gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
644375961	322	46.81	90	319	2	236	6.0e-56	211	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
644375962	238	29.72	1	232	1	245	2.0e-31	129	COG1521	Pantothenate kinase type III	251
644375964	263	24.88	24	236	12	213	1.0e-10	60.3	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
644375965	654	49.15	13	654	1	616	0.0e+00	620	COG3211	Secreted phosphatase, PhoX family	616
644375966	321	37.38	25	316	3	305	1.0e-63	236	COG0010	Arginase family enzyme	305
644375968	241	35.34	1	241	2	245	2.0e-24	106	COG0368	Cobalamin synthase	246
644375969	200	36.92	5	194	4	198	4.0e-26	111	COG0406	Broad specificity phosphatase PhoE	208
644375970	348	44.83	1	347	3	337	2.0e-67	249	COG2038	NaMN:DMB phosphoribosyltransferase	347
644375971	200	48.57	1	172	1	175	1.0e-48	186	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
644375973	103	35.56	6	95	3	92	2.0e-12	64.2	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
644375974	200	36.6	4	192	3	190	6.0e-33	133	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
644375978	152	56.67	1	149	2	148	3.0e-50	190	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
644375979	268	32.73	1	268	1	256	2.0e-10	60	COG0730	Uncharacterized membrane protein YfcA	258
644375980	313	25.65	30	294	19	265	1.0e-17	84.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644375981	872	51.54	1	872	1	814	0.0e+00	1048	COG0495	Leucyl-tRNA synthetase	814
644375982	176	35.06	3	176	2	172	8.0e-25	106	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
644375983	334	32.8	16	328	14	326	6.0e-55	208	COG1466	DNA polymerase III, delta subunit	334
644375986	130	44.07	5	122	25	140	1.0e-15	75.4	COG3753	Uncharacterized conserved protein YidB, DUF937 family	143
644375987	172	45.4	2	170	5	178	2.0e-39	155	COG4549	Uncharacterized protein YcnI	178
644375988	156	50.32	1	155	1	155	4.0e-54	203	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
644375989	122	44.25	1	113	1	113	5.0e-32	129	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
644375990	213	38.86	1	211	1	195	9.0e-47	180	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
644375991	192	32.83	1	182	1	196	6.0e-34	137	COG0288	Carbonic anhydrase	207
644375993	450	65.26	1	447	1	448	0.0e+00	618	COG0439	Biotin carboxylase	449
644375995	149	44.52	6	149	1	139	2.0e-25	108	COG0511	Biotin carboxyl carrier protein	140
644375996	408	25.14	34	397	35	384	3.0e-18	86.4	COG2814	Predicted arabinose efflux permease, MFS family	394
644375997	265	57.77	10	259	13	263	1.0e-91	329	COG4336	Uncharacterized protein YcsI, UPF0317 family	265
644375998	246	62	1	245	2	251	1.0e-90	326	COG1540	Lactam utilization protein B (function unknown)	252
644375999	308	56.23	2	308	1	313	8.0e-106	376	COG1984	Allophanate hydrolase subunit 2	314
644376000	220	51.4	8	218	1	214	9.0e-66	243	COG2049	Allophanate hydrolase subunit 1	223
644376001	169	44.79	7	169	37	199	5.0e-50	190	COG5631	Predicted transcription regulator, contains HTH domain, MarR family	199
644376002	286	31.28	1	221	11	227	7.0e-21	94.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644376003	113	35.71	1	97	2	99	7.0e-08	49	COG0640	DNA-binding transcriptional regulator, ArsR family	110
644376004	142	36.42	1	142	11	161	4.0e-07	47.3	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
644376006	556	33.83	8	541	12	539	2.0e-83	303	COG0659	Sulfate permease or related transporter, MFS superfamily	554
644376007	479	30.42	3	478	12	484	2.0e-69	257	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
644376008	888	66.07	1	884	1	883	0.0e+00	1357	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
644376009	536	44.21	108	536	3	403	3.0e-100	359	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
644376010	593	49.57	117	577	2	454	0.0e+00	472	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
644376012	589	29.56	37	589	39	594	6.0e-80	291	COG0729	Outer membrane translocation and assembly module TamA	594
644376013	1274	27.04	18	1273	2	1278	1.0e-124	441	COG2911	Autotransporter translocation and assembly factor TamB	1278
644376015	342	47.08	1	322	2	323	3.0e-93	335	COG0042	tRNA-dihydrouridine synthase	323
644376016	78	54.93	7	77	27	97	9.0e-21	91.6	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
644376017	534	67.24	13	534	2	515	0.0e+00	783	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
644376019	426	60.89	1	425	1	426	0.0e+00	592	COG0151	Phosphoribosylamine-glycine ligase	428
644376020	242	21.46	1	241	3	263	4.0e-18	85.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644376021	171	43.68	2	171	23	195	8.0e-40	156	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
644376022	216	44.55	3	212	1	211	2.0e-49	189	COG0811	Biopolymer transport protein ExbB/TolQ	216
644376023	293	21.35	15	285	13	283	3.0e-06	45.9	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
644376024	146	34.23	1	143	6	154	3.0e-26	110	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644376025	229	50.22	4	228	2	228	2.0e-65	242	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644376026	434	31.61	107	422	120	445	1.0e-51	197	COG5002	Signal transduction histidine kinase	459
644376027	352	21.05	11	352	3	238	3.0e-30	126	COG0176	Transaldolase	239
644376030	621	62.06	1	621	7	627	0.0e+00	836	COG3158	K+ transporter	627
644376031	571	42.68	1	563	1	496	0.0e+00	550	COG0442	Prolyl-tRNA synthetase	500
644376032	230	28.23	12	212	52	260	1.0e-13	70.6	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
644376033	436	32.88	1	432	2	420	5.0e-70	258	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
644376034	171	28.75	4	163	14	170	4.0e-07	48.2	COG1714	Uncharacterized membrane protein YckC, RDD family	172
644376035	586	51.06	2	565	1	550	0.0e+00	678	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
644376036	163	53.42	1	161	3	163	2.0e-47	181	COG0440	Acetolactate synthase, small subunit	163
644376037	338	66.07	1	336	3	338	0.0e+00	542	COG0059	Ketol-acid reductoisomerase	338
644376038	279	32.35	8	275	1	237	4.0e-53	202	COG0688	Phosphatidylserine decarboxylase	239
644376039	259	40.52	13	242	2	228	3.0e-48	185	COG1183	Phosphatidylserine synthase	234
644376040	597	54	87	496	1	406	1.0e-121	430	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
644376041	207	51.46	1	205	2	203	1.0e-58	219	COG0132	Dethiobiotin synthetase	223
644376042	371	33.85	7	260	2	233	2.0e-57	216	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
644376043	542	58.69	14	525	1	517	0.0e+00	562	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
644376044	181	34.46	4	175	5	178	1.0e-37	149	COG3175	Cytochrome c oxidase assembly protein Cox11	195
644376046	285	36.44	61	285	10	206	2.0e-38	153	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
644376050	338	33.96	8	309	28	310	8.0e-33	134	COG1612	Heme A synthase	323
644376051	299	47.44	1	293	6	298	2.0e-71	262	COG0109	Polyprenyltransferase (heme O synthase)	304
644376052	195	45.55	8	195	15	205	1.0e-45	176	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
644376053	268	24.35	39	266	5	229	2.0e-18	86.5	COG5581	c-di-GMP-binding flagellar brake protein YcgR, contains PilZNR and PilZ domains	233
644376054	213	49.77	1	213	1	215	6.0e-59	220	COG0040	ATP phosphoribosyltransferase	290
644376055	430	53.95	1	430	1	423	0.0e+00	541	COG0141	Histidinol dehydrogenase	425
644376056	356	43.3	8	356	1	353	3.0e-78	285	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
644376057	199	61.42	1	197	1	195	3.0e-79	288	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
644376058	213	53.99	1	211	2	204	4.0e-76	277	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
644376059	246	51.03	1	243	2	240	6.0e-78	283	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
644376060	255	73.62	3	255	2	255	7.0e-117	413	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
644376061	128	62.86	3	107	7	111	3.0e-45	173	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
644376062	108	50.56	6	94	1	89	8.0e-21	92.2	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
644376063	107	53.4	2	104	1	103	7.0e-28	115	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
644376065	172	31.11	1	90	1	87	1.0e-11	63.1	COG1826	Sec-independent protein translocase protein TatA	94
644376066	242	52.67	1	240	5	247	1.0e-57	216	COG0805	Sec-independent protein secretion pathway component TatC	255
644376067	116	52.73	1	108	10	118	2.0e-20	90.8	COG3308	Uncharacterized membrane protein	131
644376068	719	34.97	18	708	11	696	0.0e+00	559	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
644376069	472	20.44	57	449	9	341	3.0e-13	70	COG1566	Multidrug resistance efflux pump	352
644376070	204	25.7	27	203	31	204	1.0e-17	83.5	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644376074	640	28.51	413	634	6	233	2.0e-21	98.1	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644376076	499	25.06	27	427	45	451	2.0e-46	180	COG1538	Outer membrane protein TolC	457
644376077	261	39.61	11	260	3	256	1.0e-61	230	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
644376079	248	33.48	23	243	9	219	6.0e-35	141	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
644376080	137	33.82	3	136	2	131	2.0e-27	114	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
644376081	142	41.46	1	123	1	123	4.0e-32	130	COG3795	Uncharacterized conserved protein	123
644376083	277	50.55	2	272	10	275	3.0e-82	298	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
644376085	111	44.95	3	109	3	111	2.0e-28	117	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
644376086	196	58.66	3	181	1	176	7.0e-60	223	COG0279	Phosphoheptose isomerase	176
644376087	193	40.86	8	188	10	195	5.0e-30	124	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
644376088	401	32.73	19	235	20	239	2.0e-37	150	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644376089	302	22.64	43	301	4	279	1.0e-09	57.3	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
644376090	233	52.23	1	157	2	151	1.0e-44	172	COG1720	tRNA (Thr-GGU) A37 N-methylase	156
644376091	249	38.65	12	249	35	285	8.0e-44	170	COG3176	Putative hemolysin	292
644376092	630	62.08	3	626	1	621	0.0e+00	971	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
644376093	208	49.05	3	205	1	210	4.0e-55	207	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
644376094	263	42.25	4	259	3	259	6.0e-61	227	COG1192	Cellulose biosynthesis protein BcsQ	259
644376095	284	39.44	24	272	3	238	6.0e-33	134	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
644376097	269	38.91	1	269	5	246	4.0e-45	175	COG0356	FoF1-type ATP synthase, membrane subunit a	246
644376099	156	42.31	1	156	3	158	3.0e-19	88	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
644376100	178	42.13	1	177	1	178	2.0e-37	148	COG0712	FoF1-type ATP synthase, delta subunit	178
644376101	514	65.95	1	514	1	503	0.0e+00	810	COG0056	FoF1-type ATP synthase, alpha subunit	504
644376102	288	50.7	5	288	1	286	5.0e-93	334	COG0224	FoF1-type ATP synthase, gamma subunit	287
644376103	464	75.32	1	464	1	465	0.0e+00	827	COG0055	FoF1-type ATP synthase, beta subunit	468
644376104	140	49.63	1	135	1	135	1.0e-33	135	COG0355	FoF1-type ATP synthase, epsilon subunit	135
644376105	454	55.8	4	454	3	459	0.0e+00	624	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
644376106	561	51.68	1	535	1	525	0.0e+00	701	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
644376108	212	48.56	1	208	1	205	1.0e-67	249	COG2808	Predicted FMN-binding regulatory protein PaiB	209
644376109	206	39.6	5	204	7	208	2.0e-19	89.2	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644376110	231	38.6	1	226	2	226	5.0e-63	234	COG3382	B3/B4 domain (DNA/RNA-binding domain of Phe-tRNA-synthetase)	229
644376112	266	44.94	2	266	13	278	3.0e-84	305	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
644376113	392	53.47	1	388	11	394	9.0e-76	277	COG2814	Predicted arabinose efflux permease, MFS family	394
644376114	298	38.18	4	294	2	292	4.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376115	409	20.96	14	409	4	393	3.0e-12	66.8	COG2814	Predicted arabinose efflux permease, MFS family	394
644376116	185	32.42	6	183	21	202	5.0e-23	100	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
644376119	236	34.48	8	236	5	236	6.0e-50	190	COG2188	DNA-binding transcriptional regulator, GntR family	236
644376120	218	38.62	22	210	5	193	6.0e-38	150	COG3758	Various environmental stresses-induced protein Ves (function unknown)	193
644376121	463	27.97	4	452	2	421	1.0e-53	204	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
644376122	267	47.39	1	266	4	270	6.0e-76	277	COG3741	N-formylglutamate amidohydrolase	272
644376123	263	36.22	133	259	1	127	4.0e-19	88.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644376125	308	34.45	3	296	2	291	3.0e-33	135	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376126	202	50.99	1	201	2	202	4.0e-63	234	COG1182	FMN-dependent NADH-azoreductase	202
644376128	352	39.78	5	352	2	353	8.0e-79	287	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
644376130	153	48	1	149	6	154	1.0e-28	119	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644376131	302	72.54	9	302	10	303	0.0e+00	490	COG0408	Coproporphyrinogen III oxidase	303
644376132	205	38.83	1	199	1	200	7.0e-38	150	COG0625	Glutathione S-transferase	211
644376133	347	49.7	6	343	6	334	7.0e-70	257	COG2855	Uncharacterized membrane protein YadS	334
644376134	290	33.22	5	287	1	286	1.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376135	356	35.63	1	347	2	327	2.0e-76	279	COG0460	Homoserine dehydrogenase	333
644376136	476	43.04	12	473	11	472	2.0e-109	389	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644376137	262	64.45	4	259	1	255	2.0e-106	378	COG4598	ABC-type histidine transport system, ATPase component	256
644376138	262	29.78	1	258	4	269	7.0e-33	134	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644376139	222	48.9	3	222	2	228	1.0e-56	213	COG4215	ABC-type arginine transport system, permease component	230
644376140	229	50.23	10	226	7	225	5.0e-58	217	COG4160	ABC-type arginine/histidine transport system, permease component	228
644376141	389	45.15	2	389	5	395	2.0e-114	406	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
644376142	151	36.6	1	151	1	152	6.0e-20	90.1	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644376143	159	31.82	1	154	2	154	5.0e-20	90.5	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644376145	312	33.44	1	305	5	318	9.0e-56	210	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
644376147	242	42.93	44	224	13	196	2.0e-45	175	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
644376148	887	59.57	290	887	3	593	0.0e+00	781	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
644376149	188	26.74	5	188	2	178	1.0e-19	89.3	COG4970	Tfp pilus assembly protein FimT	181
644376152	216	26.83	10	213	11	190	6.0e-19	87.8	COG4726	Tfp pilus assembly protein PilX	196
644376154	141	44.72	7	124	4	126	6.0e-25	106	COG4968	Tfp pilus assembly protein PilE	139
644376156	383	43.2	5	341	7	344	3.0e-74	272	COG1566	Multidrug resistance efflux pump	352
644376157	460	36.32	5	460	1	452	1.0e-39	157	COG1538	Outer membrane protein TolC	457
644376158	164	27.27	42	162	9	124	1.0e-10	59.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
644376159	116	39.13	1	115	2	116	9.0e-27	112	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
644376160	412	21.2	7	353	2	340	7.0e-18	85.3	COG2814	Predicted arabinose efflux permease, MFS family	394
644376161	181	55	1	177	3	179	3.0e-60	224	COG3470	Uncharacterized protein probably involved in high-affinity Fe2+ transport	179
644376163	273	27.15	3	264	9	299	2.0e-23	103	COG0672	High-affinity Fe2+/Pb2+ permease	383
644376165	160	35.95	9	160	2	154	1.0e-30	126	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
644376166	142	35.71	3	142	11	144	8.0e-21	92.8	COG0071	Molecular chaperone IbpA, HSP20 family	146
644376167	225	43	25	223	6	205	5.0e-42	164	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
644376168	302	44.58	26	273	32	266	7.0e-61	227	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
644376169	268	48.34	1	264	2	271	3.0e-87	315	COG1242	Radical SAM superfamily enzyme	312
644376171	380	53.08	1	373	4	367	7.0e-126	443	COG2021	Homoserine acetyltransferase	368
644376174	200	30.77	1	197	3	207	3.0e-29	121	COG0655	Multimeric flavodoxin WrbA	207
644376175	403	29.56	11	273	17	289	2.0e-34	140	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
644376178	469	61.73	216	458	4	244	1.0e-89	324	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
644376179	133	39.55	1	130	1	133	2.0e-21	94.6	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
644376180	89	46.59	1	88	1	88	4.0e-23	99.5	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
644376181	579	44.08	3	576	1	572	0.0e+00	611	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
644376182	361	35.43	11	358	1	332	9.0e-54	204	COG0859	ADP-heptose:LPS heptosyltransferase	334
644376183	381	23.39	1	374	1	378	7.0e-27	115	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644376184	586	39.97	10	582	1	567	0.0e+00	479	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
644376185	365	29.03	26	362	51	381	3.0e-32	133	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644376186	272	23.01	5	234	7	230	2.0e-13	70	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
644376187	337	27.02	10	284	1	277	5.0e-31	128	COG0859	ADP-heptose:LPS heptosyltransferase	334
644376188	370	27.65	1	370	1	375	4.0e-40	159	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644376189	391	23.8	1	391	3	378	2.0e-27	116	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644376190	351	24.2	54	351	73	378	1.0e-18	87.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644376191	397	18.34	21	352	38	382	4.0e-06	46.3	COG3307	O-antigen ligase	424
644376192	373	24.1	22	362	3	334	5.0e-36	145	COG0859	ADP-heptose:LPS heptosyltransferase	334
644376193	427	40.09	2	421	8	432	8.0e-119	420	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
644376195	362	59.38	1	356	1	355	0.0e+00	476	COG0337	3-dehydroquinate synthetase	360
644376196	169	52.5	1	157	11	170	6.0e-48	183	COG0703	Shikimate kinase	172
644376197	691	32.2	7	685	8	709	2.0e-105	377	COG4796	Type II secretory pathway, component HofQ	709
644376198	170	39.38	9	166	10	168	7.0e-34	136	COG3168	Tfp pilus assembly protein PilP	170
644376199	211	42.18	2	210	4	211	5.0e-43	167	COG3167	Tfp pilus assembly protein PilO	211
644376200	194	33.51	1	191	4	191	1.0e-24	106	COG3166	Tfp pilus assembly protein PilN	206
644376201	370	41.74	15	370	1	354	4.0e-85	308	COG4972	Tfp pilus assembly protein, ATPase PilM	354
644376202	750	50.2	1	734	47	794	0.0e+00	864	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
644376208	282	26.83	7	241	3	237	6.0e-40	158	COG0338	Site-specific DNA-adenine methylase	274
644376224	132	29.35	22	111	2	93	6.0e-07	46.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
644376225	324	27.4	104	320	2	209	7.0e-20	91.7	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
644376234	540	28.94	2	535	19	537	2.0e-102	366	COG4626	Phage terminase-like protein, large subunit, contains N-terminal HTH domain	546
644376235	421	32.89	38	411	27	395	1.0e-54	207	COG4695	Phage portal protein BeeE	398
644376236	238	24.47	14	198	10	197	3.0e-31	128	COG0740	ATP-dependent protease ClpP, protease subunit	200
644376237	413	21.48	24	413	25	421	5.0e-32	132	COG4653	Predicted phage phi-C31 gp36 major capsid-like protein	422
644376245	494	46.26	1	491	1	487	2.0e-119	423	COG4386	Mu-like prophage tail sheath protein gpL	487
644376249	397	22.65	3	388	5	441	5.0e-29	122	COG4228	Mu-like prophage DNA circulation protein	451
644376250	377	28.96	10	364	3	364	1.0e-52	200	COG4379	Mu-like prophage tail protein gpP	386
644376251	184	28.42	1	181	10	199	2.0e-27	115	COG4384	Mu-like prophage protein gp45	203
644376252	138	28.68	6	134	16	134	1.0e-11	62	COG4381	Mu-like prophage protein gp46	135
644376253	365	26.37	2	365	1	351	1.0e-31	130	COG3299	Uncharacterized phage protein gp47/JayE	353
644376254	194	29.84	1	191	1	186	3.0e-27	115	COG3778	Uncharacterized protein YmfQ in lambdoid prophage, DUF2313 family	188
644376258	185	45.15	6	185	5	206	6.0e-39	153	COG3179	Predicted chitinase	206
644376262	360	40.12	44	360	3	322	3.0e-81	295	COG0142	Geranylgeranyl pyrophosphate synthase	322
644376263	103	53.92	1	102	1	102	8.0e-31	125	COG0261	Ribosomal protein L21	103
644376264	91	72.09	1	86	1	85	4.0e-31	126	COG0211	Ribosomal protein L27	87
644376265	388	55.95	1	369	1	354	0.0e+00	493	COG0536	GTPase involved in cell partioning and DNA repair	369
644376270	299	24.75	1	299	4	286	6.0e-09	54.9	COG5006	Threonine/homoserine efflux transporter RhtA	292
644376271	131	42.86	9	124	3	121	1.0e-19	88.9	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
644376272	547	30.62	14	460	20	461	2.0e-38	154	COG0531	Amino acid transporter	466
644376273	165	66.46	1	158	1	158	4.0e-63	233	COG2077	Peroxiredoxin	158
644376274	548	30.66	164	525	50	408	3.0e-39	157	COG0840	Methyl-accepting chemotaxis protein	408
644376277	334	36.73	48	332	24	303	1.0e-30	127	COG3391	DNA-binding beta-propeller fold protein YncE	381
644376278	187	48.26	4	175	3	167	1.0e-52	198	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
644376279	679	56.85	1	674	7	682	0.0e+00	886	COG0339	Zn-dependent oligopeptidase	683
644376280	539	41.09	1	538	4	545	0.0e+00	517	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
644376281	257	45.25	1	257	1	261	1.0e-84	306	COG0708	Exonuclease III	261
644376282	279	35.45	1	260	1	261	2.0e-51	196	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
644376285	229	46.32	1	228	4	233	3.0e-52	198	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
644376286	681	37.03	4	670	5	687	0.0e+00	562	COG0480	Translation elongation factor EF-G, a GTPase	697
644376287	259	31.6	1	256	2	266	8.0e-52	197	COG1018	Ferredoxin-NADP reductase	266
644376288	314	30.77	7	299	2	297	8.0e-27	114	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376289	122	46.96	4	114	14	128	5.0e-08	50	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
644376290	285	42.76	9	285	5	275	3.0e-62	232	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
644376291	293	35.84	1	275	5	276	8.0e-58	217	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
644376293	347	29.41	1	329	1	374	6.0e-32	131	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644376294	282	38.59	16	253	1	237	2.0e-64	238	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
644376296	184	43.32	11	184	6	192	6.0e-42	163	COG3658	Cytochrome b	192
644376297	220	46.52	1	220	1	229	1.0e-55	209	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644376298	428	29.63	107	425	8	325	9.0e-34	138	COG0642	Signal transduction histidine kinase	336
644376299	126	30.28	12	119	2	108	6.0e-17	79.6	COG0607	Rhodanese-related sulfurtransferase	110
644376300	643	55.52	1	642	1	636	0.0e+00	852	COG4263	Nitrous oxide reductase	637
644376301	135	46.72	13	133	7	124	3.0e-15	74.3	COG3245	Cytochrome c5	126
644376304	169	43.02	3	169	2	173	9.0e-36	142	COG4314	Nitrous oxide reductase accessory protein NosL	176
644376305	271	28.26	4	271	1	273	1.0e-13	70.5	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
644376306	306	39.87	4	303	3	292	2.0e-69	256	COG1131	ABC-type multidrug transport system, ATPase component	293
644376307	427	45.15	9	417	3	408	2.0e-124	439	COG3420	Nitrous oxidase accessory protein NosD, contains tandem CASH domains	408
644376308	730	36.46	14	474	12	478	2.0e-113	403	COG3901	Regulator of nitric oxide reductase transcription	482
644376309	420	19.52	104	418	5	334	2.0e-10	60.6	COG0642	Signal transduction histidine kinase	336
644376310	175	56.14	5	174	12	182	3.0e-50	191	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
644376311	215	46.38	4	209	3	194	8.0e-43	167	COG3145	Alkylated DNA repair dioxygenase AlkB	194
644376312	370	46.45	15	197	7	187	7.0e-56	211	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
644376313	187	30.57	33	185	28	179	6.0e-13	67.2	COG2065	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	179
644376314	265	21.78	27	244	37	258	4.0e-15	75.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644376315	460	40.35	7	460	1	456	1.0e-86	314	COG0277	FAD/FMN-containing dehydrogenase	459
644376316	207	35.15	4	195	1	199	2.0e-18	85.6	COG0625	Glutathione S-transferase	211
644376317	451	42.01	2	451	14	468	1.0e-108	386	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644376318	390	25.85	5	383	3	333	2.0e-48	186	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
644376319	230	33.33	4	190	14	205	1.0e-30	126	COG1180	Pyruvate-formate lyase-activating enzyme	260
644376321	577	28.92	21	577	100	674	0.0e+00	555	COG1328	Anaerobic ribonucleoside-triphosphate reductase	700
644376322	143	43.85	13	142	17	145	3.0e-37	147	COG3019	Uncharacterized conserved protein	149
644376323	318	30.13	3	299	2	296	3.0e-42	165	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376324	428	31.82	27	408	1	387	2.0e-53	203	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644376326	1141	34.04	452	734	69	332	1.0e-38	155	COG0642	Signal transduction histidine kinase	336
644376327	144	28.68	8	143	8	142	2.0e-16	78.4	COG3154	Predicted lipid carrier protein YhbT, SCP2 domain	168
644376328	313	26.45	13	310	1	308	5.0e-49	188	COG0826	Collagenase-like protease, PrtC family	347
644376329	334	36.87	1	334	4	312	3.0e-74	272	COG0826	Collagenase-like protease, PrtC family	347
644376330	126	41.13	3	122	2	125	3.0e-16	77.2	COG3094	Uncharacterized membrane protein SirB2	129
644376331	1061	39.1	1	1049	1	1073	0.0e+00	790	COG1330	Exonuclease V gamma subunit	1078
644376334	517	44.9	247	489	21	265	7.0e-77	281	COG2326	Polyphosphate kinase 2, PPK2 family	270
644376335	567	30.81	76	564	152	692	1.0e-77	284	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
644376337	500	30.63	169	500	21	336	2.0e-34	141	COG0642	Signal transduction histidine kinase	336
644376338	227	45.65	1	222	1	229	2.0e-50	192	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644376339	327	40.49	4	327	1	319	4.0e-76	278	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
644376341	506	55.33	1	496	1	495	0.0e+00	564	COG3333	TctA family transporter	504
644376342	347	38.1	12	343	14	349	2.0e-44	173	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
644376343	235	29.88	1	230	7	254	4.0e-34	138	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
644376344	953	39.11	678	925	2	247	7.0e-62	232	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644376345	228	43.86	3	228	2	228	8.0e-60	223	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644376346	227	34.1	10	220	11	227	2.0e-31	129	COG2063	Flagellar basal body L-ring protein FlgH	230
644376348	461	36.38	39	455	20	445	2.0e-41	163	COG1538	Outer membrane protein TolC	457
644376349	389	30.07	10	389	1	419	2.0e-33	137	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
644376353	241	45.37	14	238	1	225	2.0e-55	209	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644376354	353	34.24	63	353	44	330	2.0e-35	143	COG0642	Signal transduction histidine kinase	336
644376356	245	48.18	44	148	17	126	4.0e-21	95.1	COG3245	Cytochrome c5	126
644376357	267	41.61	97	255	1	161	1.0e-33	136	COG1656	Uncharacterized conserved protein, contains PIN domain	165
644376358	138	22.73	5	136	11	138	2.0e-07	48.8	COG5622	Protein required for attachment to host cells	139
644376359	672	43.88	5	645	2	654	0.0e+00	565	COG0210	Superfamily I DNA or RNA helicase	655
644376362	272	57.51	1	271	1	273	1.0e-99	356	COG0266	Formamidopyrimidine-DNA glycosylase	273
644376364	181	30.46	3	180	8	203	2.0e-25	109	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
644376365	280	49.12	6	276	4	286	7.0e-87	313	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
644376367	327	60.51	5	316	3	314	7.0e-118	417	COG0462	Phosphoribosylpyrophosphate synthetase	314
644376368	192	45.74	2	95	1	93	6.0e-24	104	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
644376369	194	53.97	3	191	1	188	9.0e-72	263	COG0193	Peptidyl-tRNA hydrolase	190
644376370	363	63.71	1	363	1	372	0.0e+00	516	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
644376371	259	36.33	1	256	5	271	3.0e-41	162	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644376372	219	50	3	217	7	222	4.0e-54	204	COG0765	ABC-type amino acid transport system, permease component	222
644376373	380	51.03	1	380	6	393	0.0e+00	475	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
644376375	258	27.41	4	258	1	266	2.0e-41	163	COG1018	Ferredoxin-NADP reductase	266
644376376	780	41.23	168	780	1	557	0.0e+00	587	COG1982	Arginine/lysine/ornithine decarboxylase	557
644376377	506	31.36	1	386	27	430	1.0e-54	207	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
644376378	1482	57.77	703	1174	5	479	0.0e+00	636	COG0069	Glutamate synthase domain 2	485
644376379	471	45.05	23	468	2	450	8.0e-127	447	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
644376380	470	55.39	1	333	2	333	0.0e+00	482	COG0836	Mannose-1-phosphate guanylyltransferase	333
644376387	387	32.07	11	372	14	354	3.0e-70	259	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
644376389	373	71.71	1	357	1	345	0.0e+00	592	COG1089	GDP-D-mannose dehydratase	345
644376390	181	59.89	1	177	1	173	1.0e-61	229	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
644376391	294	58.13	3	291	1	286	3.0e-117	414	COG1209	dTDP-glucose pyrophosphorylase	286
644376392	296	47.44	3	295	2	281	3.0e-91	328	COG1091	dTDP-4-dehydrorhamnose reductase	281
644376397	95	61.05	1	95	1	95	3.0e-31	126	COG0234	Co-chaperonin GroES (HSP10)	96
644376398	545	48.91	1	534	1	524	0.0e+00	495	COG0459	Chaperonin GroEL (HSP60 family)	524
644376399	248	38.65	1	248	1	250	3.0e-62	231	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
644376400	194	34.2	1	193	2	168	2.0e-30	126	COG0723	Rieske Fe-S protein	177
644376401	439	51.38	1	398	1	377	4.0e-95	341	COG1290	Cytochrome b subunit of the bc complex	381
644376402	253	35.94	1	253	5	250	4.0e-53	201	COG2857	Cytochrome c1	250
644376403	216	34.67	18	203	1	198	7.0e-31	127	COG0625	Glutathione S-transferase	211
644376404	147	45.39	1	147	4	155	1.0e-45	175	COG2969	Stringent starvation protein B	155
644376405	434	59.66	33	433	1	401	3.0e-123	435	COG0004	Ammonia channel protein AmtB	409
644376406	112	69.64	1	112	1	112	6.0e-39	152	COG0347	Nitrogen regulatory protein PII	112
644376407	95	41.94	1	90	10	102	2.0e-14	70.4	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
644376408	500	57.82	15	494	1	486	0.0e+00	595	COG0606	Predicted ATPase with chaperone activity	490
644376409	242	19.47	16	240	3	261	5.0e-11	61.6	COG3087	Cell division protein FtsN	264
644376411	273	44.65	1	267	1	270	6.0e-65	241	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
644376413	456	33.19	12	456	1	435	2.0e-107	382	COG0015	Adenylosuccinate lyase	438
644376415	452	60.84	1	452	1	449	0.0e+00	615	COG0541	Signal recognition particle GTPase	451
644376416	273	38.78	10	272	6	265	2.0e-41	163	COG4137	ABC-type uncharacterized transport system, permease component	265
644376418	469	45.73	2	463	1	457	3.0e-126	445	COG0415	Deoxyribodipyrimidine photolyase	461
644376419	354	22.4	1	349	1	342	7.0e-32	131	COG3203	Outer membrane protein (porin)	354
644376420	569	49.4	67	569	5	500	0.0e+00	569	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
644376421	408	42.68	15	408	3	397	2.0e-110	392	COG1459	Type II secretory pathway, component PulF	397
644376422	288	46.52	15	286	2	251	5.0e-37	148	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
644376423	176	38.55	2	167	30	194	5.0e-37	147	COG0237	Dephospho-CoA kinase	201
644376424	239	30.08	2	237	15	244	2.0e-53	202	COG4582	Cell division protein ZapD, interacts with FtsZ	244
644376425	64	53.23	1	62	1	62	2.0e-14	70.9	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
644376426	410	34.13	112	404	2	231	5.0e-51	195	COG0860	N-acetylmuramoyl-L-alanine amidase	231
644376427	163	52.41	13	156	5	149	1.0e-45	175	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
644376428	367	54.09	14	354	2	337	3.0e-98	352	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
644376429	270	50	2	270	1	268	6.0e-81	294	COG0796	Glutamate racemase	269
644376430	141	39.86	1	140	12	159	3.0e-25	107	COG2030	Acyl dehydratase	159
644376431	249	51.15	1	249	1	260	2.0e-67	249	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
644376432	311	56.6	1	311	1	312	2.0e-85	309	COG2025	Electron transfer flavoprotein, alpha subunit	313
644376433	593	37.12	35	453	7	387	4.0e-69	256	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644376434	375	61.23	3	375	1	366	0.0e+00	568	COG0505	Carbamoylphosphate synthase small subunit	368
644376435	215	37.68	8	214	7	208	3.0e-23	101	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644376436	1070	69.7	13	408	1	393	0.0e+00	582	COG0458	Carbamoylphosphate synthase large subunit	400
644376437	158	54.9	6	158	1	151	5.0e-38	150	COG0782	Transcription elongation factor, GreA/GreB family	151
644376439	110	42.39	11	101	6	97	3.0e-21	93.7	COG1534	RNA-binding protein YhbY	97
644376440	205	57.92	4	205	1	202	4.0e-72	264	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
644376441	636	62.69	9	606	1	596	0.0e+00	786	COG0465	ATP-dependent Zn proteases	596
644376442	280	52.04	14	278	6	267	2.0e-66	246	COG0294	Dihydropteroate synthase	274
644376443	445	45.57	1	445	5	462	3.0e-116	412	COG1109	Phosphomannomutase	464
644376444	216	25.89	9	205	7	202	4.0e-31	128	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
644376446	260	26.85	10	256	28	280	2.0e-25	109	COG5473	Uncharacterized membrane protein	290
644376447	316	40.31	5	316	4	321	7.0e-83	301	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
644376449	159	52.17	1	159	2	162	1.0e-58	218	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
644376450	226	46.64	8	225	2	224	8.0e-66	243	COG0220	tRNA G46 methylase TrmB	227
644376451	292	23.76	1	278	1	296	9.0e-17	81.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
644376452	342	34.06	100	327	5	222	5.0e-49	188	COG0543	NAD(P)H-flavin reductase	252
644376454	185	48.02	8	184	3	179	1.0e-48	186	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
644376455	432	60.37	1	432	3	436	4.0e-121	428	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
644376456	208	54.64	6	188	4	185	2.0e-68	251	COG0194	Guanylate kinase	191
644376457	68	47.14	1	68	1	70	4.0e-14	69.6	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
644376458	722	43.94	20	721	6	700	0.0e+00	809	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
644376459	66	46.97	1	66	3	68	2.0e-11	60.6	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
644376460	264	61.69	1	261	3	260	6.0e-98	350	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
644376461	70	60.94	1	64	1	64	1.0e-07	48	COG0828	Ribosomal protein S21	67
644376462	148	57.43	1	147	1	148	2.0e-37	148	COG1610	Uncharacterized conserved protein YqeY	148
644376463	587	38.58	1	586	1	563	1.0e-124	440	COG0358	DNA primase (bacterial type)	568
644376464	640	46.24	278	634	1	342	1.0e-94	341	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
644376467	290	31.6	4	241	1	247	8.0e-26	111	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376468	400	18.86	22	390	48	441	7.0e-08	52.1	COG2271	Sugar phosphate permease	448
644376470	231	36.82	16	231	19	227	6.0e-33	134	COG4291	Uncharacterized membrane protein	228
644376471	221	40.96	27	214	3	185	5.0e-30	124	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
644376472	118	41.12	8	114	13	119	1.0e-15	75.2	COG0818	Diacylglycerol kinase	123
644376474	178	27.22	1	169	2	167	4.0e-29	120	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
644376475	369	30.41	8	339	17	346	7.0e-43	168	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
644376477	250	37.19	4	244	1	239	6.0e-48	184	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
