0.0e+00	506	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
637681189	376	24.53	1	371	6	361	8.0e-58	217	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
637681190	270	27.63	14	268	15	261	9.0e-33	134	COG3358	Uncharacterized conserved protein, DUF1684 family	262
637681192	143	30.56	6	140	10	148	7.0e-13	66.6	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
637681194	863	55.92	5	851	1	775	0.0e+00	961	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
637681195	544	34.24	178	544	48	408	4.0e-51	196	COG0840	Methyl-accepting chemotaxis protein	408
637681196	150	51.7	1	147	4	149	2.0e-44	171	COG0314	Molybdopterin synthase catalytic subunit	149
637681197	524	64.9	1	523	2	528	0.0e+00	838	COG4108	Peptide chain release factor RF-3	528
637681198	243	23.89	3	238	32	278	9.0e-10	57.6	COG5473	Uncharacterized membrane protein	290
637681200	281	33.46	2	263	13	266	4.0e-44	172	COG0676	D-hexose-6-phosphate mutarotase	287
637681203	281	55.8	2	277	1	274	5.0e-101	360	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
637681205	413	39.17	2	411	4	402	1.0e-74	274	COG1301	Na+/H+-dicarboxylate symporter	415
637681207	173	53.18	1	173	2	174	6.0e-60	223	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
637681209	217	30.7	8	217	5	211	2.0e-24	105	COG4912	3-methyladenine DNA glycosylase AlkD	222
637681210	161	31.11	16	149	1	130	5.0e-16	77.6	COG1699	Flagellar assembly factor FliW	146
637681211	772	60.59	1	772	6	778	0.0e+00	1000	COG2183	Transcriptional accessory protein Tex/SPT6	780
637681212	438	32.66	1	438	5	438	2.0e-73	269	COG4097	Predicted ferric reductase	438
637681214	126	36.61	17	126	6	116	2.0e-23	101	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
637681215	293	33.33	1	283	2	286	3.0e-59	222	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
637681216	455	33.33	117	450	12	335	7.0e-37	148	COG0642	Signal transduction histidine kinase	336
637681217	468	41.9	14	468	2	456	2.0e-97	349	COG0277	FAD/FMN-containing dehydrogenase	459
637681218	440	34.38	8	440	3	436	6.0e-123	434	COG0621	tRNA A37 methylthiotransferase MiaB	437
637681221	1275	35.51	707	981	62	326	4.0e-39	157	COG0642	Signal transduction histidine kinase	336
637681224	291	23.05	18	273	3	247	1.0e-18	86.9	COG3394	Predicted glycoside hydrolase or deacetylase ChbG, UPF0249 family	257
637681225	130	24.59	11	127	16	137	1.0e-06	45.7	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
637681227	362	33.58	52	310	4	261	3.0e-21	96.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
637681228	415	34.2	24	403	20	397	3.0e-65	242	COG3135	Predicted benzoate:H+ symporter BenE	402
637681229	323	44.79	1	321	1	315	1.0e-86	313	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
637681230	146	27.07	7	133	3	135	9.0e-18	83.1	COG2703	Hemerythrin	144
637681233	408	23.45	55	405	9	357	5.0e-39	155	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637681235	189	22.88	1	152	6	155	3.0e-09	55.3	COG3945	Hemerythrin-like domain	189
637681236	237	44.3	3	237	1	237	3.0e-72	265	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
637681237	257	39.76	7	251	2	250	1.0e-65	243	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
637681238	320	37.34	3	312	5	314	1.0e-41	164	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
637681239	288	36.39	1	287	1	292	2.0e-43	169	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
637681240	390	32.58	22	369	2	355	2.0e-45	176	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637681241	262	42.15	3	262	2	262	4.0e-60	224	COG3971	2-keto-4-pentenoate hydratase	264
637681242	260	44.44	1	260	2	262	2.0e-66	245	COG3971	2-keto-4-pentenoate hydratase	264
637681243	486	42	8	486	3	469	2.0e-128	452	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
637681244	309	20.26	2	206	4	216	5.0e-08	52.2	COG2514	Catechol-2,3-dioxygenase	265
637681245	1186	29.06	20	708	1	639	0.0e+00	480	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
637681246	446	23.36	21	446	4	366	7.0e-49	188	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
637681247	162	52.53	5	162	7	164	1.0e-49	189	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
637681248	336	28.42	2	92	1	95	7.0e-09	55.1	COG0633	Ferredoxin	102
637681248	336	30.21	106	336	6	234	1.0e-37	150	COG1018	Ferredoxin-NADP reductase	266
637681249	258	33.72	4	255	2	249	2.0e-37	149	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
637681250	321	33.33	214	318	22	123	3.0e-12	66	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
637681252	228	42.79	7	228	3	224	2.0e-58	218	COG4149	ABC-type molybdate transport system, permease component	225
637681253	359	48.04	4	359	1	352	8.0e-103	367	COG4148	ABC-type molybdate transport system, ATPase component	352
637681254	710	20.9	1	710	1	608	1.0e-26	115	COG4206	Outer membrane cobalamin receptor protein	608
637681256	909	36.3	230	498	73	330	6.0e-42	166	COG0642	Signal transduction histidine kinase	336
637681257	715	48.21	450	700	1	248	1.0e-76	281	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
637681258	675	20.66	16	675	10	699	2.0e-33	138	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
637681259	224	30.57	4	222	9	235	4.0e-19	88.6	COG3471	Predicted secreted (periplasmic) protein	235
637681260	84	35.44	1	78	1	79	2.0e-06	44.3	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
637681261	295	33.45	3	293	2	292	2.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
637681262	264	40.98	1	261	6	266	4.0e-59	221	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
637681263	174	44.25	1	173	6	179	3.0e-37	148	COG3038	Cytochrome b561	181
637681264	184	29.47	1	182	3	192	2.0e-27	115	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
637681265	189	46.07	1	189	1	191	2.0e-40	158	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
637681266	182	36.26	4	182	1	176	1.0e-28	119	COG0431	NAD(P)H-dependent FMN reductase	184
637681269	356	25	8	349	11	361	2.0e-07	50.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
637681270	1028	47.7	1	1015	1	1019	0.0e+00	1046	COG3696	Cu/Ag efflux pump CusA	1027
637681272	414	23.08	31	414	47	449	7.0e-14	72.1	COG1538	Outer membrane protein TolC	457
637681276	503	50.8	5	503	4	499	0.0e+00	589	COG0427	Acyl-CoA hydrolase	501
637681278	315	28.08	6	315	1	296	1.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
637681280	1023	32.19	548	866	20	326	2.0e-40	161	COG0642	Signal transduction histidine kinase	336
637681283	201	31.52	1	169	2	183	1.0e-23	103	COG3658	Cytochrome b	192
637681284	218	48.21	1	214	1	223	1.0e-57	215	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
637681285	449	30.77	122	431	10	317	5.0e-39	155	COG0642	Signal transduction histidine kinase	336
637681292	444	30.43	18	432	5	419	6.0e-58	218	COG1169	Isochorismate synthase EntC	423
637681293	693	53.91	8	693	4	689	0.0e+00	921	COG0855	Polyphosphate kinase	696
637681294	548	41.53	361	542	1	181	1.0e-42	167	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
637681296	740	50.41	13	739	8	700	0.0e+00	757	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
637681297	294	24.49	1	294	1	288	3.0e-08	52.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
637681298	261	49.39	20	260	22	266	4.0e-75	274	COG3228	Mlc titration factor MtfA, regulates ptsG expression	266
637681299	257	24.48	1	252	2	282	5.0e-17	81.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
637681300	284	25.72	17	281	10	279	4.0e-19	89	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
637681301	772	39.11	511	769	34	293	1.0e-53	205	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
637681302	182	24.18	2	178	6	177	4.0e-16	78	COG3216	Uncharacterized conserved protein, DUF2062 family	184
637681303	671	34.83	293	671	33	408	5.0e-53	202	COG0840	Methyl-accepting chemotaxis protein	408
637681304	225	47.3	5	225	1	222	3.0e-73	268	COG1136	ABC-type lipoprotein export system, ATPase component	226
637681305	415	48.68	1	415	1	408	6.0e-114	404	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
637681306	345	26.22	70	330	60	312	8.0e-23	101	COG4255	Uncharacterized protein	318
637681307	566	45	35	532	1	472	2.0e-106	380	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
637681308	336	26.42	3	308	1	310	1.0e-40	160	COG0167	Dihydroorotate dehydrogenase	310
637681309	1212	29.38	423	630	1	200	4.0e-31	130	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
637681309	1212	37.63	4	389	2	361	3.0e-87	317	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
637681312	397	28.85	32	395	47	407	2.0e-38	153	COG0840	Methyl-accepting chemotaxis protein	408
637681313	325	63.18	88	325	1	239	4.0e-99	354	COG1186	Protein chain release factor B	239
637681316	764	37.23	339	618	66	336	2.0e-40	161	COG0642	Signal transduction histidine kinase	336
637681317	501	59.48	10	501	6	501	0.0e+00	695	COG1190	Lysyl-tRNA synthetase (class II)	502
637681319	644	23.34	241	627	1	387	8.0e-32	132	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
637681319	644	35.56	1	229	3	239	1.0e-56	214	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
637681320	423	65.01	1	423	6	426	0.0e+00	661	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
637681325	371	47.75	14	369	12	367	1.0e-123	436	COG1485	Predicted ATPase	367
637681326	474	46.58	1	464	1	454	0.0e+00	492	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
637681327	407	51.71	2	405	1	403	1.0e-107	383	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
637681328	945	57.45	4	941	1	905	0.0e+00	1286	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
637681329	432	50.62	28	431	1	390	0.0e+00	486	COG0372	Citrate synthase	390
637681330	80	40.28	8	79	17	87	3.0e-10	56.8	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
637681331	236	53.62	4	236	1	232	7.0e-81	293	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
637681332	594	49.74	3	579	2	561	0.0e+00	600	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
637681333	115	35.65	1	115	2	116	1.0e-15	75.2	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
637681334	129	33.33	7	128	1	126	1.0e-13	69.2	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
637681335	251	43.57	13	250	1	236	1.0e-48	186	COG2188	DNA-binding transcriptional regulator, GntR family	236
637681336	328	30.37	6	328	1	311	3.0e-60	225	COG0039	Malate/lactate dehydrogenase	313
637681337	327	26.09	25	318	7	283	8.0e-27	114	COG2301	Citrate lyase beta subunit	283
637681338	242	37.44	2	225	75	286	3.0e-51	195	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
637681339	146	32.74	13	123	7	117	1.0e-11	62.9	COG0517	CBS domain	117
637681342	415	23.26	8	306	6	255	2.0e-26	113	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
637681343	386	28.57	1	384	8	395	9.0e-39	154	COG3213	Uncharacterized protein involved in response to NO	396
637681344	340	50.86	23	313	4	291	3.0e-96	345	COG3129	23S rRNA A1618 N6-methylase RlmF	292
637681345	282	30.74	10	275	3	237	9.0e-52	197	COG0688	Phosphatidylserine decarboxylase	239
637681347	327	20.37	97	312	29	223	1.0e-13	71	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
637681348	150	58.5	1	147	2	146	9.0e-49	185	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
637681350	367	24.23	1	281	3	269	2.0e-15	76.7	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
637681351	862	75.15	1	860	1	850	0.0e+00	1409	COG1049	Aconitase B	852
637681352	537	30.71	171	537	44	408	5.0e-40	159	COG0840	Methyl-accepting chemotaxis protein	408
637681353	117	26.5	5	112	6	114	7.0e-07	46.1	COG0727	Fe-S-cluster containining protein	132
637681354	226	21.7	29	221	11	220	2.0e-14	73	COG0220	tRNA G46 methylase TrmB	227
637681355	319	34.5	1	306	10	314	1.0e-62	233	COG0042	tRNA-dihydrouridine synthase	323
637681356	142	27.48	2	130	1	130	7.0e-13	66.5	COG1569	Predicted nucleic acid-binding protein, contains PIN domain	142
637681357	311	27.02	1	304	48	351	1.0e-57	216	COG1740	Ni,Fe-hydrogenase I small subunit	355
637681358	505	30.76	1	500	1	537	2.0e-95	343	COG0374	Ni,Fe-hydrogenase I large subunit	545
637681359	1053	36.49	5	148	2	149	3.0e-20	94.6	COG0680	Ni,Fe-hydrogenase maturation factor	160
637681359	1053	41.44	365	625	83	333	2.0e-42	168	COG0642	Signal transduction histidine kinase	336
637681360	858	35.62	266	569	32	326	5.0e-40	159	COG0642	Signal transduction histidine kinase	336
637681361	377	22	49	148	6	103	2.0e-08	53.4	COG0607	Rhodanese-related sulfurtransferase	110
637681361	377	22.27	153	341	13	247	7.0e-10	58.8	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
637681362	257	54.09	1	257	1	253	3.0e-84	304	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
637681364	453	44.44	6	452	2	446	0.0e+00	473	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
637681365	304	27.24	4	290	3	279	1.0e-18	87.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
637681366	387	44.73	1	386	2	387	6.0e-112	397	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
637681367	237	27.24	4	235	23	279	7.0e-14	70.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
637681369	221	45.15	1	206	1	206	6.0e-61	227	COG0132	Dethiobiotin synthetase	223
637681370	112	26.17	6	111	8	114	8.0e-06	42.4	COG2198	HPt (histidine-containing phosphotransfer) domain	122
