gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
638996219	422	39.08	11	419	1	403	9.0e-93	334	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
638996220	325	56.31	3	325	1	324	0.0e+00	465	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
638996221	389	38.48	20	370	2	357	7.0e-101	361	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
638996223	659	46.31	1	649	2	643	0.0e+00	683	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
638996225	263	36.68	1	253	6	256	5.0e-45	174	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638996226	534	44.4	12	534	1	526	0.0e+00	622	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
638996227	381	45.9	1	381	2	391	2.0e-95	342	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638996228	385	46.51	5	382	1	387	2.0e-97	349	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638996229	258	22.73	1	258	19	289	7.0e-32	130	COG1234	Ribonuclease BN, tRNA processing enzyme	292
638996231	155	15.91	2	133	35	144	2.0e-08	51.8	COG1225	Peroxiredoxin	157
638996236	307	25.23	1	302	4	329	4.0e-27	115	COG0673	Predicted dehydrogenase	342
638996238	535	29.19	166	535	43	408	1.0e-38	155	COG0840	Methyl-accepting chemotaxis protein	408
638996239	159	30.77	4	153	8	162	4.0e-22	97.4	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
638996241	148	34.23	33	143	29	138	2.0e-14	71.6	COG4446	Uncharacterized conserved protein, DUF1499 family	141
638996249	464	19.62	41	458	17	365	7.0e-15	75.9	COG1106	ATPase/GTPase, AAA15 family	371
638996250	317	33.45	22	310	18	298	8.0e-50	191	COG4974	Site-specific recombinase XerD	300
638996252	247	27.69	1	239	7	247	2.0e-32	133	COG1484	DNA replication protein DnaC	254
638996253	544	28.06	102	292	52	246	5.0e-19	89.7	COG4584	Transposase	278
638996257	1098	20.25	245	949	4	661	4.0e-18	87.6	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
638996262	496	43.16	22	491	1	453	0.0e+00	490	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
638996263	1542	57.23	714	1207	1	485	0.0e+00	661	COG0069	Glutamate synthase domain 2	485
638996265	374	27.35	23	365	7	354	7.0e-38	151	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
638996266	214	43.56	11	206	5	204	7.0e-44	170	COG3132	Uncharacterized conserved protein YceH, UPF0502 family	215
638996268	508	20.57	158	507	61	407	1.0e-32	135	COG0840	Methyl-accepting chemotaxis protein	408
638996270	245	47.33	3	244	6	245	3.0e-78	284	COG1540	Lactam utilization protein B (function unknown)	252
638996271	232	36.36	8	227	4	221	4.0e-55	208	COG2049	Allophanate hydrolase subunit 1	223
638996272	304	36.18	5	301	3	306	3.0e-69	255	COG1984	Allophanate hydrolase subunit 2	314
638996273	445	26.46	19	443	39	457	1.0e-39	157	COG1538	Outer membrane protein TolC	457
638996275	144	36.43	6	133	18	141	2.0e-19	88.9	COG3151	Uncharacterized protein YqiB, DUF1249 family	147
638996277	263	27.7	5	263	1	270	3.0e-28	118	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
638996278	631	48.59	1	629	1	632	0.0e+00	835	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
638996281	149	36.89	6	122	1	122	1.0e-18	85.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
638996283	185	32.68	1	153	1	148	1.0e-22	99.7	COG0431	NAD(P)H-dependent FMN reductase	184
638996284	185	29.95	15	183	16	196	5.0e-20	91	COG0655	Multimeric flavodoxin WrbA	207
638996287	290	20.88	3	287	1	267	6.0e-15	75	COG3393	Predicted acetyltransferase, GNAT family	268
638996288	521	29.94	26	346	33	343	2.0e-50	194	COG3866	Pectate lyase	345
638996290	524	47.92	20	521	1	498	0.0e+00	468	COG1292	Choline-glycine betaine transporter	537
638996292	651	35.78	25	648	1	610	0.0e+00	545	COG2905	Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains	610
638996295	1291	23.17	38	511	2	436	6.0e-39	157	COG0366	Glycosidase	505
638996296	1012	23.62	135	637	2	486	4.0e-41	163	COG0366	Glycosidase	505
638996301	1080	32.34	1	1041	1	1045	0.0e+00	578	COG1330	Exonuclease V gamma subunit	1078
638996302	1130	28.26	4	1094	2	1139	0.0e+00	546	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
638996303	583	29.5	88	583	143	692	6.0e-70	258	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
638996304	295	28.62	1	283	3	283	8.0e-38	150	COG1597	Diacylglycerol kinase family enzyme	301
638996305	132	31.82	1	130	2	131	8.0e-21	92.6	COG0824	Acyl-CoA thioesterase FadM	137
638996306	324	46.11	158	322	16	179	3.0e-39	156	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638996307	415	35.07	5	404	7	377	2.0e-69	256	COG3268	Uncharacterized conserved protein, related to short-chain dehydrogenases	382
638996310	480	36.84	406	479	7	82	1.0e-13	71.9	COG1264	Phosphotransferase system IIB components	88
638996310	480	37.26	5	392	3	393	7.0e-62	232	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
638996311	840	41.46	171	252	7	88	3.0e-18	87.9	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
638996311	840	48.97	2	146	7	151	1.0e-44	175	COG2190	Phosphotransferase system IIA component	156
638996311	840	50.62	280	836	3	570	0.0e+00	644	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
638996314	608	55.41	1	608	1	597	0.0e+00	809	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
638996315	452	53.49	1	452	1	458	0.0e+00	587	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
638996319	671	19.5	403	671	51	328	2.0e-18	88.3	COG0642	Signal transduction histidine kinase	336
638996320	463	43.13	4	456	3	463	6.0e-125	441	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638996321	852	24.1	371	562	46	240	7.0e-08	53	COG3063	Tfp pilus assembly protein PilF	250
638996322	374	25.07	36	374	55	372	7.0e-20	91.8	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
638996323	379	23.94	4	333	14	364	6.0e-21	95.4	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
638996324	364	23.75	9	360	2	377	2.0e-23	103	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638996325	393	23.82	38	375	53	381	1.0e-27	118	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638996328	599	27.36	68	597	41	566	3.0e-66	246	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
638996329	472	20.07	123	397	100	380	9.0e-08	51.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638996331	657	28.23	1	622	1	521	6.0e-84	305	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
638996332	408	20.1	37	405	5	381	5.0e-15	75.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638996333	433	16.38	31	423	18	409	3.0e-09	57.1	COG3307	O-antigen ligase	424
638996334	189	30.56	48	188	2	139	1.0e-21	96.5	COG0394	Protein-tyrosine-phosphatase	139
638996335	379	24.93	8	363	5	373	3.0e-31	129	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638996336	393	24.7	24	337	16	333	4.0e-22	99.7	COG3919	Predicted ATP-dependent carboligase, ATP-grasp superfamily	415
638996345	392	23.56	1	366	1	365	9.0e-25	108	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638996347	804	17.18	43	671	52	696	2.0e-37	151	COG3250	Beta-galactosidase/beta-glucuronidase	808
638996349	377	24.32	18	360	12	362	8.0e-13	68.3	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
638996357	503	20.47	10	438	14	458	1.0e-19	91.3	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
638996359	456	40.79	231	456	3	226	2.0e-60	226	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
638996362	430	39.77	8	428	11	436	1.0e-124	440	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
638996363	334	31.35	1	248	9	258	3.0e-29	122	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
638996364	283	25.68	43	263	26	218	2.0e-09	56.4	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
638996365	316	31.73	4	313	1	310	3.0e-33	136	COG0679	Predicted permease	311
638996368	930	40.38	612	766	11	161	2.0e-16	82	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
638996368	930	42.75	3	523	1	514	1.0e-121	431	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
638996369	120	44.95	1	105	1	109	3.0e-24	103	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
638996370	507	31.29	1	496	1	498	5.0e-52	199	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
638996371	165	38.46	9	164	3	158	5.0e-32	130	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
638996372	89	44.32	1	88	2	89	6.0e-08	49.3	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
638996373	116	38.6	1	114	1	113	2.0e-19	87.6	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
638996374	171	33.13	13	169	8	165	1.0e-18	86.2	COG3663	G:T/U-mismatch repair DNA glycosylase	169
638996375	720	45.98	7	651	1	652	0.0e+00	569	COG0210	Superfamily I DNA or RNA helicase	655
638996379	296	18.66	1	274	4	284	4.0e-28	118	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
638996380	163	55.35	1	159	19	170	9.0e-48	182	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
638996381	508	38.24	14	494	4	491	2.0e-104	373	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
638996382	695	51.45	9	693	2	686	0.0e+00	865	COG0855	Polyphosphate kinase	696
638996384	418	51.57	198	418	66	282	3.0e-61	229	COG3833	ABC-type maltose transport system, permease component	282
638996385	524	32.84	251	517	39	288	4.0e-42	166	COG1175	ABC-type sugar transport system, permease component	295
638996386	393	31.3	7	393	21	412	1.0e-77	283	COG2182	Maltose-binding periplasmic protein MalE	420
638996388	608	31.66	229	607	34	408	3.0e-41	163	COG0840	Methyl-accepting chemotaxis protein	408
638996390	409	39.16	8	336	1	324	4.0e-86	312	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
638996391	329	64.74	1	329	1	323	0.0e+00	509	COG0435	Glutathionyl-hydroquinone reductase	324
638996393	137	46.09	10	137	6	126	5.0e-22	96.7	COG3245	Cytochrome c5	126
638996394	289	34.97	4	286	3	274	7.0e-54	204	COG0388	Predicted amidohydrolase	274
638996395	749	25.12	18	633	2	618	5.0e-59	223	COG0210	Superfamily I DNA or RNA helicase	655
638996397	472	35.39	35	455	20	424	4.0e-73	269	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
638996398	214	33.8	2	196	74	286	8.0e-39	153	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
638996402	306	22.36	59	303	63	290	2.0e-06	46.8	COG5006	Threonine/homoserine efflux transporter RhtA	292
638996403	336	64.35	5	335	2	325	0.0e+00	480	COG0158	Fructose-1,6-bisphosphatase	326
638996406	139	48.09	2	131	3	133	2.0e-29	121	COG0355	FoF1-type ATP synthase, epsilon subunit	135
638996407	466	71.95	1	460	1	460	0.0e+00	789	COG0055	FoF1-type ATP synthase, beta subunit	468
638996408	288	52.45	5	287	1	286	9.0e-96	343	COG0224	FoF1-type ATP synthase, gamma subunit	287
638996409	514	63.99	4	514	3	502	0.0e+00	807	COG0056	FoF1-type ATP synthase, alpha subunit	504
638996410	178	43.82	1	177	1	178	2.0e-36	145	COG0712	FoF1-type ATP synthase, delta subunit	178
638996413	297	40.17	60	297	24	246	9.0e-49	187	COG0356	FoF1-type ATP synthase, membrane subunit a	246
638996415	296	38.28	38	291	2	240	2.0e-34	139	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
638996416	271	41.7	1	257	1	258	1.0e-61	230	COG1192	Cellulose biosynthesis protein BcsQ	259
638996417	216	42.86	5	206	1	210	3.0e-49	188	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
638996418	628	64.1	3	625	1	621	0.0e+00	965	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
638996420	797	33.45	207	763	72	625	2.0e-120	426	COG1067	Predicted ATP-dependent protease	647
638996422	283	39.93	1	283	3	268	4.0e-89	321	COG0207	Thymidylate synthase	268
638996423	282	42.11	1	269	6	286	2.0e-61	228	COG0682	Prolipoprotein diacylglyceryltransferase	287
638996424	401	25.37	3	401	13	373	2.0e-16	80.6	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
638996426	94	53.16	9	87	5	81	6.0e-23	98.8	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
638996427	262	29.59	2	259	1	267	4.0e-35	141	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
638996428	217	21.9	2	207	1	198	2.0e-10	59.2	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
638996430	487	53.88	2	483	1	490	0.0e+00	548	COG0606	Predicted ATPase with chaperone activity	490
638996431	253	36.5	1	250	1	260	1.0e-56	213	COG0708	Exonuclease III	261
638996433	228	33.64	15	225	1	201	7.0e-44	170	COG0461	Orotate phosphoribosyltransferase	201
638996436	233	25.89	1	222	1	220	3.0e-21	95.4	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
638996437	416	45.45	1	391	1	394	5.0e-124	438	COG0019	Diaminopimelate decarboxylase	394
638996438	274	53.31	3	273	1	270	2.0e-94	338	COG0253	Diaminopimelate epimerase	272
638996439	223	30.37	9	220	3	213	1.0e-30	126	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
638996440	296	20.27	7	292	46	322	3.0e-26	112	COG2988	Succinylglutamate desuccinylase	324
638996441	187	35.03	10	186	3	176	7.0e-43	166	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
638996442	169	43.11	2	161	1	163	3.0e-40	157	COG0262	Dihydrofolate reductase	167
638996443	285	39.26	7	271	12	276	8.0e-55	207	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
638996445	409	20.11	36	403	32	390	1.0e-13	71.8	COG2814	Predicted arabinose efflux permease, MFS family	394
638996446	362	28.72	4	351	30	403	1.0e-68	253	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
638996448	556	33.27	17	531	1	472	5.0e-100	358	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
638996450	415	17.69	15	402	15	394	3.0e-12	66.8	COG2814	Predicted arabinose efflux permease, MFS family	394
638996451	405	25.77	10	335	4	278	9.0e-32	131	COG0462	Phosphoribosylpyrophosphate synthetase	314
638996452	194	44.32	23	194	10	184	4.0e-44	170	COG3575	Uncharacterized protein	184
638996454	647	30.92	247	647	13	408	4.0e-46	179	COG0840	Methyl-accepting chemotaxis protein	408
638996456	507	25.57	209	506	30	334	3.0e-26	113	COG0642	Signal transduction histidine kinase	336
638996459	227	45.18	8	226	2	228	3.0e-49	188	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638996460	433	19.33	50	383	54	403	4.0e-06	46.4	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
638996462	254	35.19	16	248	24	256	7.0e-57	214	COG0159	Tryptophan synthase alpha chain	265
638996463	420	57.03	5	395	5	392	0.0e+00	557	COG0133	Tryptophan synthase beta chain	396
638996464	151	23.75	1	151	8	167	4.0e-08	51.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638996466	117	27.93	4	113	2	112	8.0e-16	75.8	COG3791	Uncharacterized conserved protein	133
638996470	346	38.51	9	330	9	328	3.0e-72	265	COG3938	Proline racemase	341
638996471	379	31.89	1	362	1	326	2.0e-48	187	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
638996472	339	30.97	2	337	1	332	2.0e-52	199	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
638996473	191	24.39	20	183	8	169	6.0e-18	84.2	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
638996474	422	41.18	43	416	1	374	2.0e-77	283	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
638996475	147	35.57	1	147	4	150	7.0e-17	80	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
638996477	206	27.27	1	186	3	199	3.0e-14	71.9	COG1011	FMN phosphatase YigB, HAD superfamily	229
638996479	144	34.51	1	113	1	113	4.0e-24	104	COG0789	DNA-binding transcriptional regulator, MerR family	124
638996480	153	23.03	2	153	32	182	3.0e-14	71.2	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
638996481	456	32.5	203	456	1	274	6.0e-38	152	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
638996481	456	47.25	3	184	5	179	7.0e-50	191	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
638996482	156	45.83	1	156	1	168	1.0e-45	176	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
638996487	272	25.58	1	262	6	305	2.0e-34	139	COG0078	Ornithine carbamoyltransferase	310
638996491	440	19.63	1	433	7	430	3.0e-33	136	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
638996492	670	26.85	262	667	6	408	3.0e-44	173	COG0840	Methyl-accepting chemotaxis protein	408
638996495	141	35.71	1	132	5	144	7.0e-10	56.7	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
638996496	154	33.57	1	142	1	140	2.0e-13	68.7	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
638996497	182	31.71	37	159	6	125	1.0e-11	63.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
638996498	605	68.76	1	605	1	603	0.0e+00	992	COG1217	Predicted membrane GTPase involved in stress response	603
638996505	195	37.08	4	181	9	184	4.0e-37	147	COG2840	DNA-nicking endonuclease, Smr domain	184
638996506	233	41.13	4	231	1	228	5.0e-56	210	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638996507	475	29.7	165	465	37	334	8.0e-45	174	COG0642	Signal transduction histidine kinase	336
638996508	296	22.78	26	286	4	279	3.0e-13	69.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638996509	175	45.22	19	175	1	154	3.0e-37	148	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
638996511	237	55.22	4	225	1	226	6.0e-72	263	COG0120	Ribose 5-phosphate isomerase	227
638996512	504	53.76	1	342	4	347	2.0e-117	416	COG1171	Threonine dehydratase	347
638996513	466	32.49	72	463	5	378	8.0e-60	224	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
638996514	208	28.03	6	160	3	152	2.0e-15	76.1	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
638996515	338	20.65	3	330	1	327	3.0e-22	99.6	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
638996516	454	44.49	2	453	1	462	0.0e+00	474	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638996518	546	30.37	201	546	63	408	4.0e-36	146	COG0840	Methyl-accepting chemotaxis protein	408
638996520	130	18.71	5	120	1	138	1.0e-05	42.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
638996525	327	27.1	22	324	15	332	4.0e-46	178	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
638996526	178	28.74	3	166	1	174	2.0e-22	98.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638996530	156	50	1	156	1	156	8.0e-46	176	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
638996531	335	42.25	1	329	7	335	6.0e-84	304	COG4448	L-asparaginase II	339
638996533	156	24.62	27	155	13	141	2.0e-08	52.3	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
638996534	389	55.64	1	389	1	390	0.0e+00	484	COG3825	Uncharacterized conserved protein,  contains von Willebrand factor type A (vWA) domain	393
638996535	281	26.59	9	265	26	278	2.0e-33	136	COG0714	MoxR-like ATPase	329
638996536	263	22.97	1	263	5	284	9.0e-28	117	COG1946	Acyl-CoA thioesterase	289
638996537	402	21.57	98	402	54	334	1.0e-20	94.5	COG0642	Signal transduction histidine kinase	336
638996539	301	21.05	16	300	8	241	2.0e-06	46.7	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
638996540	644	20.13	37	636	38	604	4.0e-22	100	COG4206	Outer membrane cobalamin receptor protein	608
638996542	337	20.48	165	330	2	167	2.0e-11	63.2	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638996543	320	26.9	10	163	2	167	1.0e-12	67.7	COG2203	GAF domain	175
638996543	320	34.68	145	317	1	173	7.0e-32	131	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638996544	192	32.29	3	189	1	180	2.0e-16	79.1	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
638996545	620	33.71	8	616	1	609	8.0e-124	438	COG2905	Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains	610
638996546	566	40.11	2	560	5	529	0.0e+00	495	COG4147	Na+(or H+)/acetate symporter ActP	529
638996547	88	46.07	1	88	1	88	7.0e-23	98.9	COG4327	Uncharacterized membrane protein	101
638996548	650	24.53	1	313	5	320	6.0e-29	123	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
638996548	650	44.97	483	648	13	181	2.0e-40	161	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638996550	499	42.43	1	499	5	496	0.0e+00	539	COG2317	Zn-dependent carboxypeptidase, M32 family	497
638996551	484	25.49	178	478	20	318	5.0e-51	195	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
638996552	375	31.14	1	153	7	173	6.0e-16	78.9	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
638996554	469	16.85	82	425	79	436	3.0e-07	50.2	COG2211	Na+/melibiose symporter or related transporter	467
638996555	482	24.64	11	216	16	223	6.0e-26	112	COG1131	ABC-type multidrug transport system, ATPase component	293
638996555	482	42.26	233	469	11	248	1.0e-58	221	COG1119	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA	257
638996557	444	33.57	1	423	2	375	2.0e-72	266	COG0006	Xaa-Pro aminopeptidase	384
638996558	212	29.48	28	200	8	176	5.0e-21	94.6	COG3079	Uncharacterized conserved protein YgfB, UPF0149 family	186
638996560	106	40.86	4	96	1	93	2.0e-13	67.6	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
638996561	196	35.08	5	194	3	191	8.0e-40	156	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
638996563	160	51.61	1	154	2	154	9.0e-49	185	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
638996565	147	44.2	11	147	12	148	4.0e-30	123	COG2847	Copper(I)-binding protein	151
638996568	151	51.02	1	147	2	146	1.0e-44	172	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
638996572	150	32.11	42	150	2	106	8.0e-15	73	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
638996573	106	47.17	3	106	1	106	4.0e-27	112	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
638996575	347	25.89	1	198	13	235	2.0e-22	100	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
638996575	347	37.5	251	344	6	100	5.0e-14	72.3	COG0607	Rhodanese-related sulfurtransferase	110
638996576	582	19.96	97	569	1	472	1.0e-39	158	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638996582	270	39.07	1	270	6	283	3.0e-73	268	COG0169	Shikimate 5-dehydrogenase	283
638996583	551	29.4	24	530	145	638	8.0e-70	258	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
638996584	243	45.49	1	232	8	240	3.0e-52	198	COG0805	Sec-independent protein secretion pathway component TatC	255
638996585	125	34.88	1	86	1	86	1.0e-11	62.3	COG1826	Sec-independent protein translocase protein TatA	94
638996586	78	29.73	3	76	1	74	3.0e-10	56.5	COG1826	Sec-independent protein translocase protein TatA	94
638996587	119	41.51	2	104	1	103	2.0e-25	107	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
638996588	110	47.92	5	100	1	91	5.0e-20	89.5	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
638996589	541	46.98	2	510	6	508	0.0e+00	479	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
638996590	205	24.49	7	202	10	204	6.0e-19	87.6	COG3165	Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain	204
638996591	255	59.83	17	254	1	237	4.0e-86	311	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
638996592	332	54.29	10	331	5	330	7.0e-129	453	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
638996594	418	74.58	1	417	4	419	0.0e+00	702	COG1158	Transcription termination factor Rho	422
638996596	658	34.34	294	657	53	408	3.0e-46	180	COG0840	Methyl-accepting chemotaxis protein	408
638996597	507	27.24	221	506	1	274	4.0e-34	139	COG0388	Predicted amidohydrolase	274
638996598	621	46.62	18	621	20	616	0.0e+00	586	COG3211	Secreted phosphatase, PhoX family	616
638996600	231	27.23	1	217	6	230	4.0e-23	101	COG0300	Short-chain dehydrogenase	265
638996601	373	31.2	3	363	11	385	3.0e-57	215	COG0499	S-adenosylhomocysteine hydrolase	420
638996604	526	41.98	1	519	11	527	0.0e+00	545	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
638996607	547	37.95	33	416	30	448	1.0e-82	300	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
638996608	1190	37.21	7	390	3	362	3.0e-94	340	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
638996614	491	26.52	1	308	20	307	2.0e-21	97.8	COG3397	Predicted carbohydrate-binding protein, contains CBM5 and CBM33 domains	308
638996617	147	26.19	1	121	10	135	1.0e-09	55.7	COG0645	Predicted kinase	170
638996618	462	35.61	1	462	27	493	1.0e-107	383	COG0513	Superfamily II DNA and RNA helicase	513
638996619	254	24.22	5	250	3	258	5.0e-09	55	COG0730	Uncharacterized membrane protein YfcA	258
638996620	300	42.22	125	298	2	180	8.0e-41	161	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638996621	515	25.91	7	512	3	517	9.0e-65	241	COG4943	Environmental sensor c-di-GMP phosphodiesterase, contains periplasmic CSS-motif sensor and cytoplasmic EAL domain	524
638996623	255	42.06	10	255	6	250	5.0e-43	168	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638996624	297	33.96	1	106	15	120	5.0e-22	98.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638996626	302	30.13	1	290	1	311	2.0e-37	149	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
638996628	210	19.54	2	173	12	184	1.0e-10	60	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638996630	247	46.03	5	243	10	241	4.0e-65	241	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
638996632	732	29.87	72	514	72	507	6.0e-96	345	COG3227	Zn-dependent metalloprotease	507
638996635	234	21.62	5	232	24	282	1.0e-11	64	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638996636	536	31.21	5	519	4	502	4.0e-76	279	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
638996638	610	37.26	15	599	1	566	2.0e-130	459	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
638996639	620	35.34	18	597	12	567	3.0e-123	436	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
638996640	224	22.89	9	173	3	168	3.0e-08	52	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638996641	380	34.23	102	357	5	250	2.0e-43	169	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
638996642	302	30.61	11	246	4	231	2.0e-29	123	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638996644	191	20.23	1	164	1	169	1.0e-06	46.9	COG3637	Opacity protein and related surface antigens	199
638996645	396	30.47	267	394	7	127	7.0e-18	85.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638996648	538	31.69	14	196	1	182	5.0e-25	109	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638996649	223	40.65	17	223	77	289	5.0e-51	194	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
638996650	309	33.03	1	307	3	321	1.0e-65	243	COG3491	Isopenicillin N synthase and related dioxygenases	322
638996651	328	49.54	1	327	1	304	4.0e-76	278	COG1079	ABC-type uncharacterized transport system, permease component	304
638996652	373	41.36	5	357	7	350	1.0e-69	257	COG4603	ABC-type uncharacterized transport system, permease component	356
638996653	525	49.6	9	509	1	500	0.0e+00	619	COG3845	ABC-type uncharacterized transport system, ATPase component	501
638996654	312	45.11	1	310	32	343	3.0e-71	262	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
638996656	550	23.53	1	530	6	547	7.0e-56	212	COG0747	ABC-type transport system, periplasmic component	556
638996657	313	36.07	10	131	1	121	2.0e-20	93	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638996657	313	38.96	157	310	1	154	4.0e-39	155	COG3449	DNA gyrase inhibitor GyrI	154
638996659	156	33.63	15	126	12	122	9.0e-12	63.1	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
638996661	135	27.07	1	123	3	130	3.0e-08	51	COG3153	Predicted N-acetyltransferase YhbS	171
638996663	671	31.47	66	485	1	391	2.0e-63	237	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
638996666	705	40.33	525	700	2	181	3.0e-39	157	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638996671	303	26.78	14	302	1	294	3.0e-26	112	COG0583	DNA-binding transcriptional regulator, LysR family	297
638996672	286	26.45	43	283	82	298	8.0e-26	111	COG2382	Enterochelin esterase or related enzyme	299
638996675	294	23.81	2	286	1	293	1.0e-25	110	COG0583	DNA-binding transcriptional regulator, LysR family	297
638996677	430	28.35	1	382	1	378	2.0e-46	179	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638996679	250	46.77	3	245	7	254	1.0e-52	200	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
638996682	718	25.48	10	718	16	719	8.0e-62	232	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
638996684	234	38.6	3	222	2	228	7.0e-39	154	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638996685	233	29.15	19	215	13	208	3.0e-23	101	COG0811	Biopolymer transport protein ExbB/TolQ	216
638996687	134	27.64	11	130	14	131	2.0e-10	58.3	COG0848	Biopolymer transport protein ExbD	137
638996688	136	24.14	21	133	18	133	3.0e-07	47.9	COG0848	Biopolymer transport protein ExbD	137
638996689	290	21.61	86	276	36	232	3.0e-11	62.9	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
638996691	654	29.2	244	654	3	408	1.0e-55	211	COG0840	Methyl-accepting chemotaxis protein	408
638996692	328	30.72	2	325	1	326	2.0e-51	196	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
638996693	235	18.27	33	227	4	200	3.0e-14	72.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638996694	532	26.74	3	516	34	549	7.0e-62	232	COG0747	ABC-type transport system, periplasmic component	556
638996695	324	35.91	1	323	2	314	7.0e-72	264	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
638996696	328	36.36	33	304	16	287	8.0e-54	204	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
638996697	330	50.47	8	324	1	316	7.0e-111	393	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
638996698	335	39.75	19	334	4	316	1.0e-83	303	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
638996698	335	39.94	14	325	2	309	3.0e-97	348	COG4608	ABC-type oligopeptide transport system, ATPase component	309
638996699	722	21.15	11	337	6	263	4.0e-20	94	COG2273	Beta-glucanase, GH16 family	355
638996700	414	15.47	1	413	3	432	4.0e-13	69.3	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
638996702	333	38.14	2	331	1	333	4.0e-86	311	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
638996709	325	22.05	3	321	2	308	6.0e-35	141	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638996710	454	28.38	11	450	13	451	1.0e-55	210	COG0534	Na+-driven multidrug efflux pump	455
638996711	334	44.31	2	333	1	333	2.0e-89	322	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
638996712	687	29.28	285	687	9	408	4.0e-41	163	COG0840	Methyl-accepting chemotaxis protein	408
638996713	816	34.02	6	816	271	1054	0.0e+00	714	COG3459	Cellobiose phosphorylase	1056
638996714	414	21.49	16	378	14	376	3.0e-20	93.1	COG2942	Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family	388
638996715	682	53.15	1	681	6	683	0.0e+00	841	COG0339	Zn-dependent oligopeptidase	683
638996717	239	58.23	1	236	8	229	2.0e-75	275	COG0689	Ribonuclease PH	230
638996718	287	49.66	1	287	1	290	1.0e-72	266	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
638996727	491	30.34	47	479	22	453	2.0e-60	227	COG0534	Na+-driven multidrug efflux pump	455
638996728	298	32.34	37	295	8	253	1.0e-34	140	COG0584	Glycerophosphoryl diester phosphodiesterase	257
638996729	207	51.32	4	192	1	188	1.0e-68	252	COG0194	Guanylate kinase	191
638996730	69	60.61	1	65	1	66	1.0e-12	64.9	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
638996731	700	43	1	700	6	701	0.0e+00	800	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
638996732	173	27.22	1	166	1	168	7.0e-11	60.4	COG1495	Disulfide bond formation protein DsbB	170
638996734	232	29.33	3	220	17	240	3.0e-43	168	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
638996735	476	25.21	1	468	1	447	6.0e-62	232	COG0527	Aspartokinase	447
638996736	295	40	120	291	5	179	7.0e-37	147	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638996738	198	22.4	1	183	4	184	2.0e-07	49.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638996739	301	51.46	26	297	1	265	3.0e-83	301	COG0548	Acetylglutamate kinase	265
638996740	851	36.44	401	838	9	455	8.0e-106	378	COG1109	Phosphomannomutase	464
638996741	152	54.17	8	151	6	147	1.0e-50	192	COG0756	dUTPase	148
638996742	405	52.26	6	402	2	391	7.0e-113	400	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
638996743	224	47.32	1	224	1	224	7.0e-77	280	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
638996744	78	66.23	1	76	1	77	2.0e-20	91.1	COG0227	Ribosomal protein L28	77
638996745	52	54	1	50	1	50	9.0e-11	58.3	COG0267	Ribosomal protein L33	50
638996746	271	30.49	28	267	1	241	5.0e-32	131	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
638996747	245	23.11	4	245	1	243	6.0e-24	104	COG1651	Protein-disulfide isomerase	244
638996748	196	37.43	4	190	9	180	4.0e-35	141	COG3803	Uncharacterized conserved protein, DUF924 family	182
638996753	507	24.14	14	128	2	107	5.0e-07	49.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
638996755	162	54.94	1	162	4	164	5.0e-41	160	COG2862	Uncharacterized membrane protein YqhA	169
638996756	668	29.38	263	667	7	408	5.0e-39	156	COG0840	Methyl-accepting chemotaxis protein	408
638996757	210	50.96	3	210	6	209	2.0e-61	228	COG0572	Uridine kinase	218
638996758	386	55.25	1	386	2	395	0.0e+00	478	COG0126	3-phosphoglycerate kinase	395
638996759	358	35	17	354	5	282	2.0e-85	309	COG0191	Fructose/tagatose bisphosphate aldolase	286
638996760	560	39.43	380	550	7	181	5.0e-39	156	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638996761	459	25.3	150	436	39	361	3.0e-23	103	COG1680	CubicO group peptidase, beta-lactamase class C family	390
638996762	134	24.19	12	125	16	137	4.0e-06	44	COG3223	Phosphate starvation-inducible membrane PsiE (function unknown)	138
638996764	560	30.33	172	560	25	408	5.0e-44	172	COG0840	Methyl-accepting chemotaxis protein	408
638996765	220	24.88	5	220	9	211	4.0e-15	75	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
638996766	409	18.67	10	402	30	427	5.0e-14	72.4	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
638996767	551	29.91	26	531	40	601	4.0e-101	362	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
638996768	428	26.91	106	424	11	332	1.0e-29	124	COG0642	Signal transduction histidine kinase	336
638996769	234	43.1	4	232	1	229	2.0e-57	215	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638996771	363	25.27	164	343	60	240	2.0e-17	83.8	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
638996772	342	30.03	7	330	1	324	2.0e-43	169	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
638996773	187	24.72	1	177	6	182	5.0e-09	54.1	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
638996776	94	36.17	1	94	10	103	1.0e-10	58.1	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
638996777	112	71.43	1	112	1	112	1.0e-39	154	COG0347	Nitrogen regulatory protein PII	112
638996778	406	37.32	11	403	3	405	7.0e-80	291	COG0004	Ammonia channel protein AmtB	409
638996780	331	28.85	1	247	9	256	3.0e-27	115	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
638996781	156	38.46	18	153	55	197	1.0e-22	98.9	COG0791	Cell wall-associated hydrolase, NlpC family	197
638996782	182	34.81	1	171	1	177	4.0e-19	87.7	COG4094	Uncharacterized membrane protein	219
638996783	647	45.7	67	623	1	525	0.0e+00	677	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
638996784	182	36.41	1	182	41	215	1.0e-25	109	COG3122	Uncharacterized conserved protein YaiL, DUF2058 family	215
638996785	412	36.85	1	411	2	425	2.0e-109	389	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
638996787	218	37.38	3	212	2	208	5.0e-39	154	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
638996790	1163	24.27	4	468	6	464	6.0e-52	200	COG0591	Na+/proline symporter	493
638996790	1163	29.96	769	1031	71	334	3.0e-31	131	COG0642	Signal transduction histidine kinase	336
