gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
2904404937	305	49.82	51	303	42	180	1.2e-10	36.2	COG0500	SAM-dependent methyltransferase	257
2904404941	464	94.38	5	438	15	400	1.6e-34	114.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904404944	416	98.78	1	415	3	407	6.4e-48	157.3	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2904404945	246	97.79	9	234	2	222	2.2e-85	279.7	COG1136	ABC-type lipoprotein export system, ATPase component	226
2904404946	623	37.8	508	580	21	68	1.4e-07	7.3	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
2904404946	623	77.17	403	511	25	122	1.4e-07	16.2	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
2904404947	406	78.65	40	406	71	350	5.9e-48	157.8	COG3424	Predicted naringenin-chalcone synthase	356
2904404948	2522	27.99	2033	2201	124	198	3.1e-19	4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904404948	2522	77.99	2213	2516	4	212	3.1e-19	64	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904404948	2522	79.42	309	672	6	279	6.0e-42	84.9	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2904404948	2522	89.05	679	1797	5	1061	0.0e+00	842.3	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2904404948	2522	91.01	12	305	27	340	6.0e-42	51.8	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2904404950	421	64.49	55	363	125	351	8.2e-74	243.2	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2904404952	337	99.43	3	337	2	350	1.3e-75	249.2	COG0673	Predicted dehydrogenase	342
2904404953	349	97.37	4	341	7	302	1.5e-42	140.4	COG0176	Transaldolase	239
2904404954	168	100	1	168	1	166	8.6e-63	204.9	COG0678	Peroxiredoxin	165
2904404955	276	98.46	8	270	4	258	1.6e-78	257.8	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2904404956	142	95.36	1	142	1	144	3.2e-49	160.8	COG0698	Ribose 5-phosphate isomerase RpiB	151
2904404957	207	96.21	1	207	6	208	3.0e-76	249.7	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
2904404958	606	98.62	4	605	5	574	0.0e+00	655.6	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2904404959	491	98.77	4	490	6	485	0.0e+00	626.6	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
2904404960	235	94.17	2	235	5	230	2.3e-53	175.4	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
2904404962	150	86.25	73	147	2	70	1.3e-12	41.6	COG0695	Glutaredoxin	80
2904404964	216	98.05	3	211	3	203	3.8e-59	193.7	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
2904404965	425	98.83	1	425	1	424	0.0e+00	603.1	COG0151	Phosphoribosylamine-glycine ligase	428
2904404967	334	96.67	7	334	11	329	2.8e-97	319.9	COG0714	MoxR-like ATPase	329
2904404968	213	97.04	3	210	3	199	2.5e-63	207.7	COG0461	Orotate phosphoribosyltransferase	201
2904404970	305	98.87	30	304	2	263	2.4e-107	352.2	COG0548	Acetylglutamate kinase	265
2904404971	151	99.33	1	151	1	148	4.3e-60	195.9	COG0756	dUTPase	148
2904404972	406	99.5	3	397	2	400	0.0e+00	437.3	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
2904404973	224	99.55	1	224	2	224	1.0e-91	300.6	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
2904404974	227	62.76	33	211	54	203	4.3e-18	58.8	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2904404975	420	91.6	3	383	7	333	9.0e-55	180	COG0205	6-phosphofructokinase	347
2904404976	710	98.44	42	710	8	699	0.0e+00	952.1	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
2904404977	366	97.92	1	361	4	380	6.0e-108	355.2	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
2904404978	469	88.58	194	463	13	268	6.1e-35	114.3	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
2904404979	454	88.93	178	447	10	266	8.7e-37	119.3	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
2904404980	681	98.83	1	679	8	682	0.0e+00	944.5	COG0339	Zn-dependent oligopeptidase	683
2904404981	503	83.18	1	501	45	499	5.3e-31	102.3	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
2904404982	215	94.04	2	215	14	218	2.0e-36	119.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2904404983	139	97.81	1	137	2	135	1.3e-44	145.7	COG1765	Uncharacterized OsmC-related protein	137
2904404984	264	99.27	3	182	2	137	5.5e-53	170.2	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
2904404985	411	98.25	3	411	5	398	3.0e-74	244.4	COG0247	Fe-S oxidoreductase	388
2904404986	509	98.45	1	509	9	515	0.0e+00	759.7	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
2904404987	96	74.49	1	96	25	97	3.9e-30	98.7	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
2904404988	310	94.15	1	306	17	322	5.4e-105	345.4	COG0042	tRNA-dihydrouridine synthase	323
2904404989	226	97.16	6	213	6	210	2.4e-50	165.2	COG3222	Uncharacterized conserved protein, glycosyltransferase A (GT-A) superfamily, DUF2064 family	211
2904404990	259	75.09	2	258	54	264	2.8e-46	152.3	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
2904404991	230	43.73	4	227	6	162	6.6e-18	60.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2904404992	197	93.17	1	195	14	204	6.8e-50	164	COG3647	Uncharacterized membrane protein YjdF	205
2904404994	451	83.3	1	451	73	461	0.0e+00	444.4	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904405001	235	61.58	26	192	28	152	1.2e-38	126.2	COG3271	Predicted double-glycine peptidase	201
2904405002	164	98.77	1	162	1	161	5.1e-35	114.9	COG2062	Phosphohistidine phosphatase SixA	163
2904405004	528	92.15	33	528	36	528	0.0e+00	653.5	COG3131	Periplasmic glucans biosynthesis protein	534
2904405006	686	90.9	2	686	59	727	0.0e+00	795.6	COG2943	Membrane glycosyltransferase	736
2904405007	211	81.19	2	194	15	178	1.5e-28	93.6	COG1573	Uracil-DNA glycosylase	202
2904405008	454	94.63	131	347	5	198	5.2e-48	157.2	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2904405009	100	91.51	1	100	2	98	8.0e-31	100.5	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
2904405010	165	57.68	4	165	112	265	2.4e-21	70.8	COG3087	Cell division protein FtsN	264
2904405011	586	97.59	1	586	15	581	0.0e+00	558.6	COG0018	Arginyl-tRNA synthetase	577
2904405013	137	95.08	5	125	6	121	6.8e-35	113.9	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
2904405014	212	86.08	13	201	13	179	7.6e-78	254.1	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
2904405015	596	85.56	14	199	23	176	7.9e-51	166.4	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
2904405015	596	99.75	199	596	2	398	0.0e+00	549.9	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
2904405017	165	93.98	1	161	9	164	1.2e-50	165.4	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2904405018	424	95.05	2	419	19	421	0.0e+00	604.9	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2904405019	892	99.86	1	768	1	730	0.0e+00	651.3	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
2904405020	314	93.09	3	314	21	330	1.3e-123	406.4	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
2904405021	175	88.57	1	168	14	168	2.2e-52	171.3	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
2904405022	165	97.02	1	163	5	167	4.0e-37	121.7	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
2904405023	103	99	4	103	2	100	7.5e-36	116.4	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
2904405024	610	99.51	5	606	3	616	0.0e+00	626.3	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2904405025	509	96.99	1	496	5	487	0.0e+00	560.4	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
2904405026	483	97.9	3	475	4	469	2.0e-129	426.8	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
2904405027	475	91.56	248	475	20	225	1.5e-78	256.9	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2904405028	384	84.34	74	302	39	248	3.3e-50	164.6	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2904405029	744	21.72	210	350	143	243	4.3e-55	31.2	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2904405029	744	24.52	15	148	11	124	4.3e-55	65	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2904405029	744	28.39	345	490	328	459	4.3e-55	96.9	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2904405029	744	75.87	502	742	33	249	2.7e-38	124.9	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2904405032	443	84.02	7	425	3	407	1.2e-33	110.3	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2904405033	331	46.31	106	292	53	165	3.8e-10	32.1	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2904405034	280	43.18	2	259	4	158	1.1e-18	62.6	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2904405035	288	27.16	176	279	201	285	2.5e-11	8.8	COG1216	Glycosyltransferase, GT2 family	305
2904405035	288	42.17	1	152	3	134	2.5e-11	29.5	COG1216	Glycosyltransferase, GT2 family	305
2904405036	403	96.82	7	389	8	403	2.5e-31	103.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904405037	308	92.97	1	306	2	292	3.4e-18	59.8	COG1216	Glycosyltransferase, GT2 family	305
2904405038	426	29.46	229	349	48	151	1.8e-56	43.1	COG1413	HEAT repeat	335
2904405038	426	30.03	23	120	118	223	1.8e-56	62.3	COG1413	HEAT repeat	335
2904405038	426	45.61	99	241	61	221	1.8e-56	104.3	COG1413	HEAT repeat	335
2904405039	174	94.71	10	174	4	164	3.5e-61	200.3	COG1795	Formaldehyde-activating enzyme nesessary for methanogenesis	170
2904405040	451	20.98	188	301	259	348	1.6e-40	52.5	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2904405040	451	22.61	298	418	259	355	1.6e-40	36.8	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2904405040	451	23.78	57	192	246	347	1.6e-40	51.4	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2904405041	174	100	1	148	1	136	2.5e-33	109.3	COG1943	REP element-mobilizing transposase RayT	136
2904405044	490	86.29	18	490	49	388	3.5e-50	164.3	COG0642	Signal transduction histidine kinase	336
2904405046	149	72.67	15	143	38	146	8.4e-05	16.8	COG5652	VanZ like family protein (function unknown)	148
2904405047	243	90.91	1	240	11	200	1.9e-20	68.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904405050	498	90.13	283	498	19	219	5.6e-74	242.1	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
2904405050	498	94.33	1	285	17	299	8.4e-82	268.7	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
2904405051	294	77.07	45	293	1	242	1.4e-85	281.5	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
2904405055	321	58.91	10	134	24	99	9.2e-04	12.7	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2904405055	321	77.27	195	321	24	125	2.3e-23	76.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904405057	174	91.86	1	167	5	162	7.8e-46	150.4	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
2904405058	306	96.35	1	298	6	295	1.5e-41	136.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2904405059	216	94.88	4	215	3	206	2.6e-38	126.2	COG0625	Glutathione S-transferase	211
2904405060	399	83.55	3	387	72	452	6.5e-112	368.8	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2904405061	269	99.32	1	259	2	291	1.4e-68	225.9	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
2904405062	197	93.49	1	194	1	201	3.8e-52	171.4	COG0625	Glutathione S-transferase	211
2904405063	326	97.01	4	298	5	296	1.0e-31	104.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2904405064	476	96.49	11	470	4	443	8.4e-113	371.5	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2904405065	267	76.52	126	263	20	120	3.0e-21	69.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904405067	296	97.34	3	296	1	293	1.4e-64	213	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904405069	261	98.44	2	261	2	254	2.4e-38	126.4	COG4106	Trans-aconitate methyltransferase	257
2904405071	175	89.84	1	174	14	181	7.4e-35	114.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2904405072	322	98.01	13	310	2	296	3.4e-37	122.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904405073	267	98.13	1	256	5	267	1.3e-56	186.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904405080	251	52.33	1	246	35	180	1.8e-13	45.5	COG0500	SAM-dependent methyltransferase	257
2904405081	570	13.32	35	159	308	356	5.5e-12	6.8	COG0457	Tetratricopeptide (TPR) repeat	291
2904405081	570	81.52	122	563	60	359	5.5e-12	32.7	COG0457	Tetratricopeptide (TPR) repeat	291
2904405082	555	99.28	3	554	3	553	0.0e+00	704.5	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2904405083	102	50.62	11	99	4	85	4.6e-24	79.2	COG0440	Acetolactate synthase, small subunit	163
2904405085	397	96.54	1	277	4	282	2.2e-36	119.7	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
2904405086	150	91.5	1	148	12	151	9.1e-48	155.7	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
2904405087	176	92.67	8	158	8	146	2.7e-15	51	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2904405088	658	99.38	1	648	1	642	0.0e+00	841.5	COG1138	Cytochrome c biogenesis factor	648
2904405089	151	96.08	1	151	1	147	1.6e-57	187.6	COG2332	Cytochrome c-type biogenesis protein CcmE	153
2904405090	56	79.1	1	56	5	57	3.7e-16	53.5	COG3114	Heme exporter protein D	67
2904405091	279	48.54	51	262	48	163	5.0e-23	75.5	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2904405092	338	88.74	37	338	34	301	3.7e-64	210.8	COG2813	16S rRNA G1207 methylase RsmC	300
2904405093	899	60.15	598	899	153	389	3.6e-66	218.7	COG0642	Signal transduction histidine kinase	336
2904405096	306	96.95	13	306	3	320	1.7e-55	176.1	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
2904405097	162	98.73	3	162	2	156	7.6e-23	75.5	COG2405	Predicted nucleic acid-binding protein, contains PIN domain	157
2904405098	112	59.09	45	107	30	81	1.2e-14	47.8	COG2886	Predicted antitoxin, contains HTH domain	88
2904405105	914	73.48	91	756	56	598	2.0e-67	222	COG1203	CRISPR/Cas system-associated endonuclease/helicase Cas3	733
2904405106	88	66.67	4	81	29	94	1.4e-08	29.4	COG3668	Plasmid stabilization system protein ParE	98
2904405107	90	66.28	6	80	6	62	6.9e-10	32.8	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
2904405108	787	97.83	4	786	9	775	0.0e+00	994.4	COG0466	ATP-dependent Lon protease, bacterial type	782
2904405109	134	62.33	8	133	20	110	9.5e-21	68	COG0071	Molecular chaperone IbpA, HSP20 family	146
2904405110	580	94.84	40	556	7	484	0.0e+00	495.5	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
2904405111	304	94.14	1	300	14	302	2.8e-106	349.6	COG0109	Polyprenyltransferase (heme O synthase)	304
2904405112	460	96.34	8	442	9	429	4.0e-113	372.4	COG0612	Predicted Zn-dependent peptidase	438
2904405113	437	96.11	12	437	9	428	9.8e-88	288.8	COG0612	Predicted Zn-dependent peptidase	438
2904405114	189	97.87	4	184	2	185	1.6e-57	188.3	COG0742	16S rRNA G966 N2-methylase RsmD	187
2904405115	165	97.48	1	159	4	158	1.5e-66	217.4	COG0669	Phosphopantetheine adenylyltransferase	159
2904405116	82	57.26	1	76	39	109	2.0e-14	47.7	COG1145	Ferredoxin	99
2904405117	784	98.1	47	783	3	621	7.5e-121	398	COG1067	Predicted ATP-dependent protease	647
2904405119	337	98.81	2	337	1	331	0.0e+00	479.7	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
2904405120	478	99.37	1	475	4	478	0.0e+00	571.9	COG0469	Pyruvate kinase	477
2904405121	332	97.87	3	332	4	324	0.0e+00	443.3	COG0158	Fructose-1,6-bisphosphatase	326
2904405122	82	29.83	3	79	27	80	2.3e-03	11.6	COG3038	Cytochrome b561	181
2904405123	241	90.94	2	241	12	242	7.1e-45	147.4	COG3346	Cytochrome oxidase assembly protein ShyY1	252
2904405125	670	86.11	319	669	50	359	3.5e-127	418.6	COG0552	Signal recognition particle GTPase	340
2904405125	670	93.26	1	332	19	336	6.9e-69	226	COG1612	Heme A synthase	323
2904405126	773	40.58	66	381	27	276	3.9e-120	114.6	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
2904405126	773	51.62	412	772	275	592	3.9e-120	276.2	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
2904405127	226	35.14	3	219	79	175	7.5e-06	19.3	COG3031	Type II secretory pathway, component PulC	275
2904405128	210	60.19	20	191	29	155	4.9e-04	13.9	COG3167	Tfp pilus assembly protein PilO	211
2904405129	368	28.85	84	179	55	114	4.6e-13	7.8	COG3166	Tfp pilus assembly protein PilN	206
2904405129	368	67.31	186	358	20	159	4.6e-13	34.3	COG3166	Tfp pilus assembly protein PilN	206
2904405130	304	73.77	5	233	2	240	2.8e-32	105.7	COG3156	Type II secretory pathway, component PulK	323
2904405131	214	49.75	2	198	6	105	1.2e-09	32.4	COG4795	Type II secretory pathway, component PulJ	194
2904405133	139	39.13	1	136	12	83	1.4e-13	44.3	COG4970	Tfp pilus assembly protein FimT	181
2904405134	145	97.44	6	144	5	156	6.5e-31	102.2	COG2165	Type II secretory pathway, pseudopilin PulG	149
2904405135	405	99.5	1	405	1	396	3.2e-120	395.7	COG1459	Type II secretory pathway, component PulF	397
2904405136	586	96.65	87	585	17	507	0.0e+00	605.2	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2904405137	353	93.49	13	346	22	337	2.0e-93	307.1	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
2904405138	255	99.61	1	255	1	258	6.8e-84	275.4	COG0708	Exonuclease III	261
2904405139	106	92.86	1	106	1	104	1.0e-26	87.9	COG0347	Nitrogen regulatory protein PII	112
2904405140	1033	99.61	1	1033	1	1026	0.0e+00	1359.6	COG3696	Cu/Ag efflux pump CusA	1027
2904405141	376	91.03	2	375	21	375	1.9e-35	116.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904405142	417	89.57	13	417	40	451	1.5e-58	192.9	COG1538	Outer membrane protein TolC	457
2904405145	230	97.77	6	230	5	223	1.9e-68	224.6	COG1040	Predicted amidophosphoribosyltransferases	225
2904405146	338	92.01	11	337	12	322	0.0e+00	440.2	COG0502	Biotin synthase or related enzyme	335
2904405147	411	98.97	1	384	3	388	0.0e+00	458.7	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
2904405148	268	93.22	5	265	20	294	1.5e-34	114.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904405149	281	66.95	16	207	11	170	1.5e-28	92.5	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2904405150	235	92.38	4	223	3	208	1.0e-67	222.2	COG0132	Dethiobiotin synthetase	223
2904405151	160	92.68	1	160	8	159	4.6e-24	79.2	COG5488	Uncharacterized membrane protein	164
2904405152	373	92.52	5	287	8	242	3.6e-75	246.2	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2904405153	528	90.16	13	528	6	518	0.0e+00	710.6	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2904405154	158	79.31	1	158	30	190	1.2e-57	188.9	COG3175	Cytochrome c oxidase assembly protein Cox11	195
2904405155	288	94.37	50	288	10	210	1.4e-66	217.9	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2904405156	289	98.26	1	275	3	284	8.5e-89	291.9	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
2904405157	220	95.4	38	212	4	169	5.3e-68	222.5	COG0225	Peptide methionine sulfoxide reductase MsrA	174
2904405158	259	46.39	5	253	35	259	2.5e-42	139.4	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2904405159	438	71.32	70	438	109	389	2.1e-28	93.6	COG0642	Signal transduction histidine kinase	336
2904405160	159	86.81	1	158	25	182	6.1e-70	229	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2904405162	231	65.62	61	203	1	84	1.9e-20	67.2	COG4969	Tfp pilus assembly protein, major pilin PilA	125
2904405163	42	35.04	1	42	75	115	2.2e-12	41.2	COG2361	Uncharacterized conserved protein, contains HEPN domain	117
2904405164	77	88	5	76	2	67	1.0e-18	61.5	COG4456	Virulence-associated protein VagC (function unknown)	74
2904405165	136	96.97	5	135	3	130	3.7e-37	121.7	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
2904405166	88	32	3	85	13	76	1.7e-04	15.2	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
2904405167	80	63.25	1	79	42	115	1.1e-23	77.5	COG2361	Uncharacterized conserved protein, contains HEPN domain	117
2904405168	106	96.91	1	96	1	94	8.2e-22	71.5	COG1669	Predicted nucleotidyltransferase	97
2904405169	197	98.97	1	197	3	195	1.4e-84	276.9	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
2904405170	215	99.51	1	213	1	203	4.1e-78	256.1	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
2904405171	243	98.76	1	243	2	239	1.4e-92	303.5	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
2904405172	254	99.61	1	254	1	256	1.8e-122	401.7	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
2904405173	130	93.75	1	110	6	110	6.1e-44	142.8	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
2904405174	107	97.92	4	101	1	94	3.9e-37	120.7	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
2904405176	190	95.68	3	186	5	181	3.5e-60	196.6	COG1704	Uncharacterized conserved protein	185
2904405177	182	95.48	1	181	4	172	3.5e-62	203.2	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2904405178	277	96.83	2	277	8	282	4.4e-77	253	COG0169	Shikimate 5-dehydrogenase	283
2904405179	326	96.06	1	320	13	329	0.0e+00	490.2	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
2904405180	226	90.1	2	207	21	202	2.1e-48	159	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
2904405181	302	98.68	1	302	5	303	0.0e+00	480.2	COG0408	Coproporphyrinogen III oxidase	303
2904405182	329	59.86	77	324	42	208	1.1e-13	45.7	COG0500	SAM-dependent methyltransferase	257
2904405183	438	98.64	2	438	5	439	0.0e+00	447.2	COG0621	tRNA A37 methylthiotransferase MiaB	437
2904405184	161	90.96	1	161	1	161	4.4e-55	180.2	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
2904405186	422	96.63	1	413	2	402	6.0e-112	369	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
2904405187	166	95.65	5	165	2	155	6.9e-54	176.1	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
2904405188	267	97.39	7	267	3	263	3.1e-106	348.8	COG0413	Ketopantoate hydroxymethyltransferase	268
2904405189	283	99.3	1	283	1	283	3.6e-116	381.4	COG0414	Panthothenate synthetase	285
2904405190	311	98.34	3	298	1	296	1.6e-72	239	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904405191	292	99.65	1	292	1	288	0.0e+00	443.9	COG3954	Phosphoribulokinase	289
2904405192	721	98.51	8	652	3	663	0.0e+00	777.4	COG0210	Superfamily I DNA or RNA helicase	655
2904405196	152	90.41	1	147	2	133	5.0e-51	166.5	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
2904405197	313	98.73	2	313	4	314	6.2e-116	381.6	COG0275	16S rRNA C1402 N4-methylase RsmH	314
2904405198	85	77.88	1	85	22	102	5.2e-27	88.3	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
2904405199	577	97.31	8	563	16	630	0.0e+00	433.3	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2904405200	504	97.52	12	500	11	482	0.0e+00	464.1	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
2904405201	457	99.78	1	452	1	453	0.0e+00	455.7	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
2904405202	360	98.77	20	360	2	323	7.0e-113	371.2	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2904405203	461	98	21	460	7	447	0.0e+00	471.6	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
2904405204	399	95.29	8	389	12	375	2.9e-114	375.8	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
2904405205	358	98.88	3	355	2	355	2.0e-123	406.3	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
2904405206	481	98.05	10	472	4	455	0.0e+00	583.8	COG0773	UDP-N-acetylmuramate-alanine ligase	459
2904405207	310	98.64	19	307	3	292	3.8e-81	266.3	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
2904405208	318	99.06	10	308	2	316	4.4e-90	296.2	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
2904405209	260	87.08	1	242	28	263	9.5e-34	111	COG1589	Cell division septal protein FtsQ	269
2904405210	411	87.1	1	390	4	381	0.0e+00	497.8	COG0849	Cell division ATPase FtsA	418
2904405211	381	91.95	1	364	9	328	0.0e+00	460.4	COG0206	Cell division GTPase FtsZ	338
2904405212	304	96.35	1	301	1	290	5.0e-129	423.9	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
2904405214	907	99.88	2	900	2	840	0.0e+00	1308.6	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
2904405215	403	97.53	2	403	11	405	0.0e+00	503.6	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
2904405216	315	39.73	4	121	13	70	2.2e-13	43.7	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2904405216	315	87.68	127	315	5	189	1.1e-32	107	COG0352	Thiamine monophosphate synthase	211
2904405217	469	99.55	1	469	2	445	0.0e+00	573.1	COG0174	Glutamine synthetase	443
2904405218	357	96.42	2	357	8	357	2.0e-122	402.8	COG3852	Signal transduction histidine kinase, nitrogen specific	363
2904405219	469	98.29	1	469	2	460	0.0e+00	613.5	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904405220	820	99.2	2	814	6	751	0.0e+00	926.9	COG0058	Glucan phosphorylase	750
2904405221	157	98.05	1	154	2	152	5.5e-62	202.5	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
2904405222	334	99.7	1	330	2	329	3.8e-126	415	COG0240	Glycerol-3-phosphate dehydrogenase	329
2904405223	153	92.99	1	153	4	149	3.2e-60	196.6	COG1952	Preprotein translocase subunit SecB	157
2904405224	149	95.61	39	146	5	113	3.1e-28	92.2	COG0607	Rhodanese-related sulfurtransferase	110
2904405225	103	72.88	21	103	19	104	7.8e-17	56	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2904405226	513	99.02	4	513	4	507	0.0e+00	721.4	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
2904405227	295	31.92	150	293	290	425	6.2e-70	180.2	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
2904405227	295	34.98	1	161	103	251	6.2e-70	57.4	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
2904405228	440	90.69	9	410	28	397	1.1e-129	427	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
2904405229	160	96.41	1	160	6	166	7.7e-42	137.1	COG3749	Uncharacterized conserved protein, DUF934 family	167
2904405230	549	99.42	1	545	1	511	0.0e+00	577.4	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2904405231	427	97.17	6	426	7	418	6.6e-70	230	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
2904405232	436	94.98	1	435	6	402	9.4e-85	279	COG1301	Na+/H+-dicarboxylate symporter	415
2904405234	325	78.64	2	86	14	94	3.5e-11	36.3	COG0633	Ferredoxin	102
2904405234	325	81.32	86	316	9	217	8.5e-43	140.2	COG0543	NAD(P)H-flavin reductase	252
2904405235	122	84.96	1	119	6	118	1.2e-30	100.6	COG2346	Truncated hemoglobin YjbI	133
2904405237	107	91.78	1	65	5	71	3.9e-18	59.5	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2904405239	324	91.69	1	300	1	276	1.9e-53	176.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904405240	245	89.93	1	245	14	254	1.7e-64	212	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2904405241	542	99.09	1	538	1	545	0.0e+00	634.9	COG0459	Chaperonin GroEL (HSP60 family)	524
2904405242	96	98.96	1	96	1	95	1.5e-41	134.8	COG0234	Co-chaperonin GroES (HSP10)	96
2904405243	423	17.07	199	373	274	343	8.0e-26	17.4	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2904405243	423	26.34	31	151	3	110	8.0e-26	65.8	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2904405244	106	69.63	7	106	23	116	8.5e-12	39.6	COG2863	Cytochrome c553	121
2904405245	71	14	12	71	4	59	5.9e-03	9.5	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
2904405247	186	33.15	17	171	235	356	1.5e-06	23	COG0457	Tetratricopeptide (TPR) repeat	291
2904405250	280	4.32	14	37	174	191	1.8e-16	1.7	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2904405250	280	43.65	54	268	213	394	1.8e-16	53.2	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2904405251	342	94.55	11	342	16	327	1.3e-51	169.8	COG0714	MoxR-like ATPase	329
2904405253	277	87.73	33	257	3	195	6.5e-16	50.2	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
2904405254	243	97.76	1	241	6	267	6.4e-61	200.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904405255	165	98.14	1	158	3	160	6.0e-43	140.5	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
2904405256	121	98.35	1	119	2	120	1.8e-39	129.1	COG1539	Dihydroneopterin aldolase	121
2904405257	196	98.54	1	193	3	204	1.5e-64	211.8	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
2904405258	345	98.55	1	337	1	339	0.0e+00	446	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
2904405259	77	95.52	1	66	1	64	3.3e-30	98.1	COG0828	Ribosomal protein S21	67
2904405260	149	98.65	2	148	3	148	1.2e-57	188.7	COG1610	Uncharacterized conserved protein YqeY	148
2904405261	575	97.65	4	575	2	583	0.0e+00	536.5	COG0358	DNA primase (bacterial type)	568
2904405262	597	18.48	32	141	47	109	0.0e+00	8.6	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2904405262	597	97.36	174	595	10	341	0.0e+00	431.4	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2904405264	167	86.02	5	167	20	179	8.8e-33	107.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2904405265	334	94.74	2	331	11	316	3.0e-91	299.7	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2904405266	81	88.73	2	69	8	70	1.1e-30	99.4	COG3251	Uncharacterized conserved protein YbdZ, MbtH family	71
2904405267	328	27.35	39	112	20	80	7.2e-40	37	COG2091	Phosphopantetheinyl transferase	223
2904405267	328	42.15	126	250	81	174	7.2e-40	92	COG2091	Phosphopantetheinyl transferase	223
2904405269	3403	60.03	26	487	257	645	0.0e+00	95.7	COG1020	Non-ribosomal peptide synthetase component F	642
2904405269	3403	77.78	638	711	14	76	8.9e-13	17.9	COG0236	Acyl carrier protein	80
2904405269	3403	90.12	3309	3382	6	78	8.9e-13	18.1	COG0236	Acyl carrier protein	80
2904405269	3403	99.85	989	1661	2	648	0.0e+00	507.4	COG1020	Non-ribosomal peptide synthetase component F	642
2904405269	3403	99.85	2529	3188	2	648	0.0e+00	477.7	COG1020	Non-ribosomal peptide synthetase component F	642
2904405270	888	7.92	40	123	20	82	2.1e-109	1.6	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904405270	888	96.23	143	888	31	795	2.1e-109	361.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904405271	470	90.26	5	458	22	401	6.4e-45	147.9	COG2124	Cytochrome P450	411
2904405272	405	87.58	10	405	3	390	2.4e-58	186.4	COG3182	Uncharacterized iron-regulated membrane protein	442
2904405273	1977	34.1	1352	1603	16	236	0.0e+00	13.9	COG1020	Non-ribosomal peptide synthetase component F	642
2904405273	1977	60.81	1047	1116	17	61	2.6e-04	13.4	COG3433	Aryl carrier domain	74
2904405273	1977	81.72	1611	1957	1	313	7.1e-83	272.7	COG3320	Thioester reductase domain of alpha aminoadipate reductase Lys2 and NRPSs	382
2904405273	1977	99.69	280	952	3	648	0.0e+00	528.9	COG1020	Non-ribosomal peptide synthetase component F	642
2904405275	567	95.24	7	553	14	533	0.0e+00	501.2	COG4615	ABC-type siderophore export system, fused ATPase and permease components	546
2904405276	818	97.05	33	806	4	759	0.0e+00	446.2	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
2904405277	477	93.72	28	477	27	444	0.0e+00	488.8	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2904405279	392	96.41	1	378	8	383	3.0e-29	96.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904405280	1124	6.71	1036	1111	944	1011	0.0e+00	41.9	COG0841	Multidrug efflux pump subunit AcrB	1009
2904405280	1124	40.53	22	440	2	412	0.0e+00	272.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2904405280	1124	51.18	457	1019	421	939	0.0e+00	241.9	COG0841	Multidrug efflux pump subunit AcrB	1009
2904405281	329	99.7	1	327	1	327	3.5e-112	368.8	COG2376	Dihydroxyacetone kinase	323
2904405283	212	62.2	1	212	33	236	1.6e-33	110.4	COG2376	Dihydroxyacetone kinase	323
2904405284	263	96.3	1	263	5	264	4.8e-73	240	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
2904405285	212	79.61	1	208	8	249	2.0e-29	93.7	COG0176	Transaldolase	239
2904405287	688	99.1	17	687	3	659	0.0e+00	1070.2	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
2904405288	394	98.48	7	394	2	391	1.1e-122	404.2	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2904405289	788	64.84	646	786	8	125	2.0e-09	31.1	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2904405289	788	65.74	346	637	134	392	5.6e-69	227.9	COG0642	Signal transduction histidine kinase	336
2904405292	245	89.1	39	245	16	203	2.7e-78	256.5	COG2518	Protein-L-isoaspartate O-methyltransferase	209
2904405293	621	41.94	260	574	137	305	1.7e-11	31.6	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904405294	333	24.79	49	225	54	173	1.1e-23	42.8	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904405294	333	27.69	197	333	349	482	1.1e-23	41.8	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904405295	150	90	1	147	1	135	4.6e-41	134.5	COG1959	DNA-binding transcriptional regulator, IscR family	150
2904405296	411	78.6	4	379	4	205	5.1e-71	231.6	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
2904405297	311	95.85	1	306	8	307	8.5e-43	140.8	COG0679	Predicted permease	311
2904405298	244	94.17	5	241	11	236	1.1e-59	195.8	COG0284	Orotidine-5'-phosphate decarboxylase	240
2904405299	317	99.43	1	317	3	353	4.7e-61	200.5	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2904405301	241	90.25	7	237	4	216	3.7e-47	154.9	COG2836	Sulfite exporter TauE/SafE	232
2904405302	313	56.63	1	313	242	557	3.6e-130	429.9	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
2904405303	408	98.26	3	407	3	398	0.0e+00	585.9	COG0137	Argininosuccinate synthase	403
2904405304	439	78.49	6	439	119	556	0.0e+00	441.2	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
2904405305	234	83.85	1	220	15	232	1.0e-44	147.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2904405306	307	96.14	1	254	8	256	2.4e-54	178.9	COG0730	Uncharacterized membrane protein YfcA	258
2904405307	224	94.79	9	213	7	206	4.4e-58	190	COG0352	Thiamine monophosphate synthase	211
2904405309	946	39.13	520	686	100	243	2.4e-56	22.6	COG0457	Tetratricopeptide (TPR) repeat	291
2904405309	946	71.2	23	304	98	359	2.4e-56	56.7	COG0457	Tetratricopeptide (TPR) repeat	291
2904405309	946	84.51	279	592	32	342	2.4e-56	67.1	COG0457	Tetratricopeptide (TPR) repeat	291
2904405309	946	91.58	606	942	5	341	2.4e-56	67.2	COG0457	Tetratricopeptide (TPR) repeat	291
2904405310	249	93.51	15	249	14	229	8.6e-32	104.9	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
2904405311	859	63.05	309	858	225	642	4.5e-105	346.3	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2904405312	525	81.41	71	522	78	423	1.3e-98	325.3	COG0840	Methyl-accepting chemotaxis protein	408
2904405313	551	71.51	101	549	151	534	7.4e-41	133.2	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
2904405314	859	99.14	1	839	4	809	0.0e+00	1209.8	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
2904405315	360	99.19	1	360	3	369	0.0e+00	477.8	COG1932	Phosphoserine aminotransferase	365
2904405316	387	88.96	2	316	35	324	5.2e-78	256	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2904405317	368	93.07	5	105	6	99	3.7e-26	85	COG1605	Chorismate mutase	101
2904405317	368	98.21	97	368	2	276	1.5e-101	333.4	COG0077	Prephenate dehydratase	279
2904405318	371	98.34	6	371	4	358	3.0e-115	379.2	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2904405319	289	98.57	1	283	4	278	7.2e-83	272.3	COG0287	Prephenate dehydrogenase	279
2904405320	442	97.91	5	434	8	428	0.0e+00	471.1	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
2904405321	222	95.98	1	221	4	218	5.7e-80	262.3	COG0283	Cytidylate kinase	222
2904405322	556	97.64	1	548	2	538	0.0e+00	755.9	COG0539	Ribosomal protein S1	541
2904405323	95	97.87	1	94	2	93	2.5e-34	111.8	COG0776	Bacterial nucleoid DNA-binding protein	94
2904405324	101	7.93	9	80	492	553	4.0e-10	32.8	COG2183	Transcriptional accessory protein Tex/SPT6	780
2904405325	202	97.46	8	202	2	193	2.0e-85	279.5	COG0529	Adenylylsulfate kinase or related kinase	197
2904405326	292	97.93	2	292	3	286	5.0e-122	400.8	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
2904405327	540	96.88	2	539	15	542	0.0e+00	605.1	COG0405	Gamma-glutamyltranspeptidase	539
2904405328	268	99.63	1	266	2	267	4.5e-110	361.6	COG0289	Dihydrodipicolinate reductase	266
2904405329	380	99.74	1	377	1	384	0.0e+00	498.8	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2904405330	642	99.17	1	605	5	605	0.0e+00	868.4	COG0443	Molecular chaperone DnaK (HSP70)	579
2904405331	205	95.41	1	195	8	194	2.2e-56	185.1	COG0576	Molecular chaperone GrpE (heat shock protein)	193
2904405332	339	96.81	1	335	11	344	3.5e-103	340	COG1420	Transcriptional regulator of heat shock response	346
2904405333	154	98.09	1	154	1	154	4.9e-68	222.3	COG2193	Bacterioferritin (cytochrome b1)	157
2904405334	226	77.89	1	222	63	284	1.3e-79	261.5	COG0061	NAD kinase	281
2904405335	562	99.46	1	557	1	555	0.0e+00	625.3	COG0497	DNA repair ATPase RecN	557
2904405336	856	98.98	1	489	4	487	0.0e+00	653.5	COG1530	Ribonuclease G or E	487
2904405337	220	70.55	1	209	86	291	1.9e-71	235.2	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2904405338	164	68.47	1	164	68	219	1.5e-34	114.3	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2904405339	329	87.81	19	324	3	283	2.4e-76	251.5	COG0616	Periplasmic serine protease, ClpP class	317
2904405340	201	90.7	34	195	3	158	2.2e-18	60.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2904405343	124	95.35	1	123	7	129	1.0e-62	203.9	COG0048	Ribosomal protein S12	129
2904405344	156	99.32	2	149	2	148	1.1e-63	207.6	COG0049	Ribosomal protein S7	148
2904405345	699	98.9	1	698	3	723	0.0e+00	994.5	COG0480	Translation elongation factor EF-G, a GTPase	697
2904405346	36	8.88	1	36	1	35	1.8e-18	61	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2904405347	329	87.6	10	251	22	240	2.0e-18	59.9	COG2014	Uncharacterized conserved protein, contains DUF4213 and DUF364 domains	250
2904405349	67	8.05	2	61	123	167	1.7e-02	8.1	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
2904405351	82	85.71	1	57	1	54	7.0e-20	65.2	COG2906	Bacterioferritin-associated ferredoxin	63
2904405352	1254	21.4	716	821	290	387	1.7e-35	13.7	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2904405352	1254	30.57	510	683	159	298	1.7e-35	61.6	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2904405352	1254	31	293	484	13	154	1.7e-35	37.9	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2904405352	1254	82.1	921	1199	5	215	8.8e-25	80.6	COG0543	NAD(P)H-flavin reductase	252
2904405353	405	99.48	5	388	2	385	0.0e+00	547.3	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
2904405354	139	96.03	1	130	5	149	1.3e-53	175.2	COG0822	NifU homolog involved in Fe-S cluster formation	150
2904405355	130	97.27	13	122	4	110	1.0e-41	135.6	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2904405356	107	98.18	1	107	3	110	2.8e-41	134.3	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2904405357	179	97.7	9	179	2	171	3.8e-33	109.4	COG1076	DnaJ-domain-containing proteins 1	174
2904405358	620	99.17	11	604	5	605	0.0e+00	649.2	COG0443	Molecular chaperone DnaK (HSP70)	579
2904405359	115	88.35	3	106	1	91	3.7e-28	91.6	COG0633	Ferredoxin	102
2904405360	394	92.74	4	383	1	383	1.2e-114	377.7	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2904405361	120	9.3	11	112	507	562	8.0e-04	12.5	COG4264	Siderophore synthetase component	602
2904405362	108	81.25	47	105	4	55	3.9e-24	78.7	COG3411	(2Fe-2S) ferredoxin	64
2904405364	102	82.52	1	97	13	97	6.0e-21	68.5	COG0633	Ferredoxin	102
2904405365	109	96.19	1	103	3	103	3.9e-42	136.6	COG0278	Glutaredoxin-related protein	105
2904405366	93	98.75	1	80	1	79	4.3e-28	91.7	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
2904405367	78	50	1	72	8	48	1.4e-07	25.9	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
2904405369	241	97.47	1	241	7	237	6.9e-52	170.5	COG2859	Uncharacterized protein	237
2904405374	147	46.37	1	145	146	279	2.7e-12	41.1	COG1276	Putative copper export protein	289
2904405375	102	12.5	8	89	128	187	1.8e-03	11	COG4065	Uncharacterized protein	480
2904405379	521	15.86	1	97	9	80	9.9e-45	42.4	COG1231	Monoamine oxidase	450
2904405379	521	52.64	101	363	207	445	9.9e-45	103.9	COG1231	Monoamine oxidase	450
2904405380	178	97.39	2	176	2	150	6.9e-37	120.6	COG0716	Flavodoxin	151
2904405381	808	98.72	3	786	8	781	0.0e+00	1097.8	COG0466	ATP-dependent Lon protease, bacterial type	782
2904405382	424	98.78	18	424	1	404	0.0e+00	668.7	COG1219	ATP-dependent protease Clp, ATPase subunit	408
2904405383	216	96	15	213	3	194	2.1e-88	289.5	COG0740	ATP-dependent protease ClpP, protease subunit	200
2904405384	126	97.62	1	126	4	126	1.5e-49	161.6	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
2904405385	366	91.56	52	363	6	287	4.4e-61	201.1	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
2904405387	101	58.06	6	101	36	107	9.2e-14	45.5	COG1145	Ferredoxin	99
2904405388	62	81.69	1	61	5	62	1.6e-24	80.1	COG5420	Uncharacterized protein	71
2904405390	140	87.6	1	127	1	106	3.7e-05	17.9	COG1433	Predicted Fe-Mo cluster-binding protein, NifX family	121
2904405391	457	93.45	2	446	22	449	8.7e-99	325.3	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2904405392	562	77.78	494	553	3	51	2.9e-08	27.4	COG2906	Bacterioferritin-associated ferredoxin	63
2904405392	562	98.69	1	465	4	455	2.2e-127	419.7	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2904405393	115	30.1	78	114	64	94	3.8e-13	8.4	COG0633	Ferredoxin	102
2904405393	115	68.93	1	85	2	72	3.8e-13	34.8	COG0633	Ferredoxin	102
2904405394	519	98.47	34	519	5	455	2.1e-119	393.3	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2904405395	489	98.47	25	488	2	452	0.0e+00	487.4	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2904405396	293	98.56	4	281	2	275	0.0e+00	429.4	COG1348	Nitrogenase subunit NifH, an ATPase	278
2904405397	141	25.48	11	136	4	122	1.7e-14	47.6	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904405398	144	88.72	18	144	9	126	4.1e-35	115.1	COG2346	Truncated hemoglobin YjbI	133
2904405401	306	23.89	207	289	234	308	5.3e-50	56.7	COG1397	ADP-ribosylglycohydrolase	314
2904405401	306	58.28	1	201	3	185	5.3e-50	106.1	COG1397	ADP-ribosylglycohydrolase	314
2904405403	109	94.39	1	101	6	106	1.1e-19	64.6	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2904405404	144	95.73	2	115	3	114	1.4e-11	38.8	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2904405406	536	99.54	91	478	2	216	2.3e-13	40	COG0778	Nitroreductase	207
2904405408	256	83.33	8	105	11	105	1.6e-17	57.1	COG0607	Rhodanese-related sulfurtransferase	110
2904405410	228	75.46	5	227	57	262	5.8e-69	226.8	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2904405411	205	98.6	1	203	1	212	5.5e-42	138.3	COG0625	Glutathione S-transferase	211
2904405414	64	98.44	1	64	1	63	1.7e-32	106.2	COG2975	Fe-S-cluster formation regulator IscX/YfhJ	64
2904405415	291	54.46	2	258	151	376	8.7e-22	72.1	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
2904405416	535	98.39	41	535	9	497	0.0e+00	573.5	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
2904405417	297	24.81	202	289	188	254	1.5e-54	39.2	COG3332	Uncharacterized conserved protein, contains NRDE domain	270
2904405417	297	63.7	1	180	1	172	1.5e-54	138.6	COG3332	Uncharacterized conserved protein, contains NRDE domain	270
2904405418	251	57.04	60	194	12	92	1.3e-08	28.9	COG0727	Fe-S-cluster containining protein	132
2904405420	90	93.33	1	90	5	88	3.5e-29	95.4	COG0271	Stress-induced morphogen (activity unknown)	90
2904405423	95	72.82	2	94	14	88	3.1e-16	53.4	COG0633	Ferredoxin	102
2904405424	384	97.87	2	375	4	370	1.5e-101	334.4	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2904405426	70	97.1	1	70	1	67	1.4e-32	105.8	COG5554	Nitrogen fixation protein	69
2904405427	382	97.41	4	382	3	378	0.0e+00	443.8	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
2904405432	190	29.08	24	186	112	218	5.6e-06	19.5	COG0457	Tetratricopeptide (TPR) repeat	291
2904405433	126	97.27	1	109	3	109	1.5e-23	77.1	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2904405434	74	59.68	1	73	38	111	2.6e-11	37.7	COG1145	Ferredoxin	99
2904405435	525	95.81	58	464	2	344	9.2e-67	219.7	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2904405436	154	97.45	1	154	2	154	2.6e-73	239.4	COG2193	Bacterioferritin (cytochrome b1)	157
2904405437	94	88.89	1	94	5	92	4.4e-32	104.9	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
2904405438	229	97.17	1	213	5	210	2.7e-77	253.4	COG4660	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfE subunit	212
2904405439	234	95.38	31	227	8	193	1.4e-55	182.5	COG4659	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit	195
2904405440	359	97.63	4	348	7	336	1.8e-103	340.7	COG4658	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfD subunit	338
2904405441	490	89.04	12	490	5	475	0.0e+00	532.1	COG4656	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfC subunit	529
2904405442	181	88.89	1	180	4	179	9.8e-61	199.3	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
2904405443	193	98.96	1	193	1	191	1.5e-91	300.2	COG4657	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfA subunit	193
2904405444	93	6.93	15	52	30	43	2.0e-02	4.6	COG1326	Uncharacterized archaeal Zn-finger protein	201
2904405444	93	20.3	31	85	8	48	2.0e-02	5	COG1326	Uncharacterized archaeal Zn-finger protein	201
2904405445	107	94.39	1	102	6	106	3.5e-24	79.1	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2904405447	447	97.51	29	447	8	398	5.4e-50	164.6	COG0247	Fe-S oxidoreductase	388
2904405449	541	94.55	2	541	30	549	0.0e+00	553	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2904405450	275	90.82	37	237	6	183	4.1e-80	261.9	COG1045	Serine acetyltransferase	194
2904405451	370	91.54	1	365	9	300	1.1e-39	131	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2904405455	414	54.32	45	296	47	197	4.3e-06	20.3	COG1082	Sugar phosphate isomerase/epimerase	274
2904405456	292	99.21	2	259	2	253	2.5e-83	273.4	COG1099	Predicted metal-dependent hydrolase, TIM-barrel fold	254
2904405458	292	16.9	184	281	144	192	1.5e-25	4	COG0382	4-hydroxybenzoate polyprenyltransferase	289
2904405458	292	58.97	4	177	12	182	1.5e-25	84.3	COG0382	4-hydroxybenzoate polyprenyltransferase	289
2904405459	282	97.48	1	279	3	273	5.6e-47	152.4	COG1082	Sugar phosphate isomerase/epimerase	274
2904405460	714	93.33	6	714	54	795	5.9e-64	210.6	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904405461	828	23.44	29	187	283	387	3.7e-13	8.1	COG2425	Uncharacterized protein, contains a von Willebrand factor type A (vWA) domain	437
2904405461	828	35.71	360	557	260	419	3.7e-13	33	COG2425	Uncharacterized protein, contains a von Willebrand factor type A (vWA) domain	437
2904405463	299	55.4	13	294	177	407	3.5e-36	119.4	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2904405464	340	94.24	17	338	13	323	4.8e-86	283	COG0714	MoxR-like ATPase	329
2904405470	411	79.84	4	389	62	362	5.7e-52	171.4	COG1260	Myo-inositol-1-phosphate synthase	362
2904405471	472	96.15	1	470	5	453	0.0e+00	546.6	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904405472	474	87.56	127	473	44	388	9.8e-58	191	COG0642	Signal transduction histidine kinase	336
2904405475	224	38.41	22	204	85	190	5.4e-05	15.6	COG3031	Type II secretory pathway, component PulC	275
2904405476	205	28.85	4	114	29	88	2.2e-06	9.8	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2904405476	205	43.75	110	202	113	203	2.2e-06	17.3	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2904405478	330	49.82	91	325	42	180	1.6e-04	16.4	COG0500	SAM-dependent methyltransferase	257
2904405481	499	12.75	130	303	110	154	7.2e-29	7.5	COG1413	HEAT repeat	335
2904405481	499	65.44	268	496	37	267	7.2e-29	93.2	COG1413	HEAT repeat	335
2904405482	2428	9.35	1703	1789	33	112	6.4e-105	45.4	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904405482	2428	10.86	1385	1501	36	128	6.4e-105	56.8	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904405482	2428	11.21	1496	1598	36	131	6.4e-105	36.6	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904405482	2428	11.33	1186	1314	71	167	6.4e-105	35.6	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904405482	2428	11.92	1598	1712	32	133	6.4e-105	57.5	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904405482	2428	16.59	1305	1449	20	161	6.4e-105	77	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904405482	2428	19.98	1782	1984	31	201	6.4e-105	62.2	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904405482	2428	29.44	1988	2234	423	674	6.4e-105	50.5	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904405482	2428	70.92	611	893	25	241	2.7e-51	166.2	COG2815	PASTA domain, binds beta-lactams	303
2904405485	455	83.68	1	430	40	439	4.7e-35	115.5	COG1524	Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily	450
2904405490	467	97.92	1	462	9	478	0.0e+00	520.6	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2904405491	268	75.43	1	257	20	237	6.0e-44	144.2	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
2904405493	91	88.04	1	91	9	89	5.4e-28	91.6	COG2257	Type III secretion system substrate exporter, FlhB-like	92
2904405494	223	98.65	1	223	2	220	1.1e-80	264.5	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
2904405495	213	98.62	2	209	3	216	7.7e-45	147.9	COG0602	Organic radical activating enzyme	212
2904405496	283	81.44	7	278	48	262	2.4e-52	170.1	COG1729	Periplasmic TolA-binding protein (function unknown)	262
2904405497	193	90.95	2	193	17	197	8.8e-40	131.3	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2904405498	429	99.07	8	429	3	427	6.8e-125	411.8	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2904405499	475	19.59	390	474	313	388	1.1e-17	20.2	COG3064	Membrane protein involved in colicin uptake	387
2904405499	475	22.94	290	399	142	230	1.1e-17	6.6	COG3064	Membrane protein involved in colicin uptake	387
2904405499	475	23.97	219	311	131	223	1.1e-17	11.5	COG3064	Membrane protein involved in colicin uptake	387
2904405499	475	24.23	156	246	111	204	1.1e-17	11.5	COG3064	Membrane protein involved in colicin uptake	387
2904405499	475	30.93	47	174	93	212	1.1e-17	17.6	COG3064	Membrane protein involved in colicin uptake	387
2904405500	148	94.24	4	147	7	137	4.6e-43	140.8	COG0848	Biopolymer transport protein ExbD	137
2904405501	225	98.61	10	225	2	214	1.2e-70	232.2	COG0811	Biopolymer transport protein ExbB/TolQ	216
2904405502	141	95.68	5	140	3	135	6.9e-46	149.9	COG0824	Acyl-CoA thioesterase FadM	137
2904405503	342	99.1	3	334	3	331	0.0e+00	535.6	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
2904405504	186	91	1	186	14	195	3.0e-18	59.9	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
2904405505	198	99	1	197	1	199	1.6e-63	208.1	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
2904405506	168	97.52	5	163	1	157	8.1e-58	189	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
2904405507	248	99.59	1	242	1	242	2.6e-101	332.5	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
2904405508	743	99.18	9	743	3	727	0.0e+00	870.4	COG2217	Cation transport ATPase	713
2904405509	349	94.8	2	345	17	344	6.6e-114	374.8	COG2957	Agmatine/peptidylarginine deiminase	346
2904405510	296	97.84	3	293	2	273	6.8e-78	255.7	COG0388	Predicted amidohydrolase	274
2904405511	107	81.25	4	106	25	128	4.4e-16	53.8	COG2916	DNA-binding protein H-NS	128
2904405512	1160	98.68	18	1160	11	1135	0.0e+00	1457.9	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
2904405513	336	98.27	1	335	5	344	6.9e-130	427.6	COG2899	Uncharacterized protein	346
2904405515	554	68.89	6	539	1	403	0.0e+00	519.5	COG2812	DNA polymerase III, gamma/tau subunits	515
2904405516	107	94.29	1	104	7	105	1.2e-39	129	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
2904405517	198	97.98	1	198	4	197	3.0e-78	256	COG0353	Recombinational DNA repair protein RecR	198
2904405518	114	76.6	2	114	2	109	9.9e-33	107.3	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2904405521	575	94.25	5	450	6	382	3.0e-87	287.1	COG0475	Kef-type K+ transport system, membrane component KefB	397
2904405522	363	99.43	1	363	1	348	0.0e+00	441.8	COG3839	ABC-type sugar transport system, ATPase component	338
2904405523	691	27.27	267	463	19	141	1.3e-20	38.1	COG5368	Uncharacterized protein	451
2904405523	691	33.48	542	691	281	431	1.3e-20	27.9	COG5368	Uncharacterized protein	451
2904405526	365	94.46	2	365	17	323	1.9e-101	333.5	COG0379	Quinolinate synthase	324
2904405527	150	96.79	1	150	6	156	9.2e-56	182.7	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
2904405528	199	97.94	4	195	3	192	1.0e-65	215	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
2904405529	484	98.36	2	484	3	483	0.0e+00	551.6	COG1530	Ribonuclease G or E	487
2904405530	1291	98.74	5	1264	10	1264	0.0e+00	653	COG3164	Uncharacterized conserved protein YhdP, contains DUF3971 and AsmA2 domains	1271
2904405531	273	94.6	2	273	5	267	7.2e-78	255.8	COG0388	Predicted amidohydrolase	274
2904405532	481	98.68	22	479	6	455	0.0e+00	520.7	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2904405533	450	98.9	16	450	5	455	1.0e-124	411	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2904405534	371	91.44	5	371	33	406	1.3e-39	131.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904405535	435	84.85	16	434	8	416	2.7e-41	135.7	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2904405536	282	51.61	55	275	14	157	1.0e-03	13.3	COG0500	SAM-dependent methyltransferase	257