637681371	350	44.25	3	344	16	360	6.0e-89	321	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
637681372	202	46.53	1	202	1	177	2.0e-44	172	COG2917	Intracellular septation protein A	180
637681373	100	50	1	98	1	92	2.0e-21	94.2	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
637681374	88	42.53	1	87	3	86	5.0e-16	75.8	COG0271	Stress-induced morphogen (activity unknown)	90
637681376	439	20.63	34	435	4	404	5.0e-29	122	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
637681377	422	29.9	17	420	1	401	2.0e-49	189	COG3420	Nitrous oxidase accessory protein NosD, contains tandem CASH domains	408
637681378	281	27.89	10	257	13	256	3.0e-31	128	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
637681379	313	27.67	1	298	1	294	6.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
637681380	266	30.71	12	265	9	252	3.0e-11	62.7	COG0730	Uncharacterized membrane protein YfcA	258
637681381	557	36.98	1	540	1	510	0.0e+00	489	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
637681382	169	43.6	1	169	3	166	8.0e-36	143	COG3749	Uncharacterized conserved protein, DUF934 family	167
637681383	239	41.33	17	236	21	241	2.0e-51	196	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
637681387	159	38.13	1	138	1	139	3.0e-29	121	COG1959	DNA-binding transcriptional regulator, IscR family	150
637681388	467	35.52	24	419	1	370	3.0e-72	266	COG0348	Polyferredoxin	386
637681389	1008	17.28	69	714	1	547	9.0e-31	129	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
637681390	772	23.33	10	186	1	180	5.0e-13	70.3	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
637681390	772	47.9	170	569	2	396	2.0e-130	460	COG0282	Acetate kinase	396
637681390	772	53.76	581	765	22	207	6.0e-62	232	COG4869	Propanediol utilization protein	210
637681392	450	48.03	1	449	2	455	0.0e+00	491	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
637681394	175	29.57	1	175	5	190	1.0e-26	113	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
637681395	177	20.59	9	173	16	185	1.0e-06	46.8	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
637681398	443	17.28	45	329	27	314	2.0e-10	61.1	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
637681400	129	43.44	8	126	1	122	1.0e-22	98.9	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
637681401	578	34.64	6	408	8	383	5.0e-79	289	COG1944	Ribosomal protein S12 methylthiotransferase accessory factor YcaO	398
637681402	540	33.68	152	540	24	408	1.0e-43	171	COG0840	Methyl-accepting chemotaxis protein	408
637681403	955	37.19	526	809	61	334	3.0e-42	167	COG0642	Signal transduction histidine kinase	336
637681403	955	39.29	36	287	47	296	2.0e-55	211	COG3452	Extracellular (periplasmic) sensor domain CHASE (specificity unknown)	297
637681404	468	66.02	5	466	1	462	0.0e+00	721	COG0114	Fumarate hydratase class II	462
637681412	172	41.28	6	169	8	178	6.0e-33	133	COG2032	Cu/Zn superoxide dismutase	179
637681413	309	33.12	1	309	10	261	3.0e-45	176	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
637681414	426	55.61	10	426	2	413	0.0e+00	559	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
637681415	777	30.67	288	610	12	326	7.0e-37	149	COG0642	Signal transduction histidine kinase	336
637681416	367	27.7	14	348	1	341	2.0e-38	153	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637681418	351	31.13	58	351	15	316	1.0e-51	197	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
637681419	180	33.76	6	155	19	175	2.0e-22	99.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
637681421	645	19.42	32	642	36	696	1.0e-29	125	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
637681422	700	20.32	17	699	38	768	2.0e-38	154	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
637681426	389	31.06	12	374	10	372	4.0e-30	126	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
637681427	1029	37.82	2	1015	1	1009	0.0e+00	912	COG0841	Multidrug efflux pump subunit AcrB	1009
637681430	490	34.46	106	484	102	485	5.0e-77	282	COG0260	Leucyl aminopeptidase	485
637681431	172	28.82	1	148	3	172	4.0e-19	87.6	COG1335	Nicotinamidase-related amidase	205
637681432	190	58.62	14	187	12	185	1.0e-62	232	COG3310	Uncharacterized protein	196
637681435	378	43.89	197	376	6	181	1.0e-38	154	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
637681436	264	34.36	41	264	2	228	5.0e-44	171	COG3821	Uncharacterized membrane protein	234
637681437	295	44.67	3	293	2	291	1.0e-65	243	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
637681438	243	47.92	5	243	23	258	3.0e-61	228	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
637681439	187	22.97	39	186	11	138	2.0e-06	45.7	COG2703	Hemerythrin	144
637681441	805	47.67	26	725	3	706	0.0e+00	727	COG0557	Exoribonuclease R	706
637681445	435	60.28	3	434	2	429	0.0e+00	630	COG0104	Adenylosuccinate synthase	430
637681446	384	38.27	1	383	1	390	6.0e-69	254	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
637681447	61	41.67	1	60	1	60	5.0e-08	49.5	COG3242	Uncharacterized conserved protein YjeT, DUF2065 family	62
637681448	295	29.49	4	289	2	291	1.0e-46	180	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
637681449	436	28.05	76	374	1	291	4.0e-44	172	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
637681450	384	53.54	6	358	1	353	7.0e-113	400	COG2262	50S ribosomal subunit-associated GTPase HflX	411
637681451	78	71.05	3	77	2	77	7.0e-24	101	COG1923	sRNA-binding regulator protein Hfq	77
637681452	443	49.66	1	439	2	444	0.0e+00	549	COG1160	Predicted GTPases	444
637681453	386	24.56	28	296	20	294	9.0e-22	98.4	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
637681454	212	38.94	4	210	3	207	2.0e-31	128	COG2976	Putative negative regulator of RcsB-dependent stress response	207
637681455	429	49.07	3	422	2	428	0.0e+00	479	COG0124	Histidyl-tRNA synthetase	429
637681456	409	45.16	6	408	3	360	3.0e-127	448	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
637681457	311	23.49	23	280	4	284	5.0e-22	98.6	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
637681458	266	35.34	32	263	20	249	7.0e-43	167	COG3063	Tfp pilus assembly protein PilF	250
637681459	364	55.27	3	351	2	349	0.0e+00	460	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
637681460	142	58.96	2	135	1	134	1.0e-54	205	COG0105	Nucleoside diphosphate kinase	135
637681462	427	46.97	47	425	1	379	2.0e-98	352	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
637681463	260	29.73	1	185	7	161	7.0e-20	91.2	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
637681464	334	43.26	5	321	7	324	3.0e-90	325	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
637681465	449	51.82	3	410	1	405	1.0e-106	380	COG1301	Na+/H+-dicarboxylate symporter	415
637681467	198	52.6	1	192	2	193	7.0e-56	210	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
637681469	419	72.32	1	419	4	421	0.0e+00	688	COG1158	Transcription termination factor Rho	422
637681470	74	61.33	1	73	1	75	3.0e-22	96.9	COG0254	Ribosomal protein L31	75
637681471	540	24.26	9	459	1	450	3.0e-16	80.2	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
637681472	184	62.64	1	182	1	182	2.0e-77	281	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
637681473	416	23.76	137	409	33	293	6.0e-20	92.3	COG0501	Zn-dependent protease with chaperone function	302
637681475	289	42.32	1	282	4	288	2.0e-78	285	COG1162	Putative ribosome biogenesis GTPase RsgA	301
637681476	361	48.09	1	360	10	359	4.0e-96	345	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
637681477	1560	34.33	941	1207	71	326	1.0e-39	159	COG0642	Signal transduction histidine kinase	336
637681478	402	36.89	1	401	2	408	9.0e-108	383	COG2081	Predicted flavoprotein YhiN	408
637681479	321	32.17	3	309	10	316	3.0e-39	156	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
637681480	839	28.09	511	832	1	313	1.0e-45	178	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
637681480	839	44.97	9	495	5	487	0.0e+00	559	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
637681481	1117	30.79	1	301	9	318	4.0e-35	144	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
637681481	1117	52.3	286	1116	3	804	0.0e+00	905	COG4196	Uncharacterized conserved protein, DUF2126 family	808
637681485	306	26.7	9	213	3	202	3.0e-14	73	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
637681486	154	28.78	15	152	7	144	2.0e-15	75.1	COG3909	Cytochrome c556	147
637681487	546	42.46	5	536	1	485	0.0e+00	524	COG2509	Uncharacterized FAD-dependent dehydrogenase	486
637681489	404	44.66	1	404	2	403	2.0e-129	455	COG2081	Predicted flavoprotein YhiN	408
637681491	315	39.81	1	314	1	313	2.0e-72	266	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
637681492	487	58.65	14	487	5	478	0.0e+00	676	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
637681493	393	38.46	2	392	1	391	2.0e-73	269	COG0183	Acetyl-CoA acetyltransferase	392
637681494	307	32.59	3	307	10	319	3.0e-35	142	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
637681495	198	22.95	41	153	17	134	1.0e-05	43.4	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
637681498	237	32.31	1	193	1	192	1.0e-33	136	COG0518	GMP synthase - Glutamine amidotransferase domain	198
637681499	164	50	1	164	4	165	8.0e-39	153	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
637681500	103	41.76	12	102	3	93	5.0e-28	115	COG3123	Uncharacterized conserved protein YaiE, UPF0345 family	94
637681502	468	55.85	1	408	1	402	0.0e+00	564	COG0137	Argininosuccinate synthase	403
637681503	306	51.79	1	300	4	309	7.0e-116	410	COG0078	Ornithine carbamoyltransferase	310
637681504	390	45.8	1	390	14	402	1.0e-127	449	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
637681506	89	52.27	1	88	1	88	8.0e-10	55.3	COG0268	Ribosomal protein S20	88
637681507	1544	23.42	569	1478	105	958	1.0e-64	243	COG3419	Tfp pilus assembly protein, tip-associated adhesin PilY1	1036
637681511	177	26.97	5	169	2	174	1.0e-13	69.7	COG4970	Tfp pilus assembly protein FimT	181
637681512	138	32.87	1	130	2	139	4.0e-19	87.4	COG4968	Tfp pilus assembly protein PilE	139
637681514	306	64.51	1	292	2	294	5.0e-118	417	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
637681515	143	34.29	4	142	2	140	3.0e-24	104	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
637681516	159	45.16	7	157	13	163	1.0e-32	132	COG0597	Lipoprotein signal peptidase	167
637681517	932	47.19	3	926	2	933	0.0e+00	1136	COG0060	Isoleucyl-tRNA synthetase	933
637681518	306	48.86	1	305	1	304	1.0e-93	336	COG0196	FAD synthase	304
637681519	346	36.21	155	324	23	181	8.0e-30	124	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
637681520	449	37.82	196	433	26	228	6.0e-51	195	COG0860	N-acetylmuramoyl-L-alanine amidase	231
637681521	153	47.1	1	137	12	149	3.0e-41	160	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
637681522	354	53.22	12	345	1	337	1.0e-95	343	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
637681523	523	47.22	335	513	1	179	2.0e-45	177	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
637681526	279	42.86	1	278	7	281	7.0e-66	244	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
637681528	283	21.48	32	280	43	289	7.0e-07	48	COG5006	Threonine/homoserine efflux transporter RhtA	292
637681529	393	20.44	31	387	3	357	9.0e-32	131	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
637681530	79	46.67	4	63	5	64	5.0e-08	49.6	COG1722	Exonuclease VII small subunit	81
637681531	297	36.04	4	297	1	322	1.0e-60	226	COG0142	Geranylgeranyl pyrophosphate synthase	322
637681532	618	60.77	6	618	4	625	0.0e+00	916	COG1154	Deoxyxylulose-5-phosphate synthase	627
637681533	270	38.95	5	264	2	285	8.0e-66	243	COG1469	GTP cyclohydrolase FolE2	289
637681534	126	65.52	1	116	3	115	2.0e-38	151	COG0335	Ribosomal protein L19	115
637681535	254	55.69	2	246	1	239	1.0e-95	342	COG0336	tRNA G37 N-methylase TrmD	240
637681536	170	36.26	1	170	2	172	6.0e-38	150	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
637681537	84	55.95	1	84	1	83	8.0e-25	105	COG0228	Ribosomal protein S16	87
637681539	275	28.79	18	269	23	284	5.0e-24	105	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
637681540	198	32.06	1	197	3	207	2.0e-28	119	COG0655	Multimeric flavodoxin WrbA	207
637681541	122	50.48	6	108	15	118	1.0e-18	85.4	COG3308	Uncharacterized membrane protein	131
637681542	513	51.08	3	415	1	409	3.0e-124	438	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
637681543	250	41.85	18	242	6	228	2.0e-43	169	COG1183	Phosphatidylserine synthase	234
637681544	338	64.29	1	336	3	338	0.0e+00	530	COG0059	Ketol-acid reductoisomerase	338
637681545	163	55.28	1	161	3	163	2.0e-49	188	COG0440	Acetolactate synthase, small subunit	163
637681546	566	48.85	2	561	1	550	0.0e+00	660	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
637681547	192	27.12	15	190	20	180	1.0e-17	83.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
637681550	137	31.34	5	136	17	150	5.0e-06	43.6	COG1714	Uncharacterized membrane protein YckC, RDD family	172
637681551	362	32.42	5	362	1	364	4.0e-49	189	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
637681552	360	28.89	1	348	2	361	7.0e-43	168	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
637681553	498	50.7	1	495	1	485	0.0e+00	563	COG0260	Leucyl aminopeptidase	485
