gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
643772569	472	43.11	9	458	1	407	8.0e-113	401	COG0593	Chromosomal replication initiation ATPase DnaA	408
643772570	370	35.5	1	368	1	364	6.0e-77	281	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
643772573	176	24.53	18	175	3	161	4.0e-22	98	COG2323	Uncharacterized membrane protein YcaP, DUF421 family	224
643772574	571	28.26	196	563	64	407	2.0e-35	143	COG0840	Methyl-accepting chemotaxis protein	408
643772575	195	46.96	8	187	5	176	1.0e-42	166	COG0461	Orotate phosphoribosyltransferase	201
643772576	370	29.87	56	357	1	315	2.0e-42	167	COG0515	Serine/threonine protein kinase	384
643772578	984	40.6	9	301	10	298	1.0e-63	238	COG0258	5'-3' exonuclease	310
643772578	984	47.8	351	983	3	593	0.0e+00	657	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
643772581	464	23.79	4	248	26	254	2.0e-14	73.8	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
643772582	458	32.62	23	439	13	428	6.0e-78	284	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
643772584	791	52.57	13	736	10	743	0.0e+00	801	COG2183	Transcriptional accessory protein Tex/SPT6	780
643772586	550	22.94	58	546	3	454	6.0e-63	235	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
643772587	452	24.24	13	443	1	449	1.0e-51	197	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
643772589	445	27.53	56	438	4	312	9.0e-49	188	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
643772590	308	49.67	4	306	1	298	5.0e-61	228	COG1079	ABC-type uncharacterized transport system, permease component	304
643772591	353	42.94	1	345	1	345	4.0e-61	228	COG4603	ABC-type uncharacterized transport system, permease component	356
643772592	526	43.46	13	504	3	501	0.0e+00	471	COG3845	ABC-type uncharacterized transport system, ATPase component	501
643772593	261	33.33	6	260	1	249	6.0e-39	154	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
643772594	357	34.83	7	332	2	332	2.0e-63	236	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
643772595	338	35.71	65	329	2	240	2.0e-32	133	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
643772596	259	42.52	1	253	1	253	3.0e-57	215	COG1192	Cellulose biosynthesis protein BcsQ	259
643772597	247	33.47	3	246	1	243	3.0e-32	132	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
643772598	635	47.79	2	635	5	617	0.0e+00	743	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
643772602	359	41.79	27	355	15	342	1.0e-78	287	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
643772604	421	49.14	3	402	2	400	2.0e-94	339	COG1301	Na+/H+-dicarboxylate symporter	415
643772606	119	26.09	7	119	2	116	6.0e-11	59.8	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
643772607	347	24.76	50	346	9	308	3.0e-16	79.9	COG3391	DNA-binding beta-propeller fold protein YncE	381
643772613	195	37.29	22	192	1	177	1.0e-24	106	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643772615	236	24.64	54	235	9	213	3.0e-16	78.8	COG2755	Lysophospholipase L1 or related esterase	216
643772616	524	20.18	14	234	3	209	1.0e-06	48.4	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
643772617	672	39.74	1	536	1	530	0.0e+00	489	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
643772619	402	26.91	16	402	11	396	2.0e-35	143	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
643772621	397	26.75	87	393	12	306	5.0e-20	92.6	COG3391	DNA-binding beta-propeller fold protein YncE	381
643772622	102	27.17	1	92	3	94	3.0e-14	70	COG1359	Quinol monooxygenase YgiN	100
643772627	241	47.75	17	236	1	222	8.0e-76	276	COG1136	ABC-type lipoprotein export system, ATPase component	226
643772628	899	15.52	524	897	16	417	9.0e-13	69.8	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
643772629	117	30.1	13	115	2	104	3.0e-14	70.6	COG1695	DNA-binding transcriptional regulator, PadR family	138
643772630	295	26.14	31	293	23	282	2.0e-16	79.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643772632	188	33.33	13	185	14	173	2.0e-20	92	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
643772633	548	31.49	17	306	1	281	3.0e-45	176	COG0515	Serine/threonine protein kinase	384
643772634	194	20.73	1	192	6	192	6.0e-07	47.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643772635	263	26.64	5	261	4	264	1.0e-28	119	COG0300	Short-chain dehydrogenase	265
643772637	188	24.58	12	188	10	178	3.0e-06	45.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643772638	934	31.62	84	364	2	282	1.0e-41	165	COG0515	Serine/threonine protein kinase	384
643772640	112	46.3	5	112	6	113	3.0e-29	120	COG2361	Uncharacterized conserved protein, contains HEPN domain	117
643772641	107	50	26	103	21	97	2.0e-16	77.6	COG1669	Predicted nucleotidyltransferase	97
643772644	309	35.91	3	296	5	293	4.0e-60	225	COG1131	ABC-type multidrug transport system, ATPase component	293
643772645	115	31.25	5	114	7	116	2.0e-08	51.4	COG4679	Phage-related protein	116
643772649	113	32.32	1	97	9	107	3.0e-07	47.1	COG0640	DNA-binding transcriptional regulator, ArsR family	110
643772650	166	29.68	10	164	3	149	6.0e-17	80.5	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
643772653	538	36.8	3	533	1	486	3.0e-89	323	COG0286	Type I restriction-modification system, DNA methylase subunit	489
643772654	336	51.86	3	324	2	321	4.0e-87	315	COG3943	Uncharacterized conserved protein	329
643772655	409	21.38	24	401	1	388	9.0e-26	111	COG0732	Restriction endonuclease S subunit	391
643772656	1023	27.77	24	969	11	915	5.0e-123	436	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
643772658	191	33.58	21	149	2	130	5.0e-16	78	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
643772659	316	37.01	3	309	10	298	2.0e-61	229	COG2421	Acetamidase/formamidase	305
643772662	1003	34.83	18	288	2	279	2.0e-41	165	COG0515	Serine/threonine protein kinase	384
643772663	240	31.25	1	165	3	178	1.0e-27	116	COG1704	Uncharacterized conserved protein	185
643772664	736	34.11	49	328	8	286	4.0e-34	140	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
643772666	249	26.82	22	240	12	217	4.0e-11	62.2	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
643772668	195	32.43	9	193	2	182	1.0e-20	93.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643772671	553	34.3	49	552	2	474	2.0e-75	276	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
643772672	480	28.78	95	479	3	399	7.0e-49	188	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
643772673	137	36.72	14	137	12	138	4.0e-08	50.8	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
643772674	289	41.81	1	287	2	284	3.0e-72	265	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
643772675	443	22.76	141	421	17	267	2.0e-18	87.3	COG2339	Membrane proteinase PrsW, cleaves anti-sigma factor RsiW, M82 family	274
643772676	646	34.24	2	646	81	699	1.0e-125	444	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
643772678	445	34.28	8	428	1	403	1.0e-123	436	COG0137	Argininosuccinate synthase	403
643772680	237	25.78	7	230	16	221	3.0e-11	62.3	COG2801	Transposase InsO and inactivated derivatives	232
643772682	250	40.68	10	123	8	124	1.0e-20	93.4	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
643772684	311	36.96	1	303	1	296	2.0e-58	219	COG1893	Ketopantoate reductase	307
643772689	383	27.75	132	321	3	179	2.0e-17	83.9	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
643772691	377	32.08	86	336	1	238	6.0e-38	151	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
643772692	205	22.84	10	169	5	166	9.0e-07	47	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643772696	326	40.6	31	326	2	289	5.0e-74	271	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
643772697	499	24.82	65	479	17	435	9.0e-49	188	COG0612	Predicted Zn-dependent peptidase	438
643772698	465	25.49	59	451	15	426	3.0e-39	156	COG0612	Predicted Zn-dependent peptidase	438
643772700	487	22.12	42	487	12	409	2.0e-34	140	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643772701	207	58	7	104	8	106	8.0e-32	130	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
643772702	263	34.24	9	256	3	259	6.0e-43	167	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
643772703	260	61.02	1	251	1	254	2.0e-95	342	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
643772704	179	43.09	4	173	8	195	2.0e-48	185	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
643772705	237	41.92	1	227	2	230	5.0e-61	227	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
643772706	213	44.88	9	206	3	203	2.0e-51	195	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
643772707	816	47.12	21	435	10	418	2.0e-118	420	COG0141	Histidinol dehydrogenase	425
643772708	292	46.28	1	292	2	290	4.0e-76	278	COG0040	ATP phosphoribosyltransferase	290
643772709	165	30.5	24	164	12	126	1.0e-11	62.8	COG3794	Plastocyanin	128
643772712	169	51.01	10	157	9	154	7.0e-43	166	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
643772716	412	47.64	9	411	2	360	6.0e-127	447	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
643772722	233	34.84	17	233	1	220	4.0e-38	151	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
643772723	472	48.46	17	468	4	457	0.0e+00	488	COG0165	Argininosuccinate lyase	459
643772724	153	37.41	1	147	1	146	3.0e-32	131	COG1438	Arginine repressor	150
643772725	339	41.69	11	337	4	342	2.0e-77	283	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
643772726	260	43.39	1	234	4	242	2.0e-54	205	COG0548	Acetylglutamate kinase	265
643772727	411	47.63	15	411	3	398	2.0e-121	429	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
643772728	214	48.6	1	211	1	208	3.0e-58	218	COG2808	Predicted FMN-binding regulatory protein PaiB	209
643772729	528	18.6	16	525	26	450	1.0e-14	75.3	COG1524	Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily	450
643772732	107	33.64	1	107	1	110	1.0e-16	78	COG0607	Rhodanese-related sulfurtransferase	110
643772733	285	27.64	36	279	8	242	4.0e-29	121	COG1647	Esterase/lipase	243
643772734	281	34.71	28	269	37	277	1.0e-52	200	COG1398	Fatty-acid desaturase	289
643772735	92	41.89	4	77	5	78	2.0e-18	84.3	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
643772736	175	32.14	53	164	15	126	9.0e-12	63.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
643772737	171	43.03	3	163	25	189	4.0e-39	153	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
643772739	535	36.76	34	397	41	405	4.0e-73	269	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
643772741	334	41.54	11	332	7	324	8.0e-76	277	COG1171	Threonine dehydratase	347
643772742	274	21.68	49	267	2	215	1.0e-25	110	COG3340	Peptidase E	224
643772744	243	29.76	6	242	2	246	1.0e-20	93.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643772745	326	37.65	4	326	3	317	2.0e-53	203	COG4127	Predicted restriction endonuclease, Mrr-cat superfamily	318
643772746	1049	32.59	5	1018	3	962	0.0e+00	686	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
643772747	665	26.52	4	492	3	461	4.0e-56	213	COG2865	Predicted transcriptional regulator, contains HTH domain	467
643772748	445	18.39	5	431	1	391	8.0e-24	105	COG0732	Restriction endonuclease S subunit	391
643772749	519	37.45	19	516	7	489	4.0e-112	399	COG0286	Type I restriction-modification system, DNA methylase subunit	489
643772752	453	22.33	122	434	38	338	3.0e-37	149	COG3177	Fic family protein	348
643772757	359	32.3	28	341	3	304	5.0e-41	162	COG1397	ADP-ribosylglycohydrolase	314
643772760	367	36.14	1	362	2	363	7.0e-82	297	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
643772761	224	28.1	11	215	3	203	6.0e-11	61.1	COG0560	Phosphoserine phosphatase	212
643772762	466	33.76	9	466	7	456	2.0e-58	220	COG0277	FAD/FMN-containing dehydrogenase	459
643772763	534	47.54	1	305	3	306	1.0e-78	287	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
643772765	418	33.26	2	417	1	456	8.0e-71	261	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643772767	353	35.73	1	340	10	350	4.0e-64	239	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
643772770	455	49.21	17	452	2	441	0.0e+00	514	COG0174	Glutamine synthetase	443
643772771	207	48.22	7	202	3	194	4.0e-61	227	COG0605	Superoxide dismutase	204
643772772	222	31.46	20	196	13	187	3.0e-18	85.4	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
643772774	768	22.02	381	722	104	470	1.0e-20	95.9	COG5184	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	476
643772775	806	28.18	308	663	1	336	1.0e-35	145	COG0642	Signal transduction histidine kinase	336
643772777	141	25.35	1	137	10	149	8.0e-11	59.7	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
643772778	112	35.29	1	100	9	110	7.0e-09	52.5	COG0640	DNA-binding transcriptional regulator, ArsR family	110
643772779	136	41.35	5	135	1	132	1.0e-26	111	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
643772780	245	31.21	59	231	40	180	3.0e-12	65.8	COG3544	Uncharacterized conserved protein, DUF305 family	190
643772790	435	28.36	35	433	10	406	7.0e-57	215	COG4826	Serine protease inhibitor	410
643772792	138	53.91	4	131	2	129	3.0e-40	157	COG3607	Predicted lactoylglutathione lyase	133
643772793	322	35.56	2	181	19	177	2.0e-26	113	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643772794	439	22.96	1	189	1	178	1.0e-08	55	COG1988	Membrane-bound metal-dependent hydrolase YbcI, DUF457 family	190
643772795	94	35.79	1	92	3	97	8.0e-14	68.5	COG1359	Quinol monooxygenase YgiN	100
643772796	532	29.04	31	385	15	362	2.0e-39	157	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643772797	313	35.29	127	293	1	168	2.0e-33	136	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
643772800	175	45	2	159	8	164	1.0e-40	159	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
643772801	74	44.64	12	67	1	55	1.0e-08	51.4	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
643772802	395	39.72	56	395	54	395	2.0e-83	303	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
643772803	483	35.97	2	469	17	466	8.0e-84	304	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
643772805	399	28.96	64	387	3	304	5.0e-49	188	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
643772806	633	32.79	15	296	1	302	2.0e-49	191	COG0515	Serine/threonine protein kinase	384
643772809	380	49.87	1	379	11	391	3.0e-113	401	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
643772812	740	48.89	21	738	13	722	0.0e+00	755	COG3968	Glutamine synthetase type III	724
643772815	259	36.12	1	257	1	251	3.0e-38	152	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643772816	358	43.5	8	357	1	349	2.0e-89	322	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
643772818	289	34.83	1	286	4	292	1.0e-64	239	COG1131	ABC-type multidrug transport system, ATPase component	293
643772819	309	33.78	11	299	1	298	3.0e-51	195	COG1893	Ketopantoate reductase	307
643772820	412	23.32	1	399	1	406	1.0e-39	157	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
643772821	173	28.05	48	129	20	98	1.0e-05	43.4	COG2944	DNA-binding transcriptional regulator YiaG, XRE-type HTH domain	104
643772823	691	27.23	32	686	2	616	3.0e-74	273	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
643772824	257	37.5	19	254	5	257	2.0e-29	122	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
643772826	296	31.35	45	214	42	221	3.0e-20	92.3	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
643772827	279	47.04	7	273	6	275	2.0e-83	302	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
643772830	308	34.77	22	298	4	274	1.0e-49	190	COG3327	DNA-binding transcriptional regulator PaaX (phenylacetic acid degradation)	291
643772831	341	48.87	31	295	1	264	4.0e-90	324	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
643772832	93	57.43	3	93	9	109	8.0e-27	111	COG3460	1,2-phenylacetyl-CoA epoxidase, PaaB subunit	117
643772833	250	37.05	3	250	19	265	2.0e-52	198	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
643772834	195	36.89	26	127	9	108	8.0e-20	90.3	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
643772835	359	25.59	1	296	2	266	6.0e-41	161	COG1018	Ferredoxin-NADP reductase	266
643772836	315	33.88	4	308	3	291	2.0e-62	232	COG1131	ABC-type multidrug transport system, ATPase component	293
643772838	308	33.33	6	308	2	293	8.0e-56	210	COG1131	ABC-type multidrug transport system, ATPase component	293
643772840	216	32.29	23	207	7	194	2.0e-21	95.8	COG0778	Nitroreductase	207
643772841	158	36.72	27	153	1	126	2.0e-12	65.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
643772844	460	19.59	4	386	3	381	2.0e-06	47.1	COG0475	Kef-type K+ transport system, membrane component KefB	397
643772845	427	22.52	16	416	7	396	5.0e-14	72.6	COG0475	Kef-type K+ transport system, membrane component KefB	397
643772847	320	26.58	27	313	7	268	4.0e-14	72.3	COG3769	Predicted mannosyl-3-phosphoglycerate phosphatase, HAD superfamily	274
643772848	390	48.94	18	382	14	390	7.0e-90	324	COG3004	Na+/H+ antiporter NhaA	390
643772849	515	32.68	30	377	23	370	1.0e-56	214	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
643772853	316	43.08	125	313	5	194	7.0e-40	157	COG1045	Serine acetyltransferase	194
643772854	305	54.21	5	298	4	299	6.0e-101	361	COG0031	Cysteine synthase	300
643772855	404	32.27	30	372	76	415	4.0e-54	205	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
643772857	131	42.06	9	115	7	112	1.0e-23	101	COG1733	DNA-binding transcriptional regulator, HxlR family	120
643772858	250	42.11	11	250	6	251	1.0e-37	150	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643772861	239	41.08	1	237	4	244	2.0e-60	226	COG1131	ABC-type multidrug transport system, ATPase component	293
643772863	417	29.73	10	409	3	402	4.0e-66	245	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
643772864	289	29.96	12	254	1	240	3.0e-38	152	COG1360	Flagellar motor protein MotB	244
643772865	285	34.86	1	284	3	265	3.0e-55	208	COG1291	Flagellar motor component MotA	266
643772867	100	44.62	1	65	1	65	2.0e-14	70.3	COG1551	sRNA-binding carbon storage regulator CsrA	73
643772868	482	25.17	1	446	2	446	5.0e-53	202	COG1256	Flagellar hook-associated protein FlgK	552
643772871	351	33.15	11	350	7	364	7.0e-51	194	COG1706	Flagellar basal body P-ring protein FlgI	365
643772872	235	28.92	77	233	67	230	3.0e-16	78.8	COG2063	Flagellar basal body L-ring protein FlgH	230
643772874	262	49.25	1	262	1	265	5.0e-77	281	COG4786	Flagellar basal body rod protein FlgG	265
643772875	234	28.79	7	231	2	265	1.0e-35	143	COG4786	Flagellar basal body rod protein FlgG	265
643772876	360	26.78	25	310	34	316	5.0e-31	128	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
643772877	352	42.27	14	349	3	334	3.0e-52	198	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
643772878	260	38.62	14	246	2	246	2.0e-57	216	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
643772880	251	37.8	3	246	12	247	2.0e-44	173	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
643772881	288	28.69	39	269	8	230	2.0e-12	66.8	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
643772883	695	50.72	1	689	2	692	0.0e+00	742	COG1298	Flagellar biosynthesis pathway, component FlhA	696
643772884	366	41.34	2	359	1	356	7.0e-91	327	COG1377	Flagellar biosynthesis protein FlhB	363
643772885	295	34.96	16	241	10	235	3.0e-31	129	COG1684	Flagellar biosynthesis protein FliR	258
643772886	89	47.19	1	89	1	89	2.0e-11	60.5	COG1987	Flagellar biosynthesis protein FliQ	89
643772888	255	56.02	40	255	33	248	3.0e-62	232	COG1338	Flagellar biosynthetic protein FliP	248
643772889	141	45.36	32	128	40	136	3.0e-19	87.4	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
643772890	331	30.96	3	319	2	319	2.0e-45	176	COG1868	Flagellar motor switch protein FliM	332
643772891	189	22.63	1	189	2	159	6.0e-09	54.1	COG1580	Flagellar basal body-associated protein FliL	159
643772892	506	33.98	1	506	1	423	7.0e-73	268	COG1749	Flagellar hook protein FlgE	423
643772893	267	28.57	37	265	15	221	3.0e-19	89.3	COG1843	Flagellar hook assembly protein FlgD	222
643772896	167	23.81	1	147	2	148	6.0e-09	53.8	COG2882	Flagellar biosynthesis chaperone FliJ	148
643772897	457	59.23	9	447	1	439	0.0e+00	582	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
643772898	227	23.74	14	227	14	229	2.0e-13	69.6	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
643772899	348	45.32	17	347	9	339	2.0e-73	269	COG1536	Flagellar motor switch protein FliG	339
643772900	540	27.82	1	538	8	542	9.0e-70	258	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
643772901	106	33.33	31	105	30	104	1.0e-13	68.4	COG1677	Flagellar hook-basal body complex protein FliE	105
643772903	183	33.7	3	183	2	135	4.0e-32	131	COG1558	Flagellar basal body rod protein FlgC	137
643772905	526	45.83	38	517	2	452	0.0e+00	470	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643772906	302	21.01	1	302	1	357	2.0e-16	79.7	COG1344	Flagellin and related hook-associated protein FlgL	360
643772907	158	29.63	11	143	4	137	6.0e-17	80.3	COG1699	Flagellar assembly factor FliW	146
643772910	379	44.53	14	379	1	373	9.0e-104	370	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
643772911	354	26.63	9	345	4	341	3.0e-40	159	COG0673	Predicted dehydrogenase	342
643772915	489	28.29	9	489	25	525	2.0e-53	203	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
643772916	245	44.44	1	244	3	251	3.0e-40	158	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643772918	205	23.31	26	179	10	170	7.0e-06	44.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
643772922	684	21.7	303	680	87	481	4.0e-21	97	COG1345	Flagellar capping protein FliD	483
643772923	132	26.56	1	128	1	128	4.0e-15	73.8	COG1516	Flagellin-specific chaperone FliS	132
643772930	179	40.82	31	176	19	165	2.0e-33	135	COG0835	Chemotaxis signal transduction protein	165
643772931	279	40.52	20	279	3	265	9.0e-71	260	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
643772932	170	34.39	6	162	4	155	2.0e-26	112	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
643772935	348	48.13	1	343	1	347	2.0e-95	343	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
643772938	243	35.5	12	236	44	274	2.0e-46	179	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
643772939	468	45.64	172	467	1	295	1.0e-81	297	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
643772941	374	24.65	36	318	8	268	2.0e-11	63.7	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
643772942	340	23.79	32	280	3	260	8.0e-09	55	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643772943	256	26.78	15	248	6	238	1.0e-23	103	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
643772944	154	33.33	4	141	5	139	1.0e-15	76.1	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
643772946	254	44.86	10	249	4	246	1.0e-73	269	COG1131	ABC-type multidrug transport system, ATPase component	293
643772947	362	34.78	154	359	75	281	3.0e-22	99.6	COG0842	ABC-type multidrug transport system, permease component	286
643772948	327	44.65	1	325	1	315	1.0e-91	329	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
643772949	301	41.52	50	272	58	266	6.0e-55	207	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
643772950	219	44.5	7	215	2	209	2.0e-39	155	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
643772952	406	31.32	22	399	6	372	5.0e-61	228	COG0116	23S rRNA G2445 N2-methylase RlmL	381
643772954	189	33.15	5	176	9	182	2.0e-23	101	COG3172	Nicotinamide riboside kinase	187
643772955	208	26.7	17	203	27	217	1.0e-18	86.5	COG3201	Nicotinamide riboside transporter PnuC	222
643772956	706	17.62	11	706	5	768	4.0e-15	77.3	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643772957	329	30.37	17	325	9	331	1.0e-39	157	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
643772958	423	34.62	114	423	35	331	2.0e-40	160	COG0642	Signal transduction histidine kinase	336
643772959	923	48.56	9	904	14	901	0.0e+00	1055	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
643772960	873	29.81	31	234	11	194	2.0e-12	68.6	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
643772962	145	39.68	11	73	6	68	1.0e-06	45.6	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
643772964	476	45.34	20	422	4	404	1.0e-113	403	COG1252	NADH dehydrogenase, FAD-containing subunit	405
643772965	672	28.14	251	536	48	334	5.0e-32	132	COG0642	Signal transduction histidine kinase	336
643772966	200	36.13	6	196	4	192	5.0e-26	110	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
643772967	481	26.03	44	475	17	408	2.0e-42	166	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643772968	544	26.17	49	517	1	442	6.0e-65	242	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
643772969	462	25.22	18	453	3	449	4.0e-52	199	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
643772972	359	46.2	27	359	1	339	6.0e-90	324	COG0309	Hydrogenase maturation factor	339
643772973	371	49.18	1	361	1	363	3.0e-125	441	COG0409	Hydrogenase maturation factor	364
643772974	101	44.3	1	78	1	77	2.0e-16	77.2	COG0298	Hydrogenase maturation factor	82
643772976	296	40	101	173	10	84	1.0e-16	80.8	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
643772980	164	29.03	6	155	3	153	4.0e-21	94.2	COG0680	Ni,Fe-hydrogenase maturation factor	160
643772981	534	28.49	7	530	6	545	2.0e-111	396	COG0374	Ni,Fe-hydrogenase I large subunit	545
643772982	323	33.44	4	319	51	355	1.0e-82	300	COG1740	Ni,Fe-hydrogenase I small subunit	355
643772983	213	45.67	6	207	2	209	1.0e-46	179	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643772985	237	38.24	20	218	2	196	1.0e-48	186	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
643772986	141	39.47	1	114	1	113	3.0e-23	101	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
643772987	221	30.41	77	220	3	147	5.0e-06	45	COG2427	Uncharacterized conserved protein YjgD, DUF1641 family	148
643772988	859	41.9	21	838	3	746	0.0e+00	729	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
643772992	486	35.88	5	486	14	514	3.0e-111	395	COG1640	4-alpha-glucanotransferase	520
643772994	662	43.33	76	643	4	564	0.0e+00	461	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
643772995	410	21.32	1	390	3	381	9.0e-18	84.9	COG2814	Predicted arabinose efflux permease, MFS family	394
643772996	292	42.71	1	291	5	299	3.0e-56	212	COG1079	ABC-type uncharacterized transport system, permease component	304
643772997	361	41.32	6	333	12	339	6.0e-57	215	COG4603	ABC-type uncharacterized transport system, permease component	356
643772998	532	53.46	14	529	1	501	0.0e+00	599	COG3845	ABC-type uncharacterized transport system, ATPase component	501
643772999	348	40.8	1	342	1	335	4.0e-70	258	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
643773003	512	49.9	6	512	2	510	0.0e+00	560	COG0029	Aspartate oxidase	518
643773004	339	51.58	12	325	20	324	6.0e-109	387	COG0379	Quinolinate synthase	324
643773005	319	52.52	41	316	1	277	3.0e-87	315	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
643773007	433	20.95	81	371	8	238	9.0e-24	105	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
643773008	231	43.69	6	227	1	209	2.0e-47	182	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643773009	620	35.66	31	413	4	383	3.0e-66	246	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643773012	131	44.72	6	126	1	123	8.0e-19	86	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
643773013	466	29.89	20	458	14	406	4.0e-59	222	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643773014	744	31.5	356	657	82	408	5.0e-32	133	COG0840	Methyl-accepting chemotaxis protein	408
643773015	737	52.66	365	737	49	418	7.0e-125	441	COG1158	Transcription termination factor Rho	422
643773017	132	23.58	19	124	12	116	8.0e-14	69.7	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
643773021	804	41.48	106	669	57	594	0.0e+00	464	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
643773022	427	33.73	1	415	7	408	3.0e-60	226	COG4102	Uncharacterized conserved protein, DUF1501 family	418
643773023	597	34.93	28	493	2	440	1.0e-68	254	COG5267	Uncharacterized conserved protein, DUF1800 family	496
643773026	698	40.2	1	691	2	693	0.0e+00	656	COG0480	Translation elongation factor EF-G, a GTPase	697
643773027	255	36.16	30	246	23	245	1.0e-35	143	COG1351	Thymidylate synthase ThyX	273
643773028	162	38.46	44	159	12	126	7.0e-09	53.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
643773029	576	31.98	45	527	13	458	2.0e-55	210	COG0277	FAD/FMN-containing dehydrogenase	459
643773030	352	26.67	15	329	8	286	2.0e-25	110	COG1562	Phytoene/squalene synthetase	288
643773031	237	25.78	7	230	16	221	3.0e-11	62.3	COG2801	Transposase InsO and inactivated derivatives	232
