gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
649928203	465	45.51	5	461	1	408	7.0e-121	427	COG0593	Chromosomal replication initiation ATPase DnaA	408
649928204	372	37.27	1	372	1	364	1.0e-69	257	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
649928205	364	38.9	1	362	1	361	2.0e-83	302	COG1195	Recombinational DNA repair ATPase RecF	363
649928206	796	63.65	5	564	2	562	0.0e+00	876	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
649928207	837	60.84	8	810	9	804	0.0e+00	1029	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
649928209	335	56.97	4	333	3	329	3.0e-119	421	COG0240	Glycerol-3-phosphate dehydrogenase	329
649928210	762	27.86	278	753	6	453	9.0e-58	219	COG5002	Signal transduction histidine kinase	459
649928211	510	24.83	63	510	45	455	2.0e-40	160	COG5002	Signal transduction histidine kinase	459
649928214	308	43	1	304	1	293	3.0e-76	278	COG1131	ABC-type multidrug transport system, ATPase component	293
649928215	251	23.43	13	248	45	282	7.0e-08	51.1	COG0842	ABC-type multidrug transport system, permease component	286
649928216	357	34.09	1	349	12	344	5.0e-55	208	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649928217	339	55.78	1	339	6	351	2.0e-115	408	COG0407	Uroporphyrinogen-III decarboxylase	352
649928218	317	31.74	29	317	33	322	4.0e-53	202	COG0598	Mg2+ and Co2+ transporter CorA	322
649928219	407	20.89	3	406	6	440	6.0e-24	105	COG2067	Long-chain fatty acid transport protein	440
649928220	96	54.55	1	77	3	79	2.0e-21	93.8	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
649928221	469	42.92	25	467	1	450	3.0e-120	425	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
649928222	282	33.72	1	251	9	252	8.0e-39	154	COG0543	NAD(P)H-flavin reductase	252
649928223	291	19.86	1	291	12	286	1.0e-05	44.5	COG5006	Threonine/homoserine efflux transporter RhtA	292
649928224	280	29.3	4	274	1	251	6.0e-41	161	COG0543	NAD(P)H-flavin reductase	252
649928227	161	53.91	6	133	1	128	2.0e-47	181	COG1908	Coenzyme F420-reducing hydrogenase, delta subunit	132
649928228	665	50	3	665	2	621	0.0e+00	672	COG1148	Heterodisulfide reductase, subunit A (polyferredoxin)	622
649928229	317	34.42	8	311	1	287	1.0e-55	210	COG2048	Heterodisulfide reductase, subunit B	293
649928231	569	37.46	7	563	15	567	5.0e-117	415	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
649928232	601	38.97	18	601	1	567	2.0e-127	449	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
649928233	636	37.1	4	472	1	442	3.0e-89	323	COG3276	Selenocysteine-specific translation elongation factor	447
649928237	318	44.3	1	313	2	315	3.0e-94	338	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
649928238	518	32.58	31	383	59	408	1.0e-44	174	COG0840	Methyl-accepting chemotaxis protein	408
649928240	284	22.33	5	203	1	190	1.0e-13	70.4	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
649928241	539	47.23	24	537	10	531	0.0e+00	479	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
649928242	199	31.12	3	198	23	206	1.0e-28	119	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
649928244	296	34.01	12	203	35	230	2.0e-46	179	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
649928246	398	43.59	2	389	1	388	2.0e-118	418	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
649928247	347	32.01	5	344	1	350	4.0e-68	251	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
649928249	232	35.41	5	209	3	207	5.0e-34	138	COG2085	Predicted dinucleotide-binding enzyme	211
649928253	97	60.44	6	96	8	96	4.0e-23	99.6	COG3636	DNA-binding prophage protein	100
649928254	96	62.5	1	96	3	98	7.0e-32	128	COG3657	Putative component of the toxin-antitoxin plasmid stabilization module	100
649928267	772	34.62	3	772	2	764	0.0e+00	557	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
649928268	77	31.43	3	72	8	77	2.0e-06	44.5	COG3062	Cytoplasmic chaperone NapD for the signal peptide of periplasmic nitrate reductase NapAB	94
649928270	278	22.22	1	268	2	289	4.0e-29	121	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
649928271	465	27.85	16	458	1	431	7.0e-46	178	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
649928276	356	41.31	6	353	1	348	6.0e-79	287	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
649928277	754	29.94	2	619	152	712	4.0e-99	356	COG0643	Chemotaxis protein histidine kinase CheA	716
649928278	483	25.57	136	483	59	403	5.0e-26	112	COG0840	Methyl-accepting chemotaxis protein	408
649928279	346	29.94	185	341	2	158	9.0e-23	101	COG0835	Chemotaxis signal transduction protein	165
649928280	474	36.86	4	274	4	268	3.0e-61	229	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
649928281	138	37.14	1	69	1	70	3.0e-10	57.7	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
649928283	701	27.92	194	444	52	308	6.0e-21	96.4	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649928284	385	46.27	5	383	1	388	5.0e-114	404	COG1168	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	388
649928285	158	28.4	75	155	32	110	1.0e-07	49.5	COG1416	Intracellular sulfur oxidation protein, DsrE/DsrF family	112
649928286	347	24.64	141	347	2	168	6.0e-27	114	COG0516	IMP dehydrogenase/GMP reductase	170
649928287	418	22.34	3	378	20	411	2.0e-23	103	COG2271	Sugar phosphate permease	448
649928288	340	34.55	27	295	9	280	1.0e-45	177	COG0042	tRNA-dihydrouridine synthase	323
649928289	169	38.46	1	169	1	141	1.0e-27	115	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
649928292	214	47.89	1	208	1	210	8.0e-51	193	COG3132	Uncharacterized conserved protein YceH, UPF0502 family	215
649928293	100	39.58	1	96	1	96	1.0e-18	85.1	COG5626	Uncharacterized protein	97
649928294	240	40.5	36	235	13	191	8.0e-42	163	COG4887	Uncharacterized metal-binding protein conserved in archaea	191
649928296	660	18.16	25	494	3	465	1.0e-17	85.2	COG0531	Amino acid transporter	466
649928298	234	42.36	11	234	1	228	4.0e-55	208	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649928300	182	37.64	3	176	2	177	2.0e-29	122	COG1514	2'-5' RNA ligase	180
649928301	422	61.5	1	421	1	425	0.0e+00	581	COG0172	Seryl-tRNA synthetase	429
649928309	684	22.54	54	684	27	608	2.0e-41	164	COG4206	Outer membrane cobalamin receptor protein	608
649928312	748	40.27	237	747	5	498	1.0e-124	441	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649928313	289	30.68	4	267	19	269	7.0e-65	240	COG2326	Polyphosphate kinase 2, PPK2 family	270
649928314	892	40.96	599	889	5	295	1.0e-68	255	COG3285	Eukaryotic-type DNA primase	299
649928316	146	14.29	6	139	25	164	3.0e-03	34.6	COG1633	Rubrerythrin	176
649928317	628	31.5	10	575	26	608	5.0e-122	432	COG0296	1,4-alpha-glucan branching enzyme	628
649928319	986	41.76	10	983	2	886	0.0e+00	829	COG3280	Maltooligosyltrehalose synthase	889
649928321	1114	33.08	15	505	1	492	1.0e-90	328	COG0366	Glycosidase	505
649928323	258	41.98	1	258	3	264	3.0e-66	245	COG1273	Non-homologous end joining protein Ku, dsDNA break repair	278
649928327	127	30.83	1	120	3	113	8.0e-13	66	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
649928328	282	24.66	3	221	5	225	1.0e-25	110	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
649928329	632	38.06	98	612	5	496	1.0e-113	404	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649928332	662	68.55	1	654	2	656	0.0e+00	1077	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
649928333	471	33.85	16	460	1	412	6.0e-75	275	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
649928336	201	54.92	6	197	4	194	5.0e-69	253	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
649928339	829	27.71	30	526	1	478	6.0e-49	189	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649928340	496	46.77	2	494	1	481	3.0e-126	445	COG1530	Ribonuclease G or E	487
649928341	392	64.87	1	389	3	392	0.0e+00	581	COG0027	Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	394
649928342	101	42.57	1	100	5	105	5.0e-16	76.2	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
649928343	102	57.28	1	102	1	103	4.0e-28	116	COG0261	Ribosomal protein L21	103
649928344	85	71.76	1	85	1	85	7.0e-32	128	COG0211	Ribosomal protein L27	87
649928345	338	58.28	1	336	1	338	0.0e+00	468	COG0536	GTPase involved in cell partioning and DNA repair	369
649928347	463	39.15	2	462	2	471	7.0e-74	271	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
649928348	496	50.61	4	495	2	485	2.0e-130	459	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
649928349	625	39.65	6	619	1	606	3.0e-107	383	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
649928350	102	43	3	102	2	100	3.0e-16	76.7	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
649928351	161	31.1	1	161	3	165	2.0e-13	68.7	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
649928352	176	39.86	8	149	13	150	5.0e-33	133	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
649928354	329	54.38	5	328	8	329	2.0e-88	319	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
649928355	644	31.86	1	555	1	579	1.0e-108	387	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
649928356	420	50.48	4	416	12	424	0.0e+00	525	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
649928357	160	39.07	1	151	4	154	7.0e-36	143	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
649928358	794	56.68	1	186	9	194	5.0e-66	246	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
649928358	794	57.22	407	794	11	398	0.0e+00	552	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
649928359	134	40.17	9	125	7	123	3.0e-20	91	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
649928364	158	52.9	1	155	3	156	7.0e-48	183	COG1225	Peroxiredoxin	157
649928366	399	20.49	6	397	3	444	8.0e-28	118	COG1232	Protoporphyrinogen oxidase	444
649928368	319	24.12	1	307	1	295	2.0e-13	70.5	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
649928369	308	26.57	16	289	28	313	5.0e-14	72.1	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
649928370	1157	47.18	10	1156	1	1133	0.0e+00	1205	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
649928374	575	42.89	1	475	1	474	8.0e-129	454	COG2812	DNA polymerase III, gamma/tau subunits	515
649928375	104	47.06	3	104	5	105	5.0e-18	82.6	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
649928376	197	56.57	2	197	1	198	3.0e-70	257	COG0353	Recombinational DNA repair protein RecR	198
649928377	1182	37.66	3	385	1	357	3.0e-88	321	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
649928378	66	61.19	1	66	1	67	2.0e-21	93.7	COG1278	Cold shock protein, CspA family	67
649928380	945	68.18	1	945	1	934	0.0e+00	1554	COG0178	Excinuclease UvrABC ATPase subunit	935
649928383	328	34.94	6	327	6	330	1.0e-55	210	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
649928385	447	26.11	242	437	1	178	2.0e-13	70.5	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649928386	168	34.91	1	167	2	169	8.0e-30	123	COG0703	Shikimate kinase	172
649928397	220	45.5	1	217	1	213	3.0e-42	165	COG3132	Uncharacterized conserved protein YceH, UPF0502 family	215
649928398	356	45.85	6	353	5	352	6.0e-106	377	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
649928400	268	27.7	1	256	1	278	4.0e-13	68.8	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
649928401	829	42.26	21	824	5	774	0.0e+00	789	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
649928402	94	60.22	1	93	2	94	4.0e-24	102	COG0776	Bacterial nucleoid DNA-binding protein	94
649928403	442	43.62	1	424	29	457	4.0e-118	418	COG0513	Superfamily II DNA and RNA helicase	513
649928404	395	40.83	4	390	4	388	2.0e-111	395	COG0426	Flavorubredoxin	388
649928405	752	45.73	8	751	3	730	0.0e+00	753	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
649928406	616	22.16	344	528	9	170	4.0e-04	40.6	COG2864	Cytochrome b subunit of formate dehydrogenase	218
649928409	457	56.46	2	457	1	457	0.0e+00	616	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
649928410	609	51.8	1	609	1	597	0.0e+00	794	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
649928412	252	31.71	131	252	1	123	7.0e-23	101	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649928413	100	30.77	35	86	7	57	4.0e-03	33.3	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
649928415	101	51.16	1	86	2	87	9.0e-24	101	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
649928416	93	41.49	1	93	1	94	2.0e-22	97.3	COG3549	Plasmid maintenance system killer protein	94
649928418	104	50	1	104	1	106	2.0e-27	113	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
649928419	147	34.44	60	147	20	107	2.0e-10	58.7	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
649928421	172	38.1	3	165	2	166	7.0e-26	110	COG0717	Deoxycytidine triphosphate deaminase	183
649928422	584	39.53	164	420	82	327	1.0e-44	174	COG0642	Signal transduction histidine kinase	336
649928423	225	31.3	1	113	4	116	4.0e-15	74.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
649928424	730	45.81	7	635	3	644	0.0e+00	608	COG0210	Superfamily I DNA or RNA helicase	655
649928426	334	50.45	1	334	1	332	5.0e-101	361	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
649928428	357	42.22	1	357	9	360	9.0e-82	297	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
649928429	815	48.07	622	801	2	181	7.0e-46	179	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649928430	334	22.32	1	305	2	338	6.0e-27	115	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
649928431	551	22.31	64	544	2	493	2.0e-33	137	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649928432	357	56.32	4	351	5	352	0.0e+00	466	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
649928433	389	31.87	9	387	6	388	2.0e-68	253	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
649928434	279	26.55	13	276	9	280	6.0e-28	118	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649928435	807	31.36	403	807	7	408	7.0e-42	166	COG0840	Methyl-accepting chemotaxis protein	408
649928439	272	26.13	161	270	12	122	6.0e-16	78.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649928440	209	25.96	5	209	3	206	1.0e-20	93.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
649928450	118	30.97	9	118	3	114	8.0e-12	62.2	COG4679	Phage-related protein	116
649928456	402	30.16	147	389	45	291	4.0e-26	112	COG4974	Site-specific recombinase XerD	300
649928464	166	30.72	11	166	13	176	5.0e-15	74	COG4719	Uncharacterized protein	176
649928466	448	39.33	1	448	1	476	9.0e-107	380	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
649928467	289	33.45	1	284	4	289	5.0e-35	141	COG0382	4-hydroxybenzoate polyprenyltransferase	289
649928468	203	47.52	2	203	1	190	3.0e-63	234	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
649928469	358	47.37	1	358	6	366	3.0e-110	391	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
649928470	354	45.28	1	354	7	366	5.0e-105	374	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
649928471	350	39.32	4	346	2	351	6.0e-81	294	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
649928472	377	35.62	16	377	1	360	2.0e-60	226	COG0349	Ribonuclease D	361
649928473	234	37.14	1	229	1	244	4.0e-45	174	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
649928475	246	41.87	1	244	3	246	2.0e-51	195	COG1385	16S rRNA U1498 N3-methylase RsmE	246
649928476	306	39.03	4	305	3	300	1.0e-68	253	COG2264	Ribosomal protein L11 methylase PrmA	300
649928477	270	39.93	3	268	5	271	8.0e-69	254	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
649928478	224	50	1	224	1	229	9.0e-65	239	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649928479	458	46.84	11	353	13	341	3.0e-79	289	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649928480	335	24.86	1	334	2	279	3.0e-31	129	COG1234	Ribonuclease BN, tRNA processing enzyme	292
649928484	96	64.58	1	96	1	96	8.0e-32	128	COG0234	Co-chaperonin GroES (HSP10)	96
649928485	547	50.09	1	535	1	524	0.0e+00	502	COG0459	Chaperonin GroEL (HSP60 family)	524
649928487	479	27.74	148	435	59	344	1.0e-38	154	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
649928489	683	20.17	7	676	20	642	5.0e-23	103	COG2766	Predicted Ser/Thr protein kinase	649
649928490	453	26.41	79	377	22	348	1.0e-24	107	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
649928491	540	23.34	19	500	26	474	5.0e-36	146	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
649928492	762	17.98	7	651	3	561	3.0e-09	57.6	COG2766	Predicted Ser/Thr protein kinase	649
649928493	394	32.88	28	392	47	408	4.0e-47	182	COG0840	Methyl-accepting chemotaxis protein	408
649928494	296	63.82	1	292	1	293	9.0e-116	409	COG0074	Succinyl-CoA synthetase, alpha subunit	293
649928495	385	57.81	1	381	1	381	0.0e+00	502	COG0045	Succinyl-CoA synthetase, beta subunit	387
649928498	171	53.08	43	171	1	130	2.0e-54	204	COG0229	Peptide methionine sulfoxide reductase MsrB	140
649928499	201	52.6	22	193	2	174	1.0e-64	239	COG0225	Peptide methionine sulfoxide reductase MsrA	174
649928500	576	44.31	1	322	3	326	9.0e-81	294	COG1796	DNA polymerase/3'-5' exonuclease PolX	326
649928501	156	58.33	1	155	1	153	1.0e-50	192	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
649928502	354	41.36	32	354	3	322	6.0e-73	267	COG0598	Mg2+ and Co2+ transporter CorA	322
649928503	390	51.17	7	381	3	387	2.0e-101	362	COG3004	Na+/H+ antiporter NhaA	390
649928504	880	37.37	1	874	4	858	0.0e+00	647	COG0308	Aminopeptidase N	859
649928505	304	47.37	192	266	2	76	6.0e-17	81.6	COG4892	Predicted heme/steroid binding protein	81
649928506	408	41.3	225	407	2	178	2.0e-35	143	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649928508	799	45.13	239	741	5	500	0.0e+00	508	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649928511	527	32.2	11	358	16	340	1.0e-47	184	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
649928515	429	30.43	7	429	44	479	8.0e-57	214	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
649928517	1148	60.84	5	1148	6	1148	0.0e+00	1717	COG1038	Pyruvate carboxylase	1149
649928518	228	43.61	2	228	1	226	2.0e-44	172	COG1811	Uncharacterized membrane protein YqgA, affects biofilm formation	228
649928519	279	51.69	1	266	3	268	4.0e-86	311	COG0796	Glutamate racemase	269
649928523	274	58.51	1	241	3	243	3.0e-94	338	COG3959	Transketolase, N-terminal subunit	243
649928524	310	62.54	1	306	6	312	1.0e-116	413	COG3958	Transketolase, C-terminal subunit	312
649928526	493	27.67	142	481	15	336	3.0e-38	153	COG0642	Signal transduction histidine kinase	336
649928527	456	50	1	453	2	455	0.0e+00	505	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649928529	368	48.23	3	368	2	354	3.0e-102	365	COG2768	Uncharacterized Fe-S center protein	354
649928531	402	45.76	10	396	3	375	3.0e-95	342	COG3328	Transposase (or an inactivated derivative)	379
649928533	153	34.4	15	139	1	125	1.0e-12	66.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
649928534	596	28.71	6	590	18	606	1.0e-73	271	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
649928535	255	28.15	1	244	3	265	4.0e-31	128	COG0289	Dihydrodipicolinate reductase	266
649928536	752	37.6	255	743	1	485	4.0e-129	455	COG0380	Trehalose-6-phosphate synthase	486
649928537	262	29.92	3	228	1	235	2.0e-22	100	COG1877	Trehalose-6-phosphatase	266
649928540	198	36.14	33	197	23	188	1.0e-27	116	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
649928542	766	42.09	261	764	15	498	1.0e-124	440	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649928543	655	23.93	10	408	16	399	3.0e-34	140	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
649928551	120	42.45	11	116	2	107	6.0e-33	132	COG1733	DNA-binding transcriptional regulator, HxlR family	120
649928552	211	34.34	1	187	1	195	1.0e-37	149	COG0655	Multimeric flavodoxin WrbA	207
649928554	1126	32.35	602	1126	4	530	1.0e-82	302	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
649928557	154	28.4	45	125	26	103	3.0e-10	57.7	COG2944	DNA-binding transcriptional regulator YiaG, XRE-type HTH domain	104
649928560	315	38.58	1	315	1	321	2.0e-70	259	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
649928561	266	24.55	157	266	44	151	7.0e-05	41.5	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649928563	614	27.97	21	578	11	570	6.0e-72	265	COG2414	Aldehyde:ferredoxin oxidoreductase	614
649928564	74	26.19	2	74	1	84	2.0e-04	37.2	COG1977	Molybdopterin converting factor, small subunit	84
649928565	236	54.66	1	235	1	236	5.0e-90	323	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
649928566	241	50.8	2	238	1	250	5.0e-81	293	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
649928567	334	38.22	4	307	2	313	8.0e-44	171	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
649928568	294	34.01	1	292	3	292	8.0e-35	141	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
649928569	413	27.12	30	378	12	349	3.0e-37	149	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
649928570	591	38.73	25	590	3	559	5.0e-122	432	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
649928571	436	50.7	5	432	18	446	0.0e+00	539	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
649928572	870	37.11	474	728	94	336	3.0e-42	167	COG0642	Signal transduction histidine kinase	336
649928573	169	32.67	19	167	40	188	1.0e-24	105	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
649928574	246	38.59	7	239	8	246	3.0e-49	188	COG0631	Serine/threonine protein phosphatase PrpC	262
649928576	248	31.88	6	233	10	238	3.0e-39	155	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
649928577	103	31.31	5	103	3	100	9.0e-06	41.8	COG4541	Uncharacterized membrane protein	100
649928579	311	21.78	23	242	34	234	4.0e-10	59.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
649928580	149	32.81	1	127	1	128	2.0e-16	78.5	COG1959	DNA-binding transcriptional regulator, IscR family	150
649928581	153	23.84	4	148	1	145	5.0e-07	47.6	COG1247	L-amino acid N-acyltransferase YncA	169
649928582	652	38.63	127	649	9	546	4.0e-116	412	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
649928583	526	46.09	14	522	4	501	0.0e+00	500	COG0427	Acyl-CoA hydrolase	501
649928584	162	31.54	4	132	6	133	1.0e-18	85.7	COG0824	Acyl-CoA thioesterase FadM	137
649928585	357	34.43	221	342	30	151	6.0e-17	81.9	COG1607	Acyl-CoA hydrolase	157
649928586	661	27.46	282	659	1	385	6.0e-58	219	COG0247	Fe-S oxidoreductase	388
649928587	258	36.26	1	257	1	260	1.0e-52	199	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
649928588	302	38.26	1	302	1	311	4.0e-64	238	COG2025	Electron transfer flavoprotein, alpha subunit	313
649928590	396	24.94	11	393	8	388	1.0e-23	104	COG0183	Acetyl-CoA acetyltransferase	392
649928591	260	43.46	1	257	2	257	2.0e-51	195	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
649928592	289	47.72	5	288	2	286	1.0e-93	336	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
649928593	582	43.03	25	421	4	392	6.0e-81	295	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
649928594	107	25.84	15	102	13	101	2.0e-08	50.6	COG3162	Uncharacterized membrane protein, DUF485 family	102
649928595	615	38.64	35	606	8	528	2.0e-104	373	COG4147	Na+(or H+)/acetate symporter ActP	529
649928596	418	20.05	25	406	31	415	1.0e-06	48.3	COG2223	Nitrate/nitrite transporter NarK	417
649928597	428	33.81	16	427	2	396	3.0e-77	282	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
649928599	270	43.33	1	268	2	259	2.0e-60	225	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
649928600	447	47.85	107	432	1	312	1.0e-96	346	COG2025	Electron transfer flavoprotein, alpha subunit	313
649928601	658	27.94	266	658	1	386	5.0e-61	229	COG0247	Fe-S oxidoreductase	388
649928602	357	21.66	5	340	3	297	6.0e-18	85.4	COG1397	ADP-ribosylglycohydrolase	314
649928603	304	20.57	112	277	11	173	9.0e-11	61.1	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
649928608	413	23.31	45	400	41	402	4.0e-37	149	COG3464	Transposase	402
649928609	445	28.21	6	319	24	326	8.0e-31	128	COG3344	Retron-type reverse transcriptase	328
649928610	1091	19.88	495	833	5	342	7.0e-07	50.6	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649928612	291	31.15	125	246	25	143	7.0e-08	51.5	COG0681	Signal peptidase I	166
649928616	251	32.71	1	250	4	262	9.0e-37	147	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
649928617	340	24.8	1	337	1	378	2.0e-19	90.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649928618	440	28.57	6	440	10	442	7.0e-64	238	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
649928619	265	34.52	3	263	5	282	1.0e-26	113	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649928621	599	29.52	11	595	48	692	3.0e-87	316	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
649928622	1116	34.5	220	1055	335	1139	0.0e+00	487	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
649928623	1082	38.34	5	1062	4	1069	0.0e+00	782	COG1330	Exonuclease V gamma subunit	1078
649928625	346	22.41	90	344	2	259	1.0e-11	64.2	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
649928626	402	49	1	400	1	394	0.0e+00	481	COG0282	Acetate kinase	396
649928627	367	49.86	4	364	12	367	1.0e-118	419	COG2021	Homoserine acetyltransferase	368
649928629	287	43.71	2	286	1	286	3.0e-64	238	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
649928633	149	60.69	1	145	1	145	6.0e-55	206	COG1490	D-Tyr-tRNAtyr deacylase	145
649928634	172	51.43	1	169	1	174	1.0e-42	165	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
649928635	283	39.93	1	281	1	275	1.0e-70	259	COG0648	Endonuclease IV	280
649928636	145	28.35	16	137	16	138	3.0e-15	74.3	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
649928637	276	45.88	1	276	1	270	5.0e-85	307	COG0253	Diaminopimelate epimerase	272
649928639	152	36.99	1	146	1	145	1.0e-35	142	COG1959	DNA-binding transcriptional regulator, IscR family	150
649928640	268	44.49	6	268	5	263	5.0e-68	251	COG1606	ATP-utilizing enzyme, PP-loop superfamily	269
649928641	140	34.06	7	139	1	138	5.0e-18	83.5	COG0071	Molecular chaperone IbpA, HSP20 family	146
649928644	892	53.32	293	892	2	593	0.0e+00	693	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
649928646	283	25.42	10	237	12	244	6.0e-26	111	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
649928647	638	38.98	140	622	3	500	4.0e-118	418	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649928648	232	33.7	45	224	3	179	7.0e-20	90.8	COG2840	DNA-nicking endonuclease, Smr domain	184
649928649	300	35.64	5	300	5	306	3.0e-47	182	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
649928651	98	48.48	1	98	1	99	1.0e-25	107	COG0011	Uncharacterized conserved protein YqgV, UPF0045/DUF77 family	100
649928653	134	45.74	1	129	1	128	6.0e-35	139	COG5015	Uncharacterized protein, pyridoxamine 5'-phosphate oxidase (PNPOx-like) family	132
649928654	141	34.62	32	135	19	122	8.0e-10	56.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
649928656	248	38.98	1	247	4	256	5.0e-44	171	COG0725	ABC-type molybdate transport system, periplasmic component	258
649928658	177	38.31	12	163	3	156	2.0e-28	118	COG0680	Ni,Fe-hydrogenase maturation factor	160
649928659	221	37.79	10	216	12	226	2.0e-34	139	COG1969	Ni,Fe-hydrogenase I cytochrome b subunit	227
649928660	565	57.88	1	563	1	543	0.0e+00	687	COG0374	Ni,Fe-hydrogenase I large subunit	545
649928661	379	49.86	23	375	3	355	2.0e-124	439	COG1740	Ni,Fe-hydrogenase I small subunit	355
649928662	212	39.05	3	212	1	209	3.0e-44	171	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649928665	377	33.5	173	377	79	284	1.0e-20	94.2	COG0842	ABC-type multidrug transport system, permease component	286
649928666	377	35.58	170	377	77	284	6.0e-23	102	COG0842	ABC-type multidrug transport system, permease component	286
649928667	320	40.39	4	307	1	291	2.0e-75	276	COG1131	ABC-type multidrug transport system, ATPase component	293
649928668	314	38.89	6	308	3	293	3.0e-72	265	COG1131	ABC-type multidrug transport system, ATPase component	293
649928669	332	29.24	1	332	12	344	2.0e-35	143	COG1566	Multidrug resistance efflux pump	352
649928670	445	23.28	32	432	43	443	4.0e-31	129	COG1538	Outer membrane protein TolC	457
649928671	212	28	19	193	5	178	1.0e-11	63.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649928673	268	27.13	39	267	9	237	5.0e-16	78.3	COG0528	Uridylate kinase	238
649928677	76	38.36	2	74	6	78	7.0e-10	55.4	COG4710	Predicted DNA-binding protein with an HTH domain	80
649928678	90	30	1	90	1	88	4.0e-12	63	COG2026	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system	90
649928681	143	49.21	1	119	3	116	4.0e-30	123	COG1970	Large-conductance mechanosensitive channel	130
649928682	459	33.99	178	329	36	187	1.0e-28	121	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
649928687	327	20.68	1	323	26	378	3.0e-33	135	COG1775	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB	379
649928689	363	42.28	1	356	2	370	4.0e-91	328	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
649928690	123	57.38	3	122	9	130	2.0e-32	131	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
649928691	445	39.51	3	442	12	447	8.0e-127	447	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
649928692	479	48.54	1	472	6	475	0.0e+00	576	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
649928693	266	31.62	3	262	1	246	1.0e-39	156	COG0095	Lipoate-protein ligase A	248
649928695	384	38.95	9	195	6	195	2.0e-32	133	COG2059	Chromate transport protein ChrA	195
649928696	288	52.16	3	278	21	298	9.0e-101	359	COG0320	Lipoate synthase	306
649928700	413	23.56	31	400	29	402	3.0e-37	149	COG3464	Transposase	402
649928701	291	27.52	98	246	1	143	6.0e-08	51.9	COG0681	Signal peptidase I	166
649928702	439	29.57	52	304	68	317	4.0e-29	122	COG3344	Retron-type reverse transcriptase	328
649928707	361	40.87	33	354	2	313	1.0e-73	270	COG2826	Transposase and inactivated derivatives, IS30 family	318
649928708	297	40.27	5	288	13	301	3.0e-59	221	COG4227	Antirestriction protein ArdC	316
649928711	106	35	11	70	5	64	2.0e-08	50.6	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
649928712	637	18.45	1	568	1	493	6.0e-24	106	COG3593	Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains	581
649928714	189	30.53	1	187	5	186	1.0e-21	96.5	COG1525	Endonuclease YncB, thermonuclease family	192
649928716	146	46.46	4	130	9	134	5.0e-38	150	COG3727	G:T-mismatch repair DNA endonuclease, very short patch repair protein	150
649928718	385	27.68	1	379	4	328	1.0e-43	170	COG0270	Site-specific DNA-cytosine methylase	328
649928725	356	28.14	94	345	40	294	5.0e-24	105	COG4974	Site-specific recombinase XerD	300
649928728	162	55.7	1	148	4	152	3.0e-48	184	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
649928729	139	44.12	1	135	1	136	4.0e-33	133	COG0864	Metal-responsive transcriptional regulator, contains CopG/Arc/MetJ DNA-binding domain	136
649928730	294	28.94	1	271	1	257	4.0e-31	128	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
649928731	158	25.35	12	151	26	167	9.0e-08	50	COG1633	Rubrerythrin	176
649928732	150	38.36	5	150	4	141	2.0e-30	124	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
649928733	173	30	36	170	9	156	1.0e-06	46.1	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
649928734	300	37.28	7	279	6	288	9.0e-56	210	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
649928736	226	37.09	1	205	4	215	4.0e-42	164	COG1878	Kynurenine formamidase	218
649928737	299	40.77	1	286	3	286	7.0e-72	264	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
649928739	823	39.88	38	365	1	346	3.0e-82	300	COG0826	Collagenase-like protease, PrtC family	347
649928741	339	61.29	59	337	8	286	5.0e-106	378	COG2876	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	286
649928742	149	42.36	7	149	16	159	2.0e-22	98.8	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
649928743	432	32.86	5	409	18	430	1.0e-63	237	COG0612	Predicted Zn-dependent peptidase	438
649928745	217	47.85	6	213	7	209	7.0e-52	197	COG2082	Precorrin isomerase	210
649928746	356	40.67	1	352	5	358	1.0e-74	273	COG1903	Cobalamin biosynthesis protein CbiD	367
649928747	405	44.68	216	402	1	186	4.0e-47	182	COG2242	Precorrin-6B methylase 2	187
649928748	236	40.25	1	235	1	231	4.0e-53	201	COG2243	Precorrin-2 methylase	234
649928749	261	60.16	7	257	5	252	7.0e-94	336	COG2875	Precorrin-4 methylase	254
649928750	349	32.32	50	345	42	297	1.0e-30	127	COG2073	Cobalamin biosynthesis protein CbiG	298
649928751	789	51.79	274	771	3	486	0.0e+00	565	COG1492	Cobyric acid synthase	486
649928751	789	58.96	1	250	2	248	1.0e-88	321	COG1010	Precorrin-3B methylase	249
649928752	321	49.36	6	316	4	315	9.0e-75	274	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
649928753	359	40.62	6	359	7	353	5.0e-72	264	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
649928755	144	34.97	1	143	4	145	1.0e-29	122	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
649928756	308	36.77	1	307	3	301	2.0e-62	232	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
649928757	250	37.5	3	250	2	247	4.0e-68	251	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
649928758	274	39.63	3	272	5	271	2.0e-36	146	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
649928759	385	41.67	164	342	3	181	2.0e-35	143	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649928760	476	36.22	48	476	1	438	1.0e-74	274	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