2904405537	299	67.13	2	290	5	245	4.7e-31	103.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2904405538	301	54.51	50	237	32	164	5.6e-13	42.7	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2904405539	356	74.57	1	337	85	389	2.0e-19	64.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904405540	322	76.12	4	304	16	270	4.1e-25	82.9	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2904405541	268	35.46	153	214	89	138	1.5e-12	35.1	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2904405541	268	54.61	33	137	13	89	1.5e-12	8.3	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2904405542	555	99.06	15	551	4	532	0.0e+00	726.9	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
2904405543	68	89.39	1	64	7	65	1.2e-13	45.3	COG1724	Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family	66
2904405544	67	73.97	1	65	2	55	4.6e-20	65.7	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
2904405545	462	90.27	22	462	27	295	7.0e-67	218.9	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2904405546	61	65.75	2	58	2	49	2.0e-04	15.4	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
2904405547	325	99.37	1	325	1	316	8.0e-66	216.9	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2904405548	746	95.5	25	703	14	565	1.5e-63	209.7	COG0747	ABC-type transport system, periplasmic component	556
2904405549	260	98.46	1	259	1	255	2.6e-118	388.3	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
2904405550	458	30.96	323	457	215	327	2.6e-23	44.1	COG1858	Cytochrome c peroxidase	364
2904405550	458	60.82	19	339	69	290	2.6e-23	27.1	COG1858	Cytochrome c peroxidase	364
2904405551	203	99.01	1	201	1	201	5.7e-63	206.4	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2904405552	215	52.87	14	195	31	168	1.8e-12	40.8	COG4544	Uncharacterized conserved protein	260
2904405554	247	85.41	18	246	32	230	4.0e-13	42.4	COG5581	c-di-GMP-binding flagellar brake protein YcgR, contains PilZNR and PilZ domains	233
2904405555	493	92.51	217	478	19	265	2.3e-61	201.5	COG1526	Formate dehydrogenase assembly factor FdhD	266
2904405555	493	97.42	4	197	3	191	1.2e-61	201.4	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
2904405556	152	79.71	20	150	9	118	4.2e-16	53	COG3439	Uncharacterized conserved protein, DUF302 family	137
2904405558	254	90.77	1	227	21	256	1.8e-49	162.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2904405560	1237	18.78	702	882	290	375	1.7e-30	13.8	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2904405560	1237	30.79	279	468	13	153	1.7e-30	25	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2904405560	1237	39.08	503	691	159	337	1.7e-30	58	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2904405560	1237	80.93	903	1176	9	216	1.0e-22	73.9	COG0543	NAD(P)H-flavin reductase	252
2904405562	414	99.51	9	414	2	407	0.0e+00	553.3	COG0538	Isocitrate dehydrogenase	407
2904405563	525	99.03	1	522	5	517	0.0e+00	555	COG2918	Gamma-glutamylcysteine synthetase	518
2904405565	201	87.56	1	200	6	188	3.3e-14	48.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904405566	249	97.32	1	247	4	257	1.0e-84	277.9	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
2904405567	304	97.44	1	304	4	269	1.1e-32	107.6	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2904405568	241	94.63	4	239	8	236	1.1e-75	248.3	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
2904405569	93	69.52	7	85	28	100	1.0e-03	13.8	COG3906	Uncharacterized protein YrzB, UPF0473 family	105
2904405570	376	93.02	5	341	23	355	1.4e-70	232.4	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2904405573	194	97.38	3	193	3	188	2.0e-74	243.7	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
2904405574	316	92.2	12	309	6	277	3.7e-43	142.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904405575	302	96.61	3	300	5	232	1.4e-04	13.4	COG3637	Opacity protein and related surface antigens	199
2904405576	321	98.95	10	321	2	283	2.0e-95	313.5	COG2301	Citrate lyase beta subunit	283
2904405577	389	99.22	1	389	2	381	0.0e+00	498.7	COG0045	Succinyl-CoA synthetase, beta subunit	387
2904405578	296	99.32	1	292	1	292	7.1e-120	394	COG0074	Succinyl-CoA synthetase, alpha subunit	293
2904405579	107	96.49	1	107	3	112	2.4e-26	86.4	COG0607	Rhodanese-related sulfurtransferase	110
2904405580	151	98.62	1	145	2	144	2.0e-60	197.7	COG1490	D-Tyr-tRNAtyr deacylase	145
2904405581	167	59.5	5	166	95	238	3.8e-17	55.8	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2904405582	444	99.08	11	437	5	436	2.3e-119	393.4	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
2904405583	296	98.68	2	292	4	301	3.3e-111	365.4	COG0031	Cysteine synthase	300
2904405584	448	99.14	1	396	3	349	0.0e+00	483.1	COG0826	Collagenase-like protease, PrtC family	347
2904405586	161	76.42	1	161	12	173	9.6e-46	150.4	COG0684	Regulator of RNase E activity RraA	210
2904405587	188	97.3	2	183	3	182	1.1e-68	224.8	COG2096	Cob(I)alamin adenosyltransferase	184
2904405588	312	98.31	1	295	2	291	8.6e-129	423	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
2904405589	633	71.03	281	629	126	434	6.0e-79	259.7	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2904405589	633	79.58	3	276	17	246	7.2e-32	104.1	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
2904405590	424	82.49	7	368	64	388	1.3e-64	213.3	COG0642	Signal transduction histidine kinase	336
2904405591	142	89.47	1	138	6	124	1.6e-24	80.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2904405592	491	65.99	89	489	128	387	2.2e-61	202.7	COG0642	Signal transduction histidine kinase	336
2904405593	566	97.47	2	564	6	506	0.0e+00	574	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2904405594	595	98.83	12	595	8	597	0.0e+00	625.7	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
2904405595	693	96.24	36	683	1	588	0.0e+00	780.4	COG1966	Carbon starvation protein CstA	575
2904405596	538	91.53	56	538	37	425	6.9e-94	309.6	COG0840	Methyl-accepting chemotaxis protein	408
2904405597	606	64.4	108	600	215	641	6.2e-127	418.5	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2904405598	392	97.98	6	389	5	392	3.0e-98	323.7	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2904405599	441	97.64	4	431	4	417	2.3e-125	412.5	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2904405600	236	96.31	1	235	9	243	6.0e-94	308.1	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2904405601	225	97.75	5	223	4	220	2.7e-49	162.4	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2904405602	240	79.1	4	236	2	213	5.1e-42	138.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904405603	184	90.27	74	184	10	111	3.3e-34	111.1	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
2904405604	179	80.93	1	179	42	215	7.2e-51	167.4	COG3122	Uncharacterized conserved protein YaiL, DUF2058 family	215
2904405605	386	47.78	3	202	8	190	3.2e-14	22.8	COG0477	MFS family permease	338
2904405605	386	49.61	192	384	6	195	3.2e-14	31.4	COG0477	MFS family permease	338
2904405606	366	97.84	2	361	2	363	0.0e+00	533.4	COG0082	Chorismate synthase	369
2904405607	203	92.76	22	202	11	215	3.2e-27	84.7	COG2755	Lysophospholipase L1 or related esterase	216
2904405608	307	97.21	12	299	1	279	7.1e-64	209.9	COG2890	Methylase of polypeptide chain release factors	280
2904405609	343	99.71	1	343	2	349	1.5e-127	419.9	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
2904405610	117	96.81	2	95	2	92	1.2e-36	119.1	COG0776	Bacterial nucleoid DNA-binding protein	94
2904405611	792	100	143	791	1	652	0.0e+00	684.5	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
2904405612	341	98.52	1	337	6	337	8.5e-124	407.7	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
2904405613	115	95.76	1	115	1	113	5.4e-56	182.2	COG0292	Ribosomal protein L20	118
2904405614	65	98.46	1	65	1	64	1.1e-29	97.3	COG0291	Ribosomal protein L35	65
2904405615	143	81.25	1	143	34	176	6.5e-64	209	COG0290	Translation initiation factor IF-3	176
2904405616	638	98.82	34	638	2	588	0.0e+00	886.9	COG0441	Threonyl-tRNA synthetase	589
2904405618	181	85.86	3	181	11	174	5.9e-36	117.7	COG3065	Starvation-inducible outer membrane lipoprotein	191
2904405619	136	53.4	2	122	39	140	6.6e-16	52.2	COG3065	Starvation-inducible outer membrane lipoprotein	191
2904405620	400	84.14	1	255	43	286	2.0e-82	270.9	COG1398	Fatty-acid desaturase	289
2904405621	142	76	11	138	7	101	9.0e-16	52.7	COG3293	Transposase	124
2904405622	137	88.8	1	132	7	117	4.9e-09	31	COG3293	Transposase	124
2904405623	545	98.91	1	537	1	544	0.0e+00	634	COG0459	Chaperonin GroEL (HSP60 family)	524
2904405624	97	98.96	2	97	1	95	4.8e-40	130.1	COG0234	Co-chaperonin GroES (HSP10)	96
2904405625	322	98.72	1	322	4	312	6.1e-52	171.3	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2904405627	98	55.95	1	82	2	48	1.1e-11	39.2	COG4118	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor	84
2904405628	140	96.15	1	134	1	125	3.7e-36	118.2	COG3744	PIN domain nuclease, a component of toxin-antitoxin system (PIN domain)	130
2904405632	331	79.15	1	273	5	228	3.2e-39	128	COG3649	CRISPR/Cas system type I-B associated protein Csh2, Cas7 group, RAMP superfamily	283
2904405633	213	91.88	8	191	16	196	2.1e-24	80.8	COG1468	CRISPR/Cas system-associated exonuclease Cas4, RecB family	190
2904405634	344	98.17	3	343	4	325	1.3e-79	262	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
2904405635	96	88.76	1	90	1	79	1.6e-23	77.2	COG1343	CRISPR/Cas system-associated endoribonuclease Cas2	89
2904405636	390	96.46	3	390	12	393	6.9e-99	326.1	COG3213	Uncharacterized protein involved in response to NO	396
2904405637	120	97.44	1	114	3	116	1.5e-42	139.1	COG3189	Uncharacterized conserved protein YeaO, DUF488 family	117
2904405638	109	92.66	1	109	3	103	4.3e-40	130.7	COG4517	Uncharacterized protein	109
2904405639	130	77.42	1	130	5	124	4.2e-52	170	COG2969	Stringent starvation protein B	155
2904405640	205	97.21	1	198	1	209	1.5e-45	149.9	COG0625	Glutathione S-transferase	211
2904405641	240	84.84	11	240	43	277	1.5e-48	160	COG2857	Cytochrome c1	250
2904405642	473	99.75	3	405	2	405	0.0e+00	532.4	COG1290	Cytochrome b subunit of the bc complex	381
2904405643	197	88.33	3	196	12	170	1.3e-47	156.1	COG0723	Rieske Fe-S protein	177
2904405644	363	98.61	11	363	3	358	3.9e-98	322.8	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2904405645	437	95.34	7	437	18	426	0.0e+00	565.8	COG0141	Histidinol dehydrogenase	425
2904405646	214	75.09	1	213	2	221	1.9e-69	228.5	COG0040	ATP phosphoribosyltransferase	290
2904405647	421	99.29	1	421	1	418	0.0e+00	610.9	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
2904405648	114	87.88	10	103	12	98	5.7e-17	56.1	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
2904405649	166	41.35	2	165	3	155	2.1e-44	146.4	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2904405650	260	95.88	1	260	9	264	1.5e-95	313.8	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2904405651	279	97.34	7	271	6	261	4.8e-107	351.3	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
2904405652	240	27.91	4	226	60	258	2.1e-61	202.5	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2904405653	87	19.49	2	86	25	108	1.9e-03	11.1	COG0172	Seryl-tRNA synthetase	429
2904405654	282	97.52	3	282	3	277	5.2e-89	292.3	COG0421	Spermidine synthase	282
2904405655	624	96.17	1	624	24	650	0.0e+00	841.6	COG1166	Arginine decarboxylase (spermidine biosynthesis)	652
2904405656	294	98.6	9	291	3	284	2.2e-93	306.9	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2904405657	426	86.46	2	419	5	387	1.0e-51	162.8	COG3182	Uncharacterized iron-regulated membrane protein	442
2904405659	763	95.22	16	763	37	793	9.8e-54	177.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904405660	235	80.29	14	235	53	272	8.3e-32	105.1	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2904405661	220	92.59	4	213	9	208	5.1e-56	184.3	COG0811	Biopolymer transport protein ExbB/TolQ	216
2904405662	135	97.12	1	135	1	135	3.8e-42	138	COG0848	Biopolymer transport protein ExbD	137
2904405663	336	97.03	20	219	7	202	2.3e-79	259.4	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
2904405664	178	95.88	9	177	2	164	2.3e-68	223.3	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
2904405665	191	95.72	4	191	5	183	1.5e-23	77.8	COG3117	Lipopolysaccharide export system protein LptC	188
2904405666	233	92.49	67	233	7	166	3.3e-37	121.8	COG1934	Lipopolysaccharide export system protein LptA	173
2904405667	241	99.18	1	241	3	243	9.3e-117	382.8	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
2904405668	487	99.78	1	487	1	447	0.0e+00	539.5	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
2904405669	95	88.18	1	95	1	97	1.7e-34	112.9	COG1544	Ribosome-associated translation inhibitor RaiA	110
2904405670	285	98.95	1	285	1	283	2.9e-106	349.3	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
2904405671	409	24.86	75	255	104	194	1.4e-06	11.9	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2904405671	409	25.96	263	382	255	349	1.4e-06	7.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2904405672	321	35.48	171	321	174	316	7.0e-43	46.8	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904405672	321	51.86	17	211	46	254	7.0e-43	101.6	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904405673	247	74.84	5	246	4	232	6.7e-73	240.1	COG1131	ABC-type multidrug transport system, ATPase component	293
2904405674	269	68.26	11	258	81	280	8.8e-17	55.3	COG0842	ABC-type multidrug transport system, permease component	286
2904405675	356	98.57	5	355	1	345	0.0e+00	526.6	COG1088	dTDP-D-glucose 4,6-dehydratase	340
2904405676	297	98.63	6	293	2	288	1.8e-125	412	COG1209	dTDP-glucose pyrophosphorylase	286
2904405677	185	97.74	1	174	5	177	3.7e-71	232.6	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
2904405678	306	99.29	1	301	1	280	2.7e-97	319.5	COG1091	dTDP-4-dehydrorhamnose reductase	281
2904405679	1172	99.83	6	1170	2	1156	0.0e+00	1442.2	COG0587	DNA polymerase III, alpha subunit	1139
2904405680	454	93.48	4	436	28	457	7.9e-84	276.2	COG1538	Outer membrane protein TolC	457
2904405681	657	97.5	56	656	11	596	0.0e+00	752.5	COG0465	ATP-dependent Zn proteases	596
2904405682	172	89.78	30	170	8	130	1.1e-08	28.4	COG4319	Ketosteroid isomerase homolog	137
2904405684	284	41.02	31	275	24	144	4.7e-11	37.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904405685	124	61.83	15	122	29	109	1.6e-12	41.6	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2904405686	241	52.37	1	228	3	190	4.9e-26	87	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2904405687	349	96.81	6	347	3	336	0.0e+00	468.9	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
2904405688	317	76.97	1	303	38	301	6.7e-31	101.9	COG3249	Uncharacterized protein	343
2904405689	189	89.69	2	182	13	186	7.5e-26	85.5	COG0558	Phosphatidylglycerophosphate synthase	192
2904405691	349	93.26	15	347	16	333	2.4e-46	152	COG1612	Heme A synthase	323
2904405694	700	4.62	292	326	10	25	7.2e-40	3.3	COG1816	Adenosine deaminase	345
2904405694	700	76.3	402	694	79	342	7.2e-40	126.1	COG1816	Adenosine deaminase	345
2904405695	194	57.64	29	188	47	163	1.1e-22	74.9	COG4112	Predicted phosphoesterase, NUDIX family	203
2904405697	160	55	4	145	38	147	3.9e-12	40.1	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
2904405698	543	85.09	9	382	3	316	7.5e-19	62	COG1332	CRISPR/Cas system CSM-associated protein Csm5, group 7 of RAMP superfamily	369
2904405699	323	25.08	166	273	184	262	1.3e-06	15.2	COG1567	CRISPR/Cas system CSM-associated protein Csm4, group 5 of RAMP superfamily	313
2904405699	323	26.98	4	120	24	108	1.3e-06	5.3	COG1567	CRISPR/Cas system CSM-associated protein Csm4, group 5 of RAMP superfamily	313
2904405700	132	97.73	1	132	2	130	8.0e-36	117.7	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
2904405702	238	82.42	1	230	7	217	1.8e-55	182.4	COG1337	CRISPR/Cas system CSM-associated protein Csm3, group 7 of RAMP superfamily	249
2904405703	164	82.61	24	164	23	136	7.5e-11	35.8	COG1421	CRISPR/Cas system CSM-associated protein Csm2, small subunit	137
2904405707	941	99.77	3	897	2	869	0.0e+00	1263.3	COG1048	Aconitase A	861
2904405708	476	99.78	19	476	2	463	0.0e+00	600	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
2904405709	151	99.27	15	151	2	137	2.4e-31	103.2	COG1371	SHS2 domain protein implicated in nucleic acid metabolism	137
2904405711	599	17.3	35	143	51	109	2.5e-129	11	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2904405711	599	97.07	242	597	11	341	2.5e-129	415.9	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2904405713	571	92.59	4	568	23	584	9.4e-122	401.6	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
2904405716	409	94.74	1	409	6	401	5.0e-123	405.3	COG1301	Na+/H+-dicarboxylate symporter	415
2904405717	839	59.34	710	838	11	118	2.3e-10	31.9	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2904405717	839	77.92	298	700	85	391	1.1e-71	236.1	COG0642	Signal transduction histidine kinase	336
2904405722	166	90	1	165	2	145	3.7e-10	33.4	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
2904405723	244	87.96	58	244	3	192	3.8e-20	66.1	COG0778	Nitroreductase	207
2904405727	276	91.67	1	264	9	272	4.1e-64	210.5	COG0682	Prolipoprotein diacylglyceryltransferase	287
2904405728	274	86.67	25	273	25	258	1.7e-50	165.9	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2904405729	294	97.47	4	290	2	309	1.7e-61	202.2	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2904405730	239	94.31	11	225	5	203	6.5e-78	255.3	COG2518	Protein-L-isoaspartate O-methyltransferase	209
2904405731	131	94.17	5	128	3	115	1.9e-23	77.3	COG1734	RNA polymerase-binding transcription factor DksA	120
2904405732	412	99.26	3	412	3	404	2.1e-129	426.2	COG4198	Uncharacterized conserved protein, DUF1015 family	405
2904405733	177	17.53	48	176	348	432	3.8e-06	20.2	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2904405734	643	98.23	10	640	11	676	0.0e+00	507.2	COG1199	Rad3-related DNA helicase	654
2904405735	229	99.1	1	225	1	219	1.0e-56	186.6	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
2904405736	206	95.28	2	206	2	203	6.1e-63	206	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
2904405737	216	87.29	1	215	16	221	7.1e-37	121.6	COG1994	Zn-dependent protease (includes SpoIVFB)	230
2904405738	296	95.97	58	295	2	239	4.4e-69	227.1	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
2904405739	194	92.93	1	180	8	178	4.7e-63	206.4	COG1386	Chromosome segregation and condensation protein ScpB	184
2904405740	295	97.97	23	267	3	243	2.7e-76	250.3	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2904405741	299	89.07	97	296	20	182	6.9e-54	176.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904405746	147	69.76	1	145	46	188	1.3e-34	113.5	COG2078	Uncharacterized conserved protein, AMMECR1 domain	203
2904405747	261	99.27	2	261	2	274	8.5e-57	186.4	COG1355	Predicted class III extradiol dioxygenase, MEMO1 family	279
2904405748	369	99.19	59	308	3	248	1.2e-70	231.7	COG1180	Pyruvate-formate lyase-activating enzyme	260
2904405749	531	96.15	1	530	8	507	0.0e+00	686.5	COG0029	Aspartate oxidase	518
2904405750	190	95.16	5	189	2	178	8.5e-51	166.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2904405751	173	39.44	1	125	3	86	1.4e-12	41.1	COG3073	Negative regulator of sigma E activity	213
2904405752	316	90.31	2	313	29	317	2.0e-59	195.6	COG3026	Negative regulator of sigma E activity	320
2904405753	146	95.33	1	146	1	143	4.8e-25	82.6	COG3086	Positive regulator of sigma E activity	150
2904405754	468	25.21	377	468	267	358	1.7e-126	41.9	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2904405754	468	90.14	4	362	35	363	1.7e-126	377.9	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2904405755	601	99.17	1	600	5	602	0.0e+00	1030.1	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
2904405756	257	84.09	32	240	7	154	5.7e-35	110.2	COG0681	Signal peptidase I	166
2904405758	240	94.49	14	238	10	232	4.1e-77	252.6	COG0571	dsRNA-specific ribonuclease	235
2904405759	293	98.32	1	293	4	296	5.9e-118	387.7	COG1159	GTPase Era, involved in 16S rRNA processing	298
2904405760	191	78.17	1	191	50	246	1.0e-36	120.9	COG1381	Recombinational DNA repair protein (RecF pathway)	251
2904405761	251	98.77	8	247	2	241	1.9e-107	352.4	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
2904405763	421	90.16	154	406	17	181	6.8e-50	163.8	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904405764	315	92.62	1	313	17	317	4.5e-89	293.1	COG0042	tRNA-dihydrouridine synthase	323
2904405765	160	80.2	1	160	39	196	1.0e-75	247.7	COG0302	GTP cyclohydrolase I	195
2904405766	330	98.13	6	330	5	319	2.1e-106	349.9	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
2904405767	286	93.43	3	281	14	283	5.8e-44	144.2	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
2904405768	612	67.87	118	608	190	639	9.4e-85	279.1	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2904405769	777	87.8	91	766	18	643	0.0e+00	615.2	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2904405770	636	62.88	4	618	317	853	2.9e-26	79.7	COG3170	Tfp pilus assembly protein FimV	755
2904405772	340	99.4	4	336	2	335	0.0e+00	436.8	COG0136	Aspartate-semialdehyde dehydrogenase	334
2904405773	362	99.14	1	360	2	346	0.0e+00	446.2	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2904405774	213	97.93	1	209	1	189	3.9e-78	255.9	COG0066	3-isopropylmalate dehydratase small subunit	191
2904405775	522	99.53	1	468	2	428	0.0e+00	631.3	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
2904405776	214	99.46	1	214	1	184	3.8e-71	233.4	COG0563	Adenylate kinase or related kinase	178
2904405777	123	88.37	1	122	12	125	1.5e-22	74.2	COG2149	Uncharacterized membrane protein YidH, DUF202 family	120
2904405779	479	99.34	22	477	2	456	0.0e+00	591.9	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2904405780	1543	10.84	638	696	354	406	0.0e+00	4.6	COG0069	Glutamate synthase domain 2	485
2904405780	1543	97.7	1212	1543	2	298	5.3e-115	378	COG0070	Glutamate synthase domain 3	301
2904405780	1543	99.18	714	1206	3	487	0.0e+00	730.3	COG0069	Glutamate synthase domain 2	485
2904405780	1543	100	10	396	1	372	0.0e+00	517.2	COG0067	Glutamate synthase domain 1	371
2904405781	405	99.49	3	392	2	392	1.3e-108	358.2	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2904405782	129	59.74	1	112	11	102	1.2e-04	16.1	COG3133	Outer membrane lipoprotein SlyB	154
2904405783	513	96.13	1	508	11	556	0.0e+00	437.8	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2904405784	484	97.73	1	484	9	482	0.0e+00	444.6	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2904405785	117	100	1	115	1	126	3.4e-27	89.2	COG1553	Sulfur relay (sulfurtransferase) complex TusBCD TusD component, DsrE family	126
2904405786	119	97.46	2	119	2	116	7.5e-25	81.6	COG2923	Sulfur relay (sulfurtransferase) complex TusC component, DsrF/TusC family	118
2904405787	102	100	3	101	1	96	3.4e-20	66.2	COG2168	Sulfur transfer complex TusBCD TusB component, DsrH family	96
2904405788	109	98.2	1	109	3	111	1.9e-41	135.1	COG2920	Sulfur relay (sulfurtransferase) protein, DsrC/TusE family	111
2904405789	300	96.86	145	291	3	156	2.7e-35	62.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2904405789	300	97.48	1	144	4	158	2.7e-35	59.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2904405790	670	33.48	562	664	147	221	9.7e-26	38.3	COG0569	Trk K+ transport system, NAD-binding component	225
2904405790	670	57.14	413	545	3	130	9.7e-26	44.9	COG0569	Trk K+ transport system, NAD-binding component	225
2904405790	670	96.08	1	393	3	394	8.7e-120	394.3	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
2904405791	219	89.71	85	219	12	133	1.2e-15	51.9	COG4520	Surface antigen	136
2904405792	557	100	2	557	1	554	0.0e+00	876.9	COG2759	Formyltetrahydrofolate synthetase	554
2904405793	78	12.47	1	70	83	131	2.3e-09	30.8	COG5659	SRSO17 transposase	385
2904405794	374	96.09	5	374	4	372	1.1e-102	338	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
2904405795	429	84.85	1	425	51	414	9.5e-07	21.3	COG3307	O-antigen ligase	424
2904405797	263	47.63	1	258	9	179	1.1e-20	68.6	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2904405798	385	97.31	4	377	7	404	1.6e-32	107.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904405799	378	98.29	1	372	2	403	1.1e-43	144.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904405800	556	96.3	210	526	8	345	4.4e-31	102.4	COG0673	Predicted dehydrogenase	342
2904405802	730	8.22	1	126	58	86	2.1e-39	14.9	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2904405802	730	62.61	120	369	124	344	2.1e-39	112.5	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2904405802	730	81.2	389	711	3	287	3.7e-52	172.4	COG0673	Predicted dehydrogenase	342
2904405804	431	85.06	13	431	5	414	2.3e-32	106.3	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2904405806	251	96.44	1	246	8	251	7.4e-82	268.5	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
2904405808	536	95.71	1	309	8	319	2.2e-73	241.7	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2904405809	129	95.93	8	129	4	121	2.4e-43	141.2	COG0818	Diacylglycerol kinase	123
2904405810	347	12.99	220	296	299	351	1.9e-25	26.4	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
2904405810	347	59.07	1	212	3	243	1.9e-25	56.1	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
2904405811	174	58.19	5	173	75	209	3.9e-25	83.6	COG0671	Membrane-associated phospholipid phosphatase	232
2904405812	346	97.56	1	333	3	401	1.6e-37	124.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904405813	269	98.76	8	246	1	238	2.1e-63	208.2	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
2904405814	258	65.52	12	246	15	185	4.2e-29	96	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2904405815	263	87.71	2	254	31	287	1.1e-54	179.8	COG3176	Putative hemolysin	292
2904405820	363	31.68	220	336	179	261	4.0e-62	63	COG3483	Tryptophan 2,3-dioxygenase (vermilion)	262
2904405820	363	60.31	6	224	2	159	4.0e-62	139.9	COG3483	Tryptophan 2,3-dioxygenase (vermilion)	262
2904405821	651	99.64	80	633	1	550	0.0e+00	519.2	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2904405823	311	30.99	37	129	5	79	1.9e-10	4.3	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
2904405823	311	47.93	135	307	91	206	1.9e-10	29	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
2904405824	214	97.21	3	214	2	210	6.6e-50	164.3	COG0625	Glutathione S-transferase	211
2904405825	325	95.97	4	325	9	270	9.7e-53	173.8	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2904405826	372	70.73	4	372	118	419	1.2e-92	304.6	COG3508	Homogentisate 1,2-dioxygenase	427
2904405827	351	94.77	1	351	15	358	0.0e+00	508.1	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
2904405828	62	65.08	2	62	23	63	4.8e-15	48.8	COG4256	Hemin uptake protein HemP	63
2904405829	253	84.67	24	252	41	272	2.3e-28	94.1	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2904405830	248	94.91	12	227	4	208	2.5e-53	175.5	COG0811	Biopolymer transport protein ExbB/TolQ	216
2904405831	142	92.09	1	140	10	137	3.4e-39	128.4	COG0848	Biopolymer transport protein ExbD	137
2904405832	715	93.73	2	715	40	742	4.4e-130	429.2	COG4774	Outer membrane receptor for monomeric catechols	750
2904405833	211	85.45	4	211	22	203	1.1e-34	114.1	COG3295	Uncharacterized protein	213
2904405837	655	97.34	1	631	4	662	6.3e-72	235.2	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2904405838	275	64.39	117	265	37	121	9.4e-17	54.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904405840	162	95.65	9	162	2	155	2.0e-47	154.9	COG3837	Uncharacterized conserved protein, cupin superfamily	161
2904405841	155	59.26	2	140	58	153	1.8e-07	26	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904405842	355	99.17	4	355	2	359	2.3e-103	340.1	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2904405844	308	97.01	6	302	2	293	5.5e-62	204.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904405845	765	88.82	9	336	17	310	0.0e+00	52	COG0620	Methionine synthase II (cobalamin-independent)	330
2904405845	765	99.4	423	754	2	330	0.0e+00	445.3	COG0620	Methionine synthase II (cobalamin-independent)	330
2904405847	128	74.14	4	128	19	104	4.1e-24	79	COG3339	Uncharacterized membrane protein YkvA, DUF1232 family	116
2904405849	548	92.88	52	480	4	277	2.5e-23	71.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904405850	136	93.53	1	136	7	136	3.0e-38	125.4	COG0848	Biopolymer transport protein ExbD	137
2904405851	229	93.52	3	214	7	208	3.2e-55	181.6	COG0811	Biopolymer transport protein ExbB/TolQ	216
2904405852	249	71.53	31	249	77	272	3.2e-38	126.5	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2904405855	156	17.42	4	72	37	67	1.7e-06	2.7	COG1633	Rubrerythrin	176
2904405855	156	30.34	74	146	15	68	1.7e-06	18.2	COG1633	Rubrerythrin	176
2904405856	369	15.08	268	367	410	482	1.8e-20	41.6	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904405856	369	23.97	65	295	64	179	1.8e-20	29	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904405857	302	94.03	1	302	17	268	1.5e-88	290.9	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2904405858	550	96.08	19	474	2	418	0.0e+00	664.6	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
2904405859	798	94.43	441	769	11	298	4.9e-81	265.8	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
2904405860	161	64.13	1	128	59	176	3.3e-25	82.8	COG3216	Uncharacterized conserved protein, DUF2062 family	184
2904405861	240	97.79	5	231	2	222	3.1e-85	279.3	COG1136	ABC-type lipoprotein export system, ATPase component	226
2904405862	415	100	1	415	1	410	0.0e+00	487.7	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2904405863	143	91.72	2	142	10	142	1.8e-49	161.6	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2904405864	150	65.33	2	138	13	110	3.7e-31	102.4	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
2904405865	89	88.89	1	89	4	91	4.8e-34	111.1	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
2904405866	450	97.52	2	450	6	438	0.0e+00	454.2	COG0733	Na+-dependent transporter, SNF family	439
2904405867	189	95.42	35	189	5	150	1.4e-67	220.3	COG0691	tmRNA-binding protein	153
2904405868	417	71.25	6	404	21	300	2.8e-101	333.4	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2904405869	331	86.39	1	324	42	352	1.7e-81	268.3	COG0628	Predicted PurR-regulated permease PerM	355
2904405870	148	78.91	3	111	27	127	3.9e-17	56.8	COG3794	Plastocyanin	128
2904405871	221	95.87	1	212	8	216	4.1e-33	109.1	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2904405872	132	90.98	2	132	6	126	1.8e-38	126.1	COG2346	Truncated hemoglobin YjbI	133
2904405873	279	13.95	12	43	2	25	8.8e-09	14.9	COG0703	Shikimate kinase	172
2904405873	279	34.3	133	226	79	137	8.8e-09	12.3	COG0703	Shikimate kinase	172
2904405874	356	18.57	269	345	247	303	7.9e-67	18.1	COG1897	Homoserine trans-succinylase	307
2904405874	356	83.06	1	277	1	255	7.9e-67	200.5	COG1897	Homoserine trans-succinylase	307
2904405875	78	31.25	45	78	29	53	1.9e-18	28.4	COG3369	Uncharacterized protein, contains Zn-finger domain of CDGSH type	78
2904405875	78	33.75	5	55	31	57	1.9e-18	37.4	COG3369	Uncharacterized protein, contains Zn-finger domain of CDGSH type	78
2904405876	386	98.38	2	377	3	367	0.0e+00	527.2	COG0505	Carbamoylphosphate synthase small subunit	368
2904405877	1074	96.59	564	956	1	396	0.0e+00	288.8	COG0458	Carbamoylphosphate synthase large subunit	400
2904405877	1074	97.32	13	424	1	399	0.0e+00	727.6	COG0458	Carbamoylphosphate synthase large subunit	400
2904405878	158	99.34	6	158	1	151	3.8e-61	199.9	COG0782	Transcription elongation factor, GreA/GreB family	151
2904405879	90	91.75	1	90	2	90	1.6e-30	99.5	COG1534	RNA-binding protein YhbY	97
2904405880	206	98.05	4	206	2	202	1.9e-83	273.5	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
2904405881	380	97.22	8	364	5	354	9.7e-81	265.7	COG0628	Predicted PurR-regulated permease PerM	355
2904405882	973	6.68	68	154	29	79	0.0e+00	13.4	COG0209	Ribonucleotide reductase alpha subunit	696
2904405882	973	97.12	205	973	13	753	0.0e+00	628.2	COG0209	Ribonucleotide reductase alpha subunit	696
2904405884	348	85.81	66	347	17	276	2.0e-43	142.5	COG0863	DNA modification methylase	302
2904405886	428	92.07	8	428	33	450	1.9e-122	403.3	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
2904405888	150	35.9	9	144	44	141	6.5e-04	13.2	COG0207	Thymidylate synthase	268
2904405891	420	95.61	78	420	13	339	1.0e-95	314.8	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
2904405892	501	95.89	8	500	18	437	1.4e-68	225.8	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
2904405895	651	52.68	57	216	35	142	3.2e-09	29.1	COG3642	tRNA A-37 threonylcarbamoyl transferase component Bud32	204
2904405897	108	39.59	4	101	120	197	1.4e-18	62.1	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2904405899	334	95.17	1	331	13	327	1.6e-36	120	COG0530	Ca2+/Na+ antiporter	320
2904405900	461	81.98	98	459	62	384	1.2e-57	190.2	COG0642	Signal transduction histidine kinase	336
2904405901	223	99.57	1	221	1	231	3.8e-75	246.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904405902	439	83.9	1	363	35	378	1.2e-48	159.9	COG4645	Uncharacterized protein	410
2904405903	215	93.75	1	200	2	196	3.4e-64	210.7	COG0288	Carbonic anhydrase	207
2904405904	463	98.42	1	460	4	439	0.0e+00	480.8	COG1030	Membrane-bound serine protease (ClpP class)	436
2904405905	253	13.29	197	243	245	284	6.6e-62	4.2	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2904405905	253	72.76	1	215	6	224	6.6e-62	203	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2904405907	207	41.18	6	207	74	241	6.2e-35	114.5	COG3748	Uncharacterized membrane protein	407
2904405908	703	47.87	11	158	29	129	1.6e-10	34.4	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2904405908	703	64.71	206	697	214	642	2.5e-113	373.4	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2904405910	170	93.17	10	165	10	159	2.5e-49	161.9	COG1267	Phosphatidylglycerophosphatase A	160
2904405911	320	100	1	317	1	320	8.9e-109	357.6	COG0611	Thiamine monophosphate kinase	317
2904405912	198	92.16	1	191	11	151	1.9e-37	121.6	COG0781	Transcription termination factor NusB	151
2904405913	159	99.34	4	155	2	152	4.0e-62	202.8	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
2904405914	367	86.73	202	367	2	171	7.9e-44	143.6	COG0807	GTP cyclohydrolase II	193
2904405914	367	98.03	1	202	4	202	4.1e-85	278.4	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
2904405915	218	96.59	1	205	1	198	1.6e-75	246.9	COG0307	Riboflavin synthase alpha chain	204
2904405916	370	97.26	6	151	4	145	1.8e-60	196.8	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
2904405916	370	97.73	152	370	2	216	1.7e-65	214.7	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
2904405917	169	97.44	1	156	1	152	6.7e-67	218.5	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
2904405918	418	98.55	2	417	6	414	0.0e+00	660.1	COG0112	Glycine/serine hydroxymethyltransferase	413
2904405919	331	85.51	1	69	4	62	3.9e-20	64.9	COG1983	Phage shock protein PspC (stress-responsive transcriptional regulator)	70
2904405920	443	74.46	108	429	93	366	8.9e-44	144	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2904405921	371	96.68	7	356	8	269	6.1e-78	256.4	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2904405924	405	96.11	2	390	14	384	7.4e-73	240	COG3853	Uncharacterized conserved protein YaaN involved in tellurite resistance	386
2904405925	456	83.25	76	453	56	383	1.6e-44	147.3	COG0642	Signal transduction histidine kinase	336
2904405926	227	98.71	1	224	1	229	3.1e-80	263.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904405929	930	62.21	3	489	6	382	3.4e-47	154.7	COG0443	Molecular chaperone DnaK (HSP70)	579
2904405933	313	62.35	7	311	64	222	1.6e-08	25.1	COG1462	Curli biogenesis system outer membrane secretion channel CsgG	252
2904405934	369	99.71	10	350	2	341	0.0e+00	481.3	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
2904405935	495	11.46	55	153	35	67	3.2e-86	2.2	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
2904405935	495	98.26	213	495	4	286	3.2e-86	283.4	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
2904405936	151	95.97	1	148	2	144	1.2e-47	155.7	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
2904405937	443	91.35	21	413	22	264	6.1e-76	249.3	COG0860	N-acetylmuramoyl-L-alanine amidase	231
2904405939	595	34.42	348	594	423	644	0.0e+00	176.8	COG0323	DNA mismatch repair ATPase MutL	638
2904405939	595	52.56	1	384	1	339	0.0e+00	485.3	COG0323	DNA mismatch repair ATPase MutL	638
2904405940	312	94.16	3	310	3	292	6.2e-119	390.8	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
2904405941	373	98.13	1	371	6	373	0.0e+00	607.8	COG5008	Tfp pilus assembly protein, ATPase PilU	375
2904405942	344	96.88	1	344	3	344	0.0e+00	539.5	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
2904405943	241	98.69	3	227	2	227	7.2e-86	281.8	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
2904405944	274	99.63	3	271	2	268	8.0e-90	295.2	COG0345	Pyrroline-5-carboxylate reductase	266
2904405945	191	83.33	5	97	11	90	3.7e-33	50.2	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
2904405945	191	85.42	94	189	6	87	3.7e-33	64	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
2904405946	99	79.41	1	95	7	87	2.9e-28	92.2	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
2904405948	205	89.43	1	203	23	225	1.3e-74	244.9	COG0220	tRNA G46 methylase TrmB	227
2904405952	149	86.14	1	147	22	164	9.7e-47	152.8	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2904405953	516	98.35	93	515	3	419	0.0e+00	548.9	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2904405954	948	22.09	14	235	3	218	0.0e+00	281.8	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2904405954	948	71.37	232	946	263	960	0.0e+00	980.2	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2904405955	276	95.88	11	273	10	265	5.6e-82	269.2	COG1526	Formate dehydrogenase assembly factor FdhD	266
2904405957	364	96.39	1	363	4	377	3.0e-70	231.7	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2904405959	891	92.18	5	885	6	842	0.0e+00	597.1	COG1615	Uncharacterized membrane protein, UPF0182 family	885
2904405960	308	92.96	20	214	14	198	4.3e-52	171.8	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2904405961	134	48.17	8	130	65	143	1.9e-08	29.1	COG2010	Cytochrome c, mono- and diheme variants	150
2904405964	171	95.74	25	166	3	137	1.9e-60	196.8	COG0229	Peptide methionine sulfoxide reductase MsrB	140
2904405965	779	97.85	90	779	8	691	0.0e+00	923.3	COG0855	Polyphosphate kinase	696
2904405966	501	98.38	8	490	3	489	0.0e+00	487.4	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
2904405967	312	99.35	1	302	2	305	8.7e-90	295.6	COG1131	ABC-type multidrug transport system, ATPase component	293
2904405968	254	91.81	3	253	23	291	1.1e-19	65	COG0842	ABC-type multidrug transport system, permease component	286
2904405969	272	90.85	2	272	19	276	2.5e-91	299.9	COG3770	Murein endopeptidase	284
2904405970	360	34.32	83	326	62	165	1.5e-02	7.1	COG1234	Ribonuclease BN, tRNA processing enzyme	292
2904405972	47	31.97	1	43	7	45	7.7e-04	13.8	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
2904405975	339	98.44	1	328	1	315	1.9e-100	330.2	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2904405977	926	98.17	1	912	12	871	0.0e+00	564.4	COG4096	Type I site-specific restriction endonuclease, part of a restriction-modification system	875
2904405978	512	80.25	25	474	70	394	2.2e-34	111.7	COG0732	Restriction endonuclease S subunit	391
2904405979	500	97.23	9	482	5	461	3.8e-61	200.8	COG2865	Predicted transcriptional regulator, contains HTH domain	467
2904405980	483	85.09	1	468	6	450	1.2e-82	272.5	COG0286	Type I restriction-modification system, DNA methylase subunit	489
2904405981	316	95.64	9	309	2	308	5.0e-72	236.6	COG3458	Cephalosporin-C deacetylase or related acetyl esterase	321
2904405982	51	96.08	1	49	3	51	1.2e-27	90.4	COG0267	Ribosomal protein L33	50
2904405983	78	98.7	1	76	1	76	1.9e-35	115.3	COG0227	Ribosomal protein L28	77
2904405984	316	99.37	3	316	1	313	2.3e-91	300.3	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2904405985	283	78.83	7	276	57	272	7.5e-33	108.9	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2904405988	180	92.55	1	180	10	183	6.7e-46	150.7	COG2229	Signal recognition particle receptor subunit beta, a GTPase	187
2904405990	120	98.32	2	120	3	119	7.0e-39	126.9	COG2018	Predicted regulator of Ras-like GTPase activity, Roadblock/LC7/MglB family	119
2904405991	157	46.69	6	148	130	242	4.4e-17	56.7	COG2202	PAS domain	232
2904405992	248	30.23	7	115	55	145	1.6e-06	10.5	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
2904405992	248	33.22	117	246	192	291	1.6e-06	9.9	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
2904405993	188	95.36	1	188	9	193	2.6e-71	233.4	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
2904405994	157	96.45	13	153	3	138	2.4e-36	119.1	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
2904405995	172	82.12	4	168	17	163	7.7e-47	153.3	COG2065	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	179
2904405996	331	97.46	11	322	5	311	1.8e-116	382.7	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
2904405997	426	97.45	3	426	3	422	6.1e-126	415	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2904405998	170	85.79	2	170	27	183	1.2e-51	169.6	COG2032	Cu/Zn superoxide dismutase	179
2904406000	219	97.31	1	219	1	217	1.3e-93	307.2	COG2884	ABC-type ATPase involved in cell division	223
2904406001	329	97.98	28	329	5	295	4.6e-74	243.4	COG2177	Cell division protein FtsX	297
2904406002	284	77.42	2	283	66	329	7.1e-83	273.1	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2904406003	188	48.54	5	152	48	163	9.4e-29	94.3	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2904406005	362	33.21	226	335	174	260	9.1e-45	36.3	COG3483	Tryptophan 2,3-dioxygenase (vermilion)	262
2904406005	362	59.92	5	198	2	158	9.1e-45	109.8	COG3483	Tryptophan 2,3-dioxygenase (vermilion)	262
2904406007	530	90.16	322	530	17	181	1.5e-51	168.2	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904406008	487	99.38	1	487	1	480	0.0e+00	726.6	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
2904406009	788	90.26	7	787	71	839	0.0e+00	493.5	COG3264	Small-conductance mechanosensitive channel	835
2904406010	277	98.07	1	258	1	254	6.9e-90	295.2	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2904406011	241	96.37	3	240	3	241	5.5e-86	282.4	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
2904406012	252	90.31	1	190	7	183	3.8e-81	265.3	COG1045	Serine acetyltransferase	194
2904406013	416	91.65	17	413	3	375	2.3e-104	343.9	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
2904406014	271	89.51	5	270	33	305	3.9e-60	198.1	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2904406016	307	97.01	1	296	6	297	2.5e-85	280.7	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2904406017	146	97.87	3	145	3	140	1.1e-43	143.3	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
2904406018	662	87.87	170	539	28	324	1.8e-38	126.8	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2904406019	317	71.22	36	317	5	301	4.8e-34	112.3	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2904406020	304	89.09	1	303	12	305	1.1e-84	278.7	COG0714	MoxR-like ATPase	329
2904406021	873	64.1	384	870	219	643	2.8e-122	403	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2904406022	152	91.25	3	152	6	151	5.9e-26	85.8	COG0680	Ni,Fe-hydrogenase maturation factor	160
2904406023	504	22.48	2	144	5	131	1.2e-110	122.2	COG0374	Ni,Fe-hydrogenase I large subunit	545
2904406023	504	64.42	137	502	194	557	1.2e-110	240.6	COG0374	Ni,Fe-hydrogenase I large subunit	545
2904406024	313	74.93	1	309	49	314	1.3e-72	238.8	COG1740	Ni,Fe-hydrogenase I small subunit	355
2904406025	643	99.2	22	643	3	621	0.0e+00	961.8	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
2904406026	206	95.81	5	205	5	210	7.8e-57	186.2	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
2904406027	264	97.73	1	257	1	258	9.1e-85	278.9	COG1192	Cellulose biosynthesis protein BcsQ	259
2904406028	281	98.11	25	276	4	262	5.3e-72	237.2	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2904406029	125	85.94	4	124	13	122	8.6e-24	78.3	COG3312	FoF1-type ATP synthase assembly protein I	128
2904406030	259	96.43	4	259	10	252	9.8e-83	271.6	COG0356	FoF1-type ATP synthase, membrane subunit a	246
2904406031	87	93.75	1	80	6	80	1.9e-21	70.3	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
2904406032	159	97.52	1	159	4	160	1.1e-47	156	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2904406033	178	99.44	1	177	1	177	3.0e-51	168.1	COG0712	FoF1-type ATP synthase, delta subunit	178
2904406034	513	99.4	1	513	1	501	0.0e+00	801.4	COG0056	FoF1-type ATP synthase, alpha subunit	504
2904406035	287	99.65	5	287	1	287	7.9e-114	374.5	COG0224	FoF1-type ATP synthase, gamma subunit	287
2904406036	460	99.15	1	460	1	464	0.0e+00	814.5	COG0055	FoF1-type ATP synthase, beta subunit	468
2904406037	140	99.26	1	135	1	134	2.7e-44	144.6	COG0355	FoF1-type ATP synthase, epsilon subunit	135
2904406038	456	99.13	1	456	3	457	0.0e+00	628.8	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
2904406039	610	100	1	610	1	615	0.0e+00	801.8	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
2904406042	136	67.24	5	106	28	105	1.7e-25	83.4	COG3339	Uncharacterized membrane protein YkvA, DUF1232 family	116
2904406043	270	49.69	2	270	31	271	5.2e-47	155.1	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2904406044	326	97.34	2	321	5	297	2.2e-51	169	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2904406045	324	95.35	17	319	9	295	1.8e-63	208.9	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2904406048	222	95.54	7	205	10	202	1.2e-47	156.5	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
2904406051	128	96.18	1	128	4	129	4.0e-50	163.3	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
2904406052	453	96.23	1	451	12	445	0.0e+00	446	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
2904406053	482	94.77	1	482	9	479	0.0e+00	616.7	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2904406054	120	91.87	3	120	6	118	1.6e-42	138.4	COG0818	Diacylglycerol kinase	123
2904406055	314	95.57	2	305	4	305	5.4e-41	134.9	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2904406056	264	51.84	1	263	234	486	2.3e-77	255.4	COG3956	Uncharacterized conserved protein YabN, contains tetrapyrrole methylase and MazG-like pyrophosphatase domain	488
2904406057	220	98.12	8	220	2	210	2.5e-76	250.3	COG1515	Deoxyinosine 3'endonuclease (endonuclease V)	212
2904406061	184	90.22	9	183	5	170	5.5e-36	118.6	COG4970	Tfp pilus assembly protein FimT	181
2904406062	186	73.94	1	164	14	135	9.7e-20	65.2	COG4967	Tfp pilus assembly protein PilV	162
2904406063	346	21.17	1	341	11	79	9.1e-24	75.4	COG4966	Tfp pilus assembly protein PilW	318
2904406064	171	72.44	14	138	15	127	1.4e-04	16.6	COG2165	Type II secretory pathway, pseudopilin PulG	149
2904406066	145	98.56	5	145	3	139	3.1e-38	125.7	COG4968	Tfp pilus assembly protein PilE	139
2904406067	150	98.56	3	149	3	139	5.6e-37	121.5	COG4968	Tfp pilus assembly protein PilE	139
2904406068	1340	43.73	829	1340	552	1011	0.0e+00	429.4	COG3419	Tfp pilus assembly protein, tip-associated adhesin PilY1	1036
2904406068	1340	45.91	285	823	76	558	0.0e+00	89.6	COG3419	Tfp pilus assembly protein, tip-associated adhesin PilY1	1036
2904406069	177	23.98	101	176	145	191	1.4e-30	35.4	COG4726	Tfp pilus assembly protein PilX	196
2904406069	177	32.65	5	80	8	71	1.4e-30	67.5	COG4726	Tfp pilus assembly protein PilX	196
2904406070	365	94.48	7	365	9	316	2.4e-28	91.5	COG4966	Tfp pilus assembly protein PilW	318
2904406071	155	64.85	3	138	8	114	1.3e-20	68.2	COG4967	Tfp pilus assembly protein PilV	162
2904406072	166	68.48	1	165	12	137	2.7e-28	93.6	COG4970	Tfp pilus assembly protein FimT	181
2904406073	95	93.94	1	95	3	95	7.9e-47	151.7	COG3526	Predicted selenoprotein, Rdx family	99
2904406074	268	97.68	1	268	4	256	2.2e-58	191.5	COG0730	Uncharacterized membrane protein YfcA	258
2904406075	416	91.33	1	395	23	401	1.9e-89	295	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
2904406076	320	97.78	8	316	6	313	3.5e-78	257	COG1665	Predicted nucleotidyltransferase	315
2904406078	228	97.29	12	228	2	216	1.6e-47	156.6	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2904406081	91	57.76	7	91	48	114	4.1e-30	98.5	COG3450	Predicted enzyme of the cupin superfamily	116
2904406082	123	55.73	5	110	30	102	7.5e-06	20.1	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2904406084	477	98.11	33	476	5	420	2.3e-67	221.1	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
2904406085	221	96.79	9	216	4	214	3.6e-41	135.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2904406086	83	22.22	2	67	45	70	2.5e-04	15.4	COG3462	Uncharacterized membrane protein	117
2904406090	1115	51.36	379	611	106	294	2.0e-19	40.9	COG0457	Tetratricopeptide (TPR) repeat	291
2904406090	1115	57.61	128	414	132	343	2.0e-19	37.2	COG0457	Tetratricopeptide (TPR) repeat	291
2904406091	748	36.7	7	211	49	197	1.1e-29	46.6	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2904406091	748	37.93	275	450	242	395	1.1e-29	53.1	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2904406091	748	72.54	483	672	59	235	8.7e-36	116.9	COG2114	Adenylate cyclase, class 3	227
2904406096	624	99.54	136	592	2	433	0.0e+00	741.7	COG0422	Thiamine biosynthesis protein ThiC	432
2904406098	562	97.85	7	524	4	504	0.0e+00	481	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
2904406099	92	98.86	1	88	1	87	1.3e-33	109	COG0851	Septum formation topological specificity factor MinE	88
2904406100	269	98.16	1	269	2	268	2.6e-129	424.4	COG2894	Septum formation inhibitor-activating ATPase MinD	272
2904406101	245	97.82	14	245	3	226	1.8e-60	199.1	COG0850	Septum formation inhibitor MinC	219
2904406102	290	97.19	1	289	1	311	9.0e-68	218.6	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2904406103	136	44.85	1	136	8	142	1.8e-14	48.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2904406105	268	90.44	8	251	16	242	5.4e-75	245.9	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
2904406106	216	72.83	7	213	3	187	5.4e-16	52.3	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2904406107	111	97.14	1	103	3	104	8.3e-46	148.4	COG0278	Glutaredoxin-related protein	105
2904406108	339	98.28	1	339	4	345	1.6e-126	416.3	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2904406110	485	97.08	3	485	5	503	4.4e-106	349.7	COG0168	Trk-type K+ transport system, membrane component	499
2904406111	475	98.11	32	473	5	420	2.6e-58	191.1	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
2904406112	234	98.71	6	234	3	231	2.5e-76	250.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904406113	527	54.52	3	521	404	892	0.0e+00	433.2	COG2205	K+-sensing histidine kinase KdpD	890
2904406114	528	92.34	5	527	36	529	0.0e+00	623.7	COG3131	Periplasmic glucans biosynthesis protein	534
2904406117	301	99.32	12	294	1	293	1.0e-52	173.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904406118	210	54.23	53	207	90	230	2.8e-12	41.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2904406120	171	96.94	1	171	3	192	2.9e-53	175	COG0693	Putative intracellular protease/amidase	188
2904406121	65	24.52	1	58	57	107	1.8e-03	12.3	COG3166	Tfp pilus assembly protein PilN	206
2904406122	218	96.36	2	218	3	214	1.7e-90	296.6	COG1926	Predicted phosphoribosyltransferase	220
2904406123	221	20.34	146	219	233	292	2.9e-14	18.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904406123	221	38.64	5	156	23	136	2.9e-14	29.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904406124	327	98.43	1	326	5	317	8.2e-87	285.6	COG0462	Phosphoribosylpyrophosphate synthetase	314
2904406127	231	76.87	1	227	7	212	9.8e-40	131.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904406128	209	89.74	82	209	7	146	2.4e-04	11.9	COG0328	Ribonuclease HI	154
2904406132	133	91.78	1	133	10	143	1.1e-30	100.4	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2904406133	803	58.26	283	428	100	240	7.3e-62	79.5	COG2202	PAS domain	232
2904406133	803	58.26	418	553	102	242	7.3e-62	67.5	COG2202	PAS domain	232
2904406133	803	73.97	18	301	64	242	7.3e-62	78.9	COG2202	PAS domain	232
2904406135	145	69.93	1	138	9	115	2.0e-32	106.6	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2904406138	273	98.17	31	270	3	217	6.8e-59	193	COG1878	Kynurenine formamidase	218
2904406139	523	97.91	27	503	9	477	0.0e+00	461.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2904406141	362	95.36	1	362	1	370	3.7e-68	224.6	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
