gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
648282965	573	42.57	19	567	3	548	0.0e+00	496	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
648282966	685	41.83	5	681	3	674	0.0e+00	561	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
648282967	241	34.89	2	236	4	230	2.0e-25	109	COG1802	DNA-binding transcriptional regulator, GntR family	230
648282968	322	38.79	4	322	6	311	8.0e-77	280	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
648282969	239	52.74	5	239	1	235	7.0e-77	280	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
648282970	254	53.57	1	252	1	249	2.0e-76	279	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
648282971	327	37.5	11	316	3	313	7.0e-35	141	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
648282972	289	38.57	1	288	5	297	8.0e-39	154	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
648282973	392	28.82	31	374	7	349	4.0e-40	159	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648282974	206	23.15	4	204	1	201	6.0e-08	50.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648282976	241	36.08	1	239	1	251	7.0e-35	140	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648282977	542	44.4	3	542	1	537	0.0e+00	553	COG1069	Ribulose kinase	544
648282978	243	34.29	2	241	1	245	1.0e-62	232	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
648282979	307	52.44	1	305	2	307	1.0e-57	216	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
648282980	500	52.32	1	494	8	500	0.0e+00	616	COG1129	ABC-type sugar transport system, ATPase component	500
648282981	304	35.6	4	304	10	317	2.0e-42	166	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
648282982	294	34.31	183	284	22	122	6.0e-19	88.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
648282983	350	34.28	6	348	1	350	4.0e-65	241	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
648282984	333	38.92	1	312	3	314	1.0e-85	310	COG0180	Tryptophanyl-tRNA synthetase	314
648282985	387	61.79	1	369	1	366	0.0e+00	522	COG1062	Zn-dependent alcohol dehydrogenase	366
648282986	340	37.46	15	337	11	327	6.0e-67	248	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
648282988	162	52.26	2	156	50	204	1.0e-45	176	COG4337	Uncharacterized protein	206
648282991	254	48.22	1	249	1	253	5.0e-80	290	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
648282992	345	41.89	12	345	3	333	2.0e-48	186	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
648282993	339	23.74	5	333	8	312	7.0e-27	114	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
648282994	490	47.42	24	486	2	466	0.0e+00	486	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648282995	347	50	1	346	1	346	2.0e-125	442	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
648282996	483	46.95	10	483	1	469	7.0e-126	444	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648282997	465	20.62	10	427	1	394	3.0e-15	76.9	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
648282999	661	40.62	1	574	1	562	0.0e+00	559	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
648283000	685	40	14	683	2	673	0.0e+00	529	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
648283001	301	32.56	5	300	1	297	4.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
648283002	367	32.37	1	367	5	383	7.0e-43	168	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648283003	441	29.67	14	432	1	383	5.0e-46	178	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648283004	164	41.56	3	156	2	154	1.0e-34	139	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648283005	554	45.39	1	536	1	539	0.0e+00	570	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
648283006	289	36.24	5	289	1	287	4.0e-56	211	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648283007	319	39.74	10	319	4	315	4.0e-70	258	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648283008	536	26.2	19	534	1	556	2.0e-71	264	COG0747	ABC-type transport system, periplasmic component	556
648283009	246	27.9	15	239	6	228	5.0e-24	104	COG1011	FMN phosphatase YigB, HAD superfamily	229
648283010	300	33.54	1	300	3	324	3.0e-52	199	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
648283011	456	42.86	2	450	1	449	0.0e+00	490	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
648283013	365	33.5	1	364	13	406	2.0e-53	203	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648283014	144	44.26	23	144	1	116	1.0e-26	112	COG3450	Predicted enzyme of the cupin superfamily	116
648283015	221	24	4	219	3	226	5.0e-23	101	COG1011	FMN phosphatase YigB, HAD superfamily	229
648283016	429	26.65	23	409	2	385	6.0e-55	208	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648283019	449	41.4	12	447	3	440	8.0e-84	304	COG3182	Uncharacterized iron-regulated membrane protein	442
648283021	432	34.21	54	432	2	378	7.0e-67	248	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648283022	165	24.85	1	164	2	164	3.0e-10	58	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648283023	326	28.57	1	324	6	327	3.0e-32	133	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648283025	107	33.64	1	106	1	102	3.0e-12	63.5	COG0633	Ferredoxin	102
648283026	391	31.02	1	391	16	410	3.0e-62	232	COG2124	Cytochrome P450	411
648283027	300	25.42	11	300	1	293	1.0e-23	104	COG0583	DNA-binding transcriptional regulator, LysR family	297
648283028	254	26.67	3	196	7	203	7.0e-17	81	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648283030	400	38.87	2	390	1	390	2.0e-49	190	COG2814	Predicted arabinose efflux permease, MFS family	394
648283031	296	29.74	1	295	20	296	9.0e-26	110	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
648283032	297	32.54	6	296	3	290	9.0e-35	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
648283034	372	41.76	1	363	3	358	4.0e-87	315	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
648283035	308	30.43	7	301	2	293	4.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
648283038	339	25.71	14	319	8	319	3.0e-31	129	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
648283040	726	33.65	13	725	1	731	0.0e+00	472	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
648283041	316	39.39	1	316	1	279	2.0e-55	209	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
648283042	213	53.53	45	213	1	155	3.0e-53	201	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
648283043	168	31.88	26	159	6	143	5.0e-17	80.9	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648283044	309	36.54	5	303	24	305	1.0e-53	204	COG0010	Arginase family enzyme	305
648283045	354	38.14	13	336	1	330	9.0e-87	313	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
648283046	332	36.36	101	331	19	257	2.0e-32	133	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
648283047	301	32.04	182	284	19	121	3.0e-18	86.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
648283048	689	27.19	1	680	39	741	3.0e-64	239	COG4774	Outer membrane receptor for monomeric catechols	750
648283049	278	25.38	19	277	54	311	6.0e-22	98.4	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
648283050	645	36.88	3	315	13	330	2.0e-31	131	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
648283051	257	46.43	6	256	4	255	1.0e-79	289	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
648283052	566	42.55	1	564	3	560	0.0e+00	480	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
648283053	260	32.77	7	239	3	236	3.0e-37	148	COG2188	DNA-binding transcriptional regulator, GntR family	236
648283056	451	34.52	2	448	1	474	3.0e-76	279	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
648283057	332	21.56	1	312	1	311	2.0e-23	103	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
648283058	249	48.8	2	249	1	243	2.0e-79	289	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
648283060	256	37.55	1	253	6	258	9.0e-48	183	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
648283061	379	42.12	1	379	2	388	4.0e-79	288	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648283062	286	34.58	49	286	54	291	2.0e-41	162	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
648283063	274	29.47	3	274	1	281	6.0e-12	65.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648283064	768	42.48	24	628	25	633	7.0e-116	411	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
648283065	320	26.79	4	317	5	318	7.0e-30	124	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
648283066	494	30.9	1	493	7	527	6.0e-85	308	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648283067	115	37.38	10	113	30	127	2.0e-16	77.3	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
648283068	390	32.08	3	388	1	392	4.0e-46	178	COG0183	Acetyl-CoA acetyltransferase	392
648283069	701	33.55	7	627	3	598	3.0e-94	340	COG1042	Acyl-CoA synthetase (NDP forming)	598
648283070	281	48.83	26	281	3	243	3.0e-76	278	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
648283071	282	37.35	32	280	10	258	2.0e-44	172	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
648283072	345	21.02	7	329	12	323	5.0e-17	82.2	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
648283073	200	25.27	13	194	6	175	3.0e-24	105	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
648283074	260	35.81	13	241	6	232	4.0e-47	181	COG2188	DNA-binding transcriptional regulator, GntR family	236
648283075	329	47.6	1	327	1	332	2.0e-97	349	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
648283076	326	41.61	38	320	32	317	1.0e-71	263	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
648283077	295	37.58	1	295	2	297	8.0e-68	250	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
648283078	494	47.83	11	491	15	497	1.0e-122	433	COG3333	TctA family transporter	504
648283079	319	30.09	1	315	4	318	5.0e-51	195	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
648283081	372	37.83	8	372	2	377	7.0e-93	334	COG1454	Alcohol dehydrogenase, class IV	377
648283082	340	25.79	3	332	1	407	7.0e-24	105	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
648283083	236	38.5	1	220	9	231	3.0e-38	152	COG2186	DNA-binding transcriptional regulator, FadR family	241
648283086	297	43.78	76	297	5	235	2.0e-48	186	COG0412	Dienelactone hydrolase	236
648283087	335	40.17	1	335	1	326	1.0e-58	220	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
648283088	244	31.48	1	214	1	213	1.0e-37	150	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
648283089	473	32.04	1	274	3	279	2.0e-47	183	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
648283090	306	48.16	5	300	1	298	9.0e-92	330	COG3246	Uncharacterized conserved protein, DUF849 family	298
648283092	260	40.08	1	257	3	257	7.0e-47	181	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648283093	681	31.94	1	608	1	597	3.0e-80	293	COG1042	Acyl-CoA synthetase (NDP forming)	598
648283094	386	38.78	1	382	1	388	9.0e-86	310	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648283095	272	33.21	3	270	6	267	1.0e-45	176	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
648283096	269	34.09	1	262	13	276	2.0e-47	182	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
648283097	370	27.86	30	369	10	357	2.0e-42	166	COG0687	Spermidine/putrescine-binding periplasmic protein	363
648283098	350	48.01	8	350	1	350	2.0e-110	392	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
648283099	334	23.75	37	327	1	295	2.0e-25	110	COG0583	DNA-binding transcriptional regulator, LysR family	297
648283100	243	29.22	9	226	3	217	3.0e-32	132	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
648283101	379	14.57	130	360	28	277	3.0e-10	59.6	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
648283102	297	29.59	5	291	1	289	1.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
648283104	112	32.97	10	100	19	107	3.0e-10	56.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
648283105	348	42.23	10	346	9	339	5.0e-73	268	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
648283106	237	29.59	30	222	1	184	6.0e-35	140	COG0431	NAD(P)H-dependent FMN reductase	184
648283107	392	41.03	12	392	17	404	9.0e-92	330	COG3347	Rhamnose utilisation protein RhaD, predicted bifunctional aldolase and dehydrogenase	404
648283108	296	38.61	28	275	1	259	2.0e-63	236	COG1830	Fructose-bisphosphate aldolase class Ia, DhnA family	265
648283109	512	32.6	1	493	2	499	1.0e-82	301	COG1070	Sugar (pentulose or hexulose) kinase	502
648283110	564	32.79	3	544	1	529	2.0e-96	346	COG0578	Glycerol-3-phosphate dehydrogenase	532
648283111	323	37.69	1	320	3	321	3.0e-64	238	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
648283112	333	46.2	20	332	3	315	1.0e-56	213	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
648283113	498	54.14	1	490	5	499	0.0e+00	601	COG1129	ABC-type sugar transport system, ATPase component	500
648283114	347	26.82	1	338	7	322	4.0e-38	152	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
648283115	376	32.98	1	367	15	372	5.0e-28	119	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
648283116	1053	47.28	1	1025	1	1007	0.0e+00	944	COG0841	Multidrug efflux pump subunit AcrB	1009
648283117	322	38.96	6	303	7	306	6.0e-80	291	COG4286	Uncharacterized protein, UPF0160 family	306
648283139	671	44.87	37	657	6	603	0.0e+00	523	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
648283154	110	37.5	1	108	28	139	2.0e-09	54.6	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
648283155	249	41.43	2	248	15	263	3.0e-67	248	COG2514	Catechol-2,3-dioxygenase	265
648283157	255	40.32	9	254	34	281	2.0e-42	166	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
648283166	306	26.82	21	299	1	297	4.0e-27	115	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
648283174	258	52.27	2	258	5	268	3.0e-91	328	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
648283176	224	62.67	1	217	6	222	6.0e-71	260	COG2011	ABC-type methionine transport system, permease component	222
648283177	353	55.69	11	351	2	339	7.0e-118	417	COG1135	ABC-type methionine transport system, ATPase component	339
648283181	382	32.99	1	382	1	369	6.0e-61	228	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
648283182	521	26.02	2	510	24	542	1.0e-63	237	COG0747	ABC-type transport system, periplasmic component	556
648283189	300	54.07	29	296	17	286	1.0e-73	270	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648283190	305	43.28	1	305	30	314	5.0e-77	281	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648283198	313	29	186	284	22	121	4.0e-12	66	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
648283199	293	42.32	1	289	5	295	5.0e-54	204	COG1175	ABC-type sugar transport system, permease component	295
648283201	307	36.79	29	306	4	281	3.0e-64	238	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648283205	370	51.81	1	359	1	338	5.0e-115	407	COG3839	ABC-type sugar transport system, ATPase component	338
648283222	237	26.23	2	235	42	279	4.0e-29	121	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
648283223	378	39.79	1	378	1	371	2.0e-78	286	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
648283229	519	28.34	23	510	2	469	2.0e-62	233	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648283232	425	51.98	46	424	1	378	2.0e-91	329	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648283234	158	32.48	1	157	2	158	2.0e-16	78.4	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648283235	322	39.44	1	321	8	329	3.0e-87	315	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648283239	247	41.57	5	245	1	251	5.0e-40	158	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648283241	375	53.6	105	375	1	278	7.0e-118	417	COG3717	5-keto 4-deoxyuronate isomerase	278
648283248	338	22.99	12	333	1	278	4.0e-26	112	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
648283249	176	34.65	45	169	6	131	6.0e-18	84.1	COG1917	Cupin domain protein related to quercetin dioxygenase	131
648283252	395	33.88	28	395	13	379	2.0e-65	243	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648283260	369	25	28	367	1	332	4.0e-33	135	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648283266	345	26.95	11	316	1	297	2.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
648283277	250	30.6	1	248	63	326	2.0e-23	103	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
648283280	242	39.76	7	240	2	251	6.0e-36	144	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648283281	257	43.32	2	239	8	251	5.0e-36	144	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648283282	369	40.8	1	323	22	328	1.0e-84	307	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
648283292	255	39.76	3	249	2	251	2.0e-43	169	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648283295	238	31.11	2	220	30	253	3.0e-36	145	COG0169	Shikimate 5-dehydrogenase	283
648283300	253	26.47	64	230	14	183	3.0e-07	49.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648283302	327	32.31	1	320	72	393	1.0e-57	217	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648283304	244	43.31	3	240	2	251	3.0e-37	148	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648283306	395	37.4	11	395	4	393	4.0e-77	282	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648283308	211	38.57	2	208	51	257	3.0e-34	138	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648283309	365	47.54	59	360	2	298	1.0e-85	310	COG3246	Uncharacterized conserved protein, DUF849 family	298
648283310	353	28.61	16	353	96	469	5.0e-42	165	COG0427	Acyl-CoA hydrolase	501
648283312	396	37.44	1	390	2	396	1.0e-84	307	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
648283314	137	30.28	15	122	18	125	5.0e-13	66.9	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
648283338	159	57.05	3	157	1	156	3.0e-52	197	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
648283340	316	41.75	32	315	4	284	4.0e-56	212	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
648283342	396	33.69	23	395	3	374	5.0e-61	228	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648283343	166	25.95	8	165	15	168	3.0e-07	48.4	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648283347	335	25	4	335	6	332	2.0e-33	136	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648283354	219	40.1	1	190	2	194	5.0e-33	134	COG2085	Predicted dinucleotide-binding enzyme	211
648283380	386	34.03	2	383	14	396	8.0e-76	277	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
648283385	267	35.34	18	263	12	257	4.0e-40	158	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648283386	325	40.18	2	324	84	392	2.0e-63	236	COG0183	Acetyl-CoA acetyltransferase	392
648283389	386	36.6	7	386	8	393	9.0e-79	287	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648283390	656	38.25	83	628	1	522	0.0e+00	467	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
648283391	297	32.64	6	292	1	277	1.0e-41	163	COG2301	Citrate lyase beta subunit	283
648283392	266	41.2	3	263	2	251	2.0e-40	160	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648283393	413	20.78	40	395	39	384	2.0e-09	57.1	COG2814	Predicted arabinose efflux permease, MFS family	394
648283398	489	45.78	9	478	2	465	2.0e-121	430	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648283402	280	32.39	57	266	13	224	2.0e-29	123	COG1802	DNA-binding transcriptional regulator, GntR family	230
648283404	262	39.3	8	257	1	249	3.0e-41	162	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648283405	481	37.69	78	467	2	396	2.0e-78	286	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
648283407	413	36.64	31	408	4	394	7.0e-78	284	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
648283409	247	48.81	2	244	6	255	8.0e-64	237	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
648283418	391	21.73	14	389	83	410	3.0e-12	66.7	COG2124	Cytochrome P450	411
648283420	104	34.07	11	100	32	120	7.0e-12	62.3	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
648283437	247	23.89	7	231	2	226	3.0e-23	102	COG2188	DNA-binding transcriptional regulator, GntR family	236
648283443	428	43.28	37	426	2	392	2.0e-78	286	COG0183	Acetyl-CoA acetyltransferase	392
648283450	395	40.91	1	391	1	396	3.0e-101	362	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
648283452	345	35.55	1	345	4	338	7.0e-82	297	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
648283509	158	46.38	1	133	4	141	5.0e-34	137	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
648283511	234	30.56	14	227	52	266	2.0e-25	109	COG4233	Thiol-disulfide interchange protein, contains DsbC and DsbD domains	273
648283512	1129	24.76	10	1029	1	1005	8.0e-125	441	COG0841	Multidrug efflux pump subunit AcrB	1009
648283514	180	47.59	10	173	5	169	2.0e-46	178	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
648283516	264	45.05	75	263	1	202	1.0e-42	167	COG1573	Uracil-DNA glycosylase	202
648283517	316	48.72	1	303	3	310	4.0e-100	357	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
648283520	427	43.74	4	425	3	421	3.0e-102	365	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
648283521	205	45.92	12	200	5	200	6.0e-45	173	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
648283522	186	42.08	1	183	5	180	3.0e-42	164	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
648283523	169	46.71	2	156	1	167	2.0e-42	164	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
648283525	199	36.22	4	196	10	201	5.0e-30	124	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
648283526	336	55.03	8	324	6	314	1.0e-106	379	COG0462	Phosphoribosylpyrophosphate synthetase	314
648283528	144	33.33	4	102	3	104	9.0e-16	76.1	COG0355	FoF1-type ATP synthase, epsilon subunit	135
648283529	474	76.16	4	472	2	468	0.0e+00	804	COG0055	FoF1-type ATP synthase, beta subunit	468
648283530	293	44.83	5	293	1	286	4.0e-85	308	COG0224	FoF1-type ATP synthase, gamma subunit	287
648283531	512	67.58	1	512	1	501	0.0e+00	799	COG0056	FoF1-type ATP synthase, alpha subunit	504
648283532	186	41.57	6	183	2	178	5.0e-34	137	COG0712	FoF1-type ATP synthase, delta subunit	178
648283534	251	30.99	9	220	22	248	2.0e-22	99	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648283535	776	46.62	4	758	2	784	0.0e+00	840	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
648283536	237	32.6	2	225	14	233	1.0e-26	113	COG2186	DNA-binding transcriptional regulator, FadR family	241
648283537	225	36.82	1	194	1	200	1.0e-28	120	COG3342	Uncharacterized conserved protein, Ntn-hydrolase superfamily	265
648283538	525	35.29	1	525	1	553	4.0e-95	342	COG0747	ABC-type transport system, periplasmic component	556
648283539	315	46.67	1	315	1	315	1.0e-90	327	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648283540	625	53.92	302	618	1	316	9.0e-118	418	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
648283542	398	50	23	383	1	349	7.0e-119	420	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
648283544	828	49.06	70	808	3	712	0.0e+00	693	COG2217	Cation transport ATPase	713
648283545	129	30.83	1	118	1	120	2.0e-20	91.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
648283547	493	46.2	21	492	1	468	0.0e+00	514	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648283551	201	41.8	9	195	16	194	5.0e-32	130	COG3145	Alkylated DNA repair dioxygenase AlkB	194
648283553	642	61.92	1	602	4	579	0.0e+00	683	COG0443	Molecular chaperone DnaK (HSP70)	579
648283554	385	55.99	1	382	1	371	0.0e+00	465	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
648283555	205	36.18	8	202	11	205	4.0e-30	124	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
648283556	253	39.45	36	253	7	224	2.0e-61	228	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
648283557	517	22.64	359	517	36	188	1.0e-11	64.9	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
648283559	915	55.26	4	905	1	820	0.0e+00	1043	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
648283560	286	24.65	11	276	27	309	2.0e-13	69.7	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
648283561	409	48.53	7	409	1	404	5.0e-122	431	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
648283562	133	33.06	1	121	5	127	7.0e-11	59.7	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
648283564	822	58.58	318	822	1	507	0.0e+00	628	COG0532	Translation initiation factor IF-2, a GTPase	509
648283565	217	41.86	14	97	7	92	5.0e-18	84.6	COG2740	Predicted RNA-binding protein YlxR, DUF448 family	95
648283566	542	54.59	164	358	1	190	1.0e-50	194	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
648283567	195	38.36	5	162	1	153	5.0e-34	137	COG0779	Ribosome maturation factor RimP	153
648283569	506	40.28	1	504	1	497	8.0e-107	381	COG0557	Exoribonuclease R	706
648283570	466	31.28	5	443	4	454	1.0e-80	294	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
648283571	381	31.82	4	381	14	409	1.0e-69	257	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648283574	342	23.58	4	337	6	316	9.0e-19	88	COG0530	Ca2+/Na+ antiporter	320
648283575	81	45.68	3	81	1	81	6.0e-06	42.3	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
648283576	275	50.18	4	275	2	270	7.0e-84	303	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
648283578	160	22.36	3	157	1	151	1.0e-07	49.2	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
648283579	448	45.14	27	399	24	398	4.0e-98	351	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
648283580	371	23.17	1	366	12	418	5.0e-25	108	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
648283581	504	54.21	2	504	1	508	0.0e+00	639	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
648283583	1110	65.13	13	425	1	397	0.0e+00	544	COG0458	Carbamoylphosphate synthase large subunit	400
648283584	410	51.94	103	384	1	283	3.0e-97	349	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
648283585	593	48.65	4	592	1	585	0.0e+00	809	COG0173	Aspartyl-tRNA synthetase	585
648283586	400	32.31	16	392	3	378	2.0e-48	186	COG0006	Xaa-Pro aminopeptidase	384
648283590	289	21.77	1	287	1	281	3.0e-17	83	COG3302	DMSO reductase anchor subunit	281
648283591	249	42.79	10	216	9	198	1.0e-50	193	COG0437	Fe-S-cluster-containing dehydrogenase component	203
648283594	421	20.46	1	381	1	380	4.0e-17	82.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648283596	431	27.22	103	423	66	381	3.0e-30	126	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648283597	683	38.42	4	356	1	366	1.0e-50	195	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
648283599	254	30.04	10	230	15	233	1.0e-33	137	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
648283600	375	25.21	1	348	2	341	2.0e-29	123	COG0673	Predicted dehydrogenase	342
648283601	326	28.63	10	242	2	246	9.0e-19	88.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
648283602	411	34.94	110	401	69	380	8.0e-38	151	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648283603	319	23.3	1	254	2	277	6.0e-18	85.2	COG1216	Glycosyltransferase, GT2 family	305
648283604	699	28.38	4	300	3	305	6.0e-36	146	COG0673	Predicted dehydrogenase	342
648283605	204	24.73	22	200	1	181	7.0e-07	47.7	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
648283606	129	40.5	5	125	13	132	5.0e-23	100	COG3824	Predicted Zn-dependent protease, minimal metalloprotease (MMP)-like domain	136
648283607	552	39.86	265	541	6	268	1.0e-65	244	COG0171	NH3-dependent NAD+ synthetase	268
648283608	488	32.37	145	283	1	139	8.0e-18	85.4	COG4642	Uncharacterized conserved protein	139
648283610	299	29.55	15	298	7	294	3.0e-36	145	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
648283611	350	23.85	1	344	3	348	4.0e-27	115	COG0628	Predicted PurR-regulated permease PerM	355
648283612	197	26.83	26	188	27	188	1.0e-18	86.4	COG3932	Uncharacterized conserved protein	209
648283614	275	27.82	3	266	2	276	8.0e-19	87.7	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
648283615	309	28.29	9	309	3	301	1.0e-32	133	COG1597	Diacylglycerol kinase family enzyme	301
648283617	805	61.39	8	568	3	560	0.0e+00	877	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
648283618	369	34.89	4	360	1	360	3.0e-76	279	COG1195	Recombinational DNA repair ATPase RecF	363
648283619	372	43.28	1	372	1	364	2.0e-87	316	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
648283620	451	43.62	3	447	6	408	1.0e-115	410	COG0593	Chromosomal replication initiation ATPase DnaA	408
648283621	87	55.81	1	86	1	86	3.0e-14	69.9	COG0268	Ribosomal protein S20	88
648283623	258	44.36	1	253	2	256	2.0e-60	226	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648283624	283	50	1	283	1	273	2.0e-92	332	COG0266	Formamidopyrimidine-DNA glycosylase	273
648283625	250	48.54	13	250	1	238	2.0e-80	292	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
648283626	510	41.88	1	506	1	503	9.0e-124	437	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
648283627	338	29.53	5	336	1	314	4.0e-48	185	COG0451	Nucleoside-diphosphate-sugar epimerase	314
648283628	224	28.05	5	221	2	220	3.0e-21	95.5	COG1843	Flagellar hook assembly protein FlgD	222
648283633	125	29.47	25	118	21	114	6.0e-10	56.5	COG5442	Flagellar biosynthesis regulator FlaF	115
648283634	134	27.27	2	133	3	132	1.0e-13	68.8	COG5443	Flagellar biosynthesis regulator FlbT	148
648283636	453	44.16	5	436	8	440	1.0e-119	423	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
648283637	125	27.48	1	123	4	130	8.0e-12	62.6	COG1815	Flagellar basal body rod protein FlgB	133
648283638	130	34.06	1	128	1	137	7.0e-27	113	COG1558	Flagellar basal body rod protein FlgC	137
648283639	96	32.5	18	96	26	105	5.0e-08	49.2	COG1677	Flagellar hook-basal body complex protein FliE	105
648283640	89	31.65	2	80	1	79	3.0e-10	57.1	COG1987	Flagellar biosynthesis protein FliQ	89
648283641	237	35.02	6	233	6	262	2.0e-48	185	COG4786	Flagellar basal body rod protein FlgG	265
648283642	261	44.91	1	261	2	264	2.0e-69	255	COG4786	Flagellar basal body rod protein FlgG	265
648283644	242	36.02	4	239	3	230	4.0e-48	184	COG2063	Flagellar basal body L-ring protein FlgH	230
648283647	330	33.33	2	327	34	358	1.0e-67	250	COG1377	Flagellar biosynthesis protein FlhB	363
648283648	255	28.16	10	252	7	249	2.0e-22	99.4	COG1684	Flagellar biosynthesis protein FliR	258
648283649	691	40	12	689	21	693	0.0e+00	584	COG1298	Flagellar biosynthesis pathway, component FlhA	696
648283651	289	35.66	1	285	3	265	1.0e-55	210	COG1291	Flagellar motor component MotA	266
648283652	370	51.75	1	370	1	365	2.0e-106	378	COG1706	Flagellar basal body P-ring protein FlgI	365
648283653	334	16	10	334	9	358	3.0e-08	53.2	COG1344	Flagellin and related hook-associated protein FlgL	360
648283654	486	22.99	1	486	1	550	8.0e-38	152	COG1256	Flagellar hook-associated protein FlgK	552
648283655	432	27.5	6	432	4	423	2.0e-49	190	COG1749	Flagellar hook protein FlgE	423
648283656	277	22.3	11	276	1	242	2.0e-26	113	COG1360	Flagellar motor protein MotB	244
648283659	203	35.64	2	200	38	220	8.0e-37	146	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
648283660	363	28.17	62	270	35	239	5.0e-23	102	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
648283661	142	34.48	7	141	5	133	2.0e-15	74.6	COG3474	Cytochrome c2	135
648283662	173	35.19	17	172	20	179	4.0e-24	104	COG1443	Isopentenyldiphosphate isomerase	185
648283663	181	36.21	10	181	21	182	3.0e-19	88.4	COG2840	DNA-nicking endonuclease, Smr domain	184
648283664	347	38.51	36	334	35	365	1.0e-71	263	COG2821	Membrane-bound lytic murein transglycosylase	373
648283665	219	25.65	8	217	51	277	4.0e-25	108	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
648283666	183	37.66	3	148	5	158	3.0e-25	108	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
648283667	169	38.36	1	159	1	149	7.0e-35	140	COG1952	Preprotein translocase subunit SecB	157
648283668	229	36.68	1	227	13	237	3.0e-44	171	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
648283669	196	37.69	1	196	1	199	2.0e-43	168	COG0237	Dephospho-CoA kinase	201
648283670	276	43.17	1	275	1	278	9.0e-83	300	COG0169	Shikimate 5-dehydrogenase	283
648283671	199	31.61	1	192	1	185	6.0e-41	160	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
648283673	423	70.48	4	423	2	420	0.0e+00	677	COG1158	Transcription termination factor Rho	422
648283674	373	41.92	2	373	61	454	8.0e-98	350	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
648283675	622	55.72	3	620	2	621	0.0e+00	870	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
648283676	181	29.71	1	169	30	200	1.0e-28	119	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
648283677	269	43.41	9	263	1	253	1.0e-55	210	COG1192	Cellulose biosynthesis protein BcsQ	259
648283678	303	39	39	293	4	238	1.0e-32	133	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
648283679	383	40.66	1	383	26	410	8.0e-99	354	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
648283680	203	45.08	7	198	1	187	5.0e-55	207	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
648283681	237	52.12	1	235	8	228	4.0e-68	251	COG0689	Ribonuclease PH	230
648283682	354	41.81	10	350	3	340	2.0e-88	319	COG1420	Transcriptional regulator of heat shock response	346
648283683	185	39.44	3	180	12	190	5.0e-33	133	COG0576	Molecular chaperone GrpE (heat shock protein)	193
648283684	874	46.75	1	870	9	843	0.0e+00	863	COG0249	DNA mismatch repair ATPase MutS	843
648283685	751	56.78	3	427	13	426	0.0e+00	576	COG0281	Malic enzyme	432
648283686	292	37.67	6	287	5	304	2.0e-39	156	COG0524	Sugar or nucleoside kinase, ribokinase family	311
648283687	215	50	30	171	9	152	3.0e-51	195	COG0225	Peptide methionine sulfoxide reductase MsrA	174
648283689	298	33.68	19	298	3	282	6.0e-47	181	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
648283692	182	41.27	48	173	7	132	1.0e-26	112	COG5579	Uncharacterized protein, DUF1810 family	143
648283693	406	57	1	405	1	403	0.0e+00	586	COG0137	Argininosuccinate synthase	403
648283695	414	44.09	7	344	6	347	2.0e-98	352	COG1171	Threonine dehydratase	347
648283697	415	27.74	125	414	96	367	2.0e-27	117	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
648283698	145	25.66	23	131	16	124	1.0e-06	45.8	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
648283699	327	32.81	10	321	4	283	7.0e-61	227	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
648283700	191	21.43	27	157	7	141	3.0e-06	45.4	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
648283701	363	30.53	2	351	18	390	1.0e-51	196	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
648283702	194	27.41	6	194	9	205	4.0e-16	78	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
648283703	614	36.43	23	604	1	567	5.0e-116	411	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
648283704	615	32.98	36	602	16	567	1.0e-105	377	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
648283705	407	32.18	3	397	6	431	7.0e-73	267	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
648283710	353	42.12	21	350	1	320	1.0e-99	356	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
648283712	241	39.66	8	239	5	225	3.0e-35	142	COG1040	Predicted amidophosphoribosyltransferases	225
648283713	85	57.69	4	80	3	80	2.0e-22	97	COG0695	Glutaredoxin	80
648283714	146	24.19	16	139	1	123	2.0e-07	48.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
648283715	100	41.03	9	82	2	79	3.0e-12	63.4	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
648283716	250	52.05	2	245	9	243	1.0e-81	296	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
648283717	332	22.41	29	321	7	282	2.0e-17	83.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648283718	515	29.16	1	491	4	534	1.0e-67	251	COG0747	ABC-type transport system, periplasmic component	556
648283719	225	53.36	1	221	1	221	2.0e-75	275	COG3822	D-lyxose ketol-isomerase	225
648283720	436	62.64	1	436	1	444	0.0e+00	636	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
648283721	185	64.04	9	185	2	177	1.0e-67	249	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
648283724	1125	27.97	7	1102	5	1130	0.0e+00	506	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
648283725	976	32.39	8	694	1	697	5.0e-76	280	COG3893	Inactivated superfamily I helicase	697
648283727	325	31.86	5	303	2	338	2.0e-38	153	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
648283728	157	41.61	8	155	3	149	5.0e-34	137	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
648283730	463	19.83	93	448	1	336	1.0e-18	87.9	COG0642	Signal transduction histidine kinase	336
648283731	206	36.18	1	196	5	197	2.0e-35	142	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
648283732	184	69.23	4	184	1	182	5.0e-65	240	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
648283733	161	27.27	1	161	2	164	3.0e-09	54.9	COG1247	L-amino acid N-acyltransferase YncA	169
648283734	188	27.96	5	186	1	186	1.0e-21	96.2	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
648283736	461	55.04	1	453	1	420	0.0e+00	627	COG0499	S-adenosylhomocysteine hydrolase	420
648283737	322	27.9	1	309	1	307	2.0e-33	136	COG1893	Ketopantoate reductase	307
648283738	449	37.8	30	436	11	391	2.0e-73	269	COG4222	Uncharacterized conserved protein	391
648283739	666	20.39	76	666	72	699	5.0e-21	96.6	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
648283744	409	26.33	106	398	1	292	5.0e-24	106	COG4974	Site-specific recombinase XerD	300
648283749	533	43.02	1	530	4	535	6.0e-127	448	COG2303	Choline dehydrogenase or related flavoprotein	542
648283750	281	41.67	4	252	2	252	5.0e-59	221	COG0169	Shikimate 5-dehydrogenase	283
648283752	267	45.7	20	265	4	251	2.0e-39	156	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648283753	234	57.45	1	234	3	237	3.0e-90	324	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
648283754	599	44.8	358	594	4	250	2.0e-71	264	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
648283755	295	42.12	1	287	3	293	3.0e-50	192	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
648283756	398	30.32	14	385	1	361	2.0e-46	179	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648283757	576	39.02	11	575	2	548	8.0e-121	427	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
648283758	333	44.07	6	329	2	326	5.0e-76	278	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
648283759	351	37.92	1	343	1	350	4.0e-53	202	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
648283760	226	33.18	1	222	1	222	3.0e-34	138	COG1802	DNA-binding transcriptional regulator, GntR family	230
648283761	437	22	1	432	7	433	4.0e-39	155	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648283762	293	37.8	2	290	1	290	1.0e-55	210	COG1175	ABC-type sugar transport system, permease component	295
648283763	278	39.35	1	274	3	276	2.0e-53	202	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648283765	350	55.07	1	345	1	338	2.0e-124	438	COG3839	ABC-type sugar transport system, ATPase component	338
648283766	314	41.8	3	312	13	323	6.0e-73	267	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
648283767	416	29.19	28	404	1	387	8.0e-48	185	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648283768	93	47.78	1	90	2	90	2.0e-22	97.3	COG4311	Sarcosine oxidase delta subunit	97
648283769	980	38.79	586	980	1	379	1.0e-95	344	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
648283770	186	26.9	15	181	17	185	2.0e-13	69.2	COG4583	Sarcosine oxidase gamma subunit	189
648283774	335	23.5	79	269	64	247	3.0e-07	49.9	COG1240	Mg-chelatase subunit ChlD	261
648283777	334	43.33	10	334	12	328	2.0e-63	236	COG0714	MoxR-like ATPase	329
648283779	526	33.68	22	468	2	460	4.0e-73	269	COG3119	Arylsulfatase A or related enzyme	475
648283782	434	21.31	106	408	1	246	7.0e-27	115	COG1192	Cellulose biosynthesis protein BcsQ	259
648283784	434	44.2	1	434	3	458	1.0e-113	403	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
648283785	597	38.28	10	588	2	603	9.0e-113	401	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
648283787	698	42.82	11	698	5	641	0.0e+00	493	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
648283788	315	41.38	2	315	1	319	5.0e-75	274	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
648283789	382	33.54	40	355	5	315	5.0e-39	155	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
648283790	427	37.3	3	418	14	445	3.0e-103	369	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
648283791	235	32.58	16	235	10	229	4.0e-31	128	COG1802	DNA-binding transcriptional regulator, GntR family	230
648283792	593	19.32	122	592	54	456	4.0e-22	99	COG0471	Di- and tricarboxylate transporter	461
648283793	344	44.62	30	344	1	312	2.0e-99	356	COG3958	Transketolase, C-terminal subunit	312
648283794	282	47.54	4	247	1	243	3.0e-86	311	COG3959	Transketolase, N-terminal subunit	243
648283795	580	50.91	8	334	2	322	5.0e-90	325	COG2376	Dihydroxyacetone kinase	323
648283796	270	21.94	14	243	34	256	4.0e-08	52.1	COG1082	Sugar phosphate isomerase/epimerase	274
648283797	253	41.73	6	249	3	249	5.0e-45	174	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648283798	322	38.2	2	322	6	327	1.0e-73	270	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648283799	185	24.84	14	174	3	159	3.0e-14	71.5	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648283800	418	47.33	45	418	1	373	2.0e-82	299	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648283801	329	25	5	301	1	297	2.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
648283802	158	42.86	7	138	13	142	5.0e-28	117	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
648283803	668	57.1	19	667	8	663	0.0e+00	887	COG0021	Transketolase	663
648283804	261	43.82	1	247	1	247	6.0e-74	270	COG0149	Triosephosphate isomerase	251
648283805	153	42.11	1	152	1	151	2.0e-35	141	COG0698	Ribose 5-phosphate isomerase RpiB	151
648283806	322	38.03	27	322	25	326	9.0e-73	267	COG0158	Fructose-1,6-bisphosphatase	326
648283807	344	43.94	1	329	1	286	3.0e-95	342	COG0191	Fructose/tagatose bisphosphate aldolase	286
648283809	88	50	1	88	1	84	5.0e-23	99.2	COG4115	Toxin component of the Txe-Axe toxin-antitoxin module, Txe/YoeB family	84
648283810	89	34.52	1	82	3	86	2.0e-08	51.2	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
648283811	316	34.73	1	308	9	317	6.0e-44	171	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
648283812	344	45.32	15	344	1	315	2.0e-55	209	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
648283813	513	45.63	9	507	1	497	0.0e+00	540	COG1129	ABC-type sugar transport system, ATPase component	500
648283814	213	30.2	21	213	13	204	5.0e-26	110	COG5618	Predicted periplasmic lipoprotein	206
648283815	535	33.46	5	512	4	502	1.0e-84	307	COG1070	Sugar (pentulose or hexulose) kinase	502
648283816	502	48.24	1	500	8	514	0.0e+00	525	COG0578	Glycerol-3-phosphate dehydrogenase	532
648283818	311	44.73	1	310	7	317	2.0e-78	285	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
648283819	255	34.78	1	252	1	252	2.0e-52	199	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
648283820	486	42.89	14	480	6	472	2.0e-116	412	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
648283821	404	48.49	1	398	1	357	2.0e-123	435	COG1312	D-mannonate dehydratase	362
648283822	232	31.74	1	228	1	230	8.0e-35	140	COG1802	DNA-binding transcriptional regulator, GntR family	230