643773037	211	36.94	8	162	4	150	3.0e-25	108	COG0328	Ribonuclease HI	154
643773039	384	34.01	8	378	14	402	2.0e-48	186	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643773040	326	32.01	13	319	2	329	3.0e-46	178	COG2605	Predicted kinase related to galactokinase and mevalonate kinase	333
643773042	377	40.31	1	365	4	379	2.0e-78	286	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
643773043	186	39.33	13	184	1	178	6.0e-29	120	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643773045	470	49.02	5	460	1	454	0.0e+00	501	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
643773048	261	24.65	8	259	1	282	1.0e-14	73.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643773049	409	51.82	1	409	2	404	2.0e-106	379	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
643773050	345	38.35	1	344	1	325	2.0e-66	246	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
643773053	837	56.51	8	817	6	804	0.0e+00	978	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
643773054	491	33.12	28	490	13	431	4.0e-54	206	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
643773055	203	35.9	1	193	3	188	7.0e-30	123	COG0406	Broad specificity phosphatase PhoE	208
643773056	268	35.71	13	262	2	243	4.0e-30	125	COG0368	Cobalamin synthase	246
643773057	574	38.4	204	564	5	337	2.0e-62	234	COG2038	NaMN:DMB phosphoribosyltransferase	347
643773058	179	49.71	8	178	27	197	5.0e-50	190	COG2109	ATP:corrinoid adenosyltransferase	198
643773059	240	42.08	59	239	20	197	5.0e-43	167	COG2109	ATP:corrinoid adenosyltransferase	198
643773060	360	34.16	3	352	1	355	8.0e-54	204	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
643773061	330	40.88	10	319	8	306	4.0e-57	215	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
643773063	650	24.65	34	643	25	607	4.0e-36	146	COG4206	Outer membrane cobalamin receptor protein	608
643773064	271	44.4	7	262	1	257	1.0e-72	266	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
643773065	335	43.5	6	333	4	333	2.0e-56	213	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
643773066	321	31.65	13	296	19	314	6.0e-40	158	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
643773067	531	50	25	526	4	486	0.0e+00	543	COG1492	Cobyric acid synthase	486
643773068	193	48.62	8	188	4	175	3.0e-40	158	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
643773069	154	44.03	19	151	5	135	1.0e-29	122	COG1832	Predicted CoA-binding protein	140
643773070	381	30.83	1	379	2	379	6.0e-55	208	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
643773071	571	26.01	129	547	1	398	4.0e-26	113	COG0840	Methyl-accepting chemotaxis protein	408
643773072	410	28.65	70	402	29	366	2.0e-34	140	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
643773073	429	36.9	13	262	2	245	2.0e-51	196	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
643773074	626	50.87	20	591	6	566	0.0e+00	559	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
643773075	230	38.43	1	229	2	206	1.0e-36	146	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
643773077	307	23.48	82	303	52	280	2.0e-24	106	COG3336	Cytochrome c oxidase assembly factor CtaG	299
643773081	401	32.4	10	401	5	371	3.0e-62	232	COG4299	Predicted acyltransferase	371
643773082	545	31.24	91	542	20	466	5.0e-65	242	COG2027	D-alanyl-D-alanine carboxypeptidase	470
643773085	525	64.13	55	514	4	463	0.0e+00	690	COG1027	Aspartate ammonia-lyase	471
643773086	349	34.04	59	337	31	300	1.0e-47	183	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
643773087	811	47.09	8	811	3	814	0.0e+00	876	COG0495	Leucyl-tRNA synthetase	814
643773090	420	33.42	10	375	3	368	1.0e-30	127	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643773091	1037	40.51	2	1013	1	1009	0.0e+00	955	COG0841	Multidrug efflux pump subunit AcrB	1009
643773092	642	51.26	8	641	2	626	0.0e+00	743	COG3158	K+ transporter	627
643773093	438	26.09	1	435	18	443	7.0e-26	112	COG1538	Outer membrane protein TolC	457
643773096	187	38.86	13	180	1	175	2.0e-24	105	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643773097	208	51.34	7	193	31	212	5.0e-50	190	COG2316	Predicted hydrolase, HD superfamily	212
643773099	345	39.13	1	342	10	338	3.0e-58	219	COG1566	Multidrug resistance efflux pump	352
643773100	478	27.9	31	472	15	443	2.0e-22	100	COG1538	Outer membrane protein TolC	457
643773101	210	25.15	9	175	4	169	5.0e-11	61.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643773103	156	44.81	4	155	1	144	9.0e-40	156	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
643773104	246	52.22	44	246	9	210	1.0e-72	266	COG0177	Endonuclease III	211
643773105	592	34.71	347	584	1	235	2.0e-43	170	COG1387	Histidinol phosphatase or related hydrolase of the PHP family	237
643773107	282	27.86	7	277	10	280	1.0e-22	100	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643773109	359	37.6	3	355	1	351	1.0e-78	286	COG1363	Putative aminopeptidase FrvX	355
643773111	300	22.82	2	290	54	319	2.0e-18	86.9	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
643773112	559	39.52	24	556	3	535	1.0e-125	443	COG1574	Predicted amidohydrolase YtcJ	535
643773113	160	49.68	7	159	31	183	3.0e-34	138	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
643773115	465	18.05	142	465	1	309	3.0e-07	50	COG3021	Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily	309
643773120	534	29.34	1	532	6	531	3.0e-69	256	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
643773122	215	22.86	72	210	35	174	3.0e-08	51.8	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
643773123	322	21.05	2	296	82	364	8.0e-13	68.1	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643773124	385	45.57	12	385	5	388	9.0e-86	310	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643773125	422	19.74	35	404	2	379	2.0e-11	63.8	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
643773126	627	32.48	1	621	1	542	1.0e-89	324	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
643773127	629	38.74	17	300	9	310	8.0e-74	271	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
643773128	1245	56.9	347	1214	1	842	0.0e+00	1105	COG1410	Methionine synthase I, cobalamin-binding domain	842
643773131	401	20.28	53	401	30	378	1.0e-18	87.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643773132	360	26.91	4	360	3	377	7.0e-26	111	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643773134	479	19.7	112	435	78	398	1.0e-09	58.2	COG3307	O-antigen ligase	424
643773135	361	29.69	1	361	3	380	2.0e-34	140	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643773138	251	26.6	27	203	3	187	1.0e-19	90.1	COG3306	Glycosyltransferase involved in LPS biosynthesis, GR25 family	255
643773139	488	22.91	12	469	7	473	9.0e-18	85.2	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
643773140	451	48.98	43	433	3	384	3.0e-122	432	COG0372	Citrate synthase	390
643773141	468	30.3	5	386	3	393	1.0e-53	203	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
643773142	79	32.05	1	78	1	78	7.0e-06	42.2	COG0236	Acyl carrier protein	80
643773144	508	28.25	1	507	8	527	3.0e-64	240	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
643773146	282	24.9	27	282	85	334	1.0e-22	100	COG0642	Signal transduction histidine kinase	336
643773147	496	43.31	22	490	6	460	1.0e-126	447	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643773148	816	25.4	567	801	23	265	1.0e-28	122	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
643773152	458	49.54	12	439	1	433	0.0e+00	507	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
643773153	353	36.83	1	352	4	371	1.0e-77	283	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
643773154	260	44.13	46	258	34	224	2.0e-55	209	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
643773158	344	52.08	1	336	3	313	5.0e-118	417	COG1088	dTDP-D-glucose 4,6-dehydratase	340
643773160	705	16.69	17	703	26	765	3.0e-19	90.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643773162	497	27.7	38	478	5	415	1.0e-57	217	COG1239	Mg-chelatase subunit ChlI	423
643773163	398	22.06	15	396	6	391	1.0e-15	78.1	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
643773165	357	27.97	49	357	21	301	2.0e-33	137	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
643773167	456	28.16	32	445	8	387	1.0e-59	224	COG0247	Fe-S oxidoreductase	388
643773168	400	23.04	4	386	31	451	9.0e-29	121	COG0277	FAD/FMN-containing dehydrogenase	459
643773169	470	40	6	455	1	457	5.0e-84	305	COG0277	FAD/FMN-containing dehydrogenase	459
643773171	302	40.81	21	290	64	331	9.0e-55	207	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
643773172	376	41.16	18	376	12	359	2.0e-95	342	COG0337	3-dehydroquinate synthetase	360
643773173	181	58.56	1	181	5	178	8.0e-58	216	COG2096	Cob(I)alamin adenosyltransferase	184
643773174	344	32.19	8	327	5	305	2.0e-51	196	COG0492	Thioredoxin reductase	305
643773175	306	49.68	1	306	1	316	5.0e-90	324	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
643773176	519	32.68	37	504	48	540	2.0e-73	270	COG0747	ABC-type transport system, periplasmic component	556
643773177	768	21.89	54	691	174	745	2.0e-53	204	COG4775	Outer membrane protein assembly factor BamA	766
643773180	245	31.54	85	231	45	191	2.0e-16	79.6	COG0791	Cell wall-associated hydrolase, NlpC family	197
643773182	320	28.82	22	307	10	291	4.0e-10	59.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
643773183	229	25.34	1	219	4	212	5.0e-16	77.9	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
643773185	711	42.17	13	709	3	652	0.0e+00	587	COG0370	Fe2+ transport system protein B	653
643773186	98	36.99	27	96	3	75	1.0e-05	41.3	COG1918	Fe2+ transport system protein FeoA	75
643773187	268	27.9	6	266	12	275	7.0e-33	134	COG0682	Prolipoprotein diacylglyceryltransferase	287
643773188	357	47.43	1	347	1	334	1.0e-105	376	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
643773189	183	27.04	35	180	4	154	1.0e-14	73	COG1225	Peroxiredoxin	157
643773190	221	54.17	1	216	2	216	7.0e-76	276	COG0036	Pentose-5-phosphate-3-epimerase	220
643773192	428	35.18	76	425	1	355	2.0e-69	256	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
643773193	324	48.73	1	316	2	307	1.0e-94	339	COG0223	Methionyl-tRNA formyltransferase	307
643773194	196	47.85	1	156	1	163	4.0e-47	181	COG0242	Peptide deformylase	168
643773195	117	36.08	22	117	10	96	2.0e-14	71	COG1862	Preprotein translocase subunit YajC	97
643773196	384	49.73	6	377	1	362	3.0e-128	452	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
643773197	353	49.56	12	353	2	343	2.0e-124	439	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
643773198	342	63.41	5	332	3	330	0.0e+00	481	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
643773200	238	40.18	10	224	2	215	2.0e-55	209	COG1136	ABC-type lipoprotein export system, ATPase component	226
643773202	197	38.81	1	194	1	200	2.0e-42	165	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
643773203	181	47.65	8	156	1	148	7.0e-46	176	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
643773204	247	53.11	1	241	1	241	1.0e-85	309	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
643773208	639	39.93	17	612	2	565	3.0e-123	436	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
643773209	371	16.32	1	358	3	381	4.0e-08	53.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643773210	279	56.27	1	278	12	289	1.0e-76	280	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
643773211	386	30.34	3	386	1	403	2.0e-55	209	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
643773212	428	46.82	7	427	5	400	2.0e-111	395	COG0162	Tyrosyl-tRNA synthetase	401
643773213	717	39.54	10	694	9	661	0.0e+00	537	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
643773214	474	34.19	26	443	12	413	7.0e-56	211	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
643773215	195	33.09	12	150	1	131	6.0e-17	80.8	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
643773218	472	48.72	1	467	4	456	0.0e+00	469	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643773222	529	36.16	1	518	7	526	1.0e-95	344	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
643773224	194	54.17	3	194	4	193	3.0e-56	211	COG2094	3-methyladenine DNA glycosylase Mpg	200
643773225	398	45.62	8	392	7	388	3.0e-106	378	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
643773226	341	33.52	1	341	1	349	7.0e-66	244	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
643773230	264	33.33	1	263	1	273	6.0e-59	220	COG0266	Formamidopyrimidine-DNA glycosylase	273
643773231	420	22.1	6	366	19	381	6.0e-24	105	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643773232	390	42.05	8	387	2	391	3.0e-86	312	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
643773233	275	20.52	9	233	5	230	2.0e-12	66.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
643773234	350	33.43	4	339	1	341	3.0e-73	269	COG1559	Cell division protein YceG, involved in septum cleavage	342
643773235	168	43.61	6	138	2	134	5.0e-27	114	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
643773236	417	66.03	1	416	4	420	0.0e+00	606	COG1158	Transcription termination factor Rho	422
643773238	281	25.21	96	214	3	121	1.0e-07	51	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643773242	283	35.31	2	278	1	283	3.0e-37	148	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
643773244	510	31.03	15	285	1	277	1.0e-40	161	COG0515	Serine/threonine protein kinase	384
643773248	442	26.24	149	405	20	265	1.0e-22	101	COG4242	Cyanophycinase and related exopeptidases	293
643773250	164	39.13	3	161	22	173	3.0e-31	127	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
643773252	366	32.4	13	360	12	353	2.0e-53	203	COG1858	Cytochrome c peroxidase	364
643773253	387	31.2	1	381	1	381	2.0e-40	160	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643773254	402	25.83	12	388	2	377	1.0e-35	144	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643773255	250	22.83	7	223	2	197	3.0e-16	79.2	COG3233	Predicted deacetylase	233
643773256	411	24.36	31	411	3	381	8.0e-30	125	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643773261	413	40.52	32	412	29	409	6.0e-101	361	COG3876	Uncharacterized conserved protein YbbC, DUF1343 family	409
643773263	401	34.23	7	376	26	381	2.0e-71	262	COG3876	Uncharacterized conserved protein YbbC, DUF1343 family	409
643773264	825	23.1	156	766	147	757	1.0e-45	178	COG0417	DNA polymerase elongation subunit (family B)	792
643773266	611	34.52	19	320	4	310	2.0e-52	200	COG1290	Cytochrome b subunit of the bc complex	381
643773267	178	20.35	1	164	2	165	2.0e-08	52.5	COG0723	Rieske Fe-S protein	177
643773269	254	43.56	17	241	2	210	3.0e-52	198	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
643773270	242	28.1	35	154	5	124	5.0e-12	65	COG1846	DNA-binding transcriptional regulator, MarR family	126
643773272	111	36.36	5	102	8	106	8.0e-12	62.5	COG0640	DNA-binding transcriptional regulator, ArsR family	110
643773274	251	25.69	1	218	2	164	8.0e-13	67.7	COG0622	Predicted phosphodiesterase	172
643773275	383	52.02	15	360	5	341	5.0e-91	328	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
643773285	295	39.42	13	283	56	329	2.0e-62	232	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
643773286	285	45.27	1	242	8	250	8.0e-78	283	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
643773287	162	18.54	8	150	1	151	1.0e-07	49.6	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
643773288	295	23.53	143	244	11	112	1.0e-06	47.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643773289	523	65.44	6	523	2	502	0.0e+00	765	COG0056	FoF1-type ATP synthase, alpha subunit	504
643773290	290	43.71	5	288	1	286	4.0e-75	275	COG0224	FoF1-type ATP synthase, gamma subunit	287
643773291	476	70	9	476	2	467	0.0e+00	771	COG0055	FoF1-type ATP synthase, beta subunit	468
643773300	436	29.53	35	431	21	415	2.0e-54	207	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
643773301	263	24.39	10	243	6	243	8.0e-22	97.6	COG1651	Protein-disulfide isomerase	244
643773302	285	25.62	11	283	4	262	8.0e-27	114	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
643773304	205	45.74	14	201	1	185	1.0e-47	182	COG1704	Uncharacterized conserved protein	185
643773309	515	40.65	1	507	4	543	0.0e+00	495	COG0143	Methionyl-tRNA synthetase	558
643773310	442	36.07	31	272	30	265	4.0e-44	172	COG1774	Cell fate regulator YaaT, PSP1 superfamily (controls sporulation, competence, biofilm development)	265
643773311	322	60.31	3	322	1	317	7.0e-122	430	COG0825	Acetyl-CoA carboxylase alpha subunit	317
643773312	1165	46.34	1	1161	2	1139	0.0e+00	1194	COG0587	DNA polymerase III, alpha subunit	1139
643773313	366	31.02	21	345	18	346	6.0e-38	151	COG4324	Predicted aminopeptidase	376
643773314	950	27.46	39	482	5	433	6.0e-51	196	COG0612	Predicted Zn-dependent peptidase	438
643773315	702	36.17	27	657	3	637	8.0e-117	414	COG0210	Superfamily I DNA or RNA helicase	655
643773319	276	38.43	20	248	4	216	2.0e-55	209	COG0321	Lipoate-protein ligase B	221
643773320	466	46.17	1	455	2	453	0.0e+00	465	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
643773323	441	43.92	1	440	1	402	7.0e-94	337	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
643773324	326	54.97	4	324	2	323	0.0e+00	466	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
643773325	347	50	31	346	30	346	3.0e-103	368	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
643773326	337	58.82	46	334	15	303	7.0e-126	443	COG0320	Lipoate synthase	306
643773328	698	22.54	1	243	4	227	6.0e-12	66.7	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
643773331	509	38.57	1	508	4	498	2.0e-105	376	COG3104	Dipeptide/tripeptide permease	498
643773333	340	58.31	9	326	1	316	5.0e-125	440	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
643773334	320	45.35	22	278	29	284	2.0e-56	212	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
643773335	329	38.56	4	320	3	316	4.0e-67	248	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
643773336	562	22.82	1	543	2	554	8.0e-56	211	COG0747	ABC-type transport system, periplasmic component	556
643773337	277	27.24	34	274	13	234	9.0e-22	97.7	COG0095	Lipoate-protein ligase A	248
643773338	965	56.6	16	452	5	450	0.0e+00	595	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
643773338	965	59.67	464	934	17	496	0.0e+00	695	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
643773339	127	48.84	1	127	2	129	1.0e-36	145	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
643773340	215	43	1	200	2	198	6.0e-43	167	COG0237	Dephospho-CoA kinase	201
643773341	271	29.17	119	238	2	121	1.0e-08	53.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643773343	203	47.74	10	202	4	201	9.0e-61	226	COG1435	Thymidine kinase	201
643773344	777	15.24	139	552	86	513	5.0e-10	60.2	COG0513	Superfamily II DNA and RNA helicase	513
643773345	396	42.64	11	394	3	389	3.0e-88	319	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
643773349	397	20.66	1	268	1	295	9.0e-21	94.9	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
643773350	800	22.72	1	791	1	901	2.0e-39	158	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
643773354	137	30.66	6	137	5	127	3.0e-18	84.6	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
643773355	222	61.54	34	215	10	191	2.0e-75	275	COG0302	GTP cyclohydrolase I	195
643773356	253	35.68	17	253	4	242	5.0e-45	174	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
643773361	255	31.25	1	254	1	254	1.0e-40	159	COG1192	Cellulose biosynthesis protein BcsQ	259
643773363	179	28.14	15	177	4	170	1.0e-17	82.7	COG2236	Hypoxanthine phosphoribosyltransferase	192
643773365	689	50.07	8	676	3	666	0.0e+00	825	COG0272	NAD-dependent DNA ligase	667
643773368	444	47.24	1	434	2	435	3.0e-130	458	COG0213	Thymidine phosphorylase	435
643773370	692	34.29	1	377	1	381	6.0e-46	179	COG0475	Kef-type K+ transport system, membrane component KefB	397
643773372	284	29.07	14	278	8	320	1.0e-31	130	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
643773375	129	30.77	4	120	1	117	3.0e-18	84.2	COG3682	Predicted transcriptional regulator	123
643773376	660	37.26	411	658	39	301	5.0e-20	93.1	COG1413	HEAT repeat	335
643773380	340	31.15	219	339	1	121	3.0e-13	69.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643773381	117	33.7	1	92	4	95	3.0e-06	44	COG0640	DNA-binding transcriptional regulator, ArsR family	110
643773382	319	19.35	1	155	1	148	2.0e-13	69.7	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
643773385	499	27.91	2	376	1	379	6.0e-51	195	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
643773386	582	36.5	254	554	83	408	2.0e-47	184	COG0840	Methyl-accepting chemotaxis protein	408
643773388	658	63.52	13	658	3	635	0.0e+00	979	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
643773390	376	35.97	2	367	3	352	7.0e-66	244	COG1195	Recombinational DNA repair ATPase RecF	363
643773391	259	50.39	1	256	2	257	1.0e-60	226	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
643773392	344	50.15	8	336	1	336	5.0e-101	361	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
643773393	504	55.56	4	494	7	499	0.0e+00	636	COG0554	Glycerol kinase	499
643773394	151	32.24	2	151	6	152	1.0e-20	92.6	COG2332	Cytochrome c-type biogenesis protein CcmE	153
643773395	679	33.44	1	649	2	636	6.0e-111	395	COG1138	Cytochrome c biogenesis factor	648
643773401	251	40.87	1	250	4	255	6.0e-68	250	COG1131	ABC-type multidrug transport system, ATPase component	293
643773402	120	44.23	16	119	1	103	2.0e-25	108	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
643773403	962	62.46	4	962	3	934	0.0e+00	1452	COG0178	Excinuclease UvrABC ATPase subunit	935
643773404	222	33.03	1	214	35	249	2.0e-35	142	COG1760	L-serine deaminase	262
643773405	294	40.77	16	275	11	262	7.0e-51	194	COG1760	L-serine deaminase	262
643773408	284	39.82	1	226	1	222	2.0e-22	99.6	COG1842	Phage shock protein A	225
643773410	473	44.54	3	473	1	464	0.0e+00	524	COG0215	Cysteinyl-tRNA synthetase	464
643773415	905	26.18	80	385	2	294	5.0e-37	150	COG0515	Serine/threonine protein kinase	384
643773416	844	44.83	665	838	2	175	4.0e-37	150	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
643773419	206	46.94	9	204	6	201	4.0e-51	194	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
643773420	177	47.33	24	173	12	159	1.0e-35	142	COG4420	Uncharacterized membrane protein	191
643773421	461	27.09	38	432	46	432	4.0e-24	106	COG1538	Outer membrane protein TolC	457
643773422	404	28.64	18	404	1	419	1.0e-32	134	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
643773423	252	48.89	8	230	1	224	3.0e-77	281	COG1136	ABC-type lipoprotein export system, ATPase component	226
643773424	451	34	3	299	13	310	1.0e-21	98.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643773426	289	32.51	7	287	2	243	4.0e-38	151	COG3279	DNA-binding response regulator, LytR/AlgR family	244
643773427	50	66	1	50	1	50	4.0e-10	56.4	COG0267	Ribosomal protein L33	50
643773428	77	29.09	13	67	17	71	1.0e-07	48.5	COG0690	Preprotein translocase subunit SecE	73
643773429	181	43.58	2	179	1	175	2.0e-37	148	COG0250	Transcription antitermination factor NusG	178
643773430	140	61.43	2	140	1	140	9.0e-48	182	COG0080	Ribosomal protein L11	141
643773431	229	58.15	1	225	1	227	3.0e-79	288	COG0081	Ribosomal protein L1	228
643773432	167	37.97	9	163	5	162	8.0e-26	109	COG0244	Ribosomal protein L10	175
643773433	127	62.9	4	127	1	124	1.0e-25	108	COG0222	Ribosomal protein L7/L12	124
643773435	1436	45.71	18	871	7	806	0.0e+00	786	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
643773436	659	26.89	15	378	1	380	7.0e-42	165	COG0515	Serine/threonine protein kinase	384
643773438	134	75.61	1	123	7	129	4.0e-47	180	COG0048	Ribosomal protein S12	129
643773439	156	59.46	2	149	1	148	1.0e-50	192	COG0049	Ribosomal protein S7	148
643773443	256	17.65	1	253	2	247	6.0e-12	64.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
643773445	427	28.31	16	391	17	395	4.0e-44	172	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
643773447	402	47.07	9	380	5	378	6.0e-113	401	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
643773449	706	64.78	1	705	1	692	0.0e+00	968	COG0480	Translation elongation factor EF-G, a GTPase	697
643773450	400	75.5	1	400	1	394	0.0e+00	654	COG0050	Translation elongation factor EF-Tu, a GTPase	394
643773451	102	68.69	4	102	5	103	4.0e-34	136	COG0051	Ribosomal protein S10	104
643773452	227	42.92	1	225	1	208	9.0e-55	206	COG0087	Ribosomal protein L3	218
643773453	213	44.39	9	210	3	207	5.0e-49	187	COG0088	Ribosomal protein L4	214
643773454	95	46.24	4	95	1	93	5.0e-21	92.6	COG0089	Ribosomal protein L23	94
643773455	276	57.45	1	271	1	275	1.0e-96	346	COG0090	Ribosomal protein L2	275
643773456	96	58.06	1	93	1	93	1.0e-32	131	COG0185	Ribosomal protein S19	93
643773457	125	50	10	125	10	120	5.0e-27	113	COG0091	Ribosomal protein L22	120
643773458	219	62.38	12	211	1	202	1.0e-67	249	COG0092	Ribosomal protein S3	233
643773459	142	64.49	1	136	2	139	1.0e-48	185	COG0197	Ribosomal protein L16/L10AE	146
643773460	67	45.45	2	67	4	69	2.0e-06	43.7	COG0255	Ribosomal protein L29	69
643773461	98	62.2	17	98	5	86	5.0e-25	106	COG0186	Ribosomal protein S17	87
643773462	122	68.85	1	122	1	122	4.0e-45	173	COG0093	Ribosomal protein L14	122
643773463	107	52.88	1	103	2	103	6.0e-19	85.7	COG0198	Ribosomal protein L24	104
643773464	198	56.42	5	183	1	179	2.0e-69	255	COG0094	Ribosomal protein L5	180
643773465	101	55.17	44	101	4	61	4.0e-15	73.3	COG0199	Ribosomal protein S14	61
643773466	133	49.62	1	133	1	132	1.0e-40	158	COG0096	Ribosomal protein S8	132
643773467	179	55.93	1	177	1	177	1.0e-55	209	COG0097	Ribosomal protein L6P/L9E	178
643773468	118	52.59	12	118	10	125	4.0e-26	109	COG0256	Ribosomal protein L18	125
643773469	272	58.43	72	236	13	178	3.0e-52	198	COG0098	Ribosomal protein S5	181
643773470	58	43.4	1	53	1	53	2.0e-07	47	COG1841	Ribosomal protein L30/L7E	55
643773471	160	50.33	13	158	1	148	2.0e-28	118	COG0200	Ribosomal protein L15	152
643773472	448	44.57	10	433	8	432	5.0e-100	358	COG0201	Preprotein translocase subunit SecY	436
643773473	214	39.62	1	212	1	178	3.0e-40	158	COG0563	Adenylate kinase or related kinase	178
643773474	258	50.6	12	258	5	252	2.0e-78	285	COG0024	Methionine aminopeptidase	255
643773475	286	35.14	146	255	8	118	2.0e-16	79.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643773476	138	33.61	10	131	9	127	1.0e-15	75.3	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
643773478	510	51.66	1	300	2	301	1.0e-93	337	COG3643	Glutamate formiminotransferase	302
643773479	276	42.64	9	271	4	260	6.0e-56	211	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
643773480	337	47.9	1	304	5	312	9.0e-102	363	COG0180	Tryptophanyl-tRNA synthetase	314
643773481	345	35.94	31	345	13	324	2.0e-59	222	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
643773482	444	49.43	1	352	3	353	8.0e-112	397	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
643773483	300	36.15	7	300	3	296	3.0e-56	212	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
643773486	431	55.06	7	427	2	426	0.0e+00	564	COG0104	Adenylosuccinate synthase	430
643773487	334	24.05	1	334	3	298	8.0e-22	98.1	COG0492	Thioredoxin reductase	305
643773488	446	40.32	6	446	4	553	0.0e+00	534	COG0423	Glycyl-tRNA synthetase (class II)	558
643773490	235	40.16	1	225	1	241	1.0e-49	189	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
643773491	441	26.29	4	175	1	175	6.0e-10	59.3	COG2203	GAF domain	175
643773494	337	44.14	8	331	5	328	1.0e-65	243	COG0714	MoxR-like ATPase	329
643773500	319	43.63	11	319	1	310	3.0e-69	255	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
643773501	339	35.43	38	339	25	322	5.0e-60	225	COG0598	Mg2+ and Co2+ transporter CorA	322
643773502	309	35.92	27	288	2	282	2.0e-44	172	COG0515	Serine/threonine protein kinase	384
643773503	343	32.6	1	341	4	360	7.0e-55	207	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
643773504	767	43.63	9	766	1	730	0.0e+00	702	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
643773505	395	32.37	17	386	4	382	9.0e-77	281	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
643773506	180	40.13	11	155	22	173	2.0e-31	128	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
643773508	162	41.91	22	157	6	140	8.0e-30	123	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
643773509	241	44.86	5	217	10	219	8.0e-30	123	COG0785	Cytochrome c biogenesis protein CcdA	220
643773510	590	39.86	2	583	1	566	2.0e-125	443	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
