gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
647044105	463	22.73	86	406	9	273	3.0e-07	50.6	COG4974	Site-specific recombinase XerD	300
647044106	266	47.83	1	251	3	254	1.0e-49	190	COG1484	DNA replication protein DnaC	254
647044113	788	37.09	1	572	1	562	0.0e+00	465	COG0550	DNA topoisomerase IA	570
647044116	85	31.76	1	85	19	102	6.0e-13	65.7	COG3702	Type IV secretory pathway, VirB3 components	105
647044117	830	38.33	1	822	1	794	0.0e+00	673	COG3451	Type IV secretory pathway, VirB4 component	796
647044121	365	21.47	6	307	42	363	2.0e-18	86.6	COG3704	Type IV secretory pathway, VirB6 components	406
647044123	253	41.52	25	246	12	232	3.0e-52	198	COG3736	Type IV secretory pathway, component VirB8	239
647044124	292	31.14	2	289	8	263	1.0e-43	170	COG3504	Type IV secretory pathway, VirB9 components	265
647044125	368	31.52	23	366	24	358	9.0e-58	217	COG2948	Type IV secretory pathway, VirB10 components	360
647044126	327	31.43	1	314	22	309	4.0e-58	218	COG0630	Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase	312
647044135	286	23.62	1	254	2	230	4.0e-23	101	COG1192	Cellulose biosynthesis protein BcsQ	259
647044137	121	22.76	5	120	7	128	2.0e-08	51.2	COG0629	Single-stranded DNA-binding protein	167
647044142	208	30.92	1	207	3	251	5.0e-25	107	COG1192	Cellulose biosynthesis protein BcsQ	259
647044147	711	26.5	22	711	1	619	2.0e-101	363	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
647044158	183	24.82	40	179	3	138	2.0e-08	52.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
647044160	1083	35.51	46	1076	2	1067	0.0e+00	913	COG0587	DNA polymerase III, alpha subunit	1139
647044162	472	18.84	10	338	5	347	1.0e-05	44.9	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
647044164	201	41.87	1	200	1	199	4.0e-40	157	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
647044166	141	41.6	1	124	2	125	5.0e-22	96.9	COG3654	Prophage maintenance system killer protein	132
647044170	516	43.48	76	466	2	369	1.0e-125	443	COG1415	Uncharacterized protein	373
647044171	192	56.76	24	170	3	150	5.0e-54	203	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
647044172	354	36.34	1	339	1	282	8.0e-59	221	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
647044176	830	37.51	1	829	110	933	0.0e+00	871	COG0178	Excinuclease UvrABC ATPase subunit	935
647044178	248	32.6	20	236	17	239	5.0e-42	164	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
647044180	569	33.85	228	551	2	304	6.0e-57	215	COG0492	Thioredoxin reductase	305
647044181	209	27.78	1	185	2	194	8.0e-16	77.4	COG3145	Alkylated DNA repair dioxygenase AlkB	194
647044183	326	29.46	1	256	1	255	3.0e-39	155	COG0300	Short-chain dehydrogenase	265
647044184	763	37.74	2	763	22	755	0.0e+00	553	COG3537	Putative alpha-1,2-mannosidase	768
647044185	283	19.67	41	271	4	225	1.0e-08	53.8	COG2801	Transposase InsO and inactivated derivatives	232
647044191	269	38.52	3	256	1	248	1.0e-42	166	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647044192	266	39.77	4	264	3	251	4.0e-42	165	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647044195	310	32.79	187	307	2	119	5.0e-14	72.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647044205	371	29.51	3	347	16	359	7.0e-64	238	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
647044206	411	49.51	2	411	26	426	2.0e-127	449	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
647044207	346	24.32	47	304	48	295	5.0e-19	89	COG3239	Fatty acid desaturase	343
647044208	293	32.33	16	277	2	243	3.0e-42	165	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
647044209	194	31.5	1	193	6	205	3.0e-16	78.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
647044210	289	47.21	1	269	23	291	1.0e-98	352	COG1897	Homoserine trans-succinylase	307
647044211	450	34.35	1	449	1	443	2.0e-111	396	COG0174	Glutamine synthetase	443
647044229	349	27.83	7	342	3	334	2.0e-51	196	COG0859	ADP-heptose:LPS heptosyltransferase	334
647044232	343	41.92	13	343	1	322	2.0e-88	319	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
647044233	165	46.1	7	160	1	152	1.0e-45	175	COG0315	Molybdenum cofactor biosynthesis enzyme	157
647044234	81	33.33	4	81	1	84	2.0e-09	54.6	COG1977	Molybdopterin converting factor, small subunit	84
647044235	149	42.54	11	143	6	138	7.0e-33	133	COG0314	Molybdopterin synthase catalytic subunit	149
647044242	176	50.78	48	175	10	137	1.0e-37	149	COG3011	Predicted thiol-disulfide oxidoreductase YuxK, DCC family	137
647044243	812	44.17	1	804	2	773	0.0e+00	676	COG4993	Glucose dehydrogenase	773
647044244	455	41.72	1	452	14	477	0.0e+00	462	COG0380	Trehalose-6-phosphate synthase	486
647044245	592	29.45	7	585	18	605	7.0e-73	268	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
647044246	252	33.6	1	247	2	250	1.0e-40	160	COG1877	Trehalose-6-phosphatase	266
647044248	811	20.61	1	811	3	699	5.0e-37	150	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
647044251	537	21.67	19	380	1	360	1.0e-07	51.7	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
647044255	102	35.71	3	86	1	84	1.0e-17	81.1	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
647044257	601	21.57	3	601	151	768	4.0e-31	130	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647044258	442	28.5	37	419	17	336	6.0e-43	168	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
647044259	346	42.32	13	328	1	306	2.0e-74	273	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
647044260	372	27.88	53	372	5	334	4.0e-37	148	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
647044261	326	51.75	63	319	2	258	2.0e-65	242	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
647044262	275	47.08	10	241	4	243	2.0e-73	268	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
647044264	861	57.46	5	860	1	783	0.0e+00	987	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
647044272	756	32.07	54	627	9	561	3.0e-113	403	COG3533	Uncharacterized conserved protein, DUF1680 family	589
647044290	546	16.23	29	545	53	608	1.0e-24	108	COG1874	Beta-galactosidase GanA	673
647044291	779	23.75	190	765	56	619	2.0e-35	144	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
647044292	528	29.95	9	447	8	442	8.0e-37	148	COG0531	Amino acid transporter	466
647044293	610	43.2	12	585	3	587	0.0e+00	571	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
647044294	610	43.38	38	601	18	588	0.0e+00	566	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
647044295	399	36.84	24	390	2	376	2.0e-78	286	COG0006	Xaa-Pro aminopeptidase	384
647044296	538	27.66	16	501	4	465	4.0e-45	176	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647044297	302	37.89	7	289	5	288	1.0e-64	240	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
647044298	437	21.01	10	402	1	393	5.0e-19	89.2	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
647044300	425	27.88	56	423	2	385	2.0e-34	140	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647044301	312	37.27	1	311	4	333	8.0e-76	277	COG3938	Proline racemase	341
647044302	238	31.67	120	238	6	125	1.0e-20	93.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647044303	551	52.12	229	546	11	340	3.0e-108	385	COG0552	Signal recognition particle GTPase	340
647044305	357	48.31	5	357	3	340	6.0e-103	367	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
647044306	92	57.95	1	88	1	88	1.0e-33	134	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
647044318	597	30.23	35	457	6	387	1.0e-62	234	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647044319	209	25	39	190	1	145	3.0e-14	71.9	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
647044321	638	57.35	7	625	2	625	0.0e+00	891	COG1154	Deoxyxylulose-5-phosphate synthase	627
647044322	418	24.07	1	416	2	405	2.0e-35	143	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
647044324	384	19.24	3	328	13	349	2.0e-10	60.3	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
647044325	319	25.67	4	313	2	307	9.0e-31	127	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647044327	282	19.83	37	269	27	210	7.0e-07	47.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647044328	343	36.5	18	343	5	322	3.0e-64	239	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
647044330	153	43.15	3	146	4	149	3.0e-30	124	COG3542	Predicted sugar epimerase, cupin superfamily	162
647044332	228	34.29	23	228	9	217	8.0e-47	180	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
647044334	398	15.79	72	371	38	372	2.0e-06	47.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647044335	496	26.5	11	483	1	478	1.0e-26	114	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
647044336	349	20.95	58	343	81	380	1.0e-08	54.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647044337	380	24.28	1	371	1	379	6.0e-32	132	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647044338	358	27.03	22	354	3	325	2.0e-23	103	COG3594	Fucose 4-O-acetylase or related acetyltransferase	343
647044339	363	22.81	27	358	4	326	4.0e-27	116	COG3594	Fucose 4-O-acetylase or related acetyltransferase	343
647044341	484	42.74	251	484	1	226	6.0e-68	252	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
647044342	474	29.62	22	465	11	453	2.0e-63	237	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
647044343	202	33.01	1	202	27	228	2.0e-29	122	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
647044346	118	27.45	19	118	1	101	2.0e-11	60.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
647044347	99	45.16	2	94	1	93	8.0e-29	118	COG0776	Bacterial nucleoid DNA-binding protein	94
647044348	792	41.68	142	791	1	650	0.0e+00	622	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
647044349	331	53.57	1	329	3	335	4.0e-124	438	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
647044351	112	71.82	2	111	9	118	3.0e-35	139	COG0292	Ribosomal protein L20	118
647044352	65	55.38	1	65	1	65	1.0e-10	58.3	COG0291	Ribosomal protein L35	65
647044353	159	63.92	1	158	18	175	2.0e-56	211	COG0290	Translation initiation factor IF-3	176
647044354	636	52.92	36	633	1	579	0.0e+00	773	COG0441	Threonyl-tRNA synthetase	589
647044355	253	27.57	2	244	4	221	3.0e-22	99.1	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
647044356	375	34.04	1	373	1	326	2.0e-52	199	COG0306	Phosphate/sulfate permease	326
647044357	208	22.44	12	207	13	217	1.0e-08	53.3	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
647044359	446	39.15	1	443	4	429	1.0e-103	370	COG1253	Hemolysin or related protein, contains CBS domains	429
647044360	222	34.27	28	202	14	189	6.0e-23	101	COG3932	Uncharacterized conserved protein	209
647044361	166	39.84	6	133	3	130	3.0e-33	135	COG3871	General stress protein 26 (function unknown)	145
647044362	333	26.61	15	324	8	331	3.0e-37	149	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
647044364	576	23.36	26	554	4	536	4.0e-43	169	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647044367	517	23.97	41	456	24	443	4.0e-28	119	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
647044369	364	29.89	1	364	1	378	2.0e-26	113	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647044370	351	21.65	32	344	53	379	1.0e-21	97.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647044372	415	21.92	20	315	17	372	4.0e-19	89.8	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
647044377	417	25.78	1	413	6	413	1.0e-09	58.2	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
647044378	370	41.49	3	366	1	370	8.0e-94	337	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
647044383	261	40.7	91	260	10	181	3.0e-31	129	COG3038	Cytochrome b561	181
647044385	130	40.98	12	130	13	131	7.0e-20	89.6	COG3474	Cytochrome c2	135
647044387	193	30.77	11	186	1	182	2.0e-23	102	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
647044390	252	40.17	7	244	36	274	3.0e-35	142	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
647044391	68	36.73	2	50	7	55	7.0e-07	45.7	COG3114	Heme exporter protein D	67
647044392	156	52.11	1	141	1	142	8.0e-44	169	COG2332	Cytochrome c-type biogenesis protein CcmE	153
647044393	662	53.25	1	638	1	642	0.0e+00	599	COG1138	Cytochrome c biogenesis factor	648
647044394	180	25.98	32	155	3	127	2.0e-09	55.7	COG0526	Thiol-disulfide isomerase or thioredoxin	127
647044395	161	45.07	20	160	3	144	7.0e-38	149	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
647044398	505	33.72	10	265	3	260	2.0e-41	164	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
647044405	703	31.44	320	698	11	408	4.0e-42	167	COG0840	Methyl-accepting chemotaxis protein	408
647044412	271	49.63	1	133	5	137	9.0e-46	177	COG2904	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, N-terminal domain	137
647044413	438	45.19	31	432	5	389	3.0e-103	369	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
647044414	412	30.92	34	375	25	365	5.0e-34	139	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
647044415	1082	35.92	2	1053	1	1008	0.0e+00	871	COG0841	Multidrug efflux pump subunit AcrB	1009
647044416	1042	35.78	2	1017	1	1009	0.0e+00	845	COG0841	Multidrug efflux pump subunit AcrB	1009
647044418	109	46.6	1	103	24	126	9.0e-29	118	COG3607	Predicted lactoylglutathione lyase	133
647044419	455	31.35	3	255	1	290	2.0e-49	190	COG5383	Uncharacterized metalloenzyme YdcJ, glyoxalase superfamily	295
647044424	249	20.18	10	232	2	225	3.0e-17	82.3	COG1011	FMN phosphatase YigB, HAD superfamily	229
647044429	248	32.29	25	246	8	211	7.0e-35	140	COG2173	D-alanyl-D-alanine dipeptidase	211
647044430	286	37.2	40	265	7	254	1.0e-41	163	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
647044433	365	33.33	1	358	1	360	2.0e-61	229	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
647044435	258	28.26	8	227	3	209	3.0e-19	88.9	COG3786	L,D-peptidoglycan transpeptidase YkuD, ErfK/YbiS/YcfS/YnhG family	217
647044436	438	32.79	21	430	19	444	4.0e-33	136	COG0531	Amino acid transporter	466
647044439	144	53.66	4	126	6	128	1.0e-34	138	COG4682	Uncharacterized membrane protein YiaA	128
647044440	392	35.57	1	382	8	396	6.0e-68	251	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
647044442	723	38.66	13	432	1	391	2.0e-80	294	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
647044443	118	48.31	1	117	2	119	1.0e-30	125	COG1539	Dihydroneopterin aldolase	121
647044444	576	47.07	66	576	1	500	0.0e+00	562	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
647044447	529	27.66	14	484	52	513	1.0e-56	214	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
647044448	141	36.43	1	123	1	125	2.0e-13	68.5	COG4969	Tfp pilus assembly protein, major pilin PilA	125
647044450	341	43.4	1	341	58	397	1.0e-98	353	COG1459	Type II secretory pathway, component PulF	397
647044451	287	43.46	18	276	10	245	8.0e-38	150	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
647044452	201	47.42	5	197	4	194	4.0e-48	184	COG0237	Dephospho-CoA kinase	201
647044453	444	27.85	138	442	19	327	2.0e-36	147	COG0642	Signal transduction histidine kinase	336
647044454	225	40	1	224	1	229	3.0e-52	198	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647044456	305	36.48	11	302	1	317	2.0e-59	223	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
647044457	710	51.54	11	709	8	694	0.0e+00	808	COG1523	Pullulanase/glycogen debranching enzyme	697
647044458	130	22.13	10	125	12	128	4.0e-11	60.4	COG2916	DNA-binding protein H-NS	128
647044460	277	31.33	64	204	33	180	3.0e-22	99.2	COG1525	Endonuclease YncB, thermonuclease family	192
647044467	270	41.06	1	261	1	256	2.0e-68	252	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
647044468	305	28.23	9	300	7	295	1.0e-25	110	COG0583	DNA-binding transcriptional regulator, LysR family	297
647044469	350	25.52	24	340	26	353	1.0e-29	124	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
647044470	319	32.33	3	258	5	266	2.0e-45	176	COG1018	Ferredoxin-NADP reductase	266
647044472	437	56.71	6	436	10	434	6.0e-118	418	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
647044475	357	36.53	10	354	103	475	2.0e-69	256	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
647044479	414	18.86	1	380	12	394	4.0e-08	52.9	COG2814	Predicted arabinose efflux permease, MFS family	394
647044481	97	39.73	1	73	8	79	5.0e-14	69.3	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
647044484	588	59.56	1	586	1	585	0.0e+00	878	COG0173	Aspartyl-tRNA synthetase	585
647044486	175	19.35	1	151	11	154	3.0e-09	55	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
647044489	242	55.32	3	236	6	238	2.0e-87	315	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
647044490	174	49.07	5	165	1	160	3.0e-47	181	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
647044491	194	44.28	1	193	1	201	5.0e-54	203	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
647044492	635	58.36	14	635	10	627	0.0e+00	839	COG3158	K+ transporter	627
647044494	345	67.47	2	333	1	332	0.0e+00	532	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
647044495	152	37.4	16	146	6	135	9.0e-31	126	COG0824	Acyl-CoA thioesterase FadM	137
647044496	259	44.65	42	256	1	214	3.0e-47	182	COG0811	Biopolymer transport protein ExbB/TolQ	216
647044501	439	46.34	27	435	18	424	6.0e-105	374	COG0823	Periplasmic component of the Tol biopolymer transport system	425
647044502	172	30.11	12	172	15	190	4.0e-32	130	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
647044503	272	32.22	2	266	4	262	3.0e-39	155	COG1729	Periplasmic TolA-binding protein (function unknown)	262
647044504	227	33.33	16	223	2	212	3.0e-40	158	COG0602	Organic radical activating enzyme	212
647044513	234	25.95	1	233	15	264	4.0e-30	125	COG0863	DNA modification methylase	302
647044515	340	29.87	20	335	38	432	9.0e-69	254	COG5518	Bacteriophage capsid portal protein	492
647044517	323	26.48	18	304	7	275	2.0e-44	173	COG5484	Uncharacterized protein YjcR	279
647044522	69	50.72	1	69	3	70	2.0e-14	70.8	COG5004	P2-like prophage tail protein X	70
647044525	212	39.52	1	209	3	204	3.0e-34	138	COG3179	Predicted chitinase	206
647044531	296	50.99	2	296	3	306	3.0e-80	291	COG3948	Phage-related baseplate assembly protein	306
647044532	181	44.94	1	155	2	159	5.0e-40	157	COG4385	Bacteriophage P2-related tail formation protein	206
647044533	501	25.52	251	380	6	148	1.0e-09	58.4	COG4675	Microcystin-dependent protein  (function unknown)	170
647044535	187	42.31	8	186	2	183	2.0e-28	118	COG4540	Phage P2 baseplate assembly protein gpV	184
647044536	119	44.34	1	106	5	109	2.0e-20	91.6	COG3628	Phage baseplate assembly protein W	116
647044537	388	49.49	1	386	1	394	3.0e-102	365	COG3497	Phage tail sheath protein FI	394
647044538	169	50.89	1	168	1	168	1.0e-52	199	COG3498	Phage tail tube protein FII	169
647044544	133	56	1	125	1	125	6.0e-37	146	COG3499	Phage protein U	147
647044545	327	41.25	3	323	4	338	2.0e-68	253	COG3500	Phage protein D	350
647044567	394	23.26	90	382	20	283	2.0e-06	47.1	COG4974	Site-specific recombinase XerD	300
647044569	224	51.79	1	220	2	219	3.0e-71	261	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
647044570	364	34.58	149	356	5	216	2.0e-43	169	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
647044575	236	29.51	3	236	1	239	2.0e-34	138	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
647044582	598	50.84	1	596	1	586	0.0e+00	736	COG0514	Superfamily II DNA helicase RecQ	590
647044583	182	46.2	25	182	2	156	9.0e-49	186	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
647044584	1373	41.89	51	682	23	652	0.0e+00	576	COG1643	HrpA-like RNA helicase	845
647044585	878	17.97	271	878	174	768	1.0e-21	98.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647044586	344	38.44	22	339	8	320	2.0e-66	245	COG0837	Glucokinase	320
647044587	504	49.38	14	496	27	505	0.0e+00	540	COG4287	PhoPQ-activated pathogenicity-related protein	507
647044590	372	27.65	6	337	17	346	4.0e-40	159	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
647044592	250	38.16	9	235	10	236	4.0e-42	164	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
647044593	299	25.09	1	271	4	240	1.0e-18	87.1	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
647044595	719	48.87	56	718	60	701	0.0e+00	745	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
647044599	698	29.8	70	317	3	255	9.0e-38	152	COG1216	Glycosyltransferase, GT2 family	305
647044600	814	35.89	101	787	2	661	0.0e+00	476	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
647044602	674	36.73	12	640	1	637	0.0e+00	464	COG1199	Rad3-related DNA helicase	654
647044603	239	39.82	1	222	1	218	6.0e-38	151	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
647044604	304	30.91	4	299	2	314	2.0e-43	169	COG1397	ADP-ribosylglycohydrolase	314
647044605	291	24.44	15	284	1	244	2.0e-15	76.3	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
647044606	316	41.93	3	312	1	313	3.0e-71	262	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
647044610	176	28.57	23	176	9	162	3.0e-25	108	COG0835	Chemotaxis signal transduction protein	165
647044611	678	35.03	344	676	78	408	9.0e-41	162	COG0840	Methyl-accepting chemotaxis protein	408
647044612	2280	32.2	1510	2136	3	709	5.0e-121	430	COG0643	Chemotaxis protein histidine kinase CheA	716
647044613	395	17.69	5	395	4	344	1.0e-17	84.6	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
647044614	158	18.18	5	145	14	151	9.0e-07	46.4	COG0835	Chemotaxis signal transduction protein	165
647044615	197	31.1	24	184	19	181	3.0e-20	91.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
647044621	197	29.41	9	191	8	191	5.0e-14	71.2	COG3230	Heme oxygenase	196
647044622	421	25.06	6	410	3	393	6.0e-20	92.2	COG2814	Predicted arabinose efflux permease, MFS family	394
647044624	713	45.17	2	321	25	341	2.0e-80	294	COG2951	Membrane-bound lytic murein transglycosylase B	343
647044629	201	24.38	1	199	55	255	3.0e-07	48.9	COG0730	Uncharacterized membrane protein YfcA	258
647044630	1338	26.35	1	1103	1	1083	0.0e+00	550	COG4913	Uncharacterized protein YPO0396	1104
647044634	200	52.85	3	194	2	192	4.0e-70	257	COG0302	GTP cyclohydrolase I	195
647044635	150	30.77	18	134	2	118	4.0e-09	54.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
647044637	307	34.6	12	301	18	352	1.0e-49	190	COG1566	Multidrug resistance efflux pump	352
647044638	482	33.56	35	481	8	454	2.0e-44	174	COG1538	Outer membrane protein TolC	457
647044642	421	33.33	13	418	10	435	2.0e-63	237	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
647044650	349	29.24	81	347	16	289	1.0e-39	157	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
647044657	163	70.27	16	163	7	154	8.0e-61	226	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
647044665	96	51.04	1	96	2	96	2.0e-22	96.9	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
647044666	93	46.24	1	92	1	93	3.0e-23	99	COG3549	Plasmid maintenance system killer protein	94
647044667	1120	28.47	177	980	3	760	9.0e-121	428	COG3537	Putative alpha-1,2-mannosidase	768
647044668	65	42.86	10	65	11	62	5.0e-11	59.6	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
647044669	370	23.25	3	370	2	379	4.0e-18	86.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647044670	430	24.82	8	421	21	409	1.0e-15	77.9	COG3307	O-antigen ligase	424
647044672	306	42.05	10	306	7	308	8.0e-83	300	COG1560	Lauroyl/myristoyl acyltransferase	308
647044673	438	49.64	10	428	1	419	0.0e+00	492	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
647044674	460	32.88	8	442	29	454	1.0e-42	167	COG1538	Outer membrane protein TolC	457
647044675	218	38.73	8	209	1	203	2.0e-53	202	COG2518	Protein-L-isoaspartate O-methyltransferase	209
647044676	217	24.48	24	215	13	201	3.0e-11	62.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647044677	975	25	35	645	35	651	3.0e-48	187	COG3292	Periplasmic ligand-binding sensor domain	671
647044679	294	35.45	1	293	1	295	1.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
647044680	479	55.58	2	472	1	422	0.0e+00	614	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
647044681	215	58.77	1	211	1	190	2.0e-79	288	COG0066	3-isopropylmalate dehydratase small subunit	191
647044683	357	55.52	1	357	2	345	5.0e-127	447	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
647044685	520	47.94	11	417	2	409	2.0e-118	419	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
647044686	374	44.68	20	329	6	334	1.0e-85	310	COG1171	Threonine dehydratase	347
647044687	85	45	1	80	2	80	6.0e-20	88.9	COG3978	Acetolactate synthase small subunit, contains ACT domain	86
647044688	573	51.82	10	555	2	549	0.0e+00	616	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
647044689	333	63.34	8	318	20	330	0.0e+00	489	COG0059	Ketol-acid reductoisomerase	338
647044691	625	66.52	136	593	1	432	0.0e+00	756	COG0422	Thiamine biosynthesis protein ThiC	432
647044695	402	29.83	160	375	12	247	2.0e-20	93.9	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
647044696	178	54.6	1	174	1	170	2.0e-55	208	COG0221	Inorganic pyrophosphatase	171
647044699	675	61.67	7	675	6	699	0.0e+00	782	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
647044701	418	25.26	5	384	4	347	2.0e-54	207	COG0205	6-phosphofructokinase	347
647044703	187	48.39	1	186	1	178	3.0e-50	191	COG0563	Adenylate kinase or related kinase	178
647044705	452	45.36	1	452	7	458	0.0e+00	470	COG0773	UDP-N-acetylmuramate-alanine ligase	459
647044706	194	29.21	1	193	4	204	5.0e-24	104	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
647044707	294	36.43	12	288	20	299	8.0e-52	197	COG3781	Predicted membrane chloride channel, bestrophin family	306
647044708	690	32.98	15	198	12	199	1.0e-28	122	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
647044710	271	31.62	1	251	1	243	4.0e-25	108	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647044712	290	16.27	77	280	14	210	3.0e-06	45.9	COG1226	Voltage-gated potassium channel Kch	212
647044713	408	52.54	13	406	15	401	0.0e+00	503	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
647044714	196	24.87	2	177	9	195	1.0e-10	59.9	COG1011	FMN phosphatase YigB, HAD superfamily	229
647044715	760	15.78	1	760	10	768	4.0e-29	123	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647044716	527	38.17	44	518	5	445	3.0e-99	356	COG1231	Monoamine oxidase	450
647044720	385	32.63	37	360	27	354	7.0e-59	221	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
647044721	149	48.67	1	149	1	150	4.0e-49	186	COG3241	Azurin	151
647044722	923	28.46	24	911	7	894	6.0e-87	316	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
647044724	429	60.7	1	429	2	431	0.0e+00	596	COG0001	Glutamate-1-semialdehyde aminotransferase	432
647044727	207	43	8	203	6	204	2.0e-40	158	COG0352	Thiamine monophosphate synthase	211
647044728	63	51.85	9	62	1	54	6.0e-14	69.1	COG1773	Rubredoxin	55
647044729	278	36.9	8	278	3	269	6.0e-59	221	COG2912	Regulator of sirC expression, contains transglutaminase-like and TPR domains	269
647044730	208	36.29	84	207	8	126	5.0e-30	124	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
647044731	204	57.55	1	204	3	213	2.0e-75	275	COG0120	Ribose 5-phosphate isomerase	227
647044732	156	59.6	6	156	3	150	8.0e-61	226	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
647044733	196	34.76	1	184	1	184	3.0e-37	148	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
647044735	99	34.74	4	98	1	95	2.0e-13	67.6	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
647044737	180	43.6	1	169	3	173	2.0e-36	145	COG3079	Uncharacterized conserved protein YgfB, UPF0149 family	186
647044738	446	32.68	19	424	3	374	2.0e-70	260	COG0006	Xaa-Pro aminopeptidase	384
647044740	441	22.94	12	436	8	376	6.0e-36	145	COG0006	Xaa-Pro aminopeptidase	384
647044744	385	44.3	5	384	31	410	2.0e-111	396	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
647044745	199	52.02	1	197	1	193	2.0e-62	232	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
647044747	240	58.65	5	240	9	230	1.0e-75	275	COG0689	Ribonuclease PH	230
647044748	286	50.69	1	286	1	290	3.0e-77	281	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
647044749	203	49.2	2	188	3	188	4.0e-68	250	COG0194	Guanylate kinase	191
647044750	99	48.65	1	74	1	74	5.0e-12	62.6	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
647044751	723	44.35	28	722	13	700	0.0e+00	832	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
647044752	126	50.39	1	126	3	129	8.0e-34	135	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
647044753	717	55.54	17	709	10	676	0.0e+00	859	COG1200	RecG-like helicase	677
647044754	312	40.13	4	311	2	309	3.0e-73	269	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
647044755	80	40	1	79	1	68	1.0e-17	81.5	COG0254	Ribosomal protein L31	75
647044757	429	55.2	27	429	1	390	0.0e+00	480	COG0372	Citrate synthase	390
647044759	808	48.42	6	788	3	752	0.0e+00	873	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
647044760	352	51.14	2	352	3	354	9.0e-113	400	COG4972	Tfp pilus assembly protein, ATPase PilM	354
647044761	260	43.45	1	168	4	171	6.0e-43	167	COG3166	Tfp pilus assembly protein PilN	206
647044762	221	45.54	1	213	1	204	3.0e-63	234	COG3167	Tfp pilus assembly protein PilO	211
647044763	177	47.13	7	176	3	168	1.0e-48	186	COG3168	Tfp pilus assembly protein PilP	170
647044764	652	33.03	4	647	109	709	3.0e-114	406	COG4796	Type II secretory pathway, component HofQ	709
647044766	339	44.06	27	339	18	328	9.0e-64	237	COG0714	MoxR-like ATPase	329
647044769	335	23.55	67	291	44	255	4.0e-08	52.6	COG1240	Mg-chelatase subunit ChlD	261
647044772	426	36.67	8	425	2	398	1.0e-77	283	COG1301	Na+/H+-dicarboxylate symporter	415
647044773	666	60.12	1	666	1	661	0.0e+00	1015	COG0021	Transketolase	663
647044774	728	42.9	3	728	2	719	0.0e+00	659	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
647044775	325	33	25	322	2	297	1.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
647044776	255	33.86	5	254	3	251	3.0e-34	139	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647044778	293	27.07	69	290	1	227	7.0e-22	98	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
647044780	904	16.36	266	904	184	768	3.0e-15	78	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647044782	652	19.02	30	559	1	488	9.0e-39	155	COG0427	Acyl-CoA hydrolase	501
647044783	121	45.45	1	120	2	122	2.0e-28	117	COG3682	Predicted transcriptional regulator	123
647044784	432	30.34	7	289	8	327	2.0e-34	140	COG4219	Signal transducer regulating beta-lactamase production, contains  metallopeptidase domain	337
647044787	230	58.45	5	223	2	219	1.0e-64	239	COG4149	ABC-type molybdate transport system, permease component	225
647044788	258	41.7	10	255	13	255	1.0e-51	196	COG0725	ABC-type molybdate transport system, periplasmic component	258
647044789	276	28.5	1	208	10	213	2.0e-22	100	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647044791	204	28.85	3	199	2	208	1.0e-25	109	COG3047	Outer membrane protein W	213