2904406142	566	95.74	5	544	17	555	0.0e+00	440.5	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2904406143	224	95.67	1	206	4	202	3.4e-55	181.3	COG0288	Carbonic anhydrase	207
2904406144	969	97.65	8	527	10	467	1.1e-94	311.4	COG0277	FAD/FMN-containing dehydrogenase	459
2904406144	969	97.76	553	969	8	399	2.0e-49	161.1	COG0247	Fe-S oxidoreductase	388
2904406145	266	98.88	7	264	3	267	2.2e-54	179.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904406146	482	98.96	4	481	2	475	0.0e+00	558.5	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2904406147	139	94.12	1	139	7	134	1.2e-27	90.7	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2904406148	170	60.47	2	124	44	121	3.6e-07	24.1	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2904406149	132	81.4	1	113	16	120	2.8e-45	147.6	COG2852	Very-short-patch-repair endonuclease	129
2904406150	336	80.92	4	333	56	301	2.0e-27	90.7	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2904406151	272	76.26	15	222	4	170	4.0e-07	22.2	COG1878	Kynurenine formamidase	218
2904406152	423	97.3	1	423	7	402	2.8e-118	389.3	COG3844	Kynureninase	407
2904406153	455	87.79	2	418	7	351	5.9e-45	148.4	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2904406154	512	7.67	402	447	211	238	2.4e-20	14.7	COG1858	Cytochrome c peroxidase	364
2904406154	512	9.59	437	512	294	328	2.4e-20	22.4	COG1858	Cytochrome c peroxidase	364
2904406154	512	41.37	187	408	155	305	2.4e-20	27.5	COG1858	Cytochrome c peroxidase	364
2904406155	305	96.32	3	299	5	292	5.6e-55	180	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2904406156	123	83.94	1	123	6	120	5.0e-11	37.4	COG3011	Predicted thiol-disulfide oxidoreductase YuxK, DCC family	137
2904406157	393	27.3	39	217	87	196	1.1e-09	29.2	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904406157	393	34.49	158	355	43	181	1.1e-09	4.3	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904406158	674	81.88	195	674	78	425	4.0e-98	323.9	COG0840	Methyl-accepting chemotaxis protein	408
2904406160	441	16.46	1	103	11	77	5.5e-51	61.2	COG1228	Imidazolonepropionase or related amidohydrolase	406
2904406160	441	45.95	153	430	217	403	5.5e-51	108.8	COG1228	Imidazolonepropionase or related amidohydrolase	406
2904406161	211	95.11	5	201	1	175	3.0e-40	132.1	COG0431	NAD(P)H-dependent FMN reductase	184
2904406163	194	66.67	1	187	6	179	7.3e-64	209.8	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
2904406164	158	89.82	1	156	11	160	5.6e-50	163.2	COG0597	Lipoprotein signal peptidase	167
2904406165	939	99.79	3	933	1	945	0.0e+00	1170.4	COG0060	Isoleucyl-tRNA synthetase	933
2904406166	318	99.67	1	308	1	306	2.5e-113	372.5	COG0196	FAD synthase	304
2904406167	504	96.33	1	501	17	515	0.0e+00	586.1	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
2904406168	92	98.86	1	88	1	87	4.1e-34	111.3	COG0268	Ribosomal protein S20	88
2904406169	374	99.19	5	374	3	369	0.0e+00	435.5	COG0263	Glutamate 5-kinase	369
2904406170	344	92.56	1	344	1	336	0.0e+00	476.2	COG0536	GTPase involved in cell partioning and DNA repair	369
2904406171	87	96.55	1	87	1	84	1.3e-44	144.3	COG0211	Ribosomal protein L27	87
2904406172	103	99.03	1	103	1	102	3.0e-44	144.1	COG0261	Ribosomal protein L21	103
2904406173	270	79.85	1	224	2	211	1.8e-52	172.2	COG2218	Formylmethanofuran dehydrogenase subunit C	264
2904406174	298	100	1	297	1	297	4.5e-106	348.8	COG2037	Formylmethanofuran:tetrahydromethanopterin formyltransferase	297
2904406175	556	97.57	1	550	6	566	0.0e+00	522.9	COG1229	Formylmethanofuran dehydrogenase subunit A	575
2904406176	427	98.37	8	426	3	424	5.6e-47	154.4	COG1029	Formylmethanofuran dehydrogenase subunit B	429
2904406185	771	3.85	254	360	683	724	8.6e-01	1.1	COG4733	Phage-related protein, tail component	952
2904406185	771	4.4	425	522	665	712	8.6e-01	2.2	COG4733	Phage-related protein, tail component	952
2904406185	771	5.23	167	304	677	733	8.6e-01	1.6	COG4733	Phage-related protein, tail component	952
2904406185	771	6.06	25	208	662	727	8.6e-01	2.2	COG4733	Phage-related protein, tail component	952
2904406185	771	6.24	354	453	669	736	8.6e-01	6.4	COG4733	Phage-related protein, tail component	952
2904406190	337	99.04	12	324	3	311	1.9e-82	271.1	COG1907	Predicted archaeal sugar kinase	312
2904406191	371	91.28	2	369	12	367	2.2e-31	103.2	COG2232	Predicted ATP-dependent carboligase, ATP-grasp superfamily	389
2904406192	331	99.68	5	331	1	313	9.2e-96	315	COG3252	Methenyltetrahydromethanopterin cyclohydrolase	314
2904406193	304	72.7	52	289	78	306	8.5e-40	130.6	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2904406194	295	93.45	7	283	18	288	1.2e-26	87.8	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
2904406195	170	95.88	5	170	3	165	1.4e-61	201.7	COG1795	Formaldehyde-activating enzyme nesessary for methanogenesis	170
2904406196	239	96.52	1	233	1	222	3.5e-37	122.1	COG1411	Uncharacterized protein related to proFAR isomerase (HisA)	229
2904406197	332	90.23	1	321	1	277	1.1e-38	127.3	COG1821	Predicted ATP-dependent carboligase, ATP-grasp superfamily	307
2904406198	352	99.09	1	348	1	327	2.0e-59	195.7	COG1548	Uncharacterized protein, hydantoinase/oxoprolinase family	330
2904406199	468	96.36	4	461	15	464	0.0e+00	501.3	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2904406200	206	70.75	4	166	3	152	1.2e-29	97.6	COG2054	Uncharacterized archaeal kinase related to aspartokinase	212
2904406201	77	98.81	2	77	2	84	3.3e-19	63.5	COG1977	Molybdopterin converting factor, small subunit	84
2904406202	146	83.22	3	145	18	141	3.6e-46	150.8	COG0314	Molybdopterin synthase catalytic subunit	149
2904406203	174	53.02	16	168	100	213	6.3e-34	112.1	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
2904406204	203	94.12	9	202	10	201	5.6e-41	134.3	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
2904406205	544	45.97	434	543	37	93	1.6e-29	29.1	COG1145	Ferredoxin	99
2904406205	544	76.61	141	451	19	113	1.6e-29	62.7	COG1145	Ferredoxin	99
2904406208	81	90.48	1	80	1	76	7.8e-22	71.6	COG4118	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor	84
2904406209	125	94.62	1	124	4	126	1.8e-38	125.6	COG3744	PIN domain nuclease, a component of toxin-antitoxin system (PIN domain)	130
2904406210	325	93.69	2	322	16	297	1.3e-47	156.6	COG3440	Predicted restriction endonuclease	301
2904406211	127	81.56	3	124	2	116	4.5e-36	118.1	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2904406213	126	94.87	7	123	4	114	3.7e-29	95.1	COG2361	Uncharacterized conserved protein, contains HEPN domain	117
2904406214	103	89.69	1	94	9	95	6.3e-27	87.8	COG1669	Predicted nucleotidyltransferase	97
2904406217	966	99.38	23	960	3	807	0.0e+00	619.9	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2904406218	96	97.85	1	91	2	92	1.3e-32	106.2	COG2929	Uncharacterized conserved protein, DUF497 family	93
2904406220	189	62	37	189	71	194	3.3e-16	53.5	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
2904406221	202	73.66	1	193	14	164	3.3e-45	147.9	COG0437	Fe-S-cluster-containing dehydrogenase component	203
2904406223	348	93.58	121	337	4	207	1.7e-51	169.3	COG2864	Cytochrome b subunit of formate dehydrogenase	218
2904406224	69	97.18	1	69	1	69	1.1e-32	106.8	COG3360	Flavin-binding protein dodecin	71
2904406225	180	90.17	1	163	11	166	1.5e-37	123.5	COG1495	Disulfide bond formation protein DsbB	170
2904406226	230	98.71	4	229	2	230	2.0e-87	286.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904406227	410	81.98	7	397	65	387	6.9e-64	210.9	COG0642	Signal transduction histidine kinase	336
2904406228	321	95.38	3	309	15	324	1.9e-26	87	COG0226	ABC-type phosphate transport system, periplasmic component	318
2904406229	343	69.85	163	343	58	196	3.0e-38	126.2	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2904406230	368	91.69	4	334	27	324	9.6e-45	147.3	COG0226	ABC-type phosphate transport system, periplasmic component	318
2904406231	125	82.27	1	122	22	137	3.6e-41	134.5	COG4446	Uncharacterized conserved protein, DUF1499 family	141
2904406232	276	96.43	4	275	9	278	1.0e-103	340.5	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
2904406233	462	99.36	10	461	2	467	2.4e-122	403.4	COG0277	FAD/FMN-containing dehydrogenase	459
2904406234	195	98.87	3	181	2	176	3.2e-67	220	COG0279	Phosphoheptose isomerase	176
2904406235	120	97.37	5	119	3	113	1.2e-35	116.2	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
2904406236	631	93.55	2	615	35	600	6.5e-102	332.7	COG3107	Outer membrane lipoprotein LpoA, binds and activates PBP1a	604
2904406237	289	98.16	4	282	4	270	1.7e-99	326.5	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
2904406240	396	99.49	3	393	1	391	2.3e-100	330.9	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2904406241	438	94.36	2	431	22	389	1.0e-107	353.8	COG0006	Xaa-Pro aminopeptidase	384
2904406242	178	92.47	1	177	7	178	1.3e-35	117	COG3079	Uncharacterized conserved protein YgfB, UPF0149 family	186
2904406243	70	9.05	3	70	416	474	4.5e-05	16.2	COG2433	Possible nuclease of RNase H fold, RuvC/YqgF family	652
2904406244	100	86.67	3	100	4	94	1.1e-26	87.4	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
2904406246	183	85.34	4	178	25	187	4.5e-44	144.9	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
2904406247	189	81.5	7	189	34	196	1.3e-17	58	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
2904406249	152	94.87	1	152	2	149	5.4e-68	222.1	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
2904406250	509	98.27	1	339	7	346	0.0e+00	432.9	COG1171	Threonine dehydratase	347
2904406251	218	98.68	1	218	1	225	2.4e-84	276.4	COG0120	Ribose 5-phosphate isomerase	227
2904406252	331	100	1	330	1	331	3.5e-96	316.7	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2904406253	189	47.79	28	162	131	249	5.5e-41	135.6	COG0791	Cell wall-associated hydrolase, NlpC family	197
2904406254	403	93.16	3	367	25	392	1.2e-76	251.9	COG0019	Diaminopimelate decarboxylase	394
2904406255	325	98.04	19	324	3	302	0.0e+00	459.8	COG0320	Lipoate synthase	306
2904406256	215	92.44	1	213	8	215	3.3e-79	259.6	COG0321	Lipoate-protein ligase B	221
2904406257	480	97.14	31	480	10	450	0.0e+00	486.8	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
2904406258	90	92.22	1	90	8	90	2.5e-26	86.3	COG2921	Putative lipoic acid-binding regulatory protein	90
2904406259	282	96.84	6	279	4	279	9.9e-68	223.1	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2904406260	381	96.44	1	381	11	389	6.4e-129	424.9	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2904406261	295	82.42	1	291	56	341	2.0e-101	333.9	COG2951	Membrane-bound lytic murein transglycosylase B	343
2904406262	378	95.03	13	377	13	375	2.7e-115	379.3	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
2904406263	614	97.94	6	614	5	623	0.0e+00	537.2	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2904406264	143	82.63	1	142	23	160	9.2e-31	101.3	COG2891	Cell shape-determining protein MreD	167
2904406265	222	70.28	1	216	73	273	5.5e-62	203.6	COG1792	Cell shape-determining protein MreC	284
2904406266	348	97.65	6	346	3	335	0.0e+00	501.3	COG1077	Actin-like ATPase involved in cell morphogenesis	342
2904406267	95	98.96	1	95	1	95	2.0e-26	86.6	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
2904406268	484	98.96	1	481	5	480	0.0e+00	621.9	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2904406269	477	98.96	1	477	4	481	0.0e+00	705.3	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
2904406270	1111	86.32	1	203	30	231	8.3e-35	114.5	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
2904406270	1111	95.03	198	1104	43	960	0.0e+00	884.9	COG0474	Magnesium-transporting ATPase (P-type)	917
2904406271	205	89.64	11	203	5	203	1.0e-30	100.7	COG2928	Uncharacterized membrane protein	222
2904406272	137	76.3	5	131	4	106	1.7e-19	64.6	COG1310	Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif	134
2904406273	299	98.61	13	294	2	284	7.0e-87	285.5	COG2890	Methylase of polypeptide chain release factors	280
2904406274	360	99.17	1	360	2	361	0.0e+00	542.6	COG0216	Protein chain release factor A	363
2904406275	420	99.76	1	418	1	413	0.0e+00	500.9	COG0373	Glutamyl-tRNA reductase	414
2904406276	574	77.72	25	350	50	335	8.9e-37	58.2	COG0457	Tetratricopeptide (TPR) repeat	291
2904406276	574	79.62	317	573	52	344	8.9e-37	64.8	COG0457	Tetratricopeptide (TPR) repeat	291
2904406277	195	95.15	1	194	10	205	1.8e-30	100.4	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
2904406278	283	98.28	4	279	4	288	6.2e-85	279.1	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
2904406280	317	98.74	1	316	4	317	2.1e-127	418.9	COG0462	Phosphoribosylpyrophosphate synthetase	314
2904406281	202	96.77	4	97	4	93	2.5e-28	92	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
2904406282	198	96.83	4	192	3	185	6.9e-69	225.3	COG0193	Peptidyl-tRNA hydrolase	190
2904406286	36	8.88	1	36	1	35	7.4e-19	61	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2904406289	124	7.94	6	103	515	582	1.7e-04	14.4	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904406291	246	89	8	223	17	202	8.1e-17	56.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904406292	339	76.42	1	297	20	288	1.6e-42	139.5	COG1566	Multidrug resistance efflux pump	352
2904406293	541	58.82	14	263	60	239	0.0e+00	173	COG1131	ABC-type multidrug transport system, ATPase component	293
2904406293	541	73.2	288	538	4	227	0.0e+00	260.7	COG1131	ABC-type multidrug transport system, ATPase component	293
2904406294	380	72.7	91	380	77	289	6.1e-28	92.3	COG0842	ABC-type multidrug transport system, permease component	286
2904406295	373	86.01	90	372	37	288	2.7e-30	99.7	COG0842	ABC-type multidrug transport system, permease component	286
2904406296	467	97.83	1	463	3	452	2.4e-103	340.8	COG1538	Outer membrane protein TolC	457
2904406297	102	95.96	1	99	1	95	1.5e-16	55.2	COG3668	Plasmid stabilization system protein ParE	98
2904406298	83	23.08	5	83	186	257	2.9e-03	11.1	COG1907	Predicted archaeal sugar kinase	312
2904406301	170	62.35	2	144	54	154	3.6e-09	31.5	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904406302	215	89.14	4	213	4	200	7.0e-44	144.5	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2904406303	295	95.68	1	285	9	296	1.5e-37	123.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2904406304	220	49.54	2	208	34	194	7.0e-20	65.4	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2904406305	197	93.05	1	183	7	180	5.3e-39	128.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2904406306	190	70.59	1	119	6	101	5.7e-10	33.5	COG1943	REP element-mobilizing transposase RayT	136
2904406307	81	22.18	1	63	208	270	2.1e-06	20.6	COG2801	Transposase InsO and inactivated derivatives	232
2904406316	97	91.58	1	93	8	94	2.0e-26	86	COG4453	Uncharacterized conserved protein, DUF1778 family	95
2904406317	169	65.43	16	160	50	155	1.5e-08	28.7	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904406318	126	93.16	1	120	6	114	6.8e-36	116.9	COG2361	Uncharacterized conserved protein, contains HEPN domain	117
2904406319	96	90.72	1	96	10	97	6.9e-24	78.3	COG1669	Predicted nucleotidyltransferase	97
2904406321	88	81.43	1	87	10	66	6.2e-14	42	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2904406323	407	82.66	1	404	50	440	1.3e-124	410.5	COG4623	Membrane-bound lytic murein transglycosylase MltF	473
2904406324	150	95.42	1	148	7	152	1.7e-54	178.4	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2904406325	525	98.99	7	206	2	197	1.1e-72	237.7	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2904406325	525	99.68	207	525	2	316	0.0e+00	509.2	COG0519	GMP synthase, PP-ATPase domain/subunit	315
2904406326	487	92.2	1	210	10	210	1.0e-117	171.1	COG0516	IMP dehydrogenase/GMP reductase	170
2904406326	487	99.54	255	476	1	217	1.0e-117	220	COG0516	IMP dehydrogenase/GMP reductase	170
2904406328	715	99.8	43	663	1	497	0.0e+00	538.9	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
2904406331	599	83.66	1	598	108	696	0.0e+00	700.2	COG1523	Pullulanase/glycogen debranching enzyme	697
2904406332	272	76.35	4	153	36	148	1.5e-27	90.2	COG5501	Predicted secreted protein	148
2904406333	309	78.46	36	305	29	232	5.9e-25	82.4	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2904406334	301	98.67	1	301	1	297	1.7e-55	183.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904406335	565	89.16	13	172	13	160	4.8e-26	84.8	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2904406335	565	95.05	159	565	15	417	8.5e-123	403.6	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2904406336	925	21.57	9	224	3	213	0.0e+00	169.4	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2904406336	925	69.12	222	923	262	937	0.0e+00	745.8	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2904406337	621	81.5	6	620	144	773	0.0e+00	477.9	COG4993	Glucose dehydrogenase	773
2904406338	290	63.6	6	263	41	220	4.6e-11	36.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904406339	496	97.84	1	496	11	508	0.0e+00	696.3	COG1190	Lysyl-tRNA synthetase (class II)	502
2904406340	289	99.16	52	289	1	237	7.4e-112	366.8	COG1186	Protein chain release factor B	239
2904406341	106	97.2	1	103	2	105	2.4e-28	92.5	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2904406342	151	93.38	3	150	3	143	1.2e-46	152.6	COG0822	NifU homolog involved in Fe-S cluster formation	150
2904406343	437	98.78	32	436	3	406	0.0e+00	545.7	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
2904406344	439	74.65	21	426	98	421	4.2e-64	211.2	COG0719	Fe-S cluster assembly scaffold protein SufB	412
2904406345	252	96.83	1	251	3	246	1.6e-106	349.3	COG0396	Fe-S cluster assembly ATPase SufC	251
2904406346	481	99.77	37	479	1	433	0.0e+00	529.8	COG0719	Fe-S cluster assembly scaffold protein SufB	412
2904406347	153	90.67	2	147	2	137	8.3e-35	114.2	COG1959	DNA-binding transcriptional regulator, IscR family	150
2904406348	567	83.13	23	561	83	560	2.8e-122	403.6	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
2904406349	167	88.65	1	167	19	182	8.5e-54	176.7	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
2904406350	226	90.83	1	225	3	210	8.2e-88	288.1	COG4229	Enolase-phosphatase E1 involved in merthionine salvage	229
2904406351	186	97.24	1	185	1	176	1.8e-64	211	COG1791	Acireductone dioxygenase (methionine salvage), cupin superfamily	181
2904406352	204	83.48	1	202	3	189	1.7e-43	143	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2904406353	623	93.35	3	620	41	728	8.0e-126	414	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
2904406354	1221	99.65	5	1189	5	1152	0.0e+00	793	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2904406355	331	77.89	140	327	41	195	1.6e-40	133.4	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2904406357	342	65.67	204	334	19	106	2.1e-07	25.2	COG3335	Transposase	132
2904406357	342	94.24	4	155	8	138	1.6e-17	57.9	COG3415	Transposase	138
2904406358	1085	97.5	1	1079	2	1053	0.0e+00	957.5	COG1330	Exonuclease V gamma subunit	1078
2904406359	404	83.02	9	372	1	357	7.9e-49	161.2	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2904406361	172	98.11	3	172	4	159	5.9e-31	101.6	COG1580	Flagellar basal body-associated protein FliL	159
2904406362	344	97.9	1	335	3	328	2.4e-111	366.2	COG1868	Flagellar motor switch protein FliM	332
2904406363	158	87.23	4	147	19	141	1.8e-37	123.3	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
2904406364	139	80	18	139	18	129	4.9e-20	66.1	COG3190	Flagellar biogenesis protein FliO	137
2904406365	255	94.38	3	253	14	248	1.8e-95	313.3	COG1338	Flagellar biosynthetic protein FliP	248
2904406367	89	98.88	1	89	1	88	1.4e-35	115.6	COG1987	Flagellar biosynthesis protein FliQ	89
2904406368	256	97.67	1	256	2	253	1.1e-70	232.3	COG1684	Flagellar biosynthesis protein FliR	258
2904406369	380	97.52	1	362	2	355	5.9e-124	407.9	COG1377	Flagellar biosynthesis protein FlhB	363
2904406370	697	96.99	2	696	20	695	0.0e+00	938.8	COG1298	Flagellar biosynthesis pathway, component FlhA	696
2904406371	499	98.55	1	485	1	408	4.1e-104	342	COG1419	Flagellar biosynthesis GTPase FlhF	407
2904406372	276	97.37	6	271	3	261	2.1e-64	211.8	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
2904406373	259	88.49	5	239	28	250	2.9e-71	234.2	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
2904406374	128	94.74	2	128	5	130	1.4e-31	103.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2904406375	245	98.16	26	245	5	217	1.8e-63	208.3	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2904406376	738	98.41	1	738	5	746	0.0e+00	697.1	COG0643	Chemotaxis protein histidine kinase CheA	716
2904406377	349	96.59	2	349	2	341	4.4e-118	388.7	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2904406378	247	92.88	1	247	1	248	1.4e-80	264.3	COG1291	Flagellar motor component MotA	266
2904406379	297	98.52	1	260	1	266	6.0e-55	181.1	COG1360	Flagellar motor protein MotB	244
2904406380	267	97.35	1	259	2	258	7.5e-66	216.9	COG1192	Cellulose biosynthesis protein BcsQ	259
2904406381	211	84.24	57	208	15	153	6.0e-14	45.7	COG0835	Chemotaxis signal transduction protein	165
2904406382	158	87.88	1	157	14	158	5.0e-50	163.6	COG0835	Chemotaxis signal transduction protein	165
2904406385	205	97.52	1	194	5	201	4.1e-31	102.6	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
2904406386	551	92.73	11	306	20	287	2.6e-23	77.4	COG1276	Putative copper export protein	289
2904406387	129	92.91	5	128	8	125	1.4e-13	45.4	COG2372	Copper-binding protein CopC (methionine-rich)	127
2904406388	462	92.84	14	442	26	401	7.6e-125	410.7	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2904406389	875	46.53	18	436	388	729	1.7e-52	98.5	COG1033	Predicted exporter protein, RND superfamily	727
2904406389	875	73.61	599	875	187	727	1.7e-52	77.7	COG1033	Predicted exporter protein, RND superfamily	727
2904406390	235	26.27	26	194	146	207	8.6e-04	9.7	COG0813	Purine-nucleoside phosphorylase	236
2904406391	655	7.93	3	89	343	383	9.0e-85	1.9	COG1657	Squalene cyclase	517
2904406391	655	98.45	111	652	3	511	9.0e-85	275.5	COG1657	Squalene cyclase	517
2904406392	349	92.73	1	317	15	282	5.2e-42	138.4	COG1562	Phytoene/squalene synthetase	288
2904406393	338	83.24	1	287	26	323	8.1e-35	114.7	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2904406394	148	75.66	2	148	42	184	2.9e-24	80.3	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
2904406395	244	69.96	27	237	19	174	2.6e-44	145.3	COG2091	Phosphopantetheinyl transferase	223
2904406396	239	98.13	1	239	5	267	1.0e-67	222.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904406397	260	47.35	13	253	7	176	3.7e-19	64.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2904406398	431	95.75	15	426	6	388	9.7e-77	252.4	COG0475	Kef-type K+ transport system, membrane component KefB	397
2904406399	213	99.07	1	213	1	212	1.8e-65	214.9	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
2904406400	191	93.56	3	190	2	190	5.1e-62	203.9	COG0164	Ribonuclease HII	199
2904406401	256	98.08	1	256	6	260	4.3e-113	371.1	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
2904406402	146	97.3	1	145	4	147	4.1e-52	170.2	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2904406403	169	94.71	1	166	8	168	5.5e-31	102.2	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
2904406404	740	96.77	1	740	26	774	0.0e+00	727.3	COG4775	Outer membrane protein assembly factor BamA	766
2904406405	242	93.47	6	242	5	233	4.8e-62	203.8	COG0704	Phosphate uptake regulator	240
2904406406	359	98.32	10	359	4	355	6.0e-128	421.1	COG2933	23S rRNA C2498 (ribose-2'-O)-methylase RlmM	358
2904406407	335	97.57	4	333	3	323	0.0e+00	436.3	COG1087	UDP-glucose 4-epimerase	329
2904406408	419	98.03	9	412	5	403	0.0e+00	469.2	COG0303	Molybdopterin biosynthesis enzyme	404
2904406409	179	98.15	8	171	2	160	1.6e-43	142.9	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
2904406410	336	99.07	1	335	2	319	1.8e-87	288.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2904406411	426	95.18	2	423	9	423	0.0e+00	460.6	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
2904406412	464	84	258	464	36	224	7.5e-76	248.2	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2904406413	701	14.1	2	82	143	175	5.9e-02	7.5	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
2904406413	701	17.95	225	288	32	73	5.9e-02	2.6	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
2904406413	701	32.05	129	256	154	228	5.9e-02	3.5	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
2904406413	701	77.16	297	692	86	389	1.9e-34	113.5	COG0642	Signal transduction histidine kinase	336
2904406414	450	97.64	1	450	4	459	0.0e+00	496.1	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904406415	918	64.95	397	601	105	343	4.4e-59	50.1	COG0457	Tetratricopeptide (TPR) repeat	291
2904406415	918	68.75	5	242	102	354	4.4e-59	49.1	COG0457	Tetratricopeptide (TPR) repeat	291
2904406415	918	70.11	227	464	48	305	4.4e-59	52.5	COG0457	Tetratricopeptide (TPR) repeat	291
2904406415	918	84.24	568	916	36	345	4.4e-59	71.2	COG0457	Tetratricopeptide (TPR) repeat	291
2904406416	230	25.95	99	226	147	214	1.0e-16	2.8	COG3103	Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family	205
2904406416	230	48.09	6	166	5	130	1.0e-16	53.3	COG3103	Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family	205
2904406417	565	98.1	1	562	9	575	0.0e+00	731.4	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2904406418	388	96.41	2	385	14	416	3.3e-81	267.7	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2904406419	446	94.12	295	444	2	145	3.8e-51	166.4	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
2904406419	446	99.62	25	291	1	264	9.9e-75	245.2	COG0548	Acetylglutamate kinase	265
2904406420	490	98.57	1	490	1	482	0.0e+00	494.5	COG0297	Glycogen synthase	487
2904406423	151	68.67	28	149	23	125	6.1e-06	20.7	COG1017	Hemoglobin-like flavoprotein	150
2904406425	738	96.29	31	737	26	751	0.0e+00	528.8	COG4772	Outer membrane receptor for Fe3+-dicitrate	753
2904406426	401	57.33	18	399	91	348	2.1e-15	50.4	COG0439	Biotin carboxylase	449
2904406427	604	80.4	6	572	20	503	8.2e-47	151.7	COG4264	Siderophore synthetase component	602
2904406428	390	48.83	203	388	4	190	7.8e-22	28.8	COG0477	MFS family permease	338
2904406428	390	52.74	5	207	8	209	7.8e-22	48.7	COG0477	MFS family permease	338
2904406429	607	93.36	14	601	16	577	1.5e-99	328.1	COG4264	Siderophore synthetase component	602
2904406430	410	93.67	4	399	23	392	8.1e-84	275.8	COG0019	Diaminopimelate decarboxylase	394
2904406431	254	98.82	1	254	3	254	2.4e-76	250.7	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
2904406432	345	35.44	1	168	9	165	4.6e-30	43	COG3182	Uncharacterized iron-regulated membrane protein	442
2904406432	345	37.02	165	345	8	171	4.6e-30	60	COG3182	Uncharacterized iron-regulated membrane protein	442
2904406433	348	21.49	234	344	377	480	1.6e-22	52.1	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904406433	348	22.73	79	228	68	177	1.6e-22	23.1	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904406435	225	91.71	17	216	8	195	3.5e-51	167.9	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2904406436	949	63.56	44	925	4	575	8.3e-62	201.2	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
2904406437	785	72.34	7	423	3	342	2.1e-46	153.1	COG0515	Serine/threonine protein kinase	384
2904406438	178	100	1	149	1	136	1.9e-31	103.2	COG1943	REP element-mobilizing transposase RayT	136
2904406440	523	17.01	211	472	187	227	3.7e-04	10	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
2904406440	523	33.2	26	166	3	82	3.7e-04	3.8	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
2904406441	497	60.82	10	256	10	203	3.4e-20	66.5	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2904406444	737	10.74	27	208	333	393	2.1e-44	5.4	COG2303	Choline dehydrogenase or related flavoprotein	542
2904406444	737	11.97	588	737	489	556	2.1e-44	59.2	COG2303	Choline dehydrogenase or related flavoprotein	542
2904406444	737	50.18	209	504	6	290	2.1e-44	78.6	COG2303	Choline dehydrogenase or related flavoprotein	542
2904406445	282	43.85	8	225	58	164	2.1e-13	44.2	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2904406446	389	94.74	1	383	16	393	9.2e-38	123.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2904406448	539	82.33	10	473	6	415	2.3e-38	126.6	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
2904406449	87	93.41	1	86	5	89	1.9e-13	44.9	COG2002	Bifunctional DNA-binding transcriptional regulator of stationary/sporulation/toxin gene expression and antitoxin component of the YhaV-PrlF toxin-antitoxin module	89
2904406450	129	95.38	1	123	2	125	5.5e-14	46.6	COG5611	Predicted nucleic-acid-binding protein, contains PIN domain	130
2904406451	69	80.82	1	69	9	67	4.3e-11	37	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
2904406452	407	99.8	18	407	1	509	6.9e-72	237.4	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2904406453	239	97.35	5	232	2	221	1.6e-88	290	COG1136	ABC-type lipoprotein export system, ATPase component	226
2904406454	377	91.54	1	361	16	372	1.9e-57	189.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904406455	506	90.22	13	498	38	452	2.3e-89	294.7	COG1538	Outer membrane protein TolC	457
2904406456	146	87.16	7	144	5	133	6.5e-12	39.6	COG5612	Uncharacterized membrane protein	148
2904406458	230	94.62	55	230	4	179	1.4e-44	146.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2904406459	269	64.39	47	269	115	331	7.5e-42	137.5	COG1723	Uncharacterized protein, Rmd1/YagE family	331
2904406461	261	96.21	1	261	5	258	2.3e-54	179.3	COG1192	Cellulose biosynthesis protein BcsQ	259
2904406462	453	84.77	258	452	9	175	3.4e-76	55.1	COG2059	Chromate transport protein ChrA	195
2904406462	453	89.34	15	229	6	181	3.4e-76	202.3	COG2059	Chromate transport protein ChrA	195
2904406463	196	95.03	21	195	4	175	1.5e-64	211.1	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
2904406464	364	99.43	1	352	1	348	0.0e+00	477.1	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
2904406465	292	96.17	8	292	6	281	0.0e+00	454.6	COG4208	ABC-type sulfate transport system, permease component	287
2904406466	273	97.45	1	273	4	270	1.2e-109	359.8	COG0555	ABC-type sulfate transport system, permease component	274
2904406467	444	69.7	39	436	61	412	2.3e-52	172.2	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2904406469	1083	45.65	12	181	176	343	1.0e-50	40.8	COG0457	Tetratricopeptide (TPR) repeat	291
2904406469	1083	64.95	318	542	106	344	1.0e-50	52.7	COG0457	Tetratricopeptide (TPR) repeat	291
2904406469	1083	65.22	145	351	104	343	1.0e-50	55.8	COG0457	Tetratricopeptide (TPR) repeat	291
2904406469	1083	76.09	454	1072	7	286	1.0e-50	32.4	COG0457	Tetratricopeptide (TPR) repeat	291
2904406472	285	71.6	42	281	56	239	2.4e-13	43.3	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2904406473	347	92.26	2	347	24	345	0.0e+00	506	COG1613	ABC-type sulfate transport system, periplasmic component	348
2904406474	523	88.73	103	523	48	425	1.7e-22	70.9	COG3746	Phosphate-selective porin	426
2904406475	63	68.52	10	57	11	47	1.8e-19	63.2	COG5583	Uncharacterized protein	54
2904406477	428	84.23	3	425	3	408	2.7e-35	116	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2904406478	481	89.34	5	479	37	388	2.7e-45	147.7	COG0642	Signal transduction histidine kinase	336
2904406479	464	97.64	2	464	6	461	0.0e+00	463.5	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904406480	556	90.23	12	550	19	526	3.1e-106	349.9	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2904406483	628	59.39	155	597	219	588	4.9e-18	56.7	COG3211	Secreted phosphatase, PhoX family	616
2904406485	209	97.49	1	209	5	198	5.0e-57	187.3	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
2904406486	420	99.28	5	420	3	416	0.0e+00	605.6	COG0014	Gamma-glutamyl phosphate reductase	417
2904406487	343	97.9	3	333	3	329	1.6e-78	258.4	COG1466	DNA polymerase III, delta subunit	334
2904406488	174	87.85	1	172	3	161	6.9e-27	88.4	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
2904406489	865	99.64	1	865	4	823	0.0e+00	1103.5	COG0495	Leucyl-tRNA synthetase	814
2904406490	213	97.84	1	192	3	183	2.2e-72	236.6	COG1704	Uncharacterized conserved protein	185
2904406491	279	96.04	1	279	12	278	1.7e-75	248.1	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
2904406492	169	11.74	18	57	10	34	7.7e-28	4.2	COG3762	Uncharacterized membrane protein	213
2904406492	169	51.17	55	168	104	212	7.7e-28	87.3	COG3762	Uncharacterized membrane protein	213
2904406493	502	85.47	15	496	4	462	1.3e-93	308.9	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
2904406495	891	93.37	2	886	48	949	0.0e+00	798.2	COG0474	Magnesium-transporting ATPase (P-type)	917
2904406497	560	61.68	245	549	147	389	1.7e-67	221	COG0642	Signal transduction histidine kinase	336
2904406497	560	93.41	9	184	11	180	3.2e-18	59.7	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2904406498	154	85.71	2	140	6	119	5.3e-25	81.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2904406499	494	72.34	41	494	101	385	3.4e-54	177.4	COG0642	Signal transduction histidine kinase	336
2904406500	206	99.53	2	205	1	210	3.3e-59	194.2	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2904406501	551	15.2	488	547	318	374	1.4e-49	51.2	COG4585	Signal transduction histidine kinase	365
2904406501	551	44	76	470	147	311	1.4e-49	116.8	COG4585	Signal transduction histidine kinase	365
2904406506	133	82.14	7	132	18	132	4.8e-27	88.1	COG1832	Predicted CoA-binding protein	140
2904406507	188	92.08	1	188	5	190	1.4e-46	152.6	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
2904406508	332	89.77	8	332	18	289	9.2e-42	137.1	COG1234	Ribonuclease BN, tRNA processing enzyme	292
2904406509	203	97.65	1	198	3	210	3.1e-41	135.8	COG0655	Multimeric flavodoxin WrbA	207
2904406511	157	91.25	1	149	8	153	1.5e-28	93.9	COG4244	Uncharacterized membrane protein	160
2904406512	114	83.33	1	114	23	142	1.1e-27	91.4	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2904406513	128	97.4	47	128	2	76	1.4e-09	30.2	COG1531	Uncharacterized protein, UPF0248 family	77
2904406514	256	26.78	94	155	8	56	7.0e-11	15.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904406514	256	26.78	159	248	77	125	7.0e-11	19.3	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904406515	935	90.86	19	809	2	776	0.0e+00	575.8	COG3072	Adenylate cyclase	853
2904406516	556	95.03	1	556	22	480	9.3e-71	231.7	COG0471	Di- and tricarboxylate transporter	461
2904406517	337	98.52	1	335	3	335	3.1e-98	322.8	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
2904406519	233	93.75	10	232	6	215	5.9e-45	147.4	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
2904406521	361	97.65	6	358	3	335	8.3e-112	367.8	COG0430	RNA 3'-terminal phosphate cyclase	341
2904406522	574	98.76	338	573	2	240	1.8e-61	201.6	COG1387	Histidinol phosphatase or related hydrolase of the PHP family	237
2904406522	574	99.08	1	324	4	326	2.2e-95	313.4	COG1796	DNA polymerase/3'-5' exonuclease PolX	326
2904406523	208	97.5	2	201	3	197	2.8e-68	223.5	COG0218	GTP-binding protein EngB required for normal cell division	200
2904406524	242	66.67	146	242	24	113	5.5e-54	78.1	COG2863	Cytochrome c553	121
2904406524	242	97.78	43	162	3	134	5.5e-54	104.5	COG2863	Cytochrome c553	121
2904406525	215	58.63	13	207	88	233	1.8e-10	34.9	COG1651	Protein-disulfide isomerase	244
2904406526	275	97.28	24	269	7	256	2.4e-41	135.1	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2904406527	411	95.62	3	256	4	243	7.3e-79	258.9	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
2904406529	427	98	3	406	4	395	2.5e-97	320	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
2904406530	409	91.16	4	409	19	379	1.1e-51	169.6	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
2904406531	274	98.4	14	264	3	248	5.4e-62	203.4	COG1587	Uroporphyrinogen-III synthase	248
2904406532	307	98.7	2	307	2	304	1.7e-123	405.8	COG0181	Porphobilinogen deaminase	307
2904406533	253	98.79	1	246	2	246	7.2e-62	203.6	COG3279	DNA-binding response regulator, LytR/AlgR family	244
2904406535	314	99.67	1	305	1	305	1.1e-83	275.5	COG1131	ABC-type multidrug transport system, ATPase component	293
2904406536	248	89.86	1	240	2	258	5.7e-19	62.5	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
2904406537	494	77.41	11	494	76	493	7.5e-21	67	COG3225	ABC-type uncharacterized transport system involved in gliding motility, auxiliary component	538
2904406539	271	100	1	271	1	274	7.5e-104	341.5	COG0266	Formamidopyrimidine-DNA glycosylase	273
2904406540	337	99	1	337	1	297	0.0e+00	444.4	COG1023	6-phosphogluconate dehydrogenase (decarboxylating)	300
2904406542	454	88.12	16	312	21	287	4.7e-44	144.7	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2904406543	386	89.01	17	386	40	355	9.1e-65	213.2	COG5621	Predicted secreted hydrolase	354
2904406544	474	19.51	422	474	109	140	2.0e-08	5.4	COG2010	Cytochrome c, mono- and diheme variants	150
2904406544	474	34.76	209	362	33	89	2.0e-08	17.3	COG2010	Cytochrome c, mono- and diheme variants	150
2904406545	184	49.83	1	173	1	144	2.3e-19	63.9	COG5483	Uncharacterized conserved protein, DUF488 family	289
2904406548	299	96.75	9	296	3	300	1.3e-71	235	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
2904406549	304	94.74	5	268	13	264	3.8e-85	279.6	COG3228	Mlc titration factor MtfA, regulates ptsG expression	266
2904406551	168	81.01	38	168	29	156	3.6e-33	108.1	COG4454	Uncharacterized copper-binding protein, cupredoxin-like subfamily	158
2904406552	412	16.13	271	372	175	239	1.6e-11	19.1	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904406552	412	33.25	5	243	150	283	1.6e-11	18.4	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904406553	352	98.13	14	347	3	317	4.4e-56	184.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2904406554	380	71.81	8	363	27	296	1.9e-37	123.4	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2904406555	175	20.19	1	171	659	825	5.4e-34	111.5	COG4449	Predicted protease, Abi (CAAX) family	827
2904406558	317	83.33	1	317	47	321	1.1e-83	275.6	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2904406559	173	85.28	2	171	2	169	3.1e-17	57.2	COG1988	Membrane-bound metal-dependent hydrolase YbcI, DUF457 family	190
2904406560	195	72.66	1	195	67	252	3.7e-58	191.4	COG0121	Predicted glutamine amidotransferase	252
2904406562	295	97.59	7	292	7	289	2.7e-85	280	COG0382	4-hydroxybenzoate polyprenyltransferase	289
2904406563	193	92.66	14	192	11	174	9.4e-35	113.7	COG3161	4-hydroxybenzoate synthetase (chorismate-pyruvate lyase)	174
2904406564	261	94.4	2	258	5	257	1.0e-78	258.4	COG0413	Ketopantoate hydroxymethyltransferase	268
2904406565	694	98.53	3	687	9	676	0.0e+00	846.1	COG1200	RecG-like helicase	677
2904406566	128	97.06	1	128	3	134	2.1e-38	125.6	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2904406567	738	99.03	8	721	8	724	0.0e+00	889.3	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2904406568	97	86.49	1	72	1	64	8.9e-24	77.5	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
2904406569	592	66.24	8	132	6	109	2.0e-09	30.5	COG1225	Peroxiredoxin	157
2904406569	592	98.74	202	592	5	397	0.0e+00	507.1	COG0126	3-phosphoglycerate kinase	395
2904406570	540	97.46	2	522	5	503	0.0e+00	595.8	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
2904406571	217	96.57	4	206	3	199	8.9e-42	137.1	COG3165	Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain	204
2904406572	249	99.16	11	249	2	238	1.5e-90	296.6	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2904406573	125	95.83	2	121	4	118	3.6e-48	156.7	COG3536	Uncharacterized conserved protein, DUF971 family	120
2904406574	441	100	1	441	1	444	0.0e+00	729.5	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
2904406575	187	98.88	3	180	2	177	2.6e-88	288.5	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
2904406577	399	99.49	7	396	2	392	2.5e-113	373.1	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
2904406578	734	22.48	26	126	12	60	2.3e-23	13.9	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2904406578	734	55.5	155	292	1	121	2.3e-23	61	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2904406579	451	20.27	358	449	261	334	1.2e-127	23	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2904406579	451	93.42	6	364	19	359	1.2e-127	399.2	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2904406581	307	99.3	7	296	2	284	2.3e-93	307.3	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2904406582	952	95.02	6	952	40	954	0.0e+00	1023.3	COG1391	Glutamine synthetase adenylyltransferase	963
2904406583	238	31.79	20	225	226	342	3.0e-12	41.5	COG0457	Tetratricopeptide (TPR) repeat	291
2904406585	1063	92.13	1	1061	4	1069	0.0e+00	1009.9	COG0587	DNA polymerase III, alpha subunit	1139
2904406586	1445	95.61	1	871	4	830	0.0e+00	829.4	COG1201	Lhr-like helicase	814
2904406587	640	63.96	334	634	136	387	6.9e-68	224.3	COG0642	Signal transduction histidine kinase	336
2904406588	440	98.78	8	429	2	406	1.3e-122	403.8	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2904406589	447	93.39	14	257	17	242	2.2e-20	65.6	COG2202	PAS domain	232
2904406589	447	97.27	265	446	6	183	2.3e-58	190.7	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904406590	723	93.78	11	720	46	724	0.0e+00	784	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2904406591	463	97.02	15	411	2	327	5.9e-67	220.3	COG1035	Coenzyme F420-reducing hydrogenase, beta subunit	332
2904406594	203	91.39	1	200	2	192	4.2e-44	144.9	COG0406	Broad specificity phosphatase PhoE	208
2904406595	295	75.7	1	295	56	379	2.8e-53	175.6	COG3664	Beta-xylosidase	428
2904406596	265	56.99	10	263	29	187	1.4e-12	42.5	COG0500	SAM-dependent methyltransferase	257
2904406597	361	99.47	1	357	3	377	0.0e+00	458.3	COG1260	Myo-inositol-1-phosphate synthase	362
2904406598	964	69.98	39	378	122	403	2.6e-42	138.9	COG0506	Proline dehydrogenase	391
2904406598	964	97.08	478	957	12	476	0.0e+00	451	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2904406599	699	85.76	3	288	35	299	8.3e-53	173.2	COG0010	Arginase family enzyme	305
2904406599	699	97.78	290	695	6	401	0.0e+00	465.5	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2904406600	94	7.17	16	87	739	795	2.6e-06	20.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904406601	277	96.82	3	276	10	283	9.0e-93	304.9	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2904406602	294	94.63	2	294	11	292	6.4e-100	328.5	COG1175	ABC-type sugar transport system, permease component	295
2904406603	417	97.97	1	409	8	441	1.7e-66	219.7	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2904406604	753	94.69	3	748	30	743	9.1e-112	368.5	COG4772	Outer membrane receptor for Fe3+-dicitrate	753
2904406605	1714	8.06	1081	1172	389	427	1.1e-05	2.7	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904406605	1714	14.46	95	288	74	143	1.1e-05	9.2	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904406605	1714	14.88	401	499	406	477	1.1e-05	10.6	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904406615	435	51.85	61	421	149	442	1.3e-29	98	COG1404	Serine protease, subtilisin family	508
2904406616	209	94.62	22	200	4	179	2.6e-38	125.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2904406617	106	24.11	8	98	161	228	1.4e-04	15.2	COG1091	dTDP-4-dehydrorhamnose reductase	281
2904406622	45	27.21	2	45	10	46	1.3e-03	13.3	COG1943	REP element-mobilizing transposase RayT	136
2904406623	46	30.15	1	46	56	96	2.1e-04	15.8	COG1943	REP element-mobilizing transposase RayT	136
2904406625	73	29.52	9	73	68	116	1.3e-03	12.9	COG1329	RNA polymerase-interacting regulator, CarD/CdnL/TRCF family	166
2904406631	469	93.5	4	464	8	467	8.1e-75	246.2	COG0531	Amino acid transporter	466
2904406633	223	99.42	32	223	2	171	3.2e-57	185.6	COG4675	Microcystin-dependent protein  (function unknown)	170
2904406634	336	20.85	35	119	195	263	2.5e-32	33.8	COG0790	TPR repeat	292
2904406634	336	48.64	105	266	97	257	2.5e-32	82.6	COG0790	TPR repeat	292
2904406636	197	89	1	192	8	193	1.0e-24	82.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904406638	141	25.31	12	135	116	217	1.1e-04	15.4	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904406639	241	46.03	10	226	82	249	3.4e-14	46.9	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2904406645	205	62.75	1	193	6	197	1.3e-41	137.2	COG1131	ABC-type multidrug transport system, ATPase component	293
2904406648	191	74.81	63	187	22	122	1.4e-03	11.6	COG3791	Uncharacterized conserved protein	133
2904406651	339	78.9	14	193	41	212	9.0e-71	231.4	COG1535	Isochorismate hydrolase	218
2904406652	40	18.45	19	40	74	92	1.2e-10	12.9	COG3461	Uncharacterized protein	103
2904406652	40	22.33	1	25	26	48	1.2e-10	25.8	COG3461	Uncharacterized protein	103
2904406654	401	96.82	2	401	4	399	2.2e-08	28.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904406656	460	89.38	72	443	14	358	2.7e-41	134.8	COG2327	Polysaccharide pyruvyl transferase family protein WcaK	385
2904406657	487	96.47	6	475	4	468	2.6e-49	162.1	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2904406658	418	96.82	12	418	3	398	2.8e-13	44.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904406659	380	95.59	41	380	13	337	1.7e-60	199.1	COG4246	Uncharacterized protein	340
2904406661	404	91.93	11	384	29	404	4.2e-30	99.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904406662	156	61.05	12	135	67	182	4.9e-32	105.3	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2904406664	291	70.28	40	291	40	240	1.0e-34	114.2	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2904406665	468	96.56	1	436	16	464	3.0e-79	261	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2904406666	265	25.7	186	263	132	195	5.8e-56	41.3	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2904406666	265	70.28	8	191	41	215	5.8e-56	145.1	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2904406667	411	98.67	181	411	4	225	1.0e-81	267.4	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2904406670	597	99.66	1	588	1	584	0.0e+00	856.7	COG0173	Aspartyl-tRNA synthetase	585
2904406671	95	82.93	1	94	8	75	8.9e-26	83.3	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
2904406672	264	99.59	13	262	2	244	7.0e-67	219.7	COG4582	Cell division protein ZapD, interacts with FtsZ	244
2904406673	197	97.01	1	196	2	196	5.0e-66	216.4	COG0237	Dephospho-CoA kinase	201
2904406674	293	93.75	14	288	6	245	3.5e-73	240.5	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
2904406675	404	99.25	7	404	3	397	0.0e+00	477.2	COG1459	Type II secretory pathway, component PulF	397
2904406676	571	97.44	67	571	13	507	0.0e+00	605.5	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2904406677	498	64.01	37	257	21	205	6.3e-28	90.9	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
2904406678	950	99.77	1	949	2	882	0.0e+00	1294.8	COG0525	Valyl-tRNA synthetase	877
2904406679	146	97.92	1	145	1	141	1.7e-31	103.4	COG2927	DNA polymerase III, chi subunit	144
2904406680	495	96.1	4	495	19	486	0.0e+00	566.8	COG0260	Leucyl aminopeptidase	485
2904406681	380	98.9	17	366	2	362	1.7e-56	186	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
2904406682	356	99.45	1	355	1	363	1.6e-68	225.6	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
2904406683	127	60.96	1	105	36	124	3.4e-16	53.8	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2904406684	247	75.16	3	246	4	233	2.6e-75	247.7	COG1131	ABC-type multidrug transport system, ATPase component	293
2904406685	263	18.49	3	82	54	102	3.2e-09	3.5	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2904406685	263	79.62	27	252	44	254	3.2e-09	29.2	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2904406686	202	98.65	40	193	2	147	4.2e-35	114.2	COG0394	Protein-tyrosine-phosphatase	139
2904406688	500	96.79	2	499	12	523	0.0e+00	461.4	COG1640	4-alpha-glucanotransferase	520
2904406689	423	97.19	13	420	3	383	0.0e+00	520.1	COG0448	ADP-glucose pyrophosphorylase	393
2904406690	728	99.68	13	716	2	632	0.0e+00	866.6	COG0296	1,4-alpha-glucan branching enzyme	628
2904406691	493	98.16	2	482	2	481	0.0e+00	513.8	COG0297	Glycogen synthase	487
2904406693	835	9.61	16	157	2	50	7.8e-48	7.6	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2904406693	835	9.8	467	556	2	51	7.8e-48	7.3	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2904406693	835	24.9	185	382	380	506	7.8e-48	69.6	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2904406693	835	56.47	575	835	223	510	7.8e-48	92.4	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2904406694	247	96.9	26	247	2	220	5.8e-81	265.3	COG1136	ABC-type lipoprotein export system, ATPase component	226
2904406695	323	94.12	4	320	16	319	9.1e-93	304.7	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
2904406696	432	97.3	99	431	8	331	2.3e-54	171.4	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2904406697	381	84.57	18	174	15	151	2.4e-04	13.7	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904406698	89	93.83	3	84	5	80	1.7e-14	47.9	COG0236	Acyl carrier protein	80
2904406699	177	57.75	3	170	78	185	2.2e-25	84.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2904406700	534	62.81	2	447	237	643	2.5e-86	284.7	COG1020	Non-ribosomal peptide synthetase component F	642
2904406701	354	91.55	27	351	14	327	2.5e-34	112.7	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2904406703	587	99.46	8	584	2	553	0.0e+00	500.3	COG2192	Predicted carbamoyl transferase, NodU family	555
2904406705	403	93.11	2	403	25	416	2.8e-109	359.9	COG2124	Cytochrome P450	411
2904406706	245	83.2	1	226	10	222	5.3e-43	139.4	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2904406707	141	94.34	1	141	7	156	3.7e-26	87	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2904406708	692	46.16	297	692	429	795	1.7e-52	102.2	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904406708	692	49.43	7	428	35	427	1.7e-52	80.1	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904406709	638	99.33	6	601	1	597	0.0e+00	936.3	COG0465	ATP-dependent Zn proteases	596
2904406710	446	97.28	1	446	10	474	0.0e+00	447.1	COG1109	Phosphomannomutase	464
2904406711	102	81.51	1	100	27	145	3.6e-12	42	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2904406712	81	96.1	1	76	1	74	2.7e-38	123.8	COG1923	sRNA-binding regulator protein Hfq	77
2904406713	424	98.54	6	417	3	408	0.0e+00	509	COG2262	50S ribosomal subunit-associated GTPase HflX	411
2904406714	391	97.01	47	351	6	297	3.0e-69	227.7	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2904406715	286	96.68	2	286	7	297	3.3e-70	230.9	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2904406716	397	94.63	5	391	2	371	4.9e-106	348.8	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
2904406717	430	99.53	2	430	2	429	0.0e+00	621.2	COG0104	Adenylosuccinate synthase	430
2904406719	746	99.72	27	731	2	710	0.0e+00	804.6	COG0557	Exoribonuclease R	706
2904406720	251	91.63	1	248	21	261	4.2e-80	263.1	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2904406722	344	98.55	4	343	2	342	0.0e+00	433.3	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
2904406723	424	99.07	1	424	1	427	0.0e+00	594.7	COG0172	Seryl-tRNA synthetase	429
2904406724	134	41.13	15	133	82	183	1.0e-48	160.6	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
2904406726	111	97.27	2	111	4	110	2.1e-45	147.5	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2904406728	840	78.4	649	834	29	195	1.9e-13	44.6	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2904406728	840	92.09	23	574	8	531	0.0e+00	584.5	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2904406729	365	97.58	5	364	6	328	6.5e-36	117.6	COG0530	Ca2+/Na+ antiporter	320
2904406730	99	94.95	3	99	3	96	1.5e-23	76.9	COG1359	Quinol monooxygenase YgiN	100
2904406731	242	89.76	4	241	5	232	3.8e-57	187.3	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2904406732	178	60.98	32	176	51	150	1.8e-17	57.9	COG2010	Cytochrome c, mono- and diheme variants	150
2904406733	131	30.15	84	131	90	130	1.6e-07	13.9	COG3474	Cytochrome c2	135
2904406733	131	30.88	13	87	24	65	1.6e-07	10.2	COG3474	Cytochrome c2	135
2904406734	380	94.79	6	379	14	359	1.6e-126	416.4	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2904406737	393	95.38	1	381	13	384	3.4e-50	165.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904406738	1024	99.7	4	1016	2	1012	0.0e+00	976.8	COG0841	Multidrug efflux pump subunit AcrB	1009
2904406739	248	84.48	15	243	28	223	1.2e-34	114.5	COG0671	Membrane-associated phospholipid phosphatase	232
2904406740	373	93.89	29	371	11	348	1.7e-63	208.9	COG0628	Predicted PurR-regulated permease PerM	355
2904406741	180	93.98	17	150	5	129	1.1e-23	77.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