649928762	479	42.66	125	479	1	355	3.0e-96	345	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
649928763	221	66.2	1	213	3	214	6.0e-88	316	COG0036	Pentose-5-phosphate-3-epimerase	220
649928766	221	49.05	9	218	7	212	1.0e-71	262	COG2231	Uncharacterized protein related to Endonuclease III	215
649928767	2356	31.66	146	531	119	498	9.0e-14	74.3	COG1404	Serine protease, subtilisin family	508
649928768	187	51.43	1	175	3	170	4.0e-53	200	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
649928769	304	56.35	1	303	18	324	1.0e-110	393	COG0379	Quinolinate synthase	324
649928770	100	42.7	1	89	1	89	8.0e-12	62.3	COG1826	Sec-independent protein translocase protein TatA	94
649928773	283	26.58	74	279	39	257	2.0e-22	100	COG1729	Periplasmic TolA-binding protein (function unknown)	262
649928774	196	34.36	33	195	26	188	8.0e-31	126	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
649928775	406	33.33	6	406	3	425	2.0e-62	233	COG0823	Periplasmic component of the Tol biopolymer transport system	425
649928776	251	15.42	27	237	17	230	1.0e-04	40.5	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
649928777	139	43.48	1	138	1	137	2.0e-33	134	COG0848	Biopolymer transport protein ExbD	137
649928778	224	40.64	3	219	1	211	1.0e-42	166	COG0811	Biopolymer transport protein ExbB/TolQ	216
649928779	259	38.95	3	259	1	267	1.0e-50	193	COG0388	Predicted amidohydrolase	274
649928780	381	45.41	3	381	35	410	9.0e-104	370	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
649928781	344	42.11	4	344	3	343	2.0e-81	296	COG1420	Transcriptional regulator of heat shock response	346
649928782	189	40.21	3	187	6	193	3.0e-36	144	COG0576	Molecular chaperone GrpE (heat shock protein)	193
649928783	639	62.9	1	600	4	579	0.0e+00	696	COG0443	Molecular chaperone DnaK (HSP70)	579
649928784	372	59.34	6	367	3	365	0.0e+00	470	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
649928786	692	38.59	17	634	18	648	0.0e+00	510	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
649928787	234	62.56	1	227	1	227	2.0e-95	341	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
649928788	440	27.06	162	415	9	259	1.0e-22	100	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
649928798	279	28.33	38	265	30	269	3.0e-16	79.3	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
649928799	446	22.81	12	445	1	458	6.0e-16	79.2	COG1333	Cytochrome c biogenesis protein ResB	478
649928800	435	23.51	80	404	96	459	2.0e-24	107	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649928801	448	23.68	1	353	15	407	2.0e-26	114	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649928803	408	20.19	6	408	11	407	1.0e-20	94.6	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649928804	386	21.98	10	386	9	408	3.0e-19	89.9	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649928805	224	46.9	5	222	1	226	8.0e-73	266	COG1136	ABC-type lipoprotein export system, ATPase component	226
649928809	474	24.35	5	447	8	462	3.0e-45	176	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649928810	488	25.06	23	453	30	463	2.0e-42	167	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649928821	276	24.09	14	269	6	277	3.0e-12	65.8	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
649928825	504	23.47	26	430	31	446	6.0e-36	145	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649928827	225	44.78	1	224	1	229	1.0e-53	203	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649928828	484	31.04	140	470	1	327	2.0e-40	160	COG0642	Signal transduction histidine kinase	336
649928829	459	32.33	161	457	41	331	7.0e-41	161	COG0642	Signal transduction histidine kinase	336
649928830	237	46.46	3	226	1	223	3.0e-60	224	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649928831	174	27.94	2	136	4	136	5.0e-10	57.7	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
649928836	436	57.83	1	434	3	431	0.0e+00	625	COG0422	Thiamine biosynthesis protein ThiC	432
649928837	485	61.96	223	476	6	259	4.0e-95	342	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
649928838	379	44.18	4	379	3	360	5.0e-104	371	COG0787	Alanine racemase	360
649928839	343	42.24	36	337	38	340	1.0e-75	276	COG0709	Selenophosphate synthase	346
649928841	520	64.3	4	520	2	515	0.0e+00	764	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
649928842	423	57.04	1	423	1	425	0.0e+00	567	COG0151	Phosphoribosylamine-glycine ligase	428
649928843	168	50.62	4	165	3	162	1.0e-47	182	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
649928845	453	24.15	20	453	1	462	2.0e-51	197	COG1333	Cytochrome c biogenesis protein ResB	478
649928846	282	30.55	18	282	12	281	1.0e-28	120	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
649928849	314	27.15	1	288	3	285	8.0e-22	97.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649928850	394	25.95	6	392	3	381	1.0e-28	120	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649928853	388	31.08	9	333	1	294	1.0e-53	203	COG3980	Spore coat polysaccharide biosynthesis protein SpsG, predicted glycosyltransferase	318
649928855	523	18.9	1	470	3	460	7.0e-11	62.4	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
649928856	178	28.57	45	175	37	176	8.0e-18	83.4	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
649928857	363	33.88	3	349	13	368	2.0e-28	120	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
649928858	404	25.5	60	404	35	375	3.0e-30	126	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649928861	360	21.87	39	360	61	367	1.0e-17	84.5	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649928862	361	22.99	1	330	29	356	3.0e-28	119	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
649928863	325	22.15	9	292	4	286	1.0e-19	90.6	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649928864	397	25.06	1	392	1	375	1.0e-25	110	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649928866	267	38.08	13	251	5	242	1.0e-55	209	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
649928870	195	35.82	4	66	8	74	6.0e-09	54.1	COG0425	TusA-related sulfurtransferase	78
649928871	454	58.68	1	454	1	451	0.0e+00	590	COG0541	Signal recognition particle GTPase	451
649928872	88	56.1	2	82	1	82	6.0e-25	105	COG0228	Ribosomal protein S16	87
649928873	76	55.26	1	76	1	76	2.0e-15	74.1	COG1837	Predicted RNA-binding protein YlqC, contains KH domain, UPF0109 family	76
649928874	172	42.77	1	171	2	174	1.0e-41	162	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
649928875	261	61.09	1	238	1	238	8.0e-100	356	COG0336	tRNA G37 N-methylase TrmD	240
649928876	189	45.65	6	189	4	186	5.0e-56	210	COG4752	Uncharacterized protein	190
649928877	118	67.26	1	113	3	115	2.0e-39	154	COG0335	Ribosomal protein L19	115
649928878	228	51.08	28	208	2	186	4.0e-60	224	COG0164	Ribonuclease HII	199
649928879	125	48.21	11	121	5	112	3.0e-28	117	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
649928881	283	29.89	1	276	1	273	3.0e-36	145	COG0388	Predicted amidohydrolase	274
649928882	273	40.15	4	259	1	261	1.0e-67	250	COG0171	NH3-dependent NAD+ synthetase	268
649928883	276	53.99	1	275	3	275	3.0e-91	328	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
649928884	339	47.08	3	335	1	342	2.0e-93	336	COG2008	Threonine aldolase	342
649928885	530	34.92	21	467	3	435	5.0e-87	315	COG0166	Glucose-6-phosphate isomerase	446
649928887	322	38.15	5	322	4	322	3.0e-73	268	COG0142	Geranylgeranyl pyrophosphate synthase	322
649928889	453	50	1	447	3	456	0.0e+00	507	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649928890	171	28.95	30	167	6	155	6.0e-15	73.7	COG1225	Peroxiredoxin	157
649928891	238	43.38	6	220	11	219	1.0e-32	133	COG0785	Cytochrome c biogenesis protein CcdA	220
649928894	360	25.7	1	354	1	357	1.0e-43	170	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
649928895	387	26.94	3	357	2	360	2.0e-46	179	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
649928896	227	33.33	6	215	1	210	1.0e-33	136	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
649928899	836	30.22	382	834	6	464	4.0e-65	243	COG1109	Phosphomannomutase	464
649928899	836	38.13	1	372	2	358	2.0e-91	331	COG1208	NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins	358
649928900	738	29.49	2	538	1	496	2.0e-71	264	COG1449	Alpha-amylase/alpha-mannosidase, GH57 family	615
649928901	486	43.92	1	479	1	479	0.0e+00	480	COG0297	Glycogen synthase	487
649928904	266	43.5	17	262	10	247	7.0e-63	234	COG1496	Copper oxidase (laccase) domain	249
649928905	319	50	4	304	2	289	1.0e-79	289	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
649928907	477	48.48	55	378	35	347	1.0e-76	280	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649928908	206	22.22	21	136	2	118	5.0e-07	47.7	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
649928914	506	22.31	138	505	17	346	1.0e-22	101	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649928915	230	62.33	7	229	1	222	6.0e-100	356	COG0692	Uracil DNA glycosylase	223
649928916	532	36.15	188	530	68	406	1.0e-44	174	COG0840	Methyl-accepting chemotaxis protein	408
649928917	732	30.65	127	447	26	336	4.0e-41	163	COG0642	Signal transduction histidine kinase	336
649928918	290	26.77	5	258	9	262	8.0e-34	137	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
649928920	308	28.17	9	284	3	284	4.0e-12	65.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
649928921	261	30.48	1	253	1	267	4.0e-36	144	COG0266	Formamidopyrimidine-DNA glycosylase	273
649928923	175	20.61	2	130	1	120	3.0e-03	34.9	COG3133	Outer membrane lipoprotein SlyB	154
649928924	517	35.1	12	508	17	511	8.0e-67	248	COG0815	Apolipoprotein N-acyltransferase	518
649928925	709	47.61	11	696	9	694	0.0e+00	725	COG1523	Pullulanase/glycogen debranching enzyme	697
649928926	360	55.46	1	355	1	352	2.0e-129	455	COG0082	Chorismate synthase	369
649928931	170	28.32	1	161	51	219	4.0e-19	87.8	COG1451	Predicted metal-dependent hydrolase	223
649928932	389	50.9	1	383	4	388	5.0e-122	431	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
649928933	268	29.33	1	268	1	282	2.0e-27	115	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649928934	273	27.98	1	161	4	170	3.0e-20	92.6	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
649928935	561	46.57	9	539	3	527	0.0e+00	567	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
649928937	492	59.39	1	490	7	501	0.0e+00	688	COG1190	Lysyl-tRNA synthetase (class II)	502
649928938	416	43.3	1	416	3	408	6.0e-98	351	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649928939	226	50	4	224	1	222	2.0e-78	285	COG1136	ABC-type lipoprotein export system, ATPase component	226
649928940	805	33.68	63	805	26	766	0.0e+00	555	COG4775	Outer membrane protein assembly factor BamA	766
649928941	171	24.26	1	167	2	169	3.0e-13	68.1	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
649928942	346	49.4	4	334	5	338	4.0e-95	341	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
649928943	144	53.42	1	144	3	146	8.0e-43	166	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
649928944	258	60.7	2	258	6	260	4.0e-97	347	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
649928945	380	38.46	8	380	4	380	8.0e-100	357	COG0763	Lipid A disaccharide synthetase	381
649928946	581	39.75	10	579	1	565	0.0e+00	500	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
649928947	310	31.08	8	300	15	300	6.0e-50	191	COG1560	Lauroyl/myristoyl acyltransferase	308
649928948	435	41.92	6	428	5	419	8.0e-103	367	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
649928949	363	36.67	23	348	15	324	1.0e-60	227	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
649928950	351	24.57	1	346	2	331	2.0e-46	179	COG0859	ADP-heptose:LPS heptosyltransferase	334
649928952	392	42.46	4	392	1	372	4.0e-112	398	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649928953	230	33.48	2	228	4	227	2.0e-55	208	COG1083	CMP-N-acetylneuraminic acid synthetase	228
649928954	191	26.7	15	180	12	187	4.0e-17	81.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
649928955	352	47.71	3	350	1	347	1.0e-116	413	COG2089	Sialic acid synthase SpsE, contains C-terminal SAF domain	347
649928957	337	31.1	3	336	2	314	8.0e-52	197	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649928960	487	51.48	16	487	11	467	0.0e+00	535	COG2870	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase	467
649928961	350	71.3	1	344	2	345	0.0e+00	565	COG1089	GDP-D-mannose dehydratase	345
649928962	309	32.61	6	308	2	312	4.0e-44	171	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649928963	206	16.76	32	201	9	182	1.0e-06	46.9	COG3117	Lipopolysaccharide export system protein LptC	188
649928964	165	25.29	2	165	4	171	5.0e-23	100	COG1934	Lipopolysaccharide export system protein LptA	173
649928965	245	63.22	6	245	2	243	2.0e-103	368	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
649928966	515	38.4	3	513	1	442	2.0e-111	396	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
649928967	182	40.95	1	103	1	105	2.0e-19	89.1	COG1544	Ribosome-associated translation inhibitor RaiA	110
649928968	316	44.63	1	307	1	303	1.0e-81	296	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
649928969	287	48.08	1	285	1	286	3.0e-94	338	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
649928970	131	36.72	1	124	1	128	3.0e-20	90.7	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
649928971	88	53.41	1	88	1	88	1.0e-24	104	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
649928972	586	51.68	9	574	1	567	0.0e+00	637	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
649928973	257	27.72	7	194	4	205	2.0e-19	89.7	COG0775	Nucleoside phosphorylase	234
649928974	473	25	47	441	52	457	5.0e-33	135	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649928975	288	28.77	2	282	3	256	7.0e-32	131	COG3394	Predicted glycoside hydrolase or deacetylase ChbG, UPF0249 family	257
649928978	460	44.4	1	460	1	435	0.0e+00	510	COG0017	Aspartyl/asparaginyl-tRNA synthetase	435
649928980	122	26.23	40	98	1	61	2.0e-09	54.6	COG0695	Glutaredoxin	80
649928981	325	31.88	1	319	7	350	7.0e-58	217	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
649928983	320	28	43	311	38	311	4.0e-39	155	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
649928984	168	25.16	15	166	9	150	7.0e-10	56.8	COG1406	Chemotaxis protein CheX, a CheY~P-specific phosphatase	153
649928986	541	38.76	40	345	1	296	4.0e-86	312	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
649928987	293	27.46	4	282	3	293	7.0e-34	137	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
649928988	484	28.66	174	481	37	331	3.0e-36	146	COG0642	Signal transduction histidine kinase	336
649928989	447	50.88	1	447	2	453	0.0e+00	476	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649928992	267	42.72	62	267	4	205	2.0e-41	162	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
649928995	468	36.47	63	319	58	323	2.0e-48	187	COG3344	Retron-type reverse transcriptase	328
649928998	235	42.98	1	233	3	235	1.0e-64	239	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
649928999	389	37.07	9	237	16	247	2.0e-46	180	COG1624	Diadenylate cyclase (c-di-AMP synthetase), DisA_N domain	247
649929001	568	29.16	23	462	31	483	6.0e-49	189	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649929004	753	30.37	38	750	13	707	5.0e-114	405	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
649929005	305	54.52	1	293	1	299	9.0e-108	383	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
649929006	559	40.58	1	520	4	509	1.0e-122	433	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
649929007	110	27.96	1	93	4	96	2.0e-03	34.5	COG3937	Polyhydroxyalkanoate synthesis regulator phasin	108
649929008	628	44.26	142	628	14	499	0.0e+00	494	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649929009	183	49.42	5	176	2	173	7.0e-64	236	COG0225	Peptide methionine sulfoxide reductase MsrA	174
649929011	411	47.51	9	407	5	381	2.0e-120	426	COG0448	ADP-glucose pyrophosphorylase	393
649929012	419	29.11	43	277	32	255	7.0e-30	125	COG3016	Uncharacterized iron-regulated protein	295
649929013	362	55.8	5	362	4	345	2.0e-126	446	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
649929015	365	29.78	1	362	2	333	3.0e-88	318	COG0136	Aspartate-semialdehyde dehydrogenase	334
649929016	341	58.88	6	336	1	334	8.0e-120	423	COG0136	Aspartate-semialdehyde dehydrogenase	334
649929017	250	45.93	1	246	1	246	3.0e-83	301	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
649929018	142	57.34	1	142	1	143	5.0e-48	183	COG0102	Ribosomal protein L13	148
649929019	129	62.79	1	129	2	130	6.0e-47	179	COG0103	Ribosomal protein S9	130
649929020	346	59.89	1	346	2	349	0.0e+00	469	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
649929021	601	21.99	34	586	2	487	9.0e-45	175	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649929026	396	85.1	1	396	1	394	0.0e+00	707	COG0050	Translation elongation factor EF-Tu, a GTPase	394
649929027	50	66	1	50	1	50	3.0e-10	56.8	COG0267	Ribosomal protein L33	50
649929029	61	40.74	4	57	19	72	1.0e-05	41.5	COG0690	Preprotein translocase subunit SecE	73
649929030	175	51.41	1	175	1	177	3.0e-48	184	COG0250	Transcription antitermination factor NusG	178
649929031	140	73.19	2	139	1	138	3.0e-52	197	COG0080	Ribosomal protein L11	141
649929032	233	60.44	3	226	4	228	7.0e-77	280	COG0081	Ribosomal protein L1	228
649929033	173	43.93	1	173	3	175	1.0e-37	149	COG0244	Ribosomal protein L10	175
649929034	126	70.63	1	126	1	124	1.0e-23	101	COG0222	Ribosomal protein L7/L12	124
649929036	1381	49.07	19	847	6	808	0.0e+00	857	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
649929037	123	78.05	1	123	7	129	1.0e-48	185	COG0048	Ribosomal protein S12	129
649929038	156	59.46	2	149	1	148	1.0e-52	198	COG0049	Ribosomal protein S7	148
649929039	692	70.26	1	692	1	693	0.0e+00	1027	COG0480	Translation elongation factor EF-G, a GTPase	697
649929040	396	85.1	1	396	1	394	0.0e+00	707	COG0050	Translation elongation factor EF-Tu, a GTPase	394
649929041	102	71.57	1	102	1	102	3.0e-38	149	COG0051	Ribosomal protein S10	104
649929042	211	52.11	3	211	2	214	2.0e-65	242	COG0087	Ribosomal protein L3	218
649929043	207	43.87	1	207	1	212	3.0e-48	185	COG0088	Ribosomal protein L4	214
649929044	94	55.43	4	94	2	93	2.0e-19	87.6	COG0089	Ribosomal protein L23	94
649929045	274	62.91	1	274	1	275	7.0e-110	390	COG0090	Ribosomal protein L2	275
649929046	93	65.59	1	92	1	93	1.0e-32	131	COG0185	Ribosomal protein S19	93
649929047	111	56.76	1	111	9	119	9.0e-31	125	COG0091	Ribosomal protein L22	120
649929048	211	64.36	12	211	1	202	2.0e-74	272	COG0092	Ribosomal protein S3	233
649929049	140	60.56	1	140	2	143	6.0e-50	189	COG0197	Ribosomal protein L16/L10AE	146
649929050	62	49.18	2	62	4	64	1.0e-06	44.5	COG0255	Ribosomal protein L29	69
649929051	85	57.32	1	82	2	83	5.0e-20	89.1	COG0186	Ribosomal protein S17	87
649929052	122	74.59	1	122	1	122	1.0e-48	184	COG0093	Ribosomal protein L14	122
649929053	108	54.72	4	107	1	104	2.0e-18	84.2	COG0198	Ribosomal protein L24	104
649929054	179	62.57	1	179	1	179	9.0e-73	265	COG0094	Ribosomal protein L5	180
649929055	61	50.82	1	61	1	61	1.0e-14	71.8	COG0199	Ribosomal protein S14	61
649929056	132	57.58	1	132	1	132	2.0e-46	177	COG0096	Ribosomal protein S8	132
649929057	179	58.66	1	178	1	178	4.0e-52	197	COG0097	Ribosomal protein L6P/L9E	178
649929058	122	52.42	1	122	2	125	4.0e-33	133	COG0256	Ribosomal protein L18	125
649929059	162	63.16	10	161	23	174	2.0e-54	205	COG0098	Ribosomal protein S5	181
649929060	58	52.73	4	58	1	55	9.0e-11	58.6	COG1841	Ribosomal protein L30/L7E	55
649929061	146	56.95	1	146	1	151	2.0e-35	141	COG0200	Ribosomal protein L15	152
649929062	435	48.85	1	427	6	432	3.0e-121	429	COG0201	Preprotein translocase subunit SecY	436
649929063	216	43.4	1	212	1	177	2.0e-49	189	COG0563	Adenylate kinase or related kinase	178
649929064	248	52.8	1	247	2	251	1.0e-82	299	COG0024	Methionine aminopeptidase	255
649929065	37	73.68	1	37	1	38	2.0e-03	34	COG0257	Ribosomal protein L36	38
649929066	122	63.64	1	121	1	121	6.0e-43	166	COG0099	Ribosomal protein S13	121
649929067	131	72.22	6	131	4	129	1.0e-47	181	COG0100	Ribosomal protein S11	129
649929068	208	56.19	1	208	1	205	8.0e-58	216	COG0522	Ribosomal protein S4 or related protein	205
649929069	339	49.52	12	326	3	314	2.0e-91	329	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
649929070	167	65.52	1	116	1	116	7.0e-44	169	COG0203	Ribosomal protein L17	116
649929071	1177	35.53	1	1177	1	1158	0.0e+00	594	COG1196	Chromosome segregation ATPase	1163
649929072	119	22.22	2	91	4	92	2.0e-05	41.3	COG2018	Predicted regulator of Ras-like GTPase activity, Roadblock/LC7/MglB family	119
649929073	403	54.43	94	402	24	339	7.0e-105	374	COG0552	Signal recognition particle GTPase	340
649929076	193	38.1	1	184	3	191	3.0e-37	148	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
649929077	533	47.09	312	533	1	222	7.0e-46	178	COG1418	HD superfamily phosphodieaserase, includes HD domain of RNase Y	222
649929078	262	55.81	3	259	1	257	6.0e-96	344	COG1692	Calcineurin-like phosphoesterase	266
649929079	403	44.61	1	401	1	399	1.0e-115	410	COG0162	Tyrosyl-tRNA synthetase	401
649929085	800	50.32	33	800	10	776	0.0e+00	981	COG0466	ATP-dependent Lon protease, bacterial type	782
649929086	228	32.86	20	227	11	185	1.0e-22	99.9	COG0693	Putative intracellular protease/amidase	188
649929087	299	38.67	1	298	1	276	9.0e-64	237	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
649929088	228	40.53	31	217	2	190	8.0e-33	133	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
649929089	287	30	14	283	7	280	5.0e-23	101	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649929090	472	23.16	13	387	23	403	3.0e-23	103	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649929093	411	23.11	31	279	27	276	3.0e-22	99.6	COG0826	Collagenase-like protease, PrtC family	347
649929094	362	29.46	17	360	2	351	3.0e-52	199	COG3424	Predicted naringenin-chalcone synthase	356
649929095	470	28.42	17	384	25	408	5.0e-38	152	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649929097	873	48.98	184	858	11	688	0.0e+00	743	COG0855	Polyphosphate kinase	696
649929099	567	41.28	24	567	1	561	0.0e+00	561	COG1151	Hydroxylamine reductase (hybrid-cluster protein)	576
649929101	410	23.14	1	387	1	384	1.0e-25	111	COG2814	Predicted arabinose efflux permease, MFS family	394
649929102	301	34.88	1	296	1	295	2.0e-43	169	COG0583	DNA-binding transcriptional regulator, LysR family	297
649929106	594	24.93	237	586	124	459	4.0e-28	120	COG5002	Signal transduction histidine kinase	459
649929107	362	53.09	3	357	2	348	2.0e-115	409	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
649929108	288	48.51	27	284	1	263	4.0e-71	261	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
649929109	579	45.59	203	517	69	408	4.0e-55	209	COG0840	Methyl-accepting chemotaxis protein	408
649929110	174	37.8	1	164	1	164	2.0e-37	148	COG0835	Chemotaxis signal transduction protein	165
649929111	686	40.42	12	685	5	711	0.0e+00	578	COG0643	Chemotaxis protein histidine kinase CheA	716
649929112	114	18.02	5	114	10	115	9.0e-05	38.8	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
649929114	289	31.31	68	281	1	214	7.0e-31	128	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
649929115	377	41	140	377	9	226	6.0e-59	221	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
649929116	341	25.36	1	330	3	331	9.0e-42	164	COG0673	Predicted dehydrogenase	342
649929117	177	39.07	17	158	31	178	1.0e-17	82.6	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
649929118	354	46.02	5	347	21	370	2.0e-110	392	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649929120	228	24.53	1	207	6	213	2.0e-18	86.3	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
649929121	485	20.51	18	464	17	456	4.0e-32	132	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
649929122	384	31.44	1	261	9	269	2.0e-39	156	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
649929124	349	33.71	7	349	2	342	2.0e-50	193	COG1817	Predicted glycosyltransferase	346
649929125	450	23.15	20	437	3	412	9.0e-14	71.7	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
649929127	365	23.22	10	359	4	381	1.0e-32	133	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929131	329	29.6	12	327	1	267	1.0e-51	197	COG0171	NH3-dependent NAD+ synthetase	268
649929132	97	30.38	1	79	4	79	6.0e-08	49.2	COG0236	Acyl carrier protein	80
649929135	365	41.64	1	364	3	348	2.0e-63	236	COG1290	Cytochrome b subunit of the bc complex	381
649929136	139	29.94	5	139	10	165	6.0e-19	86.8	COG0723	Rieske Fe-S protein	177
649929137	110	26.32	6	100	17	111	1.0e-10	58.1	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
649929138	319	22.7	31	283	20	284	3.0e-10	59.2	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649929139	65	35.94	7	64	5	68	3.0e-06	43.4	COG1141	Ferredoxin	68
649929140	369	31.95	39	369	1	331	1.0e-40	160	COG0642	Signal transduction histidine kinase	336
649929141	138	38.71	35	96	4	65	4.0e-10	57.3	COG2608	Copper chaperone CopZ	71
649929156	101	38.75	15	94	9	88	1.0e-11	61.5	COG4453	Uncharacterized conserved protein, DUF1778 family	95
649929163	402	19.51	1	395	1	381	2.0e-16	80.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929164	354	21.22	1	342	1	377	1.0e-24	107	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929165	311	17.97	4	279	1	290	4.0e-14	72.5	COG1216	Glycosyltransferase, GT2 family	305
649929166	406	25.3	1	406	1	380	3.0e-42	166	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929168	498	31.57	3	424	1	397	1.0e-60	227	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
649929169	114	43.4	7	112	8	110	3.0e-15	73.8	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
649929171	79	25.97	1	77	4	80	1.0e-04	38	COG0236	Acyl carrier protein	80
649929172	539	35.25	3	535	4	528	0.0e+00	499	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
649929176	1687	28.15	417	768	18	381	4.0e-36	148	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929177	708	21.91	442	708	98	380	2.0e-23	105	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929180	973	31.54	3	378	2	377	8.0e-39	156	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929181	316	26.56	2	226	1	241	4.0e-21	96	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649929182	214	58.85	6	197	1	192	3.0e-78	284	COG0529	Adenylylsulfate kinase or related kinase	197
649929183	592	19.91	125	591	66	458	3.0e-27	117	COG0471	Di- and tricarboxylate transporter	461
649929185	291	25.54	36	242	8	233	1.0e-14	74.3	COG4424	LPS sulfotransferase NodH	250
649929188	428	49.17	4	243	2	243	1.0e-82	300	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
649929189	269	29.7	4	269	3	263	6.0e-32	131	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
649929193	233	20.18	1	210	3	210	6.0e-13	67.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649929194	336	33.69	1	271	3	284	7.0e-51	194	COG1216	Glycosyltransferase, GT2 family	305
649929197	450	30.97	291	445	34	188	2.0e-26	113	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
649929201	393	22.47	1	386	1	380	5.0e-19	88.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929205	166	28.77	12	156	7	149	3.0e-09	55	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
649929210	229	31.31	36	228	1	195	4.0e-33	134	COG0288	Carbonic anhydrase	207
649929213	278	30.82	1	278	3	258	8.0e-18	84.3	COG0730	Uncharacterized membrane protein YfcA	258
649929216	332	22.86	1	139	1	136	5.0e-13	68.7	COG1943	REP element-mobilizing transposase RayT	136
649929222	157	42.67	9	157	6	154	6.0e-31	126	COG1522	DNA-binding transcriptional regulator, Lrp family	154
649929223	371	60.27	1	370	1	370	0.0e+00	479	COG0686	Alanine dehydrogenase	371
649929224	284	25.16	1	284	7	310	7.0e-19	88	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
649929225	648	21.43	71	648	33	608	6.0e-30	126	COG4206	Outer membrane cobalamin receptor protein	608
649929227	335	25	80	334	53	305	2.0e-11	63.6	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
649929240	224	41.86	6	220	2	211	4.0e-52	197	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649929246	62	35.94	5	61	3	66	4.0e-10	56.1	COG1141	Ferredoxin	68
649929249	361	26.12	17	304	2	292	3.0e-17	83	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
649929250	162	68.52	1	162	1	162	2.0e-68	250	COG1839	Adenosine/AMP kinase	162
649929253	201	38.07	1	193	3	195	8.0e-47	180	COG0288	Carbonic anhydrase	207
649929258	212	33.66	4	207	2	205	3.0e-34	138	COG2085	Predicted dinucleotide-binding enzyme	211
649929261	446	32.77	16	301	32	327	3.0e-44	173	COG3344	Retron-type reverse transcriptase	328
649929264	244	25	1	209	1	209	2.0e-12	65.9	COG3361	Uncharacterized protein YqjF, DUF2071 family	240
649929265	446	32.77	16	301	32	327	3.0e-44	173	COG3344	Retron-type reverse transcriptase	328
649929266	745	34.44	13	580	102	652	3.0e-128	453	COG0209	Ribonucleotide reductase alpha subunit	696
649929269	239	58.23	3	238	9	230	2.0e-72	265	COG0689	Ribonuclease PH	230
649929270	207	53.61	1	194	1	191	2.0e-62	232	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
649929275	176	50.29	11	173	13	179	6.0e-39	153	COG2032	Cu/Zn superoxide dismutase	179
649929276	197	51.81	1	192	1	192	2.0e-50	192	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
649929277	145	33.64	32	140	15	124	3.0e-11	61.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
649929279	430	41.8	4	428	7	435	7.0e-98	351	COG1030	Membrane-bound serine protease (ClpP class)	436
649929283	474	38.73	11	466	7	452	6.0e-102	365	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649929284	244	65	1	240	2	240	9.0e-112	396	COG1126	ABC-type polar amino acid transport system, ATPase component	240
649929285	273	37.69	10	259	8	267	2.0e-38	152	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
649929286	234	40.71	4	228	1	218	2.0e-55	208	COG0765	ABC-type amino acid transport system, permease component	222
649929287	233	40.91	11	230	3	221	2.0e-52	199	COG0765	ABC-type amino acid transport system, permease component	222
649929289	206	23.33	27	204	35	207	2.0e-17	82.5	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
649929290	207	30.65	26	206	29	205	5.0e-20	91.2	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649929291	453	17.66	38	388	13	292	1.0e-11	64.6	COG1566	Multidrug resistance efflux pump	352
649929292	725	34.43	24	722	12	700	0.0e+00	541	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
649929294	657	31.98	413	656	4	248	2.0e-40	161	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
649929295	224	30.77	5	196	10	191	5.0e-33	134	COG3672	Predicted transglutaminase-like cysteine proteinase	191
649929296	440	23.46	9	420	26	447	2.0e-34	140	COG1538	Outer membrane protein TolC	457
649929299	541	35.66	1	258	9	264	5.0e-42	166	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
649929301	729	35.46	13	724	1	692	3.0e-117	416	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
649929302	235	42.42	1	230	1	230	4.0e-60	224	COG1794	Aspartate/glutamate racemase	230
649929303	204	26.24	4	197	6	207	3.0e-13	68.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
649929307	193	41.9	15	193	23	198	2.0e-49	188	COG2109	ATP:corrinoid adenosyltransferase	198
649929308	224	39.63	7	221	9	223	1.0e-24	106	COG2836	Sulfite exporter TauE/SafE	232
649929309	91	34.48	2	59	1	58	2.0e-08	51	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
649929310	801	44.66	85	797	4	709	0.0e+00	683	COG2217	Cation transport ATPase	713
649929312	408	29.1	8	366	5	377	2.0e-36	147	COG0348	Polyferredoxin	386
649929315	287	41.4	2	187	6	219	2.0e-55	209	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
649929316	467	46.9	3	464	7	473	0.0e+00	476	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
649929318	549	39.75	1	548	2	561	0.0e+00	548	COG1151	Hydroxylamine reductase (hybrid-cluster protein)	576
649929325	243	30.97	15	240	6	217	6.0e-42	164	COG2846	Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains	221
649929326	139	32.06	1	130	1	129	4.0e-15	73.8	COG2703	Hemerythrin	144
649929327	318	41.15	91	316	20	243	1.0e-54	207	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
649929328	454	24.55	5	211	2	220	6.0e-15	75.6	COG1192	Cellulose biosynthesis protein BcsQ	259
649929329	458	50.45	9	448	5	440	8.0e-130	457	COG1570	Exonuclease VII, large subunit	440
649929330	75	44	1	75	7	81	2.0e-06	44.2	COG1722	Exonuclease VII small subunit	81
649929331	295	39.52	1	295	1	322	2.0e-69	255	COG0142	Geranylgeranyl pyrophosphate synthase	322
649929332	650	59.39	3	621	3	621	0.0e+00	864	COG1154	Deoxyxylulose-5-phosphate synthase	627
649929334	125	48	1	125	1	125	4.0e-36	143	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
649929335	513	43.73	233	510	19	284	7.0e-57	215	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
649929337	154	48.99	4	151	3	149	2.0e-41	161	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
649929338	405	43.81	1	403	1	447	4.0e-113	401	COG0527	Aspartokinase	447
649929339	528	34.52	4	423	3	409	1.0e-97	351	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
649929343	136	36.76	2	136	1	136	2.0e-31	127	COG1959	DNA-binding transcriptional regulator, IscR family	150
