gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
650738123	397	29.35	113	386	3	258	5.0e-42	165	COG1192	Cellulose biosynthesis protein BcsQ	259
650738124	346	26.27	77	308	6	233	6.0e-17	81.9	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
650738125	375	20.86	67	338	20	260	1.0e-10	61.4	COG4974	Site-specific recombinase XerD	300
650738127	396	37.05	1	385	2	382	1.0e-97	350	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
650738136	92	31.91	1	92	2	93	7.0e-08	48.9	COG3668	Plasmid stabilization system protein ParE	98
650738141	546	39.38	86	531	7	454	2.0e-109	390	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
650738143	137	33.63	3	114	2	114	2.0e-18	84.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
650738148	812	40.94	2	404	5	361	3.0e-90	327	COG4951	Uncharacterized protein	361
650738154	198	22.99	36	121	34	120	2.0e-07	49.4	COG0789	DNA-binding transcriptional regulator, MerR family	124
650738155	240	31.82	10	227	5	219	4.0e-22	98.4	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
650738156	217	33.51	15	203	11	201	2.0e-21	96.1	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
650738157	346	31	5	329	2	303	1.0e-27	117	COG3547	Transposase	303
650738158	478	20.59	34	232	8	211	7.0e-03	35.9	COG0671	Membrane-associated phospholipid phosphatase	232
650738159	225	48.7	1	224	1	229	4.0e-60	224	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650738160	447	36.54	142	440	34	325	8.0e-41	161	COG0642	Signal transduction histidine kinase	336
650738161	457	23.33	21	448	1	442	2.0e-14	74	COG1538	Outer membrane protein TolC	457
650738163	1033	31.43	1	1028	1	1025	0.0e+00	611	COG3696	Cu/Ag efflux pump CusA	1027
650738165	423	30.52	25	391	18	358	2.0e-47	183	COG3328	Transposase (or an inactivated derivative)	379
650738167	221	37.61	116	220	1	107	3.0e-12	65.3	COG0607	Rhodanese-related sulfurtransferase	110
650738168	243	28.76	15	213	26	252	9.0e-13	67.6	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650738169	416	21.45	40	405	50	430	2.0e-09	57.1	COG2271	Sugar phosphate permease	448
650738170	247	34.92	2	247	55	345	1.0e-37	150	COG1566	Multidrug resistance efflux pump	352
650738174	249	28.98	7	246	7	230	3.0e-32	132	COG2243	Precorrin-2 methylase	234
650738175	242	44.87	1	234	2	231	2.0e-53	202	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
650738176	445	48.28	13	441	1	435	0.0e+00	468	COG1797	Cobyrinic acid a,c-diamide synthase	451
650738177	261	54.98	1	249	3	252	1.0e-92	332	COG2875	Precorrin-4 methylase	254
650738179	405	44.86	225	405	3	186	2.0e-43	170	COG2242	Precorrin-6B methylase 2	187
650738180	248	43.55	1	240	3	248	2.0e-55	208	COG2099	Precorrin-6x reductase	257
650738181	265	48.18	1	246	1	246	1.0e-76	279	COG1010	Precorrin-3B methylase	249
650738182	245	41.91	3	241	1	234	1.0e-56	213	COG2243	Precorrin-2 methylase	234
650738183	209	50	3	205	2	203	6.0e-51	193	COG2082	Precorrin isomerase	210
650738184	382	26.5	1	364	27	460	4.0e-31	129	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
650738186	344	35.48	7	337	1	314	3.0e-69	255	COG0523	GTPase, G3E family	323
650738187	120	43.09	4	120	19	141	2.0e-22	97.7	COG5469	Predicted metal-binding protein	143
650738188	205	56.28	7	205	2	198	1.0e-69	255	COG2109	ATP:corrinoid adenosyltransferase	198
650738189	481	52.57	1	481	1	485	0.0e+00	566	COG1492	Cobyric acid synthase	486
650738190	529	28.77	1	320	5	349	7.0e-43	168	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
650738191	313	46.71	1	313	3	315	9.0e-69	254	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
650738194	195	32.54	6	163	2	170	7.0e-19	87.2	COG0406	Broad specificity phosphatase PhoE	208
650738195	166	52.87	1	166	1	174	1.0e-52	199	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
650738196	342	44.44	14	340	2	334	4.0e-69	255	COG2038	NaMN:DMB phosphoribosyltransferase	347
650738197	251	45.61	14	251	6	242	1.0e-25	110	COG0368	Cobalamin synthase	246
650738201	224	19.86	1	142	3	148	1.0e-06	47	COG0629	Single-stranded DNA-binding protein	167
650738205	93	60.67	1	89	1	89	4.0e-24	102	COG5606	Predicted DNA-binding protein, XRE-type HTH domain	91
650738208	96	39.02	7	88	7	88	3.0e-09	53.4	COG4453	Uncharacterized conserved protein, DUF1778 family	95
650738210	163	38.95	5	163	29	200	3.0e-23	101	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650738215	377	29.03	5	376	2	340	6.0e-50	191	COG0673	Predicted dehydrogenase	342
650738216	387	30.95	5	338	2	312	7.0e-43	168	COG0673	Predicted dehydrogenase	342
650738217	352	23.4	15	325	8	274	7.0e-28	118	COG1082	Sugar phosphate isomerase/epimerase	274
650738218	270	33.6	3	251	2	247	1.0e-35	143	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650738219	298	27.76	5	291	1	273	1.0e-28	120	COG1082	Sugar phosphate isomerase/epimerase	274
650738220	623	49.28	2	622	1	617	0.0e+00	713	COG3962	TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism	617
650738221	335	29.94	1	333	3	342	2.0e-50	193	COG0673	Predicted dehydrogenase	342
650738222	478	43.16	7	472	1	463	2.0e-123	436	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650738223	272	35.16	1	252	4	254	3.0e-50	191	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
650738224	323	36.83	1	313	3	314	9.0e-64	237	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
650738226	291	29.45	12	282	3	267	4.0e-39	155	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
650738228	303	29.39	7	294	3	274	4.0e-30	125	COG1082	Sugar phosphate isomerase/epimerase	274
650738229	270	38.74	5	253	3	247	1.0e-38	153	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650738232	357	22.75	17	345	1	314	6.0e-24	105	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650738233	302	31	1	292	1	274	4.0e-40	158	COG1082	Sugar phosphate isomerase/epimerase	274
650738234	336	25.6	1	316	2	331	4.0e-43	168	COG0673	Predicted dehydrogenase	342
650738235	262	58.43	1	261	5	271	8.0e-91	326	COG4130	Predicted sugar epimerase, xylose isomerase-like family	272
650738236	322	28.61	1	320	2	322	4.0e-29	122	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650738237	355	31.5	28	352	2	314	6.0e-41	161	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650738239	636	53.38	331	635	1	310	1.0e-104	374	COG3892	Myo-inositol catabolism protein IolC	310
650738240	612	61.2	1	610	1	616	0.0e+00	845	COG3962	TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism	617
650738241	264	58.46	1	259	1	260	3.0e-103	368	COG3718	5-deoxy-D-glucuronate isomerase	270
650738244	535	37.74	97	254	3	157	1.0e-19	91.7	COG3436	Transposase	157
650738245	338	30.37	4	325	1	303	1.0e-33	137	COG3547	Transposase	303
650738249	251	34.43	1	241	5	248	7.0e-43	167	COG1484	DNA replication protein DnaC	254
650738251	411	27.3	7	325	1	303	4.0e-17	82.6	COG3547	Transposase	303
650738252	354	31.18	39	314	9	278	9.0e-31	127	COG4584	Transposase	278
650738254	311	25.99	7	306	1	274	9.0e-30	124	COG1082	Sugar phosphate isomerase/epimerase	274
650738256	342	30.51	1	342	3	341	2.0e-45	176	COG0673	Predicted dehydrogenase	342
650738257	313	27.36	1	313	3	274	4.0e-27	115	COG1082	Sugar phosphate isomerase/epimerase	274
650738258	390	25.17	9	309	1	284	2.0e-39	156	COG0673	Predicted dehydrogenase	342
650738259	337	26.1	1	324	2	341	3.0e-39	156	COG0673	Predicted dehydrogenase	342
650738260	301	32.67	1	292	1	274	4.0e-42	165	COG1082	Sugar phosphate isomerase/epimerase	274
650738262	414	30.63	9	375	1	377	7.0e-47	181	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
650738263	104	39.42	1	103	2	105	2.0e-25	106	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
650738264	372	29.55	12	344	1	330	2.0e-54	206	COG3239	Fatty acid desaturase	343
650738266	337	24.55	11	336	1	311	4.0e-28	119	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650738271	121	27.78	32	121	14	103	2.0e-06	44.9	COG3838	Type IV secretory pathway, VirB2 components (pilins)	108
650738272	110	39.18	7	102	8	102	7.0e-14	69.1	COG3702	Type IV secretory pathway, VirB3 components	105
650738273	790	32.66	2	788	14	794	0.0e+00	543	COG3451	Type IV secretory pathway, VirB4 component	796
650738275	295	18.06	1	287	36	334	2.0e-11	63.1	COG3704	Type IV secretory pathway, VirB6 components	406
650738276	233	30.32	13	231	14	232	2.0e-32	132	COG3736	Type IV secretory pathway, component VirB8	239
650738277	296	28.06	17	294	19	265	4.0e-31	128	COG3504	Type IV secretory pathway, VirB9 components	265
650738278	378	31.62	17	375	3	359	1.0e-49	190	COG2948	Type IV secretory pathway, VirB10 components	360
650738280	577	17.04	67	479	10	432	5.0e-26	112	COG5421	Transposase	480
650738281	346	31.21	4	329	1	303	4.0e-28	118	COG3547	Transposase	303
650738282	355	29.22	17	320	8	289	2.0e-58	219	COG0630	Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase	312
650738283	606	23.27	116	600	98	563	2.0e-65	244	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
650738284	160	35.37	1	147	1	146	2.0e-23	102	COG1522	DNA-binding transcriptional regulator, Lrp family	154
650738285	350	31.19	21	347	12	312	2.0e-38	153	COG1171	Threonine dehydratase	347
650738286	389	47.77	10	385	13	392	9.0e-113	400	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
650738287	437	27.53	34	407	30	407	4.0e-41	162	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
650738288	418	26.87	2	352	1	350	7.0e-47	181	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
650738290	236	46.4	1	219	1	220	5.0e-53	200	COG2135	Putative SOS response-associated peptidase YedK	226
650738295	731	35.96	33	720	11	685	7.0e-114	405	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
650738302	191	32.09	3	187	8	192	3.0e-22	98.4	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
650738304	349	32.48	28	334	16	303	2.0e-29	123	COG3547	Transposase	303
650738306	408	41.04	6	394	4	405	8.0e-78	284	COG2223	Nitrate/nitrite transporter NarK	417
650738307	814	56.73	6	807	1	789	0.0e+00	1051	COG1251	NAD(P)H-nitrite reductase, large subunit	793
650738308	116	34.29	7	110	2	106	4.0e-20	90	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
650738309	861	31.16	3	670	43	764	1.0e-119	424	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
650738310	261	50.21	12	254	5	244	6.0e-63	233	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
650738311	194	26.6	1	185	3	179	1.0e-10	60.3	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
650738312	95	41.98	1	81	3	83	6.0e-18	82.3	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
650738313	94	34.04	3	94	2	94	7.0e-17	78.8	COG3549	Plasmid maintenance system killer protein	94
650738315	189	40.82	3	187	2	197	1.0e-27	116	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650738318	918	34.48	334	911	233	866	3.0e-88	320	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
650738321	117	35.85	12	115	5	109	9.0e-13	65.7	COG4679	Phage-related protein	116
650738326	435	37.53	6	424	1	405	4.0e-80	292	COG0004	Ammonia channel protein AmtB	409
650738329	92	32.98	1	92	2	93	5.0e-09	52.7	COG3668	Plasmid stabilization system protein ParE	98
650738330	311	28.51	60	305	1	225	4.0e-11	62.5	COG3039	Transposase and inactivated derivatives, IS5 family	230
650738336	126	41.27	1	122	2	127	3.0e-23	100	COG3654	Prophage maintenance system killer protein	132
650738338	462	28.8	159	458	28	327	4.0e-32	132	COG0642	Signal transduction histidine kinase	336
650738339	456	49.34	1	437	4	457	2.0e-123	435	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
650738347	269	43.55	9	254	7	254	4.0e-58	218	COG1484	DNA replication protein DnaC	254
650738352	403	32.23	106	392	6	292	2.0e-32	133	COG4974	Site-specific recombinase XerD	300
650738353	313	28.18	10	289	15	281	1.0e-19	90.7	COG4974	Site-specific recombinase XerD	300
650738354	330	35.12	8	294	7	283	3.0e-41	162	COG4974	Site-specific recombinase XerD	300
650738355	93	50	1	91	1	90	2.0e-22	96.9	COG3041	mRNA-degrading endonuclease (mRNA interferase) YafQ, toxin component of the YafQ-DinJ toxin-antitoxin module	91
650738356	87	48.86	1	85	1	88	2.0e-15	73.8	COG3077	Antitoxin component of the RelBE or YafQ-DinJ toxin-antitoxin module	88
650738357	295	33.8	1	280	1	278	4.0e-22	98.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
650738359	253	35.08	8	247	9	254	4.0e-27	115	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650738360	401	32.28	117	391	1	282	6.0e-21	95.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650738368	490	45.68	5	477	1	468	0.0e+00	476	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650738369	273	22.71	14	262	69	330	5.0e-21	94.9	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
650738370	344	28.22	45	328	32	303	2.0e-25	109	COG3547	Transposase	303
650738372	311	39.22	3	151	1	152	8.0e-29	121	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
650738373	274	30	14	264	13	280	4.0e-17	82.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650738375	236	35.43	2	223	1	222	2.0e-31	129	COG1802	DNA-binding transcriptional regulator, GntR family	230
650738377	227	47.32	1	224	1	215	8.0e-57	213	COG3316	Transposase (or an inactivated derivative)	215
650738382	160	18.71	1	133	10	148	5.0e-06	43.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
650738384	96	36.96	1	90	2	91	1.0e-09	54.7	COG3668	Plasmid stabilization system protein ParE	98
650738388	330	35.12	8	294	7	283	3.0e-41	162	COG4974	Site-specific recombinase XerD	300
650738389	313	28.18	10	289	15	281	1.0e-19	90.7	COG4974	Site-specific recombinase XerD	300
650738390	403	32.23	106	392	6	292	2.0e-32	133	COG4974	Site-specific recombinase XerD	300
650738394	988	40.73	619	946	1	323	2.0e-74	274	COG4644	Transposase and inactivated derivatives, TnpA family	323
650738395	193	35.29	4	193	2	205	2.0e-27	115	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650738396	136	43.18	2	132	1	129	1.0e-28	118	COG3742	Uncharacterized protein, contains PIN domain	131
650738397	106	38.27	27	105	1	81	2.0e-09	54.2	COG4423	Uncharacterized protein	81
650738399	99	32.98	1	94	2	95	2.0e-13	67.6	COG4453	Uncharacterized conserved protein, DUF1778 family	95
650738400	88	29.49	9	86	2	74	2.0e-07	47.6	COG3831	WGR domain, predicted DNA-binding domain in MolR	85
650738410	346	31	5	329	2	303	1.0e-27	117	COG3547	Transposase	303
650738413	457	27.46	37	455	4	415	1.0e-36	147	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
650738414	91	37.78	1	90	1	89	8.0e-15	71.8	COG1937	DNA-binding transcriptional regulator, FrmR family	89
650738415	208	41.79	1	185	1	199	2.0e-26	112	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650738417	298	24.75	3	293	1	281	3.0e-18	85.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650738418	329	53.25	9	316	4	263	4.0e-99	354	COG4608	ABC-type oligopeptide transport system, ATPase component	309
650738419	329	57.68	7	320	1	315	2.0e-118	418	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
650738420	330	37.93	12	328	5	314	2.0e-66	246	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
650738421	347	39.13	23	343	6	287	3.0e-50	192	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
650738422	558	24.11	1	558	2	553	9.0e-57	215	COG0747	ABC-type transport system, periplasmic component	556
650738423	90	28.89	1	90	1	88	3.0e-11	60.3	COG2026	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system	90
650738424	74	37.5	3	74	9	80	4.0e-12	63.1	COG4710	Predicted DNA-binding protein with an HTH domain	80
650738426	138	34.11	7	134	5	132	1.0e-15	76	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
650738427	86	37.18	5	81	3	74	6.0e-06	42.6	COG4456	Virulence-associated protein VagC (function unknown)	74
650738432	132	30.15	1	118	4	138	3.0e-17	80.8	COG5573	Predicted nucleic acid-binding protein, contains PIN domain	142
650738434	577	17.04	67	479	10	432	3.0e-25	110	COG5421	Transposase	480
650738436	125	33.33	1	121	1	122	2.0e-06	44.6	COG3415	Transposase	138
650738437	627	29.03	13	613	85	695	0.0e+00	562	COG1328	Anaerobic ribonucleoside-triphosphate reductase	700
650738438	235	31.79	9	196	21	213	3.0e-29	121	COG1180	Pyruvate-formate lyase-activating enzyme	260
650738442	141	42.11	10	139	5	132	3.0e-25	107	COG3474	Cytochrome c2	135
650738445	276	40.83	53	168	1	117	4.0e-11	62.3	COG5433	Predicted transposase YbfD/YdcC associated with H repeats	121
650738448	331	36.61	5	331	7	312	4.0e-67	248	COG0826	Collagenase-like protease, PrtC family	347
650738449	299	27.39	4	293	2	302	3.0e-40	158	COG0826	Collagenase-like protease, PrtC family	347
650738450	386	30.61	280	374	29	126	2.0e-10	60.3	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
650738451	309	68.81	15	309	10	296	4.0e-120	424	COG0214	Pyridoxal biosynthesis lyase PdxS	296
650738452	195	46.91	3	191	1	194	4.0e-54	204	COG0311	Glutamine amidotransferase PdxT (pyridoxal biosynthesis)	194
650738454	195	25	31	124	18	113	6.0e-03	34.2	COG3335	Transposase	132
650738462	137	23.64	25	131	5	114	4.0e-06	44.1	COG2963	Transposase and inactivated derivatives	116
650738464	313	42.35	14	191	2	196	3.0e-25	109	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650738465	383	27.73	172	381	2	257	4.0e-26	112	COG1192	Cellulose biosynthesis protein BcsQ	259
650738469	199	26.61	3	194	5	249	6.0e-20	91	COG1192	Cellulose biosynthesis protein BcsQ	259
650738476	467	24.91	181	450	12	254	3.0e-21	96.6	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
650738482	185	34.36	1	178	2	196	5.0e-22	97.5	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650738483	324	20.34	23	308	15	273	7.0e-18	85	COG0863	DNA modification methylase	302
650738487	209	31.08	1	207	3	253	2.0e-34	138	COG1192	Cellulose biosynthesis protein BcsQ	259
650738490	193	35.29	4	193	2	205	2.0e-27	115	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650738491	988	40.73	619	946	1	323	2.0e-74	274	COG4644	Transposase and inactivated derivatives, TnpA family	323
650738495	92	35.56	1	88	2	91	3.0e-10	56.6	COG3668	Plasmid stabilization system protein ParE	98
650741952	490	45.41	40	486	1	408	2.0e-120	426	COG0593	Chromosomal replication initiation ATPase DnaA	408
650741953	283	39.29	6	283	6	312	8.0e-68	250	COG0627	S-formylglutathione hydrolase FrmB	316
650741954	67	65.67	1	67	1	67	2.0e-22	97.1	COG1278	Cold shock protein, CspA family	67
650741955	144	37.9	23	144	1	115	4.0e-14	70.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
650741956	378	42.89	1	376	1	390	1.0e-72	266	COG0183	Acetyl-CoA acetyltransferase	392
650741957	786	34.34	3	298	2	287	1.0e-62	234	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
650741958	596	34.48	34	461	5	393	8.0e-69	255	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650741959	188	42.86	4	185	1	173	7.0e-36	143	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
650741960	237	29.18	2	224	24	256	5.0e-24	104	COG0555	ABC-type sulfate transport system, permease component	274
650741961	304	25.08	5	299	6	257	5.0e-18	85.4	COG0725	ABC-type molybdate transport system, periplasmic component	258
650741962	125	37.93	9	124	2	113	5.0e-17	80	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
650741963	173	33.12	20	173	5	158	6.0e-27	113	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
650741965	183	47.62	2	182	18	206	3.0e-36	145	COG1584	Succinate-acetate transporter protein	207
650741966	75	24.32	1	74	1	74	4.0e-11	59.6	COG1826	Sec-independent protein translocase protein TatA	94
650741967	85	21.69	1	83	1	81	5.0e-09	52.7	COG1826	Sec-independent protein translocase protein TatA	94
650741968	213	31.84	13	212	2	194	8.0e-33	133	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
650741969	180	46.63	1	177	1	172	4.0e-48	184	COG1791	Acireductone dioxygenase (methionine salvage), cupin superfamily	181
650741970	232	43.48	3	205	2	208	6.0e-55	207	COG4229	Enolase-phosphatase E1 involved in merthionine salvage	229
650741971	509	29.98	22	506	21	514	3.0e-59	222	COG0815	Apolipoprotein N-acyltransferase	518
650741972	161	18.03	24	144	1	119	3.0e-08	51.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
650741973	220	56.6	5	216	3	213	2.0e-79	288	COG0036	Pentose-5-phosphate-3-epimerase	220
650741974	525	36.86	18	525	39	565	2.0e-87	316	COG5360	Uncharacterized conserved protein, heparinase superfamily	566
650741975	332	41.82	3	331	2	323	2.0e-120	425	COG1087	UDP-glucose 4-epimerase	329
650741976	374	28.65	18	371	22	379	5.0e-30	125	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650741977	155	41.03	1	154	4	154	5.0e-30	123	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
650741978	513	63.3	7	513	2	515	0.0e+00	735	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
650741979	185	19.43	10	178	3	177	1.0e-04	39.8	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
650741980	653	46.28	11	653	3	635	0.0e+00	773	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
650741981	212	44.84	1	210	1	222	2.0e-54	205	COG0283	Cytidylate kinase	222
650741982	445	43.12	14	441	9	428	3.0e-105	375	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
650741985	409	53	11	409	3	396	2.0e-125	442	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650741986	279	21.25	20	279	13	282	2.0e-08	52.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650741987	283	29.86	6	276	12	286	1.0e-28	120	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
650741988	745	40.08	12	709	4	705	0.0e+00	556	COG0557	Exoribonuclease R	706
650741989	530	32.44	154	442	69	364	9.0e-51	195	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
650741990	55	48.94	7	53	4	50	2.0e-08	51	COG0267	Ribosomal protein L33	50
650741991	379	41.88	1	379	1	379	7.0e-102	364	COG0763	Lipid A disaccharide synthetase	381
650741992	291	28.98	1	280	1	266	2.0e-30	126	COG0388	Predicted amidohydrolase	274
650741994	575	30.17	333	446	35	143	6.0e-09	56.1	COG2010	Cytochrome c, mono- and diheme variants	150
650741997	263	28.76	30	258	14	241	2.0e-29	122	COG3403	Uncharacterized protein YcgG, contains conserved FPC and CPF motifs	257
650741998	215	25	8	195	6	201	3.0e-16	78.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
650742001	499	25.71	14	292	7	278	1.0e-26	114	COG4584	Transposase	278
650742002	275	41.91	16	253	14	254	4.0e-51	195	COG1484	DNA replication protein DnaC	254
650742004	346	31.21	4	329	1	303	4.0e-28	118	COG3547	Transposase	303
650742006	447	24.92	19	334	8	303	2.0e-08	54.1	COG2814	Predicted arabinose efflux permease, MFS family	394
650742011	346	31.21	4	329	1	303	4.0e-28	118	COG3547	Transposase	303
650742012	577	17.76	67	479	10	432	4.0e-25	110	COG5421	Transposase	480
650742014	478	17.66	67	476	10	429	3.0e-24	106	COG5421	Transposase	480
650742015	111	33.33	1	110	1	105	3.0e-08	50.3	COG3415	Transposase	138
650742016	499	25.71	14	292	7	278	1.0e-26	114	COG4584	Transposase	278
650742017	275	41.91	16	253	14	254	4.0e-51	195	COG1484	DNA replication protein DnaC	254
650742021	408	45.2	7	399	3	388	4.0e-108	384	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
650742022	326	34.35	41	296	4	257	1.0e-51	197	COG1351	Thymidylate synthase ThyX	273
650742024	209	27.84	1	209	1	255	2.0e-19	89.1	COG1192	Cellulose biosynthesis protein BcsQ	259
650742025	456	38.41	185	451	1	284	3.0e-44	173	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
650742026	366	45.36	4	366	3	376	2.0e-91	329	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
650742027	124	51.2	1	123	6	130	1.0e-38	151	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
650742028	960	61.39	468	928	29	496	0.0e+00	679	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
650742029	191	26.44	8	178	6	171	8.0e-20	90.4	COG3040	Bacterial lipocalin	174
650742030	580	34.46	265	560	25	309	3.0e-43	170	COG0616	Periplasmic serine protease, ClpP class	317
650742031	152	37.76	4	146	2	141	9.0e-26	109	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
650742032	313	47.48	1	313	1	314	1.0e-101	362	COG0275	16S rRNA C1402 N4-methylase RsmH	314
650742033	289	35.19	1	106	1	104	8.0e-12	64.7	COG5462	Predicted secreted (periplasmic) protein	138
650742034	696	30.38	59	589	16	597	3.0e-95	343	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
650742035	481	42.46	22	481	11	473	2.0e-100	360	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
650742036	451	43.96	4	450	2	451	6.0e-100	358	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
650742037	362	44.13	20	362	1	316	4.0e-57	215	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
650742038	461	41.76	12	455	5	446	3.0e-99	355	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
650742039	387	36.24	14	367	8	372	4.0e-58	218	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
650742040	368	34.99	8	365	2	357	2.0e-67	249	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
650742041	479	50.43	4	466	3	459	0.0e+00	561	COG0773	UDP-N-acetylmuramate-alanine ligase	459
650742042	309	49.3	20	302	2	287	1.0e-85	309	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
650742043	301	40.13	2	297	3	316	8.0e-76	277	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
650742044	292	28.36	15	283	4	268	1.0e-21	97	COG1589	Cell division septal protein FtsQ	269
650742045	435	41.13	34	404	10	379	3.0e-98	352	COG0849	Cell division ATPase FtsA	418
650742046	522	50.75	11	343	6	337	3.0e-105	375	COG0206	Cell division GTPase FtsZ	338
650742048	697	23.55	28	485	1	440	3.0e-26	113	COG0658	Predicted membrane metal-binding protein	453
650742049	341	21.78	22	309	7	305	8.0e-19	88.3	COG1216	Glycosyltransferase, GT2 family	305
650742050	494	43	289	493	30	225	1.0e-54	207	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
650742051	146	34.13	25	145	12	135	3.0e-08	51.1	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
650742052	165	56.95	1	151	1	150	2.0e-55	208	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
650742053	801	38.62	14	793	6	731	0.0e+00	590	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
650742054	264	37.01	1	264	1	280	4.0e-55	208	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
650742056	307	20.92	1	305	4	266	9.0e-15	74.4	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
650742057	246	37.33	9	232	10	233	1.0e-45	176	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
650742059	373	30.23	13	349	12	346	8.0e-51	194	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
650742060	276	36.99	36	276	13	255	1.0e-48	186	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
650742063	203	32.54	3	203	4	195	5.0e-26	111	COG1335	Nicotinamidase-related amidase	205
650742064	250	37.26	5	249	1	251	2.0e-34	139	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650742065	593	42.61	7	573	10	570	0.0e+00	619	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
650742067	137	34.78	7	120	2	115	6.0e-20	89.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
650742068	1020	38.58	3	1007	1	1006	0.0e+00	814	COG0841	Multidrug efflux pump subunit AcrB	1009
650742069	394	27.93	23	377	1	367	3.0e-32	132	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
650742070	507	30.9	21	499	1	456	3.0e-54	206	COG1538	Outer membrane protein TolC	457
650742071	242	26	23	222	3	201	5.0e-08	51.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650742072	289	33.8	14	287	2	288	9.0e-38	150	COG3327	DNA-binding transcriptional regulator PaaX (phenylacetic acid degradation)	291
650742073	293	26.39	17	156	1	124	3.0e-09	55.9	COG3293	Transposase	124
650742079	346	31.21	4	329	1	303	4.0e-28	118	COG3547	Transposase	303
650742080	115	22.88	1	114	1	116	5.0e-08	49.7	COG3293	Transposase	124
650742081	128	26.98	3	128	1	123	2.0e-07	48.2	COG3293	Transposase	124
650742082	401	43.65	13	395	8	389	1.0e-99	356	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
650742083	733	28.85	185	726	66	618	2.0e-73	271	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
650742086	132	28.46	2	128	3	128	4.0e-12	63.8	COG5443	Flagellar biosynthesis regulator FlbT	148
650742087	294	20.07	7	285	2	279	6.0e-12	65.1	COG1344	Flagellin and related hook-associated protein FlgL	360
650742088	353	20.57	54	353	43	357	2.0e-06	46.6	COG1344	Flagellin and related hook-associated protein FlgL	360
650742089	485	22.56	1	485	1	552	7.0e-34	138	COG1256	Flagellar hook-associated protein FlgK	552
650742090	425	31.9	3	425	1	423	1.0e-45	177	COG1749	Flagellar hook protein FlgE	423
650742092	253	33.8	34	244	2	213	4.0e-20	92	COG1843	Flagellar hook assembly protein FlgD	222
650742095	415	37.26	95	402	1	313	3.0e-49	189	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
650742096	410	22.86	2	410	1	459	8.0e-19	88.5	COG3349	Uncharacterized conserved protein, contains NAD-binding domain and a Fe-S cluster	485
650742097	290	36.94	19	281	15	281	6.0e-36	144	COG1562	Phytoene/squalene synthetase	288
650742098	278	23.94	15	268	19	271	2.0e-22	100	COG1562	Phytoene/squalene synthetase	288
650742099	375	23.56	3	348	22	355	2.0e-15	77.3	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
650742100	361	24.93	25	347	3	312	1.0e-31	130	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650742101	349	20.92	16	320	8	294	4.0e-03	36.2	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
650742102	84	50	1	81	1	82	1.0e-06	45	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
650742103	393	27.37	7	379	9	362	1.0e-15	77.9	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
650742106	259	31.54	33	259	3	242	6.0e-24	104	COG1587	Uroporphyrinogen-III synthase	248
650742107	335	46.47	22	333	3	302	3.0e-85	308	COG0181	Porphobilinogen deaminase	307
650742108	363	51.17	16	356	2	337	6.0e-108	384	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
650742109	838	46.16	32	833	5	748	0.0e+00	780	COG0058	Glucan phosphorylase	750
650742110	423	50	10	417	1	386	0.0e+00	508	COG0448	ADP-glucose pyrophosphorylase	393
650742111	479	47.84	1	479	1	481	0.0e+00	488	COG0297	Glycogen synthase	487
650742112	1030	36.6	2	1016	1	1009	0.0e+00	838	COG0841	Multidrug efflux pump subunit AcrB	1009
650742113	1065	36.03	2	1049	1	1009	0.0e+00	844	COG0841	Multidrug efflux pump subunit AcrB	1009
650742114	386	33.42	1	376	4	365	1.0e-30	127	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
650742115	502	37.25	50	499	4	451	2.0e-54	207	COG1538	Outer membrane protein TolC	457
650742116	184	32.04	2	174	6	181	3.0e-20	91.8	COG0406	Broad specificity phosphatase PhoE	208
650742117	221	29.65	12	220	54	279	3.0e-26	112	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
650742118	400	30.79	36	389	9	369	4.0e-55	208	COG2821	Membrane-bound lytic murein transglycosylase	373
650742120	630	53.74	2	630	1	627	0.0e+00	743	COG3158	K+ transporter	627
650742123	852	30.27	13	598	3	598	2.0e-54	207	COG1042	Acyl-CoA synthetase (NDP forming)	598
650742124	299	22.73	13	297	2	282	6.0e-06	45.3	COG5006	Threonine/homoserine efflux transporter RhtA	292
650742125	291	53.52	1	283	1	284	2.0e-95	342	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
650742126	311	54.11	2	311	1	311	5.0e-82	297	COG2025	Electron transfer flavoprotein, alpha subunit	313
650742127	249	52.31	1	249	1	260	9.0e-72	263	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
650742129	969	37.12	1	901	2	920	0.0e+00	620	COG1391	Glutamine synthetase adenylyltransferase	963
650742130	157	51.95	1	154	2	155	1.0e-53	202	COG1225	Peroxiredoxin	157
650742131	191	22.15	38	188	13	168	5.0e-12	64.3	COG1495	Disulfide bond formation protein DsbB	170
650742132	182	40	13	182	37	204	1.0e-41	162	COG2941	Demethoxyubiquinone hydroxylase, CLK1/Coq7/Cat5 family	204
650742134	157	22.46	18	148	18	155	1.0e-07	49.3	COG5490	Uncharacterized protein	158
650742135	728	65.66	22	685	1	662	0.0e+00	1076	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
650742138	158	40.59	38	138	14	114	3.0e-15	74.9	COG5349	Uncharacterized conserved protein, DUF983 family	126
650742139	162	45.57	4	161	3	159	2.0e-36	145	COG5328	Uncharacterized protein, UPF0262 family	160
650742140	367	47.73	8	351	3	336	7.0e-110	390	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
650742141	270	21.84	11	264	17	300	8.0e-18	84.4	COG4322	Uncharacterized protein	304
650742142	444	52.87	16	444	1	435	0.0e+00	557	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
650742143	324	38.46	7	301	5	288	2.0e-65	242	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
650742144	647	25.73	38	647	15	594	6.0e-62	232	COG0729	Outer membrane translocation and assembly module TamA	594
650742145	1319	23.03	1	1319	4	1278	5.0e-72	267	COG2911	Autotransporter translocation and assembly factor TamB	1278
650742146	425	67.06	1	425	1	422	0.0e+00	627	COG0148	Enolase	423
650742147	153	35.92	6	147	1	123	1.0e-15	75.7	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
650742149	162	55.24	59	161	16	118	1.0e-25	109	COG3761	NADH:ubiquinone oxidoreductase 17.2 kD subunit	118
650742151	193	21.05	61	190	22	152	8.0e-07	47.3	COG4765	Uncharacterized protein	164
650742152	364	30.3	200	364	26	188	2.0e-22	100	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
650742153	361	30.59	201	361	19	188	7.0e-22	98.4	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
650742154	255	25.49	4	250	3	248	2.0e-21	96.3	COG2365	Protein tyrosine/serine phosphatase	249
650742157	474	47.69	6	474	2	477	0.0e+00	545	COG0469	Pyruvate kinase	477
650742158	104	69.79	9	104	9	104	2.0e-33	133	COG3492	Uncharacterized protein	104
650742159	91	58.11	18	91	11	84	1.0e-16	78	COG3750	Uncharacterized conserved protein, UPF0335 family	85
650742160	331	55.62	4	331	3	330	0.0e+00	478	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
650742161	357	48.74	1	355	1	348	2.0e-115	409	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
650742162	431	27.15	47	429	1	370	1.0e-23	104	COG3174	Uncharacterized membrane protein, DUF4010 family	371
650742163	295	27.15	44	261	33	251	4.0e-12	65.8	COG5607	CHAD domain (function unknown)	283
650742164	761	30.39	22	583	106	652	3.0e-101	363	COG0209	Ribonucleotide reductase alpha subunit	696
650742165	335	40.96	3	328	1	332	4.0e-81	294	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650742166	837	47.7	276	831	3	565	0.0e+00	579	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
650742167	317	44.19	4	311	2	308	5.0e-77	281	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