648283823	325	39.29	4	307	1	307	6.0e-72	264	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648283824	166	25	1	148	5	152	3.0e-12	65	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648283825	425	50	46	423	1	378	6.0e-93	334	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648283826	349	37.01	4	349	3	350	5.0e-66	244	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
648283827	678	37.66	2	678	1	699	0.0e+00	553	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
648283828	387	29.89	107	371	10	284	8.0e-28	118	COG1408	Predicted phosphohydrolase, MPP superfamily	284
648283829	381	27.68	15	381	12	409	6.0e-34	138	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648283830	262	32	15	260	1	245	2.0e-36	146	COG1414	DNA-binding transcriptional regulator, IclR family	246
648283831	337	29.78	6	321	3	300	7.0e-41	161	COG1893	Ketopantoate reductase	307
648283833	271	35.29	14	258	2	251	1.0e-35	143	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648283834	346	22.75	7	341	12	358	8.0e-31	128	COG0687	Spermidine/putrescine-binding periplasmic protein	363
648283835	352	47.61	1	352	3	351	6.0e-110	390	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
648283836	257	42.06	2	253	13	264	4.0e-48	184	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
648283837	305	39.3	20	304	1	285	1.0e-54	206	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
648283839	537	38.11	18	530	8	531	1.0e-115	410	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648283840	389	33.08	1	388	1	392	2.0e-64	240	COG0183	Acetyl-CoA acetyltransferase	392
648283841	267	34.15	12	257	1	244	6.0e-41	161	COG1414	DNA-binding transcriptional regulator, IclR family	246
648283842	333	43.03	4	329	6	330	5.0e-76	277	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648283843	162	24.84	1	161	8	166	2.0e-17	82.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648283844	442	43.78	54	439	1	376	3.0e-82	299	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648283845	254	42.91	8	242	6	250	2.0e-46	179	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648283846	421	34.12	4	415	9	425	3.0e-113	402	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
648283847	315	35.02	1	312	4	319	6.0e-52	198	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
648283848	216	33.82	11	214	18	205	2.0e-25	109	COG5618	Predicted periplasmic lipoprotein	206
648283849	515	48.01	5	504	4	500	0.0e+00	557	COG1129	ABC-type sugar transport system, ATPase component	500
648283850	355	42.6	16	345	2	316	2.0e-58	219	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
648283851	346	32.58	1	345	1	342	8.0e-48	184	COG0673	Predicted dehydrogenase	342
648283853	240	37.61	10	233	4	228	1.0e-40	159	COG2186	DNA-binding transcriptional regulator, FadR family	241
648283854	450	31.39	3	446	1	411	2.0e-59	223	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
648283856	428	19.84	52	420	31	393	3.0e-14	73.3	COG2814	Predicted arabinose efflux permease, MFS family	394
648283857	539	26.21	1	533	6	547	1.0e-66	247	COG0747	ABC-type transport system, periplasmic component	556
648283859	464	41.63	1	447	2	466	6.0e-106	378	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
648283860	314	41.27	1	314	1	315	1.0e-78	286	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648283861	270	43.98	2	266	20	285	9.0e-54	203	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648283862	360	50.48	20	330	2	266	3.0e-90	325	COG4608	ABC-type oligopeptide transport system, ATPase component	309
648283863	330	52.35	11	326	1	315	3.0e-112	398	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
648283864	309	31.1	6	299	4	297	1.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
648283865	442	31.11	55	442	2	375	9.0e-54	204	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648283866	187	23.36	31	164	13	145	6.0e-08	51	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
648283867	352	21.8	1	339	2	332	1.0e-28	120	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648283868	793	35.14	14	789	5	730	0.0e+00	512	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
648283869	166	52.63	8	158	1	152	9.0e-45	172	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
648283870	277	36.56	8	275	6	282	2.0e-45	176	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
648283871	231	22.8	14	205	5	194	6.0e-11	61.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648283872	253	43.19	1	251	1	251	9.0e-44	170	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648283873	271	29.18	6	265	4	282	1.0e-16	80.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648283875	436	40.32	6	436	9	447	3.0e-82	299	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
648283876	181	30.68	4	178	7	181	4.0e-22	98	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
648283877	351	30.86	4	336	12	344	7.0e-49	188	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
648283878	264	39.54	10	264	1	253	3.0e-46	178	COG1712	Predicted dinucleotide-utilizing enzyme	255
648283879	316	38.91	1	238	1	234	7.0e-50	191	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
648283881	240	33.33	13	240	1	226	8.0e-30	124	COG1802	DNA-binding transcriptional regulator, GntR family	230
648283883	413	58.82	3	410	1	406	0.0e+00	493	COG3748	Uncharacterized membrane protein	407
648283884	303	29.28	4	301	3	297	1.0e-33	137	COG0583	DNA-binding transcriptional regulator, LysR family	297
648283885	118	60.17	1	118	7	124	7.0e-43	165	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
648283886	463	59.63	297	457	10	167	6.0e-55	208	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
648283887	159	47.5	1	158	3	162	1.0e-45	175	COG3194	Ureidoglycolate hydrolase (allantoin degradation)	168
648283888	474	38.8	8	455	2	444	3.0e-81	295	COG2233	Xanthine/uracil permease	451
648283889	497	40.17	4	484	2	442	6.0e-95	341	COG2233	Xanthine/uracil permease	451
648283891	331	40.72	1	325	1	331	3.0e-81	295	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
648283892	321	37	1	321	4	329	4.0e-58	218	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
648283893	479	34.43	20	468	31	480	1.0e-77	284	COG1953	Cytosine/uracil/thiamine/allantoin permease	497
648283894	387	32.27	21	382	10	368	1.0e-56	214	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
648283895	321	40.62	4	318	2	321	3.0e-81	295	COG1171	Threonine dehydratase	347
648283896	395	37.98	1	386	2	383	1.0e-101	363	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
648283897	280	43.9	31	274	1	246	2.0e-54	205	COG1414	DNA-binding transcriptional regulator, IclR family	246
648283898	288	60.67	5	271	3	263	5.0e-110	390	COG3257	Uncharacterized protein, possibly involved in glyoxylate utilization	264
648283902	400	35.15	19	384	15	371	3.0e-76	279	COG3328	Transposase (or an inactivated derivative)	379
648283907	547	23.74	1	212	1	200	2.0e-18	87.9	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
648283915	305	26.67	7	305	1	295	5.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
648283917	412	20.66	159	399	86	292	7.0e-17	82	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
648283919	113	28.95	2	113	12	105	6.0e-14	69.2	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
648283920	121	33.04	1	112	15	126	8.0e-11	59.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
648283924	378	26.24	8	365	25	340	1.0e-37	150	COG0673	Predicted dehydrogenase	342
648283925	312	30.15	6	253	8	266	3.0e-40	158	COG1018	Ferredoxin-NADP reductase	266
648283926	380	41.44	7	379	1	351	1.0e-81	296	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
648283930	616	39.64	4	603	27	631	4.0e-106	379	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
648283931	302	27.21	2	302	29	320	2.0e-30	126	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
648283932	155	28.57	6	131	1	126	2.0e-09	55.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
648283933	344	35.71	17	335	4	320	1.0e-61	230	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
648283934	526	28.24	2	516	43	536	4.0e-47	182	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
648283935	283	48.39	7	283	1	277	3.0e-86	311	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
648283936	492	42.59	16	490	1	470	2.0e-118	419	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648283937	264	35.25	23	264	2	244	1.0e-47	183	COG1414	DNA-binding transcriptional regulator, IclR family	246
648283938	239	54.63	1	227	1	220	2.0e-71	262	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
648283939	231	50	6	228	1	224	1.0e-75	275	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
648283940	399	40.78	1	399	1	392	5.0e-88	318	COG0183	Acetyl-CoA acetyltransferase	392
648283959	381	29.32	100	363	3	254	9.0e-40	158	COG1192	Cellulose biosynthesis protein BcsQ	259
648283960	309	26.76	53	263	7	208	2.0e-11	63.4	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
648283962	723	25.37	13	210	4	186	1.0e-08	55.7	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
648283965	445	27.9	134	445	21	335	4.0e-26	112	COG0642	Signal transduction histidine kinase	336
648283966	219	42.79	1	219	1	228	3.0e-53	201	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648283967	105	22.09	20	105	1	81	2.0e-11	60.9	COG5591	Uncharacterized protein	103
648283968	461	30.94	75	460	43	437	3.0e-60	226	COG4097	Predicted ferric reductase	438
648283971	735	19.78	26	735	1	587	6.0e-48	186	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
648283972	326	40.58	1	300	16	321	5.0e-76	277	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
648283973	635	39.97	12	611	95	712	0.0e+00	462	COG2217	Cation transport ATPase	713
648283974	233	41.59	10	232	4	229	2.0e-27	115	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
648283975	134	32.28	1	123	2	122	2.0e-19	88.2	COG0629	Single-stranded DNA-binding protein	167
648283994	334	30.82	15	294	12	281	9.0e-43	167	COG4974	Site-specific recombinase XerD	300
648283996	343	25.27	70	336	60	317	6.0e-06	45.4	COG4643	Uncharacterized domain associated with phage/plasmid primase	366
648283998	90	39.13	17	85	5	68	6.0e-13	65.7	COG3831	WGR domain, predicted DNA-binding domain in MolR	85
648284003	370	25.97	3	362	3	345	1.0e-49	190	COG3177	Fic family protein	348
648284004	339	31.31	4	328	1	303	4.0e-36	145	COG3547	Transposase	303
648284006	239	24.34	8	239	4	257	8.0e-14	71	COG1192	Cellulose biosynthesis protein BcsQ	259
648284009	641	28.77	39	524	67	556	2.0e-76	280	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
648284010	283	30.29	87	282	10	217	1.0e-33	136	COG1230	Co/Zn/Cd efflux system component	296
648284011	116	40.66	14	103	10	100	6.0e-11	59.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
648284014	198	35.2	18	194	1	177	3.0e-33	135	COG1386	Chromosome segregation and condensation protein ScpB	184
648284016	361	26.2	48	344	21	281	1.0e-17	84.5	COG4974	Site-specific recombinase XerD	300
648284017	516	35.19	89	250	2	157	3.0e-23	103	COG3436	Transposase	157
648284023	318	26.63	33	228	1	191	1.0e-10	61.1	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
648284024	402	33.21	120	391	1	258	2.0e-50	193	COG1192	Cellulose biosynthesis protein BcsQ	259
648284026	233	40.87	9	216	5	211	5.0e-40	157	COG3316	Transposase (or an inactivated derivative)	215
648284027	522	22.52	17	277	10	262	2.0e-16	80.9	COG4584	Transposase	278
648284028	237	35.83	1	236	10	249	4.0e-41	161	COG1484	DNA replication protein DnaC	254
648284029	220	29.12	1	180	3	184	1.0e-17	83	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
648284032	157	25.44	35	146	8	110	2.0e-08	51.8	COG0607	Rhodanese-related sulfurtransferase	110
648284036	259	40.69	110	253	7	149	3.0e-24	105	COG3436	Transposase	157
648284039	240	40.77	5	235	1	228	1.0e-53	202	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648284040	488	29.53	183	461	41	333	2.0e-34	140	COG0642	Signal transduction histidine kinase	336
648284042	666	52.15	1	650	1	643	0.0e+00	620	COG1138	Cytochrome c biogenesis factor	648
648284043	188	21.37	32	159	2	127	2.0e-08	52.6	COG0526	Thiol-disulfide isomerase or thioredoxin	127
648284044	157	41.06	1	151	4	153	1.0e-35	142	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
648284045	383	27.24	1	287	2	285	1.0e-30	127	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
648284046	709	28.03	269	698	132	569	2.0e-67	250	COG4232	Thiol:disulfide interchange protein	569
648284050	197	26.28	1	137	2	135	4.0e-07	48.5	COG3909	Cytochrome c556	147
648284052	464	31.63	5	464	1	449	1.0e-68	254	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
648284053	160	21.15	2	156	13	145	6.0e-06	43.8	COG2010	Cytochrome c, mono- and diheme variants	150
648284054	210	32.7	10	207	34	244	3.0e-30	125	COG1651	Protein-disulfide isomerase	244
648284055	66	30.88	1	65	4	71	1.0e-07	48.1	COG2608	Copper chaperone CopZ	71
648284056	836	48.46	71	815	1	712	0.0e+00	706	COG2217	Cation transport ATPase	713
648284057	132	30	1	118	1	120	7.0e-20	89.4	COG0789	DNA-binding transcriptional regulator, MerR family	124
648284058	240	40	8	64	11	70	3.0e-10	58.8	COG0695	Glutaredoxin	80
648284061	420	31.72	4	420	25	449	2.0e-55	210	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
648284062	150	23.24	1	140	28	169	5.0e-12	63.9	COG1495	Disulfide bond formation protein DsbB	170
648284066	128	28.32	15	127	22	134	1.0e-16	79.2	COG3439	Uncharacterized conserved protein, DUF302 family	137
648284067	306	38.89	1	298	1	280	4.0e-54	205	COG0682	Prolipoprotein diacylglyceryltransferase	287
648284068	594	52.63	3	591	147	709	0.0e+00	663	COG2217	Cation transport ATPase	713
648284069	445	25.51	1	422	3	440	5.0e-15	76	COG0531	Amino acid transporter	466
648284071	240	37.85	5	217	13	219	4.0e-25	108	COG0785	Cytochrome c biogenesis protein CcdA	220
648284073	728	41.29	11	701	25	709	0.0e+00	589	COG2217	Cation transport ATPase	713
648284075	116	45.61	2	114	8	121	4.0e-23	99.6	COG1321	Mn-dependent transcriptional regulator, DtxR family	154
648284077	523	37.14	21	496	20	499	4.0e-85	308	COG0815	Apolipoprotein N-acyltransferase	518
648284078	157	43.24	9	152	14	160	2.0e-24	105	COG0597	Lipoprotein signal peptidase	167
648284079	260	44.57	1	260	1	265	3.0e-38	152	COG0428	Zinc transporter ZupT	266
648284080	152	44.3	1	148	1	146	1.0e-37	148	COG3019	Uncharacterized conserved protein	149
648284082	208	40.13	49	202	50	206	3.0e-36	145	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
648284083	146	37.24	2	146	7	150	1.0e-25	108	COG2847	Copper(I)-binding protein	151
648284086	188	43.9	24	185	39	201	2.0e-35	142	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
648284087	142	36.28	2	113	1	113	3.0e-19	87.5	COG0789	DNA-binding transcriptional regulator, MerR family	124
648284090	321	38.06	1	289	7	292	8.0e-58	217	COG1230	Co/Zn/Cd efflux system component	296
648284094	400	35.42	19	384	15	371	1.0e-76	280	COG3328	Transposase (or an inactivated derivative)	379
648284095	516	35.58	88	250	3	157	1.0e-22	101	COG3436	Transposase	157
648284100	666	55.39	1	666	1	644	0.0e+00	893	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
648284105	709	61.72	6	545	3	548	0.0e+00	724	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
648284107	159	42.33	1	159	2	164	3.0e-33	134	COG1247	L-amino acid N-acyltransferase YncA	169
648284108	227	25.86	51	221	1	173	3.0e-18	85.4	COG1076	DnaJ-domain-containing proteins 1	174
648284110	240	53.14	1	239	2	239	9.0e-78	283	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
648284111	128	33.33	3	128	42	162	2.0e-13	68.5	COG4731	Uncharacterized conserved protein, DUF2147 family	162
648284113	208	46.53	5	205	2	202	4.0e-57	214	COG0125	Thymidylate kinase	208
648284114	391	41.08	5	372	12	377	1.0e-90	326	COG1686	D-alanyl-D-alanine carboxypeptidase	389
648284121	1110	20.62	173	810	1	627	2.0e-66	248	COG1483	Predicted ATPase, AAA+ superfamily	774
648284128	407	47.62	24	401	14	375	6.0e-94	338	COG3328	Transposase (or an inactivated derivative)	379
648284134	205	38.61	2	201	45	246	6.0e-34	137	COG1414	DNA-binding transcriptional regulator, IclR family	246
648284135	528	28.63	9	501	19	526	7.0e-71	261	COG0747	ABC-type transport system, periplasmic component	556
648284137	537	38.35	3	534	15	537	1.0e-120	427	COG0405	Gamma-glutamyltranspeptidase	539
648284138	324	42.41	1	322	1	317	4.0e-79	288	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648284139	314	45.26	30	314	12	288	3.0e-68	252	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648284140	323	53.46	4	317	1	315	2.0e-119	422	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
648284141	353	42.63	22	339	2	266	4.0e-90	324	COG4608	ABC-type oligopeptide transport system, ATPase component	309
648284142	348	29.27	8	334	10	337	2.0e-34	140	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
648284144	409	21.5	85	388	14	303	1.0e-07	51.5	COG0582	Integrase	309
648284148	521	25.68	7	506	29	542	2.0e-35	143	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
648284149	669	19.17	38	659	26	701	6.0e-49	189	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
648284150	431	20.92	17	365	13	289	4.0e-09	56.1	COG1566	Multidrug resistance efflux pump	352
648284151	1769	16.79	924	1427	59	577	2.0e-08	56.7	COG5295	Autotransporter adhesin	715
648284152	233	36.75	3	232	16	249	1.0e-41	163	COG1484	DNA replication protein DnaC	254
648284159	277	24.07	35	266	14	252	1.0e-26	113	COG2116	Formate/nitrite transporter FocA, FNT family	265
648284160	286	43.12	3	275	2	269	5.0e-80	290	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
648284161	731	27.3	45	731	30	728	1.0e-81	298	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
648284162	148	55.03	1	147	4	152	3.0e-52	197	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
648284163	233	23.38	1	225	1	218	1.0e-15	76.9	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
648284164	131	35.43	1	125	6	131	4.0e-18	83.7	COG1917	Cupin domain protein related to quercetin dioxygenase	131
648284165	211	32.71	1	208	2	211	1.0e-32	133	COG2085	Predicted dinucleotide-binding enzyme	211
648284166	253	31.03	167	252	35	121	3.0e-14	72.4	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
648284167	298	29.15	5	297	2	290	4.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
648284168	334	38.72	29	298	59	355	1.0e-48	187	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
648284169	153	31.85	13	146	1	131	5.0e-15	74.1	COG1917	Cupin domain protein related to quercetin dioxygenase	131
648284171	248	47.56	3	247	2	245	2.0e-74	272	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
648284172	316	27.3	7	316	11	299	2.0e-27	116	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
648284173	296	29.1	1	293	1	297	4.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
648284174	335	41.08	1	314	1	312	5.0e-75	274	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
648284175	228	36.63	14	215	4	201	2.0e-44	172	COG0684	Regulator of RNase E activity RraA	210
648284176	318	34.78	1	318	1	318	3.0e-56	212	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
648284178	501	45.89	1	499	3	497	2.0e-130	459	COG3333	TctA family transporter	504
648284179	324	21.69	1	324	4	332	5.0e-35	141	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648284180	171	26.71	26	171	19	161	3.0e-12	65	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648284181	430	35.88	50	427	3	377	2.0e-66	246	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648284182	316	30.48	36	294	14	278	8.0e-30	124	COG3386	Sugar lactone lactonase YvrE	307
648284183	181	56.9	1	173	3	165	3.0e-61	227	COG0678	Peroxiredoxin	165
648284186	388	46.67	2	387	14	395	8.0e-97	347	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
648284187	507	47.01	1	501	3	497	6.0e-129	454	COG3333	TctA family transporter	504
648284189	327	34.89	8	327	3	318	1.0e-59	224	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
648284190	222	43.04	1	221	1	229	3.0e-51	195	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648284191	456	30.25	144	454	20	328	6.0e-32	132	COG0642	Signal transduction histidine kinase	336
648284192	333	20.39	42	325	2	296	7.0e-13	68.2	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
648284193	322	29.35	15	319	10	303	4.0e-37	148	COG4313	Uncharacterized conserved protein	304
648284194	266	45.85	11	266	3	278	3.0e-54	205	COG2301	Citrate lyase beta subunit	283
648284195	278	44.77	3	278	1	273	1.0e-72	266	COG3777	Hydroxyacyl-ACP dehydratase HTD2, hotdog domain	273
648284196	366	46.07	1	361	5	371	2.0e-94	339	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
648284197	387	38.85	1	387	1	393	1.0e-87	316	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648284198	306	37.4	7	251	3	246	1.0e-37	150	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648284199	258	25.51	11	249	1	242	4.0e-26	111	COG1414	DNA-binding transcriptional regulator, IclR family	246
648284200	384	44.36	3	384	6	392	3.0e-92	332	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648284201	139	30.95	10	135	12	136	7.0e-19	86.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
648284202	126	28.57	11	119	14	132	1.0e-09	55.7	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
648284203	384	27.53	7	369	1	383	1.0e-45	177	COG0183	Acetyl-CoA acetyltransferase	392
648284204	706	38.15	8	620	5	594	5.0e-107	382	COG1042	Acyl-CoA synthetase (NDP forming)	598
648284205	287	32.2	145	259	1	118	3.0e-12	66.3	COG2030	Acyl dehydratase	159
648284206	253	34.51	1	250	4	257	1.0e-39	156	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648284208	308	31.08	1	294	1	291	2.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
648284209	376	23.82	16	323	13	319	4.0e-20	93	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
648284210	657	36.06	29	656	14	642	1.0e-99	357	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
648284211	221	57.6	1	216	1	215	2.0e-66	245	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
648284212	211	52.38	1	209	3	211	1.0e-65	242	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
648284213	301	37.18	42	300	3	278	5.0e-40	158	COG2301	Citrate lyase beta subunit	283
648284214	321	31.82	5	319	4	332	5.0e-51	194	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
648284215	445	28.8	1	359	4	366	1.0e-43	171	COG2079	2-methylcitrate dehydratase PrpD	453
648284216	208	29.81	3	207	62	269	1.0e-47	182	COG1072	Panthothenate kinase	283
648284217	339	23.84	1	278	3	279	2.0e-24	106	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
648284218	266	46.59	4	252	3	244	4.0e-76	278	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
648284219	254	31.37	1	253	6	258	4.0e-35	141	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
648284221	153	40.98	31	151	15	136	5.0e-22	96.9	COG3011	Predicted thiol-disulfide oxidoreductase YuxK, DCC family	137
648284222	209	19.5	1	198	1	200	1.0e-06	47	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648284223	450	28.11	51	447	49	407	3.0e-50	193	COG2124	Cytochrome P450	411
648284224	626	34.73	28	569	4	535	3.0e-99	356	COG1574	Predicted amidohydrolase YtcJ	535
648284225	771	57.67	1	771	3	780	0.0e+00	956	COG2183	Transcriptional accessory protein Tex/SPT6	780
648284228	222	35.75	1	221	8	217	1.0e-41	163	COG0850	Septum formation inhibitor MinC	219
648284229	282	63.1	11	280	1	269	8.0e-113	399	COG2894	Septum formation inhibitor-activating ATPase MinD	272
648284230	96	47.78	1	90	1	88	2.0e-19	87.6	COG0851	Septum formation topological specificity factor MinE	88
648284231	343	34.47	22	339	15	333	2.0e-54	206	COG2855	Uncharacterized membrane protein YadS	334
648284232	592	32.51	2	563	1	533	8.0e-111	394	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
648284233	506	27.73	208	443	13	246	3.0e-25	110	COG5607	CHAD domain (function unknown)	283
648284234	247	30.2	1	247	2	254	6.0e-37	148	COG1192	Cellulose biosynthesis protein BcsQ	259
648284235	157	32.67	5	153	2	150	2.0e-16	78.4	COG2954	CYTH domain, found in class IV adenylate cyclase and various triphosphatases	156
648284236	340	47.16	1	335	1	331	2.0e-111	395	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
648284237	278	49.27	5	278	7	279	2.0e-84	305	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
648284238	306	40.33	1	293	3	302	2.0e-71	262	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
648284239	191	25	4	173	10	181	5.0e-07	47.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648284240	503	32.29	3	447	4	470	1.0e-77	284	COG3119	Arylsulfatase A or related enzyme	475
648284241	485	46.95	10	480	2	471	0.0e+00	486	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648284242	552	52.95	1	537	6	542	0.0e+00	508	COG2303	Choline dehydrogenase or related flavoprotein	542
648284243	520	27.22	1	315	30	363	5.0e-23	102	COG1680	CubicO group peptidase, beta-lactamase class C family	390
648284244	393	25.47	28	393	7	309	3.0e-16	79.9	COG0391	Archaeal 2-phospho-L-lactate transferase/Bacterial gluconeogenesis factor, CofD/UPF0052 family	323
648284248	212	25.37	3	197	1	198	4.0e-21	94.9	COG0625	Glutathione S-transferase	211
648284249	403	36.9	1	403	1	392	2.0e-68	252	COG0183	Acetyl-CoA acetyltransferase	392
648284250	733	41.12	325	626	2	304	7.0e-80	292	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
648284251	90	33.73	2	82	8	90	1.0e-08	51.5	COG1359	Quinol monooxygenase YgiN	100
648284252	213	36.15	2	211	10	222	4.0e-32	131	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
648284253	261	36.86	1	255	1	246	3.0e-63	235	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
648284254	214	48	15	213	10	208	2.0e-58	218	COG2518	Protein-L-isoaspartate O-methyltransferase	209
648284255	410	24.81	172	410	1	262	2.0e-18	87.5	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
648284256	279	55.8	5	279	12	285	7.0e-101	360	COG2607	Predicted ATPase, AAA+ superfamily	287
648284257	333	37.8	7	297	1	252	8.0e-54	204	COG0805	Sec-independent protein secretion pathway component TatC	255
648284258	160	25.77	1	97	1	94	3.0e-09	54.6	COG1826	Sec-independent protein translocase protein TatA	94
648284259	72	35.82	5	71	4	70	3.0e-07	46.9	COG1826	Sec-independent protein translocase protein TatA	94
648284261	390	29.95	7	365	6	367	1.0e-28	120	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
648284262	190	43.68	2	190	3	192	2.0e-40	158	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
648284263	118	44.55	4	113	3	112	1.0e-26	111	COG0360	Ribosomal protein S6	112
648284264	75	70.15	4	70	9	75	9.0e-20	88.4	COG0238	Ribosomal protein S18	75
648284265	206	44.9	1	147	1	147	8.0e-41	160	COG0359	Ribosomal protein L9	148
648284267	443	41.59	1	433	1	436	2.0e-80	292	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
648284270	370	50.28	4	365	3	356	5.0e-115	408	COG0337	3-dehydroquinate synthetase	360
648284271	192	41.32	15	181	3	168	3.0e-47	181	COG0703	Shikimate kinase	172
648284276	444	46.84	15	441	2	418	0.0e+00	467	COG4536	Mg2+ and Co2+ transporter CorB, contains DUF21, CBS pair, and CorC-HlyC domains	423
648284277	394	29.25	150	358	1	206	1.0e-25	110	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
648284278	186	36.16	3	177	20	192	5.0e-25	107	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
648284279	423	61.76	1	420	3	422	0.0e+00	525	COG2379	Glycerate-2-kinase	422
648284280	560	24.35	26	453	41	489	2.0e-31	130	COG1042	Acyl-CoA synthetase (NDP forming)	598
648284282	238	47.39	29	238	1	203	3.0e-58	218	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
648284283	302	29.62	16	289	23	284	6.0e-33	134	COG0714	MoxR-like ATPase	329
648284291	256	25.97	17	256	31	288	2.0e-16	79.6	COG3176	Putative hemolysin	292
648284292	139	28.36	1	127	14	146	2.0e-12	65	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
648284293	193	23.75	24	176	25	173	9.0e-09	53.8	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
648284294	68	55.36	1	56	1	56	9.0e-18	81.8	COG0333	Ribosomal protein L32	57
648284295	370	43.75	14	347	2	333	4.0e-95	342	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
648284296	323	59.63	2	323	1	322	5.0e-112	397	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
648284297	92	43.02	2	87	6	91	6.0e-24	102	COG0776	Bacterial nucleoid DNA-binding protein	94
648284298	370	31.63	10	106	2	98	5.0e-14	72.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
648284300	358	27.44	194	357	31	181	4.0e-26	112	COG0717	Deoxycytidine triphosphate deaminase	183
648284301	443	25.95	265	440	1	181	3.0e-07	50.1	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
648284302	256	46.86	54	224	6	179	9.0e-41	160	COG1386	Chromosome segregation and condensation protein ScpB	184
648284303	268	33.73	22	268	2	246	5.0e-38	151	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
648284304	335	37.26	7	314	6	314	8.0e-55	207	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
648284306	580	37.7	1	579	1	577	0.0e+00	513	COG0018	Arginyl-tRNA synthetase	577
648284307	618	27.12	15	421	11	428	2.0e-45	177	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
648284308	390	44.8	1	384	9	412	2.0e-102	366	COG0232	dGTP triphosphohydrolase	412
648284309	107	46.79	1	106	1	109	2.0e-28	117	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
648284310	507	37.05	23	494	10	471	2.0e-107	383	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648284311	318	44.97	1	316	1	316	9.0e-78	283	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
648284312	161	34.44	1	151	1	150	6.0e-28	117	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648284313	485	46.34	25	485	11	470	0.0e+00	460	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648284314	456	42.45	3	456	1	446	0.0e+00	505	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
648284315	376	26.49	84	376	88	379	3.0e-29	123	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648284316	379	42.78	1	377	1	387	1.0e-82	300	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648284317	343	30.08	1	229	4	235	2.0e-31	130	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648284318	290	46.6	1	285	1	286	5.0e-69	254	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
648284319	217	30.56	3	207	1	214	2.0e-20	93	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
648284320	211	45.19	1	206	5	212	1.0e-52	199	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
648284321	402	23.66	12	398	14	394	1.0e-15	77.9	COG2814	Predicted arabinose efflux permease, MFS family	394
648284322	516	29.58	173	502	54	408	4.0e-36	146	COG0840	Methyl-accepting chemotaxis protein	408
648284325	405	32.14	1	398	14	406	1.0e-120	426	COG0538	Isocitrate dehydrogenase	407
648284327	206	31.07	1	203	1	205	3.0e-30	124	COG1284	Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains	289
648284328	297	42.86	5	297	7	324	8.0e-70	257	COG3588	Fructose-bisphosphate aldolase class 1	332
648284329	451	25.99	1	451	3	410	2.0e-47	183	COG2124	Cytochrome P450	411
648284331	250	50	12	228	10	220	9.0e-28	117	COG0785	Cytochrome c biogenesis protein CcdA	220
648284332	985	46.7	260	667	77	485	3.0e-111	396	COG1530	Ribonuclease G or E	487
648284333	141	36.69	6	141	10	143	4.0e-22	97.3	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
648284334	289	46.15	2	286	1	286	2.0e-79	289	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
648284335	822	31.1	10	807	3	757	3.0e-102	366	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
648284338	417	47.53	14	398	12	391	6.0e-105	374	COG2262	50S ribosomal subunit-associated GTPase HflX	411
648284339	79	64.29	6	75	5	74	3.0e-27	113	COG1923	sRNA-binding regulator protein Hfq	77
648284340	504	27.15	1	504	1	488	6.0e-38	152	COG0168	Trk-type K+ transport system, membrane component	499
648284341	458	33.48	1	229	1	223	4.0e-41	162	COG0569	Trk K+ transport system, NAD-binding component	225
648284343	472	42.98	1	450	4	456	0.0e+00	462	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
648284344	740	40.33	5	723	10	712	0.0e+00	539	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
648284345	457	35.95	1	455	3	463	1.0e-98	354	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
648284346	361	39.6	7	354	10	356	1.0e-83	303	COG3852	Signal transduction histidine kinase, nitrogen specific	363
648284347	327	40.37	6	324	5	323	4.0e-78	285	COG0042	tRNA-dihydrouridine synthase	323
648284348	378	55.77	222	377	1	156	1.0e-56	214	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
648284349	161	38.16	1	149	17	156	3.0e-21	94.6	COG1267	Phosphatidylglycerophosphatase A	160
648284350	159	55.48	5	158	9	162	5.0e-41	160	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
648284351	151	45.27	1	148	1	144	1.0e-39	155	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
648284352	180	52.27	1	176	1	175	9.0e-60	222	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
648284354	152	32.41	7	151	8	147	5.0e-14	70.4	COG3909	Cytochrome c556	147
648284355	299	24.65	153	292	17	150	1.0e-07	50.7	COG2010	Cytochrome c, mono- and diheme variants	150
648284356	487	46.06	1	469	2	444	0.0e+00	531	COG1160	Predicted GTPases	444
648284357	443	22.35	56	397	12	355	4.0e-21	96.1	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
648284358	218	30.62	5	208	4	211	6.0e-15	74.7	COG4649	Uncharacterized protein	221
648284360	1236	22.5	3	1163	1	1005	0.0e+00	516	COG0841	Multidrug efflux pump subunit AcrB	1009
648284361	378	33.53	113	276	2	164	7.0e-27	115	COG4335	3-methyladenine DNA glycosylase AlkC	167
648284362	259	32.06	3	255	1	251	5.0e-30	124	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648284366	543	53.44	18	540	4	527	0.0e+00	731	COG4108	Peptide chain release factor RF-3	528
648284367	141	29.75	1	120	1	121	2.0e-19	87.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
648284368	133	45.37	26	131	18	124	2.0e-16	78.5	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
648284370	416	44.56	13	403	9	392	9.0e-87	314	COG3552	Uncharacterized conserved protein, contains von Willebrand factor type A (vWA) domain	395
648284372	937	34.78	21	875	24	914	0.0e+00	600	COG1391	Glutamine synthetase adenylyltransferase	963
648284373	155	29.05	10	153	6	152	1.0e-13	69.5	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
648284374	354	35.71	1	221	1	224	4.0e-26	112	COG1994	Zn-dependent protease (includes SpoIVFB)	230
648284376	455	39.01	136	433	86	408	6.0e-44	172	COG0840	Methyl-accepting chemotaxis protein	408
648284377	332	26.69	9	319	2	325	8.0e-40	158	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
648284378	262	36.3	1	262	1	280	2.0e-46	179	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
648284381	161	52.94	1	153	1	153	8.0e-57	212	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
648284382	177	43.15	1	145	1	143	2.0e-28	118	COG3427	Carbon monoxide dehydrogenase subunit G	146
648284384	334	46.85	4	334	2	322	1.0e-102	366	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
648284388	394	63.04	1	394	1	392	0.0e+00	549	COG3825	Uncharacterized conserved protein,  contains von Willebrand factor type A (vWA) domain	393
648284389	281	33.8	1	274	6	289	6.0e-36	144	COG2971	BadF-type ATPase, related to human N-acetylglucosamine kinase	301
648284390	217	21.7	6	209	1	211	4.0e-19	88.3	COG0625	Glutathione S-transferase	211
648284391	380	52.75	16	376	41	404	5.0e-128	451	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
648284393	144	31.62	1	112	6	122	8.0e-16	76.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
648284396	141	35.62	56	120	4	75	2.0e-06	44.7	COG0776	Bacterial nucleoid DNA-binding protein	94
648284397	232	33.18	4	216	2	212	5.0e-35	141	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
648284398	315	37.89	1	314	3	318	4.0e-75	274	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
648284399	426	23.22	1	415	18	424	2.0e-37	150	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648284400	400	35.42	19	384	15	371	1.0e-76	280	COG3328	Transposase (or an inactivated derivative)	379
648284401	240	19.18	3	240	57	297	1.0e-12	66.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
648284402	516	33.53	4	487	21	522	3.0e-83	302	COG0747	ABC-type transport system, periplasmic component	556
648284403	293	38.64	1	293	3	296	2.0e-58	218	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
648284404	321	49.36	4	316	2	311	5.0e-91	327	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
648284405	323	45.02	4	309	3	310	9.0e-77	280	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
648284406	323	46.44	1	322	1	317	1.0e-84	306	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648284407	312	46.18	25	312	9	288	1.0e-70	260	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648284408	607	53.83	1	561	1	539	0.0e+00	693	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
648284409	296	35.62	1	290	1	306	3.0e-36	145	COG0524	Sugar or nucleoside kinase, ribokinase family	311
648284410	316	23.73	5	303	1	292	9.0e-19	88	COG4974	Site-specific recombinase XerD	300
648284415	530	24.37	6	504	159	665	1.0e-47	184	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
648284416	690	23.21	97	683	78	693	3.0e-54	207	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
648284426	693	33.53	40	693	9	654	4.0e-124	438	COG3590	Predicted metalloendopeptidase	654
648284431	352	32.9	16	313	15	304	3.0e-32	132	COG2603	tRNA 2-selenouridine synthase SelU, contains rhodanese domain	334
648284432	720	27.58	7	370	1	385	6.0e-50	193	COG1252	NADH dehydrogenase, FAD-containing subunit	405
648284433	246	36.28	11	236	1	223	9.0e-39	153	COG2049	Allophanate hydrolase subunit 1	223
648284434	337	34.82	5	308	1	311	5.0e-60	225	COG1984	Allophanate hydrolase subunit 2	314
648284435	258	50.81	1	248	1	248	1.0e-79	289	COG1540	Lactam utilization protein B (function unknown)	252
648284436	246	63.9	1	240	1	241	2.0e-98	351	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
648284438	246	21.4	3	216	1	213	6.0e-13	68.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648284439	198	27.54	1	195	2	207	4.0e-15	74.9	COG0406	Broad specificity phosphatase PhoE	208
648284441	236	21.8	40	232	73	282	2.0e-11	62.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648284442	55	46.81	7	53	4	50	6.0e-08	49.1	COG0267	Ribosomal protein L33	50
648284443	384	36.31	38	383	91	455	6.0e-90	324	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
648284444	185	23.44	1	180	49	257	2.0e-16	78.9	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
648284445	220	41.44	1	218	24	228	7.0e-27	113	COG0670	Integral membrane protein, interacts with FtsH	233
648284447	290	26.42	4	284	1	297	2.0e-26	112	COG0583	DNA-binding transcriptional regulator, LysR family	297
648284448	278	43.11	1	276	46	326	2.0e-53	202	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
648284449	127	19.66	8	123	1	116	1.0e-07	48.5	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
648284450	269	35.5	13	268	2	260	1.0e-47	183	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
648284451	446	35.66	1	421	1	411	6.0e-68	251	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
648284452	158	35.57	1	148	46	191	7.0e-19	86.8	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
648284453	186	22.51	1	183	19	205	2.0e-14	72.1	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
648284454	445	31.27	46	443	21	405	2.0e-71	263	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
648284455	465	39.82	25	465	7	448	5.0e-105	374	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
648284456	188	37.77	10	186	5	189	4.0e-28	117	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
648284457	161	35.37	9	155	8	153	3.0e-30	124	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
648284458	420	54.48	1	420	1	423	0.0e+00	526	COG0151	Phosphoribosylamine-glycine ligase	428
648284459	510	44.06	9	468	1	429	3.0e-128	452	COG1570	Exonuclease VII, large subunit	440
648284464	462	48.33	136	458	15	340	5.0e-101	361	COG0552	Signal recognition particle GTPase	340
648284466	200	32.63	10	198	1	177	4.0e-29	121	COG2917	Intracellular septation protein A	180
648284467	433	19.44	73	433	71	440	7.0e-06	45.6	COG2271	Sugar phosphate permease	448
648284468	727	32.72	2	489	37	513	9.0e-93	335	COG0513	Superfamily II DNA and RNA helicase	513
648284469	309	30.74	1	308	2	307	8.0e-33	134	COG0679	Predicted permease	311
648284470	266	31.5	1	263	1	262	6.0e-43	167	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
648284471	268	46.06	6	257	3	254	2.0e-74	272	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
648284472	249	41.94	2	239	1	248	5.0e-59	221	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
648284473	325	44.85	1	325	5	333	2.0e-44	173	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
648284474	263	25.76	1	219	41	268	4.0e-20	91.9	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
648284475	620	25.2	12	620	9	608	8.0e-66	245	COG4206	Outer membrane cobalamin receptor protein	608
648284476	149	31.06	1	132	16	137	3.0e-18	84.5	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
648284477	330	48.73	7	311	1	314	4.0e-101	361	COG0275	16S rRNA C1402 N4-methylase RsmH	314
648284479	596	32.18	36	582	1	597	1.0e-102	367	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
648284480	494	40.67	21	489	8	475	8.0e-107	381	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
648284481	477	39.36	3	468	2	451	6.0e-102	365	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
648284482	360	45.4	19	360	1	316	8.0e-57	214	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
648284483	467	39.28	3	463	1	445	2.0e-105	376	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
648284485	408	47.45	13	406	2	408	2.0e-120	426	COG2081	Predicted flavoprotein YhiN	408
648284486	386	34.41	14	373	5	373	1.0e-61	230	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
648284487	377	39	10	364	3	355	3.0e-71	262	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
648284488	478	51.73	17	475	2	458	0.0e+00	560	COG0773	UDP-N-acetylmuramate-alanine ligase	459
648284490	359	35.67	1	356	8	315	9.0e-67	247	COG4531	ABC-type Zn2+ transport system, periplasmic component/surface adhesin	318
648284491	163	38.57	20	159	2	140	8.0e-28	116	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
648284492	259	41.34	1	235	2	254	2.0e-66	245	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
648284493	262	42.59	1	262	9	271	2.0e-37	149	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
648284497	155	50.39	14	142	23	150	2.0e-28	118	COG5321	Uncharacterized protein	164
648284499	249	33.15	71	245	58	235	1.0e-22	100	COG3904	Predicted periplasmic protein	245
648284502	348	29.25	2	331	47	371	1.0e-20	94.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
648284503	1037	49.17	1	1026	2	1009	0.0e+00	918	COG0841	Multidrug efflux pump subunit AcrB	1009
648284505	377	32.46	1	369	75	455	1.0e-35	144	COG1538	Outer membrane protein TolC	457
648284508	600	66.72	1	600	3	602	0.0e+00	1030	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