638996791	338	44.44	13	334	4	320	2.0e-100	359	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
638996792	98	41.56	20	96	19	95	2.0e-16	77.7	COG5453	Uncharacterized protein	96
638996793	292	39.66	1	282	1	286	1.0e-69	256	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
638996794	134	49.48	4	100	3	99	1.0e-21	95.8	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
638996795	232	22.42	21	230	4	225	1.0e-17	83.4	COG1011	FMN phosphatase YigB, HAD superfamily	229
638996796	281	43.8	24	269	14	268	5.0e-56	211	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
638996797	292	28.46	10	273	13	272	1.0e-46	180	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
638996798	414	38.23	22	410	1	392	5.0e-91	328	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
638996800	220	33.02	1	212	5	201	3.0e-42	165	COG0560	Phosphoserine phosphatase	212
638996801	163	20.14	13	152	17	151	5.0e-09	54.2	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
638996802	761	44.4	5	752	2	750	0.0e+00	737	COG3605	Signal transduction protein containing GAF and PtsI domains	756
638996803	300	51.83	1	300	1	298	4.0e-105	374	COG4989	Predicted oxidoreductase	298
638996805	427	63.92	5	427	7	429	0.0e+00	612	COG0001	Glutamate-1-semialdehyde aminotransferase	432
638996806	873	30.57	13	868	39	889	2.0e-108	387	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
638996807	141	50.69	1	141	6	149	2.0e-40	158	COG1981	Uncharacterized membrane protein	149
638996808	572	30.24	19	419	19	428	7.0e-50	192	COG0038	H+/Cl- antiporter ClcA	443
638996810	144	24.79	13	133	24	140	9.0e-16	76.1	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
638996811	114	49.06	8	113	4	109	7.0e-35	138	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
638996812	157	25.71	52	156	11	109	3.0e-06	44.9	COG1416	Intracellular sulfur oxidation protein, DsrE/DsrF family	112
638996813	432	31.78	178	386	48	257	7.0e-30	125	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
638996814	411	40.25	15	410	1	400	4.0e-105	374	COG0162	Tyrosyl-tRNA synthetase	401
638996821	194	29.94	34	186	40	193	7.0e-21	93.9	COG3145	Alkylated DNA repair dioxygenase AlkB	194
638996823	289	53.68	1	284	1	285	1.0e-97	349	COG1946	Acyl-CoA thioesterase	289
638996824	201	47.21	1	197	2	187	2.0e-62	231	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
638996825	412	34.3	1	373	23	387	6.0e-75	275	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
638996828	190	30.93	43	139	1	96	2.0e-08	52.4	COG3018	Uncharacterized protein	115
638996831	262	49.22	1	257	1	254	8.0e-87	313	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
638996832	331	53.52	1	326	3	329	1.0e-108	386	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
638996833	404	20.59	98	403	18	305	1.0e-10	61.3	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
638996834	818	22.18	79	793	64	761	6.0e-58	219	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
638996835	268	29.69	71	262	1	174	2.0e-22	99.6	COG1076	DnaJ-domain-containing proteins 1	174
638996836	799	35.78	1	799	271	1054	0.0e+00	789	COG3459	Cellobiose phosphorylase	1056
638996837	470	32.34	1	469	7	458	2.0e-92	333	COG1109	Phosphomannomutase	464
638996838	404	18.55	32	402	30	387	8.0e-09	55.2	COG2814	Predicted arabinose efflux permease, MFS family	394
638996839	232	48	10	232	2	226	2.0e-69	255	COG0220	tRNA G46 methylase TrmB	227
638996840	123	43.09	1	123	1	123	2.0e-16	77.6	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
638996841	290	36.46	15	285	63	330	8.0e-61	227	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
638996842	320	32.39	32	315	11	292	3.0e-45	176	COG2177	Cell division protein FtsX	297
638996843	228	57.87	1	216	1	216	1.0e-84	306	COG2884	ABC-type ATPase involved in cell division	223
638996844	330	55.21	7	326	15	340	2.0e-110	392	COG0552	Signal recognition particle GTPase	340
638996846	169	38.95	1	164	14	185	2.0e-39	155	COG0742	16S rRNA G966 N2-methylase RsmD	187
638996847	477	31.81	19	450	42	468	3.0e-86	312	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638996848	161	60.38	1	159	1	159	4.0e-64	237	COG0669	Phosphopantetheine adenylyltransferase	159
638996850	346	25.6	139	345	2	168	6.0e-26	111	COG0516	IMP dehydrogenase/GMP reductase	170
638996851	207	18.13	14	202	1	190	3.0e-10	58.5	COG0558	Phosphatidylglycerophosphate synthase	192
638996852	213	46.7	1	212	2	213	2.0e-55	208	COG4136	ABC-type uncharacterized transport system YnjBCD, ATPase component	213
638996853	583	38.74	26	580	7	549	5.0e-101	362	COG4135	ABC-type uncharacterized transport system YnjBCD, permease component	551
638996854	397	43.18	1	395	4	380	5.0e-88	318	COG4134	ABC-type uncharacterized transport system YnjBCD, periplasmic component	384
638996855	945	41.98	29	925	57	948	0.0e+00	761	COG1391	Glutamine synthetase adenylyltransferase	963
638996856	331	29.7	22	321	5	284	1.0e-43	170	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
638996857	104	44.44	2	100	1	97	1.0e-18	84.8	COG1534	RNA-binding protein YhbY	97
638996858	206	57.43	5	206	2	203	4.0e-72	264	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
638996859	643	58.1	6	602	1	596	0.0e+00	771	COG0465	ATP-dependent Zn proteases	596
638996860	270	50.37	1	265	11	274	6.0e-72	264	COG0294	Dihydropteroate synthase	274
638996861	446	43.67	5	446	7	462	6.0e-117	414	COG1109	Phosphomannomutase	464
638996862	249	53.6	1	247	1	247	4.0e-77	280	COG0149	Triosephosphate isomerase	251
638996863	115	48.78	5	86	3	83	7.0e-15	72.5	COG1314	Preprotein translocase subunit SecG	86
638996866	155	51.35	7	154	6	153	2.0e-41	161	COG0779	Ribosome maturation factor RimP	153
638996867	503	48.98	167	361	1	190	6.0e-47	182	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
638996868	851	59.33	347	851	1	509	0.0e+00	641	COG0532	Translation initiation factor IF-2, a GTPase	509
638996869	137	42.28	4	126	3	117	1.0e-26	112	COG0858	Ribosome-binding factor A	118
638996870	305	37.66	1	304	2	271	2.0e-62	232	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
638996871	89	58.43	1	89	1	89	3.0e-26	110	COG0184	Ribosomal protein S15P/S13E	89
638996872	706	59.57	4	698	2	692	0.0e+00	948	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
638996873	843	46.16	6	834	3	795	0.0e+00	846	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
638996874	334	46.5	2	330	26	354	7.0e-94	337	COG4972	Tfp pilus assembly protein, ATPase PilM	354
638996875	190	27.37	1	190	4	193	3.0e-25	108	COG3166	Tfp pilus assembly protein PilN	206
638996876	211	40.61	14	210	5	196	9.0e-48	183	COG3167	Tfp pilus assembly protein PilO	211
638996877	182	36.93	4	178	1	167	7.0e-31	127	COG3168	Tfp pilus assembly protein PilP	170
638996878	709	29.8	19	702	23	707	2.0e-97	350	COG4796	Type II secretory pathway, component HofQ	709
638996879	160	50	1	158	11	167	2.0e-48	184	COG0703	Shikimate kinase	172
638996880	360	56.67	1	359	1	359	5.0e-130	457	COG0337	3-dehydroquinate synthetase	360
638996882	1481	61.38	699	1173	8	485	0.0e+00	654	COG0069	Glutamate synthase domain 2	485
638996883	472	45.71	26	470	1	450	0.0e+00	483	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
638996885	195	27.74	1	153	1	153	3.0e-14	71.9	COG3124	Acyl carrier protein phosphodiesterase	193
638996886	354	54.96	1	352	2	352	0.0e+00	460	COG0407	Uroporphyrinogen-III decarboxylase	352
638996887	790	26.49	8	777	2	752	4.0e-75	276	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
638996888	747	44.64	1	741	1	742	0.0e+00	767	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
638996890	419	22.17	8	412	17	427	6.0e-25	108	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
638996891	313	53.07	5	312	4	304	5.0e-105	374	COG0181	Porphobilinogen deaminase	307
638996892	246	23.36	1	240	1	241	1.0e-21	96.7	COG1587	Uroporphyrinogen-III synthase	248
638996893	373	25.94	18	370	1	372	7.0e-21	95.1	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
638996894	392	20.97	5	377	1	386	2.0e-12	67.2	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
638996895	161	52.35	9	156	8	156	1.0e-48	185	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
638996896	415	24.05	5	414	14	429	5.0e-30	125	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
638996897	306	33.22	6	306	3	293	7.0e-51	194	COG1175	ABC-type sugar transport system, permease component	295
638996898	293	35.36	15	292	10	281	3.0e-56	212	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
638996899	369	53.85	1	364	1	338	7.0e-124	437	COG3839	ABC-type sugar transport system, ATPase component	338
638996901	694	27.92	525	673	7	159	8.0e-16	79.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638996903	464	60.7	4	461	2	459	0.0e+00	646	COG0165	Argininosuccinate lyase	459
638996905	238	36.93	1	237	2	241	9.0e-42	163	COG3279	DNA-binding response regulator, LytR/AlgR family	244
638996907	425	22.08	53	368	28	344	2.0e-39	157	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
638996908	518	50.97	1	513	14	528	0.0e+00	643	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
638996909	313	38.01	1	313	3	317	8.0e-65	240	COG0611	Thiamine monophosphate kinase	317
638996910	158	52.08	14	154	17	159	2.0e-31	128	COG1267	Phosphatidylglycerophosphatase A	160
638996914	747	38.2	1	744	1	750	0.0e+00	616	COG3605	Signal transduction protein containing GAF and PtsI domains	756
638996917	392	17.22	4	388	11	394	3.0e-11	63.3	COG2814	Predicted arabinose efflux permease, MFS family	394
638996920	989	33.06	520	989	29	481	6.0e-72	266	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
638996922	214	23.13	70	214	40	186	1.0e-06	47	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
638996923	201	20.24	21	183	4	171	4.0e-08	51.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638996924	127	23.62	1	127	11	135	2.0e-13	68	COG3439	Uncharacterized conserved protein, DUF302 family	137
638996925	184	30.23	12	176	1	171	7.0e-23	100	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638996926	470	27.05	202	469	8	282	9.0e-19	88.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638996931	294	38.16	13	287	17	312	6.0e-64	238	COG0627	S-formylglutathione hydrolase FrmB	316
638996932	374	68.02	6	374	1	366	0.0e+00	576	COG1062	Zn-dependent alcohol dehydrogenase	366
638996933	306	30.33	5	296	1	296	2.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
638996934	304	29.33	1	285	6	303	1.0e-38	154	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
638996937	349	32.46	8	348	1	333	7.0e-55	207	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
638996938	418	21.56	1	418	7	433	8.0e-37	148	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
638996939	310	44.13	31	310	12	291	3.0e-63	235	COG1175	ABC-type sugar transport system, permease component	295
638996940	297	41.73	21	296	5	281	4.0e-60	225	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
638996942	398	18.75	1	397	1	425	4.0e-28	119	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
638996948	950	20.33	2	475	91	506	6.0e-24	106	COG3227	Zn-dependent metalloprotease	507
638996949	1408	23.66	4	522	9	481	6.0e-37	150	COG3227	Zn-dependent metalloprotease	507
638996950	976	29.36	349	691	2	329	3.0e-38	154	COG0642	Signal transduction histidine kinase	336
638996952	287	37.5	8	251	5	251	3.0e-58	218	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
638996954	333	29.28	28	329	15	315	2.0e-42	166	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
638996955	472	27.96	9	284	4	275	2.0e-24	107	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
638996956	354	20.19	61	330	57	369	2.0e-21	96.6	COG1680	CubicO group peptidase, beta-lactamase class C family	390
638996959	193	38.14	1	186	1	193	2.0e-28	118	COG3644	Uncharacterized protein	194
638996960	467	28.79	1	451	1	449	1.0e-46	181	COG0534	Na+-driven multidrug efflux pump	455
638996961	441	27.13	11	438	6	409	3.0e-58	219	COG2124	Cytochrome P450	411
638996962	156	26.67	13	143	10	135	1.0e-09	56.2	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
638996963	276	24.44	34	241	48	272	4.0e-28	118	COG3868	Uncharacterized protein	306
638996964	241	29.86	28	236	37	253	2.0e-31	128	COG5429	Uncharacterized protein	261
638996965	274	31.82	5	261	5	264	4.0e-49	188	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
638996968	115	33.96	8	112	5	104	8.0e-13	65.8	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
638996969	845	45.8	3	808	5	793	0.0e+00	907	COG1251	NAD(P)H-nitrite reductase, large subunit	793
638996971	272	32.53	1	243	15	252	1.0e-34	139	COG2116	Formate/nitrite transporter FocA, FNT family	265
638996972	605	23.41	20	252	12	255	1.0e-27	118	COG0631	Serine/threonine protein phosphatase PrpC	262
638996972	605	23.67	281	544	1	280	7.0e-26	112	COG0515	Serine/threonine protein kinase	384
638996973	146	45.27	1	146	4	151	2.0e-43	167	COG1513	Cyanate lyase	151
638996974	334	26.75	5	326	2	302	4.0e-42	165	COG2215	ABC-type nickel/cobalt efflux system, permease component RcnA	303
638996975	370	34.68	1	370	2	317	1.0e-65	244	COG4531	ABC-type Zn2+ transport system, periplasmic component/surface adhesin	318
638996976	209	40.4	3	181	27	223	1.0e-49	189	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
638996977	284	41.92	1	259	9	268	2.0e-44	172	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
638996978	401	36.17	6	376	1	323	2.0e-85	309	COG0523	GTPase, G3E family	323
638996980	161	30.5	19	159	8	142	2.0e-14	72.3	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
638996981	334	26.96	11	333	1	321	2.0e-48	186	COG0523	GTPase, G3E family	323
638996985	553	40.61	1	545	2	550	0.0e+00	491	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
638996986	309	28.87	8	293	2	290	2.0e-33	136	COG0583	DNA-binding transcriptional regulator, LysR family	297
638996987	284	34.53	1	270	2	275	7.0e-29	121	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
638996988	819	32.74	144	477	31	353	8.0e-50	192	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638996989	331	40	6	326	7	339	4.0e-61	228	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
638996990	456	45.68	7	447	4	454	2.0e-123	436	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
638996991	185	35.59	1	176	2	176	4.0e-35	140	COG1510	DNA-binding transcriptional regulator GbsR, MarR family	177
638996992	300	27.36	1	295	1	290	5.0e-06	45.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
638996994	1593	32.79	780	1086	46	336	2.0e-42	168	COG0642	Signal transduction histidine kinase	336
638996996	269	20.35	2	268	1	282	3.0e-15	75.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638997003	189	41.48	7	182	4	178	4.0e-21	94.5	COG1268	Biotin transporter BioY	184
638997004	200	26.61	1	195	2	212	6.0e-07	47.7	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
638997005	233	40.69	3	224	1	231	5.0e-49	187	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
638997006	178	30.95	9	175	12	171	5.0e-20	90.7	COG3153	Predicted N-acetyltransferase YhbS	171
638997007	274	28.12	1	208	2	225	1.0e-25	110	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
638997008	140	24.79	17	133	3	119	1.0e-07	48.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
638997011	272	48.22	14	266	2	250	6.0e-84	304	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
638997012	334	29.85	1	333	3	297	2.0e-36	146	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
638997013	350	35.8	20	341	3	313	7.0e-45	174	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
638997014	398	22.49	27	362	6	332	3.0e-24	106	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
638997015	263	49.79	1	240	3	237	3.0e-79	288	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
638997016	600	34.39	5	597	16	607	0.0e+00	468	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
638997018	138	18.98	5	128	3	138	9.0e-07	46.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
638997021	269	21.34	2	227	29	274	1.0e-09	57	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
638997023	183	26.35	3	168	13	179	9.0e-12	63.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638997026	309	28.05	3	300	2	297	1.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
638997027	181	30.51	4	171	1	176	7.0e-14	70.2	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
638997028	191	25.33	37	177	28	172	1.0e-11	62.7	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
638997029	354	43.09	168	348	1	179	3.0e-39	156	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638997030	176	31.25	5	176	4	179	6.0e-25	107	COG3038	Cytochrome b561	181
638997032	579	30.24	110	439	4	334	3.0e-39	157	COG0642	Signal transduction histidine kinase	336
638997033	211	31.4	11	211	4	209	6.0e-34	137	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
638997035	199	28.32	21	186	16	186	5.0e-19	87.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638997036	580	38.86	5	577	20	607	0.0e+00	517	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
638997038	134	35.34	1	133	3	133	2.0e-19	88.5	COG3791	Uncharacterized conserved protein	133
638997039	409	18.75	22	318	26	317	7.0e-15	75.2	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
638997040	577	53.78	118	235	3	121	5.0e-34	139	COG1445	Phosphotransferase system fructose-specific component IIB	122
638997040	577	62.68	238	574	1	341	9.0e-101	361	COG1299	Phosphotransferase system, fructose-specific IIC component	343
638997041	317	42.81	5	309	2	307	4.0e-84	304	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
638997042	965	44.17	411	960	2	565	0.0e+00	552	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
638997042	965	50	10	151	1	142	1.0e-42	169	COG4668	Mannitol/fructose-specific phosphotransferase system, IIA domain	142
638997043	332	31.53	1	330	1	327	2.0e-55	209	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
638997045	583	37.28	25	571	16	547	5.0e-109	388	COG0659	Sulfate permease or related transporter, MFS superfamily	554
638997050	120	20.79	18	116	25	125	2.0e-13	68.1	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
638997054	411	46.24	239	409	10	181	2.0e-41	163	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638997055	318	18.4	1	275	5	289	2.0e-19	89.9	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
638997057	397	35.01	3	397	5	387	6.0e-84	304	COG2942	Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family	388
638997058	320	28.34	51	318	25	314	8.0e-33	134	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
638997059	240	46.88	173	236	2	65	4.0e-13	68.5	COG2771	DNA-binding transcriptional regulator, CsgD family	65
638997060	193	38.38	9	192	8	190	2.0e-43	168	COG3916	N-acyl-L-homoserine lactone synthetase	209
638997062	635	21.36	254	634	72	435	1.0e-15	78.4	COG4097	Predicted ferric reductase	438
638997063	285	31.48	47	254	4	200	6.0e-26	111	COG0625	Glutathione S-transferase	211
638997064	228	25.66	1	224	7	227	2.0e-26	112	COG1011	FMN phosphatase YigB, HAD superfamily	229
638997066	302	28.08	4	291	2	289	1.0e-37	150	COG0583	DNA-binding transcriptional regulator, LysR family	297
638997067	259	30.37	1	256	1	266	9.0e-49	187	COG1018	Ferredoxin-NADP reductase	266
638997068	763	58.36	427	755	2	328	3.0e-119	423	COG0620	Methionine synthase II (cobalamin-independent)	330
638997069	305	27.05	2	291	1	288	4.0e-32	132	COG0583	DNA-binding transcriptional regulator, LysR family	297
638997071	228	46.15	45	225	4	182	1.0e-42	166	COG3703	Cation transport regulator ChaC	190
638997073	170	31.18	1	167	9	178	9.0e-24	103	COG2320	GrpB domain, predicted nucleotidyltransferase, UPF0157 family	185
638997074	114	21.51	19	111	1	89	1.0e-11	61.8	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
638997075	628	35.66	1	409	4	391	3.0e-57	217	COG0475	Kef-type K+ transport system, membrane component KefB	397
638997077	370	27.64	16	366	3	367	2.0e-24	107	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
638997078	1024	25.76	2	1013	1	1007	0.0e+00	675	COG0841	Multidrug efflux pump subunit AcrB	1009
638997080	780	43.31	518	771	1	253	4.0e-67	249	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
638997083	319	41.21	1	312	1	310	2.0e-71	262	COG0039	Malate/lactate dehydrogenase	313
638997087	368	24.36	1	347	2	305	4.0e-43	168	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
638997090	205	37.31	6	204	9	208	5.0e-22	97.6	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
638997091	392	18.08	35	383	41	386	8.0e-11	61.8	COG2814	Predicted arabinose efflux permease, MFS family	394
638997092	496	32.45	160	496	95	344	3.0e-47	183	COG3866	Pectate lyase	345
638997093	1026	35.73	284	769	13	425	1.0e-103	371	COG3325	Chitinase, GH18 family	441
638997094	296	27.8	4	291	1	292	1.0e-36	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
638997096	303	31.67	19	299	39	309	2.0e-38	153	COG0385	Predicted Na+-dependent transporter	319
638997097	265	19.91	40	252	40	226	7.0e-09	54.5	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
638997098	180	28.71	5	104	13	113	2.0e-13	69.5	COG1695	DNA-binding transcriptional regulator, PadR family	138
638997100	283	32.52	161	283	3	125	3.0e-19	89.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638997104	459	35.08	8	459	2	456	5.0e-81	295	COG0277	FAD/FMN-containing dehydrogenase	459
638997105	278	49.1	2	278	1	279	3.0e-91	328	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
638997106	256	29.13	3	254	7	258	5.0e-35	141	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
638997107	263	45.24	7	258	6	248	1.0e-70	260	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
638997108	336	22.88	8	322	13	324	9.0e-22	98	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
638997110	204	34.13	1	204	1	208	1.0e-25	109	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
638997114	257	28.34	4	238	2	234	4.0e-38	151	COG1387	Histidinol phosphatase or related hydrolase of the PHP family	237
638997117	78	42.65	6	73	2	69	8.0e-12	61.9	COG3205	Uncharacterized membrane protein	72
638997119	152	26.49	1	148	1	148	2.0e-19	88.5	COG1959	DNA-binding transcriptional regulator, IscR family	150
638997120	481	21.3	2	359	3	381	2.0e-13	71.4	COG2814	Predicted arabinose efflux permease, MFS family	394
638997122	224	27.05	10	204	4	196	6.0e-13	67.9	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
638997128	254	28.24	34	245	56	310	6.0e-27	114	COG0627	S-formylglutathione hydrolase FrmB	316
638997129	241	24.1	1	241	5	253	5.0e-07	48.1	COG0730	Uncharacterized membrane protein YfcA	258
638997130	280	27.01	1	272	2	262	8.0e-39	154	COG0300	Short-chain dehydrogenase	265
638997131	314	23.33	6	314	2	314	8.0e-28	118	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638997132	305	30.6	16	296	39	309	1.0e-38	153	COG0385	Predicted Na+-dependent transporter	319
638997133	445	23.56	5	397	12	436	3.0e-38	153	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
638997134	341	31.2	221	341	1	125	6.0e-15	75.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638997137	450	35.81	8	446	6	443	1.0e-111	397	COG0595	mRNA degradation ribonuclease J1/J2	555
638997139	280	21.01	133	261	18	155	6.0e-07	48.1	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
638997140	617	27.03	29	550	12	495	2.0e-56	214	COG1283	Na+/phosphate symporter	533
638997142	89	48.31	1	89	1	89	2.0e-28	116	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
638997143	353	49.12	8	346	11	337	5.0e-105	374	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
638997145	615	54	1	608	8	570	0.0e+00	789	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
638997146	330	44.71	8	330	1	316	1.0e-97	350	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
638997146	330	53.63	5	321	1	309	1.0e-122	433	COG4608	ABC-type oligopeptide transport system, ATPase component	309
638997147	322	56.43	3	318	1	316	4.0e-125	441	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
638997148	309	41.18	21	309	5	287	3.0e-65	242	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
638997149	307	43.53	1	307	1	315	1.0e-75	276	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
638997151	558	35.05	1	557	5	562	1.0e-112	400	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
638997153	206	53.53	38	206	3	170	4.0e-68	251	COG0225	Peptide methionine sulfoxide reductase MsrA	174
638997158	393	36.39	1	393	1	392	1.0e-68	254	COG0183	Acetyl-CoA acetyltransferase	392
638997159	424	27.36	10	421	4	409	3.0e-51	196	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
638997160	212	43.54	1	208	5	213	6.0e-55	207	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
638997161	231	45.79	1	214	2	215	4.0e-57	214	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
638997162	446	40	12	436	25	445	9.0e-120	424	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
638997163	317	25.17	15	297	2	283	1.0e-26	114	COG0583	DNA-binding transcriptional regulator, LysR family	297
638997164	403	23.88	5	375	60	476	3.0e-33	136	COG1574	Predicted amidohydrolase YtcJ	535
638997165	164	21.82	1	134	4	168	8.0e-14	69.9	COG1335	Nicotinamidase-related amidase	205
638997166	483	33.81	1	474	4	464	1.0e-79	291	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
638997168	557	25.65	25	549	11	526	9.0e-52	198	COG1315	Uncharacterized conserved protein, DUF342 family	543
638997169	211	50.53	26	211	6	190	5.0e-60	224	COG0302	GTP cyclohydrolase I	195
638997170	448	35.43	2	442	31	473	3.0e-94	339	COG0513	Superfamily II DNA and RNA helicase	513
638997175	545	30	161	544	24	436	1.0e-50	194	COG3325	Chitinase, GH18 family	441
638997176	310	45.95	1	295	2	295	1.0e-93	336	COG1242	Radical SAM superfamily enzyme	312
638997177	693	28.67	3	287	58	332	1.0e-29	125	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
638997178	254	27	8	251	19	279	1.0e-19	90.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638997180	278	28.1	1	262	1	273	2.0e-36	146	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
638997181	280	28.47	1	279	11	292	6.0e-38	151	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
638997182	67	42.42	1	66	26	91	1.0e-11	61.4	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
638997184	534	52.08	1	530	2	509	0.0e+00	643	COG0029	Aspartate oxidase	518
638997185	203	36.67	8	187	2	175	3.0e-30	125	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638997187	317	27.99	4	316	9	320	3.0e-39	155	COG3026	Negative regulator of sigma E activity	320
638997188	162	35.76	5	153	1	147	4.0e-23	101	COG3086	Positive regulator of sigma E activity	150
638997189	448	44.77	13	354	27	345	5.0e-69	255	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
638997190	600	67.22	1	600	2	602	0.0e+00	1027	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
638997191	367	21.47	141	317	19	163	1.0e-11	64.2	COG0681	Signal peptidase I	166
638997193	219	53.15	3	219	13	233	1.0e-66	246	COG0571	dsRNA-specific ribonuclease	235
638997194	302	53.72	9	302	4	298	9.0e-111	393	COG1159	GTPase Era, involved in 16S rRNA processing	298
638997196	123	46.72	1	122	2	123	1.0e-32	131	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
638997197	951	34.96	250	514	82	335	5.0e-41	163	COG0642	Signal transduction histidine kinase	336
638997198	297	47.33	4	292	2	300	5.0e-98	350	COG0031	Cysteine synthase	300
638997199	414	29.09	14	406	3	432	3.0e-80	292	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
638997200	744	51.1	11	740	3	701	0.0e+00	822	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
638997203	378	27.98	41	373	3	320	2.0e-59	223	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
638997206	407	31.38	4	235	21	257	6.0e-25	109	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
638997207	152	31.79	9	150	8	154	5.0e-14	70.4	COG4539	Uncharacterized membrane protein YGL010W	180
638997208	239	44.77	1	239	1	239	2.0e-71	262	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
638997210	431	47.14	5	421	1	417	3.0e-128	451	COG4536	Mg2+ and Co2+ transporter CorB, contains DUF21, CBS pair, and CorC-HlyC domains	423
638997211	263	33.85	5	260	8	263	3.0e-32	132	COG4137	ABC-type uncharacterized transport system, permease component	265
638997212	473	59.47	1	454	1	451	0.0e+00	591	COG0541	Signal recognition particle GTPase	451
638997213	83	59.76	1	82	1	81	1.0e-24	104	COG0228	Ribosomal protein S16	87
638997214	177	41.38	5	177	3	172	1.0e-41	163	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
638997215	258	54.55	11	251	1	240	1.0e-103	369	COG0336	tRNA G37 N-methylase TrmD	240
638997216	121	67.26	4	116	2	114	8.0e-41	158	COG0335	Ribosomal protein L19	115
638997217	432	49.39	1	317	1	328	5.0e-98	351	COG0460	Homoserine dehydrogenase	333
638997218	464	30.19	1	461	1	411	5.0e-97	348	COG0498	Threonine synthase	411
638997219	573	40.74	42	550	1	491	4.0e-107	382	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
638997221	280	64.02	43	280	1	239	1.0e-96	346	COG1186	Protein chain release factor B	239
638997222	510	56.02	19	507	9	502	0.0e+00	666	COG1190	Lysyl-tRNA synthetase (class II)	502
638997223	196	26.17	45	190	35	170	8.0e-11	60.4	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
638997225	225	44.1	1	223	1	228	4.0e-58	217	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638997226	448	25.16	152	448	21	330	7.0e-26	112	COG0642	Signal transduction histidine kinase	336
638997228	239	27.04	1	231	1	220	4.0e-30	125	COG1451	Predicted metal-dependent hydrolase	223
638997229	82	57.75	4	74	1	71	1.0e-19	87.7	COG3530	Uncharacterized conserved protein, DUF3820 family	71
638997231	374	39.73	3	366	6	380	1.0e-95	343	COG1168	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	388
638997232	282	55.97	8	275	1	263	4.0e-99	354	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
638997235	270	22.95	7	270	4	284	2.0e-20	92.7	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
638997236	396	59.85	1	396	1	396	0.0e+00	580	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
638997238	674	66.22	1	674	2	662	0.0e+00	1075	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
638997239	345	61.45	1	344	1	344	0.0e+00	504	COG0418	Dihydroorotase	344
638997241	1120	34.82	559	893	2	327	1.0e-48	188	COG0642	Signal transduction histidine kinase	336
638997242	303	50.85	237	295	4	62	4.0e-12	65.8	COG2771	DNA-binding transcriptional regulator, CsgD family	65
638997243	423	64.78	1	423	6	426	0.0e+00	645	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
638997244	345	31.07	5	341	2	305	7.0e-59	221	COG1619	Muramoyltetrapeptide carboxypeptidase LdcA (peptidoglycan recycling)	313
638997245	256	24.11	19	225	5	257	9.0e-17	80.9	COG1234	Ribonuclease BN, tRNA processing enzyme	292
638997246	422	37.55	1	228	3	228	2.0e-43	170	COG3300	MHYT domain, NO-binding membrane sensor	236
638997247	489	31.52	87	447	7	366	2.0e-66	246	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
638997248	537	39.66	249	536	10	297	7.0e-67	248	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
638997249	382	35.87	44	367	20	314	3.0e-49	189	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
638997250	282	62.25	30	278	1	249	2.0e-103	368	COG4674	ABC-type uncharacterized transport system, ATPase component	249
638997251	231	45.11	1	231	3	237	2.0e-78	285	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
638997252	296	35.27	22	294	5	269	4.0e-46	178	COG0829	Urease accessory protein UreH	269
638997253	100	74	1	100	1	100	1.0e-41	161	COG0831	Urease gamma subunit	100
638997254	106	63.73	1	102	1	102	1.0e-41	161	COG0832	Urease beta subunit	106
638997255	569	76.27	2	569	1	568	0.0e+00	1039	COG0804	Urease alpha subunit	568
638997256	147	39.07	1	147	1	151	5.0e-25	106	COG2371	Urease accessory protein UreE	155
638997257	224	33.62	4	224	1	229	2.0e-37	148	COG0830	Urease accessory protein UreF	229
638997258	213	51.98	1	201	9	202	2.0e-63	235	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
638997259	193	38.1	1	165	6	173	1.0e-14	73	COG2370	Hydrogenase/urease accessory protein HupE	201
638997261	545	22.52	62	501	6	400	1.0e-31	131	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
638997263	221	23.5	1	209	1	214	8.0e-24	103	COG1011	FMN phosphatase YigB, HAD superfamily	229
638997264	135	24.74	17	112	4	98	6.0e-18	83.1	COG3791	Uncharacterized conserved protein	133
638997265	113	27.66	1	93	2	95	2.0e-06	44.6	COG1694	NTP pyrophosphatase, house-cleaning of non-canonical NTPs	102
638997266	462	55.49	1	459	2	460	0.0e+00	554	COG1282	NAD/NADP transhydrogenase beta subunit	463
638997267	523	52.02	5	375	2	356	8.0e-107	381	COG3288	NAD/NADP transhydrogenase alpha subunit	356
638997269	364	40.56	1	356	1	359	3.0e-92	332	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
638997270	356	27.78	192	353	21	177	2.0e-15	77.2	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
638997271	887	42.08	7	551	9	442	1.0e-106	381	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
638997276	145	30.89	22	143	2	124	3.0e-13	67.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
638997277	365	54.02	1	359	10	363	4.0e-121	428	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
638997278	190	26.09	7	137	2	137	1.0e-09	56.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
638997279	337	24.77	62	274	44	245	3.0e-32	132	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
638997280	214	34.58	1	210	1	208	4.0e-31	128	COG0625	Glutathione S-transferase	211
638997284	491	22.89	47	363	19	349	6.0e-27	115	COG0840	Methyl-accepting chemotaxis protein	408
638997288	170	32.37	2	167	4	176	5.0e-24	104	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
638997289	160	22.76	12	148	9	150	1.0e-06	46.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
638997290	366	38.82	5	342	2	314	5.0e-81	294	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
638997291	295	30.85	6	294	3	288	4.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
638997292	220	31.67	1	178	1	166	3.0e-32	131	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
638997295	778	27.24	328	637	20	329	2.0e-35	144	COG0642	Signal transduction histidine kinase	336
638997296	200	35.71	3	198	1	209	6.0e-35	140	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
638997297	659	26.19	16	652	3	605	3.0e-77	283	COG3408	Glycogen debranching enzyme (alpha-1,6-glucosidase)	641
638997299	395	47.16	4	388	2	388	1.0e-123	437	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
638997300	340	33.43	1	340	1	350	2.0e-78	285	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
638997301	208	36.41	3	208	2	202	3.0e-29	121	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
638997302	384	35.92	1	384	2	370	1.0e-87	317	COG4637	Predicted ATPase	373
638997303	139	29.79	1	125	12	151	1.0e-11	62.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
638997304	413	16.62	85	404	73	391	7.0e-10	58.7	COG2814	Predicted arabinose efflux permease, MFS family	394
638997308	405	48.91	1	404	2	412	5.0e-123	434	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