643773512	593	44.34	51	593	3	539	0.0e+00	524	COG0405	Gamma-glutamyltranspeptidase	539
643773514	328	54.85	15	313	1	298	6.0e-92	331	COG2103	N-acetylmuramic acid 6-phosphate (MurNAc-6-P) etherase	298
643773515	396	40.47	13	390	8	370	8.0e-70	257	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
643773516	493	36	25	321	18	310	2.0e-47	184	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
643773517	400	41.29	22	285	9	255	7.0e-55	208	COG0631	Serine/threonine protein phosphatase PrpC	262
643773518	609	31.98	397	603	13	230	1.0e-30	128	COG0860	N-acetylmuramoyl-L-alanine amidase	231
643773520	181	54.9	21	173	18	170	2.0e-45	175	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
643773521	859	32.02	14	599	102	654	1.0e-116	414	COG0209	Ribonucleotide reductase alpha subunit	696
643773522	389	29.41	186	349	42	211	2.0e-16	80.4	COG2856	Zn-dependent peptidase ImmA, M78 family	213
643773527	290	27.03	30	284	55	282	1.0e-13	70.5	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
643773528	115	58.26	1	115	1	115	6.0e-43	165	COG4898	Uncharacterized protein	115
643773530	170	26.17	1	142	1	149	3.0e-20	91.6	COG1959	DNA-binding transcriptional regulator, IscR family	150
643773531	302	24.75	8	299	4	300	8.0e-38	150	COG0492	Thioredoxin reductase	305
643773533	356	39.08	12	355	5	339	1.0e-103	370	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
643773537	180	39.01	2	179	1	182	4.0e-24	104	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643773540	551	21.94	323	543	26	251	3.0e-09	57.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643773541	395	44.07	42	395	4	345	7.0e-85	307	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
643773543	524	41.34	17	522	7	587	0.0e+00	497	COG0514	Superfamily II DNA helicase RecQ	590
643773547	445	16.15	36	415	5	352	3.0e-11	63.5	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
643773549	424	25.48	57	389	31	365	5.0e-26	112	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643773550	414	21.78	21	411	5	401	6.0e-29	122	COG1228	Imidazolonepropionase or related amidohydrolase	406
643773557	205	44.12	3	205	29	227	2.0e-47	182	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643773562	83	46.34	1	81	1	82	5.0e-07	46.2	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
643773563	138	29.06	13	127	3	117	1.0e-11	62.6	COG3682	Predicted transcriptional regulator	123
643773564	735	20.65	13	374	6	323	1.0e-17	85.8	COG4219	Signal transducer regulating beta-lactamase production, contains  metallopeptidase domain	337
643773565	450	29.27	149	435	42	304	5.0e-17	82.7	COG1413	HEAT repeat	335
643773567	211	33.91	43	211	2	156	4.0e-28	118	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
643773568	105	52.38	1	105	1	105	2.0e-18	84	COG2076	Multidrug transporter EmrE and related cation transporters	106
643773577	209	47.85	6	206	1	209	2.0e-50	192	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643773581	87	41.67	1	60	3	62	2.0e-10	57.2	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
643773582	409	21.35	34	409	4	382	6.0e-30	125	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643773584	388	22.94	47	377	18	351	9.0e-25	108	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
643773585	148	54.23	1	142	20	161	2.0e-60	224	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
643773586	459	20.72	2	308	1	321	1.0e-14	75	COG4219	Signal transducer regulating beta-lactamase production, contains  metallopeptidase domain	337
643773587	145	32.79	4	120	2	123	8.0e-17	79.5	COG3682	Predicted transcriptional regulator	123
643773589	558	29.1	125	554	48	452	4.0e-59	222	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
643773590	479	21.38	18	473	15	452	2.0e-26	114	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
643773595	328	42.09	1	326	1	325	2.0e-64	239	COG0714	MoxR-like ATPase	329
643773598	376	42.76	111	262	5	155	1.0e-32	134	COG4335	3-methyladenine DNA glycosylase AlkC	167
643773599	301	23.75	2	295	1	292	3.0e-28	119	COG0583	DNA-binding transcriptional regulator, LysR family	297
643773606	221	39.01	1	215	1	222	2.0e-41	162	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643773607	386	34.87	1	386	2	373	1.0e-81	296	COG4637	Predicted ATPase	373
643773608	218	39.29	7	199	5	200	6.0e-47	180	COG0288	Carbonic anhydrase	207
643773609	1590	34.52	250	557	34	338	1.0e-56	216	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
643773610	280	37.25	23	276	31	282	5.0e-39	155	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
643773611	334	35.22	1	318	2	312	3.0e-56	212	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
643773612	544	24.34	1	537	7	556	9.0e-49	188	COG0747	ABC-type transport system, periplasmic component	556
643773614	389	19.86	11	386	25	400	9.0e-16	78.5	COG1228	Imidazolonepropionase or related amidohydrolase	406
643773615	1168	22.04	740	1135	2	400	2.0e-30	128	COG1228	Imidazolonepropionase or related amidohydrolase	406
643773618	404	30.85	27	402	68	467	1.0e-65	244	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
643773620	500	28.09	79	490	5	397	1.0e-36	148	COG0475	Kef-type K+ transport system, membrane component KefB	397
643773621	431	19.44	35	431	9	402	4.0e-08	53.1	COG1228	Imidazolonepropionase or related amidohydrolase	406
643773622	429	29.98	1	428	3	447	2.0e-28	120	COG0531	Amino acid transporter	466
643773623	679	60.92	5	676	4	699	0.0e+00	773	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
643773624	645	19.63	163	607	62	517	3.0e-15	77.4	COG2936	Predicted acyl esterase	563
643773625	658	34.37	124	473	26	351	9.0e-62	231	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
643773626	311	23.68	51	305	23	282	4.0e-09	55.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643773631	238	22.54	3	221	34	272	6.0e-11	61.2	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
643773632	261	28.34	16	259	7	251	4.0e-25	108	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
643773633	774	34.63	29	288	2	281	5.0e-44	173	COG0515	Serine/threonine protein kinase	384
643773634	531	25	298	503	1	186	8.0e-13	69.1	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
643773635	711	46.58	392	709	4	322	2.0e-105	376	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
643773636	264	42.75	1	261	1	257	2.0e-52	199	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
643773637	399	46.69	3	304	2	298	3.0e-81	296	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
643773638	154	31.16	12	145	5	141	1.0e-15	75.8	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
643773639	412	44.88	11	411	6	391	7.0e-86	311	COG0183	Acetyl-CoA acetyltransferase	392
643773640	203	44.83	1	174	3	176	5.0e-46	177	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
643773641	684	27.98	4	508	1	470	4.0e-58	219	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643773642	467	29.35	16	457	13	446	3.0e-45	176	COG0534	Na+-driven multidrug efflux pump	455
643773644	761	22.91	149	755	16	615	2.0e-47	184	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
643773645	975	33.22	394	971	16	536	3.0e-101	363	COG0405	Gamma-glutamyltranspeptidase	539
643773646	146	35.56	4	133	8	142	1.0e-22	99.2	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
643773649	870	18.79	261	863	48	620	2.0e-35	144	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
643773653	396	23.8	22	366	1	370	3.0e-23	103	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643773654	165	26.76	5	138	12	148	9.0e-08	50	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
643773655	276	24.03	47	276	15	271	1.0e-17	83.7	COG1082	Sugar phosphate isomerase/epimerase	274
643773656	565	22.02	8	556	6	533	3.0e-55	209	COG2303	Choline dehydrogenase or related flavoprotein	542
643773659	316	28.43	46	316	4	289	2.0e-40	159	COG1234	Ribonuclease BN, tRNA processing enzyme	292
643773660	412	23.74	4	394	2	342	1.0e-28	121	COG0673	Predicted dehydrogenase	342
643773662	227	41.63	12	219	1	209	1.0e-52	199	COG3142	Copper homeostasis protein CutC	241
643773668	437	30.07	16	416	6	393	2.0e-44	174	COG4102	Uncharacterized conserved protein, DUF1501 family	418
643773669	512	29.95	22	422	31	428	5.0e-49	189	COG5267	Uncharacterized conserved protein, DUF1800 family	496
643773670	434	32.03	5	434	3	397	3.0e-63	235	COG1459	Type II secretory pathway, component PulF	397
643773671	517	45.81	33	509	16	499	0.0e+00	463	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
643773672	621	26.84	68	590	37	553	4.0e-61	229	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
643773681	489	26.23	78	476	21	388	1.0e-29	125	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
643773682	375	22.75	10	364	1	238	2.0e-29	123	COG0176	Transaldolase	239
643773683	466	52.21	1	466	4	477	0.0e+00	520	COG0469	Pyruvate kinase	477
643773684	267	32.12	1	263	4	265	4.0e-32	131	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
643773685	462	30.62	3	453	4	444	9.0e-70	257	COG0166	Glucose-6-phosphate isomerase	446
643773686	484	20.65	98	373	17	245	4.0e-06	46.3	COG0191	Fructose/tagatose bisphosphate aldolase	286
643773688	333	25.17	16	302	16	298	9.0e-24	104	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
643773689	344	41.11	1	336	1	340	2.0e-70	259	COG2008	Threonine aldolase	342
643773690	245	30.27	25	208	6	164	2.0e-20	92.7	COG4185	Predicted ABC-type ATPase	187
643773691	598	36.85	1	499	2	473	3.0e-99	356	COG2812	DNA polymerase III, gamma/tau subunits	515
643773692	104	42.57	1	101	5	105	3.0e-15	73.3	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
643773693	199	50.51	4	199	7	198	1.0e-67	248	COG0353	Recombinational DNA repair protein RecR	198
643773694	163	32.32	31	129	19	116	5.0e-08	51	COG2018	Predicted regulator of Ras-like GTPase activity, Roadblock/LC7/MglB family	119
643773695	225	25.79	3	159	1	147	8.0e-12	64.2	COG2229	Signal recognition particle receptor subunit beta, a GTPase	187
643773696	233	32	1	173	12	151	6.0e-11	61.2	COG0558	Phosphatidylglycerophosphate synthase	192
643773698	157	21.33	7	143	6	155	9.0e-16	76.5	COG1510	DNA-binding transcriptional regulator GbsR, MarR family	177
643773701	428	42.25	1	255	2	255	8.0e-57	214	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
643773702	188	38.73	42	182	49	189	4.0e-29	121	COG0576	Molecular chaperone GrpE (heat shock protein)	193
643773703	379	37.57	5	376	4	352	3.0e-88	319	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
643773706	420	24.75	2	408	1	393	4.0e-44	172	COG1301	Na+/H+-dicarboxylate symporter	415
643773708	406	23.81	13	404	14	379	5.0e-35	142	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
643773709	381	41.71	6	362	1	354	9.0e-102	363	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
643773710	396	47.23	4	381	2	380	4.0e-125	441	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
643773713	212	32.24	1	208	5	215	3.0e-36	145	COG1878	Kynurenine formamidase	218
643773714	243	34.52	1	189	5	199	6.0e-30	124	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
643773715	320	50	13	319	6	302	8.0e-93	333	COG0408	Coproporphyrinogen III oxidase	303
643773716	351	51.59	1	340	6	348	2.0e-105	376	COG0407	Uroporphyrinogen-III decarboxylase	352
643773717	526	34.43	190	498	73	406	1.0e-31	131	COG0840	Methyl-accepting chemotaxis protein	408
643773718	502	35.29	191	488	85	407	3.0e-38	153	COG0840	Methyl-accepting chemotaxis protein	408
643773719	414	23.82	18	414	1	419	8.0e-31	128	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
643773720	413	27.83	18	413	1	419	4.0e-27	116	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
643773721	415	26.24	19	415	1	419	3.0e-31	129	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
643773722	411	26.78	18	411	1	419	3.0e-28	119	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
643773723	417	28.64	26	417	1	419	2.0e-28	120	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
643773724	415	27.53	18	415	1	419	1.0e-32	134	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
643773725	250	53.54	14	237	1	226	3.0e-83	301	COG1136	ABC-type lipoprotein export system, ATPase component	226
643773727	505	20.85	9	501	8	443	3.0e-15	76.7	COG1538	Outer membrane protein TolC	457
643773730	593	31.43	305	557	1	277	4.0e-34	139	COG0515	Serine/threonine protein kinase	384
643773731	446	38.95	191	362	4	175	5.0e-34	139	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
643773732	517	50.87	18	509	7	521	3.0e-121	429	COG4147	Na+(or H+)/acetate symporter ActP	529
643773733	106	38.89	8	96	10	99	2.0e-13	67.6	COG3162	Uncharacterized membrane protein, DUF485 family	102
643773734	147	23.26	6	134	20	146	5.0e-08	50.3	COG4243	Uncharacterized membrane protein	156
643773737	434	27.98	22	262	8	250	2.0e-27	117	COG2966	Uncharacterized membrane protein YjjP, DUF1212 family	250
643773739	553	31.24	47	551	5	572	3.0e-73	269	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
643773740	685	28.12	19	675	1	616	2.0e-84	307	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
643773741	387	32.25	5	357	2	365	1.0e-41	164	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
643773742	346	35.29	221	338	5	122	1.0e-15	77.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643773743	518	51.41	14	508	1	485	0.0e+00	493	COG0606	Predicted ATPase with chaperone activity	490
643773745	457	50.98	1	457	3	463	0.0e+00	509	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643773747	494	45.96	4	485	1	472	0.0e+00	495	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643773748	224	25.31	16	172	5	152	1.0e-12	66.9	COG0681	Signal peptidase I	166
643773749	286	46.13	6	285	58	341	2.0e-70	259	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
643773750	166	49.4	1	166	1	164	1.0e-38	152	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
643773751	131	23.81	1	124	3	127	1.0e-05	42.6	COG4319	Ketosteroid isomerase homolog	137
643773753	473	36	1	439	2	435	1.0e-105	376	COG0621	tRNA A37 methylthiotransferase MiaB	437
643773754	435	54.88	4	429	1	430	0.0e+00	542	COG0001	Glutamate-1-semialdehyde aminotransferase	432
643773755	456	31.61	125	452	97	390	2.0e-41	163	COG2385	Peptidoglycan hydrolase (amidase) enhancer domain	397
643773756	334	34.72	5	333	4	339	2.0e-55	209	COG0673	Predicted dehydrogenase	342
643773758	643	38.89	14	630	3	662	7.0e-113	401	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
643773760	528	46.14	4	519	1	521	0.0e+00	494	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
643773761	296	24.14	11	268	5	247	6.0e-19	88.2	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
643773762	229	36.62	11	218	1	213	3.0e-33	135	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643773763	356	55.43	1	356	1	359	2.0e-129	455	COG0216	Protein chain release factor A	363
643773764	326	34.43	20	323	2	280	4.0e-45	175	COG2890	Methylase of polypeptide chain release factors	280
643773765	116	28.85	2	105	5	108	6.0e-07	46	COG3679	Cell fate regulator YlbF, YheA/YmcA/DUF963 family (controls sporulation, competence, biofilm development)	118
643773766	237	43.33	14	222	3	205	4.0e-52	198	COG0125	Thymidylate kinase	208
643773767	549	39.18	55	366	41	357	1.0e-73	271	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
643773769	230	21.86	12	226	2	207	5.0e-22	98.1	COG2834	Outer membrane lipoprotein-sorting protein	211
643773770	342	54.9	55	336	1	286	2.0e-99	356	COG2876	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	286
643773771	252	26.96	1	249	2	288	2.0e-42	165	COG1234	Ribonuclease BN, tRNA processing enzyme	292
643773773	1191	32.68	1	1153	1	1158	0.0e+00	514	COG1196	Chromosome segregation ATPase	1163
643773776	193	29.19	9	193	1	178	4.0e-10	58.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643773777	879	32.67	94	382	2	282	2.0e-37	151	COG0515	Serine/threonine protein kinase	384
643773781	127	47.12	16	119	10	113	2.0e-30	124	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
643773782	147	49.66	1	147	1	147	7.0e-39	153	COG0359	Ribosomal protein L9	148
643773784	73	55.38	1	65	11	75	3.0e-17	79.9	COG0238	Ribosomal protein S18	75
643773785	130	33	12	109	1	100	3.0e-15	74.1	COG0360	Ribosomal protein S6	112
643773787	366	58.56	1	366	2	372	0.0e+00	468	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
643773794	333	21.65	13	332	11	326	3.0e-14	72.9	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643773796	190	40.96	1	186	2	184	9.0e-48	183	COG0193	Peptidyl-tRNA hydrolase	190
643773797	208	40.22	5	96	3	93	8.0e-19	87.2	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
643773798	322	55.99	17	322	6	314	9.0e-112	396	COG0462	Phosphoribosylpyrophosphate synthetase	314
643773800	304	37.83	7	299	9	305	4.0e-47	181	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
643773801	501	28.43	19	422	26	405	6.0e-55	208	COG1649	Uncharacterized lipoprotein YddW, UPF0748 family	418
643773804	142	29.2	9	141	4	137	3.0e-20	90.7	COG0824	Acyl-CoA thioesterase FadM	137
643773805	660	19.42	26	659	43	767	3.0e-24	107	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643773806	422	27.48	25	422	14	391	5.0e-52	198	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
643773807	182	25.13	3	179	13	195	4.0e-21	94.6	COG4430	Uncharacterized conserved protein YdeI, YjbR/CyaY-like superfamily, DUF1801 family	200
643773812	315	51.93	29	313	1	285	1.0e-93	336	COG1946	Acyl-CoA thioesterase	289
643773813	204	26.79	36	193	37	195	1.0e-13	70	COG4430	Uncharacterized conserved protein YdeI, YjbR/CyaY-like superfamily, DUF1801 family	200
643773814	671	30	549	643	32	126	5.0e-08	53.8	COG0526	Thiol-disulfide isomerase or thioredoxin	127
643773815	789	21.89	36	784	7	751	9.0e-32	132	COG4772	Outer membrane receptor for Fe3+-dicitrate	753
643773817	342	20.6	95	285	17	198	5.0e-14	72.2	COG1647	Esterase/lipase	243
643773818	470	24.4	32	461	1	449	2.0e-51	197	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
643773819	529	26.26	36	525	3	454	2.0e-67	250	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
643773820	291	33.61	65	291	1	235	3.0e-38	152	COG0412	Dienelactone hydrolase	236
643773821	289	28.47	22	286	11	280	1.0e-15	77.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643773822	330	43.94	3	330	1	327	7.0e-89	321	COG1171	Threonine dehydratase	347
643773824	295	35.42	5	272	4	255	6.0e-44	171	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
643773825	338	20.82	8	324	22	314	7.0e-11	62	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
643773827	246	55.6	7	241	2	242	1.0e-74	272	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
643773831	281	46.15	8	280	2	273	6.0e-80	290	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
643773836	713	34.49	9	696	1	639	9.0e-112	398	COG1199	Rad3-related DNA helicase	654
643773837	204	49.05	1	203	56	264	2.0e-58	218	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
643773839	483	38.67	1	477	4	470	2.0e-121	429	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
643773842	168	33.77	12	165	4	156	2.0e-26	111	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
643773843	578	24.04	140	572	7	434	2.0e-40	160	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
643773844	355	24.93	3	343	9	317	6.0e-17	82	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
643773847	101	52.08	1	95	1	96	1.0e-26	111	COG5470	Uncharacterized conserved protein, DUF1330 family	96
643773848	109	47.62	1	105	2	106	3.0e-21	93.6	COG2076	Multidrug transporter EmrE and related cation transporters	106
643773849	251	23	1	210	2	156	3.0e-11	62.3	COG0622	Predicted phosphodiesterase	172
643773851	107	44.3	12	89	16	94	5.0e-12	62.9	COG0640	DNA-binding transcriptional regulator, ArsR family	110
643773854	137	31.85	3	137	8	141	5.0e-21	93.6	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
643773855	335	40.92	29	326	35	329	1.0e-61	230	COG3367	Uncharacterized conserved protein, NAD-dependent epimerase/dehydratase family	339
643773856	250	41.7	21	247	43	276	2.0e-41	162	COG4760	Uncharacterized membrane protein, YccA/Bax inhibitor family	276
643773861	509	58.28	1	509	3	515	0.0e+00	701	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
643773862	239	47.78	1	197	1	196	5.0e-50	191	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
643773863	204	38.89	8	150	7	148	2.0e-32	132	COG0241	Histidinol phosphatase or a related phosphatase	181
643773865	915	49.01	9	913	1	875	0.0e+00	1033	COG0525	Valyl-tRNA synthetase	877
643773867	660	49.59	40	647	1	589	0.0e+00	676	COG0441	Threonyl-tRNA synthetase	589
643773868	415	40.44	232	413	2	181	1.0e-26	114	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
643773870	294	26.77	50	293	4	246	3.0e-20	92.7	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
643773871	403	45.61	5	402	1	392	5.0e-84	304	COG0183	Acetyl-CoA acetyltransferase	392
643773873	292	54.61	12	292	2	283	6.0e-100	357	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
643773874	394	48.83	6	382	5	387	1.0e-94	340	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643773875	358	32.98	10	340	36	401	5.0e-77	281	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
643773876	160	50	7	154	2	151	1.0e-44	172	COG0698	Ribose 5-phosphate isomerase RpiB	151
643773877	432	65.77	21	427	7	413	0.0e+00	636	COG0112	Glycine/serine hydroxymethyltransferase	413
643773879	538	35.06	212	518	13	281	4.0e-43	169	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
643773881	323	39.18	22	319	4	317	3.0e-51	195	COG0611	Thiamine monophosphate kinase	317
643773882	269	31.65	11	243	1	231	2.0e-31	129	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
643773883	426	66.51	1	424	1	420	0.0e+00	637	COG0148	Enolase	423
643773884	126	27.06	6	90	34	117	9.0e-06	42.6	COG2919	Cell division protein FtsB	117
643773888	496	27.46	82	475	52	439	8.0e-43	168	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
643773891	726	43.4	36	725	23	713	0.0e+00	571	COG2217	Cation transport ATPase	713
643773892	1088	45.17	23	1065	2	1025	0.0e+00	1047	COG3696	Cu/Ag efflux pump CusA	1027
643773893	432	28.13	83	421	24	361	9.0e-14	71.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643773894	444	19.17	1	429	19	441	1.0e-08	54.8	COG1538	Outer membrane protein TolC	457
643773895	118	42.22	30	118	14	103	6.0e-11	59.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
643773898	1080	45.19	1	1078	1	1027	0.0e+00	1118	COG3696	Cu/Ag efflux pump CusA	1027
643773899	444	30.59	35	356	18	353	1.0e-21	98.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643773900	475	25.42	53	464	30	443	8.0e-25	108	COG1538	Outer membrane protein TolC	457
643773902	124	34.4	1	124	4	125	2.0e-15	74.6	COG2372	Copper-binding protein CopC (methionine-rich)	127
643773905	350	23.51	18	248	1	265	1.0e-06	47.6	COG0501	Zn-dependent protease with chaperone function	302
643773906	138	23.58	15	137	3	123	1.0e-08	52.2	COG3682	Predicted transcriptional regulator	123
643773907	455	26.61	69	421	31	368	3.0e-35	142	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
643773908	457	23.12	80	454	62	444	1.0e-16	81.7	COG1538	Outer membrane protein TolC	457
643773909	323	26.37	8	316	1	287	1.0e-10	61.1	COG1276	Putative copper export protein	289
643773910	702	41.83	3	699	35	709	0.0e+00	583	COG2217	Cation transport ATPase	713
643773914	1112	15.75	254	977	129	778	6.0e-17	83.7	COG1002	Type II restriction/modification system, DNA methylase subunit YeeA	786
643773918	561	26.14	131	443	11	292	1.0e-13	72.2	COG4974	Site-specific recombinase XerD	300
643773919	166	32.88	8	150	18	163	3.0e-21	94.6	COG0835	Chemotaxis signal transduction protein	165
643773920	506	31.73	13	278	4	268	3.0e-49	189	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
643773921	165	28.76	14	162	1	153	5.0e-19	87.3	COG0835	Chemotaxis signal transduction protein	165
643773924	367	44.25	11	355	2	336	8.0e-73	267	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
643773932	579	30.89	102	577	3	475	2.0e-67	250	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
643773934	569	50	4	557	9	572	0.0e+00	681	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
643773937	506	22.92	147	358	16	252	6.0e-12	66.1	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
643773938	748	28.04	77	718	8	617	1.0e-69	258	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
643773944	317	22.06	6	265	32	289	2.0e-10	60	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
643773945	454	22.84	7	454	24	479	5.0e-10	59.5	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
643773946	268	38.37	9	252	3	238	1.0e-55	210	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
643773947	404	33.78	4	370	1	369	2.0e-70	259	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
643773950	508	37.96	26	503	3	485	7.0e-114	404	COG0297	Glycogen synthase	487
643773951	726	32.3	26	712	6	703	0.0e+00	538	COG0058	Glucan phosphorylase	750
643773952	850	38.71	23	484	5	447	3.0e-105	376	COG0527	Aspartokinase	447
643773953	445	38.74	22	430	7	400	7.0e-85	308	COG0498	Threonine synthase	411
643773954	245	21.39	1	198	1	187	3.0e-11	62.6	COG0300	Short-chain dehydrogenase	265
643773958	760	27.54	69	750	2	617	5.0e-74	272	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
643773960	827	29.75	32	822	8	768	3.0e-97	350	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
643773961	325	33.33	1	316	2	319	3.0e-46	179	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
643773962	165	18.75	35	160	16	139	6.0e-09	53.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
643773963	399	22.85	34	365	38	367	4.0e-20	92.7	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
643773964	160	24.19	38	160	11	128	7.0e-10	57	COG3794	Plastocyanin	128
643773966	253	34.62	8	234	2	235	1.0e-54	206	COG1131	ABC-type multidrug transport system, ATPase component	293
643773967	443	28.77	27	443	1	405	2.0e-51	196	COG3420	Nitrous oxidase accessory protein NosD, contains tandem CASH domains	408
643773970	704	30.19	11	653	6	637	5.0e-69	256	COG4263	Nitrous oxide reductase	637
643773971	152	42.75	1	137	1	137	6.0e-27	113	COG1959	DNA-binding transcriptional regulator, IscR family	150
643773973	175	34.66	11	171	7	182	8.0e-24	103	COG0693	Putative intracellular protease/amidase	188
643773974	136	51.79	1	112	1	112	8.0e-32	129	COG0347	Nitrogen regulatory protein PII	112
643773975	464	54.13	29	438	1	409	7.0e-117	414	COG0004	Ammonia channel protein AmtB	409
643773976	468	33.05	29	249	22	256	2.0e-30	127	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
643773977	169	45.83	1	168	7	174	3.0e-52	197	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
643773978	658	53.54	20	621	2	596	0.0e+00	705	COG0465	ATP-dependent Zn proteases	596
643773979	273	44.83	12	241	13	244	9.0e-53	200	COG1624	Diadenylate cyclase (c-di-AMP synthetase), DisA_N domain	247
643773981	224	42.67	4	224	3	227	8.0e-64	236	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
643773983	272	39.48	6	272	1	262	1.0e-58	219	COG0005	Purine nucleoside phosphorylase	262
643773984	1097	35.54	5	1015	1	933	0.0e+00	834	COG0060	Isoleucyl-tRNA synthetase	933
643773985	127	34.92	1	126	1	116	1.0e-13	68.5	COG1734	RNA polymerase-binding transcription factor DksA	120
643773986	187	33.78	18	164	16	160	5.0e-23	101	COG0597	Lipoprotein signal peptidase	167
643773987	162	32.03	1	152	11	160	1.0e-24	106	COG0597	Lipoprotein signal peptidase	167
643773988	329	48.95	16	297	10	288	2.0e-79	289	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
643773991	659	33.99	12	659	9	706	1.0e-124	440	COG0643	Chemotaxis protein histidine kinase CheA	716
643773992	206	38.42	1	203	1	199	5.0e-31	127	COG1776	Chemotaxis protein CheY-P-specific phosphatase CheC	203
643773995	229	23.38	11	193	4	188	5.0e-11	61.5	COG1100	GTPase SAR1 family domain	219
643773998	171	33.13	11	171	5	164	1.0e-27	115	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
643773999	379	46.54	4	364	3	348	5.0e-84	304	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
643774000	168	19.38	19	168	4	162	1.0e-08	53	COG0835	Chemotaxis signal transduction protein	165
643774006	315	44.95	15	311	6	308	6.0e-84	304	COG0275	16S rRNA C1402 N4-methylase RsmH	314
643774008	839	29.39	34	591	14	598	2.0e-86	314	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
643774009	514	43.16	33	504	16	472	6.0e-110	391	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
643774010	474	37.8	26	468	3	448	1.0e-86	314	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