647044792	154	40.74	2	154	53	213	2.0e-32	131	COG3047	Outer membrane protein W	213
647044797	336	55.02	5	332	3	324	3.0e-121	428	COG0158	Fructose-1,6-bisphosphatase	326
647044810	132	31.34	3	131	4	136	1.0e-13	68.9	COG5622	Protein required for attachment to host cells	139
647044811	373	32.11	72	362	20	311	2.0e-24	107	COG0657	Acetyl esterase/lipase	312
647044812	161	37.01	17	143	1	123	1.0e-18	86.2	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
647044820	218	36.24	1	212	6	223	2.0e-34	138	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
647044821	831	31.6	24	831	15	808	0.0e+00	535	COG1205	ATP-dependent helicase YprA,  contains C-terminal metal-binding DUF1998 domain	851
647044822	485	27.49	260	468	67	265	2.0e-25	110	COG3359	Uncharacterized conserved protein YprB, contains RNaseH-like and TPR domains	278
647044825	382	26.2	85	381	1	310	4.0e-28	119	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
647044826	261	30.74	22	260	5	237	9.0e-37	147	COG5255	Uncharacterized protein	239
647044832	581	25.79	4	340	1	330	1.0e-27	118	COG4219	Signal transducer regulating beta-lactamase production, contains  metallopeptidase domain	337
647044833	128	25.62	5	125	3	123	8.0e-14	69.5	COG3682	Predicted transcriptional regulator	123
647044838	395	44.35	50	387	15	352	2.0e-83	303	COG3569	DNA topoisomerase IB	354
647044840	1490	58.46	710	1184	5	482	0.0e+00	628	COG0069	Glutamate synthase domain 2	485
647044841	493	45.01	25	485	1	455	3.0e-130	459	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
647044844	352	45.85	1	347	1	339	1.0e-115	409	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
647044846	357	24.57	44	357	47	396	4.0e-33	135	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
647044849	349	22.77	36	344	47	391	7.0e-28	118	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
647044851	312	26.01	6	291	77	396	3.0e-30	125	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
647044853	603	27.85	140	569	4	435	4.0e-54	206	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
647044855	432	34.88	22	431	11	420	2.0e-71	263	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
647044856	514	42.93	10	409	2	400	7.0e-96	345	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
647044857	330	38.36	25	322	23	324	2.0e-57	215	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
647044858	106	63.89	1	106	1	107	2.0e-37	147	COG4517	Uncharacterized protein	109
647044859	230	28.64	15	227	18	220	3.0e-16	78.6	COG0705	Membrane associated serine protease, rhomboid family	228
647044860	434	34.94	2	434	9	440	2.0e-90	326	COG2067	Long-chain fatty acid transport protein	440
647044863	364	43.2	38	331	1	289	3.0e-78	285	COG1533	DNA repair photolyase	297
647044864	486	37.7	57	486	1	438	2.0e-71	263	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
647044866	255	39.76	3	253	1	243	1.0e-64	239	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
647044867	137	37.5	1	135	1	131	3.0e-26	110	COG0848	Biopolymer transport protein ExbD	137
647044868	140	39.29	1	139	1	137	1.0e-29	122	COG0848	Biopolymer transport protein ExbD	137
647044869	253	38.5	41	253	8	216	3.0e-36	145	COG0811	Biopolymer transport protein ExbB/TolQ	216
647044870	190	29.38	1	190	34	244	3.0e-09	55.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
647044871	397	20.53	89	381	101	389	1.0e-06	48.4	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
647044874	814	61.24	15	577	6	567	0.0e+00	878	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
647044875	368	34.6	1	362	1	362	4.0e-76	278	COG1195	Recombinational DNA repair ATPase RecF	363
647044877	366	40.33	1	366	1	364	2.0e-91	329	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
647044878	442	50.8	4	438	1	408	1.0e-130	460	COG0593	Chromosomal replication initiation ATPase DnaA	408
647044880	145	31.62	10	124	1	117	3.0e-15	74.5	COG0594	RNase P protein component	117
647044881	574	40.71	272	574	4	309	2.0e-67	250	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
647044883	446	47.33	7	446	6	454	0.0e+00	477	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
647044885	768	17.41	6	768	25	768	6.0e-20	93.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647044886	365	29.34	29	362	5	257	1.0e-33	137	COG0584	Glycerophosphoryl diester phosphodiesterase	257
647044887	241	25.48	2	185	14	221	2.0e-11	63.2	COG0705	Membrane associated serine protease, rhomboid family	228
647044888	318	29.27	75	315	16	248	5.0e-39	155	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
647044889	388	40.87	9	388	6	393	1.0e-106	380	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
647044891	509	31.97	132	496	3	313	6.0e-58	219	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
647044892	436	19.09	17	427	22	432	2.0e-22	100	COG2271	Sugar phosphate permease	448
647044893	389	62.43	1	378	1	378	0.0e+00	476	COG1929	Glycerate kinase	378
647044895	396	47.63	4	382	3	375	2.0e-95	343	COG3835	Sugar diacid utilization regulator	376
647044898	818	32.62	21	808	33	760	7.0e-119	422	COG3537	Putative alpha-1,2-mannosidase	768
647044899	471	32.27	28	460	17	442	2.0e-38	154	COG0531	Amino acid transporter	466
647044902	307	28.24	3	298	2	296	5.0e-25	108	COG0583	DNA-binding transcriptional regulator, LysR family	297
647044903	335	34.32	1	333	1	325	1.0e-58	220	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647044904	526	32.49	82	512	8	425	2.0e-69	256	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
647044907	193	50.56	13	192	1	161	2.0e-60	225	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
647044912	351	43.57	96	336	10	249	2.0e-75	276	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
647044913	96	36.96	7	95	8	99	8.0e-09	52.2	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
647044914	220	32.54	3	209	1	202	2.0e-38	152	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
647044916	249	45.38	1	249	17	264	8.0e-58	216	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
647044917	264	50.96	1	259	1	261	2.0e-87	315	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
647044919	185	24.65	25	163	10	149	6.0e-09	54.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
647044920	178	41.38	3	176	2	168	2.0e-36	145	COG4675	Microcystin-dependent protein  (function unknown)	170
647044921	175	51.46	4	174	3	169	3.0e-42	164	COG4675	Microcystin-dependent protein  (function unknown)	170
647044922	183	46.99	2	183	1	170	1.0e-37	149	COG4675	Microcystin-dependent protein  (function unknown)	170
647044925	1137	33.61	8	1081	1	1048	0.0e+00	746	COG1330	Exonuclease V gamma subunit	1078
647044928	746	28.33	209	714	200	692	2.0e-71	264	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
647044945	1051	14.97	476	1051	218	768	1.0e-15	79.6	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647044947	246	39.84	1	245	1	246	3.0e-62	231	COG1291	Flagellar motor component MotA	266
647044948	324	31.52	1	274	1	243	3.0e-44	172	COG1360	Flagellar motor protein MotB	244
647044949	260	35.86	1	249	2	251	2.0e-46	179	COG1192	Cellulose biosynthesis protein BcsQ	259
647044950	363	37.31	229	362	20	152	1.0e-23	104	COG0835	Chemotaxis signal transduction protein	165
647044957	432	24.15	3	209	2	207	2.0e-18	87.3	COG5278	Extracellular (periplasmic) sensor domain CHASE3 (specificity unknown)	207
647044979	365	50.82	1	364	1	368	0.0e+00	464	COG2812	DNA polymerase III, gamma/tau subunits	515
647044983	106	54.37	3	103	5	105	1.0e-23	101	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
647044984	197	54.59	1	196	3	198	1.0e-75	275	COG0353	Recombinational DNA repair protein RecR	198
647044985	116	41.74	2	116	1	113	4.0e-25	106	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
647044986	166	38.46	2	166	18	177	4.0e-42	164	COG3065	Starvation-inducible outer membrane lipoprotein	191
647044988	318	27.81	39	316	2	301	8.0e-19	88.3	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
647044989	317	43.03	9	316	5	327	2.0e-63	236	COG0714	MoxR-like ATPase	329
647044990	612	19.55	9	435	21	461	5.0e-22	99.8	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
647044993	580	40.77	11	580	4	554	7.0e-126	444	COG2831	Hemolysin activation/secretion protein	554
647044997	232	33.33	2	227	9	236	2.0e-48	185	COG2188	DNA-binding transcriptional regulator, GntR family	236
647045001	269	21.84	42	213	3	167	7.0e-12	64.6	COG1716	Forkhead associated (FHA) domain, binds pSer, pThr, pTyr	191
647045002	190	51.61	2	187	24	209	8.0e-43	166	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
647045003	322	40.86	20	285	1	264	1.0e-59	223	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
647045005	308	50.96	1	308	56	365	3.0e-101	361	COG1932	Phosphoserine aminotransferase	365
647045007	402	47.46	131	401	2	276	2.0e-90	326	COG0077	Prephenate dehydratase	279
647045008	474	45.41	43	457	6	417	1.0e-115	409	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
647045010	220	29.21	52	219	67	244	4.0e-13	68.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
647045011	426	57.11	1	426	1	426	0.0e+00	577	COG0172	Seryl-tRNA synthetase	429
647045012	200	44.22	7	192	2	200	3.0e-54	204	COG1182	FMN-dependent NADH-azoreductase	202
647045014	310	29.54	1	278	23	297	7.0e-29	121	COG0583	DNA-binding transcriptional regulator, LysR family	297
647045025	341	18.91	149	332	9	209	2.0e-08	54	COG0705	Membrane associated serine protease, rhomboid family	228
647045030	623	33.52	300	623	2	344	3.0e-37	150	COG0840	Methyl-accepting chemotaxis protein	408
647045032	889	37.65	557	871	69	408	2.0e-51	198	COG0840	Methyl-accepting chemotaxis protein	408
647045034	265	21.39	64	261	37	228	1.0e-11	64.1	COG5581	c-di-GMP-binding flagellar brake protein YcgR, contains PilZNR and PilZ domains	233
647045035	160	48.2	13	151	19	157	3.0e-38	151	COG0835	Chemotaxis signal transduction protein	165
647045037	772	35.22	364	738	3	408	1.0e-47	185	COG0840	Methyl-accepting chemotaxis protein	408
647045038	288	45.99	19	283	1	268	6.0e-69	254	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
647045039	198	45.51	15	166	2	157	3.0e-44	171	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
647045040	358	51.27	7	358	2	347	5.0e-101	361	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
647045043	271	30.71	4	268	5	281	9.0e-19	87.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647045044	863	77.66	1	861	1	850	0.0e+00	1482	COG1049	Aconitase B	852
647045045	136	26.87	1	129	3	127	5.0e-06	43.6	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
647045047	922	62.6	3	918	1	861	0.0e+00	1249	COG1048	Aconitase A	861
647045050	560	38.88	15	557	1	524	0.0e+00	479	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647045062	591	34.87	23	450	11	443	4.0e-62	232	COG0038	H+/Cl- antiporter ClcA	443
647045073	587	24.43	1	584	18	612	7.0e-49	189	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
647045076	224	25.98	14	206	47	244	1.0e-22	100	COG1360	Flagellar motor protein MotB	244
647045084	387	36.41	1	387	1	350	1.0e-75	277	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
647045087	582	36.62	7	574	5	567	1.0e-114	407	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647045089	395	52.02	21	382	1	370	0.0e+00	473	COG0562	UDP-galactopyranose mutase	374
647045091	305	49.4	2	250	81	329	3.0e-99	355	COG1087	UDP-glucose 4-epimerase	329
647045093	288	41.13	42	284	3	249	9.0e-52	197	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647045096	340	43.73	6	338	6	346	1.0e-69	256	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
647045097	469	44.88	1	452	2	457	5.0e-124	438	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
647045100	426	39.33	8	421	9	451	5.0e-100	358	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
647045103	1180	39.41	224	488	2	268	1.0e-64	242	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
647045106	299	42.6	1	277	1	271	8.0e-74	270	COG3546	Mn-containing catalase (includes spore coat protein CotJC)	277
647045108	168	58.08	1	167	1	167	2.0e-44	171	COG3685	Ferritin-like metal-binding protein YciE	167
647045111	404	16.83	121	403	2	301	3.0e-07	49.9	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647045114	258	35.29	3	256	1	238	3.0e-41	162	COG3279	DNA-binding response regulator, LytR/AlgR family	244
647045120	308	39.42	30	299	21	293	3.0e-56	212	COG3662	Uncharacterized conserved protein, DUF2236 family	300
647045121	701	42.3	47	701	6	654	0.0e+00	610	COG3590	Predicted metalloendopeptidase	654
647045122	231	22.46	1	230	4	233	9.0e-14	70.6	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
647045123	331	41.12	1	318	1	315	9.0e-85	307	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
647045124	189	30.66	1	189	3	207	5.0e-25	107	COG0655	Multimeric flavodoxin WrbA	207
647045125	298	35.55	3	297	2	296	5.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
647045126	136	36.84	4	134	5	135	4.0e-07	47.3	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
647045127	272	41.57	1	262	6	268	1.0e-63	237	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
647045128	419	59.12	8	418	3	404	0.0e+00	519	COG4277	Predicted DNA-binding protein with the Helix-hairpin-helix motif	404
647045129	481	34.16	271	466	1	199	3.0e-36	146	COG1573	Uracil-DNA glycosylase	202
647045132	185	48.92	1	185	8	181	3.0e-37	147	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
647045137	769	53.79	1	431	12	432	0.0e+00	554	COG0281	Malic enzyme	432
647045138	457	52.02	15	430	3	405	2.0e-102	366	COG1301	Na+/H+-dicarboxylate symporter	415
647045139	390	30.96	10	390	23	426	3.0e-82	299	COG3746	Phosphate-selective porin	426
647045142	425	23.73	15	364	28	350	1.0e-09	57.9	COG2814	Predicted arabinose efflux permease, MFS family	394
647045143	259	26.89	3	258	1	258	5.0e-22	98.1	COG0725	ABC-type molybdate transport system, periplasmic component	258
647045144	300	31.4	5	294	1	289	3.0e-38	152	COG0583	DNA-binding transcriptional regulator, LysR family	297
647045145	356	42.25	9	334	2	316	4.0e-78	285	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
647045146	181	30.47	44	170	6	132	2.0e-19	89.2	COG3631	Ketosteroid isomerase-related protein	133
647045148	212	39.11	6	203	3	203	6.0e-44	170	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
647045149	349	23.33	50	342	1	293	2.0e-30	126	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
647045150	461	31.31	163	457	34	328	3.0e-38	153	COG0642	Signal transduction histidine kinase	336
647045151	233	41.74	1	222	1	229	1.0e-51	196	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647045152	397	27.91	21	397	42	426	2.0e-73	269	COG3746	Phosphate-selective porin	426
647045154	442	63.57	1	441	1	433	0.0e+00	535	COG2851	Mg2+/citrate symporter	433
647045155	246	39.44	1	243	3	250	2.0e-37	149	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647045156	343	38.51	14	342	1	328	7.0e-69	254	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
647045157	439	17.85	1	391	2	385	3.0e-11	63.3	COG2211	Na+/melibiose symporter or related transporter	467
647045158	818	18.91	22	818	27	768	4.0e-22	100	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647045159	638	21.32	94	597	4	492	3.0e-33	137	COG0366	Glycosidase	505
647045160	226	27.88	20	225	11	183	3.0e-21	95.2	COG0693	Putative intracellular protease/amidase	188
647045162	363	36.66	34	336	1	298	8.0e-69	254	COG1162	Putative ribosome biogenesis GTPase RsgA	301
647045163	423	36.39	14	408	2	393	2.0e-83	303	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
647045164	216	22.06	9	207	10	213	5.0e-09	54.5	COG2755	Lysophospholipase L1 or related esterase	216
647045167	260	34.54	75	260	65	256	3.0e-25	108	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
647045168	273	53	5	103	2	101	1.0e-36	146	COG0278	Glutaredoxin-related protein	105
647045171	212	57.23	32	204	9	181	4.0e-55	207	COG3803	Uncharacterized conserved protein, DUF924 family	182
647045172	469	28.27	45	450	13	403	4.0e-49	189	COG1228	Imidazolonepropionase or related amidohydrolase	406
647045173	426	22.77	21	398	2	398	4.0e-16	79.6	COG1228	Imidazolonepropionase or related amidohydrolase	406
647045186	276	41.56	1	276	7	314	3.0e-73	268	COG0627	S-formylglutathione hydrolase FrmB	316
647045187	369	72.63	1	369	1	366	0.0e+00	582	COG1062	Zn-dependent alcohol dehydrogenase	366
647045188	91	48.89	1	90	1	89	2.0e-18	84.1	COG1937	DNA-binding transcriptional regulator, FrmR family	89
647045191	239	44.1	6	232	1	225	2.0e-52	198	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647045192	499	25.75	183	499	5	333	1.0e-38	154	COG0642	Signal transduction histidine kinase	336
647045196	525	56.92	74	525	2	456	0.0e+00	609	COG3572	Gamma-glutamylcysteine synthetase	456
647045197	188	46.41	1	181	19	199	2.0e-61	228	COG0218	GTP-binding protein EngB required for normal cell division	200
647045198	265	42.27	51	146	22	115	1.0e-13	70.8	COG2863	Cytochrome c553	121
647045199	216	23.24	21	203	64	240	1.0e-08	53.3	COG1651	Protein-disulfide isomerase	244
647045200	271	20.77	7	263	1	244	1.0e-07	51	COG1651	Protein-disulfide isomerase	244
647045201	255	30.04	12	250	1	258	6.0e-40	157	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
647045202	456	49.03	1	412	64	469	1.0e-124	439	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647045204	174	30.12	23	169	11	174	3.0e-17	81.6	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
647045206	257	39.02	8	252	3	234	8.0e-46	177	COG1183	Phosphatidylserine synthase	234
647045208	564	43.03	1	562	1	498	0.0e+00	544	COG0442	Prolyl-tRNA synthetase	500
647045209	152	25.2	1	122	5	127	1.0e-14	72.3	COG2916	DNA-binding protein H-NS	128
647045210	419	30.61	13	256	10	250	7.0e-42	165	COG2966	Uncharacterized membrane protein YjjP, DUF1212 family	250
647045211	370	42.28	99	370	1	267	5.0e-70	258	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
647045213	280	52.34	17	272	2	256	9.0e-95	340	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
647045214	308	26.28	1	299	1	305	1.0e-31	130	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
647045215	214	40.78	4	204	1	205	2.0e-46	179	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
647045218	199	34.22	4	187	11	194	7.0e-32	130	COG3145	Alkylated DNA repair dioxygenase AlkB	194
647045219	549	31.17	19	460	2	396	1.0e-62	234	COG0644	Dehydrogenase (flavoprotein)	396
647045221	212	65.88	3	212	6	216	4.0e-79	287	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
647045222	243	59.17	12	229	3	219	1.0e-81	296	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
647045223	448	36.76	1	447	5	458	3.0e-102	365	COG1109	Phosphomannomutase	464
647045224	467	56.16	4	330	2	333	0.0e+00	474	COG0836	Mannose-1-phosphate guanylyltransferase	333
647045225	302	46.98	1	298	1	281	2.0e-84	306	COG1091	dTDP-4-dehydrorhamnose reductase	281
647045226	185	55.17	1	174	1	173	6.0e-60	223	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
647045227	295	57.29	4	291	1	285	2.0e-114	405	COG1209	dTDP-glucose pyrophosphorylase	286
647045228	351	62	3	349	2	338	0.0e+00	537	COG1088	dTDP-D-glucose 4,6-dehydratase	340
647045229	248	49.03	1	248	1	259	5.0e-64	237	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
647045231	314	47	2	314	1	311	2.0e-79	289	COG2025	Electron transfer flavoprotein, alpha subunit	313
647045232	314	18.33	8	314	19	320	9.0e-07	47.7	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
647045233	464	25.93	173	464	7	289	1.0e-27	118	COG0382	4-hydroxybenzoate polyprenyltransferase	289
647045234	433	18.49	35	430	59	457	3.0e-29	123	COG0277	FAD/FMN-containing dehydrogenase	459
647045235	242	21.6	1	240	6	255	2.0e-25	109	COG0300	Short-chain dehydrogenase	265
647045236	314	22.48	7	233	2	255	2.0e-18	86.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647045237	421	23.42	1	419	11	444	3.0e-53	202	COG1232	Protoporphyrinogen oxidase	444
647045238	134	20.61	3	131	10	138	4.0e-07	47.6	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
647045247	629	45.44	1	627	2	632	0.0e+00	816	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
647045249	554	63.42	2	543	1	530	0.0e+00	857	COG0504	CTP synthase (UTP-ammonia lyase)	533
647045251	276	63.6	1	272	5	276	3.0e-125	441	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
647045253	430	66.12	1	428	1	423	0.0e+00	631	COG0148	Enolase	423
647045254	121	52.58	1	97	21	117	4.0e-26	110	COG2919	Cell division protein FtsB	117
647045255	269	45.26	1	230	1	229	3.0e-60	225	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
647045256	163	60.51	5	161	1	157	7.0e-61	226	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
647045257	369	31.46	1	352	6	395	1.0e-66	246	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
647045258	179	39.66	2	179	4	181	3.0e-34	138	COG2840	DNA-nicking endonuclease, Smr domain	184
647045259	259	56.57	1	247	1	250	2.0e-86	312	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
647045260	225	51.71	20	223	1	205	7.0e-62	230	COG2518	Protein-L-isoaspartate O-methyltransferase	209
647045261	204	29.17	3	170	1	159	8.0e-20	90.7	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
647045262	257	30.98	28	257	13	267	2.0e-28	119	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
647045263	124	35.48	1	122	5	127	3.0e-26	110	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
647045264	101	50	5	100	2	97	4.0e-25	106	COG1534	RNA-binding protein YhbY	97
647045265	210	57.43	5	206	1	202	2.0e-69	255	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
647045266	646	60.43	9	614	1	596	0.0e+00	789	COG0465	ATP-dependent Zn proteases	596
647045267	300	46.27	20	284	8	270	1.0e-72	266	COG0294	Dihydropteroate synthase	274
647045268	327	53.16	6	306	2	295	4.0e-92	331	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
647045269	92	67.57	1	73	1	74	2.0e-25	107	COG1923	sRNA-binding regulator protein Hfq	77
647045270	439	53.65	6	401	1	391	3.0e-120	425	COG2262	50S ribosomal subunit-associated GTPase HflX	411
647045272	164	53.46	6	164	3	160	5.0e-47	180	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
647045273	558	37.86	7	519	3	509	2.0e-109	390	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
647045274	213	40.93	1	213	2	201	7.0e-44	170	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
647045275	344	60.63	1	283	3	279	1.0e-83	303	COG0468	RecA/RadA recombinase	279
647045276	162	35.67	1	155	6	160	3.0e-23	101	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
647045277	882	55.21	2	881	1	879	0.0e+00	1171	COG0013	Alanyl-tRNA synthetase	879
647045278	70	64.29	1	56	1	56	1.0e-18	85	COG1551	sRNA-binding carbon storage regulator CsrA	73
647045281	233	38.27	1	232	1	243	1.0e-45	176	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
647045284	329	28.92	1	201	8	206	1.0e-23	104	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
647045286	293	24.15	12	270	12	269	4.0e-14	72.3	COG4757	Predicted alpha/beta hydrolase	281
647045287	269	52.02	9	254	6	251	4.0e-75	274	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
647045290	465	48.71	4	465	1	436	0.0e+00	522	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
647045291	160	55.33	9	158	9	156	8.0e-51	192	COG1225	Peroxiredoxin	157
647045293	208	42.05	32	207	1	176	3.0e-55	208	COG2716	Glycine cleavage system regulatory protein	176
647045294	302	43.58	1	293	3	298	6.0e-72	264	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
647045296	107	39.71	2	65	3	68	1.0e-09	54.8	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
647045297	292	40.73	2	292	8	305	5.0e-60	224	COG3734	2-keto-3-deoxy-galactonokinase	306
647045298	291	37.59	4	288	23	307	1.0e-58	220	COG3386	Sugar lactone lactonase YvrE	307
647045299	349	38.84	3	326	52	365	8.0e-68	251	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
647045301	210	30.81	1	210	1	210	2.0e-42	165	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
647045303	323	29.47	14	314	1	296	5.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
647045311	299	53.87	10	293	6	289	2.0e-99	355	COG1946	Acyl-CoA thioesterase	289
647045314	142	36.23	4	141	10	146	6.0e-26	110	COG2847	Copper(I)-binding protein	151
647045315	134	36.22	9	132	7	130	9.0e-25	105	COG0824	Acyl-CoA thioesterase FadM	137
647045316	988	67.8	1	943	1	935	0.0e+00	1572	COG0178	Excinuclease UvrABC ATPase subunit	935
647045317	106	51.46	1	102	1	103	4.0e-30	122	COG0261	Ribosomal protein L21	103
647045318	86	72.09	1	86	1	85	7.0e-30	121	COG0211	Ribosomal protein L27	87
647045319	350	58.86	1	349	1	345	0.0e+00	487	COG0536	GTPase involved in cell partioning and DNA repair	369
647045320	89	53.41	1	88	1	88	6.0e-12	62.6	COG0268	Ribosomal protein S20	88
647045321	534	44.22	1	533	9	516	1.0e-107	383	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
647045322	333	44.22	15	307	14	304	5.0e-86	311	COG0196	FAD synthase	304
647045323	943	46.42	3	937	1	933	0.0e+00	1170	COG0060	Isoleucyl-tRNA synthetase	933
647045325	172	41.98	1	160	2	159	1.0e-37	149	COG0597	Lipoprotein signal peptidase	167
647045326	316	66.33	1	297	2	294	2.0e-126	445	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
647045328	311	47.64	15	268	5	247	4.0e-68	251	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
647045329	666	56.77	43	608	5	566	0.0e+00	630	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
647045330	210	45.97	1	210	1	209	9.0e-47	180	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
647045331	111	52.25	1	111	1	110	2.0e-21	94.1	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
647045332	565	24.7	10	565	9	557	3.0e-80	293	COG3975	Predicted metalloprotease, contains C-terminal PDZ domain	558
647045333	463	61.56	1	463	1	455	0.0e+00	636	COG1066	Predicted ATP-dependent serine protease	456
647045334	128	38.76	1	127	1	120	5.0e-21	93.4	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
647045335	249	34.09	4	221	9	226	5.0e-29	121	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647045337	476	27.42	353	476	1	121	7.0e-09	55.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647045338	626	22.15	13	626	5	620	1.0e-119	423	COG0326	Molecular chaperone, HSP90 family	623
647045342	285	37.07	160	275	2	117	2.0e-16	80.1	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
647045343	120	32.14	4	114	5	116	1.0e-09	55.4	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
647045344	131	31.16	3	131	6	143	7.0e-17	79.6	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
647045345	337	25	19	140	15	142	9.0e-06	45	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
647045346	291	34.32	20	288	76	336	4.0e-39	155	COG0642	Signal transduction histidine kinase	336
647045351	121	57.26	1	117	1	117	2.0e-38	150	COG5507	Uncharacterized  conserved protein YbaA, DUF1428 family	117
647045355	274	29.75	8	274	1	267	3.0e-41	162	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
647045356	1057	32.72	267	589	18	328	6.0e-40	160	COG0642	Signal transduction histidine kinase	336
647045359	527	35.24	35	526	1	498	0.0e+00	469	COG3534	Alpha-L-arabinofuranosidase	501
647045361	349	35.61	3	333	1	307	6.0e-53	201	COG2017	Galactose mutarotase or related enzyme	308
647045362	263	41.22	1	260	2	263	4.0e-53	201	COG4137	ABC-type uncharacterized transport system, permease component	265
647045363	446	59.42	1	445	13	451	0.0e+00	588	COG0541	Signal recognition particle GTPase	451
647045364	357	36.47	11	357	7	331	5.0e-44	172	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
647045365	274	24.58	14	238	10	248	3.0e-19	89.3	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
647045366	85	56.47	1	85	1	84	1.0e-24	104	COG0228	Ribosomal protein S16	87
647045367	170	39.31	1	170	1	172	6.0e-44	170	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
647045368	252	53.91	1	243	1	240	1.0e-92	332	COG0336	tRNA G37 N-methylase TrmD	240
647045369	135	58.77	5	118	2	115	3.0e-38	150	COG0335	Ribosomal protein L19	115
647045370	491	36.28	4	443	13	447	9.0e-64	238	COG0534	Na+-driven multidrug efflux pump	455
647045372	135	50	8	97	6	95	8.0e-20	89.6	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
647045373	748	75.43	1	748	12	730	0.0e+00	1212	COG0376	Catalase (peroxidase I)	730
647045376	815	46.56	37	813	77	843	0.0e+00	826	COG0249	DNA mismatch repair ATPase MutS	843
647045377	643	27.16	35	485	3	430	9.0e-48	185	COG3669	Alpha-L-fucosidase	430
647045380	403	36.22	27	380	36	403	2.0e-68	253	COG3867	Arabinogalactan endo-1,4-beta-galactosidase	403
647045382	280	55.68	3	274	43	315	2.0e-89	322	COG3800	Predicted transcriptional regulator	332
647045384	501	41.88	8	484	1	469	2.0e-116	413	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647045385	393	48.05	13	386	4	387	5.0e-89	321	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647045386	265	42.41	9	262	4	257	2.0e-45	176	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647045387	391	30.73	6	209	1	181	3.0e-27	116	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647045389	331	50.69	11	300	7	296	2.0e-81	295	COG1230	Co/Zn/Cd efflux system component	296
647045390	693	38.73	316	588	2	285	9.0e-61	228	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
647045391	206	36.17	10	197	1	182	6.0e-27	114	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
647045392	221	27.31	12	221	1	208	4.0e-13	68.5	COG3073	Negative regulator of sigma E activity	213
647045394	528	51.79	129	407	62	339	1.0e-68	254	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
647045395	596	67.84	1	596	6	602	0.0e+00	1043	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
647045396	266	28.93	43	152	7	165	9.0e-16	77.7	COG0681	Signal peptidase I	166
647045398	227	47.47	13	224	15	230	6.0e-64	237	COG0571	dsRNA-specific ribonuclease	235
647045399	285	48.95	2	285	12	296	1.0e-98	353	COG1159	GTPase Era, involved in 16S rRNA processing	298
647045400	240	30.67	5	236	7	243	6.0e-33	134	COG1381	Recombinational DNA repair protein (RecF pathway)	251
647045402	444	36.22	10	437	2	432	1.0e-100	360	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
647045403	165	51.53	1	163	1	156	1.0e-57	215	COG2954	CYTH domain, found in class IV adenylate cyclase and various triphosphatases	156
647045404	241	38.42	1	202	6	207	7.0e-43	167	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
647045405	336	34.77	10	325	4	327	6.0e-56	211	COG3380	Predicted NAD/FAD-dependent oxidoreductase	331
647045407	530	44.99	24	530	4	505	0.0e+00	532	COG3046	Uncharacterized protein related to deoxyribodipyrimidine photolyase	505
647045408	334	42.37	2	291	8	293	2.0e-66	246	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
647045409	184	33.71	8	184	3	176	5.0e-46	177	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
647045410	256	42.45	10	250	15	255	2.0e-61	229	COG0005	Purine nucleoside phosphorylase	262