648284511	437	40.7	27	423	28	421	6.0e-101	361	COG0141	Histidinol dehydrogenase	425
648284512	320	28.15	5	273	2	268	2.0e-22	100	COG0583	DNA-binding transcriptional regulator, LysR family	297
648284513	254	28.47	1	252	9	281	2.0e-20	92.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648284516	156	40.16	35	156	3	124	2.0e-27	114	COG5349	Uncharacterized conserved protein, DUF983 family	126
648284517	159	45.33	9	157	32	181	1.0e-35	142	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
648284518	300	32.57	1	298	1	297	5.0e-35	141	COG0583	DNA-binding transcriptional regulator, LysR family	297
648284519	222	23.85	42	152	24	153	6.0e-06	44.5	COG5126	Ca2+-binding protein, EF-hand superfamily	160
648284520	194	42.31	10	188	1	181	2.0e-25	109	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
648284523	470	33.18	18	457	4	435	1.0e-62	234	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
648284525	232	28.44	6	229	5	217	2.0e-24	105	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
648284527	318	46.7	136	313	3	181	6.0e-37	148	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
648284531	392	28.95	16	166	15	158	1.0e-14	74.7	COG3666	Transposase	161
648284536	115	23.97	2	115	1	118	1.0e-10	58.6	COG3293	Transposase	124
648284537	543	26.67	1	461	5	418	1.0e-51	197	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
648284540	432	26.11	70	423	52	400	2.0e-25	110	COG2124	Cytochrome P450	411
648284545	161	36.45	46	148	20	126	6.0e-08	50.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
648284546	355	21.74	1	348	5	366	1.0e-17	84.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
648284547	1016	26.95	4	1003	2	1009	0.0e+00	637	COG0841	Multidrug efflux pump subunit AcrB	1009
648284548	397	25.32	8	392	12	394	9.0e-13	68.3	COG2814	Predicted arabinose efflux permease, MFS family	394
648284550	358	52	1	350	1	338	5.0e-123	434	COG3839	ABC-type sugar transport system, ATPase component	338
648284551	233	29.82	7	233	2	228	1.0e-25	110	COG1802	DNA-binding transcriptional regulator, GntR family	230
648284552	303	32.8	9	302	6	312	2.0e-35	143	COG0657	Acetyl esterase/lipase	312
648284553	404	25.65	1	400	6	424	9.0e-35	141	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648284554	307	42.27	14	304	1	289	4.0e-66	245	COG1175	ABC-type sugar transport system, permease component	295
648284555	277	37.88	19	276	18	281	2.0e-53	202	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648284556	295	27.61	5	257	1	257	3.0e-25	109	COG1082	Sugar phosphate isomerase/epimerase	274
648284557	331	22.03	1	331	3	334	9.0e-36	144	COG0673	Predicted dehydrogenase	342
648284558	301	41.58	5	294	16	297	4.0e-81	294	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
648284559	389	46.85	162	383	11	216	6.0e-47	181	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
648284560	311	53.72	1	307	1	309	1.0e-110	392	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
648284561	246	47.75	23	244	1	220	3.0e-45	175	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
648284563	343	46.03	16	329	14	288	9.0e-78	283	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
648284564	298	38.91	7	295	60	341	9.0e-66	244	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
648284565	323	29	5	323	4	334	1.0e-45	177	COG0673	Predicted dehydrogenase	342
648284566	186	37.11	1	184	3	193	8.0e-27	113	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
648284567	403	28.83	12	392	12	372	2.0e-51	196	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
648284568	433	27.34	33	413	1	387	5.0e-51	195	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648284569	453	37.09	8	452	1	443	4.0e-102	365	COG0174	Glutamine synthetase	443
648284570	226	36.22	12	195	3	197	1.0e-33	136	COG0518	GMP synthase - Glutamine amidotransferase domain	198
648284571	447	37.25	3	446	4	443	3.0e-104	372	COG0174	Glutamine synthetase	443
648284573	268	33.03	35	252	12	226	3.0e-35	142	COG4160	ABC-type arginine/histidine transport system, permease component	228
648284574	293	29.02	28	282	10	228	4.0e-33	135	COG4215	ABC-type arginine transport system, permease component	230
648284575	240	29.48	5	237	17	267	1.0e-26	113	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
648284576	258	60.08	3	254	2	254	3.0e-101	361	COG4598	ABC-type histidine transport system, ATPase component	256
648284577	146	35	1	140	6	145	2.0e-17	81.9	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
648284578	147	26.9	1	144	3	147	7.0e-10	56.5	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
648284581	261	44.27	2	249	1	253	4.0e-63	234	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
648284582	215	25.58	1	204	1	213	2.0e-16	79.2	COG4126	Asp/Glu/hydantoin racemase	230
648284583	396	31.15	192	374	52	230	1.0e-24	108	COG4126	Asp/Glu/hydantoin racemase	230
648284585	222	33.63	1	222	1	222	7.0e-33	134	COG1802	DNA-binding transcriptional regulator, GntR family	230
648284586	430	25.14	4	351	4	354	2.0e-34	140	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
648284587	465	38.61	6	463	11	467	1.0e-119	423	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648284588	329	37.99	9	327	3	306	2.0e-52	199	COG2017	Galactose mutarotase or related enzyme	308
648284589	282	38.44	1	280	14	307	2.0e-55	209	COG3386	Sugar lactone lactonase YvrE	307
648284590	502	29.29	6	491	2	467	6.0e-60	225	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648284591	309	31.54	5	299	1	292	2.0e-43	170	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
648284592	308	21.65	1	300	4	330	6.0e-23	101	COG0673	Predicted dehydrogenase	342
648284593	581	44.85	11	569	10	574	0.0e+00	644	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
648284594	397	50.38	8	397	8	394	1.0e-116	413	COG4214	ABC-type xylose transport system, permease component	394
648284595	517	51.09	1	503	5	497	0.0e+00	620	COG1129	ABC-type sugar transport system, ATPase component	500
648284596	353	45.64	10	353	8	338	1.0e-109	390	COG4213	ABC-type xylose transport system, periplasmic component	341
648284597	305	27.27	10	305	4	291	2.0e-24	106	COG0583	DNA-binding transcriptional regulator, LysR family	297
648284599	498	45.61	24	498	3	470	4.0e-119	422	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648284600	241	33.76	7	236	8	239	2.0e-36	146	COG2186	DNA-binding transcriptional regulator, FadR family	241
648284601	269	32.08	7	250	1	264	2.0e-34	139	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
648284602	223	50	16	221	14	221	2.0e-50	192	COG0765	ABC-type amino acid transport system, permease component	222
648284603	245	61.09	5	243	3	240	1.0e-105	375	COG1126	ABC-type polar amino acid transport system, ATPase component	240
648284604	415	31.83	4	403	8	403	2.0e-74	273	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
648284605	282	25.45	7	275	5	278	1.0e-32	133	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
648284606	515	31.85	3	512	21	553	2.0e-75	277	COG0747	ABC-type transport system, periplasmic component	556
648284607	306	48.26	1	306	1	316	2.0e-84	305	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648284608	298	50.71	21	298	10	289	2.0e-70	259	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648284609	579	54.96	7	549	3	539	0.0e+00	645	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
648284611	484	32.4	3	461	2	537	3.0e-81	296	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
648284618	349	27.42	1	294	1	302	9.0e-22	97.9	COG0644	Dehydrogenase (flavoprotein)	396
648284619	207	53.77	9	207	2	198	2.0e-68	252	COG2109	ATP:corrinoid adenosyltransferase	198
648284620	136	35.71	7	127	14	139	3.0e-23	100	COG5469	Predicted metal-binding protein	143
648284621	351	36.39	7	346	1	321	1.0e-72	267	COG0523	GTPase, G3E family	323
648284623	378	24.35	8	363	36	458	1.0e-36	147	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
648284624	209	49.28	4	209	3	207	1.0e-53	203	COG2082	Precorrin isomerase	210
648284625	246	42.92	8	246	2	234	2.0e-57	216	COG2243	Precorrin-2 methylase	234
648284626	248	50.4	1	247	1	242	9.0e-75	273	COG1010	Precorrin-3B methylase	249
648284627	249	44.02	1	225	2	234	4.0e-53	201	COG2099	Precorrin-6x reductase	257
648284628	403	47.19	227	400	6	183	1.0e-44	174	COG2242	Precorrin-6B methylase 2	187
648284630	262	54.58	1	249	3	252	3.0e-94	338	COG2875	Precorrin-4 methylase	254
648284631	436	47.14	2	429	1	435	0.0e+00	461	COG1797	Cobyrinic acid a,c-diamide synthase	451
648284632	245	44.87	1	234	2	231	8.0e-58	217	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
648284633	245	24.8	1	243	1	231	3.0e-23	101	COG2243	Precorrin-2 methylase	234
648284634	216	43.58	1	214	1	218	5.0e-56	210	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
648284635	260	29.91	27	257	16	248	1.0e-19	90.4	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
648284637	203	30.58	1	199	1	204	2.0e-14	72.2	COG0310	ABC-type Co2+ transport system, permease component	204
648284638	261	27.78	1	257	1	263	4.0e-37	148	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
648284639	642	18.74	67	642	91	768	9.0e-14	72.3	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
648284640	159	30.1	56	158	25	125	1.0e-07	49.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
648284641	439	28.23	42	409	4	380	6.0e-38	152	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
648284643	405	29.1	4	397	1	407	5.0e-55	208	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648284644	496	43.64	1	492	3	497	3.0e-117	415	COG3333	TctA family transporter	504
648284646	323	34.46	1	321	1	318	2.0e-49	189	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
648284647	303	28.57	2	299	1	297	2.0e-25	110	COG0583	DNA-binding transcriptional regulator, LysR family	297
648284648	226	34.43	5	215	15	224	6.0e-28	117	COG1802	DNA-binding transcriptional regulator, GntR family	230
648284650	414	46.9	45	414	1	371	5.0e-80	291	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648284651	155	32.47	1	154	7	160	3.0e-19	87.7	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648284652	322	34.95	1	321	1	328	6.0e-64	237	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648284653	230	25	30	224	4	203	1.0e-17	83.7	COG1335	Nicotinamidase-related amidase	205
648284654	201	33.67	1	198	30	226	5.0e-20	90.9	COG1802	DNA-binding transcriptional regulator, GntR family	230
648284655	570	36.59	102	568	2	475	1.0e-87	317	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
648284656	313	36.99	1	312	85	396	7.0e-58	217	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
648284658	319	35.53	3	317	1	317	6.0e-56	211	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
648284659	287	38.52	3	283	1	279	2.0e-52	199	COG2301	Citrate lyase beta subunit	283
648284661	505	51.79	3	503	1	500	0.0e+00	535	COG3333	TctA family transporter	504
648284663	429	29.41	25	385	1	366	1.0e-41	164	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648284664	258	43.97	4	255	2	250	2.0e-45	175	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648284665	318	29.01	1	290	1	288	3.0e-39	155	COG0451	Nucleoside-diphosphate-sugar epimerase	314
648284666	480	26.74	1	450	3	421	2.0e-41	164	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
648284667	433	37.37	54	432	3	378	1.0e-70	260	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648284670	644	35.62	4	376	13	386	5.0e-51	196	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
648284672	431	22.86	21	412	20	411	9.0e-09	55.2	COG3307	O-antigen ligase	424
648284676	328	25.64	3	328	23	371	4.0e-15	75.6	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
648284678	341	20.18	14	338	51	371	3.0e-15	76.5	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
648284680	351	25.71	1	332	12	358	3.0e-22	99.5	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
648284681	763	26.92	20	486	7	458	3.0e-48	187	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
648284682	417	21.12	1	411	20	423	1.0e-08	54.7	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
648284684	949	26.7	471	893	4	439	8.0e-13	70	COG2931	Ca2+-binding protein, RTX toxin-related	510
648284686	220	44.55	21	219	37	224	1.0e-55	209	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
648284688	404	30.64	6	161	27	197	7.0e-14	72.1	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
648284689	457	29.66	1	452	6	458	2.0e-63	236	COG1109	Phosphomannomutase	464
648284690	477	47.02	3	335	1	333	7.0e-106	378	COG0836	Mannose-1-phosphate guanylyltransferase	333
648284691	555	49.39	15	506	9	498	0.0e+00	518	COG1292	Choline-glycine betaine transporter	537
648284692	694	51.71	31	691	28	693	0.0e+00	739	COG1523	Pullulanase/glycogen debranching enzyme	697
648284694	741	35.45	108	739	133	772	3.0e-114	406	COG4993	Glucose dehydrogenase	773
648284696	313	30.26	6	302	3	303	2.0e-41	162	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
648284697	370	37.6	1	365	1	369	3.0e-82	298	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
648284699	734	60.19	5	733	4	739	0.0e+00	997	COG2838	Monomeric isocitrate dehydrogenase	744
648284700	264	25.98	1	252	25	275	1.0e-05	44.1	COG0842	ABC-type multidrug transport system, permease component	286
648284701	240	41.33	1	222	2	226	1.0e-55	209	COG1131	ABC-type multidrug transport system, ATPase component	293
648284702	267	31.89	15	267	3	255	8.0e-37	147	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
648284704	528	31.02	169	524	11	328	1.0e-30	128	COG0642	Signal transduction histidine kinase	336
648284705	226	39.04	7	223	3	229	6.0e-41	160	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648284706	157	45.52	5	149	13	157	1.0e-41	162	COG1607	Acyl-CoA hydrolase	157
648284707	334	27.23	69	270	13	217	3.0e-13	69.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648284708	270	47.22	6	147	8	148	1.0e-29	123	COG5501	Predicted secreted protein	148
648284711	749	27.71	260	589	1	326	2.0e-33	137	COG0642	Signal transduction histidine kinase	336
648284712	385	38.1	11	376	5	379	3.0e-68	252	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
648284713	241	35.12	15	219	2	203	5.0e-39	154	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
648284714	208	26.87	46	179	8	133	6.0e-15	74.3	COG3791	Uncharacterized conserved protein	133
648284718	326	24.02	49	274	1	221	6.0e-19	88.4	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
648284719	391	29.35	110	382	1	259	1.0e-43	170	COG1192	Cellulose biosynthesis protein BcsQ	259
648284720	369	31.78	5	338	16	347	1.0e-49	190	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
648284722	249	39.92	1	237	4	238	7.0e-57	214	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
648284723	298	21.14	1	296	4	266	3.0e-14	72.8	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
648284725	436	36.05	20	435	18	444	2.0e-98	352	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
648284726	333	28.48	23	325	22	315	7.0e-38	151	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
648284727	259	43.48	4	247	2	250	2.0e-45	176	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648284728	222	26.83	23	217	1	198	4.0e-25	107	COG1335	Nicotinamidase-related amidase	205
648284730	375	66.67	1	375	1	366	0.0e+00	549	COG1062	Zn-dependent alcohol dehydrogenase	366
648284731	274	35.18	1	274	7	313	4.0e-63	234	COG0627	S-formylglutathione hydrolase FrmB	316
648284732	127	48.76	7	127	13	132	1.0e-33	135	COG3474	Cytochrome c2	135
648284733	600	31.43	4	600	116	773	0.0e+00	552	COG4993	Glucose dehydrogenase	773
648284734	177	15.52	55	170	41	150	1.0e-05	43.4	COG2010	Cytochrome c, mono- and diheme variants	150
648284735	233	21.76	7	215	59	261	2.0e-09	56.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
648284737	269	24.39	16	138	23	144	2.0e-07	50.1	COG5501	Predicted secreted protein	148
648284741	381	21.82	38	344	30	350	1.0e-11	64.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648284742	323	27.04	21	315	44	343	1.0e-27	117	COG3391	DNA-binding beta-propeller fold protein YncE	381
648284744	321	19.05	1	308	6	312	7.0e-09	55.2	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
648284745	224	39.34	23	219	1	211	3.0e-51	195	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
648284747	788	27.73	467	783	1	316	9.0e-31	129	COG0668	Small-conductance mechanosensitive channel	316
648284748	241	45.98	3	226	2	225	1.0e-44	173	COG4662	ABC-type tungstate transport system, periplasmic component	227
648284749	255	36.89	41	236	19	224	9.0e-44	170	COG1131	ABC-type multidrug transport system, ATPase component	293
648284750	273	43.61	7	272	12	275	1.0e-76	279	COG2998	ABC-type tungstate transport system, permease component	280
648284751	292	30.04	73	290	1	221	6.0e-24	104	COG1910	Periplasmic molybdate-binding protein/domain	223
648284752	454	42.04	18	446	5	454	1.0e-109	390	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
648284755	404	28.28	157	398	2	215	1.0e-33	138	COG2864	Cytochrome b subunit of formate dehydrogenase	218
648284756	197	42.55	1	180	8	173	1.0e-36	146	COG0437	Fe-S-cluster-containing dehydrogenase component	203
648284757	971	31.29	5	648	1	615	5.0e-102	366	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
648284759	209	27.03	24	198	10	190	4.0e-20	91.6	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
648284764	354	42.31	93	322	43	265	3.0e-53	202	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
648284765	236	20.33	52	221	53	222	3.0e-07	49.1	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
648284768	87	36.84	13	87	2	77	3.0e-18	83.8	COG0425	TusA-related sulfurtransferase	78
648284769	720	42.64	320	717	7	404	3.0e-95	343	COG0303	Molybdopterin biosynthesis enzyme	404
648284770	163	46.01	1	159	2	161	6.0e-41	160	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
648284771	216	40.49	10	214	7	191	1.0e-39	156	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
648284772	287	32.82	9	265	4	264	2.0e-49	189	COG1526	Formate dehydrogenase assembly factor FdhD	266
648284774	183	34.48	9	181	5	178	2.0e-27	115	COG3038	Cytochrome b561	181
648284778	329	23.35	4	326	1	327	2.0e-22	99.9	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
648284779	265	49.01	9	259	4	247	3.0e-72	265	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
648284780	523	28.52	265	520	7	258	2.0e-26	114	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
648284781	345	27.43	72	345	91	377	1.0e-24	107	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648284782	121	41.38	1	115	2	117	2.0e-22	97.6	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
648284783	376	26.49	13	353	24	393	4.0e-71	262	COG0019	Diaminopimelate decarboxylase	394
648284784	417	42.22	2	400	1	377	2.0e-103	369	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
648284785	218	40	5	218	17	230	1.0e-30	126	COG1802	DNA-binding transcriptional regulator, GntR family	230
648284786	328	27.08	1	327	2	329	6.0e-42	164	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648284787	200	27.27	20	184	7	168	2.0e-19	89.2	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648284788	438	36.22	52	432	1	377	3.0e-75	275	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648284790	499	41.43	1	498	8	525	2.0e-114	406	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648284791	395	38.73	28	363	104	448	2.0e-82	300	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
648284792	460	26.92	123	456	1	329	3.0e-34	139	COG0642	Signal transduction histidine kinase	336
648284795	915	41.69	28	915	32	917	0.0e+00	757	COG0474	Magnesium-transporting ATPase (P-type)	917
648284796	1579	20.54	540	1579	174	1278	2.0e-63	238	COG2911	Autotransporter translocation and assembly factor TamB	1278
648284797	603	26.61	3	603	11	594	6.0e-72	265	COG0729	Outer membrane translocation and assembly module TamA	594
648284798	363	28.99	1	356	4	378	7.0e-31	128	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648284799	301	27.18	1	297	1	306	5.0e-32	131	COG0451	Nucleoside-diphosphate-sugar epimerase	314
648284800	588	41.89	8	492	3	482	4.0e-125	442	COG2812	DNA polymerase III, gamma/tau subunits	515
648284804	658	34.62	18	583	4	513	4.0e-107	382	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
648284805	319	41.94	14	292	1	253	5.0e-64	237	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
648284807	212	52.88	5	211	3	208	3.0e-66	244	COG4136	ABC-type uncharacterized transport system YnjBCD, ATPase component	213
648284808	560	39.6	12	558	10	550	1.0e-100	360	COG4135	ABC-type uncharacterized transport system YnjBCD, permease component	551
648284809	400	47.1	5	399	8	383	2.0e-86	313	COG4134	ABC-type uncharacterized transport system YnjBCD, periplasmic component	384
648284811	233	30.57	4	232	1	220	4.0e-23	101	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
648284812	225	34.72	7	219	6	220	3.0e-37	148	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
648284814	233	56.44	5	228	2	220	2.0e-83	302	COG0036	Pentose-5-phosphate-3-epimerase	220
648284816	139	39.81	1	108	6	111	9.0e-27	112	COG4451	Ribulose bisphosphate carboxylase small subunit	127
648284817	487	48.36	16	469	1	428	0.0e+00	539	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
648284818	359	42.73	1	329	1	286	2.0e-91	329	COG0191	Fructose/tagatose bisphosphate aldolase	286
648284819	402	47.62	1	395	2	390	2.0e-121	429	COG0126	3-phosphoglycerate kinase	395
648284820	333	59.34	2	330	1	331	4.0e-130	457	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
648284821	661	54.11	9	660	3	661	0.0e+00	887	COG0021	Transketolase	663
648284822	290	51.38	1	290	1	289	2.0e-114	405	COG3954	Phosphoribulokinase	289
648284823	335	44.95	14	316	19	322	3.0e-97	348	COG0158	Fructose-1,6-bisphosphatase	326
648284824	308	34.12	4	296	1	290	1.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
648284825	437	30.5	54	429	3	376	2.0e-60	226	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648284826	176	19.32	3	176	1	173	8.0e-08	50.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648284827	323	25.31	1	321	6	327	6.0e-37	148	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648284828	413	27.57	1	413	3	382	2.0e-35	143	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648284829	231	47.17	22	231	57	266	7.0e-66	243	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
648284830	280	23.26	12	267	10	213	2.0e-21	96.9	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
648284831	415	56.45	4	414	7	417	0.0e+00	583	COG4806	L-rhamnose isomerase	419
648284832	700	50	10	429	1	404	0.0e+00	505	COG3347	Rhamnose utilisation protein RhaD, predicted bifunctional aldolase and dehydrogenase	404
648284833	283	32.95	16	271	1	253	5.0e-57	214	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
648284834	334	31.19	1	310	4	314	3.0e-41	162	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
648284835	513	52.71	13	509	1	499	0.0e+00	630	COG1129	ABC-type sugar transport system, ATPase component	500
648284836	327	41.88	11	318	12	316	4.0e-55	208	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
648284837	330	36.48	26	330	12	316	5.0e-51	195	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
648284838	106	50.48	3	106	1	105	2.0e-30	123	COG3254	L-rhamnose mutarotase	105
648284839	464	24.11	5	422	4	447	7.0e-52	198	COG1070	Sugar (pentulose or hexulose) kinase	502
648284841	541	38.23	1	540	4	562	3.0e-116	412	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
648284842	307	41.32	1	307	1	315	4.0e-74	271	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648284843	311	38.7	20	311	2	287	4.0e-60	225	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648284844	602	52.72	1	530	4	531	0.0e+00	645	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
648284845	215	26.7	1	206	2	201	9.0e-06	43.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648284846	349	26.5	2	345	11	358	2.0e-40	160	COG0687	Spermidine/putrescine-binding periplasmic protein	363
648284847	285	41.04	9	274	6	272	2.0e-54	206	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
648284848	256	36.33	2	256	10	265	5.0e-45	174	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
648284849	341	47.06	1	328	2	340	4.0e-100	358	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
648284850	242	27.08	9	240	2	230	4.0e-17	81.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648284851	332	36.96	30	325	1	301	3.0e-61	229	COG0010	Arginase family enzyme	305
648284855	628	25.52	180	605	2	410	2.0e-38	154	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
648284858	654	29.46	296	643	105	447	2.0e-39	157	COG5002	Signal transduction histidine kinase	459
648284861	119	34.29	19	119	1	104	7.0e-07	46	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
648284863	216	34.34	7	171	1	166	1.0e-36	146	COG2518	Protein-L-isoaspartate O-methyltransferase	209
648284864	468	31.18	27	436	44	457	2.0e-37	150	COG1538	Outer membrane protein TolC	457
648284867	187	40.46	1	131	1	131	2.0e-38	151	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
648284869	265	33.96	12	262	16	282	1.0e-38	153	COG3001	Fructosamine-3-kinase	286
648284870	244	31.58	3	241	20	285	1.0e-44	172	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
648284871	582	36.82	10	581	2	567	1.0e-118	421	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
648284873	399	35.35	8	397	6	383	6.0e-73	268	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
648284875	372	34.79	6	367	1	355	5.0e-70	258	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
648284876	210	27.04	1	193	1	191	2.0e-14	72.6	COG2910	Putative NADH-flavin reductase	211
648284877	428	36.38	7	428	1	408	5.0e-90	325	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
648284878	227	41.7	5	226	1	222	8.0e-69	253	COG1136	ABC-type lipoprotein export system, ATPase component	226
648284879	144	36.55	1	144	3	147	2.0e-16	78.7	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
648284881	196	25.77	1	191	2	195	6.0e-12	64.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648284884	428	46.36	3	324	2	331	1.0e-90	326	COG0460	Homoserine dehydrogenase	333
648284885	390	39.66	1	390	1	392	7.0e-70	257	COG0183	Acetyl-CoA acetyltransferase	392
648284886	155	27.17	63	152	22	113	7.0e-07	46.9	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
648284887	160	23.33	19	137	12	129	2.0e-11	61.9	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
648284888	197	28.57	15	144	1	125	5.0e-16	77.6	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
648284889	456	54	10	456	10	456	0.0e+00	536	COG3572	Gamma-glutamylcysteine synthetase	456
648284891	208	36.57	1	206	32	246	7.0e-44	170	COG1385	16S rRNA U1498 N3-methylase RsmE	246
648284892	343	37.07	49	342	7	289	3.0e-45	175	COG0382	4-hydroxybenzoate polyprenyltransferase	289
648284893	637	32.84	471	603	56	189	7.0e-22	99.1	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
648284895	217	28.27	1	184	2	182	9.0e-15	73.7	COG0406	Broad specificity phosphatase PhoE	208
648284896	351	24.07	9	329	8	324	4.0e-14	72.6	COG0686	Alanine dehydrogenase	371
648284897	376	21.17	8	346	8	353	4.0e-25	109	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
648284898	266	42.38	58	266	10	208	8.0e-42	163	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
648284899	194	51.6	1	186	4	191	2.0e-61	228	COG3175	Cytochrome c oxidase assembly protein Cox11	195
648284901	316	44.59	1	304	1	296	3.0e-80	292	COG0109	Polyprenyltransferase (heme O synthase)	304
648284902	287	31.45	29	273	16	225	6.0e-49	187	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
648284903	473	40.09	14	470	1	453	1.0e-110	393	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
648284904	375	33.78	1	370	13	345	4.0e-71	262	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
648284905	906	44.72	1	607	1	570	0.0e+00	587	COG0550	DNA topoisomerase IA	570
648284907	234	54.59	1	218	1	217	2.0e-80	292	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
648284908	201	62.19	1	199	11	211	3.0e-72	264	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
648284911	597	44.96	138	593	2	445	3.0e-129	455	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
648284912	419	40.99	6	405	2	404	7.0e-104	371	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
648284914	166	37.38	33	138	18	124	1.0e-12	66.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
648284915	158	28.95	41	153	12	125	1.0e-11	62.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
648284916	367	23.44	1	305	2	312	6.0e-23	101	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648284917	179	24.14	1	174	5	173	7.0e-11	60.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648284918	426	32.97	54	419	2	364	1.0e-56	214	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648284919	255	36.78	1	247	1	247	1.0e-26	113	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648284920	255	34.41	12	254	13	257	3.0e-38	152	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648284921	624	25.93	50	550	5	488	5.0e-63	236	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648284922	290	34.47	10	290	9	291	8.0e-57	214	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
648284923	523	34.71	24	427	5	387	4.0e-62	232	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648284924	124	49.11	10	120	15	125	3.0e-26	110	COG5349	Uncharacterized conserved protein, DUF983 family	126
648284925	455	32.25	11	447	1	459	7.0e-75	274	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
648284928	303	16.84	5	294	7	293	1.0e-06	47.8	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
648284933	305	54.39	1	292	1	294	9.0e-110	390	COG0777	Acetyl-CoA carboxylase beta subunit	294
648284934	425	45.06	1	425	1	422	3.0e-107	382	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
648284935	358	43.14	2	356	9	363	9.0e-106	377	COG1485	Predicted ATPase	367
648284936	412	25.21	35	397	38	381	4.0e-15	76.4	COG2814	Predicted arabinose efflux permease, MFS family	394
648284937	124	41.84	15	109	8	105	4.0e-16	76.9	COG0607	Rhodanese-related sulfurtransferase	110
648284938	466	45.15	10	456	2	449	0.0e+00	515	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
648284939	219	40.27	1	219	5	224	7.0e-33	134	COG1802	DNA-binding transcriptional regulator, GntR family	230
648284940	368	41.26	4	368	7	363	3.0e-88	318	COG0687	Spermidine/putrescine-binding periplasmic protein	363
648284941	479	51.85	13	305	1	297	2.0e-104	373	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
648284942	296	47.62	3	296	9	286	7.0e-70	257	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
648284943	272	51.53	2	262	7	267	2.0e-64	239	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
648284944	439	28.82	32	421	1	385	8.0e-45	175	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648284945	244	35.91	1	242	2	250	9.0e-37	147	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648284946	555	41.56	13	539	8	536	5.0e-126	445	COG0405	Gamma-glutamyltranspeptidase	539
648284947	333	37.54	1	332	2	332	6.0e-77	281	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648284948	169	31.33	3	168	8	173	2.0e-14	72.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648284949	425	49.08	47	425	1	379	6.0e-85	308	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648284950	463	39.19	1	462	5	497	0.0e+00	468	COG0554	Glycerol kinase	499
648284951	405	26.33	6	314	5	302	2.0e-20	94.2	COG0492	Thioredoxin reductase	305
648284952	457	30.44	1	403	4	429	1.0e-73	270	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
648284953	257	37.98	1	257	1	252	5.0e-53	201	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
648284954	264	48.09	17	251	64	294	1.0e-59	223	COG4302	Ethanolamine ammonia-lyase, small subunit	294
648284955	463	55.11	2	451	3	451	0.0e+00	665	COG4303	Ethanolamine ammonia-lyase, large subunit	453
648284956	480	26.56	183	478	42	326	9.0e-24	105	COG0642	Signal transduction histidine kinase	336
648284957	262	34.6	22	256	2	228	9.0e-45	173	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648284958	414	23.58	4	414	11	430	3.0e-26	113	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648284959	290	36.92	9	286	11	289	2.0e-50	192	COG1175	ABC-type sugar transport system, permease component	295
648284960	304	35.44	20	303	3	281	8.0e-56	210	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648284961	365	52.68	5	359	4	338	1.0e-120	426	COG3839	ABC-type sugar transport system, ATPase component	338
648284962	407	21.78	1	405	1	409	4.0e-28	119	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648284964	316	23.92	46	291	6	250	3.0e-20	92.8	COG0510	Thiamine kinase and related kinases	269
648284965	279	36.14	28	274	3	250	2.0e-54	205	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
648284966	288	36.36	176	284	20	125	4.0e-13	68.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
648284967	255	38.91	6	255	9	264	7.0e-49	187	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
648284968	139	31.45	12	135	1	121	3.0e-10	58	COG1846	DNA-binding transcriptional regulator, MarR family	126
648284969	342	25.81	19	292	33	310	1.0e-30	127	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648284970	482	34.45	12	475	1	474	2.0e-94	339	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
648284971	265	23.11	19	265	17	261	6.0e-13	68	COG0829	Urease accessory protein UreH	269
648284972	201	47.72	5	200	15	202	7.0e-49	186	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
648284973	567	54.64	1	566	2	567	0.0e+00	690	COG0804	Urease alpha subunit	568
648284974	224	66.34	107	207	2	102	4.0e-36	144	COG0832	Urease beta subunit	106
648284975	220	32.61	1	220	2	229	6.0e-22	97.6	COG0830	Urease accessory protein UreF	229
648284976	157	25.95	12	142	8	126	3.0e-11	61.4	COG2371	Urease accessory protein UreE	155
648284977	504	37.05	82	501	68	469	1.0e-90	327	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
648284978	237	45.73	4	234	3	236	6.0e-67	247	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
648284979	244	39.27	2	238	1	247	8.0e-60	223	COG4674	ABC-type uncharacterized transport system, ATPase component	249
648284980	346	30.53	12	326	7	314	1.0e-36	147	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
648284981	288	33.9	1	287	3	297	4.0e-33	135	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
648284982	411	29.58	27	375	4	355	8.0e-49	188	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648284984	582	33.57	4	269	2	274	2.0e-46	180	COG0388	Predicted amidohydrolase	274
648284985	475	39.41	8	473	3	475	1.0e-107	383	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
648284986	871	55.63	5	851	1	779	0.0e+00	953	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
648284989	235	42.24	5	234	9	236	2.0e-44	172	COG0284	Orotidine-5'-phosphate decarboxylase	240
648284991	299	33.22	16	295	4	290	4.0e-33	135	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
648284993	122	32.2	5	114	21	133	3.0e-08	50.8	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
648284994	391	47.29	10	353	2	352	6.0e-85	308	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
648284996	377	29.02	38	375	79	425	1.0e-50	194	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
648284997	621	44.19	3	621	2	638	0.0e+00	618	COG0323	DNA mismatch repair ATPase MutL	638
648284999	303	36.23	45	299	53	317	1.0e-47	183	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
648285000	206	23.47	1	181	2	195	7.0e-16	77.3	COG1011	FMN phosphatase YigB, HAD superfamily	229
648285001	150	46.67	1	150	1	148	1.0e-44	172	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
648285002	308	34.3	1	306	2	307	2.0e-27	116	COG0679	Predicted permease	311
648285003	59	36.17	5	51	14	59	4.0e-08	50	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
648285004	308	41.86	5	303	4	292	4.0e-75	274	COG1131	ABC-type multidrug transport system, ATPase component	293
648285006	122	35.04	7	121	1	113	1.0e-21	95.5	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
648285009	170	61.76	1	169	31	200	8.0e-67	246	COG3816	Uncharacterized protein	205
648285010	333	42.55	3	322	2	321	3.0e-60	225	COG0714	MoxR-like ATPase	329
648285016	460	39.08	2	454	6	480	4.0e-109	388	COG0260	Leucyl aminopeptidase	485
648285018	215	30.05	7	213	3	203	1.0e-39	156	COG0288	Carbonic anhydrase	207
648285021	340	54.01	2	332	1	333	7.0e-117	413	COG0136	Aspartate-semialdehyde dehydrogenase	334
648285022	628	39.64	20	618	1	580	0.0e+00	503	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
648285023	280	35.71	58	275	1	202	9.0e-40	157	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
648285024	305	39.41	7	302	12	318	1.0e-59	223	COG1171	Threonine dehydratase	347
648285025	249	45.08	8	249	4	243	2.0e-27	116	COG0368	Cobalamin synthase	246
648285026	339	43.87	20	337	9	334	3.0e-65	242	COG2038	NaMN:DMB phosphoribosyltransferase	347
648285027	168	48.85	3	168	1	174	8.0e-50	189	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
648285028	196	32.99	6	184	2	192	6.0e-16	77.6	COG0406	Broad specificity phosphatase PhoE	208
648285029	311	46.86	1	311	3	315	9.0e-71	260	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
648285032	95	32.86	1	70	1	70	1.0e-07	48.4	COG5454	Predicted secreted protein	89
648285033	234	21.72	1	232	3	245	2.0e-14	72.6	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
648285034	192	28.71	10	192	7	207	4.0e-12	65	COG0778	Nitroreductase	207
648285035	85	45.33	13	84	12	86	6.0e-15	72.7	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
648285042	327	27.56	3	284	1	268	2.0e-23	103	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
648285044	755	35.68	518	754	9	249	7.0e-43	169	COG1484	DNA replication protein DnaC	254
648285048	548	32.24	8	462	1	396	7.0e-74	271	COG0644	Dehydrogenase (flavoprotein)	396
648285049	156	52.32	6	156	1	151	1.0e-39	155	COG0782	Transcription elongation factor, GreA/GreB family	151
648285053	242	34.16	10	241	8	250	1.0e-45	176	COG0631	Serine/threonine protein phosphatase PrpC	262
648285054	232	32.06	1	200	1	206	2.0e-20	93.3	COG3913	Uncharacterized protein	227
648285055	1193	39.32	15	1193	15	1187	0.0e+00	882	COG3523	Type VI protein secretion system component VasK	1188
648285056	465	36.59	24	299	4	262	2.0e-55	210	COG3455	Type VI protein secretion system component VasF	262
648285058	444	50.67	1	444	1	445	0.0e+00	463	COG3522	Predicted component of the type VI protein secretion system	446
648285059	145	30.87	3	145	6	153	6.0e-19	86.9	COG3521	Predicted component of the type VI protein secretion system	159
648285060	453	27.85	1	453	1	427	2.0e-52	200	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
648285061	96	35.11	5	95	4	97	9.0e-07	45.3	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
648285063	708	39.71	9	562	10	548	0.0e+00	494	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
648285066	889	39.59	12	888	1	783	0.0e+00	764	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
648285067	339	42.04	6	334	3	333	4.0e-66	245	COG3520	Predicted component of the type VI protein secretion system	335
648285068	624	42.81	1	624	1	621	0.0e+00	578	COG3519	Type VI protein secretion system component VasA	621
648285069	165	40.25	6	163	3	155	1.0e-20	92.7	COG3518	Predicted component of the type VI protein secretion system	157
648285070	278	44.62	1	259	6	264	1.0e-60	226	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion	273
648285071	177	22.58	1	153	1	151	1.0e-12	66.1	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
648285072	503	61.35	1	502	1	495	0.0e+00	759	COG3517	Predicted component of the type VI protein secretion system	495
648285073	169	56.21	2	169	1	169	3.0e-55	207	COG3516	Predicted component of the type VI protein secretion system	169
648285074	351	27.57	1	337	1	334	5.0e-20	92.1	COG3515	Predicted component of the type VI protein secretion system	346
648285075	445	33.68	18	284	1	285	4.0e-44	172	COG0515	Serine/threonine protein kinase	384
648285076	290	38.75	214	289	5	83	4.0e-07	48.9	COG2770	HAMP domain	83
648285080	178	34.46	1	171	5	181	1.0e-26	112	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
648285082	120	51.24	4	120	17	137	8.0e-31	125	COG4315	Predicted lipoprotein with conserved Yx(FWY)xxD motif (function unknown)	138
648285083	327	22.88	23	300	46	361	5.0e-18	85.4	COG1680	CubicO group peptidase, beta-lactamase class C family	390
648285084	477	33.11	51	476	16	443	9.0e-74	271	COG0174	Glutamine synthetase	443
648285086	329	29.06	1	305	49	347	9.0e-52	197	COG1740	Ni,Fe-hydrogenase I small subunit	355
648285087	476	30.05	4	476	2	530	1.0e-84	307	COG0374	Ni,Fe-hydrogenase I large subunit	545
648285088	742	45.43	5	740	1	750	0.0e+00	726	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
648285089	368	58.19	11	363	2	355	0.0e+00	517	COG1740	Ni,Fe-hydrogenase I small subunit	355
648285090	597	55.21	15	597	1	545	0.0e+00	688	COG0374	Ni,Fe-hydrogenase I large subunit	545
648285092	258	48.64	38	253	10	227	1.0e-54	206	COG1969	Ni,Fe-hydrogenase I cytochrome b subunit	227
648285093	202	34.84	3	157	2	156	2.0e-29	122	COG0680	Ni,Fe-hydrogenase maturation factor	160
648285094	106	32.05	1	74	1	77	3.0e-09	53.7	COG0298	Hydrogenase maturation factor	82
648285097	276	42	20	69	4	53	5.0e-12	65.3	COG1773	Rubredoxin	55
648285099	113	43.75	1	112	1	112	7.0e-23	99.2	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
648285101	225	42.79	15	216	1	201	5.0e-58	217	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
648285102	496	34.65	8	488	6	458	2.0e-93	336	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
648285103	102	57.5	1	80	1	76	6.0e-17	79.2	COG0298	Hydrogenase maturation factor	82
648285104	380	50.8	1	374	1	364	0.0e+00	470	COG0409	Hydrogenase maturation factor	364
648285105	347	46.11	13	347	1	339	6.0e-88	317	COG0309	Hydrogenase maturation factor	339
648285106	251	44.98	1	249	1	249	7.0e-79	287	COG4604	ABC-type enterochelin transport system, ATPase component	252
648285107	314	42.36	1	314	3	316	7.0e-69	254	COG4605	ABC-type enterochelin transport system, permease component	316
648285108	311	44.88	8	302	11	313	9.0e-72	263	COG4606	ABC-type enterochelin transport system, permease component	321
648285109	302	44.83	13	297	33	320	3.0e-73	268	COG4607	ABC-type enterochelin transport system, periplasmic component	320
648285110	94	42.86	4	86	3	86	1.0e-14	71.6	COG3553	Uncharacterized protein	96
648285111	641	19.75	3	641	7	699	4.0e-19	90.4	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
648285112	480	49.49	1	480	1	485	0.0e+00	565	COG1492	Cobyric acid synthase	486
648285113	140	41.43	1	140	1	140	2.0e-30	124	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
648285114	355	34.01	9	345	41	362	4.0e-91	328	COG1932	Phosphoserine aminotransferase	365
648285116	531	47.55	1	324	2	323	3.0e-94	339	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
648285118	590	31.23	9	575	1	548	2.0e-94	339	COG0659	Sulfate permease or related transporter, MFS superfamily	554