643774011	380	42.23	20	380	1	316	1.0e-54	207	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
643774012	464	37.75	12	461	10	444	4.0e-103	368	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
643774013	398	34.13	13	384	8	375	1.0e-56	213	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
643774014	377	30.3	5	365	2	356	7.0e-60	224	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
643774015	501	43.23	38	493	5	459	2.0e-122	432	COG0773	UDP-N-acetylmuramate-alanine ligase	459
643774017	418	41.71	1	418	2	418	4.0e-102	365	COG0849	Cell division ATPase FtsA	418
643774018	488	32.61	13	467	3	442	3.0e-44	173	COG0531	Amino acid transporter	466
643774020	245	48.05	14	243	3	226	4.0e-58	218	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643774025	416	57.98	2	327	1	325	2.0e-103	369	COG0206	Cell division GTPase FtsZ	338
643774028	309	48.29	20	308	49	340	7.0e-92	330	COG0552	Signal recognition particle GTPase	340
643774029	706	46.67	17	686	2	671	0.0e+00	692	COG1200	RecG-like helicase	677
643774033	433	51.26	5	433	4	435	0.0e+00	520	COG0017	Aspartyl/asparaginyl-tRNA synthetase	435
643774035	403	38.44	6	393	4	360	1.0e-66	247	COG0787	Alanine racemase	360
643774036	391	48.1	6	389	3	397	3.0e-127	448	COG1015	Phosphopentomutase	397
643774037	136	48.03	9	134	7	133	4.0e-35	140	COG0295	Cytidine deaminase	134
643774040	451	43.86	4	435	2	437	0.0e+00	473	COG0621	tRNA A37 methylthiotransferase MiaB	437
643774041	776	33.8	491	772	25	292	1.0e-54	208	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
643774042	360	53.09	10	332	2	321	7.0e-115	407	COG0158	Fructose-1,6-bisphosphatase	326
643774043	531	58.49	6	531	27	548	0.0e+00	620	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
643774044	665	19.87	319	601	96	370	5.0e-10	60	COG5276	Uncharacterized conserved protein	370
643774045	409	23.38	103	402	23	300	1.0e-05	44.8	COG3391	DNA-binding beta-propeller fold protein YncE	381
643774046	370	27.96	98	351	5	279	4.0e-40	158	COG0287	Prephenate dehydrogenase	279
643774053	561	41.26	12	561	1	577	0.0e+00	516	COG0018	Arginyl-tRNA synthetase	577
643774054	312	23.81	9	299	1	309	2.0e-16	79.9	COG0524	Sugar or nucleoside kinase, ribokinase family	311
643774055	350	47.18	9	343	4	339	4.0e-109	388	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
643774057	384	58.11	22	168	3	146	9.0e-49	187	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
643774058	227	43.35	1	202	1	198	1.0e-49	190	COG0307	Riboflavin synthase alpha chain	204
643774059	420	60.62	226	418	2	193	2.0e-73	269	COG0807	GTP cyclohydrolase II	193
643774059	420	61.76	23	225	3	203	2.0e-75	276	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
643774060	164	54	1	150	1	150	3.0e-43	168	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
643774061	157	35.66	23	157	6	148	4.0e-21	94.2	COG0781	Transcription termination factor NusB	151
643774062	382	31.73	28	381	12	381	9.0e-39	154	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643774063	324	41.25	12	314	6	307	1.0e-77	283	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
643774064	125	27.34	3	123	2	129	3.0e-10	57.6	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
643774065	164	34.18	1	158	1	157	2.0e-28	118	COG3444	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB	159
643774068	88	52.27	1	88	1	88	5.0e-23	99.1	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
643774069	578	44.64	4	570	2	568	0.0e+00	565	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
643774070	390	65.58	1	390	1	387	0.0e+00	619	COG0192	S-adenosylmethionine synthetase	388
643774071	171	38.41	1	135	3	140	2.0e-25	108	COG1259	Bifunctional DNase/RNase	151
643774073	308	23.96	5	301	4	314	1.0e-31	130	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
643774074	331	41.98	10	328	6	328	4.0e-49	188	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
643774075	275	44.62	11	269	1	258	4.0e-71	261	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
643774076	249	26.42	8	246	10	248	2.0e-31	129	COG1381	Recombinational DNA repair protein (RecF pathway)	251
643774078	871	55.45	6	865	1	786	0.0e+00	945	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
643774080	144	55.63	1	142	12	152	4.0e-38	150	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
643774082	320	30.56	9	320	1	324	2.0e-49	190	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
643774086	98	33.33	1	97	1	98	2.0e-06	44.5	COG2963	Transposase and inactivated derivatives	116
643774087	288	35.68	57	283	19	225	3.0e-20	92.4	COG2801	Transposase InsO and inactivated derivatives	232
643774088	295	21.11	107	283	60	227	7.0e-06	45	COG2801	Transposase InsO and inactivated derivatives	232
643774095	396	22.51	4	394	10	394	1.0e-14	74.9	COG2814	Predicted arabinose efflux permease, MFS family	394
643774096	150	39.42	20	123	5	108	2.0e-26	112	COG1733	DNA-binding transcriptional regulator, HxlR family	120
643774097	285	38.27	1	267	1	275	2.0e-30	126	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
643774098	512	22.26	188	491	79	394	8.0e-21	95.4	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
643774102	183	56.18	4	180	2	179	3.0e-48	184	COG2065	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	179
643774103	319	49.68	1	307	2	314	7.0e-101	360	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
643774104	431	41.51	7	429	2	421	4.0e-122	431	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
643774105	247	31.98	16	234	10	212	4.0e-29	121	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
643774108	227	37.1	9	189	18	192	8.0e-16	77.4	COG1994	Zn-dependent protease (includes SpoIVFB)	230
643774109	249	38.27	14	247	2	243	4.0e-33	135	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
643774110	184	50.3	1	169	6	172	1.0e-40	159	COG1386	Chromosome segregation and condensation protein ScpB	184
643774111	237	42.45	1	235	3	246	2.0e-53	202	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
643774112	347	44.98	31	347	9	328	6.0e-64	238	COG0714	MoxR-like ATPase	329
643774115	326	23.64	30	275	26	251	2.0e-09	56.8	COG1240	Mg-chelatase subunit ChlD	261
643774118	607	36.6	1	606	1	637	0.0e+00	475	COG0323	DNA mismatch repair ATPase MutL	638
643774119	346	39.47	21	319	8	303	1.0e-66	247	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
643774120	376	30.08	1	375	4	379	2.0e-38	153	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643774121	267	40.74	1	266	4	270	2.0e-60	225	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
643774122	241	32.37	21	241	1	236	2.0e-36	146	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
643774123	97	62.37	5	96	2	94	2.0e-28	117	COG0234	Co-chaperonin GroES (HSP10)	96
643774124	543	49.82	1	535	1	524	0.0e+00	492	COG0459	Chaperonin GroEL (HSP60 family)	524
643774125	280	25.79	1	236	3	252	2.0e-20	93.2	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
643774127	349	32.93	6	326	5	331	2.0e-73	269	COG0836	Mannose-1-phosphate guanylyltransferase	333
643774129	117	27.03	7	117	9	119	3.0e-07	47.1	COG2018	Predicted regulator of Ras-like GTPase activity, Roadblock/LC7/MglB family	119
643774131	425	52.12	1	420	1	420	0.0e+00	501	COG0172	Seryl-tRNA synthetase	429
643774133	820	45.76	27	673	1	654	0.0e+00	574	COG0210	Superfamily I DNA or RNA helicase	655
643774134	107	35.87	1	90	1	92	1.0e-13	68.3	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
643774135	465	53.63	15	461	27	470	2.0e-116	412	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
643774136	479	51.68	1	474	2	476	0.0e+00	639	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
643774139	431	41.27	6	427	4	419	2.0e-121	429	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
643774140	247	34.98	1	235	1	245	6.0e-33	134	COG1496	Copper oxidase (laccase) domain	249
643774141	155	39.87	3	153	12	153	2.0e-25	108	COG0779	Ribosome maturation factor RimP	153
643774142	438	49.18	161	342	1	177	2.0e-41	163	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
643774143	116	31	1	99	7	106	2.0e-08	51.5	COG1358	Ribosomal protein L7Ae or related RNA K-turn-binding protein	116
643774144	1033	56.47	522	1029	1	509	0.0e+00	624	COG0532	Translation initiation factor IF-2, a GTPase	509
643774145	146	42.02	1	118	1	118	2.0e-23	101	COG0858	Ribosome-binding factor A	118
643774146	310	31.8	12	291	12	256	2.0e-44	173	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
643774147	326	44.37	15	307	16	303	3.0e-78	285	COG0196	FAD synthase	304
643774148	556	35.48	46	556	36	506	1.0e-77	284	COG0342	Preprotein translocase subunit SecD	506
643774149	334	38.67	8	307	8	297	1.0e-70	260	COG0341	Preprotein translocase subunit SecF	305
643774150	276	41.63	6	258	3	256	7.0e-71	260	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
643774151	130	49.23	1	129	1	130	5.0e-31	126	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
643774153	252	27.04	11	237	5	234	3.0e-22	99.2	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
643774154	170	36.62	13	153	1	136	6.0e-28	116	COG0824	Acyl-CoA thioesterase FadM	137
643774155	144	38.97	8	138	1	136	4.0e-34	136	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
643774159	247	49.38	1	242	1	230	6.0e-61	227	COG0689	Ribonuclease PH	230
643774160	234	39.9	17	223	4	191	8.0e-42	163	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
643774172	335	64.29	88	325	1	238	2.0e-93	336	COG1186	Protein chain release factor B	239
643774173	523	53.85	30	523	8	501	0.0e+00	604	COG1190	Lysyl-tRNA synthetase (class II)	502
643774174	416	36.6	3	416	4	408	5.0e-83	301	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
643774175	250	42.29	17	242	1	226	1.0e-68	253	COG1136	ABC-type lipoprotein export system, ATPase component	226
643774176	161	27.49	1	161	1	168	1.0e-20	92.7	COG3880	Protein-arginine kinase activator protein McsA	176
643774177	366	40.29	18	358	11	349	2.0e-78	286	COG3869	Protein-arginine kinase	352
643774178	835	51.64	6	825	2	781	0.0e+00	915	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
643774179	817	23.86	36	817	24	766	2.0e-88	320	COG4775	Outer membrane protein assembly factor BamA	766
643774180	205	23.95	6	170	5	167	6.0e-09	54.2	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
643774181	360	43.2	20	357	1	338	2.0e-84	306	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
643774182	424	43.43	3	272	2	275	8.0e-76	277	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
643774183	262	48.64	6	261	3	259	2.0e-85	308	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
643774184	350	31.4	17	335	5	338	6.0e-36	144	COG0673	Predicted dehydrogenase	342
643774185	375	38.79	1	368	1	378	9.0e-94	337	COG0763	Lipid A disaccharide synthetase	381
643774186	244	31.38	33	218	10	195	2.0e-38	152	COG2121	Uncharacterized conserved protein, lysophospholipid acyltransferase (LPLAT) superfamily	214
643774187	358	29.31	28	338	19	321	4.0e-41	162	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
643774188	393	44.77	25	392	1	411	5.0e-124	438	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
643774189	154	40	1	154	1	155	1.0e-40	159	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
643774190	537	22.84	67	518	58	521	5.0e-37	149	COG4365	Uncharacterized protein YllA, UPF0747 family	537
643774191	524	32.3	8	520	11	515	6.0e-73	268	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
643774192	616	47.22	6	595	8	581	0.0e+00	570	COG0322	Excinuclease UvrABC, nuclease subunit	581
643774193	381	34.47	7	377	5	373	1.0e-60	227	COG0498	Threonine synthase	411
643774194	435	28.11	1	427	2	414	1.0e-47	183	COG1625	Fe-S oxidoreductase, related to NifB/MoaA family	414
643774195	436	49.66	1	436	1	440	0.0e+00	502	COG1160	Predicted GTPases	444
643774196	211	40.69	6	202	3	200	2.0e-31	128	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
643774197	338	52.89	8	336	1	329	1.0e-105	376	COG0240	Glycerol-3-phosphate dehydrogenase	329
643774198	129	30.19	13	118	1	105	2.0e-10	57.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
643774199	252	51	1	248	1	250	3.0e-79	288	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
643774200	219	52.68	14	217	3	207	6.0e-61	227	COG2518	Protein-L-isoaspartate O-methyltransferase	209
643774202	178	50.9	1	167	2	164	1.0e-40	159	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
643774205	220	20.77	12	217	4	206	1.0e-07	50.3	COG2976	Putative negative regulator of RcsB-dependent stress response	207
643774206	277	29.97	1	276	1	272	1.0e-40	160	COG0253	Diaminopimelate epimerase	272
643774207	250	24.68	17	250	7	228	9.0e-18	84	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
643774210	407	32.52	89	398	54	379	6.0e-38	152	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643774212	497	36.22	1	496	1	442	5.0e-105	375	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
643774213	280	64.41	15	248	3	238	1.0e-96	346	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
643774216	323	55.5	9	207	1	200	6.0e-58	217	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
643774217	211	41.28	22	193	5	169	2.0e-40	158	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
643774218	278	53.21	14	278	17	272	3.0e-88	318	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
643774219	564	65.54	14	546	1	533	0.0e+00	885	COG0504	CTP synthase (UTP-ammonia lyase)	533
643774220	258	43.8	1	240	2	238	4.0e-66	244	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
643774221	311	28.22	65	305	18	239	2.0e-36	146	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
643774223	198	60.53	1	190	3	191	7.0e-79	286	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
643774224	312	52.05	22	312	9	300	4.0e-95	341	COG4974	Site-specific recombinase XerD	300
643774225	207	26.04	14	204	17	208	1.0e-16	80.3	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
643774226	166	53.25	5	158	1	154	4.0e-52	197	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
643774227	356	42.6	1	333	23	360	8.0e-104	370	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
643774228	282	30	1	269	2	245	4.0e-37	148	COG1427	Predicted periplasmic solute-binding protein	252
643774229	401	40.49	15	380	6	368	1.0e-90	326	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
643774230	413	55.93	1	411	1	411	0.0e+00	473	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
643774231	79	56.58	1	76	3	78	6.0e-12	62.3	COG0236	Acyl carrier protein	80
643774232	252	53.54	6	251	1	251	2.0e-46	179	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643774233	317	47.08	5	311	4	309	2.0e-73	269	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
643774234	330	52.31	6	330	4	322	1.0e-102	366	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
643774235	346	43.93	1	334	1	333	5.0e-89	321	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
643774236	60	54.72	1	53	1	53	2.0e-09	54.5	COG0333	Ribosomal protein L32	57
643774237	170	26.28	11	162	16	170	7.0e-14	70.4	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
643774238	141	47.37	4	136	3	135	1.0e-42	165	COG0105	Nucleoside diphosphate kinase	135
643774239	297	34.85	163	291	1	117	4.0e-14	72.5	COG0517	CBS domain	117
643774240	290	61.51	1	290	1	290	1.0e-107	382	COG0074	Succinyl-CoA synthetase, alpha subunit	293
643774241	381	53.91	1	375	1	384	3.0e-124	438	COG0045	Succinyl-CoA synthetase, beta subunit	387
643774243	459	35.85	1	454	3	459	4.0e-98	351	COG1109	Phosphomannomutase	464
643774244	520	39.67	11	494	5	470	2.0e-81	296	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
643774245	521	40.76	11	505	5	487	1.0e-108	387	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
643774246	674	40.98	6	670	1	606	1.0e-112	401	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
643774247	97	56.12	1	97	3	100	5.0e-18	82.8	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
643774248	168	41.72	4	165	3	165	2.0e-17	81.8	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
643774250	418	51.8	2	335	16	332	6.0e-91	328	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
643774252	442	53.9	5	425	3	421	0.0e+00	559	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
643774253	155	42.58	1	155	4	157	8.0e-46	176	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
643774254	394	53.81	1	394	5	398	0.0e+00	516	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
643774255	213	41.29	4	158	2	151	2.0e-30	125	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
643774256	212	58.82	18	169	13	164	4.0e-60	224	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
643774257	134	46.27	1	134	4	121	1.0e-21	95.6	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
643774258	184	41.08	5	184	4	181	2.0e-55	208	COG0717	Deoxycytidine triphosphate deaminase	183
643774259	441	30.36	14	291	5	282	6.0e-31	128	COG1808	Uncharacterized membrane protein	334
643774261	297	34.88	17	272	1	280	4.0e-42	165	COG3258	Cytochrome c	293
643774262	257	27.39	1	238	1	225	1.0e-32	133	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
643774263	637	30.91	29	627	1	562	1.0e-92	334	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
643774265	309	45.87	3	302	1	302	2.0e-100	358	COG0039	Malate/lactate dehydrogenase	313
643774266	323	42.94	1	323	2	322	5.0e-90	324	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
643774267	165	41.61	1	148	1	148	4.0e-32	130	COG0314	Molybdopterin synthase catalytic subunit	149
643774268	80	26.44	2	80	1	84	4.0e-07	46.5	COG1977	Molybdopterin converting factor, small subunit	84
643774269	110	47.42	1	97	2	92	3.0e-23	99.8	COG0776	Bacterial nucleoid DNA-binding protein	94
643774270	377	52.3	7	370	3	367	0.0e+00	494	COG0505	Carbamoylphosphate synthase small subunit	368
643774271	136	35.8	1	81	1	78	4.0e-12	64.1	COG1314	Preprotein translocase subunit SecG	86
643774272	251	49.8	4	251	3	246	5.0e-68	251	COG0149	Triosephosphate isomerase	251
643774273	398	56.47	1	398	2	393	0.0e+00	494	COG0126	3-phosphoglycerate kinase	395
643774274	337	60.24	2	337	1	334	7.0e-129	453	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
643774275	285	32.3	14	270	5	224	8.0e-29	120	COG1040	Predicted amidophosphoribosyltransferases	225
643774276	293	37.72	2	282	1	279	2.0e-60	225	COG0169	Shikimate 5-dehydrogenase	283
643774277	157	36.11	1	144	3	137	3.0e-30	124	COG0394	Protein-tyrosine-phosphatase	139
643774278	224	31.55	14	218	9	209	4.0e-35	141	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
643774279	257	43.05	31	252	3	225	2.0e-52	199	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
643774280	465	51.94	1	462	1	456	0.0e+00	549	COG1066	Predicted ATP-dependent serine protease	456
643774281	488	52.8	11	456	1	434	0.0e+00	494	COG0305	Replicative DNA helicase	435
643774282	293	48.44	97	275	8	199	2.0e-42	165	COG1573	Uracil-DNA glycosylase	202
643774284	215	49.73	6	188	7	188	3.0e-59	221	COG0194	Guanylate kinase	191
643774285	290	41.3	1	290	1	290	2.0e-61	229	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
643774287	501	41.18	9	500	2	485	1.0e-125	443	COG0260	Leucyl aminopeptidase	485
643774292	184	40.11	12	184	1	177	5.0e-22	97.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643774293	238	32.94	11	238	5	257	3.0e-31	128	COG0584	Glycerophosphoryl diester phosphodiesterase	257
643774295	97	62.35	1	85	1	85	7.0e-31	125	COG0211	Ribosomal protein L27	87
643774296	105	52.48	3	103	2	102	3.0e-29	119	COG0261	Ribosomal protein L21	103
643774297	520	40.12	3	501	2	477	3.0e-110	392	COG1530	Ribonuclease G or E	487
643774298	405	46.67	7	403	5	390	1.0e-100	360	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643774300	835	40.17	5	344	5	346	2.0e-75	277	COG0826	Collagenase-like protease, PrtC family	347
643774304	538	40.34	4	520	10	512	0.0e+00	486	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
643774305	137	54.62	3	132	11	140	1.0e-36	145	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
643774307	353	42.81	9	331	1	317	6.0e-84	304	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
643774308	319	28.36	3	319	9	340	5.0e-37	148	COG1253	Hemolysin or related protein, contains CBS domains	429
643774309	432	34.18	78	424	78	428	2.0e-60	226	COG1253	Hemolysin or related protein, contains CBS domains	429
643774310	167	32.58	36	164	20	149	2.0e-27	115	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
643774311	326	50.32	21	324	22	333	6.0e-85	307	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
643774312	593	51.53	6	588	1	583	0.0e+00	736	COG0173	Aspartyl-tRNA synthetase	585
643774314	360	45.43	5	346	2	347	1.0e-103	370	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
643774316	167	24.57	1	166	14	182	3.0e-16	78	COG1713	HD superfamily phosphohydrolase YqeK (fused to NMNAT in mycoplasms)	187
643774317	271	46.59	16	270	2	265	7.0e-71	260	COG0159	Tryptophan synthase alpha chain	265
643774318	484	27.81	117	434	31	344	9.0e-45	174	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
643774320	407	65.21	15	402	2	389	0.0e+00	657	COG0133	Tryptophan synthase beta chain	396
643774321	232	41.36	9	227	2	208	1.0e-45	176	COG0135	Phosphoribosylanthranilate isomerase	208
643774322	281	52.27	55	272	35	254	6.0e-62	231	COG0134	Indole-3-glycerol phosphate synthase	254
643774323	202	42.36	1	202	2	200	3.0e-45	175	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
643774324	345	48.8	9	342	7	338	5.0e-89	321	COG0547	Anthranilate phosphoribosyltransferase	338
643774326	259	42.57	3	251	1	245	2.0e-61	229	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
643774327	474	39.83	33	379	12	347	2.0e-59	223	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
643774328	485	34.36	19	465	1	438	3.0e-97	349	COG0015	Adenylosuccinate lyase	438
643774329	314	31.29	12	300	3	247	8.0e-54	204	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
643774330	216	39.55	1	214	27	238	1.0e-37	150	COG0688	Phosphatidylserine decarboxylase	239
643774331	301	31.65	18	248	1	225	2.0e-42	166	COG1183	Phosphatidylserine synthase	234
643774332	85	45.45	3	79	1	77	2.0e-20	90.6	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
643774333	234	59.57	1	229	3	231	7.0e-89	320	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
643774334	771	48.95	15	718	14	716	0.0e+00	831	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
643774335	460	52.05	1	456	4	464	0.0e+00	543	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
643774338	349	41.4	15	324	12	319	3.0e-82	299	COG0042	tRNA-dihydrouridine synthase	323
643774339	150	32.89	2	148	1	149	7.0e-24	103	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
643774341	453	36.12	2	442	7	446	5.0e-63	235	COG0534	Na+-driven multidrug efflux pump	455
643774343	245	21.5	13	223	18	223	3.0e-18	85.7	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
643774344	311	36.82	18	292	6	276	6.0e-61	227	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
643774345	325	52.5	23	302	5	282	4.0e-88	318	COG1072	Panthothenate kinase	283
643774346	371	34.93	34	367	9	337	1.0e-92	333	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
643774347	957	37.32	181	918	1	649	0.0e+00	583	COG0209	Ribonucleotide reductase alpha subunit	696
643774348	513	69.38	194	513	1	315	0.0e+00	542	COG0519	GMP synthase, PP-ATPase domain/subunit	315
643774349	170	29.67	1	167	2	167	2.0e-20	92	COG0622	Predicted phosphodiesterase	172
643774350	423	43.77	6	392	4	393	9.0e-108	384	COG0019	Diaminopimelate decarboxylase	394
643774351	489	29.72	6	489	10	499	3.0e-107	382	COG0442	Prolyl-tRNA synthetase	500
643774352	434	34.16	1	395	2	392	1.0e-81	297	COG0124	Histidyl-tRNA synthetase	429
643774353	430	39.13	1	427	4	425	5.0e-91	328	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
643774354	289	57.69	1	280	1	286	1.0e-101	363	COG0777	Acetyl-CoA carboxylase beta subunit	294
643774355	421	40.88	7	413	9	373	3.0e-66	246	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
643774356	586	30.62	1	575	6	590	2.0e-104	373	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
643774358	381	23.93	10	272	8	279	2.0e-19	90	COG1792	Cell shape-determining protein MreC	284
643774359	345	62.46	11	339	3	335	1.0e-122	432	COG1077	Actin-like ATPase involved in cell morphogenesis	342
643774360	371	64.95	1	368	1	368	0.0e+00	510	COG0686	Alanine dehydrogenase	371
643774361	429	31.34	15	426	14	431	4.0e-78	285	COG0612	Predicted Zn-dependent peptidase	438
643774362	732	55.14	1	691	4	692	0.0e+00	886	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
643774363	86	59.76	4	85	7	88	5.0e-24	102	COG0184	Ribosomal protein S15P/S13E	89
643774364	534	26.12	12	368	1	376	7.0e-45	175	COG0515	Serine/threonine protein kinase	384
643774367	397	29.98	7	395	5	374	2.0e-40	160	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
643774368	409	49.21	37	409	4	382	0.0e+00	466	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
643774369	288	32.36	7	281	5	265	4.0e-29	121	COG0575	CDP-diglyceride synthetase	265
643774370	258	53.56	18	256	7	245	9.0e-84	303	COG0020	Undecaprenyl pyrophosphate synthase	245
643774371	184	54.01	1	184	1	187	7.0e-55	206	COG0233	Ribosome recycling factor	187
643774372	245	56.36	11	245	2	237	9.0e-86	309	COG0528	Uridylate kinase	238
643774373	295	39.73	3	294	2	277	3.0e-68	252	COG0264	Translation elongation factor EF-Ts	296
643774374	320	53.15	1	254	1	252	3.0e-87	315	COG0052	Ribosomal protein S2	252
643774375	129	56.59	1	129	2	130	2.0e-40	157	COG0103	Ribosomal protein S9	130
643774376	149	60.56	1	141	1	141	2.0e-48	184	COG0102	Ribosomal protein L13	148
643774377	118	52.68	1	112	1	100	2.0e-27	114	COG1970	Large-conductance mechanosensitive channel	130
643774379	468	27.6	31	455	7	432	2.0e-61	230	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
643774380	511	58.77	1	473	1	473	0.0e+00	630	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
643774381	512	57.06	1	512	11	526	0.0e+00	683	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
643774387	585	45.37	42	567	1	519	0.0e+00	481	COG0539	Ribosomal protein S1	541
643774388	672	41.36	5	424	9	422	7.0e-107	381	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
643774389	283	38.49	39	283	39	269	1.0e-42	166	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
643774390	296	46.49	1	296	1	299	2.0e-80	292	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
643774391	243	37.41	11	237	1	264	8.0e-41	160	COG0289	Dihydrodipicolinate reductase	266
643774392	451	36.38	1	449	3	447	3.0e-94	339	COG0527	Aspartokinase	447
643774393	358	37.4	8	347	2	334	6.0e-74	271	COG0136	Aspartate-semialdehyde dehydrogenase	334
643774394	330	29.4	1	330	12	408	8.0e-35	141	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643774410	447	23.74	8	281	6	266	4.0e-25	109	COG0270	Site-specific DNA-cytosine methylase	328
643774412	155	28.57	6	155	4	167	4.0e-23	100	COG0629	Single-stranded DNA-binding protein	167
643774453	323	26.05	2	251	9	258	3.0e-18	85.9	COG5377	Phage-related protein, predicted endonuclease	319
643774458	347	42.05	4	330	10	360	4.0e-87	314	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
643774459	745	37.26	72	383	31	335	2.0e-42	167	COG0642	Signal transduction histidine kinase	336
643774460	266	33.91	22	254	7	236	2.0e-28	119	COG3300	MHYT domain, NO-binding membrane sensor	236
643774464	589	40.71	1	556	1	557	0.0e+00	478	COG0497	DNA repair ATPase RecN	557
643774465	289	39.08	1	280	1	281	2.0e-60	225	COG0061	NAD kinase	281
643774466	630	49.2	1	622	2	621	0.0e+00	781	COG1154	Deoxyxylulose-5-phosphate synthase	627
643774467	307	44.35	46	279	32	259	3.0e-51	195	COG0142	Geranylgeranyl pyrophosphate synthase	322
643774468	70	36.36	1	66	10	75	2.0e-06	44.2	COG1722	Exonuclease VII small subunit	81
643774469	396	44.89	9	330	2	324	2.0e-93	336	COG1570	Exonuclease VII, large subunit	440
643774470	294	56.51	4	294	1	281	2.0e-103	368	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
643774471	528	44.84	307	528	1	222	6.0e-41	162	COG1418	HD superfamily phosphodieaserase, includes HD domain of RNase Y	222
643774472	102	26.92	5	81	2	79	1.0e-05	41.4	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
643774474	812	33.33	144	810	2	650	6.0e-118	418	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
643774475	336	50.51	48	333	45	335	1.0e-96	346	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
643774476	124	60.68	1	117	1	117	1.0e-35	141	COG0292	Ribosomal protein L20	118
643774477	65	57.14	1	63	1	62	9.0e-08	48.7	COG0291	Ribosomal protein L35	65