647045411	68	59.7	1	67	1	67	1.0e-25	107	COG1278	Cold shock protein, CspA family	67
647045412	421	26.53	5	388	3	386	2.0e-39	156	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647045413	214	31.61	9	190	2	191	1.0e-18	86.9	COG1407	Metallophosphoesterase superfamily enzyme	235
647045414	833	28.33	16	830	13	800	0.0e+00	494	COG1201	Lhr-like helicase	814
647045415	534	31.65	134	533	42	443	3.0e-57	216	COG1793	ATP-dependent DNA ligase	444
647045417	340	21.84	15	334	18	418	6.0e-34	138	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
647045423	391	41.4	1	388	1	388	1.0e-78	286	COG0183	Acetyl-CoA acetyltransferase	392
647045425	920	28.97	389	920	1	577	5.0e-51	196	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
647045426	366	29.38	1	349	28	408	3.0e-70	259	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
647045429	166	27.33	1	160	51	220	6.0e-21	93.6	COG1451	Predicted metal-dependent hydrolase	223
647045433	88	30.59	1	76	36	120	6.0e-12	62.4	COG1734	RNA polymerase-binding transcription factor DksA	120
647045439	157	47.4	1	152	1	153	3.0e-38	151	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
647045440	349	27.93	40	329	14	287	6.0e-38	151	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
647045441	111	46.9	2	111	1	112	4.0e-31	126	COG2824	Uncharacterized Zn-ribbon-containing protein	112
647045442	391	42.16	34	391	4	360	3.0e-87	316	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
647045443	403	37.91	7	396	2	393	2.0e-66	246	COG2814	Predicted arabinose efflux permease, MFS family	394
647045446	200	25.95	27	200	2	179	7.0e-19	87.3	COG1514	2'-5' RNA ligase	180
647045447	201	35.08	11	201	22	204	9.0e-26	110	COG4339	Predicted metal-dependent phosphohydrolase, HD superfamily	208
647045449	456	41.63	1	453	1	448	1.0e-108	387	COG3946	Type IV secretory pathway, VirJ component	456
647045450	854	47.83	324	850	2	532	0.0e+00	527	COG2898	Lysylphosphatidylglycerol synthetase, C-terminal domain, DUF2156 family	538
647045452	115	31.4	1	115	9	129	5.0e-25	106	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
647045454	356	25.84	59	352	1	283	1.0e-51	197	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
647045455	260	32.95	2	260	12	269	9.0e-44	170	COG3752	Steroid 5-alpha reductase family enzyme	272
647045457	431	41.1	124	415	2	283	7.0e-77	281	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
647045458	294	36.78	28	288	4	249	8.0e-56	210	COG3496	Uncharacterized conserved protein, DUF1365 family	261
647045459	416	44.12	5	416	10	425	8.0e-118	417	COG2907	Predicted NAD/FAD-binding protein	447
647045460	401	40.07	122	391	20	283	2.0e-58	220	COG1398	Fatty-acid desaturase	289
647045461	277	36.8	1	268	1	235	2.0e-31	129	COG5343	Anti-sigma-K factor RskA	240
647045462	187	32.58	11	187	1	177	5.0e-23	100	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
647045468	196	24.74	1	189	5	183	2.0e-18	85.8	COG0560	Phosphoserine phosphatase	212
647045470	692	40.71	1	548	3	558	0.0e+00	614	COG0143	Methionyl-tRNA synthetase	558
647045472	128	29.29	4	126	2	138	7.0e-08	49.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
647045473	465	42.17	13	455	43	499	0.0e+00	473	COG0833	Amino acid permease	541
647045474	321	49.83	24	317	11	295	4.0e-82	298	COG2040	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)	300
647045475	647	42.08	85	643	21	587	0.0e+00	578	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
647045478	258	30.68	62	237	56	220	2.0e-19	89.2	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
647045479	204	38.16	1	203	14	210	4.0e-47	181	COG2928	Uncharacterized membrane protein	222
647045482	101	33.66	1	100	10	108	1.0e-12	64.5	COG1695	DNA-binding transcriptional regulator, PadR family	138
647045484	438	52.42	4	416	1	408	0.0e+00	547	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
647045486	148	41.61	1	148	5	149	6.0e-32	129	COG1981	Uncharacterized membrane protein	149
647045488	251	35.66	3	246	4	247	2.0e-48	185	COG4700	Uncharacterized protein	251
647045489	319	66.77	2	317	1	316	0.0e+00	502	COG0825	Acetyl-CoA carboxylase alpha subunit	317
647045491	1196	45.46	3	1179	1	1130	0.0e+00	1235	COG0587	DNA polymerase III, alpha subunit	1139
647045492	242	53.89	32	222	1	193	6.0e-66	244	COG0164	Ribonuclease HII	199
647045493	439	50.52	44	422	1	379	2.0e-128	452	COG0763	Lipid A disaccharide synthetase	381
647045494	263	48.28	3	263	1	260	2.0e-98	352	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
647045495	152	53.42	8	152	2	145	3.0e-45	174	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
647045496	337	50.3	1	336	2	338	6.0e-97	347	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
647045497	788	40.98	8	788	2	766	0.0e+00	685	COG4775	Outer membrane protein assembly factor BamA	766
647045500	396	52.84	7	393	2	384	0.0e+00	487	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
647045501	275	33.46	1	263	1	254	1.0e-33	136	COG0575	CDP-diglyceride synthetase	265
647045502	253	53.91	8	237	14	243	9.0e-82	296	COG0020	Undecaprenyl pyrophosphate synthase	245
647045503	185	58.38	1	185	3	187	6.0e-65	240	COG0233	Ribosome recycling factor	187
647045504	240	62.39	6	238	5	238	4.0e-88	317	COG0528	Uridylate kinase	238
647045507	292	55.41	1	290	2	295	3.0e-83	301	COG0264	Translation elongation factor EF-Ts	296
647045508	267	54.55	1	250	1	252	8.0e-97	346	COG0052	Ribosomal protein S2	252
647045509	239	25.22	10	230	7	224	9.0e-20	90.5	COG3121	P pilus assembly protein, chaperone PapD	235
647045511	344	40.12	174	344	4	174	4.0e-18	85.8	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
647045512	783	25.68	26	777	55	835	6.0e-93	335	COG3188	Outer membrane usher protein FimD/PapC	835
647045513	260	24.53	24	231	9	211	1.0e-26	113	COG3121	P pilus assembly protein, chaperone PapD	235
647045516	258	55.34	1	251	1	252	2.0e-97	349	COG0024	Methionine aminopeptidase	255
647045517	869	43.42	36	869	29	864	0.0e+00	655	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
647045518	401	49.82	133	399	8	271	2.0e-80	292	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
647045520	118	37.07	1	115	2	115	5.0e-27	112	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
647045522	376	38.13	1	374	12	407	7.0e-79	287	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647045524	495	34.39	1	493	67	542	9.0e-101	360	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
647045526	712	23.71	5	712	21	719	6.0e-56	212	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
647045528	805	26.21	3	804	1	767	2.0e-62	234	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
647045529	161	50.32	1	156	1	156	4.0e-42	163	COG2193	Bacterioferritin (cytochrome b1)	157
647045530	133	31.87	2	92	1	91	8.0e-12	62.8	COG3293	Transposase	124
647045531	464	46.14	1	464	1	457	0.0e+00	488	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
647045532	537	27.22	208	528	8	327	4.0e-30	126	COG0642	Signal transduction histidine kinase	336
647045533	389	57.95	1	388	1	387	0.0e+00	498	COG0045	Succinyl-CoA synthetase, beta subunit	387
647045534	291	69.52	1	291	1	290	2.0e-118	418	COG0074	Succinyl-CoA synthetase, alpha subunit	293
647045537	538	40.79	261	525	8	268	2.0e-69	257	COG0171	NH3-dependent NAD+ synthetase	268
647045538	293	37.84	13	271	6	253	6.0e-64	237	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
647045539	331	48.15	17	308	5	288	7.0e-80	290	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
647045543	747	42.78	10	743	6	742	0.0e+00	765	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
647045544	283	41.51	163	267	13	118	2.0e-19	89.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647045545	146	30.89	17	139	1	122	2.0e-08	51.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
647045546	505	37.39	44	495	6	456	2.0e-58	220	COG1538	Outer membrane protein TolC	457
647045547	397	43.32	14	349	7	343	3.0e-79	289	COG1566	Multidrug resistance efflux pump	352
647045554	714	34.99	24	703	5	686	0.0e+00	516	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
647045557	729	31.53	68	390	46	367	1.0e-56	214	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
647045559	521	24.36	16	514	20	493	8.0e-56	211	COG3104	Dipeptide/tripeptide permease	498
647045560	202	29	1	193	25	218	2.0e-13	69	COG0705	Membrane associated serine protease, rhomboid family	228
647045562	104	37.76	10	104	1	98	7.0e-19	85.4	COG2388	Predicted acetyltransferase, GNAT superfamily	99
647045564	166	37.07	45	159	13	126	6.0e-14	70.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
647045572	724	44.27	32	715	2	681	0.0e+00	738	COG0339	Zn-dependent oligopeptidase	683
647045573	161	53.46	1	159	2	160	2.0e-70	257	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
647045574	259	33.83	1	256	1	266	2.0e-49	188	COG1018	Ferredoxin-NADP reductase	266
647045575	683	30.54	87	681	1	567	2.0e-87	317	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647045576	505	50	1	303	2	297	1.0e-109	390	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
647045577	211	33.83	3	200	2	200	4.0e-26	111	COG0625	Glutathione S-transferase	211
647045578	400	40.56	151	396	74	313	2.0e-59	223	COG2829	Outer membrane phospholipase A	317
647045579	161	37.18	4	157	2	156	4.0e-17	81	COG2839	Uncharacterized conserved protein YqgC, DUF456 family	160
647045580	71	56.72	6	71	1	67	3.0e-20	90.2	COG1278	Cold shock protein, CspA family	67
647045581	160	23.46	1	160	1	151	3.0e-06	44.9	COG3133	Outer membrane lipoprotein SlyB	154
647045583	276	50.97	5	263	9	260	4.0e-87	314	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
647045584	255	42.97	1	253	1	256	3.0e-74	272	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
647045586	263	35	3	201	2	167	6.0e-40	157	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
647045587	391	36.6	19	391	5	392	1.0e-69	257	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647045588	209	37.56	5	203	1	203	5.0e-32	131	COG0625	Glutathione S-transferase	211
647045590	646	31.47	1	621	1	530	1.0e-94	341	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
647045591	184	36.87	4	175	1	175	2.0e-33	135	COG0431	NAD(P)H-dependent FMN reductase	184
647045592	476	55.81	31	469	1	435	0.0e+00	559	COG0305	Replicative DNA helicase	435
647045593	484	42.11	13	483	1	461	1.0e-121	430	COG0415	Deoxyribodipyrimidine photolyase	461
647045594	241	46.35	37	228	4	189	9.0e-39	153	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
647045595	344	36	3	297	1	291	1.0e-39	157	COG0583	DNA-binding transcriptional regulator, LysR family	297
647045598	241	22.35	1	178	3	178	1.0e-08	53.3	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647045599	396	31.97	8	369	6	357	4.0e-33	136	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
647045600	1058	46.63	2	1037	1	1009	0.0e+00	996	COG0841	Multidrug efflux pump subunit AcrB	1009
647045601	243	35.53	1	224	2	214	5.0e-34	138	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647045602	474	35.89	12	467	1	453	6.0e-55	208	COG1538	Outer membrane protein TolC	457
647045603	324	42.86	153	323	7	181	1.0e-36	147	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
647045606	551	42.46	365	542	3	179	2.0e-39	157	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
647045609	270	30.92	14	262	2	230	5.0e-16	78.5	COG2801	Transposase InsO and inactivated derivatives	232
647045614	372	22.08	57	355	1	303	4.0e-10	59.6	COG0582	Integrase	309
647045617	167	53.95	14	165	3	153	5.0e-51	193	COG0691	tmRNA-binding protein	153
647045618	143	46.81	1	140	1	141	3.0e-42	164	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
647045619	91	38.71	1	88	4	96	3.0e-16	76.5	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
647045620	131	30.83	1	129	11	143	2.0e-21	94.3	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
647045621	136	49.19	6	129	12	133	8.0e-30	122	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
647045624	343	41.94	1	340	3	343	2.0e-91	329	COG1420	Transcriptional regulator of heat shock response	346
647045625	172	40.49	11	170	29	191	7.0e-37	146	COG0576	Molecular chaperone GrpE (heat shock protein)	193
647045626	641	60.17	1	599	4	572	0.0e+00	659	COG0443	Molecular chaperone DnaK (HSP70)	579
647045627	376	54.35	1	373	1	371	0.0e+00	461	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
647045628	302	36.65	24	302	2	281	2.0e-54	206	COG2240	Pyridoxal/pyridoxine/pyridoxamine kinase	281
647045629	373	30.43	5	258	4	268	1.0e-36	147	COG0287	Prephenate dehydrogenase	279
647045632	370	18.84	1	360	85	442	3.0e-12	66.3	COG1538	Outer membrane protein TolC	457
647045634	361	22.95	14	273	8	287	5.0e-15	75.8	COG1566	Multidrug resistance efflux pump	352
647045635	562	20.99	13	562	143	707	5.0e-40	159	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
647045636	299	33.45	7	299	2	292	1.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
647045637	589	40.73	15	586	1	565	4.0e-130	458	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647045638	212	31.84	16	210	3	203	2.0e-44	172	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
647045640	197	35.75	1	189	14	205	8.0e-40	156	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
647045641	478	44.54	1	466	1	454	0.0e+00	479	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
647045642	403	48.06	1	400	1	402	4.0e-109	388	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
647045648	497	44.44	20	379	12	357	6.0e-94	338	COG2850	Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain	383
647045652	455	34.51	12	455	1	435	2.0e-104	373	COG0015	Adenylosuccinate lyase	438
647045654	440	38.71	5	438	4	428	6.0e-94	338	COG1253	Hemolysin or related protein, contains CBS domains	429
647045655	467	55.41	3	458	1	462	0.0e+00	649	COG0114	Fumarate hydratase class II	462
647045660	291	30	9	288	4	293	1.0e-45	177	COG1131	ABC-type multidrug transport system, ATPase component	293
647045661	120	40.18	4	115	4	114	6.0e-23	99.5	COG1725	DNA-binding transcriptional regulator YhcF, GntR family	125
647045664	185	50	24	180	3	160	5.0e-56	210	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
647045665	353	42.11	147	352	3	205	6.0e-51	194	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
647045666	449	57.34	1	429	1	414	0.0e+00	594	COG1004	UDP-glucose 6-dehydrogenase	414
647045667	78	47.14	9	78	3	72	4.0e-12	63	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
647045668	250	29.1	12	250	5	215	1.0e-35	143	COG3122	Uncharacterized conserved protein YaiL, DUF2058 family	215
647045670	389	37.46	36	363	1	330	4.0e-70	258	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
647045671	438	50	19	436	10	421	1.0e-105	377	COG0738	Fucose permease	422
647045672	328	38.18	8	328	2	311	2.0e-51	196	COG0524	Sugar or nucleoside kinase, ribokinase family	311
647045673	401	38.69	6	401	1	387	1.0e-107	383	COG2942	Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family	388
647045674	917	55.75	3	880	9	840	0.0e+00	1088	COG1410	Methionine synthase I, cobalamin-binding domain	842
647045675	379	55.65	23	364	3	310	8.0e-110	390	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
647045677	382	46.02	1	381	1	389	5.0e-90	324	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647045679	465	22.33	29	226	10	216	3.0e-10	60.3	COG2755	Lysophospholipase L1 or related esterase	216
647045681	849	45.56	122	824	1	706	0.0e+00	698	COG0557	Exoribonuclease R	706
647045683	157	43.18	4	132	1	132	2.0e-32	131	COG3791	Uncharacterized conserved protein	133
647045684	249	42.56	7	247	23	258	8.0e-57	213	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
647045685	1011	24.06	37	679	8	651	7.0e-57	216	COG3292	Periplasmic ligand-binding sensor domain	671
647045686	211	29.02	14	200	1	175	2.0e-20	92.2	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
647045687	126	35.48	37	126	37	129	2.0e-09	54.6	COG5455	Periplasmic regulator RcnB of Ni and Co efflux	129
647045688	236	38.66	1	236	1	238	5.0e-41	161	COG0704	Phosphate uptake regulator	240
647045689	276	62.6	23	276	1	253	2.0e-119	421	COG1117	ABC-type phosphate transport system, ATPase component	253
647045690	289	45.64	3	283	1	287	4.0e-69	254	COG0581	ABC-type phosphate transport system, permease component	292
647045691	324	47.04	8	322	2	310	5.0e-76	277	COG0573	ABC-type phosphate transport system, permease component	310
647045692	363	36.87	1	351	1	318	3.0e-59	222	COG0226	ABC-type phosphate transport system, periplasmic component	318
647045693	339	38.51	12	326	30	318	2.0e-59	223	COG0226	ABC-type phosphate transport system, periplasmic component	318
647045694	416	28.18	3	414	12	424	2.0e-40	160	COG3746	Phosphate-selective porin	426
647045697	226	41.75	1	203	4	205	7.0e-51	194	COG0288	Carbonic anhydrase	207
647045698	527	29.75	1	498	2	512	7.0e-77	281	COG0659	Sulfate permease or related transporter, MFS superfamily	554
647045699	236	57.89	16	224	1	209	1.0e-83	302	COG0177	Endonuclease III	211
647045701	260	50.97	1	255	2	256	6.0e-52	197	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647045702	232	36.11	19	232	1	205	5.0e-33	134	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
647045705	266	41.2	1	266	3	260	1.0e-53	203	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
647045706	317	29.23	35	315	2	261	5.0e-34	138	COG3358	Uncharacterized conserved protein, DUF1684 family	262
647045708	163	31.65	15	163	11	160	7.0e-20	90	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
647045709	175	18.99	21	172	49	204	7.0e-06	43.8	COG2945	Alpha/beta superfamily hydrolase	210
647045710	168	41.04	1	166	2	169	6.0e-27	113	COG3153	Predicted N-acetyltransferase YhbS	171
647045711	536	33.27	4	518	2	502	2.0e-87	316	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
647045716	240	30	9	238	47	275	1.0e-50	193	COG0061	NAD kinase	281
647045720	330	31.03	10	323	2	310	2.0e-47	182	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
647045721	214	45.58	2	214	18	228	5.0e-64	237	COG5587	Uncharacterized conserved protein, DUF2461 family	228
647045723	481	47.8	1	477	7	474	0.0e+00	590	COG2925	Exonuclease I	475
647045724	445	27.67	2	360	8	353	6.0e-30	125	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647045725	423	37.65	5	419	5	398	5.0e-92	331	COG3844	Kynureninase	407
647045726	709	22.19	15	606	11	596	7.0e-23	102	COG1289	Uncharacterized membrane protein YccC	674
647045730	212	36.84	1	203	1	207	1.0e-34	139	COG2808	Predicted FMN-binding regulatory protein PaiB	209
647045734	464	46.04	13	464	12	435	0.0e+00	531	COG0017	Aspartyl/asparaginyl-tRNA synthetase	435
647045736	112	47.22	1	107	3	110	6.0e-32	129	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
647045737	143	46.43	3	113	1	112	1.0e-31	129	COG0360	Ribosomal protein S6	112
647045738	76	58.82	1	68	8	75	1.0e-21	94.5	COG0238	Ribosomal protein S18	75
647045739	149	46.98	1	149	1	148	7.0e-40	156	COG0359	Ribosomal protein L9	148
647045740	1167	34.35	1	1164	1	1163	0.0e+00	659	COG1196	Chromosome segregation ATPase	1163
647045744	374	30.4	35	374	7	353	3.0e-52	199	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
647045745	833	46.77	1	650	1	582	0.0e+00	741	COG0272	NAD-dependent DNA ligase	667
647045746	320	48.42	6	320	11	322	1.0e-101	363	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
647045749	354	53.62	13	353	1	345	2.0e-124	439	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
647045750	899	55.29	1	876	1	803	0.0e+00	1029	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
647045754	558	74.73	1	554	3	556	0.0e+00	960	COG2987	Urocanate hydratase	561
647045755	311	47.23	32	302	7	272	5.0e-83	301	COG3741	N-formylglutamate amidohydrolase	272
647045756	501	63.99	2	486	13	496	0.0e+00	609	COG2986	Histidine ammonia-lyase	498
647045757	401	41.58	1	398	1	397	8.0e-94	337	COG1228	Imidazolonepropionase or related amidohydrolase	406
647045758	451	25.39	1	438	3	420	3.0e-54	206	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
647045759	140	22.41	22	133	3	117	4.0e-06	43.7	COG2346	Truncated hemoglobin YjbI	133
647045761	349	47.43	84	336	1	252	6.0e-70	257	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
647045764	312	36.74	1	304	2	306	5.0e-68	251	COG3491	Isopenicillin N synthase and related dioxygenases	322
647045765	449	43.94	1	449	4	461	3.0e-112	398	COG1109	Phosphomannomutase	464
647045766	295	60.68	1	295	1	293	4.0e-119	421	COG0777	Acetyl-CoA carboxylase beta subunit	294
647045768	274	45.28	9	273	3	265	1.0e-75	276	COG0159	Tryptophan synthase alpha chain	265
647045770	405	66.33	11	402	1	391	0.0e+00	665	COG0133	Tryptophan synthase beta chain	396
647045771	308	28.19	6	297	1	295	3.0e-24	105	COG0583	DNA-binding transcriptional regulator, LysR family	297
647045772	222	41.4	7	216	1	208	6.0e-57	213	COG0135	Phosphoribosylanthranilate isomerase	208
647045773	257	46.83	1	252	2	251	3.0e-82	298	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
647045774	135	36.67	17	127	5	124	2.0e-15	75.3	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
647045775	642	24.3	7	642	29	755	6.0e-38	152	COG3170	Tfp pilus assembly protein FimV	755
647045777	341	56.97	8	338	2	334	1.0e-120	426	COG0136	Aspartate-semialdehyde dehydrogenase	334
647045779	286	44.84	6	284	2	279	3.0e-76	278	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
647045780	367	55.62	2	359	1	364	0.0e+00	501	COG0082	Chorismate synthase	369
647045781	308	39.04	10	297	1	279	4.0e-53	201	COG2890	Methylase of polypeptide chain release factors	280
647045782	216	33.01	8	212	8	205	3.0e-33	135	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
647045783	282	31.25	7	276	2	239	5.0e-45	174	COG0688	Phosphatidylserine decarboxylase	239
647045786	501	30.89	23	423	8	444	7.0e-29	122	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
647045790	167	45.39	15	166	1	151	7.0e-35	140	COG0782	Transcription elongation factor, GreA/GreB family	151
647045792	454	36.73	5	441	2	437	2.0e-128	452	COG0621	tRNA A37 methylthiotransferase MiaB	437
647045793	220	32.63	1	220	1	235	7.0e-33	133	COG0412	Dienelactone hydrolase	236
647045794	144	21.97	13	138	5	135	2.0e-10	58.9	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
647045797	189	39.58	3	189	2	181	3.0e-58	218	COG0717	Deoxycytidine triphosphate deaminase	183
647045798	283	49.78	20	238	54	265	3.0e-56	212	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
647045802	700	46.17	53	700	9	654	0.0e+00	762	COG3590	Predicted metalloendopeptidase	654
647045803	699	43.95	49	699	9	654	0.0e+00	649	COG3590	Predicted metalloendopeptidase	654
647045804	671	30.2	44	670	21	654	8.0e-104	371	COG3590	Predicted metalloendopeptidase	654
647045806	232	34.98	2	224	14	228	2.0e-25	109	COG0705	Membrane associated serine protease, rhomboid family	228
647045807	135	49.43	34	118	10	94	1.0e-16	79.2	COG3695	Alkylated DNA nucleotide flippase Atl1, participates in nucleotide excision repair, Ada-like DNA-binding domain	103
647045808	456	35.75	6	455	4	453	2.0e-105	376	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
647045809	416	29.79	7	416	6	382	9.0e-41	161	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647045810	414	40	5	406	2	388	2.0e-69	256	COG2311	Uncharacterized membrane protein YeiB	394
647045811	159	47.83	1	159	1	161	1.0e-37	149	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
647045812	217	40	73	213	53	197	2.0e-26	112	COG0791	Cell wall-associated hydrolase, NlpC family	197
647045813	249	33.33	69	246	18	197	8.0e-24	104	COG0791	Cell wall-associated hydrolase, NlpC family	197
647045814	163	37.16	1	148	7	153	2.0e-34	138	COG1607	Acyl-CoA hydrolase	157
647045816	446	38.8	7	418	3	399	8.0e-83	301	COG1301	Na+/H+-dicarboxylate symporter	415
647045817	568	34.02	12	535	2	478	1.0e-100	360	COG1785	Alkaline phosphatase	482
647045818	469	38.43	52	260	24	236	9.0e-40	158	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
647045819	86	39.74	4	81	1	78	7.0e-10	55.3	COG1722	Exonuclease VII small subunit	81
647045820	291	42.64	1	261	2	257	6.0e-62	231	COG0142	Geranylgeranyl pyrophosphate synthase	322
647045822	128	35.92	11	128	5	143	1.0e-17	81.9	COG3296	Uncharacterized conserved protein, Tic20 family	143
647045824	455	38.77	23	453	3	453	7.0e-88	318	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
647045825	193	46.55	1	174	14	184	5.0e-44	170	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
647045826	481	44.59	23	479	4	454	1.0e-124	440	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
647045828	1306	29.35	10	1286	3	1268	0.0e+00	766	COG3164	Uncharacterized conserved protein YhdP, contains DUF3971 and AsmA2 domains	1271
647045830	499	47.2	2	499	1	483	0.0e+00	478	COG1530	Ribonuclease G or E	487
647045831	190	48.15	1	189	4	189	9.0e-56	209	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
647045832	244	44.44	2	244	1	243	5.0e-54	204	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
647045834	274	26.55	98	274	72	244	7.0e-13	67.9	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
647045835	156	47.74	1	155	1	155	6.0e-56	210	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
647045839	137	49.12	17	130	1	114	2.0e-33	134	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
647045840	190	33.15	3	185	37	197	9.0e-31	126	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
647045842	342	32.05	3	336	1	334	2.0e-54	206	COG1466	DNA polymerase III, delta subunit	334
647045843	214	30.39	1	181	1	176	1.0e-34	140	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
647045846	764	50.54	30	764	5	679	0.0e+00	892	COG0495	Leucyl-tRNA synthetase	814
647045848	285	42.51	1	285	19	304	1.0e-65	243	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
647045853	89	53.12	8	71	1	63	2.0e-16	77.5	COG2155	Uncharacterized membrane protein YuzA, DUF378 family	79
647045854	328	25.63	73	269	1	157	3.0e-15	76.4	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
647045863	151	23.21	38	148	6	112	8.0e-09	53.5	COG3791	Uncharacterized conserved protein	133
647045865	601	22.74	28	587	8	574	2.0e-29	124	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
647045867	610	32.71	22	604	1	567	5.0e-111	395	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647045870	1019	30.46	2	1013	1	1009	0.0e+00	667	COG0841	Multidrug efflux pump subunit AcrB	1009
647045871	367	24.79	8	352	15	365	7.0e-11	61.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
647045872	278	23.29	48	265	34	245	2.0e-19	89.6	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
647045873	487	32.24	57	480	20	444	5.0e-41	162	COG1538	Outer membrane protein TolC	457
647045874	229	42.24	4	229	1	226	1.0e-48	186	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647045875	397	30.62	80	397	20	331	5.0e-39	155	COG0642	Signal transduction histidine kinase	336
647045876	421	27.99	6	418	3	397	8.0e-40	158	COG0475	Kef-type K+ transport system, membrane component KefB	397
647045877	529	27	9	363	16	363	3.0e-41	163	COG1680	CubicO group peptidase, beta-lactamase class C family	390
647045878	166	44.44	5	160	13	174	6.0e-40	156	COG0684	Regulator of RNase E activity RraA	210
647045880	324	29.37	60	321	1	246	2.0e-41	162	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
647045881	315	24.19	2	269	1	262	1.0e-05	44.4	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
647045882	240	38.62	4	234	4	242	9.0e-51	193	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
647045884	640	42.65	1	470	21	508	5.0e-125	441	COG0513	Superfamily II DNA and RNA helicase	513
647045887	80	41.43	5	74	4	73	1.0e-13	67.9	COG2501	Ribosome-associated protein YbcJ, S4-like RNA binding protein	73
647045889	133	38.71	7	130	1	123	5.0e-18	83.4	COG3686	Uncharacterized conserved protein, MAPEG superfamily	125
647045894	487	38.33	210	487	5	281	3.0e-44	173	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
647045895	181	38.69	3	160	1	168	1.0e-41	162	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
647045896	432	25.47	19	414	12	439	5.0e-57	215	COG1524	Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily	450
647045897	476	32.95	39	460	5	432	1.0e-47	184	COG0038	H+/Cl- antiporter ClcA	443
647045898	346	38.33	1	346	4	338	6.0e-86	311	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
647045902	551	19.89	20	551	122	608	2.0e-26	113	COG4206	Outer membrane cobalamin receptor protein	608
647045903	793	18.66	4	793	15	768	2.0e-23	105	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647045909	343	44.38	1	325	1	314	6.0e-81	294	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
647045916	447	29.92	170	296	1	127	7.0e-20	92.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647045921	429	30.81	1	393	9	394	3.0e-67	249	COG0019	Diaminopimelate decarboxylase	394
647045922	589	25.63	24	578	27	597	4.0e-62	232	COG4264	Siderophore synthetase component	602
647045924	600	25.97	1	482	14	502	1.0e-35	145	COG4264	Siderophore synthetase component	602
647045927	713	31.62	18	713	9	753	3.0e-120	426	COG4772	Outer membrane receptor for Fe3+-dicitrate	753
647045928	253	33.19	5	240	19	253	1.0e-39	156	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
647045929	565	72.51	1	411	1	405	0.0e+00	502	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
647045933	799	21.14	2	799	3	699	2.0e-37	151	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
647045935	795	20.38	1	771	1	684	3.0e-33	137	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
647045938	795	23.53	3	768	5	679	2.0e-40	161	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
647045940	638	44.1	1	542	3	530	0.0e+00	525	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
647045941	291	32.07	6	286	1	290	4.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
647045942	297	33.77	10	297	22	326	1.0e-37	150	COG2367	Beta-lactamase class A	329
647045945	718	40.35	1	552	1	523	1.0e-120	427	COG3511	Phospholipase C	527
647045949	274	23.5	64	263	41	226	3.0e-10	59.2	COG2801	Transposase InsO and inactivated derivatives	232
647045954	340	31.31	5	326	1	301	8.0e-30	124	COG0524	Sugar or nucleoside kinase, ribokinase family	311
647045956	402	65.84	1	401	1	398	0.0e+00	631	COG3007	Trans-2-enoyl-CoA reductase	398
647045960	178	30.37	46	178	15	149	4.0e-23	100	COG4704	Uncharacterized conserved protein, DUF2141 family	151
647045961	505	34.96	47	505	22	488	2.0e-87	316	COG3670	Carotenoid cleavage dioxygenase or a related enzyme	490
647045962	388	47.34	8	382	3	355	4.0e-104	371	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
647045963	318	38.03	1	284	2	278	5.0e-63	234	COG1273	Non-homologous end joining protein Ku, dsDNA break repair	278
647045967	712	21.38	4	710	14	753	1.0e-38	155	COG4772	Outer membrane receptor for Fe3+-dicitrate	753
647045968	400	59.45	3	398	1	396	0.0e+00	572	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