649929344	447	48.65	1	440	2	446	3.0e-130	458	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
649929345	342	43.11	1	333	5	341	3.0e-68	252	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
649929346	435	41.11	1	431	1	430	5.0e-86	311	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
649929347	199	71.35	1	192	2	193	6.0e-85	306	COG0740	ATP-dependent protease ClpP, protease subunit	200
649929348	417	70.37	14	417	1	404	0.0e+00	660	COG1219	ATP-dependent protease Clp, ATPase subunit	408
649929349	806	61.22	14	782	6	776	0.0e+00	1111	COG0466	ATP-dependent Lon protease, bacterial type	782
649929350	91	56.04	1	91	2	92	3.0e-26	109	COG0776	Bacterial nucleoid DNA-binding protein	94
649929356	401	36.07	1	401	1	397	1.0e-86	313	COG1459	Type II secretory pathway, component PulF	397
649929357	573	45.69	64	571	2	499	0.0e+00	514	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649929363	163	23.9	8	163	7	149	2.0e-07	48.9	COG2165	Type II secretory pathway, pseudopilin PulG	149
649929364	137	34.17	5	118	1	120	2.0e-14	71.6	COG4968	Tfp pilus assembly protein PilE	139
649929365	223	53.49	1	215	1	215	8.0e-75	273	COG2884	ABC-type ATPase involved in cell division	223
649929366	315	31.79	18	315	2	297	3.0e-43	169	COG2177	Cell division protein FtsX	297
649929367	400	27.25	2	400	14	419	9.0e-51	194	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
649929368	444	45.48	39	407	35	406	3.0e-98	352	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
649929369	485	50.85	14	481	3	467	0.0e+00	543	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
649929370	258	36	9	251	17	266	1.0e-49	190	COG1526	Formate dehydrogenase assembly factor FdhD	266
649929373	839	64.96	1	839	1	840	0.0e+00	1224	COG1049	Aconitase B	852
649929374	588	34.63	4	588	10	596	2.0e-111	396	COG1164	Oligoendopeptidase F	598
649929376	237	23.77	10	220	1	222	5.0e-19	88	COG1011	FMN phosphatase YigB, HAD superfamily	229
649929377	458	30.26	1	457	1	411	1.0e-93	337	COG0498	Threonine synthase	411
649929378	159	45.28	1	159	1	153	2.0e-38	151	COG0779	Ribosome maturation factor RimP	153
649929379	397	55.38	158	342	1	180	1.0e-47	184	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
649929380	197	40.86	1	93	2	90	3.0e-15	75	COG2740	Predicted RNA-binding protein YlxR, DUF448 family	95
649929381	970	61.93	468	970	1	507	0.0e+00	672	COG0532	Translation initiation factor IF-2, a GTPase	509
649929382	119	44.25	4	115	6	118	5.0e-31	126	COG0858	Ribosome-binding factor A	118
649929383	322	29.69	7	320	5	322	3.0e-47	182	COG0618	nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs	332
649929384	295	39.26	1	295	13	270	3.0e-61	228	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
649929385	88	61.36	1	88	2	89	4.0e-25	106	COG0184	Ribosomal protein S15P/S13E	89
649929386	696	59.04	1	691	3	692	0.0e+00	920	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
649929387	418	37.44	1	404	16	429	1.0e-87	317	COG0612	Predicted Zn-dependent peptidase	438
649929388	146	63.16	14	146	16	147	6.0e-49	186	COG0756	dUTPase	148
649929389	367	31.87	3	363	1	385	8.0e-76	277	COG2309	Leucyl aminopeptidase (aminopeptidase T)	385
649929390	202	41.5	1	198	2	201	7.0e-56	210	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
649929392	122	36.61	1	111	2	113	2.0e-23	101	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
649929393	250	27.46	5	248	3	210	1.0e-27	116	COG0602	Organic radical activating enzyme	212
649929394	314	41.72	1	313	5	329	3.0e-65	241	COG0714	MoxR-like ATPase	329
649929395	288	19.4	1	283	1	298	6.0e-19	88.3	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
649929396	628	22.59	289	523	84	319	1.0e-16	82.1	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
649929399	749	57.18	1	429	15	431	0.0e+00	552	COG0281	Malic enzyme	432
649929400	160	37.31	20	151	2	134	4.0e-27	113	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
649929401	302	38.56	6	300	8	311	2.0e-51	196	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
649929402	236	24.17	7	236	4	240	1.0e-13	70.6	COG1651	Protein-disulfide isomerase	244
649929403	415	33.81	1	414	1	390	9.0e-70	257	COG1379	PHP family phosphoesterase with a Zn ribbon	403
649929404	133	26.27	12	129	2	117	2.0e-15	74.4	COG0789	DNA-binding transcriptional regulator, MerR family	124
649929405	293	25	9	287	1	285	4.0e-38	151	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
649929409	258	37.02	1	257	1	260	2.0e-52	199	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
649929410	303	41.03	1	303	1	312	1.0e-70	260	COG2025	Electron transfer flavoprotein, alpha subunit	313
649929412	668	54.48	1	666	2	665	0.0e+00	875	COG0272	NAD-dependent DNA ligase	667
649929413	678	44.12	5	642	1	639	0.0e+00	569	COG0210	Superfamily I DNA or RNA helicase	655
649929414	209	49.44	35	206	5	181	7.0e-59	220	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
649929415	171	50.3	9	171	2	158	6.0e-49	186	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
649929417	389	66.41	3	388	2	387	0.0e+00	648	COG0192	S-adenosylmethionine synthetase	388
649929418	258	41.74	6	234	1	229	3.0e-57	215	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649929420	363	26.92	1	357	2	328	3.0e-48	185	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
649929422	464	57.3	1	456	1	420	0.0e+00	639	COG0499	S-adenosylhomocysteine hydrolase	420
649929423	414	45.39	1	399	6	404	5.0e-105	374	COG0303	Molybdopterin biosynthesis enzyme	404
649929424	283	35.09	49	266	10	235	8.0e-40	157	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
649929425	74	26.19	2	74	1	84	7.0e-04	35.7	COG1977	Molybdopterin converting factor, small subunit	84
649929426	576	33.94	1	574	5	581	1.0e-98	354	COG2414	Aldehyde:ferredoxin oxidoreductase	614
649929427	412	51.59	35	412	4	377	9.0e-126	443	COG1454	Alcohol dehydrogenase, class IV	377
649929428	326	43.56	3	326	2	322	6.0e-95	341	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
649929431	270	45.83	1	262	2	253	3.0e-62	232	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
649929432	448	49.85	108	432	1	312	1.0e-96	347	COG2025	Electron transfer flavoprotein, alpha subunit	313
649929433	658	28.36	263	656	1	387	8.0e-65	242	COG0247	Fe-S oxidoreductase	388
649929436	447	29.29	16	302	32	327	9.0e-36	144	COG3344	Retron-type reverse transcriptase	328
649929439	390	21.2	49	389	53	388	4.0e-26	112	COG3864	Predicted metal-dependent peptidase	396
649929440	353	20.76	23	304	48	318	8.0e-04	38.6	COG0714	MoxR-like ATPase	329
649929441	104	29	4	103	11	106	4.0e-04	36.5	COG4980	Gas vesicle protein	115
649929442	63	31.75	7	63	5	67	9.0e-06	41.9	COG1141	Ferredoxin	68
649929445	396	29.72	178	382	18	227	1.0e-28	120	COG1969	Ni,Fe-hydrogenase I cytochrome b subunit	227
649929446	571	49.82	5	571	3	545	0.0e+00	598	COG0374	Ni,Fe-hydrogenase I large subunit	545
649929447	392	48.21	13	372	2	355	3.0e-107	382	COG1740	Ni,Fe-hydrogenase I small subunit	355
649929449	492	36.31	62	229	54	217	9.0e-32	131	COG3786	L,D-peptidoglycan transpeptidase YkuD, ErfK/YbiS/YcfS/YnhG family	217
649929450	251	23.4	1	215	12	242	4.0e-10	58.5	COG0226	ABC-type phosphate transport system, periplasmic component	318
649929451	836	33.9	417	826	2	407	1.0e-49	191	COG0840	Methyl-accepting chemotaxis protein	408
649929452	92	24.72	1	87	1	88	1.0e-02	31.8	COG2747	Negative regulator of flagellin synthesis (anti-sigma28 factor)	93
649929454	331	43.75	1	317	1	316	4.0e-88	318	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649929455	691	60.91	11	688	3	661	0.0e+00	975	COG0021	Transketolase	663
649929457	179	22.36	20	179	23	167	2.0e-04	38.7	COG1818	tRNA(Ser,Leu) C12 N-acetylase TAN1, contains THUMP domain	175
649929458	198	37.8	6	168	4	160	8.0e-36	143	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
649929463	470	39.26	8	466	4	452	3.0e-104	372	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649929464	572	27.8	1	249	11	269	1.0e-28	122	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
649929465	632	35.83	273	632	55	408	9.0e-54	205	COG0840	Methyl-accepting chemotaxis protein	408
649929470	619	51.3	9	619	1	594	0.0e+00	636	COG0465	ATP-dependent Zn proteases	596
649929472	84	42.68	1	80	3	84	3.0e-09	53.9	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
649929473	84	48.81	1	84	1	84	2.0e-25	106	COG4115	Toxin component of the Txe-Axe toxin-antitoxin module, Txe/YoeB family	84
649929476	203	47.12	3	203	4	207	3.0e-54	205	COG4832	Uncharacterized protein	207
649929480	100	39.76	4	85	2	84	1.0e-17	81.1	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
649929482	105	30.69	3	99	2	102	1.0e-10	58.4	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
649929484	110	30.88	34	98	1	68	2.0e-10	57.7	COG0695	Glutaredoxin	80
649929486	1038	35.06	692	978	81	408	2.0e-46	181	COG0840	Methyl-accepting chemotaxis protein	408
649929487	350	46.15	12	341	5	340	3.0e-95	342	COG1816	Adenosine deaminase	345
649929490	139	25.23	13	119	2	106	1.0e-13	69	COG0789	DNA-binding transcriptional regulator, MerR family	124
649929492	101	28.12	7	101	6	101	2.0e-09	54.1	COG3162	Uncharacterized membrane protein, DUF485 family	102
649929493	660	39.26	74	651	3	528	6.0e-110	391	COG4147	Na+(or H+)/acetate symporter ActP	529
649929495	1082	33.7	152	423	3	271	1.0e-66	248	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
649929495	1082	38.97	511	1082	1	548	0.0e+00	534	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
649929496	177	31.4	1	173	3	207	3.0e-24	105	COG0778	Nitroreductase	207
649929497	388	29.13	1	388	4	383	2.0e-50	193	COG0006	Xaa-Pro aminopeptidase	384
649929498	391	42.61	1	391	1	392	3.0e-75	276	COG0183	Acetyl-CoA acetyltransferase	392
649929499	281	50	1	281	2	283	5.0e-93	334	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
649929500	260	46.72	1	257	2	257	8.0e-59	220	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
649929501	379	48.32	1	378	1	387	4.0e-107	381	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
649929502	706	27.85	282	657	1	387	2.0e-60	227	COG0247	Fe-S oxidoreductase	388
649929503	258	38.93	1	257	1	260	2.0e-57	216	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
649929504	305	36.62	1	301	1	308	2.0e-65	242	COG2025	Electron transfer flavoprotein, alpha subunit	313
649929508	539	35.54	132	539	6	408	8.0e-46	178	COG0840	Methyl-accepting chemotaxis protein	408
649929512	251	40.93	3	239	65	294	5.0e-54	204	COG4302	Ethanolamine ammonia-lyase, small subunit	294
649929513	465	58.63	1	451	1	451	0.0e+00	677	COG4303	Ethanolamine ammonia-lyase, large subunit	453
649929518	384	21.84	4	376	7	384	4.0e-21	95.8	COG4872	Uncharacterized membrane protein	394
649929519	576	35.45	1	557	5	569	7.0e-100	358	COG2414	Aldehyde:ferredoxin oxidoreductase	614
649929520	342	35.47	1	331	7	318	8.0e-58	217	COG0226	ABC-type phosphate transport system, periplasmic component	318
649929521	108	42.06	1	107	1	107	1.0e-30	125	COG4226	Predicted nuclease of the RNAse H fold, HicB family	111
649929522	199	33.68	3	190	2	188	5.0e-23	101	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
649929523	555	31.25	191	527	9	360	2.0e-49	190	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
649929528	311	32.79	1	306	4	293	6.0e-57	214	COG1131	ABC-type multidrug transport system, ATPase component	293
649929529	408	31.96	62	370	14	353	8.0e-46	178	COG2108	Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme	353
649929530	161	52.94	5	155	4	151	3.0e-55	207	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
649929531	3054	42.11	1965	3051	2	1054	0.0e+00	930	COG3459	Cellobiose phosphorylase	1056
649929534	359	45.45	1	359	3	361	2.0e-100	359	COG4748	Uncharacterized protein	365
649929538	449	19.34	139	367	30	292	2.0e-09	57.6	COG0501	Zn-dependent protease with chaperone function	302
649929540	109	24.73	6	98	3	95	5.0e-05	39.8	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
649929542	104	37	1	98	1	98	1.0e-15	75	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
649929544	80	37.31	1	66	8	74	3.0e-12	63.5	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
649929545	281	60.07	3	279	1	278	6.0e-110	390	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
649929546	288	57.99	1	287	2	289	1.0e-120	426	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
649929547	286	19.52	14	264	11	228	9.0e-09	54.4	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
649929548	270	44.44	1	268	2	259	1.0e-61	230	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
649929549	441	48.92	109	433	1	312	2.0e-96	346	COG2025	Electron transfer flavoprotein, alpha subunit	313
649929550	664	28.82	267	657	1	383	1.0e-64	241	COG0247	Fe-S oxidoreductase	388
649929552	228	37.57	1	186	2	185	2.0e-32	132	COG0518	GMP synthase - Glutamine amidotransferase domain	198
649929553	823	31.59	70	413	1	336	1.0e-44	175	COG0642	Signal transduction histidine kinase	336
649929555	112	66.07	1	112	1	112	3.0e-37	146	COG0347	Nitrogen regulatory protein PII	112
649929556	515	55.08	97	515	1	403	1.0e-122	433	COG0004	Ammonia channel protein AmtB	409
649929558	270	46.67	11	260	5	259	2.0e-65	242	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
649929559	151	37.18	1	151	1	152	2.0e-17	81.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649929560	264	22.58	1	257	3	274	2.0e-20	92.6	COG1082	Sugar phosphate isomerase/epimerase	274
649929562	505	32.76	2	500	5	523	3.0e-88	319	COG4147	Na+(or H+)/acetate symporter ActP	529
649929563	107	18.68	15	105	9	90	3.0e-08	50.4	COG4327	Uncharacterized membrane protein	101
649929565	665	39.63	83	657	8	529	5.0e-111	395	COG4147	Na+(or H+)/acetate symporter ActP	529
649929566	103	30.21	7	101	5	100	3.0e-12	63.3	COG3162	Uncharacterized membrane protein, DUF485 family	102
649929570	460	43.51	1	458	2	461	0.0e+00	479	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649929571	656	27.62	318	654	7	333	3.0e-44	173	COG0642	Signal transduction histidine kinase	336
649929572	299	27.74	12	293	5	293	2.0e-40	159	COG4866	Uncharacterized protein	294
649929573	343	28.31	2	331	4	324	3.0e-34	139	COG2603	tRNA 2-selenouridine synthase SelU, contains rhodanese domain	334
649929575	391	53.06	1	391	15	404	0.0e+00	461	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
649929577	392	30.81	9	380	1	390	4.0e-41	162	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649929579	888	59.26	6	886	1	877	0.0e+00	1244	COG0525	Valyl-tRNA synthetase	877
649929580	274	39.93	7	274	2	254	3.0e-29	122	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
649929581	490	31.43	142	486	16	331	5.0e-42	166	COG0642	Signal transduction histidine kinase	336
649929582	456	47.28	1	456	1	457	0.0e+00	477	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649929583	263	19.14	86	261	34	239	1.0e-09	57.1	COG1651	Protein-disulfide isomerase	244
649929584	1645	20	631	1575	160	961	1.0e-21	99.7	COG3419	Tfp pilus assembly protein, tip-associated adhesin PilY1	1036
649929587	392	20.92	1	153	3	142	2.0e-04	40.4	COG2165	Type II secretory pathway, pseudopilin PulG	149
649929591	386	23.02	1	126	1	116	1.0e-04	41.2	COG2165	Type II secretory pathway, pseudopilin PulG	149
649929593	82	37.29	18	75	1	59	5.0e-05	39.4	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
649929594	350	38	2	345	4	351	1.0e-73	270	COG4972	Tfp pilus assembly protein, ATPase PilM	354
649929595	182	24.18	1	182	4	182	3.0e-12	65	COG3166	Tfp pilus assembly protein PilN	206
649929596	201	35.36	17	197	27	204	1.0e-32	133	COG3167	Tfp pilus assembly protein PilO	211
649929597	184	26.63	12	180	6	166	6.0e-06	44.2	COG3168	Tfp pilus assembly protein PilP	170
649929598	922	26.29	254	921	1	707	8.0e-65	242	COG4796	Type II secretory pathway, component HofQ	709
649929602	393	47.55	1	386	8	368	4.0e-120	424	COG0082	Chorismate synthase	369
649929603	172	36.9	5	172	3	170	4.0e-44	170	COG0703	Shikimate kinase	172
649929604	362	56.29	3	350	1	347	8.0e-118	417	COG0337	3-dehydroquinate synthetase	360
649929606	120	22.73	3	112	5	112	3.0e-06	44	COG2018	Predicted regulator of Ras-like GTPase activity, Roadblock/LC7/MglB family	119
649929607	149	65.03	7	149	2	144	3.0e-56	210	COG0757	3-dehydroquinate dehydratase	146
649929608	355	39.47	1	355	9	383	4.0e-80	291	COG0006	Xaa-Pro aminopeptidase	384
649929609	158	42.11	6	157	1	140	3.0e-24	104	COG0511	Biotin carboxyl carrier protein	140
649929611	129	48.41	1	124	3	128	8.0e-35	139	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
649929612	273	35.32	1	268	1	252	2.0e-37	149	COG1427	Predicted periplasmic solute-binding protein	252
649929614	474	32.91	1	470	5	457	7.0e-92	331	COG1109	Phosphomannomutase	464
649929615	286	42.28	1	129	3	149	2.0e-29	123	COG0822	NifU homolog involved in Fe-S cluster formation	150
649929616	389	54.97	4	382	3	384	0.0e+00	513	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
649929617	485	44.58	238	475	11	249	3.0e-65	243	COG1119	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA	257
649929618	1492	36.52	3	836	2	786	0.0e+00	647	COG1201	Lhr-like helicase	814
649929621	252	21.58	1	252	2	291	1.0e-17	83.6	COG1234	Ribonuclease BN, tRNA processing enzyme	292
649929624	143	48.85	13	143	12	141	4.0e-34	136	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
649929625	663	33.23	21	659	3	650	0.0e+00	467	COG0370	Fe2+ transport system protein B	653
649929627	214	31.01	1	153	2	153	5.0e-16	78.1	COG1321	Mn-dependent transcriptional regulator, DtxR family	154
649929628	599	19.23	205	539	64	396	9.0e-09	55.8	COG0840	Methyl-accepting chemotaxis protein	408
649929631	694	37.11	1	692	5	712	0.0e+00	564	COG0643	Chemotaxis protein histidine kinase CheA	716
649929632	292	45.39	24	290	2	265	2.0e-71	262	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
649929633	165	32.3	1	160	1	158	2.0e-28	118	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
649929634	355	48.3	4	354	1	343	4.0e-100	358	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
649929635	411	31.94	6	407	3	403	2.0e-69	256	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
649929636	251	51.76	1	251	2	244	2.0e-79	289	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
649929637	533	65.91	3	532	1	530	0.0e+00	886	COG0504	CTP synthase (UTP-ammonia lyase)	533
649929638	274	63.6	1	272	1	272	5.0e-121	427	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
649929639	321	61.88	2	202	1	202	1.0e-64	240	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
649929640	171	53.25	1	169	1	169	1.0e-57	215	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
649929641	429	38.48	3	427	7	436	1.0e-114	406	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
649929642	899	33.7	203	378	41	220	2.0e-23	104	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
649929643	393	19.87	8	369	7	450	4.0e-13	69.3	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
649929644	429	37.88	5	427	9	436	2.0e-114	406	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
649929645	343	37.2	20	341	4	314	2.0e-53	203	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649929647	217	29.63	25	150	39	173	6.0e-13	68	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
649929648	366	43.56	6	359	3	365	5.0e-110	391	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649929649	327	33.13	10	326	2	313	4.0e-51	195	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649929650	383	46.28	8	382	6	370	5.0e-108	384	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649929651	626	33.67	1	598	1	519	6.0e-101	362	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
649929652	325	21.91	34	205	6	173	2.0e-11	63.4	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
649929653	180	26.28	32	167	38	174	6.0e-15	74.2	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
649929655	201	48.24	1	198	3	199	9.0e-69	253	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
649929656	252	42.17	1	246	1	249	1.0e-72	266	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
649929658	481	19.22	5	461	4	463	6.0e-15	75.9	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
649929659	363	15.83	17	363	29	379	3.0e-07	49.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929661	356	22.19	60	352	17	318	2.0e-16	80	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649929662	396	26.35	68	396	55	380	9.0e-20	91.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929664	501	21.8	1	467	4	474	3.0e-18	87.1	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
649929667	654	29.19	1	623	1	519	5.0e-99	355	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
649929668	374	25.83	20	368	23	374	1.0e-34	141	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929669	197	47.22	1	175	40	219	1.0e-55	209	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
649929671	404	43.31	16	396	7	371	2.0e-110	393	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649929672	382	27.64	22	380	22	381	5.0e-35	142	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929673	320	31.79	4	319	3	312	3.0e-40	158	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649929674	213	44.62	28	211	40	225	4.0e-54	204	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
649929675	656	44.61	8	607	1	581	0.0e+00	605	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
649929677	648	44.11	8	607	1	581	0.0e+00	599	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
649929681	294	34.9	4	258	9	262	5.0e-44	171	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
649929686	432	37.3	1	430	1	437	2.0e-115	409	COG0621	tRNA A37 methylthiotransferase MiaB	437
649929687	222	54.12	1	194	3	194	6.0e-71	260	COG1045	Serine acetyltransferase	194
649929688	316	33.77	14	306	4	304	1.0e-62	233	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
649929689	458	44.35	5	369	6	369	1.0e-95	343	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
649929690	196	41.54	8	196	6	200	1.0e-46	179	COG2928	Uncharacterized membrane protein	222
649929691	325	41.41	1	318	1	322	8.0e-79	287	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
649929692	586	33.57	168	584	32	451	3.0e-73	270	COG5002	Signal transduction histidine kinase	459
649929693	226	49.56	4	226	3	228	4.0e-61	227	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649929694	549	38.81	1	547	5	533	0.0e+00	487	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
649929695	396	29.8	1	387	2	374	1.0e-48	187	COG0006	Xaa-Pro aminopeptidase	384
649929696	441	30.73	41	432	18	382	1.0e-72	267	COG0372	Citrate synthase	390
649929697	182	39.47	1	181	1	190	4.0e-39	154	COG2078	Uncharacterized conserved protein, AMMECR1 domain	203
649929698	137	56.82	1	132	2	133	1.0e-50	191	COG0105	Nucleoside diphosphate kinase	135
649929699	344	49.42	3	336	1	342	2.0e-113	402	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
649929700	287	42.34	6	248	19	262	1.0e-64	240	COG0005	Purine nucleoside phosphorylase	262
649929701	305	22.96	2	292	1	309	7.0e-19	88.3	COG0524	Sugar or nucleoside kinase, ribokinase family	311
649929705	147	36	1	145	2	151	1.0e-19	89.3	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649929708	526	34.79	7	523	2	486	8.0e-101	361	COG2509	Uncharacterized FAD-dependent dehydrogenase	486
649929709	385	35.53	14	286	1	265	2.0e-43	169	COG3481	3'-5' exoribonuclease YhaM, can participate in 23S rRNA maturation,  HD superfamily	287
649929710	209	37.09	1	205	12	224	3.0e-34	138	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
649929711	401	54.62	1	389	1	385	4.0e-114	405	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
649929713	198	26.35	63	197	36	202	2.0e-07	49.2	COG1573	Uracil-DNA glycosylase	202
649929715	399	24.4	21	374	6	380	2.0e-23	103	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929716	270	44.88	10	136	2	128	5.0e-29	121	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
649929716	270	50.72	130	198	1	69	2.0e-15	76.9	COG3585	Molybdopterin-binding protein	69
649929717	288	48.24	1	283	1	277	3.0e-81	295	COG2998	ABC-type tungstate transport system, permease component	280
649929718	232	38.77	2	228	1	227	5.0e-42	164	COG4662	ABC-type tungstate transport system, periplasmic component	227
649929719	366	34.07	3	363	1	352	8.0e-72	264	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
649929721	189	42.78	1	185	1	187	5.0e-38	150	COG1971	Putative Mn2+ efflux pump MntP	190
649929723	325	35.91	3	325	9	322	2.0e-70	259	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
649929724	539	31.51	31	504	4	460	1.0e-81	297	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
649929725	139	40.97	4	128	6	149	1.0e-19	89.3	COG0822	NifU homolog involved in Fe-S cluster formation	150
649929726	347	52.62	1	344	1	335	1.0e-93	336	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
649929727	139	38.3	2	135	1	139	2.0e-35	141	COG0394	Protein-tyrosine-phosphatase	139
649929729	342	35.65	1	331	6	318	2.0e-56	213	COG0226	ABC-type phosphate transport system, periplasmic component	318
649929730	285	29.73	149	280	5	152	4.0e-11	62.3	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649929731	223	40.37	5	221	8	225	4.0e-39	154	COG0704	Phosphate uptake regulator	240
649929732	252	69.2	3	252	6	253	5.0e-123	433	COG1117	ABC-type phosphate transport system, ATPase component	253
649929733	280	43.16	4	280	8	291	2.0e-61	229	COG0581	ABC-type phosphate transport system, permease component	292
649929734	337	45.57	31	330	12	308	6.0e-73	267	COG0573	ABC-type phosphate transport system, permease component	310
649929736	583	31.99	165	580	29	446	2.0e-69	257	COG5002	Signal transduction histidine kinase	459
649929737	227	49.12	4	226	3	226	5.0e-65	241	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649929738	350	33.53	10	335	22	317	4.0e-50	192	COG0226	ABC-type phosphate transport system, periplasmic component	318
649929739	223	39.64	1	221	4	225	4.0e-39	154	COG0704	Phosphate uptake regulator	240
649929745	399	29.23	133	392	103	362	2.0e-39	156	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
649929748	335	25.28	41	304	2	232	1.0e-20	94.2	COG0688	Phosphatidylserine decarboxylase	239
649929754	382	32.46	43	376	8	341	3.0e-38	152	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649929759	140	27.93	1	110	1	108	6.0e-03	33.7	COG2105	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family	120
649929760	230	35.43	1	221	1	214	3.0e-34	138	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
649929761	518	40.87	4	462	3	451	4.0e-105	375	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
649929763	730	22.9	165	547	135	508	4.0e-09	57.3	COG1404	Serine protease, subtilisin family	508
649929766	171	26.04	1	167	2	169	6.0e-07	47.3	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
649929774	670	26.67	332	476	6	148	4.0e-13	70.3	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
649929775	554	27.01	37	554	48	554	3.0e-60	226	COG2831	Hemolysin activation/secretion protein	554
649929777	598	26.29	384	596	7	215	2.0e-24	107	COG0811	Biopolymer transport protein ExbB/TolQ	216
649929778	135	37.1	9	132	11	134	3.0e-23	100	COG0848	Biopolymer transport protein ExbD	137
649929779	242	22.61	9	238	26	237	7.0e-07	47.8	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
649929781	261	15.71	52	260	39	240	1.0e-10	60.6	COG1651	Protein-disulfide isomerase	244
649929786	494	22.15	12	480	4	477	1.0e-17	85.2	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
649929787	435	24.94	4	432	3	443	3.0e-49	189	COG1232	Protoporphyrinogen oxidase	444
649929790	317	32.1	5	273	3	273	2.0e-44	173	COG1216	Glycosyltransferase, GT2 family	305
649929791	372	19.59	25	359	52	381	4.0e-14	72.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929795	398	26.59	52	393	53	381	1.0e-21	97.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929796	714	32.64	399	714	6	340	1.0e-45	178	COG0673	Predicted dehydrogenase	342
649929798	263	43.15	1	245	6	251	2.0e-58	219	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
649929800	542	32.18	1	307	3	314	1.0e-40	161	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
649929801	660	23.57	192	498	62	340	1.0e-09	58.8	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
649929802	256	35.63	88	256	35	204	6.0e-24	104	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
649929804	521	18.86	1	450	7	458	1.0e-26	114	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
649929805	322	27.88	100	321	6	228	4.0e-25	109	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
649929806	402	56.69	1	378	3	373	0.0e+00	482	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
649929807	416	49.06	8	416	12	424	0.0e+00	474	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
649929812	340	23.21	58	325	1	277	8.0e-14	71.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649929813	562	33.61	1	548	9	592	6.0e-110	391	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
649929814	717	49.85	23	698	5	682	0.0e+00	742	COG0855	Polyphosphate kinase	696
649929815	273	24.44	8	272	62	326	1.0e-27	116	COG1723	Uncharacterized protein, Rmd1/YagE family	331
649929818	185	38.5	5	185	4	203	4.0e-26	111	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
649929824	428	27.5	178	408	57	281	6.0e-09	55.6	COG4974	Site-specific recombinase XerD	300
649929828	425	36.67	182	419	20	228	1.0e-46	180	COG0860	N-acetylmuramoyl-L-alanine amidase	231
649929829	869	49.71	1	866	3	842	0.0e+00	934	COG0249	DNA mismatch repair ATPase MutS	843
649929830	428	37.85	6	423	11	433	2.0e-110	393	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
649929832	409	43.54	5	353	1	354	3.0e-89	322	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
649929834	201	45.32	1	201	1	201	3.0e-46	178	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
649929836	285	22.52	2	285	3	282	3.0e-23	102	COG3016	Uncharacterized iron-regulated protein	295
649929842	360	22.12	8	325	33	347	8.0e-10	58.4	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
649929844	387	21.69	28	351	41	358	6.0e-13	68.8	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
649929846	881	24.14	6	220	8	234	2.0e-12	68.8	COG3063	Tfp pilus assembly protein PilF	250
649929847	459	46.49	232	458	1	224	2.0e-62	233	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
649929848	267	33.5	19	211	41	239	2.0e-19	89.4	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
649929849	496	20.22	3	416	11	458	2.0e-28	120	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
649929850	290	37.07	69	270	29	230	2.0e-31	129	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
649929851	387	35.36	1	261	9	269	1.0e-37	151	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
649929855	397	28.73	34	395	37	370	9.0e-42	164	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649929858	608	27.07	12	585	148	696	8.0e-79	288	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
649929860	410	23.03	94	396	77	372	9.0e-22	98.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929861	388	22.05	9	377	4	377	2.0e-25	110	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929862	413	22.19	23	353	10	336	4.0e-24	106	COG3919	Predicted ATP-dependent carboligase, ATP-grasp superfamily	415
649929863	375	27.58	1	372	2	379	7.0e-34	138	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929864	435	15.08	8	394	9	396	2.0e-06	47.1	COG3307	O-antigen ligase	424
649929865	183	31.43	40	176	4	136	5.0e-22	97.6	COG0394	Protein-tyrosine-phosphatase	139
649929866	331	19.44	25	324	64	381	1.0e-05	44.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929868	375	21.37	14	375	8	378	2.0e-30	127	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929871	364	25.46	1	364	2	380	1.0e-35	144	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649929872	376	21.86	1	372	9	404	3.0e-19	90	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
649929873	200	22.75	3	187	30	195	2.0e-05	42.9	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
649929877	241	26.98	15	229	1	213	5.0e-33	134	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
649929878	690	24.76	392	683	34	335	1.0e-23	105	COG0642	Signal transduction histidine kinase	336
649929879	452	46.52	1	451	4	457	0.0e+00	483	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649929880	527	34.85	1	518	11	533	1.0e-99	357	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
649929881	82	29.63	1	81	3	80	4.0e-04	36.4	COG0236	Acyl carrier protein	80
649929882	328	30.35	9	316	1	259	9.0e-57	213	COG0171	NH3-dependent NAD+ synthetase	268
649929883	660	30.05	1	596	1	509	9.0e-108	384	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
649929884	213	21.77	56	182	3	139	4.0e-06	44.9	COG1247	L-amino acid N-acyltransferase YncA	169
649929886	161	28.26	7	143	32	169	4.0e-10	57.7	COG1633	Rubrerythrin	176
649929887	486	35.26	307	468	1	173	1.0e-31	131	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649929891	107	27.55	1	97	3	100	1.0e-10	58.4	COG1359	Quinol monooxygenase YgiN	100
649929892	153	37.78	1	135	2	131	5.0e-33	133	COG1959	DNA-binding transcriptional regulator, IscR family	150
649929893	332	73.41	8	332	18	348	0.0e+00	527	COG1613	ABC-type sulfate transport system, periplasmic component	348