648285119	557	51.54	1	129	1	130	1.0e-36	148	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
648285120	73	40	1	73	1	72	8.0e-15	71.8	COG0254	Ribosomal protein L31	75
648285121	127	65.52	1	116	3	114	5.0e-39	153	COG0335	Ribosomal protein L19	115
648285122	271	53.74	35	260	3	227	1.0e-93	335	COG0336	tRNA G37 N-methylase TrmD	240
648285125	173	39.39	12	173	10	174	7.0e-41	159	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
648285126	280	28.57	54	272	35	254	2.0e-23	103	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
648285127	124	62.92	2	90	1	87	1.0e-25	108	COG0228	Ribosomal protein S16	87
648285128	101	33.7	9	99	4	95	9.0e-14	68.4	COG1605	Chorismate mutase	101
648285129	201	24.68	6	154	2	159	5.0e-11	61.1	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648285130	172	29.56	4	152	1	158	8.0e-15	73.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648285131	176	25.29	7	168	3	172	8.0e-16	76.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648285132	177	31.17	4	146	3	156	1.0e-14	72.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648285133	502	52.55	1	451	1	448	0.0e+00	531	COG0541	Signal recognition particle GTPase	451
648285135	293	27.33	3	293	2	297	4.0e-27	115	COG0583	DNA-binding transcriptional regulator, LysR family	297
648285137	117	32.5	1	79	11	90	2.0e-08	51	COG0640	DNA-binding transcriptional regulator, ArsR family	110
648285138	115	32.73	3	110	6	115	2.0e-11	60.8	COG5336	FoF1-type ATP synthase assembly protein I	116
648285139	254	33.94	37	253	28	246	5.0e-34	138	COG0356	FoF1-type ATP synthase, membrane subunit a	246
648285141	183	29.05	36	182	9	156	2.0e-11	62.6	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
648285142	187	34.64	33	185	10	161	2.0e-13	69.5	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
648285143	269	21.12	1	233	1	232	3.0e-19	89.5	COG1192	Cellulose biosynthesis protein BcsQ	259
648285144	185	36.42	13	185	12	182	1.0e-14	73.3	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
648285148	1151	31.88	1	1150	1	1163	0.0e+00	533	COG1196	Chromosome segregation ATPase	1163
648285149	429	30.37	3	423	7	419	2.0e-57	216	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
648285150	315	40.32	5	314	2	304	3.0e-67	249	COG1079	ABC-type uncharacterized transport system, permease component	304
648285151	348	41.83	1	347	1	349	3.0e-68	252	COG4603	ABC-type uncharacterized transport system, permease component	356
648285152	513	50.3	9	506	1	501	0.0e+00	593	COG3845	ABC-type uncharacterized transport system, ATPase component	501
648285153	343	27.75	6	340	1	341	9.0e-52	197	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
648285154	331	33.59	60	320	2	227	1.0e-53	203	COG0274	Deoxyribose-phosphate aldolase	228
648285155	114	26.67	1	102	1	105	7.0e-15	72.7	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
648285156	394	47.09	1	392	1	395	0.0e+00	470	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
648285157	285	44.93	9	284	12	284	2.0e-81	295	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
648285158	156	51.68	8	155	3	150	1.0e-46	178	COG0691	tmRNA-binding protein	153
648285159	448	28.83	125	448	8	329	8.0e-35	141	COG0642	Signal transduction histidine kinase	336
648285160	222	43.04	1	220	1	229	5.0e-54	204	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648285161	119	60.17	2	119	7	124	1.0e-42	164	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
648285162	471	52	297	471	1	172	2.0e-55	210	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
648285163	165	45.12	1	161	1	164	7.0e-43	166	COG3194	Ureidoglycolate hydrolase (allantoin degradation)	168
648285167	221	34.65	3	201	2	200	4.0e-32	131	COG0625	Glutathione S-transferase	211
648285169	344	45.35	1	342	2	337	5.0e-94	338	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
648285171	140	65.08	3	128	11	136	2.0e-56	210	COG0229	Peptide methionine sulfoxide reductase MsrB	140
648285172	168	47.65	1	164	5	174	5.0e-61	227	COG0225	Peptide methionine sulfoxide reductase MsrA	174
648285173	234	24.88	14	217	2	214	3.0e-22	99.1	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
648285174	180	27.92	24	176	18	157	2.0e-10	58.9	COG4461	Uncharacterized protein YPO0702	185
648285175	169	36.54	11	114	8	108	3.0e-13	68	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
648285176	203	24.4	7	179	18	218	4.0e-12	64.9	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
648285177	153	29.75	7	127	5	124	3.0e-18	84.7	COG3791	Uncharacterized conserved protein	133
648285178	669	45.3	3	355	2	362	9.0e-105	374	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
648285179	186	39.46	8	181	4	187	3.0e-29	121	COG0693	Putative intracellular protease/amidase	188
648285180	301	33.77	3	299	2	297	2.0e-44	172	COG0583	DNA-binding transcriptional regulator, LysR family	297
648285183	102	53.85	7	97	5	94	6.0e-31	125	COG4311	Sarcosine oxidase delta subunit	97
648285184	996	36.8	604	995	1	378	1.0e-104	374	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
648285185	184	34.29	10	181	17	189	5.0e-30	124	COG4583	Sarcosine oxidase gamma subunit	189
648285186	469	47.7	184	465	1	262	3.0e-78	286	COG1760	L-serine deaminase	262
648285187	294	62.54	1	282	5	287	7.0e-129	453	COG0788	Formyltetrahydrofolate hydrolase	287
648285188	127	26.56	5	126	2	129	1.0e-07	49.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
648285189	1154	34.44	220	485	1	268	2.0e-61	231	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
648285192	230	38.43	1	214	5	219	3.0e-31	128	COG1802	DNA-binding transcriptional regulator, GntR family	230
648285193	325	44.92	1	325	2	352	8.0e-99	353	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
648285194	424	19.83	8	358	4	320	4.0e-21	96.3	COG0687	Spermidine/putrescine-binding periplasmic protein	363
648285195	304	36.1	29	302	9	282	1.0e-50	193	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
648285196	279	34.81	1	268	3	267	1.0e-40	160	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
648285197	213	43	1	205	1	207	4.0e-40	158	COG4126	Asp/Glu/hydantoin racemase	230
648285200	588	26.08	5	581	118	753	9.0e-96	344	COG4993	Glucose dehydrogenase	773
648285203	320	23.77	2	307	21	340	1.0e-26	114	COG3391	DNA-binding beta-propeller fold protein YncE	381
648285205	224	24.39	41	163	30	149	3.0e-07	49.2	COG2010	Cytochrome c, mono- and diheme variants	150
648285206	290	17.12	1	288	5	269	9.0e-09	54.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
648285207	506	46.52	19	501	1	472	0.0e+00	502	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648285208	696	25.34	40	451	55	480	6.0e-31	129	COG3901	Regulator of nitric oxide reductase transcription	482
648285209	294	30.2	3	266	8	301	2.0e-32	132	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
648285211	1142	54.72	287	1142	1	808	0.0e+00	1073	COG4196	Uncharacterized conserved protein, DUF2126 family	808
648285212	798	37.04	20	503	12	488	0.0e+00	487	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
648285213	294	27.97	3	281	9	292	5.0e-35	141	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
648285216	276	30.33	1	275	2	300	4.0e-24	105	COG3734	2-keto-3-deoxy-galactonokinase	306
648285217	162	44.53	20	145	3	130	4.0e-30	124	COG1720	tRNA (Thr-GGU) A37 N-methylase	156
648285218	254	32.82	1	252	12	269	4.0e-42	165	COG0829	Urease accessory protein UreH	269
648285219	100	70	1	100	1	100	1.0e-41	161	COG0831	Urease gamma subunit	100
648285221	101	62.38	1	101	1	101	5.0e-43	165	COG0832	Urease beta subunit	106
648285224	582	73.49	2	582	1	568	0.0e+00	1014	COG0804	Urease alpha subunit	568
648285227	180	40.3	21	150	22	155	1.0e-22	99.6	COG2371	Urease accessory protein UreE	155
648285228	224	42.79	13	224	1	229	1.0e-44	173	COG0830	Urease accessory protein UreF	229
648285229	211	50.49	1	204	5	202	5.0e-61	227	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
648285230	304	32.82	38	293	17	273	7.0e-50	191	COG1351	Thymidylate synthase ThyX	273
648285231	144	29.2	4	124	2	138	1.0e-11	62.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
648285233	165	27.52	28	135	1	107	3.0e-06	44.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
648285234	86	38.75	1	79	7	85	2.0e-14	71	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
648285236	400	46.55	6	400	1	393	2.0e-111	396	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
648285240	263	45.6	7	254	5	253	5.0e-66	244	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
648285242	247	36.4	1	222	2	221	1.0e-25	110	COG0705	Membrane associated serine protease, rhomboid family	228
648285243	1142	49.08	440	1138	7	766	0.0e+00	741	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
648285244	162	45.58	6	152	4	149	8.0e-29	119	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648285249	690	20.33	13	193	1	174	9.0e-15	76	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
648285251	259	26.72	5	249	1	225	1.0e-24	107	COG3547	Transposase	303
648285252	268	34.39	10	260	5	236	2.0e-25	109	COG3547	Transposase	303
648285259	504	50.5	3	504	2	500	0.0e+00	589	COG0427	Acyl-CoA hydrolase	501
648285262	195	64.62	1	195	3	195	6.0e-82	296	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
648285263	275	46.47	28	268	4	242	6.0e-61	227	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
648285265	996	41.33	6	996	1	930	0.0e+00	1016	COG0060	Isoleucyl-tRNA synthetase	933
648285268	233	26.03	18	233	10	228	1.0e-13	70.4	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
648285269	344	37.5	17	344	25	345	3.0e-54	205	COG3768	Uncharacterized membrane protein YcjF, UPF0283 family	350
648285271	475	40.88	14	475	5	466	1.0e-115	410	COG3106	Predicted ATPase, YcjX-like family	467
648285272	493	30.54	64	492	5	326	3.0e-42	166	COG0306	Phosphate/sulfate permease	326
648285274	255	42.46	1	252	1	247	7.0e-77	280	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
648285275	398	53.73	7	392	17	401	0.0e+00	488	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
648285276	308	50.16	1	307	6	310	4.0e-115	408	COG0078	Ornithine carbamoyltransferase	310
648285277	814	36.94	1	813	46	845	0.0e+00	599	COG1643	HrpA-like RNA helicase	845
648285279	329	49.69	1	321	2	320	8.0e-89	320	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
648285280	96	60.27	1	73	1	73	9.0e-21	91.9	COG0227	Ribosomal protein L28	77
648285282	154	48	1	146	1	148	4.0e-28	117	COG2847	Copper(I)-binding protein	151
648285283	229	43.88	2	229	12	247	2.0e-61	228	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
648285284	151	39.74	1	149	1	138	8.0e-32	129	COG0394	Protein-tyrosine-phosphatase	139
648285287	547	58.64	3	545	2	531	0.0e+00	840	COG0504	CTP synthase (UTP-ammonia lyase)	533
648285288	127	38.36	1	70	1	73	7.0e-10	56.4	COG1314	Preprotein translocase subunit SecG	86
648285289	301	20.23	20	271	30	277	1.0e-05	44.4	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
648285290	231	30.54	12	205	5	206	6.0e-23	101	COG1564	Thiamine pyrophosphokinase	212
648285294	232	27.72	8	205	31	228	7.0e-27	114	COG5590	Ubiquinone biosynthesis protein COQ9	229
648285295	323	44.85	1	322	1	326	1.0e-74	273	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
648285296	284	42.86	38	284	30	281	7.0e-44	170	COG5473	Uncharacterized membrane protein	290
648285297	328	44.04	5	326	1	325	5.0e-74	271	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
648285298	367	33.33	3	343	1	354	4.0e-63	235	COG0116	23S rRNA G2445 N2-methylase RlmL	381
648285300	517	28.7	29	458	1	442	7.0e-70	258	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
648285301	432	20.37	3	322	2	318	4.0e-14	72.8	COG1344	Flagellin and related hook-associated protein FlgL	360
648285302	739	50.79	40	726	8	694	0.0e+00	859	COG0855	Polyphosphate kinase	696
648285304	356	30.75	11	345	18	349	2.0e-40	159	COG0628	Predicted PurR-regulated permease PerM	355
648285307	276	34.25	24	242	11	221	5.0e-43	167	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
648285308	841	36.71	6	839	7	828	0.0e+00	561	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
648285309	210	59.71	2	205	23	228	4.0e-70	257	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
648285310	228	32.69	38	222	11	213	7.0e-21	94.2	COG2755	Lysophospholipase L1 or related esterase	216
648285312	186	43.86	16	185	62	228	9.0e-34	136	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
648285314	221	20.6	18	216	4	184	2.0e-06	46.2	COG3334	Flagellar motility protein MotE, a chaperone for MotC folding	192
648285316	182	17.88	6	181	1	158	3.0e-07	48.3	COG1580	Flagellar basal body-associated protein FliL	159
648285317	546	31.65	2	538	8	545	4.0e-79	289	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
648285320	241	46.25	4	240	12	247	2.0e-59	222	COG1338	Flagellar biosynthetic protein FliP	248
648285321	309	53.29	2	304	5	308	2.0e-113	402	COG1054	Predicted sulfurtransferase	308
648285322	197	34.41	1	178	5	173	9.0e-30	123	COG1335	Nicotinamidase-related amidase	205
648285323	429	30.95	9	429	2	385	4.0e-75	275	COG1488	Nicotinic acid phosphoribosyltransferase	405
648285324	361	38.83	6	360	2	355	1.0e-83	303	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
648285325	302	38.46	1	284	1	279	2.0e-65	242	COG0287	Prephenate dehydrogenase	279
648285326	309	29.79	37	309	25	300	4.0e-35	142	COG3921	Uncharacterized conserved protein	300
648285328	186	38.66	45	163	10	127	6.0e-12	64.2	COG0526	Thiol-disulfide isomerase or thioredoxin	127
648285329	463	58.82	5	463	1	458	0.0e+00	626	COG0165	Argininosuccinate lyase	459
648285332	421	47.1	1	394	1	394	2.0e-113	402	COG0019	Diaminopimelate decarboxylase	394
648285335	166	21.95	1	164	27	174	5.0e-09	53.9	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
648285337	209	24.02	1	204	1	201	3.0e-10	58.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648285338	324	30.9	78	254	1	176	4.0e-31	128	COG1633	Rubrerythrin	176
648285339	935	51.55	328	935	3	593	0.0e+00	719	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
648285341	337	29.11	14	323	2	295	3.0e-38	152	COG0524	Sugar or nucleoside kinase, ribokinase family	311
648285342	214	55.39	10	213	6	209	8.0e-76	276	COG0177	Endonuclease III	211
648285344	278	33.33	115	274	1	168	2.0e-37	149	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
648285345	221	43.09	36	220	3	190	3.0e-37	148	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
648285346	132	27.34	8	128	3	136	1.0e-08	52.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
648285347	265	39.92	12	250	13	254	3.0e-50	191	COG3777	Hydroxyacyl-ACP dehydratase HTD2, hotdog domain	273
648285348	229	43.63	30	228	35	224	3.0e-49	188	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
648285350	202	20.62	8	201	28	215	1.0e-06	46.9	COG5375	Uncharacterized protein	216
648285351	165	29.63	5	156	9	160	1.0e-16	79.2	COG1934	Lipopolysaccharide export system protein LptA	173
648285352	252	66.11	15	251	5	243	3.0e-101	361	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
648285353	187	32.14	1	110	1	110	4.0e-18	84.5	COG1544	Ribosome-associated translation inhibitor RaiA	110
648285354	154	34.44	3	151	2	152	1.0e-23	102	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
648285358	400	19.53	116	400	78	374	3.0e-17	83.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648285359	327	50.76	3	327	2	328	1.0e-129	456	COG1087	UDP-glucose 4-epimerase	329
648285360	297	52.6	3	290	2	288	3.0e-109	388	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
648285362	256	48.45	2	248	13	263	2.0e-64	239	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
648285363	276	20	19	258	18	249	3.0e-11	62.5	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
648285365	158	34.51	1	138	7	145	1.0e-24	105	COG0071	Molecular chaperone IbpA, HSP20 family	146
648285366	250	19.17	14	200	51	228	7.0e-09	54.5	COG3591	V8-like Glu-specific endopeptidase	251
648285368	452	27.92	15	444	1	387	1.0e-67	250	COG0247	Fe-S oxidoreductase	388
648285370	370	27	2	369	37	455	3.0e-35	142	COG0277	FAD/FMN-containing dehydrogenase	459
648285371	480	39.83	20	469	1	459	9.0e-84	304	COG0277	FAD/FMN-containing dehydrogenase	459
648285372	124	36.15	1	124	20	149	3.0e-13	67.2	COG1981	Uncharacterized membrane protein	149
648285373	234	36.8	10	234	1	231	9.0e-40	157	COG3821	Uncharacterized membrane protein	234
648285378	433	22.51	166	384	45	260	7.0e-09	55.7	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
648285379	470	22.81	224	447	44	246	1.0e-12	68.1	COG0421	Spermidine synthase	282
648285381	253	36.67	21	77	11	70	6.0e-08	51.5	COG0695	Glutaredoxin	80
648285384	457	31.75	8	457	9	449	1.0e-64	241	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
648285385	144	30.56	1	143	2	144	2.0e-13	68.5	COG3909	Cytochrome c556	147
648285386	529	40.07	5	528	5	538	0.0e+00	478	COG0405	Gamma-glutamyltranspeptidase	539
648285387	346	43.23	39	334	11	315	4.0e-83	302	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
648285388	324	45.37	9	324	1	316	1.0e-100	360	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
648285389	299	44.88	17	297	6	288	6.0e-60	224	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648285390	316	43.4	1	316	1	317	1.0e-79	290	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648285391	535	30.46	13	523	2	541	3.0e-78	286	COG0747	ABC-type transport system, periplasmic component	556
648285392	213	36.28	1	213	13	227	3.0e-27	115	COG1802	DNA-binding transcriptional regulator, GntR family	230
648285393	274	31.6	6	268	2	251	5.0e-11	62	COG0730	Uncharacterized membrane protein YfcA	258
648285394	377	44.49	106	377	1	267	2.0e-58	219	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
648285395	263	52.38	3	253	2	253	5.0e-91	327	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
648285396	579	25.19	1	257	1	269	7.0e-22	99.4	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
648285397	201	27.46	10	200	14	204	2.0e-27	115	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
648285399	498	26.56	11	475	10	485	2.0e-87	316	COG0069	Glutamate synthase domain 2	485
648285401	301	41.58	21	274	8	271	2.0e-56	212	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
648285403	202	47.37	14	201	11	200	1.0e-36	146	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
648285419	177	43.65	1	177	2	182	2.0e-42	165	COG0088	Ribosomal protein L4	214
648285420	280	55.05	3	217	1	218	9.0e-77	280	COG0087	Ribosomal protein L3	218
648285421	102	72.55	1	102	1	102	7.0e-39	151	COG0051	Ribosomal protein S10	104
648285424	707	60.59	1	706	1	691	0.0e+00	953	COG0480	Translation elongation factor EF-G, a GTPase	697
648285425	156	60.14	2	149	1	148	5.0e-54	203	COG0049	Ribosomal protein S7	148
648285426	123	73.17	1	123	7	129	3.0e-47	180	COG0048	Ribosomal protein S12	129
648285428	315	22.86	25	299	10	289	1.0e-05	44.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
648285429	1418	51.11	21	850	6	808	0.0e+00	894	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
648285431	126	57.94	1	126	2	124	5.0e-22	96.8	COG0222	Ribosomal protein L7/L12	124
648285432	164	37.58	1	163	11	175	9.0e-31	126	COG0244	Ribosomal protein L10	175
648285434	233	61.4	1	227	1	228	1.0e-77	282	COG0081	Ribosomal protein L1	228
648285435	149	58.5	2	148	1	138	3.0e-45	174	COG0080	Ribosomal protein L11	141
648285436	177	49.15	1	176	1	177	3.0e-44	171	COG0250	Transcription antitermination factor NusG	178
648285437	63	31.48	3	56	19	72	1.0e-06	44.6	COG0690	Preprotein translocase subunit SecE	73
648285440	330	27.04	14	330	6	322	2.0e-46	179	COG0598	Mg2+ and Co2+ transporter CorA	322
648285442	391	80.56	1	391	1	394	0.0e+00	699	COG0050	Translation elongation factor EF-Tu, a GTPase	394
648285445	135	32.89	1	135	4	151	1.0e-09	55.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
648285446	231	32.17	1	221	1	229	9.0e-26	110	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648285448	237	21.93	9	235	6	216	9.0e-12	64.2	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
648285449	308	38.06	6	307	2	300	6.0e-64	237	COG4974	Site-specific recombinase XerD	300
648285450	201	25	1	199	1	203	1.0e-15	76.8	COG0625	Glutathione S-transferase	211
648285451	226	43.66	8	217	25	236	1.0e-56	213	COG0688	Phosphatidylserine decarboxylase	239
648285452	267	36.12	32	256	7	225	5.0e-41	161	COG1183	Phosphatidylserine synthase	234
648285453	98	36.63	7	98	12	112	2.0e-24	104	COG2824	Uncharacterized Zn-ribbon-containing protein	112
648285454	219	23.11	1	219	1	199	6.0e-06	44.6	COG3637	Opacity protein and related surface antigens	199
648285455	191	37.04	4	191	4	166	4.0e-34	137	COG0723	Rieske Fe-S protein	177
648285456	447	45.91	9	408	1	372	9.0e-88	317	COG1290	Cytochrome b subunit of the bc complex	381
648285457	264	33.2	12	260	4	250	4.0e-34	138	COG2857	Cytochrome c1	250
648285458	232	50	1	231	1	231	9.0e-64	236	COG3840	ABC-type thiamine transport system, ATPase component	231
648285459	513	33.71	4	508	5	533	2.0e-52	200	COG1178	ABC-type Fe3+ transport system, permease component	540
648285460	302	46.77	2	302	28	336	6.0e-79	287	COG4143	ABC-type thiamine transport system, periplasmic component	336
648285461	366	59.89	2	357	1	355	0.0e+00	518	COG0082	Chorismate synthase	369
648285462	622	35.91	264	575	74	406	2.0e-40	160	COG0840	Methyl-accepting chemotaxis protein	408
648285463	292	22.73	21	284	29	283	4.0e-06	45.6	COG5006	Threonine/homoserine efflux transporter RhtA	292
648285464	367	32.77	2	290	6	298	3.0e-57	215	COG0863	DNA modification methylase	302
648285465	215	55.08	25	207	2	188	1.0e-62	232	COG0164	Ribonuclease HII	199
648285466	252	40.87	3	243	2	251	3.0e-44	171	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648285468	547	49.54	1	532	1	521	0.0e+00	502	COG0459	Chaperonin GroEL (HSP60 family)	524
648285469	97	67.74	1	93	1	93	1.0e-31	127	COG0234	Co-chaperonin GroES (HSP10)	96
648285470	323	17.48	23	301	7	292	4.0e-08	52.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
648285471	219	44.19	4	215	3	214	8.0e-49	187	COG5482	Uncharacterized protein	229
648285472	329	27.99	36	326	17	297	1.0e-32	133	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
648285473	673	42.75	1	673	3	683	0.0e+00	725	COG0339	Zn-dependent oligopeptidase	683
648285474	348	51.78	100	348	1	253	5.0e-75	274	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
648285475	145	63.43	12	145	18	148	2.0e-46	177	COG0756	dUTPase	148
648285476	398	49.25	1	396	1	391	4.0e-106	378	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
648285477	279	22.61	32	244	56	267	1.0e-15	77.4	COG3016	Uncharacterized iron-regulated protein	295
648285478	292	38.03	7	286	68	337	2.0e-52	199	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
648285479	504	53.69	14	497	1	485	0.0e+00	560	COG0606	Predicted ATPase with chaperone activity	490
648285480	299	34.95	1	289	1	306	2.0e-34	140	COG0657	Acetyl esterase/lipase	312
648285481	311	41.05	1	311	1	316	8.0e-70	257	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
648285482	153	33.33	44	152	3	113	3.0e-15	74.5	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
648285483	278	48.13	2	269	10	274	4.0e-77	281	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
648285484	396	23.58	49	376	9	349	6.0e-13	69	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648285485	915	39.75	36	907	1	864	0.0e+00	760	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
648285486	143	31.93	27	143	6	112	2.0e-12	64.9	COG1416	Intracellular sulfur oxidation protein, DsrE/DsrF family	112
648285487	328	44.38	6	328	16	342	2.0e-75	276	COG3569	DNA topoisomerase IB	354
648285488	524	33.01	307	502	11	214	3.0e-34	140	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
648285489	157	35.48	16	139	3	122	4.0e-11	61.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
648285492	762	39.62	140	762	1	557	0.0e+00	569	COG1982	Arginine/lysine/ornithine decarboxylase	557
648285493	581	39.01	58	556	6	491	5.0e-92	332	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
648285494	321	50.47	9	314	2	317	1.0e-103	369	COG1494	Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase or related protein	332
648285495	215	42.4	7	215	73	289	3.0e-56	211	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
648285496	479	43.86	6	473	2	465	5.0e-129	454	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648285497	217	33.51	1	188	1	183	3.0e-47	181	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
648285499	431	65.48	10	429	2	413	0.0e+00	672	COG0112	Glycine/serine hydroxymethyltransferase	413
648285500	253	29.29	17	252	39	275	5.0e-48	184	COG0061	NAD kinase	281
648285501	67	45.31	1	64	3	66	1.0e-08	51.5	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
648285502	127	27.66	3	126	1	138	3.0e-10	57.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
648285503	633	38.21	44	602	1	524	0.0e+00	529	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
648285505	759	53.88	2	436	10	432	0.0e+00	548	COG0281	Malic enzyme	432
648285507	306	38.49	3	304	4	304	4.0e-60	225	COG1227	Inorganic pyrophosphatase/exopolyphosphatase	311
648285508	290	22.14	12	259	22	281	2.0e-24	106	COG2017	Galactose mutarotase or related enzyme	308
648285509	290	31.2	8	267	1	252	9.0e-43	167	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
648285510	151	39.19	10	149	11	158	4.0e-22	97.5	COG2030	Acyl dehydratase	159
648285511	287	23.42	3	285	1	310	3.0e-18	86.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
648285514	396	38.31	132	392	14	267	6.0e-54	205	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
648285515	562	44.1	334	562	60	286	2.0e-66	247	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
648285516	342	28.57	23	341	31	307	3.0e-34	139	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
648285517	85	62.35	1	85	1	85	4.0e-25	106	COG3811	Uncharacterized protein YjhX, UPF0386 family	85
648285519	257	38.78	1	255	1	251	6.0e-46	177	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648285520	606	25.87	11	569	9	530	4.0e-71	263	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
648285522	234	33.33	14	220	1	205	6.0e-40	157	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
648285523	373	33.16	6	364	10	379	2.0e-54	206	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
648285524	738	35.21	333	596	74	336	6.0e-36	146	COG0642	Signal transduction histidine kinase	336
648285525	527	26.35	19	500	2	519	2.0e-34	140	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
648285526	217	26.9	46	216	19	181	1.0e-18	87	COG5342	Invasion protein IalB, involved in pathogenesis	181
648285527	385	43.38	1	380	2	377	2.0e-101	362	COG0763	Lipid A disaccharide synthetase	381
648285528	261	37.73	2	260	7	279	9.0e-47	180	COG3494	Uncharacterized conserved protein, DUF1009 family	279
648285529	262	49.42	1	258	1	259	2.0e-87	315	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
648285530	153	51.7	5	150	1	144	5.0e-41	160	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
648285531	190	20.93	6	175	4	169	2.0e-07	49.2	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
648285532	756	31.94	2	756	11	766	0.0e+00	495	COG4775	Outer membrane protein assembly factor BamA	766
648285534	447	31.88	13	445	1	371	2.0e-46	180	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
648285535	390	47.93	1	385	1	380	3.0e-123	435	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
648285536	262	32.7	8	254	1	263	1.0e-31	130	COG0575	CDP-diglyceride synthetase	265
648285537	241	54.59	11	239	17	245	2.0e-84	305	COG0020	Undecaprenyl pyrophosphate synthase	245
648285538	187	48.11	4	187	3	187	1.0e-55	209	COG0233	Ribosome recycling factor	187
648285539	211	33.49	2	211	6	220	1.0e-37	150	COG0569	Trk K+ transport system, NAD-binding component	225
648285540	451	34.3	47	436	75	484	3.0e-65	242	COG0168	Trk-type K+ transport system, membrane component	499
648285541	241	60.68	9	241	5	238	1.0e-85	309	COG0528	Uridylate kinase	238
648285542	304	40.36	22	293	6	284	8.0e-65	240	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
648285543	256	23.33	126	245	1	120	2.0e-11	63.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
648285544	561	25.74	26	555	6	549	2.0e-53	203	COG0747	ABC-type transport system, periplasmic component	556
648285545	382	36.99	1	364	27	363	2.0e-71	263	COG1858	Cytochrome c peroxidase	364
648285547	171	41.42	3	171	1	167	6.0e-34	136	COG0629	Single-stranded DNA-binding protein	167
648285551	307	20.88	3	296	18	288	3.0e-21	96.2	COG0685	5,10-methylenetetrahydrofolate reductase	291
648285552	220	34.53	1	219	1	221	3.0e-37	148	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
648285554	337	34.63	4	295	7	311	2.0e-64	240	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
648285555	361	42.52	42	335	1	289	2.0e-72	266	COG1533	DNA repair photolyase	297
648285556	234	46.7	1	226	1	227	4.0e-64	237	COG5012	Methanogenic corrinoid protein MtbC1	227
648285559	586	24.6	350	583	3	248	1.0e-07	52.2	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
648285560	193	57.45	1	187	3	189	2.0e-73	268	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
648285561	340	51.92	2	338	1	338	6.0e-102	364	COG0547	Anthranilate phosphoribosyltransferase	338
648285562	218	47.56	1	214	1	223	2.0e-69	255	COG0692	Uracil DNA glycosylase	223
648285563	267	55.25	6	262	1	254	2.0e-81	295	COG0134	Indole-3-glycerol phosphate synthase	254
648285564	158	61.78	1	157	1	156	2.0e-56	211	COG0315	Molybdenum cofactor biosynthesis enzyme	157
648285565	386	45.01	3	386	11	401	5.0e-94	338	COG0303	Molybdopterin biosynthesis enzyme	404
648285566	231	40.26	1	231	3	200	2.0e-50	192	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
648285567	678	24.59	66	484	48	444	9.0e-27	115	COG0658	Predicted membrane metal-binding protein	453
648285568	468	40.8	2	462	9	469	4.0e-118	418	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
648285569	432	52.35	29	432	1	390	0.0e+00	484	COG0372	Citrate synthase	390
648285570	258	40.78	1	252	2	255	5.0e-47	181	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648285571	152	43.54	5	151	8	151	3.0e-34	137	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
648285572	655	51.39	1	645	1	648	0.0e+00	604	COG1138	Cytochrome c biogenesis factor	648
648285575	144	52.45	3	139	2	142	2.0e-37	148	COG3542	Predicted sugar epimerase, cupin superfamily	162
648285577	527	48.13	37	516	3	446	0.0e+00	490	COG0166	Glucose-6-phosphate isomerase	446
648285578	225	29.65	3	223	1	226	3.0e-34	138	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
648285579	486	51.63	5	483	2	482	0.0e+00	617	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
648285580	312	56.41	1	312	1	310	9.0e-115	406	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
648285582	310	39.13	18	291	6	275	2.0e-62	232	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
648285583	486	44.01	21	486	10	488	0.0e+00	525	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
648285584	306	29.21	16	306	1	288	2.0e-08	53.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
648285585	276	28.05	71	272	1	221	3.0e-13	69.6	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
648285587	238	40.66	1	237	1	234	1.0e-59	222	COG2872	Ser-tRNA(Ala) deacylase AlaX (editing enzyme)	241
648285590	342	48.71	3	310	1	300	1.0e-95	343	COG0031	Cysteine synthase	300
648285593	473	40.76	4	469	1	458	4.0e-107	381	COG0415	Deoxyribodipyrimidine photolyase	461
648285594	399	29.16	1	397	2	401	1.0e-64	240	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
648285595	548	47.67	39	548	7	502	0.0e+00	491	COG1292	Choline-glycine betaine transporter	537
648285597	330	32.04	2	328	1	326	4.0e-48	185	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
648285598	171	29.17	1	168	1	166	1.0e-22	99.3	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
648285599	249	36.28	1	224	1	223	1.0e-28	120	COG2186	DNA-binding transcriptional regulator, FadR family	241
648285601	353	34.52	7	337	17	349	3.0e-68	252	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
648285602	265	29.08	26	165	12	151	6.0e-20	91.5	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
648285603	475	40.65	14	474	11	447	4.0e-94	338	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
648285605	577	17.77	90	552	43	505	8.0e-27	115	COG0366	Glycosidase	505
648285608	1158	43.69	3	1149	9	1137	0.0e+00	1263	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
648285610	332	55.56	8	330	5	327	0.0e+00	466	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
648285613	269	20.76	35	269	16	231	2.0e-17	82.6	COG3547	Transposase	303
648285615	400	35.42	19	384	15	371	1.0e-76	280	COG3328	Transposase (or an inactivated derivative)	379
648285616	334	33.86	10	324	5	302	4.0e-32	132	COG3547	Transposase	303
648285617	299	35.65	64	293	22	232	6.0e-18	85	COG2801	Transposase InsO and inactivated derivatives	232
648285620	440	23.72	27	407	1	383	1.0e-38	154	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648285621	342	47.92	1	313	1	266	2.0e-93	336	COG4608	ABC-type oligopeptide transport system, ATPase component	309
648285622	346	53.09	12	334	1	316	4.0e-117	414	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
648285623	295	48.91	21	293	13	286	8.0e-71	260	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648285624	303	44.88	2	303	15	316	7.0e-81	293	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648285625	547	25	12	547	7	556	2.0e-79	290	COG0747	ABC-type transport system, periplasmic component	556
648285626	423	29.79	2	414	8	384	9.0e-51	194	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648285627	233	26.22	1	214	4	226	7.0e-23	100	COG0300	Short-chain dehydrogenase	265
648285628	168	30.93	54	150	26	122	2.0e-10	58.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
648285629	69	39.66	13	69	11	68	1.0e-09	54.5	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
648285634	569	16.93	1	563	2	543	9.0e-33	135	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
648285635	251	48.82	2	249	1	251	2.0e-46	179	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648285636	816	46.19	1	478	11	493	0.0e+00	490	COG1129	ABC-type sugar transport system, ATPase component	500
648285637	335	32.36	27	333	8	316	4.0e-37	148	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
648285639	256	20	4	253	3	258	1.0e-06	46.9	COG0730	Uncharacterized membrane protein YfcA	258
648285640	326	31.93	1	326	1	326	8.0e-45	174	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
648285641	203	24.24	1	195	4	201	2.0e-08	53.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648285642	165	18.75	8	151	3	137	5.0e-07	47.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
648285643	295	29.33	2	295	1	294	2.0e-23	103	COG0583	DNA-binding transcriptional regulator, LysR family	297
648285645	187	25.29	10	173	7	176	6.0e-12	64	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
648285647	678	35.95	1	365	1	363	5.0e-93	335	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
648285648	210	27.04	20	178	18	175	1.0e-05	43.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648285649	418	32.15	19	410	4	366	2.0e-68	253	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
648285650	362	29.17	16	302	2	266	5.0e-56	211	COG1018	Ferredoxin-NADP reductase	266
648285651	490	44.12	2	483	40	524	0.0e+00	514	COG5598	Trimethylamine:corrinoid methyltransferase	526
648285652	367	28.34	1	359	4	362	1.0e-43	170	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
648285653	440	24.21	27	422	1	387	4.0e-27	116	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648285654	497	48.64	21	490	1	471	0.0e+00	474	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648285655	300	31.62	1	288	3	291	2.0e-68	252	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
648285656	240	32.29	1	223	10	227	6.0e-29	121	COG1802	DNA-binding transcriptional regulator, GntR family	230
648285657	359	52.51	10	348	5	332	1.0e-112	399	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
648285658	328	50.36	18	296	11	288	2.0e-80	292	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
648285659	329	26.93	6	327	7	300	1.0e-43	170	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
648285660	317	44.34	2	309	8	315	1.0e-83	303	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
648285661	121	32.71	1	105	2	104	4.0e-13	66.9	COG5485	Predicted ester cyclase	131
648285662	256	21.51	1	231	7	235	2.0e-12	66.3	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
648285663	180	26.21	1	179	3	200	7.0e-22	96.8	COG1335	Nicotinamidase-related amidase	205
648285664	316	31.53	5	315	12	323	3.0e-62	232	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
648285666	504	28.34	8	495	2	469	1.0e-62	234	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648285667	241	35.11	4	228	1	210	7.0e-44	170	COG0684	Regulator of RNase E activity RraA	210
648285668	577	45.09	1	564	1	574	0.0e+00	659	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
648285670	438	36.24	8	436	9	444	7.0e-73	268	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
648285671	173	22.54	1	173	1	166	1.0e-07	49.6	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648285672	340	26.2	1	328	4	325	7.0e-36	145	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648285673	235	32.9	5	233	1	229	5.0e-28	117	COG1802	DNA-binding transcriptional regulator, GntR family	230
648285674	305	36.94	3	303	1	312	9.0e-67	247	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
648285675	243	33.48	13	241	9	241	2.0e-30	126	COG2186	DNA-binding transcriptional regulator, FadR family	241
648285676	423	36.56	26	396	1	348	4.0e-69	255	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
648285677	84	34.78	4	72	8	76	7.0e-07	45.5	COG5302	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid	80
648285679	256	38.67	5	254	3	250	2.0e-42	165	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648285680	125	55	3	122	7	126	1.0e-35	141	COG4334	Uncharacterized protein	131
648285682	399	36.65	17	389	13	393	2.0e-85	309	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
648285683	220	23.24	11	195	10	188	3.0e-08	52	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648285684	257	66.54	4	257	3	256	2.0e-114	405	COG4598	ABC-type histidine transport system, ATPase component	256
648285685	258	32.03	5	256	17	269	5.0e-39	154	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
648285686	239	49.34	15	238	4	230	6.0e-65	240	COG4215	ABC-type arginine transport system, permease component	230
648285687	276	48.25	48	274	1	224	4.0e-63	235	COG4160	ABC-type arginine/histidine transport system, permease component	228
648285688	318	30.5	18	318	9	324	3.0e-36	145	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
648285689	838	26.59	464	709	93	335	5.0e-23	103	COG0642	Signal transduction histidine kinase	336
648285690	244	42.11	14	239	3	225	6.0e-48	184	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648285691	326	27.61	48	310	24	290	3.0e-39	155	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
648285692	257	47.47	1	257	3	258	2.0e-81	295	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
648285693	268	34.13	20	267	31	281	6.0e-40	158	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
648285694	276	39.54	19	276	20	282	1.0e-48	187	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
648285695	298	31.97	33	297	1	257	3.0e-36	145	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
648285704	437	35.98	58	434	4	378	5.0e-63	235	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648285705	188	19.89	14	188	2	174	1.0e-07	49.6	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648285707	221	52.91	1	221	2	224	1.0e-79	289	COG0223	Methionyl-tRNA formyltransferase	307
648285708	321	52.65	1	321	2	304	2.0e-74	272	COG1079	ABC-type uncharacterized transport system, permease component	304
648285709	364	41.85	1	355	5	350	1.0e-70	260	COG4603	ABC-type uncharacterized transport system, permease component	356
648285710	532	54.38	4	503	3	501	0.0e+00	629	COG3845	ABC-type uncharacterized transport system, ATPase component	501
648285711	334	43.37	7	330	19	344	8.0e-72	264	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
648285712	139	34	6	136	27	176	8.0e-14	69.7	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
648285713	207	35.62	4	198	2	219	3.0e-26	111	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
648285714	186	51.22	105	184	3	84	6.0e-24	103	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
648285716	287	31.87	15	283	13	280	7.0e-45	174	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
648285717	626	46.7	17	622	3	581	0.0e+00	628	COG0322	Excinuclease UvrABC, nuclease subunit	581
648285718	263	34.6	1	250	1	250	2.0e-29	122	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648285719	320	40.13	1	317	10	318	6.0e-44	171	COG0530	Ca2+/Na+ antiporter	320
648285720	265	36.47	10	258	57	309	1.0e-50	193	COG0616	Periplasmic serine protease, ClpP class	317
648285721	729	46.56	18	728	11	730	0.0e+00	699	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
648285722	217	48.7	1	216	8	237	2.0e-64	238	COG0176	Transaldolase	239
648285725	224	28.29	16	221	4	254	2.0e-24	106	COG1192	Cellulose biosynthesis protein BcsQ	259
648285730	525	36.6	11	520	1	521	0.0e+00	524	COG1384	Lysyl-tRNA synthetase, class I	521
648285732	499	27.38	44	454	17	441	2.0e-40	160	COG2027	D-alanyl-D-alanine carboxypeptidase	470
648285733	204	33.85	14	204	1	175	1.0e-34	139	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
648285734	551	46.18	5	533	1	530	0.0e+00	571	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
648285736	68	60.29	1	68	1	67	2.0e-22	97.1	COG1278	Cold shock protein, CspA family	67
648285737	202	23.28	14	198	1	186	3.0e-06	45.4	COG0558	Phosphatidylglycerophosphate synthase	192
648285738	131	43.1	15	130	2	117	2.0e-24	105	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
648285739	256	43.55	9	255	15	258	2.0e-48	185	COG0725	ABC-type molybdate transport system, periplasmic component	258
648285740	230	55.56	4	227	1	224	2.0e-60	225	COG4149	ABC-type molybdate transport system, permease component	225
648285741	366	49.3	3	356	2	352	8.0e-108	383	COG4148	ABC-type molybdate transport system, ATPase component	352
648285742	273	27.98	17	251	1	237	1.0e-31	130	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
648285743	378	21.21	4	360	13	370	5.0e-23	102	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
648285744	190	28.33	15	190	26	205	2.0e-14	72.2	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
648285746	360	31.2	1	357	13	403	5.0e-53	201	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648285747	225	37.66	1	225	1	229	1.0e-42	166	COG3342	Uncharacterized conserved protein, Ntn-hydrolase superfamily	265
648285748	138	27.41	4	138	1	130	2.0e-17	81.9	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