2904406742	303	90.82	9	293	13	299	6.4e-45	147.5	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2904406743	391	90.23	41	383	26	265	6.3e-67	220	COG0860	N-acetylmuramoyl-L-alanine amidase	231
2904406744	341	98.77	9	336	2	322	1.5e-100	330.9	COG3491	Isopenicillin N synthase and related dioxygenases	322
2904406746	329	20.31	251	324	236	301	2.6e-10	31	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2904406746	329	28	23	179	60	150	2.6e-10	1.6	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2904406747	326	60.7	141	311	40	161	9.4e-08	25.4	COG2370	Hydrogenase/urease accessory protein HupE	201
2904406749	2605	8.76	1916	2008	474	548	9.0e-45	36.4	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904406749	2605	10.03	1252	1334	163	193	6.1e-11	6.4	COG3386	Sugar lactone lactonase YvrE	307
2904406749	2605	13.59	391	453	113	154	6.1e-11	1.5	COG3386	Sugar lactone lactonase YvrE	307
2904406749	2605	24.27	1299	1394	118	192	6.1e-11	9.9	COG3386	Sugar lactone lactonase YvrE	307
2904406749	2605	32.48	1647	1916	2	279	9.0e-45	38.4	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904406749	2605	33.33	1400	1599	29	131	6.1e-11	21.8	COG3386	Sugar lactone lactonase YvrE	307
2904406749	2605	55.49	2011	2493	232	706	9.0e-45	84.5	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904406751	327	23.25	2	309	510	708	4.7e-21	68.7	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904406753	300	25.7	2	282	510	729	5.4e-21	67.4	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904406755	375	33.18	11	359	417	700	2.5e-22	70.9	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904406756	164	18.9	13	53	97	120	2.1e-03	2.8	COG4451	Ribulose bisphosphate carboxylase small subunit	127
2904406756	164	26.77	70	134	61	94	2.1e-03	7.2	COG4451	Ribulose bisphosphate carboxylase small subunit	127
2904406759	473	98.67	1	446	3	448	0.0e+00	566	COG1115	Na+/alanine symporter	452
2904406760	1106	67.51	706	1104	123	388	7.5e-67	220.9	COG0642	Signal transduction histidine kinase	336
2904406761	255	98.31	1	248	4	293	1.6e-39	130	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904406762	421	94.62	5	417	20	406	1.5e-51	170.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904406763	278	32.72	7	118	5	93	6.2e-27	40.7	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
2904406763	278	37.5	113	263	167	268	6.2e-27	46.5	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
2904406764	820	25.73	663	819	351	473	5.2e-37	21	COG1109	Phosphomannomutase	464
2904406764	820	47.28	364	618	8	233	5.2e-37	99	COG1109	Phosphomannomutase	464
2904406764	820	98.94	1	370	2	375	8.0e-102	334.8	COG1208	NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins	358
2904406765	805	79.46	295	770	73	397	2.8e-30	100	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904406766	169	93.98	6	139	6	130	6.5e-23	75.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2904406767	821	80.7	461	803	47	322	1.6e-47	156	COG0668	Small-conductance mechanosensitive channel	316
2904406770	411	54.86	80	365	13	187	2.3e-18	60.6	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2904406771	57	96.43	3	57	2	55	3.0e-24	78.9	COG0401	Uncharacterized membrane protein YqaE, homolog of Blt101, UPF0057 family	56
2904406774	40	25	1	40	49	84	1.4e-03	13.4	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2904406775	335	79.28	11	327	68	331	3.8e-79	260.5	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2904406776	784	98.77	31	585	4	485	0.0e+00	525.7	COG3119	Arylsulfatase A or related enzyme	475
2904406778	191	74.44	24	156	16	114	3.9e-21	69.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2904406779	454	83.51	11	405	26	334	1.9e-60	191.3	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
2904406781	331	60.81	59	226	5	139	3.6e-08	27.1	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2904406783	113	18.24	2	109	316	404	2.0e-19	64.7	COG3119	Arylsulfatase A or related enzyme	475
2904406785	113	64.96	7	109	13	101	3.0e-22	72.9	COG1695	DNA-binding transcriptional regulator, PadR family	138
2904406786	453	89.43	11	440	7	446	5.1e-63	207.3	COG0531	Amino acid transporter	466
2904406787	118	100	1	118	1	126	1.2e-24	81	COG1553	Sulfur relay (sulfurtransferase) complex TusBCD TusD component, DsrE family	126
2904406788	368	90.96	28	359	31	362	2.4e-88	290.5	COG1858	Cytochrome c peroxidase	364
2904406791	349	90.88	1	262	13	261	4.2e-48	158.1	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
2904406792	289	54.48	35	228	78	223	1.3e-30	100.6	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2904406793	340	16.5	195	292	280	346	5.4e-07	9.2	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
2904406793	340	26.11	3	157	44	149	5.4e-07	12	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
2904406794	398	77.51	3	398	88	404	3.9e-15	50.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904406796	380	77.26	4	379	91	406	3.0e-44	146.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904406797	630	99.45	1	630	1	545	0.0e+00	467.6	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2904406798	403	99.51	1	402	1	407	4.1e-46	152.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904406799	611	87.23	37	610	65	542	7.8e-71	233.2	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2904406800	318	86.19	18	302	11	241	2.6e-26	83.6	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2904406801	386	97.31	21	378	9	406	5.0e-46	152.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904406802	237	34.78	28	230	179	306	2.0e-06	22.7	COG0457	Tetratricopeptide (TPR) repeat	291
2904406803	315	71.57	2	290	4	227	3.8e-45	148.5	COG1216	Glycosyltransferase, GT2 family	305
2904406804	217	47.54	6	177	53	168	2.8e-18	60.2	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2904406806	577	95.27	427	573	3	143	1.3e-30	98.6	COG0394	Protein-tyrosine-phosphatase	139
2904406808	286	23.12	1	285	26	108	1.1e-19	65.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2904406809	481	88.38	2	464	10	435	8.5e-47	153.6	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2904406810	415	89.72	2	381	20	368	5.5e-31	101.8	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2904406811	292	19.52	227	288	154	194	1.4e-12	3.3	COG2945	Alpha/beta superfamily hydrolase	210
2904406811	292	43.81	7	144	16	107	1.4e-12	36.3	COG2945	Alpha/beta superfamily hydrolase	210
2904406812	226	33.22	3	215	56	153	1.1e-07	26.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904406813	81	91.36	2	81	6	79	3.5e-14	46.9	COG0236	Acyl carrier protein	80
2904406814	445	86.25	3	406	5	374	9.1e-14	44.7	COG3307	O-antigen ligase	424
2904406815	411	98.23	12	411	7	394	3.2e-88	290.2	COG0019	Diaminopimelate decarboxylase	394
2904406816	532	96.48	2	530	13	560	1.0e-104	345	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2904406818	1096	47.33	349	444	65	135	1.4e-10	3	COG5652	VanZ like family protein (function unknown)	148
2904406818	1096	59.33	11	150	53	141	1.4e-10	32.2	COG5652	VanZ like family protein (function unknown)	148
2904406820	360	89.54	5	349	3	336	1.4e-61	202.5	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2904406822	47	32.76	3	41	10	28	1.2e-03	13.1	COG5567	Predicted small periplasmic lipoprotein YifL (function unknown0	58
2904406825	123	91.34	1	123	10	125	1.4e-28	94.1	COG2372	Copper-binding protein CopC (methionine-rich)	127
2904406828	218	93.81	1	217	4	215	1.4e-58	192.1	COG1136	ABC-type lipoprotein export system, ATPase component	226
2904406830	291	94.43	1	290	14	301	1.4e-40	132.6	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
2904406832	184	48.17	20	151	60	138	8.2e-09	29.1	COG2010	Cytochrome c, mono- and diheme variants	150
2904406833	425	94.46	20	395	4	276	5.4e-40	130.7	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2904406835	235	93.42	1	233	3	215	6.2e-50	164.3	COG0705	Membrane associated serine protease, rhomboid family	228
2904406836	498	99.36	23	474	3	468	0.0e+00	433.1	COG0277	FAD/FMN-containing dehydrogenase	459
2904406837	353	14.07	267	353	403	468	5.8e-44	15.8	COG0277	FAD/FMN-containing dehydrogenase	459
2904406837	353	51.39	5	271	45	285	5.8e-44	127.7	COG0277	FAD/FMN-containing dehydrogenase	459
2904406838	401	97.51	15	401	4	394	3.0e-73	241.2	COG0247	Fe-S oxidoreductase	388
2904406840	457	99.32	1	442	2	439	0.0e+00	537.2	COG0621	tRNA A37 methylthiotransferase MiaB	437
2904406841	322	93.82	1	322	14	332	0.0e+00	453.1	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
2904406842	151	96.75	1	147	3	151	8.6e-48	156	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
2904406843	288	95.22	1	285	9	287	3.1e-116	381.8	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
2904406844	498	95.96	1	495	18	516	0.0e+00	462.3	COG0815	Apolipoprotein N-acyltransferase	518
2904406845	1302	64.25	812	1295	216	641	5.9e-113	372.1	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2904406845	1302	73.62	369	550	38	157	1.6e-03	10.8	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
2904406845	1302	92.48	1	231	5	127	9.8e-30	95.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2904406846	147	90.98	1	125	7	127	4.2e-32	105	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2904406847	381	66.5	9	381	127	388	1.3e-72	239.7	COG0642	Signal transduction histidine kinase	336
2904406849	401	93.64	1	400	27	409	8.8e-86	282.4	COG3876	Uncharacterized conserved protein YbbC, DUF1343 family	409
2904406850	178	94.71	5	178	4	164	1.5e-43	143	COG1795	Formaldehyde-activating enzyme nesessary for methanogenesis	170
2904406851	118	92.66	10	118	9	109	5.8e-31	101.4	COG3784	Uncharacterized conserved protein YdbL, DUF1318 family	109
2904406852	66	24.11	1	66	10	63	7.6e-04	13.4	COG5461	Type IV pilus biogenesis protein CpaD/CtpE	224
2904406854	124	11.76	15	108	176	207	8.3e-03	9.5	COG3183	Predicted restriction endonuclease, HNH family	272
2904406855	68	93.06	1	68	6	72	3.3e-21	69.9	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
2904406856	137	54.39	1	136	100	229	1.3e-31	104.1	COG1186	Protein chain release factor B	239
2904406857	221	98.14	1	220	1	211	3.7e-88	289.2	COG3132	Uncharacterized conserved protein YceH, UPF0502 family	215
2904406858	339	97.61	12	339	6	332	1.2e-75	248.6	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2904406859	106	27.66	2	100	121	211	2.9e-21	70.6	COG0724	 RNA recognition motif (RRM) domain	306
2904406860	89	27.05	2	89	122	210	4.5e-17	56.9	COG0724	 RNA recognition motif (RRM) domain	306
2904406862	90	24.32	2	86	122	201	9.1e-17	55.7	COG0724	 RNA recognition motif (RRM) domain	306
2904406865	629	98.72	1	629	9	627	0.0e+00	828.3	COG3158	K+ transporter	627
2904406867	791	66.21	312	785	201	639	1.8e-112	370.5	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2904406869	124	33.13	27	122	82	136	9.0e-07	22.8	COG1813	Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains	165
2904406870	130	32.58	1	59	114	171	4.2e-11	8.2	COG1633	Rubrerythrin	176
2904406870	130	41.01	53	130	5	77	4.2e-11	28.8	COG1633	Rubrerythrin	176
2904406872	468	85.38	1	250	16	237	6.3e-41	134.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2904406872	468	86.84	257	359	8	106	1.8e-37	39.9	COG0607	Rhodanese-related sulfurtransferase	110
2904406872	468	86.84	360	460	7	105	1.8e-37	79.7	COG0607	Rhodanese-related sulfurtransferase	110
2904406873	393	82.47	8	388	56	356	1.1e-98	324.6	COG1858	Cytochrome c peroxidase	364
2904406874	400	82.5	28	113	4	69	2.6e-04	14.9	COG0695	Glutaredoxin	80
2904406875	144	86.21	22	142	7	106	1.1e-19	64.7	COG3339	Uncharacterized membrane protein YkvA, DUF1232 family	116
2904406876	300	97.43	38	300	7	271	7.8e-68	223	COG0428	Zinc transporter ZupT	266
2904406877	471	72.73	51	252	67	242	3.7e-40	130.2	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2904406878	328	99.35	2	308	1	308	1.6e-40	133.3	COG0167	Dihydroorotate dehydrogenase	310
2904406879	1196	32.88	672	722	42	65	1.4e-12	17.3	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2904406879	1196	39.73	723	777	38	66	1.4e-12	23.7	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2904406879	1196	96.08	423	630	4	199	7.3e-44	143.5	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
2904406879	1196	99.48	4	407	2	381	4.4e-122	399.6	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
2904406879	1196	99.67	814	1180	2	299	4.9e-99	325.1	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
2904406880	546	7.21	461	506	5	37	4.6e-98	9.4	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2904406880	546	92.58	32	427	31	454	4.6e-98	318.3	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2904406881	656	86.32	9	624	96	726	0.0e+00	529.9	COG2217	Cation transport ATPase	713
2904406882	218	98.44	11	200	2	190	1.0e-74	244.4	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
2904406883	333	93.07	1	333	22	357	1.2e-68	225.9	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2904406884	212	59.5	2	209	15	180	1.3e-20	68.5	COG0500	SAM-dependent methyltransferase	257
2904406885	234	98.26	6	234	3	228	6.4e-93	305	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
2904406888	233	97.24	5	233	3	249	1.5e-61	201.7	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
2904406889	262	93.12	2	259	16	272	1.8e-45	149.5	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2904406891	333	97.97	1	333	6	343	2.4e-110	363.4	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
2904406892	461	96.27	1	446	2	440	0.0e+00	528.6	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
2904406893	241	18.38	4	85	193	242	7.9e-19	8.2	COG0428	Zinc transporter ZupT	266
2904406893	241	51.84	67	240	126	266	7.9e-19	58.4	COG0428	Zinc transporter ZupT	266
2904406895	259	47.52	35	233	106	220	1.3e-09	32.7	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2904406896	596	98.92	2	567	3	551	0.0e+00	494.4	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2904406897	125	97.58	2	125	3	123	6.3e-59	191.9	COG4288	Uncharacterized protein	124
2904406899	355	89.18	1	246	5	243	2.5e-45	149.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904406900	204	83.25	9	202	8	166	1.4e-20	67.1	COG3065	Starvation-inducible outer membrane lipoprotein	191
2904406902	156	81.18	1	147	35	185	3.3e-36	119.5	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2904406903	411	93.33	2	378	12	375	1.6e-66	219.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904406904	1061	99.7	3	1039	2	1012	0.0e+00	1120	COG0841	Multidrug efflux pump subunit AcrB	1009
2904406905	811	95.82	286	810	20	546	0.0e+00	539	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2904406907	147	16.26	1	39	139	171	3.8e-02	3.6	COG1824	Permease, similar to cation transporters	203
2904406907	147	31.03	57	143	109	171	3.8e-02	8.8	COG1824	Permease, similar to cation transporters	203
2904406908	502	62.94	89	464	139	386	1.4e-63	209.8	COG0642	Signal transduction histidine kinase	336
2904406909	233	89.47	1	163	6	124	2.7e-24	79.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2904406910	1682	64.68	2	388	17	320	2.2e-30	100.1	COG0515	Serine/threonine protein kinase	384
2904406910	1682	72.59	1291	1682	101	386	2.6e-52	173.2	COG0642	Signal transduction histidine kinase	336
2904406911	142	58.4	2	89	13	85	5.7e-13	43.1	COG3293	Transposase	124
2904406914	314	97.87	1	314	7	327	1.1e-103	341	COG0142	Geranylgeranyl pyrophosphate synthase	322
2904406915	184	82.55	3	184	16	190	1.9e-50	165	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
2904406916	715	28.57	580	602	24	37	1.2e-02	3.6	COG1996	DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger	49
2904406916	715	44.9	613	650	20	41	1.2e-02	8.2	COG1996	DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger	49
2904406916	715	89.39	1	538	55	568	0.0e+00	616.9	COG0550	DNA topoisomerase IA	570
2904406917	155	100	5	155	1	157	4.3e-52	170.4	COG2922	Uncharacterized conserved protein Smg, DUF494 family	157
2904406918	371	98.05	9	370	5	356	1.9e-121	399.5	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
2904406920	178	99.41	1	164	1	168	3.6e-64	209.6	COG0242	Peptide deformylase	168
2904406921	307	98.38	1	305	2	304	1.2e-118	390.2	COG0223	Methionyl-tRNA formyltransferase	307
2904406922	431	99.72	90	431	1	357	1.1e-98	325.1	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
2904406924	728	97.61	3	719	13	707	0.0e+00	553.1	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
2904406925	454	97.86	2	454	5	461	0.0e+00	482.3	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904406926	457	98.21	232	454	2	221	2.7e-98	116.3	COG0569	Trk K+ transport system, NAD-binding component	225
2904406926	457	99.11	1	229	1	222	2.7e-98	210.2	COG0569	Trk K+ transport system, NAD-binding component	225
2904406927	195	45.08	10	155	62	171	7.0e-13	42.5	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2904406928	132	91.23	3	132	8	111	1.2e-19	63.8	COG0607	Rhodanese-related sulfurtransferase	110
2904406929	244	33.98	3	237	4	125	1.3e-12	42.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2904406930	606	99.5	1	604	2	601	0.0e+00	1015.6	COG1217	Predicted membrane GTPase involved in stress response	603
2904406932	400	98.54	5	399	3	408	9.1e-99	325.2	COG0004	Ammonia channel protein AmtB	409
2904406933	387	24.72	8	247	33	76	5.9e-04	5.6	COG1633	Rubrerythrin	176
2904406933	387	26.4	255	342	38	84	5.9e-04	9	COG1633	Rubrerythrin	176
2904406934	247	79.65	70	241	14	150	1.4e-05	18.6	COG2406	Protein distantly related to bacterial ferritins	172
2904406935	605	99.32	18	591	4	591	0.0e+00	456.5	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2904406936	894	27.9	388	524	3	127	1.3e-48	64.8	COG1232	Protoporphyrinogen oxidase	444
2904406936	894	54.52	28	369	184	406	5.0e-09	30	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904406936	894	69.87	543	863	135	447	1.3e-48	93.4	COG1232	Protoporphyrinogen oxidase	444
2904406937	591	65.44	5	582	12	560	1.2e-28	91.8	COG3250	Beta-galactosidase/beta-glucuronidase	808
2904406938	359	97.07	38	358	2	332	3.1e-70	230.9	COG1085	Galactose-1-phosphate uridylyltransferase	338
2904406939	357	89.57	4	354	20	371	2.4e-104	343.1	COG0153	Galactokinase	390
2904406940	399	20.73	275	372	346	441	3.1e-11	11.4	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2904406940	399	40.82	35	269	63	251	3.1e-11	18.8	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2904406941	290	81.25	43	176	24	127	5.3e-06	20.5	COG3794	Plastocyanin	128
2904406945	92	98.75	2	80	2	80	2.0e-19	63.9	COG0695	Glutaredoxin	80
2904406947	193	27.78	111	183	28	57	6.8e-06	7.3	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
2904406947	193	45.37	4	90	10	58	6.8e-06	10.9	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
2904406948	203	94.59	2	203	5	214	6.1e-39	127.6	COG2928	Uncharacterized membrane protein	222
2904406949	285	96.91	1	285	7	288	2.2e-81	267.5	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
2904406950	284	65.98	33	201	46	173	2.3e-24	79.6	COG1525	Endonuclease YncB, thermonuclease family	192
2904406951	531	97.95	1	527	3	528	0.0e+00	436.3	COG0578	Glycerol-3-phosphate dehydrogenase	532
2904406952	245	57.6	24	115	46	117	1.2e-25	30.2	COG3293	Transposase	124
2904406952	245	97.6	109	237	2	123	1.2e-25	55.2	COG3293	Transposase	124
2904406961	1008	64.95	209	784	49	287	1.6e-09	9.2	COG0457	Tetratricopeptide (TPR) repeat	291
2904406961	1008	67.57	2	126	11	110	3.3e-24	78.2	COG3710	DNA-binding winged helix-turn-helix (wHTH) domain	148
2904406961	1008	74.46	657	985	63	336	1.6e-09	28.2	COG0457	Tetratricopeptide (TPR) repeat	291
2904406962	299	98.84	10	281	3	257	1.9e-81	267	COG0688	Phosphatidylserine decarboxylase	239
2904406963	368	93.73	1	365	24	382	2.9e-129	425.6	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
2904406964	319	91	19	317	20	292	1.6e-67	221.9	COG4240	Pantothenate kinase-related protein Tda10 (topoisomerase I damage affected protein)	300
2904406965	323	99.08	2	323	2	325	8.6e-109	357.6	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2904406966	394	97.65	1	386	7	380	2.4e-119	392.9	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
2904406967	223	96.12	1	223	9	231	1.4e-49	162.9	COG0670	Integral membrane protein, interacts with FtsH	233
2904406968	345	96.06	6	345	3	343	1.4e-80	265	COG1363	Putative aminopeptidase FrvX	355
2904406969	328	98.58	47	327	4	280	3.6e-39	129.2	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
2904406970	166	92.36	24	166	8	152	2.7e-13	44.1	COG1225	Peroxiredoxin	157
2904406971	140	94.63	1	140	9	149	2.9e-54	177.8	COG1981	Uncharacterized membrane protein	149
2904406972	241	96.68	6	240	1	233	7.9e-60	196.3	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
2904406973	172	98.09	7	171	2	155	2.0e-52	171.7	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
2904406974	219	96.63	1	205	1	201	9.6e-61	199.4	COG0288	Carbonic anhydrase	207
2904406975	78	12.08	1	78	483	550	1.4e-05	18.1	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2904406977	114	65.64	1	112	30	136	2.2e-32	106.1	COG3436	Transposase	157
2904406978	132	50.43	8	119	6	64	2.1e-17	57.9	COG2963	Transposase and inactivated derivatives	116
2904406981	289	95.15	10	269	5	259	3.9e-58	191.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904406982	384	66.5	9	384	127	388	1.4e-70	233	COG0642	Signal transduction histidine kinase	336
2904406983	202	53.12	1	192	157	343	1.0e-44	147.3	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2904406984	272	98.52	7	272	2	267	5.5e-59	193.8	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2904406985	1036	49.57	911	1035	2	116	1.9e-65	102.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904406985	1036	51.72	643	764	2	121	1.9e-65	63.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904406985	1036	53.02	765	907	2	124	1.9e-65	60	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904406985	1036	78.68	194	592	79	388	8.1e-80	263.6	COG0642	Signal transduction histidine kinase	336
2904406986	241	95.75	5	215	4	206	5.0e-65	213.2	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
2904406989	310	90.31	14	285	20	280	1.9e-91	300.4	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2904406990	274	98.88	10	267	3	267	3.6e-75	247.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904406991	175	99.26	1	148	1	135	1.7e-38	126	COG1943	REP element-mobilizing transposase RayT	136
2904406992	632	31.45	1	215	32	204	0.0e+00	11.5	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2904406992	632	66	279	631	185	547	0.0e+00	480.2	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2904406994	394	73.14	11	210	64	240	8.1e-15	48.1	COG2202	PAS domain	232
2904406994	394	95.08	198	376	7	180	1.4e-54	178.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904406995	594	27.62	5	150	5	133	0.0e+00	74.5	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904406995	594	70.66	247	594	134	463	0.0e+00	425.1	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904406996	886	60	759	880	15	89	9.4e-10	32.3	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2904406996	886	85.53	54	473	56	392	6.9e-83	273.7	COG0642	Signal transduction histidine kinase	336
2904406996	886	93.23	629	758	6	129	8.0e-69	133.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2904406996	886	95.49	481	614	5	131	8.0e-69	90.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2904407000	308	80.34	11	308	30	262	3.1e-13	42.5	COG0382	4-hydroxybenzoate polyprenyltransferase	289
2904407001	279	97.53	2	278	8	283	5.9e-95	312.1	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2904407002	301	96.64	12	300	4	291	1.1e-100	331	COG1175	ABC-type sugar transport system, permease component	295
2904407003	424	97.29	1	406	8	438	3.1e-59	195.8	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2904407005	517	69.04	165	501	119	390	1.4e-66	220	COG0642	Signal transduction histidine kinase	336
2904407006	92	65.87	1	89	42	124	3.8e-24	79.8	COG3245	Cytochrome c5	126
2904407007	893	42.56	18	140	122	224	6.6e-99	52.8	COG2202	PAS domain	232
2904407007	893	50	269	393	121	241	6.6e-99	79.3	COG2202	PAS domain	232
2904407007	893	50.41	138	271	121	242	6.6e-99	69.7	COG2202	PAS domain	232
2904407007	893	57.85	512	645	103	242	6.6e-99	75.7	COG2202	PAS domain	232
2904407007	893	58.26	383	520	102	242	6.6e-99	78	COG2202	PAS domain	232
2904407007	893	67.66	635	893	119	367	9.3e-68	222.5	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2904407009	231	77.24	1	226	7	213	1.1e-45	150.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904407010	206	97.05	1	206	1	230	1.1e-46	153	COG3416	Uncharacterized protein	233
2904407012	201	30.49	33	178	55	104	1.0e-06	21.6	COG2010	Cytochrome c, mono- and diheme variants	150
2904407013	492	64.57	5	472	249	711	4.4e-93	306.8	COG3256	Nitric oxide reductase large subunit	717
2904407015	86	10.95	3	78	236	288	5.0e-07	23.7	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904407016	396	87.03	1	390	41	342	1.4e-100	330.9	COG2951	Membrane-bound lytic murein transglycosylase B	343
2904407017	193	96.59	1	192	2	199	1.6e-84	277.1	COG0605	Superoxide dismutase	204
2904407018	153	91.24	19	152	6	130	4.3e-14	46.8	COG4319	Ketosteroid isomerase homolog	137
2904407019	307	98.67	2	299	2	298	1.3e-71	236.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904407020	157	99.36	1	157	1	155	6.5e-62	202.4	COG2954	CYTH domain, found in class IV adenylate cyclase and various triphosphatases	156
2904407021	185	71.92	31	148	7	111	2.2e-05	15.8	COG3427	Carbon monoxide dehydrogenase subunit G	146
2904407024	464	90	1	461	2	451	2.1e-68	225.3	COG0591	Na+/proline symporter	493
2904407025	201	67.83	11	194	67	222	2.7e-14	45.4	COG1266	Membrane protease YdiL, CAAX protease family	226
2904407026	376	97.01	5	375	5	296	1.5e-70	231.7	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2904407027	722	99.06	4	722	4	741	0.0e+00	564.7	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2904407028	153	96.15	1	152	4	153	5.5e-66	215.4	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2904407029	206	96.5	5	204	3	195	2.9e-43	142.3	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
2904407030	168	99.34	15	164	1	151	6.8e-51	166.5	COG0782	Transcription elongation factor, GreA/GreB family	151
2904407032	99	94.74	1	96	4	93	1.9e-33	108.6	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
2904407033	198	96.2	1	181	7	183	3.5e-50	164.9	COG2840	DNA-nicking endonuclease, Smr domain	184
2904407034	409	97.04	39	404	9	369	1.7e-90	297.6	COG2843	Poly-gamma-glutamate biosynthesis protein CapA/YwtB (capsule formation), metallophosphatase superfamily	372
2904407035	517	92.29	3	419	3	397	3.3e-108	356.7	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
2904407037	344	94.07	18	337	13	266	1.2e-52	173.1	COG1360	Flagellar motor protein MotB	244
2904407038	266	82.02	8	258	30	248	4.4e-40	131.4	COG1291	Flagellar motor component MotA	266
2904407040	274	44.79	6	173	96	181	7.3e-19	61.6	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
2904407041	257	71.23	1	224	84	291	1.6e-59	195.7	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2904407042	304	91.07	15	303	23	287	2.1e-87	287	COG0676	D-hexose-6-phosphate mutarotase	287
2904407043	143	92.16	1	143	8	148	4.6e-61	199.4	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
2904407044	403	98.77	2	395	3	404	4.0e-95	312.9	COG0303	Molybdopterin biosynthesis enzyme	404
2904407045	648	90.58	436	647	4	205	1.4e-46	152.4	COG1910	Periplasmic molybdate-binding protein/domain	223
2904407045	648	97.05	14	429	10	404	4.2e-126	414.9	COG0303	Molybdopterin biosynthesis enzyme	404
2904407046	303	77.14	2	63	10	63	8.0e-04	12.9	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2904407046	303	98.21	78	302	2	220	2.1e-44	145.5	COG1910	Periplasmic molybdate-binding protein/domain	223
2904407049	514	32.39	97	258	36	173	2.4e-20	19	COG3746	Phosphate-selective porin	426
2904407049	514	32.86	325	514	287	426	2.4e-20	47.9	COG3746	Phosphate-selective porin	426
2904407050	260	95.51	1	253	9	263	7.6e-58	190	COG0725	ABC-type molybdate transport system, periplasmic component	258
2904407051	78	21.62	18	78	10	65	3.6e-05	17.5	COG0730	Uncharacterized membrane protein YfcA	258
2904407052	254	92.13	4	254	18	263	1.8e-41	136.3	COG0725	ABC-type molybdate transport system, periplasmic component	258
2904407053	137	91.3	1	63	7	69	3.8e-23	11.9	COG3585	Molybdopterin-binding protein	69
2904407053	137	94.2	66	133	3	67	3.8e-23	63.3	COG3585	Molybdopterin-binding protein	69
2904407054	223	96	1	221	4	219	2.0e-79	260.3	COG4149	ABC-type molybdate transport system, permease component	225
2904407055	302	68.29	1	297	14	252	2.3e-78	258.2	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
2904407056	270	87.02	18	137	18	131	1.9e-32	105.9	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
2904407056	270	97.1	201	269	2	68	1.9e-43	81.2	COG3585	Molybdopterin-binding protein	69
2904407056	270	98.55	129	197	2	69	1.9e-43	64.3	COG3585	Molybdopterin-binding protein	69
2904407057	113	83.05	1	102	15	112	6.1e-13	43.6	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2904407058	171	87.16	4	138	2	130	7.8e-28	91.6	COG0394	Protein-tyrosine-phosphatase	139
2904407060	141	18.49	1	113	1	27	6.4e-05	17.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2904407061	163	97.3	4	141	4	147	1.0e-27	89.5	COG0394	Protein-tyrosine-phosphatase	139
2904407062	385	97.96	20	369	5	340	2.1e-115	379.4	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
2904407064	560	88.6	459	558	6	106	3.7e-20	64.9	COG0607	Rhodanese-related sulfurtransferase	110
2904407064	560	100	8	441	1	430	5.5e-93	306.8	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2904407065	243	97.6	1	243	2	245	4.9e-89	291.1	COG4422	Bacteriophage protein gp37	250
2904407068	190	93.1	4	190	14	202	1.3e-36	119.6	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2904407072	171	90.51	18	169	13	155	5.8e-28	92.4	COG1719	Predicted hydrocarbon binding protein, contains 4VR domain	158
2904407073	120	88.75	7	97	5	75	8.0e-16	50.7	COG5645	Uncharacterized conserved protein YceK	80
2904407074	325	98.05	20	325	3	304	1.8e-41	136.6	COG0223	Methionyl-tRNA formyltransferase	307
2904407075	242	95.37	2	242	10	256	9.4e-11	35.6	COG0730	Uncharacterized membrane protein YfcA	258
2904407076	236	76.19	123	230	29	124	4.1e-36	8.7	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
2904407076	236	99.21	1	126	1	125	4.1e-36	116.5	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
2904407077	104	88.07	1	103	4	99	1.2e-18	61.4	COG1993	PII-like signaling protein	109
2904407079	162	90.07	27	161	3	129	1.0e-43	142.4	COG5478	Low affinity Fe/Cu permease	141
2904407080	229	91.15	4	227	14	219	1.1e-76	251.3	COG1136	ABC-type lipoprotein export system, ATPase component	226
2904407081	414	99.27	1	413	3	409	1.3e-92	304.7	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2904407082	339	92.56	1	333	11	371	4.3e-50	165.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904407085	350	92.22	3	349	16	347	6.9e-71	233.2	COG0628	Predicted PurR-regulated permease PerM	355
2904407086	391	84.14	3	254	44	287	1.2e-78	258.3	COG1398	Fatty-acid desaturase	289
2904407087	77	78.05	4	77	17	80	4.4e-13	43.5	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
2904407088	144	89.44	2	141	7	133	7.6e-11	36.3	COG3431	Uncharacterized membrane protein, DUF373 family	142
2904407089	1248	19.89	1118	1207	3	72	4.7e-57	14.5	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2904407089	1248	53.12	1	188	158	344	4.7e-57	171.3	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2904407089	1248	78.43	767	1102	83	391	1.4e-68	226.7	COG0642	Signal transduction histidine kinase	336
2904407089	1248	98.52	206	470	3	268	1.6e-80	263.7	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2904407090	321	66.48	3	161	2	122	6.9e-14	46.2	COG1286	Uncharacterized membrane protein, required for colicin V production	182
2904407092	113	98.21	2	113	2	111	1.3e-43	141.9	COG2824	Uncharacterized Zn-ribbon-containing protein	112
2904407093	144	92.47	2	137	7	141	8.5e-38	123.7	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2904407094	367	97.33	14	359	1	364	1.0e-104	344.9	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2904407095	127	87.12	1	126	10	124	1.4e-36	119.4	COG2343	Uncharacterized conserved protein, DUF427 family	132
2904407096	127	99.32	3	120	2	146	1.5e-13	43.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2904407097	543	73.1	146	537	101	388	9.4e-68	222.8	COG0642	Signal transduction histidine kinase	336
2904407100	834	77.78	605	833	35	237	1.4e-23	76.9	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2904407100	834	92.01	7	583	15	578	2.3e-105	333.2	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2904407101	463	99.55	1	440	2	444	0.0e+00	559.5	COG1160	Predicted GTPases	444
2904407102	423	27.02	282	401	75	181	1.2e-45	19.8	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
2904407102	423	63.38	19	283	42	292	1.2e-45	132.4	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
2904407103	211	96.63	1	204	6	206	1.7e-52	172.4	COG2976	Putative negative regulator of RcsB-dependent stress response	207
2904407104	422	98.38	1	422	1	425	0.0e+00	438.9	COG0124	Histidyl-tRNA synthetase	429
2904407105	256	96.4	1	251	4	244	4.2e-62	204	COG3063	Tfp pilus assembly protein PilF	250
2904407106	366	100	13	357	1	349	0.0e+00	480.8	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
2904407107	143	98.52	2	136	2	134	7.6e-65	211.1	COG0105	Nucleoside diphosphate kinase	135
2904407110	1479	8.88	545	632	15	90	2.5e-95	24.8	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904407110	1479	13.79	565	696	12	129	2.5e-95	49.4	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904407110	1479	50.35	154	561	111	541	2.5e-95	112.5	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904407110	1479	77.34	694	1459	52	713	2.5e-95	157	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904407112	107	98.18	1	107	3	110	1.3e-39	128.9	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2904407113	386	97.15	1	377	2	376	0.0e+00	458.6	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
2904407114	162	90.67	1	147	2	137	3.5e-49	160.9	COG1959	DNA-binding transcriptional regulator, IscR family	150
2904407115	1215	92.39	707	1215	2	523	0.0e+00	685.6	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
2904407115	1215	99.56	4	689	2	677	0.0e+00	787.3	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2904407116	199	88.78	1	196	17	198	3.9e-58	190.6	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2904407117	65	81.43	1	65	1	57	1.6e-22	73.6	COG5428	Uncharacterized protein YuzE	69
2904407121	994	22.68	31	189	326	452	1.4e-28	28.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
2904407121	994	28.93	163	332	294	455	1.4e-28	43.7	COG2931	Ca2+-binding protein, RTX toxin-related	510
2904407121	994	39.82	326	543	231	453	1.4e-28	18.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2904407121	994	49.11	540	969	176	450	1.4e-28	17.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2904407122	589	96.55	7	583	9	568	0.0e+00	758.8	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2904407123	440	96.15	7	431	15	389	4.0e-39	129	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904407124	447	87.61	10	439	45	447	5.4e-67	220.4	COG1538	Outer membrane protein TolC	457
2904407125	204	95.9	1	196	6	192	8.8e-80	261.2	COG0194	Guanylate kinase	191
2904407126	128	71.32	9	128	21	117	9.4e-09	22.7	COG3474	Cytochrome c2	135
2904407127	284	90.11	1	269	18	272	5.5e-11	36	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904407128	568	75.16	2	568	152	732	2.8e-109	358.8	COG4993	Glucose dehydrogenase	773
2904407132	295	37.8	19	295	417	670	5.4e-40	132	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
2904407133	289	100	1	289	1	290	3.3e-96	316.6	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
2904407134	308	65.32	9	308	3	309	1.5e-38	127.5	COG0515	Serine/threonine protein kinase	384
2904407135	146	88.27	2	146	7	149	2.5e-35	115.9	COG3160	Regulator of sigma D	162
2904407136	184	93.15	29	166	4	139	8.4e-27	88.1	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2904407137	291	98.64	1	290	1	290	0.0e+00	433.4	COG0074	Succinyl-CoA synthetase, alpha subunit	293
2904407138	386	99.48	1	386	1	381	0.0e+00	528.4	COG0045	Succinyl-CoA synthetase, beta subunit	387
2904407139	539	81.98	65	536	64	386	3.9e-44	144.8	COG0642	Signal transduction histidine kinase	336
2904407140	476	97.43	1	476	6	460	0.0e+00	552	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904407142	600	99.66	15	587	2	591	0.0e+00	564.6	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2904407143	438	83.68	2	436	52	410	2.1e-28	92.1	COG3307	O-antigen ligase	424
2904407144	359	87.29	4	356	44	400	3.9e-27	90.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904407145	365	95.84	1	360	15	406	7.0e-47	155.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904407146	352	99.12	8	352	2	338	1.7e-68	225.7	COG0859	ADP-heptose:LPS heptosyltransferase	334
2904407147	360	73.35	11	358	108	407	1.5e-37	124.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904407149	381	95.6	5	369	12	402	2.7e-41	136.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904407150	373	79.95	8	372	76	402	8.7e-38	125.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904407151	372	96.09	5	369	8	400	4.1e-41	135.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904407152	238	89.73	17	228	14	214	1.9e-21	70.6	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
2904407153	321	95.43	2	321	16	328	5.5e-75	246.4	COG0598	Mg2+ and Co2+ transporter CorA	322
2904407154	312	49.58	1	310	4	181	2.2e-32	107.6	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2904407155	323	95.85	7	310	5	304	4.1e-38	125.3	COG1216	Glycosyltransferase, GT2 family	305
2904407156	388	58.74	85	378	156	407	5.4e-10	33.2	COG3307	O-antigen ligase	424
2904407158	859	99.63	5	859	1	802	0.0e+00	1161.6	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2904407159	462	93.58	3	453	24	460	8.6e-109	358.4	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904407160	230	75.22	1	221	7	176	1.0e-51	170.2	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
2904407162	788	96.28	1	784	13	762	0.0e+00	474.4	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
2904407163	242	96.54	1	237	8	230	6.3e-96	314.4	COG0689	Ribonuclease PH	230
2904407164	41	20.19	1	41	160	201	3.1e-04	15	COG0288	Carbonic anhydrase	207
2904407165	40	19.66	3	40	5	27	4.3e-06	21.5	COG2963	Transposase and inactivated derivatives	116
2904407166	174	84	3	173	8	175	6.6e-21	68.7	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
2904407167	321	93.61	1	304	2	294	3.2e-53	175.1	COG1216	Glycosyltransferase, GT2 family	305
2904407168	221	84.91	1	200	5	184	7.7e-32	103.9	COG0560	Phosphoserine phosphatase	212
2904407169	251	92.83	3	250	9	254	2.5e-38	125.8	COG0300	Short-chain dehydrogenase	265
2904407170	432	83.58	18	428	59	450	1.5e-39	130.2	COG0277	FAD/FMN-containing dehydrogenase	459
2904407171	320	92.9	6	317	14	314	2.6e-27	90.1	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2904407172	288	95.52	1	287	13	289	2.9e-43	142.2	COG0382	4-hydroxybenzoate polyprenyltransferase	289
2904407173	314	71.72	6	313	12	290	8.5e-31	101.2	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2904407174	316	98.44	1	315	3	318	3.0e-76	251.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2904407176	582	92.67	1	447	3	381	5.3e-36	119	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904407177	279	46.01	1	235	83	226	9.9e-12	38.6	COG1216	Glycosyltransferase, GT2 family	305
2904407178	624	43.85	260	494	59	165	3.6e-38	84.3	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2904407178	624	44.67	65	236	56	164	3.6e-38	38.8	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2904407179	424	96.02	25	268	2	242	3.4e-91	299.3	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
2904407180	272	97.74	5	272	7	265	3.4e-71	233.8	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2904407181	596	85.62	1	307	3	270	9.4e-68	222.5	COG1216	Glycosyltransferase, GT2 family	305
2904407181	596	93.15	315	596	3	301	4.3e-24	74.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2904407182	47	24.11	2	45	102	135	1.4e-05	20.4	COG1848	Predicted nucleic acid-binding protein, contains PIN domain	140
2904407184	89	96.77	1	87	2	91	2.4e-26	86	COG2929	Uncharacterized conserved protein, DUF497 family	93
2904407185	88	55.32	1	80	58	135	7.6e-07	24.3	COG1848	Predicted nucleic acid-binding protein, contains PIN domain	140
2904407187	76	88.61	1	73	9	78	3.6e-30	97.7	COG2442	Uncharacterized conserved protein, DUF433 family	79
2904407188	123	100	1	114	1	113	8.6e-38	123.1	COG4634	Predicted nuclease, contains PIN domain, potential toxin-antitoxin system component	113
2904407189	456	98.05	1	454	9	460	0.0e+00	495.5	COG0773	UDP-N-acetylmuramate-alanine ligase	459
2904407190	170	57.58	6	168	75	264	1.3e-24	81.6	COG0666	Ankyrin repeat	235
2904407191	125	98.41	1	125	3	126	3.1e-56	183.1	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
2904407192	275	96.84	69	259	2	154	7.9e-17	55.7	COG0639	Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family	155
2904407193	335	90.28	1	334	23	347	1.1e-64	212.9	COG0628	Predicted PurR-regulated permease PerM	355
2904407194	279	80.28	4	262	6	237	2.3e-52	171.7	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
2904407195	323	87.01	12	313	7	274	1.9e-64	212.3	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
2904407196	296	95.51	1	296	9	306	7.7e-77	253	COG0501	Zn-dependent protease with chaperone function	302
2904407197	372	83.54	10	372	66	410	1.1e-96	318.5	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2904407198	246	50.63	14	213	50	170	4.0e-21	69.2	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2904407199	459	98.25	6	459	5	452	0.0e+00	639.7	COG1066	Predicted ATP-dependent serine protease	456
2904407201	243	51.25	3	226	54	196	1.8e-11	38.9	COG0500	SAM-dependent methyltransferase	257
2904407202	78	12.47	1	70	83	131	2.2e-09	30.8	COG5659	SRSO17 transposase	385
2904407204	206	17.54	154	202	118	154	1.3e-14	4.4	COG1716	Forkhead associated (FHA) domain, binds pSer, pThr, pTyr	191
2904407204	206	38.86	5	150	91	172	1.3e-14	42.9	COG1716	Forkhead associated (FHA) domain, binds pSer, pThr, pTyr	191
2904407205	434	85.44	11	433	65	463	0.0e+00	461.9	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904407206	405	84.77	4	386	56	389	2.4e-55	181.9	COG0642	Signal transduction histidine kinase	336
2904407207	447	98.07	1	444	1	458	0.0e+00	533.4	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904407208	103	89.62	1	103	11	105	6.1e-30	98.1	COG1677	Flagellar hook-basal body complex protein FliE	105
2904407209	568	97.26	16	567	14	546	0.0e+00	538.1	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
2904407210	335	97.94	1	335	8	340	4.7e-117	385.3	COG1536	Flagellar motor switch protein FliG	339
2904407211	235	90.95	2	234	14	234	1.3e-45	150.1	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
2904407212	453	98.64	10	451	5	440	0.0e+00	617.3	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
2904407213	151	95.27	1	144	1	141	4.4e-20	66.4	COG2882	Flagellar biosynthesis chaperone FliJ	148
2904407214	457	30.59	30	451	279	412	4.7e-30	97.5	COG3144	Flagellar hook-length control protein FliK	417
2904407215	136	96.43	2	112	1	108	5.3e-41	133.2	COG0360	Ribosomal protein S6	112
2904407216	75	83.54	1	68	14	79	7.9e-32	103.1	COG0238	Ribosomal protein S18	75
2904407218	148	99.32	1	148	1	147	3.3e-53	174.1	COG0359	Ribosomal protein L9	148
2904407219	422	98.8	1	419	2	414	0.0e+00	458.8	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
2904407220	920	64.1	383	920	214	638	3.5e-101	333.5	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2904407221	487	90.7	358	483	12	128	2.5e-42	137.3	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2904407221	487	99.7	4	348	2	335	8.1e-122	400.8	COG0836	Mannose-1-phosphate guanylyltransferase	333
2904407222	354	97.58	1	354	10	372	0.0e+00	485.8	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
2904407223	54	27.88	1	52	52	80	5.7e-05	17.6	COG2944	DNA-binding transcriptional regulator YiaG, XRE-type HTH domain	104
2904407225	108	16.71	7	107	40	111	5.0e-04	13.1	COG0172	Seryl-tRNA synthetase	429
2904407226	254	95.36	5	252	5	230	1.5e-62	205.5	COG3219	Uncharacterized protein	237
2904407227	281	97.16	4	281	3	276	4.3e-109	358.3	COG3220	Uncharacterized conserved protein, UPF0276 family	282
2904407228	107	88.42	1	101	6	89	7.5e-10	33.2	COG3767	Uncharacterized low-complexity protein	95
2904407230	257	90.98	2	174	7	127	2.1e-32	105.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2904407231	181	97.83	1	181	1	180	2.0e-88	289	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
2904407232	405	88.78	51	405	29	305	1.0e-46	153.8	COG0501	Zn-dependent protease with chaperone function	302
2904407233	242	76.82	1	242	65	296	6.8e-77	252.8	COG1162	Putative ribosome biogenesis GTPase RsgA	301
2904407234	341	91.9	19	340	30	358	1.5e-56	184.7	COG5345	Uncharacterized protein	358
2904407235	307	98.66	1	300	5	299	3.2e-119	392	COG4973	Site-specific recombinase XerC	299
2904407236	237	97.71	14	234	2	214	7.0e-52	170.5	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
2904407237	276	99.26	3	276	2	270	4.7e-102	335.3	COG0253	Diaminopimelate epimerase	272
2904407238	415	98.99	1	390	5	395	0.0e+00	471.9	COG0019	Diaminopimelate decarboxylase	394
2904407239	349	97.46	1	346	8	352	2.5e-116	383.4	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
2904407240	90	98.89	1	90	1	89	6.4e-33	107	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
2904407241	333	77.69	9	250	54	241	3.9e-35	116.3	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2904407242	308	99.01	1	303	1	300	1.4e-112	370.1	COG2974	DNA recombination-dependent growth factor C	303
2904407243	808	15.06	20	187	26	120	1.2e-128	1.5	COG1067	Predicted ATP-dependent protease	647
2904407243	808	69.1	185	794	173	608	1.2e-128	420.5	COG1067	Predicted ATP-dependent protease	647
2904407252	253	98.56	47	253	3	207	1.7e-64	211.3	COG3404	Formiminotetrahydrofolate cyclodeaminase	208
2904407254	242	14.92	1	40	5	41	7.1e-09	4	COG2129	Predicted phosphoesterase, related to the Icc protein	226
2904407254	242	26.21	34	226	159	223	7.1e-09	22.2	COG2129	Predicted phosphoesterase, related to the Icc protein	226
2904407255	412	98.38	2	407	2	365	0.0e+00	448.8	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
2904407256	274	98.13	1	268	2	264	2.3e-95	313.1	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
2904407257	858	99.88	1	854	1	851	0.0e+00	1510.5	COG1049	Aconitase B	852
2904407258	308	90.2	1	308	4	316	1.6e-105	347.2	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2904407259	444	99.76	1	425	1	417	0.0e+00	547.5	COG1004	UDP-glucose 6-dehydrogenase	414
2904407260	394	98.24	5	394	5	394	0.0e+00	459.8	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2904407261	502	99.15	1	483	4	469	0.0e+00	642.1	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
2904407262	166	87.36	4	166	2	160	4.2e-40	131.9	COG1286	Uncharacterized membrane protein, required for colicin V production	182
2904407263	364	66.81	1	207	1	159	8.1e-32	36.7	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
2904407263	364	79.41	157	364	50	238	8.1e-32	68.4	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
2904407264	420	97.67	1	420	3	421	0.0e+00	432.1	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
2904407265	266	78.57	1	238	56	286	1.7e-108	356.4	COG0777	Acetyl-CoA carboxylase beta subunit	294
2904407266	269	98.87	1	267	2	263	1.9e-96	316.5	COG0159	Tryptophan synthase alpha chain	265
2904407267	406	97.73	12	405	3	389	0.0e+00	674.5	COG0133	Tryptophan synthase beta chain	396
2904407268	219	99.04	9	212	2	208	1.2e-69	228.6	COG0135	Phosphoribosylanthranilate isomerase	208
2904407269	271	93.26	1	257	3	251	2.6e-85	280.2	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
2904407270	429	99.24	25	429	4	396	0.0e+00	479.2	COG0372	Citrate synthase	390
2904407272	632	66.67	548	629	15	68	6.6e-03	8.9	COG1722	Exonuclease VII small subunit	81
2904407272	632	99.44	1	532	1	532	0.0e+00	578.2	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2904407273	111	14.08	4	107	344	423	7.7e-06	19.3	COG2303	Choline dehydrogenase or related flavoprotein	542
2904407275	43	7.39	1	43	517	558	2.2e-16	54.3	COG2303	Choline dehydrogenase or related flavoprotein	542
2904407277	477	98.21	18	397	5	333	2.1e-70	231.1	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2904407278	330	17.44	21	85	12	56	7.6e-56	15.7	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2904407278	330	75.97	104	330	57	252	7.6e-56	169.3	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2904407279	576	97.21	24	283	3	246	0.0e+00	286.7	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2904407279	576	97.21	319	575	3	246	0.0e+00	289	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2904407280	279	95.47	1	267	5	257	3.7e-49	161.2	COG2116	Formate/nitrite transporter FocA, FNT family	265
2904407281	579	65.53	240	570	2	309	9.6e-44	144.1	COG0515	Serine/threonine protein kinase	384
2904407281	579	96.69	1	256	3	265	6.6e-36	115.6	COG0631	Serine/threonine protein phosphatase PrpC	262
2904407282	163	96.69	16	163	6	151	5.9e-52	169.9	COG1513	Cyanate lyase	151
2904407284	272	98.64	1	271	3	293	5.9e-37	122.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904407286	424	95.95	2	423	6	408	2.3e-102	337	COG2223	Nitrate/nitrite transporter NarK	417
2904407287	573	91.91	5	248	11	260	8.5e-45	145.3	COG0631	Serine/threonine protein phosphatase PrpC	262
2904407288	812	99.38	1	808	1	796	0.0e+00	1180.9	COG1251	NAD(P)H-nitrite reductase, large subunit	793
2904407289	106	98.13	1	103	2	106	4.4e-27	88.4	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2904407290	908	76.19	858	908	3	50	4.1e-08	26.7	COG2906	Bacterioferritin-associated ferredoxin	63
2904407290	908	94.32	3	715	45	808	0.0e+00	601.6	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2904407291	441	93.13	2	348	21	332	1.1e-85	281.9	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2904407292	192	97.42	1	191	4	192	7.8e-64	209	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
2904407294	466	100	1	464	1	470	0.0e+00	719.1	COG1282	NAD/NADP transhydrogenase beta subunit	463
2904407295	520	27.82	416	520	100	200	0.0e+00	64.8	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2904407295	520	100	2	372	1	363	0.0e+00	521.5	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2904407296	246	95.9	1	246	9	242	3.7e-86	282.6	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2904407297	162	92.07	1	159	5	155	1.5e-71	233.5	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
2904407298	376	97.07	7	376	2	366	0.0e+00	450.2	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
2904407299	717	98.84	2	601	7	601	0.0e+00	776.1	COG0514	Superfamily II DNA helicase RecQ	590
2904407300	379	67.11	115	378	86	287	1.8e-05	18.3	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
2904407300	379	72.65	9	114	19	103	2.0e-13	43.7	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2904407301	920	59.09	7	374	100	242	1.2e-14	49	COG2202	PAS domain	232
2904407301	920	72.28	362	634	101	366	5.3e-51	167.3	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2904407303	149	83.67	6	138	15	137	3.8e-20	66.3	COG3151	Uncharacterized protein YqiB, DUF1249 family	147
2904407304	98	52.63	1	98	41	120	1.3e-12	42.5	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
2904407306	338	99.05	1	315	4	317	7.7e-94	308.8	COG0180	Tryptophanyl-tRNA synthetase	314
2904407308	339	40.2	1	335	5	326	3.0e-57	188.5	COG1251	NAD(P)H-nitrite reductase, large subunit	793
2904407310	314	98.52	8	273	4	269	4.0e-64	211.3	COG1360	Flagellar motor protein MotB	244
2904407311	284	98.13	1	284	3	264	1.3e-87	287.4	COG1291	Flagellar motor component MotA	266
2904407312	633	99.04	4	632	4	623	0.0e+00	865.8	COG0326	Molecular chaperone, HSP90 family	623
2904407313	126	96.77	1	126	3	122	1.6e-40	132.6	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
2904407315	109	96.91	10	104	2	95	4.2e-25	81.8	COG5626	Uncharacterized protein	97
2904407317	386	60.64	102	385	76	377	4.9e-18	56.6	COG2319	WD40 repeat	466
2904407318	1149	11.92	1	241	12	170	2.4e-124	51.5	COG2911	Autotransporter translocation and assembly factor TamB	1278