649929895	275	33.71	6	250	4	263	3.0e-28	118	COG1348	Nitrogenase subunit NifH, an ATPase	278
649929896	276	55.88	5	276	3	274	6.0e-75	274	COG0555	ABC-type sulfate transport system, permease component	274
649929897	288	66.19	5	285	5	285	1.0e-108	386	COG4208	ABC-type sulfate transport system, permease component	287
649929898	355	58.81	1	349	1	342	2.0e-114	405	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
649929899	135	31.82	25	90	8	73	7.0e-09	53.1	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
649929902	196	37.63	6	196	9	190	1.0e-21	96.2	COG0558	Phosphatidylglycerophosphate synthase	192
649929904	531	48.86	1	527	4	509	0.0e+00	605	COG0029	Aspartate oxidase	518
649929905	91	37.21	1	84	8	93	2.0e-10	57.7	COG1605	Chorismate mutase	101
649929907	894	34.37	28	893	16	862	0.0e+00	633	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
649929908	292	54.05	1	292	5	300	4.0e-101	361	COG4974	Site-specific recombinase XerD	300
649929909	399	43	1	398	4	404	2.0e-107	383	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archeal type	408
649929910	434	21.36	37	426	18	385	4.0e-32	132	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
649929912	221	28.48	21	176	2	152	2.0e-12	65.8	COG0681	Signal peptidase I	166
649929913	599	69.78	1	599	4	602	0.0e+00	1037	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
649929914	547	34.99	144	546	9	408	7.0e-52	198	COG0840	Methyl-accepting chemotaxis protein	408
649929915	369	37.91	20	368	70	406	2.0e-66	246	COG1915	Uncharacterized conserved protein, contains Saccharopine dehydrogenase N-terminal (SDHN) domain	415
649929916	296	36.54	1	296	20	303	1.0e-48	186	COG0010	Arginase family enzyme	305
649929917	224	53.85	5	223	1	221	2.0e-76	278	COG1136	ABC-type lipoprotein export system, ATPase component	226
649929918	386	24.23	1	386	3	408	4.0e-33	135	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649929921	180	29.29	1	177	1	196	9.0e-28	116	COG0288	Carbonic anhydrase	207
649929922	749	58.31	7	430	21	432	0.0e+00	552	COG0281	Malic enzyme	432
649929923	187	22.22	6	112	2	109	3.0e-07	48.5	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
649929925	163	56.69	4	160	3	159	3.0e-56	211	COG0669	Phosphopantetheine adenylyltransferase	159
649929926	193	39.46	1	183	2	183	2.0e-43	168	COG0742	16S rRNA G966 N2-methylase RsmD	187
649929927	382	40.25	15	378	12	411	3.0e-98	352	COG0232	dGTP triphosphohydrolase	412
649929928	135	30.65	4	125	3	125	8.0e-19	86.2	COG2703	Hemerythrin	144
649929929	98	49.48	1	97	1	97	4.0e-24	102	COG1534	RNA-binding protein YhbY	97
649929930	177	61.39	6	162	5	162	2.0e-55	208	COG2065	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	179
649929931	310	49.52	1	307	3	314	3.0e-105	374	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
649929932	424	48	1	424	1	422	3.0e-130	458	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
649929933	374	57.6	1	373	2	366	0.0e+00	548	COG0505	Carbamoylphosphate synthase small subunit	368
649929934	303	42.72	2	299	52	335	7.0e-77	280	COG1313	Uncharacterized Fe-S protein PflX, radical SAM superfamily	335
649929935	1082	69.52	13	409	1	395	0.0e+00	562	COG0458	Carbamoylphosphate synthase large subunit	400
649929936	158	51.32	7	158	1	151	6.0e-39	153	COG0782	Transcription elongation factor, GreA/GreB family	151
649929938	769	52.15	71	742	10	664	0.0e+00	794	COG1200	RecG-like helicase	677
649929941	256	35.06	9	255	1	249	4.0e-53	201	COG1135	ABC-type methionine transport system, ATPase component	339
649929942	263	41.57	4	258	1	252	1.0e-59	223	COG0390	ABC-type iron transport system FetAB, permease component	256
649929943	350	41.76	13	348	3	339	3.0e-107	381	COG2008	Threonine aldolase	342
649929944	304	21.75	1	281	3	287	6.0e-05	42.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
649929945	247	34.23	1	244	3	262	4.0e-32	131	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
649929946	261	45.5	51	259	10	220	9.0e-54	203	COG0765	ABC-type amino acid transport system, permease component	222
649929947	248	68.75	9	248	2	240	1.0e-111	396	COG1126	ABC-type polar amino acid transport system, ATPase component	240
649929949	397	37.99	33	385	1	356	3.0e-55	209	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
649929950	286	34.39	7	283	33	297	3.0e-42	165	COG0501	Zn-dependent protease with chaperone function	302
649929951	250	49.39	1	242	8	254	2.0e-54	205	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
649929952	896	39.98	6	891	6	880	0.0e+00	739	COG1615	Uncharacterized membrane protein, UPF0182 family	885
649929953	94	48.42	1	94	2	88	8.0e-19	85.4	COG3809	Predicted nucleic acid-binding protein, contains Zn-finger domain	88
649929954	431	23.27	30	422	41	442	2.0e-28	120	COG1538	Outer membrane protein TolC	457
649929955	413	35.58	80	401	41	361	2.0e-24	106	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649929956	1034	47.43	1	1029	1	1022	0.0e+00	1096	COG3696	Cu/Ag efflux pump CusA	1027
649929957	291	47.46	1	290	5	297	1.0e-49	190	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
649929958	300	40.69	5	280	17	306	1.0e-45	176	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
649929959	257	55.34	1	252	2	250	7.0e-93	333	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
649929960	233	59.4	1	232	3	236	2.0e-94	338	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
649929961	306	27.6	13	290	11	287	3.0e-08	52.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
649929962	160	35.07	24	156	18	150	6.0e-22	96.9	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
649929963	455	43.11	7	455	2	436	1.0e-94	340	COG0733	Na+-dependent transporter, SNF family	439
649929964	303	51.72	13	302	2	290	7.0e-74	270	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
649929965	91	20	3	91	2	91	8.0e-06	42.2	COG3041	mRNA-degrading endonuclease (mRNA interferase) YafQ, toxin component of the YafQ-DinJ toxin-antitoxin module	91
649929967	481	43.97	13	481	100	560	6.0e-117	414	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
649929968	1004	38.41	510	988	1	469	5.0e-121	429	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
649929969	326	43.81	19	314	14	326	9.0e-82	297	COG0158	Fructose-1,6-bisphosphatase	326
649929971	484	43.6	1	484	3	462	0.0e+00	460	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649929972	347	37.46	4	337	16	350	2.0e-73	269	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
649929975	94	44.05	9	92	8	91	2.0e-20	90.7	COG2257	Type III secretion system substrate exporter, FlhB-like	92
649929976	292	24.83	13	288	1	277	7.0e-25	108	COG3016	Uncharacterized iron-regulated protein	295
649929977	204	56.5	5	204	1	200	1.0e-76	279	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
649929978	348	63.19	5	348	3	345	0.0e+00	478	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
649929979	160	40	1	147	5	169	4.0e-21	94.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
649929980	269	33.33	7	268	12	252	2.0e-40	159	COG0543	NAD(P)H-flavin reductase	252
649929981	305	40.58	5	303	1	307	6.0e-74	270	COG0167	Dihydroorotate dehydrogenase	310
649929982	343	49.71	4	343	16	365	2.0e-108	385	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
649929983	302	27.76	1	296	1	291	6.0e-33	134	COG0583	DNA-binding transcriptional regulator, LysR family	297
649929985	130	36.36	11	120	8	112	3.0e-10	57.3	COG1734	RNA polymerase-binding transcription factor DksA	120
649929986	362	23.44	1	189	1	185	2.0e-16	80.3	COG0132	Dethiobiotin synthetase	223
649929989	447	23.64	91	391	15	329	7.0e-32	132	COG0641	Sulfatase maturation enzyme AslB, radical SAM superfamily	378
649929991	606	22.26	21	606	10	608	1.0e-33	138	COG4206	Outer membrane cobalamin receptor protein	608
649929992	282	21.57	2	278	9	309	2.0e-15	76.1	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
649929996	356	43.71	2	346	1	349	1.0e-85	309	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
649929998	578	31.55	203	576	46	405	4.0e-40	159	COG0840	Methyl-accepting chemotaxis protein	408
649929999	181	33.33	28	177	9	158	8.0e-26	110	COG0835	Chemotaxis signal transduction protein	165
649930000	635	40	136	400	7	268	3.0e-63	236	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
649930001	368	39.73	1	359	4	369	1.0e-87	317	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
649930004	557	40.92	5	433	1	415	2.0e-58	220	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
649930006	173	30.69	1	167	5	201	9.0e-18	83.1	COG0778	Nitroreductase	207
649930007	196	20.92	1	196	2	195	1.0e-12	66.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649930008	426	37.87	14	382	13	372	5.0e-30	125	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649930009	1053	52.32	1	1033	2	1009	0.0e+00	1009	COG0841	Multidrug efflux pump subunit AcrB	1009
649930010	473	40.83	14	471	1	445	3.0e-72	266	COG1538	Outer membrane protein TolC	457
649930011	326	31.86	11	324	7	318	2.0e-50	193	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
649930013	281	38.31	73	272	31	227	1.0e-50	193	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
649930017	476	38.39	15	472	1	449	6.0e-55	208	COG1538	Outer membrane protein TolC	457
649930018	430	25.33	83	340	52	351	6.0e-22	98.9	COG1566	Multidrug resistance efflux pump	352
649930019	234	52.21	6	230	1	226	6.0e-80	290	COG1136	ABC-type lipoprotein export system, ATPase component	226
649930020	400	31.5	18	400	2	419	1.0e-37	151	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649930021	447	29.24	2	444	11	452	2.0e-42	166	COG0534	Na+-driven multidrug efflux pump	455
649930022	230	42.15	10	229	24	242	2.0e-50	192	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
649930023	301	35.71	2	301	13	261	3.0e-58	219	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
649930024	550	63.88	19	436	1	418	0.0e+00	658	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
649930029	333	41.05	1	320	1	315	3.0e-87	315	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649930030	241	28.21	57	206	13	155	2.0e-16	79.7	COG0437	Fe-S-cluster-containing dehydrogenase component	203
649930031	601	40.03	6	597	3	609	0.0e+00	495	COG2414	Aldehyde:ferredoxin oxidoreductase	614
649930032	352	39.32	1	348	1	339	2.0e-104	372	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
649930036	111	34.38	1	95	3	98	3.0e-06	43.6	COG0640	DNA-binding transcriptional regulator, ArsR family	110
649930037	222	37.56	28	218	3	198	2.0e-41	162	COG0437	Fe-S-cluster-containing dehydrogenase component	203
649930039	292	29.24	1	286	1	296	7.0e-36	144	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
649930041	460	49.24	1	456	4	462	0.0e+00	503	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649930042	222	39.09	28	218	3	198	1.0e-41	163	COG0437	Fe-S-cluster-containing dehydrogenase component	203
649930045	226	32.71	116	218	3	107	5.0e-10	58	COG0607	Rhodanese-related sulfurtransferase	110
649930046	382	51.06	4	377	2	379	2.0e-127	449	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
649930052	657	36.07	11	649	10	604	5.0e-128	452	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
649930053	576	33.72	1	573	5	587	3.0e-97	349	COG2414	Aldehyde:ferredoxin oxidoreductase	614
649930054	408	20.44	8	398	2	398	3.0e-43	169	COG1160	Predicted GTPases	444
649930055	469	50.11	1	469	1	471	0.0e+00	564	COG1027	Aspartate ammonia-lyase	471
649930056	474	22.31	34	398	6	367	7.0e-58	218	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
649930057	346	29.43	2	294	15	294	3.0e-45	176	COG0502	Biotin synthase or related enzyme	335
649930059	284	31.91	6	280	11	307	8.0e-28	117	COG0650	Formate hydrogenlyase subunit 4	309
649930060	164	54.35	12	149	7	144	2.0e-48	185	COG3260	Ni,Fe-hydrogenase III small subunit	148
649930062	358	42.62	4	358	9	367	8.0e-97	347	COG3261	Ni,Fe-hydrogenase III large subunit	382
649930063	125	33.33	4	117	19	140	5.0e-18	83.5	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
649930064	130	35.09	1	114	1	114	3.0e-21	93.8	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
649930065	218	34.48	11	209	1	196	2.0e-43	168	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
649930066	173	37.58	17	173	1	157	1.0e-40	159	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
649930067	123	25.45	59	113	1	52	7.0e-04	36.1	COG3411	(2Fe-2S) ferredoxin	64
649930068	489	55.85	4	422	6	424	0.0e+00	594	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
649930069	586	40.25	178	580	18	402	6.0e-95	341	COG4624	Iron only hydrogenase large subunit, C-terminal domain	411
649930070	76	48.65	1	72	1	74	2.0e-16	77.2	COG0298	Hydrogenase maturation factor	82
649930071	379	42.36	6	370	2	374	7.0e-95	341	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
649930072	289	72.66	1	278	1	278	1.0e-122	432	COG1348	Nitrogenase subunit NifH, an ATPase	278
649930073	480	37.85	60	479	29	446	6.0e-89	321	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
649930074	487	29	12	472	2	437	7.0e-82	298	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
649930075	918	33.1	34	459	33	455	3.0e-88	320	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
649930078	109	24.32	1	107	1	106	2.0e-06	44.5	COG1433	Predicted Fe-Mo cluster-binding protein, NifX family	121
649930080	310	31.63	16	300	2	313	5.0e-44	171	COG1397	ADP-ribosylglycohydrolase	314
649930083	270	44.03	1	264	2	260	5.0e-63	234	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
649930084	437	47.24	105	430	1	312	1.0e-95	343	COG2025	Electron transfer flavoprotein, alpha subunit	313
649930085	657	27.18	261	657	1	385	1.0e-67	251	COG0247	Fe-S oxidoreductase	388
649930086	255	35.84	38	254	56	279	5.0e-48	184	COG1864	DNA/RNA endonuclease G, NUC1	281
649930087	510	28.57	2	507	3	493	1.0e-73	271	COG2939	Carboxypeptidase C (cathepsin A)	498
649930088	337	35.71	12	333	11	328	2.0e-65	243	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
649930091	283	38.89	4	282	2	288	6.0e-40	157	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
649930092	152	30.61	1	147	1	140	5.0e-17	80.3	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
649930093	468	36.47	63	319	58	323	2.0e-48	187	COG3344	Retron-type reverse transcriptase	328
649930096	771	35.46	480	760	67	336	2.0e-39	158	COG0642	Signal transduction histidine kinase	336
649930098	794	19.71	54	794	44	719	2.0e-47	184	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
649930100	162	26.03	6	149	27	171	2.0e-10	58.9	COG1633	Rubrerythrin	176
649930103	131	46.84	1	79	1	78	4.0e-12	63.7	COG1314	Preprotein translocase subunit SecG	86
649930104	251	57.2	1	249	1	246	2.0e-81	295	COG0149	Triosephosphate isomerase	251
649930105	399	54.61	1	396	1	393	0.0e+00	498	COG0126	3-phosphoglycerate kinase	395
649930106	331	66.47	2	330	1	330	0.0e+00	473	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
649930107	691	24.55	179	674	30	447	1.0e-35	145	COG5002	Signal transduction histidine kinase	459
649930108	257	29.34	1	224	4	245	5.0e-27	114	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
649930109	431	50.8	1	430	1	437	0.0e+00	540	COG0015	Adenylosuccinate lyase	438
649930111	996	35.13	184	991	6	743	0.0e+00	545	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
649930112	274	36.53	3	271	2	231	2.0e-51	196	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
649930113	478	57.02	9	458	1	456	0.0e+00	654	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
649930114	182	36.46	7	182	2	177	1.0e-37	149	COG0461	Orotate phosphoribosyltransferase	201
649930116	181	37.78	1	179	1	180	1.0e-43	169	COG4681	Uncharacterized conserved protein YaeQ, suppresses RfaH defect	181
649930118	244	38.4	3	243	2	249	2.0e-52	199	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
649930122	276	57.3	3	274	5	278	5.0e-96	344	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
649930123	327	43.33	89	327	1	236	1.0e-56	213	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
649930124	255	46.06	1	253	1	251	2.0e-71	262	COG1521	Pantothenate kinase type III	251
649930125	700	50.93	1	693	2	696	0.0e+00	795	COG0480	Translation elongation factor EF-G, a GTPase	697
649930128	288	26.42	3	191	1	180	1.0e-07	50.7	COG2229	Signal recognition particle receptor subunit beta, a GTPase	187
649930129	227	41.82	12	227	13	220	2.0e-41	162	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
649930130	178	46.55	5	174	1	165	2.0e-37	148	COG1592	Rubrerythrin	166
649930131	273	30.32	3	189	2	177	3.0e-14	72.6	COG1102	Cytidylate kinase	179
649930132	284	33.2	4	258	3	253	4.0e-32	132	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
649930134	218	41.71	31	217	25	211	4.0e-60	224	COG0177	Endonuclease III	211
649930135	285	38.11	3	284	1	286	2.0e-56	212	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
649930136	161	46.75	1	154	1	152	4.0e-42	163	COG4807	Uncharacterized conserved protein YehS, DUF1456 family	155
649930139	261	35.68	22	260	1	236	9.0e-44	170	COG0412	Dienelactone hydrolase	236
649930140	421	27.15	3	290	1	288	3.0e-35	143	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
649930141	987	20.48	1	982	1	891	1.0e-33	139	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
649930142	297	25.86	37	268	43	266	4.0e-07	49.1	COG5006	Threonine/homoserine efflux transporter RhtA	292
649930143	226	31.4	10	204	18	210	1.0e-13	70	COG1994	Zn-dependent protease (includes SpoIVFB)	230
649930144	327	44.27	1	309	3	314	4.0e-100	358	COG0180	Tryptophanyl-tRNA synthetase	314
649930145	282	40.34	19	254	4	240	1.0e-45	177	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
649930146	192	41.14	4	177	7	179	1.0e-39	155	COG1386	Chromosome segregation and condensation protein ScpB	184
649930147	266	42.81	1	265	2	278	3.0e-66	245	COG1355	Predicted class III extradiol dioxygenase, MEMO1 family	279
649930148	873	25	449	862	1	412	1.0e-45	178	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
649930148	873	31.9	312	423	2	117	6.0e-12	66.7	COG0517	CBS domain	117
649930150	343	26.6	21	324	13	320	3.0e-35	142	COG0618	nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs	332
649930151	378	40.89	3	377	24	403	7.0e-88	317	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
649930152	439	52.26	1	439	1	436	0.0e+00	497	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
649930153	342	52.92	1	338	1	341	2.0e-116	412	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
649930154	277	42.16	5	272	1	256	2.0e-72	265	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
649930155	450	53.63	1	427	1	414	0.0e+00	543	COG1004	UDP-glucose 6-dehydrogenase	414
649930156	311	37.14	1	306	1	310	8.0e-55	207	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649930157	138	25.27	2	92	24	114	2.0e-11	61.5	COG2919	Cell division protein FtsB	117
649930159	554	42.93	1	554	3	577	0.0e+00	544	COG0018	Arginyl-tRNA synthetase	577
649930160	273	20.83	73	264	26	212	2.0e-05	43.5	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
649930162	62	48.28	6	62	7	64	4.0e-10	56.6	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
649930163	468	40.04	1	463	7	470	0.0e+00	479	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
649930165	421	55.86	1	401	1	395	0.0e+00	554	COG0282	Acetate kinase	396
649930166	333	50.75	3	333	1	325	2.0e-96	346	COG0280	Phosphotransacetylase	327
649930167	165	47.1	2	154	9	162	1.0e-41	162	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
649930168	158	51.59	1	157	2	157	2.0e-46	178	COG0315	Molybdenum cofactor biosynthesis enzyme	157
649930169	404	44.84	5	398	9	403	2.0e-101	362	COG0303	Molybdopterin biosynthesis enzyme	404
649930171	326	43.25	3	326	2	322	5.0e-89	321	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
649930172	142	31.65	4	142	2	159	1.0e-23	101	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
649930174	455	46.77	1	455	2	460	0.0e+00	483	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649930175	1009	30.7	3	671	2	544	9.0e-90	325	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
649930176	279	28.57	2	209	1	191	6.0e-39	154	COG0437	Fe-S-cluster-containing dehydrogenase component	203
649930177	403	27.27	17	370	15	384	6.0e-31	128	COG5557	Ni/Fe-hydrogenase 2 integral membrane subunit HybB	401
649930178	466	37.05	10	245	18	264	1.0e-46	180	COG1526	Formate dehydrogenase assembly factor FdhD	266
649930180	151	34.07	1	134	1	133	1.0e-15	76.2	COG2703	Hemerythrin	144
649930181	251	59.09	3	243	7	246	2.0e-86	312	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
649930182	285	24.26	146	281	2	136	4.0e-15	75.3	COG3439	Uncharacterized conserved protein, DUF302 family	137
649930183	117	59.13	1	114	3	117	3.0e-34	136	COG3189	Uncharacterized conserved protein YeaO, DUF488 family	117
649930184	648	27.05	4	642	34	858	0.0e+00	470	COG1048	Aconitase A	861
649930185	325	49.06	9	325	24	343	1.0e-106	379	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
649930186	328	54.94	3	325	1	323	3.0e-129	454	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
649930187	540	40.5	189	540	68	403	4.0e-65	242	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
649930190	345	24.52	118	306	4	208	6.0e-11	62	COG0705	Membrane associated serine protease, rhomboid family	228
649930193	169	28.46	14	143	17	137	1.0e-05	43.1	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
649930196	136	32.59	1	134	1	133	8.0e-13	66.1	COG2703	Hemerythrin	144
649930198	458	45.73	5	453	6	457	0.0e+00	465	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649930201	897	42.58	12	894	20	915	0.0e+00	793	COG0474	Magnesium-transporting ATPase (P-type)	917
649930202	659	36.7	9	375	11	386	4.0e-64	239	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
649930203	833	48.08	52	825	34	748	0.0e+00	828	COG0058	Glucan phosphorylase	750
649930204	165	37.76	12	154	12	153	7.0e-34	136	COG0835	Chemotaxis signal transduction protein	165
649930205	67	51.56	1	64	1	64	5.0e-17	79.6	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
649930207	524	36.86	4	491	3	476	1.0e-100	360	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
649930209	173	33.55	1	152	2	156	8.0e-18	83.4	COG2062	Phosphohistidine phosphatase SixA	163
649930213	438	38.8	26	437	11	391	2.0e-94	339	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
649930216	353	37.62	1	210	1	202	3.0e-23	102	COG0310	ABC-type Co2+ transport system, permease component	204
649930217	282	30.37	29	239	3	215	6.0e-17	81.6	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
649930218	252	50.21	5	232	3	235	8.0e-66	243	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
649930219	66	56.72	1	66	1	67	5.0e-21	92.5	COG1278	Cold shock protein, CspA family	67
649930220	153	51.01	1	149	2	148	2.0e-42	164	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
649930222	378	50.77	1	377	6	393	0.0e+00	485	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
649930223	381	48.97	1	377	6	393	0.0e+00	477	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
649930224	175	31.62	2	136	11	145	3.0e-17	81.5	COG4957	Predicted transcriptional regulator	148
649930225	468	36.47	63	319	58	323	2.0e-48	187	COG3344	Retron-type reverse transcriptase	328
649930226	825	33.2	15	471	30	527	3.0e-94	340	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
649930227	416	23.32	30	400	31	386	2.0e-20	93.7	COG2814	Predicted arabinose efflux permease, MFS family	394
649930230	354	23.84	3	345	10	344	8.0e-28	118	COG0628	Predicted PurR-regulated permease PerM	355
649930232	234	47.3	5	225	1	222	2.0e-75	275	COG1136	ABC-type lipoprotein export system, ATPase component	226
649930233	844	20.47	18	386	26	406	5.0e-18	87.2	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649930234	392	40	14	378	7	354	1.0e-78	287	COG5621	Predicted secreted hydrolase	354
649930237	409	23.55	90	389	1	303	3.0e-11	63.1	COG0582	Integrase	309
649930238	93	40	44	93	17	66	1.0e-03	34.9	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
649930243	446	32.77	16	301	32	327	3.0e-44	173	COG3344	Retron-type reverse transcriptase	328
649930244	512	28.31	20	326	1	327	7.0e-35	142	COG3344	Retron-type reverse transcriptase	328
649930246	123	25.2	1	120	14	135	3.0e-13	67.3	COG4190	Predicted transcriptional regulator	144
649930249	223	24.65	7	219	5	217	1.0e-08	53.4	COG1842	Phage shock protein A	225
649930251	579	32.55	2	543	6	542	3.0e-57	216	COG2268	Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain	548
649930252	204	35.18	6	202	9	206	4.0e-24	104	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
649930253	518	30.37	1	516	5	541	6.0e-72	265	COG2985	Uncharacterized membrane protein YbjL, putative transporter	544
649930254	183	24.58	3	180	1	162	3.0e-20	91.5	COG0262	Dihydrofolate reductase	167
649930256	194	33.87	16	193	18	199	1.0e-29	123	COG0605	Superoxide dismutase	204
649930257	305	21.03	88	276	23	212	3.0e-07	49.4	COG0671	Membrane-associated phospholipid phosphatase	232
649930258	418	26.32	55	307	53	352	3.0e-28	119	COG1566	Multidrug resistance efflux pump	352
649930259	240	52.68	4	225	1	224	2.0e-78	285	COG1136	ABC-type lipoprotein export system, ATPase component	226
649930260	409	32.14	19	409	1	419	8.0e-39	154	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649930261	493	20.3	17	482	29	455	5.0e-28	119	COG1538	Outer membrane protein TolC	457
649930263	258	45.24	5	254	11	257	7.0e-77	280	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
649930264	305	33.44	4	305	1	257	4.0e-45	175	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
649930266	110	54.95	1	110	2	112	6.0e-11	59.4	COG1950	Uncharacterized membrane protein YvlD, DUF360 family	120
649930267	584	45.44	1	584	12	629	0.0e+00	603	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
649930268	193	31.94	3	190	1	189	2.0e-30	125	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
649930269	434	60.97	1	433	9	437	0.0e+00	551	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
649930270	143	44.76	1	143	1	142	8.0e-38	149	COG4747	Uncharacterized conserved protein, contains tandem ACT domains	142
649930271	378	30.79	15	374	1	357	1.0e-47	184	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
649930272	379	31.34	17	376	1	360	1.0e-50	194	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
649930273	294	37.97	4	293	3	297	2.0e-44	173	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
649930274	321	41.69	8	308	9	314	2.0e-48	186	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
649930275	250	58.4	1	249	4	250	1.0e-86	313	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
649930276	247	59.66	1	238	3	236	3.0e-93	334	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
649930277	433	54.65	4	433	11	437	0.0e+00	519	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
649930282	52	66.67	1	51	1	51	5.0e-14	69.5	COG1773	Rubredoxin	55
649930283	934	58.39	5	933	1	861	0.0e+00	1169	COG1048	Aconitase A	861
649930284	96	45.26	1	95	3	89	2.0e-17	81	COG1937	DNA-binding transcriptional regulator, FrmR family	89
649930285	831	49.67	66	826	1	710	0.0e+00	760	COG2217	Cation transport ATPase	713
649930287	386	21.96	6	384	9	406	7.0e-25	108	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649930288	222	55.2	3	221	1	221	4.0e-78	284	COG1136	ABC-type lipoprotein export system, ATPase component	226
649930289	425	21.5	33	421	45	443	2.0e-29	124	COG1538	Outer membrane protein TolC	457
649930290	473	32.01	95	404	32	355	8.0e-26	112	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649930291	1045	48.75	1	1035	1	1025	0.0e+00	1147	COG3696	Cu/Ag efflux pump CusA	1027
649930295	407	32.37	103	406	22	331	2.0e-40	160	COG0642	Signal transduction histidine kinase	336
649930296	444	53.17	1	443	3	456	0.0e+00	489	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649930300	380	49.61	1	379	1	389	1.0e-87	317	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
649930301	430	27.79	1	430	1	392	3.0e-65	242	COG0183	Acetyl-CoA acetyltransferase	392
649930302	159	35.56	26	158	2	135	3.0e-28	117	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
649930303	651	36.69	80	627	1	524	1.0e-124	440	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
649930310	724	42.75	214	722	5	498	2.0e-127	450	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649930312	239	34	1	238	2	248	1.0e-34	140	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
649930314	273	40.49	1	272	2	285	2.0e-63	236	COG2996	Predicted RNA-binding protein, contains S1 domains,  virulence factor B family	287
649930315	224	48.65	5	222	10	228	5.0e-31	127	COG0670	Integral membrane protein, interacts with FtsH	233
649930317	270	45.42	1	270	1	273	4.0e-81	294	COG0266	Formamidopyrimidine-DNA glycosylase	273
649930320	445	28.21	6	319	24	326	8.0e-31	128	COG3344	Retron-type reverse transcriptase	328
649930321	234	28.84	2	210	9	222	4.0e-25	108	COG2186	DNA-binding transcriptional regulator, FadR family	241
649930323	592	40.59	26	417	4	387	2.0e-78	286	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
649930324	390	42.16	1	390	1	392	3.0e-89	322	COG0183	Acetyl-CoA acetyltransferase	392
649930325	791	35.1	2	303	1	282	2.0e-58	221	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
649930326	603	42.18	8	598	17	607	0.0e+00	585	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
649930333	160	27.85	1	155	2	154	8.0e-11	60	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649930334	58	45.45	1	55	1	55	3.0e-09	53.3	COG1773	Rubredoxin	55
649930336	226	51.36	3	219	1	220	2.0e-75	275	COG1136	ABC-type lipoprotein export system, ATPase component	226
649930337	832	29.47	4	828	8	828	4.0e-110	392	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
649930338	221	29.72	32	218	4	215	5.0e-22	97.7	COG2755	Lysophospholipase L1 or related esterase	216
649930339	537	17.84	74	436	4	336	6.0e-31	128	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
649930340	2462	32.67	13	1095	1	1044	0.0e+00	538	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
649930341	2400	22.86	1868	2007	19	145	3.0e-11	66	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
649930342	347	27.75	5	347	3	322	1.0e-39	157	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
649930343	300	24.83	13	293	2	281	5.0e-23	101	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649930344	549	27.08	1	542	5	534	4.0e-67	249	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
649930345	330	29.74	1	328	1	310	2.0e-38	153	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649930351	206	20.96	39	203	7	170	4.0e-07	48.4	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
649930354	252	26.57	124	252	3	141	2.0e-06	46.1	COG4446	Uncharacterized conserved protein, DUF1499 family	141
649930355	334	23.6	164	316	54	221	2.0e-04	40.6	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
649930356	492	30.52	36	454	42	443	2.0e-51	197	COG3303	Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit	501
649930357	300	40.12	130	299	10	180	3.0e-36	145	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649930359	556	30.25	4	548	2	526	4.0e-77	282	COG1283	Na+/phosphate symporter	533
649930360	91	58.24	1	91	2	92	1.0e-22	97.9	COG0776	Bacterial nucleoid DNA-binding protein	94
649930362	438	37.47	6	431	7	432	3.0e-98	352	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
649930364	72	69.44	1	72	1	72	3.0e-25	106	COG0361	Translation initiation factor IF-1	75
649930365	187	41.86	1	129	3	131	8.0e-37	146	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
649930366	303	42.17	1	302	3	321	2.0e-78	286	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
649930367	328	41.82	7	321	2	317	4.0e-92	331	COG0502	Biotin synthase or related enzyme	335
649930368	239	38.64	4	222	3	217	9.0e-50	190	COG0132	Dethiobiotin synthetase	223
649930369	453	45.47	5	453	1	446	0.0e+00	523	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
649930370	458	52.53	1	256	1	256	2.0e-85	310	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
649930372	739	45.9	524	705	2	181	1.0e-44	174	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649930376	419	26.96	12	419	10	440	1.0e-52	200	COG2067	Long-chain fatty acid transport protein	440
649930379	308	32.78	1	297	1	292	4.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
649930381	190	35.15	12	176	16	173	9.0e-30	123	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
649930383	265	27.54	1	256	12	314	4.0e-42	165	COG1397	ADP-ribosylglycohydrolase	314
649930384	192	32.11	1	188	1	190	9.0e-37	146	COG3124	Acyl carrier protein phosphodiesterase	193
649930387	509	37.64	13	281	7	268	3.0e-60	226	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
649930388	201	29.33	48	194	8	157	6.0e-23	100	COG0835	Chemotaxis signal transduction protein	165
649930389	618	32.23	228	617	18	408	7.0e-40	158	COG0840	Methyl-accepting chemotaxis protein	408
649930390	749	31.89	3	611	79	711	3.0e-85	309	COG0643	Chemotaxis protein histidine kinase CheA	716
649930391	361	40.91	1	349	1	349	2.0e-76	279	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