637681554	140	32.09	1	130	1	134	9.0e-22	96.1	COG2927	DNA polymerase III, chi subunit	144
637681556	943	51	3	942	1	877	0.0e+00	1163	COG0525	Valyl-tRNA synthetase	877
637681558	555	29.65	357	551	33	257	3.0e-20	93.6	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
637681559	75	43.42	1	75	2	77	4.0e-17	79.9	COG0425	TusA-related sulfurtransferase	78
637681560	483	33.97	9	481	17	484	1.0e-84	307	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
637681561	160	61.29	6	160	4	157	6.0e-57	213	COG0315	Molybdenum cofactor biosynthesis enzyme	157
637681562	157	32.05	6	157	1	148	2.0e-20	92	COG5501	Predicted secreted protein	148
637681564	72	62.69	6	72	1	67	6.0e-26	109	COG1278	Cold shock protein, CspA family	67
637681565	102	48.51	1	101	6	106	2.0e-31	127	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
637681566	753	47.58	1	747	1	786	0.0e+00	865	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
637681567	163	45.68	3	163	11	172	5.0e-44	170	COG0684	Regulator of RNase E activity RraA	210
637681568	602	26.33	36	430	19	408	5.0e-45	176	COG0840	Methyl-accepting chemotaxis protein	408
637681569	432	72.12	1	431	1	433	0.0e+00	658	COG2224	Isocitrate lyase	433
637681570	1038	21.22	29	302	31	293	1.0e-18	89.2	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
637681571	300	29.33	3	297	2	297	2.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
637681572	532	44.49	1	532	7	542	0.0e+00	547	COG2225	Malate synthase	545
637681576	119	38.18	1	110	7	116	1.0e-15	75.6	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
637681577	239	50.44	11	238	2	228	7.0e-56	210	COG1346	Putative effector of murein hydrolase	230
637681579	202	57.29	7	198	6	197	2.0e-64	238	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
637681581	344	27.22	94	253	66	234	4.0e-14	72.6	COG0666	Ankyrin repeat	235
637681583	541	36.65	193	541	60	408	9.0e-51	195	COG0840	Methyl-accepting chemotaxis protein	408
637681584	399	42.36	1	399	1	396	4.0e-115	408	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
637681585	269	41.54	11	266	5	264	1.0e-66	246	COG0796	Glutamate racemase	269
637681587	164	20.39	21	164	5	155	1.0e-15	76.4	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
637681590	413	66.67	20	413	15	406	0.0e+00	593	COG0538	Isocitrate dehydrogenase	407
637681591	745	71.6	1	743	1	742	0.0e+00	1228	COG2838	Monomeric isocitrate dehydrogenase	744
637681592	593	43.1	12	590	6	577	0.0e+00	645	COG4579	Isocitrate dehydrogenase kinase/phosphatase	578
637681593	380	47.08	4	362	1	356	8.0e-95	340	COG3288	NAD/NADP transhydrogenase alpha subunit	356
637681595	456	42.4	7	452	6	463	6.0e-114	404	COG1282	NAD/NADP transhydrogenase beta subunit	463
637681599	573	26.33	102	534	36	471	1.0e-56	214	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
637681603	155	36.77	6	155	1	148	7.0e-25	106	COG5501	Predicted secreted protein	148
637681604	348	44.12	246	346	4	105	2.0e-17	83.6	COG4654	Cytochrome c551/c552	110
637681605	448	28.68	34	298	2	231	2.0e-25	110	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
637681606	106	37.23	8	100	12	105	4.0e-11	59.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
637681607	101	39.22	1	101	1	101	5.0e-08	49.2	COG2863	Cytochrome c553	121
637681608	425	21.31	35	371	1	326	3.0e-24	106	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
637681609	205	28.33	9	128	6	121	2.0e-15	76.2	COG2863	Cytochrome c553	121
637681610	200	36.44	6	123	4	120	3.0e-18	85	COG2863	Cytochrome c553	121
637681611	149	48.99	1	148	1	147	8.0e-46	176	COG0756	dUTPase	148
637681612	396	50.38	3	392	2	390	4.0e-110	392	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
637681613	226	53.54	1	226	1	224	5.0e-71	260	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
637681614	77	68.83	1	76	1	77	7.0e-22	95.4	COG0227	Ribosomal protein L28	77
637681615	55	56	4	53	1	50	6.0e-10	56	COG0267	Ribosomal protein L33	50
637681616	165	28.75	8	165	12	169	1.0e-11	62.7	COG1495	Disulfide bond formation protein DsbB	170
637681617	234	49.35	4	232	2	229	4.0e-58	217	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
637681618	478	31.86	165	478	22	331	3.0e-36	146	COG0642	Signal transduction histidine kinase	336
637681621	200	27.53	21	198	19	182	6.0e-20	90.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
637681624	280	54.01	8	279	5	277	6.0e-87	314	COG3220	Uncharacterized conserved protein, UPF0276 family	282
637681625	246	29.75	7	246	6	235	4.0e-41	161	COG3219	Uncharacterized protein	237
637681628	714	21.27	12	583	8	564	2.0e-31	131	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
637681630	420	44.13	109	419	40	354	1.0e-78	287	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
637681632	215	58.29	2	200	1	199	1.0e-74	272	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
637681634	213	37.76	14	208	1	194	2.0e-31	129	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
637681635	615	43.12	9	614	1	638	0.0e+00	615	COG0323	DNA mismatch repair ATPase MutL	638
637681640	567	61.04	1	403	1	401	2.0e-120	426	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
637681641	294	37.16	150	292	2	149	2.0e-12	66.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
637681642	314	47.88	5	311	1	305	4.0e-91	327	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
637681645	347	59.25	4	347	1	345	0.0e+00	471	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
637681646	424	51.42	3	423	2	400	0.0e+00	461	COG0162	Tyrosyl-tRNA synthetase	401
637681647	226	42.29	1	225	1	226	4.0e-56	210	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
637681648	474	29.97	150	473	7	328	1.0e-42	168	COG0642	Signal transduction histidine kinase	336
637681650	449	39.78	5	447	6	442	6.0e-100	358	COG4452	Inner membrane protein involved in colicin E2 resistance	443
637681652	222	27.85	1	219	5	203	5.0e-33	134	COG0560	Phosphoserine phosphatase	212
637681653	447	35.42	31	436	1	410	3.0e-79	289	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
637681654	158	56.33	1	158	1	158	2.0e-53	201	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
637681655	120	65.77	9	119	6	115	9.0e-36	141	COG3169	Uncharacterized conserved protein, DUF486 family	116
637681656	272	54.34	9	272	1	265	3.0e-94	338	COG0413	Ketopantoate hydroxymethyltransferase	268
637681657	274	52.48	1	274	1	282	5.0e-98	351	COG0414	Panthothenate synthetase	285
637681658	127	56	2	126	1	125	2.0e-45	174	COG0853	Aspartate 1-decarboxylase	126
637681660	421	25.7	9	174	7	178	2.0e-10	60.8	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
637681663	201	33.51	12	200	20	206	2.0e-26	112	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
637681665	260	24.3	26	256	45	291	2.0e-24	105	COG0714	MoxR-like ATPase	329
637681668	612	33.44	1	611	7	637	1.0e-109	390	COG4548	Nitric oxide reductase activation protein	637
637681669	231	28.57	12	220	1	210	3.0e-28	118	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
637681672	471	24.91	186	454	89	347	3.0e-12	66.9	COG1566	Multidrug resistance efflux pump	352
637681673	725	34.87	23	714	11	696	0.0e+00	554	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
637681674	688	61.63	1	688	2	700	0.0e+00	772	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
637681675	419	26.36	2	365	1	328	1.0e-50	194	COG0205	6-phosphofructokinase	347
637681676	217	38.01	1	217	1	178	6.0e-46	177	COG0563	Adenylate kinase or related kinase	178
637681677	261	57.03	6	254	4	242	1.0e-86	312	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
637681678	58	58.93	1	56	1	56	1.0e-14	71.4	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
637681679	333	47.75	5	327	4	328	1.0e-86	313	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
637681680	137	29.71	1	136	1	134	9.0e-25	106	COG0848	Biopolymer transport protein ExbD	137
637681681	201	29.56	1	200	12	213	3.0e-30	125	COG0811	Biopolymer transport protein ExbB/TolQ	216
637681682	450	45.66	9	443	2	436	4.0e-123	435	COG1570	Exonuclease VII, large subunit	440
637681683	194	51.76	1	194	2	199	5.0e-67	247	COG0605	Superoxide dismutase	204
637681684	222	43.35	19	220	5	207	1.0e-50	192	COG2860	Uncharacterized membrane protein YeiH	209
637681685	734	37.3	144	569	1	397	8.0e-96	345	COG1944	Ribosomal protein S12 methylthiotransferase accessory factor YcaO	398
637681686	431	36.09	2	431	6	427	3.0e-83	302	COG1253	Hemolysin or related protein, contains CBS domains	429
637681687	667	29.81	27	594	20	539	9.0e-51	195	COG4796	Type II secretory pathway, component HofQ	709
637681688	159	26.09	1	159	2	149	6.0e-13	67	COG2165	Type II secretory pathway, pseudopilin PulG	149
637681690	177	24.17	16	132	7	124	4.0e-08	51.6	COG2165	Type II secretory pathway, pseudopilin PulG	149
637681692	156	48.25	25	156	7	149	3.0e-22	98.2	COG2165	Type II secretory pathway, pseudopilin PulG	149
637681693	394	40.91	1	394	2	397	3.0e-76	279	COG1459	Type II secretory pathway, component PulF	397
637681694	564	43.84	56	562	2	499	0.0e+00	488	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
637681700	527	33.68	61	527	59	479	9.0e-82	298	COG1785	Alkaline phosphatase	482
637681701	289	27.62	10	289	5	281	8.0e-17	81.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
637681702	228	36.17	8	228	1	234	1.0e-36	146	COG0412	Dienelactone hydrolase	236
637681703	145	34.78	3	139	2	138	1.0e-24	105	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
637681704	139	29.71	2	139	1	137	7.0e-17	79.7	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
637681705	248	51.46	8	245	2	236	9.0e-81	293	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
637681706	597	35.42	1	316	1	314	1.0e-52	201	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
637681706	597	53.6	347	595	2	250	8.0e-85	308	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
637681707	349	30.52	1	339	1	285	5.0e-30	125	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
637681708	333	34.55	104	322	10	219	3.0e-38	152	COG0543	NAD(P)H-flavin reductase	252
637681709	353	24.43	5	346	1	351	4.0e-57	215	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
637681710	314	73.57	1	314	1	307	1.0e-124	439	COG4569	Acetaldehyde dehydrogenase (acetylating)	310
637681711	599	24.37	40	582	13	527	2.0e-54	207	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
637681712	381	31.15	24	377	6	359	9.0e-42	164	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637681713	260	41.38	1	260	2	262	3.0e-61	228	COG3971	2-keto-4-pentenoate hydratase	264
637681714	334	28.7	22	324	14	336	2.0e-44	173	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
637681715	264	32.82	4	258	3	250	3.0e-35	142	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
637681716	178	28.22	12	174	2	160	2.0e-20	92.3	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
637681717	456	22.38	31	368	1	314	4.0e-36	146	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
637681718	114	30.48	1	104	2	106	4.0e-16	76.5	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
637681721	273	28.62	7	273	1	280	1.0e-26	113	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
637681722	205	18.89	21	199	11	190	1.0e-06	47	COG1309	DNA-binding transcriptional regulator, AcrR family	201
637681723	176	32.72	16	172	16	168	2.0e-16	78.8	COG3161	4-hydroxybenzoate synthetase (chorismate-pyruvate lyase)	174
637681724	147	35.09	24	137	4	117	2.0e-29	121	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
637681728	414	55.91	1	220	1	206	2.0e-62	233	COG2715	Spore maturation protein SpmA (function unknown)	206
637681729	288	30.27	83	267	55	216	1.0e-21	97	COG3786	L,D-peptidoglycan transpeptidase YkuD, ErfK/YbiS/YcfS/YnhG family	217
637681730	228	30.18	1	221	2	206	1.0e-34	140	COG0400	Predicted esterase	207
637681732	528	25.62	10	120	25	144	2.0e-09	57.7	COG2010	Cytochrome c, mono- and diheme variants	150
637681733	379	32.04	19	377	13	347	4.0e-53	202	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
637681734	764	40.87	170	743	3	565	0.0e+00	501	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
637681736	751	21.62	164	479	1	317	4.0e-22	100	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
637681737	857	22.29	149	464	1	314	1.0e-31	131	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
637681737	857	26.33	469	855	90	461	5.0e-40	160	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
637681738	270	25.83	16	270	1	266	3.0e-32	132	COG1018	Ferredoxin-NADP reductase	266
637681739	158	19.62	1	156	5	154	3.0e-15	74.7	COG1522	DNA-binding transcriptional regulator, Lrp family	154
637681740	152	25.78	1	125	3	127	2.0e-11	62	COG1522	DNA-binding transcriptional regulator, Lrp family	154
637681741	322	28.06	162	298	1	131	9.0e-15	74.7	COG1522	DNA-binding transcriptional regulator, Lrp family	154
637681744	116	32.11	19	116	21	128	3.0e-15	73.9	COG3794	Plastocyanin	128
637681746	561	22.66	7	130	16	132	5.0e-07	50	COG2010	Cytochrome c, mono- and diheme variants	150
637681747	254	56.5	7	252	1	244	1.0e-88	319	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
637681750	352	53.91	3	344	1	344	0.0e+00	460	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
637681751	369	61.58	3	369	1	366	0.0e+00	548	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