650742168	564	61	226	563	1	339	2.0e-96	347	COG1299	Phosphotransferase system, fructose-specific IIC component	343
650742169	146	31.62	12	146	6	139	1.0e-18	85.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
650742170	305	33.11	1	302	1	303	1.0e-58	220	COG1893	Ketopantoate reductase	307
650742171	211	32.81	10	190	7	197	2.0e-15	75.8	COG3222	Uncharacterized conserved protein, glycosyltransferase A (GT-A) superfamily, DUF2064 family	211
650742172	705	39.78	247	680	3	454	2.0e-103	370	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
650742174	435	23.94	17	414	31	387	5.0e-11	62.9	COG2814	Predicted arabinose efflux permease, MFS family	394
650742175	307	33.11	10	304	3	299	1.0e-44	173	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
650742176	522	26.96	16	499	6	472	6.0e-46	179	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650742177	237	34.25	6	224	7	210	8.0e-44	170	COG0684	Regulator of RNase E activity RraA	210
650742178	287	38.01	1	281	23	298	1.0e-37	150	COG0501	Zn-dependent protease with chaperone function	302
650742179	176	38.51	27	174	1	146	8.0e-25	106	COG0071	Molecular chaperone IbpA, HSP20 family	146
650742183	474	34.91	71	470	12	399	1.0e-74	274	COG4671	Predicted glycosyl transferase	400
650742184	454	31.53	142	422	86	374	1.0e-33	137	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650742185	399	26.99	1	387	1	368	9.0e-25	108	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650742186	602	38.28	8	587	6	563	2.0e-120	426	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650742188	218	41.85	23	202	5	187	7.0e-32	130	COG0406	Broad specificity phosphatase PhoE	208
650742189	453	53.94	1	419	1	413	0.0e+00	528	COG1004	UDP-glucose 6-dehydrogenase	414
650742190	233	36.9	1	227	3	251	5.0e-31	128	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650742191	895	64.12	7	893	1	861	0.0e+00	1252	COG1048	Aconitase A	861
650742192	230	47.18	30	220	2	196	3.0e-51	195	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
650742193	217	47.06	1	217	1	221	9.0e-30	123	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
650742194	589	29.24	156	542	5	383	2.0e-53	204	COG0006	Xaa-Pro aminopeptidase	384
650742196	305	31.67	11	295	6	300	1.0e-51	197	COG2264	Ribosomal protein L11 methylase PrmA	300
650742197	728	46.36	6	635	1	643	0.0e+00	583	COG0210	Superfamily I DNA or RNA helicase	655
650742198	310	40.69	24	308	7	291	1.0e-68	253	COG0685	5,10-methylenetetrahydrofolate reductase	291
650742199	266	37.45	1	242	2	234	2.0e-46	179	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
650742200	208	22.22	13	200	8	200	4.0e-20	91.5	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
650742201	174	35.06	9	161	4	153	2.0e-32	131	COG0779	Ribosome maturation factor RimP	153
650742202	506	56.63	163	357	1	190	2.0e-50	194	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
650742204	887	60.67	384	886	1	504	0.0e+00	644	COG0532	Translation initiation factor IF-2, a GTPase	509
650742205	140	36.97	17	133	3	118	2.0e-22	98.3	COG0858	Ribosome-binding factor A	118
650742206	322	47.12	1	208	5	211	1.0e-57	217	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
650742207	1089	24.94	19	408	16	381	2.0e-31	131	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650742209	344	28.22	45	328	32	303	2.0e-25	109	COG3547	Transposase	303
650742212	104	53.4	1	103	1	103	7.0e-31	125	COG0261	Ribosomal protein L21	103
650742213	89	66.67	1	87	1	87	5.0e-30	122	COG0211	Ribosomal protein L27	87
650742214	332	57.44	1	331	1	336	4.0e-130	457	COG0536	GTPase involved in cell partioning and DNA repair	369
650742215	383	54.08	10	374	5	369	6.0e-117	414	COG0263	Glutamate 5-kinase	369
650742216	368	23.05	65	368	1	303	8.0e-15	74.9	COG0668	Small-conductance mechanosensitive channel	316
650742217	185	23.58	14	131	6	118	9.0e-04	36.9	COG3794	Plastocyanin	128
650742218	262	44.44	1	247	3	253	1.0e-68	252	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
650742219	164	27.34	20	155	18	150	2.0e-04	38.9	COG1714	Uncharacterized membrane protein YckC, RDD family	172
650742220	310	58.2	1	310	5	314	5.0e-115	407	COG0462	Phosphoribosylpyrophosphate synthetase	314
650742221	206	34.76	1	204	1	206	7.0e-25	107	COG0625	Glutathione S-transferase	211
650742222	194	40	8	154	5	164	9.0e-29	120	COG0406	Broad specificity phosphatase PhoE	208
650742223	387	44.27	5	387	4	377	6.0e-99	354	COG1454	Alcohol dehydrogenase, class IV	377
650742224	389	31.83	22	386	67	463	2.0e-58	220	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
650742226	284	27.72	41	237	41	216	3.0e-18	85.7	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
650742228	695	58.93	4	693	5	690	0.0e+00	917	COG0480	Translation elongation factor EF-G, a GTPase	697
650742229	96	44.21	5	96	4	97	2.0e-09	53.8	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
650742230	422	42.66	56	419	16	382	1.0e-83	303	COG1686	D-alanyl-D-alanine carboxypeptidase	389
650742232	221	47.98	1	220	7	229	3.0e-55	208	COG0571	dsRNA-specific ribonuclease	235
650742233	295	45.76	1	294	2	296	2.0e-100	358	COG1159	GTPase Era, involved in 16S rRNA processing	298
650742234	372	32.3	1	372	1	384	2.0e-44	173	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650742235	403	33.17	1	402	1	388	5.0e-63	235	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650742236	567	40.26	26	555	12	528	4.0e-108	385	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650742237	698	38.34	293	594	2	306	7.0e-75	275	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
650742238	332	20.7	36	315	1	280	2.0e-15	76.7	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
650742240	626	22.32	25	257	13	241	1.0e-10	61.9	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
650742241	318	29.78	72	248	1	176	6.0e-23	101	COG1633	Rubrerythrin	176
650742242	318	31.68	10	316	12	332	2.0e-61	229	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
650742243	221	26.64	1	211	1	201	5.0e-23	101	COG0625	Glutathione S-transferase	211
650742244	275	34.02	1	270	10	298	4.0e-41	161	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
650742245	298	26.51	1	293	2	331	2.0e-38	152	COG0859	ADP-heptose:LPS heptosyltransferase	334
650742246	341	27.49	58	341	92	379	4.0e-27	115	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650742247	581	30.56	1	563	1	541	8.0e-81	295	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
650742248	442	38.39	5	433	1	429	2.0e-100	360	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
650742250	196	34.41	29	121	2	88	5.0e-11	61.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
650742251	104	41.76	3	93	1	91	1.0e-24	104	COG0776	Bacterial nucleoid DNA-binding protein	94
650742252	320	56.79	1	320	1	322	2.0e-110	391	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
650742253	357	46.87	1	332	1	334	2.0e-95	342	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
650742254	67	59.65	1	57	1	57	1.0e-14	71.4	COG0333	Ribosomal protein L32	57
650742256	165	27.97	5	143	5	146	6.0e-15	73.9	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
650742257	529	27.73	2	527	21	607	6.0e-50	192	COG3211	Secreted phosphatase, PhoX family	616
650742258	492	49.04	19	485	2	465	0.0e+00	507	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650742260	407	17.35	86	394	1	305	6.0e-06	45.7	COG0582	Integrase	309
650742265	100	43.96	10	100	3	93	2.0e-15	74.2	COG4453	Uncharacterized conserved protein, DUF1778 family	95
650742271	133	37.04	1	106	1	107	3.0e-10	57.6	COG3415	Transposase	138
650742272	407	48.67	25	398	9	375	8.0e-96	344	COG3328	Transposase (or an inactivated derivative)	379
650742273	157	33.33	25	154	1	132	1.0e-14	72.8	COG3335	Transposase	132
650742277	445	20.72	23	397	3	378	6.0e-16	78.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650742278	345	22.81	1	344	1	371	1.0e-17	84.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650742279	349	22.46	1	340	1	370	4.0e-17	82.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650742280	214	34.85	91	213	20	150	3.0e-16	78.7	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
650742282	423	30.52	25	391	18	358	2.0e-47	183	COG3328	Transposase (or an inactivated derivative)	379
650742283	786	15.82	7	760	24	754	2.0e-12	68	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
650742284	241	29.11	9	220	11	223	2.0e-06	46.3	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
650742285	340	29.19	41	330	1	292	2.0e-21	97.1	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
650742286	524	26.57	7	520	3	540	1.0e-29	124	COG1178	ABC-type Fe3+ transport system, permease component	540
650742287	349	33.8	1	346	2	351	3.0e-60	225	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
650742288	407	25.81	66	323	61	338	9.0e-12	65	COG1566	Multidrug resistance efflux pump	352
650742289	791	19.95	423	788	6	406	4.0e-16	80.7	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
650742290	250	46.67	21	239	2	226	3.0e-72	265	COG1136	ABC-type lipoprotein export system, ATPase component	226
650742291	110	29.17	5	100	3	97	1.0e-08	51.8	COG1993	PII-like signaling protein	109
650742292	175	43.2	51	175	1	125	1.0e-25	109	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
650742293	414	32.23	12	411	4	422	1.0e-46	181	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
650742294	709	52.84	9	236	1	226	2.0e-78	287	COG1136	ABC-type lipoprotein export system, ATPase component	226
650742295	412	29.84	27	397	6	353	3.0e-21	96.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
650742296	1018	29.74	4	1014	1	1008	0.0e+00	562	COG0841	Multidrug efflux pump subunit AcrB	1009
650742297	349	24.29	12	343	17	368	4.0e-07	49.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
650742298	453	24.42	30	442	14	447	5.0e-11	62.5	COG1538	Outer membrane protein TolC	457
650742299	244	47.41	20	244	3	229	2.0e-51	195	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650742300	469	25.79	146	461	21	328	9.0e-29	121	COG0642	Signal transduction histidine kinase	336
650742302	153	30.84	18	124	1	104	2.0e-06	45.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
650742303	609	33.33	15	448	6	443	4.0e-55	209	COG0038	H+/Cl- antiporter ClcA	443
650742304	402	25.65	41	387	24	325	1.0e-45	177	COG1171	Threonine dehydratase	347
650742305	331	25.23	8	329	13	322	9.0e-20	91.4	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650742306	344	35.94	17	334	1	316	1.0e-42	167	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650742308	146	24.24	6	104	15	111	4.0e-09	54.4	COG1917	Cupin domain protein related to quercetin dioxygenase	131
650742309	414	29.59	1	361	3	345	5.0e-35	142	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
650742310	271	21.99	36	245	48	286	1.0e-08	53.8	COG0657	Acetyl esterase/lipase	312
650742311	255	34.18	17	251	3	229	6.0e-48	184	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
650742313	279	37.59	1	276	2	287	6.0e-54	204	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
650742314	75	45.33	1	73	1	74	2.0e-12	63.7	COG0298	Hydrogenase maturation factor	82
650742315	364	43.27	22	360	29	361	6.0e-100	357	COG0409	Hydrogenase maturation factor	364
650742316	754	39.15	4	751	1	746	0.0e+00	669	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
650742317	338	40.99	5	338	1	339	2.0e-72	266	COG0309	Hydrogenase maturation factor	339
650742318	295	42.03	62	264	1	200	4.0e-58	218	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
650742319	113	42.86	1	112	1	112	1.0e-22	98.4	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
650742320	65	44.44	8	61	2	55	1.0e-11	61.4	COG1773	Rubredoxin	55
650742323	191	35.95	6	158	5	157	7.0e-27	113	COG0680	Ni,Fe-hydrogenase maturation factor	160
650742324	244	50.23	26	240	12	227	8.0e-56	210	COG1969	Ni,Fe-hydrogenase I cytochrome b subunit	227
650742325	598	57.53	16	598	1	545	0.0e+00	698	COG0374	Ni,Fe-hydrogenase I large subunit	545
650742326	373	58.74	7	354	3	350	0.0e+00	495	COG1740	Ni,Fe-hydrogenase I small subunit	355
650742327	131	27.52	20	122	14	122	2.0e-05	41.1	COG3631	Ketosteroid isomerase-related protein	133
650742328	148	31.16	5	139	3	140	1.0e-17	82.6	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
650742329	512	29.9	174	464	9	265	8.0e-31	128	COG1575	1,4-dihydroxy-2-naphthoate octaprenyltransferase	303
650742330	216	28.12	66	159	12	107	1.0e-06	46.8	COG0607	Rhodanese-related sulfurtransferase	110
650742331	345	30.19	21	317	13	303	2.0e-21	96.9	COG3301	Formate-dependent nitrite reductase, membrane component NrfD	305
650742332	180	40.76	1	179	8	191	8.0e-39	153	COG0437	Fe-S-cluster-containing dehydrogenase component	203
650742333	731	28.61	1	728	2	763	4.0e-96	346	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
650742334	333	34.04	48	329	8	283	7.0e-49	187	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
650742338	331	42.26	19	312	24	333	7.0e-65	240	COG3376	High-affinity nickel permease	342
650742341	332	36.64	36	321	7	285	3.0e-60	225	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
650742342	486	46.95	12	486	4	465	0.0e+00	485	COG2870	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase	467
650742343	290	34.1	7	267	22	269	2.0e-68	252	COG2326	Polyphosphate kinase 2, PPK2 family	270
650742344	240	59.07	1	235	1	237	4.0e-85	307	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650742345	261	53.36	1	252	1	250	1.0e-88	319	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650742346	308	38.33	11	304	11	308	4.0e-42	165	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
650742347	300	42.33	1	299	3	297	2.0e-47	183	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650742348	381	35.26	22	379	4	366	8.0e-54	204	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650742350	224	44.89	1	222	1	224	8.0e-54	203	COG2135	Putative SOS response-associated peptidase YedK	226
650742354	236	50	11	230	6	227	6.0e-77	280	COG4227	Antirestriction protein ArdC	316
650742355	403	32.23	106	392	6	292	2.0e-32	133	COG4974	Site-specific recombinase XerD	300
650742356	313	28.18	10	289	15	281	1.0e-19	90.7	COG4974	Site-specific recombinase XerD	300
650742357	330	35.12	8	294	7	283	3.0e-41	162	COG4974	Site-specific recombinase XerD	300
650742362	661	24	12	206	4	186	5.0e-07	49.9	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
650742363	141	21.99	3	139	2	140	9.0e-07	46.3	COG1848	Predicted nucleic acid-binding protein, contains PIN domain	140
650742364	80	32.5	1	80	2	80	1.0e-08	51.6	COG4118	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor	84
650742368	311	20.79	13	310	17	280	8.0e-12	64.6	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
650742370	100	61.76	1	100	3	102	2.0e-28	117	COG5489	Uncharacterized conserved protein, DUF736 family	107
650742378	179	41.18	3	172	2	169	2.0e-34	138	COG4959	Type IV secretory pathway, protease TraF	173
650742380	682	38.44	88	403	8	320	1.0e-47	185	COG3843	Type IV secretory pathway, VirD2 components (relaxase)	326
650742383	669	38.27	1	579	4	579	0.0e+00	554	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
650742385	335	42.31	1	304	26	333	4.0e-80	291	COG4962	Pilus assembly protein, ATPase of CpaF family	355
650742386	110	48.91	18	109	19	108	5.0e-13	66.4	COG3838	Type IV secretory pathway, VirB2 components (pilins)	108
650742387	90	42.55	1	90	1	93	1.0e-17	81.6	COG5268	Type IV secretory pathway, TrbD component	93
650742388	873	35.02	1	817	3	796	0.0e+00	595	COG3451	Type IV secretory pathway, VirB4 component	796
650742389	260	37.87	21	255	21	250	9.0e-34	137	COG5314	Conjugal transfer/entry exclusion protein	252
650742391	432	32.87	4	423	29	446	4.0e-42	166	COG3846	Type IV secretory pathway, TrbL components	452
650742392	236	47.81	1	228	1	228	1.0e-62	233	COG3701	Type IV secretory pathway, TrbF components	228
650742393	326	37.2	76	324	14	253	3.0e-47	182	COG3504	Type IV secretory pathway, VirB9 components	265
650742394	419	33.42	15	417	3	356	2.0e-55	210	COG2948	Type IV secretory pathway, VirB10 components	360
650742395	105	41.18	1	68	1	66	1.0e-09	55	COG5639	Uncharacterized protein	77
650742396	104	33.68	6	100	1	95	2.0e-13	67.6	COG4453	Uncharacterized conserved protein, DUF1778 family	95
650742398	680	43.78	1	678	1	681	0.0e+00	607	COG4930	Predicted ATP-dependent Lon-type protease	683
650742407	64	36.07	1	59	9	69	1.0e-04	38.4	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
650742408	423	29.2	191	396	74	290	1.0e-15	77.9	COG4974	Site-specific recombinase XerD	300
650742410	827	35.45	144	826	1	650	0.0e+00	502	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
650742411	357	50.87	1	340	2	335	2.0e-117	415	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
650742413	301	22.56	40	297	5	262	7.0e-13	68.1	COG1729	Periplasmic TolA-binding protein (function unknown)	262
650742414	389	27.35	12	247	23	265	7.0e-26	111	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
650742415	641	59.27	9	605	1	595	0.0e+00	760	COG0465	ATP-dependent Zn proteases	596
650742416	292	35.76	4	288	2	284	6.0e-44	171	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
650742417	253	32.28	1	250	2	254	1.0e-24	107	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650742418	717	63.74	2	695	1	692	0.0e+00	979	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
650742422	124	40.8	1	124	16	136	5.0e-11	60	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
650742424	184	39.87	1	158	1	151	7.0e-42	163	COG0242	Peptide deformylase	168
650742425	218	28.06	6	199	19	214	5.0e-26	111	COG5590	Ubiquinone biosynthesis protein COQ9	229
650742426	396	40.25	4	396	1	387	5.0e-61	228	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
650742427	465	56.86	63	460	1	400	8.0e-123	434	COG0004	Ammonia channel protein AmtB	409
650742428	809	31.83	10	808	78	857	0.0e+00	465	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
650742430	304	33.7	18	291	6	250	3.0e-43	169	COG1830	Fructose-bisphosphate aldolase class Ia, DhnA family	265
650742431	206	41.06	4	206	8	207	2.0e-42	165	COG0352	Thiamine monophosphate synthase	211
650742433	667	16.78	3	281	2	276	1.0e-08	55.1	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
650742438	906	49.49	200	590	74	465	8.0e-112	398	COG1530	Ribonuclease G or E	487
650742441	505	33.89	23	258	1	237	9.0e-39	155	COG4584	Transposase	278
650742442	250	29.96	1	244	5	251	2.0e-40	159	COG1484	DNA replication protein DnaC	254
650742443	408	49.15	21	372	5	350	3.0e-93	335	COG3328	Transposase (or an inactivated derivative)	379
650742444	364	50.89	20	355	49	375	3.0e-91	328	COG3328	Transposase (or an inactivated derivative)	379
650742446	79	53.85	1	78	2	79	2.0e-20	90.6	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
650742447	254	53.6	1	249	1	247	6.0e-88	317	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
650742448	173	34.81	9	166	3	160	2.0e-11	62.2	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
650742449	189	24.83	40	188	9	157	6.0e-12	64.1	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
650742450	77	47.46	19	77	19	77	3.0e-03	33.3	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
650742451	251	41.08	14	251	16	246	3.0e-37	148	COG0356	FoF1-type ATP synthase, membrane subunit a	246
650742453	1165	28.56	4	1156	2	1163	0.0e+00	496	COG1196	Chromosome segregation ATPase	1163
650742454	209	27.55	24	209	64	242	2.0e-17	82.6	COG1651	Protein-disulfide isomerase	244
650742455	171	49.06	1	159	6	164	3.0e-39	154	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
650742457	466	55.97	1	456	1	453	0.0e+00	572	COG1066	Predicted ATP-dependent serine protease	456
650742458	187	27.56	1	156	1	155	6.0e-16	77.2	COG1286	Uncharacterized membrane protein, required for colicin V production	182
650742459	493	52.88	16	479	1	459	0.0e+00	619	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
650742460	225	56.65	48	219	1	170	5.0e-71	260	COG0225	Peptide methionine sulfoxide reductase MsrA	174
650742461	85	28.21	22	85	8	85	5.0e-06	42.6	COG5568	Uncharacterized protein	85
650742462	167	33.1	1	134	6	146	7.0e-21	93.5	COG0071	Molecular chaperone IbpA, HSP20 family	146
650742463	185	50.9	12	176	3	168	1.0e-49	189	COG0242	Peptide deformylase	168
650742464	301	51.47	1	298	2	307	8.0e-96	343	COG0223	Methionyl-tRNA formyltransferase	307
650742465	255	49.6	1	250	1	247	7.0e-80	290	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
650742466	156	67.31	1	156	18	173	1.0e-56	211	COG0290	Translation initiation factor IF-3	176
650742468	267	35.93	6	267	3	261	3.0e-64	238	COG0708	Exonuclease III	261
650742469	227	42.37	1	225	28	261	1.0e-59	222	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
650742470	251	44.18	5	251	2	242	5.0e-64	237	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
650742471	206	21.15	2	201	1	201	5.0e-21	94.7	COG2834	Outer membrane lipoprotein-sorting protein	211
650742473	463	38.22	5	444	4	473	9.0e-108	384	COG0260	Leucyl aminopeptidase	485
650742474	634	45.54	12	617	1	581	0.0e+00	612	COG0322	Excinuclease UvrABC, nuclease subunit	581
650742477	247	41.49	7	243	10	245	8.0e-56	210	COG1496	Copper oxidase (laccase) domain	249
650742478	324	37.69	16	324	35	369	9.0e-64	237	COG1565	SAM-dependent methyltransferase, MidA family	370
650742479	276	35.64	1	276	2	286	2.0e-57	215	COG0682	Prolipoprotein diacylglyceryltransferase	287
650742480	326	32.01	1	323	2	313	7.0e-38	151	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650742481	117	35.63	1	87	10	96	1.0e-09	55	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
650742482	197	39.39	1	197	3	192	3.0e-44	171	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
650742483	335	34.02	1	333	1	325	1.0e-57	217	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
650742484	241	30.22	16	240	4	223	8.0e-35	140	COG1451	Predicted metal-dependent hydrolase	223
650742485	158	59.06	1	149	3	151	4.0e-51	194	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
650742486	242	29.49	20	233	3	215	5.0e-27	114	COG2930	Lipid-binding SYLF domain	227
650742487	209	28.57	7	198	1	192	4.0e-25	107	COG0406	Broad specificity phosphatase PhoE	208
650742489	245	40.61	1	226	2	230	3.0e-57	215	COG1131	ABC-type multidrug transport system, ATPase component	293
650742491	381	54.32	16	374	21	368	5.0e-123	434	COG2021	Homoserine acetyltransferase	368
650742492	295	30.77	10	97	2	92	3.0e-09	56.1	COG1605	Chorismate mutase	101
650742493	364	42.13	7	359	2	351	1.0e-85	309	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
650742494	295	39.72	4	289	1	279	6.0e-69	254	COG0287	Prephenate dehydrogenase	279
650742495	311	37.94	5	311	2	269	7.0e-59	220	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
650742496	89	67.42	1	89	1	89	1.0e-26	111	COG0184	Ribosomal protein S15P/S13E	89
650742497	256	39.08	23	256	17	231	1.0e-29	123	COG0670	Integral membrane protein, interacts with FtsH	233
650742498	97	55.17	10	96	2	88	6.0e-21	92.2	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
650742499	140	38.21	1	120	1	123	2.0e-25	108	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
650742500	303	46.15	4	280	2	286	6.0e-79	287	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
650742502	227	44.59	1	226	1	229	7.0e-61	227	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650742503	464	29.5	134	452	21	335	4.0e-34	139	COG0642	Signal transduction histidine kinase	336
650742504	440	22.53	64	427	48	382	3.0e-10	60.2	COG2814	Predicted arabinose efflux permease, MFS family	394
650742505	904	23.46	344	904	5	577	3.0e-23	104	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
650742507	218	33.01	15	218	21	227	1.0e-34	140	COG4291	Uncharacterized membrane protein	228
650742508	547	48.34	8	545	4	532	0.0e+00	574	COG1069	Ribulose kinase	544
650742509	313	33.12	4	312	1	310	4.0e-45	175	COG0524	Sugar or nucleoside kinase, ribokinase family	311
650742510	284	26.44	11	212	5	206	3.0e-23	102	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
650742511	436	24.6	1	432	5	432	1.0e-39	157	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650742512	303	36.4	19	299	7	289	1.0e-46	180	COG1175	ABC-type sugar transport system, permease component	295
650742513	273	37.87	7	273	10	281	6.0e-45	174	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650742514	365	54.11	1	353	1	338	4.0e-123	434	COG3839	ABC-type sugar transport system, ATPase component	338
650742515	257	42.75	7	255	2	251	4.0e-48	185	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650742516	257	38.31	3	253	1	249	3.0e-37	149	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650742517	499	56.58	7	491	4	483	0.0e+00	686	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
650742518	604	40.36	8	603	4	571	0.0e+00	604	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
650742519	211	50.48	3	211	2	210	1.0e-53	202	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
650742520	447	21.63	12	426	20	387	3.0e-12	66.8	COG2814	Predicted arabinose efflux permease, MFS family	394
650742521	424	22.69	8	422	4	423	3.0e-23	103	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
650742522	211	47.97	1	147	1	146	1.0e-35	143	COG3427	Carbon monoxide dehydrogenase subunit G	146
650742523	300	27.39	1	290	6	284	8.0e-29	120	COG0714	MoxR-like ATPase	329
650742527	315	39.31	1	315	9	325	4.0e-70	258	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
650742528	260	38.31	3	257	2	250	7.0e-39	154	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650742529	245	73.47	1	245	1	245	5.0e-111	393	COG4689	Acetoacetate decarboxylase	247
650742530	382	23.23	18	363	5	306	3.0e-32	132	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
650742531	634	31.11	23	616	1	581	3.0e-99	356	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
650742534	313	32.41	22	309	5	281	6.0e-49	188	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
650742535	332	41.64	1	327	3	330	2.0e-81	296	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650742536	496	41.38	10	494	7	497	2.0e-108	386	COG1070	Sugar (pentulose or hexulose) kinase	502
650742537	331	29.34	1	331	1	321	6.0e-31	128	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650742538	501	44.4	12	498	9	495	0.0e+00	462	COG1129	ABC-type sugar transport system, ATPase component	500
650742539	336	41.14	14	327	2	314	1.0e-49	190	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650742540	89	38.2	1	89	2	90	7.0e-13	65.5	COG0776	Bacterial nucleoid DNA-binding protein	94
650742541	298	31.49	6	295	2	302	7.0e-36	144	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650742542	327	58.14	1	324	2	345	0.0e+00	497	COG1089	GDP-D-mannose dehydratase	345
650742543	748	38.09	13	744	7	728	5.0e-127	449	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
650742544	347	39.52	1	328	1	282	5.0e-51	195	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
650742545	165	62.58	4	157	3	155	3.0e-54	204	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
650742546	201	20.73	12	173	5	168	2.0e-06	45.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650742547	210	31.07	1	205	15	219	3.0e-27	115	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
650742548	302	27.11	14	283	1	262	9.0e-12	64.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650742549	204	32.37	1	165	8	180	3.0e-25	108	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
650742553	178	25.28	1	178	1	176	1.0e-27	115	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
650742554	680	35.59	265	636	10	408	3.0e-58	220	COG0840	Methyl-accepting chemotaxis protein	408
650742559	926	25.04	205	892	13	621	1.0e-63	238	COG1199	Rad3-related DNA helicase	654
650742560	211	30.37	3	210	14	200	3.0e-22	98.5	COG1573	Uracil-DNA glycosylase	202
650742561	190	37.43	7	181	6	177	6.0e-33	134	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
650742562	168	41.77	1	158	1	151	6.0e-32	130	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
650742563	136	43.84	1	71	1	73	2.0e-11	61.5	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
650742564	749	41.6	23	746	9	700	0.0e+00	747	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
650742565	134	46.56	1	131	1	126	2.0e-35	141	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
650742566	362	30.93	4	356	62	432	8.0e-53	201	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
650742567	524	50.48	14	425	1	409	4.0e-118	418	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
650742568	303	30.1	16	301	3	280	6.0e-22	98.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650742570	419	30.42	22	385	1	372	4.0e-49	188	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
650742571	446	34.35	1	445	2	443	2.0e-109	389	COG0174	Glutamine synthetase	443
650742572	358	41.44	1	356	2	360	3.0e-73	269	COG0687	Spermidine/putrescine-binding periplasmic protein	363
650742573	280	39.86	2	273	1	265	3.0e-45	175	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
650742574	310	38.16	25	307	9	286	6.0e-50	191	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
650742575	377	49.16	26	375	4	350	4.0e-108	385	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
650742576	371	67.39	1	371	1	371	0.0e+00	530	COG0686	Alanine dehydrogenase	371
650742578	458	47.11	9	453	4	449	0.0e+00	530	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
650742579	453	33.77	16	452	14	443	8.0e-96	344	COG0174	Glutamine synthetase	443
650742580	362	48.58	56	337	16	292	1.0e-75	276	COG1533	DNA repair photolyase	297
650742581	480	47.01	12	343	2	333	4.0e-112	398	COG0836	Mannose-1-phosphate guanylyltransferase	333
650742582	262	25.2	6	248	4	234	3.0e-21	95.4	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
650742584	231	42.98	1	225	4	229	1.0e-54	206	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
650742585	316	51.57	22	304	4	284	3.0e-92	331	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
650742586	547	33.58	9	542	4	550	4.0e-98	352	COG4987	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components	573
650742587	571	35.87	35	545	3	513	1.0e-97	350	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
650742588	278	54.42	1	278	1	282	1.0e-91	329	COG0414	Panthothenate synthetase	285
650742589	306	30	56	303	5	250	6.0e-29	121	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
650742592	588	41.06	15	588	30	602	0.0e+00	533	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
650742593	298	31.36	1	283	6	257	2.0e-27	116	COG0584	Glycerophosphoryl diester phosphodiesterase	257
650742594	348	41.39	24	346	11	341	5.0e-60	225	COG1566	Multidrug resistance efflux pump	352
650742596	519	35.48	23	518	1	453	2.0e-59	223	COG1538	Outer membrane protein TolC	457
650742597	337	26.35	14	330	2	332	2.0e-37	150	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
650742598	409	31.28	1	400	14	407	2.0e-121	429	COG0538	Isocitrate dehydrogenase	407
650742600	242	34.16	20	219	7	200	3.0e-35	141	COG0461	Orotate phosphoribosyltransferase	201
650742602	927	35.49	77	384	57	368	7.0e-51	196	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
650742603	758	24.79	91	563	1	431	3.0e-49	190	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
650742604	376	33.97	14	367	1	350	5.0e-53	201	COG3405	Endo-1,4-beta-D-glucanase Y	360
650742608	250	29.61	1	223	1	228	3.0e-27	115	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650742609	235	40.21	29	214	28	213	9.0e-29	120	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
650742610	240	47.86	6	237	3	228	2.0e-53	202	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650742615	484	46.36	149	478	4	332	3.0e-93	336	COG3800	Predicted transcriptional regulator	332
650742616	379	30.5	14	378	1	363	6.0e-63	235	COG1195	Recombinational DNA repair ATPase RecF	363
650742617	309	44.3	3	307	2	304	5.0e-82	297	COG0196	FAD synthase	304
650742618	166	35.1	6	148	3	153	9.0e-20	89.8	COG2030	Acyl dehydratase	159
650742619	310	20.31	6	259	3	255	2.0e-10	60.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
650742621	491	19.53	8	322	2	344	2.0e-13	70.6	COG2814	Predicted arabinose efflux permease, MFS family	394
650742622	579	40.07	12	578	5	567	1.0e-119	424	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650742626	358	28.22	12	330	2	311	2.0e-36	146	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650742627	183	43.1	1	174	1	171	2.0e-46	178	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
650742630	280	30.19	3	255	2	262	6.0e-26	111	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650742631	256	34.92	4	254	7	236	7.0e-66	244	COG3510	Cephalosporin hydroxylase	237
650742632	537	30.6	176	516	41	406	4.0e-38	153	COG0840	Methyl-accepting chemotaxis protein	408
650742633	184	34.64	28	175	50	202	8.0e-25	107	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
650742635	273	24.73	68	249	69	235	3.0e-07	49.2	COG5031	Ubiquinone biosynthesis protein Coq4	235
650742636	317	32.89	7	310	8	305	4.0e-43	168	COG0650	Formate hydrogenlyase subunit 4	309
650742637	226	24.27	22	226	16	218	4.0e-10	58.7	COG4237	Hydrogenase-4 membrane subunit HyfE	218
650742638	506	31.81	1	468	2	474	3.0e-48	186	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
650742639	478	34.72	125	478	10	367	2.0e-69	256	COG3261	Ni,Fe-hydrogenase III large subunit	382
650742640	264	47.86	122	260	3	142	2.0e-43	169	COG3260	Ni,Fe-hydrogenase III small subunit	148
650742641	658	27.27	5	482	7	475	4.0e-29	123	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
650742642	115	37.86	1	103	1	102	3.0e-20	90.3	COG1993	PII-like signaling protein	109
650742643	138	46.6	6	108	5	107	2.0e-28	118	COG1993	PII-like signaling protein	109
650742644	301	44.6	5	291	2	277	2.0e-74	272	COG1091	dTDP-4-dehydrorhamnose reductase	281
650742645	184	50.28	1	177	2	173	4.0e-55	207	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
650742646	293	54.55	3	288	1	283	2.0e-101	362	COG1209	dTDP-glucose pyrophosphorylase	286
650742647	331	54.49	6	328	27	337	1.0e-127	449	COG1088	dTDP-D-glucose 4,6-dehydratase	340
650742651	384	44.65	8	383	9	390	1.0e-109	390	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
650742653	251	24.28	1	236	4	244	5.0e-24	105	COG1381	Recombinational DNA repair protein (RecF pathway)	251
650742654	744	42.3	3	732	2	739	0.0e+00	748	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