647045971	270	25	7	249	14	242	2.0e-24	106	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647045972	722	30.65	98	421	12	334	5.0e-39	156	COG0642	Signal transduction histidine kinase	336
647045973	380	47.85	28	371	15	360	7.0e-106	377	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
647045974	505	59.36	9	505	5	502	0.0e+00	715	COG1190	Lysyl-tRNA synthetase (class II)	502
647045975	276	63.18	30	267	1	239	7.0e-97	347	COG1186	Protein chain release factor B	239
647045982	579	39.33	48	552	13	491	4.0e-97	349	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
647045983	306	32.59	13	305	2	316	2.0e-64	239	COG4255	Uncharacterized protein	318
647045984	154	49.34	1	152	1	150	2.0e-37	148	COG0782	Transcription elongation factor, GreA/GreB family	151
647045988	377	59.68	4	374	3	366	0.0e+00	566	COG0505	Carbamoylphosphate synthase small subunit	368
647045989	238	42.97	4	236	1	263	3.0e-65	241	COG0289	Dihydrodipicolinate reductase	266
647045991	239	49.77	14	225	1	210	3.0e-62	231	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
647045992	420	45.16	17	414	57	459	3.0e-102	365	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
647045996	82	35.44	1	79	1	75	1.0e-10	57.9	COG1918	Fe2+ transport system protein FeoA	75
647045997	276	36.96	11	266	1	254	1.0e-35	143	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647045998	129	23.4	4	125	3	138	6.0e-07	46.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
647046000	256	37.35	8	252	8	251	4.0e-32	131	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647046001	188	30.53	1	131	4	131	1.0e-25	109	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
647046005	472	40.78	8	460	1	456	2.0e-90	326	COG0277	FAD/FMN-containing dehydrogenase	459
647046006	413	42.77	10	338	1	324	1.0e-84	307	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
647046008	490	32.18	42	490	20	460	6.0e-45	175	COG0531	Amino acid transporter	466
647046009	471	33.76	22	471	9	455	5.0e-43	169	COG0531	Amino acid transporter	466
647046010	217	33.99	15	213	5	194	8.0e-32	130	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
647046011	188	52.46	1	182	1	177	8.0e-61	226	COG1791	Acireductone dioxygenase (methionine salvage), cupin superfamily	181
647046012	232	50.65	1	231	1	227	1.0e-83	302	COG4229	Enolase-phosphatase E1 involved in merthionine salvage	229
647046014	528	20.9	193	432	60	289	4.0e-06	46.5	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
647046015	206	53.33	10	113	6	109	3.0e-37	148	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
647046016	258	52.71	1	255	1	254	8.0e-100	356	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
647046017	244	45.68	3	244	2	237	2.0e-65	241	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
647046018	200	48.28	1	197	1	202	5.0e-66	243	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
647046019	375	56.87	167	375	2	195	1.0e-80	293	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
647046020	363	43.61	9	357	1	350	4.0e-76	278	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
647046021	431	52.59	6	427	1	421	0.0e+00	498	COG0141	Histidinol dehydrogenase	425
647046022	304	38.98	11	303	1	289	7.0e-76	277	COG0040	ATP phosphoribosyltransferase	290
647046023	90	37.93	2	88	14	100	2.0e-21	93.8	COG4496	Uncharacterized protein YerC	100
647046024	468	35.45	1	454	11	429	6.0e-106	378	COG0124	Histidyl-tRNA synthetase	429
647046025	253	29.27	40	241	9	213	1.0e-30	126	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
647046027	434	34.38	1	403	2	391	9.0e-74	271	COG0498	Threonine synthase	411
647046029	337	35.92	32	337	1	298	3.0e-61	228	COG0083	Homoserine kinase	299
647046030	829	40.91	13	471	2	447	1.0e-113	405	COG0527	Aspartokinase	447
647046032	166	38.78	23	164	14	160	1.0e-21	96.1	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
647046043	635	27.95	190	591	134	492	2.0e-14	74.6	COG1404	Serine protease, subtilisin family	508
647046047	253	21.37	14	245	45	278	2.0e-07	49.9	COG0842	ABC-type multidrug transport system, permease component	286
647046048	314	36.57	1	306	1	293	4.0e-74	271	COG1131	ABC-type multidrug transport system, ATPase component	293
647046049	545	39.37	1	443	6	429	7.0e-72	265	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
647046052	705	64.83	1	704	1	690	0.0e+00	998	COG0480	Translation elongation factor EF-G, a GTPase	697
647046054	155	58.78	2	148	1	148	3.0e-50	190	COG0049	Ribosomal protein S7	148
647046055	124	74.8	1	123	7	129	8.0e-47	178	COG0048	Ribosomal protein S12	129
647046056	1405	52.09	20	852	7	806	0.0e+00	914	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
647046058	121	65.32	1	121	1	124	6.0e-23	99.5	COG0222	Ribosomal protein L7/L12	124
647046059	177	43.27	1	170	1	171	2.0e-31	128	COG0244	Ribosomal protein L10	175
647046060	232	57.33	4	227	5	228	4.0e-71	261	COG0081	Ribosomal protein L1	228
647046061	142	67.38	2	142	1	140	4.0e-49	186	COG0080	Ribosomal protein L11	141
647046063	185	50.54	1	184	2	176	5.0e-51	193	COG0250	Transcription antitermination factor NusG	178
647046064	136	45.21	60	132	1	73	5.0e-10	56.9	COG0690	Preprotein translocase subunit SecE	73
647046066	396	82.07	1	396	1	394	0.0e+00	707	COG0050	Translation elongation factor EF-Tu, a GTPase	394
647046070	363	61.29	1	363	1	372	0.0e+00	500	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
647046071	193	49.47	3	192	1	190	3.0e-67	248	COG0193	Peptidyl-tRNA hydrolase	190
647046072	210	47.87	4	97	1	93	3.0e-23	101	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
647046073	319	58.41	4	317	2	313	3.0e-114	404	COG0462	Phosphoribosylpyrophosphate synthetase	314
647046076	295	45.64	14	288	3	288	7.0e-79	287	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
647046077	217	31.34	1	215	3	205	6.0e-32	130	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
647046079	432	47.84	1	412	1	414	9.0e-121	427	COG0373	Glutamyl-tRNA reductase	414
647046080	361	62.91	1	360	1	363	0.0e+00	508	COG0216	Protein chain release factor A	363
647046081	568	33.88	25	558	71	613	6.0e-93	335	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
647046082	172	44.65	7	163	5	162	8.0e-48	183	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
647046083	260	57.89	2	229	43	270	4.0e-86	311	COG2326	Polyphosphate kinase 2, PPK2 family	270
647046085	88	47.06	1	85	3	85	7.0e-18	82.2	COG1254	Acylphosphatase	92
647046086	203	24.78	70	181	13	125	7.0e-10	57.6	COG0526	Thiol-disulfide isomerase or thioredoxin	127
647046087	425	30.36	13	282	9	288	2.0e-37	150	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
647046088	198	33.98	1	195	3	205	2.0e-32	132	COG0655	Multimeric flavodoxin WrbA	207
647046092	157	40.26	5	153	2	154	1.0e-28	119	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
647046094	565	33.67	148	524	128	485	9.0e-18	85.4	COG1404	Serine protease, subtilisin family	508
647046097	553	32.35	131	524	128	502	1.0e-14	75.4	COG1404	Serine protease, subtilisin family	508
647046098	361	38.96	44	350	2	284	1.0e-64	240	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
647046099	184	41.12	77	183	8	110	2.0e-26	112	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
647046103	187	31.14	21	185	16	177	5.0e-19	87.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
647046109	191	26.18	7	181	6	195	1.0e-11	63.4	COG0778	Nitroreductase	207
647046110	328	32.54	19	305	11	297	7.0e-47	181	COG0258	5'-3' exonuclease	310
647046112	261	44.4	9	258	4	253	6.0e-73	267	COG3931	Predicted N-formylglutamate amidohydrolase	263
647046113	313	25.17	20	313	8	279	5.0e-18	85.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647046117	281	46.62	16	280	15	278	3.0e-65	241	COG2890	Methylase of polypeptide chain release factors	280
647046119	187	51.06	1	184	2	188	6.0e-64	236	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
647046120	530	73.51	1	520	1	520	0.0e+00	861	COG3634	Alkyl hydroperoxide reductase subunit AhpF	520
647046121	313	37.63	1	293	1	289	2.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
647046123	322	34.39	8	317	1	238	1.0e-52	200	COG0176	Transaldolase	239
647046124	189	27.32	1	169	2	182	7.0e-07	47.5	COG0693	Putative intracellular protease/amidase	188
647046125	216	52.02	43	215	4	173	8.0e-63	233	COG0225	Peptide methionine sulfoxide reductase MsrA	174
647046127	171	55	3	162	2	156	5.0e-44	170	COG4875	Uncharacterized protein	156
647046129	636	35.38	154	493	6	328	2.0e-39	157	COG0642	Signal transduction histidine kinase	336
647046133	247	27.23	40	245	1	211	4.0e-15	75.2	COG0625	Glutathione S-transferase	211
647046135	579	30.57	27	556	1	472	3.0e-90	326	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
647046140	186	30.72	26	178	7	149	5.0e-16	77.7	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
647046141	347	48.31	1	346	1	354	1.0e-129	455	COG2933	23S rRNA C2498 (ribose-2'-O)-methylase RlmM	358
647046142	369	27.49	35	363	1	335	1.0e-46	180	COG0673	Predicted dehydrogenase	342
647046143	301	30.59	43	280	27	273	3.0e-30	125	COG3386	Sugar lactone lactonase YvrE	307
647046146	157	29.17	16	134	1	120	1.0e-06	46.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
647046147	275	35.77	1	259	1	254	4.0e-51	194	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
647046148	492	33.46	1	491	10	528	7.0e-104	371	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647046153	469	28.8	150	459	2	294	4.0e-39	156	COG4313	Uncharacterized conserved protein	304
647046155	393	38.62	6	391	2	384	1.0e-62	233	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647046156	402	36.39	3	392	1	387	2.0e-60	226	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647046158	185	50.27	2	184	1	184	3.0e-54	204	COG2096	Cob(I)alamin adenosyltransferase	184
647046159	302	42.39	1	301	4	309	4.0e-75	274	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
647046160	798	32.27	4	785	11	784	0.0e+00	473	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
647046161	463	17.25	9	313	3	298	1.0e-12	68.2	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
647046162	323	50.15	1	323	1	329	2.0e-103	368	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
647046164	262	50.2	7	258	2	252	2.0e-80	292	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
647046165	127	53.17	2	127	1	126	1.0e-45	175	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
647046167	164	43.79	2	164	1	167	2.0e-35	141	COG0262	Dihydrofolate reductase	167
647046168	264	71.43	1	264	3	268	7.0e-119	420	COG0207	Thymidylate synthase	268
647046169	296	39.8	1	290	5	287	2.0e-62	232	COG0682	Prolipoprotein diacylglyceryltransferase	287
647046171	288	40.14	1	288	4	271	7.0e-45	174	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
647046173	208	47.37	1	190	1	185	5.0e-58	217	COG1704	Uncharacterized conserved protein	185
647046174	126	47.5	7	126	3	122	4.0e-31	126	COG0818	Diacylglycerol kinase	123
647046175	233	19.79	55	233	24	211	9.0e-10	57.2	COG2755	Lysophospholipase L1 or related esterase	216
647046177	423	28.27	94	422	4	327	8.0e-37	148	COG0642	Signal transduction histidine kinase	336
647046178	237	45.58	11	231	3	227	7.0e-54	204	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647046179	217	33.18	29	216	3	213	4.0e-17	81.5	COG2755	Lysophospholipase L1 or related esterase	216
647046180	199	65.98	1	191	31	224	2.0e-67	248	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
647046183	305	47.7	25	305	5	282	6.0e-68	251	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
647046184	348	23.63	11	348	2	330	2.0e-25	110	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
647046185	277	46.46	3	256	1	248	4.0e-74	271	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
647046186	294	34.51	40	293	8	258	3.0e-41	162	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
647046187	117	62.93	2	117	1	116	2.0e-38	150	COG3169	Uncharacterized conserved protein, DUF486 family	116
647046190	743	24.54	2	726	3	687	8.0e-57	215	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
647046193	322	42.86	1	319	1	306	6.0e-75	274	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
647046195	432	44.63	10	428	5	402	2.0e-106	379	COG1972	Nucleoside permease NupC	404
647046196	316	32.41	3	316	1	304	5.0e-34	138	COG0524	Sugar or nucleoside kinase, ribokinase family	311
647046200	332	45.82	1	320	2	321	4.0e-94	338	COG0042	tRNA-dihydrouridine synthase	323
647046202	366	23.35	1	188	1	190	3.0e-08	53.5	COG1988	Membrane-bound metal-dependent hydrolase YbcI, DUF457 family	190
647046204	403	64.2	1	402	2	388	0.0e+00	653	COG0192	S-adenosylmethionine synthetase	388
647046207	923	14.72	147	923	26	768	7.0e-15	76.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647046211	904	41.02	14	904	6	910	0.0e+00	724	COG2352	Phosphoenolpyruvate carboxylase	910
647046212	823	21.1	229	813	31	620	2.0e-49	191	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
647046213	480	53.98	9	472	1	420	0.0e+00	627	COG0499	S-adenosylhomocysteine hydrolase	420
647046221	181	39.23	5	181	45	215	4.0e-21	94.4	COG3122	Uncharacterized conserved protein YaiL, DUF2058 family	215
647046224	311	23.78	7	303	4	330	1.0e-22	100	COG0673	Predicted dehydrogenase	342
647046228	325	40.48	6	325	1	326	1.0e-66	247	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647046230	275	40.07	1	274	14	288	4.0e-73	268	COG0685	5,10-methylenetetrahydrofolate reductase	291
647046234	315	32.26	133	314	6	191	2.0e-35	143	COG0352	Thiamine monophosphate synthase	211
647046235	912	58.41	2	905	1	822	0.0e+00	1095	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
647046238	303	59.04	1	292	1	293	5.0e-125	440	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
647046239	414	53.8	8	336	6	333	5.0e-103	368	COG0206	Cell division GTPase FtsZ	338
647046240	411	50.97	8	411	6	418	0.0e+00	480	COG0849	Cell division ATPase FtsA	418
647046241	290	31.45	3	243	24	269	2.0e-42	165	COG1589	Cell division septal protein FtsQ	269
647046242	318	46.86	16	318	2	317	6.0e-81	294	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
647046243	477	51.29	9	469	1	455	0.0e+00	556	COG0773	UDP-N-acetylmuramate-alanine ligase	459
647046244	405	45.2	1	348	4	355	8.0e-91	327	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
647046245	456	42.51	15	382	11	381	5.0e-89	321	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
647046246	361	44.83	20	361	1	316	2.0e-54	206	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
647046247	503	41.48	1	495	1	451	6.0e-109	388	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
647046248	495	45.82	24	488	12	475	5.0e-123	435	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
647046249	622	36.65	2	557	1	597	1.0e-129	457	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
647046250	87	41.38	1	87	19	105	2.0e-21	93.8	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
647046251	352	51.14	18	317	7	313	3.0e-109	388	COG0275	16S rRNA C1402 N4-methylase RsmH	314
647046252	151	35.57	4	151	1	146	6.0e-36	143	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
647046253	255	41.57	1	243	1	254	7.0e-50	190	COG3332	Uncharacterized conserved protein, contains NRDE domain	270
647046258	275	54.31	5	271	5	268	2.0e-89	322	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
647046260	576	27.29	1	573	2	604	8.0e-91	328	COG3107	Outer membrane lipoprotein LpoA, binds and activates PBP1a	604
647046261	122	50.43	5	119	1	114	3.0e-27	113	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
647046262	179	38.57	23	158	29	166	6.0e-10	57.4	COG1988	Membrane-bound metal-dependent hydrolase YbcI, DUF457 family	190
647046263	461	42.17	13	461	2	459	9.0e-89	321	COG0277	FAD/FMN-containing dehydrogenase	459
647046264	238	42.67	12	233	2	225	2.0e-55	209	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647046265	886	42.82	2	874	1	879	0.0e+00	809	COG2205	K+-sensing histidine kinase KdpD	890
647046266	211	47.31	15	196	5	190	6.0e-49	187	COG2156	K+-transporting ATPase, c chain	190
647046267	682	62.43	15	679	5	678	0.0e+00	887	COG2216	High-affinity K+ transport system, ATPase chain B	681
647046268	597	43.59	1	594	5	560	0.0e+00	547	COG2060	K+-transporting ATPase, A chain	560
647046275	324	47.24	1	322	3	317	2.0e-86	313	COG0611	Thiamine monophosphate kinase	317
647046277	156	48.57	21	153	10	149	2.0e-35	141	COG0781	Transcription termination factor NusB	151
647046278	154	50.99	1	151	1	151	5.0e-46	176	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
647046279	379	60.29	1	204	1	203	6.0e-80	291	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
647046280	200	50.26	1	194	1	192	3.0e-67	248	COG0307	Riboflavin synthase alpha chain	204
647046282	369	68.06	9	152	3	146	2.0e-56	213	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
647046283	158	26.28	1	134	2	127	7.0e-06	43.3	COG3153	Predicted N-acetyltransferase YhbS	171
647046284	174	64	1	150	1	150	8.0e-55	206	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
647046285	417	67.4	8	417	7	413	0.0e+00	667	COG0112	Glycine/serine hydroxymethyltransferase	413
647046286	771	16.25	11	734	4	737	4.0e-19	90.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647046289	165	26.36	52	161	25	125	8.0e-06	43.4	COG5455	Periplasmic regulator RcnB of Ni and Co efflux	129
647046290	553	47.7	3	537	1	530	0.0e+00	564	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
647046291	171	42.41	1	158	2	154	1.0e-44	172	COG0242	Peptide deformylase	168
647046292	140	40.52	1	116	1	116	1.0e-32	132	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
647046297	392	40.15	1	388	9	378	3.0e-95	342	COG1488	Nicotinic acid phosphoribosyltransferase	405
647046301	635	24.56	209	601	4	396	2.0e-38	154	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
647046303	284	28.36	6	276	5	276	8.0e-42	164	COG1216	Glycosyltransferase, GT2 family	305
647046305	385	22.94	57	335	44	288	4.0e-13	69.2	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
647046306	720	22.85	12	720	20	719	7.0e-43	169	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
647046307	191	29.89	1	180	26	209	3.0e-22	98.4	COG3201	Nicotinamide riboside transporter PnuC	222
647046308	242	34.33	1	233	4	235	9.0e-47	180	COG2188	DNA-binding transcriptional regulator, GntR family	236
647046310	768	25.97	58	753	2	562	3.0e-85	310	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
647046313	358	25.53	179	358	6	191	5.0e-09	55.7	COG3166	Tfp pilus assembly protein PilN	206
647046314	283	29.68	5	283	6	313	1.0e-33	137	COG3156	Type II secretory pathway, component PulK	323
647046317	169	30	17	169	2	171	3.0e-20	91.6	COG4970	Tfp pilus assembly protein FimT	181
647046318	143	29.79	15	141	7	147	2.0e-10	58.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
647046319	405	40.49	1	405	1	397	9.0e-95	340	COG1459	Type II secretory pathway, component PulF	397
647046321	575	50.2	94	574	20	500	0.0e+00	518	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
647046326	1348	34.29	161	1024	11	733	0.0e+00	673	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
647046329	264	23.75	25	256	10	243	2.0e-22	99.5	COG1651	Protein-disulfide isomerase	244
647046330	323	53.31	23	323	5	300	5.0e-100	357	COG4974	Site-specific recombinase XerD	300
647046333	368	29.89	5	367	1	362	7.0e-56	211	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
647046334	360	35.62	1	352	1	363	8.0e-47	181	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
647046335	490	47.96	8	489	5	484	0.0e+00	500	COG0260	Leucyl aminopeptidase	485
647046338	141	34.93	1	141	1	141	6.0e-27	113	COG2927	DNA polymerase III, chi subunit	144
647046339	944	49.37	4	944	1	875	0.0e+00	1141	COG0525	Valyl-tRNA synthetase	877
647046346	105	25	3	102	2	105	1.0e-07	48.1	COG5611	Predicted nucleic-acid-binding protein, contains PIN domain	130
647046349	253	45.02	1	250	38	288	2.0e-42	165	COG0382	4-hydroxybenzoate polyprenyltransferase	289
647046364	86	40.24	1	82	1	82	2.0e-14	70.6	COG4794	Type III secretory pathway, component EscS	89
647046365	214	55.4	3	214	1	213	2.0e-69	255	COG4790	Type III secretory pathway, component EscR	214
647046369	628	46.38	1	628	15	688	0.0e+00	686	COG4789	Type III secretory pathway, component EscV	689
647046370	357	39.61	1	354	5	360	2.0e-91	329	COG1377	Flagellar biosynthesis protein FlhB	363
647046373	254	41.38	1	231	1	231	3.0e-62	232	COG4669	Type III secretory pathway, lipoprotein EscJ	246
647046375	233	27.89	46	226	44	231	4.0e-14	71.9	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
647046376	442	57.64	9	440	9	440	0.0e+00	586	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
647046378	276	35.68	10	250	1	240	8.0e-36	144	COG4791	Type III secretory pathway, component EscT	259
647046380	593	26.96	2	593	12	549	4.0e-70	259	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
647046387	804	28.14	14	803	50	832	4.0e-93	336	COG3264	Small-conductance mechanosensitive channel	835
647046388	702	20.04	3	485	137	593	4.0e-28	120	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
647046390	574	33.27	28	524	16	514	8.0e-89	321	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
647046391	313	53.29	1	308	1	303	1.0e-80	293	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
647046392	462	37.09	43	461	13	406	5.0e-93	335	COG1649	Uncharacterized lipoprotein YddW, UPF0748 family	418
647046396	743	54.57	116	741	1	628	0.0e+00	730	COG0296	1,4-alpha-glucan branching enzyme	628
647046397	585	30.91	11	581	26	627	7.0e-115	408	COG0296	1,4-alpha-glucan branching enzyme	628
647046398	649	32.33	148	642	8	515	3.0e-87	316	COG1640	4-alpha-glucanotransferase	520
647046399	869	42.75	1	866	1	888	0.0e+00	771	COG3280	Maltooligosyltrehalose synthase	889
647046401	720	53.73	10	708	10	696	0.0e+00	820	COG1523	Pullulanase/glycogen debranching enzyme	697
647046405	252	37.45	9	249	6	251	1.0e-37	149	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647046407	469	35.55	5	454	4	466	9.0e-73	267	COG4529	Uncharacterized NAD(P)/FAD-binding protein YdhS	474
647046413	430	40.28	9	428	33	456	5.0e-94	338	COG0513	Superfamily II DNA and RNA helicase	513
647046416	498	27.6	5	490	3	391	2.0e-60	226	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
647046418	356	52.94	34	355	2	324	8.0e-120	423	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
647046419	362	40.24	35	353	28	355	1.0e-87	316	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
647046420	1195	23.52	134	919	3	786	5.0e-38	154	COG2374	Predicted extracellular nuclease	798
647046421	306	52.69	29	288	3	260	1.0e-76	280	COG3483	Tryptophan 2,3-dioxygenase (vermilion)	262
647046422	502	39.09	8	502	2	498	5.0e-107	381	COG3104	Dipeptide/tripeptide permease	498
647046424	162	25.6	29	152	2	126	1.0e-13	69.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
647046425	356	53.78	1	356	9	359	2.0e-113	402	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
647046426	434	65.23	1	417	6	421	0.0e+00	563	COG3508	Homogentisate 1,2-dioxygenase	427
647046430	117	42.7	5	93	4	92	4.0e-18	83.4	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
647046431	94	45.88	5	89	1	85	2.0e-09	54.4	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
647046432	168	38.22	11	167	1	157	3.0e-30	124	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
647046433	514	30.16	1	504	1	498	2.0e-53	204	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
647046434	124	40.37	1	109	1	108	3.0e-21	94.1	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
647046435	938	43.05	3	588	3	581	3.0e-118	420	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
647046437	161	32.69	9	160	2	155	4.0e-15	74.2	COG4539	Uncharacterized membrane protein YGL010W	180
647046438	532	31.37	7	532	15	507	3.0e-75	276	COG3227	Zn-dependent metalloprotease	507
647046447	310	32.19	15	304	4	245	8.0e-63	234	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
647046450	223	57.66	1	222	1	220	5.0e-87	314	COG0036	Pentose-5-phosphate-3-epimerase	220
647046451	163	23.94	1	139	7	148	2.0e-06	45.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
647046452	309	38.76	5	307	4	301	2.0e-59	222	COG1597	Diacylglycerol kinase family enzyme	301
647046453	491	48.53	19	490	1	460	0.0e+00	506	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
647046454	353	33.43	9	348	1	340	1.0e-70	260	COG2008	Threonine aldolase	342
647046455	254	24.46	9	191	14	197	5.0e-12	64.9	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
647046456	192	61.26	1	191	3	189	3.0e-81	294	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
647046457	210	24.73	17	202	4	176	2.0e-26	112	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
647046458	345	51.03	2	340	1	338	4.0e-109	388	COG0547	Anthranilate phosphoribosyltransferase	338
647046459	265	55.04	5	262	1	254	6.0e-82	297	COG0134	Indole-3-glycerol phosphate synthase	254
647046460	238	24.55	8	220	1	200	2.0e-18	86.5	COG0560	Phosphoserine phosphatase	212
647046461	230	29.55	12	230	1	214	8.0e-30	123	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
647046463	264	42.94	7	182	1	135	9.0e-36	143	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
647046464	104	57.69	1	104	2	105	7.0e-22	95.5	COG2076	Multidrug transporter EmrE and related cation transporters	106
647046465	217	44.88	13	217	1	204	6.0e-59	220	COG2941	Demethoxyubiquinone hydroxylase, CLK1/Coq7/Cat5 family	204
647046466	142	61.54	1	142	1	143	9.0e-54	202	COG0102	Ribosomal protein L13	148
647046467	130	63.85	1	130	1	130	9.0e-47	178	COG0103	Ribosomal protein S9	130
647046470	200	21.62	13	156	17	155	7.0e-08	50.8	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
647046471	69	57.14	1	49	1	49	3.0e-11	60.3	COG2906	Bacterioferritin-associated ferredoxin	63
647046473	156	67.31	1	156	1	156	1.0e-57	215	COG2193	Bacterioferritin (cytochrome b1)	157
647046474	769	35.2	17	336	21	329	5.0e-45	176	COG0642	Signal transduction histidine kinase	336
647046475	656	29.79	407	640	3	236	1.0e-32	135	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
647046478	126	31.2	1	125	9	129	3.0e-20	90.8	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
647046479	128	55.14	22	128	4	110	5.0e-38	149	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
647046483	296	38.52	18	292	1	278	1.0e-57	216	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
647046484	296	35.03	4	293	2	279	6.0e-45	174	COG3725	Membrane protein required for beta-lactamase induction	282
647046488	640	31.12	408	597	2	194	4.0e-22	99	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
647046489	300	37.87	2	295	1	297	1.0e-28	120	COG0583	DNA-binding transcriptional regulator, LysR family	297
647046490	396	27.99	2	393	1	389	2.0e-25	110	COG2814	Predicted arabinose efflux permease, MFS family	394
647046491	737	32.12	12	720	4	664	1.0e-86	315	COG1289	Uncharacterized membrane protein YccC	674
647046493	431	62.79	1	428	1	428	0.0e+00	599	COG0151	Phosphoribosylamine-glycine ligase	428
647046495	435	31.1	36	398	2	362	1.0e-46	180	COG4637	Predicted ATPase	373
647046496	527	61.98	7	527	1	515	0.0e+00	734	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
647046498	90	48.86	2	89	10	97	1.0e-30	124	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
647046501	125	26.09	4	118	2	116	1.0e-05	41.9	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
647046503	310	40.97	1	305	2	300	5.0e-69	254	COG2264	Ribosomal protein L11 methylase PrmA	300
647046507	455	66.22	1	448	1	449	0.0e+00	626	COG0439	Biotin carboxylase	449
647046510	161	40	6	160	1	138	1.0e-24	105	COG0511	Biotin carboxyl carrier protein	140
647046511	148	55.48	3	148	2	146	2.0e-57	214	COG0757	3-dehydroquinate dehydratase	146
647046513	775	36.28	172	775	8	569	4.0e-118	419	COG4232	Thiol:disulfide interchange protein	569
647046514	110	49	8	107	5	104	6.0e-31	125	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
647046515	596	18.87	278	579	3	232	2.0e-19	91.2	COG2356	Endonuclease I	237
647046516	95	56.84	1	95	1	95	6.0e-29	119	COG0234	Co-chaperonin GroES (HSP10)	96
647046517	546	50.09	1	533	1	523	0.0e+00	506	COG0459	Chaperonin GroEL (HSP60 family)	524
647046525	279	30.29	15	252	61	296	2.0e-23	102	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
647046526	410	34.02	1	387	23	399	1.0e-74	273	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
647046532	417	30.3	8	417	9	436	7.0e-55	208	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
647046534	384	47.75	8	382	3	376	3.0e-114	405	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
647046535	342	42.01	9	341	3	340	6.0e-85	307	COG2222	Fructoselysine-6-P-deglycase FrlB and related proteins with duplicated sugar isomerase (SIS) domain	340
647046536	355	39	4	343	1	333	1.0e-78	286	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
647046537	425	36.06	1	415	3	409	4.0e-79	288	COG0738	Fucose permease	422
647046538	246	41.1	13	244	1	236	2.0e-51	196	COG2188	DNA-binding transcriptional regulator, GntR family	236
647046539	392	42.02	19	392	1	371	1.0e-87	316	COG4299	Predicted acyltransferase	371
647046542	963	19.88	56	640	14	619	2.0e-45	178	COG3250	Beta-galactosidase/beta-glucuronidase	808
647046544	902	17	1	900	3	767	1.0e-17	86.1	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647046548	394	38.62	17	389	1	370	3.0e-88	319	COG1565	SAM-dependent methyltransferase, MidA family	370
647046549	245	41.67	1	242	1	250	1.0e-38	153	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647046550	171	43.51	1	149	1	151	8.0e-32	129	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
647046551	500	29	107	367	71	335	9.0e-26	111	COG0642	Signal transduction histidine kinase	336
647046555	352	32.76	3	342	2	336	2.0e-51	196	COG0673	Predicted dehydrogenase	342
647046557	313	59.47	1	301	1	299	3.0e-111	395	COG1023	6-phosphogluconate dehydrogenase (decarboxylating)	300
647046559	124	36.15	1	122	1	130	4.0e-15	73.5	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
647046563	467	20.95	5	462	11	404	1.0e-50	194	COG1488	Nicotinic acid phosphoribosyltransferase	405
647046564	351	38.78	204	350	1	140	3.0e-25	109	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
647046565	288	21.72	35	288	10	259	8.0e-17	81.2	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
647046567	727	34.4	149	582	16	397	6.0e-79	289	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
647046568	337	62.3	34	336	5	306	0.0e+00	488	COG0320	Lipoate synthase	306
647046569	232	58.45	15	219	8	214	3.0e-79	288	COG0321	Lipoate-protein ligase B	221
647046570	92	38.2	5	92	2	90	6.0e-25	105	COG2921	Putative lipoic acid-binding regulatory protein	90
647046572	371	48.11	2	368	21	385	2.0e-110	392	COG1686	D-alanyl-D-alanine carboxypeptidase	389
647046575	380	31.93	25	379	1	342	3.0e-70	259	COG2951	Membrane-bound lytic murein transglycosylase B	343