643774478	186	59.76	18	186	5	173	4.0e-62	230	COG0290	Translation initiation factor IF-3	176
643774479	293	22.22	61	293	29	232	7.0e-13	68	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
643774481	214	39.02	1	205	4	208	1.0e-56	212	COG2344	NADH/NAD ratio-sensing transcriptional regulator Rex	211
643774482	303	43.68	27	286	4	258	1.0e-70	260	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
643774483	567	29.47	277	554	90	365	2.0e-39	157	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
643774485	110	27.18	9	110	12	114	6.0e-10	55.8	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
643774486	340	50.3	15	337	1	325	3.0e-80	292	COG0280	Phosphotransacetylase	327
643774487	188	57.42	27	181	5	159	1.0e-57	215	COG0669	Phosphopantetheine adenylyltransferase	159
643774488	173	42.08	1	170	2	184	2.0e-41	161	COG0742	16S rRNA G966 N2-methylase RsmD	187
643774489	599	40.58	67	513	9	448	7.0e-96	345	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
643774490	239	23.18	1	233	2	233	4.0e-11	61.9	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
643774491	657	34.18	5	473	1	459	1.0e-94	341	COG0358	DNA primase (bacterial type)	568
643774492	819	34.19	4	818	2	753	7.0e-116	412	COG1193	dsDNA-specific endonuclease/ATPase MutS2	753
643774493	150	36.49	6	148	1	148	6.0e-22	96.9	COG1610	Uncharacterized conserved protein YqeY	148
643774495	114	42.86	5	114	2	112	6.0e-27	112	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
643774496	240	29.17	2	233	8	246	1.0e-33	136	COG1385	16S rRNA U1498 N3-methylase RsmE	246
643774497	282	33.62	49	274	62	292	6.0e-41	161	COG2264	Ribosomal protein L11 methylase PrmA	300
643774498	377	44.15	3	376	5	370	4.0e-106	378	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
643774499	347	40.64	6	346	3	340	5.0e-72	265	COG1420	Transcriptional regulator of heat shock response	346
643774500	400	36.02	12	393	36	409	5.0e-91	328	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
643774501	348	37.14	5	342	3	348	7.0e-73	267	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
643774502	340	54.31	1	339	2	349	2.0e-121	429	COG0536	GTPase involved in cell partioning and DNA repair	369
643774504	371	40.43	39	364	11	339	2.0e-71	263	COG4448	L-asparaginase II	339
643774509	394	48.4	2	375	37	407	2.0e-106	379	COG2262	50S ribosomal subunit-associated GTPase HflX	411
643774510	167	23.48	17	143	7	138	4.0e-08	51.1	COG5608	LEA14-like dessication related protein	161
643774511	459	55.09	11	442	4	435	0.0e+00	578	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
643774513	446	33.5	16	426	12	406	9.0e-56	211	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
643774514	251	41.43	2	246	1	249	4.0e-43	168	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643774515	247	27.76	1	232	1	242	2.0e-25	109	COG4464	Tyrosine-protein phosphatase YwqE	254
643774517	928	47.12	1	924	6	879	0.0e+00	962	COG0013	Alanyl-tRNA synthetase	879
643774518	180	27.65	7	176	2	165	1.0e-11	63	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
643774519	341	64.18	5	282	6	279	3.0e-83	302	COG0468	RecA/RadA recombinase	279
643774520	121	37.07	5	119	1	113	1.0e-17	81.8	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
643774521	250	31.4	1	247	8	257	1.0e-35	143	COG0584	Glycerophosphoryl diester phosphodiesterase	257
643774524	248	39.72	23	236	20	221	2.0e-34	139	COG2045	Phosphosulfolactate phosphohydrolase or related enzyme	230
643774526	396	48.17	23	377	1	353	3.0e-116	411	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
643774527	167	35.85	7	165	1	140	3.0e-21	94.4	COG0511	Biotin carboxyl carrier protein	140
643774528	362	44.2	8	361	13	383	2.0e-77	283	COG0006	Xaa-Pro aminopeptidase	384
643774529	152	59.44	1	143	1	143	2.0e-50	191	COG0757	3-dehydroquinate dehydratase	146
643774532	86	33.33	4	81	2	79	8.0e-12	61.9	COG1826	Sec-independent protein translocase protein TatA	94
643774534	334	34.36	17	333	2	321	6.0e-58	217	COG0142	Geranylgeranyl pyrophosphate synthase	322
643774536	416	37.73	35	410	31	398	1.0e-66	247	COG1228	Imidazolonepropionase or related amidohydrolase	406
643774537	335	28.21	21	285	12	281	4.0e-27	115	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
643774538	562	67.63	10	562	5	557	0.0e+00	873	COG2987	Urocanate hydratase	561
643774539	505	54.71	1	498	3	498	0.0e+00	513	COG2986	Histidine ammonia-lyase	498
643774541	254	37.6	8	248	7	247	8.0e-43	167	COG0805	Sec-independent protein secretion pathway component TatC	255
643774542	285	28.44	67	285	47	262	2.0e-21	96.2	COG1729	Periplasmic TolA-binding protein (function unknown)	262
643774543	185	35.33	25	174	38	187	9.0e-27	113	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
643774544	420	27.79	48	415	46	423	6.0e-43	168	COG0823	Periplasmic component of the Tol biopolymer transport system	425
643774545	249	23.28	13	230	6	228	5.0e-06	45.1	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
643774546	137	36.5	1	136	1	137	3.0e-28	117	COG0848	Biopolymer transport protein ExbD	137
643774547	233	33.18	19	229	6	211	2.0e-30	125	COG0811	Biopolymer transport protein ExbB/TolQ	216
643774548	322	39.94	3	318	1	314	7.0e-55	207	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643774550	170	33.92	4	170	2	167	7.0e-31	126	COG0629	Single-stranded DNA-binding protein	167
643774551	152	34.84	1	138	17	171	6.0e-16	77	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
643774552	257	26.73	30	238	4	220	3.0e-19	89	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
643774554	159	42.45	18	156	6	142	6.0e-34	136	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
643774555	700	63.88	1	669	1	661	0.0e+00	1027	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
643774556	695	27.32	270	643	12	408	5.0e-31	130	COG0840	Methyl-accepting chemotaxis protein	408
643774557	717	46.7	17	709	23	700	0.0e+00	800	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
643774558	244	46.67	20	244	1	224	4.0e-58	218	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
643774559	501	26.74	29	496	2	449	3.0e-55	209	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
643774562	336	45.27	26	321	2	295	2.0e-68	252	COG1230	Co/Zn/Cd efflux system component	296
643774564	211	41.92	1	196	3	196	2.0e-44	172	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
643774565	287	25.64	5	236	7	238	2.0e-16	79.9	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
643774566	452	49.89	11	439	1	434	0.0e+00	521	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
643774567	370	41.16	3	370	1	373	5.0e-94	337	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
643774568	353	29.39	9	349	1	342	4.0e-52	198	COG0673	Predicted dehydrogenase	342
643774570	1094	69.4	13	414	1	400	0.0e+00	576	COG0458	Carbamoylphosphate synthase large subunit	400
643774571	331	26.51	10	329	3	338	3.0e-38	152	COG1089	GDP-D-mannose dehydratase	345
643774572	321	58.82	1	316	2	341	0.0e+00	479	COG1089	GDP-D-mannose dehydratase	345
643774573	73	38.24	6	67	3	70	8.0e-11	58.8	COG0227	Ribosomal protein L28	77
643774574	118	61.21	1	116	1	116	1.0e-36	145	COG0203	Ribosomal protein L17	116
643774575	357	41.56	9	328	1	310	8.0e-73	267	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
643774576	211	46.7	1	211	1	205	8.0e-54	203	COG0522	Ribosomal protein S4 or related protein	205
643774577	125	59.2	1	125	5	129	5.0e-41	159	COG0100	Ribosomal protein S11	129
643774578	125	59.5	1	121	1	121	3.0e-38	150	COG0099	Ribosomal protein S13	121
643774580	247	43.67	19	247	15	235	1.0e-45	176	COG0284	Orotidine-5'-phosphate decarboxylase	240
643774581	327	38.56	23	321	3	305	6.0e-67	247	COG0167	Dihydroorotate dehydrogenase	310
643774582	439	32.68	179	430	14	229	2.0e-36	146	COG0860	N-acetylmuramoyl-L-alanine amidase	231
643774583	156	62.76	12	156	7	151	8.0e-56	209	COG0691	tmRNA-binding protein	153
643774586	163	35.21	1	142	1	139	3.0e-28	117	COG1959	DNA-binding transcriptional regulator, IscR family	150
643774587	474	51.29	1	464	2	466	0.0e+00	580	COG1027	Aspartate ammonia-lyase	471
643774589	220	35.51	4	216	8	252	5.0e-25	108	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
643774590	343	45.34	9	319	6	303	5.0e-81	294	COG0492	Thioredoxin reductase	305
643774592	244	34.92	1	240	1	250	2.0e-29	123	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643774593	299	37.3	27	266	4	247	5.0e-35	141	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
643774596	440	40.46	2	434	1	397	1.0e-85	310	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
643774600	443	23.02	25	407	12	347	4.0e-37	149	COG1260	Myo-inositol-1-phosphate synthase	362
643774601	213	27.46	16	200	1	186	1.0e-13	70	COG0558	Phosphatidylglycerophosphate synthase	192
643774602	433	35.31	36	432	25	409	1.0e-82	301	COG3876	Uncharacterized conserved protein YbbC, DUF1343 family	409
643774603	389	31.72	16	375	11	375	1.0e-39	157	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643774604	109	53.7	1	108	4	109	7.0e-30	122	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
643774605	653	36.03	48	292	3	236	4.0e-49	189	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
643774606	511	25.21	5	474	1	467	1.0e-31	131	COG0591	Na+/proline symporter	493
643774607	316	33.55	8	314	3	295	2.0e-35	143	COG2971	BadF-type ATPase, related to human N-acetylglucosamine kinase	301
643774608	429	44.09	16	417	1	400	5.0e-88	318	COG1301	Na+/H+-dicarboxylate symporter	415
643774609	494	31.25	26	485	18	454	8.0e-44	171	COG0531	Amino acid transporter	466
643774611	135	30.08	1	133	1	131	4.0e-22	97.2	COG0848	Biopolymer transport protein ExbD	137
643774612	153	34.06	1	138	2	137	4.0e-20	91	COG0848	Biopolymer transport protein ExbD	137
643774613	241	29.25	6	214	1	209	5.0e-28	118	COG0811	Biopolymer transport protein ExbB/TolQ	216
643774614	240	19.91	19	239	31	244	1.0e-05	43.6	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
643774615	504	36.09	179	478	41	330	7.0e-43	168	COG0642	Signal transduction histidine kinase	336
643774616	222	48.02	1	221	1	226	2.0e-57	215	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643774617	459	43.48	11	456	6	463	9.0e-121	427	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643774619	156	29.5	19	150	7	145	7.0e-18	83.5	COG0071	Molecular chaperone IbpA, HSP20 family	146
643774620	159	37.18	6	155	1	153	1.0e-34	138	COG1225	Peroxiredoxin	157
643774626	625	21.17	3	520	1	479	1.0e-23	104	COG0591	Na+/proline symporter	493
643774627	399	44.22	11	395	8	391	7.0e-94	338	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
643774628	527	29.22	18	527	5	567	5.0e-71	262	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
643774629	383	29.88	59	381	10	311	8.0e-51	194	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
643774630	505	26.67	5	366	6	365	5.0e-39	155	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643774631	256	33.64	36	255	20	230	3.0e-25	109	COG1802	DNA-binding transcriptional regulator, GntR family	230
643774632	620	29.5	28	615	9	563	1.0e-81	297	COG2936	Predicted acyl esterase	563
643774633	270	30.38	2	258	4	252	3.0e-36	145	COG3375	Predicted acetyltransferase, GNAT superfamily	266
643774634	372	30.37	3	368	2	370	8.0e-58	218	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
643774635	439	28.38	1	438	5	451	6.0e-32	132	COG0531	Amino acid transporter	466
643774637	266	18.11	56	181	8	126	2.0e-06	46.5	COG2010	Cytochrome c, mono- and diheme variants	150
643774639	475	22.6	53	454	19	394	5.0e-20	92.7	COG5557	Ni/Fe-hydrogenase 2 integral membrane subunit HybB	401
643774640	1028	19.69	24	659	2	752	5.0e-43	170	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
643774643	301	25	85	285	85	292	3.0e-12	66.2	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
643774644	411	32.63	15	403	10	429	3.0e-63	236	COG0001	Glutamate-1-semialdehyde aminotransferase	432
643774645	283	36.1	9	248	5	238	1.0e-43	170	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
643774647	530	25.78	6	499	14	522	7.0e-60	225	COG0747	ABC-type transport system, periplasmic component	556
643774648	326	40.31	1	324	1	316	2.0e-73	269	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
643774649	309	45.11	19	283	22	280	2.0e-58	220	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
643774651	237	37.37	45	237	14	208	2.0e-29	122	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
643774652	201	60.59	1	200	2	200	9.0e-76	276	COG0605	Superoxide dismutase	204
643774655	652	51.08	2	649	14	652	0.0e+00	780	COG1166	Arginine decarboxylase (spermidine biosynthesis)	652
643774656	263	41.49	1	240	1	226	7.0e-51	194	COG2013	Uncharacterized conserved protein, AIM24 family	227
643774657	1003	20.33	431	954	101	614	9.0e-34	139	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
643774658	207	31.31	3	181	1	197	3.0e-25	108	COG2928	Uncharacterized membrane protein	222
643774661	414	28.61	7	414	2	402	1.0e-43	171	COG1228	Imidazolonepropionase or related amidohydrolase	406
643774664	577	24.87	24	565	38	598	5.0e-69	256	COG1164	Oligoendopeptidase F	598
643774665	809	46.45	46	497	1	462	3.0e-130	459	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643774666	317	32.69	49	307	6	228	7.0e-53	201	COG0274	Deoxyribose-phosphate aldolase	228
643774668	319	27.9	13	243	9	218	1.0e-27	117	COG0300	Short-chain dehydrogenase	265
643774669	459	33.26	8	456	37	483	1.0e-79	290	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
643774672	732	22.5	30	664	174	745	4.0e-41	163	COG4775	Outer membrane protein assembly factor BamA	766
643774676	446	24.06	86	423	25	388	5.0e-28	119	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643774678	146	28.79	1	132	2	133	1.0e-20	92.3	COG1959	DNA-binding transcriptional regulator, IscR family	150
643774679	153	43.15	15	152	5	149	8.0e-18	83.2	COG2165	Type II secretory pathway, pseudopilin PulG	149
643774684	318	25.9	182	318	3	134	2.0e-06	46.6	COG3976	Uncharacterized protein, contains FMN-binding domain	135
643774685	288	33.67	2	266	28	322	5.0e-50	191	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
643774686	283	23.32	17	258	14	319	1.0e-06	47.6	COG4658	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfD subunit	338
643774687	144	33.81	7	143	1	137	4.0e-24	104	COG0824	Acyl-CoA thioesterase FadM	137
643774689	556	68.56	10	556	6	552	0.0e+00	830	COG3573	Predicted oxidoreductase	552
643774693	439	39.18	4	439	3	427	3.0e-97	349	COG1253	Hemolysin or related protein, contains CBS domains	429
643774696	260	20.39	6	156	3	143	2.0e-09	56.8	COG5616	TolB amino-terminal domain (function unknown)	152
643774697	303	33.2	40	282	22	265	4.0e-60	225	COG2326	Polyphosphate kinase 2, PPK2 family	270
643774698	162	27.5	9	150	10	166	1.0e-12	66.2	COG3467	Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily	166
643774699	324	38.41	18	305	8	293	1.0e-55	210	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
643774700	312	38.18	16	306	13	304	2.0e-54	206	COG1560	Lauroyl/myristoyl acyltransferase	308
643774702	259	41.6	3	256	1	251	9.0e-43	167	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643774706	124	29.06	4	118	2	118	1.0e-11	62.2	COG3682	Predicted transcriptional regulator	123
643774707	509	21.07	43	356	11	337	2.0e-11	64.6	COG4219	Signal transducer regulating beta-lactamase production, contains  metallopeptidase domain	337
643774708	130	43.18	1	129	1	130	3.0e-22	97.4	COG3742	Uncharacterized protein, contains PIN domain	131
643774709	86	40.96	1	83	1	79	3.0e-08	50.3	COG4423	Uncharacterized protein	81
643774724	188	39.37	4	130	5	131	1.0e-30	126	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
643774725	223	29.76	23	204	8	212	2.0e-17	82.7	COG2755	Lysophospholipase L1 or related esterase	216
643774726	262	50.66	32	257	1	226	4.0e-79	288	COG1136	ABC-type lipoprotein export system, ATPase component	226
643774727	931	29.78	294	929	218	828	3.0e-83	304	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
643774730	314	22.68	4	292	2	297	6.0e-13	68.5	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643774732	137	45.83	9	128	1	120	2.0e-30	124	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
643774733	534	29.38	6	431	4	408	1.0e-60	227	COG1649	Uncharacterized lipoprotein YddW, UPF0748 family	418
643774734	400	37.14	12	388	8	391	2.0e-86	313	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
643774735	397	20.9	1	384	11	418	3.0e-50	192	COG3508	Homogentisate 1,2-dioxygenase	427
643774736	374	38.03	1	372	1	357	9.0e-74	270	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
643774737	126	25.23	20	122	41	147	4.0e-06	43.9	COG1555	DNA uptake protein ComE and related DNA-binding proteins	149
643774739	672	35.73	96	645	1	522	8.0e-120	424	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
643774741	510	26.75	32	493	8	468	3.0e-42	166	COG4145	Na+/panthothenate symporter	473
643774744	328	24.1	20	326	35	312	2.0e-25	110	COG1899	Deoxyhypusine synthase	318
643774747	312	38.66	1	307	1	311	6.0e-44	171	COG0657	Acetyl esterase/lipase	312
643774748	298	32.89	3	298	2	243	2.0e-38	153	COG3279	DNA-binding response regulator, LytR/AlgR family	244
643774751	248	35.44	13	244	10	233	6.0e-36	144	COG2859	Uncharacterized protein	237
643774753	245	39.67	1	231	3	242	5.0e-55	207	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
643774754	155	36.19	20	123	22	125	3.0e-13	68	COG0526	Thiol-disulfide isomerase or thioredoxin	127
643774755	447	31.07	169	447	40	300	8.0e-44	171	COG2813	16S rRNA G1207 methylase RsmC	300
643774758	611	62.19	1	603	3	602	0.0e+00	909	COG1217	Predicted membrane GTPase involved in stress response	603
643774759	309	40.18	11	304	5	329	6.0e-69	254	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
643774760	463	22.05	51	312	21	268	2.0e-11	64.4	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
643774762	1104	40.09	27	1102	8	1133	0.0e+00	981	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
643774766	598	64.21	1	598	4	601	0.0e+00	978	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
643774767	351	30.06	9	348	6	329	9.0e-45	174	COG0859	ADP-heptose:LPS heptosyltransferase	334
643774768	331	36.7	4	329	6	313	1.0e-56	213	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
643774769	340	21.45	10	338	4	305	3.0e-09	56.4	COG0524	Sugar or nucleoside kinase, ribokinase family	311
643774773	306	30.91	3	306	66	393	4.0e-44	171	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
643774774	232	56.22	1	217	2	218	3.0e-72	264	COG2884	ABC-type ATPase involved in cell division	223
643774775	286	30.41	1	285	6	297	7.0e-41	161	COG2177	Cell division protein FtsX	297
643774776	405	27.46	4	402	18	419	2.0e-37	150	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
643774777	293	38.21	14	288	4	273	1.0e-58	219	COG0648	Endonuclease IV	280
643774778	720	18.48	38	718	25	766	1.0e-27	118	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643774780	539	58.75	13	538	5	527	0.0e+00	749	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
643774784	421	37.11	1	341	3	346	1.0e-65	244	COG1078	HD superfamily phosphohydrolase	421
643774787	259	39.52	1	244	6	253	4.0e-57	214	COG0631	Serine/threonine protein phosphatase PrpC	262
643774788	645	38.86	35	630	2	566	2.0e-125	443	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
643774789	958	49.49	1	951	2	934	0.0e+00	1196	COG0178	Excinuclease UvrABC ATPase subunit	935
643774792	144	41.48	5	139	3	137	1.0e-26	112	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
643774796	489	20.93	135	469	116	444	1.0e-13	71.7	COG1538	Outer membrane protein TolC	457
643774797	398	34.76	70	386	43	361	1.0e-24	107	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643774798	1029	48.88	4	1028	5	1027	0.0e+00	1110	COG3696	Cu/Ag efflux pump CusA	1027
643774799	167	24.85	2	167	12	180	1.0e-21	95.8	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
643774800	71	60.56	1	71	2	72	5.0e-20	89.5	COG0361	Translation initiation factor IF-1	75
643774801	69	66.15	2	66	1	65	7.0e-24	102	COG1278	Cold shock protein, CspA family	67
643774802	192	45.25	10	188	3	174	5.0e-38	150	COG0431	NAD(P)H-dependent FMN reductase	184
643774803	391	28.65	51	391	3	312	2.0e-48	186	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
643774806	491	34.77	178	476	39	328	5.0e-38	152	COG0642	Signal transduction histidine kinase	336
643774809	296	40.93	69	294	1	233	1.0e-45	177	COG0412	Dienelactone hydrolase	236
643774810	437	36.71	30	386	2	350	1.0e-57	217	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
643774811	119	56.3	1	116	1	119	8.0e-26	109	COG3759	Uncharacterized membrane protein	121
643774818	635	30.51	43	635	15	562	1.0e-64	241	COG2936	Predicted acyl esterase	563
643774819	994	15.09	113	782	53	645	5.0e-11	64.2	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643774822	223	29.44	11	222	8	189	2.0e-13	69.3	COG3544	Uncharacterized conserved protein, DUF305 family	190
643774823	378	23.43	39	299	1	278	6.0e-21	95.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643774829	292	37.99	14	288	2	261	1.0e-39	157	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
643774830	464	28.23	9	459	1	451	3.0e-27	116	COG0531	Amino acid transporter	466
643774831	470	29.17	27	453	1	428	1.0e-68	254	COG0612	Predicted Zn-dependent peptidase	438
643774832	496	29.17	47	473	6	436	4.0e-65	242	COG0612	Predicted Zn-dependent peptidase	438
643774833	176	59.49	10	167	1	156	2.0e-50	191	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
643774834	404	44.32	16	374	1	358	6.0e-108	384	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
643774836	412	49.14	1	408	1	394	0.0e+00	493	COG0282	Acetate kinase	396
643774837	459	65.51	9	439	3	426	0.0e+00	622	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
643774838	719	38.35	35	352	17	368	1.0e-77	284	COG2021	Homoserine acetyltransferase	368
643774838	719	38.96	397	718	2	324	7.0e-66	245	COG0460	Homoserine dehydrogenase	333
643774839	390	36.74	31	383	1	347	3.0e-56	212	COG3191	L-aminopeptidase/D-esterase	348
643774841	163	56.49	5	158	1	153	3.0e-52	197	COG0315	Molybdenum cofactor biosynthesis enzyme	157
643774843	589	24.22	37	283	38	284	4.0e-10	60.2	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
643774845	223	49.06	11	222	1	211	5.0e-53	200	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643774847	541	29.46	271	527	48	301	3.0e-31	130	COG0668	Small-conductance mechanosensitive channel	316
643774864	683	24.92	38	637	28	597	3.0e-58	220	COG5525	Phage terminase, large subunit GpA	611
643774867	608	27.47	35	541	14	489	3.0e-34	140	COG5511	Bacteriophage capsid protein	492
643774868	502	26.42	74	316	59	299	1.0e-29	124	COG0616	Periplasmic serine protease, ClpP class	317
643774891	234	40.08	1	230	1	225	3.0e-44	171	COG2135	Putative SOS response-associated peptidase YedK	226
643774892	250	51.02	1	244	1	245	3.0e-76	278	COG4422	Bacteriophage protein gp37	250
643774903	581	24.42	41	250	5	209	1.0e-13	72.2	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
643774910	281	38.02	14	270	3	249	3.0e-41	162	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643774911	228	47.57	18	199	1	181	3.0e-48	185	COG0164	Ribonuclease HII	199
643774912	118	67.92	7	112	10	115	1.0e-37	148	COG0335	Ribosomal protein L19	115
643774913	689	40.18	23	683	1	648	0.0e+00	531	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
643774915	656	21.16	82	630	48	584	1.0e-17	85	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
643774916	632	41.15	1	530	1	527	0.0e+00	489	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
643774917	157	34.29	20	156	10	137	9.0e-12	63	COG3011	Predicted thiol-disulfide oxidoreductase YuxK, DCC family	137
643774918	502	33.73	11	496	7	475	5.0e-92	332	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
643774922	452	29.84	1	448	7	453	3.0e-57	216	COG0534	Na+-driven multidrug efflux pump	455
643774924	731	27.13	11	729	118	773	7.0e-68	252	COG4993	Glucose dehydrogenase	773
643774927	152	43.24	48	152	20	129	6.0e-23	99	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
643774929	657	30.05	35	210	36	215	1.0e-14	75.3	COG0666	Ankyrin repeat	235
643774936	462	19.5	47	441	2	366	2.0e-25	110	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643774938	1113	24.6	35	701	42	667	3.0e-53	204	COG4946	Uncharacterized N-terminal domain of tricorn protease	668
643774945	468	32.7	64	464	14	407	5.0e-128	451	COG0538	Isocitrate dehydrogenase	407
643774946	650	30.41	46	647	17	563	1.0e-83	304	COG2936	Predicted acyl esterase	563
643774948	293	48.85	2	215	1	217	6.0e-79	287	COG0336	tRNA G37 N-methylase TrmD	240
643774949	169	30.95	4	169	16	174	5.0e-25	107	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
643774950	104	56.32	2	87	1	87	4.0e-24	103	COG0228	Ribosomal protein S16	87
643774951	570	45.7	25	569	2	538	0.0e+00	538	COG0405	Gamma-glutamyltranspeptidase	539
643774955	272	32.2	11	270	2	244	2.0e-37	149	COG3279	DNA-binding response regulator, LytR/AlgR family	244
643774958	510	31.36	4	509	5	568	9.0e-67	248	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
643774959	546	30.84	12	541	5	568	3.0e-74	273	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
643774960	537	28.16	26	527	14	513	8.0e-66	245	COG0659	Sulfate permease or related transporter, MFS superfamily	554
643774961	257	38.97	1	192	1	195	1.0e-49	190	COG0288	Carbonic anhydrase	207
643774963	452	55.09	1	451	1	451	0.0e+00	555	COG0541	Signal recognition particle GTPase	451
643774964	835	46.5	17	786	8	774	0.0e+00	863	COG0466	ATP-dependent Lon protease, bacterial type	782
643774965	432	40.53	23	432	2	414	2.0e-90	326	COG2733	Uncharacterized membrane-anchored protein YjiN, DUF445 family	415
643774967	296	33.46	26	289	2	249	1.0e-22	100	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
643774968	265	38.62	13	253	13	254	3.0e-42	165	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
643774970	277	42.54	9	273	5	262	8.0e-60	224	COG0005	Purine nucleoside phosphorylase	262
643774971	357	39.58	9	336	5	335	4.0e-70	258	COG1816	Adenosine deaminase	345
643774973	1079	29.51	16	523	2	513	3.0e-75	277	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
643774974	223	48.34	2	212	7	217	4.0e-66	244	COG0572	Uridine kinase	218
643774975	239	48.26	10	235	2	229	2.0e-58	219	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643774976	479	29.48	34	465	2	447	6.0e-58	218	COG5002	Signal transduction histidine kinase	459
643774977	327	42.63	75	319	1	248	8.0e-65	240	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
643774978	918	18.18	327	917	189	767	3.0e-14	75	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643774981	389	33.71	24	371	10	318	2.0e-56	213	COG0226	ABC-type phosphate transport system, periplasmic component	318
643774982	307	50.5	7	300	18	308	1.0e-68	253	COG0573	ABC-type phosphate transport system, permease component	310
643774983	295	42.91	4	284	5	292	2.0e-56	213	COG0581	ABC-type phosphate transport system, permease component	292
643774984	265	51.95	10	265	5	253	3.0e-93	334	COG1117	ABC-type phosphate transport system, ATPase component	253
643774985	278	55.47	32	278	8	253	4.0e-100	357	COG1117	ABC-type phosphate transport system, ATPase component	253
643774986	235	41.28	6	223	7	224	5.0e-40	157	COG0704	Phosphate uptake regulator	240
643774987	530	37.86	12	465	4	451	1.0e-88	321	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
643774988	706	54.23	4	688	1	686	0.0e+00	863	COG0855	Polyphosphate kinase	696
643774989	345	35.63	1	343	1	326	5.0e-57	215	COG0306	Phosphate/sulfate permease	326
643774990	210	25.58	5	209	3	217	2.0e-21	96.1	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
643774991	256	33.92	77	247	60	220	2.0e-23	102	COG0705	Membrane associated serine protease, rhomboid family	228
643774992	645	61.32	2	605	4	579	0.0e+00	677	COG0443	Molecular chaperone DnaK (HSP70)	579
643774993	507	42.6	49	385	26	340	1.0e-61	231	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
643774994	299	46.77	31	292	2	264	1.0e-62	233	COG2362	D-aminopeptidase	274
643774997	593	35.61	16	413	30	449	9.0e-73	268	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
643774998	612	27.46	206	595	4	363	6.0e-47	182	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
643774999	351	34.93	32	255	16	237	2.0e-48	186	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