650742655	688	20.99	35	652	14	618	4.0e-21	97	COG1289	Uncharacterized membrane protein YccC	674
650742656	175	42.24	15	175	6	165	3.0e-26	111	COG2862	Uncharacterized membrane protein YqhA	169
650742658	514	46.97	7	513	5	485	0.0e+00	487	COG0260	Leucyl aminopeptidase	485
650742659	256	46.39	6	256	8	267	3.0e-64	238	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
650742660	298	37.66	1	295	5	305	1.0e-52	200	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
650742661	121	33.78	32	104	5	78	1.0e-11	61.8	COG0425	TusA-related sulfurtransferase	78
650742662	309	46.15	1	307	2	310	1.0e-81	296	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
650742663	88	42.42	15	80	5	70	5.0e-09	53	COG1722	Exonuclease VII small subunit	81
650742664	301	39.58	10	293	3	279	5.0e-56	211	COG0142	Geranylgeranyl pyrophosphate synthase	322
650742666	205	37.77	14	199	10	197	4.0e-35	141	COG3548	Uncharacterized membrane protein	197
650742667	382	36.64	1	382	149	528	8.0e-86	310	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650742671	499	30.91	268	487	1	169	6.0e-32	132	COG0516	IMP dehydrogenase/GMP reductase	170
650742672	426	38.1	99	426	20	355	3.0e-70	259	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
650742673	177	24.05	1	153	11	154	2.0e-06	45.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
650742674	313	37.25	20	311	12	300	1.0e-61	230	COG4974	Site-specific recombinase XerD	300
650742675	137	27.07	1	133	2	133	2.0e-20	91.4	COG0848	Biopolymer transport protein ExbD	137
650742676	223	29	7	201	13	212	3.0e-22	98.9	COG0811	Biopolymer transport protein ExbB/TolQ	216
650742677	607	45.57	1	312	1	314	8.0e-99	354	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
650742678	287	41.27	29	279	27	278	3.0e-49	188	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
650742679	314	43.63	1	314	4	316	2.0e-73	269	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
650742680	544	25.63	5	537	16	554	9.0e-51	195	COG0747	ABC-type transport system, periplasmic component	556
650742681	249	35.68	68	246	56	240	2.0e-09	56.3	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
650742682	289	55.8	7	281	11	283	1.0e-102	366	COG2607	Predicted ATPase, AAA+ superfamily	287
650742683	119	34.38	14	109	2	95	6.0e-18	82.9	COG1862	Preprotein translocase subunit YajC	97
650742684	201	49.5	1	200	2	198	5.0e-60	223	COG0605	Superoxide dismutase	204
650742685	236	24.66	1	211	8	225	1.0e-12	66.9	COG1562	Phytoene/squalene synthetase	288
650742686	910	48.77	7	900	1	804	0.0e+00	939	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
650742687	169	48.43	7	165	4	157	7.0e-54	203	COG0669	Phosphopantetheine adenylyltransferase	159
650742688	184	45.28	34	184	1	158	3.0e-42	164	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
650742692	307	27.33	9	307	2	291	9.0e-27	114	COG0583	DNA-binding transcriptional regulator, LysR family	297
650742693	307	26.82	4	299	3	267	4.0e-28	118	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
650742694	414	34.79	21	414	12	408	2.0e-50	193	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
650742695	431	26.7	46	417	31	406	9.0e-32	131	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
650742696	439	55.61	17	433	8	422	6.0e-129	454	COG2379	Glycerate-2-kinase	422
650742697	292	50.35	1	284	1	286	4.0e-80	291	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
650742698	268	58.89	1	253	1	253	1.0e-98	353	COG3622	Hydroxypyruvate isomerase	260
650742699	594	76.9	1	593	1	590	0.0e+00	999	COG3960	Glyoxylate carboligase	592
650742700	306	38.26	6	297	1	293	4.0e-30	125	COG0583	DNA-binding transcriptional regulator, LysR family	297
650742701	518	49.9	1	500	4	483	0.0e+00	504	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
650742702	812	59.21	31	811	6	780	0.0e+00	1038	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
650742703	290	29.96	4	268	11	266	6.0e-27	115	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
650742704	116	46.55	1	115	8	123	9.0e-31	125	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
650742705	399	43.52	1	399	1	405	1.0e-106	380	COG3748	Uncharacterized membrane protein	407
650742706	180	49.11	1	165	1	168	1.0e-33	135	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
650742707	462	26.46	16	453	4	436	6.0e-40	158	COG1457	Purine-cytosine permease or related protein	442
650742708	486	35.89	37	435	22	407	3.0e-76	279	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
650742709	479	57.2	1	475	11	488	0.0e+00	684	COG0753	Catalase	496
650742711	326	37.42	1	326	5	326	6.0e-67	247	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
650742712	277	38.52	15	270	1	253	2.0e-51	196	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
650742713	374	25.73	8	368	6	410	5.0e-23	102	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
650742714	350	49.56	5	343	4	329	4.0e-95	341	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
650742715	363	26.3	50	329	29	314	2.0e-23	103	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650742716	524	50.2	16	518	3	500	0.0e+00	548	COG1129	ABC-type sugar transport system, ATPase component	500
650742717	334	36.74	13	324	2	312	1.0e-46	180	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650742718	328	37.1	20	327	3	310	1.0e-39	156	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650742719	254	57.49	5	251	2	237	5.0e-99	354	COG1126	ABC-type polar amino acid transport system, ATPase component	240
650742720	250	43.1	1	232	1	220	7.0e-55	207	COG0765	ABC-type amino acid transport system, permease component	222
650742721	274	31.77	7	273	1	271	6.0e-29	121	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650742722	391	25	34	391	9	367	2.0e-25	110	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
650742723	504	27.04	7	499	1	448	1.0e-52	200	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
650742724	324	41.1	14	305	2	293	4.0e-65	241	COG1230	Co/Zn/Cd efflux system component	296
650742726	131	36.04	4	113	3	113	2.0e-18	85.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
650742728	92	46.15	1	91	1	89	1.0e-16	78.3	COG1937	DNA-binding transcriptional regulator, FrmR family	89
650742729	198	56.13	45	198	2	156	5.0e-50	190	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
650742730	781	36.65	44	773	5	731	2.0e-121	430	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
650742731	338	29.74	1	338	1	281	3.0e-36	146	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
650742732	349	30.06	6	340	2	335	1.0e-44	174	COG0673	Predicted dehydrogenase	342
650742733	338	30.03	7	327	12	315	6.0e-23	101	COG0530	Ca2+/Na+ antiporter	320
650742734	885	42.75	16	878	20	915	0.0e+00	808	COG0474	Magnesium-transporting ATPase (P-type)	917
650742735	132	36.97	1	119	2	120	2.0e-20	91.4	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
650742736	231	50.53	35	221	8	194	1.0e-63	236	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
650742737	592	55.53	195	592	1	398	0.0e+00	565	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
650742738	165	42.04	9	165	1	157	6.0e-48	183	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
650742739	434	51.1	15	422	19	423	0.0e+00	505	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
650742740	902	31.96	1	776	1	693	0.0e+00	499	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
650742741	335	56.35	19	334	11	332	6.0e-93	334	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
650742742	170	43.79	5	155	16	163	1.0e-39	156	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
650742743	166	35	1	160	4	163	3.0e-11	61.8	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
650742744	102	46.46	4	102	2	100	1.0e-18	84.4	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
650742745	618	44.62	5	614	1	606	1.0e-115	411	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
650742746	505	49.3	1	497	4	493	0.0e+00	461	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
650742747	486	41.05	11	485	5	473	3.0e-73	269	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
650742752	304	32.65	20	296	5	293	1.0e-24	107	COG0583	DNA-binding transcriptional regulator, LysR family	297
650742753	359	36	7	329	4	316	5.0e-50	191	COG0385	Predicted Na+-dependent transporter	319
650742755	334	38.68	17	259	1	230	5.0e-49	188	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
650742756	689	43.5	54	626	5	566	0.0e+00	487	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
650742757	204	33.68	15	204	23	209	1.0e-25	109	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
650742759	203	33.71	22	198	1	176	1.0e-15	76.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650742760	224	30.19	1	211	1	212	3.0e-09	55.7	COG4944	Uncharacterized protein	213
650742761	531	26.78	18	529	18	433	1.0e-111	397	COG2224	Isocitrate lyase	433
650742762	227	26.4	1	176	3	180	1.0e-05	43.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650742763	499	31.7	11	435	2	423	2.0e-79	290	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
650742764	286	32.55	5	259	4	248	1.0e-37	150	COG0300	Short-chain dehydrogenase	265
650742765	305	41.64	43	301	46	312	2.0e-38	153	COG0657	Acetyl esterase/lipase	312
650742766	537	22.94	79	537	22	468	7.0e-44	172	COG5338	Uncharacterized protein	468
650742770	420	22.78	107	363	47	250	2.0e-20	93.9	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
650742771	475	20.6	69	469	50	391	1.0e-11	64.8	COG2814	Predicted arabinose efflux permease, MFS family	394
650742775	378	21.77	57	371	1	311	1.0e-26	114	COG0668	Small-conductance mechanosensitive channel	316
650742777	312	31.25	1	310	4	323	3.0e-33	135	COG0306	Phosphate/sulfate permease	326
650742778	248	28.95	46	232	1	184	2.0e-33	135	COG0431	NAD(P)H-dependent FMN reductase	184
650742779	317	35.53	1	317	1	315	4.0e-34	138	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650742780	818	39.64	22	500	9	500	3.0e-116	413	COG1129	ABC-type sugar transport system, ATPase component	500
650742781	347	25.62	1	321	1	316	4.0e-31	129	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650742783	491	31.46	36	478	2	411	9.0e-55	208	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
650742784	421	36.92	1	418	11	421	5.0e-98	351	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
650742785	251	35.12	4	243	1	241	1.0e-38	153	COG2186	DNA-binding transcriptional regulator, FadR family	241
650742786	230	36.63	55	226	45	204	1.0e-23	103	COG5618	Predicted periplasmic lipoprotein	206
650742787	504	46.92	1	500	4	500	0.0e+00	540	COG1129	ABC-type sugar transport system, ATPase component	500
650742788	365	45.92	23	352	1	314	5.0e-59	221	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650742789	328	36.7	1	323	3	319	2.0e-42	166	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650742790	351	33.82	1	332	3	335	1.0e-48	187	COG0673	Predicted dehydrogenase	342
650742791	558	33.74	15	248	26	268	9.0e-11	62.3	COG0457	Tetratricopeptide (TPR) repeat	291
650742792	582	29.73	281	563	2	296	9.0e-22	98.7	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
650742793	276	45.96	65	254	1	197	5.0e-41	161	COG1573	Uracil-DNA glycosylase	202
650742794	544	32.59	10	456	1	396	3.0e-69	256	COG0644	Dehydrogenase (flavoprotein)	396
650742795	157	22.37	1	139	8	157	2.0e-07	48.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
650742796	247	39.55	4	247	1	266	3.0e-58	218	COG0289	Dihydrodipicolinate reductase	266
650742797	395	54.41	4	394	2	387	0.0e+00	542	COG0192	S-adenosylmethionine synthetase	388
650742798	225	28.38	13	225	9	225	5.0e-35	141	COG0220	tRNA G46 methylase TrmB	227
650742799	417	29.13	32	385	3	356	9.0e-53	201	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650742800	289	34.97	9	286	10	294	6.0e-36	144	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650742801	328	35.99	24	328	5	314	7.0e-44	171	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
650742802	254	48.59	1	247	2	250	3.0e-77	281	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650742803	236	52.97	3	232	2	237	1.0e-80	292	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650742804	405	22.98	9	401	1	394	4.0e-11	62.9	COG2814	Predicted arabinose efflux permease, MFS family	394
650742805	617	54.38	1	613	8	575	0.0e+00	759	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
650742808	327	25.55	5	321	2	321	4.0e-36	145	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
650742809	316	27.92	16	294	2	261	4.0e-16	79	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650742810	384	40.8	8	374	1	366	3.0e-95	342	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
650742811	633	40.62	14	621	3	578	0.0e+00	473	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
650742812	1270	59.28	509	1270	1	769	0.0e+00	882	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
650742813	878	55.42	1	876	5	875	0.0e+00	1126	COG0013	Alanyl-tRNA synthetase	879
650742817	343	67.49	1	280	5	279	3.0e-89	321	COG0468	RecA/RadA recombinase	279
650742818	341	38.14	8	337	2	308	1.0e-58	220	COG2017	Galactose mutarotase or related enzyme	308
650742819	547	29.97	69	440	22	390	1.0e-40	161	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650742823	64	33.93	3	58	18	73	2.0e-07	47.7	COG0690	Preprotein translocase subunit SecE	73
650742824	176	53.67	1	176	1	177	1.0e-50	192	COG0250	Transcription antitermination factor NusG	178
650742825	300	26.8	6	292	1	282	6.0e-17	81.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650742826	140	29.03	19	140	36	157	2.0e-08	51.6	COG2030	Acyl dehydratase	159
650742827	262	54.05	1	258	29	286	6.0e-96	344	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
650742828	472	35.56	19	458	13	459	7.0e-93	334	COG1109	Phosphomannomutase	464
650742829	333	47.63	1	311	5	314	5.0e-95	341	COG0180	Tryptophanyl-tRNA synthetase	314
650742830	510	44.31	1	493	9	508	3.0e-90	326	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
650742832	229	23.29	7	206	13	227	3.0e-11	62.4	COG2365	Protein tyrosine/serine phosphatase	249
650742834	280	44.16	6	272	5	273	2.0e-51	196	COG2890	Methylase of polypeptide chain release factors	280
650742835	352	58.56	1	351	3	361	4.0e-130	458	COG0216	Protein chain release factor A	363
650742836	411	47.53	1	410	1	424	1.0e-125	443	COG0124	Histidyl-tRNA synthetase	429
650742837	374	56.79	9	369	1	361	0.0e+00	486	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
650742838	437	22.89	27	269	3	241	1.0e-21	98.2	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
650742839	755	40.29	18	755	2	750	0.0e+00	560	COG3605	Signal transduction protein containing GAF and PtsI domains	756
650742840	345	34.12	15	336	11	336	6.0e-46	178	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
650742841	405	44.69	1	403	1	447	2.0e-115	409	COG0527	Aspartokinase	447
650742842	249	46.96	17	246	11	239	2.0e-64	239	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
650742843	317	29.53	15	306	3	297	2.0e-28	120	COG0583	DNA-binding transcriptional regulator, LysR family	297
650742844	518	31.95	14	459	1	467	1.0e-62	234	COG3119	Arylsulfatase A or related enzyme	475
650742845	351	40.79	8	337	2	328	1.0e-74	273	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
650742846	423	27.21	21	423	4	366	7.0e-59	221	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
650742847	363	35.87	28	303	8	266	7.0e-59	221	COG1018	Ferredoxin-NADP reductase	266
650742848	324	44.58	1	322	1	323	2.0e-81	296	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
650742849	678	36.31	6	369	4	363	2.0e-86	313	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
650742850	615	27.41	224	607	2	386	1.0e-56	214	COG0247	Fe-S oxidoreductase	388
650742851	358	32.27	57	356	3	312	1.0e-38	153	COG2025	Electron transfer flavoprotein, alpha subunit	313
650742853	456	49.65	171	452	1	262	1.0e-77	284	COG1760	L-serine deaminase	262
650742854	186	37.43	1	184	4	187	6.0e-29	120	COG4583	Sarcosine oxidase gamma subunit	189
650742855	998	40.51	605	998	2	379	3.0e-106	379	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
650742856	84	57.69	1	78	1	78	4.0e-26	109	COG4311	Sarcosine oxidase delta subunit	97
650742857	417	31.06	29	407	1	387	2.0e-55	209	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
650742858	552	53.21	1	536	4	541	0.0e+00	489	COG2303	Choline dehydrogenase or related flavoprotein	542
650742859	487	51.77	7	482	2	471	0.0e+00	487	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650742860	417	43.92	6	401	4	386	2.0e-109	389	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
650742861	286	53.18	14	280	9	274	2.0e-83	302	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
650742862	314	32.67	1	300	3	302	3.0e-65	242	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
650742863	113	47.57	6	108	3	105	2.0e-19	87.4	COG2076	Multidrug transporter EmrE and related cation transporters	106
650742865	366	30.71	61	321	1	259	7.0e-32	131	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
650742866	288	45.85	13	287	6	282	2.0e-56	212	COG4132	ABC-type uncharacterized transport system, permease component	282
650742867	260	24.6	12	253	15	264	7.0e-23	101	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
650742868	353	49.58	1	352	3	352	9.0e-108	383	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
650742869	262	38.31	7	258	5	260	3.0e-40	158	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
650742870	282	32.64	1	279	1	277	5.0e-30	125	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
650742871	301	28.43	27	128	20	121	9.0e-11	61.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
650742873	258	22.33	8	220	4	210	5.0e-18	84.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
650742874	210	22.93	1	203	11	215	3.0e-10	58.8	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
650742876	337	26.54	16	337	5	324	6.0e-40	158	COG1868	Flagellar motor switch protein FliM	332
650742877	511	47.07	1	510	3	548	0.0e+00	623	COG0143	Methionyl-tRNA synthetase	558
650742879	210	43.96	4	208	2	208	2.0e-52	198	COG0125	Thymidylate kinase	208
650742881	319	43.71	6	317	20	335	7.0e-68	251	COG2951	Membrane-bound lytic murein transglycosylase B	343
650742882	220	40.76	8	216	5	215	1.0e-48	186	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
650742884	606	65.28	124	579	3	432	0.0e+00	726	COG0422	Thiamine biosynthesis protein ThiC	432
650742885	373	33.33	1	372	5	387	5.0e-40	158	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
650742886	68	49.23	6	68	5	68	7.0e-09	52.1	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
650742887	255	57.81	1	254	5	260	1.0e-85	309	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
650742888	135	30.19	27	131	1	106	9.0e-09	52.9	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650742891	289	28.04	1	208	8	211	1.0e-23	103	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650742892	433	54.46	1	433	1	426	0.0e+00	540	COG0172	Seryl-tRNA synthetase	429
650742893	268	45.67	13	266	1	248	8.0e-61	227	COG0805	Sec-independent protein secretion pathway component TatC	255
650742894	147	37.31	1	67	1	67	2.0e-10	58	COG1826	Sec-independent protein translocase protein TatA	94
650742895	185	44.51	14	173	10	172	1.0e-37	149	COG1386	Chromosome segregation and condensation protein ScpB	184
650742896	264	35.57	13	262	1	245	9.0e-37	147	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
650742897	231	36.68	6	200	13	205	2.0e-12	66.2	COG1994	Zn-dependent protease (includes SpoIVFB)	230
650742898	308	38.71	1	303	5	306	1.0e-54	207	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
650742900	596	36.01	3	595	1	577	0.0e+00	482	COG0018	Arginyl-tRNA synthetase	577
650742901	380	45.41	3	376	9	411	2.0e-95	343	COG0232	dGTP triphosphohydrolase	412
650742902	113	52.88	10	112	7	110	1.0e-31	128	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
650742903	256	44.06	1	256	1	261	7.0e-77	280	COG0708	Exonuclease III	261
650742904	534	41.12	5	534	1	485	0.0e+00	491	COG2509	Uncharacterized FAD-dependent dehydrogenase	486
650742905	624	41.31	26	518	1	528	0.0e+00	467	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
650742906	156	25.62	35	155	22	141	4.0e-08	50.9	COG3431	Uncharacterized membrane protein, DUF373 family	142
650742907	312	43.14	15	310	14	310	8.0e-57	214	COG0657	Acetyl esterase/lipase	312
650742908	225	45.05	4	224	1	222	3.0e-69	254	COG1136	ABC-type lipoprotein export system, ATPase component	226
650742909	415	39.95	1	415	1	408	8.0e-95	340	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
650742910	437	42.48	1	435	1	498	0.0e+00	465	COG0442	Prolyl-tRNA synthetase	500
650742911	364	26.91	1	364	9	380	5.0e-18	85.6	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
650742912	548	37.93	5	546	6	555	0.0e+00	517	COG0595	mRNA degradation ribonuclease J1/J2	555
650742913	266	45.67	1	253	1	251	4.0e-64	238	COG1521	Pantothenate kinase type III	251
650742914	242	37.82	13	241	1	235	4.0e-40	158	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
650742915	482	47.27	4	477	1	475	4.0e-97	348	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
650742916	505	50.3	1	494	1	492	0.0e+00	473	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
650742917	642	45.07	3	637	1	606	1.0e-127	450	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
650742918	103	55.45	3	103	1	100	9.0e-20	88.2	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
650742919	216	47.31	1	167	2	163	3.0e-27	115	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
650742920	163	46.39	3	163	1	161	3.0e-44	171	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
650742921	338	55.29	5	334	3	332	5.0e-97	347	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
650742922	686	50.51	1	675	1	679	0.0e+00	714	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
650742923	431	56.5	1	421	5	424	0.0e+00	626	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
650742924	203	45.24	7	167	1	159	2.0e-46	178	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
650742925	406	59.33	21	406	13	398	0.0e+00	595	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
650742926	213	49.06	29	186	21	176	1.0e-40	159	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
650742927	186	62.5	18	185	1	168	5.0e-75	273	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
650742928	121	51.24	1	121	1	121	9.0e-30	122	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
650742931	87	58.14	2	87	6	91	2.0e-21	94	COG0776	Bacterial nucleoid DNA-binding protein	94
650742932	813	67.73	15	791	2	782	0.0e+00	1187	COG0466	ATP-dependent Lon protease, bacterial type	782
650742933	418	71.46	15	415	1	403	0.0e+00	698	COG1219	ATP-dependent protease Clp, ATPase subunit	408
650742934	209	71.28	12	206	2	196	2.0e-82	298	COG0740	ATP-dependent protease ClpP, protease subunit	200
650742935	440	39.5	1	439	1	441	4.0e-92	332	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
650742937	658	25.43	13	319	7	333	8.0e-22	99.4	COG3240	Phospholipase/lecithinase/hemolysin	370
650742938	938	39.89	68	928	18	862	0.0e+00	712	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
650742939	882	41.89	7	866	4	841	0.0e+00	739	COG0249	DNA mismatch repair ATPase MutS	843
650742940	447	54.81	74	447	3	364	0.0e+00	512	COG0505	Carbamoylphosphate synthase small subunit	368
650742941	1081	69.87	13	407	1	393	0.0e+00	561	COG0458	Carbamoylphosphate synthase large subunit	400
650742942	157	50.99	6	156	1	150	5.0e-41	160	COG0782	Transcription elongation factor, GreA/GreB family	151
650742943	398	49.27	1	335	6	346	6.0e-87	314	COG1171	Threonine dehydratase	347
650742944	401	40.8	6	399	3	384	6.0e-95	341	COG2309	Leucyl aminopeptidase (aminopeptidase T)	385
650742945	267	25.09	1	264	2	263	6.0e-34	137	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
650742946	257	46.67	1	253	2	254	2.0e-76	279	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
650742947	505	54.22	1	503	2	507	0.0e+00	625	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
650742948	392	23.06	4	383	11	416	7.0e-26	111	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
650742949	463	40.73	13	386	3	381	2.0e-96	346	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
650742950	321	29.25	72	315	5	244	7.0e-23	101	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
650742951	164	22.42	1	162	1	157	4.0e-09	54.6	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
650742952	223	35	17	221	17	233	1.0e-37	149	COG0412	Dienelactone hydrolase	236
650742953	520	69.5	203	520	2	315	0.0e+00	533	COG0519	GMP synthase, PP-ATPase domain/subunit	315
650742954	404	20.94	102	370	17	281	3.0e-08	53.7	COG4974	Site-specific recombinase XerD	300
650742956	157	33.33	25	154	1	132	7.0e-15	73.5	COG3335	Transposase	132
650742957	128	36.8	1	123	1	124	2.0e-12	65	COG3415	Transposase	138
650742958	346	31.21	4	329	1	303	4.0e-28	118	COG3547	Transposase	303
650742959	577	19.02	67	479	10	432	9.0e-26	112	COG5421	Transposase	480
650742961	423	30.79	25	391	18	358	1.0e-47	184	COG3328	Transposase (or an inactivated derivative)	379
650742964	275	30.71	17	139	1	124	2.0e-12	66.7	COG3293	Transposase	124
650742966	182	30.71	17	139	1	124	5.0e-12	64.4	COG3293	Transposase	124
650742976	775	16.84	16	751	33	757	4.0e-28	120	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
650742978	252	36.29	13	248	8	238	3.0e-22	98.9	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
650742979	557	46.76	70	553	2	493	0.0e+00	501	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
650742980	406	35.91	1	401	1	392	1.0e-72	267	COG1459	Type II secretory pathway, component PulF	397
650742981	155	28.31	17	154	8	172	4.0e-08	51.2	COG4970	Tfp pilus assembly protein FimT	181
650742983	198	20.34	1	118	4	114	2.0e-05	42.3	COG2165	Type II secretory pathway, pseudopilin PulG	149
650742987	758	24.45	206	730	60	568	4.0e-56	213	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
650742988	265	22.22	6	212	2	235	5.0e-06	45	COG3156	Type II secretory pathway, component PulK	323
650742989	163	33.6	25	140	3	127	7.0e-12	63.5	COG2165	Type II secretory pathway, pseudopilin PulG	149
650743000	178	47.1	33	169	13	147	6.0e-33	133	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
650743003	158	39.85	18	149	3	135	4.0e-29	120	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
650743004	95	48.42	1	95	1	95	6.0e-22	95.7	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
650743005	493	53.64	1	485	2	473	0.0e+00	481	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
650743006	487	55.19	7	484	1	482	0.0e+00	685	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
650743007	229	33.94	2	217	4	207	1.0e-31	129	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
650743008	126	38.14	27	123	14	101	1.0e-05	41.9	COG2863	Cytochrome c553	121
650743009	144	33.58	1	134	4	140	6.0e-20	90	COG2847	Copper(I)-binding protein	151
650743010	214	29.5	11	209	12	206	8.0e-30	123	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
650743011	505	22.27	1	408	1	419	1.0e-15	78.2	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
650743012	236	34.42	3	212	13	227	8.0e-30	123	COG1877	Trehalose-6-phosphatase	266
650743013	457	41.7	1	455	14	480	2.0e-123	435	COG0380	Trehalose-6-phosphate synthase	486
650743016	638	57	333	637	38	342	1.0e-94	341	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
650743017	609	38.49	3	500	2	497	2.0e-103	369	COG0358	DNA primase (bacterial type)	568
650743018	156	38.93	6	154	3	148	1.0e-27	115	COG1610	Uncharacterized conserved protein YqeY	148
650743021	408	36.48	32	408	1	392	2.0e-77	283	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650743022	510	41.23	18	469	21	492	3.0e-114	405	COG0513	Superfamily II DNA and RNA helicase	513
650743023	235	25.94	6	230	5	235	1.0e-05	43.5	COG3471	Predicted secreted (periplasmic) protein	235
650743024	494	18.1	151	470	58	376	1.0e-17	84.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650743025	441	30.95	165	441	37	329	4.0e-31	129	COG0642	Signal transduction histidine kinase	336
650743026	231	44.1	7	231	2	229	3.0e-51	195	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650743027	177	28.12	48	143	14	109	8.0e-09	53.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
650743028	299	39.44	10	288	1	281	5.0e-62	231	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
650743029	129	29.17	3	122	13	119	7.0e-09	53	COG2149	Uncharacterized membrane protein YidH, DUF202 family	120
650743030	404	22.07	44	398	37	383	1.0e-10	61.4	COG2814	Predicted arabinose efflux permease, MFS family	394
650743031	246	45.27	4	238	5	240	9.0e-64	237	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
650743033	289	56.99	1	284	1	286	3.0e-108	385	COG0777	Acetyl-CoA carboxylase beta subunit	294
650743034	435	43.39	8	427	2	420	7.0e-100	358	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
650743035	357	37.11	3	352	2	335	2.0e-66	246	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
650743036	299	30.85	1	293	2	292	3.0e-30	125	COG0583	DNA-binding transcriptional regulator, LysR family	297
650743037	157	41.94	1	155	2	155	7.0e-41	159	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
650743038	516	54.78	92	508	1	418	0.0e+00	571	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
650743039	946	45.92	15	941	1	965	0.0e+00	1235	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
650743040	275	39.52	19	266	18	264	4.0e-57	215	COG1526	Formate dehydrogenase assembly factor FdhD	266
650743042	274	33.33	1	258	3	257	2.0e-33	136	COG2116	Formate/nitrite transporter FocA, FNT family	265
650743043	111	34.31	5	101	2	103	1.0e-10	58.1	COG5447	Uncharacterized protein	115
650743044	336	23.51	9	335	7	332	5.0e-24	105	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
650743045	246	51.03	1	242	3	243	9.0e-76	276	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
650743046	254	36.61	1	252	7	256	9.0e-35	140	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
650743048	278	65.49	14	268	3	257	3.0e-111	394	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
650743049	195	59.47	6	195	25	214	1.0e-72	265	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
650743050	427	28.47	1	426	6	421	7.0e-59	221	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
650743051	225	58.8	5	219	2	215	5.0e-80	290	COG0036	Pentose-5-phosphate-3-epimerase	220
650743053	142	39.02	1	123	6	121	2.0e-32	131	COG4451	Ribulose bisphosphate carboxylase small subunit	127
650743054	493	47.6	22	476	1	429	0.0e+00	521	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
650743055	359	40.61	1	329	1	286	3.0e-92	332	COG0191	Fructose/tagatose bisphosphate aldolase	286
650743056	291	55.17	1	290	1	289	3.0e-119	421	COG3954	Phosphoribulokinase	289
650743057	355	44.74	27	328	25	323	3.0e-88	318	COG0158	Fructose-1,6-bisphosphatase	326
650743059	140	55.97	1	134	4	137	1.0e-40	158	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
650743060	272	49.42	5	260	5	259	3.0e-73	268	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
650743061	456	46.12	4	453	1	460	4.0e-116	411	COG1109	Phosphomannomutase	464
650743062	278	46.21	16	276	7	265	2.0e-60	226	COG0294	Dihydropteroate synthase	274
650743064	338	27.78	65	316	50	312	1.0e-23	104	COG0657	Acetyl esterase/lipase	312
650743065	219	25.12	12	209	5	209	3.0e-13	68.7	COG0625	Glutathione S-transferase	211
650743066	214	27.55	15	202	4	198	1.0e-34	139	COG1573	Uracil-DNA glycosylase	202
650743067	95	51.58	1	95	2	96	5.0e-27	112	COG2154	Pterin-4a-carbinolamine dehydratase	101
650743068	468	25.8	6	468	1	408	6.0e-49	188	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
650743069	199	34.02	17	197	21	213	3.0e-28	118	COG4619	ABC-type iron transport system FetAB, ATPase component	223
650743070	263	38.91	1	257	1	252	8.0e-42	164	COG0390	ABC-type iron transport system FetAB, permease component	256
650743071	641	25.99	13	617	9	620	2.0e-65	244	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
650743073	568	26.55	146	414	77	331	6.0e-33	136	COG0642	Signal transduction histidine kinase	336
650743074	337	27.6	61	335	99	373	4.0e-23	102	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650743077	384	53.06	26	384	9	365	3.0e-107	382	COG1706	Flagellar basal body P-ring protein FlgI	365
650743079	138	55	18	137	1	120	9.0e-27	112	COG1734	RNA polymerase-binding transcription factor DksA	120
650743080	682	50.59	9	676	2	665	0.0e+00	799	COG0272	NAD-dependent DNA ligase	667
650743081	559	43.73	1	557	1	553	0.0e+00	472	COG0497	DNA repair ATPase RecN	557
650743082	315	38.31	38	298	4	253	7.0e-59	220	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
650743083	575	52.45	18	563	1	541	0.0e+00	577	COG0539	Ribosomal protein S1	541
650743085	222	29.22	1	217	2	211	7.0e-17	80.8	COG4649	Uncharacterized protein	221
650743087	451	48.08	8	450	3	444	0.0e+00	530	COG1160	Predicted GTPases	444
650743090	409	58.52	5	407	3	403	0.0e+00	584	COG0137	Argininosuccinate synthase	403
650743091	200	27.05	48	168	8	127	4.0e-11	61.5	COG0526	Thiol-disulfide isomerase or thioredoxin	127
650743092	481	58.59	28	481	6	458	0.0e+00	596	COG0165	Argininosuccinate lyase	459
650743093	438	45.11	19	411	1	394	8.0e-97	347	COG0019	Diaminopimelate decarboxylase	394
650743095	269	43.36	1	256	1	245	1.0e-79	289	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
650743096	293	31.32	31	293	2	263	3.0e-36	146	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
650743098	400	48.4	7	400	2	393	8.0e-116	410	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
650743099	628	29.7	26	591	94	649	2.0e-115	410	COG0209	Ribonucleotide reductase alpha subunit	696
650743100	338	31.49	4	334	3	342	1.0e-80	293	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
650743103	266	39.18	1	262	1	268	2.0e-44	172	COG0388	Predicted amidohydrolase	274
650743105	223	40.44	1	223	2	211	4.0e-35	141	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
650743106	311	47.76	1	303	3	310	5.0e-99	354	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
650743107	428	40.76	7	427	2	420	3.0e-97	349	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