637681752	108	53.85	18	108	7	97	2.0e-24	103	COG1862	Preprotein translocase subunit YajC	97
637681753	625	52.19	105	604	16	501	0.0e+00	479	COG0342	Preprotein translocase subunit SecD	506
637681754	314	46.41	1	305	1	304	3.0e-81	295	COG0341	Preprotein translocase subunit SecF	305
637681755	231	33.51	9	189	6	190	4.0e-30	124	COG3658	Cytochrome b	192
637681757	856	34.35	385	711	5	327	1.0e-42	168	COG0642	Signal transduction histidine kinase	336
637681758	362	42.48	18	351	16	352	3.0e-75	275	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
637681759	105	45.54	1	100	1	101	6.0e-23	99	COG4390	Uncharacterized protein	106
637681761	455	33.85	12	455	1	435	2.0e-103	369	COG0015	Adenylosuccinate lyase	438
637681762	202	31.03	1	197	1	200	3.0e-32	131	COG0625	Glutathione S-transferase	211
637681764	365	57.38	1	364	1	352	2.0e-127	449	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
637681766	151	30.36	7	117	9	119	3.0e-10	57.7	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
637681767	306	44.37	7	296	1	284	3.0e-76	278	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
637681768	62	50	2	53	11	60	7.0e-10	55.8	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
637681769	337	38.05	1	336	1	331	2.0e-67	249	COG0859	ADP-heptose:LPS heptosyltransferase	334
637681771	318	40.25	7	314	23	338	2.0e-77	282	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
637681772	458	34.65	8	450	9	460	2.0e-100	360	COG1109	Phosphomannomutase	464
637681773	417	33.09	10	410	4	403	3.0e-73	269	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
637681776	871	56.48	1	871	6	879	0.0e+00	1160	COG0013	Alanyl-tRNA synthetase	879
637681778	247	35.22	6	233	6	250	5.0e-39	154	COG0584	Glycerophosphoryl diester phosphodiesterase	257
637681779	436	23.53	9	427	5	433	9.0e-29	121	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
637681781	845	33.03	514	839	23	328	4.0e-53	203	COG0642	Signal transduction histidine kinase	336
637681783	507	43.67	10	477	16	479	6.0e-119	421	COG0513	Superfamily II DNA and RNA helicase	513
637681784	265	32.78	12	247	16	253	3.0e-38	152	COG0631	Serine/threonine protein phosphatase PrpC	262
637681785	297	24.49	13	297	2	283	5.0e-27	115	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
637681786	411	27.86	18	411	4	386	6.0e-59	221	COG0247	Fe-S oxidoreductase	388
637681787	349	24.53	4	347	42	457	6.0e-36	145	COG0277	FAD/FMN-containing dehydrogenase	459
637681788	496	42.42	21	472	1	459	3.0e-91	329	COG0277	FAD/FMN-containing dehydrogenase	459
637681789	257	59.22	1	255	1	254	7.0e-99	353	COG3622	Hydroxypyruvate isomerase	260
637681790	196	46.99	14	194	1	183	7.0e-52	196	COG2096	Cob(I)alamin adenosyltransferase	184
637681792	273	35.69	3	271	1	257	1.0e-50	193	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
637681793	102	52.5	24	102	27	106	2.0e-16	77.8	COG4654	Cytochrome c551/c552	110
637681794	495	20.66	15	226	1	212	3.0e-20	93.4	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
637681795	576	19.27	56	162	38	144	1.0e-07	52.3	COG2010	Cytochrome c, mono- and diheme variants	150
637681796	359	65.9	6	353	2	350	0.0e+00	567	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
637681797	368	44.52	54	354	8	297	7.0e-74	271	COG1533	DNA repair photolyase	297
637681799	206	35.51	32	137	15	121	2.0e-16	79.3	COG2863	Cytochrome c553	121
637681800	481	40.95	21	480	1	454	5.0e-118	418	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
637681801	269	39.78	7	268	4	263	1.0e-54	206	COG0388	Predicted amidohydrolase	274
637681802	1307	27.31	38	1290	3	1271	0.0e+00	588	COG3164	Uncharacterized conserved protein YhdP, contains DUF3971 and AsmA2 domains	1271
637681803	899	44.24	2	896	42	954	0.0e+00	821	COG1391	Glutamine synthetase adenylyltransferase	963
637681805	141	51.05	1	141	1	129	5.0e-35	139	COG1970	Large-conductance mechanosensitive channel	130
637681806	385	36.02	22	385	21	389	2.0e-87	316	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
637681807	362	49	16	355	10	342	1.0e-105	376	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
637681808	209	40.93	1	209	5	219	2.0e-49	189	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
637681809	316	33.33	5	310	1	291	2.0e-55	209	COG1230	Co/Zn/Cd efflux system component	296
637681810	247	22.6	45	246	29	229	1.0e-12	67.2	COG5581	c-di-GMP-binding flagellar brake protein YcgR, contains PilZNR and PilZ domains	233
637681811	284	46.5	1	282	1	286	4.0e-73	268	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
637681812	287	50.7	1	282	1	286	4.0e-72	264	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
637681815	1068	27.42	14	1064	3	1009	0.0e+00	623	COG0841	Multidrug efflux pump subunit AcrB	1009
637681816	333	28.32	2	323	13	356	5.0e-14	72.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
637681817	417	25.45	2	370	25	414	2.0e-20	93.7	COG2271	Sugar phosphate permease	448
637681818	100	44.09	9	100	14	106	9.0e-15	71.7	COG4654	Cytochrome c551/c552	110
637681819	352	30.48	129	337	3	210	2.0e-25	109	COG0569	Trk K+ transport system, NAD-binding component	225
637681822	923	34.86	178	501	21	335	5.0e-44	173	COG0642	Signal transduction histidine kinase	336
637681824	234	37.95	6	226	4	225	1.0e-46	180	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
637681826	637	29.35	215	392	1	181	9.0e-15	75.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
637681826	637	30.3	406	631	4	233	2.0e-34	140	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
637681827	487	25.98	1	446	1	421	3.0e-49	189	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
637681828	137	33.06	5	123	4	115	9.0e-14	69.2	COG4969	Tfp pilus assembly protein, major pilin PilA	125
637681829	528	23.69	185	509	5	309	1.0e-26	114	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
637681830	255	22.3	1	225	2	259	3.0e-20	92	COG1234	Ribonuclease BN, tRNA processing enzyme	292
637681832	274	37.36	7	266	8	262	1.0e-55	209	COG0631	Serine/threonine protein phosphatase PrpC	262
637681833	317	36.7	1	317	3	329	6.0e-61	227	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
637681834	233	26.23	5	228	11	253	6.0e-31	127	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
637681835	297	56.38	1	297	1	289	5.0e-103	367	COG0074	Succinyl-CoA synthetase, alpha subunit	293
637681836	386	55.15	1	386	1	385	0.0e+00	500	COG0045	Succinyl-CoA synthetase, beta subunit	387
637681837	452	28.73	5	452	9	451	6.0e-55	208	COG0534	Na+-driven multidrug efflux pump	455
637681838	431	57.48	7	431	14	437	0.0e+00	534	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
637681840	233	38.46	1	233	36	263	4.0e-56	211	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
637681841	598	19.55	11	522	10	569	5.0e-10	60.1	COG3170	Tfp pilus assembly protein FimV	755
637681842	248	43.43	1	248	1	250	1.0e-64	239	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
637681843	383	47.37	55	375	34	341	3.0e-72	265	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
637681844	268	51	1	251	1	244	1.0e-74	273	COG0121	Predicted glutamine amidotransferase	252
637681845	275	51.85	8	247	9	249	9.0e-56	210	COG0805	Sec-independent protein secretion pathway component TatC	255
637681846	120	35.11	1	94	1	94	8.0e-13	65.8	COG1826	Sec-independent protein translocase protein TatA	94
637681847	76	27.4	1	73	1	73	5.0e-13	66.1	COG1826	Sec-independent protein translocase protein TatA	94
637681848	116	45.19	2	105	1	104	1.0e-25	108	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
637681849	108	52.81	7	95	1	89	4.0e-24	103	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
637681850	132	56.6	8	112	5	110	6.0e-41	159	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
637681851	252	69.41	1	252	1	255	2.0e-113	401	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
637681852	246	51.03	1	243	2	240	4.0e-77	281	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
637681853	215	50.23	6	215	2	204	8.0e-74	270	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
637681854	195	62.05	1	195	3	195	2.0e-80	292	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
637681855	356	38.27	5	354	2	351	4.0e-84	304	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
637681857	172	28.57	1	172	5	179	8.0e-19	86.8	COG2059	Chromate transport protein ChrA	195
637681858	187	33.88	8	187	1	180	4.0e-25	107	COG2059	Chromate transport protein ChrA	195
637681859	433	54.29	4	433	1	423	0.0e+00	544	COG0141	Histidinol dehydrogenase	425
637681860	214	48.15	2	213	1	214	1.0e-56	212	COG0040	ATP phosphoribosyltransferase	290
637681861	426	41.32	45	424	1	379	3.0e-78	286	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
637681862	161	27.08	19	161	15	156	1.0e-12	65.7	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
637681863	339	35.78	1	338	1	332	8.0e-72	264	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
637681864	68	62.69	1	67	1	67	8.0e-25	105	COG1278	Cold shock protein, CspA family	67
637681865	417	61.96	1	416	1	418	0.0e+00	600	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
637681866	81	48.1	2	80	1	79	2.0e-19	87.3	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
637681867	250	18.87	25	236	45	247	5.0e-08	51.7	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
637681868	239	43.39	1	238	1	242	5.0e-67	247	COG1131	ABC-type multidrug transport system, ATPase component	293
637681870	204	39.3	1	195	2	202	9.0e-41	160	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
637681871	241	42.17	16	241	9	237	6.0e-62	230	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
637681873	263	46.33	4	262	8	265	1.0e-61	229	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
637681874	270	54.83	1	258	3	261	6.0e-100	357	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
637681875	494	40.72	30	488	7	451	3.0e-107	382	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
637681876	459	37.59	1	263	7	269	5.0e-44	172	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
637681877	594	22.87	35	561	5	551	2.0e-45	177	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
637681879	568	42.86	67	562	4	498	5.0e-129	455	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
637681880	399	34.17	1	398	2	397	1.0e-75	277	COG1459	Type II secretory pathway, component PulF	397
637681885	244	26.77	1	125	1	121	1.0e-07	50.4	COG2165	Type II secretory pathway, pseudopilin PulG	149
637681886	431	29.95	214	418	20	215	2.0e-29	124	COG2114	Adenylate cyclase, class 3	227
637681889	652	24.9	406	650	4	221	3.0e-17	84.1	COG0569	Trk K+ transport system, NAD-binding component	225
637681889	652	38.54	1	378	5	386	1.0e-59	225	COG0475	Kef-type K+ transport system, membrane component KefB	397
637681890	332	55.72	15	214	1	201	2.0e-65	242	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
637681891	175	52.98	5	172	3	170	3.0e-54	204	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
637681892	193	23.89	7	186	6	182	2.0e-19	89.2	COG3117	Lipopolysaccharide export system protein LptC	188
637681893	200	28.57	5	179	9	173	1.0e-20	93.1	COG1934	Lipopolysaccharide export system protein LptA	173
637681896	254	27.13	4	252	3	255	2.0e-48	185	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
637681898	1329	37.47	37	950	1	812	0.0e+00	675	COG1643	HrpA-like RNA helicase	845
637681899	327	32.92	8	315	2	286	1.0e-40	160	COG4974	Site-specific recombinase XerD	300
637681906	341	30.46	6	328	3	303	9.0e-37	147	COG3547	Transposase	303
637681908	194	40.43	1	186	10	197	1.0e-37	149	COG3548	Uncharacterized membrane protein	197
637681909	168	42.53	1	166	2	170	1.0e-35	142	COG3153	Predicted N-acetyltransferase YhbS	171
637681910	131	29.69	1	128	7	127	3.0e-18	83.8	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
637681911	143	23.24	6	139	8	149	2.0e-09	55.3	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
637681914	205	48.08	1	205	17	224	6.0e-45	174	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
637681915	206	32.76	2	58	1	58	3.0e-07	48.6	COG1278	Cold shock protein, CspA family	67
637681915	206	37.78	104	193	2	91	8.0e-17	80.7	COG3326	Uncharacterized membrane protein YsdA, DUF1294 family	94
637681916	274	20.66	16	241	47	283	2.0e-13	70	COG0657	Acetyl esterase/lipase	312
637681918	135	41.67	8	126	1	120	3.0e-16	77.5	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
637681919	601	31.03	53	576	7	472	1.0e-86	314	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
637681921	389	18.58	9	380	9	381	5.0e-12	65.5	COG0827	Adenine-specific DNA methylase	381
637681922	270	29.37	3	267	2	239	2.0e-32	132	COG0284	Orotidine-5'-phosphate decarboxylase	240
637681923	286	55.29	1	283	1	291	3.0e-99	355	COG2321	Predicted metalloprotease	295
637681925	271	31.14	51	271	42	267	1.0e-26	113	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
637681927	117	28.93	1	114	8	128	1.0e-22	98.1	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
637681930	365	47.15	2	364	7	360	1.0e-95	343	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
637681931	1055	31.52	212	559	1	336	1.0e-42	169	COG0642	Signal transduction histidine kinase	336
637681933	384	23.14	2	313	16	352	5.0e-21	95.8	COG1566	Multidrug resistance efflux pump	352
637681934	228	49.12	3	226	1	226	3.0e-73	268	COG1136	ABC-type lipoprotein export system, ATPase component	226