647046582	565	64.9	15	487	1	467	0.0e+00	574	COG5297	Cellulase/cellobiase CelA1	544
647046587	372	37.74	11	370	6	375	9.0e-74	270	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
647046588	686	35.08	8	617	4	599	1.0e-129	457	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
647046589	161	35.67	6	161	8	164	3.0e-22	98.3	COG2891	Cell shape-determining protein MreD	167
647046591	339	35.19	17	283	8	277	8.0e-58	217	COG1792	Cell shape-determining protein MreC	284
647046592	348	68.31	5	346	1	341	0.0e+00	484	COG1077	Actin-like ATPase involved in cell morphogenesis	342
647046593	310	25.87	36	306	26	311	9.0e-35	141	COG0524	Sugar or nucleoside kinase, ribokinase family	311
647046597	310	28.37	17	302	6	289	5.0e-56	211	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
647046598	405	34.21	15	166	18	167	3.0e-26	113	COG4032	Sulfopyruvate decarboxylase, TPP-binding subunit (coenzyme M biosynthesis)	172
647046600	250	26.07	1	228	4	227	7.0e-23	101	COG1213	Choline kinase	239
647046601	672	29.04	1	628	1	538	1.0e-96	347	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
647046602	484	39.92	13	481	5	472	5.0e-108	385	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647046603	279	27.54	4	279	3	256	5.0e-08	51.9	COG0730	Uncharacterized membrane protein YfcA	258
647046608	187	26.57	1	182	11	216	2.0e-16	79.4	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
647046610	674	21.6	64	653	18	646	2.0e-82	300	COG0308	Aminopeptidase N	859
647046611	296	34.08	111	283	1	179	2.0e-27	116	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
647046612	253	54.58	15	253	1	238	3.0e-83	301	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
647046614	362	41.14	10	357	7	340	5.0e-64	238	COG1566	Multidrug resistance efflux pump	352
647046615	211	50.99	53	203	2	152	1.0e-50	192	COG2153	Predicted N-acyltransferase, GNAT family	155
647046616	151	34.78	3	114	4	118	2.0e-21	95.4	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
647046617	447	69.04	1	447	4	444	0.0e+00	678	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
647046618	183	72	10	183	2	175	1.0e-69	255	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
647046620	305	58	4	301	10	299	7.0e-106	377	COG4973	Site-specific recombinase XerC	299
647046623	226	35.59	8	226	1	218	9.0e-45	173	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
647046624	284	46.91	10	284	1	272	4.0e-81	294	COG0253	Diaminopimelate epimerase	272
647046626	132	39.32	8	123	3	119	6.0e-19	86.4	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
647046627	669	54.29	6	667	19	680	0.0e+00	870	COG1770	Protease II	682
647046628	394	37.15	13	394	1	392	8.0e-91	327	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
647046630	697	42.84	29	696	4	648	0.0e+00	638	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
647046632	189	27.04	2	160	3	159	1.0e-18	86.2	COG3040	Bacterial lipocalin	174
647046633	321	31.15	1	321	4	310	2.0e-47	182	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
647046635	266	34.33	1	265	10	262	4.0e-49	188	COG3137	Putative salt-induced outer membrane protein YdiY	262
647046636	304	55.41	1	304	1	305	3.0e-105	375	COG0181	Porphobilinogen deaminase	307
647046637	245	40.57	6	245	2	244	4.0e-48	184	COG3279	DNA-binding response regulator, LytR/AlgR family	244
647046638	350	25.65	10	349	112	452	3.0e-45	176	COG2972	Sensor histidine kinase YesM	456
647046639	222	30	1	219	3	206	5.0e-39	154	COG0400	Predicted esterase	207
647046640	645	48.2	8	638	5	642	0.0e+00	791	COG2943	Membrane glycosyltransferase	736
647046646	495	33.66	17	485	23	527	4.0e-86	312	COG0659	Sulfate permease or related transporter, MFS superfamily	554
647046648	476	27.27	1	375	1	398	4.0e-48	186	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
647046649	745	38.53	396	710	69	408	1.0e-52	202	COG0840	Methyl-accepting chemotaxis protein	408
647046651	922	41.48	740	914	2	175	3.0e-35	144	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
647046652	959	28.02	505	939	4	438	4.0e-69	256	COG0612	Predicted Zn-dependent peptidase	438
647046658	275	24.55	26	268	1	273	2.0e-25	109	COG0266	Formamidopyrimidine-DNA glycosylase	273
647046659	247	33.07	1	247	3	252	1.0e-45	177	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
647046661	557	52.02	24	536	32	552	0.0e+00	556	COG1626	Neutral trehalase	558
647046663	231	31.55	30	230	18	219	5.0e-32	131	COG2013	Uncharacterized conserved protein, AIM24 family	227
647046664	300	25.94	13	299	34	321	3.0e-48	185	COG0598	Mg2+ and Co2+ transporter CorA	322
647046668	589	70.73	385	589	27	231	7.0e-91	328	COG4305	Peptidoglycan-binding domain, expansin	232
647046670	257	27.44	1	257	3	266	2.0e-28	119	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
647046671	291	24.01	1	267	5	274	9.0e-07	47.8	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
647046672	355	37.89	74	352	8	287	3.0e-77	282	COG2521	Predicted archaeal methyltransferase	287
647046675	682	43.27	513	681	11	180	2.0e-31	131	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
647046679	770	20	165	745	23	607	1.0e-41	164	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
647046682	153	30.72	1	151	1	153	3.0e-07	48	COG3918	Uncharacterized membrane protein	153
647046683	324	68.83	1	323	1	321	0.0e+00	539	COG0435	Glutathionyl-hydroquinone reductase	324
647046698	272	30.77	22	268	1	228	4.0e-17	82	COG2801	Transposase InsO and inactivated derivatives	232
647046700	403	26.79	1	209	2	207	2.0e-20	93.8	COG5278	Extracellular (periplasmic) sensor domain CHASE3 (specificity unknown)	207
647046701	327	43.88	3	271	115	408	4.0e-31	128	COG0840	Methyl-accepting chemotaxis protein	408
647046705	752	41.3	383	696	70	408	2.0e-52	201	COG0840	Methyl-accepting chemotaxis protein	408
647046706	776	36.07	365	735	7	408	1.0e-47	185	COG0840	Methyl-accepting chemotaxis protein	408
647046708	910	41.64	556	859	80	408	1.0e-55	211	COG0840	Methyl-accepting chemotaxis protein	408
647046713	191	46.84	1	188	1	189	3.0e-49	188	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
647046714	169	25.42	1	169	2	176	1.0e-19	89.3	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
647046715	64	49.12	1	56	1	57	3.0e-12	63.3	COG0333	Ribosomal protein L32	57
647046716	325	61.49	5	325	2	322	3.0e-122	431	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
647046718	314	51.31	7	311	5	310	4.0e-92	331	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
647046719	247	45.82	5	244	3	250	2.0e-45	176	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647046720	79	65.38	1	78	3	80	4.0e-13	66.5	COG0236	Acyl carrier protein	80
647046722	411	56.17	1	411	1	411	0.0e+00	496	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
647046725	357	42.73	14	347	9	342	4.0e-98	351	COG1559	Cell division protein YceG, involved in septum cleavage	342
647046727	117	63.25	1	117	2	117	6.0e-42	162	COG3215	Tfp pilus assembly protein PilZ	117
647046729	83	56.63	1	83	1	83	2.0e-24	104	COG4115	Toxin component of the Txe-Axe toxin-antitoxin module, Txe/YoeB family	84
647046730	83	46.75	1	75	3	79	2.0e-12	64.3	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
647046733	298	59.86	6	294	3	289	1.0e-93	336	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
647046734	198	42.6	24	191	4	168	4.0e-36	144	COG4420	Uncharacterized membrane protein	191
647046735	388	46.49	10	387	9	390	2.0e-118	418	COG0372	Citrate synthase	390
647046737	864	49.31	1	859	1	861	0.0e+00	1080	COG1048	Aconitase A	861
647046739	399	64.62	5	393	2	375	0.0e+00	514	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
647046741	738	15.92	1	738	16	768	1.0e-25	111	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647046743	296	29.02	3	292	2	307	1.0e-34	139	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
647046744	1625	36.39	5	1625	29	1621	0.0e+00	1162	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
647046748	761	49.74	1	761	18	733	0.0e+00	800	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
647046750	186	30.5	42	181	6	139	5.0e-25	107	COG2193	Bacterioferritin (cytochrome b1)	157
647046751	160	47.88	1	158	1	165	8.0e-53	199	COG0678	Peroxiredoxin	165
647046752	158	33.6	22	146	22	143	3.0e-24	104	COG0071	Molecular chaperone IbpA, HSP20 family	146
647046758	392	32.33	69	327	8	272	1.0e-41	164	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
647046759	287	30.45	5	286	5	286	1.0e-39	156	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
647046760	430	62.33	2	430	1	430	0.0e+00	651	COG0104	Adenylosuccinate synthase	430
647046761	889	26.56	49	875	25	855	6.0e-101	362	COG0308	Aminopeptidase N	859
647046766	450	18.89	8	413	1	391	1.0e-19	91.6	COG0732	Restriction endonuclease S subunit	391
647046767	514	27.06	1	490	2	489	1.0e-67	251	COG0286	Type I restriction-modification system, DNA methylase subunit	489
647046768	400	28.73	10	378	1	347	7.0e-60	224	COG3177	Fic family protein	348
647046769	1183	26	266	1181	1	873	1.0e-122	434	COG4096	Type I site-specific restriction endonuclease, part of a restriction-modification system	875
647046777	259	29.02	19	242	4	205	5.0e-24	104	COG0406	Broad specificity phosphatase PhoE	208
647046778	289	35.42	3	286	6	284	1.0e-37	150	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
647046779	499	25.73	64	496	16	427	9.0e-53	201	COG5520	O-Glycosyl hydrolase	433
647046780	601	27.51	17	599	15	605	2.0e-65	244	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
647046781	300	36.9	51	298	1	251	2.0e-54	205	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647046785	234	42.51	1	232	7	250	1.0e-57	216	COG0631	Serine/threonine protein phosphatase PrpC	262
647046787	244	35.78	1	230	13	236	2.0e-41	162	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
647046788	150	55.78	1	144	1	147	8.0e-47	179	COG0328	Ribonuclease HI	154
647046790	255	29.31	4	200	17	248	2.0e-19	89.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647046795	90	66.67	1	90	2	91	4.0e-27	112	COG0776	Bacterial nucleoid DNA-binding protein	94
647046796	823	64.94	7	794	6	781	0.0e+00	1175	COG0466	ATP-dependent Lon protease, bacterial type	782
647046798	428	72.62	19	426	1	408	0.0e+00	702	COG1219	ATP-dependent protease Clp, ATPase subunit	408
647046799	208	70.05	9	205	2	198	6.0e-85	306	COG0740	ATP-dependent protease ClpP, protease subunit	200
647046800	430	33.64	1	426	1	435	7.0e-86	311	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
647046802	422	22.25	81	420	4	331	3.0e-24	106	COG0642	Signal transduction histidine kinase	336
647046808	253	41.52	3	252	4	276	3.0e-63	235	COG4760	Uncharacterized membrane protein, YccA/Bax inhibitor family	276
647046809	335	50	1	335	2	345	1.0e-121	429	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
647046810	131	29.35	32	122	33	124	7.0e-14	69.7	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
647046811	102	40	14	91	1	80	2.0e-18	83.9	COG0695	Glutaredoxin	80
647046814	229	44.05	3	225	1	225	7.0e-61	227	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647046815	442	31.3	73	421	91	443	4.0e-45	176	COG5002	Signal transduction histidine kinase	459
647046817	700	54.43	17	698	1	684	0.0e+00	905	COG0855	Polyphosphate kinase	696
647046818	506	40.82	15	492	5	487	4.0e-114	405	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
647046820	378	25.32	1	370	1	381	7.0e-37	148	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
647046823	247	47.35	4	247	1	236	1.0e-68	252	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
647046827	278	52.71	13	270	3	259	4.0e-79	288	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
647046828	488	53.09	1	480	4	470	0.0e+00	592	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
647046829	259	34.46	1	171	3	179	9.0e-29	120	COG1286	Uncharacterized membrane protein, required for colicin V production	182
647046830	354	30.77	186	354	59	226	4.0e-16	79.3	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
647046831	432	40.28	1	424	1	417	1.0e-106	380	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
647046833	214	41.27	1	187	3	189	2.0e-37	148	COG0406	Broad specificity phosphatase PhoE	208
647046834	693	40.32	6	538	5	521	3.0e-121	429	COG3511	Phospholipase C	527
647046835	777	19.95	10	777	12	768	1.0e-23	105	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647046836	340	37.39	1	339	1	350	1.0e-75	276	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
647046838	344	56	1	344	1	345	2.0e-114	405	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
647046839	317	65.17	28	317	12	287	6.0e-105	374	COG4208	ABC-type sulfate transport system, permease component	287
647046840	286	55.11	10	283	1	274	2.0e-75	275	COG0555	ABC-type sulfate transport system, permease component	274
647046841	365	65.2	30	363	6	345	0.0e+00	520	COG1613	ABC-type sulfate transport system, periplasmic component	348
647046843	402	45.85	10	394	5	388	6.0e-117	414	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
647046845	285	39.09	39	275	5	242	4.0e-55	208	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
647046847	365	32.61	180	363	12	187	1.0e-30	127	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
647046848	340	33.92	1	338	1	325	5.0e-59	221	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647046849	679	40.88	11	364	2	362	7.0e-95	341	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
647046850	438	18.16	17	412	14	433	6.0e-06	46	COG2211	Na+/melibiose symporter or related transporter	467
647046855	204	31.4	1	201	1	205	5.0e-22	98	COG0625	Glutathione S-transferase	211
647046858	164	59.85	4	136	1	137	2.0e-52	198	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
647046859	609	66.83	3	608	2	602	0.0e+00	977	COG1217	Predicted membrane GTPase involved in stress response	603
647046860	156	30.14	13	154	5	145	2.0e-25	108	COG3305	Uncharacterized membrane protein, DUF2068 family	152
647046861	896	24.17	30	884	9	808	2.0e-126	447	COG3250	Beta-galactosidase/beta-glucuronidase	808
647046862	767	36.78	6	616	118	732	0.0e+00	537	COG3525	N-acetyl-beta-hexosaminidase	732
647046864	349	32.86	3	346	84	420	4.0e-80	291	COG3858	Spore germination protein YaaH	423
647046865	561	37.18	114	540	1	411	6.0e-99	355	COG3669	Alpha-L-fucosidase	430
647046869	338	38.56	18	336	8	320	2.0e-72	265	COG0837	Glucokinase	320
647046870	244	43.72	1	243	1	246	5.0e-64	237	COG1385	16S rRNA U1498 N3-methylase RsmE	246
647046871	472	45.73	19	472	1	448	0.0e+00	518	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
647046872	182	30	46	163	12	129	5.0e-06	44.6	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
647046873	266	50.55	1	266	1	274	1.0e-77	283	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
647046875	111	64.42	7	109	4	107	3.0e-26	110	COG1742	Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily	109
647046877	123	40.16	2	122	23	140	2.0e-17	81.1	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
647046878	369	49.34	1	364	4	377	5.0e-110	391	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
647046879	131	61.54	1	129	2	131	1.0e-40	158	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
647046883	459	28.77	53	398	15	362	2.0e-34	140	COG1680	CubicO group peptidase, beta-lactamase class C family	390
647046885	440	16.67	9	405	27	460	4.0e-24	106	COG3202	ATP/ADP translocase	509
647046886	117	50.83	1	115	1	120	9.0e-23	98.7	COG3759	Uncharacterized membrane protein	121
647046889	431	29.65	122	430	3	303	6.0e-38	152	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647046890	307	24.62	35	287	22	282	1.0e-13	70.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647046891	203	24.58	12	188	1	179	1.0e-09	56.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647046894	296	45.94	1	273	1	278	8.0e-68	250	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
647046896	345	28.57	15	303	4	289	9.0e-22	97.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
647046898	198	32.35	1	99	18	117	3.0e-14	71.7	COG0517	CBS domain	117
647046899	661	26.34	25	633	1	637	3.0e-59	223	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
647046900	214	46.86	10	213	17	223	1.0e-47	182	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
647046901	534	68.12	1	527	2	528	0.0e+00	865	COG4108	Peptide chain release factor RF-3	528
647046903	342	30.93	44	337	35	367	8.0e-67	247	COG2021	Homoserine acetyltransferase	368
647046904	405	52.58	14	391	9	395	0.0e+00	463	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
647046905	362	33.05	21	362	5	329	1.0e-49	190	COG0460	Homoserine dehydrogenase	333
647046906	335	26.44	52	335	9	281	3.0e-22	99.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647046908	460	52.48	175	456	1	262	2.0e-90	326	COG1760	L-serine deaminase	262
647046911	94	42.31	5	55	4	55	1.0e-05	41.7	COG1278	Cold shock protein, CspA family	67
647046912	189	31.91	10	187	5	192	1.0e-29	123	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
647046913	187	47.16	7	181	6	180	3.0e-40	158	COG3038	Cytochrome b561	181
647046914	220	40.31	5	194	3	192	2.0e-40	159	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
647046915	1191	36.52	19	702	20	671	2.0e-91	331	COG3292	Periplasmic ligand-binding sensor domain	671
647046917	1171	30.41	10	699	8	671	6.0e-60	226	COG3292	Periplasmic ligand-binding sensor domain	671
647046921	666	23.81	3	666	20	646	4.0e-37	150	COG3292	Periplasmic ligand-binding sensor domain	671
647046936	324	23.2	9	193	30	192	1.0e-12	67.3	COG2184	Fido, protein-threonine AMPylation domain	201
647046955	211	33.5	3	204	63	254	1.0e-35	142	COG3757	Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family	269
647046964	406	31.93	6	375	4	346	2.0e-40	160	COG0675	Transposase	364
647046965	137	39.1	6	137	1	133	2.0e-35	141	COG1943	REP element-mobilizing transposase RayT	136
647046973	524	17.67	96	524	102	562	5.0e-23	102	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
647046979	243	42.48	21	243	4	224	3.0e-42	165	COG1040	Predicted amidophosphoribosyltransferases	225
647046980	344	59.25	6	322	11	327	2.0e-122	432	COG0502	Biotin synthase or related enzyme	335
647046981	401	44.07	4	388	1	387	2.0e-108	386	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
647046983	253	29.21	4	252	16	282	3.0e-12	65.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647046984	260	35	3	254	1	249	2.0e-28	119	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647046987	301	50.17	5	296	1	291	4.0e-92	331	COG3555	Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily	291
647046990	205	26.52	17	196	24	202	7.0e-18	84.1	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
647046991	319	37.07	1	315	1	321	1.0e-65	243	COG1171	Threonine dehydratase	347
647046995	634	60.8	8	632	5	621	0.0e+00	951	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
647046996	322	37.63	1	293	1	293	5.0e-44	172	COG0657	Acetyl esterase/lipase	312
647046998	286	29.57	1	220	21	243	2.0e-38	153	COG1718	Serine/threonine-protein kinase RIO1	268
647046999	286	37.96	43	285	1	244	4.0e-47	181	COG1414	DNA-binding transcriptional regulator, IclR family	246
647047000	134	46.34	9	128	2	124	9.0e-22	95.9	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
647047002	261	26.69	1	257	2	279	4.0e-17	82.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647047003	450	39.91	12	445	5	437	7.0e-105	374	COG0015	Adenylosuccinate lyase	438
647047005	187	44.28	2	186	26	225	6.0e-39	154	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
647047006	229	45.33	6	229	9	224	1.0e-52	199	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
647047008	402	43.58	1	402	1	392	7.0e-83	301	COG0183	Acetyl-CoA acetyltransferase	392
647047009	262	30	1	235	2	224	6.0e-54	204	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
647047010	287	31.76	1	228	1	220	2.0e-48	186	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
647047011	301	19.13	1	285	52	333	4.0e-24	105	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
647047013	275	40	21	270	4	253	2.0e-67	249	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
647047016	504	52.39	3	477	11	489	0.0e+00	540	COG0578	Glycerol-3-phosphate dehydrogenase	532
647047017	273	40.24	4	254	3	241	7.0e-49	187	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
647047018	499	67.81	1	497	2	497	0.0e+00	817	COG0554	Glycerol kinase	499
647047019	181	45.22	55	169	4	111	1.0e-24	105	COG4922	Predicted SnoaL-like aldol condensation-catalyzing enzyme	129
647047020	394	27.41	1	387	1	385	2.0e-54	206	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
647047021	300	28.81	180	297	2	119	6.0e-15	75.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647047022	255	28.93	1	251	1	251	6.0e-22	98	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647047023	158	22.76	34	154	4	126	1.0e-08	53	COG1846	DNA-binding transcriptional regulator, MarR family	126
647047026	415	35.12	40	368	12	344	2.0e-65	243	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
647047027	436	24.76	17	436	8	391	3.0e-13	70.2	COG2814	Predicted arabinose efflux permease, MFS family	394
647047029	181	47.43	1	175	1	168	4.0e-54	203	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
647047034	612	53.82	1	610	8	575	0.0e+00	782	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
647047035	314	29.68	29	295	20	262	1.0e-21	97.6	COG4974	Site-specific recombinase XerD	300
647047044	143	40	22	131	11	120	4.0e-30	123	COG1733	DNA-binding transcriptional regulator, HxlR family	120
647047045	286	33.81	1	270	2	275	4.0e-23	102	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
647047050	342	30.46	1	339	1	330	4.0e-68	252	COG0620	Methionine synthase II (cobalamin-independent)	330
647047052	180	31.95	1	164	10	176	3.0e-21	94.7	COG0431	NAD(P)H-dependent FMN reductase	184
647047053	304	32.18	6	292	5	289	5.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
647047054	221	59.02	14	217	1	204	3.0e-87	314	COG1636	Predicted ATPase, Adenine nucleotide alpha hydrolases (AANH) superfamily	204
647047055	299	25.53	55	284	66	290	2.0e-23	103	COG0685	5,10-methylenetetrahydrofolate reductase	291
647047058	289	58.21	11	289	8	287	5.0e-118	417	COG0788	Formyltetrahydrofolate hydrolase	287
647047061	292	38.46	1	283	1	284	2.0e-53	202	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
647047062	372	41.28	11	349	6	336	4.0e-89	321	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
647047063	293	32.34	10	273	3	241	5.0e-49	188	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
647047064	210	21.99	10	197	1	190	3.0e-07	48.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647047065	239	31.9	1	227	1	219	5.0e-29	121	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647047067	426	25.59	32	408	16	388	6.0e-23	102	COG2814	Predicted arabinose efflux permease, MFS family	394
647047068	295	39.06	1	295	1	291	6.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
647047073	354	54.37	1	354	4	351	2.0e-122	432	COG0407	Uroporphyrinogen-III decarboxylase	352
647047075	370	52.25	14	369	9	355	1.0e-118	419	COG0337	3-dehydroquinate synthetase	360
647047076	180	45.61	3	173	1	170	4.0e-48	184	COG0703	Shikimate kinase	172
647047077	199	52.06	6	199	25	214	4.0e-63	233	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
647047078	138	37.96	24	131	29	136	5.0e-22	97	COG3789	Uncharacterized protein YjfI, DUF2170 family	146
647047079	257	28.95	1	228	1	224	6.0e-16	78	COG1842	Phage shock protein A	225
647047082	134	39.68	8	133	7	132	9.0e-21	92.6	COG3766	Uncharacterized membrane protein YjfL, UPF0719 family	133
647047083	190	29.63	3	180	18	197	1.0e-12	66.2	COG5463	Uncharacterized conserved protein YgiB, involved in bioifilm formation, UPF0441/DUF1190 family	198
647047084	388	52.56	1	388	1	387	0.0e+00	469	COG0754	Glutathionylspermidine synthase	387
647047087	148	34.17	5	119	1	120	5.0e-17	80.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
647047095	334	27.91	58	334	4	289	2.0e-46	179	COG1234	Ribonuclease BN, tRNA processing enzyme	292
647047102	322	29.14	51	211	16	187	7.0e-17	81.4	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
647047112	343	30.63	7	336	1	286	9.0e-54	204	COG4823	Abortive infection bacteriophage resistance protein	299
647047113	216	26.07	12	206	3	198	2.0e-13	69.4	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
647047117	460	27.25	20	443	8	444	3.0e-30	126	COG0531	Amino acid transporter	466
647047120	313	27.59	7	292	4	280	5.0e-18	85.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647047127	466	42.79	1	438	2	443	8.0e-122	430	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
647047128	338	43.39	1	338	1	346	5.0e-67	248	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
647047130	453	45.35	13	452	8	448	2.0e-118	419	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
647047132	576	44.97	4	568	2	567	0.0e+00	602	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
647047133	89	47.73	1	88	1	88	3.0e-21	93.3	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
647047134	130	36.64	3	130	2	131	1.0e-20	91.9	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
647047136	290	49.47	7	290	2	284	3.0e-101	361	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
647047137	316	40.13	3	316	1	307	6.0e-92	331	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
647047138	152	36.09	17	144	17	149	1.0e-22	98.9	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
647047139	105	42.99	1	105	1	107	1.0e-21	94.9	COG1544	Ribosome-associated translation inhibitor RaiA	110
647047140	479	43.54	1	478	1	443	3.0e-125	442	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
647047141	239	67.5	1	239	4	243	2.0e-106	378	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
647047142	183	33.33	1	164	4	169	1.0e-28	119	COG1934	Lipopolysaccharide export system protein LptA	173
647047143	191	25.13	1	191	2	188	1.0e-32	132	COG3117	Lipopolysaccharide export system protein LptC	188
647047144	182	50.92	13	174	1	163	1.0e-55	209	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
647047145	333	52.26	18	215	3	201	4.0e-62	232	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
647047146	75	45.33	1	74	1	74	2.0e-20	90.3	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
647047147	424	63.74	1	422	1	417	0.0e+00	622	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
647047151	222	52	8	205	1	200	6.0e-64	237	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
647047153	341	59.48	1	341	4	344	0.0e+00	479	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
647047154	370	26.95	2	370	1	343	2.0e-54	206	COG3249	Uncharacterized protein	343
647047155	388	32.67	12	363	13	353	8.0e-42	164	COG0628	Predicted PurR-regulated permease PerM	355
647047159	339	41.95	1	333	4	349	9.0e-80	290	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
647047160	90	35	9	87	2	81	1.0e-06	45	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
647047161	497	22.2	10	452	7	389	2.0e-23	104	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647047164	485	29.87	4	485	97	587	6.0e-75	275	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
647047166	339	40.32	28	336	27	336	1.0e-76	279	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
647047167	267	20	1	265	1	259	4.0e-08	52.3	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
647047168	171	51.48	2	170	4	170	3.0e-54	204	COG3656	Predicted periplasmic protein	172
647047169	213	51.23	10	212	15	213	1.0e-54	205	COG3295	Uncharacterized protein	213
647047171	228	57.46	1	228	3	229	1.0e-80	292	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
647047172	670	37.41	1	670	124	750	9.0e-126	444	COG4774	Outer membrane receptor for monomeric catechols	750
647047175	109	30.56	1	108	1	106	2.0e-19	87.3	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
647047178	414	52.84	10	410	1	403	3.0e-130	458	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
647047179	420	29.65	29	399	33	395	1.0e-70	260	COG0719	Fe-S cluster assembly scaffold protein SufB	412
647047180	254	63.1	1	251	3	250	1.0e-102	366	COG0396	Fe-S cluster assembly ATPase SufC	251
647047181	485	41.48	42	483	1	412	2.0e-125	443	COG0719	Fe-S cluster assembly scaffold protein SufB	412
647047182	152	36.84	2	133	1	133	3.0e-26	111	COG1959	DNA-binding transcriptional regulator, IscR family	150
647047184	180	40	7	180	2	184	8.0e-25	106	COG0693	Putative intracellular protease/amidase	188
647047190	286	45.11	18	282	3	264	2.0e-67	249	COG0345	Pyrroline-5-carboxylate reductase	266
647047191	230	48.43	3	222	4	226	3.0e-66	244	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
647047192	345	68.13	1	341	3	344	0.0e+00	549	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
647047193	376	65.78	1	374	2	375	0.0e+00	598	COG5008	Tfp pilus assembly protein, ATPase PilU	375
647047196	298	34.88	1	294	1	254	9.0e-59	220	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
647047197	190	37.3	4	168	3	186	1.0e-43	169	COG2818	3-methyladenine DNA glycosylase Tag	188
647047199	188	50.82	8	188	13	194	6.0e-57	213	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
647047200	155	37.96	11	146	2	135	1.0e-29	122	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
647047201	315	47.32	6	314	1	311	1.0e-96	346	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
647047204	144	31.43	7	141	4	143	4.0e-23	100	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
647047207	293	38.51	1	290	1	289	3.0e-52	198	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
647047208	869	36.46	9	462	2	447	1.0e-100	361	COG0527	Aspartokinase	447
647047211	468	33.55	3	457	2	448	3.0e-94	339	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
647047212	266	28.88	38	266	10	236	3.0e-29	122	COG0412	Dienelactone hydrolase	236
647047213	332	38.46	15	332	2	322	9.0e-77	280	COG0142	Geranylgeranyl pyrophosphate synthase	322
647047214	181	36.61	4	181	2	167	1.0e-32	132	COG0629	Single-stranded DNA-binding protein	167
647047219	335	37.86	1	335	1	326	2.0e-54	206	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647047221	189	53.57	23	189	3	155	7.0e-55	206	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
647047222	316	40	1	316	1	281	3.0e-57	215	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
647047223	735	38.04	13	731	1	731	0.0e+00	541	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
647047224	350	29.9	28	327	1	257	2.0e-32	133	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
647047225	202	29.29	1	196	2	196	8.0e-18	83.8	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
647047232	225	36.49	3	220	2	220	7.0e-34	137	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
647047235	74	61.67	15	74	6	65	5.0e-19	85.7	COG2879	Uncharacterized short protein YbdD, DUF466 family	65