638997309	172	36.77	16	168	4	147	1.0e-33	136	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
638997311	150	39.29	1	137	1	140	5.0e-22	97	COG2703	Hemerythrin	144
638997312	151	33.83	1	130	1	133	1.0e-21	95.8	COG2703	Hemerythrin	144
638997313	401	35.92	301	401	4	104	3.0e-15	76.9	COG0607	Rhodanese-related sulfurtransferase	110
638997318	225	19.42	14	217	2	199	2.0e-10	59.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638997319	203	32.83	1	196	3	191	2.0e-24	105	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
638997320	209	34.45	1	209	10	217	2.0e-39	155	COG2345	Predicted transcriptional regulator, ArsR family	218
638997321	269	23.08	7	225	10	235	7.0e-23	101	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
638997323	142	35.25	3	139	20	157	2.0e-13	68.8	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
638997325	426	44.75	1	419	2	439	0.0e+00	498	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
638997326	961	52.59	1	960	1	877	0.0e+00	1180	COG0525	Valyl-tRNA synthetase	877
638997328	140	26.71	1	140	1	143	2.0e-16	78	COG2927	DNA polymerase III, chi subunit	144
638997329	489	41.92	5	487	3	483	0.0e+00	465	COG0260	Leucyl aminopeptidase	485
638997331	103	36.96	12	102	9	100	1.0e-08	51.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
638997333	126	46.28	6	126	2	122	1.0e-27	115	COG0818	Diacylglycerol kinase	123
638997334	784	32.13	8	776	49	841	1.0e-116	414	COG1643	HrpA-like RNA helicase	845
638997337	323	25.89	1	317	19	350	1.0e-45	177	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
638997339	160	52.94	8	160	3	155	2.0e-53	201	COG1225	Peroxiredoxin	157
638997342	1193	19.12	155	1131	170	1133	3.0e-21	98.6	COG1196	Chromosome segregation ATPase	1163
638997343	209	60.48	1	209	2	210	6.0e-74	270	COG0035	Uracil phosphoribosyltransferase	210
638997344	243	40.09	11	240	1	228	1.0e-47	182	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638997345	319	32.97	46	313	21	294	7.0e-51	194	COG2813	16S rRNA G1207 methylase RsmC	300
638997350	233	33.19	3	228	2	220	1.0e-35	143	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
638997351	267	42.54	1	266	4	268	1.0e-55	210	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
638997354	821	35.84	1	814	1	806	0.0e+00	653	COG2937	Glycerol-3-phosphate O-acyltransferase	810
638997355	68	34.38	6	68	9	72	9.0e-07	45.3	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
638997356	153	47.76	85	150	1	67	3.0e-20	91	COG1278	Cold shock protein, CspA family	67
638997359	378	35.18	1	376	11	408	6.0e-79	288	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
638997361	145	34.27	1	143	10	147	2.0e-17	81.9	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
638997363	448	64.8	1	446	2	445	0.0e+00	721	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
638997365	344	24.92	7	318	17	334	2.0e-43	169	COG0687	Spermidine/putrescine-binding periplasmic protein	363
638997367	1014	21.67	561	1014	1	386	4.0e-39	157	COG0247	Fe-S oxidoreductase	388
638997367	1014	32.35	34	535	14	458	7.0e-73	269	COG0277	FAD/FMN-containing dehydrogenase	459
638997369	573	46.34	1	570	1	500	0.0e+00	576	COG0442	Prolyl-tRNA synthetase	500
638997370	138	26.81	1	118	1	138	9.0e-12	62.9	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
638997371	367	45.18	7	361	22	384	1.0e-112	400	COG3146	Predicted N-acyltransferase	387
638997372	141	27.68	20	126	24	134	2.0e-13	68.5	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
638997374	355	20.31	1	317	2	380	3.0e-12	66.6	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
638997375	517	51.16	1	514	1	511	0.0e+00	599	COG3283	Transcriptional regulator of aromatic amino acids metabolism	511
638997376	861	42.75	586	840	3	255	3.0e-65	244	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
638997377	1227	57.88	4	330	1	311	2.0e-115	411	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
638997377	1227	58.17	332	1191	2	842	0.0e+00	1159	COG1410	Methionine synthase I, cobalamin-binding domain	842
638997379	196	31.96	5	101	5	99	4.0e-20	91.4	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
638997379	196	40.23	102	187	1	87	6.0e-21	94.2	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
638997380	533	16.22	226	410	64	244	6.0e-08	52.8	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
638997383	460	52.38	2	457	1	462	0.0e+00	606	COG0114	Fumarate hydratase class II	462
638997385	290	29.03	6	281	12	280	8.0e-53	200	COG0676	D-hexose-6-phosphate mutarotase	287
638997386	281	24.89	13	237	18	247	1.0e-13	70.5	COG3782	Uncharacterized protein	289
638997387	306	43.71	11	295	1	281	2.0e-73	269	COG0061	NAD kinase	281
638997388	86	40.48	1	82	1	84	2.0e-16	77.4	COG3139	Uncharacterized conserved protein YeaC, DUF1315 family	90
638997390	870	34.08	1	863	4	858	0.0e+00	544	COG0308	Aminopeptidase N	859
638997392	386	23.1	55	309	51	350	8.0e-21	95	COG1566	Multidrug resistance efflux pump	352
638997393	236	48.44	4	226	1	225	2.0e-78	285	COG1136	ABC-type lipoprotein export system, ATPase component	226
638997394	403	31.03	19	403	1	419	7.0e-36	145	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
638997399	84	76.19	1	84	1	83	4.0e-29	119	COG0211	Ribosomal protein L27	87
638997400	397	58.54	1	365	1	368	0.0e+00	500	COG0536	GTPase involved in cell partioning and DNA repair	369
638997401	382	53.3	21	382	8	369	3.0e-122	431	COG0263	Glutamate 5-kinase	369
638997402	191	50.8	1	186	1	187	7.0e-72	263	COG2818	3-methyladenine DNA glycosylase Tag	188
638997403	159	32.08	1	159	32	187	2.0e-15	75.1	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
638997404	869	21.59	6	865	2	726	4.0e-80	293	COG1033	Predicted exporter protein, RND superfamily	727
638997405	285	49.12	1	282	1	280	1.0e-86	312	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
638997406	163	44.87	4	156	1	153	8.0e-38	149	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
638997407	328	49.7	1	328	9	332	9.0e-109	386	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
638997408	452	48.43	1	446	1	436	0.0e+00	554	COG0621	tRNA A37 methylthiotransferase MiaB	437
638997409	108	46.3	1	108	1	108	4.0e-33	132	COG4517	Uncharacterized protein	109
638997410	267	41.28	36	252	50	260	4.0e-45	175	COG2992	Uncharacterized FlgJ-related protein	262
638997411	203	43.46	1	190	1	188	3.0e-55	208	COG0307	Riboflavin synthase alpha chain	204
638997412	162	45.7	14	161	6	155	4.0e-40	157	COG2153	Predicted N-acyltransferase, GNAT family	155
638997413	227	36.56	5	226	13	235	2.0e-31	129	COG2186	DNA-binding transcriptional regulator, FadR family	241
638997414	941	22.31	536	919	8	366	1.0e-35	145	COG0247	Fe-S oxidoreductase	388
638997414	941	30.68	9	515	1	456	1.0e-70	262	COG0277	FAD/FMN-containing dehydrogenase	459
638997415	214	27.98	5	213	4	215	4.0e-24	104	COG3806	Anti-sigma factor ChrR, cupin superfamily	216
638997416	193	27.22	12	189	1	176	2.0e-24	105	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638997417	175	41.07	9	175	20	182	1.0e-29	122	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
638997418	452	37.5	15	452	10	448	3.0e-101	362	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
638997419	89	47.73	1	88	1	88	2.0e-19	87.6	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
638997420	289	47.04	7	287	2	286	6.0e-91	327	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
638997421	152	32.64	4	145	2	144	2.0e-22	98.5	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
638997422	99	53	1	98	1	100	1.0e-23	101	COG1544	Ribosome-associated translation inhibitor RaiA	110
638997423	495	48.08	1	494	1	443	0.0e+00	503	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
638997424	241	65.7	1	241	2	243	9.0e-107	379	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
638997425	173	30.59	1	170	4	163	3.0e-18	85	COG1934	Lipopolysaccharide export system protein LptA	173
638997426	190	22.91	14	190	10	185	7.0e-12	63.8	COG3117	Lipopolysaccharide export system protein LptC	188
638997427	323	60.4	7	207	1	202	7.0e-68	250	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
638997428	321	40.51	1	311	8	313	4.0e-47	181	COG0530	Ca2+/Na+ antiporter	320
638997429	215	22.53	3	184	9	185	5.0e-13	68	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
638997430	76	44.59	1	74	1	74	2.0e-16	77.2	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
638997431	420	62.86	1	420	1	420	0.0e+00	614	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
638997432	218	45.45	8	218	3	220	6.0e-51	193	COG0040	ATP phosphoribosyltransferase	290
638997433	435	51.1	27	435	18	423	0.0e+00	512	COG0141	Histidinol dehydrogenase	425
638997434	366	37.82	17	366	3	354	2.0e-78	286	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
638997435	597	25.67	121	551	1	486	7.0e-53	202	COG0366	Glycosidase	505
638997436	360	35.77	9	360	1	346	6.0e-50	191	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
638997437	249	34	3	249	1	250	6.0e-56	210	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
638997438	540	64.35	19	436	1	418	0.0e+00	639	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
638997439	302	36.77	1	302	11	261	1.0e-58	220	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
638997440	159	25.81	10	133	8	128	4.0e-11	61.2	COG3105	Uncharacterized membrane-anchored protein YhcB, DUF1043 family	138
638997441	367	53.02	3	366	10	367	4.0e-129	454	COG1485	Predicted ATPase	367
638997443	353	26	8	353	53	380	3.0e-34	139	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638997449	334	29.25	8	331	15	349	3.0e-31	129	COG0628	Predicted PurR-regulated permease PerM	355
638997451	248	23.81	1	229	1	205	1.0e-15	76.6	COG2135	Putative SOS response-associated peptidase YedK	226
638997452	256	23.14	26	241	16	234	6.0e-14	71.6	COG0510	Thiamine kinase and related kinases	269
638997453	339	48.36	14	339	2	336	1.0e-100	359	COG4143	ABC-type thiamine transport system, periplasmic component	336
638997454	493	27.43	5	492	15	537	1.0e-37	151	COG1178	ABC-type Fe3+ transport system, permease component	540
638997455	214	42.79	1	201	1	201	6.0e-51	193	COG3840	ABC-type thiamine transport system, ATPase component	231
638997456	376	39.04	1	374	2	355	1.0e-68	254	COG3199	Predicted polyphosphate- or ATP-dependent NAD kinase	355
638997457	177	20.37	26	132	5	112	4.0e-07	47.9	COG0824	Acyl-CoA thioesterase FadM	137
638997458	231	38.29	2	223	8	227	1.0e-36	146	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
638997460	450	39.86	49	450	84	485	5.0e-113	401	COG0260	Leucyl aminopeptidase	485
638997461	482	26.07	11	429	43	407	5.0e-49	189	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
638997462	428	16.34	9	427	6	468	8.0e-08	51.9	COG5339	Uncharacterized conserved protein YdgA, DUF945 family	479
638997464	336	40.82	94	333	80	314	1.0e-55	210	COG2829	Outer membrane phospholipase A	317
638997465	307	34.94	12	278	12	278	1.0e-55	210	COG4667	Predicted phospholipase, patatin/cPLA2 family	292
638997467	130	33.04	10	116	19	129	2.0e-14	71.2	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
638997469	214	19.9	1	200	1	202	2.0e-17	82.6	COG0625	Glutathione S-transferase	211
638997471	319	38.31	5	308	1	233	2.0e-62	233	COG0176	Transaldolase	239
638997472	499	42.15	1	493	2	497	1.0e-123	437	COG1070	Sugar (pentulose or hexulose) kinase	502
638997473	443	66.67	1	441	1	438	0.0e+00	691	COG2115	Xylose isomerase	438
638997474	394	29.02	78	393	1	309	5.0e-42	165	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
638997475	371	23.25	4	256	67	328	2.0e-21	97	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
638997476	418	25.53	1	416	7	427	2.0e-34	140	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
638997477	309	33.11	18	309	2	291	8.0e-54	204	COG1175	ABC-type sugar transport system, permease component	295
638997478	296	33.45	19	295	1	281	4.0e-53	201	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
638997479	535	48.52	1	531	17	546	0.0e+00	551	COG3507	Beta-xylosidase	549
638997480	265	39.02	4	245	10	246	6.0e-50	191	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
638997482	150	21.38	1	138	12	154	1.0e-07	49.6	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
638997483	181	39.77	8	179	5	180	1.0e-29	122	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
638997485	254	20.55	5	245	10	247	2.0e-19	89.7	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
638997486	356	40.7	14	356	20	354	1.0e-81	296	COG5621	Predicted secreted hydrolase	354
638997487	834	18.47	136	829	124	827	1.0e-11	65.7	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
638997488	219	44.84	1	219	1	223	3.0e-63	235	COG1136	ABC-type lipoprotein export system, ATPase component	226
638997489	170	39.74	15	164	1	150	2.0e-32	131	COG0782	Transcription elongation factor, GreA/GreB family	151
638997490	665	24.05	264	658	1	387	1.0e-30	128	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
638997490	665	35.08	15	253	7	252	5.0e-56	212	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
638997492	226	25.55	11	226	8	205	2.0e-19	89.6	COG3103	Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family	205
638997493	100	55.1	1	98	1	92	3.0e-23	99	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
638997494	303	36.25	8	258	3	250	5.0e-45	175	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
638997495	206	41.75	2	206	1	205	4.0e-54	204	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
638997496	359	40.25	124	359	1	241	3.0e-47	182	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
638997497	448	50	114	292	9	184	4.0e-42	166	COG1386	Chromosome segregation and condensation protein ScpB	184
638997498	282	46	4	246	1	248	9.0e-69	253	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
638997499	395	48.38	4	393	2	401	0.0e+00	474	COG2081	Predicted flavoprotein YhiN	408
638997501	182	32.77	11	181	8	184	2.0e-23	101	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638997502	343	38.38	76	342	6	271	3.0e-73	269	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
638997503	113	40	1	113	2	115	2.0e-24	104	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
638997504	396	29.21	5	396	4	389	7.0e-67	248	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
638997505	893	44.39	19	892	5	862	0.0e+00	853	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
638997506	258	52.71	1	256	1	255	2.0e-96	345	COG0024	Methionine aminopeptidase	255
638997507	241	58.92	1	241	6	245	2.0e-93	335	COG0052	Ribosomal protein S2	252
638997508	288	54.58	1	286	2	296	2.0e-84	305	COG0264	Translation elongation factor EF-Ts	296
638997509	185	54.05	1	185	3	187	6.0e-56	210	COG0233	Ribosome recycling factor	187
638997510	234	55.75	1	226	20	245	1.0e-80	292	COG0020	Undecaprenyl pyrophosphate synthase	245
638997511	275	34.43	1	272	1	265	2.0e-28	119	COG0575	CDP-diglyceride synthetase	265
638997512	391	56.99	5	389	1	383	0.0e+00	509	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
638997513	448	31.06	1	448	1	374	2.0e-46	179	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
638997514	773	36.76	1	773	11	766	0.0e+00	539	COG4775	Outer membrane protein assembly factor BamA	766
638997515	181	21.08	5	168	4	169	9.0e-07	46.9	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
638997516	345	49.06	23	339	22	338	9.0e-88	317	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
638997517	152	50.34	5	151	2	147	2.0e-41	161	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
638997518	256	55.29	2	256	6	260	4.0e-98	351	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
638997519	381	48.28	4	379	1	379	2.0e-115	409	COG0763	Lipid A disaccharide synthetase	381
638997520	202	60.32	14	199	1	189	5.0e-68	250	COG0164	Ribonuclease HII	199
638997521	1167	48.73	1	1140	1	1119	0.0e+00	1307	COG0587	DNA polymerase III, alpha subunit	1139
638997523	315	65.92	2	315	1	314	0.0e+00	498	COG0825	Acetyl-CoA carboxylase alpha subunit	317
638997525	439	30.85	11	290	2	287	6.0e-43	168	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
638997526	540	64.33	2	540	1	531	0.0e+00	876	COG0504	CTP synthase (UTP-ammonia lyase)	533
638997527	433	67.13	1	432	1	423	0.0e+00	615	COG0148	Enolase	423
638997528	90	40	1	90	24	113	5.0e-12	63	COG2919	Cell division protein FtsB	117
638997529	198	44.39	2	193	36	228	8.0e-45	173	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
638997530	164	59.75	2	160	1	156	7.0e-56	209	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
638997531	347	31.13	17	339	23	401	1.0e-62	233	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
638997532	224	47.78	21	221	5	205	9.0e-55	206	COG2518	Protein-L-isoaspartate O-methyltransferase	209
638997533	275	36.13	1	229	14	239	1.0e-34	139	COG2035	Uncharacterized membrane protein	276
638997535	344	47.67	67	342	64	342	1.0e-75	276	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
638997536	206	32.2	1	203	1	205	3.0e-20	91.9	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
638997537	107	40.91	4	65	5	68	9.0e-08	48.6	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
638997538	862	49.36	6	860	1	843	0.0e+00	935	COG0249	DNA mismatch repair ATPase MutS	843
638997539	160	43.14	4	155	11	162	4.0e-42	163	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
638997540	365	63.64	5	286	2	279	7.0e-88	317	COG0468	RecA/RadA recombinase	279
638997542	868	55.67	1	866	6	879	0.0e+00	1128	COG0013	Alanyl-tRNA synthetase	879
638997543	408	44.59	1	404	1	447	4.0e-115	408	COG0527	Aspartokinase	447
638997544	63	65.52	1	58	1	58	8.0e-19	85.3	COG1551	sRNA-binding carbon storage regulator CsrA	73
638997548	314	31.11	1	310	11	317	4.0e-61	228	COG0042	tRNA-dihydrouridine synthase	323
638997549	79	29.49	2	79	4	79	5.0e-06	42.6	COG3630	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit	84
638997550	599	64.02	3	478	1	471	0.0e+00	728	COG5016	Pyruvate/oxaloacetate carboxyltransferase	472
638997551	376	72.18	1	376	1	375	0.0e+00	486	COG1883	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit	375
638997553	232	20.39	15	219	7	190	1.0e-11	63.7	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
638997556	320	22.4	3	315	20	332	5.0e-32	131	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
638997557	161	30.6	15	148	15	147	3.0e-12	64.6	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
638997558	425	37.04	49	425	5	376	9.0e-68	251	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
638997567	291	27.27	25	289	34	316	4.0e-31	128	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
638997568	286	38.23	1	279	11	303	6.0e-62	231	COG1161	Ribosome biogenesis GTPase A	322
638997569	308	38.54	1	307	1	311	5.0e-69	254	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
638997570	877	28.68	1	633	1	598	3.0e-78	287	COG1042	Acyl-CoA synthetase (NDP forming)	598
638997571	270	43.51	27	260	30	262	2.0e-56	212	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
638997573	233	35.58	4	210	7	213	2.0e-36	146	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
638997574	310	32.57	15	272	1	254	4.0e-51	195	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
638997577	215	37.04	1	205	2	214	1.0e-20	93.4	COG2836	Sulfite exporter TauE/SafE	232
638997578	61	54.17	1	48	1	48	1.0e-10	58.3	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
638997579	795	36.43	98	795	6	710	0.0e+00	570	COG2217	Cation transport ATPase	713
638997580	171	28.83	10	170	4	163	5.0e-18	84	COG3198	Uncharacterized protein	172
638997581	466	38.06	27	405	2	360	4.0e-80	292	COG0348	Polyferredoxin	386
638997582	299	26.72	81	206	4	131	1.0e-13	70.8	COG2010	Cytochrome c, mono- and diheme variants	150
638997583	60	29.63	1	53	5	58	1.0e-05	41.4	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
638997584	202	60.55	3	199	2	219	1.0e-83	302	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
638997585	478	69.75	7	478	4	479	0.0e+00	665	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
638997588	89	45.68	1	81	2	82	1.0e-21	94.9	COG1254	Acylphosphatase	92
638997591	201	22.99	23	196	17	176	2.0e-21	95.4	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
638997592	127	31.09	1	118	1	119	4.0e-15	73.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
638997595	479	26.94	1	238	4	241	3.0e-26	113	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
638997595	479	35.03	280	476	14	208	2.0e-45	177	COG0352	Thiamine monophosphate synthase	211
638997596	261	54.09	1	257	5	260	3.0e-93	334	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
638997597	64	28.79	1	64	3	68	2.0e-06	44	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
638997598	342	22.84	1	333	5	358	7.0e-27	115	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
638997599	628	66.09	141	598	1	432	0.0e+00	758	COG0422	Thiamine biosynthesis protein ThiC	432
638997602	346	25.07	1	337	5	356	3.0e-23	103	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
638997608	144	38.93	1	144	1	146	5.0e-35	140	COG3019	Uncharacterized conserved protein	149
638997609	177	23.81	1	97	1	100	5.0e-06	44.6	COG2863	Cytochrome c553	121
638997610	794	31.25	20	82	8	71	6.0e-06	46.9	COG2608	Copper chaperone CopZ	71
638997610	794	45.39	82	787	3	710	0.0e+00	712	COG2217	Cation transport ATPase	713
638997611	68	44.78	1	64	3	69	8.0e-08	48.8	COG2608	Copper chaperone CopZ	71
638997613	736	40.62	474	727	1	254	8.0e-59	222	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
638997614	433	41.29	1	433	29	473	5.0e-113	401	COG0513	Superfamily II DNA and RNA helicase	513
638997615	676	34.55	1	666	5	687	0.0e+00	543	COG0480	Translation elongation factor EF-G, a GTPase	697
638997616	376	27.11	25	351	36	362	8.0e-32	131	COG1680	CubicO group peptidase, beta-lactamase class C family	390
638997618	200	45.32	1	189	1	203	4.0e-52	197	COG2808	Predicted FMN-binding regulatory protein PaiB	209
638997623	193	17.24	14	157	2	138	5.0e-12	64.5	COG0563	Adenylate kinase or related kinase	178
638997625	236	42.52	11	224	11	223	3.0e-42	165	COG1346	Putative effector of murein hydrolase	230
638997626	115	35.64	3	103	6	106	3.0e-13	67.1	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
638997627	162	56.46	16	162	8	153	2.0e-49	188	COG0691	tmRNA-binding protein	153
638997628	390	41.35	16	382	16	385	1.0e-103	370	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
638997629	422	35.71	1	419	19	447	2.0e-101	363	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
638997630	426	30.91	6	385	2	382	6.0e-68	251	COG0006	Xaa-Pro aminopeptidase	384
638997631	455	42.98	3	455	15	468	9.0e-120	423	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638997633	268	32.3	10	265	16	269	1.0e-32	134	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
638997634	413	25.2	35	398	31	409	2.0e-55	210	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
638997635	181	31.82	1	151	3	178	2.0e-23	102	COG1335	Nicotinamidase-related amidase	205
638997636	306	31.79	16	299	24	323	3.0e-45	175	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
638997641	363	29.52	7	154	6	167	3.0e-13	69.6	COG2357	ppGpp synthetase catalytic domain (RelA/SpoT-type nucleotidyltranferase)	231
638997643	266	18.65	14	255	13	259	3.0e-13	68.9	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
638997644	293	35.81	1	291	2	291	2.0e-46	179	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
638997645	70	40.74	17	70	10	63	1.0e-06	45.3	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
638997646	312	28.43	5	298	1	297	1.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
638997647	458	44.64	1	451	2	463	0.0e+00	502	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638997648	608	39.41	1	603	1	601	0.0e+00	473	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
638997649	729	44.05	141	727	50	642	2.0e-118	420	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
638997650	328	29.47	8	319	2	317	4.0e-50	192	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
638997652	1090	32.44	439	773	6	328	4.0e-40	160	COG0642	Signal transduction histidine kinase	336
638997654	582	18.5	193	555	71	375	6.0e-12	66.3	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
638997656	188	31.54	5	131	11	138	2.0e-09	56	COG1695	DNA-binding transcriptional regulator, PadR family	138
638997657	589	34.14	163	450	54	334	1.0e-42	168	COG0642	Signal transduction histidine kinase	336
638997658	157	28.03	24	155	26	154	3.0e-16	78.1	COG3915	Uncharacterized protein	155
638997660	129	24.22	3	128	2	129	1.0e-16	78.8	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
638997662	323	32.03	71	322	80	311	1.0e-45	177	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
638997664	247	39.44	1	246	2	243	3.0e-54	205	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
638997666	422	52.21	14	420	4	391	0.0e+00	484	COG0448	ADP-glucose pyrophosphorylase	393
638997668	542	30.27	128	540	1	408	8.0e-43	168	COG0840	Methyl-accepting chemotaxis protein	408
638997672	433	30.05	1	429	6	431	4.0e-63	235	COG0415	Deoxyribodipyrimidine photolyase	461
638997675	94	44.58	1	82	2	84	2.0e-12	64.1	COG1888	Uncharacterized protein	97
638997677	392	30.69	6	193	1	189	2.0e-30	126	COG2059	Chromate transport protein ChrA	195
638997679	252	24.79	132	252	1	121	6.0e-21	94.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638997680	1064	37.18	32	452	1	390	9.0e-79	289	COG0506	Proline dehydrogenase	391
638997680	1064	52.98	457	1059	1	591	0.0e+00	772	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
638997681	508	43.61	4	485	1	490	1.0e-86	313	COG0591	Na+/proline symporter	493
638997682	124	21.48	2	121	21	148	1.0e-08	52	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
638997683	283	47.29	4	261	2	247	3.0e-88	318	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
638997684	328	30.3	23	319	7	250	1.0e-39	157	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
638997685	451	24.87	1	372	1	335	6.0e-40	158	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
638997686	909	31.76	14	724	19	765	0.0e+00	471	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
638997693	348	26.71	1	314	1	318	2.0e-24	107	COG5351	Uncharacterized protein	367
638997699	404	29.53	26	399	70	466	2.0e-55	209	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
638997700	527	30.78	9	524	12	536	3.0e-104	373	COG0405	Gamma-glutamyltranspeptidase	539
638997701	274	25.74	7	273	3	256	6.0e-06	45	COG0730	Uncharacterized membrane protein YfcA	258
638997702	379	34.66	1	377	24	382	3.0e-95	342	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
638997703	416	23.11	23	415	14	409	3.0e-36	146	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
638997704	837	39.76	580	833	1	252	1.0e-64	242	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
638997706	477	41.3	1	469	13	483	4.0e-128	452	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
638997707	783	57.44	15	771	18	776	0.0e+00	997	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
638997708	296	34.07	14	273	3	268	2.0e-42	166	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
638997709	452	36.16	5	439	4	427	8.0e-98	351	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
638997710	171	28.74	1	166	6	171	1.0e-14	73	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
638997711	111	47.37	6	111	11	124	2.0e-30	123	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
638997712	397	41.03	1	395	1	402	3.0e-105	375	COG3748	Uncharacterized membrane protein	407
638997715	149	22.68	8	97	3	94	7.0e-10	56.8	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
638997720	105	25.71	5	103	8	110	3.0e-06	43.9	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
638997721	764	35.61	1	742	4	709	0.0e+00	552	COG0643	Chemotaxis protein histidine kinase CheA	716
638997722	644	34.61	258	609	20	408	2.0e-36	147	COG0840	Methyl-accepting chemotaxis protein	408
638997723	190	34.46	19	166	19	162	2.0e-30	125	COG0835	Chemotaxis signal transduction protein	165
638997724	276	34.69	15	275	1	266	9.0e-60	224	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
638997725	203	40.76	6	160	2	152	1.0e-33	136	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
638997726	356	44.51	1	354	1	342	3.0e-92	332	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
638997730	421	28.61	14	421	8	382	7.0e-36	145	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
638997731	347	28.99	1	332	3	346	8.0e-49	187	COG1253	Hemolysin or related protein, contains CBS domains	429
638997732	271	27.24	3	269	4	264	4.0e-40	158	COG0300	Short-chain dehydrogenase	265
638997733	185	22.38	1	143	3	145	1.0e-08	53.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638997735	223	24.17	15	210	29	239	1.0e-15	76.9	COG3751	Proline 4-hydroxylase (includes Rps23 Pro-64 3,4-dihydroxylase Tpa1), contains SM-20 domain	252
638997736	333	32.38	5	309	14	325	1.0e-50	194	COG3608	Predicted deacylase	331
638997737	334	28	236	334	17	116	6.0e-11	61.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638997739	679	35.31	332	679	19	362	2.0e-66	247	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)	364
638997742	340	28.65	10	332	1	321	2.0e-47	182	COG0523	GTPase, G3E family	323
638997743	517	32.94	79	499	63	484	7.0e-85	308	COG0069	Glutamate synthase domain 2	485
638997745	135	35.61	3	133	6	133	2.0e-18	84.7	COG3791	Uncharacterized conserved protein	133
638997747	384	69.33	1	384	1	388	0.0e+00	664	COG0192	S-adenosylmethionine synthetase	388
638997748	460	52.21	3	452	1	420	0.0e+00	576	COG0499	S-adenosylhomocysteine hydrolase	420
638997749	277	41.58	2	276	12	287	1.0e-67	249	COG0685	5,10-methylenetetrahydrofolate reductase	291
638997750	315	31.02	3	315	2	344	3.0e-72	265	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
638997752	245	36.14	1	242	1	246	1.0e-56	212	COG1385	16S rRNA U1498 N3-methylase RsmE	246
638997753	387	26.02	1	387	1	389	1.0e-18	88	COG0475	Kef-type K+ transport system, membrane component KefB	397
638997756	402	22.72	16	394	13	407	2.0e-21	96.8	COG0738	Fucose permease	422
638997758	227	23.61	1	212	1	201	2.0e-20	93	COG0625	Glutathione S-transferase	211
638997761	1013	40.16	36	909	10	808	0.0e+00	577	COG3250	Beta-galactosidase/beta-glucuronidase	808
638997762	723	36.46	545	722	1	180	1.0e-35	144	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638997763	145	54.86	1	144	1	144	5.0e-51	193	COG1490	D-Tyr-tRNAtyr deacylase	145
638997764	322	22.97	18	296	6	264	5.0e-15	75.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638997765	1072	38.34	868	1060	5	180	2.0e-36	148	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638997766	219	30.2	19	217	6	206	2.0e-32	132	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
638997767	308	49.31	10	297	12	299	5.0e-79	288	COG0109	Polyprenyltransferase (heme O synthase)	304
638997768	337	27.38	1	331	14	315	7.0e-40	158	COG1612	Heme A synthase	323
638997770	231	22.57	2	214	23	242	4.0e-15	75.4	COG3346	Cytochrome oxidase assembly protein ShyY1	252
638997772	302	32.76	71	302	10	206	5.0e-40	158	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
638997773	187	38.89	3	177	2	179	2.0e-40	158	COG3175	Cytochrome c oxidase assembly protein Cox11	195
638997774	528	53.5	19	527	5	517	0.0e+00	545	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
638997775	379	32.18	11	268	3	232	6.0e-52	198	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
638997776	442	27.74	1	441	3	445	1.0e-51	197	COG0534	Na+-driven multidrug efflux pump	455
638997778	363	48.39	1	363	2	373	3.0e-118	418	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
638997779	168	61.39	10	167	5	160	2.0e-59	221	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
638997780	78	38.46	2	78	4	65	2.0e-09	53.9	COG3529	Predicted nucleic-acid-binding protein, contains Zn-ribbon domain	66
638997782	207	48.74	2	199	1	198	2.0e-61	228	COG0218	GTP-binding protein EngB required for normal cell division	200
638997783	210	43.8	1	120	1	121	3.0e-25	108	COG2863	Cytochrome c553	121
638997784	209	18.86	16	182	53	226	9.0e-07	47.1	COG1651	Protein-disulfide isomerase	244
638997785	273	28.63	51	271	11	258	2.0e-26	112	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
638997786	476	44.79	311	471	17	178	2.0e-39	157	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638997787	767	34.71	642	762	4	119	2.0e-21	98.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
638997787	767	34.88	333	624	41	330	9.0e-46	179	COG0642	Signal transduction histidine kinase	336
638997790	162	43.64	1	159	1	165	1.0e-50	192	COG0678	Peroxiredoxin	165
638997791	110	36.96	4	92	8	99	2.0e-14	71.1	COG3695	Alkylated DNA nucleotide flippase Atl1, participates in nucleotide excision repair, Ada-like DNA-binding domain	103
638997792	167	37.95	2	167	1	165	2.0e-36	145	COG1247	L-amino acid N-acyltransferase YncA	169
638997793	804	65.65	1	556	2	556	0.0e+00	897	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
638997794	364	34.15	1	355	1	361	5.0e-82	298	COG1195	Recombinational DNA repair ATPase RecF	363
638997795	369	41.73	2	369	1	364	5.0e-89	321	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
638997796	495	61.98	158	491	78	408	3.0e-127	449	COG0593	Chromosomal replication initiation ATPase DnaA	408
638997797	57	79.55	14	57	1	44	2.0e-06	43.7	COG0230	Ribosomal protein L34	44
638997798	120	35.96	7	120	1	114	5.0e-16	76.5	COG0594	RNase P protein component	117
638997799	559	47.54	263	558	5	307	2.0e-81	296	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
638997800	455	50.98	3	455	2	454	0.0e+00	552	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
638997801	140	27.87	8	126	8	127	3.0e-10	57.7	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
638997803	302	29.14	1	295	7	289	2.0e-42	166	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
638997804	206	49.74	8	197	6	191	2.0e-54	205	COG0807	GTP cyclohydrolase II	193
638997805	326	32.93	1	324	1	330	6.0e-52	198	COG3380	Predicted NAD/FAD-dependent oxidoreductase	331
638997808	217	38.81	1	217	3	220	5.0e-55	207	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
638997809	206	44.39	1	205	3	204	9.0e-53	199	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
638997810	129	50.46	21	129	2	103	2.0e-24	104	COG0023	Translation initiation factor 1 (eIF-1/SUI1)	104
638997811	100	57.14	1	98	6	103	1.0e-32	130	COG3492	Uncharacterized protein	104
638997815	221	30.58	17	221	3	206	2.0e-22	99.6	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
638997816	160	40.91	1	153	5	148	3.0e-25	108	COG1963	Acid phosphatase family membrane protein YuiD	153
638997819	224	40.96	31	218	1	187	5.0e-37	147	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
638997820	169	42.21	7	160	2	154	8.0e-28	116	COG1522	DNA-binding transcriptional regulator, Lrp family	154
638997821	109	35.11	13	106	3	88	8.0e-08	49	COG0776	Bacterial nucleoid DNA-binding protein	94