648285749	374	25.36	24	358	5	341	2.0e-42	166	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
648285750	454	40.31	8	454	1	448	1.0e-123	436	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
648285751	255	36.07	1	234	3	244	3.0e-31	129	COG0388	Predicted amidohydrolase	274
648285752	341	37.61	3	341	12	361	9.0e-66	244	COG0687	Spermidine/putrescine-binding periplasmic protein	363
648285753	268	43.49	1	268	2	266	1.0e-54	206	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
648285754	306	41.32	16	302	6	280	3.0e-58	218	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
648285755	355	52.51	1	355	1	352	3.0e-112	398	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
648285758	332	39.76	4	326	9	335	6.0e-65	241	COG4448	L-asparaginase II	339
648285759	289	49.05	71	280	3	212	1.0e-55	209	COG0560	Phosphoserine phosphatase	212
648285760	634	23.81	446	634	57	243	3.0e-23	103	COG1360	Flagellar motor protein MotB	244
648285762	180	52.3	3	175	12	183	2.0e-45	175	COG3703	Cation transport regulator ChaC	190
648285763	309	21.41	7	308	29	338	3.0e-15	76.2	COG4093	Uncharacterized protein	338
648285764	454	31.54	32	451	2	407	2.0e-61	230	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648285765	190	58.33	1	190	1	184	5.0e-55	207	COG2096	Cob(I)alamin adenosyltransferase	184
648285767	277	27.21	1	276	4	259	8.0e-32	131	COG0300	Short-chain dehydrogenase	265
648285769	807	40.45	8	802	2	739	0.0e+00	718	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
648285772	252	50.96	1	252	1	259	1.0e-67	249	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
648285773	308	52.38	1	308	1	310	2.0e-82	299	COG2025	Electron transfer flavoprotein, alpha subunit	313
648285774	188	27.13	3	187	1	182	2.0e-22	98.6	COG0431	NAD(P)H-dependent FMN reductase	184
648285775	600	25.2	231	597	3	370	5.0e-27	116	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
648285776	219	29.52	15	216	37	241	5.0e-41	160	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
648285777	340	25	33	337	9	313	2.0e-26	113	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
648285779	198	28.5	3	195	8	201	1.0e-30	126	COG1573	Uracil-DNA glycosylase	202
648285781	333	40.36	1	321	9	331	5.0e-60	224	COG3191	L-aminopeptidase/D-esterase	348
648285782	246	43.7	1	244	1	250	4.0e-42	165	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648285783	490	44.14	19	485	1	465	2.0e-123	436	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648285784	570	53.53	29	553	2	536	0.0e+00	614	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
648285785	271	49.44	2	268	21	288	2.0e-62	232	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648285786	314	44.79	1	314	1	317	4.0e-82	298	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648285787	147	32.79	5	124	9	125	9.0e-12	63.1	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
648285788	379	35.33	8	349	5	355	5.0e-54	205	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
648285789	280	52.48	3	280	2	283	7.0e-96	343	COG0414	Panthothenate synthetase	285
648285790	277	58.62	15	273	8	268	7.0e-92	330	COG0413	Ketopantoate hydroxymethyltransferase	268
648285791	494	33.4	5	492	14	552	7.0e-81	294	COG0747	ABC-type transport system, periplasmic component	556
648285793	168	30.32	1	155	50	184	1.0e-16	79.6	COG3216	Uncharacterized conserved protein, DUF2062 family	184
648285794	712	40.77	1	698	6	700	0.0e+00	742	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
648285795	117	55.41	1	72	1	74	4.0e-12	63.4	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
648285796	188	35.56	9	187	6	160	6.0e-32	130	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
648285803	400	35.42	19	384	15	371	1.0e-76	280	COG3328	Transposase (or an inactivated derivative)	379
648285804	341	23	63	328	7	287	2.0e-09	57.1	COG4974	Site-specific recombinase XerD	300
648285807	406	51.74	1	399	2	400	0.0e+00	462	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
648285810	425	25.63	29	419	21	410	1.0e-54	207	COG0719	Fe-S cluster assembly scaffold protein SufB	412
648285811	251	63.35	1	251	3	248	2.0e-97	349	COG0396	Fe-S cluster assembly ATPase SufC	251
648285815	510	41.29	48	508	1	412	8.0e-123	434	COG0719	Fe-S cluster assembly scaffold protein SufB	412
648285816	344	42.26	2	341	1	377	1.0e-90	326	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
648285817	153	35.97	1	139	1	137	1.0e-28	119	COG1959	DNA-binding transcriptional regulator, IscR family	150
648285818	217	56.4	1	211	4	207	1.0e-73	269	COG2945	Alpha/beta superfamily hydrolase	210
648285820	197	30.99	14	145	5	140	2.0e-13	69.6	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
648285821	464	47.14	3	453	2	453	0.0e+00	485	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
648285822	207	47.19	18	195	9	182	2.0e-44	172	COG3803	Uncharacterized conserved protein, DUF924 family	182
648285824	349	52.69	1	349	1	344	6.0e-124	437	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
648285826	175	63.51	28	175	8	155	2.0e-53	201	COG1225	Peroxiredoxin	157
648285827	269	47.15	1	263	1	259	2.0e-67	249	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
648285828	415	34.25	160	405	10	258	4.0e-34	139	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
648285829	175	27.2	44	166	22	146	7.0e-18	83.8	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
648285830	801	66.45	7	777	8	782	0.0e+00	1158	COG0466	ATP-dependent Lon protease, bacterial type	782
648285833	364	41.6	1	363	2	362	2.0e-95	342	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
648285835	375	57.1	6	371	1	366	0.0e+00	518	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
648285839	502	38.09	1	480	28	509	2.0e-111	396	COG0513	Superfamily II DNA and RNA helicase	513
648285840	360	48.06	2	360	1	352	1.0e-115	410	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
648285841	261	36.9	6	256	10	261	5.0e-48	184	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
648285842	328	37.46	44	326	5	285	3.0e-56	212	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
648285843	368	26.12	1	368	1	362	2.0e-43	169	COG0687	Spermidine/putrescine-binding periplasmic protein	363
648285845	195	29.79	6	191	1	177	5.0e-19	87.5	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
648285846	160	31.33	16	158	30	179	4.0e-13	67.4	COG4950	N-terminal domain of uncharacterized protein YciW (function unknown)	193
648285847	487	23.48	35	487	2	439	1.0e-55	211	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
648285848	445	17.49	47	389	49	382	6.0e-06	45.6	COG2814	Predicted arabinose efflux permease, MFS family	394
648285849	486	29.38	36	424	19	404	1.0e-61	230	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
648285850	153	35.06	1	153	2	154	2.0e-26	111	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648285853	270	51.63	1	241	1	246	2.0e-77	282	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
648285854	183	24.86	8	183	9	187	4.0e-08	51.5	COG3009	Uncharacterized lipoprotein YmbA	190
648285855	794	31.49	2	496	9	493	1.0e-81	297	COG3008	Paraquat-inducible protein B	553
648285858	255	34.78	4	254	2	253	8.0e-50	190	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
648285859	160	24	9	155	1	150	8.0e-10	56.5	COG2847	Copper(I)-binding protein	151
648285861	227	35.62	7	223	7	224	6.0e-47	180	COG1136	ABC-type lipoprotein export system, ATPase component	226
648285863	499	31.76	1	497	20	478	8.0e-72	264	COG1785	Alkaline phosphatase	482
648285864	277	44.69	1	272	2	274	5.0e-47	181	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
648285865	291	43.22	1	272	2	274	3.0e-50	192	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
648285866	296	50.2	18	268	5	254	7.0e-88	317	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
648285867	300	40.26	3	297	2	303	4.0e-78	284	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
648285868	1256	59.15	342	1214	1	842	0.0e+00	1176	COG1410	Methionine synthase I, cobalamin-binding domain	842
648285869	463	52.42	140	462	2	331	9.0e-110	390	COG3800	Predicted transcriptional regulator	332
648285870	95	41.05	1	95	1	95	2.0e-21	93.7	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
648285871	495	49.5	1	492	1	474	0.0e+00	482	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
648285873	231	37.99	2	208	9	237	4.0e-44	171	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
648285875	230	30	1	219	7	235	8.0e-29	120	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
648285876	425	58.73	1	424	4	426	0.0e+00	600	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
648285877	431	23.86	40	407	33	365	2.0e-29	123	COG1680	CubicO group peptidase, beta-lactamase class C family	390
648285879	579	35.01	4	577	6	606	6.0e-118	418	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
648285880	599	30.63	158	591	1	443	5.0e-88	318	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
648285881	342	36.36	1	339	10	349	1.0e-63	236	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
648285882	453	31.86	10	446	1	447	7.0e-39	155	COG1538	Outer membrane protein TolC	457
648285883	1041	48.6	1	1028	2	1009	0.0e+00	948	COG0841	Multidrug efflux pump subunit AcrB	1009
648285884	401	32.88	3	369	8	365	3.0e-28	119	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
648285886	200	47.78	1	200	2	199	8.0e-55	206	COG0605	Superoxide dismutase	204
648285887	199	37.24	1	196	18	212	3.0e-41	161	COG2345	Predicted transcriptional regulator, ArsR family	218
648285888	321	24.55	1	317	2	330	4.0e-25	109	COG0673	Predicted dehydrogenase	342
648285889	366	21.47	4	335	10	356	9.0e-24	104	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648285890	200	25.77	1	190	5	192	2.0e-26	112	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
648285891	296	49.66	4	294	1	288	5.0e-69	254	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648285894	539	33.7	1	510	9	528	1.0e-79	291	COG0747	ABC-type transport system, periplasmic component	556
648285895	319	44.27	6	319	1	299	2.0e-92	332	COG2421	Acetamidase/formamidase	305
648285896	599	56.4	17	554	2	539	0.0e+00	672	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
648285898	257	28.88	29	254	15	243	1.0e-29	123	COG1651	Protein-disulfide isomerase	244
648285899	446	28.71	28	445	64	478	6.0e-53	202	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
648285900	381	34.96	8	380	5	392	1.0e-84	307	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
648285901	400	33.62	160	387	33	227	4.0e-38	152	COG0860	N-acetylmuramoyl-L-alanine amidase	231
648285902	845	43	1	790	1	764	0.0e+00	785	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
648285903	320	29.02	4	280	13	296	5.0e-18	85.3	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
648285904	272	48.99	16	262	1	241	4.0e-82	297	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
648285905	277	40	33	277	12	256	4.0e-51	195	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
648285907	342	33.83	12	339	1	329	2.0e-47	183	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
648285908	373	58.58	126	362	1	239	4.0e-90	325	COG1186	Protein chain release factor B	239
648285909	525	27.8	40	500	29	435	4.0e-52	199	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
648285910	268	33.33	10	258	30	284	2.0e-27	116	COG5473	Uncharacterized membrane protein	290
648285913	187	55.06	29	186	5	160	2.0e-47	181	COG0440	Acetolactate synthase, small subunit	163
648285914	342	20.81	17	299	1	286	3.0e-15	76.1	COG3594	Fucose 4-O-acetylase or related acetyltransferase	343
648285915	575	48.21	1	556	7	549	0.0e+00	632	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
648285917	214	41.9	6	209	2	211	7.0e-52	197	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
648285918	473	48.42	14	456	5	448	5.0e-125	441	COG4564	Signal transduction histidine kinase	459
648285919	361	38.38	1	351	1	357	1.0e-82	300	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
648285922	601	38.38	19	599	1	570	0.0e+00	574	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
648285924	398	37.69	14	398	5	392	7.0e-78	284	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
648285926	359	40.44	1	357	1	352	2.0e-93	335	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
648285927	300	28.67	1	296	1	300	8.0e-20	91.5	COG0679	Predicted permease	311
648285928	152	16.55	4	136	10	154	5.0e-06	43.8	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648285930	280	24.91	1	277	18	296	8.0e-37	147	COG0714	MoxR-like ATPase	329
648285931	140	55.83	20	139	1	120	2.0e-25	108	COG1734	RNA polymerase-binding transcription factor DksA	120
648285932	392	31.11	6	384	3	387	1.0e-46	181	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
648285933	152	49.32	4	148	9	154	2.0e-50	191	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
648285934	156	29.73	30	139	35	145	9.0e-14	69.9	COG3871	General stress protein 26 (function unknown)	145
648285935	387	44.56	6	382	1	386	4.0e-91	328	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648285936	524	32.31	19	512	2	521	6.0e-109	388	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
648285937	534	46.27	11	534	1	526	0.0e+00	624	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
648285938	648	57.19	1	642	1	645	0.0e+00	727	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
648285939	221	27.8	1	201	1	200	2.0e-20	92.6	COG0625	Glutathione S-transferase	211
648285941	258	36.33	1	255	4	256	8.0e-36	144	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648285943	121	53.72	1	121	1	121	4.0e-31	126	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
648285944	206	68.29	43	206	5	168	8.0e-76	276	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
648285945	197	51.15	1	173	6	176	8.0e-47	180	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
648285946	410	58.63	18	410	9	398	0.0e+00	611	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
648285948	382	47.53	12	173	2	160	1.0e-52	200	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
648285949	241	37.4	99	229	10	133	1.0e-16	80.1	COG3743	 Predicted 5' DNA nuclease, flap endonuclease-1-like, helix-3-turn-helix (H3TH) domain	133
648285951	431	58.87	1	421	5	424	0.0e+00	643	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
648285955	348	26.15	5	343	1	332	5.0e-34	138	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648285956	487	22.38	95	443	23	368	5.0e-19	89.4	COG4320	Uncharacterized conserved protein, DUF2252 family	410
648285957	342	28.09	25	321	1	293	6.0e-30	125	COG0583	DNA-binding transcriptional regulator, LysR family	297
648285958	288	43.86	5	287	3	287	6.0e-60	224	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
648285959	261	44.19	3	260	10	267	2.0e-52	199	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
648285960	381	26.74	18	380	1	362	2.0e-41	163	COG0687	Spermidine/putrescine-binding periplasmic protein	363
648285961	361	49.03	1	357	3	351	3.0e-111	395	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
648285962	445	43.12	14	438	29	448	1.0e-123	436	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
648285963	308	47.06	1	303	2	298	2.0e-81	296	COG3246	Uncharacterized conserved protein, DUF849 family	298
648285965	340	39.01	27	339	22	311	3.0e-61	229	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
648285967	241	35.22	12	240	12	236	9.0e-42	163	COG2188	DNA-binding transcriptional regulator, GntR family	236
648285968	338	30.42	1	325	16	345	3.0e-53	202	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
648285969	276	27.46	20	251	16	250	7.0e-25	107	COG1082	Sugar phosphate isomerase/epimerase	274
648285970	250	64.02	11	249	3	240	2.0e-115	408	COG1126	ABC-type polar amino acid transport system, ATPase component	240
648285971	276	28.67	1	268	1	275	6.0e-28	118	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
648285972	220	41.98	7	217	11	222	2.0e-44	172	COG0765	ABC-type amino acid transport system, permease component	222
648285973	243	35.16	3	220	10	222	2.0e-33	136	COG0765	ABC-type amino acid transport system, permease component	222
648285974	459	27.25	35	361	34	369	2.0e-26	113	COG2079	2-methylcitrate dehydratase PrpD	453
648285975	499	39.45	6	471	7	459	3.0e-100	359	COG0165	Argininosuccinate lyase	459
648285976	337	28.11	1	337	5	337	1.0e-57	217	COG2222	Fructoselysine-6-P-deglycase FrlB and related proteins with duplicated sugar isomerase (SIS) domain	340
648285977	264	29.5	24	258	35	295	4.0e-29	121	COG0524	Sugar or nucleoside kinase, ribokinase family	311
648285978	357	46.09	1	336	3	343	2.0e-94	339	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
648285979	568	33.99	7	562	1	538	3.0e-69	256	COG1178	ABC-type Fe3+ transport system, permease component	540
648285980	323	35.37	37	320	1	292	1.0e-46	180	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
648285981	332	18.75	78	314	40	248	5.0e-07	48.8	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
648285982	357	55.13	1	339	1	337	2.0e-122	432	COG3839	ABC-type sugar transport system, ATPase component	338
648285983	280	38.63	5	278	11	278	2.0e-49	189	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648285984	323	35.86	32	319	2	290	4.0e-51	195	COG1175	ABC-type sugar transport system, permease component	295
648285985	431	23.27	1	426	10	433	8.0e-40	158	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648285986	151	25	7	130	9	127	2.0e-09	55	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
648285988	293	25.25	4	293	32	317	4.0e-28	118	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
648285990	234	25.96	13	219	7	196	5.0e-11	61.4	COG0406	Broad specificity phosphatase PhoE	208
648285993	2191	27.25	1306	1933	170	788	7.0e-54	207	COG2374	Predicted extracellular nuclease	798
648285994	410	26.9	4	397	2	405	5.0e-33	135	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
648285995	421	33.89	4	419	22	424	2.0e-79	289	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
648285997	425	48.01	47	423	3	378	9.0e-79	287	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648285998	181	29.23	24	152	18	147	1.0e-15	76.5	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648285999	337	31.61	10	337	5	330	2.0e-62	232	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648286000	343	22.85	16	343	1	313	1.0e-25	111	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
648286001	375	30.32	16	350	1	340	5.0e-37	148	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648286002	289	33.68	1	285	4	292	1.0e-34	140	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
648286003	291	40	4	291	27	311	3.0e-38	152	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
648286004	254	43.15	10	251	2	249	5.0e-66	244	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
648286005	236	43.16	3	236	2	234	2.0e-70	258	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
648286006	528	29.63	1	526	7	532	6.0e-73	268	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648286007	152	39.19	5	150	15	159	6.0e-21	93.2	COG2030	Acyl dehydratase	159
648286009	350	18.31	13	349	7	341	3.0e-12	66.5	COG3500	Phage protein D	350
648286010	115	23.97	2	115	1	118	1.0e-10	58.6	COG3293	Transposase	124
648286011	129	31.5	3	128	1	122	2.0e-10	58.2	COG3293	Transposase	124
648286022	340	30.18	5	329	1	303	2.0e-37	150	COG3547	Transposase	303
648286024	101	23.15	1	101	14	118	2.0e-08	50.5	COG3293	Transposase	124
648286025	139	38.85	1	138	3	135	1.0e-35	142	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
648286027	224	39.08	4	224	7	243	1.0e-42	166	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
648286029	92	44.79	1	92	1	96	4.0e-21	93.1	COG5453	Uncharacterized protein	96
648286030	661	58.25	378	660	59	342	3.0e-94	340	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
648286031	653	36.65	3	506	2	498	5.0e-99	355	COG0358	DNA primase (bacterial type)	568
648286033	478	36.86	8	478	1	410	3.0e-96	346	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
648286034	477	18.48	16	190	2	178	5.0e-08	52.8	COG4961	Flp pilus assembly protein TadG	185
648286038	277	39.29	1	277	1	279	3.0e-73	268	COG0077	Prephenate dehydratase	279
648286039	169	49.57	53	165	11	127	7.0e-28	116	COG3474	Cytochrome c2	135
648286040	630	26.44	8	622	5	562	2.0e-70	260	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
648286041	361	67.86	1	360	1	364	0.0e+00	557	COG4174	ABC-type microcin C transport system, permease component YejB	364
648286042	406	58.74	41	405	4	341	8.0e-128	450	COG4239	ABC-type microcin C transport system, permease component YejE	341
648286043	530	59.7	2	529	4	534	0.0e+00	756	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
648286044	442	30.77	9	435	7	416	1.0e-97	350	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
648286045	248	33.33	28	231	12	214	4.0e-31	128	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
648286046	116	52.59	1	115	1	116	2.0e-31	127	COG5507	Uncharacterized  conserved protein YbaA, DUF1428 family	117
648286048	537	68.53	54	536	1	482	0.0e+00	690	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
648286049	242	62.93	6	237	2	225	7.0e-96	343	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
648286050	66	36	6	55	3	52	7.0e-09	52.1	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
648286051	293	28.93	60	216	3	146	1.0e-14	73.8	COG2010	Cytochrome c, mono- and diheme variants	150
648286053	291	28.18	7	288	1	291	2.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
648286054	477	33.58	20	426	1	370	8.0e-74	271	COG0348	Polyferredoxin	386
648286055	153	34.62	2	152	8	162	4.0e-20	90.8	COG5456	Nitrogen fixation protein FixH	166
648286057	580	43.5	1	580	114	708	0.0e+00	540	COG2217	Cation transport ATPase	713
648286058	53	43.4	1	53	1	53	2.0e-09	53.7	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
648286059	526	43.36	1	525	6	535	0.0e+00	493	COG2303	Choline dehydrogenase or related flavoprotein	542
648286060	152	45.39	1	152	4	154	8.0e-35	139	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648286061	370	62.97	1	370	1	370	0.0e+00	527	COG0686	Alanine dehydrogenase	371
648286062	295	37.59	1	289	8	295	2.0e-66	246	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
648286063	140	47.14	1	140	3	129	1.0e-28	119	COG1970	Large-conductance mechanosensitive channel	130
648286065	341	62.02	2	337	3	339	3.0e-120	425	COG1077	Actin-like ATPase involved in cell morphogenesis	342
648286066	302	32.2	14	268	8	268	4.0e-39	155	COG1792	Cell shape-determining protein MreC	284
648286068	625	30.79	3	594	15	599	9.0e-109	387	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
648286069	379	39.67	20	379	13	374	9.0e-74	270	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
648286070	310	34.07	12	310	9	324	1.0e-51	196	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
648286071	131	34.96	5	126	14	134	3.0e-15	74.3	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
648286073	223	40.62	158	221	2	65	4.0e-12	65	COG2771	DNA-binding transcriptional regulator, CsgD family	65
648286075	428	28.27	37	410	1	326	7.0e-48	185	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
648286076	665	45.17	19	502	71	548	0.0e+00	496	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
648286078	234	55.17	1	232	2	233	3.0e-89	321	COG0813	Purine-nucleoside phosphorylase	236
648286079	281	36.9	5	273	11	263	2.0e-56	212	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
648286081	228	48.52	1	228	1	237	3.0e-67	248	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
648286082	249	44.58	2	246	1	249	3.0e-64	238	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
648286083	326	37.31	3	324	1	313	6.0e-40	158	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
648286084	306	41.29	1	305	1	293	5.0e-39	154	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
648286085	378	30.7	14	352	2	356	2.0e-39	156	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648286088	258	24.56	1	247	11	291	6.0e-16	78.2	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
648286089	259	51.52	30	259	5	232	7.0e-84	303	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
648286092	601	53.2	7	578	3	561	0.0e+00	620	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
648286093	123	26.96	9	122	3	117	9.0e-09	52.5	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
648286094	131	35.66	7	131	1	127	2.0e-10	58	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
648286096	343	30.07	1	149	8	156	5.0e-14	72.4	COG2030	Acyl dehydratase	159
648286097	67	66.18	1	67	3	70	4.0e-24	102	COG5515	Uncharacterized protein	70
648286099	283	41.55	10	283	1	283	1.0e-61	229	COG2301	Citrate lyase beta subunit	283
648286101	320	47.27	4	313	1	308	5.0e-103	367	COG0039	Malate/lactate dehydrogenase	313
648286103	397	56.64	1	397	1	386	0.0e+00	522	COG0045	Succinyl-CoA synthetase, beta subunit	387
648286105	294	67.24	1	293	1	290	5.0e-121	427	COG0074	Succinyl-CoA synthetase, alpha subunit	293
648286106	990	53.41	7	987	1	906	0.0e+00	1282	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
648286107	512	51.22	108	511	1	404	1.0e-113	403	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
648286109	130	26.27	13	130	9	125	3.0e-09	54.5	COG3686	Uncharacterized conserved protein, MAPEG superfamily	125
648286110	129	36	5	129	1	125	3.0e-14	71.1	COG3686	Uncharacterized conserved protein, MAPEG superfamily	125
648286111	464	51.53	1	454	2	454	0.0e+00	512	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
648286113	200	26.95	1	159	1	163	6.0e-21	94.3	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
648286114	244	28.37	36	243	26	235	2.0e-21	96.5	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
648286116	252	68.63	1	252	1	255	1.0e-111	396	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
648286117	103	53.85	3	93	1	91	4.0e-22	96.4	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
648286118	155	45.99	1	137	2	136	1.0e-39	155	COG1832	Predicted CoA-binding protein	140
648286119	763	35.76	8	757	8	731	0.0e+00	512	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
648286120	375	27.39	18	369	23	392	6.0e-37	148	COG0019	Diaminopimelate decarboxylase	394
648286121	152	32	6	151	1	150	4.0e-18	84	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648286122	354	39.64	51	321	12	262	1.0e-51	197	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
648286124	1025	43.04	3	1023	1	877	0.0e+00	1011	COG0525	Valyl-tRNA synthetase	877
648286125	255	35.74	1	251	1	251	5.0e-31	128	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648286126	201	27.64	1	199	6	203	2.0e-26	112	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
648286128	482	33.94	3	481	2	487	2.0e-75	277	COG0168	Trk-type K+ transport system, membrane component	499
648286130	363	28.67	72	337	4	277	1.0e-43	170	COG1469	GTP cyclohydrolase FolE2	289
648286131	392	43.73	4	391	6	394	1.0e-119	423	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
648286132	623	38.77	1	416	4	397	4.0e-59	223	COG0475	Kef-type K+ transport system, membrane component KefB	397
648286133	169	50.62	5	164	1	160	2.0e-49	188	COG1329	RNA polymerase-interacting regulator, CarD/CdnL/TRCF family	166
648286134	112	40.91	4	65	5	68	2.0e-07	47.5	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
648286135	124	47.78	4	92	5	93	9.0e-21	92.3	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
648286139	323	26.77	10	313	1	295	5.0e-37	148	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
648286140	339	21.03	6	328	19	424	1.0e-29	123	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
648286141	530	31.76	71	525	12	442	3.0e-62	233	COG1793	ATP-dependent DNA ligase	444
648286143	608	35.57	21	607	6	596	0.0e+00	507	COG1164	Oligoendopeptidase F	598
648286145	89	29.41	1	77	36	120	8.0e-08	48.9	COG1734	RNA polymerase-binding transcription factor DksA	120
648286146	171	42.95	23	171	8	161	9.0e-45	173	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
648286147	81	32.35	12	79	2	69	8.0e-09	51.8	COG2841	Uncharacterized conserved protein YdcH, DUF465 family	72
648286148	205	34.25	3	139	42	185	5.0e-15	74.5	COG1525	Endonuclease YncB, thermonuclease family	192
648286149	225	36.6	2	222	10	244	3.0e-37	148	COG3346	Cytochrome oxidase assembly protein ShyY1	252
648286150	463	32.19	1	459	1	410	3.0e-97	349	COG0498	Threonine synthase	411
648286151	420	37.2	3	412	17	438	3.0e-85	309	COG0612	Predicted Zn-dependent peptidase	438
648286152	194	32.43	6	189	1	184	4.0e-23	101	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648286153	275	15.42	57	263	7	258	3.0e-11	62.5	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
648286154	471	36.73	24	470	14	457	5.0e-77	282	COG0277	FAD/FMN-containing dehydrogenase	459
648286158	286	31.44	1	263	1	259	4.0e-29	122	COG3745	Flp pilus assembly protein CpaB	276
648286159	471	34.33	7	469	1	453	5.0e-90	325	COG4964	Flp pilus assembly protein, secretin CpaC	455
648286160	221	29.79	2	178	3	189	4.0e-24	104	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
648286161	410	28.46	135	399	84	341	4.0e-24	106	COG4963	Flp pilus assembly protein, ATPase CpaE	366
648286162	489	54.47	90	447	1	353	9.0e-119	420	COG4962	Pilus assembly protein, ATPase of CpaF family	355
648286163	321	26.75	8	321	2	309	2.0e-38	153	COG4965	Flp pilus assembly protein TadB	309
648286164	323	24.68	18	321	10	320	3.0e-18	86	COG2064	Pilus assembly protein TadC	320
648286166	286	21.2	7	222	6	217	3.0e-10	59.6	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
648286167	165	25.5	8	150	3	151	2.0e-06	45.6	COG4960	Flp pilus assembly protein, protease CpaA	168
648286168	233	21.7	28	225	10	210	9.0e-10	57.2	COG2755	Lysophospholipase L1 or related esterase	216
648286172	400	35.42	19	384	15	371	1.0e-76	280	COG3328	Transposase (or an inactivated derivative)	379
648286173	362	23.77	45	362	5	299	4.0e-24	105	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
648286174	398	33.5	9	397	4	394	8.0e-56	211	COG2814	Predicted arabinose efflux permease, MFS family	394
648286176	204	26.92	4	203	1	206	2.0e-18	86	COG0625	Glutathione S-transferase	211
648286177	435	32.11	54	435	2	377	8.0e-57	214	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648286178	168	23.49	1	166	5	164	2.0e-10	59.2	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648286179	333	24.92	1	292	2	299	2.0e-29	123	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648286180	194	42.02	1	185	1	188	7.0e-47	180	COG0066	3-isopropylmalate dehydratase small subunit	191
648286181	463	48.6	3	459	4	423	0.0e+00	525	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
648286182	268	34.35	14	242	8	236	2.0e-41	162	COG2188	DNA-binding transcriptional regulator, GntR family	236
648286184	564	40.65	5	556	1	549	0.0e+00	465	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
648286185	686	40.03	7	685	4	673	0.0e+00	527	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
648286186	205	29.63	6	185	1	183	9.0e-22	96.8	COG1335	Nicotinamidase-related amidase	205
648286187	288	40.65	1	278	8	282	1.0e-62	233	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
648286188	454	25.22	12	453	4	408	1.0e-24	107	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
648286190	666	46.46	6	658	3	684	0.0e+00	637	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
648286192	345	49.55	4	333	3	331	4.0e-94	338	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
648286193	164	47.53	8	164	5	161	1.0e-45	175	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
648286195	202	47.37	1	171	3	166	2.0e-24	105	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
648286197	101	60.4	1	101	1	100	8.0e-23	98.6	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
648286198	718	48.8	4	495	3	474	9.0e-122	431	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
648286200	516	53.36	4	504	5	493	0.0e+00	520	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
648286201	480	46.22	3	478	2	474	2.0e-92	333	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
648286202	248	35.27	12	248	1	235	8.0e-43	167	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
648286203	259	42.29	1	253	1	251	4.0e-63	234	COG1521	Pantothenate kinase type III	251
648286204	555	36.14	3	551	6	554	3.0e-117	416	COG0595	mRNA degradation ribonuclease J1/J2	555
648286206	395	48.84	5	388	3	388	1.0e-118	420	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
648286207	345	35.88	5	344	1	350	1.0e-69	257	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
648286208	150	37.14	44	147	20	124	1.0e-11	62.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
648286209	233	51.91	1	233	3	237	1.0e-78	286	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
648286210	256	44.4	1	246	1	250	3.0e-76	278	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
648286211	618	36.27	1	291	3	296	7.0e-41	162	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
648286212	402	31.78	20	379	3	363	4.0e-41	162	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648286213	356	27.02	1	340	20	360	5.0e-38	151	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
648286216	287	35.09	5	262	2	252	3.0e-29	122	COG2122	Uncharacterized protein, UPF0280 family, ApbE superfamily	256
648286218	282	40	3	272	6	280	1.0e-49	190	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
648286219	905	31.9	167	898	6	729	2.0e-128	453	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
648286220	702	40.5	28	697	6	672	0.0e+00	534	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
648286221	558	40.93	3	558	2	549	0.0e+00	559	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
648286222	923	60.26	8	922	1	861	0.0e+00	1198	COG1048	Aconitase A	861
648286223	235	39.57	12	232	25	253	1.0e-48	186	COG5429	Uncharacterized protein	261
648286224	310	27.82	23	301	23	306	1.0e-39	157	COG1560	Lauroyl/myristoyl acyltransferase	308
648286225	350	25.38	16	343	7	332	2.0e-27	117	COG1536	Flagellar motor switch protein FliG	339
648286227	434	48.17	1	434	1	438	0.0e+00	509	COG0015	Adenylosuccinate lyase	438
648286229	433	36.26	7	425	11	417	2.0e-67	249	COG4949	Uncharacterized membrane-anchored protein	424
648286233	457	24.84	3	457	1	408	5.0e-51	195	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648286236	407	44.97	1	395	1	388	2.0e-114	405	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
648286237	541	19.54	26	327	1	262	4.0e-15	76.7	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
648286238	377	57.98	12	368	1	357	0.0e+00	501	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
648286239	707	29.89	31	282	2	277	5.0e-31	129	COG0515	Serine/threonine protein kinase	384
648286241	382	28.61	2	381	3	346	4.0e-19	89.4	COG3515	Predicted component of the type VI protein secretion system	346
648286242	179	44.57	2	176	1	168	5.0e-45	173	COG3516	Predicted component of the type VI protein secretion system	169
648286243	502	55.27	1	501	1	494	0.0e+00	695	COG3517	Predicted component of the type VI protein secretion system	495
648286244	169	22.22	1	156	1	153	7.0e-15	73.8	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
648286245	217	33.14	46	216	4	157	2.0e-18	85.8	COG3518	Predicted component of the type VI protein secretion system	157
648286246	625	38.52	1	625	1	621	0.0e+00	484	COG3519	Type VI protein secretion system component VasA	621
648286247	354	33.12	22	332	19	323	2.0e-55	209	COG3520	Predicted component of the type VI protein secretion system	335
648286249	150	26.58	1	150	1	157	4.0e-19	87.7	COG3521	Predicted component of the type VI protein secretion system	159
648286250	444	36.75	1	444	1	446	2.0e-102	366	COG3522	Predicted component of the type VI protein secretion system	446
648286251	452	34.57	37	278	21	262	2.0e-45	177	COG3455	Type VI protein secretion system component VasF	262
648286252	1184	37.85	3	1181	1	1184	0.0e+00	828	COG3523	Type VI protein secretion system component VasK	1188
648286255	200	28.49	9	194	4	176	2.0e-26	111	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
648286256	178	37.65	19	176	4	164	1.0e-28	119	COG3153	Predicted N-acetyltransferase YhbS	171
648286258	744	45.64	13	744	5	747	0.0e+00	701	COG3605	Signal transduction protein containing GAF and PtsI domains	756
648286259	412	40.35	1	409	1	447	1.0e-111	396	COG0527	Aspartokinase	447
648286261	214	29.11	1	191	6	211	1.0e-20	93.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648286262	144	43.17	1	139	1	138	7.0e-32	129	COG5319	Uncharacterized protein	142
648286264	403	36.72	1	383	2	402	7.0e-74	271	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
648286265	194	38.1	33	176	1	146	8.0e-24	103	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
648286266	351	26.22	47	347	39	354	3.0e-30	125	COG4188	Predicted dienelactone hydrolase	365
648286271	732	64.01	28	691	1	663	0.0e+00	1057	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
648286273	210	63.51	3	210	5	212	5.0e-61	227	COG3571	Predicted hydrolase of the alpha/beta-hydrolase fold	213
648286274	634	38.33	289	513	1	227	1.0e-46	181	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
648286276	355	24.41	34	355	14	353	1.0e-27	117	COG4782	Esterase/lipase superfamily enzyme	377
648286277	514	31.15	7	459	3	404	2.0e-57	217	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
648286278	164	33.33	2	157	29	183	3.0e-09	54.8	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
648286280	255	25.64	135	250	22	137	5.0e-12	65.1	COG3187	Heat shock protein HslJ	142
648286281	223	21.23	5	209	1	212	9.0e-23	100	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
648286283	480	31.96	2	426	25	443	1.0e-59	224	COG3119	Arylsulfatase A or related enzyme	475
648286285	304	23.55	1	256	9	273	3.0e-09	56.2	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
648286288	463	53.63	2	454	7	461	0.0e+00	599	COG0055	FoF1-type ATP synthase, beta subunit	468
648286289	154	26.92	3	131	2	129	1.0e-06	46.4	COG0355	FoF1-type ATP synthase, epsilon subunit	135
648286292	230	29.19	22	215	34	242	1.0e-29	123	COG0356	FoF1-type ATP synthase, membrane subunit a	246
648286293	82	48.72	3	80	2	79	2.0e-06	44.4	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
648286294	244	26.88	1	160	2	161	9.0e-10	57.6	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
648286295	510	50.21	15	498	13	496	0.0e+00	573	COG0056	FoF1-type ATP synthase, alpha subunit	504
648286296	281	22.3	7	279	2	283	5.0e-25	108	COG0224	FoF1-type ATP synthase, gamma subunit	287
648286297	379	47.08	10	366	6	362	1.0e-96	346	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
648286298	460	43.2	4	455	1	449	0.0e+00	517	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
648286299	427	25.29	9	424	2	409	4.0e-46	179	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648286300	342	35.19	28	341	23	313	4.0e-60	225	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
648286301	239	33.03	18	237	10	228	8.0e-33	134	COG1802	DNA-binding transcriptional regulator, GntR family	230
648286302	256	36.74	12	224	7	214	6.0e-40	157	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
648286303	515	32.22	3	514	18	554	3.0e-79	289	COG0747	ABC-type transport system, periplasmic component	556
648286304	325	49.84	3	321	1	313	1.0e-84	306	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648286305	266	48.68	1	263	25	289	4.0e-62	231	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648286306	537	54.65	1	530	2	537	0.0e+00	641	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
648286307	299	34.3	4	279	11	286	9.0e-56	210	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
648286308	464	30.33	2	460	1	470	5.0e-74	272	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
648286309	430	46.3	4	430	31	457	3.0e-114	405	COG0513	Superfamily II DNA and RNA helicase	513
648286310	504	54.67	16	504	1	482	0.0e+00	686	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
648286313	849	34.97	1	842	4	858	0.0e+00	554	COG0308	Aminopeptidase N	859
648286316	291	25.34	3	285	1	292	4.0e-16	78.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
648286317	215	51.24	1	198	2	202	8.0e-47	180	COG1279	Arginine exporter protein ArgO	202
648286320	362	50.68	1	361	11	371	2.0e-116	412	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
648286321	214	27.7	7	209	39	242	6.0e-18	84.1	COG1651	Protein-disulfide isomerase	244
648286322	169	26.16	4	169	18	181	2.0e-14	72	COG5389	Uncharacterized protein	181
648286323	348	45.06	9	346	14	341	8.0e-97	347	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
648286325	130	46.09	2	129	7	134	2.0e-36	144	COG0295	Cytidine deaminase	134
648286326	429	46.54	1	429	2	434	6.0e-120	424	COG0213	Thymidine phosphorylase	435
648286327	401	49.02	1	401	2	393	2.0e-123	436	COG1015	Phosphopentomutase	397
648286328	333	37.2	9	333	8	339	4.0e-70	258	COG1816	Adenosine deaminase	345
648286330	458	40.79	58	458	22	402	3.0e-92	332	COG1115	Na+/alanine symporter	452
648286331	145	26.28	12	145	15	151	1.0e-05	42.3	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
648286333	139	49.68	1	139	2	154	6.0e-45	172	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
648286334	90	35.87	1	89	1	92	4.0e-15	73	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
648286335	320	49.39	1	320	2	329	9.0e-90	323	COG0240	Glycerol-3-phosphate dehydrogenase	329
648286336	359	53.04	5	348	2	340	1.0e-112	399	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
648286337	248	24.7	8	235	4	247	1.0e-14	73.5	COG1587	Uroporphyrinogen-III synthase	248
648286339	511	27.71	5	509	1	506	1.0e-60	228	COG3898	Uncharacterized membrane-anchored protein	531
648286342	336	23.74	6	323	35	369	2.0e-19	90.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648286345	405	21.74	5	405	13	425	2.0e-12	67.4	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
648286346	405	21.96	92	301	47	239	3.0e-15	76.7	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
648286347	812	33.94	292	567	72	335	8.0e-37	149	COG0642	Signal transduction histidine kinase	336
648286348	172	38.55	7	171	2	154	1.0e-31	129	COG3915	Uncharacterized protein	155
648286349	459	45.1	258	459	33	226	1.0e-57	217	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
648286350	204	41.63	1	203	1	208	9.0e-40	156	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
648286351	490	18.76	47	483	18	457	9.0e-14	72	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
648286355	166	42.44	3	166	1	171	2.0e-39	154	COG3807	SH3-like domain	171
648286356	328	44.34	4	325	1	323	5.0e-92	331	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
648286358	521	51.09	7	416	1	409	1.0e-118	420	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
648286361	400	24.94	1	399	1	380	3.0e-34	139	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648286363	454	22.8	13	450	3	445	1.0e-15	78.2	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