649930394	474	39.35	8	471	4	453	2.0e-106	380	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649930395	398	29.17	4	398	2	403	2.0e-59	223	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
649930397	314	26.25	57	286	16	241	3.0e-22	99.1	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
649930401	269	29.57	4	259	15	268	1.0e-32	133	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
649930402	413	29.32	98	407	121	443	6.0e-20	92.1	COG1538	Outer membrane protein TolC	457
649930404	458	30.33	120	441	33	361	1.0e-20	94.8	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649930405	1023	47.51	1	1017	1	1021	0.0e+00	1088	COG3696	Cu/Ag efflux pump CusA	1027
649930410	220	46.53	21	218	4	204	4.0e-46	177	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
649930411	185	32.35	2	136	11	145	1.0e-16	80	COG4957	Predicted transcriptional regulator	148
649930412	327	40.37	2	322	7	317	6.0e-74	270	COG0837	Glucokinase	320
649930413	198	26.34	8	192	5	188	2.0e-18	86.2	COG3009	Uncharacterized lipoprotein YmbA	190
649930414	561	35.32	7	558	1	541	2.0e-115	410	COG3008	Paraquat-inducible protein B	553
649930418	733	24.23	354	730	12	360	3.0e-34	140	COG3852	Signal transduction histidine kinase, nitrogen specific	363
649930419	359	42.61	1	349	1	349	1.0e-81	296	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
649930420	762	30.16	53	629	107	716	6.0e-90	325	COG0643	Chemotaxis protein histidine kinase CheA	716
649930421	1050	31.37	744	1049	105	407	2.0e-42	168	COG0840	Methyl-accepting chemotaxis protein	408
649930422	321	30.2	168	312	6	154	9.0e-21	94.6	COG0835	Chemotaxis signal transduction protein	165
649930423	484	33.09	7	280	1	265	5.0e-56	212	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
649930425	112	23.08	11	112	1	103	5.0e-08	49.7	COG0789	DNA-binding transcriptional regulator, MerR family	124
649930426	92	44.57	1	92	2	93	2.0e-23	100	COG0776	Bacterial nucleoid DNA-binding protein	94
649930427	801	41.42	142	801	1	650	0.0e+00	562	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
649930428	352	56.47	19	351	6	335	2.0e-125	442	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
649930429	117	69.57	1	115	1	115	5.0e-36	142	COG0292	Ribosomal protein L20	118
649930430	65	56.92	1	65	1	65	4.0e-11	59.5	COG0291	Ribosomal protein L35	65
649930431	177	63.03	13	177	12	176	3.0e-60	224	COG0290	Translation initiation factor IF-3	176
649930432	636	56.81	36	636	1	584	0.0e+00	762	COG0441	Threonyl-tRNA synthetase	589
649930434	357	31.07	32	353	1	329	1.0e-41	163	COG0859	ADP-heptose:LPS heptosyltransferase	334
649930435	511	43.75	3	508	2	456	0.0e+00	467	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649930436	555	27.76	297	554	86	334	5.0e-37	149	COG0642	Signal transduction histidine kinase	336
649930437	382	45.62	6	382	5	377	2.0e-111	395	COG1454	Alcohol dehydrogenase, class IV	377
649930438	195	31.51	41	184	46	181	2.0e-13	68.7	COG1525	Endonuclease YncB, thermonuclease family	192
649930439	417	26.54	26	412	23	387	5.0e-34	139	COG5557	Ni/Fe-hydrogenase 2 integral membrane subunit HybB	401
649930440	317	58.9	4	311	1	300	2.0e-108	385	COG0031	Cysteine synthase	300
649930441	417	45.35	10	417	8	426	0.0e+00	503	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
649930442	70	34.78	1	69	3	68	2.0e-07	47.1	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
649930443	270	51.57	1	249	1	254	7.0e-76	277	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
649930444	133	36.19	1	105	1	104	8.0e-15	72.9	COG1310	Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif	134
649930445	316	36.55	14	300	20	304	2.0e-53	202	COG2221	Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits	317
649930446	74	32.88	1	72	5	77	2.0e-10	57.2	COG0425	TusA-related sulfurtransferase	78
649930447	356	47.77	3	355	2	352	9.0e-119	420	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
649930448	352	36.41	2	350	1	352	2.0e-72	266	COG4148	ABC-type molybdate transport system, ATPase component	352
649930449	227	49.55	4	226	1	223	3.0e-52	198	COG4149	ABC-type molybdate transport system, permease component	225
649930450	549	31.58	168	547	32	408	1.0e-49	191	COG0840	Methyl-accepting chemotaxis protein	408
649930454	470	47.22	255	469	20	225	5.0e-67	248	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
649930457	373	24.22	1	366	1	381	2.0e-23	103	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649930458	367	20.41	1	367	1	380	2.0e-16	80.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649930461	333	19.02	148	323	1	205	2.0e-10	60	COG0778	Nitroreductase	207
649930462	433	21.5	1	428	3	419	1.0e-17	84.8	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
649930463	760	25.54	8	500	7	458	7.0e-51	196	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
649930464	351	33.8	50	264	31	239	1.0e-29	124	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
649930466	259	28.92	5	251	1	226	8.0e-33	134	COG4464	Tyrosine-protein phosphatase YwqE	254
649930468	281	33.45	3	275	1	251	1.0e-40	160	COG0543	NAD(P)H-flavin reductase	252
649930469	252	36.49	1	213	1	216	1.0e-37	150	COG1941	Coenzyme F420-reducing hydrogenase, gamma subunit	247
649930470	423	31.55	1	423	1	428	8.0e-74	271	COG3259	Coenzyme F420-reducing hydrogenase, alpha subunit	441
649930472	280	23.62	3	279	2	302	1.0e-19	90.8	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649930474	476	46.28	4	360	13	369	1.0e-99	356	COG1488	Nicotinic acid phosphoribosyltransferase	405
649930475	210	28.21	4	189	5	194	4.0e-30	124	COG1335	Nicotinamidase-related amidase	205
649930476	355	60.63	1	348	2	348	0.0e+00	537	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
649930477	532	45.4	1	325	4	324	5.0e-87	315	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
649930478	208	49.04	1	202	1	207	6.0e-61	227	COG0135	Phosphoribosylanthranilate isomerase	208
649930479	451	63.11	3	431	2	432	0.0e+00	647	COG1350	Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB)	432
649930480	266	51.74	8	266	1	254	6.0e-80	290	COG0134	Indole-3-glycerol phosphate synthase	254
649930481	352	52	1	350	3	338	4.0e-114	404	COG0547	Anthranilate phosphoribosyltransferase	338
649930482	189	65.96	1	187	3	190	1.0e-84	305	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
649930486	274	21.4	1	271	2	299	2.0e-14	73.1	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
649930487	491	48.85	20	491	1	462	0.0e+00	514	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
649930488	644	51.72	1	639	2	618	0.0e+00	718	COG0326	Molecular chaperone, HSP90 family	623
649930490	1006	25.13	507	873	12	361	4.0e-29	124	COG3852	Signal transduction histidine kinase, nitrogen specific	363
649930492	215	31.71	14	214	7	211	3.0e-32	131	COG3762	Uncharacterized membrane protein	213
649930493	288	36.9	1	288	6	271	1.0e-44	173	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
649930494	194	47.4	1	192	1	185	2.0e-54	205	COG1704	Uncharacterized conserved protein	185
649930496	280	29.84	3	280	13	315	1.0e-36	147	COG0226	ABC-type phosphate transport system, periplasmic component	318
649930498	280	21.3	71	262	18	233	2.0e-10	60	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
649930500	467	30.62	1	353	7	368	9.0e-42	165	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649930502	299	37.46	1	299	2	300	3.0e-64	238	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
649930503	572	44.58	54	537	10	478	7.0e-111	394	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
649930505	300	39.18	3	292	4	291	6.0e-67	247	COG0341	Preprotein translocase subunit SecF	305
649930506	532	44.74	1	532	2	506	1.0e-123	436	COG0342	Preprotein translocase subunit SecD	506
649930507	107	48.91	15	106	1	90	2.0e-23	100	COG1862	Preprotein translocase subunit YajC	97
649930508	371	62.09	6	368	1	362	0.0e+00	527	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
649930509	341	57.56	1	340	1	342	0.0e+00	460	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
649930512	320	55.56	4	316	1	312	9.0e-119	419	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
649930513	328	50.8	1	311	1	266	4.0e-100	357	COG4608	ABC-type oligopeptide transport system, ATPase component	309
649930514	94	36.78	5	90	8	94	2.0e-08	50.6	COG0640	DNA-binding transcriptional regulator, ArsR family	110
649930515	446	34.87	5	446	3	454	4.0e-80	292	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
649930516	149	39.07	1	149	2	152	6.0e-35	140	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
649930517	553	47.13	1	553	1	557	0.0e+00	506	COG0497	DNA repair ATPase RecN	557
649930518	288	41.11	2	287	1	281	7.0e-66	244	COG0061	NAD kinase	281
649930519	831	49.56	21	818	12	750	0.0e+00	865	COG0058	Glucan phosphorylase	750
649930520	434	55.76	1	433	1	433	0.0e+00	596	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
649930521	319	47.15	1	304	2	317	2.0e-84	305	COG0205	6-phosphofructokinase	347
649930522	126	35.04	6	119	5	121	6.0e-20	89.6	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
649930524	206	30.66	3	205	2	207	2.0e-24	105	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
649930526	163	56.25	1	141	2	145	3.0e-46	177	COG0328	Ribonuclease HI	154
649930527	217	28.02	9	211	35	234	5.0e-23	101	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
649930529	337	43.4	37	300	1	260	3.0e-69	255	COG1180	Pyruvate-formate lyase-activating enzyme	260
649930531	384	22.15	53	370	76	381	4.0e-16	79.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649930532	366	45.7	1	366	5	375	1.0e-81	296	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
649930533	634	36.59	16	610	15	599	0.0e+00	463	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
649930535	283	34.43	9	279	1	270	1.0e-40	160	COG1792	Cell shape-determining protein MreC	284
649930536	162	25.55	6	138	2	136	5.0e-18	83.8	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
649930537	301	54.33	7	292	2	286	7.0e-101	360	COG1209	dTDP-glucose pyrophosphorylase	286
649930539	231	57.76	1	231	1	230	2.0e-80	291	COG1489	DNA-binding protein, stimulates sugar fermentation	235
649930541	147	27.36	43	147	40	144	1.0e-13	69.6	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
649930543	283	47.35	34	274	20	263	4.0e-64	238	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
649930544	341	48.52	6	338	16	346	8.0e-105	373	COG2957	Agmatine/peptidylarginine deiminase	346
649930545	293	36.64	2	290	1	273	2.0e-50	193	COG0388	Predicted amidohydrolase	274
649930546	1385	32.7	683	1384	83	866	2.0e-96	348	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
649930548	97	42.86	1	97	1	98	2.0e-27	113	COG4680	mRNA-degrading endonuclease (mRNA interferase) HigB, toxic component of the HigAB toxin-antitoxin module	98
649930549	125	51.28	2	116	4	120	3.0e-32	130	COG5499	Antitoxin component HigA of the HigAB toxin-antitoxin module, contains an N-terminal HTH domain	120
649930552	197	46.49	10	194	9	185	7.0e-49	186	COG1704	Uncharacterized conserved protein	185
649930553	661	28.05	24	322	13	294	3.0e-22	100	COG0501	Zn-dependent protease with chaperone function	302
649930556	412	21.12	12	404	25	429	7.0e-20	91.8	COG2271	Sugar phosphate permease	448
649930557	289	25.3	31	276	32	274	1.0e-09	57.2	COG5006	Threonine/homoserine efflux transporter RhtA	292
649930558	153	38.03	1	142	2	138	6.0e-34	136	COG1959	DNA-binding transcriptional regulator, IscR family	150
649930559	494	27.79	45	492	10	461	5.0e-35	142	COG0471	Di- and tricarboxylate transporter	461
649930561	145	22.86	3	141	1	138	3.0e-07	47.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
649930564	144	36.84	5	137	1	128	1.0e-25	108	COG5496	Predicted thioesterase	130
649930566	200	28.37	1	180	6	212	7.0e-14	70.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649930570	1364	34.46	492	811	14	329	3.0e-43	171	COG0642	Signal transduction histidine kinase	336
649930571	279	35.56	7	274	6	266	5.0e-52	197	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
649930573	786	29.23	16	785	18	755	3.0e-119	423	COG1882	Pyruvate-formate lyase	755
649930574	294	32.74	3	282	19	248	6.0e-47	181	COG1180	Pyruvate-formate lyase-activating enzyme	260
649930575	67	37.31	1	67	6	72	6.0e-07	45.7	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
649930577	253	31.89	3	251	1	254	5.0e-22	98.2	COG0730	Uncharacterized membrane protein YfcA	258
649930579	194	45.9	3	184	4	178	2.0e-48	185	COG0241	Histidinol phosphatase or a related phosphatase	181
649930580	189	57.39	1	176	1	176	4.0e-60	223	COG0279	Phosphoheptose isomerase	176
649930581	337	25.79	6	190	5	219	2.0e-16	80.2	COG1216	Glycosyltransferase, GT2 family	305
649930582	347	69.88	8	346	1	341	3.0e-128	451	COG1077	Actin-like ATPase involved in cell morphogenesis	342
649930584	296	33.57	13	293	4	247	3.0e-60	225	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
649930585	118	28.57	15	115	11	115	3.0e-04	37.2	COG4980	Gas vesicle protein	115
649930586	367	21.08	2	367	1	302	1.0e-20	94.6	COG0492	Thioredoxin reductase	305
649930587	263	24.86	16	196	44	223	2.0e-11	63.1	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
649930588	780	38.11	10	780	1	748	0.0e+00	603	COG3605	Signal transduction protein containing GAF and PtsI domains	756
649930591	171	50.6	1	166	1	166	8.0e-55	206	COG1528	Ferritin	167
649930592	268	22.48	1	256	2	254	2.0e-10	60.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649930594	254	45.19	6	206	3	210	5.0e-36	144	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
649930595	461	48.79	9	459	6	456	0.0e+00	518	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649930596	206	36.63	1	191	1	199	4.0e-36	144	COG0655	Multimeric flavodoxin WrbA	207
649930599	375	30.04	93	341	9	248	2.0e-39	156	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
649930600	400	35.74	68	381	4	315	2.0e-74	273	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649930601	367	30.53	231	359	2	131	2.0e-21	97.2	COG1917	Cupin domain protein related to quercetin dioxygenase	131
649930602	96	44.3	7	85	16	91	9.0e-12	61.6	COG5304	Predicted DNA binding protein, CopG/RHH family	92
649930603	446	32.77	16	301	32	327	3.0e-44	173	COG3344	Retron-type reverse transcriptase	328
649930605	255	31.67	20	254	5	202	2.0e-33	135	COG0437	Fe-S-cluster-containing dehydrogenase component	203
649930607	104	34.04	1	93	8	101	5.0e-07	46	COG0640	DNA-binding transcriptional regulator, ArsR family	110
649930611	127	33.65	12	112	7	109	3.0e-09	54.1	COG0526	Thiol-disulfide isomerase or thioredoxin	127
649930612	228	29.72	16	224	10	220	1.0e-18	86.9	COG0785	Cytochrome c biogenesis protein CcdA	220
649930615	793	24.58	110	790	15	626	6.0e-54	206	COG0296	1,4-alpha-glucan branching enzyme	628
649930618	232	43.3	5	226	3	225	2.0e-58	219	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649930619	456	38.54	152	448	31	329	4.0e-44	173	COG0642	Signal transduction histidine kinase	336
649930628	418	46.06	1	401	1	400	1.0e-107	383	COG1252	NADH dehydrogenase, FAD-containing subunit	405
649930629	144	34.15	23	143	17	139	4.0e-19	87.4	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
649930630	378	41.87	1	373	5	370	4.0e-105	374	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649930632	308	24.41	1	295	2	291	3.0e-17	82.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649930633	546	21.54	21	453	8	422	5.0e-30	126	COG3463	Uncharacterized membrane protein	458
649930637	337	19.5	103	336	6	241	1.0e-07	51.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649930639	113	32.76	4	113	6	120	2.0e-13	68	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
649930640	201	24.39	46	192	49	212	4.0e-07	48.4	COG3047	Outer membrane protein W	213
649930642	303	27.92	64	302	81	319	1.0e-17	84.5	COG2064	Pilus assembly protein TadC	320
649930643	321	27.95	1	321	1	309	2.0e-44	173	COG4965	Flp pilus assembly protein TadB	309
649930644	434	55.28	39	398	1	355	9.0e-114	403	COG4962	Pilus assembly protein, ATPase of CpaF family	355
649930647	493	37.15	126	476	76	416	8.0e-59	221	COG4964	Flp pilus assembly protein, secretin CpaC	455
649930648	308	32.1	7	262	5	270	2.0e-30	126	COG3745	Flp pilus assembly protein CpaB	276
649930650	65	36.96	19	64	9	54	1.0e-03	34.4	COG3847	Flp pilus assembly protein, pilin Flp	58
649930651	64	33.93	7	62	1	56	1.0e-04	37.9	COG3847	Flp pilus assembly protein, pilin Flp	58
649930656	625	27.82	1	625	2	651	1.0e-68	254	COG1269	Archaeal/vacuolar-type H+-ATPase subunit I/STV1	660
649930658	192	25.81	1	179	2	187	5.0e-07	47.6	COG1390	Archaeal/vacuolar-type H+-ATPase subunit E/Vma4	194
649930659	320	18.96	44	290	52	313	3.0e-03	36.1	COG1527	Archaeal/vacuolar-type H+-ATPase subunit C/Vma6	346
649930660	106	27.72	1	99	2	99	3.0e-08	50.2	COG1436	Archaeal/vacuolar-type H+-ATPase subunit F/Vma7	104
649930661	543	47.62	1	535	1	546	0.0e+00	661	COG1155	Archaeal/vacuolar-type H+-ATPase catalytic subunit A/Vma1	588
649930662	440	55.3	7	435	6	439	0.0e+00	537	COG1156	Archaeal/vacuolar-type H+-ATPase subunit B/Vma2	463
649930663	213	30.92	2	208	5	208	2.0e-23	102	COG1394	Archaeal/vacuolar-type H+-ATPase subunit D/Vma8	211
649930666	1201	51.36	14	1201	30	1223	0.0e+00	1541	COG5013	Nitrate reductase alpha subunit	1227
649930667	484	54.08	1	461	1	466	0.0e+00	649	COG1140	Nitrate reductase beta subunit	513
649930668	181	27.98	1	166	1	159	5.0e-18	84.2	COG2180	Nitrate reductase assembly protein NarJ, required for insertion of molybdenum cofactor	179
649930669	221	34.82	1	219	1	224	2.0e-26	113	COG2181	Nitrate reductase gamma subunit	228
649930670	461	40.09	14	455	1	404	2.0e-91	330	COG2223	Nitrate/nitrite transporter NarK	417
649930671	254	45.72	1	254	4	268	1.0e-61	230	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
649930677	267	17.94	6	267	4	252	3.0e-05	42.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649930682	381	25.14	27	378	3	331	6.0e-31	128	COG0859	ADP-heptose:LPS heptosyltransferase	334
649930685	311	23.89	12	223	4	219	1.0e-22	100	COG1216	Glycosyltransferase, GT2 family	305
649930686	679	27.88	2	208	1	221	1.0e-19	91.7	COG1216	Glycosyltransferase, GT2 family	305
649930687	379	25.92	9	377	4	377	2.0e-30	127	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649930690	435	46.92	3	262	2	243	4.0e-82	299	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
649930691	279	35.85	15	279	2	263	5.0e-43	168	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
649930692	250	25.41	4	243	1	240	2.0e-20	92.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649930693	256	23.9	1	250	3	241	7.0e-17	81.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649930694	325	31.63	1	312	2	281	5.0e-39	155	COG1216	Glycosyltransferase, GT2 family	305
649930695	280	25.99	5	275	13	286	2.0e-18	86.9	COG0382	4-hydroxybenzoate polyprenyltransferase	289
649930697	287	36.95	1	286	2	292	2.0e-71	262	COG1131	ABC-type multidrug transport system, ATPase component	293
649930702	457	50.54	1	457	3	459	0.0e+00	502	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649930703	541	27.65	203	541	6	354	1.0e-36	148	COG3852	Signal transduction histidine kinase, nitrogen specific	363
649930704	407	41.87	1	406	1	397	6.0e-104	371	COG1459	Type II secretory pathway, component PulF	397
649930705	366	55.52	1	353	2	353	0.0e+00	482	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
649930706	568	50.5	63	564	3	498	0.0e+00	561	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649930707	290	49.12	3	284	2	281	5.0e-74	271	COG0169	Shikimate 5-dehydrogenase	283
649930709	342	22.61	10	321	20	309	1.0e-07	50.8	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
649930710	331	42.81	1	306	1	304	2.0e-81	296	COG0196	FAD synthase	304
649930711	282	33.69	4	282	5	255	8.0e-43	167	COG0805	Sec-independent protein secretion pathway component TatC	255
649930712	737	43.48	5	705	7	705	0.0e+00	623	COG0557	Exoribonuclease R	706
649930713	706	27.36	389	677	1	287	3.0e-20	94.1	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
649930715	356	37.5	68	337	45	299	2.0e-59	223	COG1162	Putative ribosome biogenesis GTPase RsgA	301
649930716	144	37.29	28	144	9	126	6.0e-14	70	COG1846	DNA-binding transcriptional regulator, MarR family	126
649930717	421	25.86	24	421	43	445	2.0e-35	143	COG1538	Outer membrane protein TolC	457
649930718	359	39.64	18	353	10	346	1.0e-71	263	COG1566	Multidrug resistance efflux pump	352
649930722	239	58.92	2	239	1	241	9.0e-83	299	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
649930723	454	47.69	1	442	6	455	2.0e-121	429	COG1109	Phosphomannomutase	464
649930725	252	38.17	1	235	4	244	5.0e-42	164	COG1624	Diadenylate cyclase (c-di-AMP synthetase), DisA_N domain	247
649930726	278	52.65	17	278	6	265	4.0e-73	268	COG0294	Dihydropteroate synthase	274
649930727	612	60.33	9	607	1	596	0.0e+00	762	COG0465	ATP-dependent Zn proteases	596
649930728	458	36.18	1	241	7	247	8.0e-38	151	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
649930730	284	52.1	1	284	3	288	5.0e-81	294	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
649930731	326	48	1	325	1	317	4.0e-91	328	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
649930732	532	32.61	1	531	6	554	9.0e-94	338	COG0747	ABC-type transport system, periplasmic component	556
649930734	520	43.07	3	332	2	333	1.0e-87	317	COG2187	Aminoglycoside phosphotransferase family enzyme	337
649930736	1087	22.42	1	483	2	464	6.0e-50	193	COG0591	Na+/proline symporter	493
649930737	113	30.09	1	112	3	115	3.0e-13	67	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
649930738	141	32.8	9	128	7	127	4.0e-12	64.2	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
649930739	257	45.79	1	256	6	276	1.0e-61	230	COG0682	Prolipoprotein diacylglyceryltransferase	287
649930741	114	33.91	2	114	1	112	3.0e-25	107	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
649930742	256	58.37	2	244	1	245	1.0e-84	306	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
649930743	613	35.27	1	475	1	458	4.0e-105	376	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
649930744	832	28.02	390	831	20	450	2.0e-40	161	COG5002	Signal transduction histidine kinase	459
649930745	458	48.69	1	458	4	456	0.0e+00	502	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649930746	336	41.99	1	330	2	329	1.0e-88	319	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
649930747	224	30.98	1	184	8	161	1.0e-19	90.4	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
649930748	459	47.23	80	458	1	379	5.0e-99	355	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
649930749	385	31.69	15	380	22	386	4.0e-33	135	COG3004	Na+/H+ antiporter NhaA	390
649930750	188	40.14	42	188	37	182	1.0e-34	139	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
649930755	699	37.87	482	643	5	173	4.0e-30	127	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649930756	112	53.54	12	110	2	100	2.0e-27	113	COG3657	Putative component of the toxin-antitoxin plasmid stabilization module	100
649930757	100	46.07	10	98	12	99	8.0e-17	78.4	COG3636	DNA-binding prophage protein	100
649930760	173	52.76	3	165	5	167	1.0e-43	168	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
649930761	330	40.92	4	322	13	337	7.0e-70	257	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
649930762	215	51.69	7	213	3	209	2.0e-64	238	COG2518	Protein-L-isoaspartate O-methyltransferase	209
649930763	248	53.6	1	245	1	250	1.0e-85	309	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
649930764	245	42.92	5	235	3	235	4.0e-61	228	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
649930765	212	34.04	8	191	21	208	1.0e-23	103	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
649930767	314	46.98	2	310	6	320	3.0e-87	315	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
649930768	134	51.54	1	130	8	137	6.0e-38	149	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
649930769	176	48.85	2	175	25	197	2.0e-49	188	COG2109	ATP:corrinoid adenosyltransferase	198
649930772	269	30.18	48	262	7	228	2.0e-10	60	COG2202	PAS domain	232
649930773	213	18.98	1	213	1	199	3.0e-12	65.4	COG3637	Opacity protein and related surface antigens	199
649930777	135	30.77	2	130	1	130	1.0e-14	72.3	COG2703	Hemerythrin	144
649930778	399	43.72	13	392	9	386	5.0e-94	338	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
649930780	540	41.04	1	536	3	526	0.0e+00	531	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
649930783	231	52.61	3	230	2	228	6.0e-77	280	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
649930784	193	51.85	5	192	4	191	3.0e-56	211	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
649930786	436	62.07	1	431	2	435	0.0e+00	650	COG1206	Folate-dependent tRNA-U54 methylase TrmFO/GidA	439
649930787	779	38.81	647	779	5	138	1.0e-26	115	COG0551	ssDNA-binding Zn-finger and Zn-ribbon domains of topoisomerase 1	140
649930787	779	47.48	4	611	2	570	0.0e+00	630	COG0550	DNA topoisomerase IA	570
649930788	359	43.54	5	359	8	350	8.0e-90	324	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
649930790	412	50.43	12	356	6	345	9.0e-102	364	COG0826	Collagenase-like protease, PrtC family	347
649930794	1890	33.93	1553	1720	27	186	2.0e-24	109	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
649930797	460	41.43	6	459	4	454	3.0e-104	372	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
649930799	450	54.05	3	446	2	443	0.0e+00	604	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
649930801	490	49.02	35	490	33	483	0.0e+00	510	COG0260	Leucyl aminopeptidase	485
649930802	246	37.89	4	246	9	258	1.0e-45	176	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
649930803	509	22.25	22	387	65	387	3.0e-21	96.9	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
649930805	424	31.69	1	419	8	433	2.0e-75	276	COG0612	Predicted Zn-dependent peptidase	438
649930807	295	27.63	17	241	58	261	2.0e-11	63.8	COG2324	Uncharacterized membrane protein	281
649930808	356	19.87	9	305	10	294	1.0e-20	94	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
649930809	258	37.21	1	258	8	263	2.0e-49	189	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
649930811	175	37.65	1	165	1	165	2.0e-33	135	COG0066	3-isopropylmalate dehydratase small subunit	191
649930812	427	47.69	1	427	1	423	0.0e+00	523	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
649930813	342	33.5	59	256	1	196	5.0e-39	155	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
649930814	67	56.72	1	66	1	67	9.0e-21	91.7	COG1278	Cold shock protein, CspA family	67
649930817	515	53.24	7	418	1	409	2.0e-122	433	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
649930818	250	39.15	1	233	4	234	2.0e-40	159	COG1183	Phosphatidylserine synthase	234
649930819	219	39.19	1	215	21	234	6.0e-43	167	COG0688	Phosphatidylserine decarboxylase	239
649930820	163	58.49	1	159	3	161	6.0e-49	186	COG0440	Acetolactate synthase, small subunit	163
649930821	566	52.22	2	562	1	549	0.0e+00	672	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
649930822	553	53.2	1	550	11	570	0.0e+00	698	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
649930823	230	37.55	1	224	1	220	2.0e-33	135	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
649930824	367	41.02	13	364	3	375	4.0e-53	202	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
649930825	385	60.47	1	381	1	380	0.0e+00	529	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
649930826	249	35.98	13	249	27	263	2.0e-25	109	COG0575	CDP-diglyceride synthetase	265
649930827	248	55.79	7	239	13	245	5.0e-86	310	COG0020	Undecaprenyl pyrophosphate synthase	245
649930828	185	57.84	1	185	3	187	2.0e-58	218	COG0233	Ribosome recycling factor	187
649930829	240	66.81	2	238	1	238	6.0e-92	330	COG0528	Uridylate kinase	238
649930831	255	60	1	250	1	249	5.0e-101	360	COG0052	Ribosomal protein S2	252
649930832	296	34.92	1	292	1	290	4.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
649930833	490	39.88	20	362	1	338	2.0e-110	393	COG0059	Ketol-acid reductoisomerase	338
649930837	146	50.34	1	146	1	147	3.0e-32	131	COG0359	Ribosomal protein L9	148
649930838	313	23.81	19	305	18	306	1.0e-09	58	COG4241	Uncharacterized conserved protein YybS, DUF2232 family	314
649930839	93	58.57	15	84	6	75	8.0e-20	88.7	COG0238	Ribosomal protein S18	75
649930840	133	38.53	3	111	1	109	1.0e-22	98.8	COG0360	Ribosomal protein S6	112
649930841	364	62.1	1	364	1	372	0.0e+00	512	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
649930842	188	52.94	4	188	3	189	2.0e-66	244	COG0193	Peptidyl-tRNA hydrolase	190
649930843	195	40.66	5	95	3	90	2.0e-15	76.1	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
649930844	316	63.61	1	315	1	313	5.0e-124	437	COG0462	Phosphoribosylpyrophosphate synthetase	314
649930849	133	31.01	2	126	1	129	3.0e-15	74.2	COG2703	Hemerythrin	144
649930850	221	47.59	45	206	40	205	4.0e-43	167	COG2930	Lipid-binding SYLF domain	227
649930852	303	29.21	5	302	10	321	1.0e-27	116	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
649930853	652	23.03	2	652	3	699	5.0e-51	195	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
649930856	409	21.97	31	360	18	355	1.0e-32	134	COG0641	Sulfatase maturation enzyme AslB, radical SAM superfamily	378
649930863	280	43.16	1	280	1	284	3.0e-79	288	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
649930864	398	36.93	10	398	19	399	5.0e-78	284	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
649930866	207	33.17	9	207	24	225	5.0e-39	154	COG0220	tRNA G46 methylase TrmB	227
649930867	544	34.31	132	542	1	408	2.0e-47	184	COG0840	Methyl-accepting chemotaxis protein	408
649930868	477	38.57	1	472	29	487	2.0e-106	379	COG0513	Superfamily II DNA and RNA helicase	513
649930869	333	26.69	9	330	2	309	3.0e-28	119	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
649930870	386	37.43	7	371	1	360	2.0e-75	276	COG1565	SAM-dependent methyltransferase, MidA family	370
649930871	210	29.17	11	191	4	193	1.0e-15	76.9	COG1011	FMN phosphatase YigB, HAD superfamily	229
649930872	466	54.18	1	465	2	468	0.0e+00	614	COG1027	Aspartate ammonia-lyase	471
649930873	73	60	5	73	15	84	8.0e-18	81.9	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
649930874	395	33.42	33	395	59	438	1.0e-61	230	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
649930875	781	32.95	4	780	1	753	2.0e-122	433	COG1193	dsDNA-specific endonuclease/ATPase MutS2	753
649930876	306	41.61	2	128	1	137	4.0e-30	125	COG0262	Dihydrofolate reductase	167
649930877	212	35.98	4	189	6	194	5.0e-31	127	COG1381	Recombinational DNA repair protein (RecF pathway)	251
649930878	449	57.31	8	444	1	434	0.0e+00	539	COG0305	Replicative DNA helicase	435
649930881	188	22.34	10	165	1	197	9.0e-12	63.3	COG1335	Nicotinamidase-related amidase	205
649930882	478	50.32	1	475	2	458	0.0e+00	529	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649930883	361	33.52	12	361	12	356	1.0e-67	250	COG3852	Signal transduction histidine kinase, nitrogen specific	363
649930884	321	48.9	7	321	4	320	2.0e-89	322	COG0042	tRNA-dihydrouridine synthase	323
649930885	279	25.3	8	255	1	223	6.0e-29	121	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
649930886	160	36.24	9	156	2	150	2.0e-30	124	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
649930887	136	29.77	7	136	4	128	4.0e-12	64.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
649930888	170	31.58	31	120	12	104	7.0e-05	40.4	COG0727	Fe-S-cluster containining protein	132
649930891	256	61.33	1	256	1	255	1.0e-99	356	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
649930892	564	46.67	185	544	3	354	1.0e-99	357	COG2262	50S ribosomal subunit-associated GTPase HflX	411
649930893	205	43.15	6	201	5	201	2.0e-43	168	COG2860	Uncharacterized membrane protein YeiH	209
649930894	155	55.92	1	152	1	152	1.0e-48	185	COG4119	Predicted NTP pyrophosphohydrolase, NUDIX family	161
649930895	731	34.38	390	668	89	408	4.0e-34	140	COG0840	Methyl-accepting chemotaxis protein	408
649930896	348	46.51	1	343	2	341	2.0e-88	319	COG0430	RNA 3'-terminal phosphate cyclase	341
649930897	390	31.81	4	371	1	326	7.0e-54	205	COG0205	6-phosphofructokinase	347
649930901	385	44.73	1	382	1	388	3.0e-86	312	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
649930902	281	48.94	1	281	2	283	4.0e-88	317	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
649930903	391	44.33	1	391	1	392	2.0e-78	286	COG0183	Acetyl-CoA acetyltransferase	392
649930905	160	27.59	51	160	27	140	3.0e-07	48.1	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
649930907	1095	37.5	753	1031	89	408	6.0e-47	183	COG0840	Methyl-accepting chemotaxis protein	408
649930911	148	43.48	16	130	1	114	8.0e-24	102	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
649930912	692	38.07	33	688	22	711	0.0e+00	492	COG2217	Cation transport ATPase	713
649930916	131	26	23	71	14	63	2.0e-03	34.6	COG2608	Copper chaperone CopZ	71
649930922	767	59.7	434	763	2	329	2.0e-126	447	COG0620	Methionine synthase II (cobalamin-independent)	330
649930924	66	55.22	1	66	1	67	4.0e-21	92.9	COG1278	Cold shock protein, CspA family	67
649930926	304	30.18	18	299	26	298	2.0e-47	183	COG1560	Lauroyl/myristoyl acyltransferase	308
649930927	157	48.67	1	146	5	154	1.0e-28	119	COG1522	DNA-binding transcriptional regulator, Lrp family	154