638997822	418	36.88	102	364	85	344	8.0e-53	201	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
638997823	775	58.21	1	775	7	780	0.0e+00	970	COG2183	Transcriptional accessory protein Tex/SPT6	780
638997825	208	30.35	11	204	1	201	5.0e-32	131	COG0406	Broad specificity phosphatase PhoE	208
638997828	333	30.55	27	333	3	303	3.0e-30	126	COG1575	1,4-dihydroxy-2-naphthoate octaprenyltransferase	303
638997829	336	63.14	1	331	1	330	0.0e+00	469	COG1494	Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase or related protein	332
638997830	266	39.69	14	266	2	256	1.0e-70	259	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
638997832	190	35.98	15	173	8	169	4.0e-32	131	COG3703	Cation transport regulator ChaC	190
638997833	212	54.98	3	212	5	214	9.0e-76	276	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
638997837	819	20.47	12	807	2	724	3.0e-61	230	COG1033	Predicted exporter protein, RND superfamily	727
638997838	201	20	1	195	2	195	2.0e-08	53.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638997840	280	39.16	1	276	2	286	5.0e-64	237	COG2996	Predicted RNA-binding protein, contains S1 domains,  virulence factor B family	287
638997843	240	22.36	6	218	7	230	7.0e-13	67.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638997846	518	39.81	12	514	1	509	2.0e-122	433	COG0578	Glycerol-3-phosphate dehydrogenase	532
638997847	107	33.85	39	103	2	66	3.0e-06	43.7	COG2841	Uncharacterized conserved protein YdcH, DUF465 family	72
638997848	285	26.57	5	282	15	299	1.0e-32	133	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
638997850	800	48.17	7	797	4	740	0.0e+00	691	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
638997853	299	29.24	4	299	3	293	4.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
638997854	344	47.72	19	344	12	338	1.0e-95	343	COG2130	NADPH-dependent curcumin reductase CurA	340
638997855	202	31.07	1	200	1	206	9.0e-23	100	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
638997856	129	31.09	3	119	4	119	2.0e-11	61.2	COG4994	Uncharacterized protein	120
638997858	268	25.4	11	124	23	148	6.0e-06	45	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
638997862	309	18.75	1	308	14	327	5.0e-19	88.5	COG0618	nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs	332
638997864	288	57.25	18	279	3	262	3.0e-88	318	COG3739	Uncharacterized membrane protein YoaT, DUF817 family	263
638997866	295	44.75	111	290	2	181	1.0e-42	166	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638997869	202	32.05	23	174	21	176	5.0e-18	84.5	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
638997870	430	32.14	66	386	9	344	2.0e-55	210	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
638997871	261	40.91	1	261	1	262	5.0e-61	227	COG3483	Tryptophan 2,3-dioxygenase (vermilion)	262
638997872	390	19.74	29	390	31	403	5.0e-19	89.2	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
638997873	307	60.07	1	303	7	308	8.0e-113	400	COG2313	Pseudouridine-5'-phosphate glycosidase (pseudoU degradation)	310
638997874	372	28.85	60	360	2	309	2.0e-29	123	COG0524	Sugar or nucleoside kinase, ribokinase family	311
638997875	705	29.04	388	702	13	343	1.0e-30	128	COG0709	Selenophosphate synthase	346
638997875	705	29.08	11	379	6	395	2.0e-59	224	COG1252	NADH dehydrogenase, FAD-containing subunit	405
638997877	362	42.65	8	340	7	333	4.0e-61	228	COG2603	tRNA 2-selenouridine synthase SelU, contains rhodanese domain	334
638997879	159	53.75	1	159	2	161	5.0e-43	166	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
638997880	370	29.79	41	323	24	310	4.0e-43	168	COG2008	Threonine aldolase	342
638997881	382	61.2	1	382	1	384	0.0e+00	561	COG1979	Alcohol dehydrogenase YqhD, Fe-dependent ADH family	384
638997885	538	28.99	131	537	6	408	3.0e-37	150	COG0840	Methyl-accepting chemotaxis protein	408
638997888	179	28.4	10	166	3	164	8.0e-20	90	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638997889	289	36.47	3	253	2	252	4.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
638997890	423	44.31	8	422	5	425	8.0e-123	434	COG0104	Adenylosuccinate synthase	430
638997894	145	26.21	1	144	1	139	4.0e-12	64.2	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
638997895	302	37.86	1	237	5	244	2.0e-34	139	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
638997896	315	36.72	11	260	1	244	8.0e-34	137	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
638997899	82	45.12	1	82	1	82	6.0e-15	72.7	COG5460	Uncharacterized conserved protein, DUF2164 family	82
638997902	204	33.95	18	177	16	177	4.0e-22	98.4	COG3038	Cytochrome b561	181
638997903	451	23.11	9	430	16	436	2.0e-32	133	COG0534	Na+-driven multidrug efflux pump	455
638997905	681	32.01	267	679	149	568	2.0e-63	237	COG4232	Thiol:disulfide interchange protein	569
638997906	102	30.61	4	97	22	117	8.0e-10	55.3	COG3462	Uncharacterized membrane protein	117
638997908	224	49.34	1	223	1	226	1.0e-63	236	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638997909	452	28.12	142	452	18	329	1.0e-31	131	COG0642	Signal transduction histidine kinase	336
638997911	250	20.19	40	240	52	244	5.0e-13	68.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
638997912	402	27.04	79	392	1	312	4.0e-43	169	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
638997913	470	37.18	393	469	3	80	5.0e-18	86.1	COG1264	Phosphotransferase system IIB components	88
638997913	470	40	1	377	3	393	3.0e-68	252	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
638997914	843	35.06	3	153	1	154	7.0e-36	146	COG2190	Phosphotransferase system IIA component	156
638997914	843	43.18	173	260	2	87	8.0e-19	89.5	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
638997914	843	45.86	287	842	1	566	0.0e+00	558	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
638997915	127	66.09	10	124	10	124	3.0e-41	160	COG3651	Uncharacterized conserved protein, DUF2237 family	125
638997916	158	41.26	1	138	7	146	9.0e-27	112	COG0071	Molecular chaperone IbpA, HSP20 family	146
638997917	192	37.06	48	190	4	145	3.0e-27	115	COG0071	Molecular chaperone IbpA, HSP20 family	146
638997918	469	44.79	30	382	9	344	3.0e-71	262	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
638997920	323	31.33	25	320	2	297	1.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
638997922	270	28.8	140	263	4	127	4.0e-16	78.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638997925	191	26.14	7	175	10	184	1.0e-19	89.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638997930	898	47.69	3	599	1	566	0.0e+00	650	COG0550	DNA topoisomerase IA	570
638997933	424	53.25	27	424	1	386	0.0e+00	495	COG0372	Citrate synthase	390
638997934	124	32	5	124	3	127	2.0e-12	64.6	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
638997935	102	30.69	2	102	16	116	3.0e-10	56.7	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
638997936	587	53.6	1	563	2	551	0.0e+00	620	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
638997937	235	56.03	1	231	3	228	2.0e-82	298	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
638997938	947	56.38	6	945	1	906	0.0e+00	1322	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
638997939	424	49.3	1	423	1	404	2.0e-113	402	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
638997940	479	50.22	1	463	1	454	0.0e+00	486	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
638997941	389	63.85	1	388	1	387	0.0e+00	545	COG0045	Succinyl-CoA synthetase, beta subunit	387
638997942	290	71.48	1	290	1	291	1.0e-125	442	COG0074	Succinyl-CoA synthetase, alpha subunit	293
638997944	438	27.5	1	428	4	429	4.0e-48	185	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
638997945	627	58.49	1	622	7	618	0.0e+00	804	COG0326	Molecular chaperone, HSP90 family	623
638997950	381	40.94	14	352	12	349	4.0e-75	275	COG2850	Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain	383
638997951	455	34.07	12	455	1	435	4.0e-108	385	COG0015	Adenylosuccinate lyase	438
638997952	210	40.1	9	209	7	207	5.0e-44	170	COG2915	Regulator of phage lambda lysogenization HflD, binds to CII and stimulates its degradation	207
638997953	364	58.29	4	363	1	356	0.0e+00	490	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
638997954	132	32.11	6	113	31	134	7.0e-12	63.1	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
638997955	392	60.97	1	392	1	391	0.0e+00	534	COG3007	Trans-2-enoyl-CoA reductase	398
638997957	743	69.72	1	743	1	743	0.0e+00	1187	COG2838	Monomeric isocitrate dehydrogenase	744
638997958	87	47.76	1	67	1	67	7.0e-20	88.7	COG1278	Cold shock protein, CspA family	67
638997959	113	58.14	22	107	21	106	6.0e-32	129	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
638997960	756	47.26	1	749	1	783	0.0e+00	852	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
638997961	72	72.22	1	72	1	72	1.0e-24	104	COG0361	Translation initiation factor IF-1	75
638997962	243	43.51	12	242	10	246	3.0e-67	248	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
638997963	241	52.48	15	216	3	203	1.0e-65	243	COG2360	Leu/Phe-tRNA-protein transferase	221
638997965	209	30.1	1	205	4	207	1.0e-30	126	COG2834	Outer membrane lipoprotein-sorting protein	211
638997966	439	55.05	1	433	1	435	0.0e+00	586	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
638997967	131	40.32	8	131	4	126	2.0e-17	81	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
638997968	429	57.77	1	427	1	426	0.0e+00	555	COG0172	Seryl-tRNA synthetase	429
638997969	456	45.45	1	206	1	209	1.0e-49	190	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
638997969	456	56.97	210	453	1	242	1.0e-91	330	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
638997970	323	26.67	6	323	3	326	1.0e-41	163	COG0547	Anthranilate phosphoribosyltransferase	338
638997971	103	36	4	103	12	111	3.0e-22	96.9	COG2920	Sulfur relay (sulfurtransferase) protein, DsrC/TusE family	111
638997973	115	21.93	5	115	5	118	2.0e-08	50.6	COG2923	Sulfur relay (sulfurtransferase) complex TusC component, DsrF/TusC family	118
638997974	128	41.41	1	127	1	126	1.0e-24	104	COG1553	Sulfur relay (sulfurtransferase) complex TusBCD TusD component, DsrE family	126
638997975	223	32.88	11	223	13	233	6.0e-24	104	COG0670	Integral membrane protein, interacts with FtsH	233
638997977	250	31.88	1	227	3	227	1.0e-29	123	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638997978	883	22.84	139	703	75	695	1.0e-20	95.6	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
638997979	976	34.7	17	972	6	972	0.0e+00	699	COG1026	Zn-dependent peptidase, M16 (insulinase) family	978
638997981	274	41.03	1	271	1	261	5.0e-74	271	COG0708	Exonuclease III	261
638997982	191	45.88	1	190	3	196	3.0e-66	244	COG1435	Thymidine kinase	201
638997985	290	36.86	5	277	4	273	4.0e-35	142	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
638997986	244	43.29	1	225	4	234	1.0e-67	249	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
638997987	169	23.6	1	157	2	162	1.0e-16	79.9	COG2716	Glycine cleavage system regulatory protein	176
638997988	549	59.4	2	530	1	531	0.0e+00	733	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
638997989	340	68.44	1	339	2	340	0.0e+00	500	COG4239	ABC-type microcin C transport system, permease component YejE	341
638997990	363	66.21	1	362	1	363	0.0e+00	543	COG4174	ABC-type microcin C transport system, permease component YejB	364
638997991	599	29.7	1	596	7	562	3.0e-83	303	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
638997992	152	32.71	15	121	13	118	7.0e-11	59.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
638997998	115	41.07	6	61	5	60	6.0e-07	46.4	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
638998003	287	39.44	3	283	2	277	1.0e-78	286	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
638998004	389	49.61	3	384	2	384	0.0e+00	467	COG1168	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	388
638998006	203	20.9	39	197	2	177	6.0e-16	77.6	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
638998007	330	28.49	1	330	2	299	3.0e-30	126	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
638998008	625	24.14	274	618	3	329	3.0e-24	107	COG0642	Signal transduction histidine kinase	336
638998009	725	34.66	470	719	1	250	3.0e-56	214	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
638998011	278	20.92	3	273	1	276	1.0e-12	67	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638998012	355	29.82	11	352	1	313	5.0e-34	138	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
638998013	359	29.1	56	351	1	289	2.0e-36	146	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
638998014	251	42.13	15	245	3	237	2.0e-64	239	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
638998015	260	44.58	7	253	2	250	7.0e-70	257	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
638998016	395	27.55	15	368	1	356	5.0e-34	139	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
638998017	500	32.75	10	498	19	530	3.0e-102	365	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
638998018	202	24.1	9	201	1	194	2.0e-11	62.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638998021	224	49.07	9	224	1	209	5.0e-56	210	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
638998022	379	26.42	73	373	47	361	2.0e-34	139	COG4585	Signal transduction histidine kinase	365
638998024	417	19.52	41	403	2	287	8.0e-09	55.2	COG4974	Site-specific recombinase XerD	300
638998025	460	37.36	1	447	1	454	1.0e-117	416	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
638998027	162	24.52	6	157	21	175	3.0e-10	58.1	COG3149	Type II secretory pathway, component PulM	181
638998028	418	18.07	1	410	7	385	3.0e-12	67	COG3297	Type II secretory pathway, component PulL	390
638998029	343	27.13	5	304	1	316	1.0e-34	140	COG3156	Type II secretory pathway, component PulK	323
638998033	138	43.45	1	134	4	148	4.0e-19	87	COG2165	Type II secretory pathway, pseudopilin PulG	149
638998034	404	40.59	1	404	1	397	2.0e-96	346	COG1459	Type II secretory pathway, component PulF	397
638998035	489	52.36	1	485	16	497	0.0e+00	565	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
638998036	719	34.65	596	719	4	126	5.0e-18	86.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
638998037	445	34.29	86	310	70	312	8.0e-35	141	COG0226	ABC-type phosphate transport system, periplasmic component	318
638998040	589	35.64	27	569	6	544	2.0e-105	377	COG0659	Sulfate permease or related transporter, MFS superfamily	554
638998041	308	50.16	1	308	1	310	2.0e-82	299	COG2025	Electron transfer flavoprotein, alpha subunit	313
638998042	250	48.85	1	249	1	260	1.0e-64	239	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
638998043	551	30.15	5	464	1	396	5.0e-72	265	COG0644	Dehydrogenase (flavoprotein)	396
638998043	551	34.69	452	548	11	96	9.0e-07	48.8	COG2440	Ferredoxin-like protein FixX	99
638998045	202	20.61	5	167	4	168	2.0e-06	46.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638998046	117	57.52	7	117	6	117	3.0e-39	153	COG3215	Tfp pilus assembly protein PilZ	117
638998047	320	28.9	7	309	6	313	1.0e-33	137	COG0470	DNA polymerase III, delta prime subunit	324
638998048	206	45.37	1	204	1	204	2.0e-59	222	COG0125	Thymidylate kinase	208
638998049	347	40.42	1	332	9	341	1.0e-94	339	COG1559	Cell division protein YceG, involved in septum cleavage	342
638998050	267	29	1	254	1	267	6.0e-37	147	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
638998051	412	56.8	3	412	2	411	0.0e+00	495	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
638998053	78	61.04	1	77	3	79	7.0e-13	65.7	COG0236	Acyl carrier protein	80
638998054	247	43.48	1	244	1	250	1.0e-47	183	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638998055	308	54.61	1	303	1	304	5.0e-94	337	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
638998056	248	36.82	7	241	97	334	1.0e-47	183	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
638998058	59	55.56	1	53	1	54	4.0e-12	63	COG0333	Ribosomal protein L32	57
638998059	171	30.29	1	171	1	174	1.0e-17	83.1	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
638998060	191	36.84	1	188	2	189	6.0e-44	170	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
638998061	327	31.72	20	316	1	306	2.0e-50	193	COG0616	Periplasmic serine protease, ClpP class	317
638998062	313	41.72	4	302	1	289	3.0e-75	275	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
638998063	868	52.35	1	487	4	487	0.0e+00	514	COG1530	Ribonuclease G or E	487
638998064	335	32.54	1	334	1	286	2.0e-63	236	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
638998065	155	42.95	1	149	3	138	2.0e-34	138	COG0394	Protein-tyrosine-phosphatase	139
638998066	220	46.15	1	220	30	247	4.0e-62	230	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
638998067	329	40.45	1	297	6	310	9.0e-62	230	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
638998068	128	32.8	2	126	15	136	4.0e-21	93.7	COG0848	Biopolymer transport protein ExbD	137
638998069	195	31.75	1	187	23	210	1.0e-28	120	COG0811	Biopolymer transport protein ExbB/TolQ	216
638998070	732	25.86	447	721	3	285	5.0e-27	116	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
638998071	227	45.45	6	224	1	220	7.0e-71	260	COG1136	ABC-type lipoprotein export system, ATPase component	226
638998072	384	42.12	1	383	30	408	2.0e-89	322	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
638998074	356	43.92	7	341	17	346	3.0e-101	362	COG2957	Agmatine/peptidylarginine deiminase	346
638998075	704	28.72	26	700	17	635	2.0e-100	360	COG1199	Rad3-related DNA helicase	654
638998076	281	62.72	2	280	1	279	5.0e-125	440	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
638998077	191	44.85	14	178	1	165	3.0e-48	185	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
638998079	610	17.65	137	387	36	288	5.0e-07	50.1	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
638998080	90	64.44	1	90	2	91	2.0e-29	120	COG0776	Bacterial nucleoid DNA-binding protein	94
638998082	666	46.94	4	665	197	814	0.0e+00	709	COG0495	Leucyl-tRNA synthetase	814
638998083	347	33.54	7	332	5	331	2.0e-50	192	COG1466	DNA polymerase III, delta subunit	334
638998085	454	28.57	7	436	12	445	4.0e-53	202	COG0534	Na+-driven multidrug efflux pump	455
638998086	290	23.24	2	276	1	282	2.0e-16	79.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
638998087	200	39.9	1	196	2	198	2.0e-31	129	COG1279	Arginine exporter protein ArgO	202
638998088	550	41.6	7	525	1	504	3.0e-100	359	COG0366	Glycosidase	505
638998090	484	48.73	10	479	2	467	0.0e+00	533	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638998091	152	40	1	136	6	142	2.0e-27	115	COG0071	Molecular chaperone IbpA, HSP20 family	146
638998092	234	17.3	9	225	3	225	3.0e-12	65.6	COG2384	tRNA A22 N-methylase	226
638998094	145	25.55	9	144	1	135	9.0e-19	86.1	COG0824	Acyl-CoA thioesterase FadM	137
638998095	614	50.14	261	613	4	342	2.0e-95	343	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
638998096	621	38.15	5	497	2	484	4.0e-116	412	COG0358	DNA primase (bacterial type)	568
638998097	149	54.05	2	148	1	148	2.0e-34	138	COG1610	Uncharacterized conserved protein YqeY	148
638998098	71	59.09	1	66	1	66	1.0e-07	48.3	COG0828	Ribosomal protein S21	67
638998099	342	55.26	1	341	1	340	5.0e-130	457	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
638998100	119	36.21	1	115	1	116	6.0e-25	106	COG1539	Dihydroneopterin aldolase	121
638998101	170	38.41	6	151	2	149	7.0e-29	119	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
638998102	204	32.85	24	203	5	211	2.0e-20	92.7	COG2755	Lysophospholipase L1 or related esterase	216
638998103	231	59.91	6	230	2	228	2.0e-75	275	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
638998104	831	34.25	5	831	1	829	0.0e+00	581	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
638998105	207	45.81	1	203	1	194	3.0e-64	238	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
638998106	105	25	1	103	5	103	4.0e-14	69.6	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
638998109	398	54.5	182	391	2	212	1.0e-58	220	COG0560	Phosphoserine phosphatase	212
638998110	694	26.38	440	693	2	254	2.0e-41	164	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
638998113	346	43.25	22	346	14	339	3.0e-92	332	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
638998114	190	46.21	1	132	1	131	9.0e-36	143	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
638998115	316	48.3	1	314	2	320	1.0e-88	319	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
638998116	186	26.14	20	166	1	152	6.0e-10	57.4	COG3109	sRNA-binding protein	208
638998118	283	28.83	11	280	2	239	2.0e-47	182	COG0688	Phosphatidylserine decarboxylase	239
638998121	420	23.28	5	231	19	243	1.0e-11	64.9	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
638998122	593	32.87	34	455	5	392	7.0e-74	272	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638998123	588	30.68	37	456	7	387	4.0e-66	246	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638998126	388	27.85	12	365	23	394	1.0e-69	257	COG0019	Diaminopimelate decarboxylase	394
638998127	399	45.71	1	392	1	380	1.0e-115	409	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
638998133	255	35.2	7	250	1	249	3.0e-16	78.9	COG0730	Uncharacterized membrane protein YfcA	258
638998134	213	17.82	8	209	2	200	5.0e-06	45	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638998135	181	21.9	50	179	13	149	3.0e-07	48.4	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
638998136	301	29.07	35	284	14	264	2.0e-27	116	COG3752	Steroid 5-alpha reductase family enzyme	272
638998137	314	25.4	8	307	1	311	4.0e-31	128	COG0524	Sugar or nucleoside kinase, ribokinase family	311
638998139	773	28.17	7	773	7	788	6.0e-118	418	COG0417	DNA polymerase elongation subunit (family B)	792
638998141	337	27.98	5	334	1	311	3.0e-40	159	COG0524	Sugar or nucleoside kinase, ribokinase family	311
638998142	791	38.75	118	732	6	606	0.0e+00	489	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
638998144	161	51.32	1	152	2	150	3.0e-46	177	COG1683	Uncharacterized conserved protein YbbK, DUF523 family	156
638998145	615	35	320	559	10	249	1.0e-33	138	COG1808	Uncharacterized membrane protein	334
638998146	468	47.25	4	468	5	443	0.0e+00	497	COG0174	Glutamine synthetase	443
638998147	544	28.57	450	540	4	93	9.0e-09	55.7	COG0607	Rhodanese-related sulfurtransferase	110
638998147	544	34.96	57	443	2	383	2.0e-91	329	COG0301	Adenylyl- and sulfurtransferase ThiI, participates in tRNA 4-thiouridine and thiamine biosynthesis	383
638998148	912	38.33	724	902	1	180	1.0e-39	158	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638998149	149	55.7	1	149	5	153	3.0e-50	190	COG1952	Preprotein translocase subunit SecB	157
638998150	86	47.5	3	80	1	80	4.0e-20	89.6	COG0695	Glutaredoxin	80
638998151	139	40.95	36	139	5	109	4.0e-18	83.8	COG0607	Rhodanese-related sulfurtransferase	110
638998152	517	57.53	5	515	4	509	0.0e+00	692	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
638998154	154	26.79	21	125	20	125	8.0e-09	53.1	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
638998155	374	28.75	5	372	22	419	1.0e-47	184	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
638998156	445	41.83	15	408	1	400	1.0e-99	356	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
638998157	259	36.64	16	245	16	247	5.0e-41	161	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
638998159	258	33.2	12	254	3	255	1.0e-51	196	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
638998162	202	23.35	14	193	13	205	2.0e-08	53	COG2755	Lysophospholipase L1 or related esterase	216
638998163	461	33.69	3	460	1	454	4.0e-95	341	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
638998164	443	27.35	4	443	2	454	6.0e-57	215	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
638998165	312	62.91	3	303	1	300	3.0e-116	411	COG0031	Cysteine synthase	300
638998166	198	40	3	182	5	189	5.0e-39	153	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
638998167	220	20.75	1	199	44	255	2.0e-18	85.7	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
638998168	552	35.57	5	430	1	415	1.0e-60	227	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
638998168	552	39.02	466	544	18	99	2.0e-11	64.2	COG0607	Rhodanese-related sulfurtransferase	110
638998169	357	48.54	15	355	1	337	7.0e-92	330	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
638998170	173	43.88	22	160	7	144	3.0e-37	148	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
638998171	447	36.59	95	381	3	230	2.0e-49	190	COG0860	N-acetylmuramoyl-L-alanine amidase	231
638998172	632	44.9	13	631	4	638	0.0e+00	660	COG0323	DNA mismatch repair ATPase MutL	638
638998173	321	46.67	5	319	2	303	4.0e-93	334	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
638998174	82	74.03	1	76	1	77	4.0e-25	106	COG1923	sRNA-binding regulator protein Hfq	77
638998175	436	51.5	7	406	1	399	4.0e-127	448	COG2262	50S ribosomal subunit-associated GTPase HflX	411
638998176	395	30.07	69	337	1	274	1.0e-44	173	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
638998177	309	27.48	10	304	8	284	2.0e-38	153	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
638998178	398	32.14	5	389	1	385	2.0e-69	256	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
638998179	430	58.84	2	429	1	430	0.0e+00	616	COG0104	Adenylosuccinate synthase	430
638998180	785	46.16	24	749	2	706	0.0e+00	693	COG0557	Exoribonuclease R	706
638998181	252	42.06	2	252	19	259	2.0e-63	235	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
638998187	321	41.99	1	321	6	328	3.0e-63	235	COG0714	MoxR-like ATPase	329
638998188	162	50.63	7	162	24	181	1.0e-37	148	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
638998189	824	45.95	10	817	1	749	0.0e+00	806	COG0058	Glucan phosphorylase	750
638998190	312	32.15	16	312	14	324	2.0e-56	213	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
638998191	137	53.28	1	136	1	137	1.0e-44	172	COG3565	Predicted dioxygenase of extradiol dioxygenase family	138
638998192	252	24.89	23	250	12	225	6.0e-22	98	COG2045	Phosphosulfolactate phosphohydrolase or related enzyme	230
638998193	497	30.23	65	232	11	181	4.0e-19	90.2	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638998193	497	39.61	243	497	1	253	3.0e-67	249	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
638998194	415	61.92	1	405	1	393	0.0e+00	583	COG1015	Phosphopentomutase	397
638998195	437	50.8	1	437	1	435	0.0e+00	521	COG0213	Thymidine phosphorylase	435
638998196	257	37.96	8	252	5	228	2.0e-54	205	COG0274	Deoxyribose-phosphate aldolase	228
638998197	135	32.59	1	134	20	151	6.0e-21	93.4	COG1406	Chemotaxis protein CheX, a CheY~P-specific phosphatase	153
638998199	339	18.37	15	333	13	336	4.0e-07	49.4	COG0642	Signal transduction histidine kinase	336
638998200	960	32.17	21	928	9	916	0.0e+00	643	COG1025	Secreted/periplasmic Zn-dependent peptidases, insulinase-like	937
638998201	286	45.1	1	286	20	304	3.0e-66	245	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
638998202	942	66.63	1	941	3	935	0.0e+00	1547	COG0178	Excinuclease UvrABC ATPase subunit	935
638998203	404	22.78	26	382	30	384	2.0e-17	83.7	COG2814	Predicted arabinose efflux permease, MFS family	394
638998204	181	37.64	4	181	1	167	1.0e-32	132	COG0629	Single-stranded DNA-binding protein	167
638998205	302	25.51	11	293	4	278	1.0e-30	127	COG1091	dTDP-4-dehydrorhamnose reductase	281
638998207	322	39.32	7	322	4	322	3.0e-76	278	COG0142	Geranylgeranyl pyrophosphate synthase	322
638998210	297	38.95	3	283	2	279	2.0e-60	225	COG0287	Prephenate dehydrogenase	279
638998211	228	54.5	4	224	2	220	8.0e-72	263	COG0283	Cytidylate kinase	222
638998212	560	59.16	1	545	1	537	0.0e+00	575	COG0539	Ribosomal protein S1	541
638998213	101	50	6	99	2	94	1.0e-29	121	COG0776	Bacterial nucleoid DNA-binding protein	94
638998215	374	23.88	12	358	35	380	6.0e-30	125	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
638998218	265	33.33	1	252	1	248	4.0e-42	165	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638998219	314	29.81	45	308	3	262	1.0e-49	190	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
638998221	364	17.07	79	356	85	362	2.0e-08	53.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638998222	342	28.69	1	340	3	341	9.0e-49	187	COG0673	Predicted dehydrogenase	342
638998223	405	21.18	1	405	10	431	3.0e-37	149	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
638998224	701	30.58	3	687	5	687	3.0e-121	429	COG3345	Alpha-galactosidase	687
638998225	283	36.59	9	282	6	281	6.0e-57	214	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
638998226	292	36.62	7	287	4	287	5.0e-52	198	COG1175	ABC-type sugar transport system, permease component	295
638998227	503	56.73	4	491	2	491	0.0e+00	730	COG0554	Glycerol kinase	499
638998228	690	28.29	286	688	9	408	5.0e-44	172	COG0840	Methyl-accepting chemotaxis protein	408
638998229	149	35.22	2	148	5	158	5.0e-38	150	COG2131	Deoxycytidylate deaminase	164
638998233	429	25.42	5	402	14	431	9.0e-42	164	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
638998234	131	41.75	13	115	10	112	2.0e-21	94.9	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
638998235	300	22.49	92	299	43	240	3.0e-18	86.2	COG1360	Flagellar motor protein MotB	244
638998237	551	34.21	4	549	16	613	5.0e-129	455	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
638998238	782	38.66	140	723	155	732	0.0e+00	510	COG1501	Alpha-glucosidase, glycosyl hydrolase family GH31	772
638998239	738	52.85	36	737	19	695	0.0e+00	820	COG1298	Flagellar biosynthesis pathway, component FlhA	696
638998240	439	23.22	1	427	1	396	5.0e-45	175	COG1419	Flagellar biosynthesis GTPase FlhF	407
638998241	274	37.92	7	271	2	262	3.0e-52	198	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
638998242	238	42.26	1	237	16	247	3.0e-52	198	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
638998244	300	33.19	75	300	2	217	5.0e-45	174	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
638998245	735	38.6	4	735	4	711	0.0e+00	630	COG0643	Chemotaxis protein histidine kinase CheA	716
638998247	342	45.19	3	342	2	344	4.0e-102	364	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
638998248	244	34.98	1	242	3	245	4.0e-51	194	COG1291	Flagellar motor component MotA	266
638998249	253	24.28	18	240	15	240	1.0e-21	97	COG1360	Flagellar motor protein MotB	244
638998250	255	38.91	1	255	2	253	3.0e-49	188	COG1192	Cellulose biosynthesis protein BcsQ	259
638998252	159	38.85	1	157	5	161	2.0e-36	145	COG0835	Chemotaxis signal transduction protein	165
638998254	237	44.34	7	225	29	248	1.0e-57	216	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
638998258	345	45.51	12	334	4	326	3.0e-106	378	COG0240	Glycerol-3-phosphate dehydrogenase	329
638998260	147	34.48	1	137	1	144	5.0e-20	90.3	COG2062	Phosphohistidine phosphatase SixA	163
638998261	274	19.79	1	274	2	280	6.0e-13	68.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638998262	313	35.86	19	306	1	279	1.0e-52	200	COG2890	Methylase of polypeptide chain release factors	280
638998263	368	56.68	2	361	1	366	0.0e+00	512	COG0082	Chorismate synthase	369
638998265	387	34.84	5	291	2	288	5.0e-65	241	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
638998267	218	37.13	10	210	1	202	2.0e-40	158	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
638998268	523	44.02	8	523	2	505	0.0e+00	555	COG3046	Uncharacterized protein related to deoxyribodipyrimidine photolyase	505
638998272	268	31.71	98	261	55	216	4.0e-27	115	COG1261	Flagella basal body P-ring formation protein FlgA	220
638998273	322	38.55	7	170	1	165	3.0e-34	139	COG0835	Chemotaxis signal transduction protein	165
638998274	274	39.33	8	274	4	266	5.0e-69	254	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
638998276	132	38.93	6	132	4	133	5.0e-25	106	COG1815	Flagellar basal body rod protein FlgB	133
638998277	146	47.26	1	146	1	137	5.0e-41	160	COG1558	Flagellar basal body rod protein FlgC	137
638998278	248	30.58	4	244	3	221	9.0e-27	113	COG1843	Flagellar hook assembly protein FlgD	222
638998280	247	45.63	1	247	1	251	6.0e-71	260	COG4787	Flagellar basal body rod protein FlgF	251
638998281	261	53.21	1	261	1	264	3.0e-80	291	COG4786	Flagellar basal body rod protein FlgG	265
638998282	229	36.68	5	224	2	229	2.0e-45	175	COG2063	Flagellar basal body L-ring protein FlgH	230
638998283	339	33.93	70	336	54	333	9.0e-43	167	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
638998285	364	53.95	1	364	3	365	1.0e-121	429	COG1706	Flagellar basal body P-ring protein FlgI	365
638998286	310	34.91	136	304	20	181	6.0e-36	144	COG1705	Flagellum-specific peptidoglycan hydrolase FlgJ	201
638998287	1025	31.79	1	449	4	443	1.0e-70	262	COG1256	Flagellar hook-associated protein FlgK	552
638998288	418	22.65	4	418	2	358	1.0e-39	157	COG1344	Flagellin and related hook-associated protein FlgL	360
638998290	321	34.39	2	306	6	309	3.0e-52	199	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638998291	388	34.85	15	381	1	355	1.0e-82	300	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
638998292	397	21.47	1	360	3	363	7.0e-43	168	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
638998293	354	39.55	2	353	11	341	7.0e-84	304	COG2089	Sialic acid synthase SpsE, contains C-terminal SAF domain	347
638998296	232	33.62	1	232	5	228	5.0e-42	164	COG1083	CMP-N-acetylneuraminic acid synthetase	228
638998297	439	28.44	1	416	6	431	5.0e-83	301	COG0001	Glutamate-1-semialdehyde aminotransferase	432
638998298	253	24.71	1	252	4	251	3.0e-28	119	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638998300	699	18.95	136	610	69	529	1.0e-24	108	COG2604	Uncharacterized conserved protein	594
638998301	747	33.46	3	271	1	272	1.0e-32	135	COG1344	Flagellin and related hook-associated protein FlgL	360
638998304	1303	34.41	1	392	3	395	3.0e-42	168	COG1345	Flagellar capping protein FliD	483
638998305	408	35.35	16	403	1	401	2.0e-77	283	COG0004	Ammonia channel protein AmtB	409
638998307	330	22.22	84	326	18	243	4.0e-14	72.6	COG1647	Esterase/lipase	243
638998308	333	51.99	1	301	2	303	1.0e-115	409	COG1054	Predicted sulfurtransferase	308
638998309	452	41.21	1	395	3	347	1.0e-105	376	COG0826	Collagenase-like protease, PrtC family	347
638998311	353	29.28	9	350	2	307	1.0e-51	197	COG2017	Galactose mutarotase or related enzyme	308
638998312	383	48.19	1	380	3	386	8.0e-117	413	COG0153	Galactokinase	390
638998313	349	49.1	11	340	1	330	6.0e-96	344	COG1085	Galactose-1-phosphate uridylyltransferase	338
638998314	333	39.64	2	333	1	332	8.0e-83	300	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
638998315	373	61.19	1	371	1	371	0.0e+00	502	COG0686	Alanine dehydrogenase	371
638998316	257	42.17	1	240	7	254	4.0e-67	248	COG0796	Glutamate racemase	269
638998317	622	38.18	32	602	4	565	0.0e+00	468	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
638998318	158	32.7	1	156	11	169	4.0e-25	107	COG2716	Glycine cleavage system regulatory protein	176