647047236	690	42.99	31	683	1	573	0.0e+00	584	COG1966	Carbon starvation protein CstA	575
647047237	285	44.64	11	285	7	275	4.0e-64	238	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
647047238	144	28.36	6	134	4	137	2.0e-16	78.1	COG1765	Uncharacterized OsmC-related protein	137
647047241	296	39.78	3	272	10	276	3.0e-58	218	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
647047242	235	49.07	11	224	2	212	4.0e-66	244	COG1515	Deoxyinosine 3'endonuclease (endonuclease V)	212
647047243	249	68.7	2	231	1	230	2.0e-101	362	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
647047246	709	46.46	64	709	9	654	0.0e+00	718	COG3590	Predicted metalloendopeptidase	654
647047247	520	28.99	7	478	1	416	4.0e-63	235	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
647047249	373	50.28	18	372	1	343	4.0e-98	351	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
647047250	268	37.41	9	267	1	265	3.0e-59	222	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
647047251	427	43.87	161	412	5	256	1.0e-67	251	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
647047252	171	32.93	5	168	5	164	3.0e-29	121	COG0835	Chemotaxis signal transduction protein	165
647047253	707	38.72	362	650	81	408	5.0e-41	163	COG0840	Methyl-accepting chemotaxis protein	408
647047254	669	39.21	1	658	4	707	0.0e+00	552	COG0643	Chemotaxis protein histidine kinase CheA	716
647047255	109	28.87	1	94	3	99	7.0e-07	45.8	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
647047257	1154	50.31	9	1153	1	1135	0.0e+00	1402	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
647047259	180	16.88	22	173	10	166	9.0e-06	43.4	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
647047260	302	47.33	1	299	1	277	4.0e-95	341	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
647047261	482	26.33	166	481	20	329	5.0e-37	149	COG0642	Signal transduction histidine kinase	336
647047266	294	29.31	1	285	3	272	4.0e-24	105	COG0388	Predicted amidohydrolase	274
647047268	467	42.86	4	463	11	472	9.0e-129	454	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
647047269	168	36.23	29	165	8	140	3.0e-27	114	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
647047271	213	25.12	1	207	2	201	4.0e-14	71.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647047273	404	34.72	1	382	1	372	7.0e-34	138	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
647047274	1047	55.83	1	1027	2	1006	0.0e+00	1052	COG0841	Multidrug efflux pump subunit AcrB	1009
647047275	501	39.29	45	492	14	456	2.0e-67	250	COG1538	Outer membrane protein TolC	457
647047277	385	30	37	229	1	176	3.0e-13	69.8	COG3039	Transposase and inactivated derivatives, IS5 family	230
647047280	392	35.68	2	388	32	443	2.0e-80	293	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
647047289	933	56.15	333	933	1	593	0.0e+00	794	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
647047291	229	39.74	1	221	1	227	3.0e-47	181	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647047292	463	26.81	129	459	2	328	2.0e-35	143	COG0642	Signal transduction histidine kinase	336
647047293	291	29.21	4	268	3	242	7.0e-34	137	COG1647	Esterase/lipase	243
647047298	467	32.59	21	465	23	447	1.0e-84	307	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
647047299	233	24.31	5	217	6	218	2.0e-23	103	COG4359	2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase (methionine salvage)	220
647047302	299	64	1	298	4	303	3.0e-130	458	COG0408	Coproporphyrinogen III oxidase	303
647047304	263	21.36	84	260	73	277	8.0e-11	61.1	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
647047308	276	36.19	3	264	7	273	1.0e-49	190	COG3220	Uncharacterized conserved protein, UPF0276 family	282
647047317	786	24.57	216	785	96	618	2.0e-65	244	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
647047319	435	20.26	7	429	66	516	4.0e-38	152	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
647047322	461	21.62	26	436	5	394	3.0e-30	126	COG0644	Dehydrogenase (flavoprotein)	396
647047325	249	35.75	31	248	16	230	1.0e-27	116	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
647047327	324	45.16	2	306	1	309	1.0e-96	346	COG4261	Predicted acyltransferase, LPLAT superfamily	309
647047329	806	38.1	28	793	15	784	0.0e+00	617	COG4258	Predicted exporter	788
647047330	153	28.47	7	150	12	147	4.0e-18	83.9	COG4706	Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain	161
647047332	245	45.16	8	244	6	250	1.0e-37	149	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647047335	540	22.07	7	375	5	335	3.0e-21	97.1	COG0644	Dehydrogenase (flavoprotein)	396
647047336	273	19.26	13	248	7	240	7.0e-13	67.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
647047338	399	34.29	1	397	2	410	9.0e-72	264	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
647047339	86	37.84	1	74	11	84	4.0e-16	76.2	COG3100	Uncharacterized conserved protein YcgL, UPF0745 family	103
647047341	1054	25.67	185	444	1	203	2.0e-14	75.3	COG0666	Ankyrin repeat	235
647047342	108	60.19	1	103	5	107	2.0e-30	124	COG4551	Predicted protein tyrosine phosphatase	109
647047343	599	31.35	4	588	15	604	9.0e-102	364	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
647047344	608	47.31	6	502	4	481	0.0e+00	574	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
647047345	603	40.91	1	389	3	394	4.0e-63	236	COG0475	Kef-type K+ transport system, membrane component KefB	397
647047348	455	38.46	13	454	22	451	1.0e-106	380	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
647047350	902	40.47	5	637	3	598	2.0e-108	387	COG1042	Acyl-CoA synthetase (NDP forming)	598
647047351	341	58.24	2	339	10	346	1.0e-115	409	COG2899	Uncharacterized protein	346
647047353	827	34.27	93	826	1	654	0.0e+00	593	COG0209	Ribonucleotide reductase alpha subunit	696
647047354	349	34.68	10	348	1	343	7.0e-84	304	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
647047357	160	26.53	1	139	2	143	8.0e-14	70	COG0716	Flavodoxin	151
647047364	312	33.65	1	312	1	305	1.0e-59	223	COG1893	Ketopantoate reductase	307
647047366	263	27.7	1	262	9	286	9.0e-11	61.1	COG0842	ABC-type multidrug transport system, permease component	286
647047367	319	37.5	3	297	9	292	3.0e-69	255	COG1131	ABC-type multidrug transport system, ATPase component	293
647047368	240	30.13	3	230	17	228	3.0e-31	128	COG1018	Ferredoxin-NADP reductase	266
647047369	326	34.06	4	319	1	294	5.0e-58	218	COG1230	Co/Zn/Cd efflux system component	296
647047370	90	44.94	1	89	1	89	4.0e-18	83	COG1937	DNA-binding transcriptional regulator, FrmR family	89
647047372	66	52.31	1	65	2	66	3.0e-20	89.9	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
647047374	248	55.24	1	248	1	245	2.0e-88	319	COG4555	ABC-type Na+ transport system, ATPase component NatA	245
647047375	397	27.83	7	397	1	401	2.0e-34	140	COG1668	ABC-type Na+ efflux pump, permease component	407
647047383	229	36.06	1	202	1	201	8.0e-36	143	COG0625	Glutathione S-transferase	211
647047384	745	24.27	104	740	8	617	4.0e-56	213	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
647047390	331	60.3	1	329	3	330	0.0e+00	516	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
647047394	304	31.56	5	296	1	297	3.0e-23	102	COG0583	DNA-binding transcriptional regulator, LysR family	297
647047400	612	28.6	72	605	32	554	5.0e-68	252	COG5519	Uncharcterized protein, DUF927 family	562
647047410	396	18.57	86	385	5	303	1.0e-08	54.2	COG0582	Integrase	309
647047413	624	55.63	323	622	42	342	1.0e-98	354	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
647047415	146	56.94	1	144	1	143	4.0e-53	200	COG1490	D-Tyr-tRNAtyr deacylase	145
647047416	304	37.11	9	298	20	308	3.0e-68	252	COG1560	Lauroyl/myristoyl acyltransferase	308
647047417	173	45.45	4	168	4	168	6.0e-48	183	COG1247	L-amino acid N-acyltransferase YncA	169
647047419	377	45.83	176	367	4	193	4.0e-52	198	COG0807	GTP cyclohydrolase II	193
647047420	199	31.71	72	190	33	152	1.0e-17	83.4	COG3402	Uncharacterized membrane protein YdbS, contains bPH2 (bacterial pleckstrin homology) domain	161
647047421	501	24.18	9	486	2	481	2.0e-38	154	COG3428	Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain	494
647047422	351	18.71	29	311	65	381	1.0e-16	81.2	COG1887	CDP-glycerol glycerophosphotransferase, TagB/SpsB family	388
647047423	274	20.82	9	267	1	265	6.0e-16	78.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
647047424	425	21.46	30	414	34	418	2.0e-17	83.7	COG3307	O-antigen ligase	424
647047425	573	26.77	9	515	9	500	1.0e-44	174	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
647047426	436	37.29	100	436	2	355	4.0e-72	265	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
647047427	307	54.64	1	301	2	302	6.0e-106	377	COG0223	Methionyl-tRNA formyltransferase	307
647047428	170	53.22	1	167	1	168	1.0e-57	215	COG0242	Peptide deformylase	168
647047432	157	50.32	5	157	1	157	4.0e-51	193	COG2922	Uncharacterized conserved protein Smg, DUF494 family	157
647047434	426	22.81	216	386	9	158	1.0e-08	55.1	COG1714	Uncharacterized membrane protein YckC, RDD family	172
647047436	830	48.81	3	583	1	561	0.0e+00	642	COG0550	DNA topoisomerase IA	570
647047437	187	39.89	7	186	16	195	3.0e-43	168	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
647047440	258	42.69	7	254	2	251	4.0e-47	181	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647047442	633	37.7	276	578	4	300	2.0e-62	234	COG0616	Periplasmic serine protease, ClpP class	317
647047443	458	34.01	14	456	12	451	2.0e-64	240	COG0534	Na+-driven multidrug efflux pump	455
647047447	740	47.32	5	739	1	730	0.0e+00	760	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
647047448	218	33.82	15	216	1	205	2.0e-30	125	COG0625	Glutathione S-transferase	211
647047449	276	20.56	9	162	6	178	4.0e-07	48.9	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
647047452	417	48.88	2	399	9	405	8.0e-115	407	COG1252	NADH dehydrogenase, FAD-containing subunit	405
647047453	177	43.26	1	177	29	206	2.0e-32	132	COG2860	Uncharacterized membrane protein YeiH	209
647047454	291	37.99	14	287	60	329	1.0e-66	247	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
647047455	241	60.99	8	229	1	223	2.0e-98	352	COG0692	Uracil DNA glycosylase	223
647047458	316	36.05	17	310	1	293	3.0e-61	228	COG2177	Cell division protein FtsX	297
647047459	228	57.4	3	225	1	223	2.0e-82	299	COG2884	ABC-type ATPase involved in cell division	223
647047461	493	39.18	1	480	21	495	6.0e-106	378	COG0513	Superfamily II DNA and RNA helicase	513
647047463	426	69.29	7	426	3	420	0.0e+00	692	COG1158	Transcription termination factor Rho	422
647047468	965	16.47	347	925	199	736	7.0e-15	76.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647047472	571	16.52	58	571	58	604	3.0e-48	187	COG1874	Beta-galactosidase GanA	673
647047475	497	34.46	1	495	3	498	9.0e-96	344	COG1070	Sugar (pentulose or hexulose) kinase	502
647047476	76	32.08	12	64	13	65	9.0e-07	45.3	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
647047480	526	24.94	28	443	29	452	7.0e-22	98.8	COG3846	Type IV secretory pathway, TrbL components	452
647047482	208	25.65	5	195	50	235	5.0e-16	78.2	COG5314	Conjugal transfer/entry exclusion protein	252
647047491	886	33.51	27	399	19	365	2.0e-63	238	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
647047493	704	40.4	1	690	2	693	0.0e+00	681	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
647047501	487	49.31	50	484	1	430	0.0e+00	593	COG3538	Meiotically up-regulated gene 157 (Mug157) protein (function unknown)	434
647047502	780	40.46	4	779	1	758	0.0e+00	781	COG3537	Putative alpha-1,2-mannosidase	768
647047503	582	21.74	1	581	1	610	3.0e-82	299	COG1874	Beta-galactosidase GanA	673
647047508	367	20.61	44	353	27	373	2.0e-24	106	COG4692	Predicted neuraminidase (sialidase)	381
647047509	236	47.84	3	233	8	239	1.0e-68	252	COG3142	Copper homeostasis protein CutC	241
647047510	281	38.24	1	271	45	307	1.0e-64	239	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
647047525	1042	18.86	284	848	38	656	3.0e-09	58	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
647047530	432	24.19	51	427	30	407	4.0e-35	142	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647047531	418	40.25	16	414	3	383	1.0e-103	370	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
647047532	296	26.21	7	291	8	264	2.0e-28	120	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
647047534	163	56.33	8	162	13	170	5.0e-43	167	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
647047535	473	19.68	30	464	3	424	7.0e-33	135	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
647047536	119	53.23	3	119	1	124	1.0e-33	135	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
647047538	157	53.21	1	156	1	154	5.0e-52	197	COG4807	Uncharacterized conserved protein YehS, DUF1456 family	155
647047539	869	38.6	19	868	26	845	0.0e+00	689	COG1643	HrpA-like RNA helicase	845
647047542	298	33.46	43	297	3	236	6.0e-45	174	COG4798	Predicted methyltransferase	238
647047543	323	45.99	5	319	4	312	5.0e-77	281	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
647047544	343	51.74	1	343	4	340	9.0e-110	390	COG2130	NADPH-dependent curcumin reductase CurA	340
647047549	142	53.57	5	142	4	143	3.0e-42	163	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
647047550	153	37.8	26	152	1	126	8.0e-13	66.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
647047552	364	50.55	1	363	6	367	5.0e-129	454	COG1485	Predicted ATPase	367
647047553	220	40.48	7	213	1	205	5.0e-54	204	COG2945	Alpha/beta superfamily hydrolase	210
647047556	330	42.59	11	327	1	293	3.0e-81	295	COG0523	GTPase, G3E family	323
647047559	572	39.83	26	572	193	788	1.0e-96	347	COG2374	Predicted extracellular nuclease	798
647047560	159	43.1	40	154	11	121	2.0e-15	75.1	COG3245	Cytochrome c5	126
647047563	545	21.18	8	387	1	393	1.0e-24	108	COG3182	Uncharacterized iron-regulated membrane protein	442
647047565	175	31.41	10	164	12	160	3.0e-17	81.6	COG5654	Uncharacterized conserved protein, contains RES domain	163
647047567	206	27.32	11	203	8	201	5.0e-10	57.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647047568	382	43.73	1	382	1	391	9.0e-91	327	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
647047569	536	46.08	12	536	1	526	0.0e+00	632	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
647047570	675	55.61	15	670	2	643	0.0e+00	791	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
647047572	886	28.43	17	208	42	220	7.0e-10	59.8	COG2114	Adenylate cyclase, class 3	227
647047573	356	39.29	173	336	12	179	7.0e-30	124	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
647047574	431	72.75	1	425	1	433	0.0e+00	643	COG2224	Isocitrate lyase	433
647047575	538	43.9	17	537	14	541	0.0e+00	501	COG2225	Malate synthase	545
647047576	318	35.74	13	301	2	288	5.0e-39	155	COG0583	DNA-binding transcriptional regulator, LysR family	297
647047578	419	29.5	1	399	1	381	1.0e-38	154	COG0475	Kef-type K+ transport system, membrane component KefB	397
647047579	115	32.74	13	115	14	126	2.0e-14	71.5	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
647047580	210	25.5	9	208	4	201	2.0e-11	62.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647047581	350	33.21	70	327	4	252	3.0e-37	149	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
647047583	722	47.08	42	720	1	681	0.0e+00	829	COG0339	Zn-dependent oligopeptidase	683
647047584	336	49.84	23	331	2	307	6.0e-81	294	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
647047587	164	29.8	14	163	21	170	3.0e-17	81.2	COG3184	Uncharacterized protein	183
647047588	272	33.19	42	255	78	288	3.0e-42	165	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
647047589	195	32.79	25	192	36	217	2.0e-28	119	COG4122	Predicted O-methyltransferase YrrM	219
647047590	557	45.57	1	528	4	514	0.0e+00	465	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
647047591	214	34.16	8	207	2	198	1.0e-31	130	COG3165	Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain	204
647047592	367	40.62	3	351	2	317	2.0e-88	319	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
647047596	336	28.61	1	324	1	304	7.0e-40	158	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647047597	550	29.16	1	499	7	483	2.0e-62	234	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
647047598	127	28.35	1	125	9	131	3.0e-15	74.3	COG0727	Fe-S-cluster containining protein	132
647047599	300	26.74	15	297	6	281	2.0e-19	90.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647047600	379	31.45	12	343	2	336	1.0e-46	180	COG3177	Fic family protein	348
647047601	338	27	3	338	1	322	1.0e-58	220	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
647047604	158	60	4	157	1	154	6.0e-58	216	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
647047608	448	50.22	1	448	4	456	1.0e-130	460	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
647047610	575	35.92	5	549	2	547	0.0e+00	470	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
647047612	341	54.88	7	334	3	329	6.0e-116	410	COG0240	Glycerol-3-phosphate dehydrogenase	329
647047613	170	55.4	19	157	11	149	2.0e-45	175	COG1952	Preprotein translocase subunit SecB	157
647047614	144	37.38	39	144	4	110	2.0e-17	81.9	COG0607	Rhodanese-related sulfurtransferase	110
647047617	269	25	1	226	2	219	7.0e-24	104	COG3306	Glycosyltransferase involved in LPS biosynthesis, GR25 family	255
647047618	258	27.87	11	250	2	243	2.0e-24	105	COG1587	Uroporphyrinogen-III synthase	248
647047619	313	19.94	4	312	37	360	3.0e-12	66.2	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
647047620	421	28.83	4	385	1	392	5.0e-58	219	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
647047622	431	30.89	10	431	2	391	4.0e-56	212	COG0183	Acetyl-CoA acetyltransferase	392
647047624	145	28.99	14	138	2	138	2.0e-09	55.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
647047626	215	43.98	48	205	18	178	9.0e-28	117	COG2032	Cu/Zn superoxide dismutase	179
647047627	200	34.02	4	189	1	179	2.0e-23	102	COG2032	Cu/Zn superoxide dismutase	179
647047628	475	50.65	8	468	5	451	0.0e+00	475	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
647047629	345	41.91	1	332	10	353	5.0e-88	318	COG3852	Signal transduction histidine kinase, nitrogen specific	363
647047630	463	58.13	58	462	3	403	7.0e-119	421	COG0004	Ammonia channel protein AmtB	409
647047631	114	75	3	114	1	112	3.0e-39	153	COG0347	Nitrogen regulatory protein PII	112
647047632	469	48.52	1	467	1	441	0.0e+00	510	COG0174	Glutamine synthetase	443
647047633	265	39.78	1	260	3	267	3.0e-53	201	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
647047634	269	20.14	37	173	6	140	2.0e-06	46.6	COG3187	Heat shock protein HslJ	142
647047637	203	36.18	1	199	23	174	1.0e-34	139	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
647047638	690	25.13	31	221	32	226	1.0e-08	55.4	COG3063	Tfp pilus assembly protein PilF	250
647047640	329	27.27	9	329	23	342	2.0e-28	120	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
647047641	299	25.1	59	292	1	245	8.0e-20	91.1	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
647047642	142	35	1	139	1	139	4.0e-24	103	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
647047644	190	28.57	11	178	10	182	4.0e-21	94.6	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
647047646	158	40.12	1	158	1	161	2.0e-35	141	COG2062	Phosphohistidine phosphatase SixA	163
647047647	210	26.95	1	209	2	256	1.0e-20	92.9	COG1192	Cellulose biosynthesis protein BcsQ	259
647047648	305	32.89	9	304	12	311	3.0e-28	119	COG0679	Predicted permease	311
647047651	1235	31.7	35	721	1	636	0.0e+00	544	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
647047654	278	42.75	27	278	20	270	1.0e-58	220	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
647047658	393	24.36	25	390	19	399	5.0e-33	135	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
647047659	490	34.88	5	274	17	297	2.0e-63	237	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
647047660	245	46.69	1	241	1	242	4.0e-71	261	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
647047662	401	37.82	20	257	45	282	9.0e-61	227	COG1398	Fatty-acid desaturase	289
647047663	281	40.25	13	248	24	256	6.0e-46	178	COG1119	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA	257
647047664	336	43.67	68	311	2	226	8.0e-55	207	COG2013	Uncharacterized conserved protein, AIM24 family	227
647047665	470	37.13	66	464	7	387	2.0e-87	316	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
647047668	425	44.1	3	355	1	343	2.0e-82	300	COG2951	Membrane-bound lytic murein transglycosylase B	343
647047670	737	36.19	3	737	16	719	0.0e+00	522	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
647047671	160	51.33	7	156	6	154	2.0e-34	138	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647047672	296	52.69	25	284	34	291	2.0e-91	329	COG3186	Phenylalanine-4-hydroxylase	291
647047676	218	23.75	1	159	1	151	7.0e-28	117	COG0698	Ribose 5-phosphate isomerase RpiB	151
647047677	251	38.19	5	249	1	251	2.0e-42	166	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647047678	284	48.75	6	284	2	278	1.0e-110	393	COG3717	5-keto 4-deoxyuronate isomerase	278
647047679	342	38.32	10	340	1	332	9.0e-71	260	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
647047680	527	27.87	30	526	4	549	9.0e-85	308	COG3507	Beta-xylosidase	549
647047682	428	48.55	48	426	3	379	2.0e-86	313	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
647047683	173	33.54	13	170	4	161	4.0e-18	84.2	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
647047684	332	32.73	1	330	1	328	7.0e-71	260	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
647047685	273	27.99	10	272	2	264	1.0e-33	136	COG3971	2-keto-4-pentenoate hydratase	264
647047686	359	24.84	27	331	6	306	6.0e-18	85.4	COG0657	Acetyl esterase/lipase	312
647047687	539	35.66	42	534	1	491	8.0e-103	368	COG2272	Carboxylesterase type B	491
647047688	382	24.76	60	366	14	304	2.0e-39	157	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
647047690	716	56.62	87	714	1	628	0.0e+00	765	COG0296	1,4-alpha-glucan branching enzyme	628
647047691	1116	34.51	26	530	1	505	2.0e-95	344	COG0366	Glycosidase	505
647047695	333	61.68	2	333	1	332	0.0e+00	464	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
647047697	1006	27.97	145	993	40	927	9.0e-56	212	COG5373	Uncharacterized membrane protein	931
647047700	391	55.25	1	389	2	393	0.0e+00	480	COG0126	3-phosphoglycerate kinase	395
647047701	214	30.59	1	214	2	218	4.0e-38	151	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
647047702	488	48.84	4	476	3	477	0.0e+00	557	COG0469	Pyruvate kinase	477
647047704	334	56.29	2	334	1	332	2.0e-127	449	COG3588	Fructose-bisphosphate aldolase class 1	332
647047705	179	49.71	1	175	3	176	1.0e-48	185	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
647047706	168	33.33	25	168	41	182	4.0e-18	84.3	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
647047708	319	55.3	3	300	1	300	4.0e-104	371	COG0031	Cysteine synthase	300
647047709	401	54.88	130	375	1	244	3.0e-80	292	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
647047710	327	30.59	1	301	1	297	8.0e-30	124	COG0583	DNA-binding transcriptional regulator, LysR family	297
647047713	398	22.19	91	398	20	330	9.0e-30	124	COG0642	Signal transduction histidine kinase	336
647047715	667	17.83	4	667	30	768	2.0e-26	115	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647047717	241	44.83	15	239	13	242	8.0e-61	227	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
647047718	568	40.91	4	552	8	504	0.0e+00	475	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
647047719	615	47.92	19	615	3	587	0.0e+00	564	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
647047720	302	35.53	7	302	17	261	2.0e-53	203	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
647047721	643	63.15	32	457	1	426	0.0e+00	645	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
647047722	356	30.94	1	340	5	365	2.0e-20	93.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
647047723	1041	40.77	2	1014	1	1007	0.0e+00	924	COG0841	Multidrug efflux pump subunit AcrB	1009
647047728	197	36.51	1	188	67	253	2.0e-36	145	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
647047730	180	27.68	3	172	1	177	5.0e-15	74.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
647047736	350	40.36	13	347	1	332	5.0e-75	274	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
647047737	472	18.64	57	453	4	396	4.0e-17	83	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
647047738	143	55.07	1	133	1	128	5.0e-36	143	COG1970	Large-conductance mechanosensitive channel	130
647047739	237	43.81	22	230	57	257	3.0e-56	211	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
647047742	131	37.35	48	130	26	103	6.0e-13	66.5	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
647047743	620	20.12	120	615	54	456	1.0e-28	121	COG0471	Di- and tricarboxylate transporter	461
647047744	252	43.61	23	246	1	227	1.0e-62	233	COG0220	tRNA G46 methylase TrmB	227
647047745	264	63.42	8	264	6	260	3.0e-101	361	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
647047746	66	48.48	1	66	3	68	2.0e-14	71	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
647047747	512	34.44	2	332	13	370	4.0e-60	226	COG3240	Phospholipase/lecithinase/hemolysin	370
647047756	111	71.29	10	110	2	102	1.0e-36	144	COG0051	Ribosomal protein S10	104
647047757	216	60.85	6	216	1	212	2.0e-74	272	COG0087	Ribosomal protein L3	218
647047758	201	41.43	1	201	2	211	1.0e-44	172	COG0088	Ribosomal protein L4	214
647047759	99	49.46	8	99	2	94	9.0e-21	91.8	COG0089	Ribosomal protein L23	94
647047760	275	60.87	1	275	1	275	7.0e-105	373	COG0090	Ribosomal protein L2	275
647047761	89	73.86	1	86	1	88	4.0e-33	132	COG0185	Ribosomal protein S19	93
647047762	113	65.14	2	110	8	116	8.0e-33	132	COG0091	Ribosomal protein L22	120
647047763	244	60.94	12	243	1	233	5.0e-80	290	COG0092	Ribosomal protein S3	233
647047764	137	64.71	1	134	2	137	1.0e-48	185	COG0197	Ribosomal protein L16/L10AE	146
647047765	61	53.7	4	57	6	59	2.0e-07	47.2	COG0255	Ribosomal protein L29	69
647047766	89	58.23	11	89	9	87	8.0e-22	95.3	COG0186	Ribosomal protein S17	87
647047767	122	74.59	1	122	1	122	1.0e-50	191	COG0093	Ribosomal protein L14	122
647047768	105	49.52	1	104	1	104	2.0e-20	90.7	COG0198	Ribosomal protein L24	104
647047769	180	64.97	4	180	3	179	2.0e-74	271	COG0094	Ribosomal protein L5	180
647047770	101	56.9	44	101	4	61	2.0e-14	70.6	COG0199	Ribosomal protein S14	61
647047771	132	56.82	1	131	1	131	7.0e-43	166	COG0096	Ribosomal protein S8	132
647047772	175	51.41	1	175	1	177	8.0e-56	209	COG0097	Ribosomal protein L6P/L9E	178
647047773	119	46.61	5	119	8	125	2.0e-25	107	COG0256	Ribosomal protein L18	125
647047774	180	54.49	1	177	1	178	1.0e-51	196	COG0098	Ribosomal protein S5	181
647047775	63	41.82	9	63	1	55	4.0e-09	52.8	COG1841	Ribosomal protein L30/L7E	55
647047776	147	47.33	3	147	1	150	2.0e-30	124	COG0200	Ribosomal protein L15	152
647047777	454	51.87	14	439	14	432	1.0e-120	427	COG0201	Preprotein translocase subunit SecY	436
647047778	118	62.18	1	118	1	119	3.0e-37	147	COG0099	Ribosomal protein S13	121
647047779	130	68.46	1	130	1	129	4.0e-46	176	COG0100	Ribosomal protein S11	129
647047780	208	55.29	1	208	1	205	3.0e-61	228	COG0522	Ribosomal protein S4 or related protein	205
647047781	332	54.43	8	322	1	313	6.0e-100	357	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
647047782	127	71.55	1	116	1	116	7.0e-46	175	COG0203	Ribosomal protein L17	116
647047783	172	38.46	1	167	5	168	1.0e-22	99.3	COG1495	Disulfide bond formation protein DsbB	170
647047784	707	18.9	1	707	21	768	2.0e-22	101	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647047786	450	51.38	1	436	4	439	0.0e+00	534	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
647047787	375	21.72	46	330	3	284	5.0e-14	72.2	COG0668	Small-conductance mechanosensitive channel	316
647047788	134	21.71	5	133	2	124	1.0e-05	42.4	COG3293	Transposase	124
647047789	266	40.87	8	257	9	258	4.0e-61	228	COG0300	Short-chain dehydrogenase	265
647047790	251	51.98	1	250	1	249	2.0e-77	282	COG0149	Triosephosphate isomerase	251
647047794	118	49.15	1	118	4	121	7.0e-29	119	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
647047795	184	65.85	21	184	5	168	9.0e-75	272	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
647047796	250	40.47	9	223	10	175	5.0e-44	171	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
647047797	435	56.64	14	435	4	398	0.0e+00	604	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
647047798	175	42.24	15	175	1	157	1.0e-48	186	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
647047799	444	57.14	11	433	1	424	0.0e+00	622	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
647047800	744	40.91	15	705	2	693	0.0e+00	641	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
647047801	363	46.87	25	358	11	331	3.0e-88	319	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
647047802	163	44.24	4	163	2	161	6.0e-42	163	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
647047803	227	44.77	9	180	1	166	3.0e-29	122	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
647047804	101	58.42	1	101	1	100	2.0e-21	94.4	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
647047805	719	40.03	10	713	1	606	0.0e+00	483	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
647047806	491	54.14	1	491	9	491	0.0e+00	530	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
647047807	487	44.7	13	484	3	472	3.0e-108	386	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
647047809	196	47.8	1	159	3	153	7.0e-42	163	COG0779	Ribosome maturation factor RimP	153
647047810	503	48.98	161	355	1	190	8.0e-51	195	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
647047813	656	57.62	155	656	3	507	0.0e+00	641	COG0532	Translation initiation factor IF-2, a GTPase	509
647047814	130	43.75	4	113	2	113	7.0e-26	109	COG0858	Ribosome-binding factor A	118
647047815	308	36.77	11	300	15	270	6.0e-64	237	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
647047816	86	60	2	86	5	89	2.0e-23	101	COG0184	Ribosomal protein S15P/S13E	89
647047817	704	63.88	1	695	2	692	0.0e+00	987	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
647047818	295	48.8	1	248	91	304	4.0e-41	161	COG4322	Uncharacterized protein	304
647047820	295	45.88	14	289	2	277	1.0e-77	283	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
647047821	89	25.29	1	87	1	60	1.0e-08	51.4	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
647047822	167	65.43	6	167	1	160	2.0e-57	214	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
647047824	349	50.74	1	331	33	366	1.0e-110	393	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
647047825	192	48.22	1	191	2	198	1.0e-59	222	COG0605	Superoxide dismutase	204
647047826	106	52.43	1	103	2	104	2.0e-41	160	COG0278	Glutaredoxin-related protein	105