650743108	192	46.94	1	188	4	199	6.0e-38	150	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
650743109	373	38.27	1	367	3	347	2.0e-83	302	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
650743110	891	47.58	2	572	1	556	0.0e+00	614	COG0550	DNA topoisomerase IA	570
650743111	358	46.34	1	353	5	370	9.0e-78	284	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
650743113	417	47.37	3	416	1	400	3.0e-125	441	COG0162	Tyrosyl-tRNA synthetase	401
650743114	145	44.59	1	144	1	140	2.0e-31	128	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
650743115	347	28.33	37	324	4	289	1.0e-23	104	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
650743116	282	35.23	1	281	4	270	3.0e-43	168	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
650743117	391	19.7	36	370	43	374	2.0e-08	54.1	COG2814	Predicted arabinose efflux permease, MFS family	394
650743118	249	21.15	46	244	2	208	2.0e-05	43.4	COG2755	Lysophospholipase L1 or related esterase	216
650743119	613	33.24	244	613	3	372	1.0e-61	231	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650743120	338	34.04	1	332	2	325	3.0e-71	262	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650743121	334	47.04	32	334	11	312	3.0e-97	348	COG3958	Transketolase, C-terminal subunit	312
650743122	298	45.61	22	260	6	243	1.0e-83	303	COG3959	Transketolase, N-terminal subunit	243
650743123	249	39.92	1	247	1	251	1.0e-42	166	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650743124	321	26.33	25	317	1	295	2.0e-28	119	COG0583	DNA-binding transcriptional regulator, LysR family	297
650743125	231	40.71	11	231	2	226	3.0e-50	192	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650743126	867	43.52	6	867	2	880	0.0e+00	759	COG2205	K+-sensing histidine kinase KdpD	890
650743129	199	46.97	1	195	1	189	4.0e-50	190	COG2156	K+-transporting ATPase, c chain	190
650743130	678	65.04	4	671	1	675	0.0e+00	959	COG2216	High-affinity K+ transport system, ATPase chain B	681
650743131	565	57.93	3	559	2	560	0.0e+00	624	COG2060	K+-transporting ATPase, A chain	560
650743133	519	34.41	12	517	4	521	0.0e+00	465	COG1384	Lysyl-tRNA synthetase, class I	521
650743137	301	34.01	7	283	2	292	5.0e-48	185	COG4974	Site-specific recombinase XerD	300
650743139	526	56.81	22	521	12	525	0.0e+00	748	COG4108	Peptide chain release factor RF-3	528
650743140	364	27.64	6	315	3	316	4.0e-48	185	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
650743141	161	37.4	36	158	2	123	3.0e-25	108	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
650743148	309	30.87	4	297	3	295	1.0e-47	183	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
650743152	345	27.27	21	327	15	302	6.0e-27	115	COG0524	Sugar or nucleoside kinase, ribokinase family	311
650743153	255	63.9	9	249	1	240	1.0e-109	389	COG1126	ABC-type polar amino acid transport system, ATPase component	240
650743154	274	45.62	52	267	5	215	5.0e-43	167	COG0765	ABC-type amino acid transport system, permease component	222
650743155	279	31.44	17	272	4	265	9.0e-30	124	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650743156	225	51.87	7	193	22	206	1.0e-60	226	COG2360	Leu/Phe-tRNA-protein transferase	221
650743157	485	37.57	148	468	63	408	4.0e-48	186	COG0840	Methyl-accepting chemotaxis protein	408
650743159	171	48.08	46	149	11	114	1.0e-18	86	COG5349	Uncharacterized conserved protein, DUF983 family	126
650743160	465	33.33	18	454	2	453	1.0e-76	280	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
650743161	298	32.33	3	297	2	296	2.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
650743162	191	21.18	1	170	8	176	4.0e-05	41.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650743163	153	76.35	6	153	7	154	8.0e-65	239	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
650743164	107	32.5	9	88	4	83	4.0e-11	59.6	COG1359	Quinol monooxygenase YgiN	100
650743165	215	38.83	20	207	4	187	5.0e-30	124	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
650743166	265	37.4	16	262	6	257	6.0e-44	171	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650743167	517	36.8	4	496	13	523	3.0e-93	335	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650743168	172	54.61	12	163	4	155	6.0e-45	173	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
650743169	272	33.33	4	272	2	281	1.0e-36	146	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
650743170	919	34.34	1	730	66	731	2.0e-111	397	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
650743171	280	31.15	158	279	3	124	3.0e-15	75.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650743172	207	30.88	1	200	4	201	6.0e-41	160	COG0288	Carbonic anhydrase	207
650743173	270	54.23	12	270	1	260	8.0e-88	317	COG0413	Ketopantoate hydroxymethyltransferase	268
650743174	204	49.04	1	204	1	205	8.0e-52	196	COG0522	Ribosomal protein S4 or related protein	205
650743176	548	38.75	31	547	16	522	9.0e-112	397	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650743178	409	57.33	5	153	2	150	5.0e-52	198	COG1017	Hemoglobin-like flavoprotein	150
650743179	386	38.42	26	382	13	378	4.0e-76	278	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
650743180	639	31.48	5	613	1	589	1.0e-103	371	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
650743182	285	29.2	11	274	4	277	2.0e-30	126	COG1792	Cell shape-determining protein MreC	284
650743185	314	37.07	15	302	1	289	6.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
650743186	227	32.57	6	223	3	213	8.0e-37	147	COG2121	Uncharacterized conserved protein, lysophospholipid acyltransferase (LPLAT) superfamily	214
650743187	412	41.96	5	391	2	399	2.0e-96	346	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
650743188	315	39.32	1	309	3	323	2.0e-55	209	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
650743189	295	29.93	14	293	23	299	3.0e-50	192	COG1560	Lauroyl/myristoyl acyltransferase	308
650743190	469	25.45	8	445	7	446	8.0e-29	122	COG0531	Amino acid transporter	466
650743191	354	44.73	5	354	4	345	4.0e-117	414	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
650743193	256	36.33	6	254	5	259	2.0e-43	169	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
650743194	474	46.34	206	327	13	134	1.0e-26	114	COG3474	Cytochrome c2	135
650743195	247	47.56	8	247	4	244	1.0e-73	269	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
650743196	287	40.86	1	276	1	278	6.0e-76	277	COG0077	Prephenate dehydratase	279
650743199	199	52.43	13	195	1	184	8.0e-53	200	COG0164	Ribonuclease HII	199
650743200	164	46.53	22	163	5	148	1.0e-32	132	COG3260	Ni,Fe-hydrogenase III small subunit	148
650743204	294	33.33	26	213	2	190	5.0e-28	118	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
650743205	942	43.95	10	942	2	930	0.0e+00	1062	COG0060	Isoleucyl-tRNA synthetase	933
650743206	177	39.75	5	162	3	161	5.0e-30	123	COG0597	Lipoprotein signal peptidase	167
650743208	409	27.6	10	392	1	379	7.0e-17	82.2	COG2814	Predicted arabinose efflux permease, MFS family	394
650743209	302	40.67	33	292	43	308	2.0e-34	140	COG0657	Acetyl esterase/lipase	312
650743210	582	42.66	1	580	1	637	0.0e+00	551	COG0323	DNA mismatch repair ATPase MutL	638
650743212	255	41.44	1	251	1	251	2.0e-29	122	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650743213	573	33.9	26	546	1	524	5.0e-113	401	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
650743214	299	48.63	2	292	1	285	2.0e-72	265	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
650743215	365	25.08	4	325	2	257	6.0e-29	121	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650743216	391	45.64	13	391	3	391	1.0e-79	290	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650743217	304	50.87	10	294	2	287	1.0e-81	296	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
650743218	383	46.89	4	382	8	390	3.0e-115	408	COG0372	Citrate synthase	390
650743219	499	35.31	19	488	7	452	1.0e-99	357	COG2079	2-methylcitrate dehydratase PrpD	453
650743220	546	36.36	9	546	8	530	7.0e-109	388	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650743221	258	35.8	8	254	1	249	7.0e-37	147	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650743223	547	36.58	90	540	3	474	4.0e-64	239	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
650743225	356	54.02	7	353	2	337	0.0e+00	482	COG1088	dTDP-D-glucose 4,6-dehydratase	340
650743226	293	54.9	3	288	1	283	3.0e-102	364	COG1209	dTDP-glucose pyrophosphorylase	286
650743227	184	50.28	1	177	2	173	4.0e-55	207	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
650743228	301	44.95	5	291	2	277	8.0e-75	274	COG1091	dTDP-4-dehydrorhamnose reductase	281
650743230	583	38.51	8	573	23	594	0.0e+00	495	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
650743231	677	54.12	24	677	3	662	0.0e+00	886	COG0021	Transketolase	663
650743232	337	59.76	2	336	1	332	5.0e-123	434	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
650743233	397	47.63	1	397	1	393	5.0e-130	458	COG0126	3-phosphoglycerate kinase	395
650743234	483	39.51	39	481	17	454	2.0e-106	379	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
650743235	358	29.36	10	351	4	322	1.0e-25	111	COG1612	Heme A synthase	323
650743236	367	30.84	24	367	1	319	3.0e-34	139	COG1612	Heme A synthase	323
650743237	424	71.7	1	424	4	420	0.0e+00	696	COG1158	Transcription termination factor Rho	422
650743238	207	30.05	8	207	6	208	8.0e-18	83.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
650743239	435	60.38	7	427	2	420	0.0e+00	645	COG0499	S-adenosylhomocysteine hydrolase	420
650743241	401	44.61	1	397	6	402	3.0e-97	348	COG0303	Molybdopterin biosynthesis enzyme	404
650743242	158	67.72	1	158	1	157	6.0e-56	210	COG0315	Molybdenum cofactor biosynthesis enzyme	157
650743243	270	54.65	10	267	1	254	3.0e-83	301	COG0134	Indole-3-glycerol phosphate synthase	254
650743244	544	52.11	201	530	3	334	2.0e-100	360	COG0547	Anthranilate phosphoribosyltransferase	338
650743245	504	48.19	28	494	7	459	0.0e+00	469	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
650743247	253	44.14	1	252	2	249	7.0e-67	247	COG0149	Triosephosphate isomerase	251
650743248	160	48.72	1	78	1	78	2.0e-17	81.8	COG1314	Preprotein translocase subunit SecG	86
650743249	543	63.1	2	541	1	531	0.0e+00	849	COG0504	CTP synthase (UTP-ammonia lyase)	533
650743250	275	62.13	3	274	2	273	1.0e-121	429	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
650743253	257	32.09	1	254	2	266	6.0e-47	181	COG1018	Ferredoxin-NADP reductase	266
650743254	722	45.45	253	721	104	544	0.0e+00	479	COG2225	Malate synthase	545
650743255	690	29.76	342	591	6	253	8.0e-39	155	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
650743259	560	22.14	19	560	10	554	4.0e-53	202	COG2831	Hemolysin activation/secretion protein	554
650743261	188	23.24	1	172	1	181	4.0e-11	61.1	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
650743262	446	25.56	16	446	10	440	1.0e-54	207	COG2067	Long-chain fatty acid transport protein	440
650743263	541	45.66	1	533	3	537	2.0e-130	459	COG2303	Choline dehydrogenase or related flavoprotein	542
650743264	471	37.47	4	448	27	472	6.0e-91	328	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650743265	179	22.22	44	169	23	136	2.0e-04	39.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
650743266	572	41.18	35	569	11	524	1.0e-127	450	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650743267	428	33.72	8	428	2	391	5.0e-56	212	COG0183	Acetyl-CoA acetyltransferase	392
650743269	467	39.27	228	461	5	248	3.0e-33	136	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650743270	858	29.02	140	514	22	382	4.0e-43	170	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650743271	356	28.44	120	335	12	216	3.0e-36	146	COG0543	NAD(P)H-flavin reductase	252
650743276	384	45.89	1	377	1	371	4.0e-99	355	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
650743277	235	38.71	2	217	3	218	5.0e-29	121	COG1802	DNA-binding transcriptional regulator, GntR family	230
650743278	455	27.21	13	453	5	451	1.0e-59	224	COG2079	2-methylcitrate dehydratase PrpD	453
650743279	466	16.63	49	459	37	437	7.0e-05	42.5	COG2271	Sugar phosphate permease	448
650743280	353	43.58	1	353	4	348	9.0e-95	340	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
650743281	594	30.88	4	588	15	606	8.0e-99	355	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
650743282	424	46.67	4	224	2	223	4.0e-58	219	COG0120	Ribose 5-phosphate isomerase	227
650743283	245	34.57	7	240	2	233	5.0e-44	171	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
650743284	272	30.19	7	269	5	263	3.0e-43	169	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
650743285	534	49.41	22	523	3	481	0.0e+00	577	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
650743286	334	54.49	1	323	1	297	6.0e-108	384	COG1023	6-phosphogluconate dehydrogenase (decarboxylating)	300
650743287	943	29.86	441	764	69	428	4.0e-39	157	COG0166	Glucose-6-phosphate isomerase	446
650743288	601	70.22	1	600	1	601	0.0e+00	1061	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
650743289	451	28.34	16	451	9	426	1.0e-48	187	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
650743295	346	31.21	4	329	1	303	4.0e-28	118	COG3547	Transposase	303
650743296	180	37.14	38	176	3	138	2.0e-16	78.9	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
650743297	315	33.55	5	300	1	295	6.0e-35	141	COG0583	DNA-binding transcriptional regulator, LysR family	297
650743301	346	31.21	4	329	1	303	4.0e-28	118	COG3547	Transposase	303
650743302	577	17.04	67	479	10	432	5.0e-26	112	COG5421	Transposase	480
650743303	426	36.11	85	383	85	408	4.0e-43	169	COG0840	Methyl-accepting chemotaxis protein	408
650743308	642	28.08	216	606	15	417	2.0e-43	171	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
650743310	279	22.18	7	279	109	379	5.0e-13	68.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650743311	408	15	12	247	1	235	5.0e-05	42.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
650743313	594	38.77	65	562	6	485	7.0e-90	325	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
650743314	328	57.32	11	324	2	327	2.0e-114	405	COG1494	Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase or related protein	332
650743315	429	48.62	5	322	4	330	5.0e-93	335	COG0460	Homoserine dehydrogenase	333
650743316	403	43.33	9	390	5	390	2.0e-104	372	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
650743318	599	53.23	148	596	7	445	0.0e+00	551	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
650743321	320	47.06	5	320	1	323	1.0e-91	329	COG0523	GTPase, G3E family	323
650743323	274	44.96	1	274	3	278	2.0e-83	302	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
650743324	610	59.77	4	607	3	603	0.0e+00	913	COG1217	Predicted membrane GTPase involved in stress response	603
650743327	622	43.15	1	519	1	529	0.0e+00	491	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
650743328	172	53.73	34	167	1	134	5.0e-53	200	COG0105	Nucleoside diphosphate kinase	135
650743330	346	66.47	5	343	1	340	3.0e-126	445	COG1077	Actin-like ATPase involved in cell morphogenesis	342
650743331	292	23.74	154	292	17	151	2.0e-05	43.4	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
650743332	149	37.27	34	142	15	124	2.0e-12	65.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
650743333	235	34.58	1	231	1	239	3.0e-43	168	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
650743334	508	43.77	26	384	4	340	6.0e-70	258	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
650743335	308	33.44	3	308	7	261	2.0e-53	202	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
650743336	621	61.18	8	431	2	426	0.0e+00	627	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
650743337	369	59	2	358	1	358	0.0e+00	511	COG0082	Chorismate synthase	369
650743339	418	28.11	35	364	10	337	1.0e-31	131	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650743340	145	40.43	2	142	4	141	5.0e-22	96.9	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
650743341	469	41.21	1	361	1	339	2.0e-60	226	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
650743343	222	28.27	14	204	14	195	1.0e-23	103	COG0400	Predicted esterase	207
650743344	186	36.24	22	168	1	146	3.0e-24	105	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
650743345	404	71.9	11	404	1	394	0.0e+00	708	COG0133	Tryptophan synthase beta chain	396
650743346	276	49.26	1	270	1	264	1.0e-75	276	COG0159	Tryptophan synthase alpha chain	265
650743347	421	55.56	1	421	1	423	0.0e+00	522	COG0151	Phosphoribosylamine-glycine ligase	428
650743348	462	42.09	10	455	1	440	5.0e-115	408	COG1570	Exonuclease VII, large subunit	440
650743349	234	30.6	2	226	7	237	5.0e-26	111	COG5343	Anti-sigma-K factor RskA	240
650743350	165	36.21	1	165	5	177	2.0e-24	105	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650743352	150	35.61	1	132	4	135	8.0e-28	116	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
650743353	270	38.1	17	265	34	283	1.0e-43	170	COG3176	Putative hemolysin	292
650743354	169	45.22	11	164	3	157	2.0e-34	138	COG3814	Uncharacterized protein	157
650743355	548	37.94	44	353	2	297	7.0e-79	288	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
650743356	131	23.57	7	125	2	136	2.0e-08	51.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650743357	345	51.29	1	344	1	344	7.0e-116	410	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
650743358	376	54.22	6	372	1	367	0.0e+00	496	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
650743359	154	50.78	21	147	22	149	9.0e-47	179	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
650743360	353	51.47	6	341	2	337	2.0e-94	339	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
650743361	152	52.52	13	149	4	130	2.0e-36	145	COG1970	Large-conductance mechanosensitive channel	130
650743363	231	40.19	15	228	14	227	9.0e-35	140	COG1346	Putative effector of murein hydrolase	230
650743364	145	38.39	16	127	5	115	2.0e-13	68.2	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
650743365	309	39.02	3	302	2	297	2.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
650743366	460	52.03	2	420	1	413	0.0e+00	510	COG1004	UDP-glucose 6-dehydrogenase	414
650743367	581	22.67	41	193	54	224	2.0e-10	61.4	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
650743368	1046	25.26	77	253	25	208	4.0e-11	64.5	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
650743370	270	24.3	19	262	8	255	9.0e-22	97.3	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
650743371	450	46.38	6	443	1	435	0.0e+00	513	COG0621	tRNA A37 methylthiotransferase MiaB	437
650743372	333	50	11	333	13	342	2.0e-94	339	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
650743373	150	31.78	31	145	21	149	5.0e-21	93.8	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
650743377	103	50	1	95	1	96	2.0e-22	97.3	COG5470	Uncharacterized conserved protein, DUF1330 family	96
650743380	622	35.21	46	613	1	564	7.0e-108	385	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
650743381	349	24.93	6	341	2	381	2.0e-27	116	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650743383	349	38.69	40	344	29	324	1.0e-51	197	COG4158	Predicted ABC-type sugar transport system, permease component	329
650743384	329	33.1	6	293	4	293	1.0e-41	163	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650743385	503	41.36	1	191	4	187	4.0e-41	162	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
650743386	185	45.56	5	172	1	168	9.0e-43	166	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
650743387	400	40.47	22	399	11	383	9.0e-94	337	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
650743390	120	24.37	19	120	25	143	3.0e-05	40.7	COG3296	Uncharacterized conserved protein, Tic20 family	143
650743391	131	26.92	14	117	6	102	1.0e-10	59.2	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
650743393	686	36.41	54	683	16	606	9.0e-104	371	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
650743394	544	35.53	1	528	2	521	8.0e-87	314	COG0459	Chaperonin GroEL (HSP60 family)	524
650743395	340	27.24	32	322	1	291	5.0e-33	135	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
650743398	363	31.34	117	332	9	207	1.0e-36	147	COG0543	NAD(P)H-flavin reductase	252
650743404	87	42.68	1	82	1	78	1.0e-12	65	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
650743405	131	23.97	5	125	11	124	7.0e-07	46.4	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
650743408	435	25	1	402	3	387	5.0e-30	125	COG1252	NADH dehydrogenase, FAD-containing subunit	405
650743409	167	34.95	50	151	1	103	2.0e-09	55.6	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650743410	120	37.61	5	110	2	110	8.0e-14	69.2	COG0607	Rhodanese-related sulfurtransferase	110
650743411	336	25.66	6	334	19	352	1.0e-13	70.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
650743412	1089	25.94	8	1083	1	1008	0.0e+00	537	COG0841	Multidrug efflux pump subunit AcrB	1009
650743414	671	37.25	1	489	1	477	3.0e-59	223	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
650743415	318	37.58	1	313	1	308	6.0e-43	168	COG0650	Formate hydrogenlyase subunit 4	309
650743416	229	26.89	17	226	7	218	2.0e-14	73	COG4237	Hydrogenase-4 membrane subunit HyfE	218
650743417	482	34.22	60	431	70	428	1.0e-39	158	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
650743418	477	38.19	117	477	4	367	1.0e-80	294	COG3261	Ni,Fe-hydrogenase III large subunit	382
650743419	167	52.67	37	167	2	132	8.0e-43	166	COG3260	Ni,Fe-hydrogenase III small subunit	148
650743420	186	24.83	37	180	2	140	2.0e-14	72.6	COG2193	Bacterioferritin (cytochrome b1)	157
650743421	257	41.91	17	257	5	240	3.0e-53	201	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
650743422	449	54.43	3	448	1	463	0.0e+00	614	COG0215	Cysteinyl-tRNA synthetase	464
650743423	397	29.44	2	388	20	406	3.0e-41	163	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
650743424	427	27.44	9	424	2	409	3.0e-45	176	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
650743425	473	37	1	459	1	465	2.0e-72	266	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
650743426	114	27.52	7	112	15	115	3.0e-08	50.3	COG3462	Uncharacterized membrane protein	117
650743427	439	61.57	6	439	3	444	0.0e+00	619	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
650743428	183	67.82	10	183	2	175	1.0e-75	275	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
650743429	145	23.85	9	137	6	133	1.0e-05	42.5	COG3431	Uncharacterized membrane protein, DUF373 family	142
650743430	465	20.98	72	451	47	384	4.0e-07	49.8	COG2814	Predicted arabinose efflux permease, MFS family	394
650743431	196	62.76	1	196	2	195	4.0e-75	274	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
650743432	211	47.87	1	211	2	204	4.0e-70	257	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
650743433	186	28.46	51	172	34	153	7.0e-08	50.7	COG1247	L-amino acid N-acyltransferase YncA	169
650743434	246	47.92	2	241	1	236	9.0e-75	273	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
650743435	254	65.49	1	250	1	255	5.0e-104	370	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
650743436	164	46.07	53	141	1	89	2.0e-21	95.2	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
650743437	127	35.96	13	124	1	110	4.0e-23	100	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
650743438	683	41.73	1	375	2	375	1.0e-80	294	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
650743439	432	35.54	22	429	8	377	2.0e-80	293	COG1454	Alcohol dehydrogenase, class IV	377
650743440	262	20.7	25	248	17	212	6.0e-13	68	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650743441	253	37.89	3	248	1	251	1.0e-32	133	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650743442	340	40.27	42	336	10	299	6.0e-56	211	COG2421	Acetamidase/formamidase	305
650743443	258	36.68	3	251	1	248	4.0e-29	121	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650743444	236	30.25	9	231	6	241	2.0e-25	109	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
650743445	544	35.85	1	533	2	527	1.0e-107	384	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650743446	1586	41.45	15	1584	1	1588	0.0e+00	1261	COG2902	NAD-specific glutamate dehydrogenase	1592
650743447	633	52.01	11	602	2	587	0.0e+00	619	COG0465	ATP-dependent Zn proteases	596
650743448	204	18.47	1	197	10	255	7.0e-04	37.3	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
650743449	467	34.16	43	467	1	438	3.0e-58	219	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
650743450	283	20.24	39	258	37	286	1.0e-13	70.3	COG0657	Acetyl esterase/lipase	312
650743451	344	39.56	30	343	7	321	6.0e-70	258	COG0142	Geranylgeranyl pyrophosphate synthase	322
650743453	239	26.16	2	233	7	243	7.0e-36	144	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
650743454	155	24.24	8	138	11	132	8.0e-03	33.4	COG5622	Protein required for attachment to host cells	139
650743455	519	53.95	1	497	1	501	0.0e+00	556	COG0427	Acyl-CoA hydrolase	501
650743456	374	38.13	1	374	1	364	7.0e-78	284	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
650743457	577	40.23	55	574	2	521	5.0e-126	445	COG4986	ABC-type anion transport system, duplicated permease component	523
650743458	439	46.85	10	263	3	248	6.0e-84	304	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
650743459	482	61.26	18	478	1	462	0.0e+00	647	COG0114	Fumarate hydratase class II	462
650743460	322	31.33	1	290	1	296	4.0e-24	105	COG0583	DNA-binding transcriptional regulator, LysR family	297
650743461	141	32.33	1	131	3	133	2.0e-06	45	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
650743462	260	46.86	1	234	8	243	4.0e-58	218	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
650743463	397	25.07	18	378	31	382	8.0e-15	75.2	COG2814	Predicted arabinose efflux permease, MFS family	394
650743464	509	23.12	1	499	2	491	2.0e-36	147	COG0591	Na+/proline symporter	493
650743465	185	47.78	1	179	8	185	4.0e-58	217	COG0194	Guanylate kinase	191
650743466	302	43.33	5	302	2	290	1.0e-68	253	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
650743467	358	31.36	9	288	16	299	1.0e-54	207	COG0863	DNA modification methylase	302
650743468	256	46.9	1	255	2	257	5.0e-60	224	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650743469	339	30.72	8	323	5	304	3.0e-46	179	COG0492	Thioredoxin reductase	305
650743470	149	38.93	4	149	1	147	4.0e-28	117	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
650743471	959	34.99	8	683	6	697	6.0e-73	269	COG3893	Inactivated superfamily I helicase	697
650743472	1157	28.61	9	1141	6	1139	0.0e+00	532	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
650743474	134	43.31	5	131	4	130	1.0e-36	145	COG1607	Acyl-CoA hydrolase	157
650743475	474	23.54	19	460	6	391	9.0e-14	71.8	COG2814	Predicted arabinose efflux permease, MFS family	394
650743476	350	47.69	1	322	1	311	2.0e-82	299	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650743477	223	26.74	16	201	22	208	1.0e-21	96.6	COG0811	Biopolymer transport protein ExbB/TolQ	216
650743478	154	24.44	2	134	5	137	6.0e-16	76.8	COG0848	Biopolymer transport protein ExbD	137
650743479	457	41.96	10	455	3	456	1.0e-82	301	COG0277	FAD/FMN-containing dehydrogenase	459
650743480	275	45.56	6	273	1	266	1.0e-82	300	COG1692	Calcineurin-like phosphoesterase	266
650743481	179	33.71	1	177	4	181	1.0e-25	109	COG3038	Cytochrome b561	181
650743483	223	47.17	1	212	1	208	2.0e-53	202	COG2808	Predicted FMN-binding regulatory protein PaiB	209
650743484	552	49.04	188	549	2	357	7.0e-112	398	COG0337	3-dehydroquinate synthetase	360
650743485	320	47.52	15	310	1	300	5.0e-81	294	COG4974	Site-specific recombinase XerD	300
650743486	281	29.76	32	281	1	241	7.0e-30	124	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
650743488	691	47.06	19	691	18	693	0.0e+00	716	COG1298	Flagellar biosynthesis pathway, component FlhA	696
650743489	451	43.53	1	445	5	464	6.0e-112	397	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
650743491	336	38.41	8	332	10	337	4.0e-66	245	COG1536	Flagellar motor switch protein FliG	339
650743492	520	28.97	1	517	9	545	4.0e-82	299	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
650743493	154	51.08	4	142	12	150	4.0e-40	157	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
650743494	237	47.5	3	237	2	239	1.0e-61	229	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
650743495	247	38.33	9	240	1	240	9.0e-57	213	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
650743496	133	43.26	2	133	47	187	1.0e-29	121	COG0742	16S rRNA G966 N2-methylase RsmD	187
650743498	452	30.17	11	418	21	422	1.0e-74	274	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
650743499	615	36.49	31	614	11	593	0.0e+00	503	COG1164	Oligoendopeptidase F	598
650743500	273	45.69	1	259	1	267	8.0e-82	297	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
650743501	321	47.08	8	320	5	329	1.0e-76	279	COG0240	Glycerol-3-phosphate dehydrogenase	329
650743502	235	23.41	1	202	1	201	4.0e-16	78.4	COG1011	FMN phosphatase YigB, HAD superfamily	229
650743504	796	30.7	476	787	10	316	1.0e-31	132	COG0668	Small-conductance mechanosensitive channel	316
650743505	241	44.74	14	240	1	219	1.0e-47	183	COG4340	Uncharacterized protein	226
650743506	335	51.44	9	316	1	300	1.0e-96	346	COG0031	Cysteine synthase	300
650743507	136	25.2	10	136	11	109	1.0e-10	58.8	COG0607	Rhodanese-related sulfurtransferase	110
650743508	409	24.54	26	407	16	394	5.0e-18	86	COG2814	Predicted arabinose efflux permease, MFS family	394
650743509	264	50.2	11	258	1	251	4.0e-93	334	COG0024	Methionine aminopeptidase	255
650743510	255	39.63	39	255	8	224	2.0e-57	215	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
650743512	241	41.85	9	235	5	223	4.0e-41	161	COG1040	Predicted amidophosphoribosyltransferases	225
650743513	92	50	9	87	1	80	4.0e-22	96.2	COG0695	Glutaredoxin	80
650743514	151	46	1	150	1	140	2.0e-34	138	COG5319	Uncharacterized protein	142
650743515	180	46.02	5	180	1	174	1.0e-47	182	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
650743517	469	51.82	136	461	3	332	3.0e-105	375	COG3800	Predicted transcriptional regulator	332
650743518	461	70.26	23	431	19	433	0.0e+00	614	COG2224	Isocitrate lyase	433
650743519	358	42.56	17	347	10	339	1.0e-89	323	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
650743520	150	27.74	12	145	25	179	1.0e-11	62.7	COG5389	Uncharacterized protein	181
650743521	892	52.33	295	892	1	593	0.0e+00	711	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
650743522	75	42.55	22	67	16	62	8.0e-09	51.9	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
650743525	184	35.29	3	184	2	181	2.0e-51	195	COG0717	Deoxycytidine triphosphate deaminase	183
650743526	418	62.62	1	418	1	420	0.0e+00	582	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
650743527	424	49.82	106	385	4	283	9.0e-93	334	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
650743528	186	44.22	4	150	1	147	1.0e-36	146	COG0359	Ribosomal protein L9	148
650743529	95	68.57	21	90	6	75	4.0e-21	93	COG0238	Ribosomal protein S18	75
650743530	158	40.91	4	113	3	112	9.0e-24	102	COG0360	Ribosomal protein S6	112
650743531	99	27.66	1	94	3	96	2.0e-16	77.3	COG1359	Quinol monooxygenase YgiN	100
650743532	662	55.24	1	658	1	644	0.0e+00	752	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
650743533	262	40.24	11	259	12	257	3.0e-36	145	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650743534	535	46.27	12	535	1	526	0.0e+00	617	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
650743535	307	29.27	9	246	13	251	7.0e-26	111	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
650743537	310	19.48	9	301	3	300	4.0e-15	75.9	COG1216	Glycosyltransferase, GT2 family	305
650743538	331	23.3	1	322	2	323	6.0e-13	68.8	COG3594	Fucose 4-O-acetylase or related acetyltransferase	343
650743541	718	29.6	19	457	13	458	4.0e-42	166	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
650743542	196	34.72	12	196	11	201	9.0e-23	100	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
650743543	319	49.37	1	316	1	309	9.0e-88	317	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
650743544	249	49.21	6	247	1	251	5.0e-42	164	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650743545	79	58.97	1	78	3	80	6.0e-13	65.7	COG0236	Acyl carrier protein	80
650743546	422	58.06	2	421	1	411	0.0e+00	475	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
650743547	331	37.09	1	319	7	339	1.0e-76	280	COG1559	Cell division protein YceG, involved in septum cleavage	342
650743548	322	26.22	161	317	22	181	2.0e-08	53.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
650743549	279	45.77	3	279	1	270	2.0e-72	266	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
650743550	371	34.85	1	368	10	405	8.0e-65	241	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
650743552	276	45.59	2	272	9	275	5.0e-78	284	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
650743555	295	33.45	6	291	13	297	1.0e-51	197	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
650743556	185	48.65	1	184	1	182	4.0e-47	181	COG2096	Cob(I)alamin adenosyltransferase	184
650743558	257	44.23	4	257	3	262	1.0e-60	226	COG0300	Short-chain dehydrogenase	265
650743559	298	57.33	2	297	15	321	4.0e-91	328	COG4111	Uncharacterized conserved protein	322
650743560	326	47.15	15	325	11	322	2.0e-102	365	COG0379	Quinolinate synthase	324
650743561	493	49.09	12	472	11	506	2.0e-128	452	COG0029	Aspartate oxidase	518
650743562	281	60.07	4	279	1	277	8.0e-96	343	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
650743565	258	35.08	12	248	3	250	1.0e-52	200	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
650743566	334	27.12	19	189	11	186	4.0e-18	85.8	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650743567	432	49.15	24	432	5	417	0.0e+00	486	COG0014	Gamma-glutamyl phosphate reductase	417
650743568	165	28.48	1	155	38	175	3.0e-20	91.5	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
650743569	107	44.12	1	102	6	107	3.0e-25	106	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
650743570	151	42.76	2	147	4	155	1.0e-34	138	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
650743573	328	53.85	120	300	1	181	4.0e-43	168	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
650743576	386	47.3	5	383	6	387	1.0e-82	300	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650743577	219	38.29	1	219	8	229	2.0e-24	105	COG1802	DNA-binding transcriptional regulator, GntR family	230