648286364	2152	38.33	6	1067	2	1057	0.0e+00	722	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
648286365	340	25.89	1	304	1	291	6.0e-38	151	COG1216	Glycosyltransferase, GT2 family	305
648286368	441	15.85	4	371	11	458	2.0e-09	57.4	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
648286369	380	25.46	168	379	33	238	3.0e-18	86.7	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
648286370	223	26.09	25	198	49	232	4.0e-16	78.4	COG3300	MHYT domain, NO-binding membrane sensor	236
648286371	308	21.93	88	308	17	237	4.0e-14	72.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648286374	317	38.24	4	309	2	303	8.0e-58	217	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
648286375	445	39.29	3	434	11	457	1.0e-102	366	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
648286376	408	28.6	1	407	23	445	2.0e-52	200	COG4325	Uncharacterized membrane protein	464
648286378	145	37.01	1	126	15	140	5.0e-23	100	COG1959	DNA-binding transcriptional regulator, IscR family	150
648286379	375	43.9	1	375	2	376	2.0e-97	349	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
648286380	119	54.55	1	119	9	129	3.0e-34	136	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
648286381	948	57.4	443	916	12	496	0.0e+00	695	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
648286384	489	26.98	2	489	29	553	8.0e-69	254	COG0747	ABC-type transport system, periplasmic component	556
648286385	251	34.02	9	249	1	240	3.0e-39	155	COG1414	DNA-binding transcriptional regulator, IclR family	246
648286386	131	39.39	5	130	7	138	2.0e-28	118	COG5573	Predicted nucleic acid-binding protein, contains PIN domain	142
648286388	946	31.95	26	522	9	459	1.0e-61	232	COG0277	FAD/FMN-containing dehydrogenase	459
648286389	300	33.11	10	299	1	288	2.0e-28	119	COG0583	DNA-binding transcriptional regulator, LysR family	297
648286390	296	26.04	13	293	4	282	7.0e-13	68.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648286391	375	38.1	3	359	1	352	2.0e-91	329	COG1377	Flagellar biosynthesis protein FlhB	363
648286392	251	32.23	4	244	5	245	2.0e-26	113	COG1684	Flagellar biosynthesis protein FliR	258
648286393	697	46.86	16	696	13	694	0.0e+00	743	COG1298	Flagellar biosynthesis pathway, component FlhA	696
648286395	89	44.05	1	84	1	84	1.0e-11	61.3	COG1987	Flagellar biosynthesis protein FliQ	89
648286396	109	31.43	6	109	2	105	7.0e-08	49.2	COG1677	Flagellar hook-basal body complex protein FliE	105
648286397	136	41.3	2	136	1	137	8.0e-34	135	COG1558	Flagellar basal body rod protein FlgC	137
648286398	133	29.13	9	131	8	132	9.0e-17	79.2	COG1815	Flagellar basal body rod protein FlgB	133
648286399	418	51.97	1	406	35	437	0.0e+00	503	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
648286401	315	27.27	50	277	2	224	8.0e-16	78	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
648286402	391	32.23	112	381	3	258	4.0e-47	182	COG1192	Cellulose biosynthesis protein BcsQ	259
648286405	298	30.85	11	292	3	261	6.0e-49	188	COG1291	Flagellar motor component MotA	266
648286407	221	24.24	9	219	4	229	7.0e-14	71.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648286409	142	37.1	9	132	15	136	1.0e-23	102	COG4957	Predicted transcriptional regulator	148
648286410	329	27.1	10	316	1	240	6.0e-39	154	COG1360	Flagellar motor protein MotB	244
648286412	249	26.22	1	238	68	331	8.0e-24	104	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
648286414	223	35.27	1	222	1	221	1.0e-27	116	COG1843	Flagellar hook assembly protein FlgD	222
648286416	253	34.27	3	250	1	230	4.0e-48	184	COG2063	Flagellar basal body L-ring protein FlgH	230
648286417	220	22.58	5	218	4	218	2.0e-16	79.6	COG1261	Flagella basal body P-ring formation protein FlgA	220
648286418	261	48.68	1	261	2	264	2.0e-71	262	COG4786	Flagellar basal body rod protein FlgG	265
648286419	249	33.08	1	246	1	265	2.0e-43	169	COG4786	Flagellar basal body rod protein FlgG	265
648286421	433	31.49	5	433	3	423	7.0e-55	208	COG1749	Flagellar hook protein FlgE	423
648286422	470	24.82	1	469	1	550	7.0e-39	155	COG1256	Flagellar hook-associated protein FlgK	552
648286423	353	21.88	9	353	4	358	1.0e-15	77.8	COG1344	Flagellin and related hook-associated protein FlgL	360
648286424	258	30.9	3	228	2	228	2.0e-26	113	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648286425	370	52.99	3	370	2	365	8.0e-107	380	COG1706	Flagellar basal body P-ring protein FlgI	365
648286428	330	21.45	3	330	2	360	2.0e-25	109	COG1344	Flagellin and related hook-associated protein FlgL	360
648286429	309	20.33	3	309	2	360	2.0e-21	96.3	COG1344	Flagellin and related hook-associated protein FlgL	360
648286430	145	31.4	5	123	5	114	1.0e-10	59.6	COG5442	Flagellar biosynthesis regulator FlaF	115
648286431	136	32.82	1	130	3	132	1.0e-19	88.9	COG5443	Flagellar biosynthesis regulator FlbT	148
648286433	354	32.52	24	350	9	337	6.0e-57	215	COG1536	Flagellar motor switch protein FliG	339
648286434	282	48.7	7	275	5	247	1.0e-70	260	COG1338	Flagellar biosynthetic protein FliP	248
648286437	535	31.67	1	532	38	545	7.0e-80	291	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
648286439	313	25.17	22	311	41	329	2.0e-39	156	COG1868	Flagellar motor switch protein FliM	332
648286441	205	24.31	52	195	50	186	7.0e-09	54.3	COG3334	Flagellar motility protein MotE, a chaperone for MotC folding	192
648286443	407	24.61	12	383	16	384	6.0e-31	128	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
648286444	400	36.41	1	392	5	396	2.0e-79	289	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
648286445	386	39.64	1	382	1	389	7.0e-82	297	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648286447	144	30.71	8	140	18	157	4.0e-13	67.4	COG2030	Acyl dehydratase	159
648286448	309	27.21	5	309	2	296	6.0e-38	151	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
648286449	307	27.33	8	306	7	297	3.0e-39	155	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
648286451	308	26.91	1	297	1	297	7.0e-26	111	COG0583	DNA-binding transcriptional regulator, LysR family	297
648286452	229	31.22	4	224	36	254	1.0e-31	129	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
648286453	190	33.33	21	188	2	168	4.0e-21	95	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648286454	425	45.79	45	424	1	378	1.0e-86	313	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648286455	321	36.79	6	318	9	326	2.0e-68	253	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648286456	469	38.19	2	452	1	428	7.0e-96	344	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
648286459	619	42.86	1	519	3	530	0.0e+00	493	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
648286460	140	58.96	2	135	1	134	2.0e-51	194	COG0105	Nucleoside diphosphate kinase	135
648286462	56	69.81	1	52	4	56	4.0e-10	56.3	COG0401	Uncharacterized membrane protein YqaE, homolog of Blt101, UPF0057 family	56
648286464	208	36.42	37	208	13	182	4.0e-23	101	COG1268	Biotin transporter BioY	184
648286467	270	39.11	2	243	10	252	5.0e-48	184	COG2951	Membrane-bound lytic murein transglycosylase B	343
648286469	468	45.68	1	468	1	443	0.0e+00	501	COG0174	Glutamine synthetase	443
648286470	112	75.89	1	112	1	112	1.0e-40	158	COG0347	Nitrogen regulatory protein PII	112
648286471	536	42.34	266	533	24	282	6.0e-49	188	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
648286472	504	46.15	22	500	1	462	0.0e+00	477	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
648286474	400	29.69	13	389	10	388	1.0e-63	237	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
648286475	140	42.86	25	136	5	116	3.0e-31	127	COG1733	DNA-binding transcriptional regulator, HxlR family	120
648286476	289	36.33	6	276	2	275	2.0e-28	120	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
648286477	174	35.29	13	162	6	149	2.0e-18	85.4	COG2236	Hypoxanthine phosphoribosyltransferase	192
648286478	255	65.73	1	248	12	259	8.0e-112	396	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
648286479	201	49.23	8	201	22	214	2.0e-63	235	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
648286480	180	32.81	17	80	4	67	1.0e-11	62.8	COG1278	Cold shock protein, CspA family	67
648286481	158	42.4	27	151	3	124	2.0e-30	125	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
648286483	1215	20.24	8	721	3	583	2.0e-79	291	COG0209	Ribonucleotide reductase alpha subunit	696
648286485	311	27.01	1	309	2	307	5.0e-23	101	COG0679	Predicted permease	311
648286486	503	30.96	14	499	8	523	4.0e-76	278	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648286487	206	25.45	25	133	1	110	2.0e-08	52.7	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
648286489	429	32.61	154	429	80	308	3.0e-22	99	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
648286490	336	32.92	18	336	13	295	5.0e-38	152	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
648286491	274	47.26	41	274	2	237	8.0e-76	276	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
648286492	256	41.87	2	247	8	250	7.0e-74	270	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
648286493	395	31.08	14	332	1	322	2.0e-30	127	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648286494	332	39.77	2	328	59	393	1.0e-68	253	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
648286495	336	48	8	331	2	326	9.0e-98	350	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
648286496	440	61.31	2	429	19	445	0.0e+00	643	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
648286498	504	35.45	1	487	13	477	6.0e-123	434	COG0380	Trehalose-6-phosphate synthase	486
648286499	258	21.27	17	253	5	264	1.0e-16	80.5	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
648286500	346	46.06	1	330	9	329	1.0e-97	350	COG0240	Glycerol-3-phosphate dehydrogenase	329
648286501	303	47.72	11	294	3	282	2.0e-83	302	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
648286503	296	41.81	1	296	1	290	1.0e-66	246	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
648286504	213	52.36	2	192	1	188	4.0e-63	234	COG0194	Guanylate kinase	191
648286505	173	51.45	1	173	2	174	6.0e-59	220	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
648286509	346	23.81	1	328	19	315	4.0e-33	135	COG0226	ABC-type phosphate transport system, periplasmic component	318
648286510	484	42.26	177	483	4	310	2.0e-68	253	COG0573	ABC-type phosphate transport system, permease component	310
648286511	452	36.98	189	452	35	292	1.0e-63	237	COG0581	ABC-type phosphate transport system, permease component	292
648286512	265	64.17	12	265	2	253	7.0e-126	443	COG1117	ABC-type phosphate transport system, ATPase component	253
648286513	241	42.06	7	239	8	240	6.0e-41	161	COG0704	Phosphate uptake regulator	240
648286514	229	50.66	6	228	1	225	2.0e-62	232	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648286516	255	55.51	3	247	1	245	3.0e-101	361	COG0052	Ribosomal protein S2	252
648286517	291	55.67	1	291	2	296	9.0e-84	303	COG0264	Translation elongation factor EF-Ts	296
648286519	147	57.64	4	147	3	146	5.0e-55	206	COG0757	3-dehydroquinate dehydratase	146
648286520	297	26.53	6	292	1	289	3.0e-22	99.5	COG0524	Sugar or nucleoside kinase, ribokinase family	311
648286521	305	60.8	2	302	9	309	9.0e-109	386	COG2313	Pseudouridine-5'-phosphate glycosidase (pseudoU degradation)	310
648286522	183	42.51	16	182	4	168	8.0e-43	166	COG2928	Uncharacterized membrane protein	222
648286523	271	45.69	11	270	4	265	2.0e-57	215	COG0345	Pyrroline-5-carboxylate reductase	266
648286524	112	33.33	1	111	8	123	7.0e-16	75.8	COG0073	tRNA-binding EMAP/Myf domain	123
648286525	319	43.17	3	317	4	321	9.0e-85	307	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
648286526	146	62.07	1	144	1	145	9.0e-55	205	COG1490	D-Tyr-tRNAtyr deacylase	145
648286527	299	31.45	1	298	1	300	4.0e-34	138	COG0524	Sugar or nucleoside kinase, ribokinase family	311
648286532	378	33.55	1	302	1	304	3.0e-59	222	COG4260	Membrane protease subunit, stomatin/prohibitin family, contains C-terminal Zn-ribbon domain	345
648286533	141	24.09	1	131	1	135	1.0e-12	65.7	COG1017	Hemoglobin-like flavoprotein	150
648286535	400	32.46	8	384	6	382	2.0e-56	213	COG3853	Uncharacterized conserved protein YaaN involved in tellurite resistance	386
648286540	283	46.32	23	245	4	234	3.0e-60	225	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
648286541	145	51.06	1	141	12	152	6.0e-40	156	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
648286543	292	31.8	3	290	2	300	2.0e-52	199	COG2264	Ribosomal protein L11 methylase PrmA	300
648286545	96	44	47	96	12	61	6.0e-07	45.7	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
648286546	163	57.33	4	153	1	150	5.0e-50	190	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
648286547	224	40	1	220	1	200	5.0e-50	190	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
648286548	341	63.22	5	331	2	330	0.0e+00	494	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
648286553	310	40.39	1	304	2	292	1.0e-68	253	COG1131	ABC-type multidrug transport system, ATPase component	293
648286556	344	50	13	323	6	314	4.0e-103	368	COG0180	Tryptophanyl-tRNA synthetase	314
648286557	228	24.34	6	227	9	223	2.0e-08	53.2	COG0705	Membrane associated serine protease, rhomboid family	228
648286558	495	20.34	3	468	62	432	2.0e-25	110	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
648286559	515	37.89	1	502	4	515	2.0e-80	293	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
648286560	483	38.66	1	482	4	497	3.0e-106	379	COG1070	Sugar (pentulose or hexulose) kinase	502
648286564	230	32.87	11	226	11	223	1.0e-41	163	COG1451	Predicted metal-dependent hydrolase	223
648286565	216	29.03	1	215	4	219	2.0e-23	102	COG1802	DNA-binding transcriptional regulator, GntR family	230
648286566	410	25.68	59	330	52	338	9.0e-12	65	COG1566	Multidrug resistance efflux pump	352
648286567	787	20.81	425	784	15	406	1.0e-10	62.6	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
648286568	235	47.77	7	224	3	226	2.0e-74	272	COG1136	ABC-type lipoprotein export system, ATPase component	226
648286570	272	42.28	21	266	23	266	1.0e-64	240	COG1526	Formate dehydrogenase assembly factor FdhD	266
648286571	973	45.32	18	968	1	964	0.0e+00	1224	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
648286572	506	51.2	91	503	6	421	0.0e+00	539	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
648286573	155	38.96	4	153	2	155	7.0e-41	159	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
648286574	296	29.86	1	286	2	285	3.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
648286575	954	40.24	1	586	1	578	1.0e-117	418	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
648286576	115	45.79	1	104	1	107	2.0e-17	81	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
648286577	547	31.65	1	508	1	499	1.0e-57	217	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
648286578	163	39.62	5	163	1	158	2.0e-30	124	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
648286579	90	37.08	1	89	1	89	8.0e-10	55.5	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
648286580	129	40.45	6	94	1	89	2.0e-19	88.4	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
648286581	166	32.53	1	159	1	163	2.0e-29	121	COG2062	Phosphohistidine phosphatase SixA	163
648286583	297	50.38	29	286	2	264	3.0e-76	278	COG0548	Acetylglutamate kinase	265
648286584	217	48.7	22	214	1	193	1.0e-62	232	COG0218	GTP-binding protein EngB required for normal cell division	200
648286585	246	24.91	3	243	2	259	4.0e-21	95	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
648286586	611	35.91	271	601	6	314	7.0e-70	258	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
648286587	515	39.45	244	499	1	253	7.0e-60	225	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
648286588	328	30.98	57	308	1	243	8.0e-47	181	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
648286589	178	40.11	5	175	2	179	4.0e-28	117	COG2032	Cu/Zn superoxide dismutase	179
648286590	69	54.55	3	68	14	79	9.0e-21	91.6	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
648286591	120	38.53	8	115	3	108	8.0e-13	65.7	COG0594	RNase P protein component	117
648286593	251	27.84	27	202	9	183	5.0e-18	85	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
648286594	368	20.88	7	365	12	362	1.0e-27	117	COG0687	Spermidine/putrescine-binding periplasmic protein	363
648286595	366	46.54	6	365	1	352	2.0e-112	399	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
648286596	398	32.31	9	397	2	383	1.0e-74	273	COG0006	Xaa-Pro aminopeptidase	384
648286597	384	29.26	7	384	17	408	2.0e-56	213	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648286598	213	31.92	1	213	11	220	2.0e-20	92.5	COG1802	DNA-binding transcriptional regulator, GntR family	230
648286599	346	25.14	5	337	6	372	6.0e-23	101	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648286600	223	36.32	4	220	7	239	1.0e-47	182	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
648286601	288	18.28	4	287	3	292	6.0e-06	45.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
648286602	199	52.48	1	198	2	197	4.0e-64	237	COG0605	Superoxide dismutase	204
648286603	201	27.78	22	182	31	188	2.0e-12	65.7	COG4583	Sarcosine oxidase gamma subunit	189
648286604	1012	36.59	613	1010	2	377	3.0e-93	337	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
648286605	107	47.06	1	83	1	84	5.0e-19	86.2	COG4311	Sarcosine oxidase delta subunit	97
648286608	414	27.92	29	404	1	387	8.0e-51	194	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648286609	412	31.86	3	297	2	271	5.0e-30	125	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
648286610	158	50.36	17	152	2	138	1.0e-38	152	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
648286611	75	46.67	11	70	6	64	5.0e-09	52.7	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
648286613	273	31.46	13	273	9	256	7.0e-10	58.1	COG0730	Uncharacterized membrane protein YfcA	258
648286614	315	39.19	1	290	18	301	1.0e-72	266	COG0042	tRNA-dihydrouridine synthase	323
648286617	341	30.18	5	329	1	303	2.0e-38	153	COG3547	Transposase	303
648286619	115	23.97	2	115	1	118	1.0e-10	58.6	COG3293	Transposase	124
648286623	583	20.55	210	456	71	317	2.0e-16	81.2	COG3472	Uncharacterized protein	342
648286627	326	27.04	107	302	55	231	1.0e-10	60.8	COG2801	Transposase InsO and inactivated derivatives	232
648286628	762	31.72	3	570	100	653	3.0e-106	379	COG0209	Ribonucleotide reductase alpha subunit	696
648286629	143	47.18	6	143	4	144	3.0e-36	144	COG5458	Uncharacterized protein	144
648286631	358	33.92	1	329	5	343	4.0e-68	251	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
648286633	302	48.81	4	298	8	300	1.0e-72	267	COG1079	ABC-type uncharacterized transport system, permease component	304
648286634	361	43.91	2	354	1	348	6.0e-70	258	COG4603	ABC-type uncharacterized transport system, permease component	356
648286635	507	47.81	2	496	1	501	0.0e+00	589	COG3845	ABC-type uncharacterized transport system, ATPase component	501
648286636	316	22.77	5	297	4	254	1.0e-22	100	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
648286638	460	52.7	3	460	9	490	0.0e+00	537	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
648286640	1174	45	4	1147	2	1118	0.0e+00	1155	COG0587	DNA polymerase III, alpha subunit	1139
648286642	490	34.51	9	487	1	429	2.0e-101	363	COG0124	Histidyl-tRNA synthetase	429
648286643	362	28.38	14	360	26	386	5.0e-26	112	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
648286644	230	31.14	1	228	1	209	4.0e-38	151	COG0040	ATP phosphoribosyltransferase	290
648286645	309	43.14	1	303	1	302	6.0e-76	277	COG0039	Malate/lactate dehydrogenase	313
648286646	74	51.67	15	74	9	67	5.0e-07	46.2	COG5481	Uncharacterized protein	67
648286647	136	37.3	14	133	21	145	3.0e-18	84.3	COG0071	Molecular chaperone IbpA, HSP20 family	146
648286648	75	31.17	3	75	11	85	3.0e-06	43.4	COG5568	Uncharacterized protein	85
648286649	350	43.18	127	344	1	216	2.0e-51	196	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
648286650	156	54.49	1	156	1	156	2.0e-52	198	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
648286651	626	26.69	252	509	75	336	3.0e-22	100	COG0642	Signal transduction histidine kinase	336
648286652	233	37.39	4	229	1	228	4.0e-43	168	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648286655	399	22.44	26	399	21	407	2.0e-24	107	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648286656	143	28.26	9	143	1	136	4.0e-17	80.7	COG0824	Acyl-CoA thioesterase FadM	137
648286658	301	31.45	8	290	1	256	1.0e-17	84.3	COG0730	Uncharacterized membrane protein YfcA	258
648286661	397	34.58	1	369	3	365	1.0e-21	98.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
648286662	1044	54.08	1	1027	2	1009	0.0e+00	1029	COG0841	Multidrug efflux pump subunit AcrB	1009
648286663	306	30.56	6	304	1	297	3.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
648286664	214	42.05	9	197	2	194	1.0e-60	225	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
648286665	291	25.79	1	215	9	219	3.0e-23	102	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648286666	798	39.38	159	797	13	650	0.0e+00	543	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
648286667	113	28.32	1	112	11	123	1.0e-12	65	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
648286668	375	32.63	6	373	2	371	7.0e-59	221	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
648286669	256	22.57	7	256	1	257	2.0e-06	46.9	COG0730	Uncharacterized membrane protein YfcA	258
648286670	562	45.29	177	562	5	388	2.0e-75	277	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648286671	494	58.5	1	494	4	496	0.0e+00	749	COG0554	Glycerol kinase	499
648286674	255	46.25	1	253	1	253	3.0e-67	248	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
648286675	277	29.38	10	142	7	166	1.0e-13	70.4	COG0681	Signal peptidase I	166
648286676	227	44.29	9	223	10	228	9.0e-58	216	COG0571	dsRNA-specific ribonuclease	235
648286679	301	47.49	1	298	2	298	3.0e-103	368	COG1159	GTPase Era, involved in 16S rRNA processing	298
648286680	110	34.26	3	104	2	109	1.0e-11	61.9	COG5447	Uncharacterized protein	115
648286681	145	45.83	1	144	6	147	9.0e-40	155	COG4125	Uncharacterized membrane protein	149
648286682	125	44.36	1	124	1	133	1.0e-24	105	COG3791	Uncharacterized conserved protein	133
648286683	256	35.8	1	240	1	239	6.0e-38	150	COG2186	DNA-binding transcriptional regulator, FadR family	241
648286684	152	44.97	5	151	2	149	2.0e-34	138	COG0314	Molybdopterin synthase catalytic subunit	149
648286685	82	42.86	1	82	1	84	7.0e-15	72.3	COG1977	Molybdopterin converting factor, small subunit	84
648286689	242	30.8	1	214	4	226	8.0e-33	133	COG1381	Recombinational DNA repair protein (RecF pathway)	251
648286691	445	36.04	42	445	5	408	9.0e-83	300	COG0004	Ammonia channel protein AmtB	409
648286692	112	60.71	1	112	1	112	3.0e-35	140	COG0347	Nitrogen regulatory protein PII	112
648286693	727	38.95	58	713	10	639	0.0e+00	490	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
648286694	777	44.59	33	477	1	461	2.0e-125	444	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648286695	123	50.98	11	112	3	104	8.0e-31	125	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
648286696	156	41.51	1	155	1	155	1.0e-40	159	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
648286697	267	36.57	1	266	4	268	2.0e-45	176	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
648286698	478	41.87	25	475	2	456	4.0e-121	428	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
648286699	137	34.68	2	123	10	129	6.0e-18	83.1	COG3791	Uncharacterized conserved protein	133
648286701	1537	55.83	743	1227	2	484	0.0e+00	602	COG0069	Glutamate synthase domain 2	485
648286704	213	45.1	3	206	2	202	3.0e-53	202	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
648286706	347	35.97	9	346	2	363	5.0e-63	235	COG3119	Arylsulfatase A or related enzyme	475
648286710	280	43.4	23	279	7	264	3.0e-71	261	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
648286711	929	31.14	3	929	1	852	0.0e+00	916	COG1049	Aconitase B	852
648286715	159	39.29	3	159	1	167	2.0e-31	128	COG0629	Single-stranded DNA-binding protein	167
648286725	263	40.4	112	258	2	147	8.0e-27	114	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
648286745	457	31.89	53	306	34	281	2.0e-40	160	COG0616	Periplasmic serine protease, ClpP class	317
648286746	533	33.01	6	510	1	464	6.0e-65	242	COG5511	Bacteriophage capsid protein	492
648286748	670	24.67	12	602	10	568	4.0e-57	216	COG5525	Phage terminase, large subunit GpA	611
648286761	229	33.51	35	224	13	184	2.0e-33	136	COG4725	N6-adenosine-specific RNA methylase IME4	198
648286787	563	36.36	4	563	1	543	8.0e-115	408	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
648286788	225	37.38	6	215	13	225	5.0e-28	117	COG1802	DNA-binding transcriptional regulator, GntR family	230
648286791	589	20.07	1	578	1	534	6.0e-48	185	COG2303	Choline dehydrogenase or related flavoprotein	542
648286793	574	19.03	55	520	21	432	5.0e-20	93.2	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648286794	91	62.22	3	91	9	97	1.0e-17	81.2	COG5477	Predicted small integral membrane protein	97
648286795	287	34.42	17	287	5	280	2.0e-50	193	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648286796	289	33.1	1	281	4	287	1.0e-47	183	COG1175	ABC-type sugar transport system, permease component	295
648286797	358	41.88	1	350	1	338	1.0e-98	353	COG3839	ABC-type sugar transport system, ATPase component	338
648286798	362	36.96	1	349	2	338	4.0e-86	311	COG3839	ABC-type sugar transport system, ATPase component	338
648286799	531	44.44	11	531	14	519	0.0e+00	483	COG0578	Glycerol-3-phosphate dehydrogenase	532
648286800	598	43.12	6	583	8	574	0.0e+00	610	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
648286801	438	38.6	19	438	11	440	7.0e-81	294	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
648286802	186	21.68	30	172	14	156	9.0e-10	56.9	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648286803	347	30	5	322	1	316	5.0e-44	171	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648286804	343	35.03	12	343	1	332	9.0e-70	257	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
648286805	319	42.61	4	285	3	275	9.0e-51	194	COG3734	2-keto-3-deoxy-galactonokinase	306
648286806	213	36.45	8	210	4	205	2.0e-41	162	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
648286807	640	20.88	33	417	1	353	1.0e-34	142	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
648286808	194	31.41	6	194	21	198	1.0e-17	83.1	COG5463	Uncharacterized conserved protein YgiB, involved in bioifilm formation, UPF0441/DUF1190 family	198
648286809	401	47.88	1	401	1	387	1.0e-122	433	COG0754	Glutathionylspermidine synthase	387
648286810	430	35.36	50	427	1	378	5.0e-62	231	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648286811	333	24.31	1	320	2	320	5.0e-30	125	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648286812	161	20.67	12	161	15	160	2.0e-07	48.8	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648286814	525	30.75	31	518	6	521	1.0e-98	353	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
648286815	223	27.43	1	222	25	245	2.0e-28	119	COG1414	DNA-binding transcriptional regulator, IclR family	246
648286816	142	30.17	18	130	19	132	3.0e-12	64.7	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
648286817	417	45.2	9	403	4	396	6.0e-109	388	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
648286818	356	25.96	1	347	12	368	4.0e-22	99.1	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
648286821	494	26	190	484	2	288	2.0e-25	110	COG0382	4-hydroxybenzoate polyprenyltransferase	289
648286824	727	38.99	1	689	1	794	0.0e+00	548	COG3280	Maltooligosyltrehalose synthase	889
648286825	271	41.43	23	267	1	250	4.0e-51	195	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648286826	265	35.98	3	258	1	249	1.0e-34	140	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648286828	443	30.83	4	368	1	371	2.0e-61	229	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
648286833	752	26.37	311	719	7	381	5.0e-33	136	COG1944	Ribosomal protein S12 methylthiotransferase accessory factor YcaO	398
648286835	304	44.59	1	304	9	322	2.0e-80	292	COG2907	Predicted NAD/FAD-binding protein	447
648286836	181	35.96	7	181	1	177	3.0e-24	104	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
648286837	222	33.62	1	220	7	238	7.0e-27	113	COG5343	Anti-sigma-K factor RskA	240
648286841	313	29.09	27	292	10	277	1.0e-41	163	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
648286843	325	22.76	1	282	2	291	3.0e-10	59.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
648286845	367	54.05	1	366	1	348	4.0e-119	421	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
648286848	217	51.89	5	216	6	217	1.0e-65	242	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
648286849	226	52.97	7	223	5	223	4.0e-65	241	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
648286850	201	56.72	1	201	1	189	3.0e-75	274	COG0066	3-isopropylmalate dehydratase small subunit	191
648286852	473	58.72	2	467	1	423	0.0e+00	634	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
648286853	317	24.74	7	287	6	292	7.0e-06	45.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
648286854	269	22.52	41	262	43	253	2.0e-11	63.2	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
648286855	200	42.71	1	199	1	169	3.0e-34	138	COG5352	Uncharacterized protein	169
648286856	167	39.44	14	150	5	146	1.0e-28	119	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
648286858	250	57.85	8	249	1	242	2.0e-81	295	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
648286859	152	26.17	2	150	3	148	5.0e-20	90.4	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
648286860	134	43.51	1	131	1	127	8.0e-36	142	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
648286861	356	50.57	8	353	1	350	3.0e-123	435	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
648286862	164	62.03	4	161	1	156	5.0e-56	210	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
648286863	286	27.1	46	252	4	200	2.0e-26	113	COG0625	Glutathione S-transferase	211
648286864	807	32.08	1	795	7	801	0.0e+00	622	COG1201	Lhr-like helicase	814
648286866	224	36.61	20	193	10	191	7.0e-28	117	COG1407	Metallophosphoesterase superfamily enzyme	235
648286867	135	28.15	1	135	5	137	5.0e-16	77	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
648286868	300	53.98	4	292	1	282	6.0e-107	380	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
648286869	98	38.78	1	97	1	98	2.0e-10	57.3	COG1605	Chorismate mutase	101
648286870	558	64.44	5	558	1	554	0.0e+00	880	COG2759	Formyltetrahydrofolate synthetase	554
648286872	237	38.11	2	237	17	255	4.0e-42	165	COG4106	Trans-aconitate methyltransferase	257
648286873	637	55.18	8	597	1	593	0.0e+00	715	COG0465	ATP-dependent Zn proteases	596
648286874	448	32.05	24	273	20	253	2.0e-34	140	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
648286875	276	28.2	3	268	9	256	8.0e-23	101	COG1729	Periplasmic TolA-binding protein (function unknown)	262
648286876	174	37.84	22	169	41	188	2.0e-28	118	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
648286877	446	36.74	21	445	5	424	7.0e-81	295	COG0823	Periplasmic component of the Tol biopolymer transport system	425
648286879	134	44.63	1	121	13	132	9.0e-31	125	COG0848	Biopolymer transport protein ExbD	137
648286880	231	43.93	19	230	1	214	2.0e-47	182	COG0811	Biopolymer transport protein ExbB/TolQ	216
648286881	129	42.31	1	129	4	132	1.0e-28	118	COG0824	Acyl-CoA thioesterase FadM	137
648286882	342	22.58	22	318	19	314	2.0e-16	80	COG1466	DNA polymerase III, delta subunit	334
648286883	161	17.33	11	148	12	161	8.0e-07	46.6	COG5468	Predicted secreted (periplasmic) protein	172
648286884	856	46.04	1	856	2	814	0.0e+00	933	COG0495	Leucyl-tRNA synthetase	814
648286885	423	23.8	5	416	1	380	1.0e-26	114	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648286888	402	34.73	8	396	5	408	3.0e-90	325	COG2081	Predicted flavoprotein YhiN	408
648286890	339	31.31	4	328	1	303	4.0e-36	145	COG3547	Transposase	303
648286892	287	34.72	3	284	2	282	2.0e-57	216	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
648286893	329	36.01	10	316	5	336	5.0e-48	185	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
648286894	493	22.2	3	493	6	565	5.0e-10	59.6	COG4655	Uncharacterized membrane protein	565
648286898	296	29.01	7	296	1	293	6.0e-27	115	COG0583	DNA-binding transcriptional regulator, LysR family	297
648286899	406	36.48	27	406	2	393	2.0e-76	279	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648286900	408	71.54	10	406	1	393	0.0e+00	700	COG0133	Tryptophan synthase beta chain	396
648286901	421	23.65	4	414	14	396	8.0e-36	145	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
648286902	191	42.42	1	98	1	99	4.0e-17	81.2	COG2863	Cytochrome c553	121
648286903	336	23.87	5	329	11	332	3.0e-27	116	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648286904	169	23.29	7	152	2	145	3.0e-11	61.5	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648286905	426	34.77	56	425	7	374	2.0e-59	223	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648286906	299	37.71	9	298	1	297	4.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
648286907	424	25.8	28	393	4	374	1.0e-38	154	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648286908	457	38.04	9	455	1	457	3.0e-87	316	COG0277	FAD/FMN-containing dehydrogenase	459
648286909	558	31.47	35	461	18	441	5.0e-53	202	COG0038	H+/Cl- antiporter ClcA	443
648286911	113	27.27	4	102	19	117	1.0e-16	78.1	COG2343	Uncharacterized conserved protein, DUF427 family	132
648286912	591	27.71	148	534	1	381	1.0e-55	211	COG0006	Xaa-Pro aminopeptidase	384
648286914	625	53.18	1	608	11	618	0.0e+00	595	COG4547	Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib...	620
648286916	327	18.21	19	311	1	289	5.0e-35	141	COG0714	MoxR-like ATPase	329
648286917	185	37.14	11	185	5	177	5.0e-24	104	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
648286918	232	28.95	10	226	11	237	1.0e-26	113	COG5343	Anti-sigma-K factor RskA	240
648286919	334	40.2	31	334	6	289	1.0e-63	237	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648286920	345	38.55	1	344	1	315	3.0e-77	282	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648286921	568	25.86	1	564	13	553	1.0e-62	234	COG0747	ABC-type transport system, periplasmic component	556
648286922	606	56.68	8	561	7	539	0.0e+00	696	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
648286923	264	32.86	24	235	3	212	4.0e-39	155	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
648286924	306	20.29	43	306	10	258	3.0e-09	56.1	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
648286925	388	27	1	388	9	407	3.0e-57	216	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648286926	445	28.11	19	439	1	387	1.0e-39	157	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648286927	388	49.22	8	383	8	387	2.0e-119	423	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
648286928	68	64.71	1	68	1	67	3.0e-21	93.3	COG1278	Cold shock protein, CspA family	67
648286930	418	55.58	1	418	2	412	0.0e+00	481	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
648286931	386	34.72	1	382	4	342	4.0e-80	291	COG1559	Cell division protein YceG, involved in septum cleavage	342
648286934	461	45.16	7	446	4	460	0.0e+00	537	COG0215	Cysteinyl-tRNA synthetase	464
648286935	545	34.88	3	431	1	409	9.0e-95	341	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
648286938	404	18.92	1	403	3	394	6.0e-06	45.6	COG2814	Predicted arabinose efflux permease, MFS family	394
648286939	430	40.38	2	193	56	267	1.0e-38	154	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
648286941	605	59.77	1	604	3	602	0.0e+00	914	COG1217	Predicted membrane GTPase involved in stress response	603
648286943	421	44	195	419	35	255	2.0e-50	193	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
648286944	258	45.96	9	243	14	241	2.0e-76	279	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
648286945	331	29.61	1	322	3	326	1.0e-39	157	COG4521	ABC-type taurine transport system, periplasmic component	334
648286946	462	39.69	15	460	7	444	3.0e-118	418	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
648286947	233	28.25	36	207	10	186	1.0e-21	96.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648286948	145	37.8	14	140	1	126	3.0e-11	61.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
648286949	95	47.83	4	95	1	92	3.0e-15	73.6	COG0776	Bacterial nucleoid DNA-binding protein	94
648286950	494	23.94	217	472	1	233	7.0e-38	152	COG0775	Nucleoside phosphorylase	234
648286951	289	38.73	9	289	1	282	5.0e-63	234	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
648286952	170	25.44	43	155	13	126	2.0e-08	51.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
648286953	233	39.3	7	233	2	228	1.0e-52	199	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648286954	308	46.3	1	303	2	309	4.0e-79	288	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
648286955	80	39.71	4	71	5	72	9.0e-09	51.9	COG1722	Exonuclease VII small subunit	81
648286956	289	38.25	1	289	2	322	5.0e-51	194	COG0142	Geranylgeranyl pyrophosphate synthase	322
648286957	641	56.67	7	633	2	623	0.0e+00	861	COG1154	Deoxyxylulose-5-phosphate synthase	627
648286959	364	55.79	175	364	6	193	1.0e-56	214	COG0807	GTP cyclohydrolase II	193
648286962	504	52.27	4	483	13	489	0.0e+00	606	COG0753	Catalase	496
648286969	179	37.01	11	162	12	165	6.0e-28	117	COG4333	Uncharacterized protein	167
648286970	323	46.11	2	320	8	325	4.0e-90	324	COG1171	Threonine dehydratase	347
648286971	484	24.77	21	449	8	435	2.0e-37	150	COG4097	Predicted ferric reductase	438
648286973	65	57.41	12	65	2	55	7.0e-14	68.7	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
648286974	215	42.79	1	212	2	215	6.0e-42	163	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
648286975	305	43.24	9	304	18	304	3.0e-64	238	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
648286976	223	32.53	1	221	10	256	1.0e-25	110	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
648286977	473	37.1	50	473	2	438	9.0e-80	291	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
648286978	262	39.47	5	262	3	261	4.0e-69	254	COG0708	Exonuclease III	261
648286979	343	43.11	3	341	8	347	9.0e-97	347	COG0407	Uroporphyrinogen-III decarboxylase	352
648286980	319	50.49	11	316	3	303	1.0e-95	342	COG0181	Porphobilinogen deaminase	307
648286981	486	36.18	5	340	36	370	7.0e-71	261	COG1686	D-alanyl-D-alanine carboxypeptidase	389
648286982	232	24.57	7	231	6	229	3.0e-20	92.3	COG1011	FMN phosphatase YigB, HAD superfamily	229
648286983	120	57.84	19	120	6	107	1.0e-31	128	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
648286985	210	34.76	5	207	90	299	2.0e-43	168	COG2813	16S rRNA G1207 methylase RsmC	300
648286986	266	33.08	4	256	2	251	2.0e-35	143	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648286987	298	46.94	9	297	5	278	9.0e-93	333	COG0408	Coproporphyrinogen III oxidase	303
648286988	204	40.87	1	203	1	208	1.0e-41	162	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
648286989	699	35.91	390	687	86	408	4.0e-41	163	COG0840	Methyl-accepting chemotaxis protein	408
648286990	565	52.87	1	564	8	581	0.0e+00	661	COG1001	Adenine deaminase	584
648286992	391	38.56	9	323	23	339	5.0e-76	278	COG2951	Membrane-bound lytic murein transglycosylase B	343
648286994	328	65.95	1	325	1	323	0.0e+00	504	COG0435	Glutathionyl-hydroquinone reductase	324
648287002	239	35.92	3	234	5	249	7.0e-49	187	COG0631	Serine/threonine protein phosphatase PrpC	262
648287008	343	18.6	7	313	34	363	1.0e-09	57.6	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
648287009	352	42.21	1	352	15	366	6.0e-96	344	COG5351	Uncharacterized protein	367
648287012	248	38.67	6	240	9	262	4.0e-51	194	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
648287013	180	33.07	29	151	2	128	3.0e-14	71.8	COG1695	DNA-binding transcriptional regulator, PadR family	138
648287015	423	45.09	47	423	1	375	5.0e-84	305	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648287016	163	29.29	1	140	9	148	2.0e-16	78.4	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648287017	324	31.79	1	322	4	326	4.0e-62	231	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648287018	241	31.44	2	222	13	241	2.0e-32	132	COG2186	DNA-binding transcriptional regulator, FadR family	241
648287019	295	29.81	86	292	18	222	6.0e-20	91.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
648287020	334	33.52	6	331	1	349	2.0e-55	209	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
648287021	368	30.4	2	346	12	375	8.0e-44	171	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
648287022	498	49.13	99	498	2	381	0.0e+00	462	COG2721	Altronate dehydratase	381
648287023	392	49.5	1	391	2	390	1.0e-124	439	COG0126	3-phosphoglycerate kinase	395
648287024	168	43.98	10	166	1	158	5.0e-43	166	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
648287025	183	43.14	24	175	1	147	7.0e-41	160	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
648287028	417	47.29	13	416	9	400	6.0e-122	431	COG0162	Tyrosyl-tRNA synthetase	401
648287029	362	38.79	2	362	1	370	5.0e-67	248	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
648287030	608	37.45	5	503	2	529	3.0e-129	455	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
648287031	350	29.31	8	338	14	339	6.0e-32	131	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
648287032	368	29.7	1	321	1	322	6.0e-62	231	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
648287033	224	25.33	8	224	7	211	6.0e-10	58.1	COG4912	3-methyladenine DNA glycosylase AlkD	222
648287034	605	53.63	1	605	1	597	0.0e+00	750	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
648287035	449	51.2	1	435	1	456	0.0e+00	547	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
648287036	220	34.4	1	216	4	218	5.0e-32	131	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
648287037	410	27.89	24	401	9	366	8.0e-51	194	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
648287038	325	38.99	8	324	1	260	1.0e-44	174	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
648287039	329	24.36	1	328	2	346	2.0e-22	100	COG0303	Molybdopterin biosynthesis enzyme	404
648287040	136	69.12	1	136	40	175	2.0e-51	194	COG0290	Translation initiation factor IF-3	176
648287042	292	26.57	33	290	9	266	7.0e-38	151	COG1018	Ferredoxin-NADP reductase	266
648287044	263	40.76	57	260	42	251	2.0e-48	186	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
648287045	557	37.57	1	542	1	507	7.0e-130	457	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
648287048	147	36.49	2	147	14	158	2.0e-20	91.3	COG2030	Acyl dehydratase	159
648287049	380	45.01	1	380	1	391	9.0e-87	314	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648287051	292	41.08	1	291	3	299	6.0e-69	254	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