644376478	309	19.94	1	308	3	269	3.0e-19	89.4	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
644376479	319	23.39	47	256	14	230	4.0e-13	69.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644376480	257	27.66	10	145	11	147	1.0e-09	57	COG5501	Predicted secreted protein	148
644376481	275	22.99	1	265	2	262	1.0e-13	70.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644376483	129	58.04	1	112	3	114	2.0e-41	160	COG3564	Uncharacterized conserved protein, DUF779 family	116
644376484	506	45.7	19	501	1	472	0.0e+00	510	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644376485	856	27.33	381	711	7	334	7.0e-34	139	COG0642	Signal transduction histidine kinase	336
644376486	385	33.59	8	378	4	379	1.0e-62	234	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
644376488	258	22.22	5	253	17	253	3.0e-07	49.4	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
644376489	241	38.86	1	225	1	229	4.0e-54	204	COG1131	ABC-type multidrug transport system, ATPase component	293
644376490	324	28.62	25	324	44	348	2.0e-28	120	COG3391	DNA-binding beta-propeller fold protein YncE	381
644376491	389	19.06	17	354	1	351	2.0e-06	47	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
644376492	590	28.31	41	588	152	752	1.0e-112	401	COG4993	Glucose dehydrogenase	773
644376493	106	41.3	15	106	15	106	4.0e-16	76.7	COG4654	Cytochrome c551/c552	110
644376494	217	39.13	5	211	3	203	1.0e-41	162	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644376495	529	31.59	182	526	66	407	3.0e-47	183	COG0840	Methyl-accepting chemotaxis protein	408
644376496	415	33.89	1	411	4	370	4.0e-82	298	COG2821	Membrane-bound lytic murein transglycosylase	373
644376497	365	28.21	23	365	22	371	2.0e-21	97.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644376498	1040	38	2	1020	1	1009	0.0e+00	883	COG0841	Multidrug efflux pump subunit AcrB	1009
644376499	224	25.46	12	223	7	199	1.0e-08	53.5	COG3637	Opacity protein and related surface antigens	199
644376500	195	46.59	6	179	1	176	2.0e-43	168	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
644376501	236	38.98	5	236	6	236	8.0e-48	183	COG2872	Ser-tRNA(Ala) deacylase AlaX (editing enzyme)	241
644376502	211	32.49	12	205	10	206	8.0e-10	57.2	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644376503	151	38.89	1	138	4	147	3.0e-28	117	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644376505	208	50.24	1	204	1	205	6.0e-67	247	COG0572	Uridine kinase	218
644376506	217	28.71	17	211	9	208	3.0e-21	95.3	COG0625	Glutathione S-transferase	211
644376507	64	67.74	1	62	1	62	2.0e-20	90.8	COG2975	Fe-S-cluster formation regulator IscX/YfhJ	64
644376508	113	42.99	1	105	1	102	6.0e-16	75.9	COG0633	Ferredoxin	102
644376509	619	43.96	18	605	4	579	0.0e+00	517	COG0443	Molecular chaperone DnaK (HSP70)	579
644376510	177	37.79	7	176	1	171	6.0e-19	87.3	COG1076	DnaJ-domain-containing proteins 1	174
644376511	107	52.78	1	107	3	110	1.0e-35	141	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
644376512	127	55.86	1	126	5	146	5.0e-38	149	COG0822	NifU homolog involved in Fe-S cluster formation	150
644376513	405	63.5	6	389	1	386	0.0e+00	574	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
644376514	160	42.36	1	143	1	144	3.0e-39	154	COG1959	DNA-binding transcriptional regulator, IscR family	150
644376515	373	28.19	38	371	3	321	5.0e-66	245	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
644376516	310	25.75	2	296	1	294	8.0e-30	124	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376517	530	35.14	7	530	21	553	8.0e-96	344	COG0747	ABC-type transport system, periplasmic component	556
644376518	342	50.29	1	342	1	317	7.0e-95	340	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644376519	307	50.18	22	305	9	288	2.0e-71	262	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644376520	323	56.6	3	317	1	315	2.0e-119	422	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
644376521	323	47.25	1	309	1	264	5.0e-99	354	COG4608	ABC-type oligopeptide transport system, ATPase component	309
644376522	175	44.38	13	172	3	158	9.0e-50	189	COG0669	Phosphopantetheine adenylyltransferase	159
644376523	329	38.84	11	327	65	387	4.0e-80	291	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
644376524	271	52.22	1	269	14	283	4.0e-90	324	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
644376525	262	47.69	2	259	1	257	3.0e-57	215	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
644376526	210	23.5	9	204	11	207	1.0e-13	69.9	COG1584	Succinate-acetate transporter protein	207
644376527	238	45.54	16	227	14	225	2.0e-68	252	COG1136	ABC-type lipoprotein export system, ATPase component	226
644376528	414	28.05	1	413	3	408	4.0e-61	229	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
644376529	355	29.04	38	346	36	369	1.0e-26	114	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644376530	106	41.9	1	103	2	106	2.0e-20	90.4	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
644376531	119	46.79	9	117	1	109	1.0e-28	118	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
644376532	149	46.1	2	141	1	140	6.0e-33	133	COG0822	NifU homolog involved in Fe-S cluster formation	150
644376533	420	56.33	18	417	3	404	0.0e+00	488	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
644376534	438	29.14	22	422	10	403	4.0e-69	255	COG0719	Fe-S cluster assembly scaffold protein SufB	412
644376535	255	60.32	1	251	3	250	8.0e-95	340	COG0396	Fe-S cluster assembly ATPase SufC	251
644376536	482	42.41	37	480	1	412	1.0e-122	433	COG0719	Fe-S cluster assembly scaffold protein SufB	412
644376537	156	33.33	2	141	1	141	5.0e-27	113	COG1959	DNA-binding transcriptional regulator, IscR family	150
644376539	313	35.55	3	299	2	296	3.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376541	686	26.16	1	678	2	670	1.0e-57	217	COG1289	Uncharacterized membrane protein YccC	674
644376543	303	39.04	2	285	8	337	5.0e-60	224	COG1566	Multidrug resistance efflux pump	352
644376544	476	34.83	55	474	31	450	4.0e-49	189	COG1538	Outer membrane protein TolC	457
644376547	577	33.15	22	567	143	687	1.0e-105	377	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
644376549	436	17.98	1	336	1	345	6.0e-12	65.9	COG0644	Dehydrogenase (flavoprotein)	396
644376550	497	49.69	20	496	2	468	0.0e+00	502	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644376552	476	25.51	112	442	18	346	3.0e-39	156	COG0641	Sulfatase maturation enzyme AslB, radical SAM superfamily	378
644376555	551	36.04	26	544	6	527	0.0e+00	467	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
644376556	301	26.94	8	301	2	294	1.0e-29	124	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376557	324	39.86	34	313	21	299	4.0e-54	205	COG0010	Arginase family enzyme	305
644376558	502	48.85	26	502	1	470	0.0e+00	505	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644376559	501	25.27	21	483	8	440	4.0e-45	176	COG1457	Purine-cytosine permease or related protein	442
644376560	561	51.19	1	536	4	542	0.0e+00	505	COG2303	Choline dehydrogenase or related flavoprotein	542
644376561	631	44.89	1	468	1	446	4.0e-114	405	COG3276	Selenocysteine-specific translation elongation factor	447
644376562	474	54.97	76	456	14	384	2.0e-108	386	COG1921	Seryl-tRNA(Sec) selenium transferase	395
644376563	307	49.51	1	305	1	304	1.0e-78	286	COG3058	Formate dehydrogenase maturation protein FdhE	308
644376564	212	60.28	1	211	1	214	1.0e-58	219	COG2864	Cytochrome b subunit of formate dehydrogenase	218
644376565	291	41.28	19	236	2	202	1.0e-56	213	COG0437	Fe-S-cluster-containing dehydrogenase component	203
644376568	164	49.07	1	161	1	161	9.0e-41	159	COG4119	Predicted NTP pyrophosphohydrolase, NUDIX family	161
644376569	517	24.68	42	353	36	346	4.0e-17	83.3	COG2814	Predicted arabinose efflux permease, MFS family	394
644376570	164	31.4	40	159	7	125	6.0e-12	63.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
644376571	256	33.59	4	256	15	270	1.0e-43	169	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644376572	402	49.87	12	394	6	389	9.0e-127	447	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
644376573	298	30.07	1	295	1	292	4.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376574	1145	62.6	2	1145	5	1148	0.0e+00	1707	COG1038	Pyruvate carboxylase	1149
644376575	287	35.71	1	276	13	290	6.0e-57	214	COG0685	5,10-methylenetetrahydrofolate reductase	291
644376576	324	62.01	17	324	1	306	0.0e+00	468	COG0320	Lipoate synthase	306
644376577	374	45.17	3	373	1	376	1.0e-101	363	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
644376578	418	67.72	5	416	4	412	0.0e+00	678	COG0112	Glycine/serine hydroxymethyltransferase	413
644376579	954	58.88	7	440	1	445	0.0e+00	618	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
644376579	954	65.05	464	920	25	493	0.0e+00	730	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
644376580	124	47.2	1	124	6	130	7.0e-37	145	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
644376582	1125	43.36	862	1117	1	255	7.0e-74	272	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644376583	156	51.55	1	156	1	160	1.0e-45	175	COG2135	Putative SOS response-associated peptidase YedK	226
644376585	178	22.16	2	169	12	180	9.0e-06	43.4	COG2801	Transposase InsO and inactivated derivatives	232
644376586	422	47.68	49	415	20	376	4.0e-91	328	COG3328	Transposase (or an inactivated derivative)	379
644376590	198	27.5	45	197	26	185	1.0e-27	116	COG2930	Lipid-binding SYLF domain	227
644376592	397	37.4	10	255	44	289	6.0e-69	254	COG1398	Fatty-acid desaturase	289
644376594	74	26.98	1	63	3	65	7.0e-07	45.7	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
644376597	350	26.78	1	349	10	347	2.0e-27	117	COG0628	Predicted PurR-regulated permease PerM	355
644376598	249	24.64	8	211	3	213	1.0e-21	96.8	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
644376599	305	27.76	3	296	4	296	5.0e-39	155	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376600	433	19.36	7	425	20	441	2.0e-17	84.5	COG2271	Sugar phosphate permease	448
644376603	202	48.63	1	180	1	177	1.0e-55	209	COG1838	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain	184
644376604	542	28.06	151	542	20	408	4.0e-40	159	COG0840	Methyl-accepting chemotaxis protein	408
644376605	282	39.34	13	277	2	262	2.0e-61	229	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
644376608	272	22.02	20	269	9	282	1.0e-18	87.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644376609	265	61	1	259	4	259	9.0e-98	349	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
644376610	67	44.62	3	67	4	68	2.0e-12	64.1	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
644376611	301	31.79	1	274	1	270	3.0e-40	159	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644376612	233	37.68	19	223	7	205	5.0e-44	171	COG2945	Alpha/beta superfamily hydrolase	210
644376614	492	49.17	4	483	1	471	0.0e+00	525	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644376616	178	31.29	15	176	10	167	2.0e-25	108	COG4032	Sulfopyruvate decarboxylase, TPP-binding subunit (coenzyme M biosynthesis)	172
644376617	316	37.21	1	299	1	297	3.0e-36	146	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376618	300	32.77	7	298	3	292	2.0e-31	129	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376619	222	35.24	7	215	11	210	1.0e-36	146	COG0684	Regulator of RNase E activity RraA	210
644376620	220	35.75	1	207	3	202	5.0e-38	151	COG0684	Regulator of RNase E activity RraA	210
644376621	216	36.87	13	209	9	205	2.0e-37	149	COG0684	Regulator of RNase E activity RraA	210
644376622	402	42.82	10	402	3	393	1.0e-110	393	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
644376624	128	26.24	7	125	3	138	4.0e-08	50.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644376625	254	34.29	10	251	8	251	2.0e-14	73.1	COG0730	Uncharacterized membrane protein YfcA	258
644376626	289	31.51	1	287	1	289	3.0e-33	135	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376627	353	39.44	30	348	6	324	1.0e-78	287	COG1171	Threonine dehydratase	347
644376628	152	25.87	6	148	1	125	3.0e-14	71.5	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
644376629	301	32.86	1	274	1	270	7.0e-36	144	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644376630	264	36.65	39	259	14	222	6.0e-52	197	COG0765	ABC-type amino acid transport system, permease component	222
644376631	221	40.55	5	221	10	220	2.0e-44	172	COG0765	ABC-type amino acid transport system, permease component	222
644376632	245	64.32	3	243	1	240	4.0e-108	384	COG1126	ABC-type polar amino acid transport system, ATPase component	240
644376633	306	25.6	4	287	1	289	5.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376634	204	31.53	4	203	3	205	1.0e-21	96.5	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644376635	1145	62.34	2	1145	5	1148	0.0e+00	1713	COG1038	Pyruvate carboxylase	1149
644376637	245	34.47	1	185	2	207	2.0e-29	122	COG0778	Nitroreductase	207
644376638	303	32.76	3	293	1	289	4.0e-33	135	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376639	284	41.22	8	282	6	272	3.0e-69	255	COG3777	Hydroxyacyl-ACP dehydratase HTD2, hotdog domain	273
644376640	385	37.28	1	385	3	393	1.0e-83	304	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644376641	392	44.67	1	392	5	396	7.0e-114	404	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
644376642	277	42.29	13	277	1	277	7.0e-50	190	COG2301	Citrate lyase beta subunit	283
644376643	331	38.84	2	327	4	329	2.0e-89	322	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
644376644	249	51.15	1	249	1	260	1.0e-67	249	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
644376645	312	56.29	1	311	1	312	4.0e-84	305	COG2025	Electron transfer flavoprotein, alpha subunit	313
644376646	545	32.89	6	458	1	396	8.0e-80	291	COG0644	Dehydrogenase (flavoprotein)	396
644376648	317	32.9	15	316	25	330	1.0e-51	197	COG1171	Threonine dehydratase	347
644376649	128	43.8	6	123	9	129	9.0e-26	108	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
644376650	253	32.89	18	240	2	217	8.0e-35	140	COG2964	Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains	220
644376652	220	26.81	57	194	25	143	1.0e-15	76.5	COG0262	Dihydrofolate reductase	167
644376653	151	62.5	1	144	1	143	1.0e-57	215	COG4275	Uncharacterized protein	143
644376655	199	31	1	194	2	200	9.0e-30	123	COG0605	Superoxide dismutase	204
644376656	396	35.56	14	192	3	182	6.0e-32	131	COG2059	Chromate transport protein ChrA	195
644376657	317	41.13	182	317	3	142	3.0e-35	142	COG4275	Uncharacterized protein	143
644376658	89	28.75	10	89	11	88	2.0e-13	67.2	COG1937	DNA-binding transcriptional regulator, FrmR family	89
644376659	349	24.73	11	289	8	290	4.0e-14	72.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
644376662	272	35.16	2	269	1	263	3.0e-35	142	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644376663	247	41.25	7	246	10	222	6.0e-52	197	COG0765	ABC-type amino acid transport system, permease component	222
644376664	861	56.94	7	847	5	804	0.0e+00	1055	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
644376665	155	23.02	17	142	14	136	2.0e-15	75.1	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
644376666	148	21.95	23	145	17	137	5.0e-15	73.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
644376667	362	52.6	1	362	3	365	0.0e+00	477	COG1932	Phosphoserine aminotransferase	365
644376668	402	21.35	30	385	36	382	8.0e-14	71.8	COG2814	Predicted arabinose efflux permease, MFS family	394
644376670	196	37.65	37	193	46	206	6.0e-30	123	COG4122	Predicted O-methyltransferase YrrM	219
644376671	357	50.36	85	357	1	277	4.0e-92	331	COG0077	Prephenate dehydratase	279
644376672	195	37.44	1	191	12	205	2.0e-42	165	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
644376673	226	40.1	3	204	2	196	1.0e-43	169	COG3155	Enhancing lycopene biosynthesis protein 2	217
644376674	338	61.43	58	336	8	286	1.0e-101	363	COG2876	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	286
644376675	148	26.83	15	135	11	129	4.0e-11	60.8	COG1765	Uncharacterized OsmC-related protein	137
644376677	214	30.84	4	210	7	216	7.0e-28	117	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
644376678	276	55.47	3	276	1	272	6.0e-98	350	COG0253	Diaminopimelate epimerase	272
644376679	194	22.75	1	189	3	189	7.0e-11	60.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644376681	270	36.4	1	261	2	251	3.0e-48	185	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
644376682	410	38.27	37	387	3	357	6.0e-62	231	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
644376683	362	46.01	15	339	3	320	3.0e-108	385	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
644376686	365	52.45	1	365	3	370	7.0e-103	367	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
644376687	445	33.6	170	418	23	273	3.0e-33	136	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
644376688	406	43.72	15	405	7	400	3.0e-119	422	COG0162	Tyrosyl-tRNA synthetase	401
644376689	340	29.1	20	331	2	312	3.0e-38	152	COG4255	Uncharacterized protein	318
644376690	571	41.72	35	531	1	477	9.0e-108	384	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
644376692	531	36.84	95	531	11	436	1.0e-77	284	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
644376694	459	44.88	7	454	4	433	2.0e-108	386	COG1030	Membrane-bound serine protease (ClpP class)	436
644376695	257	44.02	8	209	7	215	1.0e-39	156	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
644376696	592	38.29	42	587	4	528	0.0e+00	509	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
644376697	348	45.87	16	339	15	341	2.0e-92	332	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
644376698	324	49.53	4	322	2	322	8.0e-114	403	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
644376699	150	24.29	1	137	2	130	4.0e-08	51.1	COG3871	General stress protein 26 (function unknown)	145
644376700	363	33.83	1	363	2	401	3.0e-66	246	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
644376702	914	31.64	93	645	7	528	8.0e-85	308	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644376703	287	35.47	6	285	1	294	1.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376704	404	38.3	16	403	9	395	5.0e-67	248	COG2807	Cyanate permease	395
644376705	255	32.82	4	255	13	268	2.0e-38	152	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644376706	399	25.88	7	390	12	399	6.0e-38	151	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
644376709	119	42.34	9	119	1	103	2.0e-20	91.4	COG0023	Translation initiation factor 1 (eIF-1/SUI1)	104
644376710	602	70.27	1	602	1	602	0.0e+00	1015	COG1217	Predicted membrane GTPase involved in stress response	603
644376712	331	43.33	3	323	1	325	6.0e-66	244	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
644376713	832	41.43	91	808	1	712	0.0e+00	663	COG2217	Cation transport ATPase	713
644376714	63	47.27	1	55	1	55	4.0e-12	63	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
644376715	901	41.34	38	887	44	915	0.0e+00	742	COG0474	Magnesium-transporting ATPase (P-type)	917
644376717	574	46.7	390	570	1	181	2.0e-43	171	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644376718	344	28.48	8	303	15	310	3.0e-42	166	COG0687	Spermidine/putrescine-binding periplasmic protein	363
644376720	463	32.6	7	454	6	454	6.0e-89	321	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
644376721	243	62.87	2	163	1	165	8.0e-65	240	COG0678	Peroxiredoxin	165
644376722	130	25.9	5	127	2	138	2.0e-10	58.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644376723	625	26.9	324	608	3	287	1.0e-26	115	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
644376724	315	28.29	5	255	2	244	1.0e-24	107	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
644376725	408	35.43	1	375	23	392	3.0e-74	272	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
644376726	371	48.4	9	371	8	376	8.0e-100	357	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
644376727	408	23.43	95	407	10	334	1.0e-21	97.8	COG3240	Phospholipase/lecithinase/hemolysin	370
644376728	652	52.35	23	633	1	596	0.0e+00	663	COG0465	ATP-dependent Zn proteases	596
644376729	264	36.88	9	259	2	257	5.0e-46	178	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
644376732	302	36.05	10	264	1	243	2.0e-50	192	COG1360	Flagellar motor protein MotB	244
644376733	286	44.56	1	285	3	266	1.0e-68	253	COG1291	Flagellar motor component MotA	266
644376734	473	22.65	54	462	4	405	2.0e-29	124	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
644376735	459	41.63	6	454	1	449	0.0e+00	510	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
644376736	444	37.77	1	441	2	441	2.0e-112	399	COG0174	Glutamine synthetase	443
644376737	252	43.43	1	247	1	243	2.0e-66	245	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
644376738	374	66.04	1	371	1	371	0.0e+00	527	COG0686	Alanine dehydrogenase	371
644376739	180	35.48	6	67	5	66	1.0e-09	56.4	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
644376740	496	48.23	20	496	2	469	0.0e+00	484	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644376741	161	58.64	1	161	4	165	4.0e-51	193	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
644376743	213	44.5	4	212	2	208	2.0e-31	128	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644376746	202	28.57	10	145	4	142	1.0e-13	69.6	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
644376747	104	42.16	1	100	9	110	2.0e-20	90.7	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
644376751	67	59.7	1	67	1	67	4.0e-24	102	COG1278	Cold shock protein, CspA family	67
644376752	188	59.14	1	180	1	186	5.0e-63	233	COG3310	Uncharacterized protein	196
644376755	287	41.56	49	286	3	236	1.0e-51	196	COG0412	Dienelactone hydrolase	236
644376757	149	36.91	1	145	4	151	2.0e-18	85.4	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
644376758	148	24.81	9	139	1	131	2.0e-12	64.9	COG0824	Acyl-CoA thioesterase FadM	137
644376760	323	56.83	38	311	22	297	9.0e-97	346	COG4973	Site-specific recombinase XerC	299
644376761	166	55.06	4	161	6	162	5.0e-46	176	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
644376762	549	49.59	48	537	1	446	0.0e+00	510	COG0166	Glucose-6-phosphate isomerase	446
644376763	181	65.19	1	181	1	181	2.0e-82	298	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
644376764	415	26.01	125	411	12	294	4.0e-21	96.1	COG0501	Zn-dependent protease with chaperone function	302
644376765	109	47.78	17	104	6	95	4.0e-24	103	COG2154	Pterin-4a-carbinolamine dehydratase	101
644376766	290	39.1	2	286	12	293	6.0e-78	284	COG1162	Putative ribosome biogenesis GTPase RsgA	301
644376767	245	39.44	1	242	3	250	1.0e-47	183	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644376768	169	51.32	10	160	10	160	3.0e-48	184	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
644376770	393	24.27	61	369	25	281	7.0e-15	75.2	COG4974	Site-specific recombinase XerD	300
644376772	379	44.6	16	376	8	341	4.0e-79	288	COG1566	Multidrug resistance efflux pump	352
644376773	471	35.18	19	470	1	448	2.0e-50	193	COG1538	Outer membrane protein TolC	457
644376774	205	25.25	4	201	9	200	4.0e-13	68.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644376775	212	27.04	1	196	2	189	6.0e-13	67.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644376776	394	38.16	8	383	6	371	1.0e-31	131	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644376777	1069	53.39	1	1027	2	1009	0.0e+00	1068	COG0841	Multidrug efflux pump subunit AcrB	1009
644376778	488	42.27	12	470	1	446	2.0e-69	257	COG1538	Outer membrane protein TolC	457
644376779	206	32.24	61	206	36	187	1.0e-09	56.6	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
644376780	624	35.1	1	598	1	515	2.0e-109	390	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
644376781	319	27.47	1	270	4	266	3.0e-24	106	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
644376786	66	55.77	14	65	5	56	4.0e-08	49.5	COG3847	Flp pilus assembly protein, pilin Flp	58
644376787	183	29.75	17	173	11	153	3.0e-07	48.7	COG4960	Flp pilus assembly protein, protease CpaA	168
644376789	282	36.27	1	267	9	274	2.0e-42	165	COG3745	Flp pilus assembly protein CpaB	276
644376790	520	36.92	33	489	2	431	7.0e-80	291	COG4964	Flp pilus assembly protein, secretin CpaC	455
644376793	156	21.43	2	148	14	164	4.0e-07	47.4	COG4961	Flp pilus assembly protein TadG	185
644376794	415	25.29	51	389	32	361	3.0e-43	169	COG4963	Flp pilus assembly protein, ATPase CpaE	366
644376795	452	56.42	52	409	1	353	1.0e-120	426	COG4962	Pilus assembly protein, ATPase of CpaF family	355
644376796	324	31.66	6	324	1	309	1.0e-51	197	COG4965	Flp pilus assembly protein TadB	309
644376797	314	37.18	73	302	82	314	5.0e-23	101	COG2064	Pilus assembly protein TadC	320
644376799	358	33.79	6	358	9	368	7.0e-61	227	COG0387	Ca2+/H+ antiporter	368
644376801	165	42.86	1	159	1	159	3.0e-28	117	COG1267	Phosphatidylglycerophosphatase A	160
644376802	316	45	1	315	3	317	3.0e-79	288	COG0611	Thiamine monophosphate kinase	317
644376803	148	44.52	1	140	6	151	4.0e-32	130	COG0781	Transcription termination factor NusB	151
644376804	155	42.11	5	152	1	152	2.0e-41	161	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
644376805	368	61.58	1	203	1	202	4.0e-81	295	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
644376806	203	45.59	1	203	1	197	2.0e-65	241	COG0307	Riboflavin synthase alpha chain	204
644376807	536	69.47	8	530	5	528	0.0e+00	861	COG4108	Peptide chain release factor RF-3	528
644376809	214	17.58	1	180	6	185	9.0e-10	57.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644376810	423	39.76	6	415	3	407	1.0e-92	333	COG2995	Uncharacterized paraquat-inducible protein A	418
644376811	528	42	2	526	23	551	5.0e-130	458	COG3008	Paraquat-inducible protein B	553
644376812	192	37.77	1	186	1	188	8.0e-27	113	COG3009	Uncharacterized lipoprotein YmbA	190
644376813	477	32.08	33	454	56	472	1.0e-84	307	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644376815	990	37.21	307	988	180	856	0.0e+00	481	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
644376816	297	34.93	8	296	6	293	1.0e-36	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376817	330	41.87	1	330	2	332	2.0e-87	316	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
644376818	311	26.78	3	291	1	289	2.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376819	217	16.99	13	209	1	205	3.0e-19	88.3	COG1335	Nicotinamidase-related amidase	205
644376820	616	43.33	1	536	3	534	0.0e+00	517	COG1574	Predicted amidohydrolase YtcJ	535
644376823	146	30.4	24	142	12	135	5.0e-06	43.8	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
644376824	234	30.33	16	225	11	212	5.0e-18	84.9	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
644376825	296	28.62	5	292	1	287	3.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376827	791	34.53	18	791	52	873	0.0e+00	482	COG3002	Uncharacterized conserved protein YbcC, UPF0753/DUF2309 family	880
644376828	320	42.45	1	206	1	211	3.0e-57	215	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
644376829	263	28.14	31	254	16	245	3.0e-41	162	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644376830	203	23.65	15	162	11	158	6.0e-10	57.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644376831	430	47.88	1	419	1	421	8.0e-117	413	COG2907	Predicted NAD/FAD-binding protein	447
644376832	258	34.82	6	249	9	253	5.0e-45	174	COG3496	Uncharacterized conserved protein, DUF1365 family	261
644376833	402	45.42	118	397	3	281	7.0e-78	284	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
644376835	260	25.29	14	259	5	261	6.0e-35	141	COG0300	Short-chain dehydrogenase	265
644376837	180	50.62	15	176	11	172	2.0e-48	185	COG3040	Bacterial lipocalin	174
644376839	145	41.61	5	138	1	137	1.0e-33	135	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
644376840	158	43.56	1	158	1	161	2.0e-31	128	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
644376841	142	36.92	9	136	3	131	2.0e-19	88.3	COG1917	Cupin domain protein related to quercetin dioxygenase	131
644376842	283	49.82	1	275	3	280	5.0e-99	354	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
644376844	382	37.02	1	382	1	384	2.0e-102	365	COG1979	Alcohol dehydrogenase YqhD, Fe-dependent ADH family	384
644376845	320	28.38	5	301	2	296	4.0e-32	132	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376846	346	37.97	1	344	4	336	2.0e-90	325	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
644376847	159	42.48	1	153	3	154	1.0e-30	125	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644376848	861	78.47	1	861	1	852	0.0e+00	1495	COG1049	Aconitase B	852
644376849	300	31.19	5	295	1	295	3.0e-38	152	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376850	935	55.23	10	935	4	861	0.0e+00	1120	COG1048	Aconitase A	861
644376851	184	56.98	1	179	1	178	1.0e-57	215	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
644376852	502	68.2	5	436	6	439	0.0e+00	535	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
644376853	361	58.95	1	358	1	363	0.0e+00	480	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
644376856	130	38.14	7	124	2	116	3.0e-23	100	COG3450	Predicted enzyme of the cupin superfamily	116
644376857	394	28.75	7	386	17	407	2.0e-65	243	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644376858	465	27.62	37	463	17	412	1.0e-59	224	COG0232	dGTP triphosphohydrolase	412
644376859	291	28.48	1	291	1	309	2.0e-26	113	COG0679	Predicted permease	311
644376860	215	36.82	7	207	3	202	9.0e-40	156	COG0406	Broad specificity phosphatase PhoE	208
644376861	131	61.11	4	128	1	126	2.0e-54	203	COG0229	Peptide methionine sulfoxide reductase MsrB	140
644376862	462	44.2	24	428	15	391	6.0e-94	338	COG2262	50S ribosomal subunit-associated GTPase HflX	411
644376863	417	45.5	1	417	34	452	2.0e-107	382	COG0513	Superfamily II DNA and RNA helicase	513
644376864	583	21.58	75	536	21	449	4.0e-25	110	COG0531	Amino acid transporter	466
644376865	198	40.96	1	187	10	197	1.0e-37	149	COG3548	Uncharacterized membrane protein	197
644376866	300	24.43	2	297	4	303	7.0e-48	184	COG0462	Phosphoribosylpyrophosphate synthetase	314
644376867	501	36.02	93	495	1	419	6.0e-95	341	COG0213	Thymidine phosphorylase	435
644376868	871	32.99	40	857	42	912	0.0e+00	598	COG0474	Magnesium-transporting ATPase (P-type)	917
644376869	497	23.48	213	475	1	233	9.0e-42	165	COG0775	Nucleoside phosphorylase	234
644376870	660	41.04	3	655	2	605	0.0e+00	549	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
644376871	524	23.29	13	518	10	536	7.0e-50	192	COG2303	Choline dehydrogenase or related flavoprotein	542
644376873	363	38.67	10	360	1	350	7.0e-76	277	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
644376875	191	25.68	23	167	1	137	8.0e-06	43.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644376879	345	53.5	9	337	1	320	1.0e-118	419	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
644376880	336	47.18	4	336	25	344	2.0e-95	342	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
644376881	573	44.77	124	572	8	445	1.0e-121	430	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
644376883	346	37.89	19	339	8	325	1.0e-80	293	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
644376885	381	34.48	192	364	3	176	6.0e-29	121	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644376886	218	50.95	1	210	39	247	3.0e-63	234	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644376887	246	47.01	8	241	4	226	3.0e-69	255	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
644376888	209	51.44	6	209	24	226	1.0e-55	209	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
644376890	216	31.03	23	195	5	178	3.0e-08	52	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644376891	315	33.33	10	311	1	297	1.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376892	142	35.57	1	142	4	151	2.0e-14	71.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
644376893	245	27.13	1	228	7	248	5.0e-33	134	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
644376894	128	44.63	10	127	3	123	1.0e-24	105	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
644376895	259	30.25	1	257	2	279	3.0e-21	95.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644376896	446	44.55	4	441	1	437	1.0e-114	406	COG0015	Adenylosuccinate lyase	438
644376897	400	43.2	1	400	1	392	6.0e-88	318	COG0183	Acetyl-CoA acetyltransferase	392
644376898	218	51.64	1	212	3	214	3.0e-67	248	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
644376899	263	56.56	38	258	1	219	1.0e-72	266	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
644376900	645	44.41	287	633	10	355	2.0e-108	387	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
644376901	277	32.02	1	248	1	252	4.0e-46	178	COG0169	Shikimate 5-dehydrogenase	283
644376902	151	58	2	151	1	144	4.0e-57	213	COG0757	3-dehydroquinate dehydratase	146
644376903	242	36.21	23	195	17	188	2.0e-31	128	COG2091	Phosphopantetheinyl transferase	223
644376904	338	48.16	38	332	4	300	7.0e-73	267	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
644376905	340	18.69	16	315	2	266	1.0e-10	61.1	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
644376906	857	34.24	50	675	1	642	4.0e-93	336	COG1020	Non-ribosomal peptide synthetase component F	642
644376908	337	29.14	12	323	8	322	2.0e-37	150	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
644376909	343	38.1	45	332	12	300	1.0e-68	253	COG0031	Cysteine synthase	300
644376910	138	29.46	8	135	4	129	1.0e-12	66	COG1917	Cupin domain protein related to quercetin dioxygenase	131
644376911	251	27.35	1	218	1	233	5.0e-20	91.5	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
644376912	145	41.73	17	141	46	172	2.0e-22	98.7	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
644376913	479	39.11	13	478	5	458	1.0e-105	377	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644376914	327	25.8	15	322	1	297	1.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
644376915	352	44.6	1	350	1	339	6.0e-93	334	COG3938	Proline racemase	341
644376916	312	29.06	1	309	4	320	3.0e-47	182	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
644376918	194	31.93	7	118	2	120	3.0e-08	51.9	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
644376919	176	41.82	6	170	3	167	2.0e-46	178	COG1247	L-amino acid N-acyltransferase YncA	169
644376920	146	30.87	1	145	1	148	7.0e-10	56.7	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
644376921	348	29.75	72	342	1	250	3.0e-38	152	COG0121	Predicted glutamine amidotransferase	252
644376922	463	27.78	6	452	9	440	3.0e-53	203	COG1457	Purine-cytosine permease or related protein	442
644376923	258	38.52	6	256	1	251	1.0e-40	160	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644376925	381	34.64	22	372	1	355	2.0e-58	219	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
644376926	345	21.45	69	341	1	230	7.0e-18	85.2	COG3039	Transposase and inactivated derivatives, IS5 family	230
644376927	409	20.22	54	405	43	394	2.0e-09	57.5	COG2814	Predicted arabinose efflux permease, MFS family	394
644376928	456	22.04	23	444	13	394	8.0e-18	85.3	COG2814	Predicted arabinose efflux permease, MFS family	394
644376929	292	37.74	2	253	1	256	2.0e-48	186	COG0169	Shikimate 5-dehydrogenase	283
644376930	361	22.16	4	345	3	348	1.0e-23	104	COG3203	Outer membrane protein (porin)	354
644376931	288	36.33	44	287	1	244	6.0e-53	201	COG1414	DNA-binding transcriptional regulator, IclR family	246
644376933	346	50.44	4	346	6	346	4.0e-103	368	COG0709	Selenophosphate synthase	346
644376934	346	30.84	10	329	11	301	9.0e-34	137	COG2603	tRNA 2-selenouridine synthase SelU, contains rhodanese domain	334
644376935	659	39.67	4	236	8	246	1.0e-62	235	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
644376936	141	29.85	10	140	7	137	3.0e-23	101	COG0824	Acyl-CoA thioesterase FadM	137
644376937	334	34.85	10	334	7	335	4.0e-63	235	COG3938	Proline racemase	341
644376938	381	35.01	23	371	1	354	2.0e-56	213	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
644376939	420	26.98	5	420	1	381	7.0e-36	145	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644376940	523	27.4	6	494	2	466	7.0e-56	212	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644376941	315	27.27	2	305	1	297	4.0e-50	192	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