649930928	422	35.25	14	388	17	394	2.0e-83	303	COG0019	Diaminopimelate decarboxylase	394
649930933	392	38.22	45	392	64	408	3.0e-47	183	COG0840	Methyl-accepting chemotaxis protein	408
649930934	1527	59.8	709	1200	1	483	0.0e+00	680	COG0069	Glutamate synthase domain 2	485
649930935	493	42.92	22	487	1	451	0.0e+00	481	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
649930939	313	24.9	43	287	40	271	3.0e-09	56.4	COG5006	Threonine/homoserine efflux transporter RhtA	292
649930941	205	31.19	5	205	1	177	3.0e-26	111	COG1183	Phosphatidylserine synthase	234
649930942	604	33.28	20	602	26	626	5.0e-95	342	COG0296	1,4-alpha-glucan branching enzyme	628
649930943	1153	18.11	1	511	5	519	3.0e-07	51.6	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
649930947	462	36.15	89	462	57	438	6.0e-67	248	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
649930949	452	23.02	44	397	61	447	3.0e-29	123	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649930950	371	26.84	137	365	48	278	1.0e-11	64.5	COG0842	ABC-type multidrug transport system, permease component	286
649930951	314	41.91	8	304	4	293	5.0e-69	254	COG1131	ABC-type multidrug transport system, ATPase component	293
649930953	240	26.44	14	186	7	173	2.0e-08	53.1	COG2091	Phosphopantetheinyl transferase	223
649930954	2678	28.62	729	1783	4	1034	9.0e-114	406	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
649930959	401	45.04	26	394	16	388	8.0e-117	413	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
649930960	328	29.71	4	326	2	312	4.0e-38	152	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649930962	180	41.51	14	172	6	158	4.0e-40	157	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
649930963	616	54.95	126	549	1	424	0.0e+00	601	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
649930964	926	40.93	4	906	3	939	0.0e+00	962	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
649930965	217	39.38	16	205	6	192	2.0e-34	139	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
649930966	316	22.7	1	139	1	136	1.0e-10	61	COG1943	REP element-mobilizing transposase RayT	136
649930968	340	24.39	103	327	52	291	4.0e-20	92.6	COG4974	Site-specific recombinase XerD	300
649930969	293	40.21	4	277	12	294	9.0e-59	220	COG4227	Antirestriction protein ArdC	316
649930972	261	35.8	10	249	9	251	6.0e-41	161	COG1484	DNA replication protein DnaC	254
649930978	249	43.03	2	244	19	258	7.0e-63	234	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
649930979	240	45.22	8	237	12	234	2.0e-55	209	COG0284	Orotidine-5'-phosphate decarboxylase	240
649930980	573	47.01	1	565	1	500	0.0e+00	580	COG0442	Prolyl-tRNA synthetase	500
649930981	353	57.88	5	352	6	354	0.0e+00	492	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
649930982	217	15.53	7	203	1	205	6.0e-19	87.6	COG1335	Nicotinamidase-related amidase	205
649930983	603	43.04	4	537	5	535	0.0e+00	487	COG1574	Predicted amidohydrolase YtcJ	535
649930984	177	50	27	176	18	173	5.0e-46	177	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
649930985	566	38.27	119	556	3	431	7.0e-100	358	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
649930986	401	27.4	1	330	3	351	2.0e-34	140	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
649930989	182	34.72	4	178	3	193	3.0e-23	101	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
649930990	270	40.96	5	269	4	273	5.0e-74	271	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
649930991	377	35.98	3	376	1	361	1.0e-78	286	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
649930993	317	45.4	4	317	1	308	1.0e-94	339	COG0039	Malate/lactate dehydrogenase	313
649930994	742	67.75	1	741	2	742	0.0e+00	1154	COG2838	Monomeric isocitrate dehydrogenase	744
649930996	594	61.03	9	593	1	585	0.0e+00	926	COG0173	Aspartyl-tRNA synthetase	585
649930997	240	35.34	1	229	1	230	6.0e-46	177	COG2186	DNA-binding transcriptional regulator, FadR family	241
649930998	413	32.76	6	411	8	385	5.0e-63	235	COG0247	Fe-S oxidoreductase	388
649930999	457	41.83	8	457	1	456	3.0e-95	342	COG0277	FAD/FMN-containing dehydrogenase	459
649931000	230	43.04	1	230	1	230	6.0e-50	190	COG1346	Putative effector of murein hydrolase	230
649931001	121	39.47	2	115	1	114	1.0e-14	72.1	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
649931003	183	30.56	1	176	38	216	4.0e-19	88.1	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
649931004	711	41.18	4	454	6	459	0.0e+00	467	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
649931006	202	46.24	12	197	7	192	9.0e-47	179	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
649931008	635	45.27	1	633	22	649	0.0e+00	724	COG1166	Arginine decarboxylase (spermidine biosynthesis)	652
649931009	384	28.34	6	356	18	389	1.0e-68	254	COG0019	Diaminopimelate decarboxylase	394
649931010	398	47.39	1	398	1	387	4.0e-113	401	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
649931011	181	29.41	3	103	2	103	4.0e-09	54.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
649931012	443	45.23	4	443	1	436	7.0e-126	444	COG2704	Anaerobic C4-dicarboxylate transporter	436
649931013	471	37.53	11	467	7	452	3.0e-96	345	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649931015	292	35.81	1	283	12	307	5.0e-59	221	COG1161	Ribosome biogenesis GTPase A	322
649931016	742	46.09	50	739	5	664	0.0e+00	684	COG1331	Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains	667
649931017	130	44.54	7	121	3	121	5.0e-29	120	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
649931020	483	27.5	33	452	47	450	1.0e-54	207	COG3303	Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit	501
649931021	455	44.42	12	455	119	558	1.0e-116	413	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
649931024	406	29.29	165	357	46	239	1.0e-11	64.6	COG3063	Tfp pilus assembly protein PilF	250
649931025	112	63.96	3	112	2	112	3.0e-42	163	COG2824	Uncharacterized Zn-ribbon-containing protein	112
649931026	468	36.47	63	319	58	323	2.0e-48	187	COG3344	Retron-type reverse transcriptase	328
649931030	322	25.87	47	321	1	279	2.0e-28	120	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
649931031	1126	33.59	737	986	99	334	1.0e-33	139	COG0642	Signal transduction histidine kinase	336
649931032	113	23.71	1	95	3	97	5.0e-05	40	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
649931034	537	24.62	72	522	43	435	2.0e-39	157	COG3303	Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit	501
649931035	122	40.91	32	119	1	88	1.0e-16	78.7	COG3326	Uncharacterized membrane protein YsdA, DUF1294 family	94
649931037	896	31.3	498	754	85	329	6.0e-35	143	COG0642	Signal transduction histidine kinase	336
649931038	146	33.06	6	128	1	116	6.0e-15	73.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
649931040	1039	26.25	39	345	7	320	1.0e-31	132	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
649931041	222	33.78	1	219	1	221	1.0e-33	136	COG0569	Trk K+ transport system, NAD-binding component	225
649931042	216	34.84	1	214	1	221	3.0e-31	128	COG0569	Trk K+ transport system, NAD-binding component	225
649931043	943	40.64	14	935	22	917	0.0e+00	804	COG0474	Magnesium-transporting ATPase (P-type)	917
649931045	474	32.45	8	474	5	482	3.0e-69	256	COG1233	Phytoene dehydrogenase-related protein	487
649931047	170	37.11	22	161	1	157	4.0e-29	120	COG1225	Peroxiredoxin	157
649931048	145	25.53	9	144	4	142	1.0e-04	39	COG3431	Uncharacterized membrane protein, DUF373 family	142
649931051	157	40.88	11	137	1	134	3.0e-30	124	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
649931053	884	25.07	24	362	9	348	3.0e-30	127	COG3614	Extracellular (periplasmic) sensor domain CHASE1 (specificity unknown)	348
649931061	218	24.35	45	218	5	197	4.0e-18	84.9	COG1335	Nicotinamidase-related amidase	205
649931064	264	31.8	1	251	6	266	1.0e-33	137	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
649931065	266	45.16	51	266	6	222	2.0e-49	189	COG0765	ABC-type amino acid transport system, permease component	222
649931066	243	50.21	1	241	1	240	7.0e-84	303	COG1126	ABC-type polar amino acid transport system, ATPase component	240
649931074	1066	28.46	6	1013	1	952	0.0e+00	497	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
649931075	656	20.59	1	533	1	469	5.0e-18	86.6	COG3593	Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains	581
649931076	411	18.73	21	404	9	390	4.0e-23	102	COG0732	Restriction endonuclease S subunit	391
649931077	539	29.1	13	535	4	487	9.0e-80	291	COG0286	Type I restriction-modification system, DNA methylase subunit	489
649931086	446	32.77	16	301	32	327	1.0e-44	174	COG3344	Retron-type reverse transcriptase	328
649931087	512	28.31	20	326	1	327	7.0e-35	142	COG3344	Retron-type reverse transcriptase	328
649931089	412	22.4	90	390	1	303	5.0e-13	69.2	COG0582	Integrase	309
649931090	334	23.05	86	320	35	284	4.0e-18	86	COG4974	Site-specific recombinase XerD	300
649931096	297	38.44	6	297	14	309	7.0e-56	211	COG4227	Antirestriction protein ArdC	316
649931098	106	38.33	11	70	5	64	4.0e-09	53.3	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
649931100	235	24.58	19	197	23	188	3.0e-18	85.6	COG2114	Adenylate cyclase, class 3	227
649931107	501	23.31	183	493	63	373	1.0e-24	108	COG4938	Predicted ATPase	374
649931108	257	30	18	214	7	201	2.0e-14	73.4	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
649931126	997	21.38	23	983	16	914	6.0e-116	412	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
649931127	347	36.88	116	272	1	159	2.0e-31	130	COG4804	Predicted nuclease of restriction endonuclease-like (RecB) superfamily,  DUF1016 family	159
649931128	459	18.73	25	418	1	390	3.0e-23	103	COG0732	Restriction endonuclease S subunit	391
649931129	710	27.67	6	476	4	415	5.0e-59	222	COG0286	Type I restriction-modification system, DNA methylase subunit	489
649931130	95	28.57	1	54	6	61	2.0e-04	37.6	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
649931131	199	27.81	48	196	4	114	3.0e-11	61.8	COG2105	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family	120
649931143	305	30.69	34	134	20	115	2.0e-12	66.9	COG3628	Phage baseplate assembly protein W	116
649931147	87	44.16	6	82	16	92	8.0e-10	55.3	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
649931152	427	20.83	5	383	4	347	1.0e-20	94.6	COG3500	Phage protein D	350
649931168	798	22.54	52	375	2	326	9.0e-19	89.7	COG3392	Adenine-specific DNA methylase	330
649931178	304	36.15	12	303	7	295	3.0e-54	205	COG4974	Site-specific recombinase XerD	300
649931183	1100	20.2	20	509	15	438	9.0e-23	103	COG0358	DNA primase (bacterial type)	568
649931184	742	31.14	47	721	38	688	9.0e-86	312	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
649931190	194	20.81	18	188	28	174	4.0e-04	38.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649931192	700	23.28	157	363	6	211	3.0e-05	44.5	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
649931196	528	31.38	16	253	2	222	2.0e-26	114	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
649931198	267	65.56	111	261	3	153	1.0e-62	233	COG0691	tmRNA-binding protein	153
649931200	413	32.16	1	381	4	372	9.0e-51	194	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
649931201	134	58.4	3	127	2	126	2.0e-47	181	COG0853	Aspartate 1-decarboxylase	126
649931202	279	52.65	1	277	1	283	1.0e-100	359	COG0414	Panthothenate synthetase	285
649931203	267	61.36	4	267	1	264	8.0e-105	373	COG0413	Ketopantoate hydroxymethyltransferase	268
649931204	663	30	267	605	68	402	6.0e-38	152	COG0840	Methyl-accepting chemotaxis protein	408
649931205	361	42.74	1	360	1	345	4.0e-86	311	COG0205	6-phosphofructokinase	347
649931206	212	27.65	43	211	4	152	3.0e-17	82.2	COG1225	Peroxiredoxin	157
649931209	183	36.07	1	183	5	186	1.0e-27	116	COG3945	Hemerythrin-like domain	189
649931210	435	49.55	1	324	1	333	2.0e-100	359	COG0460	Homoserine dehydrogenase	333
649931211	145	40	1	145	7	149	1.0e-31	128	COG0781	Transcription termination factor NusB	151
649931212	155	66.89	3	153	2	152	2.0e-57	214	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
649931213	400	65.2	1	204	1	203	5.0e-86	311	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
649931214	214	47.5	1	198	1	197	2.0e-62	232	COG0307	Riboflavin synthase alpha chain	204
649931215	374	63.64	2	144	3	145	1.0e-57	217	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
649931216	150	60.67	1	150	1	150	7.0e-52	196	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
649931217	151	56.58	1	147	2	152	2.0e-50	191	COG2131	Deoxycytidylate deaminase	164
649931218	422	22.95	41	393	49	394	9.0e-18	85.3	COG2814	Predicted arabinose efflux permease, MFS family	394
649931219	136	24.79	23	136	17	133	6.0e-05	40	COG2703	Hemerythrin	144
649931221	503	23.14	19	500	5	413	2.0e-26	114	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
649931224	756	53.49	8	739	9	748	0.0e+00	823	COG2183	Transcriptional accessory protein Tex/SPT6	780
649931229	629	41.4	1	551	4	550	0.0e+00	514	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
649931230	342	37.23	1	324	13	334	1.0e-67	250	COG3520	Predicted component of the type VI protein secretion system	335
649931231	598	40.13	1	598	1	621	0.0e+00	498	COG3519	Type VI protein secretion system component VasA	621
649931232	156	38.71	1	154	1	153	3.0e-20	91.2	COG3518	Predicted component of the type VI protein secretion system	157
649931233	165	33.92	1	165	1	162	1.0e-32	132	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
649931234	494	55.65	17	494	18	495	0.0e+00	666	COG3517	Predicted component of the type VI protein secretion system	495
649931235	173	45.83	5	172	2	169	1.0e-44	172	COG3516	Predicted component of the type VI protein secretion system	169
649931238	221	26.94	3	214	41	245	3.0e-21	95.4	COG3455	Type VI protein secretion system component VasF	262
649931239	465	27.11	8	464	7	446	8.0e-48	185	COG3522	Predicted component of the type VI protein secretion system	446
649931240	167	25.74	1	132	1	126	9.0e-07	46.4	COG3521	Predicted component of the type VI protein secretion system	159
649931242	167	41.36	4	163	3	161	2.0e-33	135	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
649931248	144	41.18	7	142	15	148	9.0e-31	126	COG1607	Acyl-CoA hydrolase	157
649931251	103	46.74	12	103	3	94	9.0e-24	101	COG3123	Uncharacterized conserved protein YaiE, UPF0345 family	94
649931253	470	47.69	1	470	1	443	0.0e+00	516	COG0174	Glutamine synthetase	443
649931254	112	74.11	1	112	1	112	6.0e-38	149	COG0347	Nitrogen regulatory protein PII	112
649931255	695	60.52	2	694	30	723	0.0e+00	931	COG3968	Glutamine synthetase type III	724
649931258	86	25.84	1	85	2	90	2.0e-05	40.6	COG2026	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system	90
649931259	826	40.19	7	826	51	845	0.0e+00	676	COG1643	HrpA-like RNA helicase	845
649931260	224	36.44	1	224	1	216	7.0e-35	140	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
649931261	300	17.32	72	295	11	232	1.0e-04	40.6	COG0671	Membrane-associated phospholipid phosphatase	232
649931264	184	32	1	184	2	198	6.0e-23	100	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
649931265	246	36.51	2	245	1	241	1.0e-45	176	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
649931266	358	31.81	3	353	2	364	6.0e-58	218	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
649931268	168	34.06	5	142	13	148	1.0e-20	92.7	COG4957	Predicted transcriptional regulator	148
649931269	262	54.1	1	237	1	244	3.0e-77	282	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
649931270	423	38.76	5	422	1	414	2.0e-96	346	COG2733	Uncharacterized membrane-anchored protein YjiN, DUF445 family	415
649931272	319	64.87	5	319	2	317	0.0e+00	473	COG0825	Acetyl-CoA carboxylase alpha subunit	317
649931273	1156	50	6	1147	4	1136	0.0e+00	1298	COG0587	DNA polymerase III, alpha subunit	1139
649931274	428	45.35	1	406	2	419	0.0e+00	462	COG0124	Histidyl-tRNA synthetase	429
649931275	459	46.58	289	448	19	177	4.0e-35	142	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649931276	786	30.24	476	766	2	272	2.0e-49	191	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
649931280	415	68.63	4	410	7	412	0.0e+00	672	COG0112	Glycine/serine hydroxymethyltransferase	413
649931281	148	53.02	2	148	3	151	2.0e-46	177	COG0698	Ribose 5-phosphate isomerase RpiB	151
649931282	410	61.41	1	410	2	411	0.0e+00	519	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
649931283	77	62.34	1	77	3	79	3.0e-10	56.9	COG0236	Acyl carrier protein	80
649931284	246	55.34	1	244	1	250	2.0e-52	198	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649931285	310	54.37	1	308	1	309	3.0e-94	338	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
649931286	326	58.9	1	326	1	322	5.0e-122	430	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
649931287	352	50.74	1	333	2	338	3.0e-109	388	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
649931288	60	66.67	1	57	1	57	4.0e-15	73	COG0333	Ribosomal protein L32	57
649931289	178	27.12	1	175	2	174	6.0e-15	74.2	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
649931290	293	43.03	38	279	57	305	8.0e-56	210	COG0616	Periplasmic serine protease, ClpP class	317
649931291	154	37.66	1	144	2	155	9.0e-26	109	COG0622	Predicted phosphodiesterase	172
649931294	321	30.43	2	321	4	322	3.0e-33	135	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
649931297	277	43.5	33	276	9	250	2.0e-66	245	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
649931299	134	53.79	1	130	4	135	1.0e-43	168	COG1832	Predicted CoA-binding protein	140
649931302	645	36.98	2	333	1	329	1.0e-77	284	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
649931303	406	32.46	12	406	2	408	5.0e-77	282	COG0004	Ammonia channel protein AmtB	409
649931305	433	49.3	7	428	21	447	0.0e+00	478	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
649931307	336	49.41	6	336	3	339	4.0e-92	331	COG0309	Hydrogenase maturation factor	339
649931308	363	52.47	1	363	1	362	0.0e+00	468	COG0409	Hydrogenase maturation factor	364
649931309	76	49.3	1	69	1	71	4.0e-15	73	COG0298	Hydrogenase maturation factor	82
649931310	758	48.14	9	753	3	748	0.0e+00	838	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
649931311	286	45.41	79	281	1	200	1.0e-65	243	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
649931313	161	34.59	1	158	2	160	3.0e-22	98.1	COG0680	Ni,Fe-hydrogenase maturation factor	160
649931314	559	52.58	1	559	1	545	0.0e+00	651	COG0374	Ni,Fe-hydrogenase I large subunit	545
649931315	447	29.48	4	411	2	386	3.0e-44	173	COG5557	Ni/Fe-hydrogenase 2 integral membrane subunit HybB	401
649931316	308	32.02	40	242	10	191	3.0e-38	152	COG0437	Fe-S-cluster-containing dehydrogenase component	203
649931317	369	49.31	3	362	6	354	1.0e-110	393	COG1740	Ni,Fe-hydrogenase I small subunit	355
649931318	110	42.86	1	109	1	112	6.0e-25	105	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
649931320	458	39.87	10	453	6	453	2.0e-99	356	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649931324	306	38.23	11	294	11	294	4.0e-60	225	COG1162	Putative ribosome biogenesis GTPase RsgA	301
649931326	204	26.05	14	203	5	217	2.0e-17	82.5	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
649931327	738	25.1	468	711	8	242	2.0e-29	124	COG1647	Esterase/lipase	243
649931328	253	36.08	3	249	4	257	2.0e-40	159	COG0584	Glycerophosphoryl diester phosphodiesterase	257
649931329	361	51.99	3	353	5	356	4.0e-113	401	COG3426	Butyrate kinase	358
649931330	154	30.86	3	153	1	161	9.0e-23	99.7	COG3467	Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily	166
649931331	164	33.12	2	161	10	165	1.0e-33	135	COG0835	Chemotaxis signal transduction protein	165
649931332	295	28.31	6	276	15	280	8.0e-32	130	COG5495	Predicted oxidoreductase, contains short-chain dehydrogenase (SDR) and DUF2520 domains	289
649931338	305	48.5	4	293	3	300	7.0e-100	357	COG0031	Cysteine synthase	300
649931339	448	25.5	30	213	10	204	1.0e-08	54.6	COG1994	Zn-dependent protease (includes SpoIVFB)	230
649931349	222	27.37	1	179	1	149	2.0e-15	76.1	COG0262	Dihydrofolate reductase	167
649931350	413	23.31	45	400	41	402	4.0e-37	149	COG3464	Transposase	402
649931361	148	34.69	1	146	3	139	9.0e-10	56.5	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
649931363	369	27.93	19	366	14	358	4.0e-40	159	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
649931364	389	27.25	1	386	1	383	7.0e-46	178	COG5505	Uncharacterized membrane protein	384
649931372	409	21.23	12	399	1	387	2.0e-25	110	COG2814	Predicted arabinose efflux permease, MFS family	394
649931374	301	25	54	269	30	244	2.0e-18	86.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
649931375	446	32.77	16	301	32	327	3.0e-44	173	COG3344	Retron-type reverse transcriptase	328
649931377	1468	22.41	410	1467	239	1278	8.0e-58	220	COG2911	Autotransporter translocation and assembly factor TamB	1278
649931378	612	28.72	37	612	16	594	4.0e-71	262	COG0729	Outer membrane translocation and assembly module TamA	594
649931379	171	24.86	8	170	7	175	4.0e-10	57.7	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
649931380	401	27.39	20	371	18	402	9.0e-41	161	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
649931384	401	38.11	1	401	9	409	8.0e-85	307	COG3876	Uncharacterized conserved protein YbbC, DUF1343 family	409
649931386	321	43.23	12	318	1	287	6.0e-78	284	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
649931387	815	32.06	188	526	1	331	5.0e-44	173	COG0642	Signal transduction histidine kinase	336
649931388	66	62.5	1	63	1	64	2.0e-20	91	COG1278	Cold shock protein, CspA family	67
649931390	252	48.85	118	248	1	131	4.0e-36	145	COG3260	Ni,Fe-hydrogenase III small subunit	148
649931391	503	36.99	141	503	3	367	2.0e-77	283	COG3261	Ni,Fe-hydrogenase III large subunit	382
649931392	477	27.33	1	470	9	485	1.0e-42	167	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
649931393	213	25.82	4	211	7	217	1.0e-15	76.8	COG4237	Hydrogenase-4 membrane subunit HyfE	218
649931394	302	30.72	1	301	7	308	8.0e-38	151	COG0650	Formate hydrogenlyase subunit 4	309
649931395	657	36.16	10	498	1	480	2.0e-55	210	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
649931397	260	32.27	39	255	6	193	1.0e-43	169	COG0437	Fe-S-cluster-containing dehydrogenase component	203
649931398	415	22.91	7	401	3	362	3.0e-20	93.1	COG4881	Predicted membrane protein	371
649931399	667	32.72	25	510	15	486	4.0e-56	213	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
649931400	225	33.1	72	212	2	142	5.0e-17	81.5	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
649931405	297	54.61	6	297	4	296	1.0e-104	372	COG1159	GTPase Era, involved in 16S rRNA processing	298
649931407	224	52.75	1	216	8	225	4.0e-61	227	COG0571	dsRNA-specific ribonuclease	235
649931408	294	38.37	13	257	3	246	9.0e-49	187	COG1414	DNA-binding transcriptional regulator, IclR family	246
649931409	272	36.12	49	266	10	235	3.0e-37	148	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
649931410	74	29.76	2	74	1	84	5.0e-04	36.1	COG1977	Molybdopterin converting factor, small subunit	84
649931413	578	32.59	1	558	5	568	2.0e-93	336	COG2414	Aldehyde:ferredoxin oxidoreductase	614
649931414	477	26.12	71	419	44	416	1.0e-25	111	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
649931415	297	32.42	6	259	1	253	1.0e-32	133	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
649931416	92	40.43	1	92	7	99	1.0e-19	87.7	COG2440	Ferredoxin-like protein FixX	99
649931417	432	32.95	4	432	3	396	9.0e-55	208	COG0644	Dehydrogenase (flavoprotein)	396
649931418	333	34.25	6	328	2	313	6.0e-48	184	COG2025	Electron transfer flavoprotein, alpha subunit	313
649931419	653	43.72	1	362	1	363	5.0e-97	349	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
649931420	347	35.65	13	330	18	340	1.0e-46	180	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649931424	635	28.25	325	634	38	331	4.0e-38	153	COG0642	Signal transduction histidine kinase	336
649931425	466	24.82	5	415	15	389	4.0e-33	136	COG3552	Uncharacterized conserved protein, contains von Willebrand factor type A (vWA) domain	395
649931426	300	25.77	15	294	25	274	1.0e-29	124	COG0714	MoxR-like ATPase	329
649931427	401	39.1	27	401	8	377	2.0e-85	309	COG1454	Alcohol dehydrogenase, class IV	377
649931428	108	28.42	13	107	17	111	7.0e-14	69.2	COG4679	Phage-related protein	116
649931429	109	38.46	45	96	8	58	8.0e-05	39	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
649931430	366	29.21	11	355	11	344	6.0e-33	135	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649931431	465	47.58	10	455	5	457	0.0e+00	477	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649931433	387	40.69	13	387	5	377	4.0e-100	358	COG1454	Alcohol dehydrogenase, class IV	377
649931439	295	36.93	9	291	3	289	8.0e-60	223	COG2048	Heterodisulfide reductase, subunit B	293
649931440	665	50	3	665	2	621	0.0e+00	672	COG1148	Heterodisulfide reductase, subunit A (polyferredoxin)	622
649931441	161	53.91	6	133	1	128	2.0e-47	181	COG1908	Coenzyme F420-reducing hydrogenase, delta subunit	132
649931444	280	29.3	4	274	1	251	6.0e-41	161	COG0543	NAD(P)H-flavin reductase	252
649931447	223	48.58	1	212	2	207	2.0e-61	228	COG0125	Thymidylate kinase	208
649931449	312	47.22	1	251	1	251	3.0e-63	235	COG1774	Cell fate regulator YaaT, PSP1 superfamily (controls sporulation, competence, biofilm development)	265
649931450	509	48.45	1	507	3	547	0.0e+00	632	COG0143	Methionyl-tRNA synthetase	558
649931451	195	25.81	3	178	28	208	5.0e-16	77.9	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
649931452	63	43.1	1	56	1	58	4.0e-13	66.5	COG0227	Ribosomal protein L28	77
649931453	127	48.44	1	127	2	129	6.0e-33	132	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
649931454	716	48.47	1	714	6	701	0.0e+00	872	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
649931455	68	56.25	1	63	1	64	5.0e-11	59.5	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
649931456	202	53.8	5	188	4	186	1.0e-61	229	COG0194	Guanylate kinase	191
649931457	292	38.91	1	292	1	290	8.0e-66	243	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
649931458	328	58.26	4	323	3	323	0.0e+00	460	COG1087	UDP-glucose 4-epimerase	329
649931459	479	52.83	1	473	3	477	0.0e+00	563	COG0469	Pyruvate kinase	477
649931460	198	56.45	13	197	3	188	2.0e-72	265	COG2818	3-methyladenine DNA glycosylase Tag	188
649931465	498	46.84	1	474	2	464	0.0e+00	493	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649931467	323	26.54	68	322	54	305	6.0e-08	52	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
649931470	327	27.09	34	277	22	265	8.0e-14	71.6	COG5607	CHAD domain (function unknown)	283
649931473	1196	37.31	3	385	1	357	6.0e-90	326	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
649931475	290	68.38	1	290	1	291	1.0e-119	422	COG0074	Succinyl-CoA synthetase, alpha subunit	293
649931476	389	59.49	1	388	1	387	0.0e+00	533	COG0045	Succinyl-CoA synthetase, beta subunit	387
649931477	749	46.01	427	748	1	325	6.0e-95	342	COG0280	Phosphotransacetylase	327
649931477	749	58.31	7	430	21	432	0.0e+00	554	COG0281	Malic enzyme	432
649931478	437	53.85	4	414	2	408	4.0e-106	378	COG1301	Na+/H+-dicarboxylate symporter	415
649931479	468	38.78	8	464	4	452	1.0e-99	356	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649931481	661	27.92	283	658	2	387	4.0e-60	226	COG0247	Fe-S oxidoreductase	388
649931482	187	39.61	8	158	3	156	2.0e-33	135	COG1683	Uncharacterized conserved protein YbbK, DUF523 family	156
649931485	700	48.84	4	686	5	687	0.0e+00	710	COG0480	Translation elongation factor EF-G, a GTPase	697
649931487	140	25.76	5	136	3	130	1.0e-12	65.7	COG5015	Uncharacterized protein, pyridoxamine 5'-phosphate oxidase (PNPOx-like) family	132
649931491	93	50.55	1	91	2	91	7.0e-25	105	COG0776	Bacterial nucleoid DNA-binding protein	94
649931492	584	53.19	33	576	4	540	0.0e+00	529	COG0539	Ribosomal protein S1	541
649931493	282	40.97	1	282	2	289	5.0e-79	287	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
649931494	233	50.45	7	227	3	221	5.0e-63	234	COG0283	Cytidylate kinase	222
649931495	429	46.74	9	429	10	427	3.0e-121	428	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
649931496	286	41.75	2	285	1	279	5.0e-72	264	COG0287	Prephenate dehydrogenase	279
649931497	359	52.54	88	358	1	276	3.0e-91	329	COG0077	Prephenate dehydratase	279
649931499	385	17.83	1	382	4	406	1.0e-17	84.6	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649931500	388	20.29	9	386	16	406	1.0e-21	98	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649931501	229	48.43	8	229	1	223	1.0e-75	276	COG1136	ABC-type lipoprotein export system, ATPase component	226
649931502	405	30.47	22	404	6	369	2.0e-24	107	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649931503	93	29.79	1	93	1	93	4.0e-08	49.5	COG1550	Uncharacterized conserved protein YlxP, DUF503 family	95
649931505	357	49.58	6	351	2	352	7.0e-106	377	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
649931506	274	24.91	7	266	12	274	3.0e-29	122	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
649931507	137	25.66	11	118	12	123	3.0e-07	47.7	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
649931508	377	38	121	369	96	334	3.0e-39	156	COG0642	Signal transduction histidine kinase	336
649931509	933	31.71	338	686	1	334	3.0e-43	170	COG0642	Signal transduction histidine kinase	336
649931510	191	28.74	21	187	25	191	1.0e-18	86.5	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
649931511	251	29.89	1	250	1	271	2.0e-34	139	COG0338	Site-specific DNA-adenine methylase	274
649931556	423	28.17	143	422	8	268	5.0e-31	129	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
649931564	279	36.2	7	277	33	296	3.0e-40	158	COG0501	Zn-dependent protease with chaperone function	302
649931565	306	26.88	51	301	1	240	3.0e-35	142	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
649931566	437	38.9	3	437	2	428	3.0e-96	345	COG1253	Hemolysin or related protein, contains CBS domains	429
649931568	401	46.53	1	401	3	400	8.0e-126	443	COG1812	Archaeal S-adenosylmethionine synthetase	400
649931570	457	52.95	1	456	3	459	0.0e+00	565	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649931571	397	30.79	12	392	6	391	5.0e-63	235	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
649931572	162	40.99	2	162	3	151	2.0e-39	155	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
649931575	124	49.59	12	124	1	121	7.0e-32	129	COG2033	Desulfoferrodoxin, superoxide reductase-like (SORL) domain	126
649931576	457	27.76	79	408	10	344	5.0e-44	172	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
649931579	467	41.05	1	467	29	500	2.0e-113	402	COG0513	Superfamily II DNA and RNA helicase	513
649931581	485	35.24	154	481	7	330	2.0e-40	160	COG0642	Signal transduction histidine kinase	336
649931582	226	47.14	5	223	3	228	4.0e-62	231	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649931583	558	33.85	157	501	25	408	2.0e-40	161	COG0840	Methyl-accepting chemotaxis protein	408
649931585	217	46.51	3	128	1	117	3.0e-16	79	COG0517	CBS domain	117
649931587	290	37.06	5	286	8	285	1.0e-56	213	COG0685	5,10-methylenetetrahydrofolate reductase	291
649931588	544	41.01	1	528	3	529	0.0e+00	559	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
649931589	229	31.03	30	228	3	203	6.0e-30	124	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
649931590	329	45.78	1	327	1	326	1.0e-72	267	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
649931592	247	62.66	1	240	1	241	2.0e-97	349	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
649931593	164	56.58	4	155	1	152	5.0e-51	193	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
649931594	199	46.27	1	198	1	201	2.0e-48	185	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
649931595	337	68.58	1	330	1	331	0.0e+00	530	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
649931597	632	43.33	1	532	1	528	0.0e+00	510	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
649931598	186	18.12	17	164	4	152	4.0e-05	41.4	COG5608	LEA14-like dessication related protein	161
649931600	396	72.84	2	395	1	393	0.0e+00	695	COG0133	Tryptophan synthase beta chain	396
649931601	161	52.03	7	153	3	150	4.0e-54	203	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
649931603	194	29.78	19	193	21	196	3.0e-20	91.8	COG3932	Uncharacterized conserved protein	209
649931604	166	46.43	1	164	3	164	1.0e-40	158	COG1592	Rubrerythrin	166
649931607	307	24.78	72	301	19	237	5.0e-31	128	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
649931608	246	24.9	1	239	1	226	5.0e-29	121	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
649931609	637	31.85	28	627	1	562	2.0e-94	340	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
649931610	221	24.55	12	119	22	129	6.0e-03	34.5	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
649931611	368	54.64	5	368	1	366	0.0e+00	505	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
649931614	187	35.33	10	173	4	168	6.0e-31	127	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
649931615	522	43.25	3	503	5	507	2.0e-99	356	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