638998319	960	53.56	7	444	1	449	0.0e+00	591	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
638998319	960	60.37	453	930	11	496	0.0e+00	710	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
638998320	129	59.23	1	129	2	131	8.0e-41	159	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
638998321	363	45.65	1	361	4	376	6.0e-103	367	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
638998324	185	50	2	185	1	184	3.0e-52	197	COG2096	Cob(I)alamin adenosyltransferase	184
638998326	294	29.83	7	288	4	296	1.0e-37	150	COG1893	Ketopantoate reductase	307
638998328	95	66.32	1	95	1	95	2.0e-32	130	COG0234	Co-chaperonin GroES (HSP10)	96
638998329	548	48.64	1	534	1	524	0.0e+00	492	COG0459	Chaperonin GroEL (HSP60 family)	524
638998333	307	18.53	55	304	53	275	9.0e-07	48.1	COG3031	Type II secretory pathway, component PulC	275
638998334	653	31.29	1	605	4	552	1.0e-84	308	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
638998335	199	36.61	15	194	3	185	3.0e-38	151	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
638998338	276	42.14	1	276	2	275	1.0e-62	233	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
638998339	307	26.28	16	300	1	287	2.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
638998341	380	42.4	6	380	1	353	3.0e-106	378	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
638998342	343	57.57	2	334	5	341	1.0e-108	386	COG0709	Selenophosphate synthase	346
638998343	305	22.8	1	305	1	296	4.0e-27	115	COG0583	DNA-binding transcriptional regulator, LysR family	297
638998344	420	18.88	15	406	26	394	1.0e-06	48.3	COG2814	Predicted arabinose efflux permease, MFS family	394
638998345	344	33.33	246	341	34	127	6.0e-14	72.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638998346	487	27.14	9	487	3	414	2.0e-50	193	COG2195	Di- or tripeptidase	414
638998348	579	36.67	4	506	28	511	8.0e-114	404	COG0513	Superfamily II DNA and RNA helicase	513
638998351	290	34.12	1	283	14	307	1.0e-45	176	COG3386	Sugar lactone lactonase YvrE	307
638998352	186	24.38	1	160	1	145	3.0e-15	75	COG2236	Hypoxanthine phosphoribosyltransferase	192
638998353	297	26.35	3	295	1	292	6.0e-29	121	COG0583	DNA-binding transcriptional regulator, LysR family	297
638998356	295	27.89	8	295	1	292	3.0e-33	135	COG0583	DNA-binding transcriptional regulator, LysR family	297
638998361	323	29.43	46	304	53	309	1.0e-29	124	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
638998362	349	27.43	76	342	53	310	2.0e-24	106	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
638998364	856	19.93	15	529	24	531	1.0e-20	95.8	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
638998365	688	23.05	31	557	13	550	2.0e-49	191	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
638998366	923	39.29	12	887	1	767	0.0e+00	712	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
638998367	320	24.13	23	316	21	333	3.0e-28	119	COG3520	Predicted component of the type VI protein secretion system	335
638998368	576	28.02	1	575	2	620	1.0e-90	327	COG3519	Type VI protein secretion system component VasA	621
638998370	161	33.95	1	159	1	156	1.0e-30	126	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
638998371	505	48.06	43	504	29	491	0.0e+00	589	COG3517	Predicted component of the type VI protein secretion system	495
638998372	178	41.32	2	166	4	169	1.0e-32	133	COG3516	Predicted component of the type VI protein secretion system	169
638998375	1190	27.04	5	1188	1	1188	0.0e+00	511	COG3523	Type VI protein secretion system component VasK	1188
638998376	241	22.92	36	225	64	255	2.0e-24	105	COG3455	Type VI protein secretion system component VasF	262
638998377	445	26.59	1	442	1	444	3.0e-54	206	COG3522	Predicted component of the type VI protein secretion system	446
638998378	153	25.37	6	132	4	137	1.0e-13	69.2	COG3521	Predicted component of the type VI protein secretion system	159
638998382	267	51.55	8	265	1	254	1.0e-78	286	COG0134	Indole-3-glycerol phosphate synthase	254
638998383	343	48.97	1	341	2	338	1.0e-109	389	COG0547	Anthranilate phosphoribosyltransferase	338
638998384	204	58.03	1	193	3	191	2.0e-77	281	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
638998386	469	38.05	18	457	6	457	2.0e-107	383	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
638998387	220	43.78	1	217	2	188	2.0e-66	245	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
638998388	382	43.04	1	380	9	383	8.0e-117	413	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
638998390	420	67.15	6	419	5	412	0.0e+00	673	COG0112	Glycine/serine hydroxymethyltransferase	413
638998392	313	24.64	1	274	17	286	9.0e-10	58	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
638998394	551	47.51	3	536	1	530	0.0e+00	567	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
638998395	653	34.55	226	385	17	181	7.0e-26	112	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638998395	653	42.75	396	649	1	253	2.0e-62	234	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
638998399	236	36.21	3	234	1	240	9.0e-48	183	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
638998400	335	29.87	25	331	28	319	3.0e-37	149	COG2038	NaMN:DMB phosphoribosyltransferase	347
638998401	465	34.07	69	464	82	484	1.0e-86	313	COG0260	Leucyl aminopeptidase	485
638998402	327	39.2	26	320	8	308	2.0e-69	255	COG1560	Lauroyl/myristoyl acyltransferase	308
638998404	127	48.03	1	126	2	128	8.0e-33	132	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
638998405	635	51.5	1	629	22	651	0.0e+00	790	COG1166	Arginine decarboxylase (spermidine biosynthesis)	652
638998407	296	22.97	24	244	3	164	4.0e-14	72.2	COG0563	Adenylate kinase or related kinase	178
638998409	95	58.24	5	95	1	91	6.0e-23	99.1	COG0776	Bacterial nucleoid DNA-binding protein	94
638998410	184	33.75	30	176	14	172	1.0e-19	90	COG3161	4-hydroxybenzoate synthetase (chorismate-pyruvate lyase)	174
638998411	287	44.57	9	283	13	288	5.0e-48	184	COG0382	4-hydroxybenzoate polyprenyltransferase	289
638998412	240	45.61	11	233	3	228	3.0e-63	235	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638998413	442	32.23	75	424	92	447	2.0e-47	183	COG5002	Signal transduction histidine kinase	459
638998421	179	27.12	9	178	1	176	4.0e-21	94.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
638998422	159	37.84	10	157	2	137	6.0e-28	117	COG4315	Predicted lipoprotein with conserved Yx(FWY)xxD motif (function unknown)	138
638998433	424	18.88	64	401	62	405	3.0e-11	63.3	COG0439	Biotin carboxylase	449
638998435	110	55.26	1	110	1	112	1.0e-30	125	COG2824	Uncharacterized Zn-ribbon-containing protein	112
638998442	237	39.47	3	230	2	229	4.0e-40	158	COG0704	Phosphate uptake regulator	240
638998443	270	65.49	16	270	1	253	6.0e-128	450	COG1117	ABC-type phosphate transport system, ATPase component	253
638998444	437	35.15	147	437	1	292	4.0e-66	245	COG0581	ABC-type phosphate transport system, permease component	292
638998445	462	39.87	150	461	5	310	2.0e-65	243	COG0573	ABC-type phosphate transport system, permease component	310
638998446	336	23.48	2	320	28	317	2.0e-34	139	COG0226	ABC-type phosphate transport system, periplasmic component	318
638998447	139	39.69	4	134	3	133	1.0e-32	132	COG1607	Acyl-CoA hydrolase	157
638998448	692	21.57	205	689	2	482	3.0e-41	163	COG0366	Glycosidase	505
638998449	226	32.72	10	226	6	216	1.0e-39	156	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
638998451	284	22.26	15	261	26	277	4.0e-10	59.3	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
638998452	129	68.97	1	116	1	116	3.0e-45	173	COG0203	Ribosomal protein L17	116
638998453	333	56.01	8	322	1	313	1.0e-97	350	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
638998454	206	62.02	1	206	1	205	4.0e-60	224	COG0522	Ribosomal protein S4 or related protein	205
638998455	129	68.22	1	129	1	129	2.0e-48	183	COG0100	Ribosomal protein S11	129
638998457	209	32.34	10	197	1	199	2.0e-28	119	COG0625	Glutathione S-transferase	211
638998458	133	50.65	1	133	2	155	5.0e-40	156	COG2969	Stringent starvation protein B	155
638998464	320	35.59	89	319	3	236	4.0e-42	165	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
638998465	236	27.84	6	229	3	249	2.0e-31	129	COG1521	Pantothenate kinase type III	251
638998470	398	78.64	1	398	1	394	0.0e+00	678	COG0050	Translation elongation factor EF-Tu, a GTPase	394
638998472	122	41.67	48	119	2	73	3.0e-09	54.2	COG0690	Preprotein translocase subunit SecE	73
638998473	177	55.11	1	176	1	176	6.0e-55	206	COG0250	Transcription antitermination factor NusG	178
638998474	144	71.83	2	143	1	141	1.0e-54	205	COG0080	Ribosomal protein L11	141
638998475	231	57.89	1	227	1	228	2.0e-76	279	COG0081	Ribosomal protein L1	228
638998476	164	43.56	1	159	1	162	2.0e-31	128	COG0244	Ribosomal protein L10	175
638998477	122	69.35	1	122	1	124	2.0e-23	101	COG0222	Ribosomal protein L7/L12	124
638998479	1398	50.7	19	853	6	808	0.0e+00	888	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
638998480	124	73.98	1	123	7	129	1.0e-46	178	COG0048	Ribosomal protein S12	129
638998481	156	62.16	2	149	1	148	6.0e-54	203	COG0049	Ribosomal protein S7	148
638998482	698	65.19	1	697	1	690	0.0e+00	986	COG0480	Translation elongation factor EF-G, a GTPase	697
638998485	432	34.03	1	427	3	405	3.0e-80	292	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
638998486	178	43.92	1	178	3	191	2.0e-37	148	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
638998488	222	26.29	5	211	2	207	4.0e-35	141	COG2102	Diphthamide synthase (EF-2-diphthine--ammonia ligase)	223
638998490	299	26.44	3	292	2	292	1.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
638998491	329	33.64	3	320	1	311	8.0e-50	191	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
638998492	314	33.02	1	308	1	315	2.0e-55	209	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
638998493	331	41.64	1	324	1	313	5.0e-77	281	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
638998494	436	22.6	27	400	1	373	2.0e-29	123	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
638998495	1037	24.33	11	1011	4	1007	0.0e+00	499	COG0841	Multidrug efflux pump subunit AcrB	1009
638998499	287	30.8	6	287	20	296	8.0e-38	150	COG0501	Zn-dependent protease with chaperone function	302
638998500	722	51.5	89	715	9	627	0.0e+00	740	COG0296	1,4-alpha-glucan branching enzyme	628
638998501	707	45.82	1	704	2	692	0.0e+00	692	COG1523	Pullulanase/glycogen debranching enzyme	697
638998505	359	33	248	346	25	124	5.0e-15	75.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638998507	389	16.67	162	377	65	280	1.0e-05	44.5	COG0842	ABC-type multidrug transport system, permease component	286
638998508	328	27.17	1	274	10	279	1.0e-24	107	COG1566	Multidrug resistance efflux pump	352
638998509	437	23.74	19	428	39	443	8.0e-28	118	COG1538	Outer membrane protein TolC	457
638998510	166	34.46	1	138	4	151	2.0e-17	82.3	COG3981	Predicted acetyltransferase	174
638998514	107	50	1	102	1	102	1.0e-32	131	COG4551	Predicted protein tyrosine phosphatase	109
638998515	470	47.9	4	451	3	453	0.0e+00	468	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
638998516	172	29.45	1	151	2	164	3.0e-27	114	COG0602	Organic radical activating enzyme	212
638998517	709	39.94	1	706	1	699	0.0e+00	768	COG1328	Anaerobic ribonucleoside-triphosphate reductase	700
638998518	638	21.04	168	634	161	600	4.0e-31	130	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
638998519	319	32.52	34	315	32	311	1.0e-39	156	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
638998520	508	52.29	30	507	10	487	0.0e+00	579	COG2160	L-arabinose isomerase	497
638998521	287	35.9	171	287	7	123	4.0e-24	105	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638998522	547	34.41	1	547	1	534	3.0e-126	445	COG1069	Ribulose kinase	544
638998523	231	40	1	230	3	219	7.0e-60	224	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
638998524	325	34.39	15	324	1	239	3.0e-54	205	COG0176	Transaldolase	239
638998526	350	31.49	9	348	3	306	1.0e-54	207	COG2017	Galactose mutarotase or related enzyme	308
638998527	679	19	73	266	77	272	7.0e-06	46.5	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
638998527	679	19.81	261	667	27	424	6.0e-34	139	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
638998532	295	32.33	1	295	26	320	4.0e-39	155	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
638998533	506	46.8	8	505	1	498	0.0e+00	575	COG1129	ABC-type sugar transport system, ATPase component	500
638998534	337	39.56	4	318	1	307	1.0e-39	157	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
638998535	323	33.01	8	318	10	316	7.0e-38	151	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
638998537	252	36.04	4	114	1	111	1.0e-20	93.7	COG0789	DNA-binding transcriptional regulator, MerR family	124
638998538	444	29.17	245	380	4	164	2.0e-09	57.3	COG3179	Predicted chitinase	206
638998549	293	38.62	5	292	4	293	3.0e-53	202	COG1175	ABC-type sugar transport system, permease component	295
638998550	299	38.63	26	298	6	281	2.0e-56	212	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
638998551	437	21.11	1	434	1	430	1.0e-33	137	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
638998552	331	35.03	1	324	3	330	5.0e-59	221	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
638998553	323	58.2	6	316	4	313	2.0e-116	412	COG3940	Beta-xylosidase, GH43 family	324
638998554	352	48.44	1	352	1	338	6.0e-115	407	COG4213	ABC-type xylose transport system, periplasmic component	341
638998555	516	52.57	1	504	5	498	0.0e+00	621	COG1129	ABC-type sugar transport system, ATPase component	500
638998556	402	53.52	24	401	20	394	1.0e-115	409	COG4214	ABC-type xylose transport system, permease component	394
638998557	267	42.86	4	267	14	278	2.0e-82	299	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
638998558	255	28.46	1	255	1	252	2.0e-41	162	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
638998559	162	25.64	1	156	1	152	2.0e-15	75	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
638998560	462	65.81	3	462	1	467	0.0e+00	597	COG2213	Phosphotransferase system, mannitol-specific IIBC component	472
638998561	880	40.7	203	288	4	88	1.0e-15	79.5	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
638998561	880	42.14	48	187	1	139	2.0e-30	128	COG4668	Mannitol/fructose-specific phosphotransferase system, IIA domain	142
638998561	880	42.43	314	876	3	569	0.0e+00	547	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
638998562	390	33.56	2	382	17	455	8.0e-82	297	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
638998563	121	36.89	5	118	6	127	2.0e-20	91.1	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
638998564	346	32.85	1	344	1	325	6.0e-58	218	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
638998566	209	33.63	46	158	1	113	4.0e-12	65	COG1846	DNA-binding transcriptional regulator, MarR family	126
638998568	441	35.7	1	414	19	446	6.0e-115	408	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
638998571	555	31.47	9	550	27	562	2.0e-90	326	COG4232	Thiol:disulfide interchange protein	569
638998572	294	31.88	1	268	28	301	2.0e-48	186	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
638998578	262	20.41	24	253	34	278	1.0e-11	63.4	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
638998579	114	36.52	1	114	1	115	1.0e-26	111	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
638998580	203	28.29	1	194	3	205	5.0e-26	111	COG0655	Multimeric flavodoxin WrbA	207
638998582	324	32.81	3	319	13	325	1.0e-55	210	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
638998583	612	25.87	144	525	32	408	2.0e-44	174	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
638998585	391	37.61	10	352	18	354	2.0e-47	183	COG0628	Predicted PurR-regulated permease PerM	355
638998586	351	22.36	3	312	20	306	5.0e-17	82.4	COG3249	Uncharacterized protein	343
638998587	349	61.34	6	346	1	344	0.0e+00	494	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
638998588	216	53.5	3	202	1	200	3.0e-75	274	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
638998590	331	47.6	1	327	1	321	3.0e-94	338	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
638998591	217	34.15	1	199	1	194	2.0e-48	185	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
638998592	723	45.38	253	723	104	545	0.0e+00	479	COG2225	Malate synthase	545
638998593	280	19.71	1	278	32	297	9.0e-19	87.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
638998594	536	24.63	7	535	1	433	6.0e-108	385	COG2224	Isocitrate lyase	433
638998598	352	40.8	12	351	8	351	4.0e-97	348	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
638998599	522	31.24	5	522	30	535	1.0e-76	281	COG1178	ABC-type Fe3+ transport system, permease component	540
638998603	147	56.2	2	138	3	139	3.0e-46	177	COG1803	Methylglyoxal synthase	142
638998605	746	32.99	488	682	45	227	1.0e-30	128	COG2114	Adenylate cyclase, class 3	227
638998606	140	25.71	7	129	1	138	2.0e-08	51.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
638998607	370	25	33	236	2	181	2.0e-06	47.2	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
638998608	394	15.08	22	377	28	380	2.0e-07	50.2	COG2814	Predicted arabinose efflux permease, MFS family	394
638998609	338	23.15	39	337	1	298	9.0e-33	134	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
638998610	324	32.93	23	270	18	239	2.0e-19	89.8	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
638998614	224	35.94	4	194	2	192	9.0e-38	150	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
638998615	233	54.98	1	231	1	230	1.0e-76	279	COG1794	Aspartate/glutamate racemase	230
638998616	434	23.45	7	426	9	375	3.0e-31	129	COG0006	Xaa-Pro aminopeptidase	384
638998618	478	29.01	33	452	25	405	2.0e-60	227	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
638998619	153	41.61	6	153	7	154	2.0e-30	124	COG1522	DNA-binding transcriptional regulator, Lrp family	154
638998621	192	45.93	1	169	1	170	3.0e-41	161	COG4635	Protoporphyrinogen IX oxidase, menaquinone-dependent (flavodoxin domain)	175
638998622	707	37.03	1	665	1	653	0.0e+00	561	COG0370	Fe2+ transport system protein B	653
638998623	76	41.1	1	73	1	72	1.0e-10	58.3	COG1918	Fe2+ transport system protein FeoA	75
638998625	106	53.19	4	97	8	101	1.0e-27	114	COG3323	Uncharacterized protein	109
638998628	428	42.86	246	426	1	181	9.0e-42	164	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638998629	398	33.33	3	369	1	372	4.0e-57	215	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
638998630	324	31.53	1	317	3	333	8.0e-53	201	COG0673	Predicted dehydrogenase	342
638998634	624	27.6	174	516	13	376	4.0e-34	140	COG0366	Glycosidase	505
638998635	345	27.67	4	345	1	327	3.0e-50	192	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
638998638	502	34.75	1	484	3	566	2.0e-108	386	COG1966	Carbon starvation protein CstA	575
638998639	239	43.44	1	238	2	243	5.0e-45	174	COG3279	DNA-binding response regulator, LytR/AlgR family	244
638998640	564	48.38	7	559	4	549	0.0e+00	577	COG3275	Sensor histidine kinase, LytS/YehU family	557
638998644	224	32.53	3	85	13	95	5.0e-07	48.3	COG0640	DNA-binding transcriptional regulator, ArsR family	110
638998645	387	19.01	6	386	7	388	2.0e-12	67.2	COG2814	Predicted arabinose efflux permease, MFS family	394
638998648	270	33.73	22	270	1	230	1.0e-19	90	COG2801	Transposase InsO and inactivated derivatives	232
638998651	531	21.43	257	487	14	223	4.0e-13	70	COG3596	Predicted GTPase	296
638998654	332	23.66	1	311	6	311	8.0e-31	128	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
638998655	319	35.77	58	315	1	258	1.0e-43	170	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
638998656	293	35.66	47	290	26	255	2.0e-39	156	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
638998657	274	46.64	20	272	3	246	3.0e-83	301	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
638998658	481	33.11	11	450	9	430	4.0e-97	348	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
638998659	422	23.53	9	409	3	409	1.0e-44	174	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
638998660	214	22.55	7	208	1	196	3.0e-13	68.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638998661	489	31.71	60	485	6	451	5.0e-89	321	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
638998662	424	35.71	3	323	1	310	4.0e-82	299	COG0167	Dihydroorotate dehydrogenase	310
638998663	440	41.28	14	439	14	444	5.0e-126	444	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
638998664	501	38.67	9	487	1	470	2.0e-123	436	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638998665	883	17.31	1	841	1	866	1.0e-14	76.2	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
638998666	373	18.23	4	370	3	390	3.0e-18	86.4	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
638998668	283	22.79	4	283	2	293	2.0e-24	106	COG0583	DNA-binding transcriptional regulator, LysR family	297
638998669	234	33.33	1	215	1	202	3.0e-36	145	COG1182	FMN-dependent NADH-azoreductase	202
638998670	161	36.07	6	125	7	125	9.0e-21	93.1	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
638998677	256	26.92	29	255	2	234	3.0e-26	112	COG0412	Dienelactone hydrolase	236
638998679	888	31.1	415	756	2	335	7.0e-42	166	COG0642	Signal transduction histidine kinase	336
638998682	302	44.25	2	286	7	293	3.0e-59	222	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
638998684	557	32.5	3	557	2	552	3.0e-106	379	COG0659	Sulfate permease or related transporter, MFS superfamily	554
638998685	286	60.95	13	286	1	273	4.0e-87	314	COG0206	Cell division GTPase FtsZ	338
638998686	410	53.61	5	410	3	418	0.0e+00	468	COG0849	Cell division ATPase FtsA	418
638998687	260	24.23	4	257	11	266	7.0e-29	120	COG1589	Cell division septal protein FtsQ	269
638998688	480	51.29	12	472	1	456	0.0e+00	576	COG0773	UDP-N-acetylmuramate-alanine ligase	459
638998689	357	40.11	1	353	1	357	3.0e-88	318	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
638998690	392	40.55	25	385	15	372	2.0e-77	283	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
638998691	463	41.1	20	463	1	447	6.0e-112	398	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
638998692	360	45.24	20	360	1	316	9.0e-57	214	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
638998693	447	42.19	6	446	4	451	2.0e-109	389	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
638998694	484	45.2	14	476	4	470	0.0e+00	468	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
638998695	556	34.79	1	547	10	599	1.0e-122	434	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
638998696	91	34.88	5	90	18	103	6.0e-13	65.7	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
638998697	315	56.77	9	313	5	312	9.0e-108	383	COG0275	16S rRNA C1402 N4-methylase RsmH	314
638998698	158	49.28	8	145	1	136	3.0e-39	154	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
638998700	267	45.25	1	263	17	275	3.0e-77	282	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
638998701	607	29.89	3	596	6	602	1.0e-87	317	COG3107	Outer membrane lipoprotein LpoA, binds and activates PBP1a	604
638998702	118	49.07	9	116	5	112	8.0e-30	122	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
638998703	197	36.52	4	181	2	176	9.0e-30	123	COG0279	Phosphoheptose isomerase	176
638998704	192	28.95	4	191	6	195	2.0e-24	105	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
638998705	295	31.67	182	295	32	151	7.0e-11	61.5	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
638998706	437	43.95	9	434	1	424	7.0e-130	457	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
638998707	175	54.86	1	175	1	171	2.0e-53	202	COG0221	Inorganic pyrophosphatase	171
638998708	346	31.79	28	344	37	357	3.0e-65	242	COG5345	Uncharacterized protein	358
638998709	146	58.33	3	146	2	144	2.0e-55	208	COG0757	3-dehydroquinate dehydratase	146
638998710	156	42.38	6	156	1	139	3.0e-27	114	COG0511	Biotin carboxyl carrier protein	140
638998711	448	63.53	1	445	1	446	0.0e+00	620	COG0439	Biotin carboxylase	449
638998712	296	41	1	295	2	300	6.0e-73	267	COG2264	Ribosomal protein L11 methylase PrmA	300
638998715	329	47.08	1	322	1	322	6.0e-91	327	COG0042	tRNA-dihydrouridine synthase	323
638998716	99	63.51	26	99	25	98	3.0e-24	103	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
638998717	531	60.95	11	531	3	515	0.0e+00	755	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
638998718	426	58.78	1	426	1	425	0.0e+00	594	COG0151	Phosphoribosylamine-glycine ligase	428
638998719	783	28.37	281	628	3	336	4.0e-27	117	COG0642	Signal transduction histidine kinase	336
638998720	214	39.81	9	214	2	204	5.0e-52	197	COG2941	Demethoxyubiquinone hydroxylase, CLK1/Coq7/Cat5 family	204
638998721	474	49.57	1	466	1	457	0.0e+00	549	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638998722	358	42.49	11	354	12	355	3.0e-93	335	COG3852	Signal transduction histidine kinase, nitrogen specific	363
638998725	196	55.61	1	196	2	195	3.0e-78	284	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
638998726	204	46.27	1	200	11	202	5.0e-71	260	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
638998727	246	47.52	1	242	2	240	8.0e-77	280	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
638998728	252	68.11	3	252	2	255	5.0e-113	400	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
638998731	320	56.37	1	302	1	314	4.0e-107	381	COG0205	6-phosphofructokinase	347
638998732	755	61.14	7	752	3	753	0.0e+00	1005	COG1882	Pyruvate-formate lyase	755
638998733	814	44.71	563	814	4	256	2.0e-70	261	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
638998734	261	33.2	18	260	17	256	2.0e-60	225	COG1180	Pyruvate-formate lyase-activating enzyme	260
638998735	460	47.38	5	460	2	438	2.0e-106	379	COG0733	Na+-dependent transporter, SNF family	439
638998738	288	24.58	1	283	1	295	2.0e-26	113	COG0583	DNA-binding transcriptional regulator, LysR family	297
638998739	301	33.75	1	291	1	316	2.0e-62	232	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
638998740	147	38.73	2	141	21	161	4.0e-32	130	COG4067	Uncharacterized conserved protein	162
638998741	119	39.09	4	113	3	111	2.0e-21	94.3	COG3085	Uncharacterized conserved protein YifE, UPF0438 family	112
638998742	406	34.35	7	399	6	383	4.0e-60	225	COG2311	Uncharacterized membrane protein YeiB	394
638998743	517	47.81	1	516	1	516	0.0e+00	578	COG3634	Alkyl hydroperoxide reductase subunit AhpF	520
638998744	187	46.28	1	184	2	188	2.0e-63	235	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
638998745	299	25.75	2	298	1	294	9.0e-36	144	COG0583	DNA-binding transcriptional regulator, LysR family	297
638998747	178	33.15	1	177	15	194	2.0e-36	145	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
638998749	295	22.41	9	288	5	275	7.0e-20	91.5	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
638998751	286	46.53	2	284	3	285	1.0e-69	256	COG3001	Fructosamine-3-kinase	286
638998752	146	37.3	1	126	3	126	1.0e-22	98.9	COG3791	Uncharacterized conserved protein	133
638998754	362	29.01	63	346	9	293	1.0e-32	134	COG2382	Enterochelin esterase or related enzyme	299
638998755	267	31.64	3	256	17	265	4.0e-36	145	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
638998756	299	40.54	7	297	24	319	6.0e-72	264	COG4607	ABC-type enterochelin transport system, periplasmic component	320
638998757	312	50.47	1	311	4	320	2.0e-87	315	COG4606	ABC-type enterochelin transport system, permease component	321
638998758	330	42.58	21	330	7	316	7.0e-69	254	COG4605	ABC-type enterochelin transport system, permease component	316
638998759	252	60.71	1	252	1	252	1.0e-104	372	COG4604	ABC-type enterochelin transport system, ATPase component	252
638998761	171	27.27	11	160	1	150	2.0e-07	48.8	COG0645	Predicted kinase	170
638998762	141	41.96	1	140	1	143	2.0e-33	135	COG0698	Ribose 5-phosphate isomerase RpiB	151
638998763	69	58.93	1	56	1	56	6.0e-11	59.2	COG2906	Bacterioferritin-associated ferredoxin	63
638998764	280	20	25	280	10	259	7.0e-15	74.6	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
638998765	142	57.04	2	141	1	142	1.0e-40	158	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
638998769	131	32.31	1	129	3	131	2.0e-18	84.7	COG3791	Uncharacterized conserved protein	133
638998772	155	54.19	1	155	1	154	3.0e-45	173	COG2193	Bacterioferritin (cytochrome b1)	157
638998773	158	62.42	1	157	1	157	1.0e-50	192	COG2193	Bacterioferritin (cytochrome b1)	157
638998775	255	34.68	2	245	1	243	3.0e-58	218	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
638998776	342	43.41	10	339	7	331	6.0e-52	198	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
638998777	280	33.57	7	280	21	296	1.0e-40	160	COG4558	ABC-type hemin transport system, periplasmic component	300
638998780	655	23.56	13	655	4	607	2.0e-49	190	COG4206	Outer membrane cobalamin receptor protein	608
638998782	371	41.57	202	363	15	180	3.0e-35	142	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638998783	290	33.33	183	287	21	125	9.0e-21	94.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638998785	257	33.64	149	253	34	137	2.0e-11	62.8	COG3187	Heat shock protein HslJ	142
638998788	407	53.96	4	407	34	445	9.0e-124	437	COG3487	Uncharacterized iron-regulated protein	446
638998789	462	52.81	24	462	38	481	0.0e+00	524	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
638998791	348	24.02	3	345	6	361	2.0e-34	139	COG3490	Uncharacterized protein	366
638998793	592	17.94	10	539	2	495	3.0e-15	77.3	COG0366	Glycosidase	505
638998795	377	40	193	365	6	179	5.0e-40	158	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638998796	226	22.55	25	221	3	204	3.0e-14	72.3	COG0778	Nitroreductase	207
638998799	166	56.96	1	158	1	158	3.0e-59	220	COG2077	Peroxiredoxin	158
638998800	210	31.28	3	209	8	213	4.0e-26	111	COG3683	ABC-type uncharacterized transport system, periplasmic component	213
638998801	296	29.53	13	285	8	299	6.0e-35	141	COG2215	ABC-type nickel/cobalt efflux system, permease component RcnA	303
638998802	118	46.39	19	115	1	95	9.0e-28	115	COG2154	Pterin-4a-carbinolamine dehydratase	101
638998803	267	52.42	2	267	24	291	1.0e-89	322	COG3186	Phenylalanine-4-hydroxylase	291
638998804	415	34.07	48	364	37	344	5.0e-60	225	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
638998805	404	22.07	40	400	40	393	2.0e-10	60.6	COG2814	Predicted arabinose efflux permease, MFS family	394
638998809	214	47.21	18	214	2	198	1.0e-57	216	COG2109	ATP:corrinoid adenosyltransferase	198
638998811	393	46.51	2	388	5	385	2.0e-116	412	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
638998812	275	52.22	4	273	6	274	4.0e-82	297	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
638998813	306	47.16	1	293	4	302	2.0e-86	312	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
638998814	559	51.02	1	528	4	534	0.0e+00	514	COG2303	Choline dehydrogenase or related flavoprotein	542
638998815	487	46.57	6	482	1	471	0.0e+00	502	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638998816	200	23.86	1	175	4	178	9.0e-12	63.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638998817	217	34.7	1	216	2	217	1.0e-36	146	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
638998818	535	24.55	18	377	15	397	5.0e-55	209	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
638998819	263	22.44	7	236	2	249	2.0e-08	53.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
638998823	353	56.32	1	344	1	348	0.0e+00	512	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
638998824	372	58.49	3	372	1	371	0.0e+00	543	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
638998825	173	43.75	77	172	1	96	1.0e-25	109	COG1862	Preprotein translocase subunit YajC	97
638998826	613	47.35	101	613	16	506	4.0e-121	429	COG0342	Preprotein translocase subunit SecD	506
638998827	315	48.31	5	299	8	303	2.0e-80	292	COG0341	Preprotein translocase subunit SecF	305
638998828	337	42.86	1	314	3	314	2.0e-89	322	COG0180	Tryptophanyl-tRNA synthetase	314
638998829	161	28.28	1	141	5	149	6.0e-09	53.9	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
638998830	279	28.71	1	202	4	212	3.0e-40	159	COG1131	ABC-type multidrug transport system, ATPase component	293
638998832	124	40.34	4	122	6	123	5.0e-24	102	COG1725	DNA-binding transcriptional regulator YhcF, GntR family	125
638998834	201	17.56	55	184	27	155	3.0e-07	48.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
638998837	541	30.3	177	539	47	406	2.0e-39	157	COG0840	Methyl-accepting chemotaxis protein	408
638998838	69	64.62	6	69	3	67	2.0e-21	94	COG1278	Cold shock protein, CspA family	67
638998841	219	26.13	1	212	2	222	3.0e-27	115	COG1011	FMN phosphatase YigB, HAD superfamily	229
638998844	181	31.09	3	113	2	120	1.0e-08	53.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
638998845	319	30.69	10	284	8	242	2.0e-39	156	COG1360	Flagellar motor protein MotB	244
638998846	250	37.3	1	248	1	252	2.0e-57	215	COG1291	Flagellar motor component MotA	266
638998847	87	47.95	8	80	4	76	2.0e-11	60.7	COG1722	Exonuclease VII small subunit	81
638998848	293	38.98	1	291	1	286	3.0e-57	215	COG0142	Geranylgeranyl pyrophosphate synthase	322
638998852	180	41.24	1	176	1	166	2.0e-41	161	COG4283	Uncharacterized protein	170
638998854	1026	26.73	1	1007	2	1009	0.0e+00	503	COG0841	Multidrug efflux pump subunit AcrB	1009
638998856	626	59.07	13	625	1	623	0.0e+00	903	COG1154	Deoxyxylulose-5-phosphate synthase	627
638998857	227	38.16	1	226	4	222	2.0e-33	136	COG2738	Zn-dependent membrane protease YugP	226
638998860	126	44.74	6	118	2	115	9.0e-32	128	COG2315	Predicted DNA-binding protein with ?double-wing? structural motif, MmcQ/YjbR family	118
638998861	426	31.44	19	403	31	411	5.0e-74	272	COG2182	Maltose-binding periplasmic protein MalE	420
638998862	390	31.28	1	382	12	387	2.0e-39	156	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
638998863	427	37.66	6	402	2	387	2.0e-68	253	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
638998864	154	59.48	1	152	2	153	2.0e-63	234	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
638998870	519	23.64	98	513	137	558	3.0e-48	186	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
638998871	300	34.46	1	266	9	269	1.0e-40	160	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
638998874	593	44.25	71	569	2	497	0.0e+00	496	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
638998875	410	35.61	1	410	1	397	2.0e-85	309	COG1459	Type II secretory pathway, component PulF	397
638998885	332	28.66	19	318	7	284	2.0e-33	136	COG4974	Site-specific recombinase XerD	300
638998886	311	26.33	4	296	2	297	7.0e-30	124	COG0583	DNA-binding transcriptional regulator, LysR family	297
638998887	517	44.29	31	308	2	263	5.0e-65	242	COG2116	Formate/nitrite transporter FocA, FNT family	265
638998888	321	33.44	3	301	10	293	6.0e-45	174	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
638998889	494	30.11	40	493	16	452	4.0e-52	199	COG0534	Na+-driven multidrug efflux pump	455
638998890	335	33	130	331	80	282	4.0e-16	79.2	COG0842	ABC-type multidrug transport system, permease component	286