644376942	308	39.21	1	308	4	332	4.0e-86	311	COG3938	Proline racemase	341
644376944	257	30.31	5	257	10	252	2.0e-11	62.7	COG0730	Uncharacterized membrane protein YfcA	258
644376946	222	47.64	6	217	1	208	3.0e-53	201	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644376947	645	27.73	16	645	4	574	2.0e-101	363	COG3850	Signal transduction histidine kinase, nitrate/nitrite-specific	574
644376948	215	30.95	1	206	1	205	3.0e-39	155	COG0288	Carbonic anhydrase	207
644376949	324	47.24	1	324	1	322	3.0e-96	345	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
644376950	656	30.57	269	654	27	408	3.0e-43	170	COG0840	Methyl-accepting chemotaxis protein	408
644376951	674	35.01	23	655	42	665	1.0e-117	417	COG4389	Site-specific recombinase	677
644376952	228	47.11	4	227	2	224	1.0e-52	199	COG2181	Nitrate reductase gamma subunit	228
644376953	213	45.51	1	166	4	170	7.0e-37	147	COG2180	Nitrate reductase assembly protein NarJ, required for insertion of molybdenum cofactor	179
644376954	516	71.6	1	498	1	500	0.0e+00	887	COG1140	Nitrate reductase beta subunit	513
644376955	1228	70.3	1	1221	1	1227	0.0e+00	2062	COG5013	Nitrate reductase alpha subunit	1227
644376956	460	40.18	14	454	1	404	4.0e-88	319	COG2223	Nitrate/nitrite transporter NarK	417
644376957	418	37.89	7	416	11	416	8.0e-89	321	COG2223	Nitrate/nitrite transporter NarK	417
644376958	229	25.47	9	217	1	212	1.0e-27	116	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
644376960	394	33.91	26	370	19	347	2.0e-50	193	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
644376963	207	36.23	2	204	1	204	6.0e-29	120	COG0625	Glutathione S-transferase	211
644376965	325	21.71	171	320	6	148	9.0e-14	71.2	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644376966	344	20.92	179	330	1	145	3.0e-11	62.8	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644376969	103	45.26	10	103	11	105	7.0e-17	78.6	COG4654	Cytochrome c551/c552	110
644376970	573	21.24	54	162	38	147	2.0e-07	51.1	COG2010	Cytochrome c, mono- and diheme variants	150
644376971	611	34.32	1	611	7	637	3.0e-109	389	COG4548	Nitric oxide reductase activation protein	637
644376973	268	26.72	11	260	20	274	2.0e-29	122	COG0714	MoxR-like ATPase	329
644376975	196	31.18	9	194	22	205	2.0e-27	115	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
644376978	279	56.02	28	268	3	241	9.0e-76	277	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
644376979	418	67.72	5	416	4	412	0.0e+00	679	COG0112	Glycine/serine hydroxymethyltransferase	413
644376980	466	50	174	455	1	262	7.0e-90	324	COG1760	L-serine deaminase	262
644376981	214	51.43	34	207	1	174	6.0e-60	223	COG0225	Peptide methionine sulfoxide reductase MsrA	174
644376982	583	30.14	1	212	10	217	4.0e-22	100	COG0785	Cytochrome c biogenesis protein CcdA	220
644376983	185	50.78	57	183	4	131	2.0e-52	198	COG0229	Peptide methionine sulfoxide reductase MsrB	140
644376984	452	19	19	436	2	387	2.0e-16	80.6	COG2814	Predicted arabinose efflux permease, MFS family	394
644376985	312	38.87	1	299	3	302	3.0e-80	291	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
644376986	327	48.16	1	325	2	327	4.0e-96	344	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
644376987	290	59.34	16	288	11	283	2.0e-93	335	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
644376988	392	51.43	5	384	4	383	1.0e-124	440	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
644376989	367	36.27	24	307	7	266	3.0e-64	239	COG1018	Ferredoxin-NADP reductase	266
644376990	419	31.58	26	419	4	361	1.0e-67	250	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
644376991	257	26.42	5	256	14	260	7.0e-13	68	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
644376992	375	34.18	61	363	4	312	2.0e-50	193	COG2025	Electron transfer flavoprotein, alpha subunit	313
644376993	633	28.43	237	632	2	386	1.0e-61	231	COG0247	Fe-S oxidoreductase	388
644376994	686	41.78	1	368	1	363	4.0e-101	362	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
644376998	251	35.02	9	244	18	232	4.0e-16	78.9	COG2801	Transposase InsO and inactivated derivatives	232
644377000	679	21.14	433	675	60	266	3.0e-10	60.9	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
644377002	459	34.85	117	423	1	273	6.0e-38	152	COG4253	Uncharacterized conserved protein, DUF2345 family	278
644377006	255	33.33	5	255	17	270	2.0e-40	159	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644377007	628	43.02	1	355	1	350	4.0e-85	309	COG3457	Predicted amino acid racemase	353
644377008	158	38.06	1	152	1	155	2.0e-37	148	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
644377009	496	48.39	5	496	5	497	0.0e+00	616	COG2317	Zn-dependent carboxypeptidase, M32 family	497
644377011	346	40.39	1	255	4	250	5.0e-56	211	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
644377012	364	69.66	3	147	2	146	4.0e-57	215	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
644377013	151	56.67	1	150	1	150	1.0e-50	191	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
644377014	416	68.93	4	413	3	412	0.0e+00	653	COG0112	Glycine/serine hydroxymethyltransferase	413
644377018	618	54.37	1	615	8	575	0.0e+00	783	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
644377019	283	47.35	1	276	5	272	2.0e-67	249	COG0682	Prolipoprotein diacylglyceryltransferase	287
644377020	282	37.15	3	280	10	296	2.0e-55	209	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
644377021	267	38.98	1	253	2	254	8.0e-64	237	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
644377022	530	39.93	256	522	9	281	2.0e-41	164	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
644377023	255	21.92	1	246	2	284	7.0e-17	81.3	COG1234	Ribonuclease BN, tRNA processing enzyme	292
644377025	784	53.8	71	783	2	710	0.0e+00	750	COG2217	Cation transport ATPase	713
644377026	357	43.62	60	357	29	322	6.0e-69	254	COG0598	Mg2+ and Co2+ transporter CorA	322
644377027	488	41.55	1	479	4	492	2.0e-118	419	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
644377028	234	40.43	4	233	8	236	2.0e-36	145	COG0704	Phosphate uptake regulator	240
644377029	219	51.56	3	219	2	226	1.0e-71	262	COG0120	Ribose 5-phosphate isomerase	227
644377030	158	66.45	2	156	1	155	6.0e-62	230	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
644377031	228	48.46	1	224	2	227	1.0e-61	229	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
644377032	242	38.36	1	229	13	240	1.0e-42	166	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
644377033	147	60.42	4	144	2	145	6.0e-50	189	COG0328	Ribonuclease HI	154
644377035	252	30.83	1	218	13	250	2.0e-18	86.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644377036	658	31.82	470	579	7	111	1.0e-08	55.6	COG1388	LysM repeat	124
644377037	150	60.96	1	146	1	145	5.0e-53	200	COG1490	D-Tyr-tRNAtyr deacylase	145
644377038	259	59.61	1	255	1	251	2.0e-93	335	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
644377039	524	29.33	183	523	71	408	4.0e-46	179	COG0840	Methyl-accepting chemotaxis protein	408
644377041	94	46.15	1	78	1	78	1.0e-20	91.4	COG1254	Acylphosphatase	92
644377043	702	40.48	1	572	1	558	0.0e+00	639	COG0143	Methionyl-tRNA synthetase	558
644377044	383	49.12	113	334	51	265	3.0e-57	216	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
644377045	579	33.25	2	381	3	388	2.0e-48	187	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
644377046	281	39.86	3	280	104	388	2.0e-69	256	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
644377049	245	38.15	1	245	5	253	2.0e-41	162	COG1484	DNA replication protein DnaC	254
644377050	452	24.19	6	280	2	268	5.0e-21	95.9	COG4584	Transposase	278
644377052	304	25.09	13	300	1	287	1.0e-27	117	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377053	340	48.81	3	334	2	329	0.0e+00	496	COG1087	UDP-glucose 4-epimerase	329
644377054	471	26.75	49	459	4	404	2.0e-34	140	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
644377055	366	58.08	2	359	1	364	0.0e+00	531	COG0082	Chorismate synthase	369
644377056	209	30.19	8	206	33	244	2.0e-28	119	COG3751	Proline 4-hydroxylase (includes Rps23 Pro-64 3,4-dihydroxylase Tpa1), contains SM-20 domain	252
644377057	318	54.67	32	317	1	289	4.0e-111	394	COG3129	23S rRNA A1618 N6-methylase RlmF	292
644377058	873	37.15	1	866	5	859	0.0e+00	617	COG0308	Aminopeptidase N	859
644377059	594	44.52	5	577	1	527	0.0e+00	494	COG3975	Predicted metalloprotease, contains C-terminal PDZ domain	558
644377060	475	75.63	2	473	6	481	0.0e+00	709	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
644377061	204	60.09	3	204	1	223	9.0e-88	316	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
644377063	304	27.7	89	228	5	149	9.0e-17	81.2	COG2010	Cytochrome c, mono- and diheme variants	150
644377064	483	36.55	39	431	1	367	9.0e-78	284	COG0348	Polyferredoxin	386
644377065	174	36.48	9	165	3	160	4.0e-30	124	COG3198	Uncharacterized protein	172
644377066	133	32.43	1	132	1	148	1.0e-10	59.3	COG3126	Uncharacterized lipoprotein YbaY	158
644377067	462	59.78	3	462	6	470	0.0e+00	655	COG3033	Tryptophanase	471
644377070	338	26.12	22	310	3	286	2.0e-23	103	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
644377072	270	23.53	1	259	1	251	5.0e-22	98.5	COG3394	Predicted glycoside hydrolase or deacetylase ChbG, UPF0249 family	257
644377073	229	35.89	2	194	78	286	2.0e-35	142	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644377074	162	44.52	1	154	2	156	2.0e-40	158	COG1607	Acyl-CoA hydrolase	157
644377075	594	38.53	1	583	1	567	3.0e-130	459	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
644377076	218	42.41	26	216	1	190	2.0e-38	152	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
644377077	296	31.54	1	295	1	294	3.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377078	147	23.58	6	127	16	137	1.0e-10	59.1	COG5608	LEA14-like dessication related protein	161
644377079	305	33.22	8	300	5	293	3.0e-30	125	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377080	253	27.49	1	249	4	253	4.0e-08	51.9	COG0730	Uncharacterized membrane protein YfcA	258
644377081	294	70.65	1	292	1	293	9.0e-122	429	COG0074	Succinyl-CoA synthetase, alpha subunit	293
644377082	389	60.15	1	388	1	386	0.0e+00	511	COG0045	Succinyl-CoA synthetase, beta subunit	387
644377083	477	46.79	1	467	1	454	0.0e+00	487	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
644377084	417	52.72	1	416	1	404	4.0e-112	398	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
644377085	942	57.02	2	940	1	906	0.0e+00	1271	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
644377086	429	54.48	29	429	1	390	0.0e+00	498	COG0372	Citrate synthase	390
644377087	82	37.8	1	82	7	88	3.0e-14	69.9	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
644377088	234	55.74	2	234	1	232	9.0e-82	296	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
644377089	588	52.77	5	574	4	562	0.0e+00	631	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
644377090	114	40	1	114	2	116	2.0e-16	77.9	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
644377091	124	40.16	3	124	1	127	1.0e-13	68.4	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
644377092	243	35	4	242	1	235	9.0e-38	150	COG2188	DNA-binding transcriptional regulator, GntR family	236
644377093	325	30.56	5	325	1	311	9.0e-65	240	COG0039	Malate/lactate dehydrogenase	313
644377094	349	65.69	112	349	1	239	1.0e-100	360	COG1186	Protein chain release factor B	239
644377095	500	59.6	1	500	1	501	0.0e+00	710	COG1190	Lysyl-tRNA synthetase (class II)	502
644377097	439	38.55	7	425	2	421	1.0e-82	300	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
644377098	233	58.72	1	231	9	242	3.0e-88	317	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
644377099	51	61.22	1	49	2	50	5.0e-09	52.9	COG0267	Ribosomal protein L33	50
644377100	77	67.53	1	76	1	77	2.0e-21	93.8	COG0227	Ribosomal protein L28	77
644377101	543	64.52	2	543	1	533	0.0e+00	880	COG0504	CTP synthase (UTP-ammonia lyase)	533
644377102	283	59.57	1	277	5	275	1.0e-119	423	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
644377103	427	68.78	1	426	1	423	0.0e+00	663	COG0148	Enolase	423
644377104	98	51.06	1	94	24	117	3.0e-20	90	COG2919	Cell division protein FtsB	117
644377106	105	46.94	3	100	2	99	3.0e-25	106	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
644377107	145	46.21	1	144	1	145	8.0e-45	172	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
644377108	148	55.78	1	147	6	151	7.0e-51	192	COG0691	tmRNA-binding protein	153
644377110	525	68.92	201	525	2	315	0.0e+00	540	COG0519	GMP synthase, PP-ATPase domain/subunit	315
644377111	104	41.35	1	104	1	104	8.0e-20	88.8	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
644377112	128	27.73	6	124	10	127	6.0e-11	59.9	COG5393	Uncharacterized membrane protein YqjE	131
644377114	242	58.5	92	237	6	152	1.0e-47	183	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
644377116	219	18.72	6	215	35	228	7.0e-11	61	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
644377117	476	59.21	1	476	1	478	0.0e+00	676	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
644377118	308	38.73	2	308	1	310	1.0e-65	243	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
644377119	263	31.21	1	247	11	291	1.0e-30	127	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
644377120	244	55.37	1	240	1	242	1.0e-81	296	COG3484	Predicted proteasome-type protease	255
644377122	553	30.58	142	553	1	408	6.0e-46	179	COG0840	Methyl-accepting chemotaxis protein	408
644377123	701	30.56	25	701	50	750	1.0e-89	324	COG4774	Outer membrane receptor for monomeric catechols	750
644377124	204	25.71	1	203	1	203	4.0e-18	84.9	COG0625	Glutathione S-transferase	211
644377126	298	30.98	5	293	1	297	1.0e-33	137	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377127	112	62.16	1	111	1	111	3.0e-27	113	COG3136	Uncharacterized membrane protein, GlpM family	111
644377128	128	32.23	3	123	4	117	1.0e-20	91.9	COG3189	Uncharacterized conserved protein YeaO, DUF488 family	117
644377129	111	57.55	6	110	3	108	2.0e-24	104	COG1742	Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily	109
644377130	115	34.48	1	115	2	115	7.0e-22	95.9	COG3791	Uncharacterized conserved protein	133
644377131	137	29.51	10	126	9	126	7.0e-10	56.4	COG3607	Predicted lactoylglutathione lyase	133
644377132	157	17.45	1	148	5	136	1.0e-13	69.2	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
644377133	167	49.36	6	159	5	151	4.0e-47	180	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
644377134	138	59.13	12	126	14	128	8.0e-43	165	COG5649	Uncharacterized protein	132
644377135	137	23.49	1	133	8	149	2.0e-12	65.5	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
644377136	508	48.22	1	306	2	297	1.0e-107	383	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
644377137	460	72.17	1	460	1	460	0.0e+00	770	COG0114	Fumarate hydratase class II	462
644377138	270	50.4	13	137	6	130	1.0e-31	130	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
644377141	223	57.08	1	219	2	220	2.0e-61	228	COG4149	ABC-type molybdate transport system, permease component	225
644377142	252	42.19	1	252	3	257	2.0e-52	199	COG0725	ABC-type molybdate transport system, periplasmic component	258
644377145	250	42.13	4	248	2	251	3.0e-43	168	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644377147	263	25.86	64	237	11	170	5.0e-27	115	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
644377150	855	32.54	21	839	41	917	0.0e+00	600	COG0474	Magnesium-transporting ATPase (P-type)	917
644377151	1015	31.46	31	539	9	458	5.0e-70	260	COG0277	FAD/FMN-containing dehydrogenase	459
644377152	294	30.82	8	294	1	291	1.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377155	201	23.04	1	191	4	188	1.0e-11	63.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644377156	246	30.58	1	186	2	207	3.0e-23	102	COG0778	Nitroreductase	207
644377157	368	44.18	1	365	1	359	2.0e-94	339	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
644377158	227	31.73	21	226	11	183	1.0e-20	93.7	COG0693	Putative intracellular protease/amidase	188
644377160	469	31.66	14	463	1	446	9.0e-85	307	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644377161	230	47.73	6	223	4	217	5.0e-69	254	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
644377162	341	34.45	118	220	11	127	4.0e-12	66.1	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
644377163	209	32.29	2	209	4	212	2.0e-40	158	COG0602	Organic radical activating enzyme	212
644377164	85	50	4	76	13	91	3.0e-11	59.8	COG5572	Uncharacterized membrane protein	104
644377165	278	42.38	7	270	3	270	7.0e-73	267	COG3220	Uncharacterized conserved protein, UPF0276 family	282
644377167	154	33.09	21	149	10	142	1.0e-07	49.2	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
644377168	283	51.71	77	281	6	210	4.0e-55	208	COG0560	Phosphoserine phosphatase	212
644377170	641	44.44	454	633	4	181	4.0e-41	163	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644377171	311	26.04	139	306	10	177	1.0e-11	64	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644377172	458	41.91	2	456	9	458	0.0e+00	462	COG0773	UDP-N-acetylmuramate-alanine ligase	459
644377173	465	25.57	27	465	1	423	1.0e-48	187	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
644377174	753	46.77	552	736	2	181	4.0e-47	183	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644377175	128	24.82	1	125	1	138	2.0e-12	64.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644377176	230	29.57	1	228	1	222	2.0e-35	142	COG1451	Predicted metal-dependent hydrolase	223
644377177	256	31.8	20	231	13	224	2.0e-28	120	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
644377178	180	37.22	1	180	5	181	8.0e-48	183	COG0241	Histidinol phosphatase or a related phosphatase	181
644377179	686	52.89	1	685	2	690	0.0e+00	779	COG0751	Glycyl-tRNA synthetase, beta subunit	691
644377181	296	76.01	1	296	4	298	0.0e+00	548	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
644377182	343	33.14	1	340	1	350	6.0e-79	288	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
644377183	399	47.56	5	392	3	388	6.0e-117	414	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
644377184	333	57.7	4	333	1	329	0.0e+00	496	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
644377186	444	31.34	12	408	15	432	5.0e-52	199	COG0038	H+/Cl- antiporter ClcA	443
644377187	465	55.53	1	452	4	454	0.0e+00	540	COG1113	L-asparagine transporter and related permeases	462
644377188	373	63.56	1	372	1	369	0.0e+00	507	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
644377189	638	60.56	1	605	4	579	0.0e+00	670	COG0443	Molecular chaperone DnaK (HSP70)	579
644377190	181	43.33	3	178	14	193	3.0e-33	134	COG0576	Molecular chaperone GrpE (heat shock protein)	193
644377191	432	72.12	1	431	1	433	0.0e+00	658	COG2224	Isocitrate lyase	433
644377192	465	30.92	12	461	1	456	8.0e-42	165	COG0531	Amino acid transporter	466
644377193	298	28.33	3	297	2	297	2.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377194	721	47.35	252	718	103	543	0.0e+00	523	COG2225	Malate synthase	545
644377195	322	52.8	1	322	4	322	7.0e-85	307	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
644377196	308	62.5	1	296	1	292	2.0e-81	296	COG4120	ABC-type uncharacterized transport system, permease component	293
644377197	264	63.88	1	263	1	263	2.0e-101	362	COG1101	ABC-type uncharacterized transport system, ATPase component	263
644377198	235	31.49	4	234	1	235	2.0e-26	112	COG3471	Predicted secreted (periplasmic) protein	235
644377199	203	31.34	1	195	1	198	9.0e-30	123	COG0625	Glutathione S-transferase	211
644377203	634	61.87	2	632	1	621	0.0e+00	814	COG0326	Molecular chaperone, HSP90 family	623
644377204	263	18.53	1	238	4	261	4.0e-08	52.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644377205	311	67.58	3	294	2	294	1.0e-122	432	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
644377206	167	43.21	7	165	3	159	5.0e-31	127	COG0597	Lipoprotein signal peptidase	167
644377207	927	49.16	4	919	2	931	0.0e+00	1163	COG0060	Isoleucyl-tRNA synthetase	933
644377208	311	46.55	16	303	17	303	3.0e-87	315	COG0196	FAD synthase	304
644377209	218	31.28	1	208	3	187	6.0e-23	101	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
644377210	174	41.67	1	166	3	165	2.0e-39	155	COG3749	Uncharacterized conserved protein, DUF934 family	167
644377211	552	37.3	1	547	1	510	0.0e+00	494	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
644377212	235	41.51	17	224	35	241	4.0e-52	198	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
644377213	313	28.57	1	299	1	294	2.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377214	246	40.94	1	245	1	251	2.0e-48	186	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644377215	542	41.88	1	540	3	528	0.0e+00	564	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644377216	291	52.72	1	291	4	297	3.0e-93	335	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
644377217	378	26.84	1	377	2	341	2.0e-52	200	COG3317	Uncharacterized lipoprotein	342
644377218	377	35.96	1	374	6	383	8.0e-76	277	COG2850	Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain	383
644377219	159	40.85	1	159	1	161	7.0e-34	136	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
644377221	270	47.84	1	268	1	276	4.0e-66	244	COG2890	Methylase of polypeptide chain release factors	280
644377222	480	42.12	38	480	5	448	4.0e-116	411	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
644377224	273	41.37	1	272	5	281	1.0e-66	246	COG0169	Shikimate 5-dehydrogenase	283
644377225	150	26.45	30	150	10	109	3.0e-12	64.6	COG0607	Rhodanese-related sulfurtransferase	110
644377226	472	51.47	1	472	1	443	0.0e+00	529	COG0174	Glutamine synthetase	443
644377228	349	47.58	3	347	7	354	1.0e-98	353	COG3852	Signal transduction histidine kinase, nitrogen specific	363
644377229	487	46.31	1	484	2	464	0.0e+00	514	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644377230	307	34	6	302	1	296	1.0e-33	137	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377231	760	58.61	423	753	1	329	2.0e-126	446	COG0620	Methionine synthase II (cobalamin-independent)	330
644377232	154	34.06	1	129	2	139	2.0e-22	98.4	COG2062	Phosphohistidine phosphatase SixA	163
644377233	238	46.88	13	236	6	228	9.0e-50	190	COG1346	Putative effector of murein hydrolase	230
644377234	118	35.96	1	114	7	120	4.0e-13	66.7	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
644377235	180	30.94	3	180	1	173	2.0e-19	88.5	COG3161	4-hydroxybenzoate synthetase (chorismate-pyruvate lyase)	174
644377236	289	45.14	1	287	2	289	6.0e-52	197	COG0382	4-hydroxybenzoate polyprenyltransferase	289
644377239	313	29.02	128	313	1	191	4.0e-27	115	COG0352	Thiamine monophosphate synthase	211
644377240	209	25.67	3	188	1	148	4.0e-14	71.5	COG0262	Dihydrofolate reductase	167
644377241	208	22.55	1	203	1	161	1.0e-13	70	COG0262	Dihydrofolate reductase	167
644377242	289	60.49	3	286	5	285	8.0e-100	356	COG2607	Predicted ATPase, AAA+ superfamily	287
644377243	222	31.65	1	218	5	203	1.0e-36	146	COG0560	Phosphoserine phosphatase	212
644377245	345	63.66	4	345	2	345	0.0e+00	497	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
644377246	211	58.67	2	194	1	196	2.0e-75	275	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
644377248	418	37.15	64	417	1	355	6.0e-71	261	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
644377249	460	29.5	23	448	12	441	1.0e-46	180	COG0038	H+/Cl- antiporter ClcA	443
644377250	106	66.35	1	104	2	105	2.0e-43	167	COG0278	Glutaredoxin-related protein	105
644377251	275	38.78	25	269	6	249	3.0e-52	198	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644377252	210	60.77	1	208	2	210	1.0e-78	285	COG0035	Uracil phosphoribosyltransferase	210
644377254	414	42.33	6	413	17	448	5.0e-82	298	COG2233	Xanthine/uracil permease	451
644377256	170	26.79	5	163	12	179	8.0e-13	66.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644377257	944	31.6	12	523	1	459	6.0e-62	233	COG0277	FAD/FMN-containing dehydrogenase	459
644377258	183	22.5	3	158	1	200	4.0e-10	58.3	COG1335	Nicotinamidase-related amidase	205
644377259	111	46.24	7	98	3	95	1.0e-20	91.3	COG4390	Uncharacterized protein	106
644377260	149	56.38	1	149	1	148	4.0e-41	160	COG0359	Ribosomal protein L9	148
644377261	75	67.16	3	69	9	75	1.0e-19	88	COG0238	Ribosomal protein S18	75
644377262	99	38	1	97	3	102	3.0e-16	76.5	COG2965	Primosomal replication protein N	103
644377263	125	52.25	2	111	1	111	1.0e-33	135	COG0360	Ribosomal protein S6	112
644377264	69	40.58	1	69	1	69	3.0e-11	60.4	COG2608	Copper chaperone CopZ	71
644377266	102	48.19	18	100	5	87	8.0e-21	91.8	COG1937	DNA-binding transcriptional regulator, FrmR family	89
644377267	499	35.78	44	499	7	450	5.0e-73	268	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
644377268	251	48.56	2	243	19	257	1.0e-66	246	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
644377270	1129	51.98	11	1129	8	1134	0.0e+00	1372	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
644377271	413	40.8	4	390	13	394	1.0e-93	336	COG0019	Diaminopimelate decarboxylase	394
644377272	307	31.56	3	299	1	297	3.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377273	260	27.88	57	240	3	204	3.0e-16	79.3	COG0288	Carbonic anhydrase	207
644377274	296	26.6	2	295	12	292	1.0e-08	54.1	COG5006	Threonine/homoserine efflux transporter RhtA	292
644377275	309	30.54	8	300	1	293	6.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377276	69	66.67	1	69	1	69	7.0e-21	92.3	COG3360	Flavin-binding protein dodecin	71
644377277	795	50.7	4	790	3	735	0.0e+00	751	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
644377278	273	45.45	5	273	4	272	2.0e-76	278	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
644377279	340	41.67	12	319	8	314	3.0e-84	305	COG0180	Tryptophanyl-tRNA synthetase	314
644377281	101	28.57	7	95	7	97	2.0e-10	57.7	COG1605	Chorismate mutase	101
644377282	258	30.66	1	258	1	266	1.0e-37	150	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
644377283	257	52.36	1	251	2	254	2.0e-84	305	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
644377284	126	53.04	12	126	4	117	1.0e-36	144	COG3215	Tfp pilus assembly protein PilZ	117
644377286	208	46.31	3	204	2	204	8.0e-58	216	COG0125	Thymidylate kinase	208
644377287	331	35.84	1	329	9	340	1.0e-93	336	COG1559	Cell division protein YceG, involved in septum cleavage	342
644377288	251	26.67	8	249	8	260	4.0e-23	101	COG3971	2-keto-4-pentenoate hydratase	264
644377292	107	51.4	1	107	3	109	3.0e-21	93.5	COG3784	Uncharacterized conserved protein YdbL, DUF1318 family	109
644377293	168	68.26	1	167	26	192	1.0e-64	238	COG3812	Uncharacterized protein	193
644377295	828	37.36	9	828	6	829	0.0e+00	562	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
644377296	221	65.05	15	218	21	226	3.0e-73	268	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
644377297	195	32.21	12	192	1	208	5.0e-20	91.1	COG2755	Lysophospholipase L1 or related esterase	216
644377298	189	35.68	1	189	1	185	3.0e-26	111	COG0693	Putative intracellular protease/amidase	188
644377299	205	50	1	201	1	194	2.0e-68	252	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
644377300	404	29.31	6	392	9	407	1.0e-56	214	COG2124	Cytochrome P450	411
644377301	600	63.38	1	595	1	585	0.0e+00	915	COG0173	Aspartyl-tRNA synthetase	585
644377302	207	50.25	8	203	6	201	2.0e-58	218	COG2928	Uncharacterized membrane protein	222
644377303	81	35.14	1	74	8	80	6.0e-16	75.5	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
644377304	258	51	8	258	4	254	2.0e-89	322	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
644377305	311	28.04	34	297	27	319	1.0e-45	177	COG0280	Phosphotransacetylase	327
644377306	384	39.54	6	384	4	394	5.0e-108	384	COG0282	Acetate kinase	396
644377307	359	46.86	121	355	81	315	1.0e-74	273	COG2829	Outer membrane phospholipase A	317
644377308	88	56.82	1	88	1	88	6.0e-10	55.7	COG0268	Ribosomal protein S20	88
644377309	510	54.58	1	509	7	518	2.0e-126	446	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
644377310	279	55.12	3	129	4	130	5.0e-46	178	COG2904	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, N-terminal domain	137
644377312	405	58.67	1	150	1	150	1.0e-59	223	COG1017	Hemoglobin-like flavoprotein	150
644377313	153	34.69	1	145	1	147	3.0e-25	107	COG1959	DNA-binding transcriptional regulator, IscR family	150
644377314	327	29.96	6	240	12	234	3.0e-27	115	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
644377315	469	39.81	28	458	7	415	1.0e-120	427	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
644377316	251	34.65	27	227	7	208	5.0e-35	141	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
644377317	316	35.46	16	284	13	286	5.0e-29	121	COG3782	Uncharacterized protein	289
644377318	254	48.95	10	248	2	239	3.0e-69	255	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
644377319	262	49.81	1	257	1	259	6.0e-77	280	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
644377322	255	46.37	5	252	9	256	3.0e-57	215	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
644377323	265	51.39	4	254	2	248	4.0e-92	331	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
644377324	624	44.06	15	617	1	603	0.0e+00	502	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
644377325	447	49.24	7	447	6	463	0.0e+00	497	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644377326	299	30.58	1	276	1	276	5.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377327	406	38.15	32	397	1	343	2.0e-76	280	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
644377328	497	41.16	6	484	3	472	2.0e-124	439	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644377330	447	44.22	16	447	9	445	0.0e+00	495	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
644377331	336	42.86	1	331	1	339	4.0e-58	218	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
644377332	447	46.19	2	437	1	446	1.0e-123	436	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
644377333	189	43.02	1	172	2	171	1.0e-46	178	COG1510	DNA-binding transcriptional regulator GbsR, MarR family	177
644377334	848	51.93	5	845	5	843	0.0e+00	940	COG0249	DNA mismatch repair ATPase MutS	843
644377336	600	44.87	10	583	5	575	0.0e+00	689	COG4579	Isocitrate dehydrogenase kinase/phosphatase	578
644377338	745	74.53	1	742	1	741	0.0e+00	1261	COG2838	Monomeric isocitrate dehydrogenase	744
644377339	414	65.91	21	414	15	406	0.0e+00	596	COG0538	Isocitrate dehydrogenase	407
644377340	67	59.09	1	66	1	66	1.0e-24	104	COG1278	Cold shock protein, CspA family	67
644377341	102	52.48	1	101	6	106	5.0e-31	125	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
644377342	759	45.74	1	751	1	786	0.0e+00	871	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
644377343	296	56.19	1	296	2	300	3.0e-99	354	COG4974	Site-specific recombinase XerD	300
644377344	155	36.42	1	154	1	168	6.0e-30	123	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
644377345	122	64.66	1	116	3	115	7.0e-39	152	COG0335	Ribosomal protein L19	115
644377346	256	56.1	1	245	1	240	3.0e-102	364	COG0336	tRNA G37 N-methylase TrmD	240
644377347	168	43.71	1	164	2	168	3.0e-46	178	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
644377348	82	62.2	1	82	1	81	1.0e-26	111	COG0228	Ribosomal protein S16	87
644377349	893	39.84	6	630	4	595	1.0e-119	425	COG1042	Acyl-CoA synthetase (NDP forming)	598
644377350	305	40	3	301	34	324	4.0e-81	294	COG0379	Quinolinate synthase	324
644377351	247	54.98	1	245	1	251	7.0e-86	310	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
644377352	222	47.78	22	222	5	206	9.0e-55	206	COG2518	Protein-L-isoaspartate O-methyltransferase	209
644377353	361	28.62	85	358	2	262	2.0e-29	123	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
644377354	316	38.89	1	315	18	341	5.0e-71	261	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
644377357	304	46.53	15	304	26	328	2.0e-63	236	COG0714	MoxR-like ATPase	329
644377358	319	46.45	15	316	4	309	3.0e-84	305	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
644377359	214	44.55	1	200	1	200	2.0e-41	162	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
644377360	119	33.9	1	117	2	119	1.0e-25	108	COG1539	Dihydroneopterin aldolase	121
644377362	128	34.68	5	128	8	128	8.0e-28	115	COG2346	Truncated hemoglobin YjbI	133
644377363	419	28.4	1	416	5	375	2.0e-35	143	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644377364	288	46.82	22	278	1	264	1.0e-70	260	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
644377365	116	56.36	7	116	1	110	8.0e-40	155	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
644377366	347	50.86	1	347	2	349	6.0e-116	410	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
644377367	130	60.77	1	130	1	130	2.0e-45	174	COG0103	Ribosomal protein S9	130
644377368	142	65.03	1	142	1	143	2.0e-54	204	COG0102	Ribosomal protein L13	148
644377369	733	49.45	13	733	4	701	0.0e+00	802	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
644377370	346	45.38	1	344	7	342	4.0e-101	361	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
644377371	844	42.44	460	833	4	380	9.0e-101	361	COG0116	23S rRNA G2445 N2-methylase RlmL	381
644377372	447	52.76	2	413	1	408	7.0e-106	377	COG1301	Na+/H+-dicarboxylate symporter	415
644377374	259	30.08	138	259	1	123	7.0e-17	81.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644377377	216	38.6	5	215	2	211	7.0e-31	127	COG0625	Glutathione S-transferase	211
644377378	327	27.09	30	327	19	266	7.0e-36	144	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
644377379	376	23.15	1	372	7	418	1.0e-82	300	COG3508	Homogentisate 1,2-dioxygenase	427
644377380	360	61.47	9	360	16	362	0.0e+00	475	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
644377381	261	47.27	29	247	39	256	2.0e-59	222	COG3186	Phenylalanine-4-hydroxylase	291
644377382	159	48.05	1	153	1	154	1.0e-37	148	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644377383	185	46.1	23	176	10	162	2.0e-39	154	COG2862	Uncharacterized membrane protein YqhA	169
644377384	278	39.01	1	278	10	289	4.0e-73	268	COG0685	5,10-methylenetetrahydrofolate reductase	291
644377385	470	53.71	8	462	2	420	0.0e+00	632	COG0499	S-adenosylhomocysteine hydrolase	420
644377386	389	69.15	1	389	2	388	0.0e+00	672	COG0192	S-adenosylmethionine synthetase	388
644377387	295	41.43	4	282	20	297	2.0e-62	233	COG1560	Lauroyl/myristoyl acyltransferase	308
644377388	288	41.58	1	288	18	307	9.0e-71	260	COG1560	Lauroyl/myristoyl acyltransferase	308
644377390	484	47.03	6	476	3	470	7.0e-98	351	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
644377391	497	53.44	5	497	5	491	0.0e+00	527	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
644377392	683	42.92	7	675	1	606	0.0e+00	500	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
644377393	101	57.43	1	101	1	100	1.0e-19	88.2	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
644377394	214	43.53	1	170	1	166	2.0e-28	118	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
644377395	162	43.98	2	162	1	161	4.0e-44	170	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
644377396	349	51.04	8	344	3	330	7.0e-97	347	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
644377397	785	37.63	1	744	1	693	0.0e+00	593	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
644377398	431	62.07	19	423	21	424	0.0e+00	638	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
644377399	166	42.17	1	166	4	157	1.0e-40	158	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
644377400	417	59.71	1	417	9	398	0.0e+00	621	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
644377401	197	44.63	4	180	5	171	1.0e-46	179	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
644377402	158	70.7	2	158	12	168	4.0e-76	276	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
644377403	118	61.02	1	118	4	121	6.0e-31	126	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
644377405	237	44.54	2	237	17	251	1.0e-59	223	COG0149	Triosephosphate isomerase	251
644377406	346	35.78	7	326	25	318	1.0e-57	217	COG0226	ABC-type phosphate transport system, periplasmic component	318