650743579	447	38.95	1	441	2	434	1.0e-101	363	COG4091	Predicted homoserine dehydrogenase, contains C-terminal SAF domain	438
650743580	444	36.11	8	436	1	415	9.0e-112	397	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
650743581	767	39.66	16	764	14	731	4.0e-119	422	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
650743582	171	28.48	1	165	1	163	4.0e-26	111	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
650743584	217	26.7	30	217	1	187	2.0e-14	72.8	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
650743585	231	29.02	1	217	2	220	6.0e-17	81	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650743587	568	26.55	37	567	117	773	2.0e-70	260	COG4993	Glucose dehydrogenase	773
650743591	291	42.62	7	248	4	247	3.0e-59	222	COG1484	DNA replication protein DnaC	254
650743594	599	32.39	39	457	11	388	2.0e-58	220	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650743595	435	26.88	1	186	6	177	9.0e-07	48.5	COG3226	DNA-binding transcriptional regulator YbjK	204
650743596	263	38.61	8	253	1	251	4.0e-35	141	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650743597	390	37.56	1	390	1	392	6.0e-74	271	COG0183	Acetyl-CoA acetyltransferase	392
650743598	154	34.19	1	154	8	159	3.0e-26	110	COG2030	Acyl dehydratase	159
650743599	326	46.32	1	324	1	315	8.0e-90	323	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650743600	498	20.95	18	480	1	497	8.0e-20	92.3	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
650743601	240	25.47	19	224	1	212	8.0e-21	94.1	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
650743602	1244	69.8	1	1231	1	1227	0.0e+00	2020	COG5013	Nitrate reductase alpha subunit	1227
650743603	508	73.55	1	497	1	499	0.0e+00	882	COG1140	Nitrate reductase beta subunit	513
650743604	218	47.16	1	176	4	175	1.0e-35	143	COG2180	Nitrate reductase assembly protein NarJ, required for insertion of molybdenum cofactor	179
650743605	238	45.61	5	230	2	228	9.0e-53	200	COG2181	Nitrate reductase gamma subunit	228
650743607	448	29.85	22	426	15	397	6.0e-43	168	COG2223	Nitrate/nitrite transporter NarK	417
650743609	555	36.73	240	538	85	408	2.0e-41	164	COG0840	Methyl-accepting chemotaxis protein	408
650743610	348	36.76	9	345	1	333	1.0e-67	250	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650743611	342	39.6	1	342	2	350	4.0e-68	251	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
650743612	265	40.94	17	262	1	251	2.0e-39	156	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650743613	294	44.76	2	286	1	285	3.0e-54	205	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
650743614	505	46.39	1	488	4	500	0.0e+00	482	COG1129	ABC-type sugar transport system, ATPase component	500
650743615	354	37.7	25	336	4	313	8.0e-43	168	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650743616	368	22.91	25	342	2	314	4.0e-16	79.4	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650743618	452	22.66	1	452	7	439	3.0e-23	103	COG3659	Carbohydrate-selective porin OprB	439
650743619	456	20.19	19	430	12	384	4.0e-07	49.8	COG2814	Predicted arabinose efflux permease, MFS family	394
650743620	274	29.08	12	251	3	243	2.0e-23	103	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
650743622	345	30.82	6	321	3	317	3.0e-38	152	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650743623	349	46.06	33	347	5	316	6.0e-53	201	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650743625	370	45.61	194	356	1	171	4.0e-32	132	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
650743626	331	47.73	3	331	1	322	7.0e-105	373	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
650743627	195	58.97	2	193	1	193	4.0e-62	230	COG3820	Uncharacterized protein	230
650743628	67	43.75	4	67	5	67	6.0e-06	42.7	COG5481	Uncharacterized protein	67
650743629	164	62.73	1	161	1	159	4.0e-57	213	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
650743630	381	52.86	9	356	1	350	3.0e-122	431	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
650743631	522	32.49	58	517	1	440	1.0e-72	268	COG1793	ATP-dependent DNA ligase	444
650743632	354	24.26	24	352	19	426	8.0e-44	171	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
650743633	824	31.61	18	823	7	807	0.0e+00	677	COG1201	Lhr-like helicase	814
650743634	225	35.56	13	217	3	225	2.0e-31	129	COG1407	Metallophosphoesterase superfamily enzyme	235
650743635	471	45.15	1	466	1	460	3.0e-130	459	COG0415	Deoxyribodipyrimidine photolyase	461
650743636	426	49.28	5	416	10	424	2.0e-123	435	COG2907	Predicted NAD/FAD-binding protein	447
650743637	254	43.09	4	246	7	252	3.0e-54	205	COG3496	Uncharacterized conserved protein, DUF1365 family	261
650743638	405	47.39	118	404	3	283	5.0e-88	318	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
650743639	436	24.83	4	435	12	453	2.0e-50	193	COG2211	Na+/melibiose symporter or related transporter	467
650743641	463	54.49	1	453	1	454	0.0e+00	526	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
650743642	410	50.61	1	409	1	404	1.0e-113	403	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
650743643	949	54.21	13	949	12	906	0.0e+00	1229	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
650743644	291	64.48	1	290	1	290	5.0e-115	407	COG0074	Succinyl-CoA synthetase, alpha subunit	293
650743645	398	60.4	1	397	1	387	0.0e+00	515	COG0045	Succinyl-CoA synthetase, beta subunit	387
650743646	384	44.74	13	383	11	367	7.0e-104	370	COG1485	Predicted ATPase	367
650743648	389	35.31	9	384	4	387	2.0e-79	289	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
650743650	317	35.75	98	301	3	209	2.0e-32	133	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
650743653	379	38.79	1	375	1	346	2.0e-65	243	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
650743655	584	42.39	1	577	1	572	1.0e-117	416	COG4987	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components	573
650743656	589	46.96	30	585	1	557	0.0e+00	505	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
650743657	436	29.62	8	414	20	432	3.0e-45	176	COG0038	H+/Cl- antiporter ClcA	443
650743658	167	22.73	33	163	7	130	8.0e-08	50.4	COG1765	Uncharacterized OsmC-related protein	137
650743659	325	36.09	60	320	4	250	5.0e-39	155	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
650743660	260	35	3	253	1	249	9.0e-28	117	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650743661	405	47.87	7	399	5	396	1.0e-106	380	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650743662	286	20.07	12	280	2	239	3.0e-07	49.8	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
650743664	383	57.55	1	382	1	371	0.0e+00	472	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
650743665	635	63.06	1	600	4	579	0.0e+00	697	COG0443	Molecular chaperone DnaK (HSP70)	579
650743666	202	36.13	2	192	7	192	9.0e-32	130	COG0576	Molecular chaperone GrpE (heat shock protein)	193
650743668	254	36.48	9	239	8	249	5.0e-22	98.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650743671	319	37.42	1	318	5	327	2.0e-64	239	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
650743672	160	54.23	9	147	4	145	1.0e-39	155	COG0328	Ribonuclease HI	154
650743673	247	42.75	7	245	1	251	1.0e-34	140	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650743674	361	51.42	1	351	1	338	6.0e-115	407	COG3839	ABC-type sugar transport system, ATPase component	338
650743675	273	40.07	1	273	5	281	6.0e-49	187	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650743676	332	36.52	45	325	8	287	5.0e-53	202	COG1175	ABC-type sugar transport system, permease component	295
650743677	449	27.15	13	432	5	427	7.0e-37	148	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650743678	339	32.19	1	337	2	350	1.0e-57	217	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
650743679	496	35.35	1	489	3	496	9.0e-88	317	COG1070	Sugar (pentulose or hexulose) kinase	502
650743680	345	40.06	7	331	5	321	7.0e-68	251	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
650743681	146	37.84	3	146	15	159	1.0e-21	95.9	COG2030	Acyl dehydratase	159
650743682	367	47.21	28	367	4	341	2.0e-92	332	COG1420	Transcriptional regulator of heat shock response	346
650743683	243	54.77	1	240	4	229	3.0e-67	248	COG0689	Ribonuclease PH	230
650743684	201	45.26	12	198	1	189	8.0e-49	186	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
650743685	1514	57.38	719	1203	1	482	0.0e+00	625	COG0069	Glutamate synthase domain 2	485
650743686	483	44.47	23	474	1	457	4.0e-125	442	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
650743687	316	33.85	9	265	5	250	3.0e-21	96.1	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
650743690	340	55	25	222	2	201	2.0e-59	223	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
650743691	246	22.33	22	234	6	215	2.0e-14	73.1	COG5375	Uncharacterized protein	216
650743692	323	23.57	175	312	46	173	1.0e-06	47.2	COG1934	Lipopolysaccharide export system protein LptA	173
650743693	264	65.27	28	264	5	243	4.0e-104	371	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
650743694	217	40.22	6	97	3	93	2.0e-16	79.5	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
650743695	192	49.19	1	184	2	186	2.0e-64	238	COG0193	Peptidyl-tRNA hydrolase	190
650743696	364	58.71	1	364	1	372	0.0e+00	481	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
650743697	717	45.58	1	716	1	730	0.0e+00	691	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
650743698	197	33.71	17	194	2	178	3.0e-34	138	COG0712	FoF1-type ATP synthase, delta subunit	178
650743699	510	69.02	1	510	1	501	0.0e+00	819	COG0056	FoF1-type ATP synthase, alpha subunit	504
650743700	296	44.86	5	296	1	286	9.0e-83	300	COG0224	FoF1-type ATP synthase, gamma subunit	287
650743701	476	75.79	6	475	3	468	0.0e+00	817	COG0055	FoF1-type ATP synthase, beta subunit	468
650743702	137	36.04	5	114	6	116	1.0e-19	89.2	COG0355	FoF1-type ATP synthase, epsilon subunit	135
650743704	434	19.31	85	427	65	392	1.0e-09	58.3	COG2814	Predicted arabinose efflux permease, MFS family	394
650743705	649	32.54	103	639	1	515	1.0e-67	251	COG1657	Squalene cyclase	517
650743707	323	62.76	73	311	1	239	2.0e-97	349	COG1186	Protein chain release factor B	239
650743708	830	40.61	2	770	4	764	0.0e+00	702	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
650743711	268	47.12	7	265	1	277	5.0e-45	174	COG2301	Citrate lyase beta subunit	283
650743712	334	36.25	6	332	5	332	3.0e-76	278	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
650743713	612	34.93	236	610	1	375	1.0e-69	258	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
650743714	249	42.13	1	240	1	251	9.0e-39	153	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650743715	382	45.69	3	381	34	410	6.0e-104	371	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
650743716	256	56.35	3	254	1	252	8.0e-100	356	COG0052	Ribosomal protein S2	252
650743717	301	52.63	1	301	1	296	3.0e-88	318	COG0264	Translation elongation factor EF-Ts	296
650743719	550	36.11	206	504	85	408	4.0e-44	173	COG0840	Methyl-accepting chemotaxis protein	408
650743720	130	41.73	1	126	2	127	2.0e-21	94.7	COG3791	Uncharacterized conserved protein	133
650743722	1171	40.85	325	1171	3	842	0.0e+00	819	COG1410	Methionine synthase I, cobalamin-binding domain	842
650743723	330	24.07	42	310	31	286	4.0e-09	55.7	COG5006	Threonine/homoserine efflux transporter RhtA	292
650743728	188	37.69	1	130	2	131	4.0e-31	127	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
650743729	275	43.02	5	265	1	258	2.0e-63	236	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
650743732	342	26.57	135	339	37	241	1.0e-27	117	COG1360	Flagellar motor protein MotB	244
650743733	622	55.68	8	604	19	620	0.0e+00	579	COG4547	Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib...	620
650743734	338	20.63	51	327	21	294	3.0e-37	149	COG0714	MoxR-like ATPase	329
650743736	97	38.14	1	97	1	87	1.0e-16	78.5	COG0271	Stress-induced morphogen (activity unknown)	90
650743738	264	41.18	1	254	3	256	5.0e-50	191	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650743739	315	50.64	1	306	2	307	2.0e-68	252	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
650743740	330	54.63	1	320	17	334	2.0e-106	378	COG0136	Aspartate-semialdehyde dehydrogenase	334
650743742	185	43.09	2	181	9	189	1.0e-34	139	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
650743743	212	37.5	5	212	3	203	7.0e-28	117	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
650743744	113	50	1	94	2	94	5.0e-27	112	COG0776	Bacterial nucleoid DNA-binding protein	94
650743746	234	50.44	9	234	12	235	4.0e-45	174	COG0284	Orotidine-5'-phosphate decarboxylase	240
650743747	205	35.1	1	202	1	205	9.0e-42	163	COG0135	Phosphoribosylanthranilate isomerase	208
650743748	275	47.31	1	275	1	273	4.0e-85	307	COG0266	Formamidopyrimidine-DNA glycosylase	273
650743749	249	48.12	13	249	1	238	3.0e-74	271	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
650743750	402	50	8	402	2	392	4.0e-103	368	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
650743751	154	58.5	1	147	1	146	7.0e-48	183	COG0756	dUTPase	148
650743752	265	30.28	11	250	9	259	1.0e-34	140	COG0300	Short-chain dehydrogenase	265
650743753	513	52.16	1	510	1	505	0.0e+00	640	COG3046	Uncharacterized protein related to deoxyribodipyrimidine photolyase	505
650743755	172	43.57	1	140	1	132	1.0e-26	112	COG2062	Phosphohistidine phosphatase SixA	163
650743756	439	56.05	35	438	1	390	0.0e+00	496	COG0372	Citrate synthase	390
650743757	115	30.97	1	113	3	103	6.0e-10	56.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650743758	355	43.63	1	350	3	359	3.0e-86	312	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
650743759	254	38.04	8	252	1	250	1.0e-34	139	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650743762	319	33.96	101	306	2	203	9.0e-28	117	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
650743765	570	27.54	9	570	109	754	3.0e-79	289	COG4993	Glucose dehydrogenase	773
650743766	129	65.22	5	119	2	116	5.0e-44	169	COG3564	Uncharacterized conserved protein, DUF779 family	116
650743767	510	44.67	23	505	1	472	0.0e+00	487	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650743768	652	36.53	1	641	1	599	2.0e-125	443	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
650743769	456	30.59	12	442	16	420	5.0e-45	175	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
650743770	401	40.99	1	399	1	398	2.0e-81	296	COG1228	Imidazolonepropionase or related amidohydrolase	406
650743771	501	62.65	1	489	11	498	0.0e+00	569	COG2986	Histidine ammonia-lyase	498
650743772	277	46.67	5	274	4	268	6.0e-81	294	COG3741	N-formylglutamate amidohydrolase	272
650743773	559	75.36	4	559	2	557	0.0e+00	966	COG2987	Urocanate hydratase	561
650743774	254	34.03	7	242	1	236	1.0e-47	183	COG2188	DNA-binding transcriptional regulator, GntR family	236
650743775	297	41.2	28	293	11	263	2.0e-57	215	COG3741	N-formylglutamate amidohydrolase	272
650743776	127	36.36	17	126	1	108	1.0e-18	85.3	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
650743778	1144	45.15	4	1140	12	1139	0.0e+00	1217	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
650743779	102	35.29	2	86	4	87	8.0e-14	68.7	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
650743780	687	46.99	6	659	2	664	0.0e+00	707	COG1200	RecG-like helicase	677
650743781	144	40.52	6	120	6	118	5.0e-18	83.9	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
650743782	325	35.56	23	299	2	271	1.0e-49	190	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
650743784	277	33.46	1	265	1	250	1.0e-42	167	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
650743785	435	44.44	27	427	16	411	1.0e-109	390	COG2262	50S ribosomal subunit-associated GTPase HflX	411
650743786	176	61.64	76	148	1	73	2.0e-29	122	COG1923	sRNA-binding regulator protein Hfq	77
650743790	345	40.17	1	344	4	352	7.0e-99	354	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
650743791	110	42.31	1	103	1	101	7.0e-18	82.4	COG0633	Ferredoxin	102
650743792	400	40.89	28	392	3	382	3.0e-82	299	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
650743793	255	63.43	6	180	7	181	7.0e-68	250	COG1045	Serine acetyltransferase	194
650743794	217	49.5	2	203	9	204	1.0e-61	229	COG2945	Alpha/beta superfamily hydrolase	210
650743795	265	36.29	10	257	6	253	8.0e-65	240	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
650743796	149	54.17	1	142	4	147	2.0e-46	178	COG4957	Predicted transcriptional regulator	148
650743797	87	25.68	13	86	5	78	9.0e-06	41.8	COG0425	TusA-related sulfurtransferase	78
650743798	148	32.45	12	143	22	172	3.0e-16	77.7	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
650743799	223	29.36	7	210	2	216	4.0e-16	78.2	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
650743800	194	21.29	4	190	1	201	1.0e-17	83.5	COG0778	Nitroreductase	207
650743801	185	49.41	102	184	1	85	2.0e-23	102	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
650743804	243	32.82	1	228	7	250	2.0e-15	76	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650743805	631	40.6	46	609	1	524	0.0e+00	528	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
650743807	220	36.45	11	210	1	203	1.0e-36	146	COG2518	Protein-L-isoaspartate O-methyltransferase	209
650743808	492	25.62	2	437	27	457	1.0e-40	161	COG1538	Outer membrane protein TolC	457
650743809	185	21.91	8	185	63	231	1.0e-09	56.2	COG3827	Cell pole-organizing protein PopZ	231
650743810	891	51.18	2	891	1	876	0.0e+00	1128	COG0525	Valyl-tRNA synthetase	877
650743811	276	31.25	23	256	1	239	7.0e-22	97.9	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
650743812	442	34.87	3	442	1	454	6.0e-83	301	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
650743813	417	40.48	1	407	17	436	4.0e-91	328	COG0612	Predicted Zn-dependent peptidase	438
650743814	467	30.77	1	461	1	411	1.0e-85	310	COG0498	Threonine synthase	411
650743815	166	34.94	1	166	5	154	2.0e-33	135	COG1952	Preprotein translocase subunit SecB	157
650743816	316	29.23	1	305	1	337	4.0e-62	231	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
650743817	182	38.59	1	177	1	179	7.0e-30	123	COG1514	2'-5' RNA ligase	180
650743818	499	41.12	5	486	1	472	1.0e-125	443	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650743819	295	28.33	1	291	1	297	8.0e-26	111	COG0583	DNA-binding transcriptional regulator, LysR family	297
650743821	337	27.9	1	274	19	287	1.0e-32	134	COG1566	Multidrug resistance efflux pump	352
650743822	579	50.9	332	550	4	225	1.0e-70	261	COG1131	ABC-type multidrug transport system, ATPase component	293
650743823	374	32.69	165	372	75	282	7.0e-20	91.9	COG0842	ABC-type multidrug transport system, permease component	286
650743824	368	30.62	161	368	76	284	2.0e-19	90	COG0842	ABC-type multidrug transport system, permease component	286
650743825	548	40.52	14	542	24	560	0.0e+00	482	COG1151	Hydroxylamine reductase (hybrid-cluster protein)	576
650743826	336	32.23	119	329	25	222	5.0e-34	138	COG0543	NAD(P)H-flavin reductase	252
650743827	150	45.11	1	131	1	133	1.0e-30	125	COG1959	DNA-binding transcriptional regulator, IscR family	150
650743828	376	24.28	30	366	39	375	5.0e-16	79.2	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
650743830	409	30.2	5	401	2	372	1.0e-32	134	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650743831	353	22.09	22	337	52	374	4.0e-07	49.2	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
650743832	372	27.3	1	368	3	373	2.0e-26	113	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650743833	368	28.34	7	356	3	374	2.0e-26	113	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650743835	614	28.22	1	600	23	537	2.0e-89	323	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
650743836	525	22.37	27	462	1	446	2.0e-22	100	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
650743839	317	28.67	8	297	3	302	2.0e-38	153	COG1216	Glycosyltransferase, GT2 family	305
650743840	292	27.12	1	286	1	305	4.0e-29	122	COG1216	Glycosyltransferase, GT2 family	305
650743841	356	21.92	8	327	17	345	7.0e-11	62.1	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
650743842	282	22.76	8	253	1	221	3.0e-08	52.7	COG2801	Transposase InsO and inactivated derivatives	232
650743844	793	16.28	3	793	6	768	2.0e-18	88.1	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
650743846	402	35.73	6	379	2	365	4.0e-73	268	COG3328	Transposase (or an inactivated derivative)	379
650743857	478	20.42	14	394	39	439	4.0e-13	69.7	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
650743858	470	17.65	51	439	31	428	1.0e-08	54.6	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
650743859	322	39.85	24	287	1	269	1.0e-56	213	COG1348	Nitrogenase subunit NifH, an ATPase	278
650743860	312	22	6	308	4	350	2.0e-20	93.2	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
650743861	375	21.24	207	375	54	235	5.0e-04	39.1	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
650743862	289	37.01	1	246	4	252	2.0e-39	156	COG0142	Geranylgeranyl pyrophosphate synthase	322
650743863	483	28.19	1	483	13	484	2.0e-45	176	COG1233	Phytoene dehydrogenase-related protein	487
650743865	352	34.74	1	280	3	286	6.0e-36	145	COG1562	Phytoene/squalene synthetase	288
650743866	509	33.2	16	495	2	472	4.0e-78	285	COG1233	Phytoene dehydrogenase-related protein	487
650743867	307	28.42	31	302	1	282	7.0e-13	68.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650743868	566	38.26	303	561	17	257	9.0e-27	115	COG1240	Mg-chelatase subunit ChlD	261
650743869	340	54.44	4	340	14	351	3.0e-93	335	COG1239	Mg-chelatase subunit ChlI	423
650743870	168	36.91	11	159	10	158	5.0e-23	100	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
650743871	397	29.37	6	384	3	383	2.0e-37	150	COG0644	Dehydrogenase (flavoprotein)	396
650743872	309	26.79	28	305	17	287	3.0e-22	99.6	COG0382	4-hydroxybenzoate polyprenyltransferase	289
650743874	290	20.95	74	278	19	221	2.0e-07	49.9	COG5012	Methanogenic corrinoid protein MtbC1	227
650743876	422	19.44	37	407	47	428	2.0e-15	77.4	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
650743877	522	24.03	12	405	36	430	3.0e-26	113	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
650743879	307	41.48	42	304	2	267	4.0e-69	255	COG1348	Nitrogenase subunit NifH, an ATPase	278
650743887	620	30.05	259	614	3	320	3.0e-50	193	COG0523	GTPase, G3E family	323
650743888	403	47.1	1	394	1	388	1.0e-120	426	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
650743891	225	33.91	12	125	7	119	3.0e-16	78.5	COG2863	Cytochrome c553	121
650743892	289	36.9	10	288	3	292	1.0e-63	236	COG3258	Cytochrome c	293
650743894	337	24.9	84	331	31	254	2.0e-17	83.5	COG0725	ABC-type molybdate transport system, periplasmic component	258
650743895	192	23.71	89	185	1	93	1.0e-04	40.1	COG3293	Transposase	124
650743896	94	29.47	2	92	7	101	1.0e-07	48.2	COG3293	Transposase	124
650743898	347	25.6	39	328	26	303	7.0e-28	118	COG3547	Transposase	303
650743899	275	30.71	17	139	1	124	2.0e-12	66.7	COG3293	Transposase	124
650743900	253	35.83	11	248	2	228	8.0e-50	190	COG2063	Flagellar basal body L-ring protein FlgH	230
650743902	260	49.24	1	260	2	263	1.0e-70	260	COG4786	Flagellar basal body rod protein FlgG	265
650743903	247	31.82	1	241	1	264	3.0e-40	158	COG4786	Flagellar basal body rod protein FlgG	265
650743905	428	22.03	35	376	26	350	1.0e-07	51.1	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
650743906	1037	37.37	1	1009	1	1064	0.0e+00	960	COG0587	DNA polymerase III, alpha subunit	1139
650743907	170	23.27	22	170	7	159	8.0e-08	50.3	COG1580	Flagellar basal body-associated protein FliL	159
650743908	226	24.84	57	217	33	192	5.0e-11	61.6	COG3334	Flagellar motility protein MotE, a chaperone for MotC folding	192
650743915	321	24.5	12	309	1	296	9.0e-22	97.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
650743917	318	26.16	21	313	19	291	1.0e-14	74.3	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
650743918	258	32.46	143	255	7	120	1.0e-14	73.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650743919	271	23.53	1	271	4	252	2.0e-07	50	COG0730	Uncharacterized membrane protein YfcA	258
650743924	148	32.89	1	146	3	151	3.0e-21	94.4	COG1522	DNA-binding transcriptional regulator, Lrp family	154
650743925	319	36.77	7	313	17	304	1.0e-56	213	COG0010	Arginase family enzyme	305
650743926	356	39.64	5	328	1	330	4.0e-88	318	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
650743927	308	33.33	12	273	7	261	9.0e-19	87.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650743928	149	30.97	3	144	2	150	1.0e-17	82.7	COG4539	Uncharacterized membrane protein YGL010W	180
650743929	573	43.08	125	572	12	445	1.0e-108	387	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
650743930	402	36.13	6	386	2	371	1.0e-73	270	COG3328	Transposase (or an inactivated derivative)	379
650743935	252	30.83	126	244	1	120	2.0e-17	83	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650743936	250	33.16	1	184	6	199	1.0e-34	140	COG0300	Short-chain dehydrogenase	265
650743937	315	38.41	12	303	15	311	4.0e-39	155	COG0657	Acetyl esterase/lipase	312
650743938	292	28.11	1	273	1	275	3.0e-22	99.2	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
650743939	299	30.3	1	294	1	295	2.0e-28	119	COG0583	DNA-binding transcriptional regulator, LysR family	297
650743946	340	24.7	1	332	3	293	6.0e-18	85.5	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
650743947	434	19.68	10	434	21	447	2.0e-21	97.6	COG2271	Sugar phosphate permease	448
650743948	226	39.81	17	222	10	210	9.0e-41	160	COG0684	Regulator of RNase E activity RraA	210
650743949	302	38.87	1	298	1	292	3.0e-37	149	COG0583	DNA-binding transcriptional regulator, LysR family	297
650743951	288	28.83	21	287	3	278	1.0e-35	143	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
650743952	1214	51.6	702	1214	2	522	0.0e+00	623	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
650743953	197	45.41	2	196	5	198	8.0e-50	189	COG5631	Predicted transcription regulator, contains HTH domain, MarR family	199
650743954	421	27.66	42	415	26	387	5.0e-15	76	COG2814	Predicted arabinose efflux permease, MFS family	394
650743956	291	42.62	7	248	4	247	3.0e-59	222	COG1484	DNA replication protein DnaC	254
650743962	298	44.23	215	266	5	56	4.0e-08	52.7	COG2771	DNA-binding transcriptional regulator, CsgD family	65
650743963	521	21.25	20	493	2	455	2.0e-28	120	COG0531	Amino acid transporter	466
650743964	255	35.97	3	249	1	247	1.0e-34	140	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650743968	152	34.01	7	149	5	151	6.0e-21	93.6	COG1522	DNA-binding transcriptional regulator, Lrp family	154
650743969	103	19.19	1	98	13	107	6.0e-05	39.2	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
650743970	292	34.29	189	292	18	122	2.0e-21	96.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650743971	307	20	1	284	7	286	6.0e-04	38.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
650743972	455	28.6	4	439	11	447	2.0e-49	190	COG2079	2-methylcitrate dehydratase PrpD	453
650743973	413	45.93	17	394	1	376	1.0e-95	343	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
650743974	252	31.35	2	242	5	248	2.0e-34	139	COG1809	Phosphosulfolactate synthase, CoM biosynthesis protein A	258
650743975	312	24.51	9	258	2	247	5.0e-24	105	COG1378	Sugar-specific transcriptional regulator TrmB	247
650743976	557	20.83	5	523	3	438	4.0e-23	103	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
650743978	322	29.1	56	319	69	335	6.0e-32	131	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
650743979	272	31.92	4	263	1	253	9.0e-37	147	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
650743980	275	34.17	30	269	17	252	2.0e-34	139	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
650743981	288	48.79	33	280	3	243	1.0e-81	296	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
650743983	252	23.35	2	226	27	231	5.0e-12	65	COG2801	Transposase InsO and inactivated derivatives	232
650743989	380	37.28	79	364	92	371	4.0e-59	222	COG3328	Transposase (or an inactivated derivative)	379
650743993	566	22.49	2	204	6	196	6.0e-15	76.3	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650743996	359	25.86	50	164	48	160	3.0e-06	46.6	COG3666	Transposase	161
650744004	338	30.67	4	325	1	303	1.0e-34	140	COG3547	Transposase	303
650744005	128	36.8	1	123	1	124	2.0e-12	65	COG3415	Transposase	138
650744006	346	31.21	4	329	1	303	4.0e-28	118	COG3547	Transposase	303
650744007	577	17.04	67	479	10	432	5.0e-26	112	COG5421	Transposase	480
650744008	157	33.33	25	154	1	132	7.0e-15	73.5	COG3335	Transposase	132
650744011	301	34.01	7	283	2	292	5.0e-48	185	COG4974	Site-specific recombinase XerD	300
650744013	634	19.3	73	378	2	313	4.0e-13	70.1	COG1106	ATPase/GTPase, AAA15 family	371
650744016	236	37.14	97	236	1	138	3.0e-22	99	COG3436	Transposase	157
650744022	546	21.05	2	204	18	208	8.0e-14	72.5	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650744024	279	30.77	5	257	10	265	5.0e-23	101	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
650744030	212	45.36	1	190	61	254	1.0e-42	166	COG1484	DNA replication protein DnaC	254
650744035	399	36.24	19	384	15	371	6.0e-78	284	COG3328	Transposase (or an inactivated derivative)	379
650744036	133	26.02	3	125	1	120	3.0e-07	47.4	COG3293	Transposase	124
650744037	115	22.88	1	114	1	116	4.0e-08	50.1	COG3293	Transposase	124
650744038	346	31.21	4	329	1	303	4.0e-28	118	COG3547	Transposase	303
650744040	349	32.48	28	334	16	303	2.0e-29	123	COG3547	Transposase	303
650744042	540	43.52	1	534	3	530	0.0e+00	541	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
650744043	544	21.05	2	204	18	208	9.0e-14	72.1	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650744050	860	58.08	5	853	1	782	0.0e+00	972	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
650744051	253	25.47	3	253	2	263	1.0e-23	103	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
650744052	194	41.97	1	191	10	192	5.0e-20	90.8	COG0558	Phosphatidylglycerophosphate synthase	192
650744053	179	42.94	13	172	2	161	7.0e-35	140	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
650744055	83	33.73	1	83	2	84	9.0e-16	75.4	COG1977	Molybdopterin converting factor, small subunit	84
650744056	152	46.31	5	151	2	149	1.0e-37	148	COG0314	Molybdopterin synthase catalytic subunit	149
650744057	250	31.14	1	222	1	227	2.0e-30	126	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650744058	383	27.67	22	310	13	310	2.0e-24	107	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
650744059	321	63.82	14	305	2	294	1.0e-114	406	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
650744060	647	58.25	5	631	2	624	0.0e+00	888	COG1154	Deoxyxylulose-5-phosphate synthase	627
650744061	204	23.41	1	198	6	202	7.0e-15	74.2	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
650744062	397	22.65	22	378	34	384	4.0e-19	89.2	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
650744064	267	30.21	7	237	5	212	2.0e-24	106	COG3394	Predicted glycoside hydrolase or deacetylase ChbG, UPF0249 family	257
650744066	148	33.82	15	148	13	148	4.0e-17	80.7	COG1981	Uncharacterized membrane protein	149
650744067	110	41.54	4	64	5	67	2.0e-08	50.9	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
650744068	242	45.21	13	229	3	221	6.0e-59	220	COG2846	Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains	221
650744069	139	27.35	8	121	16	132	2.0e-15	75.3	COG2346	Truncated hemoglobin YjbI	133
650744070	139	44.96	5	132	3	130	6.0e-27	113	COG1959	DNA-binding transcriptional regulator, IscR family	150
650744071	571	32.12	7	496	37	513	2.0e-94	340	COG0513	Superfamily II DNA and RNA helicase	513
650744072	218	50.93	5	217	1	213	4.0e-66	244	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
650744073	228	49.32	2	222	1	219	4.0e-60	224	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
650744074	400	44.04	1	400	1	392	1.0e-80	293	COG0183	Acetyl-CoA acetyltransferase	392
650744075	173	37.84	4	173	45	226	2.0e-28	118	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
650744076	234	44.1	6	234	5	225	2.0e-55	209	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
650744077	398	27.85	6	388	2	387	6.0e-44	171	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
650744078	728	76.58	1	728	12	730	0.0e+00	1189	COG0376	Catalase (peroxidase I)	730
650744079	330	42.99	19	330	1	313	1.0e-53	203	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650744080	339	32.2	1	319	2	312	3.0e-39	156	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650744082	250	37.07	3	242	1	251	1.0e-31	129	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650744083	272	28.47	1	272	8	278	7.0e-44	170	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
650744084	297	36.06	30	294	39	296	3.0e-28	119	COG0524	Sugar or nucleoside kinase, ribokinase family	311
650744085	393	48.71	1	388	1	357	8.0e-121	427	COG1312	D-mannonate dehydratase	362
650744086	470	45.64	20	414	1	396	2.0e-108	386	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
650744087	257	45.63	15	254	3	250	2.0e-32	133	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650744088	264	35.05	36	248	18	230	7.0e-33	134	COG1802	DNA-binding transcriptional regulator, GntR family	230
650744089	503	50.87	101	503	2	381	0.0e+00	480	COG2721	Altronate dehydratase	381
650744090	238	53.62	1	234	3	236	2.0e-81	295	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650744091	599	52.99	345	593	2	249	1.0e-81	297	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650744092	294	44.3	1	293	2	297	3.0e-50	192	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650744093	373	33.33	21	359	4	349	8.0e-47	181	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650744094	223	35.51	1	214	2	208	4.0e-39	155	COG0132	Dethiobiotin synthetase	223
650744095	381	45.83	4	375	3	386	4.0e-103	368	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
650744096	325	55.88	19	322	15	318	6.0e-113	400	COG0502	Biotin synthase or related enzyme	335
650744097	418	43.34	1	417	2	443	4.0e-128	451	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
650744099	231	40.62	9	229	4	227	3.0e-25	108	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
650744101	205	37.43	9	174	8	178	2.0e-22	98.8	COG3038	Cytochrome b561	181