638998891	292	39.06	1	287	1	292	6.0e-70	257	COG1131	ABC-type multidrug transport system, ATPase component	293
638998896	414	55.64	1	405	14	406	0.0e+00	520	COG0281	Malic enzyme	432
638998898	71	56.76	1	71	1	74	7.0e-20	88.8	COG0254	Ribosomal protein L31	75
638998899	730	44.9	14	729	6	730	0.0e+00	735	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
638998900	561	40.51	1	561	3	577	0.0e+00	527	COG0018	Arginyl-tRNA synthetase	577
638998901	213	19.9	19	213	60	261	3.0e-07	48.9	COG3087	Cell division protein FtsN	264
638998902	510	35.7	31	510	3	488	5.0e-74	272	COG0168	Trk-type K+ transport system, membrane component	499
638998903	172	71.51	1	172	4	175	2.0e-74	271	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
638998904	440	68.92	1	440	1	444	0.0e+00	679	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
638998906	125	49.58	1	119	2	120	5.0e-36	143	COG3536	Uncharacterized conserved protein, DUF971 family	120
638998907	487	57.29	1	487	1	475	0.0e+00	661	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
638998909	338	47.56	3	327	2	329	4.0e-81	295	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
638998910	169	31.1	5	164	63	224	2.0e-27	115	COG1040	Predicted amidophosphoribosyltransferases	225
638998911	350	57.36	8	331	9	332	3.0e-118	418	COG0502	Biotin synthase or related enzyme	335
638998912	384	48.45	1	384	1	388	5.0e-123	434	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
638998915	239	41.94	1	217	1	212	4.0e-57	214	COG0132	Dethiobiotin synthetase	223
638998919	376	58.56	2	375	1	366	0.0e+00	573	COG0505	Carbamoylphosphate synthase small subunit	368
638998920	1070	68.94	13	408	1	393	0.0e+00	581	COG0458	Carbamoylphosphate synthase large subunit	400
638998921	158	52.29	6	158	1	151	2.0e-40	158	COG0782	Transcription elongation factor, GreA/GreB family	151
638998922	557	23.96	66	459	8	393	1.0e-45	178	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638998923	206	37.25	4	206	9	200	2.0e-48	185	COG4430	Uncharacterized conserved protein YdeI, YjbR/CyaY-like superfamily, DUF1801 family	200
638998926	459	31.78	45	455	36	456	1.0e-31	131	COG0471	Di- and tricarboxylate transporter	461
638998927	309	29.78	37	297	18	285	1.0e-39	157	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
638998928	442	27.69	4	442	7	412	5.0e-68	252	COG0232	dGTP triphosphohydrolase	412
638998929	770	29.41	314	634	20	335	2.0e-41	164	COG0642	Signal transduction histidine kinase	336
638998930	461	55.97	1	460	1	455	0.0e+00	614	COG1066	Predicted ATP-dependent serine protease	456
638998931	342	37.5	225	327	16	119	8.0e-13	68.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638998932	799	22.6	409	761	29	308	1.0e-26	116	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
638998933	168	26.11	1	145	1	154	9.0e-15	73.2	COG0655	Multimeric flavodoxin WrbA	207
638998937	120	27.97	1	114	1	110	9.0e-15	72.3	COG5646	Uncharacterized conserved protein YdhG, YjbR/CyaY-like superfamily, DUF1801 family	126
638998943	556	20.1	151	520	1	369	5.0e-26	113	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
638998943	556	36.15	1	130	1	130	3.0e-26	113	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
638998945	380	47.18	1	369	1	341	3.0e-82	299	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
638998946	40	69.7	1	33	1	33	2.0e-07	47.7	COG4890	Predicted outer membrane lipoprotein	37
638998947	543	34.59	50	542	42	536	3.0e-83	302	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
638998948	525	28.68	7	500	20	531	2.0e-55	210	COG4987	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components	573
638998950	248	47.54	4	247	3	245	3.0e-74	271	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
638998952	294	39.58	7	291	5	292	1.0e-54	206	COG1175	ABC-type sugar transport system, permease component	295
638998953	310	37.67	21	310	6	281	1.0e-54	206	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
638998954	433	22.37	5	430	14	428	3.0e-31	129	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
638998956	289	31.19	181	289	15	123	7.0e-19	88	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638998957	708	32.44	26	694	23	687	0.0e+00	482	COG3345	Alpha-galactosidase	687
638998958	474	32.65	188	463	109	402	1.0e-27	118	COG0840	Methyl-accepting chemotaxis protein	408
638998959	404	37.71	1	401	1	392	2.0e-70	259	COG0183	Acetyl-CoA acetyltransferase	392
638998960	705	37.98	1	208	4	205	4.0e-32	133	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638998960	705	40.14	311	597	1	285	2.0e-76	280	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
638998961	382	41.47	11	381	9	389	1.0e-84	306	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638998962	338	39.7	1	322	5	338	2.0e-76	279	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
638998964	315	44.07	131	305	6	181	1.0e-42	167	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638998968	478	35.71	7	478	28	486	2.0e-90	326	COG1621	Sucrose-6-phosphate hydrolase SacC, GH32 family	486
638998969	301	28.83	15	289	22	264	1.0e-45	177	COG1718	Serine/threonine-protein kinase RIO1	268
638998970	678	33.76	291	678	26	408	2.0e-48	187	COG0840	Methyl-accepting chemotaxis protein	408
638998971	1074	34.84	630	1074	29	481	1.0e-79	291	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
638998972	233	39.09	3	233	1	243	3.0e-46	178	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
638998973	175	33.89	1	174	1	177	1.0e-30	126	COG0431	NAD(P)H-dependent FMN reductase	184
638998974	362	31.59	1	339	3	334	3.0e-51	195	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
638998975	265	41.43	1	249	2	252	9.0e-58	216	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
638998976	351	41.96	20	351	3	331	1.0e-49	190	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
638998977	360	26.61	15	333	29	319	1.0e-33	137	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
638998980	354	36.14	19	349	29	358	1.0e-92	333	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
638998981	358	40.55	24	350	36	361	3.0e-105	375	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
638998982	200	34.04	12	197	1	188	2.0e-35	142	COG3658	Cytochrome b	192
638998986	223	42.98	1	218	1	226	8.0e-49	187	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638998988	95	48.42	1	95	1	95	7.0e-22	95.3	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
638998989	345	66.47	6	343	2	341	0.0e+00	470	COG1077	Actin-like ATPase involved in cell morphogenesis	342
638998990	252	37.85	1	250	22	272	7.0e-51	194	COG1792	Cell shape-determining protein MreC	284
638998991	161	29.45	1	161	1	163	1.0e-12	66	COG2891	Cell shape-determining protein MreD	167
638998992	200	48.42	1	189	4	193	5.0e-58	217	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
638998993	486	46.89	4	483	3	480	0.0e+00	472	COG1530	Ribonuclease G or E	487
638998994	1291	20.9	10	1257	1	1256	1.0e-99	358	COG3164	Uncharacterized conserved protein YhdP, contains DUF3971 and AsmA2 domains	1271
638998995	271	32.85	3	270	1	263	6.0e-46	178	COG0388	Predicted amidohydrolase	274
638998996	248	35.56	1	225	1	238	1.0e-40	160	COG3332	Uncharacterized conserved protein, contains NRDE domain	270
638998997	121	29.75	6	121	7	125	3.0e-14	70.7	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
638998999	279	52.22	1	269	3	269	7.0e-108	383	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
638999001	644	45.75	223	644	1	403	3.0e-96	346	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
638999002	886	63.1	1	886	5	887	0.0e+00	1302	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
638999003	482	50.21	1	478	4	477	0.0e+00	536	COG0469	Pyruvate kinase	477
638999004	286	40.21	1	280	1	281	6.0e-67	247	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
638999005	332	47.11	1	328	4	319	1.0e-90	326	COG0837	Glucokinase	320
638999007	731	36.51	179	730	12	518	2.0e-119	423	COG1640	4-alpha-glucanotransferase	520
638999008	364	52.09	1	359	1	338	6.0e-126	444	COG3839	ABC-type sugar transport system, ATPase component	338
638999012	295	37.97	7	291	2	293	2.0e-69	256	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
638999013	307	37.17	1	303	1	291	3.0e-70	258	COG1131	ABC-type multidrug transport system, ATPase component	293
638999014	256	19.03	28	252	43	258	7.0e-11	61.3	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
638999015	275	54.84	5	127	10	133	3.0e-48	185	COG2904	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, N-terminal domain	137
638999016	485	31	209	433	2	215	7.0e-38	151	COG2114	Adenylate cyclase, class 3	227
638999017	197	24.14	9	192	5	207	6.0e-12	64.2	COG0778	Nitroreductase	207
638999021	215	36.62	1	213	15	224	8.0e-34	137	COG1802	DNA-binding transcriptional regulator, GntR family	230
638999022	289	58.39	2	287	5	289	2.0e-97	349	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
638999023	374	44.24	1	374	10	390	2.0e-115	408	COG0372	Citrate synthase	390
638999024	871	49.54	1	864	1	861	0.0e+00	1080	COG1048	Aconitase A	861
638999025	393	56.92	6	393	3	375	3.0e-129	455	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
638999026	203	32.32	6	200	2	193	4.0e-38	151	COG0288	Carbonic anhydrase	207
638999027	669	26.41	275	664	23	408	3.0e-40	160	COG0840	Methyl-accepting chemotaxis protein	408
638999029	331	64.86	2	331	1	332	0.0e+00	468	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
638999032	400	46	1	399	7	404	1.0e-116	413	COG0303	Molybdopterin biosynthesis enzyme	404
638999033	213	46.12	4	209	3	206	5.0e-49	187	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
638999034	562	30.02	6	560	2	574	9.0e-90	324	COG3850	Signal transduction histidine kinase, nitrate/nitrite-specific	574
638999037	110	28.24	15	99	7	91	4.0e-08	49.9	COG3062	Cytoplasmic chaperone NapD for the signal peptide of periplasmic nitrate reductase NapAB	94
638999038	831	30.9	2	831	1	764	0.0e+00	557	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
638999039	150	39.04	1	142	10	153	1.0e-37	149	COG3043	Nitrate reductase cytochrome c-type subunit	155
638999040	196	61.26	5	195	1	189	3.0e-74	271	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
638999041	160	37.27	2	160	1	161	5.0e-35	140	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
638999042	593	29.29	169	550	10	383	1.0e-56	214	COG0006	Xaa-Pro aminopeptidase	384
638999043	285	26.83	158	279	5	127	5.0e-20	91.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638999044	189	28.06	3	189	11	206	9.0e-17	79.9	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
638999045	229	30.84	13	224	8	212	2.0e-26	113	COG4912	3-methyladenine DNA glycosylase AlkD	222
638999046	220	24.83	1	218	49	313	7.0e-26	110	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
638999047	196	27.32	6	192	9	202	8.0e-37	146	COG1573	Uracil-DNA glycosylase	202
638999049	238	23.14	1	237	4	248	3.0e-22	98.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638999052	124	42.19	1	122	1	128	1.0e-32	131	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
638999054	102	41.18	1	102	3	104	7.0e-19	85.4	COG3098	Uncharacterized conserved protein YqcC, DUF446 family	109
638999055	306	32.7	1	303	2	317	6.0e-59	221	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
638999056	193	53.27	1	193	2	200	2.0e-71	261	COG0605	Superoxide dismutase	204
638999058	266	38.4	17	266	4	253	1.0e-65	243	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
638999060	109	32.93	14	95	15	94	2.0e-09	54.7	COG4859	Uncharacterized protein	105
638999062	279	39.01	1	276	9	285	2.0e-65	242	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
638999066	200	60.51	5	199	3	197	4.0e-84	304	COG0529	Adenylylsulfate kinase or related kinase	197
638999068	392	25.55	18	361	4	365	9.0e-25	108	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638999069	244	22.42	4	214	3	206	1.0e-06	47.2	COG3233	Predicted deacetylase	233
638999070	197	47.62	7	195	5	185	5.0e-51	194	COG1704	Uncharacterized conserved protein	185
638999073	216	43.18	1	216	1	177	2.0e-48	185	COG0563	Adenylate kinase or related kinase	178
638999074	113	33.01	1	103	11	113	9.0e-15	72.4	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
638999075	584	29.81	1	577	1	565	4.0e-92	332	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
638999076	593	33.45	10	580	4	562	1.0e-108	387	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
638999080	756	42.08	11	750	7	726	0.0e+00	619	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
638999081	1649	30.6	110	1645	126	1618	0.0e+00	714	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
638999082	201	38.1	1	201	1	207	7.0e-36	143	COG0655	Multimeric flavodoxin WrbA	207
638999084	569	59.86	13	569	1	554	0.0e+00	822	COG2759	Formyltetrahydrofolate synthetase	554
638999087	249	30.56	1	245	4	252	2.0e-36	146	COG0300	Short-chain dehydrogenase	265
638999088	222	21.72	1	213	1	204	2.0e-10	59.5	COG0406	Broad specificity phosphatase PhoE	208
638999089	355	32.33	13	339	2	313	5.0e-48	185	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
638999090	271	32.76	1	231	6	231	4.0e-46	178	COG0300	Short-chain dehydrogenase	265
638999091	411	30.6	1	399	1	384	2.0e-59	223	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
638999092	304	25.26	10	300	1	291	9.0e-25	107	COG0583	DNA-binding transcriptional regulator, LysR family	297
638999094	176	27.78	1	176	1	180	9.0e-22	96.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638999097	396	24.43	5	389	1	387	1.0e-52	201	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
638999098	409	20.95	16	408	3	390	2.0e-16	80.6	COG2814	Predicted arabinose efflux permease, MFS family	394
638999099	324	38.03	8	308	15	315	4.0e-72	265	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
638999100	337	21.01	1	334	3	291	1.0e-16	80.5	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
638999101	409	25.83	106	406	1	297	3.0e-28	119	COG0583	DNA-binding transcriptional regulator, LysR family	297
638999102	340	23.46	1	337	1	332	7.0e-36	144	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
638999104	428	35.54	54	428	2	375	4.0e-66	245	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
638999105	223	39.25	3	216	1	210	2.0e-48	186	COG0684	Regulator of RNase E activity RraA	210
638999106	348	47.55	4	347	5	372	2.0e-107	382	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
638999107	291	24.29	16	288	1	276	3.0e-31	128	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
638999108	298	23.42	2	217	1	214	4.0e-24	105	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
638999109	316	29.41	1	307	3	325	5.0e-41	161	COG0673	Predicted dehydrogenase	342
638999110	135	31.03	15	130	11	126	6.0e-11	59.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
638999111	639	19.86	33	446	1	382	9.0e-37	148	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
638999112	398	25.75	100	397	1	293	5.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
638999115	301	26.98	175	300	2	127	2.0e-16	80.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638999116	406	24.02	5	356	1	352	1.0e-54	207	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
638999118	162	27.95	1	160	1	154	2.0e-15	75.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
638999119	352	21.89	7	336	5	331	2.0e-27	116	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
638999120	162	35.57	9	152	7	150	2.0e-28	118	COG1720	tRNA (Thr-GGU) A37 N-methylase	156
638999121	238	24.03	5	237	25	282	2.0e-19	89.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638999123	296	29.05	4	296	2	294	6.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
638999126	315	27.18	17	313	1	294	9.0e-35	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
638999127	221	29.61	1	218	3	235	2.0e-30	125	COG0412	Dienelactone hydrolase	236
638999128	249	17.86	19	236	47	262	6.0e-10	58.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
638999130	180	30.43	1	178	3	186	1.0e-22	99.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638999131	135	31.62	3	134	1	135	2.0e-21	94.7	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
638999132	174	29.07	1	169	9	180	2.0e-25	108	COG2320	GrpB domain, predicted nucleotidyltransferase, UPF0157 family	185
638999133	111	72.32	1	111	1	112	3.0e-43	167	COG2824	Uncharacterized Zn-ribbon-containing protein	112
638999134	603	24.7	9	577	4	498	9.0e-53	201	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
638999135	840	31.91	2	801	28	793	4.0e-96	346	COG2374	Predicted extracellular nuclease	798
638999140	551	30.13	27	551	197	789	3.0e-73	269	COG2374	Predicted extracellular nuclease	798
638999143	533	27.38	12	515	24	528	1.0e-64	240	COG0659	Sulfate permease or related transporter, MFS superfamily	554
638999144	123	40.38	15	117	1	104	5.0e-25	106	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
638999145	289	25.32	1	228	9	231	2.0e-24	106	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
638999148	248	28.74	1	246	1	256	1.0e-22	100	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
638999149	254	47.7	15	253	6	238	4.0e-74	271	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
638999150	260	62.21	1	172	3	174	1.0e-69	256	COG1045	Serine acetyltransferase	194
638999152	270	30.93	9	241	1	231	7.0e-40	157	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
638999153	851	38.07	6	764	11	786	0.0e+00	472	COG2374	Predicted extracellular nuclease	798
638999154	494	35.16	1	487	8	534	3.0e-111	396	COG0659	Sulfate permease or related transporter, MFS superfamily	554
638999157	401	31	78	398	42	367	7.0e-21	95.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
638999158	1046	34.44	3	1023	2	1009	0.0e+00	796	COG0841	Multidrug efflux pump subunit AcrB	1009
638999159	150	35.77	1	136	14	150	7.0e-31	126	COG1959	DNA-binding transcriptional regulator, IscR family	150
638999160	388	49.48	2	380	1	379	0.0e+00	463	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
638999161	479	41.2	34	477	1	412	6.0e-117	414	COG0719	Fe-S cluster assembly scaffold protein SufB	412
638999162	249	60.4	1	249	3	248	3.0e-100	357	COG0396	Fe-S cluster assembly ATPase SufC	251
638999163	429	29.04	20	410	12	404	6.0e-68	251	COG0719	Fe-S cluster assembly scaffold protein SufB	412
638999164	406	51.11	1	402	1	403	0.0e+00	476	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
638999165	124	35.19	16	121	4	110	1.0e-22	98.7	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
638999166	175	45.28	71	174	6	111	4.0e-26	111	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
638999167	142	47.48	2	139	3	141	1.0e-41	161	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
638999169	141	64.44	2	136	1	135	8.0e-57	212	COG0105	Nucleoside diphosphate kinase	135
638999170	386	54.08	7	359	1	349	3.0e-127	448	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
638999171	264	28.4	8	256	4	248	2.0e-30	126	COG3063	Tfp pilus assembly protein PilF	250
638999172	372	60.94	9	368	1	361	0.0e+00	538	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
638999173	416	51.06	1	414	10	427	0.0e+00	480	COG0124	Histidyl-tRNA synthetase	429
638999174	210	34.3	2	207	4	206	3.0e-31	128	COG2976	Putative negative regulator of RcsB-dependent stress response	207
638999176	458	51.02	1	438	2	442	0.0e+00	554	COG1160	Predicted GTPases	444
638999177	451	49.09	6	443	2	436	0.0e+00	470	COG1570	Exonuclease VII, large subunit	440
638999178	489	28.7	256	478	1	170	4.0e-31	129	COG0516	IMP dehydrogenase/GMP reductase	170
638999179	525	44.88	9	206	2	198	2.0e-57	217	COG0518	GMP synthase - Glutamine amidotransferase domain	198
638999179	525	69.91	207	525	1	315	0.0e+00	551	COG0519	GMP synthase, PP-ATPase domain/subunit	315
638999180	411	20.42	1	404	4	427	1.0e-24	107	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
638999181	183	40.22	1	183	1	183	3.0e-34	138	COG2119	Putative Ca2+/H+ antiporter, TMEM165/GDT1 family	190
638999182	162	50.34	1	148	4	152	4.0e-42	163	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
638999184	504	41.07	1	483	1	479	6.0e-122	431	COG0297	Glycogen synthase	487
638999185	405	49.02	1	405	9	390	1.0e-124	439	COG0448	ADP-glucose pyrophosphorylase	393
638999190	219	20.24	2	169	12	178	4.0e-09	55	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638999191	399	24.05	10	347	10	292	6.0e-19	89	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
638999195	672	24.93	3	354	1	345	7.0e-32	132	COG3320	Thioester reductase domain of alpha aminoadipate reductase Lys2 and NRPSs	382
638999195	672	35.17	380	605	2	232	1.0e-37	152	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
638999197	439	19.47	78	433	85	439	7.0e-10	58.8	COG4908	Uncharacterized protein, contains a NRPS condensation (elongation) domain	439
638999198	176	30.22	29	160	1	138	1.0e-17	82.8	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
638999199	204	21.95	24	137	7	125	8.0e-07	47.3	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
638999202	210	55.5	1	209	1	209	3.0e-86	311	COG0177	Endonuclease III	211
638999203	235	57.62	1	210	1	210	2.0e-74	272	COG4660	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfE subunit	212
638999204	228	39.8	14	214	3	194	9.0e-43	167	COG4659	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit	195
638999205	343	52.38	5	334	6	338	4.0e-86	311	COG4658	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfD subunit	338
638999206	601	51.92	11	532	1	508	0.0e+00	545	COG4656	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfC subunit	529
638999207	196	62.57	1	169	4	174	5.0e-58	217	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
638999208	193	73.82	1	191	1	191	5.0e-63	233	COG4657	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfA subunit	193
638999209	684	39.04	1	547	1	558	0.0e+00	626	COG0143	Methionyl-tRNA synthetase	558
638999209	684	42.74	575	683	7	123	1.0e-24	108	COG0073	tRNA-binding EMAP/Myf domain	123
638999210	468	50.79	341	466	2	127	2.0e-34	140	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
638999210	468	51.94	1	331	1	333	3.0e-122	432	COG0836	Mannose-1-phosphate guanylyltransferase	333
638999211	265	46.4	2	221	54	264	4.0e-57	214	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
638999214	388	41.11	1	388	1	414	5.0e-125	441	COG1004	UDP-glucose 6-dehydrogenase	414
638999215	333	29.45	1	333	1	314	3.0e-55	209	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638999222	308	38.51	1	306	1	293	5.0e-68	251	COG1131	ABC-type multidrug transport system, ATPase component	293
638999223	168	28.57	12	135	8	130	1.0e-14	73	COG1832	Predicted CoA-binding protein	140
638999224	435	20.71	53	250	6	181	4.0e-18	86.3	COG3979	Chitodextrinase	181
638999225	701	18.97	39	381	48	324	3.0e-12	67.8	COG2273	Beta-glucanase, GH16 family	355
638999226	305	33.86	144	270	1	127	2.0e-21	96.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638999227	559	31.57	31	417	1	363	2.0e-53	204	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
638999228	819	21.78	6	672	15	666	2.0e-106	380	COG3250	Beta-galactosidase/beta-glucuronidase	808
638999229	118	25.69	1	108	1	109	2.0e-09	54.3	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
638999230	134	22.13	13	126	11	132	1.0e-06	45.7	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
638999231	652	33.21	385	652	100	366	2.0e-42	167	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
638999243	120	25.93	19	118	1	107	5.0e-12	63.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
638999244	100	48.39	2	94	1	93	5.0e-27	112	COG0776	Bacterial nucleoid DNA-binding protein	94
638999245	791	43.73	142	790	1	650	0.0e+00	639	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
638999246	338	57.43	1	336	3	335	5.0e-129	454	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
638999247	152	48.97	1	144	3	146	4.0e-45	173	COG1781	Aspartate carbamoyltransferase, regulatory subunit	153
638999248	316	50.32	5	308	1	313	3.0e-107	381	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
638999250	498	38.84	1	473	7	471	4.0e-130	458	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
638999251	484	44.74	135	475	3	331	6.0e-96	345	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
638999252	479	28.28	13	381	1	378	2.0e-56	213	COG0366	Glycosidase	505
638999253	305	22.74	4	300	5	282	2.0e-27	116	COG1307	Fatty acid-binding protein DegV (function unknown)	282
638999254	539	36.39	240	531	127	431	2.0e-65	243	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
638999256	322	21.71	39	322	4	303	8.0e-19	88.3	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
638999257	308	45.22	9	306	16	329	8.0e-64	237	COG0714	MoxR-like ATPase	329
638999258	505	52.15	1	484	4	470	0.0e+00	612	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
638999259	163	34.46	1	145	1	148	1.0e-18	86.1	COG1286	Uncharacterized membrane protein, required for colicin V production	182
638999261	401	39.53	1	401	1	423	2.0e-92	333	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
638999262	287	59.86	3	285	2	285	9.0e-117	413	COG0777	Acetyl-CoA carboxylase beta subunit	294
638999263	215	45.19	4	206	2	208	5.0e-57	213	COG0135	Phosphoribosylanthranilate isomerase	208
638999264	286	49.79	15	257	3	244	5.0e-79	287	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
638999265	937	27.97	17	764	29	718	2.0e-58	221	COG3170	Tfp pilus assembly protein FimV	755
638999266	361	29.13	1	356	12	333	5.0e-79	288	COG0136	Aspartate-semialdehyde dehydrogenase	334
638999267	362	53.59	1	357	2	345	5.0e-122	431	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
638999268	215	49.76	1	211	1	190	4.0e-72	264	COG0066	3-isopropylmalate dehydratase small subunit	191
638999269	475	55.91	1	470	1	421	0.0e+00	611	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
638999270	298	30.43	1	293	1	294	8.0e-37	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
638999272	295	34.8	1	289	1	295	2.0e-57	215	COG2974	DNA recombination-dependent growth factor C	303
638999277	674	54.19	1	667	4	667	0.0e+00	924	COG0272	NAD-dependent DNA ligase	667
638999278	363	22.4	1	357	2	321	5.0e-33	135	COG3115	Cell division protein ZipA, interacts with FtsZ	324
638999279	1166	36	1	1164	1	1163	0.0e+00	601	COG1196	Chromosome segregation ATPase	1163
638999280	401	24.33	2	255	5	253	4.0e-10	59.6	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
638999281	156	42.95	7	155	5	153	4.0e-38	150	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
638999282	177	25	32	155	1	126	9.0e-10	56.8	COG0526	Thiol-disulfide isomerase or thioredoxin	127
638999283	651	52.16	1	647	1	645	0.0e+00	604	COG1138	Cytochrome c biogenesis factor	648
638999284	147	51.75	1	143	1	143	3.0e-44	170	COG2332	Cytochrome c-type biogenesis protein CcmE	153
638999285	57	35.19	1	54	1	54	3.0e-10	56.8	COG3114	Heme exporter protein D	67
638999286	252	37.66	4	241	33	271	3.0e-34	138	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
638999287	223	51.39	7	222	6	221	8.0e-41	160	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
638999288	226	44.33	21	223	3	202	5.0e-49	187	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
638999290	112	38.89	2	89	3	92	4.0e-15	73.3	COG2257	Type III secretion system substrate exporter, FlhB-like	92
638999291	335	31.61	10	335	1	329	6.0e-71	261	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
638999292	211	47.87	1	210	2	211	2.0e-61	228	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
638999293	603	36.96	8	599	5	573	0.0e+00	557	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
638999294	166	49.38	8	162	1	159	6.0e-50	190	COG3265	Gluconate kinase	161
638999295	440	37.01	14	440	9	442	8.0e-79	287	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
638999296	180	31.71	17	179	11	167	3.0e-20	91.8	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
638999299	392	73.96	2	384	20	403	0.0e+00	659	COG1219	ATP-dependent protease Clp, ATPase subunit	408
638999300	209	74.35	19	209	3	193	1.0e-87	316	COG0740	ATP-dependent protease ClpP, protease subunit	200
638999301	437	44.44	1	432	1	440	4.0e-102	365	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
638999305	304	55.71	20	299	1	280	2.0e-107	382	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
638999306	165	47.88	3	165	2	158	4.0e-50	190	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
638999307	254	33.33	9	248	1	235	1.0e-42	166	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
638999309	208	54.55	9	205	5	202	4.0e-63	234	COG4445	tRNA isopentenyl-2-thiomethyl-A-37 hydroxylase MiaE (synthesis of 2-methylthio-cis-ribozeatin)	203
638999310	362	27.35	9	355	84	432	3.0e-72	265	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
638999311	140	42.45	1	138	2	137	4.0e-39	153	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
638999312	367	30.33	69	362	3	296	1.0e-44	174	COG2813	16S rRNA G1207 methylase RsmC	300
638999315	96	26.25	1	80	1	80	6.0e-09	52.3	COG1359	Quinol monooxygenase YgiN	100
638999316	713	37.89	8	389	4	377	1.0e-84	307	COG0116	23S rRNA G2445 N2-methylase RlmL	381
638999316	713	38.75	404	710	73	387	3.0e-76	280	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
638999317	63	52.17	1	46	9	54	9.0e-11	58.5	COG3130	Ribosome modulation factor	55
638999318	337	45.82	45	336	3	290	8.0e-85	307	COG0167	Dihydroorotate dehydrogenase	310
638999320	1606	45.39	1	1600	1	1591	0.0e+00	1640	COG2902	NAD-specific glutamate dehydrogenase	1592
638999323	553	36.69	1	548	1	510	0.0e+00	486	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
638999324	164	39.88	1	162	3	165	2.0e-28	118	COG3749	Uncharacterized conserved protein, DUF934 family	167
638999326	241	37.19	1	238	1	234	2.0e-53	202	COG2872	Ser-tRNA(Ala) deacylase AlaX (editing enzyme)	241
638999327	290	27.14	13	287	11	280	3.0e-20	92.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638999328	1031	25.32	5	1009	3	1007	0.0e+00	474	COG0841	Multidrug efflux pump subunit AcrB	1009
638999330	165	23.84	20	152	13	163	4.0e-08	51.1	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638999334	654	17.14	121	461	53	327	5.0e-09	56.6	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
638999335	181	48.04	1	179	12	189	3.0e-30	124	COG0558	Phosphatidylglycerophosphate synthase	192
638999336	611	48.76	7	608	1	581	0.0e+00	643	COG0322	Excinuclease UvrABC, nuclease subunit	581
638999337	214	40.95	3	210	2	211	1.0e-52	199	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
638999338	463	42.11	9	463	2	436	0.0e+00	468	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
638999339	686	29.93	420	680	2	279	4.0e-39	156	COG0515	Serine/threonine protein kinase	384
638999341	313	23.79	1	309	1	282	9.0e-32	131	COG1307	Fatty acid-binding protein DegV (function unknown)	282
638999342	457	37.03	30	452	43	454	1.0e-99	357	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
638999343	209	24.63	7	197	7	209	8.0e-24	103	COG0560	Phosphoserine phosphatase	212
638999344	241	43.28	4	236	15	245	7.0e-61	227	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
638999345	324	27.76	1	297	1	293	5.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
638999346	257	26.95	1	256	5	252	1.0e-07	50.8	COG0730	Uncharacterized membrane protein YfcA	258
638999348	363	59.09	8	359	1	351	0.0e+00	539	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
638999349	384	27.22	9	357	15	374	8.0e-29	121	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
638999351	200	45.77	1	197	1	199	3.0e-51	195	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
638999352	238	38.75	1	237	13	240	4.0e-43	168	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
638999353	146	67.36	1	141	1	144	3.0e-52	197	COG0328	Ribonuclease HI	154
638999355	569	29.73	389	496	1	110	6.0e-10	59.5	COG1388	LysM repeat	124
638999356	334	27.87	59	334	31	314	3.0e-42	166	COG0616	Periplasmic serine protease, ClpP class	317
638999357	103	23.76	1	101	19	118	3.0e-13	67	COG3255	Putative sterol carrier protein	134
638999359	338	33.02	5	315	9	314	1.0e-65	244	COG0042	tRNA-dihydrouridine synthase	323
638999360	307	36.72	4	304	1	238	6.0e-61	227	COG0176	Transaldolase	239
638999362	443	35.31	1	435	21	454	3.0e-110	392	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
638999363	77	42.11	1	75	1	72	4.0e-13	66.1	COG2991	Uncharacterized protein	77
638999364	344	41.07	8	338	5	336	3.0e-85	309	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
638999365	408	73.65	4	408	5	410	0.0e+00	701	COG2871	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF	410
638999366	202	71.78	1	202	1	198	2.0e-73	268	COG2209	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE	198
638999367	219	66.83	1	205	4	208	5.0e-80	290	COG1347	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD	208
638999368	257	46.36	1	257	3	261	2.0e-81	295	COG2869	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC	264
638999369	400	59.6	2	397	1	400	1.0e-117	417	COG1805	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB	400
638999370	445	60.63	1	445	1	447	0.0e+00	598	COG1726	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA	447
638999371	1151	50.13	11	1151	7	1137	0.0e+00	1360	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
638999373	249	39.27	5	247	19	262	9.0e-55	207	COG0005	Purine nucleoside phosphorylase	262
638999376	100	52.81	1	86	1	89	5.0e-22	95.8	COG0271	Stress-induced morphogen (activity unknown)	90
638999378	264	23.36	5	264	59	331	5.0e-19	88.3	COG0642	Signal transduction histidine kinase	336
638999379	237	23.56	46	232	10	211	3.0e-10	59.2	COG2755	Lysophospholipase L1 or related esterase	216
638999382	234	46.29	7	234	1	223	4.0e-64	237	COG4565	Response regulator of citrate/malate metabolism	224
638999383	540	41.87	6	537	6	534	0.0e+00	476	COG3290	Sensor histidine kinase regulating citrate/malate metabolism	537
638999384	327	34.27	8	327	3	318	5.0e-60	225	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
638999386	507	47.73	1	506	3	503	1.0e-130	460	COG3333	TctA family transporter	504
638999387	229	43.23	4	224	2	229	6.0e-55	207	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638999388	492	33.12	171	485	18	327	1.0e-34	141	COG0642	Signal transduction histidine kinase	336
638999396	261	42.04	13	256	1	245	7.0e-61	227	COG1414	DNA-binding transcriptional regulator, IclR family	246
638999397	213	22.5	1	159	1	151	2.0e-30	126	COG0698	Ribose 5-phosphate isomerase RpiB	151
638999399	215	44.29	1	209	3	211	3.0e-53	201	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
638999400	316	28.85	10	303	1	296	1.0e-40	160	COG0524	Sugar or nucleoside kinase, ribokinase family	311
638999401	252	41.57	5	250	1	251	3.0e-46	178	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638999402	413	23.37	2	409	23	432	4.0e-37	149	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
638999403	377	49.73	1	370	1	338	1.0e-117	416	COG3839	ABC-type sugar transport system, ATPase component	338