644377407	320	46.52	6	316	7	310	7.0e-77	280	COG0573	ABC-type phosphate transport system, permease component	310
644377408	308	45.45	30	308	7	292	4.0e-72	265	COG0581	ABC-type phosphate transport system, permease component	292
644377409	254	67.32	1	254	1	253	2.0e-127	448	COG1117	ABC-type phosphate transport system, ATPase component	253
644377411	682	54.42	12	673	16	675	0.0e+00	839	COG1200	RecG-like helicase	677
644377412	144	28.06	12	144	26	161	1.0e-12	66.2	COG4731	Uncharacterized conserved protein, DUF2147 family	162
644377413	281	40.41	1	278	1	291	9.0e-59	220	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
644377414	416	70.5	1	400	1	400	0.0e+00	524	COG3633	Na+/serine symporter	407
644377415	127	48.44	1	127	2	129	4.0e-32	130	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
644377416	396	47.52	19	394	34	412	3.0e-109	388	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
644377417	197	49.23	4	197	3	194	2.0e-60	225	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
644377418	313	37.97	1	289	18	301	3.0e-72	265	COG0042	tRNA-dihydrouridine synthase	323
644377419	895	37.18	12	591	4	532	1.0e-120	428	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
644377427	190	28.57	32	188	10	154	9.0e-19	86.8	COG1225	Peroxiredoxin	157
644377431	432	29.8	33	414	2	387	2.0e-50	193	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644377432	276	46.42	7	270	10	267	5.0e-57	214	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
644377433	323	47.97	26	321	2	286	2.0e-73	269	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
644377434	376	47.92	15	374	2	350	6.0e-118	417	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644377435	366	45.26	1	366	5	363	5.0e-85	308	COG0687	Spermidine/putrescine-binding periplasmic protein	363
644377436	472	43.9	25	470	4	449	0.0e+00	523	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
644377437	442	36.26	8	439	10	441	2.0e-117	416	COG0174	Glutamine synthetase	443
644377438	248	46.77	1	243	1	241	2.0e-69	255	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
644377440	182	27.73	64	182	10	114	3.0e-08	52	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
644377441	496	49.16	21	495	2	470	0.0e+00	477	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644377442	235	45.02	3	231	1	227	3.0e-54	205	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644377443	445	30.79	103	422	6	328	3.0e-37	149	COG0642	Signal transduction histidine kinase	336
644377445	267	26.34	5	260	7	247	2.0e-32	133	COG3591	V8-like Glu-specific endopeptidase	251
644377446	238	60.08	1	237	8	230	2.0e-78	285	COG0689	Ribonuclease PH	230
644377447	272	37.61	11	226	40	254	6.0e-39	154	COG0631	Serine/threonine protein phosphatase PrpC	262
644377448	322	27.38	18	316	1	305	6.0e-31	128	COG0515	Serine/threonine protein kinase	384
644377449	288	50.69	1	288	1	290	6.0e-78	284	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
644377450	423	20.39	143	381	45	281	8.0e-07	48.7	COG4974	Site-specific recombinase XerD	300
644377452	343	22.81	6	337	5	300	3.0e-12	66.2	COG4643	Uncharacterized domain associated with phage/plasmid primase	366
644377455	439	40.19	4	419	1	396	8.0e-98	351	COG1252	NADH dehydrogenase, FAD-containing subunit	405
644377456	302	29	6	299	1	297	7.0e-38	151	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377457	224	32.41	1	214	1	210	1.0e-26	113	COG0625	Glutathione S-transferase	211
644377461	527	31.77	5	527	18	553	2.0e-86	313	COG0747	ABC-type transport system, periplasmic component	556
644377462	996	33.03	238	893	1	642	3.0e-108	386	COG1020	Non-ribosomal peptide synthetase component F	642
644377463	314	26.07	56	299	2	247	7.0e-15	75.1	COG3319	Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase	257
644377464	377	37.29	18	368	1	341	7.0e-61	227	COG1566	Multidrug resistance efflux pump	352
644377466	474	33.62	12	472	1	452	5.0e-53	202	COG1538	Outer membrane protein TolC	457
644377468	413	25.06	1	383	5	380	4.0e-40	159	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
644377469	246	36.36	62	246	42	228	4.0e-25	108	COG2977	4'-phosphopantetheinyl transferase EntD (siderophore biosynthesis)	228
644377471	296	29.39	4	292	1	292	4.0e-33	135	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377472	249	39.53	1	247	1	251	5.0e-44	171	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644377473	442	18.47	26	435	21	418	8.0e-16	78.7	COG2271	Sugar phosphate permease	448
644377474	284	49.79	12	246	10	243	1.0e-88	319	COG3959	Transketolase, N-terminal subunit	243
644377475	332	45.1	28	332	10	312	1.0e-96	346	COG3958	Transketolase, C-terminal subunit	312
644377476	317	34.54	6	304	2	296	2.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377477	181	31.25	1	181	4	206	8.0e-29	119	COG0655	Multimeric flavodoxin WrbA	207
644377478	134	27.62	12	114	20	124	3.0e-13	67.7	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
644377480	290	46.71	2	288	61	339	2.0e-91	329	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
644377483	152	52.29	1	152	3	155	5.0e-56	210	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
644377484	736	31.01	54	735	36	726	2.0e-109	390	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
644377485	334	34.42	6	313	1	259	4.0e-48	185	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
644377486	204	33.51	9	197	5	194	7.0e-29	120	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
644377488	1250	71.01	1	1238	1	1227	0.0e+00	2064	COG5013	Nitrate reductase alpha subunit	1227
644377489	519	71.08	1	496	1	498	0.0e+00	872	COG1140	Nitrate reductase beta subunit	513
644377490	222	42.17	3	168	1	161	7.0e-32	130	COG2180	Nitrate reductase assembly protein NarJ, required for insertion of molybdenum cofactor	179
644377491	236	45.7	7	225	5	223	6.0e-47	180	COG2181	Nitrate reductase gamma subunit	228
644377494	161	58.39	1	161	3	162	2.0e-65	241	COG1839	Adenosine/AMP kinase	162
644377495	276	28.27	1	276	4	260	3.0e-32	132	COG0300	Short-chain dehydrogenase	265
644377496	408	30.98	30	407	40	432	8.0e-56	211	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
644377497	938	51	3	938	1	876	0.0e+00	1157	COG0525	Valyl-tRNA synthetase	877
644377503	323	36.84	3	323	3	322	4.0e-61	228	COG0598	Mg2+ and Co2+ transporter CorA	322
644377505	105	44.76	1	105	2	105	9.0e-17	78.6	COG2076	Multidrug transporter EmrE and related cation transporters	106
644377508	308	48.88	1	301	2	307	1.0e-71	263	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
644377510	302	40.75	7	297	4	291	2.0e-55	209	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
644377511	97	39.02	4	85	6	87	1.0e-13	68.3	COG4095	Uncharacterized conserved protein, contains PQ loop repeat	89
644377513	506	21.44	22	470	1	443	3.0e-17	83.7	COG1538	Outer membrane protein TolC	457
644377514	253	22.43	5	252	20	291	1.0e-09	57.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644377517	185	23.24	14	153	12	153	7.0e-07	47.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
644377519	195	35.9	1	195	1	170	7.0e-27	113	COG4675	Microcystin-dependent protein  (function unknown)	170
644377521	402	58.23	6	400	2	396	0.0e+00	566	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
644377522	244	40.56	5	244	3	239	9.0e-48	183	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
644377523	374	44.89	30	373	57	399	2.0e-79	289	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
644377526	111	30.91	5	106	10	116	5.0e-12	63.1	COG0727	Fe-S-cluster containining protein	132
644377527	118	27.84	14	110	10	96	6.0e-11	59.6	COG4309	Uncharacterized conserved protein, DUF2249 family	98
644377528	438	44.71	1	421	29	451	5.0e-118	418	COG0513	Superfamily II DNA and RNA helicase	513
644377529	290	42.36	2	288	1	286	9.0e-69	253	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
644377530	343	34.54	74	322	1	249	7.0e-57	214	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644377533	333	55.45	4	333	2	324	0.0e+00	463	COG0158	Fructose-1,6-bisphosphatase	326
644377535	173	28.27	1	169	7	197	6.0e-23	100	COG0791	Cell wall-associated hydrolase, NlpC family	197
644377536	637	43.99	1	534	1	529	0.0e+00	539	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644377539	424	43.63	4	418	2	419	1.0e-117	416	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
644377540	270	24.62	63	259	24	213	6.0e-08	51.6	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
644377541	185	29.19	1	160	1	161	2.0e-21	95.7	COG1286	Uncharacterized membrane protein, required for colicin V production	182
644377542	511	54.49	1	485	4	470	0.0e+00	609	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
644377543	394	48.45	10	393	6	392	7.0e-129	454	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
644377544	227	21.26	19	192	8	177	3.0e-10	58.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644377545	817	26.8	120	514	5	382	1.0e-42	168	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644377546	126	35.96	8	120	13	126	8.0e-24	102	COG1607	Acyl-CoA hydrolase	157
644377547	486	30.99	4	486	2	440	3.0e-77	283	COG2067	Long-chain fatty acid transport protein	440
644377548	791	34.8	8	299	3	286	1.0e-61	232	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
644377549	400	40.2	6	399	2	391	2.0e-78	286	COG0183	Acetyl-CoA acetyltransferase	392
644377551	264	54.65	5	262	1	253	9.0e-80	290	COG0134	Indole-3-glycerol phosphate synthase	254
644377552	320	42.63	6	314	23	341	2.0e-80	292	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
644377553	193	45.2	2	177	7	169	7.0e-45	173	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
644377554	181	51.59	14	169	28	184	5.0e-41	160	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
644377555	448	39.56	14	445	2	453	4.0e-92	331	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
644377557	381	19.87	3	306	8	265	5.0e-20	92.1	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
644377558	163	36.75	1	163	7	168	6.0e-19	87	COG1495	Disulfide bond formation protein DsbB	170
644377565	321	68.14	2	318	1	317	0.0e+00	513	COG0825	Acetyl-CoA carboxylase alpha subunit	317
644377566	447	35.14	31	297	26	291	9.0e-44	171	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
644377567	229	33.63	10	228	12	233	2.0e-23	102	COG0670	Integral membrane protein, interacts with FtsH	233
644377569	435	41.99	1	435	1	441	9.0e-89	321	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
644377570	207	70.41	12	207	3	198	4.0e-86	310	COG0740	ATP-dependent protease ClpP, protease subunit	200
644377571	424	71.78	14	424	1	407	0.0e+00	686	COG1219	ATP-dependent protease Clp, ATPase subunit	408
644377572	803	67.14	4	781	1	782	0.0e+00	1170	COG0466	ATP-dependent Lon protease, bacterial type	782
644377578	193	57.29	1	193	2	200	5.0e-73	267	COG0605	Superoxide dismutase	204
644377579	390	47.52	1	389	1	402	2.0e-130	458	COG2081	Predicted flavoprotein YhiN	408
644377580	471	52.61	19	459	1	434	0.0e+00	558	COG0305	Replicative DNA helicase	435
644377581	102	55.56	47	100	1	54	1.0e-15	75	COG3411	(2Fe-2S) ferredoxin	64
644377582	202	39.11	5	202	4	204	9.0e-49	186	COG2945	Alpha/beta superfamily hydrolase	210
644377583	299	41.08	1	295	4	293	4.0e-76	278	COG1131	ABC-type multidrug transport system, ATPase component	293
644377584	265	51.74	1	256	1	253	6.0e-96	343	COG0024	Methionine aminopeptidase	255
644377585	374	19.68	7	374	1	354	2.0e-29	123	COG3203	Outer membrane protein (porin)	354
644377587	708	30.7	12	707	2	636	9.0e-112	398	COG1199	Rad3-related DNA helicase	654
644377588	652	40.76	137	616	5	525	4.0e-121	428	COG1982	Arginine/lysine/ornithine decarboxylase	557
644377589	307	50.65	1	301	3	309	2.0e-112	399	COG0078	Ornithine carbamoyltransferase	310
644377590	406	54.95	1	402	1	397	0.0e+00	576	COG0137	Argininosuccinate synthase	403
644377592	487	50.11	18	486	1	462	0.0e+00	501	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
644377593	244	43.44	26	243	2	219	1.0e-38	152	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
644377594	249	31.03	5	230	8	232	1.0e-23	103	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644377595	226	61.78	1	225	1	220	9.0e-87	312	COG0036	Pentose-5-phosphate-3-epimerase	220
644377596	126	42.86	1	126	1	126	4.0e-39	153	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
644377597	597	61.21	91	584	1	495	0.0e+00	653	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
644377598	485	30.96	7	484	2	414	4.0e-75	275	COG2195	Di- or tripeptidase	414
644377599	261	48.02	15	261	20	271	1.0e-70	259	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
644377600	377	37.4	9	367	2	362	5.0e-83	301	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
644377601	397	21.91	8	390	2	385	6.0e-14	72.2	COG0475	Kef-type K+ transport system, membrane component KefB	397
644377602	257	46.56	8	253	11	255	6.0e-67	247	COG3228	Mlc titration factor MtfA, regulates ptsG expression	266
644377604	242	59.24	5	242	4	240	4.0e-94	337	COG0052	Ribosomal protein S2	252
644377605	289	55.93	1	288	1	295	1.0e-82	300	COG0264	Translation elongation factor EF-Ts	296
644377606	239	60.5	3	239	1	238	3.0e-89	321	COG0528	Uridylate kinase	238
644377607	185	54.59	1	185	3	187	3.0e-65	241	COG0233	Ribosome recycling factor	187
644377608	227	54.95	1	216	24	245	4.0e-79	287	COG0020	Undecaprenyl pyrophosphate synthase	245
644377609	268	35.91	1	257	1	255	1.0e-29	123	COG0575	CDP-diglyceride synthetase	265
644377610	392	60.21	3	383	1	373	0.0e+00	547	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
644377612	762	42.82	1	762	1	766	0.0e+00	694	COG4775	Outer membrane protein assembly factor BamA	766
644377613	164	34.32	3	164	1	169	2.0e-16	79.2	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
644377614	349	50.6	3	337	4	338	2.0e-94	339	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
644377615	150	58.33	9	150	5	146	2.0e-46	178	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
644377616	257	60	3	257	6	260	1.0e-104	372	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
644377617	391	49.74	11	387	1	379	2.0e-115	409	COG0763	Lipid A disaccharide synthetase	381
644377618	193	55.26	1	187	1	190	1.0e-61	228	COG0164	Ribonuclease HII	199
644377619	161	43.48	8	159	2	162	5.0e-30	123	COG3663	G:T/U-mismatch repair DNA glycosylase	169
644377621	169	42.94	1	159	2	161	2.0e-35	142	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
644377622	400	50.25	1	399	3	402	3.0e-105	375	COG0303	Molybdopterin biosynthesis enzyme	404
644377624	126	43.9	7	126	1	123	2.0e-22	98.2	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
644377626	285	27.82	25	271	19	282	2.0e-20	93.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644377627	310	39.87	9	160	8	164	2.0e-31	130	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
644377628	345	29.23	24	345	17	329	2.0e-45	176	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
644377629	490	46.03	5	480	1	471	0.0e+00	479	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644377631	340	30.68	5	338	3	363	1.0e-50	193	COG0687	Spermidine/putrescine-binding periplasmic protein	363
644377632	294	45.79	27	290	12	284	4.0e-55	208	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
644377633	266	40	12	266	10	264	3.0e-49	188	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
644377634	356	50.14	1	356	1	351	3.0e-114	405	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644377635	483	52.24	13	479	2	467	0.0e+00	538	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644377636	246	42.72	14	225	13	224	2.0e-29	122	COG1802	DNA-binding transcriptional regulator, GntR family	230
644377637	284	40.89	8	261	12	277	1.0e-57	216	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
644377638	281	23.08	16	254	16	255	8.0e-18	84.5	COG1082	Sugar phosphate isomerase/epimerase	274
644377639	858	56.4	5	858	1	782	0.0e+00	959	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
644377640	427	33.77	41	267	17	241	7.0e-36	145	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644377642	190	60.43	5	190	2	188	5.0e-78	283	COG2818	3-methyladenine DNA glycosylase Tag	188
644377643	194	33.16	1	187	3	189	3.0e-32	131	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
644377644	426	26.96	29	368	3	335	1.0e-49	191	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
644377645	304	33.33	51	298	8	250	5.0e-43	168	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
644377646	263	50	4	261	3	248	3.0e-89	321	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
644377647	403	36.63	1	402	3	417	1.0e-82	300	COG2223	Nitrate/nitrite transporter NarK	417
644377648	556	29.41	1	230	4	255	3.0e-37	150	COG0631	Serine/threonine protein phosphatase PrpC	262
644377649	295	29.87	5	289	1	296	1.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377651	810	59.93	1	806	1	791	0.0e+00	1134	COG1251	NAD(P)H-nitrite reductase, large subunit	793
644377652	103	44.23	1	102	3	105	4.0e-22	96.2	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
644377654	251	50.63	1	239	1	238	2.0e-68	252	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
644377655	353	26.83	1	353	1	354	3.0e-30	125	COG3203	Outer membrane protein (porin)	354
644377656	398	57.58	1	396	1	396	0.0e+00	594	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
644377657	148	28.15	2	134	1	123	1.0e-12	66.1	COG1699	Flagellar assembly factor FliW	146
644377660	447	41.96	1	396	4	346	2.0e-107	383	COG0826	Collagenase-like protease, PrtC family	347
644377661	572	42.22	1	572	1	577	0.0e+00	561	COG0018	Arginyl-tRNA synthetase	577
644377662	225	21.56	5	215	53	269	2.0e-14	72.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644377663	393	49.01	1	393	1	392	1.0e-93	337	COG0183	Acetyl-CoA acetyltransferase	392
644377664	589	45.37	124	577	1	444	0.0e+00	481	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
644377665	217	45.73	12	207	58	254	1.0e-60	226	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
644377666	136	51.04	7	102	2	97	7.0e-21	93.1	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
644377668	468	56.1	2	465	1	419	0.0e+00	617	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
644377670	212	54.25	1	212	1	191	7.0e-77	280	COG0066	3-isopropylmalate dehydratase small subunit	191
644377671	354	52.79	1	354	4	345	3.0e-124	438	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
644377672	370	31.71	1	368	2	334	2.0e-93	336	COG0136	Aspartate-semialdehyde dehydrogenase	334
644377673	337	38.55	7	330	4	333	7.0e-70	257	COG0136	Aspartate-semialdehyde dehydrogenase	334
644377674	777	29.43	5	623	22	675	4.0e-47	183	COG3170	Tfp pilus assembly protein FimV	755
644377675	730	26.06	161	674	35	623	2.0e-26	114	COG3170	Tfp pilus assembly protein FimV	755
644377677	262	51.01	1	247	2	248	9.0e-88	316	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
644377678	207	43.54	2	205	1	208	4.0e-59	221	COG0135	Phosphoribosylanthranilate isomerase	208
644377679	399	69.9	5	396	1	391	0.0e+00	693	COG0133	Tryptophan synthase beta chain	396
644377680	262	50	1	262	1	264	2.0e-82	299	COG0159	Tryptophan synthase alpha chain	265
644377681	289	58.48	1	289	1	288	4.0e-116	411	COG0777	Acetyl-CoA carboxylase beta subunit	294
644377682	409	41.87	8	336	1	324	4.0e-87	315	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
644377683	462	39.26	9	462	1	456	9.0e-90	324	COG0277	FAD/FMN-containing dehydrogenase	459
644377684	264	29	4	217	3	228	1.0e-31	130	COG0338	Site-specific DNA-adenine methylase	274
644377688	191	33.16	6	190	3	187	6.0e-31	127	COG3778	Uncharacterized protein YmfQ in lambdoid prophage, DUF2313 family	188
644377689	357	28.53	3	356	2	353	8.0e-47	181	COG3299	Uncharacterized phage protein gp47/JayE	353
644377690	116	35.83	8	116	16	135	8.0e-14	68.9	COG4381	Mu-like prophage protein gp46	135
644377692	215	41.06	3	208	4	203	6.0e-41	160	COG4384	Mu-like prophage protein gp45	203
644377693	374	42.97	1	361	1	364	1.0e-71	264	COG4379	Mu-like prophage tail protein gpP	386
644377694	409	21.98	3	409	5	451	8.0e-37	148	COG4228	Mu-like prophage DNA circulation protein	451
644377699	472	39.67	1	471	1	487	6.0e-101	361	COG4386	Mu-like prophage tail sheath protein gpL	487
644377701	221	36.57	6	136	1	133	5.0e-18	84.7	COG5003	Mu-like prophage protein gp37	151
644377702	140	47.06	1	136	1	133	3.0e-32	131	COG4387	Mu-like prophage protein gp36	139
644377704	303	53.9	1	303	1	308	3.0e-99	355	COG4397	Mu-like prophage major head subunit gpT	308
644377705	342	38.23	1	342	1	356	2.0e-57	216	COG4388	Mu-like prophage I protein	357
644377707	179	34.46	1	176	1	136	1.0e-22	99.7	COG5005	Mu-like prophage protein gpG	140
644377709	516	49.8	11	516	13	515	0.0e+00	538	COG4383	Mu-like prophage protein gp29	517
644377710	517	39.17	7	506	4	497	4.0e-126	445	COG4373	Mu-like prophage FluMu protein gp28	509
644377720	140	28.48	9	135	5	153	3.0e-10	57.7	COG4382	Mu-like prophage protein gp16	170
644377729	227	29.63	40	226	31	212	2.0e-22	99.4	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
644377730	271	33.65	54	259	2	200	9.0e-36	143	COG0625	Glutathione S-transferase	211
644377732	369	40.71	111	363	5	256	3.0e-68	252	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644377733	366	47.16	11	361	2	339	8.0e-95	340	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
644377734	272	39.53	8	257	1	252	8.0e-61	227	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
644377735	186	33.97	23	178	18	165	1.0e-31	129	COG0835	Chemotaxis signal transduction protein	165
644377736	546	33.68	162	501	29	408	7.0e-36	145	COG0840	Methyl-accepting chemotaxis protein	408
644377737	722	37.73	1	715	6	716	0.0e+00	557	COG0643	Chemotaxis protein histidine kinase CheA	716
644377742	389	50.26	11	388	9	389	2.0e-125	442	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
644377743	317	30.23	1	300	1	296	3.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377744	390	44.41	6	296	1	288	3.0e-72	265	COG0523	GTPase, G3E family	323
644377745	67	76.12	1	67	1	65	4.0e-25	106	COG2879	Uncharacterized short protein YbdD, DUF466 family	65
644377746	687	44.9	32	684	1	575	0.0e+00	586	COG1966	Carbon starvation protein CstA	575
644377747	446	47.2	1	445	1	446	1.0e-128	453	COG4564	Signal transduction histidine kinase	459
644377748	215	45.02	12	215	1	211	2.0e-50	192	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644377749	635	47.74	1	522	3	530	0.0e+00	556	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644377750	341	55.56	1	340	1	339	4.0e-123	434	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
644377751	139	44.85	1	136	2	136	1.0e-37	148	COG1765	Uncharacterized OsmC-related protein	137
644377752	136	42.22	2	135	1	133	1.0e-27	115	COG1815	Flagellar basal body rod protein FlgB	133
644377753	136	58.39	1	136	1	137	2.0e-42	164	COG1558	Flagellar basal body rod protein FlgC	137
644377754	230	33.04	1	230	1	222	3.0e-25	108	COG1843	Flagellar hook assembly protein FlgD	222
644377755	419	44.58	1	419	3	422	2.0e-79	290	COG1749	Flagellar hook protein FlgE	423
644377756	246	45.63	1	246	1	251	4.0e-62	231	COG4787	Flagellar basal body rod protein FlgF	251
644377757	260	51.52	1	260	1	263	4.0e-77	281	COG4786	Flagellar basal body rod protein FlgG	265
644377758	227	38.56	1	224	1	230	1.0e-43	170	COG2063	Flagellar basal body L-ring protein FlgH	230
644377759	366	57.1	1	366	2	365	8.0e-117	413	COG1706	Flagellar basal body P-ring protein FlgI	365
644377760	322	39.39	147	311	22	178	1.0e-34	140	COG1705	Flagellum-specific peptidoglycan hydrolase FlgJ	201
644377761	598	31.77	4	597	5	550	1.0e-83	304	COG1256	Flagellar hook-associated protein FlgK	552
644377762	304	21.57	1	303	1	357	6.0e-25	108	COG1344	Flagellin and related hook-associated protein FlgL	360
644377763	337	40.67	9	335	3	321	5.0e-75	274	COG2988	Succinylglutamate desuccinylase	324
644377764	263	31.92	1	259	2	257	7.0e-35	140	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
644377765	262	28.16	4	259	5	278	1.0e-20	94	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644377766	590	35.32	7	255	3	251	1.0e-47	184	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644377767	381	50	19	379	3	350	8.0e-119	420	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644377768	306	46.78	12	306	6	287	2.0e-70	259	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
644377769	299	45.04	11	271	13	267	2.0e-55	209	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
644377770	460	52.98	275	441	6	172	5.0e-44	172	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644377771	629	51.66	1	628	23	650	0.0e+00	816	COG1166	Arginine decarboxylase (spermidine biosynthesis)	652
644377772	433	43.07	10	417	12	411	8.0e-91	327	COG1301	Na+/H+-dicarboxylate symporter	415
644377773	620	43.65	5	614	2	603	0.0e+00	566	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
644377774	441	47.58	8	441	6	456	0.0e+00	505	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644377775	709	27.73	365	703	66	400	5.0e-43	169	COG0840	Methyl-accepting chemotaxis protein	408
644377776	321	50.48	11	319	3	300	1.0e-91	330	COG2040	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)	300
644377777	227	46.26	5	227	2	227	4.0e-56	211	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644377778	890	53.63	1	890	1	890	0.0e+00	967	COG2205	K+-sensing histidine kinase KdpD	890
644377779	191	59.47	1	189	1	190	3.0e-64	237	COG2156	K+-transporting ATPase, c chain	190
644377780	706	70.38	19	706	1	681	0.0e+00	1003	COG2216	High-affinity K+ transport system, ATPase chain B	681
644377781	498	63.03	1	495	97	560	0.0e+00	608	COG2060	K+-transporting ATPase, A chain	560
644377785	623	33.91	276	623	66	408	2.0e-54	207	COG0840	Methyl-accepting chemotaxis protein	408
644377787	708	24.12	31	255	23	249	6.0e-28	119	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
644377789	398	28.31	9	389	1	380	9.0e-23	101	COG2814	Predicted arabinose efflux permease, MFS family	394
644377791	303	35.97	4	302	3	296	1.0e-36	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377792	376	27.49	26	365	44	327	7.0e-33	135	COG3608	Predicted deacylase	331
644377793	196	30.89	6	190	10	199	3.0e-40	158	COG1573	Uracil-DNA glycosylase	202
644377794	294	27.35	44	282	37	277	8.0e-08	51.4	COG5006	Threonine/homoserine efflux transporter RhtA	292
644377797	212	36.82	12	202	14	213	3.0e-29	121	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
644377798	170	47.2	1	161	2	157	1.0e-46	179	COG0242	Peptide deformylase	168
644377799	240	22.14	1	239	3	262	6.0e-13	68.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644377800	483	46.74	7	480	1	452	4.0e-126	445	COG2079	2-methylcitrate dehydratase PrpD	453
644377801	395	66.33	5	395	2	378	0.0e+00	545	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
644377802	870	51.09	1	865	1	861	0.0e+00	1110	COG1048	Aconitase A	861
644377803	382	47.26	7	382	11	390	3.0e-120	425	COG0372	Citrate synthase	390
644377804	291	64.69	3	288	5	289	5.0e-103	367	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
644377805	199	36.7	7	194	2	182	1.0e-31	129	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644377807	319	24.22	1	315	3	315	2.0e-28	120	COG3026	Negative regulator of sigma E activity	320
644377808	155	27.54	1	136	1	138	5.0e-15	73.8	COG3086	Positive regulator of sigma E activity	150
644377809	473	43.45	6	361	9	347	3.0e-73	269	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
644377811	597	72.07	1	597	6	603	0.0e+00	1065	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
644377814	238	49.57	4	232	2	234	2.0e-64	238	COG0571	dsRNA-specific ribonuclease	235
644377815	296	51.36	5	295	3	295	7.0e-104	370	COG1159	GTPase Era, involved in 16S rRNA processing	298
644377816	116	27.78	21	106	14	103	2.0e-11	61.1	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
644377817	242	31.85	2	242	1	248	8.0e-38	150	COG1381	Recombinational DNA repair protein (RecF pathway)	251
644377818	245	65.02	2	241	1	243	1.0e-86	312	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
644377819	137	45.67	1	127	1	127	2.0e-34	137	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
644377820	361	43.9	5	344	1	335	4.0e-82	298	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
644377821	388	24.34	67	330	74	332	2.0e-24	107	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
644377823	1314	40.94	39	730	11	718	0.0e+00	608	COG1643	HrpA-like RNA helicase	845
644377824	311	26.33	1	298	1	294	5.0e-33	135	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377825	360	56.3	1	354	1	345	1.0e-115	410	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
644377826	275	72.58	20	267	9	256	5.0e-105	374	COG4208	ABC-type sulfate transport system, permease component	287
644377827	278	57.3	2	275	1	274	7.0e-77	280	COG0555	ABC-type sulfate transport system, permease component	274
644377828	334	71.39	3	334	15	346	0.0e+00	538	COG1613	ABC-type sulfate transport system, periplasmic component	348
644377829	493	30.64	194	490	115	408	2.0e-40	160	COG0840	Methyl-accepting chemotaxis protein	408
644377830	695	53.96	372	694	1	327	8.0e-112	398	COG0280	Phosphotransacetylase	327
644377831	400	55.33	5	393	3	393	0.0e+00	525	COG0282	Acetate kinase	396
644377832	369	21.41	15	369	3	362	7.0e-33	134	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
644377835	295	27.82	25	152	7	139	8.0e-08	51.4	COG2510	Uncharacterized membrane protein	140
644377837	767	60.49	1	767	6	779	0.0e+00	985	COG2183	Transcriptional accessory protein Tex/SPT6	780
644377838	222	34.45	1	209	34	242	8.0e-40	156	COG1414	DNA-binding transcriptional regulator, IclR family	246
644377839	326	21.86	17	318	1	298	2.0e-33	136	COG0714	MoxR-like ATPase	329
644377840	575	30.59	19	571	27	620	2.0e-69	256	COG4547	Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib...	620
644377841	122	40	24	118	22	116	1.0e-26	111	COG3450	Predicted enzyme of the cupin superfamily	116
644377844	625	30.05	260	625	48	408	2.0e-48	187	COG0840	Methyl-accepting chemotaxis protein	408
644377846	339	50.15	4	329	2	323	3.0e-88	318	COG0280	Phosphotransacetylase	327
644377848	603	35.08	15	583	1	537	1.0e-121	430	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
644377849	281	35.71	23	260	5	242	2.0e-47	183	COG1414	DNA-binding transcriptional regulator, IclR family	246
644377850	414	29.95	1	414	5	377	7.0e-40	158	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644377854	215	40.83	1	215	3	217	1.0e-39	156	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
644377855	509	54.09	6	343	7	347	1.0e-123	436	COG1171	Threonine dehydratase	347
644377856	380	47.11	4	379	8	386	6.0e-105	374	COG1686	D-alanyl-D-alanine carboxypeptidase	389
644377857	89	37.08	1	89	2	90	1.0e-21	94.6	COG2921	Putative lipoic acid-binding regulatory protein	90
644377858	207	55.07	3	207	11	217	3.0e-70	257	COG0321	Lipoate-protein ligase B	221
644377859	315	63.7	12	313	2	303	0.0e+00	493	COG0320	Lipoate synthase	306
644377860	224	38.38	14	196	7	188	6.0e-37	147	COG3658	Cytochrome b	192
644377861	146	32.35	10	145	13	147	2.0e-21	94.7	COG3909	Cytochrome c556	147
644377863	144	31.16	7	144	5	141	1.0e-23	102	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
644377864	307	34.17	6	303	3	320	1.0e-55	210	COG0523	GTPase, G3E family	323
644377866	247	40.8	1	244	3	252	2.0e-69	255	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
644377867	291	41.61	8	280	4	273	4.0e-38	151	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
644377868	296	37.33	4	294	16	300	6.0e-71	261	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
644377869	226	50.93	1	208	1	209	9.0e-35	140	COG2836	Sulfite exporter TauE/SafE	232
644377870	259	39.15	1	255	3	257	3.0e-41	162	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
644377873	89	44.32	1	88	1	86	1.0e-21	94.3	COG0271	Stress-induced morphogen (activity unknown)	90
644377874	100	55.1	1	98	1	92	6.0e-24	102	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
644377875	177	42.7	1	177	1	177	1.0e-43	169	COG2917	Intracellular septation protein A	180
644377876	313	40.96	3	244	5	253	8.0e-38	151	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
644377877	143	26.09	1	135	1	137	4.0e-11	60.7	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
644377878	206	41.92	1	193	4	201	2.0e-41	162	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
644377879	219	33.95	5	219	2	215	2.0e-41	162	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
644377880	217	24.6	7	207	7	255	2.0e-19	89.5	COG1192	Cellulose biosynthesis protein BcsQ	259
644377881	533	28.24	181	527	63	406	2.0e-44	174	COG0840	Methyl-accepting chemotaxis protein	408
644377882	150	36.67	1	147	14	158	1.0e-22	99	COG2030	Acyl dehydratase	159
644377883	856	45.62	20	855	24	862	0.0e+00	800	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
644377884	358	28.02	1	358	1	364	4.0e-49	189	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
644377885	366	29.75	1	351	2	364	6.0e-41	161	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
644377886	520	48.59	1	494	1	484	0.0e+00	544	COG0260	Leucyl aminopeptidase	485
644377887	140	30.5	1	137	1	141	1.0e-23	102	COG2927	DNA polymerase III, chi subunit	144
644377889	186	51.93	4	182	3	183	3.0e-51	194	COG2096	Cob(I)alamin adenosyltransferase	184
644377890	188	32.22	19	187	15	187	5.0e-22	97.6	COG1525	Endonuclease YncB, thermonuclease family	192
644377891	270	22.56	21	264	22	282	2.0e-11	63.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644377892	467	50.11	11	467	3	436	0.0e+00	510	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
644377893	150	53.02	3	150	7	155	3.0e-50	191	COG1225	Peroxiredoxin	157
644377894	206	35.71	27	203	4	183	7.0e-27	113	COG2840	DNA-nicking endonuclease, Smr domain	184
644377895	317	50.64	5	315	2	301	1.0e-89	323	COG0492	Thioredoxin reductase	305
644377899	199	25	11	194	9	190	6.0e-09	54.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644377900	346	38.46	2	337	1	331	2.0e-72	266	COG0859	ADP-heptose:LPS heptosyltransferase	334
644377901	67	48.98	12	60	16	62	6.0e-10	55.8	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
644377902	308	42.61	7	294	1	282	1.0e-70	259	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
644377903	890	44.51	9	890	49	956	0.0e+00	818	COG1391	Glutamine synthetase adenylyltransferase	963
644377904	1274	24.71	17	1263	3	1261	0.0e+00	477	COG3164	Uncharacterized conserved protein YhdP, contains DUF3971 and AsmA2 domains	1271
644377905	269	37.13	3	267	1	263	2.0e-57	215	COG0388	Predicted amidohydrolase	274
644377906	480	41.16	19	477	1	454	3.0e-117	415	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
644377907	305	32.33	3	296	1	293	2.0e-33	136	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377908	369	29.18	1	369	2	369	2.0e-61	229	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644377909	96	45.56	1	90	1	90	6.0e-29	118	COG4829	Muconolactone delta-isomerase	98
644377910	306	27.13	52	291	2	219	2.0e-29	123	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
644377911	455	24.64	29	441	4	352	7.0e-52	198	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
644377912	163	49.08	1	163	2	164	5.0e-47	180	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
644377913	339	31.49	108	338	6	235	1.0e-37	150	COG1018	Ferredoxin-NADP reductase	266
644377914	259	37.16	4	256	2	249	1.0e-36	147	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644377915	412	46.44	26	404	19	397	1.0e-87	316	COG3135	Predicted benzoate:H+ symporter BenE	402
644377916	312	33.57	1	272	1	271	2.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377918	460	21.71	19	436	21	430	1.0e-17	84.9	COG2271	Sugar phosphate permease	448
644377919	248	28.16	41	245	8	205	7.0e-24	104	COG0400	Predicted esterase	207
644377920	199	38.81	1	198	3	203	1.0e-35	143	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
644377921	250	40.74	12	250	3	241	5.0e-42	164	COG2186	DNA-binding transcriptional regulator, FadR family	241
644377922	303	36.54	7	301	1	295	8.0e-56	210	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
644377923	447	23.2	7	437	17	433	8.0e-29	121	COG2271	Sugar phosphate permease	448