650744102	458	52.97	7	457	2	455	0.0e+00	475	COG3572	Gamma-glutamylcysteine synthetase	456
650744103	226	36.05	1	221	12	242	1.0e-40	160	COG1385	16S rRNA U1498 N3-methylase RsmE	246
650744104	309	41.75	26	309	5	288	3.0e-40	158	COG0382	4-hydroxybenzoate polyprenyltransferase	289
650744105	214	47.85	3	210	8	216	1.0e-48	186	COG3897	Predicted nicotinamide N-methyase	218
650744106	147	47.24	25	146	3	129	1.0e-17	82.3	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
650744107	122	32.48	5	121	1	117	2.0e-16	78.3	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
650744108	603	53.28	14	586	2	561	0.0e+00	624	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
650744109	260	54.89	26	259	1	231	2.0e-83	302	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
650744111	549	31.72	220	548	17	329	1.0e-38	154	COG0642	Signal transduction histidine kinase	336
650744112	233	46.52	5	232	3	227	2.0e-55	209	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650744113	239	27	15	236	6	235	2.0e-16	80	COG0748	Putative heme iron utilization protein	245
650744114	541	58.81	15	536	6	525	0.0e+00	731	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
650744116	389	49.74	5	389	5	391	2.0e-116	412	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
650744117	229	28.44	8	218	4	195	2.0e-23	102	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
650744118	182	34.75	19	136	5	122	1.0e-12	66.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
650744119	368	34.81	26	359	7	341	2.0e-60	226	COG1566	Multidrug resistance efflux pump	352
650744120	524	18.88	43	418	36	351	1.0e-15	78.7	COG2814	Predicted arabinose efflux permease, MFS family	394
650744121	210	59.13	4	210	3	210	1.0e-77	282	COG0035	Uracil phosphoribosyltransferase	210
650744122	460	16.75	1	406	1	380	1.0e-21	97.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650744124	950	25.27	298	568	5	265	2.0e-24	108	COG1216	Glycosyltransferase, GT2 family	305
650744125	591	28.51	137	365	3	237	9.0e-19	89	COG0790	TPR repeat	292
650744126	476	19.49	54	402	14	294	2.0e-08	54.2	COG1566	Multidrug resistance efflux pump	352
650744127	742	34.48	28	722	21	709	0.0e+00	536	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
650744128	167	45.83	1	167	2	168	2.0e-41	161	COG1247	L-amino acid N-acyltransferase YncA	169
650744129	289	34.4	1	282	3	261	4.0e-52	198	COG1291	Flagellar motor component MotA	266
650744131	327	44.17	1	324	3	325	1.0e-81	297	COG1171	Threonine dehydratase	347
650744133	365	26.42	6	270	2	255	4.0e-18	86	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
650744134	161	51.83	1	159	2	165	1.0e-56	212	COG0678	Peroxiredoxin	165
650744135	229	37.95	43	228	56	250	3.0e-44	171	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
650744136	159	49.31	16	159	9	151	5.0e-44	170	COG0691	tmRNA-binding protein	153
650744137	292	54.58	1	292	4	298	9.0e-93	333	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
650744138	677	28.71	353	667	2	292	8.0e-19	89.4	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
650744139	160	38.62	14	152	18	160	8.0e-15	73.4	COG1267	Phosphatidylglycerophosphatase A	160
650744140	157	59.21	5	156	10	160	4.0e-43	167	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
650744141	554	36.65	285	531	5	254	2.0e-51	197	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
650744142	170	28.16	1	170	5	178	2.0e-11	62.2	COG2059	Chromate transport protein ChrA	195
650744143	181	31.64	6	179	3	177	2.0e-19	88.7	COG2059	Chromate transport protein ChrA	195
650744145	359	32.3	1	347	3	318	2.0e-44	173	COG0226	ABC-type phosphate transport system, periplasmic component	318
650744146	324	40.45	7	317	21	305	4.0e-52	198	COG0573	ABC-type phosphate transport system, permease component	310
650744147	286	43.55	5	284	1	287	5.0e-53	201	COG0581	ABC-type phosphate transport system, permease component	292
650744148	158	34.29	20	157	16	155	9.0e-20	89.5	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
650744149	132	36.59	6	128	6	123	2.0e-13	68	COG3788	Uncharacterized membrane protein YecN, MAPEG domain	131
650744150	554	22.75	35	552	55	590	4.0e-68	252	COG1164	Oligoendopeptidase F	598
650744151	127	64.95	1	97	20	116	8.0e-37	145	COG0203	Ribosomal protein L17	116
650744152	339	52.66	12	330	3	317	9.0e-99	353	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
650744153	130	64.62	1	130	1	129	1.0e-44	171	COG0100	Ribosomal protein S11	129
650744154	125	65.29	1	121	1	121	4.0e-41	160	COG0099	Ribosomal protein S13	121
650744155	224	40.65	1	214	1	178	1.0e-49	189	COG0563	Adenylate kinase or related kinase	178
650744156	449	50	13	440	9	432	1.0e-117	416	COG0201	Preprotein translocase subunit SecY	436
650744157	161	47.13	1	152	1	151	8.0e-27	113	COG0200	Ribosomal protein L15	152
650744158	64	43.64	8	62	1	55	2.0e-10	57.4	COG1841	Ribosomal protein L30/L7E	55
650744159	189	59.54	6	178	8	180	5.0e-55	207	COG0098	Ribosomal protein S5	181
650744160	120	53.91	8	120	12	125	1.0e-28	118	COG0256	Ribosomal protein L18	125
650744161	163	50	2	162	16	176	2.0e-47	181	COG0097	Ribosomal protein L6P/L9E	178
650744162	132	54.14	1	132	1	132	1.0e-44	171	COG0096	Ribosomal protein S8	132
650744163	101	52.46	41	101	1	61	6.0e-14	69.1	COG0199	Ribosomal protein S14	61
650744164	185	66.1	9	185	3	179	7.0e-74	269	COG0094	Ribosomal protein L5	180
650744165	106	58.49	1	105	1	104	3.0e-21	93.4	COG0198	Ribosomal protein L24	104
650744166	122	72.13	1	122	1	122	4.0e-45	173	COG0093	Ribosomal protein L14	122
650744167	90	61.64	1	73	6	78	5.0e-24	102	COG0186	Ribosomal protein S17	87
650744168	68	47.76	1	67	2	68	2.0e-09	53.7	COG0255	Ribosomal protein L29	69
650744169	138	61.87	1	137	2	140	8.0e-47	179	COG0197	Ribosomal protein L16/L10AE	146
650744170	225	62.04	12	225	1	216	4.0e-76	277	COG0092	Ribosomal protein S3	233
650744171	153	51.38	14	122	10	118	2.0e-24	104	COG0091	Ribosomal protein L22	120
650744172	92	61.96	1	91	1	92	1.0e-34	137	COG0185	Ribosomal protein S19	93
650744173	277	61.68	1	273	1	274	3.0e-105	374	COG0090	Ribosomal protein L2	275
650744174	113	61.96	21	110	1	92	3.0e-23	100	COG0089	Ribosomal protein L23	94
650744175	216	45.93	1	203	2	210	5.0e-48	184	COG0088	Ribosomal protein L4	214
650744176	225	51.83	3	217	1	218	6.0e-70	257	COG0087	Ribosomal protein L3	218
650744177	102	73.53	1	102	1	102	3.0e-38	149	COG0051	Ribosomal protein S10	104
650744178	395	80.3	1	395	1	394	0.0e+00	696	COG0050	Translation elongation factor EF-Tu, a GTPase	394
650744179	158	66	2	151	1	148	4.0e-56	210	COG0049	Ribosomal protein S7	148
650744180	123	73.17	1	123	7	129	7.0e-47	178	COG0048	Ribosomal protein S12	129
650744181	1388	50.88	20	845	7	806	0.0e+00	898	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
650744183	127	63.78	1	127	2	124	4.0e-26	110	COG0222	Ribosomal protein L7/L12	124
650744184	178	44.58	7	170	5	170	3.0e-32	131	COG0244	Ribosomal protein L10	175
650744185	230	63.16	1	226	1	228	6.0e-80	290	COG0081	Ribosomal protein L1	228
650744186	144	64.54	2	142	1	139	2.0e-49	187	COG0080	Ribosomal protein L11	141
650744187	232	34.68	16	232	1	213	9.0e-39	153	COG3047	Outer membrane protein W	213
650744188	326	42.14	1	313	1	315	3.0e-88	318	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650744189	466	40.38	2	460	9	466	3.0e-120	425	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
650744190	280	32.67	14	259	7	245	2.0e-41	163	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
650744191	354	39.68	42	348	1	310	1.0e-69	257	COG0167	Dihydroorotate dehydrogenase	310
650744193	281	43.59	10	277	1	261	3.0e-69	255	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
650744194	441	43.94	14	441	12	444	0.0e+00	473	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
650744195	476	46.82	5	474	1	467	0.0e+00	467	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650744196	265	28.52	10	263	59	317	7.0e-41	161	COG0616	Periplasmic serine protease, ClpP class	317
650744197	141	44.14	2	140	3	144	1.0e-27	115	COG5458	Uncharacterized protein	144
650744198	770	38.6	8	766	8	731	0.0e+00	537	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
650744200	365	28.74	23	347	112	441	4.0e-25	109	COG1231	Monoamine oxidase	450
650744201	402	38.52	25	395	18	393	3.0e-60	225	COG4214	ABC-type xylose transport system, permease component	394
650744203	369	41.23	20	356	6	341	2.0e-70	260	COG4213	ABC-type xylose transport system, periplasmic component	341
650744205	623	62.3	94	589	1	495	0.0e+00	645	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
650744207	222	33.99	3	203	2	201	1.0e-27	116	COG0625	Glutathione S-transferase	211
650744208	416	28.25	13	277	4	238	1.0e-33	137	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
650744210	603	33.91	2	403	8	397	1.0e-48	188	COG0475	Kef-type K+ transport system, membrane component KefB	397
650744211	521	37.22	61	502	1	454	2.0e-108	386	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
650744212	468	68.31	11	455	2	444	0.0e+00	703	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
650744213	383	21.88	22	375	17	354	7.0e-19	88.8	COG1488	Nicotinic acid phosphoribosyltransferase	405
650744214	115	29.91	1	107	20	124	2.0e-09	54.2	COG3753	Uncharacterized conserved protein YidB, DUF937 family	143
650744216	554	37.59	262	542	2	268	3.0e-68	253	COG0171	NH3-dependent NAD+ synthetase	268
650744218	89	39.33	1	89	2	90	2.0e-12	64	COG0776	Bacterial nucleoid DNA-binding protein	94
650744221	87	51.19	1	83	1	84	2.0e-20	90.7	COG0851	Septum formation topological specificity factor MinE	88
650744222	271	62.73	1	269	1	270	3.0e-111	394	COG2894	Septum formation inhibitor-activating ATPase MinD	272
650744223	227	37.56	7	226	16	217	9.0e-44	170	COG0850	Septum formation inhibitor MinC	219
650744224	327	31.96	2	316	1	337	1.0e-32	133	COG0673	Predicted dehydrogenase	342
650744225	526	43.37	1	525	1	506	9.0e-119	420	COG0342	Preprotein translocase subunit SecD	506
650744226	342	43.28	26	330	2	304	8.0e-78	284	COG0341	Preprotein translocase subunit SecF	305
650744228	224	27.54	36	224	11	213	2.0e-08	53	COG2755	Lysophospholipase L1 or related esterase	216
650744229	368	29.48	8	357	22	372	2.0e-32	133	COG4645	Uncharacterized protein	410
650744230	196	49.23	1	193	2	196	7.0e-61	226	COG0353	Recombinational DNA repair protein RecR	198
650744231	107	55.77	1	104	4	105	1.0e-23	101	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
650744232	614	42.59	42	507	2	478	3.0e-120	426	COG2812	DNA polymerase III, gamma/tau subunits	515
650744234	319	42.81	33	316	1	267	1.0e-63	237	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
650744235	199	43.9	1	197	3	205	2.0e-44	172	COG0655	Multimeric flavodoxin WrbA	207
650744240	342	46.01	17	333	1	318	2.0e-63	236	COG0714	MoxR-like ATPase	329
650744241	223	47.34	48	216	32	195	9.0e-42	163	COG3816	Uncharacterized protein	205
650744243	403	29.74	31	393	24	406	5.0e-56	211	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
650744244	225	53.2	23	222	1	203	7.0e-67	247	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
650744247	794	25.37	19	794	69	859	0.0e+00	623	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
650744248	199	27.36	1	105	1	105	2.0e-16	79.1	COG1544	Ribosome-associated translation inhibitor RaiA	110
650744249	490	39.83	5	484	3	444	3.0e-122	432	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
650744250	307	29.81	2	307	8	318	9.0e-17	81.4	COG2064	Pilus assembly protein TadC	320
650744251	319	31.09	7	318	1	309	4.0e-31	129	COG4965	Flp pilus assembly protein TadB	309
650744252	444	56.4	61	404	17	355	6.0e-115	408	COG4962	Pilus assembly protein, ATPase of CpaF family	355
650744254	275	30.42	3	234	4	236	2.0e-23	103	COG3745	Flp pilus assembly protein CpaB	276
650744255	63	51.06	16	62	8	54	7.0e-05	39.1	COG3847	Flp pilus assembly protein, pilin Flp	58
650744256	330	32.82	7	326	1	304	4.0e-38	152	COG0524	Sugar or nucleoside kinase, ribokinase family	311
650744257	156	26.92	47	150	25	128	4.0e-12	64.2	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
650744259	317	36.62	4	314	1	316	1.0e-63	237	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
650744261	279	31.42	17	272	5	231	1.0e-42	166	COG0860	N-acetylmuramoyl-L-alanine amidase	231
650744262	138	36.92	5	133	4	132	1.0e-17	82.7	COG4852	Uncharacterized membrane protein	134
650744263	487	45.82	13	348	6	347	7.0e-101	361	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
650744265	172	60.39	13	166	1	154	1.0e-56	212	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
650744266	353	46.2	25	337	6	317	2.0e-84	306	COG0042	tRNA-dihydrouridine synthase	323
650744267	381	40.11	23	379	8	361	1.0e-87	317	COG3852	Signal transduction histidine kinase, nitrogen specific	363
650744268	487	47.64	1	484	1	460	0.0e+00	511	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
650744269	740	39.97	30	737	9	706	0.0e+00	566	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
650744270	465	47.31	1	464	4	464	0.0e+00	489	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
650744271	821	17.16	18	821	3	768	6.0e-26	113	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
650744272	162	39.88	3	162	1	167	6.0e-32	130	COG0629	Single-stranded DNA-binding protein	167
650744273	341	41.86	1	336	1	340	3.0e-66	245	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
650744274	472	42.26	10	455	4	455	2.0e-115	409	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
650744275	213	46.33	1	177	2	176	8.0e-48	183	COG1510	DNA-binding transcriptional regulator GbsR, MarR family	177
650744276	303	40	1	292	1	295	3.0e-65	242	COG3781	Predicted membrane chloride channel, bestrophin family	306
650744277	304	33.44	1	299	6	297	1.0e-36	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
650744278	765	24.37	4	762	1	765	1.0e-97	350	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
650744280	957	65.71	4	944	3	935	0.0e+00	1513	COG0178	Excinuclease UvrABC ATPase subunit	935
650744281	334	25.07	3	331	1	333	2.0e-32	133	COG1466	DNA polymerase III, delta subunit	334
650744282	172	28.24	1	162	1	166	2.0e-11	62	COG5468	Predicted secreted (periplasmic) protein	172
650744283	864	46.87	7	862	1	814	0.0e+00	952	COG0495	Leucyl-tRNA synthetase	814
650744286	200	29.63	21	192	6	190	3.0e-14	71.9	COG0352	Thiamine monophosphate synthase	211
650744287	229	44.05	12	225	1	226	2.0e-61	228	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
650744288	326	33.54	15	326	11	324	2.0e-50	192	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
650744289	425	31.64	11	419	1	413	4.0e-69	255	COG2733	Uncharacterized membrane-anchored protein YjiN, DUF445 family	415
650744290	445	39.42	5	404	13	405	5.0e-87	315	COG1488	Nicotinic acid phosphoribosyltransferase	405
650744291	447	39.32	25	339	19	337	5.0e-71	261	COG2187	Aminoglycoside phosphotransferase family enzyme	337
650744292	319	35.99	6	317	5	305	1.0e-64	240	COG0462	Phosphoribosylpyrophosphate synthetase	314
650744294	221	54.98	1	210	3	211	3.0e-50	191	COG1926	Predicted phosphoribosyltransferase	220
650744295	146	29.01	11	141	7	135	5.0e-17	80.3	COG5502	Uncharacterized conserved protein, DUF2267 family	135
650744297	403	22.56	7	393	4	384	6.0e-11	62.1	COG2814	Predicted arabinose efflux permease, MFS family	394
650744298	801	27.33	3	784	72	863	0.0e+00	662	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
650744299	156	47.55	7	149	6	147	1.0e-30	125	COG1522	DNA-binding transcriptional regulator, Lrp family	154
650744301	421	23.64	3	407	25	437	5.0e-27	116	COG2271	Sugar phosphate permease	448
650744302	413	30	22	408	4	367	3.0e-54	206	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
650744303	416	43.48	5	416	7	395	2.0e-104	372	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
650744304	495	25.4	24	328	1	275	5.0e-18	86.1	COG0492	Thioredoxin reductase	305
650744305	392	32.9	8	366	5	382	2.0e-39	157	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
650744306	372	24.02	1	367	2	379	8.0e-24	104	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
650744307	320	24.59	12	311	1	297	1.0e-26	113	COG0583	DNA-binding transcriptional regulator, LysR family	297
650744308	676	43.89	20	334	2	315	2.0e-96	347	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
650744309	283	41.42	17	283	16	283	6.0e-60	224	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
650744310	321	37.97	5	318	1	316	3.0e-66	245	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
650744314	395	29.74	117	373	24	291	3.0e-23	102	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
650744315	283	24.19	31	277	30	271	2.0e-22	100	COG3176	Putative hemolysin	292
650744317	205	35.75	3	204	2	208	2.0e-22	99.2	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
650744318	420	31.36	17	419	14	414	4.0e-58	219	COG2995	Uncharacterized paraquat-inducible protein A	418
650744319	541	25.13	1	539	4	540	2.0e-55	210	COG3008	Paraquat-inducible protein B	553
650744320	184	23.91	8	184	5	188	2.0e-08	52.7	COG3009	Uncharacterized lipoprotein YmbA	190
650744321	239	39.51	9	239	12	251	1.0e-51	196	COG0631	Serine/threonine protein phosphatase PrpC	262
650744323	1175	36.12	1	1172	6	1185	0.0e+00	772	COG3523	Type VI protein secretion system component VasK	1188
650744324	456	40.84	19	280	1	254	2.0e-54	207	COG3455	Type VI protein secretion system component VasF	262
650744325	443	51.12	1	443	1	446	0.0e+00	487	COG3522	Predicted component of the type VI protein secretion system	446
650744326	156	32.26	3	156	6	158	1.0e-21	95.7	COG3521	Predicted component of the type VI protein secretion system	159
650744327	463	29.53	1	455	1	424	6.0e-49	188	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
650744329	646	33.21	1	543	6	548	5.0e-107	382	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
650744330	575	24.5	5	544	10	529	2.0e-49	190	COG2831	Hemolysin activation/secretion protein	554
650744332	1024	24.42	595	1017	35	420	5.0e-33	137	COG4995	Uncharacterized conserved protein, contains CHAT domain	420
650744333	620	32.79	11	294	1	302	8.0e-49	188	COG0515	Serine/threonine protein kinase	384
650744334	123	42.86	8	123	15	132	3.0e-24	103	COG3474	Cytochrome c2	135
650744336	610	48.73	18	606	6	585	0.0e+00	690	COG0514	Superfamily II DNA helicase RecQ	590
650744337	219	32.08	1	205	2	213	1.0e-27	116	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
650744338	431	61.48	1	430	1	426	0.0e+00	565	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
650744339	887	36.91	11	878	9	858	0.0e+00	562	COG0308	Aminopeptidase N	859
650744340	382	57.22	6	379	6	386	0.0e+00	469	COG3146	Predicted N-acyltransferase	387
650744341	288	24.11	4	281	13	288	2.0e-10	59.9	COG5006	Threonine/homoserine efflux transporter RhtA	292
650744342	133	43.86	8	64	3	59	4.0e-07	47.2	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
650744343	537	23.94	6	447	39	496	2.0e-23	104	COG0833	Amino acid permease	541
650744345	199	30.58	1	199	1	206	2.0e-22	99.1	COG0625	Glutathione S-transferase	211
650744346	353	35.08	12	331	2	309	8.0e-59	221	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
650744347	426	33.67	1	394	1	384	4.0e-65	242	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650744348	324	45.73	1	324	1	326	3.0e-82	298	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
650744349	292	35.23	1	193	1	188	4.0e-35	141	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
650744350	312	41.88	1	312	2	317	6.0e-64	237	COG0611	Thiamine monophosphate kinase	317
650744351	165	36	9	158	8	149	4.0e-21	94.2	COG0781	Transcription termination factor NusB	151
650744352	160	37.16	12	156	6	152	7.0e-28	116	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
650744353	375	60.4	13	214	3	203	5.0e-77	281	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
650744354	204	47.29	1	202	1	193	2.0e-63	235	COG0307	Riboflavin synthase alpha chain	204
650744355	363	60.56	2	143	5	146	2.0e-48	186	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
650744356	151	59.72	1	144	1	144	3.0e-50	190	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
650744357	432	67.06	13	431	2	412	0.0e+00	656	COG0112	Glycine/serine hydroxymethyltransferase	413
650744358	150	49.65	5	145	1	143	2.0e-39	155	COG0698	Ribose 5-phosphate isomerase RpiB	151
650744360	61	60	7	61	1	55	4.0e-15	72.9	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
650744361	120	63.79	4	119	3	118	2.0e-39	154	COG3536	Uncharacterized conserved protein, DUF971 family	120
650744362	311	38.71	5	310	7	304	3.0e-56	212	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
650744363	217	40.49	12	213	9	207	3.0e-35	142	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
650744364	324	33.44	2	316	34	350	3.0e-62	232	COG1377	Flagellar biosynthesis protein FlhB	363
650744365	259	28.46	6	258	8	252	2.0e-21	96.4	COG1684	Flagellar biosynthesis protein FliR	258
650744366	88	45.12	1	82	1	82	1.0e-10	57.8	COG1987	Flagellar biosynthesis protein FliQ	89
650744367	100	27.08	6	100	10	105	9.0e-10	55.3	COG1677	Flagellar hook-basal body complex protein FliE	105
650744368	134	44.85	1	133	1	135	3.0e-36	144	COG1558	Flagellar basal body rod protein FlgC	137
650744369	126	28.57	4	122	6	130	3.0e-11	60.7	COG1815	Flagellar basal body rod protein FlgB	133
650744370	253	46.77	1	248	1	247	2.0e-66	245	COG1338	Flagellar biosynthetic protein FliP	248
650744371	465	25.38	145	464	10	331	7.0e-28	118	COG0642	Signal transduction histidine kinase	336
650744372	326	23.33	28	325	11	281	5.0e-25	108	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
650744374	120	36.27	8	108	6	105	5.0e-11	59.9	COG0594	RNase P protein component	117
650744375	84	53.52	5	75	7	77	7.0e-25	105	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
650744376	601	37.73	267	585	3	295	2.0e-61	230	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
650744377	209	44.04	12	204	1	192	2.0e-54	205	COG0218	GTP-binding protein EngB required for normal cell division	200
650744378	299	54.04	28	297	1	263	2.0e-81	295	COG0548	Acetylglutamate kinase	265
650744379	556	34.89	163	542	2	408	4.0e-47	183	COG0840	Methyl-accepting chemotaxis protein	408
650744380	430	39.91	1	424	1	421	7.0e-95	341	COG1253	Hemolysin or related protein, contains CBS domains	429
650744381	903	31.74	35	316	14	305	3.0e-53	204	COG5309	Exo-beta-1,3-glucanase,  GH17 family	305
650744382	370	51.62	3	368	2	348	1.0e-115	409	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
650744383	207	56.28	2	200	1	191	1.0e-72	265	COG0066	3-isopropylmalate dehydratase small subunit	191
650744384	466	57.23	1	466	1	423	0.0e+00	609	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
650744385	124	61.21	1	116	3	113	1.0e-37	148	COG0335	Ribosomal protein L19	115
650744386	234	52.65	3	226	1	226	3.0e-90	324	COG0336	tRNA G37 N-methylase TrmD	240
650744387	169	31.76	3	159	5	166	6.0e-24	103	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
650744388	114	65.85	2	83	1	80	3.0e-26	110	COG0228	Ribosomal protein S16	87
650744389	462	56.83	6	459	1	451	0.0e+00	556	COG0541	Signal recognition particle GTPase	451
650744390	472	59.11	9	470	6	463	0.0e+00	572	COG1282	NAD/NADP transhydrogenase beta subunit	463
650744392	382	53.83	5	370	1	356	2.0e-94	339	COG3288	NAD/NADP transhydrogenase alpha subunit	356
650744393	216	42.56	22	215	6	198	1.0e-53	202	COG0740	ATP-dependent protease ClpP, protease subunit	200
650744394	303	35.57	1	295	1	289	1.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
650744396	299	28.57	87	296	18	224	9.0e-21	94.4	COG1802	DNA-binding transcriptional regulator, GntR family	230
650744398	346	31.21	4	329	1	303	4.0e-28	118	COG3547	Transposase	303
650744399	379	37.78	11	369	5	362	1.0e-92	333	COG2317	Zn-dependent carboxypeptidase, M32 family	497
650744400	238	29.8	1	232	1	240	5.0e-27	114	COG3346	Cytochrome oxidase assembly protein ShyY1	252
650744401	283	39.9	69	276	10	207	5.0e-39	155	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
650744403	317	49.03	11	317	1	299	8.0e-82	297	COG0109	Polyprenyltransferase (heme O synthase)	304
650744404	532	56.81	15	531	1	517	0.0e+00	555	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
650744405	316	29.1	45	285	17	239	3.0e-47	182	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
650744407	175	34.48	1	171	1	166	3.0e-18	84.8	COG5352	Uncharacterized protein	169
650744408	177	35.09	13	177	4	171	6.0e-29	120	COG3807	SH3-like domain	171
650744409	255	55.73	4	252	2	252	5.0e-70	257	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
650744410	246	36.96	12	235	5	211	7.0e-53	200	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
650744411	470	22.25	15	376	15	329	2.0e-15	77.7	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
650744412	784	37.19	6	782	4	730	7.0e-130	458	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
650744413	157	52.23	1	156	1	156	2.0e-44	171	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
650744414	275	37.72	4	275	2	282	1.0e-47	183	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
650744415	441	22.03	88	439	67	407	8.0e-08	52.2	COG2223	Nitrate/nitrite transporter NarK	417
650744416	454	30.82	173	453	44	328	1.0e-35	144	COG0642	Signal transduction histidine kinase	336
650744417	239	44.21	5	235	1	228	2.0e-55	209	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650744418	376	35.92	16	373	27	391	4.0e-74	272	COG0019	Diaminopimelate decarboxylase	394
650744419	240	27.23	12	239	5	234	4.0e-31	128	COG0412	Dienelactone hydrolase	236
650744421	995	28.35	360	604	3	255	2.0e-29	125	COG1216	Glycosyltransferase, GT2 family	305
650744422	889	28.52	5	881	1	739	0.0e+00	634	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
650744423	666	43.12	1	666	3	691	0.0e+00	666	COG0751	Glycyl-tRNA synthetase, beta subunit	691
650744424	301	65.29	5	295	2	291	0.0e+00	499	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
650744426	390	46.04	9	390	1	391	3.0e-96	345	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650744427	318	55.1	1	314	1	314	1.0e-115	409	COG0825	Acetyl-CoA carboxylase alpha subunit	317
650744428	287	47.02	1	285	1	280	2.0e-73	269	COG0421	Spermidine synthase	282
650744429	154	44.26	35	153	5	125	8.0e-29	119	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
650744430	252	25.95	7	230	14	272	4.0e-09	55.4	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
650744431	379	29.41	8	379	4	379	2.0e-30	127	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650744432	312	35.05	6	276	3	290	1.0e-38	154	COG0859	ADP-heptose:LPS heptosyltransferase	334
650744433	640	53.12	34	640	1	586	0.0e+00	750	COG0441	Threonyl-tRNA synthetase	589
650744435	273	40	27	269	2	244	9.0e-43	167	COG1414	DNA-binding transcriptional regulator, IclR family	246
650744436	148	21.8	6	138	3	133	1.0e-09	56.2	COG1765	Uncharacterized OsmC-related protein	137
650744437	233	48.52	1	233	1	237	1.0e-67	249	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650744438	235	40	3	235	1	250	1.0e-60	226	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650744439	302	34.74	3	297	8	311	5.0e-25	108	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
650744440	293	35.12	1	293	3	297	3.0e-37	149	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650744441	418	24.65	29	377	2	340	5.0e-26	112	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650744443	769	56.59	432	765	2	330	1.0e-118	421	COG0620	Methionine synthase II (cobalamin-independent)	330
650744444	427	22.61	38	426	5	393	2.0e-11	64.5	COG2814	Predicted arabinose efflux permease, MFS family	394
650744445	576	43.52	1	564	1	573	0.0e+00	604	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
650744446	791	37.5	19	784	3	731	0.0e+00	511	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
650744447	219	18.22	2	218	9	233	2.0e-06	46.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
650744448	328	41.72	18	327	1	312	1.0e-42	167	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650744449	327	43.43	32	324	14	307	8.0e-39	154	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650744450	509	47.15	7	497	5	494	0.0e+00	563	COG1129	ABC-type sugar transport system, ATPase component	500
650744451	344	30.77	11	344	4	322	3.0e-39	156	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650744453	196	33.33	45	166	1	126	6.0e-15	74.1	COG1695	DNA-binding transcriptional regulator, PadR family	138
650744454	91	30.95	5	88	4	87	4.0e-07	46.2	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
650744459	113	37.66	37	113	4	80	1.0e-11	61.6	COG5302	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid	80
650744461	304	31.35	5	298	2	297	5.0e-32	131	COG0583	DNA-binding transcriptional regulator, LysR family	297
650744462	253	33.86	1	252	1	251	1.0e-36	146	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650744466	320	43.09	13	315	6	315	2.0e-71	263	COG1171	Threonine dehydratase	347
650744472	459	25.12	14	429	17	387	6.0e-30	125	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
650744473	338	50.45	1	335	1	323	1.0e-105	376	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
650744474	157	44.16	1	154	2	154	1.0e-30	125	COG1522	DNA-binding transcriptional regulator, Lrp family	154
650744475	305	31.31	3	294	2	292	3.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
650744476	243	29.46	3	236	5	260	2.0e-17	82.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650744478	165	36.54	10	165	4	149	1.0e-28	119	COG5642	Uncharacterized conserved protein, DUF2384 family	149
650744480	328	41.59	18	328	1	313	7.0e-43	168	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650744481	327	43.77	32	324	14	307	6.0e-39	154	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650744482	502	47.45	1	490	6	494	0.0e+00	562	COG1129	ABC-type sugar transport system, ATPase component	500
650744483	343	30.99	1	338	7	317	8.0e-39	154	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650744484	262	43.03	12	255	1	244	1.0e-55	210	COG1414	DNA-binding transcriptional regulator, IclR family	246
650744486	623	29.61	8	531	21	598	8.0e-92	331	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
650744487	229	40.48	14	221	7	216	4.0e-28	118	COG1802	DNA-binding transcriptional regulator, GntR family	230
650744488	187	46.5	31	187	39	181	3.0e-32	131	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
650744489	409	51.75	12	409	7	404	0.0e+00	476	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
650744490	311	24.91	12	288	6	297	2.0e-13	70.1	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
650744491	910	55.43	2	903	1	822	0.0e+00	1054	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
650744493	154	42.74	24	146	2	124	1.0e-12	66.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
650744494	165	60.47	37	165	2	130	2.0e-45	175	COG0103	Ribosomal protein S9	130
650744495	158	50.34	2	148	1	147	2.0e-50	191	COG0102	Ribosomal protein L13	148
650744496	310	26.65	6	310	3	309	1.0e-30	127	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650744497	197	48.94	10	189	9	193	1.0e-44	172	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
650744498	256	27.09	4	254	9	253	1.0e-04	40.8	COG0730	Uncharacterized membrane protein YfcA	258
650744500	390	48.14	1	390	1	391	1.0e-87	317	COG0183	Acetyl-CoA acetyltransferase	392
650744501	233	58.8	1	216	1	215	4.0e-80	290	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
650744502	219	64.06	1	216	11	225	5.0e-78	284	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
650744503	426	51.73	1	425	15	444	0.0e+00	500	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
650744505	128	40.35	15	125	1	114	6.0e-17	79.5	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
650744507	284	43.62	1	282	8	285	4.0e-73	268	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
650744508	418	39.9	3	391	5	396	5.0e-109	388	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
650744509	116	57.41	1	107	3	110	5.0e-42	162	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
650744510	123	44.04	16	123	2	110	7.0e-30	122	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
650744511	121	47.62	19	121	7	111	5.0e-25	106	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
650744512	151	28.67	9	150	5	147	5.0e-22	97.4	COG0822	NifU homolog involved in Fe-S cluster formation	150
650744513	414	52.22	9	410	2	404	3.0e-124	438	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
650744514	399	31.3	20	396	21	412	2.0e-70	260	COG0719	Fe-S cluster assembly scaffold protein SufB	412
650744515	247	61.22	1	244	3	243	1.0e-98	352	COG0396	Fe-S cluster assembly ATPase SufC	251
650744516	483	45.07	40	481	1	412	1.0e-125	444	COG0719	Fe-S cluster assembly scaffold protein SufB	412
650744517	152	33.33	1	136	3	139	5.0e-24	103	COG1959	DNA-binding transcriptional regulator, IscR family	150
650744518	216	35.05	5	210	5	218	1.0e-33	136	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
650744519	437	45.73	1	431	1	457	0.0e+00	483	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
650744520	607	50.82	1	607	1	597	0.0e+00	730	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
650744522	162	21.43	22	161	33	155	5.0e-07	47.3	COG1719	Predicted hydrocarbon binding protein, contains 4VR domain	158
650744523	520	25.1	14	472	21	482	3.0e-39	156	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
650744524	95	27.37	1	95	11	101	2.0e-03	33.9	COG3293	Transposase	124
650744526	251	34.13	1	249	6	255	4.0e-48	185	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
650744527	226	49.25	13	213	1	201	3.0e-58	218	COG2039	Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)	207
650744528	286	28.82	18	286	2	282	3.0e-20	92.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650744529	644	46.04	67	621	1	525	0.0e+00	670	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
650744530	757	54.48	1	431	13	432	0.0e+00	552	COG0281	Malic enzyme	432
650744532	228	45.5	12	222	10	211	1.0e-67	249	COG0321	Lipoate-protein ligase B	221
650744533	488	20.89	1	463	2	473	4.0e-08	53.2	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
650744536	418	25.71	14	292	7	278	4.0e-26	112	COG4584	Transposase	278