637681935	402	30.07	19	402	2	419	7.0e-32	131	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
637681938	399	31.03	18	399	1	419	6.0e-34	138	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
637681939	145	38.46	15	138	29	158	2.0e-20	92.1	COG2030	Acyl dehydratase	159
637681940	379	41.37	138	377	1	237	2.0e-56	213	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
637681942	103	58.25	1	103	1	103	7.0e-36	141	COG0261	Ribosomal protein L21	103
637681943	87	72.41	1	87	1	86	7.0e-32	128	COG0211	Ribosomal protein L27	87
637681944	363	54.72	1	359	1	353	0.0e+00	480	COG0536	GTPase involved in cell partioning and DNA repair	369
637681945	372	55.41	4	371	1	368	2.0e-126	445	COG0263	Glutamate 5-kinase	369
637681946	384	19.13	3	384	1	354	4.0e-14	72.7	COG3203	Outer membrane protein (porin)	354
637681947	262	54.26	5	262	1	254	2.0e-79	289	COG0134	Indole-3-glycerol phosphate synthase	254
637681948	340	53.55	1	338	2	338	1.0e-114	406	COG0547	Anthranilate phosphoribosyltransferase	338
637681949	190	64.17	1	186	3	189	4.0e-84	304	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
637681952	336	22.9	12	307	5	291	4.0e-20	92.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
637681953	491	54.74	18	487	1	462	0.0e+00	509	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
637681954	226	37.38	1	212	2	212	4.0e-43	168	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
637681955	233	54.82	6	233	4	220	9.0e-82	296	COG0036	Pentose-5-phosphate-3-epimerase	220
637681956	127	58.4	3	127	2	126	2.0e-46	178	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
637681958	375	25.07	3	355	8	352	1.0e-26	114	COG0628	Predicted PurR-regulated permease PerM	355
637681959	408	47.3	2	408	1	404	5.0e-130	458	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
637681960	904	59.71	2	897	1	822	0.0e+00	1086	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
637681964	305	62.41	1	289	1	290	5.0e-126	443	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
637681965	398	55.28	3	321	2	321	1.0e-89	324	COG0206	Cell division GTPase FtsZ	338
637681966	409	48.68	3	409	2	418	3.0e-129	455	COG0849	Cell division ATPase FtsA	418
637681967	246	30.08	1	242	21	259	2.0e-33	136	COG1589	Cell division septal protein FtsQ	269
637681968	301	47.15	3	298	1	316	4.0e-81	294	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
637681969	463	51.72	1	461	3	455	0.0e+00	545	COG0773	UDP-N-acetylmuramate-alanine ligase	459
637681970	352	45.4	3	352	1	356	5.0e-92	331	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
637681971	387	42.29	15	386	13	380	1.0e-75	277	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
637681972	450	44.47	3	449	5	447	5.0e-118	418	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
637681973	367	41.53	20	367	1	316	1.0e-56	213	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
637681974	456	45.78	1	446	1	448	1.0e-121	430	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
637681975	492	43.5	5	484	1	475	4.0e-116	412	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
637681976	582	36.5	16	569	5	599	3.0e-123	436	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
637681977	94	38.1	3	86	22	105	5.0e-15	72.6	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
637681978	308	53.04	1	308	1	312	7.0e-110	390	COG0275	16S rRNA C1402 N4-methylase RsmH	314
637681979	148	43.92	1	148	1	146	2.0e-34	138	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
637681981	233	18.41	1	233	8	243	2.0e-20	93	COG1651	Protein-disulfide isomerase	244
637681982	387	34.97	4	385	3	384	3.0e-63	236	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
637681984	99	49.46	1	93	2	94	3.0e-18	83.3	COG0776	Bacterial nucleoid DNA-binding protein	94
637681985	215	61.18	12	180	13	181	2.0e-63	235	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
637681986	146	40.13	1	146	6	155	2.0e-37	148	COG3043	Nitrate reductase cytochrome c-type subunit	155
637681987	837	31.26	2	837	1	764	0.0e+00	580	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
637681988	89	29.76	3	86	5	88	7.0e-10	55.7	COG3062	Cytoplasmic chaperone NapD for the signal peptide of periplasmic nitrate reductase NapAB	94
637681989	187	49.47	1	184	2	188	4.0e-64	237	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
637681990	521	71.92	1	520	1	520	0.0e+00	840	COG3634	Alkyl hydroperoxide reductase subunit AhpF	520
637681991	162	47.68	1	151	7	157	3.0e-48	184	COG1607	Acyl-CoA hydrolase	157
637681993	199	37.5	1	145	2	145	1.0e-26	113	COG3617	Prophage antirepressor	176
637681994	133	22.73	11	133	1	131	3.0e-06	44.7	COG3756	Uncharacterized conserved protein YdaU, DUF1376 family	153
637681995	184	41.21	4	182	2	198	2.0e-25	109	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
637681997	571	25.74	33	354	2	321	2.0e-32	134	COG0270	Site-specific DNA-cytosine methylase	328
637682000	445	51.02	1	441	1	436	0.0e+00	538	COG0621	tRNA A37 methylthiotransferase MiaB	437
637682001	340	49.7	13	338	3	334	5.0e-100	358	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
637682002	149	44.3	9	148	3	151	4.0e-39	153	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
637682003	282	51.64	3	274	12	285	4.0e-92	331	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
637682004	487	38.05	8	483	12	507	1.0e-86	313	COG0815	Apolipoprotein N-acyltransferase	518
637682005	182	53.61	9	173	9	174	4.0e-62	230	COG0225	Peptide methionine sulfoxide reductase MsrA	174
637682007	327	73.49	20	313	1	298	0.0e+00	545	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
637682008	712	46.63	1	711	1	690	0.0e+00	710	COG0751	Glycyl-tRNA synthetase, beta subunit	691
637682009	183	40.56	1	180	3	179	8.0e-46	176	COG0241	Histidinol phosphatase or a related phosphatase	181
637682010	250	28.16	4	246	1	235	1.0e-26	113	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
637682011	239	32.02	10	236	2	220	2.0e-35	142	COG1451	Predicted metal-dependent hydrolase	223
637682012	127	25.36	1	125	1	138	4.0e-13	67.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
637682013	377	25.77	23	374	1	357	5.0e-51	195	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637682016	373	29.17	5	373	3	379	1.0e-35	144	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
637682017	138	55.08	18	135	1	118	7.0e-33	132	COG0818	Diacylglycerol kinase	123
637682020	393	28.83	1	380	1	379	6.0e-42	165	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
637682021	267	37.19	7	245	1	237	7.0e-59	220	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
637682022	982	37.5	553	831	59	327	3.0e-41	164	COG0642	Signal transduction histidine kinase	336
637682024	547	27.64	8	449	1	428	9.0e-35	142	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
637682025	399	66.41	1	395	2	391	0.0e+00	574	COG0027	Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	394
637682026	384	44.89	1	366	5	360	6.0e-103	367	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
637682028	454	41.34	16	192	1	179	2.0e-33	136	COG2059	Chromate transport protein ChrA	195
637682029	626	55.84	2	626	7	627	0.0e+00	770	COG3158	K+ transporter	627
637682030	230	43.61	7	230	2	227	9.0e-59	220	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
637682033	232	52.17	11	232	1	226	1.0e-72	266	COG0120	Ribose 5-phosphate isomerase	227
637682035	333	34.5	5	297	11	318	3.0e-54	205	COG0226	ABC-type phosphate transport system, periplasmic component	318
637682036	311	39.42	9	311	1	310	6.0e-63	234	COG0573	ABC-type phosphate transport system, permease component	310
637682037	312	39.2	12	308	6	290	3.0e-57	215	COG0581	ABC-type phosphate transport system, permease component	292
637682038	259	67.6	10	259	7	253	8.0e-121	426	COG1117	ABC-type phosphate transport system, ATPase component	253
637682039	229	39.29	1	224	3	225	4.0e-40	157	COG0704	Phosphate uptake regulator	240
637682040	228	48.25	3	226	1	226	3.0e-61	228	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
637682041	430	29	84	429	97	453	9.0e-45	174	COG5002	Signal transduction histidine kinase	459
637682043	431	33.33	252	430	21	206	5.0e-11	62.6	COG0666	Ankyrin repeat	235
637682044	611	33.05	11	243	7	241	1.0e-45	178	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
637682046	149	22.07	1	142	1	137	1.0e-05	42.2	COG3153	Predicted N-acetyltransferase YhbS	171
637682048	220	32.99	4	193	3	196	2.0e-30	126	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
637682049	611	34.95	235	606	9	378	2.0e-57	217	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
637682050	335	26.32	1	299	2	303	4.0e-40	158	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
637682052	554	28.84	178	554	34	408	3.0e-34	140	COG0840	Methyl-accepting chemotaxis protein	408
637682053	294	25.42	5	294	1	293	3.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
637682054	405	22.16	36	393	37	386	1.0e-12	68.3	COG2814	Predicted arabinose efflux permease, MFS family	394
637682055	143	30.37	5	139	4	137	9.0e-22	96.3	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
637682056	90	58.89	1	90	1	90	8.0e-34	135	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
637682057	439	39.26	25	290	1	265	1.0e-60	227	COG0548	Acetylglutamate kinase	265
637682057	439	50.69	294	435	1	144	1.0e-38	154	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
637682058	501	42.29	244	494	19	270	2.0e-74	274	COG2326	Polyphosphate kinase 2, PPK2 family	270
637682059	245	44.94	1	241	1	246	4.0e-57	214	COG1385	16S rRNA U1498 N3-methylase RsmE	246
637682062	338	52.55	5	337	2	323	1.0e-120	426	COG0158	Fructose-1,6-bisphosphatase	326
637682064	668	61.27	12	668	9	663	0.0e+00	995	COG0021	Transketolase	663
637682065	342	58.33	2	336	1	328	9.0e-122	429	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
637682066	349	41.79	10	341	1	329	4.0e-100	358	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
637682067	393	52.61	1	393	2	395	0.0e+00	470	COG0126	3-phosphoglycerate kinase	395
637682068	477	51.58	1	471	3	477	0.0e+00	557	COG0469	Pyruvate kinase	477
637682069	354	46.67	1	329	1	286	2.0e-96	345	COG0191	Fructose/tagatose bisphosphate aldolase	286
637682070	193	29.87	45	193	35	188	9.0e-21	93.4	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
637682072	1211	39.78	716	1162	29	465	3.0e-64	241	COG2319	WD40 repeat	466
637682080	148	27.12	16	131	1	114	6.0e-12	63.4	COG3628	Phage baseplate assembly protein W	116
637682081	92	40.23	6	92	16	97	6.0e-07	45.7	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
637682082	574	22.54	129	514	118	523	6.0e-28	119	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
637682094	413	41.44	202	380	1	180	3.0e-44	172	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
637682095	170	50.39	8	136	11	136	2.0e-30	125	COG4628	Uncharacterized conserved protein, DUF2132 family	136
637682096	583	24.57	163	393	7	232	2.0e-11	64.2	COG2202	PAS domain	232
637682096	583	45.08	381	572	1	178	6.0e-42	166	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
637682097	345	44.85	1	329	1	286	1.0e-96	346	COG0191	Fructose/tagatose bisphosphate aldolase	286
637682098	339	57.69	2	337	1	334	1.0e-123	436	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
637682099	690	56.78	6	680	1	662	0.0e+00	960	COG0021	Transketolase	663
637682100	290	57.24	1	290	1	289	5.0e-117	414	COG3954	Phosphoribulokinase	289
637682101	357	53.17	5	332	1	325	3.0e-118	418	COG0158	Fructose-1,6-bisphosphatase	326
637682102	233	29.52	4	230	2	212	3.0e-26	112	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
637682105	204	44.5	4	201	5	203	4.0e-37	148	COG2860	Uncharacterized membrane protein YeiH	209
637682110	459	34.89	24	440	22	423	6.0e-64	238	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
637682111	316	36.88	7	304	1	297	2.0e-40	159	COG0583	DNA-binding transcriptional regulator, LysR family	297
637682112	443	37.47	19	434	11	417	4.0e-78	285	COG4949	Uncharacterized membrane-anchored protein	424
637682113	310	31.89	10	307	1	247	2.0e-58	219	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
637682118	257	32.41	15	257	30	281	4.0e-29	121	COG5473	Uncharacterized membrane protein	290
637682119	684	54.82	1	681	6	681	0.0e+00	851	COG0339	Zn-dependent oligopeptidase	683
637682121	254	49.42	1	253	1	259	3.0e-88	318	COG0708	Exonuclease III	261
637682122	222	27.96	15	214	6	214	8.0e-22	97.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
637682125	192	41.03	1	184	1	194	1.0e-28	119	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
637682126	487	12.79	136	428	1	287	2.0e-09	57.4	COG4916	Uncharacterized protein	329
637682127	340	20.24	97	337	48	291	2.0e-10	59.8	COG4974	Site-specific recombinase XerD	300
637682129	255	49	6	254	4	254	6.0e-83	300	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
637682130	329	55.42	1	327	2	329	1.0e-109	389	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
637682131	438	21.01	18	287	7	266	1.0e-12	67.8	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
637682132	849	29.24	99	845	52	784	3.0e-110	393	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
637682133	341	44.15	1	334	9	346	6.0e-88	318	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