644377924	515	44.36	108	515	1	381	6.0e-121	428	COG2721	Altronate dehydratase	381
644377925	444	26.63	7	413	1	371	1.0e-57	218	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644377926	445	29.9	10	413	4	370	1.0e-56	214	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644377927	469	26.95	2	467	29	472	3.0e-46	179	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644377929	320	25.25	11	298	1	292	3.0e-28	119	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377930	567	34.71	30	551	1	528	9.0e-124	437	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
644377931	502	40.42	10	485	1	469	2.0e-116	413	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644377932	386	49.23	1	381	1	391	2.0e-93	335	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644377934	298	48.8	3	292	2	285	6.0e-74	271	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
644377953	138	48	3	127	10	133	1.0e-29	122	COG4101	Uncharacterized protein, RmlC-like cupin domain	142
644377955	394	44.97	1	394	159	556	2.0e-100	359	COG0497	DNA repair ATPase RecN	557
644377957	291	44.41	6	288	1	281	2.0e-64	239	COG0061	NAD kinase	281
644377958	217	40.5	6	205	1	200	5.0e-55	207	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
644377959	324	26.98	112	322	3	212	6.0e-25	108	COG0569	Trk K+ transport system, NAD-binding component	225
644377960	181	56.21	1	168	6	174	2.0e-64	238	COG0225	Peptide methionine sulfoxide reductase MsrA	174
644377961	312	29.79	1	312	5	329	1.0e-57	216	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
644377964	314	55.41	1	314	1	311	1.0e-106	379	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
644377965	310	39.17	1	310	11	315	2.0e-71	262	COG0042	tRNA-dihydrouridine synthase	323
644377968	460	46.9	1	364	26	396	2.0e-111	396	COG0513	Superfamily II DNA and RNA helicase	513
644377970	209	17.79	4	202	55	262	8.0e-10	57.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644377972	637	42.92	192	636	14	445	3.0e-117	416	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
644377974	195	39.26	13	175	2	164	1.0e-35	142	COG4420	Uncharacterized membrane protein	191
644377975	103	42.86	12	102	3	93	2.0e-25	107	COG3123	Uncharacterized conserved protein YaiE, UPF0345 family	94
644377976	435	52.93	7	432	8	422	5.0e-101	361	COG0738	Fucose permease	422
644377977	257	31.95	13	250	11	250	1.0e-13	70.4	COG0730	Uncharacterized membrane protein YfcA	258
644377978	301	31.03	3	289	2	287	3.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
644377980	208	30.24	7	208	10	214	2.0e-29	122	COG2345	Predicted transcriptional regulator, ArsR family	218
644377982	301	23.3	19	296	29	292	3.0e-06	46.4	COG5006	Threonine/homoserine efflux transporter RhtA	292
644377983	290	29.17	167	286	1	120	4.0e-19	88.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644377984	212	26.73	5	180	4	205	3.0e-25	108	COG1335	Nicotinamidase-related amidase	205
644377985	287	25.54	8	266	11	283	2.0e-28	120	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
644377986	239	27.12	7	236	9	230	1.0e-25	110	COG1018	Ferredoxin-NADP reductase	266
644377988	137	36.29	8	129	17	140	7.0e-18	83.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
644377990	227	32.86	8	210	1	207	4.0e-24	105	COG0778	Nitroreductase	207
644377991	434	43.43	11	434	1	449	1.0e-127	450	COG1797	Cobyrinic acid a,c-diamide synthase	451
644377992	200	51.76	3	200	1	198	1.0e-69	255	COG2109	ATP:corrinoid adenosyltransferase	198
644377993	369	33.33	6	366	1	323	2.0e-58	219	COG0523	GTPase, G3E family	323
644377994	514	46.75	1	243	1	245	3.0e-84	305	COG1010	Precorrin-3B methylase	249
644377995	252	28.69	4	247	3	242	6.0e-27	114	COG2073	Cobalamin biosynthesis protein CbiG	298
644377996	268	58.96	1	250	3	252	2.0e-94	339	COG2875	Precorrin-4 methylase	254
644377997	243	34.87	4	240	1	234	2.0e-50	192	COG2243	Precorrin-2 methylase	234
644377998	384	43.55	8	375	1	361	6.0e-95	341	COG1903	Cobalamin biosynthesis protein CbiD	367
644377999	525	43.84	310	512	8	208	1.0e-57	217	COG2082	Precorrin isomerase	210
644378000	233	34.22	1	224	1	210	6.0e-51	194	COG2241	Precorrin-6B methylase 1	210
644378001	653	48.28	1	401	10	414	3.0e-110	393	COG1239	Mg-chelatase subunit ChlI	423
644378001	653	48.45	395	651	8	259	5.0e-59	222	COG1240	Mg-chelatase subunit ChlD	261
644378003	109	50.85	40	98	1	59	1.0e-17	81.5	COG3411	(2Fe-2S) ferredoxin	64
644378004	350	54.01	14	337	19	339	5.0e-108	384	COG3376	High-affinity nickel permease	342
644378005	420	22.62	44	410	34	384	6.0e-10	59.1	COG2814	Predicted arabinose efflux permease, MFS family	394
644378006	342	31.05	1	325	5	351	1.0e-49	190	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
644378007	312	46.37	1	306	3	315	3.0e-75	275	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
644378008	489	52.77	3	487	1	486	0.0e+00	622	COG1492	Cobyric acid synthase	486
644378011	243	28.28	3	238	5	241	7.0e-25	107	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
644378012	552	38.97	8	547	2	537	0.0e+00	502	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
644378013	227	46.26	3	216	1	210	8.0e-61	227	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
644378014	235	34.67	1	197	1	197	3.0e-37	148	COG0518	GMP synthase - Glutamine amidotransferase domain	198
644378016	197	26.92	22	196	5	185	1.0e-28	119	COG2930	Lipid-binding SYLF domain	227
644378017	210	54.4	1	192	1	185	8.0e-61	226	COG1704	Uncharacterized conserved protein	185
644378018	287	44.6	10	287	10	271	4.0e-51	195	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
644378020	462	41.11	14	462	2	436	4.0e-92	332	COG0733	Na+-dependent transporter, SNF family	439
644378021	348	29.11	7	239	5	232	4.0e-22	99.1	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
644378022	183	23.59	8	182	27	215	1.0e-06	46.5	COG3786	L,D-peptidoglycan transpeptidase YkuD, ErfK/YbiS/YcfS/YnhG family	217
644378024	555	21.7	7	456	29	416	2.0e-14	74.3	COG3540	Phosphodiesterase/alkaline phosphatase D	522
644378025	614	31.37	294	613	89	407	1.0e-45	177	COG0840	Methyl-accepting chemotaxis protein	408
644378026	573	43.73	1	324	1	326	2.0e-79	290	COG1796	DNA polymerase/3'-5' exonuclease PolX	326
644378027	181	29.03	5	97	3	90	6.0e-07	47.5	COG1544	Ribosome-associated translation inhibitor RaiA	110
644378030	385	33.33	6	376	4	379	4.0e-62	232	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
644378031	259	18.32	1	253	1	262	1.0e-05	43.9	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644378033	183	37.99	5	176	4	180	6.0e-25	107	COG3038	Cytochrome b561	181
644378035	406	28.29	1	404	1	390	5.0e-51	195	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
644378036	1140	20.53	1	789	1	747	3.0e-37	151	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
644378037	354	39.33	46	334	47	345	5.0e-76	278	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
644378041	317	28.14	53	244	52	226	3.0e-20	92.7	COG2357	ppGpp synthetase catalytic domain (RelA/SpoT-type nucleotidyltranferase)	231
644378042	360	39.17	23	358	8	339	2.0e-98	352	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
644378044	949	36.69	175	905	1	647	0.0e+00	596	COG0209	Ribonucleotide reductase alpha subunit	696
644378045	247	53.44	7	246	2	248	2.0e-79	288	COG1496	Copper oxidase (laccase) domain	249
644378046	362	48.99	23	317	2	289	2.0e-84	306	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644378047	256	41.11	1	253	11	253	9.0e-64	237	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
644378049	422	31.63	15	421	13	436	9.0e-55	207	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
644378051	112	76.79	1	112	1	112	7.0e-40	155	COG0347	Nitrogen regulatory protein PII	112
644378052	1318	36.12	162	1015	1	743	0.0e+00	723	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
644378053	303	23.1	2	296	1	297	7.0e-18	84.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378055	208	42.71	5	202	3	201	5.0e-40	157	COG1279	Arginine exporter protein ArgO	202
644378056	300	41.37	10	286	1	266	6.0e-56	211	COG2890	Methylase of polypeptide chain release factors	280
644378057	458	35.87	8	454	9	463	1.0e-101	363	COG1109	Phosphomannomutase	464
644378058	342	56.34	1	339	1	338	9.0e-118	416	COG0547	Anthranilate phosphoribosyltransferase	338
644378059	189	65.24	1	186	3	189	8.0e-84	302	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
644378061	315	38.04	11	167	5	166	5.0e-32	132	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
644378062	389	19.55	11	386	20	393	2.0e-21	97.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644378064	412	19.75	18	412	1	354	8.0e-22	98.5	COG3203	Outer membrane protein (porin)	354
644378065	445	19.95	35	436	29	433	2.0e-16	80.6	COG2271	Sugar phosphate permease	448
644378066	267	72.16	1	255	1	255	5.0e-104	370	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
644378067	267	61.05	1	267	1	262	2.0e-103	368	COG3971	2-keto-4-pentenoate hydratase	264
644378068	486	49.36	11	480	1	466	0.0e+00	523	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644378069	404	26.03	1	364	1	357	1.0e-17	84.5	COG2814	Predicted arabinose efflux permease, MFS family	394
644378070	126	65.87	1	126	1	126	7.0e-50	188	COG3232	5-carboxymethyl-2-hydroxymuconate isomerase	127
644378071	282	34.41	5	282	1	268	2.0e-76	279	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
644378072	486	48.34	2	479	1	472	0.0e+00	536	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644378073	254	46.26	23	246	39	265	9.0e-73	266	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
644378074	258	41.78	32	250	47	265	6.0e-53	200	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
644378077	426	19.12	45	413	22	419	2.0e-08	54.1	COG2211	Na+/melibiose symporter or related transporter	467
644378078	147	36.23	5	142	2	139	3.0e-21	94.6	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
644378079	300	28.46	178	300	1	123	6.0e-17	81.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644378081	326	41.38	265	322	5	62	9.0e-12	64.6	COG2771	DNA-binding transcriptional regulator, CsgD family	65
644378082	293	22.37	9	293	17	304	4.0e-07	48.8	COG4313	Uncharacterized conserved protein	304
644378084	370	42.77	29	358	11	338	8.0e-78	284	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
644378086	499	48.13	20	499	1	469	0.0e+00	491	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644378088	501	24.54	14	445	12	436	3.0e-31	129	COG0531	Amino acid transporter	466
644378090	432	24.08	26	395	2	373	2.0e-52	200	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644378091	120	28.33	1	120	1	116	6.0e-14	69.6	COG3450	Predicted enzyme of the cupin superfamily	116
644378092	160	29.03	19	141	3	126	7.0e-12	63.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
644378093	262	37.07	1	248	1	249	2.0e-37	149	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644378095	267	44.31	13	259	1	251	5.0e-44	171	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644378100	128	28.7	13	121	1	115	2.0e-09	54.9	COG2963	Transposase and inactivated derivatives	116
644378104	395	23.28	85	383	1	303	6.0e-08	52.3	COG0582	Integrase	309
644378106	541	40.49	2	537	4	533	3.0e-111	396	COG1283	Na+/phosphate symporter	533
644378107	222	28.57	1	210	5	200	1.0e-37	150	COG0560	Phosphoserine phosphatase	212
644378108	338	46.18	1	335	3	348	2.0e-103	368	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644378109	256	32	8	256	14	260	1.0e-37	149	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
644378110	296	40.57	23	296	3	282	2.0e-67	249	COG4132	ABC-type uncharacterized transport system, permease component	282
644378111	349	27.21	58	344	6	296	4.0e-35	142	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
644378112	250	36.36	8	238	6	236	2.0e-45	175	COG2188	DNA-binding transcriptional regulator, GntR family	236
644378117	114	41.74	1	114	1	115	9.0e-32	128	COG3450	Predicted enzyme of the cupin superfamily	116
644378120	334	22.42	1	327	8	316	4.0e-26	112	COG0530	Ca2+/Na+ antiporter	320
644378121	90	46.07	1	89	1	89	1.0e-19	87.6	COG1937	DNA-binding transcriptional regulator, FrmR family	89
644378128	261	31.84	21	247	11	251	3.0e-22	99	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
644378129	175	39.29	1	161	15	182	1.0e-24	105	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644378130	119	50.43	5	119	24	138	4.0e-31	126	COG4315	Predicted lipoprotein with conserved Yx(FWY)xxD motif (function unknown)	138
644378132	461	43.09	271	451	1	178	2.0e-40	160	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644378133	286	34.31	15	284	1	269	1.0e-54	207	COG0829	Urease accessory protein UreH	269
644378134	100	83.84	1	99	1	99	2.0e-44	170	COG0831	Urease gamma subunit	100
644378135	101	69.31	1	101	1	101	5.0e-43	165	COG0832	Urease beta subunit	106
644378136	566	78.66	1	566	2	568	0.0e+00	1064	COG0804	Urease alpha subunit	568
644378137	165	49.62	16	148	22	154	2.0e-31	128	COG2371	Urease accessory protein UreE	155
644378138	227	40.89	5	227	5	229	3.0e-45	175	COG0830	Urease accessory protein UreF	229
644378139	211	53.96	1	201	9	202	4.0e-66	244	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
644378140	194	43.59	1	194	9	201	1.0e-20	93.1	COG2370	Hydrogenase/urease accessory protein HupE	201
644378142	434	18.58	58	368	48	331	4.0e-07	49.7	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
644378143	172	33.83	10	142	5	132	2.0e-20	92.4	COG3791	Uncharacterized conserved protein	133
644378145	451	23.28	18	425	9	379	4.0e-17	82.9	COG2814	Predicted arabinose efflux permease, MFS family	394
644378146	234	40.95	5	234	40	263	1.0e-61	229	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
644378147	218	35.94	2	214	1	211	1.0e-31	129	COG0625	Glutathione S-transferase	211
644378148	397	29.29	3	387	1	387	5.0e-48	185	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
644378149	347	38.14	13	341	15	343	8.0e-71	261	COG3435	Gentisate 1,2-dioxygenase	351
644378150	303	24.58	5	300	2	296	5.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378151	300	30.17	3	292	2	292	1.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378152	235	55.71	6	214	4	211	3.0e-63	235	COG3531	Predicted protein-disulfide isomerase , contains CxxC motif	212
644378153	203	57.35	1	203	1	211	2.0e-70	258	COG2910	Putative NADH-flavin reductase	211
644378154	601	35.68	33	468	1	439	6.0e-61	229	COG0038	H+/Cl- antiporter ClcA	443
644378156	164	36.36	1	109	1	109	5.0e-19	87.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
644378157	769	43.2	75	768	2	709	0.0e+00	685	COG2217	Cation transport ATPase	713
644378158	161	44.37	9	159	5	154	1.0e-33	136	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644378159	343	37.27	27	340	23	310	1.0e-63	237	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
644378161	557	24.35	2	383	29	408	4.0e-36	146	COG0840	Methyl-accepting chemotaxis protein	408
644378163	344	30.29	1	344	27	402	3.0e-74	272	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
644378164	266	40.86	1	256	7	262	5.0e-69	254	COG0796	Glutamate racemase	269
644378165	554	36.56	9	426	13	436	2.0e-57	217	COG0038	H+/Cl- antiporter ClcA	443
644378166	316	38.74	1	302	1	302	2.0e-72	266	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
644378167	515	33.47	8	453	2	468	8.0e-63	235	COG3119	Arylsulfatase A or related enzyme	475
644378168	314	31.89	10	305	3	297	9.0e-36	144	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378170	281	44.53	10	274	5	266	3.0e-73	268	COG1526	Formate dehydrogenase assembly factor FdhD	266
644378171	950	46.32	17	941	2	964	0.0e+00	1232	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
644378172	514	53.11	93	509	1	418	0.0e+00	554	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
644378173	159	34.67	10	159	11	160	1.0e-34	138	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
644378174	368	39.15	135	346	4	208	5.0e-44	171	COG1910	Periplasmic molybdate-binding protein/domain	223
644378175	240	26.05	1	215	2	239	5.0e-32	131	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
644378176	584	34.1	10	293	4	300	3.0e-48	186	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
644378178	159	35.71	1	134	3	136	5.0e-28	116	COG0394	Protein-tyrosine-phosphatase	139
644378179	123	29.9	1	97	10	104	1.0e-10	58.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
644378180	417	24.42	5	416	7	417	5.0e-61	228	COG0443	Molecular chaperone DnaK (HSP70)	579
644378181	256	32.71	1	256	4	269	8.0e-39	154	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644378182	229	52.61	1	227	1	230	3.0e-72	264	COG4215	ABC-type arginine transport system, permease component	230
644378183	237	56.58	7	234	1	228	2.0e-76	278	COG4160	ABC-type arginine/histidine transport system, permease component	228
644378184	255	76.1	1	251	4	253	5.0e-117	413	COG4598	ABC-type histidine transport system, ATPase component	256
644378185	323	44.84	4	312	10	319	5.0e-76	277	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
644378186	413	50.25	1	405	4	404	0.0e+00	518	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
644378187	347	39.12	1	340	1	336	4.0e-80	291	COG3138	Arginine/ornithine N-succinyltransferase beta subunit	336
644378188	346	50.89	1	338	1	336	7.0e-107	380	COG3138	Arginine/ornithine N-succinyltransferase beta subunit	336
644378189	487	41.3	3	459	2	455	7.0e-103	368	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644378191	184	32.54	59	183	17	140	5.0e-18	84.3	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
644378193	261	38.7	1	260	1	261	2.0e-60	225	COG0300	Short-chain dehydrogenase	265
644378194	496	33.48	16	484	3	454	8.0e-50	191	COG1538	Outer membrane protein TolC	457
644378195	205	24.87	10	201	4	194	1.0e-10	59.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644378196	373	28.61	1	357	4	368	3.0e-18	86.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644378197	1033	29.04	5	1013	1	1009	0.0e+00	807	COG0841	Multidrug efflux pump subunit AcrB	1009
644378198	318	32.57	6	303	1	295	4.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378202	329	29.48	59	324	1	248	2.0e-41	163	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
644378203	295	31.67	1	295	15	297	1.0e-37	150	COG0501	Zn-dependent protease with chaperone function	302
644378204	300	25.43	5	292	1	285	4.0e-23	101	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378206	626	30.61	387	626	3	239	1.0e-25	111	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
644378207	109	40.23	21	107	14	100	4.0e-10	56.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
644378208	248	41.13	19	244	3	228	2.0e-49	189	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644378209	720	23.21	301	588	60	335	2.0e-27	117	COG0642	Signal transduction histidine kinase	336
644378210	546	35.08	20	538	10	524	1.0e-115	410	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644378211	249	47.31	1	249	1	260	4.0e-66	244	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
644378212	310	51.74	1	310	1	312	6.0e-86	310	COG2025	Electron transfer flavoprotein, alpha subunit	313
644378213	594	33.64	36	458	7	393	2.0e-64	240	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644378214	423	32.39	6	422	1	379	1.0e-74	273	COG0644	Dehydrogenase (flavoprotein)	396
644378216	1205	59.38	440	1204	1	769	0.0e+00	983	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
644378217	407	37.71	33	383	1	355	1.0e-55	210	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
644378218	342	44.94	5	332	3	337	9.0e-90	323	COG1816	Adenosine deaminase	345
644378219	200	27.69	17	184	3	196	1.0e-20	93.4	COG1335	Nicotinamidase-related amidase	205
644378220	123	35.09	6	62	5	60	4.0e-09	53.8	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
644378221	211	44.02	1	208	2	207	1.0e-53	202	COG5588	Uncharacterized protein	207
644378222	273	48.46	46	270	52	278	8.0e-45	174	COG5486	Predicted metal-binding membrane protein	283
644378223	848	35.7	16	832	44	901	0.0e+00	591	COG0474	Magnesium-transporting ATPase (P-type)	917
644378224	659	29.23	267	656	23	408	2.0e-44	174	COG0840	Methyl-accepting chemotaxis protein	408
644378225	262	63.95	1	258	1	256	2.0e-106	378	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
644378226	599	28.71	1	598	3	561	5.0e-79	289	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
644378227	351	59.28	1	347	1	361	0.0e+00	494	COG4174	ABC-type microcin C transport system, permease component YejB	364
644378228	339	58.68	5	338	7	339	7.0e-121	426	COG4239	ABC-type microcin C transport system, permease component YejE	341
644378229	522	58.22	2	520	4	532	0.0e+00	682	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
644378231	418	73.21	1	418	4	420	0.0e+00	712	COG1158	Transcription termination factor Rho	422
644378232	213	34.34	15	212	12	208	8.0e-31	127	COG2860	Uncharacterized membrane protein YeiH	209
644378235	280	51.99	6	279	2	278	7.0e-87	313	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
644378236	225	33.33	53	217	51	215	2.0e-24	106	COG3235	Uncharacterized membrane protein	223
644378237	255	20.74	35	251	45	254	4.0e-08	52.1	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
644378238	324	36.73	2	324	18	286	2.0e-66	245	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
644378239	468	34.64	10	468	9	455	3.0e-70	259	COG0534	Na+-driven multidrug efflux pump	455
644378242	455	38.31	33	425	1	399	2.0e-78	286	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
644378243	160	53.46	1	159	1	159	4.0e-48	183	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
644378244	211	33.02	1	203	1	212	3.0e-36	145	COG1428	Deoxyadenosine/deoxycytidine kinase	216
644378245	263	59.32	2	263	1	263	7.0e-102	363	COG0413	Ketopantoate hydroxymethyltransferase	268
644378246	277	59.93	1	275	1	282	1.0e-103	369	COG0414	Panthothenate synthetase	285
644378247	126	54.4	2	126	1	125	2.0e-47	181	COG0853	Aspartate 1-decarboxylase	126
644378248	136	34.35	1	131	1	129	2.0e-23	101	COG3791	Uncharacterized conserved protein	133
644378249	159	41.51	5	158	13	171	2.0e-39	155	COG0684	Regulator of RNase E activity RraA	210
644378250	508	45.11	60	404	26	346	2.0e-73	269	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
644378251	210	61.72	1	209	1	209	1.0e-84	305	COG0177	Endonuclease III	211
644378252	232	56.1	5	167	35	198	2.0e-46	179	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
644378253	694	28.23	7	694	30	750	6.0e-62	232	COG4774	Outer membrane receptor for monomeric catechols	750
644378254	362	26.03	7	360	11	398	3.0e-32	132	COG3182	Uncharacterized iron-regulated membrane protein	442
644378255	306	41.5	1	304	14	318	2.0e-86	312	COG4874	Uncharacterized protein	318
644378256	140	39.44	1	139	6	147	1.0e-23	102	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644378257	655	47.54	74	640	1	528	0.0e+00	678	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
644378258	559	55.45	32	550	1	528	0.0e+00	518	COG4147	Na+(or H+)/acetate symporter ActP	529
644378259	103	53.4	1	103	1	102	3.0e-26	109	COG3162	Uncharacterized membrane protein, DUF485 family	102
644378260	298	29.45	1	288	1	289	2.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378262	488	47.65	1	488	2	488	0.0e+00	592	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
644378263	385	30.74	114	379	5	283	4.0e-33	135	COG1408	Predicted phosphohydrolase, MPP superfamily	284
644378264	235	25.3	46	211	27	175	2.0e-22	99.2	COG2818	3-methyladenine DNA glycosylase Tag	188
644378265	379	35.75	171	376	75	281	3.0e-22	99.6	COG0842	ABC-type multidrug transport system, permease component	286
644378266	309	37.79	1	299	1	292	2.0e-71	262	COG1131	ABC-type multidrug transport system, ATPase component	293
644378267	324	28.53	11	319	25	336	2.0e-23	103	COG1566	Multidrug resistance efflux pump	352
644378268	310	35.62	1	285	2	292	1.0e-51	197	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
644378273	283	30.71	10	250	54	291	2.0e-44	172	COG0777	Acetyl-CoA carboxylase beta subunit	294
644378275	297	36.46	22	286	7	283	2.0e-40	159	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
644378277	301	28.52	7	301	1	293	4.0e-24	105	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378278	556	43.17	11	550	1	522	1.0e-122	433	COG1620	L-lactate permease	522
644378279	243	40.34	5	234	2	229	1.0e-44	173	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
644378280	163	50.3	1	163	1	157	6.0e-48	183	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
644378281	185	44.24	23	185	2	158	6.0e-47	180	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
644378282	416	29.3	1	410	4	424	2.0e-41	163	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
644378283	346	48.16	3	301	2	292	2.0e-75	276	COG1230	Co/Zn/Cd efflux system component	296
644378284	104	36.19	1	104	1	105	1.0e-07	48.3	COG0640	DNA-binding transcriptional regulator, ArsR family	110
644378285	555	42.07	14	548	13	551	5.0e-103	368	COG0659	Sulfate permease or related transporter, MFS superfamily	554
644378288	464	40	415	464	3	52	2.0e-13	70.7	COG1773	Rubredoxin	55
644378288	464	42.56	5	394	7	388	1.0e-121	430	COG0426	Flavorubredoxin	388
644378289	150	40.91	1	131	1	131	1.0e-25	109	COG1959	DNA-binding transcriptional regulator, IscR family	150
644378290	304	41.75	1	294	1	290	3.0e-37	149	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378291	421	26.58	38	415	16	390	1.0e-25	111	COG2814	Predicted arabinose efflux permease, MFS family	394
644378292	307	36.73	22	307	32	324	5.0e-59	221	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
644378293	418	35.77	10	413	4	408	5.0e-112	398	COG2081	Predicted flavoprotein YhiN	408
644378294	361	41.74	20	360	6	347	4.0e-91	328	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
644378295	206	33.67	2	196	1	197	2.0e-35	142	COG0625	Glutathione S-transferase	211
644378296	212	41.09	7	207	6	206	9.0e-30	123	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644378297	194	32.64	3	192	1	186	1.0e-33	136	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
644378299	561	31.19	22	537	1	472	8.0e-99	354	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
644378300	129	32.2	12	129	11	107	2.0e-07	47.8	COG4654	Cytochrome c551/c552	110
644378301	548	21.43	11	532	2	513	2.0e-23	104	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
644378302	71	58.9	1	71	1	73	1.0e-21	94.9	COG0254	Ribosomal protein L31	75
644378303	457	60.22	1	456	1	463	0.0e+00	683	COG0215	Cysteinyl-tRNA synthetase	464
644378305	269	27.85	1	269	7	304	5.0e-22	98.5	COG0672	High-affinity Fe2+/Pb2+ permease	383
644378307	653	37.36	82	627	1	522	0.0e+00	466	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
644378309	167	31.74	1	167	1	157	4.0e-24	104	COG3708	Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain	157
644378310	694	55.35	40	693	1	645	0.0e+00	811	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
644378311	263	37.07	1	257	2	255	8.0e-39	154	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
644378312	532	46.15	12	532	1	526	0.0e+00	643	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
644378313	389	43.88	7	389	3	391	6.0e-92	331	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644378314	135	33.06	7	125	1	119	2.0e-12	64.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
644378315	562	36.2	19	559	12	534	0.0e+00	466	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644378316	222	28.25	6	221	4	216	1.0e-24	107	COG3318	Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C motif	216
644378317	594	32.3	42	455	12	389	1.0e-74	274	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644378318	185	22.65	1	179	2	173	7.0e-17	80.7	COG3216	Uncharacterized conserved protein, DUF2062 family	184
644378321	642	67.44	4	642	2	649	0.0e+00	868	COG2766	Predicted Ser/Thr protein kinase	649
644378322	423	54.12	1	423	1	423	0.0e+00	483	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
644378323	507	66.94	1	490	1	482	0.0e+00	679	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
644378324	266	57.14	1	265	2	266	3.0e-96	344	COG0289	Dihydrodipicolinate reductase	266
644378325	128	38.89	6	126	14	135	2.0e-22	98.2	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
644378326	142	48.48	6	137	10	140	2.0e-35	141	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
644378327	233	56.81	9	221	1	213	3.0e-81	294	COG2360	Leu/Phe-tRNA-protein transferase	221
644378328	240	45.23	5	239	3	243	1.0e-72	266	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
644378329	163	34.87	15	162	4	154	5.0e-22	97.3	COG3133	Outer membrane lipoprotein SlyB	154
644378330	346	45.54	44	339	1	291	4.0e-88	318	COG0167	Dihydroorotate dehydrogenase	310
644378331	196	19	7	192	2	201	2.0e-18	85.4	COG0778	Nitroreductase	207
644378332	271	36.69	1	244	1	240	3.0e-47	182	COG1360	Flagellar motor protein MotB	244
644378333	312	28.34	7	303	2	305	2.0e-51	196	COG0616	Periplasmic serine protease, ClpP class	317
644378334	129	34.29	9	113	8	102	9.0e-12	62.7	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
644378335	219	34.1	3	215	2	218	6.0e-40	157	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
644378336	310	40.34	12	297	4	289	1.0e-73	270	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644378337	1002	53.16	1	489	1	487	0.0e+00	512	COG1530	Ribonuclease G or E	487
644378339	276	36	6	276	5	278	1.0e-23	103	COG1344	Flagellin and related hook-associated protein FlgL	360
644378341	696	46.92	1	696	6	694	0.0e+00	721	COG1298	Flagellar biosynthesis pathway, component FlhA	696
644378342	380	37.99	1	357	1	358	3.0e-88	319	COG1377	Flagellar biosynthesis protein FlhB	363
644378343	259	36.96	1	256	1	256	1.0e-33	136	COG1684	Flagellar biosynthesis protein FliR	258
644378344	90	35.96	2	90	1	89	5.0e-15	72.9	COG1987	Flagellar biosynthesis protein FliQ	89
644378345	252	46.15	5	250	2	248	8.0e-60	223	COG1338	Flagellar biosynthetic protein FliP	248
644378348	113	29.87	37	113	29	105	2.0e-06	44.5	COG1677	Flagellar hook-basal body complex protein FliE	105
644378349	543	28.52	7	539	22	545	2.0e-79	289	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
644378350	349	33.94	22	348	10	339	4.0e-54	205	COG1536	Flagellar motor switch protein FliG	339
644378351	240	25.41	48	224	58	233	2.0e-17	83.1	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
644378352	436	54.23	1	436	6	441	0.0e+00	536	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
644378354	444	28.94	6	444	16	479	3.0e-39	156	COG1345	Flagellar capping protein FliD	483
644378355	130	40	4	123	5	120	1.0e-26	112	COG1516	Flagellin-specific chaperone FliS	132
644378359	230	37.5	24	230	34	247	1.0e-37	150	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
644378360	287	30.28	1	283	3	263	1.0e-51	197	COG1291	Flagellar motor component MotA	266
644378361	325	26.39	19	284	5	242	7.0e-33	134	COG1360	Flagellar motor protein MotB	244
644378362	227	26.29	9	221	1	212	9.0e-21	93.8	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
644378365	240	37.72	70	236	25	182	5.0e-33	134	COG1705	Flagellum-specific peptidoglycan hydrolase FlgJ	201
644378366	240	31.76	69	237	50	216	7.0e-22	97.7	COG1261	Flagella basal body P-ring formation protein FlgA	220
644378367	118	37.59	2	118	1	132	9.0e-22	95.8	COG1815	Flagellar basal body rod protein FlgB	133
644378368	140	45.32	1	139	1	137	7.0e-37	146	COG1558	Flagellar basal body rod protein FlgC	137
644378369	226	28.23	11	214	10	218	6.0e-15	74.7	COG1843	Flagellar hook assembly protein FlgD	222
644378370	399	39.71	1	397	3	420	1.0e-69	257	COG1749	Flagellar hook protein FlgE	423
644378371	241	47.79	1	240	1	249	2.0e-61	229	COG4787	Flagellar basal body rod protein FlgF	251
644378372	262	48.87	1	262	1	265	7.0e-74	270	COG4786	Flagellar basal body rod protein FlgG	265
644378373	215	35.24	1	208	1	227	6.0e-45	173	COG2063	Flagellar basal body L-ring protein FlgH	230
644378374	368	52.49	9	368	7	365	3.0e-110	391	COG1706	Flagellar basal body P-ring protein FlgI	365
644378377	303	23.81	1	303	1	357	6.0e-24	104	COG1344	Flagellin and related hook-associated protein FlgL	360
644378380	529	23.11	5	239	1	222	1.0e-14	74.8	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
644378382	342	29.81	1	317	5	300	4.0e-42	165	COG4974	Site-specific recombinase XerD	300
644378387	182	26.74	15	177	4	186	6.0e-08	50.8	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
644378402	65	40	4	63	6	65	1.0e-06	45.2	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
644378410	195	32.09	6	192	3	186	1.0e-29	123	COG3778	Uncharacterized protein YmfQ in lambdoid prophage, DUF2313 family	188
644378411	365	26.67	5	365	4	351	6.0e-27	115	COG3299	Uncharacterized phage protein gp47/JayE	353
644378412	132	37.14	18	122	23	117	5.0e-12	63.6	COG4381	Mu-like prophage protein gp46	135
644378413	194	32.63	1	185	14	203	1.0e-32	132	COG4384	Mu-like prophage protein gp45	203
644378414	375	31.68	3	369	6	382	2.0e-63	236	COG4379	Mu-like prophage tail protein gpP	386
644378415	410	22.8	1	402	4	443	8.0e-28	118	COG4228	Mu-like prophage DNA circulation protein	451
644378419	81	35.8	3	81	2	82	3.0e-08	49.9	COG2336	Antitoxin component of the MazEF toxin-antitoxin module	82
644378421	493	44.9	4	493	2	487	4.0e-125	442	COG4386	Mu-like prophage tail sheath protein gpL	487
644378432	617	17.65	31	472	23	462	3.0e-13	70.8	COG3593	Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains	581
644378439	127	49.6	1	124	2	126	7.0e-20	89.5	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
644378440	302	31.97	3	294	1	290	3.0e-28	119	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378441	310	24.78	78	303	64	277	3.0e-09	56	COG5006	Threonine/homoserine efflux transporter RhtA	292
644378442	877	57.62	1	877	6	879	0.0e+00	1152	COG0013	Alanyl-tRNA synthetase	879
644378443	152	38.71	54	146	2	93	2.0e-12	65	COG4891	Uncharacterized protein	93
644378444	151	36.31	1	151	18	174	2.0e-21	95.4	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
644378445	351	64.66	6	285	5	279	4.0e-90	324	COG0468	RecA/RadA recombinase	279
644378448	343	39.09	1	324	11	336	4.0e-74	271	COG2951	Membrane-bound lytic murein transglycosylase B	343
644378449	657	45.98	22	467	1	447	0.0e+00	469	COG2812	DNA polymerase III, gamma/tau subunits	515
644378450	112	53.21	1	109	1	105	5.0e-25	106	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
644378451	199	56.06	1	198	1	198	1.0e-77	282	COG0353	Recombinational DNA repair protein RecR	198
644378452	210	37.75	5	208	6	203	5.0e-35	141	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
644378453	375	35.1	1	374	12	407	6.0e-77	281	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644378454	117	35.29	1	117	1	117	5.0e-28	116	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
644378455	384	49.28	1	344	5	349	8.0e-116	410	COG5008	Tfp pilus assembly protein, ATPase PilU	375
644378456	559	37.3	13	557	1	528	0.0e+00	467	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644378457	141	45.89	1	141	8	153	1.0e-33	135	COG0779	Ribosome maturation factor RimP	153
644378458	493	52.04	159	353	1	190	2.0e-48	186	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
644378459	953	64.36	453	953	3	507	0.0e+00	685	COG0532	Translation initiation factor IF-2, a GTPase	509
644378460	132	48.21	9	118	5	116	1.0e-30	125	COG0858	Ribosome-binding factor A	118
644378461	307	38	1	300	4	269	2.0e-63	235	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
644378462	89	60.67	1	89	1	89	1.0e-27	114	COG0184	Ribosomal protein S15P/S13E	89
644378463	719	62.54	1	700	1	692	0.0e+00	952	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
644378465	419	25.19	21	418	9	396	1.0e-17	84.6	COG3213	Uncharacterized protein involved in response to NO	396
644378466	226	29.11	9	216	1	213	7.0e-30	124	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
644378467	404	52.84	1	404	4	403	0.0e+00	540	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
644378468	344	45.43	1	336	1	336	5.0e-95	341	COG3138	Arginine/ornithine N-succinyltransferase beta subunit	336
644378469	344	60.06	1	338	1	336	1.0e-129	456	COG3138	Arginine/ornithine N-succinyltransferase beta subunit	336