2904407318	1149	61.92	269	1148	506	1331	2.4e-124	359.8	COG2911	Autotransporter translocation and assembly factor TamB	1278
2904407319	572	96.02	3	572	25	603	1.6e-107	354.9	COG0729	Outer membrane translocation and assembly module TamA	594
2904407320	153	33.57	40	153	186	281	1.2e-25	84.9	COG1652	Nucleoid-associated protein YgaU, contains BON and LysM domains	269
2904407321	744	91.14	2	743	10	750	0.0e+00	820.2	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
2904407322	347	99.42	1	343	2	343	0.0e+00	513.4	COG0418	Dihydroorotase	344
2904407330	858	7.61	775	813	301	327	5.6e-06	2.5	COG3299	Uncharacterized phage protein gp47/JayE	353
2904407330	858	17.18	180	281	14	74	5.6e-06	2.1	COG3299	Uncharacterized phage protein gp47/JayE	353
2904407330	858	23.94	601	729	130	214	5.6e-06	13.6	COG3299	Uncharacterized phage protein gp47/JayE	353
2904407331	121	80.17	4	116	16	108	4.6e-15	49.4	COG3628	Phage baseplate assembly protein W	116
2904407333	171	18.86	25	170	428	536	1.0e-10	35.1	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2904407335	121	11.89	20	110	230	263	2.6e-05	18.5	COG1652	Nucleoid-associated protein YgaU, contains BON and LysM domains	269
2904407341	641	13.97	428	462	5	29	7.4e-04	7.1	COG1102	Cytidylate kinase	179
2904407341	641	17.88	195	317	3	34	7.4e-04	4.1	COG1102	Cytidylate kinase	179
2904407344	237	20.41	165	182	24	33	4.0e-03	5.2	COG1996	DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger	49
2904407344	237	22.45	63	82	23	33	4.0e-03	3.7	COG1996	DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger	49
2904407346	520	96.37	1	517	6	456	2.4e-45	148.5	COG3497	Phage tail sheath protein FI	394
2904407348	354	96.98	1	349	5	325	2.5e-32	106.6	COG0620	Methionine synthase II (cobalamin-independent)	330
2904407350	164	78.03	12	145	2	104	3.5e-22	73.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
2904407351	941	77.16	522	932	88	391	5.1e-72	238	COG0642	Signal transduction histidine kinase	336
2904407351	941	93.57	1	301	13	303	2.9e-55	181.6	COG3447	Integral membrane sensor domain MASE1	308
2904407356	252	96.62	1	220	6	234	7.7e-38	124.5	COG0412	Dienelactone hydrolase	236
2904407359	125	35.41	1	123	26	133	3.2e-19	64	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2904407360	103	93.46	1	102	7	106	2.8e-20	66.5	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2904407361	377	88.35	15	370	48	411	2.8e-101	333.4	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
2904407363	548	98.39	4	547	5	553	0.0e+00	479.5	COG3961	TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase	557
2904407364	454	94.11	8	454	7	469	2.0e-63	208.9	COG0531	Amino acid transporter	466
2904407365	482	78.55	1	286	25	262	3.8e-45	148.2	COG3452	Extracellular (periplasmic) sensor domain CHASE (specificity unknown)	297
2904407365	482	93.99	297	481	5	176	4.2e-49	160.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904407366	1138	92.65	2	817	55	949	0.0e+00	516.9	COG0474	Magnesium-transporting ATPase (P-type)	917
2904407366	1138	93.77	838	1135	10	295	1.6e-83	274.9	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2904407367	213	59.49	28	208	66	181	3.0e-16	53.6	COG3861	Stress response protein YsnF (function unknown)	195
2904407368	363	65.64	76	277	57	184	4.2e-16	52.8	COG3861	Stress response protein YsnF (function unknown)	195
2904407369	716	94.07	1	712	45	806	0.0e+00	491.2	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2904407370	225	57.85	4	212	8	195	3.3e-21	66.7	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2904407371	198	89	1	193	10	195	6.9e-24	79.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904407372	620	68.04	53	603	68	448	4.8e-14	41.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2904407373	570	94.67	29	457	2	392	1.4e-128	423.4	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2904407377	475	14.64	34	109	145	203	1.4e-14	15	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904407377	475	17.12	104	191	123	191	1.4e-14	17.3	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904407377	475	38.21	187	353	30	183	1.4e-14	18.2	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904407378	266	97.84	46	266	3	228	5.6e-23	76.1	COG1011	FMN phosphatase YigB, HAD superfamily	229
2904407379	135	93.33	1	133	4	129	1.2e-30	100.5	COG3791	Uncharacterized conserved protein	133
2904407380	97	64.89	2	97	40	124	2.2e-16	54	COG3788	Uncharacterized membrane protein YecN, MAPEG domain	131
2904407381	316	98.06	1	312	1	303	7.9e-67	219.8	COG1893	Ketopantoate reductase	307
2904407382	293	79.55	2	135	22	126	1.3e-22	73.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2904407382	293	98.7	140	293	2	153	1.0e-50	165.3	COG3449	DNA gyrase inhibitor GyrI	154
2904407383	454	87.06	69	450	47	389	2.0e-51	170	COG0642	Signal transduction histidine kinase	336
2904407384	245	98.71	11	241	2	230	2.3e-83	273.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904407385	375	66.1	223	268	12	50	1.9e-03	11.1	COG2260	rRNA maturation protein Nop10, contains Zn-ribbon domain	59
2904407385	375	69.31	13	193	57	187	2.8e-22	72.9	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
2904407387	145	98.54	12	131	2	136	8.8e-29	94.5	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2904407388	115	82.96	1	115	4	115	2.4e-32	106.1	COG3791	Uncharacterized conserved protein	133
2904407389	137	89.78	1	133	6	128	3.1e-23	76.6	COG4319	Ketosteroid isomerase homolog	137
2904407390	197	92.09	58	196	6	133	6.3e-28	92	COG5331	Uncharacterized protein	139
2904407391	145	84.17	5	127	7	107	2.9e-29	92.8	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2904407393	111	69.42	5	108	21	104	4.6e-08	27	COG3070	Transcriptional regulator of competence genes, TfoX/Sxy family	121
2904407394	392	72.66	160	390	67	276	9.2e-55	178.7	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
2904407395	210	97.67	8	208	2	211	3.1e-37	122.6	COG0625	Glutathione S-transferase	211
2904407397	114	95.12	1	114	1	117	4.7e-42	137.3	COG3795	Uncharacterized conserved protein	123
2904407398	126	93.5	1	122	1	115	3.0e-41	134.7	COG3795	Uncharacterized conserved protein	123
2904407399	226	96.67	1	226	6	237	2.7e-82	265.3	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
2904407400	144	92.7	1	135	5	131	4.9e-37	121.3	COG4319	Ketosteroid isomerase homolog	137
2904407401	148	93.43	3	140	5	132	3.9e-31	102.2	COG4319	Ketosteroid isomerase homolog	137
2904407402	152	96.82	5	149	4	155	1.4e-29	97.2	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2904407403	138	96.35	2	138	2	133	1.1e-41	136.4	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2904407404	138	97.56	1	125	1	120	2.5e-39	128.4	COG3795	Uncharacterized conserved protein	123
2904407405	175	74.66	27	151	3	111	4.5e-05	10.3	COG3427	Carbon monoxide dehydrogenase subunit G	146
2904407406	133	94.31	1	121	1	116	1.5e-37	122.8	COG3795	Uncharacterized conserved protein	123
2904407407	97	87.88	1	95	3	89	1.4e-07	25.7	COG1359	Quinol monooxygenase YgiN	100
2904407408	211	93.3	4	211	5	185	2.6e-71	233.7	COG3644	Uncharacterized protein	194
2904407409	156	97.81	12	139	2	135	4.3e-38	124.8	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2904407410	447	20.72	10	113	4	89	0.0e+00	101.5	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
2904407410	447	75.9	116	447	97	411	0.0e+00	479.9	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
2904407411	142	80	14	141	2	109	9.8e-28	91	COG3791	Uncharacterized conserved protein	133
2904407412	143	71.6	5	139	39	154	2.5e-11	38.3	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904407414	410	94.03	2	353	9	339	2.6e-96	316.3	COG1566	Multidrug resistance efflux pump	352
2904407415	499	97.83	17	493	3	452	7.7e-91	299.3	COG1538	Outer membrane protein TolC	457
2904407416	531	95.82	8	392	7	373	8.4e-20	66	COG0477	MFS family permease	338
2904407417	297	48.48	124	254	29	60	2.9e-03	11	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
2904407418	523	93.45	1	520	33	546	0.0e+00	549.3	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2904407419	268	58.63	3	247	159	389	5.8e-66	217.8	COG0642	Signal transduction histidine kinase	336
2904407420	90	62.5	1	81	43	117	7.2e-12	40.1	COG1734	RNA polymerase-binding transcription factor DksA	120
2904407423	531	93.44	334	516	9	179	3.8e-54	176.7	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904407425	149	81.25	1	148	13	155	6.9e-20	65.8	COG1714	Uncharacterized membrane protein YckC, RDD family	172
2904407426	606	85.45	1	585	90	741	0.0e+00	452.8	COG0209	Ribonucleotide reductase alpha subunit	696
2904407427	120	78.18	3	119	5	90	6.2e-10	33.2	COG1544	Ribosome-associated translation inhibitor RaiA	110
2904407428	412	98.97	4	407	3	388	6.4e-110	361.6	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
2904407429	323	98.44	1	319	3	318	3.7e-51	168.8	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2904407430	125	93.07	4	101	4	97	1.8e-26	86.2	COG2154	Pterin-4a-carbinolamine dehydratase	101
2904407431	209	99.03	2	206	2	206	1.4e-55	182.4	COG2915	Regulator of phage lambda lysogenization HflD, binds to CII and stimulates its degradation	207
2904407432	118	86.41	1	104	5	93	9.3e-19	61.7	COG1694	NTP pyrophosphatase, house-cleaning of non-canonical NTPs	102
2904407433	102	24.51	4	90	29	90	1.1e-04	16.3	COG1521	Pantothenate kinase type III	251
2904407434	353	88.74	98	353	32	291	1.6e-32	104.9	COG1408	Predicted phosphohydrolase, MPP superfamily	284
2904407436	221	96.17	1	221	10	235	3.1e-57	188.3	COG4089	Uncharacterized membrane protein	235
2904407437	168	93.84	22	168	9	145	1.7e-37	122.6	COG0071	Molecular chaperone IbpA, HSP20 family	146
2904407439	429	97.26	1	428	6	431	0.0e+00	450.5	COG1253	Hemolysin or related protein, contains CBS domains	429
2904407441	203	81	13	196	39	200	9.3e-41	134.3	COG3145	Alkylated DNA repair dioxygenase AlkB	194
2904407442	446	97.07	2	406	12	409	1.9e-122	403	COG1488	Nicotinic acid phosphoribosyltransferase	405
2904407444	68	94.52	1	68	1	69	3.8e-16	53.7	COG2608	Copper chaperone CopZ	71
2904407445	326	98.73	5	326	2	312	4.5e-71	233.8	COG0039	Malate/lactate dehydrogenase	313
2904407446	299	98.71	1	297	4	310	1.3e-117	386.9	COG0078	Ornithine carbamoyltransferase	310
2904407447	395	95.31	1	390	15	400	0.0e+00	487.5	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2904407448	179	87.26	30	179	5	141	6.3e-41	134	COG2193	Bacterioferritin (cytochrome b1)	157
2904407449	628	98.6	1	628	3	634	0.0e+00	755.9	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
2904407450	363	81.86	2	362	49	391	1.7e-116	383.6	COG0498	Threonine synthase	411
2904407451	97	91.92	1	94	2	92	9.2e-07	23.7	COG3668	Plasmid stabilization system protein ParE	98
2904407454	436	28.89	355	418	11	36	1.2e-05	18.6	COG3830	ACT domain, binds amino acids and other small ligands	90
2904407454	436	98.8	1	324	2	331	1.2e-115	380.5	COG0460	Homoserine dehydrogenase	333
2904407455	394	98.23	5	392	4	392	1.7e-126	416.6	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2904407456	259	95.82	3	258	3	254	3.9e-74	243.4	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
2904407457	252	21.32	6	86	139	180	3.4e-25	11.5	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2904407457	252	23.86	124	179	150	196	3.4e-25	33.6	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2904407457	252	35.03	180	251	127	195	3.4e-25	35.3	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2904407458	188	90	3	119	3	101	2.5e-12	41	COG1544	Ribosome-associated translation inhibitor RaiA	110
2904407458	188	97.01	116	181	1	65	3.9e-08	26.9	COG1278	Cold shock protein, CspA family	67
2904407459	164	7.04	17	72	42	66	1.9e-03	6.2	COG1499	NMD protein affecting ribosome stability and mRNA decay	355
2904407459	164	26.76	52	155	128	222	1.9e-03	4.8	COG1499	NMD protein affecting ribosome stability and mRNA decay	355
2904407460	538	88.49	1	248	2	247	2.2e-52	171.8	COG0388	Predicted amidohydrolase	274
2904407460	538	96.72	258	529	4	268	1.7e-77	254.3	COG0171	NH3-dependent NAD+ synthetase	268
2904407463	840	49.14	721	839	2	115	6.9e-46	76.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904407463	840	53.02	83	227	2	124	6.9e-46	74.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904407463	840	63.71	398	703	141	391	4.1e-64	212	COG0642	Signal transduction histidine kinase	336
2904407464	263	95.7	1	257	3	247	3.4e-63	207.7	COG0390	ABC-type iron transport system FetAB, permease component	256
2904407465	236	39.36	3	235	316	535	2.0e-45	149.5	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
2904407466	213	93.85	1	213	12	255	7.9e-53	174	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2904407467	600	95.79	1	468	4	458	0.0e+00	726.3	COG5016	Pyruvate/oxaloacetate carboxyltransferase	472
2904407468	472	71.83	1	470	1	464	0.0e+00	666.4	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2904407470	729	21.64	58	250	73	244	2.8e-32	30.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904407470	729	59.25	209	729	325	795	2.8e-32	80.6	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904407471	563	60.41	10	563	235	591	2.5e-35	116.3	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
2904407472	239	98.28	1	227	3	230	3.7e-84	275.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904407473	547	84.26	6	529	56	387	1.0e-64	210.2	COG0642	Signal transduction histidine kinase	336
2904407475	504	19.53	6	111	85	126	6.7e-14	20.4	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
2904407475	504	28.37	130	223	136	196	6.7e-14	24.2	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
2904407478	72	64.13	1	72	18	76	9.7e-13	41.7	COG5304	Predicted DNA binding protein, CopG/RHH family	92
2904407480	76	64.84	1	75	6	64	1.3e-12	42.3	COG2002	Bifunctional DNA-binding transcriptional regulator of stationary/sporulation/toxin gene expression and antitoxin component of the YhaV-PrlF toxin-antitoxin module	89
2904407483	79	55.43	1	57	41	91	7.9e-17	55.7	COG5304	Predicted DNA binding protein, CopG/RHH family	92
2904407487	339	14.79	247	323	218	259	3.6e-19	22.3	COG5464	Predicted transposase YdaD	289
2904407487	339	41.55	7	134	2	119	3.6e-19	43.5	COG5464	Predicted transposase YdaD	289
2904407490	364	92.53	36	330	13	297	2.2e-54	178.6	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2904407491	692	98.82	1	687	6	674	0.0e+00	765	COG1331	Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains	667
2904407492	404	85.77	2	403	58	473	8.6e-63	206.5	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2904407493	352	74.34	4	352	73	408	8.1e-85	279.3	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
2904407496	392	99.75	1	392	1	393	0.0e+00	508.7	COG0183	Acetyl-CoA acetyltransferase	392
2904407497	248	98.88	1	246	3	267	2.2e-71	234.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904407498	182	79.79	1	167	4	157	3.8e-48	158.4	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
2904407499	454	95.41	1	454	18	474	0.0e+00	491.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2904407500	375	99.73	1	375	1	374	0.0e+00	604.7	COG1883	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit	375
2904407501	597	97.68	1	479	6	469	0.0e+00	752.4	COG5016	Pyruvate/oxaloacetate carboxyltransferase	472
2904407502	82	89.29	3	82	4	78	6.7e-20	65.6	COG3630	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit	84
2904407503	285	85.62	58	204	17	153	8.9e-21	68.4	COG4244	Uncharacterized membrane protein	160
2904407504	348	94.37	114	341	9	226	3.8e-41	135	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
2904407507	343	99.71	11	343	2	339	1.0e-112	370.5	COG0309	Hydrogenase maturation factor	339
2904407508	363	99.46	1	362	1	365	0.0e+00	490.8	COG0409	Hydrogenase maturation factor	364
2904407509	82	86.59	1	81	1	71	1.4e-25	83.4	COG0298	Hydrogenase maturation factor	82
2904407510	768	99.34	12	763	2	748	0.0e+00	789.9	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
2904407511	290	95.45	57	270	8	196	2.4e-66	216.9	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
2904407512	113	98.26	1	113	1	113	5.9e-30	98.1	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
2904407513	350	35.9	193	341	88	227	8.4e-49	71.3	COG5563	Uncharacterized membrane protein	379
2904407513	350	49.49	36	220	117	309	8.4e-49	103.4	COG5563	Uncharacterized membrane protein	379
2904407515	58	90.91	4	58	2	51	9.6e-22	71.2	COG1773	Rubredoxin	55
2904407518	94	56.1	14	71	30	75	5.3e-05	17.2	COG0298	Hydrogenase maturation factor	82
2904407519	200	95.62	1	159	2	154	2.8e-45	148.5	COG0680	Ni,Fe-hydrogenase maturation factor	160
2904407520	228	97.8	1	224	6	227	3.2e-76	250	COG1969	Ni,Fe-hydrogenase I cytochrome b subunit	227
2904407521	195	94.53	1	194	9	198	2.8e-44	145	COG2370	Hydrogenase/urease accessory protein HupE	201
2904407522	597	99.65	16	597	2	564	0.0e+00	802.3	COG0374	Ni,Fe-hydrogenase I large subunit	545
2904407523	366	98.59	4	360	2	351	0.0e+00	504.3	COG1740	Ni,Fe-hydrogenase I small subunit	355
2904407524	375	68.32	2	365	1	276	2.0e-19	63.8	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
2904407525	884	10.12	1	123	2	97	2.3e-21	29.2	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2904407525	884	22.55	199	452	572	785	2.3e-21	15.5	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2904407525	884	36.78	466	851	553	901	2.3e-21	30.3	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2904407529	356	97.31	21	348	2	399	1.6e-39	130.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904407530	455	96.34	2	452	9	456	1.5e-77	255.3	COG2211	Na+/melibiose symporter or related transporter	467
2904407531	404	25	275	391	230	306	1.4e-25	11.4	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2904407531	404	40.58	26	220	22	146	1.4e-25	70.9	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2904407532	464	97.41	33	455	6	418	2.3e-83	273.9	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2904407533	488	96.2	1	483	14	469	0.0e+00	660	COG0362	6-phosphogluconate dehydrogenase	473
2904407534	229	62.33	26	228	80	213	8.7e-15	49.3	COG3577	Predicted aspartyl protease	215
2904407535	774	12	30	85	25	48	8.5e-06	9	COG0218	GTP-binding protein EngB required for normal cell division	200
2904407535	774	48.5	207	325	70	166	8.5e-06	7.5	COG0218	GTP-binding protein EngB required for normal cell division	200
2904407536	292	99.65	1	292	1	288	4.2e-125	411.2	COG3954	Phosphoribulokinase	289
2904407537	259	90.05	1	230	2	200	2.1e-31	103.6	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2904407538	354	100	1	329	1	288	6.5e-107	351.3	COG0191	Fructose/tagatose bisphosphate aldolase	286
2904407539	696	99.4	25	696	3	661	0.0e+00	1035.1	COG0021	Transketolase	663
2904407540	328	99.01	6	321	2	302	1.8e-104	343.9	COG0176	Transaldolase	239
2904407542	177	86.63	2	176	28	202	2.3e-41	134.1	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
2904407543	213	96.77	1	212	1	210	3.1e-64	210.6	COG0269	3-keto-L-gulonate-6-phosphate decarboxylase	217
2904407544	191	27.65	20	161	60	153	7.7e-04	12.6	COG2130	NADPH-dependent curcumin reductase CurA	340
2904407545	265	97.57	13	265	3	243	3.9e-95	311.9	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
2904407546	62	92.42	1	59	1	61	8.2e-26	84	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
2904407547	209	60.12	1	207	122	323	1.0e-56	186.8	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
2904407548	140	97.12	1	136	2	136	5.6e-33	108.1	COG0848	Biopolymer transport protein ExbD	137
2904407549	205	90.74	1	205	12	207	9.2e-46	150.9	COG0811	Biopolymer transport protein ExbB/TolQ	216
2904407550	688	88.32	336	470	5	125	6.9e-14	45.7	COG3011	Predicted thiol-disulfide oxidoreductase YuxK, DCC family	137
2904407551	93	96.77	1	91	3	92	1.4e-28	93.6	COG1254	Acylphosphatase	92
2904407552	715	83.21	374	715	60	386	6.5e-113	370.4	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
2904407552	715	94.75	1	368	17	377	2.1e-123	404.5	COG0116	23S rRNA G2445 N2-methylase RlmL	381
2904407553	186	91.37	1	178	17	196	1.3e-68	225.1	COG4764	Uncharacterized protein	197
2904407554	603	95.22	2	600	23	600	1.1e-124	411.2	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
2904407557	302	91.8	1	302	8	287	8.0e-45	146	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2904407558	389	15.21	272	335	79	111	9.6e-65	5	COG0269	3-keto-L-gulonate-6-phosphate decarboxylase	217
2904407558	389	98.62	1	215	1	214	9.6e-65	207.2	COG0269	3-keto-L-gulonate-6-phosphate decarboxylase	217
2904407559	461	96.79	11	461	3	455	0.0e+00	588	COG0055	FoF1-type ATP synthase, beta subunit	468
2904407561	153	67.11	1	152	51	201	8.5e-58	189.6	COG4149	ABC-type molybdate transport system, permease component	225
2904407562	137	66.67	2	63	23	68	9.8e-21	6.8	COG3585	Molybdopterin-binding protein	69
2904407562	137	94.2	66	133	3	67	9.8e-21	60.7	COG3585	Molybdopterin-binding protein	69
2904407563	284	95.37	21	280	9	255	6.9e-25	81	COG0730	Uncharacterized membrane protein YfcA	258
2904407564	268	97.75	6	261	3	263	1.7e-54	179.1	COG0725	ABC-type molybdate transport system, periplasmic component	258
2904407565	509	31.03	3	161	134	268	6.8e-42	41.1	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2904407565	509	35.63	283	470	278	432	6.8e-42	95.3	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2904407566	432	99.49	28	431	3	396	0.0e+00	521.3	COG0372	Citrate synthase	390
2904407567	697	96.86	4	697	26	795	3.6e-60	193.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904407568	156	93.1	11	155	8	142	4.0e-36	118.3	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2904407570	412	75.35	29	394	89	470	2.0e-66	217.3	COG4287	PhoPQ-activated pathogenicity-related protein	507
2904407573	110	26.75	1	110	120	207	1.7e-20	68.2	COG0724	 RNA recognition motif (RRM) domain	306
2904407574	193	96.84	1	193	5	188	1.3e-28	94.2	COG3009	Uncharacterized lipoprotein YmbA	190
2904407575	551	94.58	9	551	20	542	0.0e+00	491.8	COG3008	Paraquat-inducible protein B	553
2904407576	399	90.91	3	399	33	412	4.0e-115	377.3	COG2995	Uncharacterized paraquat-inducible protein A	418
2904407577	97	99	1	97	1	99	2.9e-30	98.8	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
2904407579	649	96.89	1	583	5	564	0.0e+00	629.2	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2904407580	444	17.07	125	190	12	60	4.3e-73	17	COG4976	Predicted methyltransferase, contains TPR repeat	287
2904407580	444	18.82	59	130	12	65	4.3e-73	22.4	COG4976	Predicted methyltransferase, contains TPR repeat	287
2904407580	444	84.67	185	444	43	285	4.3e-73	201.3	COG4976	Predicted methyltransferase, contains TPR repeat	287
2904407586	903	99.13	12	903	2	799	0.0e+00	961.2	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2904407587	343	97.01	1	337	6	330	5.8e-104	342.2	COG3520	Predicted component of the type VI protein secretion system	335
2904407588	625	99.84	1	625	1	620	0.0e+00	723.4	COG3519	Type VI protein secretion system component VasA	621
2904407589	166	97.45	4	164	2	154	4.6e-38	124.4	COG3518	Predicted component of the type VI protein secretion system	157
2904407590	272	96.7	1	271	5	268	6.2e-94	308.8	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion	273
2904407591	160	98.1	1	160	1	155	8.1e-46	150.1	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2904407592	498	99.19	1	497	4	494	0.0e+00	766.7	COG3517	Predicted component of the type VI protein secretion system	495
2904407593	176	97.63	2	169	2	166	9.6e-71	231.1	COG3516	Predicted component of the type VI protein secretion system	169
2904407594	350	94.05	9	341	11	342	4.6e-41	135.1	COG3515	Predicted component of the type VI protein secretion system	346
2904407595	467	44.77	274	467	81	187	1.9e-14	47.5	COG5571	Uncharacterized protein YhjY, contains autotransporter beta-barrel domain	239
2904407596	510	91.18	270	510	11	258	2.1e-48	159	COG0631	Serine/threonine protein phosphatase PrpC	262
2904407596	510	93.83	2	239	6	218	1.9e-46	149.2	COG3913	Uncharacterized protein	227
2904407597	1186	99.33	2	1186	8	1190	0.0e+00	1048.8	COG3523	Type VI protein secretion system component VasK	1188
2904407598	440	52.76	267	440	92	196	1.2e-17	58.6	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2904407598	440	94.32	19	283	14	262	2.9e-79	260.4	COG3455	Type VI protein secretion system component VasF	262
2904407600	445	99.78	1	444	1	445	0.0e+00	536.6	COG3522	Predicted component of the type VI protein secretion system	446
2904407601	524	99.07	1	521	2	429	9.4e-70	225.9	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
2904407602	166	88.82	1	159	7	149	5.1e-36	118	COG3521	Predicted component of the type VI protein secretion system	159
2904407603	281	13.56	218	268	240	279	3.8e-10	7.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904407603	281	22.37	15	211	63	128	3.8e-10	26.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904407604	963	7.59	408	476	224	288	1.4e-71	30.3	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904407604	963	8.29	71	146	58	128	1.4e-71	19.1	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904407604	963	8.76	122	204	44	118	1.4e-71	15.5	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904407604	963	12.03	471	586	36	138	1.4e-71	57.6	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904407604	963	12.15	207	319	8	111	1.4e-71	48.4	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904407604	963	13.08	309	422	19	130	1.4e-71	42.6	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904407604	963	38.79	530	944	419	750	1.4e-71	89.2	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904407606	143	13.9	4	133	571	689	1.3e-14	47.8	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904407611	167	32.78	39	159	127	205	7.6e-10	33.3	COG4083	Exosortase/Archaeosortase	239
2904407613	390	92.98	1	384	24	407	3.7e-73	240.9	COG1373	Predicted ATPase, AAA+ superfamily	398
2904407614	481	47.67	225	465	43	175	1.5e-06	22	COG0500	SAM-dependent methyltransferase	257
2904407615	850	83.54	243	406	26	157	2.3e-11	38.2	COG0639	Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family	155
2904407615	850	99.41	7	175	2	169	1.9e-45	148.4	COG4639	Predicted kinase	168
2904407616	68	45	1	53	8	43	6.3e-06	20.6	COG4710	Predicted DNA-binding protein with an HTH domain	80
2904407618	112	23.75	14	94	226	296	1.4e-04	15.5	COG1230	Co/Zn/Cd efflux system component	296
2904407620	260	94.49	4	258	10	266	1.7e-31	103.9	COG0428	Zinc transporter ZupT	266
2904407622	558	96.17	1	543	9	561	0.0e+00	454.7	COG1229	Formylmethanofuran dehydrogenase subunit A	575
2904407623	328	96.32	9	316	1	314	3.9e-66	217.8	COG0523	GTPase, G3E family	323
2904407624	144	76.97	20	143	4	120	5.4e-31	101.8	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
2904407625	274	95.86	1	265	6	283	6.7e-79	259.3	COG1469	GTP cyclohydrolase FolE2	289
2904407626	449	99.39	9	449	1	324	2.9e-111	362.5	COG0523	GTPase, G3E family	323
2904407627	343	33.13	5	136	299	463	2.6e-38	59.4	COG2319	WD40 repeat	466
2904407627	343	50.8	101	335	159	411	2.6e-38	73.3	COG2319	WD40 repeat	466
2904407629	311	95.17	173	310	2	139	1.8e-41	135.7	COG4275	Uncharacterized protein	143
2904407630	518	65.48	257	451	9	137	2.2e-67	39.6	COG2059	Chromate transport protein ChrA	195
2904407630	518	87.82	19	210	7	179	2.2e-67	191.2	COG2059	Chromate transport protein ChrA	195
2904407631	525	96.32	1	524	11	534	2.9e-83	274.4	COG1178	ABC-type Fe3+ transport system, permease component	540
2904407632	279	63.17	26	259	3	225	6.5e-86	282.8	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2904407633	145	95.17	1	144	5	142	1.2e-55	182.2	COG4275	Uncharacterized protein	143
2904407637	333	97.67	42	333	1	294	6.7e-49	161.1	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2904407638	364	76.81	16	361	75	339	6.8e-70	229.7	COG4861	Uncharacterized protein	345
2904407639	287	94.8	6	287	11	265	7.0e-62	203.3	COG4849	Predicted nucleotidyltransferase	269
2904407640	63	47.2	6	63	2	60	9.3e-13	43.1	COG3293	Transposase	124
2904407641	408	43.59	221	343	17	84	1.8e-04	15	COG0328	Ribonuclease HI	154
2904407642	122	91.73	1	122	6	127	5.2e-33	108.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2904407643	111	79.49	1	106	9	101	2.2e-16	54	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2904407644	720	17.24	1	159	7	136	0.0e+00	91.4	COG0643	Chemotaxis protein histidine kinase CheA	716
2904407644	720	67.24	152	719	240	746	0.0e+00	535.1	COG0643	Chemotaxis protein histidine kinase CheA	716
2904407645	543	91.53	70	504	37	425	1.2e-87	288.4	COG0840	Methyl-accepting chemotaxis protein	408
2904407646	180	92.73	5	172	9	161	9.2e-46	149.6	COG0835	Chemotaxis signal transduction protein	165
2904407647	268	98.52	8	268	2	267	1.3e-74	245.1	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2904407648	178	90.85	9	168	8	156	6.9e-31	101.1	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
2904407649	357	97.73	3	357	2	345	1.7e-125	413	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2904407650	987	64.25	496	972	219	644	1.1e-118	391.1	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2904407651	491	62.93	106	486	139	374	2.8e-69	228.5	COG4585	Signal transduction histidine kinase	365
2904407652	207	99.05	2	207	1	209	4.0e-64	210.4	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2904407653	316	81.31	9	312	6	253	5.6e-40	131.4	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2904407659	190	60.77	72	178	3	81	1.2e-05	20.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2904407662	138	96.97	1	137	3	130	2.4e-33	109.5	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
2904407663	82	47.62	1	80	4	43	3.8e-04	14.9	COG4118	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor	84
2904407664	928	64.27	100	581	65	377	4.8e-21	67.9	COG1061	Superfamily II DNA or RNA helicase	442
2904407665	1768	5.43	669	1090	326	372	6.1e-28	18.7	COG1201	Lhr-like helicase	814
2904407665	1768	21.73	85	295	23	210	6.1e-28	71	COG1201	Lhr-like helicase	814
2904407666	137	93.28	1	131	3	127	5.2e-15	50.2	COG4113	Predicted nucleic acid-binding protein, contains PIN domain	134
2904407667	79	37.5	1	59	3	32	1.5e-03	12.8	COG4691	Plasmid stability protein	80
2904407669	405	46.21	222	404	19	195	3.2e-27	32.9	COG0477	MFS family permease	338
2904407669	405	65.01	9	267	4	252	3.2e-27	55.5	COG0477	MFS family permease	338
2904407670	669	94.47	3	669	45	795	6.4e-77	249.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904407671	847	16.87	297	405	81	148	1.1e-34	35.4	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904407671	847	19.11	47	144	120	196	1.1e-34	14.7	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904407671	847	41.44	117	299	87	253	1.1e-34	70.9	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904407672	984	31.76	277	449	20	147	1.1e-37	57.8	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904407672	984	43.92	34	344	130	306	1.1e-37	37.1	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904407672	984	90.57	351	948	38	402	1.1e-37	59.7	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904407673	68	29.91	6	68	63	97	3.7e-05	18.5	COG2963	Transposase and inactivated derivatives	116
2904407676	237	57.31	30	218	137	328	1.3e-22	74.9	COG0582	Integrase	309
2904407678	538	95.59	472	534	2	66	7.4e-14	44.8	COG1141	Ferredoxin	68
2904407678	538	98.1	6	449	7	419	1.7e-82	271.6	COG2124	Cytochrome P450	411
2904407680	675	14.7	113	243	1	76	5.4e-62	44.9	COG1657	Squalene cyclase	517
2904407680	675	61.32	320	673	197	513	5.4e-62	163.7	COG1657	Squalene cyclase	517
2904407681	450	95.17	9	390	2	375	2.2e-48	159.7	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2904407682	297	93.61	1	297	2	250	8.2e-60	196.9	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
2904407683	721	96.9	22	696	20	645	0.0e+00	473.3	COG3408	Glycogen debranching enzyme (alpha-1,6-glucosidase)	641
2904407684	373	97.8	1	341	6	405	5.3e-40	128.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904407685	332	91.97	51	332	24	298	1.8e-49	162.6	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
2904407686	626	88.92	12	417	7	295	4.4e-38	125.2	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2904407689	90	94.68	1	90	2	90	5.0e-36	117.2	COG0776	Bacterial nucleoid DNA-binding protein	94
2904407690	808	99.11	7	786	4	780	0.0e+00	1141.8	COG0466	ATP-dependent Lon protease, bacterial type	782
2904407691	426	98.78	18	425	1	404	0.0e+00	686.6	COG1219	ATP-dependent protease Clp, ATPase subunit	408
2904407692	214	96	14	213	3	194	2.2e-89	292.7	COG0740	ATP-dependent protease ClpP, protease subunit	200
2904407693	440	98.88	1	435	1	443	5.3e-127	418.5	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
2904407696	1281	13.35	5	187	309	449	0.0e+00	33.8	COG3459	Cellobiose phosphorylase	1056
2904407696	1281	99.62	202	1281	1	1052	0.0e+00	933.2	COG3459	Cellobiose phosphorylase	1056
2904407698	263	74.25	34	257	44	242	3.6e-46	151.8	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2904407700	234	53.41	6	228	29	177	1.5e-07	26.3	COG0500	SAM-dependent methyltransferase	257
2904407701	129	78.52	2	126	24	140	3.2e-45	147.7	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
2904407702	1168	99.91	1	1166	1	1167	0.0e+00	909.6	COG1196	Chromosome segregation ATPase	1163
2904407703	245	27.47	4	109	4	92	1.0e-34	17.7	COG3115	Cell division protein ZipA, interacts with FtsZ	324
2904407703	245	41.05	91	245	186	318	1.0e-34	96.7	COG3115	Cell division protein ZipA, interacts with FtsZ	324
2904407704	670	99.26	2	669	5	673	0.0e+00	940.2	COG0272	NAD-dependent DNA ligase	667
2904407706	79	23.77	2	72	196	258	2.9e-08	27.5	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
2904407707	160	99.32	1	145	1	145	1.2e-48	158.7	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
2904407708	153	46.69	5	135	130	242	6.4e-18	59.5	COG2202	PAS domain	232
2904407709	156	52.23	4	154	7	88	2.2e-04	14	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2904407710	384	93.41	10	378	5	387	4.6e-41	134.4	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2904407711	123	87.22	4	123	4	119	2.4e-34	112.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2904407714	160	43.33	6	143	27	91	3.5e-07	24.8	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2904407715	272	70.71	43	247	51	219	5.1e-24	78.7	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2904407716	136	90	1	121	4	111	8.7e-09	30.2	COG2105	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family	120
2904407717	111	79.49	1	111	15	107	1.9e-25	83.3	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2904407718	143	68.49	11	143	37	136	2.1e-19	63.8	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2904407719	1119	68.86	1	1114	484	1580	0.0e+00	1003.9	COG2902	NAD-specific glutamate dehydrogenase	1592
2904407722	112	17.82	1	111	82	184	1.0e+00	1.9	COG3356	Predicted membrane-associated lipid hydrolase, neutral ceramidase superfamily	578
2904407723	439	97.95	1	434	5	433	0.0e+00	437.4	COG1253	Hemolysin or related protein, contains CBS domains	429
2904407724	553	71.59	19	543	45	490	1.4e-110	365.1	COG3211	Secreted phosphatase, PhoX family	616
2904407725	523	65.22	1	226	114	353	1.1e-36	43.6	COG0457	Tetratricopeptide (TPR) repeat	291
2904407725	523	65.76	299	518	103	344	1.1e-36	52.5	COG0457	Tetratricopeptide (TPR) repeat	291
2904407725	523	75.54	164	433	61	338	1.1e-36	53.4	COG0457	Tetratricopeptide (TPR) repeat	291
2904407730	942	64.1	426	933	214	638	3.0e-99	326.8	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2904407732	148	32	20	148	132	235	6.3e-04	13.1	COG0226	ABC-type phosphate transport system, periplasmic component	318
2904407734	704	90.12	51	578	29	484	1.4e-116	383.8	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
2904407735	314	96.76	1	309	8	306	4.7e-73	240.2	COG0650	Formate hydrogenlyase subunit 4	309
2904407736	226	97.71	7	222	5	217	1.9e-32	107	COG4237	Hydrogenase-4 membrane subunit HyfE	218
2904407737	488	93.87	1	486	7	481	4.2e-91	300.2	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
2904407738	546	89.52	3	536	20	523	3.4e-90	296.9	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2904407739	547	95.26	183	547	5	366	1.9e-99	327.1	COG3261	Ni,Fe-hydrogenase III large subunit	382
2904407740	178	89.86	38	177	2	134	1.4e-52	171.1	COG3260	Ni,Fe-hydrogenase III small subunit	148
2904407741	126	88.97	1	126	1	129	1.1e-33	110.5	COG3304	Uncharacterized membrane protein YccF, DUF307 family	145
2904407742	517	85.03	5	508	56	390	6.1e-70	229.6	COG0642	Signal transduction histidine kinase	336
2904407743	366	70.31	131	366	84	289	1.4e-27	90.7	COG0842	ABC-type multidrug transport system, permease component	286
2904407744	314	98.37	4	307	4	304	1.7e-87	287.9	COG1131	ABC-type multidrug transport system, ATPase component	293
2904407745	326	66.76	30	288	52	286	1.1e-31	103.8	COG1566	Multidrug resistance efflux pump	352
2904407746	884	99.42	1	878	5	866	0.0e+00	857.1	COG0308	Aminopeptidase N	859
2904407748	443	39.08	2	219	16	210	2.6e-87	178.2	COG3104	Dipeptide/tripeptide permease	498
2904407748	443	41.08	212	442	285	489	2.6e-87	115.7	COG3104	Dipeptide/tripeptide permease	498
2904407749	317	95.63	89	312	6	180	1.0e-37	123.7	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904407750	189	96.77	1	182	6	185	7.4e-51	166.4	COG1628	Endonuclease V homolog, UPF0215 family	185
2904407751	102	90	6	97	2	73	2.0e-05	17.7	COG5645	Uncharacterized conserved protein YceK	80
2904407752	342	98.24	1	342	4	338	4.1e-86	283.3	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2904407756	1036	99.42	1	1028	1	1024	0.0e+00	862.8	COG3696	Cu/Ag efflux pump CusA	1027
2904407757	184	91.53	35	184	12	184	3.5e-32	105.9	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2904407758	247	95.05	63	246	9	200	1.0e-63	208.5	COG1573	Uracil-DNA glycosylase	202
2904407759	515	99.76	3	415	2	413	0.0e+00	522.2	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2904407760	247	95.78	8	245	4	230	1.4e-71	235.1	COG1183	Phosphatidylserine synthase	234
2904407761	338	99.11	1	336	3	337	0.0e+00	541.3	COG0059	Ketol-acid reductoisomerase	338
2904407762	163	97.53	1	161	3	160	2.1e-65	213.8	COG0440	Acetolactate synthase, small subunit	163
2904407763	576	99.64	2	566	2	554	0.0e+00	756.2	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2904407765	272	96.38	3	267	4	269	4.9e-88	289.2	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
2904407766	218	96.97	4	217	2	225	8.1e-27	88.8	COG1011	FMN phosphatase YigB, HAD superfamily	229
2904407767	108	34.43	1	108	25	129	5.0e-32	106.1	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2904407768	418	98.58	1	418	5	420	0.0e+00	718.7	COG1158	Transcription termination factor Rho	422
2904407769	497	93.32	42	488	16	434	3.3e-118	389.4	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
2904407770	637	88.46	2	203	12	195	3.9e-45	148.3	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2904407771	426	97.45	1	426	8	428	0.0e+00	628.4	COG0001	Glutamate-1-semialdehyde aminotransferase	432
2904407772	177	91.35	1	177	14	182	1.5e-61	201.7	COG0717	Deoxycytidine triphosphate deaminase	183
2904407773	362	95.8	36	313	12	285	8.9e-97	317.7	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2904407774	695	76.76	575	694	7	115	2.4e-34	111.7	COG0073	tRNA-binding EMAP/Myf domain	123
2904407774	695	99.46	1	559	3	558	0.0e+00	660.1	COG0143	Methionyl-tRNA synthetase	558
2904407777	201	88.04	1	193	5	188	5.6e-25	83.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904407778	162	95.21	5	162	4	142	3.2e-14	47.1	COG3418	Flagellar biosynthesis/type III secretory pathway chaperone	146
2904407779	100	81.72	1	96	17	92	1.9e-08	29.3	COG2747	Negative regulator of flagellin synthesis (anti-sigma28 factor)	93
2904407780	232	94.09	5	232	12	218	4.2e-40	132.1	COG1261	Flagella basal body P-ring formation protein FlgA	220
2904407781	317	62.38	173	316	4	129	1.7e-08	27.9	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2904407781	317	93.33	3	164	5	158	3.6e-45	147.1	COG0835	Chemotaxis signal transduction protein	165
2904407782	280	98.15	7	279	3	267	7.2e-82	268.9	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2904407783	130	98.52	2	130	2	134	2.0e-38	126.1	COG1815	Flagellar basal body rod protein FlgB	133
2904407784	139	100	1	138	1	138	1.9e-49	161.6	COG1558	Flagellar basal body rod protein FlgC	137
2904407785	222	90.13	1	221	15	215	7.4e-45	147.5	COG1843	Flagellar hook assembly protein FlgD	222
2904407786	421	99.36	1	421	3	471	3.0e-110	363.9	COG1749	Flagellar hook protein FlgE	423
2904407787	246	99.6	1	246	1	250	3.7e-100	329	COG4787	Flagellar basal body rod protein FlgF	251
2904407788	262	98.11	1	262	4	263	6.7e-101	331.5	COG4786	Flagellar basal body rod protein FlgG	265
2904407789	225	98.7	1	222	3	230	2.2e-65	214.7	COG2063	Flagellar basal body L-ring protein FlgH	230
2904407790	369	98.63	5	369	6	365	0.0e+00	474.2	COG1706	Flagellar basal body P-ring protein FlgI	365
2904407791	324	67.5	15	321	73	261	2.9e-61	201.5	COG1705	Flagellum-specific peptidoglycan hydrolase FlgJ	201
2904407792	557	99.32	1	556	4	587	0.0e+00	449.9	COG1256	Flagellar hook-associated protein FlgK	552
2904407793	432	99.23	1	432	1	385	6.1e-65	214.3	COG1344	Flagellin and related hook-associated protein FlgL	360
2904407794	828	99.28	3	828	6	828	0.0e+00	786.7	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
2904407798	329	83.28	2	327	48	331	7.0e-99	325.8	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2904407799	645	100	67	627	1	552	0.0e+00	809.9	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2904407800	112	100	1	112	1	112	1.6e-50	164.6	COG0347	Nitrogen regulatory protein PII	112
2904407801	191	96.99	8	139	4	132	4.0e-20	66.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
2904407806	429	96.26	1	429	12	474	3.2e-90	297.6	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2904407807	473	98.94	1	473	4	470	0.0e+00	648.7	COG2870	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase	467
2904407808	461	99.31	16	452	1	433	0.0e+00	565.7	COG0305	Replicative DNA helicase	435
2904407809	360	98.63	1	357	2	360	4.5e-121	398.3	COG0787	Alanine racemase	360
2904407811	132	95	5	129	2	115	7.8e-24	78.7	COG1734	RNA polymerase-binding transcription factor DksA	120
2904407812	295	88.82	1	295	36	321	1.3e-98	324.4	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
2904407813	188	99.24	1	131	2	131	2.3e-47	153.8	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
2904407814	326	87.57	1	326	14	337	4.5e-114	375.2	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
2904407815	691	99.14	1	691	5	692	0.0e+00	1057.5	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
2904407816	89	96.63	1	89	4	89	1.4e-35	115.6	COG0184	Ribosomal protein S15P/S13E	89
2904407817	309	97.1	2	300	8	308	1.6e-101	334	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
2904407818	85	68.07	1	82	37	117	1.1e-25	84.2	COG0858	Ribosome-binding factor A	118
2904407819	882	46.62	68	403	32	224	4.5e-05	16	COG1419	Flagellar biosynthesis GTPase FlhF	407
2904407819	882	98.93	382	882	3	557	0.0e+00	558.9	COG0532	Translation initiation factor IF-2, a GTPase	509
2904407820	501	97.99	165	379	1	195	1.9e-79	260.2	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
2904407821	150	96.1	1	148	7	154	3.8e-51	167.2	COG0779	Ribosome maturation factor RimP	153
2904407822	124	89.47	13	121	10	111	1.3e-22	74.1	COG0607	Rhodanese-related sulfurtransferase	110
2904407823	124	88	1	94	9	96	9.0e-32	103.5	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
2904407824	452	98.65	8	452	4	442	0.0e+00	526.5	COG1570	Exonuclease VII, large subunit	440
2904407825	724	92.22	475	721	6	242	6.5e-74	240.6	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2904407825	724	92.35	279	461	13	181	2.3e-53	174.1	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904407826	258	62.82	1	249	11	255	1.7e-56	185.8	COG0426	Flavorubredoxin	388
2904407827	136	86.76	1	129	8	125	1.2e-09	31.5	COG3631	Ketosteroid isomerase-related protein	133
2904407828	201	59.88	16	187	25	121	4.0e-04	15.4	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904407829	290	95.68	4	288	3	268	2.2e-45	149	COG0388	Predicted amidohydrolase	274
2904407831	821	98.94	10	819	7	750	0.0e+00	946.9	COG0058	Glucan phosphorylase	750
2904407832	634	76.67	27	223	49	209	1.5e-24	80.2	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
2904407832	634	90.41	249	620	28	357	3.8e-73	240.4	COG1858	Cytochrome c peroxidase	364
2904407833	162	90.68	13	162	8	153	2.9e-40	131.9	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
2904407838	96	94.95	1	96	4	97	8.0e-24	78.5	COG3668	Plasmid stabilization system protein ParE	98
2904407839	88	91.57	2	84	3	78	3.9e-24	78.7	COG3905	Predicted transcriptional regulator	83
2904407840	318	64.62	1	315	4	87	1.1e-14	48.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2904407843	86	35.29	1	83	7	54	1.2e-04	16.5	COG0864	Metal-responsive transcriptional regulator, contains CopG/Arc/MetJ DNA-binding domain	136
2904407844	135	97.16	6	131	2	138	5.0e-13	43.1	COG1848	Predicted nucleic acid-binding protein, contains PIN domain	140
2904407846	501	96.31	30	467	4	473	5.9e-74	244.2	COG3119	Arylsulfatase A or related enzyme	475
2904407847	564	87.91	90	520	4	432	3.1e-82	271.5	COG3119	Arylsulfatase A or related enzyme	475
2904407848	815	99.39	69	613	2	486	0.0e+00	479	COG3119	Arylsulfatase A or related enzyme	475
2904407849	276	92.14	2	275	17	274	5.1e-108	354.4	COG2998	ABC-type tungstate transport system, permease component	280
2904407850	83	93.9	1	83	3	79	4.6e-22	72.3	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
2904407852	475	96.75	11	474	3	478	2.5e-93	307.5	COG0531	Amino acid transporter	466
2904407853	149	64.52	1	143	71	210	3.2e-29	96.2	COG5637	Uncharacterized membrane protein	217
2904407854	124	47.62	3	109	77	166	2.4e-13	44.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2904407857	369	96.25	7	358	2	360	1.7e-61	202.4	COG4641	Spore maturation protein CgeB	373
2904407858	394	95.44	7	364	2	357	3.2e-72	237.7	COG4641	Spore maturation protein CgeB	373
2904407859	378	96.51	3	374	4	363	6.1e-65	213.8	COG4641	Spore maturation protein CgeB	373
2904407860	380	97.07	2	354	11	407	1.4e-29	97.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904407861	342	86.89	16	341	4	308	2.0e-62	205.7	COG0673	Predicted dehydrogenase	342
2904407862	335	24.36	20	110	3	88	2.6e-55	60.2	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2904407862	335	63.17	107	335	128	350	2.6e-55	120.9	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2904407863	386	98.44	19	358	4	319	9.2e-79	259.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2904407864	371	98.75	1	353	2	318	7.9e-89	292.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2904407865	330	98.13	3	317	3	317	3.0e-70	231.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2904407866	290	99.25	41	288	2	267	1.8e-69	228.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904407867	140	99.39	3	121	1	162	1.3e-26	87.9	COG0517	CBS domain	117
2904407868	340	95.71	14	311	11	300	1.4e-71	235.2	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2904407869	405	58.65	135	230	34	94	5.8e-04	10.9	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2904407870	101	59.55	1	101	66	171	1.7e-05	18.8	COG1633	Rubrerythrin	176
2904407872	105	12.94	5	96	109	167	7.1e-07	22.2	COG2233	Xanthine/uracil permease	451
2904407874	343	95.85	4	266	6	259	7.8e-58	189.8	COG0300	Short-chain dehydrogenase	265
2904407875	146	74.72	8	145	35	167	1.2e-03	10.2	COG1633	Rubrerythrin	176
2904407876	172	26.47	13	166	79	123	1.2e-01	4	COG4803	Uncharacterized membrane protein	170
2904407877	63	91.04	1	63	4	64	5.1e-24	78.6	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2904407878	52	22.62	1	52	66	84	7.2e-10	32.4	COG5508	Uncharacterized protein	84
2904407879	122	93.23	2	122	2	125	1.0e-25	84.9	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
2904407880	126	97.44	7	123	3	116	4.5e-28	91.7	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
2904407881	595	99.65	5	579	2	565	0.0e+00	772.3	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2904407882	260	97.87	26	260	3	232	8.8e-91	297.4	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
2904407883	94	86.17	4	94	10	90	2.5e-22	72.9	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
2904407885	230	91.15	7	222	14	219	2.7e-77	253.2	COG4340	Uncharacterized protein	226
2904407886	579	96.03	8	572	10	468	9.1e-60	196.2	COG1109	Phosphomannomutase	464
2904407887	417	98.78	2	416	3	406	0.0e+00	436.4	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
2904407889	862	63.2	420	840	141	389	8.4e-64	211	COG0642	Signal transduction histidine kinase	336
2904407890	407	97.19	1	406	4	384	4.6e-128	421.6	COG0448	ADP-glucose pyrophosphorylase	393
2904407891	198	35.6	32	175	8	117	3.9e-04	13.5	COG4965	Flp pilus assembly protein TadB	309
2904407893	610	91.44	132	563	25	387	1.2e-63	207.9	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2904407894	666	30.36	566	665	154	221	8.9e-26	41.9	COG0569	Trk K+ transport system, NAD-binding component	225
2904407894	666	54.46	413	544	3	124	8.9e-26	42.2	COG0569	Trk K+ transport system, NAD-binding component	225
2904407894	666	96.57	1	393	3	396	5.3e-121	398.3	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
2904407896	122	93.33	12	122	6	103	6.7e-30	97.5	COG0023	Translation initiation factor 1 (eIF-1/SUI1)	104
2904407897	100	21.09	3	90	186	243	2.3e-04	15.4	COG1967	Uncharacterized membrane protein	271
2904407898	1258	50.83	703	828	120	242	5.5e-63	45.8	COG2202	PAS domain	232
2904407898	1258	57.85	552	704	103	242	5.5e-63	46.7	COG2202	PAS domain	232
2904407898	1258	67.01	926	1246	125	388	8.9e-68	224	COG0642	Signal transduction histidine kinase	336
2904407898	1258	71.07	48	267	71	242	5.5e-63	45.5	COG2202	PAS domain	232
2904407898	1258	97.93	315	561	6	242	5.5e-63	78.4	COG2202	PAS domain	232
2904407899	191	94.62	7	189	3	178	3.2e-50	164.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2904407900	522	32.65	410	522	87	134	1.1e-03	13	COG1388	LysM repeat	124
2904407903	233	93.72	3	231	15	238	1.0e-27	91	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2904407904	541	43.6	287	533	3	169	7.5e-32	12.9	COG0477	MFS family permease	338
2904407904	541	75.98	34	332	4	294	7.5e-32	97.6	COG0477	MFS family permease	338
2904407905	134	97.55	3	126	1	159	1.6e-15	51.1	COG0517	CBS domain	117
2904407906	116	92.86	3	111	2	105	5.8e-04	14.6	COG0347	Nitrogen regulatory protein PII	112
2904407909	410	96.5	4	407	6	391	1.4e-87	288.1	COG0475	Kef-type K+ transport system, membrane component KefB	397
2904407910	407	78.53	252	384	36	163	1.6e-11	38.6	COG0517	CBS domain	117
2904407910	407	97.46	4	262	4	233	9.8e-30	98	COG1994	Zn-dependent protease (includes SpoIVFB)	230
2904407911	241	90.54	8	235	4	204	2.0e-52	172	COG2928	Uncharacterized membrane protein	222
2904407912	582	15.08	494	582	408	480	5.4e-81	66.6	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904407912	582	85.74	9	468	2	416	5.4e-81	206.8	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904407913	80	79.76	1	77	2	68	3.8e-08	27.6	COG4568	Transcriptional antiterminator Rof (Rho-off)	84
2904407914	170	75	53	165	26	112	7.3e-12	38.9	COG3450	Predicted enzyme of the cupin superfamily	116
2904407915	172	94.86	1	172	8	173	5.2e-59	192.9	COG3040	Bacterial lipocalin	174
2904407917	370	95.81	1	369	16	381	7.2e-105	345	COG1423	ATP-dependent RNA circularization protein, DNA/RNA ligase (PAB1020)  family	382
2904407918	203	95.48	1	201	3	213	1.3e-62	205.4	COG1458	Predicted DNA-binding protein containing PIN domain, UPF0278 family	221
2904407920	570	50.22	118	260	26	137	1.6e-30	49.4	COG1226	Voltage-gated potassium channel Kch	212
2904407920	570	84.75	276	474	21	209	1.6e-30	51.7	COG1226	Voltage-gated potassium channel Kch	212
2904407921	470	96.41	9	468	14	416	9.1e-36	117.9	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2904407925	256	44.5	61	228	120	216	3.9e-07	23.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2904407926	291	70.33	22	284	13	223	1.2e-16	54.8	COG0731	Wyosine [tRNA(Phe)-imidazoG37] synthetase, radical SAM superfamily	296
2904407929	242	51.79	3	238	29	230	5.5e-21	68.9	COG0426	Flavorubredoxin	388
2904407931	199	85.32	2	190	29	214	2.8e-35	115.8	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2904407934	361	96.41	90	259	1	161	2.6e-53	173.6	COG4335	3-methyladenine DNA glycosylase AlkC	167