647047829	199	41.12	1	194	5	201	3.0e-35	141	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
647047832	461	28.92	145	345	4	200	3.0e-37	149	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
647047833	157	33.11	1	149	16	166	2.0e-20	92	COG4970	Tfp pilus assembly protein FimT	181
647047834	158	26.88	8	156	4	160	2.0e-16	78.9	COG4967	Tfp pilus assembly protein PilV	162
647047837	1292	25.38	407	1291	204	1035	1.0e-69	258	COG3419	Tfp pilus assembly protein, tip-associated adhesin PilY1	1036
647047838	126	45.45	1	126	10	139	2.0e-25	107	COG4968	Tfp pilus assembly protein PilE	139
647047840	180	32.77	7	178	5	178	4.0e-25	107	COG4970	Tfp pilus assembly protein FimT	181
647047841	673	64.64	1	673	1	661	0.0e+00	1079	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
647047844	557	30.98	6	545	25	560	1.0e-88	321	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
647047846	344	33.47	5	246	6	232	2.0e-32	133	COG3736	Type IV secretory pathway, component VirB8	239
647047847	255	22.87	8	250	3	236	2.0e-21	95.8	COG3504	Type IV secretory pathway, VirB9 components	265
647047848	389	24.65	37	386	2	354	9.0e-38	151	COG2948	Type IV secretory pathway, VirB10 components	360
647047849	349	29.18	28	331	18	297	6.0e-56	211	COG0630	Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase	312
647047856	103	38.95	4	96	8	100	2.0e-08	50.6	COG3702	Type IV secretory pathway, VirB3 components	105
647047862	196	38.46	95	196	20	123	4.0e-11	61.6	COG3755	Uncharacterized conserved protein YecT, DUF1311 family	127
647047867	299	33.79	77	295	51	231	9.0e-38	150	COG0860	N-acetylmuramoyl-L-alanine amidase	231
647047868	302	32.11	1	293	1	280	3.0e-50	192	COG1469	GTP cyclohydrolase FolE2	289
647047872	455	36.36	33	444	2	412	1.0e-81	297	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
647047873	161	46.88	1	160	1	158	4.0e-45	173	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
647047874	271	56.44	11	271	3	265	3.0e-92	331	COG0413	Ketopantoate hydroxymethyltransferase	268
647047875	280	53.55	2	280	1	282	2.0e-99	355	COG0414	Panthothenate synthetase	285
647047876	126	58.4	2	126	1	125	4.0e-45	173	COG0853	Aspartate 1-decarboxylase	126
647047877	504	44.28	40	496	1	446	5.0e-125	441	COG0166	Glucose-6-phosphate isomerase	446
647047879	208	33.12	1	156	1	157	3.0e-24	105	COG4185	Predicted ABC-type ATPase	187
647047882	888	31.65	103	528	1	391	7.0e-70	259	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
647047884	520	30.1	8	516	2	519	2.0e-67	250	COG4146	Uncharacterized membrane permease YidK, sodium:solute symporter family	571
647047885	614	45.45	345	597	2	252	2.0e-72	267	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
647047887	188	54.89	1	184	4	182	1.0e-58	219	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
647047888	361	22.13	120	361	85	336	5.0e-16	78.7	COG0642	Signal transduction histidine kinase	336
647047891	421	44.06	17	420	1	359	3.0e-126	445	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
647047892	243	25.82	30	235	18	230	3.0e-07	49	COG0671	Membrane-associated phospholipid phosphatase	232
647047893	427	22.73	73	421	63	391	6.0e-08	52.5	COG2814	Predicted arabinose efflux permease, MFS family	394
647047894	234	57.64	6	234	2	230	1.0e-82	299	COG1794	Aspartate/glutamate racemase	230
647047895	303	26.47	152	282	5	140	6.0e-07	48.3	COG2510	Uncharacterized membrane protein	140
647047896	350	33.72	10	350	2	290	4.0e-73	268	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
647047897	351	45.9	44	342	2	294	4.0e-84	304	COG0167	Dihydroorotate dehydrogenase	310
647047901	510	36.31	30	498	12	471	4.0e-109	388	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647047916	251	49.79	2	244	1	243	2.0e-82	298	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
647047919	400	66.5	1	398	1	394	0.0e+00	580	COG0027	Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	394
647047922	53	46.94	2	50	4	52	3.0e-09	53.5	COG4877	Uncharacterized protein	63
647047926	224	39.13	1	220	56	284	6.0e-43	167	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
647047927	134	38.05	29	134	9	121	4.0e-06	44	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
647047929	213	49.06	2	213	1	209	3.0e-54	204	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
647047930	398	26.32	52	383	36	364	3.0e-33	136	COG4585	Signal transduction histidine kinase	365
647047932	198	53.94	1	164	6	167	8.0e-55	206	COG3818	Predicted acetyltransferase, GNAT superfamily	167
647047933	248	36.02	13	247	2	217	9.0e-47	180	COG0850	Septum formation inhibitor MinC	219
647047934	269	65.8	1	269	1	269	7.0e-119	419	COG2894	Septum formation inhibitor-activating ATPase MinD	272
647047935	85	50.6	1	82	1	83	1.0e-21	94.5	COG0851	Septum formation topological specificity factor MinE	88
647047937	429	28.21	117	421	21	327	2.0e-27	117	COG0642	Signal transduction histidine kinase	336
647047938	274	40.97	37	258	1	226	2.0e-48	185	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647047939	577	26.65	9	522	2	500	5.0e-39	156	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
647047940	254	53.18	22	240	24	241	6.0e-52	197	COG3907	Membrane-associated enzyme, PAP2 (acid phosphatase) superfamily	249
647047941	555	36.95	18	549	3	544	0.0e+00	504	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
647047944	407	20.7	19	389	32	391	2.0e-19	90.7	COG2814	Predicted arabinose efflux permease, MFS family	394
647047947	718	37.5	18	718	3	703	0.0e+00	590	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
647047948	449	24.23	57	380	5	288	3.0e-12	66.5	COG1566	Multidrug resistance efflux pump	352
647047952	977	59.8	454	944	5	496	0.0e+00	722	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
647047953	284	41.97	12	277	6	268	1.0e-64	239	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
647047954	702	58.32	30	528	4	496	0.0e+00	707	COG0753	Catalase	496
647047962	241	32.23	116	235	6	126	2.0e-19	89.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647047972	895	64.42	4	893	1	885	0.0e+00	1364	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
647047980	143	24.62	10	134	13	142	5.0e-12	63.9	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
647047981	139	20.18	2	109	1	109	5.0e-09	53.9	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
647047983	207	26.64	1	204	3	216	3.0e-22	98.3	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
647047985	239	32.89	4	227	5	228	6.0e-32	130	COG1802	DNA-binding transcriptional regulator, GntR family	230
647047987	306	29.63	1	285	2	298	2.0e-37	149	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
647047988	289	37.55	23	285	7	282	8.0e-40	157	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
647047996	273	45	9	266	2	259	2.0e-62	232	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
647047998	810	20.48	64	810	2	768	1.0e-22	102	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647048000	361	35.24	1	348	1	309	4.0e-35	142	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
647048004	249	43.96	57	237	11	192	3.0e-44	172	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
647048005	196	25.62	9	196	4	205	3.0e-19	88.5	COG0778	Nitroreductase	207
647048006	332	34.06	22	330	4	326	2.0e-70	259	COG3660	Mitochondrial fission protein ELM1	329
647048016	969	40.11	21	923	1	919	0.0e+00	671	COG1391	Glutamine synthetase adenylyltransferase	963
647048018	306	35.06	39	298	19	277	3.0e-41	162	COG3386	Sugar lactone lactonase YvrE	307
647048022	357	67.24	1	350	1	351	0.0e+00	567	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
647048028	322	56.56	1	321	1	343	0.0e+00	479	COG1089	GDP-D-mannose dehydratase	345
647048029	306	29.6	6	301	1	315	6.0e-43	168	COG1088	dTDP-D-glucose 4,6-dehydratase	340
647048031	418	44	3	248	1	249	8.0e-77	281	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
647048032	263	29.92	1	263	6	263	8.0e-33	134	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
647048035	394	56.96	10	393	1	392	0.0e+00	497	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
647048036	456	47.1	3	310	1	300	4.0e-99	355	COG0031	Cysteine synthase	300
647048042	377	53.76	1	358	5	363	1.0e-126	446	COG5008	Tfp pilus assembly protein, ATPase PilU	375
647048043	220	33.03	5	218	1	209	1.0e-25	109	COG0625	Glutathione S-transferase	211
647048044	329	25.23	4	327	1	266	1.0e-29	123	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
647048045	460	44.01	1	451	29	482	7.0e-119	421	COG0513	Superfamily II DNA and RNA helicase	513
647048046	117	45.24	1	117	3	126	1.0e-31	128	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
647048048	224	42.47	4	222	3	218	1.0e-59	223	COG0132	Dethiobiotin synthetase	223
647048049	160	55.62	1	160	2	161	7.0e-60	223	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
647048051	216	40.74	1	215	1	216	5.0e-40	157	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
647048052	359	49	2	344	1	349	1.0e-89	323	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
647048054	171	33.54	12	167	1	147	1.0e-34	139	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
647048059	674	56.26	1	674	8	683	0.0e+00	876	COG0339	Zn-dependent oligopeptidase	683
647048060	367	29.43	14	325	2	297	3.0e-74	272	COG0031	Cysteine synthase	300
647048062	605	27.25	18	415	1	344	1.0e-54	208	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
647048063	348	43.97	1	348	1	321	1.0e-76	280	COG3667	Uncharacterized protein involved in copper resistance	321
647048064	174	27.03	24	168	3	137	1.0e-11	62.9	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
647048070	609	51.31	1	609	1	597	0.0e+00	797	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
647048071	423	23.41	74	351	46	341	2.0e-18	87.3	COG1566	Multidrug resistance efflux pump	352
647048072	239	50.44	1	224	1	226	6.0e-78	283	COG1136	ABC-type lipoprotein export system, ATPase component	226
647048073	433	20.5	126	431	119	417	3.0e-14	73.6	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
647048074	410	20.47	14	410	1	419	3.0e-10	60.2	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
647048075	447	41.67	1	445	4	457	1.0e-110	393	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
647048077	454	56.02	4	454	2	458	0.0e+00	607	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
647048080	189	38.16	37	111	24	99	4.0e-12	64.6	COG1605	Chorismate mutase	101
647048081	140	47.41	1	134	1	135	2.0e-30	124	COG0355	FoF1-type ATP synthase, epsilon subunit	135
647048082	468	73.57	1	467	1	468	0.0e+00	830	COG0055	FoF1-type ATP synthase, beta subunit	468
647048084	287	51.75	5	287	1	286	2.0e-100	358	COG0224	FoF1-type ATP synthase, gamma subunit	287
647048085	515	66.02	4	515	2	502	0.0e+00	813	COG0056	FoF1-type ATP synthase, alpha subunit	504
647048086	175	38.98	1	173	1	177	4.0e-35	140	COG0712	FoF1-type ATP synthase, delta subunit	178
647048087	156	43.05	6	156	8	158	6.0e-15	73.8	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
647048089	266	36.74	3	266	4	246	7.0e-48	184	COG0356	FoF1-type ATP synthase, membrane subunit a	246
647048093	607	51.41	133	591	2	454	0.0e+00	488	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
647048095	586	43.72	126	586	3	403	6.0e-96	345	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
647048096	186	35.26	22	185	1	164	1.0e-20	93.1	COG3663	G:T/U-mismatch repair DNA glycosylase	169
647048097	228	33.92	65	228	46	213	5.0e-31	127	COG3047	Outer membrane protein W	213
647048104	266	55.6	1	266	1	268	8.0e-96	343	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
647048105	231	55.66	11	231	2	222	2.0e-67	249	COG2011	ABC-type methionine transport system, permease component	222
647048106	335	57.57	1	333	1	337	9.0e-128	450	COG1135	ABC-type methionine transport system, ATPase component	339
647048108	161	53.09	1	161	4	165	2.0e-44	171	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
647048111	578	26.51	91	436	2	334	2.0e-34	141	COG0642	Signal transduction histidine kinase	336
647048113	186	62.05	16	181	21	186	2.0e-64	237	COG3310	Uncharacterized protein	196
647048114	268	36.08	15	262	3	251	2.0e-37	149	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647048115	226	36.57	10	223	1	216	3.0e-37	148	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
647048116	237	39.26	1	231	3	242	1.0e-52	199	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
647048117	355	31.33	51	350	8	300	1.0e-50	193	COG2813	16S rRNA G1207 methylase RsmC	300
647048120	426	32.26	1	423	7	396	1.0e-75	277	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
647048123	660	34.04	180	510	17	336	8.0e-42	165	COG0642	Signal transduction histidine kinase	336
647048128	366	51.38	1	356	2	360	2.0e-119	422	COG0787	Alanine racemase	360
647048129	429	33.33	1	422	5	387	5.0e-48	185	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647048130	159	45.45	4	157	2	154	8.0e-34	136	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647048133	154	56.67	15	133	7	126	6.0e-49	186	COG0229	Peptide methionine sulfoxide reductase MsrB	140
647048136	284	39.64	1	280	3	261	8.0e-68	250	COG1291	Flagellar motor component MotA	266
647048137	385	28.47	9	279	1	243	1.0e-41	164	COG1360	Flagellar motor protein MotB	244
647048140	266	30.87	40	266	3	227	2.0e-23	103	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647048146	1668	50.43	33	1667	11	1592	0.0e+00	1844	COG2902	NAD-specific glutamate dehydrogenase	1592
647048147	258	20.9	2	201	1	201	1.0e-08	54.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647048148	401	32.16	1	337	42	369	4.0e-21	96.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
647048149	1056	49.42	1	1029	2	1008	0.0e+00	990	COG0841	Multidrug efflux pump subunit AcrB	1009
647048163	331	41.39	3	326	1	331	6.0e-80	291	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
647048164	838	44.7	275	830	3	565	0.0e+00	585	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
647048165	318	42.63	6	317	3	309	2.0e-75	276	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
647048166	580	60.53	242	580	1	340	6.0e-96	345	COG1299	Phosphotransferase system, fructose-specific IIC component	343
647048167	425	30.43	35	421	55	435	3.0e-52	199	COG3659	Carbohydrate-selective porin OprB	439
647048174	322	40	6	314	1	304	4.0e-74	271	COG0341	Preprotein translocase subunit SecF	305
647048175	614	45.31	100	608	17	501	4.0e-117	415	COG0342	Preprotein translocase subunit SecD	506
647048176	117	43.75	21	116	2	97	7.0e-26	109	COG1862	Preprotein translocase subunit YajC	97
647048177	381	58.71	6	378	1	371	0.0e+00	534	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
647048178	356	54.31	1	344	1	342	0.0e+00	467	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
647048179	143	37.32	1	139	4	145	8.0e-20	89.7	COG1522	DNA-binding transcriptional regulator, Lrp family	154
647048181	498	28.99	85	494	25	404	5.0e-39	156	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
647048184	373	23.83	34	366	13	360	8.0e-10	58.5	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)	364
647048185	851	16.19	273	849	187	766	2.0e-19	91.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647048186	210	59.33	1	208	2	210	2.0e-71	261	COG0035	Uracil phosphoribosyltransferase	210
647048191	579	45.27	19	564	5	531	0.0e+00	568	COG0405	Gamma-glutamyltranspeptidase	539
647048194	168	62.82	5	160	1	156	4.0e-62	230	COG0669	Phosphopantetheine adenylyltransferase	159
647048195	206	42.25	15	193	1	187	1.0e-49	189	COG0742	16S rRNA G966 N2-methylase RsmD	187
647048197	634	59.02	4	634	1	623	0.0e+00	814	COG0326	Molecular chaperone, HSP90 family	623
647048203	96	41.38	1	87	1	83	2.0e-18	83.8	COG1343	CRISPR/Cas system-associated endoribonuclease Cas2	89
647048204	346	35.88	7	345	3	327	5.0e-67	248	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
647048205	210	24.19	6	191	15	190	1.0e-20	93.2	COG1468	CRISPR/Cas system-associated exonuclease Cas4, RecB family	190
647048206	292	29.63	1	291	1	275	3.0e-39	155	COG3649	CRISPR/Cas system type I-B associated protein Csh2, Cas7 group, RAMP superfamily	283
647048210	812	21.04	146	685	62	614	2.0e-42	167	COG1203	CRISPR/Cas system-associated endonuclease/helicase Cas3	733
647048211	566	19.93	21	562	25	584	2.0e-13	70.8	COG4715	Uncharacterized conserved protein, contains Zn finger domain	587
647048212	743	71.56	1	742	2	743	0.0e+00	1224	COG2838	Monomeric isocitrate dehydrogenase	744
647048214	315	28.96	4	293	1	297	3.0e-26	112	COG0583	DNA-binding transcriptional regulator, LysR family	297
647048215	579	36.51	14	577	6	568	2.0e-122	433	COG4579	Isocitrate dehydrogenase kinase/phosphatase	578
647048219	328	40.71	6	319	17	354	6.0e-75	274	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
647048220	1364	33.12	570	876	42	335	2.0e-41	165	COG0642	Signal transduction histidine kinase	336
647048221	434	38.52	12	429	1	411	3.0e-116	411	COG2733	Uncharacterized membrane-anchored protein YjiN, DUF445 family	415
647048225	450	46.03	17	450	8	445	0.0e+00	506	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
647048228	281	47.55	7	271	1	264	3.0e-72	265	COG1526	Formate dehydrogenase assembly factor FdhD	266
647048229	782	22.38	46	759	41	759	1.0e-95	344	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
647048233	426	22.41	73	426	63	390	2.0e-07	51	COG2814	Predicted arabinose efflux permease, MFS family	394
647048234	418	32.99	38	416	49	432	2.0e-61	230	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
647048235	438	27.02	38	419	1	387	1.0e-46	180	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647048236	459	34.99	11	458	2	443	6.0e-102	364	COG0174	Glutamine synthetase	443
647048237	251	43.72	5	247	4	243	3.0e-65	241	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
647048238	461	36.48	18	460	5	443	1.0e-115	410	COG0174	Glutamine synthetase	443
647048239	455	42.29	6	454	2	449	0.0e+00	495	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
647048240	371	44.86	3	371	6	363	9.0e-93	333	COG0687	Spermidine/putrescine-binding periplasmic protein	363
647048244	497	35.74	14	496	1	453	4.0e-44	172	COG1538	Outer membrane protein TolC	457
647048245	377	49.04	16	377	2	352	2.0e-119	422	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
647048246	303	50.51	5	301	1	285	4.0e-68	251	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
647048247	281	47.41	1	269	3	266	2.0e-58	219	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
647048248	454	39.47	1	453	14	467	4.0e-117	415	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
647048249	333	38.99	18	333	7	322	1.0e-69	256	COG0598	Mg2+ and Co2+ transporter CorA	322
647048251	292	52.94	2	289	1	287	2.0e-106	379	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
647048253	161	50	8	160	3	153	1.0e-43	168	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
647048255	329	50.76	1	322	8	336	3.0e-108	385	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
647048257	484	52.14	37	477	4	435	0.0e+00	558	COG0621	tRNA A37 methylthiotransferase MiaB	437
647048258	226	34.12	20	219	1	210	3.0e-25	108	COG0625	Glutathione S-transferase	211
647048264	191	31.28	1	179	21	170	2.0e-28	119	COG0723	Rieske Fe-S protein	177
647048265	419	49.62	7	399	2	372	7.0e-95	341	COG1290	Cytochrome b subunit of the bc complex	381
647048266	247	36.8	9	247	2	250	3.0e-58	218	COG2857	Cytochrome c1	250
647048267	211	31.84	11	197	1	200	3.0e-26	111	COG0625	Glutathione S-transferase	211
647048268	139	49.67	1	139	5	155	1.0e-42	165	COG2969	Stringent starvation protein B	155
647048272	255	45.42	1	238	1	234	1.0e-61	230	COG3967	Short-chain dehydrogenase involved in D-alanine esterification of teichoic acids	245
647048273	1454	37.2	2	844	12	788	0.0e+00	678	COG1201	Lhr-like helicase	814
647048274	203	47.21	1	192	4	197	3.0e-51	195	COG2094	3-methyladenine DNA glycosylase Mpg	200
647048275	552	34.15	131	501	3	408	1.0e-40	161	COG0840	Methyl-accepting chemotaxis protein	408
647048276	161	34.23	4	152	13	157	7.0e-30	123	COG0835	Chemotaxis signal transduction protein	165
647048277	353	32.96	171	346	4	181	4.0e-23	102	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
647048280	133	25.76	1	128	2	128	4.0e-13	66.9	COG2916	DNA-binding protein H-NS	128
647048282	876	49.82	589	865	10	287	4.0e-82	299	COG3285	Eukaryotic-type DNA primase	299
647048285	594	33.44	304	592	36	311	9.0e-45	175	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
647048287	420	39.71	42	409	40	450	5.0e-79	288	COG3946	Type IV secretory pathway, VirJ component	456
647048289	445	48.53	5	445	2	438	4.0e-123	435	COG1570	Exonuclease VII, large subunit	440
647048290	355	48.54	13	352	2	337	4.0e-96	345	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
647048291	495	44.88	214	491	2	283	4.0e-61	229	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
647048292	166	44.52	8	150	5	149	3.0e-34	138	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
647048293	577	33.46	292	551	8	231	1.0e-49	191	COG0860	N-acetylmuramoyl-L-alanine amidase	231
647048297	311	33.21	33	309	6	260	4.0e-66	244	COG3358	Uncharacterized conserved protein, DUF1684 family	262
647048298	324	30.74	49	314	31	298	9.0e-42	164	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
647048299	213	42.77	25	181	8	172	9.0e-41	160	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
647048300	240	42.21	1	235	9	249	5.0e-44	171	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647048302	292	34.14	4	286	20	295	3.0e-40	159	COG0501	Zn-dependent protease with chaperone function	302
647048303	689	32.64	442	682	1	241	5.0e-42	166	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
647048304	393	50.87	2	390	1	400	0.0e+00	478	COG2081	Predicted flavoprotein YhiN	408
647048305	182	40.7	1	172	1	172	8.0e-50	189	COG4681	Uncharacterized conserved protein YaeQ, suppresses RfaH defect	181
647048307	69	58.21	4	69	1	67	6.0e-21	92.5	COG1278	Cold shock protein, CspA family	67
647048308	232	33.64	1	216	1	201	9.0e-26	110	COG0625	Glutathione S-transferase	211
647048310	324	24.5	41	320	17	309	7.0e-22	98.1	COG0657	Acetyl esterase/lipase	312
647048311	518	43.8	20	518	11	488	0.0e+00	564	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
647048312	186	51.57	20	178	10	168	1.0e-41	162	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
647048313	458	38.58	1	457	28	483	7.0e-105	374	COG0513	Superfamily II DNA and RNA helicase	513
647048314	630	44.09	1	525	1	527	0.0e+00	527	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
647048318	146	46.72	6	137	17	150	2.0e-28	118	COG4290	Guanyl-specific ribonuclease Sa	152
647048319	203	62.62	1	203	2	203	9.0e-78	282	COG0605	Superoxide dismutase	204
647048320	277	45.63	3	264	2	259	3.0e-68	251	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
647048321	254	48.76	3	244	1	234	2.0e-66	245	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
647048322	288	23.93	1	276	25	290	4.0e-23	101	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
647048324	323	28.19	4	291	2	280	6.0e-16	78.8	COG3547	Transposase	303
647048327	188	45.04	1	131	1	131	2.0e-36	145	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
647048329	449	39.67	14	425	3	413	6.0e-85	308	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
647048330	239	56.38	1	239	1	242	2.0e-85	308	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
647048331	230	38.57	14	221	5	213	1.0e-40	159	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
647048337	162	33.33	1	130	1	129	3.0e-17	81.1	COG3871	General stress protein 26 (function unknown)	145
647048341	449	37.53	4	439	3	428	2.0e-112	399	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
647048342	99	54.88	12	93	8	89	3.0e-23	100	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
647048344	224	50.83	105	224	1	120	2.0e-28	119	COG1734	RNA polymerase-binding transcription factor DksA	120
647048345	416	20.82	71	409	65	391	6.0e-09	55.6	COG2814	Predicted arabinose efflux permease, MFS family	394
647048346	145	42.25	5	144	1	142	1.0e-37	148	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
647048347	476	51.9	4	475	1	463	0.0e+00	629	COG0215	Cysteinyl-tRNA synthetase	464
647048350	343	39.64	1	333	4	308	3.0e-91	329	COG0078	Ornithine carbamoyltransferase	310
647048351	412	38.86	16	412	2	400	2.0e-114	406	COG0137	Argininosuccinate synthase	403
647048353	366	25.81	3	363	10	404	1.0e-34	141	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
647048354	447	37.36	40	293	1	265	2.0e-62	233	COG0548	Acetylglutamate kinase	265
647048355	220	24.34	29	210	1	187	1.0e-14	73.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
647048356	316	37.28	4	316	1	343	2.0e-86	312	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
647048357	431	36.46	1	429	1	455	4.0e-105	375	COG0165	Argininosuccinate lyase	459
647048358	121	22.12	8	111	18	118	6.0e-10	56.6	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
647048360	384	49.6	14	384	1	369	2.0e-116	412	COG0263	Glutamate 5-kinase	369
647048361	414	55.9	1	414	3	417	0.0e+00	528	COG0014	Gamma-glutamyl phosphate reductase	417
647048363	637	32.18	37	636	9	560	1.0e-114	407	COG2936	Predicted acyl esterase	563
647048368	570	40.22	34	559	3	527	6.0e-110	391	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
647048369	561	37.68	13	554	11	550	6.0e-101	361	COG4987	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components	573
647048370	204	36.59	108	189	7	88	2.0e-17	82.6	COG3326	Uncharacterized membrane protein YsdA, DUF1294 family	94
647048371	400	41.06	1	397	8	365	1.0e-109	390	COG2021	Homoserine acetyltransferase	368
647048372	337	27.01	11	217	77	286	1.0e-22	100	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
647048373	144	50	4	143	5	143	2.0e-36	145	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
647048374	200	26.36	41	166	1	127	5.0e-11	61.5	COG0526	Thiol-disulfide isomerase or thioredoxin	127
647048375	645	54.84	1	644	1	648	0.0e+00	623	COG1138	Cytochrome c biogenesis factor	648
647048376	156	52.78	1	143	1	144	3.0e-46	177	COG2332	Cytochrome c-type biogenesis protein CcmE	153
647048378	250	38.93	1	243	31	274	3.0e-41	162	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
647048379	231	49.32	11	231	1	221	5.0e-37	148	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
647048383	328	38.81	1	328	58	388	2.0e-77	282	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
647048386	270	34.32	8	268	3	267	3.0e-35	142	COG0388	Predicted amidohydrolase	274
647048387	284	46.25	31	282	7	258	1.0e-75	276	COG3823	Glutamine cyclotransferase	262
647048389	527	43.7	27	273	2	247	2.0e-64	240	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
647048390	400	47.03	1	184	4	184	2.0e-46	179	COG1386	Chromosome segregation and condensation protein ScpB	184
647048391	301	44.3	44	274	1	237	2.0e-48	186	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
647048392	99	50	1	98	1	92	5.0e-18	82.6	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
647048393	89	43.18	1	88	2	87	7.0e-20	88.9	COG0271	Stress-induced morphogen (activity unknown)	90
647048395	340	42.64	6	335	1	331	6.0e-76	278	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
647048396	992	11.75	81	676	1	552	2.0e-07	52.6	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
647048399	453	30.16	1	411	7	433	2.0e-48	186	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
647048400	293	40.41	1	291	5	291	3.0e-61	228	COG1175	ABC-type sugar transport system, permease component	295
647048401	278	47.45	9	277	8	281	1.0e-59	223	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
647048404	303	22.76	40	293	2	258	9.0e-20	91.2	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
647048405	410	42.53	17	409	1	388	5.0e-105	374	COG1916	Pheromone shutdown protein TraB, contains GTxH motif (function unknown)	388
647048406	145	42.07	2	144	1	144	3.0e-35	141	COG1247	L-amino acid N-acyltransferase YncA	169
647048407	294	37.37	6	291	3	273	8.0e-54	204	COG0388	Predicted amidohydrolase	274
647048409	344	49.56	3	340	13	346	3.0e-112	398	COG2957	Agmatine/peptidylarginine deiminase	346
647048413	227	52.73	6	224	5	220	2.0e-67	248	COG0283	Cytidylate kinase	222
647048414	561	57.64	1	550	1	541	0.0e+00	603	COG0539	Ribosomal protein S1	541
647048415	103	51.11	1	90	2	90	2.0e-29	120	COG0776	Bacterial nucleoid DNA-binding protein	94
647048417	392	44.79	11	392	6	389	0.0e+00	473	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
647048418	322	25.25	1	283	4	303	1.0e-31	130	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
647048419	635	43	16	620	1	588	0.0e+00	623	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
647048420	297	58.28	4	292	3	290	2.0e-112	398	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
647048422	106	71.74	13	104	12	102	1.0e-31	127	COG3492	Uncharacterized protein	104
647048423	297	57.91	13	290	1	276	6.0e-108	384	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
647048424	485	29.68	256	474	1	170	7.0e-33	135	COG0516	IMP dehydrogenase/GMP reductase	170
647048425	521	68.65	203	521	1	315	0.0e+00	547	COG0519	GMP synthase, PP-ATPase domain/subunit	315
647048426	402	22.14	102	370	17	281	8.0e-10	58.3	COG4974	Site-specific recombinase XerD	300
647048433	84	50.65	1	76	1	76	5.0e-14	69.3	COG4691	Plasmid stability protein	80
647048434	139	29.93	1	137	3	131	1.0e-19	88.7	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
647048435	266	32.48	10	243	9	231	4.0e-30	125	COG5314	Conjugal transfer/entry exclusion protein	252
647048437	544	26.81	7	427	8	436	4.0e-40	159	COG3846	Type IV secretory pathway, TrbL components	452
647048443	391	27.02	1	356	1	352	4.0e-47	182	COG2865	Predicted transcriptional regulator, contains HTH domain	467
647048445	797	34.02	13	781	53	872	0.0e+00	486	COG3002	Uncharacterized conserved protein YbcC, UPF0753/DUF2309 family	880
647048447	296	29.17	4	288	1	285	9.0e-27	114	COG0583	DNA-binding transcriptional regulator, LysR family	297
647048448	303	31.54	5	298	2	291	1.0e-33	137	COG0583	DNA-binding transcriptional regulator, LysR family	297
647048450	260	32.08	5	255	1	249	2.0e-28	119	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647048451	372	50.58	22	367	6	333	2.0e-80	292	COG2855	Uncharacterized membrane protein YadS	334
647048456	199	46.8	2	197	9	211	8.0e-43	167	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
647048459	140	40	6	110	17	121	8.0e-18	83	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
647048460	218	16.99	13	209	1	205	5.0e-18	84.9	COG1335	Nicotinamidase-related amidase	205
647048461	145	30.61	1	145	1	142	1.0e-06	46.1	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
647048462	654	42.88	37	572	1	533	0.0e+00	466	COG1574	Predicted amidohydrolase YtcJ	535