637682135	432	33.42	27	426	18	384	7.0e-69	255	COG0006	Xaa-Pro aminopeptidase	384
637682136	381	33.33	7	375	1	384	9.0e-55	208	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
637682137	290	36.58	1	290	5	299	1.0e-53	203	COG1575	1,4-dihydroxy-2-naphthoate octaprenyltransferase	303
637682138	337	45.68	1	322	2	322	1.0e-92	333	COG0042	tRNA-dihydrouridine synthase	323
637682139	77	50	2	77	23	98	2.0e-20	90.8	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
637682140	530	61.39	3	530	2	515	0.0e+00	731	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
637682141	425	60.28	1	425	1	425	0.0e+00	614	COG0151	Phosphoribosylamine-glycine ligase	428
637682142	298	64.88	1	297	5	302	6.0e-128	450	COG0408	Coproporphyrinogen III oxidase	303
637682144	394	31.22	1	391	1	390	9.0e-53	201	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
637682145	348	29.14	4	345	9	358	7.0e-43	167	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
637682146	260	36.07	9	251	1	238	4.0e-38	152	COG1587	Uroporphyrinogen-III synthase	248
637682147	311	56.77	6	307	3	305	1.0e-108	386	COG0181	Porphobilinogen deaminase	307
637682149	868	36.79	1	860	4	859	0.0e+00	633	COG0308	Aminopeptidase N	859
637682150	163	25.35	34	163	6	144	4.0e-06	44.2	COG0328	Ribonuclease HI	154
637682151	127	25.37	49	112	1	67	1.0e-07	48.4	COG0695	Glutaredoxin	80
637682152	262	36.9	11	258	2	240	3.0e-39	155	COG3279	DNA-binding response regulator, LytR/AlgR family	244
637682154	462	60.26	10	462	6	458	0.0e+00	643	COG0165	Argininosuccinate lyase	459
637682156	106	62.86	1	105	1	105	5.0e-43	165	COG0278	Glutaredoxin-related protein	105
637682157	270	45.99	1	266	1	272	2.0e-66	245	COG2890	Methylase of polypeptide chain release factors	280
637682158	285	25.09	26	277	31	297	2.0e-33	136	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
637682159	620	33.53	131	469	21	327	8.0e-40	158	COG0642	Signal transduction histidine kinase	336
637682160	360	65.01	1	359	1	363	0.0e+00	537	COG0216	Protein chain release factor A	363
637682162	416	48.79	1	412	2	411	7.0e-128	450	COG0373	Glutamyl-tRNA reductase	414
637682163	355	59.66	1	341	1	345	2.0e-118	418	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
637682164	287	71	6	274	12	280	1.0e-108	386	COG4208	ABC-type sulfate transport system, permease component	287
637682165	291	55.88	1	272	1	272	6.0e-73	267	COG0555	ABC-type sulfate transport system, permease component	274
637682166	332	57.59	16	330	30	345	2.0e-119	422	COG1613	ABC-type sulfate transport system, periplasmic component	348
637682167	188	25.67	1	187	7	190	3.0e-26	111	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
637682169	142	36.03	1	133	1	132	5.0e-16	76.9	COG2703	Hemerythrin	144
637682173	320	43.34	2	320	21	343	2.0e-84	306	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
637682174	337	50.77	3	317	1	322	2.0e-104	372	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
637682176	400	34.45	5	397	1	406	5.0e-78	285	COG0004	Ammonia channel protein AmtB	409
637682177	405	36.24	55	404	7	370	5.0e-77	281	COG2821	Membrane-bound lytic murein transglycosylase	373
637682178	296	55.48	7	289	6	282	9.0e-103	366	COG2607	Predicted ATPase, AAA+ superfamily	287
637682179	314	29.63	7	109	11	113	8.0e-08	51.6	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
637682179	314	34.94	151	313	23	188	4.0e-34	138	COG0352	Thiamine monophosphate synthase	211
637682180	65	46.43	5	60	7	62	2.0e-10	57.8	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
637682181	252	32.4	1	250	1	244	5.0e-61	227	COG4582	Cell division protein ZapD, interacts with FtsZ	244
637682182	207	39.3	3	203	2	201	2.0e-46	178	COG0237	Dephospho-CoA kinase	201
637682184	454	59.12	5	435	3	432	0.0e+00	609	COG1350	Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB)	432
637682186	404	35.07	8	404	29	409	7.0e-73	267	COG3876	Uncharacterized conserved protein YbbC, DUF1343 family	409
637682187	1028	34.69	608	877	67	326	6.0e-42	166	COG0642	Signal transduction histidine kinase	336
637682187	1028	38.58	904	1028	1	125	4.0e-20	94.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
637682189	299	32.66	3	298	1	294	5.0e-44	171	COG2177	Cell division protein FtsX	297
637682190	217	53.7	1	216	1	216	5.0e-72	263	COG2884	ABC-type ATPase involved in cell division	223
637682191	361	53.56	48	361	18	340	5.0e-107	381	COG0552	Signal recognition particle GTPase	340
637682192	452	33.56	8	444	2	438	4.0e-81	295	COG0612	Predicted Zn-dependent peptidase	438
637682194	429	28.19	22	426	16	428	4.0e-65	242	COG0612	Predicted Zn-dependent peptidase	438
637682195	184	43.32	3	179	1	187	6.0e-51	193	COG0742	16S rRNA G966 N2-methylase RsmD	187
637682196	164	58.97	5	160	1	156	1.0e-59	222	COG0669	Phosphopantetheine adenylyltransferase	159
637682199	277	48.03	1	277	1	273	5.0e-86	311	COG0266	Formamidopyrimidine-DNA glycosylase	273
637682201	190	30.24	1	186	5	203	1.0e-20	93.1	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
637682202	274	45.42	2	273	6	289	2.0e-82	298	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
637682204	316	58.79	4	314	3	313	1.0e-118	419	COG0462	Phosphoribosylpyrophosphate synthetase	314
637682205	203	47.31	3	95	2	93	2.0e-22	99.2	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
637682206	192	50.26	3	191	1	190	2.0e-67	248	COG0193	Peptidyl-tRNA hydrolase	190
637682207	363	62.37	1	363	1	372	0.0e+00	502	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
637682209	499	51.2	2	495	9	508	0.0e+00	542	COG4262	Predicted spermidine synthase with an N-terminal membrane domain	508
637682210	218	39.34	35	215	6	188	4.0e-43	168	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
637682211	369	34.29	208	369	1	174	2.0e-28	120	COG0807	GTP cyclohydrolase II	193
637682211	369	59.7	7	207	3	202	1.0e-76	280	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
637682212	160	45.33	12	157	3	152	5.0e-43	166	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
637682213	163	44.3	15	156	3	151	7.0e-32	130	COG0781	Transcription termination factor NusB	151
637682214	325	45.68	1	321	2	317	4.0e-83	301	COG0611	Thiamine monophosphate kinase	317
637682215	161	38.06	4	156	6	159	7.0e-26	110	COG1267	Phosphatidylglycerophosphatase A	160
637682218	718	28.64	1	210	9	216	7.0e-28	119	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
637682222	166	35.67	10	162	41	197	1.0e-22	99.3	COG0791	Cell wall-associated hydrolase, NlpC family	197
637682223	484	49.68	13	481	3	468	0.0e+00	522	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
637682224	223	32.37	18	222	23	262	1.0e-37	149	COG4278	Uncharacterized protein	269
637682225	721	26.35	38	349	1	327	5.0e-25	109	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
637682227	337	39.3	1	337	1	341	4.0e-84	305	COG4260	Membrane protease subunit, stomatin/prohibitin family, contains C-terminal Zn-ribbon domain	345
637682228	133	42.64	5	133	4	132	1.0e-20	92.2	COG3766	Uncharacterized membrane protein YjfL, UPF0719 family	133
637682229	561	39.76	308	561	2	254	3.0e-63	236	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
637682230	435	31.64	114	388	72	344	7.0e-50	191	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
637682231	238	27.38	1	235	1	248	9.0e-33	133	COG1521	Pantothenate kinase type III	251
637682232	267	41.91	25	260	1	236	2.0e-47	182	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
637682233	476	48.83	5	469	2	458	0.0e+00	502	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
637682234	356	46.67	2	355	1	356	8.0e-93	334	COG3852	Signal transduction histidine kinase, nitrogen specific	363
637682235	362	31.35	1	357	3	372	2.0e-26	113	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
637682236	1047	30.1	6	1042	1	1008	0.0e+00	803	COG0841	Multidrug efflux pump subunit AcrB	1009
637682238	471	52.31	3	471	2	443	0.0e+00	532	COG0174	Glutamine synthetase	443
637682239	389	40.55	11	301	3	292	9.0e-68	250	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
637682240	150	24.79	30	150	10	109	2.0e-09	55.3	COG0607	Rhodanese-related sulfurtransferase	110
637682241	365	35.81	3	365	7	323	2.0e-85	309	COG0379	Quinolinate synthase	324
637682242	252	33.98	1	247	5	255	9.0e-44	170	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
637682243	397	32.72	1	370	52	432	4.0e-54	205	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
637682247	405	27.99	1	285	1	286	4.0e-22	99.6	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
637682249	173	29.51	31	149	8	127	6.0e-12	64.2	COG0526	Thiol-disulfide isomerase or thioredoxin	127
637682250	358	51.66	1	357	4	348	6.0e-117	414	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
637682253	796	19.97	17	781	6	725	1.0e-61	231	COG1033	Predicted exporter protein, RND superfamily	727
637682255	63	37.5	1	63	1	64	2.0e-11	60.3	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
637682256	262	41	3	262	2	262	1.0e-60	226	COG3971	2-keto-4-pentenoate hydratase	264
637682257	343	22.62	6	330	1	334	2.0e-43	169	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
637682258	304	54.55	1	294	1	305	2.0e-96	345	COG4569	Acetaldehyde dehydrogenase (acetylating)	310
637682259	264	34.59	3	260	1	251	2.0e-34	139	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
637682260	260	44.06	1	260	2	262	4.0e-66	244	COG3971	2-keto-4-pentenoate hydratase	264
637682261	274	30.71	12	274	5	281	2.0e-25	109	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
637682262	484	43.45	6	484	3	469	0.0e+00	460	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
637682263	142	40.88	6	141	4	139	2.0e-21	94.6	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
637682264	308	20.34	2	215	4	226	3.0e-07	49.5	COG2514	Catechol-2,3-dioxygenase	265
637682265	235	31.53	11	231	12	228	2.0e-25	109	COG1802	DNA-binding transcriptional regulator, GntR family	230
637682266	112	27.66	1	91	3	95	2.0e-06	44.7	COG0633	Ferredoxin	102
637682267	353	27.73	12	335	47	408	1.0e-41	164	COG2871	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF	410
637682274	300	33	1	299	1	297	8.0e-33	134	COG0583	DNA-binding transcriptional regulator, LysR family	297
637682278	266	63.14	1	255	1	255	1.0e-93	336	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
637682279	311	18.05	14	268	16	263	5.0e-06	45.7	COG2514	Catechol-2,3-dioxygenase	265
637682280	489	41.82	9	489	3	469	6.0e-126	444	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
637682281	305	54.58	2	293	3	305	7.0e-95	340	COG4569	Acetaldehyde dehydrogenase (acetylating)	310
637682282	354	23.88	9	333	1	334	5.0e-47	182	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
637682284	144	37.31	72	137	1	67	4.0e-07	47.6	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
637682285	532	27.9	169	530	50	408	9.0e-40	158	COG0840	Methyl-accepting chemotaxis protein	408
637682286	208	55.03	10	198	5	193	3.0e-59	221	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
637682288	464	23.83	2	434	1	408	6.0e-33	135	COG2067	Long-chain fatty acid transport protein	440
637682289	338	27.37	6	97	8	102	1.0e-06	47.4	COG0633	Ferredoxin	102
637682289	338	32.13	113	332	16	221	9.0e-31	127	COG0543	NAD(P)H-flavin reductase	252
637682292	111	32.69	1	102	3	106	8.0e-16	75.8	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
637682295	759	29.62	249	615	1	335	1.0e-39	158	COG0642	Signal transduction histidine kinase	336
637682296	429	27.27	13	288	40	310	1.0e-18	88.3	COG3344	Retron-type reverse transcriptase	328
637682298	493	35.15	19	180	1	161	3.0e-26	113	COG3666	Transposase	161
637682300	389	32.16	123	388	5	283	3.0e-36	146	COG1408	Predicted phosphohydrolase, MPP superfamily	284
637682301	504	38.63	37	500	1	448	5.0e-53	202	COG1538	Outer membrane protein TolC	457
637682302	1062	47.65	2	1039	1	1009	0.0e+00	1005	COG0841	Multidrug efflux pump subunit AcrB	1009
637682303	387	34.77	5	370	1	365	6.0e-29	122	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
637682304	290	44.56	1	278	27	311	4.0e-40	158	COG0657	Acetyl esterase/lipase	312
637682305	335	32.56	3	298	2	295	4.0e-41	162	COG0583	DNA-binding transcriptional regulator, LysR family	297
637682306	184	22.1	4	179	4	176	9.0e-16	76.8	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
637682307	343	38.48	13	338	1	326	2.0e-57	216	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
637682308	295	28.67	12	294	1	293	2.0e-32	132	COG0583	DNA-binding transcriptional regulator, LysR family	297
637682309	303	25.17	8	295	2	282	3.0e-21	95.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
637682310	736	74.83	6	736	17	730	0.0e+00	1187	COG0376	Catalase (peroxidase I)	730
637682311	286	39.02	3	286	56	334	2.0e-67	249	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
637682315	253	41.9	1	250	2	254	2.0e-64	238	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
637682316	418	27.63	1	417	5	377	7.0e-39	155	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
637682317	717	45.49	21	711	13	700	0.0e+00	816	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
637682318	68	50.75	1	65	1	67	2.0e-14	71.1	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
637682319	202	55.56	3	182	4	182	6.0e-72	263	COG0194	Guanylate kinase	191
637682320	860	40	447	705	81	326	4.0e-40	160	COG0642	Signal transduction histidine kinase	336