2904407937	493	21.21	58	182	62	145	3.2e-13	28.5	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
2904407937	493	43.69	190	467	57	229	3.2e-13	13	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
2904407939	206	96.39	15	203	5	191	3.4e-26	86.7	COG0558	Phosphatidylglycerophosphate synthase	192
2904407940	313	99.34	8	313	3	303	4.8e-128	421.4	COG4589	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase	303
2904407941	225	78.54	1	223	32	236	1.6e-31	103.8	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2904407946	159	85.8	8	154	15	153	4.6e-11	37.6	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904407948	141	84.4	1	136	18	136	2.1e-08	27.7	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2904407949	194	86.86	57	186	13	131	1.3e-10	35.4	COG4319	Ketosteroid isomerase homolog	137
2904407950	181	86.52	45	179	18	139	3.0e-27	89.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2904407952	123	92.48	1	123	8	130	1.3e-20	68.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
2904407953	205	87.65	1	204	7	155	3.2e-23	76.7	COG0262	Dihydrofolate reductase	167
2904407954	151	95.65	1	151	1	154	8.4e-58	188.6	COG3837	Uncharacterized conserved protein, cupin superfamily	161
2904407955	158	99.32	4	142	2	146	1.3e-13	46.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2904407958	50	15.67	1	49	230	276	1.4e-19	64.9	COG4974	Site-specific recombinase XerD	300
2904407959	387	92.2	1	386	32	409	3.8e-69	227.4	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2904407960	403	97.8	1	402	9	409	4.3e-60	197.6	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2904407961	256	75.12	2	210	19	178	1.1e-08	26	COG2834	Outer membrane lipoprotein-sorting protein	211
2904407962	225	96.46	2	225	3	220	5.0e-84	275.3	COG1136	ABC-type lipoprotein export system, ATPase component	226
2904407964	473	10.19	344	392	134	155	7.7e-10	3.8	COG0778	Nitroreductase	207
2904407964	473	12.5	156	205	132	158	7.7e-10	4.2	COG0778	Nitroreductase	207
2904407964	473	13.43	96	148	28	56	7.7e-10	21.1	COG0778	Nitroreductase	207
2904407965	250	11.48	112	146	96	119	9.0e-14	4.3	COG3916	N-acyl-L-homoserine lactone synthetase	209
2904407965	250	28.23	17	92	13	71	9.0e-14	12.3	COG3916	N-acyl-L-homoserine lactone synthetase	209
2904407965	250	28.23	148	220	112	170	9.0e-14	26.1	COG3916	N-acyl-L-homoserine lactone synthetase	209
2904407966	219	72.73	10	187	20	171	5.6e-15	49.5	COG3916	N-acyl-L-homoserine lactone synthetase	209
2904407967	376	94.1	1	375	21	387	2.4e-51	169.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904407968	230	96.02	4	227	2	218	6.9e-84	274.8	COG1136	ABC-type lipoprotein export system, ATPase component	226
2904407969	386	97.65	16	384	1	498	7.7e-24	74.5	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2904407970	388	97.65	18	388	12	509	4.3e-30	96.9	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2904407974	244	63.48	2	225	35	213	8.6e-32	104.5	COG0421	Spermidine synthase	282
2904407975	684	98.35	1	682	7	723	0.0e+00	533	COG0480	Translation elongation factor EF-G, a GTPase	697
2904407977	600	97.51	4	459	6	474	1.4e-109	361.4	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2904407978	1253	18.27	1074	1249	527	644	0.0e+00	47.5	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2904407978	1253	68.73	40	501	1	444	0.0e+00	635.9	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2904407978	1253	97.15	488	810	1	307	1.4e-93	307	COG1984	Allophanate hydrolase subunit 2	314
2904407980	216	77.65	3	216	44	248	2.6e-60	198	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
2904407981	243	78.03	2	231	45	250	3.5e-33	109	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
2904407982	282	97.61	2	264	3	247	3.2e-89	292.9	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2904407983	274	95.74	18	273	7	253	7.0e-79	259.1	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2904407984	331	79.1	2	325	7	271	2.1e-55	182.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2904407988	594	97.49	20	461	7	395	1.8e-100	330.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2904407989	779	19.15	324	424	190	252	1.6e-84	19.2	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2904407989	779	55.85	462	764	15	162	6.2e-33	107.4	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2904407989	779	89.36	2	334	1	294	1.6e-84	257	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2904407990	378	99.75	1	378	1	393	0.0e+00	440.8	COG0183	Acetyl-CoA acetyltransferase	392
2904407991	572	97.36	25	572	4	556	0.0e+00	459.8	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2904407992	769	91.36	514	764	5	226	1.1e-33	109.3	COG1647	Esterase/lipase	243
2904407993	172	84.49	2	172	23	180	4.2e-54	177.2	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
2904407995	341	93.56	1	313	8	312	5.2e-54	177.8	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2904407996	629	98.67	13	615	2	594	0.0e+00	686.9	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
2904407997	142	96.62	1	142	1	143	2.8e-65	213	COG0102	Ribosomal protein L13	148
2904407998	130	96.24	1	130	6	133	1.5e-52	171.8	COG0103	Ribosomal protein S9	130
2904408000	82	40	4	63	54	91	1.7e-10	35.6	COG3514	Uncharacterized conserved protein, DUF4415 family	93
2904408002	78	88.75	1	78	8	78	5.1e-14	46.7	COG4710	Predicted DNA-binding protein with an HTH domain	80
2904408003	89	96.7	1	89	1	88	1.1e-26	87.4	COG2026	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system	90
2904408008	281	92.2	2	281	4	263	3.1e-51	166.8	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2904408009	318	95.95	11	312	2	309	3.4e-70	230.6	COG3458	Cephalosporin-C deacetylase or related acetyl esterase	321
2904408010	242	100	1	242	1	227	4.1e-89	292.5	COG4947	Esterase/lipase superfamily enzyme	227
2904408012	271	68.21	4	263	90	340	3.2e-14	47.8	COG0457	Tetratricopeptide (TPR) repeat	291
2904408014	583	92.34	83	579	36	517	0.0e+00	481	COG3540	Phosphodiesterase/alkaline phosphatase D	522
2904408017	189	79.03	15	176	39	185	1.6e-22	74.7	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2904408018	373	18.83	159	245	116	160	2.5e-19	24.2	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2904408018	373	28.03	50	137	50	116	2.5e-19	37.5	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2904408019	318	33.52	169	318	213	332	8.7e-22	13	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2904408019	318	39.39	12	173	22	162	8.7e-22	57.4	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2904408020	715	97.32	3	226	4	221	3.7e-45	148	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
2904408020	715	99.12	234	690	5	455	0.0e+00	466.2	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2904408021	137	95.49	8	136	3	129	2.1e-20	67.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2904408022	447	20.55	262	315	12	26	9.2e-08	2.5	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2904408022	447	41.1	90	215	34	63	9.2e-08	21.5	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2904408023	276	93.54	3	276	17	320	6.0e-55	180.9	COG0226	ABC-type phosphate transport system, periplasmic component	318
2904408024	292	92.99	3	290	13	304	1.3e-78	258.3	COG0573	ABC-type phosphate transport system, permease component	310
2904408025	290	93.54	5	285	14	288	1.5e-71	235.1	COG0581	ABC-type phosphate transport system, permease component	292
2904408026	288	96.85	33	288	7	252	2.2e-102	336	COG1117	ABC-type phosphate transport system, ATPase component	253
2904408027	101	74.17	1	101	9	97	3.9e-22	72.5	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2904408031	189	87.63	3	185	20	182	3.5e-40	131.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2904408035	171	16.41	4	139	49	113	6.1e-16	52.5	COG3328	Transposase (or an inactivated derivative)	379
2904408036	229	93.67	1	229	6	227	3.2e-26	86.5	COG0412	Dienelactone hydrolase	236
2904408045	246	81.25	162	235	10	74	6.1e-11	35.3	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2904408046	386	96.5	12	374	7	337	2.7e-16	51.7	COG3594	Fucose 4-O-acetylase or related acetyltransferase	343
2904408047	216	61.97	53	216	48	223	2.9e-27	90	COG2801	Transposase InsO and inactivated derivatives	232
2904408048	113	64.1	19	108	1	75	3.7e-15	50.6	COG2963	Transposase and inactivated derivatives	116
2904408050	213	36.36	1	169	12	107	5.9e-05	17.6	COG1729	Periplasmic TolA-binding protein (function unknown)	262
2904408054	98	28.46	8	93	4	40	2.0e-08	29.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2904408067	337	80.94	18	326	15	273	7.9e-68	223.4	COG0616	Periplasmic serine protease, ClpP class	317
2904408076	143	86.11	45	143	10	102	2.3e-03	12.2	COG3838	Type IV secretory pathway, VirB2 components (pilins)	108
2904408080	425	42.8	7	202	26	138	2.1e-05	18.6	COG1729	Periplasmic TolA-binding protein (function unknown)	262
2904408084	126	98.15	1	110	1	106	1.1e-33	110	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
2904408085	208	97.42	5	204	5	193	2.4e-58	190.8	COG2452	Predicted site-specific integrase-resolvase	193
2904408086	271	60.2	1	237	3	244	1.9e-39	129.7	COG0675	Transposase	364
2904408087	122	22.64	1	113	298	388	6.1e-38	124.9	COG0675	Transposase	364
2904408088	452	52.4	165	386	48	156	2.2e-05	18	COG2184	Fido, protein-threonine AMPylation domain	201
2904408091	212	88.74	2	199	6	202	3.4e-44	145	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
2904408092	237	60	5	232	79	204	9.9e-25	74.9	COG1059	Thermostable 8-oxoguanine DNA glycosylase	210
2904408095	83	80	10	75	12	67	1.4e-08	28.9	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2904408096	1162	13.35	545	709	329	393	4.5e-23	9.9	COG1061	Superfamily II DNA or RNA helicase	442
2904408096	1162	43.12	91	470	38	247	4.5e-23	64.5	COG1061	Superfamily II DNA or RNA helicase	442
2904408097	490	18.45	31	93	28	70	5.6e-17	23	COG3910	Predicted ATPase	233
2904408097	490	33.05	204	314	130	206	5.6e-17	31.1	COG3910	Predicted ATPase	233
2904408098	957	84.81	4	794	3	778	4.8e-108	356.1	COG1743	Adenine-specific DNA methylase, contains a Zn-ribbon domain	875
2904408102	250	98.8	1	247	2	248	2.2e-89	292.3	COG4422	Bacteriophage protein gp37	250
2904408103	111	52.31	5	106	7	74	1.3e-08	30.3	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2904408104	156	92.76	2	154	7	147	7.0e-43	140	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
2904408112	349	99.57	62	318	1	231	1.8e-48	159.1	COG3039	Transposase and inactivated derivatives, IS5 family	230
2904408113	142	14.37	3	137	588	710	5.4e-16	52.5	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904408115	1584	7.48	455	635	47	110	2.2e-45	10.3	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904408115	1584	10.4	360	462	15	103	2.2e-45	27	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904408115	1584	19.98	191	361	222	392	2.2e-45	4.4	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904408115	1584	26.87	634	846	33	262	2.2e-45	34.2	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904408115	1584	78.39	713	1415	39	709	2.2e-45	85.8	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904408117	168	31.54	7	158	127	202	1.4e-09	32.7	COG4083	Exosortase/Archaeosortase	239
2904408119	687	88.46	90	666	52	603	4.9e-55	179.9	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2904408123	112	36.1	6	105	131	217	5.2e-06	20.9	COG4083	Exosortase/Archaeosortase	239
2904408125	54	36.8	6	54	2	47	4.2e-07	24.9	COG3293	Transposase	124
2904408127	732	91.18	13	729	58	729	0.0e+00	451.2	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
2904408128	227	99.12	1	226	1	224	8.6e-76	248.5	COG2135	Putative SOS response-associated peptidase YedK	226
2904408129	188	64	12	182	29	156	3.2e-15	50.1	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
2904408133	278	97.2	1	277	3	245	1.7e-49	159.1	COG4422	Bacteriophage protein gp37	250
2904408134	97	95	1	97	5	99	1.2e-41	135.4	COG3657	Putative component of the toxin-antitoxin plasmid stabilization module	100
2904408135	103	96	1	100	4	99	2.2e-40	131	COG3636	DNA-binding prophage protein	100
2904408136	49	47.56	1	48	17	55	2.4e-04	16.3	COG4423	Uncharacterized protein	81
2904408137	561	61.8	9	144	11	120	5.7e-46	57.7	COG3617	Prophage antirepressor	176
2904408137	561	63.48	279	414	5	117	5.7e-46	90.8	COG3617	Prophage antirepressor	176
2904408137	561	81.82	152	265	9	98	1.1e-29	96.3	COG3561	Phage anti-repressor protein	110
2904408141	328	54.67	109	314	42	123	2.8e-04	15.4	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2904408144	229	95.52	16	79	3	66	2.8e-14	46.7	COG1278	Cold shock protein, CspA family	67
2904408145	85	55.81	1	70	3	50	5.3e-09	30.1	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
2904408146	140	97.73	1	140	2	130	6.2e-23	75.4	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
2904408152	525	83.25	82	489	64	391	6.4e-71	233.9	COG0642	Signal transduction histidine kinase	336
2904408153	434	93.82	1	422	25	419	4.6e-77	253.9	COG2124	Cytochrome P450	411
2904408154	674	96.23	2	674	31	795	4.4e-50	165.1	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904408155	317	35.78	16	106	2	84	1.5e-25	12.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904408155	317	52.59	140	303	2	123	1.5e-25	70.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904408158	955	85.58	2	589	91	743	1.4e-125	414	COG0209	Ribonucleotide reductase alpha subunit	696
2904408163	150	56.38	31	135	46	129	3.9e-05	17.1	COG3120	Macrodomain Ter protein organizer, MatP/YcbG family	149
2904408164	355	41.15	26	189	94	179	1.1e-06	12.6	COG0400	Predicted esterase	207
2904408165	140	21.79	4	140	67	105	5.6e-03	11.2	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
2904408166	199	60.3	22	171	79	198	2.2e-41	136.6	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2904408169	149	17.21	26	148	93	171	2.1e-06	20.5	COG4564	Signal transduction histidine kinase	459
2904408170	377	89.51	24	157	15	159	1.1e-08	28.8	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904408172	673	64.97	345	673	134	389	6.0e-65	214.8	COG0642	Signal transduction histidine kinase	336
2904408174	250	98.37	1	231	3	243	5.4e-68	223.2	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
2904408178	145	94.7	2	124	1	125	1.4e-34	113.4	COG0789	DNA-binding transcriptional regulator, MerR family	124
2904408179	168	10.24	43	91	49	78	2.6e-03	10.3	COG4120	ABC-type uncharacterized transport system, permease component	293
2904408179	168	11.6	95	164	41	74	2.6e-03	3	COG4120	ABC-type uncharacterized transport system, permease component	293
2904408180	273	59	1	177	17	157	3.7e-32	105.5	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2904408181	575	88.84	29	567	54	483	1.4e-129	427.6	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904408182	237	71.03	5	237	94	321	7.0e-57	187.3	COG3667	Uncharacterized protein involved in copper resistance	321
2904408183	221	93.21	7	220	5	210	2.0e-49	162.7	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
2904408184	215	96.85	20	213	5	219	1.1e-26	86.1	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2904408185	408	63.57	42	404	125	384	4.2e-30	100.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904408186	229	81.44	52	224	12	169	1.4e-16	55.6	COG0558	Phosphatidylglycerophosphate synthase	192
2904408187	249	48.95	11	209	44	160	7.2e-23	73.4	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2904408188	304	73.08	17	254	19	227	4.4e-31	102.1	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2904408189	479	85.03	104	479	56	390	2.0e-54	180.2	COG0642	Signal transduction histidine kinase	336
2904408190	240	98.28	5	235	2	229	1.3e-81	267.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904408191	165	93.12	1	163	7	155	3.7e-05	17	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
2904408192	320	57.35	11	305	21	180	1.2e-11	39.5	COG0500	SAM-dependent methyltransferase	257
2904408193	124	67.76	1	119	5	107	8.9e-21	68.9	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
2904408194	341	23.8	2	105	3	86	3.7e-35	16.6	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2904408194	341	63.17	103	340	126	348	3.7e-35	97.5	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2904408195	437	81.82	220	431	4	183	4.0e-53	174	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
2904408195	437	96.94	1	190	7	196	3.8e-72	236.2	COG0807	GTP cyclohydrolase II	193
2904408196	145	95.04	1	139	5	138	1.3e-43	142.8	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2904408198	311	94.14	6	311	14	318	2.3e-07	24	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2904408200	410	59.72	213	398	77	205	2.2e-32	107.3	COG0811	Biopolymer transport protein ExbB/TolQ	216
2904408201	170	15.28	15	63	14	46	8.2e-25	14.5	COG0811	Biopolymer transport protein ExbB/TolQ	216
2904408201	170	43.06	67	169	107	199	8.2e-25	68.6	COG0811	Biopolymer transport protein ExbB/TolQ	216
2904408202	144	93.53	6	141	5	134	3.8e-31	102.1	COG0848	Biopolymer transport protein ExbD	137
2904408203	269	75.18	13	267	67	272	1.3e-30	101.3	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2904408204	178	45.52	19	95	79	144	7.0e-31	51.1	COG3212	Uncharacterized membrane protein YkoI	144
2904408204	178	53.79	89	171	67	144	7.0e-31	54.5	COG3212	Uncharacterized membrane protein YkoI	144
2904408206	454	29.98	2	223	43	200	1.6e-72	146.6	COG3511	Phospholipase C	527
2904408206	454	39.28	246	446	289	495	1.6e-72	89	COG3511	Phospholipase C	527
2904408207	497	96.99	1	269	1	258	1.4e-65	215.4	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
2904408208	430	93.39	11	428	11	434	2.4e-59	195.4	COG3259	Coenzyme F420-reducing hydrogenase, alpha subunit	441
2904408209	221	89.41	9	179	7	158	7.7e-06	19.5	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
2904408210	456	82.74	97	456	63	388	2.3e-52	173	COG0642	Signal transduction histidine kinase	336
2904408211	303	93.14	1	291	7	291	8.5e-61	197.5	COG3781	Predicted membrane chloride channel, bestrophin family	306
2904408212	61	89.23	1	61	8	65	3.1e-10	34.3	COG2879	Uncharacterized short protein YbdD, DUF466 family	65
2904408213	86	13.26	1	85	438	509	1.0e-03	12.1	COG1315	Uncharacterized conserved protein, DUF342 family	543
2904408214	523	89.52	2	517	17	520	5.3e-106	349.2	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2904408215	222	96.63	1	205	4	204	1.8e-59	195.3	COG0288	Carbonic anhydrase	207
2904408216	298	96.01	4	295	1	289	1.2e-39	131.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904408218	584	96.86	1	582	7	593	0.0e+00	544	COG0443	Molecular chaperone DnaK (HSP70)	579
2904408219	217	68.88	20	216	57	191	8.6e-18	57.6	COG0576	Molecular chaperone GrpE (heat shock protein)	193
2904408220	108	30.42	1	106	5	84	7.8e-16	53.5	COG2214	Curved DNA-binding protein CbpA, contains a DnaJ-like domain	237
2904408222	396	81.88	3	395	78	425	3.5e-106	350.3	COG0840	Methyl-accepting chemotaxis protein	408
2904408223	336	91.61	34	336	5	288	1.5e-107	353.4	COG0167	Dihydroorotate dehydrogenase	310
2904408224	235	37.02	1	111	3	89	2.0e-30	54.9	COG1891	Uncharacterized protein, UPF0264 family	235
2904408224	235	37.87	120	223	141	229	2.0e-30	43.9	COG1891	Uncharacterized protein, UPF0264 family	235
2904408225	192	89	1	180	14	191	3.0e-15	50.9	COG2457	Uncharacterized protein	199
2904408226	467	7.91	105	160	31	52	4.5e-11	2.8	COG0294	Dihydropteroate synthase	274
2904408226	467	74.46	227	432	71	277	4.5e-11	30.4	COG0294	Dihydropteroate synthase	274
2904408229	163	89.71	1	157	10	131	1.5e-08	28.9	COG1943	REP element-mobilizing transposase RayT	136
2904408230	335	94.2	103	314	3	197	8.2e-39	127.4	COG1300	Uncharacterized membrane protein SpoIIM, required for sporulation	207
2904408233	327	95.45	8	326	15	329	2.8e-98	323.3	COG0714	MoxR-like ATPase	329
2904408234	436	98.56	5	432	7	417	3.7e-76	251.1	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2904408235	268	35.29	76	267	178	279	3.0e-08	27.8	COG5473	Uncharacterized membrane protein	290
2904408236	242	85.8	12	164	5	155	6.5e-29	94.9	COG1714	Uncharacterized membrane protein YckC, RDD family	172
2904408237	71	24.73	7	69	100	145	5.1e-04	14.2	COG4186	Calcineurin-like phosphoesterase superfamily protein	186
2904408238	348	70.7	7	348	130	450	6.0e-65	213.8	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
2904408247	196	49.68	17	165	66	142	4.5e-20	66.1	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2904408248	735	99.73	2	734	2	733	0.0e+00	807.9	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
2904408249	236	88.16	1	232	19	219	8.0e-50	163.9	COG0705	Membrane associated serine protease, rhomboid family	228
2904408250	493	95.85	1	489	5	466	1.1e-33	110.8	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2904408251	792	98.74	1	792	10	792	0.0e+00	1243.5	COG3957	Phosphoketolase	793
2904408252	399	98.99	3	392	2	395	0.0e+00	487	COG0282	Acetate kinase	396
2904408254	48	24.04	2	48	3	52	5.0e-06	20.8	COG0288	Carbonic anhydrase	207
2904408255	216	54.9	22	207	63	219	1.0e-06	22.3	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2904408257	771	96.95	2	771	19	782	0.0e+00	579	COG4258	Predicted exporter	788
2904408258	395	99.03	1	395	3	412	3.9e-87	287	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2904408260	126	76.4	1	126	22	144	2.6e-29	96.5	COG4706	Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain	161
2904408261	377	99.43	13	362	2	350	0.0e+00	542.1	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
2904408262	326	97.06	1	66	3	68	2.9e-21	69.1	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
2904408262	326	97.33	65	326	5	259	2.9e-117	384.8	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
2904408264	201	99.48	1	197	1	191	2.9e-72	236.5	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
2904408265	94	6.13	46	94	250	274	4.7e-04	5.6	COG3748	Uncharacterized membrane protein	407
2904408265	94	12.5	1	72	260	310	4.7e-04	8.5	COG3748	Uncharacterized membrane protein	407
2904408266	345	74.69	22	288	44	285	4.1e-10	30.7	COG2988	Succinylglutamate desuccinylase	324
2904408267	475	15.18	178	251	125	180	9.1e-12	11.6	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
2904408267	475	36.04	42	188	5	137	9.1e-12	8.9	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
2904408267	475	36.31	296	466	222	355	9.1e-12	15.3	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
2904408270	507	85.63	1	277	41	320	2.1e-64	208.1	COG3344	Retron-type reverse transcriptase	328
2904408272	171	90.13	16	167	7	143	2.7e-30	99.6	COG3305	Uncharacterized membrane protein, DUF2068 family	152
2904408274	1078	26.33	14	294	11	277	0.0e+00	210.4	COG0841	Multidrug efflux pump subunit AcrB	1009
2904408274	1078	72.78	302	1075	276	1013	0.0e+00	560.6	COG0841	Multidrug efflux pump subunit AcrB	1009
2904408275	360	90.77	6	360	17	370	6.9e-51	167.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904408276	455	90.65	12	455	31	447	5.0e-71	234.1	COG1538	Outer membrane protein TolC	457
2904408277	173	95.29	3	169	5	166	2.4e-62	203.5	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
2904408278	226	98.63	1	226	1	216	2.2e-39	129.5	COG4094	Uncharacterized membrane protein	219
2904408280	333	100	7	333	1	325	3.4e-113	372.1	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
2904408281	401	98.77	3	398	4	405	4.5e-65	214.4	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
2904408282	950	99.35	5	930	5	921	0.0e+00	1311	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
2904408283	416	99.77	1	415	1	433	0.0e+00	482.8	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2904408284	805	64.72	424	781	134	388	2.0e-70	232.4	COG0642	Signal transduction histidine kinase	336
2904408285	204	97.03	3	203	5	200	6.7e-69	225.6	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2904408286	690	77.11	1	468	74	447	1.2e-45	149.7	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2904408286	690	97.32	458	683	5	222	2.8e-37	122.3	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
2904408287	234	96.89	1	229	6	254	6.5e-47	154.6	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2904408289	573	95.27	1	558	28	591	0.0e+00	468.5	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2904408291	847	64.84	701	842	7	124	1.3e-10	33.2	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2904408291	847	73.35	376	692	103	391	5.1e-76	251.2	COG0642	Signal transduction histidine kinase	336
2904408292	320	57.3	4	207	58	218	5.1e-17	56.8	COG2324	Uncharacterized membrane protein	281
2904408293	103	96.81	10	103	3	93	6.2e-34	110.5	COG3123	Uncharacterized conserved protein YaiE, UPF0345 family	94
2904408294	237	22.36	25	112	198	271	2.9e-34	65.8	COG0790	TPR repeat	292
2904408294	237	27.79	96	226	100	191	2.9e-34	58.3	COG0790	TPR repeat	292
2904408295	333	100	9	332	1	331	6.7e-104	342.1	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2904408296	163	54.67	10	152	35	116	3.7e-07	24.9	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2904408297	237	94.71	3	235	11	225	7.8e-52	170.4	COG1451	Predicted metal-dependent hydrolase	223
2904408298	165	94.74	17	164	7	150	9.1e-36	117.2	COG0782	Transcription elongation factor, GreA/GreB family	151
2904408299	603	89.07	382	581	14	176	2.2e-26	86.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904408299	603	93.77	6	258	6	246	1.1e-66	218.2	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2904408299	603	94.48	258	389	9	162	3.8e-07	23.9	COG0517	CBS domain	117
2904408300	401	98.68	5	383	4	378	1.0e-108	357.7	COG0763	Lipid A disaccharide synthetase	381
2904408301	365	98.93	2	365	3	373	0.0e+00	449.9	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2904408302	311	96.58	1	311	1	339	4.5e-55	181.1	COG0673	Predicted dehydrogenase	342
2904408303	262	84.62	1	247	4	223	5.3e-79	259.3	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
2904408304	287	95.67	1	287	13	299	2.9e-116	382.3	COG4974	Site-specific recombinase XerD	300
2904408305	116	95.08	1	116	6	121	8.6e-50	162.2	COG0335	Ribosomal protein L19	115
2904408306	249	99.18	1	244	1	242	1.4e-100	329.6	COG0336	tRNA G37 N-methylase TrmD	240
2904408307	166	94.83	2	166	8	172	1.8e-51	168.4	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
2904408308	87	88.89	1	87	1	80	4.5e-35	113.9	COG0228	Ribosomal protein S16	87
2904408310	68	84.93	1	68	1	62	1.1e-34	112.9	COG1551	sRNA-binding carbon storage regulator CsrA	73
2904408311	409	99.77	1	403	1	442	0.0e+00	486.5	COG0527	Aspartokinase	447
2904408312	866	99.21	1	865	6	880	0.0e+00	1151.9	COG0013	Alanyl-tRNA synthetase	879
2904408313	146	84.3	1	146	19	163	3.8e-36	118.9	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
2904408314	349	98.28	1	282	5	290	0.0e+00	433.2	COG0468	RecA/RadA recombinase	279
2904408315	191	98.9	8	180	2	181	9.4e-38	124.1	COG1514	2'-5' RNA ligase	180
2904408316	164	95.09	2	164	6	160	3.7e-60	196.4	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
2904408317	854	99.53	6	851	4	853	0.0e+00	1058.4	COG0249	DNA mismatch repair ATPase MutS	843
2904408318	239	85.14	6	238	36	247	8.2e-28	91.8	COG1651	Protein-disulfide isomerase	244
2904408319	453	48.26	4	220	3	196	2.9e-101	158.6	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
2904408319	453	67.66	202	453	130	401	2.9e-101	181.1	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
2904408320	395	99.22	1	394	1	383	0.0e+00	537.7	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
2904408321	320	95.27	1	266	11	272	1.2e-49	163.7	COG0575	CDP-diglyceride synthetase	265
2904408322	262	92.46	2	241	19	251	3.0e-97	319.1	COG0020	Undecaprenyl pyrophosphate synthase	245
2904408323	185	98.4	1	185	4	187	2.8e-80	262.5	COG0233	Ribosome recycling factor	187
2904408324	240	99.16	3	238	2	237	2.4e-93	306.4	COG0528	Uridylate kinase	238
2904408325	294	99.33	1	293	2	296	1.9e-118	389.3	COG0264	Translation elongation factor EF-Ts	296
2904408326	261	93.75	1	260	6	245	9.8e-104	340.2	COG0052	Ribosomal protein S2	252
2904408328	267	99.68	1	253	1	309	1.6e-96	317.4	COG0024	Methionine aminopeptidase	255
2904408329	887	98.39	13	887	8	860	0.0e+00	1000.4	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
2904408331	368	97.3	1	364	1	360	0.0e+00	434.1	COG0686	Alanine dehydrogenase	371
2904408334	333	97.19	1	328	8	318	1.3e-90	298	COG0837	Glucokinase	320
2904408335	160	83.22	7	159	24	147	1.1e-52	172	COG3019	Uncharacterized conserved protein	149
2904408336	141	97.81	1	138	2	135	2.6e-43	141.5	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
2904408338	223	86.4	3	222	24	239	2.3e-43	142.6	COG3719	Ribonuclease I	249
2904408340	206	79.43	1	204	6	171	8.2e-20	66.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904408342	173	54.72	2	171	85	223	8.4e-30	97.6	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2904408343	542	83.83	3	523	29	505	4.4e-83	273.7	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2904408344	218	54.81	130	218	40	113	4.0e-45	64.1	COG2863	Cytochrome c553	121
2904408344	218	77.78	3	140	19	123	4.0e-45	85	COG2863	Cytochrome c553	121
2904408345	358	91.23	2	336	25	357	8.2e-113	371.2	COG1858	Cytochrome c peroxidase	364
2904408346	744	68.33	250	738	190	642	2.8e-108	356.7	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2904408347	81	20.41	4	20	23	32	2.7e-02	5.2	COG1996	DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger	49
2904408347	81	48.98	28	58	6	29	2.7e-02	4.5	COG1996	DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger	49
2904408348	278	89.35	4	250	23	257	2.7e-51	168.6	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2904408349	183	68.7	1	183	65	233	9.3e-68	222.4	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2904408350	124	91.74	14	124	10	109	1.8e-16	54.3	COG3584	3D (Asp-Asp-Asp) domain	109
2904408352	484	49.01	195	436	154	302	9.3e-14	45.5	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2904408353	219	32.7	4	211	19	139	4.1e-07	20	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2904408355	109	26.44	1	96	121	207	2.4e-22	74.2	COG0724	 RNA recognition motif (RRM) domain	306
2904408356	294	96.35	1	288	2	291	1.3e-30	101	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2904408357	1010	5.13	20	70	39	72	6.1e-120	2.2	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2904408357	1010	55.37	441	567	108	241	4.0e-37	66	COG2202	PAS domain	232
2904408357	1010	58.26	156	445	102	242	4.0e-37	55.8	COG2202	PAS domain	232
2904408357	1010	64.4	535	1007	217	643	6.1e-120	395.8	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2904408358	433	49.35	214	421	9	197	3.5e-15	11.6	COG0477	MFS family permease	338
2904408358	433	60.57	12	248	8	239	3.5e-15	41.2	COG0477	MFS family permease	338
2904408359	448	99.56	3	448	3	454	0.0e+00	552.8	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
2904408360	545	93.97	254	545	2	297	8.2e-101	331.7	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
2904408361	74	78.26	1	74	6	77	3.3e-35	113.1	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
2904408362	65	17.5	2	57	14	55	8.8e-04	13	COG1646	Heptaprenylglyceryl phosphate synthase	240
2904408363	441	100	5	437	1	433	0.0e+00	595.9	COG0593	Chromosomal replication initiation ATPase DnaA	408
2904408364	367	100	1	367	1	365	2.3e-114	376.7	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
2904408365	356	99.72	1	355	1	362	1.0e-94	311.8	COG1195	Recombinational DNA repair ATPase RecF	363
2904408366	805	99.53	3	805	4	641	0.0e+00	990.2	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
2904408367	269	94.79	1	266	6	278	2.2e-95	313.2	COG0682	Prolipoprotein diacylglyceryltransferase	287
2904408368	298	99.27	2	298	3	273	8.8e-95	311.3	COG0207	Thymidylate synthase	268
2904408369	616	63.96	225	592	138	389	1.0e-66	220.6	COG0642	Signal transduction histidine kinase	336
2904408372	387	98.35	1	374	4	360	3.0e-112	369.8	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2904408373	162	99.41	2	160	1	169	2.3e-49	161.8	COG0262	Dihydrofolate reductase	167
2904408374	160	99.36	1	158	1	155	2.0e-67	220.1	COG0315	Molybdenum cofactor biosynthesis enzyme	157
2904408375	165	83.24	1	157	10	163	1.6e-38	126.5	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2904408377	298	98.18	10	297	5	274	2.0e-91	300.2	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
2904408378	275	98.85	72	270	1	172	1.4e-41	136.6	COG1076	DnaJ-domain-containing proteins 1	174
2904408379	160	98.18	1	160	4	165	4.4e-68	223	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
2904408380	762	99.44	3	749	2	714	0.0e+00	905.7	COG3256	Nitric oxide reductase large subunit	717
2904408381	225	91.86	1	217	15	217	1.0e-65	216	COG2846	Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains	221
2904408382	521	92.91	1	514	36	546	0.0e+00	577.9	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2904408385	489	98.48	1	485	1	453	6.1e-97	319.6	COG1538	Outer membrane protein TolC	457
2904408386	516	93.45	6	516	33	546	0.0e+00	567.3	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2904408387	242	99.59	1	240	1	245	2.4e-79	260.4	COG1385	16S rRNA U1498 N3-methylase RsmE	246
2904408388	448	98.66	1	448	3	443	0.0e+00	565.8	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2904408389	187	93.5	1	187	8	194	6.2e-19	61.9	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
2904408390	285	96.93	1	284	9	292	3.8e-98	322.6	COG0685	5,10-methylenetetrahydrofolate reductase	291
2904408391	472	99.52	9	464	3	419	0.0e+00	664.4	COG0499	S-adenosylhomocysteine hydrolase	420
2904408393	389	98.97	1	386	3	387	0.0e+00	637.5	COG0192	S-adenosylmethionine synthetase	388
2904408394	161	29.33	77	152	45	66	3.1e-03	11	COG4064	Tetrahydromethanopterin S-methyltransferase, subunit G	75
2904408395	182	99.42	1	175	1	171	1.1e-70	231.2	COG0221	Inorganic pyrophosphatase	171
2904408396	280	100	2	280	1	279	3.5e-113	371.5	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
2904408397	101	84.62	1	99	6	93	1.7e-26	86.4	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
2904408398	92	100	1	92	1	94	1.5e-29	96.6	COG3549	Plasmid maintenance system killer protein	94
2904408399	148	8.41	22	139	15	79	8.7e-03	8.4	COG4993	Glucose dehydrogenase	773
2904408400	406	95.47	1	366	5	362	0.0e+00	558.3	COG5008	Tfp pilus assembly protein, ATPase PilU	375
2904408402	1393	22.16	1265	1373	3	80	3.1e-57	21.8	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2904408402	1393	40.51	671	718	41	72	2.4e-01	4.2	COG3074	Cell division protein ZapB, interacts with FtsZ	79
2904408402	1393	57.95	2	217	143	346	3.1e-57	166.7	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2904408402	1393	64.56	718	782	27	77	2.4e-01	4.8	COG3074	Cell division protein ZapB, interacts with FtsZ	79
2904408402	1393	65.48	821	1248	132	389	5.7e-59	195.1	COG0642	Signal transduction histidine kinase	336
2904408402	1393	98.89	228	494	2	268	9.1e-74	241.7	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2904408404	625	80.71	237	622	55	351	4.1e-12	41.4	COG0457	Tetratricopeptide (TPR) repeat	291
2904408405	326	46.13	53	321	126	310	4.5e-17	56.4	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
2904408407	307	60.43	8	298	151	402	1.4e-42	140.4	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2904408408	382	90.24	2	382	36	414	1.2e-130	430.2	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
2904408410	174	98.14	11	168	1	158	3.6e-60	196.4	COG3265	Gluconate kinase	161
2904408411	447	93.53	1	447	24	457	1.0e-104	345.1	COG4325	Uncharacterized membrane protein	464
2904408412	245	94.82	1	245	8	245	1.8e-63	209.3	COG4700	Uncharacterized protein	251
2904408413	199	59.09	3	197	126	307	3.5e-70	231.1	COG1715	Restriction endonuclease Mrr	308
2904408414	1026	93	255	1020	63	899	0.0e+00	562.2	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
2904408415	279	94.1	1	279	9	263	1.6e-64	212.5	COG4279	Uncharacterized conserved protein, contains Zn finger domain	266
2904408417	225	38.04	19	221	126	265	3.3e-04	14.1	COG0457	Tetratricopeptide (TPR) repeat	291
2904408419	258	45.54	1	211	83	179	1.9e-07	22.4	COG2834	Outer membrane lipoprotein-sorting protein	211
2904408420	408	98.54	1	408	6	409	9.0e-79	259.2	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2904408421	238	96.9	3	230	2	220	1.6e-82	270.4	COG1136	ABC-type lipoprotein export system, ATPase component	226
2904408422	223	80.97	8	222	50	266	1.5e-19	64.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904408423	269	98.88	20	267	2	266	4.4e-52	171.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904408424	199	19.57	5	198	238	309	5.2e-07	24.1	COG0457	Tetratricopeptide (TPR) repeat	291
2904408425	510	10.49	68	159	2	48	1.4e-09	22.9	COG1232	Protoporphyrinogen oxidase	444
2904408425	510	17.86	240	497	333	412	1.4e-09	7.1	COG1232	Protoporphyrinogen oxidase	444
2904408426	105	68.92	2	103	40	141	3.0e-14	47.1	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2904408427	143	26.35	1	50	4	42	1.3e-06	7.9	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2904408427	143	52.03	57	143	62	138	1.3e-06	13.3	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2904408428	395	99.03	1	391	2	411	2.4e-61	201.9	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2904408429	245	77.31	4	244	19	219	1.6e-16	54.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2904408430	247	99.25	1	246	2	267	5.6e-80	263.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904408431	402	99.52	1	401	2	413	1.3e-125	413.8	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2904408432	89	96.3	1	86	1	78	8.9e-16	52.2	COG0236	Acyl carrier protein	80
2904408433	646	95.81	1	612	15	631	0.0e+00	491	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
2904408434	287	69.41	37	285	88	323	2.2e-16	53.8	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
2904408435	273	92.65	47	248	2	190	7.8e-20	65.5	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
2904408437	382	92.52	27	373	27	360	8.9e-60	196.8	COG3177	Fic family protein	348
2904408439	1007	99.5	32	1004	4	999	0.0e+00	879.9	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
2904408440	407	33.33	50	209	270	404	2.5e-62	81.2	COG0732	Restriction endonuclease S subunit	391
2904408440	407	47.9	212	404	212	405	2.5e-62	123	COG0732	Restriction endonuclease S subunit	391
2904408441	527	99.04	2	526	3	520	0.0e+00	498.2	COG0286	Type I restriction-modification system, DNA methylase subunit	489
2904408442	110	66.67	2	110	36	131	2.1e-28	93.2	COG4190	Predicted transcriptional regulator	144
2904408449	199	86.6	3	194	4	171	5.7e-28	92.6	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
2904408450	305	89.02	1	305	17	324	3.6e-78	257.5	COG1171	Threonine dehydratase	347
2904408452	336	38.96	29	182	140	296	2.7e-48	71.7	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904408452	336	57.07	110	336	89	318	2.7e-48	99.8	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904408454	91	7.63	10	52	184	203	1.0e-02	2.5	COG3483	Tryptophan 2,3-dioxygenase (vermilion)	262
2904408454	91	9.16	49	90	203	226	1.0e-02	8.4	COG3483	Tryptophan 2,3-dioxygenase (vermilion)	262
2904408457	207	92.78	1	186	12	191	1.1e-53	176.5	COG0558	Phosphatidylglycerophosphate synthase	192
2904408458	612	99.5	8	607	3	597	0.0e+00	764.8	COG0322	Excinuclease UvrABC, nuclease subunit	581
2904408459	426	96.69	1	426	11	448	7.3e-99	325.8	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
2904408460	386	95.82	2	384	4	370	1.3e-16	55.2	COG0477	MFS family permease	338
2904408461	716	68.58	1	193	42	220	9.1e-30	97.5	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2904408461	716	95.77	198	712	11	554	1.8e-81	268.2	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2904408462	332	97.73	31	317	6	306	1.5e-41	136.4	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2904408463	768	98.85	1	768	9	781	0.0e+00	1092.4	COG2183	Transcriptional accessory protein Tex/SPT6	780
2904408464	892	8.83	637	707	194	249	0.0e+00	6.8	COG1042	Acyl-CoA synthetase (NDP forming)	598
2904408464	892	54.94	696	889	48	136	1.9e-08	25.8	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904408464	892	99.37	3	634	3	632	0.0e+00	695	COG1042	Acyl-CoA synthetase (NDP forming)	598
2904408465	398	97.89	5	398	6	376	1.5e-84	278.4	COG1454	Alcohol dehydrogenase, class IV	377
2904408466	204	98.08	1	203	3	206	3.2e-55	181.1	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2904408467	219	94.79	13	218	4	203	5.9e-75	245.6	COG2518	Protein-L-isoaspartate O-methyltransferase	209
2904408468	251	99.61	1	246	1	255	5.3e-89	292.4	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
2904408469	308	95.59	57	308	11	270	2.6e-56	185.6	COG0428	Zinc transporter ZupT	266
2904408470	235	92.19	27	213	8	184	4.8e-43	141.2	COG2119	Putative Ca2+/H+ antiporter, TMEM165/GDT1 family	190
2904408471	67	50	1	63	15	56	1.7e-06	22.5	COG5450	Transcription regulator of the Arc/MetJ class	84
2904408472	502	100	3	501	1	388	1.7e-100	326.3	COG1344	Flagellin and related hook-associated protein FlgL	360
2904408473	129	65.83	14	129	42	120	8.2e-23	75.4	COG1334	Uncharacterized conserved protein, FlaG/YvyC family	120
2904408474	683	98.8	1	676	3	494	4.4e-94	309.1	COG1345	Flagellar capping protein FliD	483
2904408475	128	86.36	1	122	13	126	3.3e-35	115.2	COG1516	Flagellin-specific chaperone FliS	132
2904408477	274	94.72	3	273	15	265	2.7e-76	251	COG4137	ABC-type uncharacterized transport system, permease component	265
2904408478	452	99.34	1	452	1	449	0.0e+00	626.3	COG0541	Signal recognition particle GTPase	451
2904408479	307	99.03	1	307	1	306	9.1e-69	226.3	COG1893	Ketopantoate reductase	307
2904408480	232	55.89	1	232	94	335	1.2e-42	140.8	COG0593	Chromosomal replication initiation ATPase DnaA	408
2904408481	199	98.59	1	195	3	212	7.0e-37	121.7	COG0655	Multimeric flavodoxin WrbA	207
2904408482	115	98.29	1	115	1	115	1.4e-38	126	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2904408483	152	92.64	1	123	13	163	2.3e-21	71	COG0517	CBS domain	117
2904408484	267	95.97	1	266	9	270	1.9e-81	267.7	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
2904408485	346	36.85	4	180	23	179	1.2e-82	174	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
2904408485	346	38.73	172	345	253	417	1.2e-82	97	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
2904408486	158	98.11	2	158	1	156	8.4e-69	225	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
2904408487	237	97.41	6	235	3	228	1.6e-74	244.2	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
2904408488	118	73.73	1	93	26	112	5.8e-26	84.9	COG2919	Cell division protein FtsB	117
2904408489	427	99.53	1	426	1	423	0.0e+00	665.4	COG0148	Enolase	423
2904408490	273	96.77	1	273	6	275	3.0e-129	424.3	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
2904408491	545	99.81	2	542	1	534	0.0e+00	836.9	COG0504	CTP synthase (UTP-ammonia lyase)	533
2904408493	454	91.88	7	304	24	306	9.6e-68	222.5	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
2904408494	321	99.05	2	318	3	316	0.0e+00	502.4	COG0825	Acetyl-CoA carboxylase alpha subunit	317
2904408495	239	98.31	4	239	3	235	1.8e-45	149.6	COG0412	Dienelactone hydrolase	236
2904408496	496	98.56	1	488	7	485	0.0e+00	578.8	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
2904408498	427	73.49	40	371	2	317	1.5e-25	84.3	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2904408499	106	62.22	2	106	30	113	1.3e-16	55.2	COG2863	Cytochrome c553	121
2904408501	114	21.25	1	45	5	38	1.1e+00	4.6	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
2904408501	114	30.63	31	87	107	155	1.1e+00	10.5	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
2904408503	113	97.44	1	113	2	115	9.0e-33	107.3	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2904408504	376	96.41	1	376	14	416	1.1e-101	335.3	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2904408505	284	95.82	1	284	9	283	9.9e-98	321.2	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2904408506	76	88.89	1	76	6	77	1.4e-27	89.8	COG1722	Exonuclease VII small subunit	81
2904408507	300	92.07	5	300	3	304	1.2e-77	254.9	COG0142	Geranylgeranyl pyrophosphate synthase	322
2904408508	639	99.2	5	624	2	623	0.0e+00	931.6	COG1154	Deoxyxylulose-5-phosphate synthase	627
2904408509	171	95.53	1	171	5	175	2.8e-56	184.1	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
2904408510	280	88.1	21	273	2	349	4.7e-32	104.6	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2904408511	397	11.02	319	387	178	203	8.4e-04	7.2	COG3637	Opacity protein and related surface antigens	199
2904408511	397	35.59	8	191	22	105	8.4e-04	3.8	COG3637	Opacity protein and related surface antigens	199
2904408512	154	32.92	30	151	129	235	1.6e-05	18	COG0226	ABC-type phosphate transport system, periplasmic component	318
2904408513	174	84.3	2	157	17	161	5.4e-24	79.3	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2904408514	239	92.92	1	222	6	202	2.9e-55	181.2	COG0560	Phosphoserine phosphatase	212
2904408515	76	92.5	1	76	5	78	6.6e-22	71.7	COG0425	TusA-related sulfurtransferase	78
2904408516	464	98.58	1	210	1	208	2.5e-59	193.7	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
2904408516	464	98.77	217	463	3	243	2.6e-103	338.8	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2904408517	144	87.79	1	138	17	167	1.7e-14	48	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2904408518	237	73.13	2	217	62	257	1.0e-34	114.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904408519	279	99.31	5	275	2	287	7.4e-22	67.8	COG0224	FoF1-type ATP synthase, gamma subunit	287
2904408520	495	90.28	6	487	11	465	0.0e+00	551	COG0056	FoF1-type ATP synthase, alpha subunit	504
2904408521	248	98.14	1	160	2	159	5.6e-22	72.6	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2904408522	88	87.5	6	81	10	79	3.7e-23	75.7	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
2904408523	226	90.87	1	220	22	250	9.2e-46	150.6	COG0356	FoF1-type ATP synthase, membrane subunit a	246
2904408524	90	67.24	2	88	15	92	3.4e-06	21.1	COG5336	FoF1-type ATP synthase assembly protein I	116
2904408525	132	82.96	1	131	18	129	1.0e-08	29.5	COG0355	FoF1-type ATP synthase, epsilon subunit	135
2904408526	449	98.7	4	447	2	458	0.0e+00	486.9	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2904408530	141	67.86	33	113	20	76	1.9e-04	15.5	COG3630	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit	84
2904408531	144	93.84	1	141	9	145	8.4e-36	117.4	COG0071	Molecular chaperone IbpA, HSP20 family	146
2904408532	1292	97.89	159	985	4	744	0.0e+00	884.2	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
2904408532	1292	99.18	1037	1292	2	243	2.9e-82	269.5	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
2904408533	224	13.7	3	58	7	53	6.4e-23	15.1	COG3317	Uncharacterized lipoprotein	342
2904408533	224	34.4	66	213	225	342	6.4e-23	58.8	COG3317	Uncharacterized lipoprotein	342
2904408534	291	97.32	1	291	4	294	3.8e-116	381.4	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2904408535	182	97.73	5	181	5	176	4.0e-44	144.7	COG2716	Glycine cleavage system regulatory protein	176
2904408536	158	97.45	1	156	3	155	3.3e-61	199.9	COG1225	Peroxiredoxin	157
2904408537	472	99.77	8	472	2	440	0.0e+00	546	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
2904408544	602	37.63	261	534	8	118	4.6e-07	24.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904408548	305	51.53	27	279	21	172	3.2e-13	44.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904408550	301	94.43	2	296	15	302	1.2e-25	84.7	COG4313	Uncharacterized conserved protein	304
2904408551	477	97.39	11	472	4	451	1.1e-112	371.5	COG1538	Outer membrane protein TolC	457
2904408552	202	10.05	173	202	13	33	2.1e-24	6.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904408552	202	50.24	1	172	9	113	2.1e-24	74.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904408553	340	92.61	1	340	14	339	4.9e-103	338.8	COG1566	Multidrug resistance efflux pump	352
2904408555	66	6.73	1	61	711	762	2.3e-03	10.5	COG1554	Trehalose and maltose hydrolase (possible phosphorylase)	772
2904408556	93	65.89	1	90	43	127	1.8e-18	60.9	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2904408558	409	96.85	1	409	12	411	1.3e-114	377.8	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2904408559	248	97.59	1	248	3	245	4.4e-51	168.5	COG0368	Cobalamin synthase	246
2904408560	191	87.08	1	186	2	183	5.4e-42	138.1	COG0406	Broad specificity phosphatase PhoE	208
2904408561	145	90.53	1	90	7	92	6.0e-29	94.1	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
2904408562	352	95.43	4	352	5	338	9.5e-99	324.8	COG2038	NaMN:DMB phosphoribosyltransferase	347
2904408563	173	97.71	1	170	4	174	2.5e-54	178	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
2904408564	491	99.18	2	484	2	483	0.0e+00	648.5	COG1492	Cobyric acid synthase	486
2904408565	223	91.63	33	222	11	196	2.1e-40	133.1	COG1865	Adenosylcobinamide amidohydrolase	200
2904408566	327	92.8	1	326	7	341	2.5e-61	201.8	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2904408567	305	96.25	1	305	5	312	1.5e-98	324.1	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
2904408568	268	81.17	2	261	52	314	3.7e-36	119.2	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2904408569	428	99.12	5	428	2	450	0.0e+00	438.2	COG1797	Cobyrinic acid a,c-diamide synthase	451
2904408570	246	91.67	10	212	2	199	2.5e-36	119.8	COG0778	Nitroreductase	207
2904408571	201	98.48	5	201	3	197	4.4e-75	246.1	COG2109	ATP:corrinoid adenosyltransferase	198
2904408573	619	99.02	3	616	5	611	0.0e+00	562.1	COG4206	Outer membrane cobalamin receptor protein	608
2904408575	264	78.95	4	252	35	259	6.8e-33	108.5	COG1864	DNA/RNA endonuclease G, NUC1	281
2904408586	165	77.96	1	149	36	180	4.9e-31	101.8	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
2904408587	137	25.48	1	59	5	57	1.4e-33	75.4	COG5588	Uncharacterized protein	207
2904408587	137	37.02	55	137	131	207	1.4e-33	36.3	COG5588	Uncharacterized protein	207
2904408588	227	73.68	25	227	54	221	5.5e-39	128.2	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2904408589	52	20.48	5	43	132	165	6.5e-04	13.9	COG1329	RNA polymerase-interacting regulator, CarD/CdnL/TRCF family	166
2904408590	230	93.37	14	229	10	192	7.6e-47	153.8	COG0693	Putative intracellular protease/amidase	188
2904408591	336	100	1	335	1	331	1.5e-84	278.6	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2904408593	239	99.14	3	238	2	231	1.2e-78	257.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904408594	941	40.89	285	798	356	602	9.6e-59	192	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2904408598	74	35.51	1	57	87	135	1.0e-06	23.5	COG4876	Uncharacterized protein YdaT	138
2904408599	356	76.81	1	110	4	56	1.0e-04	15.3	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2904408599	356	86.85	129	338	2	186	1.5e-22	73	COG2856	Zn-dependent peptidase ImmA, M78 family	213
2904408600	170	77.71	3	147	1	122	1.1e-03	13.2	COG2405	Predicted nucleic acid-binding protein, contains PIN domain	157
2904408601	998	93.51	6	996	18	953	0.0e+00	629.8	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
2904408602	471	98.77	18	432	5	404	3.6e-40	132.1	COG0732	Restriction endonuclease S subunit	391
2904408603	791	21.03	672	790	275	384	0.0e+00	8.1	COG0286	Type I restriction-modification system, DNA methylase subunit	489
2904408603	791	99.43	2	659	3	522	0.0e+00	449.1	COG0286	Type I restriction-modification system, DNA methylase subunit	489
2904408605	584	80.78	263	571	13	302	2.3e-65	214.7	COG3472	Uncharacterized protein	342
2904408606	69	50.6	9	68	3	44	2.1e-06	22.1	COG3905	Predicted transcriptional regulator	83
2904408607	244	51.69	18	231	26	86	2.7e-03	12.1	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2904408611	464	97.64	2	464	6	461	0.0e+00	464	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904408612	123	85.82	1	117	19	133	2.9e-19	63.9	COG3335	Transposase	132
2904408614	153	23.09	10	151	19	148	3.5e-27	89.1	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2904408616	361	88.21	3	345	35	378	1.4e-34	114	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904408617	1058	99.8	1	1030	2	1013	0.0e+00	964.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2904408618	478	94.13	17	478	18	450	2.0e-77	255.3	COG1538	Outer membrane protein TolC	457
2904408619	503	98.77	3	497	5	484	0.0e+00	586	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
2904408624	1218	3.27	3	42	13	43	1.5e-10	5.2	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2904408624	1218	59.96	185	925	209	777	1.5e-10	29	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2904408626	829	98.84	10	780	5	768	0.0e+00	649.2	COG1554	Trehalose and maltose hydrolase (possible phosphorylase)	772