650744537	264	58.46	1	259	1	260	3.0e-103	368	COG3718	5-deoxy-D-glucuronate isomerase	270
650744538	612	61.2	1	610	1	616	0.0e+00	845	COG3962	TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism	617
650744539	636	53.38	331	635	1	310	1.0e-104	374	COG3892	Myo-inositol catabolism protein IolC	310
650744541	355	31.5	28	352	2	314	6.0e-41	161	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650744542	320	29.68	21	318	18	322	6.0e-29	121	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650744543	262	58.43	1	261	5	271	8.0e-91	326	COG4130	Predicted sugar epimerase, xylose isomerase-like family	272
650744544	336	25.6	1	316	2	331	4.0e-43	168	COG0673	Predicted dehydrogenase	342
650744545	302	31	1	292	1	274	4.0e-40	158	COG1082	Sugar phosphate isomerase/epimerase	274
650744546	357	22.75	17	345	1	314	6.0e-24	105	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650744549	270	38.74	5	253	3	247	1.0e-38	153	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650744550	303	30.41	7	294	3	274	2.0e-30	126	COG1082	Sugar phosphate isomerase/epimerase	274
650744551	314	32.47	17	283	3	263	6.0e-38	151	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
650744552	263	36.82	1	254	2	254	5.0e-51	194	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
650744553	328	40.91	1	307	3	309	3.0e-68	252	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
650744554	330	37.35	1	330	3	340	2.0e-54	206	COG0673	Predicted dehydrogenase	342
650744555	373	30.75	1	373	1	341	4.0e-51	195	COG0673	Predicted dehydrogenase	342
650744556	808	32.98	26	799	53	880	0.0e+00	495	COG3002	Uncharacterized conserved protein YbcC, UPF0753/DUF2309 family	880
650744558	264	26.79	1	263	25	286	6.0e-20	91.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
650744559	338	30.67	4	325	1	303	3.0e-34	139	COG3547	Transposase	303
650744562	206	43.89	31	205	1	179	3.0e-25	108	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
650744564	178	36.03	10	145	8	137	4.0e-12	64.7	COG5612	Uncharacterized membrane protein	148
650744567	451	39.63	1	451	12	496	3.0e-83	302	COG5267	Uncharacterized conserved protein, DUF1800 family	496
650744568	408	41.81	3	407	4	418	2.0e-64	239	COG4102	Uncharacterized conserved protein, DUF1501 family	418
650744569	539	30.36	3	462	1	456	7.0e-67	248	COG0415	Deoxyribodipyrimidine photolyase	461
650744574	359	25	50	164	48	160	3.0e-06	46.2	COG3666	Transposase	161
650744578	146	17.56	11	133	8	138	2.0e-04	38.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650744581	540	43.7	1	534	3	530	0.0e+00	542	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
650744583	180	20.67	2	174	18	187	9.0e-11	60.2	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650744585	102	41.1	1	73	1	71	3.0e-09	53.5	COG5639	Uncharacterized protein	77
650744586	425	31.14	17	423	2	356	5.0e-52	198	COG2948	Type IV secretory pathway, VirB10 components	360
650744587	327	35.97	76	326	14	255	3.0e-46	179	COG3504	Type IV secretory pathway, VirB9 components	265
650744588	236	46.49	1	228	1	228	8.0e-60	223	COG3701	Type IV secretory pathway, TrbF components	228
650744589	449	30.56	7	442	32	451	4.0e-41	162	COG3846	Type IV secretory pathway, TrbL components	452
650744591	260	35.74	7	255	6	250	2.0e-30	126	COG5314	Conjugal transfer/entry exclusion protein	252
650744592	906	33.37	1	846	3	796	0.0e+00	593	COG3451	Type IV secretory pathway, VirB4 component	796
650744593	90	43.33	1	86	1	90	1.0e-17	81.2	COG5268	Type IV secretory pathway, TrbD component	93
650744594	108	46.46	11	107	12	108	1.0e-12	64.9	COG3838	Type IV secretory pathway, VirB2 components (pilins)	108
650744595	319	42.91	1	288	42	333	7.0e-79	287	COG4962	Pilus assembly protein, ATPase of CpaF family	355
650744597	671	39.22	1	579	4	579	0.0e+00	555	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
650744598	464	32.42	154	464	8	329	2.0e-38	153	COG0642	Signal transduction histidine kinase	336
650744599	241	45.69	5	234	1	229	1.0e-56	213	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650744601	419	26.72	23	400	14	386	2.0e-28	120	COG2814	Predicted arabinose efflux permease, MFS family	394
650744602	788	41.42	1	761	11	705	0.0e+00	596	COG2217	Cation transport ATPase	713
650744603	236	26.27	5	214	8	220	5.0e-05	41.8	COG0785	Cytochrome c biogenesis protein CcdA	220
650744604	71	30.99	1	71	1	71	1.0e-10	58.1	COG2608	Copper chaperone CopZ	71
650744605	156	34.86	2	109	6	113	2.0e-15	75.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
650744606	296	28.24	1	248	8	252	3.0e-22	99.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650744610	275	36.4	1	270	2	280	6.0e-59	221	COG0682	Prolipoprotein diacylglyceryltransferase	287
650744611	332	49.2	9	314	1	300	1.0e-96	346	COG0031	Cysteine synthase	300
650744612	753	50.41	4	729	4	713	0.0e+00	709	COG2217	Cation transport ATPase	713
650744613	155	31.67	1	119	1	120	2.0e-21	95.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
650744614	187	22.4	45	165	5	126	2.0e-07	49.1	COG0526	Thiol-disulfide isomerase or thioredoxin	127
650744620	309	27.31	2	215	59	269	1.0e-18	87.7	COG3336	Cytochrome c oxidase assembly factor CtaG	299
650744621	311	30.66	92	300	77	286	5.0e-15	75.3	COG1276	Putative copper export protein	289
650744622	122	32.79	1	122	5	126	4.0e-17	80	COG2372	Copper-binding protein CopC (methionine-rich)	127
650744623	537	57.48	26	536	7	517	0.0e+00	553	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
650744624	318	28.28	49	289	17	239	2.0e-43	169	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
650744625	215	37.56	1	191	1	194	1.0e-58	219	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
650744627	185	27.27	38	157	6	124	4.0e-08	51.4	COG0526	Thiol-disulfide isomerase or thioredoxin	127
650744628	186	31.4	37	156	4	122	1.0e-12	66.1	COG0526	Thiol-disulfide isomerase or thioredoxin	127
650744629	240	32.43	58	240	22	206	9.0e-37	147	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
650744631	717	30.99	307	708	170	569	2.0e-61	230	COG4232	Thiol:disulfide interchange protein	569
650744634	150	35.1	1	150	1	147	1.0e-27	115	COG3019	Uncharacterized conserved protein	149
650744635	471	29.96	11	471	1	449	3.0e-68	253	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
650744637	534	28.03	1	441	7	443	9.0e-24	105	COG0531	Amino acid transporter	466
650744640	479	41.69	19	463	6	453	8.0e-114	404	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
650744641	132	34.62	4	106	3	106	4.0e-17	80.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
650744642	681	36.39	88	402	8	320	3.0e-47	183	COG3843	Type IV secretory pathway, VirD2 components (relaxase)	326
650744644	179	39.18	3	173	2	170	8.0e-33	133	COG4959	Type IV secretory pathway, protease TraF	173
650744647	87	30.16	1	62	1	63	4.0e-03	33	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
650744650	334	40	36	329	10	298	7.0e-55	207	COG2421	Acetamidase/formamidase	305
650744651	253	39.84	3	248	1	251	4.0e-33	135	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650744654	73	25	6	65	1	60	3.0e-04	37.1	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
650744655	100	61.76	1	100	3	102	1.0e-28	117	COG5489	Uncharacterized conserved protein, DUF736 family	107
650744656	861	22.67	17	842	38	765	5.0e-61	230	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
650744657	162	28.57	1	145	5	163	1.0e-12	66	COG0723	Rieske Fe-S protein	177
650744658	117	34.48	1	87	15	99	3.0e-08	50.6	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650744659	174	31.94	5	143	2	136	2.0e-25	108	COG0394	Protein-tyrosine-phosphatase	139
650744660	140	38.46	1	117	1	117	7.0e-34	136	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
650744661	440	38.75	1	430	4	424	2.0e-79	289	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
650744662	233	30.1	32	224	1	184	2.0e-32	132	COG0431	NAD(P)H-dependent FMN reductase	184
650744665	729	24.87	11	199	2	177	5.0e-09	56.8	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
650744667	137	31.5	1	127	2	124	8.0e-09	53	COG4113	Predicted nucleic acid-binding protein, contains PIN domain	134
650744670	553	22.44	3	201	2	188	3.0e-14	73.6	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650744677	322	32.62	1	317	1	311	1.0e-47	183	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650744678	199	44.12	14	183	9	176	4.0e-46	177	COG0279	Phosphoheptose isomerase	176
650744679	261	42.21	1	259	1	251	1.0e-42	166	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650744682	277	26.57	2	141	1	124	4.0e-09	55.5	COG3293	Transposase	124
650744684	156	36.3	10	155	2	141	7.0e-29	120	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
650744685	550	37.18	9	548	2	529	8.0e-127	448	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650744686	392	26.29	40	381	34	383	5.0e-08	52.5	COG2814	Predicted arabinose efflux permease, MFS family	394
650744687	329	30.93	5	329	1	326	5.0e-49	188	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
650744688	595	53.58	4	587	1	583	0.0e+00	824	COG0173	Aspartyl-tRNA synthetase	585
650744689	392	42.03	13	375	1	361	1.0e-88	320	COG0349	Ribonuclease D	361
650744690	257	33.2	5	252	13	262	5.0e-22	98.3	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
650744691	282	29.69	18	246	17	242	9.0e-17	80.9	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
650744692	271	35.88	5	258	4	254	2.0e-57	216	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
650744693	306	23.79	33	271	42	278	1.0e-29	124	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
650744694	76	42.31	1	51	1	52	4.0e-07	46.5	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
650744696	424	63.01	7	424	8	422	0.0e+00	483	COG2379	Glycerate-2-kinase	422
650744699	329	46.06	1	328	2	316	3.0e-91	328	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
650744700	325	46.77	5	311	23	332	2.0e-99	356	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
650744701	149	61.81	6	149	3	146	2.0e-58	218	COG0757	3-dehydroquinate dehydratase	146
650744702	160	39.07	10	160	1	139	5.0e-23	100	COG0511	Biotin carboxyl carrier protein	140
650744706	763	23.23	17	758	10	759	2.0e-93	337	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
650744708	238	38.94	1	224	5	223	8.0e-37	147	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
650744709	499	58.6	1	499	3	498	0.0e+00	720	COG0554	Glycerol kinase	499
650744710	505	49.61	1	504	11	514	0.0e+00	510	COG0578	Glycerol-3-phosphate dehydrogenase	532
650744711	268	46.53	12	256	6	250	3.0e-66	245	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
650744713	505	37.89	186	482	87	408	5.0e-42	165	COG0840	Methyl-accepting chemotaxis protein	408
650744714	291	33.64	45	255	1	200	1.0e-27	116	COG0625	Glutathione S-transferase	211
650744715	466	37.61	10	466	18	471	3.0e-101	362	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650744716	479	45.26	7	478	1	469	5.0e-121	428	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650744717	516	21.77	39	498	20	464	1.0e-24	108	COG0531	Amino acid transporter	466
650744718	347	32.67	234	333	27	127	3.0e-12	66	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
650744719	493	34.71	49	492	1	443	3.0e-96	346	COG0174	Glutamine synthetase	443
650744720	389	41.27	7	380	3	377	2.0e-96	346	COG1454	Alcohol dehydrogenase, class IV	377
650744722	1139	47.91	5	1136	3	1138	0.0e+00	1170	COG0587	DNA polymerase III, alpha subunit	1139
650744723	389	30.08	1	388	1	392	1.0e-62	234	COG0183	Acetyl-CoA acetyltransferase	392
650744724	249	32.24	3	245	6	246	2.0e-34	139	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
650744725	329	23.71	1	323	1	309	2.0e-31	129	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650744726	131	33.07	1	125	6	131	5.0e-18	83.3	COG1917	Cupin domain protein related to quercetin dioxygenase	131
650744728	492	35.03	1	459	1	467	2.0e-88	319	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
650744729	292	37.74	32	284	1	240	3.0e-34	139	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
650744730	263	41.18	3	255	2	253	4.0e-59	221	COG1192	Cellulose biosynthesis protein BcsQ	259
650744731	217	41.86	20	188	12	181	8.0e-40	157	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
650744732	566	50.57	2	562	9	618	0.0e+00	747	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
650744733	433	40.89	7	433	5	454	4.0e-113	401	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
650744734	116	41.07	55	110	3	58	4.0e-11	59.9	COG3411	(2Fe-2S) ferredoxin	64
650744735	684	42.54	8	681	8	667	0.0e+00	612	COG1331	Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains	667
650744736	360	40.78	40	316	2	265	2.0e-52	200	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
650744737	155	31.29	1	143	1	141	4.0e-22	97.3	COG2927	DNA polymerase III, chi subunit	144
650744739	390	50.74	1	390	1	403	1.0e-116	413	COG2081	Predicted flavoprotein YhiN	408
650744740	309	37.33	4	300	1	296	5.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
650744741	362	24.38	21	330	10	319	1.0e-26	114	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
650744743	346	17.56	24	297	4	279	9.0e-08	51.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
650744746	424	44.69	3	412	1	409	3.0e-87	315	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
650744747	257	57.65	1	253	1	255	6.0e-93	334	COG3622	Hydroxypyruvate isomerase	260
650744748	303	43.66	10	292	4	286	9.0e-64	237	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
650744749	365	35.33	35	365	1	329	6.0e-67	248	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
650744750	302	34.97	9	293	2	286	2.0e-63	236	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
650744751	211	39.23	1	204	3	206	2.0e-42	165	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
650744752	192	26.88	1	90	1	93	5.0e-08	51.1	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
650744754	494	21.45	17	416	20	359	2.0e-14	74.5	COG2814	Predicted arabinose efflux permease, MFS family	394
650744755	1139	30.44	17	685	2	640	0.0e+00	519	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
650744756	354	36.05	13	351	10	351	1.0e-35	143	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
650744757	300	34.32	6	300	1	294	9.0e-37	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
650744758	345	54.87	32	338	5	304	3.0e-95	342	COG0492	Thioredoxin reductase	305
650744759	168	40.79	18	168	4	154	8.0e-29	119	COG1522	DNA-binding transcriptional regulator, Lrp family	154
650744760	287	23.67	18	254	17	259	3.0e-13	69.6	COG3336	Cytochrome c oxidase assembly factor CtaG	299
650744761	772	37.01	14	772	8	766	0.0e+00	584	COG4775	Outer membrane protein assembly factor BamA	766
650744762	259	19.59	94	237	24	169	1.0e-07	50.3	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
650744763	361	48.47	18	342	1	326	1.0e-87	316	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
650744764	165	46.58	17	160	3	146	3.0e-43	167	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
650744765	268	53.94	2	255	6	259	5.0e-93	334	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
650744766	287	47.64	7	276	5	278	1.0e-58	220	COG3494	Uncharacterized conserved protein, DUF1009 family	279
650744767	130	21.43	5	128	2	138	5.0e-11	60.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
650744774	170	26.32	8	152	4	155	3.0e-11	61.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650744775	559	46.61	5	541	1	530	0.0e+00	571	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
650744777	323	33.75	4	320	3	302	1.0e-58	220	COG1893	Ketopantoate reductase	307
650744778	506	37.09	4	502	12	525	2.0e-97	350	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
650744779	374	23.58	1	371	1	384	3.0e-44	172	COG1252	NADH dehydrogenase, FAD-containing subunit	405
650744780	68	41.18	1	67	3	70	1.0e-07	48.5	COG2608	Copper chaperone CopZ	71
650744781	745	50.75	19	743	4	713	0.0e+00	678	COG2217	Cation transport ATPase	713
650744782	247	38.34	4	245	2	251	3.0e-41	161	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650744783	308	27.24	8	292	6	286	7.0e-31	128	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
650744784	332	37.15	4	315	2	324	8.0e-77	280	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
650744785	567	42.75	23	562	28	574	0.0e+00	547	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
650744786	240	29.49	7	223	3	205	2.0e-27	116	COG0684	Regulator of RNase E activity RraA	210
650744788	149	46.94	4	149	2	148	2.0e-38	151	COG1981	Uncharacterized membrane protein	149
650744789	230	31.53	5	225	2	218	1.0e-30	126	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
650744790	362	35.8	11	331	5	320	1.0e-84	306	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
650744791	358	46.15	1	347	1	350	2.0e-91	329	COG0407	Uroporphyrinogen-III decarboxylase	352
650744792	288	44.07	8	274	6	266	5.0e-75	274	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
650744794	325	45.87	4	325	2	326	8.0e-71	260	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
650744797	143	29.37	19	143	4	119	3.0e-15	74.5	COG1539	Dihydroneopterin aldolase	121
650744798	418	30.62	1	416	2	408	4.0e-45	175	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
650744799	450	37.43	76	447	6	377	2.0e-71	263	COG0015	Adenylosuccinate lyase	438
650744800	464	31.01	15	458	11	432	3.0e-54	206	COG1457	Purine-cytosine permease or related protein	442
650744808	174	55.17	1	174	1	171	2.0e-53	201	COG0221	Inorganic pyrophosphatase	171
650744809	286	21.77	5	240	4	273	2.0e-10	59.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
650744810	218	31.31	13	207	12	208	4.0e-22	98.4	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
650744812	106	36.49	1	74	1	74	3.0e-09	53.4	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
650744813	185	35.45	10	185	5	191	5.0e-27	113	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
650744814	381	38.63	24	380	30	392	3.0e-72	266	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
650744816	312	52.41	3	305	30	340	4.0e-94	338	COG0552	Signal recognition particle GTPase	340
650744817	411	39.49	1	408	3	433	9.0e-117	413	COG0621	tRNA A37 methylthiotransferase MiaB	437
650744818	277	44.12	6	271	2	271	1.0e-81	296	COG0253	Diaminopimelate epimerase	272
650744819	489	21.11	38	465	36	448	3.0e-14	74	COG0531	Amino acid transporter	466
650744820	240	54.19	23	225	1	203	3.0e-73	268	COG0177	Endonuclease III	211
650744821	181	32.24	21	171	13	164	1.0e-22	99.6	COG5488	Uncharacterized membrane protein	164
650744822	382	47.12	1	380	11	391	2.0e-61	229	COG2814	Predicted arabinose efflux permease, MFS family	394
650744823	549	49.09	1	534	1	523	0.0e+00	514	COG0459	Chaperonin GroEL (HSP60 family)	524
650744824	104	69.47	1	95	1	95	3.0e-34	136	COG0234	Co-chaperonin GroES (HSP10)	96
650744825	108	59.21	26	101	7	82	1.0e-24	104	COG5425	Usg protein (tryptophan operon, function unknown)	90
650744827	461	20.41	30	269	39	282	2.0e-35	144	COG5410	Uncharacterized protein	305
650744845	374	22.8	13	371	15	348	7.0e-11	61.9	COG3299	Uncharacterized phage protein gp47/JayE	353
650744857	727	52.14	12	706	1	696	0.0e+00	857	COG0855	Polyphosphate kinase	696
650744859	364	30.47	1	361	3	355	1.0e-34	140	COG0628	Predicted PurR-regulated permease PerM	355
650744860	356	59.41	11	348	5	343	5.0e-127	447	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
650744861	206	52.02	4	201	2	198	1.0e-66	246	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
650744864	313	51.78	10	311	2	310	5.0e-112	397	COG0078	Ornithine carbamoyltransferase	310
650744865	393	50.13	1	382	18	398	0.0e+00	462	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
650744866	501	29.25	12	461	1	459	6.0e-67	248	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
650744867	176	25.19	21	148	41	160	4.0e-08	51.5	COG4731	Uncharacterized conserved protein, DUF2147 family	162
650744868	331	25.25	35	318	30	324	2.0e-23	103	COG3528	Uncharacterized protein	330
650744869	118	55.88	17	118	6	107	1.0e-34	138	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
650744870	775	48.21	1	753	1	786	0.0e+00	870	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
650744872	436	29.74	18	426	4	387	2.0e-68	253	COG0247	Fe-S oxidoreductase	388
650744873	392	27.4	2	389	36	455	5.0e-37	148	COG0277	FAD/FMN-containing dehydrogenase	459
650744874	486	42.73	22	472	2	459	3.0e-90	326	COG0277	FAD/FMN-containing dehydrogenase	459
650744877	301	33.8	3	284	2	284	4.0e-56	211	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
650744878	246	60.85	11	244	4	238	6.0e-87	313	COG0528	Uridylate kinase	238
650744879	188	52.69	3	188	2	187	3.0e-58	218	COG0233	Ribosome recycling factor	187
650744880	254	53.68	9	239	13	243	3.0e-81	294	COG0020	Undecaprenyl pyrophosphate synthase	245
650744881	231	35.65	17	213	39	254	2.0e-26	112	COG0575	CDP-diglyceride synthetase	265
650744882	391	53.11	3	386	1	384	4.0e-127	448	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
650744883	353	40.27	4	353	1	375	1.0e-53	203	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
650744884	339	65.28	1	337	3	338	0.0e+00	539	COG0059	Ketol-acid reductoisomerase	338
650744885	310	60.93	3	302	1	300	2.0e-113	401	COG0031	Cysteine synthase	300
650744886	209	31.94	13	200	12	202	3.0e-28	118	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
650744888	280	32.8	9	256	1	243	2.0e-45	176	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
650744889	423	27.52	8	417	3	445	1.0e-55	210	COG1070	Sugar (pentulose or hexulose) kinase	502
650744890	336	42.39	11	316	10	316	1.0e-71	263	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
650744891	478	19.87	19	474	1	431	3.0e-29	123	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650744892	308	34.8	12	305	1	295	1.0e-50	193	COG1175	ABC-type sugar transport system, permease component	295
650744893	285	36.4	6	284	8	281	1.0e-47	183	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650744894	362	40.92	1	346	1	338	9.0e-88	317	COG3839	ABC-type sugar transport system, ATPase component	338
650744895	365	41.69	1	354	2	338	3.0e-91	328	COG3839	ABC-type sugar transport system, ATPase component	338
650744896	520	30.64	1	511	1	502	8.0e-78	284	COG1070	Sugar (pentulose or hexulose) kinase	502
650744897	349	42.31	38	349	8	315	4.0e-76	278	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
650744898	222	32.88	1	214	3	219	1.0e-41	163	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
650744899	495	50.82	1	482	9	492	0.0e+00	532	COG0578	Glycerol-3-phosphate dehydrogenase	532
650744900	330	27.34	7	325	12	404	2.0e-46	179	COG3347	Rhamnose utilisation protein RhaD, predicted bifunctional aldolase and dehydrogenase	404
650744901	201	42.19	8	198	9	200	1.0e-33	136	COG2860	Uncharacterized membrane protein YeiH	209
650744902	399	43.65	18	399	6	393	5.0e-77	282	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
650744903	382	44.65	2	376	4	384	2.0e-90	326	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650744904	285	42.2	5	285	1	273	2.0e-67	249	COG3777	Hydroxyacyl-ACP dehydratase HTD2, hotdog domain	273
650744905	289	29.58	144	278	1	142	6.0e-15	75.1	COG2030	Acyl dehydratase	159
650744907	309	38.58	9	254	2	246	3.0e-33	135	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650744910	251	28.79	35	229	3	189	2.0e-27	115	COG3271	Predicted double-glycine peptidase	201
650744915	642	36.03	213	592	1	408	4.0e-59	222	COG0840	Methyl-accepting chemotaxis protein	408
650744916	315	37.42	17	315	2	291	6.0e-61	227	COG3386	Sugar lactone lactonase YvrE	307
650744917	316	38.17	1	316	1	312	1.0e-39	156	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650744918	332	36.72	31	331	12	316	3.0e-40	159	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650744919	493	48.39	1	483	4	500	0.0e+00	508	COG1129	ABC-type sugar transport system, ATPase component	500
650744920	376	27.56	21	326	5	313	1.0e-33	137	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650744921	304	35.89	7	290	2	277	1.0e-57	217	COG3386	Sugar lactone lactonase YvrE	307
650744922	206	32.86	1	206	3	211	2.0e-41	161	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
650744923	296	43.97	2	275	8	287	8.0e-54	204	COG3734	2-keto-3-deoxy-galactonokinase	306
650744924	257	29.37	11	256	2	250	2.0e-40	159	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650744926	324	37.7	12	320	3	314	4.0e-41	162	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650744927	363	26.54	19	339	4	316	6.0e-34	138	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650744928	272	43.87	13	261	2	251	1.0e-39	156	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650744930	346	30.7	1	329	2	313	2.0e-41	163	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650744931	360	37.89	39	359	4	313	1.0e-54	207	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650744933	345	47.19	48	313	1	265	2.0e-87	315	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
650744934	95	56.19	1	95	5	109	2.0e-26	110	COG3460	1,2-phenylacetyl-CoA epoxidase, PaaB subunit	117
650744935	258	42.57	13	258	20	265	1.0e-55	209	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
650744936	164	35.58	4	104	9	111	6.0e-17	80.3	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
650744937	364	28.91	8	300	1	266	6.0e-43	168	COG1018	Ferredoxin-NADP reductase	266
650744940	386	24.93	17	369	2	323	2.0e-27	116	COG1275	Tellurite resistance protein TehA and related permeases	329
650744941	333	49.39	1	327	1	322	4.0e-90	324	COG2376	Dihydroxyacetone kinase	323
650744943	748	39.03	250	748	6	543	1.0e-100	361	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
650744945	510	56.08	15	491	1	485	0.0e+00	549	COG0606	Predicted ATPase with chaperone activity	490
650744946	266	40.55	45	261	8	224	1.0e-57	217	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
650744947	116	36.7	14	116	20	128	1.0e-21	95	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
650744950	272	46.33	16	272	1	256	6.0e-72	264	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
650744951	427	19.86	8	287	4	278	8.0e-12	65.5	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
650744952	746	23.63	10	742	15	764	3.0e-69	256	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
650744953	376	27.96	10	376	1	364	3.0e-38	152	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
650744954	374	25.62	10	367	4	364	2.0e-35	143	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
650744955	241	59.26	4	237	1	243	4.0e-79	287	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
650744956	325	50.3	3	325	1	329	5.0e-95	341	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
650744957	209	31.61	12	185	6	166	6.0e-30	124	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
650744958	153	36.69	1	135	8	145	2.0e-28	118	COG0071	Molecular chaperone IbpA, HSP20 family	146
650744959	75	45.45	1	75	1	75	3.0e-20	90.3	COG0254	Ribosomal protein L31	75
650744961	209	36.54	8	203	71	277	3.0e-38	151	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
650744965	470	49.6	1	368	28	397	9.0e-116	410	COG0513	Superfamily II DNA and RNA helicase	513
650744966	616	39.61	13	609	11	601	4.0e-109	388	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
650744967	347	37.78	1	347	4	337	7.0e-71	261	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
650744968	338	28.12	32	322	1	291	2.0e-32	133	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
650744969	256	29.76	1	83	9	90	2.0e-09	56.4	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
650744970	312	20.9	1	309	1	281	8.0e-22	98	COG3302	DMSO reductase anchor subunit	281
650744971	247	41.67	5	219	2	199	3.0e-50	191	COG0437	Fe-S-cluster-containing dehydrogenase component	203
650744972	935	24.53	18	912	42	765	4.0e-90	326	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
650744973	478	26.73	47	469	29	447	8.0e-54	205	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
650744974	1049	43.06	1	1028	1	1009	0.0e+00	861	COG0841	Multidrug efflux pump subunit AcrB	1009
650744975	386	27.68	1	380	7	371	1.0e-23	104	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
650744976	528	50.32	1	309	3	313	7.0e-96	345	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
650744977	396	30.49	13	384	1	360	2.0e-88	319	COG1932	Phosphoserine aminotransferase	365
650744978	247	44.72	2	247	1	245	2.0e-78	285	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
650744979	110	31.63	11	107	1	98	2.0e-06	44.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
650744980	418	37.85	95	417	2	352	8.0e-59	221	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
650744982	101	34.38	5	98	1	96	2.0e-05	40.6	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
650744983	279	57.5	4	279	1	280	3.0e-104	371	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
650744986	327	42.45	1	314	1	315	2.0e-75	276	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650744987	212	54.82	10	205	1	195	8.0e-71	259	COG0302	GTP cyclohydrolase I	195
650744988	142	52.1	19	137	7	124	5.0e-39	153	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
650744990	292	38.41	14	282	7	280	2.0e-63	236	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
650744991	231	52	1	224	3	226	9.0e-78	283	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
650744992	727	50.27	4	720	12	743	0.0e+00	866	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
650744993	77	36.47	1	77	1	85	3.0e-17	80	COG0271	Stress-induced morphogen (activity unknown)	90
650744994	115	63.37	6	105	1	101	1.0e-40	158	COG0278	Glutaredoxin-related protein	105
650744996	1147	62.71	2	1146	5	1147	0.0e+00	1756	COG1038	Pyruvate carboxylase	1149
650744997	556	22.11	41	534	7	450	4.0e-20	93.5	COG1231	Monoamine oxidase	450
650744998	217	33.8	1	216	2	203	2.0e-24	106	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
650745004	444	38.36	1	442	9	469	2.0e-102	366	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
650745005	396	22.95	42	392	37	384	5.0e-13	69.1	COG2814	Predicted arabinose efflux permease, MFS family	394
650745006	149	41.38	31	145	5	120	2.0e-24	105	COG1321	Mn-dependent transcriptional regulator, DtxR family	154
650745008	352	27.25	18	342	9	341	5.0e-30	125	COG0628	Predicted PurR-regulated permease PerM	355
650745009	91	40.7	1	85	3	88	8.0e-22	95.3	COG1254	Acylphosphatase	92
650745010	233	42.48	2	226	34	257	1.0e-44	173	COG5387	Chaperone required for the assembly of the mitochondrial F1-ATPase	264
650745013	339	29.88	35	339	5	328	5.0e-42	165	COG3660	Mitochondrial fission protein ELM1	329
650745014	320	22.34	46	307	48	317	3.0e-06	46.1	COG3608	Predicted deacylase	331
650745015	292	34.88	19	274	1	231	4.0e-38	151	COG1183	Phosphatidylserine synthase	234
650745016	229	43.32	4	216	18	233	1.0e-49	190	COG0688	Phosphatidylserine decarboxylase	239
650745017	361	20.7	47	329	25	263	2.0e-06	47.6	COG1652	Nucleoid-associated protein YgaU, contains BON and LysM domains	269
650745018	194	41.08	1	181	12	195	3.0e-37	148	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
650745021	188	50.26	1	188	2	191	1.0e-52	199	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
650745022	72	66.67	1	72	1	72	4.0e-23	99.5	COG0361	Translation initiation factor IF-1	75
650745023	436	55.35	2	429	1	423	0.0e+00	490	COG0141	Histidinol dehydrogenase	425
650745024	231	42.66	18	231	3	216	3.0e-50	191	COG0040	ATP phosphoribosyltransferase	290
650745025	342	24.84	39	338	1	305	3.0e-42	165	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
650745026	392	44.42	2	391	4	396	1.0e-99	357	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
650745027	290	50.53	2	285	1	285	7.0e-83	300	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
650745030	394	51.7	41	390	1	343	2.0e-121	428	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
650745031	235	33.86	1	228	3	251	1.0e-31	130	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650745032	100	52.11	1	71	1	71	2.0e-16	77.6	COG0227	Ribosomal protein L28	77
650745033	167	43.98	2	167	1	166	4.0e-42	163	COG5465	Uncharacterized protein	166
650745034	270	40.38	8	269	3	265	1.0e-48	186	COG0345	Pyrroline-5-carboxylate reductase	266
650745035	509	34.56	73	447	1	408	4.0e-53	202	COG0840	Methyl-accepting chemotaxis protein	408
650745036	100	23.86	3	86	9	96	1.0e-03	34.6	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
650745038	712	40.55	1	699	3	716	0.0e+00	608	COG0643	Chemotaxis protein histidine kinase CheA	716
650745039	154	40.14	8	154	14	160	1.0e-33	135	COG0835	Chemotaxis signal transduction protein	165
650745040	298	44.69	24	293	1	268	1.0e-72	266	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
650745041	350	55.68	2	348	1	349	4.0e-104	371	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
650745043	189	43.04	9	164	4	161	3.0e-42	165	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
650745045	95	25	3	82	1	80	2.0e-04	37.2	COG0236	Acyl carrier protein	80
650745047	278	28.63	23	219	11	234	4.0e-13	69.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
650745048	296	40.14	4	278	65	334	5.0e-66	244	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
650745049	332	47.37	14	315	4	288	6.0e-83	301	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
650745051	60	58.14	3	45	7	49	3.0e-07	47	COG4338	Uncharacterized protein	54
650745053	468	21.12	11	465	7	411	3.0e-24	106	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
650745055	434	18.97	53	418	48	383	6.0e-08	52.5	COG2814	Predicted arabinose efflux permease, MFS family	394
650745057	588	38.18	6	440	7	467	2.0e-84	307	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
650745059	210	42.72	11	210	48	249	1.0e-51	195	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
650745060	260	25.54	1	213	1	229	2.0e-28	119	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
650745061	267	42.29	8	260	3	236	2.0e-64	239	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
650745062	272	30.53	8	269	3	257	1.0e-32	133	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
650745063	359	23.36	3	317	1	311	1.0e-20	94.1	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
650745065	437	32	22	437	13	397	2.0e-74	273	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