648287052	325	39.21	1	324	2	329	7.0e-70	257	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648287053	170	32.73	5	169	5	169	5.0e-17	80.8	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648287054	428	45.93	45	425	1	379	4.0e-86	312	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648287056	496	30.57	1	494	6	527	6.0e-72	265	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648287057	309	41.72	3	304	2	313	4.0e-73	268	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
648287058	317	27.76	1	316	2	307	4.0e-28	118	COG0679	Predicted permease	311
648287059	554	41.16	4	552	2	549	0.0e+00	469	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
648287060	710	40.35	7	693	1	672	0.0e+00	518	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
648287061	430	43.12	51	427	1	378	5.0e-82	298	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648287062	207	19.08	56	206	20	171	4.0e-08	51.5	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648287063	335	30.77	8	330	6	326	5.0e-50	192	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648287064	525	48.18	3	522	1	520	0.0e+00	574	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
648287065	687	41.55	2	686	10	674	0.0e+00	533	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
648287067	114	33.88	1	114	8	128	1.0e-26	111	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
648287068	310	28.19	9	304	1	292	2.0e-33	136	COG0583	DNA-binding transcriptional regulator, LysR family	297
648287073	341	30.84	11	339	12	345	7.0e-27	114	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
648287074	505	51.62	5	497	4	495	0.0e+00	507	COG3333	TctA family transporter	504
648287076	323	33.02	1	323	1	319	2.0e-60	226	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
648287077	222	42.34	2	215	4	224	4.0e-48	184	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648287078	807	27.85	151	464	20	329	2.0e-33	137	COG0642	Signal transduction histidine kinase	336
648287079	338	43.88	8	336	1	333	6.0e-75	274	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
648287080	352	24.61	7	325	1	274	3.0e-30	126	COG1082	Sugar phosphate isomerase/epimerase	274
648287081	374	28.18	5	364	3	334	9.0e-47	181	COG0673	Predicted dehydrogenase	342
648287082	501	51.21	1	491	4	499	0.0e+00	567	COG1129	ABC-type sugar transport system, ATPase component	500
648287083	335	42.22	16	329	4	307	5.0e-47	181	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
648287084	311	30.28	1	311	10	322	1.0e-42	167	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
648287086	463	23.45	21	451	17	402	1.0e-27	117	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648287087	521	33.27	4	516	1	535	5.0e-82	298	COG0405	Gamma-glutamyltranspeptidase	539
648287088	327	46.67	1	300	1	258	2.0e-94	339	COG4608	ABC-type oligopeptide transport system, ATPase component	309
648287089	331	56.11	5	319	1	314	6.0e-118	417	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
648287090	298	50.7	16	298	9	288	5.0e-69	254	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
648287094	289	39.11	1	246	1	247	7.0e-54	204	COG1484	DNA replication protein DnaC	254
648287104	566	22.13	11	257	1	222	3.0e-15	77.5	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
648287109	338	37.74	4	306	1	309	4.0e-57	215	COG1984	Allophanate hydrolase subunit 2	314
648287110	250	33.19	14	238	1	223	9.0e-29	120	COG2049	Allophanate hydrolase subunit 1	223
648287111	420	31.05	9	418	27	463	5.0e-62	232	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
648287113	427	35.36	49	427	3	378	7.0e-64	238	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648287114	183	21.95	1	163	1	164	4.0e-08	51.4	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
648287115	347	23.05	1	324	1	316	7.0e-23	101	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648287116	271	58.27	6	257	9	262	3.0e-91	328	COG4336	Uncharacterized protein YcsI, UPF0317 family	265
648287117	293	26.8	4	290	3	290	8.0e-29	121	COG0583	DNA-binding transcriptional regulator, LysR family	297
648287119	234	39.08	2	230	10	247	8.0e-37	147	COG3503	Uncharacterized membrane protein	323
648287120	434	46.37	5	422	3	425	3.0e-127	448	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
648287121	577	22.65	11	577	5	554	6.0e-49	189	COG2831	Hemolysin activation/secretion protein	554
648287125	482	42.17	5	477	55	548	9.0e-104	370	COG1626	Neutral trehalase	558
648287129	259	32.54	11	258	10	254	5.0e-43	168	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
648287132	251	49.15	21	251	4	237	1.0e-71	263	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
648287133	251	40.08	3	249	4	250	1.0e-72	266	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
648287134	400	30.14	19	381	5	314	8.0e-36	144	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
648287135	343	32.06	1	340	3	295	9.0e-45	174	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
648287136	448	28.8	35	413	1	360	2.0e-40	160	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648287137	436	25.61	115	427	19	313	8.0e-18	85.3	COG3800	Predicted transcriptional regulator	332
648287140	891	23.43	1	466	1	462	3.0e-44	174	COG0591	Na+/proline symporter	493
648287142	141	41.41	1	127	3	130	4.0e-29	120	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
648287144	141	38.13	8	138	22	160	1.0e-05	42.3	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
648287145	288	24.11	1	218	10	223	5.0e-26	111	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648287146	116	33.04	3	115	6	120	2.0e-12	64.3	COG1734	RNA polymerase-binding transcription factor DksA	120
648287148	666	35.75	6	202	5	211	9.0e-29	122	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648287150	86	57.14	3	86	2	85	8.0e-17	78.4	COG3750	Uncharacterized conserved protein, UPF0335 family	85
648287152	552	32.3	10	549	1	530	3.0e-75	276	COG1178	ABC-type Fe3+ transport system, permease component	540
648287156	449	26.53	32	446	11	402	3.0e-45	176	COG1228	Imidazolonepropionase or related amidohydrolase	406
648287157	464	28.78	66	460	26	401	7.0e-46	178	COG1228	Imidazolonepropionase or related amidohydrolase	406
648287160	597	26.71	186	322	11	151	7.0e-10	59.5	COG5616	TolB amino-terminal domain (function unknown)	152
648287164	326	50.15	14	326	25	348	8.0e-100	357	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
648287165	707	38.82	7	705	14	653	0.0e+00	653	COG0209	Ribonucleotide reductase alpha subunit	696
648287166	137	56.15	1	130	1	130	5.0e-44	169	COG1780	Protein involved in ribonucleotide reduction	141
648287167	74	28.57	1	73	1	77	6.0e-13	65.8	COG0695	Glutaredoxin	80
648287168	346	36.42	8	330	7	326	1.0e-75	276	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
648287169	360	32.87	12	300	2	266	9.0e-63	234	COG1018	Ferredoxin-NADP reductase	266
648287170	412	33.93	21	407	5	363	6.0e-74	271	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
648287171	290	28.08	8	290	1	290	6.0e-29	121	COG0583	DNA-binding transcriptional regulator, LysR family	297
648287172	853	31.69	435	853	2	379	2.0e-75	277	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
648287173	318	38.91	2	311	14	320	2.0e-79	289	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
648287174	360	28.37	29	360	1	340	4.0e-48	185	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648287177	488	53.65	17	476	1	457	0.0e+00	606	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
648287178	475	46.61	6	456	1	456	0.0e+00	462	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
648287179	338	45.95	1	338	3	345	2.0e-72	266	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
648287182	454	57.21	1	452	1	455	0.0e+00	605	COG1066	Predicted ATP-dependent serine protease	456
648287186	255	50.8	7	253	7	255	1.0e-85	309	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
648287188	260	43.02	3	260	8	265	8.0e-52	197	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
648287189	345	41.5	1	344	2	360	2.0e-88	319	COG0787	Alanine racemase	360
648287190	494	39.91	20	483	3	433	3.0e-124	438	COG0305	Replicative DNA helicase	435
648287191	226	33.81	11	218	1	201	3.0e-40	158	COG0461	Orotate phosphoribosyltransferase	201
648287192	344	61.81	1	343	2	343	0.0e+00	522	COG0418	Dihydroorotase	344
648287193	399	28.26	3	186	1	179	4.0e-30	126	COG3038	Cytochrome b561	181
648287194	313	55.31	1	311	2	310	3.0e-86	312	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
648287195	245	47.24	2	243	1	251	6.0e-49	187	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648287196	77	60	1	75	3	77	8.0e-13	65.3	COG0236	Acyl carrier protein	80
648287197	333	27.27	36	332	1	299	6.0e-46	178	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
648287199	793	48.46	409	792	4	392	8.0e-122	431	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
648287200	272	39.29	1	267	24	301	7.0e-58	217	COG0010	Arginase family enzyme	305
648287202	349	58.5	1	348	3	361	0.0e+00	478	COG0216	Protein chain release factor A	363
648287203	282	42.76	1	278	1	275	4.0e-57	215	COG2890	Methylase of polypeptide chain release factors	280
648287205	278	48.08	19	277	2	254	3.0e-74	272	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
648287206	320	50	1	312	8	326	1.0e-96	346	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
648287207	408	18.35	6	276	1	275	3.0e-13	70.1	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
648287208	727	23.14	1	708	12	751	1.0e-58	221	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
648287209	364	27.99	1	364	2	364	2.0e-41	163	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
648287210	371	25.48	1	356	8	364	2.0e-34	140	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
648287211	491	44.47	48	487	37	485	8.0e-122	430	COG0260	Leucyl aminopeptidase	485
648287212	152	31.08	1	148	1	144	2.0e-22	98.1	COG2927	DNA polymerase III, chi subunit	144
648287213	193	32.34	5	193	16	215	4.0e-30	124	COG3577	Predicted aspartyl protease	215
648287214	206	47.52	1	202	2	199	3.0e-33	134	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
648287220	255	39.62	2	212	37	247	4.0e-48	185	COG1484	DNA replication protein DnaC	254
648287222	151	39.47	1	151	4	154	4.0e-26	110	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648287223	390	38.35	3	390	20	409	1.0e-67	250	COG2124	Cytochrome P450	411
648287224	583	36.35	9	579	3	602	6.0e-98	351	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
648287225	841	38.1	1	406	2	460	1.0e-92	335	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
648287226	233	26.39	13	228	6	177	8.0e-23	100	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648287227	458	43.36	52	450	5	378	1.0e-91	330	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648287228	249	50.79	1	247	1	250	3.0e-72	265	COG0149	Triosephosphate isomerase	251
648287229	126	48.11	7	110	2	107	4.0e-31	126	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
648287230	187	40.12	15	181	5	176	6.0e-28	117	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
648287231	559	17.89	261	541	10	283	4.0e-12	66.8	COG0668	Small-conductance mechanosensitive channel	316
648287232	118	47.47	20	117	12	110	3.0e-27	113	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
648287236	343	58.09	1	340	1	346	0.0e+00	468	COG0536	GTPase involved in cell partioning and DNA repair	369
648287237	368	50.81	3	368	2	368	1.0e-110	393	COG0263	Glutamate 5-kinase	369
648287238	421	55.9	9	421	3	417	0.0e+00	544	COG0014	Gamma-glutamyl phosphate reductase	417
648287239	200	27.92	8	198	14	209	6.0e-19	87.4	COG5385	Uncharacterized protein	214
648287241	252	35.12	10	244	40	280	2.0e-34	139	COG3176	Putative hemolysin	292
648287242	274	25.79	30	239	3	219	9.0e-17	81.1	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
648287243	208	29.76	6	206	3	205	2.0e-22	99.2	COG0352	Thiamine monophosphate synthase	211
648287244	247	41.28	8	242	5	234	6.0e-56	210	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
648287245	381	35.54	33	362	3	307	3.0e-45	176	COG1612	Heme A synthase	323
648287246	500	41.5	1	487	4	497	0.0e+00	482	COG2317	Zn-dependent carboxypeptidase, M32 family	497
648287247	285	23.63	3	274	2	293	2.0e-18	86.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
648287248	721	48.83	1	709	8	733	0.0e+00	841	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
648287249	287	26.88	35	209	35	218	2.0e-18	86.5	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
648287250	301	31.79	1	294	1	297	6.0e-35	141	COG0583	DNA-binding transcriptional regulator, LysR family	297
648287251	1150	29.74	29	704	4	634	0.0e+00	521	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
648287252	270	33.58	1	270	6	264	2.0e-52	199	COG0796	Glutamate racemase	269
648287253	149	40.43	7	145	4	144	3.0e-32	131	COG2332	Cytochrome c-type biogenesis protein CcmE	153
648287254	120	55.24	1	104	1	105	4.0e-39	153	COG0278	Glutaredoxin-related protein	105
648287255	80	36.36	1	80	1	85	2.0e-14	70.4	COG0271	Stress-induced morphogen (activity unknown)	90
648287256	260	47.73	1	259	1	260	2.0e-83	302	COG0708	Exonuclease III	261
648287261	347	25.38	4	321	6	313	3.0e-31	129	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648287262	246	31.78	12	244	8	235	7.0e-31	127	COG3473	Maleate cis-trans isomerase	238
648287263	229	35.21	18	229	15	226	3.0e-31	128	COG1802	DNA-binding transcriptional regulator, GntR family	230
648287265	209	50.79	10	200	6	196	1.0e-55	209	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
648287268	357	27.74	1	304	1	296	1.0e-23	104	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
648287269	513	45.67	15	507	5	499	0.0e+00	492	COG1129	ABC-type sugar transport system, ATPase component	500
648287270	325	37.9	15	325	4	315	2.0e-33	136	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
648287271	324	36.82	12	303	15	306	6.0e-35	141	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
648287272	258	40.94	8	256	1	251	6.0e-41	161	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648287273	249	42.52	1	238	1	251	6.0e-47	181	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648287275	365	39.57	1	362	2	356	2.0e-83	302	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
648287276	271	31.98	21	267	1	246	2.0e-39	156	COG1414	DNA-binding transcriptional regulator, IclR family	246
648287277	272	28.44	9	233	1	222	2.0e-26	113	COG1414	DNA-binding transcriptional regulator, IclR family	246
648287278	528	41.76	2	528	8	537	9.0e-127	447	COG2303	Choline dehydrogenase or related flavoprotein	542
648287279	368	23.31	1	266	2	244	2.0e-16	80.2	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
648287280	502	47.92	26	502	1	470	0.0e+00	487	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648287281	362	25.24	21	330	7	310	4.0e-17	82.5	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
648287282	161	25.81	25	147	1	124	3.0e-10	58.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
648287283	446	56.88	14	442	5	427	0.0e+00	553	COG3508	Homogentisate 1,2-dioxygenase	427
648287284	413	23.18	69	353	14	249	6.0e-22	98.9	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
648287285	322	16.74	21	240	6	225	2.0e-10	59.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648287286	209	33.83	6	201	3	201	2.0e-24	106	COG0625	Glutathione S-transferase	211
648287287	533	31.45	286	531	1	246	3.0e-26	113	COG1414	DNA-binding transcriptional regulator, IclR family	246
648287288	381	43.02	5	351	4	336	2.0e-91	329	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
648287290	344	33.93	2	333	19	349	3.0e-63	235	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
648287293	489	40.17	7	484	6	442	6.0e-89	321	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
648287294	180	25.36	5	135	2	137	2.0e-10	59.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
648287297	248	26.97	14	164	15	158	3.0e-13	68.9	COG3666	Transposase	161
648287298	393	22.73	52	357	16	303	6.0e-23	102	COG3547	Transposase	303
648287299	333	41.03	24	330	32	335	2.0e-70	259	COG3367	Uncharacterized conserved protein, NAD-dependent epimerase/dehydratase family	339
648287300	319	36.54	18	318	3	280	5.0e-61	228	COG2301	Citrate lyase beta subunit	283
648287302	452	42.72	11	414	5	400	2.0e-84	306	COG1301	Na+/H+-dicarboxylate symporter	415
648287303	461	31.86	160	450	1	316	8.0e-59	221	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
648287304	609	52.29	1	609	8	572	0.0e+00	774	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
648287306	139	42.75	2	139	15	151	5.0e-29	120	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648287307	199	27.67	1	199	1	206	2.0e-18	86.1	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
648287308	320	58.6	1	314	1	313	2.0e-123	435	COG0825	Acetyl-CoA carboxylase alpha subunit	317
648287309	346	38.18	1	346	1	315	3.0e-72	265	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
648287310	570	38.73	1	563	4	554	0.0e+00	546	COG0143	Methionyl-tRNA synthetase	558
648287311	304	38.54	3	300	5	271	1.0e-62	233	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
648287312	273	23.47	1	265	1	274	2.0e-14	72.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648287313	225	30.7	1	225	2	226	3.0e-27	115	COG1011	FMN phosphatase YigB, HAD superfamily	229
648287314	142	42.86	3	141	2	140	3.0e-33	134	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
648287315	262	25.09	1	258	2	281	9.0e-18	84	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648287317	317	26.11	15	311	5	335	6.0e-18	84.9	COG0015	Adenylosuccinate lyase	438
648287318	96	39.58	1	95	8	103	9.0e-07	45.2	COG0640	DNA-binding transcriptional regulator, ArsR family	110
648287319	633	32.87	16	576	2	533	1.0e-94	340	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648287322	143	32.79	19	140	5	126	4.0e-11	60.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
648287323	519	34.14	3	517	1	514	8.0e-85	308	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
648287326	112	57.8	2	109	5	113	3.0e-30	123	COG3502	Uncharacterized conserved protein, DUF952 family	115
648287327	352	42.49	43	345	1	305	5.0e-78	284	COG0167	Dihydroorotate dehydrogenase	310
648287328	112	30.97	1	112	3	115	4.0e-21	93.3	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
648287329	406	29.9	4	394	11	423	3.0e-46	179	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
648287330	186	32.07	1	179	1	178	5.0e-22	97.3	COG1514	2'-5' RNA ligase	180
648287331	274	52.05	9	252	1	237	8.0e-79	286	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
648287333	430	19.27	17	339	2	320	8.0e-18	85.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648287334	358	32.52	26	350	6	314	9.0e-34	138	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
648287336	317	31.58	19	316	5	297	1.0e-34	140	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
648287337	288	45.82	36	286	3	250	5.0e-84	304	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
648287338	654	31.47	10	614	17	611	8.0e-120	424	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
648287343	85	48.15	1	81	2	79	1.0e-16	78.5	COG0271	Stress-induced morphogen (activity unknown)	90
648287345	152	46.51	26	152	1	129	6.0e-48	183	COG0229	Peptide methionine sulfoxide reductase MsrB	140
648287346	184	41.01	7	184	18	183	2.0e-33	135	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
648287347	391	52.65	15	390	1	376	1.0e-117	416	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
648287349	180	58.56	3	180	5	185	2.0e-47	182	COG3709	Ribose 1,5-bisphosphokinase PhnN	192
648287350	230	62.39	1	230	1	234	1.0e-86	312	COG4778	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL	235
648287351	256	75.59	3	256	5	258	1.0e-116	412	COG4107	ABC-type phosphonate transport system, ATPase component	258
648287352	292	75.26	2	287	4	290	0.0e+00	491	COG3627	Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase	291
648287353	361	65.22	1	361	1	367	0.0e+00	525	COG3626	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI	367
648287354	189	44.27	5	188	5	196	1.0e-35	142	COG3625	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH	196
648287355	151	56.67	5	151	2	151	2.0e-38	151	COG3624	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG	151
648287356	251	36.91	1	233	3	234	1.0e-46	179	COG2188	DNA-binding transcriptional regulator, GntR family	236
648287357	393	35.36	25	354	18	357	4.0e-54	205	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
648287359	203	30.23	7	173	20	190	1.0e-20	93	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
648287360	435	36.91	204	433	52	283	2.0e-49	190	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
648287361	286	35.43	27	280	35	282	5.0e-45	175	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
648287362	299	33.22	1	296	4	293	8.0e-55	207	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
648287363	272	50.58	1	256	3	257	2.0e-89	322	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
648287365	353	36.42	9	353	2	313	2.0e-71	263	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
648287366	341	26.27	15	336	3	334	6.0e-41	161	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
648287367	194	40.84	3	193	4	194	2.0e-39	155	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
648287368	391	27.5	3	316	30	327	1.0e-32	134	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
648287369	453	26.68	1	366	6	335	5.0e-38	152	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
648287370	360	32.56	141	355	51	251	7.0e-35	141	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
648287371	565	48.41	1	251	1	242	2.0e-80	293	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
648287374	721	57.32	7	713	99	793	0.0e+00	918	COG1251	NAD(P)H-nitrite reductase, large subunit	793
648287375	110	44.66	1	101	3	105	2.0e-23	101	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
648287377	320	31.03	15	315	12	325	2.0e-38	153	COG0547	Anthranilate phosphoribosyltransferase	338
648287378	247	31.36	12	243	4	235	3.0e-37	148	COG3473	Maleate cis-trans isomerase	238
648287379	196	32.28	19	196	67	251	2.0e-16	78.9	COG4544	Uncharacterized conserved protein	260
648287380	395	25.9	32	323	43	344	3.0e-12	66.5	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
648287381	415	28.4	14	415	1	366	6.0e-39	155	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648287382	238	32.5	5	230	7	239	2.0e-32	133	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
648287383	339	47.76	7	318	1	266	3.0e-96	345	COG4608	ABC-type oligopeptide transport system, ATPase component	309
648287384	618	50.15	299	615	1	316	5.0e-111	395	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
648287385	308	47.73	1	306	11	315	1.0e-79	290	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
648287386	506	28.41	6	504	16	556	1.0e-69	257	COG0747	ABC-type transport system, periplasmic component	556
648287387	532	43.95	10	532	2	533	0.0e+00	483	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
648287388	700	43.59	14	697	3	672	0.0e+00	558	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
648287389	221	33.5	11	209	12	211	1.0e-26	113	COG1802	DNA-binding transcriptional regulator, GntR family	230
648287393	852	43.65	38	553	8	526	2.0e-127	450	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
648287394	319	36.17	4	230	3	233	2.0e-44	173	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
648287395	348	26.29	1	347	9	355	3.0e-21	96.5	COG0628	Predicted PurR-regulated permease PerM	355
648287396	372	32.05	4	367	1	365	6.0e-69	254	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
648287398	499	40.42	6	483	3	469	4.0e-123	435	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648287399	298	27.85	4	291	2	295	2.0e-25	110	COG0583	DNA-binding transcriptional regulator, LysR family	297
648287401	165	53.09	1	162	2	158	3.0e-53	201	COG0669	Phosphopantetheine adenylyltransferase	159
648287405	333	62.16	2	331	1	332	0.0e+00	462	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
648287408	179	37.37	1	177	2	191	3.0e-35	141	COG3658	Cytochrome b	192
648287410	157	30	1	156	8	167	5.0e-14	70.8	COG1495	Disulfide bond formation protein DsbB	170
648287411	192	36.25	1	160	1	157	3.0e-23	101	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
648287412	678	38.91	4	676	1	612	0.0e+00	518	COG3894	Uncharacterized 2Fe-2 and 4Fe-4S clusters-containing protein, contains DUF4445 domain	614
648287413	380	45.31	1	380	4	383	7.0e-95	341	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
648287414	326	36.89	16	313	1	299	2.0e-50	192	COG0010	Arginase family enzyme	305
648287415	334	33.54	10	324	5	302	4.0e-32	132	COG3547	Transposase	303
648287416	482	30.59	254	471	1	170	7.0e-32	132	COG0516	IMP dehydrogenase/GMP reductase	170
648287417	384	32.89	111	380	49	351	2.0e-48	186	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
648287420	211	34.65	3	195	38	237	1.0e-31	129	COG5530	Uncharacterized membrane protein	247
648287422	521	67.08	203	521	1	315	0.0e+00	536	COG0519	GMP synthase, PP-ATPase domain/subunit	315
648287425	384	20.19	1	384	14	440	3.0e-31	129	COG2067	Long-chain fatty acid transport protein	440
648287427	317	49.84	1	303	1	303	6.0e-122	430	COG1897	Homoserine trans-succinylase	307
648287428	316	30.18	38	313	1	282	1.0e-19	90.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648287429	289	56.81	13	269	18	270	2.0e-90	325	COG2326	Polyphosphate kinase 2, PPK2 family	270
648287430	204	25.63	1	199	3	201	2.0e-11	62.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648287431	370	25.65	5	370	3	378	7.0e-25	108	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648287434	162	60.63	36	162	4	130	1.0e-46	179	COG0103	Ribosomal protein S9	130
648287435	152	58.78	1	147	1	148	3.0e-52	197	COG0102	Ribosomal protein L13	148
648287436	474	26.7	20	465	1	453	1.0e-61	231	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
648287438	142	29.58	1	141	1	141	6.0e-21	93.6	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
648287439	261	32.57	1	259	4	257	8.0e-42	164	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648287442	958	67.51	7	950	6	935	0.0e+00	1551	COG0178	Excinuclease UvrABC ATPase subunit	935
648287443	120	33.63	9	120	3	109	3.0e-13	67.3	COG0607	Rhodanese-related sulfurtransferase	110
648287444	231	23.36	9	212	1	214	8.0e-20	90.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
648287446	173	42.07	1	163	2	152	7.0e-35	140	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
648287447	938	25.31	57	937	12	730	3.0e-60	227	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
648287448	377	23.12	3	368	1	386	2.0e-16	80.2	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
648287449	865	17.78	1	858	1	895	2.0e-14	75.1	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
648287450	274	23.3	1	273	4	281	8.0e-30	124	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
648287451	181	43.58	3	180	2	173	3.0e-33	134	COG0431	NAD(P)H-dependent FMN reductase	184
648287452	449	29.75	11	442	16	451	8.0e-52	198	COG0534	Na+-driven multidrug efflux pump	455
648287453	169	24.83	22	169	13	141	6.0e-11	60.8	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
648287454	141	31.39	1	137	3	136	2.0e-21	95.1	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
648287455	123	28.33	6	123	1	119	5.0e-11	59.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
648287456	132	37.17	7	117	1	111	1.0e-12	65.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
648287457	593	31.86	34	456	6	393	2.0e-66	247	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648287461	340	52.29	11	334	23	348	6.0e-114	404	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
648287462	461	55.25	138	460	1	323	0.0e+00	466	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
648287464	446	41.83	1	445	1	402	1.0e-99	356	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
648287465	395	36.1	5	386	8	391	7.0e-46	178	COG2814	Predicted arabinose efflux permease, MFS family	394
648287466	272	55.49	84	265	5	186	2.0e-65	242	COG1045	Serine acetyltransferase	194
648287471	210	47.57	26	210	1	184	1.0e-55	209	COG5448	Uncharacterized protein	184
648287475	140	47.01	1	134	1	134	5.0e-37	146	COG5437	Predicted secreted protein	138
648287477	107	29.52	1	105	8	107	6.0e-10	56.1	COG5614	Bacteriophage head-tail adaptor	109
648287479	393	40.64	29	393	50	421	1.0e-73	270	COG4653	Predicted phage phi-C31 gp36 major capsid-like protein	422
648287480	180	28.73	12	177	17	193	1.0e-22	99.7	COG3740	Phage head maturation protease	194
648287482	399	39.95	17	387	14	381	1.0e-77	283	COG4695	Phage portal protein BeeE	398
648287483	160	30.77	9	136	3	138	3.0e-08	51.8	COG1247	L-amino acid N-acyltransferase YncA	169
648287484	434	53.47	29	432	29	408	1.0e-102	367	COG5323	Large terminase phage packaging protein	410
648287486	475	53.4	1	474	1	463	0.0e+00	560	COG1282	NAD/NADP transhydrogenase beta subunit	463
648287487	507	51.71	1	350	17	353	3.0e-108	385	COG3288	NAD/NADP transhydrogenase alpha subunit	356
648287488	151	28.77	6	151	37	182	2.0e-15	75.1	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
648287489	315	18.18	51	277	16	241	4.0e-10	59.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648287490	248	33.62	1	227	3	224	5.0e-34	138	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
648287491	397	54.29	8	387	23	407	6.0e-125	440	COG3844	Kynureninase	407
648287492	152	54.3	1	149	2	152	5.0e-52	196	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
648287493	745	22.91	137	737	93	720	3.0e-58	220	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
648287495	180	29.52	1	166	1	164	3.0e-29	121	COG4635	Protoporphyrinogen IX oxidase, menaquinone-dependent (flavodoxin domain)	175
648287496	258	39.84	1	248	1	243	2.0e-56	212	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
648287497	120	37.93	3	118	28	141	6.0e-17	79.5	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
648287498	274	39.91	1	231	15	247	2.0e-53	202	COG1484	DNA replication protein DnaC	254
648287500	119	31.53	5	115	18	123	1.0e-08	52	COG3293	Transposase	124
648287502	236	47.12	10	217	4	211	4.0e-47	181	COG3316	Transposase (or an inactivated derivative)	215
648287504	333	34.88	3	323	9	309	3.0e-63	236	COG0630	Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase	312
648287505	708	31.12	87	608	104	587	1.0e-95	344	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
648287510	105	30.19	2	103	19	124	3.0e-09	53.4	COG2372	Copper-binding protein CopC (methionine-rich)	127
648287511	292	27.47	27	289	16	288	7.0e-13	68	COG1276	Putative copper export protein	289
648287512	255	39.34	22	79	10	70	5.0e-09	55	COG0695	Glutaredoxin	80
648287515	424	34.03	2	424	43	449	6.0e-60	225	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
648287518	442	26.43	16	401	16	414	1.0e-16	81.3	COG0531	Amino acid transporter	466
648287519	128	28.45	13	128	20	135	5.0e-14	69.9	COG3439	Uncharacterized conserved protein, DUF302 family	137
648287521	228	22.16	15	207	1	183	2.0e-14	72.8	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
648287523	682	49.55	6	679	71	709	0.0e+00	713	COG2217	Cation transport ATPase	713
648287524	407	47.62	24	401	14	375	6.0e-94	338	COG3328	Transposase (or an inactivated derivative)	379
648287526	541	41.29	110	263	7	157	4.0e-27	116	COG3436	Transposase	157
648287533	346	31.03	37	232	5	202	6.0e-15	75.3	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
648287534	246	29.23	1	245	2	257	4.0e-29	121	COG1192	Cellulose biosynthesis protein BcsQ	259
648287536	293	47.9	7	281	11	294	3.0e-73	268	COG4227	Antirestriction protein ArdC	316
648287541	652	35.68	415	651	9	249	2.0e-43	171	COG1484	DNA replication protein DnaC	254
648287543	407	47.62	24	401	14	375	6.0e-94	338	COG3328	Transposase (or an inactivated derivative)	379
648287544	296	20.42	29	266	7	225	8.0e-12	64.6	COG2801	Transposase InsO and inactivated derivatives	232
648287547	331	18.34	2	243	32	314	2.0e-06	47	COG4249	Uncharacterized protein, contains caspase domain	380
648287553	361	25.66	14	164	15	158	3.0e-12	66.6	COG3666	Transposase	161
648287556	690	20.33	13	193	1	174	9.0e-15	76	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
648287557	341	30.18	5	329	1	303	2.0e-38	153	COG3547	Transposase	303
648287560	407	71.39	1	407	3	410	0.0e+00	674	COG2871	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF	410
648287561	201	56.4	1	201	1	198	3.0e-53	201	COG2209	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE	198
648287562	217	70.73	2	206	4	208	8.0e-83	299	COG1347	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD	208
648287563	269	46.85	19	267	7	259	2.0e-68	252	COG2869	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC	264
648287564	399	56	2	394	1	399	2.0e-114	406	COG1805	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB	400
648287565	395	48.61	3	395	53	447	3.0e-116	412	COG1726	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA	447
648287566	329	39.09	1	327	12	335	1.0e-82	300	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
648287571	507	25.44	236	505	6	282	2.0e-14	74	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648287573	226	51.38	9	226	5	221	3.0e-64	238	COG0289	Dihydrodipicolinate reductase	266
648287574	131	31.93	12	128	3	118	9.0e-17	79.1	COG0858	Ribosome-binding factor A	118
648287575	248	49.8	1	246	5	249	3.0e-72	265	COG3698	Uncharacterized protein YigE, DUF2233 family	250
648287576	448	36.28	11	448	7	454	1.0e-84	307	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
648287577	260	33.58	3	257	2	260	3.0e-42	165	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
648287579	414	29.28	27	381	45	403	1.0e-42	167	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
648287580	329	41.84	4	327	6	332	8.0e-70	257	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
648287581	288	39.25	11	275	11	261	5.0e-53	201	COG3741	N-formylglutamate amidohydrolase	272
648287584	276	24.32	1	273	11	306	4.0e-25	109	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
648287585	223	49.05	5	214	3	208	2.0e-58	218	COG0135	Phosphoribosylanthranilate isomerase	208
648287587	93	53.76	1	93	2	93	4.0e-26	109	COG0776	Bacterial nucleoid DNA-binding protein	94
648287590	553	53.45	1	548	2	541	0.0e+00	558	COG0539	Ribosomal protein S1	541
648287591	330	32.27	1	309	1	309	3.0e-63	235	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
648287592	207	46.36	1	202	3	222	7.0e-55	206	COG0283	Cytidylate kinase	222
648287594	447	44.34	10	444	5	428	3.0e-111	395	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
648287595	237	34.48	13	237	3	225	5.0e-47	181	COG0220	tRNA G46 methylase TrmB	227
648287596	392	59.9	2	388	1	382	0.0e+00	565	COG0192	S-adenosylmethionine synthetase	388
648287597	502	36.53	4	492	18	512	1.0e-74	274	COG0815	Apolipoprotein N-acyltransferase	518
648287599	160	43.66	18	159	19	150	3.0e-31	127	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
648287600	326	47.71	1	324	8	332	8.0e-93	333	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
648287603	435	48.64	5	435	3	436	0.0e+00	505	COG0621	tRNA A37 methylthiotransferase MiaB	437
648287605	166	23.95	3	160	10	175	5.0e-08	50.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648287606	228	27.04	3	227	6	230	1.0e-24	106	COG1018	Ferredoxin-NADP reductase	266
648287607	127	28.23	1	122	12	133	2.0e-18	84.2	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
648287608	169	30.19	13	169	1	147	5.0e-33	133	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
648287611	413	46.38	5	411	2	411	2.0e-115	409	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
648287612	263	61.57	4	258	3	256	6.0e-104	370	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
648287613	187	46.52	1	187	2	180	8.0e-56	209	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
648287614	229	43.91	4	228	14	242	2.0e-42	165	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
648287616	816	43.69	29	702	1	649	0.0e+00	617	COG0210	Superfamily I DNA or RNA helicase	655
648287617	1147	62.22	4	1147	7	1148	0.0e+00	1730	COG1038	Pyruvate carboxylase	1149
648287618	133	26.72	15	128	1	108	2.0e-12	64.6	COG0607	Rhodanese-related sulfurtransferase	110
648287623	324	39.32	1	324	1	349	4.0e-77	281	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
648287625	222	24.24	12	203	11	207	3.0e-18	85.4	COG0811	Biopolymer transport protein ExbB/TolQ	216
648287626	118	28.44	1	107	18	123	9.0e-07	45.6	COG0848	Biopolymer transport protein ExbD	137
648287628	379	21.6	169	376	34	237	1.0e-06	47.8	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
648287630	351	45.66	3	344	2	343	2.0e-97	349	COG3720	Putative heme degradation protein	349
648287633	359	46.88	21	355	3	331	1.0e-54	207	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
648287634	262	51.35	1	254	1	257	3.0e-76	278	COG4559	ABC-type hemin transport system, ATPase component	259
648287635	106	36.14	1	83	2	84	8.0e-17	78.8	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
648287636	323	51.74	1	315	3	311	2.0e-110	392	COG0435	Glutathionyl-hydroquinone reductase	324
648287637	273	45.77	19	273	8	267	2.0e-69	255	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
648287638	136	35.51	1	136	6	141	1.0e-06	45.4	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
648287639	314	34.23	20	312	3	295	4.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
648287641	351	21.57	11	343	16	352	5.0e-21	95.4	COG0628	Predicted PurR-regulated permease PerM	355
648287642	232	22.28	15	194	8	199	4.0e-11	61.8	COG0300	Short-chain dehydrogenase	265
648287643	798	26.72	8	785	74	860	0.0e+00	692	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
648287644	339	50.3	3	336	2	323	1.0e-105	376	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
648287645	153	44.44	1	153	3	154	1.0e-33	135	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648287649	447	45.89	1	447	5	461	1.0e-117	416	COG1109	Phosphomannomutase	464
648287650	336	45.9	72	334	8	270	4.0e-67	248	COG0294	Dihydropteroate synthase	274
648287651	303	28.57	25	140	2	120	3.0e-12	66.4	COG1539	Dihydroneopterin aldolase	121
648287653	851	24.12	28	847	20	740	5.0e-111	395	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
648287654	741	44.13	1	741	3	691	0.0e+00	738	COG0751	Glycyl-tRNA synthetase, beta subunit	691
648287657	309	66.67	5	286	1	270	0.0e+00	475	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
648287659	116	41.82	1	110	7	116	2.0e-15	74.4	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
648287660	241	48.91	13	241	2	229	1.0e-55	209	COG1346	Putative effector of murein hydrolase	230
648287661	461	21.59	6	456	8	438	5.0e-48	185	COG2610	H+/gluconate symporter or related permease	442
648287663	340	63.61	1	338	3	338	0.0e+00	515	COG0059	Ketol-acid reductoisomerase	338
648287664	151	35.76	1	151	5	154	6.0e-20	90.1	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648287665	154	40.69	5	149	4	147	1.0e-23	102	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648287666	374	30.23	24	373	29	364	2.0e-61	230	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
648287667	397	30.58	1	395	1	385	1.0e-47	184	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
648287669	214	22.87	6	213	1	222	5.0e-21	94.6	COG1011	FMN phosphatase YigB, HAD superfamily	229
648287670	214	38.31	11	208	21	221	2.0e-28	119	COG1802	DNA-binding transcriptional regulator, GntR family	230
648287671	616	26.71	179	589	4	422	9.0e-46	178	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
648287672	379	55.61	6	379	1	362	0.0e+00	521	COG0505	Carbamoylphosphate synthase small subunit	368
648287673	155	44.74	1	152	1	148	1.0e-33	135	COG1610	Uncharacterized conserved protein YqeY	148
648287675	165	28.03	6	160	9	160	1.0e-14	72.6	COG5488	Uncharacterized membrane protein	164
648287676	249	27.37	6	181	3	140	9.0e-08	50.8	COG0622	Predicted phosphodiesterase	172
648287677	557	52.81	18	548	7	517	0.0e+00	562	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
648287680	216	45.37	1	216	9	212	1.0e-73	269	COG0321	Lipoate-protein ligase B	221
648287683	149	46.15	1	141	12	153	1.0e-23	102	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
648287684	155	25.98	11	137	22	129	3.0e-07	48	COG2010	Cytochrome c, mono- and diheme variants	150
648287685	315	60.34	4	298	1	294	9.0e-113	399	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
648287686	204	44.17	1	204	4	208	5.0e-21	94.6	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
648287689	130	61.16	8	125	27	147	2.0e-35	140	COG0328	Ribonuclease HI	154
648287690	206	42.79	1	206	3	209	2.0e-42	165	COG2860	Uncharacterized membrane protein YeiH	209
648287691	392	42.97	5	392	4	388	2.0e-118	419	COG1168	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	388
648287692	173	50.6	1	168	2	168	1.0e-55	208	COG0242	Peptide deformylase	168
648287693	165	47.71	1	151	1	153	5.0e-42	163	COG0242	Peptide deformylase	168
648287694	164	41.92	1	164	1	167	4.0e-40	157	COG0242	Peptide deformylase	168
648287696	415	46.27	14	343	11	340	4.0e-81	295	COG2951	Membrane-bound lytic murein transglycosylase B	343
648287697	228	28.57	15	222	10	212	3.0e-12	65.7	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
648287702	188	30.29	4	165	7	174	1.0e-23	103	COG4186	Calcineurin-like phosphoesterase superfamily protein	186
648287707	400	35.42	19	384	15	371	1.0e-76	280	COG3328	Transposase (or an inactivated derivative)	379
648287710	318	29.15	1	318	15	331	4.0e-61	228	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
648287711	244	28.57	16	223	6	212	4.0e-25	108	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
648287713	330	23.81	1	309	6	311	8.0e-31	128	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
648287714	279	31.54	21	278	1	258	2.0e-42	166	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
648287715	286	27.5	45	284	27	255	2.0e-33	136	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
648287717	267	49.42	11	267	1	248	3.0e-85	308	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
648287718	484	35.19	1	445	1	430	3.0e-115	408	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
648287720	684	45.35	9	595	6	584	0.0e+00	632	COG0514	Superfamily II DNA helicase RecQ	590
648287723	445	36.02	2	443	8	434	1.0e-82	300	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
648287724	306	46.31	48	287	27	268	2.0e-72	266	COG3770	Murein endopeptidase	284
648287725	303	29.73	26	290	56	335	2.0e-22	100	COG4246	Uncharacterized protein	340
648287726	213	30.77	9	213	30	229	6.0e-23	101	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
648287729	250	35.68	12	216	17	228	1.0e-30	126	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
648287730	454	33.26	28	454	3	436	4.0e-116	411	COG0621	tRNA A37 methylthiotransferase MiaB	437
648287731	203	45.6	1	192	3	195	5.0e-68	250	COG1435	Thymidine kinase	201
648287732	231	23.66	1	221	3	222	6.0e-25	107	COG1183	Phosphatidylserine synthase	234