2904408627	197	95.22	5	197	5	203	6.3e-48	157.5	COG0406	Broad specificity phosphatase PhoE	208
2904408628	241	93.48	19	240	7	221	5.5e-20	66.1	COG1266	Membrane protease YdiL, CAAX protease family	226
2904408629	238	85	9	146	11	146	4.1e-12	40.3	COG4244	Uncharacterized membrane protein	160
2904408631	176	35.88	5	150	56	116	1.3e-03	6.2	COG4803	Uncharacterized membrane protein	170
2904408632	383	98.22	7	371	6	391	4.1e-49	161.4	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2904408633	168	83.12	1	167	9	141	1.0e-07	25.7	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
2904408634	721	95.36	9	696	30	645	0.0e+00	478.4	COG3408	Glycogen debranching enzyme (alpha-1,6-glucosidase)	641
2904408635	222	67.46	108	216	40	124	4.2e-32	105.3	COG3245	Cytochrome c5	126
2904408636	224	86.85	12	222	26	210	2.9e-47	154.1	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2904408637	542	91.21	13	540	6	524	0.0e+00	622.9	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2904408638	317	81.89	2	225	21	228	1.1e-54	179.3	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2904408641	187	57.32	28	177	62	155	9.3e-08	26.1	COG2010	Cytochrome c, mono- and diheme variants	150
2904408643	456	94.76	39	456	20	399	3.6e-26	86.4	COG5557	Ni/Fe-hydrogenase 2 integral membrane subunit HybB	401
2904408644	1034	92.2	781	1030	8	196	3.7e-45	147.6	COG0437	Fe-S-cluster-containing dehydrogenase component	203
2904408647	396	15.19	235	386	860	1013	1.6e-128	158.7	COG0841	Multidrug efflux pump subunit AcrB	1009
2904408647	396	22.58	1	240	183	411	1.6e-128	273.5	COG0841	Multidrug efflux pump subunit AcrB	1009
2904408648	206	40.65	1	193	41	227	3.1e-33	109.7	COG1538	Outer membrane protein TolC	457
2904408650	859	93.58	4	846	48	951	0.0e+00	632	COG0474	Magnesium-transporting ATPase (P-type)	917
2904408651	264	77.25	7	169	41	186	1.4e-27	91.3	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
2904408652	241	75.63	10	236	15	225	3.0e-08	28.5	COG0500	SAM-dependent methyltransferase	257
2904408653	108	98.21	1	108	1	110	2.3e-23	77.2	COG0347	Nitrogen regulatory protein PII	112
2904408654	1022	99.51	1	1022	1	1025	0.0e+00	1191.9	COG3696	Cu/Ag efflux pump CusA	1027
2904408655	401	95.64	12	391	8	380	8.4e-42	137.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904408656	454	84.52	4	452	57	389	1.9e-57	188.9	COG0642	Signal transduction histidine kinase	336
2904408657	221	98.71	1	219	1	229	6.0e-78	255.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2904408658	231	95.83	1	179	5	188	1.6e-40	133.1	COG3658	Cytochrome b	192
2904408660	134	31.1	4	102	35	85	3.4e-04	15.2	COG2010	Cytochrome c, mono- and diheme variants	150
2904408661	78	75.58	2	76	3	67	3.3e-16	54	COG3831	WGR domain, predicted DNA-binding domain in MolR	85
2904408662	300	15.75	54	270	318	501	1.5e-04	13.5	COG1196	Chromosome segregation ATPase	1163
2904408664	555	87	210	549	26	286	3.3e-30	97.8	COG4974	Site-specific recombinase XerD	300
2904408666	164	43.14	8	146	6	137	2.6e-37	123.1	COG1131	ABC-type multidrug transport system, ATPase component	293
2904408669	1310	10.33	1064	1254	765	854	0.0e+00	3.4	COG1643	HrpA-like RNA helicase	845
2904408669	1310	98.16	28	963	8	862	0.0e+00	932.2	COG1643	HrpA-like RNA helicase	845
2904408670	398	98.48	1	395	3	390	0.0e+00	602.6	COG0027	Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	394
2904408671	204	47.19	14	204	147	289	4.2e-41	136.2	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2904408672	289	95.85	1	279	8	284	6.2e-45	147.5	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
2904408673	192	98.45	1	192	2	192	1.3e-58	191.8	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
2904408674	178	96.65	14	176	6	178	1.3e-22	74.8	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
2904408675	63	98.25	1	56	1	56	1.4e-25	83.7	COG0333	Ribosomal protein L32	57
2904408676	323	93.81	1	321	17	334	9.3e-125	410.4	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
2904408677	321	99.39	2	321	2	325	0.0e+00	448.1	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2904408678	318	94.41	8	315	4	324	5.7e-80	263	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
2904408679	245	98.88	1	244	3	267	5.5e-77	253.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904408680	76	95.06	1	76	3	79	1.4e-30	99.7	COG0236	Acyl carrier protein	80
2904408681	413	99.52	2	413	2	413	0.0e+00	554.9	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2904408682	219	68.77	2	202	87	282	3.1e-41	136.4	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2904408683	345	96.22	8	344	9	339	1.9e-106	350.2	COG1559	Cell division protein YceG, involved in septum cleavage	342
2904408684	206	97.6	2	206	2	204	8.7e-74	242.1	COG0125	Thymidylate kinase	208
2904408685	337	12.99	240	333	287	362	1.3e-36	3.5	COG2812	DNA polymerase III, gamma/tau subunits	515
2904408685	337	25.47	16	178	27	175	1.3e-36	115.9	COG2812	DNA polymerase III, gamma/tau subunits	515
2904408686	118	98.29	1	118	3	117	2.3e-52	170.2	COG3215	Tfp pilus assembly protein PilZ	117
2904408687	254	80.9	25	244	36	196	2.3e-47	155.5	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2904408688	172	67.02	88	162	30	92	9.8e-02	7.1	COG1826	Sec-independent protein translocase protein TatA	94
2904408689	88	47.62	6	75	26	75	5.5e-05	17.9	COG4323	Uncharacterized protein	105
2904408692	449	84.77	14	432	56	389	3.1e-71	234.8	COG0642	Signal transduction histidine kinase	336
2904408693	225	83.58	25	91	3	58	5.6e-12	39.5	COG1278	Cold shock protein, CspA family	67
2904408693	225	89.36	121	223	5	88	4.8e-26	84.5	COG3326	Uncharacterized membrane protein YsdA, DUF1294 family	94
2904408694	130	79.45	2	128	30	145	3.1e-26	86.2	COG0071	Molecular chaperone IbpA, HSP20 family	146
2904408695	147	93.15	1	147	11	146	1.2e-33	110.4	COG0071	Molecular chaperone IbpA, HSP20 family	146
2904408697	229	91.87	36	227	15	206	7.2e-35	106.5	COG0400	Predicted esterase	207
2904408698	58	54.55	3	34	3	26	3.4e-04	13.4	COG5510	Predicted small secreted protein	44
2904408699	301	93.7	45	169	5	123	6.5e-43	84.3	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2904408699	301	93.7	176	297	6	124	6.5e-43	54.4	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2904408700	1719	6.99	1346	1385	375	411	8.1e-103	1.3	COG1640	4-alpha-glucanotransferase	520
2904408700	1719	99.24	170	732	1	525	8.1e-103	335.7	COG1640	4-alpha-glucanotransferase	520
2904408700	1719	99.66	750	1718	3	888	0.0e+00	1026	COG3280	Maltooligosyltrehalose synthase	889
2904408701	721	84.83	1	542	27	563	0.0e+00	539.8	COG0296	1,4-alpha-glucan branching enzyme	628
2904408702	421	94.87	28	404	14	401	1.7e-26	88	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904408704	608	64.29	481	608	7	123	5.4e-13	42.3	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2904408704	608	78.43	104	472	78	386	2.2e-71	235.9	COG0642	Signal transduction histidine kinase	336
2904408705	249	97.81	20	246	4	226	1.4e-102	336.3	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
2904408706	166	84.62	2	166	31	217	1.4e-27	91.4	COG2755	Lysophospholipase L1 or related esterase	216
2904408709	272	98.53	1	271	2	270	2.2e-82	270.9	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
2904408710	786	99.11	1	784	1	780	0.0e+00	891.9	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
2904408712	338	18.03	92	117	37	47	1.1e-03	7.9	COG0199	Ribosomal protein S14	61
2904408712	338	26.23	277	314	32	47	1.1e-03	3.3	COG0199	Ribosomal protein S14	61
2904408713	245	95.22	1	239	3	241	4.5e-73	240.1	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2904408714	247	94.19	1	247	12	254	6.0e-52	171	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2904408715	527	94.95	109	519	3	416	7.0e-118	388	COG0213	Thymidine phosphorylase	435
2904408716	297	94.03	1	296	8	306	1.4e-58	192.8	COG0462	Phosphoribosylpyrophosphate synthetase	314
2904408717	507	80.46	170	507	73	389	1.6e-62	206.8	COG0642	Signal transduction histidine kinase	336
2904408719	453	98.29	2	449	4	462	0.0e+00	537.8	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904408720	283	56.6	162	283	67	156	7.5e-31	61.5	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2904408720	283	91.19	1	159	12	156	7.5e-31	41	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2904408721	490	94.67	1	490	12	544	0.0e+00	456.2	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2904408722	189	90.78	9	189	6	192	2.2e-48	159.1	COG1335	Nicotinamidase-related amidase	205
2904408723	183	96.7	7	180	4	179	5.3e-47	154.3	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
2904408725	256	91.6	11	249	11	239	1.5e-51	169.6	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
2904408726	439	96.83	1	428	3	429	7.2e-121	398.4	COG0621	tRNA A37 methylthiotransferase MiaB	437
2904408727	410	29.61	236	317	9	69	2.5e-78	6.5	COG2715	Spore maturation protein SpmA (function unknown)	206
2904408727	410	99.03	2	216	2	205	2.5e-78	256.8	COG2715	Spore maturation protein SpmA (function unknown)	206
2904408728	800	23.18	50	301	33	248	0.0e+00	34.6	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2904408728	800	53.86	236	799	427	928	0.0e+00	787	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2904408729	319	98.37	4	316	2	303	4.6e-123	404.4	COG0492	Thioredoxin reductase	305
2904408730	56	92.73	4	56	2	52	2.2e-28	92.4	COG1773	Rubredoxin	55
2904408732	635	23	217	310	107	152	1.5e-09	5.4	COG0218	GTP-binding protein EngB required for normal cell division	200
2904408732	635	25.5	87	165	18	68	1.5e-09	24.3	COG0218	GTP-binding protein EngB required for normal cell division	200
2904408734	790	60.6	461	787	90	312	5.2e-16	53.5	COG0457	Tetratricopeptide (TPR) repeat	291
2904408735	98	26.38	4	98	3	88	9.9e-21	68.8	COG3547	Transposase	303
2904408740	545	99.51	5	458	3	407	1.9e-116	383.7	COG0644	Dehydrogenase (flavoprotein)	396
2904408741	317	99.06	2	315	2	316	1.2e-97	321.8	COG2025	Electron transfer flavoprotein, alpha subunit	313
2904408742	249	99.23	1	249	1	259	4.0e-87	286.1	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2904408743	387	99.45	10	370	2	361	1.0e-101	335	COG0349	Ribonuclease D	361
2904408744	527	92.94	340	518	2	159	1.9e-43	142.2	COG0645	Predicted kinase	170
2904408744	527	97.03	6	339	3	329	8.2e-108	354.3	COG2187	Aminoglycoside phosphotransferase family enzyme	337
2904408745	167	36.87	1	161	233	378	8.7e-39	127.7	COG3328	Transposase (or an inactivated derivative)	379
2904408746	226	53.54	4	226	16	227	9.3e-70	229.6	COG3328	Transposase (or an inactivated derivative)	379
2904408747	435	3.22	328	383	790	820	7.0e-04	6.8	COG4403	Lantibiotic modifying enzyme	963
2904408747	435	3.63	270	341	785	819	7.0e-04	0	COG4403	Lantibiotic modifying enzyme	963
2904408747	435	13.69	85	264	644	775	7.0e-04	1.2	COG4403	Lantibiotic modifying enzyme	963
2904408748	75	32.58	5	68	78	120	7.6e-04	14.2	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
2904408751	98	97	1	98	3	99	3.8e-42	136.9	COG3657	Putative component of the toxin-antitoxin plasmid stabilization module	100
2904408752	99	92	1	99	5	96	3.6e-38	124	COG3636	DNA-binding prophage protein	100
2904408753	131	78.79	1	102	3	106	1.1e-06	20.6	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
2904408754	366	94.53	58	354	2	243	4.0e-31	101.4	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
2904408759	188	12.68	6	88	14	39	3.4e-04	9.7	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
2904408759	188	23.9	120	177	131	179	3.4e-04	3	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
2904408760	221	66.51	5	215	17	155	4.0e-17	56.7	COG0400	Predicted esterase	207
2904408762	185	74.69	33	175	39	159	5.3e-17	56.4	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904408763	200	41.39	4	161	60	160	4.9e-15	49.7	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2904408765	139	92.09	2	139	6	133	1.7e-22	74.3	COG5331	Uncharacterized protein	139
2904408766	332	24.57	22	129	92	190	6.0e-67	79.5	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904408766	332	52.11	125	330	109	318	6.0e-67	147.6	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904408767	177	33.56	28	137	3	51	1.9e-05	17.9	COG3427	Carbon monoxide dehydrogenase subunit G	146
2904408768	479	98.11	1	478	9	474	0.0e+00	639.4	COG2925	Exonuclease I	475
2904408769	60	79.22	1	60	1	61	4.7e-16	52.8	COG2991	Uncharacterized protein	77
2904408770	406	99.27	1	406	4	410	0.0e+00	710.5	COG2871	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF	410
2904408771	202	100	1	202	1	198	8.1e-102	333.9	COG2209	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE	198
2904408772	221	99.52	1	208	2	208	2.4e-106	348.3	COG1347	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD	208
2904408773	308	95.83	29	308	7	259	1.1e-85	281.6	COG2869	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC	264
2904408774	401	99.5	4	397	3	402	0.0e+00	500.3	COG1805	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB	400
2904408775	452	99.78	2	452	2	447	0.0e+00	641.3	COG1726	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA	447
2904408778	266	67.58	2	258	22	244	1.5e-37	123.7	COG0714	MoxR-like ATPase	329
2904408779	300	91.53	9	297	8	277	9.5e-38	124.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904408780	119	76.38	10	118	8	104	1.8e-25	83.3	COG4451	Ribulose bisphosphate carboxylase small subunit	127
2904408781	473	99.53	7	461	2	428	0.0e+00	584.9	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
2904408784	292	99.01	1	290	3	303	2.9e-87	287.3	COG2264	Ribosomal protein L11 methylase PrmA	300
2904408785	448	99.11	1	448	1	446	0.0e+00	675.2	COG0439	Biotin carboxylase	449
2904408786	149	99.32	6	149	1	146	2.6e-43	142.7	COG0511	Biotin carboxyl carrier protein	140
2904408787	147	97.26	2	147	2	143	4.5e-66	215.3	COG0757	3-dehydroquinate dehydratase	146
2904408788	174	88.67	5	163	13	145	4.2e-16	53.8	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2904408789	749	19.64	17	167	36	155	0.0e+00	74.7	COG4232	Thiol:disulfide interchange protein	569
2904408789	749	93.94	156	749	36	609	0.0e+00	595.9	COG4232	Thiol:disulfide interchange protein	569
2904408790	109	95.19	3	105	2	100	1.4e-34	112.3	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
2904408791	142	88.2	4	142	5	146	5.5e-39	127.5	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
2904408792	471	87.67	3	71	5	68	2.7e-17	56.7	COG2608	Copper chaperone CopZ	71
2904408792	471	92.8	117	353	7	225	1.5e-44	146	COG2836	Sulfite exporter TauE/SafE	232
2904408794	416	64.88	122	414	144	409	7.4e-27	85.9	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2904408795	226	96.9	1	225	1	219	7.2e-69	225.7	COG1136	ABC-type lipoprotein export system, ATPase component	226
2904408797	167	78.98	5	166	25	163	7.6e-20	65.2	COG4314	Nitrous oxide reductase accessory protein NosL	176
2904408798	178	84.71	27	167	4	136	5.4e-15	49.4	COG1225	Peroxiredoxin	157
2904408799	477	68.75	12	157	34	154	4.5e-12	38	COG4314	Nitrous oxide reductase accessory protein NosL	176
2904408800	465	78.93	48	285	52	242	5.1e-43	141.9	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
2904408801	269	93.82	1	258	11	253	3.6e-59	194.4	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2904408802	267	99.61	8	265	1	253	2.9e-100	328.9	COG0134	Indole-3-glycerol phosphate synthase	254
2904408803	342	99.12	1	337	3	339	0.0e+00	433.7	COG0547	Anthranilate phosphoribosyltransferase	338
2904408804	195	97.91	2	195	3	189	3.4e-84	275.3	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
2904408805	496	98.5	18	490	4	463	0.0e+00	559.6	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2904408806	226	96.85	4	225	6	220	3.6e-55	181.6	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2904408807	231	98.64	1	228	2	218	5.8e-91	297.8	COG0036	Pentose-5-phosphate-3-epimerase	220
2904408808	273	93.44	72	269	13	183	4.5e-53	173.7	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904408809	557	64.04	32	461	3	303	3.9e-48	158.9	COG0515	Serine/threonine protein kinase	384
2904408810	904	94.8	1	316	9	318	1.2e-90	298	COG0258	5'-3' exonuclease	310
2904408810	904	99.83	304	904	2	597	0.0e+00	840.7	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
2904408815	149	90.85	15	148	4	132	4.4e-12	40.3	COG3431	Uncharacterized membrane protein, DUF373 family	142
2904408817	82	68.6	10	81	11	69	3.1e-09	30.6	COG3831	WGR domain, predicted DNA-binding domain in MolR	85
2904408818	87	90.91	35	87	2	51	9.0e-25	80.7	COG1773	Rubredoxin	55
2904408819	364	40.48	31	156	4	105	1.6e-70	75.8	COG0149	Triosephosphate isomerase	251
2904408819	364	57.14	204	360	103	246	1.6e-70	153.9	COG0149	Triosephosphate isomerase	251
2904408821	244	70.25	13	240	29	224	1.1e-10	36.3	COG0500	SAM-dependent methyltransferase	257
2904408822	296	87.83	1	274	15	216	9.9e-14	45.6	COG1266	Membrane protease YdiL, CAAX protease family	226
2904408825	197	48.8	50	188	116	237	3.8e-06	20.5	COG4424	LPS sulfotransferase NodH	250
2904408827	354	81.66	7	352	71	404	1.1e-40	134.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904408828	389	79.8	3	368	40	363	1.5e-08	27.7	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
2904408829	385	69.31	1	372	54	403	4.9e-36	118.7	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2904408830	465	93.98	1	447	20	456	3.9e-37	121.3	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2904408831	500	87.88	7	486	34	410	9.7e-19	57.6	COG3307	O-antigen ligase	424
2904408832	230	84.44	19	228	33	222	1.4e-62	204	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2904408835	361	72.61	1	352	126	475	2.4e-41	136.1	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2904408836	245	76.71	34	236	34	224	1.5e-26	87.3	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2904408838	431	96.09	1	412	13	405	1.1e-39	131.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904408839	383	87.68	1	379	28	383	3.6e-30	95.8	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
2904408840	374	96.09	4	370	14	406	1.3e-50	167.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904408841	345	60.07	38	303	12	172	4.3e-23	74	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2904408842	411	98.35	1	409	7	423	6.2e-67	220.4	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
2904408843	415	88.26	24	413	5	395	8.6e-62	196.7	COG3182	Uncharacterized iron-regulated membrane protein	442
2904408844	821	93.71	107	819	27	771	1.3e-111	368.6	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904408845	321	97.21	3	318	8	321	3.1e-90	296.5	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2904408846	176	87.1	3	172	19	180	2.0e-36	119.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2904408847	410	16.71	36	135	12	79	1.6e-33	36.3	COG1228	Imidazolonepropionase or related amidohydrolase	406
2904408847	410	44.96	174	407	221	403	1.6e-33	74	COG1228	Imidazolonepropionase or related amidohydrolase	406
2904408848	430	24.38	260	425	289	396	4.2e-62	74.3	COG3182	Uncharacterized iron-regulated membrane protein	442
2904408848	430	46.5	27	254	5	210	4.2e-62	131.2	COG3182	Uncharacterized iron-regulated membrane protein	442
2904408849	846	97.61	111	846	20	795	3.6e-113	374	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904408850	320	94.43	3	320	14	318	2.7e-83	273.8	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2904408851	173	87.1	2	172	17	178	2.2e-39	129.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2904408852	111	59.48	28	110	18	86	9.9e-04	13.5	COG1460	DNA-directed RNA polymerase, subunit F	114
2904408853	135	60.37	8	129	45	143	6.9e-11	36.8	COG2010	Cytochrome c, mono- and diheme variants	150
2904408856	818	99.12	89	818	8	795	1.1e-121	402.3	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904408857	232	70.9	1	232	92	320	6.8e-75	246.3	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2904408858	96	21.67	1	95	7	76	3.7e-11	36.9	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2904408859	185	91.4	11	185	9	178	3.6e-40	131.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2904408860	410	28.67	244	408	270	396	2.3e-57	59.2	COG3182	Uncharacterized iron-regulated membrane protein	442
2904408860	410	46.5	12	242	5	210	2.3e-57	132.1	COG3182	Uncharacterized iron-regulated membrane protein	442
2904408862	337	97.52	1	337	7	321	3.4e-87	286.7	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2904408863	174	87.1	4	174	19	180	8.5e-39	127.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2904408864	114	14.9	29	110	148	213	5.8e-11	35.5	COG3182	Uncharacterized iron-regulated membrane protein	442
2904408866	331	43.37	3	331	423	749	7.0e-19	61.5	COG4772	Outer membrane receptor for Fe3+-dicitrate	753
2904408867	579	93.87	3	485	3	477	4.7e-70	230.9	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
2904408868	497	94.66	4	497	3	481	9.2e-110	361.8	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
2904408869	498	94.86	7	497	3	482	7.4e-101	332.3	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
2904408870	105	87.72	5	104	5	104	9.8e-15	45.5	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
2904408871	245	45.45	4	85	84	158	9.8e-19	24.4	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
2904408871	245	73.33	90	221	24	144	9.8e-19	42.7	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
2904408872	90	83.91	1	81	8	80	4.7e-15	50	COG1563	Uncharacterized MnhB-related membrane protein	87
2904408873	107	83.19	4	106	4	97	1.7e-21	70.5	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
2904408874	91	80.9	3	88	11	82	3.3e-14	47.2	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
2904408875	166	82.91	7	153	8	138	1.8e-19	64.5	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
2904408876	68	67.12	1	65	2	50	5.8e-14	46.1	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
2904408879	778	17.22	139	257	209	265	3.9e-29	37.3	COG0790	TPR repeat	292
2904408879	778	70.69	62	205	71	304	3.9e-29	73.5	COG0790	TPR repeat	292
2904408883	247	99.21	1	246	1	251	2.8e-51	168.8	COG1521	Pantothenate kinase type III	251
2904408884	329	87.34	3	79	9	77	1.1e-22	73.3	COG1654	Biotin operon repressor	79
2904408884	329	99.16	90	328	2	238	1.8e-63	208.6	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
2904408886	437	96.57	1	434	12	433	0.0e+00	589.9	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
2904408887	207	96.24	1	205	5	209	8.3e-43	140.6	COG2834	Outer membrane lipoprotein-sorting protein	211
2904408888	453	98.86	10	453	1	434	0.0e+00	432	COG0015	Adenylosuccinate lyase	438
2904408889	374	98.88	1	360	3	355	0.0e+00	491.5	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
2904408890	159	68.02	2	148	7	123	3.9e-13	44	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2904408892	106	92.52	1	106	8	106	1.1e-43	142	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
2904408893	755	40.75	416	748	475	802	0.0e+00	447.3	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2904408893	755	49.81	1	424	2	402	0.0e+00	521.1	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2904408894	72	96	1	72	1	72	1.1e-38	124.9	COG0361	Translation initiation factor IF-1	75
2904408895	241	94.47	1	239	9	247	8.5e-80	262.1	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
2904408896	234	96.83	12	231	2	215	1.5e-85	279.6	COG2360	Leu/Phe-tRNA-protein transferase	221
2904408897	396	97.93	5	388	7	385	0.0e+00	470.6	COG3146	Predicted N-acyltransferase	387
2904408898	555	99.44	3	537	3	534	0.0e+00	596.5	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2904408899	215	98.14	2	209	2	212	1.1e-39	130.8	COG0625	Glutathione S-transferase	211
2904408900	580	94.23	1	505	27	516	0.0e+00	519.6	COG0513	Superfamily II DNA and RNA helicase	513
2904408901	295	97.23	1	290	6	286	1.3e-113	373.1	COG2607	Predicted ATPase, AAA+ superfamily	287
2904408902	372	97.41	8	372	2	377	1.8e-39	129.3	COG2327	Polysaccharide pyruvyl transferase family protein WcaK	385
2904408904	84	47.89	1	77	11	78	1.0e-06	23.3	COG0727	Fe-S-cluster containining protein	132
2904408905	115	75.18	1	108	31	136	1.5e-23	77.5	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2904408906	368	91.05	7	355	19	313	1.3e-14	45.6	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2904408907	344	99.43	1	343	1	347	0.0e+00	457.4	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
2904408909	192	99.1	2	112	1	110	8.4e-28	91	COG4226	Predicted nuclease of the RNAse H fold, HicB family	111
2904408914	187	83.14	37	179	13	155	2.5e-15	50.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2904408915	331	92.35	1	327	26	351	0.0e+00	433.1	COG0407	Uroporphyrinogen-III decarboxylase	352
2904408916	540	59.93	289	522	121	301	5.7e-13	43	COG3266	Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain	292
2904408917	360	98.89	1	359	1	356	0.0e+00	451.7	COG0337	3-dehydroquinate synthetase	360
2904408918	186	97.09	13	185	3	169	2.8e-60	197.5	COG0703	Shikimate kinase	172
2904408919	701	93.29	18	696	48	714	0.0e+00	499.8	COG4796	Type II secretory pathway, component HofQ	709
2904408920	155	85.88	1	152	23	168	1.3e-46	152.9	COG3168	Tfp pilus assembly protein PilP	170
2904408921	214	92.42	1	213	10	204	6.2e-63	206.5	COG3167	Tfp pilus assembly protein PilO	211
2904408922	194	87.98	1	194	4	186	2.2e-44	145.8	COG3166	Tfp pilus assembly protein PilN	206
2904408923	353	97.46	2	353	9	353	8.4e-123	404.1	COG4972	Tfp pilus assembly protein, ATPase PilM	354
2904408924	805	95.72	1	795	6	766	0.0e+00	967.9	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
2904408927	237	90.73	1	233	24	258	7.1e-79	259	COG0708	Exonuclease III	261
2904408928	443	49.09	218	434	8	195	4.2e-08	2.9	COG0477	MFS family permease	338
2904408928	443	64.75	9	252	2	249	4.2e-08	27	COG0477	MFS family permease	338
2904408929	473	98.9	5	459	4	453	0.0e+00	557.6	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2904408930	447	99.31	3	447	3	433	0.0e+00	460.2	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2904408931	895	99.21	12	895	6	885	0.0e+00	1435.3	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
2904408933	422	98.03	13	421	6	404	0.0e+00	440.8	COG0303	Molybdopterin biosynthesis enzyme	404
2904408934	363	94.61	47	348	8	288	8.6e-89	291.7	COG1533	DNA repair photolyase	297
2904408935	380	91.26	153	361	14	180	3.9e-54	177.1	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904408936	333	73.85	5	289	73	312	2.3e-45	149.6	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2904408937	96	92.22	1	93	5	87	1.4e-29	96.6	COG0271	Stress-induced morphogen (activity unknown)	90
2904408938	99	97.83	1	98	2	91	3.8e-32	104.9	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
2904408939	180	97.22	1	180	1	175	1.1e-69	228.7	COG2917	Intracellular septation protein A	180
2904408941	103	93.27	1	100	6	102	3.8e-47	153.2	COG3492	Uncharacterized protein	104
2904408942	114	57.97	57	114	17	56	3.5e-09	9.3	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2904408942	114	65.22	1	62	1	45	3.5e-09	20.1	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2904408943	129	62.26	23	129	61	159	2.0e-18	60.7	COG1580	Flagellar basal body-associated protein FliL	159
2904408944	348	70.98	4	338	7	302	5.5e-89	293.3	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2904408945	184	94.97	6	182	7	176	1.8e-48	158.4	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
2904408946	245	92.4	1	245	19	261	3.3e-76	250.7	COG0005	Purine nucleoside phosphorylase	262
2904408947	148	84.46	6	148	23	147	3.0e-26	86.7	COG5501	Predicted secreted protein	148
2904408949	526	99.24	1	526	4	527	0.0e+00	854.4	COG4108	Peptide chain release factor RF-3	528
2904408955	318	97.06	1	139	1	132	9.4e-17	55.2	COG1943	REP element-mobilizing transposase RayT	136
2904408956	125	84.38	63	123	3	56	2.2e-23	76.1	COG3411	(2Fe-2S) ferredoxin	64
2904408958	118	97.17	11	116	2	104	5.2e-37	120.9	COG2076	Multidrug transporter EmrE and related cation transporters	106
2904408959	100	39.59	5	100	120	197	2.1e-26	87.6	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2904408960	280	84.3	2	260	2	334	2.1e-30	99.7	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2904408961	310	98.01	1	303	5	300	3.5e-60	197.8	COG1597	Diacylglycerol kinase family enzyme	301
2904408962	505	98.7	8	294	1	304	3.0e-88	289.9	COG3854	Stage III sporulation protein SpoIIIAA	308
2904408963	496	97.38	1	496	5	487	0.0e+00	706.7	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
2904408964	420	99.06	1	420	1	420	0.0e+00	546.9	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
2904408965	640	99.85	1	640	1	649	0.0e+00	972.5	COG2766	Predicted Ser/Thr protein kinase	649
2904408966	443	88.04	31	426	9	398	6.7e-47	155	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2904408967	287	95.64	1	281	6	290	1.8e-81	268	COG1175	ABC-type sugar transport system, permease component	295
2904408968	271	93.99	2	270	18	283	8.4e-79	259.1	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2904408969	382	99.71	1	373	1	349	0.0e+00	455	COG3839	ABC-type sugar transport system, ATPase component	338
2904408970	595	95.35	2	592	22	616	4.9e-91	298.2	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
2904408972	367	45.9	110	366	10	177	1.9e-07	24.7	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2904408973	126	52.61	2	124	2	112	1.6e-20	67.9	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2904408974	218	99.05	5	217	2	210	1.9e-64	211.4	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2904408975	1273	9.11	827	919	30	107	3.3e-70	24.8	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904408975	1273	25.58	688	885	332	550	3.3e-70	16.3	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904408975	1273	30.49	570	833	16	276	3.3e-70	48.4	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904408975	1273	38.32	889	1221	403	730	3.3e-70	105	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904408975	1273	40.65	198	589	200	547	3.3e-70	76.2	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904408979	405	60	72	404	147	371	1.5e-59	196.5	COG4585	Signal transduction histidine kinase	365
2904408980	177	21.66	22	175	7	40	2.7e-04	15.1	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2904408981	316	13.5	228	282	230	266	6.8e-05	5.5	COG1240	Mg-chelatase subunit ChlD	261
2904408981	316	47.81	21	178	84	214	6.8e-05	8.2	COG1240	Mg-chelatase subunit ChlD	261
2904408982	188	39.95	4	176	176	322	8.4e-06	20.6	COG0457	Tetratricopeptide (TPR) repeat	291
2904408985	285	50.84	12	270	173	384	1.0e-10	35.3	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2904408986	339	94.24	7	339	17	327	1.0e-53	176.8	COG0714	MoxR-like ATPase	329
2904408988	157	56.1	18	155	49	140	5.3e-09	30.8	COG2010	Cytochrome c, mono- and diheme variants	150
2904408989	289	75.62	1	257	43	256	5.8e-09	29.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904408990	601	79.43	4	601	137	750	2.2e-119	393.1	COG4993	Glucose dehydrogenase	773
2904408991	477	77.87	145	472	83	374	1.6e-53	175.7	COG4585	Signal transduction histidine kinase	365
2904408992	215	99.53	5	214	1	210	2.0e-58	191.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2904408993	755	90.06	2	751	53	768	8.6e-46	151.1	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2904408994	195	21.46	2	100	57	100	2.0e-05	4.2	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
2904408994	195	27.8	103	184	126	182	2.0e-05	12.6	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
2904408995	304	69.19	1	296	4	259	1.1e-33	110.9	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2904408996	255	94.3	1	254	6	253	3.9e-94	309	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
2904408997	378	90.64	110	378	24	265	1.3e-72	238.3	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2904408998	274	78	1	270	7	325	8.1e-27	85.8	COG0672	High-affinity Fe2+/Pb2+ permease	383
2904408999	95	63.28	4	95	46	126	7.0e-07	23.6	COG3794	Plastocyanin	128
2904409000	498	98.6	1	498	6	499	0.0e+00	724.4	COG0554	Glycerol kinase	499
2904409001	119	13.64	4	34	4	24	2.4e-03	3.6	COG3133	Outer membrane lipoprotein SlyB	154
2904409001	119	32.47	28	90	58	107	2.4e-03	11.2	COG3133	Outer membrane lipoprotein SlyB	154
2904409004	212	75.12	1	207	6	162	5.6e-25	83.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904409005	354	88.21	1	347	37	380	1.4e-61	203	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904409006	1065	99.8	3	1041	2	1013	0.0e+00	1136.8	COG0841	Multidrug efflux pump subunit AcrB	1009
2904409007	504	98.7	33	497	1	454	1.9e-114	377.3	COG1538	Outer membrane protein TolC	457
2904409008	170	83.33	1	168	9	163	3.3e-21	70	COG1443	Isopentenyldiphosphate isomerase	185
2904409009	191	88.36	53	189	10	138	1.5e-15	51.3	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2904409010	382	85.71	30	381	55	408	4.6e-94	309.8	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2904409011	480	99.78	2	480	1	464	0.0e+00	628.8	COG0215	Cysteinyl-tRNA synthetase	464
2904409012	466	97.5	1	464	10	477	4.0e-116	383.2	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2904409013	489	97.39	1	489	4	488	0.0e+00	515.1	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
2904409014	1107	7.61	16	121	18	84	0.0e+00	7.2	COG3002	Uncharacterized conserved protein YbcC, UPF0753/DUF2309 family	880
2904409014	1107	17.73	174	411	133	288	0.0e+00	92	COG3002	Uncharacterized conserved protein YbcC, UPF0753/DUF2309 family	880
2904409014	1107	58.98	506	1066	347	865	0.0e+00	456.3	COG3002	Uncharacterized conserved protein YbcC, UPF0753/DUF2309 family	880
2904409015	518	56.73	6	383	2	351	1.8e-90	296.3	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2904409016	509	98.19	11	509	3	491	4.3e-91	300.3	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
2904409017	518	98.19	3	504	2	490	0.0e+00	456.8	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
2904409018	181	25.93	1	180	14	159	1.6e-32	107	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2904409021	93	37.7	3	86	64	132	1.8e-10	33.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904409025	920	55.98	273	455	112	256	2.2e-07	24.1	COG0708	Exonuclease III	261
2904409027	332	74.83	42	325	32	248	3.2e-18	59.6	COG0382	4-hydroxybenzoate polyprenyltransferase	289
2904409028	124	99.32	4	121	2	146	6.1e-15	50.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2904409029	310	98.66	8	305	3	296	0.0e+00	543.7	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
2904409030	691	99.57	2	691	3	690	0.0e+00	829	COG0751	Glycyl-tRNA synthetase, beta subunit	691
2904409031	180	85.79	1	179	6	162	4.3e-53	173.7	COG0241	Histidinol phosphatase or a related phosphatase	181
2904409032	250	79.31	11	229	7	213	2.2e-46	152.3	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2904409033	392	9.36	1	73	7	66	8.6e-21	3.8	COG1449	Alpha-amylase/alpha-mannosidase, GH57 family	615
2904409033	392	45.4	79	376	200	490	8.6e-21	65.2	COG1449	Alpha-amylase/alpha-mannosidase, GH57 family	615
2904409036	269	96.97	1	262	1	256	2.0e-39	130.2	COG1192	Cellulose biosynthesis protein BcsQ	259
2904409042	179	80.44	1	172	40	220	3.5e-52	167	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2904409043	54	7.05	1	50	572	615	8.6e-10	32.4	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
2904409044	397	60	49	396	147	371	1.9e-60	199.4	COG4585	Signal transduction histidine kinase	365
2904409045	219	99.05	5	218	2	210	2.2e-63	207.9	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2904409046	128	59.24	2	128	2	126	1.1e-23	78.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2904409048	407	51.24	10	405	44	291	1.7e-24	81.1	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904409049	437	53.72	11	371	42	301	4.2e-21	69.6	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904409050	627	17.15	372	512	123	205	2.9e-18	2.9	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904409050	627	53.93	45	374	67	327	2.9e-18	60.1	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904409052	743	75.84	26	451	46	475	1.0e-28	95.3	COG1404	Serine protease, subtilisin family	508
2904409053	203	62.38	7	183	26	156	4.1e-30	99.1	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
2904409054	554	9.15	60	102	72	86	6.5e-04	5.3	COG2010	Cytochrome c, mono- and diheme variants	150
2904409054	554	41.46	103	177	86	153	6.5e-04	6.5	COG2010	Cytochrome c, mono- and diheme variants	150
2904409059	60	21.23	12	59	139	183	2.4e-11	38	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
2904409062	399	18.5	196	271	247	310	9.7e-25	10.9	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
2904409062	399	22.54	58	155	48	125	9.7e-25	22	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
2904409062	399	25.43	143	254	40	127	9.7e-25	23.1	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
2904409062	399	32.95	257	393	17	130	9.7e-25	33.2	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
2904409063	638	12.55	104	210	138	206	0.0e+00	8.8	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2904409063	638	63.82	288	638	197	547	0.0e+00	480	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2904409064	88	29.29	8	82	38	66	5.7e-04	13.6	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
2904409065	147	76.8	6	131	2	97	8.1e-19	62.5	COG3293	Transposase	124
2904409073	114	51.54	10	111	7	73	5.0e-06	21.9	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2904409074	175	60.71	1	164	9	110	8.7e-08	26.6	COG5654	Uncharacterized conserved protein, contains RES domain	163
2904409088	308	81.79	7	307	49	322	1.2e-26	88.3	COG0582	Integrase	309
2904409090	211	65.91	1	194	1	174	1.0e-33	111.6	COG1192	Cellulose biosynthesis protein BcsQ	259
2904409091	282	66.67	5	260	48	233	3.6e-18	60.6	COG0500	SAM-dependent methyltransferase	257
2904409093	139	26.44	3	139	215	292	4.7e-08	27.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904409094	486	97.81	20	486	7	452	4.7e-127	418.8	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2904409095	151	63.36	6	117	34	116	1.5e-08	28.6	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2904409096	300	98.31	13	292	5	294	2.8e-32	106.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904409099	424	30	1	142	4	126	2.2e-33	76.7	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2904409099	424	43.17	166	408	216	392	2.2e-33	31.7	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2904409100	43	72.97	1	37	1	27	2.4e-18	60.2	COG4890	Predicted outer membrane lipoprotein	37
2904409101	378	98.55	1	372	1	340	2.3e-107	353.5	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
2904409102	523	98.68	4	521	3	452	0.0e+00	615.6	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
2904409104	243	78.8	2	243	55	277	2.5e-61	201.3	COG5486	Predicted metal-binding membrane protein	283
2904409105	202	98.08	1	202	1	204	2.0e-52	172.4	COG5588	Uncharacterized protein	207
2904409106	530	69.89	203	516	101	404	7.6e-101	330.9	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain	403
2904409107	216	40.21	29	201	75	189	1.1e-04	15.5	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2904409108	243	75	1	233	4	204	4.1e-33	109.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904409110	280	96.41	17	280	8	249	1.7e-70	231.8	COG4798	Predicted methyltransferase	238
2904409113	150	97.33	1	150	2	147	1.2e-57	188.4	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
2904409115	504	74.77	419	504	11	90	4.3e-13	42.3	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2904409115	504	95.62	26	397	4	374	2.6e-48	159.3	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2904409116	58	16.05	1	55	63	110	1.9e-03	12	COG1230	Co/Zn/Cd efflux system component	296
2904409117	142	27.85	4	140	28	115	2.6e-07	24.2	COG4743	Uncharacterized membrane protein	316
2904409119	1233	98.08	5	330	6	311	1.4e-128	422.2	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
2904409119	1233	99.88	331	1198	2	857	0.0e+00	1351	COG1410	Methionine synthase I, cobalamin-binding domain	842
2904409120	607	92.33	17	607	48	613	1.5e-60	199.6	COG4206	Outer membrane cobalamin receptor protein	608
2904409121	1013	54.62	794	1004	65	265	5.9e-12	18.8	COG0457	Tetratricopeptide (TPR) repeat	291
2904409121	1013	73.1	518	824	63	331	5.9e-12	26.3	COG0457	Tetratricopeptide (TPR) repeat	291
2904409121	1013	79.05	1	131	5	121	1.4e-29	95.9	COG3710	DNA-binding winged helix-turn-helix (wHTH) domain	148
2904409123	462	99.35	4	459	2	460	0.0e+00	651.8	COG0114	Fumarate hydratase class II	462
2904409124	540	95.71	1	309	8	319	2.0e-67	222.1	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2904409126	184	58.01	5	183	60	193	2.3e-16	54.4	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
2904409127	422	98.53	4	409	2	404	1.6e-17	58.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904409128	109	56.32	1	109	72	178	1.1e-30	101.2	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2904409129	268	64.55	1	259	143	406	5.9e-35	116.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904409131	362	56.72	13	342	172	403	2.7e-30	100.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904409132	400	78.42	1	397	29	406	2.8e-38	125.9	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2904409135	313	98.75	1	310	3	319	5.8e-81	266.8	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2904409136	362	99.42	1	347	2	343	0.0e+00	587	COG1089	GDP-D-mannose dehydratase	345
2904409137	719	27.41	212	304	27	63	1.8e-05	7.3	COG2863	Cytochrome c553	121
2904409137	719	37.78	405	484	8	58	1.8e-05	6.7	COG2863	Cytochrome c553	121
2904409144	315	86.69	3	306	31	323	1.9e-67	221.6	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
2904409150	163	82	3	153	24	146	9.3e-15	49.2	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2904409152	751	6.58	395	439	221	244	7.1e-30	3.4	COG1858	Cytochrome c peroxidase	364
2904409152	751	8.77	21	133	57	88	7.1e-30	16.5	COG1858	Cytochrome c peroxidase	364
2904409152	751	11.23	596	697	290	330	7.1e-30	42.1	COG1858	Cytochrome c peroxidase	364
2904409152	751	16.99	178	295	99	160	7.1e-30	31.4	COG1858	Cytochrome c peroxidase	364
2904409154	509	15.6	1	61	39	77	3.0e-07	9.6	COG3063	Tfp pilus assembly protein PilF	250
2904409154	509	19.2	141	210	40	87	3.0e-07	2.7	COG3063	Tfp pilus assembly protein PilF	250
2904409154	509	28.8	56	146	32	103	3.0e-07	13.6	COG3063	Tfp pilus assembly protein PilF	250
2904409155	62	12.4	3	60	39	69	2.8e-07	24.4	COG3063	Tfp pilus assembly protein PilF	250
2904409157	149	99.39	3	122	1	162	1.8e-33	110.2	COG0517	CBS domain	117
2904409159	103	27.66	2	98	121	211	2.6e-22	74	COG0724	 RNA recognition motif (RRM) domain	306
2904409161	417	73.85	1	410	29	412	0.0e+00	502.4	COG0513	Superfamily II DNA and RNA helicase	513
2904409162	474	65.22	5	442	217	623	0.0e+00	453.6	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2904409163	1025	8.13	858	966	526	583	1.4e-68	13.5	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2904409163	1025	89.76	51	866	2	641	1.4e-68	210.7	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2904409164	541	79.38	30	529	49	433	4.1e-46	151.7	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2904409166	406	97.28	43	340	6	255	8.7e-24	76.5	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2904409168	266	85.48	6	226	4	215	3.6e-19	62.5	COG2129	Predicted phosphoesterase, related to the Icc protein	226
2904409169	936	59.5	79	392	99	242	1.7e-32	59	COG2202	PAS domain	232
2904409169	936	66.5	613	925	130	391	3.1e-69	228.8	COG0642	Signal transduction histidine kinase	336
2904409169	936	73.14	348	516	66	242	1.7e-32	54.8	COG2202	PAS domain	232
2904409171	256	78.23	1	239	64	293	7.1e-73	239.6	COG4302	Ethanolamine ammonia-lyase, small subunit	294
2904409172	465	97.13	1	449	1	440	0.0e+00	708.2	COG4303	Ethanolamine ammonia-lyase, large subunit	453
2904409173	492	98.75	18	492	2	474	0.0e+00	636.7	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2904409179	213	89.62	10	213	3	192	4.4e-35	115.5	COG3531	Predicted protein-disulfide isomerase , contains CxxC motif	212
2904409181	321	99.7	1	313	1	330	5.0e-83	273.4	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2904409183	756	84.52	505	756	17	218	3.0e-17	57.1	COG5571	Uncharacterized protein YhjY, contains autotransporter beta-barrel domain	239
2904409184	983	43.14	382	667	6	291	4.0e-124	242.3	COG0021	Transketolase	663
2904409184	983	46.76	671	983	351	660	4.0e-124	165.4	COG0021	Transketolase	663
2904409184	983	98.68	9	371	3	302	6.8e-66	216.8	COG0176	Transaldolase	239
2904409185	395	85.35	6	384	2	368	1.4e-50	167.1	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2904409186	141	90.91	3	139	12	141	2.8e-32	106	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2904409187	512	39.3	93	252	27	105	5.3e-05	15.8	COG2112	Predicted Ser/Thr protein kinase	201
2904409188	184	56.71	27	169	59	151	9.0e-16	52.4	COG2010	Cytochrome c, mono- and diheme variants	150
2904409189	347	89.76	18	265	5	232	2.1e-61	201.4	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2904409191	648	93.15	32	581	8	537	0.0e+00	679.2	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2904409192	202	84.04	9	200	32	210	3.9e-40	131.6	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2904409194	318	86.33	31	312	11	269	2.3e-45	149.1	COG3336	Cytochrome c oxidase assembly factor CtaG	299
2904409195	621	85.51	6	621	112	772	2.2e-113	373.1	COG4993	Glucose dehydrogenase	773
2904409196	141	34.56	32	141	21	67	9.1e-07	16.6	COG3474	Cytochrome c2	135
2904409198	154	62.83	6	154	6	147	1.2e-34	114.3	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
2904409203	497	14.37	193	228	33	56	3.4e-07	4.4	COG2131	Deoxycytidylate deaminase	164
2904409203	497	14.97	121	163	31	55	3.4e-07	4.8	COG2131	Deoxycytidylate deaminase	164
2904409203	497	15.57	305	346	27	52	3.4e-07	7.1	COG2131	Deoxycytidylate deaminase	164
2904409206	461	84.21	254	360	15	110	2.4e-34	21.5	COG0607	Rhodanese-related sulfurtransferase	110
2904409206	461	89.62	4	216	25	257	3.2e-37	122.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2904409206	461	91.23	358	461	8	111	2.4e-34	88.7	COG0607	Rhodanese-related sulfurtransferase	110
2904409208	898	67.43	696	896	51	226	3.9e-29	95.2	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2904409208	898	69.14	580	645	17	72	2.4e-06	21.1	COG0236	Acyl carrier protein	80
2904409208	898	82.06	3	556	22	524	3.5e-118	389	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2904409209	354	8.51	290	344	310	341	3.4e-42	5.4	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2904409209	354	48.94	5	255	14	197	3.4e-42	133.9	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2904409210	374	67.04	45	374	103	405	6.0e-36	118.1	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
2904409211	558	11.68	126	361	305	373	6.5e-18	17.5	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
2904409211	558	27.75	381	558	428	591	6.5e-18	46.4	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
2904409212	667	43.9	384	505	9	80	4.6e-07	18.5	COG2010	Cytochrome c, mono- and diheme variants	150
2904409213	323	24.57	223	322	81	179	1.2e-63	62.4	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904409213	323	29.03	14	153	137	253	1.2e-63	69.9	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904409213	323	49.38	100	283	80	278	1.2e-63	104.7	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904409215	1046	99.32	1	1039	1	1023	0.0e+00	1276	COG3696	Cu/Ag efflux pump CusA	1027
2904409216	124	88.37	1	122	10	123	1.9e-36	119.1	COG2852	Very-short-patch-repair endonuclease	129
2904409217	335	86.92	2	327	35	373	4.9e-33	102.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904409218	412	84.57	12	410	39	427	1.0e-36	120.1	COG1538	Outer membrane protein TolC	457
2904409219	191	79.03	17	176	39	185	2.0e-30	100.5	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2904409221	1070	99.22	1	1038	1	1022	0.0e+00	1351.6	COG3696	Cu/Ag efflux pump CusA	1027
2904409222	479	87.18	118	463	34	373	1.8e-38	120.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904409223	436	88.26	28	435	42	447	4.7e-51	168.2	COG1538	Outer membrane protein TolC	457
2904409225	683	89.47	1	682	76	729	0.0e+00	783.7	COG2217	Cation transport ATPase	713
2904409228	325	96.27	4	251	5	262	1.0e-54	180	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904409229	988	93.48	1	900	47	949	0.0e+00	841.5	COG0474	Magnesium-transporting ATPase (P-type)	917
2904409231	98	20.25	16	91	100	132	4.2e-04	13.1	COG5126	Ca2+-binding protein, EF-hand superfamily	160
2904409232	147	18.34	1	39	6	36	2.0e-08	10.6	COG4639	Predicted kinase	168
2904409232	147	39.64	36	131	66	132	2.0e-08	16.2	COG4639	Predicted kinase	168
2904409235	375	95.36	3	375	3	372	1.4e-60	199.9	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2904409236	156	75.17	28	155	32	140	6.6e-04	12.9	COG3212	Uncharacterized membrane protein YkoI	144
2904409237	396	97.2	11	395	8	389	1.9e-121	400	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2904409238	363	97.83	1	363	6	366	5.1e-88	289.9	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
2904409240	623	24.94	305	615	286	390	2.1e-24	70	COG2124	Cytochrome P450	411
2904409240	623	33.49	89	272	23	163	2.1e-24	12.8	COG2124	Cytochrome P450	411
2904409242	335	98.13	1	334	3	317	4.9e-50	164.9	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2904409243	340	13.48	221	291	302	358	1.0e-47	14.4	COG3673	Uncharacterized protein, PA2063/DUF2235 family	423
2904409243	340	57.92	1	244	30	274	1.0e-47	148.1	COG3673	Uncharacterized protein, PA2063/DUF2235 family	423
2904409246	421	98.04	24	421	1	400	2.7e-72	238.5	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
2904409247	223	63.68	89	223	60	180	1.2e-20	68.2	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2904409248	931	54.08	708	928	146	344	5.3e-55	50.6	COG0457	Tetratricopeptide (TPR) repeat	291
2904409248	931	64.4	11	233	104	340	5.3e-55	35.4	COG0457	Tetratricopeptide (TPR) repeat	291
2904409248	931	68.75	572	782	54	306	5.3e-55	36.4	COG0457	Tetratricopeptide (TPR) repeat	291
2904409248	931	76.36	212	453	65	345	5.3e-55	57.4	COG0457	Tetratricopeptide (TPR) repeat	291
2904409248	931	77.72	402	675	58	343	5.3e-55	57.5	COG0457	Tetratricopeptide (TPR) repeat	291
2904409250	227	96.82	13	227	7	219	2.6e-51	168.2	COG4122	Predicted O-methyltransferase YrrM	219
2904409251	546	99.56	39	536	3	453	0.0e+00	638.9	COG0166	Glucose-6-phosphate isomerase	446
2904409252	135	89.58	2	135	3	131	3.1e-32	105.8	COG2703	Hemerythrin	144
2904409253	465	99.35	3	461	3	458	0.0e+00	686.7	COG0165	Argininosuccinate lyase	459
2904409254	208	89.95	7	204	5	192	1.9e-44	146.1	COG0406	Broad specificity phosphatase PhoE	208
2904409255	116	84	2	116	13	117	3.2e-29	95.8	COG3671	Uncharacterized membrane protein	125
2904409256	233	63.23	1	230	2	240	2.8e-55	181.8	COG1208	NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins	358
2904409257	338	95.44	1	335	10	344	4.9e-99	325.7	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
2904409258	921	91.58	173	920	47	775	0.0e+00	450.3	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
2904409259	449	47.08	287	440	167	319	5.6e-83	132.7	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2904409259	449	81.85	12	292	6	271	5.6e-83	143.7	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2904409260	326	96.98	1	319	8	328	1.8e-120	396.5	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
2904409261	260	98.08	2	259	3	257	2.1e-87	286.8	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
2904409262	524	95.04	1	510	23	520	0.0e+00	565.2	COG0033	Phosphoglucomutase	524
2904409263	184	48	8	184	41	184	3.6e-13	42.4	COG3034	Murein L,D-transpeptidase YafK	298
2904409264	92	84.81	1	77	9	75	5.0e-07	23.9	COG4238	Outer membrane murein-binding lipoprotein Lpp	78
2904409265	248	85.11	1	244	36	275	1.6e-67	222.1	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
2904409266	222	98.19	3	222	4	220	1.4e-78	257.6	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
2904409267	209	93.3	6	208	2	196	1.2e-70	231.6	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
2904409269	539	29.41	141	186	36	50	6.7e+00	11.9	COG1998	Ribosomal protein S27AE	51
2904409270	439	97.73	4	436	9	439	0.0e+00	485.1	COG1362	Aspartyl aminopeptidase	437
2904409272	1127	58.26	414	548	102	242	2.2e-42	61.3	COG2202	PAS domain	232
2904409272	1127	58.68	548	698	100	241	2.2e-42	29	COG2202	PAS domain	232
2904409272	1127	59.5	71	423	99	242	2.2e-42	63.8	COG2202	PAS domain	232