644378470	486	39.17	6	458	5	455	2.0e-104	373	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644378471	449	63.68	3	448	2	441	0.0e+00	650	COG3724	Succinylarginine dihydrolase	442
644378472	309	45.72	1	304	3	293	3.0e-55	208	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
644378473	361	41.92	20	353	7	312	2.0e-52	200	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
644378474	256	58.17	4	253	3	250	2.0e-90	325	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
644378475	236	58.65	1	236	1	237	9.0e-92	329	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
644378476	267	29.24	20	254	1	223	1.0e-19	90.6	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
644378477	250	30.95	1	245	2	252	2.0e-47	182	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
644378478	261	53.46	42	254	16	230	3.0e-63	235	COG2356	Endonuclease I	237
644378479	295	48.97	2	292	1	285	2.0e-74	272	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
644378480	374	32.82	17	210	14	198	2.0e-30	126	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
644378481	260	43.85	1	257	1	257	2.0e-48	186	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
644378482	386	47.45	1	381	1	391	1.0e-92	333	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644378483	500	40.21	8	483	1	469	2.0e-119	422	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644378484	283	51.06	1	283	1	284	2.0e-91	329	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
644378485	749	23.74	234	482	14	264	2.0e-18	88.5	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
644378486	304	34.94	1	304	9	261	2.0e-58	219	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
644378487	478	64.44	19	437	1	418	0.0e+00	639	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
644378489	281	54.35	2	277	1	274	5.0e-101	360	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
644378490	253	37.5	2	223	78	287	8.0e-49	187	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644378491	401	22.92	16	392	3	384	2.0e-12	67.2	COG0475	Kef-type K+ transport system, membrane component KefB	397
644378492	371	41.32	11	371	2	364	6.0e-100	357	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
644378493	262	36.6	2	234	1	219	6.0e-43	167	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
644378494	242	44.05	2	240	1	237	7.0e-57	213	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
644378496	132	51.92	7	110	16	119	7.0e-32	129	COG4273	Uncharacterized protein, contains metal-binding DGC domain	135
644378497	393	18.18	47	392	36	404	1.0e-17	84.5	COG1524	Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily	450
644378498	115	31.53	5	112	9	114	2.0e-08	51.5	COG0727	Fe-S-cluster containining protein	132
644378499	394	44.67	6	394	4	392	6.0e-79	288	COG0183	Acetyl-CoA acetyltransferase	392
644378500	360	26	11	359	13	353	2.0e-24	106	COG0628	Predicted PurR-regulated permease PerM	355
644378501	596	41.41	16	596	8	569	0.0e+00	482	COG4232	Thiol:disulfide interchange protein	569
644378502	269	20.99	4	260	26	282	7.0e-11	61.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644378503	264	42.51	2	263	1	286	6.0e-71	260	COG1469	GTP cyclohydrolase FolE2	289
644378504	431	33.33	47	426	1	371	4.0e-36	146	COG3174	Uncharacterized membrane protein, DUF4010 family	371
644378505	618	63.9	1	618	1	625	0.0e+00	941	COG1154	Deoxyxylulose-5-phosphate synthase	627
644378506	298	34.73	4	298	1	322	8.0e-61	227	COG0142	Geranylgeranyl pyrophosphate synthase	322
644378507	77	47.54	3	63	4	64	5.0e-09	52.6	COG1722	Exonuclease VII small subunit	81
644378511	262	30.89	138	259	1	123	1.0e-18	86.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644378512	1444	39.34	1	853	2	788	0.0e+00	722	COG1201	Lhr-like helicase	814
644378513	136	28.97	29	133	29	135	3.0e-11	61.2	COG0071	Molecular chaperone IbpA, HSP20 family	146
644378514	809	48.5	38	797	6	773	0.0e+00	918	COG0466	ATP-dependent Lon protease, bacterial type	782
644378515	233	38.37	1	233	1	244	2.0e-47	182	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
644378517	731	22	56	692	43	626	1.0e-19	92.4	COG1289	Uncharacterized membrane protein YccC	674
644378518	512	25.41	1	481	1	432	3.0e-45	176	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
644378519	271	23.19	32	230	2	194	4.0e-13	68.9	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
644378520	430	32.12	96	406	64	386	1.0e-56	214	COG1306	Uncharacterized protein	400
644378521	778	40.86	391	773	16	409	1.0e-104	374	COG3876	Uncharacterized conserved protein YbbC, DUF1343 family	409
644378522	376	28.07	87	370	15	282	1.0e-17	84.6	COG0842	ABC-type multidrug transport system, permease component	286
644378523	913	46.47	272	510	4	244	5.0e-70	259	COG1131	ABC-type multidrug transport system, ATPase component	293
644378524	386	29.65	7	322	14	289	2.0e-24	107	COG1566	Multidrug resistance efflux pump	352
644378525	221	40.09	1	221	9	229	6.0e-34	137	COG1802	DNA-binding transcriptional regulator, GntR family	230
644378526	445	36.2	3	441	4	440	1.0e-116	413	COG0174	Glutamine synthetase	443
644378527	452	33.33	26	452	3	430	2.0e-106	379	COG0001	Glutamate-1-semialdehyde aminotransferase	432
644378528	365	51.46	5	359	6	376	2.0e-107	382	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
644378529	446	50.12	4	414	3	409	3.0e-96	345	COG1301	Na+/H+-dicarboxylate symporter	415
644378530	308	32.78	1	297	1	297	1.0e-23	103	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378531	467	18.14	1	460	6	472	8.0e-30	125	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
644378533	297	31.1	1	277	1	275	2.0e-30	126	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644378535	531	27.8	5	481	3	414	4.0e-54	206	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
644378536	303	36.67	3	298	1	296	7.0e-36	144	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378537	330	37.8	1	327	1	315	8.0e-64	237	COG0385	Predicted Na+-dependent transporter	319
644378539	443	30.4	125	437	10	334	5.0e-34	139	COG0642	Signal transduction histidine kinase	336
644378540	241	47.01	5	237	2	229	2.0e-61	229	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644378544	324	43.87	4	324	3	326	6.0e-73	268	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
644378545	197	39.25	4	187	2	187	7.0e-44	170	COG3150	Predicted esterase YcpF, UPF0227 family	191
644378547	255	20.08	7	250	16	262	2.0e-12	66.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644378548	1115	56.51	331	1096	1	734	0.0e+00	984	COG1410	Methionine synthase I, cobalamin-binding domain	842
644378550	380	57.95	1	379	6	394	0.0e+00	493	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
644378551	453	52.29	3	307	2	298	2.0e-109	389	COG0031	Cysteine synthase	300
644378552	203	24.56	21	174	45	210	2.0e-10	59.6	COG0775	Nucleoside phosphorylase	234
644378553	71	61.43	1	70	1	70	4.0e-15	73	COG2841	Uncharacterized conserved protein YdcH, DUF465 family	72
644378554	261	21.93	14	258	10	275	9.0e-09	54.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644378555	501	37.55	30	499	3	453	1.0e-112	400	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644378556	468	46.52	1	444	4	446	6.0e-122	431	COG1113	L-asparagine transporter and related permeases	462
644378558	442	19.39	29	441	25	445	3.0e-21	96.8	COG2271	Sugar phosphate permease	448
644378559	618	35.85	35	603	12	567	1.0e-115	410	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
644378562	538	43.8	5	531	1	480	0.0e+00	525	COG2509	Uncharacterized FAD-dependent dehydrogenase	486
644378563	586	54.5	43	586	4	539	0.0e+00	650	COG0405	Gamma-glutamyltranspeptidase	539
644378564	188	33.93	15	70	5	60	2.0e-07	49.4	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
644378565	298	25.59	46	297	39	286	5.0e-07	48.7	COG5006	Threonine/homoserine efflux transporter RhtA	292
644378566	178	35.14	22	165	32	172	5.0e-19	87.3	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
644378567	168	26.04	6	162	56	220	6.0e-20	90.5	COG1451	Predicted metal-dependent hydrolase	223
644378569	376	18.53	6	365	3	335	4.0e-07	49.6	COG3203	Outer membrane protein (porin)	354
644378571	327	32.74	1	326	2	330	4.0e-55	208	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
644378572	444	35.23	1	444	3	456	1.0e-78	287	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644378573	453	34.77	13	405	1	370	2.0e-61	230	COG0348	Polyferredoxin	386
644378574	239	34.96	7	230	6	230	6.0e-34	137	COG1802	DNA-binding transcriptional regulator, GntR family	230
644378575	490	38.58	18	475	23	483	4.0e-113	402	COG1953	Cytosine/uracil/thiamine/allantoin permease	497
644378576	181	51.38	1	181	1	181	2.0e-58	218	COG4681	Uncharacterized conserved protein YaeQ, suppresses RfaH defect	181
644378577	295	35.14	1	292	3	297	4.0e-38	151	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378578	135	35.04	1	135	6	140	4.0e-07	47.3	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
644378579	260	39.39	1	256	6	268	2.0e-57	216	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
644378580	562	40.2	1	484	26	513	5.0e-120	425	COG0513	Superfamily II DNA and RNA helicase	513
644378582	240	39.5	1	235	3	227	1.0e-33	136	COG5446	Uncharacterized membrane protein, predicted cobalt tansporter CbtA	233
644378583	628	19.33	18	564	6	585	3.0e-42	166	COG0557	Exoribonuclease R	706
644378584	254	38.58	1	254	1	253	1.0e-66	246	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
644378585	494	58.42	5	491	7	499	0.0e+00	711	COG0554	Glycerol kinase	499
644378587	460	63.88	7	460	6	459	0.0e+00	651	COG0165	Argininosuccinate lyase	459
644378591	177	31.64	2	174	6	180	2.0e-17	82.4	COG4970	Tfp pilus assembly protein FimT	181
644378592	142	42.65	15	140	6	139	2.0e-18	85.1	COG4968	Tfp pilus assembly protein PilE	139
644378593	901	47.38	4	901	3	910	0.0e+00	929	COG2352	Phosphoenolpyruvate carboxylase	910
644378594	311	57.38	1	304	1	305	1.0e-108	386	COG0181	Porphobilinogen deaminase	307
644378595	245	36.95	5	244	1	247	3.0e-33	135	COG1587	Uroporphyrinogen-III synthase	248
644378596	346	30.5	20	336	37	352	1.0e-44	174	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
644378597	402	32.67	1	401	1	395	2.0e-52	199	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
644378598	236	39	1	232	3	241	2.0e-56	212	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
644378600	192	26.06	1	186	3	189	2.0e-07	49.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644378601	404	41.54	13	394	5	390	4.0e-105	375	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
644378602	299	52.17	5	299	1	298	6.0e-101	360	COG4989	Predicted oxidoreductase	298
644378603	369	51.52	1	363	1	338	2.0e-124	438	COG3839	ABC-type sugar transport system, ATPase component	338
644378604	285	36.14	1	284	3	281	1.0e-57	216	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
644378605	313	39.04	22	312	2	293	2.0e-57	215	COG1175	ABC-type sugar transport system, permease component	295
644378606	414	27.06	1	412	7	427	2.0e-27	117	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
644378607	478	34.73	170	477	37	336	1.0e-42	168	COG0642	Signal transduction histidine kinase	336
644378608	227	41.74	1	224	1	229	7.0e-48	183	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644378609	347	45.45	3	344	14	349	6.0e-99	354	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
644378610	625	51.54	1	580	5	579	0.0e+00	568	COG0443	Molecular chaperone DnaK (HSP70)	579
644378612	820	35.82	205	785	63	646	3.0e-123	436	COG1067	Predicted ATP-dependent protease	647
644378613	208	57	1	206	4	209	1.0e-57	216	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
644378614	611	40.36	9	604	4	571	0.0e+00	621	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
644378615	490	53.83	9	489	6	483	0.0e+00	656	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
644378616	225	31.6	1	224	1	229	7.0e-45	173	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
644378617	327	55.66	4	319	1	318	2.0e-109	389	COG0837	Glucokinase	320
644378618	283	42.03	1	275	5	280	1.0e-66	246	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
644378619	549	53.24	43	535	1	445	0.0e+00	541	COG0166	Glucose-6-phosphate isomerase	446
644378620	107	55.67	4	100	6	101	2.0e-23	100	COG3695	Alkylated DNA nucleotide flippase Atl1, participates in nucleotide excision repair, Ada-like DNA-binding domain	103
644378621	216	36.11	1	209	10	225	2.0e-32	132	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644378622	674	25.4	355	657	69	365	1.0e-25	112	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
644378628	414	32.56	11	414	16	429	5.0e-59	222	COG4580	Maltoporin (phage lambda and maltose receptor)	429
644378629	94	49.35	1	77	3	79	2.0e-22	97.3	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
644378630	380	32.83	131	379	24	281	1.0e-24	107	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
644378631	674	25.2	21	647	1	478	2.0e-63	237	COG1333	Cytochrome c biogenesis protein ResB	478
644378632	205	46.77	4	127	3	120	7.0e-24	103	COG2863	Cytochrome c553	121
644378633	207	45	1	197	1	200	1.0e-62	233	COG0218	GTP-binding protein EngB required for normal cell division	200
644378635	154	60.65	1	154	2	155	2.0e-64	238	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
644378636	236	39.82	13	231	7	223	1.0e-35	143	COG1040	Predicted amidophosphoribosyltransferases	225
644378637	327	56.96	13	326	6	319	1.0e-115	410	COG0502	Biotin synthase or related enzyme	335
644378638	382	48.68	4	378	5	384	3.0e-112	398	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
644378639	957	34.49	472	951	175	649	5.0e-84	306	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
644378641	254	31.6	4	253	14	282	8.0e-19	87.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644378642	304	23.74	8	202	9	219	1.0e-17	83.8	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
644378643	303	36.84	36	288	4	288	1.0e-47	183	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
644378644	218	32.85	2	199	1	200	4.0e-19	88.3	COG0625	Glutathione S-transferase	211
644378645	359	44.9	6	337	1	341	5.0e-84	304	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
644378646	114	63.74	17	107	2	92	1.0e-35	141	COG3526	Predicted selenoprotein, Rdx family	99
644378647	920	47.45	653	907	1	253	7.0e-75	276	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644378648	152	40.85	4	145	1	141	3.0e-29	121	COG2847	Copper(I)-binding protein	151
644378649	215	39.71	6	214	3	202	3.0e-32	131	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
644378650	284	29.41	160	277	8	126	5.0e-16	78.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644378651	233	39.3	5	233	10	237	2.0e-34	138	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
644378652	104	45.19	1	104	4	107	3.0e-13	66.7	COG4392	Branched-chain amino acid transport protein	107
644378654	364	41.82	5	364	2	373	5.0e-75	275	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
644378655	665	37.6	5	619	1	589	2.0e-126	446	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
644378656	167	37.04	7	167	1	162	4.0e-16	77.5	COG2891	Cell shape-determining protein MreD	167
644378657	295	31.43	7	283	1	279	3.0e-48	185	COG1792	Cell shape-determining protein MreC	284
644378658	347	67.74	5	343	1	339	0.0e+00	463	COG1077	Actin-like ATPase involved in cell morphogenesis	342
644378659	95	45.26	1	95	1	95	2.0e-22	97.6	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
644378660	483	54.69	1	481	4	474	0.0e+00	522	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
644378661	475	56.69	1	475	4	481	0.0e+00	671	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
644378662	148	40.88	1	137	1	136	3.0e-33	134	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
644378663	320	52.88	4	312	3	313	1.0e-113	403	COG0275	16S rRNA C1402 N4-methylase RsmH	314
644378664	90	38.37	1	86	20	105	3.0e-16	76.5	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
644378665	582	37.91	8	564	1	599	1.0e-119	423	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
644378666	497	43.42	16	488	4	475	0.0e+00	461	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
644378667	453	48.24	1	449	2	451	2.0e-122	433	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
644378668	361	45.16	27	361	6	316	4.0e-58	218	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
644378669	455	46.26	1	451	3	448	2.0e-127	449	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
644378670	385	41.6	15	385	14	381	1.0e-80	293	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
644378671	350	45.63	1	348	4	355	2.0e-90	326	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
644378672	463	53.98	1	462	3	456	0.0e+00	552	COG0773	UDP-N-acetylmuramate-alanine ligase	459
644378673	303	44.94	3	300	1	316	1.0e-82	299	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
644378674	242	33.47	1	229	24	256	1.0e-33	136	COG1589	Cell division septal protein FtsQ	269
644378675	413	52.28	5	413	2	418	0.0e+00	471	COG0849	Cell division ATPase FtsA	418
644378676	396	53.85	11	334	7	328	8.0e-95	341	COG0206	Cell division GTPase FtsZ	338
644378677	304	60.2	1	299	1	297	6.0e-126	443	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
644378679	157	61.15	1	157	1	156	9.0e-58	215	COG0315	Molybdenum cofactor biosynthesis enzyme	157
644378680	233	40.2	31	227	21	217	1.0e-43	169	COG4318	Uncharacterized protein	221
644378681	295	22.48	67	283	71	285	1.0e-06	47.5	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
644378683	259	37.5	1	258	1	270	2.0e-48	186	COG3332	Uncharacterized conserved protein, contains NRDE domain	270
644378684	76	38.16	1	76	2	77	1.0e-16	78	COG0425	TusA-related sulfurtransferase	78
644378685	342	67.16	1	341	3	343	0.0e+00	546	COG0418	Dihydroorotase	344
644378686	364	27.5	8	355	13	372	2.0e-13	70.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644378687	1010	37.57	2	1005	1	1008	0.0e+00	837	COG0841	Multidrug efflux pump subunit AcrB	1009
644378688	248	19.54	1	241	5	262	2.0e-09	56.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644378689	260	51.17	10	260	11	261	1.0e-88	319	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
644378690	293	37.2	1	287	1	289	2.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378693	342	43.6	3	341	1	342	8.0e-83	301	COG2008	Threonine aldolase	342
644378695	676	44.05	5	675	4	648	0.0e+00	605	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
644378698	174	47.78	1	169	35	212	1.0e-32	132	COG3132	Uncharacterized conserved protein YceH, UPF0502 family	215
644378700	257	45.42	2	252	3	243	1.0e-63	236	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
644378702	449	40.88	7	445	3	440	3.0e-108	385	COG0174	Glutamine synthetase	443
644378704	715	45.85	6	634	1	648	0.0e+00	570	COG0210	Superfamily I DNA or RNA helicase	655
644378705	280	30	13	254	21	273	8.0e-26	111	COG3491	Isopenicillin N synthase and related dioxygenases	322
644378706	260	59.44	79	258	5	184	3.0e-69	255	COG1045	Serine acetyltransferase	194
644378707	498	46.28	17	498	2	483	0.0e+00	479	COG1530	Ribonuclease G or E	487
644378708	198	50.26	8	195	5	189	1.0e-56	212	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
644378709	333	26.42	74	319	2	226	3.0e-16	79.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644378710	310	33.22	19	305	1	286	5.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378711	270	25.57	15	268	34	270	2.0e-32	132	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
644378713	207	22.79	1	206	2	216	1.0e-22	99.8	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
644378715	419	60.91	3	419	1	417	0.0e+00	607	COG0014	Gamma-glutamyl phosphate reductase	417
644378716	633	38.92	45	616	1	528	0.0e+00	536	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
644378718	540	28.98	160	539	32	407	3.0e-39	156	COG0840	Methyl-accepting chemotaxis protein	408
644378719	427	37.17	7	422	11	415	2.0e-71	263	COG4949	Uncharacterized membrane-anchored protein	424
644378720	543	30.17	133	543	1	408	1.0e-42	168	COG0840	Methyl-accepting chemotaxis protein	408
644378721	143	21.74	8	132	15	152	5.0e-06	43.9	COG4701	Uncharacterized protein	162
644378722	905	58.75	2	898	1	822	0.0e+00	1097	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
644378723	257	34.62	1	255	4	251	7.0e-35	141	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644378724	306	46.51	1	300	1	300	2.0e-79	289	COG3781	Predicted membrane chloride channel, bestrophin family	306
644378725	467	64.29	1	462	2	463	0.0e+00	716	COG1027	Aspartate ammonia-lyase	471
644378726	303	28.57	1	299	1	290	1.0e-25	110	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378728	507	52.02	332	503	2	173	8.0e-43	168	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644378730	221	41.26	1	221	1	218	7.0e-49	187	COG4122	Predicted O-methyltransferase YrrM	219
644378731	125	38.28	1	125	13	136	4.0e-19	86.8	COG0848	Biopolymer transport protein ExbD	137
644378733	428	39.62	9	425	2	424	1.0e-88	320	COG0823	Periplasmic component of the Tol biopolymer transport system	425
644378734	178	30.11	7	175	12	187	3.0e-29	121	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
644378735	258	28.57	1	258	2	261	2.0e-26	113	COG1729	Periplasmic TolA-binding protein (function unknown)	262
644378736	162	62.96	1	162	2	161	3.0e-56	210	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
644378737	376	51.35	8	375	2	367	3.0e-122	431	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
644378738	292	37.1	12	291	4	246	1.0e-68	253	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
644378739	193	33.87	6	190	3	186	6.0e-24	103	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644378741	260	36.65	1	249	57	290	3.0e-35	142	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
644378742	810	24.32	5	291	20	308	8.0e-21	96.5	COG3447	Integral membrane sensor domain MASE1	308
644378743	673	43.21	4	356	3	362	2.0e-108	387	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
644378744	327	29.13	4	307	3	254	2.0e-26	113	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
644378745	772	59.84	12	772	19	780	0.0e+00	1009	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
644378746	597	48.26	107	587	9	492	0.0e+00	505	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
644378747	778	51.05	113	773	65	709	0.0e+00	713	COG2217	Cation transport ATPase	713
644378750	301	27.49	6	290	5	288	3.0e-37	149	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378751	271	58.59	10	265	7	259	1.0e-93	336	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
644378752	478	48.43	1	470	1	477	0.0e+00	559	COG0469	Pyruvate kinase	477
644378753	138	43.38	1	131	2	137	2.0e-24	104	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
644378757	294	52.46	4	285	3	286	5.0e-86	311	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
644378758	259	61.33	1	256	1	256	5.0e-109	387	COG3622	Hydroxypyruvate isomerase	260
644378759	591	83.39	1	590	1	590	0.0e+00	1085	COG3960	Glyoxylate carboligase	592
644378760	247	50.87	1	229	1	230	2.0e-61	229	COG4126	Asp/Glu/hydantoin racemase	230
644378761	489	42	18	484	20	485	2.0e-109	389	COG1953	Cytosine/uracil/thiamine/allantoin permease	497
644378762	311	23.13	5	305	1	267	1.0e-27	117	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
644378764	167	59.09	6	158	4	156	9.0e-54	202	COG3194	Ureidoglycolate hydrolase (allantoin degradation)	168
644378765	345	61.21	15	342	9	334	3.0e-126	445	COG4266	Allantoicase	334
644378766	443	49.04	3	413	2	406	2.0e-94	339	COG1301	Na+/H+-dicarboxylate symporter	415
644378768	223	29.11	1	212	9	216	1.0e-18	86.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
644378769	397	46.32	1	395	1	404	5.0e-114	404	COG3748	Uncharacterized membrane protein	407
644378770	117	64.1	1	117	8	124	2.0e-45	174	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
644378771	172	47.65	8	172	5	174	2.0e-34	138	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
644378772	248	31.12	8	246	7	241	2.0e-32	132	COG2186	DNA-binding transcriptional regulator, FadR family	241
644378773	312	31.68	7	311	4	324	6.0e-45	174	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
644378774	414	25.41	1	414	2	382	1.0e-31	131	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644378775	372	36.03	16	365	3	357	3.0e-58	219	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
644378776	164	32.76	33	147	15	127	1.0e-12	66.5	COG0526	Thiol-disulfide isomerase or thioredoxin	127
644378777	314	22.81	2	308	1	311	1.0e-34	140	COG0524	Sugar or nucleoside kinase, ribokinase family	311
644378779	314	39.32	1	311	1	314	3.0e-63	235	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
644378780	355	36.42	9	340	4	333	2.0e-55	210	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
644378781	125	54.24	7	124	1	118	9.0e-30	122	COG0818	Diacylglycerol kinase	123
644378783	763	50.79	4	569	2	555	0.0e+00	650	COG0550	DNA topoisomerase IA	570
644378784	152	38.85	1	151	1	155	4.0e-29	120	COG2922	Uncharacterized conserved protein Smg, DUF494 family	157
644378785	366	42.74	1	365	2	350	1.0e-91	330	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
644378787	167	52.38	1	164	1	168	5.0e-57	213	COG0242	Peptide deformylase	168
644378788	306	52.29	1	302	2	307	2.0e-101	362	COG0223	Methionyl-tRNA formyltransferase	307
644378789	284	34.88	9	281	33	298	6.0e-40	158	COG0501	Zn-dependent protease with chaperone function	302
644378790	416	36.65	93	416	4	354	2.0e-72	266	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
644378792	702	34.59	1	701	7	710	0.0e+00	488	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
644378793	423	35.09	1	414	2	456	2.0e-93	336	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644378794	256	53.36	3	249	2	253	7.0e-69	253	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
644378795	163	24.34	20	159	2	151	2.0e-14	71.8	COG1225	Peroxiredoxin	157
644378796	148	36.57	1	133	4	135	1.0e-23	102	COG0824	Acyl-CoA thioesterase FadM	137
644378798	294	16.54	17	288	2	244	8.0e-10	57.8	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
644378799	154	50.33	1	153	4	156	8.0e-48	182	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
644378800	108	38	11	108	2	99	7.0e-17	78.8	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
644378802	114	53.4	4	106	1	103	1.0e-33	135	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
644378804	351	44.35	5	348	12	347	6.0e-85	307	COG0687	Spermidine/putrescine-binding periplasmic protein	363
644378805	178	19.63	3	159	5	158	3.0e-07	48.4	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
644378806	211	35.75	1	202	1	205	8.0e-40	157	COG3647	Uncharacterized membrane protein YjdF	205
644378807	654	46.13	1	651	2	631	0.0e+00	766	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
644378808	199	25.82	1	154	6	186	8.0e-10	57.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644378809	293	37.33	7	293	6	293	3.0e-38	152	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378810	296	29.45	6	293	1	292	2.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378811	184	33.14	12	177	9	177	9.0e-23	99	COG2059	Chromate transport protein ChrA	195
644378812	173	33.91	3	173	6	179	3.0e-23	101	COG2059	Chromate transport protein ChrA	195
644378813	355	53.26	1	351	2	352	2.0e-125	441	COG0407	Uroporphyrinogen-III decarboxylase	352
644378814	725	44.34	7	725	4	730	0.0e+00	710	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
644378815	477	33.26	2	450	8	463	1.0e-68	254	COG2027	D-alanyl-D-alanine carboxypeptidase	470
644378816	85	57.5	2	80	1	80	4.0e-20	89.6	COG0695	Glutaredoxin	80
644378817	150	50	3	150	5	152	6.0e-44	170	COG1952	Preprotein translocase subunit SecB	157
644378818	148	22.22	1	147	4	163	4.0e-07	47.3	COG3807	SH3-like domain	171
644378819	334	51.67	1	328	2	329	4.0e-108	384	COG0240	Glycerol-3-phosphate dehydrogenase	329
644378820	172	33.77	1	151	1	147	3.0e-24	104	COG2077	Peroxiredoxin	158
644378822	298	42.9	1	294	2	299	2.0e-79	289	COG2264	Ribosomal protein L11 methylase PrmA	300
644378823	452	65.18	1	446	1	447	0.0e+00	620	COG0439	Biotin carboxylase	449
644378824	151	45.89	6	151	1	139	2.0e-28	118	COG0511	Biotin carboxyl carrier protein	140
644378825	149	56.16	4	149	2	146	6.0e-53	199	COG0757	3-dehydroquinate dehydratase	146
644378826	355	58.21	15	355	1	347	0.0e+00	479	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
644378827	122	61.21	7	122	2	117	3.0e-43	167	COG3536	Uncharacterized conserved protein, DUF971 family	120
644378828	244	58.16	9	244	1	238	3.0e-81	294	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
644378829	207	49.76	3	205	2	208	9.0e-27	113	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644378830	192	30.89	7	189	14	204	3.0e-23	101	COG3165	Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain	204
644378831	508	47.04	2	502	6	505	0.0e+00	492	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
644378832	126	32.63	11	105	19	113	6.0e-12	63.1	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
644378833	121	46.28	1	119	5	125	1.0e-31	128	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
644378834	409	39.51	8	403	1	393	3.0e-98	352	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
644378835	436	49.25	1	324	1	333	2.0e-102	366	COG0460	Homoserine dehydrogenase	333
644378836	468	33.19	1	465	1	410	3.0e-100	359	COG0498	Threonine synthase	411
644378837	228	31.82	10	227	2	219	2.0e-25	109	COG1261	Flagella basal body P-ring formation protein FlgA	220
644378839	154	21.33	5	152	3	145	1.0e-05	42.3	COG3418	Flagellar biosynthesis/type III secretory pathway chaperone	146
644378840	306	32.81	1	306	8	319	8.0e-39	154	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
644378841	456	46.75	1	409	29	437	9.0e-118	417	COG0513	Superfamily II DNA and RNA helicase	513
644378843	460	47.1	33	452	32	459	2.0e-126	445	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
644378845	410	43.05	1	405	1	447	3.0e-116	412	COG0527	Aspartokinase	447
644378850	393	23.01	13	366	10	349	1.0e-13	71.4	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
644378853	290	26.46	5	290	1	291	2.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378854	379	43.33	1	352	1	355	3.0e-95	342	COG0787	Alanine racemase	360
644378855	254	32.51	18	252	30	269	1.0e-36	146	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644378857	555	48.34	6	537	1	530	0.0e+00	566	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644378858	159	39.13	1	159	1	160	3.0e-17	81.4	COG2839	Uncharacterized conserved protein YqgC, DUF456 family	160
644378859	684	52.77	1	681	4	685	0.0e+00	915	COG0855	Polyphosphate kinase	696
644378860	91	53.33	1	90	1	90	2.0e-34	137	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
644378861	436	36.43	21	285	1	265	3.0e-57	216	COG0548	Acetylglutamate kinase	265
644378862	472	43.53	3	414	1	406	2.0e-100	360	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
644378863	437	31.18	4	435	12	417	2.0e-52	200	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
644378864	506	56.13	5	504	4	508	0.0e+00	638	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
644378865	98	29.79	1	93	5	98	1.0e-08	51.3	COG0640	DNA-binding transcriptional regulator, ArsR family	110
644378867	451	51.26	6	440	1	434	0.0e+00	463	COG1570	Exonuclease VII, large subunit	440
644378868	209	30.15	5	200	14	211	3.0e-31	128	COG0811	Biopolymer transport protein ExbB/TolQ	216
644378869	142	34.31	1	135	1	133	4.0e-23	100	COG0848	Biopolymer transport protein ExbD	137
644378870	336	49.4	4	327	5	325	8.0e-86	310	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
644378871	60	55.93	1	59	1	59	3.0e-15	73.3	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
644378872	258	57.14	5	256	4	247	1.0e-90	326	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
644378873	217	44.34	1	217	1	178	8.0e-47	180	COG0563	Adenylate kinase or related kinase	178
644378874	506	23.01	145	505	1	332	5.0e-26	112	COG0642	Signal transduction histidine kinase	336
644378876	490	44.53	218	482	17	282	4.0e-50	192	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
644378877	211	46.7	7	203	5	189	5.0e-67	247	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
644378878	184	32.45	20	170	12	161	1.0e-21	96.5	COG4769	Uncharacterized membrane protein	181
644378880	280	49.83	1	279	1	286	3.0e-92	331	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
644378881	318	43.45	2	313	1	307	3.0e-86	311	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
644378882	153	34.9	3	149	1	149	6.0e-31	127	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
644378883	109	46.46	1	97	1	99	7.0e-23	98.8	COG1544	Ribosome-associated translation inhibitor RaiA	110
644378884	466	46.91	1	466	1	443	2.0e-127	449	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
644378885	242	69.71	4	242	3	243	5.0e-105	374	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
644378886	173	38.15	1	171	1	167	4.0e-26	111	COG1934	Lipopolysaccharide export system protein LptA	173
644378887	187	24.18	4	185	2	182	2.0e-24	105	COG3117	Lipopolysaccharide export system protein LptC	188
644378888	174	54.76	6	173	3	170	7.0e-59	220	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
644378889	326	60	10	208	2	201	3.0e-65	242	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
644378890	655	40.95	1	392	5	397	9.0e-61	228	COG0475	Kef-type K+ transport system, membrane component KefB	397
644378891	717	18.95	10	640	4	581	5.0e-22	100	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
644378893	243	25.23	11	220	1	214	6.0e-22	98	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
644378894	302	36.63	1	300	1	297	5.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378895	497	50.4	1	496	1	501	0.0e+00	563	COG0427	Acyl-CoA hydrolase	501
644378896	271	45	35	254	1	218	3.0e-51	195	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
644378897	310	58.5	1	306	1	306	6.0e-117	413	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
644378898	381	44.39	150	372	1	210	1.0e-41	163	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
644378899	308	42.72	3	304	8	300	1.0e-83	303	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
644378900	105	29.63	6	85	9	89	4.0e-08	49.8	COG1993	PII-like signaling protein	109
644378902	611	65.26	1	565	1	557	0.0e+00	800	COG0480	Translation elongation factor EF-G, a GTPase	697
644378904	335	32.84	4	328	21	351	1.0e-57	217	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
644378905	185	32.77	10	179	10	180	2.0e-17	82.3	COG3172	Nicotinamide riboside kinase	187
644378906	73	39.73	1	73	1	73	3.0e-17	79.9	COG2501	Ribosome-associated protein YbcJ, S4-like RNA binding protein	73
644378908	284	45.06	4	255	4	252	2.0e-49	189	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
644378909	206	44.66	2	205	1	205	3.0e-58	218	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
644378910	212	35.57	7	195	13	201	8.0e-14	70.8	COG1994	Zn-dependent protease (includes SpoIVFB)	230
644378912	284	41	50	282	1	239	5.0e-45	175	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
644378913	207	47.19	5	181	4	179	3.0e-43	168	COG1386	Chromosome segregation and condensation protein ScpB	184
644378914	497	43.2	246	488	1	247	5.0e-63	235	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
644378915	185	39.87	31	182	1	151	6.0e-32	130	COG0782	Transcription elongation factor, GreA/GreB family	151
644378916	379	41.81	11	296	3	288	1.0e-67	250	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
644378919	173	26.23	8	171	13	186	1.0e-12	66.6	COG3658	Cytochrome b	192
644378920	145	27.88	31	134	14	117	7.0e-10	56.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
644378921	382	45.65	25	381	90	455	1.0e-91	330	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644378922	312	33	1	294	1	287	6.0e-36	144	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378923	87	51.72	1	87	1	85	9.0e-20	88.3	COG0851	Septum formation topological specificity factor MinE	88
644378924	270	65.93	1	270	1	269	8.0e-117	413	COG2894	Septum formation inhibitor-activating ATPase MinD	272