649931616	107	37.5	1	87	12	99	6.0e-12	62.5	COG0640	DNA-binding transcriptional regulator, ArsR family	110
649931618	389	21.11	193	383	1	192	3.0e-11	63.4	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
649931619	579	40.27	1	567	1	597	0.0e+00	478	COG2414	Aldehyde:ferredoxin oxidoreductase	614
649931620	357	44.94	1	333	2	332	2.0e-99	356	COG0836	Mannose-1-phosphate guanylyltransferase	333
649931621	129	58.1	6	110	22	126	3.0e-28	117	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
649931622	277	49.46	1	272	2	278	4.0e-89	321	COG1091	dTDP-4-dehydrorhamnose reductase	281
649931623	356	59.83	9	353	2	340	0.0e+00	525	COG1088	dTDP-D-glucose 4,6-dehydratase	340
649931624	683	23.05	24	676	46	762	2.0e-63	237	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
649931625	424	45.56	1	417	2	424	2.0e-115	409	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
649931626	208	43.9	3	205	2	205	5.0e-27	114	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
649931627	282	61.62	1	282	1	284	1.0e-120	426	COG0777	Acetyl-CoA carboxylase beta subunit	294
649931628	268	53.99	1	262	1	263	1.0e-87	315	COG0159	Tryptophan synthase alpha chain	265
649931629	734	32.55	350	647	111	405	2.0e-28	121	COG0840	Methyl-accepting chemotaxis protein	408
649931633	176	43.41	2	176	5	186	5.0e-41	160	COG1636	Predicted ATPase, Adenine nucleotide alpha hydrolases (AANH) superfamily	204
649931635	384	22.28	17	371	31	380	4.0e-27	115	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
649931638	680	35.75	141	672	1	510	2.0e-94	340	COG1657	Squalene cyclase	517
649931639	330	27.49	1	327	1	314	6.0e-39	155	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649931640	635	59.24	1	623	1	624	0.0e+00	861	COG1154	Deoxyxylulose-5-phosphate synthase	627
649931641	332	26.47	24	306	15	317	2.0e-27	116	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649931646	503	34.76	65	494	24	463	3.0e-69	256	COG2027	D-alanyl-D-alanine carboxypeptidase	470
649931649	184	39.11	5	179	2	171	6.0e-31	127	COG0431	NAD(P)H-dependent FMN reductase	184
649931651	248	34.18	56	245	6	197	5.0e-26	111	COG0791	Cell wall-associated hydrolase, NlpC family	197
649931655	537	40.75	15	534	11	527	7.0e-121	427	COG0578	Glycerol-3-phosphate dehydrogenase	532
649931656	493	60.48	1	493	4	498	0.0e+00	709	COG0554	Glycerol kinase	499
649931669	393	21	30	390	38	437	3.0e-11	63.3	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
649931670	267	53.38	2	266	1	265	2.0e-74	272	COG0345	Pyrroline-5-carboxylate reductase	266
649931671	94	45.56	1	90	2	91	3.0e-21	93.4	COG1254	Acylphosphatase	92
649931674	557	22.61	37	442	53	471	7.0e-36	145	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649931676	484	30.04	8	483	2	411	1.0e-67	250	COG2195	Di- or tripeptidase	414
649931679	570	27.72	183	485	109	408	2.0e-29	124	COG0840	Methyl-accepting chemotaxis protein	408
649931685	427	68.15	1	425	1	426	0.0e+00	680	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
649931686	495	41.29	3	492	12	514	0.0e+00	468	COG1640	4-alpha-glucanotransferase	520
649931688	616	50.25	10	614	5	589	0.0e+00	628	COG0465	ATP-dependent Zn proteases	596
649931692	427	28.57	31	284	3	243	6.0e-16	79	COG0191	Fructose/tagatose bisphosphate aldolase	286
649931694	157	51.7	13	155	60	204	5.0e-43	167	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
649931695	413	45.01	4	412	3	404	3.0e-117	415	COG4198	Uncharacterized conserved protein, DUF1015 family	405
649931696	268	32.54	103	265	29	197	2.0e-26	113	COG0791	Cell wall-associated hydrolase, NlpC family	197
649931697	371	61.64	126	357	1	231	8.0e-93	334	COG1186	Protein chain release factor B	239
649931698	513	38.29	15	512	17	515	2.0e-95	343	COG0815	Apolipoprotein N-acyltransferase	518
649931700	235	41.53	1	118	6	123	4.0e-21	94.8	COG0818	Diacylglycerol kinase	123
649931701	121	43.75	4	115	36	144	8.0e-27	112	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
649931702	791	32.56	35	753	14	700	1.0e-126	447	COG1480	Membrane-associated HD superfamily phosphohydrolase	700
649931703	429	70.42	1	426	1	422	0.0e+00	679	COG0148	Enolase	423
649931704	303	36.64	1	270	1	289	4.0e-54	205	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
649931705	221	55.24	12	221	1	209	2.0e-67	248	COG2518	Protein-L-isoaspartate O-methyltransferase	209
649931709	75	43.48	7	75	2	70	2.0e-17	81.1	COG3530	Uncharacterized conserved protein, DUF3820 family	71
649931712	486	46.45	22	486	1	432	0.0e+00	496	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
649931713	143	38.64	12	143	10	137	6.0e-23	99	COG1371	SHS2 domain protein implicated in nucleic acid metabolism	137
649931714	104	46.24	17	103	3	94	4.0e-12	63.1	COG3357	Predicted transcriptional regulator containing an HTH domain fused to a Zn-ribbon	97
649931715	242	25	29	240	10	194	1.0e-12	67.3	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
649931716	259	56.92	7	259	1	240	2.0e-100	358	COG1126	ABC-type polar amino acid transport system, ATPase component	240
649931717	339	49.52	131	336	14	221	4.0e-58	218	COG0765	ABC-type amino acid transport system, permease component	222
649931718	264	40.07	1	262	1	272	8.0e-44	170	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
649931719	364	23.77	1	361	1	349	5.0e-27	115	COG0857	BioD-like N-terminal domain of phosphotransacetylase	354
649931720	432	31.01	6	417	5	398	5.0e-59	222	COG1625	Fe-S oxidoreductase, related to NifB/MoaA family	414
649931721	74	46.03	3	64	2	64	3.0e-13	66.9	COG1923	sRNA-binding regulator protein Hfq	77
649931722	304	50	4	301	1	302	1.0e-95	343	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
649931723	665	39.37	3	665	2	638	0.0e+00	581	COG0323	DNA mismatch repair ATPase MutL	638
649931724	300	33.33	10	300	9	313	1.0e-54	207	COG1686	D-alanyl-D-alanine carboxypeptidase	389
649931725	138	45.32	1	137	1	137	9.0e-41	159	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
649931729	303	29.78	24	238	15	232	2.0e-22	99.5	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
649931736	290	26.92	158	287	8	137	3.0e-07	49.4	COG2510	Uncharacterized membrane protein	140
649931739	478	36.15	11	478	4	457	1.0e-106	380	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
649931740	339	24.16	7	272	2	263	8.0e-22	98.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649931742	670	24.48	18	669	5	607	1.0e-40	161	COG4206	Outer membrane cobalamin receptor protein	608
649931746	263	25	25	235	10	228	1.0e-17	83.9	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
649931747	463	27.88	1	462	1	512	2.0e-57	216	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
649931750	1573	31.04	10	853	2	844	1.0e-123	438	COG3899	Predicted ATPase	849
649931754	333	42.17	100	181	3	85	4.0e-13	69.2	COG3860	Uncharacterized protein	89
649931756	565	35.12	1	554	100	639	2.0e-120	426	COG0209	Ribonucleotide reductase alpha subunit	696
649931757	292	33.85	99	291	53	243	6.0e-31	128	COG1360	Flagellar motor protein MotB	244
649931760	209	39.27	5	190	18	206	2.0e-31	129	COG1584	Succinate-acetate transporter protein	207
649931762	140	31.43	1	140	2	131	5.0e-19	87.2	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
649931765	847	29.43	549	845	69	364	4.0e-46	180	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
649931772	78	40.91	1	66	1	66	5.0e-14	69.6	COG1724	Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family	66
649931773	69	43.64	2	56	1	55	6.0e-11	59.2	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
649931774	501	22.91	1	422	2	463	2.0e-30	127	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649931776	491	36.76	50	487	15	449	5.0e-54	205	COG1538	Outer membrane protein TolC	457
649931777	373	28.61	12	357	9	368	6.0e-22	98.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649931778	1026	38.66	2	1015	1	1008	0.0e+00	788	COG0841	Multidrug efflux pump subunit AcrB	1009
649931779	438	32.22	45	422	7	390	1.0e-58	221	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
649931782	1312	16.39	466	748	2	283	1.0e-08	56.3	COG0515	Serine/threonine protein kinase	384
649931786	262	34.43	131	252	1	122	2.0e-20	93.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649931787	416	18.51	13	370	1	335	7.0e-12	65.5	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
649931789	96	27.14	22	91	19	88	2.0e-03	33.8	COG2747	Negative regulator of flagellin synthesis (anti-sigma28 factor)	93
649931790	219	36.59	1	203	1	205	5.0e-42	164	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
649931791	516	71.07	199	516	1	315	0.0e+00	561	COG0519	GMP synthase, PP-ATPase domain/subunit	315
649931792	489	30.77	257	477	1	170	2.0e-33	137	COG0516	IMP dehydrogenase/GMP reductase	170
649931793	356	41.08	6	351	5	350	8.0e-80	290	COG1363	Putative aminopeptidase FrvX	355
649931794	177	20.13	10	167	1	150	1.0e-09	56.4	COG1259	Bifunctional DNase/RNase	151
649931795	441	44.44	4	439	2	436	0.0e+00	485	COG0621	tRNA A37 methylthiotransferase MiaB	437
649931801	87	54.02	1	87	1	87	7.0e-13	65.3	COG0268	Ribosomal protein S20	88
649931802	329	30.24	1	329	1	332	5.0e-48	185	COG1466	DNA polymerase III, delta subunit	334
649931804	824	54.64	1	823	1	814	0.0e+00	1080	COG0495	Leucyl-tRNA synthetase	814
649931807	265	23.17	107	253	13	175	1.0e-03	37.3	COG2203	GAF domain	175
649931808	355	46.96	3	345	1	340	5.0e-88	317	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
649931809	289	40.29	12	281	1	267	8.0e-67	247	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
649931810	645	33.82	323	582	60	334	1.0e-10	61.9	COG1413	HEAT repeat	335
649931812	169	33.99	3	155	13	165	2.0e-30	125	COG0835	Chemotaxis signal transduction protein	165
649931814	266	37.67	117	262	8	153	9.0e-32	130	COG0835	Chemotaxis signal transduction protein	165
649931815	266	35.5	1	259	9	268	7.0e-38	150	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
649931816	684	36.82	9	684	8	714	0.0e+00	517	COG0643	Chemotaxis protein histidine kinase CheA	716
649931819	440	52.27	1	438	2	441	0.0e+00	566	COG1160	Predicted GTPases	444
649931820	101	46.46	3	101	2	98	2.0e-25	107	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
649931821	356	36.21	1	353	4	361	3.0e-92	332	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
649931822	52	66.67	1	51	1	51	4.0e-12	63	COG1773	Rubredoxin	55
649931823	618	60.2	5	594	15	602	0.0e+00	858	COG1274	Phosphoenolpyruvate carboxykinase, GTP-dependent	608
649931824	529	57.56	10	525	8	521	0.0e+00	735	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
649931826	82	38.57	13	82	11	80	8.0e-08	48.5	COG5302	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid	80
649931827	324	46.48	3	323	2	326	1.0e-77	283	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
649931830	291	32.53	3	291	1	289	3.0e-51	195	COG0040	ATP phosphoribosyltransferase	290
649931831	125	50.48	1	105	8	111	8.0e-40	155	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
649931833	265	47.91	1	262	1	263	7.0e-80	290	COG1101	ABC-type uncharacterized transport system, ATPase component	263
649931834	299	41.84	1	294	5	289	5.0e-57	215	COG4120	ABC-type uncharacterized transport system, permease component	293
649931835	331	44.75	2	324	4	322	6.0e-70	257	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
649931837	252	48.79	1	238	1	248	2.0e-65	242	COG3332	Uncharacterized conserved protein, contains NRDE domain	270
649931839	157	44.59	5	151	1	148	2.0e-33	135	COG0782	Transcription elongation factor, GreA/GreB family	151
649931842	671	30.7	5	668	43	765	5.0e-114	405	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
649931843	313	38.61	5	158	7	155	5.0e-26	111	COG0835	Chemotaxis signal transduction protein	165
649931846	289	33.56	1	289	1	294	3.0e-41	162	COG1597	Diacylglycerol kinase family enzyme	301
649931847	446	32.77	16	301	32	327	3.0e-44	173	COG3344	Retron-type reverse transcriptase	328
649931848	819	36.82	299	790	158	641	6.0e-119	422	COG1067	Predicted ATP-dependent protease	647
649931849	205	41.21	8	203	18	215	3.0e-51	195	COG0321	Lipoate-protein ligase B	221
649931850	468	49.02	3	459	2	454	0.0e+00	484	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
649931851	431	45.5	1	430	3	404	1.0e-103	370	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
649931852	897	51.85	11	895	17	904	0.0e+00	1082	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
649931853	125	50.96	16	119	3	106	2.0e-27	114	COG1993	PII-like signaling protein	109
649931854	124	48.39	1	124	2	125	2.0e-20	91.4	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
649931856	937	44.18	2	497	1	487	3.0e-125	443	COG1530	Ribonuclease G or E	487
649931859	265	24.01	8	259	3	279	1.0e-12	67.3	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
649931865	166	39.49	1	155	6	159	1.0e-28	119	COG2030	Acyl dehydratase	159
649931866	191	38.42	1	187	26	212	1.0e-37	149	COG2316	Predicted hydrolase, HD superfamily	212
649931868	648	43.15	1	533	3	529	0.0e+00	516	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
649931869	772	51.83	13	771	10	773	0.0e+00	950	COG0466	ATP-dependent Lon protease, bacterial type	782
649931870	494	26.9	18	494	6	433	6.0e-61	228	COG0612	Predicted Zn-dependent peptidase	438
649931871	497	30.33	64	476	13	432	4.0e-71	262	COG0612	Predicted Zn-dependent peptidase	438
649931873	259	31.15	1	256	4	257	2.0e-38	152	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
649931875	340	38.58	10	331	17	339	3.0e-77	282	COG1559	Cell division protein YceG, involved in septum cleavage	342
649931877	377	27.73	18	372	1	356	1.0e-45	177	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
649931878	827	37.61	475	825	61	408	3.0e-43	170	COG0840	Methyl-accepting chemotaxis protein	408
649931879	548	32.36	1	543	1	540	2.0e-99	356	COG2985	Uncharacterized membrane protein YbjL, putative transporter	544
649931883	240	25.12	9	201	22	218	3.0e-16	78.8	COG4117	Thiosulfate reductase cytochrome b subunit	221
649931887	471	39.57	1	470	4	459	8.0e-115	407	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649931888	769	23.3	353	626	74	334	2.0e-33	137	COG0642	Signal transduction histidine kinase	336
649931889	468	46.45	1	465	5	461	0.0e+00	505	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649931895	305	26.94	28	219	1	177	3.0e-32	132	COG0437	Fe-S-cluster-containing dehydrogenase component	203
649931896	451	24.07	50	410	21	385	3.0e-17	83.1	COG5557	Ni/Fe-hydrogenase 2 integral membrane subunit HybB	401
649931900	822	29.61	1	807	5	914	0.0e+00	545	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
649931901	670	36.46	133	593	3	457	2.0e-91	330	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
649931902	544	26.92	10	537	1	525	5.0e-54	205	COG1315	Uncharacterized conserved protein, DUF342 family	543
649931903	204	47.78	1	203	2	201	7.0e-51	193	COG0237	Dephospho-CoA kinase	201
649931904	260	40.49	12	258	1	246	7.0e-60	223	COG1414	DNA-binding transcriptional regulator, IclR family	246
649931906	69	43.94	1	65	3	68	5.0e-13	66	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
649931907	260	61.78	1	259	1	259	5.0e-109	387	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
649931908	219	44.12	9	211	4	206	5.0e-55	207	COG0352	Thiamine monophosphate synthase	211
649931909	317	43.23	8	310	3	305	3.0e-94	338	COG1242	Radical SAM superfamily enzyme	312
649931910	218	47.89	9	218	53	263	3.0e-68	251	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
649931912	276	21.33	1	269	11	309	2.0e-16	80.1	COG0226	ABC-type phosphate transport system, periplasmic component	318
649931913	149	23.42	41	148	40	150	7.0e-09	53.4	COG1728	Uncharacterized protein YaaR, TM1646/DUF327 family	151
649931914	66	65.15	1	65	1	66	6.0e-21	92.1	COG1278	Cold shock protein, CspA family	67
649931915	913	29.5	6	880	1	735	0.0e+00	642	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
649931916	687	49.28	1	686	2	690	0.0e+00	772	COG0751	Glycyl-tRNA synthetase, beta subunit	691
649931917	292	75.43	1	289	4	296	0.0e+00	552	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
649931918	468	41.05	1	453	1	454	3.0e-117	415	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
649931919	345	35.82	5	313	17	350	4.0e-64	238	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
649931922	256	26.47	53	253	5	206	4.0e-26	111	COG1852	Uncharacterized protein	209
649931923	314	54.25	4	307	2	307	5.0e-117	414	COG0223	Methionyl-tRNA formyltransferase	307
649931924	171	49.69	1	161	2	164	9.0e-51	192	COG0242	Peptide deformylase	168
649931928	117	25	10	117	15	125	2.0e-07	47.6	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
649931930	434	27.52	17	414	11	376	5.0e-51	195	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
649931931	276	39.62	15	274	1	264	9.0e-60	224	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
649931932	424	33.43	40	395	64	399	3.0e-36	146	COG0840	Methyl-accepting chemotaxis protein	408
649931933	150	27.08	6	141	20	163	1.0e-13	69.6	COG0835	Chemotaxis signal transduction protein	165
649931935	549	36.45	39	549	196	706	5.0e-109	388	COG0643	Chemotaxis protein histidine kinase CheA	716
649931936	199	36.92	5	198	6	200	8.0e-25	106	COG1776	Chemotaxis protein CheY-P-specific phosphatase CheC	203
649931937	236	25.32	1	236	2	211	3.0e-21	95.8	COG2834	Outer membrane lipoprotein-sorting protein	211
649931938	161	56.52	1	160	4	164	4.0e-45	173	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
649931939	448	42.02	6	447	2	436	2.0e-125	443	COG0621	tRNA A37 methylthiotransferase MiaB	437
649931940	139	46.55	3	118	4	117	6.0e-16	76.6	COG1734	RNA polymerase-binding transcription factor DksA	120
649931942	255	35.2	8	252	2	241	3.0e-37	148	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
649931944	609	38.49	5	286	8	311	2.0e-71	264	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
649931945	552	40.41	314	551	72	310	1.0e-53	204	COG1227	Inorganic pyrophosphatase/exopolyphosphatase	311
649931946	203	32.16	1	196	3	199	4.0e-34	137	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
649931947	214	54.82	1	214	8	235	1.0e-69	256	COG0176	Transaldolase	239
649931948	78	42.11	37	73	4	41	2.0e-03	33.8	COG3350	Uncharacterized conserved protein, YHS domain	53
649931949	162	54.9	5	157	4	154	1.0e-45	175	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
649931951	133	43.28	1	130	4	136	3.0e-36	143	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
649931952	326	45.23	4	323	1	317	5.0e-78	284	COG0611	Thiamine monophosphate kinase	317
649931953	815	57.67	7	786	1	781	0.0e+00	1060	COG0466	ATP-dependent Lon protease, bacterial type	782
649931954	146	30.77	7	146	8	146	1.0e-16	78.9	COG0071	Molecular chaperone IbpA, HSP20 family	146
649931957	733	25.63	348	581	1	232	2.0e-10	61.5	COG2202	PAS domain	232
649931958	286	44.69	14	286	3	272	2.0e-84	306	COG2107	Predicted periplasmic solute-binding protein	272
649931959	243	29.52	1	208	3	200	2.0e-21	96.2	COG0775	Nucleoside phosphorylase	234
649931961	638	29.42	26	609	35	563	5.0e-78	286	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
649931962	520	51.8	16	513	1	500	0.0e+00	556	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649931963	400	43.5	1	400	1	397	6.0e-91	327	COG1459	Type II secretory pathway, component PulF	397
649931964	105	24.66	4	74	8	79	6.0e-04	36	COG1669	Predicted nucleotidyltransferase	97
649931965	147	42.07	6	144	5	149	5.0e-21	93.6	COG2165	Type II secretory pathway, pseudopilin PulG	149
649931966	174	23.74	8	145	3	141	3.0e-09	55	COG4970	Tfp pilus assembly protein FimT	181
649931967	114	17.36	2	111	8	125	3.0e-04	37.3	COG2165	Type II secretory pathway, pseudopilin PulG	149
649931968	218	20.85	11	216	3	194	1.0e-08	53.8	COG4795	Type II secretory pathway, component PulJ	194
649931969	310	24.39	1	275	1	279	5.0e-25	108	COG3156	Type II secretory pathway, component PulK	323
649931970	428	16.45	44	422	39	390	1.0e-09	57.7	COG3297	Type II secretory pathway, component PulL	390
649931973	244	64.58	1	240	2	240	8.0e-112	396	COG1126	ABC-type polar amino acid transport system, ATPase component	240
649931974	271	37.87	1	262	1	272	9.0e-44	170	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
649931977	104	27.55	7	104	2	99	6.0e-06	42.6	COG4980	Gas vesicle protein	115
649931978	447	27.3	31	303	14	295	4.0e-36	146	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
649931981	265	31.51	32	264	1	234	6.0e-34	138	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
649931983	180	30	70	178	4	109	2.0e-09	55.3	COG0607	Rhodanese-related sulfurtransferase	110
649931985	193	45.45	1	192	3	200	3.0e-39	154	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
649931986	342	23.2	43	342	15	312	3.0e-13	69.7	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
649931987	284	39.35	4	275	61	332	1.0e-56	213	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
649931988	357	36.57	41	346	2	284	6.0e-57	214	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
649931989	871	55.27	6	863	1	786	0.0e+00	943	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
649931992	521	44.1	3	481	1	475	1.0e-126	447	COG0297	Glycogen synthase	487
649931993	680	59.97	1	680	1	702	0.0e+00	761	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
649931994	426	37.87	60	423	65	421	2.0e-70	259	COG3875	Nickel-dependent lactate racemase	423
649931995	458	40.09	9	458	1	457	2.0e-100	359	COG0277	FAD/FMN-containing dehydrogenase	459
649931996	446	29.65	29	446	1	387	2.0e-61	230	COG0247	Fe-S oxidoreductase	388
649931997	574	35.15	36	556	12	507	1.0e-101	364	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
649931998	1015	24.7	86	670	4	446	5.0e-40	160	COG0439	Biotin carboxylase	449
649931999	550	61.97	7	548	2	548	0.0e+00	691	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
649932005	440	35.85	11	365	5	352	2.0e-66	247	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
649932006	432	59.77	1	430	1	430	0.0e+00	631	COG0104	Adenylosuccinate synthase	430
649932014	218	54.79	1	218	1	217	2.0e-65	242	COG3155	Enhancing lycopene biosynthesis protein 2	217
649932015	195	22.33	4	192	1	213	2.0e-05	42.6	COG3047	Outer membrane protein W	213
649932016	559	24.31	31	520	4	479	1.0e-40	161	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649932017	85	28.4	1	81	3	79	3.0e-06	43.4	COG0236	Acyl carrier protein	80
649932019	327	30.65	20	325	3	305	6.0e-41	161	COG0010	Arginase family enzyme	305
649932020	385	45.1	5	385	1	388	1.0e-82	300	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
649932021	523	29.73	1	521	10	525	2.0e-80	293	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
649932022	183	32.4	6	183	1	178	5.0e-49	187	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
649932023	436	50.23	1	435	2	436	5.0e-101	361	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
649932027	202	20.96	34	197	30	195	1.0e-15	76.2	COG5661	Predicted secreted Zn-dependent protease	210
649932028	428	21.39	46	405	46	392	3.0e-05	43.3	COG2814	Predicted arabinose efflux permease, MFS family	394
649932029	584	32.97	135	584	3	416	1.0e-61	231	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
649932032	395	25.88	6	393	2	378	1.0e-39	157	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
649932034	589	38.64	88	394	1	297	5.0e-85	309	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
649932040	307	37.7	5	305	10	301	1.0e-64	240	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
649932042	254	50	7	246	3	244	1.0e-80	292	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
649932043	438	40.35	4	288	1	274	7.0e-57	214	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
649932044	446	32.77	16	301	32	327	3.0e-44	173	COG3344	Retron-type reverse transcriptase	328
649932045	259	37.24	1	259	2	291	4.0e-60	224	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
649932046	389	26.78	35	386	47	394	1.0e-24	107	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
649932047	1004	27.15	571	865	58	336	4.0e-28	121	COG0642	Signal transduction histidine kinase	336
649932052	315	21.9	17	312	12	296	2.0e-20	93.4	COG2040	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)	300
649932053	520	24.02	202	519	19	341	5.0e-24	106	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649932055	320	38.46	5	313	12	322	2.0e-78	286	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
649932056	257	22.26	1	250	7	258	1.0e-17	84.1	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
649932059	319	26.99	10	296	7	289	8.0e-11	61.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
649932060	256	28.69	136	256	1	122	3.0e-17	82.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649932062	139	36.51	2	64	1	63	6.0e-09	53.5	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
649932066	340	19.17	9	266	24	268	5.0e-07	48.9	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
649932067	446	32.77	16	301	32	327	3.0e-44	173	COG3344	Retron-type reverse transcriptase	328
649932069	174	28.81	3	118	15	132	5.0e-21	94.3	COG4190	Predicted transcriptional regulator	144
649932073	297	34.44	65	296	74	312	5.0e-36	145	COG0657	Acetyl esterase/lipase	312
649932074	341	22.81	96	323	15	221	5.0e-14	72.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
649932076	348	34.01	7	339	4	350	5.0e-76	278	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
649932077	193	21.23	1	179	8	179	4.0e-12	64.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649932078	211	35.44	2	203	5	201	9.0e-36	143	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
649932079	416	28.01	3	350	1	354	4.0e-36	146	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
649932081	95	48.39	1	93	2	93	1.0e-22	98.1	COG2929	Uncharacterized conserved protein, DUF497 family	93
649932082	1032	31.44	1	1027	3	1056	0.0e+00	687	COG0587	DNA polymerase III, alpha subunit	1139
649932083	743	30.59	463	712	101	336	2.0e-36	148	COG0642	Signal transduction histidine kinase	336
649932084	384	55.56	1	324	1	323	1.0e-98	353	COG0206	Cell division GTPase FtsZ	338
649932085	412	51.32	4	412	2	418	6.0e-122	431	COG0849	Cell division ATPase FtsA	418
649932086	274	25	7	272	12	255	4.0e-21	95.5	COG1589	Cell division septal protein FtsQ	269
649932087	305	45.43	7	302	1	317	2.0e-75	275	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
649932088	301	44.17	22	300	6	288	4.0e-74	271	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
649932089	461	57.39	1	457	3	459	0.0e+00	577	COG0773	UDP-N-acetylmuramate-alanine ligase	459
649932090	359	42.74	1	356	1	353	5.0e-90	324	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
649932091	367	44.2	7	364	14	373	2.0e-81	296	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
649932092	453	43.56	3	449	5	448	4.0e-125	442	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
649932093	358	44.93	20	358	1	316	4.0e-59	222	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
649932094	469	46.41	3	458	2	450	4.0e-114	405	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
649932095	505	43.52	18	504	5	475	2.0e-124	439	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
649932096	654	40.23	3	564	7	598	3.0e-130	459	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
649932097	111	22.08	34	110	27	103	6.0e-04	36.4	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
649932098	312	55.13	1	312	2	312	4.0e-115	407	COG0275	16S rRNA C1402 N4-methylase RsmH	314
649932099	160	32.5	1	160	1	146	6.0e-25	106	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
649932103	238	27.43	1	237	2	238	4.0e-22	98.4	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
649932106	374	46.26	5	374	5	377	8.0e-110	390	COG0116	23S rRNA G2445 N2-methylase RlmL	381
649932107	429	36.36	248	417	1	176	3.0e-33	136	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649932108	260	28.26	11	232	6	235	1.0e-28	119	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
649932109	601	65.28	1	601	1	602	0.0e+00	951	COG1217	Predicted membrane GTPase involved in stress response	603
649932112	378	45.16	4	282	5	278	2.0e-70	259	COG2006	Uncharacterized conserved protein, DUF362 family	293
649932113	292	47.64	1	290	5	300	3.0e-87	315	COG4974	Site-specific recombinase XerD	300
649932115	532	43.41	7	520	2	501	0.0e+00	516	COG0427	Acyl-CoA hydrolase	501
649932116	693	33.51	142	523	32	408	1.0e-54	208	COG0840	Methyl-accepting chemotaxis protein	408
649932118	155	45.16	1	155	1	155	5.0e-37	146	COG2193	Bacterioferritin (cytochrome b1)	157
649932119	426	39.72	5	405	12	434	4.0e-87	315	COG2233	Xanthine/uracil permease	451
649932120	209	55.71	1	209	2	210	4.0e-72	264	COG0035	Uracil phosphoribosyltransferase	210
649932121	276	25.96	46	243	16	216	3.0e-11	62.8	COG0705	Membrane associated serine protease, rhomboid family	228
649932122	363	42.74	11	361	31	408	7.0e-89	321	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
649932123	406	42.41	1	404	1	404	3.0e-105	375	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
649932124	320	57.72	3	320	1	324	0.0e+00	460	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
649932125	351	44.99	15	348	5	353	2.0e-103	369	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
649932126	227	34.39	3	189	1	189	2.0e-19	89.6	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
649932127	508	38.41	35	482	5	454	5.0e-113	401	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
649932130	216	42.86	3	212	1	208	2.0e-51	195	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649932134	2763	28.06	2367	2761	10	417	3.0e-42	169	COG4995	Uncharacterized conserved protein, contains CHAT domain	420
649932138	206	25.63	1	198	3	201	3.0e-11	62	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649932139	483	31.93	42	464	8	423	3.0e-66	246	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
649932140	229	52.02	1	221	1	223	1.0e-79	289	COG1136	ABC-type lipoprotein export system, ATPase component	226
649932141	850	25.37	543	850	80	408	3.0e-21	98	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649932142	268	18.22	1	258	1	198	5.0e-04	38.8	COG2834	Outer membrane lipoprotein-sorting protein	211
649932148	733	74.52	5	730	16	729	0.0e+00	1211	COG0376	Catalase (peroxidase I)	730
649932149	407	23.61	98	398	77	377	2.0e-22	100	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649932151	732	25.22	1	710	2	765	7.0e-75	275	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
649932152	237	30.87	9	235	10	197	1.0e-35	143	COG0437	Fe-S-cluster-containing dehydrogenase component	203
649932153	463	22.46	41	441	17	392	4.0e-26	113	COG5557	Ni/Fe-hydrogenase 2 integral membrane subunit HybB	401
649932159	139	21.54	5	122	2	130	3.0e-03	34.3	COG1848	Predicted nucleic acid-binding protein, contains PIN domain	140
649932166	508	30.23	4	295	23	323	4.0e-44	173	COG3344	Retron-type reverse transcriptase	328
649932168	187	41.22	1	131	3	131	2.0e-29	122	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
649932169	65	55.56	2	64	6	68	3.0e-15	73.3	COG2501	Ribosome-associated protein YbcJ, S4-like RNA binding protein	73
649932170	101	48.51	1	101	6	103	2.0e-20	91	COG0023	Translation initiation factor 1 (eIF-1/SUI1)	104
649932172	359	21.43	26	354	25	292	2.0e-20	93.6	COG1234	Ribonuclease BN, tRNA processing enzyme	292
649932173	110	23.89	1	108	3	115	1.0e-10	57.9	COG1917	Cupin domain protein related to quercetin dioxygenase	131
649932174	339	62.2	1	325	3	330	0.0e+00	520	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
649932175	512	56.1	7	252	2	243	2.0e-86	313	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
649932176	318	55.41	4	306	2	306	2.0e-106	379	COG0181	Porphobilinogen deaminase	307
649932177	433	51.42	1	420	1	412	2.0e-124	439	COG0373	Glutamyl-tRNA reductase	414
649932178	271	31.91	3	270	1	279	4.0e-25	108	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
649932179	224	46.06	1	165	1	165	8.0e-40	157	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
649932181	170	20.89	26	167	1	155	2.0e-11	62.2	COG1225	Peroxiredoxin	157
649932182	45	32.56	1	43	1	43	9.0e-05	38.8	COG5510	Predicted small secreted protein	44
649932183	391	34.32	120	383	16	283	8.0e-47	181	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
649932184	848	30.49	24	791	5	750	0.0e+00	522	COG0058	Glucan phosphorylase	750
649932188	475	30.54	145	475	1	329	1.0e-45	177	COG0642	Signal transduction histidine kinase	336
649932189	226	44.05	5	225	3	228	4.0e-59	221	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649932190	192	39.89	1	162	40	218	1.0e-34	139	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
649932191	474	21.51	26	396	29	450	3.0e-24	106	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649932201	185	39.78	6	183	5	185	2.0e-40	158	COG1704	Uncharacterized conserved protein	185
649932207	230	30	37	228	1	198	6.0e-16	77.7	COG2202	PAS domain	232
649932211	484	34.38	199	481	79	335	5.0e-39	155	COG0642	Signal transduction histidine kinase	336
649932213	347	39.66	1	345	1	343	1.0e-79	289	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
649932214	855	28.26	1	718	2	714	2.0e-110	394	COG0643	Chemotaxis protein histidine kinase CheA	716
649932216	176	34.51	27	165	12	153	2.0e-21	95.7	COG0835	Chemotaxis signal transduction protein	165