637682322	288	42.07	1	288	1	290	7.0e-71	260	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
637682323	314	24.51	17	296	1	286	2.0e-27	116	COG0515	Serine/threonine protein kinase	384
637682324	306	34.94	1	244	6	252	2.0e-43	169	COG0631	Serine/threonine protein phosphatase PrpC	262
637682325	238	59.24	1	237	8	230	1.0e-77	282	COG0689	Ribonuclease PH	230
637682326	195	51.53	1	195	1	193	4.0e-63	234	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
637682327	399	46.19	27	399	34	410	5.0e-109	388	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
637682328	221	38.83	27	214	3	185	1.0e-30	126	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
637682329	136	40.16	1	122	20	135	7.0e-16	76.2	COG3753	Uncharacterized conserved protein YidB, DUF937 family	143
637682330	559	42.83	1	542	3	530	0.0e+00	529	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
637682331	129	49.22	4	127	2	129	2.0e-39	154	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
637682332	304	42.38	1	299	1	299	2.0e-85	309	COG2974	DNA recombination-dependent growth factor C	303
637682334	246	47.3	27	243	4	225	8.0e-66	243	COG0220	tRNA G46 methylase TrmB	227
637682335	260	58.59	4	259	8	260	1.0e-97	349	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
637682336	67	44.78	1	67	2	68	1.0e-12	65.2	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
637682337	260	28.74	4	254	8	262	1.0e-34	140	COG0300	Short-chain dehydrogenase	265
637682340	587	38.73	3	587	1	577	0.0e+00	530	COG0018	Arginyl-tRNA synthetase	577
637682341	176	33.53	9	171	1	165	3.0e-21	94.6	COG3663	G:T/U-mismatch repair DNA glycosylase	169
637682343	506	47.13	5	501	9	509	0.0e+00	490	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
637682347	380	24.34	9	374	17	376	9.0e-15	75	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
637682348	166	53.46	1	159	3	160	1.0e-48	186	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
637682349	201	44.39	15	200	4	187	1.0e-44	173	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
637682351	147	40.91	36	142	13	121	1.0e-17	82	COG3245	Cytochrome c5	126
637682353	663	43.95	2	640	1	652	0.0e+00	575	COG0210	Superfamily I DNA or RNA helicase	655
637682356	378	66.13	4	378	1	374	0.0e+00	578	COG5008	Tfp pilus assembly protein, ATPase PilU	375
637682357	347	66.09	1	345	3	347	0.0e+00	548	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
637682358	229	56.33	2	228	1	228	3.0e-81	294	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
637682359	270	45.86	1	265	2	265	4.0e-64	238	COG0345	Pyrroline-5-carboxylate reductase	266
637682361	97	44.16	13	87	13	89	9.0e-18	81.9	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
637682363	415	35.29	1	415	1	422	9.0e-91	327	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
637682364	319	48.6	6	318	1	312	4.0e-99	354	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
637682365	169	44.1	8	158	6	158	6.0e-39	153	COG2065	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	179
637682366	146	44.2	1	137	1	138	2.0e-38	151	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
637682367	186	52.13	1	186	8	194	2.0e-55	208	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
637682368	470	44.99	7	467	5	461	3.0e-127	449	COG0415	Deoxyribodipyrimidine photolyase	461
637682369	1866	30.54	1115	1716	83	709	2.0e-99	358	COG0643	Chemotaxis protein histidine kinase CheA	716
637682370	706	35.95	376	705	81	408	4.0e-40	160	COG0840	Methyl-accepting chemotaxis protein	408
637682371	170	23.61	24	165	14	157	3.0e-10	58.4	COG0835	Chemotaxis signal transduction protein	165
637682374	291	40.53	10	272	2	263	1.0e-67	250	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
637682375	211	41.55	4	208	3	208	5.0e-39	154	COG0352	Thiamine monophosphate synthase	211
637682376	427	59.02	2	427	4	430	0.0e+00	582	COG0001	Glutamate-1-semialdehyde aminotransferase	432
637682377	112	51.46	6	108	3	105	1.0e-23	101	COG2076	Multidrug transporter EmrE and related cation transporters	106
637682378	736	28.72	12	569	23	545	8.0e-75	275	COG0659	Sulfate permease or related transporter, MFS superfamily	554
637682379	461	25.78	118	434	3	317	5.0e-43	168	COG0598	Mg2+ and Co2+ transporter CorA	322
637682381	274	38.13	1	272	5	281	7.0e-67	247	COG0169	Shikimate 5-dehydrogenase	283
637682382	296	18.41	88	288	66	244	1.0e-07	50.5	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
637682383	637	21.23	32	557	33	571	3.0e-45	177	COG0557	Exoribonuclease R	706
637682384	189	36.36	6	189	2	188	4.0e-44	170	COG3150	Predicted esterase YcpF, UPF0227 family	191
637682385	274	52.03	1	267	1	270	2.0e-70	259	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
637682389	301	34.67	3	275	2	268	1.0e-27	117	COG0583	DNA-binding transcriptional regulator, LysR family	297
637682390	402	29.59	18	402	2	419	1.0e-36	147	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
637682391	232	54.46	5	227	1	224	6.0e-81	293	COG1136	ABC-type lipoprotein export system, ATPase component	226
637682393	489	36.22	50	485	13	450	2.0e-49	190	COG1538	Outer membrane protein TolC	457
637682395	638	64.48	136	606	1	432	0.0e+00	748	COG0422	Thiamine biosynthesis protein ThiC	432
637682396	481	52.19	253	477	20	246	3.0e-70	259	COG3338	Carbonic anhydrase	250
637682397	214	26.29	6	180	4	178	6.0e-15	74.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
637682398	217	44.33	6	208	1	203	2.0e-57	215	COG2518	Protein-L-isoaspartate O-methyltransferase	209
637682399	107	34.55	1	107	1	110	6.0e-18	82.3	COG0607	Rhodanese-related sulfurtransferase	110
637682400	441	27.78	4	433	27	455	1.0e-43	171	COG1538	Outer membrane protein TolC	457
637682401	419	46.39	2	411	1	416	1.0e-128	453	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
637682402	317	32.71	1	314	2	314	5.0e-54	204	COG0859	ADP-heptose:LPS heptosyltransferase	334
637682404	335	31.69	1	334	1	313	3.0e-54	205	COG0451	Nucleoside-diphosphate-sugar epimerase	314
637682405	607	52.46	1	607	1	597	0.0e+00	767	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
637682408	250	38.89	14	250	34	285	9.0e-47	180	COG3176	Putative hemolysin	292
637682409	310	27.11	38	305	28	311	2.0e-34	139	COG0524	Sugar or nucleoside kinase, ribokinase family	311
637682411	296	47.04	1	296	2	300	2.0e-79	289	COG2264	Ribosomal protein L11 methylase PrmA	300
637682412	452	64.44	1	448	1	449	0.0e+00	624	COG0439	Biotin carboxylase	449
637682413	162	47.95	18	161	1	138	1.0e-26	112	COG0511	Biotin carboxyl carrier protein	140
637682414	141	64.75	1	139	6	143	7.0e-56	209	COG0757	3-dehydroquinate dehydratase	146
637682416	448	39.18	2	448	9	459	8.0e-129	453	COG0773	UDP-N-acetylmuramate-alanine ligase	459
637682417	758	42.81	430	755	2	323	3.0e-95	343	COG0280	Phosphotransacetylase	327
637682417	758	55.53	1	431	13	431	0.0e+00	560	COG0281	Malic enzyme	432
637682418	689	18.53	13	689	39	768	4.0e-17	83.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
637682421	154	42.11	1	133	4	136	4.0e-33	133	COG0864	Metal-responsive transcriptional regulator, contains CopG/Arc/MetJ DNA-binding domain	136
637682422	109	44.33	8	103	15	110	1.0e-20	91.5	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
637682428	667	38.25	344	525	1	181	4.0e-39	156	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
637682429	384	30.55	16	358	14	347	6.0e-36	145	COG3177	Fic family protein	348
637682432	386	45.4	63	386	8	318	3.0e-84	305	COG2826	Transposase and inactivated derivatives, IS30 family	318
637682433	472	28.94	1	472	1	530	4.0e-88	318	COG0374	Ni,Fe-hydrogenase I large subunit	545
637682434	333	31	1	315	49	355	9.0e-52	197	COG1740	Ni,Fe-hydrogenase I small subunit	355
637682435	495	44.77	16	492	7	457	9.0e-119	420	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
637682436	558	23.14	279	517	1	239	4.0e-17	83.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
637682436	558	23.91	1	256	2	294	2.0e-29	124	COG0223	Methionyl-tRNA formyltransferase	307
637682438	330	45.72	1	330	5	339	9.0e-93	333	COG0309	Hydrogenase maturation factor	339
637682439	374	54.18	1	370	1	362	0.0e+00	488	COG0409	Hydrogenase maturation factor	364
637682440	81	51.35	1	72	1	74	3.0e-16	76.8	COG0298	Hydrogenase maturation factor	82
637682442	96	29.27	1	81	1	78	6.0e-06	42.6	COG0298	Hydrogenase maturation factor	82
637682443	159	38.99	1	157	2	160	1.0e-25	109	COG0680	Ni,Fe-hydrogenase maturation factor	160
637682444	570	52.2	3	567	2	542	0.0e+00	625	COG0374	Ni,Fe-hydrogenase I large subunit	545
637682445	386	35.82	5	380	3	386	2.0e-49	190	COG5557	Ni/Fe-hydrogenase 2 integral membrane subunit HybB	401
637682446	351	31.48	32	247	3	199	4.0e-40	159	COG0437	Fe-S-cluster-containing dehydrogenase component	203
637682447	394	48.88	21	377	10	354	4.0e-109	388	COG1740	Ni,Fe-hydrogenase I small subunit	355
637682448	523	52.22	344	522	3	181	3.0e-48	186	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
637682449	260	20.37	47	256	59	270	9.0e-09	54.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
637682450	763	45.12	4	753	1	742	0.0e+00	727	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
637682451	352	41.06	122	324	1	200	2.0e-59	223	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
637682452	113	47.79	1	113	1	113	6.0e-28	116	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
637682455	66	50	15	66	3	54	3.0e-10	56.8	COG1773	Rubredoxin	55
637682459	204	33.76	3	159	1	157	9.0e-29	120	COG0680	Ni,Fe-hydrogenase maturation factor	160
637682460	234	52.25	16	233	7	227	2.0e-57	215	COG1969	Ni,Fe-hydrogenase I cytochrome b subunit	227
637682461	598	57.61	15	598	1	545	0.0e+00	707	COG0374	Ni,Fe-hydrogenase I large subunit	545
637682462	363	58.24	3	353	2	353	0.0e+00	511	COG1740	Ni,Fe-hydrogenase I small subunit	355
637682464	204	50	1	204	2	204	2.0e-59	221	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
637682465	222	53.85	2	222	1	221	4.0e-42	164	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
637682466	248	39.41	10	243	41	276	9.0e-32	130	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
637682467	66	32.81	3	66	2	65	1.0e-08	51.8	COG3114	Heme exporter protein D	67
637682468	153	47.68	2	152	3	153	1.0e-42	165	COG2332	Cytochrome c-type biogenesis protein CcmE	153
637682469	664	56.34	1	653	1	648	0.0e+00	656	COG1138	Cytochrome c biogenesis factor	648
637682470	194	23.81	29	172	3	127	5.0e-07	47.6	COG0526	Thiol-disulfide isomerase or thioredoxin	127
637682471	162	47.44	4	159	2	153	4.0e-39	154	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
637682472	279	32.35	4	272	3	271	5.0e-38	151	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
637682476	667	54.12	1	667	1	644	0.0e+00	819	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
637682477	511	59.42	1	511	11	526	0.0e+00	710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
637682478	329	49.84	11	329	5	323	9.0e-99	353	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
637682479	716	55.22	583	716	9	142	4.0e-42	166	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
637682479	716	59.16	12	551	3	547	0.0e+00	707	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
637682480	233	40.89	10	233	6	229	6.0e-37	147	COG1802	DNA-binding transcriptional regulator, GntR family	230
637682483	557	47.56	32	548	1	528	0.0e+00	463	COG4147	Na+(or H+)/acetate symporter ActP	529
637682484	106	43.56	1	101	1	100	3.0e-19	86.8	COG3162	Uncharacterized membrane protein, DUF485 family	102
637682485	258	40.54	1	255	4	257	7.0e-42	164	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
637682486	269	31.02	1	268	1	256	5.0e-09	55	COG0730	Uncharacterized membrane protein YfcA	258
637682487	304	26.56	1	294	2	305	2.0e-32	133	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
637682488	297	40	25	294	7	284	2.0e-39	155	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
637682494	450	30.53	52	444	1	377	1.0e-64	241	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
637682495	183	26.75	25	181	5	158	6.0e-15	74.2	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
637682496	341	25.99	5	327	1	315	6.0e-39	155	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
637682497	239	34.38	12	234	5	227	6.0e-37	147	COG1802	DNA-binding transcriptional regulator, GntR family	230
637682498	266	30.77	1	266	3	256	1.0e-10	60.8	COG0730	Uncharacterized membrane protein YfcA	258
637682499	153	61.22	1	146	2	147	5.0e-54	203	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
637682500	111	29.76	8	89	4	87	1.0e-11	61.5	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
637682502	719	23.31	12	719	13	699	6.0e-51	196	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
637682503	713	25.08	63	712	6	608	7.0e-49	189	COG4206	Outer membrane cobalamin receptor protein	608
637682504	325	44.88	4	325	1	331	2.0e-50	192	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
637682505	257	44.49	4	248	1	245	7.0e-62	230	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
637682506	196	50.52	4	196	5	198	3.0e-62	231	COG2109	ATP:corrinoid adenosyltransferase	198
637682507	427	43.11	5	427	1	450	6.0e-122	431	COG1797	Cobyrinic acid a,c-diamide synthase	451