2904409272	1127	93.39	879	1127	3	242	3.2e-71	232.9	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2904409272	1127	96.72	686	866	7	183	2.7e-53	172.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904409273	142	77.33	2	140	21	153	7.5e-26	84.7	COG0622	Predicted phosphodiesterase	172
2904409275	166	74.87	5	165	18	157	1.3e-11	39	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2904409276	124	81.82	2	122	4	111	2.1e-27	89.7	COG1833	Uri superfamily endonuclease	132
2904409277	244	95.67	1	244	11	253	6.0e-56	183.8	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
2904409278	518	93.08	2	518	33	530	0.0e+00	676	COG3131	Periplasmic glucans biosynthesis protein	534
2904409279	710	71.83	69	706	109	391	4.2e-63	206	COG0642	Signal transduction histidine kinase	336
2904409280	128	92.48	1	124	5	127	1.6e-37	122.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2904409281	446	99.14	1	444	3	465	0.0e+00	535	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904409282	466	52.07	11	157	117	242	2.7e-25	36.6	COG2202	PAS domain	232
2904409282	466	77.69	104	281	55	242	2.7e-25	52.9	COG2202	PAS domain	232
2904409282	466	95.08	269	449	8	181	3.2e-57	187.2	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904409283	290	78.2	1	253	13	238	8.0e-47	153.6	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
2904409284	268	96.3	8	268	5	264	2.8e-52	171.9	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
2904409285	433	94.34	1	430	8	407	1.1e-105	347.8	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2904409286	1046	94.51	116	1044	45	957	0.0e+00	715.7	COG0474	Magnesium-transporting ATPase (P-type)	917
2904409287	395	98.46	1	395	1	383	6.3e-125	411.3	COG0192	S-adenosylmethionine synthetase	388
2904409288	369	91.01	1	148	14	185	2.2e-26	86.4	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2904409289	491	96.83	170	484	10	314	3.0e-68	224	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2904409292	63	7.46	1	56	483	524	2.2e-04	14.1	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2904409294	117	37.06	29	113	123	195	7.8e-27	88.9	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2904409295	796	96.25	26	779	11	754	0.0e+00	694.8	COG1554	Trehalose and maltose hydrolase (possible phosphorylase)	772
2904409296	298	50.94	4	130	78	158	8.5e-16	18.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2904409296	298	95.6	136	281	5	156	8.5e-16	31.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2904409297	253	95.93	14	253	2	213	2.5e-46	150.4	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2904409298	1058	96.07	2	906	22	949	0.0e+00	863.5	COG0474	Magnesium-transporting ATPase (P-type)	917
2904409300	137	86.18	1	128	20	150	1.3e-26	87.4	COG0782	Transcription elongation factor, GreA/GreB family	151
2904409302	378	99.45	6	369	2	360	1.9e-81	268.2	COG3177	Fic family protein	348
2904409307	896	99.18	7	769	5	733	1.2e-106	351.5	COG1033	Predicted exporter protein, RND superfamily	727
2904409308	3064	6.91	2936	3058	842	923	0.0e+00	14.2	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2904409308	3064	45.49	2212	2792	4	543	0.0e+00	682	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2904409308	3064	66.42	1827	2127	5	182	6.7e-17	54.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904409308	3064	84.84	688	1755	5	1011	0.0e+00	1052.1	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2904409308	3064	85.19	601	675	6	74	3.3e-07	18.6	COG0236	Acyl carrier protein	80
2904409308	3064	96.3	31	584	14	560	8.7e-83	272.2	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2904409309	2176	65.9	590	1344	221	647	1.3e-99	329.1	COG1020	Non-ribosomal peptide synthetase component F	642
2904409309	2176	98.51	1913	2147	4	267	8.6e-69	226.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904409310	420	43.08	215	417	13	177	5.8e-25	26.2	COG0477	MFS family permease	338
2904409310	420	73.63	12	245	8	289	5.8e-25	59.8	COG0477	MFS family permease	338
2904409311	230	69.74	19	222	39	197	1.6e-34	113.7	COG2977	4'-phosphopantetheinyl transferase EntD (siderophore biosynthesis)	228
2904409312	385	11.57	93	131	132	156	1.2e-04	5.7	COG0778	Nitroreductase	207
2904409312	385	17.13	209	378	127	163	1.2e-04	2	COG0778	Nitroreductase	207
2904409312	385	18.52	41	102	27	66	1.2e-04	8.8	COG0778	Nitroreductase	207
2904409313	200	95.27	55	198	5	145	2.3e-30	99.3	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2904409314	415	83.76	64	407	13	239	9.5e-25	81.6	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2904409318	845	79.01	20	784	157	792	0.0e+00	645.3	COG2374	Predicted extracellular nuclease	798
2904409319	868	69.84	36	772	146	541	3.8e-14	43	COG1404	Serine protease, subtilisin family	508
2904409322	427	90.05	2	409	42	412	6.5e-94	306.1	COG4222	Uncharacterized conserved protein	391
2904409323	171	44.18	3	153	171	318	4.3e-16	53.6	COG0582	Integrase	309
2904409327	53	4.88	3	46	416	454	5.4e-09	28.1	COG3451	Type IV secretory pathway, VirB4 component	796
2904409328	65	37.59	2	65	26	78	1.3e-03	13.5	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
2904409329	331	91.67	6	326	15	300	5.7e-82	269.2	COG0630	Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase	312
2904409330	393	87.79	10	391	43	387	1.9e-80	265.4	COG2948	Type IV secretory pathway, VirB10 components	360
2904409331	249	78.75	7	245	39	253	2.5e-51	168.7	COG3504	Type IV secretory pathway, VirB9 components	265
2904409332	228	91.21	1	224	19	236	8.8e-43	140.4	COG3736	Type IV secretory pathway, component VirB8	239
2904409333	337	14.62	232	319	345	407	4.2e-16	1.1	COG3704	Type IV secretory pathway, VirB6 components	406
2904409333	337	23.67	74	236	195	296	4.2e-16	53.2	COG3704	Type IV secretory pathway, VirB6 components	406
2904409335	263	19.75	45	89	69	99	5.3e-04	5.7	COG3352	Archaellum component FlaC	157
2904409335	263	57.32	96	199	56	145	5.3e-04	6.5	COG3352	Archaellum component FlaC	157
2904409336	799	98.25	9	799	12	797	0.0e+00	651	COG3451	Type IV secretory pathway, VirB4 component	796
2904409337	92	83.81	1	92	8	95	1.2e-25	84.3	COG3702	Type IV secretory pathway, VirB3 components	105
2904409338	96	76.85	1	96	19	101	3.0e-22	73.2	COG3838	Type IV secretory pathway, VirB2 components (pilins)	108
2904409341	160	67.86	1	160	73	224	4.8e-52	170.9	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
2904409343	288	95.08	38	286	1	251	1.0e-49	163.9	COG1192	Cellulose biosynthesis protein BcsQ	259
2904409344	333	85.98	18	312	4	230	1.6e-36	119.2	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2904409348	237	35.59	13	200	43	84	1.5e-03	8.5	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2904409350	72	4.44	4	27	158	165	9.8e-01	2.9	COG1439	rRNA maturation endonuclease Nob1	177
2904409350	72	15	21	68	137	163	9.8e-01	4.8	COG1439	rRNA maturation endonuclease Nob1	177
2904409351	95	91.78	24	92	3	69	1.2e-16	55	COG2608	Copper chaperone CopZ	71
2904409353	136	94.7	6	121	1	125	2.4e-27	90	COG0789	DNA-binding transcriptional regulator, MerR family	124
2904409354	86	77.53	2	85	2	70	1.5e-11	39	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
2904409355	111	94.95	1	105	3	96	1.5e-16	54.8	COG3668	Plasmid stabilization system protein ParE	98
2904409358	59	33.33	1	57	6	44	5.1e-08	27.7	COG2963	Transposase and inactivated derivatives	116
2904409360	140	80.8	11	134	7	107	3.4e-15	50.7	COG3293	Transposase	124
2904409361	126	67.2	8	121	40	123	8.5e-10	33.5	COG3293	Transposase	124
2904409366	361	22.86	62	360	229	495	9.5e-08	23.7	COG1196	Chromosome segregation ATPase	1163
2904409367	188	91.59	1	188	1	207	1.2e-56	186.2	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2904409368	94	98.8	1	87	1	82	6.5e-20	65.2	COG3905	Predicted transcriptional regulator	83
2904409369	98	88.89	1	98	3	90	2.7e-18	60.8	COG3668	Plasmid stabilization system protein ParE	98
2904409370	1014	10.62	320	379	31	54	2.9e-13	11.4	COG1136	ABC-type lipoprotein export system, ATPase component	226
2904409370	1014	34.07	874	973	136	212	2.9e-13	26.6	COG1136	ABC-type lipoprotein export system, ATPase component	226
2904409372	899	16.83	470	538	217	267	6.3e-18	33.7	COG0863	DNA modification methylase	302
2904409372	899	39.93	169	340	13	133	6.3e-18	23.4	COG0863	DNA modification methylase	302
2904409373	96	94.95	1	96	4	97	7.9e-24	78.5	COG3668	Plasmid stabilization system protein ParE	98
2904409374	88	91.57	2	83	3	78	6.9e-25	81	COG3905	Predicted transcriptional regulator	83
2904409381	852	32.02	96	335	7	242	4.2e-36	5.6	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
2904409381	852	54.41	359	850	323	723	4.2e-36	113.3	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
2904409383	167	34.02	22	159	124	205	8.9e-10	33.2	COG4083	Exosortase/Archaeosortase	239
2904409386	224	11.92	1	197	606	707	3.2e-13	43.5	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904409389	371	33.53	1	357	427	713	6.6e-24	77.3	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2904409390	44	21.15	1	43	158	201	1.1e-04	16.4	COG0288	Carbonic anhydrase	207
2904409391	130	61.07	25	130	39	118	1.1e-11	39	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2904409396	208	49.1	3	204	42	178	1.5e-14	48.9	COG0500	SAM-dependent methyltransferase	257
2904409398	130	96.26	1	118	3	105	1.3e-20	67.5	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2904409400	821	49.5	7	151	39	138	2.8e-07	23.6	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2904409400	821	64.71	333	821	219	647	7.8e-127	418.1	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2904409401	145	90.98	1	140	5	125	2.4e-26	86.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2904409402	570	67.51	263	565	122	387	9.4e-54	177.9	COG0642	Signal transduction histidine kinase	336
2904409404	331	98.71	2	304	3	307	1.3e-95	314.3	COG4261	Predicted acyltransferase, LPLAT superfamily	309
2904409405	99	62.84	1	96	36	128	1.2e-14	48.6	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2904409406	213	92.04	2	197	11	195	1.7e-25	84.1	COG4648	Uncharacterized membrane protein	201
2904409407	89	95.06	3	88	4	80	1.2e-15	51.7	COG0236	Acyl carrier protein	80
2904409408	350	54.41	210	325	10	83	5.6e-06	19.7	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2904409409	426	82.06	2	418	2	335	1.5e-48	160.1	COG0644	Dehydrogenase (flavoprotein)	396
2904409410	402	95.8	107	386	13	286	2.6e-103	339.2	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2904409411	261	98.04	1	253	1	250	1.1e-91	300.7	COG3484	Predicted proteasome-type protease	255
2904409412	486	96.52	3	483	8	478	0.0e+00	645.2	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
2904409413	325	98.4	1	312	1	308	5.6e-74	243.6	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2904409415	164	97.35	1	156	4	150	8.6e-48	156.3	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
2904409418	401	99.15	1	401	2	351	2.6e-114	375.8	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2904409421	317	76.25	243	309	16	76	8.1e-19	60.6	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2904409421	317	92.48	8	134	7	129	9.3e-40	129	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2904409422	1124	63.74	915	1054	7	122	1.2e-12	41.6	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2904409422	1124	81.98	536	906	67	389	1.1e-75	250	COG0642	Signal transduction histidine kinase	336
2904409425	431	98.63	11	389	5	365	2.1e-69	228.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2904409426	547	44.76	49	188	61	218	2.8e-05	2.3	COG1413	HEAT repeat	335
2904409426	547	45.61	133	262	65	225	2.8e-05	17.5	COG1413	HEAT repeat	335
2904409426	547	98.01	252	545	6	300	6.1e-100	328.6	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2904409427	361	97.21	10	360	8	321	2.1e-90	297.4	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2904409428	274	96.48	22	274	6	252	1.2e-125	412.2	COG4674	ABC-type uncharacterized transport system, ATPase component	249
2904409429	259	29.11	188	259	168	236	8.6e-89	50.5	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2904409429	259	78.06	1	190	3	187	8.6e-89	239.2	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2904409430	194	93.03	1	194	13	199	8.5e-45	146.9	COG2370	Hydrogenase/urease accessory protein HupE	201
2904409431	274	98.53	7	272	5	272	2.1e-68	225	COG0829	Urease accessory protein UreH	269
2904409432	100	99	1	100	1	99	1.9e-53	173.1	COG0831	Urease gamma subunit	100
2904409433	101	95.28	1	101	1	101	4.8e-51	165.6	COG0832	Urease beta subunit	106
2904409434	567	100	1	567	1	569	0.0e+00	1078.3	COG0804	Urease alpha subunit	568
2904409436	146	87.18	2	146	19	154	2.3e-44	144.9	COG2371	Urease accessory protein UreE	155
2904409437	229	97.82	6	229	6	229	4.7e-61	201	COG0830	Urease accessory protein UreF	229
2904409438	206	96.97	1	204	5	196	9.4e-79	257.7	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
2904409439	345	88.77	4	339	35	358	2.1e-105	346.7	COG1858	Cytochrome c peroxidase	364
2904409441	402	99.5	1	398	2	403	8.7e-128	421.1	COG0162	Tyrosyl-tRNA synthetase	401
2904409442	135	93.94	8	125	1	124	5.2e-25	82.5	COG0789	DNA-binding transcriptional regulator, MerR family	124
2904409444	159	11.39	2	152	745	877	3.1e-08	25.6	COG1196	Chromosome segregation ATPase	1163
2904409446	114	67.36	1	114	36	132	1.4e-18	61.3	COG4190	Predicted transcriptional regulator	144
2904409452	97	25.96	2	91	189	262	3.5e-08	27.5	COG1864	DNA/RNA endonuclease G, NUC1	281
2904409453	175	53.68	1	162	9	161	2.0e-20	67.5	COG1864	DNA/RNA endonuclease G, NUC1	281
2904409454	91	95.6	2	91	5	91	8.6e-12	39.6	COG3041	mRNA-degrading endonuclease (mRNA interferase) YafQ, toxin component of the YafQ-DinJ toxin-antitoxin module	91
2904409455	90	61.63	1	78	3	55	1.0e-05	19.2	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
2904409460	230	87.5	1	230	25	227	8.5e-41	134	COG3039	Transposase and inactivated derivatives, IS5 family	230
2904409464	642	71.59	11	261	17	205	7.3e-42	137.8	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2904409469	384	94.28	4	378	3	381	2.0e-95	314.1	COG0675	Transposase	364
2904409471	400	89.55	1	381	21	380	3.2e-77	254	COG0675	Transposase	364
2904409472	137	97.06	6	137	1	132	3.8e-45	147.7	COG1943	REP element-mobilizing transposase RayT	136
2904409473	151	36.39	4	138	55	173	2.6e-32	106.4	COG3344	Retron-type reverse transcriptase	328
2904409475	707	90.26	67	706	32	587	1.1e-113	374.7	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
2904409479	373	32.69	104	268	67	134	3.5e-06	4.2	COG3166	Tfp pilus assembly protein PilN	206
2904409479	373	39.9	206	371	84	166	3.5e-06	13.9	COG3166	Tfp pilus assembly protein PilN	206
2904409482	143	31.41	5	133	3	51	1.9e-08	28.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
2904409483	136	93.59	1	133	9	154	1.2e-24	81.9	COG2165	Type II secretory pathway, pseudopilin PulG	149
2904409484	409	98.99	5	408	3	396	4.2e-89	293.2	COG1459	Type II secretory pathway, component PulF	397
2904409485	575	95.67	73	572	21	506	0.0e+00	538.3	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2904409486	104	24.25	10	104	71	135	1.8e-04	15.1	COG4676	Uncharacterized conserved protein YfaP, DUF2135 family	268
2904409494	257	99.22	1	256	2	256	2.8e-87	286.5	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
2904409495	324	78.73	1	323	69	390	5.3e-76	250.2	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
2904409496	274	98.17	1	267	4	271	2.0e-95	313.5	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
2904409497	628	98.25	1	628	10	625	0.0e+00	843.7	COG3158	K+ transporter	627
2904409498	238	93.65	1	238	12	247	9.5e-82	268.4	COG0149	Triosephosphate isomerase	251
2904409499	126	87.1	1	99	1	81	1.1e-31	102.8	COG1314	Preprotein translocase subunit SecG	86
2904409501	346	90.86	1	343	28	365	0.0e+00	522.3	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
2904409502	114	93.81	13	109	6	96	6.4e-27	87.7	COG1862	Preprotein translocase subunit YajC	97
2904409503	614	99.62	75	614	2	522	0.0e+00	610.5	COG0342	Preprotein translocase subunit SecD	506
2904409504	312	93.83	2	306	8	296	3.1e-105	345.8	COG0341	Preprotein translocase subunit SecF	305
2904409505	296	41.72	70	284	204	387	7.5e-30	96.5	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
2904409506	236	48.82	17	165	27	129	2.6e-07	24.1	COG0177	Endonuclease III	211
2904409507	345	85.82	105	345	6	235	2.9e-45	148.6	COG1018	Ferredoxin-NADP reductase	266
2904409507	345	89.32	3	97	4	95	2.9e-10	33.3	COG0633	Ferredoxin	102
2904409508	554	96.88	1	554	4	562	0.0e+00	566.9	COG1151	Hydroxylamine reductase (hybrid-cluster protein)	576
2904409509	229	95.41	8	218	8	215	1.5e-35	116.8	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2904409510	297	97.39	3	297	4	302	8.9e-55	180.1	COG0492	Thioredoxin reductase	305
2904409513	262	66.78	8	260	51	241	5.8e-27	88.6	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2904409514	583	35.7	315	513	298	463	5.6e-42	74.1	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2904409514	583	68.39	1	307	13	330	5.6e-42	67.9	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2904409516	195	74.3	9	195	28	212	1.4e-36	120.2	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2904409517	798	19.02	711	794	275	344	4.0e-57	24.9	COG0457	Tetratricopeptide (TPR) repeat	291
2904409517	798	55.43	19	200	102	305	4.0e-57	49.7	COG0457	Tetratricopeptide (TPR) repeat	291
2904409517	798	64.67	511	713	105	342	4.0e-57	63.6	COG0457	Tetratricopeptide (TPR) repeat	291
2904409517	798	67.66	331	556	97	345	4.0e-57	42	COG0457	Tetratricopeptide (TPR) repeat	291
2904409517	798	76.36	131	372	63	343	4.0e-57	59.5	COG0457	Tetratricopeptide (TPR) repeat	291
2904409519	148	80.15	1	135	3	107	2.1e-42	138.8	COG1970	Large-conductance mechanosensitive channel	130
2904409520	320	96.66	2	295	11	299	2.8e-87	287	COG1230	Co/Zn/Cd efflux system component	296
2904409524	740	85.66	2	598	4	451	1.5e-98	324.7	COG0286	Type I restriction-modification system, DNA methylase subunit	489
2904409525	300	96.66	4	299	4	292	4.2e-60	197.6	COG4823	Abortive infection bacteriophage resistance protein	299
2904409527	436	44.2	1	173	192	370	1.1e-37	47.1	COG0732	Restriction endonuclease S subunit	391
2904409527	436	58.27	175	423	162	397	1.1e-37	75.7	COG0732	Restriction endonuclease S subunit	391
2904409528	377	93.35	27	368	23	359	2.9e-62	205	COG3177	Fic family protein	348
2904409529	1013	70.63	1	986	110	816	1.9e-109	361.6	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
2904409533	590	16.54	7	121	8	118	1.7e-29	47.1	COG0210	Superfamily I DNA or RNA helicase	655
2904409533	590	71.39	108	586	157	635	1.7e-29	43.1	COG0210	Superfamily I DNA or RNA helicase	655
2904409535	62	33.14	1	61	97	152	9.0e-04	13.3	COG4639	Predicted kinase	168
2904409539	79	23.94	1	74	215	282	2.9e-10	34.4	COG2801	Transposase InsO and inactivated derivatives	232
2904409544	160	59.72	1	139	75	203	2.3e-42	139.1	COG3316	Transposase (or an inactivated derivative)	215
2904409545	73	30.09	2	73	3	67	7.4e-23	75.6	COG3316	Transposase (or an inactivated derivative)	215
2904409547	466	96.96	22	466	2	447	1.1e-94	312.1	COG1538	Outer membrane protein TolC	457
2904409549	360	87.99	2	359	28	364	2.1e-74	244.8	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
2904409550	471	27.27	1	80	44	118	2.1e-103	15.1	COG1760	L-serine deaminase	262
2904409550	471	99.64	168	463	1	274	2.1e-103	322.5	COG1760	L-serine deaminase	262
2904409551	498	91.74	8	498	39	482	8.2e-62	203.7	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2904409555	218	98.1	1	210	2	208	1.8e-86	282.9	COG0177	Endonuclease III	211
2904409556	237	98.58	4	215	3	211	1.0e-88	290.5	COG4660	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfE subunit	212
2904409557	214	98.46	4	199	3	194	3.0e-62	204.2	COG4659	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit	195
2904409558	343	99.11	2	343	2	336	2.6e-125	412.6	COG4658	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfD subunit	338
2904409559	560	98.11	4	532	2	520	0.0e+00	577.5	COG4656	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfC subunit	529
2904409560	179	87.37	1	178	5	177	1.2e-77	254.4	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
2904409561	193	99.48	1	193	1	192	2.9e-97	318.8	COG4657	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfA subunit	193
2904409562	261	45	1	254	46	261	1.6e-56	186.7	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2904409563	146	97.5	28	146	1	117	3.0e-44	144.7	COG1734	RNA polymerase-binding transcription factor DksA	120
2904409564	385	98.99	5	385	2	393	7.3e-117	384.9	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2904409565	201	74.3	9	200	30	214	3.7e-33	108.9	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2904409566	516	92.04	13	459	26	453	1.4e-41	130.2	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2904409567	305	84.97	5	304	22	264	1.1e-36	120.5	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2904409569	139	100	1	138	1	137	7.3e-45	146.4	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
2904409572	238	79.31	30	219	15	175	6.9e-39	127	COG3271	Predicted double-glycine peptidase	201
2904409574	474	94.65	35	471	20	461	1.2e-120	397.5	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2904409577	139	32.79	23	138	28	127	7.3e-30	98.8	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2904409578	463	98.3	30	463	2	406	0.0e+00	525.7	COG0004	Ammonia channel protein AmtB	409
2904409579	112	100	1	112	1	112	6.1e-50	162.7	COG0347	Nitrogen regulatory protein PII	112
2904409580	83	76.7	1	83	10	88	6.4e-26	84.9	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
2904409581	505	98.78	15	503	2	487	0.0e+00	656.8	COG0606	Predicted ATPase with chaperone activity	490
2904409582	669	98.81	3	649	1	663	0.0e+00	718.1	COG0210	Superfamily I DNA or RNA helicase	655
2904409584	322	80.6	40	321	52	321	3.3e-32	106.6	COG0582	Integrase	309
2904409591	78	50	3	78	54	119	3.1e-07	25.3	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
2904409594	680	98.39	5	680	11	682	0.0e+00	1096.3	COG4930	Predicted ATP-dependent Lon-type protease	683
2904409596	324	26.35	21	76	94	132	1.9e-04	3.4	COG5612	Uncharacterized membrane protein	148
2904409596	324	47.3	181	273	47	116	1.9e-04	9.8	COG5612	Uncharacterized membrane protein	148
2904409598	147	71.54	8	134	15	107	3.2e-03	13.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2904409600	599	88.83	4	569	22	490	7.0e-92	302.1	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
2904409601	536	14.14	186	528	83	139	1.2e-06	8.8	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904409601	536	30.27	48	211	131	252	1.2e-06	16.7	COG3391	DNA-binding beta-propeller fold protein YncE	381
2904409604	59	23.23	1	59	196	254	2.5e-21	70.7	COG1117	ABC-type phosphate transport system, ATPase component	253
2904409606	292	97.67	19	284	6	257	2.8e-51	168.3	COG0688	Phosphatidylserine decarboxylase	239
2904409609	562	34.26	309	524	220	367	3.6e-63	133.3	COG0001	Glutamate-1-semialdehyde aminotransferase	432
2904409609	562	40.97	114	297	35	211	3.6e-63	71.4	COG0001	Glutamate-1-semialdehyde aminotransferase	432
2904409611	778	99.52	10	778	3	622	0.0e+00	669.2	COG3211	Secreted phosphatase, PhoX family	616
2904409612	255	94.59	1	252	8	252	3.9e-84	276.6	COG0805	Sec-independent protein secretion pathway component TatC	255
2904409613	107	70.21	1	96	1	66	8.3e-19	62.3	COG1826	Sec-independent protein translocase protein TatA	94
2904409614	71	52.13	1	68	2	50	9.0e-20	65.6	COG1826	Sec-independent protein translocase protein TatA	94
2904409615	510	5.3	156	223	218	250	1.3e-40	36.4	COG3211	Secreted phosphatase, PhoX family	616
2904409615	510	19.26	31	155	21	140	1.3e-40	19.3	COG3211	Secreted phosphatase, PhoX family	616
2904409615	510	50.24	212	510	287	599	1.3e-40	79.9	COG3211	Secreted phosphatase, PhoX family	616
2904409618	200	90.86	11	191	15	183	1.5e-35	116.7	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
2904409619	123	85.27	5	120	18	127	3.3e-23	76.2	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2904409620	973	4.52	14	27	2	11	2.9e-16	1.9	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2904409620	973	59.28	25	172	85	215	2.9e-16	54.7	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2904409620	973	97.41	165	971	8	760	0.0e+00	676	COG1554	Trehalose and maltose hydrolase (possible phosphorylase)	772
2904409621	675	97	36	662	10	592	0.0e+00	716.1	COG0465	ATP-dependent Zn proteases	596
2904409623	324	54.02	5	324	57	318	9.0e-59	193.8	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2904409624	168	32.16	1	165	329	484	5.4e-32	105.6	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2904409625	215	22.67	130	210	219	286	7.1e-42	91.9	COG4974	Site-specific recombinase XerD	300
2904409625	215	23.33	1	107	139	208	7.1e-42	48	COG4974	Site-specific recombinase XerD	300
2904409629	260	62.98	84	257	80	227	4.4e-29	95.8	COG4271	Predicted nucleotide-binding protein containing TIR -like domain	233
2904409630	248	64.16	3	246	44	222	1.7e-12	42.4	COG0500	SAM-dependent methyltransferase	257
2904409632	439	94.48	8	317	11	318	7.1e-52	170.7	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2904409633	488	95.85	1	465	7	468	3.4e-33	109.2	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2904409634	363	49.82	101	357	42	180	4.0e-18	60.5	COG0500	SAM-dependent methyltransferase	257
2904409635	357	81.89	1	355	3	296	1.6e-25	85	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2904409636	242	65.95	3	240	49	232	5.4e-17	56.9	COG0500	SAM-dependent methyltransferase	257
2904409637	624	93.8	1	603	23	536	5.2e-114	375.4	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2904409639	416	96.82	2	362	11	406	6.0e-35	115.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904409640	375	94.87	6	356	15	402	4.5e-45	148.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904409641	379	86.31	8	374	55	407	8.0e-46	151.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904409642	365	74.37	5	352	4	270	1.9e-26	88.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2904409643	175	44.44	2	171	55	178	1.3e-21	72	COG0500	SAM-dependent methyltransferase	257
2904409644	237	51.25	4	227	54	196	9.7e-13	43.3	COG0500	SAM-dependent methyltransferase	257
2904409645	271	54.87	2	267	3	199	2.9e-26	87.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2904409647	395	57.7	55	390	172	407	2.6e-40	133.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904409648	520	60.37	154	506	147	443	5.5e-27	86.5	COG5421	Transposase	480
2904409651	404	97.07	19	400	11	407	3.4e-51	169.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2904409652	151	98.65	1	146	3	148	5.5e-33	108.7	COG0394	Protein-tyrosine-phosphatase	139
2904409653	765	21.29	20	154	19	117	9.9e-56	71.2	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2904409653	765	53.98	219	491	206	456	9.9e-56	108.1	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2904409653	765	81.12	516	763	37	268	2.1e-45	148.9	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2904409655	73	29.17	2	73	4	66	1.0e-21	72.1	COG3316	Transposase (or an inactivated derivative)	215
2904409656	97	40.74	1	97	75	162	2.0e-32	107.1	COG3316	Transposase (or an inactivated derivative)	215
2904409657	89	43.2	6	84	70	123	1.0e-07	26.8	COG3293	Transposase	124
2904409658	268	96	6	143	2	121	6.3e-40	78.3	COG3293	Transposase	124
2904409658	268	97.6	132	260	2	123	6.3e-40	57.3	COG3293	Transposase	124
2904409660	128	67.2	11	124	7	90	2.6e-13	45	COG3293	Transposase	124
2904409661	587	11.13	166	342	384	437	5.8e-17	7.1	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2904409661	587	41.03	326	582	247	445	5.8e-17	47.7	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2904409662	349	94.17	1	219	1	210	9.2e-68	222.3	COG5634	Uncharacterized protein YukJ	223
2904409663	170	74.26	1	170	5	180	2.1e-48	159.7	COG1183	Phosphatidylserine synthase	234
2904409664	400	66.5	21	389	129	390	3.1e-68	225.5	COG0642	Signal transduction histidine kinase	336
2904409667	635	90.66	407	635	7	239	8.9e-36	116.5	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2904409667	635	95.08	220	407	3	176	1.9e-24	81.2	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2904409668	218	63.35	11	186	69	189	3.9e-27	89.7	COG3672	Predicted transglutaminase-like cysteine proteinase	191
2904409672	534	88.57	19	534	65	560	2.0e-78	259	COG2831	Hemolysin activation/secretion protein	554
2904409674	604	68.06	362	600	68	214	1.2e-39	126.1	COG0811	Biopolymer transport protein ExbB/TolQ	216
2904409675	134	91.37	1	133	10	136	1.9e-34	113.2	COG0848	Biopolymer transport protein ExbD	137
2904409676	220	68.25	18	219	81	267	1.4e-09	31.6	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2904409678	248	36.85	4	182	15	171	4.2e-06	20.1	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
2904409680	515	88.97	76	515	26	404	7.4e-44	144.5	COG3746	Phosphate-selective porin	426
2904409681	317	37.66	1	164	3	147	7.9e-82	147.7	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2904409681	317	37.92	158	315	215	360	7.9e-82	120.3	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2904409683	164	71.92	20	162	40	144	2.8e-29	96.4	COG0071	Molecular chaperone IbpA, HSP20 family	146
2904409684	306	99.33	3	301	1	295	2.6e-109	359.6	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
2904409687	291	81.17	19	287	1	250	2.0e-73	241.5	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
2904409688	405	99.52	1	404	2	413	0.0e+00	470.1	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2904409689	152	90.54	1	148	13	146	9.1e-43	140.1	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2904409690	651	91.18	30	442	31	454	3.4e-19	55.9	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2904409691	612	98.14	8	599	6	586	0.0e+00	448.1	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2904409692	277	96.51	2	262	4	252	9.3e-77	252.6	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
2904409693	194	97.87	4	190	2	185	3.0e-79	259.5	COG2818	3-methyladenine DNA glycosylase Tag	188
2904409696	1036	99.22	1	1021	2	1023	0.0e+00	1220.8	COG3696	Cu/Ag efflux pump CusA	1027
2904409697	363	87.69	3	357	34	375	1.9e-29	97.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2904409698	416	69.13	36	410	111	428	1.1e-14	47.5	COG1538	Outer membrane protein TolC	457
2904409701	319	80.6	6	311	62	331	8.5e-99	324.8	COG1313	Uncharacterized Fe-S protein PflX, radical SAM superfamily	335
2904409702	180	56.25	18	175	58	156	1.5e-05	18.8	COG1818	tRNA(Ser,Leu) C12 N-acetylase TAN1, contains THUMP domain	175
2904409704	221	99.05	1	209	1	208	3.0e-80	263.2	COG2808	Predicted FMN-binding regulatory protein PaiB	209
2904409705	169	76.92	7	127	3	102	8.7e-13	41.6	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
2904409708	294	45.25	14	180	12	111	3.0e-05	16.4	COG2755	Lysophospholipase L1 or related esterase	216
2904409710	480	61.85	212	464	91	244	4.7e-18	59.5	COG1651	Protein-disulfide isomerase	244
2904409711	134	33.76	1	134	261	393	1.5e-71	235.6	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2904409713	125	83.56	46	119	13	73	8.8e-20	64.8	COG0690	Preprotein translocase subunit SecE	73
2904409714	177	97.81	1	177	3	181	4.4e-67	219.9	COG0250	Transcription antitermination factor NusG	178
2904409715	143	99.29	2	143	1	140	2.9e-65	213.1	COG0080	Ribosomal protein L11	141
2904409716	231	99.13	1	227	1	228	4.2e-94	308.9	COG0081	Ribosomal protein L1	228
2904409717	175	96.59	1	174	6	175	9.2e-51	166.4	COG0244	Ribosomal protein L10	175
2904409718	124	100	1	124	1	125	2.2e-49	161.6	COG0222	Ribosomal protein L7/L12	124
2904409719	1358	99.45	1	1358	3	1082	0.0e+00	1518.3	COG0085	DNA-directed RNA polymerase, beta subunit/140 kD subunit	1060
2904409720	1401	4.07	889	962	418	450	0.0e+00	9.7	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2904409720	1401	6.29	1303	1391	696	746	0.0e+00	18.2	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2904409720	1401	99.63	11	853	3	810	0.0e+00	988.3	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2904409721	199	54.81	104	195	42	115	4.5e-52	100.2	COG2863	Cytochrome c553	121
2904409721	199	70.37	2	115	21	115	4.5e-52	69	COG2863	Cytochrome c553	121
2904409722	187	90.74	16	172	12	158	3.3e-44	144.6	COG4067	Uncharacterized conserved protein	162
2904409724	300	11.11	137	185	207	241	4.9e-12	3.6	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2904409724	300	12.7	204	278	249	288	4.9e-12	18.4	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2904409724	300	18.73	9	97	115	173	4.9e-12	14.5	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2904409725	362	95.38	6	347	15	324	1.7e-58	192.7	COG0226	ABC-type phosphate transport system, periplasmic component	318
2904409726	459	97.77	143	458	7	313	2.9e-99	326	COG0573	ABC-type phosphate transport system, permease component	310
2904409727	437	88.1	161	437	36	294	5.8e-83	273	COG0581	ABC-type phosphate transport system, permease component	292
2904409728	200	78.35	1	200	56	254	3.4e-99	325.8	COG1117	ABC-type phosphate transport system, ATPase component	253
2904409729	230	91.02	1	229	7	229	2.5e-47	155.8	COG0704	Phosphate uptake regulator	240
2904409731	95	28.57	1	93	122	215	8.5e-28	92.2	COG0724	 RNA recognition motif (RRM) domain	306
2904409732	311	99.37	14	306	2	315	1.2e-61	203	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2904409733	281	88.98	9	266	11	236	6.8e-79	259.1	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
2904409734	315	98.29	6	302	5	291	5.7e-94	309.2	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2904409735	241	98.8	3	241	3	250	4.0e-84	276.3	COG1496	Copper oxidase (laccase) domain	249
2904409736	277	90.07	1	257	20	264	8.9e-45	147.6	COG0428	Zinc transporter ZupT	266
2904409737	199	98.97	1	198	1	193	5.4e-73	239.2	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
2904409738	48	24.04	2	48	3	52	2.0e-06	22.3	COG0288	Carbonic anhydrase	207
2904409739	331	34.29	205	331	228	347	5.4e-57	19.4	COG3839	ABC-type sugar transport system, ATPase component	338
2904409739	331	58.29	5	215	6	209	5.4e-57	168.5	COG3839	ABC-type sugar transport system, ATPase component	338
2904409740	230	97.8	2	228	2	223	1.6e-79	260.8	COG4662	ABC-type tungstate transport system, periplasmic component	227
2904409741	581	99.43	1	575	1	524	0.0e+00	715.6	COG0442	Prolyl-tRNA synthetase	500
2904409742	398	98.23	3	398	5	393	9.4e-94	309	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2904409743	271	98.53	1	271	3	270	4.7e-100	329.1	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
2904409745	466	20.47	337	465	431	543	5.3e-46	56.3	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2904409745	466	48.19	65	336	104	369	5.3e-46	93.2	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2904409748	279	87.01	14	278	38	305	1.3e-20	68.3	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
2904409749	224	91.42	1	224	21	265	1.2e-44	146.1	COG1912	S-adenosylmethionine hydrolase (SAM-hydroxide adenosyltransferase)	268
2904409750	249	95.37	1	249	4	250	4.1e-87	286.4	COG0805	Sec-independent protein secretion pathway component TatC	255
2904409751	108	81.91	1	105	1	77	2.0e-21	70.6	COG1826	Sec-independent protein translocase protein TatA	94
2904409752	67	58.51	1	67	2	56	7.4e-20	65.9	COG1826	Sec-independent protein translocase protein TatA	94
2904409753	126	96.83	2	126	2	123	4.6e-50	163.2	COG0853	Aspartate 1-decarboxylase	126
2904409754	269	94.24	1	268	7	268	2.7e-98	323	COG0294	Dihydropteroate synthase	274
2904409755	327	99.06	4	323	2	317	5.3e-122	401.3	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
2904409756	206	100	1	206	1	210	2.0e-69	228	COG0522	Ribosomal protein S4 or related protein	205
2904409757	118	96.69	1	118	1	117	3.8e-52	169	COG0099	Ribosomal protein S13	121
2904409758	441	96.59	4	437	12	436	0.0e+00	519.4	COG0201	Preprotein translocase subunit SecY	436
2904409759	144	98.05	1	144	1	151	1.5e-43	143.1	COG0200	Ribosomal protein L15	152
2904409760	61	98.18	6	60	1	54	1.2e-20	66.3	COG1841	Ribosomal protein L30/L7E	55
2904409761	172	85.33	2	169	22	178	2.5e-62	203.7	COG0098	Ribosomal protein S5	181
2904409762	117	96.03	1	117	6	126	5.9e-38	124.7	COG0256	Ribosomal protein L18	125
2904409763	177	98.88	1	177	1	177	1.8e-66	217.7	COG0097	Ribosomal protein L6P/L9E	178
2904409764	129	97.74	1	129	3	132	2.0e-47	154.9	COG0096	Ribosomal protein S8	132
2904409765	101	96.72	41	101	3	61	1.8e-25	83.4	COG0199	Ribosomal protein S14	61
2904409766	179	98.89	1	179	1	178	1.1e-84	277.1	COG0094	Ribosomal protein L5	180
2904409767	105	97.22	1	104	3	107	1.4e-31	103.5	COG0198	Ribosomal protein L24	104
2904409768	122	100	1	122	1	123	4.2e-59	192.4	COG0093	Ribosomal protein L14	122
2904409769	86	91.95	1	86	6	85	8.8e-33	106.8	COG0186	Ribosomal protein S17	87
2904409770	64	92.65	1	63	1	63	9.6e-24	77.7	COG0255	Ribosomal protein L29	69
2904409771	137	92.62	1	136	2	139	4.2e-60	196.2	COG0197	Ribosomal protein L16/L10AE	146
2904409772	223	86.27	12	222	2	202	1.3e-94	310.2	COG0092	Ribosomal protein S3	233
2904409773	111	90.6	1	111	12	146	2.9e-39	128.7	COG0091	Ribosomal protein L22	120
2904409774	90	94.62	1	90	1	88	1.3e-42	137	COG0185	Ribosomal protein S19	93
2904409775	275	99.64	1	274	1	274	1.3e-121	399.7	COG0090	Ribosomal protein L2	275
2904409776	97	94.68	6	97	2	90	2.0e-31	103	COG0089	Ribosomal protein L23	94
2904409777	204	88.94	8	204	17	209	3.3e-62	204.1	COG0088	Ribosomal protein L4	214
2904409778	201	92.95	1	201	11	221	3.7e-71	234	COG0087	Ribosomal protein L3	218
2904409779	103	97.12	1	103	2	102	2.5e-47	153.8	COG0051	Ribosomal protein S10	104
2904409780	31	7.87	1	31	364	394	1.1e-12	40.7	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2904409781	180	52.82	34	180	50	180	4.0e-51	168.7	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
2904409782	119	91.3	1	113	2	106	2.1e-43	141.2	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
2904409783	260	59.45	5	255	38	254	1.2e-26	88	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2904409784	458	96.35	14	449	13	434	2.7e-62	205.2	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
2904409785	571	27.89	508	569	90	130	3.1e-22	26.1	COG1388	LysM repeat	124
2904409785	571	37.41	386	521	81	135	3.1e-22	45.9	COG1388	LysM repeat	124
2904409786	243	36.2	17	226	120	220	6.7e-07	24.5	COG0500	SAM-dependent methyltransferase	257
2904409787	162	93.59	2	156	3	148	4.3e-58	190.1	COG0328	Ribonuclease HI	154
2904409788	237	92.91	1	237	17	252	1.0e-66	220	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2904409790	215	98.58	2	210	3	210	7.9e-60	196.4	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2904409792	485	97.28	2	485	4	503	1.7e-112	371.1	COG0168	Trk-type K+ transport system, membrane component	499
2904409793	191	96.09	14	190	7	178	3.2e-55	180.9	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
2904409794	145	98.11	1	145	3	158	2.1e-29	97.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2904409796	629	99.44	1	522	3	534	0.0e+00	578.3	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2904409798	155	98.09	1	155	1	154	4.3e-63	206.4	COG2193	Bacterioferritin (cytochrome b1)	157
2904409799	69	87.3	1	68	1	55	7.8e-20	64.2	COG2906	Bacterioferritin-associated ferredoxin	63
2904409802	962	99.68	1	940	3	940	0.0e+00	1483.8	COG0178	Excinuclease UvrABC ATPase subunit	935
2904409803	463	94.68	8	399	13	386	4.4e-40	131.7	COG2814	Predicted arabinose efflux permease, MFS family	394
2904409804	159	99.42	3	159	2	171	4.6e-55	181.2	COG0629	Single-stranded DNA-binding protein	167
2904409805	92	90.38	1	91	11	104	1.0e-07	23	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2904409807	243	88.99	18	225	15	208	5.2e-23	76	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2904409808	203	97.52	9	198	5	201	8.8e-51	166.6	COG1573	Uracil-DNA glycosylase	202
2904409809	428	82	301	428	10	132	1.4e-09	32.2	COG1959	DNA-binding transcriptional regulator, IscR family	150
2904409809	428	90.1	9	299	12	284	4.6e-54	177.8	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2904409810	42	16.8	1	42	1	43	5.4e-16	53.5	COG0121	Predicted glutamine amidotransferase	252
2904409813	270	92.58	4	270	12	273	3.0e-14	46.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2904409814	596	79.56	1	565	114	728	7.5e-109	356.7	COG4993	Glucose dehydrogenase	773
2904409815	118	31.05	16	118	154	239	1.1e-14	49.2	COG2857	Cytochrome c1	250
2904409816	174	79.88	17	161	20	150	3.0e-22	73.9	COG2010	Cytochrome c, mono- and diheme variants	150
2904409817	337	74.85	6	329	66	321	7.3e-32	105.1	COG0668	Small-conductance mechanosensitive channel	316
2904409819	177	62.05	6	166	11	149	2.6e-36	119.2	COG2323	Uncharacterized membrane protein YcaP, DUF421 family	224
2904409820	145	38.43	3	136	166	268	2.3e-11	35.5	COG1834	N-Dimethylarginine dimethylaminohydrolase	267
2904409821	534	97.23	7	521	11	466	4.8e-69	226.8	COG0277	FAD/FMN-containing dehydrogenase	459
2904409822	517	81.33	3	463	17	421	8.5e-42	138.2	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
2904409823	434	92.54	66	426	7	279	4.3e-07	24.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904409824	173	71.05	7	173	45	179	1.4e-37	123.6	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2904409825	164	93.75	1	160	4	153	6.8e-17	56.3	COG0680	Ni,Fe-hydrogenase maturation factor	160
2904409826	431	96.26	5	431	3	439	4.2e-87	287.4	COG3259	Coenzyme F420-reducing hydrogenase, alpha subunit	441
2904409827	259	87.55	2	239	2	219	3.1e-47	155.3	COG1941	Coenzyme F420-reducing hydrogenase, gamma subunit	247
2904409828	277	98.05	2	270	5	256	3.3e-52	171.5	COG0543	NAD(P)H-flavin reductase	252
2904409829	365	62.9	215	365	33	110	3.1e-09	28.9	COG1145	Ferredoxin	99
2904409830	320	88.01	43	320	29	263	3.9e-17	53.7	COG0725	ABC-type molybdate transport system, periplasmic component	258
2904409831	184	80.53	54	183	21	111	3.0e-09	31.1	COG1416	Intracellular sulfur oxidation protein, DsrE/DsrF family	112
2904409834	133	17.47	11	125	258	322	3.7e-03	10.8	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
2904409838	406	83.84	3	406	50	355	3.0e-84	277.5	COG1858	Cytochrome c peroxidase	364
2904409841	520	89.49	4	399	3	385	1.0e-107	354.7	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
2904409843	193	85.65	2	193	16	194	6.1e-21	70.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904409844	138	21.64	6	118	84	162	1.4e-05	19	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2904409846	491	98.77	4	490	6	485	0.0e+00	620	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
2904409849	302	97.29	10	286	7	293	1.1e-51	170.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904409850	142	77.27	50	126	7	74	2.0e-04	15.3	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2904409851	185	91.94	1	179	12	182	4.7e-33	108.6	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
2904409853	130	78.86	14	124	19	115	6.5e-18	59.1	COG0818	Diacylglycerol kinase	123
2904409854	94	14.21	1	93	12	91	7.2e-20	65.4	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2904409855	561	95.26	1	262	12	272	1.3e-65	215.5	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
2904409858	156	98.06	1	155	4	155	3.9e-48	157.9	COG5528	Uncharacterized membrane protein	155
2904409859	426	79.71	1	277	1	220	1.9e-43	143.1	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2904409860	175	95.48	1	175	2	170	9.1e-48	157	COG1510	DNA-binding transcriptional regulator GbsR, MarR family	177
2904409861	341	99.7	1	335	1	331	5.6e-122	401.2	COG3588	Fructose-bisphosphate aldolase class 1	332
2904409862	144	94.33	1	135	7	139	1.9e-39	129.4	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2904409863	293	68.66	67	280	65	213	1.7e-59	195.3	COG5637	Uncharacterized membrane protein	217
2904409864	389	99.72	1	389	2	353	1.8e-120	396.3	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2904409868	54	94.44	1	53	1	51	6.4e-20	65.6	COG5487	Uncharacterized membrane protein YtjA, UPF0391 family	54
2904409869	115	40	3	38	17	36	1.1e-03	12.7	COG1552	Ribosomal protein L40E	50
2904409870	152	63.59	2	145	73	210	1.6e-18	61.2	COG5637	Uncharacterized membrane protein	217
2904409876	355	98.53	1	347	4	339	3.5e-129	425.1	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2904409877	129	56.18	4	85	2	51	7.3e-09	30.3	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
2904409878	416	88.18	95	415	34	309	1.8e-59	195.2	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2904409879	260	99.25	1	259	2	267	6.4e-73	240.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2904409880	273	97.97	1	260	5	293	1.7e-51	169.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904409882	403	67.47	21	283	60	254	4.0e-48	158.2	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2904409883	101	40.48	2	81	34	84	3.3e-04	14.9	COG3245	Cytochrome c5	126
2904409885	311	92.81	13	160	8	136	9.1e-20	64.8	COG3415	Transposase	138
2904409886	454	88.38	11	447	18	420	1.5e-37	123.8	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2904409887	490	96.71	17	488	15	455	1.9e-90	298.2	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2904409888	1079	15.38	906	1024	48	99	3.9e-10	3.7	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2904409888	1079	34.62	28	332	153	269	3.9e-10	31.8	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2904409891	98	68.38	1	97	39	131	3.0e-25	83.4	COG1943	REP element-mobilizing transposase RayT	136
2904409892	382	59.7	69	370	141	380	2.6e-53	175.5	COG0675	Transposase	364
2904409898	161	67.41	3	161	74	224	3.5e-54	178	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
2904409899	146	15.84	2	118	155	231	7.2e-04	12.8	COG2509	Uncharacterized FAD-dependent dehydrogenase	486
2904409907	490	19.09	343	427	175	220	7.8e-08	11.2	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
2904409907	490	35.27	11	139	3	87	7.8e-08	13.1	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
2904409908	325	98.01	26	318	2	296	2.6e-51	169.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2904409909	212	99.5	1	198	1	201	1.2e-68	224.9	COG1182	FMN-dependent NADH-azoreductase	202
2904409910	286	98.57	7	286	4	279	8.2e-97	318.5	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2904409912	607	96.79	2	605	18	621	3.0e-120	397	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
2904409914	145	24.8	52	119	65	95	5.2e-11	13	COG0222	Ribosomal protein L7/L12	124
2904409914	145	25.6	2	55	64	95	5.2e-11	24.5	COG0222	Ribosomal protein L7/L12	124
2904409916	196	95.79	14	195	8	189	2.7e-46	152.1	COG2320	GrpB domain, predicted nucleotidyltransferase, UPF0157 family	185
2904409920	135	67.52	1	133	9	114	1.0e-25	84.3	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2904409921	215	94.12	4	215	3	162	1.8e-29	97.1	COG0262	Dihydrofolate reductase	167
2904409923	286	94.51	39	286	13	253	1.4e-81	267.7	COG2602	Beta-lactamase class D	254
2904409924	141	92.59	9	140	6	130	1.6e-27	90.4	COG3791	Uncharacterized conserved protein	133
2904409928	179	73.46	2	157	36	154	9.9e-10	33.4	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904409929	132	79.47	1	132	5	124	1.0e-31	104.6	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
2904409930	141	95.21	3	136	5	143	2.7e-10	36.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2904409931	93	28.46	28	93	76	110	2.2e-03	12.3	COG3795	Uncharacterized conserved protein	123
2904409935	51	53.85	1	51	43	91	3.5e-06	21.9	COG3041	mRNA-degrading endonuclease (mRNA interferase) YafQ, toxin component of the YafQ-DinJ toxin-antitoxin module	91
2904409938	287	95.45	1	286	2	253	1.4e-34	113.9	COG1192	Cellulose biosynthesis protein BcsQ	259
2904409939	332	71.21	31	261	3	190	1.7e-20	68.1	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2904409941	187	99.42	1	161	2	171	5.1e-46	151.7	COG0629	Single-stranded DNA-binding protein	167
2904409944	332	62.38	1	256	1	199	1.6e-12	40.7	COG5377	Phage-related protein, predicted endonuclease	319
2904409952	94	94.38	5	90	2	85	1.7e-16	54.8	COG1343	CRISPR/Cas system-associated endoribonuclease Cas2	89
2904409953	313	85.67	1	293	3	283	4.8e-65	214.1	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
2904409955	104	79.78	7	85	3	73	3.2e-16	53.9	COG1343	CRISPR/Cas system-associated endoribonuclease Cas2	89
2904409957	531	62.44	242	520	142	387	6.3e-29	96.5	COG0642	Signal transduction histidine kinase	336
2904409958	510	94.18	1	510	32	549	0.0e+00	512	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2904409959	176	26.54	15	145	4	89	1.0e-04	16.6	COG3115	Cell division protein ZipA, interacts with FtsZ	324
2904409963	94	91.92	1	94	4	94	2.6e-18	61	COG3668	Plasmid stabilization system protein ParE	98
2904409965	988	34.05	1	117	20	130	9.8e-117	35.5	COG4644	Transposase and inactivated derivatives, TnpA family	323
2904409965	988	99.39	625	950	1	324	9.8e-117	346.4	COG4644	Transposase and inactivated derivatives, TnpA family	323
2904409966	186	88.94	3	185	3	203	4.2e-49	161.7	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2904409967	327	94.46	1	318	10	333	3.2e-35	116.1	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
2904409969	121	92.42	4	121	1	122	6.8e-16	53.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
2904409970	107	20	1	92	365	455	3.2e-17	57	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2904409976	183	67.2	25	173	62	186	8.4e-20	66	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2904409977	199	89	1	199	12	197	7.8e-21	70.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2904409981	161	99.34	2	155	2	151	2.1e-65	213.8	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
2904409983	194	65.18	42	193	4	149	3.5e-38	125.4	COG2323	Uncharacterized membrane protein YcaP, DUF421 family	224
2904409984	130	67.19	5	128	41	126	4.5e-20	66.4	COG3755	Uncharacterized conserved protein YecT, DUF1311 family	127
2904409985	390	9.5	24	69	6	39	2.5e-21	3.9	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
2904409985	390	47.49	116	379	151	320	2.5e-21	65	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
2904409986	245	92.19	1	245	20	267	2.8e-78	257.5	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
2904409992	94	15.95	23	91	125	180	6.3e-04	13.2	COG5322	Predicted amino acid dehydrogenase	351
2904409996	301	74.24	20	300	35	279	7.2e-27	88.8	COG0714	MoxR-like ATPase	329
2904409998	218	47.08	1	185	36	188	3.1e-17	57	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2904409999	306	97.97	29	302	3	291	7.0e-39	128.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2904410000	166	61.11	4	138	54	152	2.4e-10	35.5	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2904410004	215	98.56	6	211	2	206	4.8e-51	167.3	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2904410006	208	63.4	9	181	8	130	8.3e-07	22.8	COG3068	Uncharacterized protein YjaG, DUF416 family	194
2904410007	328	11.11	134	159	89	105	8.0e-07	3.6	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2904410007	328	43.79	182	311	33	99	8.0e-07	19.8	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2904410008	118	22.38	5	118	43	106	1.1e-07	25.9	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2904410009	529	34.62	262	459	304	464	3.5e-37	87.6	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2904410009	529	36.56	75	255	163	332	3.5e-37	40.9	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2904410013	444	87.16	16	303	41	325	7.3e-65	213.3	COG3344	Retron-type reverse transcriptase	328
2904410015	167	25.6	95	166	35	98	2.6e-14	11.9	COG3063	Tfp pilus assembly protein PilF	250
2904410015	167	28.4	20	98	31	101	2.6e-14	40.3	COG3063	Tfp pilus assembly protein PilF	250
2904410016	191	67.07	10	191	45	211	1.4e-35	117.3	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2904410018	147	94.07	7	143	6	132	6.9e-32	104.6	COG3791	Uncharacterized conserved protein	133
2904410019	130	81.67	1	116	9	106	4.1e-34	111.2	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2904410020	85	14.41	1	83	13	79	1.2e-11	38.5	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2904410021	351	88.14	2	346	29	236	4.8e-07	24	COG3637	Opacity protein and related surface antigens	199
2904410022	317	77.31	2	298	35	293	7.1e-29	95.7	COG0582	Integrase	309
2904410023	378	87.79	3	376	35	379	2.8e-62	204.8	COG5659	SRSO17 transposase	385
2904410024	146	76.98	10	145	5	111	2.7e-11	37.6	COG3415	Transposase	138
2904410026	387	69.89	67	387	5	322	4.4e-94	310.1	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2904410027	345	60.57	4	345	167	507	4.4e-56	184.7	COG0659	Sulfate permease or related transporter, MFS superfamily	554