644378925	235	42.54	9	235	2	219	1.0e-41	163	COG0850	Septum formation inhibitor MinC	219
644378928	177	53.14	1	175	1	171	4.0e-56	210	COG0221	Inorganic pyrophosphatase	171
644378929	206	44.39	2	206	1	204	1.0e-55	209	COG2941	Demethoxyubiquinone hydroxylase, CLK1/Coq7/Cat5 family	204
644378930	470	21.49	30	470	1	423	2.0e-43	170	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
644378937	435	31.25	15	371	2	354	9.0e-51	194	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
644378938	476	42.7	9	180	17	194	6.0e-33	135	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
644378939	249	39.2	1	249	1	250	4.0e-65	241	COG1291	Flagellar motor component MotA	266
644378940	248	41.56	22	247	29	247	7.0e-52	197	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
644378941	287	27.52	20	269	4	251	1.0e-19	90.3	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
644378942	479	26.13	1	453	1	395	4.0e-67	249	COG1419	Flagellar biosynthesis GTPase FlhF	407
644378943	694	57.41	8	692	13	696	0.0e+00	852	COG1298	Flagellar biosynthesis pathway, component FlhA	696
644378944	388	41.99	1	361	1	362	3.0e-107	382	COG1377	Flagellar biosynthesis protein FlhB	363
644378945	264	76.32	1	264	3	268	2.0e-126	445	COG0207	Thymidylate synthase	268
644378946	162	52.12	6	161	2	166	1.0e-41	162	COG0262	Dihydrofolate reductase	167
644378947	222	29.22	1	219	9	226	1.0e-23	103	COG1802	DNA-binding transcriptional regulator, GntR family	230
644378948	284	45.36	100	281	9	202	3.0e-41	162	COG1573	Uracil-DNA glycosylase	202
644378949	146	31.52	1	146	11	173	3.0e-15	74.7	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
644378950	227	34.36	1	219	1	219	8.0e-36	143	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
644378951	407	32.35	5	405	2	403	6.0e-69	254	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
644378952	626	39.1	71	608	170	706	4.0e-123	435	COG0643	Chemotaxis protein histidine kinase CheA	716
644378953	249	47.44	37	249	4	217	1.0e-55	210	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
644378955	322	37.28	9	176	3	158	3.0e-29	122	COG0835	Chemotaxis signal transduction protein	165
644378956	314	37.5	5	170	3	163	9.0e-31	127	COG0835	Chemotaxis signal transduction protein	165
644378957	388	27.63	69	388	3	330	7.0e-33	135	COG0642	Signal transduction histidine kinase	336
644378958	107	37.88	4	65	5	68	1.0e-07	48.2	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
644378960	362	48.27	5	359	6	375	4.0e-103	368	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
644378961	128	58.91	1	128	2	130	7.0e-41	159	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
644378962	951	55.68	6	442	1	449	0.0e+00	576	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
644378962	951	60.36	448	923	1	496	0.0e+00	703	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
644378963	541	28.17	72	444	24	393	2.0e-49	190	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644378964	496	38.7	35	493	1	451	3.0e-53	203	COG1538	Outer membrane protein TolC	457
644378966	238	50.91	8	226	1	220	4.0e-80	291	COG1136	ABC-type lipoprotein export system, ATPase component	226
644378967	401	31.9	17	401	1	419	2.0e-34	140	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
644378969	189	41.81	1	177	2	177	1.0e-42	166	COG1704	Uncharacterized conserved protein	185
644378970	287	31.6	4	269	13	276	7.0e-27	114	COG5495	Predicted oxidoreductase, contains short-chain dehydrogenase (SDR) and DUF2520 domains	289
644378971	476	31.91	240	473	3	227	4.0e-43	169	COG1794	Aspartate/glutamate racemase	230
644378972	423	44.15	5	412	7	405	3.0e-91	329	COG1301	Na+/H+-dicarboxylate symporter	415
644378973	307	24.5	1	296	1	287	2.0e-24	107	COG0583	DNA-binding transcriptional regulator, LysR family	297
644378974	234	33.33	1	233	3	225	1.0e-46	179	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
644378975	192	40.41	1	192	3	192	4.0e-47	181	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
644378976	167	25.29	1	162	4	174	3.0e-14	71.5	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
644378977	59	45.61	1	56	1	57	2.0e-12	64.1	COG0333	Ribosomal protein L32	57
644378978	336	54.43	1	325	9	335	3.0e-117	415	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
644378979	319	58.07	1	319	1	322	9.0e-116	410	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
644378980	309	54.05	1	307	2	310	3.0e-91	328	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
644378981	245	49.61	1	243	1	251	2.0e-45	175	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644378982	79	64.1	1	78	3	80	3.0e-12	63.8	COG0236	Acyl carrier protein	80
644378983	413	59.66	3	413	2	411	0.0e+00	487	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644378984	431	37.03	8	431	11	459	2.0e-109	389	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
644378985	270	34.09	9	266	14	276	1.0e-40	160	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
644378987	294	42.05	6	286	4	279	9.0e-65	240	COG0287	Prephenate dehydrogenase	279
644378988	148	55.41	1	148	2	147	5.0e-45	173	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
644378989	142	22.38	9	129	17	157	2.0e-06	45.1	COG4696	Predicted phosphohydrolase, Cof family, HAD superfamily	180
644378990	429	46.5	5	427	6	424	1.0e-129	456	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
644378991	222	51.61	2	216	3	219	7.0e-69	253	COG0283	Cytidylate kinase	222
644378992	567	58.33	6	544	2	532	0.0e+00	593	COG0539	Ribosomal protein S1	541
644378993	104	47.37	1	95	2	91	2.0e-26	110	COG0776	Bacterial nucleoid DNA-binding protein	94
644378994	97	32.05	1	78	22	98	7.0e-07	45.7	COG5416	Uncharacterized integral membrane protein	98
644378995	388	36.86	5	388	2	388	8.0e-97	347	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
644378996	248	52	17	241	14	235	4.0e-65	241	COG0284	Orotidine-5'-phosphate decarboxylase	240
644378997	439	56.37	1	424	1	413	0.0e+00	564	COG1004	UDP-glucose 6-dehydrogenase	414
644378999	191	55.98	5	188	10	181	3.0e-46	178	COG3803	Uncharacterized conserved protein, DUF924 family	182
644379000	331	29.59	1	331	1	311	3.0e-42	165	COG0451	Nucleoside-diphosphate-sugar epimerase	314
644379002	298	50.17	6	294	2	300	1.0e-100	359	COG0031	Cysteine synthase	300
644379003	373	48.19	1	359	9	367	1.0e-126	446	COG1485	Predicted ATPase	367
644379004	187	41.22	1	130	3	131	1.0e-33	136	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
644379005	386	46.52	10	383	4	367	2.0e-106	379	COG4394	Uncharacterized protein	370
644379006	157	29.33	1	148	16	165	6.0e-18	83.8	COG0835	Chemotaxis signal transduction protein	165
644379007	491	37.69	59	255	53	243	2.0e-39	157	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
644379008	207	35.46	65	202	18	158	1.0e-23	103	COG0835	Chemotaxis signal transduction protein	165
644379009	581	28.88	255	581	83	408	2.0e-34	140	COG0840	Methyl-accepting chemotaxis protein	408
644379010	737	31.88	14	599	159	709	3.0e-84	306	COG0643	Chemotaxis protein histidine kinase CheA	716
644379011	338	36.28	1	331	2	339	9.0e-64	237	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
644379014	949	29.89	18	586	109	645	1.0e-99	358	COG0209	Ribonucleotide reductase alpha subunit	696
644379015	216	23.15	4	197	2	195	9.0e-11	60.7	COG0748	Putative heme iron utilization protein	245
644379016	309	31.1	8	302	18	315	2.0e-31	129	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
644379017	192	37.67	1	190	1	215	9.0e-25	106	COG4094	Uncharacterized membrane protein	219
644379018	153	26.06	10	146	12	153	9.0e-16	76.5	COG5615	Uncharacterized membrane protein	161
644379019	637	21.43	213	560	64	407	4.0e-21	96.6	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
644379020	403	23.23	1	396	4	391	5.0e-26	112	COG2814	Predicted arabinose efflux permease, MFS family	394
644379021	414	23.5	8	354	6	300	3.0e-27	116	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
644379022	318	27.3	15	313	3	297	5.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
644379023	446	67.79	1	444	1	443	0.0e+00	683	COG3048	D-serine dehydratase	443
644379025	336	37.64	1	333	3	336	1.0e-77	283	COG4143	ABC-type thiamine transport system, periplasmic component	336
644379026	514	34.36	9	503	14	530	2.0e-56	213	COG1178	ABC-type Fe3+ transport system, permease component	540
644379027	317	38.04	1	315	5	351	6.0e-83	301	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644379028	403	40.34	32	381	2	355	3.0e-59	222	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
644379029	291	25.26	9	291	1	281	3.0e-18	86.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644379030	487	30.77	255	475	1	170	7.0e-34	138	COG0516	IMP dehydrogenase/GMP reductase	170
644379032	601	49	5	600	1	581	0.0e+00	648	COG0322	Excinuclease UvrABC, nuclease subunit	581
644379033	193	45.55	1	190	10	192	2.0e-21	95.5	COG0558	Phosphatidylglycerophosphate synthase	192
644379041	403	44.71	28	401	1	378	2.0e-93	336	COG1929	Glycerate kinase	378
644379042	180	56.07	8	174	3	173	3.0e-46	178	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
644379043	310	61.92	3	303	1	300	1.0e-121	429	COG0031	Cysteine synthase	300
644379045	137	43.08	7	134	2	129	8.0e-33	132	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
644379048	160	61.88	1	160	1	160	4.0e-72	263	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
644379049	189	40.53	3	188	2	180	3.0e-57	214	COG0717	Deoxycytidine triphosphate deaminase	183
644379050	155	48.39	1	155	1	154	2.0e-38	151	COG2193	Bacterioferritin (cytochrome b1)	157
644379051	330	43.33	1	298	1	300	5.0e-85	307	COG2974	DNA recombination-dependent growth factor C	303
644379061	141	60.74	2	136	1	135	2.0e-54	204	COG0105	Nucleoside diphosphate kinase	135
644379062	364	57.67	2	351	1	349	0.0e+00	466	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
644379063	209	37.98	1	208	43	249	4.0e-33	134	COG3063	Tfp pilus assembly protein PilF	250
644379064	295	26.92	17	264	3	284	2.0e-24	106	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
644379065	426	47.54	6	411	1	361	5.0e-127	448	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
644379066	423	48.49	3	423	2	429	0.0e+00	481	COG0124	Histidyl-tRNA synthetase	429
644379067	209	35.41	1	209	1	207	9.0e-31	126	COG2976	Putative negative regulator of RcsB-dependent stress response	207
644379068	380	21.67	1	344	1	348	4.0e-23	102	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
644379069	463	50.11	1	436	2	442	0.0e+00	553	COG1160	Predicted GTPases	444
644379070	86	71.62	3	75	2	75	3.0e-24	103	COG1923	sRNA-binding regulator protein Hfq	77
644379071	378	54.8	8	361	3	356	1.0e-121	430	COG2262	50S ribosomal subunit-associated GTPase HflX	411
644379072	404	31.48	49	349	1	289	1.0e-37	151	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
644379073	293	26.44	3	291	2	291	1.0e-41	164	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
644379074	383	38.3	3	381	2	387	6.0e-69	254	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
644379075	431	61.07	3	430	2	430	0.0e+00	649	COG0104	Adenylosuccinate synthase	430
644379076	146	38.51	10	146	2	149	3.0e-22	97.8	COG2165	Type II secretory pathway, pseudopilin PulG	149
644379077	396	37.78	1	396	2	397	1.0e-78	287	COG1459	Type II secretory pathway, component PulF	397
644379078	566	42.44	60	564	3	499	0.0e+00	497	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
644379083	659	27.62	8	658	10	598	8.0e-53	202	COG4796	Type II secretory pathway, component HofQ	709
644379084	169	27.85	14	169	7	149	4.0e-13	67.8	COG2165	Type II secretory pathway, pseudopilin PulG	149
644379086	203	22.05	22	147	7	130	5.0e-08	51.2	COG2165	Type II secretory pathway, pseudopilin PulG	149
644379089	240	21.16	1	235	4	241	1.0e-13	70.2	COG1651	Protein-disulfide isomerase	244
644379094	553	37.74	1	262	9	269	4.0e-47	182	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
644379098	741	47.52	31	723	2	706	0.0e+00	712	COG0557	Exoribonuclease R	706
644379108	192	33.17	1	192	3	204	1.0e-19	89.9	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644379109	274	33.64	169	274	17	123	5.0e-19	88.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644379111	370	35.53	3	370	71	436	4.0e-102	364	COG0621	tRNA A37 methylthiotransferase MiaB	437
644379113	188	35.96	5	174	9	185	7.0e-39	153	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
644379115	376	37.5	4	376	1	373	3.0e-65	242	COG2866	Murein tripeptide amidase MpaA	374
644379118	101	25.22	1	101	13	127	8.0e-07	45.4	COG2916	DNA-binding protein H-NS	128
644379119	325	31.21	25	321	16	292	2.0e-50	192	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
644379121	154	47.37	1	130	1	116	5.0e-32	130	COG1970	Large-conductance mechanosensitive channel	130
644379122	187	46.2	1	183	1	183	3.0e-37	148	COG2119	Putative Ca2+/H+ antiporter, TMEM165/GDT1 family	190
644379123	601	26.8	63	424	50	406	8.0e-47	182	COG0840	Methyl-accepting chemotaxis protein	408
644379127	117	28.26	17	108	1	91	7.0e-11	59.4	COG0789	DNA-binding transcriptional regulator, MerR family	124
644379128	98	46.81	2	95	1	94	3.0e-29	119	COG0776	Bacterial nucleoid DNA-binding protein	94
644379129	786	42.79	143	785	1	650	0.0e+00	642	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
644379130	327	56.29	1	325	3	335	3.0e-124	438	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
644379131	118	78.81	1	118	1	118	1.0e-39	154	COG0292	Ribosomal protein L20	118
644379132	65	52.31	1	65	1	65	5.0e-10	56	COG0291	Ribosomal protein L35	65
644379133	174	62.79	3	174	4	175	3.0e-63	234	COG0290	Translation initiation factor IF-3	176
644379134	632	57.76	34	630	1	580	0.0e+00	794	COG0441	Threonyl-tRNA synthetase	589
644379136	371	63.11	4	369	1	365	0.0e+00	549	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
644379137	106	49.48	10	106	1	97	1.0e-24	104	COG1862	Preprotein translocase subunit YajC	97
644379138	613	53.4	100	598	16	500	0.0e+00	484	COG0342	Preprotein translocase subunit SecD	506
644379139	311	46.28	1	308	1	305	4.0e-81	294	COG0341	Preprotein translocase subunit SecF	305
644379140	218	42.08	17	216	1	202	4.0e-38	151	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
644379141	629	45.09	1	628	1	638	0.0e+00	641	COG0323	DNA mismatch repair ATPase MutL	638
644379142	475	48.2	3	471	8	473	0.0e+00	584	COG2925	Exonuclease I	475
644379143	319	49.84	6	310	4	305	2.0e-101	362	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
644379144	138	39.62	1	98	1	106	6.0e-15	73.5	COG4968	Tfp pilus assembly protein PilE	139
644379145	172	29.94	1	167	1	177	2.0e-16	78.5	COG4970	Tfp pilus assembly protein FimT	181
644379146	157	23.31	3	153	1	161	2.0e-08	51.9	COG4967	Tfp pilus assembly protein PilV	162
644379150	116	31.93	1	113	8	126	5.0e-26	109	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
644379151	388	36.51	3	249	30	281	4.0e-72	265	COG1398	Fatty-acid desaturase	289
644379152	529	21.58	10	511	3	468	1.0e-36	148	COG5339	Uncharacterized conserved protein YdgA, DUF945 family	479
644379153	156	72.44	1	156	1	156	4.0e-56	210	COG2193	Bacterioferritin (cytochrome b1)	157
644379154	88	49.12	21	77	1	57	2.0e-13	67.3	COG2906	Bacterioferritin-associated ferredoxin	63
644379155	154	33.91	6	117	9	121	5.0e-10	57.3	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
644379157	358	58.38	3	357	2	352	0.0e+00	477	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
644379158	304	28.14	6	291	1	290	3.0e-30	126	COG0583	DNA-binding transcriptional regulator, LysR family	297
644379159	384	35.23	24	384	23	388	3.0e-84	305	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
644379160	271	38.89	7	269	3	263	2.0e-49	189	COG0388	Predicted amidohydrolase	274
644379161	257	30.83	1	248	2	261	7.0e-35	140	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644379163	947	68.58	1	939	3	935	0.0e+00	1566	COG0178	Excinuclease UvrABC ATPase subunit	935
644379164	452	22.4	24	386	30	387	8.0e-23	101	COG2814	Predicted arabinose efflux permease, MFS family	394
644379165	151	29.7	1	151	3	167	2.0e-22	98.2	COG0629	Single-stranded DNA-binding protein	167
644379168	683	19.52	1	609	1	595	4.0e-51	196	COG4688	Uncharacterized protein	665
644379170	701	29.32	47	687	39	679	1.0e-72	268	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
644379171	274	30.11	2	260	53	284	3.0e-33	135	COG4974	Site-specific recombinase XerD	300
644379180	257	20.93	10	254	7	256	2.0e-14	72.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
644379181	252	21.72	11	221	1	213	1.0e-12	66.9	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
644379183	417	40.1	1	416	2	412	8.0e-88	317	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644379184	164	27.7	10	152	2	142	4.0e-13	68	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
644379185	239	43.78	1	238	5	250	2.0e-41	162	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644379186	150	26.28	7	141	12	146	2.0e-21	95.1	COG4706	Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain	161
644379188	397	34.92	1	395	2	411	2.0e-75	276	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644379189	267	28.35	19	262	7	255	3.0e-26	112	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
644379191	783	30.71	8	780	17	786	1.0e-126	447	COG4258	Predicted exporter	788
644379195	448	22.04	9	439	34	519	8.0e-35	141	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
644379202	376	23.93	1	277	1	244	9.0e-45	174	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
644379203	591	48.95	16	537	7	511	0.0e+00	526	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
644379204	206	31.68	1	197	10	209	1.0e-26	113	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
644379205	231	36.82	12	231	5	206	5.0e-39	154	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
644379206	116	75.49	3	104	11	112	8.0e-35	138	COG5605	Cytochrome c oxidase subunit IV	115
644379207	330	41.74	3	328	1	333	2.0e-82	299	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644379208	833	40.85	4	145	1	142	1.0e-35	145	COG4668	Mannitol/fructose-specific phosphotransferase system, IIA domain	142
644379208	833	49.2	274	828	3	565	0.0e+00	620	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
644379209	318	47.6	5	317	2	310	3.0e-82	298	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
644379210	581	62.83	246	581	1	337	2.0e-104	373	COG1299	Phosphotransferase system, fructose-specific IIC component	343
644379211	313	39.87	6	312	13	320	3.0e-44	172	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
644379212	497	57.75	1	495	4	500	0.0e+00	626	COG1129	ABC-type sugar transport system, ATPase component	500
644379213	342	60	1	340	1	327	8.0e-89	320	COG4158	Predicted ABC-type sugar transport system, permease component	329
644379214	314	31.86	7	302	1	311	4.0e-31	129	COG0524	Sugar or nucleoside kinase, ribokinase family	311
644379215	268	33.98	1	257	2	257	5.0e-50	191	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
644379216	350	20.6	12	350	5	354	8.0e-20	91.6	COG3203	Outer membrane protein (porin)	354
644379217	567	53.14	44	535	2	445	0.0e+00	542	COG0166	Glucose-6-phosphate isomerase	446
644379218	166	49.69	4	166	5	167	3.0e-47	181	COG4702	Uncharacterized protein, UPF0303 family	168
644379219	353	36.08	3	344	2	338	1.0e-51	197	COG0673	Predicted dehydrogenase	342
644379220	542	29.5	32	507	3	460	3.0e-82	299	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644379221	476	48.73	6	472	1	474	0.0e+00	567	COG0469	Pyruvate kinase	477
644379222	217	26.79	23	184	13	179	7.0e-12	64.1	COG0740	ATP-dependent protease ClpP, protease subunit	200
644379223	453	36.59	1	437	1	410	3.0e-81	295	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
644379224	284	42.7	6	269	3	259	6.0e-51	194	COG2116	Formate/nitrite transporter FocA, FNT family	265
644379225	885	38	1	883	5	938	0.0e+00	820	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
644379228	391	27.75	3	343	18	328	1.0e-42	167	COG0205	6-phosphofructokinase	347
644379229	180	57.39	1	176	1	173	2.0e-57	215	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
644379230	294	57.79	4	292	1	286	2.0e-115	408	COG1209	dTDP-glucose pyrophosphorylase	286
644379231	297	48.46	1	293	1	281	1.0e-83	303	COG1091	dTDP-4-dehydrorhamnose reductase	281
644379232	353	59.42	2	345	3	334	0.0e+00	521	COG1088	dTDP-D-glucose 4,6-dehydratase	340
644379233	86	53.09	3	83	1	81	6.0e-22	95.5	COG4281	Acyl-CoA-binding protein	87
644379235	244	20.75	1	239	1	237	1.0e-19	90.3	COG1651	Protein-disulfide isomerase	244
644379236	388	36.67	7	388	2	385	2.0e-60	226	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
644379237	386	35.6	6	379	1	379	3.0e-50	192	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
644379238	431	31.55	19	425	11	384	3.0e-67	249	COG0006	Xaa-Pro aminopeptidase	384
644379240	241	57.85	1	241	1	241	5.0e-95	340	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
644379241	258	40	3	256	2	255	4.0e-39	154	COG1684	Flagellar biosynthesis protein FliR	258
644379242	89	52.81	1	89	1	89	3.0e-17	80.2	COG1987	Flagellar biosynthesis protein FliQ	89
644379244	248	57.26	1	246	1	248	1.0e-73	269	COG1338	Flagellar biosynthetic protein FliP	248
644379245	140	32	10	129	5	129	1.0e-15	76.1	COG3190	Flagellar biogenesis protein FliO	137
644379246	143	46.09	18	131	22	136	1.0e-22	98.9	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
644379247	335	46.35	4	316	3	316	8.0e-91	327	COG1868	Flagellar motor switch protein FliM	332
644379248	170	30.95	2	168	1	159	1.0e-23	103	COG1580	Flagellar basal body-associated protein FliL	159
644379250	148	31.91	7	147	8	148	3.0e-09	54.9	COG2882	Flagellar biosynthesis chaperone FliJ	148
644379251	464	56.06	29	464	25	440	0.0e+00	576	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
644379252	261	29.1	64	250	38	225	5.0e-18	85	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
644379253	332	47.22	4	325	12	335	8.0e-82	297	COG1536	Flagellar motor switch protein FliG	339
644379254	576	41.84	17	575	10	545	1.0e-121	430	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
644379255	105	41.9	1	105	2	105	1.0e-14	71.5	COG1677	Flagellar hook-basal body complex protein FliE	105
644379256	450	50.98	5	447	6	463	0.0e+00	467	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644379258	136	36.43	1	129	18	138	6.0e-25	106	COG0394	Protein-tyrosine-phosphatase	139
644379259	67	56.72	1	67	1	67	2.0e-24	104	COG1278	Cold shock protein, CspA family	67
644379260	670	67.07	7	664	2	658	0.0e+00	1099	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
644379261	290	32.88	1	286	1	283	1.0e-51	196	COG1686	D-alanyl-D-alanine carboxypeptidase	389
644379262	306	34.44	3	299	2	297	6.0e-36	144	COG0583	DNA-binding transcriptional regulator, LysR family	297
644379263	337	32.84	1	334	1	324	7.0e-61	227	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
644379264	212	35.24	1	209	1	208	4.0e-26	111	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644379265	348	42.94	1	346	2	351	7.0e-102	363	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644379266	536	33.82	1	531	1	530	4.0e-77	282	COG1178	ABC-type Fe3+ transport system, permease component	540
644379267	330	28.71	37	330	1	299	3.0e-43	169	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
644379268	366	31.94	104	317	12	215	7.0e-34	138	COG0543	NAD(P)H-flavin reductase	252
644379272	304	36.18	2	301	11	308	2.0e-50	192	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
644379275	102	55.06	1	89	1	83	2.0e-18	83.9	COG3813	Uncharacterized protein	84
644379276	183	26.9	1	142	1	171	5.0e-18	84.1	COG1335	Nicotinamidase-related amidase	205
644379277	203	34.34	4	193	7	204	9.0e-21	93.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644379278	481	36.61	7	480	1	458	1.0e-93	337	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644379280	386	57.37	7	386	20	399	2.0e-94	339	COG3135	Predicted benzoate:H+ symporter BenE	402
644379283	154	55.84	1	153	1	153	5.0e-49	186	COG2193	Bacterioferritin (cytochrome b1)	157
644379285	464	43.52	1	464	9	471	0.0e+00	485	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
644379286	209	28.78	1	198	4	208	1.0e-17	83.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644379287	477	35.52	3	471	2	455	5.0e-95	341	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644379289	516	34.48	10	435	9	432	3.0e-97	349	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
644379290	229	22.66	26	224	22	211	3.0e-08	52.4	COG3318	Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C motif	216
644379291	131	26.61	11	107	33	141	8.0e-07	46.2	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
644379294	287	56.45	1	287	1	287	4.0e-119	421	COG0788	Formyltetrahydrofolate hydrolase	287
644379295	283	63.41	4	279	1	276	2.0e-111	395	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
644379300	224	38.22	1	224	6	229	1.0e-34	140	COG1802	DNA-binding transcriptional regulator, GntR family	230
644379301	389	30.52	18	380	2	364	5.0e-41	162	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
644379303	207	55.96	7	199	5	197	7.0e-66	243	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
644379304	450	22.01	13	420	24	434	1.0e-26	114	COG2271	Sugar phosphate permease	448
644379305	168	53.12	9	168	1	160	2.0e-54	205	COG3265	Gluconate kinase	161
644379306	325	37.31	1	324	3	328	3.0e-74	272	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644379307	355	50.56	1	354	2	358	1.0e-113	403	COG0787	Alanine racemase	360
644379308	434	30.79	1	420	5	385	1.0e-50	194	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644379309	162	42.11	9	160	4	154	4.0e-35	140	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644379310	399	34.29	6	397	3	407	3.0e-77	282	COG0004	Ammonia channel protein AmtB	409
644379311	365	28.49	4	363	2	345	4.0e-24	105	COG3515	Predicted component of the type VI protein secretion system	346
644379312	87	48.81	4	87	14	97	2.0e-16	77.3	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
644379314	875	43.4	11	872	1	781	0.0e+00	775	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
644379315	338	38.01	15	331	14	326	5.0e-55	208	COG3520	Predicted component of the type VI protein secretion system	335
644379316	618	38.21	1	618	1	621	0.0e+00	498	COG3519	Type VI protein secretion system component VasA	621
644379322	899	36.09	12	615	4	539	8.0e-120	425	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
644379323	161	40.27	12	160	8	154	4.0e-18	84.2	COG3518	Predicted component of the type VI protein secretion system	157
644379324	234	29.56	34	233	51	253	1.0e-34	139	COG3455	Type VI protein secretion system component VasF	262
644379325	448	33.78	1	446	1	444	1.0e-84	307	COG3522	Predicted component of the type VI protein secretion system	446
644379326	178	34.4	22	140	13	134	2.0e-17	82.3	COG3521	Predicted component of the type VI protein secretion system	159
644379329	339	22.7	18	180	11	170	6.0e-07	48.6	COG3913	Uncharacterized protein	227
644379330	170	47.9	4	170	2	168	5.0e-48	183	COG3516	Predicted component of the type VI protein secretion system	169
644379331	494	58.1	1	494	2	495	0.0e+00	715	COG3517	Predicted component of the type VI protein secretion system	495
644379332	165	35.29	1	164	1	162	4.0e-33	134	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
644379333	162	22.76	6	146	19	160	6.0e-06	44.1	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
644379335	447	65.85	1	447	1	444	0.0e+00	640	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
644379336	178	71.59	3	178	1	176	7.0e-75	273	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
644379337	81	36.36	12	77	2	67	4.0e-09	53	COG2841	Uncharacterized conserved protein YdcH, DUF465 family	72
644379338	229	26.86	53	227	73	244	2.0e-12	65.9	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
644379339	225	36.28	6	220	1	215	1.0e-34	139	COG0811	Biopolymer transport protein ExbB/TolQ	216
644379340	136	40.44	1	136	1	135	3.0e-32	131	COG0848	Biopolymer transport protein ExbD	137
644379341	742	33.86	2	742	13	750	8.0e-125	441	COG4774	Outer membrane receptor for monomeric catechols	750
644379342	226	60.35	1	226	3	229	5.0e-85	307	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
644379344	478	26.9	99	371	69	355	4.0e-24	106	COG0840	Methyl-accepting chemotaxis protein	408
644379345	536	29.73	169	536	42	408	1.0e-41	164	COG0840	Methyl-accepting chemotaxis protein	408
644379348	448	49.56	5	447	3	456	0.0e+00	472	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644379349	516	25.79	196	506	5	319	6.0e-27	115	COG0642	Signal transduction histidine kinase	336
644379350	791	42.63	37	777	11	735	0.0e+00	721	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
644379351	155	49.03	3	155	1	154	7.0e-45	173	COG2153	Predicted N-acyltransferase, GNAT family	155
644379353	662	62.16	1	662	3	662	0.0e+00	1025	COG0021	Transketolase	663
644379354	337	60.53	2	337	1	333	0.0e+00	461	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
644379355	392	52.49	1	392	2	395	0.0e+00	465	COG0126	3-phosphoglycerate kinase	395
644379356	210	36.59	1	204	1	203	1.0e-28	119	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644379357	354	47.88	1	329	1	286	2.0e-98	352	COG0191	Fructose/tagatose bisphosphate aldolase	286
644379360	911	25.62	9	480	7	458	9.0e-51	195	COG0591	Na+/proline symporter	493
644379362	387	46.17	14	387	9	378	3.0e-85	309	COG3448	CBS-domain-containing membrane protein	382
644379364	83	41.67	2	83	1	84	6.0e-14	69.2	COG1977	Molybdopterin converting factor, small subunit	84
644379365	152	48	1	150	1	149	4.0e-42	163	COG0314	Molybdopterin synthase catalytic subunit	149
644379366	196	39.9	1	188	3	189	3.0e-33	134	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
644379367	264	43.1	4	241	4	226	5.0e-50	191	COG2013	Uncharacterized conserved protein, AIM24 family	227
644379368	358	68.09	1	350	1	351	0.0e+00	574	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
644379369	136	58.33	18	136	1	120	1.0e-24	105	COG1734	RNA polymerase-binding transcription factor DksA	120
644379370	101	48.51	1	101	6	106	1.0e-19	87.9	COG4654	Cytochrome c551/c552	110
644379372	267	45.66	1	262	2	265	1.0e-66	246	COG0345	Pyrroline-5-carboxylate reductase	266
644379373	231	57.21	3	229	1	228	1.0e-80	292	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
644379374	345	67.06	1	343	3	345	0.0e+00	534	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
644379375	378	63.47	4	378	1	374	0.0e+00	543	COG5008	Tfp pilus assembly protein, ATPase PilU	375
644379376	404	31.55	6	376	4	370	2.0e-58	220	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
644379377	168	32.96	1	168	1	177	1.0e-22	99.6	COG1514	2'-5' RNA ligase	180
644379378	247	62.96	3	245	1	240	8.0e-106	376	COG1126	ABC-type polar amino acid transport system, ATPase component	240
644379379	224	39.63	8	224	10	220	8.0e-46	177	COG0765	ABC-type amino acid transport system, permease component	222
644379380	247	37.56	21	241	14	222	3.0e-51	195	COG0765	ABC-type amino acid transport system, permease component	222
644379381	301	31.32	5	279	2	275	1.0e-40	160	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644379382	244	66.25	1	240	2	240	2.0e-111	395	COG1126	ABC-type polar amino acid transport system, ATPase component	240
644379383	258	51.79	6	254	4	254	2.0e-85	308	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
644379384	138	39.29	6	134	16	154	5.0e-14	70.3	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
644379385	105	36.79	1	104	1	106	1.0e-23	101	COG1965	Iron-binding protein CyaY, frataxin homolog	106
644379387	365	34.75	12	362	4	349	2.0e-53	203	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
644379389	515	41.99	341	513	1	181	5.0e-39	156	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644379390	1370	38.85	808	1368	229	864	2.0e-88	321	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
644379391	425	59.86	1	425	4	429	0.0e+00	597	COG0001	Glutamate-1-semialdehyde aminotransferase	432
644379392	156	59.09	1	153	1	154	9.0e-53	199	COG2954	CYTH domain, found in class IV adenylate cyclase and various triphosphatases	156
644379393	138	50	1	138	6	149	6.0e-33	133	COG1981	Uncharacterized membrane protein	149
644379394	126	31.82	9	112	5	113	1.0e-14	71.8	COG2315	Predicted DNA-binding protein with ?double-wing? structural motif, MmcQ/YjbR family	118
644379396	54	50.94	1	53	1	53	6.0e-13	65.7	COG1773	Rubredoxin	55
644379397	291	38.46	7	258	3	252	9.0e-62	230	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
644379398	205	43.75	1	205	2	208	2.0e-40	158	COG0352	Thiamine monophosphate synthase	211
644379399	420	47.12	3	414	1	416	1.0e-122	433	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
644379400	323	31.92	4	302	1	298	8.0e-56	211	COG0859	ADP-heptose:LPS heptosyltransferase	334
644379401	252	22.69	1	221	1	238	2.0e-12	66.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
644379402	325	33.33	1	323	1	312	5.0e-56	211	COG0451	Nucleoside-diphosphate-sugar epimerase	314
644379406	245	25.18	13	230	16	279	2.0e-12	66	COG0167	Dihydroorotate dehydrogenase	310
644379407	361	44.93	1	361	3	365	1.0e-97	349	COG1932	Phosphoserine aminotransferase	365
644379410	381	32.11	1	347	3	347	3.0e-48	186	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
644379411	215	48.1	8	214	1	210	2.0e-47	182	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644379412	405	50.36	109	386	10	283	1.0e-92	333	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
644379413	440	42.3	3	434	7	429	1.0e-108	386	COG1253	Hemolysin or related protein, contains CBS domains	429
644379414	240	52.7	12	232	1	222	5.0e-80	290	COG0692	Uracil DNA glycosylase	223
644379415	108	38.38	10	105	9	107	1.0e-17	81.5	COG0607	Rhodanese-related sulfurtransferase	110
644379416	219	37.44	6	200	1	195	1.0e-52	199	COG2518	Protein-L-isoaspartate O-methyltransferase	209
644379417	636	64.48	134	604	1	432	0.0e+00	752	COG0422	Thiamine biosynthesis protein ThiC	432
644379419	148	41.18	19	120	1	99	1.0e-08	53	COG1846	DNA-binding transcriptional regulator, MarR family	126
644379420	181	41.44	2	181	1	181	2.0e-34	138	COG3038	Cytochrome b561	181
644379423	407	52.97	3	403	2	396	4.0e-102	365	COG3214	Uncharacterized conserved protein YcaQ, contains winged helix DNA-binding domain	400
644379426	661	36.31	2	351	1	347	1.0e-73	271	COG0826	Collagenase-like protease, PrtC family	347
644379431	404	32.75	32	357	3	344	4.0e-62	232	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
644379432	692	32.72	311	692	32	408	1.0e-60	227	COG0840	Methyl-accepting chemotaxis protein	408
644379433	306	55.1	1	304	1	313	2.0e-113	402	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
644379434	152	55.63	1	150	3	152	6.0e-47	180	COG1781	Aspartate carbamoyltransferase, regulatory subunit	153
644379435	335	26.41	1	332	8	316	4.0e-23	102	COG0530	Ca2+/Na+ antiporter	320
644379436	170	47.62	1	167	2	169	2.0e-50	192	COG1247	L-amino acid N-acyltransferase YncA	169
644379441	719	36.38	12	612	4	539	4.0e-117	416	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
644379442	1160	33.04	17	699	2	634	0.0e+00	599	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
644379443	301	51.2	6	296	4	293	4.0e-70	258	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
644379444	263	32.95	1	252	1	252	1.0e-50	193	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
644379445	242	46.12	1	239	3	246	1.0e-61	229	COG1385	16S rRNA U1498 N3-methylase RsmE	246
644379446	770	51.74	581	751	1	171	1.0e-43	172	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644379448	445	28.34	30	434	1	423	2.0e-42	167	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
644379450	284	36.8	18	281	24	287	2.0e-56	212	COG0676	D-hexose-6-phosphate mutarotase	287
644379451	255	76.49	1	251	4	253	3.0e-117	414	COG4598	ABC-type histidine transport system, ATPase component	256
644379452	237	57.46	7	234	1	228	9.0e-77	280	COG4160	ABC-type arginine/histidine transport system, permease component	228
644379453	229	51.74	1	227	1	230	5.0e-71	260	COG4215	ABC-type arginine transport system, permease component	230