637682508	288	25.87	34	288	1	281	4.0e-22	98.9	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
637682509	659	37.14	229	503	68	334	1.0e-42	168	COG0642	Signal transduction histidine kinase	336
637682510	499	45.81	14	499	10	488	0.0e+00	558	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
637682511	337	20.76	48	278	4	226	1.0e-12	68	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
637682513	367	22.65	10	181	18	198	2.0e-06	47	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
637682514	225	53.54	1	224	1	220	2.0e-73	269	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
637682515	388	27.6	14	369	1	364	3.0e-44	172	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637682516	304	35.92	1	304	2	294	2.0e-35	142	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
637682517	315	41.23	7	307	1	305	5.0e-37	148	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
637682518	251	48.19	2	248	1	249	8.0e-77	280	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
637682519	236	45.15	2	236	1	237	7.0e-72	263	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
637682522	212	33.8	1	208	2	212	8.0e-40	157	COG0602	Organic radical activating enzyme	212
637682523	243	32.04	49	243	57	261	8.0e-29	120	COG1729	Periplasmic TolA-binding protein (function unknown)	262
637682524	180	29.12	2	174	9	190	7.0e-28	116	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
637682525	437	40.9	22	435	2	424	8.0e-89	321	COG0823	Periplasmic component of the Tol biopolymer transport system	425
637682527	135	41.98	2	130	8	132	9.0e-25	105	COG0848	Biopolymer transport protein ExbD	137
637682528	225	41.12	12	225	1	214	6.0e-52	197	COG0811	Biopolymer transport protein ExbB/TolQ	216
637682529	140	43.38	5	140	1	135	1.0e-32	131	COG0824	Acyl-CoA thioesterase FadM	137
637682530	277	24.24	2	253	72	366	7.0e-14	71.5	COG1805	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB	400
637682531	464	48.14	5	458	18	455	6.0e-124	438	COG4402	Uncharacterized protein	457
637682532	358	71.52	17	346	2	330	0.0e+00	531	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
637682533	351	27.38	6	351	12	347	6.0e-25	108	COG0628	Predicted PurR-regulated permease PerM	355
637682534	192	50.75	1	190	1	201	2.0e-54	205	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
637682535	179	57.5	9	168	1	160	6.0e-52	196	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
637682539	241	54.55	1	241	1	241	4.0e-86	311	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
637682540	541	29.93	16	430	2	452	1.0e-42	168	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
637682542	351	28.82	3	327	12	318	9.0e-40	157	COG0226	ABC-type phosphate transport system, periplasmic component	318
637682545	147	33.33	1	143	6	149	2.0e-21	95.1	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
637682546	115	31.53	5	114	6	114	3.0e-20	90.1	COG3791	Uncharacterized conserved protein	133
637682547	294	18.03	5	293	10	292	1.0e-06	47.5	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
637682548	109	31.03	11	95	7	93	3.0e-10	57.3	COG1605	Chorismate mutase	101
637682549	291	32.32	5	291	1	297	1.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
637682550	304	43.15	5	293	1	283	1.0e-67	249	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
637682552	327	32.66	31	322	2	294	1.0e-33	137	COG0583	DNA-binding transcriptional regulator, LysR family	297
637682554	129	40.6	1	129	1	132	6.0e-21	93	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
637682555	89	48.86	1	88	1	88	2.0e-21	94.1	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
637682556	580	46.46	3	580	1	571	0.0e+00	603	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
637682557	284	21.88	31	268	31	285	4.0e-18	85.8	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
637682558	631	36.96	144	491	21	334	4.0e-43	169	COG0642	Signal transduction histidine kinase	336
637682560	750	20.18	1	750	1	699	3.0e-25	111	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
637682561	191	21.86	14	178	27	209	1.0e-08	52.9	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
637682562	705	17.75	2	705	25	768	1.0e-38	155	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
637682565	228	30.05	46	227	65	244	2.0e-10	59.4	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
637682567	197	50	1	197	1	197	3.0e-61	228	COG0307	Riboflavin synthase alpha chain	204
637682568	379	29.57	11	375	1	359	2.0e-48	186	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637682569	379	31.64	11	375	1	359	2.0e-46	180	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637682570	950	32.47	1	345	1	296	4.0e-40	160	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
637682570	950	38.36	363	677	2	314	2.0e-48	188	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
637682570	950	52.38	700	948	2	250	3.0e-80	293	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
637682571	251	55.42	10	247	1	237	9.0e-84	303	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
637682575	628	62.88	3	626	1	621	0.0e+00	970	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
637682576	205	43.81	3	202	2	211	6.0e-50	190	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
637682577	253	42.52	1	251	2	254	5.0e-63	234	COG1192	Cellulose biosynthesis protein BcsQ	259
637682578	284	39.68	29	278	7	240	9.0e-37	147	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
637682580	266	38.59	33	266	24	246	5.0e-43	168	COG0356	FoF1-type ATP synthase, membrane subunit a	246
637682581	86	46.48	10	80	9	79	1.0e-05	41.7	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
637682582	156	41.83	4	156	6	158	1.0e-13	69.5	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
637682583	178	38.2	1	177	1	178	2.0e-35	141	COG0712	FoF1-type ATP synthase, delta subunit	178
637682584	512	66.27	1	510	1	499	0.0e+00	803	COG0056	FoF1-type ATP synthase, alpha subunit	504
637682585	286	51.75	5	286	1	286	1.0e-91	329	COG0224	FoF1-type ATP synthase, gamma subunit	287
637682586	466	73.4	1	466	1	465	0.0e+00	806	COG0055	FoF1-type ATP synthase, beta subunit	468
637682587	141	48.87	4	136	3	135	1.0e-32	132	COG0355	FoF1-type ATP synthase, epsilon subunit	135
637682588	189	23.32	3	189	6	198	1.0e-16	79.9	COG3165	Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain	204
637682589	245	55.65	10	245	1	238	8.0e-79	286	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
637682590	140	50.43	7	123	1	117	1.0e-38	152	COG3536	Uncharacterized conserved protein, DUF971 family	120
637682592	143	26.19	16	136	15	138	1.0e-19	89.3	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
637682593	1291	25.88	140	670	2	445	6.0e-42	167	COG0277	FAD/FMN-containing dehydrogenase	459
637682594	141	40	10	135	17	150	1.0e-18	85.7	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
637682595	510	53.16	1	344	4	347	5.0e-122	431	COG1171	Threonine dehydratase	347
637682596	108	38.32	1	107	1	107	3.0e-13	66.7	COG4392	Branched-chain amino acid transport protein	107
637682597	233	33.91	1	228	3	230	2.0e-34	139	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
637682598	335	22.5	46	295	42	318	5.0e-06	45.8	COG5397	Uncharacterized protein	349
637682599	271	25.32	36	246	16	239	7.0e-12	65	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
637682600	310	60.26	3	302	1	300	6.0e-115	407	COG0031	Cysteine synthase	300
637682601	376	43.67	1	375	1	386	1.0e-103	370	COG1168	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	388
637682603	192	34.21	9	189	2	189	3.0e-33	134	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
637682604	642	27.09	332	623	1	296	4.0e-26	113	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
637682606	320	31.27	4	278	1	258	1.0e-26	114	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
637682607	412	35.56	1	368	23	384	4.0e-74	272	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
637682609	268	23.25	17	268	28	296	6.0e-19	88.2	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
637682612	386	39.62	22	378	7	368	1.0e-80	293	COG1565	SAM-dependent methyltransferase, MidA family	370
637682613	365	30.81	9	356	31	375	3.0e-40	159	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
637682614	916	31.79	291	635	3	335	1.0e-42	168	COG0642	Signal transduction histidine kinase	336
637682615	287	32.68	9	262	1	250	9.0e-49	187	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
637682616	299	28.14	6	165	45	207	1.0e-13	71	COG2114	Adenylate cyclase, class 3	227
637682618	311	39.59	15	306	10	302	8.0e-77	280	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
637682619	148	40	4	146	2	146	3.0e-30	124	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
637682620	108	49	1	98	1	100	2.0e-25	107	COG1544	Ribosome-associated translation inhibitor RaiA	110
637682621	489	45.93	1	489	1	443	9.0e-130	457	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
637682622	244	68.31	4	244	1	243	2.0e-107	382	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
637682623	185	40	45	184	21	165	4.0e-23	101	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
637682624	343	64.91	1	282	3	279	9.0e-87	314	COG0468	RecA/RadA recombinase	279
637682626	218	42.45	15	218	80	289	2.0e-56	212	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
637682627	515	24.9	1	483	4	485	3.0e-53	203	COG0591	Na+/proline symporter	493
637682629	898	40.11	1	893	6	909	0.0e+00	774	COG0474	Magnesium-transporting ATPase (P-type)	917
637682630	102	51.85	47	100	1	54	1.0e-16	78.4	COG3411	(2Fe-2S) ferredoxin	64
637682631	212	37.62	5	212	4	206	5.0e-48	184	COG2945	Alpha/beta superfamily hydrolase	210
637682632	314	38.82	11	310	3	293	8.0e-75	274	COG1131	ABC-type multidrug transport system, ATPase component	293
637682633	255	31.01	8	253	9	265	1.0e-36	146	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
637682634	228	33.33	18	216	16	217	2.0e-27	116	COG2045	Phosphosulfolactate phosphohydrolase or related enzyme	230
637682635	524	21.67	12	339	23	369	7.0e-21	95.8	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
637682636	299	26.72	29	285	19	272	6.0e-32	131	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
637682637	256	28.18	37	253	64	282	1.0e-05	43.7	COG0842	ABC-type multidrug transport system, permease component	286
637682638	105	50.49	1	103	1	103	3.0e-30	123	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
637682639	586	42.5	3	584	1	569	0.0e+00	500	COG4232	Thiol:disulfide interchange protein	569
637682642	416	42.51	2	412	1	409	2.0e-95	343	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
637682644	221	21.43	10	203	9	201	1.0e-18	86.6	COG4648	Uncharacterized membrane protein	201
637682645	458	21.95	15	453	68	522	1.0e-38	154	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
637682647	301	43.62	9	299	4	300	2.0e-81	296	COG4261	Predicted acyltransferase, LPLAT superfamily	309
637682649	783	35.22	2	767	12	777	0.0e+00	479	COG4258	Predicted exporter	788
637682651	266	28.57	29	263	16	255	4.0e-27	115	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
637682654	441	46.36	3	441	1	436	2.0e-130	459	COG2704	Anaerobic C4-dicarboxylate transporter	436
637682655	285	30.8	48	284	33	264	6.0e-38	151	COG3971	2-keto-4-pentenoate hydratase	264
637682656	377	25.49	20	373	1	356	9.0e-49	187	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
637682657	404	35.1	10	401	3	409	2.0e-76	279	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
637682659	149	32.85	8	142	12	146	3.0e-25	107	COG4706	Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain	161
637682660	239	45.78	1	238	5	250	2.0e-41	162	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
637682663	399	21.52	1	392	2	388	1.0e-18	87.6	COG0475	Kef-type K+ transport system, membrane component KefB	397
637682664	390	33.94	8	381	12	381	9.0e-57	214	COG3448	CBS-domain-containing membrane protein	382
637682665	252	21.18	10	251	7	253	5.0e-15	75.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
637682666	260	24.69	27	257	3	236	8.0e-13	67.6	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
637682667	282	22.35	11	269	14	256	1.0e-10	60.7	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
637682669	444	21.52	12	398	3	371	1.0e-32	134	COG0644	Dehydrogenase (flavoprotein)	396
637682671	548	23.7	11	473	13	483	7.0e-36	145	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
637682672	448	51.54	1	448	2	454	0.0e+00	528	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
637682673	547	43.85	251	543	6	305	2.0e-72	266	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
637682674	69	62.32	1	69	6	74	1.0e-27	114	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
637682675	123	33.62	5	120	1	115	2.0e-12	64.5	COG0594	RNase P protein component	117
639329065	405	44.35	29	399	13	375	2.0e-82	299	COG3328	Transposase (or an inactivated derivative)	379
639329069	130	28.57	4	92	1	90	7.0e-09	53	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
639329074	576	40.03	5	568	10	595	0.0e+00	488	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
639329077	424	18.55	89	424	82	440	7.0e-21	95.4	COG2067	Long-chain fatty acid transport protein	440
639329081	354	32.65	1	285	18	304	1.0e-54	207	COG4644	Transposase and inactivated derivatives, TnpA family	323