643775000	166	34.23	7	155	8	156	3.0e-32	131	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
643775001	520	50	91	507	1	418	0.0e+00	523	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
643775002	918	43.7	13	917	2	938	0.0e+00	1133	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
643775003	287	39.01	32	254	27	248	1.0e-49	190	COG1526	Formate dehydrogenase assembly factor FdhD	266
643775005	199	41.8	6	193	4	190	4.0e-41	161	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
643775006	545	31.94	44	541	1	428	2.0e-96	346	COG0281	Malic enzyme	432
643775007	463	35.24	17	460	14	464	6.0e-65	242	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
643775008	512	46.95	2	509	1	493	6.0e-128	451	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
643775009	631	45.12	5	626	1	606	1.0e-121	430	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
643775010	100	41	1	100	1	100	2.0e-14	70.5	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
643775011	169	29.68	2	156	7	161	4.0e-10	57.9	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
643775012	185	32.45	3	153	6	137	5.0e-24	104	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
643775013	384	38.12	3	381	2	331	9.0e-66	244	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
643775015	439	52.48	16	419	22	424	0.0e+00	493	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
643775016	158	45.33	7	156	9	156	1.0e-44	172	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
643775017	412	45.9	23	412	9	398	2.0e-123	435	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
643775018	174	46.51	27	155	21	148	5.0e-34	137	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
643775019	171	55.78	20	165	21	166	3.0e-52	197	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
643775020	122	29.66	1	118	4	119	2.0e-10	58.3	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
643775021	1007	21.66	119	761	37	556	7.0e-23	103	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
643775023	382	40.14	76	357	13	283	2.0e-49	189	COG1562	Phytoene/squalene synthetase	288
643775024	300	25.46	7	277	4	258	1.0e-20	93.9	COG2324	Uncharacterized membrane protein	281
643775025	487	31.9	1	484	4	479	1.0e-80	293	COG1233	Phytoene dehydrogenase-related protein	487
643775026	414	30.09	4	409	2	423	1.0e-64	240	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
643775027	204	61.81	5	203	3	200	2.0e-74	272	COG0740	ATP-dependent protease ClpP, protease subunit	200
643775028	420	65.29	10	420	1	406	0.0e+00	636	COG1219	ATP-dependent protease Clp, ATPase subunit	408
643775029	813	51.53	1	777	10	782	0.0e+00	952	COG0466	ATP-dependent Lon protease, bacterial type	782
643775030	204	47.46	20	193	20	196	1.0e-52	199	COG0218	GTP-binding protein EngB required for normal cell division	200
643775033	499	45.95	22	499	1	459	5.0e-129	454	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
643775034	525	32.35	286	523	1	220	7.0e-31	128	COG2114	Adenylate cyclase, class 3	227
643775036	365	27.81	22	353	3	332	6.0e-42	165	COG0859	ADP-heptose:LPS heptosyltransferase	334
643775037	207	56.45	15	198	4	189	6.0e-60	223	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
643775038	393	43.54	3	393	1	394	1.0e-120	426	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
643775039	150	54.17	1	144	1	144	2.0e-48	184	COG1490	D-Tyr-tRNAtyr deacylase	145
643775041	547	49.05	23	547	5	527	0.0e+00	687	COG4108	Peptide chain release factor RF-3	528
643775042	295	26.71	1	268	1	273	1.0e-33	136	COG0266	Formamidopyrimidine-DNA glycosylase	273
643775044	608	56.39	1	608	1	597	0.0e+00	790	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
643775045	456	35.2	11	448	13	455	1.0e-91	330	COG1109	Phosphomannomutase	464
643775047	358	39.35	8	338	13	350	7.0e-72	264	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
643775048	389	49.87	12	389	7	395	0.0e+00	471	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
643775049	361	21.72	2	267	28	302	2.0e-14	73.4	COG0501	Zn-dependent protease with chaperone function	302
643775050	426	49.41	1	424	1	425	0.0e+00	493	COG0151	Phosphoribosylamine-glycine ligase	428
643775051	279	38.71	1	278	1	272	4.0e-63	235	COG0266	Formamidopyrimidine-DNA glycosylase	273
643775053	171	28.99	5	163	1	169	3.0e-23	101	COG0622	Predicted phosphodiesterase	172
643775055	212	50.75	13	211	4	191	1.0e-62	232	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
643775056	318	30.28	30	311	16	288	1.0e-28	120	COG0382	4-hydroxybenzoate polyprenyltransferase	289
643775057	496	45.93	1	491	1	476	0.0e+00	524	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
643775058	258	40.43	31	256	9	235	6.0e-56	210	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
643775059	200	35.26	11	200	1	180	1.0e-29	122	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643775063	249	39.23	1	241	2	260	2.0e-55	209	COG1912	S-adenosylmethionine hydrolase (SAM-hydroxide adenosyltransferase)	268
643775064	436	32.57	9	436	18	450	3.0e-58	219	COG0534	Na+-driven multidrug efflux pump	455
643775065	387	38.99	88	352	1	265	2.0e-51	196	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
643775066	343	30.77	32	341	18	325	6.0e-47	181	COG0618	nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs	332
643775067	523	29.86	18	508	5	442	5.0e-40	159	COG0531	Amino acid transporter	466
643775068	496	32.27	268	486	1	170	3.0e-33	136	COG0516	IMP dehydrogenase/GMP reductase	170
643775069	184	26.8	57	151	13	106	4.0e-10	58	COG3339	Uncharacterized membrane protein YkvA, DUF1232 family	116
643775073	282	22.17	63	282	3	229	5.0e-13	68.7	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
643775075	520	52.75	5	510	2	506	0.0e+00	617	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
643775077	151	32.62	11	148	1	125	1.0e-15	75.8	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
643775078	545	31.29	66	536	24	464	4.0e-65	242	COG2027	D-alanyl-D-alanine carboxypeptidase	470
643775079	429	43.26	1	423	3	404	3.0e-87	315	COG0303	Molybdopterin biosynthesis enzyme	404
643775080	248	26.06	50	233	30	210	1.0e-12	66.9	COG3897	Predicted nicotinamide N-methyase	218
643775082	684	28.88	272	679	1	387	3.0e-65	243	COG0247	Fe-S oxidoreductase	388
643775083	329	44.92	2	325	1	313	1.0e-74	273	COG2025	Electron transfer flavoprotein, alpha subunit	313
643775084	251	45.21	1	251	1	260	4.0e-52	198	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
643775087	1032	16.57	112	773	33	618	2.0e-13	71.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643775088	402	37.4	19	402	1	393	1.0e-79	290	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643775091	230	31.09	30	218	21	199	4.0e-19	88.4	COG0400	Predicted esterase	207
643775092	380	39.13	4	130	1	138	4.0e-16	79.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
643775093	276	23.19	1	253	1	243	2.0e-15	76.5	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
643775094	337	47.99	1	336	2	345	5.0e-107	381	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
643775095	690	44.95	32	601	1	522	0.0e+00	513	COG1966	Carbon starvation protein CstA	575
643775096	71	34.38	9	71	2	65	3.0e-08	50.3	COG2879	Uncharacterized short protein YbdD, DUF466 family	65
643775097	801	24.54	217	793	48	618	5.0e-58	219	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
643775098	411	23.5	31	400	21	407	8.0e-21	95.2	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643775099	436	25.85	30	434	28	389	3.0e-25	109	COG0153	Galactokinase	390
643775100	269	23.88	6	269	3	242	2.0e-23	102	COG1209	dTDP-glucose pyrophosphorylase	286
643775102	329	27.61	1	328	2	342	1.0e-41	163	COG1208	NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins	358
643775103	125	29.46	12	118	22	127	3.0e-09	53.9	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
643775104	185	36.84	10	180	7	177	3.0e-32	131	COG0712	FoF1-type ATP synthase, delta subunit	178
643775105	166	32.69	8	163	6	161	9.0e-14	69.9	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
643775107	328	28.85	77	327	10	246	1.0e-31	130	COG0356	FoF1-type ATP synthase, membrane subunit a	246
643775111	328	42.5	15	325	10	319	3.0e-65	242	COG0714	MoxR-like ATPase	329
643775112	1093	20.05	277	952	1	699	8.0e-19	90.1	COG3899	Predicted ATPase	849
643775115	553	43.59	11	423	7	428	1.0e-99	357	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643775116	374	51.47	10	373	2	375	1.0e-112	399	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
643775117	155	51.61	1	155	2	156	5.0e-55	206	COG1225	Peroxiredoxin	157
643775118	303	56.86	1	299	5	310	6.0e-123	433	COG0078	Ornithine carbamoyltransferase	310
643775119	322	26.16	45	307	7	282	2.0e-16	79.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643775120	464	56.32	15	464	3	444	0.0e+00	577	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
643775122	181	63.79	5	178	1	174	4.0e-69	253	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
643775123	325	38.91	1	325	4	330	2.0e-71	263	COG1171	Threonine dehydratase	347
643775124	324	43.32	19	324	9	300	6.0e-77	281	COG4974	Site-specific recombinase XerD	300
643775125	461	55.26	12	454	2	437	0.0e+00	592	COG1206	Folate-dependent tRNA-U54 methylase TrmFO/GidA	439
643775126	816	47.09	50	625	1	553	0.0e+00	622	COG0550	DNA topoisomerase IA	570
643775128	183	37.13	12	177	4	168	6.0e-37	146	COG0703	Shikimate kinase	172
643775129	398	45.22	4	389	9	368	1.0e-111	396	COG0082	Chorismate synthase	369
643775133	206	23.83	14	206	26	206	2.0e-17	82.3	COG3167	Tfp pilus assembly protein PilO	211
643775135	404	31.92	60	404	4	354	3.0e-47	182	COG4972	Tfp pilus assembly protein, ATPase PilM	354
643775141	119	27.97	10	118	7	117	1.0e-07	48.5	COG4968	Tfp pilus assembly protein PilE	139
643775142	461	47.48	8	457	3	455	0.0e+00	485	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643775143	556	31.58	186	543	9	355	1.0e-42	168	COG3852	Signal transduction histidine kinase, nitrogen specific	363
643775144	433	38.48	3	431	7	428	2.0e-99	356	COG1253	Hemolysin or related protein, contains CBS domains	429
643775147	750	23.31	174	731	140	697	3.0e-61	230	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
643775148	460	21.15	36	346	28	276	3.0e-13	70.4	COG1566	Multidrug resistance efflux pump	352
643775149	482	19.92	3	474	8	443	3.0e-15	76.7	COG1538	Outer membrane protein TolC	457
643775150	177	34.38	22	174	1	148	7.0e-13	66.9	COG2954	CYTH domain, found in class IV adenylate cyclase and various triphosphatases	156
643775153	147	50	21	116	5	100	3.0e-21	94.6	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
643775155	122	43.2	1	122	8	129	9.0e-25	105	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
643775156	397	42.42	24	378	13	368	2.0e-72	266	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
643775157	156	50.64	1	156	1	155	3.0e-36	144	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
643775158	441	35.65	10	365	1	349	5.0e-61	228	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
643775161	426	37.91	239	418	2	181	1.0e-37	151	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
643775162	596	31.58	32	461	3	393	4.0e-63	236	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643775163	638	41.67	300	599	18	316	5.0e-61	229	COG0616	Periplasmic serine protease, ClpP class	317
643775165	732	19.25	8	731	6	768	3.0e-31	130	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643775167	488	29.06	11	196	22	211	5.0e-15	76	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
643775169	395	45.06	13	394	14	404	2.0e-104	373	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
643775170	296	32.88	1	292	1	291	3.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
643775171	524	36.66	33	512	7	473	2.0e-83	303	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
643775172	351	32.09	27	343	16	328	3.0e-45	176	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
643775173	329	22.04	10	319	33	314	1.0e-14	74.3	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
643775174	660	32.25	327	639	71	408	4.0e-30	126	COG0840	Methyl-accepting chemotaxis protein	408
643775177	167	41.55	16	157	4	144	4.0e-26	110	COG1522	DNA-binding transcriptional regulator, Lrp family	154
643775178	409	43.69	8	393	7	395	3.0e-99	355	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
643775181	278	32.49	3	277	2	244	1.0e-37	150	COG3279	DNA-binding response regulator, LytR/AlgR family	244
643775185	398	42.71	1	398	1	397	2.0e-106	379	COG1459	Type II secretory pathway, component PulF	397
643775186	388	53.11	7	360	1	353	0.0e+00	461	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
643775187	634	46.4	92	632	2	498	0.0e+00	542	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
643775190	362	24.72	9	362	4	363	3.0e-33	136	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
643775191	264	36.95	13	261	17	265	4.0e-40	158	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
643775192	295	25	5	250	4	257	2.0e-19	89.8	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
643775195	468	30.75	17	457	1	447	2.0e-32	133	COG0531	Amino acid transporter	466
643775197	326	32.17	7	311	16	322	1.0e-24	107	COG1612	Heme A synthase	323
643775198	307	48.43	22	306	19	300	3.0e-72	265	COG0109	Polyprenyltransferase (heme O synthase)	304
643775199	586	41.08	14	585	1	563	4.0e-130	459	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
643775201	393	31.93	7	377	14	368	4.0e-32	132	COG0006	Xaa-Pro aminopeptidase	384
643775203	273	26.46	11	265	14	241	4.0e-25	108	COG1836	Uncharacterized membrane protein	247
643775204	436	25.81	29	423	6	375	2.0e-33	137	COG0644	Dehydrogenase (flavoprotein)	396
643775205	156	42.04	7	156	9	164	2.0e-32	132	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
643775208	418	49.88	7	417	2	412	1.0e-121	430	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
643775209	178	53.22	5	174	2	171	3.0e-49	187	COG0221	Inorganic pyrophosphatase	171
643775210	325	61.47	1	325	4	330	0.0e+00	493	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
643775211	309	55.05	5	309	3	306	5.0e-89	320	COG0181	Porphobilinogen deaminase	307
643775212	259	36	7	253	1	245	9.0e-35	140	COG1587	Uroporphyrinogen-III synthase	248
643775214	242	31.4	31	236	62	267	9.0e-16	77.3	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
643775215	231	29.7	13	214	4	204	2.0e-22	99.5	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
643775216	243	41.2	8	218	4	219	6.0e-50	190	COG1131	ABC-type multidrug transport system, ATPase component	293
643775217	654	46.3	68	635	1	528	0.0e+00	671	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
643775220	368	20.3	48	304	1	258	1.0e-11	64.7	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
643775222	186	24.19	3	175	4	187	4.0e-09	54.6	COG0558	Phosphatidylglycerophosphate synthase	192
643775224	903	29.49	4	428	3	436	7.0e-61	229	COG0612	Predicted Zn-dependent peptidase	438
643775226	395	24.04	41	246	34	236	6.0e-14	72.3	COG3063	Tfp pilus assembly protein PilF	250
643775227	306	50.69	14	301	17	306	2.0e-75	275	COG2313	Pseudouridine-5'-phosphate glycosidase (pseudoU degradation)	310
643775230	1040	45.87	1	1022	2	1025	0.0e+00	1035	COG3696	Cu/Ag efflux pump CusA	1027
643775231	404	27.97	47	393	31	361	7.0e-15	75.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643775232	446	22.69	108	431	115	449	9.0e-18	85.2	COG1538	Outer membrane protein TolC	457
643775234	463	31.63	132	462	18	331	3.0e-40	159	COG0642	Signal transduction histidine kinase	336
643775235	226	48.03	1	223	1	228	9.0e-57	213	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643775236	379	32.64	17	287	3	285	7.0e-35	141	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
643775237	917	62.5	5	915	1	861	0.0e+00	1198	COG1048	Aconitase A	861
643775239	311	28.85	2	311	5	294	5.0e-40	158	COG1597	Diacylglycerol kinase family enzyme	301
643775241	191	32.19	31	169	2	140	2.0e-22	99.2	COG1225	Peroxiredoxin	157
643775242	510	31.51	1	509	3	422	2.0e-52	200	COG2379	Glycerate-2-kinase	422
643775243	283	24.87	40	228	3	188	8.0e-06	44.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643775244	307	35.1	5	303	3	274	1.0e-47	183	COG0388	Predicted amidohydrolase	274
643775245	368	39.13	20	362	16	346	3.0e-87	315	COG2957	Agmatine/peptidylarginine deiminase	346
643775247	193	39.78	2	179	1	181	1.0e-27	116	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643775253	245	48.39	1	245	7	254	2.0e-59	222	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
643775254	238	53.78	14	236	5	219	1.0e-70	259	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
643775255	212	33.19	1	212	2	212	6.0e-39	154	COG0602	Organic radical activating enzyme	212
643775256	360	27.62	49	344	58	368	7.0e-23	101	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643775257	1049	40.62	1	1030	2	1008	0.0e+00	859	COG0841	Multidrug efflux pump subunit AcrB	1009
643775258	479	28.28	47	479	26	447	5.0e-42	165	COG1538	Outer membrane protein TolC	457
643775263	688	28.28	39	676	1	616	2.0e-78	287	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
643775265	146	26.23	1	122	3	120	7.0e-08	49.8	COG5349	Uncharacterized conserved protein, DUF983 family	126
643775266	362	27.75	31	359	15	368	6.0e-52	198	COG2021	Homoserine acetyltransferase	368
643775267	506	25.4	58	410	2	368	1.0e-37	151	COG0515	Serine/threonine protein kinase	384
643775269	219	48.29	3	207	2	199	8.0e-51	193	COG3342	Uncharacterized conserved protein, Ntn-hydrolase superfamily	265
643775274	469	23.68	83	459	92	456	9.0e-22	98.7	COG1538	Outer membrane protein TolC	457
643775275	350	19.71	1	337	3	352	9.0e-15	74.8	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643775276	1072	28.82	17	1056	9	1008	0.0e+00	562	COG0841	Multidrug efflux pump subunit AcrB	1009
643775278	108	40.57	1	105	4	109	2.0e-08	51	COG0640	DNA-binding transcriptional regulator, ArsR family	110
643775279	143	31.47	3	142	2	142	9.0e-22	96.2	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
643775280	121	31.82	10	118	15	122	6.0e-08	49.5	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
643775282	762	22.6	152	748	21	617	3.0e-40	160	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
643775283	1174	21.61	748	1141	2	400	8.0e-27	116	COG1228	Imidazolonepropionase or related amidohydrolase	406
643775284	122	49.58	1	119	1	118	2.0e-23	101	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
643775285	263	26.77	10	261	5	252	3.0e-11	62.7	COG0730	Uncharacterized membrane protein YfcA	258
643775290	728	28.16	111	722	17	608	2.0e-59	224	COG4206	Outer membrane cobalamin receptor protein	608
643775292	426	36.59	34	425	28	409	1.0e-84	307	COG3876	Uncharacterized conserved protein YbbC, DUF1343 family	409
643775293	371	23.04	40	363	20	361	8.0e-08	51.6	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)	364
643775294	895	17.7	88	894	17	765	1.0e-21	98.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643775295	169	57.72	1	147	2	150	2.0e-53	201	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
643775296	741	22.79	59	741	36	728	1.0e-68	255	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
643775298	268	37.02	4	263	1	242	8.0e-40	157	COG3279	DNA-binding response regulator, LytR/AlgR family	244
643775299	229	25.74	1	228	1	218	7.0e-17	80.7	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
643775300	329	41.56	1	316	1	315	8.0e-87	313	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
643775301	304	31.68	4	302	2	297	1.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
643775304	178	41.21	14	177	18	182	3.0e-30	124	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
643775305	341	49.42	3	341	2	338	3.0e-112	398	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
643775307	185	23.56	1	177	3	193	8.0e-08	50.3	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
643775308	568	31.26	34	540	9	472	5.0e-87	315	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
643775311	495	23.16	36	483	3	410	3.0e-40	160	COG0415	Deoxyribodipyrimidine photolyase	461
643775312	325	41.3	6	322	3	324	8.0e-70	257	COG1171	Threonine dehydratase	347
643775314	314	41.81	7	303	6	291	3.0e-73	268	COG1234	Ribonuclease BN, tRNA processing enzyme	292
643775318	171	50.35	20	162	15	157	2.0e-40	158	COG1607	Acyl-CoA hydrolase	157
643775320	413	35.36	6	411	5	405	4.0e-83	302	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
643775321	310	43.45	3	292	2	286	2.0e-67	248	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
643775323	470	41.15	35	469	29	451	2.0e-102	366	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
643775325	336	31.49	3	335	2	313	1.0e-48	187	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643775326	499	55.37	1	419	1	414	0.0e+00	573	COG1004	UDP-glucose 6-dehydrogenase	414
643775328	241	22.63	2	240	7	245	1.0e-15	76.9	COG3346	Cytochrome oxidase assembly protein ShyY1	252
643775329	871	53.31	119	744	1	628	0.0e+00	718	COG0296	1,4-alpha-glucan branching enzyme	628
643775331	252	48.67	13	162	4	152	1.0e-40	160	COG1321	Mn-dependent transcriptional regulator, DtxR family	154
643775332	150	25.17	1	141	4	154	1.0e-10	59.2	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
643775333	443	52.07	30	438	12	412	2.0e-95	343	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
643775334	587	34.62	35	586	11	538	2.0e-102	366	COG0405	Gamma-glutamyltranspeptidase	539
643775335	205	27.73	44	162	10	123	3.0e-07	48.5	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
643775336	118	31.13	14	117	2	107	2.0e-13	68	COG0607	Rhodanese-related sulfurtransferase	110
643775337	312	40.85	7	302	4	305	1.0e-73	270	COG1619	Muramoyltetrapeptide carboxypeptidase LdcA (peptidoglycan recycling)	313
643775338	302	37.63	21	300	1	284	5.0e-59	221	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
643775341	219	36.15	9	216	6	218	9.0e-33	133	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
643775342	173	34.68	8	173	5	177	4.0e-28	117	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643775344	304	20.22	37	298	52	315	2.0e-09	56.6	COG3595	Uncharacterized conserved protein YvlB, contains  DUF4097 and DUF4098 domains	318
643775346	226	60.18	1	225	3	228	5.0e-85	307	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
643775347	704	34.97	36	704	48	750	0.0e+00	494	COG4774	Outer membrane receptor for monomeric catechols	750
643775348	99	47.37	5	97	2	96	1.0e-24	104	COG2154	Pterin-4a-carbinolamine dehydratase	101
643775349	371	32.14	36	343	13	292	3.0e-43	169	COG1533	DNA repair photolyase	297
643775352	1113	35.01	29	1109	4	1070	0.0e+00	899	COG0587	DNA polymerase III, alpha subunit	1139
643775353	384	27.27	8	384	5	405	8.0e-58	217	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
643775354	157	38.66	37	155	25	143	6.0e-11	60.4	COG3753	Uncharacterized conserved protein YidB, DUF937 family	143
643775356	868	21.92	289	860	67	620	2.0e-25	111	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
643775358	70	64.18	2	68	1	67	1.0e-23	101	COG1278	Cold shock protein, CspA family	67
643775366	490	26.96	110	487	5	405	2.0e-54	207	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
643775368	893	18.15	149	893	44	768	2.0e-14	75	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643775369	366	32.16	75	355	41	318	4.0e-29	122	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
643775370	182	37.36	2	180	1	182	6.0e-23	100	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643775374	770	37.29	1	293	1	285	1.0e-59	225	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
643775375	387	42.16	1	386	1	391	2.0e-80	293	COG0183	Acetyl-CoA acetyltransferase	392
643775376	519	26.54	34	470	17	473	3.0e-39	156	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
643775377	437	27.64	70	437	1	293	8.0e-56	211	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
643775378	302	28.48	1	149	4	154	1.0e-13	70.4	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
643775379	183	41.52	6	176	2	171	3.0e-36	145	COG1986	Non-canonical (house-cleaning) NTP pyrophosphatase, all-alpha NTP-PPase family	175
643775380	207	29.24	38	206	28	193	4.0e-14	71.7	COG5516	Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding	196
643775387	359	42.05	1	359	3	346	1.0e-79	290	COG0205	6-phosphofructokinase	347
643775389	374	48.68	1	372	29	408	2.0e-113	402	COG0513	Superfamily II DNA and RNA helicase	513
643775392	284	30.69	2	284	1	281	1.0e-18	87.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643775394	703	31.93	40	305	2	283	8.0e-46	179	COG0515	Serine/threonine protein kinase	384
643775395	686	34.16	9	273	2	279	8.0e-49	188	COG0515	Serine/threonine protein kinase	384
643775396	847	47.93	3	843	6	782	0.0e+00	910	COG0466	ATP-dependent Lon protease, bacterial type	782
643775399	775	15.75	42	775	24	768	2.0e-25	111	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643775402	396	40.74	11	331	6	319	1.0e-95	343	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
643775403	699	36.31	4	672	8	638	2.0e-126	446	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
643775404	641	40.07	375	633	1	265	4.0e-63	236	COG0171	NH3-dependent NAD+ synthetase	268
643775405	238	43.23	7	233	2	229	6.0e-54	204	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643775408	460	23.33	38	453	23	443	6.0e-20	92.5	COG1538	Outer membrane protein TolC	457
643775409	328	24.82	53	323	95	361	8.0e-08	51.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643775410	1051	42.95	1	1031	1	1023	0.0e+00	969	COG3696	Cu/Ag efflux pump CusA	1027
643775411	263	32.16	14	256	2	249	1.0e-27	116	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
643775412	289	50.34	1	287	1	292	5.0e-86	311	COG2321	Predicted metalloprotease	295
643775415	165	37.12	15	146	3	133	5.0e-29	120	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
643775416	714	50.3	377	714	2	324	1.0e-115	411	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
643775418	988	21.74	461	955	144	620	4.0e-36	147	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
643775420	205	41.26	1	205	2	205	6.0e-43	167	COG0522	Ribosomal protein S4 or related protein	205
643775423	570	39.92	48	570	7	534	2.0e-127	449	COG1574	Predicted amidohydrolase YtcJ	535
643775424	214	32.02	5	204	21	223	1.0e-21	96.5	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
643775425	285	18.75	63	284	6	243	7.0e-07	48.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
643775426	510	28.88	67	293	21	251	8.0e-25	108	COG4242	Cyanophycinase and related exopeptidases	293
643775428	279	34.64	8	279	34	298	4.0e-36	145	COG0501	Zn-dependent protease with chaperone function	302
643775429	117	44.26	55	115	2	62	5.0e-14	70	COG3411	(2Fe-2S) ferredoxin	64
643775432	301	34.59	20	299	6	284	8.0e-67	247	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
643775433	152	33.33	19	152	1	137	3.0e-20	91.2	COG1765	Uncharacterized OsmC-related protein	137
643775434	472	22.78	80	461	17	373	3.0e-15	76.7	COG0006	Xaa-Pro aminopeptidase	384
643775438	204	36.93	2	172	1	176	4.0e-28	117	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643775441	82	44.3	4	81	2	68	2.0e-18	84.2	COG0254	Ribosomal protein L31	75
643775442	269	25	42	269	43	288	3.0e-09	55.7	COG1276	Putative copper export protein	289
643775443	136	29.46	5	133	2	125	8.0e-13	66.1	COG2372	Copper-binding protein CopC (methionine-rich)	127
643775444	422	29.17	37	401	2	364	8.0e-53	201	COG1858	Cytochrome c peroxidase	364
643775450	408	42.33	10	354	1	321	6.0e-87	314	COG0523	GTPase, G3E family	323
643775451	51	44	3	51	1	50	7.0e-07	45.6	COG0267	Ribosomal protein L33	50
643775452	319	24.54	2	313	1	323	2.0e-26	113	COG0523	GTPase, G3E family	323
643775455	124	33.87	3	123	18	141	2.0e-23	101	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
643775456	201	32.02	6	201	2	204	4.0e-33	134	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
643775457	152	37.29	36	152	26	143	7.0e-19	86.9	COG2847	Copper(I)-binding protein	151
643775459	388	48.05	3	385	5	388	3.0e-112	398	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
643775460	453	42.32	20	444	1	448	1.0e-123	437	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
643775461	248	34.48	6	237	4	220	2.0e-43	169	COG0132	Dethiobiotin synthetase	223
643775462	355	41.72	17	327	10	321	5.0e-86	311	COG0502	Biotin synthase or related enzyme	335
643775463	219	35.68	7	219	6	215	1.0e-42	166	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