638999404	304	37.99	27	303	5	281	2.0e-59	222	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
638999405	295	42.61	4	283	8	290	5.0e-55	208	COG1175	ABC-type sugar transport system, permease component	295
638999407	374	18.52	26	374	92	401	2.0e-24	106	COG0823	Periplasmic component of the Tol biopolymer transport system	425
638999409	432	23.74	1	427	8	433	1.0e-39	157	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
638999410	293	36.21	3	290	2	290	5.0e-49	188	COG1175	ABC-type sugar transport system, permease component	295
638999411	280	32.73	4	278	10	278	6.0e-46	177	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
638999413	355	52.59	1	348	1	338	2.0e-124	439	COG3839	ABC-type sugar transport system, ATPase component	338
638999414	242	35.06	5	242	4	254	1.0e-33	136	COG0584	Glycerophosphoryl diester phosphodiesterase	257
638999415	256	36.29	2	238	1	237	2.0e-58	219	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
638999416	258	17.36	5	226	1	237	2.0e-13	69.7	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
638999418	331	20	68	295	9	227	1.0e-08	54.6	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
638999420	139	32.58	9	139	4	131	1.0e-19	88.5	COG3791	Uncharacterized conserved protein	133
638999422	316	23.62	11	310	3	281	8.0e-20	91.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
638999424	206	25.63	13	203	1	197	7.0e-27	113	COG4430	Uncharacterized conserved protein YdeI, YjbR/CyaY-like superfamily, DUF1801 family	200
638999425	491	22.66	148	462	40	362	2.0e-19	91.3	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
638999426	240	30.58	1	181	2	207	3.0e-25	108	COG0778	Nitroreductase	207
638999427	204	26.87	5	196	1	201	3.0e-17	81.8	COG0625	Glutathione S-transferase	211
638999428	109	57.01	1	107	8	114	2.0e-36	144	COG4898	Uncharacterized protein	115
638999429	305	24.5	5	293	2	296	2.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
638999430	316	18.81	2	300	1	303	6.0e-17	81.5	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638999432	587	26.23	65	587	65	594	3.0e-53	203	COG0729	Outer membrane translocation and assembly module TamA	594
638999434	135	27.81	1	133	4	151	4.0e-07	47.3	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
638999435	581	36.76	1	574	1	567	2.0e-120	426	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
638999436	583	36.98	2	575	1	567	4.0e-112	399	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
638999437	119	29.66	1	117	1	116	2.0e-20	91.2	COG3791	Uncharacterized conserved protein	133
638999440	222	58.37	1	221	1	219	6.0e-85	307	COG0036	Pentose-5-phosphate-3-epimerase	220
638999441	278	25.74	1	270	2	259	2.0e-31	129	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
638999443	303	22.89	4	283	9	277	1.0e-10	61.1	COG5006	Threonine/homoserine efflux transporter RhtA	292
638999446	318	35.09	4	316	2	305	3.0e-51	195	COG0524	Sugar or nucleoside kinase, ribokinase family	311
638999448	590	62.94	1	586	1	585	0.0e+00	904	COG0173	Aspartyl-tRNA synthetase	585
638999449	240	57.02	1	239	1	241	5.0e-89	320	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
638999450	171	50	3	152	1	150	1.0e-49	189	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
638999451	214	39.5	1	199	3	202	2.0e-40	159	COG2860	Uncharacterized membrane protein YeiH	209
638999452	201	45.32	1	201	1	200	2.0e-55	208	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
638999453	338	69	5	333	2	329	0.0e+00	521	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
638999454	213	38.81	1	201	13	213	3.0e-47	181	COG0811	Biopolymer transport protein ExbB/TolQ	216
638999455	144	36.96	5	142	7	137	9.0e-24	102	COG0848	Biopolymer transport protein ExbD	137
638999457	434	36.65	24	433	16	425	2.0e-78	286	COG0823	Periplasmic component of the Tol biopolymer transport system	425
638999458	188	35.64	1	188	6	188	3.0e-32	131	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
638999459	248	29.71	16	247	23	260	5.0e-27	114	COG1729	Periplasmic TolA-binding protein (function unknown)	262
638999460	227	56.44	4	225	1	219	5.0e-76	277	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
638999463	350	47.37	24	344	14	323	1.0e-109	389	COG0379	Quinolinate synthase	324
638999464	428	25.62	16	408	29	408	1.0e-33	137	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
638999465	61	29.03	1	61	17	78	3.0e-10	56.4	COG0425	TusA-related sulfurtransferase	78
638999466	368	32.56	23	365	17	351	2.0e-38	153	COG0628	Predicted PurR-regulated permease PerM	355
638999467	162	40.79	1	152	3	154	3.0e-43	167	COG1225	Peroxiredoxin	157
638999468	291	52.56	1	291	4	296	2.0e-91	329	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
638999470	255	30.47	1	232	4	258	4.0e-30	125	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
638999471	236	52.1	1	236	1	238	2.0e-79	289	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
638999473	209	25.42	1	177	1	177	1.0e-10	60.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638999474	633	21.56	261	619	8	365	8.0e-23	102	COG4585	Signal transduction histidine kinase	365
638999477	217	32.7	6	216	1	210	3.0e-40	158	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
638999479	481	35.15	13	208	1	202	7.0e-40	158	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
638999479	481	41.83	227	478	17	279	2.0e-49	190	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
638999483	238	44.71	30	237	4	204	2.0e-52	199	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
638999487	344	37.54	33	341	26	342	2.0e-64	239	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
638999488	358	43.73	3	354	2	355	3.0e-98	351	COG2933	23S rRNA C2498 (ribose-2'-O)-methylase RlmM	358
638999489	79	35.44	1	78	2	78	3.0e-18	83.4	COG0425	TusA-related sulfurtransferase	78
638999490	469	35.62	26	462	14	443	2.0e-69	257	COG0534	Na+-driven multidrug efflux pump	455
638999491	166	44.97	4	151	19	167	2.0e-44	171	COG3101	Elongation factor P hydroxylase (EF-P beta-lysylation pathway)	180
638999492	166	31	36	135	7	106	4.0e-17	81.1	COG3339	Uncharacterized membrane protein YkvA, DUF1232 family	116
638999493	290	47.89	5	288	2	285	9.0e-84	303	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
638999494	534	40.08	29	493	31	497	2.0e-106	380	COG0513	Superfamily II DNA and RNA helicase	513
638999495	379	31.73	34	278	39	304	8.0e-37	148	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
638999497	323	34.72	1	322	1	325	2.0e-48	186	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
638999499	405	38.02	8	403	1	393	5.0e-97	348	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
638999500	133	58.02	4	133	1	131	1.0e-55	208	COG0229	Peptide methionine sulfoxide reductase MsrB	140
638999501	223	23.12	30	200	19	175	5.0e-24	104	COG2818	3-methyladenine DNA glycosylase Tag	188
638999502	206	30.34	29	195	30	206	5.0e-11	61.1	COG3714	Uncharacterized membrane protein YhhN	212
638999503	300	52.12	1	299	4	309	2.0e-114	405	COG0078	Ornithine carbamoyltransferase	310
638999504	107	56.19	1	104	1	105	1.0e-42	164	COG0278	Glutaredoxin-related protein	105
638999505	256	43.7	3	250	2	254	1.0e-64	239	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
638999507	183	48.65	1	183	11	194	1.0e-53	202	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
638999508	658	32.89	279	658	32	408	1.0e-42	168	COG0840	Methyl-accepting chemotaxis protein	408
638999509	372	28.61	4	369	1	364	5.0e-94	337	COG1932	Phosphoserine aminotransferase	365
638999511	716	28.92	16	648	101	673	1.0e-108	387	COG0209	Ribonucleotide reductase alpha subunit	696
638999513	477	56.99	1	477	4	482	0.0e+00	703	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
638999514	428	53.46	1	426	60	474	0.0e+00	486	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
638999516	139	45.54	2	112	1	112	1.0e-30	125	COG0360	Ribosomal protein S6	112
638999517	75	79.41	1	68	8	75	9.0e-24	101	COG0238	Ribosomal protein S18	75
638999520	149	46.31	1	149	1	148	4.0e-39	153	COG0359	Ribosomal protein L9	148
638999521	472	46.91	26	462	1	434	0.0e+00	501	COG0305	Replicative DNA helicase	435
638999522	358	48.63	1	358	1	359	2.0e-107	382	COG0787	Alanine racemase	360
638999524	496	34.45	4	476	2	429	2.0e-96	346	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
638999525	438	59.86	10	438	5	435	8.0e-118	417	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
638999526	176	46.29	1	175	5	179	9.0e-47	179	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
638999528	144	23.97	1	144	2	146	2.0e-08	51.6	COG3909	Cytochrome c556	147
638999529	233	59.53	11	223	7	221	3.0e-85	308	COG0692	Uracil DNA glycosylase	223
638999530	640	67.95	1	640	1	649	0.0e+00	877	COG2766	Predicted Ser/Thr protein kinase	649
638999531	427	56.24	4	425	2	418	0.0e+00	490	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
638999532	522	63.01	17	507	5	490	0.0e+00	653	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
638999533	322	47.69	1	322	1	322	1.0e-97	350	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
638999534	165	26.95	7	153	22	183	1.0e-13	69.6	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
638999535	180	48.48	8	170	5	168	5.0e-50	190	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
638999536	159	55.06	1	158	1	157	9.0e-56	209	COG0315	Molybdenum cofactor biosynthesis enzyme	157
638999537	83	41.46	5	83	3	84	1.0e-16	78.1	COG1977	Molybdopterin converting factor, small subunit	84
638999538	149	44.59	1	148	3	149	3.0e-45	174	COG0314	Molybdopterin synthase catalytic subunit	149
638999539	238	23.51	1	231	4	254	2.0e-26	112	COG0725	ABC-type molybdate transport system, periplasmic component	258
638999540	223	48.17	5	222	8	225	1.0e-52	200	COG4149	ABC-type molybdate transport system, permease component	225
638999541	348	27.44	28	336	28	350	5.0e-35	142	COG4148	ABC-type molybdate transport system, ATPase component	352
638999542	877	23.4	5	871	3	929	2.0e-36	148	COG5373	Uncharacterized membrane protein	931
638999543	448	37.53	21	448	1	411	2.0e-123	435	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
638999545	319	19.19	42	305	1	255	8.0e-21	94.6	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
638999546	209	29.27	10	203	17	221	2.0e-12	65.9	COG0705	Membrane associated serine protease, rhomboid family	228
638999550	521	33.58	1	515	2	509	8.0e-90	324	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
638999551	331	33.13	1	320	1	326	2.0e-52	199	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
638999556	221	24.88	10	202	6	201	3.0e-18	85.3	COG0625	Glutathione S-transferase	211
638999557	154	34	1	149	6	154	3.0e-25	107	COG1522	DNA-binding transcriptional regulator, Lrp family	154
638999560	590	27.9	8	238	16	243	9.0e-27	115	COG3176	Putative hemolysin	292
638999563	363	61.56	1	363	1	372	0.0e+00	508	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
638999564	215	52.88	23	213	1	190	4.0e-71	260	COG0193	Peptidyl-tRNA hydrolase	190
638999565	208	46.32	5	99	2	93	7.0e-19	87.2	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
638999566	309	56.73	1	309	5	314	3.0e-116	411	COG0462	Phosphoribosylpyrophosphate synthetase	314
638999567	286	41.38	2	278	1	287	6.0e-78	284	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
638999568	189	28.12	12	184	14	205	9.0e-25	106	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
638999569	574	18.95	374	563	49	235	2.0e-06	48.1	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
638999570	419	47.73	1	419	1	413	1.0e-125	443	COG0373	Glutamyl-tRNA reductase	414
638999571	361	67.77	1	361	1	363	0.0e+00	547	COG0216	Protein chain release factor A	363
638999572	275	45	16	274	19	278	1.0e-66	246	COG2890	Methylase of polypeptide chain release factors	280
638999573	229	35.04	94	229	28	157	2.0e-23	102	COG2030	Acyl dehydratase	159
638999574	320	36.34	1	315	1	319	2.0e-76	279	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
638999576	615	34.62	252	615	50	408	4.0e-48	186	COG0840	Methyl-accepting chemotaxis protein	408
638999577	719	53.68	395	715	1	325	2.0e-108	386	COG0280	Phosphotransacetylase	327
638999578	392	53.69	5	392	3	393	0.0e+00	502	COG0282	Acetate kinase	396
638999581	116	29	15	113	2	101	4.0e-14	70.3	COG0607	Rhodanese-related sulfurtransferase	110
638999584	211	23.12	8	191	28	218	2.0e-14	72.7	COG4117	Thiosulfate reductase cytochrome b subunit	221
638999585	643	53.82	35	635	2	583	0.0e+00	790	COG0441	Threonyl-tRNA synthetase	589
638999586	153	66.23	1	153	23	176	2.0e-50	191	COG0290	Translation initiation factor IF-3	176
638999587	64	54.69	1	63	1	64	1.0e-09	54.8	COG0291	Ribosomal protein L35	65
638999588	118	77.97	1	118	1	118	5.0e-39	153	COG0292	Ribosomal protein L20	118
638999589	337	46.59	1	335	1	329	0.0e+00	502	COG1087	UDP-glucose 4-epimerase	329
638999590	153	31.03	6	150	3	141	1.0e-19	89.2	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
638999591	342	28.36	8	342	15	303	5.0e-57	215	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
638999592	647	27.23	11	645	47	706	5.0e-95	342	COG0557	Exoribonuclease R	706
638999595	456	28.91	240	448	18	215	6.0e-29	122	COG2114	Adenylate cyclase, class 3	227
638999597	124	31.2	1	121	2	126	2.0e-11	61.4	COG3094	Uncharacterized membrane protein SirB2	129
638999598	369	27.15	71	368	11	306	3.0e-30	126	COG0668	Small-conductance mechanosensitive channel	316
638999603	337	37.54	3	333	1	312	2.0e-76	279	COG1619	Muramoyltetrapeptide carboxypeptidase LdcA (peptidoglycan recycling)	313
638999604	70	63.16	3	59	1	57	4.0e-17	79.5	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
638999605	86	57.32	1	82	6	87	2.0e-27	113	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
638999606	461	50.64	2	459	1	463	0.0e+00	577	COG0215	Cysteinyl-tRNA synthetase	464
638999608	178	33.69	4	176	2	187	2.0e-22	99.1	COG0406	Broad specificity phosphatase PhoE	208
638999609	245	30.08	1	245	1	242	1.0e-30	126	COG0368	Cobalamin synthase	246
638999610	336	39.34	6	335	17	335	1.0e-69	256	COG2038	NaMN:DMB phosphoribosyltransferase	347
638999611	177	41.71	3	168	1	175	4.0e-37	147	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
638999613	178	34.55	1	159	14	176	3.0e-32	131	COG2320	GrpB domain, predicted nucleotidyltransferase, UPF0157 family	185
638999614	246	19.73	28	245	47	266	3.0e-13	69.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
638999615	200	29.56	3	198	2	204	1.0e-22	99	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
638999617	475	35.92	1	472	1	457	4.0e-102	365	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
638999619	389	26.61	13	389	12	383	5.0e-50	192	COG0006	Xaa-Pro aminopeptidase	384
638999621	251	20.41	5	238	48	285	5.0e-19	88.5	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
638999622	316	20.78	9	305	38	342	4.0e-19	89	COG3239	Fatty acid desaturase	343
638999626	108	26.92	12	107	1	104	2.0e-13	68.1	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
638999630	232	29.78	5	229	20	225	7.0e-16	77.7	COG2801	Transposase InsO and inactivated derivatives	232
638999633	162	32.54	28	151	8	131	1.0e-14	72.9	COG1917	Cupin domain protein related to quercetin dioxygenase	131
638999634	237	35	140	237	22	120	5.0e-07	48.5	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
638999635	303	37.8	1	289	6	294	4.0e-60	225	COG1230	Co/Zn/Cd efflux system component	296
638999636	281	27.82	2	267	44	303	2.0e-31	129	COG0385	Predicted Na+-dependent transporter	319
638999637	292	38.98	2	288	8	299	2.0e-50	193	COG1575	1,4-dihydroxy-2-naphthoate octaprenyltransferase	303
638999638	351	28.8	45	351	18	298	8.0e-27	114	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
638999639	401	23.17	49	388	54	384	2.0e-11	63.7	COG2814	Predicted arabinose efflux permease, MFS family	394
638999640	425	21.28	1	424	5	417	6.0e-50	191	COG0443	Molecular chaperone DnaK (HSP70)	579
638999642	213	48.34	6	213	14	224	2.0e-43	168	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
638999643	403	25.71	263	400	3	134	1.0e-15	78.1	COG1765	Uncharacterized OsmC-related protein	137
638999644	369	32.34	9	369	5	359	2.0e-59	223	COG0787	Alanine racemase	360
638999645	378	33.25	4	375	14	392	3.0e-76	279	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
638999646	249	60.32	1	247	2	240	4.0e-103	367	COG1126	ABC-type polar amino acid transport system, ATPase component	240
638999647	217	35.59	1	217	1	222	8.0e-39	153	COG0765	ABC-type amino acid transport system, permease component	222
638999648	218	38.32	3	215	8	221	1.0e-42	166	COG0765	ABC-type amino acid transport system, permease component	222
638999649	262	33.33	1	259	1	267	3.0e-36	145	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
638999650	324	21.21	13	307	1	291	5.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
638999653	355	22.88	7	325	1	274	3.0e-29	123	COG1082	Sugar phosphate isomerase/epimerase	274
638999654	351	30.2	1	349	26	342	1.0e-41	163	COG0673	Predicted dehydrogenase	342
638999655	510	46.99	1	495	4	499	0.0e+00	544	COG1129	ABC-type sugar transport system, ATPase component	500
638999656	327	47	24	322	11	306	2.0e-56	213	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
638999657	324	31.4	1	324	5	322	3.0e-37	149	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
638999659	286	35.77	9	282	1	267	2.0e-54	206	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
638999660	516	44.98	288	516	60	286	1.0e-64	240	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
638999661	364	18.85	6	361	15	362	7.0e-31	128	COG0687	Spermidine/putrescine-binding periplasmic protein	363
638999662	365	47.32	9	362	5	352	4.0e-116	411	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
638999663	176	20.83	13	174	10	177	7.0e-13	66.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638999664	156	24.49	6	152	1	129	4.0e-09	54.5	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
638999666	237	41.95	5	237	7	239	4.0e-67	247	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
638999667	358	35.82	1	322	3	335	5.0e-76	278	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
638999669	734	74.18	3	734	11	730	0.0e+00	1196	COG0376	Catalase (peroxidase I)	730
638999671	644	35.4	78	617	1	522	3.0e-117	416	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
638999672	417	17.23	150	415	78	330	9.0e-09	55.2	COG0642	Signal transduction histidine kinase	336
638999673	142	25	2	125	20	151	4.0e-14	70.3	COG0835	Chemotaxis signal transduction protein	165
638999674	310	22.95	33	249	2	229	5.0e-16	78.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638999675	473	30.49	164	466	31	328	6.0e-36	145	COG0642	Signal transduction histidine kinase	336
638999676	224	44.1	3	224	2	229	7.0e-52	197	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
638999678	298	33.1	8	150	17	158	2.0e-23	103	COG0835	Chemotaxis signal transduction protein	165
638999679	163	57.06	1	163	4	165	2.0e-47	181	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
638999680	131	32.77	7	123	1	117	2.0e-13	68.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
638999681	292	49.66	1	289	1	290	1.0e-98	353	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
638999683	1110	33.28	506	1110	6	548	9.0e-129	455	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
638999683	1110	34.48	159	378	20	247	1.0e-52	202	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
638999683	1110	34.78	2	139	8	143	5.0e-30	127	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
638999685	392	30.18	1	390	1	381	3.0e-72	266	COG0006	Xaa-Pro aminopeptidase	384
638999689	340	46.04	1	340	9	339	7.0e-79	287	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
638999690	359	39.09	3	353	1	316	3.0e-87	315	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
638999691	937	24.37	28	456	1	412	1.0e-44	175	COG0612	Predicted Zn-dependent peptidase	438
638999692	155	38.36	1	145	1	146	1.0e-30	125	COG1959	DNA-binding transcriptional regulator, IscR family	150
638999693	397	37.24	14	396	14	396	8.0e-62	231	COG3213	Uncharacterized protein involved in response to NO	396
638999694	235	28.04	11	218	2	214	1.0e-25	110	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
638999695	105	47	6	104	8	104	4.0e-18	83.1	COG2863	Cytochrome c553	121
638999696	696	39.86	33	447	52	480	3.0e-98	353	COG3901	Regulator of nitric oxide reductase transcription	482
638999697	632	61.94	20	631	11	637	0.0e+00	838	COG4263	Nitrous oxide reductase	637
638999698	423	42.93	39	419	30	400	4.0e-98	351	COG3420	Nitrous oxidase accessory protein NosD, contains tandem CASH domains	408
638999699	309	42.17	6	229	4	224	2.0e-58	219	COG1131	ABC-type multidrug transport system, ATPase component	293
638999700	272	24.73	4	270	3	275	1.0e-10	60.5	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
638999701	184	36.18	4	153	6	157	3.0e-33	135	COG4314	Nitrous oxide reductase accessory protein NosL	176
638999703	444	28.18	1	433	28	454	7.0e-46	178	COG0534	Na+-driven multidrug efflux pump	455
638999704	271	37.72	158	271	13	126	6.0e-23	101	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638999705	165	30.94	18	154	1	130	3.0e-13	68.4	COG5628	Predicted acetyltransferase	143
638999708	135	35.88	5	134	4	131	9.0e-21	92.8	COG3791	Uncharacterized conserved protein	133
638999710	349	31.28	1	194	2	187	7.0e-30	125	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
638999711	251	36.64	1	250	1	251	2.0e-39	155	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
638999712	407	45.43	17	407	1	392	2.0e-79	289	COG0183	Acetyl-CoA acetyltransferase	392
638999714	545	31.56	6	540	2	527	2.0e-105	376	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
638999715	1149	24.63	7	469	5	461	5.0e-48	187	COG0591	Na+/proline symporter	493
638999715	1149	27.2	1027	1147	2	124	1.0e-10	62.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
638999715	1149	27.31	742	1010	67	329	1.0e-33	139	COG0642	Signal transduction histidine kinase	336
638999717	243	49.32	1	221	1	218	3.0e-63	235	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
638999718	471	20.62	34	467	3	419	6.0e-35	142	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
638999721	142	42.28	1	122	2	120	2.0e-27	115	COG1516	Flagellin-specific chaperone FliS	132
638999722	485	42.71	1	482	1	460	2.0e-115	409	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638999724	468	44.54	1	463	5	464	0.0e+00	469	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638999725	143	35.48	51	143	14	105	7.0e-14	70	COG1677	Flagellar hook-basal body complex protein FliE	105
638999728	352	47.13	20	349	7	337	3.0e-85	309	COG1536	Flagellar motor switch protein FliG	339
638999729	382	23.08	20	259	3	234	3.0e-15	76.6	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
638999730	486	58.18	18	442	16	441	0.0e+00	594	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
638999731	144	31.69	1	142	1	142	6.0e-09	53.8	COG2882	Flagellar biosynthesis chaperone FliJ	148
638999732	99	17.53	5	99	8	104	5.0e-09	52.7	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
638999736	177	26.7	2	177	1	159	4.0e-17	81.1	COG1580	Flagellar basal body-associated protein FliL	159
638999737	360	40.12	1	326	1	328	7.0e-91	327	COG1868	Flagellar motor switch protein FliM	332
638999738	165	42.06	30	154	11	136	2.0e-22	98.5	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
638999739	144	29.82	23	129	21	134	2.0e-16	78.8	COG3190	Flagellar biogenesis protein FliO	137
638999740	221	58.26	3	220	32	248	1.0e-65	242	COG1338	Flagellar biosynthetic protein FliP	248
638999741	89	41.57	1	89	1	89	4.0e-12	63.2	COG1987	Flagellar biosynthesis protein FliQ	89
638999742	263	38.13	7	263	1	256	1.0e-42	166	COG1684	Flagellar biosynthesis protein FliR	258
638999743	378	44.51	2	365	1	363	1.0e-114	406	COG1377	Flagellar biosynthesis protein FlhB	363
638999744	234	33.91	5	228	14	246	6.0e-28	117	COG3503	Uncharacterized membrane protein	323
638999747	344	42.53	1	344	1	316	2.0e-86	313	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
638999749	258	27.97	1	231	10	252	5.0e-17	81.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
638999750	266	53.31	4	260	1	253	8.0e-76	277	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
638999752	301	31.88	3	295	2	293	7.0e-43	167	COG0583	DNA-binding transcriptional regulator, LysR family	297
638999757	315	42.17	3	166	1	165	2.0e-36	146	COG0835	Chemotaxis signal transduction protein	165
638999758	273	31.92	5	258	3	257	1.0e-33	136	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
638999759	628	30.45	329	608	3	288	5.0e-27	116	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
638999760	695	30.58	270	668	13	408	5.0e-40	159	COG0840	Methyl-accepting chemotaxis protein	408
638999761	1037	26.63	1	1030	2	1008	0.0e+00	617	COG0841	Multidrug efflux pump subunit AcrB	1009
638999762	362	21.25	4	346	1	364	4.0e-17	82.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
638999763	629	43.26	1	526	1	528	0.0e+00	518	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
638999768	282	32.12	13	282	1	267	8.0e-55	207	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
638999769	699	31.65	282	675	17	408	5.0e-38	153	COG0840	Methyl-accepting chemotaxis protein	408
638999770	180	28.76	27	179	9	161	5.0e-27	113	COG0835	Chemotaxis signal transduction protein	165
638999773	318	41.23	3	315	1	316	2.0e-71	263	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
638999775	142	38.52	6	139	5	139	4.0e-30	123	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
638999777	761	24.92	182	741	11	632	4.0e-55	210	COG1199	Rad3-related DNA helicase	654
638999781	1050	33.33	11	1049	4	1073	0.0e+00	875	COG0587	DNA polymerase III, alpha subunit	1139
638999783	323	29.84	10	319	1	262	1.0e-51	197	COG0171	NH3-dependent NAD+ synthetase	268
638999784	503	35.33	1	499	11	527	2.0e-104	373	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
638999786	638	27.75	1	608	1	521	4.0e-100	359	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
638999787	507	61.32	1	499	1	498	0.0e+00	641	COG2986	Histidine ammonia-lyase	498
638999788	563	74.46	1	556	2	557	0.0e+00	956	COG2987	Urocanate hydratase	561
638999789	250	33.47	5	239	9	232	4.0e-46	178	COG2188	DNA-binding transcriptional regulator, GntR family	236
638999790	420	37.96	13	419	1	404	7.0e-91	328	COG1228	Imidazolonepropionase or related amidohydrolase	406
638999791	320	30.13	24	319	1	298	4.0e-45	175	COG0010	Arginase family enzyme	305
638999792	189	24.69	12	171	16	174	6.0e-10	57.7	COG3945	Hemerythrin-like domain	189
638999794	202	28.14	6	198	7	200	1.0e-14	73.4	COG1776	Chemotaxis protein CheY-P-specific phosphatase CheC	203
638999796	933	47.88	324	933	1	593	0.0e+00	645	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
638999797	315	29.59	1	280	5	295	3.0e-37	149	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
638999798	456	31.07	137	340	3	201	1.0e-38	154	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
638999800	159	30.97	5	159	1	155	3.0e-25	108	COG3915	Uncharacterized protein	155
638999801	643	21.29	203	348	16	170	8.0e-08	52.8	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638999801	643	37.39	389	625	17	251	2.0e-52	201	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
638999802	269	19.33	5	243	4	272	8.0e-11	61.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
638999803	303	30.67	1	298	1	288	1.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
638999804	693	53.21	1	684	2	675	0.0e+00	840	COG1200	RecG-like helicase	677
638999805	461	27.57	167	409	1	238	2.0e-42	166	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
638999809	354	19.23	1	354	2	381	1.0e-15	77.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638999813	351	26.85	1	314	6	319	6.0e-33	134	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
638999814	381	17	1	340	65	400	1.0e-07	51.3	COG3307	O-antigen ligase	424
638999818	353	19.94	1	352	1	361	7.0e-22	98.5	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
638999819	350	21.55	1	350	2	362	2.0e-24	106	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
638999820	360	17.34	1	357	2	342	3.0e-19	89.6	COG3765	LPS O-antigen chain length determinant protein, WzzB/FepE family	347
638999821	256	24.21	3	254	14	263	1.0e-25	110	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
638999822	237	36.67	5	228	1	238	7.0e-59	220	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
638999825	353	66.95	4	350	1	337	0.0e+00	576	COG1088	dTDP-D-glucose 4,6-dehydratase	340
638999826	295	47.4	1	289	1	280	2.0e-85	309	COG1091	dTDP-4-dehydrorhamnose reductase	281
638999827	315	57.34	16	301	2	284	3.0e-113	401	COG1209	dTDP-glucose pyrophosphorylase	286
638999828	185	54.55	1	176	1	173	8.0e-60	223	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
638999829	1009	28.86	208	445	5	245	2.0e-25	111	COG1216	Glycosyltransferase, GT2 family	305
638999830	520	20.69	1	279	4	291	2.0e-12	67.8	COG1216	Glycosyltransferase, GT2 family	305
638999832	480	36.84	2	389	4	394	4.0e-64	239	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
638999834	530	19.33	202	516	89	377	1.0e-12	68.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
638999836	401	24.91	120	401	5	277	8.0e-24	104	COG1216	Glycosyltransferase, GT2 family	305
638999837	270	21.03	1	270	3	284	3.0e-18	86	COG1216	Glycosyltransferase, GT2 family	305
638999838	307	18.69	10	298	3	273	9.0e-12	64.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
638999839	454	35.85	1	454	5	459	9.0e-96	344	COG1109	Phosphomannomutase	464
638999841	463	31.15	156	456	38	329	2.0e-32	133	COG0642	Signal transduction histidine kinase	336
638999843	455	45.51	16	452	6	462	0.0e+00	488	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
638999846	249	33.62	4	231	78	288	9.0e-50	190	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
638999848	331	27.16	4	327	9	302	9.0e-59	220	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
638999849	295	52.38	15	287	10	281	2.0e-89	322	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
638999852	550	26.73	26	543	1	561	7.0e-55	208	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
638999853	483	37.42	312	469	16	177	1.0e-32	134	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638999854	355	32.24	132	344	40	244	4.0e-25	109	COG1360	Flagellar motor protein MotB	244
638999855	446	63.45	1	446	1	441	0.0e+00	633	COG3724	Succinylarginine dihydrolase	442
638999856	489	39.13	5	461	2	455	3.0e-112	399	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638999857	349	51.75	1	342	2	336	3.0e-117	415	COG3138	Arginine/ornithine N-succinyltransferase beta subunit	336
638999858	335	37.35	1	335	1	336	2.0e-78	286	COG3138	Arginine/ornithine N-succinyltransferase beta subunit	336
638999859	402	56.33	1	402	5	402	0.0e+00	549	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
638999861	319	40.06	1	310	9	320	2.0e-72	266	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
638999862	388	22.94	3	361	4	381	3.0e-21	96.5	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
638999863	253	29.92	5	235	5	246	8.0e-28	117	COG0584	Glycerophosphoryl diester phosphodiesterase	257
638999864	182	29.19	3	182	1	185	2.0e-22	98.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
638999865	165	39.51	4	160	13	174	2.0e-37	148	COG0684	Regulator of RNase E activity RraA	210
638999869	887	21.02	2	439	37	472	3.0e-59	223	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
638999869	887	46.72	445	853	1	377	2.0e-115	410	COG1454	Alcohol dehydrogenase, class IV	377
638999871	579	34.1	1	488	1	512	1.0e-90	327	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
638999873	521	30.88	113	520	3	407	2.0e-44	174	COG0840	Methyl-accepting chemotaxis protein	408
638999874	336	41.34	17	336	4	331	1.0e-46	180	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
638999875	329	45.73	5	326	5	330	2.0e-50	193	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
638999876	303	30.6	23	296	34	308	6.0e-41	161	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
638999878	316	23.83	16	307	31	319	3.0e-30	126	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
638999879	342	40.85	20	339	5	330	1.0e-48	187	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
638999880	332	47.53	12	330	8	329	5.0e-54	205	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
638999881	281	49.42	7	262	1	257	4.0e-90	324	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
638999883	471	38.07	1	441	2	454	4.0e-104	372	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
638999884	149	37.69	15	144	7	134	8.0e-27	112	COG4446	Uncharacterized conserved protein, DUF1499 family	141
638999885	142	39.13	19	130	2	116	3.0e-09	54.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
638999886	68	64.62	5	68	3	67	1.0e-21	94.4	COG1278	Cold shock protein, CspA family	67
638999888	333	31.21	1	320	2	324	1.0e-41	164	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
638999890	336	47.77	2	334	1	334	4.0e-108	384	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
638999892	455	28.99	1	440	4	440	3.0e-66	246	COG2211	Na+/melibiose symporter or related transporter	467
638999895	491	37.88	58	480	2	405	1.0e-106	380	COG1252	NADH dehydrogenase, FAD-containing subunit	405
638999896	468	32.94	197	450	2	253	7.0e-52	198	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
638999899	543	28.32	145	536	21	408	8.0e-39	155	COG0840	Methyl-accepting chemotaxis protein	408
638999901	472	45.3	2	472	10	488	0.0e+00	507	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
638999905	543	28.79	37	167	8	139	2.0e-16	80.8	COG4642	Uncharacterized conserved protein	139
638999906	581	28.43	47	458	1	383	3.0e-85	309	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
638999907	163	38.96	4	157	3	154	4.0e-29	120	COG1522	DNA-binding transcriptional regulator, Lrp family	154
638999908	172	27.06	1	168	2	165	6.0e-19	87.2	COG0597	Lipoprotein signal peptidase	167
638999909	367	27.48	19	351	2	345	3.0e-32	133	COG4782	Esterase/lipase superfamily enzyme	377
638999910	142	27.93	25	134	6	112	1.0e-11	62.3	COG3791	Uncharacterized conserved protein	133
638999911	203	35.05	9	202	55	264	2.0e-40	158	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
638999912	214	21.57	11	203	7	210	3.0e-17	81.8	COG0625	Glutathione S-transferase	211
638999913	805	29.86	26	374	47	387	3.0e-55	210	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
638999914	221	25.54	1	184	6	182	2.0e-07	49.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638999919	663	28.38	1	515	4	515	4.0e-49	189	COG2268	Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain	548
638999924	157	32.46	48	157	32	143	5.0e-10	57.3	COG3789	Uncharacterized protein YjfI, DUF2170 family	146
638999928	727	35.2	551	727	5	180	2.0e-32	134	COG1704	Uncharacterized conserved protein	185