650745066	1034	32.5	2	1029	1	1025	0.0e+00	589	COG3696	Cu/Ag efflux pump CusA	1027
650745068	467	25.44	28	457	1	442	5.0e-14	72.9	COG1538	Outer membrane protein TolC	457
650745069	309	32.88	9	300	4	292	2.0e-38	153	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
650745070	264	38.75	19	256	14	253	2.0e-49	189	COG4705	Uncharacterized membrane-anchored protein	258
650745071	283	46.34	38	283	6	244	6.0e-66	244	COG0020	Undecaprenyl pyrophosphate synthase	245
650745075	276	26.18	4	263	1	275	2.0e-22	99.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650745076	242	39.01	11	232	4	219	1.0e-40	160	COG0765	ABC-type amino acid transport system, permease component	222
650745077	264	55.65	26	264	3	240	9.0e-95	340	COG1126	ABC-type polar amino acid transport system, ATPase component	240
650745078	461	32.95	11	439	8	438	1.0e-79	290	COG0015	Adenylosuccinate lyase	438
650745079	162	23.12	6	143	18	175	5.0e-18	83.8	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
650745080	117	31.03	7	116	9	123	2.0e-16	77.7	COG0073	tRNA-binding EMAP/Myf domain	123
650745081	536	38.78	11	536	11	539	2.0e-130	460	COG0405	Gamma-glutamyltranspeptidase	539
650745083	661	36.07	10	655	7	687	0.0e+00	484	COG0480	Translation elongation factor EF-G, a GTPase	697
650745084	261	39.83	21	260	14	254	4.0e-39	155	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
650745085	240	42.8	1	237	4	250	8.0e-43	167	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650745086	234	30.67	61	207	37	186	7.0e-19	87.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650745087	156	25.17	5	147	6	136	1.0e-16	79.2	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
650745088	118	36.79	1	103	2	105	6.0e-18	82.7	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
650745089	211	34.51	1	211	2	212	3.0e-40	158	COG0602	Organic radical activating enzyme	212
650745091	405	49.75	1	401	1	404	0.0e+00	464	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
650745092	215	39.3	1	198	2	199	7.0e-39	153	COG0237	Dephospho-CoA kinase	201
650745093	276	43.82	3	276	2	283	6.0e-67	247	COG0169	Shikimate 5-dehydrogenase	283
650745094	233	25.64	9	187	7	193	4.0e-08	51.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
650745096	156	38.61	1	156	6	161	6.0e-23	100	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
650745097	283	56.54	1	282	6	287	2.0e-113	401	COG0788	Formyltetrahydrofolate hydrolase	287
650745098	235	38.12	3	220	14	234	3.0e-40	158	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
650745099	696	48.7	6	694	1	680	0.0e+00	800	COG1770	Protease II	682
650745100	557	63.06	3	557	1	554	0.0e+00	810	COG2759	Formyltetrahydrofolate synthetase	554
650745102	304	39.07	11	303	5	305	9.0e-58	217	COG0010	Arginase family enzyme	305
650745104	453	38.58	10	452	8	468	2.0e-81	296	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
650745105	391	60.89	11	391	7	379	0.0e+00	476	COG3970	Fumarylacetoacetate (FAA) hydrolase family protein	379
650745106	210	46.27	4	203	1	201	7.0e-41	160	COG1279	Arginine exporter protein ArgO	202
650745107	295	28.9	2	294	1	296	6.0e-18	85	COG0583	DNA-binding transcriptional regulator, LysR family	297
650745108	284	41.2	22	283	14	280	4.0e-42	165	COG5473	Uncharacterized membrane protein	290
650745109	296	32.4	12	296	2	313	2.0e-53	202	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650745110	289	30.69	1	287	10	290	1.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
650745111	314	52.63	9	309	3	298	6.0e-90	324	COG3246	Uncharacterized conserved protein, DUF849 family	298
650745112	312	34.89	1	234	4	234	5.0e-50	191	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
650745113	362	28.25	13	322	9	317	6.0e-32	131	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650745114	519	41.47	27	508	2	500	3.0e-125	442	COG1129	ABC-type sugar transport system, ATPase component	500
650745115	320	29.13	15	318	4	310	1.0e-32	133	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650745116	312	34.2	1	306	1	305	6.0e-35	141	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650745118	429	57.21	1	428	1	430	0.0e+00	595	COG0104	Adenylosuccinate synthase	430
650745119	378	28.57	11	362	4	376	4.0e-33	135	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
650745120	487	37.18	4	381	4	384	2.0e-63	237	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
650745122	186	29.61	1	145	1	150	3.0e-16	78.5	COG3613	Nucleoside 2-deoxyribosyltransferase	172
650745123	668	37.03	33	663	29	604	3.0e-129	456	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
650745124	615	26.94	2	608	100	772	8.0e-108	385	COG4993	Glucose dehydrogenase	773
650745125	285	18.8	1	256	1	247	2.0e-13	70	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
650745126	249	40.59	22	122	9	109	4.0e-18	85.2	COG4654	Cytochrome c551/c552	110
650745127	190	27.61	27	160	8	133	2.0e-14	72.7	COG3791	Uncharacterized conserved protein	133
650745128	369	67.21	1	369	1	366	0.0e+00	565	COG1062	Zn-dependent alcohol dehydrogenase	366
650745129	701	21.74	1	699	10	768	3.0e-32	134	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
650745130	468	40.86	8	468	2	456	5.0e-82	298	COG0277	FAD/FMN-containing dehydrogenase	459
650745131	552	23.32	6	511	110	680	7.0e-56	212	COG4993	Glucose dehydrogenase	773
650745133	557	41.32	12	557	9	503	6.0e-127	448	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
650745134	227	38.64	9	220	24	242	2.0e-43	169	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
650745135	582	40.7	29	582	13	587	0.0e+00	468	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
650745136	263	49.59	7	245	1	238	2.0e-60	225	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
650745137	186	29.78	1	175	3	178	5.0e-14	70.7	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
650745138	169	39.19	22	168	6	152	2.0e-32	131	COG1522	DNA-binding transcriptional regulator, Lrp family	154
650745139	179	47.06	6	173	1	169	3.0e-48	184	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
650745140	266	39.53	8	263	17	268	4.0e-52	198	COG3752	Steroid 5-alpha reductase family enzyme	272
650745141	341	28.62	45	337	1	283	3.0e-65	242	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
650745146	230	30.94	1	218	19	239	2.0e-44	172	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
650745147	123	29	1	100	2	99	9.0e-10	55.6	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650745148	140	43.1	1	116	1	116	3.0e-37	147	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
650745149	439	39.53	1	429	4	424	6.0e-79	288	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
650745154	221	25	6	206	4	211	1.0e-15	76.7	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650745156	240	39.66	10	235	3	228	4.0e-47	181	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650745157	384	57.59	193	383	5	193	6.0e-60	225	COG0807	GTP cyclohydrolase II	193
650745160	112	22.47	2	90	27	112	4.0e-07	46.8	COG2919	Cell division protein FtsB	117
650745161	345	49.85	23	345	20	345	1.0e-112	400	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
650745162	455	55.14	134	454	1	321	0.0e+00	481	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
650745163	428	46.28	1	428	1	403	3.0e-101	362	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
650745164	169	28.26	15	147	3	137	4.0e-09	54.5	COG1247	L-amino acid N-acyltransferase YncA	169
650745165	465	47.15	2	454	1	453	0.0e+00	481	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
650745166	320	61.41	16	313	9	306	0.0e+00	470	COG0320	Lipoate synthase	306
650745167	156	45.14	1	142	1	144	1.0e-43	168	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
650745168	352	41	15	348	1	337	5.0e-71	261	COG2008	Threonine aldolase	342
650745169	363	41.52	12	343	28	364	1.0e-75	277	COG1858	Cytochrome c peroxidase	364
650745171	194	34.05	7	187	1	181	2.0e-26	112	COG0431	NAD(P)H-dependent FMN reductase	184
650745172	341	33.65	11	327	5	309	3.0e-64	239	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
650745173	303	37.29	1	292	1	291	9.0e-35	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
650745175	172	51.52	8	172	1	163	6.0e-44	170	COG0440	Acetolactate synthase, small subunit	163
650745176	593	49.56	10	572	3	549	0.0e+00	627	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
650745177	325	42.61	13	292	2	285	2.0e-68	252	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
650745178	290	49.05	74	282	3	212	4.0e-47	182	COG0560	Phosphoserine phosphatase	212
650745179	141	50	3	139	1	138	5.0e-41	160	COG1832	Predicted CoA-binding protein	140
650745180	529	28.91	12	297	16	305	1.0e-44	174	COG5309	Exo-beta-1,3-glucanase,  GH17 family	305
650745182	177	24.79	56	176	37	157	8.0e-06	43.5	COG5490	Uncharacterized protein	158
650745183	106	41.67	11	106	12	107	8.0e-26	108	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
650745184	155	26.62	1	140	6	159	2.0e-13	68.1	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
650745185	68	64.71	1	68	1	67	2.0e-22	97.5	COG1278	Cold shock protein, CspA family	67
650745187	411	44.6	37	379	3	354	1.0e-70	260	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
650745188	308	27	40	275	20	239	2.0e-20	93.2	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
650745189	333	25.5	42	322	10	307	5.0e-16	78.7	COG3391	DNA-binding beta-propeller fold protein YncE	381
650745192	254	31.44	9	254	19	281	4.0e-16	78.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650745193	137	45.03	1	135	2	152	2.0e-39	154	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
650745194	97	34.07	1	89	1	91	1.0e-15	74.9	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
650745195	270	37.55	25	268	34	278	2.0e-36	145	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
650745197	173	41.1	1	146	1	143	7.0e-34	136	COG2332	Cytochrome c-type biogenesis protein CcmE	153
650745198	657	47.38	1	644	1	646	0.0e+00	520	COG1138	Cytochrome c biogenesis factor	648
650745199	184	22.22	42	163	5	127	4.0e-09	54.5	COG0526	Thiol-disulfide isomerase or thioredoxin	127
650745200	163	38.78	18	163	10	151	4.0e-31	127	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
650745201	258	31.56	1	236	2	241	2.0e-14	73.4	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
650745202	606	29.34	47	469	25	443	2.0e-61	230	COG0038	H+/Cl- antiporter ClcA	443
650745203	508	26.31	1	508	2	530	1.0e-68	254	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
650745205	203	29.93	53	199	43	186	7.0e-17	80.7	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
650745206	809	35.73	1	806	46	840	0.0e+00	568	COG1643	HrpA-like RNA helicase	845
650745207	675	29.61	237	675	129	569	1.0e-68	254	COG4232	Thiol:disulfide interchange protein	569
650745210	413	23.38	54	395	13	356	9.0e-20	91.7	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650745211	333	44.55	7	332	1	326	2.0e-81	296	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
650745213	261	48.21	8	258	6	256	6.0e-82	297	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
650745214	260	47.04	7	259	11	263	2.0e-56	213	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
650745215	357	42.33	5	353	6	357	2.0e-94	339	COG0787	Alanine racemase	360
650745217	494	42.35	14	490	1	434	9.0e-121	427	COG0305	Replicative DNA helicase	435
650745219	147	55.07	5	141	4	141	4.0e-35	140	COG5579	Uncharacterized protein, DUF1810 family	143
650745220	143	42.96	1	142	1	142	4.0e-36	143	COG4154	L-fucose mutarotase/ribose pyranase, RbsD/FucU family	144
650745221	300	41.75	2	298	3	309	9.0e-45	174	COG0524	Sugar or nucleoside kinase, ribokinase family	311
650745222	439	52.18	29	437	1	400	4.0e-111	395	COG0004	Ammonia channel protein AmtB	409
650745225	298	42.7	19	282	2	267	3.0e-60	225	COG2240	Pyridoxal/pyridoxine/pyridoxamine kinase	281
650745226	360	43.14	2	348	1	338	1.0e-93	336	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
650745227	231	37.93	1	231	3	200	4.0e-47	181	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
650745228	256	25.29	81	251	2	174	5.0e-14	71.9	COG1076	DnaJ-domain-containing proteins 1	174
650745229	220	43.67	2	213	26	254	2.0e-58	218	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
650745231	812	60	24	582	6	556	0.0e+00	872	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
650745232	299	38.83	2	272	1	267	3.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
650745233	313	30.32	3	311	1	306	5.0e-31	128	COG0679	Predicted permease	311
650745234	1069	35.57	805	1056	6	256	1.0e-48	188	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
650745238	131	23.08	4	107	2	105	1.0e-06	45.8	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
650745239	182	30.05	2	179	1	180	2.0e-20	91.9	COG2840	DNA-nicking endonuclease, Smr domain	184
650745240	234	26.29	9	227	4	218	9.0e-22	97.3	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
650745241	473	45.24	7	466	6	459	0.0e+00	487	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
650745243	469	35.35	57	466	20	423	5.0e-72	265	COG0823	Periplasmic component of the Tol biopolymer transport system	425
650745245	147	46.32	9	144	2	137	7.0e-35	139	COG0848	Biopolymer transport protein ExbD	137
650745246	238	44.04	22	237	1	216	5.0e-45	174	COG0811	Biopolymer transport protein ExbB/TolQ	216
650745247	166	41.22	16	146	5	134	2.0e-27	115	COG0824	Acyl-CoA thioesterase FadM	137
650745248	347	64.85	6	335	2	331	0.0e+00	490	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
650745249	204	37.13	1	202	1	200	1.0e-48	186	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
650745250	169	52.87	10	166	1	157	5.0e-45	173	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
650745251	253	58.09	5	245	1	241	4.0e-96	344	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
650745254	405	20.95	17	390	31	387	1.0e-11	64.8	COG2814	Predicted arabinose efflux permease, MFS family	394
650745256	147	46.26	1	145	6	150	8.0e-31	126	COG3624	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG	151
650745257	187	42.63	4	185	6	195	7.0e-30	123	COG3625	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH	196
650745258	360	65.74	1	358	1	358	0.0e+00	516	COG3626	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI	367
650745259	277	73.19	1	276	9	284	0.0e+00	479	COG3627	Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase	291
650745260	254	66.53	3	252	6	256	9.0e-93	333	COG4107	ABC-type phosphonate transport system, ATPase component	258
650745261	231	60	2	226	3	227	4.0e-80	291	COG4778	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL	235
650745262	373	48.27	5	373	4	377	7.0e-102	364	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
650745264	181	51.06	5	180	5	192	3.0e-39	155	COG3709	Ribose 1,5-bisphosphokinase PhnN	192
650745265	245	34.44	4	244	1	235	2.0e-40	159	COG2188	DNA-binding transcriptional regulator, GntR family	236
650745266	880	24.64	571	847	3	268	3.0e-20	94.4	COG1216	Glycosyltransferase, GT2 family	305
650745267	74	50	8	71	1	64	8.0e-11	58.7	COG0291	Ribosomal protein L35	65
650745268	118	62.61	1	115	1	115	8.0e-37	145	COG0292	Ribosomal protein L20	118
650745269	350	27.18	10	346	3	381	7.0e-26	111	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650745270	275	37.04	13	252	1	237	5.0e-58	218	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
650745271	141	25.4	12	131	7	122	1.0e-04	39.2	COG3631	Ketosteroid isomerase-related protein	133
650745272	334	52.54	1	334	4	338	5.0e-120	424	COG2130	NADPH-dependent curcumin reductase CurA	340
650745273	252	48	2	247	1	250	2.0e-77	282	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650745274	232	49.37	1	232	1	237	8.0e-78	283	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650745275	411	24.66	26	387	3	366	4.0e-34	139	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650745276	295	40.97	12	293	6	292	2.0e-41	162	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650745277	311	33.44	1	308	2	313	1.0e-41	163	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
650745278	493	36.38	3	491	1	475	8.0e-91	328	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
650745280	1110	34.01	24	532	1	505	1.0e-90	328	COG0366	Glycosidase	505
650745281	729	57.75	102	727	1	628	0.0e+00	760	COG0296	1,4-alpha-glucan branching enzyme	628
650745282	703	48.79	4	697	8	692	0.0e+00	758	COG1523	Pullulanase/glycogen debranching enzyme	697
650745283	664	35.39	152	658	12	517	5.0e-106	378	COG1640	4-alpha-glucanotransferase	520
650745285	337	20.88	23	288	1	267	3.0e-12	66.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
650745287	338	30.37	4	325	1	303	1.0e-33	137	COG3547	Transposase	303
650745292	307	50.86	24	307	7	279	8.0e-105	373	COG0408	Coproporphyrinogen III oxidase	303
650745294	395	25.87	1	372	2	371	2.0e-37	150	COG1290	Cytochrome b subunit of the bc complex	381
650745295	243	29.83	1	233	1	237	9.0e-33	133	COG2857	Cytochrome c1	250
650745296	297	40.48	6	252	14	262	4.0e-65	241	COG0005	Purine nucleoside phosphorylase	262
650745297	215	37.56	1	191	1	194	4.0e-57	214	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
650745298	268	65.08	17	268	3	253	2.0e-122	431	COG1117	ABC-type phosphate transport system, ATPase component	253
650745299	239	39.74	1	232	2	235	1.0e-44	173	COG0704	Phosphate uptake regulator	240
650745300	236	54.15	9	233	3	229	2.0e-62	232	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
650745302	486	25.15	1	480	2	486	3.0e-43	170	COG0591	Na+/proline symporter	493
650745303	245	24.65	17	231	14	214	1.0e-10	60.3	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
650745305	243	50.79	54	242	41	225	3.0e-57	215	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
650745307	472	48.47	10	452	6	457	2.0e-120	426	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
650745311	409	34.26	90	395	63	381	1.0e-33	137	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650745312	213	35.44	16	211	8	206	2.0e-23	102	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
650745313	493	20.3	10	437	16	458	5.0e-18	86.3	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
650745316	308	34.75	1	258	7	264	2.0e-39	156	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
650745318	346	22.01	12	275	20	328	7.0e-08	51.8	COG3146	Predicted N-acyltransferase	387
650745319	394	19.11	4	393	3	374	2.0e-11	64.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650745325	627	46.71	1	620	3	605	0.0e+00	601	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
650745326	358	35.81	1	355	2	349	3.0e-67	249	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
650745327	607	31.39	165	599	1	443	2.0e-88	320	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
650745329	185	24.85	16	182	8	174	3.0e-11	62.1	COG4961	Flp pilus assembly protein TadG	185
650745331	104	47.62	1	104	1	105	4.0e-30	123	COG3254	L-rhamnose mutarotase	105
650745332	323	42.33	13	310	13	306	1.0e-44	173	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650745333	352	42.17	42	352	5	315	5.0e-49	188	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
650745334	509	47.92	1	504	1	500	0.0e+00	539	COG1129	ABC-type sugar transport system, ATPase component	500
650745335	336	29.82	11	284	8	282	2.0e-37	149	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
650745336	260	42.63	11	259	3	252	9.0e-53	200	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
650745337	394	43.18	1	391	37	427	3.0e-116	412	COG4952	L-rhamnose isomerase	430
650745338	700	44.33	24	429	14	404	9.0e-110	391	COG3347	Rhamnose utilisation protein RhaD, predicted bifunctional aldolase and dehydrogenase	404
650745339	473	29.84	9	473	7	486	5.0e-63	235	COG1070	Sugar (pentulose or hexulose) kinase	502
650745340	631	32.84	213	592	1	408	8.0e-51	195	COG0840	Methyl-accepting chemotaxis protein	408
650745341	186	39.06	120	182	4	67	8.0e-08	50.5	COG1278	Cold shock protein, CspA family	67
650745342	306	32.83	2	276	4	335	1.0e-54	207	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
650745344	239	32.5	7	238	4	243	1.0e-39	156	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
650745345	210	40.31	4	189	19	209	4.0e-36	144	COG4117	Thiosulfate reductase cytochrome b subunit	221
650745347	218	26.35	46	212	9	155	6.0e-15	74.5	COG1225	Peroxiredoxin	157
650745348	289	30.93	1	285	1	289	1.0e-24	107	COG0583	DNA-binding transcriptional regulator, LysR family	297
650745349	198	25.4	1	187	1	177	3.0e-17	82.2	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
650745350	356	51.59	1	347	1	337	2.0e-119	422	COG3839	ABC-type sugar transport system, ATPase component	338
650745351	278	35.4	6	276	11	278	1.0e-46	180	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
650745352	292	38.83	2	290	1	290	1.0e-53	203	COG1175	ABC-type sugar transport system, permease component	295
650745353	442	23.93	1	436	6	433	4.0e-34	139	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
650745354	390	42.28	270	389	1	123	6.0e-20	92.4	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
650745355	760	22.05	52	759	38	731	6.0e-55	209	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
650745356	161	48	2	150	1	150	5.0e-48	183	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
650745357	182	28.69	14	135	1	122	2.0e-12	65.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
650745359	434	37.88	15	425	20	447	3.0e-102	365	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
650745360	132	28.57	21	115	24	117	6.0e-04	36.5	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
650745361	306	19.09	33	256	10	222	7.0e-08	51.5	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
650745362	488	25.31	3	472	1	446	3.0e-53	203	COG0527	Aspartokinase	447
650745363	409	20.16	1	379	8	391	2.0e-12	67.5	COG2814	Predicted arabinose efflux permease, MFS family	394
650745364	201	21.05	8	197	15	200	9.0e-07	47.3	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
650745365	329	19.75	1	320	1	289	2.0e-17	83.6	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
650745366	249	48.37	7	247	8	250	1.0e-68	253	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
650745367	362	39.84	112	361	21	266	4.0e-44	172	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
650745368	212	29.86	18	210	18	223	6.0e-23	101	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
650745369	445	47.1	1	444	1	438	0.0e+00	474	COG0015	Adenylosuccinate lyase	438
650745370	239	31.25	1	198	1	202	1.0e-19	90.1	COG3332	Uncharacterized conserved protein, contains NRDE domain	270
650745371	497	42.24	4	484	1	472	1.0e-129	456	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
650745372	442	23.58	37	437	4	409	1.0e-42	167	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
650745374	600	29.53	158	592	1	443	4.0e-85	309	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
650745375	162	35.09	50	162	6	112	1.0e-13	69.9	COG1416	Intracellular sulfur oxidation protein, DsrE/DsrF family	112
650745376	277	25.09	39	272	19	282	1.0e-09	57	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
650745377	612	40.91	14	608	98	709	4.0e-123	435	COG2217	Cation transport ATPase	713
650745379	258	50.4	7	258	3	254	2.0e-80	292	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
650745380	606	44.37	154	605	5	445	1.0e-118	420	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
650745381	471	31.17	196	471	23	327	8.0e-51	195	COG0280	Phosphotransacetylase	327
650745382	116	35.64	6	106	14	114	2.0e-13	68.1	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
650745383	167	35.26	6	158	9	155	1.0e-08	52.5	COG4960	Flp pilus assembly protein, protease CpaA	168
650745384	448	29.06	9	433	5	428	2.0e-45	176	COG1457	Purine-cytosine permease or related protein	442
650745389	259	30.14	13	229	1	213	3.0e-36	145	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
650745390	197	28.4	31	195	28	187	3.0e-11	62	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
650745395	114	25.86	1	114	20	127	5.0e-03	33.4	COG2010	Cytochrome c, mono- and diheme variants	150
650745396	164	30.77	64	164	44	147	2.0e-11	62.4	COG5501	Predicted secreted protein	148
650745400	578	25.96	95	545	37	477	2.0e-52	200	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
650745401	145	29.25	41	145	11	112	5.0e-06	43.7	COG1416	Intracellular sulfur oxidation protein, DsrE/DsrF family	112
650745402	273	34.11	12	268	3	256	3.0e-09	55.8	COG0730	Uncharacterized membrane protein YfcA	258
650745405	129	33.01	11	111	19	121	1.0e-14	72.3	COG3439	Uncharacterized conserved protein, DUF302 family	137
650745407	392	44.84	5	392	3	395	5.0e-119	421	COG0282	Acetate kinase	396
650745408	310	30.27	9	187	45	227	1.0e-26	114	COG2114	Adenylate cyclase, class 3	227
650745409	477	45.99	10	476	1	442	0.0e+00	524	COG0174	Glutamine synthetase	443
650745410	112	73.21	1	112	1	112	9.0e-37	145	COG0347	Nitrogen regulatory protein PII	112
650745411	394	36.34	22	391	21	393	2.0e-83	303	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
650745412	284	37.01	6	282	2	263	3.0e-48	185	COG0388	Predicted amidohydrolase	274
650745413	253	28.85	4	252	25	276	4.0e-43	168	COG0061	NAD kinase	281
650745414	175	41.42	2	169	16	182	8.0e-30	123	COG2320	GrpB domain, predicted nucleotidyltransferase, UPF0157 family	185
650745415	327	30.86	6	327	1	312	2.0e-60	226	COG0039	Malate/lactate dehydrogenase	313
650745416	195	23.2	10	186	11	169	3.0e-06	45.3	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
650745418	313	33.78	4	295	3	295	2.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
650745419	161	24.84	1	146	3	153	2.0e-16	78.4	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
650745420	882	40.32	12	882	1	786	0.0e+00	745	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
650745421	372	29.54	3	369	2	346	9.0e-18	84.8	COG3515	Predicted component of the type VI protein secretion system	346
650745422	497	37.59	58	494	68	493	9.0e-103	367	COG3517	Predicted component of the type VI protein secretion system	495
650745423	497	53.69	1	497	1	494	0.0e+00	678	COG3517	Predicted component of the type VI protein secretion system	495
650745424	168	53.7	4	165	3	164	1.0e-50	192	COG3516	Predicted component of the type VI protein secretion system	169
650745425	271	38.76	15	270	10	265	2.0e-44	172	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion	273
650745426	173	36.05	21	167	10	153	2.0e-17	81.9	COG3518	Predicted component of the type VI protein secretion system	157
650745427	605	41.53	1	605	1	621	0.0e+00	499	COG3519	Type VI protein secretion system component VasA	621
650745428	369	34.15	20	339	14	325	6.0e-46	178	COG3520	Predicted component of the type VI protein secretion system	335
650745431	197	23.89	22	196	28	207	1.0e-13	69.9	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
650745432	232	30.41	12	222	6	216	6.0e-22	97.7	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
650745433	218	28.9	8	175	11	181	3.0e-13	68.7	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
650745434	308	25.73	1	306	4	297	3.0e-23	102	COG2177	Cell division protein FtsX	297
650745435	223	49.32	1	219	1	215	3.0e-71	261	COG2884	ABC-type ATPase involved in cell division	223
650745437	349	35.4	11	328	3	311	9.0e-63	234	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
650745438	606	46.1	9	602	7	619	0.0e+00	642	COG0326	Molecular chaperone, HSP90 family	623
650745440	98	43.68	11	97	5	90	6.0e-16	75.7	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
650745441	110	42.19	4	63	5	66	6.0e-08	49.4	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
650745442	266	47.5	104	263	1	160	7.0e-45	174	COG1329	RNA polymerase-interacting regulator, CarD/CdnL/TRCF family	166
650745443	433	42.89	25	426	10	413	5.0e-70	258	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
650745444	245	55.08	4	238	1	236	4.0e-86	311	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
650745445	660	54.72	403	655	2	250	1.0e-79	291	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
650745446	306	42.24	1	302	3	294	2.0e-48	186	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
650745447	411	32.43	25	391	4	356	3.0e-40	159	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
650745448	671	27.78	24	666	13	605	1.0e-64	241	COG4206	Outer membrane cobalamin receptor protein	608
650745449	227	32.59	7	224	4	226	1.0e-28	120	COG1011	FMN phosphatase YigB, HAD superfamily	229
650745450	232	28.71	20	220	9	195	6.0e-14	71.4	COG0625	Glutathione S-transferase	211
650745452	212	22.16	12	204	5	196	2.0e-09	55.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
650745453	221	35.1	7	208	4	206	1.0e-34	140	COG3531	Predicted protein-disulfide isomerase , contains CxxC motif	212
650745454	394	46.43	6	394	6	396	1.0e-121	430	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
650745455	90	46.59	1	88	1	88	3.0e-11	60.3	COG0268	Ribosomal protein S20	88
650745457	93	61.8	1	89	1	89	7.0e-24	102	COG5606	Predicted DNA-binding protein, XRE-type HTH domain	91
650745458	91	57.78	2	91	26	115	2.0e-25	107	COG4679	Phage-related protein	116
650745459	219	28.05	1	199	2	246	8.0e-22	97.2	COG1192	Cellulose biosynthesis protein BcsQ	259
650745462	80	37.04	1	79	1	81	1.0e-07	48	COG4423	Uncharacterized protein	81
650745463	136	43.18	2	132	1	129	1.0e-29	122	COG3742	Uncharacterized protein, contains PIN domain	131
650745466	235	30.61	33	225	1	184	3.0e-33	135	COG0431	NAD(P)H-dependent FMN reductase	184
650745467	439	39.53	1	429	4	424	4.0e-78	285	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
650745468	140	39.32	1	117	1	117	7.0e-34	136	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
650745469	174	32.64	5	143	2	136	8.0e-27	113	COG0394	Protein-tyrosine-phosphatase	139
650745470	130	26.36	1	110	2	109	2.0e-09	54.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
650745471	160	29.38	1	144	7	164	4.0e-14	71	COG0723	Rieske Fe-S protein	177
650745472	804	22.11	17	784	38	696	1.0e-55	211	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
650745475	264	35.71	13	246	13	249	4.0e-43	168	COG1484	DNA replication protein DnaC	254
650745476	512	24.44	15	279	14	261	5.0e-15	76.3	COG4584	Transposase	278
650745477	338	30.37	4	325	1	303	3.0e-33	135	COG3547	Transposase	303
650745478	621	35.6	8	196	11	201	3.0e-25	110	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
650745483	107	32.08	1	106	6	110	3.0e-14	70.3	COG4679	Phage-related protein	116
650745485	770	30.27	4	751	40	895	7.0e-116	411	COG0474	Magnesium-transporting ATPase (P-type)	917
650745493	722	21.18	23	634	10	645	6.0e-28	119	COG1743	Adenine-specific DNA methylase, contains a Zn-ribbon domain	875
650745495	195	45.36	5	181	4	197	1.0e-32	132	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650745496	224	45.81	1	224	1	225	8.0e-51	193	COG2135	Putative SOS response-associated peptidase YedK	226
650745498	418	28.65	2	354	1	352	5.0e-51	195	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
650745499	678	23.67	184	668	98	563	6.0e-66	245	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
650745508	988	40.73	619	946	1	323	2.0e-74	274	COG4644	Transposase and inactivated derivatives, TnpA family	323
650745509	193	35.29	4	193	2	205	2.0e-27	115	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650745510	355	28.57	17	320	8	289	9.0e-58	217	COG0630	Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase	312
650745512	378	30	15	375	1	359	3.0e-49	189	COG2948	Type IV secretory pathway, VirB10 components	360
650745513	296	28.52	17	293	19	264	2.0e-30	126	COG3504	Type IV secretory pathway, VirB9 components	265
650745514	233	30.73	13	228	14	229	7.0e-33	133	COG3736	Type IV secretory pathway, component VirB8	239
650745516	295	18.73	1	287	36	334	3.0e-12	65.8	COG3704	Type IV secretory pathway, VirB6 components	406
650745519	797	33.08	7	795	12	794	0.0e+00	553	COG3451	Type IV secretory pathway, VirB4 component	796
650745520	110	39.18	7	102	8	102	6.0e-14	69.5	COG3702	Type IV secretory pathway, VirB3 components	105
650745521	121	30	32	121	14	103	6.0e-06	42.9	COG3838	Type IV secretory pathway, VirB2 components (pilins)	108
650745524	134	30	41	100	5	64	7.0e-04	36.3	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
650745531	81	26.58	1	79	2	78	2.0e-06	43.9	COG4118	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor	84
650745532	128	48.36	2	122	3	124	8.0e-27	112	COG3744	PIN domain nuclease, a component of toxin-antitoxin system (PIN domain)	130
650745534	988	40.73	619	946	1	323	2.0e-74	274	COG4644	Transposase and inactivated derivatives, TnpA family	323
650745535	193	35.29	4	193	2	205	2.0e-27	115	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650745536	930	35.14	625	919	1	291	2.0e-55	211	COG4644	Transposase and inactivated derivatives, TnpA family	323
650745537	215	39.34	1	196	2	211	4.0e-28	118	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650745540	141	28.28	1	140	3	133	1.0e-10	59	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
650745542	947	22.81	48	762	15	683	6.0e-72	266	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
650745544	293	27.52	37	293	8	263	1.0e-34	140	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
650745545	275	41.39	1	244	1	239	7.0e-77	280	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
650745546	352	54.31	3	349	2	337	0.0e+00	482	COG1088	dTDP-D-glucose 4,6-dehydratase	340
650745547	293	54.9	3	288	1	283	7.0e-102	363	COG1209	dTDP-glucose pyrophosphorylase	286
650745548	184	49.72	1	177	2	173	2.0e-53	202	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
650745549	301	44.95	5	291	2	277	2.0e-73	269	COG1091	dTDP-4-dehydrorhamnose reductase	281
650745552	750	27.76	485	742	1	255	2.0e-22	101	COG1216	Glycosyltransferase, GT2 family	305
650745554	399	21.69	107	377	100	377	2.0e-09	57.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
650745555	192	42.13	10	190	4	200	2.0e-31	128	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
650745558	181	37.57	1	179	4	181	2.0e-22	98.8	COG3038	Cytochrome b561	181
650745559	230	37.77	39	225	4	191	5.0e-32	131	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
650745567	227	22.14	1	222	2	258	1.0e-14	73.3	COG1192	Cellulose biosynthesis protein BcsQ	259