643775464	211	56.4	2	211	4	214	2.0e-77	281	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
643775469	168	27.12	14	166	1	176	7.0e-15	73.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643775470	307	40.91	1	303	1	292	3.0e-79	288	COG1162	Putative ribosome biogenesis GTPase RsgA	301
643775472	309	29.34	1	297	8	321	4.0e-42	165	COG0506	Proline dehydrogenase	391
643775475	737	42.91	340	623	1	289	3.0e-76	280	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
643775476	431	37.61	7	430	1	391	8.0e-63	234	COG0183	Acetyl-CoA acetyltransferase	392
643775477	547	38.99	8	535	1	525	1.0e-111	397	COG0578	Glycerol-3-phosphate dehydrogenase	532
643775478	326	30.89	17	324	15	324	2.0e-49	189	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
643775479	161	35.42	14	150	7	149	8.0e-17	80	COG0782	Transcription elongation factor, GreA/GreB family	151
643775480	250	40.54	62	243	18	202	4.0e-46	178	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
643775482	108	33.01	1	99	5	101	2.0e-08	50.8	COG1694	NTP pyrophosphatase, house-cleaning of non-canonical NTPs	102
643775483	285	26.37	5	273	12	278	2.0e-27	116	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
643775485	1028	32.46	426	765	8	336	1.0e-41	165	COG0642	Signal transduction histidine kinase	336
643775487	364	44.25	21	357	2	337	6.0e-75	274	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
643775488	142	36.19	11	114	3	106	4.0e-18	84	COG0789	DNA-binding transcriptional regulator, MerR family	124
643775490	253	22.29	17	189	10	184	3.0e-06	45.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643775491	1068	37.68	15	1034	1	1009	0.0e+00	869	COG0841	Multidrug efflux pump subunit AcrB	1009
643775492	405	28.15	7	372	1	369	1.0e-13	71.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643775493	516	26.46	44	504	30	443	2.0e-28	121	COG1538	Outer membrane protein TolC	457
643775494	211	24.86	12	192	2	182	2.0e-09	56.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643775497	590	62.71	1	421	1	407	2.0e-125	443	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
643775498	231	43.04	1	224	1	229	1.0e-53	203	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643775499	512	31.25	172	505	21	334	2.0e-41	163	COG0642	Signal transduction histidine kinase	336
643775500	434	26.37	35	431	50	443	9.0e-10	58.6	COG1538	Outer membrane protein TolC	457
643775502	1041	36.69	1	1032	2	1021	0.0e+00	747	COG3696	Cu/Ag efflux pump CusA	1027
643775503	276	30.65	12	271	8	254	7.0e-39	154	COG0725	ABC-type molybdate transport system, periplasmic component	258
643775504	231	52.61	10	220	8	218	9.0e-57	213	COG4149	ABC-type molybdate transport system, permease component	225
643775506	233	43.42	8	233	3	229	1.0e-54	206	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643775510	688	68.85	8	688	7	681	0.0e+00	966	COG2216	High-affinity K+ transport system, ATPase chain B	681
643775511	199	60	1	188	1	190	2.0e-61	228	COG2156	K+-transporting ATPase, c chain	190
643775514	259	39.82	35	257	2	227	3.0e-31	128	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
643775518	485	48.72	14	481	1	466	0.0e+00	518	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643775519	377	43.47	4	377	2	366	3.0e-114	405	COG1062	Zn-dependent alcohol dehydrogenase	366
643775521	92	42.35	1	85	1	83	5.0e-15	73	COG1937	DNA-binding transcriptional regulator, FrmR family	89
643775522	787	45.1	1	783	1	709	0.0e+00	710	COG2217	Cation transport ATPase	713
643775523	69	42.25	1	69	1	71	3.0e-11	60.4	COG2608	Copper chaperone CopZ	71
643775524	308	43.07	30	301	3	263	6.0e-63	234	COG2514	Catechol-2,3-dioxygenase	265
643775529	204	27.98	12	204	2	187	3.0e-17	82	COG3544	Uncharacterized conserved protein, DUF305 family	190
643775531	357	27.93	18	337	7	336	3.0e-41	162	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
643775532	425	31.91	65	350	2	273	1.0e-36	147	COG0515	Serine/threonine protein kinase	384
643775536	438	42.58	34	436	3	397	8.0e-88	317	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
643775537	166	53.25	1	152	2	155	1.0e-52	199	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
643775538	759	23.19	47	758	26	727	1.0e-68	254	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
643775539	541	38.3	1	498	4	497	0.0e+00	521	COG0033	Phosphoglucomutase	524
643775548	321	27.27	1	151	1	149	4.0e-20	92.4	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
643775549	120	39.39	3	99	13	109	2.0e-11	61.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
643775550	173	20.71	21	151	12	150	1.0e-06	46.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
643775551	826	26.7	271	780	6	514	4.0e-43	170	COG2936	Predicted acyl esterase	563
643775555	161	28	24	147	38	149	2.0e-06	45.3	COG2010	Cytochrome c, mono- and diheme variants	150
643775556	353	27.18	2	202	1	204	2.0e-23	103	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
643775557	286	31.36	57	275	46	260	1.0e-19	90.8	COG3336	Cytochrome c oxidase assembly factor CtaG	299
643775560	563	43.67	16	558	43	585	0.0e+00	483	COG4425	Uncharacterized membrane protein	588
643775561	322	38.58	2	322	9	328	5.0e-65	241	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
643775565	916	17.33	184	878	6	736	6.0e-09	56.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643775566	335	34.37	18	334	23	321	6.0e-27	115	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
643775567	197	32.57	20	194	6	175	5.0e-24	104	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643775569	770	25.98	39	237	25	225	4.0e-13	70.7	COG3629	DNA-binding transcriptional activator of the SARP family	280
643775570	1114	13.74	189	893	27	658	3.0e-08	54.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643775572	634	28.83	7	386	4	381	4.0e-43	170	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643775573	276	35.29	6	276	2	242	2.0e-38	153	COG3279	DNA-binding response regulator, LytR/AlgR family	244
643775578	298	31.67	2	297	1	292	4.0e-25	108	COG0583	DNA-binding transcriptional regulator, LysR family	297
643775579	191	35.54	4	165	17	182	1.0e-28	119	COG2320	GrpB domain, predicted nucleotidyltransferase, UPF0157 family	185
643775582	293	28.62	6	289	1	282	4.0e-20	92.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643775583	361	37.3	35	340	7	313	2.0e-79	289	COG0180	Tryptophanyl-tRNA synthetase	314
643775587	200	26.67	24	186	24	182	3.0e-08	52	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643775588	765	30.27	111	381	2	282	6.0e-38	153	COG0515	Serine/threonine protein kinase	384
643775589	219	35.81	6	219	52	280	3.0e-35	141	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
643775590	110	32	5	104	2	101	5.0e-13	66.4	COG1695	DNA-binding transcriptional regulator, PadR family	138
643775591	898	19.34	512	898	1	419	2.0e-13	72.1	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
643775592	291	34.94	1	161	12	177	4.0e-20	92.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643775593	154	38.52	15	147	43	177	1.0e-18	86	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
643775595	332	28.7	28	239	2	203	2.0e-19	90.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643775596	209	24.38	23	181	2	161	1.0e-05	43.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643775597	599	24.22	13	378	4	380	1.0e-32	135	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643775604	925	27.85	100	305	25	237	1.0e-14	76.1	COG3629	DNA-binding transcriptional activator of the SARP family	280
643775608	502	33.33	78	502	19	447	2.0e-53	203	COG1538	Outer membrane protein TolC	457
643775609	1054	46.4	8	1033	5	1009	0.0e+00	919	COG0841	Multidrug efflux pump subunit AcrB	1009
643775610	380	30.87	1	375	5	372	3.0e-23	102	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643775611	201	29.78	9	184	5	182	2.0e-08	52.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643775612	361	35.69	81	349	3	281	1.0e-36	147	COG1408	Predicted phosphohydrolase, MPP superfamily	284
643775614	445	16.97	16	443	20	503	1.0e-39	157	COG3202	ATP/ADP translocase	509
643775615	319	28.67	35	291	3	290	4.0e-26	112	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
643775618	525	46.21	16	525	4	521	0.0e+00	525	COG3540	Phosphodiesterase/alkaline phosphatase D	522
643775619	190	27.22	8	185	3	176	3.0e-07	48.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643775620	1188	33.22	101	373	2	295	1.0e-44	176	COG0515	Serine/threonine protein kinase	384
643775624	290	32.32	22	283	12	248	5.0e-37	148	COG0631	Serine/threonine protein phosphatase PrpC	262
643775625	127	61.26	1	111	4	114	5.0e-42	163	COG3564	Uncharacterized conserved protein, DUF779 family	116
643775626	517	45.49	30	512	1	472	0.0e+00	493	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643775629	320	25.93	29	317	1	282	9.0e-14	71.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643775633	192	32.2	6	176	1	177	2.0e-26	112	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643775634	489	32.01	5	368	1	371	3.0e-42	166	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643775635	98	43	1	98	11	110	8.0e-21	91.9	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
643775636	182	29.14	10	157	4	151	1.0e-08	53.3	COG0597	Lipoprotein signal peptidase	167
643775637	388	34.42	9	375	1	359	8.0e-59	221	COG0349	Ribonuclease D	361
643775639	266	33.8	1	264	3	282	2.0e-26	113	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643775642	99	40	1	95	2	96	1.0e-18	84.8	COG1534	RNA-binding protein YhbY	97
643775645	221	37.37	14	207	12	209	7.0e-33	133	COG2345	Predicted transcriptional regulator, ArsR family	218
643775646	477	41.83	34	475	1	412	7.0e-119	420	COG0719	Fe-S cluster assembly scaffold protein SufB	412
643775647	249	61.94	1	246	3	245	3.0e-101	361	COG0396	Fe-S cluster assembly ATPase SufC	251
643775648	438	28.88	17	425	9	405	8.0e-72	264	COG0719	Fe-S cluster assembly scaffold protein SufB	412
643775649	160	41.22	2	148	1	148	2.0e-33	135	COG0822	NifU homolog involved in Fe-S cluster formation	150
643775650	103	40.86	6	98	11	103	2.0e-17	80.8	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
643775651	407	50.74	1	400	2	403	1.0e-124	440	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
643775652	148	33.33	13	148	6	143	4.0e-25	107	COG0822	NifU homolog involved in Fe-S cluster formation	150
643775656	97	29.67	1	89	2	92	2.0e-09	54.1	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
643775658	270	22.17	53	270	47	259	6.0e-07	48.2	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
643775659	303	35.55	1	291	2	293	8.0e-62	231	COG1131	ABC-type multidrug transport system, ATPase component	293
643775660	190	24.07	8	168	2	158	5.0e-09	54.5	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
643775661	202	28.65	12	196	3	193	5.0e-24	104	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
643775662	405	47.21	6	399	1	362	4.0e-120	425	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
643775663	245	43.98	5	244	4	238	2.0e-42	165	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
643775664	289	18.84	36	231	23	227	1.0e-09	57.6	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
643775667	842	30.41	50	821	28	753	5.0e-85	309	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
643775668	218	36.53	37	198	13	171	2.0e-16	79.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643775669	642	26.2	244	630	8	399	1.0e-33	138	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
643775671	688	29.86	210	543	7	336	8.0e-35	142	COG0642	Signal transduction histidine kinase	336
643775672	321	43.65	4	310	1	297	3.0e-86	311	COG4152	ABC-type uncharacterized transport system, ATPase component	300
643775673	429	22.27	4	419	2	398	2.0e-23	103	COG1668	ABC-type Na+ efflux pump, permease component	407
643775674	606	33.22	22	288	1	286	8.0e-45	175	COG0515	Serine/threonine protein kinase	384
643775675	565	19.92	69	527	2	428	3.0e-10	60.3	COG1232	Protoporphyrinogen oxidase	444
643775676	498	47.99	4	494	11	508	0.0e+00	492	COG4262	Predicted spermidine synthase with an N-terminal membrane domain	508
643775681	131	28.95	6	119	13	115	6.0e-13	66.5	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
643775682	337	34.2	1	337	1	345	8.0e-73	267	COG4260	Membrane protease subunit, stomatin/prohibitin family, contains C-terminal Zn-ribbon domain	345
643775684	128	33.64	11	120	7	96	9.0e-10	55.9	COG0234	Co-chaperonin GroES (HSP10)	96
643775685	498	19.75	160	482	66	369	1.0e-11	65.1	COG0006	Xaa-Pro aminopeptidase	384
643775687	333	23.19	1	330	1	311	7.0e-29	121	COG0627	S-formylglutathione hydrolase FrmB	316
643775688	266	23.08	35	149	10	165	6.0e-13	68.1	COG0681	Signal peptidase I	166
643775690	299	35.19	1	267	1	259	4.0e-44	171	COG0648	Endonuclease IV	280
643775692	544	33.4	51	534	5	472	6.0e-86	311	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643775693	313	40.19	1	311	1	291	1.0e-58	220	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
643775694	422	45.05	222	403	1	181	6.0e-38	152	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
643775697	240	49.55	12	231	1	222	2.0e-78	285	COG1136	ABC-type lipoprotein export system, ATPase component	226
643775699	835	18.53	19	432	13	417	1.0e-13	72.5	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
643775700	1550	55.21	730	1214	6	481	0.0e+00	574	COG0069	Glutamate synthase domain 2	485
643775703	586	25.87	89	365	12	289	4.0e-39	156	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
643775704	446	47.22	45	437	8	389	5.0e-107	381	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
643775705	441	29.95	80	440	32	405	8.0e-51	194	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
643775706	494	28.54	32	477	2	439	4.0e-74	272	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
643775707	694	27.38	303	559	93	335	9.0e-29	122	COG0642	Signal transduction histidine kinase	336
643775708	231	24.46	24	203	25	208	1.0e-16	79.9	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
643775709	1054	33.82	3	1022	2	1007	0.0e+00	815	COG0841	Multidrug efflux pump subunit AcrB	1009
643775711	505	21.22	3	478	1	438	2.0e-22	101	COG1538	Outer membrane protein TolC	457
643775712	218	19.07	3	194	11	201	2.0e-06	46.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643775716	776	28.44	396	590	60	252	1.0e-10	62.3	COG5426	Uncharacterized membrane protein	254
643775720	350	45.15	27	347	10	329	1.0e-63	236	COG0714	MoxR-like ATPase	329
643775726	514	38.98	1	514	3	522	3.0e-121	429	COG3540	Phosphodiesterase/alkaline phosphatase D	522
643775727	611	52.81	1	409	1	390	6.0e-105	375	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
643775729	317	50.63	1	315	2	312	1.0e-79	290	COG3817	Uncharacterized membrane protein	313
643775730	238	61.5	1	226	3	228	4.0e-75	274	COG3819	Uncharacterized membrane protein	229
643775731	251	34.78	9	118	1	115	6.0e-19	88.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
643775732	431	48.23	34	425	11	389	9.0e-109	387	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
643775733	308	23.92	11	307	14	282	6.0e-31	128	COG3016	Uncharacterized iron-regulated protein	295
643775737	353	44.86	1	347	1	339	1.0e-109	389	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
643775740	284	19.7	16	263	5	265	7.0e-13	68.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
643775741	240	43.17	15	239	3	228	9.0e-51	193	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643775743	115	28.83	1	109	4	112	1.0e-11	61.4	COG3795	Uncharacterized conserved protein	123
643775744	414	42.04	8	406	11	409	4.0e-68	252	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
643775745	389	39.67	21	381	23	388	7.0e-91	327	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
643775747	383	51.86	23	370	5	352	2.0e-117	415	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
643775748	285	33.68	1	267	1	284	5.0e-49	188	COG3781	Predicted membrane chloride channel, bestrophin family	306
643775749	241	43.97	128	241	14	129	5.0e-24	104	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
643775750	562	23.62	3	556	2	536	3.0e-72	266	COG2303	Choline dehydrogenase or related flavoprotein	542
643775752	167	21.64	4	165	3	172	7.0e-18	83.5	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
643775753	402	37.47	2	401	5	399	1.0e-73	270	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
643775754	311	32.88	1	278	4	294	3.0e-59	222	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
643775756	496	33.33	171	492	19	328	2.0e-42	166	COG0642	Signal transduction histidine kinase	336
643775757	226	46.72	1	223	1	228	1.0e-54	206	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643775759	939	48.07	397	939	5	538	0.0e+00	490	COG2898	Lysylphosphatidylglycerol synthetase, C-terminal domain, DUF2156 family	538
643775760	1375	33.95	717	1128	12	439	7.0e-51	197	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
643775766	736	23.01	2	734	1	768	2.0e-86	313	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
643775767	192	38.5	1	177	2	186	6.0e-31	127	COG0742	16S rRNA G966 N2-methylase RsmD	187
643775768	129	36.72	1	128	3	127	9.0e-27	112	COG2346	Truncated hemoglobin YjbI	133
643775772	524	29.12	40	474	26	473	1.0e-95	344	COG0069	Glutamate synthase domain 2	485
643775776	466	23.09	1	454	1	387	4.0e-21	96.5	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643775778	187	33.72	10	181	5	176	5.0e-30	124	COG3797	Uncharacterized conserved protein, DUF1697 family	178
643775780	345	37.46	1	345	4	337	6.0e-70	257	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
643775781	148	34.62	12	141	9	132	3.0e-19	87.8	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
643775783	157	22.22	1	153	4	141	3.0e-17	81.5	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
643775784	206	25	45	168	14	126	5.0e-06	44.5	COG0526	Thiol-disulfide isomerase or thioredoxin	127
643775786	394	51.41	9	388	7	396	1.0e-124	439	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
643775787	686	35.33	356	664	75	408	4.0e-34	140	COG0840	Methyl-accepting chemotaxis protein	408
643775788	379	46.15	4	326	1	323	1.0e-91	330	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
643775789	423	22.46	108	419	1	328	6.0e-25	109	COG0642	Signal transduction histidine kinase	336
643775791	960	20.49	79	752	8	584	7.0e-19	90	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
643775793	542	36.31	4	541	1	522	3.0e-118	419	COG3540	Phosphodiesterase/alkaline phosphatase D	522
643775794	579	30.18	99	575	148	695	3.0e-68	253	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
643775795	1210	29.65	1	1178	1	1139	0.0e+00	526	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
643775796	1101	28.36	31	1087	28	1075	0.0e+00	542	COG1330	Exonuclease V gamma subunit	1078
643775797	416	21.79	26	408	14	403	1.0e-33	137	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643775798	247	40.73	1	245	3	250	1.0e-64	240	COG0024	Methionine aminopeptidase	255
643775800	534	35.36	7	426	11	421	4.0e-57	216	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
643775801	356	44.2	1	354	3	352	1.0e-106	379	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
643775803	164	50	10	162	2	152	3.0e-47	180	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
643775805	579	29.11	28	381	3	369	5.0e-35	142	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643775806	256	39.69	1	252	1	250	7.0e-35	141	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643775807	301	41.72	4	292	1	286	3.0e-58	218	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
643775808	562	47.79	4	559	10	571	0.0e+00	587	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
643775810	641	38.35	48	604	1	522	0.0e+00	542	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
643775811	689	29.75	236	555	32	336	1.0e-30	129	COG0642	Signal transduction histidine kinase	336
643775813	208	33.18	5	208	7	213	2.0e-37	148	COG3047	Outer membrane protein W	213
643775814	396	28.24	147	396	9	235	2.0e-24	107	COG0412	Dienelactone hydrolase	236
643775819	347	31.21	22	344	2	314	2.0e-35	143	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643775820	519	44.81	309	518	8	219	1.0e-54	208	COG0765	ABC-type amino acid transport system, permease component	222
643775821	253	44.81	4	244	1	236	1.0e-70	259	COG1126	ABC-type polar amino acid transport system, ATPase component	240
643775822	477	46.09	1	476	1	480	3.0e-129	455	COG0297	Glycogen synthase	487
643775823	418	53.32	9	415	2	386	0.0e+00	510	COG0448	ADP-glucose pyrophosphorylase	393
643775825	333	41.52	112	333	1	219	2.0e-45	176	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
643775828	304	26.35	1	295	8	319	2.0e-22	99.7	COG2367	Beta-lactamase class A	329
643775830	481	19.2	15	461	17	327	5.0e-17	82.7	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
643775831	523	26.9	98	512	31	384	2.0e-50	194	COG0006	Xaa-Pro aminopeptidase	384
643775832	911	20.87	289	887	64	619	8.0e-37	149	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
643775835	337	51.34	2	336	13	346	2.0e-113	402	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
643775836	254	39.06	6	249	3	249	6.0e-35	141	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643775837	1336	36.39	240	893	1	641	9.0e-103	369	COG1020	Non-ribosomal peptide synthetase component F	642
643775838	82	48.48	9	74	3	68	5.0e-13	66.1	COG3433	Aryl carrier domain	74
643775839	224	50	10	220	3	214	6.0e-66	243	COG1535	Isochorismate hydrolase	218
643775840	558	53.4	8	536	10	537	0.0e+00	653	COG1021	Non-ribosomal peptide synthetase component E (peptide arylation enzyme)	542
643775841	411	35.86	5	388	45	419	2.0e-80	293	COG1169	Isochorismate synthase EntC	423
643775842	385	19.67	1	357	1	319	9.0e-25	108	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
643775844	291	26.64	17	287	13	258	5.0e-25	108	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
643775845	276	40.15	12	267	3	258	2.0e-58	219	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
643775846	362	40.72	28	359	2	332	6.0e-50	191	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
643775847	230	25.28	17	174	5	172	1.0e-17	83.5	COG2091	Phosphopantetheinyl transferase	223
643775848	1313	29.56	910	1178	77	336	6.0e-35	143	COG0642	Signal transduction histidine kinase	336
643775849	218	36.45	1	197	3	193	5.0e-57	214	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
643775851	324	38.15	1	323	2	325	8.0e-68	250	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
643775852	320	31.34	44	317	4	285	2.0e-41	162	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
643775858	694	34.24	365	669	79	408	2.0e-32	134	COG0840	Methyl-accepting chemotaxis protein	408
643775859	285	25.64	160	275	11	127	3.0e-10	59.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643775862	225	26.11	1	203	5	201	2.0e-09	56.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643775863	456	37.88	6	456	1	392	7.0e-69	254	COG0183	Acetyl-CoA acetyltransferase	392
643775865	1078	38.89	198	982	17	790	0.0e+00	476	COG2374	Predicted extracellular nuclease	798
643775868	279	33.82	7	278	1	258	2.0e-38	153	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
643775870	427	18.23	54	403	51	382	1.0e-06	48.3	COG2814	Predicted arabinose efflux permease, MFS family	394
643775871	145	38.89	1	124	1	123	8.0e-29	119	COG3795	Uncharacterized conserved protein	123
643775872	435	50.12	11	423	4	411	2.0e-109	389	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
643775874	231	33.2	1	225	2	242	9.0e-33	133	COG3279	DNA-binding response regulator, LytR/AlgR family	244
643775875	429	25.78	35	429	2	419	3.0e-30	126	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
643775876	273	42.42	14	273	6	266	5.0e-65	241	COG0263	Glutamate 5-kinase	369
643775877	423	50.6	9	422	3	416	0.0e+00	471	COG0014	Gamma-glutamyl phosphate reductase	417
643775878	266	46.24	1	264	2	265	9.0e-67	247	COG0345	Pyrroline-5-carboxylate reductase	266
643775879	156	43.45	4	146	10	147	7.0e-26	109	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
643775880	372	32.22	79	344	2	258	2.0e-39	156	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
643775881	741	25.5	257	599	20	336	1.0e-34	141	COG0642	Signal transduction histidine kinase	336
643775882	181	26.32	1	161	3	192	1.0e-18	86.4	COG1335	Nicotinamidase-related amidase	205
643775885	426	23.56	40	406	34	393	6.0e-11	62.6	COG2223	Nitrate/nitrite transporter NarK	417
643775888	140	34.13	7	131	10	130	5.0e-15	73.4	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
643775889	146	28.36	11	144	6	137	2.0e-21	95.3	COG0824	Acyl-CoA thioesterase FadM	137
643775890	541	33.14	33	540	5	528	7.0e-107	381	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
643775891	392	42.97	12	389	5	392	3.0e-66	245	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643775892	281	34.35	18	278	2	257	2.0e-45	176	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
643775893	180	30.33	42	162	5	125	1.0e-10	59.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
643775894	252	32.1	2	232	1	243	2.0e-39	156	COG0300	Short-chain dehydrogenase	265
643775895	787	37.98	400	759	2	352	7.0e-96	345	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
643775896	413	54.36	7	403	8	407	9.0e-126	443	COG3844	Kynureninase	407
643775899	217	21.88	24	214	9	200	3.0e-06	45.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643775900	507	46.23	1	302	2	297	2.0e-102	366	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
643775903	429	20.31	109	417	5	318	1.0e-15	77.9	COG0642	Signal transduction histidine kinase	336
643775904	231	37.89	6	229	2	227	8.0e-45	173	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643775905	431	23.99	64	418	26	407	3.0e-28	119	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643775906	317	34.24	36	316	5	298	9.0e-43	167	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
643775909	1123	33.49	699	1096	1	415	3.0e-53	204	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
643775914	175	41.3	5	141	7	139	3.0e-08	51.9	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
643775915	335	32.41	218	325	18	125	8.0e-19	88	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643775916	367	32.98	264	356	31	124	2.0e-12	67.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643775918	229	43.16	1	224	5	238	8.0e-44	170	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
643775921	399	28.97	1	383	1	353	5.0e-52	198	COG1858	Cytochrome c peroxidase	364
643775923	175	21.43	1	167	4	145	2.0e-08	52.4	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
643775924	205	44.94	7	182	3	176	2.0e-48	185	COG0279	Phosphoheptose isomerase	176
643775926	666	29.02	68	661	15	557	1.0e-76	281	COG2936	Predicted acyl esterase	563
643775927	457	18.18	63	450	4	397	7.0e-15	75.3	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
643775929	156	20.65	7	151	2	156	1.0e-10	59.2	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
643775933	210	45.97	7	209	1	211	6.0e-47	180	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643775934	289	29.97	16	289	1	281	5.0e-27	115	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643775935	275	20.65	3	269	30	297	5.0e-11	62	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
643775936	262	21.93	4	262	7	252	9.0e-10	57.5	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
643775938	736	76.26	4	736	10	730	0.0e+00	1212	COG0376	Catalase (peroxidase I)	730
643775939	186	30.05	1	185	3	205	1.0e-17	82.7	COG0778	Nitroreductase	207
643775940	284	29.86	1	275	5	251	1.0e-36	146	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
643775943	161	37.91	8	159	7	159	6.0e-22	96.9	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
643775945	416	36.92	1	405	3	404	2.0e-86	313	COG2081	Predicted flavoprotein YhiN	408
643775946	271	45.87	12	240	6	245	5.0e-64	237	COG0020	Undecaprenyl pyrophosphate synthase	245
643775952	337	29.11	23	335	28	304	9.0e-32	131	COG3781	Predicted membrane chloride channel, bestrophin family	306
643775953	512	21.62	4	364	2	362	1.0e-24	108	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643775954	260	23.97	134	254	2	122	9.0e-12	64.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643775955	794	35.89	21	793	107	933	0.0e+00	729	COG0178	Excinuclease UvrABC ATPase subunit	935
643775956	146	33.56	6	144	1	149	1.0e-18	85.9	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
643775957	108	37.86	1	101	8	110	1.0e-11	61.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