638999929	250	37.25	2	245	1	243	6.0e-64	237	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
638999930	204	23.15	7	196	4	206	4.0e-18	85	COG1011	FMN phosphatase YigB, HAD superfamily	229
638999931	326	29.08	1	323	3	337	9.0e-45	174	COG0673	Predicted dehydrogenase	342
638999934	163	36.67	35	92	5	64	1.0e-12	66	COG1983	Phage shock protein PspC (stress-responsive transcriptional regulator)	70
638999936	225	35	1	219	1	220	5.0e-25	108	COG1842	Phage shock protein A	225
638999940	112	71.43	1	112	1	112	3.0e-38	149	COG0347	Nitrogen regulatory protein PII	112
638999941	185	49.45	4	184	15	195	3.0e-54	204	COG0740	ATP-dependent protease ClpP, protease subunit	200
638999944	291	37.85	7	287	6	291	4.0e-58	218	COG2971	BadF-type ATPase, related to human N-acetylglucosamine kinase	301
638999945	256	42.13	22	253	5	236	4.0e-52	198	COG2188	DNA-binding transcriptional regulator, GntR family	236
638999948	263	37.9	1	242	1	237	4.0e-53	201	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
638999951	170	44.94	6	163	4	160	8.0e-42	163	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
638999952	265	54.37	5	265	2	264	5.0e-94	337	COG0413	Ketopantoate hydroxymethyltransferase	268
638999953	282	50.53	1	281	1	285	3.0e-96	345	COG0414	Panthothenate synthetase	285
638999954	126	49.19	3	126	2	125	5.0e-42	163	COG0853	Aspartate 1-decarboxylase	126
638999955	547	46.14	46	535	3	445	0.0e+00	462	COG0166	Glucose-6-phosphate isomerase	446
638999956	176	18.92	1	106	1	111	2.0e-06	45.8	COG2165	Type II secretory pathway, pseudopilin PulG	149
638999966	215	32	1	199	3	227	6.0e-19	87.6	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
638999967	100	35	1	99	1	100	9.0e-22	94.9	COG0011	Uncharacterized conserved protein YqgV, UPF0045/DUF77 family	100
638999968	297	28.19	4	296	1	297	6.0e-26	111	COG0583	DNA-binding transcriptional regulator, LysR family	297
638999969	619	21.67	436	614	2	178	3.0e-13	70.5	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
638999970	182	65.75	1	181	2	182	7.0e-80	289	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
638999971	340	42.52	36	334	4	294	8.0e-81	294	COG1162	Putative ribosome biogenesis GTPase RsgA	301
638999976	1278	36.08	138	970	1	743	0.0e+00	732	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
638999976	1278	40.15	1021	1278	1	231	9.0e-71	262	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
638999977	477	35.28	37	454	14	438	2.0e-86	313	COG4623	Membrane-bound lytic murein transglycosylase MltF	473
638999979	276	54.91	2	276	13	287	4.0e-114	404	COG0788	Formyltetrahydrofolate hydrolase	287
638999980	135	46.67	16	134	1	120	6.0e-17	79.7	COG1734	RNA polymerase-binding transcription factor DksA	120
638999983	139	19.58	2	139	12	154	1.0e-07	49.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
638999984	365	41.93	3	345	1	352	2.0e-86	312	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
638999985	324	61.06	19	320	1	302	0.0e+00	473	COG0320	Lipoate synthase	306
638999986	214	53.08	5	213	6	216	5.0e-75	274	COG0321	Lipoate-protein ligase B	221
638999987	92	34.07	2	92	1	90	2.0e-13	67.6	COG2921	Putative lipoic acid-binding regulatory protein	90
638999988	394	41.88	14	392	12	389	1.0e-103	370	COG1686	D-alanyl-D-alanine carboxypeptidase	389
638999990	382	36.65	24	362	5	347	1.0e-112	399	COG0621	tRNA A37 methylthiotransferase MiaB	437
638999992	345	36.67	223	341	9	127	2.0e-14	73.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
638999993	676	42.7	5	359	2	362	1.0e-103	370	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
638999997	140	31.91	1	140	1	140	5.0e-25	107	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
638999998	498	45.62	1	497	1	501	0.0e+00	542	COG3534	Alpha-L-arabinofuranosidase	501
639000001	258	46.46	4	255	3	255	2.0e-87	315	COG0024	Methionine aminopeptidase	255
639000005	358	25.59	38	321	107	402	1.0e-18	87.7	COG0840	Methyl-accepting chemotaxis protein	408
639000006	95	19.57	1	92	10	101	1.0e-08	51.2	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
639000007	562	23.97	124	381	98	362	2.0e-18	88.2	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
639000009	651	39.24	1	637	2	705	0.0e+00	578	COG0643	Chemotaxis protein histidine kinase CheA	716
639000010	161	41.06	8	158	15	165	5.0e-37	146	COG0835	Chemotaxis signal transduction protein	165
639000011	883	43.34	538	835	86	408	1.0e-53	205	COG0840	Methyl-accepting chemotaxis protein	408
639000012	278	41.54	13	276	1	268	4.0e-69	254	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
639000013	204	39.13	17	176	1	161	3.0e-49	188	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
639000014	349	52.15	1	346	1	349	3.0e-103	368	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
639000018	298	37.59	5	289	10	294	4.0e-53	201	COG4240	Pantothenate kinase-related protein Tda10 (topoisomerase I damage affected protein)	300
639000019	284	32.47	12	276	3	267	1.0e-33	137	COG3769	Predicted mannosyl-3-phosphoglycerate phosphatase, HAD superfamily	274
639000021	588	18.56	99	560	43	505	6.0e-25	109	COG0366	Glycosidase	505
639000022	317	48.45	147	305	20	179	7.0e-38	151	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
639000023	256	32.53	17	251	3	246	1.0e-35	143	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
639000024	235	56.78	2	233	8	241	4.0e-83	301	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
639000025	438	39.02	5	423	2	420	2.0e-89	323	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
639000026	881	56.67	1	843	1	804	0.0e+00	1025	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
639000027	366	50.69	7	365	4	364	1.0e-119	423	COG1932	Phosphoserine aminotransferase	365
639000028	372	41.67	8	102	2	95	4.0e-18	86.2	COG1605	Chorismate mutase	101
639000028	372	46.74	101	372	2	277	7.0e-98	350	COG0077	Prephenate dehydratase	279
639000032	205	37.7	10	199	6	194	4.0e-25	108	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
639000033	320	38.43	18	287	1	264	2.0e-58	219	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
639000034	256	34.45	13	248	1	234	7.0e-44	170	COG1183	Phosphatidylserine synthase	234
639000035	273	28.52	1	268	25	289	1.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
639000038	494	37.97	20	362	2	338	7.0e-117	414	COG0059	Ketol-acid reductoisomerase	338
639000040	406	35.41	5	399	3	403	2.0e-69	256	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
639000041	163	55.28	1	161	3	163	6.0e-49	186	COG0440	Acetolactate synthase, small subunit	163
639000042	580	51.68	10	573	1	550	0.0e+00	684	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
639000043	858	54.6	5	858	1	784	0.0e+00	944	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
639000044	241	43.72	1	238	1	246	3.0e-55	208	COG1496	Copper oxidase (laccase) domain	249
639000045	328	45.7	9	307	1	289	2.0e-82	299	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
639000046	277	36.03	8	249	2	238	3.0e-40	159	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
639000047	219	29.91	1	211	4	217	6.0e-36	144	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
639000048	538	31.75	1	246	3	252	1.0e-39	158	COG0388	Predicted amidohydrolase	274
639000048	538	39.57	259	527	5	268	1.0e-66	247	COG0171	NH3-dependent NAD+ synthetase	268
639000049	531	25.95	178	497	96	425	1.0e-26	115	COG5002	Signal transduction histidine kinase	459
639000050	455	44.32	1	455	1	457	0.0e+00	511	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
639000051	167	42.52	1	122	2	128	4.0e-21	94.3	COG4968	Tfp pilus assembly protein PilE	139
639000053	207	27.4	5	206	10	192	7.0e-23	100	COG4726	Tfp pilus assembly protein PilX	196
639000056	186	27.21	2	137	5	135	5.0e-15	74.3	COG4970	Tfp pilus assembly protein FimT	181
639000057	315	64.86	1	296	2	294	2.0e-124	438	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
639000058	148	47.37	3	148	2	152	3.0e-38	151	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
639000059	829	47.02	1	823	114	933	0.0e+00	992	COG0060	Isoleucyl-tRNA synthetase	933
639000062	157	21.74	2	154	20	180	4.0e-10	57.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
639000063	237	33.03	13	229	10	227	3.0e-33	135	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
639000065	204	38.07	16	183	30	194	1.0e-27	116	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
639000069	677	24.68	420	649	2	227	8.0e-24	105	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
639000071	301	25.25	2	300	1	296	6.0e-27	115	COG0583	DNA-binding transcriptional regulator, LysR family	297
639000073	229	36	1	222	1	219	2.0e-36	145	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
639000075	192	25.73	1	177	2	202	2.0e-15	75.6	COG0406	Broad specificity phosphatase PhoE	208
639000076	299	27.27	8	243	15	253	5.0e-28	118	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
639000077	349	28.23	226	348	1	123	7.0e-16	78.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
639000079	201	34.5	1	200	3	200	1.0e-23	102	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
639000080	197	23.73	21	189	1	177	6.0e-11	61	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
639000081	190	19.89	15	190	21	192	5.0e-07	48.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
639000087	189	37.1	5	184	4	184	1.0e-38	152	COG3575	Uncharacterized protein	184
639000090	447	41.04	15	433	7	443	5.0e-111	394	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
639000091	284	35.27	15	284	8	281	9.0e-52	197	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
639000092	328	34.84	17	326	2	293	6.0e-52	198	COG1175	ABC-type sugar transport system, permease component	295
639000093	402	24.71	1	402	5	431	1.0e-25	111	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
639000096	216	25.35	4	211	11	214	4.0e-12	64.9	COG2755	Lysophospholipase L1 or related esterase	216
639000097	234	39.09	2	227	4	243	6.0e-34	137	COG0390	ABC-type iron transport system FetAB, permease component	256
639000099	1299	36.56	76	959	49	845	0.0e+00	696	COG1643	HrpA-like RNA helicase	845
639000100	551	34.84	14	535	3	526	7.0e-97	348	COG4615	ABC-type siderophore export system, fused ATPase and permease components	546
639000101	554	37.04	16	552	3	524	0.0e+00	463	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
639000102	267	43.02	1	256	1	250	9.0e-68	250	COG0121	Predicted glutamine amidotransferase	252
639000106	146	52.41	1	144	6	147	1.0e-41	162	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
639000107	97	41.86	8	93	15	100	3.0e-20	90	COG3100	Uncharacterized conserved protein YcgL, UPF0745 family	103
639000108	380	33.24	8	371	1	360	3.0e-75	275	COG0349	Ribonuclease D	361
639000109	203	40.91	1	198	1	198	2.0e-52	198	COG0353	Recombinational DNA repair protein RecR	198
639000110	108	52.83	1	105	2	105	3.0e-21	93.4	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
639000111	677	39.37	1	505	1	507	2.0e-129	456	COG2812	DNA polymerase III, gamma/tau subunits	515
639000112	323	35.9	8	159	3	156	3.0e-34	139	COG1683	Uncharacterized conserved protein YbbK, DUF523 family	156
639000113	465	38.59	1	459	2	460	2.0e-107	383	COG0415	Deoxyribodipyrimidine photolyase	461
639000114	433	41.38	3	433	8	436	6.0e-122	430	COG2907	Predicted NAD/FAD-binding protein	447
639000115	276	32.06	10	270	3	250	8.0e-49	187	COG3496	Uncharacterized conserved protein, DUF1365 family	261
639000116	410	44.1	114	401	1	283	7.0e-86	311	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
639000119	217	28.57	1	217	2	212	4.0e-35	141	COG0602	Organic radical activating enzyme	212
639000120	861	77.44	1	858	1	851	0.0e+00	1455	COG1049	Aconitase B	852
639000123	154	37.23	1	136	1	136	3.0e-25	107	COG1959	DNA-binding transcriptional regulator, IscR family	150
639000125	397	21.64	32	387	68	413	9.0e-22	98.1	COG2182	Maltose-binding periplasmic protein MalE	420
639000126	309	29.73	15	308	8	290	9.0e-36	144	COG1175	ABC-type sugar transport system, permease component	295
639000127	280	36.13	9	279	8	281	6.0e-51	194	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
639000128	148	32.54	10	133	7	131	1.0e-17	82.2	COG1917	Cupin domain protein related to quercetin dioxygenase	131
639000129	307	39.08	3	283	2	277	8.0e-81	294	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
639000130	486	43.33	1	475	4	459	2.0e-129	455	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
639000131	985	23.01	38	501	41	493	3.0e-42	167	COG0591	Na+/proline symporter	493
639000133	519	31.6	109	512	1	360	3.0e-62	233	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
639000136	442	37.85	61	440	2	391	2.0e-89	323	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
639000138	290	26.3	1	290	1	308	5.0e-24	105	COG0679	Predicted permease	311
639000139	136	61.22	22	118	10	107	4.0e-39	153	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
639000141	393	43.29	1	391	1	395	0.0e+00	463	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
639000144	202	30.95	34	199	11	177	8.0e-19	87.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
639000145	555	25.83	170	514	12	368	3.0e-26	113	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
639000146	180	23.7	2	173	1	161	9.0e-17	80	COG0262	Dihydrofolate reductase	167
639000147	504	48.69	1	303	2	297	8.0e-106	377	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
639000147	504	52.25	315	492	1	178	6.0e-64	238	COG1838	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain	184
639000148	246	37.6	1	246	4	253	8.0e-52	197	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
639000149	590	28.68	190	590	12	408	5.0e-31	129	COG0840	Methyl-accepting chemotaxis protein	408
639000151	517	44.12	1	451	1	449	0.0e+00	486	COG2925	Exonuclease I	475
639000156	116	31.4	31	116	3	87	7.0e-09	52.6	COG4453	Uncharacterized conserved protein, DUF1778 family	95
639000162	94	32.97	1	85	9	99	2.0e-10	57.7	COG2944	DNA-binding transcriptional regulator YiaG, XRE-type HTH domain	104
639000165	279	27.88	2	268	1	252	2.0e-27	116	COG1192	Cellulose biosynthesis protein BcsQ	259
639000185	713	40.88	1	548	1	561	0.0e+00	470	COG0550	DNA topoisomerase IA	570
639000189	325	30.94	23	317	22	292	2.0e-41	163	COG4974	Site-specific recombinase XerD	300
639000191	243	21.74	4	229	1	221	2.0e-21	96.3	COG0543	NAD(P)H-flavin reductase	252
639000192	248	22.36	1	245	3	239	2.0e-12	66.2	COG1378	Sugar-specific transcriptional regulator TrmB	247
639000193	220	30.89	1	179	6	193	1.0e-28	119	COG0300	Short-chain dehydrogenase	265
639000195	310	30.72	7	298	10	315	1.0e-34	140	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
639000196	99	28.87	1	97	10	104	2.0e-10	57.1	COG0640	DNA-binding transcriptional regulator, ArsR family	110
639000200	367	34.32	5	366	85	453	5.0e-83	301	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
639000201	253	37.15	1	252	2	239	5.0e-46	177	COG3279	DNA-binding response regulator, LytR/AlgR family	244
639000204	405	23.04	3	405	6	408	7.0e-45	175	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
639000205	239	40.18	4	221	2	220	5.0e-68	250	COG1136	ABC-type lipoprotein export system, ATPase component	226
639000209	109	50	1	104	2	105	2.0e-21	94	COG2076	Multidrug transporter EmrE and related cation transporters	106
639000212	624	38.31	44	598	1	522	0.0e+00	556	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
639000213	133	42.86	1	133	1	131	1.0e-38	151	COG0295	Cytidine deaminase	134
639000214	236	63.25	1	234	1	234	8.0e-95	339	COG0813	Purine-nucleoside phosphorylase	236
639000215	480	27.44	179	479	20	329	3.0e-32	133	COG0642	Signal transduction histidine kinase	336
639000216	266	45.02	33	261	1	228	1.0e-61	229	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
639000217	985	30.41	54	873	3	825	0.0e+00	569	COG3072	Adenylate cyclase	853
639000219	341	23.36	7	337	3	347	9.0e-42	164	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
639000220	1355	30.77	545	1207	2	708	2.0e-118	421	COG0643	Chemotaxis protein histidine kinase CheA	716
639000223	478	23.15	367	474	7	112	9.0e-11	61.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
639000225	306	24.12	4	306	1	297	6.0e-29	121	COG0583	DNA-binding transcriptional regulator, LysR family	297
639000227	695	56.63	3	692	6	695	0.0e+00	883	COG0480	Translation elongation factor EF-G, a GTPase	697
639000229	144	26.99	1	144	13	173	5.0e-09	53.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
639000230	222	31.25	28	218	23	214	1.0e-26	113	COG3235	Uncharacterized membrane protein	223
639000232	346	33.33	8	345	2	328	7.0e-52	197	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
639000233	534	40.35	13	505	1	490	3.0e-101	363	COG0366	Glycosidase	505
639000234	647	22.64	99	598	13	486	7.0e-41	162	COG0366	Glycosidase	505
639000235	382	37.18	148	380	53	281	3.0e-53	202	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
639000236	334	36.03	46	334	2	292	1.0e-46	180	COG1175	ABC-type sugar transport system, permease component	295
639000237	452	18.2	1	452	2	430	1.0e-19	91.2	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
639000241	526	70.21	1	526	2	528	0.0e+00	873	COG4108	Peptide chain release factor RF-3	528
639000245	533	38.31	4	533	19	554	4.0e-100	358	COG0747	ABC-type transport system, periplasmic component	556
639000246	257	71.66	8	254	7	253	3.0e-116	411	COG4598	ABC-type histidine transport system, ATPase component	256
639000247	254	30.86	1	252	1	267	1.0e-37	150	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
639000248	235	51.28	2	235	1	230	7.0e-68	250	COG4215	ABC-type arginine transport system, permease component	230
639000249	233	49.1	12	232	7	228	8.0e-66	243	COG4160	ABC-type arginine/histidine transport system, permease component	228
639000250	339	36.14	16	336	8	320	4.0e-68	251	COG2988	Succinylglutamate desuccinylase	324
639000251	353	40.11	1	349	2	337	2.0e-88	319	COG2008	Threonine aldolase	342
639000252	402	34.57	221	399	11	178	2.0e-33	137	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
639000253	445	35.94	1	445	1	448	2.0e-89	322	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
639000254	417	34.38	4	258	1	256	1.0e-61	230	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
639000255	348	44.02	7	346	2	333	5.0e-51	195	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
639000256	308	23.99	1	308	4	316	9.0e-29	121	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
639000257	178	28.19	30	174	39	183	2.0e-13	69.1	COG2096	Cob(I)alamin adenosyltransferase	184
639000259	213	43.39	27	213	5	190	5.0e-53	200	COG0302	GTP cyclohydrolase I	195
639000260	119	28.45	5	119	4	119	2.0e-20	91.4	COG1539	Dihydroneopterin aldolase	121
639000261	233	23.2	1	230	5	251	1.0e-21	97.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
639000263	251	28.63	2	247	1	248	7.0e-12	64.6	COG0730	Uncharacterized membrane protein YfcA	258
639000265	457	20.7	11	425	19	438	1.0e-11	64.8	COG0733	Na+-dependent transporter, SNF family	439
639000266	143	38.03	1	141	1	142	2.0e-28	118	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
639000267	124	47.92	26	121	3	96	5.0e-23	99	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
639000269	135	43.2	6	130	10	133	3.0e-32	130	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
639000270	161	27.05	18	138	2	123	7.0e-10	56.8	COG0526	Thiol-disulfide isomerase or thioredoxin	127
639000271	557	44.44	1	555	1	557	0.0e+00	535	COG0497	DNA repair ATPase RecN	557
639000272	200	41.45	1	190	1	193	6.0e-38	150	COG0576	Molecular chaperone GrpE (heat shock protein)	193
639000273	640	61.88	1	605	4	579	0.0e+00	667	COG0443	Molecular chaperone DnaK (HSP70)	579
639000274	374	66.04	1	371	1	369	0.0e+00	505	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
639000275	268	57.89	1	266	2	266	3.0e-91	328	COG0289	Dihydrodipicolinate reductase	266
639000276	337	38.16	25	321	38	334	8.0e-53	200	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
639000277	662	61.41	1	662	3	662	0.0e+00	1030	COG0021	Transketolase	663
639000281	282	54.65	1	267	1	269	6.0e-96	344	COG0266	Formamidopyrimidine-DNA glycosylase	273
639000282	681	53.19	1	681	1	689	0.0e+00	802	COG0751	Glycyl-tRNA synthetase, beta subunit	691
639000283	325	76.87	5	298	1	293	0.0e+00	538	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
639000285	482	43.55	1	482	1	488	2.0e-96	346	COG0168	Trk-type K+ transport system, membrane component	499
639000286	458	38.79	1	230	1	225	2.0e-43	170	COG0569	Trk K+ transport system, NAD-binding component	225
639000287	427	37.75	90	427	1	355	4.0e-79	288	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
639000288	314	51.16	3	303	2	302	9.0e-111	393	COG0223	Methionyl-tRNA formyltransferase	307
639000289	169	54.17	1	164	1	168	7.0e-56	209	COG0242	Peptide deformylase	168
639000291	368	38.29	1	362	1	346	4.0e-85	308	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
639000292	185	44.77	7	177	16	186	7.0e-47	180	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
639000293	306	64.55	7	304	6	303	2.0e-130	458	COG0408	Coproporphyrinogen III oxidase	303
639000294	301	28.48	7	162	16	166	4.0e-09	55.8	COG2203	GAF domain	175
639000295	123	32	36	110	2	75	1.0e-08	52.3	COG0695	Glutaredoxin	80
639000296	207	27.66	8	187	5	190	2.0e-22	99.6	COG3531	Predicted protein-disulfide isomerase , contains CxxC motif	212
639000298	261	31.43	1	260	1	278	6.0e-39	154	COG1355	Predicted class III extradiol dioxygenase, MEMO1 family	279
639000299	171	26.97	6	168	2	176	1.0e-15	76.1	COG1514	2'-5' RNA ligase	180
639000301	319	44.16	1	316	9	319	9.0e-41	161	COG0530	Ca2+/Na+ antiporter	320
639000302	173	33.33	1	169	4	176	1.0e-22	99.6	COG3038	Cytochrome b561	181
639000304	135	18.84	7	124	3	135	2.0e-07	48.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
639000308	481	33.92	45	481	1	438	8.0e-69	254	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
639000309	369	33.06	3	364	2	346	3.0e-77	282	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
639000310	757	35.09	39	752	1	694	0.0e+00	600	COG0209	Ribonucleotide reductase alpha subunit	696
639000311	216	31.84	1	216	11	233	2.0e-33	135	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
639000312	203	36.19	4	203	1	209	1.0e-39	156	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
639000313	367	25.42	15	355	10	363	5.0e-32	131	COG4585	Signal transduction histidine kinase	365
639000314	202	43.22	10	201	16	213	4.0e-48	184	COG3571	Predicted hydrolase of the alpha/beta-hydrolase fold	213
639000317	537	43.33	1	531	6	538	2.0e-119	423	COG2303	Choline dehydrogenase or related flavoprotein	542
639000319	64	35.48	2	63	1	62	1.0e-08	51.5	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
639000321	376	68.73	1	371	5	375	0.0e+00	582	COG5008	Tfp pilus assembly protein, ATPase PilU	375
639000322	344	66.47	1	342	3	345	0.0e+00	549	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
639000323	235	50.88	5	230	2	228	4.0e-75	274	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
639000324	273	37.69	4	269	3	266	1.0e-60	227	COG0345	Pyrroline-5-carboxylate reductase	266
639000326	381	49.47	1	375	1	367	1.0e-127	449	COG2021	Homoserine acetyltransferase	368
639000329	124	27.97	2	119	13	115	8.0e-12	62.6	COG2149	Uncharacterized membrane protein YidH, DUF202 family	120
639000330	202	46.97	5	201	2	193	4.0e-65	240	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
639000331	387	40.72	9	387	34	413	1.0e-107	383	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
639000332	454	43.23	6	422	1	419	1.0e-121	430	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
639000335	187	35.81	31	178	3	149	2.0e-21	96.1	COG3154	Predicted lipid carrier protein YhbT, SCP2 domain	168
639000336	331	35.12	1	331	7	312	4.0e-76	278	COG0826	Collagenase-like protease, PrtC family	347
639000337	294	20.67	2	292	1	293	2.0e-38	153	COG0826	Collagenase-like protease, PrtC family	347
639000340	222	40	22	222	17	217	2.0e-36	145	COG0850	Septum formation inhibitor MinC	219
639000341	269	65.56	1	269	1	269	6.0e-117	413	COG2894	Septum formation inhibitor-activating ATPase MinD	272
639000342	84	46.34	3	84	2	82	2.0e-20	90.7	COG0851	Septum formation topological specificity factor MinE	88
639000343	315	52.08	3	313	1	301	7.0e-94	337	COG0492	Thioredoxin reductase	305
639000344	267	22.09	25	266	27	279	1.0e-10	60.3	COG3725	Membrane protein required for beta-lactamase induction	282
639000345	287	49.64	11	284	1	278	1.0e-83	303	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
639000346	285	22.76	1	285	3	286	8.0e-20	91.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
639000347	347	16.2	40	347	67	374	6.0e-08	51.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
639000354	178	31.16	32	163	1	138	2.0e-13	68.9	COG4968	Tfp pilus assembly protein PilE	139
639000355	563	48.2	64	561	6	498	0.0e+00	567	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
639000356	407	40.7	10	407	3	396	5.0e-105	374	COG1459	Type II secretory pathway, component PulF	397
639000357	291	37.59	16	288	6	251	2.0e-33	136	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
639000358	200	41.62	1	196	3	199	3.0e-51	195	COG0237	Dephospho-CoA kinase	201
639000359	66	45.45	5	59	10	64	5.0e-12	62.8	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
639000360	407	45.71	13	407	14	404	1.0e-124	440	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
639000361	907	56.25	5	900	4	822	0.0e+00	1054	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
639000362	306	34.43	97	306	56	267	6.0e-32	131	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
639000363	258	60.94	1	255	49	300	2.0e-102	365	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
639000365	156	32.7	1	154	1	159	1.0e-33	135	COG3160	Regulator of sigma D	162
639000368	503	45.07	8	500	22	517	0.0e+00	502	COG2918	Gamma-glutamylcysteine synthetase	518
639000371	701	43.87	31	681	2	653	0.0e+00	578	COG0210	Superfamily I DNA or RNA helicase	655
639000375	381	26.48	69	378	66	378	2.0e-26	113	COG3853	Uncharacterized conserved protein YaaN involved in tellurite resistance	386
639000376	207	23.87	9	206	18	238	2.0e-12	65.7	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
639000377	338	33.45	26	307	14	276	5.0e-49	188	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
639000379	151	45.03	1	150	5	154	1.0e-30	125	COG1522	DNA-binding transcriptional regulator, Lrp family	154
639000381	205	27.65	9	165	4	163	2.0e-16	79.3	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
639000383	114	31.68	14	109	1	101	1.0e-09	55.2	COG1695	DNA-binding transcriptional regulator, PadR family	138
639000384	309	35.35	1	98	10	108	1.0e-08	54	COG0640	DNA-binding transcriptional regulator, ArsR family	110
639000386	391	37.11	18	390	5	392	7.0e-82	297	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
639000387	314	55.06	1	314	3	312	4.0e-118	417	COG0435	Glutathionyl-hydroquinone reductase	324
639000388	154	45.19	13	146	11	140	9.0e-14	69.6	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
639000389	302	33	3	299	2	297	2.0e-45	176	COG0583	DNA-binding transcriptional regulator, LysR family	297
639000390	158	28.44	39	147	13	121	2.0e-10	58.4	COG4270	Uncharacterized membrane protein	131
639000391	284	23.18	2	217	1	218	3.0e-17	82.7	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
639000394	252	34.12	1	251	3	251	1.0e-36	146	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
639000395	297	33.87	171	294	1	124	1.0e-20	94.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
639000401	300	28.96	1	293	1	297	3.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
639000402	209	33.06	11	128	7	121	6.0e-10	57.7	COG2863	Cytochrome c553	121
639000403	391	32.31	4	371	5	359	5.0e-61	228	COG1858	Cytochrome c peroxidase	364
639000405	253	18.85	1	253	5	260	8.0e-13	67.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
639000408	294	41.22	40	292	39	300	9.0e-44	170	COG0668	Small-conductance mechanosensitive channel	316
639000411	306	16.54	1	266	3	267	2.0e-17	83.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
639000413	230	49.55	4	226	1	224	8.0e-75	273	COG1136	ABC-type lipoprotein export system, ATPase component	226
639000414	409	24.15	1	405	3	405	3.0e-37	149	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
639000415	407	23.21	1	406	6	407	4.0e-37	149	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
639000418	507	33.85	5	506	15	517	2.0e-75	276	COG0815	Apolipoprotein N-acyltransferase	518
639000419	253	40.4	1	250	4	250	8.0e-74	270	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
639000420	234	46.84	1	234	1	237	6.0e-79	287	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
639000421	332	29.88	4	331	2	294	6.0e-38	151	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
639000422	423	34.11	160	417	80	308	6.0e-26	112	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
639000429	423	25.65	23	272	1	264	1.0e-25	111	COG0548	Acetylglutamate kinase	265
639000429	423	45.99	280	415	4	140	3.0e-35	143	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
639000430	463	35.17	18	451	1	413	5.0e-104	371	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
639000431	216	33.17	6	209	11	214	7.0e-37	147	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
639000432	140	43.8	1	137	2	136	6.0e-28	116	COG1765	Uncharacterized OsmC-related protein	137
639000433	498	34.62	8	334	1	337	7.0e-53	201	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
639000434	583	41.82	89	580	14	500	0.0e+00	506	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
639000435	406	57.84	1	406	1	403	0.0e+00	579	COG0137	Argininosuccinate synthase	403
639000437	261	30.38	21	255	5	223	4.0e-19	88.7	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
639000438	773	33.97	323	633	34	336	7.0e-46	179	COG0642	Signal transduction histidine kinase	336
639000438	773	36.44	650	764	6	123	7.0e-20	93	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
639000439	426	22.42	39	421	47	417	4.0e-09	56.4	COG2223	Nitrate/nitrite transporter NarK	417
639000443	479	26.1	3	467	4	446	2.0e-61	229	COG0527	Aspartokinase	447
639000445	290	23.84	9	289	16	290	1.0e-12	67.2	COG5006	Threonine/homoserine efflux transporter RhtA	292
639000446	334	21.83	1	334	3	335	4.0e-36	145	COG3081	Nucleoid-associated protein YejK (function unknown)	335
639000447	294	46.1	1	294	2	290	2.0e-71	262	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
639000448	398	61.62	1	396	1	386	0.0e+00	507	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
639000449	357	57.75	59	342	6	289	4.0e-97	348	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
639000450	328	27.22	1	326	4	300	8.0e-48	184	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
639000452	312	26.16	14	309	2	294	1.0e-21	97.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
639000454	327	41.41	1	324	9	333	3.0e-89	321	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
639000456	116	54.55	1	116	5	125	6.0e-28	116	COG0256	Ribosomal protein L18	125
639000457	177	54.8	1	176	1	176	2.0e-57	215	COG0097	Ribosomal protein L6P/L9E	178
639000458	130	56.82	1	130	1	132	3.0e-45	173	COG0096	Ribosomal protein S8	132
639000459	101	48.33	42	101	2	61	8.0e-17	78.7	COG0199	Ribosomal protein S14	61
639000460	179	67.04	1	179	1	179	5.0e-77	280	COG0094	Ribosomal protein L5	180
639000461	108	54.13	1	107	2	104	3.0e-14	70.3	COG0198	Ribosomal protein L24	104
639000462	122	72.95	1	122	1	122	3.0e-48	183	COG0093	Ribosomal protein L14	122
639000463	86	55.7	7	85	9	87	2.0e-22	97.6	COG0186	Ribosomal protein S17	87
639000464	63	50	2	63	4	65	2.0e-11	60.7	COG0255	Ribosomal protein L29	69
639000465	137	62.04	1	135	2	138	6.0e-46	176	COG0197	Ribosomal protein L16/L10AE	146
639000467	228	59.63	12	228	1	218	4.0e-75	274	COG0092	Ribosomal protein S3	233
639000468	111	63.96	1	111	9	119	5.0e-35	139	COG0091	Ribosomal protein L22	120
639000469	91	72.83	1	91	1	92	2.0e-37	147	COG0185	Ribosomal protein S19	93
639000470	274	63.64	1	274	1	275	3.0e-108	384	COG0090	Ribosomal protein L2	275
639000471	98	56.04	7	96	2	92	4.0e-22	96	COG0089	Ribosomal protein L23	94
639000472	201	46	7	201	12	211	6.0e-52	196	COG0088	Ribosomal protein L4	214
639000473	210	57.82	2	209	1	211	9.0e-76	276	COG0087	Ribosomal protein L3	218
639000474	103	69.61	1	102	1	102	8.0e-37	144	COG0051	Ribosomal protein S10	104
639000477	376	46.47	21	376	9	374	9.0e-78	284	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
639000478	617	33.17	8	612	5	592	2.0e-124	439	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
639000479	155	45.16	1	155	1	155	9.0e-54	202	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
639000480	121	47.06	13	114	4	105	1.0e-26	111	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
639000481	214	30.88	12	210	7	195	1.0e-26	113	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
639000482	412	58.35	1	411	5	417	0.0e+00	588	COG0014	Gamma-glutamyl phosphate reductase	417
639000483	426	30.48	7	191	12	198	4.0e-21	96.1	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
639000485	151	60.26	1	151	1	151	2.0e-54	204	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
639000486	366	41.78	149	358	1	211	9.0e-50	190	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
639000486	366	71.23	3	148	1	146	2.0e-60	226	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
639000487	373	35.58	216	372	10	169	6.0e-25	108	COG0807	GTP cyclohydrolase II	193
639000487	373	63.37	6	207	3	203	8.0e-83	300	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
639000488	158	61.18	1	152	1	152	3.0e-51	194	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
639000489	151	44.9	5	144	4	150	1.0e-31	129	COG0781	Transcription termination factor NusB	151
639000490	334	54.98	6	316	1	309	4.0e-121	428	COG4608	ABC-type oligopeptide transport system, ATPase component	309
639000491	325	58.81	3	318	1	315	1.0e-127	449	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
639000492	296	50.17	7	296	3	288	1.0e-75	276	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
639000497	235	24.21	19	232	1	250	1.0e-19	90.3	COG1192	Cellulose biosynthesis protein BcsQ	259
639000500	195	32.47	1	194	2	167	6.0e-31	127	COG0723	Rieske Fe-S protein	177
639000501	416	48.07	11	398	8	372	2.0e-83	303	COG1290	Cytochrome b subunit of the bc complex	381
639000503	282	44.94	1	261	1	266	6.0e-76	277	COG0196	FAD synthase	304
639000504	506	47.73	1	504	10	515	7.0e-104	371	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
639000505	649	44.17	247	527	2	284	4.0e-86	312	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
639000509	254	31.85	6	252	69	305	9.0e-43	167	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
639000512	326	47.37	1	315	114	432	5.0e-87	314	COG0201	Preprotein translocase subunit SecY	436