644379454	256	33.07	4	255	15	268	6.0e-40	157	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644379455	412	41.56	7	412	2	402	2.0e-93	336	COG1228	Imidazolonepropionase or related amidohydrolase	406
644379456	556	73.87	1	555	1	555	0.0e+00	976	COG2987	Urocanate hydratase	561
644379457	511	58.88	1	501	1	498	0.0e+00	631	COG2986	Histidine ammonia-lyase	498
644379458	350	36.34	18	350	1	331	2.0e-72	266	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644379459	567	37.14	258	563	1	305	1.0e-45	178	COG0524	Sugar or nucleoside kinase, ribokinase family	311
644379460	427	21.88	6	410	21	433	4.0e-28	119	COG2271	Sugar phosphate permease	448
644379461	335	49.39	4	324	1	324	9.0e-92	330	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
644379463	1032	18.6	92	934	5	661	4.0e-43	170	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
644379466	339	20.34	1	334	1	341	2.0e-16	80	COG3203	Outer membrane protein (porin)	354
644379467	379	51.25	1	359	1	338	2.0e-116	412	COG3839	ABC-type sugar transport system, ATPase component	338
644379468	542	40.12	12	506	1	494	6.0e-104	371	COG0366	Glycosidase	505
644379469	276	44.04	3	275	6	281	6.0e-56	211	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
644379470	314	38.8	18	314	1	294	9.0e-61	227	COG1175	ABC-type sugar transport system, permease component	295
644379471	422	25.58	1	413	7	429	8.0e-38	151	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
644379472	863	28.22	451	731	61	336	4.0e-33	137	COG0642	Signal transduction histidine kinase	336
644379473	242	47.66	5	237	1	227	2.0e-52	199	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644379474	370	35.54	1	367	1	374	3.0e-79	289	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
644379475	477	35.32	4	469	3	453	2.0e-88	319	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644379476	394	49.74	9	388	18	397	3.0e-76	279	COG3135	Predicted benzoate:H+ symporter BenE	402
644379477	325	24.25	6	298	1	297	1.0e-27	117	COG0583	DNA-binding transcriptional regulator, LysR family	297
644379478	534	31.31	123	534	4	408	1.0e-38	154	COG0840	Methyl-accepting chemotaxis protein	408
644379479	462	28.04	36	457	25	384	6.0e-49	188	COG0006	Xaa-Pro aminopeptidase	384
644379481	694	30.06	334	645	5	308	2.0e-30	128	COG0668	Small-conductance mechanosensitive channel	316
644379483	381	33.59	1	380	10	399	1.0e-62	234	COG4671	Predicted glycosyl transferase	400
644379484	392	43.81	1	388	7	390	6.0e-101	361	COG4671	Predicted glycosyl transferase	400
644379486	282	41.55	1	282	1	294	6.0e-58	217	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
644379489	217	39.22	1	198	1	194	2.0e-60	225	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
644379491	322	40.66	3	322	6	313	7.0e-84	304	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
644379493	224	28.34	10	194	7	188	5.0e-14	71.5	COG4583	Sarcosine oxidase gamma subunit	189
644379494	1005	36.62	611	1005	1	379	3.0e-104	373	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
644379495	98	53.49	1	86	1	85	5.0e-25	105	COG4311	Sarcosine oxidase delta subunit	97
644379496	417	27.41	30	407	1	387	1.0e-55	210	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644379497	287	54.36	1	287	1	287	1.0e-116	412	COG0788	Formyltetrahydrofolate hydrolase	287
644379499	726	81.29	1	726	12	730	0.0e+00	1276	COG0376	Catalase (peroxidase I)	730
644379500	324	24.75	4	300	1	297	5.0e-24	105	COG0583	DNA-binding transcriptional regulator, LysR family	297
644379501	308	38.19	1	306	1	293	2.0e-72	266	COG1131	ABC-type multidrug transport system, ATPase component	293
644379502	253	21.97	24	246	42	253	3.0e-08	52.5	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
644379504	296	46.82	1	296	1	282	2.0e-72	265	COG3833	ABC-type maltose transport system, permease component	282
644379505	507	37.84	250	507	52	295	3.0e-46	180	COG1175	ABC-type sugar transport system, permease component	295
644379506	402	35.41	12	402	14	413	6.0e-89	321	COG2182	Maltose-binding periplasmic protein MalE	420
644379507	378	55.49	1	355	1	338	6.0e-126	444	COG3839	ABC-type sugar transport system, ATPase component	338
644379508	534	37.55	11	504	1	498	5.0e-92	332	COG0366	Glycosidase	505
644379509	426	37.1	10	426	10	429	1.0e-70	261	COG4580	Maltoporin (phage lambda and maltose receptor)	429
644379510	337	36.98	1	336	1	333	5.0e-69	254	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644379513	532	35.54	57	498	1	495	4.0e-72	266	COG0366	Glycosidase	505
644379514	311	26.28	14	310	1	311	1.0e-30	127	COG0524	Sugar or nucleoside kinase, ribokinase family	311
644379515	487	46.65	7	480	2	470	0.0e+00	511	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644379516	580	50.09	1	539	4	539	0.0e+00	510	COG2303	Choline dehydrogenase or related flavoprotein	542
644379517	283	39.62	1	282	3	313	2.0e-69	255	COG0627	S-formylglutathione hydrolase FrmB	316
644379518	372	70.46	2	370	1	366	0.0e+00	573	COG1062	Zn-dependent alcohol dehydrogenase	366
644379519	295	34.59	10	293	9	296	4.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
644379520	261	18.9	5	248	8	258	5.0e-14	71.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644379522	532	27.65	116	519	1	350	1.0e-54	208	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
644379523	477	49.45	27	477	8	432	4.0e-123	435	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
644379524	147	34.31	14	147	2	137	7.0e-17	80	COG1371	SHS2 domain protein implicated in nucleic acid metabolism	137
644379525	331	31.47	2	278	39	319	7.0e-26	111	COG2843	Poly-gamma-glutamate biosynthesis protein CapA/YwtB (capsule formation), metallophosphatase superfamily	372
644379526	440	38.63	7	408	13	405	5.0e-89	321	COG1488	Nicotinic acid phosphoribosyltransferase	405
644379527	198	37.44	14	198	7	201	6.0e-31	127	COG1335	Nicotinamidase-related amidase	205
644379528	220	26.7	5	191	2	203	2.0e-10	59.6	COG0412	Dienelactone hydrolase	236
644379529	296	28.23	170	293	5	127	2.0e-17	83.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644379530	269	61.69	6	260	3	256	3.0e-102	365	COG4813	Trehalose utilization protein	261
644379531	368	32.57	18	362	1	340	7.0e-58	217	COG0673	Predicted dehydrogenase	342
644379532	649	29.21	246	649	10	408	5.0e-52	199	COG0840	Methyl-accepting chemotaxis protein	408
644379533	455	20.5	95	453	63	394	5.0e-12	66	COG2814	Predicted arabinose efflux permease, MFS family	394
644379534	289	58.74	4	289	2	286	9.0e-115	406	COG0788	Formyltetrahydrofolate hydrolase	287
644379535	149	29.17	12	128	3	121	1.0e-18	85.6	COG1539	Dihydroneopterin aldolase	121
644379536	197	32.28	7	195	5	187	1.0e-33	136	COG4583	Sarcosine oxidase gamma subunit	189
644379537	998	36.55	607	998	3	379	2.0e-108	387	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
644379538	96	55.29	1	85	1	85	5.0e-32	129	COG4311	Sarcosine oxidase delta subunit	97
644379539	414	28.24	29	404	1	387	3.0e-57	216	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644379540	458	51.42	173	454	1	262	4.0e-87	315	COG1760	L-serine deaminase	262
644379541	419	68.95	8	416	7	412	0.0e+00	675	COG0112	Glycine/serine hydroxymethyltransferase	413
644379542	403	29.27	19	392	5	376	5.0e-49	188	COG0006	Xaa-Pro aminopeptidase	384
644379543	332	41.94	20	327	13	321	5.0e-78	284	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
644379544	211	34.74	5	194	1	174	1.0e-24	106	COG0431	NAD(P)H-dependent FMN reductase	184
644379545	302	41.46	3	288	1	286	6.0e-65	241	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
644379546	416	48.22	1	416	1	413	5.0e-95	341	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
644379547	224	36.55	8	202	8	192	7.0e-35	140	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
644379548	436	19.24	18	427	20	431	5.0e-22	99.5	COG2271	Sugar phosphate permease	448
644379549	262	62.69	1	260	1	260	1.0e-107	382	COG3622	Hydroxypyruvate isomerase	260
644379550	327	26.85	1	320	1	308	4.0e-31	128	COG0451	Nucleoside-diphosphate-sugar epimerase	314
644379551	253	39.83	9	234	6	234	2.0e-37	149	COG2186	DNA-binding transcriptional regulator, FadR family	241
644379553	375	49.6	1	372	8	386	7.0e-124	437	COG3146	Predicted N-acyltransferase	387
644379554	530	41.01	254	522	5	268	1.0e-69	257	COG0171	NH3-dependent NAD+ synthetase	268
644379555	201	40.2	1	200	6	209	3.0e-37	148	COG2834	Outer membrane lipoprotein-sorting protein	211
644379556	439	57.89	3	435	4	436	0.0e+00	571	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
644379558	428	58.43	1	427	1	426	0.0e+00	586	COG0172	Seryl-tRNA synthetase	429
644379575	544	36.21	5	540	3	486	7.0e-89	321	COG0286	Type I restriction-modification system, DNA methylase subunit	489
644379577	421	18.52	77	413	42	388	1.0e-19	91.6	COG0732	Restriction endonuclease S subunit	391
644379580	989	26.98	5	957	8	941	1.0e-122	434	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
644379581	310	49.02	10	264	1	247	2.0e-69	256	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
644379582	681	53.83	39	609	1	566	0.0e+00	618	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
644379583	204	46.39	12	204	18	209	9.0e-43	166	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
644379584	107	53.33	3	107	6	110	2.0e-21	94.1	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
644379585	308	43.75	1	288	16	301	3.0e-78	285	COG0109	Polyprenyltransferase (heme O synthase)	304
644379586	288	51.93	1	284	1	285	3.0e-79	288	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
644379587	110	50.62	9	88	6	86	2.0e-19	87.2	COG2257	Type III secretion system substrate exporter, FlhB-like	92
644379591	463	33.26	3	463	7	483	8.0e-45	175	COG1345	Flagellar capping protein FliD	483
644379592	140	27.45	39	140	20	120	6.0e-11	59.9	COG1334	Uncharacterized conserved protein, FlaG/YvyC family	120
644379594	1596	25.09	962	1225	1	254	6.0e-19	91	COG1216	Glycosyltransferase, GT2 family	305
644379595	388	40.16	1	379	1	372	3.0e-100	358	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
644379598	162	26.81	29	160	7	143	3.0e-08	51.4	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
644379599	370	22.53	33	343	16	318	1.0e-16	81.2	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
644379600	459	39.04	5	458	16	467	2.0e-92	333	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644379601	472	29.4	1	466	9	521	2.0e-65	243	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644379602	245	39.52	1	242	18	260	8.0e-54	203	COG0005	Purine nucleoside phosphorylase	262
644379603	180	37.72	15	180	9	175	9.0e-49	186	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
644379604	290	60	1	284	1	284	1.0e-119	422	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
644379605	488	27.8	2	199	56	260	1.0e-09	58.4	COG0457	Tetratricopeptide (TPR) repeat	291
644379606	815	51.42	8	642	1	589	0.0e+00	748	COG0272	NAD-dependent DNA ligase	667
644379607	388	18.03	140	365	90	317	9.0e-08	51.6	COG3115	Cell division protein ZipA, interacts with FtsZ	324
644379608	155	35.45	21	130	5	114	3.0e-17	81.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
644379609	181	45.14	1	174	2	176	9.0e-34	136	COG3038	Cytochrome b561	181
644379610	182	29.47	2	178	3	192	8.0e-27	113	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
644379611	190	46.35	1	190	1	192	6.0e-41	160	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
644379612	1161	32.15	1	1158	1	1163	0.0e+00	569	COG1196	Chromosome segregation ATPase	1163
644379613	186	53.19	1	186	8	194	8.0e-59	219	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
644379614	142	43.57	4	142	2	141	4.0e-36	143	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
644379616	311	37.82	1	300	12	322	9.0e-67	247	COG1161	Ribosome biogenesis GTPase A	322
644379617	70	50	1	70	1	70	3.0e-21	93.1	COG3530	Uncharacterized conserved protein, DUF3820 family	71
644379618	112	40.19	5	111	13	118	5.0e-21	92.6	COG3671	Uncharacterized membrane protein	125
644379620	539	32.97	1	452	2	396	2.0e-79	290	COG0644	Dehydrogenase (flavoprotein)	396
644379621	397	51.64	1	397	4	396	0.0e+00	468	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
644379622	395	38.4	22	394	5	392	2.0e-77	282	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644379623	258	37.45	13	254	1	241	9.0e-43	167	COG1414	DNA-binding transcriptional regulator, IclR family	246
644379624	398	29.87	4	391	2	350	1.0e-53	204	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
644379626	291	55.6	24	289	2	264	1.0e-85	309	COG0548	Acetylglutamate kinase	265
644379627	219	28.24	11	180	8	177	4.0e-15	75.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644379628	357	30.6	1	354	4	367	2.0e-23	103	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644379629	1043	30.31	6	1012	1	1008	0.0e+00	822	COG0841	Multidrug efflux pump subunit AcrB	1009
644379630	471	30.02	34	468	14	456	9.0e-43	168	COG1538	Outer membrane protein TolC	457
644379631	421	53.13	1	421	16	445	0.0e+00	502	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
644379632	486	50.64	12	481	1	467	0.0e+00	538	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644379634	212	52.17	1	207	1	206	1.0e-63	236	COG2808	Predicted FMN-binding regulatory protein PaiB	209
644379635	198	25.42	15	186	11	186	8.0e-16	77.3	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644379636	135	36.04	12	120	1	110	8.0e-12	63	COG0607	Rhodanese-related sulfurtransferase	110
644379637	490	38.77	20	486	3	458	5.0e-105	375	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644379639	103	73.79	1	103	1	103	3.0e-38	149	COG0051	Ribosomal protein S10	104
644379640	214	57.01	2	214	1	214	2.0e-73	268	COG0087	Ribosomal protein L3	218
644379641	206	40.95	1	206	2	211	9.0e-56	210	COG0088	Ribosomal protein L4	214
644379642	100	58.51	6	98	1	94	5.0e-23	99.5	COG0089	Ribosomal protein L23	94
644379644	92	66.3	1	92	1	92	3.0e-36	143	COG0185	Ribosomal protein S19	93
644379645	109	61.11	1	108	9	116	5.0e-33	132	COG0091	Ribosomal protein L22	120
644379646	233	59.09	12	230	1	220	1.0e-77	282	COG0092	Ribosomal protein S3	233
644379647	138	61.31	1	135	2	138	3.0e-46	177	COG0197	Ribosomal protein L16/L10AE	146
644379649	87	67.09	8	86	9	87	7.0e-22	95.7	COG0186	Ribosomal protein S17	87
644379650	122	74.59	1	122	1	122	1.0e-49	188	COG0093	Ribosomal protein L14	122
644379651	104	57.69	1	103	2	104	3.0e-19	86.9	COG0198	Ribosomal protein L24	104
644379652	179	68.16	1	179	1	179	2.0e-75	275	COG0094	Ribosomal protein L5	180
644379653	101	65.57	41	101	1	61	6.0e-18	82.2	COG0199	Ribosomal protein S14	61
644379654	131	61.83	1	130	1	131	2.0e-45	174	COG0096	Ribosomal protein S8	132
644379655	177	53.11	1	176	1	176	5.0e-57	213	COG0097	Ribosomal protein L6P/L9E	178
644379656	117	50.83	1	117	6	125	9.0e-27	112	COG0256	Ribosomal protein L18	125
644379657	172	54.27	7	169	18	181	3.0e-51	194	COG0098	Ribosomal protein S5	181
644379658	61	51.92	7	58	1	52	4.0e-12	62.8	COG1841	Ribosomal protein L30/L7E	55
644379659	144	47.33	1	144	1	150	3.0e-29	121	COG0200	Ribosomal protein L15	152
644379660	439	51.89	12	428	15	432	2.0e-124	439	COG0201	Preprotein translocase subunit SecY	436
644379661	72	66.67	1	72	1	72	2.0e-26	110	COG0361	Translation initiation factor IF-1	75
644379662	120	61.16	1	120	1	121	1.0e-40	157	COG0099	Ribosomal protein S13	121
644379663	131	65.62	4	131	2	129	1.0e-46	178	COG0100	Ribosomal protein S11	129
644379664	206	60.1	1	206	1	205	9.0e-62	229	COG0522	Ribosomal protein S4 or related protein	205
644379665	327	53.33	8	321	1	313	1.0e-98	353	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
644379666	130	71.55	1	116	1	116	7.0e-44	169	COG0203	Ribosomal protein L17	116
644379667	304	55.88	1	304	4	309	1.0e-113	403	COG2066	Glutaminase	309
644379668	265	40.75	1	262	2	265	7.0e-63	234	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
644379669	547	33.33	179	546	42	407	5.0e-49	189	COG0840	Methyl-accepting chemotaxis protein	408
644379670	497	37.45	2	496	13	517	5.0e-91	328	COG0815	Apolipoprotein N-acyltransferase	518
644379671	283	50.53	2	280	9	288	2.0e-91	329	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
644379672	168	47.14	28	166	14	153	2.0e-40	158	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
644379673	323	54.35	1	310	11	332	2.0e-106	378	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
644379674	98	32.61	1	92	3	91	1.0e-12	64.5	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
644379675	444	51.47	1	439	2	436	0.0e+00	550	COG0621	tRNA A37 methylthiotransferase MiaB	437
644379678	336	36.67	217	336	8	125	6.0e-16	78.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644379679	343	31.48	111	325	12	215	2.0e-37	149	COG0543	NAD(P)H-flavin reductase	252
644379680	162	47.53	1	162	3	164	5.0e-45	173	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
644379681	462	25.12	28	455	4	362	1.0e-51	197	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
644379682	368	29.52	1	368	2	368	6.0e-61	228	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644379683	96	45.56	1	90	1	90	4.0e-29	119	COG4829	Muconolactone delta-isomerase	98
644379684	306	27.13	52	291	2	219	2.0e-29	123	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
644379685	528	27.64	175	525	60	407	1.0e-36	148	COG0840	Methyl-accepting chemotaxis protein	408
644379686	274	34.98	33	273	3	244	2.0e-44	172	COG1414	DNA-binding transcriptional regulator, IclR family	246
644379687	631	46.99	463	626	16	180	7.0e-39	156	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644379689	439	18.64	1	412	1	365	9.0e-18	85.1	COG1106	ATPase/GTPase, AAA15 family	371
644379691	356	25.08	1	283	1	282	1.0e-31	130	COG4128	Zona occludens toxin, predicted ATPase	398
644379702	330	26.2	76	320	27	291	3.0e-22	99.9	COG4974	Site-specific recombinase XerD	300
644379705	383	42.86	22	375	7	368	8.0e-88	317	COG1565	SAM-dependent methyltransferase, MidA family	370
644379706	247	37.3	1	244	2	251	1.0e-35	143	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644379707	320	32.23	20	314	1	294	7.0e-53	201	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
644379708	266	26.85	4	240	1	257	1.0e-37	149	COG0421	Spermidine synthase	282
644379709	371	25.43	29	369	2	342	1.0e-44	174	COG0673	Predicted dehydrogenase	342
644379712	365	44.77	3	364	1	371	2.0e-110	392	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
644379713	429	22.13	14	384	8	377	8.0e-11	62	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
644379714	176	28.48	21	175	13	145	2.0e-12	65.6	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
644379715	405	27.97	28	402	37	373	3.0e-36	146	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
644379716	354	21.24	6	354	14	381	1.0e-15	78.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644379717	369	25.63	25	367	30	380	5.0e-26	112	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644379719	408	24.74	31	405	17	372	2.0e-21	97	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644379720	352	23.92	7	349	14	365	2.0e-07	50.2	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
644379721	214	30.54	1	214	1	237	3.0e-34	138	COG2872	Ser-tRNA(Ala) deacylase AlaX (editing enzyme)	241
644379722	387	46.07	5	386	4	372	1.0e-120	426	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
644379723	212	44.12	11	212	34	222	4.0e-51	194	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
644379724	634	44.94	16	615	1	581	0.0e+00	621	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
644379725	202	43.82	107	195	6	93	5.0e-19	87.6	COG3326	Uncharacterized membrane protein YsdA, DUF1294 family	94
644379726	403	37.95	220	382	16	181	1.0e-34	141	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644379727	350	39.94	1	350	1	316	5.0e-83	301	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
644379728	122	33.33	11	120	8	115	5.0e-12	63.4	COG3171	Uncharacterized conserved protein YggL, DUF469 family	119
644379729	491	57.23	1	491	1	475	0.0e+00	666	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
644379730	200	41.04	1	200	3	213	3.0e-48	185	COG3047	Outer membrane protein W	213
644379731	351	25.96	12	319	2	298	7.0e-73	267	COG0031	Cysteine synthase	300
644379733	183	25.7	11	180	48	225	8.0e-19	86.9	COG1011	FMN phosphatase YigB, HAD superfamily	229
644379736	327	40.89	6	317	8	320	5.0e-85	307	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
644379737	271	74.6	16	267	3	253	9.0e-118	416	COG4598	ABC-type histidine transport system, ATPase component	256
644379738	243	57.94	28	240	15	228	1.0e-69	256	COG4160	ABC-type arginine/histidine transport system, permease component	228
644379739	229	49.13	1	227	1	230	1.0e-66	246	COG4215	ABC-type arginine transport system, permease component	230
644379740	254	35.66	4	254	16	270	1.0e-37	150	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644379741	254	34.24	4	253	16	269	7.0e-40	157	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644379742	1603	47.32	17	1597	19	1585	0.0e+00	1592	COG2902	NAD-specific glutamate dehydrogenase	1592
644379743	370	47.62	12	367	5	352	1.0e-116	413	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
644379744	345	29.36	8	343	15	363	1.0e-51	197	COG0687	Spermidine/putrescine-binding periplasmic protein	363
644379745	420	47.93	194	410	60	276	2.0e-65	243	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
644379746	274	43.92	14	268	10	264	4.0e-55	208	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
644379747	150	51.03	8	150	6	148	4.0e-47	180	COG0756	dUTPase	148
644379748	393	49.11	1	390	2	391	2.0e-109	389	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
644379749	224	50.89	1	224	1	224	1.0e-69	255	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
644379751	299	41.29	3	296	1	310	7.0e-48	184	COG0524	Sugar or nucleoside kinase, ribokinase family	311
644379752	463	37.04	167	461	42	330	5.0e-44	172	COG0642	Signal transduction histidine kinase	336
644379753	228	48.89	10	227	3	226	2.0e-59	222	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644379755	339	29.45	7	324	4	303	4.0e-31	129	COG3547	Transposase	303
644379760	202	27.37	28	201	13	183	1.0e-13	69.8	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
644379761	601	37.09	4	596	8	607	1.0e-126	447	COG2905	Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains	610
644379762	264	51.79	1	250	1	244	4.0e-78	284	COG0121	Predicted glutamine amidotransferase	252
644379763	195	24.87	1	187	4	176	1.0e-25	109	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
644379764	293	41.52	1	279	1	286	2.0e-78	286	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
644379766	208	62.96	17	205	6	193	2.0e-71	261	COG0807	GTP cyclohydrolase II	193
644379771	210	48.58	1	210	2	213	4.0e-54	204	COG1926	Predicted phosphoribosyltransferase	220
644379772	2093	39.79	299	1163	2	849	0.0e+00	594	COG3899	Predicted ATPase	849
644379775	270	36.98	4	266	19	282	5.0e-44	171	COG1562	Phytoene/squalene synthetase	288
644379776	281	45.2	1	278	7	286	9.0e-64	237	COG1562	Phytoene/squalene synthetase	288
644379777	429	26.77	2	412	7	432	2.0e-39	157	COG2907	Predicted NAD/FAD-binding protein	447
644379778	253	27.98	8	200	1	189	2.0e-29	123	COG0300	Short-chain dehydrogenase	265
644379780	453	61.4	1	452	1	454	0.0e+00	643	COG1066	Predicted ATP-dependent serine protease	456
644379781	186	32.96	5	183	19	182	2.0e-22	98.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644379783	115	27.03	1	111	1	103	5.0e-15	73.1	COG4378	Uncharacterized protein	103
644379785	560	37.48	9	528	4	517	1.0e-114	407	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
644379786	290	37.13	8	170	38	197	6.0e-30	124	COG0791	Cell wall-associated hydrolase, NlpC family	197
644379788	415	48.44	1	415	1	408	1.0e-110	393	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
644379789	235	49.78	4	225	1	223	2.0e-76	278	COG1136	ABC-type lipoprotein export system, ATPase component	226
644379791	208	47.87	8	195	9	196	3.0e-47	181	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
644379792	147	22.22	1	132	7	138	1.0e-08	52.7	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
644379794	249	36.25	4	246	10	255	3.0e-35	142	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
644379795	245	60.82	1	245	1	245	3.0e-98	351	COG1135	ABC-type methionine transport system, ATPase component	339
644379796	228	54.42	14	228	8	222	5.0e-67	247	COG2011	ABC-type methionine transport system, permease component	222
644379797	269	46.27	2	266	1	267	4.0e-75	274	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
644379802	426	26.6	20	408	4	375	2.0e-31	130	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644379803	456	59.07	1	454	2	463	0.0e+00	546	COG1282	NAD/NADP transhydrogenase beta subunit	463
644379805	387	56.56	2	366	1	356	4.0e-105	375	COG3288	NAD/NADP transhydrogenase alpha subunit	356
644379806	251	27.67	1	251	5	256	2.0e-10	59.6	COG0730	Uncharacterized membrane protein YfcA	258
644379807	248	36.95	6	244	5	253	7.0e-42	164	COG0584	Glycerophosphoryl diester phosphodiesterase	257
644379808	499	44.95	5	495	13	513	0.0e+00	474	COG0578	Glycerol-3-phosphate dehydrogenase	532
644379809	876	45.45	675	838	1	162	9.0e-29	122	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644379810	450	52.12	9	450	6	454	0.0e+00	555	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
644379811	550	43.65	249	547	6	304	2.0e-72	266	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
644379812	69	65.22	1	69	6	74	2.0e-23	100	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
644379814	466	47.25	8	462	1	408	1.0e-128	453	COG0593	Chromosomal replication initiation ATPase DnaA	408
644379815	368	41.87	7	368	6	364	7.0e-83	301	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
644379816	796	61.48	1	563	1	563	0.0e+00	887	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
644379822	555	42.57	1	536	3	523	0.0e+00	524	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644379824	409	29.29	5	284	4	253	1.0e-35	144	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
644379827	527	24.81	2	395	21	351	2.0e-38	153	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
644379830	270	50.88	9	233	4	229	1.0e-70	260	COG1131	ABC-type multidrug transport system, ATPase component	293
644379831	462	42.3	5	462	1	460	1.0e-118	420	COG1113	L-asparagine transporter and related permeases	462
644379832	416	64.36	3	404	6	405	0.0e+00	539	COG3844	Kynureninase	407
644379833	211	34.86	1	210	5	217	3.0e-39	155	COG1878	Kynurenine formamidase	218
644379834	157	44.9	1	147	4	149	3.0e-33	134	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644379836	158	25	1	154	1	155	2.0e-26	111	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
644379837	68	50.82	10	67	1	61	3.0e-15	73.5	COG3369	Uncharacterized protein, contains Zn-finger domain of CDGSH type	78
644379838	213	55.35	1	213	1	214	3.0e-75	274	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
644379839	417	50	1	416	1	414	1.0e-126	446	COG0373	Glutamyl-tRNA reductase	414
644379840	358	65.19	1	358	1	362	0.0e+00	543	COG0216	Protein chain release factor A	363
644379843	288	22.99	29	287	36	285	1.0e-05	44.1	COG5006	Threonine/homoserine efflux transporter RhtA	292
644379844	313	39.87	1	300	3	302	2.0e-77	282	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
644379845	296	55.52	1	295	1	298	1.0e-100	359	COG3246	Uncharacterized conserved protein, DUF849 family	298
644379846	321	39.51	5	286	1	279	4.0e-62	232	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
644379847	165	25.36	1	138	2	137	1.0e-17	82.6	COG0824	Acyl-CoA thioesterase FadM	137
644379848	652	38.99	81	626	1	522	2.0e-130	459	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
644379849	330	49.06	5	322	2	321	7.0e-86	311	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
644379850	425	33.94	18	396	5	372	3.0e-30	126	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644379851	1030	38.61	2	1015	1	1009	0.0e+00	924	COG0841	Multidrug efflux pump subunit AcrB	1009
644379852	1034	39.67	4	1014	3	1009	0.0e+00	912	COG0841	Multidrug efflux pump subunit AcrB	1009
644379858	214	41.23	3	210	1	201	9.0e-49	186	COG0461	Orotate phosphoribosyltransferase	201
644379859	258	41.44	2	255	1	260	2.0e-76	279	COG0708	Exonuclease III	261
644379860	198	39.58	5	196	1	176	3.0e-41	161	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
644379861	279	43.84	5	278	12	281	6.0e-66	244	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
644379862	134	30	1	131	1	138	1.0e-18	85.8	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
644379863	537	33.15	170	537	45	408	2.0e-39	157	COG0840	Methyl-accepting chemotaxis protein	408
644379864	120	35.59	1	115	1	117	7.0e-20	89.2	COG3232	5-carboxymethyl-2-hydroxymuconate isomerase	127
644379865	1283	24.21	870	1263	3	388	5.0e-44	173	COG0247	Fe-S oxidoreductase	388
644379866	332	58.97	5	328	4	332	5.0e-108	384	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
644379867	428	17.92	3	280	1	269	1.0e-13	71.3	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
644379868	737	30.08	1	733	15	776	7.0e-115	408	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
644379869	346	45.88	1	328	12	347	5.0e-87	314	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
644379871	176	58.97	6	161	1	156	1.0e-48	185	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
644379872	197	51.24	1	195	1	201	8.0e-56	210	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
644379873	248	40.55	1	248	4	250	6.0e-39	154	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644379875	210	55.5	11	210	5	203	9.0e-68	249	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
644379876	344	70.21	15	343	3	330	0.0e+00	537	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
644379877	238	36.7	21	206	15	197	7.0e-35	140	COG0518	GMP synthase - Glutamine amidotransferase domain	198
644379879	372	52.47	10	372	8	369	3.0e-126	445	COG0263	Glutamate 5-kinase	369
644379881	449	45.17	3	434	2	444	0.0e+00	505	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
644379884	593	17.8	48	401	47	383	7.0e-07	49.4	COG3307	O-antigen ligase	424
644379885	287	40.43	7	283	60	335	5.0e-67	247	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
644379886	302	35.57	4	301	2	296	1.0e-52	200	COG2177	Cell division protein FtsX	297
644379887	217	51.64	1	213	1	213	2.0e-80	292	COG2884	ABC-type ATPase involved in cell division	223
644379888	358	53.94	51	358	24	340	8.0e-106	377	COG0552	Signal recognition particle GTPase	340
644379889	470	30.07	43	455	21	435	8.0e-77	281	COG0612	Predicted Zn-dependent peptidase	438
644379890	439	29.98	28	437	17	430	2.0e-65	243	COG0612	Predicted Zn-dependent peptidase	438
644379891	186	45.16	7	180	1	186	2.0e-45	175	COG0742	16S rRNA G966 N2-methylase RsmD	187
644379896	396	84.6	1	396	1	394	0.0e+00	719	COG0050	Translation elongation factor EF-Tu, a GTPase	394
644379898	117	38.03	39	109	1	71	1.0e-09	55.4	COG0690	Preprotein translocase subunit SecE	73
644379899	177	57.63	1	177	1	177	2.0e-53	202	COG0250	Transcription antitermination factor NusG	178
644379900	143	71.13	2	143	1	141	5.0e-53	200	COG0080	Ribosomal protein L11	141
644379901	231	61.4	1	227	1	228	2.0e-80	292	COG0081	Ribosomal protein L1	228
644379903	165	47.24	1	161	1	163	1.0e-32	132	COG0244	Ribosomal protein L10	175
644379904	123	69.35	1	123	1	124	1.0e-25	108	COG0222	Ribosomal protein L7/L12	124
644379906	1397	49.94	20	853	7	808	0.0e+00	889	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
644379907	123	78.05	1	123	7	129	3.0e-50	190	COG0048	Ribosomal protein S12	129
644379908	156	62.84	2	149	1	148	2.0e-54	204	COG0049	Ribosomal protein S7	148
644379909	699	66.38	1	699	1	692	0.0e+00	1007	COG0480	Translation elongation factor EF-G, a GTPase	697
644379910	405	47.92	2	405	1	404	0.0e+00	477	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
644379911	628	50.75	29	622	2	586	0.0e+00	699	COG0514	Superfamily II DNA helicase RecQ	590
644379913	259	34.48	3	259	2	253	4.0e-43	168	COG1192	Cellulose biosynthesis protein BcsQ	259
644379914	864	36.19	597	852	94	336	5.0e-39	156	COG0642	Signal transduction histidine kinase	336
644379916	762	35.41	495	744	38	293	9.0e-61	228	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
644379918	131	27.82	1	131	3	133	3.0e-20	90.7	COG0824	Acyl-CoA thioesterase FadM	137
644379920	330	26.76	14	311	1	296	3.0e-23	102	COG0583	DNA-binding transcriptional regulator, LysR family	297
644379921	67	40.91	3	67	7	72	9.0e-10	55.3	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
644379922	374	32.45	10	374	31	393	2.0e-74	272	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
644379923	273	53.82	5	272	5	270	5.0e-83	301	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
644379924	273	57.31	1	259	2	261	3.0e-101	361	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
644379925	261	50.38	2	261	5	263	8.0e-64	237	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
644379927	205	33.33	1	196	3	202	4.0e-36	144	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
644379928	100	40.48	10	93	14	97	1.0e-11	61.8	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
644379929	250	39.67	2	234	5	241	4.0e-58	218	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
644379930	215	30.2	1	202	2	200	5.0e-10	58.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644379931	300	40.2	1	297	1	293	3.0e-73	268	COG1131	ABC-type multidrug transport system, ATPase component	293
644379932	251	23.39	25	242	45	252	6.0e-10	58.2	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
644379933	82	45.45	3	79	2	77	6.0e-19	85.7	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
644379934	417	63.01	1	417	1	419	0.0e+00	614	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
644379941	156	47.13	1	155	21	173	7.0e-45	173	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
644379942	339	24.12	1	335	2	339	3.0e-12	66.5	COG0628	Predicted PurR-regulated permease PerM	355
644379943	1147	45.98	3	1136	1	1131	0.0e+00	1249	COG0587	DNA polymerase III, alpha subunit	1139
644379945	760	57.47	1	433	13	432	0.0e+00	588	COG0281	Malic enzyme	432
644379946	427	46.97	47	425	1	379	8.0e-97	347	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
644379947	204	33.73	1	167	8	162	2.0e-22	98.9	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
644379948	334	42.81	1	325	2	327	4.0e-88	318	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
644379950	524	56.3	5	524	9	512	0.0e+00	679	COG0029	Aspartate oxidase	518
644379953	453	44.51	20	190	7	179	7.0e-35	142	COG2059	Chromate transport protein ChrA	195
644379954	325	25.68	36	316	37	331	2.0e-17	83.7	COG3391	DNA-binding beta-propeller fold protein YncE	381
644379955	124	46.22	8	124	23	138	7.0e-26	109	COG4315	Predicted lipoprotein with conserved Yx(FWY)xxD motif (function unknown)	138
644379956	308	42.4	59	308	12	257	3.0e-58	219	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
644379957	270	56.32	1	261	1	257	7.0e-103	366	COG4525	ABC-type taurine transport system, ATPase component	259
644379958	342	47.31	8	340	5	334	6.0e-97	347	COG4521	ABC-type taurine transport system, periplasmic component	334
644379959	478	24.31	62	448	2	385	4.0e-44	172	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644379960	132	25.44	8	120	7	120	2.0e-07	48	COG3631	Ketosteroid isomerase-related protein	133
644379961	502	37.53	20	498	1	458	1.0e-100	360	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644379962	213	38.83	10	212	1	205	1.0e-42	166	COG0352	Thiamine monophosphate synthase	211
644379963	265	61.78	1	259	4	259	2.0e-98	352	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
644379964	67	47.69	3	67	4	68	3.0e-13	66.8	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
644379967	345	35.52	13	341	3	334	3.0e-53	202	COG2855	Uncharacterized membrane protein YadS	334
644379968	475	45.4	1	464	1	460	2.0e-121	429	COG1113	L-asparagine transporter and related permeases	462
644379969	487	33.48	3	467	105	537	1.0e-90	327	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