643775965	372	31.05	2	362	1	371	3.0e-36	146	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643775966	301	41.51	28	292	1	264	4.0e-61	228	COG2362	D-aminopeptidase	274
643775967	635	30	23	280	1	277	4.0e-45	176	COG0515	Serine/threonine protein kinase	384
643775968	265	45.13	1	265	1	261	3.0e-77	281	COG0708	Exonuclease III	261
643775969	379	34.84	31	379	4	327	2.0e-57	216	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
643775971	161	35.67	3	157	2	158	5.0e-30	123	COG1528	Ferritin	167
643775975	252	27.36	8	217	19	223	2.0e-13	69.7	COG3361	Uncharacterized protein YqjF, DUF2071 family	240
643775976	167	19.08	8	154	10	159	6.0e-06	43.8	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
643775979	270	25.41	28	138	6	127	1.0e-08	54.2	COG4319	Ketosteroid isomerase homolog	137
643775980	164	28.97	7	145	4	146	4.0e-08	51	COG1247	L-amino acid N-acyltransferase YncA	169
643775985	244	19.77	58	220	22	188	2.0e-07	49.6	COG5661	Predicted secreted Zn-dependent protease	210
643775986	1046	25.36	618	1002	2	401	8.0e-37	149	COG1228	Imidazolonepropionase or related amidohydrolase	406
643775987	453	27.23	41	412	13	379	4.0e-32	132	COG1228	Imidazolonepropionase or related amidohydrolase	406
643776000	326	33	61	324	2	297	8.0e-36	144	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
643776001	510	42.15	18	496	2	467	2.0e-114	406	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643776003	298	33.88	177	297	1	121	1.0e-21	97.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643776008	161	47.71	5	155	4	151	4.0e-52	197	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
643776012	539	39	1	535	1	530	0.0e+00	494	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
643776016	659	30.38	116	438	27	362	1.0e-41	165	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643776018	856	29.9	86	386	2	294	9.0e-41	162	COG0515	Serine/threonine protein kinase	384
643776019	171	19.74	14	151	2	151	2.0e-06	45.8	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
643776020	222	28.93	12	199	1	190	6.0e-20	91.2	COG1407	Metallophosphoesterase superfamily enzyme	235
643776021	851	29.2	10	817	12	793	0.0e+00	515	COG1201	Lhr-like helicase	814
643776022	529	29.08	66	526	7	442	3.0e-61	229	COG1793	ATP-dependent DNA ligase	444
643776023	358	19.9	3	330	18	426	3.0e-30	126	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
643776025	207	44.55	5	207	1	211	5.0e-49	187	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643776029	369	23.2	33	281	1	228	4.0e-22	99.3	COG3386	Sugar lactone lactonase YvrE	307
643776034	310	21.48	9	303	2	282	1.0e-11	64.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643776035	380	25.16	87	377	66	383	3.0e-28	119	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643776039	108	37.5	1	102	2	105	6.0e-17	79.1	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
643776044	736	23.61	232	722	4	487	4.0e-30	126	COG0464	AAA+-type ATPase, SpoVK/Ycf46/Vps4 family	494
643776052	136	30	15	133	1	116	7.0e-14	70	COG3628	Phage baseplate assembly protein W	116
643776055	411	18.83	14	400	2	338	3.0e-19	90	COG3500	Phage protein D	350
643776061	1120	29.04	822	1111	97	380	1.0e-44	175	COG3497	Phage tail sheath protein FI	394
643776065	239	36.62	21	231	2	207	5.0e-35	141	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643776069	603	30.27	36	601	18	562	5.0e-70	259	COG2936	Predicted acyl esterase	563
643776071	283	33.87	160	283	1	124	9.0e-20	91.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643776072	341	20.54	43	341	66	386	4.0e-21	95.8	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643776083	240	32.81	106	232	2	126	8.0e-15	74.2	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
643776085	199	27.92	35	186	35	186	6.0e-17	80.8	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
643776087	181	30.07	14	166	5	149	1.0e-16	79.7	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
643776088	287	22.34	30	285	2	281	1.0e-17	83.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643776089	185	21.47	10	182	8	162	8.0e-11	60.3	COG0262	Dihydrofolate reductase	167
643776091	413	26.82	18	413	1	419	3.0e-30	126	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
643776092	423	25.82	25	423	1	419	9.0e-28	118	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
643776103	84	44.44	7	69	4	65	2.0e-15	74.1	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
643776106	687	22.61	64	657	68	620	4.0e-42	166	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
643776108	308	31.19	12	299	4	289	4.0e-47	182	COG1131	ABC-type multidrug transport system, ATPase component	293
643776109	129	33.61	1	122	1	122	3.0e-23	101	COG1725	DNA-binding transcriptional regulator YhcF, GntR family	125
643776113	97	46.24	1	93	5	97	2.0e-19	87.3	COG3636	DNA-binding prophage protein	100
643776117	234	27.96	120	212	26	118	3.0e-09	55.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643776118	704	22.19	40	672	4	620	1.0e-52	201	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
643776119	163	29.29	43	141	16	114	4.0e-10	57.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
643776121	332	24.73	41	297	1	279	5.0e-14	72	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643776124	257	35.83	7	237	1	239	6.0e-31	128	COG3279	DNA-binding response regulator, LytR/AlgR family	244
643776127	521	25.1	85	320	48	278	1.0e-13	71.6	COG4584	Transposase	278
643776128	254	35.25	1	241	5	247	9.0e-39	154	COG1484	DNA replication protein DnaC	254
643776132	137	31.62	5	120	1	117	6.0e-16	76.7	COG0789	DNA-binding transcriptional regulator, MerR family	124
643776136	149	44.97	1	149	8	156	9.0e-41	159	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
643776140	465	34.3	6	448	1	444	6.0e-39	155	COG1538	Outer membrane protein TolC	457
643776141	241	43.56	6	229	2	224	1.0e-62	232	COG1136	ABC-type lipoprotein export system, ATPase component	226
643776142	400	20.47	16	398	28	405	8.0e-11	61.8	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
643776143	383	27.42	1	369	3	362	4.0e-18	85.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643776144	202	21.78	1	202	1	200	1.0e-05	43.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643776145	389	42.15	62	384	1	310	4.0e-78	285	COG2826	Transposase and inactivated derivatives, IS30 family	318
643776149	320	31.17	15	307	18	286	3.0e-38	152	COG4974	Site-specific recombinase XerD	300
643776151	425	51.2	7	422	4	411	2.0e-114	405	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
643776152	270	41.34	7	260	3	252	2.0e-66	245	COG2107	Predicted periplasmic solute-binding protein	272
643776153	124	28.21	3	119	8	115	3.0e-14	70.8	COG3801	Uncharacterized protein	124
643776159	203	51.32	14	202	4	180	1.0e-37	149	COG3644	Uncharacterized protein	194
643776160	371	39.52	12	368	7	359	6.0e-87	314	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
643776161	194	22.16	1	194	6	199	3.0e-07	48.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643776163	894	15.82	56	891	16	763	5.0e-17	83.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643776164	445	45.12	12	445	9	445	0.0e+00	491	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
643776165	342	38.31	4	338	11	348	7.0e-56	211	COG3191	L-aminopeptidase/D-esterase	348
643776167	986	20.75	115	746	17	487	6.0e-18	86.9	COG4206	Outer membrane cobalamin receptor protein	608
643776168	427	32.71	7	423	1	408	2.0e-62	233	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643776169	477	25.85	5	458	6	476	2.0e-38	153	COG0591	Na+/proline symporter	493
643776170	261	35.43	7	250	1	251	7.0e-37	147	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643776171	358	49.29	8	357	3	345	3.0e-121	428	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
643776172	498	40.71	8	484	3	470	7.0e-121	427	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643776175	304	28.99	14	215	5	194	3.0e-19	89.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643776176	206	21.05	16	203	6	195	1.0e-06	47	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643776177	274	55.64	3	257	26	282	6.0e-58	217	COG5006	Threonine/homoserine efflux transporter RhtA	292
643776178	169	34.21	14	165	4	154	7.0e-25	106	COG1522	DNA-binding transcriptional regulator, Lrp family	154
643776182	206	30.77	51	206	40	190	3.0e-15	75.5	COG3544	Uncharacterized conserved protein, DUF305 family	190
643776188	407	30.06	64	407	5	322	3.0e-49	189	COG0270	Site-specific DNA-cytosine methylase	328
643776192	403	20.91	17	289	1	258	7.0e-06	45.5	COG2887	RecB family exonuclease	269
643776193	696	27.41	1	445	1	409	5.0e-42	166	COG1479	Uncharacterized conserved protein, contains ParB-like and HNH nuclease domains	409
643776196	556	45.12	4	537	1	530	0.0e+00	541	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
643776199	201	24.6	59	184	1	125	3.0e-09	55.3	COG0526	Thiol-disulfide isomerase or thioredoxin	127
643776200	352	35.74	14	342	1	331	8.0e-72	264	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
643776202	492	31.29	58	490	31	453	1.0e-63	237	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
643776203	401	32.25	49	374	2	331	2.0e-69	256	COG0836	Mannose-1-phosphate guanylyltransferase	333
643776204	271	40.87	17	268	8	257	9.0e-51	193	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
643776208	270	32.21	3	265	2	259	2.0e-41	163	COG0300	Short-chain dehydrogenase	265
643776209	363	45.93	1	208	1	208	2.0e-60	226	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
643776210	305	39.18	4	292	2	255	2.0e-62	232	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
643776213	402	24.56	1	393	1	380	4.0e-10	59.4	COG2814	Predicted arabinose efflux permease, MFS family	394
643776214	1106	19.5	87	409	52	332	2.0e-11	65.5	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
643776215	289	23.28	41	266	3	228	4.0e-18	85.5	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
643776216	88	43.4	2	54	4	56	5.0e-09	52.8	COG4877	Uncharacterized protein	63
643776220	232	28.51	1	231	1	241	2.0e-31	129	COG3279	DNA-binding response regulator, LytR/AlgR family	244
643776224	1064	28.07	2	1051	1	1008	0.0e+00	634	COG0841	Multidrug efflux pump subunit AcrB	1009
643776225	399	29.35	29	391	1	366	4.0e-24	105	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643776226	620	32.87	23	290	2	287	1.0e-45	178	COG0515	Serine/threonine protein kinase	384
643776227	300	37.33	1	299	2	276	9.0e-60	224	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
643776229	256	22.78	24	256	38	262	6.0e-07	48.1	COG3137	Putative salt-induced outer membrane protein YdiY	262
643776230	299	50.49	3	294	4	303	5.0e-71	261	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
643776231	221	47.29	16	215	20	221	1.0e-44	173	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
643776232	428	24.69	111	405	63	359	3.0e-18	86.9	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643776235	237	25.78	7	230	16	221	3.0e-11	62.3	COG2801	Transposase InsO and inactivated derivatives	232
643776236	191	33.12	5	161	4	136	3.0e-17	81.9	COG0262	Dihydrofolate reductase	167
643776240	180	38.2	3	180	3	177	7.0e-27	113	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643776242	955	49.84	3	950	8	935	0.0e+00	1173	COG0178	Excinuclease UvrABC ATPase subunit	935
643776244	416	22.05	14	400	2	384	8.0e-13	68.7	COG2814	Predicted arabinose efflux permease, MFS family	394
643776245	492	20.66	94	481	56	442	7.0e-18	85.6	COG1538	Outer membrane protein TolC	457
643776246	462	26.99	32	462	2	419	2.0e-29	123	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
643776247	464	21.51	1	421	4	369	8.0e-11	62.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643776250	633	24.58	335	626	16	309	3.0e-15	77.3	COG0657	Acetyl esterase/lipase	312
643776251	384	24.57	3	373	10	377	2.0e-22	100	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643776252	271	19.16	4	255	23	277	3.0e-06	46.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643776253	101	34.02	5	100	1	97	8.0e-16	75.3	COG2388	Predicted acetyltransferase, GNAT superfamily	99
643776255	262	40.08	9	261	12	265	2.0e-56	212	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
643776256	165	43.51	1	154	1	151	5.0e-47	180	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
643776266	393	55.56	21	267	3	254	9.0e-78	284	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
643776267	765	25	54	762	26	720	4.0e-72	266	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
643776268	155	52	1	148	4	153	7.0e-52	196	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
643776269	150	25.31	1	148	5	165	8.0e-10	56.5	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
643776271	138	31.9	1	110	1	116	5.0e-09	53.8	COG3070	Transcriptional regulator of competence genes, TfoX/Sxy family	121
643776272	197	43.72	1	196	5	203	2.0e-31	129	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
643776277	117	61.74	2	116	1	112	4.0e-39	153	COG2824	Uncharacterized Zn-ribbon-containing protein	112
643776278	785	21.57	51	474	11	437	3.0e-27	117	COG0612	Predicted Zn-dependent peptidase	438
643776284	303	36.81	7	290	5	291	4.0e-62	231	COG1131	ABC-type multidrug transport system, ATPase component	293
643776289	302	32.64	17	250	9	231	2.0e-31	129	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
643776290	407	28.5	8	386	5	375	4.0e-36	145	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643776291	116	27.97	1	116	1	117	5.0e-21	92.9	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
643776292	389	45.99	1	387	13	399	2.0e-73	269	COG3135	Predicted benzoate:H+ symporter BenE	402
643776293	145	52.14	1	140	4	143	7.0e-40	156	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
643776294	156	45.28	27	130	8	113	3.0e-15	74.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
643776296	203	38.94	3	203	4	207	1.0e-54	205	COG4832	Uncharacterized protein	207
643776302	250	24.14	1	242	1	259	4.0e-10	58.8	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
643776303	225	21.4	4	217	11	222	2.0e-09	56.5	COG4912	3-methyladenine DNA glycosylase AlkD	222
643776304	540	22.07	41	329	22	385	7.0e-18	85.8	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643776309	476	38.14	249	476	58	289	4.0e-54	205	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
643776315	707	25.93	19	679	3	666	3.0e-75	277	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
643776317	234	35.15	1	233	2	235	7.0e-51	194	COG1131	ABC-type multidrug transport system, ATPase component	293
643776324	297	18.24	92	245	2	159	7.0e-07	48.4	COG0681	Signal peptidase I	166
643776325	312	23.57	19	298	16	276	2.0e-06	46.8	COG5006	Threonine/homoserine efflux transporter RhtA	292
643776326	350	27.12	46	345	7	297	1.0e-28	120	COG1597	Diacylglycerol kinase family enzyme	301
643776327	254	36.96	5	252	3	251	2.0e-30	126	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643776328	493	57.36	227	491	2	263	4.0e-89	322	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
643776329	277	43.3	18	274	4	264	2.0e-63	236	COG2145	Hydroxyethylthiazole kinase, sugar kinase family	265
643776331	418	29.01	19	406	8	393	1.0e-57	217	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
643776332	103	36.84	3	91	9	103	2.0e-13	67.7	COG2944	DNA-binding transcriptional regulator YiaG, XRE-type HTH domain	104
643776337	191	28.69	64	180	26	147	7.0e-08	50.7	COG4803	Uncharacterized membrane protein	170
643776344	277	30.3	34	162	30	161	7.0e-09	54.7	COG3666	Transposase	161
643776347	553	21.8	1	388	1	367	1.0e-23	105	COG1479	Uncharacterized conserved protein, contains ParB-like and HNH nuclease domains	409
643776348	594	41.19	12	495	27	508	8.0e-113	401	COG0513	Superfamily II DNA and RNA helicase	513
643776350	118	30.17	3	118	1	105	5.0e-08	49.6	COG1734	RNA polymerase-binding transcription factor DksA	120
643776352	183	20	35	183	27	173	6.0e-10	57.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
643776353	515	19.85	1	362	7	385	4.0e-13	69.8	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
643776355	405	20.75	80	336	14	255	2.0e-10	60.5	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
643776356	181	34.76	1	162	1	163	2.0e-32	131	COG4681	Uncharacterized conserved protein YaeQ, suppresses RfaH defect	181
643776357	308	40.55	9	297	3	284	6.0e-65	241	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
643776358	262	33.85	3	256	1	249	1.0e-34	139	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643776360	211	23.61	1	211	1	211	2.0e-10	59.5	COG2910	Putative NADH-flavin reductase	211
643776361	561	57.19	10	561	1	554	0.0e+00	777	COG2759	Formyltetrahydrofolate synthetase	554
643776362	209	35.86	7	203	4	200	8.0e-44	170	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
643776363	498	40.12	1	484	27	513	5.0e-115	408	COG0513	Superfamily II DNA and RNA helicase	513
643776364	602	35.04	1	583	126	708	4.0e-129	455	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
643776366	548	33.1	17	281	2	277	2.0e-44	173	COG0515	Serine/threonine protein kinase	384
643776367	933	48	12	933	3	910	0.0e+00	984	COG2352	Phosphoenolpyruvate carboxylase	910
643776368	354	34.2	44	350	1	252	3.0e-39	156	COG0584	Glycerophosphoryl diester phosphodiesterase	257
643776370	224	29.1	39	219	15	201	1.0e-09	56.8	COG0666	Ankyrin repeat	235
643776372	1037	30.29	7	1011	2	1007	0.0e+00	694	COG0841	Multidrug efflux pump subunit AcrB	1009
643776374	459	26.74	10	452	17	442	4.0e-20	92.9	COG1538	Outer membrane protein TolC	457
643776375	217	24.52	12	164	4	158	6.0e-10	57.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643776376	118	62.73	8	117	8	116	4.0e-36	143	COG3169	Uncharacterized conserved protein, DUF486 family	116
643776377	428	38.53	1	304	1	326	9.0e-57	214	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
643776382	151	28.38	1	146	1	148	4.0e-22	97.3	COG1017	Hemoglobin-like flavoprotein	150
643776384	998	32.91	14	241	3	232	3.0e-21	97.7	COG3629	DNA-binding transcriptional activator of the SARP family	280
643776385	432	17.9	1	422	1	486	2.0e-41	163	COG3202	ATP/ADP translocase	509
643776386	339	25.58	1	230	1	249	1.0e-22	100	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643776387	338	23.53	1	244	1	261	6.0e-18	85.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643776388	408	35.98	30	382	2	311	3.0e-71	262	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
643776389	254	31.91	16	249	7	227	1.0e-40	160	COG4947	Esterase/lipase superfamily enzyme	227
643776390	293	33.56	16	293	2	289	3.0e-36	145	COG3176	Putative hemolysin	292
643776391	265	27.54	17	240	21	255	1.0e-21	96.9	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
643776392	160	33.33	14	137	6	130	1.0e-15	76.1	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
643776393	175	49.34	23	174	3	145	3.0e-40	158	COG3019	Uncharacterized conserved protein	149
643776394	752	59.83	10	488	1	481	0.0e+00	624	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
643776396	208	25.98	76	200	13	137	4.0e-07	48.4	COG2010	Cytochrome c, mono- and diheme variants	150
643776397	469	30.06	20	364	1	333	2.0e-40	160	COG0348	Polyferredoxin	386
643776399	262	35.84	11	234	8	224	1.0e-23	103	COG2836	Sulfite exporter TauE/SafE	232
643776400	844	37.12	103	813	1	704	0.0e+00	520	COG2217	Cation transport ATPase	713
643776401	58	31.03	1	58	1	57	4.0e-08	49.5	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
643776402	2777	39.08	1662	2771	3	1055	0.0e+00	838	COG3459	Cellobiose phosphorylase	1056
643776404	428	25.17	170	304	6	152	2.0e-08	54.2	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
643776405	554	32.43	20	552	14	523	1.0e-93	337	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
643776407	449	46.72	51	442	7	389	4.0e-105	375	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
643776408	370	26.82	55	345	27	309	3.0e-18	86.2	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
643776409	303	46.71	5	298	2	300	2.0e-94	339	COG0031	Cysteine synthase	300
643776411	239	32.77	1	233	1	226	2.0e-39	155	COG5587	Uncharacterized conserved protein, DUF2461 family	228
643776412	290	28.14	40	255	25	243	5.0e-28	118	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
643776413	328	44.38	5	327	2	321	9.0e-83	300	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
643776414	390	39.47	7	385	8	382	3.0e-95	342	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
643776415	203	33.94	35	143	17	125	2.0e-12	65.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
643776417	311	24.13	25	308	13	292	7.0e-07	48.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
643776419	392	34.02	62	392	22	353	2.0e-68	252	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
643776420	849	38.03	1	848	42	845	0.0e+00	658	COG1643	HrpA-like RNA helicase	845
643776425	670	58.18	12	670	7	663	0.0e+00	948	COG0021	Transketolase	663
643776428	495	29.7	1	493	8	567	1.0e-55	211	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
643776429	336	36.56	16	334	8	319	3.0e-65	242	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
643776430	397	26.82	1	389	4	385	2.0e-36	146	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643776432	474	22	22	473	4	407	1.0e-15	78.3	COG2223	Nitrate/nitrite transporter NarK	417
643776434	506	21.69	9	294	1	279	5.0e-15	76.2	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
643776435	127	46.88	1	127	2	129	9.0e-34	135	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
643776437	210	44.26	146	206	9	69	1.0e-11	63.1	COG3592	Uncharacterized Fe-S cluster protein YjdI	74
643776438	169	55	7	166	3	161	2.0e-62	231	COG0225	Peptide methionine sulfoxide reductase MsrA	174
643776439	170	61.76	18	152	1	136	5.0e-56	210	COG0229	Peptide methionine sulfoxide reductase MsrB	140
643776441	522	40.55	11	522	1	488	0.0e+00	530	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
643776443	781	25.1	43	771	22	723	6.0e-75	276	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
643776444	180	47.1	5	157	2	156	3.0e-51	194	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
643776451	438	32.14	14	271	2	279	1.0e-40	160	COG0515	Serine/threonine protein kinase	384
643776452	317	42.69	51	298	7	252	3.0e-56	212	COG0631	Serine/threonine protein phosphatase PrpC	262
643776453	627	32.76	8	275	1	287	2.0e-45	177	COG0515	Serine/threonine protein kinase	384
643776458	854	31.6	98	393	2	291	2.0e-41	164	COG0515	Serine/threonine protein kinase	384
643776459	191	26.09	11	191	1	178	7.0e-08	50.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643776461	226	44.25	1	220	1	225	4.0e-59	221	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643776463	106	35.63	17	102	9	95	1.0e-10	58.4	COG1605	Chorismate mutase	101
643776464	348	60.28	57	338	7	286	2.0e-103	369	COG2876	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	286
643776466	536	19.21	101	426	58	371	5.0e-07	49.9	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
643776467	483	32.78	23	440	7	412	3.0e-97	349	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
643776468	145	50.35	7	145	8	148	2.0e-33	134	COG1981	Uncharacterized membrane protein	149
643776471	496	52.46	22	488	5	420	0.0e+00	614	COG0499	S-adenosylhomocysteine hydrolase	420
643776472	310	27.43	146	289	57	231	3.0e-19	89.6	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
643776473	441	29.65	41	438	2	370	5.0e-24	106	COG3174	Uncharacterized membrane protein, DUF4010 family	371
643776474	275	38.91	11	267	5	261	2.0e-45	176	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
643776475	337	21.98	6	308	4	324	1.0e-12	67.4	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
643776476	306	27.59	171	304	7	151	6.0e-09	55	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
643776477	461	34.54	49	455	62	432	6.0e-55	208	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
643776478	473	26.95	1	473	3	478	3.0e-59	222	COG4784	Putative Zn-dependent protease	479
643776483	619	26.48	44	417	2	383	2.0e-45	177	COG0515	Serine/threonine protein kinase	384
643776484	1175	22.83	10	1125	19	1140	6.0e-70	259	COG3523	Type VI protein secretion system component VasK	1188
643776485	242	30.49	12	230	41	258	4.0e-25	108	COG3455	Type VI protein secretion system component VasF	262
643776486	459	32.89	5	452	1	441	5.0e-72	265	COG3522	Predicted component of the type VI protein secretion system	446
643776488	448	31.57	1	448	1	446	6.0e-71	261	COG3522	Predicted component of the type VI protein secretion system	446
643776489	168	49.7	2	168	1	165	6.0e-44	170	COG3516	Predicted component of the type VI protein secretion system	169
643776490	492	55.67	1	491	1	494	0.0e+00	691	COG3517	Predicted component of the type VI protein secretion system	495
643776491	163	28.66	1	160	1	158	4.0e-26	110	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
643776492	233	34.09	2	229	6	263	9.0e-34	137	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion	273
643776493	626	25.79	11	319	7	310	6.0e-15	76.3	COG3515	Predicted component of the type VI protein secretion system	346
643776494	163	37.18	5	160	2	154	1.0e-19	89.6	COG3518	Predicted component of the type VI protein secretion system	157
643776495	617	39.94	1	617	1	621	0.0e+00	479	COG3519	Type VI protein secretion system component VasA	621
643776496	378	42.24	56	376	22	331	3.0e-65	242	COG3520	Predicted component of the type VI protein secretion system	335
643776497	887	39.32	11	865	1	766	0.0e+00	762	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
643776498	734	33.92	1	558	4	539	7.0e-105	375	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
643776500	99	42.16	1	99	1	98	9.0e-08	48.4	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
643776501	127	43.2	6	121	4	126	3.0e-31	127	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
643776506	731	33.99	6	711	1	695	0.0e+00	518	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
643776507	1163	28.4	236	1155	108	962	3.0e-129	457	COG4403	Lantibiotic modifying enzyme	963
643776512	279	22.5	151	269	7	122	5.0e-11	61.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643776513	131	46.22	2	120	23	127	5.0e-28	116	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
643776514	306	29.53	13	194	15	205	1.0e-24	107	COG0705	Membrane associated serine protease, rhomboid family	228
643776515	344	37.75	3	341	1	317	3.0e-73	269	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
643776518	186	37.85	11	184	4	180	4.0e-23	101	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643776523	406	41.54	10	406	6	401	0.0e+00	475	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
643776524	309	33.33	3	309	14	303	8.0e-51	194	COG0010	Arginase family enzyme	305
643776525	140	31.69	1	139	6	147	1.0e-18	85.9	COG1522	DNA-binding transcriptional regulator, Lrp family	154
643776527	479	56.91	24	333	2	300	4.0e-105	375	COG0031	Cysteine synthase	300
643776529	283	48.21	34	282	10	260	7.0e-79	287	COG3823	Glutamine cyclotransferase	262
643776530	187	28.48	21	185	2	166	2.0e-25	108	COG3663	G:T/U-mismatch repair DNA glycosylase	169
643776531	912	44.84	3	903	4	843	0.0e+00	867	COG0249	DNA mismatch repair ATPase MutS	843
643776533	385	22.07	18	376	6	331	2.0e-25	110	COG1466	DNA polymerase III, delta subunit	334
643776535	196	39.89	9	196	1	180	1.0e-30	126	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643776536	186	25.16	41	184	5	158	3.0e-08	51.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
643776538	472	28.97	30	450	13	438	3.0e-63	236	COG0612	Predicted Zn-dependent peptidase	438
643776539	435	28.34	1	427	13	438	3.0e-59	223	COG0612	Predicted Zn-dependent peptidase	438
643776542	465	34.83	1	465	1	427	4.0e-84	305	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
643776545	474	41.77	2	461	8	451	1.0e-108	386	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643776546	212	36.18	12	206	6	203	2.0e-42	165	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
643776548	215	63.77	10	215	4	210	2.0e-80	292	COG0035	Uracil phosphoribosyltransferase	210
643776549	217	20.59	8	195	19	215	3.0e-10	58.9	COG1655	Uncharacterized protein, DUF2225 family	267
643776551	452	40.66	7	452	5	454	2.0e-109	389	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
643776552	570	33.55	265	560	4	296	3.0e-50	193	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
643776553	80	60.61	15	80	9	74	1.0e-24	104	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