647048463	602	24.5	112	459	46	382	1.0e-15	78.7	COG2814	Predicted arabinose efflux permease, MFS family	394
647048465	274	27.86	9	274	8	281	1.0e-31	130	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647048467	444	51.18	23	442	1	412	2.0e-88	320	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
647048468	155	43.44	29	149	1	122	4.0e-28	117	COG1321	Mn-dependent transcriptional regulator, DtxR family	154
647048469	174	53.95	13	164	1	151	5.0e-47	180	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
647048470	194	65.5	9	179	6	176	4.0e-77	280	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
647048471	328	36.1	46	313	38	314	8.0e-43	167	COG0668	Small-conductance mechanosensitive channel	316
647048472	792	49.56	1	791	1	740	0.0e+00	734	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
647048473	273	49.1	2	273	1	273	2.0e-84	306	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
647048474	169	32.17	8	150	4	144	2.0e-41	161	COG3151	Uncharacterized protein YqiB, DUF1249 family	147
647048475	162	25.18	1	139	4	131	5.0e-08	50.8	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
647048476	252	30.96	1	193	6	202	5.0e-32	131	COG0300	Short-chain dehydrogenase	265
647048477	204	32.51	3	204	1	177	1.0e-28	119	COG1183	Phosphatidylserine synthase	234
647048479	358	29.75	41	355	82	400	2.0e-59	223	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
647048480	65	42.19	3	65	2	65	3.0e-11	60.2	COG1983	Phage shock protein PspC (stress-responsive transcriptional regulator)	70
647048482	403	21.84	26	397	2	375	8.0e-33	135	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
647048484	787	57.54	4	787	4	779	0.0e+00	975	COG2183	Transcriptional accessory protein Tex/SPT6	780
647048485	946	34.35	500	792	53	336	8.0e-44	172	COG0642	Signal transduction histidine kinase	336
647048487	126	29.91	4	115	3	119	7.0e-06	42.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
647048492	153	50.53	51	144	9	102	9.0e-16	76.2	COG2863	Cytochrome c553	121
647048495	371	34.06	9	353	6	372	5.0e-26	112	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
647048496	1170	31.42	24	1141	1	1009	0.0e+00	724	COG0841	Multidrug efflux pump subunit AcrB	1009
647048497	1028	28.04	2	1001	1	1008	0.0e+00	651	COG0841	Multidrug efflux pump subunit AcrB	1009
647048502	638	38.78	9	602	4	571	0.0e+00	564	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
647048506	305	48.86	1	305	1	299	4.0e-97	347	COG0837	Glucokinase	320
647048507	476	48.53	1	467	6	475	0.0e+00	573	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
647048510	365	52.26	1	354	1	338	9.0e-122	430	COG3839	ABC-type sugar transport system, ATPase component	338
647048511	268	32.57	3	253	29	283	2.0e-35	142	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
647048513	131	28.46	4	129	1	129	2.0e-13	68.4	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
647048514	128	35.04	8	124	1	117	1.0e-16	78.3	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
647048515	596	52.32	6	579	2	561	0.0e+00	645	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
647048516	260	53.19	25	259	1	231	2.0e-84	305	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
647048517	101	36.9	17	100	6	89	2.0e-18	84.1	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
647048519	416	42.93	4	416	1	408	3.0e-108	385	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
647048520	244	49.55	18	238	1	222	7.0e-73	267	COG1136	ABC-type lipoprotein export system, ATPase component	226
647048521	354	17.19	7	306	4	308	3.0e-10	59.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647048522	802	35.55	495	785	2	293	1.0e-59	225	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
647048523	220	29.7	1	201	12	213	2.0e-33	135	COG0811	Biopolymer transport protein ExbB/TolQ	216
647048524	154	30.94	1	139	3	137	1.0e-27	116	COG0848	Biopolymer transport protein ExbD	137
647048525	589	38.57	14	586	1	567	1.0e-123	437	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
647048526	345	42.74	4	338	1	334	2.0e-84	306	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
647048528	259	54.84	7	254	2	240	2.0e-85	309	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
647048529	154	41.45	1	152	3	139	1.0e-31	129	COG0394	Protein-tyrosine-phosphatase	139
647048531	618	49.67	9	604	3	581	0.0e+00	632	COG0322	Excinuclease UvrABC, nuclease subunit	581
647048532	210	42.56	1	195	10	192	5.0e-29	121	COG0558	Phosphatidylglycerophosphate synthase	192
647048537	430	42.79	13	427	11	429	0.0e+00	465	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
647048538	419	32.37	4	410	1	408	2.0e-94	339	COG2081	Predicted flavoprotein YhiN	408
647048541	253	44.63	2	240	5	240	9.0e-76	276	COG1054	Predicted sulfurtransferase	308
647048542	215	40.76	3	211	1	211	2.0e-46	178	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
647048545	969	55.21	1	487	4	487	0.0e+00	567	COG1530	Ribonuclease G or E	487
647048546	328	39.47	19	317	4	289	1.0e-66	247	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
647048549	118	48.98	20	117	4	101	2.0e-28	117	COG2154	Pterin-4a-carbinolamine dehydratase	101
647048550	199	43.33	103	191	4	93	1.0e-23	103	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
647048559	235	43.29	2	229	4	227	2.0e-45	175	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647048560	330	33.62	16	329	10	363	2.0e-50	192	COG1858	Cytochrome c peroxidase	364
647048563	316	23.31	1	294	6	296	5.0e-16	78.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
647048564	342	30.46	8	337	7	341	3.0e-15	76.7	COG3515	Predicted component of the type VI protein secretion system	346
647048568	240	34.27	1	233	4	251	6.0e-36	144	COG0631	Serine/threonine protein phosphatase PrpC	262
647048569	217	30.43	1	195	1	205	3.0e-14	72.1	COG3913	Uncharacterized protein	227
647048571	1018	33.91	2	998	3	1026	0.0e+00	554	COG3523	Type VI protein secretion system component VasK	1188
647048572	438	38.67	22	277	7	259	2.0e-48	187	COG3455	Type VI protein secretion system component VasF	262
647048573	445	50	1	445	1	446	0.0e+00	465	COG3522	Predicted component of the type VI protein secretion system	446
647048575	346	24.21	6	346	1	312	5.0e-21	95.5	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
647048577	645	39.29	3	538	13	539	1.0e-128	454	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
647048581	314	41.53	1	313	1	309	2.0e-70	259	COG3520	Predicted component of the type VI protein secretion system	335
647048582	625	44.09	1	625	1	621	0.0e+00	592	COG3519	Type VI protein secretion system component VasA	621
647048583	167	39.02	4	166	1	157	5.0e-21	94.3	COG3518	Predicted component of the type VI protein secretion system	157
647048584	277	36.82	11	266	9	265	3.0e-47	182	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion	273
647048585	167	28.95	1	149	1	151	2.0e-22	98.8	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
647048586	500	58.12	1	499	1	495	0.0e+00	738	COG3517	Predicted component of the type VI protein secretion system	495
647048587	227	53.66	64	226	2	165	1.0e-55	209	COG3516	Predicted component of the type VI protein secretion system	169
647048589	443	31.06	14	430	12	397	7.0e-72	264	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
647048598	881	19.56	362	879	77	577	2.0e-17	85.5	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
647048599	371	27.94	29	363	16	353	1.0e-23	104	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
647048600	1030	43.3	1	1023	1	1026	0.0e+00	1048	COG3696	Cu/Ag efflux pump CusA	1027
647048601	494	35.54	38	490	5	456	2.0e-44	174	COG1538	Outer membrane protein TolC	457
647048603	203	50.99	2	203	1	202	3.0e-61	228	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
647048604	770	26.94	179	770	27	577	4.0e-34	140	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
647048608	625	39.61	368	622	3	256	2.0e-62	234	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
647048609	196	52.97	9	193	5	189	2.0e-67	248	COG3506	Regulation of enolase protein 1 (function unknown), concanavalin A-like superfamily	189
647048612	169	35.54	1	163	3	167	7.0e-37	146	COG3685	Ferritin-like metal-binding protein YciE	167
647048616	331	46.19	1	210	1	210	5.0e-47	181	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
647048618	186	31.18	1	175	2	183	2.0e-22	99.2	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
647048619	417	39.04	1	408	6	404	2.0e-74	273	COG0303	Molybdopterin biosynthesis enzyme	404
647048621	329	39.85	7	262	2	261	4.0e-78	285	COG0708	Exonuclease III	261
647048624	389	35.37	1	389	1	350	4.0e-68	251	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
647048632	380	57.6	116	361	8	254	1.0e-76	280	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
647048634	406	43.21	4	406	3	403	7.0e-101	361	COG0303	Molybdopterin biosynthesis enzyme	404
647048636	465	48.76	1	442	2	444	0.0e+00	539	COG1160	Predicted GTPases	444
647048637	405	25.93	24	390	5	359	8.0e-39	154	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
647048638	212	34.62	3	203	1	207	2.0e-34	139	COG2976	Putative negative regulator of RcsB-dependent stress response	207
647048639	286	24.63	14	234	2	273	6.0e-23	101	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
647048640	262	43.44	32	252	20	240	2.0e-47	182	COG3063	Tfp pilus assembly protein PilF	250
647048641	401	53.44	22	383	1	349	3.0e-127	448	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
647048642	141	62.22	2	136	1	135	3.0e-54	203	COG0105	Nucleoside diphosphate kinase	135
647048643	210	19.9	1	205	5	201	3.0e-07	48.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647048644	790	34	7	305	3	293	9.0e-62	232	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
647048645	401	41.56	6	399	2	390	2.0e-87	316	COG0183	Acetyl-CoA acetyltransferase	392
647048646	154	38.1	27	152	1	126	1.0e-20	92.5	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
647048647	436	56.57	3	428	13	436	0.0e+00	589	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
647048650	209	35.44	1	205	6	208	3.0e-34	138	COG2834	Outer membrane lipoprotein-sorting protein	211
647048653	785	35.28	24	783	82	856	0.0e+00	488	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
647048654	322	49.37	9	322	1	304	1.0e-91	329	COG0492	Thioredoxin reductase	305
647048655	387	47.79	11	386	3	384	2.0e-126	446	COG3146	Predicted N-acyltransferase	387
647048657	242	49.77	9	229	2	220	8.0e-75	273	COG2360	Leu/Phe-tRNA-protein transferase	221
647048658	78	70.83	7	78	1	72	8.0e-25	105	COG0361	Translation initiation factor IF-1	75
647048660	760	45.9	1	746	1	782	0.0e+00	853	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
647048661	106	53.06	9	106	10	107	2.0e-31	127	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
647048663	152	26.81	9	143	8	143	4.0e-09	54.3	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
647048664	378	55.96	1	359	1	355	0.0e+00	469	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
647048665	200	34.85	4	198	7	203	2.0e-50	192	COG2915	Regulator of phage lambda lysogenization HflD, binds to CII and stimulates its degradation	207
647048672	533	43.92	142	396	4	256	1.0e-68	254	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
647048677	314	37.34	6	161	3	156	2.0e-28	120	COG0835	Chemotaxis signal transduction protein	165
647048678	133	34.59	1	132	1	132	2.0e-23	101	COG1815	Flagellar basal body rod protein FlgB	133
647048679	135	45.99	1	135	1	137	6.0e-35	139	COG1558	Flagellar basal body rod protein FlgC	137
647048680	221	35.16	4	217	1	218	1.0e-29	122	COG1843	Flagellar hook assembly protein FlgD	222
647048681	407	43.5	1	407	3	422	8.0e-83	301	COG1749	Flagellar hook protein FlgE	423
647048682	251	45.06	1	250	1	251	1.0e-60	226	COG4787	Flagellar basal body rod protein FlgF	251
647048684	261	53.21	1	261	1	264	2.0e-77	282	COG4786	Flagellar basal body rod protein FlgG	265
647048685	230	36.21	1	225	1	229	7.0e-43	167	COG2063	Flagellar basal body L-ring protein FlgH	230
647048686	353	55.97	2	353	17	365	1.0e-110	393	COG1706	Flagellar basal body P-ring protein FlgI	365
647048687	392	45	196	355	26	179	1.0e-34	140	COG1705	Flagellum-specific peptidoglycan hydrolase FlgJ	201
647048690	401	20.85	4	401	2	358	3.0e-29	123	COG1344	Flagellin and related hook-associated protein FlgL	360
647048691	399	37.78	3	399	1	360	2.0e-43	170	COG1344	Flagellin and related hook-associated protein FlgL	360
647048693	441	29.08	1	441	4	479	5.0e-36	145	COG1345	Flagellar capping protein FliD	483
647048694	137	37.59	1	133	1	127	3.0e-24	103	COG1516	Flagellin-specific chaperone FliS	132
647048697	210	42.72	1	205	1	206	2.0e-46	179	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
647048698	467	41.72	1	458	1	443	7.0e-93	334	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
647048700	494	41.02	1	491	2	462	6.0e-113	401	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
647048701	369	38.38	1	363	1	367	2.0e-84	306	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
647048705	254	36.61	8	247	1	251	6.0e-34	138	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647048706	245	38.49	9	242	1	249	4.0e-32	131	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647048707	214	31.21	58	213	41	179	2.0e-14	73	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
647048708	381	19.54	1	381	1	362	8.0e-27	114	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
647048712	1183	25	574	795	2	218	4.0e-12	67.8	COG1216	Glycosyltransferase, GT2 family	305
647048714	123	33.33	19	123	2	105	5.0e-14	70	COG1677	Flagellar hook-basal body complex protein FliE	105
647048715	574	33.39	7	573	2	545	6.0e-96	345	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
647048716	329	47.87	2	328	12	339	8.0e-86	310	COG1536	Flagellar motor switch protein FliG	339
647048717	206	24.76	15	205	27	231	6.0e-18	84.3	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
647048718	458	55.25	19	454	4	439	0.0e+00	553	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
647048722	148	34.67	1	148	4	151	1.0e-16	79.2	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
647048724	186	40.78	9	183	6	184	1.0e-28	119	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
647048728	723	45.77	3	652	1	654	0.0e+00	606	COG0210	Superfamily I DNA or RNA helicase	655
647048729	466	31.14	12	459	4	459	9.0e-70	257	COG4529	Uncharacterized NAD(P)/FAD-binding protein YdhS	474
647048731	472	34.52	45	472	1	438	1.0e-65	244	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
647048733	55	50	4	53	1	50	2.0e-09	54.1	COG0267	Ribosomal protein L33	50
647048734	78	64.94	1	76	1	77	6.0e-20	89.2	COG0227	Ribosomal protein L28	77
647048736	1078	49.76	16	1068	1	1021	0.0e+00	1220	COG3696	Cu/Ag efflux pump CusA	1027
647048739	330	21.5	3	309	96	387	4.0e-12	65.9	COG3144	Flagellar hook-length control protein FliK	417
647048740	209	26.06	45	209	3	159	7.0e-19	87.6	COG1580	Flagellar basal body-associated protein FliL	159
647048741	337	43.99	4	317	2	316	1.0e-92	333	COG1868	Flagellar motor switch protein FliM	332
647048743	135	34.68	13	135	9	132	6.0e-17	80	COG3190	Flagellar biogenesis protein FliO	137
647048744	281	46	30	279	8	248	4.0e-65	241	COG1338	Flagellar biosynthetic protein FliP	248
647048746	89	39.33	1	89	1	89	3.0e-11	60.2	COG1987	Flagellar biosynthesis protein FliQ	89
647048747	263	36.86	7	261	1	253	1.0e-34	140	COG1684	Flagellar biosynthesis protein FliR	258
647048749	944	44.38	757	931	1	178	6.0e-40	159	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
647048750	973	44.44	788	964	2	179	8.0e-40	159	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
647048751	695	34.1	82	677	38	640	1.0e-92	334	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
647048752	376	43.53	2	362	1	363	3.0e-108	385	COG1377	Flagellar biosynthesis protein FlhB	363
647048754	593	52.2	1	588	66	650	0.0e+00	706	COG1298	Flagellar biosynthesis pathway, component FlhA	696
647048756	561	31.06	261	550	117	402	2.0e-55	210	COG1419	Flagellar biosynthesis GTPase FlhF	407
647048757	294	35.93	26	291	2	262	2.0e-52	199	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
647048758	255	38.03	12	243	16	246	5.0e-52	197	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
647048760	208	28.1	35	207	7	216	8.0e-18	83.9	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
647048771	423	32.35	149	415	99	364	3.0e-14	73.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
647048772	423	25.52	98	423	121	456	1.0e-15	78.3	COG1538	Outer membrane protein TolC	457
647048774	605	40.75	25	589	1	588	0.0e+00	520	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
647048775	212	44.71	14	211	5	212	3.0e-52	198	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
647048777	198	36.46	20	197	39	217	2.0e-28	118	COG2091	Phosphopantetheinyl transferase	223
647048780	145	25.89	22	132	4	113	7.0e-17	80.1	COG3791	Uncharacterized conserved protein	133
647048781	259	50	1	255	1	260	7.0e-84	303	COG0708	Exonuclease III	261
647048782	381	26.86	85	376	1	307	1.0e-33	137	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
647048786	575	55.13	32	567	1	529	0.0e+00	508	COG4147	Na+(or H+)/acetate symporter ActP	529
647048787	105	42.57	5	105	2	102	5.0e-26	109	COG3162	Uncharacterized membrane protein, DUF485 family	102
647048789	647	42.93	66	623	1	525	0.0e+00	658	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
647048790	222	37.07	4	207	3	206	9.0e-44	170	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
647048793	196	20.39	45	183	6	153	4.0e-06	45.2	COG1225	Peroxiredoxin	157
647048796	333	28.31	1	323	1	307	2.0e-47	182	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
647048797	290	33.82	4	277	10	278	2.0e-47	183	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
647048798	256	36.43	12	255	2	251	3.0e-40	158	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
647048799	285	46.38	10	279	1	264	2.0e-75	275	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
647048801	439	25.94	2	424	1	368	1.0e-50	194	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
647048802	119	30.61	1	98	1	93	6.0e-07	46.4	COG3254	L-rhamnose mutarotase	105
647048803	433	43.75	12	426	5	412	2.0e-88	319	COG0738	Fucose permease	422
647048804	249	27.87	11	248	1	244	1.0e-31	129	COG1414	DNA-binding transcriptional regulator, IclR family	246
647048806	194	44.27	1	192	1	190	1.0e-42	166	COG1971	Putative Mn2+ efflux pump MntP	190
647048807	1150	25.7	5	453	2	447	3.0e-56	214	COG0591	Na+/proline symporter	493
647048811	460	36.44	6	460	1	461	1.0e-98	354	COG2211	Na+/melibiose symporter or related transporter	467
647048812	194	43.4	20	178	1	159	9.0e-44	170	COG3265	Gluconate kinase	161
647048816	156	25.69	8	144	1	143	4.0e-06	44.4	COG0757	3-dehydroquinate dehydratase	146
647048821	1284	26.71	10	1284	2	1278	0.0e+00	583	COG2911	Autotransporter translocation and assembly factor TamB	1278
647048822	584	30.2	1	584	16	594	3.0e-115	409	COG0729	Outer membrane translocation and assembly module TamA	594
647048829	731	45.9	1	730	1	690	0.0e+00	752	COG0751	Glycyl-tRNA synthetase, beta subunit	691
647048830	302	77.29	8	302	4	297	0.0e+00	547	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
647048831	604	46.48	106	602	14	500	0.0e+00	506	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
647048841	250	35.92	3	207	1	195	4.0e-41	161	COG0518	GMP synthase - Glutamine amidotransferase domain	198
647048843	251	46.72	7	247	4	247	2.0e-54	205	COG0805	Sec-independent protein secretion pathway component TatC	255
647048844	208	37.21	1	86	1	86	1.0e-15	76.2	COG1826	Sec-independent protein translocase protein TatA	94
647048845	75	35.44	1	75	1	79	8.0e-13	65.4	COG1826	Sec-independent protein translocase protein TatA	94
647048846	358	42.73	61	284	1	227	6.0e-64	238	COG2930	Lipid-binding SYLF domain	227
647048847	318	42.24	2	318	1	317	2.0e-92	332	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
647048848	286	28.15	21	283	19	282	2.0e-13	70.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
647048851	261	27.04	21	253	3	223	3.0e-35	142	COG1451	Predicted metal-dependent hydrolase	223
647048852	301	43.71	1	300	1	301	6.0e-99	354	COG2974	DNA recombination-dependent growth factor C	303
647048853	305	35.57	29	277	1	245	2.0e-52	199	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
647048854	445	57.01	11	443	4	438	0.0e+00	589	COG2115	Xylose isomerase	438
647048855	402	38.81	60	393	1	332	5.0e-75	275	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
647048856	724	56.74	25	696	2	674	0.0e+00	876	COG3661	Alpha-glucuronidase	684
647048858	419	32.27	32	401	29	368	1.0e-65	243	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
647048859	566	35.05	35	557	2	530	5.0e-99	355	COG3507	Beta-xylosidase	549
647048860	902	34.25	49	443	35	387	3.0e-60	227	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
647048861	487	43.99	15	472	1	461	2.0e-121	429	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
647048862	377	46.45	11	373	3	361	2.0e-100	359	COG4748	Uncharacterized protein	365
647048867	52	68.29	2	42	3	43	3.0e-08	50.1	COG4338	Uncharacterized protein	54
647048870	333	20.39	44	279	82	372	5.0e-08	52.2	COG3055	N-acetylneuraminic acid mutarotase	381
647048871	337	17.91	110	310	2	199	6.0e-07	48.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647048874	148	25.78	12	137	42	162	1.0e-08	52.7	COG4731	Uncharacterized conserved protein, DUF2147 family	162
647048875	324	32.98	40	314	4	260	1.0e-33	137	COG3386	Sugar lactone lactonase YvrE	307
647048877	407	31.23	24	402	2	342	1.0e-64	241	COG3693	Endo-1,4-beta-xylanase, GH35 family	345
647048886	472	40.64	8	470	3	459	0.0e+00	525	COG1904	Glucuronate isomerase	463
647048887	325	25.92	3	325	1	345	1.0e-48	187	COG3693	Endo-1,4-beta-xylanase, GH35 family	345
647048888	412	24.94	15	411	32	417	2.0e-24	107	COG2223	Nitrate/nitrite transporter NarK	417
647048891	495	31.59	1	493	2	460	4.0e-87	315	COG2211	Na+/melibiose symporter or related transporter	467
647048893	177	25.71	1	175	1	172	1.0e-18	86.2	COG3040	Bacterial lipocalin	174
647048898	372	30	47	370	1	325	2.0e-48	186	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
647048899	889	40.84	71	876	27	805	0.0e+00	866	COG2937	Glycerol-3-phosphate O-acyltransferase	810
647048902	350	44.12	11	345	1	332	1.0e-80	293	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
647048906	243	43.75	1	238	1	238	3.0e-51	195	COG0284	Orotidine-5'-phosphate decarboxylase	240
647048907	362	35.34	113	359	43	269	6.0e-48	185	COG2503	Predicted secreted acid phosphatase	274
647048909	222	46.05	10	217	5	215	3.0e-50	191	COG3132	Uncharacterized conserved protein YceH, UPF0502 family	215
647048911	184	35.03	11	162	5	160	5.0e-17	80.8	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
647048913	658	44.43	3	640	2	655	0.0e+00	567	COG0210	Superfamily I DNA or RNA helicase	655
647048914	209	46.63	1	192	3	194	9.0e-67	246	COG1435	Thymidine kinase	201
647048916	414	21.03	138	402	69	333	1.0e-18	87.5	COG0642	Signal transduction histidine kinase	336
647048917	533	53.26	1	530	1	534	0.0e+00	712	COG3131	Periplasmic glucans biosynthesis protein	534
647048920	333	52.66	7	320	23	340	2.0e-114	406	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
647048923	148	56.08	1	147	1	148	2.0e-37	148	COG1610	Uncharacterized conserved protein YqeY	148
647048924	320	32.22	22	279	21	287	4.0e-32	131	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
647048925	581	39.62	3	581	1	566	2.0e-124	439	COG0358	DNA primase (bacterial type)	568
647048926	349	37.42	17	342	1	313	3.0e-63	235	COG0385	Predicted Na+-dependent transporter	319
647048928	298	45.27	1	296	14	302	2.0e-74	272	COG0109	Polyprenyltransferase (heme O synthase)	304
647048929	387	26.02	4	387	12	316	7.0e-33	135	COG1612	Heme A synthase	323
647048931	240	28.51	15	240	21	245	2.0e-15	76.1	COG3346	Cytochrome oxidase assembly protein ShyY1	252
647048933	291	37.66	53	291	1	206	8.0e-38	150	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
647048934	198	43.2	14	177	14	177	5.0e-40	157	COG3175	Cytochrome c oxidase assembly protein Cox11	195
647048936	534	52.61	11	522	1	517	0.0e+00	543	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
647048937	312	33.08	31	287	16	245	3.0e-52	199	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
647048938	179	27.78	39	174	20	162	2.0e-11	62.6	COG5488	Uncharacterized membrane protein	164
647048939	1066	59.17	464	1066	5	593	0.0e+00	769	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
647048940	271	53.85	1	271	1	273	2.0e-94	338	COG0266	Formamidopyrimidine-DNA glycosylase	273
647048947	403	40.94	6	401	5	401	6.0e-106	377	COG0162	Tyrosyl-tRNA synthetase	401
647048949	472	33.47	193	429	22	265	8.0e-39	155	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
647048951	377	55.53	8	377	3	370	3.0e-106	378	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
647048955	266	43.43	1	265	1	260	5.0e-78	284	COG0708	Exonuclease III	261
647048956	219	39.81	5	213	3	201	2.0e-46	178	COG0461	Orotate phosphoribosyltransferase	201
647048958	265	44.19	1	255	1	257	1.0e-60	226	COG1192	Cellulose biosynthesis protein BcsQ	259
647048959	309	37.16	42	300	1	240	5.0e-32	131	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
647048962	321	33.43	1	319	1	314	1.0e-54	207	COG0451	Nucleoside-diphosphate-sugar epimerase	314
647048963	240	23.74	2	216	1	210	3.0e-17	82.1	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
647048964	113	43.43	10	107	12	108	4.0e-25	106	COG3952	Uncharacterized N-terminal domain of lipid-A-disaccharide synthase	113
647048966	782	38.26	326	775	10	461	1.0e-105	377	COG1109	Phosphomannomutase	464
647048967	155	46.9	11	155	6	148	2.0e-46	178	COG0756	dUTPase	148
647048968	423	50.84	10	422	2	392	3.0e-113	402	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
647048969	213	46.95	1	213	1	213	1.0e-66	245	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
647048971	562	39.93	1	562	3	577	0.0e+00	551	COG0018	Arginyl-tRNA synthetase	577
647048975	251	52.48	2	241	6	246	1.0e-77	282	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
647048979	446	23.13	14	423	4	397	1.0e-28	120	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
647048980	628	56.1	1	625	22	652	0.0e+00	879	COG1166	Arginine decarboxylase (spermidine biosynthesis)	652
647048981	285	40.21	3	285	1	282	3.0e-77	281	COG0421	Spermidine synthase	282
647048988	112	69.64	1	112	1	112	2.0e-38	151	COG0347	Nitrogen regulatory protein PII	112
647048989	92	47.31	1	92	10	102	2.0e-18	83.9	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
647048990	506	60.25	16	498	2	489	0.0e+00	596	COG0606	Predicted ATPase with chaperone activity	490
647048991	185	44.94	23	178	25	174	9.0e-42	163	COG3040	Bacterial lipocalin	174
647048993	520	39.16	1	518	3	520	0.0e+00	476	COG4943	Environmental sensor c-di-GMP phosphodiesterase, contains periplasmic CSS-motif sensor and cytoplasmic EAL domain	524
647048994	373	21.43	13	370	10	341	2.0e-31	130	COG3239	Fatty acid desaturase	343
647048995	358	30.8	45	300	8	266	7.0e-38	151	COG1018	Ferredoxin-NADP reductase	266
647048996	215	20.4	11	211	4	201	8.0e-06	44.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
647049007	295	52.68	3	295	1	296	1.0e-99	356	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
647049009	478	45.38	40	383	13	342	3.0e-68	252	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
647049014	413	28.49	77	413	19	351	4.0e-37	149	COG0628	Predicted PurR-regulated permease PerM	355
647049015	245	31.6	4	229	3	228	2.0e-30	125	COG1011	FMN phosphatase YigB, HAD superfamily	229
647049016	456	38.41	31	455	34	485	9.0e-119	420	COG0260	Leucyl aminopeptidase	485
647049017	250	29.92	8	250	8	256	1.0e-12	66.6	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
647049018	138	33.59	1	122	46	173	3.0e-16	77.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
647049020	180	33.89	1	177	2	181	5.0e-29	120	COG3038	Cytochrome b561	181
647049022	200	40.67	2	200	1	209	5.0e-46	177	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
647049023	425	27.12	66	406	14	365	6.0e-38	152	COG4585	Signal transduction histidine kinase	365
647049024	409	23.23	16	279	3	273	6.0e-19	88.9	COG1566	Multidrug resistance efflux pump	352
647049025	229	52.89	4	227	1	225	2.0e-79	288	COG1136	ABC-type lipoprotein export system, ATPase component	226
647049026	386	16.87	4	385	7	407	9.0e-17	81.5	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
647049027	450	21.8	82	448	26	406	1.0e-19	91.9	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
647049029	302	45.55	6	297	2	291	9.0e-70	257	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
647049030	279	22.78	1	279	12	292	7.0e-06	44.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
647049031	559	26.67	126	554	5	433	9.0e-50	192	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
647049033	314	23.02	1	249	4	233	2.0e-17	83.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
647049034	429	40.5	1	313	4	314	2.0e-85	310	COG0180	Tryptophanyl-tRNA synthetase	314
647049035	69	38.46	1	65	3	67	3.0e-07	46.8	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
647049038	286	35.15	3	285	19	284	6.0e-48	184	COG0010	Arginase family enzyme	305
647049039	150	25.71	41	145	17	119	4.0e-07	47.5	COG2018	Predicted regulator of Ras-like GTPase activity, Roadblock/LC7/MglB family	119
647049042	180	35.12	6	173	11	176	2.0e-23	102	COG2229	Signal recognition particle receptor subunit beta, a GTPase	187
647049044	227	41.67	8	200	2	205	5.0e-43	167	COG0125	Thymidylate kinase	208
647049048	242	29.6	4	236	3	248	3.0e-34	138	COG1521	Pantothenate kinase type III	251
647049049	326	38.91	91	326	2	238	6.0e-46	178	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
647049052	265	39.44	11	258	5	251	5.0e-55	207	COG3228	Mlc titration factor MtfA, regulates ptsG expression	266
647049053	394	31.57	1	385	7	406	3.0e-44	172	COG4102	Uncharacterized conserved protein, DUF1501 family	418
647049055	533	33.1	127	533	115	496	2.0e-55	210	COG5267	Uncharacterized conserved protein, DUF1800 family	496
647049056	471	25.74	176	468	33	328	4.0e-32	132	COG0642	Signal transduction histidine kinase	336
647049057	227	46.72	1	223	1	228	1.0e-60	226	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
647049059	334	38.67	13	304	12	301	3.0e-78	285	COG0042	tRNA-dihydrouridine synthase	323
647049064	501	53.7	17	481	12	484	0.0e+00	627	COG0753	Catalase	496
647049067	711	29.02	40	710	12	639	5.0e-103	369	COG1199	Rad3-related DNA helicase	654
647049071	283	44.77	1	274	4	279	2.0e-71	262	COG0169	Shikimate 5-dehydrogenase	283
647049073	844	31.29	368	844	32	587	8.0e-85	308	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