649932217	497	32.73	7	283	1	268	4.0e-56	212	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
649932218	154	34.03	6	147	19	162	2.0e-21	95.4	COG0835	Chemotaxis signal transduction protein	165
649932220	1480	27.34	300	1133	2	842	2.0e-87	318	COG3899	Predicted ATPase	849
649932224	155	47.74	1	155	1	155	8.0e-35	139	COG2193	Bacterioferritin (cytochrome b1)	157
649932225	271	30.57	3	262	27	291	2.0e-33	136	COG0668	Small-conductance mechanosensitive channel	316
649932227	249	41.94	13	198	15	192	1.0e-35	143	COG3647	Uncharacterized membrane protein YjdF	205
649932229	199	19.8	1	198	1	199	8.0e-05	40.8	COG3637	Opacity protein and related surface antigens	199
649932231	165	18.67	1	163	1	137	9.0e-06	43.3	COG0848	Biopolymer transport protein ExbD	137
649932232	166	23.78	1	143	1	125	1.0e-09	56	COG0848	Biopolymer transport protein ExbD	137
649932233	211	25.76	8	204	16	210	5.0e-16	77.7	COG0811	Biopolymer transport protein ExbB/TolQ	216
649932244	401	23.7	1	360	2	380	9.0e-26	111	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649932245	582	24.7	251	582	1	316	8.0e-24	105	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649932246	319	26.23	19	313	5	303	2.0e-25	110	COG4261	Predicted acyltransferase, LPLAT superfamily	309
649932248	496	37.11	67	254	67	257	9.0e-30	125	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
649932249	397	20.69	12	293	3	278	1.0e-17	84.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649932252	394	37.78	7	389	5	409	3.0e-73	269	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
649932253	84	35.37	1	82	4	79	2.0e-05	40.7	COG0236	Acyl carrier protein	80
649932254	492	26.27	21	452	19	462	2.0e-40	160	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649932255	454	22.95	15	447	26	486	7.0e-26	112	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649932257	375	32.85	1	374	2	412	6.0e-60	225	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
649932258	153	26.12	13	145	1	133	3.0e-20	91.5	COG0824	Acyl-CoA thioesterase FadM	137
649932261	791	22.6	39	784	33	782	2.0e-40	161	COG4258	Predicted exporter	788
649932262	204	26.89	1	204	6	197	6.0e-14	70.8	COG2834	Outer membrane lipoprotein-sorting protein	211
649932263	151	29.08	3	137	2	142	4.0e-07	47.7	COG4706	Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain	161
649932264	528	42.04	6	514	3	491	0.0e+00	489	COG2986	Histidine ammonia-lyase	498
649932265	436	34.81	18	434	21	435	1.0e-66	247	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
649932266	248	27.84	8	194	1	190	7.0e-15	74.6	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
649932267	87	32.1	1	81	1	80	8.0e-06	41.8	COG0236	Acyl carrier protein	80
649932268	409	38.83	4	408	3	411	1.0e-84	307	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
649932269	406	39.27	1	403	2	409	2.0e-90	326	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
649932270	242	45.42	1	239	2	249	4.0e-44	171	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649932273	420	58.81	1	419	4	422	0.0e+00	503	COG2379	Glycerate-2-kinase	422
649932278	224	46.96	1	224	1	229	3.0e-58	218	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649932279	495	34.21	137	471	3	334	9.0e-42	164	COG0642	Signal transduction histidine kinase	336
649932281	633	22.12	36	633	38	646	2.0e-50	194	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
649932283	251	54.25	6	249	3	249	2.0e-72	266	COG1691	NCAIR mutase (PurE)-related protein	254
649932284	385	43.81	2	385	1	383	6.0e-100	357	COG1641	Uncharacterized conserved protein, DUF111 family	387
649932285	149	42.14	9	145	21	159	1.0e-23	102	COG1267	Phosphatidylglycerophosphatase A	160
649932286	414	41.2	1	244	2	249	2.0e-62	233	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
649932288	338	65.16	1	284	1	279	8.0e-89	320	COG0468	RecA/RadA recombinase	279
649932289	386	58.76	1	354	3	353	6.0e-130	457	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
649932290	153	37.5	2	153	18	166	2.0e-17	82.3	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
649932291	875	55.8	1	874	6	875	0.0e+00	1088	COG0013	Alanyl-tRNA synthetase	879
649932292	379	31.73	132	379	96	335	5.0e-35	142	COG0642	Signal transduction histidine kinase	336
649932293	292	53.7	23	290	2	263	7.0e-82	297	COG0548	Acetylglutamate kinase	265
649932294	397	53.25	1	397	4	399	0.0e+00	533	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
649932295	303	55.23	1	302	5	309	9.0e-125	439	COG0078	Ornithine carbamoyltransferase	310
649932296	406	53.22	3	404	1	402	0.0e+00	575	COG0137	Argininosuccinate synthase	403
649932297	151	30.7	21	134	12	125	4.0e-17	80.8	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
649932299	458	61.32	2	456	1	455	0.0e+00	648	COG0165	Argininosuccinate lyase	459
649932301	95	50.53	1	95	1	95	1.0e-23	101	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
649932302	485	54.56	1	484	2	475	0.0e+00	535	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
649932303	480	62.45	1	479	4	481	0.0e+00	737	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
649932304	346	60.23	1	345	1	345	0.0e+00	463	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
649932305	1072	35.6	65	1025	16	955	0.0e+00	685	COG1391	Glutamine synthetase adenylyltransferase	963
649932306	134	41.54	1	129	8	135	8.0e-31	125	COG0824	Acyl-CoA thioesterase FadM	137
649932307	175	37.95	5	168	3	165	3.0e-32	131	COG0597	Lipoprotein signal peptidase	167
649932308	925	51.69	1	925	1	930	0.0e+00	1190	COG0060	Isoleucyl-tRNA synthetase	933
649932309	606	36.39	12	606	18	627	0.0e+00	501	COG3158	K+ transporter	627
649932310	605	36.08	1	605	8	627	0.0e+00	513	COG3158	K+ transporter	627
649932312	258	34.88	7	249	9	258	2.0e-37	149	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
649932313	822	25.92	351	732	31	407	5.0e-32	133	COG0840	Methyl-accepting chemotaxis protein	408
649932314	409	29.41	275	408	8	134	7.0e-20	92	COG1765	Uncharacterized OsmC-related protein	137
649932317	738	45.43	27	736	4	653	0.0e+00	718	COG0370	Fe2+ transport system protein B	653
649932318	75	42.67	1	75	1	75	5.0e-14	69.5	COG1918	Fe2+ transport system protein FeoA	75
649932320	161	28.46	25	141	5	133	2.0e-10	59.1	COG1225	Peroxiredoxin	157
649932321	216	49.32	5	216	1	221	3.0e-73	268	COG1136	ABC-type lipoprotein export system, ATPase component	226
649932322	388	25.74	13	388	4	408	2.0e-25	110	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649932323	428	19.25	1	424	6	405	9.0e-20	91.9	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649932324	489	32.24	1	422	1	405	2.0e-64	240	COG4393	Uncharacterized membrane protein	405
649932325	177	60	1	174	1	175	2.0e-60	225	COG3470	Uncharacterized protein probably involved in high-affinity Fe2+ transport	179
649932326	653	33.8	288	644	32	383	7.0e-52	199	COG0672	High-affinity Fe2+/Pb2+ permease	383
649932327	477	22.15	198	477	116	439	3.0e-20	93.5	COG3659	Carbohydrate-selective porin OprB	439
649932328	147	41.67	13	144	12	142	4.0e-28	116	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
649932330	334	31.33	7	331	1	325	7.0e-52	197	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
649932331	373	32.88	9	369	8	371	3.0e-63	236	COG2843	Poly-gamma-glutamate biosynthesis protein CapA/YwtB (capsule formation), metallophosphatase superfamily	372
649932333	197	26.7	21	187	25	199	4.0e-14	71.5	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
649932334	508	52.53	14	507	1	490	0.0e+00	589	COG0606	Predicted ATPase with chaperone activity	490
649932335	316	52.72	5	315	3	304	2.0e-97	348	COG0492	Thioredoxin reductase	305
649932337	335	39.52	1	291	8	296	2.0e-66	245	COG1230	Co/Zn/Cd efflux system component	296
649932338	402	54.68	1	338	6	347	5.0e-107	381	COG1171	Threonine dehydratase	347
649932339	598	57.93	1	595	1	589	0.0e+00	747	COG0514	Superfamily II DNA helicase RecQ	590
649932340	223	37.63	5	190	7	197	2.0e-24	106	COG3222	Uncharacterized conserved protein, glycosyltransferase A (GT-A) superfamily, DUF2064 family	211
649932341	268	39.36	12	267	4	284	1.0e-63	236	COG1469	GTP cyclohydrolase FolE2	289
649932342	229	53.51	1	225	1	222	4.0e-72	264	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
649932343	583	57.43	299	583	47	342	5.0e-87	315	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
649932344	585	37.23	3	547	1	533	4.0e-105	376	COG0358	DNA primase (bacterial type)	568
649932345	186	26.92	1	129	1	129	2.0e-11	62.2	COG1286	Uncharacterized membrane protein, required for colicin V production	182
649932346	147	54.05	1	147	1	148	5.0e-33	133	COG1610	Uncharacterized conserved protein YqeY	148
649932347	65	58.06	1	62	1	62	2.0e-04	37.6	COG0828	Ribosomal protein S21	67
649932348	109	53.49	12	97	4	89	3.0e-25	106	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
649932349	252	68.24	1	252	1	255	7.0e-118	416	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
649932350	243	55.46	1	238	2	237	4.0e-80	290	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
649932351	207	56.52	1	207	3	203	6.0e-82	296	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
649932352	195	58.97	1	195	2	195	1.0e-77	282	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
649932353	429	53.73	16	428	10	422	0.0e+00	552	COG0141	Histidinol dehydrogenase	425
649932354	212	50.23	3	212	1	213	9.0e-58	216	COG0040	ATP phosphoribosyltransferase	290
649932355	421	63.1	1	417	1	420	0.0e+00	599	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
649932356	286	44.44	10	286	3	278	2.0e-68	252	COG2890	Methylase of polypeptide chain release factors	280
649932357	359	64.17	1	357	3	362	0.0e+00	533	COG0216	Protein chain release factor A	363
649932358	301	44.59	3	297	7	309	3.0e-83	302	COG3872	Uncharacterized conserved protein YqhQ	318
649932359	229	37.04	11	207	31	242	1.0e-41	162	COG1351	Thymidylate synthase ThyX	273
649932360	73	52	1	71	1	75	1.0e-20	91.5	COG0254	Ribosomal protein L31	75
649932361	415	74.34	1	415	4	420	0.0e+00	712	COG1158	Transcription termination factor Rho	422
649932363	280	28.72	1	272	1	284	1.0e-36	146	COG1408	Predicted phosphohydrolase, MPP superfamily	284
649932365	307	28.26	20	152	1	137	1.0e-04	40.6	COG2510	Uncharacterized membrane protein	140
649932367	406	27.91	19	228	25	236	7.0e-15	75.4	COG3063	Tfp pilus assembly protein PilF	250
649932370	332	32.82	7	325	1	314	1.0e-47	184	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649932371	369	48.03	21	366	17	370	3.0e-97	348	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649932372	614	23.15	364	575	3	214	2.0e-15	77.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649932373	1523	34.01	625	864	5	248	6.0e-38	154	COG1216	Glycosyltransferase, GT2 family	305
649932374	1104	35.07	77	617	69	617	4.0e-94	340	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
649932375	598	36.38	47	588	71	616	5.0e-101	362	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
649932376	131	21.05	10	122	6	115	3.0e-07	47.7	COG5442	Flagellar biosynthesis regulator FlaF	115
649932377	129	26.36	1	127	3	130	9.0e-19	85.8	COG5443	Flagellar biosynthesis regulator FlbT	148
649932381	1442	31.92	902	1152	1	260	1.0e-17	86.6	COG0457	Tetratricopeptide (TPR) repeat	291
649932383	254	32.93	1	248	1	244	2.0e-48	185	COG1360	Flagellar motor protein MotB	244
649932384	254	43.9	1	245	1	246	2.0e-67	249	COG1291	Flagellar motor component MotA	266
649932385	85	49.09	1	55	1	55	2.0e-12	64.5	COG1582	Uncharacterized protein YlzI, FlbEa/FlbD family	67
649932386	306	22.35	1	306	1	358	2.0e-20	93.6	COG1344	Flagellin and related hook-associated protein FlgL	360
649932389	100	24	1	100	4	93	3.0e-03	33.4	COG2747	Negative regulator of flagellin synthesis (anti-sigma28 factor)	93
649932391	371	53.46	14	371	8	365	3.0e-108	385	COG1706	Flagellar basal body P-ring protein FlgI	365
649932392	233	38.96	13	230	2	230	1.0e-42	166	COG2063	Flagellar basal body L-ring protein FlgH	230
649932394	262	54.51	1	262	1	265	3.0e-78	284	COG4786	Flagellar basal body rod protein FlgG	265
649932395	238	41.35	1	236	1	265	1.0e-49	189	COG4786	Flagellar basal body rod protein FlgG	265
649932396	250	39.3	22	248	27	246	1.0e-46	180	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
649932397	305	34.84	38	277	3	238	9.0e-41	160	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
649932398	478	28.87	1	478	11	398	4.0e-58	219	COG1419	Flagellar biosynthesis GTPase FlhF	407
649932399	692	52.92	15	690	16	696	0.0e+00	819	COG1298	Flagellar biosynthesis pathway, component FlhA	696
649932401	302	51.33	2	301	6	305	5.0e-113	400	COG1242	Radical SAM superfamily enzyme	312
649932402	833	33.38	130	827	4	652	1.0e-109	391	COG1199	Rad3-related DNA helicase	654
649932403	245	37.5	3	241	2	222	8.0e-39	154	COG1040	Predicted amidophosphoribosyltransferases	225
649932405	513	60.55	1	510	1	507	0.0e+00	713	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
649932406	154	47.1	1	152	1	154	4.0e-42	163	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
649932407	122	43.86	2	113	1	114	5.0e-28	116	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
649932408	216	40.93	1	214	3	197	2.0e-52	198	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
649932409	418	59.23	3	418	1	417	0.0e+00	578	COG0014	Gamma-glutamyl phosphate reductase	417
649932410	373	57.45	6	373	3	369	2.0e-128	451	COG0263	Glutamate 5-kinase	369
649932411	161	36.03	14	142	36	171	4.0e-22	97.7	COG3216	Uncharacterized conserved protein, DUF2062 family	184
649932412	333	39.82	6	328	2	323	7.0e-61	227	COG0306	Phosphate/sulfate permease	326
649932413	205	29.11	1	204	5	217	1.0e-30	126	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
649932414	231	51.1	5	231	3	224	3.0e-61	228	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
649932418	481	43.86	132	472	3	331	3.0e-94	339	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
649932419	109	64.22	1	109	9	116	7.0e-35	138	COG3169	Uncharacterized conserved protein, DUF486 family	116
649932420	101	29.35	1	92	3	86	1.0e-12	65	COG1359	Quinol monooxygenase YgiN	100
649932421	159	23.68	12	159	7	150	1.0e-19	89.3	COG3305	Uncharacterized membrane protein, DUF2068 family	152
649932422	256	25.99	40	249	42	262	2.0e-19	89.5	COG1082	Sugar phosphate isomerase/epimerase	274
649932423	350	28.38	110	331	3	219	6.0e-27	115	COG0569	Trk K+ transport system, NAD-binding component	225
649932424	230	37.44	6	215	12	221	2.0e-38	152	COG1802	DNA-binding transcriptional regulator, GntR family	230
649932425	462	46.84	70	460	12	395	3.0e-86	312	COG1921	Seryl-tRNA(Sec) selenium transferase	395
649932426	231	42.79	1	228	2	227	3.0e-63	235	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
649932427	158	67.72	1	158	1	158	2.0e-64	237	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
649932428	563	34.55	25	537	1	472	7.0e-107	381	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
649932429	480	57.38	3	480	2	464	0.0e+00	651	COG0215	Cysteinyl-tRNA synthetase	464
649932431	760	23.53	1	347	25	394	6.0e-30	126	COG4624	Iron only hydrogenase large subunit, C-terminal domain	411
649932434	280	45.92	3	234	1	233	1.0e-62	233	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
649932435	252	26.5	15	246	12	240	5.0e-16	78.1	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
649932437	290	42.92	64	275	1	202	8.0e-35	140	COG0310	ABC-type Co2+ transport system, permease component	204
649932438	435	50.69	1	431	2	428	0.0e+00	547	COG0422	Thiamine biosynthesis protein ThiC	432
649932439	463	51.32	2	455	1	451	0.0e+00	534	COG1797	Cobyrinic acid a,c-diamide synthase	451
649932440	197	36.36	2	184	1	187	2.0e-32	131	COG0406	Broad specificity phosphatase PhoE	208
649932441	251	35.89	1	246	2	245	3.0e-30	125	COG0368	Cobalamin synthase	246
649932442	350	42.23	8	347	7	333	2.0e-70	259	COG2038	NaMN:DMB phosphoribosyltransferase	347
649932443	173	47.7	3	173	1	174	5.0e-51	193	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
649932444	211	52.04	4	196	5	200	2.0e-65	242	COG0218	GTP-binding protein EngB required for normal cell division	200
649932445	283	22.73	1	283	9	286	2.0e-33	136	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
649932447	486	30.33	146	471	27	336	3.0e-35	143	COG0642	Signal transduction histidine kinase	336
649932448	455	50	1	455	3	460	0.0e+00	504	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649932449	850	36.24	23	721	6	714	0.0e+00	657	COG0058	Glucan phosphorylase	750
649932450	352	41.6	1	351	2	352	2.0e-97	349	COG1377	Flagellar biosynthesis protein FlhB	363
649932451	261	36.55	13	261	12	258	8.0e-33	134	COG1684	Flagellar biosynthesis protein FliR	258
649932452	89	49.43	1	87	1	87	2.0e-16	77.5	COG1987	Flagellar biosynthesis protein FliQ	89
649932453	252	54.98	1	251	1	247	3.0e-74	271	COG1338	Flagellar biosynthetic protein FliP	248
649932454	155	32.38	31	132	24	128	7.0e-11	60.3	COG3190	Flagellar biogenesis protein FliO	137
649932456	325	30.89	1	325	1	324	2.0e-58	219	COG1868	Flagellar motor switch protein FliM	332
649932457	174	28.57	1	174	1	159	3.0e-21	94.9	COG1580	Flagellar basal body-associated protein FliL	159
649932458	294	30.69	5	294	3	265	5.0e-39	155	COG4786	Flagellar basal body rod protein FlgG	265
649932460	221	39.41	5	207	10	210	7.0e-28	117	COG1843	Flagellar hook assembly protein FlgD	222
649932463	149	28.26	4	141	3	140	1.0e-02	33	COG2882	Flagellar biosynthesis chaperone FliJ	148
649932464	441	54.86	5	435	9	440	0.0e+00	589	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
649932466	330	45.29	2	329	12	339	5.0e-78	284	COG1536	Flagellar motor switch protein FliG	339
649932467	524	35.83	5	521	9	543	3.0e-101	362	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
649932468	101	35.58	1	101	2	105	6.0e-16	75.7	COG1677	Flagellar hook-basal body complex protein FliE	105
649932469	145	52.41	1	145	1	137	1.0e-41	162	COG1558	Flagellar basal body rod protein FlgC	137
649932470	139	33.08	7	137	4	132	2.0e-24	105	COG1815	Flagellar basal body rod protein FlgB	133
649932473	169	28.32	55	166	41	151	2.0e-11	62.2	COG1406	Chemotaxis protein CheX, a CheY~P-specific phosphatase	153
649932475	345	27.51	1	335	105	447	5.0e-42	165	COG5002	Signal transduction histidine kinase	459
649932476	128	45.45	31	126	11	109	5.0e-19	86.5	COG0607	Rhodanese-related sulfurtransferase	110
649932477	276	40.15	4	274	2	258	5.0e-57	214	COG1237	Metal-dependent hydrolase, beta-lactamase superfamily II	259
649932480	1069	27.84	9	1057	1	1007	0.0e+00	648	COG0841	Multidrug efflux pump subunit AcrB	1009
649932481	365	29.07	1	365	4	366	8.0e-18	85.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649932482	447	25.9	26	439	44	443	5.0e-34	139	COG1538	Outer membrane protein TolC	457
649932483	297	48.45	7	296	8	287	1.0e-83	303	COG2607	Predicted ATPase, AAA+ superfamily	287
649932484	272	31	8	258	8	278	5.0e-21	95	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
649932485	164	35.67	10	161	17	173	9.0e-20	90	COG3697	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase)	182
649932486	512	50.93	31	512	31	513	0.0e+00	571	COG3051	Citrate lyase, alpha subunit	513
649932487	306	43.16	9	292	1	280	2.0e-69	256	COG2301	Citrate lyase beta subunit	283
649932488	159	32.39	6	147	3	134	1.0e-17	82.6	COG1661	Predicted DNA-binding protein with PD1-like DNA-binding motif	141
649932489	87	44.32	1	86	1	88	1.0e-17	81.6	COG3052	Citrate lyase, gamma subunit	98
649932490	333	39.24	1	332	4	347	2.0e-75	276	COG3053	Citrate lyase synthetase	352
649932491	237	25.58	1	212	2	210	1.0e-19	90.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649932492	95	56.82	8	95	26	113	4.0e-23	99.6	COG3952	Uncharacterized N-terminal domain of lipid-A-disaccharide synthase	113
649932493	540	24.02	4	448	2	458	3.0e-28	120	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
649932496	135	32.84	3	135	2	135	5.0e-17	80	COG2703	Hemerythrin	144
649932497	181	36.54	2	105	1	104	1.0e-18	86.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
649932501	293	28.16	45	282	21	258	1.0e-32	133	COG2006	Uncharacterized conserved protein, DUF362 family	293
649932502	520	20.72	8	317	13	309	2.0e-14	74.7	COG0348	Polyferredoxin	386
649932503	142	33.08	7	138	6	137	6.0e-24	103	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
649932505	692	35.06	347	633	81	408	1.0e-34	142	COG0840	Methyl-accepting chemotaxis protein	408
649932506	386	41.64	10	386	5	377	3.0e-113	401	COG1454	Alcohol dehydrogenase, class IV	377
649932511	516	22.69	9	368	1	365	1.0e-10	61.7	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
649932513	1732	33.82	156	545	120	498	6.0e-26	114	COG1404	Serine protease, subtilisin family	508
649932517	80	35.37	1	80	1	82	7.0e-12	62.3	COG2336	Antitoxin component of the MazEF toxin-antitoxin module	82
649932518	114	36.04	6	112	1	110	1.0e-19	88.1	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
649932519	200	19.8	1	195	8	198	1.0e-12	66.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649932523	174	29.41	13	165	9	148	5.0e-19	87.4	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
649932526	1963	19.94	339	1961	87	1618	2.0e-85	312	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
649932527	715	33.03	1	707	1	733	1.0e-109	390	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
649932528	134	35.54	15	133	17	136	6.0e-14	70.1	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
649932530	176	41.25	17	176	2	161	1.0e-31	129	COG0700	Spore maturation protein SpmB (function unknown)	162
649932531	191	45.05	1	182	2	183	6.0e-44	170	COG2715	Spore maturation protein SpmA (function unknown)	206
649932532	288	32.44	1	278	10	307	2.0e-53	203	COG1619	Muramoyltetrapeptide carboxypeptidase LdcA (peptidoglycan recycling)	313
649932535	140	31.11	1	130	47	181	1.0e-23	102	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
649932540	448	25.3	115	436	37	348	2.0e-33	137	COG3177	Fic family protein	348
649932541	543	34.58	143	542	10	408	2.0e-48	187	COG0840	Methyl-accepting chemotaxis protein	408
649932542	157	25.83	36	150	8	119	1.0e-09	56.1	COG2346	Truncated hemoglobin YjbI	133
649932547	104	51.61	12	104	6	97	6.0e-23	98.8	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
649932548	93	42.55	1	93	1	94	3.0e-21	93.4	COG3549	Plasmid maintenance system killer protein	94
649932551	166	31	68	166	19	107	1.0e-08	52.6	COG0607	Rhodanese-related sulfurtransferase	110
649932552	334	20.61	1	130	1	127	7.0e-10	58.3	COG1943	REP element-mobilizing transposase RayT	136
649932557	660	23.63	8	656	11	587	2.0e-40	161	COG4715	Uncharacterized conserved protein, contains Zn finger domain	587
649932560	95	50	16	93	20	97	8.0e-20	88.7	COG1669	Predicted nucleotidyltransferase	97
649932568	336	31.4	80	246	4	205	2.0e-25	110	COG3179	Predicted chitinase	206
649932569	484	48.52	10	483	4	472	3.0e-107	382	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
649932570	545	53.39	4	505	3	497	0.0e+00	530	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
649932571	667	42.66	5	663	1	606	0.0e+00	492	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
649932572	100	55.56	1	99	1	99	5.0e-23	99.4	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
649932573	167	36.75	1	166	3	165	4.0e-16	78	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
649932574	132	45.8	3	132	13	139	2.0e-35	141	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
649932575	349	50.72	5	346	3	329	8.0e-100	357	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
649932576	821	31.37	1	808	5	915	0.0e+00	617	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
649932577	593	53.96	108	524	4	420	0.0e+00	601	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
649932578	168	44.3	16	164	10	158	5.0e-43	167	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
649932579	389	59.33	4	389	13	398	0.0e+00	570	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
649932580	161	43.95	1	157	3	158	6.0e-39	153	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
649932581	170	57.74	2	168	12	179	2.0e-68	251	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
649932582	118	54.24	1	118	4	121	3.0e-29	120	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
649932583	427	62.15	1	427	2	429	0.0e+00	623	COG0001	Glutamate-1-semialdehyde aminotransferase	432
649932587	229	37.74	28	227	34	245	5.0e-37	148	COG0356	FoF1-type ATP synthase, membrane subunit a	246
649932588	91	49.32	5	77	7	79	2.0e-07	47.1	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
649932589	286	30.67	54	286	4	237	1.0e-37	150	COG1387	Histidinol phosphatase or related hydrolase of the PHP family	237
649932590	308	29.5	49	308	38	290	3.0e-09	56.4	COG5006	Threonine/homoserine efflux transporter RhtA	292
649932591	526	64.05	5	525	6	528	0.0e+00	822	COG4108	Peptide chain release factor RF-3	528
649932593	262	45.31	1	252	2	256	2.0e-72	265	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
649932594	165	26.17	3	150	21	169	7.0e-12	63.5	COG1633	Rubrerythrin	176
649932597	468	49.56	1	456	2	453	0.0e+00	497	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649932598	165	44.22	14	160	14	159	2.0e-35	141	COG0835	Chemotaxis signal transduction protein	165
649932599	614	43.7	91	614	196	711	0.0e+00	492	COG0643	Chemotaxis protein histidine kinase CheA	716
649932600	290	36.5	18	290	1	265	6.0e-64	237	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
649932601	303	26.16	10	242	13	247	5.0e-33	135	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
649932602	356	43.1	8	355	1	342	2.0e-87	316	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
649932604	343	22.67	166	334	42	207	8.0e-04	38.4	COG3577	Predicted aspartyl protease	215
649932605	462	34.23	13	455	15	455	5.0e-63	235	COG0534	Na+-driven multidrug efflux pump	455
649932606	138	43.8	1	135	1	135	2.0e-24	105	COG0355	FoF1-type ATP synthase, epsilon subunit	135
649932607	470	78.25	4	469	2	466	0.0e+00	811	COG0055	FoF1-type ATP synthase, beta subunit	468
649932608	287	45.99	5	286	1	287	6.0e-82	297	COG0224	FoF1-type ATP synthase, gamma subunit	287
649932609	502	68.33	1	502	1	502	0.0e+00	812	COG0056	FoF1-type ATP synthase, alpha subunit	504
649932610	180	35.39	1	178	2	178	1.0e-35	143	COG0712	FoF1-type ATP synthase, delta subunit	178
649932611	204	34.21	49	200	8	158	1.0e-08	53	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
649932612	141	31.91	1	141	2	142	4.0e-07	47.2	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
649932613	279	41.06	29	273	8	240	4.0e-30	125	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
649932614	257	45.28	1	252	1	253	3.0e-60	225	COG1192	Cellulose biosynthesis protein BcsQ	259
649932618	614	44.24	7	604	9	581	0.0e+00	554	COG0322	Excinuclease UvrABC, nuclease subunit	581
649932619	195	27.13	7	190	5	180	5.0e-15	74.6	COG2229	Signal recognition particle receptor subunit beta, a GTPase	187
649932620	163	25.64	15	130	4	119	3.0e-06	44.8	COG2018	Predicted regulator of Ras-like GTPase activity, Roadblock/LC7/MglB family	119
649932621	469	33.91	1	461	6	451	4.0e-93	335	COG1109	Phosphomannomutase	464
649932622	193	48.78	29	190	2	155	8.0e-48	183	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
649932624	238	27.03	8	238	21	279	6.0e-07	48.1	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
649932625	168	46.39	1	165	1	162	4.0e-45	174	COG0242	Peptide deformylase	168
649932626	188	26.74	12	180	6	172	4.0e-14	71.4	COG2716	Glycine cleavage system regulatory protein	176
649932628	558	50.18	7	556	5	555	0.0e+00	608	COG0595	mRNA degradation ribonuclease J1/J2	555
649932631	231	38.86	6	230	4	226	5.0e-34	137	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
649932632	150	41.32	2	150	1	167	4.0e-34	137	COG0629	Single-stranded DNA-binding protein	167
649932633	198	19.55	1	179	8	179	5.0e-11	61.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649932634	384	26.4	14	379	3	372	1.0e-22	100	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649932635	1036	27.61	5	1012	1	1008	0.0e+00	784	COG0841	Multidrug efflux pump subunit AcrB	1009
649932636	469	40.61	13	469	2	447	3.0e-69	256	COG1538	Outer membrane protein TolC	457
649932640	446	35.87	1	440	2	444	5.0e-62	232	COG0534	Na+-driven multidrug efflux pump	455
649932641	356	20.64	111	309	31	239	4.0e-03	36	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
649932642	326	50.15	1	325	1	321	9.0e-101	360	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
649932646	453	57.4	5	453	3	453	0.0e+00	572	COG1066	Predicted ATP-dependent serine protease	456
649932647	118	52.54	1	118	1	118	2.0e-23	101	COG1734	RNA polymerase-binding transcription factor DksA	120
649932652	273	31.5	129	250	22	141	3.0e-10	59.3	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
649932653	219	41.75	29	218	4	191	2.0e-37	148	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
649932654	167	42.33	3	163	2	161	5.0e-35	140	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
649932655	116	43.93	8	114	1	107	5.0e-23	99.6	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
649932656	407	48.12	1	395	6	403	9.0e-110	390	COG0303	Molybdopterin biosynthesis enzyme	404
649932657	245	27.49	1	244	2	252	3.0e-08	52.3	COG0730	Uncharacterized membrane protein YfcA	258
649932658	951	33.73	179	514	11	336	4.0e-49	190	COG0642	Signal transduction histidine kinase	336
649932661	167	59.12	1	156	1	158	3.0e-59	220	COG2077	Peroxiredoxin	158
649932662	334	22.94	9	332	20	341	8.0e-10	58.4	COG0628	Predicted PurR-regulated permease PerM	355
649932663	437	22.99	54	139	1	79	1.0e-03	38.4	COG0695	Glutaredoxin	80
649932664	593	25.17	174	452	58	329	4.0e-30	126	COG0642	Signal transduction histidine kinase	336
649932667	275	25.49	159	249	14	109	5.0e-05	41.9	COG3474	Cytochrome c2	135
649932677	441	25.57	51	353	12	277	4.0e-32	132	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
649932678	307	27.63	1	301	1	296	6.0e-32	131	COG0583	DNA-binding transcriptional regulator, LysR family	297
649932679	207	21.65	14	207	7	198	5.0e-09	54.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649932680	419	33.17	24	417	43	443	2.0e-34	140	COG1538	Outer membrane protein TolC	457
649932681	390	23.39	1	275	4	286	4.0e-23	102	COG1566	Multidrug resistance efflux pump	352
649932682	400	18.57	12	400	1	418	9.0e-11	61.7	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649932683	227	45.5	4	224	2	220	5.0e-69	254	COG1136	ABC-type lipoprotein export system, ATPase component	226
649932684	131	32.79	1	118	1	121	1.0e-15	75.7	COG1433	Predicted Fe-Mo cluster-binding protein, NifX family	121
649932685	120	50	1	94	1	91	7.0e-21	92.7	COG1342	Predicted DNA-binding protein, UPF0251 family	99
649932688	430	37.28	44	429	1	379	1.0e-83	304	COG1775	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB	379
649932690	141	22.45	33	130	12	99	3.0e-05	41.1	COG0607	Rhodanese-related sulfurtransferase	110
649932691	395	22.17	6	393	2	378	2.0e-32	133	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
649932696	472	21.04	106	439	18	345	4.0e-32	133	COG0641	Sulfatase maturation enzyme AslB, radical SAM superfamily	378
649932697	222	45.02	12	219	15	225	3.0e-46	178	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
649932698	366	19.3	1	365	1	352	8.0e-24	104	COG0857	BioD-like N-terminal domain of phosphotransacetylase	354
649932701	169	45.05	1	167	3	184	2.0e-30	125	COG0693	Putative intracellular protease/amidase	188
649932702	410	30.6	9	410	4	390	1.0e-67	250	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
649932703	267	53.01	1	266	2	266	2.0e-88	319	COG0289	Dihydrodipicolinate reductase	266
649932704	290	55.02	1	286	4	292	2.0e-95	342	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
649932705	417	46.72	1	390	1	394	9.0e-117	413	COG0019	Diaminopimelate decarboxylase	394
649932706	217	37.56	6	217	2	213	5.0e-43	167	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
649932707	624	61.74	4	624	1	620	0.0e+00	919	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
649932709	455	48.37	1	455	1	454	0.0e+00	500	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
649932710	537	44.33	253	533	7	295	6.0e-66	245	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
649932711	117	39.09	6	113	1	110	2.0e-15	74.5	COG0594	RNase P protein component	117
649932712	49	81.82	1	44	1	44	5.0e-04	36	COG0230	Ribosomal protein L34	44
650641554	97	52.63	1	95	16	110	1.0e-30	124	COG4226	Predicted nuclease of the RNAse H fold, HicB family	111
650641556	62	33.33	1	48	7	54	5.0e-06	43	COG1724	Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family	66
650641557	441	33.01	11	397	15	422	9.0e-51	194	COG0038	H+/Cl- antiporter ClcA	443
650641585	822	46.75	383	536	1	153	5.0e-35	143	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
650641598	326	23.38	1	313	85	402	1.0e-30	127	COG3464	Transposase	402
650641616	92	42.55	1	92	1	94	4.0e-21	92.6	COG3549	Plasmid maintenance system killer protein	94
650641617	532	26.16	7	394	1	391	2.0e-41	163	COG0183	Acetyl-CoA acetyltransferase	392
650641642	66	69.23	1	65	9	73	6.0e-24	102	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