648287733	215	35.42	9	194	1	192	2.0e-33	136	COG2808	Predicted FMN-binding regulatory protein PaiB	209
648287734	417	37.91	6	417	7	433	2.0e-118	419	COG0621	tRNA A37 methylthiotransferase MiaB	437
648287735	279	42.22	11	270	1	270	2.0e-76	279	COG0253	Diaminopimelate epimerase	272
648287739	392	41.58	2	392	1	392	1.0e-78	287	COG0183	Acetyl-CoA acetyltransferase	392
648287740	414	42.49	2	345	10	342	6.0e-79	288	COG2951	Membrane-bound lytic murein transglycosylase B	343
648287741	680	33.78	8	657	1	652	4.0e-119	422	COG0210	Superfamily I DNA or RNA helicase	655
648287742	601	45.16	61	600	10	538	0.0e+00	545	COG0405	Gamma-glutamyltranspeptidase	539
648287744	599	40.87	20	594	1	567	0.0e+00	463	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
648287745	510	51.19	1	506	1	501	0.0e+00	623	COG3046	Uncharacterized protein related to deoxyribodipyrimidine photolyase	505
648287746	50	67.44	1	43	1	43	7.0e-09	52	COG4338	Uncharacterized protein	54
648287747	133	41.09	1	129	1	128	2.0e-23	101	COG4852	Uncharacterized membrane protein	134
648287749	235	30.36	2	233	13	259	1.0e-33	136	COG0300	Short-chain dehydrogenase	265
648287750	390	43.3	105	389	1	283	1.0e-72	266	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
648287751	262	32.82	1	253	1	256	2.0e-30	126	COG3496	Uncharacterized conserved protein, DUF1365 family	261
648287754	1078	34.71	2	1078	27	1115	0.0e+00	924	COG0587	DNA polymerase III, alpha subunit	1139
648287755	564	55.93	10	338	7	334	1.0e-109	390	COG0206	Cell division GTPase FtsZ	338
648287756	286	46.49	1	269	26	292	3.0e-79	288	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
648287757	275	39.73	29	252	29	252	1.0e-53	203	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
648287758	553	43.35	4	552	1	553	0.0e+00	483	COG0497	DNA repair ATPase RecN	557
648287759	443	34.79	18	443	2	418	6.0e-93	334	COG0849	Cell division ATPase FtsA	418
648287760	299	24.91	11	285	11	263	2.0e-19	90.5	COG1589	Cell division septal protein FtsQ	269
648287761	271	38.75	2	268	31	317	1.0e-64	239	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
648287762	314	41.14	16	310	2	288	2.0e-79	289	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
648287764	316	36.06	111	312	1	202	3.0e-36	145	COG1573	Uracil-DNA glycosylase	202
648287765	410	61.27	4	410	1	404	0.0e+00	551	COG4277	Predicted DNA-binding protein with the Helix-hairpin-helix motif	404
648287766	244	33.13	45	209	38	192	3.0e-23	102	COG0518	GMP synthase - Glutamine amidotransferase domain	198
648287767	592	19.8	104	592	37	458	2.0e-28	121	COG0471	Di- and tricarboxylate transporter	461
648287768	270	51.31	1	267	1	263	9.0e-96	343	COG1692	Calcineurin-like phosphoesterase	266
648287770	107	37.38	1	106	1	102	4.0e-15	73.2	COG0633	Ferredoxin	102
648287773	494	42.34	24	378	11	345	2.0e-71	263	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
648287774	500	32.92	165	461	87	404	7.0e-39	155	COG0840	Methyl-accepting chemotaxis protein	408
648287775	63	34.48	6	63	5	62	5.0e-06	42.9	COG3242	Uncharacterized conserved protein YjeT, DUF2065 family	62
648287776	352	30.41	4	292	3	290	6.0e-33	135	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
648287777	384	26.9	84	368	4	286	7.0e-39	155	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
648287778	485	36.57	3	479	2	454	2.0e-119	423	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
648287779	260	54.7	6	237	1	226	8.0e-70	257	COG0120	Ribose 5-phosphate isomerase	227
648287781	190	27.44	1	162	18	175	3.0e-10	58.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648287783	434	35.69	3	324	1	310	2.0e-80	293	COG0167	Dihydroorotate dehydrogenase	310
648287784	426	35.78	10	425	6	451	6.0e-93	334	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
648287785	206	51.94	1	203	1	203	8.0e-56	210	COG0522	Ribosomal protein S4 or related protein	205
648287786	273	33.33	23	265	3	247	3.0e-48	185	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
648287787	391	47.52	1	391	1	392	8.0e-92	330	COG0183	Acetyl-CoA acetyltransferase	392
648287789	240	40.73	3	237	6	250	5.0e-45	174	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648287791	57	52.63	1	57	1	57	2.0e-07	46.9	COG5570	Uncharacterized protein	57
648287792	247	32.91	6	239	13	243	1.0e-39	156	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
648287794	331	38.72	10	331	1	322	1.0e-78	286	COG0142	Geranylgeranyl pyrophosphate synthase	322
648287795	293	40.56	1	279	2	281	1.0e-64	240	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
648287797	406	39.1	8	378	1	322	1.0e-85	310	COG0523	GTPase, G3E family	323
648287799	844	32.04	1	431	2	417	2.0e-47	184	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
648287800	96	42.71	1	96	2	95	1.0e-22	98.1	COG2154	Pterin-4a-carbinolamine dehydratase	101
648287801	399	54.66	10	393	8	386	0.0e+00	465	COG3146	Predicted N-acyltransferase	387
648287802	249	31.65	9	231	7	230	3.0e-28	118	COG0584	Glycerophosphoryl diester phosphodiesterase	257
648287803	153	34.25	7	152	1	128	1.0e-17	82.6	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
648287805	576	48.63	12	558	13	561	0.0e+00	610	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
648287806	237	36.21	1	236	10	247	1.0e-39	156	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
648287807	200	23.19	1	200	2	202	2.0e-17	82.2	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
648287808	162	40.96	1	162	1	165	9.0e-44	169	COG0678	Peroxiredoxin	165
648287810	185	44.5	1	183	2	184	3.0e-47	181	COG0742	16S rRNA G966 N2-methylase RsmD	187
648287811	322	22.37	92	319	25	233	7.0e-12	64.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648287812	276	32.13	1	273	15	290	7.0e-42	164	COG1175	ABC-type sugar transport system, permease component	295
648287813	276	39.29	1	276	2	281	7.0e-48	184	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648287814	333	52.92	1	329	1	338	6.0e-124	437	COG3839	ABC-type sugar transport system, ATPase component	338
648287815	261	39.77	3	258	2	250	1.0e-36	146	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648287816	497	44.47	22	494	2	473	0.0e+00	468	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
648287817	357	38.23	3	355	7	364	8.0e-68	251	COG3490	Uncharacterized protein	366
648287818	327	27.75	5	327	16	359	2.0e-35	143	COG3489	Predicted periplasmic lipoprotein	359
648287819	514	55.32	48	514	13	481	0.0e+00	573	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
648287820	161	59.06	1	149	1	149	6.0e-49	186	COG2193	Bacterioferritin (cytochrome b1)	157
648287822	419	66.99	3	419	31	446	0.0e+00	548	COG3487	Uncharacterized iron-regulated protein	446
648287827	244	40.44	41	217	58	240	8.0e-41	160	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
648287829	594	26.67	355	579	2	219	1.0e-31	131	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
648287830	184	35.15	6	164	18	182	5.0e-29	120	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
648287832	266	25.21	142	256	7	124	2.0e-10	59.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
648287835	465	30.33	78	464	13	377	3.0e-52	199	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648287837	346	21.96	1	331	6	331	5.0e-24	105	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648287838	656	43.29	74	638	1	528	0.0e+00	644	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
648287839	228	40.57	12	223	3	178	7.0e-47	180	COG0563	Adenylate kinase or related kinase	178
648287840	87	43.53	3	87	5	88	5.0e-19	86.2	COG4327	Uncharacterized membrane protein	101
648287841	592	38.46	5	586	8	529	4.0e-120	425	COG4147	Na+(or H+)/acetate symporter ActP	529
648287842	607	34.32	6	600	3	604	1.0e-123	437	COG2905	Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains	610
648287845	412	27.95	15	379	1	307	5.0e-40	158	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
648287846	246	60.98	1	246	2	246	3.0e-94	337	COG4674	ABC-type uncharacterized transport system, ATPase component	249
648287847	231	45.22	1	228	3	232	6.0e-76	276	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
648287848	450	20.26	1	449	4	429	9.0e-21	95.1	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648287849	413	35.98	176	412	55	292	3.0e-48	186	COG1175	ABC-type sugar transport system, permease component	295
648287850	407	35.14	134	406	9	281	2.0e-50	193	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648287852	341	58.19	1	336	1	338	4.0e-126	444	COG3839	ABC-type sugar transport system, ATPase component	338
648287853	125	44.44	1	124	1	126	3.0e-16	77.5	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
648287854	350	32.62	4	324	1	288	6.0e-62	231	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
648287855	225	37.84	1	219	2	219	5.0e-39	154	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
648287856	237	47.83	1	227	27	256	1.0e-51	196	COG5387	Chaperone required for the assembly of the mitochondrial F1-ATPase	264
648287857	339	31.66	1	253	3	256	6.0e-28	118	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
648287858	410	46.48	15	410	16	397	1.0e-96	346	COG4597	ABC-type amino acid transport system, permease component	397
648287859	438	36.97	229	437	19	222	1.0e-41	164	COG0765	ABC-type amino acid transport system, permease component	222
648287860	249	61.51	9	247	3	240	2.0e-115	408	COG1126	ABC-type polar amino acid transport system, ATPase component	240
648287861	62	54.55	5	59	1	55	2.0e-11	60.9	COG1841	Ribosomal protein L30/L7E	55
648287862	192	55.37	1	177	5	181	8.0e-58	216	COG0098	Ribosomal protein S5	181
648287863	119	56.67	4	119	7	125	1.0e-28	118	COG0256	Ribosomal protein L18	125
648287864	152	58.94	2	151	27	176	7.0e-47	179	COG0097	Ribosomal protein L6P/L9E	178
648287865	130	52.67	1	130	3	132	1.0e-42	165	COG0096	Ribosomal protein S8	132
648287866	101	49.18	41	101	1	61	9.0e-16	75.3	COG0199	Ribosomal protein S14	61
648287867	186	57.87	8	184	1	177	3.0e-66	244	COG0094	Ribosomal protein L5	180
648287868	103	50.94	1	102	1	104	2.0e-17	80.7	COG0198	Ribosomal protein L24	104
648287869	122	77.87	1	122	1	122	2.0e-48	184	COG0093	Ribosomal protein L14	122
648287870	76	47.3	1	74	6	79	8.0e-17	78.7	COG0186	Ribosomal protein S17	87
648287871	68	58.73	3	65	5	67	3.0e-10	57.2	COG0255	Ribosomal protein L29	69
648287875	137	63.04	1	136	2	139	4.0e-48	183	COG0197	Ribosomal protein L16/L10AE	146
648287876	236	61.14	12	221	1	211	3.0e-76	278	COG0092	Ribosomal protein S3	233
648287877	126	58.41	12	124	8	120	1.0e-29	122	COG0091	Ribosomal protein L22	120
648287878	92	60.22	1	92	1	93	4.0e-34	136	COG0185	Ribosomal protein S19	93
648287879	280	61.68	1	274	1	274	4.0e-106	377	COG0090	Ribosomal protein L2	275
648287880	89	53.85	1	89	4	94	4.0e-20	89.9	COG0089	Ribosomal protein L23	94
648287882	72	69.44	1	72	1	72	1.0e-23	101	COG0361	Translation initiation factor IF-1	75
648287883	294	29.79	1	276	3	262	2.0e-29	122	COG0388	Predicted amidohydrolase	274
648287886	148	30.34	5	145	2	139	8.0e-23	99.6	COG0394	Protein-tyrosine-phosphatase	139
648287887	159	53.85	4	159	11	160	5.0e-48	183	COG5328	Uncharacterized protein, UPF0262 family	160
648287889	433	54.21	5	432	4	425	0.0e+00	527	COG0141	Histidinol dehydrogenase	425
648287892	423	60.05	1	423	1	421	0.0e+00	572	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
648287895	298	43.86	118	276	9	179	8.0e-37	147	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
648287896	553	35.51	5	550	2	546	6.0e-127	448	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
648287899	716	36.03	1	696	4	708	0.0e+00	563	COG0643	Chemotaxis protein histidine kinase CheA	716
648287900	154	33.33	1	150	6	155	2.0e-32	131	COG0835	Chemotaxis signal transduction protein	165
648287901	289	41.11	17	280	1	266	5.0e-69	254	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
648287904	351	31.66	16	344	14	350	2.0e-48	187	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
648287905	174	50.31	1	154	1	161	8.0e-45	173	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
648287906	240	51.05	1	237	1	236	6.0e-72	264	COG3484	Predicted proteasome-type protease	255
648287907	276	29.25	1	268	11	303	2.0e-31	129	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
648287908	317	36.36	1	316	1	311	5.0e-66	244	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
648287909	474	54.91	9	474	12	478	0.0e+00	624	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
648287910	429	31.37	17	382	1	361	7.0e-61	228	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
648287911	569	43.38	351	567	3	219	9.0e-51	195	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
648287912	109	43.27	1	104	2	105	1.0e-17	81.7	COG2076	Multidrug transporter EmrE and related cation transporters	106
648287914	380	43.8	17	376	1	352	1.0e-114	406	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
648287916	179	40.76	1	179	1	183	4.0e-40	157	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648287917	335	22.03	54	322	2	295	2.0e-13	70.2	COG4974	Site-specific recombinase XerD	300
648287939	670	24.67	12	602	10	568	2.0e-57	217	COG5525	Phage terminase, large subunit GpA	611
648287941	533	32.94	6	505	1	459	7.0e-65	242	COG5511	Bacteriophage capsid protein	492
648287942	457	31.89	53	306	34	281	2.0e-40	160	COG0616	Periplasmic serine protease, ClpP class	317
648287952	282	46.97	14	275	3	253	1.0e-79	290	COG0024	Methionine aminopeptidase	255
648287953	292	35.02	22	286	26	302	8.0e-37	147	COG0668	Small-conductance mechanosensitive channel	316
648287954	442	36.11	1	441	1	467	2.0e-81	296	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
648287955	417	41.85	15	409	1	387	4.0e-71	262	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
648287956	339	23.85	12	334	1	334	3.0e-30	126	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
648287958	249	39.46	3	222	4	225	3.0e-44	171	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
648287959	202	41.51	1	202	6	216	2.0e-31	129	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
648287960	219	42.34	1	218	1	222	2.0e-53	202	COG2135	Putative SOS response-associated peptidase YedK	226
648287962	358	41.6	230	354	2	125	4.0e-28	119	COG1803	Methylglyoxal synthase	142
648287963	117	23.96	23	117	35	128	1.0e-13	68.4	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
648287964	597	33.72	7	596	9	538	4.0e-112	398	COG0405	Gamma-glutamyltranspeptidase	539
648287965	417	30.85	28	415	1	381	4.0e-70	259	COG0006	Xaa-Pro aminopeptidase	384
648287966	672	43.54	6	671	1	731	0.0e+00	594	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
648287967	183	34.07	6	180	8	188	2.0e-24	105	COG3554	Uncharacterized protein	190
648287968	1809	36.6	296	1809	95	1619	0.0e+00	969	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
648287969	855	40.16	312	564	94	335	6.0e-43	169	COG0642	Signal transduction histidine kinase	336
648287972	709	38.24	83	702	32	669	1.0e-122	434	COG3563	Capsule polysaccharide export protein KpsC/LpsZ	671
648287973	383	25.85	47	280	12	239	6.0e-23	102	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
648287974	430	31.78	7	390	12	393	7.0e-60	224	COG3562	Capsule polysaccharide modification protein KpsS	403
648287975	195	47.45	1	194	1	194	3.0e-62	231	COG0307	Riboflavin synthase alpha chain	204
648287977	114	38.38	13	110	1	99	1.0e-06	45.2	COG0640	DNA-binding transcriptional regulator, ArsR family	110
648287979	245	42.13	9	223	16	220	8.0e-30	124	COG0785	Cytochrome c biogenesis protein CcdA	220
648287980	194	20.12	31	190	20	175	9.0e-17	80	COG2143	Thioredoxin-related protein	182
648287985	565	27.38	116	535	46	471	4.0e-59	222	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
648287987	408	45.93	275	407	1	130	3.0e-30	126	COG3474	Cytochrome c2	135
648287989	306	37.2	3	295	6	296	1.0e-59	223	COG1230	Co/Zn/Cd efflux system component	296
648287990	210	67.34	11	209	2	200	4.0e-79	287	COG0740	ATP-dependent protease ClpP, protease subunit	200
648287991	421	72.06	16	421	1	408	0.0e+00	705	COG1219	ATP-dependent protease Clp, ATPase subunit	408
648287992	119	29.03	1	115	2	125	1.0e-16	78.8	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
648287993	127	45.53	12	127	2	118	2.0e-22	98.3	COG3761	NADH:ubiquinone oxidoreductase 17.2 kD subunit	118
648287996	212	48.72	3	192	22	214	3.0e-64	238	COG2360	Leu/Phe-tRNA-protein transferase	221
648287998	163	45.03	13	163	1	139	8.0e-24	103	COG0511	Biotin carboxyl carrier protein	140
648288007	424	35.94	3	415	19	447	1.0e-101	363	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
648288009	463	23.77	25	452	37	446	1.0e-41	164	COG0527	Aspartokinase	447
648288010	314	35.52	4	291	1	288	5.0e-35	141	COG0583	DNA-binding transcriptional regulator, LysR family	297
648288011	737	61.6	20	736	14	730	0.0e+00	1068	COG0376	Catalase (peroxidase I)	730
648288013	303	43.58	1	295	4	299	2.0e-55	209	COG1079	ABC-type uncharacterized transport system, permease component	304
648288014	357	42.69	3	350	1	349	1.0e-67	250	COG4603	ABC-type uncharacterized transport system, permease component	356
648288015	503	46.32	4	497	3	501	0.0e+00	570	COG3845	ABC-type uncharacterized transport system, ATPase component	501
648288016	365	29.03	7	337	7	344	4.0e-51	195	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
648288017	451	33.18	1	437	1	420	3.0e-56	213	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
648288018	224	33.82	1	200	1	202	7.0e-24	104	COG0625	Glutathione S-transferase	211
648288022	294	65.37	1	282	5	287	0.0e+00	465	COG0788	Formyltetrahydrofolate hydrolase	287
648288023	438	38.08	3	438	5	443	1.0e-119	423	COG0174	Glutamine synthetase	443
648288024	216	23.62	15	212	5	201	1.0e-07	50.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648288025	286	28.07	1	282	13	291	1.0e-26	113	COG0583	DNA-binding transcriptional regulator, LysR family	297
648288026	310	29.41	126	309	10	190	6.0e-23	101	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
648288027	189	26.14	11	182	3	177	2.0e-21	95.2	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
648288029	240	37.7	5	237	3	245	7.0e-56	210	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
648288030	235	50	1	232	1	228	1.0e-70	259	COG1489	DNA-binding protein, stimulates sugar fermentation	235
648288031	393	31.58	7	390	5	389	1.0e-68	253	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
648288033	195	25.15	5	175	8	176	7.0e-19	87.2	COG3932	Uncharacterized conserved protein	209
648288034	193	23.23	1	187	3	197	3.0e-18	85	COG2834	Outer membrane lipoprotein-sorting protein	211
648288035	196	42.86	1	192	5	194	5.0e-46	177	COG4764	Uncharacterized protein	197
648288036	108	63.37	6	106	13	113	9.0e-34	135	COG3785	Heat shock protein HspQ	116
648288037	359	36.64	1	359	2	341	2.0e-75	276	COG2008	Threonine aldolase	342
648288038	156	56.25	12	155	9	149	8.0e-45	172	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
648288039	310	41.42	1	307	1	303	3.0e-85	308	COG0196	FAD synthase	304
648288040	217	44.84	3	216	7	228	2.0e-65	242	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
648288044	104	60.61	1	99	6	103	2.0e-29	120	COG3492	Uncharacterized protein	104
648288045	245	45.2	1	245	8	255	7.0e-66	244	COG3931	Predicted N-formylglutamate amidohydrolase	263
648288046	478	47.88	1	465	4	475	0.0e+00	545	COG0469	Pyruvate kinase	477
648288048	66	53.12	1	64	1	64	4.0e-11	59.8	COG0291	Ribosomal protein L35	65
648288049	121	64.17	1	120	1	118	2.0e-40	158	COG0292	Ribosomal protein L20	118
648288053	187	35.36	7	181	1	177	2.0e-33	135	COG0431	NAD(P)H-dependent FMN reductase	184
648288054	335	52.55	2	331	1	331	1.0e-108	386	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
648288055	322	50.65	2	307	4	295	1.0e-75	276	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
648288056	672	52.25	17	672	10	662	0.0e+00	853	COG0021	Transketolase	663
648288060	424	67.69	1	424	1	421	0.0e+00	646	COG0148	Enolase	423
648288064	544	34.13	4	530	5	524	0.0e+00	491	COG0033	Phosphoglucomutase	524
648288067	680	48.64	3	680	14	694	0.0e+00	740	COG1523	Pullulanase/glycogen debranching enzyme	697
648288068	470	47.02	3	470	2	482	8.0e-130	457	COG0297	Glycogen synthase	487
648288069	409	45.32	1	406	7	390	0.0e+00	471	COG0448	ADP-glucose pyrophosphorylase	393
648288070	682	54.34	52	678	1	626	0.0e+00	745	COG0296	1,4-alpha-glucan branching enzyme	628
648288074	400	35.42	19	384	15	371	1.0e-76	280	COG3328	Transposase (or an inactivated derivative)	379
648288077	304	27.27	17	241	6	234	2.0e-17	83	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648288078	426	28.61	109	424	2	327	1.0e-33	137	COG0642	Signal transduction histidine kinase	336
648288079	104	62.14	1	100	1	101	9.0e-21	91.7	COG5467	Uncharacterized protein	104
648288080	253	54.1	1	243	1	241	9.0e-87	313	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
648288081	76	57.14	1	74	2	78	2.0e-23	100	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
648288082	345	33.54	1	320	4	315	3.0e-66	245	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
648288083	222	52.25	1	213	3	224	1.0e-83	302	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
648288084	567	34.51	2	557	8	600	1.0e-98	354	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
648288085	440	37.17	1	439	5	461	3.0e-103	369	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
648288090	192	52.88	1	103	1	103	3.0e-30	125	COG0261	Ribosomal protein L21	103
648288091	89	63.22	1	87	1	87	4.0e-29	119	COG0211	Ribosomal protein L27	87
648288092	188	28.9	19	183	3	175	3.0e-19	88.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648288096	356	53.35	1	339	6	335	8.0e-123	433	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
648288099	579	43.35	145	577	16	443	2.0e-114	406	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
648288101	332	50.6	1	329	1	331	1.0e-104	372	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
648288102	264	34.97	99	236	2	139	2.0e-24	106	COG0394	Protein-tyrosine-phosphatase	139
648288103	463	29.61	183	453	22	321	1.0e-47	184	COG0280	Phosphotransacetylase	327
648288105	291	52.45	1	285	1	286	1.0e-97	349	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
648288106	293	23.5	32	247	16	227	4.0e-18	85.8	COG3176	Putative hemolysin	292
648288107	92	39.77	4	91	1	88	8.0e-18	81.8	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
648288108	132	34.07	1	131	1	135	3.0e-23	101	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
648288109	308	44.76	10	291	2	286	9.0e-81	293	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
648288111	576	30.77	241	576	17	329	2.0e-37	150	COG0642	Signal transduction histidine kinase	336
648288112	233	42.92	3	233	2	228	7.0e-56	210	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648288113	532	58.73	11	530	9	525	0.0e+00	739	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
648288115	166	31.93	1	166	1	166	1.0e-30	125	COG5465	Uncharacterized protein	166
648288118	440	43.97	1	440	10	446	0.0e+00	474	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
648288119	321	44.06	1	319	1	318	3.0e-93	335	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
648288121	141	29.53	1	141	4	151	2.0e-08	51.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
648288123	181	53.09	14	175	4	165	5.0e-53	200	COG1247	L-amino acid N-acyltransferase YncA	169
648288124	145	31.33	1	145	1	149	7.0e-08	50.2	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
648288125	556	47.96	18	555	11	542	1.0e-124	440	COG2985	Uncharacterized membrane protein YbjL, putative transporter	544
648288126	431	58.7	1	430	1	430	0.0e+00	622	COG0104	Adenylosuccinate synthase	430
648288128	338	43.69	12	328	10	332	7.0e-83	300	COG1171	Threonine dehydratase	347
648288130	387	41.99	6	382	1	346	5.0e-76	278	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
648288131	537	40.43	6	519	5	455	3.0e-118	419	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
648288132	521	36.96	1	511	31	540	2.0e-91	330	COG4987	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components	573
648288133	547	38.84	23	542	8	530	8.0e-98	351	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
648288134	188	34.07	34	167	1	134	8.0e-22	96.9	COG1959	DNA-binding transcriptional regulator, IscR family	150
648288139	428	24.15	1	427	4	433	5.0e-44	172	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
648288141	692	44.39	146	518	24	387	4.0e-116	412	COG2046	ATP sulfurylase (sulfate adenylyltransferase)	397
648288142	334	50.16	5	311	2	302	3.0e-88	318	COG0492	Thioredoxin reductase	305
648288143	166	40	1	155	1	154	2.0e-34	138	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648288146	251	42.46	1	251	1	247	2.0e-68	252	COG1496	Copper oxidase (laccase) domain	249
648288147	354	36.59	1	351	1	367	6.0e-74	271	COG1565	SAM-dependent methyltransferase, MidA family	370
648288148	295	40.59	1	295	2	277	2.0e-57	215	COG0682	Prolipoprotein diacylglyceryltransferase	287
648288149	81	40.26	1	77	10	86	2.0e-10	57.7	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
648288150	156	46.45	1	150	1	151	9.0e-29	119	COG0200	Ribosomal protein L15	152
648288151	447	48.37	7	428	10	432	4.0e-118	418	COG0201	Preprotein translocase subunit SecY	436
648288152	192	47.4	1	191	1	178	3.0e-46	177	COG0563	Adenylate kinase or related kinase	178
648288154	122	64.46	1	121	1	121	3.0e-45	173	COG0099	Ribosomal protein S13	121
648288155	130	70.77	1	130	1	129	1.0e-44	171	COG0100	Ribosomal protein S11	129
648288156	338	48.42	9	324	1	313	3.0e-95	341	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
648288157	139	64.66	1	116	1	116	1.0e-42	164	COG0203	Ribosomal protein L17	116
648288158	151	35.86	1	145	3	137	5.0e-26	110	COG5622	Protein required for attachment to host cells	139
648288160	462	41.71	5	354	2	337	2.0e-62	233	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
648288161	416	27.82	27	415	22	403	4.0e-38	152	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
648288162	62	47.83	3	44	10	55	3.0e-08	50.1	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
648288164	715	44.4	245	713	104	543	0.0e+00	480	COG2225	Malate synthase	545
648288165	602	62.17	99	594	1	497	0.0e+00	666	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
648288166	429	17.67	172	429	9	263	2.0e-06	47.6	COG1652	Nucleoid-associated protein YgaU, contains BON and LysM domains	269
648288167	183	32.09	1	183	12	197	7.0e-33	133	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
648288168	653	28.67	344	638	2	294	3.0e-24	107	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
648288169	286	49.31	1	285	9	296	4.0e-86	311	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
648288170	388	25.81	108	376	50	310	5.0e-15	75.9	COG2367	Beta-lactamase class A	329
648288171	161	36.55	5	148	14	153	9.0e-22	96.4	COG0597	Lipoprotein signal peptidase	167
648288173	457	30.95	19	448	7	434	2.0e-71	263	COG0612	Predicted Zn-dependent peptidase	438
648288174	439	30.96	9	436	3	438	2.0e-68	253	COG0612	Predicted Zn-dependent peptidase	438
648288175	529	60.92	9	529	4	515	0.0e+00	732	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
648288176	582	30.25	14	563	28	564	2.0e-71	263	COG5360	Uncharacterized conserved protein, heparinase superfamily	566
648288177	420	36.16	92	419	3	354	3.0e-63	236	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
648288179	89	57.83	7	89	8	90	4.0e-29	119	COG5425	Usg protein (tryptophan operon, function unknown)	90
648288180	905	50.67	5	893	2	802	0.0e+00	938	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
648288183	649	52.28	36	648	1	586	0.0e+00	710	COG0441	Threonyl-tRNA synthetase	589
648288184	103	55	2	81	16	94	4.0e-16	76.4	COG5572	Uncharacterized membrane protein	104
648288185	283	45.09	8	280	3	273	5.0e-81	294	COG3220	Uncharacterized conserved protein, UPF0276 family	282
648288188	106	33.98	1	93	3	105	5.0e-16	75.9	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
648288189	68	55.88	1	68	1	67	2.0e-21	93.7	COG1278	Cold shock protein, CspA family	67
648288190	301	32.54	3	295	1	291	6.0e-35	141	COG0583	DNA-binding transcriptional regulator, LysR family	297
648288191	288	40	2	280	13	291	4.0e-67	248	COG0685	5,10-methylenetetrahydrofolate reductase	291
648288193	263	34.23	1	242	6	263	3.0e-28	119	COG3769	Predicted mannosyl-3-phosphoglycerate phosphatase, HAD superfamily	274
648288195	215	49.76	8	212	3	208	7.0e-55	206	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
648288198	514	51.07	3	513	12	525	0.0e+00	608	COG5598	Trimethylamine:corrinoid methyltransferase	526
648288200	434	35.76	1	407	57	478	1.0e-105	377	COG0069	Glutamate synthase domain 2	485
648288201	237	23.86	13	237	29	291	1.0e-31	129	COG0070	Glutamate synthase domain 3	301
648288202	295	21.33	1	294	12	367	7.0e-44	171	COG0067	Glutamate synthase domain 1	371
648288204	383	42.26	5	381	2	377	5.0e-108	384	COG1454	Alcohol dehydrogenase, class IV	377
648288205	811	40.69	415	811	1	379	1.0e-95	344	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
648288206	292	24.83	17	290	9	262	3.0e-21	95.9	COG0510	Thiamine kinase and related kinases	269
648288207	787	38.87	400	783	1	379	1.0e-94	341	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
648288208	449	25.44	1	448	9	433	2.0e-64	239	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
648288209	339	33.7	7	339	16	366	6.0e-54	204	COG2021	Homoserine acetyltransferase	368
648288210	513	41.28	1	510	6	534	2.0e-108	386	COG2303	Choline dehydrogenase or related flavoprotein	542
648288211	400	28.61	8	399	14	411	3.0e-55	209	COG2124	Cytochrome P450	411
648288212	492	29.34	19	490	3	443	4.0e-82	299	COG0174	Glutamine synthetase	443
648288214	274	39.91	1	231	15	247	2.0e-53	202	COG1484	DNA replication protein DnaC	254
648288216	104	30.53	1	94	26	120	8.0e-11	58.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
648288221	482	38.77	20	467	5	454	2.0e-107	383	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
648288222	450	35.01	1	450	1	454	6.0e-97	347	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
648288223	112	57.55	5	110	2	107	6.0e-28	116	COG1742	Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily	109
648288229	409	26.33	106	398	1	292	5.0e-24	106	COG4974	Site-specific recombinase XerD	300
648288231	334	30.82	15	294	12	281	9.0e-43	167	COG4974	Site-specific recombinase XerD	300
648288233	750	31.04	6	747	43	765	3.0e-125	443	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
648288236	178	36.62	1	71	25	93	5.0e-08	51	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
648288238	388	37.17	7	388	1	359	3.0e-94	338	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
648288239	255	43.13	1	255	6	265	6.0e-38	151	COG0428	Zinc transporter ZupT	266
648288240	314	29.55	1	308	1	345	1.0e-66	247	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
648288241	263	54.2	1	259	1	262	2.0e-88	318	COG0159	Tryptophan synthase alpha chain	265
648288242	325	55.93	17	286	1	270	2.0e-101	362	COG2326	Polyphosphate kinase 2, PPK2 family	270
648288243	213	26.36	8	211	5	222	3.0e-12	65.4	COG5587	Uncharacterized conserved protein, DUF2461 family	228
648288244	794	43.45	1	790	1	749	0.0e+00	780	COG0058	Glucan phosphorylase	750
648288245	327	31.65	7	319	8	318	9.0e-59	220	COG0837	Glucokinase	320
648288246	443	37.89	5	432	1	444	1.0e-112	399	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
648288247	356	35.09	14	353	1	333	1.0e-63	237	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
648288248	454	17.92	45	453	22	429	9.0e-19	88.6	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
648288249	324	34.75	52	323	11	290	8.0e-44	171	COG1175	ABC-type sugar transport system, permease component	295
648288250	418	38.37	175	418	41	281	9.0e-57	214	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
648288251	551	37.52	23	521	1	498	6.0e-94	338	COG0366	Glycosidase	505
648288252	363	51.69	1	356	1	337	7.0e-115	407	COG3839	ABC-type sugar transport system, ATPase component	338
648288256	117	41.46	1	116	5	127	4.0e-21	93.1	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
648288257	204	39.13	1	193	1	207	1.0e-46	179	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
648288258	218	53	1	217	4	220	3.0e-37	148	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
648288259	242	35.65	6	234	41	269	1.0e-24	107	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
648288261	188	29.69	43	165	3	127	5.0e-10	57.6	COG0526	Thiol-disulfide isomerase or thioredoxin	127
648288264	259	41.98	1	234	2	241	1.0e-52	200	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
648288265	327	42.11	8	229	6	233	1.0e-51	197	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
648288266	202	38.35	3	199	4	207	8.0e-47	180	COG0352	Thiamine monophosphate synthase	211
648288267	252	53.94	2	252	10	262	2.0e-92	331	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
648288268	65	39.39	1	65	3	68	8.0e-11	58.7	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
648288269	315	29.81	1	303	6	364	4.0e-21	95.8	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648288270	594	66.08	119	567	3	431	0.0e+00	728	COG0422	Thiamine biosynthesis protein ThiC	432
648288273	287	44.6	1	286	45	318	2.0e-40	159	COG0530	Ca2+/Na+ antiporter	320
648288275	757	50.27	17	756	1	667	0.0e+00	843	COG0272	NAD-dependent DNA ligase	667
648288276	696	50.99	12	667	9	663	0.0e+00	767	COG1200	RecG-like helicase	677
648288278	150	27.86	10	148	6	145	2.0e-22	98.1	COG0822	NifU homolog involved in Fe-S cluster formation	150
648288279	120	60.78	6	106	9	110	3.0e-39	153	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
648288281	177	46.24	7	177	9	173	8.0e-36	143	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
648288283	446	56.79	1	441	6	437	0.0e+00	614	COG1206	Folate-dependent tRNA-U54 methylase TrmFO/GidA	439
648288301	381	61.38	38	369	1	333	5.0e-127	448	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
648288302	198	49.21	2	189	1	188	1.0e-64	239	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
648288304	385	43.48	4	369	1	361	2.0e-87	316	COG0349	Ribonuclease D	361
648288306	135	50.38	4	133	10	140	1.0e-37	148	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
648288307	321	41.87	1	312	1	330	5.0e-66	244	COG4307	Uncharacterized protein	349
648288309	430	50.93	1	426	1	428	0.0e+00	520	COG0172	Seryl-tRNA synthetase	429
648288310	247	20.51	10	224	9	227	3.0e-07	48.8	COG3591	V8-like Glu-specific endopeptidase	251
648288312	95	46.15	3	93	6	95	4.0e-21	93	COG1862	Preprotein translocase subunit YajC	97
648288313	562	44.86	64	562	22	506	2.0e-122	433	COG0342	Preprotein translocase subunit SecD	506
648288314	285	30.38	5	283	13	296	1.0e-36	147	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
648288315	220	31.33	14	219	15	245	2.0e-36	145	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
648288316	503	28.19	1	243	24	282	3.0e-21	96.9	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
648288317	315	36.88	7	280	33	301	8.0e-44	171	COG0501	Zn-dependent protease with chaperone function	302
648288318	377	44.36	7	263	2	247	2.0e-69	256	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
648288321	219	38.86	12	219	1	209	2.0e-46	178	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
648288322	127	49.11	1	109	1	111	3.0e-23	100	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
648288323	239	45.53	1	239	4	245	3.0e-56	211	COG3346	Cytochrome oxidase assembly protein ShyY1	252
648288325	390	27.16	84	388	1	309	6.0e-29	121	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
648288326	303	32.13	2	301	5	308	2.0e-28	120	COG0679	Predicted permease	311
648288327	285	29.79	9	283	1	281	2.0e-33	136	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
648288328	164	30	1	160	12	171	2.0e-16	78.4	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
648288329	427	47.89	47	426	1	379	2.0e-85	309	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648288330	342	38.76	2	337	6	332	2.0e-69	255	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648288331	413	24.57	57	402	25	325	5.0e-42	165	COG1171	Threonine dehydratase	347
648288332	409	25.42	9	407	4	409	8.0e-41	161	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648288333	302	33.22	3	299	1	272	8.0e-39	154	COG0388	Predicted amidohydrolase	274
648288335	463	28.54	60	462	1	379	3.0e-56	213	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648288339	581	39.25	2	569	65	650	3.0e-129	455	COG2943	Membrane glycosyltransferase	736
648288340	400	37.76	16	399	23	396	2.0e-62	233	COG4645	Uncharacterized protein	410
648288341	350	34.58	6	345	1	342	8.0e-69	254	COG0015	Adenylosuccinate lyase	438
648288342	392	25.06	5	384	2	379	2.0e-53	203	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
648288343	287	32.23	159	279	1	121	3.0e-18	86.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
648288344	278	29.67	1	275	1	296	6.0e-49	187	COG3246	Uncharacterized conserved protein, DUF849 family	298
648288345	230	44.59	3	230	22	226	9.0e-47	180	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
648288346	241	47.68	1	237	2	226	1.0e-66	246	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
648288347	128	33.87	6	126	1	124	8.0e-19	85.8	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
648288348	262	28.52	1	259	2	282	3.0e-24	105	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648288353	156	27.13	31	156	8	136	1.0e-08	53	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
648288354	342	22.22	38	300	3	266	1.0e-13	70.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
648288355	380	28.64	1	379	1	383	3.0e-57	216	COG0006	Xaa-Pro aminopeptidase	384
648288356	408	21.41	12	403	5	393	3.0e-25	109	COG2814	Predicted arabinose efflux permease, MFS family	394
648288357	510	58	1	510	11	526	0.0e+00	710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
648288362	891	53.02	1	889	5	875	0.0e+00	1099	COG0013	Alanyl-tRNA synthetase	879
648288363	90	50	2	90	7	96	6.0e-21	92.3	COG5470	Uncharacterized conserved protein, DUF1330 family	96
648288364	95	48.39	1	92	2	94	1.0e-19	88	COG5470	Uncharacterized conserved protein, DUF1330 family	96
648288366	316	59.6	7	308	6	306	0.0e+00	470	COG0320	Lipoate synthase	306
648288369	464	66.88	2	463	1	462	0.0e+00	753	COG0114	Fumarate hydratase class II	462
648288371	158	44.16	5	158	6	157	6.0e-37	146	COG3814	Uncharacterized protein	157
648288372	416	45.36	2	182	5	187	3.0e-30	126	COG2059	Chromate transport protein ChrA	195
648288375	409	26.33	106	398	1	292	5.0e-24	106	COG4974	Site-specific recombinase XerD	300
648288380	341	30.18	5	329	1	303	2.0e-38	153	COG3547	Transposase	303
648288390	194	34.12	39	188	1	167	7.0e-21	93.8	COG0807	GTP cyclohydrolase II	193
648288391	183	38	9	154	3	152	2.0e-30	125	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
648288392	163	33.56	19	162	10	149	1.0e-19	89.6	COG0781	Transcription termination factor NusB	151
648288394	652	47.76	9	652	1	635	0.0e+00	802	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
648288396	217	31.86	11	211	9	196	2.0e-20	93.1	COG1865	Adenosylcobinamide amidohydrolase	200
648288404	396	51.01	8	393	4	394	2.0e-127	449	COG0282	Acetate kinase	396
648288405	255	51	5	255	4	254	6.0e-82	297	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
648288406	283	35.02	9	282	3	269	7.0e-54	204	COG3757	Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family	269
648288407	412	45.83	8	412	1	385	1.0e-112	400	COG2309	Leucyl aminopeptidase (aminopeptidase T)	385
648288409	356	36.48	37	353	5	311	3.0e-53	202	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
648288410	331	29.11	3	318	19	316	7.0e-39	154	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
648288413	310	34.15	32	310	40	324	8.0e-55	207	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
648288414	303	24.41	1	289	1	293	2.0e-20	93.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
648288415	225	30.24	14	217	5	207	6.0e-23	101	COG0684	Regulator of RNase E activity RraA	210
648288416	428	44.71	47	423	1	378	1.0e-87	317	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
648288418	333	27.93	1	329	2	330	1.0e-51	197	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
648288419	269	28.4	8	252	5	234	5.0e-24	105	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
648288424	652	36.75	422	651	16	249	2.0e-43	170	COG1484	DNA replication protein DnaC	254
648288425	165	58.43	1	165	45	210	7.0e-64	236	COG0035	Uracil phosphoribosyltransferase	210
648288428	227	55.73	38	227	2	193	3.0e-67	248	COG3443	Periplasmic Zn/Cd-binding protein ZinT	193
648288429	541	34.39	17	540	8	527	1.0e-106	380	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648288432	234	30.6	5	234	7	234	2.0e-28	119	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
648288436	342	22.31	24	274	11	229	3.0e-17	83	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648288437	566	36.14	34	441	6	387	6.0e-67	248	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648288438	318	44.02	4	211	4	211	2.0e-58	219	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
648288440	261	47.1	2	257	3	260	5.0e-71	261	COG3622	Hydroxypyruvate isomerase	260
648288441	308	32.04	4	297	2	296	2.0e-36	146	COG0524	Sugar or nucleoside kinase, ribokinase family	311
648288442	457	38.58	6	456	1	459	7.0e-87	314	COG0277	FAD/FMN-containing dehydrogenase	459
648288443	245	31.8	3	237	7	242	5.0e-39	154	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
648288445	171	49.1	5	171	6	172	2.0e-42	165	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
648288446	207	42.31	1	205	1	208	4.0e-21	94.9	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
648288448	291	45.04	5	241	18	255	2.0e-64	239	COG0005	Purine nucleoside phosphorylase	262
648288449	542	36.4	28	514	18	526	1.0e-95	343	COG0659	Sulfate permease or related transporter, MFS superfamily	554
648288450	525	32.75	7	515	51	552	7.0e-87	315	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
648288451	364	37.82	1	357	1	338	1.0e-67	250	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
648288455	308	29.53	12	308	9	301	8.0e-32	131	COG2215	ABC-type nickel/cobalt efflux system, permease component RcnA	303
648288456	454	33.71	5	444	10	443	2.0e-55	210	COG0534	Na+-driven multidrug efflux pump	455
648288459	241	47.28	4	185	1	184	3.0e-62	231	COG0193	Peptidyl-tRNA hydrolase	190
648288460	103	34.34	1	99	2	97	9.0e-18	81.9	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
648288462	207	37.89	17	194	45	232	1.0e-38	153	COG3719	Ribonuclease I	249
648288463	258	47.6	4	252	5	230	2.0e-61	229	COG3820	Uncharacterized protein	230
648288464	197	46.11	6	197	6	198	6.0e-65	240	COG0353	Recombinational DNA repair protein RecR	198
648288469	225	48.4	1	218	1	215	5.0e-67	247	COG2884	ABC-type ATPase involved in cell division	223
648288471	265	26.24	21	239	46	256	3.0e-14	72.4	COG4584	Transposase	278
